# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Apolipoprotein PF01442.18 PVD18232.1 - 3.7e-09 36.7 1.9 0.012 15.5 0.3 4.2 3 1 1 4 4 4 3 Apolipoprotein A1/A4/E domain ATG_C PF09333.11 PVD18232.1 - 3.1e-06 27.4 3.6 14 6.1 0.1 8.3 3 3 5 8 8 8 1 Autophagy-related protein C terminal domain DUF842 PF05811.13 PVD18232.1 - 1.6e-05 24.6 0.0 2.4 7.8 0.0 4.9 2 1 2 5 5 5 1 Eukaryotic protein of unknown function (DUF842) Yae1_N PF09811.9 PVD18232.1 - 5.6e-05 22.8 9.0 0.43 10.3 0.3 7.8 6 1 0 6 6 6 1 Essential protein Yae1, N terminal Exonuc_VII_L PF02601.15 PVD18232.1 - 0.0036 16.9 17.4 8.7e+02 -0.7 17.4 3.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAD-SLDH PF12318.8 PVD18232.1 - 0.0058 16.7 15.3 0.31 11.1 0.6 5.2 2 1 5 7 7 7 1 Membrane bound FAD containing D-sorbitol dehydrogenase DUF2385 PF09539.10 PVD18232.1 - 0.63 10.6 20.4 2.4 8.8 0.2 7.2 3 3 6 9 9 9 0 Protein of unknown function (DUF2385) KxDL PF10241.9 PVD18232.1 - 0.94 9.8 15.3 1.1 9.5 0.2 5.4 4 1 3 7 7 7 0 Uncharacterized conserved protein PIN_8 PF18476.1 PVD18232.1 - 1.2 8.9 3.3 69 3.2 0.1 3.6 2 1 1 4 4 4 0 PIN like domain DUF2379 PF09543.10 PVD18232.1 - 1.2 9.3 19.3 13 6.0 0.2 6.5 4 2 3 7 7 7 0 Protein of unknown function (DUF2379) OrfB_IS605 PF01385.19 PVD18232.1 - 1.3 9.3 23.4 1.3 9.3 0.4 5.7 4 1 1 5 5 5 0 Probable transposase ATP-synt_DE PF00401.20 PVD18232.1 - 1.6 9.1 7.0 2.3 8.6 0.9 4.3 5 1 0 5 5 5 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Syntaxin-6_N PF09177.11 PVD18233.1 - 0.1 13.1 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Peptidase_M13_N PF05649.13 PVD18235.1 - 9.9e-17 61.7 1.6 9.9e-11 41.9 0.3 2.1 1 1 1 2 2 2 2 Peptidase family M13 API5 PF05918.11 PVD18235.1 - 0.029 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fibrinogen_C PF00147.18 PVD18236.1 - 1.9e-07 31.1 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain RNA_pol_A_CTD PF03118.15 PVD18236.1 - 0.0015 18.3 0.2 0.002 17.8 0.2 1.1 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNase_H PF00075.24 PVD18237.1 - 5.7e-07 29.8 0.0 1.6e-06 28.4 0.0 1.7 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.6 PVD18237.1 - 0.19 12.5 1.2 0.3 11.8 0.3 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase XRCC4 PF06632.12 PVD18238.1 - 3e-39 134.8 5.6 3e-39 134.8 5.6 1.5 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 MAM PF00629.23 PVD18238.1 - 2.3e-19 69.9 0.7 1.2e-18 67.5 0.2 2.5 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Peptidase_S24 PF00717.23 PVD18238.1 - 7.6e-11 41.8 0.1 1.6e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like Leu_zip PF15294.6 PVD18238.1 - 0.002 17.7 2.5 0.0034 16.9 2.5 1.3 1 0 0 1 1 1 1 Leucine zipper Peptidase_S26 PF10502.9 PVD18238.1 - 0.014 15.2 0.1 0.43 10.4 0.0 2.4 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 DUF4164 PF13747.6 PVD18238.1 - 0.025 14.9 0.6 0.061 13.6 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Med21 PF11221.8 PVD18238.1 - 0.11 12.8 1.6 0.33 11.2 1.6 1.8 1 0 0 1 1 1 0 Subunit 21 of Mediator complex ZapB PF06005.12 PVD18238.1 - 1.9 9.0 6.6 1.4 9.4 4.2 1.9 1 1 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 PVD18238.1 - 3.1 8.0 7.2 2.2 8.5 4.7 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 EF-hand_1 PF00036.32 PVD18240.1 - 2.7e-18 64.1 18.3 0.0007 19.0 0.1 6.1 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 PVD18240.1 - 5.7e-18 65.1 21.7 1.6e-08 34.8 5.5 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD18240.1 - 3.8e-16 57.6 14.5 0.018 14.9 0.1 5.6 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 PVD18240.1 - 3e-11 42.3 23.3 0.0025 17.2 0.2 5.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 PVD18240.1 - 6.1e-07 29.2 16.8 0.016 15.1 0.0 5.7 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_10 PF14788.6 PVD18240.1 - 0.0074 16.1 1.4 2.6 8.0 0.0 3.2 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD18240.1 - 0.018 15.4 14.8 0.68 10.3 6.3 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF327 PF03885.13 PVD18240.1 - 0.063 13.3 0.6 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) OTU PF02338.19 PVD18241.1 - 4.9e-11 43.2 0.0 1.3e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease IPP-2 PF04979.14 PVD18242.1 - 5.4e-35 121.0 10.7 7.3e-35 120.6 10.7 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Tfb4 PF03850.14 PVD18242.1 - 0.073 12.6 1.5 0.094 12.2 1.5 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 YTH PF04146.15 PVD18244.1 - 5e-23 81.9 0.0 9.2e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain NTP_transf_2 PF01909.23 PVD18244.1 - 0.00018 21.7 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain RlaP PF10127.9 PVD18244.1 - 0.00077 19.1 0.1 0.015 14.9 0.0 2.7 2 1 1 3 3 3 1 RNA repair pathway DNA polymerase beta family Polbeta PF18765.1 PVD18244.1 - 0.026 14.6 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase TBCC PF07986.12 PVD18245.1 - 5.4e-42 142.3 10.4 5.6e-42 142.3 6.5 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 PVD18245.1 - 5.7e-05 22.8 1.0 0.00012 21.7 1.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal OB_NTP_bind PF07717.16 PVD18246.1 - 1.2e-15 57.6 0.1 3.1e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD18246.1 - 1.2e-11 44.9 0.0 2.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 PVD18246.1 - 5.8e-11 42.6 0.0 1.4e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) MAP70 PF07058.11 PVD18246.1 - 0.11 11.2 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 dsrm PF00035.26 PVD18247.1 - 2.6e-14 53.7 0.6 1.3e-08 35.4 0.1 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 PVD18247.1 - 1.6e-07 31.3 0.1 6.8e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ATPase PF06745.13 PVD18247.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_11 PF13086.6 PVD18247.1 - 0.011 15.6 0.9 0.1 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 PVD18247.1 - 0.018 15.3 0.1 0.067 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PVD18247.1 - 0.021 15.2 0.1 0.069 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Dicer_dimer PF03368.14 PVD18247.1 - 0.04 14.1 0.1 0.49 10.6 0.0 2.5 2 0 0 2 2 2 0 Dicer dimerisation domain fn3 PF00041.21 PVD18248.1 - 1.1e-07 32.1 23.6 8.2 6.9 0.0 11.4 10 2 0 10 10 10 4 Fibronectin type III domain PAN_1 PF00024.26 PVD18248.1 - 2.7e-05 24.0 0.1 8.7e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 PAN domain zf-UBP_var PF17807.1 PVD18248.1 - 2.1 8.1 5.9 8.6 6.2 5.9 2.0 1 0 0 1 1 1 0 Variant UBP zinc finger VWD PF00094.25 PVD18249.1 - 7.2e-08 32.9 0.1 1.7e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain Phasin PF05597.11 PVD18252.1 - 0.025 14.6 0.7 0.03 14.3 0.7 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AAA_16 PF13191.6 PVD18253.1 - 0.00081 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 PVD18253.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PVD18253.1 - 0.0041 17.4 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD18253.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD18253.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 PVD18253.1 - 0.045 12.4 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA PF00004.29 PVD18253.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PVD18253.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD18253.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 PVD18253.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 PVD18253.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Helicase PIF1 PF05970.14 PVD18253.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase VWD PF00094.25 PVD18254.1 - 4.5e-09 36.8 0.0 9.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18254.1 - 0.015 15.7 10.4 0.015 15.7 10.4 3.4 4 0 0 4 4 4 0 EGF-like domain CUB PF00431.20 PVD18255.1 - 4.3e-10 39.9 0.0 4.8e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 CUB domain LRR_4 PF12799.7 PVD18255.1 - 4.8e-09 36.3 13.8 1.4e-06 28.5 5.6 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD18255.1 - 4.4e-08 32.8 6.3 1.3e-07 31.3 6.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat Lectin_C PF00059.21 PVD18255.1 - 3.8e-06 27.6 0.0 9.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD18255.1 - 0.024 14.8 2.7 0.024 14.8 2.7 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A NDC10_II PF16787.5 PVD18255.1 - 0.028 13.5 0.3 0.046 12.8 0.3 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CUB_2 PF02408.20 PVD18255.1 - 0.035 13.9 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 CUB-like domain LRR_1 PF00560.33 PVD18255.1 - 0.042 14.4 5.9 22 6.1 0.3 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat C4 PF01413.19 PVD18256.1 - 3e-77 256.2 0.7 2e-39 134.4 0.1 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 PVD18256.1 - 3.4e-35 119.6 82.3 1.2e-07 31.3 24.8 4.9 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Ldl_recept_a PF00057.18 PVD18257.1 - 0.0018 18.4 1.3 0.0018 18.4 1.3 1.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TIM PF00121.18 PVD18260.1 - 0.17 11.3 0.0 0.44 9.9 0.0 1.6 1 1 1 2 2 2 0 Triosephosphate isomerase VWD PF00094.25 PVD18262.1 - 0.00012 22.4 0.1 0.00026 21.3 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18262.1 - 0.0018 18.6 39.2 0.013 15.8 10.7 3.7 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 PVD18262.1 - 0.31 11.2 35.5 0.22 11.7 7.1 3.8 3 0 0 3 3 3 0 Laminin EGF domain EGF_Tenascin PF18720.1 PVD18262.1 - 9.3 6.4 24.3 1.5 8.9 6.9 3.1 2 0 0 2 2 2 0 Tenascin EGF domain LRR_4 PF12799.7 PVD18263.1 - 2.8e-12 46.6 8.0 4.3e-07 30.2 4.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD18263.1 - 2.7e-11 43.0 11.1 1.9e-07 30.8 4.7 2.5 2 0 0 2 2 2 2 Leucine rich repeat CUB PF00431.20 PVD18263.1 - 2.2e-10 40.8 0.0 5.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 CUB domain Lectin_C PF00059.21 PVD18263.1 - 2.2e-05 25.1 0.0 5.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD18263.1 - 0.016 15.4 2.0 0.016 15.4 2.0 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A NDC10_II PF16787.5 PVD18263.1 - 0.031 13.3 0.4 0.051 12.6 0.4 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CUB_2 PF02408.20 PVD18263.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 CUB-like domain LRR_1 PF00560.33 PVD18263.1 - 0.42 11.4 10.4 22 6.1 0.3 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD18263.1 - 3.9 7.8 6.8 11 6.3 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat VWD PF00094.25 PVD18264.1 - 1e-26 94.1 0.2 2.5e-08 34.3 0.1 3.8 3 0 0 3 3 3 3 von Willebrand factor type D domain Glyco_transf_7C PF02709.14 PVD18264.1 - 1.4e-05 24.7 0.0 0.76 9.5 0.0 3.5 3 0 0 3 3 3 3 N-terminal domain of galactosyltransferase QueF_N PF14819.6 PVD18264.1 - 0.0081 16.5 0.0 20 5.6 0.0 3.4 3 0 0 3 3 3 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term SBD PF17882.1 PVD18265.1 - 0.032 14.1 0.2 0.099 12.5 0.1 1.8 1 1 0 1 1 1 0 OAA-family lectin sugar binding domain E2F_TDP PF02319.20 PVD18265.1 - 0.042 13.9 1.4 0.087 12.9 1.4 1.7 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain DUF4407 PF14362.6 PVD18265.1 - 1.7 7.9 7.5 2.3 7.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 PVD18265.1 - 1.8 8.6 5.4 2.5 8.2 5.4 1.3 1 0 0 1 1 1 0 DDHD domain Exo_endo_phos_2 PF14529.6 PVD18267.1 - 2.1e-09 37.2 0.4 3.7e-09 36.5 0.2 1.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD18267.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YvrJ PF12841.7 PVD18268.1 - 0.15 11.6 0.5 0.36 10.4 0.5 1.7 1 0 0 1 1 1 0 YvrJ protein family Inhibitor_I53 PF11714.8 PVD18269.1 - 0.014 15.6 1.8 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 Thrombin inhibitor Madanin US10 PF17617.2 PVD18269.1 - 0.19 11.8 0.0 9.4 6.3 0.0 2.0 1 1 1 2 2 2 0 Viral unique short region 10 Antimicrobial_9 PF08104.11 PVD18269.1 - 8.3 6.5 7.0 10 6.2 0.1 3.2 3 0 0 3 3 3 0 Ponericin L family PNTB_4TM PF12769.7 PVD18270.1 - 0.021 15.3 0.9 2.9 8.4 0.3 2.7 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Rhomboid PF01694.22 PVD18271.1 - 7.6e-23 81.2 11.9 1.2e-22 80.5 11.9 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 PVD18271.1 - 0.026 15.1 3.0 0.026 15.1 3.0 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Pneumo_matrix PF03393.16 PVD18271.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein NACHT_N PF17100.5 PVD18271.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Potassium_chann PF11404.8 PVD18271.1 - 5.1 7.0 5.4 3.1 7.7 1.7 2.3 2 0 0 2 2 2 0 Potassium voltage-gated channel Peptidase_C54 PF03416.19 PVD18272.1 - 2.4e-100 335.5 0.1 2.8e-100 335.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase family C54 DUF1794 PF08768.11 PVD18273.1 - 1.1e-40 139.0 0.0 1.3e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) 4HBT PF03061.22 PVD18274.1 - 8.1e-09 35.7 0.0 0.0027 18.0 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Cu-oxidase_2 PF07731.14 PVD18275.1 - 8.5e-21 74.1 1.0 5.3e-19 68.3 1.9 2.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 PVD18275.1 - 1.7e-15 57.5 0.0 5.5e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Fibrinogen_C PF00147.18 PVD18276.1 - 8.1e-120 398.5 31.3 7e-30 104.5 0.3 8.6 5 3 3 8 8 8 7 Fibrinogen beta and gamma chains, C-terminal globular domain Cu-oxidase_3 PF07732.15 PVD18276.1 - 5.1e-33 113.6 0.2 1.7e-32 111.9 0.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase V-set PF07686.17 PVD18276.1 - 6.2e-23 81.1 0.3 3.5e-05 23.9 0.0 6.7 6 0 0 6 6 5 4 Immunoglobulin V-set domain I-set PF07679.16 PVD18276.1 - 1.6e-12 47.3 0.4 1.6 8.8 0.0 8.1 10 0 0 10 10 7 2 Immunoglobulin I-set domain Herpes_gI PF01688.17 PVD18276.1 - 3.5e-06 27.0 0.0 0.81 9.6 0.0 5.1 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein I Cu-oxidase_2 PF07731.14 PVD18276.1 - 7.9e-05 22.4 0.9 0.00049 19.8 0.9 2.2 1 1 0 1 1 1 1 Multicopper oxidase ig PF00047.25 PVD18276.1 - 0.00013 22.1 12.6 1.6 8.9 0.0 8.0 9 0 0 9 9 8 1 Immunoglobulin domain Baculo_gp64 PF03273.13 PVD18276.1 - 0.00027 19.9 3.7 3.2 6.5 0.1 3.8 4 0 0 4 4 4 3 Baculovirus gp64 envelope glycoprotein family ZapB PF06005.12 PVD18276.1 - 0.0012 19.2 34.3 0.34 11.4 2.8 4.3 4 0 0 4 4 4 3 Cell division protein ZapB DUF3565 PF12088.8 PVD18276.1 - 0.0085 16.0 5.3 1.7 8.6 0.2 3.9 4 0 0 4 4 3 1 Protein of unknown function (DUF3565) Ig_6 PF18452.1 PVD18276.1 - 0.0095 15.5 0.2 7.7 6.2 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin domain YabA PF06156.13 PVD18276.1 - 0.013 16.1 25.5 0.26 11.9 0.9 4.4 4 0 0 4 4 4 0 Initiation control protein YabA HTH_30 PF13556.6 PVD18276.1 - 0.033 14.0 0.4 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain bZIP_1 PF00170.21 PVD18276.1 - 0.039 14.1 35.6 0.31 11.2 4.2 4.3 4 0 0 4 4 4 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 PVD18276.1 - 0.098 12.9 28.3 0.054 13.7 1.6 4.2 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 PVD18276.1 - 0.18 12.1 30.0 0.088 13.0 1.3 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper EMA PF02488.15 PVD18276.1 - 0.22 11.2 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 Merozoite Antigen Wtap PF17098.5 PVD18276.1 - 0.25 11.3 23.6 0.019 14.9 1.5 3.8 4 0 0 4 4 4 0 WTAP/Mum2p family CENP-F_N PF10481.9 PVD18276.1 - 0.35 10.5 9.3 2.4 7.7 0.3 3.2 3 0 0 3 3 3 0 Cenp-F N-terminal domain JIP_LZII PF16471.5 PVD18276.1 - 2.7 8.2 28.5 0.33 11.1 1.6 4.4 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 PVD18276.1 - 2.8 8.2 30.9 0.21 11.8 1.2 4.3 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 MgrB PF13998.6 PVD18276.1 - 5.7 6.9 5.1 1e+02 2.9 0.1 3.5 3 0 0 3 3 3 0 MgrB protein Noelin-1 PF12308.8 PVD18276.1 - 6.5 6.8 14.8 4.1 7.4 0.2 4.5 4 0 0 4 4 4 0 Neurogenesis glycoprotein DivIVA PF05103.13 PVD18276.1 - 7 6.7 21.1 0.77 9.8 0.6 4.0 4 0 0 4 4 4 0 DivIVA protein Fibrinogen_C PF00147.18 PVD18277.1 - 1.4e-34 119.8 3.7 2.6e-30 105.9 0.4 2.3 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain V-set PF07686.17 PVD18277.1 - 2.6e-13 50.1 1.2 1.5e-05 25.1 0.0 3.9 4 1 1 5 5 5 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD18277.1 - 3.4e-08 34.0 6.7 0.27 11.9 0.1 5.1 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD18277.1 - 1e-07 31.9 0.7 0.19 11.8 0.0 5.0 6 0 0 6 6 6 2 Immunoglobulin I-set domain Invasin_D3 PF09134.10 PVD18277.1 - 1.1e-05 25.7 0.2 0.074 13.4 0.0 3.4 3 0 0 3 3 3 2 Invasin, domain 3 Ig_2 PF13895.6 PVD18277.1 - 0.0074 16.6 7.9 0.061 13.7 0.1 4.3 4 2 1 5 5 5 1 Immunoglobulin domain Herpes_gI PF01688.17 PVD18277.1 - 0.0085 16.0 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein I Jnk-SapK_ap_N PF09744.9 PVD18277.1 - 0.016 15.5 0.6 0.023 14.9 0.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 PVD18277.1 - 0.02 14.9 1.4 0.031 14.3 1.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 PVD18277.1 - 0.047 13.9 3.0 0.078 13.2 3.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 PVD18277.1 - 0.056 13.6 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Big_3_2 PF12245.8 PVD18277.1 - 0.058 13.7 0.1 5.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain UPF0449 PF15136.6 PVD18277.1 - 0.061 13.8 1.2 0.12 12.9 1.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Pur_ac_phosph_N PF16656.5 PVD18277.1 - 0.97 10.0 4.2 7 7.3 0.1 3.8 5 0 0 5 5 4 0 Purple acid Phosphatase, N-terminal domain HALZ PF02183.18 PVD18278.1 - 1.3e-08 34.9 33.4 0.00073 19.7 6.4 4.9 1 1 5 6 6 6 5 Homeobox associated leucine zipper V-set PF07686.17 PVD18278.1 - 2.8e-05 24.3 3.2 9.6e-05 22.5 0.0 2.9 4 0 0 4 4 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD18278.1 - 0.00059 20.4 3.3 1.3 9.7 0.0 3.4 3 2 0 3 3 2 2 Immunoglobulin domain ZapB PF06005.12 PVD18278.1 - 0.00061 20.2 41.0 0.093 13.2 16.4 2.7 2 1 1 3 3 3 2 Cell division protein ZapB Ig_2 PF13895.6 PVD18278.1 - 0.0046 17.3 3.8 0.0077 16.5 0.1 3.1 3 2 1 4 4 2 1 Immunoglobulin domain I-set PF07679.16 PVD18278.1 - 0.0048 16.9 0.2 0.62 10.2 0.0 3.4 2 2 0 2 2 2 1 Immunoglobulin I-set domain YabA PF06156.13 PVD18278.1 - 0.013 16.1 30.0 0.48 11.1 12.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 PVD18278.1 - 0.019 14.8 38.0 0.93 9.3 37.3 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 PVD18278.1 - 0.02 15.1 26.8 0.79 9.9 4.0 3.4 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PVD18278.1 - 0.024 14.7 28.8 0.082 13.0 5.5 4.3 1 1 4 5 5 5 0 bZIP transcription factor DivIC PF04977.15 PVD18278.1 - 0.028 14.2 36.5 0.045 13.5 8.1 4.4 2 1 3 5 5 4 0 Septum formation initiator CENP-F_leu_zip PF10473.9 PVD18278.1 - 0.061 13.3 34.7 0.5 10.4 25.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 PVD18278.1 - 0.065 14.0 28.3 0.5 11.1 16.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TSC22 PF01166.18 PVD18278.1 - 0.091 13.1 29.9 0.35 11.2 4.3 4.8 1 1 4 5 5 5 0 TSC-22/dip/bun family Herpes_gI PF01688.17 PVD18278.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I HAP1_N PF04849.13 PVD18278.1 - 0.13 11.4 29.1 0.19 10.9 29.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FPP PF05911.11 PVD18278.1 - 0.29 9.3 26.9 0.37 8.9 26.9 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil HMMR_N PF15905.5 PVD18278.1 - 0.35 10.3 33.7 0.47 9.9 33.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4686 PF15742.5 PVD18278.1 - 0.35 10.0 45.1 0.51 9.4 34.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) M PF02370.16 PVD18278.1 - 0.42 11.3 38.2 0.92 10.3 0.2 6.8 6 1 1 7 7 6 0 M protein repeat LAGLIDADG_3 PF14528.6 PVD18278.1 - 0.42 10.9 5.2 0.29 11.5 0.6 2.6 1 1 2 3 3 3 0 LAGLIDADG-like domain GCN5L1 PF06320.13 PVD18278.1 - 0.75 10.0 26.6 1.1 9.4 8.2 3.2 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Syntaxin-6_N PF09177.11 PVD18278.1 - 1.1 9.9 19.8 6.7 7.3 10.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 PVD18278.1 - 1.5 9.4 36.7 0.34 11.4 27.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region NRBF2 PF08961.10 PVD18278.1 - 1.7 8.2 19.6 1 8.9 3.1 3.0 1 1 3 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1664 PF07889.12 PVD18278.1 - 1.8 8.6 24.1 0.85 9.7 13.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pyr_redox PF00070.27 PVD18278.1 - 2.5 8.7 5.4 63 4.2 0.2 3.8 2 1 2 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase PikAIV_N PF18605.1 PVD18278.1 - 3.1 7.5 6.7 17 5.1 0.8 3.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Spc7 PF08317.11 PVD18278.1 - 3.3 6.5 33.0 19 4.0 32.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.13 PVD18278.1 - 3.8 7.6 35.9 1.4 9.0 15.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 PVD18278.1 - 3.9 6.9 24.0 6 6.3 24.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40_alt PF14077.6 PVD18278.1 - 5.8 6.9 8.1 18 5.3 0.1 3.3 1 1 3 4 4 3 0 Alternative WD40 repeat motif DUF4559 PF15112.6 PVD18278.1 - 5.9 6.5 24.9 8.4 6.0 24.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FUSC PF04632.12 PVD18278.1 - 5.9 5.3 7.4 8.1 4.8 7.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 PVD18278.1 - 6.1 7.2 24.5 2.3 8.6 10.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YscO PF07321.12 PVD18278.1 - 6.1 6.8 30.4 7.2 6.6 8.0 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO HSP70 PF00012.20 PVD18278.1 - 6.5 4.8 16.8 8.5 4.4 16.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Golgin_A5 PF09787.9 PVD18278.1 - 7.6 5.9 34.5 11 5.4 34.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 PVD18278.1 - 7.6 4.3 22.2 12 3.7 22.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP PF04728.13 PVD18278.1 - 8.6 6.8 26.8 3.4 8.1 3.0 4.6 1 1 4 5 5 5 0 Lipoprotein leucine-zipper Spc24 PF08286.11 PVD18278.1 - 9.2 6.6 32.8 1.4 9.2 4.7 3.4 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 PVD18278.1 - 9.6 5.7 31.0 20 4.7 31.0 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fibrinogen_C PF00147.18 PVD18279.1 - 9.5e-24 84.4 2.8 2.5e-20 73.3 0.3 2.2 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain E2F_CC-MB PF16421.5 PVD18279.1 - 0.098 13.0 0.1 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Astacin PF01400.24 PVD18280.1 - 3.1e-37 128.0 0.0 1.1e-34 119.7 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 PVD18280.1 - 0.00012 22.0 0.8 0.0055 16.6 0.4 2.4 1 1 1 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 PVD18280.1 - 0.0036 16.3 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M64 PF09471.10 PVD18280.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M43 PF05572.13 PVD18280.1 - 0.2 11.6 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A GFO_IDH_MocA PF01408.22 PVD18281.1 - 2.7e-15 57.2 0.0 1.9e-14 54.5 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD18281.1 - 0.00069 19.6 0.0 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 PVD18281.1 - 0.0022 18.1 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 PVD18281.1 - 0.012 15.8 0.0 0.11 12.8 0.0 2.3 2 1 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PVD18281.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 PVD18281.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PVD18281.1 - 0.051 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 PVD18281.1 - 0.065 13.9 0.0 0.31 11.7 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain zf-CCCH PF00642.24 PVD18282.1 - 5e-08 32.7 2.2 9.4e-08 31.8 2.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD18282.1 - 0.00015 21.7 2.0 0.00028 20.8 2.0 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PVD18282.1 - 0.002 17.9 3.2 0.0037 17.0 3.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Pyr_redox_2 PF07992.14 PVD18283.1 - 7e-67 225.7 1.1 9.4e-67 225.3 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PVD18283.1 - 9.7e-33 112.7 0.1 2.3e-32 111.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PVD18283.1 - 8e-23 80.8 2.5 8.9e-20 71.0 0.9 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD18283.1 - 4.5e-20 72.1 0.9 8e-20 71.3 0.9 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD18283.1 - 6.7e-07 28.4 3.3 0.022 13.5 0.1 3.2 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 PVD18283.1 - 7.6e-06 25.5 0.2 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD18283.1 - 6.6e-05 22.2 0.1 0.0027 16.8 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 PVD18283.1 - 0.00016 20.9 0.1 0.00081 18.6 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 PVD18283.1 - 0.0044 16.4 1.8 0.56 9.5 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 PVD18283.1 - 0.019 14.4 1.5 3.8 6.8 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 PVD18283.1 - 0.03 14.6 0.2 0.074 13.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD18283.1 - 0.03 13.9 14.0 0.13 11.8 1.6 3.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PVD18283.1 - 0.096 12.7 1.6 9.6 6.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 PVD18283.1 - 0.13 12.1 3.7 0.77 9.6 0.1 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 PVD18283.1 - 0.19 11.0 0.1 0.19 11.0 0.1 2.0 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.6 PVD18283.1 - 0.3 11.6 2.8 6.6 7.2 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 PVD18283.1 - 1.5 7.8 7.6 7.1 5.6 2.4 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PVD18283.1 - 1.8 7.8 3.8 1.3 8.2 0.3 2.3 2 1 1 3 3 3 0 FAD binding domain Lipase PF00151.19 PVD18285.1 - 1.2e-80 271.3 0.0 1.6e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 PVD18285.1 - 1e-05 26.3 0.5 1.5e-05 25.7 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 PVD18285.1 - 6.3e-05 22.6 0.1 0.00015 21.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 PVD18285.1 - 0.0063 16.2 0.2 0.014 15.0 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold SAT PF16073.5 PVD18285.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis LIDHydrolase PF10230.9 PVD18285.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SBF PF01758.16 PVD18286.1 - 9.4e-08 31.9 4.6 8.3e-06 25.6 2.7 2.6 2 0 0 2 2 2 2 Sodium Bile acid symporter family Cyt_bd_oxida_I PF01654.17 PVD18286.1 - 0.0088 14.7 1.7 0.017 13.7 1.7 1.5 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I SH2 PF00017.24 PVD18286.1 - 0.018 15.2 0.6 7.8 6.7 0.0 3.2 3 0 0 3 3 3 0 SH2 domain AAA_12 PF13087.6 PVD18287.1 - 3.1e-31 108.6 0.0 6.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD18287.1 - 9.3e-25 87.9 1.1 9.3e-25 87.9 1.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD18287.1 - 6.7e-10 39.5 0.2 1.7e-08 34.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD18287.1 - 9e-08 32.1 0.0 0.00023 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 PVD18287.1 - 0.0004 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PVD18287.1 - 0.0013 18.1 0.1 0.0038 16.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 PVD18287.1 - 0.0028 17.9 0.2 0.26 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 PVD18287.1 - 0.016 14.8 1.7 0.094 12.2 0.1 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 PVD18287.1 - 0.096 12.4 0.2 2.6 7.8 0.0 3.4 5 0 0 5 5 5 0 DEAD/DEAH box helicase AAA_25 PF13481.6 PVD18287.1 - 0.12 12.0 0.2 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_13 PF17958.1 PVD18289.1 - 8.2e-28 96.1 0.0 3e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PVD18289.1 - 2.9e-21 75.7 2.0 2.9e-21 75.7 2.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD18289.1 - 1.2e-05 24.6 0.2 0.00021 20.6 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 PVD18289.1 - 4.5e-05 22.7 1.0 0.012 15.1 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 PVD18289.1 - 5.5e-05 22.8 0.2 0.015 15.2 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain MAP65_ASE1 PF03999.12 PVD18289.1 - 0.0062 15.3 11.5 0.0089 14.8 11.5 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4187 PF13821.6 PVD18289.1 - 0.051 13.4 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_8 PF13833.6 PVD18289.1 - 0.06 13.2 0.0 0.32 10.9 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD18289.1 - 0.17 12.2 4.0 2.9 8.2 0.3 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ANAPC1 PF12859.7 PVD18292.1 - 0.18 12.4 1.2 0.39 11.3 1.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 zf-C2H2_4 PF13894.6 PVD18293.1 - 2.6e-19 68.2 67.0 0.002 18.8 0.4 8.7 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD18293.1 - 3.3e-17 61.9 75.1 0.00075 19.8 3.9 8.6 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD18293.1 - 4.4e-14 52.2 62.9 0.0004 20.7 0.5 9.4 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD18293.1 - 0.0013 18.7 1.4 0.057 13.4 0.0 8.0 8 0 0 8 8 8 4 C2H2-type zinc finger CpXC PF14353.6 PVD18293.1 - 0.0036 17.3 20.6 0.087 12.9 0.0 5.2 4 1 1 5 5 5 2 CpXC protein ADK_lid PF05191.14 PVD18293.1 - 0.12 12.3 13.7 2.5 8.2 3.7 4.0 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 PVD18293.1 - 1.6 9.1 0.0 1.6 9.1 0.0 7.8 8 1 1 9 9 9 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 PVD18293.1 - 2.7 8.8 25.2 2.2 9.1 2.1 4.9 4 1 1 5 5 5 0 zinc-ribbon family zf-C2HE PF16278.5 PVD18293.1 - 8.4 6.9 37.3 0.52 10.8 0.2 6.6 5 2 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger 7TM_GPCR_Srw PF10324.9 PVD18294.1 - 1.4e-08 34.5 4.9 1.8e-08 34.1 4.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD18294.1 - 0.1 11.9 5.1 0.092 12.1 4.2 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD18295.1 - 7.1e-07 29.1 16.2 0.0031 17.2 10.9 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD18295.1 - 1.4e-05 24.6 4.1 1.4e-05 24.6 4.1 2.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD18295.1 - 0.00025 20.5 11.3 0.01 15.3 6.0 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.21 PVD18295.1 - 0.00049 19.9 17.3 0.056 13.1 8.0 2.9 3 0 0 3 3 3 2 Srg family chemoreceptor OprD PF03573.13 PVD18295.1 - 0.0041 16.2 0.4 1.4 7.9 0.0 2.4 3 0 0 3 3 3 2 outer membrane porin, OprD family FAIM1 PF06905.13 PVD18296.1 - 5e-16 58.9 0.0 6.7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF4996 PF16387.5 PVD18296.1 - 0.029 14.8 0.0 0.039 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function PSK_trans_fac PF07704.11 PVD18296.1 - 0.085 13.6 2.9 0.14 12.9 2.9 1.3 1 0 0 1 1 1 0 Rv0623-like transcription factor DNA_photolyase PF00875.18 PVD18297.1 - 9.8e-29 100.5 0.0 1.9e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase WIYLD PF10440.9 PVD18297.1 - 0.12 12.2 0.0 8 6.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain CAP_GLY PF01302.25 PVD18298.1 - 3.5e-20 71.8 0.9 6.2e-20 71.0 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain TAF6_C PF07571.13 PVD18299.1 - 2e-29 101.8 0.1 6e-29 100.2 0.1 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PVD18299.1 - 3.6e-23 81.5 0.1 8.7e-23 80.3 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 PVD18299.1 - 0.009 16.4 0.8 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD18299.1 - 0.018 15.3 0.1 0.041 14.2 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 PVD18299.1 - 0.13 12.3 1.2 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit MbeB_N PF04837.12 PVD18299.1 - 0.22 11.8 1.2 3.5 8.0 0.3 2.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DSBA PF01323.20 PVD18300.1 - 5.1e-34 117.7 0.0 5.9e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 PVD18300.1 - 3.2e-06 27.4 0.0 0.00019 21.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin LPD7 PF18821.1 PVD18300.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 7 Pkinase PF00069.25 PVD18302.1 - 1.5e-65 221.2 0.0 3.2e-65 220.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.21 PVD18302.1 - 1.8e-59 200.5 0.0 3.2e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Pkinase_Tyr PF07714.17 PVD18302.1 - 7.1e-29 100.9 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.24 PVD18302.1 - 2.3e-15 56.7 0.1 4.4e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 PVD18302.1 - 4.4e-09 35.9 0.0 1.2e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD18302.1 - 4.1e-07 29.5 2.2 1.7e-06 27.5 2.2 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD18302.1 - 9.3e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain L27 PF02828.16 PVD18302.1 - 1.9e-05 24.3 15.3 0.00074 19.2 0.4 4.2 5 0 0 5 5 5 2 L27 domain PDZ_6 PF17820.1 PVD18302.1 - 0.0091 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 PVD18302.1 - 0.024 14.0 0.0 0.064 12.6 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_4 PF17816.1 PVD18302.1 - 0.026 14.9 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 PVD18302.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Exo_endo_phos PF03372.23 PVD18303.1 - 0.056 13.0 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 PVD18306.1 - 2.1e-14 53.1 0.0 3.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Astacin PF01400.24 PVD18307.1 - 4.7e-109 362.3 4.3 2.6e-54 183.8 0.3 2.5 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) ShK PF01549.24 PVD18307.1 - 7.3e-45 151.2 161.2 6.7e-08 32.9 5.6 11.0 10 1 1 11 11 11 9 ShK domain-like Peptidase_M66 PF10462.9 PVD18307.1 - 4e-05 22.7 0.5 0.075 12.0 0.1 2.4 2 0 0 2 2 2 2 Peptidase M66 Peptidase_M10 PF00413.24 PVD18307.1 - 0.00018 21.4 5.7 2.3 8.1 0.0 4.1 3 1 1 4 4 4 2 Matrixin Reprolysin_4 PF13583.6 PVD18307.1 - 0.011 15.4 0.2 5.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD18307.1 - 0.043 14.3 0.6 16 6.1 0.1 2.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like YqzE PF14038.6 PVD18307.1 - 0.56 10.2 2.0 1.5 8.9 0.4 2.3 2 0 0 2 2 2 0 YqzE-like protein DUF4953 PF16313.5 PVD18307.1 - 1.3 8.2 5.1 9.4 5.3 0.3 2.4 2 0 0 2 2 2 0 Met-zincin zf-CCCH PF00642.24 PVD18307.1 - 1.3 9.0 21.8 4.3 7.4 0.2 7.0 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1126 PF06565.12 PVD18308.1 - 1.8e-185 603.0 13.7 1.3e-32 111.8 0.0 6.8 6 0 0 6 6 6 6 DUF1126 PH-like domain EF-hand_7 PF13499.6 PVD18308.1 - 9.4e-12 45.2 1.0 0.033 14.6 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD18308.1 - 1.3e-08 33.7 0.0 2.9 7.7 0.0 6.6 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 PVD18308.1 - 2.4e-07 30.1 0.0 0.69 10.0 0.0 6.0 6 0 0 6 6 6 1 EF-hand domain EF-hand_11 PF08976.11 PVD18308.1 - 0.0086 16.9 0.0 1.1 10.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain FUSC-like PF12805.7 PVD18308.1 - 0.89 8.6 3.7 1.7 7.7 3.7 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CUE PF02845.16 PVD18309.1 - 0.03 14.1 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 CUE domain FAM178 PF14816.6 PVD18309.1 - 9.9 5.0 7.9 15 4.4 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Bcl-2 PF00452.19 PVD18310.1 - 2.9e-18 66.4 0.2 4e-18 65.9 0.2 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family SpoIISA_toxin PF14171.6 PVD18312.1 - 0.031 14.0 0.4 0.06 13.0 0.4 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system zf-C3H2C3 PF17122.5 PVD18312.1 - 0.34 11.0 1.5 3.7 7.7 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger DUF1664 PF07889.12 PVD18312.1 - 4.9 7.2 5.6 1.2 9.2 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) F420_oxidored PF03807.17 PVD18313.1 - 1.1e-13 51.5 0.0 2.7e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 PVD18313.1 - 8e-11 42.1 4.2 8e-11 42.1 4.2 2.4 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 PVD18313.1 - 5.6e-08 33.1 0.0 3.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 PVD18313.1 - 4.3e-07 30.1 0.1 9.7e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 PVD18313.1 - 6e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PVD18313.1 - 0.0004 20.4 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 PVD18313.1 - 0.0015 18.9 0.0 0.02 15.3 0.0 2.3 1 1 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 PVD18313.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PVD18313.1 - 0.0059 17.0 0.0 0.015 15.7 0.0 1.7 2 0 0 2 2 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 PVD18313.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 PVD18313.1 - 0.015 15.8 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 PVD18313.1 - 0.018 15.3 0.1 3.4 7.9 0.0 2.5 1 1 1 2 2 2 0 TrkA-N domain IlvN PF07991.12 PVD18313.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF2613 PF11021.8 PVD18313.1 - 0.71 10.0 4.7 1.6 8.9 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Papilloma_E5A PF05776.12 PVD18313.1 - 4 7.9 8.1 0.11 12.9 0.6 2.2 2 0 0 2 2 1 0 Papillomavirus E5A protein CENP-I PF07778.11 PVD18314.1 - 7.3e-67 226.2 7.2 1.4e-34 119.8 3.3 2.2 2 0 0 2 2 2 2 Mis6 MFS_1 PF07690.16 PVD18315.1 - 9.1e-32 110.3 36.5 4.5e-18 65.3 16.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PhoLip_ATPase_C PF16212.5 PVD18316.1 - 5.8e-33 114.7 10.3 5.8e-33 114.7 10.3 2.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PVD18316.1 - 4.5e-20 71.1 0.8 4.5e-20 71.1 0.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PVD18316.1 - 3.5e-12 47.1 0.0 8.2e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PVD18316.1 - 2.9e-10 40.1 0.3 8.3e-09 35.4 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PVD18316.1 - 1.9e-08 34.1 0.0 9e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PVD18316.1 - 0.0013 18.5 0.1 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3612 PF12268.8 PVD18316.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) GCP_N_terminal PF17681.1 PVD18317.1 - 8.1e-90 301.5 0.3 2.4e-89 300.0 0.1 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 PVD18317.1 - 3.8e-84 282.8 9.7 8.3e-84 281.7 7.9 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Glyco_transf_8 PF01501.20 PVD18318.1 - 3.6e-18 66.1 0.9 3.2e-16 59.7 0.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PVD18318.1 - 0.0024 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Sua5_yciO_yrdC PF01300.18 PVD18318.1 - 1.5 8.3 6.5 37 3.8 0.1 3.4 1 1 2 3 3 3 0 Telomere recombination IFT57 PF10498.9 PVD18319.1 - 0.0051 15.8 9.7 0.0051 15.8 9.7 2.2 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 PVD18319.1 - 0.023 15.1 6.6 1.4 9.5 0.6 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Lip_prot_lig_C PF10437.9 PVD18319.1 - 0.085 12.9 0.7 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Myosin_tail_1 PF01576.19 PVD18319.1 - 0.11 10.3 39.6 0.048 11.5 36.4 1.7 1 1 1 2 2 2 0 Myosin tail Vip3A_N PF12495.8 PVD18319.1 - 0.2 11.6 1.4 0.17 11.7 0.2 1.6 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal EF-hand_2 PF09068.11 PVD18319.1 - 0.28 11.3 3.8 0.29 11.3 0.8 2.2 1 1 0 2 2 2 0 EF hand Q_salvage PF10343.9 PVD18319.1 - 1.4 8.4 10.1 0.052 13.1 1.5 2.2 1 1 0 2 2 2 0 Potential Queuosine, Q, salvage protein family TSC22 PF01166.18 PVD18319.1 - 1.5 9.2 12.0 0.11 12.8 2.3 3.8 2 2 2 4 4 4 0 TSC-22/dip/bun family Cauli_AT PF03233.13 PVD18319.1 - 3.1 7.7 20.1 0.34 10.8 2.2 3.2 1 1 2 3 3 3 0 Aphid transmission protein CRF PF00473.17 PVD18319.1 - 4.4 7.5 6.6 27 4.9 0.2 2.9 2 0 0 2 2 2 0 Corticotropin-releasing factor family Prominin PF05478.11 PVD18319.1 - 6.3 4.6 15.2 9.1 4.1 15.2 1.3 1 0 0 1 1 1 0 Prominin CREPT PF16566.5 PVD18319.1 - 8.9 6.5 26.4 21 5.2 11.8 3.0 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Nif11 PF07862.11 PVD18320.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Nif11 domain Methyltransf_23 PF13489.6 PVD18320.1 - 0.033 14.0 0.0 0.48 10.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Sec2p PF06428.11 PVD18320.1 - 0.073 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SDF PF00375.18 PVD18321.1 - 1.4e-73 248.2 17.3 6.4e-39 134.1 5.1 2.1 2 0 0 2 2 2 2 Sodium:dicarboxylate symporter family SSF PF00474.17 PVD18322.1 - 3.5e-11 42.6 1.1 5.8e-11 41.9 1.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 PVD18323.1 - 2.6e-22 79.3 18.2 4.3e-22 78.5 18.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Herpes_US9 PF06072.11 PVD18325.1 - 0.13 12.1 0.5 0.24 11.3 0.5 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 UDPGT PF00201.18 PVD18326.1 - 1.2e-23 83.7 0.0 1.7e-23 83.2 0.0 1.2 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD18326.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain bPH_5 PF10882.8 PVD18327.1 - 4.7e-08 33.0 23.1 1e+02 3.1 0.0 16.7 8 6 15 23 23 23 5 Bacterial PH domain HMG_box PF00505.19 PVD18329.1 - 5.4e-12 46.0 3.5 9.2e-11 42.0 0.6 2.5 1 1 1 2 2 2 2 HMG (high mobility group) box SOXp PF12336.8 PVD18329.1 - 4.3e-09 37.3 0.2 2.3e-08 35.0 0.1 2.2 2 0 0 2 2 2 1 SOX transcription factor HMG_box_2 PF09011.10 PVD18329.1 - 0.00069 20.2 0.2 0.0017 18.9 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain P4Ha_N PF08336.11 PVD18329.1 - 0.026 14.6 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA PF00004.29 PVD18331.1 - 8.5e-45 152.4 0.0 3.2e-28 98.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD18331.1 - 5.7e-13 48.4 0.7 4.8e-06 26.3 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PVD18331.1 - 8e-09 36.1 1.0 0.0014 19.1 0.0 3.9 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 PVD18331.1 - 1.6e-06 28.2 0.0 3.2e-05 23.9 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_2 PF07724.14 PVD18331.1 - 2.6e-06 27.6 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 PVD18331.1 - 0.0002 21.9 0.0 0.0002 21.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 PVD18331.1 - 0.00062 19.8 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PVD18331.1 - 0.0011 19.0 0.0 0.0086 16.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PVD18331.1 - 0.002 18.4 0.0 0.059 13.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 PVD18331.1 - 0.0034 17.5 0.0 0.05 13.7 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 PVD18331.1 - 0.0063 16.1 0.3 0.12 11.9 0.2 2.7 2 1 1 3 3 3 1 AAA domain T2SSE PF00437.20 PVD18331.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 PVD18331.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 PVD18331.1 - 0.019 15.3 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 PVD18331.1 - 0.027 14.2 0.0 0.083 12.6 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 PVD18331.1 - 0.035 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_7 PF12775.7 PVD18331.1 - 0.039 13.5 0.0 0.17 11.4 0.0 2.1 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 PVD18331.1 - 0.047 13.3 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.11 PVD18331.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Mg_chelatase PF01078.21 PVD18331.1 - 0.09 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PVD18331.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD18331.1 - 0.18 12.4 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD18331.1 - 0.35 11.4 3.3 0.51 10.9 0.1 2.7 3 1 0 4 4 3 0 ABC transporter PEX-1N PF09262.11 PVD18332.1 - 2.1e-22 79.3 0.1 3.3e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.10 PVD18332.1 - 5.9e-05 23.3 0.0 0.00017 21.8 0.0 1.7 1 1 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal LCM PF04072.14 PVD18333.1 - 5.3e-33 114.6 0.0 1.8e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase EF-hand_7 PF13499.6 PVD18334.1 - 1.3e-08 35.1 1.6 3.5e-08 33.8 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD18334.1 - 1.6e-08 33.8 1.0 3.9e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD18334.1 - 1.2e-06 27.6 1.0 1.2e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PVD18334.1 - 0.00039 20.2 1.9 0.0028 17.5 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD18334.1 - 0.13 11.8 1.0 0.25 10.9 0.0 2.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 PVD18337.1 - 0.013 16.0 0.1 0.028 14.8 0.1 1.6 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_11 PF08976.11 PVD18337.1 - 0.078 13.9 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain DDE_Tnp_4 PF13359.6 PVD18338.1 - 1.9 8.2 5.9 1.1 8.9 0.8 2.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Thymidylate_kin PF02223.17 PVD18339.1 - 2.5e-19 69.7 0.0 3e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase Sec2p PF06428.11 PVD18339.1 - 0.0007 19.5 0.3 0.013 15.4 0.0 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF643 PF04867.12 PVD18339.1 - 0.054 14.1 0.1 0.073 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF643) DUF4793 PF16041.5 PVD18340.1 - 1e-12 48.1 0.2 2.3e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) 4HBT PF03061.22 PVD18341.1 - 3.6e-06 27.2 0.0 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily GPR_Gpa2_C PF11970.8 PVD18342.1 - 6.8e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term IF4E PF01652.18 PVD18343.1 - 1.2e-43 148.7 0.1 2.3e-43 147.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PIP49_C PF12260.8 PVD18343.1 - 5.2e-39 133.8 0.0 7.9e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.25 PVD18344.1 - 2.3e-62 210.8 0.0 3.2e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18344.1 - 2.7e-48 164.5 0.0 4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.22 PVD18344.1 - 2.3e-42 145.5 0.0 1.8e-37 129.5 0.0 2.2 1 1 1 2 2 2 2 CNH domain Pkinase_fungal PF17667.1 PVD18344.1 - 5.9e-06 25.3 0.8 4.1e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 PVD18344.1 - 0.00095 18.6 0.0 0.0039 16.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 PVD18344.1 - 0.0062 16.2 0.1 0.13 11.8 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PVD18344.1 - 0.0091 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD18344.1 - 0.038 13.9 0.1 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PBP1_TM PF14812.6 PVD18344.1 - 1 9.8 4.7 3.1 8.2 4.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C2 PF00648.21 PVD18345.1 - 6.9e-118 393.0 0.2 1.3e-117 392.0 0.2 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD18345.1 - 2e-27 96.2 0.0 3.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 PVD18345.1 - 1.3e-09 38.3 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Arginase PF00491.21 PVD18346.1 - 1.1e-84 284.3 0.0 1.6e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Arginase family 7tm_1 PF00001.21 PVD18346.1 - 8.7e-19 67.9 14.0 8.7e-19 67.9 14.0 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 PVD18346.1 - 0.24 11.4 5.9 0.18 11.7 0.4 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa LRR_8 PF13855.6 PVD18347.1 - 2.3e-14 52.9 8.1 4.7e-11 42.3 3.9 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD18347.1 - 1e-07 32.1 13.3 1.7e-05 25.1 1.3 4.1 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD18347.1 - 5.5e-05 23.2 11.4 0.15 12.7 0.6 5.4 4 2 0 4 4 4 2 Leucine Rich Repeat PPP4R2 PF09184.11 PVD18347.1 - 0.02 14.5 18.3 0.042 13.5 18.3 1.5 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 PVD18347.1 - 0.13 11.6 20.0 0.23 10.8 20.0 1.3 1 0 0 1 1 1 0 BUD22 Spore_YpjB PF09577.10 PVD18347.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) CENP-Q PF13094.6 PVD18347.1 - 0.14 12.3 4.4 0.36 11.0 4.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_6 PF13516.6 PVD18347.1 - 0.16 12.1 8.0 18 5.7 0.4 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Linker_histone PF00538.19 PVD18348.1 - 4.2e-29 100.7 0.9 4.2e-29 100.7 0.9 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family Rib_hydrolayse PF02267.17 PVD18349.1 - 1e-58 198.6 0.0 1.2e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Ank_2 PF12796.7 PVD18350.1 - 1.8e-31 108.6 9.5 8.2e-11 42.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD18350.1 - 2.9e-25 88.3 8.1 6e-07 29.9 0.9 5.5 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD18350.1 - 1.7e-22 77.1 9.2 0.0007 19.9 0.3 8.0 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 PVD18350.1 - 5.9e-19 67.6 16.1 0.00012 22.4 0.7 7.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 PVD18350.1 - 1.1e-17 63.8 10.2 2.5e-06 27.6 0.6 5.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) AAA_18 PF13238.6 PVD18350.1 - 0.00035 21.1 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD18350.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PVD18350.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 PVD18350.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD18350.1 - 0.012 16.1 0.0 0.034 14.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD18350.1 - 0.015 15.7 0.0 0.071 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 PVD18350.1 - 0.028 14.5 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain SAUGI PF06106.11 PVD18350.1 - 0.031 14.8 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 S. aureus uracil DNA glycosylase inhibitor ABC_tran PF00005.27 PVD18350.1 - 0.044 14.3 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 PVD18350.1 - 0.071 12.6 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 PVD18350.1 - 0.082 13.2 0.8 0.97 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 PVD18350.1 - 0.098 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Cwf_Cwc_15 PF04889.12 PVD18351.1 - 6.4e-76 255.3 20.9 9.1e-76 254.9 20.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF4692 PF15763.5 PVD18351.1 - 0.22 12.0 1.6 0.45 11.0 1.6 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) AAA_23 PF13476.6 PVD18351.1 - 0.3 11.6 7.7 0.43 11.1 7.7 1.2 1 0 0 1 1 1 0 AAA domain DUF755 PF05501.11 PVD18351.1 - 0.69 10.2 11.6 0.18 12.1 6.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Pkinase_Tyr PF07714.17 PVD18353.1 - 4.1e-75 252.4 0.0 5.5e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18353.1 - 1.3e-26 93.5 0.0 2.1e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WIF PF02019.18 PVD18353.1 - 5.1e-19 68.3 0.0 9.7e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 WIF domain Kinase-like PF14531.6 PVD18353.1 - 8.5e-05 22.0 0.6 0.00021 20.7 0.6 1.7 1 1 0 1 1 1 1 Kinase-like Nup88 PF10168.9 PVD18353.1 - 0.0072 14.2 0.5 0.14 10.0 0.0 2.0 2 0 0 2 2 2 2 Nuclear pore component Pkinase_fungal PF17667.1 PVD18353.1 - 0.05 12.4 0.0 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase ABC_tran PF00005.27 PVD18354.1 - 7.4e-49 165.8 0.1 6.1e-28 98.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PVD18354.1 - 6.7e-31 107.9 21.1 1.3e-30 107.0 21.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PVD18354.1 - 7.9e-09 35.3 6.9 0.017 14.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD18354.1 - 0.0016 18.5 0.6 1.3 9.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD18354.1 - 0.002 17.8 2.6 0.22 11.3 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD18354.1 - 0.002 18.5 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 PVD18354.1 - 0.0058 17.2 0.4 3.7 8.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_35 PF14516.6 PVD18354.1 - 0.012 14.5 0.1 0.042 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.14 PVD18354.1 - 0.027 14.4 1.1 0.39 10.6 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 PVD18354.1 - 0.034 14.1 0.5 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 PVD18354.1 - 0.039 13.7 0.2 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PVD18354.1 - 0.049 13.8 1.0 1.3 9.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PVD18354.1 - 0.07 13.6 4.7 0.44 11.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 PVD18354.1 - 0.087 12.5 0.0 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 PVD18354.1 - 0.09 12.5 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 PVD18354.1 - 0.1 12.4 5.3 6.3 6.5 0.3 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PVD18354.1 - 0.1 13.0 0.1 27 5.2 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 PVD18354.1 - 0.11 12.1 0.3 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 PVD18354.1 - 0.11 11.7 4.1 1.2 8.2 0.5 2.9 3 0 0 3 3 3 0 NB-ARC domain PRK PF00485.18 PVD18354.1 - 0.12 12.1 3.3 3.1 7.5 0.3 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 PVD18354.1 - 0.17 11.2 1.4 1.5 8.1 0.5 2.2 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 PVD18354.1 - 0.46 10.7 1.7 13 6.0 0.1 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD18354.1 - 0.52 10.6 5.6 6 7.2 0.0 3.5 4 1 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 PVD18354.1 - 1.1 9.3 5.1 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Dynamin family DUF2207 PF09972.9 PVD18354.1 - 2.7 6.7 10.8 0.33 9.7 0.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Amino_oxidase PF01593.24 PVD18355.1 - 6.4e-41 141.1 0.0 8.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD18355.1 - 2.2e-12 47.0 0.2 4.8e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD18355.1 - 4.9e-06 26.4 0.5 2e-05 24.4 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 PVD18355.1 - 0.00016 20.6 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 PVD18355.1 - 0.00044 19.6 0.2 0.0007 18.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PVD18355.1 - 0.0033 16.6 0.4 0.0064 15.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD18355.1 - 0.0099 15.1 0.2 0.02 14.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PVD18355.1 - 0.042 13.2 0.6 0.061 12.7 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 PVD18355.1 - 0.044 14.4 0.8 0.42 11.2 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PVD18355.1 - 0.064 12.5 0.4 0.17 11.1 0.4 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 7tm_1 PF00001.21 PVD18356.1 - 9.1e-10 38.3 12.0 1.7e-09 37.4 12.0 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD18356.1 - 0.0096 15.6 15.2 0.98 9.0 1.9 3.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx SPRY PF00622.28 PVD18357.1 - 5.2e-11 42.7 0.0 6.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Guanylate_kin PF00625.21 PVD18358.1 - 1.4e-63 213.9 0.1 3e-63 212.8 0.0 1.6 2 0 0 2 2 2 1 Guanylate kinase PDZ PF00595.24 PVD18358.1 - 4.9e-63 209.5 11.3 1.9e-21 76.2 1.2 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 PVD18358.1 - 1.8e-30 104.6 4.4 3.8e-11 42.7 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PVD18358.1 - 4.5e-21 75.0 1.6 5.9e-06 26.5 0.0 4.2 4 0 0 4 4 4 3 PDZ domain SH3_2 PF07653.17 PVD18358.1 - 1.1e-08 34.7 0.0 5.5e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PVD18358.1 - 3e-08 33.2 0.0 1.3e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD18358.1 - 0.011 15.6 0.1 0.047 13.6 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain Mito_carr PF00153.27 PVD18359.1 - 1.1e-54 182.3 2.0 5.9e-23 80.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein AMMECR1 PF01871.17 PVD18360.1 - 1.5e-13 50.7 0.0 1.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 WD40 PF00400.32 PVD18361.1 - 7.3e-12 45.6 9.1 0.0033 18.2 0.2 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18361.1 - 4.9e-06 26.7 0.2 0.0046 17.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PVD18361.1 - 0.0047 17.0 0.1 0.21 11.7 0.0 3.0 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PMM PF03332.13 PVD18361.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase CppA_C PF14507.6 PVD18361.1 - 0.19 12.5 1.0 0.57 10.9 0.2 2.0 2 0 0 2 2 2 0 CppA C-terminal MFS_1 PF07690.16 PVD18362.1 - 4.9e-17 61.9 29.3 1.2e-09 37.5 11.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily CDC27 PF09507.10 PVD18363.1 - 6.5e-42 144.4 42.3 6.5e-42 144.4 42.3 5.8 3 2 2 5 5 5 2 DNA polymerase subunit Cdc27 Med26 PF08711.11 PVD18363.1 - 1.4e-11 44.2 0.0 3.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sulfotransfer_2 PF03567.14 PVD18363.1 - 3.3e-06 27.2 0.1 3.3e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Sulfotransferase family Hepatitis_core PF00906.20 PVD18364.1 - 0.016 14.8 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Hepatitis core antigen Pkinase_Tyr PF07714.17 PVD18365.1 - 0.015 14.6 0.0 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 PVD18366.1 - 3.5e-33 115.1 0.0 4.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18366.1 - 8.9e-27 94.0 0.0 1.1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PVD18366.1 - 5.8e-06 26.0 0.3 0.0021 17.7 0.0 2.1 1 1 1 2 2 2 2 RIO1 family Kdo PF06293.14 PVD18366.1 - 8.2e-05 22.0 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD18366.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD18366.1 - 0.005 16.8 0.7 0.29 11.0 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 PVD18366.1 - 0.02 14.5 0.0 2.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 PVD18366.1 - 0.031 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase cNMP_binding PF00027.29 PVD18367.1 - 2.2e-16 59.7 0.1 7.4e-05 22.7 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain LRR_8 PF13855.6 PVD18368.1 - 1.7e-24 85.3 26.4 8.9e-12 44.6 10.4 4.3 2 1 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.6 PVD18368.1 - 5.1e-13 49.1 0.3 3.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD18368.1 - 3.5e-12 46.3 21.2 1.2e-07 31.9 5.7 5.2 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD18368.1 - 2.5e-08 33.6 8.7 0.004 16.7 0.3 3.1 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PVD18368.1 - 4.3e-06 26.5 20.9 0.9 10.3 0.8 6.4 6 1 0 6 6 6 4 Leucine Rich Repeat CUE PF02845.16 PVD18368.1 - 0.19 11.4 1.0 11 5.8 0.0 2.4 1 1 1 2 2 2 0 CUE domain LRR_8 PF13855.6 PVD18369.1 - 3.9e-30 103.4 42.5 3.4e-11 42.7 0.4 6.4 3 1 4 7 7 7 6 Leucine rich repeat TIR_2 PF13676.6 PVD18369.1 - 4.6e-18 65.9 0.8 1.6e-10 41.6 0.2 2.6 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 PVD18369.1 - 1.7e-16 60.5 0.1 2.2e-08 34.1 0.1 2.5 2 0 0 2 2 2 2 TIR domain LRR_5 PF13306.6 PVD18369.1 - 2.3e-12 47.0 0.4 8.6e-12 45.1 0.1 2.3 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD18369.1 - 2.6e-12 46.8 37.8 0.001 19.4 3.2 8.7 6 1 2 9 9 9 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD18369.1 - 2e-11 43.7 15.5 6.7e-05 22.5 0.2 4.8 3 1 1 5 5 5 3 Leucine-rich repeat TIR-like PF10137.9 PVD18369.1 - 4.6e-05 23.4 0.0 0.61 10.1 0.0 3.4 3 0 0 3 3 3 2 Predicted nucleotide-binding protein containing TIR-like domain LRRNT PF01462.18 PVD18369.1 - 0.12 12.1 6.3 0.062 13.0 2.6 2.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PVD18370.1 - 1.3e-30 104.9 48.0 1.6e-10 40.6 0.3 6.6 4 1 4 8 8 8 6 Leucine rich repeat TIR_2 PF13676.6 PVD18370.1 - 1.3e-18 67.7 0.8 6.3e-12 46.1 0.3 2.8 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 PVD18370.1 - 1e-17 64.5 0.4 1.1e-07 31.9 0.1 2.5 2 0 0 2 2 2 2 TIR domain LRR_4 PF12799.7 PVD18370.1 - 3.1e-14 52.9 44.0 0.00071 19.9 5.8 8.3 6 1 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD18370.1 - 3.2e-13 49.8 0.5 2.7e-12 46.7 0.0 2.8 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD18370.1 - 1e-11 44.6 12.2 2.1e-05 24.1 0.2 4.3 3 1 1 4 4 4 3 Leucine-rich repeat TIR-like PF10137.9 PVD18370.1 - 0.038 13.9 0.0 2.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain LRRNT PF01462.18 PVD18370.1 - 0.12 12.1 5.3 0.047 13.4 1.8 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PVD18370.1 - 1.1 10.1 34.0 21 6.2 0.4 9.6 8 1 0 8 8 8 0 Leucine Rich Repeat DUF3557 PF12078.8 PVD18370.1 - 1.2 9.1 6.2 6.1 6.8 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3557) LRR_8 PF13855.6 PVD18371.1 - 2.3e-28 97.7 34.5 6.5e-10 38.6 7.9 6.7 4 1 3 7 7 7 4 Leucine rich repeat TIR_2 PF13676.6 PVD18371.1 - 1e-19 71.3 0.8 3.9e-11 43.6 0.2 2.8 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 PVD18371.1 - 1.6e-18 67.1 0.4 1.1e-09 38.4 0.2 2.6 2 1 0 2 2 2 2 TIR domain LRR_4 PF12799.7 PVD18371.1 - 1.7e-16 60.1 40.5 0.0001 22.6 3.8 8.5 5 1 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD18371.1 - 1.3e-14 54.3 0.1 1.3e-13 51.0 0.0 2.8 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD18371.1 - 3.2e-12 46.3 13.6 2.2e-05 24.0 0.2 4.2 3 1 1 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 PVD18371.1 - 0.0033 17.0 2.6 0.0033 17.0 2.6 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TIR-like PF10137.9 PVD18371.1 - 0.0098 15.9 0.0 1.9 8.5 0.0 3.2 3 0 0 3 3 3 1 Predicted nucleotide-binding protein containing TIR-like domain DUF3557 PF12078.8 PVD18371.1 - 0.16 11.9 5.5 1.4 8.9 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3557) LRR_1 PF00560.33 PVD18371.1 - 6.4 7.7 31.5 7.9 7.5 0.5 9.1 8 1 0 8 8 8 0 Leucine Rich Repeat TIR_2 PF13676.6 PVD18372.1 - 4.7e-07 30.4 0.0 9.2e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 TIR domain TIR PF01582.20 PVD18372.1 - 2.4e-06 27.5 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD18373.1 - 2.1e-10 40.2 9.7 6.1e-08 32.3 3.3 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PVD18373.1 - 4.2e-10 39.7 14.5 0.00013 22.2 1.0 4.9 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD18373.1 - 5.1e-10 39.4 0.1 9.9e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD18373.1 - 5e-06 26.1 0.2 1.3e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 Leucine-rich repeat TIR_2 PF13676.6 PVD18373.1 - 7e-06 26.6 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD18373.1 - 1.4 9.7 10.6 1.2e+02 3.8 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRRNT PF01462.18 PVD18373.1 - 2.5 7.8 7.0 1.6 8.5 2.6 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PVD18374.1 - 0.083 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF874 PF05917.11 PVD18374.1 - 0.18 10.8 0.4 0.25 10.3 0.4 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) IRS PF02174.17 PVD18375.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) PID_2 PF14719.6 PVD18378.1 - 7.2e-58 195.4 2.4 8.4e-58 195.2 2.4 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 PVD18378.1 - 2.8e-05 24.2 0.2 0.00053 20.0 0.2 2.1 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Homeodomain PF00046.29 PVD18380.1 - 5.1e-15 55.1 0.9 8e-15 54.4 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Renin_r PF07850.14 PVD18381.1 - 6.5e-34 116.5 0.0 1.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Renin receptor-like protein Linker_histone PF00538.19 PVD18382.1 - 2.7e-26 91.7 0.1 2.7e-26 91.7 0.1 2.0 2 1 1 3 3 3 1 linker histone H1 and H5 family Toxin_trans PF07952.12 PVD18382.1 - 0.17 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain YmaF PF12788.7 PVD18385.1 - 7.9 7.1 13.8 1.1 9.9 2.4 3.2 3 0 0 3 3 3 0 YmaF family Linker_histone PF00538.19 PVD18386.1 - 1.9e-29 101.8 0.8 6.9e-29 100.0 0.8 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family Abhydrolase_3 PF07859.13 PVD18387.1 - 2.3e-53 181.2 0.9 1e-40 139.8 0.1 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.28 PVD18387.1 - 6e-06 25.4 1.3 1.6e-05 24.0 1.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 PVD18387.1 - 1.2e-05 24.4 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 PVD18387.1 - 0.00014 21.4 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 PVD18387.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PVD18387.1 - 0.013 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Linker_histone PF00538.19 PVD18388.1 - 1.1e-29 102.6 0.9 4.3e-29 100.7 0.9 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family WD40 PF00400.32 PVD18389.1 - 3.5e-21 75.1 17.5 1.1e-07 32.4 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18389.1 - 7.3e-18 64.7 8.3 1.7e-07 31.4 0.6 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Surp PF01805.20 PVD18389.1 - 9.5e-18 63.9 0.1 9.5e-18 63.9 0.1 2.0 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 PVD18389.1 - 3.8e-14 52.2 0.0 8.7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 PVD18389.1 - 1.8e-08 34.4 3.3 1.8e-08 34.4 3.3 2.3 2 0 0 2 2 2 1 cwf21 domain CTD_bind PF04818.13 PVD18389.1 - 2.1e-05 25.2 0.3 7.5e-05 23.5 0.3 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Ge1_WD40 PF16529.5 PVD18389.1 - 0.0001 21.4 1.0 0.017 14.1 0.3 3.4 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CTK3 PF12243.8 PVD18389.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 PVD18389.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Importin_rep_4 PF18808.1 PVD18390.1 - 4.7e-30 103.7 0.5 4.7e-30 103.7 0.5 4.9 4 1 1 5 5 4 1 Importin repeat HEAT_EZ PF13513.6 PVD18390.1 - 4e-21 75.1 6.7 1.1e-12 48.2 0.0 9.3 9 1 1 10 10 9 2 HEAT-like repeat HEAT_2 PF13646.6 PVD18390.1 - 9.6e-19 67.6 0.0 1e-09 38.7 0.0 7.0 5 2 1 6 6 5 2 HEAT repeats HEAT PF02985.22 PVD18390.1 - 5.1e-18 63.6 10.2 1.1e-05 25.2 0.0 9.8 13 0 0 13 13 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 PVD18390.1 - 1.3e-12 48.2 12.0 1.4e-05 25.6 0.0 8.5 7 2 3 10 10 8 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 PVD18390.1 - 2e-09 37.5 2.2 8.3e-09 35.5 0.1 3.2 4 0 0 4 4 3 1 Importin repeat 6 RIX1 PF08167.12 PVD18390.1 - 1.3e-08 34.8 4.5 0.51 10.0 0.7 6.5 5 2 2 7 7 7 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 PVD18390.1 - 3.9e-07 29.0 10.8 0.00012 20.8 1.2 4.2 3 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 PVD18390.1 - 7.2e-07 28.6 5.2 0.0085 15.2 0.4 5.3 4 1 2 6 6 6 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 PVD18390.1 - 1.4e-05 25.2 5.1 0.0015 18.6 0.1 4.7 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 PVD18390.1 - 1.9e-05 24.4 3.4 2.7 7.5 0.0 5.3 5 1 1 6 6 6 1 Tti2 family Xpo1 PF08389.12 PVD18390.1 - 5.1e-05 23.4 0.9 0.2 11.7 0.1 5.0 4 1 0 5 5 5 1 Exportin 1-like protein Arm PF00514.23 PVD18390.1 - 5.5e-05 23.1 0.4 0.13 12.4 0.1 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 PVD18390.1 - 0.00038 20.9 0.1 1 10.2 0.0 4.5 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat Importin_rep_5 PF18816.1 PVD18390.1 - 0.0035 17.6 0.0 0.028 14.7 0.0 2.7 1 0 0 1 1 1 1 Importin repeat Sec7_N PF12783.7 PVD18390.1 - 0.0059 16.5 2.4 5.4 6.9 0.6 5.5 3 2 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal BP28CT PF08146.12 PVD18390.1 - 0.019 14.8 0.4 8.6 6.2 0.1 3.7 3 0 0 3 3 3 0 BP28CT (NUC211) domain TAF6_C PF07571.13 PVD18390.1 - 0.04 14.2 0.0 0.85 10.0 0.0 3.4 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain CTD_bind PF04818.13 PVD18390.1 - 0.82 10.5 2.4 4.5e+02 1.8 0.0 5.8 7 0 0 7 7 4 0 RNA polymerase II-binding domain. Astacin PF01400.24 PVD18391.1 - 1.2e-44 152.3 2.3 7.9e-35 120.2 0.2 2.5 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) ShK PF01549.24 PVD18391.1 - 8.6e-21 74.2 84.8 8.6e-07 29.4 11.4 6.0 6 0 0 6 6 6 4 ShK domain-like Peptidase_M10 PF00413.24 PVD18391.1 - 0.033 14.1 3.8 0.62 9.9 1.1 2.5 1 1 1 2 2 2 0 Matrixin zf-CCCH PF00642.24 PVD18391.1 - 0.086 12.8 7.5 10 6.1 0.5 4.8 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Reprolysin_5 PF13688.6 PVD18391.1 - 0.24 11.5 7.5 0.66 10.1 0.0 3.0 3 1 0 3 3 3 0 Metallo-peptidase family M12 AMP-binding PF00501.28 PVD18392.1 - 3e-97 325.9 0.0 3.5e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18392.1 - 8.6e-05 23.4 0.0 0.00029 21.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain PLDc_3 PF13918.6 PVD18392.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain RhoGEF PF00621.20 PVD18393.1 - 7.1e-32 111.1 0.1 1.2e-31 110.4 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 PVD18393.1 - 4e-16 58.6 0.1 7.1e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD18393.1 - 3.9e-15 55.2 0.1 7.6e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD18393.1 - 2.2e-14 52.9 0.6 4.8e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF67_u2 PF16614.5 PVD18393.1 - 2.6e-11 43.6 7.1 1.7e-05 24.8 0.1 2.7 1 1 1 2 2 2 2 Unstructured region two on RhoGEF 6 and 7 PH PF00169.29 PVD18393.1 - 0.00012 22.5 0.0 0.00036 21.0 0.0 1.9 1 0 0 1 1 1 1 PH domain betaPIX_CC PF16523.5 PVD18394.1 - 2.2e-19 69.1 1.6 2.9e-19 68.7 1.6 1.1 1 0 0 1 1 1 1 betaPIX coiled coil CCDC144C PF14915.6 PVD18394.1 - 0.00012 21.4 1.8 0.00013 21.2 1.8 1.0 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.19 PVD18394.1 - 0.00045 18.2 1.6 0.0005 18.0 1.6 1.0 1 0 0 1 1 1 1 Myosin tail PI3K_P85_iSH2 PF16454.5 PVD18394.1 - 0.0098 15.5 3.1 0.012 15.2 3.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cauli_AT PF03233.13 PVD18394.1 - 0.033 14.1 0.6 0.04 13.8 0.6 1.1 1 0 0 1 1 1 0 Aphid transmission protein DUF724 PF05266.14 PVD18394.1 - 0.037 13.9 0.6 0.042 13.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) JAKMIP_CC3 PF16034.5 PVD18394.1 - 0.04 13.9 4.0 0.05 13.6 4.0 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain EMP24_GP25L PF01105.24 PVD18394.1 - 0.041 13.8 0.6 0.051 13.5 0.6 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SH3_1 PF00018.28 PVD18395.1 - 2.4e-45 151.9 3.0 8.1e-14 51.0 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 PVD18395.1 - 5.9e-41 138.1 1.9 6.8e-15 54.7 0.0 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 PVD18395.1 - 3.3e-31 106.7 0.1 2.2e-11 43.3 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 PVD18395.1 - 3e-22 78.5 0.3 7.6e-22 77.2 0.3 1.8 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 PVD18395.1 - 5.5e-08 33.0 6.4 0.00045 20.4 0.2 3.8 4 0 0 4 4 4 2 Bacterial SH3 domain SH3_10 PF17902.1 PVD18395.1 - 1.8e-07 31.1 0.9 0.0021 18.1 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SH2_2 PF14633.6 PVD18395.1 - 7.1e-06 25.6 0.1 1.7e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 SH2 domain hSH3 PF14603.6 PVD18395.1 - 0.0003 21.1 0.0 0.21 12.1 0.0 3.4 3 0 0 3 3 3 1 Helically-extended SH3 domain Myc_target_1 PF15179.6 PVD18396.1 - 0.11 12.3 1.7 0.13 12.1 0.3 1.8 2 0 0 2 2 2 0 Myc target protein 1 Porph_ging PF09697.10 PVD18396.1 - 1.9 9.1 5.0 3.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (Porph_ging) Choline_kinase PF01633.20 PVD18397.1 - 1.2e-50 172.1 0.0 1.7e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PVD18397.1 - 1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PVD18397.1 - 0.00058 19.3 0.5 0.00094 18.6 0.5 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fz PF01392.22 PVD18398.1 - 1.7 9.3 5.3 0.49 11.0 2.0 1.7 1 1 1 2 2 2 0 Fz domain DEAD PF00270.29 PVD18401.1 - 9.5e-46 155.8 0.1 1.6e-45 155.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD18401.1 - 3.6e-25 88.5 0.6 3.6e-24 85.2 0.3 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD18401.1 - 5.1e-07 29.9 0.0 8.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD18401.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD18401.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 PVD18401.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase DAGK_acc PF00609.19 PVD18402.1 - 5.4e-51 173.1 0.0 1.1e-50 172.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PVD18402.1 - 1.7e-23 82.6 0.0 5.9e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain SAM_1 PF00536.30 PVD18402.1 - 2.1e-19 69.7 1.2 9.6e-19 67.6 0.1 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 PVD18402.1 - 4.3e-19 68.1 21.9 6.1e-10 38.8 3.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 PVD18402.1 - 6.1e-18 64.7 1.3 2.4e-17 62.8 0.1 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PH PF00169.29 PVD18402.1 - 3e-06 27.7 1.0 4.5e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 PH domain C1_2 PF03107.16 PVD18402.1 - 0.0028 18.0 16.5 0.043 14.1 6.1 2.6 2 0 0 2 2 2 2 C1 domain SAM_4 PF18017.1 PVD18402.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF5344 PF17279.2 PVD18402.1 - 4.8 7.8 7.7 12 6.6 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF883 PF05957.13 PVD18402.1 - 5.6 7.6 7.8 4.2 8.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Na_K-ATPase PF00287.18 PVD18403.1 - 1.5e-65 221.2 0.0 1.7e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Na_K-ATPase PF00287.18 PVD18404.1 - 3.5e-60 203.6 0.0 3.9e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Glyco_trans_2_3 PF13632.6 PVD18404.1 - 2.4e-05 24.3 0.7 0.0031 17.4 0.4 2.2 2 0 0 2 2 2 2 Glycosyl transferase family group 2 GFO_IDH_MocA PF01408.22 PVD18405.1 - 2.9e-11 44.3 0.4 6.5e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD18405.1 - 4.7e-05 23.4 0.0 7.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Na_K-ATPase PF00287.18 PVD18406.1 - 3.5e-57 193.7 1.2 4e-57 193.6 1.2 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Glyco_trans_2_3 PF13632.6 PVD18406.1 - 2.1e-05 24.6 1.1 0.0061 16.5 1.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family group 2 PQ-loop PF04193.14 PVD18407.1 - 1.4e-18 66.4 8.1 2.4e-10 40.0 1.9 3.4 4 0 0 4 4 4 2 PQ loop repeat MerC PF03203.14 PVD18407.1 - 1.2 9.6 10.0 0.35 11.3 1.4 2.6 1 1 2 3 3 3 0 MerC mercury resistance protein Sulfatase PF00884.23 PVD18408.1 - 3.9e-11 42.9 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD18408.1 - 5e-06 26.7 0.1 1e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 PVD18408.1 - 0.0011 19.7 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD18408.1 - 0.035 14.0 0.1 0.17 11.8 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function TFIIE_beta PF02186.15 PVD18409.1 - 6e-18 64.9 0.0 1.7e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 PVD18409.1 - 6.9e-10 38.5 0.0 1.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 Pol_alpha_B_N PF08418.10 PVD18409.1 - 0.0012 18.9 1.6 0.0025 17.8 1.6 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Serpin PF00079.20 PVD18410.1 - 9.7e-59 199.5 0.0 1.8e-58 198.7 0.0 1.4 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18411.1 - 1.5e-81 274.6 0.0 2e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18412.1 - 3.2e-91 306.4 0.0 4.7e-91 305.9 0.0 1.2 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1275 PF06912.11 PVD18412.1 - 0.52 10.2 3.2 0.29 11.0 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Serpin PF00079.20 PVD18413.1 - 3.9e-80 269.9 0.0 4.5e-74 250.0 0.0 2.1 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) DUF5420 PF17457.2 PVD18413.1 - 0.041 13.8 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5420) Serpin PF00079.20 PVD18414.1 - 4.8e-154 513.2 0.0 2.3e-82 277.3 0.1 2.1 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) DUF237 PF03072.14 PVD18414.1 - 0.00054 20.0 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF237) Serpin PF00079.20 PVD18415.1 - 3.9e-67 227.2 0.0 4.5e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18416.1 - 4e-176 585.8 0.0 9.5e-91 304.9 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) Arch_flagellin PF01917.16 PVD18416.1 - 0.085 13.0 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Archaebacterial flagellin Serpin PF00079.20 PVD18417.1 - 2.2e-13 50.3 0.1 2.3e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18418.1 - 1.6e-40 139.6 0.0 1.7e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18420.1 - 2.9e-100 336.2 0.0 3.3e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18421.1 - 1.7e-75 254.7 0.0 7e-75 252.6 0.0 1.7 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18422.1 - 9.5e-171 568.1 0.0 3.4e-94 316.2 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) Arcadin_1 PF18653.1 PVD18422.1 - 0.09 12.8 0.0 7 6.8 0.0 2.6 2 0 0 2 2 2 0 Arcadin 1 CUB_2 PF02408.20 PVD18423.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 CUB-like domain PIP49_C PF12260.8 PVD18424.1 - 5e-06 26.3 0.1 7.6e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 PVD18424.1 - 0.015 14.6 0.6 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase DUF5628 PF18621.1 PVD18424.1 - 0.18 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5628) RYDR_ITPR PF01365.21 PVD18425.1 - 9e-30 103.6 15.0 4.9e-23 81.6 2.0 3.8 3 0 0 3 3 3 2 RIH domain Ins145_P3_rec PF08709.11 PVD18425.1 - 1.7e-26 92.8 0.4 8.5e-26 90.5 0.5 2.1 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 PVD18425.1 - 3.2e-18 65.4 11.8 1.5e-17 63.2 1.1 4.7 4 0 0 4 4 4 1 RyR and IP3R Homology associated MIR PF02815.19 PVD18425.1 - 4.1e-17 62.6 4.4 2.5e-12 47.0 0.1 4.1 2 2 1 3 3 3 3 MIR domain Ion_trans PF00520.31 PVD18425.1 - 1.6e-09 37.4 13.6 1.6e-09 37.4 13.6 2.0 2 0 0 2 2 2 1 Ion transport protein Fascin PF06268.13 PVD18425.1 - 0.008 16.4 0.1 0.059 13.6 0.0 2.5 2 0 0 2 2 2 1 Fascin domain Herpes_U47 PF05467.11 PVD18425.1 - 0.044 11.9 0.2 0.072 11.2 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 DUF1604 PF07713.13 PVD18426.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) DUF4707 PF15806.5 PVD18427.1 - 7.9e-33 114.0 0.2 1.3e-32 113.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4707) RBP_receptor PF14752.6 PVD18428.1 - 3e-112 376.2 19.1 3.8e-112 375.9 19.1 1.1 1 0 0 1 1 1 1 Retinol binding protein receptor Sid-5 PF17204.3 PVD18428.1 - 0.0027 17.8 0.2 0.0027 17.8 0.2 3.2 3 1 1 4 4 4 1 Sid-5 family zf-C3HC4 PF00097.25 PVD18429.1 - 1.2e-08 34.6 9.8 2.9e-08 33.4 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD18429.1 - 2.5e-08 33.8 7.4 2.5e-08 33.8 7.4 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD18429.1 - 1.8e-07 31.2 11.8 4.4e-07 30.0 11.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD18429.1 - 2e-07 30.7 8.7 2e-07 30.7 8.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD18429.1 - 6.9e-07 29.0 11.3 1.6e-06 27.8 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD18429.1 - 9.2e-07 29.1 11.0 9.2e-07 29.1 11.0 1.9 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 PVD18429.1 - 2e-06 27.6 9.6 2e-06 27.6 9.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD18429.1 - 4.7e-05 23.3 7.8 0.00012 21.9 7.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 PVD18429.1 - 0.0089 16.1 6.5 0.0089 16.1 6.5 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PVD18429.1 - 0.013 15.6 3.1 0.032 14.3 3.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PI-TkoII_IV PF18714.1 PVD18429.1 - 0.076 12.5 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV DUF4359 PF14271.6 PVD18429.1 - 0.085 13.6 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) zf-rbx1 PF12678.7 PVD18429.1 - 0.67 10.3 9.8 0.52 10.6 7.5 2.1 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PVD18429.1 - 4.5 7.1 17.6 0.071 12.9 7.7 2.8 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF229 PF02995.17 PVD18430.1 - 1.8e-92 310.5 0.0 1.5e-91 307.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18430.1 - 0.00078 18.9 0.2 0.0039 16.6 0.0 2.0 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 PVD18430.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD18430.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 PVD18431.1 - 6.1e-18 64.7 0.4 2.5e-17 62.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF229 PF02995.17 PVD18432.1 - 2.8e-78 263.7 0.0 3.9e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18432.1 - 0.00091 18.7 3.3 0.0085 15.5 1.0 2.2 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 PVD18432.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 PVD18433.1 - 2.1e-95 320.2 0.1 4.9e-95 319.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18433.1 - 0.00089 18.7 2.1 0.0059 16.0 0.0 2.2 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 PVD18433.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase HATPase_c_3 PF13589.6 PVD18434.1 - 0.014 15.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3684 PF12449.8 PVD18436.1 - 0.0074 14.1 1.2 0.011 13.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) DUF5638 PF18688.1 PVD18436.1 - 0.12 12.7 1.5 1.5 9.2 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Suppressor_P21 PF11479.8 PVD18436.1 - 0.25 11.6 1.6 1.4 9.2 0.3 2.5 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain DUF758 PF05527.11 PVD18436.1 - 0.75 9.8 6.0 1.2 9.1 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF758) HEPN PF05168.14 PVD18439.1 - 1.8e-09 37.7 0.0 3.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 HEPN domain DDE_Tnp_1_7 PF13843.6 PVD18440.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 PVD18440.1 - 0.18 12.6 11.4 0.94 10.3 10.8 2.4 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon RGM_N PF06535.12 PVD18441.1 - 0.13 12.5 2.5 0.15 12.2 1.4 1.5 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus WAP PF00095.21 PVD18443.1 - 3.8e-06 27.2 12.0 5.6e-06 26.6 12.0 1.3 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAN_4 PF14295.6 PVD18444.1 - 0.014 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 PAN domain CobT PF06213.12 PVD18445.1 - 0.084 12.2 10.0 0.12 11.7 10.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 PVD18445.1 - 0.1 12.4 11.9 0.12 12.2 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 PVD18445.1 - 0.24 11.5 2.0 0.29 11.3 2.0 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 PVD18445.1 - 0.43 10.9 18.8 0.75 10.1 18.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 PVD18445.1 - 0.56 9.9 10.4 0.91 9.2 10.4 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 PVD18445.1 - 0.64 8.7 5.6 0.72 8.5 5.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 PVD18445.1 - 0.68 7.9 9.3 0.82 7.7 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 PVD18445.1 - 0.86 9.6 3.3 1.3 9.0 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 PVD18445.1 - 1.1 8.4 4.2 1.4 8.1 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 PVD18445.1 - 1.5 7.6 11.3 2.3 6.9 11.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF_C PF14721.6 PVD18445.1 - 2.1 8.7 6.7 11 6.4 7.2 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GEN1_C PF18380.1 PVD18445.1 - 4 8.4 10.3 10 7.1 10.3 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Eapp_C PF10238.9 PVD18445.1 - 7.1 6.7 10.4 18 5.4 10.4 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAM176 PF14851.6 PVD18445.1 - 8 6.1 8.2 15 5.3 8.2 1.4 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.19 PVD18445.1 - 9.8 3.9 9.7 13 3.6 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-set PF07686.17 PVD18447.1 - 0.00073 19.7 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 PVD18447.1 - 0.001 19.2 0.7 0.0028 17.8 0.7 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD18447.1 - 0.0048 17.5 0.2 0.016 15.8 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD18447.1 - 0.0058 16.7 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD18447.1 - 0.031 14.6 0.9 0.031 14.6 0.9 2.1 2 1 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 PVD18447.1 - 0.18 11.4 1.7 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 PVD18448.1 - 1.3e-05 25.7 3.0 1.5 9.5 0.1 4.5 3 2 1 4 4 4 3 Immunoglobulin domain CBM_14 PF01607.24 PVD18448.1 - 0.0011 19.1 5.6 0.0011 19.1 5.6 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Big_7 PF17957.1 PVD18448.1 - 0.74 10.6 8.5 1.4 9.7 1.0 2.9 3 0 0 3 3 3 0 Bacterial Ig domain Ig_3 PF13927.6 PVD18449.1 - 1e-11 45.3 2.1 3.7e-07 30.7 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD18449.1 - 3.7e-09 36.6 4.8 2.2e-06 27.7 0.3 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD18449.1 - 1.2e-06 28.4 0.6 0.00041 20.3 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin I-set domain CBM_14 PF01607.24 PVD18449.1 - 0.0028 17.8 4.9 0.0071 16.5 4.9 1.8 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain V-set PF07686.17 PVD18449.1 - 0.0048 17.0 0.7 0.097 12.8 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Big_7 PF17957.1 PVD18449.1 - 0.067 14.0 2.4 7.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial Ig domain Ig_2 PF13895.6 PVD18449.1 - 0.2 12.0 1.7 4.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 PVD18450.1 - 0.00048 20.2 0.2 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD18450.1 - 0.00053 20.5 2.5 0.034 14.7 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD18450.1 - 0.0039 17.3 2.1 0.0077 16.4 0.2 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 PVD18450.1 - 0.0052 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD18450.1 - 0.034 14.5 0.3 0.034 14.5 0.3 2.5 2 1 0 2 2 2 0 Immunoglobulin domain RNA_pol_Rpb1_1 PF04997.12 PVD18451.1 - 7.8e-107 357.2 0.3 1.8e-106 356.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 PVD18451.1 - 2.1e-99 332.3 0.1 3.2e-99 331.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PVD18451.1 - 1.4e-75 253.1 0.1 2.8e-75 252.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PVD18451.1 - 2e-68 230.0 1.0 4.7e-68 228.8 1.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 PVD18451.1 - 1.2e-55 187.2 4.4 2.8e-55 186.0 4.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 PVD18451.1 - 1.5e-48 164.7 0.0 3.4e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PVD18451.1 - 6.3e-15 55.0 0.0 2.6e-14 53.1 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 PVD18451.1 - 2.9e-06 27.3 407.0 0.037 14.4 7.3 20.9 11 2 8 23 23 23 17 RNA polymerase Rpb1 C-terminal repeat BTB PF00651.31 PVD18452.1 - 1.6e-24 86.3 0.2 2.8e-22 79.0 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain Kelch_1 PF01344.25 PVD18452.1 - 6.4e-18 64.1 0.6 4.1e-05 23.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 PVD18452.1 - 4.3e-17 62.1 0.5 1.1e-16 60.8 0.5 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 PVD18452.1 - 3.9e-16 58.7 1.9 5.1e-06 26.6 0.0 5.0 2 1 3 5 5 5 4 Kelch motif Kelch_4 PF13418.6 PVD18452.1 - 1.8e-12 47.1 0.2 4.9e-07 29.7 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD18452.1 - 0.00021 21.5 3.4 0.75 10.2 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Skp1_POZ PF03931.15 PVD18452.1 - 0.00075 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Kelch_5 PF13854.6 PVD18452.1 - 0.0021 18.0 0.1 0.44 10.6 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Na_H_Exchanger PF00999.21 PVD18453.1 - 7.4e-63 212.6 42.6 8.7e-63 212.4 42.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Agarase_CBM PF17992.1 PVD18453.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Agarase CBM like domain DUF755 PF05501.11 PVD18453.1 - 0.15 12.4 3.0 0.28 11.4 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Glyco_transf_24 PF18404.1 PVD18454.1 - 1.4e-147 490.3 3.0 2.3e-147 489.6 3.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 PVD18454.1 - 8.4e-57 192.5 0.2 1.8e-47 162.0 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain UDP-g_GGTase PF06427.11 PVD18454.1 - 2.5e-37 127.3 0.0 7e-37 125.9 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 PVD18454.1 - 5.6e-36 123.5 0.8 1.6e-35 121.9 0.8 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 PVD18454.1 - 1.1e-32 114.0 0.3 3.8e-30 105.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 PVD18454.1 - 6.8e-19 68.5 2.3 7e-11 42.3 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 PVD18454.1 - 4.7e-06 26.3 0.3 9.2e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 UNC-93 PF05978.16 PVD18455.1 - 3.2e-11 43.2 16.5 6.5e-11 42.2 4.0 3.7 2 1 1 3 3 3 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 PVD18455.1 - 1.8e-06 27.2 36.1 0.0012 17.9 16.2 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD18455.1 - 0.00058 18.5 6.6 0.00058 18.5 6.6 3.5 3 1 0 4 4 4 1 MFS/sugar transport protein FidL_like PF15941.5 PVD18455.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 FidL-like putative membrane protein Ferlin_C PF16165.5 PVD18455.1 - 2.6 8.0 7.6 0.83 9.6 0.8 2.6 2 0 0 2 2 2 0 Ferlin C-terminus Peptidase_M3 PF01432.20 PVD18456.1 - 6.8e-109 365.1 0.0 4.5e-104 349.2 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M3 eIF2A PF08662.11 PVD18456.1 - 6e-67 225.3 0.0 1.1e-65 221.2 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 PVD18456.1 - 0.0098 15.0 0.0 2.4 7.1 0.0 2.5 2 1 0 2 2 2 2 Coatomer WD associated region Serpin PF00079.20 PVD18457.1 - 2.2e-225 747.9 0.1 1.8e-113 379.7 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) MRP-S25 PF13741.6 PVD18457.1 - 0.062 12.8 1.4 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 HTH_20 PF12840.7 PVD18457.1 - 4.6 7.4 7.0 40 4.4 0.1 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain Serpin PF00079.20 PVD18458.1 - 2e-101 340.0 0.0 2.5e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18459.1 - 7.3e-119 397.4 0.1 8.2e-119 397.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 PVD18460.1 - 1.1e-36 127.0 0.1 1.3e-36 126.7 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MRP-S25 PF13741.6 PVD18460.1 - 0.043 13.4 0.4 0.057 13.0 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Serpin PF00079.20 PVD18461.1 - 5e-68 230.1 0.0 5.6e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RPN2_C PF18004.1 PVD18462.1 - 1.7e-46 158.1 8.5 3.2e-46 157.2 8.5 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 PVD18462.1 - 5.7e-29 99.1 19.0 1.2e-08 34.9 0.1 7.1 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PVD18462.1 - 1.2e-17 64.1 0.9 3e-13 50.0 0.0 4.0 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 PVD18462.1 - 0.002 18.2 0.7 22 5.7 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 PVD18462.1 - 0.0028 18.1 0.7 0.024 15.1 0.0 3.1 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 PVD18462.1 - 0.0089 16.1 0.0 0.55 10.3 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 BSP_II PF05432.11 PVD18462.1 - 0.045 13.5 5.8 0.076 12.7 5.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SR-25 PF10500.9 PVD18462.1 - 0.05 13.2 9.5 0.082 12.5 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Clathrin_H_link PF13838.6 PVD18462.1 - 0.083 12.8 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 Clathrin-H-link DUF4887 PF16228.5 PVD18462.1 - 3.4 7.8 0.0 3.4 7.8 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4887) Med12-LCEWAV PF12145.8 PVD18463.1 - 4.3e-148 494.1 2.4 4.3e-148 494.1 2.4 2.0 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 PVD18463.1 - 1e-16 61.0 0.3 3.7e-16 59.2 0.1 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 BORCS7 PF16088.5 PVD18463.1 - 0.35 11.1 1.9 2.2 8.6 0.1 3.2 4 0 0 4 4 4 0 BLOC-1-related complex sub-unit 7 Xpo1 PF08389.12 PVD18463.1 - 4 7.5 11.8 1.8 8.6 0.1 4.7 4 1 2 6 6 6 0 Exportin 1-like protein DNA_pol_B PF00136.21 PVD18466.1 - 6.5e-129 430.6 2.3 9.7e-129 430.0 2.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 PVD18466.1 - 2.2e-44 151.4 4.1 5e-44 150.3 4.1 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 PVD18466.1 - 2.2e-42 145.4 1.1 6.1e-42 143.9 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 PVD18466.1 - 8.6e-20 70.6 9.4 2.6e-19 69.0 9.4 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 PVD18466.1 - 0.00016 20.7 0.0 0.00036 19.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 PVD18466.1 - 0.0015 17.2 0.1 0.0027 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) TPK_catalytic PF04263.16 PVD18466.1 - 0.088 12.9 0.8 77 3.4 0.0 3.8 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, catalytic domain Sulfotransfer_1 PF00685.27 PVD18468.1 - 7.7e-68 228.9 0.1 9e-68 228.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD18468.1 - 2.7e-08 34.5 0.0 0.0016 18.9 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family zf-H2C2_5 PF13909.6 PVD18468.1 - 0.0012 18.6 0.4 0.0032 17.2 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain Ank_2 PF12796.7 PVD18469.1 - 1.2e-50 170.1 4.5 1.4e-16 60.9 0.1 4.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD18469.1 - 5.7e-34 116.1 2.0 2.6e-10 40.6 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD18469.1 - 8.3e-31 102.6 4.3 7.3e-05 22.9 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 PVD18469.1 - 3.3e-28 96.9 12.5 7.7e-06 26.1 0.2 8.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD18469.1 - 3.8e-24 84.4 4.8 4.7e-08 33.2 0.0 6.7 3 2 4 7 7 7 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD18469.1 - 4e-05 23.9 1.7 9.8e-05 22.6 1.7 1.7 1 0 0 1 1 1 1 SOCS box HrpE PF06188.12 PVD18469.1 - 0.061 13.2 0.3 0.093 12.6 0.3 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E SDF PF00375.18 PVD18470.1 - 9.9e-65 219.0 26.6 3.7e-41 141.4 13.5 3.0 2 1 1 3 3 3 3 Sodium:dicarboxylate symporter family NUFIP1 PF10453.9 PVD18471.1 - 1.4e-14 53.7 9.4 1.4e-14 53.7 9.4 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Spore_YhcN_YlaJ PF09580.10 PVD18471.1 - 1.6 8.8 8.4 0.3 11.2 0.6 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RabGAP-TBC PF00566.18 PVD18472.1 - 1.7e-28 99.7 0.0 2.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phostensin_N PF13916.6 PVD18475.1 - 0.39 11.1 13.8 5.5 7.4 0.0 4.6 4 1 1 5 5 5 0 PP1-regulatory protein, Phostensin N-terminal Myosin_head PF00063.21 PVD18477.1 - 1.3e-91 307.9 3.3 3.2e-57 194.2 0.0 4.1 1 1 3 4 4 4 4 Myosin head (motor domain) Ank_4 PF13637.6 PVD18477.1 - 3.4e-27 94.4 1.8 1e-11 45.1 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD18477.1 - 4.6e-26 91.2 1.1 1.4e-11 44.8 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD18477.1 - 1.3e-22 79.2 8.0 3.4e-05 24.1 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PVD18477.1 - 8e-21 73.8 6.5 4.2e-09 36.5 0.4 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD18477.1 - 5.1e-20 69.4 2.2 0.0025 18.2 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat ARGLU PF15346.6 PVD18478.1 - 1.8e-51 174.0 62.0 1.8e-51 174.0 62.0 2.7 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 LAP1C PF05609.12 PVD18479.1 - 0.29 10.2 2.8 0.44 9.6 2.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 PVD18480.1 - 0.4 10.0 3.9 0.47 9.8 3.9 1.1 1 0 0 1 1 1 0 BUD22 SCHIP-1 PF10148.9 PVD18481.1 - 3.1e-61 207.0 11.0 1.4e-60 204.8 11.0 1.8 1 1 0 1 1 1 1 Schwannomin-interacting protein 1 AMP-binding_C_2 PF14535.6 PVD18481.1 - 0.13 12.5 2.8 1.7 9.0 0.3 2.4 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 PVD18482.1 - 6e-38 130.7 44.7 1.1e-19 70.6 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD18482.1 - 0.12 11.2 39.2 0.0057 15.6 11.5 2.8 1 1 0 2 2 2 0 Sugar (and other) transporter EMP24_GP25L PF01105.24 PVD18483.1 - 0.00022 21.2 6.2 0.00022 21.2 6.2 6.8 4 4 1 5 5 5 1 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 PVD18483.1 - 0.0015 18.6 2.5 0.0015 18.6 2.5 9.5 5 2 4 10 10 10 1 TolA binding protein trimerisation Spc7 PF08317.11 PVD18483.1 - 0.002 17.1 23.8 0.002 17.1 23.8 6.5 1 1 7 8 8 8 1 Spc7 kinetochore protein T3SSipB PF16535.5 PVD18483.1 - 0.0047 17.4 8.3 0.0047 17.4 8.3 6.6 2 2 2 6 6 6 1 Type III cell invasion protein SipB Cep57_CLD_2 PF14197.6 PVD18483.1 - 0.012 15.6 1.9 0.012 15.6 1.9 12.6 6 3 9 15 15 15 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 PVD18483.1 - 0.96 10.0 160.5 0.047 14.2 16.4 8.3 4 2 5 9 9 9 0 Apg6 coiled-coil region APG6_N PF17675.1 PVD18484.1 - 0.007 16.9 22.1 0.007 16.9 22.1 8.5 2 2 6 8 8 8 6 Apg6 coiled-coil region GRIP PF01465.20 PVD18485.1 - 2.6e-14 52.8 1.0 2.6e-14 52.8 1.0 2.5 2 0 0 2 2 2 1 GRIP domain Rab_bind PF16704.5 PVD18485.1 - 4.4e-10 39.4 4.7 4.4e-10 39.4 4.7 3.6 2 0 0 2 2 2 1 Rab binding domain Taxilin PF09728.9 PVD18485.1 - 0.0022 17.2 39.1 0.0022 17.2 39.1 5.0 3 1 2 5 5 5 3 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 PVD18485.1 - 0.005 16.9 112.7 0.43 10.6 22.3 7.9 3 1 4 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 PVD18485.1 - 1.9 7.8 57.1 0.034 13.5 2.2 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Img2 PF05046.14 PVD18485.1 - 8.4 6.8 6.6 2.6 8.4 0.5 3.5 3 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) T2SSG PF08334.11 PVD18485.1 - 8.7 6.5 8.1 1.5 8.9 0.2 3.7 3 1 0 4 4 4 0 Type II secretion system (T2SS), protein G LRR_4 PF12799.7 PVD18486.1 - 4.8e-23 80.9 20.5 2.3e-06 27.9 0.1 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD18486.1 - 9.6e-22 76.5 27.0 4.8e-08 32.7 0.9 5.8 2 1 4 6 6 6 6 Leucine rich repeat Roc PF08477.13 PVD18486.1 - 1.4e-13 51.1 0.0 3.6e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 PVD18486.1 - 2.8e-11 43.6 0.0 1.5e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 PVD18486.1 - 2.1e-10 40.4 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_9 PF14580.6 PVD18486.1 - 0.001 18.6 8.3 0.26 10.8 1.2 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 PVD18486.1 - 0.0035 17.3 22.2 0.036 14.1 0.4 7.3 7 1 1 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.33 PVD18486.1 - 0.24 12.1 22.8 6.4 7.7 0.0 8.7 7 3 0 7 7 7 0 Leucine Rich Repeat 7tm_2 PF00002.24 PVD18487.1 - 5.4e-16 58.6 14.4 7.6e-16 58.1 14.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CTP_transf_like PF01467.26 PVD18488.1 - 5.9e-27 94.6 0.0 9.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Pkinase PF00069.25 PVD18489.1 - 6.2e-71 238.8 0.0 7.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18489.1 - 1.2e-52 178.8 0.0 1.6e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD18489.1 - 1.3e-05 24.2 0.0 1.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 PVD18489.1 - 2.2e-05 24.2 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 PVD18489.1 - 0.005 15.8 0.1 0.042 12.8 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD18489.1 - 0.0083 15.5 0.0 0.094 12.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD18489.1 - 0.12 12.2 0.0 9.6 6.0 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family PP2C PF00481.21 PVD18490.1 - 1.3e-58 198.6 0.0 1.5e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PVD18490.1 - 2.4e-05 24.0 0.0 7.6e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Lyase_aromatic PF00221.19 PVD18490.1 - 0.063 11.9 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase Ras PF00071.22 PVD18491.1 - 6.8e-57 191.6 0.0 7.7e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD18491.1 - 9.6e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD18491.1 - 2.2e-08 33.8 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD18491.1 - 3.1e-05 23.9 0.0 0.11 12.4 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PVD18491.1 - 0.0011 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 PVD18491.1 - 0.0099 14.9 0.4 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 PVD18491.1 - 0.014 15.0 0.1 0.047 13.2 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD18491.1 - 0.03 13.9 0.3 0.21 11.1 0.1 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain zf-H2C2_5 PF13909.6 PVD18492.1 - 1.3e-12 47.2 29.9 9.5e-08 31.7 1.5 4.7 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD18492.1 - 1.7e-10 40.8 39.9 0.00011 22.5 4.7 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD18492.1 - 8.2e-06 26.0 0.5 8.2e-06 26.0 0.5 6.0 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD18492.1 - 0.00018 22.1 37.4 0.0078 17.0 0.7 6.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD18492.1 - 0.016 15.4 3.8 0.016 15.4 3.8 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 PVD18492.1 - 0.062 13.8 4.5 0.58 10.6 1.4 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Actin_micro PF17003.5 PVD18492.1 - 2.4 7.2 5.3 4.3 6.4 0.9 2.3 1 1 0 2 2 2 0 Putative actin-like family DZR PF12773.7 PVD18492.1 - 2.6 8.1 6.9 5 7.2 0.6 3.6 4 0 0 4 4 4 0 Double zinc ribbon zf-met PF12874.7 PVD18492.1 - 6.5 7.3 14.1 10 6.7 0.8 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Dicty_REP PF05086.12 PVD18495.1 - 0.17 9.9 10.9 0.2 9.6 10.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 PVD18495.1 - 0.48 10.2 8.2 0.64 9.8 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-H2C2_5 PF13909.6 PVD18497.1 - 1.4e-17 63.1 18.1 3.3e-08 33.1 1.5 4.3 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD18497.1 - 2.6e-15 55.9 27.2 3.7e-05 23.9 4.7 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD18497.1 - 6e-09 36.0 25.1 0.0026 18.4 0.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD18497.1 - 9.2e-08 32.2 28.9 2.8e-06 27.5 0.5 5.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-Di19 PF05605.12 PVD18497.1 - 9.1e-05 22.7 15.1 0.0047 17.2 3.8 2.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 PVD18497.1 - 0.055 13.5 2.2 1.4 9.0 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon Actin_micro PF17003.5 PVD18497.1 - 0.098 11.8 3.8 0.41 9.8 0.2 2.2 1 1 1 2 2 2 0 Putative actin-like family AKAP95 PF04988.12 PVD18497.1 - 0.14 12.4 7.1 0.31 11.2 0.1 2.5 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_9 PF16293.5 PVD18497.1 - 0.23 11.3 2.1 1 9.3 0.0 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 PVD18497.1 - 0.65 10.4 7.8 34 4.9 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 PVD18497.1 - 1 9.0 0.0 1 9.0 0.0 3.5 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 PVD18497.1 - 1.5 9.3 16.9 3.7 8.1 0.8 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type OrsD PF12013.8 PVD18497.1 - 1.6 9.2 13.3 1.2 9.6 0.3 3.4 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2HE PF16278.5 PVD18497.1 - 1.7 9.1 11.2 0.21 12.1 1.5 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 PVD18497.1 - 2.3 8.6 13.8 3.2 8.2 6.9 3.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 PVD18497.1 - 5.1 7.3 7.0 1.2 9.3 0.5 3.0 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 TTL PF03133.15 PVD18500.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Esterase PF00756.20 PVD18502.1 - 5.8e-41 140.8 0.0 8.8e-22 78.0 0.0 2.1 1 1 1 2 2 2 2 Putative esterase Esterase_phd PF10503.9 PVD18502.1 - 0.0035 16.9 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF2935 PF11155.8 PVD18503.1 - 0.022 15.1 0.4 2.8 8.3 0.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DNA_pol3_delt_C PF14840.6 PVD18503.1 - 0.08 13.3 0.3 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term NACHT_N PF17100.5 PVD18503.1 - 0.58 10.0 6.3 0.6 9.9 0.5 2.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Cep57_MT_bd PF06657.13 PVD18503.1 - 7.8 7.0 9.3 0.5 10.8 0.3 3.6 3 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Ank_2 PF12796.7 PVD18505.1 - 2.5e-16 60.0 0.2 2e-06 28.3 0.1 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD18505.1 - 3.7e-12 45.3 0.3 0.59 10.9 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PVD18505.1 - 6.8e-11 42.5 1.3 2.7e-05 24.6 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD18505.1 - 2.3e-10 40.5 0.8 6.3e-06 26.4 0.1 4.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD18505.1 - 1.3e-06 28.6 2.7 0.45 11.0 0.0 5.2 4 1 0 4 4 4 2 Ankyrin repeat p450 PF00067.22 PVD18506.1 - 1.3e-61 208.8 0.1 2.2e-58 198.1 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 Cyt_bd_oxida_I PF01654.17 PVD18506.1 - 0.099 11.2 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I GRP PF07172.11 PVD18507.1 - 0.24 12.1 0.0 0.27 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family DUF229 PF02995.17 PVD18509.1 - 1.9e-35 122.5 0.1 8.1e-35 120.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF229) DUF229 PF02995.17 PVD18510.1 - 3.7e-105 352.4 0.0 1.1e-104 350.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18510.1 - 0.0005 19.5 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD18510.1 - 0.001 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 PVD18512.1 - 3.9e-96 322.6 0.1 5e-48 163.9 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18512.1 - 7.9e-05 22.2 0.0 0.00027 20.4 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 PVD18512.1 - 0.0056 16.3 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Filamin PF00630.19 PVD18513.1 - 3.5e-86 284.7 0.0 6e-10 39.9 0.0 12.7 10 2 1 11 11 11 11 Filamin/ABP280 repeat Big_3_5 PF16640.5 PVD18513.1 - 2e-07 31.1 0.0 29 4.9 0.0 6.9 6 1 1 7 7 7 1 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 PVD18513.1 - 0.0001 22.6 0.0 37 4.7 0.0 6.8 7 2 0 7 7 7 0 Invasin, domain 3 tRNA_edit PF04073.15 PVD18513.1 - 0.003 17.6 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain DUF5060 PF16586.5 PVD18513.1 - 0.019 15.3 6.7 2.5 8.5 0.1 5.7 5 1 0 5 5 5 0 Domain of unknown function (DUF5060) YtkA PF13115.6 PVD18513.1 - 0.76 10.4 2.3 64 4.2 0.0 4.0 5 0 0 5 5 5 0 YtkA-like Ig_3 PF13927.6 PVD18514.1 - 3.3e-18 66.0 17.0 0.019 15.6 0.1 8.4 8 1 1 9 9 8 5 Immunoglobulin domain Ig_2 PF13895.6 PVD18514.1 - 6.2e-13 48.9 8.5 0.01 16.1 0.2 5.6 5 0 0 5 5 5 3 Immunoglobulin domain C1q PF00386.21 PVD18514.1 - 1.7e-11 44.4 6.1 2.4e-10 40.7 0.1 4.5 4 0 0 4 4 4 1 C1q domain I-set PF07679.16 PVD18514.1 - 6.7e-10 38.9 0.1 0.46 10.6 0.0 6.5 6 0 0 6 6 6 1 Immunoglobulin I-set domain DUF2046 PF09755.9 PVD18514.1 - 0.00048 19.5 10.1 0.0024 17.1 0.5 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein H4 (DUF2046) CASP_C PF08172.12 PVD18514.1 - 0.0012 18.3 4.4 0.022 14.1 1.2 2.2 2 0 0 2 2 2 1 CASP C terminal V-set PF07686.17 PVD18514.1 - 0.0017 18.5 7.9 0.11 12.6 0.1 5.7 7 0 0 7 7 6 1 Immunoglobulin V-set domain DUF4097 PF13349.6 PVD18514.1 - 0.02 14.2 0.2 6 6.1 0.0 3.2 4 0 0 4 4 4 0 Putative adhesin Ig_6 PF18452.1 PVD18514.1 - 0.084 12.5 2.1 34 4.1 0.0 4.0 4 0 0 4 4 3 0 Immunoglobulin domain Ig_GlcNase PF18368.1 PVD18514.1 - 0.092 12.9 0.1 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain KASH_CCD PF14662.6 PVD18514.1 - 0.11 12.4 7.8 0.83 9.5 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SAS4 PF15460.6 PVD18514.1 - 0.14 12.2 8.5 0.43 10.7 0.6 3.1 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 TPD52 PF04201.15 PVD18514.1 - 0.15 11.7 7.8 0.24 11.0 0.8 2.4 2 0 0 2 2 2 0 Tumour protein D52 family DASH_Dam1 PF08653.10 PVD18514.1 - 0.15 11.9 1.7 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 HAP1_N PF04849.13 PVD18514.1 - 0.16 11.2 8.2 1.3 8.1 1.0 2.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Tim29 PF10171.9 PVD18514.1 - 0.23 11.0 2.2 21 4.6 0.0 3.3 4 0 0 4 4 4 0 Translocase of the Inner Mitochondrial membrane 29 CENP-F_leu_zip PF10473.9 PVD18514.1 - 0.25 11.4 12.0 0.39 10.7 2.7 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-set_2 PF15910.5 PVD18514.1 - 0.35 11.0 1.8 1.3e+02 2.7 0.0 4.0 3 1 1 4 4 4 0 ICOS V-set domain YabA PF06156.13 PVD18514.1 - 0.5 11.0 8.7 3.9 8.2 1.2 2.7 2 0 0 2 2 2 0 Initiation control protein YabA PikAIV_N PF18605.1 PVD18514.1 - 1.2 8.8 15.8 0.82 9.3 1.9 3.4 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TSC22 PF01166.18 PVD18514.1 - 1.4 9.2 11.5 7.3 7.0 2.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 PVD18514.1 - 1.8 9.5 12.9 2 9.3 1.1 3.6 5 0 0 5 5 2 0 cGMP-dependent protein kinase interacting domain Geminin PF07412.12 PVD18514.1 - 2.3 7.9 9.7 0.62 9.8 3.1 2.3 2 0 0 2 2 2 0 Geminin ORF6C PF10552.9 PVD18514.1 - 2.8 8.0 8.6 0.96 9.6 0.0 3.2 3 0 0 3 3 3 0 ORF6C domain Prefoldin PF02996.17 PVD18514.1 - 3.7 7.5 7.2 0.96 9.4 0.0 2.9 3 0 0 3 3 2 0 Prefoldin subunit ZapB PF06005.12 PVD18514.1 - 7.8 7.0 18.6 0.28 11.7 3.3 3.1 3 0 0 3 3 2 0 Cell division protein ZapB bZIP_2 PF07716.15 PVD18514.1 - 8.5 6.6 17.5 4.3 7.5 7.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.8 PVD18514.1 - 9.4 5.5 8.0 16 4.7 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) C1q PF00386.21 PVD18515.1 - 4.1e-13 49.6 1.5 2.5e-12 47.1 0.4 2.3 2 0 0 2 2 2 1 C1q domain SH3_5 PF08460.10 PVD18515.1 - 0.0036 17.4 1.0 0.83 9.8 0.0 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain DUF4140 PF13600.6 PVD18515.1 - 0.011 16.1 2.2 0.21 12.0 1.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rootletin PF15035.6 PVD18515.1 - 0.033 14.2 5.6 0.28 11.2 3.2 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Hom_end_hint PF05203.16 PVD18515.1 - 0.042 13.8 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint MAD PF05557.13 PVD18515.1 - 0.093 11.1 7.3 0.74 8.1 3.6 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein KASH_CCD PF14662.6 PVD18515.1 - 0.17 11.7 12.4 2.3 8.0 5.0 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 PVD18515.1 - 0.28 11.6 16.5 0.81 10.2 7.6 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF4200 PF13863.6 PVD18515.1 - 0.44 10.9 12.0 0.044 14.2 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5320 PF17253.2 PVD18515.1 - 1.2 10.2 5.3 76 4.5 3.8 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Yuri_gagarin PF15934.5 PVD18515.1 - 1.3 8.9 8.8 1.2 9.0 3.3 2.2 2 0 0 2 2 2 0 Yuri gagarin DUF745 PF05335.13 PVD18515.1 - 1.4 8.6 6.9 0.072 12.8 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DivIC PF04977.15 PVD18515.1 - 2 8.2 13.3 2.1 8.2 1.4 3.1 2 1 1 3 3 3 0 Septum formation initiator GIT_CC PF16559.5 PVD18515.1 - 2.5 8.0 10.2 20 5.1 0.3 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 PVD18515.1 - 2.6 8.1 7.1 0.46 10.5 0.2 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 PVD18515.1 - 2.9 7.4 8.6 6.5 6.3 4.0 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DivIVA PF05103.13 PVD18515.1 - 5.3 7.1 14.0 0.19 11.8 6.2 2.0 2 0 0 2 2 2 0 DivIVA protein YabA PF06156.13 PVD18515.1 - 6.6 7.4 9.5 2.7 8.7 3.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 PVD18515.1 - 7.1 5.9 10.5 2.9 7.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) C1q PF00386.21 PVD18516.1 - 2e-16 60.3 1.4 4e-16 59.4 0.7 1.8 2 0 0 2 2 2 1 C1q domain Serpin PF00079.20 PVD18517.1 - 3.4e-30 105.6 0.0 1.6e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) C1q PF00386.21 PVD18517.1 - 1.1e-12 48.3 0.3 2.7e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 C1q domain Ig_2 PF13895.6 PVD18517.1 - 7.8e-05 22.9 0.7 0.0002 21.6 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 PVD18517.1 - 0.016 15.8 0.2 0.084 13.5 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain KLRAQ PF10205.9 PVD18517.1 - 0.018 15.2 1.7 0.034 14.4 1.7 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein ig PF00047.25 PVD18517.1 - 0.031 14.4 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain WEMBL PF05701.11 PVD18517.1 - 0.036 12.8 0.7 0.051 12.3 0.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light PPC PF04151.15 PVD18517.1 - 0.046 14.8 0.3 0.35 12.0 0.0 2.6 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Prefoldin PF02996.17 PVD18517.1 - 0.19 11.7 0.7 0.35 10.8 0.7 1.4 1 0 0 1 1 1 0 Prefoldin subunit TMF_DNA_bd PF12329.8 PVD18517.1 - 0.23 11.5 2.3 0.53 10.3 2.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0444 PF15475.6 PVD18518.1 - 0.053 13.8 6.0 72 3.8 0.0 6.9 2 1 10 12 12 12 0 Transmembrane protein C12orf23, UPF0444 UPF0180 PF03698.13 PVD18519.1 - 0.21 11.8 0.0 3.1 8.0 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0180) Borrelia_P13 PF05628.12 PVD18519.1 - 1.1 9.2 6.3 3.1 7.8 0.6 2.4 1 1 1 2 2 2 0 Borrelia membrane protein P13 C1q PF00386.21 PVD18520.1 - 1.4e-13 51.1 2.2 1.4e-12 48.0 1.4 2.2 2 0 0 2 2 2 1 C1q domain Ig_3 PF13927.6 PVD18520.1 - 0.00034 21.1 1.1 0.46 11.1 0.1 3.6 3 1 1 4 4 4 2 Immunoglobulin domain BclA_C PF18573.1 PVD18520.1 - 0.00085 19.2 1.1 0.0018 18.2 0.7 1.7 2 0 0 2 2 2 1 BclA C-terminal domain V-set PF07686.17 PVD18520.1 - 0.0048 17.0 1.5 0.074 13.2 0.1 3.1 1 1 2 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 PVD18520.1 - 0.0057 16.7 0.4 0.19 11.8 0.0 2.8 1 1 1 2 2 2 1 Immunoglobulin I-set domain PAP2_C PF14360.6 PVD18520.1 - 0.08 13.5 0.5 0.9 10.1 0.0 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal C1q PF00386.21 PVD18521.1 - 2e-10 40.9 7.0 3.6e-10 40.1 1.7 2.8 2 1 1 3 3 3 1 C1q domain Ig_2 PF13895.6 PVD18521.1 - 0.0018 18.6 5.4 0.016 15.6 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain CENP-F_leu_zip PF10473.9 PVD18521.1 - 0.03 14.3 3.1 0.053 13.6 3.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 PVD18521.1 - 0.12 13.0 0.7 0.28 11.8 0.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Cas9_REC PF16592.5 PVD18521.1 - 0.16 10.7 0.8 0.22 10.2 0.8 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 TPD52 PF04201.15 PVD18521.1 - 0.29 10.7 3.9 0.096 12.3 1.0 1.6 2 0 0 2 2 2 0 Tumour protein D52 family PikAIV_N PF18605.1 PVD18521.1 - 0.46 10.1 4.0 0.32 10.6 1.9 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Mto2_bdg PF12808.7 PVD18521.1 - 0.84 10.0 4.3 0.46 10.8 1.7 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ABC_membrane PF00664.23 PVD18522.1 - 4.5e-58 197.1 34.7 1.8e-37 129.5 18.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD18522.1 - 8.2e-38 130.0 1.9 1.6e-28 99.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 PVD18522.1 - 7.2e-07 28.9 2.8 0.0014 18.2 0.1 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PVD18522.1 - 6.5e-06 26.2 2.0 0.0034 17.3 0.5 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PVD18522.1 - 0.00028 20.6 2.1 0.62 9.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PVD18522.1 - 0.00093 19.3 0.5 0.82 9.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 PVD18522.1 - 0.022 13.7 3.0 0.43 9.5 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 PVD18522.1 - 0.051 12.7 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 PVD18522.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 PVD18522.1 - 0.18 12.1 2.7 4.7 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain UPF0093 PF03653.13 PVD18522.1 - 0.33 11.2 0.0 0.33 11.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) DUF87 PF01935.17 PVD18522.1 - 3.3 7.7 6.3 4.9 7.2 0.2 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain cNMP_binding PF00027.29 PVD18523.1 - 7.3e-16 58.0 0.0 3.7e-11 42.9 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 PVD18525.1 - 1.9e-08 34.2 0.1 4.5e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MFS_1 PF07690.16 PVD18527.1 - 5e-15 55.3 7.5 6.3e-15 54.9 7.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Gaa1 PF04114.14 PVD18527.1 - 0.014 14.4 0.5 0.019 14.0 0.5 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component zf-RING_14 PF17978.1 PVD18527.1 - 0.11 12.9 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.16 PVD18529.1 - 2.6e-19 69.4 9.2 6.2e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Claudin_2 PF13903.6 PVD18529.1 - 0.16 11.7 6.5 2.4 7.9 7.0 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MerR-DNA-bind PF09278.11 PVD18530.1 - 0.036 14.6 2.2 0.036 14.6 2.2 2.8 2 1 1 3 3 3 0 MerR, DNA binding DUF1192 PF06698.11 PVD18530.1 - 0.081 13.0 1.2 26 5.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LMBR1 PF04791.16 PVD18530.1 - 4.6 6.0 6.4 7.3 5.4 5.6 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein UBA PF00627.31 PVD18531.1 - 8.3e-11 41.6 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 PVD18531.1 - 0.0099 15.6 0.9 0.025 14.3 0.9 1.7 1 1 0 1 1 1 1 CUE domain Rab3-GTPase_cat PF13890.6 PVD18532.1 - 1.5e-64 216.6 0.5 3.2e-63 212.2 0.5 2.7 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit MutL_C PF08676.11 PVD18532.1 - 0.071 12.9 0.9 0.36 10.6 0.0 2.5 3 0 0 3 3 3 0 MutL C terminal dimerisation domain DUF2380 PF09533.10 PVD18532.1 - 0.076 12.6 0.1 2.1 7.9 0.1 2.5 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) zf-C3HC4 PF00097.25 PVD18533.1 - 7.7e-09 35.3 10.1 1.7e-08 34.2 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD18533.1 - 2.2e-07 30.6 10.5 4.1e-07 29.7 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD18533.1 - 8.6e-07 28.7 10.0 1.4e-06 28.0 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD18533.1 - 3.1e-06 27.1 8.2 6.8e-06 26.0 8.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD18533.1 - 6e-06 26.3 12.9 1.4e-05 25.1 12.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD18533.1 - 8.9e-05 22.3 11.2 0.00021 21.0 9.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 PVD18533.1 - 0.0016 18.5 1.4 0.0016 18.5 1.4 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 PVD18533.1 - 0.0019 18.5 12.5 0.0034 17.7 12.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD18533.1 - 0.0026 17.7 10.8 0.0059 16.5 10.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 PVD18533.1 - 0.026 14.3 13.1 0.041 13.7 10.6 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 PVD18533.1 - 0.054 13.4 3.1 0.11 12.4 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1644 PF07800.12 PVD18533.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1644) Tho2 PF11262.8 PVD18533.1 - 0.45 9.7 7.4 0.4 9.8 5.1 1.8 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RIX1 PF08167.12 PVD18534.1 - 1.1e-11 44.8 0.1 1.1e-11 44.8 0.1 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TFIIE-A_C PF11521.8 PVD18534.1 - 0.17 12.2 5.2 0.42 10.9 5.2 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha WD40 PF00400.32 PVD18537.1 - 5.4e-11 42.9 3.0 0.029 15.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18537.1 - 0.00037 20.7 0.0 0.66 10.3 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ICAT PF06384.11 PVD18537.1 - 0.0013 19.0 0.0 14 6.0 0.0 3.5 1 1 2 3 3 3 2 Beta-catenin-interacting protein ICAT eIF2A PF08662.11 PVD18537.1 - 0.0086 16.0 0.0 2.4 8.0 0.0 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF5544 PF17698.1 PVD18537.1 - 1.9 8.6 9.3 7.2 6.7 3.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5544) Sulfotransfer_2 PF03567.14 PVD18538.1 - 2.4e-39 135.8 5.3 3.4e-39 135.3 5.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family RNase_H2_suC PF08615.11 PVD18538.1 - 0.013 15.7 0.2 0.023 14.9 0.2 1.8 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Spot_14 PF07084.12 PVD18541.1 - 8.8e-32 110.4 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 LIM PF00412.22 PVD18542.1 - 1.3e-57 191.8 62.1 2.5e-14 53.2 2.6 5.1 5 0 0 5 5 5 5 LIM domain Epimerase PF01370.21 PVD18544.1 - 6.7e-20 71.6 0.0 9.1e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD18544.1 - 1.8e-17 63.3 0.0 2.3e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PVD18544.1 - 9.9e-11 41.9 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PVD18544.1 - 3.9e-10 39.6 0.0 5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PVD18544.1 - 7.4e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 PVD18544.1 - 5.4e-06 25.8 0.1 5.3e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 PVD18544.1 - 0.027 13.9 0.0 0.2 11.1 0.0 2.2 3 0 0 3 3 3 0 short chain dehydrogenase MTS PF05175.14 PVD18544.1 - 0.05 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RmlD_sub_bind PF04321.17 PVD18544.1 - 0.082 12.0 0.1 0.16 11.1 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 PVD18547.1 - 3e-20 72.7 0.0 4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD18547.1 - 5.9e-17 61.6 0.0 7.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PVD18547.1 - 1e-10 41.9 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PVD18547.1 - 1.2e-10 41.4 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PVD18547.1 - 9.8e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 PVD18547.1 - 5.1e-06 25.9 0.1 4.9e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 PVD18547.1 - 0.041 13.3 0.1 0.24 10.8 0.0 2.1 3 0 0 3 3 3 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 PVD18547.1 - 0.064 12.3 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain MTS PF05175.14 PVD18547.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 7tm_1 PF00001.21 PVD18548.1 - 6.6e-13 48.6 19.8 7.9e-13 48.3 19.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18548.1 - 2.9e-05 23.5 21.5 6.6e-05 22.3 21.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD18548.1 - 0.00029 20.6 21.8 0.0005 19.8 21.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD18548.1 - 0.00045 19.7 13.2 0.00062 19.2 13.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-C2HC_2 PF13913.6 PVD18548.1 - 0.21 11.6 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Ank_2 PF12796.7 PVD18549.1 - 4.7e-29 100.8 5.6 1.6e-10 41.4 0.7 5.0 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD18549.1 - 1.8e-23 81.9 15.1 1.1e-05 25.6 0.1 9.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 PVD18549.1 - 2.7e-22 78.8 5.2 6.5e-06 26.6 0.2 7.2 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD18549.1 - 4.8e-21 74.5 7.6 5.2e-07 29.8 0.0 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD18549.1 - 2e-19 67.6 10.9 0.00015 21.9 0.0 8.9 9 0 0 9 9 9 3 Ankyrin repeat 7tm_1 PF00001.21 PVD18549.1 - 0.0014 18.0 0.0 2 7.7 0.6 2.9 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD18550.1 - 9.2e-06 25.2 12.2 0.0019 17.6 4.9 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18550.1 - 6.1e-05 22.5 7.1 6.1e-05 22.5 7.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM40 PF15817.5 PVD18550.1 - 1.7 8.4 5.7 0.27 11.0 0.3 2.2 1 1 0 2 2 2 0 Transmembrane protein 40 family 7tm_1 PF00001.21 PVD18551.1 - 4.6e-08 32.7 14.6 0.0003 20.2 3.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18551.1 - 2.7e-05 23.6 6.4 2.7e-05 23.6 6.4 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM40 PF15817.5 PVD18551.1 - 4.3 7.1 7.0 0.19 11.5 0.2 2.2 2 1 1 3 3 3 0 Transmembrane protein 40 family zf-CCHC PF00098.23 PVD18552.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle 7tm_1 PF00001.21 PVD18552.1 - 0.046 13.0 4.2 0.48 9.7 1.1 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD18553.1 - 0.0001 21.7 8.1 0.00013 21.4 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cyt_bd_oxida_II PF02322.15 PVD18553.1 - 0.044 13.1 7.7 0.06 12.7 7.7 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II 7tm_1 PF00001.21 PVD18554.1 - 3.4e-08 33.1 18.3 7.2e-05 22.2 6.1 2.2 1 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18554.1 - 0.0085 15.4 17.5 0.012 14.9 4.9 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD18555.1 - 0.01 15.2 0.9 0.012 14.9 0.9 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD18556.1 - 1.3e-13 50.9 9.3 1.6e-13 50.6 9.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18556.1 - 0.00075 18.9 7.9 0.0044 16.3 7.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD18556.1 - 0.0026 17.2 1.0 0.0035 16.8 1.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD18557.1 - 2.7e-08 33.5 6.7 3.6e-08 33.1 6.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18557.1 - 3e-06 26.8 9.3 3.9e-06 26.4 9.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD18557.1 - 2.7e-05 23.7 3.7 3.5e-05 23.3 3.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rib_hydrolayse PF02267.17 PVD18558.1 - 1e-41 143.0 0.0 2.1e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosyl cyclase 7tm_1 PF00001.21 PVD18558.1 - 6.4e-17 61.7 23.5 6.4e-17 61.7 23.5 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD18558.1 - 1.1e-14 54.4 26.4 2.1e-14 53.6 26.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Rib_hydrolayse PF02267.17 PVD18559.1 - 1e-66 224.8 0.0 1.2e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Glyco_transf_22 PF03901.17 PVD18560.1 - 4.6e-43 148.0 13.9 1.3e-26 93.8 10.7 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family DUF2523 PF10734.9 PVD18560.1 - 0.079 13.5 1.2 0.72 10.5 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2523) KIAA1430 PF13879.6 PVD18561.1 - 1.3e-23 83.7 6.9 1.3e-23 83.7 6.9 3.1 2 1 0 2 2 2 1 KIAA1430 homologue Thymidylate_kin PF02223.17 PVD18561.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 2.2 2 1 1 3 3 3 1 Thymidylate kinase Pox_D2 PF04701.13 PVD18561.1 - 0.1 12.8 0.3 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 Pox virus D2 protein Myb_DNA-binding PF00249.31 PVD18562.1 - 3e-09 36.9 0.5 5.2e-07 29.8 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PVD18562.1 - 1.6e-07 31.1 0.7 0.0005 19.9 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PVD18562.1 - 4e-06 27.0 0.2 0.00025 21.3 0.0 2.6 2 1 0 2 2 2 1 Myb-like DNA-binding domain DUF4456 PF14644.6 PVD18562.1 - 0.0083 15.8 0.5 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) DHC_N2 PF08393.13 PVD18562.1 - 0.016 14.3 4.1 0.055 12.6 1.1 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 2 PEP-utilisers_N PF05524.13 PVD18562.1 - 0.022 14.9 1.2 4.1 7.6 0.0 2.5 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Gasdermin PF04598.12 PVD18562.1 - 0.029 13.8 4.8 0.061 12.7 0.4 2.3 1 1 1 2 2 2 0 Gasdermin pore forming domain Myb_DNA-bind_4 PF13837.6 PVD18562.1 - 0.05 14.0 2.6 2.6 8.5 0.6 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1664 PF07889.12 PVD18562.1 - 0.088 12.9 2.4 3.1 7.9 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Com_YlbF PF06133.11 PVD18562.1 - 0.11 13.1 2.6 0.26 11.9 2.2 2.0 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF4168 PF13767.6 PVD18562.1 - 0.17 13.0 3.6 1.8 9.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) CDH1_2_SANT_HL1 PF18375.1 PVD18562.1 - 0.29 11.8 1.9 16 6.2 0.4 3.0 2 1 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 CPSase_L_D2 PF02786.17 PVD18563.1 - 1.2e-57 194.9 1.0 3.6e-31 108.3 0.2 2.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PVD18563.1 - 9.1e-44 148.5 0.0 2.7e-43 147.0 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PVD18563.1 - 2.2e-24 85.6 0.0 7.2e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 PVD18563.1 - 8e-20 71.5 0.0 2.4e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 PVD18563.1 - 5.8e-15 54.9 3.2 1.6e-14 53.4 3.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PVD18563.1 - 4.8e-08 32.7 1.0 0.0011 18.7 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 PVD18563.1 - 2.3e-07 30.6 0.0 0.01 15.5 0.0 2.4 1 1 1 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp PF02222.22 PVD18563.1 - 8.4e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PVD18563.1 - 2e-06 27.5 0.1 0.0016 18.0 0.0 2.5 1 1 1 2 2 2 2 D-ala D-ala ligase C-terminus GARS_A PF01071.19 PVD18563.1 - 0.00018 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 PVD18563.1 - 0.011 16.4 1.0 0.94 10.2 0.1 3.2 2 1 1 3 3 3 0 HlyD family secretion protein AP_endonuc_2 PF01261.24 PVD18563.1 - 0.015 14.7 0.1 6 6.2 0.0 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel ATP-grasp_5 PF13549.6 PVD18563.1 - 0.015 14.7 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Oxidored_nitro PF00148.19 PVD18563.1 - 0.044 12.5 0.1 3.7 6.2 0.0 2.2 1 1 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ATP-grasp_3 PF02655.14 PVD18563.1 - 0.06 13.4 0.0 1.8 8.6 0.0 2.6 1 1 1 2 2 2 0 ATP-grasp domain Glyoxalase_4 PF13669.6 PVD18563.1 - 0.072 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UCH PF00443.29 PVD18564.1 - 5.5e-50 170.3 0.2 2.2e-49 168.3 0.2 2.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD18564.1 - 8.1e-25 88.1 7.4 3.6e-24 86.0 0.0 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CENP-O PF09496.10 PVD18564.1 - 0.1 12.6 1.2 4.2 7.3 0.3 2.9 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component FAST_1 PF06743.15 PVD18564.1 - 0.11 12.5 1.6 12 5.9 0.0 4.1 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 DUF1072 PF06380.11 PVD18564.1 - 0.27 11.1 2.7 0.73 9.8 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Mucin2_WxxW PF13330.6 PVD18565.1 - 9.7e-15 55.2 0.1 2.3e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region DUF456 PF04306.13 PVD18565.1 - 0.034 14.4 0.6 0.064 13.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Prefoldin_2 PF01920.20 PVD18566.1 - 0.0091 15.9 3.8 0.014 15.4 3.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit ATG16 PF08614.11 PVD18566.1 - 0.0097 16.2 6.7 0.013 15.7 6.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Transposase_22 PF02994.14 PVD18566.1 - 0.028 14.6 0.0 0.13 12.5 0.0 1.9 1 1 0 2 2 2 0 L1 transposable element RBD-like domain Syntaxin-6_N PF09177.11 PVD18566.1 - 0.056 14.0 2.5 0.069 13.7 1.8 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APS_kinase PF01583.20 PVD18566.1 - 0.07 13.0 1.3 0.37 10.7 0.2 2.1 1 1 1 2 2 2 0 Adenylylsulphate kinase GIT_CC PF16559.5 PVD18566.1 - 0.29 11.0 5.3 1.9 8.4 0.8 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 PVD18566.1 - 0.91 10.2 4.3 0.75 10.5 1.7 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Na_H_Exchanger PF00999.21 PVD18567.1 - 1.2e-76 258.0 33.9 3.2e-76 256.6 33.9 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family G_path_suppress PF15991.5 PVD18568.1 - 0.3 11.2 6.9 0.38 10.9 6.9 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Macoilin PF09726.9 PVD18568.1 - 0.67 8.5 3.5 0.74 8.3 3.5 1.0 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 PVD18568.1 - 1.9 6.4 3.9 2 6.3 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF885 PF05960.11 PVD18570.1 - 1.4e-71 242.8 0.0 1.7e-36 127.0 0.0 2.7 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF885) DUF1108 PF06531.11 PVD18570.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) REV1_C PF16727.5 PVD18570.1 - 0.3 11.5 1.0 9.4 6.7 0.0 3.5 4 0 0 4 4 4 0 DNA repair protein REV1 C-terminal domain DUF445 PF04286.12 PVD18571.1 - 0.077 12.8 0.5 0.59 9.9 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Peptidase_S8 PF00082.22 PVD18573.1 - 1.8e-86 290.1 0.0 2.6e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 PVD18573.1 - 1.1e-46 158.7 0.9 3.8e-46 157.0 0.9 1.9 1 1 0 1 1 1 1 Tripeptidyl peptidase II TPPII_N PF12583.8 PVD18573.1 - 2.6e-05 24.8 0.9 5.4e-05 23.8 0.9 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal VWA_2 PF13519.6 PVD18574.1 - 0.34 11.6 1.6 8.3 7.1 0.2 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain zf-MYND PF01753.18 PVD18575.1 - 1.6e-19 69.7 40.1 9e-11 41.7 12.7 2.9 2 1 0 2 2 2 2 MYND finger Ecl1 PF12855.7 PVD18575.1 - 5.2 8.2 15.9 0.29 12.3 0.5 3.0 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 PVD18575.1 - 5.6 7.4 33.3 0.66 10.3 5.5 3.7 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding RBP_receptor PF14752.6 PVD18576.1 - 3.9e-80 270.1 28.6 1.8e-63 215.1 20.4 3.0 1 1 1 2 2 2 2 Retinol binding protein receptor RBP_receptor PF14752.6 PVD18577.1 - 6.8e-46 157.1 10.2 3.2e-26 92.1 1.6 2.0 2 0 0 2 2 2 2 Retinol binding protein receptor RBP_receptor PF14752.6 PVD18578.1 - 1.3e-80 271.7 18.2 5.5e-47 160.7 7.7 2.1 1 1 1 2 2 2 2 Retinol binding protein receptor MFS_1 PF07690.16 PVD18579.1 - 2.9e-16 59.4 14.5 2.9e-16 59.4 14.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily PRA1 PF03208.19 PVD18581.1 - 0.27 10.9 9.7 0.39 10.3 9.7 1.1 1 0 0 1 1 1 0 PRA1 family protein MFS_1 PF07690.16 PVD18582.1 - 1.7e-23 83.1 48.3 1.3e-22 80.2 43.0 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 PVD18583.1 - 5.4e-11 42.0 42.4 4.8e-10 38.9 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 PVD18584.1 - 3.1e-55 182.9 20.2 2.9e-10 40.6 0.2 8.6 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18584.1 - 1.2e-13 51.1 0.3 0.27 11.6 0.1 6.5 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD18584.1 - 2.5e-08 33.6 0.1 0.52 9.6 0.0 5.3 2 2 3 5 5 5 3 WD40-like domain CEP19 PF14933.6 PVD18584.1 - 0.00015 22.1 0.1 0.00032 21.0 0.1 1.6 1 0 0 1 1 1 1 CEP19-like protein Nup160 PF11715.8 PVD18584.1 - 0.00048 18.9 2.4 4.6 5.8 0.0 4.9 2 1 4 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PVD18584.1 - 0.0068 15.4 6.1 1.3 7.9 0.4 4.4 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 PVD18584.1 - 0.04 12.2 0.0 0.21 9.8 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz MFS_1 PF07690.16 PVD18585.1 - 1.5e-27 96.4 62.4 3e-22 79.0 39.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily sCache_2 PF17200.4 PVD18585.1 - 0.25 11.2 0.0 3.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Single Cache domain 2 CBM_14 PF01607.24 PVD18586.1 - 2.2e-12 46.9 11.4 1.6e-06 28.2 3.3 2.9 1 1 1 2 2 2 2 Chitin binding Peritrophin-A domain SEA PF01390.20 PVD18586.1 - 7.3e-10 38.9 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SEA domain V-set PF07686.17 PVD18586.1 - 8.6e-08 32.3 0.0 0.0002 21.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD18586.1 - 0.0043 17.2 0.1 8.6 6.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD18586.1 - 0.023 14.7 0.1 5.2 7.2 0.0 3.3 3 1 0 3 3 3 0 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD18586.1 - 0.064 13.3 0.2 0.95 9.6 0.1 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain C1q PF00386.21 PVD18587.1 - 2.1e-15 57.1 1.2 4.7e-15 55.9 0.2 2.0 2 0 0 2 2 2 1 C1q domain Ig_3 PF13927.6 PVD18587.1 - 0.00013 22.5 0.0 0.46 11.1 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD18587.1 - 0.0002 21.5 0.1 0.0031 17.7 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 PVD18587.1 - 0.026 14.7 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 PVD18587.1 - 0.051 13.9 2.9 0.059 13.7 0.0 2.6 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 PVD18587.1 - 0.093 12.8 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain C1q PF00386.21 PVD18588.1 - 3.7e-20 72.4 0.4 1.9e-17 63.7 0.2 2.4 2 0 0 2 2 2 2 C1q domain zf-C2H2_4 PF13894.6 PVD18588.1 - 0.00053 20.6 0.5 0.00053 20.6 0.5 2.5 2 0 0 2 2 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD18588.1 - 0.02 15.3 0.7 0.02 15.3 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type YabA PF06156.13 PVD18588.1 - 0.023 15.3 2.0 0.052 14.2 2.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 PVD18588.1 - 0.029 14.4 4.5 0.075 13.1 4.5 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-H2C2_5 PF13909.6 PVD18588.1 - 0.049 13.4 0.4 0.1 12.3 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF1905 PF08922.11 PVD18588.1 - 0.073 13.1 0.0 3.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1905) Ig_2 PF13895.6 PVD18588.1 - 0.079 13.3 0.1 1.6 9.1 0.1 2.9 2 0 0 2 2 2 0 Immunoglobulin domain zf-C2H2_12 PF18658.1 PVD18588.1 - 0.084 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type HOOK PF05622.12 PVD18588.1 - 0.27 9.3 4.3 0.38 8.8 4.3 1.1 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.15 PVD18588.1 - 8.1 6.3 6.6 7 6.5 0.8 2.4 1 1 1 2 2 2 0 Septum formation initiator RRM_1 PF00076.22 PVD18589.1 - 4.3e-21 74.5 0.2 5.9e-21 74.1 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD18589.1 - 0.00029 20.9 0.1 0.00085 19.4 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD18589.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 PVD18589.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PVD18589.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 SOXp PF12336.8 PVD18596.1 - 3.1e-14 53.8 13.0 3.1e-14 53.8 13.0 2.7 1 1 1 2 2 2 1 SOX transcription factor ATF7IP_BD PF16788.5 PVD18604.1 - 0.049 13.7 0.7 0.052 13.6 0.7 1.0 1 0 0 1 1 1 0 ATF-interacting protein binding domain Lactamase_B PF00753.27 PVD18606.1 - 1.2e-16 61.3 4.9 8.5e-15 55.3 4.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PVD18606.1 - 0.00016 21.2 2.1 0.00078 19.0 2.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sulfotransfer_2 PF03567.14 PVD18607.1 - 7.2e-25 88.3 0.1 5.2e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD18608.1 - 1.5e-23 84.0 0.0 2.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Homeodomain PF00046.29 PVD18609.1 - 1.3e-23 82.6 3.6 2.3e-23 81.8 3.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD18609.1 - 0.00022 21.1 0.1 0.00052 19.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain 7tm_1 PF00001.21 PVD18610.1 - 3.6e-12 46.2 21.8 4.9e-12 45.7 21.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.6 PVD18610.1 - 0.095 12.9 4.2 6.5 7.0 0.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) S_4TM PF18159.1 PVD18610.1 - 1.2 8.4 5.4 0.16 11.2 0.4 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain CLU_N PF15044.6 PVD18611.1 - 0.00043 20.6 4.9 7.9 6.9 0.1 4.3 4 0 0 4 4 4 3 Mitochondrial function, CLU-N-term Cwf_Cwc_15 PF04889.12 PVD18611.1 - 0.0071 16.1 1.2 0.0095 15.7 1.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Semialdhyde_dh PF01118.24 PVD18611.1 - 0.093 13.2 1.1 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain CBM_14 PF01607.24 PVD18611.1 - 1.1 9.5 13.5 17 5.7 0.1 4.4 4 0 0 4 4 4 0 Chitin binding Peritrophin-A domain DIL PF01843.19 PVD18611.1 - 1.1 9.6 13.6 7.5 6.9 2.4 4.2 2 2 1 3 3 3 0 DIL domain Pkinase_Tyr PF07714.17 PVD18612.1 - 0.0015 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18612.1 - 0.0045 16.4 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M3 PF01432.20 PVD18613.1 - 7.8e-118 394.6 3.5 9.7e-118 394.3 3.5 1.1 1 0 0 1 1 1 1 Peptidase family M3 Atg14 PF10186.9 PVD18614.1 - 1.5e-11 44.0 0.1 2.6e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 PVD18614.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting 38 zf-C3HC4 PF00097.25 PVD18615.1 - 3.4e-10 39.6 6.0 5.2e-10 39.0 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD18615.1 - 1.1e-09 38.1 7.3 2.3e-09 37.1 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD18615.1 - 1.2e-08 35.1 6.9 1.7e-08 34.6 6.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD18615.1 - 7.7e-08 32.2 6.2 1.2e-07 31.6 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD18615.1 - 1e-07 31.7 5.3 1.7e-07 31.0 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD18615.1 - 8.5e-07 29.0 7.7 1.4e-06 28.3 7.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD18615.1 - 2.5e-06 27.2 9.7 8e-06 25.6 9.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD18615.1 - 3.5e-05 23.6 4.0 8.3e-05 22.4 4.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PVD18615.1 - 0.032 14.1 4.4 0.071 13.0 4.4 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 PVD18615.1 - 0.044 14.1 4.2 0.095 13.0 4.2 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD18615.1 - 0.19 11.5 4.1 0.41 10.4 4.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger Ephrin_rec_like PF07699.13 PVD18615.1 - 0.37 10.6 2.6 5.7 6.8 0.1 3.0 2 1 1 3 3 3 0 Putative ephrin-receptor like zf-RING_4 PF14570.6 PVD18615.1 - 1.1 9.1 6.3 4.1 7.3 6.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase_Tyr PF07714.17 PVD18616.1 - 6e-86 287.9 0.0 6.8e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18616.1 - 6.1e-45 153.6 0.0 6.9e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PVD18616.1 - 0.019 14.0 0.0 0.029 13.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PVD18616.1 - 0.095 12.0 0.1 0.25 10.6 0.1 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 PVD18616.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 PVD18617.1 - 5e-41 136.9 16.9 9.6e-07 28.4 0.8 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 PVD18617.1 - 7.3e-29 97.5 19.0 0.00021 21.1 0.1 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 PVD18617.1 - 3.6e-24 84.2 18.2 1.3e-06 28.0 0.8 7.5 3 3 5 8 8 8 5 TPR repeat TPR_8 PF13181.6 PVD18617.1 - 3.8e-24 82.8 15.1 2.5e-05 24.1 0.8 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 PVD18617.1 - 7.1e-22 77.8 2.7 4.2e-07 30.5 0.3 3.7 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD18617.1 - 9.9e-22 75.7 16.8 2.2e-05 24.5 0.7 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 PVD18617.1 - 2.2e-20 72.7 16.2 4.3e-07 30.1 1.7 5.0 3 2 2 5 5 4 3 Tetratricopeptide repeat DUF1736 PF08409.11 PVD18617.1 - 2.9e-20 72.0 5.2 7e-20 70.8 5.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_7 PF13176.6 PVD18617.1 - 3.3e-15 54.9 10.9 0.22 11.7 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 PVD18617.1 - 4.1e-14 51.9 13.7 4.4e-05 23.2 0.2 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD18617.1 - 9.3e-13 47.8 8.3 0.13 13.1 0.0 7.0 2 1 5 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD18617.1 - 6.9e-11 42.5 13.4 0.00018 21.9 0.6 5.2 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 PVD18617.1 - 9e-08 32.2 6.4 0.28 11.4 0.2 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 PVD18617.1 - 4.8e-07 29.3 9.5 8.3e-06 25.2 9.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 PVD18617.1 - 1.6e-06 27.4 4.6 0.0059 15.6 0.5 2.2 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 PVD18617.1 - 0.00029 20.4 0.6 0.87 8.9 0.0 2.7 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_6 PF13174.6 PVD18617.1 - 0.00031 21.2 12.3 6 7.7 0.0 6.9 5 2 0 6 6 6 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 PVD18617.1 - 0.0076 15.8 1.3 0.034 13.6 0.3 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_4 PF07721.14 PVD18617.1 - 0.05 14.2 0.2 53 4.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 PVD18617.1 - 0.12 11.8 3.2 0.16 11.4 0.1 2.7 3 0 0 3 3 3 0 SHNi-TPR TPR_20 PF14561.6 PVD18617.1 - 0.44 10.9 6.9 8.4 6.8 1.8 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD18617.1 - 1.2 9.2 6.5 33 4.7 1.3 3.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 PVD18617.1 - 1.7 9.0 7.2 26 5.2 0.8 3.1 1 1 3 4 4 4 0 Bacterial transcriptional activator domain YfhO PF09586.10 PVD18617.1 - 2.2 6.4 5.9 3.4 5.8 5.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Serpin PF00079.20 PVD18618.1 - 4.4e-32 111.8 0.0 5.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Coat_F PF07875.12 PVD18618.1 - 0.12 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Coat F domain Spore_IV_A PF09547.10 PVD18619.1 - 0.25 10.2 1.6 0.36 9.7 1.6 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) CC2-LZ PF16516.5 PVD18619.1 - 0.5 10.8 11.0 0.14 12.5 4.1 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AATF-Che1 PF13339.6 PVD18619.1 - 0.58 10.8 7.0 0.67 10.6 0.9 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4164 PF13747.6 PVD18619.1 - 3.9 7.8 10.4 0.93 9.8 5.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.20 PVD18619.1 - 6.7 6.7 11.9 10 6.2 4.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit NDK PF00334.19 PVD18620.1 - 9.8e-65 216.6 0.0 2.9e-44 150.4 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 PVD18620.1 - 0.024 14.5 0.3 0.096 12.5 0.3 2.0 1 1 0 1 1 1 0 DUF1126 PH-like domain DEAD PF00270.29 PVD18621.1 - 3.5e-51 173.5 0.0 4.4e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD18621.1 - 5.5e-14 52.5 0.0 9.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD18621.1 - 6.4e-05 23.0 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF780 PF05611.11 PVD18622.1 - 0.95 10.3 20.2 2.1 9.1 20.2 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) PNMA PF14893.6 PVD18623.1 - 0.0051 16.3 0.4 0.0059 16.0 0.4 1.2 1 0 0 1 1 1 1 PNMA Rbsn PF11464.8 PVD18623.1 - 0.058 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain ATG101 PF07855.12 PVD18623.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 101 RB_A PF01858.17 PVD18624.1 - 4.9e-63 212.5 3.4 6.2e-63 212.2 0.3 2.7 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 PVD18624.1 - 1.6e-35 122.0 6.6 8.3e-35 119.7 6.6 2.3 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 PVD18624.1 - 5.8e-18 64.8 5.1 2e-17 63.0 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3452) PSDC PF12588.8 PVD18624.1 - 0.14 12.2 0.0 24 4.9 0.0 3.4 3 0 0 3 3 3 0 Phophatidylserine decarboxylase DUF229 PF02995.17 PVD18625.1 - 5e-76 256.3 2.6 5e-76 256.3 2.6 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD18625.1 - 1.3e-05 24.8 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD18625.1 - 0.00043 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PBD PF00786.28 PVD18626.1 - 1e-26 93.0 0.1 2.3e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain DASH_Dad2 PF08654.10 PVD18626.1 - 0.066 13.6 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 Pkinase PF00069.25 PVD18627.1 - 9e-63 212.1 0.0 2e-54 184.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18627.1 - 2.4e-36 125.3 0.1 2.7e-33 115.3 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD18627.1 - 9.1e-08 31.3 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD18627.1 - 6.3e-05 22.4 0.0 0.00019 20.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 PVD18627.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PVD18627.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DSHCT PF08148.12 PVD18627.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 PVD18627.1 - 0.041 13.2 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD18627.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MFS_1 PF07690.16 PVD18628.1 - 6.7e-21 74.6 8.2 3.2e-17 62.5 0.0 3.5 4 0 0 4 4 4 3 Major Facilitator Superfamily DUF445 PF04286.12 PVD18629.1 - 0.029 14.2 0.1 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Rhabdo_glycop PF00974.18 PVD18629.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein F420_oxidored PF03807.17 PVD18630.1 - 6e-11 42.8 0.0 3.1e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PVD18630.1 - 1.5e-05 24.5 0.0 3.8e-05 23.1 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ferric_reduct PF01794.19 PVD18630.1 - 1.6e-05 25.0 8.5 0.00019 21.5 1.6 2.6 1 1 1 2 2 2 2 Ferric reductase like transmembrane component Shikimate_DH PF01488.20 PVD18630.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 PVD18630.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ATG16 PF08614.11 PVD18631.1 - 1.4e-37 129.9 13.6 2e-37 129.4 13.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 PVD18631.1 - 2.2e-19 69.4 7.5 8.2e-06 26.5 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18631.1 - 0.00027 21.2 0.1 0.0082 16.4 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ChaB PF06150.12 PVD18631.1 - 0.012 16.2 0.3 0.028 15.0 0.3 1.6 1 0 0 1 1 1 0 ChaB DUF724 PF05266.14 PVD18631.1 - 0.022 14.6 9.1 0.021 14.7 8.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Nup160 PF11715.8 PVD18631.1 - 0.036 12.7 2.1 0.79 8.3 0.3 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 V_ATPase_I PF01496.19 PVD18631.1 - 0.047 11.6 6.8 0.063 11.2 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 PVD18631.1 - 0.073 13.1 18.3 0.5 10.4 7.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding KASH_CCD PF14662.6 PVD18631.1 - 0.11 12.4 17.8 0.049 13.4 5.9 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 PVD18631.1 - 0.31 10.4 7.5 0.49 9.7 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 PVD18631.1 - 0.42 11.5 15.2 0.041 14.8 10.0 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 PVD18631.1 - 0.51 10.8 11.3 0.95 9.9 11.3 1.4 1 0 0 1 1 1 0 Fez1 DUF4472 PF14739.6 PVD18631.1 - 1.2 9.9 14.4 0.62 10.8 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Cep57_MT_bd PF06657.13 PVD18631.1 - 2.4 8.6 12.9 6.8 7.2 1.7 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 PVD18631.1 - 3 8.0 8.6 5.9 7.1 8.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 PVD18631.1 - 4 6.7 8.0 6.9 5.9 8.0 1.4 1 0 0 1 1 1 0 FAM76 protein CENP-H PF05837.12 PVD18631.1 - 5.1 7.5 16.3 2.9 8.3 9.9 2.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 PVD18631.1 - 7.7 6.7 15.3 4.2 7.6 5.2 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Aminotran_5 PF00266.19 PVD18632.1 - 4.3e-47 160.8 0.0 2e-46 158.7 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V AAA_12 PF13087.6 PVD18632.1 - 3.7e-34 118.1 0.0 9e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD18632.1 - 1.1e-29 104.1 0.1 1.2e-28 100.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain SH2 PF00017.24 PVD18632.1 - 1.1e-13 51.1 0.0 3.3e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain AAA_19 PF13245.6 PVD18632.1 - 1.3e-07 32.1 0.2 3.2e-06 27.6 0.1 3.2 3 1 0 3 3 2 1 AAA domain Exo_endo_phos PF03372.23 PVD18632.1 - 1.8e-07 30.9 0.0 4.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_30 PF13604.6 PVD18632.1 - 2.1e-06 27.6 0.1 0.0071 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PVD18632.1 - 0.00014 22.2 0.6 0.0022 18.3 0.0 3.0 2 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 PVD18632.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 PVD18632.1 - 0.0023 17.5 0.1 0.011 15.3 0.1 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 PVD18632.1 - 0.0052 16.4 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PVD18632.1 - 0.0079 16.2 0.2 0.098 12.6 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 PVD18632.1 - 0.024 14.1 0.2 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 PVD18632.1 - 0.14 12.6 0.0 4.7 7.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Remorin_C PF03763.13 PVD18632.1 - 3.8 7.4 4.3 12 5.8 0.4 2.9 2 0 0 2 2 2 0 Remorin, C-terminal region TCTP PF00838.17 PVD18633.1 - 2.4e-43 148.3 0.5 2.9e-43 148.1 0.5 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Cullin PF00888.22 PVD18634.1 - 3.4e-157 524.8 9.6 1.8e-153 512.4 6.8 2.0 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 PVD18634.1 - 1.4e-06 28.2 0.1 8e-06 25.8 0.1 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain OSCP PF00213.18 PVD18634.1 - 0.011 15.9 4.9 0.78 9.9 0.2 2.8 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit PTPA PF03095.15 PVD18634.1 - 0.1 12.0 0.7 0.21 11.0 0.7 1.6 1 1 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF5071 PF16804.5 PVD18634.1 - 0.54 10.5 3.7 7.3 6.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Nnf1 PF03980.14 PVD18634.1 - 0.71 10.3 6.1 0.93 9.9 3.3 2.4 2 0 0 2 2 2 0 Nnf1 DUF2018 PF09442.10 PVD18634.1 - 6.9 7.7 6.0 2 9.4 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF2018) Smg4_UPF3 PF03467.15 PVD18635.1 - 6.6e-56 189.1 2.4 6.6e-56 189.1 2.4 3.3 4 1 0 4 4 4 1 Smg-4/UPF3 family RhoGEF PF00621.20 PVD18636.1 - 5.3e-39 134.3 2.7 5.3e-39 134.3 2.7 2.9 3 0 0 3 3 3 1 RhoGEF domain SH3_1 PF00018.28 PVD18636.1 - 8.3e-12 44.5 2.3 1e-11 44.2 0.1 2.4 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 PVD18636.1 - 1.8e-09 37.3 0.3 1.8e-09 37.3 0.3 2.7 3 0 0 3 3 3 1 Variant SH3 domain CRAL_TRIO_2 PF13716.6 PVD18636.1 - 1e-08 35.5 0.0 2.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SH3_2 PF07653.17 PVD18636.1 - 6.9e-08 32.1 0.0 1.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 PVD18636.1 - 3.3e-06 27.6 0.9 1e-05 26.0 0.9 1.9 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 PVD18636.1 - 0.00028 21.1 0.3 0.00068 19.9 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RNase_HII PF01351.18 PVD18636.1 - 0.045 13.6 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease HII CRAL_TRIO PF00650.20 PVD18636.1 - 0.048 13.4 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 CRAL/TRIO domain Spectrin PF00435.21 PVD18636.1 - 0.069 13.6 12.3 0.59 10.6 2.4 3.8 3 0 0 3 3 3 0 Spectrin repeat DUF2384 PF09722.10 PVD18636.1 - 0.083 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) SH3_3 PF08239.11 PVD18636.1 - 0.16 12.2 3.0 0.12 12.6 0.9 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain Tctex-1 PF03645.13 PVD18638.1 - 3.9e-27 94.5 0.7 4.9e-27 94.2 0.7 1.1 1 0 0 1 1 1 1 Tctex-1 family ANAPC4_WD40 PF12894.7 PVD18640.1 - 4.6e-09 36.5 0.4 0.084 13.2 0.0 5.6 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD18640.1 - 1.1e-06 29.2 6.1 1.1 10.3 0.0 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 PVD18640.1 - 0.019 14.8 0.4 3.6 7.4 0.0 3.5 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD18640.1 - 0.021 13.8 0.0 5.2 5.9 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FUN14 PF04930.15 PVD18640.1 - 0.033 14.6 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 FUN14 family Coatomer_WDAD PF04053.14 PVD18640.1 - 0.091 11.8 1.8 3.2 6.7 0.0 3.4 3 1 0 4 4 4 0 Coatomer WD associated region zf-CCCH PF00642.24 PVD18642.1 - 0.00019 21.2 4.2 0.007 16.3 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PVD18642.1 - 0.096 12.9 1.6 4.2 7.6 2.2 2.3 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PVD18642.1 - 0.15 12.6 8.4 1.1 9.8 0.9 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger YkpC PF17447.2 PVD18644.1 - 0.26 12.2 1.3 1.1 10.2 1.3 2.1 1 0 0 1 1 1 0 Uncharacterized YkpC-like zf-CCCH_4 PF18044.1 PVD18646.1 - 0.053 13.3 3.3 0.25 11.2 3.3 2.1 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 PVD18646.1 - 2.2 8.3 9.8 0.53 10.3 4.4 2.6 2 2 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PCC_BT PF18140.1 PVD18648.1 - 8.7e-05 22.9 0.1 0.00029 21.2 0.1 1.8 1 1 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain T2SSN PF01203.19 PVD18648.1 - 0.0056 16.9 2.7 0.39 10.9 1.2 2.3 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein N IL3Ra_N PF18611.1 PVD18648.1 - 0.0061 16.5 2.6 10 6.2 0.2 3.9 1 1 2 3 3 3 1 IL-3 receptor alpha chain N-terminal domain Peptidase_C36 PF05415.11 PVD18648.1 - 0.009 16.2 0.3 47 4.3 0.1 3.5 1 1 3 4 4 4 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase INPP5B_PH PF16776.5 PVD18648.1 - 0.012 15.3 0.0 4.4 7.0 0.0 2.7 1 1 1 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain TOBE_3 PF12857.7 PVD18648.1 - 0.017 15.0 0.2 8.4 6.4 0.1 3.7 1 1 2 3 3 3 0 TOBE-like domain GARS_A PF01071.19 PVD18648.1 - 0.043 13.6 2.8 0.17 11.7 0.3 2.0 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KH_4 PF13083.6 PVD18648.1 - 0.063 13.2 0.1 15 5.6 0.1 3.0 1 1 2 3 3 3 0 KH domain DUF5462 PF17547.2 PVD18648.1 - 0.076 12.4 0.3 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5462) HCV_env PF01539.17 PVD18652.1 - 0.0044 16.7 11.3 2.5 7.7 0.3 3.6 1 1 3 4 4 4 4 Hepatitis C virus envelope glycoprotein E1 TipAS PF07739.13 PVD18652.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Cys_knot PF00007.22 PVD18652.1 - 0.92 9.8 16.4 0.13 12.6 5.4 3.1 1 1 2 3 3 3 0 Cystine-knot domain MgtE_N PF03448.17 PVD18654.1 - 0.00018 22.1 0.0 0.21 12.2 0.0 2.3 1 1 1 2 2 2 2 MgtE intracellular N domain CRISPR_Cas2 PF09827.9 PVD18654.1 - 0.0028 17.8 32.7 34 4.7 0.3 10.1 1 1 5 6 6 6 4 CRISPR associated protein Cas2 Pro_Al_protease PF02983.14 PVD18654.1 - 0.052 13.6 11.2 8 6.6 0.2 5.1 3 2 2 5 5 5 0 Alpha-lytic protease prodomain FidL_like PF15941.5 PVD18654.1 - 3.3 8.2 20.7 8.3 6.9 1.4 4.1 1 1 3 4 4 4 0 FidL-like putative membrane protein ATP-grasp_2 PF08442.10 PVD18655.1 - 1.2e-67 227.4 0.7 1.8e-67 226.8 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 PVD18655.1 - 2.5e-26 92.3 2.6 4.1e-26 91.6 2.6 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 PVD18655.1 - 9.4e-10 38.3 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 PVD18655.1 - 0.0077 16.0 0.3 0.022 14.5 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Profilin PF00235.19 PVD18656.1 - 3.7e-23 82.2 0.1 4.1e-23 82.0 0.1 1.0 1 0 0 1 1 1 1 Profilin STAT1_TAZ2bind PF12162.8 PVD18656.1 - 0.0064 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain TFIIF_beta PF02270.15 PVD18657.1 - 4.3e-24 84.4 0.1 7.9e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 PVD18657.1 - 1.7e-18 67.6 0.9 8.2e-17 62.2 0.0 2.6 2 1 1 3 3 3 1 TFIIF, beta subunit N-terminus Rep_fac_C PF08542.11 PVD18658.1 - 3e-19 69.2 1.5 1.5e-18 67.0 0.3 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 PVD18658.1 - 1.2e-16 61.3 0.0 3.3e-16 59.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PVD18658.1 - 6.6e-13 48.8 0.0 5.3e-11 42.6 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 PVD18658.1 - 1.5e-06 28.7 0.0 0.00023 21.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 PVD18658.1 - 1.4e-05 24.9 0.0 5.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PVD18658.1 - 1.9e-05 24.7 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 PVD18658.1 - 4.5e-05 23.3 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 PVD18658.1 - 4.8e-05 23.6 0.1 0.00018 21.8 0.1 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 PVD18658.1 - 0.00026 20.9 0.0 0.00046 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD18658.1 - 0.00037 20.8 0.0 0.026 14.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD18658.1 - 0.0018 18.6 0.1 0.052 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 PVD18658.1 - 0.004 16.3 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 PVD18658.1 - 0.0069 16.2 0.1 0.071 12.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 PVD18658.1 - 0.0069 15.7 0.0 0.034 13.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 PVD18658.1 - 0.01 15.3 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI F-box-like_2 PF13013.6 PVD18658.1 - 0.012 15.6 0.1 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain AAA_5 PF07728.14 PVD18658.1 - 0.013 15.5 0.0 0.066 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 PVD18658.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ATPase_2 PF01637.18 PVD18658.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PVD18658.1 - 0.064 12.8 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region Kinesin PF00225.23 PVD18658.1 - 0.071 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_3 PF07726.11 PVD18658.1 - 0.072 13.0 0.1 0.38 10.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 PVD18658.1 - 0.079 12.7 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 PVD18658.1 - 0.095 12.5 0.2 3 7.6 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase Pkinase PF00069.25 PVD18659.1 - 1.1e-69 234.8 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18659.1 - 4e-35 121.3 0.0 5.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD18659.1 - 6.2e-08 32.3 0.1 4.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PVD18659.1 - 0.03 14.2 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD18659.1 - 0.12 11.3 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Med4 PF10018.9 PVD18660.1 - 3.5e-29 101.9 1.8 4.2e-29 101.6 1.8 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HMMR_N PF15905.5 PVD18660.1 - 0.0057 16.2 4.3 0.0091 15.5 4.3 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF641 PF04859.12 PVD18660.1 - 0.011 16.0 2.4 0.046 14.1 1.9 2.2 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Siah-Interact_N PF09032.11 PVD18660.1 - 0.39 11.1 6.6 1.7 9.0 6.6 2.2 1 1 0 1 1 1 0 Siah interacting protein, N terminal Seryl_tRNA_N PF02403.22 PVD18660.1 - 0.48 10.7 7.3 0.8 10.0 7.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Dehydrin PF00257.19 PVD18660.1 - 9.5 6.7 9.2 5.3 7.6 6.6 1.7 1 1 1 2 2 2 0 Dehydrin AAA_30 PF13604.6 PVD18661.1 - 1.5e-05 24.8 0.0 7.1e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD18661.1 - 0.0098 16.3 0.0 0.032 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 PVD18661.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD18661.1 - 0.067 13.5 0.0 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PVD18661.1 - 0.093 12.3 0.2 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PQ-loop PF04193.14 PVD18663.1 - 0.00011 21.9 0.3 0.00019 21.1 0.3 1.5 1 0 0 1 1 1 1 PQ loop repeat Cyclin_N PF00134.23 PVD18665.1 - 1.6e-33 115.1 0.3 1.6e-33 115.1 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PVD18665.1 - 1.3e-23 83.3 0.1 3.7e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4614 PF15391.6 PVD18666.1 - 5 7.1 17.8 13 5.7 14.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 PVD18666.1 - 5.8 5.6 9.3 7 5.3 9.3 1.1 1 0 0 1 1 1 0 Presenilin Sec34 PF04136.15 PVD18667.1 - 0.19 11.6 5.0 0.49 10.3 1.1 2.0 1 1 1 2 2 2 0 Sec34-like family DsbG_N PF18257.1 PVD18667.1 - 0.84 9.8 11.7 0.23 11.6 0.7 3.3 1 1 3 4 4 4 0 Disulfide isomerase DsbG N-terminal DUF1664 PF07889.12 PVD18667.1 - 6.3 6.9 7.7 16 5.6 7.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 PVD18667.1 - 6.7 5.9 18.2 3.8 6.7 9.3 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein HSP70 PF00012.20 PVD18667.1 - 10 4.2 16.0 12 4.0 16.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Sec34 PF04136.15 PVD18668.1 - 0.42 10.5 6.6 0.37 10.7 1.8 2.3 1 1 2 3 3 3 0 Sec34-like family RmuC PF02646.16 PVD18668.1 - 0.44 9.6 12.9 1.6 7.8 4.5 2.6 1 1 2 3 3 3 0 RmuC family DsbG_N PF18257.1 PVD18668.1 - 1.2 9.3 14.9 0.41 10.8 0.7 3.8 1 1 2 4 4 4 0 Disulfide isomerase DsbG N-terminal ISG65-75 PF11727.8 PVD18668.1 - 7.1 5.8 19.8 1.6 7.9 7.9 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein C2 PF00168.30 PVD18669.1 - 5.1e-06 26.7 0.0 6.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 PVD18670.1 - 5.4e-25 88.2 17.1 2.8e-24 85.8 17.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD18670.1 - 4e-22 78.6 14.0 1.8e-21 76.5 14.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 PVD18670.1 - 1.7e-05 23.6 16.8 3.3e-05 22.7 6.6 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein I-set PF07679.16 PVD18673.1 - 2e-48 162.4 0.1 3.5e-13 49.4 0.1 4.4 3 1 1 4 4 4 4 Immunoglobulin I-set domain Ribosomal_S8e PF01201.22 PVD18673.1 - 7.4e-44 149.2 16.6 2.1e-43 147.8 15.0 2.5 1 1 0 1 1 1 1 Ribosomal protein S8e Ig_3 PF13927.6 PVD18673.1 - 5.2e-40 135.9 2.7 1.2e-12 48.2 0.1 4.6 3 1 1 4 4 4 4 Immunoglobulin domain ig PF00047.25 PVD18673.1 - 8.1e-36 122.1 8.8 8.7e-10 38.6 0.1 6.2 5 2 1 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 PVD18673.1 - 5.1e-24 84.4 0.6 1.5e-06 28.4 0.0 4.6 3 1 1 4 4 4 4 Immunoglobulin domain V-set PF07686.17 PVD18673.1 - 6.2e-20 71.4 3.6 0.00059 20.0 0.0 5.9 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD18673.1 - 8.5e-07 28.4 0.0 0.83 9.3 0.0 4.4 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD18673.1 - 1.1e-05 25.4 0.0 0.19 11.8 0.0 4.1 3 1 1 4 4 4 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD18673.1 - 0.00018 21.5 0.5 0.54 10.4 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 PVD18673.1 - 0.0025 17.8 0.1 0.21 11.6 0.0 3.1 2 1 1 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 PVD18673.1 - 0.0083 16.4 2.3 0.6 10.4 0.0 4.1 5 0 0 5 5 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 PVD18673.1 - 0.0096 15.9 0.0 0.88 9.7 0.0 3.4 3 1 1 4 4 4 1 C17orf99 Ig domain Herpes_gE PF02480.16 PVD18673.1 - 0.043 12.6 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4232 PF14016.6 PVD18673.1 - 0.096 12.8 1.1 0.44 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) MFS_1 PF07690.16 PVD18674.1 - 5.1e-34 117.7 8.0 5.1e-34 117.7 8.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD18674.1 - 9.1e-31 107.2 16.4 4.1e-25 88.5 6.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD18674.1 - 1.5e-06 27.0 8.4 1.5e-06 27.0 8.4 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4495 PF14906.6 PVD18675.1 - 3.8e-97 325.2 10.3 3.8e-97 325.2 10.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4495) LAGLIDADG_2 PF03161.13 PVD18675.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Phage_prot_Gp6 PF05133.14 PVD18675.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like EF-hand_7 PF13499.6 PVD18676.1 - 6.1e-10 39.4 10.7 9.1e-05 22.8 0.3 4.5 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 PVD18676.1 - 1.6e-09 36.6 11.0 0.012 15.1 0.0 6.5 6 1 1 7 7 7 3 EF hand 7tm_1 PF00001.21 PVD18676.1 - 2.7e-07 30.2 13.0 2.1e-05 24.0 9.3 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) EF-hand_6 PF13405.6 PVD18676.1 - 9e-07 28.3 15.8 0.16 12.0 0.0 6.5 6 1 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.6 PVD18676.1 - 2e-05 23.8 16.2 0.045 13.3 0.1 6.6 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 PVD18676.1 - 0.11 12.4 10.9 8.4 6.3 0.1 5.1 5 0 0 5 5 5 0 EF-hand domain pair CTK3_C PF12350.8 PVD18676.1 - 1.8 8.8 3.9 5 7.3 0.3 2.9 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 C-terminus Dockerin_1 PF00404.18 PVD18676.1 - 3.2 8.0 9.8 32 4.8 0.0 4.6 3 2 3 6 6 6 0 Dockerin type I domain EF-hand_4 PF12763.7 PVD18676.1 - 7.9 6.5 6.2 52 3.9 0.2 3.3 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Pkinase_Tyr PF07714.17 PVD18677.1 - 3.3e-50 170.8 0.0 3.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18677.1 - 3.2e-22 79.2 0.0 4.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PVD18677.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 PVD18678.1 - 3.9e-21 75.5 0.0 5.2e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18678.1 - 3.5e-13 49.5 0.0 4.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Osw5 PF17062.5 PVD18678.1 - 0.16 12.1 0.2 0.16 12.1 0.2 1.6 2 0 0 2 2 2 0 Outer spore wall 5 LRR_8 PF13855.6 PVD18679.1 - 2.5e-10 40.0 6.6 2.9e-06 26.9 0.7 2.2 1 1 1 2 2 2 2 Leucine rich repeat Ig_3 PF13927.6 PVD18679.1 - 2.3e-09 37.7 0.7 0.00012 22.7 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD18679.1 - 5.6e-07 29.6 0.0 0.00021 21.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain LRR_4 PF12799.7 PVD18679.1 - 3.4e-05 24.1 0.9 0.00061 20.1 0.3 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) TPKR_C2 PF16920.5 PVD18679.1 - 0.0001 22.4 1.2 0.00041 20.4 1.2 2.2 1 1 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain ig PF00047.25 PVD18679.1 - 0.022 14.9 0.1 0.44 10.8 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain LRR_9 PF14580.6 PVD18679.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 PVD18679.1 - 0.17 12.0 1.7 28 5.1 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 PVD18679.1 - 0.41 11.4 4.2 3.8 8.4 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat RT_RNaseH PF17917.1 PVD18680.1 - 3.6e-31 107.6 0.0 4.3e-29 100.9 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PVD18680.1 - 1.5e-27 95.5 0.0 7.6e-24 83.6 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Beta_lactamase3 PF17030.5 PVD18680.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family Collagen PF01391.18 PVD18685.1 - 8.9e-06 25.4 3.0 0.0011 18.7 0.9 2.8 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Asp_Arg_Hydrox PF05118.15 PVD18685.1 - 0.39 10.5 1.7 44 3.9 0.0 3.4 3 1 1 4 4 4 0 Aspartyl/Asparaginyl beta-hydroxylase CBM_14 PF01607.24 PVD18686.1 - 2.9e-08 33.8 2.4 5.7e-08 32.8 2.4 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain IFT81_CH PF18383.1 PVD18687.1 - 5.3e-52 175.3 1.3 5.3e-52 175.3 1.3 2.9 2 1 2 4 4 4 1 Intraflagellar transport 81 calponin homology domain Ndc80_HEC PF03801.13 PVD18687.1 - 0.58 9.8 4.3 0.22 11.2 0.1 2.4 3 0 0 3 3 3 0 HEC/Ndc80p family MtrG PF04210.13 PVD18687.1 - 1.5 8.8 3.7 39 4.2 0.1 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G TetR_C_13 PF16925.5 PVD18687.1 - 1.6 8.7 6.8 0.44 10.5 2.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Activator-TraM PF11657.8 PVD18687.1 - 2.8 7.8 7.8 0.21 11.5 0.9 2.7 3 0 0 3 3 3 0 Transcriptional activator TraM SPC25 PF06703.11 PVD18688.1 - 1.5e-46 158.1 0.0 1.7e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MgtE PF01769.16 PVD18688.1 - 0.028 14.8 0.1 0.039 14.3 0.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter Cadherin PF00028.17 PVD18689.1 - 1.1e-22 80.2 4.9 7.1e-08 32.8 0.0 5.6 4 2 1 5 5 5 5 Cadherin domain Cadherin_3 PF16184.5 PVD18689.1 - 0.00022 21.2 0.8 0.088 12.8 0.0 3.7 3 1 1 4 4 4 1 Cadherin-like EphA2_TM PF14575.6 PVD18689.1 - 0.0074 17.1 0.0 0.026 15.4 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 PVD18689.1 - 0.029 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 PVD18689.1 - 0.033 14.1 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 PVD18689.1 - 0.042 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cadherin_C_2 PF16492.5 PVD18689.1 - 0.05 14.3 0.0 0.26 12.1 0.0 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF3377 PF11857.8 PVD18689.1 - 0.16 11.9 2.8 0.12 12.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SEA PF01390.20 PVD18691.1 - 2.2e-14 53.4 4.5 0.00011 22.2 0.0 5.1 4 2 1 5 5 5 3 SEA domain CBM_14 PF01607.24 PVD18691.1 - 0.0015 18.6 1.0 0.0029 17.7 1.0 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3530 PF12048.8 PVD18691.1 - 1.1 8.6 8.1 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) SMYLE_N PF18615.1 PVD18691.1 - 1.2 8.6 4.2 1.9 8.0 4.2 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SEA PF01390.20 PVD18692.1 - 5.3e-28 97.2 3.2 4.3e-08 33.2 0.0 5.5 5 1 0 5 5 5 5 SEA domain PIEZO PF15917.5 PVD18693.1 - 0.21 11.0 6.7 0.26 10.8 5.3 1.9 2 0 0 2 2 2 0 Piezo eIF-3c_N PF05470.12 PVD18693.1 - 1.8 6.8 12.5 2.7 6.2 12.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus POX PF07526.11 PVD18693.1 - 2.8 8.5 6.5 6.9 7.2 4.1 2.4 2 1 0 2 2 2 0 Associated with HOX Med5 PF08689.10 PVD18694.1 - 0.077 10.8 0.1 0.1 10.4 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 S_100 PF01023.19 PVD18694.1 - 0.081 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain MyTH4 PF00784.17 PVD18695.1 - 3.4e-44 149.8 0.2 2.2e-24 86.0 0.0 3.3 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.18 PVD18695.1 - 2.4e-21 76.3 0.0 1e-14 54.9 0.0 3.3 3 1 0 3 3 3 2 FERM central domain FERM_N PF09379.10 PVD18695.1 - 2.5e-06 27.3 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain TNF PF00229.18 PVD18697.1 - 0.0022 17.9 0.1 0.0077 16.2 0.1 1.7 1 1 1 2 2 2 1 TNF(Tumour Necrosis Factor) family Candida_ALS_N PF11766.8 PVD18697.1 - 0.05 12.9 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Cell-wall agglutinin N-terminal ligand-sugar binding Glyco_transf_10 PF00852.19 PVD18698.1 - 7.6e-46 156.0 2.4 1.2e-45 155.4 2.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18698.1 - 2.3e-14 53.8 0.1 5.4e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18699.1 - 2.7e-49 167.3 2.3 4.2e-49 166.6 2.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18699.1 - 8.3e-06 26.2 0.4 8.3e-06 26.2 0.4 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal HEPN PF05168.14 PVD18701.1 - 3.8e-10 39.9 0.0 1.1e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 HEPN domain HATPase_c_3 PF13589.6 PVD18701.1 - 0.0013 18.6 0.0 0.43 10.4 0.1 3.0 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PID_2 PF14719.6 PVD18702.1 - 8.4e-12 45.3 0.2 1.1e-11 44.9 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 PVD18702.1 - 1.2e-08 35.1 0.3 1.8e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) WD40 PF00400.32 PVD18703.1 - 4.7e-51 169.6 24.2 8.2e-11 42.3 0.2 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18703.1 - 3.3e-32 110.6 3.1 2.9e-09 37.1 0.1 5.7 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD18703.1 - 2.9e-11 43.6 0.5 0.00067 19.6 0.1 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 PVD18703.1 - 5.9e-10 38.7 0.1 1.9e-08 34.0 0.1 2.5 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 PVD18703.1 - 1.2e-05 24.5 4.3 0.11 11.5 0.0 3.7 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PVD18703.1 - 1.2e-05 24.8 0.0 0.084 12.2 0.0 3.2 4 0 0 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 PVD18703.1 - 0.00049 19.3 0.0 0.072 12.1 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 PVD18703.1 - 0.034 14.1 0.0 0.3 11.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 PVD18703.1 - 0.21 11.3 0.3 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TNFR_c6 PF00020.18 PVD18704.1 - 3.6e-11 43.3 17.6 3.6e-07 30.5 4.4 3.2 1 1 1 2 2 2 2 TNFR/NGFR cysteine-rich region DcpS_C PF11969.8 PVD18704.1 - 0.045 14.2 0.2 0.15 12.5 0.2 1.9 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding DUF3535 PF12054.8 PVD18704.1 - 0.081 12.2 1.5 0.16 11.2 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) EGF_3 PF12947.7 PVD18704.1 - 0.18 12.0 7.2 0.47 10.7 7.2 1.8 1 0 0 1 1 1 0 EGF domain DUF485 PF04341.12 PVD18704.1 - 4.2 7.4 11.6 2.9 7.9 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 EGF_CA PF07645.15 PVD18707.1 - 4.1e-07 30.1 12.5 4.1e-07 30.1 12.5 4.6 5 0 0 5 5 5 1 Calcium-binding EGF domain EGF_3 PF12947.7 PVD18707.1 - 9.4e-06 25.7 10.1 9.4e-06 25.7 10.1 3.5 4 0 0 4 4 4 1 EGF domain cEGF PF12662.7 PVD18707.1 - 0.0013 18.6 0.7 0.0013 18.6 0.7 3.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like TNFR_c6 PF00020.18 PVD18707.1 - 0.0035 17.7 3.2 0.0035 17.7 3.2 5.9 4 1 2 6 6 6 3 TNFR/NGFR cysteine-rich region TauD PF02668.16 PVD18709.1 - 1.7e-33 116.6 0.0 2.3e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 PVD18709.1 - 1.1e-10 42.0 0.1 2.3e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 PVD18709.1 - 0.0077 15.4 0.1 0.023 13.8 0.0 1.8 3 0 0 3 3 3 1 CsiD Matrilin_ccoil PF10393.9 PVD18709.1 - 0.037 13.9 0.5 0.14 12.1 0.4 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Integrase_H2C2 PF17921.1 PVD18710.1 - 6e-13 48.7 0.4 1.4e-12 47.5 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD18710.1 - 0.0021 18.2 0.4 0.0076 16.4 0.4 2.0 1 0 0 1 1 1 1 H2C2 zinc finger GAS PF13851.6 PVD18710.1 - 0.0057 16.0 25.6 0.006 16.0 24.2 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 PVD18710.1 - 0.72 10.3 9.2 8.8 6.8 3.8 2.8 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 PVD18710.1 - 1.3 7.9 30.4 1.9 7.3 12.7 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.10 PVD18710.1 - 2.3 8.4 16.6 0.24 11.6 0.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 PVD18710.1 - 3.9 7.4 11.6 1.4 8.9 0.1 4.2 3 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LMBR1 PF04791.16 PVD18710.1 - 8.7 5.1 8.2 12 4.6 8.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Kinesin PF00225.23 PVD18711.1 - 6.1e-98 327.8 4.0 1.4e-97 326.6 4.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD18711.1 - 2.7e-47 160.5 0.0 7.4e-47 159.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding MM_CoA_mutase PF01642.22 PVD18711.1 - 0.0001 21.0 0.1 0.0001 21.0 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl-CoA mutase ADIP PF11559.8 PVD18711.1 - 0.011 15.8 7.4 0.011 15.8 7.4 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3348 PF11828.8 PVD18711.1 - 0.057 13.1 6.5 0.1 12.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) GAS PF13851.6 PVD18711.1 - 0.079 12.3 15.8 0.066 12.6 12.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 PVD18711.1 - 0.092 13.1 2.0 25 5.4 0.0 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 PVD18711.1 - 0.29 10.0 11.2 0.72 8.7 11.2 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Antimicrobial22 PF16047.5 PVD18711.1 - 0.34 10.8 1.8 0.67 9.9 1.8 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF4094 PF13334.6 PVD18711.1 - 0.63 10.5 9.3 0.29 11.6 4.5 3.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) DUF3450 PF11932.8 PVD18711.1 - 2 7.6 16.6 0.084 12.2 5.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) LPP PF04728.13 PVD18711.1 - 2.1 8.8 7.9 2.3 8.7 0.4 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 PVD18711.1 - 2.7 7.8 11.4 0.52 10.1 0.2 3.5 1 1 2 3 3 3 0 Septum formation initiator KLRAQ PF10205.9 PVD18711.1 - 4.1 7.7 16.0 0.047 13.9 3.9 3.1 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Csm1_N PF18504.1 PVD18711.1 - 9.7 6.6 9.7 35 4.8 3.4 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF812 PF05667.11 PVD18711.1 - 9.8 4.9 22.9 0.89 8.4 16.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Integrase_H2C2 PF17921.1 PVD18712.1 - 3.5e-12 46.2 3.4 5.2e-12 45.7 0.7 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD18712.1 - 0.00088 19.4 0.1 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger KfrA_N PF11740.8 PVD18712.1 - 0.036 14.8 0.5 0.036 14.8 0.5 2.7 2 1 2 4 4 4 0 Plasmid replication region DNA-binding N-term KLRAQ PF10205.9 PVD18712.1 - 0.084 13.1 0.5 0.084 13.1 0.5 3.0 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein DUF43 PF01861.16 PVD18712.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain DUF3450 PF11932.8 PVD18712.1 - 0.21 10.9 8.5 0.016 14.5 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 PVD18712.1 - 0.76 9.8 6.8 18 5.4 2.3 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 PVD18712.1 - 2.9 8.6 5.7 13 6.5 1.9 2.8 2 1 0 2 2 2 0 Initiation control protein YabA DUF4094 PF13334.6 PVD18712.1 - 4.5 7.8 8.6 0.19 12.2 0.5 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) ATG16 PF08614.11 PVD18712.1 - 6.7 6.9 21.1 2.6 8.2 17.1 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Integrase_H2C2 PF17921.1 PVD18713.1 - 2.8e-10 40.2 0.6 5.9e-10 39.1 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Spc7 PF08317.11 PVD18713.1 - 0.00012 21.0 27.1 0.0017 17.3 13.6 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF812 PF05667.11 PVD18713.1 - 0.0016 17.4 27.0 0.0054 15.7 10.6 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF812) FlaC_arch PF05377.11 PVD18713.1 - 0.017 15.5 6.0 0.56 10.6 1.2 3.5 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 PVD18713.1 - 0.091 12.8 30.8 0.032 14.3 8.9 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 PVD18713.1 - 0.11 12.4 0.0 0.11 12.4 0.0 4.1 3 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filament PF00038.21 PVD18713.1 - 0.15 11.6 26.9 0.46 10.0 26.9 1.7 1 1 0 1 1 1 0 Intermediate filament protein Cortex-I_coil PF09304.10 PVD18713.1 - 0.16 12.2 20.8 0.1 12.8 3.7 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil HrpB7 PF09486.10 PVD18713.1 - 0.59 10.5 22.5 1.3 9.4 13.0 3.6 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.13 PVD18713.1 - 1.1 10.0 15.3 4.3 8.1 1.4 3.2 1 1 2 3 3 3 0 Occludin homology domain UPF0242 PF06785.11 PVD18713.1 - 1.1 9.3 24.2 14 5.7 10.8 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 PVD18713.1 - 1.5 9.5 23.4 0.21 12.2 5.6 3.7 1 1 2 4 4 4 0 SlyX CENP-F_leu_zip PF10473.9 PVD18713.1 - 1.6 8.7 28.9 1e+02 2.9 14.0 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 PVD18713.1 - 2.2 8.5 25.0 2.1 8.6 10.7 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 PVD18713.1 - 2.3 8.3 9.5 2.6 8.1 1.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 PVD18713.1 - 2.9 6.9 36.9 0.25 10.4 16.6 3.2 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 PVD18713.1 - 3.6 7.8 19.5 1.1 9.4 1.5 3.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 PVD18713.1 - 5.3 7.5 17.6 0.38 11.1 1.4 4.1 2 1 1 3 3 3 0 Csm1 N-terminal domain LPP PF04728.13 PVD18713.1 - 7 7.1 9.7 8.3 6.9 0.2 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper ATG16 PF08614.11 PVD18713.1 - 8.3 6.6 40.5 22 5.2 19.8 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 PVD18713.1 - 9 6.7 21.2 7.7 6.9 1.7 4.2 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Kelch_1 PF01344.25 PVD18714.1 - 2.4e-38 129.5 2.5 7.7e-16 57.4 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD18714.1 - 2.7e-28 97.3 1.6 2.8e-09 36.9 0.0 5.9 4 1 2 6 6 6 4 Kelch motif BACK PF07707.15 PVD18714.1 - 2.8e-28 98.0 0.4 2.3e-27 95.1 0.0 2.5 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 PVD18714.1 - 4.4e-27 94.5 1.0 1.1e-26 93.2 1.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 PVD18714.1 - 1.3e-18 66.7 0.4 2.6e-05 24.1 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD18714.1 - 3.5e-17 61.6 2.5 0.0003 20.6 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PVD18714.1 - 1.4e-11 44.4 0.1 0.0038 17.5 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD18714.1 - 1.8e-11 43.7 0.5 0.027 14.5 0.0 4.7 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 PVD18714.1 - 0.013 15.6 0.6 0.048 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) WD40 PF00400.32 PVD18715.1 - 1.9e-24 85.5 7.3 8.2e-05 23.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD18715.1 - 0.00038 20.7 0.0 14 6.1 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Virul_Fac PF10139.9 PVD18715.1 - 0.053 11.7 4.5 0.11 10.7 4.5 1.4 1 0 0 1 1 1 0 Putative bacterial virulence factor ARGLU PF15346.6 PVD18715.1 - 2.3 8.1 25.2 0.49 10.3 21.4 1.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 KH_9 PF17904.1 PVD18716.1 - 1.1e-23 83.4 0.0 5.2e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 PVD18716.1 - 5.1e-22 77.5 1.1 1e-21 76.6 0.1 2.1 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 PVD18716.1 - 3.9e-16 58.6 1.0 2.5e-09 36.8 0.2 2.6 2 0 0 2 2 2 2 KH domain FXMRP1_C_core PF12235.8 PVD18716.1 - 3.3e-12 47.2 3.2 3.3e-12 47.2 3.2 3.6 1 1 1 3 3 3 2 Fragile X-related 1 protein core C terminal Agenet PF05641.12 PVD18716.1 - 4.1e-12 46.4 1.1 8.3e-06 26.2 0.2 3.0 2 0 0 2 2 2 2 Agenet domain KH_2 PF07650.17 PVD18716.1 - 0.031 14.1 2.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 KH domain KH_4 PF13083.6 PVD18716.1 - 0.077 12.9 0.7 6.6 6.7 0.1 2.9 2 1 1 3 3 3 0 KH domain DUF4205 PF13898.6 PVD18717.1 - 1.7e-98 329.7 0.0 2e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Tetraspanin PF00335.20 PVD18718.1 - 1.8e-49 168.6 6.8 2e-49 168.4 6.8 1.0 1 0 0 1 1 1 1 Tetraspanin family ANAPC_CDC26 PF10471.9 PVD18719.1 - 7e-10 39.6 0.2 8e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 TNF PF00229.18 PVD18720.1 - 3.4e-11 43.2 0.0 1.1e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family CzcE PF16986.5 PVD18720.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE TNF PF00229.18 PVD18721.1 - 4.9e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family FERM_C PF09380.10 PVD18723.1 - 2.1e-23 82.5 2.0 4.8e-23 81.4 2.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain RhoGEF PF00621.20 PVD18723.1 - 1.3e-20 74.4 2.9 1.4e-20 74.3 0.5 2.3 2 0 0 2 2 2 1 RhoGEF domain FERM_M PF00373.18 PVD18723.1 - 3.6e-17 62.9 0.1 8.1e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 FERM central domain PH PF00169.29 PVD18723.1 - 1e-13 51.7 14.4 2.1e-12 47.5 0.2 4.2 4 1 0 4 4 3 2 PH domain FA PF08736.11 PVD18723.1 - 5.5e-13 48.8 4.1 5.5e-13 48.8 4.1 2.0 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 PVD18723.1 - 2.8e-07 30.4 0.1 2.2e-06 27.5 0.1 2.5 3 0 0 3 3 3 1 FERM N-terminal domain PH_13 PF16652.5 PVD18723.1 - 0.0063 16.3 3.1 0.12 12.1 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 PVD18723.1 - 0.05 13.6 0.2 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 PH domain DUF5031 PF16434.5 PVD18723.1 - 0.065 12.4 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) PH_9 PF15410.6 PVD18723.1 - 0.24 11.8 5.4 0.32 11.4 0.7 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain DGF-1_C PF11040.8 PVD18723.1 - 9.3 6.3 7.7 44 4.2 0.7 3.3 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Peptidase_C2 PF00648.21 PVD18725.1 - 2e-114 381.6 0.1 2.9e-114 381.1 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD18725.1 - 4.4e-35 121.0 0.1 7.4e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 PVD18725.1 - 3.8e-13 49.6 0.4 8.1e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 C2 domain Nkap_C PF06047.11 PVD18726.1 - 4.7e-40 135.8 1.3 4.7e-40 135.8 1.3 1.8 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain LRR_8 PF13855.6 PVD18728.1 - 4.1e-22 77.7 7.7 2.1e-08 33.8 2.4 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD18728.1 - 4.5e-14 52.3 15.2 0.00048 20.5 2.9 4.7 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 PVD18728.1 - 9.3e-13 48.3 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 PVD18728.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 PVD18728.1 - 0.04 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain LRR_1 PF00560.33 PVD18728.1 - 0.058 14.0 22.0 14 6.7 0.0 6.9 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD18728.1 - 6 7.2 20.8 7.8 6.8 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich repeat zf-RING_2 PF13639.6 PVD18729.1 - 7.3e-09 35.8 7.8 7.3e-09 35.8 7.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PVD18729.1 - 5.6e-08 32.5 5.9 5.6e-08 32.5 5.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD18729.1 - 2.1e-07 30.8 6.4 2.1e-07 30.8 6.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD18729.1 - 5.6e-07 29.6 8.0 5.6e-07 29.6 8.0 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD18729.1 - 2.3e-06 27.3 4.5 2.3e-06 27.3 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD18729.1 - 4.6e-06 26.4 8.1 4.6e-06 26.4 8.1 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD18729.1 - 0.00061 19.6 8.1 0.00061 19.6 8.1 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD18729.1 - 0.0091 15.9 6.3 0.0091 15.9 6.3 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD18729.1 - 0.011 15.8 2.8 0.021 14.8 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 PVD18729.1 - 0.015 15.4 5.2 2.6 8.2 0.1 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 PVD18729.1 - 0.035 14.4 5.4 0.12 12.7 5.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain CbeA_antitoxin PF06154.11 PVD18729.1 - 0.063 13.9 0.1 0.099 13.2 0.1 1.3 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A zf-RING_11 PF17123.5 PVD18729.1 - 2.1 8.2 7.8 0.42 10.4 0.7 2.7 2 0 0 2 2 2 0 RING-like zinc finger Rad50_zn_hook PF04423.14 PVD18729.1 - 2.5 8.0 6.4 5.2 7.0 0.2 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PVD18729.1 - 3.1 7.7 9.7 0.13 12.0 3.2 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 PVD18729.1 - 3.7 7.8 7.6 30 4.8 7.6 2.5 1 1 0 1 1 1 0 FYVE zinc finger Arrestin_N PF00339.29 PVD18732.1 - 7.2e-39 133.2 0.0 6.6e-35 120.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD18732.1 - 7.1e-29 101.0 0.1 1.4e-28 100.0 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Gryzun PF07919.12 PVD18732.1 - 0.19 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi SAP130_C PF16014.5 PVD18733.1 - 2.4e-43 148.8 5.5 2.4e-43 148.8 5.5 6.1 1 1 2 5 5 5 2 Histone deacetylase complex subunit SAP130 C-terminus zf-C2H2_4 PF13894.6 PVD18734.1 - 8.9e-14 51.0 69.4 0.1 13.5 0.3 11.0 10 0 0 10 10 10 8 C2H2-type zinc finger zf-Di19 PF05605.12 PVD18734.1 - 7.1e-10 39.0 59.8 9.4e-06 25.8 10.9 8.6 5 2 2 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 PVD18734.1 - 0.0018 18.6 0.8 0.0018 18.6 0.8 10.0 9 2 0 9 9 9 1 Zinc-finger double domain zf-C2H2 PF00096.26 PVD18734.1 - 0.067 13.7 0.2 0.067 13.7 0.2 10.4 10 0 0 10 10 10 0 Zinc finger, C2H2 type zf-met PF12874.7 PVD18734.1 - 0.12 12.8 0.2 0.12 12.8 0.2 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD18734.1 - 0.13 12.6 53.6 0.19 12.1 1.7 8.7 2 2 5 7 7 7 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 PVD18734.1 - 0.27 11.2 0.0 0.27 11.2 0.0 5.9 5 1 1 6 6 6 0 Transposase zinc-ribbon domain Trm112p PF03966.16 PVD18734.1 - 2.6 8.7 9.2 3.4 8.3 1.0 4.7 4 2 0 4 4 4 0 Trm112p-like protein DUF1360 PF07098.11 PVD18734.1 - 5.2 7.1 6.1 51 3.9 0.0 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1360) Nkap_C PF06047.11 PVD18735.1 - 1.5e-49 166.4 1.6 1.5e-49 166.4 1.6 2.4 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain SLC12 PF03522.15 PVD18735.1 - 0.44 9.5 15.1 0.78 8.7 15.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 LRIF1 PF15741.5 PVD18735.1 - 5.4 5.4 20.8 8.7 4.7 20.8 1.3 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 AAA_16 PF13191.6 PVD18736.1 - 0.0011 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 PVD18736.1 - 0.0015 17.9 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NERD PF08378.11 PVD18736.1 - 0.034 14.6 0.0 0.084 13.4 0.0 1.6 1 0 0 1 1 1 0 Nuclease-related domain AAA_11 PF13086.6 PVD18736.1 - 0.063 13.0 1.8 0.39 10.5 1.8 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PVD18736.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nexin_C PF08628.12 PVD18736.1 - 0.084 13.5 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal AAA_30 PF13604.6 PVD18736.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD18736.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 PVD18736.1 - 0.18 12.2 0.1 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 PVD18738.1 - 8.2e-07 29.2 0.1 8.4e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PVD18738.1 - 9.3e-07 29.0 0.1 1.1e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD18738.1 - 5.2e-06 26.9 0.0 8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD18738.1 - 1.2e-05 25.8 0.0 1.4e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD18738.1 - 0.0027 18.1 0.0 0.0068 16.8 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeat CBM_14 PF01607.24 PVD18741.1 - 1.2e-11 44.6 3.7 1.1e-05 25.5 1.1 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain TPR_2 PF07719.17 PVD18742.1 - 1.5e-18 65.3 3.1 1.3e-05 24.9 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD18742.1 - 2.4e-18 65.1 3.9 4.5e-06 26.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD18742.1 - 2.4e-13 49.5 5.0 9.1e-07 28.5 0.1 4.1 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 PVD18742.1 - 1.2e-11 43.9 0.8 0.022 14.9 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD18742.1 - 8.4e-11 41.9 4.2 1.5e-09 37.9 0.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD18742.1 - 3.4e-09 36.7 8.3 0.0088 16.8 0.3 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD18742.1 - 8.5e-09 35.6 6.1 2e-07 31.2 0.9 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD18742.1 - 3e-08 34.2 3.3 7.5e-05 23.3 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD18742.1 - 8.5e-08 32.1 3.0 0.014 15.7 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 PVD18742.1 - 4.9e-06 26.0 3.9 0.13 11.4 0.1 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD18742.1 - 7.6e-06 26.3 11.8 0.091 13.3 0.3 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat S1 PF00575.23 PVD18742.1 - 0.00012 22.3 0.3 0.048 14.0 0.0 2.9 2 0 0 2 2 2 1 S1 RNA binding domain TPR_20 PF14561.6 PVD18742.1 - 0.037 14.3 0.4 0.037 14.3 0.4 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD18742.1 - 0.06 13.6 0.5 0.2 11.9 0.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PVD18742.1 - 0.16 12.7 3.4 40 5.2 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TRAP_alpha PF03896.16 PVD18742.1 - 0.19 10.9 0.0 0.19 10.9 0.0 2.3 2 1 1 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit TPR_7 PF13176.6 PVD18742.1 - 0.76 10.0 6.2 31 4.9 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD18742.1 - 8.7 6.4 7.2 4.1 7.4 0.2 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TIMELESS PF04821.14 PVD18743.1 - 7.9e-22 77.8 0.6 1.9e-21 76.6 0.6 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 PVD18743.1 - 5.5e-06 25.8 0.4 8.8e-05 21.8 0.3 4.6 3 1 1 4 4 4 2 Timeless protein C terminal region XAF1_C PF18608.1 PVD18743.1 - 0.022 14.3 0.1 0.065 12.8 0.1 1.8 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain SesA PF17107.5 PVD18743.1 - 0.17 12.1 1.8 7.3 6.8 0.1 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Gtr1_RagA PF04670.12 PVD18744.1 - 1.8e-106 354.7 0.3 2.3e-106 354.4 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD18744.1 - 1.7e-08 34.7 0.0 5.5e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD18744.1 - 2.3e-08 33.8 0.0 4.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 PVD18744.1 - 2e-07 30.6 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD18744.1 - 1.3e-06 28.5 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD18744.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PVD18744.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 PVD18744.1 - 0.063 13.8 0.3 0.32 11.5 0.1 2.1 2 2 0 2 2 2 0 ABC transporter DUF815 PF05673.13 PVD18744.1 - 0.085 12.0 0.5 0.56 9.3 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 PVD18744.1 - 0.1 12.5 0.8 4.1 7.3 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Cyclin_C PF02984.19 PVD18745.1 - 2.9e-28 98.3 0.0 6.6e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 PVD18745.1 - 2.7e-25 88.6 6.3 1e-15 57.6 0.1 3.3 1 1 2 3 3 3 3 Cyclin, N-terminal domain Lig_chan-Glu_bd PF10613.9 PVD18748.1 - 3e-25 88.6 0.0 5.2e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD18748.1 - 5.6e-24 84.7 0.0 1.2e-23 83.6 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD18748.1 - 7.7e-19 68.0 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 PVD18748.1 - 0.54 10.3 16.6 0.08 12.9 9.4 2.4 2 0 0 2 2 2 0 Ion channel Glyco_transf_10 PF00852.19 PVD18749.1 - 1.4e-45 155.1 1.8 2.3e-45 154.5 1.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18749.1 - 4.7e-13 49.6 0.0 9.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18750.1 - 3.1e-49 167.1 1.9 4.8e-49 166.5 1.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18750.1 - 6.1e-15 55.6 1.2 1.1e-14 54.8 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18751.1 - 1.5e-56 190.9 5.4 8.1e-28 97.3 0.1 3.3 2 1 1 3 3 3 3 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18751.1 - 1.1e-13 51.6 0.1 2.7e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF1661 PF07877.11 PVD18751.1 - 0.017 14.8 1.1 7.9 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Glyco_transf_10 PF00852.19 PVD18752.1 - 8.6e-47 159.1 1.1 1.4e-46 158.5 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18752.1 - 8.2e-14 52.0 0.0 1.8e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18753.1 - 4.9e-47 159.9 1.3 8.9e-47 159.1 1.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18753.1 - 1.9e-15 57.2 0.3 4.6e-15 56.0 0.3 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18754.1 - 2e-46 158.0 1.4 2.9e-46 157.4 1.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18754.1 - 5.1e-06 26.9 2.2 0.00014 22.2 0.8 2.6 1 1 1 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18755.1 - 4e-47 160.2 1.2 6.5e-47 159.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18755.1 - 9.1e-10 39.0 0.0 0.0024 18.3 0.0 2.7 2 0 0 2 2 2 2 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD18756.1 - 3.5e-46 157.1 3.1 5.7e-46 156.5 3.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18756.1 - 9.3e-16 58.3 0.7 1.6e-15 57.5 0.1 1.7 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF3302 PF11742.8 PVD18756.1 - 0.036 14.2 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Glyco_transf_10 PF00852.19 PVD18757.1 - 3.2e-45 154.0 1.5 3.2e-45 154.0 1.5 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18757.1 - 1.7e-15 57.4 0.5 4.5e-15 56.1 0.5 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Carot_N PF09150.10 PVD18757.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Glyco_transf_10 PF00852.19 PVD18758.1 - 3.4e-44 150.7 1.7 4.7e-44 150.2 1.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_transf_10 PF00852.19 PVD18759.1 - 7.4e-36 123.5 3.2 2.6e-35 121.7 3.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD18759.1 - 1.7e-15 57.4 0.6 4.1e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal zf-C2HE PF16278.5 PVD18760.1 - 1.9e-14 53.9 0.7 4.1e-14 52.8 0.7 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 PVD18760.1 - 1.8e-12 47.7 2.3 1.9e-12 47.7 0.6 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 PVD18760.1 - 0.00026 21.7 0.7 0.00076 20.2 0.1 2.0 2 1 0 2 2 2 1 HIT domain zf-C2H2 PF00096.26 PVD18760.1 - 0.002 18.5 0.7 0.002 18.5 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD18760.1 - 0.01 16.6 0.6 0.01 16.6 0.6 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PVD18760.1 - 0.017 15.5 1.9 0.032 14.6 1.9 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 PVD18760.1 - 0.025 14.6 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 PVD18760.1 - 0.062 13.7 0.1 0.062 13.7 0.1 2.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FCS PF06467.14 PVD18760.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif His_Me_b4a2 PF18275.1 PVD18760.1 - 0.074 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain RCC1 PF00415.18 PVD18761.1 - 2.2e-61 204.3 26.4 1.6e-14 54.2 2.0 5.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD18761.1 - 3.8e-40 134.9 31.7 1.9e-13 49.8 1.4 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 PVD18761.1 - 2.8e-20 72.6 0.3 4.8e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_C25_C PF03785.14 PVD18761.1 - 0.016 15.1 0.8 2.5 8.0 0.0 3.3 4 0 0 4 4 4 0 Peptidase family C25, C terminal ig-like domain Hira PF07569.11 PVD18761.1 - 0.028 14.1 0.9 36 4.0 0.0 3.8 3 2 1 4 4 4 0 TUP1-like enhancer of split BACK PF07707.15 PVD18761.1 - 0.069 13.3 0.1 11 6.2 0.0 3.1 4 0 0 4 4 4 0 BTB And C-terminal Kelch SUKH-3 PF14433.6 PVD18761.1 - 0.48 10.9 4.3 47 4.4 0.1 4.1 4 1 1 5 5 5 0 SUKH-3 immunity protein COesterase PF00135.28 PVD18762.1 - 6.8e-154 513.5 0.0 8.3e-154 513.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD18762.1 - 2.8e-09 37.2 0.1 5.2e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF885 PF05960.11 PVD18763.1 - 8e-135 451.5 0.0 9.2e-135 451.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) AKAP7_NLS PF10469.9 PVD18764.1 - 6.3e-48 163.4 0.0 8.8e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 PVD18764.1 - 1.1e-10 41.2 1.0 4.5e-10 39.2 0.5 2.2 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 PVD18764.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 KH domain KH_4 PF13083.6 PVD18764.1 - 0.13 12.1 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 KH domain UCH PF00443.29 PVD18765.1 - 1.2e-56 192.1 0.2 5.3e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD18765.1 - 1.5e-06 28.0 0.6 1.5e-06 28.0 0.6 3.9 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 PVD18765.1 - 0.00029 21.1 10.3 0.00029 21.1 10.3 3.5 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD18765.1 - 0.035 14.1 3.4 0.067 13.2 1.2 2.7 1 1 1 2 2 2 0 RING-type zinc-finger DUF4746 PF15928.5 PVD18765.1 - 0.095 12.1 7.4 0.18 11.2 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FANCI_S1-cap PF14674.6 PVD18765.1 - 0.34 11.0 2.0 4.7 7.4 0.2 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap RPN2_C PF18004.1 PVD18765.1 - 0.76 9.7 6.5 1.9 8.4 6.5 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4611 PF15387.6 PVD18765.1 - 1.1 9.6 8.6 4.9 7.4 8.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ribosomal_60s PF00428.19 PVD18765.1 - 1.5 9.5 16.0 5.5 7.7 16.0 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-RING_11 PF17123.5 PVD18765.1 - 3.1 7.6 13.3 0.85 9.4 6.4 3.3 3 0 0 3 3 3 0 RING-like zinc finger Gar1 PF04410.14 PVD18766.1 - 2.1e-43 147.8 0.1 2.1e-43 147.8 0.1 2.1 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region AAR2 PF05282.11 PVD18766.1 - 0.39 10.1 4.4 2.1 7.7 2.5 2.0 2 0 0 2 2 2 0 AAR2 protein HAD_2 PF13419.6 PVD18767.1 - 4.5e-23 82.3 0.0 5.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD18767.1 - 7.2e-18 65.6 0.0 4e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD18767.1 - 0.00013 22.4 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PVD18767.1 - 0.0026 17.8 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD18767.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NiFe_hyd_3_EhaA PF17367.2 PVD18767.1 - 0.029 14.5 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF4834 PF16118.5 PVD18768.1 - 0.052 14.5 1.5 1.3 10.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) KOG2701 PF09762.9 PVD18768.1 - 0.082 13.1 0.1 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) DUF4038 PF13204.6 PVD18768.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) SpoIIIAH PF12685.7 PVD18769.1 - 0.014 15.3 0.3 0.047 13.5 0.0 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Ctr PF04145.15 PVD18769.1 - 0.17 12.5 0.0 0.59 10.7 0.0 1.9 1 0 0 1 1 1 0 Ctr copper transporter family DUF3306 PF11748.8 PVD18769.1 - 1.6 9.6 11.8 0.86 10.5 8.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Phage_Gp23 PF10669.9 PVD18769.1 - 2.1 8.7 3.6 0.84 10.0 0.4 2.0 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) PLA2_B PF01735.18 PVD18770.1 - 1.9e-76 257.5 0.0 8.6e-54 182.7 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.30 PVD18770.1 - 2.7e-14 53.3 0.1 5.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 C2 domain 7tm_1 PF00001.21 PVD18773.1 - 1.1e-08 34.8 6.5 1.7e-08 34.2 6.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD18774.1 - 5.2e-07 29.3 1.2 7.5e-07 28.7 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 PVD18774.1 - 0.0093 15.1 5.1 0.064 12.4 0.6 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) SHR3_chaperone PF08229.11 PVD18774.1 - 0.23 10.4 2.8 0.37 9.7 0.5 2.2 1 1 1 2 2 2 0 ER membrane protein SH3 DUF3671 PF12420.8 PVD18774.1 - 8.9 6.4 8.6 1.9 8.6 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function zf-H2C2_5 PF13909.6 PVD18776.1 - 1e-06 28.4 2.0 2.9e-06 26.9 2.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD18776.1 - 0.0061 17.0 2.8 0.0061 17.0 2.8 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 PVD18776.1 - 0.02 15.2 1.0 0.042 14.1 1.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 PVD18776.1 - 0.039 14.8 1.8 0.039 14.8 1.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger OrsD PF12013.8 PVD18776.1 - 0.12 12.8 4.1 0.16 12.4 0.2 2.7 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 PVD18776.1 - 1.1 9.4 5.7 0.38 10.8 0.8 2.3 2 0 0 2 2 2 0 BED zinc finger COX16 PF14138.6 PVD18778.1 - 0.0016 18.9 1.6 4.1 8.0 0.0 3.4 2 1 1 3 3 3 2 Cytochrome c oxidase assembly protein COX16 COX14 PF14880.6 PVD18778.1 - 0.13 12.2 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly THOC2_N PF16134.5 PVD18781.1 - 0.0076 14.9 8.4 0.0087 14.7 8.4 1.0 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus DDHD PF02862.17 PVD18781.1 - 0.93 9.6 5.5 1.1 9.4 5.5 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 PVD18781.1 - 3.1 7.5 18.6 3.3 7.5 18.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 PVD18781.1 - 6.9 5.5 9.2 8.1 5.3 9.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 PVD18781.1 - 7.9 4.5 25.3 7.9 4.5 25.3 1.0 1 0 0 1 1 1 0 Nop14-like family CUB PF00431.20 PVD18782.1 - 0.00035 20.9 0.3 0.00094 19.5 0.0 1.9 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 PVD18782.1 - 0.013 15.7 1.7 0.035 14.3 1.7 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.24 PVD18783.1 - 6.6e-55 185.3 0.0 1.4e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 PVD18783.1 - 1.9e-29 101.3 13.2 4e-12 45.9 1.6 4.5 4 0 0 4 4 4 3 Hemopexin Ldl_recept_a PF00057.18 PVD18783.1 - 1.1e-13 51.1 24.5 2.3e-06 27.7 1.5 4.8 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A PG_binding_1 PF01471.18 PVD18783.1 - 6.7e-07 29.4 0.1 2.3e-06 27.7 0.1 2.0 1 0 0 1 1 1 1 Putative peptidoglycan binding domain CUB PF00431.20 PVD18783.1 - 4.7e-06 26.9 0.8 0.017 15.4 0.0 3.0 3 0 0 3 3 3 2 CUB domain Astacin PF01400.24 PVD18783.1 - 0.02 14.5 1.5 0.42 10.2 0.1 3.1 4 0 0 4 4 4 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 PVD18783.1 - 0.022 14.0 0.8 0.046 12.9 0.8 1.4 1 0 0 1 1 1 0 Met-zincin APC_r PF05923.12 PVD18783.1 - 0.025 14.3 0.1 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 APC repeat Reprolysin_4 PF13583.6 PVD18783.1 - 0.046 13.4 0.1 0.094 12.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CsoS2_M PF12288.8 PVD18783.1 - 0.053 12.9 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region Lectin_C PF00059.21 PVD18783.1 - 0.054 14.2 0.0 0.21 12.4 0.0 2.1 1 0 0 1 1 1 0 Lectin C-type domain Reprolysin_5 PF13688.6 PVD18783.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.9 2 0 0 2 2 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD18783.1 - 0.25 11.9 1.4 0.59 10.7 1.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LRRNT PF01462.18 PVD18783.1 - 5.6 6.7 14.0 0.024 14.3 1.5 3.2 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain GDPD PF03009.17 PVD18788.1 - 1.7e-19 70.6 0.0 5.1e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RNA_pol_Rpb2_3 PF04565.16 PVD18788.1 - 0.045 13.9 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 zf-C2H2 PF00096.26 PVD18789.1 - 6.2e-13 48.4 26.0 3.8e-05 23.9 0.6 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD18789.1 - 4.6e-12 45.5 24.1 6.5e-07 29.0 2.9 4.6 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD18789.1 - 6.1e-10 39.1 21.6 0.0025 18.5 2.5 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD18789.1 - 1.1e-06 28.8 19.6 0.00013 22.2 0.1 5.7 5 0 0 5 5 5 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 PVD18789.1 - 0.00048 19.7 4.0 0.013 15.1 0.1 3.0 3 0 0 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 PVD18789.1 - 0.00091 19.5 7.5 0.53 10.7 0.2 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD18789.1 - 0.0076 16.5 9.8 0.31 11.4 1.4 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 PVD18789.1 - 0.017 15.5 7.0 0.85 10.1 0.3 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 PVD18789.1 - 0.27 11.9 5.8 48 4.7 5.8 3.4 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats OrsD PF12013.8 PVD18789.1 - 1.6 9.2 13.1 0.49 10.8 0.4 3.3 2 1 2 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 PVD18789.1 - 2.8 7.0 5.2 34 3.5 5.5 2.0 1 1 0 1 1 1 0 Putative actin-like family Lamp PF01299.17 PVD18790.1 - 7e-11 42.2 10.4 8.4e-11 41.9 5.9 2.5 2 0 0 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 PVD18790.1 - 0.0014 18.4 6.5 0.0029 17.5 0.7 2.8 2 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) MYEOV2 PF15004.6 PVD18791.1 - 1.5e-22 79.8 2.2 2.7e-22 79.0 2.2 1.4 1 1 0 1 1 1 1 Myeloma-overexpressed-like Y_phosphatase PF00102.27 PVD18792.1 - 3.7e-114 380.2 0.4 4.6e-76 255.5 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 PVD18792.1 - 8.2e-10 38.6 0.0 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD18792.1 - 5.9e-07 29.7 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family F5_F8_type_C PF00754.25 PVD18792.1 - 1.5e-06 28.3 1.0 9.3e-05 22.6 0.2 2.5 2 0 0 2 2 2 1 F5/8 type C domain PTPlike_phytase PF14566.6 PVD18792.1 - 3.4e-05 24.0 0.0 0.062 13.4 0.0 2.8 2 0 0 2 2 2 2 Inositol hexakisphosphate Myotub-related PF06602.14 PVD18792.1 - 0.00021 20.4 0.0 0.85 8.5 0.0 3.0 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain Laminin_EGF PF00053.24 PVD18792.1 - 0.017 15.2 66.6 0.97 9.6 9.7 5.1 3 1 2 5 5 5 0 Laminin EGF domain Syndecan PF01034.20 PVD18792.1 - 0.021 14.7 0.9 0.051 13.5 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 PVD18792.1 - 0.095 12.1 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PVD18792.1 - 0.13 13.1 0.0 0.33 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DSL PF01414.19 PVD18793.1 - 0.011 16.1 16.5 0.011 16.1 16.5 5.1 4 0 0 4 4 4 0 Delta serrate ligand Y_phosphatase PF00102.27 PVD18794.1 - 3e-201 665.2 4.1 4.4e-76 255.5 0.3 6.5 4 1 2 6 6 6 6 Protein-tyrosine phosphatase DSPc PF00782.20 PVD18794.1 - 4.7e-18 65.3 2.8 0.0051 16.6 0.0 5.1 6 0 0 6 6 6 4 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD18794.1 - 7e-13 49.1 0.1 0.028 14.4 0.0 4.5 4 0 0 4 4 4 4 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD18794.1 - 7.3e-08 32.7 0.0 0.42 10.7 0.0 4.9 4 0 0 4 4 4 3 Inositol hexakisphosphate Myotub-related PF06602.14 PVD18794.1 - 3.7e-06 26.1 1.6 1.7 7.5 0.0 5.4 6 0 0 6 6 6 3 Myotubularin-like phosphatase domain DUF4627 PF15425.6 PVD18794.1 - 3.1 7.4 4.7 2.8 7.5 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4627) Y_phosphatase PF00102.27 PVD18795.1 - 2.4e-28 99.3 4.8 8.5e-16 58.2 0.1 2.9 2 1 1 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 PVD18796.1 - 5.3e-29 101.5 0.1 7e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD18796.1 - 0.00056 19.9 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PVD18796.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Phage_holin_3_6 PF07332.11 PVD18797.1 - 0.13 12.4 0.6 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_2_4 PF16082.5 PVD18798.1 - 0.05 13.3 5.3 3.1 7.6 0.5 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PMP22_Claudin PF00822.20 PVD18798.1 - 0.18 11.7 5.2 0.25 11.2 5.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD18798.1 - 4.5 7.0 9.4 28 4.4 9.4 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Serpin PF00079.20 PVD18799.1 - 3.8e-90 302.9 3.5 2.9e-66 224.3 1.6 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) Flavoprotein PF02441.19 PVD18799.1 - 0.033 13.9 0.0 0.069 12.9 0.0 1.7 1 1 0 1 1 1 0 Flavoprotein Claudin_2 PF13903.6 PVD18800.1 - 1.2e-06 28.5 4.8 3.6e-06 26.9 3.2 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD18800.1 - 0.0056 16.9 0.6 0.0056 16.9 0.6 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 PVD18800.1 - 0.024 14.5 6.6 0.028 14.3 0.1 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin family GP41 PF00517.17 PVD18800.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein FTR1 PF03239.14 PVD18800.1 - 0.34 10.0 3.5 0.47 9.6 2.0 1.8 2 0 0 2 2 2 0 Iron permease FTR1 family Phage_holin_3_6 PF07332.11 PVD18800.1 - 1.1 9.3 10.6 0.28 11.3 1.9 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III OppC_N PF12911.7 PVD18800.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.9 3 1 1 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Clc-like PF07062.12 PVD18800.1 - 2 7.8 8.1 1.5 8.2 4.2 2.5 1 1 1 2 2 2 0 Clc-like Serpin PF00079.20 PVD18801.1 - 4.2e-110 368.6 1.6 5.3e-110 368.2 1.6 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Flavoprotein PF02441.19 PVD18801.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Flavoprotein HECT PF00632.25 PVD18802.1 - 4.4e-84 282.6 0.1 1.2e-83 281.2 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 PVD18802.1 - 8.4e-21 74.3 0.3 1.9e-20 73.2 0.3 1.7 1 0 0 1 1 1 1 WWE domain Arm PF00514.23 PVD18802.1 - 0.027 14.5 3.7 0.27 11.3 0.0 4.0 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 PVD18802.1 - 7 6.3 7.1 3.3 7.4 0.1 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis SUIM_assoc PF16619.5 PVD18803.1 - 0.085 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FAM124 PF15067.6 PVD18806.1 - 2.1e-66 223.9 0.0 8e-66 222.0 0.0 1.8 1 1 0 1 1 1 1 FAM124 family CCDC106 PF15794.5 PVD18806.1 - 0.34 10.6 0.8 0.59 9.8 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CARD PF00619.21 PVD18807.1 - 3.5e-06 27.0 1.5 2.6e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 Caspase recruitment domain Neuralized PF07177.12 PVD18807.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Neuralized T4_baseplate PF12322.8 PVD18807.1 - 0.045 13.2 0.0 0.19 11.2 0.0 1.9 1 1 0 2 2 2 0 T4 bacteriophage base plate protein BEX PF04538.12 PVD18807.1 - 0.12 13.0 3.4 0.25 11.9 3.4 1.5 1 0 0 1 1 1 0 Brain expressed X-linked like family FGGY_C PF02782.16 PVD18809.1 - 1.5e-40 139.1 0.6 2.3e-40 138.5 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 PVD18809.1 - 3.2e-34 118.6 0.2 6.5e-33 114.3 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain TLD PF07534.16 PVD18810.1 - 1.1e-27 97.0 0.3 2.4e-27 95.9 0.1 1.7 2 0 0 2 2 2 1 TLD RabGAP-TBC PF00566.18 PVD18810.1 - 1e-14 54.7 0.3 2e-14 53.8 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SPG48 PF14764.6 PVD18810.1 - 0.017 15.6 0.1 0.052 14.0 0.0 1.8 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking RBP_receptor PF14752.6 PVD18811.1 - 2.3e-75 254.4 13.0 2e-53 181.9 10.2 2.0 1 1 0 2 2 2 2 Retinol binding protein receptor Arm PF00514.23 PVD18811.1 - 0.23 11.6 0.4 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Na_K-ATPase PF00287.18 PVD18811.1 - 4.2 6.5 4.9 8.1 5.5 4.9 1.4 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain RBP_receptor PF14752.6 PVD18812.1 - 1.5e-78 264.9 22.5 1.9e-78 264.6 22.5 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor Sid-5 PF17204.3 PVD18812.1 - 0.004 17.3 0.0 0.004 17.3 0.0 3.0 2 1 1 3 3 3 1 Sid-5 family CBM_14 PF01607.24 PVD18813.1 - 1.4e-07 31.5 4.2 2.9e-07 30.5 4.2 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CH PF00307.31 PVD18814.1 - 4.5e-48 162.0 0.4 3e-13 49.9 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain Filamin PF00630.19 PVD18814.1 - 2.7e-45 153.4 3.1 1.7e-12 48.1 0.0 7.4 6 1 1 7 7 7 7 Filamin/ABP280 repeat CAMSAP_CH PF11971.8 PVD18814.1 - 3.2e-09 36.5 0.0 0.0051 16.6 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain Invasin_D3 PF09134.10 PVD18814.1 - 0.017 15.4 0.7 3.4 8.0 0.2 3.5 3 0 0 3 3 3 0 Invasin, domain 3 RTX PF02382.15 PVD18814.1 - 2.6 7.6 5.1 4.4 6.9 5.1 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Filamin PF00630.19 PVD18815.1 - 3.6e-08 34.1 0.0 5.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat MCM PF00493.23 PVD18818.1 - 1.8e-101 337.9 0.0 3e-101 337.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PVD18818.1 - 3.3e-35 120.7 1.7 6.5e-35 119.7 1.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 PVD18818.1 - 3.2e-24 85.5 1.0 1.1e-23 83.8 1.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 PVD18818.1 - 1.4e-22 79.9 1.9 3.4e-22 78.7 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PVD18818.1 - 1.8e-07 30.7 0.0 7.5e-06 25.5 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PVD18818.1 - 2.7e-06 27.4 0.0 6.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 PVD18818.1 - 0.00063 19.5 0.4 0.0034 17.2 0.1 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 PVD18818.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM_bind PF09739.9 PVD18818.1 - 0.021 13.3 0.2 0.033 12.6 0.2 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ephrin_rec_like PF07699.13 PVD18818.1 - 0.29 10.9 1.6 0.63 9.9 1.6 1.5 1 0 0 1 1 1 0 Putative ephrin-receptor like Cullin_binding PF03556.15 PVD18819.1 - 1.9e-38 131.6 1.5 5.5e-38 130.1 0.3 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 PVD18819.1 - 1.7e-11 43.7 0.2 4.7e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain wnt PF00110.19 PVD18820.1 - 5.3e-41 141.2 13.0 3.8e-30 105.5 10.1 2.1 2 0 0 2 2 2 2 wnt family wnt PF00110.19 PVD18821.1 - 3.2e-11 43.4 2.0 6.1e-11 42.5 2.0 1.5 1 1 0 1 1 1 1 wnt family DUF5472 PF17566.2 PVD18821.1 - 0.068 13.1 0.6 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5472) AAA_lid_8 PF17868.1 PVD18821.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain S36_mt PF10937.8 PVD18823.1 - 0.12 13.9 0.1 0.27 12.8 0.1 1.6 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial V-set PF07686.17 PVD18824.1 - 0.00035 20.7 0.4 0.0022 18.1 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD18824.1 - 0.018 15.3 0.6 0.93 9.9 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin domain Ig_3 PF13927.6 PVD18824.1 - 0.054 14.1 1.7 0.11 13.1 0.1 2.5 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 PVD18824.1 - 0.077 13.1 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ldl_recept_b PF00058.17 PVD18826.1 - 3e-17 62.8 10.4 8.5e-07 29.4 0.0 5.8 5 1 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD18826.1 - 0.00024 21.3 7.6 0.00046 20.4 7.6 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 PVD18826.1 - 0.00048 19.8 0.0 1.2 8.7 0.0 3.9 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 PVD18827.1 - 1.6e-17 63.5 22.1 8.3e-11 42.0 7.1 5.7 5 1 0 5 5 5 2 Coagulation Factor Xa inhibitory site Sushi PF00084.20 PVD18827.1 - 4.9e-09 36.6 27.2 0.00054 20.5 4.5 4.2 2 1 2 4 4 4 3 Sushi repeat (SCR repeat) cEGF PF12662.7 PVD18827.1 - 0.0047 16.8 0.9 0.0047 16.8 0.9 6.4 5 0 0 5 5 5 2 Complement Clr-like EGF-like RRM_DME PF15628.6 PVD18827.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 RRM in Demeter RANK_CRD_2 PF18278.1 PVD18827.1 - 0.35 11.1 4.5 6 7.1 0.3 3.2 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 BRCA2 PF00634.18 PVD18827.1 - 0.51 10.1 2.0 23 4.8 0.1 2.4 2 0 0 2 2 2 0 BRCA2 repeat Pox_EPC_I2-L1 PF12575.8 PVD18828.1 - 0.042 14.1 0.6 0.91 9.8 0.0 2.5 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 SPRY PF00622.28 PVD18829.1 - 2.8e-19 69.4 0.3 1.6e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 SPRY domain SRP-alpha_N PF04086.13 PVD18829.1 - 2.3 8.1 20.3 3.9 7.3 20.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_LBD PF02931.23 PVD18830.1 - 1.3e-50 171.8 2.6 1.8e-50 171.4 2.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD18830.1 - 2.7e-15 57.1 0.6 6.9e-09 36.1 0.9 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region E6 PF00518.17 PVD18832.1 - 0.1 13.0 0.1 5.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Early Protein (E6) SEA PF01390.20 PVD18833.1 - 4.3e-08 33.2 0.0 4.3e-08 33.2 0.0 2.6 2 1 0 2 2 2 1 SEA domain DUF1218 PF06749.12 PVD18833.1 - 0.033 14.7 1.5 0.099 13.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Sigma_reg_N PF13800.6 PVD18833.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.1 2 1 0 2 2 2 0 Sigma factor regulator N-terminal Biotin_lipoyl_2 PF13533.6 PVD18836.1 - 0.22 11.4 6.5 41 4.1 0.1 5.2 4 0 0 4 4 4 0 Biotin-lipoyl like YdfZ PF14001.6 PVD18838.1 - 0.056 13.9 4.2 35 4.9 0.1 4.5 2 1 3 5 5 5 0 YdfZ protein Ig_3 PF13927.6 PVD18844.1 - 5.4e-08 33.3 0.3 0.0062 17.1 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD18844.1 - 4.2e-05 23.7 0.4 0.04 14.1 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD18844.1 - 4.8e-05 23.4 0.0 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 PVD18844.1 - 0.006 16.7 0.6 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain Hydrolase_4 PF12146.8 PVD18844.1 - 0.077 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PRIMA1 PF16101.5 PVD18844.1 - 0.12 12.4 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Adeno_E3_CR1 PF02440.15 PVD18844.1 - 0.15 11.9 1.1 7.7 6.4 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 VWD PF00094.25 PVD18846.1 - 4e-06 27.2 0.0 8.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18846.1 - 0.026 14.9 9.2 0.026 14.9 9.2 3.6 4 0 0 4 4 4 0 EGF-like domain VWD PF00094.25 PVD18847.1 - 6.4e-06 26.5 0.3 1e-05 25.8 0.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18848.1 - 0.0018 18.6 11.5 0.0054 17.1 11.5 1.9 1 0 0 1 1 1 1 EGF-like domain Prenyltransf PF01255.19 PVD18848.1 - 0.0078 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase EGF_Tenascin PF18720.1 PVD18848.1 - 1.1 9.4 9.7 3.5 7.8 8.4 2.4 2 0 0 2 2 2 0 Tenascin EGF domain Laminin_EGF PF00053.24 PVD18848.1 - 1.5 9.0 12.5 0.19 11.9 7.4 2.1 2 0 0 2 2 2 0 Laminin EGF domain VWD PF00094.25 PVD18850.1 - 0.0022 18.3 0.1 0.0054 17.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18850.1 - 0.0026 18.1 31.2 0.0074 16.6 11.7 3.9 4 0 0 4 4 4 2 EGF-like domain EGF_Tenascin PF18720.1 PVD18850.1 - 0.28 11.3 24.2 2 8.5 6.9 3.5 3 0 0 3 3 3 0 Tenascin EGF domain Laminin_EGF PF00053.24 PVD18850.1 - 4.8 7.4 34.4 0.78 9.9 7.6 4.4 4 0 0 4 4 4 0 Laminin EGF domain EGF_2 PF07974.13 PVD18851.1 - 0.02 15.3 3.3 0.052 13.9 3.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 PVD18851.1 - 0.023 14.8 0.4 0.061 13.4 0.4 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Laminin_EGF PF00053.24 PVD18851.1 - 0.46 10.7 4.0 0.2 11.8 1.0 1.9 2 0 0 2 2 2 0 Laminin EGF domain VWD PF00094.25 PVD18852.1 - 2e-29 102.9 2.1 5.3e-10 39.8 0.1 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain EGF_2 PF07974.13 PVD18852.1 - 5.8e-06 26.6 31.8 0.00019 21.7 13.0 5.6 6 0 0 6 6 6 2 EGF-like domain EGF_Tenascin PF18720.1 PVD18852.1 - 0.0003 20.8 35.0 0.001 19.0 5.9 4.8 3 0 0 3 3 3 2 Tenascin EGF domain DUF5001 PF16392.5 PVD18852.1 - 0.088 12.7 0.0 3.1 7.8 0.0 2.8 2 0 0 2 2 2 0 Ig-like domain SH3_10 PF17902.1 PVD18853.1 - 4.9e-19 68.2 0.0 1.2e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Plectin PF00681.20 PVD18853.1 - 1.1e-14 53.9 0.2 0.028 14.3 0.0 5.9 5 1 1 6 6 6 4 Plectin repeat Methyltrn_RNA_4 PF09936.9 PVD18853.1 - 0.0013 18.6 0.2 0.0045 16.9 0.2 2.0 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase SH3_1 PF00018.28 PVD18853.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain YkuI_C PF10388.9 PVD18853.1 - 0.051 13.4 1.8 0.14 11.9 1.1 2.1 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain Ldl_recept_b PF00058.17 PVD18854.1 - 2.6e-46 155.8 21.8 1.4e-10 41.5 0.1 11.0 12 0 0 12 12 12 7 Low-density lipoprotein receptor repeat class B SGL PF08450.12 PVD18854.1 - 6.9e-10 38.9 6.7 0.00022 20.9 0.1 5.2 3 3 2 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 PVD18854.1 - 3e-09 37.0 43.7 0.0012 19.1 12.0 3.6 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 PVD18854.1 - 9.2e-09 34.9 0.0 0.0002 20.7 0.0 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF5050) Arylesterase PF01731.20 PVD18854.1 - 0.00034 20.8 0.0 0.073 13.3 0.0 4.5 5 0 0 5 5 5 1 Arylesterase Lactonase PF10282.9 PVD18854.1 - 0.02 14.2 0.0 1.7 7.8 0.0 3.4 2 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller cEGF PF12662.7 PVD18854.1 - 0.022 14.7 12.7 0.89 9.5 5.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.27 PVD18854.1 - 6.5 7.2 32.7 0.031 14.6 2.9 3.7 3 0 0 3 3 3 0 EGF-like domain Nucleotid_trans PF03407.16 PVD18856.1 - 2.6e-21 76.6 0.0 3.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase MetW PF07021.12 PVD18856.1 - 0.0078 15.8 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW AMP-binding PF00501.28 PVD18858.1 - 1.3e-116 389.7 0.0 7.3e-59 199.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18858.1 - 6.2e-16 59.1 0.0 7.5e-07 30.1 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 PVD18858.1 - 4.8e-05 22.4 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Cyclophil_like2 PF18050.1 PVD18858.1 - 0.045 13.7 0.0 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Cyclophilin-like family DUF2093 PF09866.9 PVD18858.1 - 0.052 13.0 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) AMP-binding PF00501.28 PVD18859.1 - 1.8e-46 158.6 0.0 1.1e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18859.1 - 4.7e-06 27.5 0.0 1.2e-05 26.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18860.1 - 1.9e-24 86.1 0.0 2.4e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18860.1 - 2.5e-08 34.8 0.1 4.6e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18861.1 - 9.8e-19 67.2 0.0 1.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 PVD18862.1 - 3.7e-41 141.1 0.0 8.2e-29 100.4 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18862.1 - 3.6e-08 34.3 0.7 1.2e-07 32.6 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18863.1 - 1.5e-56 191.8 0.0 1.8e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18863.1 - 8.7e-08 33.0 0.4 3.2e-07 31.2 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 PVD18863.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter HSP33 PF01430.19 PVD18863.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Hsp33 protein AMP-binding PF00501.28 PVD18864.1 - 1.4e-26 93.1 0.0 6.3e-21 74.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18864.1 - 5.3e-06 27.3 0.1 2.7e-05 25.1 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18865.1 - 1.3e-56 192.0 0.1 1.5e-56 191.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18865.1 - 6.3e-09 36.7 0.1 2.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 PVD18865.1 - 0.2 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter AMP-binding PF00501.28 PVD18866.1 - 4.4e-16 58.5 0.0 5.8e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18866.1 - 3.7e-09 37.4 0.1 6.2e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18867.1 - 3.5e-22 78.6 0.1 3.9e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 PVD18867.1 - 0.0014 17.6 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter adh_short_C2 PF13561.6 PVD18867.1 - 0.038 13.5 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 PVD18868.1 - 5.2e-23 81.3 0.4 7.2e-22 77.6 0.0 1.9 1 1 1 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 PVD18868.1 - 0.005 15.7 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter AMP-binding PF00501.28 PVD18869.1 - 5.7e-52 176.7 0.0 6.7e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD18869.1 - 2.6e-08 34.7 0.2 2.4e-07 31.6 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD18870.1 - 1.3e-44 152.5 0.0 1.1e-30 106.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 PVD18870.1 - 0.0036 16.2 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter NERD PF08378.11 PVD18870.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Nuclease-related domain Peroxin-22 PF12827.7 PVD18870.1 - 0.2 11.6 0.4 9.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family Nucleotid_trans PF03407.16 PVD18872.1 - 2.8e-12 47.1 0.0 6.4e-10 39.4 0.0 2.1 1 1 1 2 2 2 2 Nucleotide-diphospho-sugar transferase AdoMetDC_leader PF08132.11 PVD18872.1 - 0.2 11.6 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide CBM_14 PF01607.24 PVD18873.1 - 4e-40 135.8 93.7 2.1e-05 24.6 5.0 12.9 12 1 0 12 12 12 11 Chitin binding Peritrophin-A domain NAD_binding_10 PF13460.6 PVD18874.1 - 3.3e-16 59.7 0.5 3.7e-16 59.5 0.5 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PVD18874.1 - 9.9e-09 35.1 0.2 1.1e-08 34.9 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PVD18874.1 - 1.7e-06 27.7 0.1 1.8e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 PVD18874.1 - 0.00022 20.7 0.1 0.00025 20.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 PVD18874.1 - 0.0017 18.6 0.1 0.0018 18.5 0.1 1.1 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 PVD18874.1 - 0.0018 18.8 0.0 0.0019 18.7 0.0 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 PVD18874.1 - 0.0025 16.9 0.1 0.0028 16.7 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 PVD18874.1 - 0.0032 17.7 0.2 0.0038 17.5 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 PVD18874.1 - 0.0034 17.5 0.2 0.0039 17.3 0.2 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 PVD18874.1 - 0.0061 15.7 0.1 0.0066 15.6 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain AlaDh_PNT_C PF01262.21 PVD18874.1 - 0.015 14.6 0.3 0.015 14.6 0.3 1.0 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 PVD18874.1 - 0.044 13.2 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PVD18874.1 - 0.052 14.0 0.5 0.073 13.5 0.5 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 PVD18874.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 PVD18875.1 - 1.3e-34 119.7 0.0 3.7e-24 85.6 0.1 2.0 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 PVD18875.1 - 1.1e-12 48.0 0.0 1.8e-12 47.3 0.1 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 PVD18875.1 - 2.8e-10 40.1 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PVD18875.1 - 4.3e-05 23.8 0.1 9.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 PVD18875.1 - 0.00015 22.0 0.1 0.00025 21.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 PVD18875.1 - 0.00021 21.7 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 PVD18875.1 - 0.0014 17.8 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PVD18875.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PVD18875.1 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 PVD18875.1 - 0.0052 16.9 0.1 0.0068 16.5 0.1 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 PVD18875.1 - 0.012 15.1 0.2 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.15 PVD18875.1 - 0.038 14.2 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.12 PVD18875.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 PVD18875.1 - 0.1 12.5 0.1 2.1 8.2 0.1 2.1 2 0 0 2 2 2 0 KR domain ApbA PF02558.16 PVD18875.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 PVD18876.1 - 1.9e-36 125.8 26.7 2.9e-26 92.2 11.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 PVD18876.1 - 0.0041 16.9 2.6 0.0041 16.9 2.6 3.0 2 1 1 3 3 3 1 Probable cobalt transporter subunit (CbtA) Sugar_tr PF00083.24 PVD18876.1 - 0.034 13.0 26.7 0.025 13.4 3.5 3.4 2 1 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 PVD18877.1 - 2.6e-10 39.8 22.9 2.5e-08 33.3 9.3 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TMEM173 PF15009.6 PVD18879.1 - 8.5e-36 123.6 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 TIR_2 PF13676.6 PVD18879.1 - 5.2e-14 52.9 0.4 1.2e-13 51.8 0.1 1.7 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 PVD18879.1 - 2.4e-08 34.0 0.1 4.7e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 TIR domain RNHCP PF12647.7 PVD18879.1 - 0.079 12.9 0.7 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 RNHCP domain RPA_interact_C PF14768.6 PVD18879.1 - 0.09 13.4 1.0 11 6.7 0.1 3.2 3 0 0 3 3 3 0 Replication protein A interacting C-terminal Rad50_zn_hook PF04423.14 PVD18879.1 - 0.13 12.1 0.2 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif PRIMA1 PF16101.5 PVD18880.1 - 0.13 12.3 0.5 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD18880.1 - 0.23 10.9 5.4 4.8 6.6 0.2 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 PVD18880.1 - 0.5 9.8 2.9 1.2 8.6 0.8 1.9 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein VIR_N PF15912.5 PVD18880.1 - 0.55 9.8 2.5 6.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal OAR PF03826.17 PVD18881.1 - 7.4e-09 35.2 4.2 7.4e-09 35.2 4.2 1.9 2 0 0 2 2 2 1 OAR domain VIR_N PF15912.5 PVD18881.1 - 0.12 11.9 0.7 0.18 11.4 0.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Chorion_2 PF03964.15 PVD18881.1 - 0.68 10.8 10.2 0.64 10.9 0.7 2.7 2 1 1 3 3 3 0 Chorion family 2 7tm_7 PF08395.12 PVD18882.1 - 6.7e-06 25.6 23.6 9.9e-05 21.7 23.6 2.0 1 1 0 1 1 1 1 7tm Chemosensory receptor 7tm_6 PF02949.20 PVD18882.1 - 5e-05 22.5 3.1 5e-05 22.5 3.1 2.0 1 1 1 2 2 2 1 7tm Odorant receptor SfLAP PF11139.8 PVD18882.1 - 0.0035 16.8 0.4 0.0035 16.8 0.4 2.4 2 1 0 2 2 2 2 Sap, sulfolipid-1-addressing protein 7tm_7 PF08395.12 PVD18883.1 - 1.2e-07 31.3 19.2 0.0006 19.1 14.9 2.1 2 0 0 2 2 2 2 7tm Chemosensory receptor PLATZ PF04640.14 PVD18883.1 - 0.027 15.1 0.2 2.2 9.0 0.3 2.7 2 0 0 2 2 2 0 PLATZ transcription factor DUF4050 PF13259.6 PVD18883.1 - 0.77 10.1 3.5 0.2 12.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) MgtE PF01769.16 PVD18883.1 - 7.5 6.9 17.3 14 6.1 1.7 3.2 3 0 0 3 3 3 0 Divalent cation transporter 7tm_6 PF02949.20 PVD18884.1 - 3.1e-05 23.2 0.1 5.6e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 7tm Odorant receptor EF-hand_7 PF13499.6 PVD18885.1 - 3.1e-11 43.6 0.6 8e-06 26.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD18885.1 - 1.4e-08 33.7 0.3 0.12 12.0 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD18885.1 - 1.3e-06 27.8 0.5 0.049 13.6 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD18885.1 - 9.3e-05 22.7 0.0 0.014 15.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PVD18885.1 - 0.0022 17.8 0.3 1 9.3 0.1 3.4 3 2 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD18885.1 - 0.0062 16.0 0.8 0.22 11.1 0.0 3.3 4 0 0 4 4 4 1 EF hand Dockerin_1 PF00404.18 PVD18885.1 - 0.0069 16.6 2.4 0.34 11.2 0.1 2.9 2 1 1 3 3 3 1 Dockerin type I domain PARG_cat PF05028.14 PVD18886.1 - 1.5e-80 271.1 0.1 1.6e-66 224.9 0.0 2.9 4 0 0 4 4 4 2 Poly (ADP-ribose) glycohydrolase (PARG) JAB PF01398.21 PVD18887.1 - 5.6e-39 132.8 0.2 1.7e-38 131.2 0.2 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 PVD18887.1 - 7.2e-29 99.8 2.4 2.3e-28 98.2 1.9 2.1 2 0 0 2 2 2 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 PVD18887.1 - 1.1e-09 38.1 0.3 2.5e-09 36.9 0.1 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PVD18887.1 - 5.2e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) AAA_16 PF13191.6 PVD18888.1 - 0.00024 21.6 0.4 0.064 13.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 PVD18888.1 - 0.0013 18.7 0.0 0.0094 15.9 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 PVD18888.1 - 0.0088 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PVD18888.1 - 0.12 11.9 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain S-methyl_trans PF02574.16 PVD18889.1 - 1.2e-37 130.2 0.0 1.9e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase ArfGap PF01412.18 PVD18889.1 - 3.5e-26 91.6 0.0 5.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 PVD18890.1 - 1.1e-43 149.6 0.0 2.1e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD18890.1 - 4e-29 101.7 0.0 6.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD18890.1 - 0.054 12.8 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like PALP PF00291.25 PVD18891.1 - 5.3e-72 242.7 0.0 3.4e-36 125.2 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Nuf2 PF03800.14 PVD18891.1 - 0.02 15.0 0.0 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Nuf2 family BsuBI_PstI_RE PF06616.11 PVD18891.1 - 0.068 12.5 0.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain DUF3039 PF11238.8 PVD18891.1 - 0.09 12.5 0.0 23 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Mucin2_WxxW PF13330.6 PVD18892.1 - 2.4e-15 57.1 7.1 5.4e-15 56.0 7.1 1.6 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region rve_3 PF13683.6 PVD18892.1 - 0.0089 15.8 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain Mtp PF03821.16 PVD18892.1 - 0.026 14.1 0.8 0.069 12.7 0.0 2.0 3 0 0 3 3 3 0 Golgi 4-transmembrane spanning transporter YajC PF02699.15 PVD18892.1 - 0.18 11.7 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Cu-oxidase_3 PF07732.15 PVD18893.1 - 5.5e-33 113.5 0.2 2.8e-30 104.8 0.4 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD18893.1 - 7.1e-33 113.3 2.2 4.8e-31 107.3 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 PVD18893.1 - 2.2e-15 57.1 0.0 7.3e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD18894.1 - 2e-33 115.0 1.2 1.7e-32 112.0 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 PVD18894.1 - 1.3e-30 105.8 1.6 1.4e-29 102.5 0.2 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 PVD18894.1 - 8.2e-23 81.3 0.0 2.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Ecm33 PF12454.8 PVD18895.1 - 0.068 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LRR_8 PF13855.6 PVD18896.1 - 5e-19 67.8 4.7 5e-10 39.0 0.5 1.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD18896.1 - 2.1e-06 28.0 0.7 0.0013 19.1 0.0 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD18896.1 - 2.9e-05 24.0 0.1 4.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD18896.1 - 0.00045 19.8 0.0 0.00057 19.4 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PVD18896.1 - 2.8 8.2 6.6 6.2 7.1 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 PVD18897.1 - 4.3e-13 48.8 1.7 6.3e-11 41.9 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD18897.1 - 0.00013 22.3 0.3 0.00056 20.3 0.0 2.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD18897.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) CD34_antigen PF06365.12 PVD18897.1 - 0.061 12.9 0.2 0.25 10.9 0.1 2.1 2 1 0 2 2 2 0 CD34/Podocalyxin family Gly_kinase PF02595.15 PVD18897.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family Glyco_transf_11 PF01531.16 PVD18898.1 - 7.2e-31 107.5 0.0 9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD18898.1 - 0.00087 19.1 1.2 0.0027 17.5 0.5 1.8 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase Pkinase_Tyr PF07714.17 PVD18899.1 - 4.5e-91 304.7 0.0 4.6e-90 301.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18899.1 - 4.3e-43 147.6 0.0 8.4e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD18899.1 - 2e-28 98.3 0.9 1.8e-14 53.6 0.2 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 PVD18899.1 - 7e-22 77.8 0.1 1.9e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD18899.1 - 2.1e-18 66.4 4.2 3.1e-10 40.4 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD18899.1 - 1.2e-12 47.6 10.6 0.00034 20.9 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 PVD18899.1 - 1.3e-12 47.7 5.1 4.6e-06 26.8 0.2 4.8 2 1 3 5 5 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD18899.1 - 3.3e-12 45.4 6.8 0.0019 18.5 0.0 6.2 6 0 0 6 6 5 2 Ankyrin repeat Haspin_kinase PF12330.8 PVD18899.1 - 0.00031 19.8 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD18899.1 - 0.00071 19.0 0.1 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD18899.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2HE PF16278.5 PVD18899.1 - 0.13 12.8 1.2 1.3 9.6 0.0 2.7 3 0 0 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger Annexin PF00191.20 PVD18900.1 - 8.2e-101 330.1 14.1 2.5e-25 88.3 0.5 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 PVD18900.1 - 0.013 15.4 0.5 6.8 6.7 0.0 3.5 3 1 0 4 4 4 0 Myb DNA-binding like OST-HTH PF12872.7 PVD18900.1 - 0.097 12.5 0.2 11 5.9 0.0 3.1 3 1 0 3 3 3 0 OST-HTH/LOTUS domain zf-C2H2 PF00096.26 PVD18901.1 - 1.1e-16 60.2 25.0 1.9e-05 24.9 0.6 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD18901.1 - 1.7e-12 47.1 23.6 0.0015 19.2 0.8 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD18901.1 - 3.1e-11 43.1 27.9 4.6e-05 23.7 0.3 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD18901.1 - 9.5e-08 32.1 4.3 0.45 10.9 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD18901.1 - 0.00044 20.2 20.0 0.58 10.2 0.5 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf_UBZ PF18439.1 PVD18901.1 - 0.00063 19.3 8.2 0.21 11.2 0.0 4.4 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 PVD18901.1 - 0.0012 19.1 13.1 0.0098 16.2 0.2 3.7 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 PVD18901.1 - 0.0037 17.4 5.2 0.068 13.3 0.2 3.2 2 2 1 3 3 3 1 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 PVD18901.1 - 0.021 14.4 12.7 0.24 11.0 0.2 3.0 3 0 0 3 3 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 PVD18901.1 - 0.035 13.9 0.5 6.5 6.7 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 PVD18901.1 - 0.038 14.0 6.1 0.54 10.3 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 PVD18901.1 - 0.13 12.0 2.8 1.2 8.9 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.9 PVD18901.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.8 4 0 0 4 4 3 0 Zinc-finger domain Lar_restr_allev PF14354.6 PVD18901.1 - 0.4 11.1 3.1 10 6.6 0.4 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar LIM PF00412.22 PVD18901.1 - 1.1 9.6 12.0 6.9 7.0 7.1 3.6 1 1 1 2 2 2 0 LIM domain HNH_5 PF14279.6 PVD18901.1 - 1.5 8.8 6.6 15 5.5 0.5 3.6 3 0 0 3 3 3 0 HNH endonuclease Zn_ribbon_recom PF13408.6 PVD18901.1 - 1.7 9.2 6.2 13 6.4 0.3 2.9 3 0 0 3 3 2 0 Recombinase zinc beta ribbon domain zf-LYAR PF08790.11 PVD18901.1 - 1.7 8.6 16.8 1.8 8.5 0.2 4.6 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 PVD18901.1 - 1.9 8.8 6.7 5.3 7.4 0.1 3.3 3 0 0 3 3 2 0 zinc-ribbon DZR PF12773.7 PVD18901.1 - 2.8 8.0 10.7 1.4e+02 2.6 10.7 3.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 PVD18901.1 - 3.5 7.4 8.7 6.1 6.6 0.5 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein CpXC PF14353.6 PVD18901.1 - 4.1 7.5 9.2 15 5.6 0.1 3.4 2 1 1 3 3 3 0 CpXC protein zf-C2H2_3rep PF18868.1 PVD18901.1 - 4.8 7.9 9.3 78 4.0 6.4 3.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 PVD18901.1 - 8.8 6.7 14.2 15 6.0 0.4 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 PVD18901.1 - 9.1 6.3 11.4 60 3.7 0.1 3.3 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Guanylate_cyc PF00211.20 PVD18902.1 - 5.5e-60 202.1 0.1 1.5e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD18902.1 - 2.2e-28 99.3 0.0 3.4e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD18902.1 - 5.9e-21 75.0 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 PVD18902.1 - 3e-07 30.1 0.3 6e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 Heme NO binding associated PhaP_Bmeg PF09602.10 PVD18902.1 - 0.057 13.4 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FMO-like PF00743.19 PVD18903.1 - 4.8e-45 154.0 0.0 5.6e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.19 PVD18904.1 - 6.1e-118 394.5 0.0 7.5e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 PVD18904.1 - 1.3e-16 60.7 0.0 2.2e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD18904.1 - 9.2e-14 51.4 0.0 4.9e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD18904.1 - 1.3e-08 34.4 0.1 6.2e-06 25.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PVD18904.1 - 1.5e-06 28.3 0.0 5.1e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PVD18904.1 - 4.7e-05 23.9 0.2 0.0065 17.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD18904.1 - 0.0014 17.5 0.1 0.0022 16.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 PVD18904.1 - 0.0023 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PVD18904.1 - 0.0035 17.0 0.2 2 7.9 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Peptidase_M17_N PF02789.17 PVD18904.1 - 0.0076 16.1 0.6 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain FAD_binding_3 PF01494.19 PVD18904.1 - 0.0082 15.4 0.1 0.48 9.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 PVD18904.1 - 0.011 15.3 0.0 20 4.7 0.0 3.1 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 PVD18904.1 - 0.015 14.6 0.0 0.87 8.8 0.0 2.7 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 PVD18904.1 - 0.021 14.8 0.1 1.2 9.2 0.0 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PVD18904.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PVD18904.1 - 0.032 14.7 0.3 21 5.6 0.0 3.1 4 0 0 4 4 4 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 PVD18904.1 - 0.054 12.8 0.9 0.087 12.1 0.0 1.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 PVD18904.1 - 0.14 11.6 0.1 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 PVD18904.1 - 0.23 11.5 0.1 10 6.2 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 PVD18905.1 - 0 1064.2 0.0 2e-159 531.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 PVD18905.1 - 1.3e-26 93.5 0.0 2.2e-11 43.5 0.0 3.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD18905.1 - 1.7e-23 83.3 0.0 1.4e-07 31.1 0.0 4.4 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD18905.1 - 5.3e-17 62.0 0.7 2e-05 23.9 0.0 5.4 6 0 0 6 6 6 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PVD18905.1 - 4e-14 52.6 0.0 1.9e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PVD18905.1 - 6e-08 31.8 0.3 0.008 14.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 PVD18905.1 - 8.4e-08 31.7 0.0 0.011 14.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 PVD18905.1 - 1.3e-07 32.1 3.0 0.044 14.4 0.0 4.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PVD18905.1 - 8.8e-06 25.8 0.2 3.1 7.8 0.0 4.8 4 2 0 4 4 4 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PVD18905.1 - 1.1e-05 25.0 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 PVD18905.1 - 1.6e-05 24.7 0.3 32 4.0 0.0 5.6 6 0 0 6 6 6 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PVD18905.1 - 3.3e-05 23.3 0.1 0.23 10.7 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PVD18905.1 - 0.0011 18.2 0.1 0.45 9.7 0.0 2.6 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 PVD18905.1 - 0.002 17.5 0.3 2.1 7.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Peptidase_M17_N PF02789.17 PVD18905.1 - 0.0046 16.8 5.8 1.3 8.9 0.0 3.3 4 0 0 4 4 3 2 Cytosol aminopeptidase family, N-terminal domain Glu_dehyd_C PF16912.5 PVD18905.1 - 0.0061 16.1 1.2 46 3.4 0.0 4.2 4 0 0 4 4 4 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 PVD18905.1 - 0.049 12.7 0.0 10 5.1 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 PVD18905.1 - 0.064 13.7 6.2 98 3.5 0.0 5.1 6 0 0 6 6 6 0 Putative NAD(P)-binding Rhabdo_M1 PF03342.13 PVD18905.1 - 0.23 10.8 0.0 19 4.5 0.0 2.2 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) FMO-like PF00743.19 PVD18906.1 - 4.5e-30 104.6 0.0 4.5e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.19 PVD18907.1 - 9.3e-50 169.5 0.7 3.2e-27 95.2 0.1 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD18907.1 - 1.6e-12 47.3 0.0 3e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD18907.1 - 1.1e-06 28.2 0.2 4.5e-06 26.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD18907.1 - 7.3e-06 25.4 0.3 0.00074 18.8 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_M17_N PF02789.17 PVD18907.1 - 0.016 15.0 0.1 0.094 12.6 0.0 2.1 1 1 1 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 PVD18907.1 - 0.078 12.5 0.5 16 4.9 0.0 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase IQ PF00612.27 PVD18908.1 - 7.6e-05 22.2 1.0 0.00028 20.4 1.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif FNIP_C PF14638.6 PVD18908.1 - 0.01 15.5 7.5 0.72 9.5 1.0 2.8 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus LINES_C PF14695.6 PVD18908.1 - 0.12 11.8 0.9 27 4.3 0.1 3.2 3 0 0 3 3 3 0 Lines C-terminus DUF4995 PF16386.5 PVD18908.1 - 0.12 12.3 0.4 25 4.9 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function ADC PF06314.11 PVD18908.1 - 0.19 11.3 0.2 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetoacetate decarboxylase (ADC) PSII_Pbs31 PF18240.1 PVD18908.1 - 0.21 12.0 5.4 7.9 7.0 0.3 3.7 3 0 0 3 3 3 0 Photosystem II Psb31 protein NikR_C PF08753.11 PVD18908.1 - 0.41 10.8 5.9 16 5.8 0.0 4.2 4 0 0 4 4 4 0 NikR C terminal nickel binding domain Flagellin_N PF00669.20 PVD18908.1 - 4.2 7.5 23.6 2.1 8.5 5.9 4.3 2 2 2 4 4 4 0 Bacterial flagellin N-terminal helical region CwsA PF10814.8 PVD18908.1 - 6.2 7.0 8.8 21 5.3 0.9 3.4 2 1 1 3 3 3 0 Cell wall synthesis protein CwsA EF-hand_7 PF13499.6 PVD18908.1 - 6.4 7.3 14.1 5 7.7 0.7 3.8 4 0 0 4 4 4 0 EF-hand domain pair BrkDBD PF09607.10 PVD18908.1 - 9.3 6.1 7.7 25 4.7 0.2 3.6 4 0 0 4 4 4 0 Brinker DNA-binding domain VWC PF00093.18 PVD18909.1 - 3.1e-13 49.8 15.3 5.5e-11 42.6 9.3 2.3 2 0 0 2 2 2 2 von Willebrand factor type C domain ETX_MTX2 PF03318.13 PVD18912.1 - 3.2e-09 36.9 3.1 4.5e-09 36.4 3.1 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 PVD18912.1 - 0.0002 20.7 0.1 0.00029 20.2 0.1 1.2 1 0 0 1 1 1 1 Aerolysin toxin ETX_MTX2 PF03318.13 PVD18913.1 - 7.5e-10 39.0 6.0 8.6e-10 38.8 6.0 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 PVD18913.1 - 0.00046 19.5 1.1 0.00056 19.2 1.1 1.0 1 0 0 1 1 1 1 Aerolysin toxin DUF945 PF06097.11 PVD18913.1 - 0.052 12.7 0.3 0.057 12.5 0.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) CDI PF02234.19 PVD18913.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor ETX_MTX2 PF03318.13 PVD18917.1 - 7.5e-10 39.0 7.5 1.3e-09 38.2 7.5 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 PVD18917.1 - 0.00035 19.9 1.4 0.00053 19.3 1.4 1.2 1 0 0 1 1 1 1 Aerolysin toxin ETX_MTX2 PF03318.13 PVD18918.1 - 1.2e-07 31.7 4.3 2.1e-07 31.0 4.3 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 PVD18918.1 - 0.0042 16.3 1.6 0.0066 15.7 1.6 1.2 1 0 0 1 1 1 1 Aerolysin toxin DUF3715 PF12509.8 PVD18918.1 - 0.041 13.9 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) zf-RING_2 PF13639.6 PVD18920.1 - 1e-12 48.2 11.9 1.9e-12 47.3 11.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PVD18920.1 - 4.2e-12 45.6 4.3 9.7e-12 44.4 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD18920.1 - 1.1e-07 31.6 12.2 1.8e-07 30.9 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD18920.1 - 3e-07 30.2 11.9 5.4e-07 29.4 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 PVD18920.1 - 1.2e-06 28.4 0.0 3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 PVD18920.1 - 9.5e-06 25.5 11.0 1.7e-05 24.7 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD18920.1 - 3.1e-05 24.2 13.5 0.00016 21.9 13.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PVD18920.1 - 7.6e-05 22.5 10.8 0.00014 21.6 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD18920.1 - 0.00015 21.7 12.0 0.00034 20.6 12.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD18920.1 - 0.00086 19.1 9.1 0.0018 18.1 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GT87 PF09594.10 PVD18920.1 - 0.021 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF3989 PF13150.6 PVD18920.1 - 0.029 14.1 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) zf-ANAPC11 PF12861.7 PVD18920.1 - 0.4 10.7 10.0 1.5 8.9 8.6 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PVD18920.1 - 0.77 10.0 8.9 2.1 8.6 8.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PVD18920.1 - 0.95 9.3 11.5 2.1 8.2 11.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 PVD18920.1 - 1.1 9.2 10.8 2.2 8.2 10.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 PVD18920.1 - 7.5 6.8 10.9 17 5.6 10.9 1.6 1 0 0 1 1 1 0 RING-variant domain DnaJ PF00226.31 PVD18921.1 - 1.1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain tRNA-synt_1c PF00749.21 PVD18922.1 - 3.8e-60 203.4 0.0 5.9e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain GGA_N-GAT PF18308.1 PVD18922.1 - 0.045 13.4 0.8 0.13 11.9 0.8 1.8 1 0 0 1 1 1 0 GGA N-GAT domain zf-RING_10 PF16685.5 PVD18923.1 - 2e-22 79.1 8.4 2e-22 79.1 8.4 2.6 2 0 0 2 2 2 1 zinc RING finger of MSL2 MSL2-CXC PF16682.5 PVD18923.1 - 5.7e-13 48.8 21.0 5.7e-13 48.8 21.0 2.5 2 0 0 2 2 2 1 CXC domain of E3 ubiquitin-protein ligase MSL2 PPR_2 PF13041.6 PVD18924.1 - 3.5e-16 59.1 4.7 4.9e-07 29.8 0.1 5.6 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 PVD18924.1 - 1.2e-14 54.1 4.4 4.2e-07 30.0 0.0 5.0 6 2 2 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 PVD18924.1 - 3.7e-09 36.3 0.4 2e-07 30.6 0.0 3.2 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PVD18924.1 - 2.5e-06 27.3 0.8 0.00039 20.5 0.1 4.4 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 PVD18924.1 - 0.0016 18.1 0.0 0.13 12.0 0.0 3.6 4 0 0 4 4 4 1 PPR repeat Dicty_REP PF05086.12 PVD18924.1 - 0.022 12.8 0.5 0.034 12.1 0.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 7tm_1 PF00001.21 PVD18925.1 - 8.6e-14 51.5 8.6 1.1e-13 51.1 8.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD18925.1 - 0.0019 17.9 2.5 0.0019 17.9 2.5 1.4 1 1 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 PVD18925.1 - 0.095 12.0 5.9 0.12 11.7 1.7 2.1 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Claudin_2 PF13903.6 PVD18926.1 - 0.00019 21.2 20.5 0.091 12.5 14.4 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Fim-adh_lectin PF09222.10 PVD18926.1 - 0.086 12.3 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain VirB8 PF04335.13 PVD18926.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 VirB8 protein DuoxA PF10204.9 PVD18926.1 - 1.3 8.0 8.1 0.095 11.7 2.5 1.8 2 0 0 2 2 2 0 Dual oxidase maturation factor Phage_holin_Dp1 PF16938.5 PVD18926.1 - 1.5 9.1 6.6 0.48 10.7 3.6 1.7 2 0 0 2 2 2 0 Putative phage holin Dp-1 Clc-like PF07062.12 PVD18926.1 - 2.1 7.7 16.1 0.26 10.7 0.2 2.7 2 1 0 2 2 2 0 Clc-like DUF2530 PF10745.9 PVD18926.1 - 4.7 7.5 8.5 3.8 7.8 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4131 PF13567.6 PVD18926.1 - 6.7 6.3 6.7 7.3 6.2 3.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Trp_oprn_chp PF09534.10 PVD18926.1 - 8.3 6.2 7.9 2.6 7.8 4.6 1.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PTCB-BRCT PF12738.7 PVD18928.1 - 3e-25 87.9 0.2 9.9e-18 63.9 0.2 3.5 3 0 0 3 3 3 2 twin BRCT domain RhoGEF PF00621.20 PVD18928.1 - 7.2e-19 68.7 0.0 1.3e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain BRCT PF00533.26 PVD18928.1 - 7.8e-14 51.8 0.0 1.7e-07 31.5 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD18928.1 - 0.0046 17.3 0.0 4.3 7.8 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BPL_LplA_LipB PF03099.19 PVD18929.1 - 1.4e-11 44.4 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RNase_H2-Ydr279 PF09468.10 PVD18930.1 - 2.5e-10 40.8 0.0 5.4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 PVD18930.1 - 3.9e-09 36.6 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Ribosomal_L7Ae PF01248.26 PVD18931.1 - 0.033 13.9 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family INT_SG_DDX_CT_C PF15300.6 PVD18932.1 - 1.8e-22 78.9 0.5 1.8e-22 78.9 0.5 1.9 2 0 0 2 2 2 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 PVD18932.1 - 7e-20 71.7 0.0 2.1e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD18932.1 - 0.00092 19.5 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PORR PF11955.8 PVD18932.1 - 0.052 12.5 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain LRR_8 PF13855.6 PVD18934.1 - 0.00025 20.8 0.3 0.00056 19.6 0.3 1.7 1 0 0 1 1 1 1 Leucine rich repeat fn3 PF00041.21 PVD18934.1 - 0.00088 19.6 0.0 0.0049 17.2 0.0 2.1 1 1 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.24 PVD18934.1 - 0.0027 18.1 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_4 PF12799.7 PVD18934.1 - 0.0049 17.2 0.7 0.017 15.5 0.1 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) fn3_2 PF16893.5 PVD18934.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.8 1 1 0 1 1 1 0 Fibronectin type III domain Ank_2 PF12796.7 PVD18936.1 - 1.2e-26 93.1 3.8 4.9e-12 46.3 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD18936.1 - 3.8e-17 62.4 1.6 6.9e-05 23.3 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD18936.1 - 5.2e-14 52.1 1.7 2.3e-09 37.3 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD18936.1 - 1.6e-13 50.5 6.3 3.2e-06 27.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PVD18936.1 - 8.6e-11 41.1 3.9 0.16 12.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat DUF2855 PF11017.8 PVD18941.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) EccE PF11203.8 PVD18941.1 - 0.062 13.6 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE RhoGEF PF00621.20 PVD18942.1 - 1e-45 156.2 3.3 1.9e-45 155.3 3.3 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 PVD18942.1 - 6.5e-12 45.1 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD18942.1 - 6.2e-10 38.5 1.0 1.6e-09 37.3 0.3 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD18942.1 - 2.4e-09 36.7 0.0 4.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 PVD18942.1 - 6.3e-09 36.3 0.3 1.8e-08 34.8 0.3 1.7 1 0 0 1 1 1 1 PH domain C2 PF00168.30 PVD18943.1 - 1.9e-26 92.3 0.2 1.2e-13 51.3 0.0 2.9 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 PVD18943.1 - 1.1e-15 57.9 0.0 2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PH PF00169.29 PVD18943.1 - 1.9e-12 47.6 2.0 1.1e-11 45.2 0.2 2.6 2 0 0 2 2 2 1 PH domain BTK PF00779.19 PVD18943.1 - 1.6e-11 43.8 0.7 3.2e-11 42.9 0.7 1.5 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.6 PVD18943.1 - 0.053 13.1 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 CEP76 C2 domain VEG PF06257.11 PVD18943.1 - 0.071 13.2 0.1 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Biofilm formation stimulator VEG Motile_Sperm PF00635.26 PVD18944.1 - 6.3e-08 32.4 0.7 1.2e-07 31.6 0.7 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain L6_membrane PF05805.12 PVD18944.1 - 0.47 10.0 7.1 0.32 10.5 1.9 2.1 1 1 1 2 2 2 0 L6 membrane protein Clat_adaptor_s PF01217.20 PVD18945.1 - 2.2e-56 189.7 0.7 2.6e-56 189.5 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 PVD18945.1 - 0.0069 15.0 0.3 0.0085 14.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) adh_short PF00106.25 PVD18946.1 - 1.1e-24 86.9 0.3 8.5e-24 84.1 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD18946.1 - 4e-17 62.6 0.0 2.2e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD18946.1 - 2.1e-12 47.3 0.1 3.3e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 PVD18946.1 - 0.0021 17.5 0.1 0.0058 16.1 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD18946.1 - 0.0068 15.9 0.1 0.015 14.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 PVD18946.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.32 PVD18947.1 - 1.6e-20 73.0 9.2 1.5e-06 28.8 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat FYVE PF01363.21 PVD18947.1 - 1.3e-15 57.3 7.3 2.9e-15 56.1 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nup160 PF11715.8 PVD18947.1 - 0.0093 14.7 1.2 3.9 6.0 0.1 3.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD18947.1 - 0.02 13.7 1.9 0.68 8.6 0.0 3.0 3 1 1 4 4 4 0 Nup133 N terminal like IBR PF01485.21 PVD18947.1 - 0.34 11.2 10.0 2 8.7 10.0 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 PVD18947.1 - 1.8 8.7 8.5 18 5.6 1.0 2.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-B_box PF00643.24 PVD18947.1 - 5.5 7.2 10.7 0.42 10.8 1.5 3.0 3 0 0 3 3 3 0 B-box zinc finger CEP63 PF17045.5 PVD18948.1 - 3.8e-46 158.2 64.3 3.8e-46 158.2 64.3 4.9 2 1 3 5 5 5 2 Centrosomal protein of 63 kDa HMMR_N PF15905.5 PVD18948.1 - 0.0023 17.5 31.2 0.0023 17.5 31.2 5.7 2 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 PVD18948.1 - 0.025 13.5 114.4 0.012 14.5 29.5 5.4 2 2 3 5 5 5 0 Spc7 kinetochore protein SWIRM-assoc_2 PF16496.5 PVD18952.1 - 0.3 9.9 3.1 0.35 9.7 3.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MSP1_C PF07462.11 PVD18952.1 - 0.91 8.1 4.4 1.6 7.4 3.4 1.5 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus TSC22 PF01166.18 PVD18953.1 - 2e-27 95.2 1.8 3.6e-27 94.5 1.8 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Fzo_mitofusin PF04799.13 PVD18953.1 - 0.0025 17.4 1.0 0.0034 16.9 1.0 1.1 1 0 0 1 1 1 1 fzo-like conserved region DivIC PF04977.15 PVD18953.1 - 0.007 16.1 1.1 0.012 15.3 1.1 1.4 1 0 0 1 1 1 1 Septum formation initiator YabA PF06156.13 PVD18953.1 - 0.0092 16.6 0.4 0.015 15.9 0.4 1.4 1 0 0 1 1 1 1 Initiation control protein YabA SOGA PF11365.8 PVD18953.1 - 0.013 16.6 0.4 0.019 16.1 0.4 1.3 1 0 0 1 1 1 0 Protein SOGA DUF2730 PF10805.8 PVD18953.1 - 0.059 13.5 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) K-box PF01486.17 PVD18953.1 - 0.078 13.2 1.0 0.13 12.4 1.0 1.3 1 0 0 1 1 1 0 K-box region BTB_2 PF02214.22 PVD18954.1 - 1.5e-14 54.1 0.0 3.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD18954.1 - 5.3e-10 39.1 8.7 5.3e-10 39.1 8.7 2.3 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 PVD18954.1 - 1.3e-09 37.6 18.8 6.8e-09 35.3 18.7 1.9 1 1 1 2 2 2 1 Ion transport protein DKCLD PF08068.12 PVD18955.1 - 5.3e-31 106.5 0.4 1.7e-30 104.9 0.3 1.9 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 PVD18955.1 - 6.9e-24 84.9 0.3 2.1e-21 76.8 0.3 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PVD18955.1 - 2.5e-20 72.4 0.1 5.4e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 PVD18955.1 - 4.8e-20 71.3 2.8 4.8e-20 71.3 2.8 1.8 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 PVD18955.1 - 0.00033 20.9 0.1 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain SR-25 PF10500.9 PVD18955.1 - 4.4 6.9 35.3 0.076 12.6 21.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein XPG_I PF00867.18 PVD18956.1 - 7.9e-24 83.8 0.0 6.4e-23 80.9 0.0 2.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PVD18956.1 - 7e-13 48.9 0.1 2.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain TT_ORF1 PF02956.14 PVD18958.1 - 6.3 5.3 9.8 7.4 5.1 9.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 EF-hand_7 PF13499.6 PVD18959.1 - 0.021 15.2 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 PVD18959.1 - 0.025 14.1 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 EF hand Mis12 PF05859.12 PVD18959.1 - 0.035 14.1 0.8 0.035 14.1 0.8 2.6 3 1 0 3 3 3 0 Mis12 protein APG6_N PF17675.1 PVD18959.1 - 0.13 12.8 8.0 0.3 11.6 8.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 PVD18959.1 - 3 8.8 14.2 53 4.8 14.2 2.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain fn3 PF00041.21 PVD18960.1 - 2.1e-86 284.4 8.6 4.5e-13 49.4 0.1 10.0 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD18960.1 - 2.3e-27 95.4 10.6 0.003 18.1 0.0 10.2 10 0 0 10 10 10 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD18960.1 - 5e-08 33.2 0.2 0.81 10.0 0.0 6.7 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 PVD18960.1 - 2.5e-06 27.8 0.0 88 3.6 0.0 8.0 9 0 0 9 9 9 0 Uncharacterised conserved protein (DUF2369) Arylsulfotran_N PF17425.2 PVD18960.1 - 0.059 13.4 0.0 6.8 6.8 0.0 3.3 3 0 0 3 3 3 0 Arylsulfotransferase Ig-like domain ABC_membrane PF00664.23 PVD18961.1 - 1.6e-67 228.0 22.4 2.1e-40 139.1 11.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD18961.1 - 6.1e-54 182.3 0.7 5.1e-29 101.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter Fis1_TPR_C PF14853.6 PVD18961.1 - 8.4e-22 77.0 2.0 8.4e-22 77.0 2.0 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 PVD18961.1 - 6e-14 51.4 0.0 1.4e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat SMC_N PF02463.19 PVD18961.1 - 5.6e-08 32.5 3.0 0.21 11.0 0.0 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD18961.1 - 2e-07 31.5 0.2 0.014 15.7 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PVD18961.1 - 2.3e-06 27.3 0.1 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD18961.1 - 7.2e-06 26.0 1.2 0.52 10.1 0.1 3.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 PVD18961.1 - 3.3e-05 23.9 0.3 0.055 13.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD18961.1 - 8.8e-05 22.5 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 PVD18961.1 - 0.00033 20.9 3.0 1.4 9.2 0.0 4.4 4 1 0 4 4 4 1 AAA domain T2SSE PF00437.20 PVD18961.1 - 0.0016 17.6 0.0 0.097 11.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 PVD18961.1 - 0.0093 16.5 3.6 0.26 11.7 0.0 3.1 4 0 0 4 4 2 1 AAA domain Drc1-Sld2 PF11719.8 PVD18961.1 - 0.012 15.2 1.1 0.018 14.6 1.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Dynamin_N PF00350.23 PVD18961.1 - 0.016 15.3 6.9 0.45 10.5 0.8 3.4 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 PVD18961.1 - 0.02 14.4 0.0 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 PVD18961.1 - 0.028 14.0 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PVD18961.1 - 0.065 13.0 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TPR_2 PF07719.17 PVD18961.1 - 0.085 13.0 0.2 0.085 13.0 0.2 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat DUF815 PF05673.13 PVD18961.1 - 0.11 11.7 0.1 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.11 PVD18961.1 - 0.13 11.1 0.1 7 5.5 0.2 2.4 2 0 0 2 2 2 0 PrkA AAA domain cobW PF02492.19 PVD18961.1 - 0.3 10.7 1.5 6.4 6.3 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 PVD18961.1 - 0.51 10.4 0.0 0.51 10.4 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Glypican PF01153.19 PVD18962.1 - 1.6e-07 30.6 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glypican Serglycin PF04360.12 PVD18962.1 - 2.2e-06 27.7 0.1 2.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Serglycin Glypican PF01153.19 PVD18963.1 - 8.2e-17 61.2 0.0 8.2e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Glypican Glypican PF01153.19 PVD18965.1 - 2.4e-97 327.1 0.8 3e-97 326.8 0.8 1.0 1 0 0 1 1 1 1 Glypican RecR PF02132.15 PVD18965.1 - 0.087 12.4 2.1 0.3 10.7 2.1 1.9 1 0 0 1 1 1 0 RecR protein ENT PF03735.14 PVD18968.1 - 1.5e-29 101.8 1.9 3.6e-29 100.6 1.9 1.7 1 0 0 1 1 1 1 ENT domain RRM_1 PF00076.22 PVD18968.1 - 5.2e-09 35.8 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlxA PF14282.6 PVD18968.1 - 0.00013 21.9 9.9 0.00013 21.9 9.9 3.8 3 1 1 4 4 4 1 FlxA-like protein RRM_7 PF16367.5 PVD18968.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif SWIRM-assoc_1 PF16495.5 PVD18968.1 - 0.24 11.4 7.7 0.88 9.6 7.7 2.1 1 0 0 1 1 1 0 SWIRM-associated region 1 UPF0242 PF06785.11 PVD18968.1 - 0.24 11.5 16.3 0.77 9.8 16.3 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_5 PF07728.14 PVD18969.1 - 1.5e-99 329.5 0.0 2e-38 131.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PVD18969.1 - 6e-08 32.8 0.0 0.00078 19.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 PVD18969.1 - 1.7e-07 31.8 0.0 0.4 11.0 0.0 4.8 4 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 PVD18969.1 - 3e-06 27.6 0.1 0.04 14.2 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 PVD18969.1 - 7.9e-06 26.3 0.4 0.053 13.9 0.0 3.9 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 PVD18969.1 - 2.1e-05 24.7 0.0 0.18 11.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 PVD18969.1 - 9.5e-05 22.0 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 PVD18969.1 - 0.00023 20.6 0.0 1.1 8.6 0.0 3.0 2 0 0 2 2 2 2 Bacterial TniB protein AAA_3 PF07726.11 PVD18969.1 - 0.00027 20.8 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PVD18969.1 - 0.00055 20.5 0.2 1.2 9.7 0.0 3.7 3 1 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.21 PVD18969.1 - 0.0038 16.7 0.1 5.8 6.2 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI CbbQ_C PF08406.10 PVD18969.1 - 0.012 15.9 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal VWA_2 PF13519.6 PVD18969.1 - 0.014 16.0 0.0 0.058 14.1 0.0 2.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Roc PF08477.13 PVD18969.1 - 0.015 15.5 0.2 1.3 9.2 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 PVD18969.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 PVD18969.1 - 0.03 14.7 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 PVD18969.1 - 0.031 14.2 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 PVD18969.1 - 0.057 13.4 0.0 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 PVD18969.1 - 0.06 13.0 0.0 7.1 6.2 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 PVD18969.1 - 0.06 13.1 0.0 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 PVD18969.1 - 0.13 12.4 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 PVD18969.1 - 0.2 10.8 0.2 0.61 9.1 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain TNF PF00229.18 PVD18970.1 - 7.4e-16 58.2 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Tox-ART-HYD1 PF15633.6 PVD18971.1 - 0.00012 22.7 0.0 0.00014 22.5 0.0 1.1 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase Tox-ART-HYD1 PF15633.6 PVD18972.1 - 1.8e-07 31.7 0.1 3e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase FYVE PF01363.21 PVD18972.1 - 1.8e-05 24.7 1.3 2.7e-05 24.2 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger LEDGF PF11467.8 PVD18973.1 - 0.3 10.7 5.7 0.12 12.0 0.7 2.6 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) TNF PF00229.18 PVD18974.1 - 1.2e-28 99.6 0.1 1.4e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 PVD18974.1 - 0.0071 16.6 0.6 0.74 10.0 0.0 2.2 1 1 0 2 2 2 2 C1q domain DUF2147 PF09917.9 PVD18974.1 - 0.08 13.6 0.0 0.17 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) 7tm_1 PF00001.21 PVD18977.1 - 0.022 14.1 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SUIM_assoc PF16619.5 PVD18978.1 - 2.5 8.2 12.9 3.8 7.7 12.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DnaJ PF00226.31 PVD18979.1 - 4.4e-24 84.4 0.2 1.2e-23 82.9 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 PVD18979.1 - 4.7e-05 23.1 0.4 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPT PF13446.6 PVD18979.1 - 0.017 15.0 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein RRM_5 PF13893.6 PVD18979.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CotJB PF12652.7 PVD18979.1 - 0.096 12.9 0.2 11 6.3 0.0 3.4 2 1 1 3 3 3 0 CotJB protein DUF4736 PF15883.5 PVD18979.1 - 0.39 10.4 4.4 0.87 9.3 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4736) FapA PF03961.13 PVD18979.1 - 0.74 8.4 8.8 1.1 7.8 8.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc24 PF08286.11 PVD18979.1 - 0.95 9.7 13.2 0.33 11.2 2.1 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 PVD18979.1 - 2.8 5.7 5.9 3.4 5.5 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 7tm_1 PF00001.21 PVD18981.1 - 3.9e-20 72.3 15.2 3.9e-20 72.3 15.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sulfotransfer_2 PF03567.14 PVD18982.1 - 7.7e-21 75.1 0.0 1e-18 68.2 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family DUF4164 PF13747.6 PVD18985.1 - 0.0048 17.1 0.4 0.0057 16.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) DUF3740 PF12548.8 PVD18985.1 - 0.005 17.3 1.4 0.0059 17.1 1.4 1.1 1 0 0 1 1 1 1 Sulfatase protein DUF3915 PF13054.6 PVD18985.1 - 0.055 13.5 1.2 0.068 13.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TctB PF07331.11 PVD18986.1 - 0.042 14.1 3.5 0.13 12.5 1.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Claudin_3 PF06653.11 PVD18986.1 - 0.44 10.5 9.1 0.24 11.3 0.7 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Clc-like PF07062.12 PVD18986.1 - 1.2 8.6 8.7 4 6.9 8.7 1.8 1 1 0 1 1 1 0 Clc-like DUF1505 PF07403.11 PVD18986.1 - 1.7 8.8 6.3 11 6.3 6.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) zf-CCHC PF00098.23 PVD18987.1 - 0.00088 19.2 2.3 0.00088 19.2 2.3 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.6 PVD18987.1 - 0.013 15.3 7.0 0.28 10.9 0.6 2.6 2 0 0 2 2 2 0 Zinc knuckle VIGSSK PF14773.6 PVD18987.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.6 2 1 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal zf-CCHC_5 PF14787.6 PVD18987.1 - 2.8 7.7 14.6 0.7 9.6 2.7 2.9 1 1 2 3 3 3 0 GAG-polyprotein viral zinc-finger DUF2181 PF10223.9 PVD18989.1 - 4.9e-122 406.0 0.0 2.2e-78 263.1 0.2 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2181) Ras PF00071.22 PVD18990.1 - 3.1e-53 179.7 0.0 3.6e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD18990.1 - 1.1e-21 77.3 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD18990.1 - 6.1e-10 38.8 0.0 7.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD18990.1 - 0.017 14.7 0.2 0.03 13.9 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain fn3 PF00041.21 PVD18991.1 - 2.7e-21 75.7 1.1 4.3e-07 30.2 0.2 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.10 PVD18991.1 - 0.0001 22.6 0.0 0.47 10.8 0.1 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 PVD18991.1 - 0.0014 19.2 9.4 0.55 10.8 0.1 4.2 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain WAP PF00095.21 PVD18992.1 - 2.6e-10 40.5 14.7 2.6e-10 40.5 14.7 3.4 4 1 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ion_trans PF00520.31 PVD18994.1 - 7.6e-22 77.7 14.1 9.5e-22 77.4 14.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD18994.1 - 5.3e-06 26.3 0.6 1.4e-05 25.0 0.6 1.7 1 0 0 1 1 1 1 Ion channel DHHC PF01529.20 PVD18994.1 - 0.033 14.3 0.2 0.033 14.3 0.2 2.3 1 1 2 3 3 3 0 DHHC palmitoyltransferase cNMP_binding PF00027.29 PVD18997.1 - 2.3e-14 53.2 0.0 4.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mto2_bdg PF12808.7 PVD18997.1 - 0.13 12.6 2.6 0.18 12.2 0.8 2.1 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.21 PVD18997.1 - 0.74 10.0 4.4 0.38 10.9 1.9 1.8 2 0 0 2 2 2 0 bZIP transcription factor FAM194 PF14977.6 PVD18998.1 - 2.6e-51 173.8 0.0 4.2e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein UPF0167 PF03691.14 PVD18998.1 - 0.035 13.9 0.0 0.34 10.7 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) RRM_1 PF00076.22 PVD18999.1 - 4.1e-19 68.2 0.0 8.7e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD18999.1 - 1.1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 PVD18999.1 - 0.0057 16.2 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 PVD18999.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) GpcrRhopsn4 PF10192.9 PVD19000.1 - 7.8e-17 61.5 0.0 1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 PVD19000.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor zf-C2H2_3rep PF18868.1 PVD19001.1 - 0.016 15.8 3.2 0.66 10.7 0.7 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 PVD19001.1 - 0.017 15.9 11.6 1 10.4 3.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD19001.1 - 0.073 13.5 7.1 0.43 11.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain UNC45-central PF11701.8 PVD19001.1 - 0.091 12.7 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF629 PF04780.12 PVD19001.1 - 0.18 10.3 6.4 0.37 9.3 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) DUF2310 PF10071.9 PVD19001.1 - 0.2 10.9 2.3 0.28 10.4 2.3 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) C1_2 PF03107.16 PVD19001.1 - 0.46 10.8 8.3 8 6.9 7.3 2.6 2 1 0 2 2 2 0 C1 domain zf-C2H2 PF00096.26 PVD19001.1 - 1.5 9.4 12.1 0.76 10.4 2.7 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 PVD19001.1 - 2.5 8.4 9.0 2.4 8.5 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon YPEB PF14620.6 PVD19003.1 - 0.0028 17.1 0.9 0.0056 16.1 0.9 1.4 1 0 0 1 1 1 1 YpeB sporulation HTH_1 PF00126.27 PVD19003.1 - 0.028 14.4 1.5 0.17 11.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family GIT_CC PF16559.5 PVD19003.1 - 0.13 12.2 0.6 11 5.9 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ribosomal_L2_C PF03947.18 PVD19005.1 - 1.4e-46 157.8 3.7 2.3e-46 157.1 3.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PVD19005.1 - 7e-10 38.7 0.1 6.7e-09 35.6 0.0 2.5 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain HEAT PF02985.22 PVD19006.1 - 1.9e-14 52.5 6.1 0.26 11.7 0.0 7.1 6 0 0 6 6 6 5 HEAT repeat HEAT_2 PF13646.6 PVD19006.1 - 1.8e-08 34.7 2.9 0.019 15.4 0.1 4.6 2 1 3 5 5 5 3 HEAT repeats Cnd1 PF12717.7 PVD19006.1 - 1.8e-07 31.3 2.6 0.18 11.8 0.2 4.6 2 1 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PVD19006.1 - 2e-06 26.7 0.3 0.34 9.4 0.1 3.3 2 1 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 PVD19006.1 - 0.0022 18.5 5.6 7.7 7.1 0.0 5.7 4 1 1 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 PVD19006.1 - 0.0041 17.3 1.3 0.34 11.1 0.1 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 PVD19006.1 - 2.7 7.7 8.2 2.8 7.6 0.0 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) DUF4498 PF14926.6 PVD19007.1 - 5.4e-63 212.6 9.0 2.4e-39 135.1 0.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4498) Stap_Strp_toxin PF01123.20 PVD19007.1 - 0.057 14.3 0.5 0.21 12.5 0.1 2.0 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain Lectin_C PF00059.21 PVD19008.1 - 3.3e-05 24.6 0.2 6.2e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 PVD19008.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 PVD19008.1 - 0.015 15.5 16.0 0.022 15.0 2.9 3.6 4 0 0 4 4 4 0 Low-density lipoprotein receptor domain class A TNF PF00229.18 PVD19009.1 - 1.7e-11 44.2 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family MFS_1 PF07690.16 PVD19010.1 - 2.3e-23 82.7 51.3 1.5e-14 53.7 27.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RT_RNaseH PF17917.1 PVD19011.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CAF1A PF12253.8 PVD19011.1 - 0.47 10.7 4.8 0.24 11.6 2.1 1.9 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A TNF PF00229.18 PVD19013.1 - 5.8e-15 55.4 0.1 9.5e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Ntox5 PF15543.6 PVD19013.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 5 Rib PF08428.10 PVD19013.1 - 0.11 12.5 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Rib/alpha-like repeat SPRY PF00622.28 PVD19015.1 - 1.1e-19 70.7 0.0 2.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PCI PF01399.27 PVD19016.1 - 5.3e-17 62.2 0.6 1.1e-16 61.2 0.6 1.6 1 0 0 1 1 1 1 PCI domain Spc24 PF08286.11 PVD19016.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TNRC6-PABC_bdg PF16608.5 PVD19017.1 - 0.043 13.5 0.2 0.051 13.3 0.2 1.1 1 0 0 1 1 1 0 TNRC6-PABC binding domain AAA_30 PF13604.6 PVD19018.1 - 0.00013 21.8 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NERD PF08378.11 PVD19018.1 - 0.0035 17.8 0.2 0.012 16.1 0.1 2.0 2 0 0 2 2 2 1 Nuclease-related domain AAA_16 PF13191.6 PVD19018.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PVD19018.1 - 0.0045 17.3 0.2 0.068 13.4 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA PF00004.29 PVD19018.1 - 0.037 14.4 0.1 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PVD19018.1 - 0.12 12.9 0.5 0.61 10.5 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PVD19018.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Senescence PF06911.12 PVD19018.1 - 0.22 11.8 4.5 0.47 10.8 4.5 1.4 1 0 0 1 1 1 0 Senescence-associated protein NERD PF08378.11 PVD19019.1 - 0.0015 19.0 0.0 0.0045 17.4 0.0 1.8 1 0 0 1 1 1 1 Nuclease-related domain vATP-synt_E PF01991.18 PVD19019.1 - 0.024 14.1 0.2 0.061 12.7 0.2 1.6 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF2063 PF09836.9 PVD19019.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain AAA_22 PF13401.6 PVD19020.1 - 0.00087 19.6 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PVD19020.1 - 0.0037 17.3 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PVD19020.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD19020.1 - 0.006 17.0 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 PVD19020.1 - 0.0069 16.8 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 PVD19020.1 - 0.0076 16.6 0.0 0.095 13.0 0.0 2.7 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 PVD19020.1 - 0.02 14.9 0.1 0.91 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PVD19020.1 - 0.022 15.3 0.3 0.19 12.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 PVD19020.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD19020.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SWIRM-assoc_2 PF16496.5 PVD19020.1 - 0.15 10.9 1.6 0.27 10.1 1.6 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PhoH PF02562.16 PVD19020.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 PVD19021.1 - 6.3e-05 23.3 0.2 0.0012 19.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD19021.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PVD19021.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD19021.1 - 0.031 14.7 0.1 0.23 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 PVD19021.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD19021.1 - 0.12 13.0 1.3 0.56 10.8 0.4 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD19021.1 - 0.16 11.8 1.1 0.51 10.2 1.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 PVD19021.1 - 0.18 12.2 0.2 0.74 10.2 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hormone_recep PF00104.30 PVD19022.1 - 3.4e-10 39.8 0.0 7.5e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Orthopox_A5L PF06193.11 PVD19022.1 - 0.022 14.2 0.7 0.038 13.4 0.7 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like IlvB_leader PF08049.11 PVD19026.1 - 0.32 11.0 11.3 0.64 10.0 11.3 1.6 1 0 0 1 1 1 0 IlvB leader peptide zf-C3HC4_3 PF13920.6 PVD19027.1 - 1.8e-09 37.3 12.0 3.7e-09 36.3 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD19027.1 - 0.0059 16.4 11.4 0.016 15.0 11.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD19027.1 - 0.019 14.9 14.6 0.044 13.8 14.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HAP1_N PF04849.13 PVD19027.1 - 0.049 12.8 0.7 0.072 12.3 0.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF2321 PF10083.9 PVD19027.1 - 0.11 12.1 2.6 0.28 10.8 2.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF2039 PF10217.9 PVD19027.1 - 0.17 12.2 6.8 0.34 11.3 6.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-H2C2_2 PF13465.6 PVD19028.1 - 2.2e-15 56.3 4.9 9.1e-08 32.2 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD19028.1 - 1.6e-11 44.0 11.0 7.4e-06 26.1 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD19028.1 - 3e-09 36.9 10.4 0.00038 21.1 1.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD19028.1 - 6e-05 23.2 2.0 0.027 14.7 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF1390 PF07150.11 PVD19028.1 - 0.00038 20.2 1.0 0.00057 19.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1390) zf-C2H2_11 PF16622.5 PVD19028.1 - 0.0013 18.5 2.9 0.44 10.3 0.1 2.9 2 0 0 2 2 2 2 zinc-finger C2H2-type DZR PF12773.7 PVD19028.1 - 0.0013 18.7 0.4 0.0013 18.7 0.4 2.2 2 1 0 2 2 2 1 Double zinc ribbon zf_UBZ PF18439.1 PVD19028.1 - 0.0017 17.9 2.2 0.35 10.5 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 PVD19028.1 - 0.0022 17.9 0.4 0.0022 17.9 0.4 3.8 4 1 0 4 4 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 PVD19028.1 - 0.0045 17.6 0.3 0.015 15.9 0.0 2.0 2 0 0 2 2 2 1 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 PVD19028.1 - 0.01 15.9 1.1 0.89 9.7 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain XPA_N PF01286.18 PVD19028.1 - 0.017 15.2 2.6 0.32 11.1 0.3 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 PVD19028.1 - 0.038 14.7 0.9 0.065 14.0 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbon family zf-trcl PF13451.6 PVD19028.1 - 0.049 13.5 0.7 6 6.8 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Rubredoxin_2 PF18073.1 PVD19028.1 - 0.11 12.3 2.5 8.2 6.2 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-AN1 PF01428.16 PVD19028.1 - 0.16 12.1 2.9 10 6.4 0.1 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger CpXC PF14353.6 PVD19028.1 - 0.19 11.8 1.1 9 6.4 0.1 2.2 1 1 1 2 2 2 0 CpXC protein DUF629 PF04780.12 PVD19028.1 - 0.46 9.0 1.2 0.53 8.7 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 PVD19028.1 - 0.49 10.1 5.7 7.7 6.3 0.2 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_5 PF13719.6 PVD19028.1 - 0.67 9.8 2.4 1.1 9.1 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-met PF12874.7 PVD19028.1 - 6.8 7.2 8.7 0.57 10.7 1.5 2.8 3 0 0 3 3 2 0 Zinc-finger of C2H2 type Filamin PF00630.19 PVD19030.1 - 7.3e-208 675.6 12.0 3.7e-14 53.4 0.0 19.6 19 1 0 19 19 19 19 Filamin/ABP280 repeat CH PF00307.31 PVD19030.1 - 1.7e-51 173.0 0.3 3.4e-23 81.9 1.3 3.4 3 0 0 3 3 3 3 Calponin homology (CH) domain DUF5060 PF16586.5 PVD19030.1 - 4.8e-09 36.4 4.8 4.4 7.7 0.0 11.4 13 1 0 13 13 12 1 Domain of unknown function (DUF5060) CAMSAP_CH PF11971.8 PVD19030.1 - 9.4e-09 35.0 0.3 0.087 12.7 0.0 3.5 3 0 0 3 3 3 3 CAMSAP CH domain Big_3_5 PF16640.5 PVD19030.1 - 8.1e-08 32.3 13.0 2.6 8.3 0.3 11.0 12 1 1 13 13 13 1 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 PVD19030.1 - 1.9e-06 28.1 4.9 4.1 7.8 0.1 8.1 10 0 0 10 10 9 1 Invasin, domain 3 YtkA PF13115.6 PVD19030.1 - 0.00046 20.7 1.1 24 5.6 0.1 7.7 9 0 0 9 9 9 0 YtkA-like CBM60 PF16841.5 PVD19030.1 - 0.0011 19.3 4.0 1.5 9.3 0.0 5.0 6 0 0 6 6 4 2 Ca-dependent carbohydrate-binding module xylan-binding End_N_terminal PF12218.8 PVD19030.1 - 0.02 14.6 0.0 4.4 7.1 0.0 4.2 5 0 0 5 5 5 0 N terminal extension of bacteriophage endosialidase PapC_N PF13954.6 PVD19030.1 - 0.025 14.6 0.0 48 3.9 0.0 4.4 4 0 0 4 4 4 0 PapC N-terminal domain PPC PF04151.15 PVD19030.1 - 0.028 15.5 7.6 55 5.0 0.0 7.2 10 0 0 10 10 7 0 Bacterial pre-peptidase C-terminal domain DUF3971 PF13116.6 PVD19030.1 - 0.21 11.1 0.0 0.98 8.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function Big_8 PF17961.1 PVD19030.1 - 0.34 11.1 2.0 27 5.0 0.1 4.2 5 0 0 5 5 5 0 Bacterial Ig domain EGF PF00008.27 PVD19033.1 - 6.9e-28 96.6 82.4 1.8e-07 31.3 9.3 6.7 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 PVD19033.1 - 4.6e-18 65.1 71.7 8.7e-05 23.0 6.1 8.2 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 PVD19033.1 - 6.4e-06 26.4 95.7 0.15 12.5 9.5 6.7 6 0 0 6 6 6 6 EGF-like domain EGF_CA PF07645.15 PVD19033.1 - 2e-05 24.7 85.3 0.0019 18.4 8.1 6.5 3 2 3 6 6 6 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD19033.1 - 0.00023 21.4 74.3 0.13 12.5 7.7 7.3 3 3 4 7 7 7 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PVD19033.1 - 0.012 15.8 21.2 0.023 14.9 10.0 7.3 5 3 1 6 6 6 0 EGF domain cEGF PF12662.7 PVD19033.1 - 0.015 15.2 1.8 0.015 15.2 1.8 7.3 8 1 0 8 8 8 0 Complement Clr-like EGF-like VWD PF00094.25 PVD19036.1 - 2.8e-12 47.2 0.6 6.3e-12 46.0 0.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 PVD19036.1 - 0.019 15.4 0.8 0.019 15.4 0.8 2.4 2 0 0 2 2 2 0 C8 domain RGM_C PF06534.13 PVD19036.1 - 0.033 13.7 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Dyp_perox PF04261.12 PVD19037.1 - 4e-09 35.9 0.0 4.8e-06 25.8 0.0 3.2 2 1 0 2 2 2 2 Dyp-type peroxidase family 3HCDH_N PF02737.18 PVD19038.1 - 1.1e-42 145.9 0.0 1.6e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PVD19038.1 - 1.1e-06 28.9 0.1 2.5e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH PF00725.22 PVD19038.1 - 3.8e-06 27.4 0.0 1.1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PilJ PF13675.6 PVD19038.1 - 0.013 15.5 0.8 0.031 14.3 0.1 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term adh_short PF00106.25 PVD19038.1 - 0.074 12.5 0.2 0.14 11.6 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 PVD19038.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAIM1 PF06905.13 PVD19039.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Utp21 PF04192.12 PVD19040.1 - 3e-57 193.8 0.1 4.2e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 PVD19040.1 - 5.1e-22 77.8 20.4 3.3e-08 34.0 0.2 9.8 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD19040.1 - 6.9e-13 48.7 0.1 0.022 15.1 0.0 6.3 2 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PVD19040.1 - 0.048 12.2 0.1 0.097 11.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Rhomboid PF01694.22 PVD19041.1 - 1.7e-23 83.3 15.7 3.7e-23 82.2 15.7 1.5 1 0 0 1 1 1 1 Rhomboid family DUF4079 PF13301.6 PVD19041.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Sec34 PF04136.15 PVD19042.1 - 2.5e-51 173.5 10.4 2.5e-51 173.5 10.4 2.8 3 0 0 3 3 3 1 Sec34-like family SKA2 PF16740.5 PVD19042.1 - 0.0083 15.9 0.4 0.043 13.6 0.4 2.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Syntaxin-18_N PF10496.9 PVD19042.1 - 0.099 12.9 0.1 0.35 11.2 0.1 1.9 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ACP53EA PF06313.11 PVD19042.1 - 0.13 12.5 1.6 0.94 9.7 0.1 3.0 3 0 0 3 3 3 0 Drosophila ACP53EA protein Baculo_PEP_C PF04513.12 PVD19042.1 - 0.35 10.9 7.4 0.37 10.8 3.8 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S28 PF05577.12 PVD19043.1 - 4.8e-152 506.7 4.4 5.5e-152 506.5 4.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 PVD19043.1 - 1.7e-09 37.7 1.6 4.1e-09 36.4 1.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD19043.1 - 0.0006 19.1 0.0 0.0011 18.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 PVD19043.1 - 0.069 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 PH PF00169.29 PVD19045.1 - 4.4e-13 49.7 0.0 6.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD19045.1 - 6.1e-05 23.4 0.1 0.00011 22.6 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain Tape_meas_lam_C PF09718.10 PVD19046.1 - 0.0069 16.5 0.0 0.049 13.8 0.0 2.3 2 0 0 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) NTF2 PF02136.20 PVD19046.1 - 0.069 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4795 PF16043.5 PVD19046.1 - 0.25 10.9 1.3 0.37 10.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 PVD19047.1 - 6.3e-05 23.1 4.8 0.0045 17.0 0.0 3.1 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 PVD19047.1 - 0.0032 17.4 0.7 0.015 15.2 0.7 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain 7TMR-HDED PF07697.11 PVD19047.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.5 1 1 1 2 2 2 0 7TM-HD extracellular Collagen_mid PF15984.5 PVD19047.1 - 0.11 12.2 9.9 0.19 11.5 4.9 2.8 1 1 1 2 2 2 0 Bacterial collagen, middle region NOD PF06816.13 PVD19047.1 - 0.38 10.4 3.3 6 6.6 0.1 3.8 4 0 0 4 4 4 0 NOTCH protein zf-RING_9 PF13901.6 PVD19048.1 - 2.8e-66 223.5 10.0 2.8e-66 223.5 10.0 2.0 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 PVD19048.1 - 1.3e-09 38.2 0.1 3.9e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 RUN domain Prok-RING_1 PF14446.6 PVD19048.1 - 1.4 8.9 9.5 0.32 10.9 5.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 PVD19048.1 - 1.8 8.8 14.8 0.15 12.2 1.0 2.9 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.26 PVD19049.1 - 8.9e-27 92.0 45.0 6.9e-07 29.4 2.6 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD19049.1 - 4.1e-24 83.9 49.6 5.2e-08 33.0 0.6 8.4 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD19049.1 - 2.8e-19 68.1 44.9 0.00046 20.8 2.5 8.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD19049.1 - 4.8e-09 35.8 17.8 0.042 13.6 0.8 5.0 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD19049.1 - 1.3e-06 28.2 49.5 0.00023 21.1 1.2 7.3 7 1 0 7 7 7 4 C2H2-type zinc finger DZR PF12773.7 PVD19049.1 - 1.2e-05 25.2 23.7 0.34 11.0 0.3 4.8 4 0 0 4 4 4 4 Double zinc ribbon GAGA PF09237.11 PVD19049.1 - 0.0053 16.5 15.1 0.045 13.6 0.1 4.1 4 0 0 4 4 4 2 GAGA factor zf-C2H2_jaz PF12171.8 PVD19049.1 - 0.015 15.6 32.3 0.035 14.4 0.3 6.5 7 0 0 7 7 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD19049.1 - 0.026 14.8 5.5 0.026 14.8 5.5 6.1 5 2 2 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 PVD19049.1 - 0.039 14.3 11.9 0.45 10.9 0.2 4.2 2 1 2 5 5 5 0 zinc-finger-containing domain zf_UBZ PF18439.1 PVD19049.1 - 0.044 13.4 22.5 0.24 11.0 0.0 6.8 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger GATA PF00320.27 PVD19049.1 - 0.52 10.0 10.9 1.4 8.6 0.1 4.9 5 0 0 5 5 5 0 GATA zinc finger Zn_ribbon_recom PF13408.6 PVD19049.1 - 0.93 10.1 17.0 15 6.2 2.0 5.1 4 1 0 4 4 4 0 Recombinase zinc beta ribbon domain zinc_ribbon_15 PF17032.5 PVD19049.1 - 1.7 9.4 24.0 3.5 8.4 1.2 5.0 2 1 4 6 6 6 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 PVD19049.1 - 3.4 7.4 33.1 4.2 7.1 1.2 5.9 2 2 3 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain CpXC PF14353.6 PVD19049.1 - 3.7 7.6 16.6 5.5 7.1 0.2 5.6 2 1 4 6 6 6 0 CpXC protein zf-H2C2_5 PF13909.6 PVD19049.1 - 6.5 6.6 31.2 2.8 7.8 0.4 6.8 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-ribbon_3 PF13248.6 PVD19049.1 - 7 6.2 16.5 15 5.2 0.0 6.0 6 0 0 6 6 6 0 zinc-ribbon domain Aldedh PF00171.22 PVD19050.1 - 1.1e-171 571.5 0.0 1.2e-171 571.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MlaC PF05494.12 PVD19050.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 MlaC protein Acyl-CoA_dh_1 PF00441.24 PVD19051.1 - 1.9e-42 145.0 5.1 7.6e-40 136.5 2.8 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PVD19051.1 - 8.6e-25 86.8 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD19051.1 - 7.3e-19 68.5 0.1 5e-18 65.8 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD19051.1 - 2.2e-14 53.9 1.4 1.2e-12 48.2 0.4 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain V_ATPase_I PF01496.19 PVD19051.1 - 0.0065 14.5 0.3 0.011 13.7 0.3 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Mor PF08765.11 PVD19051.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Mor transcription activator family Nuc_deoxyrib_tr PF05014.15 PVD19052.1 - 1.6e-06 28.1 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyrib_tr PF05014.15 PVD19053.1 - 2.4e-16 59.9 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Crust_neurohorm PF01147.17 PVD19056.1 - 0.27 11.1 3.5 0.33 10.8 0.1 2.4 2 1 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zf-C2H2_12 PF18658.1 PVD19057.1 - 0.0038 16.8 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-BED PF02892.15 PVD19057.1 - 0.019 15.0 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger Nuc_deoxyrib_tr PF05014.15 PVD19058.1 - 8.5e-17 61.4 0.0 9.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Glycos_trans_3N PF02885.17 PVD19059.1 - 0.018 14.9 0.0 0.47 10.4 0.0 2.5 1 1 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Spc24 PF08286.11 PVD19059.1 - 0.051 13.8 1.1 0.093 13.0 1.1 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TSP_1 PF00090.19 PVD19060.1 - 1.2e-12 47.8 17.3 9.8e-11 41.7 8.2 3.3 4 1 0 4 4 4 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 PVD19060.1 - 1.8e-08 34.4 7.6 1.8e-08 34.4 7.6 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A tRNA-synt_1g PF09334.11 PVD19061.1 - 1.7e-110 369.4 0.3 2.4e-109 365.7 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PVD19061.1 - 1e-28 100.0 4.6 2.1e-11 42.8 0.3 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PVD19061.1 - 6.4e-11 42.2 0.0 6.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 PVD19061.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 PVD19061.1 - 0.0036 16.3 0.0 0.0089 15.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) BRCC36_C PF18110.1 PVD19061.1 - 0.091 12.9 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain Fumble PF03630.14 PVD19062.1 - 1.1e-133 445.6 0.0 1.3e-133 445.2 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 PVD19062.1 - 4.6e-39 134.4 0.0 7e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 TMEM164 PF14808.6 PVD19063.1 - 7.5e-105 349.9 4.0 9.2e-105 349.6 4.0 1.1 1 0 0 1 1 1 1 TMEM164 family Voldacs PF03517.13 PVD19064.1 - 1.3e-34 119.3 4.3 1.8e-34 118.9 4.3 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Citrate_synt PF00285.21 PVD19064.1 - 0.00023 20.4 0.1 0.00029 20.0 0.1 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pep1_7 PF17232.2 PVD19064.1 - 0.3 11.6 7.1 1.4 9.5 1.0 2.3 1 1 1 2 2 2 0 Elicitor peptide 1-7 Angiomotin_C PF12240.8 PVD19065.1 - 4.2e-23 82.0 43.4 1e-22 80.7 19.0 2.9 1 1 2 3 3 3 2 Angiomotin C terminal OEP PF02321.18 PVD19065.1 - 0.002 17.9 4.2 0.002 17.9 4.2 4.0 2 1 2 4 4 4 1 Outer membrane efflux protein PLAC9 PF15205.6 PVD19065.1 - 0.72 10.3 3.8 2.4 8.6 0.5 3.0 2 0 0 2 2 2 0 Placenta-specific protein 9 TPR_7 PF13176.6 PVD19066.1 - 0.69 10.1 3.1 7.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19066.1 - 0.7 10.2 4.0 24 5.5 0.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat JmjC PF02373.22 PVD19069.1 - 5.4e-29 100.9 0.6 1.3e-28 99.7 0.6 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase TPR_1 PF00515.28 PVD19069.1 - 2.8e-16 58.6 3.7 1.1e-05 25.0 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD19069.1 - 3.7e-12 45.7 1.6 0.0028 17.9 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19069.1 - 1.2e-09 37.5 0.5 0.32 11.2 0.0 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19069.1 - 1.6e-09 37.2 1.3 0.081 13.2 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD19069.1 - 9.7e-07 28.4 1.7 0.00036 20.2 0.0 4.0 2 1 2 4 4 4 1 TPR repeat TPR_19 PF14559.6 PVD19069.1 - 5.7e-05 23.6 0.4 0.62 10.6 1.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD19069.1 - 0.00011 22.4 2.0 0.12 12.7 0.0 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD19069.1 - 0.00012 22.1 0.2 0.013 15.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD19069.1 - 0.00016 21.5 1.5 5.1 7.4 0.0 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD19069.1 - 0.00024 21.7 0.1 1.4 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19069.1 - 0.0082 16.7 0.1 17 6.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD19069.1 - 0.014 15.6 2.2 0.088 13.0 0.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Elf1 PF05129.13 PVD19069.1 - 0.016 15.2 0.9 0.047 13.7 0.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like I-set PF07679.16 PVD19070.1 - 1.2e-06 28.4 0.4 0.018 15.1 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD19070.1 - 1.3e-06 28.4 0.6 0.041 14.1 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 PVD19070.1 - 4.2e-06 27.3 0.7 0.065 13.8 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD19070.1 - 0.00065 19.8 0.0 0.24 11.6 0.0 2.9 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19070.1 - 0.0044 17.3 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD19070.1 - 0.01 15.4 0.0 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain TrwB_AAD_bind PF10412.9 PVD19070.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TSP_1 PF00090.19 PVD19070.1 - 0.1 12.8 4.5 0.2 11.9 2.2 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain GTP_EFTU PF00009.27 PVD19071.1 - 6.2e-61 205.3 0.0 1.2e-60 204.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PVD19071.1 - 4.7e-36 123.2 0.2 1.2e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 PVD19071.1 - 4.5e-28 97.2 0.0 9.5e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PVD19071.1 - 1.2e-23 82.9 0.0 2.8e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PVD19071.1 - 4e-16 59.2 0.3 1.3e-15 57.5 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PA PF02225.22 PVD19071.1 - 2.6e-07 30.5 0.0 6.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PA domain RF3_C PF16658.5 PVD19071.1 - 4.7e-06 26.5 0.0 1.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 PVD19071.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.13 PVD19071.1 - 0.0065 16.5 0.0 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Putative phosphatase (DUF442) AIG1 PF04548.16 PVD19071.1 - 0.027 13.8 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.5 PVD19071.1 - 0.093 13.2 0.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Ras PF00071.22 PVD19072.1 - 2.3e-49 167.1 0.2 2.8e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD19072.1 - 3.4e-25 88.6 0.1 5.8e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD19072.1 - 6e-10 38.8 0.2 7.1e-10 38.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD19072.1 - 7.9e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4524 PF15025.6 PVD19073.1 - 2.9e-40 137.4 0.1 1e-39 135.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.6 PVD19073.1 - 2.5e-23 82.0 0.0 4e-22 78.1 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) Ig_3 PF13927.6 PVD19074.1 - 7e-06 26.6 0.7 0.088 13.4 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19074.1 - 0.0052 16.9 0.2 2.8 8.2 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 PVD19074.1 - 0.025 14.6 0.3 0.17 12.0 0.0 2.3 2 1 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.25 PVD19074.1 - 0.071 13.3 0.8 4.8 7.4 0.2 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 PVD19074.1 - 0.12 12.7 2.9 0.48 10.8 0.0 2.9 3 1 0 3 3 3 0 Immunoglobulin domain SMC_N PF02463.19 PVD19075.1 - 1.4e-72 243.7 33.6 1.7e-70 236.9 33.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD19075.1 - 1.2e-13 51.6 0.1 8.3e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PVD19075.1 - 1.2e-06 29.2 27.2 1.2e-06 29.2 27.2 6.1 1 1 3 4 4 1 1 AAA domain AAA_29 PF13555.6 PVD19075.1 - 3.8e-05 23.3 0.0 8.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 PVD19075.1 - 0.00024 18.8 43.3 0.00024 18.8 43.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) ABC_tran PF00005.27 PVD19075.1 - 0.0042 17.6 0.2 0.0042 17.6 0.2 6.4 2 1 0 3 3 2 1 ABC transporter Tropomyosin_1 PF12718.7 PVD19075.1 - 0.0057 16.8 21.2 0.0057 16.8 21.2 7.0 2 2 4 6 6 4 3 Tropomyosin like Laminin_II PF06009.12 PVD19075.1 - 0.011 15.7 10.8 0.011 15.7 10.8 7.7 3 2 4 8 8 8 0 Laminin Domain II AAA_22 PF13401.6 PVD19075.1 - 0.7 10.2 5.5 2.6 8.3 0.0 4.0 4 1 0 4 4 4 0 AAA domain AAA_15 PF13175.6 PVD19075.1 - 1.5 8.4 75.3 0.035 13.8 42.6 3.9 1 1 1 2 2 1 0 AAA ATPase domain Vac_Fusion PF02346.16 PVD19075.1 - 1.6 8.4 11.6 8.6 6.1 0.1 5.8 4 1 1 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 Metal_resist PF13801.6 PVD19075.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.8 5 0 0 5 5 5 0 Heavy-metal resistance GDP_Man_Dehyd PF16363.5 PVD19076.1 - 7.4e-57 193.2 0.0 1.6e-56 192.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD19076.1 - 1.7e-50 171.7 0.0 2.1e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD19076.1 - 1.7e-10 40.3 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PVD19076.1 - 7.6e-10 38.4 0.1 2.5e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PVD19076.1 - 2e-08 33.7 0.0 3.5e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PVD19076.1 - 1.5e-07 30.9 0.6 0.0078 15.4 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 PVD19076.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Cupin_8 PF13621.6 PVD19076.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupin-like domain FUN14 PF04930.15 PVD19077.1 - 3.1e-24 85.2 1.8 4.1e-24 84.8 1.8 1.2 1 0 0 1 1 1 1 FUN14 family DUF3852 PF12963.7 PVD19077.1 - 0.046 14.1 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Pkinase PF00069.25 PVD19078.1 - 2.6e-40 138.5 0.0 4.7e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD19078.1 - 6.6e-38 130.5 0.0 1.3e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Death_2 PF14786.6 PVD19078.1 - 9e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Tube Death domain Death PF00531.22 PVD19078.1 - 0.0004 20.5 0.4 0.0018 18.4 0.4 2.1 1 1 0 1 1 1 1 Death domain Kinase-like PF14531.6 PVD19078.1 - 0.0028 17.0 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SBP56 PF05694.11 PVD19079.1 - 1e-196 654.2 0.0 1.2e-196 654.0 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 PVD19079.1 - 0.012 14.9 0.0 0.073 12.3 0.0 2.2 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Glyco_transf_22 PF03901.17 PVD19080.1 - 3.2e-73 247.4 29.3 6.4e-64 216.7 26.3 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Arm PF00514.23 PVD19081.1 - 1.4e-45 151.9 5.9 5e-12 45.4 0.0 5.5 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 PVD19081.1 - 2.7e-28 97.3 5.2 6.1e-25 86.5 3.8 2.6 2 0 0 2 2 2 2 Atypical Arm repeat IBB PF01749.20 PVD19081.1 - 4.2e-13 49.6 2.2 6.9e-13 48.8 1.1 1.9 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 PVD19081.1 - 9.1e-08 32.4 0.0 0.0009 19.6 0.0 3.3 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 PVD19081.1 - 2.5e-07 31.1 0.0 0.0038 17.7 0.0 3.4 2 1 1 3 3 3 3 HEAT-like repeat HEAT PF02985.22 PVD19081.1 - 5.9e-06 26.1 0.1 0.0053 16.9 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 PVD19081.1 - 0.00017 21.6 0.1 0.38 10.8 0.1 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 PVD19081.1 - 0.00037 20.6 0.3 0.62 10.2 0.0 2.6 2 1 0 2 2 2 2 V-ATPase subunit H Arm_2 PF04826.13 PVD19081.1 - 0.0035 16.8 0.1 2.5 7.5 0.0 3.2 2 1 1 3 3 3 1 Armadillo-like Mo25 PF08569.11 PVD19081.1 - 0.013 14.8 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Mo25-like DUF5564 PF17719.1 PVD19081.1 - 0.041 14.0 0.6 0.087 13.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5564) CTNNBL PF08216.11 PVD19081.1 - 0.065 13.4 0.2 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear NopRA1 PF16201.5 PVD19081.1 - 0.12 11.9 0.0 29 4.2 0.0 3.3 1 1 2 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 PVD19082.1 - 4e-139 463.5 13.9 5e-139 463.2 13.9 1.0 1 0 0 1 1 1 1 Mo25-like FMO-like PF00743.19 PVD19083.1 - 1.2e-97 327.6 0.0 1.6e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD19083.1 - 8.8e-18 64.6 0.2 1e-14 54.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD19083.1 - 3.3e-14 52.8 0.1 8e-12 45.0 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD19083.1 - 1.2e-09 37.8 0.1 7.2e-08 32.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PVD19083.1 - 1.4e-09 38.0 0.0 3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD19083.1 - 1.7e-07 31.1 0.5 0.00017 21.3 0.5 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 PVD19083.1 - 4.8e-07 29.3 0.2 1e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PVD19083.1 - 8e-07 28.5 0.2 1.3e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PVD19083.1 - 8.6e-07 28.6 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PVD19083.1 - 3.3e-06 26.6 0.0 1.7e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 PVD19083.1 - 3.8e-06 26.4 0.1 0.00013 21.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PVD19083.1 - 1.2e-05 24.2 0.1 6.1e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 PVD19083.1 - 6.3e-05 23.5 5.2 0.00074 20.0 0.8 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PVD19083.1 - 0.0033 16.6 0.1 0.0061 15.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 PVD19083.1 - 0.0034 17.4 0.4 0.17 11.9 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 PVD19083.1 - 0.0036 16.4 0.0 0.011 14.8 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PVD19083.1 - 0.0038 16.6 0.2 0.0066 15.8 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 PVD19083.1 - 0.014 15.4 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 PVD19083.1 - 0.046 14.2 0.1 3 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 PVD19083.1 - 0.055 13.0 0.3 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ion_trans PF00520.31 PVD19084.1 - 3.7e-133 442.2 101.7 1.4e-38 132.6 12.3 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 PVD19084.1 - 0.00017 20.4 9.2 0.00017 20.4 9.2 7.7 6 4 3 9 9 9 5 Polycystin cation channel Exo_endo_phos_2 PF14529.6 PVD19086.1 - 1.2e-11 44.5 0.2 1.5e-11 44.1 0.2 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD19086.1 - 0.019 14.5 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Myosin_head PF00063.21 PVD19088.1 - 7.8e-243 807.6 6.7 1.2e-242 807.0 6.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 PVD19088.1 - 9e-64 212.7 6.6 5.1e-32 110.6 0.0 3.5 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.18 PVD19088.1 - 1.5e-13 51.2 0.5 1.7e-05 25.2 0.0 4.4 4 0 0 4 4 4 2 FERM central domain FERM_N PF09379.10 PVD19088.1 - 5.2e-08 32.7 0.6 0.0069 16.3 0.0 3.6 3 0 0 3 3 3 2 FERM N-terminal domain IQ PF00612.27 PVD19088.1 - 8.4e-06 25.1 25.3 0.011 15.5 0.7 5.5 5 0 0 5 5 5 4 IQ calmodulin-binding motif RA PF00788.23 PVD19088.1 - 0.0017 19.0 0.0 0.4 11.4 0.0 3.2 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain AAA_22 PF13401.6 PVD19088.1 - 0.0021 18.3 0.7 0.079 13.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain SH3_1 PF00018.28 PVD19088.1 - 0.0029 17.2 0.2 0.11 12.1 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD19088.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain ABC_tran PF00005.27 PVD19088.1 - 0.18 12.3 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 1 0 ABC transporter DUF5401 PF17380.2 PVD19088.1 - 0.27 9.3 18.5 0.43 8.6 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4446 PF14584.6 PVD19088.1 - 4.4 7.3 5.7 40 4.1 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) MFS_1 PF07690.16 PVD19089.1 - 5.5e-23 81.5 67.7 1.3e-19 70.4 42.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 PVD19089.1 - 1.3 7.3 9.2 0.027 12.9 0.6 2.2 2 2 0 2 2 2 0 Transmembrane secretion effector Argos PF11581.8 PVD19090.1 - 0.17 11.9 6.1 1.2 9.1 0.4 2.8 2 1 1 3 3 3 0 Antagonist of EGFR signalling, Argos DUF1647 PF07801.11 PVD19091.1 - 0.00031 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Peptidase_M28 PF04389.17 PVD19091.1 - 0.017 14.8 1.7 0.03 14.0 0.2 2.1 2 1 0 2 2 2 0 Peptidase family M28 MORN PF02493.20 PVD19092.1 - 1.8e-27 93.5 30.7 2.6e-07 30.2 0.6 6.6 6 0 0 6 6 6 6 MORN repeat Ank_2 PF12796.7 PVD19092.1 - 5.5e-20 71.7 0.3 1.9e-07 31.6 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD19092.1 - 8e-14 51.4 19.1 2.4e-05 24.6 0.4 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 PVD19092.1 - 2.7e-12 46.9 7.5 0.0045 17.5 0.1 6.9 4 3 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD19092.1 - 2.4e-10 39.7 10.4 0.0037 17.6 0.2 6.8 7 0 0 7 7 7 2 Ankyrin repeat zf-MYND PF01753.18 PVD19092.1 - 1.1e-08 35.1 11.8 2.2e-08 34.0 11.8 1.6 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 PVD19092.1 - 1.7e-07 31.3 7.8 0.047 14.0 0.2 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DUF2256 PF10013.9 PVD19092.1 - 2.2 8.5 6.7 4.3 7.5 6.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) EMP70 PF02990.16 PVD19093.1 - 3.5e-41 141.5 1.0 4e-41 141.3 1.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 PRP21_like_P PF12230.8 PVD19095.1 - 5e-44 150.8 24.1 2.3e-27 96.3 4.1 2.7 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 PVD19095.1 - 1.4e-42 143.5 7.4 4.6e-22 77.7 1.1 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 PVD19095.1 - 9.5e-13 47.7 0.0 2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PVD19095.1 - 0.003 18.0 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain COesterase PF00135.28 PVD19096.1 - 1.6e-138 462.8 0.0 1.9e-138 462.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD19096.1 - 0.00055 19.9 0.1 0.0022 17.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold AKAP28 PF14469.6 PVD19098.1 - 1.2e-39 134.8 2.2 2e-39 134.1 2.2 1.3 1 0 0 1 1 1 1 28 kDa A-kinase anchor TPR_2 PF07719.17 PVD19099.1 - 6.7e-22 75.8 26.9 0.0011 18.9 0.0 9.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19099.1 - 2.5e-20 71.3 18.0 7.9e-06 25.5 0.9 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19099.1 - 2.5e-18 64.7 9.9 0.0044 17.1 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD19099.1 - 3.6e-18 65.6 23.5 2.2e-13 50.2 5.5 5.9 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PVD19099.1 - 3.1e-16 59.4 17.4 6.7e-08 32.7 1.8 6.3 6 2 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD19099.1 - 1.7e-14 52.7 16.2 0.0037 17.2 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD19099.1 - 9.9e-12 44.3 13.4 0.0006 19.6 0.4 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD19099.1 - 1e-09 38.4 21.6 2.5 9.1 0.0 8.6 5 4 4 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD19099.1 - 2.4e-08 34.3 10.4 0.0026 18.2 0.2 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD19099.1 - 8e-06 25.9 10.2 14 6.3 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD19099.1 - 4.1e-05 23.1 2.7 0.00099 18.6 0.1 2.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 PVD19099.1 - 6.9e-05 22.4 1.3 0.027 14.2 0.4 4.3 5 1 1 6 6 6 1 TPR repeat TPR_16 PF13432.6 PVD19099.1 - 0.00045 20.8 19.9 0.33 11.6 0.9 6.1 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19099.1 - 0.00048 20.6 19.3 30 5.5 0.1 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PVD19099.1 - 0.012 15.3 0.0 1.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 PVD19099.1 - 0.013 15.6 9.6 21 5.3 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 PVD19099.1 - 0.034 14.1 8.0 24 5.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC8 PF04049.13 PVD19099.1 - 0.039 14.0 0.7 1.9 8.6 0.2 2.6 1 1 1 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Foie-gras_1 PF11817.8 PVD19099.1 - 0.12 11.9 2.1 0.12 12.0 0.3 1.9 2 0 0 2 2 2 0 Foie gras liver health family 1 Fis1_TPR_C PF14853.6 PVD19099.1 - 0.15 12.1 5.6 30 4.8 0.1 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD19099.1 - 0.19 11.8 4.8 1.8 8.6 0.1 3.6 4 0 0 4 4 4 0 Putative TPR-like repeat TPR_4 PF07721.14 PVD19099.1 - 0.31 11.8 1.7 13 6.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 PVD19100.1 - 1.5e-71 242.0 0.2 2e-71 241.7 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD19100.1 - 3.5e-14 52.8 1.1 6.4e-14 51.9 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD19100.1 - 4.3e-10 39.7 0.1 4.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD19100.1 - 1.4e-07 31.0 1.4 2.2e-07 30.3 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PVD19100.1 - 1.8e-07 30.8 0.1 2.8e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PVD19100.1 - 1e-06 28.2 0.3 1.7e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 PVD19100.1 - 2.5e-06 27.0 0.3 4.1e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PVD19100.1 - 4e-05 22.5 0.0 7.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PVD19100.1 - 7.3e-05 23.2 0.6 0.00023 21.7 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD19100.1 - 7.8e-05 22.0 0.3 0.00025 20.4 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PVD19100.1 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PVD19100.1 - 0.006 15.7 0.2 0.0094 15.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PVD19100.1 - 0.0075 15.6 0.5 0.013 14.8 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 PVD19100.1 - 0.021 14.1 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PVD19100.1 - 0.026 14.5 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 PVD19100.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 PVD19100.1 - 0.15 11.9 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 PVD19101.1 - 8.6e-50 170.3 0.0 1.8e-49 169.3 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase LRR_8 PF13855.6 PVD19102.1 - 2.1e-76 251.6 55.8 4.8e-10 39.1 0.1 12.2 9 3 2 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 PVD19102.1 - 8.1e-57 188.2 65.2 3.4e-05 24.1 0.3 17.3 5 5 14 21 21 21 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD19102.1 - 6e-25 83.9 39.7 3.2 8.6 0.1 22.6 24 3 1 25 25 25 5 Leucine Rich Repeat LRR_9 PF14580.6 PVD19102.1 - 1.4e-14 54.0 32.9 0.022 14.2 0.3 8.5 2 1 6 9 9 9 9 Leucine-rich repeat LRR_6 PF13516.6 PVD19102.1 - 6.8e-11 41.3 66.0 6.4 7.1 0.0 20.0 23 0 0 23 23 23 7 Leucine Rich repeat RsmF_methylt_CI PF17126.5 PVD19102.1 - 0.0069 16.4 2.8 11 6.1 0.0 6.1 7 0 0 7 7 7 1 RsmF rRNA methyltransferase first C-terminal domain Aldo_ket_red PF00248.21 PVD19103.1 - 1.2e-40 139.6 0.0 1.6e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Viral_P18 PF04521.13 PVD19103.1 - 0.031 14.0 0.1 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Acetyltransf_1 PF00583.25 PVD19104.1 - 3.6e-09 36.9 0.0 4.3e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD19104.1 - 1.1e-06 28.9 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD19104.1 - 5.7e-05 23.1 0.0 6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PVD19104.1 - 0.022 14.9 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ank_2 PF12796.7 PVD19105.1 - 1.2e-40 138.0 3.2 3.5e-15 56.4 0.0 3.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD19105.1 - 3.7e-38 129.4 10.6 9.2e-13 48.4 0.2 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD19105.1 - 2e-31 107.6 3.2 3.5e-08 33.6 0.0 5.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD19105.1 - 1e-23 80.8 3.4 9.8e-05 22.5 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 PVD19105.1 - 3.8e-22 77.7 6.2 9.4e-06 25.9 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Spc29 PF17082.5 PVD19105.1 - 0.0011 18.8 6.6 0.0016 18.4 6.6 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF724 PF05266.14 PVD19105.1 - 0.064 13.1 4.8 0.08 12.8 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) BST2 PF16716.5 PVD19105.1 - 0.23 12.1 2.8 0.52 10.9 2.8 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 COG2 PF06148.11 PVD19105.1 - 0.62 10.2 4.4 8.5 6.5 3.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pox_A_type_inc PF04508.12 PVD19105.1 - 3.6 7.6 19.1 3.4 7.7 1.4 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TolA_bind_tri PF16331.5 PVD19105.1 - 9 6.5 12.2 13 6.0 0.5 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation Sipho_tail PF05709.11 PVD19106.1 - 0.19 11.1 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein Dzip-like_N PF13815.6 PVD19107.1 - 2.6e-38 130.6 4.4 2.6e-38 130.6 4.4 3.4 2 1 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal FAM76 PF16046.5 PVD19107.1 - 0.0012 18.3 4.6 0.0012 18.3 4.6 2.7 2 1 2 4 4 4 1 FAM76 protein zf-Di19 PF05605.12 PVD19107.1 - 0.0087 16.3 0.1 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 PVD19107.1 - 0.049 14.5 0.3 0.14 13.0 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD19107.1 - 0.063 13.8 0.3 0.17 12.4 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DnaJ PF00226.31 PVD19108.1 - 1.6e-22 79.4 1.6 1.6e-22 79.4 1.6 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 PVD19108.1 - 6.9e-22 75.8 4.1 4e-06 26.5 0.1 7.7 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19108.1 - 5e-17 60.9 6.9 1.4e-06 27.9 0.1 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD19108.1 - 7.1e-16 57.6 0.8 0.0013 19.4 0.2 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19108.1 - 4.4e-14 51.4 4.9 0.0066 16.6 0.0 6.6 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD19108.1 - 1.1e-13 51.5 1.2 1e-08 35.7 0.2 3.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD19108.1 - 9.3e-12 44.4 5.2 6.5e-06 25.7 0.1 6.1 5 2 2 7 7 6 2 TPR repeat TPR_17 PF13431.6 PVD19108.1 - 5.3e-11 42.1 5.6 0.047 14.1 0.0 7.8 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD19108.1 - 1.7e-10 41.2 0.2 4.3e-05 23.9 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD19108.1 - 1.9e-09 37.5 2.4 0.00075 19.6 0.0 4.9 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD19108.1 - 8e-09 35.7 2.8 0.046 14.0 0.0 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD19108.1 - 3.8e-07 30.2 0.8 0.012 15.8 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PVD19108.1 - 1.2e-05 24.6 5.7 0.27 10.4 0.1 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19108.1 - 1.3e-05 25.5 6.4 1.2 9.9 0.1 6.4 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 PVD19108.1 - 1.6e-05 25.1 5.5 1.2 9.6 0.0 5.3 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD19108.1 - 7.3e-05 22.5 2.2 0.11 12.4 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 PVD19108.1 - 0.00014 21.6 1.2 0.002 17.9 0.0 2.9 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 PVD19108.1 - 0.0065 16.9 1.0 4 7.9 0.1 3.3 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 PVD19108.1 - 0.0083 16.1 0.1 1.7 8.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PVD19108.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.12 PVD19108.1 - 0.024 14.7 0.3 1.9 8.5 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF627) ANAPC5 PF12862.7 PVD19108.1 - 0.032 14.3 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.6 PVD19108.1 - 0.089 12.9 4.0 29 4.8 0.1 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 PVD19108.1 - 0.11 13.2 0.0 14 6.6 0.0 3.5 5 0 0 5 5 2 0 Tetratricopeptide repeat DUF262 PF03235.14 PVD19108.1 - 0.18 12.0 4.6 0.085 13.0 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 MAS20 PF02064.15 PVD19108.1 - 5.5 7.1 10.8 2.3 8.3 0.1 3.5 2 2 2 4 4 4 0 MAS20 protein import receptor DP PF08781.10 PVD19109.1 - 9.5e-63 210.2 1.1 2e-62 209.2 1.1 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 PVD19109.1 - 1.5e-25 89.0 0.0 4.2e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DAGAT PF03982.13 PVD19110.1 - 1.2e-100 336.3 0.0 1.6e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 PVD19111.1 - 7.5e-72 241.7 0.0 9e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2870 PF11069.8 PVD19112.1 - 0.0055 17.1 1.6 0.0072 16.7 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2870) NIR_SIR_ferr PF03460.17 PVD19112.1 - 0.096 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain WW PF00397.26 PVD19113.1 - 3.5e-10 39.8 9.3 2e-09 37.4 0.3 3.3 3 0 0 3 3 3 2 WW domain TFIIA PF03153.13 PVD19113.1 - 0.2 11.6 9.1 0.25 11.3 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ig_3 PF13927.6 PVD19114.1 - 6.7e-09 36.2 0.8 0.00066 20.2 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD19114.1 - 1.2e-06 28.6 0.3 0.0014 18.7 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19114.1 - 4.5e-05 23.4 0.1 0.0036 17.4 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 PVD19114.1 - 0.0006 20.0 0.2 1.1 9.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin V-set domain Hydrolase_4 PF12146.8 PVD19114.1 - 0.053 12.8 0.2 0.09 12.0 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TIR_2 PF13676.6 PVD19115.1 - 0.066 13.8 0.1 0.14 12.8 0.1 1.6 1 0 0 1 1 1 0 TIR domain NLRC4_HD PF17889.1 PVD19115.1 - 0.19 12.0 1.3 0.82 10.0 0.1 2.5 3 0 0 3 3 3 0 NLRC4 helical domain Sulfotransfer_2 PF03567.14 PVD19116.1 - 1.4e-31 110.4 0.3 7.5e-28 98.1 0.1 2.4 2 0 0 2 2 2 2 Sulfotransferase family 7tm_1 PF00001.21 PVD19117.1 - 2e-15 56.8 10.0 3.8e-15 55.9 10.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19117.1 - 1.2e-05 25.1 4.9 1.2e-05 25.1 4.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD19117.1 - 0.00075 18.9 6.8 0.0014 18.0 6.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 PVD19117.1 - 0.59 10.1 8.3 0.053 13.5 1.9 2.5 2 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa MFS_1 PF07690.16 PVD19118.1 - 1.7e-12 47.0 6.7 4.5e-12 45.6 6.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CaKB PF03185.15 PVD19118.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit MFS_1 PF07690.16 PVD19119.1 - 8.4e-17 61.1 0.5 1.8e-13 50.2 0.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily CaKB PF03185.15 PVD19119.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit MFS_1 PF07690.16 PVD19120.1 - 2.8e-18 66.0 14.8 3.3e-17 62.4 9.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 PVD19121.1 - 0.014 14.3 6.1 0.016 14.1 6.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SCAN PF02023.17 PVD19123.1 - 5.8e-13 48.5 0.0 1.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 PVD19123.1 - 1.7e-06 27.8 4.4 2.8e-06 27.1 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 PVD19123.1 - 0.00034 20.8 0.0 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 PVD19123.1 - 0.00047 19.9 5.4 0.00052 19.8 2.6 2.1 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 PVD19123.1 - 0.0009 19.8 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PVD19123.1 - 0.0011 19.5 0.1 0.0033 18.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ROS_MUCR PF05443.11 PVD19123.1 - 0.19 11.8 0.9 15 5.7 0.1 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein VWD PF00094.25 PVD19125.1 - 9.3e-13 48.7 2.0 1.2e-05 25.7 0.8 2.9 2 1 0 2 2 2 2 von Willebrand factor type D domain EGF_2 PF07974.13 PVD19125.1 - 0.0071 16.7 36.6 0.022 15.1 10.4 4.0 3 0 0 3 3 3 2 EGF-like domain DUF5615 PF18480.1 PVD19125.1 - 0.033 14.0 0.2 20 5.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5615) zf-Di19 PF05605.12 PVD19125.1 - 0.99 9.8 6.6 40 4.6 0.1 4.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C6H2 PF15801.5 PVD19125.1 - 3.7 7.9 7.1 9.6 6.6 0.2 3.4 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding LRR_4 PF12799.7 PVD19128.1 - 8.1e-11 42.0 8.7 4e-07 30.3 4.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) CUB PF00431.20 PVD19128.1 - 1.6e-10 41.3 0.0 2.9e-05 24.3 0.0 2.7 3 0 0 3 3 3 2 CUB domain LRR_8 PF13855.6 PVD19128.1 - 9e-10 38.2 13.5 6.1e-07 29.1 6.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat Lectin_C PF00059.21 PVD19128.1 - 3.5e-06 27.7 0.0 8.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD19128.1 - 0.015 15.5 2.0 0.015 15.5 2.0 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A NDC10_II PF16787.5 PVD19128.1 - 0.025 13.7 0.3 0.042 12.9 0.3 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CUB_2 PF02408.20 PVD19128.1 - 0.06 13.1 0.8 0.35 10.6 0.0 2.5 3 0 0 3 3 3 0 CUB-like domain LRR_1 PF00560.33 PVD19128.1 - 3.5 8.5 11.7 20 6.2 0.3 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat Collagen PF01391.18 PVD19129.1 - 1.6e-207 671.6 699.1 4.5e-09 35.9 22.1 29.8 7 7 21 28 28 28 28 Collagen triple helix repeat (20 copies) C4 PF01413.19 PVD19129.1 - 2e-77 256.7 0.5 1.1e-38 132.0 0.1 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 PVD19130.1 - 2.1e-218 706.4 712.0 6.2e-10 38.7 19.7 28.8 5 4 21 26 26 26 26 Collagen triple helix repeat (20 copies) C4 PF01413.19 PVD19130.1 - 1.3e-82 273.4 1.4 2.8e-44 150.0 0.1 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen CEP19 PF14933.6 PVD19131.1 - 1.6e-42 145.6 0.3 1.9e-42 145.4 0.3 1.1 1 0 0 1 1 1 1 CEP19-like protein STAG PF08514.11 PVD19132.1 - 7.8e-39 132.1 3.8 2.6e-38 130.4 0.1 3.2 3 0 0 3 3 3 1 STAG domain Glyco_hydro_31 PF01055.26 PVD19133.1 - 1.9e-123 412.9 4.7 3.1e-123 412.2 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PVD19133.1 - 4.1e-23 81.8 0.6 7.2e-23 81.0 0.6 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 PVD19133.1 - 1.3e-05 25.4 0.9 4.5e-05 23.7 0.9 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Amidohydro_1 PF01979.20 PVD19134.1 - 4.2e-56 190.7 0.0 6.4e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ta0938 PF11494.8 PVD19134.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Ta0938 Amidohydro_3 PF07969.11 PVD19134.1 - 0.14 11.6 0.0 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Amidohydrolase family LRR_4 PF12799.7 PVD19135.1 - 9.8e-13 48.1 17.6 4e-05 23.9 0.3 4.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD19135.1 - 1.5e-09 37.5 18.3 0.0013 18.4 0.4 4.5 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PVD19135.1 - 2.4e-05 24.0 9.5 3.1 8.1 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 PVD19135.1 - 0.0061 16.9 13.8 14 6.7 0.0 6.7 6 1 0 6 6 6 1 Leucine Rich Repeat Atg31 PF09795.9 PVD19135.1 - 0.04 13.9 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Autophagy-related protein 31 LRR_9 PF14580.6 PVD19135.1 - 0.059 12.9 8.0 1.8 8.0 2.8 3.4 3 1 1 4 4 4 0 Leucine-rich repeat EHD_N PF16880.5 PVD19136.1 - 0.084 12.8 0.6 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 N-terminal EH-domain containing protein ATG16 PF08614.11 PVD19136.1 - 0.22 11.7 3.6 0.13 12.5 1.1 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ATG16 PF08614.11 PVD19138.1 - 0.044 14.0 0.5 0.071 13.3 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) EHD_N PF16880.5 PVD19138.1 - 0.05 13.5 0.4 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 N-terminal EH-domain containing protein MFS_1 PF07690.16 PVD19139.1 - 2.2e-18 66.3 46.2 4e-09 35.9 18.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2368 PF10166.9 PVD19139.1 - 0.078 12.6 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) MFS_2 PF13347.6 PVD19139.1 - 2.6 6.5 32.8 0.014 14.0 9.9 2.9 3 0 0 3 3 3 0 MFS/sugar transport protein MFS_3 PF05977.13 PVD19139.1 - 3.8 5.8 10.9 0.43 8.9 1.9 2.9 2 1 1 3 3 3 0 Transmembrane secretion effector Cyclin_N PF00134.23 PVD19140.1 - 5.2e-18 65.0 4.8 1.8e-14 53.5 1.9 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 PVD19140.1 - 1e-05 25.8 0.1 3.8e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 PVD19140.1 - 0.0089 16.1 0.3 0.16 12.1 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 PVD19140.1 - 0.027 14.6 2.6 0.087 12.9 0.2 2.8 2 1 1 3 3 3 0 Cyclin, C-terminal domain DUF2776 PF10951.8 PVD19140.1 - 0.44 9.8 2.2 7.8 5.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) TipAS PF07739.13 PVD19140.1 - 0.72 10.4 3.6 5.5 7.6 0.9 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain ADP_ribosyl_GH PF03747.14 PVD19142.1 - 3e-23 83.0 0.0 4.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pea-VEAacid PF08111.11 PVD19142.1 - 0.073 13.4 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Pea-VEAacid family SelR PF01641.18 PVD19143.1 - 1.7e-49 166.9 0.3 2.3e-49 166.5 0.3 1.2 1 0 0 1 1 1 1 SelR domain MTCP1 PF08991.10 PVD19144.1 - 0.029 14.6 1.4 0.091 13.0 1.4 1.9 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type zf-RING_2 PF13639.6 PVD19145.1 - 1.9e-09 37.7 6.9 1.9e-09 37.7 6.9 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 PVD19145.1 - 8.4e-09 35.2 4.5 8.4e-09 35.2 4.5 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD19145.1 - 1e-08 35.0 7.0 2.6e-08 33.7 6.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD19145.1 - 1.9e-07 30.8 5.4 1.9e-07 30.8 5.4 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD19145.1 - 4.9e-07 29.5 5.5 4.9e-07 29.5 5.5 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD19145.1 - 2.3e-06 27.4 6.5 2.3e-06 27.4 6.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD19145.1 - 7.6e-06 26.0 7.3 7.6e-06 26.0 7.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD19145.1 - 5.8e-05 23.0 5.3 5.8e-05 23.0 5.3 3.0 4 0 0 4 4 4 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD19145.1 - 0.0033 17.4 5.8 0.0033 17.4 5.8 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PVD19145.1 - 0.031 14.6 4.5 0.031 14.6 4.5 2.7 3 1 0 3 3 3 0 RING-H2 zinc finger domain Ig_Tie2_1 PF10430.9 PVD19145.1 - 0.05 14.0 0.3 3 8.3 0.1 2.4 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Rad50_zn_hook PF04423.14 PVD19145.1 - 1 9.2 5.4 0.96 9.3 1.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PVD19145.1 - 8.1 6.3 13.5 0.18 11.6 4.6 2.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain 5_nucleotid PF05761.14 PVD19146.1 - 5.6e-150 500.2 0.5 7.3e-150 499.9 0.5 1.1 1 0 0 1 1 1 1 5' nucleotidase family FAD_binding_7 PF03441.14 PVD19146.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Autophagy_act_C PF03987.15 PVD19147.1 - 1e-21 77.2 0.7 2.9e-21 75.8 0.7 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_N PF03986.13 PVD19147.1 - 7.1e-10 39.0 2.3 1.4e-09 38.0 2.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain SDA1 PF05285.12 PVD19147.1 - 1.2 8.5 6.6 1.6 8.1 6.6 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 PVD19147.1 - 1.7 8.7 6.9 2.2 8.3 6.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Scramblase PF03803.15 PVD19148.1 - 5e-87 290.8 0.2 2.1e-71 239.7 0.1 2.0 2 0 0 2 2 2 2 Scramblase DUF2375 PF09558.10 PVD19148.1 - 0.12 12.4 0.4 8.5 6.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2375) Scramblase PF03803.15 PVD19149.1 - 1.7e-83 279.3 0.0 2e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Scramblase BHD_3 PF10405.9 PVD19149.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 Patatin PF01734.22 PVD19150.1 - 9.1e-16 58.7 0.6 3.9e-15 56.6 0.6 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Pex14_N PF04695.13 PVD19150.1 - 0.0017 19.0 0.1 0.0029 18.3 0.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Colicin_V PF02674.16 PVD19150.1 - 0.13 12.2 0.3 0.21 11.5 0.3 1.2 1 0 0 1 1 1 0 Colicin V production protein DNA_ligase_aden PF01653.18 PVD19151.1 - 0.0044 16.2 0.1 0.0095 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain Snapin_Pallidin PF14712.6 PVD19152.1 - 0.0062 16.9 0.6 0.43 11.0 0.0 2.2 2 0 0 2 2 2 2 Snapin/Pallidin RNase_P_p30 PF01876.16 PVD19153.1 - 0.0057 16.1 0.3 0.68 9.4 0.1 2.3 2 0 0 2 2 2 2 RNase P subunit p30 DUF4110 PF13422.6 PVD19153.1 - 0.08 13.0 0.2 0.08 13.0 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4110) Taxilin PF09728.9 PVD19153.1 - 1.8 7.7 34.4 0.63 9.2 13.6 2.9 1 1 1 2 2 2 0 Myosin-like coiled-coil protein LIAS_N PF16881.5 PVD19153.1 - 2 8.8 5.7 0.29 11.6 0.2 2.4 3 0 0 3 3 3 0 N-terminal domain of lipoyl synthase of Radical_SAM family GvpG PF05120.12 PVD19153.1 - 6.6 6.8 6.8 4.8 7.3 2.8 3.0 3 1 0 3 3 3 0 Gas vesicle protein G SLED PF12140.8 PVD19153.1 - 8.8 6.9 6.6 2.6 8.6 0.2 3.2 2 2 1 3 3 3 0 SLED domain HALZ PF02183.18 PVD19153.1 - 9.6 6.5 9.6 2 8.7 0.2 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper AAA_6 PF12774.7 PVD19154.1 - 1.3e-158 527.2 0.3 5.5e-157 521.9 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD19154.1 - 2.3e-135 451.8 17.7 2.3e-135 451.8 17.7 6.1 7 1 1 8 8 8 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD19154.1 - 2.7e-104 348.7 1.7 2.8e-103 345.3 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain DHC_N1 PF08385.12 PVD19154.1 - 1.7e-102 343.9 0.0 1.7e-102 343.9 0.0 4.6 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 PVD19154.1 - 3.1e-92 307.7 1.0 3.1e-92 307.7 1.0 4.0 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 PVD19154.1 - 1.5e-87 293.2 2.9 3e-84 282.4 0.4 3.9 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD19154.1 - 2.3e-73 245.6 1.7 2.9e-70 235.5 0.1 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD19154.1 - 3.3e-61 205.9 0.2 1.1e-60 204.2 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD19154.1 - 7.3e-61 206.1 9.5 1.6e-60 204.9 9.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD19154.1 - 3.6e-47 159.4 0.5 5.4e-43 145.9 0.0 4.4 4 0 0 4 4 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD19154.1 - 1.5e-31 109.1 0.5 7.4e-31 106.9 0.5 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD19154.1 - 1.2e-30 106.3 0.0 1.1e-15 57.9 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD19154.1 - 4.7e-19 68.5 0.6 4.7e-19 68.5 0.6 3.5 3 0 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 PVD19154.1 - 2.2e-09 37.8 1.5 0.004 17.6 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD19154.1 - 1e-05 25.9 0.4 0.0065 16.8 0.0 4.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PVD19154.1 - 1.8e-05 25.3 0.0 0.25 11.9 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 PVD19154.1 - 0.00091 19.7 4.7 0.27 11.6 0.0 5.6 6 1 1 7 7 6 1 AAA ATPase domain AAA_33 PF13671.6 PVD19154.1 - 0.003 17.7 0.1 0.65 10.1 0.0 3.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 PVD19154.1 - 0.0056 16.4 0.0 0.058 13.1 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PVD19154.1 - 0.039 14.1 0.0 4.9 7.3 0.0 3.2 2 0 0 2 2 2 0 Sigma-54 interaction domain CbiA PF01656.23 PVD19154.1 - 0.044 13.8 0.2 0.6 10.2 0.0 3.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 PVD19154.1 - 0.046 13.4 0.3 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD19154.1 - 0.088 12.7 1.6 0.93 9.4 0.0 3.3 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PVD19154.1 - 0.12 12.4 0.2 5 7.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain Guanylate_kin PF00625.21 PVD19154.1 - 0.8 9.4 6.6 8.9 5.9 0.9 3.3 3 0 0 3 3 3 0 Guanylate kinase AAA_24 PF13479.6 PVD19154.1 - 1.4 8.6 5.8 4.1 7.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain DUF3752 PF12572.8 PVD19155.1 - 1.9e-17 64.2 21.2 1.9e-17 64.2 21.2 12.9 9 3 5 14 14 14 1 Protein of unknown function (DUF3752) AAA_6 PF12774.7 PVD19156.1 - 8.1e-155 514.7 0.5 1.1e-153 510.9 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PVD19156.1 - 5.4e-116 388.5 8.2 5.4e-116 388.5 8.2 5.9 4 2 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 PVD19156.1 - 6e-109 363.3 3.7 6.5e-108 360.0 0.2 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 PVD19156.1 - 6.5e-108 361.4 20.8 6.5e-108 361.4 20.8 5.0 5 2 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD19156.1 - 4.5e-101 338.1 0.0 4.5e-101 338.1 0.0 4.5 5 1 1 6 6 6 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD19156.1 - 2.9e-85 284.9 0.3 2.9e-85 284.9 0.3 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 PVD19156.1 - 1.2e-60 205.4 10.3 3.5e-60 203.8 10.3 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 PVD19156.1 - 3.1e-60 202.8 3.1 2.3e-58 196.7 0.1 3.6 3 1 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD19156.1 - 5e-52 176.0 0.1 1.5e-51 174.5 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD19156.1 - 8.3e-28 97.1 0.0 2.7e-13 50.1 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PVD19156.1 - 9.2e-28 96.9 0.3 3.8e-27 94.9 0.3 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD19156.1 - 1.2e-25 89.9 0.5 4.8e-23 81.5 0.1 3.9 2 1 1 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 PVD19156.1 - 1.2e-23 83.2 5.6 2.2e-21 75.9 0.4 4.0 3 0 0 3 3 3 1 AAA+ lid domain AAA PF00004.29 PVD19156.1 - 7.2e-10 39.4 0.2 0.0012 19.2 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PVD19156.1 - 7.2e-07 29.8 0.0 0.0014 19.2 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD19156.1 - 3.6e-05 24.1 0.5 0.059 13.7 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 PVD19156.1 - 0.0014 19.0 1.0 0.15 12.4 0.0 4.0 4 0 0 4 4 3 1 AAA ATPase domain T2SSE PF00437.20 PVD19156.1 - 0.013 14.5 0.2 0.14 11.2 0.1 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 PVD19156.1 - 0.016 15.4 0.0 3.5 7.8 0.0 3.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PVD19156.1 - 0.03 14.0 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4743 PF15916.5 PVD19156.1 - 0.085 12.8 0.3 0.86 9.6 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) TsaE PF02367.17 PVD19156.1 - 0.19 11.7 1.1 8 6.5 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2951 PF11166.8 PVD19159.1 - 0.057 13.6 0.4 0.076 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) CBP_BcsS PF17036.5 PVD19159.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS DUF2956 PF11169.8 PVD19162.1 - 0.034 14.3 1.1 0.034 14.3 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-CCHC_2 PF13696.6 PVD19163.1 - 0.037 13.8 0.6 0.037 13.8 0.6 1.6 2 0 0 2 2 2 0 Zinc knuckle MitMem_reg PF13012.6 PVD19165.1 - 5.7e-23 81.5 0.1 9.6e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PVD19165.1 - 7.2e-21 74.4 1.0 1.3e-20 73.5 0.3 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DHR-2 PF06920.13 PVD19166.1 - 9.6e-198 658.1 4.1 1.5e-197 657.5 4.1 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PVD19166.1 - 6e-50 169.8 0.1 2.1e-49 168.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 PVD19166.1 - 3.9e-31 107.8 0.7 1.3e-30 106.1 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 PVD19166.1 - 1.9e-15 57.3 1.6 7.6e-15 55.3 0.3 2.8 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 PVD19166.1 - 0.0027 17.9 0.1 0.007 16.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Lipoprotein_2 PF00921.17 PVD19166.1 - 0.027 14.0 0.7 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Borrelia lipoprotein PH_9 PF15410.6 PVD19166.1 - 0.05 14.0 2.2 0.34 11.3 0.1 3.3 3 1 1 4 4 4 0 Pleckstrin homology domain Proton_antipo_M PF00361.20 PVD19166.1 - 0.2 10.9 0.1 0.33 10.1 0.1 1.3 1 0 0 1 1 1 0 Proton-conducting membrane transporter Cullin PF00888.22 PVD19167.1 - 5.1e-225 748.8 13.7 6.5e-225 748.4 13.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PVD19167.1 - 1.2e-25 89.3 0.6 4.1e-25 87.6 0.6 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain I-set PF07679.16 PVD19169.1 - 3.2e-05 23.9 0.0 0.00017 21.6 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19169.1 - 6.2e-05 23.5 0.0 6.2e-05 23.5 0.0 6.1 6 1 0 6 6 6 1 Immunoglobulin domain ATP_transf PF09830.9 PVD19170.1 - 0.025 14.7 16.0 1.1 9.4 1.2 4.3 2 1 2 4 4 4 0 ATP adenylyltransferase SEA PF01390.20 PVD19171.1 - 0.0018 18.3 0.3 0.0018 18.3 0.3 1.9 2 0 0 2 2 2 1 SEA domain CMV_1a PF12467.8 PVD19171.1 - 0.02 15.3 0.5 0.02 15.3 0.5 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family CBM_14 PF01607.24 PVD19171.1 - 0.76 10.0 18.1 0.29 11.3 4.6 3.4 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain HMG_box_2 PF09011.10 PVD19174.1 - 0.028 15.0 0.1 0.07 13.7 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain p450 PF00067.22 PVD19175.1 - 2.5e-47 161.7 0.0 2.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SEA PF01390.20 PVD19176.1 - 1.3e-05 25.2 0.7 3.7e-05 23.8 0.7 1.7 1 0 0 1 1 1 1 SEA domain CBM_14 PF01607.24 PVD19176.1 - 0.12 12.6 16.4 0.046 13.9 2.1 3.7 3 1 1 4 4 4 0 Chitin binding Peritrophin-A domain CMV_1a PF12467.8 PVD19176.1 - 2.1 8.7 11.7 0.11 12.8 0.6 2.5 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Vpu PF00558.19 PVD19177.1 - 0.032 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Vpu protein FAM176 PF14851.6 PVD19177.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF4079 PF13301.6 PVD19177.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4044 PF13253.6 PVD19177.1 - 0.26 10.8 5.8 0.54 9.8 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4044) Plasmod_Pvs28 PF06247.11 PVD19178.1 - 0.018 15.4 0.6 0.018 15.4 0.6 1.9 1 1 1 2 2 2 0 Pvs28 EGF domain CBM_14 PF01607.24 PVD19178.1 - 2.3 8.5 6.7 4.8 7.4 6.7 1.7 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain Dimer_Tnp_hAT PF05699.14 PVD19179.1 - 0.11 12.3 2.7 0.12 12.2 0.2 2.4 3 1 0 3 3 3 0 hAT family C-terminal dimerisation region Coiled-coil_56 PF09813.9 PVD19179.1 - 0.59 10.2 3.9 0.17 12.0 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 TelA PF05816.11 PVD19181.1 - 7e-08 31.9 7.0 8.7e-08 31.6 7.0 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Occludin_ELL PF07303.13 PVD19181.1 - 9.9e-06 26.2 10.9 0.0016 19.1 6.7 2.1 2 0 0 2 2 2 1 Occludin homology domain UPF0242 PF06785.11 PVD19181.1 - 0.00071 19.7 7.2 0.00091 19.4 7.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 PVD19181.1 - 0.0025 17.9 8.9 0.0062 16.6 6.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) WXG100 PF06013.12 PVD19181.1 - 0.0026 18.0 2.7 0.0052 17.0 1.1 2.0 1 1 1 2 2 2 1 Proteins of 100 residues with WXG AIP3 PF03915.13 PVD19181.1 - 0.0039 16.4 8.0 0.0051 16.0 8.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Cor1 PF04803.12 PVD19181.1 - 0.0042 17.3 11.6 0.0055 16.9 11.6 1.1 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region Fib_alpha PF08702.10 PVD19181.1 - 0.0046 17.1 11.1 0.0066 16.6 11.1 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 PVD19181.1 - 0.0065 16.0 6.7 0.011 15.3 6.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain RRF PF01765.19 PVD19181.1 - 0.0097 15.9 8.5 0.012 15.5 8.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Muted PF14942.6 PVD19181.1 - 0.014 15.7 11.6 0.018 15.4 11.6 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Tweety PF04906.13 PVD19181.1 - 0.016 13.9 2.4 0.024 13.3 2.4 1.3 1 0 0 1 1 1 0 Tweety Apolipoprotein PF01442.18 PVD19181.1 - 0.017 15.0 8.8 0.035 14.0 8.8 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 PVD19181.1 - 0.017 13.1 7.4 0.02 12.9 7.4 1.0 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 PVD19181.1 - 0.02 15.4 9.0 3.4 8.3 9.0 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 PVD19181.1 - 0.024 14.1 14.0 0.028 13.9 14.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 PVD19181.1 - 0.025 13.9 14.6 0.035 13.5 14.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PVD19181.1 - 0.027 13.3 13.8 0.033 13.1 13.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LXG PF04740.12 PVD19181.1 - 0.029 14.1 10.6 0.2 11.4 10.7 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily Peptidase_C50 PF03568.17 PVD19181.1 - 0.032 13.4 4.1 0.038 13.1 4.1 1.0 1 0 0 1 1 1 0 Peptidase family C50 EzrA PF06160.12 PVD19181.1 - 0.044 12.0 12.9 0.088 11.0 12.9 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF16 PF01519.16 PVD19181.1 - 0.048 14.1 14.1 0.2 12.2 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 PVD19181.1 - 0.075 13.1 14.8 0.15 12.1 14.8 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 PVD19181.1 - 0.076 13.0 9.1 0.23 11.5 5.1 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF948 PF06103.11 PVD19181.1 - 0.085 13.1 8.8 0.33 11.2 2.6 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 PVD19181.1 - 0.093 11.7 11.8 0.12 11.4 11.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sec34 PF04136.15 PVD19181.1 - 0.095 12.6 10.1 0.075 12.9 6.4 2.0 2 0 0 2 2 2 0 Sec34-like family Cytochrom_B562 PF07361.11 PVD19181.1 - 0.096 13.3 7.7 0.69 10.6 3.2 2.1 1 1 1 2 2 2 0 Cytochrome b562 DUF5082 PF16888.5 PVD19181.1 - 0.099 12.9 11.6 0.33 11.2 11.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) RmuC PF02646.16 PVD19181.1 - 0.12 11.5 8.0 0.54 9.3 3.9 2.0 1 1 1 2 2 2 0 RmuC family Baculo_PEP_C PF04513.12 PVD19181.1 - 0.13 12.3 6.0 0.71 9.9 3.3 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.8 PVD19181.1 - 0.15 11.2 7.7 0.21 10.8 7.3 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF892 PF05974.12 PVD19181.1 - 0.16 12.0 5.9 0.13 12.3 4.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF892) TPR_MLP1_2 PF07926.12 PVD19181.1 - 0.18 11.9 12.9 3.5 7.7 12.4 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 PVD19181.1 - 0.2 11.8 10.7 0.21 11.7 8.8 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Jnk-SapK_ap_N PF09744.9 PVD19181.1 - 0.2 11.9 15.6 0.083 13.1 10.7 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 PVD19181.1 - 0.21 11.1 8.6 0.24 10.9 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 PVD19181.1 - 0.21 12.1 7.1 1.1 9.8 7.1 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 PVD19181.1 - 0.24 11.5 5.1 0.24 11.5 2.6 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF883 PF05957.13 PVD19181.1 - 0.26 11.9 4.9 0.24 12.0 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.14 PVD19181.1 - 0.26 11.1 11.1 0.35 10.7 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WASH_WAHD PF11945.8 PVD19181.1 - 0.27 10.7 7.3 0.19 11.2 1.2 2.1 1 1 1 2 2 2 0 WAHD domain of WASH complex Uds1 PF15456.6 PVD19181.1 - 0.27 11.4 8.9 0.27 11.4 7.7 1.6 1 1 1 2 2 2 0 Up-regulated During Septation DHR10 PF18595.1 PVD19181.1 - 0.29 11.2 15.4 0.14 12.2 10.0 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain RIC3 PF15361.6 PVD19181.1 - 0.3 11.5 15.9 0.77 10.2 3.7 2.3 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4164 PF13747.6 PVD19181.1 - 0.31 11.4 6.7 0.61 10.4 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF148 PF02520.17 PVD19181.1 - 0.31 11.2 12.0 0.28 11.3 10.4 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF148 Med9 PF07544.13 PVD19181.1 - 0.31 11.1 11.8 0.29 11.3 3.6 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mod_r PF07200.13 PVD19181.1 - 0.36 10.9 14.0 1.7 8.7 12.5 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ECH_2 PF16113.5 PVD19181.1 - 0.36 10.3 3.5 0.46 9.9 3.5 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase OmpH PF03938.14 PVD19181.1 - 0.39 11.0 15.4 0.54 10.6 10.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Uteroglobin PF01099.17 PVD19181.1 - 0.39 11.1 5.4 0.58 10.5 0.1 2.9 1 1 1 2 2 2 0 Uteroglobin family zf-C4H2 PF10146.9 PVD19181.1 - 0.4 11.0 10.7 0.58 10.4 10.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Prefoldin PF02996.17 PVD19181.1 - 0.43 10.5 14.3 0.11 12.4 2.5 2.9 1 1 2 3 3 3 0 Prefoldin subunit ApoO PF09769.9 PVD19181.1 - 0.48 10.4 4.4 9.4 6.2 4.4 2.2 1 1 0 1 1 1 0 Apolipoprotein O Spectrin PF00435.21 PVD19181.1 - 0.48 10.9 11.4 3.1 8.4 8.9 2.0 1 1 1 2 2 2 0 Spectrin repeat CdvA PF18822.1 PVD19181.1 - 0.49 10.2 12.5 0.37 10.6 4.9 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Phasin PF05597.11 PVD19181.1 - 0.5 10.4 7.9 0.53 10.3 1.4 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MCPsignal PF00015.21 PVD19181.1 - 0.61 9.9 3.5 2 8.2 3.3 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 PVD19181.1 - 0.64 10.3 12.1 0.52 10.6 1.0 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein GAT PF03127.14 PVD19181.1 - 0.66 10.3 10.2 0.45 10.9 6.2 2.4 1 1 2 3 3 3 0 GAT domain TolA_bind_tri PF16331.5 PVD19181.1 - 0.68 10.0 10.3 0.29 11.2 6.4 2.2 2 1 0 2 2 2 0 TolA binding protein trimerisation ACCA PF03255.14 PVD19181.1 - 0.69 9.8 11.5 2.6 7.9 3.5 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF745 PF05335.13 PVD19181.1 - 0.74 9.5 5.4 1 9.1 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) GPHR_N PF12537.8 PVD19181.1 - 0.77 9.9 3.0 1.5 9.0 0.3 2.3 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Helo_like_N PF17111.5 PVD19181.1 - 0.81 9.0 10.5 1.9 7.8 1.4 2.6 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins Vac_Fusion PF02346.16 PVD19181.1 - 0.85 9.3 7.1 16 5.3 4.1 3.0 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 GARP PF16731.5 PVD19181.1 - 0.91 9.2 6.0 2.5 7.7 0.5 2.6 1 1 2 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma YtxH PF12732.7 PVD19181.1 - 0.92 10.1 9.1 1.6e+02 2.9 9.1 2.4 1 1 0 1 1 1 0 YtxH-like protein Snapin_Pallidin PF14712.6 PVD19181.1 - 0.96 9.9 13.4 0.65 10.5 7.5 2.3 1 1 1 2 2 2 0 Snapin/Pallidin MIP-T3_C PF17749.1 PVD19181.1 - 0.96 9.4 12.9 1.9 8.5 1.7 2.7 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Atg14 PF10186.9 PVD19181.1 - 0.97 8.4 11.6 1.6 7.7 11.6 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 PVD19181.1 - 0.97 9.8 15.2 0.25 11.7 11.2 1.8 1 1 1 2 2 2 0 YlqD protein CLZ PF16526.5 PVD19181.1 - 0.97 9.8 11.9 8.7 6.8 6.0 3.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Z1 PF10593.9 PVD19181.1 - 0.99 8.9 6.2 1.4 8.4 6.2 1.1 1 0 0 1 1 1 0 Z1 domain YabA PF06156.13 PVD19181.1 - 1.3 9.7 11.9 2.8 8.6 7.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Sugarporin_N PF11471.8 PVD19181.1 - 1.3 9.0 3.3 25 4.9 0.9 2.6 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Allexi_40kDa PF05549.11 PVD19181.1 - 1.5 8.3 5.7 3.8 7.0 5.4 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3450 PF11932.8 PVD19181.1 - 1.7 7.9 13.8 1.3 8.3 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dad3 PF08656.10 PVD19181.1 - 1.8 8.7 7.1 9.1 6.5 4.3 2.7 1 1 0 2 2 1 0 DASH complex subunit Dad3 ING PF12998.7 PVD19181.1 - 1.8 9.2 11.0 4.5 7.9 10.6 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding FlxA PF14282.6 PVD19181.1 - 2 8.4 14.8 0.56 10.2 7.4 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF465 PF04325.13 PVD19181.1 - 2.3 8.3 9.9 0.45 10.6 1.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF465) APG6_N PF17675.1 PVD19181.1 - 2.3 8.7 14.9 4.5 7.8 14.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 PVD19181.1 - 2.5 8.4 15.6 18 5.7 5.7 2.6 1 1 1 2 2 2 0 Haemolysin XhlA CHIP_TPR_N PF18391.1 PVD19181.1 - 2.5 8.9 12.7 2 9.3 2.6 2.3 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DMPK_coil PF08826.10 PVD19181.1 - 2.6 8.2 15.5 1.3 9.2 2.8 3.1 1 1 2 3 3 3 0 DMPK coiled coil domain like DUF1515 PF07439.11 PVD19181.1 - 2.7 8.1 5.4 2.5 8.2 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) PCRF PF03462.18 PVD19181.1 - 3.1 7.6 9.7 7 6.5 9.7 1.6 1 1 0 1 1 1 0 PCRF domain Syntaxin_2 PF14523.6 PVD19181.1 - 3.2 8.2 14.2 30 5.0 14.2 2.3 1 1 0 1 1 1 0 Syntaxin-like protein RRF_GI PF12614.8 PVD19181.1 - 3.4 7.8 7.3 0.97 9.6 1.5 2.0 1 1 1 2 2 2 0 Ribosome recycling factor Mt_ATP-synt_D PF05873.12 PVD19181.1 - 3.5 7.5 10.2 8.7 6.2 10.2 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4407 PF14362.6 PVD19181.1 - 3.6 6.9 8.3 4.7 6.5 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 PVD19181.1 - 3.7 6.3 7.6 4.8 6.0 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMF_DNA_bd PF12329.8 PVD19181.1 - 4.1 7.5 16.3 8.3 6.5 9.4 2.8 1 1 2 3 3 2 0 TATA element modulatory factor 1 DNA binding TraF_2 PF13729.6 PVD19181.1 - 4.5 6.6 6.0 8 5.7 0.5 2.0 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Phage_GPO PF05929.11 PVD19181.1 - 4.6 6.8 9.8 7.5 6.1 7.1 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.13 PVD19181.1 - 5.2 6.2 11.6 12 5.0 11.0 1.7 1 1 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 PVD19181.1 - 6.3 4.6 9.4 8.3 4.2 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.13 PVD19181.1 - 6.6 6.3 10.4 7.5 6.1 4.9 2.3 1 1 1 2 2 2 0 fzo-like conserved region FlaC_arch PF05377.11 PVD19181.1 - 6.7 7.2 12.2 17 5.9 0.3 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ARD PF03079.14 PVD19181.1 - 7.1 6.8 10.7 0.68 10.1 2.8 2.0 1 1 1 2 2 2 0 ARD/ARD' family HalX PF08663.10 PVD19181.1 - 8.2 6.8 7.6 27 5.2 0.4 3.0 1 1 2 3 3 3 0 HalX domain DUF4446 PF14584.6 PVD19181.1 - 9.8 6.1 10.6 4.9 7.1 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) RNA_helicase PF00910.22 PVD19182.1 - 0.081 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 PVD19182.1 - 0.12 12.2 0.1 0.85 9.5 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase B-block_TFIIIC PF04182.12 PVD19183.1 - 0.056 13.6 5.7 21 5.4 0.2 5.5 3 2 3 6 6 6 0 B-block binding subunit of TFIIIC MMR_HSR1 PF01926.23 PVD19184.1 - 3.1e-05 24.0 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD19184.1 - 9.6e-05 22.8 0.0 0.0002 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 PVD19184.1 - 0.00034 20.9 0.1 0.00082 19.7 0.1 1.6 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 PVD19184.1 - 0.0022 17.9 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 PVD19184.1 - 0.0042 16.4 0.0 0.027 13.7 0.0 1.8 2 1 0 2 2 2 1 KAP family P-loop domain AIG1 PF04548.16 PVD19184.1 - 0.0054 16.1 3.4 0.0088 15.4 0.0 2.8 3 0 0 3 3 3 1 AIG1 family AAA_18 PF13238.6 PVD19184.1 - 0.0064 17.0 0.1 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 PVD19184.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Septin IIGP PF05049.13 PVD19184.1 - 0.0066 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 PVD19184.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 PVD19184.1 - 0.0093 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 PVD19184.1 - 0.0094 16.5 1.4 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PVD19184.1 - 0.011 15.1 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pox_A32 PF04665.12 PVD19184.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.6 PVD19184.1 - 0.012 15.8 0.0 0.03 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 PVD19184.1 - 0.015 15.3 0.8 0.015 15.3 0.8 3.0 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 PVD19184.1 - 0.017 15.6 0.2 0.051 14.1 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 PVD19184.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region OS-D PF03392.13 PVD19184.1 - 0.036 14.2 2.9 0.3 11.2 0.0 2.9 2 1 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D AAA_15 PF13175.6 PVD19184.1 - 0.037 13.7 1.8 0.09 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 PVD19184.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 PVD19184.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PVD19184.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD19184.1 - 0.056 13.9 0.0 0.31 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 7tm_7 PF08395.12 PVD19184.1 - 0.078 12.2 0.5 0.13 11.4 0.5 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor SEA PF01390.20 PVD19185.1 - 2.8e-08 33.8 0.1 7.2e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 SEA domain CBM_14 PF01607.24 PVD19185.1 - 6.4e-07 29.4 17.8 0.0016 18.6 2.6 3.5 2 1 1 3 3 3 2 Chitin binding Peritrophin-A domain TPP1 PF10341.9 PVD19186.1 - 0.091 12.7 1.1 0.26 11.3 0.5 2.0 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD SWIRM-assoc_3 PF16498.5 PVD19187.1 - 0.08 13.2 2.9 33 4.8 0.1 4.9 5 0 0 5 5 5 0 SWIRM-associated domain at the C-terminal Endonuc-PvuII PF09225.10 PVD19187.1 - 0.18 11.6 0.0 23 4.7 0.0 2.3 2 0 0 2 2 2 0 Restriction endonuclease PvuII SAVED PF18145.1 PVD19187.1 - 1.3 8.8 7.8 13 5.5 0.1 4.6 3 1 2 5 5 5 0 SMODS-associated and fused to various effectors sensor domain SFTA2 PF15210.6 PVD19188.1 - 0.037 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Surfactant-associated protein 2 SEA PF01390.20 PVD19188.1 - 0.04 14.0 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 SEA domain DUF2749 PF10907.8 PVD19189.1 - 0.27 11.4 1.3 0.88 9.8 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Tricorn_PDZ PF14685.6 PVD19190.1 - 0.15 12.1 10.4 2.2 8.3 1.5 3.9 1 1 3 4 4 4 0 Tricorn protease PDZ domain Glyco_hydro_65C PF03633.15 PVD19190.1 - 6.9 6.7 7.9 2 8.4 0.3 3.5 2 2 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain Y_phosphatase3 PF13350.6 PVD19191.1 - 0.00029 20.9 8.8 17 5.3 2.2 5.9 2 1 1 3 3 3 0 Tyrosine phosphatase family DUF5069 PF16798.5 PVD19191.1 - 0.014 15.6 13.0 2.5 8.3 0.8 5.5 1 1 6 7 7 7 0 Domain of unknown function (DUF5069) TetR_C_30 PF17939.1 PVD19191.1 - 0.021 15.0 3.7 14 6.0 0.1 4.5 2 1 2 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DDE_Tnp_IS240 PF13610.6 PVD19191.1 - 0.028 14.7 9.4 3.5 7.8 0.1 4.4 2 1 1 4 4 4 0 DDE domain ATP-synt_B PF00430.18 PVD19191.1 - 0.12 12.4 8.6 8.7 6.4 0.6 3.9 1 1 3 4 4 4 0 ATP synthase B/B' CF(0) vATP-synt_E PF01991.18 PVD19191.1 - 1.3 8.4 8.2 0.87 8.9 0.2 3.2 2 1 0 3 3 3 0 ATP synthase (E/31 kDa) subunit B12-binding_2 PF02607.17 PVD19191.1 - 4.5 7.8 5.5 3.1e+02 1.9 0.1 5.0 4 3 3 7 7 7 0 B12 binding domain PAS_7 PF12860.7 PVD19191.1 - 6.5 7.0 27.7 2.3 8.4 1.0 5.7 1 1 6 8 8 8 0 PAS fold FliG_N PF14842.6 PVD19191.1 - 6.8 7.3 12.3 22 5.7 0.2 4.7 2 1 4 6 6 6 0 FliG N-terminal domain V-ATPase_G_2 PF16999.5 PVD19191.1 - 7.3 7.1 18.2 7.3 7.1 0.9 4.6 2 1 2 5 5 5 0 Vacuolar (H+)-ATPase G subunit PAS_4 PF08448.10 PVD19191.1 - 8.8 6.6 23.2 12 6.2 1.5 6.2 1 1 5 6 6 6 0 PAS fold Glyoxalase_6 PF18029.1 PVD19192.1 - 0.00012 22.9 40.5 6.7e+02 1.1 11.1 8.6 1 1 1 2 2 2 0 Glyoxalase-like domain ACT_5 PF13710.6 PVD19192.1 - 0.00073 19.3 12.6 72 3.3 0.1 9.1 2 2 9 12 12 12 0 ACT domain Transglut_N PF00868.20 PVD19192.1 - 0.014 15.7 42.5 1.8 8.9 3.6 6.2 1 1 4 5 5 5 0 Transglutaminase family GH43_C2 PF17851.1 PVD19192.1 - 0.14 11.8 19.3 2.6 7.7 4.7 3.7 1 1 2 3 3 3 0 Beta xylosidase C-terminal Concanavalin A-like domain GDE_N PF12439.8 PVD19192.1 - 0.43 10.0 27.3 0.97 8.8 4.7 4.0 1 1 2 4 4 4 0 Glycogen debranching enzyme N terminal Whirly PF08536.11 PVD19192.1 - 2.7 7.8 11.7 62 3.4 0.2 5.0 2 2 4 6 6 6 0 Whirly transcription factor Dimer_Tnp_hAT PF05699.14 PVD19194.1 - 0.0003 20.5 0.1 0.00047 19.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region tRNA-synt_2c PF01411.19 PVD19195.1 - 1.9e-117 393.1 0.1 2e-60 204.9 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PVD19195.1 - 4.3e-13 49.1 1.3 9.5e-13 48.0 1.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CHASE3 PF05227.13 PVD19195.1 - 0.36 10.7 3.8 0.14 12.0 1.0 1.7 2 0 0 2 2 2 0 CHASE3 domain Utp12 PF04003.12 PVD19195.1 - 6.6 7.1 6.3 1 9.7 0.6 2.4 3 0 0 3 3 3 0 Dip2/Utp12 Family 7tm_1 PF00001.21 PVD19196.1 - 7.7e-34 117.2 10.7 9.4e-34 116.9 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19196.1 - 6.6e-10 39.0 9.4 9.5e-10 38.5 9.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Trp_oprn_chp PF09534.10 PVD19196.1 - 0.036 13.9 1.2 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 7TM_GPCR_Sra PF02117.16 PVD19196.1 - 0.047 12.5 2.6 0.087 11.6 1.1 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra Phage_holin_5_2 PF16079.5 PVD19196.1 - 0.47 10.8 3.4 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V OATP PF03137.20 PVD19197.1 - 2.8e-62 210.7 0.0 3.4e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD19197.1 - 1.4e-05 24.2 16.4 0.00019 20.5 16.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1269 PF06897.12 PVD19197.1 - 0.072 13.4 2.0 0.12 12.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) OATP PF03137.20 PVD19198.1 - 6.6e-07 28.0 0.2 7e-07 27.9 0.2 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 PVD19198.1 - 0.0018 18.4 3.2 0.0027 17.8 3.2 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.20 PVD19199.1 - 5.8e-12 44.7 7.1 2.6e-11 42.5 7.1 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AurF PF11583.8 PVD19199.1 - 0.25 10.6 0.0 0.33 10.2 0.0 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF cNMP_binding PF00027.29 PVD19200.1 - 1.9e-41 140.0 0.2 5.9e-24 84.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 PVD19200.1 - 1.4e-08 34.2 0.0 3.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Y_phosphatase PF00102.27 PVD19202.1 - 9.5e-65 218.4 0.0 1.6e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD19202.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD19202.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.20 PVD19202.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4690 PF15756.5 PVD19202.1 - 0.23 12.1 3.1 0.4 11.3 0.1 2.5 2 0 0 2 2 2 0 Small Novel Rich in Cartilage YTH PF04146.15 PVD19204.1 - 3e-43 147.6 0.8 2e-41 141.7 0.8 2.6 1 1 0 1 1 1 1 YT521-B-like domain HA2 PF04408.23 PVD19204.1 - 4.2e-18 65.6 0.1 1.7e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PVD19204.1 - 2.7e-14 53.5 0.1 8.4e-14 51.9 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain R3H PF01424.22 PVD19204.1 - 5.1e-12 45.6 0.0 1.9e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 PVD19204.1 - 2.5e-11 43.7 0.0 5.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 PVD19204.1 - 6.9e-11 42.4 0.1 1.9e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ank_2 PF12796.7 PVD19204.1 - 2.4e-06 28.0 0.0 9.1e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_19 PF13245.6 PVD19204.1 - 8.2e-05 23.0 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD19204.1 - 0.0013 17.8 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Ank_5 PF13857.6 PVD19204.1 - 0.0013 18.9 0.3 0.014 15.7 0.0 2.7 3 0 0 3 3 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 PVD19204.1 - 0.0025 18.2 1.3 0.014 15.7 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain ATPase PF06745.13 PVD19204.1 - 0.016 14.6 0.1 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 PVD19204.1 - 0.019 15.2 0.1 0.093 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 PVD19204.1 - 0.027 14.0 0.2 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 PVD19204.1 - 0.029 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 PVD19204.1 - 0.029 13.9 0.1 0.077 12.5 0.1 1.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 PVD19204.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PVD19204.1 - 0.086 12.9 0.0 1.7 8.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 PVD19204.1 - 0.095 12.7 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Myosin_head PF00063.21 PVD19204.1 - 0.11 10.7 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Ank PF00023.30 PVD19204.1 - 0.11 13.0 0.0 44 4.8 0.0 3.4 2 0 0 2 2 2 0 Ankyrin repeat Sigma54_activat PF00158.26 PVD19204.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytochrom_B559 PF00283.19 PVD19204.1 - 0.17 11.3 1.5 0.39 10.2 1.5 1.5 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Gal-3-0_sulfotr PF06990.11 PVD19205.1 - 3.9e-39 134.7 1.6 5.4e-39 134.2 1.6 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Swi3 PF07962.12 PVD19206.1 - 2.8e-24 84.9 0.0 5.8e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Sulfotransfer_2 PF03567.14 PVD19207.1 - 9e-26 91.3 2.4 1.3e-22 80.9 1.1 3.1 2 1 0 2 2 2 2 Sulfotransferase family PPARgamma_N PF12577.8 PVD19208.1 - 0.001 19.6 30.1 0.47 11.1 7.0 3.5 1 1 2 3 3 3 3 PPAR gamma N-terminal region rve_2 PF13333.6 PVD19208.1 - 0.0017 18.5 7.3 64 3.8 1.2 7.3 1 1 1 2 2 2 0 Integrase core domain Pox_A31 PF05771.11 PVD19208.1 - 0.0048 16.9 8.8 0.78 9.8 0.8 3.3 1 1 1 2 2 2 2 Poxvirus A31 protein Phage_lysozyme PF00959.19 PVD19208.1 - 0.013 15.9 6.4 0.064 13.7 0.7 3.1 1 1 1 2 2 2 0 Phage lysozyme bPH_3 PF14470.6 PVD19208.1 - 0.033 14.5 11.8 9.6e+03 -3.0 11.5 5.1 1 1 0 1 1 1 0 Bacterial PH domain DASH_Hsk3 PF08227.11 PVD19208.1 - 0.16 12.4 17.1 26 5.3 0.1 7.0 1 1 5 7 7 7 0 DASH complex subunit Hsk3 like Sof1 PF04158.14 PVD19208.1 - 2.3 8.5 8.3 33 4.8 0.3 3.7 1 1 1 3 3 3 0 Sof1-like domain OAR PF03826.17 PVD19209.1 - 4.5e-07 29.5 0.4 7.9e-07 28.7 0.4 1.4 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 PVD19209.1 - 0.00061 19.6 4.5 0.0013 18.6 4.5 1.5 1 0 0 1 1 1 1 Homeodomain Yae1_N PF09811.9 PVD19210.1 - 0.017 14.8 23.7 1.8 8.3 1.8 3.7 2 1 0 2 2 2 0 Essential protein Yae1, N terminal OLF PF02191.16 PVD19211.1 - 2.1e-58 197.8 0.0 1.3e-29 103.5 0.0 2.0 2 0 0 2 2 2 2 Olfactomedin-like domain 7tm_1 PF00001.21 PVD19212.1 - 7.6e-12 45.1 0.2 1.3e-09 37.8 0.2 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glutaredoxin PF00462.24 PVD19213.1 - 1.3e-14 54.1 0.1 3.5e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin 7tm_1 PF00001.21 PVD19213.1 - 5.1e-08 32.6 1.7 5.1e-08 32.6 1.7 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Thioredoxin_3 PF13192.6 PVD19213.1 - 0.0092 16.0 0.1 0.023 14.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 PVD19213.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 PVD19213.1 - 0.044 13.6 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 PVD19213.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 PVD19213.1 - 0.17 12.1 0.2 4.2 7.5 0.2 2.2 1 1 0 2 2 2 0 Thioredoxin Serinc PF03348.15 PVD19214.1 - 1.2e-95 321.0 17.7 5.8e-66 223.2 2.5 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) F5_F8_type_C PF00754.25 PVD19217.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain IGFBP PF00219.18 PVD19219.1 - 1.4e-08 35.3 19.4 3.6e-08 33.9 19.4 1.7 1 0 0 1 1 1 1 Insulin-like growth factor binding protein Pkinase PF00069.25 PVD19221.1 - 2.6e-62 210.6 0.0 3.3e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD19221.1 - 6e-25 88.0 0.0 8.4e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD19221.1 - 0.015 15.2 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PVD19221.1 - 0.18 10.7 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Band_7_C PF16200.5 PVD19222.1 - 7e-26 90.1 2.8 7e-26 90.1 2.8 1.9 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7 PF01145.25 PVD19222.1 - 1.5e-17 64.2 2.1 6.1e-17 62.2 2.1 2.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family VWA PF00092.28 PVD19223.1 - 4.7e-45 154.0 0.0 2.4e-33 115.8 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19223.1 - 1.2e-09 38.8 0.0 6.6e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain Integrin_beta PF00362.18 PVD19223.1 - 0.0031 17.2 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrin beta chain VWA domain DUF4805 PF16063.5 PVD19224.1 - 0.48 9.7 4.6 6.7 6.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4805) C1q PF00386.21 PVD19225.1 - 3.7e-10 40.1 0.7 4.8e-10 39.7 0.1 1.5 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 PVD19225.1 - 0.057 13.3 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 BclA C-terminal domain C1q PF00386.21 PVD19226.1 - 1e-11 45.1 0.1 1.3e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD19226.1 - 6.9e-05 22.8 0.2 8.7e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 BclA C-terminal domain DUF4843 PF16132.5 PVD19226.1 - 0.052 13.1 0.1 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) 7TM_GPCR_Srx PF10328.9 PVD19227.1 - 0.0005 19.8 1.8 0.00058 19.6 1.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx C1q PF00386.21 PVD19228.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD19228.1 - 0.046 13.6 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 BclA C-terminal domain VWA PF00092.28 PVD19229.1 - 2.7e-07 31.0 0.2 4.2e-07 30.4 0.2 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19229.1 - 0.057 14.1 0.0 0.14 12.9 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain PMC2NT PF08066.12 PVD19229.1 - 0.16 12.7 1.3 1.9 9.2 1.3 2.1 1 1 0 1 1 1 0 PMC2NT (NUC016) domain VWA PF00092.28 PVD19230.1 - 3.4e-26 92.6 0.1 3.8e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19230.1 - 4.4e-09 36.9 0.3 7.7e-09 36.2 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD19230.1 - 8.5e-05 22.5 0.4 0.00011 22.2 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD19230.1 - 0.012 15.0 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein VWA PF00092.28 PVD19232.1 - 6e-08 33.1 0.0 7.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain PMC2NT PF08066.12 PVD19232.1 - 0.029 15.0 1.4 0.47 11.2 1.4 2.2 1 1 0 1 1 1 0 PMC2NT (NUC016) domain KfrA_N PF11740.8 PVD19232.1 - 0.11 13.2 0.0 1.3 9.7 0.0 2.0 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term VWA PF00092.28 PVD19233.1 - 5.8e-25 88.5 0.1 6.6e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19233.1 - 1.2e-08 35.6 0.2 2e-08 34.8 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD19233.1 - 5.4e-05 23.2 0.4 7e-05 22.8 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD19233.1 - 0.073 12.4 0.2 0.087 12.2 0.2 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Aldedh PF00171.22 PVD19235.1 - 4.1e-95 319.0 0.2 8.3e-62 209.2 0.0 3.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Branch PF02485.21 PVD19237.1 - 2.7e-29 102.4 0.0 3.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme 7TM_GPCR_Srw PF10324.9 PVD19238.1 - 4.1e-10 39.4 7.3 4.1e-10 39.4 7.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD19238.1 - 0.00011 21.9 5.0 0.00011 21.9 5.0 2.2 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD19239.1 - 1.7e-09 37.4 19.2 2.4e-09 36.9 19.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD19240.1 - 0.00022 21.0 2.6 0.00025 20.8 2.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD19240.1 - 0.0066 15.9 5.4 0.0086 15.5 5.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD19240.1 - 0.036 13.3 3.8 0.042 13.1 3.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD19241.1 - 1.7e-05 24.3 19.0 4.4e-05 22.9 19.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19241.1 - 0.00017 21.3 13.2 0.00017 21.3 13.2 2.4 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Tmemb_9 PF05434.11 PVD19241.1 - 0.24 11.3 1.1 0.88 9.5 0.2 2.1 2 0 0 2 2 2 0 TMEM9 Mito_fiss_reg PF05308.11 PVD19244.1 - 0.24 11.4 2.5 0.22 11.6 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD19244.1 - 0.26 10.8 5.3 0.31 10.5 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ion_trans PF00520.31 PVD19245.1 - 0.0067 15.7 0.4 0.011 15.0 0.4 1.2 1 0 0 1 1 1 1 Ion transport protein DivIC PF04977.15 PVD19245.1 - 8.5 6.2 5.9 9 6.1 3.1 2.3 1 1 1 2 2 2 0 Septum formation initiator zf-C2H2_4 PF13894.6 PVD19246.1 - 6.1e-29 98.2 100.8 0.0049 17.6 1.4 16.5 15 0 0 15 15 15 13 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD19246.1 - 6e-23 80.0 101.7 0.00025 21.3 1.1 16.2 16 0 0 16 16 16 11 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD19246.1 - 3.8e-17 62.1 38.2 0.035 14.4 0.1 12.7 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD19246.1 - 4.8e-09 36.3 61.3 0.0041 17.5 0.1 12.5 13 0 0 13 13 12 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 PVD19246.1 - 1.9e-07 31.2 93.3 0.039 14.4 0.1 15.4 16 0 0 16 16 14 6 Zinc-finger double domain zf-C2H2_8 PF15909.5 PVD19246.1 - 0.00014 22.1 0.7 0.00014 22.1 0.7 7.5 4 2 5 9 9 9 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PVD19246.1 - 0.00014 21.7 83.7 0.0027 17.6 0.4 13.0 14 1 0 14 14 13 5 C2H2-type zinc finger BolA PF01722.18 PVD19246.1 - 0.0048 17.1 7.1 4.8 7.5 0.0 5.4 4 1 1 5 5 5 1 BolA-like protein zf-C2H2_11 PF16622.5 PVD19246.1 - 0.0099 15.6 0.3 0.026 14.3 0.2 9.3 10 0 0 10 10 10 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 PVD19246.1 - 0.022 14.6 0.2 0.022 14.6 0.2 7.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 PVD19246.1 - 0.3 11.1 0.1 0.3 11.1 0.1 5.7 6 2 1 7 7 7 0 Adenylate kinase, active site lid BUD22 PF09073.10 PVD19246.1 - 1 8.6 15.3 2.4 7.4 15.3 1.5 1 0 0 1 1 1 0 BUD22 zf-C2H2_3rep PF18868.1 PVD19246.1 - 1.6 9.4 55.1 0.22 12.2 9.1 10.3 5 2 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 PVD19246.1 - 3.8 7.4 31.1 27 4.7 0.0 8.6 7 2 1 8 8 8 0 C2H2 type zinc-finger (1 copy) UPF1_Zn_bind PF09416.10 PVD19247.1 - 5.9e-76 253.6 3.2 6.5e-75 250.2 2.9 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 PVD19247.1 - 3.1e-58 196.7 0.0 5.8e-58 195.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD19247.1 - 7.5e-46 157.0 4.1 4.1e-28 98.9 0.5 2.5 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 PVD19247.1 - 1.4e-34 118.2 0.0 2.9e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 PVD19247.1 - 1.6e-13 50.8 0.0 2.6e-12 46.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD19247.1 - 2.4e-10 40.9 0.0 8.4e-10 39.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 PVD19247.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PVD19247.1 - 0.0001 21.7 0.0 0.0048 16.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 PVD19247.1 - 0.00019 21.3 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 PVD19247.1 - 0.00097 18.7 0.3 0.0094 15.5 0.0 2.4 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 PVD19247.1 - 0.0038 16.6 0.0 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 KaiC DEAD PF00270.29 PVD19247.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase SRP54 PF00448.22 PVD19247.1 - 0.028 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 PVD19247.1 - 0.045 12.9 0.0 5.6 6.0 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase Phage_spike_2 PF18781.1 PVD19247.1 - 0.071 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage spike trimer PhoH PF02562.16 PVD19247.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 PVD19247.1 - 0.14 12.5 0.1 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD19247.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RCR PF12273.8 PVD19247.1 - 0.51 11.0 3.2 0.4 11.4 1.2 1.8 2 0 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red CTD_bind PF04818.13 PVD19250.1 - 3.1e-18 66.4 0.8 3.1e-18 66.4 0.8 3.5 4 1 0 4 4 4 1 RNA polymerase II-binding domain. CREPT PF16566.5 PVD19250.1 - 0.00025 21.3 2.8 0.00025 21.3 2.8 2.6 2 1 1 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour Herpes_ICP4_N PF03584.15 PVD19250.1 - 0.039 13.8 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region Fringe PF02434.16 PVD19251.1 - 2.3e-10 40.3 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD19251.1 - 0.0045 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.6 PVD19251.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 CHGN PF05679.16 PVD19252.1 - 2.3e-138 462.2 0.5 3e-80 270.5 0.1 2.0 1 1 1 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 PVD19252.1 - 8.5e-11 41.4 0.1 1.8e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PVD19252.1 - 0.005 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CLAMP PF14769.6 PVD19252.1 - 0.029 14.8 0.2 0.059 13.8 0.2 1.4 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Peptidase_M54 PF07998.11 PVD19253.1 - 3e-05 24.1 3.2 4e-05 23.7 2.4 1.6 2 0 0 2 2 2 1 Peptidase family M54 DUF1230 PF06799.11 PVD19253.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.7 1 1 1 2 2 2 0 Conserved in the green lineage and diatoms 27 GAF PF01590.26 PVD19253.1 - 0.16 12.6 0.1 0.65 10.6 0.0 2.1 3 0 0 3 3 3 0 GAF domain UPF0054 PF02130.17 PVD19253.1 - 0.24 11.2 1.8 0.6 9.9 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein family UPF0054 mRNA_cap_enzyme PF01331.19 PVD19254.1 - 0.00079 19.3 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Peptidase_M28 PF04389.17 PVD19256.1 - 5e-08 32.9 0.0 5.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Fibrinogen_C PF00147.18 PVD19257.1 - 1.1e-34 120.2 2.4 1.5e-34 119.7 2.4 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD19257.1 - 9.9e-05 22.2 2.3 0.0003 20.7 2.3 1.8 1 0 0 1 1 1 1 PAN domain EGF_2 PF07974.13 PVD19257.1 - 0.0026 18.1 2.6 0.0026 18.1 2.6 2.5 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 PVD19257.1 - 0.017 15.8 4.3 0.017 15.8 4.3 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF PAN_4 PF14295.6 PVD19257.1 - 0.062 13.2 2.1 0.21 11.5 2.1 2.0 1 0 0 1 1 1 0 PAN domain Laminin_EGF PF00053.24 PVD19257.1 - 6.7 7.0 17.0 21 5.3 11.7 3.3 2 1 0 2 2 2 0 Laminin EGF domain Fibrinogen_C PF00147.18 PVD19258.1 - 1.5e-08 34.8 0.2 2e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain 7TM_GPCR_Srw PF10324.9 PVD19259.1 - 0.00088 18.6 9.8 0.0014 18.0 2.9 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD19259.1 - 0.0012 18.2 11.7 0.0079 15.5 3.2 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Wzy_C_2 PF11846.8 PVD19261.1 - 4 7.3 5.6 1.2 9.0 1.8 2.0 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal MFS_1 PF07690.16 PVD19262.1 - 6.6e-12 45.0 13.0 1.3e-11 44.1 13.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD19262.1 - 0.00068 18.6 0.8 0.00068 18.6 0.8 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 PVD19262.1 - 0.012 14.0 0.7 0.018 13.5 0.7 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_4 PF06779.14 PVD19262.1 - 0.025 13.9 2.8 0.026 13.8 1.6 1.6 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB FUSC_2 PF13515.6 PVD19262.1 - 0.049 13.7 3.7 0.089 12.9 3.4 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein-like FtsX PF02687.21 PVD19262.1 - 0.11 13.0 12.2 0.32 11.5 8.2 2.8 2 1 0 2 2 2 0 FtsX-like permease family MFS_1 PF07690.16 PVD19263.1 - 1.3e-20 73.6 36.7 1.3e-20 73.6 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_9 PF14580.6 PVD19264.1 - 9e-11 41.6 0.2 1.5e-10 40.9 0.1 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PVD19264.1 - 2.6e-10 40.4 12.9 6.7e-06 26.4 2.5 3.0 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD19264.1 - 5.1e-10 39.0 12.9 3.2e-06 26.8 2.6 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 PVD19264.1 - 0.18 11.9 13.6 0.36 11.0 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 PVD19264.1 - 0.23 12.1 12.0 5.1 8.0 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat 7TM_GPCR_Srx PF10328.9 PVD19265.1 - 0.0022 17.7 11.3 0.011 15.4 10.0 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD19265.1 - 0.02 14.9 3.5 0.032 14.2 3.2 1.5 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Srg PF02118.21 PVD19265.1 - 0.15 11.7 6.9 0.026 14.2 2.7 1.7 1 1 0 2 2 2 0 Srg family chemoreceptor 7tm_1 PF00001.21 PVD19265.1 - 0.8 9.0 7.4 0.64 9.3 3.2 2.0 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19266.1 - 2.1e-15 57.0 33.3 0.00025 20.8 5.4 5.3 5 0 0 5 5 5 5 Serpentine type 7TM GPCR chemoreceptor Srx IlvB_leader PF08049.11 PVD19266.1 - 6e-14 51.7 7.0 0.0026 17.6 0.2 6.1 5 0 0 5 5 5 5 IlvB leader peptide Srg PF02118.21 PVD19266.1 - 5.2e-09 36.2 38.6 0.00043 20.0 5.0 5.2 5 0 0 5 5 5 5 Srg family chemoreceptor Collagen PF01391.18 PVD19266.1 - 2.7e-05 23.8 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.21 PVD19266.1 - 6.4e-05 22.4 43.1 0.25 10.7 0.9 5.4 4 2 0 5 5 5 5 7 transmembrane receptor (rhodopsin family) DUF218 PF02698.17 PVD19266.1 - 0.016 15.3 6.3 8.6 6.4 0.0 5.2 6 0 0 6 6 6 0 DUF218 domain Kelch_3 PF13415.6 PVD19266.1 - 0.12 12.7 0.0 65 4.0 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Serpentine_r_xa PF03383.15 PVD19266.1 - 0.24 11.4 26.7 3.5 7.6 0.3 5.7 6 0 0 6 6 6 0 Caenorhabditis serpentine receptor-like protein, class xa Forkhead_N PF08430.12 PVD19266.1 - 0.25 11.9 9.3 0.51 11.0 9.3 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region 7TM_GPCR_Srw PF10324.9 PVD19267.1 - 2e-05 24.1 3.1 2.6e-05 23.7 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 PVD19267.1 - 0.00056 19.7 3.3 0.0008 19.2 3.3 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD19267.1 - 0.0015 18.3 8.9 0.0027 17.4 8.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CitMHS PF03600.16 PVD19267.1 - 0.021 14.0 0.4 0.024 13.9 0.4 1.1 1 0 0 1 1 1 0 Citrate transporter FtsX PF02687.21 PVD19267.1 - 0.095 13.2 2.4 0.15 12.5 2.1 1.5 1 1 0 1 1 1 0 FtsX-like permease family 7tm_1 PF00001.21 PVD19268.1 - 8.4e-08 31.8 13.0 1.4e-07 31.1 13.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Transglut_core PF01841.19 PVD19269.1 - 2.5e-05 24.7 0.1 5.6e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gly_transf_sug PF04488.15 PVD19270.1 - 1.9e-08 34.8 0.0 4.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD19270.1 - 0.00025 20.5 0.2 0.00033 20.2 0.2 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Transglut_core PF01841.19 PVD19271.1 - 1.2e-05 25.7 0.0 3.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily CBM_35 PF16990.5 PVD19271.1 - 0.054 13.7 0.1 0.49 10.7 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) Bax1-I PF01027.20 PVD19272.1 - 6.5e-17 62.1 15.0 7.5e-17 61.8 15.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4191 PF13829.6 PVD19272.1 - 0.16 11.3 6.3 0.22 10.8 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF983 PF06170.12 PVD19272.1 - 1.8 9.0 14.6 2.3 8.7 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Halogen_Hydrol PF10112.9 PVD19272.1 - 1.9 8.4 5.1 2.3 8.2 5.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3040 PF11239.8 PVD19272.1 - 3.5 8.0 10.3 5.8 7.2 9.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF2070 PF09843.9 PVD19272.1 - 5.4 5.2 12.3 6 5.0 12.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PhoR PF11808.8 PVD19272.1 - 8.6 6.9 8.0 5.7 7.4 6.2 1.6 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR Asparaginase_2 PF01112.18 PVD19273.1 - 8.7e-64 215.5 2.4 1.1e-63 215.1 2.4 1.1 1 0 0 1 1 1 1 Asparaginase Arrestin_N PF00339.29 PVD19274.1 - 9.1e-37 126.3 0.0 1.2e-35 122.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19274.1 - 1.2e-24 87.3 0.0 1.8e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19274.1 - 0.0011 18.2 0.0 0.033 13.4 0.0 2.3 3 0 0 3 3 3 1 Rgp1 Vps26 PF03643.15 PVD19274.1 - 0.057 12.4 0.0 0.61 9.0 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 DUF3330 PF11809.8 PVD19274.1 - 0.058 13.5 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Arrestin_N PF00339.29 PVD19275.1 - 6.3e-22 78.2 0.0 7.5e-17 61.7 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19275.1 - 4.7e-18 65.9 0.1 1.9e-16 60.7 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19275.1 - 1.1e-05 24.8 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 Rgp1 LDB19 PF13002.7 PVD19275.1 - 0.01 15.5 0.0 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like Arrestin_N PF00339.29 PVD19276.1 - 2.2e-111 368.4 0.1 4.1e-36 124.2 0.0 3.8 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19276.1 - 1.2e-55 187.6 0.0 1.7e-14 54.4 0.0 6.5 6 0 0 6 6 6 6 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19276.1 - 2e-06 27.3 7.4 1.8 7.6 0.1 6.4 7 1 1 8 8 8 3 Rgp1 LDB19 PF13002.7 PVD19276.1 - 4.7e-06 26.4 0.0 0.6 9.8 0.0 3.3 3 0 0 3 3 3 2 Arrestin_N terminal like DUF3330 PF11809.8 PVD19276.1 - 6.9e-06 26.0 7.6 0.09 12.9 0.4 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3330) Vps26 PF03643.15 PVD19276.1 - 4.7e-05 22.5 0.0 2.8 6.9 0.0 5.4 6 1 0 6 6 6 1 Vacuolar protein sorting-associated protein 26 DUF5033 PF16436.5 PVD19276.1 - 0.00052 20.0 0.0 8.2 6.3 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF5033) DUF2393 PF09624.10 PVD19276.1 - 0.00057 19.9 0.0 3.6 7.6 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2393) Peptidase_M10_C PF08548.11 PVD19276.1 - 0.015 15.2 0.1 5 7.0 0.0 2.8 3 0 0 3 3 3 0 Peptidase M10 serralysin C terminal Arrestin_N PF00339.29 PVD19277.1 - 1.6e-36 125.6 0.0 5.3e-36 123.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19277.1 - 8.1e-22 78.1 0.0 4.6e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19277.1 - 0.0019 17.4 0.2 0.47 9.6 0.0 2.8 2 1 1 3 3 3 2 Rgp1 Vps26 PF03643.15 PVD19277.1 - 0.014 14.5 0.0 0.051 12.6 0.0 1.8 2 1 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 DUF3330 PF11809.8 PVD19277.1 - 0.04 14.0 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) LDB19 PF13002.7 PVD19277.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like DUF4518 PF15008.6 PVD19279.1 - 1.1e-49 169.1 3.2 2.2e-49 168.1 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) YadA_anchor PF03895.15 PVD19279.1 - 9.5 6.4 12.4 63 3.8 0.2 4.6 3 1 1 4 4 4 0 YadA-like membrane anchor domain DUF4518 PF15008.6 PVD19280.1 - 1.1e-47 162.5 3.1 2.1e-47 161.6 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) DUF3110 PF11360.8 PVD19280.1 - 0.061 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Neil1-DNA_bind PF09292.10 PVD19281.1 - 4.3e-19 68.2 1.6 8.8e-19 67.2 1.6 1.5 1 0 0 1 1 1 1 Endonuclease VIII-like 1, DNA bind Fapy_DNA_glyco PF01149.24 PVD19281.1 - 3.1e-14 53.6 0.1 6.2e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 PVD19281.1 - 4.5e-07 29.8 0.0 9.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FAM176 PF14851.6 PVD19282.1 - 0.17 11.5 1.3 0.35 10.5 0.3 2.0 2 0 0 2 2 2 0 FAM176 family TIR_2 PF13676.6 PVD19283.1 - 3e-45 153.6 0.0 5.7e-21 75.3 0.0 3.5 3 0 0 3 3 3 2 TIR domain Death PF00531.22 PVD19283.1 - 2.6e-12 46.7 0.4 6.6e-12 45.4 0.4 1.8 1 0 0 1 1 1 1 Death domain Adaptin_N PF01602.20 PVD19283.1 - 3.1e-07 29.3 3.7 7.6e-07 28.1 3.7 1.6 1 0 0 1 1 1 1 Adaptin N terminal region TIR PF01582.20 PVD19283.1 - 3.6e-06 26.9 0.0 0.085 12.6 0.0 3.0 2 0 0 2 2 2 2 TIR domain SlyX PF04102.12 PVD19283.1 - 0.11 13.1 1.4 0.49 11.0 1.4 2.2 1 0 0 1 1 1 0 SlyX MMS19_N PF14500.6 PVD19283.1 - 0.15 11.7 0.3 4.9 6.7 0.0 3.2 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II FACT-Spt16_Nlob PF14826.6 PVD19283.1 - 0.32 10.8 2.0 0.85 9.4 2.0 1.7 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain DUF16 PF01519.16 PVD19283.1 - 2.5 8.7 12.5 0.058 13.9 3.7 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF829 PF05705.14 PVD19284.1 - 9.9e-30 104.2 0.3 1.9e-29 103.3 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) Baculo_p24 PF05073.12 PVD19284.1 - 0.034 14.0 0.2 0.076 12.8 0.0 1.6 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Hydrolase_4 PF12146.8 PVD19284.1 - 0.048 12.9 0.0 1.7 7.9 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 MIB_HERC2 PF06701.13 PVD19285.1 - 8.9e-18 64.3 21.8 3.8e-15 55.9 8.1 2.7 2 0 0 2 2 2 2 Mib_herc2 WWE PF02825.20 PVD19285.1 - 1.7e-05 25.3 5.0 0.00028 21.4 0.6 2.9 2 0 0 2 2 2 1 WWE domain DUF445 PF04286.12 PVD19285.1 - 0.0093 15.8 0.1 0.046 13.5 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF445) DUF257 PF03192.13 PVD19285.1 - 0.032 14.0 0.1 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 VWA PF00092.28 PVD19285.1 - 0.035 14.3 0.5 8.3 6.6 0.1 2.7 1 1 1 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19285.1 - 0.14 12.9 0.4 1.5 9.5 0.0 3.0 3 1 2 5 5 5 0 von Willebrand factor type A domain Sec3_C_2 PF15278.6 PVD19285.1 - 0.71 10.3 3.5 19 5.7 0.0 3.1 2 1 1 3 3 3 0 Sec3 exocyst complex subunit Mak10 PF04112.13 PVD19286.1 - 1.8e-29 102.4 2.8 3.8e-23 81.8 0.2 2.9 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Aldose_epim PF01263.20 PVD19287.1 - 1.6e-26 93.3 0.0 2.1e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2207 PF09972.9 PVD19288.1 - 0.0002 20.3 2.2 0.0003 19.7 2.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 PVD19288.1 - 0.0033 17.2 0.9 0.0059 16.3 0.9 1.3 1 0 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 PVD19288.1 - 0.075 12.7 7.0 0.13 11.9 7.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Amnionless PF14828.6 PVD19288.1 - 0.13 11.0 2.9 0.52 9.1 2.9 1.7 1 1 0 1 1 1 0 Amnionless Shisa PF13908.6 PVD19288.1 - 1.3 9.2 9.8 11 6.2 9.8 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MMPL PF03176.15 PVD19288.1 - 2.8 6.8 12.0 0.24 10.3 6.9 1.7 2 0 0 2 2 2 0 MMPL family Herpes_LMP1 PF05297.11 PVD19288.1 - 3.7 6.6 5.8 6 6.0 5.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VWA_2 PF13519.6 PVD19289.1 - 1.5e-05 25.6 0.8 4.2e-05 24.1 0.2 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain PRKG1_interact PF15898.5 PVD19290.1 - 0.0051 17.7 11.8 0.0051 17.7 11.8 3.6 4 0 0 4 4 4 1 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.6 PVD19290.1 - 1.1 9.7 17.9 0.86 10.0 7.8 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Cadherin_3 PF16184.5 PVD19291.1 - 1.3e-196 640.1 54.7 1.3e-29 102.4 0.1 15.4 15 0 0 15 15 15 15 Cadherin-like Laminin_G_2 PF02210.24 PVD19291.1 - 6.4e-52 175.4 2.7 6e-28 97.9 0.2 3.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD19291.1 - 6.9e-41 139.5 0.8 6.9e-20 71.6 0.0 3.4 3 0 0 3 3 3 2 Laminin G domain Laminin_G_3 PF13385.6 PVD19291.1 - 2.8e-06 27.5 0.0 0.0066 16.6 0.0 4.2 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD19291.1 - 0.0042 17.4 7.6 0.0078 16.5 7.6 1.4 1 0 0 1 1 1 1 EGF-like domain DUF5305 PF17231.2 PVD19291.1 - 0.018 14.4 0.1 0.097 12.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 PVD19291.1 - 0.056 14.3 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD19291.1 - 0.06 13.2 0.0 0.06 13.2 0.0 4.1 3 0 0 3 3 3 0 TMEM154 protein family Podoplanin PF05808.11 PVD19291.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.5 2 1 0 3 3 3 0 Podoplanin A_deaminase PF00962.22 PVD19292.1 - 8.4e-31 107.5 0.4 1.1e-30 107.1 0.4 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 PVD19292.1 - 0.006 15.9 0.0 0.0092 15.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family DUF3220 PF11516.8 PVD19292.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Arrestin_N PF00339.29 PVD19293.1 - 3.1e-37 127.9 0.0 1.4e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19293.1 - 3.4e-26 92.3 0.0 9.2e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19293.1 - 0.00014 21.2 0.2 0.0035 16.6 0.1 2.3 2 1 0 2 2 2 1 Rgp1 Vps26 PF03643.15 PVD19293.1 - 0.0039 16.2 0.0 0.012 14.6 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LDB19 PF13002.7 PVD19293.1 - 0.028 14.1 0.1 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like Arrestin_N PF00339.29 PVD19294.1 - 2.7e-28 98.8 0.1 5.2e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19294.1 - 7e-08 33.0 0.0 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 PVD19294.1 - 0.005 15.9 0.0 0.011 14.7 0.0 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 PVD19294.1 - 0.058 12.6 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Rgp1 DUF885 PF05960.11 PVD19295.1 - 2.5e-131 439.9 0.0 3.1e-131 439.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) ING PF12998.7 PVD19295.1 - 0.17 12.5 1.8 11 6.7 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF885 PF05960.11 PVD19296.1 - 1.5e-127 427.5 0.0 1.9e-127 427.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF885 PF05960.11 PVD19297.1 - 7.4e-134 448.3 0.0 8.4e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Pollen_allerg_1 PF01357.21 PVD19298.1 - 0.00096 19.1 0.0 0.0056 16.7 0.0 2.1 2 0 0 2 2 2 1 Pollen allergen Pollen_allerg_1 PF01357.21 PVD19299.1 - 3.3e-07 30.2 0.1 5.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Pollen allergen Zip PF02535.22 PVD19301.1 - 9.2e-38 130.3 14.5 7.2e-29 101.0 3.4 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter FoP_duplication PF13865.6 PVD19301.1 - 0.33 11.5 0.1 0.33 11.5 0.1 2.5 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 TPR_2 PF07719.17 PVD19303.1 - 0.0028 17.6 1.0 0.0092 16.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19303.1 - 0.012 15.4 0.5 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD19303.1 - 0.15 11.8 0.2 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 TPR repeat FAM60A PF15396.6 PVD19303.1 - 0.58 10.1 5.1 0.76 9.7 5.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Med27 PF11571.8 PVD19304.1 - 2.4e-27 95.1 0.1 1e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 27 Syntaxin-6_N PF09177.11 PVD19304.1 - 0.0029 18.1 0.5 0.0067 17.0 0.5 1.6 1 1 0 1 1 1 1 Syntaxin 6, N-terminal HMMR_N PF15905.5 PVD19304.1 - 0.1 12.0 1.5 0.14 11.6 1.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PDCD9 PF07147.12 PVD19305.1 - 2e-65 221.8 0.0 2.3e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) RNA_pol_Rpb1_5 PF04998.17 PVD19306.1 - 0.018 14.5 1.5 0.019 14.4 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 LRR_8 PF13855.6 PVD19307.1 - 1.4e-15 56.8 18.0 8.9e-11 41.4 4.3 4.8 5 1 0 5 5 5 3 Leucine rich repeat DNA_pol_A_exo1 PF01612.20 PVD19307.1 - 5.1e-10 39.3 0.0 1.5e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease TIR PF01582.20 PVD19307.1 - 5.3e-09 36.1 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD19307.1 - 1.9e-08 34.5 16.3 0.00041 20.7 1.0 5.5 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD19307.1 - 1.5e-07 32.0 0.0 3.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD19307.1 - 0.31 10.5 4.4 4.5 6.8 0.7 3.2 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 PVD19307.1 - 0.47 10.6 0.0 0.47 10.6 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 PVD19308.1 - 2.4e-18 65.6 28.6 1.6e-09 37.4 3.1 6.0 4 2 1 5 5 5 4 Leucine rich repeat TIR PF01582.20 PVD19308.1 - 2.3e-17 63.4 0.0 5.3e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD19308.1 - 7.3e-17 62.1 0.2 2.7e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 PVD19308.1 - 1e-06 28.4 6.0 0.0033 16.9 0.0 3.6 2 1 0 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 PVD19308.1 - 0.00076 19.8 28.8 0.24 11.9 6.3 6.2 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD19308.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.9 2 1 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) DUF1863 PF08937.11 PVD19308.1 - 0.15 12.3 0.1 1 9.7 0.1 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) SLC12 PF03522.15 PVD19309.1 - 2.4e-146 488.1 0.9 2.1e-144 481.7 0.9 2.1 1 1 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 PVD19309.1 - 5e-114 381.5 42.1 1.2e-113 380.2 42.1 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 PVD19309.1 - 1.4e-07 30.9 0.0 3.9e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Amino acid permease N-terminal HEAT PF02985.22 PVD19310.1 - 6.6e-07 29.1 0.1 0.23 11.8 0.0 3.4 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 PVD19310.1 - 9e-05 22.8 0.0 0.0003 21.1 0.0 1.8 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 PVD19310.1 - 0.00037 20.6 0.0 0.00077 19.5 0.0 1.5 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PVD19310.1 - 0.016 13.7 0.0 0.096 11.2 0.0 1.7 1 1 1 2 2 2 0 Adaptin N terminal region V-ATPase_H_C PF11698.8 PVD19310.1 - 0.024 14.8 0.0 4.6 7.4 0.0 2.8 2 1 1 3 3 3 0 V-ATPase subunit H DUF3437 PF11919.8 PVD19310.1 - 0.029 14.3 0.0 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 PVD19310.1 - 0.17 12.5 0.1 0.85 10.3 0.1 2.0 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region 7tm_1 PF00001.21 PVD19312.1 - 2.1e-13 50.2 8.3 8.2e-11 41.7 3.8 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19312.1 - 0.00054 19.7 8.1 0.00085 19.0 4.9 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD19316.1 - 0.0061 15.9 0.2 0.0078 15.6 0.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD19317.1 - 9.5e-22 77.6 19.7 9.5e-22 77.6 19.7 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_3 PF07859.13 PVD19318.1 - 3.7e-44 151.1 0.1 7.6e-44 150.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD19318.1 - 8.9e-09 34.7 0.1 7.6e-08 31.7 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 PVD19318.1 - 2.8e-06 26.5 0.1 6.6e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 PVD19318.1 - 0.00054 19.0 0.0 0.0012 17.8 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 PVD19318.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 PVD19318.1 - 0.003 16.6 0.1 0.0084 15.2 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase ATP-synt_D PF01813.17 PVD19318.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit D AXE1 PF05448.12 PVD19318.1 - 0.013 14.2 0.0 0.46 9.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 PVD19318.1 - 0.099 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase LapA_dom PF06305.11 PVD19318.1 - 0.16 11.8 0.9 0.34 10.7 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain 7tm_1 PF00001.21 PVD19319.1 - 2.5e-20 72.9 11.7 3.2e-20 72.5 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0242 PF06785.11 PVD19319.1 - 0.14 12.2 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 7tm_1 PF00001.21 PVD19320.1 - 6.9e-18 64.9 4.2 1.1e-17 64.3 4.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD19320.1 - 0.0014 18.1 2.0 0.0022 17.4 2.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD19320.1 - 0.005 16.2 1.9 0.0062 15.9 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3087 PF11286.8 PVD19320.1 - 0.068 12.6 1.3 0.094 12.2 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) DUF2070 PF09843.9 PVD19320.1 - 0.13 10.5 5.8 0.34 9.2 5.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Polysacc_deac_1 PF01522.21 PVD19321.1 - 2.4e-05 24.2 0.1 6.4e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 PVD19322.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 PVD19323.1 - 0.00053 19.9 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2194 PF09960.9 PVD19323.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF2334 PF10096.9 PVD19323.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) HTH_Tnp_4 PF13613.6 PVD19324.1 - 2.4e-05 24.0 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease ADIP PF11559.8 PVD19324.1 - 0.008 16.3 0.7 0.011 15.9 0.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Paralemmin PF03285.15 PVD19324.1 - 0.057 13.0 2.0 0.068 12.7 2.0 1.1 1 0 0 1 1 1 0 Paralemmin zf-MYND PF01753.18 PVD19325.1 - 0.002 18.2 3.0 0.002 18.2 3.0 1.9 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 PVD19325.1 - 0.018 16.2 0.3 0.041 15.0 0.3 1.6 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins TcpE PF12648.7 PVD19325.1 - 0.13 12.8 0.1 0.74 10.4 0.0 2.1 2 0 0 2 2 2 0 TcpE family FA_hydroxylase PF04116.13 PVD19326.1 - 2.3e-19 70.1 22.3 2.3e-19 70.1 22.3 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Cu2_monoox_C PF03712.15 PVD19327.1 - 3.3e-34 117.7 0.0 4.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD19327.1 - 4.2e-07 30.3 0.1 7.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain BTB PF00651.31 PVD19328.1 - 0.0099 16.1 0.2 0.021 15.1 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 PVD19329.1 - 1.4e-11 44.6 0.0 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain 7tm_1 PF00001.21 PVD19330.1 - 8.9e-18 64.5 12.5 8.9e-18 64.5 12.5 2.0 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19330.1 - 0.00043 20.0 7.1 0.00043 20.0 7.1 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx STE3 PF02076.15 PVD19330.1 - 0.00069 18.9 3.3 0.00069 18.9 3.3 3.4 2 1 0 4 4 4 1 Pheromone A receptor Abhydrolase_9_N PF15420.6 PVD19330.1 - 0.12 12.3 4.8 1 9.3 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus YtpI PF14007.6 PVD19330.1 - 0.17 12.1 4.6 0.76 10.0 0.6 3.3 3 0 0 3 3 3 0 YtpI-like protein Myosin_head PF00063.21 PVD19332.1 - 1.3e-228 760.6 12.0 6.7e-196 652.5 7.1 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.27 PVD19332.1 - 7e-45 152.6 0.0 3.8e-44 150.2 0.0 2.4 1 0 0 1 1 1 1 RhoGAP domain IQ PF00612.27 PVD19332.1 - 6.1e-11 41.1 29.6 0.00067 19.2 4.2 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif RA PF00788.23 PVD19332.1 - 6.8e-08 33.0 0.0 2.6e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 PVD19332.1 - 1.6e-06 27.9 10.6 3.2e-06 26.9 10.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_16 PF13191.6 PVD19332.1 - 0.0033 17.8 3.8 0.0055 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PVD19332.1 - 0.004 17.4 0.1 0.016 15.5 0.1 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD19332.1 - 0.018 14.1 1.0 0.057 12.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Arc_PepC PF06819.11 PVD19332.1 - 0.067 13.3 0.9 0.55 10.4 0.1 2.6 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain 7tm_2 PF00002.24 PVD19333.1 - 4.6e-12 45.8 13.7 6.1e-12 45.3 13.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 PVD19333.1 - 2e-11 43.6 9.0 2.6e-11 43.2 9.0 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 PVD19333.1 - 8.2e-08 31.9 10.7 1.2e-07 31.3 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD19333.1 - 0.00021 20.8 2.9 0.00029 20.3 2.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Perilipin PF03036.16 PVD19334.1 - 1.9e-34 119.3 0.4 2.6e-34 118.9 0.4 1.1 1 0 0 1 1 1 1 Perilipin family Spatacsin_C PF14649.6 PVD19335.1 - 5.5e-91 304.8 5.6 1e-90 303.9 3.3 2.2 2 0 0 2 2 2 1 Spatacsin C-terminus DUF4910 PF16254.5 PVD19335.1 - 0.1 11.4 0.1 0.25 10.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Vps39_1 PF10366.9 PVD19335.1 - 0.27 11.5 2.1 9.8 6.5 0.0 3.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 COR PF16095.5 PVD19336.1 - 1.3e-50 171.9 0.2 2e-49 168.1 0.1 2.5 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 PVD19336.1 - 1.3e-22 80.2 0.0 4.1e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 PVD19336.1 - 2.7e-17 62.3 20.4 3.7e-07 29.8 0.2 4.8 3 1 1 4 4 4 4 Leucine rich repeat TIR_2 PF13676.6 PVD19336.1 - 7.6e-16 58.8 0.1 3.4e-09 37.3 0.0 3.2 3 0 0 3 3 3 2 TIR domain Ras PF00071.22 PVD19336.1 - 3e-15 56.2 0.1 3.5e-13 49.5 0.0 2.5 2 0 0 2 2 2 1 Ras family LRR_4 PF12799.7 PVD19336.1 - 5.3e-10 39.4 28.4 0.0032 17.8 1.1 7.0 6 1 0 6 6 6 4 Leucine Rich repeats (2 copies) Arf PF00025.21 PVD19336.1 - 0.002 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD19336.1 - 0.0028 17.1 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_5 PF13306.6 PVD19336.1 - 0.0037 17.2 0.1 0.014 15.3 0.1 2.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) EF-hand_6 PF13405.6 PVD19336.1 - 0.0057 16.5 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain RsgA_GTPase PF03193.16 PVD19336.1 - 0.013 15.4 0.2 0.76 9.7 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 PVD19336.1 - 0.019 15.4 0.1 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_1 PF00036.32 PVD19336.1 - 0.022 14.3 0.1 0.23 11.1 0.0 2.7 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.6 PVD19336.1 - 0.042 14.0 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PVD19336.1 - 0.15 11.2 0.0 0.43 9.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RRM_1 PF00076.22 PVD19337.1 - 3.7e-35 119.6 0.2 3.1e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD19337.1 - 2.7e-13 49.8 0.2 7.8e-06 25.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD19337.1 - 0.002 18.1 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif adh_short PF00106.25 PVD19338.1 - 5.6e-29 101.0 5.9 4.7e-23 81.7 0.2 2.4 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19338.1 - 1.1e-19 71.0 1.4 1.6e-17 63.9 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF2532 PF10811.8 PVD19338.1 - 0.068 13.2 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2532) Myosin_head PF00063.21 PVD19339.1 - 2.2e-219 730.1 0.0 2.7e-219 729.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) SH2 PF00017.24 PVD19339.1 - 1.1e-17 63.9 0.1 2.7e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 SH2 domain IQ PF00612.27 PVD19339.1 - 3.5e-05 23.2 0.4 0.00013 21.4 0.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 PVD19339.1 - 0.0068 16.7 2.7 0.035 14.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PVD19339.1 - 0.032 14.6 4.7 0.046 14.1 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 PVD19339.1 - 0.12 12.9 0.7 0.59 10.7 0.3 2.5 2 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 PVD19339.1 - 0.18 11.8 0.3 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DFF-C PF09033.10 PVD19339.1 - 0.23 11.4 1.1 0.45 10.4 1.1 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Ig_3 PF13927.6 PVD19344.1 - 2.8e-26 91.9 1.2 3.6e-10 40.3 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD19344.1 - 1.7e-24 85.7 0.4 6.4e-09 35.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD19344.1 - 5.5e-20 71.3 0.4 4.8e-06 26.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD19344.1 - 1.9e-16 60.1 0.4 1.8e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD19344.1 - 3.5e-11 43.3 0.7 0.0026 17.9 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD19344.1 - 2.9e-05 23.5 0.1 0.04 13.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19344.1 - 0.0014 18.6 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Pox_C7_F8A PF03287.14 PVD19344.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus C7/F8A protein C2-set_2 PF08205.12 PVD19344.1 - 0.14 12.3 2.8 1.2 9.3 0.1 3.0 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain DUF3439 PF11921.8 PVD19344.1 - 7.9 6.5 9.5 4.4 7.3 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sec1 PF00995.23 PVD19345.1 - 1.3e-83 282.2 1.5 5.9e-82 276.7 0.2 2.0 1 1 1 2 2 2 2 Sec1 family SK_channel PF03530.14 PVD19346.1 - 1.1e-43 147.8 0.5 1.1e-43 147.8 0.5 2.3 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 PVD19346.1 - 2.5e-36 123.7 7.1 2.5e-36 123.7 7.1 2.2 2 0 0 2 2 2 1 Calmodulin binding domain Ion_trans_2 PF07885.16 PVD19346.1 - 2.1e-16 59.7 0.7 2.1e-16 59.7 0.7 2.3 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 PVD19346.1 - 0.00011 21.6 11.2 0.0028 16.9 11.2 2.3 1 1 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 PVD19346.1 - 0.028 14.3 0.2 0.065 13.1 0.1 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel DUF1664 PF07889.12 PVD19346.1 - 0.9 9.6 7.0 1.7 8.7 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 PVD19346.1 - 1.4 9.0 12.1 0.067 13.3 6.1 1.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HEAT PF02985.22 PVD19348.1 - 0.0016 18.5 0.1 1.5 9.3 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 PVD19348.1 - 0.018 15.4 0.0 0.039 14.4 0.0 1.5 2 0 0 2 2 2 0 HEAT repeats Cnd1 PF12717.7 PVD19348.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 zf-RING_UBOX PF13445.6 PVD19349.1 - 1.3e-08 34.7 4.4 1.3e-08 34.7 4.4 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 PVD19349.1 - 1.6e-07 31.4 9.7 1.6e-07 31.4 9.7 2.6 3 0 0 3 3 1 1 B-box zinc finger zf-RING_5 PF14634.6 PVD19349.1 - 5.1e-07 29.6 7.8 5.1e-07 29.6 7.8 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD19349.1 - 9e-05 22.7 12.9 9e-05 22.7 12.9 3.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PVD19349.1 - 0.00065 19.5 9.9 0.00065 19.5 9.9 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Syntaxin-6_N PF09177.11 PVD19349.1 - 0.0012 19.4 2.4 0.0012 19.4 2.4 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Spc7 PF08317.11 PVD19349.1 - 0.0027 16.7 3.5 0.0027 16.7 3.5 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein zf-C3HC4_2 PF13923.6 PVD19349.1 - 0.0027 17.5 6.7 0.0027 17.5 6.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HIP1_clath_bdg PF16515.5 PVD19349.1 - 0.024 15.3 5.8 0.024 15.3 5.8 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2959 PF11172.8 PVD19349.1 - 0.04 14.1 2.3 0.11 12.7 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Vps54 PF07928.12 PVD19349.1 - 0.083 13.3 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Vps54-like protein CorA PF01544.18 PVD19349.1 - 0.17 11.2 4.6 0.28 10.4 4.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF148 PF02520.17 PVD19349.1 - 0.48 10.5 6.4 0.12 12.5 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 DUF16 PF01519.16 PVD19349.1 - 0.61 10.6 0.0 0.61 10.6 0.0 2.7 3 1 0 3 3 2 0 Protein of unknown function DUF16 Defensin_propep PF00879.18 PVD19349.1 - 0.79 10.0 5.5 1.9 8.8 0.1 3.0 3 0 0 3 3 3 0 Defensin propeptide NPV_P10 PF05531.12 PVD19349.1 - 0.91 10.0 7.3 5.8 7.4 0.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 PVD19349.1 - 1.2 9.2 10.5 0.81 9.8 6.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Exonuc_VII_L PF02601.15 PVD19349.1 - 1.8 8.0 8.3 0.3 10.6 3.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2616 PF11077.8 PVD19349.1 - 2.6 7.7 10.0 2.1 8.0 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) SKA2 PF16740.5 PVD19349.1 - 3.1 7.6 8.0 1.6 8.6 0.5 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 PVD19349.1 - 3.8 7.6 7.6 0.58 10.2 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 PVD19349.1 - 5.5 6.1 6.0 0.72 9.0 0.6 2.1 2 1 1 3 3 3 0 TMPIT-like protein YqjK PF13997.6 PVD19349.1 - 8.5 6.7 7.0 15 5.9 1.0 2.5 2 0 0 2 2 2 0 YqjK-like protein Arrestin_N PF00339.29 PVD19350.1 - 9.9e-36 123.0 0.1 4.2e-34 117.7 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD19350.1 - 2.2e-12 47.6 0.0 1.7e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD19350.1 - 0.0023 17.2 0.0 0.0062 15.8 0.0 1.6 2 0 0 2 2 2 1 Rgp1 LDB19 PF13002.7 PVD19350.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like ubiquitin PF00240.23 PVD19351.1 - 5.8e-19 67.6 0.3 1e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 PVD19351.1 - 1.3e-10 41.1 57.0 0.0024 17.8 8.9 6.9 4 2 3 7 7 7 6 STI1 domain Rad60-SLD PF11976.8 PVD19351.1 - 5.7e-07 29.3 0.1 9.7e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PVD19351.1 - 0.00037 20.8 0.1 0.00082 19.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 PVD19351.1 - 0.0015 19.2 0.0 0.0042 17.7 0.0 1.8 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.6 PVD19351.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 PVD19351.1 - 0.035 14.1 0.0 2.5 8.2 0.0 2.4 1 1 0 1 1 1 0 Ubiquitin-like domain UCH PF00443.29 PVD19351.1 - 0.16 11.5 1.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF2407 PF10302.9 PVD19351.1 - 0.19 12.3 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Spc7 PF08317.11 PVD19351.1 - 1.2 8.0 4.4 1.7 7.4 3.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein ComX PF05952.12 PVD19351.1 - 3.1 7.8 8.9 95 3.0 0.0 5.4 5 1 1 6 6 6 0 Bacillus competence pheromone ComX DUF1400 PF07176.11 PVD19351.1 - 6.6 7.0 7.1 19 5.6 0.2 3.1 3 1 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) SCAPER_N PF16501.5 PVD19352.1 - 2.4e-31 107.7 0.1 1.1e-30 105.6 0.1 2.2 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 PVD19352.1 - 1.8e-06 28.2 0.1 4.3e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD19352.1 - 0.0014 18.9 0.0 0.0036 17.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding LIM PF00412.22 PVD19357.1 - 3.3e-09 36.9 3.8 5.1e-09 36.2 3.8 1.3 1 0 0 1 1 1 1 LIM domain CBM_14 PF01607.24 PVD19358.1 - 4e-36 123.0 62.0 1e-10 41.6 1.6 7.3 6 1 1 7 7 7 7 Chitin binding Peritrophin-A domain ATG16 PF08614.11 PVD19360.1 - 0.0034 17.6 19.3 0.0034 17.6 19.3 15.2 1 1 10 13 13 13 2 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 PVD19360.1 - 0.013 15.9 2.9 0.013 15.9 2.9 19.1 20 3 1 21 21 21 0 Flagella accessory protein C (FlaC) Gly-rich_Ago1 PF12764.7 PVD19361.1 - 1.2 9.9 7.1 0.16 12.7 1.4 2.0 1 1 0 2 2 2 0 Glycine-rich region of argonaut Homeodomain PF00046.29 PVD19363.1 - 9.8e-15 54.1 1.5 1.9e-14 53.2 1.5 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 PVD19364.1 - 1.4e-06 27.9 1.2 1.4e-06 27.9 1.2 1.7 2 0 0 2 2 2 1 OAR domain Homeodomain PF00046.29 PVD19365.1 - 4.6e-24 84.0 4.6 7.6e-24 83.3 4.6 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 PVD19365.1 - 1.3e-07 31.2 1.5 2.8e-07 30.1 1.5 1.6 1 0 0 1 1 1 1 OAR domain Cyclin_C PF02984.19 PVD19366.1 - 0.00028 20.9 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain TSP_C PF05735.12 PVD19367.1 - 1.7e-94 315.3 0.7 2.3e-94 314.9 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 PVD19367.1 - 4.5e-57 189.4 145.4 2.5e-12 46.2 17.3 9.8 7 2 1 8 8 8 7 Thrombospondin type 3 repeat EGF_CA PF07645.15 PVD19367.1 - 2e-13 50.3 63.9 3.5e-07 30.3 1.7 6.0 4 1 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 PVD19367.1 - 1.4e-12 47.2 56.4 4.6e-06 26.5 0.3 7.2 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD19367.1 - 3.2e-11 43.2 69.0 0.00016 21.8 10.4 6.5 6 0 0 6 6 6 4 EGF domain COMP PF11598.8 PVD19367.1 - 5.5e-08 33.2 2.2 1.3e-07 32.0 2.2 1.6 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF PF00008.27 PVD19367.1 - 0.00047 20.4 79.7 0.045 14.1 7.0 6.9 6 0 0 6 6 6 4 EGF-like domain TFR_dimer PF04253.15 PVD19368.1 - 8.4e-57 190.5 0.3 2e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 PVD19368.1 - 1.4e-36 126.1 0.0 1.4e-18 67.3 0.0 3.0 3 0 0 3 3 3 2 Peptidase family M28 PA PF02225.22 PVD19368.1 - 9.2e-25 86.5 0.0 1.5e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 PA domain Peptidase_M20 PF01546.28 PVD19368.1 - 5.2e-06 26.3 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 DUF3486 PF11985.8 PVD19368.1 - 0.0006 20.3 0.2 1.1 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3486) Nicastrin PF05450.15 PVD19368.1 - 0.0022 17.5 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 Nicastrin BRO1 PF03097.18 PVD19368.1 - 0.027 13.3 1.1 1.5 7.6 0.2 2.3 2 0 0 2 2 2 0 BRO1-like domain T7SS_ESX_EspC PF10824.8 PVD19368.1 - 0.085 13.3 1.5 0.75 10.3 0.2 2.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Prismane PF03063.20 PVD19368.1 - 0.22 10.2 0.1 10 4.7 0.0 2.1 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family TFR_dimer PF04253.15 PVD19369.1 - 5.1e-27 94.4 0.0 9.9e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 PVD19369.1 - 1.3e-19 70.6 0.0 2.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD19369.1 - 0.0005 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 PVD19369.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.15 PVD19370.1 - 5.5e-29 100.7 0.0 9.9e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 PVD19370.1 - 1.7e-19 70.3 0.0 3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD19370.1 - 1.5e-11 44.2 0.0 2.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 PVD19370.1 - 0.063 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Nicastrin Rad9 PF04139.13 PVD19370.1 - 0.08 12.4 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Rad9 Peptidase_M20 PF01546.28 PVD19370.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 7tm_1 PF00001.21 PVD19371.1 - 9.7e-10 38.2 0.8 9.7e-10 38.2 0.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) TMPIT PF07851.13 PVD19371.1 - 0.057 12.7 0.3 0.09 12.0 0.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein MARVEL PF01284.23 PVD19371.1 - 0.095 12.7 3.6 0.17 11.9 3.6 1.3 1 1 0 1 1 1 0 Membrane-associating domain 7tm_1 PF00001.21 PVD19374.1 - 8.1e-20 71.2 0.2 1.1e-19 70.8 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.6 PVD19374.1 - 0.28 11.5 5.5 0.23 11.8 0.6 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_1 PF00001.21 PVD19376.1 - 9.4e-08 31.7 16.0 5.1e-07 29.3 16.0 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Otopetrin PF03189.13 PVD19376.1 - 4.4 6.0 8.9 0.26 10.0 2.2 2.0 2 0 0 2 2 2 0 Otopetrin CENP-H PF05837.12 PVD19377.1 - 1.1e-21 77.4 8.3 1.6e-21 76.8 3.3 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Phage_GP20 PF06810.11 PVD19377.1 - 0.0019 18.0 8.7 0.024 14.4 0.3 2.4 2 1 0 2 2 2 1 Phage minor structural protein GP20 RasGAP_C PF03836.15 PVD19377.1 - 0.0024 18.0 2.4 0.0024 18.0 2.4 1.9 2 0 0 2 2 2 1 RasGAP C-terminus Ribosomal_L29 PF00831.23 PVD19377.1 - 0.0054 16.7 8.2 0.16 12.0 0.5 2.9 2 0 0 2 2 2 1 Ribosomal L29 protein Mod_r PF07200.13 PVD19377.1 - 0.015 15.4 3.9 0.015 15.4 3.9 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IMD PF08397.11 PVD19377.1 - 0.02 14.3 4.4 0.021 14.2 3.3 1.6 1 1 0 1 1 1 0 IRSp53/MIM homology domain Csm1_N PF18504.1 PVD19377.1 - 0.02 15.2 3.8 0.02 15.2 3.8 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain Prominin PF05478.11 PVD19377.1 - 0.026 12.5 4.6 0.015 13.3 2.6 1.5 1 1 0 1 1 1 0 Prominin CorA PF01544.18 PVD19377.1 - 0.027 13.8 4.9 0.031 13.6 4.3 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Phasin PF05597.11 PVD19377.1 - 0.031 14.3 7.1 1.5 8.8 1.1 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) bZIP_1 PF00170.21 PVD19377.1 - 0.034 14.2 5.6 0.034 14.2 5.6 3.0 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 PVD19377.1 - 0.039 14.6 7.3 0.067 13.8 3.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 PVD19377.1 - 0.051 12.9 1.4 0.075 12.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD19377.1 - 0.056 13.0 3.5 0.073 12.6 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1192 PF06698.11 PVD19377.1 - 0.06 13.4 5.4 0.14 12.2 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) KxDL PF10241.9 PVD19377.1 - 0.065 13.5 10.1 4.5 7.6 0.3 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF4482 PF14818.6 PVD19377.1 - 0.067 14.1 9.9 1.7 9.5 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) WEMBL PF05701.11 PVD19377.1 - 0.17 10.5 11.4 0.23 10.1 11.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.12 PVD19377.1 - 0.21 12.1 4.6 10 6.7 0.5 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 PVD19377.1 - 0.26 11.8 13.1 4.8 7.7 8.0 2.8 2 1 0 2 2 2 0 Cell division protein ZapB KLRAQ PF10205.9 PVD19377.1 - 0.28 11.5 9.7 0.78 10.0 3.8 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TSC22 PF01166.18 PVD19377.1 - 0.3 11.4 11.6 2.8 8.3 2.6 3.4 3 1 0 3 3 3 0 TSC-22/dip/bun family Cob_adeno_trans PF01923.18 PVD19377.1 - 0.34 11.0 3.8 7.9 6.6 0.4 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TMPIT PF07851.13 PVD19377.1 - 0.4 9.9 6.0 0.13 11.5 1.9 1.9 2 0 0 2 2 2 0 TMPIT-like protein DUF4140 PF13600.6 PVD19377.1 - 0.57 10.7 10.0 0.56 10.7 1.4 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cnn_1N PF07989.11 PVD19377.1 - 0.63 10.2 14.2 1.3 9.2 4.1 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4094 PF13334.6 PVD19377.1 - 0.65 10.5 4.1 4.7 7.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4665 PF15679.5 PVD19377.1 - 0.66 10.6 7.0 7.1 7.3 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) DUF4201 PF13870.6 PVD19377.1 - 0.75 9.5 14.8 2.1 8.0 5.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) PRKG1_interact PF15898.5 PVD19377.1 - 0.79 10.6 14.8 4.8 8.2 8.6 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Calici_MSP PF05752.11 PVD19377.1 - 0.82 9.5 4.4 1.3 8.8 0.3 2.3 2 1 0 2 2 2 0 Calicivirus minor structural protein TPR_MLP1_2 PF07926.12 PVD19377.1 - 0.87 9.7 11.0 2.1 8.4 6.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 PVD19377.1 - 0.94 9.5 17.6 0.53 10.3 7.3 2.6 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 PVD19377.1 - 1 9.7 10.9 3.4 8.0 0.4 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain Mis14 PF08641.12 PVD19377.1 - 1.1 9.5 8.0 3.8 7.8 0.5 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Spc7 PF08317.11 PVD19377.1 - 1.6 7.6 13.5 1.3 7.8 6.1 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein CP12 PF02672.15 PVD19377.1 - 1.6 9.6 4.4 15 6.4 0.2 3.0 3 0 0 3 3 3 0 CP12 domain FlaC_arch PF05377.11 PVD19377.1 - 1.7 9.1 8.8 3.1 8.3 1.3 3.4 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 PVD19377.1 - 2 8.6 16.7 0.22 11.7 1.4 2.4 2 1 0 2 2 2 0 Tropomyosin like Pox_A_type_inc PF04508.12 PVD19377.1 - 2 8.4 10.5 1.6 8.7 2.9 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DivIC PF04977.15 PVD19377.1 - 2.3 8.0 11.9 1.7 8.5 3.1 2.7 2 1 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 PVD19377.1 - 2.5 8.1 9.9 1.5 8.9 1.1 2.5 2 1 0 2 2 2 0 FlxA-like protein Fzo_mitofusin PF04799.13 PVD19377.1 - 2.8 7.5 6.2 1 8.9 1.7 2.3 1 1 1 2 2 2 0 fzo-like conserved region GrpE PF01025.19 PVD19377.1 - 3 7.5 12.1 4.7 6.8 3.9 2.2 1 1 1 2 2 2 0 GrpE DUF4709 PF15821.5 PVD19377.1 - 3.2 8.1 8.7 0.46 10.8 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) SlyX PF04102.12 PVD19377.1 - 3.8 8.2 11.3 4.4 8.0 1.9 2.9 3 1 0 3 3 2 0 SlyX DUF2205 PF10224.9 PVD19377.1 - 4.1 7.5 11.8 6.8 6.8 0.5 2.6 2 1 0 2 2 2 0 Short coiled-coil protein Fib_alpha PF08702.10 PVD19377.1 - 4.3 7.5 8.7 4.9 7.3 2.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HalX PF08663.10 PVD19377.1 - 4.6 7.6 15.6 1.5 9.2 2.7 3.3 4 1 0 4 4 2 0 HalX domain Atg14 PF10186.9 PVD19377.1 - 5 6.1 12.3 0.73 8.9 5.6 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT_CC PF16559.5 PVD19377.1 - 6.8 6.6 8.9 26 4.8 2.7 3.1 3 1 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-ribbon_3 PF13248.6 PVD19378.1 - 0.03 13.7 0.1 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RVT_1 PF00078.27 PVD19379.1 - 2.4e-21 76.3 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Beta-lactamase PF00144.24 PVD19380.1 - 1.4e-45 156.0 0.2 2.1e-45 155.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 PVD19380.1 - 0.00019 21.8 0.0 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.24 PVD19381.1 - 1.4e-41 142.8 0.2 2.3e-41 142.1 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Plus-3 PF03126.18 PVD19381.1 - 0.0081 16.7 0.0 0.51 10.9 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain DUF3471 PF11954.8 PVD19381.1 - 0.03 14.8 0.1 0.069 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Ig_3 PF13927.6 PVD19382.1 - 5.2e-22 78.2 1.2 3.5e-10 40.3 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19382.1 - 4.4e-20 71.5 0.2 1.3e-10 41.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD19382.1 - 2.2e-17 63.2 0.5 4.4e-09 36.5 0.1 2.9 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD19382.1 - 1.8e-16 60.1 0.3 9.9e-09 35.3 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19382.1 - 2.9e-13 50.0 0.8 4.2e-06 27.0 0.2 3.0 2 2 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD19382.1 - 5.5e-09 35.5 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 PVD19382.1 - 4.7e-05 23.7 0.7 0.26 11.7 0.1 3.5 2 2 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD19382.1 - 0.016 15.2 0.1 0.6 10.2 0.0 2.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain I-set PF07679.16 PVD19386.1 - 1.4e-17 63.5 0.0 8.1e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19386.1 - 6.1e-14 52.4 0.3 6e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19386.1 - 9.8e-11 41.8 0.2 2.4e-05 24.6 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD19386.1 - 1.6e-09 37.8 0.1 0.0025 17.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19386.1 - 3.7e-08 33.5 0.3 0.00027 21.1 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD19386.1 - 7.6e-06 25.9 0.1 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD19386.1 - 0.012 15.8 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Ca_hom_mod PF14798.6 PVD19389.1 - 8.2e-08 31.7 9.4 1.6e-07 30.7 3.2 2.7 2 1 1 3 3 3 2 Calcium homeostasis modulator TIR_2 PF13676.6 PVD19390.1 - 1.8e-17 64.0 0.0 6.1e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 TIR domain Death PF00531.22 PVD19390.1 - 2.2e-05 24.5 0.1 0.00026 21.1 0.0 2.9 2 0 0 2 2 2 1 Death domain HEAT_EZ PF13513.6 PVD19390.1 - 0.00076 19.9 0.0 1.1 9.8 0.0 4.3 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 PVD19390.1 - 0.026 13.1 0.5 0.14 10.7 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region DUF489 PF04356.12 PVD19390.1 - 0.16 12.0 0.1 0.45 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF489) TIR_2 PF13676.6 PVD19392.1 - 3.5e-46 156.7 0.0 2.1e-21 76.7 0.0 3.2 3 0 0 3 3 3 2 TIR domain Death PF00531.22 PVD19392.1 - 1.9e-11 44.0 0.4 5e-11 42.6 0.4 1.8 1 0 0 1 1 1 1 Death domain TIR PF01582.20 PVD19392.1 - 2.8e-09 37.0 0.1 0.0017 18.2 0.0 3.7 4 0 0 4 4 4 2 TIR domain DUF16 PF01519.16 PVD19392.1 - 0.017 15.6 0.7 0.049 14.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 PVD19392.1 - 0.045 13.8 2.8 0.14 12.2 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Aldedh PF00171.22 PVD19394.1 - 5.2e-153 509.9 0.0 7.2e-153 509.4 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RCC1 PF00415.18 PVD19395.1 - 1e-139 455.1 54.8 6.3e-13 49.1 0.3 14.9 14 0 0 14 14 14 14 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD19395.1 - 3.6e-62 205.1 89.6 4.6e-09 35.8 1.1 15.8 16 0 0 16 16 16 12 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 PVD19395.1 - 4e-41 141.5 0.0 6.7e-25 88.2 0.1 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 PVD19395.1 - 6e-13 49.0 0.0 1.7e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.32 PVD19395.1 - 2e-11 44.2 10.6 0.002 18.9 0.1 7.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD19395.1 - 1.2e-09 38.3 1.6 0.0018 18.5 0.0 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Neurokinin_B PF03823.14 PVD19395.1 - 3.7 7.7 6.0 35 4.5 0.1 4.1 4 0 0 4 4 4 0 Neurokinin B BTB_2 PF02214.22 PVD19396.1 - 2e-25 88.9 0.2 7.2e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF4797 PF16051.5 PVD19396.1 - 0.16 11.9 4.1 0.26 11.2 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Ion_trans PF00520.31 PVD19397.1 - 1.3e-24 86.8 17.3 1.7e-24 86.4 17.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD19397.1 - 1.1e-07 31.6 12.8 2.3e-07 30.7 12.8 1.5 1 0 0 1 1 1 1 Ion channel EF-hand_7 PF13499.6 PVD19398.1 - 3.6e-12 46.6 2.9 6.5e-10 39.3 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD19398.1 - 2.8e-10 39.0 3.4 0.0039 16.6 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD19398.1 - 3.4e-08 32.8 4.1 0.00078 19.2 0.1 3.5 2 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PVD19398.1 - 0.00014 21.7 8.6 0.00035 20.4 2.8 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD19398.1 - 0.00053 19.4 3.3 0.04 13.4 0.2 2.8 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD19398.1 - 0.08 13.3 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.8 PVD19398.1 - 0.15 12.9 0.1 0.27 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) TBX PF12598.8 PVD19399.1 - 0.19 12.5 0.3 0.19 12.5 0.3 1.8 2 0 0 2 2 2 0 T-box transcription factor CLN6 PF15156.6 PVD19401.1 - 3.5e-50 170.8 4.3 2.7e-29 102.3 2.7 2.0 2 0 0 2 2 2 2 Ceroid-lipofuscinosis neuronal protein 6 DUF1218 PF06749.12 PVD19401.1 - 0.047 14.2 0.1 0.91 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF751 PF05421.11 PVD19401.1 - 0.26 12.0 2.4 2.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF751) FAM219A PF15260.6 PVD19402.1 - 1.5e-18 67.3 5.9 1.5e-18 67.3 5.9 1.7 1 1 0 1 1 1 1 Protein family FAM219A Lig_chan-Glu_bd PF10613.9 PVD19403.1 - 1.9e-20 73.2 0.0 3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD19403.1 - 7.4e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 cNMP_binding PF00027.29 PVD19404.1 - 1.8e-19 69.6 0.0 3.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD19404.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PVD19404.1 - 0.014 14.7 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein Ion_trans_N PF08412.10 PVD19405.1 - 8.5e-25 86.1 0.2 1.5e-24 85.3 0.2 1.4 1 0 0 1 1 1 1 Ion transport protein N-terminal Ank_2 PF12796.7 PVD19406.1 - 1.9e-26 92.5 4.6 1.9e-12 47.6 0.3 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD19406.1 - 2e-21 76.0 6.9 6.4e-05 23.4 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD19406.1 - 6.7e-20 70.6 14.5 2.9e-05 24.3 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 PVD19406.1 - 1e-17 62.4 8.9 9.4e-05 22.5 0.0 8.4 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 PVD19406.1 - 1.2e-11 44.6 9.5 0.0055 17.0 0.0 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) HIT PF01230.23 PVD19406.1 - 0.12 13.1 0.0 2.7 8.8 0.0 2.4 2 0 0 2 2 2 0 HIT domain Pentapeptide_4 PF13599.6 PVD19407.1 - 1.3e-51 172.7 60.6 7.7e-05 22.8 0.2 14.4 1 1 12 13 13 13 13 Pentapeptide repeats (9 copies) Com_YlbF PF06133.11 PVD19407.1 - 2.2 8.9 30.6 9.1 6.9 3.0 5.6 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA AMP-binding PF00501.28 PVD19408.1 - 1.4e-91 307.2 0.0 1.8e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 PVD19408.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Membr_traf_MHD PF10540.9 PVD19411.1 - 1.6e-49 167.9 2.6 4.7e-49 166.4 2.6 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 PVD19411.1 - 1.8e-43 147.0 4.4 1.9e-26 92.4 0.2 4.0 4 0 0 4 4 4 2 C2 domain DUF1041 PF06292.17 PVD19411.1 - 4.3e-34 117.1 5.6 1.9e-33 115.0 0.6 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 PVD19411.1 - 2e-11 43.6 6.0 4.6e-11 42.4 6.0 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SRI PF08236.11 PVD19411.1 - 0.025 14.8 0.1 17 5.7 0.0 3.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Bcr-Abl_Oligo PF09036.10 PVD19411.1 - 0.032 14.2 0.0 0.84 9.7 0.0 2.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DDA1 PF10172.9 PVD19412.1 - 1.8e-29 101.8 0.4 2.6e-29 101.3 0.4 1.2 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase PCI PF01399.27 PVD19413.1 - 9.2e-26 90.4 1.5 9.2e-26 90.4 1.5 3.1 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.6 PVD19413.1 - 6.3e-08 32.1 5.2 2 8.7 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19413.1 - 0.00062 19.5 6.9 1.5 8.7 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF4704 PF15787.5 PVD19413.1 - 0.0013 18.1 0.7 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) TPR_14 PF13428.6 PVD19413.1 - 0.0049 17.6 0.2 33 5.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19413.1 - 0.0091 16.0 6.9 8.6 6.8 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Bac_rhamnosid6H PF17389.2 PVD19413.1 - 0.32 10.2 2.8 1.1 8.5 2.9 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain TPR_6 PF13174.6 PVD19413.1 - 0.42 11.4 3.6 1.1e+02 3.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19413.1 - 1.7 9.0 13.1 53 4.4 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 PVD19414.1 - 1.3e-24 86.0 5.8 4.6e-05 24.1 0.4 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat DAO PF01266.24 PVD19414.1 - 9e-22 78.1 0.0 2.8e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase UTP15_C PF09384.10 PVD19414.1 - 1.9e-19 69.8 0.1 3.6e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 PVD19414.1 - 2e-07 31.2 0.0 0.13 12.5 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Metal_resist PF13801.6 PVD19415.1 - 0.02 15.1 0.3 0.022 15.0 0.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance YcbB PF08664.10 PVD19415.1 - 0.048 13.7 0.2 0.056 13.5 0.2 1.1 1 0 0 1 1 1 0 YcbB domain NusB PF01029.18 PVD19415.1 - 0.054 13.7 0.1 0.059 13.6 0.1 1.0 1 0 0 1 1 1 0 NusB family ARID PF01388.21 PVD19417.1 - 1.2e-12 48.3 0.1 1.8e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA_23 PF13476.6 PVD19418.1 - 1.8e-19 71.0 2.6 1.8e-19 71.0 2.6 5.8 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.19 PVD19418.1 - 5.2e-13 48.9 24.0 1.1e-11 44.6 24.0 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD19418.1 - 1.1e-07 32.0 1.0 0.0075 16.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PVD19418.1 - 3e-07 30.5 11.9 3e-07 30.5 11.9 3.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran_CTD PF16326.5 PVD19418.1 - 0.001 19.3 3.4 0.001 19.3 3.4 8.0 6 3 2 8 8 8 2 ABC transporter C-terminal domain AAA_25 PF13481.6 PVD19418.1 - 0.0032 17.1 0.1 0.0094 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PVD19418.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FUSC PF04632.12 PVD19418.1 - 0.3 9.6 21.4 0.12 10.9 7.7 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family KxDL PF10241.9 PVD19419.1 - 2e-27 95.3 3.3 3.3e-27 94.6 3.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein Ring_hydroxyl_A PF00848.19 PVD19419.1 - 0.0067 16.4 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Helo_like_N PF17111.5 PVD19419.1 - 0.015 14.7 1.0 0.022 14.1 1.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PRD PF00874.20 PVD19419.1 - 0.15 12.4 1.3 0.27 11.6 1.1 1.5 1 1 0 1 1 1 0 PRD domain EST1 PF10374.9 PVD19419.1 - 2.4 8.8 5.9 4.9 7.8 5.9 1.7 1 1 0 1 1 1 0 Telomerase activating protein Est1 AIG1 PF04548.16 PVD19421.1 - 5.4e-45 153.3 1.6 3.1e-44 150.8 0.1 2.0 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PVD19421.1 - 7.2e-10 39.0 0.3 3.1e-09 36.9 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD19421.1 - 2e-05 24.7 6.5 0.00052 20.1 0.5 3.0 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 PVD19421.1 - 3.1e-05 23.6 0.0 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 PVD19421.1 - 4.6e-05 22.9 0.1 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 PVD19421.1 - 5.4e-05 23.7 0.0 0.00013 22.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD19421.1 - 0.00015 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 PVD19421.1 - 0.00066 19.1 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Septin DUF87 PF01935.17 PVD19421.1 - 0.0016 18.5 3.5 0.023 14.8 0.1 2.5 2 1 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 PVD19421.1 - 0.0098 16.1 0.1 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 PVD19421.1 - 0.011 15.1 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 PVD19421.1 - 0.012 15.9 0.5 0.35 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PVD19421.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PVD19421.1 - 0.026 14.9 0.0 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PVD19421.1 - 0.039 14.3 0.7 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.12 PVD19421.1 - 0.051 12.9 0.3 0.094 12.1 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PVD19421.1 - 0.44 10.3 2.4 27 4.4 0.2 3.1 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 PVD19422.1 - 1.1e-90 302.6 3.0 4.6e-46 156.8 0.4 3.2 2 1 1 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 PVD19422.1 - 6.6e-21 74.5 0.1 4.4e-09 36.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD19422.1 - 9.3e-12 45.2 0.0 6.3e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PVD19422.1 - 5.6e-11 42.2 0.1 0.00012 21.6 0.0 2.8 3 0 0 3 3 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 PVD19422.1 - 6.1e-10 39.7 0.0 0.00046 20.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 PVD19422.1 - 2.2e-09 37.6 11.4 0.005 16.9 1.0 4.8 3 2 2 5 5 5 2 Dynamin family FtsK_SpoIIIE PF01580.18 PVD19422.1 - 2.8e-09 36.7 0.1 0.00023 20.6 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family Septin PF00735.18 PVD19422.1 - 1.2e-07 31.3 0.1 0.0037 16.6 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_7 PF12775.7 PVD19422.1 - 2.9e-07 30.2 0.2 0.0035 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region SRPRB PF09439.10 PVD19422.1 - 3.1e-07 30.0 0.0 0.0013 18.2 0.0 2.7 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PVD19422.1 - 8.4e-06 26.3 2.0 0.22 11.9 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 PVD19422.1 - 1.4e-05 25.3 5.9 0.011 15.9 0.5 3.7 3 1 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 PVD19422.1 - 2.8e-05 24.4 0.6 0.53 10.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain IIGP PF05049.13 PVD19422.1 - 4.6e-05 22.6 0.5 0.023 13.7 0.0 2.6 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 PVD19422.1 - 8e-05 21.8 0.1 0.34 9.9 0.2 2.8 2 1 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 PVD19422.1 - 0.00024 20.8 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Roc PF08477.13 PVD19422.1 - 0.00028 21.1 0.7 0.24 11.6 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 PVD19422.1 - 0.0013 19.1 0.0 0.88 10.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase SMC_N PF02463.19 PVD19422.1 - 0.0019 17.7 2.0 1 8.7 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 PVD19422.1 - 0.005 16.0 0.2 1.4 8.0 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit dNK PF01712.19 PVD19422.1 - 0.0051 16.7 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase Guanylate_kin PF00625.21 PVD19422.1 - 0.0053 16.5 0.1 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 Guanylate kinase Pox_A32 PF04665.12 PVD19422.1 - 0.0055 16.2 0.0 3.7 6.9 0.0 2.7 2 0 0 2 2 2 1 Poxvirus A32 protein Gtr1_RagA PF04670.12 PVD19422.1 - 0.0091 15.4 0.1 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PVD19422.1 - 0.014 15.2 0.1 9.7 5.9 0.0 3.9 4 1 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 PVD19422.1 - 0.021 14.6 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 PVD19422.1 - 0.025 14.2 0.1 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Ras family AAA_5 PF07728.14 PVD19422.1 - 0.027 14.5 0.3 12 5.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PVD19422.1 - 0.03 13.5 0.0 7.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 PVD19422.1 - 0.03 13.9 0.7 7.1 6.2 0.1 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 PVD19422.1 - 0.039 13.7 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 PVD19422.1 - 0.052 12.8 0.0 5.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 PVD19422.1 - 0.053 14.0 1.0 27 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 PVD19422.1 - 0.064 13.0 7.1 7.2 6.3 0.0 4.4 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein DUF2115 PF09888.9 PVD19422.1 - 0.068 13.7 0.4 9.3 6.7 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) FerI PF08151.12 PVD19422.1 - 0.071 13.2 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 FerI (NUC094) domain AAA_15 PF13175.6 PVD19422.1 - 0.17 11.6 1.0 7.9 6.1 0.5 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 PVD19422.1 - 0.18 12.0 1.0 18 5.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 PVD19422.1 - 0.19 11.5 0.3 12 5.6 0.0 3.0 3 1 0 3 3 2 0 DEAD/DEAH box helicase T-box_assoc PF16176.5 PVD19423.1 - 0.1 12.7 1.2 0.16 12.1 0.3 1.7 2 0 0 2 2 2 0 T-box transcription factor-associated Mito_fiss_reg PF05308.11 PVD19423.1 - 4 7.5 6.9 5.9 6.9 6.9 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD19423.1 - 4.2 6.8 5.8 3.5 7.0 5.1 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Hormone_recep PF00104.30 PVD19428.1 - 1.8e-36 125.7 0.0 2.3e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD19429.1 - 1.1e-30 105.9 16.3 1.6e-30 105.3 16.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Dicty_REP PF05086.12 PVD19431.1 - 0.12 10.3 7.7 0.14 10.1 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 PVD19431.1 - 0.22 9.7 15.6 0.29 9.3 15.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 PVD19431.1 - 0.83 7.7 8.1 1 7.3 8.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 PVD19431.1 - 9.9 6.1 24.9 8.6 6.4 23.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein RCC1 PF00415.18 PVD19434.1 - 2.5e-47 159.3 14.5 8.7e-14 51.9 0.7 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD19434.1 - 1.4e-31 107.6 21.1 7e-08 32.1 0.3 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 PVD19434.1 - 0.0044 17.2 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 Putative heavy-metal chelation Bac_rhamnosid_C PF17390.2 PVD19434.1 - 0.077 12.8 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Hira PF07569.11 PVD19434.1 - 0.13 11.9 0.0 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split RCC1 PF00415.18 PVD19435.1 - 8.5e-07 29.5 3.4 1.5e-06 28.7 3.4 1.4 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD19435.1 - 7.9e-05 22.3 7.9 0.068 13.0 1.0 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat ARF7EP_C PF14949.6 PVD19436.1 - 1.8e-32 112.1 8.2 1.8e-32 112.1 8.2 1.9 1 1 1 2 2 2 1 ARF7 effector protein C-terminus STAT_alpha PF01017.20 PVD19436.1 - 0.19 11.6 5.0 0.24 11.3 5.0 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain TMPIT PF07851.13 PVD19436.1 - 0.65 9.2 5.0 0.8 8.9 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S17e PF00833.18 PVD19437.1 - 9.8e-68 225.7 0.4 1.1e-67 225.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 GyrB_insert PF18053.1 PVD19437.1 - 0.053 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain RRM_1 PF00076.22 PVD19438.1 - 1.6e-47 159.2 0.3 6.8e-17 61.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD19438.1 - 4.9e-05 23.3 0.3 0.027 14.5 0.3 2.4 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 PVD19438.1 - 0.0053 16.8 0.0 2.1 8.5 0.1 2.7 2 0 0 2 2 2 2 Limkain b1 RRM_1 PF00076.22 PVD19439.1 - 3.6e-28 97.2 0.0 1.8e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD19439.1 - 0.0033 17.5 0.1 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 PVD19439.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JMY PF15871.5 PVD19440.1 - 6.7e-92 308.5 19.1 6.7e-92 308.5 19.1 1.9 2 0 0 2 2 2 1 Junction-mediating and -regulatory protein WHAMM-JMY_N PF15920.5 PVD19440.1 - 1.2e-16 60.3 0.2 3.2e-16 58.9 0.2 1.8 1 0 0 1 1 1 1 N-terminal of Junction-mediating and WASP homolog-associated Ion_trans PF00520.31 PVD19441.1 - 9.9e-233 768.3 107.3 1.7e-69 233.8 19.7 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 PVD19441.1 - 3.6e-11 42.4 93.2 9.1e-05 21.3 2.8 10.1 6 4 4 10 10 10 8 Polycystin cation channel GPHH PF16905.5 PVD19441.1 - 3.2e-06 26.8 0.0 7.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Herpes_BLLF1 PF05109.13 PVD19441.1 - 0.084 10.8 8.5 0.12 10.3 8.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) FliG_N PF14842.6 PVD19441.1 - 1.4 9.5 5.8 0.42 11.2 1.8 2.2 2 0 0 2 2 2 0 FliG N-terminal domain Ion_trans PF00520.31 PVD19442.1 - 1.7e-167 554.7 89.6 1e-53 182.1 20.0 5.3 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 PVD19442.1 - 4.8e-12 45.3 75.1 5.5e-05 22.0 9.2 8.1 4 4 4 8 8 8 7 Polycystin cation channel GPHH PF16905.5 PVD19442.1 - 1.5e-05 24.7 0.1 6.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated 7tm_1 PF00001.21 PVD19443.1 - 6.6e-06 25.6 13.8 2.3e-05 23.8 13.6 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ThiW PF09512.10 PVD19443.1 - 0.00089 19.4 2.1 0.003 17.7 2.1 1.8 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) UPF0182 PF03699.13 PVD19443.1 - 1.9 6.5 9.4 3.5 5.6 9.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) TMEM154 PF15102.6 PVD19443.1 - 8.1 6.3 9.3 0.5 10.3 0.1 3.0 3 0 0 3 3 3 0 TMEM154 protein family 7tm_1 PF00001.21 PVD19445.1 - 0.0018 17.7 7.5 0.2 10.9 0.8 2.3 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 PVD19445.1 - 0.048 13.6 0.7 0.048 13.6 0.7 2.8 2 1 0 2 2 2 0 TMEM154 protein family Gyro_capsid PF04162.12 PVD19445.1 - 0.051 12.0 0.1 0.071 11.6 0.1 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) UPF0697 PF15117.6 PVD19445.1 - 0.13 12.3 3.3 7.8 6.6 0.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0697 DUF4834 PF16118.5 PVD19445.1 - 1.4 10.0 0.0 1.4 10.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) LRRC37AB_C PF14914.6 PVD19445.1 - 8.5 6.3 10.9 0.2 11.6 1.6 2.3 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain HMG-CoA_red PF00368.18 PVD19446.1 - 1.3e-143 478.5 0.0 1.7e-143 478.1 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 PVD19446.1 - 7.5e-14 51.8 2.7 1.5e-13 50.9 2.7 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 PVD19446.1 - 2.6e-08 32.5 0.0 4.5e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Patched family DUF296 PF03479.15 PVD19446.1 - 0.13 12.7 0.4 1 9.8 0.0 2.5 2 1 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain DTW PF03942.15 PVD19448.1 - 1.2e-25 90.5 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 DTW domain ATPgrasp_N PF18130.1 PVD19449.1 - 2.7e-09 37.5 0.0 1.7e-08 34.9 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 PVD19449.1 - 2.7e-09 36.8 0.0 6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PVD19449.1 - 2.3e-06 27.4 0.0 7e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PVD19449.1 - 0.00087 19.4 0.7 0.0048 16.9 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PVD19449.1 - 0.0092 15.5 0.1 0.049 13.1 0.1 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 PVD19449.1 - 0.043 13.6 0.1 0.57 9.9 0.1 2.3 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MADF_DNA_bdg PF10545.9 PVD19449.1 - 0.17 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TLE_N PF03920.15 PVD19450.1 - 3.3e-51 172.8 11.2 4.8e-51 172.2 11.2 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 PVD19450.1 - 6.4e-18 64.8 15.7 0.0014 19.4 0.5 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD19450.1 - 1.7e-09 37.8 0.0 0.035 14.4 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD19450.1 - 0.015 14.6 0.0 1.8 7.8 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain Transketolase_N PF00456.21 PVD19450.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Cytochrom_D1 PF02239.16 PVD19450.1 - 0.098 11.2 0.0 0.93 8.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain SOG2 PF10428.9 PVD19450.1 - 6.4 5.9 7.0 8.1 5.5 7.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EST1_DNA_bind PF10373.9 PVD19451.1 - 4.9e-31 108.3 10.4 3.5e-30 105.4 0.2 3.1 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain EST1 PF10374.9 PVD19451.1 - 2.4e-22 80.1 1.5 2.4e-22 80.1 1.5 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_4 PF13638.6 PVD19451.1 - 0.0029 17.9 0.0 0.012 15.9 0.0 2.1 1 0 0 1 1 1 1 PIN domain Na_Ca_ex_C PF16494.5 PVD19451.1 - 3.7 8.0 6.3 12 6.3 0.0 3.3 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain Cadherin PF00028.17 PVD19452.1 - 5.2e-103 337.7 32.0 9.8e-19 67.6 0.0 13.2 12 2 2 14 14 14 11 Cadherin domain Cadherin_3 PF16184.5 PVD19452.1 - 1.8e-08 34.3 25.6 0.13 12.3 0.1 8.8 9 0 0 9 9 9 4 Cadherin-like Cadherin_2 PF08266.12 PVD19452.1 - 3.9e-05 23.4 0.0 1.1e+02 2.7 0.0 6.3 6 0 0 6 6 6 0 Cadherin-like Shisa PF13908.6 PVD19452.1 - 0.0024 18.2 0.1 0.0046 17.2 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Urm1 PF09138.11 PVD19452.1 - 0.12 12.7 0.2 0.65 10.4 0.1 2.2 2 0 0 2 2 2 0 Urm1 (Ubiquitin related modifier) Cadherin PF00028.17 PVD19453.1 - 3e-122 399.4 27.9 5.1e-19 68.5 0.1 14.6 14 0 0 14 14 14 13 Cadherin domain Cadherin_3 PF16184.5 PVD19453.1 - 2e-12 47.1 27.2 0.45 10.5 0.1 10.4 9 1 1 10 10 10 8 Cadherin-like Cadherin_2 PF08266.12 PVD19453.1 - 2.2e-09 37.0 0.0 9.7 6.1 0.0 8.7 10 0 0 10 10 10 2 Cadherin-like Invasin_D3 PF09134.10 PVD19453.1 - 1.9 8.8 20.5 5.2 7.5 0.1 7.2 7 0 0 7 7 7 0 Invasin, domain 3 Neur_chan_LBD PF02931.23 PVD19454.1 - 4.2e-57 193.1 0.2 5.5e-57 192.7 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19454.1 - 1.1e-22 81.3 0.5 1.6e-22 80.8 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SSF PF00474.17 PVD19455.1 - 4.4e-102 342.0 24.4 7.8e-59 199.6 5.1 2.2 1 1 1 2 2 2 2 Sodium:solute symporter family Ca_hom_mod PF14798.6 PVD19455.1 - 0.044 12.9 0.1 0.044 12.9 0.1 2.3 3 0 0 3 3 3 0 Calcium homeostasis modulator 7tm_2 PF00002.24 PVD19457.1 - 4.4e-05 22.9 6.8 5.6e-05 22.5 6.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Popeye PF04831.13 PVD19457.1 - 4.6 7.4 11.4 8.1 6.6 1.1 2.1 2 0 0 2 2 2 0 Popeye protein conserved region 7tm_2 PF00002.24 PVD19458.1 - 7.2e-15 54.9 22.2 1.6e-14 53.8 22.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 PVD19458.1 - 0.017 14.5 14.7 0.053 12.8 14.7 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2656 PF10847.8 PVD19458.1 - 0.049 13.7 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) SSF PF00474.17 PVD19459.1 - 1e-47 162.9 1.6 1.5e-47 162.4 1.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ca_hom_mod PF14798.6 PVD19459.1 - 0.032 13.4 0.1 0.032 13.4 0.1 2.3 3 0 0 3 3 3 0 Calcium homeostasis modulator Chromate_transp PF02417.15 PVD19459.1 - 0.14 12.3 10.1 1.6 8.8 10.1 2.1 1 1 0 1 1 1 0 Chromate transporter 7tm_2 PF00002.24 PVD19461.1 - 1e-14 54.4 21.7 2.3e-14 53.3 21.7 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF2656 PF10847.8 PVD19461.1 - 0.0053 16.9 0.1 0.0091 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2656) 7tm_2 PF00002.24 PVD19462.1 - 7.9e-09 35.2 4.4 1.1e-08 34.7 4.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Zip PF02535.22 PVD19464.1 - 6.1e-56 190.0 8.5 7.6e-56 189.7 8.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 PVD19464.1 - 0.0083 14.6 0.2 0.59 8.5 0.1 2.4 2 1 0 2 2 2 2 dsRNA-gated channel SID-1 RVT_1 PF00078.27 PVD19467.1 - 3.2e-26 92.2 0.0 4.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 PVD19469.1 - 5.4e-10 39.4 0.0 8.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD19469.1 - 1.6e-09 37.7 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19469.1 - 1.4e-08 35.2 0.0 2.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD19469.1 - 2.4e-07 30.8 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD19469.1 - 0.00017 21.8 0.0 0.00069 19.9 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19469.1 - 0.07 13.2 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD19470.1 - 3.3e-06 27.6 0.0 5.6e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD19470.1 - 0.0015 18.9 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD19470.1 - 0.005 16.9 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD19470.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain HPIP PF15226.6 PVD19471.1 - 0.064 13.7 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Ig_3 PF13927.6 PVD19472.1 - 6.9e-13 49.0 0.0 7.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19472.1 - 6.3e-12 45.4 0.0 1.4e-05 25.1 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD19472.1 - 8.7e-10 38.7 0.1 0.00044 20.4 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD19472.1 - 2.7e-09 37.1 0.0 0.00013 22.1 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19472.1 - 1.8e-08 34.6 0.0 0.0025 18.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD19472.1 - 1.6e-06 27.5 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 PVD19472.1 - 0.0006 19.8 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 2 CD47 immunoglobulin-like domain Ig_4 PF16680.5 PVD19472.1 - 0.0019 18.4 0.0 1.2 9.5 0.0 2.9 2 1 1 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 PVD19472.1 - 0.0088 16.2 0.1 4.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 PVD19472.1 - 0.013 15.5 0.0 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 PVD19472.1 - 0.045 12.5 0.0 0.74 8.5 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Forkhead PF00250.18 PVD19473.1 - 3.9e-17 62.3 0.1 6.5e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain Ig_3 PF13927.6 PVD19475.1 - 3.7e-18 65.9 0.2 1.1e-09 38.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19475.1 - 2.3e-17 62.9 0.1 2e-08 34.2 0.0 2.9 1 1 1 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD19475.1 - 3e-17 62.6 1.2 2.8e-09 37.0 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19475.1 - 3.7e-13 49.6 0.0 2.2e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19475.1 - 1.7e-12 47.5 0.6 7.1e-05 23.0 0.2 3.1 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD19475.1 - 0.0084 16.4 0.1 14 6.0 0.1 3.2 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD19475.1 - 0.094 12.3 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 PVD19476.1 - 2.9e-14 53.4 0.0 9.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19476.1 - 2.6e-11 43.4 0.0 2.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD19476.1 - 1.6e-10 41.2 0.1 0.00016 21.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD19476.1 - 4.2e-10 39.7 0.0 1e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19476.1 - 5.1e-10 39.5 0.0 6.4e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 PVD19476.1 - 0.00052 20.2 0.0 3.9 7.8 0.0 3.2 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD19476.1 - 0.0021 17.6 0.1 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19476.1 - 0.011 15.8 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 PVD19476.1 - 0.021 15.2 0.0 3.2 8.2 0.1 3.1 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CHZ PF09649.10 PVD19476.1 - 0.26 10.8 1.6 0.6 9.6 1.6 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ RsdA_SigD_bd PF16751.5 PVD19481.1 - 0.15 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Ank_2 PF12796.7 PVD19483.1 - 5.5e-33 113.4 2.3 1.7e-11 44.6 0.2 4.7 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD19483.1 - 5.7e-28 96.1 5.2 4.9e-05 23.6 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 PVD19483.1 - 3.7e-25 85.2 8.9 0.00024 21.3 0.0 8.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 PVD19483.1 - 1.6e-24 85.9 4.1 9.1e-05 22.9 0.0 7.5 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD19483.1 - 8.4e-19 67.4 5.4 0.007 16.7 0.0 7.1 4 1 3 7 7 7 5 Ankyrin repeats (many copies) BTB PF00651.31 PVD19484.1 - 3.6e-07 30.4 0.0 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sipho_tail PF05709.11 PVD19484.1 - 0.01 15.3 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Phage tail protein BACK PF07707.15 PVD19485.1 - 0.041 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 BTB And C-terminal Kelch wnt PF00110.19 PVD19491.1 - 8.1e-91 304.8 18.5 1.6e-51 175.7 0.1 2.0 2 0 0 2 2 2 2 wnt family Use1 PF09753.9 PVD19492.1 - 9e-17 61.6 0.6 3e-12 46.8 0.1 2.2 1 1 1 2 2 2 2 Membrane fusion protein Use1 DUF4601 PF15373.6 PVD19493.1 - 3.7e-05 22.9 12.2 0.0043 16.1 12.2 3.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4601) Ribosomal_L30 PF00327.20 PVD19493.1 - 0.088 12.7 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e GRIM-19 PF06212.12 PVD19494.1 - 3.8e-46 156.3 0.0 4.4e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Imm_superinfect PF14373.6 PVD19494.1 - 0.098 12.6 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Superinfection immunity protein NCU-G1 PF15065.6 PVD19495.1 - 5.1e-105 351.4 0.4 5.8e-105 351.2 0.4 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 CD34_antigen PF06365.12 PVD19495.1 - 0.00046 19.8 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family SKG6 PF08693.10 PVD19495.1 - 1.3 8.5 8.1 2.9 7.4 8.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_10 PF00331.20 PVD19496.1 - 1e-26 93.9 1.4 1.7e-26 93.2 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C1 PF18459.1 PVD19496.1 - 4e-13 49.3 13.3 4.1e-06 26.8 1.8 3.0 2 0 0 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain F-box-like PF12937.7 PVD19496.1 - 1.5e-05 24.8 2.5 4.9e-05 23.1 2.5 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 PVD19496.1 - 0.0018 19.1 1.8 0.0092 16.8 0.1 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat F-box PF00646.33 PVD19496.1 - 0.016 15.1 5.2 0.022 14.6 3.4 2.2 2 0 0 2 2 2 0 F-box domain Glyco_hydro_10 PF00331.20 PVD19497.1 - 1.9e-29 102.8 1.1 3.5e-29 102.0 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C1 PF18459.1 PVD19497.1 - 2.2e-17 63.0 24.0 3.6e-10 39.8 5.2 3.4 2 1 1 3 3 3 3 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain CBM_4_9 PF02018.17 PVD19497.1 - 4.4e-08 33.5 0.1 2.8e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain PCSK9_C3 PF18463.1 PVD19497.1 - 1.6 9.0 30.6 0.045 14.0 4.4 3.5 2 1 1 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C1 PF18459.1 PVD19498.1 - 9.1e-12 45.0 18.9 4.6e-08 33.1 3.7 3.4 2 2 1 3 3 3 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Glyco_hydro_10 PF00331.20 PVD19498.1 - 0.0023 17.1 0.1 0.0087 15.2 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.20 PVD19499.1 - 3.2e-50 171.1 6.5 4.2e-28 98.4 2.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 PCSK9_C1 PF18459.1 PVD19499.1 - 9.4e-28 96.2 44.2 2.5e-13 50.0 3.6 6.0 3 2 3 6 6 6 4 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain CBM_4_9 PF02018.17 PVD19499.1 - 4.4e-14 52.9 0.0 2.1e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 Carbohydrate binding domain PCSK9_C3 PF18463.1 PVD19499.1 - 0.002 18.3 56.5 0.021 15.0 4.7 6.5 3 2 3 6 6 6 3 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C2 PF18464.1 PVD19499.1 - 0.027 14.5 12.4 0.057 13.4 0.0 4.8 6 0 0 6 6 6 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain P_proprotein PF01483.20 PVD19499.1 - 0.076 13.1 0.1 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Proprotein convertase P-domain Tissue_fac PF01108.17 PVD19499.1 - 0.085 12.7 0.4 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Tissue factor DUF1786 PF08735.10 PVD19499.1 - 0.24 10.6 0.4 15 4.7 0.0 2.3 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Inhibitor_Mig-6 PF11555.8 PVD19499.1 - 0.29 11.3 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Glyco_hydro_10 PF00331.20 PVD19500.1 - 6.4e-32 111.0 0.9 9.8e-32 110.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C1 PF18459.1 PVD19500.1 - 5.2e-16 58.6 12.5 4.5e-11 42.7 3.4 2.6 2 0 0 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C2 PF18464.1 PVD19500.1 - 0.14 12.2 1.8 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Glyco_hydro_10 PF00331.20 PVD19501.1 - 1.8e-40 139.1 5.9 6.4e-22 78.1 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 PCSK9_C1 PF18459.1 PVD19501.1 - 1.8e-27 95.3 48.3 9.9e-10 38.4 4.1 6.6 2 2 4 6 6 6 6 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain CBM_4_9 PF02018.17 PVD19501.1 - 4.1e-09 36.8 0.2 4.3e-06 27.0 0.0 3.5 3 0 0 3 3 3 1 Carbohydrate binding domain PCSK9_C2 PF18464.1 PVD19501.1 - 0.0043 17.1 9.9 0.92 9.6 0.1 5.1 5 0 0 5 5 5 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain NnrU PF07298.11 PVD19501.1 - 0.055 13.0 0.2 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 NnrU protein PCSK9_C3 PF18463.1 PVD19501.1 - 0.17 12.1 67.9 0.088 13.1 3.2 6.7 2 2 4 6 6 6 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain HAUS6_N PF14661.6 PVD19502.1 - 2.9e-53 180.8 1.9 7e-53 179.6 1.9 1.7 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus EcoEI_R_C PF08463.10 PVD19502.1 - 0.023 14.8 0.6 0.056 13.6 0.6 1.6 1 0 0 1 1 1 0 EcoEI R protein C-terminal TPR_MLP1_2 PF07926.12 PVD19502.1 - 6.4 6.9 11.9 0.7 10.0 1.7 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein EcoEI_R_C PF08463.10 PVD19503.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal Mab-21 PF03281.14 PVD19504.1 - 0.00082 18.7 0.2 0.0016 17.8 0.2 1.4 1 0 0 1 1 1 1 Mab-21 protein SCIMP PF15050.6 PVD19504.1 - 0.018 15.5 0.1 0.039 14.4 0.1 1.7 1 0 0 1 1 1 0 SCIMP protein RRM_1 PF00076.22 PVD19505.1 - 8.5e-15 54.3 0.0 0.0009 19.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST-HTH PF12872.7 PVD19505.1 - 2e-11 43.5 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 OST-HTH/LOTUS domain TUDOR PF00567.24 PVD19505.1 - 0.0075 16.3 0.0 0.082 12.9 0.0 2.3 2 0 0 2 2 2 1 Tudor domain Raftlin PF15250.6 PVD19505.1 - 0.1 11.3 0.8 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 Raftlin Pkinase_Tyr PF07714.17 PVD19506.1 - 4.1e-96 321.2 0.0 6.3e-96 320.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 PVD19506.1 - 4e-50 168.6 3.9 8.1e-26 90.4 0.0 2.7 2 1 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 PVD19506.1 - 1.6e-42 145.8 0.0 2.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 PVD19506.1 - 8.1e-24 84.2 44.8 8.1e-24 84.2 44.8 3.1 3 0 0 3 3 3 1 Furin-like cysteine rich region fn3 PF00041.21 PVD19506.1 - 2.2e-17 63.2 8.2 1.7e-06 28.2 0.1 4.0 4 0 0 4 4 4 3 Fibronectin type III domain RP854 PF17460.2 PVD19506.1 - 0.14 11.9 1.5 0.25 11.1 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein RP854 Kinase-like PF14531.6 PVD19506.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Insulin_TMD PF17870.1 PVD19506.1 - 0.36 10.9 5.4 0.84 9.8 5.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mid2 PF04478.12 PVD19506.1 - 1.5 8.7 4.8 3.6 7.4 4.8 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4201 PF13870.6 PVD19507.1 - 0.02 14.6 27.8 0.078 12.7 23.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1192 PF06698.11 PVD19507.1 - 0.074 13.1 7.5 0.18 11.9 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Adenylsucc_synt PF00709.21 PVD19507.1 - 0.12 11.2 4.8 0.24 10.3 4.8 1.4 1 0 0 1 1 1 0 Adenylosuccinate synthetase GTP-bdg_M PF16360.5 PVD19507.1 - 0.19 12.4 0.4 0.19 12.4 0.4 3.0 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region DUF812 PF05667.11 PVD19507.1 - 0.46 9.3 21.5 0.75 8.6 21.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 PVD19507.1 - 0.66 10.0 28.4 7.3 6.7 5.7 3.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Adaptin_binding PF10199.9 PVD19507.1 - 1.6 9.4 10.6 1.1 9.8 8.3 2.1 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Fez1 PF06818.15 PVD19507.1 - 2.6 8.4 21.2 2.2 8.7 17.7 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 PVD19507.1 - 4.8 7.2 13.2 0.94 9.5 2.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 PVD19507.1 - 5.7 6.2 31.1 0.044 13.1 8.8 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 PVD19507.1 - 6.4 7.1 10.8 0.8 10.0 0.1 3.2 3 1 2 5 5 5 0 Haemolysin XhlA DUF4407 PF14362.6 PVD19507.1 - 7.3 5.8 15.2 0.79 9.0 10.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BTB_2 PF02214.22 PVD19508.1 - 1.5e-14 54.1 0.0 4.3e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 PVD19508.1 - 3.2e-05 24.0 0.0 0.00014 21.9 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain vWF_A PF12450.8 PVD19508.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor tRNA-synt_2b PF00587.25 PVD19509.1 - 9.1e-35 120.2 0.0 1.7e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PVD19509.1 - 1e-19 70.5 0.1 2.3e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 PVD19509.1 - 2.8e-16 59.3 0.0 7.8e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 PVD19509.1 - 6.6e-14 51.7 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GalKase_gal_bdg PF10509.9 PVD19510.1 - 1.2e-24 85.6 0.1 2e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 PVD19510.1 - 1.8e-12 47.3 1.5 3.3e-12 46.5 1.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PVD19510.1 - 1.7e-11 44.3 0.0 4.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Neur_chan_LBD PF02931.23 PVD19511.1 - 2.3e-65 220.1 4.0 3.4e-65 219.5 4.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19511.1 - 1.5e-47 162.7 0.8 2.4e-47 162.0 0.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Steroid_dh PF02544.16 PVD19512.1 - 1.7e-52 177.4 1.7 2.6e-52 176.8 1.7 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Mlf1IP PF10248.9 PVD19512.1 - 1e-08 35.3 6.0 1.4e-08 34.9 1.4 2.3 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF1295 PF06966.12 PVD19512.1 - 3.7e-05 23.4 0.2 5.5e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ig_3 PF13927.6 PVD19513.1 - 6.7e-30 103.5 1.7 3.1e-10 40.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD19513.1 - 6.7e-23 80.6 0.0 8.2e-08 32.2 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin I-set domain Peptidase_C14 PF00656.22 PVD19513.1 - 1.6e-22 80.7 0.0 2.4e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Ig_2 PF13895.6 PVD19513.1 - 7.2e-20 71.1 4.6 1.4e-06 28.6 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD19513.1 - 8e-12 45.2 2.2 0.00015 21.8 0.0 5.2 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD19513.1 - 1.9e-09 37.6 6.6 0.038 14.1 0.3 5.3 3 2 2 5 5 5 2 Immunoglobulin V-set domain MALT1_Ig PF18703.1 PVD19513.1 - 7e-07 29.3 0.0 4.6e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 MALT1 Ig-like domain Ig_4 PF16680.5 PVD19513.1 - 7.2e-05 23.0 0.3 1.7 9.0 0.0 3.5 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD19513.1 - 0.00014 22.2 3.0 0.44 11.0 0.0 3.9 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD19513.1 - 0.0059 16.1 0.1 2 8.1 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19513.1 - 0.071 13.2 0.2 0.8 9.8 0.0 2.8 2 1 1 3 3 3 0 Izumo-like Immunoglobulin domain CAF1A PF12253.8 PVD19514.1 - 3.6e-24 84.7 11.0 3.6e-24 84.7 11.0 6.3 5 1 0 5 5 5 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 PVD19514.1 - 1.3e-16 60.7 58.3 1.3e-16 60.7 58.3 3.6 3 1 1 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_C2 PF15539.6 PVD19514.1 - 6.3e-09 35.7 11.8 0.0017 17.9 0.0 4.3 5 0 0 5 5 5 3 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term BAR PF03114.18 PVD19515.1 - 7.2e-43 146.9 0.3 7.8e-43 146.8 0.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 PVD19515.1 - 0.0052 16.5 0.7 0.047 13.4 0.1 1.9 1 1 0 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 PVD19515.1 - 0.05 12.7 0.1 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_9 PF14604.6 PVD19516.1 - 2.5e-15 56.0 0.1 3.8e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD19516.1 - 4.1e-14 51.9 0.1 5.9e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD19516.1 - 5e-13 48.5 0.1 7.8e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 PVD19516.1 - 2.5e-05 24.0 0.2 3.1e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 PVD19516.1 - 0.014 14.6 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4953 PF16313.5 PVD19516.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Met-zincin KH_1 PF00013.29 PVD19517.1 - 3.8e-42 142.0 13.7 6.6e-19 67.5 1.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 PVD19517.1 - 8.7e-14 51.1 8.2 0.0004 20.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PVD19517.1 - 3.6e-06 26.8 3.1 0.051 13.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 PVD19517.1 - 0.0002 21.4 4.2 1.9 8.6 0.0 3.6 3 0 0 3 3 3 3 NusA-like KH domain Det1 PF09737.9 PVD19518.1 - 4.8e-166 552.9 4.6 6.3e-166 552.5 4.6 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Ras PF00071.22 PVD19519.1 - 5.8e-19 68.3 0.0 1.3e-18 67.1 0.0 1.6 1 1 1 2 2 2 1 Ras family Roc PF08477.13 PVD19519.1 - 1.8e-09 37.8 0.0 4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD19519.1 - 0.052 13.0 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD19519.1 - 0.079 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD19519.1 - 0.091 13.1 0.1 0.16 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 PVD19519.1 - 0.18 10.9 0.1 0.27 10.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 PVD19521.1 - 2.5e-18 66.2 0.0 3.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 PVD19521.1 - 0.16 11.4 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 PVD19522.1 - 1.4e-73 247.1 0.0 2e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 PVD19522.1 - 3.6e-47 159.8 3.2 6.7e-47 158.9 3.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 PVD19522.1 - 6.8e-19 68.2 0.9 1.6e-18 66.9 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 PVD19522.1 - 0.028 14.6 0.4 0.11 12.6 0.4 2.0 1 1 0 1 1 1 0 HAS barrel domain Anoctamin PF04547.12 PVD19523.1 - 1.2e-138 462.8 8.0 1.5e-138 462.5 8.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PVD19523.1 - 0.016 15.0 0.4 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Vfa1 PF08432.10 PVD19523.1 - 5.2 7.4 10.8 7.5 6.8 6.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Fibrinogen_C PF00147.18 PVD19524.1 - 4.5e-67 226.1 3.4 6.4e-67 225.6 3.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fez1 PF06818.15 PVD19524.1 - 0.0016 18.9 8.0 0.0016 18.9 8.0 2.2 1 1 0 2 2 2 1 Fez1 Spc7 PF08317.11 PVD19524.1 - 0.036 13.0 11.2 0.72 8.7 4.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein AF0941-like PF14591.6 PVD19524.1 - 0.1 13.1 0.8 0.24 12.0 0.8 1.5 1 0 0 1 1 1 0 AF0941-like V_ATPase_I PF01496.19 PVD19524.1 - 0.14 10.1 3.9 0.4 8.5 3.9 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 PVD19524.1 - 0.84 9.8 19.3 0.26 11.5 3.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 PVD19524.1 - 1.1 8.4 3.8 0.44 9.7 1.0 1.7 2 0 0 2 2 2 0 TMPIT-like protein Cnn_1N PF07989.11 PVD19524.1 - 1.6 9.0 10.0 14 5.9 0.0 3.8 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 PVD19524.1 - 1.8 8.6 6.4 6.5 6.8 0.6 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) YabA PF06156.13 PVD19524.1 - 3.8 8.2 12.0 35 5.1 0.6 4.2 2 2 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 PVD19524.1 - 4.1 7.4 23.1 0.65 10.0 3.0 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ski_Sno PF02437.17 PVD19526.1 - 7.6e-37 125.4 0.0 2e-36 124.0 0.1 1.6 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 PVD19526.1 - 1.5e-30 105.2 4.5 1.5e-30 105.2 4.5 2.0 3 0 0 3 3 3 1 c-SKI Smad4 binding domain Pkinase PF00069.25 PVD19527.1 - 1.3e-63 214.8 0.0 2.8e-63 213.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RCC1 PF00415.18 PVD19527.1 - 1.2e-52 176.3 19.9 2.1e-09 37.9 0.2 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 PVD19527.1 - 3e-38 131.6 0.0 4.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 PVD19527.1 - 9e-31 105.0 13.3 2.8e-06 27.0 1.2 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 PVD19527.1 - 3.4e-05 23.3 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD19527.1 - 0.0013 17.6 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SH3_19 PF18597.1 PVD19527.1 - 0.098 12.5 0.1 0.38 10.6 0.1 2.0 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain LSDAT_euk PF18139.1 PVD19530.1 - 1.4e-94 316.4 2.1 6.4e-91 304.4 2.1 2.3 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 PVD19530.1 - 1.4e-16 60.3 0.1 2.5e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote TRPM_tetra PF16519.5 PVD19530.1 - 3.6e-16 59.0 3.9 1.1e-15 57.4 3.9 1.9 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 PVD19530.1 - 6.9e-13 48.4 16.8 1e-12 47.8 16.8 1.2 1 0 0 1 1 1 1 Ion transport protein Apo-VLDL-II PF05418.11 PVD19530.1 - 0.054 14.1 0.3 0.13 12.8 0.3 1.7 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) YqaJ PF09588.10 PVD19531.1 - 1.8e-24 86.6 0.0 3.3e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain MRG PF05712.13 PVD19532.1 - 3.4e-51 173.4 1.1 3.4e-51 173.4 1.1 2.2 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 PVD19532.1 - 2e-15 56.4 1.3 5.2e-15 55.1 1.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain YL1 PF05764.13 PVD19532.1 - 0.0094 16.1 24.5 0.0094 16.1 24.5 1.5 2 0 0 2 2 2 1 YL1 nuclear protein zf-C2H2_6 PF13912.6 PVD19532.1 - 0.094 12.7 11.1 0.24 11.4 2.5 2.7 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 PVD19532.1 - 0.14 13.1 11.8 1.3 10.0 1.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger MRP-S26 PF14943.6 PVD19532.1 - 0.44 10.4 24.0 2.2 8.1 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Ndc1_Nup PF09531.10 PVD19532.1 - 0.53 8.9 5.1 0.7 8.5 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAGA-Tad1 PF12767.7 PVD19532.1 - 0.65 9.7 17.1 0.095 12.4 11.5 2.5 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CDC45 PF02724.14 PVD19532.1 - 4.2 5.5 17.1 6.4 4.9 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BORCS8 PF10167.9 PVD19533.1 - 1.4e-14 54.0 1.9 1.4e-14 54.0 1.9 2.5 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 CBM_14 PF01607.24 PVD19534.1 - 3.9e-36 123.0 64.6 9.5e-08 32.1 2.6 7.3 7 0 0 7 7 7 7 Chitin binding Peritrophin-A domain Cohesin_load PF10345.9 PVD19535.1 - 1.5e-83 281.3 13.1 1.7e-83 281.1 13.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 PVD19535.1 - 3.6e-08 33.6 4.3 0.058 13.7 0.0 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD19535.1 - 0.00016 21.2 0.1 0.00016 21.2 0.1 3.4 2 1 1 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 PVD19535.1 - 0.0024 17.9 3.7 21 5.6 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19535.1 - 0.0027 17.8 5.7 4.1 7.9 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19535.1 - 0.0032 17.2 2.3 2.6 8.0 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat HemY_N PF07219.13 PVD19535.1 - 0.24 11.6 3.1 16 5.7 0.0 4.1 3 2 1 5 5 5 0 HemY protein N-terminus TPR_7 PF13176.6 PVD19535.1 - 1.4 9.1 4.4 5.6 7.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD19535.1 - 1.8 9.2 7.3 31 5.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S11 PF00411.19 PVD19536.1 - 5e-34 117.0 1.0 6.4e-34 116.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 P66_CC PF16563.5 PVD19537.1 - 1.9e-14 53.0 3.0 1.9e-14 53.0 3.0 3.0 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 PVD19537.1 - 0.00022 20.8 2.9 0.00044 19.8 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger HECT PF00632.25 PVD19538.1 - 4.7e-98 328.5 0.1 6.4e-98 328.0 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 PVD19538.1 - 2.4e-52 174.7 21.3 6.7e-14 51.7 1.2 5.0 4 0 0 4 4 4 4 WW domain C2 PF00168.30 PVD19538.1 - 2e-22 79.4 0.0 5.8e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain PI3K_C2 PF00792.24 PVD19538.1 - 0.089 12.7 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 YjeF_N PF03853.15 PVD19539.1 - 6.4e-16 58.7 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus LSM14 PF12701.7 PVD19539.1 - 6.2e-10 39.0 0.4 1.4e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 PVD19539.1 - 9.2e-06 26.5 0.2 9.2e-06 26.5 0.2 2.3 2 0 0 2 2 2 1 FDF domain DUF3552 PF12072.8 PVD19539.1 - 0.019 14.4 0.0 0.24 10.8 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Methyltransf_31 PF13847.6 PVD19539.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zinc-ribbons_6 PF07191.12 PVD19539.1 - 0.11 12.4 0.2 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons NAD_binding_2 PF03446.15 PVD19539.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1647 PF07801.11 PVD19540.1 - 3.2e-11 43.2 0.1 6.3e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Glycos_transf_2 PF00535.26 PVD19541.1 - 1.7e-28 99.5 0.0 3.1e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD19541.1 - 1.4e-15 57.6 0.8 2.3e-15 57.0 0.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PVD19541.1 - 1.2e-09 38.4 0.1 2.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD19541.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD19541.1 - 2.3e-05 23.9 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 PVD19541.1 - 0.021 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 DinI PF06183.13 PVD19541.1 - 0.18 12.2 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 DinI-like family Glycos_transf_2 PF00535.26 PVD19542.1 - 9.3e-28 97.2 0.0 1.5e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD19542.1 - 1.7e-17 63.8 0.4 2.9e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PVD19542.1 - 4.6e-06 26.2 0.1 9.5e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PVD19542.1 - 5e-06 26.2 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF885 PF05960.11 PVD19543.1 - 6e-38 131.8 0.0 9.8e-37 127.8 0.0 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) RRM_1 PF00076.22 PVD19544.1 - 3.6e-19 68.3 0.1 6.6e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD19544.1 - 1.7e-05 24.8 0.4 5.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 PVD19544.1 - 0.00037 20.1 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD19544.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif FAM184 PF15665.5 PVD19546.1 - 2.6e-07 30.6 38.3 8.2e-05 22.5 28.5 2.3 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B DUF4618 PF15397.6 PVD19546.1 - 0.073 12.5 27.2 0.019 14.4 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) OmpH PF03938.14 PVD19546.1 - 0.12 12.7 40.5 0.17 12.2 7.6 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF5517 PF17639.2 PVD19546.1 - 0.61 10.4 6.7 1.8 8.9 0.5 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5517) Mt_ATP-synt_D PF05873.12 PVD19546.1 - 0.94 9.3 13.8 2.8 7.8 0.7 3.3 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Fez1 PF06818.15 PVD19546.1 - 1 9.7 40.7 0.24 11.8 16.1 3.0 1 1 2 3 3 3 0 Fez1 UPF0242 PF06785.11 PVD19546.1 - 1.2 9.2 40.3 0.083 13.0 15.5 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 PVD19546.1 - 1.7 7.9 33.2 4 6.7 26.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 PVD19546.1 - 2 8.7 5.3 57 4.1 0.4 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PVD19546.1 - 2.1 7.2 37.5 0.99 8.2 6.6 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 PVD19546.1 - 2.8 7.5 37.9 24 4.4 30.2 3.1 1 1 1 2 2 2 0 Intermediate filament protein YabA PF06156.13 PVD19546.1 - 3.9 8.2 23.7 4.3 8.0 6.2 3.8 1 1 2 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 PVD19546.1 - 4.4 7.5 22.1 2.8 8.1 3.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 PVD19546.1 - 5.2 7.2 13.3 8.3 6.5 1.2 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 PVD19546.1 - 5.5 7.0 11.7 30 4.6 1.5 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PVD19546.1 - 7.2 6.7 16.6 1.8 8.6 2.5 3.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) ADIP PF11559.8 PVD19546.1 - 7.7 6.6 42.6 0.63 10.1 9.2 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 PVD19546.1 - 7.9 7.2 44.5 1.3 9.7 7.6 4.8 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C2H2 PF00096.26 PVD19548.1 - 1.7e-15 56.5 21.6 2.1e-05 24.7 3.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD19548.1 - 2.7e-13 49.7 22.9 2.1e-07 31.1 0.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD19548.1 - 3.2e-08 33.7 18.2 0.00021 21.9 1.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-WRNIP1_ubi PF18279.1 PVD19548.1 - 0.01 16.4 0.2 0.027 15.1 0.2 1.8 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-met PF12874.7 PVD19548.1 - 0.017 15.5 8.4 0.05 14.0 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD19548.1 - 0.025 14.9 0.9 0.072 13.4 0.9 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 PVD19548.1 - 0.044 14.1 4.7 0.12 12.7 4.3 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PVD19548.1 - 0.08 13.0 14.6 0.49 10.5 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 PVD19548.1 - 0.11 13.1 12.0 0.7 10.6 0.2 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 PVD19548.1 - 0.12 12.0 0.5 0.12 12.0 0.5 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 PVD19548.1 - 0.3 11.4 11.3 3.4 8.1 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 PVD19548.1 - 0.8 9.7 5.7 1.1 9.2 1.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PVD19549.1 - 1.5e-22 78.7 99.0 0.00084 19.7 1.5 12.4 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD19549.1 - 6.2e-15 54.6 91.6 0.013 16.2 1.1 12.9 12 0 0 12 12 12 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD19549.1 - 4.7e-12 45.7 72.5 3e-05 24.2 0.1 11.1 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD19549.1 - 1.2e-05 25.5 43.5 0.21 11.9 0.5 9.6 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD19549.1 - 0.0055 17.1 61.6 0.42 11.1 0.5 11.5 11 0 0 11 11 11 4 Zinc-finger of C2H2 type DUF1677 PF07911.13 PVD19549.1 - 0.012 15.9 4.3 0.012 15.9 4.3 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) TF_Zn_Ribbon PF08271.12 PVD19549.1 - 1.8 8.1 23.2 1.3 8.6 2.0 6.7 5 1 1 6 6 6 0 TFIIB zinc-binding zf-C2H2_6 PF13912.6 PVD19549.1 - 7.2 6.7 64.1 0.15 12.1 0.6 9.0 9 0 0 9 9 9 0 C2H2-type zinc finger zf_C2H2_6 PF18450.1 PVD19549.1 - 9.7 6.0 10.2 42 4.0 0.1 4.1 3 0 0 3 3 3 0 Zinc Finger domain LRR_8 PF13855.6 PVD19550.1 - 7.9e-60 198.5 54.6 4.5e-14 51.9 2.9 8.4 2 2 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 PVD19550.1 - 3.5e-39 132.1 35.6 9.1e-06 25.9 0.0 10.0 8 2 0 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD19550.1 - 1e-21 74.1 23.4 4.3 8.3 0.1 14.8 15 1 0 15 15 15 6 Leucine Rich Repeat LRR_5 PF13306.6 PVD19550.1 - 2.3e-20 72.8 4.8 1e-06 28.8 0.1 4.2 2 2 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD19550.1 - 3.9e-08 33.0 10.1 0.22 11.0 0.3 4.3 2 1 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 PVD19550.1 - 1e-07 31.4 35.1 0.87 9.8 0.0 12.4 14 0 0 14 14 14 4 Leucine Rich repeat LRRNT PF01462.18 PVD19550.1 - 0.027 14.1 5.7 0.048 13.3 3.6 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Ank_2 PF12796.7 PVD19551.1 - 3.4e-42 142.9 3.5 2.8e-14 53.5 0.3 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD19551.1 - 1.1e-37 127.9 4.2 2.1e-11 44.1 0.2 6.6 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD19551.1 - 2.5e-37 126.4 5.9 1.2e-08 35.1 0.0 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD19551.1 - 1.7e-35 119.9 9.1 4e-07 30.2 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 PVD19551.1 - 1.7e-31 104.7 6.7 8.7e-06 25.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Death PF00531.22 PVD19551.1 - 3.2e-11 43.2 0.4 1.1e-10 41.6 0.1 2.2 2 0 0 2 2 2 1 Death domain Roc PF08477.13 PVD19551.1 - 4.8e-06 26.8 0.4 0.0004 20.6 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 PVD19551.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 PVD19551.1 - 0.034 13.8 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras family PKS_DE PF18369.1 PVD19551.1 - 0.28 11.8 2.4 0.52 10.9 0.5 2.4 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Herpes_UL1 PF05259.11 PVD19554.1 - 0.17 11.9 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein L SSP160 PF06933.11 PVD19554.1 - 0.19 9.9 2.5 0.22 9.7 2.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 PVD19555.1 - 1.2e-73 247.7 0.0 1.6e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD19555.1 - 8.1e-38 130.2 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD19555.1 - 2.3e-07 29.9 0.1 2.3e-07 29.9 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PVD19555.1 - 2.9e-05 23.5 0.2 5.4e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PVD19555.1 - 3.1e-05 23.7 0.2 5.3e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PVD19555.1 - 0.00091 18.6 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD19555.1 - 0.009 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 PVD19555.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HU-CCDC81_bac_2 PF18175.1 PVD19555.1 - 0.097 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Choline_kinase PF01633.20 PVD19555.1 - 0.097 12.2 0.6 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase PTPLA PF04387.14 PVD19556.1 - 1.1e-36 126.1 6.4 1.1e-36 126.1 6.4 1.4 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 PVD19556.1 - 5.8e-06 27.2 0.0 9.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CS domain Death PF00531.22 PVD19557.1 - 7.9e-13 48.4 0.3 1.7e-12 47.3 0.3 1.5 1 0 0 1 1 1 1 Death domain Roc PF08477.13 PVD19557.1 - 6e-10 39.4 0.0 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 PVD19557.1 - 4.5e-08 33.1 0.0 1.3e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 PVD19557.1 - 0.00096 18.8 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Phage_Coat_Gp8 PF05371.12 PVD19557.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Phage major coat protein, Gp8 FERM_M PF00373.18 PVD19558.1 - 2.9e-21 76.1 0.0 6.7e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PVD19558.1 - 6.7e-13 48.4 0.2 1.8e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 PVD19558.1 - 2e-08 34.5 0.1 3.7e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Orf78 PF06024.12 PVD19559.1 - 0.0032 17.7 2.8 0.45 10.8 0.0 2.4 2 0 0 2 2 2 2 Orf78 (ac78) SseC PF04888.12 PVD19559.1 - 0.0069 16.0 2.8 0.011 15.4 2.8 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family RPM2 PF08579.11 PVD19559.1 - 0.0081 16.6 0.1 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Spt20 PF12090.8 PVD19559.1 - 0.014 15.0 16.8 0.023 14.3 16.8 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PVD19559.1 - 0.02 14.9 15.1 0.027 14.5 15.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF702 PF05142.12 PVD19559.1 - 0.034 14.6 1.9 0.056 13.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Na_trans_assoc PF06512.13 PVD19559.1 - 0.12 12.6 4.5 0.19 12.0 4.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Androgen_recep PF02166.16 PVD19559.1 - 0.66 8.7 14.8 0.85 8.4 14.8 1.3 1 0 0 1 1 1 0 Androgen receptor Suf PF05843.14 PVD19559.1 - 2.5 8.0 9.2 4.3 7.2 9.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 4F5 PF04419.14 PVD19560.1 - 0.00011 23.0 18.2 0.00011 23.0 18.2 2.6 1 1 1 2 2 2 1 4F5 protein family Presenilin PF01080.17 PVD19560.1 - 5.2 5.7 6.2 5.4 5.7 6.2 1.0 1 0 0 1 1 1 0 Presenilin PC4 PF02229.16 PVD19561.1 - 3e-23 81.2 0.0 4.6e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ketoacyl-synt PF00109.26 PVD19562.1 - 9.5e-27 94.2 0.0 3e-26 92.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF2615 PF11027.8 PVD19563.1 - 0.0024 18.0 0.4 0.0024 18.0 0.4 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2615) DUF981 PF06168.11 PVD19563.1 - 3.6 7.5 16.4 0.046 13.6 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF981) ubiquitin PF00240.23 PVD19564.1 - 1.1e-09 37.8 0.2 1.1e-09 37.8 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PVD19564.1 - 0.0011 18.7 0.7 0.0035 17.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PVD19564.1 - 0.023 15.3 0.3 2.9 8.5 0.0 3.5 3 1 1 4 4 4 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PVD19564.1 - 0.03 14.7 2.0 0.062 13.7 0.6 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain XPA_C PF05181.12 PVD19565.1 - 2.1e-25 88.4 0.5 3.6e-25 87.7 0.5 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 PVD19565.1 - 2.9e-10 40.0 5.7 2.9e-10 40.0 5.7 1.9 2 0 0 2 2 2 1 XPA protein N-terminal DpnI PF06044.12 PVD19565.1 - 0.018 14.7 0.3 0.036 13.7 0.3 1.4 1 0 0 1 1 1 0 Dam-replacing family YhfH PF14149.6 PVD19565.1 - 0.038 14.0 2.2 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 YhfH-like protein Nudix_N_2 PF14803.6 PVD19565.1 - 0.89 9.5 4.1 15 5.6 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal zf_UBZ PF18439.1 PVD19565.1 - 2.1 8.0 8.0 0.67 9.6 0.3 3.1 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger TipAS PF07739.13 PVD19565.1 - 2.6 8.6 8.5 0.22 12.1 2.9 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Gelsolin PF00626.22 PVD19567.1 - 1.7e-13 50.3 0.2 0.00058 19.7 0.0 5.6 5 0 0 5 5 5 4 Gelsolin repeat Glyco_tranf_2_4 PF13704.6 PVD19567.1 - 0.012 16.1 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Dimerisation2 PF16864.5 PVD19569.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 PVD19569.1 - 0.0092 16.0 0.0 0.072 13.1 0.0 2.5 3 0 0 3 3 3 1 Dimerisation domain DUF3915 PF13054.6 PVD19569.1 - 0.17 11.9 1.0 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF2951 PF11166.8 PVD19569.1 - 0.33 11.2 3.4 0.53 10.5 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) NOA36 PF06524.12 PVD19569.1 - 2.9 7.1 5.2 4.8 6.4 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 PVD19569.1 - 4.3 7.8 9.7 0.28 11.6 4.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_2 PF00891.18 PVD19570.1 - 2.9e-42 144.3 0.0 3.7e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 PVD19570.1 - 8.5e-07 29.7 0.0 1.2e-05 26.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD19570.1 - 7.5e-06 26.6 0.0 2.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PVD19570.1 - 8.7e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PVD19570.1 - 4.5e-05 23.3 0.0 8.4e-05 22.4 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD19570.1 - 6.1e-05 23.6 0.0 0.00016 22.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD19570.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD19570.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 PVD19570.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 PVD19570.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) adh_short PF00106.25 PVD19571.1 - 1.6e-41 141.9 0.3 6e-41 140.0 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19571.1 - 9.9e-30 103.8 0.2 2.1e-29 102.7 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19571.1 - 1.4e-07 31.6 0.2 2.5e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 PVD19571.1 - 9.4e-05 23.1 0.1 0.00044 20.9 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 PVD19571.1 - 0.00013 21.6 0.1 0.00029 20.4 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD19571.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 PVD19571.1 - 0.02 15.5 0.1 0.13 13.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SLC12 PF03522.15 PVD19572.1 - 2e-135 452.1 0.0 2.5e-135 451.9 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 PVD19572.1 - 7.5e-103 344.7 29.2 8.9e-103 344.4 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease PKD_channel PF08016.12 PVD19573.1 - 0.061 12.0 0.1 0.081 11.6 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel SLC12 PF03522.15 PVD19574.1 - 2.4e-13 49.9 0.1 2.4e-13 49.9 0.1 1.5 2 0 0 2 2 2 1 Solute carrier family 12 SLC12 PF03522.15 PVD19575.1 - 1.5e-135 452.6 0.0 1.9e-135 452.2 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 PVD19575.1 - 5.5e-112 374.8 23.5 6.7e-112 374.5 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 PVD19576.1 - 6e-138 460.5 0.1 7.3e-138 460.2 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 PVD19576.1 - 2.1e-100 336.6 25.9 2.8e-100 336.2 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease RINGv PF12906.7 PVD19578.1 - 7e-15 54.9 10.1 1.6e-14 53.7 10.1 1.7 1 0 0 1 1 1 1 RING-variant domain NUDIX PF00293.28 PVD19578.1 - 0.00049 20.2 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-RING_2 PF13639.6 PVD19578.1 - 0.019 15.3 8.7 0.019 15.3 8.7 2.0 2 0 0 2 2 2 0 Ring finger domain PTPLA PF04387.14 PVD19578.1 - 0.12 12.1 1.3 0.19 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA DZF PF07528.14 PVD19579.1 - 2.2e-76 256.8 0.0 4.2e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 PVD19579.1 - 5.3e-22 77.5 12.6 1.8e-06 28.1 0.1 3.8 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD19579.1 - 1.6e-16 60.1 11.1 2.3e-05 24.6 1.9 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PVD19579.1 - 0.0031 17.8 19.5 1.1 9.6 0.5 4.4 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 PVD19579.1 - 0.62 9.9 17.4 2.2 8.1 1.6 3.7 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.6 PVD19579.1 - 0.71 10.9 9.0 22 6.2 0.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DBF PF07535.12 PVD19579.1 - 4.8 7.4 15.8 6 7.1 1.2 3.6 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.26 PVD19579.1 - 6.6 7.4 14.0 8.4 7.1 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type PH PF00169.29 PVD19580.1 - 3e-07 30.9 0.4 7.7e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 PVD19580.1 - 6.8e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.6 PVD19580.1 - 0.015 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 PVD19580.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain F-box_5 PF18511.1 PVD19580.1 - 2.5 7.8 4.1 22 4.7 0.3 2.5 2 0 0 2 2 2 0 F-box N6-adenineMlase PF10237.9 PVD19581.1 - 2.2e-05 24.3 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase FapA PF03961.13 PVD19582.1 - 1.4 7.4 4.9 3.2 6.2 4.9 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 PVD19582.1 - 6.3 7.0 10.9 1.4 9.1 4.2 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ProQ_C PF17516.2 PVD19584.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Tetraspanin PF00335.20 PVD19586.1 - 3.8e-43 147.8 17.3 4.4e-43 147.6 17.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2371 PF10177.9 PVD19586.1 - 2.8 8.1 5.3 42 4.3 2.8 2.5 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) CD20 PF04103.15 PVD19586.1 - 3.6 7.6 17.3 3.3 7.8 12.2 2.7 1 1 1 2 2 2 0 CD20-like family GRAM PF02893.20 PVD19587.1 - 2e-17 63.1 0.0 3.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain IBN_N PF03810.19 PVD19589.1 - 1.2e-15 57.2 0.1 2.5e-14 52.9 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 PVD19589.1 - 0.0013 19.1 0.7 0.086 13.2 0.1 3.0 2 1 0 2 2 2 1 HEAT repeats FANCI_S3 PF14677.6 PVD19589.1 - 0.0067 16.2 0.1 0.0067 16.2 0.1 3.0 3 1 0 3 3 3 1 FANCI solenoid 3 DUF1539 PF07560.11 PVD19589.1 - 0.022 14.8 0.1 0.081 13.0 0.1 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) HEAT PF02985.22 PVD19589.1 - 0.065 13.5 0.1 9.6 6.8 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Casc1_N PF15927.5 PVD19589.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Xpo1 PF08389.12 PVD19589.1 - 0.13 12.3 9.8 0.26 11.3 1.3 4.6 3 2 2 5 5 5 0 Exportin 1-like protein Sema PF01403.19 PVD19590.1 - 6.1e-72 242.8 0.0 8.4e-45 153.3 0.0 2.1 1 1 1 2 2 2 2 Sema domain PSI PF01437.25 PVD19590.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.2 2 0 0 2 2 2 0 Plexin repeat Glyco_transf_10 PF00852.19 PVD19592.1 - 2e-42 144.9 2.5 3.8e-42 144.0 2.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD19592.1 - 1.4e-12 48.0 0.4 3.3e-12 46.8 0.1 1.8 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 PVD19592.1 - 0.032 14.6 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-C2H2 PF00096.26 PVD19593.1 - 1.9e-37 125.7 90.6 2.7e-05 24.4 0.2 11.6 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD19593.1 - 2.4e-30 103.6 74.7 0.00023 21.4 0.5 12.4 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD19593.1 - 4e-28 95.7 84.0 0.0013 19.4 0.2 11.5 11 0 0 11 11 11 11 C2H2-type zinc finger zf-met PF12874.7 PVD19593.1 - 4.8e-10 39.5 50.7 0.0051 17.2 0.7 10.1 10 0 0 10 10 10 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD19593.1 - 2.9e-08 33.8 45.9 1.4 9.3 1.1 10.5 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding DUF1390 PF07150.11 PVD19593.1 - 0.035 13.8 0.1 0.13 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) ADK_lid PF05191.14 PVD19593.1 - 0.15 12.0 25.4 0.29 11.2 1.0 5.5 3 1 0 4 4 4 0 Adenylate kinase, active site lid zf_ZIC PF18366.1 PVD19593.1 - 0.51 10.5 22.1 0.24 11.6 0.4 5.2 3 2 2 5 5 5 0 Zic proteins zinc finger domain Bac_small_YrzI PF09501.10 PVD19593.1 - 0.58 10.3 2.6 2.2 8.5 2.6 2.0 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) zf-C2H2_2 PF12756.7 PVD19593.1 - 3 8.2 55.9 1.5 9.2 6.4 8.5 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf_PR_Knuckle PF18445.1 PVD19593.1 - 3.5 7.5 8.8 8.2 6.3 0.2 4.5 4 0 0 4 4 4 0 PR zinc knuckle motif Zn-ribbon_8 PF09723.10 PVD19593.1 - 5.8 7.1 36.5 4.6 7.4 0.2 7.5 3 2 6 9 9 9 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 PVD19593.1 - 8.7 6.5 80.0 0.039 14.0 5.8 10.6 11 1 0 11 11 11 0 C2H2-type zinc finger Peptidase_M28 PF04389.17 PVD19594.1 - 2.6e-08 33.8 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 PVD19594.1 - 0.0004 19.9 0.5 0.0026 17.3 0.5 2.4 1 1 0 1 1 1 1 Nicastrin AMP-binding PF00501.28 PVD19595.1 - 6.6e-43 146.9 0.0 2.7e-31 108.6 0.0 2.2 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD19595.1 - 2.6e-06 28.3 0.0 4.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD19596.1 - 2.2e-104 349.4 0.0 3.6e-51 174.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD19596.1 - 5.1e-13 49.8 0.0 1.8e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Cas_Csy1 PF09611.10 PVD19596.1 - 0.022 13.8 0.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy1) AMP-binding PF00501.28 PVD19597.1 - 1.4e-50 172.2 0.0 1.7e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD19597.1 - 3.6e-06 27.8 0.0 6.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3574 PF12098.8 PVD19598.1 - 0.043 13.6 0.2 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) DUF1835 PF08874.10 PVD19598.1 - 0.053 13.7 0.3 0.066 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Trypsin PF00089.26 PVD19599.1 - 3.8e-39 134.8 0.9 4.4e-39 134.6 0.9 1.0 1 0 0 1 1 1 1 Trypsin RVT_1 PF00078.27 PVD19602.1 - 8.9e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KH_1 PF00013.29 PVD19604.1 - 3.6e-27 94.0 2.8 1.3e-15 56.9 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 PVD19604.1 - 0.0014 18.5 0.3 0.38 10.6 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 PVD19604.1 - 0.0024 17.7 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 PVD19605.1 - 3.8e-12 45.9 6.2 3.8e-12 45.9 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD19605.1 - 1e-05 25.3 6.7 1e-05 25.3 6.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD19605.1 - 3.3e-05 23.7 5.5 3.3e-05 23.7 5.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 PVD19605.1 - 0.017 14.9 1.3 0.017 14.9 1.3 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PVD19605.1 - 0.05 13.6 6.7 0.047 13.7 1.9 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD19605.1 - 0.086 13.0 9.1 0.17 12.0 7.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD19605.1 - 0.27 11.1 12.0 0.055 13.3 8.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.9 PVD19605.1 - 1.8 8.1 12.0 3 7.4 12.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_2 PF00152.20 PVD19608.1 - 2.7e-90 302.7 0.4 7.7e-81 271.6 0.0 3.0 2 1 1 3 3 3 2 tRNA synthetases class II (D, K and N) Vps51 PF08700.11 PVD19608.1 - 2e-16 59.9 3.4 8.6e-16 57.8 3.4 2.2 1 0 0 1 1 1 1 Vps51/Vps67 tRNA_anti-codon PF01336.25 PVD19608.1 - 8.5e-12 44.9 0.1 4.9e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Sec5 PF15469.6 PVD19608.1 - 0.00015 21.6 0.1 0.00064 19.6 0.1 2.1 1 0 0 1 1 1 1 Exocyst complex component Sec5 rhaM PF05336.13 PVD19608.1 - 0.079 13.0 1.6 0.26 11.4 1.6 1.9 1 0 0 1 1 1 0 L-rhamnose mutarotase Dor1 PF04124.12 PVD19608.1 - 0.11 11.2 7.0 0.21 10.2 2.3 3.0 3 0 0 3 3 3 0 Dor1-like family DUF4539 PF15072.6 PVD19608.1 - 0.17 12.0 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DRY_EERY PF09750.9 PVD19608.1 - 3.6 7.8 7.6 0.29 11.4 1.0 2.4 2 0 0 2 2 2 0 Alternative splicing regulator Thymidylate_kin PF02223.17 PVD19609.1 - 1.8e-11 44.0 0.3 2e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 PVD19609.1 - 6.4e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD19609.1 - 1.1e-05 26.0 0.9 0.00071 20.1 0.7 2.9 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 PVD19609.1 - 1.4e-05 25.1 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 Deoxynucleoside kinase NACHT PF05729.12 PVD19609.1 - 2.8e-05 24.1 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 PVD19609.1 - 0.0021 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PVD19609.1 - 0.0035 17.8 0.0 0.008 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 PVD19609.1 - 0.0061 16.3 1.2 0.42 10.3 0.3 2.3 2 0 0 2 2 2 1 Cytidylate kinase NB-ARC PF00931.22 PVD19609.1 - 0.0064 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 PVD19609.1 - 0.0065 16.9 0.7 0.15 12.5 0.7 2.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PVD19609.1 - 0.0096 15.8 2.4 0.083 12.8 0.2 2.2 2 0 0 2 2 2 1 NTPase AAA_23 PF13476.6 PVD19609.1 - 0.055 14.0 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF884 PF05959.11 PVD19609.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) AAA_22 PF13401.6 PVD19609.1 - 0.062 13.6 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PVD19609.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SKI PF01202.22 PVD19609.1 - 0.095 12.8 1.9 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.6 PVD19609.1 - 0.12 12.6 0.1 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PVD19609.1 - 0.13 11.9 0.2 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 PVD19609.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 PVD19609.1 - 0.17 12.0 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Lectin_C PF00059.21 PVD19610.1 - 3.5e-12 47.0 0.1 7.3e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Lectin C-type domain VWA PF00092.28 PVD19611.1 - 1.4e-34 119.9 6.3 1.5e-17 64.4 0.1 3.2 2 1 1 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19611.1 - 2.1e-06 28.3 3.0 0.0099 16.5 0.1 4.0 3 2 2 5 5 5 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD19611.1 - 1.1e-05 25.4 0.6 0.0062 16.5 0.0 2.7 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD19611.1 - 0.0029 17.0 1.2 0.069 12.5 0.4 2.4 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein AlkA_N PF06029.11 PVD19611.1 - 0.021 15.1 0.1 0.091 13.0 0.0 2.1 2 0 0 2 2 2 0 AlkA N-terminal domain VWA PF00092.28 PVD19612.1 - 1.5e-34 119.7 0.0 1.8e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19612.1 - 3.5e-10 40.5 0.0 5.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD19612.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain adh_short PF00106.25 PVD19613.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 PVD19614.1 - 1.5e-11 44.1 0.0 1.7e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19614.1 - 2.3e-08 33.9 0.0 2.8e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19614.1 - 0.0017 18.3 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 PVD19614.1 - 0.075 12.0 0.0 0.075 12.0 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 PVD19615.1 - 2.1e-46 157.9 0.4 6.9e-23 81.1 0.0 3.2 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19615.1 - 5.1e-27 94.9 0.2 8.2e-14 51.7 0.0 2.9 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Peptidase_S8 PF00082.22 PVD19616.1 - 9.2e-46 156.4 3.0 1.2e-45 156.0 3.0 1.2 1 0 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 PVD19616.1 - 5.8e-21 75.1 0.9 1.2e-20 74.0 0.9 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain P_proprotein PF01483.20 PVD19616.1 - 1.7e-20 72.8 0.1 5.4e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain PPL5 PF18168.1 PVD19616.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Prim-pol family 5 adh_short PF00106.25 PVD19618.1 - 1.7e-46 158.2 0.0 2.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19618.1 - 2.6e-36 125.4 0.1 3.5e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19618.1 - 1.3e-07 31.7 0.1 2.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD19618.1 - 0.0021 17.5 0.2 0.0043 16.6 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD19618.1 - 0.0031 17.0 0.2 0.0055 16.1 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 PVD19618.1 - 0.0058 15.7 0.5 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 PVD19618.1 - 0.066 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 PVD19618.1 - 0.077 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family MEA1 PF06910.11 PVD19619.1 - 5 7.8 9.9 0.95 10.1 1.4 2.2 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) DUF1772 PF08592.11 PVD19620.1 - 0.06 13.7 0.6 0.069 13.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DHHC PF01529.20 PVD19620.1 - 0.093 12.8 1.3 0.12 12.5 1.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF5472 PF17566.2 PVD19620.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5472) adh_short PF00106.25 PVD19621.1 - 2.2e-46 157.8 0.1 3.3e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19621.1 - 1.7e-36 125.9 0.1 2.3e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19621.1 - 9.1e-08 32.2 0.1 1.9e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 PVD19621.1 - 0.0029 17.0 0.2 0.0056 16.1 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD19621.1 - 0.0038 16.7 1.1 0.0053 16.3 0.1 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD19621.1 - 0.0056 15.7 0.5 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 PVD19621.1 - 0.073 12.6 0.4 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 PVD19621.1 - 0.098 12.5 0.7 0.16 11.8 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain eIF-3c_N PF05470.12 PVD19622.1 - 1.1 7.4 19.0 0.24 9.6 13.7 2.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus adh_short PF00106.25 PVD19623.1 - 4.6e-41 140.4 0.1 9.1e-41 139.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19623.1 - 2.5e-27 96.0 0.1 3.4e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19623.1 - 2.3e-05 24.4 0.2 3.2e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PVD19624.1 - 3.4e-45 153.9 0.0 6.1e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19624.1 - 1e-32 113.6 0.0 1.5e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19624.1 - 1.6e-06 28.1 0.1 2.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 KR domain HTH_Tnp_Tc5 PF03221.16 PVD19624.1 - 0.003 17.5 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Epimerase PF01370.21 PVD19624.1 - 0.013 15.0 0.1 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CENP-B_N PF04218.13 PVD19624.1 - 0.014 15.0 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 PVD19624.1 - 0.11 12.4 0.1 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 PVD19624.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Transposase adh_short PF00106.25 PVD19625.1 - 4.3e-12 45.9 0.1 5.2e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19625.1 - 7.1e-08 32.3 0.1 8e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19625.1 - 0.0013 18.7 0.1 0.0015 18.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Nucleotid_trans PF03407.16 PVD19625.1 - 0.047 13.7 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase NAS PF03059.16 PVD19625.1 - 0.063 12.6 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Nicotianamine synthase protein RRM_occluded PF16842.5 PVD19625.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif adh_short PF00106.25 PVD19626.1 - 4.3e-28 98.1 0.1 3.3e-27 95.2 0.0 2.4 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19626.1 - 5.3e-21 75.3 0.0 1.2e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19626.1 - 6.6e-05 22.9 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 KR domain RRM_occluded PF16842.5 PVD19626.1 - 0.095 12.6 0.1 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif adh_short PF00106.25 PVD19627.1 - 9.5e-27 93.7 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19627.1 - 2.3e-18 66.6 0.1 3.3e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD19628.1 - 6.1e-45 153.1 0.0 1e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19628.1 - 6.9e-35 120.7 0.1 9.1e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19628.1 - 3.5e-08 33.6 0.1 5.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD19628.1 - 0.11 11.9 0.4 0.3 10.5 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.21 PVD19629.1 - 2.2e-71 240.5 0.0 2.5e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 PVD19630.1 - 2.5e-33 115.2 0.0 4.3e-33 114.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19630.1 - 6.1e-20 71.8 0.0 8.2e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19630.1 - 0.0013 18.7 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 KR domain RRM_occluded PF16842.5 PVD19630.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif adh_short PF00106.25 PVD19631.1 - 8.6e-68 227.7 0.3 1.6e-39 135.4 0.0 3.9 3 1 2 5 5 5 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD19631.1 - 2.5e-50 171.2 0.1 6.9e-28 97.8 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD19631.1 - 1.9e-16 60.5 0.1 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 PVD19631.1 - 3e-05 23.6 1.7 0.006 16.1 0.1 2.6 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD19631.1 - 0.0012 18.0 0.7 0.21 10.6 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PVD19631.1 - 0.0022 17.5 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RRM_occluded PF16842.5 PVD19631.1 - 0.0035 17.2 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF3048_C PF17479.2 PVD19631.1 - 0.13 12.7 0.3 3.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Ig_3 PF13927.6 PVD19635.1 - 9.7e-13 48.5 0.0 5.6e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD19635.1 - 1.3e-10 41.3 0.1 2.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19635.1 - 2.8e-10 40.1 0.0 4.9e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD19635.1 - 9.7e-10 38.6 0.0 0.0026 17.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19635.1 - 5.6e-08 33.0 0.1 0.00031 21.0 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD19635.1 - 7.2e-06 25.5 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 PVD19635.1 - 0.00011 22.4 0.1 1.1 9.5 0.0 3.1 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD19635.1 - 0.00053 20.3 0.1 0.18 12.2 0.1 3.0 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD19635.1 - 0.0093 16.0 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 PVD19635.1 - 0.053 13.9 0.1 7 7.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain TrmO PF01980.16 PVD19637.1 - 5.3e-45 152.5 0.0 7.6e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O MFS_1 PF07690.16 PVD19638.1 - 4.3e-36 124.6 31.7 2.2e-30 105.8 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD19638.1 - 5.3e-27 94.8 27.2 5.4e-16 58.5 4.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 PVD19639.1 - 4.8e-13 48.8 24.4 1e-07 31.2 6.4 2.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD19639.1 - 4.3e-09 35.8 35.2 5.5e-08 32.1 16.3 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily zf-RNPHF PF08080.12 PVD19639.1 - 0.099 12.6 0.2 22 5.1 0.1 2.6 2 0 0 2 2 2 0 RNPHF zinc finger TraP PF07296.11 PVD19640.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 TraP protein MFS_1 PF07690.16 PVD19641.1 - 6.1e-11 41.8 3.0 7.5e-11 41.5 3.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD19641.1 - 4.5e-06 25.8 0.0 4.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 PVD19641.1 - 5.4e-05 21.9 1.2 7.1e-05 21.5 1.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein PX PF00787.24 PVD19642.1 - 1.2e-20 73.5 1.9 1.4e-20 73.4 0.3 1.8 2 0 0 2 2 2 1 PX domain PDZ PF00595.24 PVD19642.1 - 1.1e-16 61.0 0.8 2.1e-16 60.1 0.8 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD19642.1 - 2.4e-15 56.1 0.3 5.3e-15 55.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain RA PF00788.23 PVD19642.1 - 7.6e-12 45.7 0.2 1.9e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 PVD19642.1 - 4.6e-06 26.9 0.1 1.3e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.10 PVD19642.1 - 0.077 12.9 0.0 0.22 11.5 0.0 1.9 1 1 0 1 1 1 0 FERM N-terminal domain Tricorn_PDZ PF14685.6 PVD19642.1 - 0.081 12.9 0.6 3.8 7.6 0.2 2.6 1 1 1 2 2 2 0 Tricorn protease PDZ domain SNX17_FERM_C PF18116.1 PVD19642.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain Ank_5 PF13857.6 PVD19643.1 - 1.5e-23 82.5 1.7 2.9e-10 40.2 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD19643.1 - 3.7e-18 65.6 0.4 6.8e-09 36.1 0.1 3.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 PVD19643.1 - 4.2e-18 64.7 0.0 8.9e-18 63.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 PVD19643.1 - 5.3e-18 65.4 0.1 1.6e-17 63.9 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD19643.1 - 3.9e-15 55.5 0.2 3.2e-06 27.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 PVD19643.1 - 1.3e-14 53.8 0.1 2.1e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 PVD19643.1 - 1.4e-11 43.5 0.1 0.0024 18.2 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat SH3_2 PF07653.17 PVD19643.1 - 9.9e-10 38.0 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 PVD19643.1 - 0.057 13.5 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 SH3 domain MutS_V PF00488.21 PVD19644.1 - 1.1e-68 231.0 0.1 3.9e-68 229.2 0.1 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PVD19644.1 - 2e-34 119.5 2.0 2e-34 119.5 2.0 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PVD19644.1 - 4.4e-31 107.4 0.0 9.7e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PVD19644.1 - 2.1e-17 63.7 0.1 7.6e-17 61.9 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 PVD19644.1 - 7.9e-06 26.1 0.1 2.5e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV DUF1241 PF06840.11 PVD19644.1 - 0.096 12.3 0.1 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Focal_AT PF03623.13 PVD19644.1 - 0.1 12.6 0.5 0.45 10.5 0.3 1.9 1 1 0 1 1 1 0 Focal adhesion targeting region SOBP PF15279.6 PVD19644.1 - 0.77 10.3 9.7 1.5 9.3 9.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein RIIa PF02197.17 PVD19645.1 - 0.00018 21.1 0.0 0.00038 20.1 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Sugar_tr PF00083.24 PVD19647.1 - 0.0025 16.7 0.1 0.003 16.5 0.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD19647.1 - 0.004 16.1 5.5 0.004 16.1 5.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3413 PF11893.8 PVD19647.1 - 0.012 14.8 0.7 0.029 13.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) MerC PF03203.14 PVD19647.1 - 0.12 12.8 2.7 0.15 12.6 0.2 2.0 2 0 0 2 2 2 0 MerC mercury resistance protein Sugar_tr PF00083.24 PVD19648.1 - 1.3e-08 34.2 5.8 1.5e-08 34.0 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD19648.1 - 2.6e-08 33.2 5.7 2.9e-08 33.0 5.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FhuF_C PF11575.8 PVD19648.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Phage_holin_3_2 PF04550.12 PVD19648.1 - 0.38 11.3 3.9 1.4 9.5 3.9 1.9 1 1 0 1 1 1 0 Phage holin family 2 DUF751 PF05421.11 PVD19648.1 - 2.6 8.8 5.5 1.4 9.7 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF751) Hormone_recep PF00104.30 PVD19649.1 - 3.8e-28 98.5 0.0 5.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD19649.1 - 3.2e-14 53.1 1.8 7.1e-14 52.0 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Mito_carr PF00153.27 PVD19650.1 - 1.4e-05 24.9 0.6 0.85 9.6 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein C1q PF00386.21 PVD19651.1 - 9.4e-14 51.7 0.2 1.8e-13 50.8 0.0 1.5 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 PVD19651.1 - 0.0035 17.2 0.1 0.0063 16.4 0.1 1.4 1 0 0 1 1 1 1 BclA C-terminal domain ZapB PF06005.12 PVD19651.1 - 0.016 15.6 0.1 0.026 15.0 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 PVD19651.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF1192 PF06698.11 PVD19651.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) C1q PF00386.21 PVD19652.1 - 3.9e-14 52.9 0.0 6.2e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD19652.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Fer4_24 PF18109.1 PVD19653.1 - 1.9 8.9 6.5 24 5.3 0.2 4.8 4 0 0 4 4 4 0 Ferredoxin I 4Fe-4S cluster domain TPR_MLP1_2 PF07926.12 PVD19654.1 - 0.0034 17.5 29.6 0.0034 17.5 29.6 4.7 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 PVD19654.1 - 10 6.5 24.5 1.1 9.5 4.5 3.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) FixH PF05751.11 PVD19655.1 - 0.069 13.2 0.1 0.3 11.1 0.1 2.1 1 0 0 1 1 1 0 FixH Get5_bdg PF16843.5 PVD19656.1 - 0.032 13.7 0.0 4.2 7.0 0.0 2.0 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein PTN_MK_C PF01091.18 PVD19661.1 - 0.029 14.8 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain RVT_1 PF00078.27 PVD19664.1 - 7e-15 55.1 0.6 1.2e-14 54.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MADF_DNA_bdg PF10545.9 PVD19664.1 - 0.062 13.6 5.4 0.075 13.4 0.6 3.1 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_C33 PF05412.12 PVD19665.1 - 0.086 12.9 0.3 5.9 7.0 0.2 2.2 1 1 1 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase SEFIR PF08357.11 PVD19665.1 - 0.096 13.0 0.7 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 SEFIR domain Prok-RING_2 PF14445.6 PVD19666.1 - 0.49 10.6 4.2 7.4 6.8 0.6 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-C6H2 PF15801.5 PVD19666.1 - 7.8 6.9 6.9 1.5 9.2 3.1 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PLAT PF01477.23 PVD19669.1 - 4.2e-15 56.3 0.0 7.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 PVD19669.1 - 0.0082 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) PLAT PF01477.23 PVD19673.1 - 8.6e-17 61.8 0.1 1e-16 61.5 0.1 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 PVD19673.1 - 0.049 13.6 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) CYLD_phos_site PF16607.5 PVD19675.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured DUF1822 PF08852.11 PVD19675.1 - 0.26 10.3 5.6 0.36 9.8 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Exonuc_VII_L PF02601.15 PVD19675.1 - 0.33 10.5 5.2 0.48 10.0 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit I-set PF07679.16 PVD19680.1 - 1.7e-29 101.7 0.0 2.4e-16 59.6 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19680.1 - 3.5e-27 94.8 2.6 4e-13 49.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD19680.1 - 4.1e-17 62.3 0.4 1.2e-07 32.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD19680.1 - 4.6e-16 58.8 0.4 2.3e-10 40.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD19680.1 - 5.7e-13 49.0 3.3 0.00054 20.1 0.1 4.5 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD19680.1 - 0.0046 17.0 0.2 1.6 8.9 0.0 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD19680.1 - 0.0093 16.3 0.0 1.7 9.1 0.0 2.8 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD19680.1 - 0.04 14.0 0.0 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 PVD19680.1 - 0.14 12.4 0.0 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Glyco_hydro_10 PF00331.20 PVD19682.1 - 7.9e-27 94.2 0.0 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C3 PF18463.1 PVD19682.1 - 2.2e-09 37.4 10.8 6.7e-05 23.0 1.1 2.6 1 1 1 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Peptidase_C23 PF05379.11 PVD19682.1 - 0.011 15.8 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 0 Carlavirus endopeptidase PCSK9_C2 PF18464.1 PVD19682.1 - 0.1 12.6 1.9 0.28 11.2 0.1 2.7 3 0 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Glyco_hydro_10 PF00331.20 PVD19685.1 - 8.2e-27 94.2 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C3 PF18463.1 PVD19685.1 - 0.0039 17.4 0.3 0.0039 17.4 0.3 2.7 3 0 0 3 3 3 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain DUF4729 PF15866.5 PVD19686.1 - 0.0071 15.7 0.3 0.0095 15.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4729) Glyco_hydro_10 PF00331.20 PVD19687.1 - 1e-19 70.9 0.0 7.4e-11 41.8 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 PCSK9_C3 PF18463.1 PVD19687.1 - 0.00085 19.5 14.3 0.0009 19.4 8.8 3.1 2 1 1 3 3 3 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C1 PF18459.1 PVD19687.1 - 0.00091 19.3 9.0 0.0048 17.0 5.9 3.0 2 1 1 3 3 3 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain zf-C2HC5 PF06221.13 PVD19692.1 - 3.8e-11 42.8 10.5 7.2e-11 41.9 10.5 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.14 PVD19692.1 - 9.3e-06 26.2 0.0 4.9e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 ASCH domain MMU163 PF17119.5 PVD19692.1 - 0.59 9.2 2.9 0.33 10.1 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis TPR_12 PF13424.6 PVD19693.1 - 4.5e-09 36.5 11.8 0.0025 18.0 0.3 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD19693.1 - 0.00014 21.6 1.5 0.2 11.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19693.1 - 0.0012 18.8 15.9 0.049 13.8 0.3 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19693.1 - 0.0035 17.1 15.6 0.16 11.8 0.4 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19693.1 - 0.03 15.0 0.2 0.62 10.8 0.2 3.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Prefoldin PF02996.17 PVD19693.1 - 0.033 14.1 3.4 0.24 11.3 0.1 3.1 2 0 0 2 2 2 0 Prefoldin subunit HBM PF16591.5 PVD19693.1 - 0.3 10.5 5.5 0.9 8.9 0.1 3.0 4 0 0 4 4 4 0 Helical bimodular sensor domain TPR_8 PF13181.6 PVD19693.1 - 0.41 11.0 15.9 1.9 8.9 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3668 PF12416.8 PVD19694.1 - 7.3e-78 261.5 0.0 7.3e-78 261.5 0.0 2.4 3 0 0 3 3 3 1 Cep120 protein C2 PF00168.30 PVD19694.1 - 3.2e-07 30.6 0.0 0.0018 18.5 0.0 3.5 3 0 0 3 3 3 2 C2 domain DUF4497 PF14924.6 PVD19694.1 - 0.025 15.0 0.0 0.92 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Pkinase_fungal PF17667.1 PVD19695.1 - 0.043 12.6 0.2 0.078 11.7 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 PVD19696.1 - 2.2e-20 72.6 13.2 1.5e-08 35.1 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat WD40_like PF17005.5 PVD19696.1 - 6.1e-06 25.8 0.0 0.12 11.7 0.0 3.7 1 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 PVD19696.1 - 7.1e-06 26.2 0.0 0.26 11.6 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Flg_hook PF02120.16 PVD19696.1 - 0.042 13.7 0.3 0.34 10.8 0.3 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK PCSK9_C1 PF18459.1 PVD19697.1 - 2e-16 59.9 17.3 4.5e-10 39.5 4.0 3.4 2 1 1 3 3 3 3 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Glyco_hydro_10 PF00331.20 PVD19697.1 - 3.5e-11 42.8 4.5 3.6e-10 39.5 4.3 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 10 PCSK9_C3 PF18463.1 PVD19697.1 - 0.076 13.2 21.4 0.053 13.8 4.8 3.5 1 1 2 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Cu-oxidase_3 PF07732.15 PVD19698.1 - 8.3e-39 132.3 0.3 2.5e-38 130.7 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 PVD19698.1 - 7.3e-27 94.4 0.1 3.2e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD19698.1 - 5.4e-15 55.3 1.3 3.3e-11 43.1 0.0 3.0 2 1 0 2 2 2 2 Multicopper oxidase Phospholip_A2_1 PF00068.19 PVD19698.1 - 9.9 6.7 11.4 0.31 11.5 0.6 2.3 2 0 0 2 2 2 0 Phospholipase A2 ETF PF01012.21 PVD19699.1 - 6.7e-42 143.4 2.3 1.5e-41 142.3 2.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Cu2_monoox_C PF03712.15 PVD19699.1 - 1.8e-39 134.8 0.0 3.1e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain ETF_alpha PF00766.19 PVD19699.1 - 5.8e-23 80.7 0.1 2.6e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Cu2_monooxygen PF01082.20 PVD19699.1 - 1e-21 77.5 0.4 2e-21 76.6 0.4 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain PINIT PF14324.6 PVD19700.1 - 8.3e-38 130.0 0.0 1.4e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 PVD19700.1 - 3.1e-21 74.8 5.3 5.4e-21 74.1 5.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PVD19700.1 - 0.00012 21.8 2.0 0.00023 20.9 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Forkhead PF00250.18 PVD19701.1 - 1.5e-34 118.1 0.0 2.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain MRC1 PF09444.10 PVD19701.1 - 0.037 14.5 0.2 0.056 14.0 0.2 1.2 1 0 0 1 1 1 0 MRC1-like domain WD40 PF00400.32 PVD19702.1 - 6.4e-11 42.6 8.8 0.3 12.0 0.0 6.8 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD19702.1 - 6.6e-06 26.3 0.1 7.4 6.9 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain tify PF06200.14 PVD19702.1 - 0.14 11.5 2.1 3.5 7.0 0.2 3.0 3 0 0 3 3 3 0 tify domain Nnf1 PF03980.14 PVD19703.1 - 3.2e-07 30.7 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Nnf1 PKcGMP_CC PF16808.5 PVD19703.1 - 0.11 12.4 1.0 0.24 11.3 1.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase His_Me_b4a2 PF18275.1 PVD19703.1 - 0.2 11.8 2.9 4.1 7.6 0.0 2.7 3 0 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain SRF-TF PF00319.18 PVD19704.1 - 8e-12 44.5 0.2 1.4e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 PVD19704.1 - 3.7e-05 23.7 2.8 4.6e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat DUF4116 PF13475.6 PVD19704.1 - 0.083 12.6 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Nucleo_P87 PF07267.11 PVD19704.1 - 0.42 9.4 3.7 3.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF4611 PF15387.6 PVD19704.1 - 3.5 7.9 8.1 6.3 7.1 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SRF-TF PF00319.18 PVD19705.1 - 4.2e-11 42.1 0.1 6.5e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PI3Ka PF00613.20 PVD19706.1 - 2.4e-58 196.6 0.9 4.3e-58 195.8 0.9 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PVD19706.1 - 1.3e-49 169.3 0.3 2.3e-34 119.4 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 PVD19706.1 - 2.4e-34 118.2 0.0 9.7e-33 113.0 0.0 2.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 PVD19706.1 - 0.00074 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) C2 PF00168.30 PVD19706.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain Ion_trans PF00520.31 PVD19707.1 - 2.7e-06 26.8 2.8 9.5e-06 25.0 3.4 1.6 1 1 1 2 2 2 1 Ion transport protein DUF5336 PF17270.2 PVD19707.1 - 0.00039 20.1 2.0 0.0071 16.0 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5336) bZIP_1 PF00170.21 PVD19707.1 - 0.0011 19.1 7.4 0.0027 17.8 7.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF1664 PF07889.12 PVD19707.1 - 0.012 15.6 3.2 0.025 14.6 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 PVD19707.1 - 0.015 15.0 5.9 0.035 13.9 5.9 1.6 1 0 0 1 1 1 0 Septum formation initiator DASH_Spc19 PF08287.11 PVD19707.1 - 0.024 14.5 4.5 0.024 14.5 4.5 1.9 2 0 0 2 2 2 0 Spc19 DUF16 PF01519.16 PVD19707.1 - 0.054 14.0 5.8 0.13 12.8 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.11 PVD19707.1 - 0.33 9.8 8.9 0.4 9.5 7.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.15 PVD19707.1 - 0.84 9.8 8.4 2.7 8.2 8.4 1.8 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 PVD19707.1 - 1.4 9.4 11.3 0.096 13.1 5.9 1.8 2 0 0 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 PVD19707.1 - 2 6.2 6.6 0.27 9.1 1.6 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMIE PF16038.5 PVD19707.1 - 2.3 8.1 7.3 5.2 7.0 0.1 3.0 2 1 0 2 2 2 0 TMIE protein DUF724 PF05266.14 PVD19707.1 - 3.6 7.4 11.5 0.17 11.7 5.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) OTU PF02338.19 PVD19708.1 - 9.7e-13 48.7 0.1 3.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease zf-A20 PF01754.16 PVD19708.1 - 1.3e-07 31.4 4.4 3.4e-07 30.1 4.4 1.8 1 0 0 1 1 1 1 A20-like zinc finger TAP_C PF03943.13 PVD19708.1 - 0.0043 16.7 0.1 0.0099 15.5 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain Rbsn PF11464.8 PVD19708.1 - 0.1 12.3 0.1 0.36 10.6 0.1 2.0 1 0 0 1 1 1 0 Rabenosyn Rab binding domain UBA_4 PF14555.6 PVD19708.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Prenyltrans PF00432.21 PVD19709.1 - 2.2e-28 97.7 6.5 2.8e-06 27.0 0.0 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat ig PF00047.25 PVD19710.1 - 1.3e-14 54.1 0.1 3.9e-08 33.4 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19710.1 - 2.5e-14 53.1 0.1 4.7e-10 39.4 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19710.1 - 2.1e-13 50.7 0.0 7.7e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19710.1 - 6.7e-09 35.9 0.0 2.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19710.1 - 1.5e-06 28.5 0.0 0.0006 20.1 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 PVD19710.1 - 9e-05 22.0 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19710.1 - 0.02 14.9 0.1 5.8 7.1 0.0 2.8 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain DC_STAMP PF07782.13 PVD19712.1 - 8e-56 188.9 0.0 2.8e-55 187.1 0.0 2.0 1 0 0 1 1 1 1 DC-STAMP-like protein DAGK_prokar PF01219.19 PVD19712.1 - 4.5 7.2 6.4 5 7.0 0.3 3.1 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase Thioredoxin PF00085.20 PVD19713.1 - 1.4e-69 230.5 0.2 8.1e-35 118.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PVD19713.1 - 2.7e-32 112.2 4.6 1.8e-27 96.4 4.4 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PVD19713.1 - 4.9e-10 39.8 0.9 0.0071 16.8 0.1 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 PVD19713.1 - 3e-08 33.1 0.4 5.5e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 PVD19713.1 - 1.6e-07 31.5 0.0 0.033 14.5 0.0 3.7 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 PVD19713.1 - 3.8e-06 27.0 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 PVD19713.1 - 4.1e-06 26.7 0.1 0.097 12.6 0.0 2.8 2 1 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 PVD19713.1 - 3.1e-05 23.5 0.0 0.03 13.7 0.0 2.6 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 PVD19713.1 - 6.7e-05 23.1 0.2 0.026 14.7 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin Redoxin PF08534.10 PVD19713.1 - 0.00073 19.3 0.1 2 8.1 0.0 2.9 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 PVD19713.1 - 0.013 15.5 0.1 9.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 PVD19713.1 - 0.024 14.5 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 PVD19713.1 - 0.044 14.0 1.3 5.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Glutaredoxin ADPRTs_Tse2 PF18648.1 PVD19713.1 - 0.08 13.0 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Tse2 ADP-ribosyltransferase toxins ETC_C1_NDUFA4 PF04800.12 PVD19714.1 - 1.8e-15 57.0 0.3 2.6e-15 56.4 0.1 1.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region Ig_J_chain PF15097.6 PVD19714.1 - 0.077 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin J chain Ank_2 PF12796.7 PVD19715.1 - 1.6e-46 156.8 4.7 5.9e-17 62.0 0.2 5.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD19715.1 - 1.7e-37 126.2 6.6 0.00017 21.9 0.1 8.9 8 1 1 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 PVD19715.1 - 2.9e-36 119.4 8.2 5.5e-05 23.3 0.0 9.9 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 PVD19715.1 - 3e-34 117.0 1.1 1.1e-10 41.9 0.2 7.5 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD19715.1 - 3.5e-30 103.7 7.2 5e-07 29.9 0.2 9.2 6 1 4 10 10 10 8 Ankyrin repeats (many copies) YfmQ PF10787.9 PVD19715.1 - 0.018 14.8 0.0 28 4.5 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group PH_16 PF17838.1 PVD19716.1 - 1.3e-33 115.4 0.5 3.3e-32 110.9 0.1 2.8 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 PVD19716.1 - 4.4e-33 115.1 2.3 4.4e-33 115.1 2.3 3.0 2 0 0 2 2 2 1 RhoGEF domain C1_1 PF00130.22 PVD19716.1 - 3.8e-06 26.7 7.4 1e-05 25.3 7.4 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 PVD19716.1 - 0.0051 17.3 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 PH domain FTCD_C PF04961.12 PVD19716.1 - 3 7.6 8.0 5.6 6.7 0.1 3.0 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase HTH_AsnC-type PF13404.6 PVD19717.1 - 0.076 12.9 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PAH PF02671.21 PVD19718.1 - 9.4e-06 25.7 0.0 3.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Paired amphipathic helix repeat TetR PF13972.6 PVD19718.1 - 0.17 11.6 0.4 0.45 10.2 0.1 1.7 1 1 1 2 2 2 0 Bacterial transcriptional repressor 7tm_1 PF00001.21 PVD19719.1 - 7.2e-10 38.6 17.2 7.9e-10 38.5 16.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD19719.1 - 1.6e-08 34.2 13.0 2.7e-06 26.9 13.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Sid-5 PF17204.3 PVD19719.1 - 0.044 13.9 1.9 0.6 10.3 0.1 2.4 2 0 0 2 2 2 0 Sid-5 family 7TM_GPCR_Srsx PF10320.9 PVD19719.1 - 0.047 13.1 14.6 0.28 10.5 14.6 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2799 PF10973.8 PVD19720.1 - 0.054 13.9 0.1 0.31 11.5 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) DUF3388 PF11868.8 PVD19721.1 - 0.0046 16.3 0.1 0.013 14.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3388) Phage_rep_org_N PF09681.10 PVD19721.1 - 0.56 10.1 2.7 8.2 6.4 0.2 2.4 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) COMM_domain PF07258.14 PVD19722.1 - 9.5e-20 70.5 0.3 9.5e-20 70.5 0.3 2.1 3 0 0 3 3 3 1 COMM domain DUF1798 PF08807.10 PVD19722.1 - 0.00066 19.8 1.1 0.0012 18.9 1.1 1.6 1 1 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) PspB PF06667.12 PVD19722.1 - 0.051 13.6 0.4 0.13 12.4 0.4 1.7 1 0 0 1 1 1 0 Phage shock protein B Rep_fac-A_C PF08646.10 PVD19722.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain ATP_bind_1 PF03029.17 PVD19723.1 - 2.4e-71 240.3 0.3 2.8e-71 240.1 0.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Glyco_hydro_10 PF00331.20 PVD19724.1 - 1.4e-31 109.8 0.1 2.1e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD19724.1 - 1.1e-11 45.2 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD19724.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Exo70 PF03081.15 PVD19724.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit RBP_receptor PF14752.6 PVD19725.1 - 0.0012 17.6 0.1 0.0013 17.4 0.1 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor RBP_receptor PF14752.6 PVD19726.1 - 1.2e-45 156.3 25.9 4.3e-30 104.9 22.8 2.6 1 1 1 2 2 2 2 Retinol binding protein receptor Sulfatase PF00884.23 PVD19727.1 - 7.4e-32 111.0 2.4 8.5e-28 97.6 0.2 2.3 2 0 0 2 2 2 2 Sulfatase MFS_1 PF07690.16 PVD19727.1 - 4.3e-29 101.5 39.9 4.6e-28 98.2 23.1 3.0 3 1 1 4 4 4 2 Major Facilitator Superfamily Sulfatase_C PF14707.6 PVD19727.1 - 4.7e-05 24.1 0.2 0.13 13.0 0.0 2.6 2 0 0 2 2 2 2 C-terminal region of aryl-sulfatase CitMHS PF03600.16 PVD19727.1 - 0.082 12.1 6.7 0.34 10.1 0.0 2.4 2 0 0 2 2 2 0 Citrate transporter Cu_amine_oxid PF01179.20 PVD19728.1 - 6.8e-99 331.6 0.1 8.8e-99 331.2 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 PVD19728.1 - 4e-09 36.6 0.0 1.1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 PVD19728.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.20 PVD19729.1 - 4.8e-97 325.5 0.0 5.8e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain CDI PF02234.19 PVD19729.1 - 0.028 14.6 0.6 0.081 13.1 0.1 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Cu_amine_oxidN2 PF02727.16 PVD19730.1 - 7.7e-09 35.7 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 PVD19730.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.20 PVD19731.1 - 1.7e-104 350.0 0.0 2.2e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 PVD19731.1 - 1e-10 41.7 0.0 2.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 PVD19731.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN3 PF02728.16 PVD19731.1 - 0.001 19.4 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain VWA PF00092.28 PVD19732.1 - 1.5e-24 87.2 2.2 7.7e-22 78.4 0.3 2.6 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD19732.1 - 2.8e-11 44.0 0.8 2e-09 38.1 0.4 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain 7tm_1 PF00001.21 PVD19734.1 - 6e-09 35.6 4.6 8.2e-09 35.2 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TB2_DP1_HVA22 PF03134.19 PVD19735.1 - 6.2e-30 102.9 9.1 6.2e-30 102.9 9.1 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF4047 PF13256.6 PVD19735.1 - 0.0075 16.5 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) PTPlike_phytase PF14566.6 PVD19735.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4512 PF14975.6 PVD19735.1 - 0.13 13.0 0.1 0.5 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) An_peroxidase PF03098.15 PVD19736.1 - 5.9e-110 368.3 0.7 7.4e-110 368.0 0.7 1.1 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 PVD19736.1 - 1.6e-22 80.3 0.0 4e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PVD19736.1 - 1.4e-17 64.0 15.6 3.2e-17 62.8 15.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PVD19736.1 - 3.1e-17 62.6 0.0 6.4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 PVD19736.1 - 1.7e-07 30.3 2.5 0.0011 18.3 1.4 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD19736.1 - 4.8e-07 29.5 1.6 0.00098 18.9 0.4 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 PVD19736.1 - 4.3e-06 27.1 2.1 3.1e-05 24.3 1.4 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD19736.1 - 2.7e-05 23.7 3.9 0.11 12.5 1.3 3.2 2 0 0 2 2 2 2 EF-hand domain NAD_binding_1 PF00175.21 PVD19736.1 - 0.016 15.9 0.0 0.044 14.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain rhaM PF05336.13 PVD19736.1 - 0.037 14.1 0.4 6.6 6.8 0.2 2.4 2 0 0 2 2 2 0 L-rhamnose mutarotase EF-hand_5 PF13202.6 PVD19736.1 - 0.056 13.0 2.1 0.15 11.6 0.7 2.3 2 0 0 2 2 2 0 EF hand RST PF12174.8 PVD19736.1 - 0.057 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain HTH_Crp_2 PF13545.6 PVD19736.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain YuiB PF14068.6 PVD19736.1 - 1 10.0 4.5 1.3 9.6 2.9 2.0 2 0 0 2 2 1 0 Putative membrane protein 7tm_1 PF00001.21 PVD19737.1 - 8.6e-15 54.8 5.3 1.3e-09 37.8 3.8 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD19737.1 - 0.00028 20.4 2.3 0.00053 19.4 0.3 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx NADH_u_ox_C PF12853.7 PVD19737.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit PDR_CDR PF06422.12 PVD19737.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter 7tm_1 PF00001.21 PVD19738.1 - 1.7e-08 34.1 9.2 2.1e-08 33.8 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD19738.1 - 0.0003 20.2 4.7 0.00038 19.8 4.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD19738.1 - 0.00083 19.1 5.5 0.001 18.8 5.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD19738.1 - 0.0011 18.4 6.8 0.0013 18.2 6.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF996 PF06195.13 PVD19738.1 - 1.4 9.2 6.1 19 5.5 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF996) 7tm_1 PF00001.21 PVD19739.1 - 0.0014 18.0 0.4 0.0021 17.5 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD19740.1 - 1.7e-08 34.1 10.2 2.2e-08 33.8 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19740.1 - 0.00096 18.8 6.7 0.00096 18.8 6.7 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD19740.1 - 0.019 14.2 7.9 0.027 13.7 7.9 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD19741.1 - 7.3e-07 28.8 16.7 0.00011 21.6 16.7 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19741.1 - 0.4 10.3 15.0 0.091 12.4 7.3 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD19742.1 - 1.3e-11 44.4 15.4 1.9e-11 43.8 15.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD19742.1 - 0.00014 21.6 9.4 0.013 15.1 7.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD19742.1 - 0.011 15.1 6.5 0.13 11.6 6.5 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3810 PF12725.7 PVD19742.1 - 1.1 8.5 3.7 5.7 6.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Glyco_transf_10 PF00852.19 PVD19743.1 - 5.1e-37 127.3 0.1 8.1e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD19743.1 - 3.6e-15 56.4 0.1 8.4e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Ion_trans PF00520.31 PVD19744.1 - 7.9e-30 103.9 3.6 7.9e-30 103.9 3.6 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans PF00520.31 PVD19745.1 - 2.1e-105 351.4 78.6 7.2e-46 156.4 17.6 4.2 3 1 1 4 4 4 4 Ion transport protein PKD_channel PF08016.12 PVD19745.1 - 3.3e-09 35.9 61.8 1.8e-06 26.9 8.8 6.6 5 1 0 5 5 5 4 Polycystin cation channel GPHH PF16905.5 PVD19745.1 - 7.9e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Rgp1 PF08737.10 PVD19747.1 - 8.9e-46 156.9 0.3 1.1e-21 77.5 0.1 2.2 1 1 1 2 2 2 2 Rgp1 EFF-AFF PF14884.6 PVD19747.1 - 0.071 11.2 0.2 0.11 10.6 0.2 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen DUF608 PF04685.13 PVD19748.1 - 3e-156 520.1 7.2 4e-156 519.7 7.2 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 PVD19748.1 - 1.4e-98 330.2 0.3 2e-98 329.7 0.3 1.2 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 PVD19748.1 - 3.9e-08 33.0 1.3 6.5e-08 32.2 1.3 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 PVD19748.1 - 0.00056 19.0 0.6 0.0019 17.2 0.6 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 PVD19748.1 - 0.017 13.9 0.2 0.027 13.2 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain TORC_M PF12885.7 PVD19749.1 - 1.1e-26 93.6 1.2 1.1e-26 93.6 1.2 2.5 2 1 0 2 2 2 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.7 PVD19749.1 - 2.1e-21 76.2 2.3 5e-21 75.0 2.3 1.7 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus TORC_N PF12884.7 PVD19749.1 - 7.8e-20 71.4 2.9 7.8e-20 71.4 2.9 3.9 5 0 0 5 5 5 1 Transducer of regulated CREB activity, N terminus Prot_ATP_OB_N PF17758.1 PVD19749.1 - 0.021 14.5 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain eIF3_subunit PF08597.10 PVD19750.1 - 2.2e-51 175.1 33.5 2.5e-51 175.0 33.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SPT6_acidic PF14632.6 PVD19750.1 - 0.056 14.0 1.6 0.056 14.0 1.6 2.9 2 1 0 2 2 2 0 Acidic N-terminal SPT6 DUF775 PF05603.12 PVD19750.1 - 1.8 8.1 5.4 1 8.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF775) AAA_2 PF07724.14 PVD19751.1 - 4.1e-35 121.4 0.0 8.3e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 PVD19751.1 - 6.7e-12 45.3 0.6 1.3e-11 44.4 0.1 1.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 PVD19751.1 - 2.8e-08 34.3 0.0 5.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MoaE PF02391.17 PVD19752.1 - 2.3e-37 127.7 0.4 2.9e-37 127.4 0.4 1.1 1 0 0 1 1 1 1 MoaE protein Oxidored_q6 PF01058.22 PVD19753.1 - 3.7e-14 52.7 0.1 4.3e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Yippee-Mis18 PF03226.14 PVD19755.1 - 1.6e-24 86.2 0.5 4.4e-24 84.7 0.5 1.8 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Lectin_C PF00059.21 PVD19755.1 - 0.00053 20.7 4.9 0.00086 20.0 0.2 3.0 3 1 0 3 3 3 1 Lectin C-type domain PAN_4 PF14295.6 PVD19755.1 - 0.056 13.4 3.4 2.8 7.9 0.7 2.9 2 0 0 2 2 2 0 PAN domain dUTPase PF00692.19 PVD19756.1 - 1.5e-46 157.2 0.0 1.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase Peptidase_M13_N PF05649.13 PVD19757.1 - 3e-82 277.3 0.0 5.4e-82 276.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD19757.1 - 6.7e-63 212.0 0.0 1.1e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 GAPT PF11770.8 PVD19757.1 - 0.073 12.9 0.4 0.2 11.5 0.3 1.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Lipase PF00151.19 PVD19758.1 - 1.8e-87 293.8 0.1 2.1e-87 293.6 0.1 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 PVD19758.1 - 0.00027 21.6 0.2 0.00034 21.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 PVD19758.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 PVD19758.1 - 0.016 14.5 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PVD19758.1 - 0.031 14.1 0.1 0.08 12.7 0.1 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Cu2_monoox_C PF03712.15 PVD19758.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Lipase PF00151.19 PVD19759.1 - 9.8e-60 202.6 0.0 1.4e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 PVD19759.1 - 0.11 12.2 0.2 0.32 10.6 0.1 1.8 1 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase PF00151.19 PVD19760.1 - 2e-61 208.2 0.0 2.5e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 PVD19760.1 - 0.00064 19.4 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD19760.1 - 0.0073 16.9 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD19760.1 - 0.013 14.8 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_2 PF01674.18 PVD19760.1 - 0.015 14.8 0.1 0.031 13.8 0.0 1.4 2 0 0 2 2 2 0 Lipase (class 2) Palm_thioest PF02089.15 PVD19760.1 - 0.023 14.6 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 PVD19760.1 - 0.041 13.7 0.1 0.088 12.6 0.1 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 PVD19760.1 - 0.19 11.6 0.3 0.67 9.8 0.3 1.8 1 1 0 1 1 1 0 Serine hydrolase Lipase PF00151.19 PVD19761.1 - 4e-25 88.8 1.9 4.4e-25 88.7 1.9 1.0 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 PVD19762.1 - 1.1e-93 314.2 0.0 1.3e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 PVD19762.1 - 0.00027 21.6 0.3 0.00039 21.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD19762.1 - 0.00078 18.8 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 PVD19762.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Palm_thioest PF02089.15 PVD19762.1 - 0.021 14.7 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PVD19762.1 - 0.022 14.4 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PVD19762.1 - 0.023 14.5 0.1 0.2 11.4 0.2 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 PVD19762.1 - 0.073 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Rod_C PF10493.9 PVD19763.1 - 1.1e-67 228.8 6.6 1.9e-50 171.8 1.1 3.4 1 1 2 3 3 3 3 Rough deal protein C-terminal region CSD PF00313.22 PVD19763.1 - 4.1e-18 65.0 0.3 3.4e-17 62.0 0.1 2.4 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PVD19763.1 - 0.028 14.1 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain RIO1 PF01163.22 PVD19764.1 - 5.4e-51 172.9 1.9 7e-51 172.5 0.2 2.0 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 PVD19764.1 - 9.4e-33 112.3 0.2 3.5e-32 110.4 0.2 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 PVD19764.1 - 1.3e-08 35.1 0.5 0.0062 16.5 0.3 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PVD19764.1 - 2.2e-08 33.7 1.6 0.00042 19.7 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PVD19764.1 - 0.0053 16.2 0.2 0.0053 16.2 0.2 2.0 2 1 0 2 2 2 1 Protein kinase domain LysM PF01476.20 PVD19765.1 - 0.0061 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF4686 PF15742.5 PVD19765.1 - 0.011 15.0 1.7 0.015 14.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) UPF0242 PF06785.11 PVD19765.1 - 0.051 13.7 0.7 0.076 13.1 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RNA_pol_3_Rpc31 PF11705.8 PVD19766.1 - 2.4e-34 119.6 10.8 2.4e-34 119.6 10.8 1.4 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2722 PF10846.8 PVD19766.1 - 0.059 12.3 5.1 0.069 12.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Astro_capsid_p PF12226.8 PVD19766.1 - 0.099 11.8 13.1 0.11 11.6 13.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 PVD19766.1 - 0.26 10.6 15.2 0.33 10.3 15.2 1.1 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 PVD19766.1 - 0.72 9.8 10.9 1 9.3 10.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 PVD19766.1 - 1.6 7.8 18.6 1.9 7.5 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Serinc PF03348.15 PVD19766.1 - 2.6 6.9 3.3 2.6 6.9 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 PVD19766.1 - 3.1 7.1 16.8 4.3 6.7 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 PVD19766.1 - 3.4 6.3 7.7 4.2 6.0 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RP-C_C PF11800.8 PVD19766.1 - 3.8 7.6 6.8 4.9 7.2 6.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4820 PF16091.5 PVD19766.1 - 4.3 6.6 7.5 6.3 6.1 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP_sp32 PF07222.12 PVD19766.1 - 5.1 6.5 10.4 6.2 6.2 10.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 E7 PF00527.18 PVD19766.1 - 6.9 6.9 10.6 16 5.8 10.6 1.6 1 0 0 1 1 1 0 E7 protein, Early protein FAM221 PF14753.6 PVD19767.1 - 1.3e-23 83.6 14.1 5.1e-13 49.0 3.9 2.1 2 0 0 2 2 2 2 Protein FAM221A/B DDE_1 PF03184.19 PVD19768.1 - 7.4e-34 116.9 0.0 1.5e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 PVD19768.1 - 1.6e-06 27.6 1.0 1.5e-05 24.5 0.2 2.4 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 PVD19768.1 - 0.00083 19.3 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 PVD19768.1 - 0.015 15.1 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 PVD19768.1 - 0.13 11.9 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1674 PF07896.12 PVD19769.1 - 5.8e-20 71.5 10.5 1.4e-19 70.3 10.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MIF4G_like_2 PF09090.11 PVD19770.1 - 4.2e-81 272.3 5.5 1e-80 271.1 5.5 1.6 1 0 0 1 1 1 1 MIF4G like ubiquitin PF00240.23 PVD19770.1 - 7.7e-67 221.0 7.6 2.1e-33 113.9 0.3 3.4 3 0 0 3 3 3 2 Ubiquitin family MIF4G_like PF09088.11 PVD19770.1 - 2.5e-33 115.4 0.8 2.5e-33 115.4 0.8 1.9 2 0 0 2 2 2 1 MIF4G like Rad60-SLD PF11976.8 PVD19770.1 - 5.5e-32 109.4 4.2 2.2e-15 56.2 0.4 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PVD19770.1 - 2.2e-11 44.1 1.5 0.00049 20.5 0.1 3.5 3 0 0 3 3 3 2 Ubiquitin-like domain MIF4G PF02854.19 PVD19770.1 - 2.6e-09 37.0 0.3 2.9e-05 23.8 0.0 3.1 2 1 1 3 3 3 2 MIF4G domain TBK1_ULD PF18396.1 PVD19770.1 - 7.5e-07 29.0 0.2 0.079 12.9 0.0 3.0 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PVD19770.1 - 2.1e-05 24.8 0.6 0.22 11.9 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PVD19770.1 - 2.4e-05 24.4 0.2 0.35 11.0 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2524 PF10732.9 PVD19770.1 - 7.3e-05 23.0 1.9 0.00039 20.7 1.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2524) DUF2407 PF10302.9 PVD19770.1 - 0.00028 21.4 0.1 1.1 9.8 0.0 2.7 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain DUF2046 PF09755.9 PVD19770.1 - 0.0013 18.0 1.2 0.0027 17.0 1.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) T3SSipB PF16535.5 PVD19770.1 - 0.068 13.6 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB Tropomyosin_1 PF12718.7 PVD19770.1 - 0.079 13.1 6.2 0.21 11.8 6.2 1.7 1 0 0 1 1 1 0 Tropomyosin like Uso1_p115_C PF04871.13 PVD19770.1 - 0.084 13.2 3.3 0.26 11.7 3.3 1.8 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ubiquitin_4 PF18036.1 PVD19770.1 - 0.17 11.9 6.5 86 3.3 0.0 4.5 4 0 0 4 4 4 0 Ubiquitin-like domain TPR_MLP1_2 PF07926.12 PVD19770.1 - 0.33 11.0 3.6 0.92 9.6 3.6 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TBCA PF02970.16 PVD19770.1 - 0.52 10.7 5.3 1.9 8.9 4.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Prefoldin PF02996.17 PVD19770.1 - 1.6 8.7 7.6 0.96 9.4 0.3 3.3 2 1 1 3 3 3 0 Prefoldin subunit FliJ PF02050.16 PVD19770.1 - 7.4 6.8 6.7 3.2 8.0 2.0 2.6 2 1 1 3 3 3 0 Flagellar FliJ protein ubiquitin PF00240.23 PVD19771.1 - 3.9e-105 343.7 12.3 3.1e-34 116.6 0.3 3.8 4 0 0 4 4 4 3 Ubiquitin family Rad60-SLD PF11976.8 PVD19771.1 - 1.7e-50 168.7 12.8 3.3e-16 58.9 0.4 3.4 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PVD19771.1 - 3.4e-20 72.3 3.3 7.9e-05 23.0 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 PVD19771.1 - 1.5e-12 47.2 1.7 0.016 15.1 0.1 3.3 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PVD19771.1 - 8e-12 45.2 0.7 0.048 13.8 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PVD19771.1 - 1.6e-11 44.4 2.7 0.033 14.5 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 PVD19771.1 - 3.4e-09 37.2 0.1 0.34 11.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 PVD19771.1 - 1.4e-06 28.2 0.0 1.4 8.7 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 PVD19771.1 - 7.2e-06 26.0 14.1 19 5.4 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain UDP-g_GGTase PF06427.11 PVD19771.1 - 0.00021 21.4 1.3 3.8 7.7 0.0 3.7 4 0 0 4 4 4 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 PVD19771.1 - 0.00029 21.2 0.0 22 5.5 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 PVD19771.1 - 0.00066 19.1 0.9 1.4 8.2 0.0 2.8 3 0 0 3 3 3 2 RNA methyltransferase RBD PF02196.15 PVD19771.1 - 0.00099 19.1 0.0 25 5.1 0.0 3.4 3 0 0 3 3 3 0 Raf-like Ras-binding domain DUF969 PF06149.12 PVD19771.1 - 0.0013 18.2 0.1 15 4.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 PVD19771.1 - 0.0023 18.0 0.4 24 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ORF11CD3 PF10549.9 PVD19771.1 - 0.0085 16.2 0.0 68 3.7 0.0 3.8 3 0 0 3 3 3 0 ORF11CD3 domain FlgD_ig PF13860.6 PVD19771.1 - 0.024 14.5 2.4 43 4.1 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Big_7 PF17957.1 PVD19771.1 - 0.026 15.3 0.0 99 3.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain GDYXXLXY PF14345.6 PVD19771.1 - 0.066 13.0 0.1 82 3.0 0.0 3.3 3 0 0 3 3 3 0 GDYXXLXY protein Phage_sheath_1N PF17481.2 PVD19771.1 - 0.07 13.6 1.3 20 5.7 0.2 3.0 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain CorA PF01544.18 PVD19771.1 - 0.077 12.3 0.1 57 2.9 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein TraK PF06586.11 PVD19771.1 - 0.09 12.5 0.1 66 3.1 0.0 3.1 3 0 0 3 3 3 0 TraK protein ProRS-C_2 PF09181.10 PVD19771.1 - 0.11 12.6 1.1 97 3.2 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal PI3K_p85B PF02192.16 PVD19771.1 - 1.6 8.5 3.4 1.2e+02 2.5 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Misat_Tub_SegII PF10644.9 PVD19772.1 - 1.9e-35 121.7 0.0 3.6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PVD19772.1 - 2.3e-16 60.0 0.0 4.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 PVD19772.1 - 2.8e-09 37.5 0.0 5.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PTPS PF01242.19 PVD19773.1 - 6.8e-23 81.0 0.2 7.7e-23 80.8 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase MACPF PF01823.19 PVD19774.1 - 4.7e-13 49.7 4.3 1.1e-12 48.5 4.3 1.5 1 1 0 1 1 1 1 MAC/Perforin domain DUF5329 PF17263.2 PVD19774.1 - 0.54 10.5 3.3 7.4 6.8 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5329) Branch PF02485.21 PVD19775.1 - 1.9e-16 60.3 0.0 2.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme NADH-u_ox-rdase PF10785.9 PVD19777.1 - 0.036 14.8 0.1 12 6.7 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit IL17R_D_N PF16742.5 PVD19778.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Gly_transf_sug PF04488.15 PVD19779.1 - 6.8e-13 49.1 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD19779.1 - 0.0014 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD19779.1 - 0.034 13.5 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain 7tm_1 PF00001.21 PVD19780.1 - 2e-38 132.3 11.7 2.6e-38 131.9 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD19780.1 - 8.3e-13 48.3 9.4 1.2e-12 47.8 9.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD19780.1 - 0.33 10.2 12.7 1.9 7.7 12.7 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD19780.1 - 2 8.0 14.6 0.072 12.7 8.6 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Rav1p_C PF12234.8 PVD19781.1 - 9.7e-37 126.7 8.0 3.2e-20 72.1 2.5 4.5 3 1 1 4 4 4 4 RAVE protein 1 C terminal WD40 PF00400.32 PVD19781.1 - 9.5e-18 64.3 20.2 0.019 15.8 0.0 11.2 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD19781.1 - 9.4e-05 22.6 0.0 0.69 10.3 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PTE PF02126.18 PVD19781.1 - 0.099 12.1 0.2 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotriesterase family Bcl-2 PF00452.19 PVD19782.1 - 4.3e-14 53.0 0.5 8.1e-14 52.1 0.5 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Luteo_P1-P2 PF08467.10 PVD19782.1 - 0.041 13.1 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase 7tm_1 PF00001.21 PVD19784.1 - 3.6e-06 26.5 4.5 4.2e-06 26.3 4.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) E1_DerP2_DerF2 PF02221.15 PVD19785.1 - 4e-09 37.0 0.7 5.8e-09 36.5 0.7 1.3 1 0 0 1 1 1 1 ML domain Peptidase_S8 PF00082.22 PVD19786.1 - 2.2e-47 161.8 0.1 3.1e-47 161.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 PVD19786.1 - 1.3e-26 92.4 0.0 2.5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 PVD19786.1 - 9.6e-13 48.7 1.6 1.9e-12 47.8 1.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain VSP PF03302.13 PVD19786.1 - 8.6e-09 34.7 28.2 2.6e-06 26.5 12.9 2.4 1 1 1 2 2 2 2 Giardia variant-specific surface protein Furin-like PF00757.20 PVD19786.1 - 0.053 13.4 39.7 0.015 15.2 31.5 3.3 1 1 1 2 2 2 0 Furin-like cysteine rich region Stevor PF17410.2 PVD19786.1 - 0.071 12.7 0.7 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD99L2 PF12301.8 PVD19786.1 - 0.18 12.1 0.1 0.71 10.2 0.0 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 PHR PF08005.12 PVD19787.1 - 9.9e-46 156.2 0.9 2.3e-45 154.9 0.9 1.6 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 PVD19787.1 - 3.3e-26 91.7 0.3 1.1e-24 86.8 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD19787.1 - 9.9e-10 38.5 0.3 1e-08 35.2 0.2 2.5 1 1 1 2 2 2 1 BTB And C-terminal Kelch JTB PF05439.12 PVD19788.1 - 5.6e-19 68.2 2.4 7.7e-19 67.8 2.4 1.2 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Cu_amine_oxid PF01179.20 PVD19789.1 - 2.8e-96 322.9 3.8 2.2e-67 227.7 0.1 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 PVD19789.1 - 2e-06 27.9 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 PVD19789.1 - 0.046 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain PEX11 PF05648.14 PVD19790.1 - 1.6e-47 161.9 1.9 2.1e-47 161.5 1.9 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FAM124 PF15067.6 PVD19790.1 - 0.059 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM124 family GLTP PF08718.11 PVD19790.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Acetyltransf_1 PF00583.25 PVD19791.1 - 1.9e-17 63.6 0.0 3.4e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD19791.1 - 3.8e-13 49.5 0.1 6.6e-09 35.8 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD19791.1 - 8.5e-12 45.3 0.8 8.3e-11 42.2 0.8 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PVD19791.1 - 1.3e-06 28.5 0.1 0.00021 21.4 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PVD19791.1 - 3e-05 24.1 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 PVD19791.1 - 9.6e-05 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 PVD19791.1 - 0.0021 17.5 0.9 0.0086 15.6 0.9 1.9 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 PVD19791.1 - 0.03 15.0 0.0 0.062 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4110 PF13422.6 PVD19791.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Lipl32 PF12103.8 PVD19791.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 Surface lipoprotein of Spirochaetales order Mfa1 PF17445.2 PVD19795.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Mating factor A1 SMI1_KNR4 PF09346.10 PVD19797.1 - 0.0017 18.7 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RasGAP PF00616.19 PVD19798.1 - 1.2e-28 100.2 0.8 2.5e-23 82.9 0.1 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase SH2 PF00017.24 PVD19798.1 - 3.2e-17 62.4 0.2 1.6e-14 53.8 0.1 2.7 2 0 0 2 2 2 2 SH2 domain PH PF00169.29 PVD19798.1 - 1.3e-14 54.6 0.2 3.5e-14 53.2 0.2 1.8 1 0 0 1 1 1 1 PH domain C2 PF00168.30 PVD19798.1 - 1.8e-11 44.2 0.0 3.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 PVD19798.1 - 3.3e-09 36.2 0.0 5.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD19798.1 - 4.9e-09 35.9 0.0 9.8e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD19798.1 - 6.4e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4554 PF15091.6 PVD19798.1 - 0.087 11.7 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DENN PF02141.21 PVD19799.1 - 6.1e-60 202.4 2.7 1.1e-59 201.5 2.7 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PVD19799.1 - 1.7e-17 63.9 1.6 4.1e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 PVD19799.1 - 5.2e-14 52.0 7.6 1.4e-13 50.6 7.6 1.8 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 PVD19799.1 - 2.4e-05 24.4 0.0 6.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 PVD19799.1 - 0.00022 21.2 0.1 0.00055 19.9 0.1 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain Iso_dh PF00180.20 PVD19800.1 - 6.6e-101 337.9 0.0 7.4e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF758 PF05527.11 PVD19801.1 - 3e-70 235.9 2.1 4e-70 235.5 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF4065 PF13274.6 PVD19801.1 - 0.047 14.6 0.9 0.1 13.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Ribosomal_S6e PF01092.19 PVD19802.1 - 3.8e-60 201.4 1.2 7.5e-60 200.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e BRCT_3 PF18428.1 PVD19804.1 - 2e-29 101.6 2.1 3e-25 88.2 0.1 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD19804.1 - 3.6e-09 36.9 0.3 1.4e-06 28.6 0.0 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain 53-BP1_Tudor PF09038.10 PVD19804.1 - 7.7e-08 32.3 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor Tudor_3 PF18115.1 PVD19804.1 - 1e-07 31.7 0.0 3.9e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 PVD19804.1 - 1.7e-07 31.3 0.0 4.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT PF00533.26 PVD19804.1 - 3.3e-07 30.6 0.4 0.003 17.9 0.0 3.2 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 PVD19804.1 - 5.3e-07 29.5 0.2 1.7e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_2 PF18104.1 PVD19804.1 - 2.5e-06 27.1 0.4 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 PVD19804.1 - 0.017 14.8 0.1 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 PVD19804.1 - 0.02 15.0 0.0 0.095 12.8 0.0 2.2 1 0 0 1 1 1 0 SGF29 tudor-like domain Neur_chan_LBD PF02931.23 PVD19805.1 - 1.1e-66 224.4 2.9 1.6e-66 223.9 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19805.1 - 3e-41 142.0 0.0 5.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Lactamase_B_4 PF13691.6 PVD19805.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 tRNase Z endonuclease Neur_chan_LBD PF02931.23 PVD19806.1 - 2.5e-46 157.8 3.2 2.5e-46 157.8 3.2 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19806.1 - 7.5e-42 144.0 3.8 1.7e-40 139.6 3.8 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YhhN PF07947.14 PVD19806.1 - 0.062 12.9 4.9 0.062 12.9 3.6 1.6 1 1 0 1 1 1 0 YhhN family Macoilin PF09726.9 PVD19806.1 - 0.26 9.8 3.3 0.42 9.1 3.3 1.2 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 PVD19806.1 - 0.82 8.8 10.4 0.025 13.8 3.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_U4 PF03419.13 PVD19806.1 - 1.6 8.0 3.9 3.3 6.9 2.4 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Neur_chan_LBD PF02931.23 PVD19808.1 - 3.6e-66 222.7 0.3 4.6e-66 222.3 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19808.1 - 5.5e-35 121.6 0.7 7.2e-35 121.2 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MT PF12777.7 PVD19809.1 - 1.1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor RVT_1 PF00078.27 PVD19810.1 - 1.9e-09 37.4 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) INCENP_N PF12178.8 PVD19810.1 - 0.002 18.1 2.5 21 5.2 0.1 3.6 3 0 0 3 3 3 3 Chromosome passenger complex (CPC) protein INCENP N terminal Clr2_transil PF16761.5 PVD19810.1 - 1.1 10.1 3.3 1.7e+02 3.2 0.1 4.0 4 0 0 4 4 4 0 Transcription-silencing protein, cryptic loci regulator Clr2 Na_Ca_ex PF01699.24 PVD19811.1 - 1.6e-21 76.9 4.7 2.1e-21 76.5 4.7 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein VWA_2 PF13519.6 PVD19812.1 - 7.8e-14 52.2 0.0 5e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Bcl-2 PF00452.19 PVD19813.1 - 1.3e-23 83.5 0.0 2.6e-23 82.6 0.0 1.5 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family BILBO1_N PF18281.1 PVD19813.1 - 0.0052 17.2 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 BILBO1 N-terminal domain GCOM2 PF15328.6 PVD19814.1 - 1.8e-08 35.0 13.3 4.3e-08 33.8 13.3 1.8 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 DUF4866 PF16160.5 PVD19814.1 - 0.0068 15.8 0.4 0.026 13.9 0.1 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4866) MtN3_slv PF03083.16 PVD19815.1 - 6.9e-30 102.9 18.8 6.6e-16 58.1 1.6 2.3 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 PVD19815.1 - 0.017 14.9 0.0 0.017 14.9 0.0 4.2 4 1 1 5 5 5 0 PQ loop repeat PgaD PF13994.6 PVD19815.1 - 0.36 10.9 0.1 0.36 10.9 0.1 3.1 1 1 0 2 2 2 0 PgaD-like protein Bax1-I PF01027.20 PVD19815.1 - 3 7.6 23.1 3.7 7.3 15.9 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 PVD19815.1 - 4.6 5.4 18.3 6.2 5.0 18.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Flavoprotein PF02441.19 PVD19816.1 - 1e-48 165.1 0.0 1.2e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Abhydrolase_1 PF00561.20 PVD19817.1 - 0.00082 19.1 0.0 0.0018 17.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD19817.1 - 0.01 16.5 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PVD19817.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 PVD19817.1 - 0.04 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MT PF12777.7 PVD19818.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor NOG1_N PF17835.1 PVD19818.1 - 0.019 14.9 0.6 0.14 12.1 0.2 2.3 1 1 1 2 2 2 0 NOG1 N-terminal helical domain Rota_NSP4 PF01452.16 PVD19818.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein GTP_EFTU PF00009.27 PVD19820.1 - 2e-59 200.4 1.0 3.6e-59 199.6 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PVD19820.1 - 1.6e-13 50.5 0.0 1e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PVD19820.1 - 1.5e-10 41.3 0.0 2.5e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PVD19820.1 - 4.5e-09 36.3 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 PVD19820.1 - 9.7e-05 22.1 0.0 0.0021 17.8 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 PVD19820.1 - 0.0012 18.9 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PVD19820.1 - 0.05 12.7 0.2 0.46 9.6 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 PVD19820.1 - 0.14 12.0 0.3 0.78 9.6 0.1 2.4 3 0 0 3 3 3 0 RsgA GTPase PDZ PF00595.24 PVD19824.1 - 2.4e-40 136.7 2.2 2.4e-15 56.7 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 PVD19824.1 - 1.5e-25 88.8 1.8 9.3e-08 31.8 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PVD19824.1 - 2e-13 50.5 0.4 0.003 17.8 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 PVD19825.1 - 6.7e-08 32.8 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD19825.1 - 2.7e-05 23.9 0.0 8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PVD19826.1 - 4.7e-18 65.3 0.1 3.6e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD19826.1 - 6.7e-14 51.5 0.1 1.1e-05 25.2 0.0 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 PVD19826.1 - 3.5e-06 27.3 1.8 0.0034 17.7 0.0 3.2 3 1 0 3 3 3 2 PDZ domain PBP1_TM PF14812.6 PVD19827.1 - 0.34 11.3 3.1 0.76 10.2 3.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4224 PF13986.6 PVD19828.1 - 6.5e-05 22.7 0.3 91 3.1 0.0 6.1 3 2 6 10 10 10 6 Domain of unknown function (DUF4224) GPP34 PF05719.11 PVD19829.1 - 2.2e-61 207.4 0.3 2.9e-61 207.1 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Sigma70_ECF PF07638.11 PVD19829.1 - 0.24 11.3 3.1 0.53 10.1 0.0 2.5 2 1 1 3 3 3 0 ECF sigma factor Pox_L5 PF04872.13 PVD19830.1 - 0.088 12.7 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus L5 protein family SRCR PF00530.18 PVD19831.1 - 0 1217.2 186.6 6.4e-25 87.6 4.4 32.4 28 4 4 32 32 32 31 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD19831.1 - 2.2e-99 326.3 160.0 1.7e-10 41.3 1.7 31.3 29 3 2 31 31 31 29 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD19831.1 - 6.3e-42 142.6 75.1 2.5e-05 24.7 1.8 25.2 25 2 2 27 27 27 13 Hepsin, SRCR domain UBA PF00627.31 PVD19831.1 - 0.19 11.7 0.0 2.6 8.0 0.1 3.1 2 0 0 2 2 2 0 UBA/TS-N domain SKG6 PF08693.10 PVD19831.1 - 0.38 10.2 3.1 0.91 9.0 3.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YecR PF13992.6 PVD19831.1 - 9.2 6.7 64.3 6 7.2 0.0 19.6 25 1 0 25 25 25 0 YecR-like lipoprotein SRCR PF00530.18 PVD19832.1 - 8.5e-38 128.9 9.4 6.4e-21 74.7 1.4 2.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD19832.1 - 4.3e-13 49.6 7.5 3.1e-06 27.6 0.9 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD19832.1 - 6.9e-09 36.2 1.0 0.0042 17.6 0.1 2.2 2 0 0 2 2 2 2 Hepsin, SRCR domain YecR PF13992.6 PVD19832.1 - 0.0023 18.2 5.7 0.43 10.9 0.1 3.3 2 1 1 3 3 3 2 YecR-like lipoprotein LAMTOR5 PF16672.5 PVD19832.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 SRCR PF00530.18 PVD19833.1 - 1.1e-16 61.1 1.0 1.5e-16 60.7 1.0 1.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD19833.1 - 8.1e-05 23.1 0.6 0.00013 22.4 0.6 1.5 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD19833.1 - 0.012 16.1 1.7 0.016 15.8 1.7 1.3 1 1 0 1 1 1 0 Hepsin, SRCR domain Disaggr_repeat PF06848.11 PVD19833.1 - 0.015 15.0 0.2 0.019 14.7 0.2 1.1 1 0 0 1 1 1 0 Disaggregatase related repeat Ig_3 PF13927.6 PVD19834.1 - 8.3e-33 112.8 2.1 1.5e-11 44.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD19834.1 - 1.1e-31 108.7 0.8 6.2e-11 42.2 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD19834.1 - 2.1e-19 69.5 2.1 1.1e-06 28.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD19834.1 - 6e-17 61.7 1.9 8.1e-06 26.1 0.3 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD19834.1 - 4e-15 55.9 6.0 1.6e-05 25.1 0.2 5.3 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD19834.1 - 2.1e-05 24.5 0.2 0.029 14.4 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD19834.1 - 8.2e-05 22.6 0.1 0.00068 19.6 0.1 2.3 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 PVD19834.1 - 0.00078 19.8 1.2 0.41 11.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 PVD19834.1 - 0.004 16.9 0.1 0.61 9.9 0.0 2.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 PVD19834.1 - 0.0093 15.5 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain BTD PF09270.10 PVD19834.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Ig_3 PF13927.6 PVD19835.1 - 4.9e-32 110.4 0.7 1.1e-11 45.2 0.2 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD19835.1 - 1.8e-30 104.9 1.9 3.9e-10 39.6 0.1 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD19835.1 - 1.4e-18 67.0 3.0 2.1e-08 34.4 0.7 3.9 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD19835.1 - 3.5e-17 62.4 4.8 5e-05 23.4 0.3 3.7 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD19835.1 - 8e-15 55.0 2.5 3.1e-06 27.3 0.1 3.7 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD19835.1 - 0.00011 21.7 0.0 0.28 10.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19835.1 - 0.00025 21.0 0.8 0.0015 18.5 0.0 2.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD19835.1 - 0.016 15.0 1.3 0.38 10.6 0.2 3.1 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 C1-set PF07654.15 PVD19835.1 - 0.018 15.4 3.9 0.72 10.3 0.1 4.2 4 2 0 4 4 4 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 PVD19835.1 - 0.034 14.2 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 PVD19835.1 - 0.14 12.4 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 BTB PF00651.31 PVD19837.1 - 3.6e-16 59.4 0.0 8.8e-16 58.1 0.0 1.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD19837.1 - 0.022 14.9 0.7 0.22 11.7 0.0 2.2 1 1 1 2 2 2 0 BTB And C-terminal Kelch Ig_3 PF13927.6 PVD19838.1 - 1.8e-18 66.9 0.1 7.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19838.1 - 2.7e-18 65.8 0.0 1.1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD19838.1 - 3.5e-13 49.5 0.1 4.2e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19838.1 - 3.9e-12 46.3 0.1 9.5e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19838.1 - 2e-11 44.1 0.0 8.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 PVD19838.1 - 0.0012 19.2 0.1 0.59 10.6 0.0 3.3 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD19838.1 - 0.0053 16.3 0.1 0.75 9.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 PVD19838.1 - 0.012 15.8 0.1 35 4.7 0.0 3.4 3 1 1 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD19838.1 - 0.021 14.9 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 PVD19838.1 - 0.04 14.3 0.0 0.31 11.5 0.0 2.3 2 1 0 2 2 2 0 Immunoglobulin C1-set domain UPF0688 PF15772.5 PVD19839.1 - 0.078 13.2 0.1 0.082 13.2 0.1 1.1 1 0 0 1 1 1 0 UPF0688 family zf-C4_ClpX PF06689.13 PVD19840.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 ClpX C4-type zinc finger ADAM_spacer1 PF05986.14 PVD19841.1 - 2.3e-21 75.9 0.0 3.8e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 PVD19841.1 - 1.3e-10 41.3 76.4 4.7e-05 23.5 6.3 6.9 6 1 1 7 7 7 5 Thrombospondin type 1 domain PLAC PF08686.11 PVD19841.1 - 1.4e-08 35.3 10.0 1.4e-08 35.3 10.0 2.8 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain DUF4215 PF13948.6 PVD19841.1 - 0.0034 17.8 16.2 0.086 13.3 0.1 4.5 3 1 1 4 4 4 2 Domain of unknown function (DUF4215) MazG_C PF18722.1 PVD19842.1 - 0.017 14.6 1.1 0.036 13.6 1.1 1.5 1 0 0 1 1 1 0 MazG C-terminal domain Pox_P4B PF03292.14 PVD19842.1 - 0.07 11.4 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Lipase PF00151.19 PVD19843.1 - 1.6e-94 316.9 0.1 1.9e-94 316.7 0.1 1.0 1 0 0 1 1 1 1 Lipase Hydrolase_4 PF12146.8 PVD19843.1 - 7.6e-06 25.4 0.4 1e-05 25.0 0.4 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD19843.1 - 2.1e-05 25.2 0.4 3.1e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD19843.1 - 0.00038 20.2 0.3 0.00073 19.3 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 PVD19843.1 - 0.019 14.5 0.8 0.027 14.0 0.8 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 PVD19843.1 - 0.023 14.5 0.3 0.036 13.9 0.3 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MHC_I_C PF06623.11 PVD19843.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 MHC_I C-terminus ADH_N PF08240.12 PVD19844.1 - 8.2e-28 96.5 0.6 1.8e-27 95.4 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PVD19844.1 - 8e-16 58.2 0.1 1.8e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD19844.1 - 5.5e-07 29.3 0.2 1.3e-06 28.1 0.2 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PVD19844.1 - 5.6e-06 27.4 0.0 9.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PVD19844.1 - 0.019 14.3 0.2 0.03 13.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 PVD19844.1 - 0.099 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PVD19844.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NADH_4Fe-4S PF10589.9 PVD19844.1 - 0.21 11.7 2.0 0.51 10.4 2.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ADH_zinc_N PF00107.26 PVD19845.1 - 3.1e-14 53.1 0.0 1e-13 51.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD19845.1 - 2.5e-10 41.5 0.0 3.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD19845.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 PVD19846.1 - 1.3e-53 179.5 11.4 5.2e-29 100.3 0.2 2.8 3 0 0 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PVD19846.1 - 1.1e-14 54.5 0.0 2.4e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD19846.1 - 0.00061 20.8 0.0 0.0011 20.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.9 PVD19846.1 - 0.033 14.2 8.1 0.11 12.5 0.2 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Glu_dehyd_C PF16912.5 PVD19846.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF2249 PF10006.9 PVD19846.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) ADH_zinc_N PF00107.26 PVD19847.1 - 1.3e-19 70.5 1.0 2.1e-19 69.8 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD19847.1 - 2e-12 47.0 0.9 3.2e-12 46.4 0.9 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PVD19847.1 - 0.00015 22.9 0.1 0.00033 21.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PVD19847.1 - 0.0018 17.6 0.9 0.0018 17.6 0.9 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 PVD19847.1 - 0.016 15.5 1.0 0.026 14.8 1.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_N PF08240.12 PVD19847.1 - 0.064 13.1 3.8 0.043 13.7 1.2 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain 7tm_1 PF00001.21 PVD19848.1 - 5.2e-29 101.4 7.5 7.6e-29 100.8 7.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD19848.1 - 1.2e-08 34.7 7.0 1.7e-08 34.2 7.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD19848.1 - 2.8e-05 24.0 5.1 3.5e-05 23.7 5.1 1.1 1 0 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 PVD19848.1 - 0.14 11.9 6.1 0.21 11.3 6.1 1.3 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 PVD19849.1 - 2.9e-22 79.3 0.7 3.3e-22 79.1 0.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD19849.1 - 0.0032 17.3 0.5 0.23 11.2 0.2 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD19849.1 - 0.013 14.9 0.4 0.021 14.2 0.4 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx MFS_1 PF07690.16 PVD19849.1 - 0.13 11.2 5.2 0.18 10.7 5.2 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily VRR_NUC PF08774.11 PVD19850.1 - 6.7e-19 68.0 0.0 1.7e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Sugar_tr PF00083.24 PVD19851.1 - 2.4e-32 112.4 17.7 3.4e-32 111.9 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD19851.1 - 2.5e-20 72.7 28.6 9.6e-11 41.2 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 PVD19851.1 - 0.78 9.4 0.0 0.78 9.4 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) GTP_EFTU PF00009.27 PVD19852.1 - 6.3e-65 218.4 0.0 9.4e-65 217.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PVD19852.1 - 2.1e-33 114.7 0.0 9.1e-33 112.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 PVD19852.1 - 2.7e-22 78.6 0.0 6.3e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PVD19852.1 - 4.5e-14 52.6 0.1 1.2e-13 51.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PVD19852.1 - 2.4e-13 50.0 0.0 5.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PVD19852.1 - 3.2e-06 27.2 0.1 1.4e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD19852.1 - 0.0083 16.2 0.1 4.2 7.4 0.2 2.6 2 1 0 2 2 2 2 Dynamin family RF3_C PF16658.5 PVD19852.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PAD_M PF08527.10 PVD19852.1 - 0.062 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain PID PF00640.23 PVD19853.1 - 6.3e-42 142.9 1.7 7.1e-42 142.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 PVD19853.1 - 3.7e-25 88.1 0.8 1.4e-11 44.5 0.4 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD19853.1 - 4.2e-15 55.3 0.8 1.6e-06 27.8 0.1 2.7 2 0 0 2 2 2 2 PDZ domain NRho PF16733.5 PVD19853.1 - 0.023 14.8 0.7 0.064 13.3 0.1 2.0 2 0 0 2 2 2 0 Rhomboid N-terminal domain PDZ_2 PF13180.6 PVD19853.1 - 0.03 14.6 0.1 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 PDZ domain SCAMP PF04144.13 PVD19854.1 - 5.9e-60 202.5 21.1 7.1e-60 202.3 21.1 1.1 1 0 0 1 1 1 1 SCAMP family OmpH PF03938.14 PVD19854.1 - 0.21 11.9 5.5 0.15 12.4 1.8 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Adaptin_N PF01602.20 PVD19855.1 - 1.8e-118 396.4 19.2 9.7e-96 321.4 8.7 3.1 1 1 2 3 3 3 3 Adaptin N terminal region AP3B1_C PF14796.6 PVD19855.1 - 2.5e-39 134.9 1.2 1.1e-38 132.8 1.2 2.1 1 1 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 PVD19855.1 - 1.3e-20 74.1 5.0 2e-19 70.2 0.4 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD19855.1 - 9.5e-09 35.5 5.4 8.8e-06 26.0 0.2 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 PVD19855.1 - 1.5e-05 24.8 4.2 0.94 9.9 0.0 5.2 5 0 0 5 5 4 2 HEAT repeat SDA1 PF05285.12 PVD19855.1 - 0.00044 19.8 43.8 0.00044 19.8 43.8 2.2 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 PVD19855.1 - 0.00096 17.5 35.7 0.00096 17.5 35.7 1.8 2 0 0 2 2 2 1 Nop14-like family HEAT_EZ PF13513.6 PVD19855.1 - 0.0029 18.1 0.4 4.3 8.0 0.1 3.5 2 1 1 3 3 3 1 HEAT-like repeat BUD22 PF09073.10 PVD19855.1 - 1 8.6 59.4 0.14 11.5 53.7 2.0 2 0 0 2 2 2 0 BUD22 Mpp10 PF04006.12 PVD19855.1 - 1.2 7.5 42.1 0.18 10.2 35.1 2.1 2 0 0 2 2 2 0 Mpp10 protein SAPS PF04499.15 PVD19855.1 - 3.6 6.3 17.7 7.9 5.1 17.7 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 PVD19855.1 - 4.4 6.0 22.0 0.048 12.4 14.1 1.7 2 0 0 2 2 2 0 Presenilin zf-C3HC4_2 PF13923.6 PVD19856.1 - 7.1e-07 29.0 8.6 7.1e-07 29.0 8.6 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD19856.1 - 1.1e-06 28.4 8.4 1.1e-06 28.4 8.4 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD19856.1 - 5.8e-06 26.6 9.9 5.8e-06 26.6 9.9 3.4 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 PVD19856.1 - 3.7e-05 23.9 8.4 3.7e-05 23.9 8.4 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD19856.1 - 0.00012 22.0 1.9 0.00012 22.0 1.9 3.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD19856.1 - 0.00014 21.6 5.8 0.00014 21.6 5.8 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD19856.1 - 0.00065 19.6 6.9 0.00065 19.6 6.9 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD19856.1 - 0.0025 17.9 6.8 0.0025 17.9 6.8 3.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING FAST_1 PF06743.15 PVD19858.1 - 0.00014 21.7 0.2 0.53 10.3 0.2 2.6 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 PVD19858.1 - 0.0031 17.6 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.12 PVD19859.1 - 1.9e-07 31.8 0.7 1.4e-06 28.9 0.1 2.8 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 PVD19859.1 - 2.8e-07 30.4 0.3 2.8e-07 30.4 0.3 4.3 3 2 3 6 6 6 1 FAST kinase-like protein, subdomain 1 Coatomer_E PF04733.14 PVD19860.1 - 3.8e-117 390.8 4.6 4.3e-117 390.7 4.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 PVD19860.1 - 4.1e-12 46.4 5.7 7.3e-06 26.4 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD19860.1 - 9.4e-09 35.4 3.2 0.0086 16.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19860.1 - 6.1e-08 32.2 5.5 0.00017 21.5 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD19860.1 - 1.7e-07 31.4 4.7 0.0017 18.5 0.2 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PVD19860.1 - 3.8e-07 30.3 2.1 0.00022 21.5 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19860.1 - 1.4e-06 27.9 4.0 0.0005 19.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD19860.1 - 5.7e-05 23.7 10.0 9.2e-05 23.0 0.2 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD19860.1 - 0.00031 20.6 1.0 0.036 14.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD19860.1 - 0.0012 18.5 0.2 0.091 12.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat SRP_TPR_like PF17004.5 PVD19860.1 - 0.013 15.5 3.0 0.75 9.8 0.4 3.0 1 1 1 3 3 3 0 Putative TPR-like repeat TPR_8 PF13181.6 PVD19860.1 - 0.032 14.5 4.0 3.6 8.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD19860.1 - 0.032 13.6 0.7 0.39 10.0 0.0 2.3 1 1 2 3 3 3 0 MalT-like TPR region TPR_21 PF09976.9 PVD19860.1 - 0.045 13.5 2.0 3.3 7.4 0.5 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 PVD19860.1 - 0.052 14.2 2.1 1.7 9.5 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat HemY_N PF07219.13 PVD19860.1 - 0.054 13.7 0.6 15 5.9 0.0 3.0 2 1 1 3 3 3 0 HemY protein N-terminus FAT PF02259.23 PVD19860.1 - 0.078 12.2 2.0 0.21 10.7 1.6 1.7 1 1 1 2 2 2 0 FAT domain TPR_10 PF13374.6 PVD19860.1 - 0.16 11.8 2.2 1.7 8.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19860.1 - 0.17 12.6 10.7 19 6.2 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Com_YlbF PF06133.11 PVD19860.1 - 0.22 12.2 0.1 0.22 12.2 0.1 3.0 3 1 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CTC1 PF15489.6 PVD19861.1 - 7.8e-19 66.8 5.8 1.7e-10 39.2 0.0 4.9 2 1 2 4 4 4 4 CST, telomere maintenance, complex subunit CTC1 Forkhead PF00250.18 PVD19862.1 - 3.3e-20 72.1 0.0 6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Pep_M12B_propep PF01562.19 PVD19866.1 - 4.9e-30 104.6 0.6 1.3e-29 103.2 0.2 1.9 2 1 0 2 2 2 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 PVD19867.1 - 4.1e-20 71.9 0.0 6.9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 PVD19867.1 - 6.8e-20 71.4 6.5 6.8e-20 71.4 6.5 6.3 5 2 2 8 8 8 2 ADAM cysteine-rich domain Reprolysin PF01421.19 PVD19867.1 - 2.7e-16 60.1 0.2 5.6e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 PVD19867.1 - 1.5e-11 44.3 29.7 3.7e-09 36.7 8.0 7.7 7 1 0 7 7 7 3 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 PVD19867.1 - 6.9e-10 39.5 0.2 1.9e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD19867.1 - 3.2e-08 34.0 2.6 1e-07 32.3 2.6 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD19867.1 - 3.8e-06 26.9 0.1 8.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD19867.1 - 0.0006 19.5 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 PVD19867.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A TSP_1 PF00090.19 PVD19868.1 - 5.1e-09 36.2 25.6 5.1e-06 26.6 11.8 4.6 5 1 0 5 5 5 2 Thrombospondin type 1 domain PLAC PF08686.11 PVD19868.1 - 0.00016 22.4 7.2 0.00056 20.6 7.2 2.0 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Lectin_C PF00059.21 PVD19869.1 - 1.1e-11 45.3 1.5 1.1e-11 45.3 1.5 1.7 2 0 0 2 2 2 1 Lectin C-type domain MID_MedPIWI PF18296.1 PVD19869.1 - 0.11 12.3 2.9 0.16 11.7 2.9 1.2 1 0 0 1 1 1 0 MID domain of medPIWI SOG2 PF10428.9 PVD19869.1 - 0.58 9.3 10.7 0.77 8.9 10.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein An_peroxidase PF03098.15 PVD19871.1 - 3e-140 468.3 0.0 5.8e-140 467.4 0.0 1.4 2 0 0 2 2 2 1 Animal haem peroxidase NAD_binding_6 PF08030.12 PVD19871.1 - 2.6e-17 63.4 0.0 5.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PVD19871.1 - 4.4e-14 52.5 0.0 1.5e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain EF-hand_7 PF13499.6 PVD19871.1 - 6.4e-10 39.3 5.6 6.3e-06 26.5 1.6 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD19871.1 - 2e-08 33.2 7.7 4.1e-05 22.8 0.8 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PVD19871.1 - 1.1e-07 31.5 3.2 6.9e-05 22.6 0.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD19871.1 - 8e-07 28.5 3.8 0.015 15.2 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PVD19871.1 - 0.0008 18.8 0.8 0.076 12.5 0.2 2.7 2 0 0 2 2 2 1 EF hand Ferric_reduct PF01794.19 PVD19871.1 - 0.0015 18.6 4.6 0.004 17.3 4.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component RST PF12174.8 PVD19871.1 - 0.0018 18.1 0.2 0.005 16.7 0.2 1.7 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain NAD_binding_1 PF00175.21 PVD19871.1 - 0.023 15.4 0.0 0.056 14.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Adipogenin PF15202.6 PVD19871.1 - 0.22 11.6 0.5 0.67 10.0 0.5 1.8 1 0 0 1 1 1 0 Adipogenin DUF3169 PF11368.8 PVD19872.1 - 0.00024 20.7 0.5 0.00026 20.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Na_Ca_ex PF01699.24 PVD19872.1 - 0.0021 18.0 0.0 0.0023 17.9 0.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4191 PF13829.6 PVD19872.1 - 0.0021 17.4 0.9 0.0025 17.2 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) GWT1 PF06423.12 PVD19872.1 - 0.0028 17.8 0.6 0.0032 17.6 0.6 1.1 1 0 0 1 1 1 1 GWT1 ArsP_2 PF11449.8 PVD19872.1 - 0.0036 16.6 0.4 0.004 16.4 0.4 1.0 1 0 0 1 1 1 1 Putative, 10TM heavy-metal exporter Orf78 PF06024.12 PVD19872.1 - 0.0042 17.4 0.9 0.0042 17.4 0.9 1.9 1 1 1 2 2 2 1 Orf78 (ac78) DUF979 PF06166.12 PVD19872.1 - 0.0062 15.7 0.5 0.007 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF979) SARAF PF06682.12 PVD19872.1 - 0.0063 16.2 1.8 0.0093 15.7 1.8 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3040 PF11239.8 PVD19872.1 - 0.0068 16.7 0.0 0.0082 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) DUF5345 PF17280.2 PVD19872.1 - 0.0082 16.1 7.7 0.0091 15.9 6.9 1.6 1 1 1 2 2 2 1 Family of unknown function (DUF5345) OPT PF03169.15 PVD19872.1 - 0.01 14.5 0.2 0.012 14.3 0.2 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein CD34_antigen PF06365.12 PVD19872.1 - 0.011 15.3 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2722 PF10846.8 PVD19872.1 - 0.012 14.6 6.1 0.012 14.6 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Gaa1 PF04114.14 PVD19872.1 - 0.017 14.2 0.4 0.018 14.1 0.4 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DcuA_DcuB PF03605.14 PVD19872.1 - 0.018 14.0 1.2 0.023 13.6 1.2 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Paf67 PF10255.9 PVD19872.1 - 0.018 14.1 3.1 0.018 14.1 3.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 E1-E2_ATPase PF00122.20 PVD19872.1 - 0.018 14.5 0.7 0.023 14.2 0.7 1.2 1 0 0 1 1 1 0 E1-E2 ATPase MerC PF03203.14 PVD19872.1 - 0.033 14.6 0.0 0.041 14.3 0.0 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF846 PF05832.12 PVD19872.1 - 0.035 14.1 1.1 0.044 13.8 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Med15 PF09606.10 PVD19872.1 - 0.037 12.7 7.5 0.035 12.8 7.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PEX11 PF05648.14 PVD19872.1 - 0.042 13.3 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2207 PF09972.9 PVD19872.1 - 0.045 12.5 1.2 0.069 11.9 1.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5383 PF17355.2 PVD19872.1 - 0.045 14.1 0.6 0.045 14.1 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Mak10 PF04112.13 PVD19872.1 - 0.067 12.7 0.5 0.077 12.5 0.5 1.1 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NapE PF06796.11 PVD19872.1 - 0.07 12.7 0.4 0.07 12.7 0.4 2.3 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE FA_desaturase PF00487.24 PVD19872.1 - 0.08 12.8 0.0 0.08 12.8 0.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase TMEM171 PF15471.6 PVD19872.1 - 0.082 11.9 2.9 0.094 11.7 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF533 PF04391.12 PVD19872.1 - 0.095 12.3 5.5 0.12 12.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) T2SSF PF00482.23 PVD19872.1 - 0.13 12.2 2.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F CrgA PF06781.12 PVD19872.1 - 0.17 12.0 1.2 0.28 11.3 1.2 1.5 1 1 0 1 1 1 0 Cell division protein CrgA Spo7 PF03907.13 PVD19872.1 - 0.17 11.3 1.8 0.21 11.0 1.8 1.2 1 0 0 1 1 1 0 Spo7-like protein OAD_gamma PF04277.13 PVD19872.1 - 0.25 12.0 0.0 0.25 12.0 0.0 1.9 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain 7tm_1 PF00001.21 PVD19872.1 - 0.38 10.0 3.7 0.71 9.1 3.7 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CCSMST1 PF15013.6 PVD19872.1 - 0.5 10.6 5.3 0.12 12.6 1.6 1.8 1 1 1 2 2 2 0 CCSMST1 family DUF2157 PF09925.9 PVD19872.1 - 0.59 9.9 5.0 1.9 8.2 5.0 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) 7TM_GPCR_Srv PF10323.9 PVD19872.1 - 1.2 8.5 11.8 2.9 7.2 11.8 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2615 PF11027.8 PVD19872.1 - 1.5 9.0 10.2 0.1 12.7 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) YrhC PF14143.6 PVD19872.1 - 1.5 8.9 6.0 0.68 10.1 0.2 2.3 1 1 1 2 2 2 0 YrhC-like protein CYSTM PF12734.7 PVD19872.1 - 1.9 8.9 11.0 3 8.2 11.0 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Spt20 PF12090.8 PVD19872.1 - 1.9 8.1 17.4 2.2 7.8 17.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4064 PF13273.6 PVD19872.1 - 2.1 8.6 7.5 22 5.4 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) ODV-E18 PF10717.9 PVD19872.1 - 2.2 8.2 4.2 7.8 6.5 0.2 2.1 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 PrgI PF12666.7 PVD19872.1 - 2.5 8.9 9.1 0.25 12.1 4.7 1.5 2 0 0 2 2 1 0 PrgI family protein Med3 PF11593.8 PVD19872.1 - 3.7 6.7 13.4 4 6.5 13.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4131 PF13567.6 PVD19872.1 - 5.1 6.7 8.8 0.52 9.9 4.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Chordopox_A13L PF05961.11 PVD19872.1 - 7.2 6.9 13.7 0.19 12.0 1.0 2.3 1 1 1 2 2 2 0 Chordopoxvirus A13L protein MazG_C PF18722.1 PVD19873.1 - 0.032 13.7 1.3 0.081 12.4 1.3 1.6 1 0 0 1 1 1 0 MazG C-terminal domain Pox_P4B PF03292.14 PVD19873.1 - 0.051 11.9 0.0 0.086 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Mpp10 PF04006.12 PVD19874.1 - 1.4e-166 555.6 73.4 1.9e-166 555.2 73.4 1.2 1 0 0 1 1 1 1 Mpp10 protein Med11 PF10280.9 PVD19874.1 - 0.0052 17.3 1.1 0.0052 17.3 1.1 3.5 3 1 0 3 3 3 1 Mediator complex protein HET-s_218-289 PF11558.8 PVD19874.1 - 0.061 13.4 0.2 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Het-s 218-289 Yip1 PF04893.17 PVD19875.1 - 0.012 15.4 1.4 0.012 15.4 1.4 1.6 2 0 0 2 2 2 0 Yip1 domain 7tm_1 PF00001.21 PVD19875.1 - 1.6 8.0 5.2 8.8 5.6 5.1 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PI3_PI4_kinase PF00454.27 PVD19877.1 - 1.3e-54 185.7 0.2 6.5e-54 183.4 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PVD19877.1 - 2.6e-42 145.3 4.0 2.6e-42 145.3 4.0 4.2 4 1 1 5 5 4 1 FAT domain DUF4659 PF15558.6 PVD19877.1 - 1.1e-22 80.5 77.1 1.1e-22 80.5 77.1 3.0 4 0 0 4 4 2 1 Domain of unknown function (DUF4659) FATC PF02260.20 PVD19877.1 - 1.6e-15 56.6 0.1 6.7e-15 54.6 0.0 2.2 2 0 0 2 2 2 1 FATC domain UME PF08064.13 PVD19877.1 - 3.5e-14 52.5 1.2 2.8e-13 49.6 0.4 3.2 2 0 0 2 2 2 1 UME (NUC010) domain TPR_14 PF13428.6 PVD19877.1 - 0.00014 22.4 1.2 0.58 11.1 0.1 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19877.1 - 0.0052 16.8 4.3 0.046 13.8 0.2 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD19877.1 - 0.006 17.1 0.0 0.044 14.3 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19877.1 - 0.0088 16.2 1.2 0.21 11.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19877.1 - 0.017 14.9 0.1 0.017 14.9 0.1 3.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD19877.1 - 0.02 14.9 0.4 1.4 9.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HSCB_C PF07743.13 PVD19878.1 - 5.7e-16 58.8 2.8 6.6e-16 58.6 0.1 2.2 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 PVD19878.1 - 3.5e-05 23.9 0.6 3.5e-05 23.9 0.6 2.0 3 0 0 3 3 3 1 DnaJ domain HscB_4_cys PF18256.1 PVD19878.1 - 0.0017 18.1 3.3 0.03 14.1 3.5 2.2 1 1 1 2 2 2 1 Co-chaperone HscB tetracysteine metal binding motif OmpH PF03938.14 PVD19878.1 - 0.026 14.9 2.7 0.32 11.3 0.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4745 PF15923.5 PVD19878.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) FlxA PF14282.6 PVD19878.1 - 0.3 11.1 4.4 1.5 8.8 1.8 2.2 2 0 0 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 PVD19878.1 - 0.33 11.2 6.1 1.4 9.2 1.4 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain FIST_C PF10442.9 PVD19879.1 - 1.2e-09 38.2 0.1 3.3e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 FIST C domain F-box PF00646.33 PVD19879.1 - 0.003 17.4 0.1 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PVD19879.1 - 0.0042 16.9 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF2369 PF10179.9 PVD19879.1 - 0.14 12.5 0.1 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Spaetzle PF16077.5 PVD19880.1 - 0.00018 22.0 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 Spaetzle Spaetzle PF16077.5 PVD19881.1 - 0.016 15.7 0.5 0.036 14.6 0.5 1.6 1 0 0 1 1 1 0 Spaetzle Arrestin_C PF02752.22 PVD19882.1 - 1.9e-15 57.5 0.0 3.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD19882.1 - 4.3e-15 56.0 0.0 1.3e-13 51.2 0.0 2.7 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 PVD19882.1 - 0.004 16.4 0.0 0.34 10.0 0.0 2.1 1 1 0 2 2 2 2 Rgp1 DctQ PF04290.12 PVD19884.1 - 0.0065 16.4 6.2 0.0065 16.4 6.2 2.0 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Kinesin PF00225.23 PVD19886.1 - 1.9e-105 352.5 1.7 1.9e-105 352.5 1.7 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD19886.1 - 2.4e-44 150.9 0.3 2.4e-44 150.9 0.3 2.9 2 0 0 2 2 2 1 Microtubule binding Rootletin PF15035.6 PVD19886.1 - 0.00073 19.6 12.0 0.00073 19.6 12.0 7.8 3 2 3 6 6 6 1 Ciliary rootlet component, centrosome cohesion ALP_N PF17989.1 PVD19886.1 - 0.18 12.0 1.2 1.4 9.1 1.2 2.6 1 1 0 1 1 1 0 Actin like proteins N terminal domain Ccdc124 PF06244.12 PVD19887.1 - 9.8e-40 136.1 11.4 9.8e-40 136.1 11.4 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 PVD19887.1 - 2.7e-05 24.5 1.7 2.7e-05 24.5 1.7 3.0 2 1 0 3 3 3 1 HMG (high mobility group) box YABBY PF04690.13 PVD19887.1 - 0.0068 17.0 16.3 0.16 12.5 16.3 2.2 1 1 0 1 1 1 1 YABBY protein L51_S25_CI-B8 PF05047.16 PVD19887.1 - 0.064 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA_18 PF13238.6 PVD19888.1 - 0.00076 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 PVD19888.1 - 0.19 11.5 0.0 3.7 7.2 0.0 2.1 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family Glyco_hydro_30 PF02055.16 PVD19891.1 - 7e-191 633.7 7.5 4.2e-78 262.8 0.1 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 PVD19891.1 - 5.4e-11 42.5 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 PVD19891.1 - 5e-08 32.5 0.1 0.0093 15.2 0.0 3.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 59 TMEM141 PF15110.6 PVD19891.1 - 0.02 15.5 0.1 6.1 7.5 0.0 2.9 3 0 0 3 3 3 0 TMEM141 protein family ATG_C PF09333.11 PVD19892.1 - 0.0003 21.1 0.1 7.3 7.0 0.0 4.3 1 1 2 3 3 3 2 Autophagy-related protein C terminal domain Radial_spoke PF04712.12 PVD19892.1 - 0.018 14.0 0.7 0.025 13.5 0.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Antimicrobial13 PF08108.11 PVD19892.1 - 0.74 10.0 5.4 1.9e+02 2.4 0.1 4.9 4 0 0 4 4 4 0 Halocidin family NICE-3 PF07406.11 PVD19893.1 - 4.5e-52 176.7 0.2 6.4e-52 176.2 0.2 1.2 1 0 0 1 1 1 1 NICE-3 protein ATG16 PF08614.11 PVD19894.1 - 9.1 6.4 139.4 3.3 7.9 19.1 7.5 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) AAA PF00004.29 PVD19895.1 - 5.8e-33 114.1 0.0 1.2e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD19895.1 - 1.1e-10 41.1 0.3 3.7e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain LRR_8 PF13855.6 PVD19895.1 - 7.7e-07 28.8 13.5 2.2e-06 27.3 4.4 3.4 3 1 1 4 4 4 2 Leucine rich repeat RuvB_N PF05496.12 PVD19895.1 - 1.6e-05 24.7 0.0 6.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PVD19895.1 - 0.00045 19.5 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 PVD19895.1 - 0.0005 20.5 0.0 0.0021 18.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PVD19895.1 - 0.00054 20.0 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PVD19895.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain LisH PF08513.11 PVD19895.1 - 0.0016 18.3 0.3 0.0041 17.0 0.3 1.8 1 0 0 1 1 1 1 LisH LRR_4 PF12799.7 PVD19895.1 - 0.0043 17.4 12.7 0.0052 17.2 2.3 3.7 3 1 1 4 4 3 2 Leucine Rich repeats (2 copies) AAA_7 PF12775.7 PVD19895.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PVD19895.1 - 0.0073 16.7 0.0 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 PVD19895.1 - 0.01 16.1 0.1 0.035 14.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD19895.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PVD19895.1 - 0.015 15.8 0.0 0.044 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PVD19895.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 PVD19895.1 - 0.021 14.0 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 PVD19895.1 - 0.032 13.8 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PVD19895.1 - 0.04 13.9 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PVD19895.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 PVD19895.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 PVD19895.1 - 0.1 12.9 0.1 0.24 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD19895.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 PVD19895.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LRR_1 PF00560.33 PVD19895.1 - 0.64 10.8 8.3 7.7 7.5 0.1 3.5 4 0 0 4 4 2 0 Leucine Rich Repeat Glyco_hydro_18 PF00704.28 PVD19896.1 - 9.3e-13 48.6 0.4 1.2e-12 48.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TraQ PF09679.10 PVD19896.1 - 0.055 13.4 0.9 0.15 12.0 0.9 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Glyco_hydro_18 PF00704.28 PVD19897.1 - 4.1e-110 368.4 0.1 3.7e-50 171.4 0.0 4.4 4 1 0 4 4 4 3 Glycosyl hydrolases family 18 DUF4849 PF16141.5 PVD19897.1 - 0.12 11.7 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 Ank_2 PF12796.7 PVD19899.1 - 6.2e-28 97.2 3.9 7.7e-13 48.8 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD19899.1 - 4.9e-25 87.6 2.5 2.2e-08 34.5 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD19899.1 - 2.1e-16 59.7 6.3 1.2e-06 28.6 0.0 5.5 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD19899.1 - 3.7e-15 55.6 11.1 2.4e-05 24.6 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PVD19899.1 - 1.6e-14 52.5 13.3 0.00034 20.8 0.0 7.4 8 1 2 10 10 10 4 Ankyrin repeat SOCS_box PF07525.16 PVD19899.1 - 7.8e-10 38.9 3.1 1.9e-09 37.7 3.1 1.7 1 0 0 1 1 1 1 SOCS box RNase_T PF00929.24 PVD19900.1 - 9.3e-34 117.4 0.1 1.1e-33 117.2 0.1 1.0 1 0 0 1 1 1 1 Exonuclease START PF01852.19 PVD19901.1 - 1.3e-19 70.5 1.4 1.3e-19 70.5 0.1 1.6 2 0 0 2 2 2 1 START domain PH PF00169.29 PVD19901.1 - 2.8e-12 47.1 0.9 5.8e-12 46.1 0.2 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 PVD19901.1 - 5.9e-08 32.9 0.8 1.2e-07 31.9 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PVD19901.1 - 1.9e-06 28.2 0.8 8.3e-05 23.0 0.8 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 PVD19901.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_S30AE PF02482.19 PVD19901.1 - 0.15 12.9 2.0 0.59 11.0 2.0 2.1 1 1 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein F5_F8_type_C PF00754.25 PVD19902.1 - 6.6e-08 32.7 0.0 0.051 13.7 0.0 3.3 3 0 0 3 3 3 3 F5/8 type C domain HalX PF08663.10 PVD19903.1 - 0.0078 16.5 1.6 0.011 16.0 1.6 1.2 1 0 0 1 1 1 1 HalX domain CLZ PF16526.5 PVD19903.1 - 0.16 12.3 4.1 1.8 9.0 0.5 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FWWh PF14922.6 PVD19905.1 - 2.9e-45 153.8 5.8 5.4e-45 152.9 5.8 1.5 1 0 0 1 1 1 1 Protein of unknown function SEO_N PF14576.6 PVD19905.1 - 0.067 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Sieve element occlusion N-terminus Kinesin PF00225.23 PVD19906.1 - 1.2e-95 320.3 0.2 1.9e-95 319.6 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD19906.1 - 2.2e-19 69.9 0.0 5e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ADAM_spacer1 PF05986.14 PVD19907.1 - 5.7e-21 74.7 0.0 1.3e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 PVD19907.1 - 4.1e-16 58.9 120.6 1.3e-06 28.5 7.8 10.1 10 1 0 10 10 10 5 Thrombospondin type 1 domain PLAC PF08686.11 PVD19907.1 - 5.2e-10 39.9 9.8 1.7e-09 38.3 9.8 2.0 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain HA2 PF04408.23 PVD19908.1 - 0.1 12.9 0.0 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 Helicase associated domain (HA2) PRCC PF10253.9 PVD19909.1 - 8.8e-25 88.8 16.2 8.8e-25 88.8 16.2 3.7 2 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting MFS_2 PF13347.6 PVD19910.1 - 8.6e-23 80.6 13.3 9.1e-11 41.0 9.8 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1 PF07690.16 PVD19910.1 - 9.2e-09 34.7 23.1 1.6e-08 33.8 10.9 3.0 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF3703 PF12487.8 PVD19911.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) Ank_4 PF13637.6 PVD19912.1 - 1.8e-15 57.1 0.3 2.6e-08 34.3 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) NUDIX PF00293.28 PVD19912.1 - 3.9e-14 52.8 0.0 7.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 PVD19912.1 - 4.7e-13 49.5 0.2 1.4e-11 44.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD19912.1 - 8.7e-13 48.2 0.0 1.1e-11 44.7 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 PVD19912.1 - 1.8e-08 33.9 2.1 3.8e-08 32.8 2.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_3 PF13606.6 PVD19912.1 - 5.4e-08 32.5 0.0 3.3e-06 27.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PVD19912.1 - 3.4e-07 30.4 0.0 0.00047 20.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat NUDIX-like PF09296.11 PVD19912.1 - 3.6e-05 24.3 0.0 7.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain DNA_ligase_ZBD PF03119.16 PVD19912.1 - 0.1 12.7 2.0 0.29 11.2 2.0 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain C1_1 PF00130.22 PVD19912.1 - 0.1 12.5 0.4 0.29 11.1 0.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PPTA PF01239.22 PVD19913.1 - 1.7e-21 75.2 11.0 4.6e-07 29.3 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PDCD7 PF16021.5 PVD19915.1 - 8.1e-15 54.7 17.9 8.1e-15 54.7 17.9 1.5 2 0 0 2 2 2 1 Programmed cell death protein 7 PDCD7 PF16021.5 PVD19916.1 - 1.1e-43 149.5 1.8 1.3e-43 149.3 1.8 1.0 1 0 0 1 1 1 1 Programmed cell death protein 7 NPR1_interact PF15699.5 PVD19916.1 - 0.015 15.9 5.0 0.023 15.3 5.0 1.2 1 0 0 1 1 1 0 NPR1 interacting Sec16 PF12932.7 PVD19916.1 - 0.13 12.9 0.6 0.19 12.3 0.6 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF2681 PF10883.8 PVD19916.1 - 0.85 10.1 5.3 1.7 9.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) WRNPLPNID PF15017.6 PVD19916.1 - 8.1 7.4 8.6 21 6.1 8.6 1.7 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Vps5 PF09325.10 PVD19917.1 - 2.3e-77 259.7 18.3 4e-77 258.9 18.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 PVD19917.1 - 2.2e-25 88.8 0.1 9.2e-25 86.8 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 PVD19917.1 - 0.00014 21.4 7.5 0.013 15.0 7.6 2.3 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein HrpB7 PF09486.10 PVD19917.1 - 0.017 15.5 12.8 0.21 12.0 0.6 3.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) RE_BsaWI PF18643.1 PVD19917.1 - 0.078 12.9 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 Spc7 PF08317.11 PVD19917.1 - 0.18 10.7 18.9 3.1 6.6 6.5 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Caps_synth_GfcC PF06251.11 PVD19917.1 - 0.2 11.3 2.4 0.24 11.0 1.6 1.6 1 1 0 1 1 1 0 Capsule biosynthesis GfcC DUF1835 PF08874.10 PVD19917.1 - 0.48 10.6 2.7 0.5 10.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) DUF1664 PF07889.12 PVD19917.1 - 1.7 8.7 9.7 1 9.4 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SPATA24 PF15175.6 PVD19917.1 - 2.4 8.0 12.7 0.13 12.1 5.0 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 GrpE PF01025.19 PVD19917.1 - 2.8 7.6 13.9 0.19 11.4 1.8 2.7 1 1 0 2 2 2 0 GrpE FUSC PF04632.12 PVD19917.1 - 2.9 6.3 6.7 3.9 5.9 5.8 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 PVD19917.1 - 4.4 7.7 8.4 1.3 9.4 1.1 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BAR_3 PF16746.5 PVD19917.1 - 7.4 6.2 16.8 1.9 8.2 11.3 2.5 2 1 0 2 2 2 0 BAR domain of APPL family RasGEF PF00617.19 PVD19918.1 - 1.1e-58 198.4 0.0 2.7e-58 197.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.20 PVD19918.1 - 4.1e-33 115.1 3.0 1.1e-32 113.7 3.0 1.8 1 0 0 1 1 1 1 RhoGEF domain RasGEF_N PF00618.20 PVD19918.1 - 7.3e-23 80.8 0.0 6.4e-15 55.3 0.0 3.0 2 0 0 2 2 2 2 RasGEF N-terminal motif PH PF00169.29 PVD19918.1 - 0.0017 18.8 0.0 0.0072 16.8 0.0 2.1 1 1 0 1 1 1 1 PH domain IQ PF00612.27 PVD19918.1 - 0.054 13.3 2.6 0.13 12.1 2.6 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif TGT_C2 PF14810.6 PVD19918.1 - 0.15 12.2 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase PH PF00169.29 PVD19919.1 - 4.2e-20 72.2 0.2 7.9e-20 71.3 0.1 1.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PVD19919.1 - 0.00079 19.8 3.2 0.0014 19.0 1.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 PVD19919.1 - 0.0078 16.5 0.4 0.043 14.1 0.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 PVD19919.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_13 PF16652.5 PVD19919.1 - 0.074 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain C2 PF00168.30 PVD19923.1 - 7.9e-19 67.9 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 PVD19923.1 - 0.00027 20.5 0.0 0.00036 20.2 0.0 1.4 1 1 0 1 1 1 1 CEP76 C2 domain Lon_C PF05362.13 PVD19924.1 - 3.3e-66 222.8 0.0 6.5e-66 221.8 0.0 1.5 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 PVD19924.1 - 5.5e-09 35.9 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase FeS_assembly_P PF01883.19 PVD19925.1 - 2.9e-09 37.0 0.1 5.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Glyco_hydro_1 PF00232.18 PVD19925.1 - 0.065 11.6 0.0 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 I-set PF07679.16 PVD19926.1 - 6.4e-18 64.6 0.1 3.6e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD19926.1 - 7.6e-18 64.9 0.2 1.9e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD19926.1 - 3.6e-14 52.7 0.4 1.2e-05 25.3 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD19926.1 - 3.7e-14 52.8 0.5 5e-08 33.1 0.1 3.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19926.1 - 4.8e-10 39.6 0.1 0.00022 21.5 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD19926.1 - 1.1e-05 24.9 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 PVD19926.1 - 0.00027 21.2 0.7 0.011 16.1 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Herpes_gp2 PF05955.11 PVD19926.1 - 0.034 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Izumo-Ig PF16706.5 PVD19926.1 - 0.054 13.6 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain 7tm_1 PF00001.21 PVD19929.1 - 2.1e-15 56.8 1.8 1.4e-10 41.0 0.3 2.0 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD19931.1 - 0.069 12.5 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sema PF01403.19 PVD19931.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Sema domain Ank_2 PF12796.7 PVD19932.1 - 1.3e-20 73.7 0.2 3.2e-09 37.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD19932.1 - 1.9e-15 56.7 0.1 4.1e-07 30.2 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD19932.1 - 3.8e-14 51.4 0.6 0.48 11.1 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 PVD19932.1 - 2.3e-13 50.4 2.1 0.00093 19.7 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD19932.1 - 1.8e-10 40.8 0.0 0.6 10.7 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Pkinase PF00069.25 PVD19933.1 - 1.1e-43 149.5 0.3 5.3e-42 144.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD19933.1 - 5.2e-37 127.5 0.2 9.5e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase COR PF16095.5 PVD19933.1 - 3.6e-17 62.8 0.2 1.1e-16 61.2 0.2 1.9 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 PVD19933.1 - 8.3e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD19933.1 - 6.7e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Ras family IIGP PF05049.13 PVD19933.1 - 0.0049 16.0 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 PVD19933.1 - 0.008 16.6 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PVD19933.1 - 0.0091 16.4 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LRR_4 PF12799.7 PVD19933.1 - 0.018 15.5 0.8 0.074 13.5 0.8 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) FTA2 PF13095.6 PVD19933.1 - 0.028 14.1 0.0 7.9 6.0 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rad17 PF03215.15 PVD19933.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Pkinase_fungal PF17667.1 PVD19933.1 - 0.046 12.5 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TniB PF05621.11 PVD19933.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 PVD19933.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Guanylate_kin PF00625.21 PVD19933.1 - 0.16 11.7 0.3 0.51 10.0 0.1 1.9 2 0 0 2 2 2 0 Guanylate kinase Flot PF15975.5 PVD19935.1 - 0.01 16.1 40.3 0.18 12.0 4.2 3.7 2 1 1 3 3 3 3 Flotillin DUF966 PF06136.13 PVD19935.1 - 8.9 5.9 20.2 11 5.6 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Integrase_H2C2 PF17921.1 PVD19936.1 - 1.7e-18 66.4 0.9 2.8e-18 65.7 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD19936.1 - 0.00036 20.7 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger SCAN PF02023.17 PVD19936.1 - 0.0006 19.6 1.2 0.00084 19.1 0.1 1.8 2 0 0 2 2 2 1 SCAN domain ZapB PF06005.12 PVD19938.1 - 0.00018 21.9 0.4 0.017 15.5 0.6 2.2 1 1 0 1 1 1 1 Cell division protein ZapB Gp58 PF07902.11 PVD19938.1 - 0.00041 18.8 2.7 0.00046 18.6 2.7 1.0 1 0 0 1 1 1 1 gp58-like protein DUF4094 PF13334.6 PVD19938.1 - 0.0011 19.3 10.0 0.92 10.0 5.0 3.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4094) SlyX PF04102.12 PVD19938.1 - 0.0013 19.4 4.2 0.0053 17.3 4.2 1.9 1 1 0 1 1 1 1 SlyX ADIP PF11559.8 PVD19938.1 - 0.0015 18.6 0.6 0.002 18.2 0.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 PVD19938.1 - 0.0038 17.6 4.2 0.032 14.6 1.2 2.1 1 1 1 2 2 2 2 Flagella accessory protein C (FlaC) DASH_Spc19 PF08287.11 PVD19938.1 - 0.0054 16.6 8.0 0.2 11.6 4.1 2.3 1 1 1 2 2 2 2 Spc19 DUF5082 PF16888.5 PVD19938.1 - 0.0084 16.4 1.2 0.091 13.0 1.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) TSC22 PF01166.18 PVD19938.1 - 0.012 15.9 0.2 0.26 11.6 0.2 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF4686 PF15742.5 PVD19938.1 - 0.012 14.8 2.4 0.018 14.2 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) COG5 PF10392.9 PVD19938.1 - 0.014 15.6 3.5 0.019 15.1 3.5 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 PVD19938.1 - 0.015 15.3 1.1 0.018 15.0 1.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 PVD19938.1 - 0.022 15.0 0.8 0.027 14.7 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 PVD19938.1 - 0.022 14.8 2.0 0.037 14.1 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Herpes_BLLF1 PF05109.13 PVD19938.1 - 0.023 12.7 9.2 0.025 12.6 9.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) KASH_CCD PF14662.6 PVD19938.1 - 0.025 14.4 0.8 0.031 14.1 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF641 PF04859.12 PVD19938.1 - 0.042 14.2 0.2 0.068 13.5 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAUS-augmin3 PF14932.6 PVD19938.1 - 0.045 13.3 0.4 0.056 13.0 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Syntaxin-6_N PF09177.11 PVD19938.1 - 0.059 13.9 1.3 0.14 12.7 1.3 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SKA1 PF07160.12 PVD19938.1 - 0.065 13.1 1.7 0.082 12.7 1.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3540 PF12059.8 PVD19938.1 - 0.067 13.0 2.5 0.08 12.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) bZIP_1 PF00170.21 PVD19938.1 - 0.098 12.8 0.1 0.5 10.5 0.1 1.8 1 1 0 1 1 1 0 bZIP transcription factor DUF211 PF02680.14 PVD19938.1 - 0.1 12.8 2.5 0.67 10.1 2.0 1.9 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 DUF2703 PF10865.8 PVD19938.1 - 0.11 12.7 2.4 0.19 11.9 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2703) Phage_GP20 PF06810.11 PVD19938.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 CLZ PF16526.5 PVD19938.1 - 0.18 12.2 4.1 1.6 9.2 0.7 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 PVD19938.1 - 0.24 11.9 2.1 0.35 11.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 MIS13 PF08202.11 PVD19938.1 - 0.41 9.9 3.9 0.64 9.3 3.9 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Trimer_CC PF08954.11 PVD19938.1 - 0.54 9.9 5.0 15 5.2 5.0 2.4 1 1 0 1 1 1 0 Trimerisation motif Retinal PF15449.6 PVD19938.1 - 0.56 7.9 6.3 0.63 7.8 6.3 1.0 1 0 0 1 1 1 0 Retinal protein LPP PF04728.13 PVD19938.1 - 0.59 10.6 3.4 7 7.1 1.4 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper GIT_CC PF16559.5 PVD19938.1 - 1.1 9.1 8.7 2.7 7.9 4.4 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Shugoshin_N PF07558.11 PVD19938.1 - 1.2 9.1 5.0 6.4 6.7 0.3 2.9 1 1 2 3 3 3 0 Shugoshin N-terminal coiled-coil region EspF PF04806.12 PVD19939.1 - 0.022 15.1 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 EspF protein repeat Ig_3 PF13927.6 PVD19940.1 - 1.1e-10 41.9 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD19940.1 - 1.1e-08 35.1 0.0 1.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD19940.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 PVD19940.1 - 2.9e-05 24.2 0.0 5.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19940.1 - 9.3e-05 22.7 0.0 0.0024 18.2 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 PVD19940.1 - 0.0019 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 PVD19940.1 - 0.08 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Glyoxalase_4 PF13669.6 PVD19941.1 - 8.7e-20 71.0 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 PVD19941.1 - 1.6e-10 41.3 0.0 1.9e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PVD19941.1 - 0.00083 19.5 0.0 0.001 19.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 PVD19941.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 PVD19941.1 - 0.17 12.7 0.0 0.29 11.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Ints3 PF10189.9 PVD19942.1 - 6.7e-105 349.3 0.2 1.4e-104 348.3 0.2 1.6 1 0 0 1 1 1 1 Integrator complex subunit 3 PXA PF02194.15 PVD19942.1 - 0.031 14.3 1.3 0.59 10.1 0.0 3.1 3 0 0 3 3 3 0 PXA domain WGG PF10273.9 PVD19942.1 - 0.1 13.2 0.1 2.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 TSP_1 PF00090.19 PVD19943.1 - 5e-07 29.8 42.9 5.7e-05 23.3 12.0 4.6 3 1 0 3 3 3 3 Thrombospondin type 1 domain PLAC PF08686.11 PVD19943.1 - 0.0029 18.3 0.5 0.01 16.6 0.5 2.1 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Neur_chan_memb PF02932.16 PVD19944.1 - 3.1e-68 230.4 0.1 4.3e-68 229.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 PVD19947.1 - 6.1e-62 209.8 0.7 7e-61 206.3 0.7 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD19947.1 - 1.2e-49 168.7 0.1 1.6e-49 168.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Claudin_2 PF13903.6 PVD19947.1 - 0.027 14.2 1.0 0.044 13.5 1.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction S_4TM PF18159.1 PVD19947.1 - 0.64 9.3 0.0 0.64 9.3 0.0 2.0 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain Neur_chan_LBD PF02931.23 PVD19948.1 - 9.9e-72 240.9 1.9 1.4e-71 240.4 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19948.1 - 2.1e-65 221.1 0.1 2.8e-65 220.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF776 PF05604.11 PVD19949.1 - 0.053 13.9 0.3 0.078 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF776) Neur_chan_LBD PF02931.23 PVD19950.1 - 2.3e-60 203.7 5.1 1.9e-57 194.2 5.1 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD19950.1 - 2.6e-52 178.3 0.3 3.6e-52 177.8 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Mucin PF01456.17 PVD19951.1 - 8.2 6.4 18.8 0.95 9.4 14.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF916 PF06030.12 PVD19953.1 - 0.5 10.4 3.2 1.9 8.6 3.2 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) MNNL PF07657.13 PVD19954.1 - 2.1e-08 34.1 0.0 3.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 N terminus of Notch ligand TMEM171 PF15471.6 PVD19954.1 - 0.63 9.0 3.4 0.87 8.5 3.4 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-RING_UBOX PF13445.6 PVD19955.1 - 1.8e-07 31.1 2.0 1.8e-07 31.1 2.0 3.2 4 1 0 4 4 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD19955.1 - 2.5e-07 30.8 5.4 2.5e-07 30.8 5.4 2.9 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD19955.1 - 4.6e-06 26.4 4.9 4.6e-06 26.4 4.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD19955.1 - 9.4e-06 25.5 8.0 9.4e-06 25.5 8.0 2.8 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD19955.1 - 2e-05 24.3 6.8 2e-05 24.3 6.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD19955.1 - 2.6e-05 24.5 8.9 2.6e-05 24.5 8.9 2.7 2 1 0 2 2 2 1 Ring finger domain Spc7 PF08317.11 PVD19955.1 - 0.00051 19.0 6.6 0.00051 19.0 6.6 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein Atg14 PF10186.9 PVD19955.1 - 0.0023 17.1 1.0 0.0023 17.1 1.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DDE_Tnp_IS66 PF03050.14 PVD19955.1 - 0.019 14.4 0.2 0.32 10.4 0.0 2.4 2 1 1 3 3 3 0 Transposase IS66 family CCDC154 PF15450.6 PVD19955.1 - 0.043 12.4 8.1 0.063 11.8 8.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Exonuc_VII_L PF02601.15 PVD19955.1 - 0.054 13.1 0.4 0.099 12.2 0.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C3HC4_4 PF15227.6 PVD19955.1 - 0.45 10.7 14.1 0.056 13.6 5.6 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 PVD19955.1 - 1.8 8.8 5.2 27 5.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 PVD19955.1 - 3.6 7.5 7.1 0.13 12.2 0.6 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Sgf11 PF08209.11 PVD19956.1 - 0.076 12.6 5.1 3.3 7.4 0.2 3.5 2 2 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_12 PF18658.1 PVD19956.1 - 0.089 12.4 3.1 7.3 6.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger C2H2-type IMS_C PF11799.8 PVD19957.1 - 2.9e-11 44.1 0.3 8.5e-11 42.6 0.3 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 PVD19957.1 - 4.8e-09 36.4 1.9 2.7e-06 27.4 0.1 2.9 3 0 0 3 3 3 2 impB/mucB/samB family IMS_HHH PF11798.8 PVD19957.1 - 4.7e-06 26.6 0.0 1.7e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif MIB_HERC2 PF06701.13 PVD19958.1 - 4e-23 81.4 22.3 5.6e-15 55.3 7.8 3.2 3 0 0 3 3 3 2 Mib_herc2 VWA_2 PF13519.6 PVD19958.1 - 1.3e-10 41.8 0.0 7.2e-10 39.5 0.0 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD19958.1 - 1.4e-05 25.4 0.1 3.6e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain SlyX PF04102.12 PVD19958.1 - 0.0011 19.5 5.8 0.32 11.7 5.7 3.8 3 0 0 3 3 3 1 SlyX CCDC-167 PF15188.6 PVD19958.1 - 0.055 13.8 8.7 0.026 14.9 3.7 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 PVD19958.1 - 0.068 13.2 11.3 0.33 11.0 3.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 PVD19958.1 - 6 5.8 16.1 3.3 6.7 14.0 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Adaptin_binding PF10199.9 PVD19959.1 - 5.2e-15 56.1 0.2 9.6e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 PVD19959.1 - 0.002 17.7 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 Ras family IQ PF00612.27 PVD19960.1 - 0.00071 19.2 0.4 0.0015 18.1 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4663 PF15668.5 PVD19960.1 - 0.11 11.5 1.6 0.2 10.7 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DUF1319 PF07028.11 PVD19960.1 - 0.14 12.4 1.0 0.61 10.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) MIP PF00230.20 PVD19961.1 - 1.6e-46 158.8 6.5 2e-46 158.5 6.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 PVD19962.1 - 1.8e-11 44.2 0.1 2.2e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 PVD19963.1 - 5.5e-24 85.1 18.0 2.8e-21 76.3 0.9 3.1 3 0 0 3 3 3 3 Major intrinsic protein DUF1269 PF06897.12 PVD19963.1 - 0.15 12.4 0.4 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Ost5 PF05251.12 PVD19963.1 - 1.2 9.5 4.3 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 TPR_12 PF13424.6 PVD19964.1 - 2.2e-28 98.3 26.9 2.5e-09 37.3 0.3 7.3 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 PVD19964.1 - 8.3e-26 88.0 23.7 0.0023 17.9 0.2 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD19964.1 - 4.7e-22 76.8 26.3 0.00018 21.2 0.1 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 PVD19964.1 - 8.7e-15 53.6 27.5 0.52 10.7 0.5 11.0 11 1 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 PVD19964.1 - 1.2e-13 51.4 15.2 0.00041 20.9 0.0 8.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD19964.1 - 5.2e-13 48.0 19.5 0.066 13.3 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 PVD19964.1 - 2.1e-10 40.1 13.0 0.11 12.4 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat MIT PF04212.18 PVD19964.1 - 1.4e-09 37.9 12.2 1.9 8.6 0.1 7.5 7 0 0 7 7 7 3 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 PVD19964.1 - 2.6e-09 37.1 12.5 2.7 9.1 0.0 8.4 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD19964.1 - 5.5e-06 26.7 14.1 1.5 9.6 0.2 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat RPN7 PF10602.9 PVD19964.1 - 0.00013 21.7 4.1 0.086 12.5 0.1 4.8 4 2 1 5 5 5 1 26S proteasome subunit RPN7 TPR_11 PF13414.6 PVD19964.1 - 0.00014 21.5 20.6 1.4 8.7 0.7 7.9 9 1 0 9 9 9 2 TPR repeat TPR_5 PF12688.7 PVD19964.1 - 0.00031 21.0 4.6 4.3 7.6 0.1 5.3 3 2 2 5 5 5 1 Tetratrico peptide repeat ANAPC3 PF12895.7 PVD19964.1 - 0.0011 19.1 21.4 1.6 9.0 0.5 7.0 7 2 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 PVD19964.1 - 0.002 17.6 10.1 0.96 8.8 0.5 4.6 4 1 1 5 5 5 2 MalT-like TPR region TPR_19 PF14559.6 PVD19964.1 - 0.0024 18.3 18.4 10 6.7 0.0 7.7 7 2 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD19964.1 - 3 8.1 9.2 41 4.4 0.2 5.3 6 2 1 7 7 7 0 Tetratricopeptide repeat TERB2 PF15101.6 PVD19965.1 - 9.7e-37 127.0 10.8 1e-31 110.6 1.4 2.5 1 1 0 2 2 2 2 Telomere-associated protein TERB2 BRCT_2 PF16589.5 PVD19965.1 - 0.002 18.5 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RR_TM4-6 PF06459.12 PVD19965.1 - 1.5 8.6 6.0 2.1 8.1 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ski_Sno PF02437.17 PVD19966.1 - 4.5e-39 132.5 0.3 7.2e-39 131.9 0.3 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 PVD19966.1 - 2.8e-31 107.6 6.0 2.8e-31 107.6 6.0 2.3 3 0 0 3 3 3 1 c-SKI Smad4 binding domain DUF1980 PF09323.10 PVD19966.1 - 0.32 10.9 1.0 0.71 9.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) P-mevalo_kinase PF04275.14 PVD19967.1 - 3.9e-46 155.7 0.0 6.1e-46 155.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase AAA_18 PF13238.6 PVD19967.1 - 0.059 13.9 0.1 0.15 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Nbas_N PF15492.6 PVD19968.1 - 2.5e-65 220.6 1.4 4.2e-65 219.9 1.4 1.3 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec39 PF08314.11 PVD19968.1 - 1.9e-29 102.7 3.7 1.5e-14 53.5 0.9 2.6 1 1 0 2 2 2 2 Secretory pathway protein Sec39 GDNF PF02351.16 PVD19969.1 - 8.4e-05 23.5 8.9 8.4e-05 23.5 8.9 2.6 2 1 0 2 2 2 2 GDNF/GAS1 domain MAGE_N PF12440.8 PVD19969.1 - 0.062 14.0 0.4 0.062 14.0 0.4 1.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Hid1 PF12722.7 PVD19970.1 - 0.64 8.1 26.1 0.71 7.9 26.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 PVD19970.1 - 1.1 9.3 17.0 1.4 9.0 17.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EVI2A PF05399.11 PVD19970.1 - 7.8 6.0 15.5 11 5.5 15.5 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Pkinase PF00069.25 PVD19971.1 - 4.8e-52 176.9 0.0 5e-25 88.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD19971.1 - 2.3e-31 109.0 0.1 2.8e-18 66.2 0.1 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase MIT PF04212.18 PVD19971.1 - 4.2e-24 84.4 2.3 6.4e-21 74.2 0.5 3.0 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Effector_1 PF04518.12 PVD19971.1 - 0.1 11.7 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Effector from type III secretion system ABC1 PF03109.16 PVD19971.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family zf-C2HC_2 PF13913.6 PVD19972.1 - 1.2e-80 264.3 44.6 2.9e-12 46.2 0.6 8.3 8 0 0 8 8 8 8 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PVD19972.1 - 2e-11 43.7 23.7 0.13 12.8 0.0 8.3 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD19972.1 - 2.2e-10 40.4 32.3 0.17 12.8 0.1 8.5 8 0 0 8 8 8 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 PVD19972.1 - 6.2e-10 38.8 9.3 1.3 9.0 0.0 6.6 8 0 0 8 8 7 4 Rad50 zinc hook motif zf-RING_7 PF02591.15 PVD19972.1 - 5.3e-09 36.1 3.5 0.48 10.6 0.0 5.3 4 0 0 4 4 4 3 C4-type zinc ribbon domain DUF2318 PF10080.9 PVD19972.1 - 7.9e-09 35.6 17.3 0.5 10.5 0.0 7.8 8 0 0 8 8 8 2 Predicted membrane protein (DUF2318) Sgf11 PF08209.11 PVD19972.1 - 7.1e-07 28.7 27.7 0.017 14.7 0.3 8.1 8 0 0 8 8 8 3 Sgf11 (transcriptional regulation protein) Ribosomal_L32p PF01783.23 PVD19972.1 - 9.8e-07 28.9 7.1 1.3 9.3 0.1 5.0 4 0 0 4 4 4 2 Ribosomal L32p protein family c-SKI_SMAD_bind PF08782.10 PVD19972.1 - 1.7e-06 28.2 15.4 0.12 12.6 0.0 5.7 8 0 0 8 8 6 3 c-SKI Smad4 binding domain zf_UBZ PF18439.1 PVD19972.1 - 0.00025 20.6 12.7 3.8 7.2 0.0 6.9 8 0 0 8 8 8 1 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 PVD19972.1 - 0.00048 20.0 16.4 4.4 7.3 0.1 6.8 7 0 0 7 7 6 1 zinc-ribbon domain ROS_MUCR PF05443.11 PVD19972.1 - 0.0044 17.1 0.0 17 5.5 0.0 4.4 4 1 0 4 4 4 0 ROS/MUCR transcriptional regulator protein zf-CpG_bind_C PF12269.8 PVD19972.1 - 0.066 13.0 6.9 53 3.5 0.0 5.9 8 0 0 8 8 8 0 CpG binding protein zinc finger C terminal domain zf-HC5HC2H PF13771.6 PVD19972.1 - 0.13 12.5 11.1 3.6 7.9 0.0 4.9 6 0 0 6 6 4 0 PHD-like zinc-binding domain DUF2256 PF10013.9 PVD19972.1 - 0.15 12.2 26.8 9.6 6.4 0.1 8.2 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FPG_IleRS PF06827.14 PVD19972.1 - 0.25 11.2 11.1 12 5.9 0.2 4.7 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-H2C2_2 PF13465.6 PVD19972.1 - 0.33 11.5 16.4 37 5.0 0.0 7.0 8 0 0 8 8 7 0 Zinc-finger double domain HNH_5 PF14279.6 PVD19972.1 - 1.3 8.9 18.5 17 5.4 0.1 6.5 8 0 0 8 8 8 0 HNH endonuclease GcpE PF04551.14 PVD19972.1 - 3.9 6.5 6.5 4 6.4 0.2 3.4 4 1 0 4 4 4 0 GcpE protein zf-C2H2_6 PF13912.6 PVD19972.1 - 5.7 7.1 27.2 30 4.8 0.0 7.9 8 0 0 8 8 8 0 C2H2-type zinc finger TBCA PF02970.16 PVD19973.1 - 1.5e-28 99.0 11.1 1.9e-28 98.6 11.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A GIDA_assoc PF13932.6 PVD19973.1 - 0.01 16.0 4.4 0.013 15.7 4.4 1.0 1 0 0 1 1 1 0 GidA associated domain DUF4972 PF16342.5 PVD19973.1 - 0.035 13.8 3.0 0.043 13.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF948 PF06103.11 PVD19973.1 - 0.055 13.7 1.1 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2670 PF10875.8 PVD19973.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) HSP70 PF00012.20 PVD19973.1 - 0.22 9.6 6.8 0.26 9.4 6.8 1.0 1 0 0 1 1 1 0 Hsp70 protein FapA PF03961.13 PVD19973.1 - 0.25 9.9 7.1 0.27 9.8 7.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nup88 PF10168.9 PVD19973.1 - 0.46 8.2 8.5 0.51 8.1 8.5 1.0 1 0 0 1 1 1 0 Nuclear pore component Cep57_CLD_2 PF14197.6 PVD19973.1 - 1.8 8.7 10.9 1.7 8.8 1.5 2.4 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_23 PF13476.6 PVD19973.1 - 3.1 8.2 9.5 3.8 7.9 9.5 1.1 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 PVD19973.1 - 6.1 7.0 12.1 1.8 8.7 1.5 2.8 1 1 2 3 3 3 0 bZIP transcription factor Glycos_transf_2 PF00535.26 PVD19975.1 - 3.2e-08 33.6 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 PVD19976.1 - 5.1e-16 59.0 0.0 8.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD19976.1 - 1.8e-13 50.9 0.4 2.9e-13 50.2 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PVD19976.1 - 0.00045 19.8 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Pro_isomerase PF00160.21 PVD19978.1 - 5.9e-24 85.1 0.1 6.7e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP_assoc PF03828.19 PVD19978.1 - 0.0049 17.1 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Treslin_N PF15292.6 PVD19979.1 - 6.2e-31 107.6 14.0 6.2e-31 107.6 14.0 2.6 2 1 0 2 2 2 2 Treslin N-terminus Pro_isomerase PF00160.21 PVD19979.1 - 6.6e-12 46.0 0.0 2.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Antigen_Bd37 PF11641.8 PVD19979.1 - 0.13 11.8 1.6 0.27 10.7 1.6 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Glyco_transf_21 PF13506.6 PVD19980.1 - 9.3e-41 139.2 0.0 1.4e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 PVD19980.1 - 7.2e-14 52.2 0.0 9.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PVD19980.1 - 0.00014 21.8 1.9 0.00014 21.8 1.9 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF3050 PF11251.8 PVD19980.1 - 0.057 13.0 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) FoP_duplication PF13865.6 PVD19981.1 - 2.1 9.0 8.1 2.4 8.8 8.1 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4325 PF14213.6 PVD19983.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) AAA PF00004.29 PVD19984.1 - 2e-40 138.3 0.0 5.3e-40 136.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PVD19984.1 - 3.2e-20 71.8 0.0 7.8e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PVD19984.1 - 1.9e-11 43.6 1.1 3.5e-11 42.7 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 PVD19984.1 - 8.5e-06 26.2 0.5 0.0012 19.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PVD19984.1 - 7.4e-05 22.8 1.2 0.0003 20.8 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PVD19984.1 - 0.00033 19.9 0.3 0.00087 18.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 PVD19984.1 - 0.00041 20.1 0.0 0.001 18.9 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PVD19984.1 - 0.00099 19.3 0.4 0.0036 17.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PVD19984.1 - 0.0047 17.2 0.4 0.097 12.9 0.1 2.5 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 PVD19984.1 - 0.028 13.8 0.7 0.086 12.2 0.0 2.2 3 0 0 3 3 3 0 KaiC CPT PF07931.12 PVD19984.1 - 0.035 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 PVD19984.1 - 0.046 13.9 0.2 0.12 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD19984.1 - 0.053 13.0 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 PVD19984.1 - 0.053 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 PVD19984.1 - 0.055 13.1 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DUF3713 PF12506.8 PVD19984.1 - 0.083 13.2 0.3 0.52 10.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) AAA_28 PF13521.6 PVD19984.1 - 0.087 13.1 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PVD19984.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 PVD19984.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 PVD19984.1 - 0.12 11.9 1.6 0.4 10.2 0.4 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 PVD19984.1 - 0.19 11.6 0.3 2 8.3 0.1 2.2 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 PVD19984.1 - 0.23 11.2 1.8 0.42 10.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain Ribosomal_S16 PF00886.19 PVD19985.1 - 9.5e-14 51.2 0.0 3.4e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S16 zf-met PF12874.7 PVD19986.1 - 8.4e-05 22.8 15.2 0.0046 17.3 0.7 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PVD19986.1 - 0.00066 20.3 26.4 0.089 13.7 0.6 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD19986.1 - 0.0073 16.7 29.2 0.19 12.3 0.8 5.8 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD19986.1 - 0.24 11.8 16.1 3.1 8.2 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PVD19986.1 - 0.96 10.1 6.3 9.6 6.9 0.4 3.6 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats PKcGMP_CC PF16808.5 PVD19987.1 - 0.0019 18.0 3.4 0.0019 18.0 3.4 4.7 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Uso1_p115_C PF04871.13 PVD19988.1 - 0.77 10.1 14.8 0.077 13.4 8.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region COG2 PF06148.11 PVD19988.1 - 1.9 8.6 8.3 0.28 11.3 2.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 PVD19988.1 - 2.5 7.1 11.7 3.3 6.7 11.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 PVD19988.1 - 3.3 7.2 10.7 4.4 6.8 10.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 PVD19988.1 - 5.3 6.2 5.8 4.9 6.3 5.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF4600 PF15372.6 PVD19988.1 - 5.6 7.4 11.4 0.56 10.6 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CENP-H PF05837.12 PVD19988.1 - 9.8 6.6 14.2 0.75 10.2 6.8 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ig_3 PF13927.6 PVD19990.1 - 2.8e-20 72.7 0.0 1.8e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD19990.1 - 1.4e-16 60.4 0.0 1.1e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD19990.1 - 3.2e-15 56.0 0.0 7.7e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD19990.1 - 3.8e-13 49.6 0.2 8.7e-06 25.9 0.0 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD19990.1 - 4.9e-12 46.0 0.0 6.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 PVD19990.1 - 7.5e-07 29.4 0.1 6.7e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 PVD19990.1 - 0.00027 20.4 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD19990.1 - 0.0059 16.6 0.0 0.92 9.6 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD19990.1 - 0.039 14.1 0.1 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Herpes_gE PF02480.16 PVD19990.1 - 0.067 11.9 0.0 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3418 PF11898.8 PVD19991.1 - 0.024 13.3 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) F-box-like PF12937.7 PVD19995.1 - 4.6e-10 39.2 0.5 4.6e-10 39.2 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD19995.1 - 2.7e-05 23.9 5.6 2.7e-05 23.9 0.5 3.4 3 1 1 4 4 4 1 F-box domain Kelch_6 PF13964.6 PVD19996.1 - 8.3e-29 98.9 5.7 8.1e-07 29.1 0.1 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 PVD19996.1 - 2.2e-28 97.7 1.0 4.8e-06 26.4 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD19996.1 - 1.1e-23 83.0 14.9 3.3e-08 33.4 0.0 7.2 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD19996.1 - 5.4e-23 80.0 7.2 1.9e-05 24.4 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PVD19996.1 - 5.5e-22 77.5 2.0 0.00043 20.5 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD19996.1 - 1.8e-21 75.4 7.5 4.1e-05 23.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif ADAM_spacer1 PF05986.14 PVD19997.1 - 7.1e-05 22.8 0.0 9.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 PVD19998.1 - 2.6e-26 91.6 82.6 6.8e-07 29.4 9.0 6.9 6 0 0 6 6 6 6 Thrombospondin type 1 domain PLAC PF08686.11 PVD19998.1 - 4.1e-08 33.8 11.0 4.1e-08 33.8 11.0 2.8 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain BUD22 PF09073.10 PVD19999.1 - 3.9e-07 29.8 62.4 6.6e-07 29.0 7.6 3.7 2 1 2 4 4 4 3 BUD22 Pkinase_Tyr PF07714.17 PVD20000.1 - 1.8e-86 289.6 0.0 2.3e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD20000.1 - 2.3e-47 161.6 0.0 3.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD20000.1 - 1.4e-25 89.1 0.1 2.8e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD20000.1 - 8.8e-11 41.3 0.0 2.3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD20000.1 - 2.6e-08 33.4 0.0 7.4e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD20000.1 - 3.1e-08 33.3 0.0 8e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 PVD20000.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD20000.1 - 0.03 13.7 0.0 0.084 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like SH2_2 PF14633.6 PVD20000.1 - 0.051 13.0 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 SH2 domain Pkinase_fungal PF17667.1 PVD20000.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PVD20000.1 - 0.15 11.0 0.0 0.34 9.8 0.0 1.6 1 1 1 2 2 2 0 Haspin like kinase domain Pepdidase_M14_N PF18027.1 PVD20001.1 - 4.6e-13 49.5 2.8 7.4e-13 48.8 1.0 2.3 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 PVD20001.1 - 1.3e-10 41.6 0.1 3.2e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase 5-FTHF_cyc-lig PF01812.20 PVD20002.1 - 1e-46 159.2 0.0 1.2e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family zf-B_box PF00643.24 PVD20003.1 - 0.00015 21.9 8.1 0.00015 21.9 8.1 3.7 3 0 0 3 3 3 1 B-box zinc finger DUF1664 PF07889.12 PVD20003.1 - 0.003 17.6 3.2 0.003 17.6 3.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) NHL PF01436.21 PVD20003.1 - 0.031 14.3 3.3 0.48 10.6 0.4 4.0 4 1 1 5 5 5 0 NHL repeat DUF4517 PF15006.6 PVD20003.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) GAS PF13851.6 PVD20003.1 - 0.14 11.4 7.1 0.096 12.0 1.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 PVD20003.1 - 2.5 7.6 5.7 3.8 7.0 5.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit VWA PF00092.28 PVD20005.1 - 6e-91 303.4 11.4 8.2e-42 143.4 0.2 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 PVD20005.1 - 1.4e-30 106.1 0.5 5.1e-14 52.8 0.0 2.9 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD20005.1 - 4.3e-12 46.3 1.7 1.5e-05 25.0 0.0 3.6 4 0 0 4 4 4 2 von Willebrand factor type A domain Copine PF07002.16 PVD20005.1 - 4.8e-05 22.9 0.1 0.044 13.2 0.0 2.4 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 PVD20005.1 - 0.00076 19.6 1.1 0.76 9.8 0.1 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus Sec23_trunk PF04811.15 PVD20005.1 - 0.0012 18.5 1.3 2.1 7.8 0.0 3.5 4 0 0 4 4 4 2 Sec23/Sec24 trunk domain DUF1194 PF06707.11 PVD20005.1 - 0.014 14.6 3.9 1.3 8.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1194) Integrin_beta PF00362.18 PVD20005.1 - 0.068 12.8 0.1 1.9 8.1 0.0 2.9 2 1 0 3 3 3 0 Integrin beta chain VWA domain SIS PF01380.22 PVD20005.1 - 0.13 12.1 0.4 4.4 7.2 0.0 3.0 3 0 0 3 3 3 0 SIS domain Pkinase_Tyr PF07714.17 PVD20006.1 - 2.9e-94 315.2 0.0 6.1e-66 222.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PVD20006.1 - 4.2e-54 183.7 0.5 6.9e-39 133.8 0.3 3.7 2 2 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 PVD20006.1 - 0.014 15.0 0.2 0.04 13.5 0.2 1.7 1 0 0 1 1 1 0 RIO1 family FERM_F1 PF18379.1 PVD20006.1 - 0.041 13.9 0.1 0.17 11.9 0.1 2.0 1 1 0 1 1 1 0 FERM F1 ubiquitin-like domain Kdo PF06293.14 PVD20006.1 - 0.053 12.9 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YmgB PF10798.8 PVD20006.1 - 0.068 13.0 0.2 0.23 11.3 0.2 1.9 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR TSP_1 PF00090.19 PVD20008.1 - 9.1e-35 118.6 119.4 1.2e-08 35.1 5.7 12.8 10 1 1 11 11 11 8 Thrombospondin type 1 domain I-set PF07679.16 PVD20008.1 - 1.1e-09 38.3 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD20008.1 - 6e-09 36.4 0.5 2.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD20008.1 - 0.0004 20.7 0.1 0.0022 18.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain DUF3459 PF11941.8 PVD20009.1 - 0.056 13.8 0.1 0.071 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Myosin_head PF00063.21 PVD20010.1 - 3.7e-136 455.1 0.0 5e-76 256.4 0.0 3.1 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 PVD20010.1 - 0.05 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Chitin_synth_2 PF03142.15 PVD20011.1 - 1.5e-29 103.1 1.8 1.5e-29 103.1 1.8 1.7 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD20011.1 - 7.9e-12 45.5 8.6 2.2e-11 44.0 8.6 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD20011.1 - 5.1e-05 23.3 0.0 7.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PVD20011.1 - 0.098 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PVD20011.1 - 0.11 12.0 0.0 0.62 9.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF4044 PF13253.6 PVD20011.1 - 0.18 11.4 1.5 0.52 9.9 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Mhr1 PF12829.7 PVD20012.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Chitin_synth_2 PF03142.15 PVD20013.1 - 1.1e-27 96.9 0.0 2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD20013.1 - 1.6e-11 44.5 0.1 1.6e-11 44.5 0.1 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD20013.1 - 1.6e-10 41.2 0.4 5.1e-10 39.6 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PVD20013.1 - 2.7e-05 24.1 0.1 8.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PVD20013.1 - 0.00051 19.6 0.0 0.013 15.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 21 HDA2-3 PF11496.8 PVD20013.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Tmemb_161AB PF10268.9 PVD20014.1 - 0.036 12.7 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF3899 PF13038.6 PVD20014.1 - 2.7 8.5 5.0 54 4.4 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) DUF1980 PF09323.10 PVD20015.1 - 0.058 13.3 0.4 0.075 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Terpene_synth_C PF03936.16 PVD20016.1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF2502 PF10697.9 PVD20016.1 - 0.075 13.4 4.8 0.097 13.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Cupin_8 PF13621.6 PVD20017.1 - 1.7e-29 103.3 0.3 3.2e-29 102.4 0.3 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PVD20017.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PVD20017.1 - 0.0091 16.4 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C2H2_4 PF13894.6 PVD20018.1 - 3.1e-14 52.4 105.7 0.0057 17.4 1.5 15.6 15 0 0 15 15 15 9 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20018.1 - 2.8e-10 40.1 109.3 0.01 16.3 0.2 15.1 15 0 0 15 15 15 7 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 PVD20018.1 - 3.5e-08 33.1 3.6 3.5e-08 33.1 3.6 7.6 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-LYAR PF08790.11 PVD20018.1 - 0.073 13.0 3.1 1.8 8.5 0.1 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger A2L_zn_ribbon PF08792.10 PVD20018.1 - 0.078 12.7 0.0 0.078 12.7 0.0 7.8 10 0 0 10 10 10 0 A2L zinc ribbon domain zf-C2H2_jaz PF12171.8 PVD20018.1 - 6.2 7.2 39.8 1.1 9.6 0.1 8.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding FERM_C PF09380.10 PVD20019.1 - 6.4e-22 77.8 0.2 1.3e-21 76.8 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD20019.1 - 3.7e-19 69.3 0.0 2.1e-18 66.9 0.0 2.3 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PVD20019.1 - 1.2e-10 41.2 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain AFP PF02420.15 PVD20019.1 - 0.92 10.1 4.8 2.9 8.5 4.8 1.9 1 0 0 1 1 1 0 Insect antifreeze protein repeat Ribosomal_S19 PF00203.21 PVD20020.1 - 1.2e-31 108.4 0.2 1.7e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 NTPase_I-T PF01931.18 PVD20022.1 - 1.7e-11 44.2 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF5427 PF10310.9 PVD20022.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ank_2 PF12796.7 PVD20023.1 - 5.3e-48 161.5 10.3 7.4e-18 64.9 0.6 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD20023.1 - 7.5e-41 136.8 8.5 4.1e-05 23.8 1.5 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 PVD20023.1 - 1.6e-38 130.6 5.7 3.9e-10 40.0 0.1 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20023.1 - 3.4e-36 119.1 15.1 3.4e-06 27.0 0.0 10.8 10 1 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PVD20023.1 - 1.2e-29 102.0 11.1 0.00015 21.9 0.4 7.9 4 2 4 8 8 8 7 Ankyrin repeats (many copies) TPR_10 PF13374.6 PVD20023.1 - 0.0055 16.5 0.4 0.3 11.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD20023.1 - 0.016 15.5 0.0 0.44 10.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.26 PVD20024.1 - 8.2e-27 94.5 0.1 7.1e-26 91.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 VMA21 PF09446.10 PVD20024.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 VMA21-like domain Pet100 PF09803.9 PVD20024.1 - 0.91 10.1 3.4 79 3.9 0.0 3.4 2 1 0 2 2 2 0 Pet100 TED_complement PF07678.14 PVD20025.1 - 3.7e-56 190.4 0.1 5.3e-56 189.9 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD20025.1 - 3.4e-33 114.9 0.2 1.2e-30 106.7 0.0 3.3 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD20025.1 - 1.7e-20 72.7 0.0 4.2e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG3 PF17791.1 PVD20025.1 - 4.4e-20 71.7 2.0 2.8e-19 69.1 1.1 2.9 3 0 0 3 3 3 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD20025.1 - 2.6e-13 50.2 0.0 2.3e-12 47.2 0.0 2.6 3 0 0 3 3 3 1 MG2 domain A2M_recep PF07677.14 PVD20025.1 - 7.9e-12 45.7 0.0 7.9e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG4 PF17789.1 PVD20025.1 - 4.2e-10 39.6 0.0 2.7e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 Macroglobulin domain MG4 MG1 PF17790.1 PVD20025.1 - 0.012 16.0 0.1 0.07 13.5 0.0 2.4 3 0 0 3 3 3 0 Macroglobulin domain MG1 Focadhesin PF11229.8 PVD20026.1 - 1.6e-82 277.7 0.6 2.5e-44 151.5 1.2 2.4 1 1 1 2 2 2 2 Focadhesin DUF3730 PF12530.8 PVD20026.1 - 2.1e-36 125.6 4.8 2.1e-36 125.6 4.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Arm PF00514.23 PVD20026.1 - 0.012 15.6 0.5 7.2 6.8 0.1 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat 7tm_1 PF00001.21 PVD20029.1 - 5.9e-26 91.4 29.2 7.2e-26 91.1 29.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD20029.1 - 4.4e-18 65.6 27.6 6.4e-18 65.1 27.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD20029.1 - 8e-05 22.4 20.9 8e-05 22.4 20.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1980 PF09323.10 PVD20029.1 - 0.16 11.9 0.9 0.45 10.4 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Cyclin_C PF02984.19 PVD20030.1 - 7.3e-29 100.3 0.3 2.1e-28 98.8 0.3 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 PVD20030.1 - 1.8e-23 82.6 0.2 2.7e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain WD40 PF00400.32 PVD20030.1 - 7.6e-22 77.2 13.8 0.00023 21.9 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD20030.1 - 0.00022 21.5 0.1 4 7.8 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD20030.1 - 0.027 13.1 0.1 0.048 12.3 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PVD20030.1 - 0.08 11.9 0.0 9.9 5.0 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 PVD20030.1 - 0.1 11.3 3.2 0.48 9.1 0.0 2.8 3 1 0 3 3 3 0 Nup133 N terminal like zf-RING_UBOX PF13445.6 PVD20031.1 - 0.00017 21.5 1.7 0.73 9.9 0.2 3.3 2 0 0 2 2 2 2 RING-type zinc-finger PfUIS3 PF11567.8 PVD20031.1 - 0.013 15.8 0.5 4.7 7.6 0.0 2.8 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Defensin_1 PF00323.19 PVD20031.1 - 0.024 15.2 0.2 6.1 7.5 0.0 3.2 2 0 0 2 2 2 0 Mammalian defensin UNC45-central PF11701.8 PVD20031.1 - 0.065 13.2 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central zf-C3HC4_2 PF13923.6 PVD20031.1 - 0.11 12.4 2.9 6.8 6.6 0.3 3.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD20031.1 - 0.17 12.0 4.9 5.2 7.3 0.1 3.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD20031.1 - 0.34 10.8 8.7 1.4 8.8 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Tox-ART-HYD1 PF15633.6 PVD20032.1 - 0.0043 17.7 0.0 0.0059 17.3 0.0 1.3 1 1 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase Glyco_hydro_20 PF00728.22 PVD20033.1 - 6.1e-87 292.3 0.0 1e-86 291.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PVD20033.1 - 8.4e-17 62.1 0.0 1.3e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PVD20033.1 - 2.5e-06 28.3 0.0 4.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_C57 PF03290.13 PVD20033.1 - 0.027 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Glyco_hydro_20 PF00728.22 PVD20034.1 - 3.5e-87 293.1 0.0 6.1e-87 292.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PVD20034.1 - 5.6e-17 62.7 0.0 8.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PVD20034.1 - 1.1e-05 26.2 0.0 2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_C57 PF03290.13 PVD20034.1 - 0.0094 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 Vaccinia virus I7 processing peptidase COX5A PF02284.16 PVD20035.1 - 5.9e-21 74.4 0.0 6.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va RasGEF PF00617.19 PVD20035.1 - 0.013 15.7 0.0 0.014 15.6 0.0 1.0 1 0 0 1 1 1 0 RasGEF domain TPR_1 PF00515.28 PVD20036.1 - 8.5e-14 50.7 3.6 0.0002 21.0 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20036.1 - 1.4e-12 46.7 3.2 0.0032 17.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD20036.1 - 2.1e-09 36.9 0.2 0.00044 19.9 0.1 3.1 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 PVD20036.1 - 5.8e-05 23.0 2.1 3.1 8.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat DrsE_2 PF13686.6 PVD20036.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family TPR_17 PF13431.6 PVD20036.1 - 0.027 14.8 5.0 0.063 13.7 0.6 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD20036.1 - 0.037 14.8 0.0 9.4 7.4 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat MnmE_helical PF12631.7 PVD20037.1 - 1.2e-52 179.1 0.3 1.5e-52 178.8 0.3 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 PVD20037.1 - 2.7e-35 121.2 0.0 1e-34 119.3 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 PVD20037.1 - 2.1e-21 76.1 0.0 5.1e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD20037.1 - 1.2e-09 38.3 0.0 0.0014 18.6 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 PVD20037.1 - 1.2e-09 37.9 0.0 9e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PVD20037.1 - 0.00087 19.4 0.2 0.0022 18.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 PVD20037.1 - 0.011 16.1 0.0 0.057 13.8 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 PVD20037.1 - 0.013 16.0 0.0 0.048 14.2 0.0 1.9 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 PVD20037.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 PVD20037.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 PVD20038.1 - 0.00027 21.1 7.0 0.00027 21.1 7.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 PVD20038.1 - 0.0014 16.7 4.0 0.0025 15.9 4.0 1.5 1 0 0 1 1 1 1 Prominin HMMR_N PF15905.5 PVD20038.1 - 0.003 17.1 18.4 0.003 17.1 18.4 2.5 2 1 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal ZapB PF06005.12 PVD20038.1 - 0.0032 17.9 1.8 0.0032 17.9 1.8 4.8 3 1 1 4 4 4 1 Cell division protein ZapB Cnn_1N PF07989.11 PVD20038.1 - 2 8.6 24.2 1.1 9.5 9.4 4.4 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 PVD20038.1 - 5 6.4 25.2 0.019 14.3 13.6 2.1 2 0 0 2 2 2 0 FAM76 protein LMBR1 PF04791.16 PVD20038.1 - 5.1 5.9 8.7 0.055 12.4 1.3 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein zf-C2H2_4 PF13894.6 PVD20039.1 - 7e-25 85.6 71.2 0.0014 19.3 1.8 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20039.1 - 1.4e-21 75.7 81.4 0.00091 19.6 1.7 9.9 9 1 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD20039.1 - 8.8e-16 57.5 70.2 6.5e-07 29.5 1.5 10.6 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD20039.1 - 2.4e-15 56.4 51.2 0.00023 21.4 1.0 9.3 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD20039.1 - 5.9e-12 45.6 53.4 0.00032 21.0 0.9 9.9 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.6 PVD20039.1 - 0.012 15.5 1.3 0.012 15.5 1.3 5.9 6 1 1 7 7 7 0 zinc-finger of acetyl-transferase ESCO Zn-C2H2_12 PF18112.1 PVD20039.1 - 0.032 14.7 0.4 0.032 14.7 0.4 5.2 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 PVD20039.1 - 0.046 13.5 41.7 0.052 13.3 0.1 7.3 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD20039.1 - 0.091 12.8 0.2 0.091 12.8 0.2 10.2 11 0 0 11 11 11 0 C2H2-type zinc finger zf_Hakai PF18408.1 PVD20039.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.5 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain DUF1922 PF09082.10 PVD20039.1 - 0.23 11.8 7.2 1.5 9.1 7.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1922) zf_UBZ PF18439.1 PVD20039.1 - 0.3 10.7 33.2 9.6 5.9 0.2 9.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 PVD20039.1 - 1.7 9.5 36.8 1.6 9.6 3.5 5.7 2 2 1 5 5 5 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 PVD20039.1 - 8.7 6.2 18.7 5.8 6.8 0.6 5.7 5 0 0 5 5 5 0 zinc-ribbon domain Peptidase_S8 PF00082.22 PVD20040.1 - 9.4e-51 172.8 5.7 9.4e-51 172.8 5.7 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 PVD20040.1 - 2.8e-26 91.4 0.5 5.9e-26 90.3 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 PVD20040.1 - 9.3e-13 48.8 1.3 2.4e-12 47.4 1.3 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain VSP PF03302.13 PVD20040.1 - 0.0023 16.8 14.3 0.097 11.5 14.2 2.4 1 1 0 1 1 1 1 Giardia variant-specific surface protein GF_recep_IV PF14843.6 PVD20040.1 - 0.0028 17.4 16.8 0.035 13.9 12.5 2.6 1 1 1 2 2 2 2 Growth factor receptor domain IV Furin-like_2 PF15913.5 PVD20040.1 - 0.015 15.4 1.0 0.015 15.4 1.0 2.3 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich Tir_receptor_C PF07489.11 PVD20040.1 - 0.57 10.1 5.6 1.2 9.1 5.6 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ank_4 PF13637.6 PVD20041.1 - 9.2e-35 118.6 11.5 1.3e-09 38.4 0.2 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20041.1 - 5.2e-34 116.7 5.1 1.5e-13 51.1 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD20041.1 - 2.8e-28 97.1 6.8 6.1e-07 29.6 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PVD20041.1 - 1.3e-26 89.7 3.2 4.4e-05 23.6 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PVD20041.1 - 7.5e-24 83.5 2.4 2e-11 43.9 0.1 4.3 1 1 2 4 4 4 4 Ankyrin repeats (many copies) TMF_DNA_bd PF12329.8 PVD20041.1 - 0.0019 18.1 14.3 0.0019 18.1 14.3 10.6 6 4 5 11 11 10 4 TATA element modulatory factor 1 DNA binding THOC7 PF05615.13 PVD20041.1 - 0.0068 16.7 3.7 0.0068 16.7 3.7 8.2 4 2 3 8 8 6 1 Tho complex subunit 7 Ribosomal_L19 PF01245.20 PVD20041.1 - 0.05 13.5 0.2 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L19 DUF2209 PF09974.9 PVD20041.1 - 1.7 9.0 5.8 5.1 7.5 0.7 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) DUF2353 PF09789.9 PVD20041.1 - 1.9 7.8 86.9 0.084 12.2 19.2 5.7 2 2 3 5 5 5 0 Uncharacterized coiled-coil protein (DUF2353) Shugoshin_N PF07558.11 PVD20041.1 - 9 6.3 29.9 0.16 11.9 2.4 6.1 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region YlqD PF11068.8 PVD20042.1 - 0.00038 20.8 9.3 0.00059 20.2 9.3 1.4 1 0 0 1 1 1 1 YlqD protein JIP_LZII PF16471.5 PVD20042.1 - 0.00061 19.9 9.5 0.018 15.2 1.0 2.7 2 1 1 3 3 3 2 JNK-interacting protein leucine zipper II Prefoldin_2 PF01920.20 PVD20042.1 - 0.0087 16.0 13.3 0.15 12.0 3.5 2.2 2 0 0 2 2 2 2 Prefoldin subunit Leu_zip PF15294.6 PVD20042.1 - 0.015 14.9 9.7 0.018 14.6 9.7 1.0 1 0 0 1 1 1 0 Leucine zipper Seryl_tRNA_N PF02403.22 PVD20042.1 - 0.016 15.5 8.4 0.07 13.4 8.4 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AIP3 PF03915.13 PVD20042.1 - 0.017 14.2 6.7 0.019 14.1 6.7 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 WXG100 PF06013.12 PVD20042.1 - 0.018 15.2 5.8 0.31 11.3 5.6 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG MATH PF00917.26 PVD20042.1 - 0.021 15.0 0.8 0.029 14.5 0.7 1.3 1 1 0 1 1 1 0 MATH domain FapA PF03961.13 PVD20042.1 - 0.025 13.2 6.2 0.029 13.0 6.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 PVD20042.1 - 0.029 14.7 10.7 0.053 13.9 10.6 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 PVD20042.1 - 0.03 13.2 8.7 0.042 12.7 8.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 PVD20042.1 - 0.039 14.4 7.2 0.055 13.9 7.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_32 PF13654.6 PVD20042.1 - 0.039 12.8 6.3 0.044 12.6 6.3 1.0 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 PVD20042.1 - 0.054 13.9 13.8 0.29 11.6 11.3 2.2 1 1 0 2 2 2 0 Cell division protein ZapB UvrA_DNA-bind PF17755.1 PVD20042.1 - 0.059 13.7 0.7 0.4 11.1 0.3 2.0 2 0 0 2 2 2 0 UvrA DNA-binding domain Spc24 PF08286.11 PVD20042.1 - 0.061 13.6 10.7 1.1 9.5 1.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMCO5 PF14992.6 PVD20042.1 - 0.061 12.9 8.4 0.079 12.5 8.4 1.2 1 0 0 1 1 1 0 TMCO5 family Fez1 PF06818.15 PVD20042.1 - 0.062 13.7 9.2 0.087 13.3 9.2 1.1 1 0 0 1 1 1 0 Fez1 SAS4 PF15460.6 PVD20042.1 - 0.063 13.4 5.2 0.12 12.5 5.0 1.5 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 TSC22 PF01166.18 PVD20042.1 - 0.14 12.5 8.2 2.2 8.7 1.2 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 PVD20042.1 - 0.18 12.1 11.2 0.25 11.6 4.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper PKcGMP_CC PF16808.5 PVD20042.1 - 0.19 11.6 6.8 0.34 10.8 0.1 2.9 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tup_N PF08581.10 PVD20042.1 - 0.19 12.0 15.1 0.078 13.3 6.1 2.3 1 1 0 2 2 2 0 Tup N-terminal LRRFIP PF09738.9 PVD20042.1 - 0.2 11.1 14.6 0.3 10.5 4.4 2.0 1 1 1 2 2 2 0 LRRFIP family DUF3450 PF11932.8 PVD20042.1 - 0.21 10.9 10.4 0.3 10.4 10.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 PVD20042.1 - 0.22 11.8 5.5 0.92 9.8 0.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) DASH_Dad2 PF08654.10 PVD20042.1 - 0.24 11.8 7.2 3.4 8.1 0.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 APG6_N PF17675.1 PVD20042.1 - 0.26 11.8 16.0 0.76 10.3 15.9 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 PVD20042.1 - 0.28 10.5 7.2 1.3 8.3 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 PVD20042.1 - 0.29 11.6 7.5 1.3 9.5 1.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 PVD20042.1 - 0.45 10.5 11.1 1.6 8.8 3.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 PVD20042.1 - 0.47 10.4 11.4 0.54 10.2 9.2 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain PI3K_P85_iSH2 PF16454.5 PVD20042.1 - 0.5 10.0 13.2 0.33 10.5 3.6 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CLZ PF16526.5 PVD20042.1 - 0.57 10.6 11.5 0.67 10.4 2.7 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GPS2_interact PF15784.5 PVD20042.1 - 0.57 10.7 6.6 0.71 10.3 3.8 2.0 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Csm1_N PF18504.1 PVD20042.1 - 0.76 10.2 13.0 0.12 12.7 2.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain CCDC74_C PF14917.6 PVD20042.1 - 0.88 10.1 7.9 4 8.0 7.8 1.9 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal DUF1664 PF07889.12 PVD20042.1 - 0.93 9.5 7.1 2.1 8.4 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 PVD20042.1 - 0.96 9.3 3.7 6.7 6.6 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 PVD20042.1 - 1.1 9.1 9.2 1.6 8.5 1.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Methyltransf_14 PF08484.11 PVD20042.1 - 1.6 8.5 4.7 0.87 9.4 1.0 1.9 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain YabA PF06156.13 PVD20042.1 - 2 9.1 9.6 80 4.0 9.5 2.2 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 PVD20042.1 - 2.5 8.7 10.2 8.8 6.9 1.8 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor IFP_35_N PF07334.13 PVD20042.1 - 3.1 7.9 8.0 2.4 8.3 2.7 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus OmpH PF03938.14 PVD20042.1 - 4.9 7.5 12.3 9.8 6.5 12.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.15 PVD20042.1 - 5 7.3 13.2 5.6 7.1 3.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Methyltransf_32 PF13679.6 PVD20043.1 - 3.2e-23 82.5 9.0 2.7e-22 79.5 9.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Homeodomain PF00046.29 PVD20043.1 - 0.51 10.2 1.7 2.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Homeodomain Fmp27_WPPW PF10359.9 PVD20044.1 - 0.00079 18.4 4.2 0.00084 18.3 4.2 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Herpes_BLRF2 PF05812.12 PVD20044.1 - 0.05 13.7 3.2 0.065 13.4 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Vps53_N PF04100.12 PVD20044.1 - 0.061 12.3 5.5 0.067 12.1 5.5 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal eIF-4B PF06273.11 PVD20044.1 - 0.065 12.3 0.8 0.073 12.1 0.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B FemAB PF02388.16 PVD20044.1 - 0.07 12.0 4.3 0.08 11.8 4.3 1.1 1 0 0 1 1 1 0 FemAB family TRAF_BIRC3_bd PF16673.5 PVD20044.1 - 0.19 11.5 6.0 6.5 6.6 6.0 2.3 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DUF2508 PF10704.9 PVD20044.1 - 0.49 10.6 3.6 0.71 10.1 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) FlaC_arch PF05377.11 PVD20044.1 - 0.95 9.9 8.6 20 5.7 8.6 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) MYO10_CC PF16735.5 PVD20044.1 - 1 9.5 7.4 0.52 10.4 3.1 2.1 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain DivIC PF04977.15 PVD20044.1 - 1.5 8.6 10.2 5.7 6.8 6.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Gp58 PF07902.11 PVD20044.1 - 2 6.6 7.8 2.4 6.4 7.8 1.0 1 0 0 1 1 1 0 gp58-like protein Allexi_40kDa PF05549.11 PVD20044.1 - 3.5 7.1 7.9 3.7 7.0 7.9 1.2 1 1 0 1 1 1 0 Allexivirus 40kDa protein SlyX PF04102.12 PVD20044.1 - 6.8 7.4 9.4 25 5.6 9.3 2.0 1 1 0 1 1 1 0 SlyX Siah-Interact_N PF09032.11 PVD20044.1 - 7 7.0 12.4 3.7 7.9 5.6 2.3 1 1 1 2 2 2 0 Siah interacting protein, N terminal TPR_1 PF00515.28 PVD20045.1 - 6.2e-21 73.3 17.1 0.013 15.3 0.1 13.6 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_17 PF13431.6 PVD20045.1 - 2e-19 68.5 20.2 2.5e-06 27.4 0.0 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20045.1 - 2.3e-19 67.9 32.9 0.0086 16.1 0.1 15.7 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD20045.1 - 9.1e-18 63.7 5.5 0.32 10.7 0.0 9.8 9 1 1 10 10 10 5 TPR repeat TPR_14 PF13428.6 PVD20045.1 - 3.9e-16 58.4 15.7 0.012 16.4 0.0 13.4 14 2 2 16 16 14 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD20045.1 - 3.5e-14 51.7 20.9 0.01 15.9 0.0 12.8 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD20045.1 - 2.3e-12 47.3 9.2 0.2 12.3 0.0 9.2 9 1 2 11 11 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 PVD20045.1 - 3.1e-08 33.2 21.3 0.00012 21.4 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD20045.1 - 4.9e-06 26.2 4.6 1.1 9.5 0.2 6.6 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD20045.1 - 2.5e-05 24.6 16.1 0.1 13.3 0.0 9.7 12 1 0 12 12 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD20045.1 - 0.00097 19.6 44.6 0.55 10.8 0.6 12.6 12 3 2 15 15 15 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD20045.1 - 0.0021 18.3 28.9 0.59 10.5 0.1 9.3 9 2 0 10 10 8 1 Tetratricopeptide repeat ChAPs PF09295.10 PVD20045.1 - 0.0038 16.3 15.1 0.056 12.4 1.8 4.3 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF4192 PF13830.6 PVD20045.1 - 0.011 15.8 0.0 0.13 12.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) SRP_TPR_like PF17004.5 PVD20045.1 - 0.012 15.7 1.5 0.048 13.7 0.4 2.8 2 1 0 2 2 1 0 Putative TPR-like repeat Sel1 PF08238.12 PVD20045.1 - 0.02 15.5 3.6 6.5 7.6 0.2 5.4 5 1 1 6 6 5 0 Sel1 repeat DUF1685 PF07939.11 PVD20045.1 - 0.082 12.7 0.8 3.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) FAT PF02259.23 PVD20045.1 - 1.1 8.4 22.2 2.9 7.0 0.2 5.0 4 1 1 5 5 5 0 FAT domain OmpH PF03938.14 PVD20046.1 - 0.25 11.7 8.0 0.84 10.0 8.0 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 PVD20046.1 - 0.6 10.5 8.1 1.7 9.0 8.1 1.8 1 0 0 1 1 1 0 YlqD protein MIP PF00230.20 PVD20047.1 - 2.3e-35 122.3 3.9 1.7e-34 119.5 3.4 1.9 2 0 0 2 2 2 1 Major intrinsic protein Ig_3 PF13927.6 PVD20048.1 - 1e-25 90.1 1.4 1.3e-12 48.2 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD20048.1 - 1.1e-23 83.0 0.2 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD20048.1 - 1.1e-15 57.6 0.2 9.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD20048.1 - 9.9e-15 54.7 1.3 6.9e-07 29.5 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD20048.1 - 5.5e-07 29.7 0.8 0.029 14.5 0.1 2.5 2 1 1 3 3 3 2 Immunoglobulin V-set domain IBR PF01485.21 PVD20050.1 - 1.2e-20 73.5 46.7 5.6e-15 55.3 7.8 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PVD20050.1 - 4.7e-05 23.1 4.9 4.7e-05 23.1 4.9 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD20050.1 - 0.00029 21.1 5.5 0.00029 21.1 5.5 5.1 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 PVD20050.1 - 0.00076 19.3 6.0 0.00076 19.3 6.0 5.2 5 1 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD20050.1 - 0.0011 19.1 10.0 0.0073 16.4 3.5 4.9 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD20050.1 - 0.0079 16.1 7.3 0.0079 16.1 7.3 4.1 2 1 1 3 3 3 1 zinc-RING finger domain adh_short PF00106.25 PVD20051.1 - 2e-39 135.1 0.2 4.4e-39 134.0 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase MaoC_dehydratas PF01575.19 PVD20051.1 - 5.6e-35 119.6 0.0 1.2e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.6 PVD20051.1 - 3.5e-32 111.8 0.2 6.9e-32 110.9 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 PVD20051.1 - 8.1e-22 77.6 0.1 2.1e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 PVD20051.1 - 2.2e-15 57.1 0.1 3.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 PVD20051.1 - 4.5e-07 30.1 0.0 1.2e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 PVD20051.1 - 0.00059 20.1 0.1 0.0018 18.6 0.1 1.8 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal zf-H2C2_2 PF13465.6 PVD20052.1 - 7.5e-13 48.3 26.7 0.00036 20.8 1.1 5.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD20052.1 - 1e-08 35.1 33.7 0.18 12.3 0.7 6.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD20052.1 - 1e-05 25.1 29.1 0.0083 15.9 0.5 5.6 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD20052.1 - 0.0089 16.8 48.7 0.023 15.5 0.7 7.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_9 PF16293.5 PVD20052.1 - 0.02 14.7 0.1 0.02 14.7 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 PVD20052.1 - 2.7 8.1 19.0 78 3.4 3.3 4.2 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 PVD20052.1 - 5.1 7.5 22.9 0.13 12.7 5.8 4.3 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4722 PF15849.5 PVD20052.1 - 8.4 6.1 8.6 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4722) Ribosomal_L36e PF01158.18 PVD20053.1 - 9.5e-42 141.2 7.4 1.1e-41 141.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF234 PF03008.14 PVD20053.1 - 0.074 13.5 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function C2 PF00168.30 PVD20054.1 - 4.1e-71 235.8 0.4 2.8e-23 82.1 0.0 3.4 3 0 0 3 3 3 3 C2 domain MLVIN_C PF18697.1 PVD20054.1 - 9.6e-05 22.4 1.4 0.22 11.6 0.0 3.5 3 0 0 3 3 3 2 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Pex24p PF06398.11 PVD20054.1 - 0.0044 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4497 PF14924.6 PVD20054.1 - 0.031 14.8 0.0 4.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) PRT_C PF08372.10 PVD20054.1 - 0.079 12.7 3.8 0.33 10.7 0.1 2.4 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal 2OG-FeII_Oxy_4 PF13661.6 PVD20054.1 - 0.088 13.5 0.0 0.31 11.7 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Conotoxin PF02950.17 PVD20054.1 - 0.24 12.4 0.6 4.4 8.4 0.2 2.8 2 0 0 2 2 2 0 Conotoxin LegC3_N PF18654.1 PVD20054.1 - 0.31 10.2 4.9 0.74 9.0 4.9 1.5 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain E7 PF00527.18 PVD20054.1 - 1.5 9.1 6.8 0.31 11.3 2.1 2.2 2 0 0 2 2 2 0 E7 protein, Early protein FAM176 PF14851.6 PVD20054.1 - 7.6 6.2 10.4 0.32 10.7 0.3 2.6 2 1 0 2 2 2 0 FAM176 family Cpn60_TCP1 PF00118.24 PVD20056.1 - 1.1e-162 542.2 4.4 1.3e-162 541.9 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1725 PF08333.11 PVD20056.1 - 0.14 11.9 0.6 0.37 10.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Pkinase_Tyr PF07714.17 PVD20057.1 - 1.7e-39 135.7 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD20057.1 - 9.3e-24 84.2 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PVD20057.1 - 0.015 14.7 0.0 0.056 12.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.21 PVD20058.1 - 1.3e-98 329.3 0.0 4.2e-65 219.5 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 PVD20058.1 - 1.9e-72 244.2 0.0 2.7e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 PVD20058.1 - 1.6e-25 89.1 0.0 2.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 PVD20058.1 - 2.2e-18 66.2 0.0 7.1e-18 64.6 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 PVD20058.1 - 5.9e-13 49.3 0.0 1.3e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 PVD20058.1 - 0.15 12.1 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.27 PVD20059.1 - 0.00053 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3697 PF12478.8 PVD20060.1 - 3.1e-11 43.2 1.8 1.3e-10 41.2 1.8 2.2 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 DUF1296 PF06972.11 PVD20060.1 - 0.0021 18.2 0.1 0.005 16.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Ion_trans_2 PF07885.16 PVD20061.1 - 4.8e-36 122.6 17.9 2.8e-19 68.9 0.5 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 PVD20061.1 - 1.3e-07 31.2 5.4 0.0034 16.7 1.0 2.4 2 1 0 2 2 2 2 Ion transport protein Shisa PF13908.6 PVD20061.1 - 0.0002 21.6 1.6 0.029 14.6 1.0 3.0 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 PVD20061.1 - 0.014 16.0 6.4 0.61 10.8 2.1 2.7 2 1 0 2 2 2 0 WW domain-binding protein 1 eIF3_subunit PF08597.10 PVD20062.1 - 1.7e-09 37.9 15.4 1.7e-09 37.9 15.4 3.4 3 1 1 4 4 4 1 Translation initiation factor eIF3 subunit S4_2 PF13275.6 PVD20062.1 - 0.094 12.6 2.9 1.2 9.0 0.0 3.9 4 0 0 4 4 4 0 S4 domain cNMP_binding PF00027.29 PVD20064.1 - 1.6e-47 159.5 0.1 3.8e-24 84.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 PVD20064.1 - 4.3e-10 39.1 0.0 8.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AAA PF00004.29 PVD20065.1 - 1.4e-74 248.8 0.0 4.6e-38 130.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD20065.1 - 6.7e-26 89.8 0.1 3.1e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PVD20065.1 - 9.6e-17 61.9 0.3 9.3e-06 26.1 0.5 4.0 2 2 1 3 3 3 3 AAA ATPase domain RuvB_N PF05496.12 PVD20065.1 - 9.6e-12 44.9 0.0 0.00012 21.9 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PVD20065.1 - 4e-11 43.1 0.1 0.00052 20.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PVD20065.1 - 4.3e-08 33.3 0.0 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PVD20065.1 - 4.4e-08 33.2 0.2 0.081 12.8 0.0 4.7 5 0 0 5 5 5 2 NACHT domain AAA_25 PF13481.6 PVD20065.1 - 7.5e-08 32.2 2.3 0.088 12.4 0.0 4.8 4 2 2 6 6 5 2 AAA domain TIP49 PF06068.13 PVD20065.1 - 1.9e-07 30.7 0.0 0.00029 20.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 PVD20065.1 - 2.8e-07 30.8 0.0 0.037 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PVD20065.1 - 5.3e-07 29.6 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 PVD20065.1 - 7.5e-07 28.6 0.0 0.0019 17.4 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function (DUF815) Rad17 PF03215.15 PVD20065.1 - 8.5e-07 29.1 0.2 0.14 12.1 0.0 3.2 2 1 1 3 3 3 2 Rad17 P-loop domain RNA_helicase PF00910.22 PVD20065.1 - 1.5e-06 28.5 0.0 0.066 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 PVD20065.1 - 2.8e-06 27.5 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PVD20065.1 - 3.2e-06 27.5 3.9 0.18 12.1 0.1 4.2 3 2 1 4 4 3 2 AAA domain AAA_11 PF13086.6 PVD20065.1 - 4.5e-06 26.6 0.0 0.025 14.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PVD20065.1 - 7.2e-06 26.6 0.0 0.068 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 PVD20065.1 - 1.3e-05 25.2 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PVD20065.1 - 1.8e-05 25.3 0.1 0.45 11.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 PVD20065.1 - 2.2e-05 24.8 0.2 0.25 11.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.15 PVD20065.1 - 6.2e-05 23.0 0.0 0.7 9.8 0.0 3.3 2 1 1 3 3 2 2 NTPase AAA_24 PF13479.6 PVD20065.1 - 0.00011 22.0 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 PVD20065.1 - 0.00011 22.2 0.0 0.077 12.9 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 PVD20065.1 - 0.00023 20.6 0.0 0.35 10.2 0.0 2.8 2 0 0 2 2 2 2 KaiC AAA_29 PF13555.6 PVD20065.1 - 0.00024 20.8 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 PVD20065.1 - 0.00025 21.5 0.2 0.49 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 PVD20065.1 - 0.00029 20.3 0.5 0.67 9.3 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PVD20065.1 - 0.00034 20.2 0.0 0.58 9.6 0.0 2.5 3 0 0 3 3 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD20065.1 - 0.00036 20.3 0.0 0.56 9.9 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.6 PVD20065.1 - 0.00093 19.5 1.2 1.7 9.0 0.2 3.5 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PVD20065.1 - 0.0024 17.6 0.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PVD20065.1 - 0.0027 16.9 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 PVD20065.1 - 0.0029 17.0 0.0 14 5.0 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein cobW PF02492.19 PVD20065.1 - 0.0031 17.1 0.9 4.2 6.9 0.1 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 PVD20065.1 - 0.0033 16.7 0.1 2.7 7.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin SRPRB PF09439.10 PVD20065.1 - 0.0087 15.5 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_3 PF07726.11 PVD20065.1 - 0.011 15.6 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PVD20065.1 - 0.015 15.2 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 PVD20065.1 - 0.017 14.9 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 PVD20065.1 - 0.027 13.7 0.0 4.3 6.5 0.0 3.4 3 1 0 4 4 4 0 KAP family P-loop domain MMR_HSR1 PF01926.23 PVD20065.1 - 0.028 14.5 0.2 11 6.2 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 PVD20065.1 - 0.054 12.6 0.0 2.3 7.2 0.0 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein SRP54 PF00448.22 PVD20065.1 - 0.069 12.8 0.1 7.8 6.1 0.0 3.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PVD20065.1 - 0.075 13.5 0.3 1.7 9.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 PVD20065.1 - 0.16 11.5 0.0 26 4.3 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Ribosomal_L37 PF08561.10 PVD20066.1 - 3.4e-07 30.8 5.4 9.2e-07 29.4 5.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF1180 PF06679.12 PVD20067.1 - 1.9e-22 80.4 0.0 2.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM132D_C PF15706.5 PVD20067.1 - 0.0085 15.9 0.0 0.091 12.5 0.0 2.1 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF3397 PF11877.8 PVD20067.1 - 0.067 13.4 0.9 0.091 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DUF2681 PF10883.8 PVD20067.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3989 PF13150.6 PVD20067.1 - 0.15 11.8 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) COX7a PF02238.15 PVD20067.1 - 2.7 8.5 5.4 1.8 9.1 3.7 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VII Ribosomal_L4 PF00573.22 PVD20068.1 - 2.8e-40 138.0 1.4 3.3e-40 137.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 PVD20068.1 - 9.4e-26 89.7 6.1 9.4e-26 89.7 6.1 2.4 3 0 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain GCP_C_terminal PF04130.13 PVD20069.1 - 3.4e-61 207.4 8.3 3.4e-61 207.4 8.3 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PVD20069.1 - 4.4e-46 157.9 1.3 6.2e-46 157.4 0.1 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal IMS PF00817.20 PVD20070.1 - 7.3e-41 139.6 0.0 2.3e-40 138.1 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 PVD20070.1 - 1.1e-12 48.6 0.2 2.4e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 PVD20070.1 - 9.9e-08 31.2 4.6 0.0037 16.7 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin binding region Ephrin_rec_like PF07699.13 PVD20071.1 - 4.4e-07 29.6 83.3 5.2e-05 22.9 6.3 140.0 91 32 47 141 141 141 99 Putative ephrin-receptor like Arf PF00025.21 PVD20073.1 - 3.6e-33 114.4 0.0 5.1e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD20073.1 - 4.4e-06 26.2 0.0 1e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PVD20073.1 - 0.00041 20.0 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PVD20073.1 - 0.00053 19.3 0.5 0.54 9.4 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 PVD20073.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Reovirus_Mu2 PF07781.11 PVD20073.1 - 0.082 11.3 0.0 0.099 11.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 Gtr1_RagA PF04670.12 PVD20073.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PVD20073.1 - 0.13 12.6 0.1 0.45 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PVD20073.1 - 0.17 12.4 0.3 0.26 11.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter zf-RING_2 PF13639.6 PVD20074.1 - 1e-15 57.7 20.7 1.7e-13 50.6 9.3 2.2 2 0 0 2 2 2 2 Ring finger domain zinc_ribbon_9 PF14369.6 PVD20074.1 - 1.2e-08 35.1 2.4 1.2e-08 35.1 2.4 2.7 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 PVD20074.1 - 2.7e-08 33.5 8.6 2.7e-08 33.5 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD20074.1 - 2.9e-08 33.4 13.9 5.1e-05 23.0 5.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PVD20074.1 - 6.3e-08 32.2 8.0 6.3e-08 32.2 8.0 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PVD20074.1 - 3e-06 27.1 2.3 3e-06 27.1 2.3 3.0 2 2 2 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD20074.1 - 2e-05 24.5 6.6 2e-05 24.5 6.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD20074.1 - 3.6e-05 24.0 10.6 3.6e-05 24.0 10.6 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PVD20074.1 - 8.8e-05 22.3 7.9 8.8e-05 22.3 7.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PVD20074.1 - 0.0016 18.5 3.4 0.0016 18.5 3.4 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PVD20074.1 - 0.0078 16.1 16.0 0.016 15.0 5.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 HypA PF01155.19 PVD20074.1 - 0.0081 16.2 8.1 0.026 14.6 1.1 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 PVD20074.1 - 0.015 15.1 0.4 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PVD20074.1 - 0.062 13.1 16.2 0.034 13.9 5.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 PVD20074.1 - 0.15 12.0 9.9 0.15 12.0 0.5 2.8 2 1 0 2 2 2 0 zinc-ribbons LIM PF00412.22 PVD20074.1 - 0.33 11.2 11.6 0.35 11.1 3.4 3.4 2 2 1 3 3 3 0 LIM domain DZR PF12773.7 PVD20074.1 - 0.56 10.3 11.5 0.13 12.3 2.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon Rpr2 PF04032.16 PVD20074.1 - 2.1 8.7 5.0 2.2 8.6 0.7 2.6 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Prok-RING_1 PF14446.6 PVD20074.1 - 5 7.1 13.2 33 4.5 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Elf1 PF05129.13 PVD20074.1 - 7.7 6.6 11.4 3.8 7.6 0.1 3.6 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like ELL PF10390.9 PVD20075.1 - 3.9e-66 223.4 0.0 7.4e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 PVD20075.1 - 2.3e-12 47.5 3.5 2.3e-12 47.5 3.5 1.9 2 0 0 2 2 2 1 Occludin homology domain S36_mt PF10937.8 PVD20077.1 - 0.0011 20.6 0.0 0.0016 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial YEATS PF03366.16 PVD20078.1 - 1.1e-25 89.4 0.1 1.9e-25 88.6 0.1 1.5 1 0 0 1 1 1 1 YEATS family AHD PF17793.1 PVD20078.1 - 2.4e-11 43.2 0.1 4.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 ANC1 homology domain (AHD) F5_F8_type_C PF00754.25 PVD20078.1 - 4.2e-05 23.7 0.0 0.00015 21.8 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF167 PF02594.16 PVD20079.1 - 1.2e-24 86.2 0.3 1.6e-24 85.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RNase_II_C_S1 PF18614.1 PVD20079.1 - 0.013 15.4 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Cu-oxidase_4 PF02578.15 PVD20080.1 - 2.3e-47 161.5 0.1 1.6e-36 126.1 0.2 2.2 2 0 0 2 2 2 2 Multi-copper polyphenol oxidoreductase laccase PEP_mutase PF13714.6 PVD20080.1 - 0.014 14.9 0.4 0.62 9.5 0.0 2.7 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase WND PF07861.11 PVD20080.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 WisP family N-Terminal Region ASC PF00858.24 PVD20081.1 - 9.7e-15 54.5 0.2 1.1e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2516 PF10724.9 PVD20081.1 - 0.048 14.0 0.1 0.42 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) ASC PF00858.24 PVD20082.1 - 8.4e-17 61.3 0.4 9.7e-17 61.0 0.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 PVD20083.1 - 2.8e-57 194.7 0.9 3.1e-57 194.5 0.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Pkinase PF00069.25 PVD20084.1 - 1.5e-61 208.1 0.0 1.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20084.1 - 2.1e-33 115.7 0.0 2.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 PVD20084.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 PVD20084.1 - 0.006 15.4 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD20084.1 - 0.021 13.8 0.0 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain NUDIX PF00293.28 PVD20085.1 - 3.1e-16 59.6 0.1 3.8e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Frataxin_Cyay PF01491.16 PVD20086.1 - 6.1e-36 122.8 0.0 7.2e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Arrestin_C PF02752.22 PVD20087.1 - 5.1e-19 69.0 0.0 8.4e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD20087.1 - 0.0006 19.9 0.2 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain bZIP_1 PF00170.21 PVD20088.1 - 2.7e-16 59.4 10.2 5.3e-16 58.5 10.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD20088.1 - 1.2e-09 38.0 4.5 1.2e-09 38.0 4.5 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 PVD20088.1 - 5.5e-06 26.8 6.6 1.2e-05 25.7 6.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Imm43 PF15570.6 PVD20088.1 - 0.032 14.2 0.2 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 43 JMY PF15871.5 PVD20088.1 - 0.078 12.3 2.6 0.13 11.5 2.6 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein ZapB PF06005.12 PVD20088.1 - 3.9 8.0 8.4 0.2 12.1 0.4 2.7 3 0 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 PVD20088.1 - 8.9 7.0 8.8 2.3 8.9 2.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA adh_short PF00106.25 PVD20089.1 - 8.7e-34 116.7 4.8 4.3e-26 91.6 1.1 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD20089.1 - 4.4e-25 88.6 0.5 2.4e-23 82.9 0.5 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD20089.1 - 6e-06 26.3 0.4 1.3e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PVD20089.1 - 0.0014 18.2 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2855 PF11017.8 PVD20089.1 - 0.045 13.5 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) THF_DHG_CYH_C PF02882.19 PVD20089.1 - 0.061 12.6 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Linker_histone PF00538.19 PVD20090.1 - 1.5e-06 28.4 0.0 3.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF4777 PF16007.5 PVD20090.1 - 0.096 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) SAE2 PF08573.10 PVD20090.1 - 0.37 11.9 12.3 0.36 12.0 11.2 1.5 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus NARP1 PF12569.8 PVD20090.1 - 8.7 5.1 8.0 13 4.5 8.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Linker_histone PF00538.19 PVD20091.1 - 4e-06 27.1 0.0 1.5e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family Stork_head PF10264.9 PVD20091.1 - 0.0052 16.9 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain PARP PF00644.20 PVD20092.1 - 4.3e-11 42.8 0.4 8.8e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 PVD20092.1 - 4.2e-07 30.1 0.1 1e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 ARTD15 N-terminal domain Microvir_lysis PF04517.12 PVD20092.1 - 0.042 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus PWWP PF00855.17 PVD20093.1 - 1.7e-07 31.6 0.0 5.6e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Rad9_Rad53_bind PF08605.10 PVD20093.1 - 0.026 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Tudor_2 PF18104.1 PVD20093.1 - 0.084 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain ABC_tran PF00005.27 PVD20094.1 - 2.7e-34 118.6 0.1 9.7e-17 61.8 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 PVD20094.1 - 1e-26 94.2 33.5 3.4e-16 59.7 13.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 PVD20094.1 - 7.6e-05 22.8 0.4 0.055 13.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD20094.1 - 8.3e-05 23.0 0.1 0.05 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 PVD20094.1 - 0.0027 17.2 0.0 6.9 6.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain TniQ PF06527.11 PVD20094.1 - 0.068 13.9 1.8 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 TniQ FeoB_N PF02421.18 PVD20094.1 - 0.076 12.5 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3148 PF11347.8 PVD20094.1 - 0.078 12.7 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) MobB PF03205.14 PVD20094.1 - 0.16 11.9 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 PVD20094.1 - 2.2 8.3 5.7 1.8 8.6 0.2 3.1 3 0 0 3 3 3 0 Dynamin family WD40 PF00400.32 PVD20095.1 - 1.1e-26 92.5 14.5 1.7e-05 25.5 0.2 9.7 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD20095.1 - 3.5e-05 24.0 2.4 0.046 14.0 0.1 4.5 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RasGAP PF00616.19 PVD20096.1 - 3e-56 190.4 0.1 1.2e-55 188.5 0.1 2.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 PVD20096.1 - 1.9e-36 125.2 10.0 1.9e-36 125.2 10.0 4.3 4 1 1 5 5 5 1 RasGAP C-terminus IQ PF00612.27 PVD20096.1 - 3.3e-17 60.6 14.3 0.00022 20.7 0.0 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.31 PVD20096.1 - 1.1e-16 60.9 0.6 1.1e-15 57.7 0.0 3.1 3 0 0 3 3 3 1 Calponin homology (CH) domain DUF3360 PF11840.8 PVD20096.1 - 0.0057 15.4 0.3 0.0083 14.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3360) Ribonuc_2-5A PF06479.12 PVD20096.1 - 0.014 15.5 1.6 0.07 13.3 1.6 2.2 1 0 0 1 1 1 0 Ribonuclease 2-5A WW PF00397.26 PVD20096.1 - 0.042 14.0 1.2 0.11 12.7 1.2 1.7 1 0 0 1 1 1 0 WW domain Baculo_PEP_C PF04513.12 PVD20097.1 - 0.44 10.6 28.5 1.5 8.8 0.6 4.6 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.12 PVD20097.1 - 0.54 10.4 4.8 5.6 7.2 0.6 3.6 3 0 0 3 3 3 0 MbeD/MobD like Apolipoprotein PF01442.18 PVD20097.1 - 1.3 8.9 30.9 0.14 12.0 15.5 3.5 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain Sulfatase_C PF14707.6 PVD20097.1 - 3.1 8.6 8.4 6.6 7.5 0.1 4.0 2 1 3 5 5 5 0 C-terminal region of aryl-sulfatase CdvA PF18822.1 PVD20097.1 - 3.2 7.6 31.1 0.98 9.3 0.6 5.9 4 2 2 7 7 7 0 CdvA-like coiled-coil domain FUSC PF04632.12 PVD20097.1 - 3.2 6.2 9.3 2.2 6.7 7.0 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 PVD20097.1 - 3.4 7.8 32.8 0.4 10.9 4.6 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Plk4_PB2 PF18409.1 PVD20097.1 - 7.8 7.2 13.3 9.2 7.0 0.4 3.6 2 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 EnY2 PF10163.9 PVD20097.1 - 8.4 6.8 11.2 0.34 11.3 1.3 3.4 4 0 0 4 4 4 0 Transcription factor e(y)2 zf-RING_UBOX PF13445.6 PVD20098.1 - 1.1e-09 38.2 6.4 1.1e-09 38.2 6.4 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD20098.1 - 5.1e-09 35.9 7.9 5.1e-09 35.9 7.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD20098.1 - 1.1e-06 28.9 7.0 1.1e-06 28.9 7.0 3.6 3 1 1 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD20098.1 - 2e-06 27.6 8.1 2e-06 27.6 8.1 2.9 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD20098.1 - 3.8e-06 26.6 5.9 3.8e-06 26.6 5.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD20098.1 - 1.9e-05 24.7 9.5 1.9e-05 24.7 9.5 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD20098.1 - 0.00028 20.6 9.8 0.00028 20.6 9.8 3.3 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD20098.1 - 0.0016 18.5 5.4 0.0016 18.5 5.4 3.4 3 0 0 3 3 3 1 B-box zinc finger Prok-RING_4 PF14447.6 PVD20098.1 - 0.0031 17.4 6.3 0.0031 17.4 6.3 3.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD20098.1 - 0.012 15.3 8.1 0.03 14.1 4.3 3.3 3 0 0 3 3 3 0 RING-like zinc finger FYVE_2 PF02318.16 PVD20098.1 - 0.016 15.4 10.4 0.61 10.3 2.9 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-4CXXC_R1 PF10497.9 PVD20098.1 - 0.77 10.0 7.6 0.22 11.7 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.6 PVD20098.1 - 8.6 6.2 13.7 0.97 9.3 6.5 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PKcGMP_CC PF16808.5 PVD20099.1 - 0.011 15.5 4.3 0.011 15.5 4.3 5.6 4 2 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4094 PF13334.6 PVD20099.1 - 0.04 14.3 1.2 0.04 14.3 1.2 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) XLF PF09302.11 PVD20099.1 - 0.19 11.9 8.9 2.9 8.0 2.6 3.1 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF641 PF04859.12 PVD20099.1 - 0.34 11.2 22.7 0.19 12.1 1.3 3.7 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) HAP1_N PF04849.13 PVD20099.1 - 0.44 9.7 31.2 0.95 8.6 22.0 2.7 3 0 0 3 3 3 0 HAP1 N-terminal conserved region DUF948 PF06103.11 PVD20099.1 - 1.7 8.9 6.3 26 5.2 1.8 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cob_adeno_trans PF01923.18 PVD20099.1 - 2.1 8.4 10.8 0.67 10.1 3.8 2.6 1 1 0 2 2 2 0 Cobalamin adenosyltransferase UPF0231 PF06062.11 PVD20099.1 - 2.2 8.6 6.0 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) HMMR_N PF15905.5 PVD20099.1 - 2.4 7.5 35.8 0.42 10.0 0.4 2.9 3 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 PVD20099.1 - 5.6 7.4 16.4 2.1 8.8 3.2 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 PVD20099.1 - 6.7 7.4 23.9 5.1 7.8 1.5 4.5 2 1 3 5 5 5 0 SlyX Fib_alpha PF08702.10 PVD20099.1 - 8.7 6.5 23.0 22 5.2 1.6 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CBM_14 PF01607.24 PVD20100.1 - 3.6e-06 27.1 1.3 6e-06 26.3 1.3 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Nop14 PF04147.12 PVD20100.1 - 4.1 5.5 17.4 6.3 4.9 17.4 1.2 1 0 0 1 1 1 0 Nop14-like family Trypsin PF00089.26 PVD20101.1 - 1.4e-57 195.0 0.4 1.6e-57 194.8 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD20101.1 - 1e-06 29.7 0.0 1.5e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD20101.1 - 0.023 15.1 0.1 0.072 13.5 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) DUF5583 PF17821.1 PVD20101.1 - 0.053 13.5 0.2 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Sema PF01403.19 PVD20103.1 - 1.9e-125 419.0 0.0 2.3e-125 418.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 PVD20103.1 - 0.00059 20.3 8.6 0.00059 20.3 8.6 2.2 2 0 0 2 2 2 1 Plexin repeat AlaE PF06610.13 PVD20103.1 - 0.071 13.1 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 L-alanine exporter SIR2 PF02146.17 PVD20105.1 - 2.1e-22 79.9 0.7 1e-14 54.8 0.1 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 PVD20105.1 - 0.0045 16.7 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Brr6_like_C_C PF10104.9 PVD20105.1 - 0.18 11.6 1.2 0.31 10.8 1.2 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain RNA_pol_Rpc82 PF05645.13 PVD20106.1 - 1.1e-30 107.3 0.2 9.9e-28 97.6 0.1 3.2 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 PVD20106.1 - 2.6e-07 30.4 3.3 0.00013 21.8 0.2 4.0 4 1 0 4 4 4 1 TFIIE alpha subunit HTH_9 PF08221.11 PVD20106.1 - 7.4e-05 22.8 3.3 0.00088 19.3 0.2 3.8 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 PVD20106.1 - 0.0061 16.4 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB SMC_ScpB PF04079.16 PVD20106.1 - 0.017 14.7 0.3 0.36 10.4 0.0 2.6 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB Skp1 PF01466.19 PVD20106.1 - 0.14 12.2 0.3 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain AbLIM_anchor PF16182.5 PVD20108.1 - 0.00096 19.1 5.0 0.0013 18.6 5.0 1.2 1 0 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM HBS1_N PF08938.10 PVD20109.1 - 0.00076 19.7 0.2 0.36 11.2 0.0 2.7 2 0 0 2 2 2 2 HBS1 N-terminus UBA PF00627.31 PVD20109.1 - 0.028 14.3 0.0 0.57 10.2 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain zf-CHY PF05495.12 PVD20110.1 - 2.1e-11 44.2 27.4 6.8e-11 42.5 14.8 3.9 3 0 0 3 3 3 2 CHY zinc finger zf-CCCH PF00642.24 PVD20110.1 - 6.7e-09 35.4 34.6 0.0001 22.1 5.3 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PVD20110.1 - 2.2e-08 33.7 40.2 7.2e-06 25.7 6.4 4.4 4 0 0 4 4 4 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD20110.1 - 1.4e-07 31.3 41.4 0.0013 18.8 8.5 4.2 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 PVD20110.1 - 1.2e-06 29.2 18.2 0.0017 19.0 0.2 4.5 5 0 0 5 5 5 3 Torus domain zf-CCCH_2 PF14608.6 PVD20110.1 - 0.29 11.7 32.5 0.17 12.4 6.9 4.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CDC45 PF02724.14 PVD20110.1 - 2.4 6.4 26.4 0.048 12.0 11.1 2.3 2 0 0 2 2 2 0 CDC45-like protein IKI3 PF04762.12 PVD20111.1 - 5.5e-262 871.9 0.5 3.8e-235 783.1 0.0 2.4 2 1 1 3 3 3 2 IKI3 family ANAPC4_WD40 PF12894.7 PVD20111.1 - 3.3e-05 24.1 0.1 28 5.1 0.0 5.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain POX PF07526.11 PVD20111.1 - 0.015 15.9 0.1 0.051 14.2 0.1 1.8 1 0 0 1 1 1 0 Associated with HOX Se-cys_synth_N PF12390.8 PVD20111.1 - 0.15 12.3 0.1 0.92 9.8 0.1 2.4 1 0 0 1 1 1 0 Selenocysteine synthase N terminal MAT1 PF06391.13 PVD20111.1 - 0.44 10.3 3.3 1 9.2 3.3 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 C1q PF00386.21 PVD20112.1 - 4.3e-10 39.9 1.5 5e-10 39.7 0.1 1.9 2 0 0 2 2 1 1 C1q domain zf-RING_5 PF14634.6 PVD20112.1 - 1.5e-08 34.4 7.0 1.5e-08 34.4 7.0 4.4 3 2 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD20112.1 - 1e-07 31.8 3.2 1e-07 31.8 3.2 4.1 5 0 0 5 5 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD20112.1 - 5.4e-06 26.2 1.9 5.4e-06 26.2 1.9 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD20112.1 - 0.00076 19.3 2.4 0.00076 19.3 2.4 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD20112.1 - 0.00079 19.5 9.5 0.00079 19.5 9.5 4.1 4 0 0 4 4 3 1 B-box zinc finger zf-RING_2 PF13639.6 PVD20112.1 - 0.00086 19.6 10.6 0.00086 19.6 10.6 5.2 4 1 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 PVD20112.1 - 0.0033 17.1 4.4 0.0033 17.1 4.4 2.8 2 0 0 2 2 2 1 RING-like zinc finger RasGAP_C PF03836.15 PVD20112.1 - 0.015 15.4 3.0 0.015 15.4 3.0 2.3 2 1 0 2 2 2 0 RasGAP C-terminus DUF5082 PF16888.5 PVD20112.1 - 0.021 15.1 6.6 3.3 8.0 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) OmpH PF03938.14 PVD20112.1 - 0.3 11.4 11.1 1.4 9.2 5.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 PVD20112.1 - 0.33 10.5 10.0 0.77 9.3 2.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cob_adeno_trans PF01923.18 PVD20112.1 - 1.2 9.2 5.9 0.89 9.7 1.0 2.5 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Apolipoprotein PF01442.18 PVD20112.1 - 1.5 8.6 10.9 5.5 6.8 5.3 2.8 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD20112.1 - 2.7 8.0 6.6 12 5.9 1.3 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 PVD20112.1 - 2.9 8.4 8.0 43 4.7 4.5 3.4 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4449 PF14613.6 PVD20112.1 - 6.5 6.8 10.5 5.9 7.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Jiraiya PF15038.6 PVD20113.1 - 1.4e-43 148.3 7.2 3.4e-40 137.2 4.4 2.1 2 0 0 2 2 2 2 Jiraiya Orai-1 PF07856.12 PVD20113.1 - 0.032 13.9 4.8 0.095 12.4 3.8 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity Clc-like PF07062.12 PVD20113.1 - 4.6 6.7 9.5 0.15 11.5 3.1 1.7 2 0 0 2 2 2 0 Clc-like Cation_efflux PF01545.21 PVD20114.1 - 1.6e-44 152.0 15.9 1.6e-44 152.0 15.9 3.8 3 1 0 3 3 3 1 Cation efflux family TRAP_beta PF05753.14 PVD20116.1 - 2.2e-68 229.2 0.0 3e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) zf-CCHC PF00098.23 PVD20117.1 - 8.4e-08 32.0 14.6 0.0031 17.5 0.6 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 PVD20117.1 - 0.0041 16.8 11.7 0.062 13.1 0.1 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_5 PF14787.6 PVD20117.1 - 0.17 11.7 0.4 0.17 11.7 0.4 2.7 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger CKS PF01111.19 PVD20118.1 - 3.8e-29 100.7 2.5 3.8e-29 100.7 2.5 1.9 2 1 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioesterase PF00975.20 PVD20118.1 - 4.9e-05 23.5 0.1 7.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 PVD20118.1 - 0.00012 21.8 0.1 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD20118.1 - 0.0003 21.4 0.0 0.0004 21.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_trans_4_4 PF13579.6 PVD20118.1 - 0.033 14.6 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Peptidase_S9 PF00326.21 PVD20118.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PID PF00640.23 PVD20119.1 - 3.3e-37 127.7 0.0 5.5e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 PVD20119.1 - 3.8e-13 49.3 0.0 1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Nuc_sug_transp PF04142.15 PVD20120.1 - 1.4e-32 113.2 10.1 1.9e-32 112.7 10.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PVD20120.1 - 1.7e-06 27.5 2.8 2.8e-06 26.8 2.8 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PVD20120.1 - 0.0067 16.6 13.5 0.011 15.9 4.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF3169 PF11368.8 PVD20120.1 - 0.017 14.6 6.3 0.15 11.6 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Cactin_mid PF10312.9 PVD20121.1 - 1.9e-64 217.1 5.7 1.9e-64 217.1 5.7 2.6 2 1 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 PVD20121.1 - 5.5e-50 168.5 11.6 1e-49 167.6 11.6 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein ApoL PF05461.11 PVD20122.1 - 0.0053 16.1 6.9 0.0091 15.4 4.3 2.0 1 1 0 2 2 2 1 Apolipoprotein L DUF2207 PF09972.9 PVD20122.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LicD PF04991.13 PVD20123.1 - 4.6e-15 56.4 0.5 6e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 LicD family DUF1235 PF06822.12 PVD20123.1 - 0.013 14.8 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) LicD PF04991.13 PVD20124.1 - 9.2e-14 52.1 4.7 7.6e-10 39.3 0.2 2.6 2 1 1 3 3 3 2 LicD family PRA1 PF03208.19 PVD20124.1 - 0.075 12.7 1.2 0.16 11.6 0.2 1.9 1 1 1 2 2 2 0 PRA1 family protein AI-2E_transport PF01594.16 PVD20124.1 - 4.2 6.4 7.1 5.7 6.0 7.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter LicD PF04991.13 PVD20125.1 - 1.2e-10 41.9 1.0 2.9e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 LicD family DUF1235 PF06822.12 PVD20125.1 - 0.025 13.9 0.3 0.041 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) ApoL PF05461.11 PVD20126.1 - 1.5e-06 27.8 10.0 3.1e-05 23.4 10.0 2.1 1 1 0 1 1 1 1 Apolipoprotein L DUF2207 PF09972.9 PVD20126.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF677 PF05055.12 PVD20126.1 - 1.3 7.8 7.2 0.11 11.4 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF677) ApoL PF05461.11 PVD20127.1 - 6e-07 29.1 1.7 2.7e-05 23.7 1.7 2.4 1 1 0 1 1 1 1 Apolipoprotein L HD_4 PF13328.6 PVD20127.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 HD domain RTX PF02382.15 PVD20127.1 - 0.085 12.5 1.0 0.11 12.1 0.4 1.4 1 1 0 1 1 1 0 N-terminal domain in RTX protein DUF2207 PF09972.9 PVD20127.1 - 0.089 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ApoL PF05461.11 PVD20128.1 - 7e-08 32.1 8.6 1.4e-06 27.9 8.6 2.1 1 1 0 1 1 1 1 Apolipoprotein L DUF2207 PF09972.9 PVD20128.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.27 PVD20130.1 - 8.7e-29 100.6 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_2 PF08356.12 PVD20130.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 EF hand associated ApoL PF05461.11 PVD20131.1 - 0.0055 16.1 7.8 0.011 15.1 7.8 1.5 1 1 0 1 1 1 1 Apolipoprotein L WH1 PF00568.23 PVD20131.1 - 0.075 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 WH1 domain DUF4225 PF13988.6 PVD20131.1 - 0.41 10.2 3.0 10 5.6 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4225) LicD PF04991.13 PVD20132.1 - 1.5e-15 58.0 1.1 4.4e-10 40.1 0.1 2.1 2 0 0 2 2 2 2 LicD family ApoL PF05461.11 PVD20133.1 - 7.9e-05 22.1 4.4 0.00041 19.8 4.4 1.8 1 1 0 1 1 1 1 Apolipoprotein L Baculo_p74 PF04583.12 PVD20133.1 - 0.075 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Baculoviridae p74 conserved region TFCD_C PF12612.8 PVD20133.1 - 0.076 12.8 0.1 0.63 9.8 0.0 2.2 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal C-C_Bond_Lyase PF15617.6 PVD20133.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold DUF2207 PF09972.9 PVD20133.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CactinC_cactus PF09732.9 PVD20134.1 - 1.7e-42 144.3 18.0 1.5e-29 102.4 5.7 2.3 1 1 1 2 2 2 2 Cactus-binding C-terminus of cactin protein ApoL PF05461.11 PVD20135.1 - 1.3e-05 24.7 3.1 3e-05 23.5 3.1 1.7 1 1 0 1 1 1 1 Apolipoprotein L WH1 PF00568.23 PVD20135.1 - 0.02 14.8 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 WH1 domain Tic110 PF16940.5 PVD20135.1 - 4.5 5.6 5.7 0.28 9.6 0.3 1.6 2 0 0 2 2 2 0 Chloroplast envelope transporter SseC PF04888.12 PVD20135.1 - 6.8 6.2 10.8 10 5.6 10.8 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family LicD PF04991.13 PVD20136.1 - 2.8e-15 57.1 0.8 5.4e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 LicD family LicD PF04991.13 PVD20137.1 - 5e-15 56.3 2.7 5.7e-10 39.7 0.4 2.1 1 1 1 2 2 2 2 LicD family ApoL PF05461.11 PVD20138.1 - 7.9e-09 35.3 4.7 1.2e-08 34.7 4.7 1.2 1 0 0 1 1 1 1 Apolipoprotein L DUF2207 PF09972.9 PVD20138.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GHMP_kinases_C PF08544.13 PVD20138.1 - 0.15 12.4 2.0 15 6.1 0.2 3.2 2 1 1 3 3 3 0 GHMP kinases C terminal ApoL PF05461.11 PVD20139.1 - 4.3e-07 29.6 6.0 7.2e-06 25.5 6.0 2.0 1 1 0 1 1 1 1 Apolipoprotein L DUF1320 PF07030.12 PVD20139.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) MADF_DNA_bdg PF10545.9 PVD20139.1 - 0.094 13.0 0.1 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Gallidermin PF02052.15 PVD20139.1 - 0.16 12.3 1.1 0.34 11.3 1.1 1.5 1 0 0 1 1 1 0 Gallidermin DUF2207 PF09972.9 PVD20139.1 - 0.18 10.5 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ApoL PF05461.11 PVD20140.1 - 1.2e-06 28.2 4.8 1.9e-06 27.4 4.8 1.3 1 0 0 1 1 1 1 Apolipoprotein L MADF_DNA_bdg PF10545.9 PVD20140.1 - 6.5e-05 23.2 1.0 0.013 15.8 0.1 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1320 PF07030.12 PVD20140.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1320) CENP-H PF05837.12 PVD20140.1 - 0.12 12.8 1.3 0.23 11.9 0.0 2.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ApoL PF05461.11 PVD20141.1 - 0.00017 21.0 21.8 0.00072 19.0 3.6 3.0 2 2 0 2 2 2 2 Apolipoprotein L DUF2207 PF09972.9 PVD20141.1 - 0.00089 18.1 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) LicD PF04991.13 PVD20142.1 - 6.5e-14 52.6 3.2 1.4e-09 38.5 0.7 2.2 1 1 1 2 2 2 2 LicD family LicD PF04991.13 PVD20143.1 - 5.1e-10 39.9 0.1 5.8e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 LicD family LicD PF04991.13 PVD20144.1 - 2.6e-15 57.2 2.9 1.7e-09 38.1 1.2 2.2 1 1 1 2 2 2 2 LicD family LicD PF04991.13 PVD20146.1 - 5.6e-12 46.3 0.2 7.3e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 LicD family LicD PF04991.13 PVD20147.1 - 4e-14 53.3 1.4 8.8e-10 39.1 0.2 2.2 1 1 0 2 2 2 2 LicD family LicD PF04991.13 PVD20148.1 - 3.4e-14 53.5 3.3 6.3e-10 39.6 0.2 2.6 2 1 1 3 3 3 2 LicD family SYF2 PF08231.12 PVD20148.1 - 0.051 14.0 0.1 0.098 13.1 0.1 1.4 1 0 0 1 1 1 0 SYF2 splicing factor LicD PF04991.13 PVD20149.1 - 2.5e-18 67.1 0.3 3.6e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 LicD family 7tm_1 PF00001.21 PVD20150.1 - 3.3e-16 59.4 4.2 4.6e-16 58.9 4.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD20150.1 - 0.0012 18.3 0.4 0.0012 18.3 0.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD20150.1 - 0.017 14.4 3.2 0.024 13.9 3.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD20151.1 - 4.4e-07 29.5 0.0 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cytochrome_C554 PF13435.6 PVD20152.1 - 0.14 13.1 4.0 1.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c554 and c-prime PBP_sp32 PF07222.12 PVD20152.1 - 0.24 10.8 5.6 0.26 10.7 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cytomega_UL84 PF06284.11 PVD20152.1 - 0.39 9.1 6.3 0.37 9.2 6.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Neur_chan_LBD PF02931.23 PVD20153.1 - 3.8e-67 225.9 3.1 5.3e-67 225.4 3.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD20153.1 - 2.8e-47 161.8 0.4 2.8e-46 158.5 0.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LptF_LptG PF03739.14 PVD20153.1 - 0.032 13.1 2.7 0.71 8.7 1.4 2.3 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Peptidase_U4 PF03419.13 PVD20153.1 - 4 6.6 9.5 0.15 11.3 3.8 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA NAM-associated PF14303.6 PVD20154.1 - 0.0096 16.7 3.1 0.0096 16.7 3.1 1.7 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain Ribosomal_L31e PF01198.19 PVD20154.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L31e Herpes_BLLF1 PF05109.13 PVD20154.1 - 4 5.3 13.7 4.7 5.1 13.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) bZIP_1 PF00170.21 PVD20156.1 - 3.2e-05 23.9 2.2 3.2e-05 23.9 2.2 3.0 4 0 0 4 4 4 1 bZIP transcription factor Shugoshin_N PF07558.11 PVD20156.1 - 0.0044 16.9 0.1 0.26 11.2 0.0 2.7 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region M3 PF09213.10 PVD20156.1 - 0.054 12.2 0.0 0.092 11.4 0.0 1.3 1 0 0 1 1 1 0 M3 betaPIX_CC PF16523.5 PVD20156.1 - 0.92 9.4 7.6 1.9 8.4 0.4 2.9 3 0 0 3 3 3 0 betaPIX coiled coil DivIC PF04977.15 PVD20156.1 - 3.4 7.5 7.3 0.57 10.0 0.8 2.8 2 0 0 2 2 2 0 Septum formation initiator Med30 PF11315.8 PVD20156.1 - 4.3 7.5 9.6 0.75 10.0 0.8 3.5 3 0 0 3 3 3 0 Mediator complex subunit 30 Cep57_CLD_2 PF14197.6 PVD20156.1 - 9.4 6.4 14.8 2.1 8.5 1.5 4.8 5 0 0 5 5 5 0 Centrosome localisation domain of PPC89 Pkinase PF00069.25 PVD20157.1 - 1.3e-57 195.2 0.0 1.8e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20157.1 - 2.6e-34 118.7 0.0 3.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD20157.1 - 6.1e-05 22.0 0.0 7.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD20157.1 - 0.0032 16.5 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PVD20157.1 - 0.0074 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PVD20157.1 - 0.014 15.3 0.3 0.05 13.5 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD20157.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Ribosomal_L22 PF00237.19 PVD20158.1 - 3.4e-44 149.3 0.5 4.9e-44 148.8 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Zip PF02535.22 PVD20159.1 - 2.3e-64 217.8 7.6 2.7e-64 217.5 7.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.16 PVD20159.1 - 0.00047 19.2 1.1 0.00047 19.2 1.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5438 PF17506.2 PVD20159.1 - 0.039 14.3 0.2 0.039 14.3 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5438) EpsG PF14897.6 PVD20159.1 - 2.7 7.2 14.5 0.24 10.7 7.9 2.1 2 0 0 2 2 2 0 EpsG family Tti2 PF10521.9 PVD20160.1 - 7.9e-15 55.1 0.5 9.6e-14 51.6 0.1 2.3 1 1 1 2 2 2 1 Tti2 family RTP1_C1 PF10363.9 PVD20160.1 - 0.053 13.7 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cu_amine_oxidN2 PF02727.16 PVD20161.1 - 2.6e-07 30.8 0.0 5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 PVD20162.1 - 9.7e-90 301.4 0.8 1e-88 298.0 0.1 2.5 2 1 0 2 2 2 1 Copper amine oxidase, enzyme domain DUF4214 PF13946.6 PVD20162.1 - 0.03 14.4 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) GP52 PF17468.2 PVD20162.1 - 0.14 12.4 0.2 0.36 11.0 0.2 1.7 1 0 0 1 1 1 0 Phage gene product 52 PAS_11 PF14598.6 PVD20164.1 - 1.6e-29 102.3 1.1 5.6e-24 84.4 0.3 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 PVD20164.1 - 1.7e-26 92.3 0.2 9.2e-18 64.3 0.1 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 PVD20164.1 - 6.7e-18 64.7 0.1 1.2e-08 34.9 0.0 2.7 2 1 0 2 2 2 2 PAS fold HLH PF00010.26 PVD20164.1 - 4.6e-13 48.9 0.7 8.5e-13 48.1 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 PVD20164.1 - 8.8e-10 38.8 0.0 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 PVD20164.1 - 1e-06 29.0 0.0 0.024 14.9 0.0 2.6 2 1 0 2 2 2 2 PAS fold PAS_2 PF08446.11 PVD20164.1 - 0.00045 20.9 0.0 0.0017 19.0 0.0 2.0 2 0 0 2 2 2 1 PAS fold WH1 PF00568.23 PVD20165.1 - 9e-34 115.8 0.3 1.8e-33 114.8 0.3 1.5 1 0 0 1 1 1 1 WH1 domain GAS PF13851.6 PVD20165.1 - 0.00026 20.4 33.0 0.0016 17.8 13.8 3.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 PVD20165.1 - 0.0093 16.2 42.1 0.031 14.5 30.1 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) BST2 PF16716.5 PVD20165.1 - 0.032 14.8 10.2 0.032 14.8 10.2 3.8 2 1 3 5 5 5 0 Bone marrow stromal antigen 2 HOOK PF05622.12 PVD20165.1 - 0.036 12.2 29.1 0.065 11.4 29.1 1.4 1 0 0 1 1 1 0 HOOK protein SSXT PF05030.12 PVD20165.1 - 0.079 12.6 6.8 0.27 10.9 1.6 2.6 2 0 0 2 2 2 0 SSXT protein (N-terminal region) CENP-F_leu_zip PF10473.9 PVD20165.1 - 0.23 11.5 35.9 9.8 6.2 9.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZYG-11_interact PF05884.12 PVD20165.1 - 0.3 10.4 3.8 0.31 10.4 2.6 1.6 1 1 0 1 1 1 0 Interactor of ZYG-11 Cnn_1N PF07989.11 PVD20165.1 - 0.75 10.0 27.6 0.38 10.9 4.5 3.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 PVD20165.1 - 0.81 9.9 36.9 1.3 9.2 19.5 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 GvpK PF05121.12 PVD20165.1 - 2.8 8.0 15.1 0.93 9.6 2.5 3.0 2 1 1 3 3 3 0 Gas vesicle protein K YabA PF06156.13 PVD20165.1 - 3 8.5 28.5 10 6.8 8.5 4.3 1 1 3 4 4 4 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 PVD20165.1 - 3.1 8.0 36.7 0.065 13.5 10.4 4.4 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 PVD20165.1 - 4.5 4.6 33.1 8.4 3.8 33.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lipoprotein_6 PF01441.19 PVD20165.1 - 4.9 7.1 13.3 0.42 10.6 0.7 2.7 2 1 2 4 4 4 0 Lipoprotein HsbA PF12296.8 PVD20165.1 - 8 6.9 9.1 38 4.7 0.3 3.9 3 1 1 4 4 4 0 Hydrophobic surface binding protein A UCH PF00443.29 PVD20166.1 - 7.2e-41 140.4 0.1 1.3e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PVD20166.1 - 3.1e-17 62.7 11.0 3.1e-17 62.7 11.0 2.3 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PVD20166.1 - 1.8e-09 37.6 4.0 1.4e-06 28.2 0.0 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase TPR_1 PF00515.28 PVD20167.1 - 7.5e-16 57.2 0.1 3.2e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD20167.1 - 1.1e-13 50.6 0.1 9.3e-05 22.0 0.0 3.7 2 1 1 3 3 3 3 TPR repeat FKBP_C PF00254.28 PVD20167.1 - 1.3e-12 47.9 0.0 3.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 PVD20167.1 - 1.7e-11 43.4 0.8 5.3e-08 32.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20167.1 - 5.2e-11 41.8 0.1 8.8e-06 25.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD20167.1 - 2.4e-08 34.4 0.0 1.1e-07 32.2 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD20167.1 - 5.9e-08 32.9 0.0 1.1e-05 25.8 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD20167.1 - 1.3e-06 28.7 0.1 7.2e-05 23.2 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD20167.1 - 7.3e-06 26.5 0.3 0.00034 21.2 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD20167.1 - 1.6e-05 24.3 0.9 6e-05 22.4 0.9 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD20167.1 - 2.3e-05 24.1 0.0 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD20167.1 - 5.5e-05 23.3 0.1 0.011 16.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD20167.1 - 9.3e-05 22.6 0.0 0.00069 19.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 PVD20167.1 - 0.00026 21.1 0.0 0.0011 19.1 0.0 2.1 1 0 0 1 1 1 1 BDBT FKBP like N-terminal TPR_10 PF13374.6 PVD20167.1 - 0.002 17.9 0.2 0.23 11.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 PVD20167.1 - 0.01 16.2 0.1 0.039 14.3 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 PVD20167.1 - 0.01 16.3 0.0 0.031 14.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 PVD20167.1 - 0.02 15.1 0.1 0.058 13.6 0.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PVD20167.1 - 0.031 14.4 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 PVD20167.1 - 0.72 8.7 7.3 0.11 11.4 0.7 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RRM_1 PF00076.22 PVD20168.1 - 1.3e-15 56.9 0.2 1.9e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Binary_toxB_2 PF17475.2 PVD20168.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 2 DUF2039 PF10217.9 PVD20169.1 - 3.4e-29 101.0 18.5 6.2e-29 100.2 18.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 PVD20169.1 - 0.021 15.4 19.0 0.055 14.1 17.5 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Cytochrome_C7 PF14522.6 PVD20169.1 - 0.97 9.5 13.5 5.5 7.1 10.8 2.8 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 PVD20169.1 - 1.6 8.8 14.1 26 4.9 14.1 2.3 1 1 0 1 1 1 0 zinc-ribbons zf-HC5HC2H_2 PF13832.6 PVD20169.1 - 1.8 8.8 12.9 6 7.1 7.8 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 PVD20169.1 - 4.8 7.3 12.4 96 3.1 12.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon Tim44 PF04280.15 PVD20170.1 - 8.2e-21 74.7 1.0 2.5e-17 63.4 0.0 3.1 2 1 1 3 3 3 2 Tim44-like domain DUF1241 PF06840.11 PVD20170.1 - 0.036 13.7 1.9 0.08 12.6 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) BDV_P24 PF06595.11 PVD20170.1 - 0.044 13.7 1.3 0.12 12.2 0.6 2.0 3 0 0 3 3 2 0 Borna disease virus P24 protein Exonuc_VII_L PF02601.15 PVD20170.1 - 0.048 13.2 5.2 0.076 12.6 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GlutR_dimer PF00745.20 PVD20170.1 - 0.052 14.0 5.5 0.14 12.6 5.5 1.8 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain T3SSipB PF16535.5 PVD20170.1 - 0.071 13.6 6.9 0.18 12.3 6.9 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1640 PF07798.11 PVD20170.1 - 0.097 12.7 13.6 0.35 10.9 10.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Uso1_p115_C PF04871.13 PVD20170.1 - 0.25 11.7 19.8 0.14 12.5 14.7 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF501 PF04417.12 PVD20170.1 - 0.41 10.4 2.3 0.76 9.6 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Atg14 PF10186.9 PVD20170.1 - 0.73 8.9 8.2 1 8.4 8.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3347 PF11827.8 PVD20170.1 - 0.83 9.8 11.8 1.8 8.7 5.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Uteroglobin PF01099.17 PVD20170.1 - 1 9.8 4.8 0.83 10.0 1.3 2.5 3 0 0 3 3 2 0 Uteroglobin family APG6_N PF17675.1 PVD20170.1 - 1.4 9.4 13.8 2.5 8.6 13.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 PVD20170.1 - 1.6 8.8 11.5 3.1 7.9 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4446 PF14584.6 PVD20170.1 - 2.5 8.1 7.3 3.4 7.7 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4407 PF14362.6 PVD20170.1 - 2.7 7.3 11.2 4 6.7 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Halogen_Hydrol PF10112.9 PVD20170.1 - 3.8 7.5 8.6 17 5.4 3.5 2.4 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DivIVA PF05103.13 PVD20170.1 - 4.2 7.5 17.3 3.2 7.8 4.9 2.4 1 1 1 2 2 2 0 DivIVA protein DUF1664 PF07889.12 PVD20170.1 - 4.3 7.4 8.3 72 3.4 8.3 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 PVD20170.1 - 6.2 7.1 9.5 2.2 8.6 0.7 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Cytochrom_C_2 PF01322.20 PVD20170.1 - 6.9 7.6 8.5 1.4 9.8 2.6 2.5 2 1 0 2 2 2 0 Cytochrome C' zinc-ribbon_6 PF10005.9 PVD20171.1 - 0.065 13.9 0.0 0.08 13.6 0.0 1.2 1 0 0 1 1 1 0 zinc-ribbon domain DEAD PF00270.29 PVD20172.1 - 2.4e-47 161.0 0.0 7.3e-47 159.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD20172.1 - 3.9e-28 98.0 0.0 1.9e-26 92.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD20172.1 - 3.9e-08 33.5 0.2 1.2e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PVD20172.1 - 0.00094 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 PVD20172.1 - 0.037 14.3 0.9 0.73 10.1 0.8 3.0 1 1 0 2 2 2 0 AAA domain Myosin_head PF00063.21 PVD20173.1 - 1.3e-241 803.6 0.4 1.6e-241 803.2 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PVD20173.1 - 1.7e-51 174.6 0.5 3e-51 173.7 0.5 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 PVD20173.1 - 6.1e-06 25.7 0.1 1.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD20173.1 - 0.0014 18.4 0.1 0.0033 17.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD20173.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain AAA_16 PF13191.6 PVD20173.1 - 0.051 14.0 0.3 0.41 11.0 0.0 2.6 4 0 0 4 4 4 0 AAA ATPase domain Hpr_kinase_C PF07475.12 PVD20173.1 - 0.065 12.8 0.7 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 PVD20173.1 - 0.073 13.3 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PVD20173.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 PVD20173.1 - 0.11 13.0 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IQ PF00612.27 PVD20173.1 - 3.8 7.6 5.0 3.4 7.7 2.5 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif GalP_UDP_transf PF01087.22 PVD20175.1 - 6.8e-66 222.2 0.0 1.3e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 PVD20175.1 - 3.1e-19 69.3 1.4 8e-19 68.0 0.5 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 PVD20175.1 - 0.00046 20.9 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 PVD20175.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) LRR_9 PF14580.6 PVD20176.1 - 1.1e-29 103.2 10.8 3.2e-19 69.1 1.9 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 PVD20176.1 - 3.9e-16 58.9 25.3 7.9e-06 26.1 2.7 6.2 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20176.1 - 7.4e-12 44.9 29.9 6.6e-05 22.6 0.8 6.1 4 2 3 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 PVD20176.1 - 0.55 10.4 7.4 34 4.8 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeat Peptidase_C15 PF01470.17 PVD20177.1 - 9.9e-18 65.0 0.0 1.2e-17 64.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 PVD20177.1 - 2.7e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 PhoLip_ATPase_C PF16212.5 PVD20178.1 - 1.1e-50 172.7 42.2 2.4e-41 142.1 13.5 3.3 2 1 1 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 PVD20178.1 - 2.2e-11 43.7 0.0 1.8e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PVD20178.1 - 1.1e-05 25.1 0.2 1.1e-05 25.1 0.2 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PVD20178.1 - 0.0021 18.4 0.1 0.074 13.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4293 PF14126.6 PVD20178.1 - 5 7.4 9.0 0.44 10.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) UQ_con PF00179.26 PVD20179.1 - 0.00023 20.8 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3839 PF12943.7 PVD20179.1 - 0.0087 15.5 0.2 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Mis14 PF08641.12 PVD20179.1 - 0.18 12.1 4.7 0.22 11.8 3.7 1.6 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Golgin_A5 PF09787.9 PVD20180.1 - 0.00032 20.3 2.4 0.0004 20.0 2.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 GAS PF13851.6 PVD20180.1 - 0.0014 18.0 6.7 0.0022 17.4 6.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 PVD20180.1 - 0.029 14.1 3.1 0.044 13.5 3.1 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2407_C PF13373.6 PVD20180.1 - 0.11 12.7 0.4 0.17 12.0 0.4 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain NDUFB10 PF10249.9 PVD20180.1 - 0.19 12.2 1.9 0.27 11.7 1.6 1.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 DNA_repr_REX1B PF14966.6 PVD20180.1 - 0.25 12.0 6.4 0.41 11.3 4.4 2.2 1 1 1 2 2 2 0 DNA repair REX1-B Filament PF00038.21 PVD20181.1 - 0.0013 18.3 58.7 0.0084 15.7 10.5 4.8 4 1 1 5 5 5 2 Intermediate filament protein BST2 PF16716.5 PVD20181.1 - 0.0044 17.6 2.8 0.0044 17.6 2.8 8.0 5 3 2 8 8 8 1 Bone marrow stromal antigen 2 DUF4404 PF14357.6 PVD20181.1 - 0.033 14.8 0.6 0.033 14.8 0.6 6.7 6 2 0 7 7 7 0 Domain of unknown function (DUF4404) MAD PF05557.13 PVD20181.1 - 0.16 10.3 58.3 0.0057 15.1 13.6 3.4 3 0 0 3 3 3 0 Mitotic checkpoint protein DUF3584 PF12128.8 PVD20181.1 - 0.19 9.2 58.4 0.019 12.5 15.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 PVD20181.1 - 0.86 10.0 62.1 0.033 14.7 8.8 4.8 3 2 2 5 5 5 0 Fez1 YkuI_C PF10388.9 PVD20181.1 - 5 6.9 21.3 0.042 13.7 2.5 4.0 3 2 0 3 3 3 0 EAL-domain associated signalling protein domain CoA_transf_3 PF02515.17 PVD20182.1 - 2.5e-63 214.5 0.1 9.4e-63 212.5 0.0 1.9 1 1 1 2 2 2 1 CoA-transferase family III SNF2_N PF00176.23 PVD20183.1 - 1.9e-65 220.9 0.3 9.9e-65 218.5 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 PVD20183.1 - 5.8e-35 119.8 0.3 5.8e-35 119.8 0.3 5.0 4 0 0 4 4 4 1 CDH1/2 SANT-Helical linker 1 DUF4208 PF13907.6 PVD20183.1 - 1.3e-22 80.0 0.5 1.3e-22 80.0 0.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 PVD20183.1 - 4.7e-20 72.0 0.0 1.2e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PVD20183.1 - 6.5e-20 70.8 8.8 1.6e-10 40.7 0.0 4.3 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PVD20183.1 - 4.1e-10 39.9 1.1 5.3e-09 36.3 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Spectrin PF00435.21 PVD20184.1 - 2.3e-19 69.8 7.2 5.5e-09 36.5 1.7 3.1 1 1 2 3 3 3 3 Spectrin repeat BRCT_assoc PF12820.7 PVD20184.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Serine-rich domain associated with BRCT Jnk-SapK_ap_N PF09744.9 PVD20184.1 - 0.1 12.8 0.3 0.1 12.8 0.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3958 PF13125.6 PVD20184.1 - 0.21 11.8 4.7 0.21 11.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Rx_N PF18052.1 PVD20184.1 - 2.1 8.7 6.6 1.9 8.8 1.4 2.9 3 1 0 3 3 3 0 Rx N-terminal domain NADH-G_4Fe-4S_3 PF10588.9 PVD20187.1 - 0.00016 21.2 0.4 0.00031 20.2 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Whib PF02467.16 PVD20187.1 - 0.0093 16.5 0.2 0.0093 16.5 0.2 1.8 2 1 0 2 2 2 1 Transcription factor WhiB RGM_C PF06534.13 PVD20189.1 - 1.5e-53 180.9 0.1 1.8e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus KH_1 PF00013.29 PVD20196.1 - 4.4e-05 23.2 0.0 0.042 13.7 0.0 3.3 3 0 0 3 3 3 3 KH domain LicD PF04991.13 PVD20197.1 - 3.3e-14 53.6 0.8 8.1e-14 52.3 0.0 2.1 3 1 0 3 3 3 1 LicD family SH2 PF00017.24 PVD20199.1 - 2.2e-13 50.1 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DUF2781 PF10914.8 PVD20200.1 - 2e-11 44.5 6.5 2e-11 44.5 6.5 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF2781) DUF2781 PF10914.8 PVD20201.1 - 1e-12 48.7 2.3 1e-12 48.7 2.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) LigB PF02900.18 PVD20202.1 - 3.5e-10 39.4 0.0 4.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 PVD20203.1 - 4.1e-30 104.9 26.6 5.4e-30 104.5 26.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD20203.1 - 6.6e-19 68.1 26.4 4.2e-18 65.5 26.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Aldedh PF00171.22 PVD20204.1 - 1.3e-75 254.7 0.6 5.1e-44 150.6 0.2 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family OmdA PF13376.6 PVD20204.1 - 0.099 12.7 0.9 0.19 11.8 0.9 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated YtxH PF12732.7 PVD20206.1 - 6.3 7.4 7.5 8.9 6.9 1.4 3.2 3 0 0 3 3 3 0 YtxH-like protein Pkinase PF00069.25 PVD20207.1 - 5.1e-73 245.7 0.0 6.2e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20207.1 - 4.3e-32 111.4 0.0 9e-32 110.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD20207.1 - 2e-07 30.6 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD20207.1 - 0.00025 20.0 0.0 0.00045 19.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD20207.1 - 0.0024 17.8 0.0 0.0082 16.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD20207.1 - 0.0034 16.8 0.1 0.0079 15.6 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PVD20207.1 - 0.0093 15.6 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PHD PF00628.29 PVD20208.1 - 5e-07 29.5 1.7 1.1e-06 28.4 1.7 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 PVD20208.1 - 0.039 13.9 0.9 0.063 13.2 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 PVD20208.1 - 0.043 14.1 0.5 0.11 12.9 0.5 1.7 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.6 PVD20208.1 - 0.19 12.1 3.1 0.36 11.2 3.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-PHD-like PF15446.6 PVD20208.1 - 1.9 8.1 5.2 0.31 10.6 1.4 1.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_11 PF17123.5 PVD20208.1 - 4.2 7.2 6.6 8.1 6.3 6.6 1.4 1 0 0 1 1 1 0 RING-like zinc finger TTL PF03133.15 PVD20209.1 - 3.4e-78 262.8 0.1 5.1e-78 262.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD20209.1 - 1.4e-06 27.8 0.0 0.0021 17.3 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD20209.1 - 1.1e-05 24.9 0.0 0.028 13.7 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 PVD20209.1 - 0.0037 17.3 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain PAS PF00989.25 PVD20217.1 - 6.7e-09 35.8 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 PVD20217.1 - 8e-06 26.1 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 PVD20217.1 - 4.7e-05 23.6 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 PVD20217.1 - 0.00017 21.5 0.0 0.00054 19.9 0.0 1.8 2 0 0 2 2 2 1 PAS domain GP68 PF17469.2 PVD20217.1 - 0.1 13.0 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 Phage protein Gp68 PAS_7 PF12860.7 PVD20217.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold PDEase_I PF00233.19 PVD20218.1 - 4.6e-80 268.8 4.0 6.6e-80 268.3 4.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase mRNA_cap_enzyme PF01331.19 PVD20219.1 - 0.023 14.5 0.1 5.3 6.8 0.2 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Spaetzle PF16077.5 PVD20220.1 - 3.6e-08 33.8 0.2 4.5e-08 33.5 0.2 1.1 1 0 0 1 1 1 1 Spaetzle NGF PF00243.18 PVD20220.1 - 0.00022 21.5 0.1 0.00035 20.8 0.1 1.3 1 0 0 1 1 1 1 Nerve growth factor family EGF_CA PF07645.15 PVD20223.1 - 0 1033.0 709.7 2.6e-10 40.3 6.3 47.4 45 2 2 47 47 47 43 Calcium-binding EGF domain cEGF PF12662.7 PVD20223.1 - 3.4e-223 720.7 412.4 2.6e-08 33.6 1.9 49.5 48 1 0 48 48 48 43 Complement Clr-like EGF-like EGF PF00008.27 PVD20223.1 - 1e-90 297.5 686.5 7e-05 23.1 7.9 49.9 48 1 1 49 49 49 43 EGF-like domain TB PF00683.17 PVD20223.1 - 5.8e-88 288.4 148.6 2e-12 46.7 2.6 11.7 10 0 0 10 10 10 9 TB domain hEGF PF12661.7 PVD20223.1 - 2.7e-85 278.4 675.7 0.00018 22.0 5.3 52.5 50 1 1 51 51 51 42 Human growth factor-like EGF FXa_inhibition PF14670.6 PVD20223.1 - 3.5e-78 257.6 724.3 3.4e-10 40.0 9.5 48.8 45 5 4 49 49 49 37 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PVD20223.1 - 6.7e-53 176.6 587.3 1.3e-08 34.9 12.9 47.6 45 1 1 46 46 46 36 EGF domain Plasmod_Pvs28 PF06247.11 PVD20223.1 - 3e-18 65.8 489.0 0.0014 18.9 6.4 44.5 43 1 1 44 44 44 28 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 PVD20223.1 - 0.0046 17.0 7.3 0.0046 17.0 7.3 44.4 46 1 1 47 47 47 18 MSP1 EGF domain 1 Cu2_monoox_C PF03712.15 PVD20224.1 - 1.2e-71 239.4 0.1 7.2e-35 119.8 0.0 2.6 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD20224.1 - 3.3e-33 114.7 2.1 8.8e-20 71.3 0.1 2.6 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 PVD20224.1 - 3.6e-09 36.2 3.5 0.002 18.1 0.0 3.6 3 0 0 3 3 3 2 NHL repeat SBBP PF06739.11 PVD20224.1 - 3.3e-05 23.8 2.3 1.9 8.5 0.0 4.0 4 0 0 4 4 4 2 Beta-propeller repeat SGL PF08450.12 PVD20224.1 - 0.016 14.8 0.1 3.3 7.2 0.0 3.2 2 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PVD20224.1 - 0.026 14.7 0.0 33 5.2 0.0 3.9 3 0 0 3 3 3 0 Two component regulator propeller HCV_NS5a_1a PF08300.13 PVD20224.1 - 0.032 14.3 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain TMEM154 PF15102.6 PVD20224.1 - 0.043 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.12 PVD20224.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ODV-E18 PF10717.9 PVD20224.1 - 0.12 12.2 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 7tm_1 PF00001.21 PVD20225.1 - 3.4e-17 62.7 12.6 6.1e-17 61.8 12.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1397 PF07165.11 PVD20226.1 - 0.028 13.9 3.2 1.4 8.3 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1397) YfmQ PF10787.9 PVD20228.1 - 1.6 8.5 6.2 30 4.4 0.5 3.5 1 1 2 3 3 3 0 Uncharacterised protein from bacillus cereus group DUF3456 PF11938.8 PVD20229.1 - 8.9e-30 104.3 2.3 2e-29 103.1 2.3 1.5 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.17 PVD20229.1 - 0.024 14.7 0.4 0.088 12.9 0.1 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 RT_RNaseH_2 PF17919.1 PVD20230.1 - 0.00078 19.4 0.1 0.0019 18.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EH_Signature PF15611.6 PVD20230.1 - 0.028 13.9 0.5 0.051 13.0 0.5 1.4 1 1 0 1 1 1 0 EH_Signature domain zf-CCHC PF00098.23 PVD20231.1 - 3e-05 23.9 0.9 5.4e-05 23.1 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4806 PF16064.5 PVD20231.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) zf-CCHC_3 PF13917.6 PVD20231.1 - 0.11 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M24 PF00557.24 PVD20232.1 - 1.6e-53 181.5 0.0 1.9e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 C2 PF00168.30 PVD20233.1 - 9.9e-09 35.4 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain DSL PF01414.19 PVD20234.1 - 0.68 10.3 4.9 1.4 9.3 4.9 1.5 1 0 0 1 1 1 0 Delta serrate ligand Ank_5 PF13857.6 PVD20235.1 - 8.7e-16 57.8 1.0 1.3e-08 35.0 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD20235.1 - 3.5e-14 52.9 0.2 9.5e-06 26.1 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20235.1 - 2.1e-13 50.7 0.1 5.5e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD20235.1 - 4.5e-11 41.9 0.3 8.2e-05 22.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PVD20235.1 - 2.5e-10 40.3 0.5 0.00081 19.7 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Endonuc-HincII PF09226.11 PVD20235.1 - 0.057 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease HincII Nrap_D3 PF17404.2 PVD20236.1 - 1.7e-39 135.4 0.0 3.8e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 PVD20236.1 - 2.7e-39 134.8 0.0 9e-39 133.0 0.0 1.9 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 PVD20236.1 - 3.4e-31 108.4 0.0 6.2e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 PVD20236.1 - 9e-31 106.9 0.0 2.5e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap_D5 PF17406.2 PVD20236.1 - 1.2e-19 70.6 0.6 1.5e-16 60.6 0.1 2.5 1 1 1 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 PVD20236.1 - 3.7e-14 52.8 1.1 4.1e-13 49.4 1.2 2.3 1 1 0 1 1 1 1 Nrap protein PAP/OAS-like domain Arrestin_C PF02752.22 PVD20238.1 - 1.3e-13 51.6 0.0 8.1e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD20238.1 - 7.2e-10 39.1 0.0 4.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain F-box-like PF12937.7 PVD20239.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD20239.1 - 0.0013 18.5 0.0 0.0047 16.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain DIRP PF06584.13 PVD20239.1 - 0.07 13.3 0.3 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 DIRP GST_C_6 PF17171.4 PVD20240.1 - 5e-12 45.4 0.7 1.4e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sec_GG PF07549.14 PVD20240.1 - 0.6 9.7 6.8 24 4.6 0.2 5.1 3 0 0 3 3 3 0 SecD/SecF GG Motif ADP_PFK_GK PF04587.15 PVD20241.1 - 1.9e-117 392.5 0.0 2.1e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region CPDase PF07823.11 PVD20241.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein HA2 PF04408.23 PVD20242.1 - 2.9e-15 56.5 0.1 2.9e-15 56.5 0.1 3.6 2 2 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PVD20242.1 - 4.2e-13 49.6 0.0 1.3e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PVD20242.1 - 2.3e-10 40.7 0.0 5.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 PVD20242.1 - 5e-07 29.7 1.7 2.6e-06 27.3 1.7 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD20242.1 - 0.00059 20.1 0.2 0.00059 20.1 0.2 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PVD20242.1 - 0.0042 17.4 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PVD20242.1 - 0.0084 16.0 1.9 0.021 14.8 0.6 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 PVD20242.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 PVD20242.1 - 0.11 12.5 3.6 0.12 12.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Ogr_Delta PF04606.12 PVD20242.1 - 0.12 12.4 1.5 0.31 11.0 1.5 1.8 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger ATPase PF06745.13 PVD20242.1 - 0.13 11.6 0.7 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 PVD20242.1 - 0.47 11.0 0.0 0.47 11.0 0.0 2.8 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 PVD20242.1 - 2.6 8.4 7.1 0.36 11.2 0.1 2.9 4 0 0 4 4 4 0 AAA ATPase domain Bac_DnaA PF00308.18 PVD20243.1 - 0.027 14.3 9.8 0.018 14.9 6.7 2.0 1 1 1 2 2 2 0 Bacterial dnaA protein ALMT PF11744.8 PVD20243.1 - 0.58 8.9 11.0 0.079 11.8 7.0 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter V-set_2 PF15910.5 PVD20243.1 - 7.7 6.6 8.7 2.7 8.1 0.6 2.9 3 0 0 3 3 3 0 ICOS V-set domain PAW PF04721.17 PVD20244.1 - 2.8e-63 213.3 0.0 4.4e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 PVD20244.1 - 1e-17 63.8 0.0 2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 PVD20244.1 - 1.1e-13 51.6 2.9 1.4e-13 51.3 1.4 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 PVD20244.1 - 3.5e-12 46.2 1.6 8.6e-12 45.0 1.6 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Arm-DNA-bind_2 PF12167.8 PVD20245.1 - 0.0031 17.4 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain BLOC1_2 PF10046.9 PVD20245.1 - 0.032 14.5 4.1 0.048 14.0 0.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4709 PF15821.5 PVD20245.1 - 0.037 14.3 0.9 0.037 14.3 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) HMG_box PF00505.19 PVD20245.1 - 0.041 14.3 0.3 0.12 12.8 0.3 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Pox_F11 PF04943.12 PVD20245.1 - 0.07 12.2 2.8 0.084 11.9 2.8 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Peptidase_C93 PF06035.11 PVD20245.1 - 0.13 12.0 1.4 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP DUF4200 PF13863.6 PVD20245.1 - 0.55 10.7 23.0 31 5.0 5.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CPG4 PF15481.6 PVD20245.1 - 1.1 9.9 6.5 2 9.1 0.4 2.6 2 1 1 3 3 3 0 Chondroitin proteoglycan 4 DUF4375 PF14300.6 PVD20245.1 - 6.8 7.0 10.5 1.2 9.4 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) MCU PF04678.13 PVD20245.1 - 8.9 6.4 9.9 1.2e+02 2.7 9.9 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Phosphodiest PF01663.22 PVD20247.1 - 5.3e-10 39.4 0.1 1.1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD20247.1 - 1.6e-08 34.4 0.3 6.7e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 PVD20247.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Endosulfine PF04667.17 PVD20248.1 - 1.3e-08 34.9 0.9 2.2e-08 34.1 0.8 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1818 PF08848.11 PVD20249.1 - 0.012 15.7 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) DUF2781 PF10914.8 PVD20250.1 - 4e-15 56.5 5.5 4e-15 56.5 5.5 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2781) ABC2_membrane_3 PF12698.7 PVD20250.1 - 0.74 8.9 12.0 2.1 7.4 6.3 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein RVT_1 PF00078.27 PVD20251.1 - 5.6e-29 101.2 0.0 1.2e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PVD20251.1 - 0.00018 21.3 0.1 0.00054 19.8 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PfkB PF00294.24 PVD20253.1 - 3.8e-58 197.2 0.0 4.9e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ribosomal_L24 PF17136.4 PVD20254.1 - 4.1e-12 46.3 0.0 7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 AHSA1 PF08327.11 PVD20254.1 - 0.0052 17.0 0.1 0.0069 16.6 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DBP10CT PF08147.12 PVD20254.1 - 0.2 11.9 2.2 14 6.1 0.0 2.2 2 0 0 2 2 2 0 DBP10CT (NUC160) domain G-patch PF01585.23 PVD20255.1 - 1e-13 50.9 2.7 2.1e-13 49.9 2.7 1.5 1 0 0 1 1 1 1 G-patch domain Surp PF01805.20 PVD20255.1 - 4.3e-10 39.4 2.0 5.5e-10 39.1 0.0 2.3 3 0 0 3 3 3 1 Surp module G-patch_2 PF12656.7 PVD20255.1 - 0.0016 18.5 0.2 0.0042 17.1 0.2 1.8 1 0 0 1 1 1 1 G-patch domain DUF4142 PF13628.6 PVD20255.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) LIN52 PF10044.9 PVD20255.1 - 0.06 14.1 0.3 0.96 10.2 0.1 2.6 2 0 0 2 2 2 0 Retinal tissue protein SMN PF06003.12 PVD20256.1 - 1.5e-57 194.8 17.4 1.1e-56 192.1 17.4 1.9 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 PVD20256.1 - 7.2e-05 22.8 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 Tudor domain Bac_rhamnosid6H PF17389.2 PVD20256.1 - 0.029 13.7 0.2 0.041 13.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain XPG_I PF00867.18 PVD20257.1 - 1.6e-21 76.5 0.1 4.2e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PVD20257.1 - 6.4e-11 42.6 0.0 1.4e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Chromo_2 PF18704.1 PVD20257.1 - 2.6e-08 34.0 0.1 6.5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 ECM11 PF15463.6 PVD20257.1 - 0.021 15.4 0.1 0.059 13.9 0.1 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 5_3_exonuc PF01367.20 PVD20257.1 - 0.18 12.4 0.0 0.46 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold LicD PF04991.13 PVD20258.1 - 4.8e-10 39.9 0.1 4.8e-10 39.9 0.1 1.8 2 0 0 2 2 2 1 LicD family MBD_C PF14048.6 PVD20259.1 - 5.6e-31 107.1 1.6 1.1e-30 106.2 1.6 1.4 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 PVD20259.1 - 1.7e-29 101.8 0.5 4e-29 100.6 0.5 1.6 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 PVD20259.1 - 1.3e-26 92.1 0.1 7.5e-18 64.0 0.0 2.2 1 1 0 2 2 2 2 Methyl-CpG binding domain UQ_con PF00179.26 PVD20260.1 - 3e-47 159.8 0.2 4e-47 159.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PVD20260.1 - 0.016 14.9 0.0 0.054 13.2 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B CRAL_TRIO PF00650.20 PVD20261.1 - 1.1e-13 51.2 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PVD20261.1 - 0.00018 21.7 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5625 PF18539.1 PVD20261.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5625) RVT_1 PF00078.27 PVD20262.1 - 1.7e-45 155.2 0.0 1.2e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PVD20262.1 - 6.2e-11 42.2 0.0 2.1e-09 37.3 0.0 2.7 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Il13Ra_Ig PF18001.1 PVD20262.1 - 0.015 15.4 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain CBM_14 PF01607.24 PVD20263.1 - 2.1e-42 143.0 61.0 6.7e-09 35.8 5.8 7.7 7 1 0 7 7 7 7 Chitin binding Peritrophin-A domain Noelin-1 PF12308.8 PVD20264.1 - 0.064 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein Myosin_head PF00063.21 PVD20265.1 - 2.5e-148 495.3 0.0 1e-121 407.4 0.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) Chitin_synth_2 PF03142.15 PVD20265.1 - 1.6e-15 56.8 0.9 2e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD20265.1 - 4.3e-07 30.0 0.1 4.3e-07 30.0 0.1 3.1 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD20265.1 - 0.00073 19.5 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 IQ PF00612.27 PVD20265.1 - 0.00087 18.9 0.4 0.0027 17.4 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_30 PF13604.6 PVD20265.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD20265.1 - 0.013 15.9 0.0 0.047 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 PVD20265.1 - 0.017 15.4 0.0 0.059 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.6 PVD20265.1 - 0.073 12.5 0.0 0.29 10.6 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF5366 PF17328.2 PVD20265.1 - 9.6 6.3 7.6 0.8 9.8 1.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5366) LacY_symp PF01306.19 PVD20266.1 - 0.085 11.6 1.6 0.11 11.2 1.6 1.3 1 0 0 1 1 1 0 LacY proton/sugar symporter CDC13_N PF16853.5 PVD20266.1 - 0.27 10.7 4.9 0.44 10.0 0.2 2.5 1 1 0 2 2 2 0 Cell division control protein 13 N-terminus Y_phosphatase PF00102.27 PVD20267.1 - 1.4e-78 263.7 0.5 2.5e-78 262.9 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 PVD20267.1 - 3.9e-21 75.4 0.0 6.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PVD20267.1 - 2.2e-09 37.6 0.1 4.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RVT_1 PF00078.27 PVD20267.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.20 PVD20267.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PVD20267.1 - 0.012 15.7 0.3 0.057 13.5 0.0 2.3 3 0 0 3 3 3 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD20267.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2457 PF10446.9 PVD20268.1 - 1.5 7.9 10.8 1.7 7.7 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 PVD20268.1 - 2.2 7.5 11.3 2.4 7.4 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein MBDa PF16564.5 PVD20269.1 - 2.9e-25 88.2 0.8 5e-25 87.5 0.8 1.4 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 PVD20269.1 - 4.2e-24 84.0 0.1 6.2e-18 64.3 0.0 2.2 1 1 1 2 2 2 2 Methyl-CpG binding domain MBD_C PF14048.6 PVD20269.1 - 1.6e-07 31.9 2.5 1.8e-07 31.8 0.3 2.1 2 1 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 LicD PF04991.13 PVD20270.1 - 1.9e-10 41.3 0.1 3.1e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 LicD family HEPN PF05168.14 PVD20271.1 - 0.00032 20.8 0.1 0.001 19.2 0.1 1.8 1 0 0 1 1 1 1 HEPN domain DnaJ PF00226.31 PVD20271.1 - 0.0084 16.2 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain HATPase_c_3 PF13589.6 PVD20271.1 - 0.043 13.6 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SLED PF12140.8 PVD20271.1 - 0.071 13.6 0.0 0.35 11.4 0.0 2.2 1 0 0 1 1 1 0 SLED domain DUF547 PF04784.14 PVD20272.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF547 HATPase_c_3 PF13589.6 PVD20273.1 - 0.029 14.2 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN PF05168.14 PVD20274.1 - 1.5e-16 60.6 0.6 3.6e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 HEPN domain DUF4895 PF16236.5 PVD20276.1 - 0.001 18.9 0.1 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4895) HATPase_c_3 PF13589.6 PVD20276.1 - 0.0086 15.9 0.0 0.088 12.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Npa1 PF11707.8 PVD20276.1 - 0.048 13.0 0.3 0.086 12.2 0.3 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal CEP44 PF15007.6 PVD20276.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 HATPase_c_3 PF13589.6 PVD20277.1 - 4.6e-05 23.3 0.6 2.5 7.9 0.3 4.2 3 1 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN PF05168.14 PVD20278.1 - 3.2e-13 49.8 0.0 1.2e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 HEPN domain HATPase_c_3 PF13589.6 PVD20278.1 - 0.00037 20.3 4.2 5.7 6.8 0.2 5.2 4 2 0 4 4 4 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1296 PF06972.11 PVD20278.1 - 0.039 14.1 0.3 0.19 11.9 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Abhydrolase_8 PF06259.12 PVD20278.1 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Ig_3 PF13927.6 PVD20279.1 - 1.5e-31 108.8 0.3 2.2e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD20279.1 - 8.7e-24 83.4 0.6 2.1e-10 40.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD20279.1 - 7.6e-23 80.5 0.4 5.2e-08 33.0 0.5 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD20279.1 - 7.8e-19 67.8 0.3 3.2e-06 27.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD20279.1 - 8.7e-13 48.4 3.1 0.0013 18.9 0.1 4.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD20279.1 - 5.4e-09 35.5 0.0 0.0047 16.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 PVD20279.1 - 1e-05 25.9 5.2 0.65 10.4 0.3 4.9 3 3 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD20279.1 - 2.6e-05 24.2 0.2 3.4 7.8 0.0 3.9 3 2 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD20279.1 - 0.00016 21.9 3.5 1.5 9.2 0.3 5.0 3 3 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD20279.1 - 0.00038 20.4 0.1 0.58 10.3 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD20279.1 - 0.0024 18.2 0.5 9.6 6.7 0.2 3.3 3 0 0 3 3 3 1 Immunoglobulin C1-set domain I-set PF07679.16 PVD20280.1 - 2.4e-21 75.6 0.0 6.1e-15 55.1 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD20280.1 - 2.3e-20 73.0 0.0 3e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD20280.1 - 1.5e-14 53.9 3.0 5.6e-08 32.9 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD20280.1 - 5.8e-14 52.2 1.0 6.6e-10 39.2 0.0 2.5 2 1 1 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD20280.1 - 8e-10 38.9 1.6 0.00017 21.7 0.0 3.6 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD20280.1 - 2.5e-05 24.4 1.4 0.031 14.6 0.4 3.8 2 2 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD20280.1 - 9.2e-05 21.9 0.1 0.051 13.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD20280.1 - 0.0093 16.0 0.0 0.17 12.0 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Wzy_C PF04932.15 PVD20280.1 - 0.11 12.1 0.0 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 O-Antigen ligase PDCD2_C PF04194.13 PVD20280.1 - 0.26 11.4 3.0 5.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain Ig_3 PF13927.6 PVD20281.1 - 7.7e-53 177.0 8.7 1.6e-13 51.0 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 PVD20281.1 - 5.3e-51 170.6 5.1 6.7e-14 51.7 0.0 5.3 4 1 1 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD20281.1 - 5.8e-33 113.1 11.7 9.7e-08 32.2 0.0 5.9 4 2 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 PVD20281.1 - 1.8e-30 104.9 12.5 2.1e-08 34.2 0.1 5.4 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 PVD20281.1 - 1.1e-17 64.1 15.3 0.00049 20.2 0.1 7.8 5 4 0 5 5 5 4 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD20281.1 - 1.9e-13 50.5 10.1 0.025 14.8 0.6 8.8 5 5 1 6 6 6 4 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD20281.1 - 2.3e-13 50.0 0.6 0.0012 18.8 0.1 4.7 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD20281.1 - 2e-12 47.4 10.7 0.52 10.7 0.6 7.9 5 4 0 5 5 5 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 PVD20281.1 - 2.3e-12 47.1 6.2 0.36 11.2 0.5 6.2 5 1 0 5 5 5 4 Immunoglobulin C1-set domain Ig_6 PF18452.1 PVD20281.1 - 1.6e-06 27.5 0.0 1.6 8.3 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD20281.1 - 8.5e-05 22.5 0.1 3.5 7.7 0.0 4.4 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD20281.1 - 0.0019 18.3 3.5 62 3.9 0.0 5.8 7 0 0 7 7 7 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 PVD20281.1 - 0.1 12.4 6.0 0.51 10.1 0.4 4.1 5 0 0 5 5 5 0 Adenovirus E3 region protein CR1 PX PF00787.24 PVD20282.1 - 3.6e-14 52.7 0.3 4.9e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 PX domain DUF4764 PF15961.5 PVD20282.1 - 0.099 11.3 0.3 0.14 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-SNAP50_C PF12251.8 PVD20283.1 - 3.7e-71 239.0 1.2 4.9e-71 238.6 1.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Ig_3 PF13927.6 PVD20284.1 - 1.8e-10 41.3 0.0 2.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD20284.1 - 2.9e-07 30.5 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD20284.1 - 4.1e-06 26.9 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD20284.1 - 5.2e-05 23.5 0.0 8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 PVD20284.1 - 0.0092 16.4 0.0 1 9.8 0.0 2.1 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD20284.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 PVD20284.1 - 0.063 13.5 0.0 0.48 10.6 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain I-set PF07679.16 PVD20285.1 - 5.5e-08 32.8 0.0 8.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 PVD20285.1 - 2.2e-07 31.0 0.0 3.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD20285.1 - 2.4e-06 28.1 0.0 1.3e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD20285.1 - 1.1e-05 25.5 0.1 0.0001 22.4 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD20285.1 - 0.003 17.8 0.0 0.018 15.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 PVD20285.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD20285.1 - 0.064 13.3 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain SH3_14 PF18343.1 PVD20285.1 - 0.087 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Dda helicase SH3 domain adh_short PF00106.25 PVD20286.1 - 1.6e-44 151.7 0.2 4.4e-44 150.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD20286.1 - 6.1e-31 107.8 0.0 9.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD20286.1 - 1.3e-09 38.2 0.1 2e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD20286.1 - 4.7e-05 23.0 0.1 0.00012 21.7 0.1 1.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD20286.1 - 0.002 17.6 0.0 0.0041 16.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 PVD20286.1 - 0.0027 16.7 0.1 0.0043 16.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PVD20286.1 - 0.036 13.2 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LicD PF04991.13 PVD20290.1 - 4.2e-18 66.3 0.6 1.8e-14 54.5 0.6 2.5 2 0 0 2 2 2 2 LicD family Glycos_transf_2 PF00535.26 PVD20291.1 - 3.6e-21 75.7 0.0 6.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD20291.1 - 5.2e-15 55.8 0.0 7.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PVD20291.1 - 4.2e-06 26.3 0.1 8.4e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PVD20291.1 - 0.00088 19.2 1.3 0.012 15.5 1.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 PVD20292.1 - 7.4e-11 42.4 0.0 9.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain TIR_2 PF13676.6 PVD20293.1 - 7.8e-25 87.8 0.3 8e-24 84.5 0.0 3.1 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 PVD20293.1 - 0.00033 20.4 0.1 0.0015 18.3 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-F_leu_zip PF10473.9 PVD20293.1 - 0.0043 17.1 44.3 0.0059 16.6 23.6 11.3 4 4 5 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 PVD20293.1 - 0.0044 17.6 16.7 0.0044 17.6 16.7 13.7 4 4 7 13 13 13 2 Bone marrow stromal antigen 2 SAM_2 PF07647.17 PVD20293.1 - 0.0078 16.3 0.1 0.033 14.3 0.1 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SlyX PF04102.12 PVD20293.1 - 0.015 15.9 1.6 0.015 15.9 1.6 16.1 6 4 12 19 19 19 0 SlyX UPF0242 PF06785.11 PVD20294.1 - 0.00055 20.1 21.5 0.00055 20.1 21.5 6.6 3 3 4 7 7 7 5 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 PVD20295.1 - 8.6e-05 20.9 39.7 8.6e-05 20.9 39.7 2.6 1 1 2 3 3 3 1 HOOK protein TPR_MLP1_2 PF07926.12 PVD20295.1 - 0.002 18.2 16.4 0.002 18.2 16.4 5.5 1 1 4 5 5 5 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 PVD20295.1 - 0.0028 16.6 74.0 0.054 12.4 16.4 4.1 1 1 3 4 4 4 3 Spc7 kinetochore protein HMMR_N PF15905.5 PVD20295.1 - 0.0033 16.9 42.9 0.0033 16.9 42.9 2.7 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 PVD20295.1 - 0.0036 16.7 13.7 0.0036 16.7 13.7 4.1 1 1 2 4 4 4 2 FAM76 protein Rab5-bind PF09311.11 PVD20295.1 - 0.0094 15.4 7.5 0.0094 15.4 7.5 4.3 1 1 1 2 2 1 1 Rabaptin-like protein FliJ PF02050.16 PVD20295.1 - 0.027 14.7 56.5 0.11 12.8 6.2 4.3 2 1 2 4 4 4 0 Flagellar FliJ protein Shugoshin_N PF07558.11 PVD20295.1 - 0.16 11.9 18.2 0.13 12.1 0.9 6.5 5 1 1 6 6 6 0 Shugoshin N-terminal coiled-coil region Med9 PF07544.13 PVD20295.1 - 0.16 12.1 60.4 1.9 8.7 3.4 7.2 3 2 4 7 7 7 0 RNA polymerase II transcription mediator complex subunit 9 ERM PF00769.19 PVD20295.1 - 0.27 11.0 81.9 0.02 14.8 20.8 3.6 1 1 3 4 4 4 0 Ezrin/radixin/moesin family MscS_porin PF12795.7 PVD20295.1 - 0.31 10.6 63.0 1.8 8.1 23.1 3.7 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF1373 PF07117.11 PVD20295.1 - 1.2 9.1 6.2 1.8 8.5 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Atg14 PF10186.9 PVD20295.1 - 3.6 6.6 60.8 0.026 13.6 14.0 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin PF00261.20 PVD20295.1 - 4.1 6.7 72.6 0.086 12.2 18.0 4.3 1 1 2 4 4 4 0 Tropomyosin Tropomyosin_1 PF12718.7 PVD20295.1 - 4.5 7.4 79.2 0.037 14.2 22.6 4.5 1 1 1 3 3 3 0 Tropomyosin like Fez1 PF06818.15 PVD20295.1 - 6.2 7.2 67.3 2.7 8.4 8.3 3.8 1 1 1 3 3 3 0 Fez1 GAS PF13851.6 PVD20295.1 - 8.3 5.7 73.9 8.8 5.6 30.7 4.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Myticin-prepro PF10690.9 PVD20296.1 - 0.21 11.9 3.7 2 8.7 0.3 2.5 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel KRTAP PF11759.8 PVD20298.1 - 6.9e-08 32.9 2756.9 1.8e+04 -2715.2 2756.9 104.1 1 1 0 1 1 1 0 Keratin-associated matrix KRTAP PF11759.8 PVD20299.1 - 5.5e-07 30.0 130.9 0.16 12.5 17.1 6.6 1 1 1 2 2 2 1 Keratin-associated matrix Keratin_2_head PF16208.5 PVD20299.1 - 0.14 12.3 130.1 0.87 9.7 15.4 6.9 1 1 2 3 3 3 0 Keratin type II head CDC45 PF02724.14 PVD20299.1 - 9 4.5 5.8 11 4.2 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CobW_C PF07683.14 PVD20302.1 - 0.03 14.2 0.0 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain zf-C2H2_4 PF13894.6 PVD20303.1 - 2.1e-31 105.8 111.6 0.00011 22.8 1.7 12.9 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20303.1 - 1.6e-28 97.5 110.9 7.7e-05 22.9 0.9 12.6 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD20303.1 - 2.6e-18 65.6 118.0 0.00012 22.3 0.9 13.3 14 1 1 15 15 15 9 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD20303.1 - 1.4e-13 50.4 102.2 2.9e-07 30.3 1.3 15.1 13 3 0 13 13 13 7 C2H2-type zinc finger zf-met PF12874.7 PVD20303.1 - 1.3e-05 25.4 85.6 0.0013 19.1 1.5 12.2 13 0 0 13 13 13 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 PVD20303.1 - 0.0015 18.8 5.6 0.0015 18.8 5.6 5.5 2 2 2 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD20303.1 - 0.0016 18.6 5.2 0.031 14.6 0.1 12.2 13 1 0 13 13 13 5 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PVD20303.1 - 0.34 11.6 61.7 2.5 8.8 12.3 7.0 2 1 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats WAC_Acf1_DNA_bd PF10537.9 PVD20303.1 - 0.45 11.1 12.2 3.3 8.3 0.3 4.2 3 1 2 5 5 5 0 ATP-utilising chromatin assembly and remodelling N-terminal Tmemb_55A PF09788.9 PVD20304.1 - 1.2e-74 250.5 14.6 1.9e-74 249.9 14.6 1.2 1 0 0 1 1 1 1 Transmembrane protein 55A ThiF PF00899.21 PVD20304.1 - 4.2e-22 78.7 0.6 1.5e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 ThiF family C1_1 PF00130.22 PVD20304.1 - 0.13 12.2 8.4 1.9 8.4 1.2 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.13 PVD20304.1 - 1.7 8.7 10.4 0.8 9.8 0.5 3.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.26 PVD20305.1 - 3.1e-34 115.5 88.3 2.1e-05 24.7 1.1 11.6 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20305.1 - 3.6e-31 105.1 91.0 0.00044 20.9 0.4 12.4 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD20305.1 - 7.6e-29 98.8 82.8 2.9e-05 24.3 0.3 12.5 12 0 0 12 12 12 9 Zinc-finger double domain zf-met PF12874.7 PVD20305.1 - 3.4e-16 59.0 71.3 0.0013 19.0 0.5 12.0 12 0 0 12 12 11 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD20305.1 - 1.4e-12 47.3 82.0 0.00011 22.1 0.3 12.0 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD20305.1 - 7e-09 35.7 67.7 0.006 16.8 0.1 12.9 13 0 0 13 13 13 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD20305.1 - 5.8e-08 32.9 60.5 0.0038 17.5 2.2 7.5 4 3 2 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L31 PF01197.18 PVD20305.1 - 0.0047 17.1 15.6 0.18 12.1 2.0 5.5 2 2 3 6 6 6 1 Ribosomal protein L31 zf-BED PF02892.15 PVD20305.1 - 0.0069 16.4 0.7 0.0069 16.4 0.7 11.2 5 3 4 11 11 11 2 BED zinc finger Elf1 PF05129.13 PVD20305.1 - 0.2 11.7 59.9 0.093 12.8 4.7 7.1 2 2 4 6 6 6 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 PVD20305.1 - 2 8.6 48.3 2.5 8.3 0.3 7.9 8 1 0 8 8 7 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD20305.1 - 6.4 7.2 64.9 1.1 9.6 0.4 10.4 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 PVD20305.1 - 8.2 7.3 49.6 10 6.9 0.6 7.3 1 1 5 7 7 7 0 zinc-ribbon family BRO1 PF03097.18 PVD20306.1 - 4.5e-81 272.6 0.0 6.5e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 PVD20306.1 - 8.3e-18 64.3 6.7 9.6e-18 64.1 3.3 2.5 2 0 0 2 2 2 1 Hr1 repeat PDZ PF00595.24 PVD20306.1 - 1.6e-09 38.0 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD20306.1 - 1.5e-05 24.7 0.8 4.5e-05 23.2 0.5 2.0 2 0 0 2 2 2 1 PDZ domain IMPDH PF00478.25 PVD20307.1 - 2.6e-75 253.6 5.6 3.7e-75 253.1 5.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 PVD20307.1 - 7.2e-05 22.0 2.5 9.1e-05 21.6 1.8 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF5449 PF17528.2 PVD20307.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5449) Aminotran_5 PF00266.19 PVD20308.1 - 3.3e-89 299.4 0.0 3.9e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PVD20308.1 - 7.3e-07 28.7 0.1 1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PVD20308.1 - 0.00014 21.3 0.1 0.00022 20.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 PVD20308.1 - 0.00031 19.6 0.0 0.00056 18.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain 4_1_CTD PF05902.13 PVD20308.1 - 0.036 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Pantoate_transf PF02548.15 PVD20309.1 - 0.0056 16.1 0.0 0.0061 16.0 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PRIMA1 PF16101.5 PVD20310.1 - 0.94 9.5 14.1 0.39 10.8 7.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 PVD20312.1 - 7e-17 61.7 0.1 8.2e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LSM PF01423.22 PVD20313.1 - 6.2e-20 70.7 0.0 8.8e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain BTB_2 PF02214.22 PVD20315.1 - 3.6e-10 40.1 0.7 6.9e-10 39.1 0.7 1.4 1 0 0 1 1 1 1 BTB/POZ domain LSM14 PF12701.7 PVD20316.1 - 8.8e-32 109.0 0.0 1.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 PVD20316.1 - 2.7e-21 76.4 8.7 2.7e-21 76.4 8.7 2.0 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 PVD20316.1 - 2.9e-08 33.7 0.0 6.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TH1 PF04858.13 PVD20317.1 - 5.9e-246 817.7 0.0 1.1e-245 816.8 0.0 1.3 1 0 0 1 1 1 1 TH1 protein TAF4 PF05236.14 PVD20317.1 - 2.1e-71 240.9 12.4 3.6e-71 240.2 12.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 PVD20317.1 - 4e-35 119.8 3.5 7.9e-35 118.8 0.6 2.7 2 0 0 2 2 2 1 NHR1 homology to TAF DUF438 PF04282.13 PVD20317.1 - 0.018 15.0 1.6 0.17 11.9 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF438) ATP-cone PF03477.16 PVD20317.1 - 0.68 10.5 3.1 0.62 10.7 0.1 2.5 2 0 0 2 2 2 0 ATP cone domain AA_permease_2 PF13520.6 PVD20318.1 - 1.8e-29 102.9 31.8 3.3e-29 102.0 31.6 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD20318.1 - 3.1e-14 52.4 29.5 3.6e-14 52.2 28.8 1.3 1 1 0 1 1 1 1 Amino acid permease DUF373 PF04123.13 PVD20318.1 - 2 7.8 23.1 0.032 13.7 6.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1011 PF06237.12 PVD20319.1 - 2.5e-35 120.8 8.7 2.5e-35 120.8 8.7 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) BTB PF00651.31 PVD20319.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF3512 PF12024.8 PVD20320.1 - 4.7e-69 232.5 0.7 1.2e-68 231.2 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 PVD20320.1 - 3.1e-09 36.8 0.2 6.4e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Ribosomal_60s PF00428.19 PVD20320.1 - 4.7 7.9 17.3 0.1 13.2 3.6 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-B_box PF00643.24 PVD20321.1 - 4.6e-09 36.3 36.9 7.5e-06 26.0 11.5 3.5 3 0 0 3 3 3 2 B-box zinc finger CEBP_ZZ PF16366.5 PVD20321.1 - 3.6e-05 23.9 12.2 3.6e-05 23.9 12.2 2.7 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4047 PF13256.6 PVD20321.1 - 0.058 13.6 3.2 5.7 7.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) RNA_Me_trans PF04252.13 PVD20321.1 - 0.098 12.2 1.1 0.19 11.2 1.1 1.5 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Vps51 PF08700.11 PVD20321.1 - 1.1 9.4 11.9 0.64 10.1 2.7 2.9 1 1 2 3 3 3 0 Vps51/Vps67 MPP6 PF10175.9 PVD20322.1 - 6.4e-22 78.5 0.3 6.4e-22 78.5 0.3 1.4 2 0 0 2 2 2 1 M-phase phosphoprotein 6 Mannosyl_trans PF05007.13 PVD20323.1 - 1e-57 196.0 12.8 1.9e-57 195.1 12.8 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 PVD20323.1 - 1.6e-13 50.4 23.2 2.1e-13 50.1 23.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U ALG3 PF05208.13 PVD20323.1 - 0.0016 17.9 11.3 0.75 9.2 7.6 3.0 2 1 0 2 2 2 2 ALG3 protein GT87 PF09594.10 PVD20323.1 - 0.032 13.9 18.5 0.16 11.7 18.5 2.2 1 1 0 1 1 1 0 Glycosyltransferase family 87 XPG_I_2 PF12813.7 PVD20324.1 - 3.3e-11 43.1 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 PVD20324.1 - 4.9e-06 27.0 0.2 1.7e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 PVD20324.1 - 0.048 14.0 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 XPG I-region AA_permease_2 PF13520.6 PVD20327.1 - 5.6e-58 196.8 39.8 7e-58 196.5 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD20327.1 - 6.2e-24 84.4 36.0 9.4e-24 83.8 36.0 1.3 1 0 0 1 1 1 1 Amino acid permease Zip PF02535.22 PVD20327.1 - 0.027 13.7 0.4 0.027 13.7 0.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Med10 PF09748.9 PVD20328.1 - 3.6e-26 91.5 0.5 4e-26 91.4 0.5 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Katanin_con80 PF13925.6 PVD20329.1 - 2.5e-52 177.2 1.0 3.8e-52 176.5 1.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 PVD20329.1 - 1.2e-44 149.4 13.6 1.7e-10 41.3 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD20329.1 - 1.2e-14 54.3 0.0 0.00044 20.5 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD20329.1 - 1.2e-08 35.1 0.0 0.13 12.1 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD20329.1 - 0.0017 17.1 0.2 1.6 7.3 0.0 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PVD20329.1 - 0.013 14.5 0.0 0.12 11.3 0.0 2.5 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PVD20329.1 - 0.033 13.5 0.0 2.5 7.3 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain PD40 PF07676.12 PVD20329.1 - 0.062 13.3 0.1 0.87 9.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CBF_beta PF02312.17 PVD20330.1 - 2.7e-79 264.7 4.9 3.1e-79 264.4 4.9 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit CTNNBL PF08216.11 PVD20330.1 - 0.018 15.2 1.5 0.022 14.9 0.6 1.6 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear UPF0183 PF03676.14 PVD20331.1 - 7.3e-134 446.9 0.0 9.2e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) UQ_con PF00179.26 PVD20332.1 - 2.2e-20 72.7 0.0 3.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VIR_N PF15912.5 PVD20333.1 - 7.9e-68 228.9 8.8 7.9e-68 228.9 8.8 3.7 1 1 1 3 3 3 1 Virilizer, N-terminal MTBP_C PF14920.6 PVD20335.1 - 1.2e-17 64.6 16.4 2.4e-16 60.2 1.7 2.9 2 1 0 3 3 3 2 MDM2-binding MTBP_N PF14918.6 PVD20335.1 - 9.1e-11 41.7 1.4 2.2e-10 40.4 1.4 1.7 1 0 0 1 1 1 1 MDM2-binding DUF4618 PF15397.6 PVD20336.1 - 5.4e-61 206.3 25.0 8e-61 205.7 25.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4407 PF14362.6 PVD20336.1 - 0.99 8.7 18.5 48 3.2 18.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SYS1 PF09801.9 PVD20337.1 - 4.2e-45 153.4 6.4 4.8e-45 153.2 6.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network NADH_B2 PF14813.6 PVD20337.1 - 0.072 12.9 7.7 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 COX4 PF02936.14 PVD20338.1 - 1.5e-56 190.3 0.1 1.7e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UPF0220 PF05255.11 PVD20338.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Vps35 PF03635.17 PVD20339.1 - 2.1e-298 991.9 7.8 2.4e-298 991.7 7.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MOR2-PAG1_N PF14222.6 PVD20339.1 - 0.00041 19.4 0.0 0.0075 15.3 0.0 2.4 2 1 0 2 2 2 1 Cell morphogenesis N-terminal TRF PF08558.10 PVD20339.1 - 0.0033 17.1 1.5 1.5 8.4 0.0 3.3 3 0 0 3 3 3 2 Telomere repeat binding factor (TRF) Urb2 PF10441.9 PVD20339.1 - 0.066 13.1 0.3 0.45 10.4 0.1 2.6 2 1 0 2 2 2 0 Urb2/Npa2 family DUF3883 PF13020.6 PVD20340.1 - 1.4e-19 69.9 0.7 3.1e-19 68.8 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) PrmA PF06325.13 PVD20340.1 - 0.00045 19.7 0.7 0.047 13.1 0.2 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD20340.1 - 0.02 14.4 0.1 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase small domain RIH_assoc PF08454.11 PVD20342.1 - 3.3e-19 68.6 1.3 8.8e-19 67.2 1.3 1.8 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 PVD20342.1 - 9.7e-10 38.1 10.9 2.3e-09 36.9 10.9 1.6 1 0 0 1 1 1 1 Ion transport protein SHR3_chaperone PF08229.11 PVD20342.1 - 0.017 14.1 1.6 0.062 12.3 0.1 2.5 2 0 0 2 2 2 0 ER membrane protein SH3 FliL PF03748.14 PVD20342.1 - 0.29 11.8 1.3 1.1 9.9 0.2 2.4 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL RYDR_ITPR PF01365.21 PVD20343.1 - 5.3e-12 45.6 10.9 1.2e-09 37.8 0.3 4.3 2 1 1 3 3 3 2 RIH domain MIR PF02815.19 PVD20343.1 - 1.2e-08 35.0 0.3 8.4e-07 29.0 0.3 2.6 1 1 0 1 1 1 1 MIR domain RIH_assoc PF08454.11 PVD20343.1 - 0.01 15.6 2.7 0.081 12.8 0.0 3.9 4 1 0 4 4 4 0 RyR and IP3R Homology associated DUF2408 PF10303.9 PVD20343.1 - 2.2 8.8 8.5 0.47 11.0 0.6 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2408) Ins145_P3_rec PF08709.11 PVD20344.1 - 1.3e-23 83.3 0.4 2e-22 79.4 0.8 2.3 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 PVD20344.1 - 0.00046 20.1 1.2 0.92 9.3 0.2 2.6 2 1 0 2 2 2 2 MIR domain Uso1_p115_C PF04871.13 PVD20344.1 - 0.015 15.7 2.1 0.024 15.0 2.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PND PF17949.1 PVD20350.1 - 2.8e-31 108.4 1.8 3.2e-30 104.9 0.0 2.6 2 0 0 2 2 2 1 FANCM pseudonuclease domain SNARE PF05739.19 PVD20350.1 - 3.2e-20 71.8 3.9 8.1e-20 70.6 3.9 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 PVD20350.1 - 4.6e-07 29.7 7.4 4.6e-07 29.7 7.4 1.9 2 0 0 2 2 2 1 Syntaxin GCP_C_terminal PF04130.13 PVD20350.1 - 0.0041 16.6 1.2 0.0041 16.6 1.2 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal T3SS_needle_E PF08988.10 PVD20350.1 - 0.012 15.7 0.0 0.047 13.8 0.0 2.0 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle TRP PF06011.12 PVD20350.1 - 0.04 12.7 0.1 0.048 12.4 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Orf78 PF06024.12 PVD20350.1 - 0.086 13.1 1.1 0.23 11.8 1.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) ETRAMP PF09716.10 PVD20350.1 - 0.1 12.7 1.3 0.16 12.1 1.2 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5345 PF17280.2 PVD20350.1 - 0.2 11.7 5.3 0.057 13.4 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) T2SSF PF00482.23 PVD20350.1 - 0.27 11.2 2.4 0.67 9.9 0.5 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2779 PF11074.8 PVD20350.1 - 0.29 11.6 3.2 2.8 8.4 3.2 2.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) DUF1804 PF08822.11 PVD20350.1 - 0.32 11.0 6.9 0.71 9.8 0.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) DUF1676 PF07898.13 PVD20350.1 - 0.61 10.1 4.2 3.9 7.5 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) ODV-E18 PF10717.9 PVD20350.1 - 0.69 9.8 2.2 1.2 9.0 2.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 COMMD1_N PF17221.3 PVD20350.1 - 0.9 9.9 4.6 0.23 11.8 0.4 2.3 2 1 0 2 2 2 0 COMMD1 N-terminal domain Synaptobrevin PF00957.21 PVD20350.1 - 0.96 9.3 16.6 0.023 14.5 7.2 2.9 3 0 0 3 3 3 0 Synaptobrevin DUF2116 PF09889.9 PVD20350.1 - 2.7 8.0 8.9 0.74 9.8 4.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PHM7_cyt PF14703.6 PVD20350.1 - 2.8 8.1 6.1 1.1 9.5 1.0 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter COG2 PF06148.11 PVD20350.1 - 4 7.5 10.2 0.77 9.9 1.0 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ank_2 PF12796.7 PVD20351.1 - 6e-20 71.6 1.7 6e-11 42.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20351.1 - 1.7e-18 66.7 2.1 3.2e-09 37.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 PVD20351.1 - 1.9e-16 60.3 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 PVD20351.1 - 1.2e-12 47.8 5.4 5.6e-06 26.5 0.6 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20351.1 - 3e-10 39.4 1.8 0.3 11.8 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 PVD20351.1 - 1.8e-08 34.4 10.2 0.013 15.9 0.5 4.6 4 0 0 4 4 4 2 Ankyrin repeat Pkinase_Tyr PF07714.17 PVD20351.1 - 1.1e-05 24.8 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 PVD20351.1 - 0.008 16.4 0.0 0.008 16.4 0.0 2.2 3 0 0 3 3 3 1 Ribonuclease 2-5A Trypsin PF00089.26 PVD20353.1 - 1.4e-26 93.7 0.1 1.8e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 PVD20354.1 - 1.3e-20 74.1 0.0 1.4e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 PVD20355.1 - 5.3e-54 183.4 0.3 6.8e-54 183.0 0.0 1.3 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PVD20355.1 - 0.00016 22.6 0.0 0.00025 22.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Defensin_beta_2 PF13841.6 PVD20355.1 - 0.00097 19.6 3.2 0.0033 17.9 3.2 1.9 1 0 0 1 1 1 1 Beta defensin DUF316 PF03761.15 PVD20355.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 PVD20356.1 - 0.0001 22.2 0.9 0.00063 19.6 0.0 2.1 2 0 0 2 2 2 1 Trypsin Trypsin PF00089.26 PVD20357.1 - 5.2e-21 75.5 0.1 5.9e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 PVD20358.1 - 1.5e-11 44.5 0.2 1.7e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 PVD20359.1 - 3.9e-13 49.7 0.3 4.1e-13 49.6 0.3 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 PVD20359.1 - 0.02 14.6 0.9 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Penaeidin PF05927.11 PVD20359.1 - 0.043 14.6 4.0 0.081 13.7 4.0 1.5 1 0 0 1 1 1 0 Penaeidin Trypsin PF00089.26 PVD20360.1 - 2.9e-11 43.6 0.0 4.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin WD40 PF00400.32 PVD20362.1 - 8.5e-17 61.2 11.6 7.4e-06 26.6 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 PVD20362.1 - 3.1e-05 22.7 0.4 0.019 13.5 0.1 3.0 3 1 1 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 PVD20362.1 - 0.00037 20.7 0.0 0.045 14.1 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 PVD20362.1 - 0.013 15.4 0.9 0.81 9.7 0.3 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Coatomer_WDAD PF04053.14 PVD20362.1 - 0.13 11.2 0.0 1 8.3 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Dishevelled PF02377.15 PVD20363.1 - 0.0097 16.4 0.2 0.012 16.0 0.2 1.1 1 0 0 1 1 1 1 Dishevelled specific domain RVT_1 PF00078.27 PVD20363.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.23 PVD20364.1 - 1.3e-63 214.9 0.1 2.6e-63 213.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.16 PVD20364.1 - 9.1e-37 124.4 0.2 9.4e-19 66.8 0.1 2.5 2 0 0 2 2 2 2 BRK domain Helicase_C PF00271.31 PVD20364.1 - 1.9e-19 70.0 0.0 5.2e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PVD20364.1 - 1e-18 67.0 6.7 4.2e-11 42.6 1.2 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PVD20364.1 - 1.7e-06 28.1 0.0 1.7e-06 28.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PVD20364.1 - 8.2e-06 25.2 0.1 3.7e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Ank_2 PF12796.7 PVD20365.1 - 2.5e-46 156.2 8.3 4e-10 40.2 3.7 7.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20365.1 - 4.9e-41 138.6 15.3 4.6e-10 39.8 0.0 9.5 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD20365.1 - 7.1e-38 128.2 16.2 4.3e-09 36.5 0.8 8.6 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20365.1 - 5.5e-31 103.1 22.3 0.0021 18.4 0.1 12.2 13 1 1 14 14 14 8 Ankyrin repeat Ank PF00023.30 PVD20365.1 - 5.4e-18 64.6 35.0 5.6e-05 23.4 0.5 10.0 11 1 0 11 11 11 5 Ankyrin repeat UPF0167 PF03691.14 PVD20365.1 - 0.062 13.1 1.0 0.29 10.9 0.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) 7tm_3 PF00003.22 PVD20366.1 - 7.8e-24 84.7 4.6 9.7e-24 84.4 4.6 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Fumarate_red_D PF02313.17 PVD20366.1 - 0.094 12.8 2.8 0.13 12.4 1.6 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit D ANF_receptor PF01094.28 PVD20367.1 - 6.3e-61 206.4 0.0 8.4e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD20367.1 - 1.3e-13 51.3 0.8 2.4e-13 50.5 0.8 1.4 1 1 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 PVD20367.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain P63C PF10546.9 PVD20368.1 - 8.7 7.0 19.2 1.1e+02 3.5 0.3 6.4 1 1 8 9 9 9 0 P63C domain Abhydrolase_3 PF07859.13 PVD20369.1 - 1.4e-45 155.8 1.3 4.9e-29 101.7 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PVD20369.1 - 5.9e-05 22.1 0.0 8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 PVD20369.1 - 0.0001 21.4 0.4 0.00058 18.8 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 PVD20369.1 - 0.0065 16.0 0.1 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PVD20369.1 - 0.023 14.0 0.5 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 PVD20369.1 - 0.095 12.2 0.3 0.53 9.8 0.1 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 PVD20369.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RabGAP-TBC PF00566.18 PVD20370.1 - 4.3e-10 39.6 4.0 4.3e-10 39.6 4.0 2.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain WD40 PF00400.32 PVD20370.1 - 2.8e-05 24.8 1.3 5.2 8.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat DER1 PF04511.15 PVD20371.1 - 1e-26 94.1 3.4 1.2e-26 93.8 3.4 1.1 1 0 0 1 1 1 1 Der1-like family CAP_N PF01213.19 PVD20372.1 - 0.16 11.5 0.5 0.25 10.8 0.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAP_GLY PF01302.25 PVD20373.1 - 3.6e-11 42.9 0.0 7.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.11 PVD20373.1 - 0.00017 20.6 52.7 0.019 13.9 14.4 3.7 1 1 2 3 3 3 3 Spc7 kinetochore protein DUF4201 PF13870.6 PVD20373.1 - 0.0011 18.8 44.2 0.071 12.8 13.1 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 PVD20373.1 - 0.003 17.6 57.4 0.022 14.8 21.7 3.7 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 PVD20373.1 - 0.0035 17.6 18.1 0.0035 17.6 18.1 3.9 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 PVD20373.1 - 0.0051 14.4 42.8 0.0071 13.9 42.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_II PF06009.12 PVD20373.1 - 0.074 13.1 27.8 0.11 12.6 10.6 4.0 1 1 2 4 4 4 0 Laminin Domain II MAD PF05557.13 PVD20373.1 - 0.082 11.3 50.1 0.071 11.5 39.2 2.6 1 1 1 2 2 2 0 Mitotic checkpoint protein BLOC1_2 PF10046.9 PVD20373.1 - 0.2 12.0 31.6 0.031 14.6 9.7 4.2 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 PVD20373.1 - 0.48 9.0 32.2 0.47 9.0 22.2 2.3 1 1 1 2 2 2 0 AAA domain OmpH PF03938.14 PVD20373.1 - 0.5 10.7 44.9 0.17 12.2 15.0 4.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) HMMR_N PF15905.5 PVD20373.1 - 0.52 9.7 50.1 0.11 12.0 16.4 3.1 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin PF00261.20 PVD20373.1 - 0.79 9.1 54.8 1.4 8.2 7.4 3.0 1 1 1 2 2 2 0 Tropomyosin NPV_P10 PF05531.12 PVD20373.1 - 0.9 10.1 16.7 6.5 7.3 3.2 4.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 PVD20373.1 - 1.4 8.0 46.5 0.66 9.0 21.5 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 PVD20373.1 - 1.5 9.2 12.3 12 6.3 0.1 3.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 PVD20373.1 - 1.5 8.9 50.0 0.16 12.1 16.8 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 PVD20373.1 - 1.5 8.1 51.4 1.9 7.8 5.3 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 PVD20373.1 - 1.7 8.5 52.2 4.5 7.1 19.5 2.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 PVD20373.1 - 2.5 7.6 44.3 3.6 7.1 29.9 3.3 1 1 1 2 2 2 0 Intermediate filament protein DUF3450 PF11932.8 PVD20373.1 - 2.8 7.2 38.0 0.22 10.8 15.4 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 PVD20373.1 - 3.4 6.4 48.0 0.7 8.7 17.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 PVD20373.1 - 3.7 7.6 50.5 0.16 12.0 7.3 4.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 PVD20373.1 - 4.8 5.2 35.5 2.6 6.1 32.7 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Ribosomal_L3 PF00297.22 PVD20374.1 - 2.5e-19 69.5 4.0 2.5e-19 69.5 4.0 2.5 2 2 2 4 4 4 1 Ribosomal protein L3 TetR_C_8 PF14278.6 PVD20374.1 - 0.12 12.5 0.2 6.3 7.0 0.0 2.6 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region COE1_HLH PF16423.5 PVD20374.1 - 0.15 11.8 0.4 8.3 6.2 0.0 2.7 3 0 0 3 3 3 0 Transcription factor COE1 helix-loop-helix domain NAGPA PF09992.9 PVD20375.1 - 2.6e-40 138.4 0.1 3.7e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase EGF_2 PF07974.13 PVD20375.1 - 3.4e-06 27.3 80.7 0.00017 21.9 7.8 6.9 5 2 0 5 5 5 3 EGF-like domain Laminin_EGF PF00053.24 PVD20375.1 - 0.00062 19.9 15.6 0.00062 19.9 15.6 5.0 1 1 3 4 4 4 1 Laminin EGF domain LapA_dom PF06305.11 PVD20375.1 - 0.46 10.3 2.8 1.1 9.2 2.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Beach PF02138.18 PVD20376.1 - 3.4e-103 344.8 0.0 5e-103 344.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 PVD20376.1 - 8e-18 64.5 10.0 0.0037 18.1 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat PH_BEACH PF14844.6 PVD20376.1 - 3.6e-05 23.8 0.0 0.0017 18.4 0.0 2.5 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH Frtz PF11768.8 PVD20376.1 - 0.0017 16.7 0.4 0.096 11.0 0.1 2.8 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 PVD20376.1 - 0.0018 18.5 1.5 14 6.1 0.2 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 PVD20376.1 - 0.0028 17.5 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Nup160 PF11715.8 PVD20376.1 - 0.0037 16.0 2.7 0.02 13.6 1.1 2.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 PVD20376.1 - 0.0039 16.5 0.0 0.38 10.0 0.0 2.7 2 1 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 PVD20376.1 - 0.06 12.1 0.1 3 6.5 0.1 2.5 1 1 1 2 2 2 0 Nup133 N terminal like AA_permease_2 PF13520.6 PVD20377.1 - 8.7e-18 64.4 13.2 1.1e-17 64.0 13.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD20377.1 - 2.6e-07 29.6 11.6 5.6e-07 28.5 11.6 1.7 1 1 0 1 1 1 1 Amino acid permease DUF872 PF05915.12 PVD20377.1 - 0.011 15.9 1.2 0.011 15.9 1.2 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF5527 PF17665.1 PVD20377.1 - 7.6 6.1 6.6 0.42 10.1 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Ins_beta PF03488.14 PVD20378.1 - 3.4e-07 30.2 3.9 2.5 8.2 0.1 5.1 1 1 4 5 5 5 5 Nematode insulin-related peptide beta type DUF5570 PF17731.1 PVD20378.1 - 0.00093 19.3 4.6 0.58 10.3 0.4 2.8 1 1 1 2 2 2 2 Family of unknown function (DUF5570) zf-HYPF PF07503.12 PVD20378.1 - 0.0012 18.5 9.8 30 4.5 0.0 5.2 5 0 0 5 5 5 1 HypF finger RebB PF11747.8 PVD20378.1 - 0.046 13.8 1.0 3.3 7.9 0.1 2.6 1 1 2 3 3 3 0 Killing trait PHD_3 PF13922.6 PVD20378.1 - 2.5 8.5 7.2 23 5.5 1.8 2.9 1 1 1 2 2 2 0 PHD domain of transcriptional enhancer, Asx Rsm22 PF09243.10 PVD20381.1 - 2.6e-59 200.8 0.0 4.4e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF3811 PF11656.8 PVD20381.1 - 0.032 14.6 0.2 0.032 14.6 0.2 1.7 2 0 0 2 2 2 0 YjbD family (DUF3811) Leo1 PF04004.13 PVD20381.1 - 0.05 13.4 0.4 0.13 12.1 0.3 1.8 1 1 0 1 1 1 0 Leo1-like protein tRNA-synt_2 PF00152.20 PVD20382.1 - 2.1e-80 270.2 0.3 4.9e-80 268.9 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) MDD_C PF18376.1 PVD20382.1 - 3.1e-75 252.0 0.0 6.3e-75 251.0 0.0 1.5 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain tRNA_anti-codon PF01336.25 PVD20382.1 - 6.2e-13 48.5 0.1 1.4e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PVD20382.1 - 3.1e-07 30.1 0.2 0.0033 16.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) GHMP_kinases_N PF00288.26 PVD20382.1 - 2.6e-06 27.5 2.0 2.6e-06 27.5 2.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain OTU PF02338.19 PVD20383.1 - 4e-24 85.5 0.0 1e-23 84.2 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PVD20383.1 - 1e-06 28.4 0.4 0.025 14.0 0.0 3.1 1 1 1 3 3 3 2 Peptidase C65 Otubain Mem_trans PF03547.18 PVD20383.1 - 0.02 13.3 0.3 0.02 13.3 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein FAM184 PF15665.5 PVD20383.1 - 0.17 11.6 20.9 0.3 10.8 20.9 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B MMR1 PF08505.10 PVD20383.1 - 0.41 10.9 7.9 0.57 10.4 7.9 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 PVD20383.1 - 2.2 6.1 9.1 2.6 5.9 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPTA PF01239.22 PVD20384.1 - 1.4e-13 50.1 0.6 8e-10 38.1 0.1 2.9 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 PVD20384.1 - 8.1e-07 29.3 19.1 0.00039 20.7 3.0 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20384.1 - 2.9e-06 27.0 7.2 1.4e-05 24.8 2.7 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 PVD20384.1 - 0.00084 18.9 0.3 0.00084 18.9 0.3 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 PVD20384.1 - 0.0029 17.9 10.1 1.6 9.6 0.1 4.9 3 1 0 3 3 3 1 Leucine Rich Repeat TMEM37 PF15108.6 PVD20384.1 - 0.02 14.8 0.3 0.096 12.6 0.1 2.0 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family LRR_6 PF13516.6 PVD20384.1 - 0.062 13.4 9.5 11 6.3 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Iwr1 PF08574.10 PVD20385.1 - 3.7e-09 37.5 11.5 3.7e-09 37.5 11.5 2.9 3 0 0 3 3 3 1 Transcription factor Iwr1 60KD_IMP PF02096.20 PVD20386.1 - 4.4e-31 108.0 5.7 6e-31 107.6 5.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein AdoHcyase PF05221.17 PVD20387.1 - 3.1e-131 436.9 0.0 5.7e-71 239.1 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PVD20387.1 - 1.1e-80 269.4 1.1 1.9e-80 268.6 1.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PVD20387.1 - 7.9e-08 31.9 0.0 1.6e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PVD20387.1 - 8.2e-05 22.2 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 PVD20387.1 - 0.00073 19.8 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Urocanase PF01175.18 PVD20387.1 - 0.013 15.1 0.3 0.022 14.4 0.3 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain F420_oxidored PF03807.17 PVD20387.1 - 0.037 14.6 0.1 0.091 13.4 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.19 PVD20387.1 - 0.047 12.4 0.1 0.81 8.4 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Shikimate_DH PF01488.20 PVD20387.1 - 0.048 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PVD20387.1 - 0.058 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 PVD20387.1 - 0.097 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase vATP-synt_AC39 PF01992.16 PVD20388.1 - 2.4e-119 398.8 1.0 2.7e-119 398.6 1.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Peptidase_M17 PF00883.21 PVD20389.1 - 6e-97 324.7 0.1 7.7e-97 324.3 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 PVD20389.1 - 3e-26 92.1 0.0 5.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Kelch_1 PF01344.25 PVD20390.1 - 5.7e-41 137.9 12.3 5.1e-12 45.2 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PVD20390.1 - 5e-28 96.4 5.1 1.4e-07 31.5 0.0 6.8 4 2 3 7 7 7 4 Kelch motif BTB PF00651.31 PVD20390.1 - 1e-22 80.4 0.2 1.9e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD20390.1 - 5.4e-20 71.4 1.0 2e-19 69.6 0.3 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD20390.1 - 5.1e-18 64.8 4.4 3e-07 30.3 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD20390.1 - 3e-13 49.7 5.5 0.00034 20.8 0.1 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD20390.1 - 1.2e-09 37.8 7.1 0.012 15.6 0.0 5.3 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PVD20390.1 - 3.8e-09 36.3 6.0 0.019 14.9 0.0 4.9 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.8 PVD20390.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) LRR_4 PF12799.7 PVD20391.1 - 1.5e-08 34.8 6.2 0.0017 18.7 0.0 3.0 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20391.1 - 1.9e-07 30.7 6.8 0.00062 19.5 2.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 PVD20391.1 - 3e-06 26.8 3.1 0.2 11.8 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 PVD20391.1 - 0.042 14.4 5.8 3.8 8.4 0.3 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 PVD20391.1 - 0.064 12.8 0.1 0.85 9.1 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Peptidase_S41_N PF11918.8 PVD20391.1 - 0.1 12.8 0.3 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP CEP76-C2 PF15627.6 PVD20392.1 - 1.8e-52 177.1 0.0 3.1e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 PVD20392.1 - 0.00029 21.3 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 PVD20392.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF553 PF04473.12 PVD20392.1 - 0.062 12.8 0.0 0.42 10.1 0.0 2.0 1 1 0 1 1 1 0 Transglutaminase-like domain TLD PF07534.16 PVD20393.1 - 2.3e-37 128.3 0.4 2.3e-36 125.0 0.1 2.2 2 0 0 2 2 2 1 TLD DLIC PF05783.11 PVD20394.1 - 2.6e-145 484.9 2.4 5.6e-91 305.7 0.0 2.7 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 PVD20394.1 - 0.0029 18.1 0.0 0.0082 16.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 PVD20394.1 - 0.005 17.1 0.1 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PVD20394.1 - 0.026 14.1 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD20394.1 - 0.12 12.3 0.3 25 4.7 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase NOC3p PF07540.11 PVD20394.1 - 0.13 12.8 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 Nucleolar complex-associated protein EGF_2 PF07974.13 PVD20395.1 - 0.2 12.1 6.0 0.46 10.9 6.0 1.7 1 1 0 1 1 1 0 EGF-like domain DUF5554 PF17709.1 PVD20396.1 - 0.068 13.3 0.1 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5554) BTB PF00651.31 PVD20397.1 - 5e-07 29.9 1.2 2.5e-05 24.4 0.2 2.5 1 1 1 2 2 2 2 BTB/POZ domain Hydrophob_seed PF14547.6 PVD20397.1 - 0.0076 16.4 3.3 0.063 13.5 0.6 2.8 1 1 2 3 3 3 1 Hydrophobic seed protein BACK PF07707.15 PVD20397.1 - 0.034 14.3 0.3 0.068 13.3 0.1 1.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch PIP49_C PF12260.8 PVD20398.1 - 3.8e-42 144.1 0.1 4.6e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Ras PF00071.22 PVD20399.1 - 5.5e-59 198.4 0.1 7.1e-59 198.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20399.1 - 1.4e-29 102.7 0.1 3.6e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD20399.1 - 1.4e-11 44.2 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD20399.1 - 0.0014 18.2 0.1 0.0025 17.4 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD20399.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cNMP_binding PF00027.29 PVD20400.1 - 2.1e-13 50.1 0.0 2.7e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ PF00595.24 PVD20401.1 - 1.7e-12 47.5 0.2 2.9e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 PVD20401.1 - 1.4e-11 44.2 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PDZ_6 PF17820.1 PVD20401.1 - 9e-09 35.1 0.1 2.5e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Paf1 PF03985.13 PVD20401.1 - 0.013 14.5 1.0 0.019 14.0 1.0 1.2 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.18 PVD20401.1 - 0.033 14.1 3.5 0.045 13.7 3.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 PVD20401.1 - 0.21 11.1 5.8 0.36 10.4 5.8 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 PVD20401.1 - 0.35 10.3 3.2 0.48 9.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 PVD20401.1 - 4.8 6.4 8.6 6.7 5.9 8.6 1.1 1 0 0 1 1 1 0 NOA36 protein LicD PF04991.13 PVD20402.1 - 8.6e-13 49.0 0.1 8.6e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 LicD family Inositol_P PF00459.25 PVD20403.1 - 4.3e-75 252.7 0.4 5.2e-75 252.5 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1640 PF07798.11 PVD20404.1 - 1.4e-44 152.3 10.8 2.2e-44 151.6 10.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DHC_N2 PF08393.13 PVD20404.1 - 0.00063 19.0 4.0 0.00087 18.5 4.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 JAKMIP_CC3 PF16034.5 PVD20404.1 - 0.011 15.7 4.6 0.018 15.0 4.6 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Phage_T7_Capsid PF05396.11 PVD20404.1 - 0.082 13.3 0.4 0.45 10.9 0.0 2.3 2 2 0 2 2 2 0 Phage T7 capsid assembly protein Arm-DNA-bind_2 PF12167.8 PVD20404.1 - 0.12 12.3 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain TPR_MLP1_2 PF07926.12 PVD20404.1 - 0.13 12.3 6.6 3.9 7.6 0.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Alb1 PF09135.11 PVD20404.1 - 0.27 12.1 4.0 0.21 12.5 1.7 1.9 2 0 0 2 2 2 0 Alb1 AATF-Che1 PF13339.6 PVD20404.1 - 0.36 11.5 5.9 0.84 10.3 5.9 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DLP_helical PF18709.1 PVD20404.1 - 1.5 7.9 10.6 1.3 8.2 0.6 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain COG5 PF10392.9 PVD20404.1 - 1.9 8.6 10.0 0.28 11.3 3.7 2.5 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DHO_dh PF01180.21 PVD20405.1 - 2e-109 365.4 0.0 2.3e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 PVD20405.1 - 0.0025 17.3 0.1 0.0038 16.7 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 PVD20405.1 - 0.021 13.9 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase zf-H2C2_2 PF13465.6 PVD20406.1 - 3.1e-27 93.7 55.1 2.5e-08 34.0 0.1 10.6 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 PVD20406.1 - 4.1e-17 61.6 87.4 9e-05 22.7 0.6 11.5 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20406.1 - 7.9e-17 60.5 87.3 0.0027 18.4 1.6 11.6 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD20406.1 - 5.7e-07 29.2 21.1 1e-05 25.2 0.9 8.4 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 PVD20406.1 - 0.003 17.8 37.1 0.19 12.1 0.9 7.8 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD20406.1 - 0.0064 16.8 55.9 0.071 13.4 8.0 7.3 4 2 3 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 PVD20406.1 - 0.0094 16.3 51.2 0.56 10.6 6.4 7.8 4 1 1 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 PVD20406.1 - 0.01 15.7 1.3 0.01 15.7 1.3 4.5 6 0 0 6 6 6 0 zinc-finger of a C2HC-type AKAP95 PF04988.12 PVD20406.1 - 0.39 11.0 0.0 0.39 11.0 0.0 6.4 6 1 1 8 8 8 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_8 PF15909.5 PVD20406.1 - 0.97 9.8 26.4 0.74 10.1 2.2 4.6 1 1 3 4 4 4 0 C2H2-type zinc ribbon GAGA PF09237.11 PVD20406.1 - 2.4 8.1 8.0 26 4.7 0.1 4.4 4 0 0 4 4 4 0 GAGA factor CD36 PF01130.21 PVD20407.1 - 8.3e-123 410.4 3.3 1.1e-66 225.3 0.3 2.1 2 0 0 2 2 2 2 CD36 family Orthoreo_P10 PF07204.11 PVD20407.1 - 3.4 7.7 5.5 1.3 9.0 0.7 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 UPF0172 PF03665.13 PVD20408.1 - 7.7e-64 215.3 0.2 8.6e-64 215.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Kinesin PF00225.23 PVD20409.1 - 4e-86 289.0 0.0 4e-86 289.0 0.0 5.1 2 2 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 PVD20409.1 - 5.8e-26 91.2 0.1 9.1e-25 87.3 0.0 3.3 2 0 0 2 2 2 1 Microtubule binding Homoserine_dh PF00742.19 PVD20409.1 - 0.11 12.4 0.3 0.58 10.1 0.3 2.3 1 0 0 1 1 1 0 Homoserine dehydrogenase Leu_zip PF15294.6 PVD20409.1 - 1.4 8.3 136.1 0.0078 15.8 10.0 9.1 3 1 6 9 9 9 0 Leucine zipper DUF218 PF02698.17 PVD20410.1 - 2.5e-21 76.1 0.0 3.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Scs3p PF10261.9 PVD20411.1 - 1.4e-25 90.2 10.2 7.2e-24 84.6 10.2 2.1 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 PVD20411.1 - 0.021 14.6 0.3 0.021 14.6 0.3 1.8 2 0 0 2 2 2 0 PAP2 superfamily CD225 PF04505.12 PVD20412.1 - 1.3e-06 28.4 3.7 1.3e-06 28.4 3.7 2.0 2 0 0 2 2 1 1 Interferon-induced transmembrane protein DUF3357 PF11837.8 PVD20412.1 - 0.082 13.4 3.1 1.1 9.8 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) LRR19-TM PF15176.6 PVD20412.1 - 0.2 11.7 0.4 0.49 10.4 0.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ECSCR PF15820.5 PVD20412.1 - 0.58 10.0 0.1 0.58 10.0 0.1 3.4 3 1 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator DUF1218 PF06749.12 PVD20412.1 - 0.65 10.6 12.4 0.27 11.8 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) SDF PF00375.18 PVD20412.1 - 0.9 8.5 15.9 0.048 12.7 6.9 2.0 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family PKD_channel PF08016.12 PVD20412.1 - 0.94 8.1 8.6 0.64 8.6 0.8 2.1 2 0 0 2 2 2 0 Polycystin cation channel Baculo_11_kDa PF06143.11 PVD20412.1 - 2.8 7.6 10.7 1.9 8.1 4.8 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Peptidase_S49_N PF08496.10 PVD20412.1 - 3.4 7.7 5.8 0.23 11.5 0.8 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 PVD20412.1 - 3.6 8.6 6.3 16 6.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SP_C-Propep PF08999.10 PVD20412.1 - 4.4 7.1 12.2 4.2 7.2 8.5 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Ldl_recept_a PF00057.18 PVD20414.1 - 4.5e-07 30.0 8.6 1.2e-06 28.6 8.6 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TMEM171 PF15471.6 PVD20414.1 - 0.087 11.8 0.7 0.16 10.9 0.7 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 DUF4381 PF14316.6 PVD20414.1 - 0.21 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Lamp PF01299.17 PVD20415.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) RT_RNaseH_2 PF17919.1 PVD20417.1 - 4.4e-18 65.2 0.1 2.1e-08 34.1 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD20417.1 - 2.9e-08 33.9 0.1 5e-07 30.0 0.1 2.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_Tn3 PF01526.17 PVD20417.1 - 0.094 11.5 3.9 4.9 5.8 0.1 3.0 2 1 1 3 3 3 0 Tn3 transposase DDE domain Med14 PF08638.11 PVD20417.1 - 0.17 11.3 0.1 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 DDE_Tnp_4 PF13359.6 PVD20418.1 - 7.7e-25 87.4 0.0 1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 PVD20418.1 - 4e-06 26.6 0.0 5.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Hemocyanin_N PF03722.14 PVD20418.1 - 0.014 15.9 0.0 0.036 14.6 0.0 1.6 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain TUDOR PF00567.24 PVD20420.1 - 2.5e-43 147.0 5.3 5.4e-14 52.3 0.0 4.8 4 0 0 4 4 4 4 Tudor domain DEAD PF00270.29 PVD20420.1 - 2.4e-20 73.0 0.0 7.8e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase CS PF04969.16 PVD20420.1 - 1.1e-05 26.3 0.3 0.00017 22.6 0.0 2.8 2 0 0 2 2 2 1 CS domain V-ATPase_H_N PF03224.14 PVD20420.1 - 0.001 18.5 1.8 0.001 18.5 1.8 2.4 3 0 0 3 3 3 1 V-ATPase subunit H ANAPC3 PF12895.7 PVD20421.1 - 0.12 12.6 0.1 0.4 10.9 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Alpha_kinase PF02816.18 PVD20422.1 - 1.3e-34 120.0 0.0 1.8e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_M41 PF01434.18 PVD20423.1 - 9.5e-63 211.5 0.1 1.5e-62 210.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PVD20423.1 - 6.1e-41 139.9 0.0 5.9e-40 136.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD20423.1 - 9.6e-15 54.1 0.0 3.2e-14 52.4 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain FtsH_ext PF06480.15 PVD20423.1 - 2e-08 34.6 0.0 9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 PVD20423.1 - 1.2e-05 25.3 0.0 4.5e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD20423.1 - 8.3e-05 22.9 0.0 0.045 14.0 0.0 3.9 5 1 0 6 6 6 1 AAA domain AAA_2 PF07724.14 PVD20423.1 - 0.00065 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 PVD20423.1 - 0.00087 19.7 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PVD20423.1 - 0.00097 18.9 0.2 0.0046 16.7 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PVD20423.1 - 0.0013 19.1 0.1 0.0054 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 PVD20423.1 - 0.0037 16.5 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 PVD20423.1 - 0.0098 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PVD20423.1 - 0.038 13.7 0.3 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PVD20423.1 - 0.059 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 PVD20423.1 - 0.12 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Peptidase_M50B PF13398.6 PVD20423.1 - 0.12 12.0 0.1 0.36 10.4 0.1 1.7 1 0 0 1 1 1 0 Peptidase M50B-like AAA_18 PF13238.6 PVD20423.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_5 PF13857.6 PVD20424.1 - 3.6e-21 74.9 0.3 3.3e-09 36.8 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20424.1 - 4.2e-19 68.9 0.6 4.6e-12 46.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD20424.1 - 3.2e-18 65.3 0.3 3.5e-05 24.0 0.4 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PVD20424.1 - 3.6e-17 62.5 0.0 5.7e-05 23.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20424.1 - 1.4e-14 52.7 0.0 3.2e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Pro_isomerase PF00160.21 PVD20425.1 - 2.3e-44 151.4 0.0 2.9e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CMS1 PF14617.6 PVD20425.1 - 0.076 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Pro_isomerase PF00160.21 PVD20426.1 - 1.1e-33 116.8 0.6 7.4e-18 65.3 0.0 2.1 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 PVD20427.1 - 8.9e-72 241.6 0.0 1.6e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20427.1 - 8.3e-40 136.7 0.0 1.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD20427.1 - 7.6e-08 32.0 0.0 6.9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PVD20427.1 - 0.027 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.9 PVD20427.1 - 8.7 4.8 16.3 15 4.0 16.3 1.4 1 0 0 1 1 1 0 Macoilin family PAN_1 PF00024.26 PVD20428.1 - 9.3e-08 31.9 13.3 0.00031 20.6 1.4 3.3 1 1 2 3 3 3 2 PAN domain EB PF01683.18 PVD20428.1 - 0.0032 17.7 14.9 0.0032 17.7 14.9 2.6 2 1 0 2 2 2 1 EB module PAN_2 PF08276.11 PVD20428.1 - 0.0041 17.2 0.4 0.0041 17.2 0.4 2.8 2 1 1 3 3 3 1 PAN-like domain PAN_4 PF14295.6 PVD20428.1 - 0.013 15.4 1.4 0.013 15.4 1.4 3.3 3 2 0 3 3 3 0 PAN domain PAN_3 PF08277.12 PVD20428.1 - 0.02 14.7 5.6 0.042 13.6 1.6 2.5 2 0 0 2 2 2 0 PAN-like domain CPSF_A PF03178.15 PVD20429.1 - 7.3e-89 298.3 0.0 9.6e-87 291.3 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.9 PVD20429.1 - 2.9e-44 151.6 0.0 9.2e-44 149.9 0.0 1.8 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PEP-utilizers PF00391.23 PVD20430.1 - 1.5e-20 72.7 0.1 2.8e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 PVD20431.1 - 4.3e-77 259.6 0.2 5.9e-77 259.1 0.2 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain zf-RING_UBOX PF13445.6 PVD20432.1 - 2.8e-10 40.1 7.7 2.8e-10 40.1 7.7 4.2 4 1 1 5 5 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD20432.1 - 3.7e-09 36.3 8.2 3.7e-09 36.3 8.2 4.4 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD20432.1 - 7.8e-08 32.0 6.6 7.8e-08 32.0 6.6 4.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD20432.1 - 7.3e-07 29.4 11.1 7.3e-07 29.4 11.1 4.5 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 PVD20432.1 - 1.1e-05 25.3 9.7 1.1e-05 25.3 9.7 3.9 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD20432.1 - 1.9e-05 24.4 10.4 1.9e-05 24.4 10.4 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD20432.1 - 0.00012 22.2 9.5 0.00012 22.2 9.5 4.2 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD20432.1 - 0.00012 22.1 14.8 0.00012 22.1 14.8 3.9 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD20432.1 - 0.0002 21.2 8.2 0.0002 21.2 8.2 3.8 3 1 0 3 3 1 1 Prokaryotic RING finger family 4 NHL PF01436.21 PVD20432.1 - 0.0025 17.8 0.0 4.4 7.5 0.0 3.5 4 0 0 4 4 4 1 NHL repeat PQQ_2 PF13360.6 PVD20432.1 - 0.0027 17.3 0.0 0.021 14.4 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain SepF PF04472.12 PVD20432.1 - 0.096 13.0 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 Cell division protein SepF zf-RING_11 PF17123.5 PVD20432.1 - 0.29 10.9 5.6 0.86 9.4 3.8 2.9 2 0 0 2 2 2 0 RING-like zinc finger GST_N_3 PF13417.6 PVD20433.1 - 5.3e-14 52.4 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD20433.1 - 9.3e-12 45.1 0.0 2.3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD20433.1 - 6.5e-10 39.2 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD20433.1 - 4.2e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD20433.1 - 0.00092 19.4 0.0 0.0048 17.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EcsC PF12787.7 PVD20433.1 - 0.0011 18.7 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 2 EcsC protein family Tom37 PF10568.9 PVD20433.1 - 0.0022 18.3 0.0 0.0073 16.6 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 PVD20433.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD20433.1 - 0.0087 16.8 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF5446 PF17522.2 PVD20433.1 - 0.038 14.1 0.4 0.038 14.1 0.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5446) TrkH PF02386.16 PVD20434.1 - 1.6 7.1 7.1 4 5.8 0.1 2.9 1 1 2 3 3 3 0 Cation transport protein DUF3654 PF12376.8 PVD20435.1 - 0.084 13.1 0.4 0.098 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Arrestin_N PF00339.29 PVD20436.1 - 1.3e-16 61.0 0.0 8.6e-06 25.9 0.0 3.4 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD20436.1 - 1.2e-13 51.7 0.5 3.2e-13 50.3 0.5 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_60s PF00428.19 PVD20436.1 - 1.1 9.9 11.4 3 8.5 2.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Na_H_Exchanger PF00999.21 PVD20438.1 - 6.4e-80 268.8 37.4 8.2e-80 268.4 37.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF848 PF05852.11 PVD20439.1 - 0.026 14.6 2.8 0.037 14.1 2.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3552 PF12072.8 PVD20439.1 - 0.077 12.4 7.3 0.088 12.2 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FapA PF03961.13 PVD20439.1 - 0.52 8.9 2.6 0.65 8.5 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HHH_3 PF12836.7 PVD20441.1 - 2.1e-40 136.8 0.3 6.1e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 PVD20441.1 - 5.5e-15 54.4 0.1 0.00064 19.5 0.0 4.4 4 0 0 4 4 4 4 Helix-hairpin-helix motif HHH_6 PF14579.6 PVD20441.1 - 3.5e-07 30.4 0.0 0.00049 20.3 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 PVD20441.1 - 3e-06 27.2 0.4 0.38 10.9 0.0 3.7 4 0 0 4 4 4 2 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 PVD20441.1 - 1.4e-05 24.7 0.0 4.8e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family T2SSK PF03934.13 PVD20441.1 - 1.4e-05 24.6 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K HHH_5 PF14520.6 PVD20441.1 - 5.1e-05 23.8 1.2 1.3 9.7 0.0 4.9 4 1 1 5 5 5 1 Helix-hairpin-helix domain PsbU PF06514.11 PVD20441.1 - 8.4e-05 22.5 0.1 0.0036 17.3 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_8 PF14716.6 PVD20441.1 - 0.039 14.3 0.0 48 4.4 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain LCAT PF02450.15 PVD20442.1 - 6.8e-27 94.6 0.3 2.7e-12 46.6 0.0 3.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase CBM_21 PF03370.13 PVD20444.1 - 7e-26 90.6 0.1 1.2e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 PVD20444.1 - 1.8e-11 44.4 1.0 3.6e-11 43.5 1.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF1707 PF08044.11 PVD20444.1 - 0.069 13.2 0.2 0.26 11.4 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) BRCT_assoc PF12820.7 PVD20444.1 - 6.9 6.5 6.9 1.7 8.5 3.0 1.9 2 0 0 2 2 2 0 Serine-rich domain associated with BRCT tRNA-synt_2d PF01409.20 PVD20445.1 - 3.8e-47 160.8 0.2 5e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 PVD20445.1 - 4e-21 75.2 0.0 8.4e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 PVD20445.1 - 0.028 13.5 0.0 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) DUF2267 PF10025.9 PVD20445.1 - 0.072 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Na_Pi_cotrans PF02690.15 PVD20447.1 - 5.3e-34 117.3 21.5 1.6e-24 86.6 5.7 2.9 2 1 0 2 2 2 2 Na+/Pi-cotransporter OAS1_C PF10421.9 PVD20448.1 - 4.6e-14 52.3 0.1 1e-13 51.2 0.1 1.5 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.23 PVD20448.1 - 1.7e-05 25.1 0.0 2.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 PVD20448.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain CTD_bind PF04818.13 PVD20448.1 - 0.12 13.2 0.2 0.3 11.9 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. SMODS PF18144.1 PVD20449.1 - 3e-08 34.0 0.0 4.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 PVD20449.1 - 8.5e-08 32.4 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PVD20449.1 - 0.0068 16.5 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase OAS1_C PF10421.9 PVD20450.1 - 1.1e-15 57.7 0.0 2.4e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus SMODS PF18144.1 PVD20450.1 - 1.4e-06 28.6 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 PVD20450.1 - 7.6e-06 26.1 0.1 2e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain CTD_bind PF04818.13 PVD20450.1 - 0.028 15.2 0.0 0.082 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. OAS1_C PF10421.9 PVD20451.1 - 4.3e-14 52.4 0.1 1.2e-13 50.9 0.1 1.7 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus SMODS PF18144.1 PVD20451.1 - 3.8e-08 33.7 0.0 5.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 PVD20451.1 - 8.7e-07 29.2 1.2 2.1e-06 28.0 0.3 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain ACP_PD PF04336.12 PVD20451.1 - 0.017 15.6 0.1 0.21 12.0 0.0 2.5 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase CTD_bind PF04818.13 PVD20451.1 - 0.028 15.2 0.5 0.088 13.7 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF883 PF05957.13 PVD20451.1 - 0.11 13.2 2.2 2.8 8.6 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) APCDDC PF14921.6 PVD20453.1 - 7e-74 248.2 2.2 4.6e-61 206.3 0.2 2.1 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 Aminotran_3 PF00202.21 PVD20454.1 - 2.8e-08 32.9 0.0 3.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF4862 PF16154.5 PVD20454.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4862) Lectin_C PF00059.21 PVD20455.1 - 0.00031 21.4 2.0 0.00031 21.4 2.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain DUF496 PF04363.12 PVD20455.1 - 0.17 12.0 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF496) CARD_2 PF16739.5 PVD20457.1 - 8.4e-09 35.3 0.4 0.00031 20.7 0.1 2.4 2 0 0 2 2 2 2 Caspase recruitment domain TRH PF05438.12 PVD20457.1 - 0.033 13.9 0.5 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) PEHE PF15275.6 PVD20457.1 - 0.041 14.5 0.2 0.085 13.5 0.1 1.6 2 0 0 2 2 2 0 PEHE domain DUF3549 PF12069.8 PVD20457.1 - 0.052 12.6 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF2458 PF10454.9 PVD20457.1 - 0.053 13.2 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Curlin_rpt PF07012.12 PVD20457.1 - 0.08 13.0 1.2 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Curlin associated repeat FHIPEP PF00771.20 PVD20457.1 - 0.24 9.8 0.1 0.3 9.5 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family CARD_2 PF16739.5 PVD20458.1 - 1.2e-14 54.0 1.0 1.3e-10 41.2 0.2 2.4 2 0 0 2 2 2 2 Caspase recruitment domain CARD PF00619.21 PVD20458.1 - 0.001 19.0 2.0 0.012 15.7 0.5 2.9 3 0 0 3 3 3 1 Caspase recruitment domain DUF4599 PF15371.6 PVD20458.1 - 0.38 11.3 4.6 1.2 9.7 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) LIM PF00412.22 PVD20459.1 - 9.7e-31 105.8 42.9 1e-12 48.1 10.2 3.3 3 0 0 3 3 3 3 LIM domain Mst1_SARAH PF11629.8 PVD20459.1 - 0.14 12.3 0.2 21 5.3 0.0 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 MORN PF02493.20 PVD20460.1 - 5.8e-36 120.3 49.7 9.3e-07 28.4 2.6 9.4 9 0 0 9 9 9 9 MORN repeat Gal-bind_lectin PF00337.22 PVD20460.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Galactoside-binding lectin Mago_nashi PF02792.14 PVD20460.1 - 2 8.5 4.7 0.42 10.7 0.6 2.0 2 0 0 2 2 2 0 Mago nashi protein EF-hand_1 PF00036.32 PVD20461.1 - 3.5e-09 35.5 1.2 3.5e-05 23.0 0.9 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD20461.1 - 6.3e-08 31.9 4.7 0.00069 19.4 0.3 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD20461.1 - 2.3e-07 31.2 6.7 1e-05 25.9 1.3 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD20461.1 - 1.8e-06 27.2 3.7 1.6e-05 24.2 0.7 3.3 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PVD20461.1 - 1.8e-06 27.7 1.5 0.0025 17.6 0.4 2.8 2 0 0 2 2 2 2 EF-hand domain pair ABM PF03992.16 PVD20461.1 - 7.9e-05 22.7 0.0 0.00025 21.1 0.0 1.9 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PriC PF07445.12 PVD20461.1 - 0.014 15.3 0.1 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 Primosomal replication protein priC Prefoldin_2 PF01920.20 PVD20462.1 - 2.9e-19 69.0 13.3 3.6e-19 68.7 13.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit AAA_13 PF13166.6 PVD20462.1 - 0.001 17.8 11.2 0.0011 17.7 11.2 1.0 1 0 0 1 1 1 1 AAA domain DUF5082 PF16888.5 PVD20462.1 - 0.017 15.4 10.2 0.033 14.5 10.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3958 PF13125.6 PVD20462.1 - 0.022 15.0 5.9 0.028 14.6 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Seryl_tRNA_N PF02403.22 PVD20462.1 - 0.047 13.9 12.5 0.56 10.4 0.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Med9 PF07544.13 PVD20462.1 - 0.083 13.0 8.7 1.5 9.0 7.3 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 PVD20462.1 - 0.087 13.2 7.3 3 8.3 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Med30 PF11315.8 PVD20462.1 - 0.31 11.2 7.4 0.49 10.6 7.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 MMPL PF03176.15 PVD20462.1 - 0.4 9.6 2.7 0.44 9.4 2.7 1.0 1 0 0 1 1 1 0 MMPL family Spc24 PF08286.11 PVD20462.1 - 0.5 10.6 11.7 5.8 7.2 11.7 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 PVD20462.1 - 0.52 11.0 10.3 0.6 10.8 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA XhlA PF10779.9 PVD20462.1 - 0.8 9.9 6.9 1.8 8.8 0.1 2.6 2 1 1 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 PVD20462.1 - 1.1 9.5 8.0 2.5 8.3 6.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 PVD20462.1 - 1.1 9.2 11.7 0.85 9.6 2.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 PVD20462.1 - 1.1 7.1 6.5 1.4 6.7 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 PVD20462.1 - 2.1 8.4 14.4 8.6 6.4 14.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5339 PF17274.2 PVD20462.1 - 2.2 9.2 11.2 5.7 7.9 1.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DivIC PF04977.15 PVD20462.1 - 3.4 7.5 10.8 9.2 6.1 0.3 2.5 2 1 0 2 2 2 0 Septum formation initiator MRP-L28 PF09812.9 PVD20462.1 - 3.7 7.7 9.5 4.5 7.4 4.3 2.1 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L28 FAM76 PF16046.5 PVD20462.1 - 4 6.7 9.6 5.1 6.4 9.6 1.1 1 0 0 1 1 1 0 FAM76 protein Thioredoxin PF00085.20 PVD20463.1 - 2.2e-25 88.6 0.0 1e-24 86.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 PVD20463.1 - 7.4e-16 58.6 0.2 7e-12 45.6 0.4 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PVD20463.1 - 2e-05 25.0 0.0 8.4e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PVD20463.1 - 0.031 14.6 0.1 2.4 8.6 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 PVD20463.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DUF1772 PF08592.11 PVD20463.1 - 0.088 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) TraF PF13728.6 PVD20463.1 - 0.33 10.7 1.6 0.64 9.8 0.0 2.3 4 0 0 4 4 4 0 F plasmid transfer operon protein PH_8 PF15409.6 PVD20465.1 - 0.023 15.0 0.1 0.1 12.9 0.0 1.8 1 1 1 2 2 2 0 Pleckstrin homology domain uDENN PF03456.18 PVD20467.1 - 0.015 16.0 0.6 1.2 9.9 0.6 2.4 1 1 0 1 1 1 0 uDENN domain MerB PF03243.15 PVD20467.1 - 0.032 14.4 0.0 0.085 13.0 0.0 1.8 2 0 0 2 2 2 0 Alkylmercury lyase PH PF00169.29 PVD20472.1 - 7.6e-10 39.2 0.1 2.5e-09 37.6 0.1 1.8 1 1 0 1 1 1 1 PH domain DUF2076 PF09849.9 PVD20472.1 - 0.00013 22.1 14.6 0.00013 22.1 14.6 2.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) PH_9 PF15410.6 PVD20472.1 - 0.18 12.2 0.6 4.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 PVD20472.1 - 0.2 12.1 0.8 8.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain TFIIA PF03153.13 PVD20472.1 - 8.7 6.2 16.3 12 5.8 16.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3689 PF12463.8 PVD20473.1 - 1.8e-134 448.0 9.9 1.8e-134 448.0 9.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3689) CENP-N PF05238.13 PVD20473.1 - 1.7e-19 70.5 0.0 3.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Kinetochore protein CHL4 like ECH_1 PF00378.20 PVD20474.1 - 2.1e-23 82.9 0.0 2.6e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD20474.1 - 9.3e-08 31.9 0.0 1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase COX2 PF00116.20 PVD20475.1 - 0.00028 20.8 0.4 12 5.9 0.0 3.5 1 1 4 5 5 5 5 Cytochrome C oxidase subunit II, periplasmic domain DUF4755 PF15947.5 PVD20475.1 - 0.28 11.2 0.8 46 4.0 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4755) Ribonucleas_3_3 PF14622.6 PVD20476.1 - 6.7e-07 29.5 0.2 1.8e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Sec5 PF15469.6 PVD20477.1 - 2.5e-45 154.6 2.7 2.9e-45 154.4 0.5 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 TIG PF01833.24 PVD20477.1 - 2.9e-08 33.6 0.1 6.8e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain RINT1_TIP1 PF04437.13 PVD20477.1 - 0.027 13.4 0.0 0.097 11.5 0.0 1.9 2 0 0 2 2 2 0 RINT-1 / TIP-1 family NRIP1_repr_1 PF15687.5 PVD20477.1 - 0.061 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 Arm PF00514.23 PVD20478.1 - 0.00011 22.1 9.0 0.00037 20.4 0.2 5.4 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PVD20478.1 - 0.0079 16.7 0.7 0.0079 16.7 0.7 4.4 4 1 1 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 PVD20478.1 - 0.026 14.7 0.6 19 5.5 0.0 4.6 4 2 2 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 PVD20478.1 - 0.041 13.6 0.2 0.28 10.9 0.1 2.5 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis Hydin_ADK PF17213.3 PVD20478.1 - 0.068 13.4 0.7 0.13 12.5 0.7 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mn_catalase PF05067.12 PVD20478.1 - 0.068 12.1 0.1 0.33 9.9 0.0 2.1 3 0 0 3 3 3 0 Manganese containing catalase DUF4611 PF15387.6 PVD20479.1 - 0.025 14.8 0.3 0.036 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Kringle PF00051.18 PVD20480.1 - 1.9e-21 76.2 23.6 5.3e-10 39.5 0.2 3.7 2 1 1 3 3 3 3 Kringle domain Ank_2 PF12796.7 PVD20481.1 - 3.3e-21 75.7 0.1 8e-07 29.6 0.0 5.3 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD20481.1 - 1.1e-17 62.2 1.8 0.00041 20.6 0.0 8.8 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 PVD20481.1 - 2.6e-16 59.7 2.1 2.1e-05 25.0 0.1 7.4 6 3 3 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD20481.1 - 1.5e-10 41.0 0.0 0.35 11.4 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PVD20481.1 - 4.7e-10 39.5 0.6 0.012 15.9 0.0 5.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Proteasome PF00227.26 PVD20482.1 - 9.7e-48 162.2 0.2 1.2e-47 161.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit TIM21 PF08294.11 PVD20483.1 - 1.7e-39 135.0 0.1 2e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 PVD20483.1 - 8.3e-07 28.8 0.0 1.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Reprolysin_5 PF13688.6 PVD20484.1 - 6.6e-25 88.4 1.1 6.6e-25 88.4 1.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD20484.1 - 2.1e-20 73.4 0.2 2.1e-20 73.4 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD20484.1 - 2.6e-14 53.8 0.1 1e-13 51.9 0.1 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD20484.1 - 4.3e-08 33.3 0.0 6.4e-07 29.5 0.0 2.6 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD20484.1 - 1.2e-05 25.1 0.2 4.3e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ARD PF03079.14 PVD20484.1 - 0.072 13.3 0.1 0.072 13.3 0.1 1.8 2 0 0 2 2 2 0 ARD/ARD' family Reprolysin_2 PF13574.6 PVD20485.1 - 2.3e-25 89.6 0.0 5.9e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD20485.1 - 1.3e-24 87.4 0.2 3.6e-24 86.0 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD20485.1 - 5e-12 46.4 0.0 1.1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD20485.1 - 2.8e-09 37.6 24.0 2.8e-09 37.6 24.0 3.0 3 0 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 PVD20485.1 - 7.1e-05 22.5 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD20485.1 - 0.008 16.1 2.8 0.042 13.7 0.0 2.8 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 PVD20485.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.11 PVD20485.1 - 0.089 12.8 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 TcdB_toxin_midN PF12256.8 PVD20485.1 - 0.1 12.0 1.0 1.8 7.9 0.2 2.5 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DEAD PF00270.29 PVD20486.1 - 7.1e-67 224.6 0.0 1e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 PVD20486.1 - 3.4e-22 78.8 0.2 7.4e-22 77.7 0.2 1.6 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.31 PVD20486.1 - 4.9e-05 23.6 0.4 0.0018 18.6 0.1 2.6 1 1 1 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PVD20486.1 - 0.0042 16.5 0.3 0.04 13.2 0.0 2.5 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit TPR_12 PF13424.6 PVD20487.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat PX PF00787.24 PVD20487.1 - 0.0088 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 PX domain DMPK_coil PF08826.10 PVD20487.1 - 0.12 12.6 0.4 11 6.2 0.1 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like BTB PF00651.31 PVD20488.1 - 7.7e-16 58.3 0.7 2e-15 57.0 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 PVD20488.1 - 2.9e-13 49.6 62.7 4e-06 27.0 0.5 9.3 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD20488.1 - 3.3e-12 46.1 77.8 0.02 15.3 0.8 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20488.1 - 1.2e-09 38.2 70.6 0.0098 16.7 0.5 9.5 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD20488.1 - 1.7e-06 27.6 69.7 0.0012 18.6 0.8 8.9 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 PVD20488.1 - 0.0096 16.2 44.4 0.82 10.0 10.4 6.7 1 1 5 6 6 6 1 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 PVD20488.1 - 0.014 15.0 0.0 0.014 15.0 0.0 7.4 4 2 4 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 PVD20488.1 - 0.027 14.7 0.9 0.027 14.7 0.9 3.4 3 0 0 3 3 2 0 zinc-ribbon DP-EP PF08985.11 PVD20488.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.3 2 0 0 2 2 2 0 DP-EP family zf-C2H2_jaz PF12171.8 PVD20488.1 - 0.2 12.0 0.1 0.2 12.0 0.1 6.8 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD20488.1 - 0.56 10.0 9.2 0.15 11.9 0.7 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type ADK_lid PF05191.14 PVD20488.1 - 4.1 7.5 6.8 1.7 8.7 0.8 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 PVD20488.1 - 4.7 8.0 23.3 9.7 7.0 0.4 4.6 2 1 2 4 4 4 0 zinc-ribbon family p450 PF00067.22 PVD20489.1 - 4.1e-88 296.2 0.0 6e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 PVD20490.1 - 7.8e-27 94.3 0.0 1.6e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PVD20490.1 - 8.4e-21 74.7 0.0 1e-19 71.2 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PVD20490.1 - 8.1e-18 65.1 0.0 3.7e-16 59.7 0.0 2.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain 7tm_1 PF00001.21 PVD20491.1 - 1.7e-51 175.1 15.8 2.1e-51 174.8 15.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD20491.1 - 3.5e-11 43.0 14.7 5.4e-11 42.4 14.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD20491.1 - 2.2e-10 40.6 10.1 2.2e-10 40.6 10.1 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD20491.1 - 2e-09 37.6 8.9 2e-09 37.6 8.9 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 PVD20491.1 - 1.4e-05 24.6 14.3 9.6e-05 21.8 14.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw OSTbeta PF15048.6 PVD20491.1 - 0.32 11.2 1.8 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein Vma12 PF11712.8 PVD20491.1 - 0.75 9.9 3.1 13 5.9 0.0 2.6 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Herpes_US9 PF06072.11 PVD20491.1 - 1.2 9.0 4.4 0.36 10.7 0.2 2.3 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RVT_1 PF00078.27 PVD20492.1 - 1.6e-05 24.6 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_22 PF13383.6 PVD20494.1 - 5.2e-18 65.5 0.1 6.8e-18 65.2 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20494.1 - 2.7e-05 24.3 0.0 4.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20494.1 - 0.052 13.8 0.1 0.074 13.3 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20495.1 - 1.9e-12 47.3 0.0 2.4e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20495.1 - 6.9e-06 26.2 0.0 1e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20495.1 - 0.097 12.9 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20496.1 - 5.8e-18 65.4 0.0 6.8e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20496.1 - 7.3e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20496.1 - 0.11 12.8 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PT PF04886.12 PVD20497.1 - 8.4e-08 31.6 34.5 2.5e-06 26.9 34.5 2.2 1 1 0 1 1 1 1 PT repeat Methyltransf_22 PF13383.6 PVD20497.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20497.1 - 2.1e-05 24.6 0.0 3.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4106 PF13388.6 PVD20497.1 - 0.012 14.9 10.0 0.016 14.4 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TMF_TATA_bd PF12325.8 PVD20497.1 - 0.033 14.4 0.1 0.062 13.5 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20498.1 - 6.2e-11 42.3 0.0 7.4e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20498.1 - 4e-06 27.0 0.0 1.9e-05 24.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20498.1 - 0.031 14.5 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20499.1 - 2.4e-18 66.6 0.0 2.9e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20499.1 - 1.5e-05 25.1 0.0 2.2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20499.1 - 0.099 12.9 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20500.1 - 9.3e-21 74.5 0.6 1.2e-20 74.2 0.6 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20500.1 - 1.9e-05 24.7 0.1 3.9e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain adh_short PF00106.25 PVD20501.1 - 1.4e-35 122.6 0.0 1.5e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD20501.1 - 3e-26 92.4 0.0 4.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_22 PF13383.6 PVD20501.1 - 3.4e-21 76.0 0.6 3.4e-21 76.0 0.6 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20501.1 - 6.7e-07 29.5 0.0 3.3e-06 27.2 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase FkbM domain KR PF08659.10 PVD20501.1 - 6.7e-05 22.9 0.0 0.00016 21.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Metallophos PF00149.28 PVD20502.1 - 5.3e-07 30.3 0.0 5.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PVD20502.1 - 0.0015 18.7 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-C2H2_4 PF13894.6 PVD20504.1 - 5.3e-44 145.1 155.7 0.00054 20.6 1.1 20.6 20 0 0 20 20 20 17 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20504.1 - 1.5e-42 141.7 164.6 0.00074 19.8 0.2 20.1 20 0 0 20 20 20 17 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD20504.1 - 7.7e-35 117.8 130.8 3.7e-10 39.8 1.0 23.2 22 2 0 22 22 22 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 PVD20504.1 - 5.6e-09 35.6 17.3 1e-07 31.5 1.7 14.5 15 1 0 15 15 13 6 C2H2-type zinc-finger domain zf-met PF12874.7 PVD20504.1 - 1.3e-08 35.0 88.6 0.0098 16.3 0.4 15.1 16 0 0 16 16 15 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD20504.1 - 9e-05 22.7 91.4 0.09 13.1 0.0 18.5 20 0 0 20 20 20 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD20504.1 - 0.0006 19.7 0.3 0.0006 19.7 0.3 15.6 18 0 0 18 18 18 7 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PVD20504.1 - 0.0024 18.2 6.3 0.0024 18.2 6.3 17.0 8 7 9 18 18 18 5 C2H2 type zinc-finger (2 copies) zf_C2H2_10 PF18414.1 PVD20504.1 - 0.0063 16.0 0.1 0.0063 16.0 0.1 6.3 8 0 0 8 8 5 1 C2H2 type zinc-finger zf-Di19 PF05605.12 PVD20504.1 - 0.015 15.6 104.4 0.024 14.9 3.2 12.7 11 2 3 14 14 14 0 Drought induced 19 protein (Di19), zinc-binding DUF3565 PF12088.8 PVD20504.1 - 0.017 15.0 0.6 2.4 8.2 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3565) zf-CSL PF05207.13 PVD20504.1 - 0.26 11.0 12.5 5 6.9 0.3 6.0 5 0 0 5 5 5 0 CSL zinc finger PyrI_C PF02748.15 PVD20504.1 - 0.39 10.7 8.5 3.4 7.6 0.1 5.5 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4578 PF15147.6 PVD20504.1 - 2.4 9.1 13.8 1.8 9.5 0.3 3.8 3 1 1 4 4 3 0 Domain of unknown function (DUF4578) ABC1 PF03109.16 PVD20505.1 - 2.3e-35 121.3 0.0 4.3e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family AAA_32 PF13654.6 PVD20505.1 - 0.055 12.2 0.1 0.092 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 PVD20506.1 - 2.6e-25 88.8 0.1 8.2e-12 45.5 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20506.1 - 3.2e-25 88.2 0.1 1.7e-10 41.2 0.1 3.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20506.1 - 1.4e-19 68.1 0.1 0.00018 21.7 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 PVD20506.1 - 6.4e-19 67.5 1.9 0.00062 20.1 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD20506.1 - 1.7e-15 56.9 0.7 1.2e-05 25.5 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20507.1 - 3.6e-22 78.7 0.2 7.8e-11 42.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20507.1 - 7.4e-18 64.7 0.0 2.8e-10 40.5 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD20507.1 - 2e-12 47.1 0.1 0.0001 22.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 PVD20507.1 - 6.3e-12 45.8 0.2 1.1e-11 45.0 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 PVD20507.1 - 7.1e-12 45.2 0.2 6.5e-05 23.2 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD20507.1 - 2.3e-11 42.8 0.0 2.5e-05 24.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat SAM_2 PF07647.17 PVD20507.1 - 1.5e-10 41.0 0.2 3.1e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 PVD20507.1 - 0.0014 18.7 0.0 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 IGR protein motif DUF1190 PF06693.11 PVD20507.1 - 0.23 11.9 3.3 0.35 11.2 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1190) tRNA-synt_2c PF01411.19 PVD20508.1 - 9.9e-80 268.6 0.4 1.8e-77 261.2 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PVD20508.1 - 6.2e-15 55.0 0.3 1.4e-14 53.9 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 PVD20508.1 - 5.2e-12 46.4 1.3 5.2e-12 46.4 1.3 2.2 1 1 1 2 2 2 1 DHHA1 domain Baculo_PEP_C PF04513.12 PVD20508.1 - 0.042 13.9 0.3 0.14 12.2 0.3 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 PVD20508.1 - 0.53 9.1 1.0 1.6 7.5 1.1 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein GrpE PF01025.19 PVD20508.1 - 0.68 9.6 7.1 3.8 7.2 7.0 2.2 1 1 0 1 1 1 0 GrpE FA_hydroxylase PF04116.13 PVD20509.1 - 2.5e-18 66.7 11.9 4.9e-18 65.8 11.9 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 PVD20509.1 - 1.3e-14 54.0 0.3 1e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.13 PVD20509.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region TMEM189_B_dmain PF10520.9 PVD20509.1 - 1.4 9.0 9.0 0.53 10.4 0.2 3.1 2 1 1 3 3 3 0 B domain of TMEM189, localisation domain 7tm_1 PF00001.21 PVD20511.1 - 4.7e-37 127.8 1.4 3.6e-18 65.8 1.8 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD20511.1 - 0.0018 18.0 1.0 0.0038 16.9 1.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD20511.1 - 0.0035 16.8 2.2 1.1 8.5 0.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx PSDC PF12588.8 PVD20511.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase RGS PF00615.19 PVD20512.1 - 8.3e-07 29.3 1.1 0.00014 22.1 0.2 9.8 10 2 0 10 10 10 6 Regulator of G protein signaling domain RGS PF00615.19 PVD20513.1 - 2.1e-08 34.5 0.1 0.00015 22.1 0.0 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain NatB_MDM20 PF09797.9 PVD20513.1 - 0.0036 16.3 0.5 0.0071 15.3 0.5 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit RGS PF00615.19 PVD20514.1 - 9e-10 38.9 9.2 0.0081 16.4 0.0 6.1 4 2 1 5 5 5 4 Regulator of G protein signaling domain Cofilin_ADF PF00241.20 PVD20516.1 - 1.6e-16 60.2 0.0 1.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.22 PVD20517.1 - 4.5e-53 179.2 0.0 5.3e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20517.1 - 3.5e-34 117.6 0.0 5.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD20517.1 - 2.4e-09 36.9 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD20517.1 - 0.00015 21.7 0.0 0.0097 15.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 PVD20517.1 - 0.00026 21.0 0.0 0.00046 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 PVD20517.1 - 0.00065 19.1 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD20517.1 - 0.00094 19.3 0.0 0.0017 18.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD20517.1 - 0.001 18.7 0.0 0.0054 16.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 PVD20517.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PVD20517.1 - 0.034 14.5 0.0 0.042 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 PVD20517.1 - 0.039 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain G-alpha PF00503.20 PVD20517.1 - 0.055 12.6 0.0 0.38 9.9 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 PVD20517.1 - 0.055 12.9 0.0 0.088 12.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 PVD20517.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD20517.1 - 0.086 13.4 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 PVD20517.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 PVD20517.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 PVD20517.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF815 PF05673.13 PVD20517.1 - 0.16 11.1 0.0 0.57 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TED_complement PF07678.14 PVD20518.1 - 7.8e-40 136.8 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 PVD20518.1 - 2.8e-26 91.2 0.4 8.2e-26 89.7 0.4 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 PVD20518.1 - 2.7e-19 69.9 2.4 1.4e-16 61.1 0.1 3.2 2 1 0 2 2 2 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD20518.1 - 5.8e-12 45.7 0.7 2.3e-11 43.8 0.7 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD20518.1 - 3.1e-11 43.6 0.0 1.9e-10 41.0 0.0 2.5 1 0 0 1 1 1 1 MG2 domain A2M_recep PF07677.14 PVD20518.1 - 1.3e-10 41.8 0.4 4.2e-10 40.2 0.1 2.1 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG4 PF17789.1 PVD20518.1 - 0.00036 20.6 1.5 0.088 13.0 0.0 3.8 4 0 0 4 4 4 1 Macroglobulin domain MG4 B2 PF11473.8 PVD20518.1 - 0.0029 17.4 0.0 2.2 8.1 0.0 3.1 3 0 0 3 3 3 2 RNA binding protein B2 Prenyltrans PF00432.21 PVD20518.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat 7tm_1 PF00001.21 PVD20521.1 - 7.2e-20 71.4 20.7 1.1e-15 57.7 7.3 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD20521.1 - 6.3e-17 61.8 23.9 1.3e-08 34.5 8.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD20521.1 - 2.6e-10 40.4 28.0 4.2e-09 36.4 9.5 3.2 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD20521.1 - 4.3e-05 23.4 3.9 4.3e-05 23.4 3.9 2.2 2 0 0 2 2 2 1 Olfactory receptor Serpentine_r_xa PF03383.15 PVD20521.1 - 0.0016 18.4 5.1 0.0016 18.4 5.1 3.3 2 1 1 4 4 4 1 Caenorhabditis serpentine receptor-like protein, class xa DUF962 PF06127.11 PVD20521.1 - 0.035 14.2 0.7 0.035 14.2 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF1345 PF07077.11 PVD20521.1 - 1.2 8.8 8.6 5.5 6.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) Sm_multidrug_ex PF06695.11 PVD20521.1 - 9.9 6.8 8.9 0.74 10.5 0.2 3.2 4 0 0 4 4 4 0 Putative small multi-drug export protein Hormone_recep PF00104.30 PVD20522.1 - 1.3e-40 139.2 0.4 2.3e-40 138.4 0.1 1.5 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD20522.1 - 1.3e-29 102.4 18.8 2.1e-29 101.7 18.8 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4638 PF15472.6 PVD20523.1 - 0.00044 20.1 0.1 0.0024 17.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4638) DUF2408 PF10303.9 PVD20523.1 - 0.1 13.2 0.1 0.79 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) 7tm_1 PF00001.21 PVD20526.1 - 0.00036 19.9 6.3 0.0019 17.6 6.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DAG1 PF05454.11 PVD20526.1 - 0.59 9.5 2.4 1 8.7 2.4 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1279 PF06916.13 PVD20527.1 - 1.2e-24 86.6 0.6 2.4e-24 85.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Methyltrn_RNA_4 PF09936.9 PVD20527.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase RRM_1 PF00076.22 PVD20528.1 - 1.6e-17 63.0 0.2 7.7e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PA26 PF04636.13 PVD20528.1 - 0.2 10.6 0.7 0.24 10.3 0.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pes-10 PF07149.11 PVD20528.1 - 4.1 6.4 7.3 4.9 6.1 7.3 1.1 1 0 0 1 1 1 0 Pes-10 DUF3808 PF10300.9 PVD20529.1 - 0.01 14.6 1.6 0.89 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) HMW1C_N PF18071.1 PVD20529.1 - 0.042 13.7 0.3 1.5 8.6 0.3 2.8 2 0 0 2 2 2 0 HMW1C N-terminal TPR_16 PF13432.6 PVD20529.1 - 0.17 12.6 0.1 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20529.1 - 2.1 8.7 10.0 2.4 8.5 0.0 4.6 7 0 0 7 7 7 0 Tetratricopeptide repeat ORC3_N PF07034.11 PVD20531.1 - 0.0065 15.6 0.1 0.0068 15.6 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus AAA_12 PF13087.6 PVD20532.1 - 2.1e-37 128.7 0.0 5.1e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD20532.1 - 1.5e-27 97.0 2.5 3e-14 53.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PVD20532.1 - 4e-08 33.7 0.6 9.5e-06 26.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PVD20532.1 - 2.5e-06 27.4 0.0 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 PVD20532.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PVD20532.1 - 0.0032 16.8 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 PVD20532.1 - 0.0092 15.8 1.5 0.027 14.2 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD20532.1 - 0.015 15.5 2.3 2.6 8.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 PVD20532.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 PVD20532.1 - 0.54 9.7 5.4 0.34 10.4 0.1 3.0 2 2 0 2 2 2 0 UvrD/REP helicase N-terminal domain AA_permease_2 PF13520.6 PVD20533.1 - 5.9e-103 344.9 81.9 9.9e-56 189.4 47.7 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 PVD20533.1 - 1.5e-56 192.0 75.1 5.8e-32 110.9 24.1 2.3 2 0 0 2 2 2 2 Amino acid permease AAA_12 PF13087.6 PVD20533.1 - 3.3e-39 134.6 0.3 1e-38 133.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PVD20533.1 - 6.8e-27 94.9 5.5 3.6e-14 53.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PVD20533.1 - 2.1e-09 37.9 0.0 3.7e-07 30.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD20533.1 - 4.7e-07 29.7 0.0 5.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 PVD20533.1 - 0.0013 18.3 2.2 0.0023 17.5 0.0 2.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 PVD20533.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PVD20533.1 - 0.0041 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 PVD20533.1 - 0.0076 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein B12-binding PF02310.19 PVD20533.1 - 0.027 14.5 3.8 1.3 9.1 0.3 2.6 2 0 0 2 2 2 0 B12 binding domain IstB_IS21 PF01695.17 PVD20533.1 - 0.036 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_M15_2 PF05951.13 PVD20533.1 - 0.11 12.1 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Pox_Ag35 PF03286.14 PVD20533.1 - 0.14 11.9 4.3 0.41 10.4 4.3 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MinC_N PF05209.13 PVD20533.1 - 0.18 11.8 2.1 27 4.8 0.1 3.6 3 0 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain PMC2NT PF08066.12 PVD20533.1 - 4.4 8.1 5.1 11 6.8 0.0 3.6 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Lectin_C PF00059.21 PVD20534.1 - 1.3e-06 29.0 1.6 3.6e-06 27.7 1.6 1.7 1 0 0 1 1 1 1 Lectin C-type domain Ntox22 PF15527.6 PVD20534.1 - 0.013 15.6 9.1 0.05 13.7 0.7 2.5 1 1 1 2 2 2 0 Bacterial toxin 22 RRM_1 PF00076.22 PVD20535.1 - 7.4e-37 125.0 0.4 1.5e-08 34.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PVD20535.1 - 0.0069 16.4 0.1 0.097 12.8 0.0 2.7 3 0 0 3 3 3 1 Limkain b1 Raftlin PF15250.6 PVD20535.1 - 1.4 7.6 7.1 2.9 6.5 7.1 1.5 1 0 0 1 1 1 0 Raftlin Meckelin PF09773.9 PVD20536.1 - 1.7e-247 823.7 11.9 2.2e-247 823.3 11.9 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) DUF4535 PF15054.6 PVD20536.1 - 1.2e-09 37.8 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Vma12 PF11712.8 PVD20536.1 - 3.9 7.5 6.0 0.54 10.3 0.4 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FMO-like PF00743.19 PVD20537.1 - 2.8e-43 148.1 0.7 9.3e-37 126.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD20537.1 - 7.4e-11 41.8 0.0 5.3e-07 29.2 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD20537.1 - 2.2e-06 27.1 0.0 7.7e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD20537.1 - 9.3e-05 21.7 0.0 0.00039 19.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TMEM51 PF15345.6 PVD20537.1 - 0.0092 15.8 7.0 0.049 13.5 0.1 3.0 2 1 1 3 3 3 1 Transmembrane protein 51 Spectrin PF00435.21 PVD20538.1 - 0.0012 19.3 1.1 0.52 10.8 0.1 2.7 2 1 0 2 2 2 2 Spectrin repeat CRAL_TRIO_2 PF13716.6 PVD20538.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RhoGEF PF00621.20 PVD20539.1 - 3.9e-35 121.7 4.0 3.9e-35 121.7 4.0 1.8 2 0 0 2 2 2 1 RhoGEF domain IQ_SEC7_PH PF16453.5 PVD20539.1 - 0.00067 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 PH domain PH PF00169.29 PVD20539.1 - 0.00076 20.0 0.1 0.0024 18.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 PVD20539.1 - 0.039 14.2 1.3 1 9.7 1.3 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain PROL5-SMR PF15621.6 PVD20539.1 - 0.4 11.2 1.5 1.4 9.5 0.2 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family zf-CCCH_4 PF18044.1 PVD20540.1 - 7.7e-09 35.2 2.9 1.2e-08 34.6 2.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD20540.1 - 9.3e-06 25.5 4.4 1.5e-05 24.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PVD20540.1 - 0.003 17.4 1.6 0.0052 16.7 1.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PVD20540.1 - 0.0094 16.6 3.7 0.0095 16.6 0.1 2.5 2 0 0 2 2 2 1 Torus domain CTNNBL PF08216.11 PVD20541.1 - 6.6e-38 129.1 2.2 1.8e-37 127.7 2.2 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3384 PF11864.8 PVD20541.1 - 0.25 10.2 3.6 0.86 8.4 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3384) UCR_TM PF02921.14 PVD20542.1 - 2e-29 101.9 6.1 3.8e-29 101.0 6.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Ubiq-Cytc-red_N PF09165.10 PVD20542.1 - 3.9e-12 46.9 4.0 8.5e-12 45.8 4.0 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Rieske PF00355.26 PVD20542.1 - 2.5e-08 33.7 0.1 9.4e-08 31.9 0.1 2.0 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain LAP1C PF05609.12 PVD20543.1 - 0.019 14.1 8.0 0.025 13.7 8.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4576 PF15144.6 PVD20543.1 - 0.076 12.9 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) SLC12 PF03522.15 PVD20543.1 - 0.18 10.8 6.5 0.23 10.4 6.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 PVD20543.1 - 0.63 8.7 7.4 0.72 8.5 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 PVD20543.1 - 2.6 7.2 19.2 3.7 6.7 19.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) EPF PF17181.4 PVD20546.1 - 0.014 15.4 0.6 0.024 14.6 0.6 1.4 1 0 0 1 1 1 0 Epidermal patterning factor proteins zf-C2H2 PF00096.26 PVD20550.1 - 1.6e-05 25.1 49.2 0.08 13.4 0.8 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD20550.1 - 0.00046 20.5 4.7 0.011 16.2 1.6 6.6 9 0 0 9 9 9 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 PVD20550.1 - 0.0037 17.0 5.7 0.012 15.4 2.2 6.7 6 0 0 6 6 6 3 C2H2-type zinc-finger domain DUF2321 PF10083.9 PVD20550.1 - 0.019 14.6 0.4 3.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_2 PF12756.7 PVD20550.1 - 0.021 15.1 23.4 3.3 8.1 1.2 5.6 4 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 PVD20550.1 - 0.035 14.5 4.0 2.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 PVD20550.1 - 0.053 14.4 48.3 2.1 9.4 0.7 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PVD20550.1 - 0.13 12.0 20.1 6.5 6.5 0.1 6.2 6 0 0 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 PVD20550.1 - 1.1 9.9 12.1 0.54 10.9 2.5 4.1 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 PVD20550.1 - 2.3 8.6 31.7 0.18 12.1 1.4 6.2 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 PVD20551.1 - 4e-06 26.5 15.9 6e-05 22.7 1.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD20551.1 - 4.8e-06 26.8 7.3 3.8e-05 23.9 3.8 2.5 2 0 0 2 2 2 1 Zinc-finger double domain DUF3716 PF12511.8 PVD20551.1 - 0.029 14.4 2.0 0.057 13.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Rota_NS26 PF01525.16 PVD20551.1 - 0.062 13.3 0.6 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Rotavirus NS26 FAM25 PF15825.5 PVD20551.1 - 0.18 12.1 0.7 18 5.8 0.0 2.7 2 0 0 2 2 2 0 FAM25 family zf-C2H2_4 PF13894.6 PVD20551.1 - 1.4 9.9 11.0 9.1 7.4 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20551.1 - 3.5 8.3 8.9 9.2 6.9 0.8 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD20552.1 - 4.9e-11 42.2 8.4 0.0005 19.8 0.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD20552.1 - 1.8e-05 24.9 19.3 0.0058 17.0 0.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20552.1 - 0.00017 22.1 16.5 0.043 14.7 1.0 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PVD20552.1 - 0.00078 19.0 4.4 0.46 10.2 0.5 3.2 3 0 0 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 PVD20552.1 - 0.0033 17.7 8.5 0.46 10.9 0.7 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) PriA_CRR PF18319.1 PVD20552.1 - 0.01 15.8 1.1 6.3 6.9 0.0 3.6 3 0 0 3 3 3 1 PriA DNA helicase Cys-rich region (CRR) domain zf-Di19 PF05605.12 PVD20552.1 - 0.013 15.8 7.6 4 7.8 0.1 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD20552.1 - 0.062 13.1 0.1 0.062 13.1 0.1 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_2 PF03107.16 PVD20552.1 - 0.063 13.6 11.9 1 9.8 0.2 3.7 4 0 0 4 4 3 0 C1 domain Stc1 PF12898.7 PVD20552.1 - 0.075 13.6 4.2 0.17 12.4 4.2 1.7 1 0 0 1 1 1 0 Stc1 domain AKAP95 PF04988.12 PVD20552.1 - 0.087 13.1 4.3 1.4 9.1 0.1 2.8 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-HIT PF04438.16 PVD20552.1 - 0.12 12.2 8.3 0.58 10.1 0.6 3.3 3 0 0 3 3 3 0 HIT zinc finger zf-H2C2_2 PF13465.6 PVD20552.1 - 0.94 10.0 0.0 0.94 10.0 0.0 5.5 5 1 0 5 5 5 0 Zinc-finger double domain Rubredoxin_2 PF18073.1 PVD20552.1 - 1.2 9.0 11.4 23 4.8 0.8 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Actin_micro PF17003.5 PVD20552.1 - 1.2 8.2 8.2 2.3 7.3 0.1 2.9 1 1 2 3 3 3 0 Putative actin-like family OrsD PF12013.8 PVD20552.1 - 6.4 7.3 8.0 17 5.9 0.4 3.2 2 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 PVD20552.1 - 8.8 6.4 9.4 0.25 11.4 0.8 2.8 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.6 PVD20553.1 - 2.6e-13 49.5 86.2 1.3e-05 24.8 1.1 10.3 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD20553.1 - 1.7e-06 28.2 84.6 0.022 15.2 0.2 10.1 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20553.1 - 0.00018 22.1 78.7 0.58 11.1 1.2 10.7 10 0 0 10 10 10 6 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PVD20553.1 - 0.00041 19.9 0.5 0.00041 19.9 0.5 9.6 8 2 2 10 10 10 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 PVD20553.1 - 0.018 15.4 3.2 0.018 15.4 3.2 11.1 14 0 0 14 14 14 0 Zinc-finger double domain ATC_hydrolase PF14196.6 PVD20553.1 - 0.019 15.7 0.1 0.088 13.6 0.1 2.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase I-EGF_1 PF18372.1 PVD20553.1 - 8.8 6.5 9.8 6.5 6.9 0.6 3.2 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 HECT PF00632.25 PVD20554.1 - 2.6e-98 329.3 0.2 3.4e-98 328.9 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 PVD20554.1 - 1.5e-50 168.9 24.3 9.4e-14 51.2 2.7 4.7 4 0 0 4 4 4 4 WW domain C2 PF00168.30 PVD20554.1 - 1.5e-14 54.1 0.0 3.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Neil1-DNA_bind PF09292.10 PVD20554.1 - 4.1 7.4 5.6 3.5 7.7 0.1 3.7 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind PIN_6 PF17146.4 PVD20555.1 - 2e-30 105.1 0.0 4.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 PVD20555.1 - 9.3e-22 77.0 0.7 2.6e-21 75.6 0.7 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like WRNPLPNID PF15017.6 PVD20555.1 - 0.0083 17.0 9.8 0.042 14.7 9.7 2.2 1 1 0 1 1 1 1 Putative WW-binding domain and destruction box DUF1214 PF06742.11 PVD20555.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) Cys_rich_KTR PF14205.6 PVD20555.1 - 0.2 11.5 0.2 0.2 11.5 0.2 2.4 2 1 1 3 3 3 0 Cysteine-rich KTR PX PF00787.24 PVD20556.1 - 5.2e-13 49.0 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 PVD20557.1 - 2e-11 43.5 0.1 3.9e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon PF03129.20 PVD20557.1 - 8e-06 25.9 0.2 1.4e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain RRM_5 PF13893.6 PVD20557.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SapB_2 PF03489.17 PVD20558.1 - 6.9e-08 32.5 0.0 1.9e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 Lipase_GDSL PF00657.22 PVD20558.1 - 3.8e-05 23.8 0.0 0.00015 21.8 0.0 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 PVD20558.1 - 0.00083 19.5 2.5 0.00083 19.5 2.5 2.7 3 0 0 3 3 3 1 Putative metal-binding motif Lipase_GDSL_2 PF13472.6 PVD20558.1 - 0.077 13.4 0.2 0.21 12.0 0.2 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ASH PF15780.5 PVD20559.1 - 1.2e-11 44.6 0.5 0.018 15.2 0.0 7.3 6 1 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MYCBPAP PF14646.6 PVD20559.1 - 1.2e-07 31.1 0.2 1.8e-05 23.9 0.0 3.7 4 1 0 4 4 4 1 MYCBP-associated protein family Motile_Sperm PF00635.26 PVD20559.1 - 1.5e-07 31.2 0.4 2.7 7.9 0.1 5.1 4 1 0 4 4 4 4 MSP (Major sperm protein) domain RSB_motif PF16294.5 PVD20562.1 - 2.5e-24 85.5 20.2 2.5e-24 85.5 20.2 16.9 6 5 9 15 15 15 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 PVD20562.1 - 2.2e-07 30.4 4.2 2.9e-07 30.1 2.6 2.1 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 PVD20562.1 - 0.00026 20.8 0.0 0.00062 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS9 PF02204.18 PVD20563.1 - 7.9e-16 58.2 0.0 2.7e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Arf PF00025.21 PVD20564.1 - 8.4e-99 328.2 2.5 1.1e-55 187.8 0.0 4.3 3 1 0 3 3 3 3 ADP-ribosylation factor family Transglut_N PF00868.20 PVD20564.1 - 8.5e-30 103.5 0.1 2.7e-29 101.9 0.1 1.9 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 PVD20564.1 - 1.2e-16 60.7 0.1 5.4e-11 42.6 0.1 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 PVD20564.1 - 1.6e-13 51.1 0.4 3.6e-13 49.9 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Roc PF08477.13 PVD20564.1 - 9.1e-12 45.3 0.1 8.8e-08 32.4 0.0 3.1 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD20564.1 - 1.6e-10 40.9 0.1 3.2e-07 30.1 0.0 3.4 2 1 1 3 3 3 1 Ras family SRPRB PF09439.10 PVD20564.1 - 1.1e-09 38.0 0.0 1.3e-05 24.7 0.0 3.2 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD20564.1 - 9.2e-09 34.9 0.0 1.8e-07 30.7 0.0 2.6 2 1 1 3 3 3 1 G-protein alpha subunit Gtr1_RagA PF04670.12 PVD20564.1 - 6.4e-08 32.2 0.0 5.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GramPos_pilinD1 PF16555.5 PVD20564.1 - 0.075 13.2 0.0 9 6.5 0.0 2.5 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Ribonuclease_T2 PF00445.18 PVD20564.1 - 0.17 12.1 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease T2 family DUF3913 PF13052.6 PVD20564.1 - 1.6 9.0 5.1 26 5.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) Sporozoite_P67 PF05642.11 PVD20565.1 - 0.12 10.4 5.5 0.14 10.2 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 PVD20565.1 - 0.38 9.0 14.5 0.41 8.9 14.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 PVD20565.1 - 1.2 9.2 14.1 1.6 8.7 14.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal XAP5 PF04921.14 PVD20565.1 - 4 7.2 17.5 5.6 6.7 17.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DNA_pol_phi PF04931.13 PVD20565.1 - 5.8 4.9 20.9 7.2 4.6 20.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 PVD20565.1 - 6.9 7.0 19.4 12 6.1 19.4 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_fiss_reg PF05308.11 PVD20566.1 - 0.83 9.7 7.6 1.1 9.3 7.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TAFH PF07531.14 PVD20567.1 - 3.6e-34 116.7 1.6 8.1e-34 115.6 1.6 1.6 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.11 PVD20567.1 - 3.3e-19 68.4 2.5 1e-18 66.8 2.5 1.8 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 PVD20567.1 - 1e-07 31.9 14.9 1.9e-07 31.1 14.9 1.5 1 0 0 1 1 1 1 MYND finger CI-B14_5a PF07347.12 PVD20567.1 - 0.1 12.5 1.9 0.93 9.4 0.1 2.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF3731 PF12531.8 PVD20567.1 - 0.25 11.1 7.2 8.9 6.0 7.2 2.3 1 1 0 1 1 1 0 DNA-K related protein Mucin PF01456.17 PVD20567.1 - 0.28 11.2 16.2 0.69 9.9 16.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein HscB_4_cys PF18256.1 PVD20567.1 - 5.3 6.9 6.6 18 5.3 6.6 1.9 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Orthopox_A5L PF06193.11 PVD20567.1 - 5.7 6.3 14.2 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Glyco_hydro_16 PF00722.21 PVD20568.1 - 2.7e-16 59.6 1.8 1.5e-15 57.1 1.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2341 PF10102.9 PVD20568.1 - 0.021 15.4 0.1 0.073 13.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) HtrL_YibB PF09612.10 PVD20569.1 - 7.6e-14 51.9 2.4 1.5e-13 50.9 2.4 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Methyltransf_22 PF13383.6 PVD20570.1 - 2.2e-19 70.0 0.5 2.9e-19 69.6 0.5 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20570.1 - 3.7e-06 27.1 0.0 5.1e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20570.1 - 0.044 14.0 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_16 PF00722.21 PVD20571.1 - 1.3e-16 60.6 1.9 2.8e-16 59.5 1.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2341 PF10102.9 PVD20571.1 - 0.026 15.1 0.1 0.09 13.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) Glyco_hydro_16 PF00722.21 PVD20572.1 - 3.7e-16 59.1 2.8 2.1e-15 56.6 2.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2341 PF10102.9 PVD20572.1 - 0.021 15.4 0.1 0.089 13.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF3689 PF12463.8 PVD20573.1 - 0.059 12.7 0.3 0.065 12.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) CD225 PF04505.12 PVD20574.1 - 1.1e-06 28.6 10.0 2.5e-05 24.3 1.5 2.3 2 0 0 2 2 2 2 Interferon-induced transmembrane protein zf-CHC2 PF01807.20 PVD20574.1 - 0.0044 16.8 1.5 4.6 7.1 0.2 3.0 3 0 0 3 3 3 2 CHC2 zinc finger DUF4190 PF13828.6 PVD20574.1 - 0.0047 16.6 0.1 0.0047 16.6 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4190) P5-ATPase PF12409.8 PVD20574.1 - 3.8 7.6 5.4 0.66 10.1 0.3 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter CD225 PF04505.12 PVD20575.1 - 1.6e-05 24.9 2.8 3e-05 24.1 2.8 1.4 1 1 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 PVD20575.1 - 0.00048 19.8 0.4 0.00048 19.8 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4190) FtsX PF02687.21 PVD20575.1 - 0.022 15.2 5.8 0.03 14.8 5.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family Comm PF15957.5 PVD20575.1 - 0.027 14.8 1.4 0.027 14.8 1.4 1.8 2 1 0 2 2 2 0 Commissureless DUF4203 PF13886.6 PVD20575.1 - 0.031 14.0 8.2 0.038 13.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) P5-ATPase PF12409.8 PVD20575.1 - 0.17 12.0 0.4 0.17 12.0 0.4 1.8 2 0 0 2 2 2 0 P5-type ATPase cation transporter Glyco_transf_11 PF01531.16 PVD20576.1 - 7.8e-37 127.1 0.1 1e-36 126.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD20576.1 - 8.7e-05 22.4 0.1 0.0002 21.2 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Branch PF02485.21 PVD20577.1 - 7.3e-38 130.5 0.1 2.4e-37 128.8 0.0 1.9 2 1 0 2 2 2 1 Core-2/I-Branching enzyme Nup84_Nup100 PF04121.13 PVD20577.1 - 0.025 12.7 0.0 0.03 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Exo_endo_phos_2 PF14529.6 PVD20578.1 - 8.3e-09 35.3 0.2 2.2e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD20578.1 - 6e-08 32.5 0.1 1.1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1104 PF06518.11 PVD20578.1 - 8.8 6.8 17.2 3.4 8.1 6.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) Glyco_transf_11 PF01531.16 PVD20579.1 - 1.9e-38 132.4 0.3 2.4e-38 132.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD20579.1 - 8.7e-05 22.4 0.6 0.0002 21.2 0.5 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Methyltransf_22 PF13383.6 PVD20580.1 - 7e-18 65.1 0.2 8.9e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20580.1 - 2e-05 24.7 0.0 2.9e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20580.1 - 0.041 14.1 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD20581.1 - 7.5e-19 68.3 0.1 9.6e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD20581.1 - 8e-06 26.0 0.0 1.1e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD20581.1 - 0.042 14.1 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Branch PF02485.21 PVD20582.1 - 5.8e-38 130.8 0.0 7.9e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme CD225 PF04505.12 PVD20583.1 - 0.00018 21.6 2.8 0.00029 20.9 2.2 1.7 1 1 0 1 1 1 1 Interferon-induced transmembrane protein Comm PF15957.5 PVD20583.1 - 0.038 14.3 2.6 0.045 14.1 1.2 1.8 1 1 1 2 2 2 0 Commissureless DUF4190 PF13828.6 PVD20583.1 - 0.55 10.0 8.2 0.11 12.3 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) CD225 PF04505.12 PVD20584.1 - 5.7e-12 45.6 26.3 0.00073 19.6 6.8 3.3 3 0 0 3 3 3 3 Interferon-induced transmembrane protein Comm PF15957.5 PVD20584.1 - 9.8e-08 32.4 21.4 0.00088 19.6 0.0 4.0 3 1 0 3 3 3 2 Commissureless P5-ATPase PF12409.8 PVD20584.1 - 0.0033 17.5 9.2 2.3 8.3 0.4 3.4 3 0 0 3 3 3 3 P5-type ATPase cation transporter DUF4190 PF13828.6 PVD20584.1 - 0.095 12.5 0.4 0.095 12.5 0.4 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4190) Vma12 PF11712.8 PVD20584.1 - 0.12 12.5 7.6 5.2 7.1 0.3 3.3 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4231 PF14015.6 PVD20584.1 - 0.76 10.3 4.1 3.8 8.0 0.2 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF4231) Ninjurin PF04923.12 PVD20584.1 - 1.1 9.2 8.5 7.5 6.6 1.2 3.2 3 0 0 3 3 3 0 Ninjurin DUF1673 PF07895.11 PVD20584.1 - 1.5 8.5 10.5 7.7 6.2 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) AIRC PF00731.20 PVD20584.1 - 1.6 8.3 8.8 7 6.2 0.2 3.2 3 0 0 3 3 3 0 AIR carboxylase Heliorhodopsin PF18761.1 PVD20584.1 - 3.7 6.8 14.8 0.081 12.2 1.4 2.6 3 0 0 3 3 3 0 Heliorhodopsin FtsX PF02687.21 PVD20584.1 - 4 8.0 24.0 7.6 7.1 8.2 3.0 3 0 0 3 3 3 0 FtsX-like permease family CD225 PF04505.12 PVD20586.1 - 7.1e-16 58.1 25.0 3e-05 24.1 2.3 3.7 3 0 0 3 3 3 3 Interferon-induced transmembrane protein ECF_trnsprt PF12822.7 PVD20586.1 - 8.3e-05 22.7 14.6 0.0012 19.0 3.0 2.6 1 1 1 2 2 2 1 ECF transporter, substrate-specific component DUF4203 PF13886.6 PVD20586.1 - 0.0016 18.1 40.9 0.24 11.0 7.2 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4203) P5-ATPase PF12409.8 PVD20586.1 - 0.009 16.1 17.5 2 8.5 1.2 3.6 3 0 0 3 3 3 3 P5-type ATPase cation transporter DUF4010 PF13194.6 PVD20586.1 - 0.062 13.0 10.6 0.93 9.1 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) Rhomboid PF01694.22 PVD20586.1 - 0.2 11.6 22.7 2.2 8.3 1.9 3.2 3 0 0 3 3 3 0 Rhomboid family Comm PF15957.5 PVD20586.1 - 0.63 10.4 34.7 0.87 10.0 2.2 5.2 3 3 1 4 4 4 0 Commissureless DUF4834 PF16118.5 PVD20586.1 - 1.9 9.5 9.6 47 5.0 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Ost4 PF10215.9 PVD20586.1 - 2.2 8.2 27.1 2.4 8.1 5.0 3.7 3 0 0 3 3 3 0 Oligosaccaryltransferase Peptidase_C41 PF05417.11 PVD20586.1 - 4.3 7.1 8.7 3.3 7.5 0.1 2.9 3 0 0 3 3 3 0 Hepatitis E cysteine protease COesterase PF00135.28 PVD20587.1 - 1.6e-148 495.8 0.0 2e-148 495.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD20587.1 - 0.00016 21.6 0.0 0.00047 20.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD20588.1 - 9.1e-156 519.7 0.0 1e-155 519.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD20588.1 - 1.1e-05 25.4 0.1 3.1e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Kringle PF00051.18 PVD20589.1 - 5.4e-30 103.5 8.9 2.3e-17 63.0 1.1 2.7 2 1 0 2 2 2 2 Kringle domain Sushi PF00084.20 PVD20589.1 - 0.00014 22.4 0.1 0.00045 20.7 0.1 2.0 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) zf-C2H2 PF00096.26 PVD20590.1 - 6.1e-39 130.3 67.2 0.00018 21.8 1.0 10.9 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20590.1 - 1.1e-34 116.1 64.9 0.00082 20.0 0.2 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD20590.1 - 9.7e-23 79.5 58.9 7.3e-06 26.2 0.4 12.0 12 1 0 12 12 11 5 Zinc-finger double domain zf-met PF12874.7 PVD20590.1 - 1.3e-20 73.0 45.0 0.0013 19.1 0.6 10.0 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD20590.1 - 1.1e-11 44.4 62.0 0.0031 17.5 0.7 10.1 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD20590.1 - 2.2e-07 31.0 52.2 0.14 12.5 2.2 10.6 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding BolA PF01722.18 PVD20590.1 - 0.00014 22.1 2.1 2.1 8.7 0.2 5.2 2 2 0 2 2 2 1 BolA-like protein Zn-ribbon_8 PF09723.10 PVD20590.1 - 0.022 14.9 38.5 0.42 10.8 2.0 7.5 6 5 1 7 7 7 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 PVD20590.1 - 0.028 14.7 35.9 2.6 8.4 1.7 5.8 3 2 3 6 6 6 0 C2H2-type zinc ribbon zf-BED PF02892.15 PVD20590.1 - 0.15 12.1 0.3 0.15 12.1 0.3 9.2 5 2 4 9 9 9 0 BED zinc finger C1_2 PF03107.16 PVD20590.1 - 9.9 6.6 59.6 0.37 11.2 3.2 10.1 5 3 3 9 9 9 0 C1 domain RNA_pol_A_bac PF01000.26 PVD20591.1 - 4.4e-22 78.6 0.0 6.6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PVD20591.1 - 1.9e-07 30.4 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CREPT PF16566.5 PVD20592.1 - 3.1e-58 196.1 0.6 8.8e-58 194.7 0.6 1.8 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 PVD20592.1 - 8.3e-22 77.8 0.0 2.7e-21 76.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4351 PF14261.6 PVD20592.1 - 0.11 12.6 0.4 3.5 7.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DUF4056 PF13265.6 PVD20592.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Syntaxin_2 PF14523.6 PVD20592.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.9 4 0 0 4 4 4 0 Syntaxin-like protein Swi5 PF07061.11 PVD20592.1 - 0.21 11.7 1.9 1.5 9.0 0.0 3.0 1 1 1 2 2 2 0 Swi5 HAUS-augmin3 PF14932.6 PVD20592.1 - 0.25 10.9 3.8 0.4 10.2 3.1 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2203 PF09969.9 PVD20592.1 - 1.2 9.9 4.3 15 6.4 2.8 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DnaJ PF00226.31 PVD20593.1 - 5e-25 87.4 0.5 8e-25 86.7 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 PVD20593.1 - 5e-13 49.4 0.1 3.4e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 DnaJ C terminal domain zf-H2C2_5 PF13909.6 PVD20594.1 - 1.5e-36 123.8 236.9 4.2e-10 39.2 1.1 28.8 30 0 0 30 30 30 21 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD20594.1 - 0.0001 22.5 2.2 0.0001 22.5 2.2 34.4 38 1 0 38 38 38 12 Zinc-finger double domain zf-C2H2 PF00096.26 PVD20594.1 - 0.00018 21.8 266.2 0.0012 19.1 1.3 30.0 31 0 0 31 31 31 15 Zinc finger, C2H2 type zf-Di19 PF05605.12 PVD20594.1 - 0.0025 18.1 3.8 0.0025 18.1 3.8 17.7 16 2 2 18 18 18 6 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PVD20594.1 - 0.0064 16.8 0.2 0.0064 16.8 0.2 11.7 12 0 0 12 12 12 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD20594.1 - 0.0066 17.2 249.5 0.082 13.8 0.2 30.4 30 0 0 30 30 30 15 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD20594.1 - 0.023 14.7 0.1 0.023 14.7 0.1 15.3 19 0 0 19 19 19 0 C2H2-type zinc finger Ras PF00071.22 PVD20595.1 - 3.5e-30 104.7 0.1 4.2e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20595.1 - 1.1e-22 80.5 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PVD20595.1 - 7.7e-08 32.4 0.0 1.4e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 PVD20595.1 - 4.9e-07 29.4 0.1 5.1e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD20595.1 - 0.00031 20.2 0.1 0.00052 19.4 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PVD20595.1 - 0.00071 19.5 0.1 0.0082 16.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 PVD20595.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 PVD20595.1 - 0.033 13.5 0.3 0.056 12.7 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 PVD20595.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD20595.1 - 0.045 14.0 0.0 0.067 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD20595.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PVD20595.1 - 0.065 13.2 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 PVD20595.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 PVD20595.1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PP2C PF00481.21 PVD20596.1 - 4.9e-38 131.2 0.0 5.1e-36 124.6 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.22 PVD20597.1 - 4.6e-40 135.3 0.0 2.9e-24 84.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PVD20597.1 - 1.2e-23 84.0 0.0 2.7e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 PVD20597.1 - 1e-05 25.3 0.0 0.0055 16.5 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PVD20597.1 - 0.0061 16.5 0.0 0.093 12.8 0.0 2.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif SLC12 PF03522.15 PVD20597.1 - 0.28 10.2 6.8 0.38 9.7 6.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 PVD20597.1 - 0.97 8.2 12.2 1.3 7.8 12.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 PVD20597.1 - 2.4 7.3 5.1 3.4 6.8 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PVD20597.1 - 7.6 5.2 14.5 11 4.7 14.5 1.1 1 0 0 1 1 1 0 Presenilin TTL PF03133.15 PVD20598.1 - 2.5e-53 181.1 2.5 1.3e-33 116.4 0.8 2.0 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD20598.1 - 2.4e-08 33.6 0.1 0.0046 16.3 0.0 2.6 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD20598.1 - 4.8e-07 29.3 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Sulfatase PF00884.23 PVD20599.1 - 5.9e-58 196.7 0.1 7.1e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 PVD20599.1 - 2.3e-09 38.0 0.2 4e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 PVD20599.1 - 5e-08 32.9 0.2 2.9e-07 30.4 0.2 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 PVD20599.1 - 0.002 16.8 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Amidase_2 PF01510.25 PVD20600.1 - 9.6e-21 74.5 1.0 1.3e-20 74.1 1.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PhoLip_ATPase_C PF16212.5 PVD20602.1 - 9.3e-26 91.1 23.8 1.3e-14 54.6 19.1 3.4 3 1 1 4 4 4 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PVD20602.1 - 4.1e-18 64.8 1.3 1.2e-17 63.4 1.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PVD20602.1 - 1.5e-15 58.1 0.0 2.5e-08 34.5 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PVD20602.1 - 2.2e-12 46.9 0.0 2.2e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PVD20602.1 - 9.2e-10 38.5 0.0 2.9e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PVD20602.1 - 0.00056 19.7 0.3 0.0029 17.4 0.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 PVD20602.1 - 0.08 12.4 0.5 0.36 10.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) AA_permease_2 PF13520.6 PVD20603.1 - 1e-90 304.6 63.3 2.7e-41 141.8 22.9 3.1 2 1 1 3 3 3 3 Amino acid permease AA_permease PF00324.21 PVD20603.1 - 5.7e-63 213.2 65.0 3.5e-28 98.4 22.4 3.1 2 1 1 3 3 3 3 Amino acid permease ARL2_Bind_BART PF11527.8 PVD20603.1 - 9.2e-29 99.9 6.0 1.4e-28 99.4 6.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF3566 PF12089.8 PVD20603.1 - 0.16 12.3 15.6 0.87 10.0 0.6 5.2 3 1 1 4 4 4 0 Transmembrane domain of unknown function (DUF3566) HEAT PF02985.22 PVD20606.1 - 1.1e-23 81.2 13.7 0.0017 18.4 0.0 9.0 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.6 PVD20606.1 - 7.4e-08 32.7 0.4 1.8 9.0 0.0 6.1 3 2 4 7 7 7 4 HEAT repeats Cnd1 PF12717.7 PVD20606.1 - 2.5e-05 24.4 2.3 0.12 12.4 0.1 4.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 WRNPLPNID PF15017.6 PVD20606.1 - 2.7e-05 25.0 0.0 0.0001 23.1 0.0 2.1 1 0 0 1 1 1 1 Putative WW-binding domain and destruction box SPRY PF00622.28 PVD20608.1 - 4.4e-19 68.8 0.0 7.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 PVD20608.1 - 1.2e-11 44.3 7.1 1.2e-11 44.3 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD20608.1 - 2.2e-05 24.2 7.0 7.6e-05 22.5 7.0 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD20608.1 - 0.00054 19.7 9.7 0.0023 17.7 9.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD20608.1 - 0.00082 19.7 8.4 0.00082 19.7 8.4 2.6 3 0 0 3 3 3 1 Ring finger domain Cript PF10235.9 PVD20608.1 - 0.084 13.5 0.6 0.31 11.6 0.6 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-C2H2_4 PF13894.6 PVD20609.1 - 1.5e-05 25.4 58.1 0.0064 17.2 0.7 9.8 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20609.1 - 0.041 14.3 59.6 0.58 10.7 1.5 9.7 10 0 0 10 10 10 0 Zinc finger, C2H2 type GAGA PF09237.11 PVD20609.1 - 0.057 13.2 1.3 34 4.3 0.0 4.3 4 0 0 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.7 PVD20609.1 - 0.057 13.7 0.4 0.057 13.7 0.4 6.6 4 3 2 6 6 6 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.14 PVD20609.1 - 0.23 11.7 12.0 2.7 8.2 5.1 3.7 3 1 0 3 3 3 0 PHF5-like protein zf-MYST PF17772.1 PVD20609.1 - 2.4 7.8 8.7 5.5 6.7 0.1 4.2 4 0 0 4 4 4 0 MYST family zinc finger domain DUF4187 PF13821.6 PVD20609.1 - 3.3 7.6 5.3 12 5.7 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4187) THAP PF05485.12 PVD20610.1 - 0.00014 22.7 0.0 0.00021 22.2 0.0 1.3 1 0 0 1 1 1 1 THAP domain DUF4604 PF15377.6 PVD20611.1 - 4.3e-17 63.1 15.7 9.4e-17 62.0 15.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Tnp_P_element PF12017.8 PVD20611.1 - 2.8e-06 26.9 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Transposase protein Cdh1_DBD_1 PF18196.1 PVD20611.1 - 5 7.5 10.4 3.3 8.0 5.7 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Hydin_ADK PF17213.3 PVD20612.1 - 1e-64 218.5 1.0 1e-64 218.5 1.0 5.3 5 1 0 6 6 6 1 Hydin Adenylate kinase-like domain ASH PF15780.5 PVD20612.1 - 3.3e-48 161.9 41.5 4.2e-05 23.7 0.0 26.1 29 0 0 29 29 29 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PVD20612.1 - 1.1e-16 60.9 8.8 0.031 14.4 0.0 12.8 15 0 0 15 15 15 3 Flagellar-associated PapD-like DUF1573 PF07610.11 PVD20612.1 - 1.3e-13 50.8 0.0 0.79 9.8 0.0 14.2 16 0 0 16 16 16 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 PVD20612.1 - 1.3e-11 44.4 21.9 12 5.8 0.0 17.3 20 1 0 20 20 20 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 PVD20612.1 - 0.00017 21.8 14.1 2.8 8.3 0.0 11.5 13 0 0 13 13 13 1 Transmembrane protein 131-like ADK PF00406.22 PVD20612.1 - 0.013 15.6 0.9 5.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Adenylate kinase AAA_16 PF13191.6 PVD20612.1 - 0.22 11.9 2.8 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PVD20612.1 - 0.39 11.3 0.0 0.39 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain PRELI PF04707.14 PVD20613.1 - 1.9e-28 99.3 0.3 3e-28 98.6 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family DUF4472 PF14739.6 PVD20613.1 - 0.037 14.7 0.3 0.069 13.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Glyco_tranf_2_4 PF13704.6 PVD20613.1 - 0.064 13.8 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ank_2 PF12796.7 PVD20614.1 - 5.5e-31 107.0 2.3 6.2e-13 49.2 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20614.1 - 1.5e-20 73.3 5.9 5.3e-07 30.1 0.6 5.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20614.1 - 4.8e-18 63.4 6.3 0.00042 20.5 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD20614.1 - 9.1e-16 57.7 3.2 0.0003 21.0 0.1 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD20614.1 - 3.7e-11 43.0 1.6 0.0084 16.5 0.5 6.0 5 1 0 5 5 5 2 Ankyrin repeat SOCS_box PF07525.16 PVD20614.1 - 3.1e-08 33.8 1.4 3.1e-08 33.8 1.4 2.1 2 0 0 2 2 2 1 SOCS box IRS PF02174.17 PVD20615.1 - 1.5e-10 40.8 0.0 3.9e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 PTB domain (IRS-1 type) DUF956 PF06115.11 PVD20615.1 - 0.034 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) MARVEL PF01284.23 PVD20616.1 - 1.5e-07 31.5 23.7 4.3e-07 30.0 23.7 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 PVD20616.1 - 5.1 7.6 10.6 9.6 6.7 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) MARVEL PF01284.23 PVD20617.1 - 2.3e-06 27.7 17.9 4e-06 26.9 17.9 1.4 1 0 0 1 1 1 1 Membrane-associating domain Flo11 PF10182.9 PVD20617.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Flo11 domain MARVEL PF01284.23 PVD20618.1 - 8.4e-12 45.3 19.9 1.2e-11 44.8 19.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4328 PF14219.6 PVD20618.1 - 0.065 12.8 0.8 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DUF2417 PF10329.9 PVD20618.1 - 1.3 8.3 10.1 1.9 7.9 10.1 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) HtrL_YibB PF09612.10 PVD20619.1 - 1.7e-12 47.4 1.9 4.6e-12 46.0 1.9 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) HtrL_YibB PF09612.10 PVD20620.1 - 1.6e-12 47.6 3.0 3.1e-12 46.6 3.0 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) CAP PF00188.26 PVD20621.1 - 2.3e-23 83.4 2.6 3e-23 83.0 2.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ets PF00178.22 PVD20624.1 - 1.4e-08 35.0 0.0 1.6e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ets-domain SelP_N PF04592.14 PVD20625.1 - 0.59 9.5 6.3 0.68 9.3 6.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_hyd_65N_2 PF14498.6 PVD20626.1 - 0.028 14.3 0.3 0.043 13.7 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CD225 PF04505.12 PVD20626.1 - 0.094 12.9 1.7 0.19 11.9 1.7 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF3488 PF11992.8 PVD20626.1 - 0.73 8.7 2.2 1.1 8.1 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) PMP1_2 PF08114.11 PVD20626.1 - 6.6 6.6 6.7 4.4 7.1 1.7 2.4 2 0 0 2 2 2 0 ATPase proteolipid family Forkhead PF00250.18 PVD20627.1 - 1.2e-13 51.1 0.1 1.7e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Forkhead domain 7tm_1 PF00001.21 PVD20630.1 - 6.6e-15 55.1 16.1 4.3e-14 52.5 16.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UL42 PF17638.2 PVD20630.1 - 0.057 13.4 2.3 0.28 11.2 2.3 2.2 1 0 0 1 1 1 0 HCMV UL42 Orexin_rec2 PF03827.13 PVD20631.1 - 0.025 14.6 0.2 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 Orexin receptor type 2 Forkhead PF00250.18 PVD20632.1 - 9.5e-27 93.1 0.9 1.5e-26 92.4 0.2 1.6 2 0 0 2 2 2 1 Forkhead domain 7tm_1 PF00001.21 PVD20638.1 - 3e-25 89.0 1.5 3.8e-25 88.7 1.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Med13_C PF06333.12 PVD20638.1 - 0.062 12.6 3.0 0.091 12.0 3.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain 7tm_1 PF00001.21 PVD20639.1 - 2.6e-25 89.2 1.2 3.3e-25 88.9 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MASE1 PF05231.14 PVD20639.1 - 0.13 11.4 8.9 0.029 13.5 4.7 1.9 2 0 0 2 2 2 0 MASE1 Serpentine_r_xa PF03383.15 PVD20639.1 - 1.6 8.7 6.7 0.19 11.7 0.4 2.5 2 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 PVD20640.1 - 1.6e-05 24.4 2.3 3.1e-05 23.5 2.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pyocin_S PF06958.12 PVD20640.1 - 2.9 8.4 11.7 4.8 7.7 2.6 2.5 1 1 1 2 2 2 0 S-type Pyocin Forkhead PF00250.18 PVD20643.1 - 2e-40 137.0 0.0 3.5e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain GDP_Man_Dehyd PF16363.5 PVD20644.1 - 7.4e-162 538.4 0.1 8.4e-162 538.2 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD20644.1 - 1.1e-76 257.6 0.1 1.3e-76 257.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PVD20644.1 - 7.2e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PVD20644.1 - 5.7e-05 22.4 0.0 0.00026 20.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 PVD20644.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family SAM_1 PF00536.30 PVD20645.1 - 1.8e-15 57.1 0.5 6e-07 29.8 0.0 2.7 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD20645.1 - 3.8e-14 52.5 0.3 8.4e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 SAM domain (Sterile alpha motif) Asp_protease_2 PF13650.6 PVD20645.1 - 0.00031 21.3 0.0 0.00074 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease NCD1 PF04904.13 PVD20645.1 - 0.021 14.8 0.1 0.075 13.0 0.0 2.0 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) gag-asp_proteas PF13975.6 PVD20645.1 - 0.027 15.0 0.2 0.074 13.6 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Spuma_A9PTase PF03539.14 PVD20645.1 - 0.028 14.6 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) zf-A20 PF01754.16 PVD20645.1 - 0.12 12.3 0.3 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 A20-like zinc finger SET PF00856.28 PVD20646.1 - 1.2e-11 45.3 0.8 3.9e-10 40.4 0.1 2.7 2 1 0 2 2 2 1 SET domain TPR_16 PF13432.6 PVD20646.1 - 4.8e-08 33.5 5.0 0.00064 20.3 1.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD20646.1 - 1.2e-07 31.9 6.2 0.021 15.6 0.4 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD20646.1 - 1.9e-07 30.6 5.8 0.058 13.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20646.1 - 5.8e-07 29.1 8.7 0.26 11.5 0.9 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat zf-MYND PF01753.18 PVD20646.1 - 2.4e-05 24.3 6.0 2.4e-05 24.3 6.0 2.2 2 0 0 2 2 2 1 MYND finger TPR_19 PF14559.6 PVD20646.1 - 0.00013 22.4 3.5 0.22 12.0 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD20646.1 - 0.00017 21.6 1.2 0.052 13.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD20646.1 - 0.00043 20.4 3.6 0.074 13.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD20646.1 - 0.00053 20.2 4.0 0.017 15.3 0.4 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SAF PF08666.12 PVD20646.1 - 0.0056 17.3 0.0 3 8.5 0.0 2.4 2 0 0 2 2 2 1 SAF domain BTAD PF03704.17 PVD20646.1 - 0.024 15.0 4.3 0.35 11.3 1.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF2853 PF11015.8 PVD20646.1 - 0.084 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) TPR_12 PF13424.6 PVD20646.1 - 0.093 13.0 4.5 6.4 7.1 0.4 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD20646.1 - 0.12 12.4 0.4 1.8 8.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 PVD20646.1 - 0.17 11.1 4.4 0.5 9.5 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD20646.1 - 0.5 11.1 2.0 1.2e+02 3.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 PVD20647.1 - 8e-06 25.5 0.0 2.4e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GST_C_2 PF13410.6 PVD20647.1 - 2.5e-05 24.2 0.0 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PVD20647.1 - 0.002 18.7 0.0 0.029 15.0 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD20647.1 - 0.023 14.9 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thymopoietin PF08198.11 PVD20647.1 - 0.12 11.9 1.2 34 4.1 0.1 3.8 4 0 0 4 4 4 0 Thymopoietin protein Aminotran_1_2 PF00155.21 PVD20648.1 - 4.5e-63 213.6 0.0 2.2e-51 175.1 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PVD20648.1 - 2.1e-05 24.0 0.0 4.4e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 PVD20648.1 - 2.1e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PVD20648.1 - 0.001 18.5 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 PVD20648.1 - 0.0028 16.5 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 PVD20648.1 - 0.003 16.2 0.0 0.0043 15.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CBS PF00571.28 PVD20648.1 - 0.067 13.6 0.0 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 CBS domain XPG_I PF00867.18 PVD20649.1 - 7.6e-32 109.5 0.0 2.3e-31 108.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PVD20649.1 - 1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 PVD20649.1 - 3.3e-07 30.8 0.1 1.2e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 PVD20649.1 - 0.035 14.7 0.0 0.099 13.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4100 PF13352.6 PVD20649.1 - 6.7 6.4 12.0 0.073 12.8 2.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4100) DEAD PF00270.29 PVD20650.1 - 4.1e-47 160.2 0.0 1.1e-46 158.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD20650.1 - 2.6e-28 98.6 1.4 3.4e-27 95.0 0.1 3.2 5 0 0 5 5 5 1 Helicase conserved C-terminal domain UTP25 PF06862.12 PVD20650.1 - 7.4e-06 25.0 0.7 0.0056 15.5 0.0 3.2 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 PVD20650.1 - 0.0031 17.8 0.1 0.041 14.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 PVD20650.1 - 0.058 13.1 2.1 0.38 10.5 0.0 3.1 3 1 1 4 4 4 0 Phosphoribulokinase / Uridine kinase family TSC22 PF01166.18 PVD20650.1 - 0.21 11.9 2.3 0.57 10.5 2.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Calpain_III PF01067.22 PVD20650.1 - 0.31 11.3 7.6 0.4 10.9 1.1 2.7 1 1 1 2 2 2 0 Calpain large subunit, domain III Pkinase PF00069.25 PVD20651.1 - 2.4e-72 243.5 0.0 3.3e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20651.1 - 4.3e-33 114.7 0.0 5.8e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD20651.1 - 4.7e-07 29.4 0.0 2.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 PVD20651.1 - 0.011 15.3 0.6 4.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PVD20651.1 - 0.033 13.6 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 PVD20652.1 - 2.1e-15 56.9 13.2 9.6e-05 23.1 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD20652.1 - 2.2e-05 24.7 0.1 0.62 10.4 0.0 3.7 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Tox-HDC PF15656.6 PVD20652.1 - 0.16 12.1 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Peptidase_M22 PF00814.25 PVD20653.1 - 1.4e-51 175.8 0.1 1.1e-49 169.5 0.1 2.0 1 1 0 1 1 1 1 Glycoprotease family Methyltransf_31 PF13847.6 PVD20654.1 - 7.8e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD20654.1 - 0.00013 22.6 0.0 0.00023 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD20654.1 - 0.019 15.7 0.0 0.036 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PVD20654.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PigN PF04987.14 PVD20655.1 - 5.4e-66 223.3 30.4 7.6e-66 222.8 30.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) TPX2_importin PF12214.8 PVD20655.1 - 1.6e-20 74.0 46.7 8.6e-10 39.1 0.4 6.7 2 2 2 5 5 5 4 Cell cycle regulated microtubule associated protein Phosphodiest PF01663.22 PVD20655.1 - 9.7e-10 38.6 0.0 8.5e-08 32.2 0.0 2.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CHASE6_C PF17150.4 PVD20655.1 - 0.28 11.9 1.0 0.6 10.8 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain MT-A70 PF05063.14 PVD20656.1 - 2.3e-60 203.4 0.0 5.3e-60 202.3 0.0 1.6 1 0 0 1 1 1 1 MT-A70 Tyrosinase PF00264.20 PVD20657.1 - 5.8e-30 105.2 0.3 1.2e-14 55.2 0.2 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase Alpha_kinase PF02816.18 PVD20658.1 - 2.1e-07 31.3 0.0 2.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Methyltr_RsmB-F PF01189.17 PVD20659.1 - 5e-40 137.3 0.0 3e-39 134.7 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SF3a60_bindingd PF12108.8 PVD20659.1 - 0.033 14.1 0.3 0.07 13.0 0.3 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain FtsJ PF01728.19 PVD20659.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Neur_chan_memb PF02932.16 PVD20660.1 - 1.3e-30 107.3 4.9 5.2e-26 92.2 0.4 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region BESS PF02944.20 PVD20660.1 - 0.48 10.3 2.3 13 5.7 0.6 2.3 1 1 1 2 2 2 0 BESS motif Neur_chan_LBD PF02931.23 PVD20661.1 - 9.7e-40 136.3 0.2 2.8e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Ank_4 PF13637.6 PVD20662.1 - 1e-16 61.1 0.6 6e-11 42.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20662.1 - 1.6e-16 60.6 0.2 3.9e-16 59.4 0.2 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD20662.1 - 3.5e-14 52.5 1.3 2.4e-07 30.9 0.2 3.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD20662.1 - 2e-13 49.2 0.2 3e-06 27.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PVD20662.1 - 1.6e-11 44.2 0.6 3.4e-06 27.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIR PF01582.20 PVD20663.1 - 1.1e-16 61.2 0.6 2.7e-16 59.9 0.6 1.7 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD20663.1 - 2.1e-16 60.6 0.1 4.8e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 PVD20663.1 - 1.1e-06 28.9 0.1 5e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 PVD20663.1 - 2e-05 24.8 0.9 0.038 14.4 0.9 4.0 2 2 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20663.1 - 0.00014 21.6 0.1 0.25 11.1 0.0 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRRCT PF01463.24 PVD20663.1 - 0.0054 17.2 0.2 0.022 15.3 0.2 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 PVD20663.1 - 0.036 14.1 0.9 15 5.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 PVD20663.1 - 0.2 12.3 1.5 69 4.6 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat TIR PF01582.20 PVD20664.1 - 1e-19 71.0 0.3 2e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD20664.1 - 1e-18 68.0 0.2 4.3e-18 66.0 0.1 2.1 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 PVD20664.1 - 2.8e-06 27.7 0.7 1.2e-05 25.6 0.3 2.3 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 PVD20664.1 - 0.00014 22.2 1.9 0.4 11.2 0.9 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20664.1 - 0.00015 21.4 0.5 0.0047 16.7 0.4 3.0 2 1 1 3 3 3 2 Leucine rich repeat BID PF06393.11 PVD20664.1 - 0.42 10.1 3.3 17 4.9 0.1 3.4 3 1 1 4 4 4 0 BH3 interacting domain (BID) LRR_1 PF00560.33 PVD20664.1 - 2.3 9.1 4.7 2.4e+02 3.0 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat TIR PF01582.20 PVD20665.1 - 4.3e-18 65.7 0.2 7.1e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD20665.1 - 1e-16 61.6 0.1 2.4e-16 60.4 0.1 1.7 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 PVD20665.1 - 3.2e-06 27.5 0.2 3.2e-06 27.5 0.2 2.5 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 PVD20665.1 - 0.013 15.9 3.1 0.54 10.8 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20665.1 - 0.057 13.2 1.9 0.57 10.0 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat LRRCT PF01463.24 PVD20665.1 - 0.12 13.0 0.1 0.39 11.4 0.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain UIM PF02809.20 PVD20665.1 - 1.4 9.0 3.9 3 8.0 3.9 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.20 PVD20666.1 - 2.7e-17 63.1 0.2 6.3e-17 61.9 0.2 1.6 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD20666.1 - 6.9e-15 55.7 0.1 1.4e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 PVD20666.1 - 0.00011 22.5 0.0 0.00038 20.8 0.0 1.9 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 PVD20666.1 - 0.0025 18.2 4.7 0.7 10.4 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRCT PF01463.24 PVD20666.1 - 0.011 16.2 0.2 0.043 14.4 0.2 2.2 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_8 PF13855.6 PVD20666.1 - 0.034 13.9 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 Leucine rich repeat COQ9 PF08511.11 PVD20667.1 - 8.4e-34 115.2 1.3 1.7e-33 114.2 1.3 1.5 1 0 0 1 1 1 1 COQ9 Kinetochor_Ybp2 PF08568.10 PVD20667.1 - 1.2e-24 86.8 0.0 4.9e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Fanconi_A_N PF15865.5 PVD20667.1 - 0.016 14.6 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus FHA PF00498.26 PVD20668.1 - 2.2e-05 24.7 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD20668.1 - 0.0037 17.6 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RBFA PF02033.18 PVD20669.1 - 6.7e-14 52.2 0.0 1.4e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A Rox3 PF08633.10 PVD20669.1 - 0.027 14.7 0.2 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 Rox3 mediator complex subunit TFIIA_gamma_N PF02268.16 PVD20669.1 - 0.028 14.4 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Cnl2_NKP2 PF09447.10 PVD20669.1 - 0.07 13.3 1.8 0.45 10.7 0.1 2.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein CENP-T_C PF15511.6 PVD20670.1 - 2e-28 98.7 0.8 1.2e-27 96.1 0.1 2.3 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PVD20670.1 - 3.3e-08 33.8 0.1 1e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 PVD20670.1 - 0.0007 20.0 0.1 0.0007 20.0 0.1 4.2 4 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 PVD20670.1 - 0.038 14.0 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PVD20670.1 - 0.046 14.0 0.4 0.12 12.7 0.4 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_Tnp_IS66 PF03050.14 PVD20670.1 - 0.048 13.1 0.3 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Transposase IS66 family Proteasome PF00227.26 PVD20671.1 - 5.9e-59 198.8 0.2 7.9e-59 198.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1192 PF06698.11 PVD20671.1 - 0.13 12.3 2.2 0.67 10.1 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) EGF_CA PF07645.15 PVD20672.1 - 6e-68 224.8 150.4 6.1e-09 36.0 8.8 12.2 9 3 2 11 11 11 10 Calcium-binding EGF domain cEGF PF12662.7 PVD20672.1 - 1.8e-64 213.2 101.0 1.7e-09 37.4 2.6 11.9 11 0 0 11 11 11 11 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD20672.1 - 4.9e-58 193.1 163.5 4.2e-12 46.1 9.8 11.6 9 2 2 11 11 11 11 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PVD20672.1 - 3.4e-21 75.1 145.1 0.0002 21.5 4.1 13.1 12 1 1 13 13 13 10 EGF domain EGF PF00008.27 PVD20672.1 - 3e-18 65.8 162.6 0.0037 17.5 6.8 13.1 12 1 1 13 13 13 11 EGF-like domain Plasmod_Pvs28 PF06247.11 PVD20672.1 - 4.9e-12 45.9 110.9 0.0036 17.6 8.9 11.7 10 1 1 11 11 11 8 Pvs28 EGF domain hEGF PF12661.7 PVD20672.1 - 4e-11 43.1 168.3 0.002 18.7 6.8 16.0 16 1 0 16 16 16 9 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 PVD20672.1 - 4.5 7.4 108.4 0.13 12.4 5.9 11.4 9 2 2 11 11 11 0 MSP1 EGF domain 1 EGF_2 PF07974.13 PVD20673.1 - 0.0019 18.5 6.9 0.0033 17.8 6.9 1.3 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 PVD20673.1 - 0.74 10.2 9.1 1.4 9.3 9.1 1.5 1 0 0 1 1 1 0 EGF-like domain TMEM51 PF15345.6 PVD20676.1 - 0.0028 17.5 0.0 0.0088 15.9 0.0 1.9 1 1 0 1 1 1 1 Transmembrane protein 51 Phage_Gp23 PF10669.9 PVD20676.1 - 0.019 15.3 0.0 0.077 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) EphA2_TM PF14575.6 PVD20676.1 - 0.077 13.9 0.0 0.38 11.7 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 PVD20676.1 - 6.4 6.4 5.8 1.6 8.4 0.1 2.6 3 0 0 3 3 3 0 FAM176 family BtpA PF03437.15 PVD20677.1 - 1.7e-48 165.3 1.2 2.1e-48 165.0 1.2 1.0 1 0 0 1 1 1 1 BtpA family His_biosynth PF00977.21 PVD20677.1 - 0.03 13.8 0.1 0.26 10.7 0.1 2.1 1 1 0 2 2 2 0 Histidine biosynthesis protein Cyclin_N PF00134.23 PVD20678.1 - 8.7e-38 128.9 2.0 1.8e-37 128.0 2.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PVD20678.1 - 5.4e-14 52.3 0.9 2.3e-13 50.3 0.2 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain CIMR PF00878.18 PVD20678.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Phospholip_A2_2 PF05826.12 PVD20679.1 - 5.8e-30 103.4 2.9 5.8e-30 103.4 2.9 2.4 3 0 0 3 3 3 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 PVD20679.1 - 1 9.8 13.2 11 6.5 8.8 2.8 2 1 0 2 2 2 0 Phospholipase A2 Apolipoprotein PF01442.18 PVD20680.1 - 0.015 15.2 0.0 0.06 13.2 0.0 1.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TMP_2 PF06791.13 PVD20680.1 - 0.094 12.4 14.2 0.76 9.4 5.0 3.0 2 1 1 3 3 3 0 Prophage tail length tape measure protein Senescence PF06911.12 PVD20680.1 - 0.16 12.3 16.2 0.33 11.3 8.2 2.9 1 1 1 2 2 2 0 Senescence-associated protein Collagen_mid PF15984.5 PVD20681.1 - 0.18 11.6 66.2 0.88 9.3 50.2 2.9 1 1 1 2 2 2 0 Bacterial collagen, middle region DUF5610 PF18433.1 PVD20681.1 - 7.6 7.1 10.6 38 4.8 0.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF5610) Apolipoprotein PF01442.18 PVD20682.1 - 4e-06 26.8 0.3 0.00099 19.0 0.0 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Senescence PF06911.12 PVD20682.1 - 0.011 16.0 26.3 0.59 10.4 8.5 3.6 2 1 1 3 3 3 0 Senescence-associated protein Baculo_PEP_C PF04513.12 PVD20682.1 - 0.032 14.3 0.0 0.46 10.5 0.0 2.6 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tape_meas_lam_C PF09718.10 PVD20682.1 - 0.048 13.8 13.3 1.2 9.3 1.4 5.2 2 2 3 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF948 PF06103.11 PVD20682.1 - 0.072 13.3 2.7 1.2 9.5 0.2 3.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DAGK_prokar PF01219.19 PVD20682.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.4 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase Collagen_mid PF15984.5 PVD20682.1 - 0.35 10.6 34.5 0.029 14.1 15.6 2.8 1 1 1 2 2 2 0 Bacterial collagen, middle region ATG_C PF09333.11 PVD20682.1 - 0.59 10.5 7.9 15 6.0 0.7 3.7 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain Phasin_2 PF09361.10 PVD20682.1 - 0.81 10.0 10.0 1.5 9.1 0.6 3.8 1 1 2 3 3 3 0 Phasin protein WXG100 PF06013.12 PVD20682.1 - 5.1 7.4 9.0 0.69 10.2 0.7 3.4 3 2 0 3 3 3 0 Proteins of 100 residues with WXG Chlorosome_CsmC PF11098.8 PVD20682.1 - 8.3 6.4 37.4 0.067 13.2 13.1 3.1 1 1 2 3 3 3 0 Chlorosome envelope protein C Phospholip_A2_2 PF05826.12 PVD20683.1 - 2.6e-28 98.1 0.9 2.6e-28 98.1 0.9 2.0 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 PVD20683.1 - 0.31 11.5 9.1 12 6.4 9.1 2.6 1 1 0 1 1 1 0 Phospholipase A2 DSPc PF00782.20 PVD20684.1 - 2.7e-22 79.0 0.0 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD20684.1 - 0.048 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Cadherin PF00028.17 PVD20687.1 - 1.8e-94 310.3 2.2 1.2e-15 57.7 0.0 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD20687.1 - 6.8e-10 38.6 0.0 9e-07 28.6 0.0 5.1 5 1 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 PVD20687.1 - 3.5e-08 33.4 9.1 0.13 12.3 0.3 5.5 5 0 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 PVD20687.1 - 0.00012 22.6 40.2 0.012 16.2 0.2 6.7 7 0 0 7 7 7 4 Bacterial cadherin-like domain Protocadherin PF08374.11 PVD20687.1 - 0.025 14.6 0.2 0.064 13.2 0.2 1.6 1 0 0 1 1 1 0 Protocadherin Herpes_gE PF02480.16 PVD20687.1 - 0.034 12.9 0.7 3.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 PVD20687.1 - 0.075 13.9 0.0 0.54 11.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cys_Met_Meta_PP PF01053.20 PVD20690.1 - 2.2e-113 378.7 0.0 2.4e-112 375.3 0.0 1.9 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PVD20690.1 - 2.2e-07 30.4 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 PVD20691.1 - 1.8e-92 310.3 0.0 2.1e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ank_4 PF13637.6 PVD20692.1 - 1.7e-29 101.8 0.8 5.9e-10 39.5 0.1 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD20692.1 - 4.9e-28 96.8 9.4 1.5e-07 31.5 0.3 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD20692.1 - 2.8e-27 95.1 4.1 1e-13 51.7 1.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD20692.1 - 9.1e-19 65.6 5.7 0.00066 19.9 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 PVD20692.1 - 3e-18 65.4 12.5 0.00025 21.4 0.3 6.2 7 0 0 7 7 7 4 Ankyrin repeat Methyltransf_32 PF13679.6 PVD20692.1 - 0.027 14.4 9.5 0.043 13.8 2.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain F-box-like PF12937.7 PVD20693.1 - 1.6e-09 37.5 5.9 1.6e-09 37.5 5.9 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD20693.1 - 1.9e-06 27.6 2.1 1.9e-06 27.6 2.1 3.0 3 0 0 3 3 3 1 F-box domain RsdA_SigD_bd PF16751.5 PVD20693.1 - 0.058 13.7 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region DUF1678 PF07913.11 PVD20693.1 - 0.098 12.4 0.2 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) RRM_1 PF00076.22 PVD20694.1 - 4.1e-18 65.0 0.0 1.6e-06 27.9 0.0 5.6 5 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 PVD20694.1 - 0.07 13.7 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Exonuclease PHY PF00360.20 PVD20694.1 - 0.11 11.8 0.0 3 7.1 0.0 2.2 2 0 0 2 2 2 0 Phytochrome region tRNA-synt_1c PF00749.21 PVD20694.1 - 0.14 11.0 0.1 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain CPBP PF02517.16 PVD20695.1 - 2.4e-07 31.0 2.0 3.7e-07 30.4 0.5 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF3483 PF11982.8 PVD20695.1 - 0.018 14.7 0.3 0.018 14.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) Aminotran_1_2 PF00155.21 PVD20696.1 - 2.3e-37 129.0 0.0 2.7e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Limkain-b1 PF11608.8 PVD20696.1 - 0.002 18.2 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 Beta_elim_lyase PF01212.21 PVD20696.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Forkhead PF00250.18 PVD20697.1 - 6.7e-19 67.9 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Ras PF00071.22 PVD20698.1 - 3.1e-24 85.4 0.1 3.6e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20698.1 - 3.6e-11 43.3 0.3 5.5e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD20698.1 - 3.6e-07 29.8 0.2 4.5e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD20698.1 - 9.9e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD20698.1 - 0.0038 16.8 0.1 0.055 13.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD20698.1 - 0.015 15.2 0.2 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 PVD20698.1 - 0.025 14.7 0.1 1.8 8.6 0.0 2.2 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.20 PVD20698.1 - 0.025 13.7 0.1 0.041 13.0 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 PVD20698.1 - 0.037 14.3 0.1 0.43 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 PVD20698.1 - 0.15 11.8 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 PVD20699.1 - 1.6e-42 145.1 0.0 2.9e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PVD20699.1 - 4.2e-29 100.3 0.1 1.9e-28 98.2 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 PVD20699.1 - 2.9e-24 84.9 7.2 6.7e-24 83.7 7.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 PVD20699.1 - 3e-08 33.3 0.0 1.6e-07 31.0 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 PVD20699.1 - 6.8e-06 26.6 0.2 0.0013 19.2 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 PVD20699.1 - 2.1e-05 23.9 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 PVD20699.1 - 2.3e-05 24.7 0.6 0.0049 17.1 0.2 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PVD20699.1 - 2.7e-05 24.0 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PVD20699.1 - 2.9e-05 23.9 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 PVD20699.1 - 5.4e-05 23.2 0.0 0.00017 21.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 PVD20699.1 - 6.3e-05 23.0 0.0 0.00016 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PVD20699.1 - 0.00029 20.1 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 PVD20699.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 PVD20699.1 - 0.00045 20.8 0.0 0.0012 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PVD20699.1 - 0.00074 19.3 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PVD20699.1 - 0.0033 17.6 0.0 0.0087 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 PVD20699.1 - 0.0039 17.5 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 PVD20699.1 - 0.0063 16.1 0.2 0.64 9.6 0.1 2.7 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 PVD20699.1 - 0.0071 16.3 0.0 0.16 11.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain ATPase PF06745.13 PVD20699.1 - 0.026 13.9 0.2 7.4 5.8 0.0 2.4 1 1 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 PVD20699.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 PVD20699.1 - 0.036 13.5 0.0 7.2 6.0 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 PVD20699.1 - 0.038 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 PVD20699.1 - 0.038 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 PVD20699.1 - 0.052 13.2 0.0 0.19 11.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 PVD20699.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 PVD20699.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 PVD20699.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD20699.1 - 0.11 13.0 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.6 PVD20699.1 - 0.21 11.3 1.6 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD20699.1 - 0.41 10.5 4.8 1.2 9.0 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea USP8_dimer PF08969.11 PVD20699.1 - 3.1 8.0 7.3 6 7.1 7.3 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain DHC_N1 PF08385.12 PVD20700.1 - 1.9e-149 498.9 10.6 1.9e-149 498.9 10.6 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PVD20700.1 - 1.3e-141 471.3 0.0 6.2e-141 469.1 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD20700.1 - 3.6e-123 411.6 16.7 3.6e-123 411.6 16.7 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD20700.1 - 1.3e-90 303.3 0.0 3.3e-90 301.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD20700.1 - 1.8e-83 279.0 4.7 3.7e-83 278.0 2.2 3.2 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD20700.1 - 1.5e-69 233.1 2.9 1.9e-64 216.5 0.1 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD20700.1 - 1.4e-55 187.6 0.1 3.8e-55 186.2 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 PVD20700.1 - 2e-51 175.0 0.0 2e-51 175.0 0.0 3.3 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain MT PF12777.7 PVD20700.1 - 1.2e-41 142.9 7.7 1.2e-41 142.9 7.7 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD20700.1 - 4.2e-38 130.1 0.0 2.6e-37 127.5 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD20700.1 - 3.6e-24 85.3 0.4 2.6e-23 82.5 0.1 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD20700.1 - 4.2e-20 72.1 0.0 3.6e-06 27.0 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD20700.1 - 8.7e-17 61.2 0.1 4.6e-16 58.9 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PVD20700.1 - 1.4e-06 28.6 1.3 2.1 8.6 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 PVD20700.1 - 2.7e-05 24.6 0.1 1.1 9.6 0.0 4.9 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 PVD20700.1 - 3.3e-05 24.3 0.4 7.7 7.0 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 PVD20700.1 - 0.0087 16.3 0.1 16 5.7 0.0 3.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 PVD20700.1 - 0.02 14.6 0.0 2.6 7.7 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PVD20700.1 - 0.058 12.8 0.0 7 6.0 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 PVD20700.1 - 0.12 12.5 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 PVD20700.1 - 0.14 12.6 0.2 5.9 7.3 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 PVD20700.1 - 0.7 10.4 2.3 5.2 7.6 0.0 3.7 4 0 0 4 4 3 0 ABC transporter HrpB7 PF09486.10 PVD20700.1 - 5.3 7.4 16.7 3.1 8.2 0.2 3.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) AAA_6 PF12774.7 PVD20701.1 - 8.9e-143 475.2 0.2 9.2e-142 471.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PVD20701.1 - 1.8e-130 436.3 27.5 1.6e-81 274.7 10.6 3.9 3 2 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PVD20701.1 - 1.3e-94 317.6 9.9 1.8e-90 303.9 5.1 4.5 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD20701.1 - 9.3e-93 310.8 0.7 1e-91 307.4 0.0 3.2 2 1 1 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD20701.1 - 1.3e-90 303.2 0.0 4.1e-90 301.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD20701.1 - 5e-84 280.8 4.1 2.6e-83 278.5 2.9 3.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD20701.1 - 3.9e-67 225.3 4.0 4.6e-62 208.8 0.1 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD20701.1 - 3e-52 176.8 0.0 7.6e-52 175.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD20701.1 - 4e-39 134.6 7.6 7.4e-39 133.7 7.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD20701.1 - 8.5e-39 132.3 0.6 8e-38 129.2 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PVD20701.1 - 4.6e-21 75.3 0.0 1.6e-06 28.1 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD20701.1 - 8.1e-20 70.9 0.3 6.8e-19 67.9 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 PVD20701.1 - 2.9e-18 66.2 0.9 1.1e-17 64.4 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 PVD20701.1 - 1.1e-06 28.9 0.9 0.32 11.3 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 PVD20701.1 - 8.9e-05 22.9 0.4 0.68 10.3 0.0 4.5 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 PVD20701.1 - 0.00027 21.4 0.1 11 6.5 0.0 4.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 PVD20701.1 - 0.069 13.4 0.1 17 5.6 0.0 3.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 PVD20701.1 - 0.073 12.8 0.1 5 6.8 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 PVD20701.1 - 0.075 13.4 0.5 9.9 6.6 0.0 4.1 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 PVD20701.1 - 0.2 11.8 1.6 3.5 7.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain DHC_N1 PF08385.12 PVD20702.1 - 4.7e-179 596.7 14.4 4.7e-179 596.7 14.4 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PVD20702.1 - 1.9e-144 480.6 0.0 8.3e-144 478.5 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD20702.1 - 6.3e-128 427.3 8.2 6.3e-128 427.3 8.2 4.1 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD20702.1 - 2.1e-99 332.6 0.0 2.1e-99 332.6 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD20702.1 - 3.4e-94 315.0 0.0 1e-93 313.4 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD20702.1 - 5.6e-86 287.2 5.9 1.5e-84 282.6 3.0 3.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD20702.1 - 5.7e-69 231.3 0.3 6e-64 214.9 0.0 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD20702.1 - 4.8e-55 185.8 0.1 1.2e-54 184.6 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD20702.1 - 2.7e-41 141.8 9.6 2.7e-41 141.8 9.6 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD20702.1 - 4.5e-40 136.5 0.0 3.7e-39 133.5 0.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PVD20702.1 - 4.8e-22 78.4 0.0 2.4e-06 27.6 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PVD20702.1 - 2.2e-20 73.1 2.4 7.3e-19 68.1 0.2 4.2 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD20702.1 - 4.2e-16 59.0 0.2 3.3e-15 56.1 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 PVD20702.1 - 2.9e-05 24.3 0.2 1.4 9.2 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 PVD20702.1 - 8.5e-05 23.0 0.1 8.7 6.8 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD20702.1 - 0.0035 17.8 0.7 8.2 6.8 0.0 5.1 5 0 0 5 5 4 1 AAA ATPase domain Roc PF08477.13 PVD20702.1 - 0.048 13.9 0.0 29 4.9 0.0 4.0 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase GlnD_UR_UTase PF08335.11 PVD20702.1 - 0.24 11.5 1.5 0.82 9.8 0.0 2.7 3 0 0 3 3 3 0 GlnD PII-uridylyltransferase ABC_tran PF00005.27 PVD20702.1 - 0.26 11.8 1.0 30 5.1 0.0 4.2 4 0 0 4 4 4 0 ABC transporter PNK3P PF08645.11 PVD20703.1 - 4.1e-47 159.9 0.0 8.1e-47 158.9 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase FHA_2 PF17913.1 PVD20703.1 - 3.7e-30 104.0 0.0 8.3e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain AAA_33 PF13671.6 PVD20703.1 - 2.1e-16 60.4 0.0 8.5e-14 51.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain FHA PF00498.26 PVD20703.1 - 0.007 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain Hydrolase_6 PF13344.6 PVD20703.1 - 0.11 12.6 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gaa1 PF04114.14 PVD20704.1 - 3.2e-148 494.9 0.9 3.9e-148 494.6 0.9 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PGI PF00342.19 PVD20705.1 - 5.2e-62 210.0 0.6 1.5e-51 175.5 0.1 2.0 2 0 0 2 2 2 2 Phosphoglucose isomerase DUF4745 PF15923.5 PVD20706.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) Spore_III_AB PF09548.10 PVD20706.1 - 0.18 11.9 0.7 5.4 7.1 0.4 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GSK-3_bind PF05350.12 PVD20707.1 - 0.0084 15.4 0.5 0.17 11.2 0.3 2.2 1 1 1 2 2 2 2 Glycogen synthase kinase-3 binding Fucokinase PF07959.12 PVD20708.1 - 1.5e-79 267.9 0.4 2e-79 267.5 0.4 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 PVD20708.1 - 8.4e-07 29.1 3.1 9e-07 29.0 0.8 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PVD20708.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Capsid-VNN PF11729.8 PVD20708.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein BIR PF00653.21 PVD20709.1 - 2e-31 108.5 13.5 2.1e-14 53.9 0.6 4.2 4 0 0 4 4 3 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD20709.1 - 7.2e-13 48.2 8.4 7.2e-13 48.2 8.4 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD20709.1 - 1.2e-05 25.1 7.8 1.2e-05 25.1 7.8 3.2 5 0 0 5 5 4 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD20709.1 - 4.2e-05 23.8 10.3 4.2e-05 23.8 10.3 3.7 4 1 0 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD20709.1 - 0.011 15.6 10.3 0.011 15.6 10.3 3.0 4 0 0 4 4 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD20709.1 - 0.069 13.1 15.6 0.027 14.4 8.8 3.3 3 0 0 3 3 3 0 zinc-RING finger domain DUF3552 PF12072.8 PVD20709.1 - 0.07 12.5 33.7 0.022 14.2 25.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) zf-RING_4 PF14570.6 PVD20709.1 - 0.1 12.4 8.6 1.2 8.9 0.0 3.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PVD20709.1 - 0.11 12.2 3.3 0.27 10.9 3.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger SNAD4 PF18750.1 PVD20709.1 - 0.14 12.3 2.4 0.52 10.5 2.4 2.0 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Prok-RING_1 PF14446.6 PVD20709.1 - 0.23 11.4 0.0 0.23 11.4 0.0 4.5 5 0 0 5 5 4 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 PVD20709.1 - 0.46 10.5 3.2 0.84 9.7 0.1 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF4200 PF13863.6 PVD20709.1 - 2.3 8.6 30.2 25 5.3 30.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.14 PVD20709.1 - 8.7 6.7 38.7 0.97 9.8 23.9 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) adh_short_C2 PF13561.6 PVD20710.1 - 1.2e-59 201.8 0.4 1.5e-59 201.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD20710.1 - 2.8e-48 164.0 0.4 3.4e-48 163.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD20710.1 - 1.1e-08 35.2 1.7 5.3e-08 33.0 1.7 1.9 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 PVD20710.1 - 0.068 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 PVD20710.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Orn_Arg_deC_N PF02784.16 PVD20710.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 7tm_1 PF00001.21 PVD20711.1 - 9.8e-19 67.7 0.1 1.3e-18 67.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM171 PF15471.6 PVD20711.1 - 0.0001 21.4 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein family 171 7TM_GPCR_Srw PF10324.9 PVD20711.1 - 0.0075 15.6 5.2 0.65 9.2 0.3 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw VMA21 PF09446.10 PVD20711.1 - 0.021 14.9 1.5 0.071 13.2 1.5 1.9 1 0 0 1 1 1 0 VMA21-like domain PAN_4 PF14295.6 PVD20712.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 PAN domain Pyr_redox_3 PF13738.6 PVD20713.1 - 2.6e-11 43.3 0.0 2.6e-07 30.2 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD20713.1 - 1.9e-05 24.0 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 PVD20713.1 - 3.8e-05 23.1 0.0 0.0026 17.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RNB PF00773.19 PVD20715.1 - 1.4e-99 333.6 0.2 2.2e-99 332.9 0.2 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.6 PVD20715.1 - 6.3e-15 55.6 0.5 1.8e-14 54.1 0.5 1.8 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 PVD20715.1 - 2.1e-13 50.2 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 PVD20715.1 - 6.7e-13 48.5 0.0 1.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 PVD20715.1 - 5.5e-06 26.2 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 PVD20715.1 - 0.093 13.1 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal Rad33 PF08730.10 PVD20715.1 - 0.11 12.5 0.6 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Rad33 Ank_2 PF12796.7 PVD20716.1 - 2.7e-11 43.9 0.1 1.1e-05 25.9 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD20716.1 - 4.3e-11 42.0 0.9 0.043 14.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PVD20716.1 - 5.8e-11 42.3 0.7 0.071 13.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 PVD20716.1 - 2.3e-08 34.4 0.4 0.0037 17.8 0.0 4.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD20716.1 - 5e-08 33.2 1.2 1.3e-07 31.9 1.2 1.7 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 PVD20716.1 - 0.00071 19.8 0.2 0.11 12.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF896 PF05979.12 PVD20716.1 - 0.12 12.3 0.1 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Y_phosphatase PF00102.27 PVD20717.1 - 6.1e-73 245.3 0.0 8.5e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD20717.1 - 0.0015 18.3 0.2 0.0038 17.0 0.2 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD20717.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Na_Pi_cotrans PF02690.15 PVD20718.1 - 1.4e-33 115.9 21.8 6.5e-20 71.7 7.4 2.7 2 0 0 2 2 2 2 Na+/Pi-cotransporter PRT_C PF08372.10 PVD20718.1 - 0.12 12.1 0.8 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Cadherin PF00028.17 PVD20719.1 - 9.5e-114 372.1 47.4 8.1e-18 64.7 0.2 16.3 16 1 1 17 17 17 14 Cadherin domain Cadherin_C PF01049.17 PVD20719.1 - 3.8e-45 153.8 2.0 9.8e-45 152.4 2.0 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 PVD20719.1 - 7.7e-38 129.9 1.2 7.6e-24 84.7 0.0 2.9 1 1 1 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD20719.1 - 3.1e-24 85.6 1.4 2.1e-15 57.1 0.0 3.3 2 1 1 3 3 3 2 Laminin G domain Cadherin_3 PF16184.5 PVD20719.1 - 1.9e-07 31.0 19.6 0.48 10.4 0.1 7.9 7 0 0 7 7 7 4 Cadherin-like Cadherin_2 PF08266.12 PVD20719.1 - 3.1e-07 30.1 0.0 0.41 10.5 0.0 5.6 5 0 0 5 5 5 2 Cadherin-like EGF PF00008.27 PVD20719.1 - 0.085 13.2 43.4 0.013 15.8 8.6 3.7 3 0 0 3 3 3 0 EGF-like domain Cadherin_pro PF08758.11 PVD20719.1 - 0.18 12.0 1.3 1.8 8.8 0.2 3.4 3 0 0 3 3 3 0 Cadherin prodomain like Syndecan PF01034.20 PVD20719.1 - 0.2 11.6 0.3 0.49 10.3 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 PVD20719.1 - 0.32 10.8 1.1 0.93 9.3 1.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Invasin_D3 PF09134.10 PVD20719.1 - 6.4 7.2 32.0 3.2 8.1 0.0 9.7 10 0 0 10 10 9 0 Invasin, domain 3 Cadherin PF00028.17 PVD20720.1 - 3.4e-133 434.5 50.1 1.8e-16 60.3 0.1 16.7 17 0 0 17 17 17 15 Cadherin domain Laminin_G_2 PF02210.24 PVD20720.1 - 2e-44 151.2 2.0 2e-23 83.4 0.0 3.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD20720.1 - 4e-31 108.0 0.4 3.1e-16 59.8 0.0 3.3 2 0 0 2 2 2 2 Laminin G domain Cadherin_3 PF16184.5 PVD20720.1 - 1.2e-07 31.7 22.8 1.5 8.8 0.1 9.7 9 0 0 9 9 9 3 Cadherin-like Cadherin_2 PF08266.12 PVD20720.1 - 7.5e-07 28.9 0.0 0.42 10.5 0.0 5.5 6 0 0 6 6 6 2 Cadherin-like Cadherin_pro PF08758.11 PVD20720.1 - 2.5e-05 24.3 4.9 1.9 8.7 0.2 7.0 7 0 0 7 7 7 1 Cadherin prodomain like EGF_MSP1_1 PF12946.7 PVD20720.1 - 0.00035 20.6 3.7 0.00035 20.6 3.7 4.5 6 0 0 6 6 6 1 MSP1 EGF domain 1 RET_CLD1 PF17756.1 PVD20720.1 - 0.00083 19.6 0.1 4.3 7.6 0.0 5.1 5 0 0 5 5 5 1 RET Cadherin like domain 1 Laminin_G_3 PF13385.6 PVD20720.1 - 0.072 13.2 0.8 5.6 7.1 0.8 3.6 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Cadherin PF00028.17 PVD20721.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Cadherin domain EF-hand_1 PF00036.32 PVD20722.1 - 2.7e-23 79.7 0.7 1.1e-07 30.9 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PVD20722.1 - 1.3e-19 70.4 0.7 8.7e-17 61.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD20722.1 - 7.4e-19 66.0 0.3 4.8e-07 29.2 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PVD20722.1 - 1.3e-18 66.6 4.7 4.7e-11 42.4 0.0 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD20722.1 - 1.7e-17 62.0 3.6 6.4e-07 28.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 PVD20722.1 - 0.0014 18.9 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain PMBR PF09373.10 PVD20722.1 - 0.0014 18.7 0.0 1.1 9.6 0.0 3.3 3 0 0 3 3 3 1 Pseudomurein-binding repeat Dockerin_1 PF00404.18 PVD20722.1 - 0.002 18.3 0.0 0.0045 17.2 0.0 1.6 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_4 PF12763.7 PVD20722.1 - 0.0022 17.9 1.0 0.16 12.0 0.0 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PVD20722.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.6 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 PVD20722.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 Caleosin related protein VCBS PF13517.6 PVD20722.1 - 0.036 14.6 0.1 0.079 13.6 0.1 1.7 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Carb_anhydrase PF00194.21 PVD20723.1 - 4.9e-86 288.4 0.0 5.7e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Jas PF16135.5 PVD20724.1 - 0.044 14.0 0.4 0.078 13.2 0.4 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling F-box-like PF12937.7 PVD20726.1 - 4.9e-12 45.6 1.9 6.8e-12 45.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD20726.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD20726.1 - 0.0068 16.3 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 F-box RabGAP-TBC PF00566.18 PVD20727.1 - 2.3e-28 99.3 0.2 3.6e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MBOAT PF03062.19 PVD20728.1 - 1.1e-38 133.5 21.5 1.5e-38 133.1 21.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PVD20728.1 - 0.0011 19.2 3.9 0.0027 17.9 3.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ThiF PF00899.21 PVD20729.1 - 6.2e-72 241.9 0.0 2.7e-71 239.8 0.0 1.8 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 PVD20729.1 - 2.7e-22 79.2 0.3 2.7e-22 79.2 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PVD20729.1 - 7.7e-10 39.1 0.3 0.00055 19.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site UBA2_C PF16195.5 PVD20729.1 - 1.2e-06 29.1 2.9 2.5e-06 28.1 2.9 1.4 1 0 0 1 1 1 1 SUMO-activating enzyme subunit 2 C-terminus NAD_binding_7 PF13241.6 PVD20729.1 - 6.1e-05 23.4 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 PVD20729.1 - 0.0063 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 PVD20729.1 - 0.19 12.3 0.5 0.59 10.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HAUS4 PF14735.6 PVD20730.1 - 5.7e-17 62.2 1.9 6.9e-17 61.9 0.1 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 RTP1_C1 PF10363.9 PVD20732.1 - 4.5e-32 110.5 0.3 6.7e-30 103.6 0.0 3.4 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 PVD20732.1 - 1.3e-06 28.7 0.1 0.028 14.8 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 PVD20732.1 - 2.3e-05 24.3 0.5 5.3 7.6 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 PVD20732.1 - 0.00032 20.8 5.1 0.034 14.2 0.7 4.8 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 RTP1_C2 PF10304.9 PVD20732.1 - 0.00098 18.8 0.9 0.00098 18.8 0.9 3.1 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 2 Vac14_Fab1_bd PF12755.7 PVD20732.1 - 0.028 15.0 0.0 0.71 10.5 0.0 2.9 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3730 PF12530.8 PVD20732.1 - 0.03 13.9 2.3 0.05 13.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3730) CLASP_N PF12348.8 PVD20732.1 - 0.11 12.0 1.5 16 5.0 0.1 3.7 3 1 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 PVD20732.1 - 0.12 12.9 4.9 11 6.7 0.1 4.7 4 1 1 5 5 5 0 HEAT-like repeat ShK PF01549.24 PVD20733.1 - 5e-19 68.6 76.5 1.2e-05 25.8 9.9 5.4 5 1 0 5 5 5 4 ShK domain-like ShK PF01549.24 PVD20734.1 - 5.4e-24 84.4 67.7 7.6e-07 29.6 10.3 4.3 4 0 0 4 4 4 4 ShK domain-like Baculo_PEP_C PF04513.12 PVD20734.1 - 8.5e-11 42.1 2.3 0.00027 21.0 0.0 3.9 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 PVD20734.1 - 5.5e-09 36.3 7.8 0.0017 18.5 0.2 3.6 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 PVD20734.1 - 1.7e-07 31.3 0.1 0.00087 19.2 0.0 2.8 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.10 PVD20734.1 - 0.00032 20.8 11.8 2.1 8.6 0.0 7.0 2 2 4 8 8 8 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) VPS13_C PF16909.5 PVD20734.1 - 0.0013 18.5 8.5 5.5 6.7 0.2 4.9 2 1 4 6 6 6 1 Vacuolar-sorting-associated 13 protein C-terminal SF-assemblin PF06705.11 PVD20734.1 - 0.0014 18.1 1.4 0.17 11.2 0.0 2.7 1 1 1 2 2 2 1 SF-assemblin/beta giardin DUF1664 PF07889.12 PVD20734.1 - 0.0029 17.6 8.4 0.16 12.0 0.3 3.4 2 2 0 3 3 3 2 Protein of unknown function (DUF1664) GrpE PF01025.19 PVD20734.1 - 0.0036 17.0 4.5 0.22 11.1 0.3 3.7 1 1 3 4 4 4 1 GrpE DUF948 PF06103.11 PVD20734.1 - 0.0041 17.3 19.6 5.6 7.3 0.8 5.2 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 PVD20734.1 - 0.0067 14.5 2.7 0.12 10.3 0.1 2.7 2 1 0 3 3 3 1 Prominin Peptidase_S64 PF08192.11 PVD20734.1 - 0.02 13.4 1.1 1.5 7.2 0.3 2.8 1 1 1 2 2 2 0 Peptidase family S64 EzrA PF06160.12 PVD20734.1 - 0.038 12.2 0.0 0.49 8.5 0.0 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ATG_C PF09333.11 PVD20734.1 - 0.066 13.6 6.8 56 4.2 0.0 5.7 1 1 5 7 7 7 0 Autophagy-related protein C terminal domain BAR_3_WASP_bdg PF10456.9 PVD20734.1 - 0.068 12.6 0.2 0.27 10.7 0.0 2.0 2 1 0 2 2 2 0 WASP-binding domain of Sorting nexin protein PhaP_Bmeg PF09602.10 PVD20734.1 - 0.11 12.5 0.0 2.2 8.2 0.0 2.4 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF883 PF05957.13 PVD20734.1 - 0.13 12.9 7.3 51 4.6 0.0 4.7 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.12 PVD20734.1 - 0.14 12.2 14.4 0.28 11.2 0.4 4.0 2 1 2 4 4 4 0 Laminin Domain II BORCS6 PF10157.9 PVD20734.1 - 0.34 11.1 9.1 7.5 6.8 0.5 4.0 1 1 4 5 5 5 0 BLOC-1-related complex sub-unit 6 Phasin_2 PF09361.10 PVD20734.1 - 0.41 10.9 6.4 1.3 9.3 0.4 3.9 2 2 3 5 5 5 0 Phasin protein Fibin PF15819.5 PVD20734.1 - 0.5 10.1 2.0 28 4.4 0.1 3.1 1 1 1 3 3 3 0 Fin bud initiation factor homologue Focal_AT PF03623.13 PVD20734.1 - 1.4 8.9 7.9 21 5.1 0.3 4.0 2 1 2 5 5 4 0 Focal adhesion targeting region RRF PF01765.19 PVD20734.1 - 1.7 8.5 3.8 25 4.8 0.3 3.2 1 1 2 3 3 3 0 Ribosome recycling factor Phage_terminase PF10668.9 PVD20734.1 - 7 6.7 5.5 91 3.2 0.0 4.1 3 2 2 5 5 5 0 Phage terminase small subunit Rx_N PF18052.1 PVD20734.1 - 8.1 6.8 12.5 49 4.3 0.1 5.4 3 2 2 5 5 5 0 Rx N-terminal domain CLTH PF10607.9 PVD20735.1 - 3.7e-45 153.5 0.0 5.9e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 PVD20735.1 - 2.8e-20 72.6 0.7 6.8e-20 71.4 0.7 1.7 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 PVD20735.1 - 1.9e-06 27.6 0.0 7.4e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 LisH THRAP3_BCLAF1 PF15440.6 PVD20735.1 - 1.4 7.9 13.7 0.77 8.7 11.4 1.3 1 1 0 1 1 1 0 THRAP3/BCLAF1 family TSNAXIP1_N PF15739.5 PVD20736.1 - 1e-30 106.4 14.2 1.2e-29 102.9 4.3 3.2 2 1 1 3 3 3 2 Translin-associated factor X-interacting N-terminus DUF1251 PF06856.11 PVD20736.1 - 0.021 14.5 0.9 0.14 11.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1251) EFhand_Ca_insen PF08726.10 PVD20736.1 - 0.087 12.9 0.7 29 4.8 0.1 3.8 3 1 0 3 3 3 0 Ca2+ insensitive EF hand Sec34 PF04136.15 PVD20736.1 - 0.15 12.0 10.7 0.12 12.3 0.3 3.4 2 1 1 3 3 3 0 Sec34-like family DUF4600 PF15372.6 PVD20736.1 - 0.26 11.7 17.1 0.44 11.0 11.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4407 PF14362.6 PVD20736.1 - 0.63 9.3 12.8 0.077 12.3 8.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 PVD20736.1 - 1 9.6 11.0 4.4 7.6 0.7 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper AA_permease_2 PF13520.6 PVD20737.1 - 8.3e-44 150.1 37.6 3.8e-29 101.8 16.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 PVD20737.1 - 5.9e-25 87.8 29.3 2.8e-17 62.5 10.6 2.1 2 0 0 2 2 2 2 Amino acid permease 7tm_1 PF00001.21 PVD20739.1 - 1.3e-20 73.8 13.4 1.7e-20 73.5 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD20739.1 - 6.7e-08 32.2 11.7 1.2e-07 31.3 11.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD20739.1 - 2.4e-05 24.1 4.9 2.4e-05 24.1 4.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TPR_1 PF00515.28 PVD20740.1 - 1.6e-39 132.1 3.8 6.4e-06 25.8 0.0 8.6 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 PVD20740.1 - 4.8e-39 129.3 9.0 0.00013 21.8 0.4 9.8 11 0 0 11 11 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 PVD20740.1 - 1.4e-34 115.4 0.7 1.1e-05 25.2 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 PVD20740.1 - 7.5e-24 83.1 0.1 2.4e-06 27.1 0.0 7.2 5 2 2 7 7 7 5 TPR repeat TPR_19 PF14559.6 PVD20740.1 - 8.8e-21 74.2 5.8 8.5e-06 26.2 0.0 6.0 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 PVD20740.1 - 1.3e-20 73.8 0.2 0.00025 21.6 0.0 5.9 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 PVD20740.1 - 1.9e-19 69.6 0.9 0.0002 21.4 0.0 6.3 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 PVD20740.1 - 1e-18 67.4 17.1 0.00055 20.2 0.2 6.7 4 3 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 PVD20740.1 - 4.3e-18 64.5 3.9 0.0019 18.9 0.0 7.8 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 PVD20740.1 - 9.2e-15 53.5 4.5 0.011 15.7 0.0 7.9 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 PVD20740.1 - 3e-12 46.0 9.8 0.00021 21.4 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD20740.1 - 4.2e-12 46.1 18.3 0.00079 19.6 2.2 6.0 2 2 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PVD20740.1 - 1.1e-08 34.7 1.0 0.0026 17.0 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD20740.1 - 8.3e-08 32.4 7.0 7.1 7.5 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat NARP1 PF12569.8 PVD20740.1 - 1.6e-07 30.7 0.5 0.0004 19.4 0.0 3.1 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 PVD20740.1 - 4.3e-07 30.2 1.4 0.0011 19.2 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD20740.1 - 7.7e-07 28.8 3.1 0.12 11.8 0.4 3.5 2 1 0 3 3 3 2 Coatomer epsilon subunit BTAD PF03704.17 PVD20740.1 - 0.00021 21.8 3.4 0.43 11.0 0.1 3.8 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 PVD20740.1 - 0.00026 20.7 12.7 3.1 7.8 0.0 6.8 5 1 1 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 PVD20740.1 - 0.0017 17.4 1.1 0.45 9.4 0.0 3.0 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 PVD20740.1 - 0.0037 16.7 8.8 0.21 10.9 0.1 3.5 2 1 1 3 3 3 1 MalT-like TPR region PknG_TPR PF16918.5 PVD20740.1 - 0.0061 15.3 0.4 1.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat Wzy_C_2 PF11846.8 PVD20740.1 - 0.0066 16.4 5.2 0.83 9.5 0.0 3.2 3 1 0 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal ComR_TPR PF18710.1 PVD20740.1 - 0.026 14.1 0.4 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 ComR tetratricopeptide DUF4919 PF16266.5 PVD20740.1 - 0.029 14.3 0.2 2.6 8.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) HrpB1_HrpK PF09613.10 PVD20740.1 - 0.035 13.7 0.2 15 5.3 0.0 3.2 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4810 PF16068.5 PVD20740.1 - 0.051 14.1 0.3 5.2 7.7 0.0 3.4 3 1 0 3 3 2 0 Domain of unknown function (DUF4810) TPR_21 PF09976.9 PVD20740.1 - 0.15 11.8 0.3 25 4.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain DUF2989 PF11207.8 PVD20740.1 - 0.19 11.4 2.5 1.2 8.8 0.2 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2989) MIT PF04212.18 PVD20740.1 - 0.3 11.2 2.7 1.3e+02 2.7 0.1 5.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Paf67 PF10255.9 PVD20740.1 - 2.6 7.0 5.3 7.2 5.5 0.1 2.7 3 1 0 3 3 3 0 RNA polymerase I-associated factor PAF67 DUF3140 PF11338.8 PVD20741.1 - 0.85 10.1 5.9 10 6.6 5.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) CTP_transf_like PF01467.26 PVD20742.1 - 6.3e-10 39.4 0.0 2.9e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 PVD20742.1 - 0.0035 17.2 0.1 0.025 14.5 0.1 2.1 2 0 0 2 2 2 1 FAD synthetase CDP-OH_P_transf PF01066.21 PVD20742.1 - 0.2 12.4 0.2 0.2 12.4 0.2 2.3 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase PBP_like_2 PF12849.7 PVD20743.1 - 1.4e-10 41.3 0.1 1.8e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 PVD20744.1 - 1.7e-13 50.9 0.1 2.5e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 PBP superfamily domain TNFR_16_TM PF18422.1 PVD20744.1 - 0.13 12.3 1.4 0.25 11.3 1.4 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Pkinase_Tyr PF07714.17 PVD20745.1 - 1.3e-31 109.8 0.0 3.1e-31 108.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD20745.1 - 9.3e-17 61.2 0.0 3.6e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF4543 PF15076.6 PVD20745.1 - 0.15 12.2 0.3 2.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Na_H_Exchanger PF00999.21 PVD20747.1 - 1.8e-28 99.4 32.1 2.9e-28 98.7 32.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 PVD20747.1 - 5.2e-09 36.0 0.0 1.5e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF5592 PF17332.2 PVD20747.1 - 0.86 10.2 0.0 0.86 10.2 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5592) Prefoldin PF02996.17 PVD20748.1 - 2.7e-19 69.3 0.1 2.7e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit CAP PF00188.26 PVD20748.1 - 3.3e-11 44.1 2.0 6.9e-11 43.1 2.0 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Prefoldin_3 PF13758.6 PVD20748.1 - 0.00024 21.1 0.1 0.0019 18.2 0.0 2.7 2 1 1 3 3 3 1 Prefoldin subunit CENP-B_dimeris PF09026.10 PVD20748.1 - 0.38 11.2 6.1 1.2 9.5 6.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CAP PF00188.26 PVD20749.1 - 1.5e-13 51.7 1.9 3e-13 50.7 1.9 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 PVD20750.1 - 1.2e-10 42.3 0.6 1.7e-10 41.8 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TRAPPC-Trs85 PF12739.7 PVD20752.1 - 1.8e-129 432.3 0.8 2.6e-129 431.8 0.8 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 PVD20752.1 - 0.045 13.2 1.5 0.1 12.0 1.5 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TRAPPC9-Trs120 PF08626.11 PVD20752.1 - 0.11 9.8 0.1 0.19 9.0 0.1 1.3 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit MIP PF00230.20 PVD20754.1 - 4.9e-58 196.5 7.4 5.8e-58 196.3 7.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein SNF PF00209.18 PVD20756.1 - 3e-162 541.0 36.1 9.7e-95 318.2 11.3 3.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Ldl_recept_a PF00057.18 PVD20757.1 - 5.7e-11 42.4 23.1 1.8e-06 28.1 6.3 2.9 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A zf-RING_2 PF13639.6 PVD20759.1 - 3.2e-12 46.6 6.6 7.4e-12 45.4 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain CUE PF02845.16 PVD20759.1 - 1.5e-09 37.4 0.1 5.1e-09 35.7 0.1 2.0 1 0 0 1 1 1 1 CUE domain zf-C3HC4_2 PF13923.6 PVD20759.1 - 5.1e-09 35.8 5.7 9.5e-09 35.0 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD20759.1 - 2.9e-08 33.4 4.5 5.1e-08 32.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD20759.1 - 1.8e-07 30.9 2.8 3e-07 30.2 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD20759.1 - 2.2e-07 30.8 1.6 4.4e-07 29.8 1.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD20759.1 - 1e-06 28.9 9.7 3.7e-06 27.1 8.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD20759.1 - 3.2e-06 26.8 1.1 3.2e-06 26.8 1.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 PVD20759.1 - 5.7e-06 26.2 3.2 9.5e-06 25.5 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD20759.1 - 8.6e-06 25.5 3.8 1.5e-05 24.7 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PVD20759.1 - 6.4e-05 22.5 4.1 0.00014 21.4 4.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type G2BR PF18442.1 PVD20759.1 - 0.00019 21.0 6.2 0.00019 21.0 6.2 2.5 2 0 0 2 2 2 1 E3 gp78 Ube2g2-binding region (G2BR) zf-ANAPC11 PF12861.7 PVD20759.1 - 0.0002 21.3 1.1 0.00057 19.9 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PVD20759.1 - 0.044 14.0 3.5 0.083 13.1 3.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 PVD20759.1 - 0.42 10.8 5.1 1.2 9.4 5.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 PVD20759.1 - 0.47 10.3 2.7 1.3 8.9 2.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 PVD20759.1 - 0.57 10.4 7.4 1.2 9.3 7.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PVD20759.1 - 1.5 8.9 3.3 3.4 7.8 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger DAD PF02109.16 PVD20760.1 - 7.9e-48 161.3 2.3 8.7e-48 161.2 2.3 1.0 1 0 0 1 1 1 1 DAD family zf-C2H2 PF00096.26 PVD20761.1 - 1.9e-17 62.7 133.5 0.0039 17.6 0.8 17.8 19 0 0 19 19 19 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20761.1 - 2.2e-16 59.1 126.8 0.021 15.6 1.8 19.0 19 0 0 19 19 19 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD20761.1 - 7.4e-13 48.0 119.1 7e-07 28.9 0.9 15.5 16 0 0 16 16 16 10 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD20761.1 - 1.2e-11 44.5 86.3 0.0022 18.3 0.4 15.6 17 0 0 17 17 17 7 Zinc-finger double domain zf-C2H2_2 PF12756.7 PVD20761.1 - 3.1e-07 30.7 81.1 0.18 12.2 0.1 15.7 8 4 8 16 16 16 6 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 PVD20761.1 - 0.0004 20.8 55.3 0.031 14.7 0.1 11.0 9 2 1 10 10 10 4 C2HE / C2H2 / C2HC zinc-binding finger HydF_tetramer PF18133.1 PVD20761.1 - 0.0047 16.7 0.4 0.016 14.9 0.4 1.9 1 0 0 1 1 1 1 Hydrogen maturase F tetramerization domain UQ_con PF00179.26 PVD20762.1 - 2.1e-38 131.1 0.0 2.6e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PVD20762.1 - 0.00072 19.8 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 RWD domain DUF2378 PF09536.10 PVD20765.1 - 0.0097 15.8 0.0 0.89 9.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2378) Senescence PF06911.12 PVD20765.1 - 0.046 14.0 0.1 0.09 13.1 0.1 1.4 1 0 0 1 1 1 0 Senescence-associated protein VBS PF08913.10 PVD20765.1 - 0.048 14.1 0.2 7.7 7.0 0.0 2.7 1 1 1 2 2 2 0 Vinculin Binding Site Baculo_PEP_C PF04513.12 PVD20765.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EspB PF05802.11 PVD20765.1 - 0.1 12.6 0.3 0.16 12.0 0.3 1.5 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF2729 PF10870.8 PVD20765.1 - 0.46 10.4 4.5 9.2 6.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Tape_meas_lam_C PF09718.10 PVD20766.1 - 0.02 15.0 0.3 0.43 10.8 0.3 2.6 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Senescence PF06911.12 PVD20766.1 - 0.035 14.4 3.9 0.72 10.1 0.3 2.4 1 1 1 2 2 2 0 Senescence-associated protein ApoLp-III PF07464.11 PVD20766.1 - 0.062 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 PVD20766.1 - 0.071 13.0 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5324 PF17258.2 PVD20766.1 - 1.9 8.1 8.1 11 5.6 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5324) 7tm_1 PF00001.21 PVD20768.1 - 3e-26 92.3 3.0 4.2e-26 91.8 3.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD20768.1 - 1.3e-05 24.7 0.9 2.2e-05 24.0 0.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD20768.1 - 5.4e-05 22.9 1.6 0.0001 22.1 1.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD20769.1 - 1.1e-10 41.3 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_92 PF01697.27 PVD20770.1 - 5.8e-44 150.7 0.3 7.2e-44 150.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD20770.1 - 0.00012 22.6 0.1 0.00023 21.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Helicase_C PF00271.31 PVD20772.1 - 1.5e-20 73.6 0.0 2.2e-15 57.0 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 PVD20772.1 - 7.9e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Drc1-Sld2 PF11719.8 PVD20772.1 - 2e-11 44.2 3.8 2e-11 44.2 3.8 2.3 2 0 0 2 2 2 2 DNA replication and checkpoint protein zf-CCHC PF00098.23 PVD20772.1 - 5e-06 26.3 2.9 2.1e-05 24.4 2.9 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD20772.1 - 0.005 16.6 3.4 0.013 15.3 3.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Mod_r PF07200.13 PVD20772.1 - 0.17 11.9 4.1 0.12 12.4 1.0 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf-CCHC_5 PF14787.6 PVD20772.1 - 6.8 6.5 10.7 0.19 11.5 3.9 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PMP22_Claudin PF00822.20 PVD20775.1 - 1.3e-11 44.6 15.7 1.7e-11 44.3 15.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD20775.1 - 5.6e-07 29.5 10.7 5.6e-07 29.5 10.7 2.5 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.12 PVD20775.1 - 1.2 9.3 11.3 0.1 12.8 4.1 2.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Pkinase_Tyr PF07714.17 PVD20776.1 - 5e-47 160.3 0.0 6.3e-24 84.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD20776.1 - 1.5e-36 126.2 0.0 1.7e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PVD20776.1 - 0.069 12.5 0.3 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phospholip_A2_2 PF05826.12 PVD20777.1 - 9.1e-13 48.2 0.6 2e-12 47.1 0.6 1.6 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 PVD20778.1 - 5.5e-29 100.2 10.2 2e-14 53.6 0.9 3.0 3 0 0 3 3 3 2 Phospholipase A2 Phospholip_A2_1 PF00068.19 PVD20778.1 - 3.5e-05 24.2 5.7 0.072 13.6 1.0 2.5 2 0 0 2 2 2 2 Phospholipase A2 Shisa PF13908.6 PVD20779.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.9 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator PRIMA1 PF16101.5 PVD20779.1 - 1.2 9.2 4.3 3 7.9 1.3 2.7 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 Carb_anhydrase PF00194.21 PVD20782.1 - 9e-37 127.0 0.4 7.8e-26 91.1 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase PI-PLC-X PF00388.19 PVD20783.1 - 6.2e-60 201.0 0.0 1.2e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 PVD20783.1 - 7.9e-42 141.2 2.0 2.9e-21 75.3 0.4 2.6 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 PVD20783.1 - 3.7e-37 127.2 0.0 1.1e-36 125.6 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 PVD20783.1 - 9.2e-17 61.2 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 PVD20783.1 - 8.6e-16 57.3 0.2 2.7e-15 55.7 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD20783.1 - 2.4e-11 43.3 0.6 7e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 PVD20783.1 - 1.6e-09 38.2 0.0 0.0074 16.8 0.0 3.7 3 0 0 3 3 3 3 PH domain SH3_2 PF07653.17 PVD20783.1 - 5.1e-08 32.5 0.1 1.1e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_12 PF16457.5 PVD20783.1 - 5.6e-05 23.7 0.1 0.00022 21.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain COesterase PF00135.28 PVD20784.1 - 3.4e-118 395.7 0.0 4.7e-118 395.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD20784.1 - 1.5e-06 28.2 1.5 1.4e-05 25.1 0.7 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4388 PF14332.6 PVD20784.1 - 0.04 14.2 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4388) Trypsin PF00089.26 PVD20785.1 - 5e-56 190.0 1.8 5.6e-56 189.8 1.8 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD20785.1 - 6.5e-05 23.9 0.2 0.00015 22.7 0.2 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PVD20786.1 - 8.5e-54 182.7 6.1 8.5e-54 182.7 6.1 1.9 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 PVD20786.1 - 0.064 13.6 0.1 0.25 11.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) SOG2 PF10428.9 PVD20786.1 - 0.83 8.8 14.5 1.1 8.3 14.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1731 PF08338.11 PVD20787.1 - 6.9e-17 61.0 0.0 1.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 PVD20787.1 - 2.2e-11 43.7 0.0 1.7e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD20787.1 - 0.00077 19.0 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PVD20787.1 - 0.0011 18.9 0.0 0.0051 16.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 PVD20787.1 - 0.045 13.7 0.2 0.39 10.6 0.2 2.1 1 1 1 2 2 2 0 KR domain adh_short PF00106.25 PVD20787.1 - 0.062 12.7 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 PVD20787.1 - 0.082 12.0 0.1 0.26 10.3 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain NmrA PF05368.13 PVD20787.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Adaptin_N PF01602.20 PVD20788.1 - 8.7e-146 486.5 9.8 1.2e-145 486.1 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 PVD20788.1 - 7.7e-27 93.8 2.4 9.6e-27 93.5 1.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 PVD20788.1 - 3.4e-13 50.0 9.9 1.6e-08 34.7 0.8 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Kinetochor_Ybp2 PF08568.10 PVD20788.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin CLASP_N PF12348.8 PVD20788.1 - 0.088 12.4 6.5 3 7.3 1.0 3.5 3 1 0 3 3 3 0 CLASP N terminal Eno-Rase_FAD_bd PF07055.12 PVD20789.1 - 0.013 15.9 1.1 0.11 12.9 1.1 2.7 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain YvrJ PF12841.7 PVD20789.1 - 0.038 13.5 0.9 0.78 9.3 0.3 3.1 2 0 0 2 2 2 0 YvrJ protein family LRR_4 PF12799.7 PVD20790.1 - 2.5e-14 53.1 23.9 2.5e-07 30.9 2.9 4.3 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD20790.1 - 2.4e-11 43.2 25.2 7.2e-06 25.7 3.6 3.9 3 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 PVD20790.1 - 1.7e-08 34.2 2.7 0.00031 20.3 1.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PVD20790.1 - 1.9e-06 27.4 15.9 0.27 11.4 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 PVD20790.1 - 0.16 12.6 18.1 14 6.7 0.2 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_2 PF07723.13 PVD20790.1 - 0.5 11.1 5.0 12 6.8 0.0 3.6 3 1 1 4 4 4 0 Leucine Rich Repeat Kinesin PF00225.23 PVD20791.1 - 3.6e-99 331.8 1.9 3.6e-99 331.8 1.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD20791.1 - 2.5e-21 76.2 0.5 1.1e-20 74.1 0.1 2.3 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 PVD20791.1 - 5.7e-08 33.1 3.3 1.5e-07 31.7 1.2 2.7 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 PVD20791.1 - 1.6e-07 31.5 0.0 5.7e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 PVD20791.1 - 9e-06 26.0 20.7 0.0013 18.9 1.1 4.5 3 1 1 4 4 4 2 Kinesin-associated Yop-YscD_cpl PF16697.5 PVD20791.1 - 0.00026 21.3 0.0 0.00097 19.4 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RPA_interact_M PF14767.6 PVD20791.1 - 4.7 7.8 6.2 2.2 8.9 2.8 2.3 2 0 0 2 2 2 0 Replication protein A interacting middle E2F_CC-MB PF16421.5 PVD20792.1 - 5.9e-32 109.9 0.0 9.9e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 PVD20792.1 - 4.8e-24 84.2 0.2 9.2e-24 83.3 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain BACK PF07707.15 PVD20793.1 - 1.3e-15 57.4 5.2 1.8e-13 50.4 3.5 3.0 2 1 0 2 2 2 2 BTB And C-terminal Kelch BTB PF00651.31 PVD20793.1 - 3.1e-06 27.4 0.0 8.4e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain MARVEL PF01284.23 PVD20794.1 - 2.1e-10 40.8 17.5 2.9e-10 40.4 17.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Trp_oprn_chp PF09534.10 PVD20794.1 - 0.04 13.7 1.4 0.097 12.5 1.4 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ERGIC_N PF13850.6 PVD20794.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Vac14_Fig4_bd PF11916.8 PVD20795.1 - 2.1e-74 249.1 10.0 2.1e-74 249.1 10.0 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 PVD20795.1 - 1.7e-41 140.7 0.2 1.4e-37 128.2 0.0 3.8 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 PVD20795.1 - 0.00063 19.8 3.3 0.58 10.6 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 PVD20795.1 - 0.01 16.3 1.1 3.7 8.1 0.0 4.8 7 0 0 7 7 7 0 HEAT-like repeat IMD PF08397.11 PVD20796.1 - 2.4e-81 272.3 3.5 3.1e-81 271.9 3.5 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain RmuC PF02646.16 PVD20796.1 - 0.027 13.6 3.0 0.029 13.5 1.2 1.8 2 0 0 2 2 2 0 RmuC family PXA PF02194.15 PVD20796.1 - 0.058 13.4 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 PXA domain SF-assemblin PF06705.11 PVD20796.1 - 0.067 12.5 1.8 0.1 11.9 1.8 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin MscS_porin PF12795.7 PVD20796.1 - 0.079 12.5 2.2 0.13 11.8 2.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Carbpep_Y_N PF05388.11 PVD20796.1 - 0.12 12.9 2.5 0.19 12.2 1.3 2.0 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide DUF4200 PF13863.6 PVD20797.1 - 0.55 10.6 10.0 1.4 9.3 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-C2H2 PF00096.26 PVD20798.1 - 9.5e-110 353.3 269.3 1.4e-05 25.3 2.3 28.7 28 0 0 28 28 28 28 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD20798.1 - 2.1e-104 337.7 225.7 2e-08 34.3 0.8 31.3 31 0 0 31 31 31 26 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD20798.1 - 4.5e-82 263.5 254.6 0.00042 20.9 0.6 28.9 29 0 0 29 29 29 27 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD20798.1 - 1.2e-46 156.1 178.1 0.00079 19.6 2.6 27.6 28 0 0 28 28 28 20 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD20798.1 - 6.5e-25 86.6 206.0 0.0019 18.2 0.2 27.6 28 0 0 28 28 28 19 C2H2-type zinc finger zf-met PF12874.7 PVD20798.1 - 6.4e-22 77.2 199.4 0.0013 19.1 0.9 25.4 27 0 0 27 27 27 15 Zinc-finger of C2H2 type zf-C2HE PF16278.5 PVD20798.1 - 7.8e-07 29.5 180.7 0.016 15.6 0.7 25.3 11 10 15 26 26 26 9 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 PVD20798.1 - 1.1e-06 28.8 182.4 0.19 12.1 6.2 24.8 6 6 15 22 22 22 8 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 PVD20798.1 - 0.0012 18.7 0.8 0.0012 18.7 0.8 13.1 12 2 2 14 14 13 2 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 PVD20798.1 - 0.0047 16.6 0.3 0.0047 16.6 0.3 22.4 25 0 0 25 25 24 8 zinc-finger C2H2-type TerY_C PF15616.6 PVD20798.1 - 0.012 15.8 0.1 0.012 15.8 0.1 5.7 7 0 0 7 7 7 0 TerY-C metal binding domain GAGA PF09237.11 PVD20798.1 - 2.7 7.8 52.9 0.033 14.0 0.4 12.1 10 3 3 14 14 14 0 GAGA factor zf-C2H2 PF00096.26 PVD20799.1 - 1.8e-05 24.9 23.7 0.0081 16.6 0.4 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 PVD20799.1 - 0.00028 21.2 20.2 0.0089 16.4 10.2 4.5 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 PVD20799.1 - 0.0042 16.8 8.9 0.49 10.2 0.4 3.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-CpG_bind_C PF12269.8 PVD20799.1 - 0.026 14.3 0.2 0.026 14.3 0.2 2.7 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-C2H2_4 PF13894.6 PVD20799.1 - 0.21 12.5 0.0 0.13 13.1 4.3 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2HE PF16278.5 PVD20799.1 - 0.4 11.2 6.4 0.76 10.3 0.1 3.7 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 PVD20801.1 - 8.1e-09 35.5 32.3 3.4e-05 24.0 0.5 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD20801.1 - 9.8e-05 22.6 29.4 0.0039 17.5 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD20801.1 - 0.0026 18.1 45.5 0.047 14.0 0.6 6.2 3 1 3 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 PVD20801.1 - 0.013 15.2 0.8 0.013 15.2 0.8 4.8 5 0 0 5 5 5 0 U1 zinc finger zf-C2HE PF16278.5 PVD20801.1 - 0.025 15.0 0.6 0.025 15.0 0.6 4.3 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 PVD20801.1 - 0.16 12.5 0.2 0.16 12.5 0.2 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type AKAP95 PF04988.12 PVD20801.1 - 2.4 8.4 31.1 4.3 7.5 6.5 4.8 4 2 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 PVD20802.1 - 0.017 15.4 2.1 0.017 15.4 2.1 4.0 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD20802.1 - 0.22 12.5 22.3 0.39 11.7 3.6 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 PVD20802.1 - 4.5 7.0 11.7 9 6.0 0.1 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 PVD20803.1 - 8.8e-23 79.7 51.2 1e-06 28.8 3.6 7.6 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD20803.1 - 2.4e-15 55.9 56.5 0.00017 22.1 0.6 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD20803.1 - 1.6e-09 37.7 65.4 0.013 15.9 0.9 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD20803.1 - 4.6e-07 29.5 41.2 8.8e-06 25.4 1.2 6.5 6 0 0 6 6 6 4 C2H2-type zinc-finger domain BolA PF01722.18 PVD20803.1 - 0.036 14.4 1.8 0.24 11.7 0.2 2.9 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_6 PF13912.6 PVD20803.1 - 0.15 12.1 0.3 0.15 12.1 0.3 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PVD20803.1 - 0.18 11.8 23.4 0.21 11.5 0.2 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 PVD20803.1 - 2.2 8.7 36.4 0.59 10.5 1.4 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 PVD20803.1 - 2.9 8.0 25.3 5 7.3 3.0 5.2 3 2 2 5 5 5 0 Zinc-finger Ank_2 PF12796.7 PVD20805.1 - 6.4e-51 170.9 11.0 1e-13 51.6 0.3 7.4 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 PVD20805.1 - 1.4e-44 148.6 18.4 2.8e-06 27.5 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 PVD20805.1 - 1.1e-43 146.7 15.5 1.7e-10 40.9 0.2 9.8 3 3 8 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD20805.1 - 3.9e-42 142.1 7.5 8.5e-08 32.6 0.0 9.9 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20805.1 - 5.5e-40 130.8 19.7 0.00018 21.7 0.0 12.5 14 0 0 14 14 14 8 Ankyrin repeat PK_C PF02887.16 PVD20805.1 - 0.0062 16.8 0.1 12 6.2 0.0 3.8 2 1 2 4 4 4 1 Pyruvate kinase, alpha/beta domain DUF4716 PF15837.5 PVD20806.1 - 0.28 11.3 3.4 0.76 9.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) Ras PF00071.22 PVD20807.1 - 3.2e-16 59.3 0.1 4e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 PVD20807.1 - 0.0038 17.1 0.1 0.0045 16.9 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase RGS12_usC PF16612.5 PVD20807.1 - 0.062 13.7 1.9 0.09 13.2 1.9 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 GTP_EFTU PF00009.27 PVD20807.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Alpha_kinase PF02816.18 PVD20808.1 - 3e-23 82.9 0.0 3.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family ABC1 PF03109.16 PVD20808.1 - 0.2 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 ABC1 family DUF4435 PF14491.6 PVD20809.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) CODH_A_N PF18537.1 PVD20809.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain HMG_box PF00505.19 PVD20810.1 - 4.3e-15 55.9 0.2 7.9e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD20810.1 - 5.1e-10 39.8 0.3 1e-09 38.8 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain AA_permease PF00324.21 PVD20812.1 - 5.7e-61 206.6 38.8 1.5e-42 145.9 4.8 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 PVD20812.1 - 7.4e-32 110.9 1.3 7.5e-14 51.6 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 PVD20812.1 - 2.2e-20 72.9 43.7 1.1e-17 64.1 13.0 2.1 2 0 0 2 2 2 2 Amino acid permease LRR_4 PF12799.7 PVD20813.1 - 4.7e-18 65.0 53.2 0.0034 17.7 0.4 11.4 5 3 5 11 11 11 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD20813.1 - 8.1e-15 53.5 64.0 0.3 11.3 0.2 16.8 18 0 0 18 18 18 8 Leucine Rich repeat LRR_1 PF00560.33 PVD20813.1 - 4.1e-07 29.6 47.5 0.49 11.1 1.4 13.2 13 2 1 14 14 14 3 Leucine Rich Repeat LRR_8 PF13855.6 PVD20813.1 - 4.7e-07 29.5 46.1 0.042 13.6 0.4 10.0 9 4 1 10 10 10 5 Leucine rich repeat F-box-like PF12937.7 PVD20813.1 - 1.2e-05 25.1 0.0 5e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD20813.1 - 0.00048 19.9 6.7 0.00064 19.5 0.0 4.0 4 0 0 4 4 4 1 F-box domain F-box_5 PF18511.1 PVD20813.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box LRR_2 PF07723.13 PVD20813.1 - 3.3 8.5 0.0 3.3 8.5 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich Repeat Lon_C PF05362.13 PVD20814.1 - 6.8e-84 280.5 0.3 1.2e-83 279.7 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 PVD20814.1 - 1e-22 81.0 0.0 3.9e-22 79.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 PVD20814.1 - 1.2e-18 67.8 0.1 3e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 PVD20814.1 - 7e-10 39.1 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 PVD20814.1 - 8.7e-06 25.6 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 PVD20814.1 - 0.0001 22.7 1.4 0.00035 21.0 0.0 2.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 PVD20814.1 - 0.00031 21.0 0.2 0.005 17.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 PVD20814.1 - 0.0004 20.5 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 PVD20814.1 - 0.00046 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PVD20814.1 - 0.0014 18.6 0.1 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Pex19 PF04614.12 PVD20814.1 - 0.0033 17.2 0.2 0.0065 16.3 0.2 1.4 1 0 0 1 1 1 1 Pex19 protein family AAA_PrkA PF08298.11 PVD20814.1 - 0.0036 16.3 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 PVD20814.1 - 0.005 16.6 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 PVD20814.1 - 0.023 13.9 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 PVD20814.1 - 0.026 15.1 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 PVD20814.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.22 PVD20814.1 - 0.088 13.2 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 1 0 RNA helicase Neur_chan_LBD PF02931.23 PVD20815.1 - 5.2e-36 124.1 0.0 7.8e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD20815.1 - 2.5e-33 116.1 0.0 4.3e-33 115.3 0.0 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COG7 PF10191.9 PVD20816.1 - 1.5e-203 678.3 29.3 1.1e-202 675.4 29.3 2.0 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) Prominin PF05478.11 PVD20816.1 - 0.017 13.1 11.4 0.028 12.4 10.5 1.8 2 0 0 2 2 2 0 Prominin COG5 PF10392.9 PVD20816.1 - 0.031 14.5 18.4 0.025 14.8 4.0 4.3 4 1 1 5 5 5 0 Golgi transport complex subunit 5 RdRP_4 PF02123.16 PVD20816.1 - 0.045 12.6 5.6 0.046 12.6 3.7 1.9 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase DUF3303 PF11746.8 PVD20816.1 - 0.08 13.2 1.2 4.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3303) Sec5 PF15469.6 PVD20816.1 - 0.45 10.3 8.7 5.7 6.7 0.3 3.1 3 0 0 3 3 3 0 Exocyst complex component Sec5 CHDCT2 PF08074.11 PVD20816.1 - 0.57 10.3 5.4 0.32 11.1 2.1 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Spectrin_like PF18373.1 PVD20816.1 - 1.2 9.2 7.9 5.6 7.1 0.0 3.6 2 1 1 3 3 3 0 Spectrin like domain Exonuc_VII_L PF02601.15 PVD20816.1 - 4.7 6.7 12.4 2.5 7.6 8.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF148 PF02520.17 PVD20816.1 - 5.7 7.1 12.8 48 4.1 8.2 3.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 tRNA-synt_1 PF00133.22 PVD20819.1 - 3e-45 154.6 0.5 2.7e-24 85.4 2.3 6.2 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PVD20819.1 - 2.7e-31 108.7 0.3 7.8e-23 80.8 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PVD20819.1 - 4.2e-16 59.0 0.0 2.7e-09 36.8 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 PVD20819.1 - 4.5e-07 29.9 0.1 1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PVD20819.1 - 0.0052 16.2 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain CBM_14 PF01607.24 PVD20820.1 - 1.5e-11 44.3 1.2 2.6e-11 43.5 1.2 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ras PF00071.22 PVD20821.1 - 1.4e-19 70.3 0.1 2e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 PVD20821.1 - 0.013 15.5 0.3 0.044 13.8 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 PVD20821.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 PVD20821.1 - 0.14 11.6 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 PVD20823.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20823.1 - 0.0085 16.3 0.1 0.026 14.7 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 PVD20823.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 PVD20823.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain zf-C2H2 PF00096.26 PVD20824.1 - 6.7e-25 86.1 34.3 6.7e-06 26.3 0.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20824.1 - 6.2e-20 70.2 30.6 0.00048 20.7 0.5 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD20824.1 - 2.4e-17 62.5 28.5 1.6e-06 28.3 0.3 5.6 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD20824.1 - 8.2e-09 35.5 20.7 0.061 13.6 0.1 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD20824.1 - 3.8e-08 33.4 25.4 0.042 14.3 0.6 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD20824.1 - 4.1e-07 29.8 33.1 0.01 15.8 1.8 5.7 5 1 0 5 5 5 4 C2H2-type zinc finger zf_UBZ PF18439.1 PVD20824.1 - 6.3e-05 22.5 11.3 1 9.0 0.1 5.3 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger TFIIA PF03153.13 PVD20824.1 - 0.0012 18.9 3.5 0.0015 18.6 3.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-Di19 PF05605.12 PVD20824.1 - 0.0012 19.1 19.9 0.19 12.1 4.5 4.4 1 1 3 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD20824.1 - 0.0013 18.4 25.7 0.12 12.1 0.6 5.3 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-BED PF02892.15 PVD20824.1 - 0.0042 17.1 25.9 0.055 13.5 0.6 5.2 1 1 4 5 5 5 2 BED zinc finger HypA PF01155.19 PVD20824.1 - 0.0061 16.6 10.7 0.84 9.7 1.2 3.4 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 PVD20824.1 - 0.0084 16.2 14.6 0.42 10.8 2.6 3.8 3 2 0 3 3 3 2 Zinc ribbon domain XPA_N PF01286.18 PVD20824.1 - 0.014 15.4 17.2 3.2 7.9 1.6 5.0 5 0 0 5 5 5 0 XPA protein N-terminal zf-AN1 PF01428.16 PVD20824.1 - 0.022 14.9 15.9 4.1 7.7 0.4 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger Spt20 PF12090.8 PVD20824.1 - 0.031 13.9 4.6 0.048 13.3 4.6 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 PVD20824.1 - 0.059 12.5 1.9 0.086 11.9 1.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein zf-LYAR PF08790.11 PVD20824.1 - 0.065 13.1 11.8 11 6.0 0.5 4.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger IBR PF01485.21 PVD20824.1 - 0.12 12.6 18.3 1.3 9.3 1.4 3.9 2 2 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_3rep PF18868.1 PVD20824.1 - 0.14 12.8 0.1 0.14 12.8 0.1 4.6 2 2 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 PVD20824.1 - 0.19 12.0 10.0 5.6 7.3 0.0 5.0 5 0 0 5 5 5 0 zinc-ribbon BolA PF01722.18 PVD20824.1 - 0.19 12.0 2.6 14 6.0 0.3 2.8 2 0 0 2 2 2 0 BolA-like protein zinc_ribbon_15 PF17032.5 PVD20824.1 - 0.35 11.7 17.0 0.18 12.6 0.9 3.2 3 1 1 4 4 3 0 zinc-ribbon family TerY_C PF15616.6 PVD20824.1 - 0.36 10.9 7.4 0.6 10.2 1.6 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain zf-MYND PF01753.18 PVD20824.1 - 0.54 10.4 14.3 3.8 7.7 1.7 3.7 2 1 0 2 2 2 0 MYND finger DUF2256 PF10013.9 PVD20824.1 - 0.62 10.2 11.6 14 5.9 0.0 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Activator_LAG-3 PF11498.8 PVD20824.1 - 2 7.3 15.4 0.051 12.6 8.8 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 LIM PF00412.22 PVD20824.1 - 2.3 8.5 19.5 0.041 14.1 5.0 3.7 2 2 1 3 3 3 0 LIM domain C1_4 PF07975.12 PVD20824.1 - 2.5 8.4 20.4 1.7 8.9 1.8 3.8 3 1 1 4 4 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 PVD20824.1 - 2.7 8.0 24.3 3.1 7.9 0.1 4.2 2 1 2 4 4 4 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 PVD20824.1 - 3.6 7.6 16.6 0.6 10.1 0.1 4.5 5 0 0 5 5 4 0 Nudix N-terminal HNH_5 PF14279.6 PVD20824.1 - 4 7.4 13.4 0.94 9.4 1.0 4.8 5 1 0 5 5 4 0 HNH endonuclease Sprouty PF05210.13 PVD20824.1 - 4.9 7.6 14.6 0.77 10.2 2.4 2.6 2 1 0 2 2 2 0 Sprouty protein (Spry) ADK_lid PF05191.14 PVD20824.1 - 5.1 7.2 13.7 1.1 9.3 0.7 4.0 3 2 0 3 3 3 0 Adenylate kinase, active site lid Elf1 PF05129.13 PVD20824.1 - 7.9 6.6 15.9 3.2 7.9 2.4 3.7 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 PVD20824.1 - 7.9 6.5 18.9 7.4 6.6 0.1 4.9 5 0 0 5 5 5 0 zinc-ribbon domain PIEZO PF15917.5 PVD20826.1 - 0.59 9.6 3.8 0.19 11.2 1.0 1.5 2 0 0 2 2 2 0 Piezo NUDIX_2 PF13869.6 PVD20829.1 - 3e-64 216.1 0.0 3.7e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Kelch_1 PF01344.25 PVD20830.1 - 2.5e-31 107.0 1.8 6.3e-08 32.1 0.0 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 PVD20830.1 - 3.6e-17 62.1 0.5 2.1e-05 24.4 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD20830.1 - 1.3e-13 50.7 2.1 0.09 13.1 0.0 5.7 3 1 2 5 5 5 5 Kelch motif Kelch_3 PF13415.6 PVD20830.1 - 1.1e-12 47.9 1.8 3.2e-06 27.3 0.2 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain BACK PF07707.15 PVD20830.1 - 4.8e-11 42.7 1.2 7.4e-10 38.8 0.2 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 PVD20830.1 - 1.1e-09 37.8 0.5 0.0047 16.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif BTB PF00651.31 PVD20830.1 - 2.8e-07 30.7 0.2 1.3e-06 28.6 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 PVD20830.1 - 0.00027 20.8 8.1 7.4 6.7 0.1 5.4 5 0 0 5 5 5 1 Kelch motif eIF-5_eIF-2B PF01873.17 PVD20831.1 - 5.6e-40 135.9 0.1 9.5e-40 135.1 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SLX9 PF15341.6 PVD20831.1 - 0.056 13.8 3.1 0.1 13.0 3.1 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 SGT1 PF07093.11 PVD20831.1 - 0.6 8.5 4.6 0.9 7.9 4.6 1.2 1 0 0 1 1 1 0 SGT1 protein DUF2151 PF10221.9 PVD20832.1 - 1e-232 774.7 0.0 1.2e-232 774.5 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF1604 PF07713.13 PVD20833.1 - 7.9e-31 105.7 0.1 7.9e-31 105.7 0.1 3.4 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.23 PVD20833.1 - 1.4e-08 34.5 3.7 7.5e-08 32.1 2.9 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PVD20833.1 - 0.00016 21.7 0.2 0.00016 21.7 0.2 2.6 2 0 0 2 2 2 1 G-patch domain SH2 PF00017.24 PVD20834.1 - 2.6e-14 53.1 0.0 6.9e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 PVD20834.1 - 1.5e-08 34.8 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 SOCS box SH2_2 PF14633.6 PVD20834.1 - 0.022 14.2 0.0 0.89 8.9 0.0 2.2 2 0 0 2 2 2 0 SH2 domain Glyco_transf_90 PF05686.12 PVD20835.1 - 1.2e-98 330.6 1.3 1.6e-98 330.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 PVD20835.1 - 8e-12 45.9 0.0 1.7e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 PVD20835.1 - 8.4e-05 22.9 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PAZ PF02170.22 PVD20835.1 - 0.0077 16.0 0.2 0.019 14.7 0.2 1.6 1 0 0 1 1 1 1 PAZ domain BEN PF10523.9 PVD20836.1 - 4.5e-06 26.8 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 BEN domain NifU_N PF01592.16 PVD20836.1 - 0.0072 16.4 0.1 0.016 15.3 0.1 1.6 1 0 0 1 1 1 1 NifU-like N terminal domain UNC-93 PF05978.16 PVD20837.1 - 6.5e-13 48.7 16.4 6.5e-13 48.7 16.4 3.3 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 PVD20837.1 - 2.2e-09 36.7 36.6 4.4e-09 35.7 34.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-LITAF-like PF10601.9 PVD20837.1 - 3.6 7.9 5.0 3.9 7.8 1.0 3.1 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain LRR_8 PF13855.6 PVD20839.1 - 4.8e-76 250.4 123.5 6.1e-13 48.3 2.0 10.3 3 3 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 PVD20839.1 - 3.2e-40 135.4 99.0 1.1e-05 25.7 3.1 14.4 6 5 7 15 15 15 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD20839.1 - 7.9e-23 80.8 8.2 9.6e-05 22.3 0.0 5.4 1 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD20839.1 - 6.1e-16 58.4 36.7 2.7e-05 23.8 1.5 7.2 1 1 8 9 9 9 9 Leucine-rich repeat LRR_1 PF00560.33 PVD20839.1 - 4.1e-09 35.7 64.6 5.8 7.9 0.3 18.0 20 1 0 20 20 20 4 Leucine Rich Repeat LRRNT PF01462.18 PVD20839.1 - 7.3e-07 28.7 5.4 9.1e-07 28.4 2.4 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TIR PF01582.20 PVD20839.1 - 2.1e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.6 PVD20839.1 - 0.00061 19.6 65.3 0.31 11.2 0.5 15.3 16 0 0 16 16 16 4 Leucine Rich repeat TIR_2 PF13676.6 PVD20839.1 - 0.0026 18.3 0.0 0.0079 16.8 0.0 1.9 1 1 0 1 1 1 1 TIR domain TPKR_C2 PF16920.5 PVD20839.1 - 1 9.5 4.1 0.83 9.8 0.6 2.8 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Metallophos PF00149.28 PVD20840.1 - 3.8e-16 60.2 1.5 6.2e-16 59.5 1.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PVD20840.1 - 1.2e-07 32.0 0.0 2.3e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 PVD20840.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Cupin_8 PF13621.6 PVD20841.1 - 5.8e-05 22.9 0.1 8.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain NUDIX PF00293.28 PVD20842.1 - 4e-11 43.1 0.0 6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RHD_DNA_bind PF00554.22 PVD20843.1 - 4.1e-23 82.2 2.0 4.3e-23 82.1 0.1 2.1 2 0 0 2 2 2 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 PVD20843.1 - 4.7e-19 68.3 0.3 1.2e-18 67.0 0.3 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain Cyt-b5 PF00173.28 PVD20844.1 - 1.8e-22 79.3 0.1 2.6e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-H2C2_2 PF13465.6 PVD20845.1 - 3e-31 106.4 134.3 2.7e-05 24.4 0.4 19.3 20 1 0 20 20 20 9 Zinc-finger double domain zf-C2H2 PF00096.26 PVD20845.1 - 4.2e-29 99.3 165.5 0.00054 20.3 0.5 18.6 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20845.1 - 7e-25 85.6 149.6 0.062 14.2 0.1 19.6 19 0 0 19 19 19 14 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD20845.1 - 1.6e-19 69.3 128.4 2.8e-05 23.8 4.3 14.9 16 0 0 16 16 16 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 PVD20845.1 - 3.1e-08 33.7 88.5 0.13 12.6 0.4 15.3 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD20845.1 - 0.00015 21.6 1.3 0.00015 21.6 1.3 13.7 16 0 0 16 16 16 4 C2H2-type zinc finger zf-C2HE PF16278.5 PVD20845.1 - 0.026 15.0 0.0 0.026 15.0 0.0 12.8 9 3 4 13 13 13 0 C2HE / C2H2 / C2HC zinc-binding finger TRAF6_Z2 PF18048.1 PVD20845.1 - 0.36 10.9 32.6 0.33 11.1 0.4 7.7 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 zf-RanBP PF00641.18 PVD20846.1 - 2.4e-07 30.0 1.0 2.4e-07 30.0 1.0 4.1 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others zf-C3HC4 PF00097.25 PVD20846.1 - 1.1e-06 28.4 2.5 1.1e-06 28.4 2.5 4.5 5 1 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD20846.1 - 1.1e-06 28.8 3.4 1.1e-06 28.8 3.4 5.3 5 1 0 5 5 4 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD20846.1 - 1.7e-06 28.0 3.5 1.7e-06 28.0 3.5 3.8 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD20846.1 - 8.1e-06 25.6 2.6 8.1e-06 25.6 2.6 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD20846.1 - 1.4e-05 25.0 2.8 1.4e-05 25.0 2.8 5.4 6 1 1 7 7 4 1 zinc-RING finger domain IBR PF01485.21 PVD20846.1 - 5e-05 23.4 20.2 0.00077 19.6 3.4 4.6 5 0 0 5 5 3 2 IBR domain, a half RING-finger domain ubiquitin PF00240.23 PVD20846.1 - 0.0024 17.6 0.0 0.0068 16.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family RA PF00788.23 PVD20846.1 - 0.0063 17.1 1.2 7.3 7.3 0.0 4.1 3 1 1 4 4 4 1 Ras association (RalGDS/AF-6) domain zf-RING_11 PF17123.5 PVD20846.1 - 0.0082 15.9 4.1 0.0082 15.9 4.1 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PVD20846.1 - 0.017 15.3 4.0 0.017 15.3 4.0 4.2 3 1 0 3 3 2 0 zinc finger of C3HC4-type, RING Maf1 PF09174.10 PVD20847.1 - 6.6e-61 205.5 0.0 8.5e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator MIP PF00230.20 PVD20848.1 - 0.0054 16.5 0.1 0.0061 16.3 0.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Neur_chan_LBD PF02931.23 PVD20849.1 - 2.7e-20 72.7 1.1 4.6e-20 72.0 1.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD20849.1 - 0.082 13.0 15.9 0.25 11.4 8.8 2.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2085 PF09858.9 PVD20849.1 - 1 9.9 8.2 1.8 9.1 6.3 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) LRR_6 PF13516.6 PVD20850.1 - 8.4e-06 25.4 6.9 0.33 11.1 0.1 7.1 8 0 0 8 8 8 1 Leucine Rich repeat CARD_2 PF16739.5 PVD20850.1 - 1.7e-05 24.7 0.1 9.1e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Caspase recruitment domain DUF2153 PF09921.9 PVD20850.1 - 0.0071 16.2 0.6 0.47 10.3 0.1 3.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2153) LRR_8 PF13855.6 PVD20850.1 - 0.022 14.5 21.8 1.3 8.8 0.8 7.5 6 3 2 8 8 8 0 Leucine rich repeat LRR_4 PF12799.7 PVD20850.1 - 0.11 13.0 18.2 17 6.0 0.1 7.1 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) HTH_20 PF12840.7 PVD20850.1 - 0.55 10.3 3.0 6 7.0 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain PEPCK_GTP PF00821.18 PVD20851.1 - 3.6e-128 427.4 0.1 2.2e-66 224.1 0.0 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 PVD20851.1 - 4.9e-95 317.3 0.0 6.6e-95 316.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain HMMR_N PF15905.5 PVD20852.1 - 0.00061 19.4 1.2 0.0013 18.3 1.2 1.5 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TACC_C PF05010.14 PVD20852.1 - 0.0033 17.2 1.2 0.0083 15.9 1.2 1.6 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tup_N PF08581.10 PVD20852.1 - 0.021 15.1 4.2 1.9 8.9 0.4 3.0 2 1 1 3 3 3 0 Tup N-terminal SlyX PF04102.12 PVD20852.1 - 0.063 13.9 13.6 3.6 8.3 1.1 4.2 3 1 1 4 4 4 0 SlyX Planc_extracel PF07595.12 PVD20852.1 - 0.16 11.8 1.6 0.73 9.7 1.6 2.2 1 0 0 1 1 1 0 Planctomycete extracellular DUF1664 PF07889.12 PVD20852.1 - 0.5 10.4 6.1 0.85 9.7 1.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Phasin PF05597.11 PVD20852.1 - 0.53 10.3 4.7 0.25 11.4 0.4 2.6 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nup54 PF13874.6 PVD20852.1 - 3.1 7.9 12.2 0.048 13.8 3.0 2.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Nefa_Nip30_N PF10187.9 PVD20853.1 - 6.5e-11 42.5 11.3 6.5e-11 42.5 11.3 2.2 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DNA_primase_lrg PF04104.14 PVD20853.1 - 0.35 10.2 4.3 0.11 11.9 0.4 1.9 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit UQ_con PF00179.26 PVD20854.1 - 8.5e-41 138.9 0.0 1.6e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 PVD20854.1 - 2.7e-08 33.6 0.1 7.2e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD20854.1 - 6.2e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD20854.1 - 0.0081 16.0 0.3 0.017 15.0 0.3 1.6 1 0 0 1 1 1 1 F-box Ank_2 PF12796.7 PVD20855.1 - 2.7e-29 101.6 4.2 3.6e-09 37.1 0.2 4.7 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20855.1 - 3e-26 91.4 9.7 1.7e-09 38.0 0.2 6.4 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD20855.1 - 4.8e-22 75.7 10.9 1.6e-05 24.9 0.0 7.8 9 1 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 PVD20855.1 - 6.7e-22 76.9 13.3 9.5e-06 25.8 0.0 6.4 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 PVD20855.1 - 9.9e-20 70.4 8.4 1.5e-06 28.4 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD20855.1 - 4.1e-06 27.1 0.3 1e-05 25.8 0.3 1.6 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.25 PVD20856.1 - 1.2e-52 178.9 0.0 1.8e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20856.1 - 5.8e-35 120.8 0.0 7.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD20856.1 - 2.4e-05 23.5 0.0 4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain SSF PF00474.17 PVD20858.1 - 5.6e-43 147.3 28.4 7.8e-43 146.9 28.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Vfa1 PF08432.10 PVD20862.1 - 2.1 8.6 17.0 3.3 8.0 17.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Herpes_US9 PF06072.11 PVD20862.1 - 5.6 6.9 5.2 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Presenilin PF01080.17 PVD20862.1 - 7.3 5.2 11.1 11 4.7 11.1 1.1 1 0 0 1 1 1 0 Presenilin tRNA-synt_1 PF00133.22 PVD20864.1 - 2.5e-130 435.6 0.0 3.8e-129 431.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PVD20864.1 - 9.1e-30 103.6 0.2 1.6e-29 102.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 PVD20864.1 - 7.1e-10 38.7 0.0 5.4e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 PVD20864.1 - 1.6e-07 30.4 1.7 0.0054 15.5 0.2 3.8 3 2 2 5 5 5 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PVD20864.1 - 0.028 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain T-box PF00907.22 PVD20868.1 - 2.8e-77 259.2 0.0 4.2e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 T-box Glycos_transf_2 PF00535.26 PVD20870.1 - 1.4e-19 70.6 0.0 1.7e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PVD20870.1 - 3.5e-05 23.8 0.0 5.6e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PVD20870.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 zf-C2H2 PF00096.26 PVD20871.1 - 2.4e-10 40.3 34.3 9.8e-05 22.6 5.7 4.1 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD20871.1 - 8.3e-09 35.5 26.9 0.0055 17.4 2.8 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD20871.1 - 1.3e-07 31.7 26.9 3.4e-06 27.2 3.2 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD20871.1 - 2.4e-07 30.6 27.4 0.00041 20.3 0.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD20871.1 - 3.9e-05 23.8 14.1 0.0031 17.8 3.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 PVD20871.1 - 0.011 16.4 2.7 0.053 14.3 0.3 2.3 1 1 1 2 2 2 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 PVD20871.1 - 0.05 13.5 8.4 0.071 13.0 4.9 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 PVD20871.1 - 0.078 12.8 17.2 0.14 11.9 3.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 PVD20871.1 - 0.14 12.6 21.4 0.045 14.2 3.8 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD20871.1 - 0.48 10.8 13.7 14 6.1 0.0 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PVD20871.1 - 1.8 8.7 10.6 13 6.0 4.0 3.1 1 1 2 3 3 3 0 Zinc ribbon domain Sprouty PF05210.13 PVD20871.1 - 2 8.9 4.0 8.7 6.8 3.9 1.9 1 1 1 2 2 2 0 Sprouty protein (Spry) Zf_RING PF16744.5 PVD20871.1 - 2.3 8.4 4.5 0.67 10.1 0.1 2.2 2 1 0 2 2 2 0 KIAA1045 RING finger zf-ACC PF17848.1 PVD20871.1 - 3 8.0 4.3 8.5 6.5 0.2 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain XPA_N PF01286.18 PVD20871.1 - 5 7.3 7.7 8.6 6.5 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zinc_ribbon_5 PF13719.6 PVD20871.1 - 7.2 6.5 5.8 3.2 7.6 0.5 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 PVD20871.1 - 8.5 6.5 6.4 64 3.7 6.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 PVD20872.1 - 1.7e-11 44.1 18.6 1e-09 38.4 10.8 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 PVD20872.1 - 0.099 12.9 8.3 0.2 11.9 8.3 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain AIG2_2 PF13772.6 PVD20873.1 - 3.7e-20 72.1 0.0 4.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 PVD20873.1 - 8.1e-06 26.4 0.0 1.3e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like LBP_BPI_CETP_C PF02886.17 PVD20874.1 - 4e-39 134.5 0.0 6.4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 PVD20874.1 - 1.1e-26 93.4 0.0 4.5e-26 91.4 0.0 1.9 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Copine PF07002.16 PVD20875.1 - 2.8e-61 206.8 0.0 5.1e-61 205.9 0.0 1.4 1 1 0 1 1 1 1 Copine C2 PF00168.30 PVD20875.1 - 1.8e-28 98.9 0.0 3.1e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PVD20875.1 - 0.00031 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 PVD20875.1 - 0.0026 18.0 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.32 PVD20876.1 - 8.9e-17 61.2 13.7 0.094 13.6 0.0 7.9 10 1 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD20876.1 - 1.4e-08 34.9 0.1 0.016 15.5 0.0 5.6 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AP_endonuc_2_N PF07582.12 PVD20876.1 - 0.0028 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus Ge1_WD40 PF16529.5 PVD20876.1 - 0.031 13.2 4.4 0.29 10.1 0.1 3.4 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CAP18_C PF12153.8 PVD20876.1 - 0.24 11.3 0.1 0.46 10.4 0.1 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) AA_permease_2 PF13520.6 PVD20877.1 - 1.8e-49 168.7 38.4 1.8e-49 168.7 38.4 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 PVD20877.1 - 7.9e-33 113.8 34.8 1.5e-32 112.9 34.8 1.3 1 0 0 1 1 1 1 Amino acid permease DUF829 PF05705.14 PVD20877.1 - 0.002 18.1 0.1 0.78 9.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Adeno_GP19K PF04881.13 PVD20877.1 - 0.02 14.9 0.2 9.3 6.3 0.0 3.3 3 0 0 3 3 3 0 Adenovirus GP19K Neurensin PF14927.6 PVD20877.1 - 1.1 9.0 5.5 14 5.4 0.0 3.2 3 1 0 3 3 3 0 Neurensin Pkinase PF00069.25 PVD20878.1 - 4.8e-50 170.4 0.3 9.2e-50 169.4 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20878.1 - 2e-22 79.7 0.0 4.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2 PF00096.26 PVD20878.1 - 0.0027 18.1 1.2 0.0027 18.1 1.2 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type Pox_ser-thr_kin PF05445.11 PVD20878.1 - 0.0078 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 PVD20878.1 - 0.6 10.0 3.0 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_15 PF00723.21 PVD20879.1 - 1.5e-107 360.2 0.0 2.2e-107 359.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ank_2 PF12796.7 PVD20879.1 - 2.9e-22 79.1 0.7 1.2e-16 61.1 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD20879.1 - 1.8e-21 76.2 4.1 1.2e-11 44.9 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD20879.1 - 7.3e-18 64.1 3.3 2.3e-05 24.6 0.1 4.6 4 0 0 4 4 3 3 Ankyrin repeat Ank_3 PF13606.6 PVD20879.1 - 1.2e-17 62.2 1.9 4.7e-07 29.6 0.1 4.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PVD20879.1 - 1.9e-15 56.7 4.4 3.7e-06 27.1 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) TPR_12 PF13424.6 PVD20879.1 - 8.2e-14 51.7 6.8 3e-05 24.2 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat LRR_6 PF13516.6 PVD20879.1 - 2.4e-13 49.0 16.4 0.056 13.5 0.0 7.7 7 0 0 7 7 7 5 Leucine Rich repeat TPR_2 PF07719.17 PVD20879.1 - 1.9e-11 43.1 4.3 0.1 12.8 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD20879.1 - 2e-10 40.0 8.2 0.1 12.5 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD20879.1 - 2.3e-07 30.3 8.2 0.21 11.7 0.1 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat LRR_4 PF12799.7 PVD20879.1 - 1.4e-06 28.5 19.6 0.024 15.1 0.4 5.4 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) TPR_8 PF13181.6 PVD20879.1 - 0.00014 21.8 4.9 2 8.8 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD20879.1 - 0.0015 19.2 4.0 1.7 9.6 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD20879.1 - 0.014 15.2 6.5 1.6 8.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TERF2_RBM PF16772.5 PVD20879.1 - 0.14 11.6 0.0 0.63 9.5 0.0 2.1 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif LRR_1 PF00560.33 PVD20879.1 - 0.2 12.3 20.8 10 7.1 0.7 8.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD20879.1 - 0.22 11.3 13.5 4.1 7.2 0.1 5.3 5 0 0 5 5 4 0 Leucine rich repeat TPR_MalT PF17874.1 PVD20879.1 - 0.69 9.2 20.0 0.11 11.9 1.7 3.4 2 1 1 3 3 3 0 MalT-like TPR region VCBS PF13517.6 PVD20880.1 - 9.4e-15 55.0 2.2 0.01 16.4 0.0 4.8 3 1 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PVD20880.1 - 7.9e-05 22.7 8.6 0.22 11.7 0.2 4.5 5 0 0 5 5 5 3 FG-GAP repeat UNC-93 PF05978.16 PVD20882.1 - 2.7e-07 30.4 1.9 2.7e-07 30.4 1.9 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf_UBZ PF18439.1 PVD20883.1 - 0.53 9.9 1.9 0.45 10.2 0.5 1.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger p450 PF00067.22 PVD20886.1 - 4.7e-98 328.9 0.0 6e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb2_2 PF04561.14 PVD20886.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 Chordopox_A13L PF05961.11 PVD20888.1 - 0.03 14.6 0.2 0.047 13.9 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3377 PF11857.8 PVD20888.1 - 0.042 13.8 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Spo7 PF03907.13 PVD20888.1 - 0.064 12.7 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Spo7-like protein Flu_M2 PF00599.17 PVD20888.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Adeno_E3_CR2 PF02439.15 PVD20888.1 - 0.12 12.1 8.1 0.083 12.7 6.9 1.4 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Orf78 PF06024.12 PVD20888.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Cyt-b5 PF00173.28 PVD20889.1 - 9.9e-23 80.1 0.0 1.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tsg PF04668.12 PVD20890.1 - 2.8e-45 154.3 1.6 3.7e-45 153.9 1.6 1.2 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region PseudoU_synth_2 PF00849.22 PVD20891.1 - 3.4e-27 95.5 0.3 2.4e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase Integrin_b_cyt PF08725.11 PVD20891.1 - 0.057 13.1 0.2 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain TGS PF02824.21 PVD20891.1 - 0.076 13.1 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 TGS domain Topoisom_I PF01028.20 PVD20892.1 - 8.8e-100 332.7 7.9 8.8e-100 332.7 7.9 2.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 PVD20892.1 - 2e-70 236.6 8.2 6.4e-65 218.6 4.1 4.7 4 1 1 5 5 5 2 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 PVD20892.1 - 2.7e-33 113.7 1.4 9.5e-33 112.0 1.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain FACT-Spt16_Nlob PF14826.6 PVD20893.1 - 2.2e-44 151.1 7.5 4.1e-44 150.2 0.7 3.4 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 PVD20893.1 - 4.1e-28 98.5 0.1 4.1e-28 98.5 0.1 2.9 3 1 1 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 PVD20893.1 - 7e-25 87.9 0.0 1.5e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 PVD20893.1 - 5e-18 65.3 0.1 1.4e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Pkinase PF00069.25 PVD20894.1 - 9.2e-73 244.8 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20894.1 - 1.2e-41 142.8 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD20894.1 - 2.1e-05 24.0 0.0 0.00013 21.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Mg-por_mtran_C PF07109.11 PVD20894.1 - 0.018 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus FTA2 PF13095.6 PVD20894.1 - 0.039 13.6 0.2 4 7.0 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PVD20894.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tubulin PF00091.25 PVD20895.1 - 4.5e-68 229.3 0.0 6e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 PVD20895.1 - 2.4e-05 24.6 0.0 5.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_C PF03953.17 PVD20895.1 - 0.0002 21.5 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PVD20895.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PVD20895.1 - 0.033 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like HOIP-UBA PF16678.5 PVD20896.1 - 4.4e-38 130.7 1.7 7.5e-37 126.7 1.0 2.7 2 0 0 2 2 2 1 HOIP UBA domain pair E3_UbLigase_RBR PF18091.1 PVD20896.1 - 1.6e-26 92.2 0.1 1.6e-26 92.2 0.1 3.1 2 0 0 2 2 2 1 E3 Ubiquitin Ligase RBR C-terminal domain Robl_LC7 PF03259.17 PVD20896.1 - 1.1e-22 79.6 0.0 2.8e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Roadblock/LC7 domain IBR PF01485.21 PVD20896.1 - 1.1e-08 35.2 27.6 2.6e-08 34.0 9.0 5.0 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain PUB PF09409.10 PVD20896.1 - 1.2e-07 31.6 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 PUB domain zf-RanBP PF00641.18 PVD20896.1 - 0.00046 19.4 2.0 0.00046 19.4 2.0 5.5 6 1 0 6 6 6 1 Zn-finger in Ran binding protein and others zf-B_box PF00643.24 PVD20896.1 - 0.0031 17.6 6.1 0.0031 17.6 6.1 6.1 5 0 0 5 5 5 1 B-box zinc finger UBA PF00627.31 PVD20896.1 - 0.065 13.2 7.2 0.32 11.0 0.0 3.5 4 0 0 4 4 4 0 UBA/TS-N domain DUF1704 PF08014.11 PVD20897.1 - 1.6e-14 53.8 0.0 3.6e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) GST_N_3 PF13417.6 PVD20898.1 - 4.8e-15 55.7 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD20898.1 - 2e-10 40.8 0.0 4.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD20898.1 - 1.1e-07 31.8 0.1 2.1e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD20898.1 - 1e-06 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD20898.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD20898.1 - 0.0093 16.2 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RIO1 PF01163.22 PVD20899.1 - 2.9e-08 33.5 0.1 4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PVD20899.1 - 4.4e-07 29.5 0.2 5.7e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PVD20899.1 - 4e-06 26.3 0.4 7.4e-06 25.5 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PVD20899.1 - 1.6e-05 24.3 0.5 2e-05 24.0 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1679 PF07914.11 PVD20899.1 - 0.011 14.6 0.1 0.023 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 PVD20899.1 - 0.048 13.2 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sas10_Utp3 PF04000.15 PVD20900.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.6 2 1 0 2 2 2 0 Sas10/Utp3/C1D family DUF1077 PF06417.12 PVD20901.1 - 3.9e-45 152.7 3.3 4.7e-45 152.4 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) C2-C2_1 PF11618.8 PVD20902.1 - 6e-65 217.6 0.0 4.4e-55 185.6 0.0 2.8 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 PVD20902.1 - 2.1e-53 180.6 0.0 2.1e-53 180.6 0.0 3.2 4 0 0 4 4 4 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 PVD20902.1 - 3.5e-10 40.1 0.0 1.6e-09 37.9 0.0 2.3 1 0 0 1 1 1 1 C2 domain DUF4200 PF13863.6 PVD20902.1 - 0.013 15.9 8.5 0.013 15.9 8.5 6.3 4 1 1 6 6 6 0 Domain of unknown function (DUF4200) Homeobox_KN PF05920.11 PVD20904.1 - 2.8e-16 59.1 0.8 5.2e-16 58.3 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD20904.1 - 5.3e-07 29.4 0.4 8.8e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD20907.1 - 2.4e-16 59.4 0.9 4.8e-16 58.4 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD20907.1 - 4.9e-07 29.5 0.1 1.1e-06 28.3 0.1 1.6 2 0 0 2 2 2 1 Homeodomain PI-PLC-X PF00388.19 PVD20908.1 - 7.4e-61 204.0 0.0 1.8e-60 202.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PVD20908.1 - 6.3e-33 113.5 0.0 1.4e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 PVD20908.1 - 1.3e-11 44.7 0.0 2.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain SH2 PF00017.24 PVD20908.1 - 1.7e-06 28.0 0.1 0.35 11.0 0.1 3.9 2 1 1 3 3 3 2 SH2 domain EF-hand_like PF09279.11 PVD20908.1 - 0.0027 18.1 0.1 0.0089 16.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH PF00169.29 PVD20908.1 - 0.015 15.8 0.0 15 6.2 0.0 3.1 3 0 0 3 3 3 0 PH domain CR6_interact PF10147.9 PVD20908.1 - 0.097 12.4 0.3 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CS PF04969.16 PVD20909.1 - 2.4e-11 44.5 0.0 6.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 CS domain TSC22 PF01166.18 PVD20910.1 - 0.00011 22.4 2.1 0.018 15.3 0.1 3.0 2 1 0 2 2 2 1 TSC-22/dip/bun family HAP1_N PF04849.13 PVD20910.1 - 0.00017 20.9 9.3 0.00028 20.2 9.3 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4686 PF15742.5 PVD20910.1 - 0.0022 17.2 14.7 0.0033 16.6 14.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Golgin_A5 PF09787.9 PVD20910.1 - 0.0048 16.4 13.7 0.01 15.4 13.7 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 YPEB PF14620.6 PVD20910.1 - 0.01 15.2 6.7 0.019 14.3 6.7 1.4 1 0 0 1 1 1 0 YpeB sporulation bZIP_1 PF00170.21 PVD20910.1 - 0.014 15.5 10.5 0.043 13.9 0.2 3.9 2 1 3 5 5 5 0 bZIP transcription factor YabA PF06156.13 PVD20910.1 - 0.025 15.2 1.4 0.025 15.2 1.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA GIT_CC PF16559.5 PVD20910.1 - 0.027 14.3 2.6 0.027 14.3 2.6 3.7 3 1 1 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 PVD20910.1 - 0.03 14.4 7.9 0.065 13.3 7.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 PVD20910.1 - 0.043 12.7 20.1 0.0096 14.8 15.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Herpes_UL25 PF01499.16 PVD20910.1 - 0.058 11.9 9.3 0.09 11.3 9.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3972 PF13118.6 PVD20910.1 - 0.11 13.0 0.5 0.11 13.0 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3972) TetR_C_24 PF17932.1 PVD20910.1 - 0.13 12.6 6.3 0.23 11.7 6.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Laminin_I PF06008.14 PVD20910.1 - 0.13 12.0 17.1 0.35 10.5 17.0 1.6 1 1 0 1 1 1 0 Laminin Domain I Fib_alpha PF08702.10 PVD20910.1 - 0.16 12.2 8.8 0.39 10.9 8.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Viral_P18 PF04521.13 PVD20910.1 - 0.22 11.3 1.8 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Leu_zip PF15294.6 PVD20910.1 - 0.26 10.8 16.1 0.69 9.4 16.1 1.6 1 1 0 1 1 1 0 Leucine zipper HALZ PF02183.18 PVD20910.1 - 0.28 11.4 8.1 1.2 9.4 0.1 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4634 PF15465.6 PVD20910.1 - 0.31 11.3 1.0 0.74 10.1 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) DUF4618 PF15397.6 PVD20910.1 - 0.36 10.2 14.5 0.3 10.5 8.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Vps53_N PF04100.12 PVD20910.1 - 0.42 9.5 10.7 1.3 7.9 10.7 1.7 1 1 0 1 1 1 0 Vps53-like, N-terminal DUF4763 PF15960.5 PVD20910.1 - 0.48 9.7 11.7 0.15 11.3 3.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) ADIP PF11559.8 PVD20910.1 - 0.59 10.2 19.8 4.5 7.4 10.9 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Hemerythrin PF01814.23 PVD20910.1 - 0.65 10.6 5.0 1.2 9.8 5.0 1.5 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4795 PF16043.5 PVD20910.1 - 0.83 9.2 15.5 2 8.0 15.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Ax_dynein_light PF10211.9 PVD20910.1 - 0.95 9.4 17.7 3.5 7.5 8.1 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3037 PF11236.8 PVD20910.1 - 1.1 9.7 6.6 2 8.8 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) KASH_CCD PF14662.6 PVD20910.1 - 1.2 8.9 20.5 3.6 7.4 20.5 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 PVD20910.1 - 1.4 8.5 21.2 0.75 9.4 1.4 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bMG3 PF11974.8 PVD20910.1 - 1.8 8.6 5.9 1.2 9.2 2.9 2.2 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain Swi5 PF07061.11 PVD20910.1 - 2.1 8.5 9.2 17 5.6 0.8 3.0 1 1 1 2 2 2 0 Swi5 DUF2594 PF10769.9 PVD20910.1 - 2.7 8.1 6.8 1.4 9.0 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2594) MnmE_helical PF12631.7 PVD20910.1 - 3.4 7.8 10.8 4.2 7.5 7.2 2.1 1 1 1 2 2 2 0 MnmE helical domain DUF5082 PF16888.5 PVD20910.1 - 3.7 7.8 11.9 1.8 8.9 1.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Hormone_1 PF00103.20 PVD20910.1 - 3.8 7.2 8.2 28 4.4 0.5 3.1 1 1 1 2 2 2 0 Somatotropin hormone family TMF_DNA_bd PF12329.8 PVD20910.1 - 4.1 7.5 19.4 1.1 9.4 1.3 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 PVD20910.1 - 4.1 7.4 9.7 4.5 7.3 6.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PVD20910.1 - 5.6 7.5 7.1 3.7 8.1 0.7 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 PVD20910.1 - 6 7.0 14.8 3.1 7.9 12.2 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 PVD20910.1 - 6 6.1 21.6 5.2 6.3 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CLZ PF16526.5 PVD20910.1 - 7 7.1 16.2 0.58 10.5 2.1 2.9 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 PVD20910.1 - 7.5 5.8 17.5 18 4.6 17.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 PVD20910.1 - 7.9 7.0 23.4 1.1 9.8 4.3 3.2 1 1 1 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 PVD20910.1 - 9.8 6.4 21.2 47 4.2 4.4 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 dNK PF01712.19 PVD20911.1 - 3.6e-30 105.4 0.5 4e-30 105.2 0.5 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 PVD20911.1 - 0.02 15.5 0.1 0.031 14.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PVD20911.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PVD20911.1 - 0.067 13.6 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-TRAF PF02176.18 PVD20912.1 - 2.5e-07 31.3 1.1 2.5e-07 31.3 1.1 3.1 2 1 1 3 3 3 1 TRAF-type zinc finger Sina PF03145.16 PVD20912.1 - 7.2e-07 29.3 0.4 7.2e-07 29.3 0.4 1.8 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 PVD20912.1 - 0.00011 22.0 15.8 0.00011 22.0 15.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 PVD20912.1 - 0.69 10.4 8.0 1.8 9.0 8.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Piezo_RRas_bdg PF12166.8 PVD20913.1 - 4.7e-122 408.3 0.5 1.1e-121 407.1 0.5 1.7 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 PVD20913.1 - 1.2e-39 136.2 5.0 6.7e-37 127.2 1.2 3.0 1 1 1 2 2 2 2 Piezo Snf7 PF03357.21 PVD20914.1 - 8.6e-11 41.7 18.8 8.6e-11 41.7 18.8 1.8 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 PVD20914.1 - 9.5e-05 22.4 8.3 0.00014 21.9 8.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 PVD20914.1 - 0.0059 16.3 1.0 0.0094 15.6 0.1 1.7 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase CAS_CSE1 PF03378.15 PVD20914.1 - 0.0081 14.7 1.1 0.0092 14.5 1.1 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus UPF0176_N PF17773.1 PVD20914.1 - 0.075 13.4 2.0 0.73 10.2 0.0 2.5 1 1 0 2 2 2 0 UPF0176 acylphosphatase like domain DUF1779 PF08680.10 PVD20914.1 - 0.27 11.4 9.3 0.44 10.7 9.3 1.4 1 1 0 1 1 1 0 TATA-box binding DUF1843 PF08898.10 PVD20914.1 - 0.34 11.4 0.1 0.34 11.4 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Neur_chan_LBD PF02931.23 PVD20915.1 - 2.6e-26 92.4 0.6 3.7e-26 91.9 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 PVD20916.1 - 1.5e-82 276.2 16.7 6.6e-28 97.6 4.1 3.4 3 0 0 3 3 3 3 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD20916.1 - 1.1e-21 78.1 11.2 7.4e-11 42.6 0.0 3.8 4 0 0 4 4 4 3 Neurotransmitter-gated ion-channel transmembrane region DUF4793 PF16041.5 PVD20916.1 - 0.053 13.7 5.2 1.8 8.7 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) HEAT PF02985.22 PVD20917.1 - 0.0029 17.7 3.6 8.5 6.9 0.1 4.7 5 0 0 5 5 5 1 HEAT repeat EF-G-binding_N PF07299.11 PVD20917.1 - 0.027 15.0 1.4 1.9 9.0 0.2 3.5 3 1 0 3 3 3 0 Elongation factor G-binding protein, N-terminal Vfa1 PF08432.10 PVD20917.1 - 0.12 12.7 1.0 0.22 11.9 1.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DAO_C PF16901.5 PVD20917.1 - 0.12 12.2 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase Sigma70_ner PF04546.13 PVD20917.1 - 0.81 9.5 4.8 0.13 12.1 0.7 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Pkinase PF00069.25 PVD20918.1 - 1.6e-68 230.9 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD20918.1 - 3e-33 115.2 0.0 4.2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD20918.1 - 5e-05 22.4 0.1 0.00039 19.5 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD20918.1 - 0.004 16.5 0.0 0.024 14.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 PVD20918.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PVD20918.1 - 0.021 13.6 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PVD20918.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TMEM189_B_dmain PF10520.9 PVD20919.1 - 9.5e-78 260.3 6.6 9.5e-78 260.3 6.6 1.5 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain 7TMR-DISM_7TM PF07695.11 PVD20919.1 - 0.051 13.5 1.8 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling GTP1_OBG PF01018.22 PVD20920.1 - 6.6e-51 172.0 6.2 8.4e-51 171.6 6.2 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 PVD20920.1 - 8.5e-24 83.8 0.0 1.3e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD20920.1 - 4.8e-09 35.9 0.0 7.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 PVD20920.1 - 0.0026 17.3 0.0 0.0063 16.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 PVD20920.1 - 0.075 12.0 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 PVD20920.1 - 0.077 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter IRF PF00605.17 PVD20921.1 - 3e-32 111.0 0.3 6.1e-32 110.0 0.3 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 PVD20921.1 - 1.4e-13 51.1 0.1 1.9e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Interferon-regulatory factor 3 LRR_6 PF13516.6 PVD20922.1 - 1.5e-11 43.3 9.7 0.00075 19.4 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat Caskin-Pro-rich PF16907.5 PVD20922.1 - 0.025 15.1 0.6 0.051 14.1 0.6 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins LRR_1 PF00560.33 PVD20922.1 - 0.17 12.5 4.7 47 5.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat IRF PF00605.17 PVD20923.1 - 6.2e-39 132.5 0.0 1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 PVD20923.1 - 1.3e-21 77.2 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Metallophos PF00149.28 PVD20925.1 - 2e-16 61.1 0.2 3e-16 60.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PVD20925.1 - 1.4e-09 38.6 0.0 3.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PVD20925.1 - 0.087 13.0 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DNA_ligase_OB_2 PF14743.6 PVD20926.1 - 4.3e-26 90.7 0.5 2.7e-25 88.2 0.2 2.3 2 0 0 2 2 2 1 DNA ligase OB-like domain zf-CCHH PF10283.9 PVD20926.1 - 1.9e-20 72.5 13.1 1e-10 41.4 5.1 2.6 2 0 0 2 2 2 2 PBZ domain DNA_ligase_A_M PF01068.21 PVD20926.1 - 2.5e-12 46.9 3.8 2.6e-12 46.8 0.4 2.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 PVD20926.1 - 0.00014 22.2 0.3 0.0013 19.1 0.3 2.3 1 1 0 1 1 1 1 RNA ligase VWA PF00092.28 PVD20927.1 - 2.7e-54 184.1 2.0 4e-35 121.6 0.0 3.2 2 1 1 3 3 3 3 von Willebrand factor type A domain VWC PF00093.18 PVD20927.1 - 2.9e-14 53.1 438.3 0.023 15.0 14.8 21.8 23 0 0 23 23 23 19 von Willebrand factor type C domain VWA_2 PF13519.6 PVD20927.1 - 3.9e-13 50.0 0.0 3.7e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD20927.1 - 2.6e-06 27.5 0.0 0.082 12.8 0.0 2.9 2 1 1 3 3 3 2 von Willebrand factor type A domain ShK PF01549.24 PVD20927.1 - 3.5e-06 27.5 26.8 0.00013 22.4 8.6 7.1 5 0 0 5 5 5 2 ShK domain-like Copine PF07002.16 PVD20927.1 - 0.013 14.9 0.1 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Copine ShK PF01549.24 PVD20928.1 - 1.5e-11 44.7 68.6 5.1e-05 23.7 8.9 7.4 6 1 0 6 6 6 5 ShK domain-like HofP PF10748.9 PVD20928.1 - 0.021 14.4 0.1 0.11 12.0 0.0 2.2 3 0 0 3 3 3 0 DNA utilization proteins HofP Keratin_2_head PF16208.5 PVD20934.1 - 0.36 10.9 22.4 0.43 10.7 22.4 1.1 1 0 0 1 1 1 0 Keratin type II head Metal_resist PF13801.6 PVD20941.1 - 3.7 7.7 8.3 0.32 11.2 2.3 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Homeobox_KN PF05920.11 PVD20945.1 - 7.7e-16 57.7 0.2 1.7e-15 56.6 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD20945.1 - 3.5e-07 30.0 1.3 6e-07 29.2 1.3 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 PVD20945.1 - 0.092 13.3 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Rhabdo_ncap PF00945.18 PVD20945.1 - 0.68 8.8 1.9 1 8.2 1.9 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CAP_N PF01213.19 PVD20946.1 - 0.01 15.4 4.3 0.016 14.7 4.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PVD20946.1 - 0.8 9.8 8.9 1.8 8.6 8.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Homeobox_KN PF05920.11 PVD20947.1 - 0.00022 21.1 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD20947.1 - 0.0049 16.7 0.4 0.0086 15.9 0.4 1.5 1 0 0 1 1 1 1 Homeodomain VIR_N PF15912.5 PVD20947.1 - 2.1 7.9 8.0 2.8 7.5 8.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal MYT1 PF08474.11 PVD20955.1 - 6.9 6.5 9.5 11 5.9 9.5 1.2 1 0 0 1 1 1 0 Myelin transcription factor 1 Homeobox_KN PF05920.11 PVD20957.1 - 1.8e-16 59.8 0.3 2.9e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD20957.1 - 1.1e-07 31.6 2.5 1.6e-07 31.0 2.5 1.3 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 PVD20957.1 - 0.06 13.9 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 C1q PF00386.21 PVD20959.1 - 8.3e-27 93.9 0.2 1.3e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 PVD20960.1 - 1.9e-23 83.0 0.0 2.8e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 C1q domain PA14 PF07691.12 PVD20960.1 - 0.015 15.1 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 PA14 domain Syntaxin-6_N PF09177.11 PVD20960.1 - 0.044 14.4 0.0 0.083 13.5 0.0 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DDE_Tnp_4 PF13359.6 PVD20961.1 - 3e-08 33.5 0.0 3.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PVD20961.1 - 0.0025 17.5 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Not1 PF04054.15 PVD20962.1 - 6e-153 509.1 4.0 1.6e-152 507.7 4.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 PVD20962.1 - 1.5e-79 266.5 3.9 1.6e-79 266.4 1.3 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PVD20962.1 - 1.3e-47 161.4 7.0 1.3e-47 161.4 7.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) Xpo1 PF08389.12 PVD20962.1 - 0.18 11.9 1.9 57 3.7 0.1 4.3 3 1 1 4 4 4 0 Exportin 1-like protein TetR_C_15 PF17918.1 PVD20962.1 - 1.3 9.8 3.9 4.4 8.1 0.4 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3361 PF11841.8 PVD20964.1 - 3.1e-50 170.1 2.0 8e-50 168.8 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 PVD20964.1 - 9.5e-35 120.3 0.1 1.8e-34 119.4 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 PVD20964.1 - 9.1e-14 52.1 0.0 2.1e-10 41.2 0.0 3.0 1 1 1 2 2 2 2 Pleckstrin homology domain Ras PF00071.22 PVD20965.1 - 4.8e-21 75.0 0.0 8.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 PVD20965.1 - 6.6e-05 22.9 0.1 0.031 14.2 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 PVD20965.1 - 0.00024 21.3 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PVD20965.1 - 0.00074 19.9 0.2 0.0035 17.7 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 PVD20965.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 PVD20965.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 PVD20965.1 - 0.047 14.0 0.0 0.54 10.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PVD20965.1 - 0.047 13.4 0.1 0.22 11.2 0.0 2.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 PVD20965.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 PVD20965.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 PVD20967.1 - 7.5e-23 80.9 0.2 1.4e-22 80.0 0.2 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD20967.1 - 1.2e-05 25.5 0.2 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 PVD20967.1 - 0.00039 20.2 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 PVD20967.1 - 0.00071 19.5 0.9 0.35 10.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 PVD20967.1 - 0.0048 16.4 0.5 0.71 9.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_7 PF12775.7 PVD20967.1 - 0.016 14.8 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 PVD20967.1 - 0.019 14.5 0.2 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PVD20967.1 - 0.022 15.2 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PVD20967.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) E1_DerP2_DerF2 PF02221.15 PVD20969.1 - 0.00011 22.7 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 ML domain YukC PF10140.9 PVD20969.1 - 0.19 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CUB PF00431.20 PVD20970.1 - 5.6e-27 94.3 0.5 8.4e-07 29.3 0.0 4.5 4 1 0 4 4 4 4 CUB domain Cadherin PF00028.17 PVD20974.1 - 1.7e-31 108.5 1.4 4.1e-12 46.4 0.1 4.6 4 1 1 5 5 5 4 Cadherin domain Cadherin_2 PF08266.12 PVD20974.1 - 1.9e-12 46.8 0.1 3.7e-10 39.5 0.0 3.6 4 0 0 4 4 4 1 Cadherin-like Cadherin PF00028.17 PVD20975.1 - 8.2e-41 138.4 1.9 6.5e-20 71.4 0.4 3.5 3 0 0 3 3 3 3 Cadherin domain DUF4585 PF15232.6 PVD20975.1 - 0.03 14.4 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) ORC6 PF05460.13 PVD20975.1 - 1 8.5 4.7 3.1 7.0 4.9 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF19 PF01579.18 PVD20976.1 - 0.013 15.3 0.8 0.068 13.0 0.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF19 PF01579.18 PVD20977.1 - 0.00021 21.1 0.8 0.00057 19.7 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF19) CPG4 PF15481.6 PVD20977.1 - 0.00031 21.3 6.3 0.039 14.6 0.3 2.5 1 1 1 2 2 2 2 Chondroitin proteoglycan 4 7tm_1 PF00001.21 PVD20978.1 - 7.6e-24 84.4 9.6 9.8e-24 84.1 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD20978.1 - 4.7e-11 42.5 19.1 1.3e-07 31.2 9.4 3.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD20978.1 - 1.1e-05 24.9 8.3 1.1e-05 24.9 8.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx AvrL567-A PF11529.8 PVD20978.1 - 0.028 14.6 0.3 0.072 13.3 0.1 1.7 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A HA2 PF04408.23 PVD20980.1 - 2.7e-21 75.9 0.0 2.7e-21 75.9 0.0 4.5 4 2 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD20980.1 - 4.7e-17 62.1 0.0 1.1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD20980.1 - 2.1e-08 34.5 0.0 5.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD20980.1 - 7.3e-06 25.9 0.1 1.7e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD20980.1 - 1.8e-05 25.1 0.0 5.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD20980.1 - 0.0012 19.2 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD20980.1 - 0.0016 17.6 0.0 0.0044 16.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 PVD20980.1 - 0.0017 18.4 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 PVD20980.1 - 0.0044 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 PVD20980.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PVD20980.1 - 0.065 13.7 0.5 0.065 13.7 0.5 4.3 3 2 0 3 3 2 0 AAA domain AAA_7 PF12775.7 PVD20980.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 PVD20980.1 - 0.079 13.0 0.6 1.1 9.3 0.2 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD20980.1 - 0.081 12.8 1.4 0.11 12.4 0.1 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea DUF3663 PF12404.8 PVD20980.1 - 0.097 12.7 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 Peptidase ATPase PF06745.13 PVD20980.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.7 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 PVD20980.1 - 0.18 11.8 3.7 5.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 PVD20980.1 - 0.51 10.9 0.0 0.51 10.9 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 PVD20980.1 - 0.52 10.5 0.0 0.52 10.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain p450 PF00067.22 PVD20981.1 - 8.8e-71 239.0 0.0 1.4e-70 238.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CD225 PF04505.12 PVD20981.1 - 0.00058 19.9 6.2 0.0016 18.5 6.2 1.7 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Peptidase_M54 PF07998.11 PVD20982.1 - 0.044 13.8 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Transglut_N PF00868.20 PVD20983.1 - 6e-23 81.4 0.1 1.5e-21 76.9 0.0 2.9 3 0 0 3 3 3 1 Transglutaminase family Transglut_core PF01841.19 PVD20983.1 - 8.4e-16 58.4 0.2 2.4e-15 57.0 0.2 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 PVD20983.1 - 0.01 15.9 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain DUF11 PF01345.18 PVD20983.1 - 0.053 13.8 2.5 0.32 11.3 0.3 3.2 2 1 0 2 2 2 0 Domain of unknown function DUF11 Acetyltransf_9 PF13527.7 PVD20983.1 - 0.15 12.1 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Transglut_core PF01841.19 PVD20984.1 - 3.6e-10 40.3 0.1 1.1e-09 38.8 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 PVD20984.1 - 0.0034 17.5 0.1 5.7 7.1 0.0 2.9 3 1 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain DUF11 PF01345.18 PVD20984.1 - 0.058 13.7 1.2 0.65 10.3 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF11 Fn3-like PF14310.6 PVD20984.1 - 0.13 12.4 0.9 3.5 7.8 0.1 3.0 2 1 1 3 3 3 0 Fibronectin type III-like domain Transglut_core PF01841.19 PVD20985.1 - 7.4e-16 58.6 0.4 1.4e-15 57.7 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 PVD20985.1 - 1.5e-10 41.4 0.0 1.7e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 PVD20985.1 - 0.0018 18.4 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 PVD20986.1 - 4.1e-18 65.8 0.1 6.2e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 PVD20987.1 - 6.6e-10 39.4 0.1 2e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 PVD20987.1 - 0.00031 20.8 0.0 0.024 14.8 0.0 2.6 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Aurora-A_bind PF09041.10 PVD20987.1 - 0.12 12.5 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Aurora-A binding Ras PF00071.22 PVD20989.1 - 2e-24 86.0 0.0 3.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD20989.1 - 5.3e-05 23.4 0.0 0.00022 21.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD20989.1 - 0.0011 18.9 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 PVD20989.1 - 0.0029 17.1 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 PVD20989.1 - 0.01 16.4 0.1 0.042 14.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD20989.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 PVD20989.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 PVD20989.1 - 0.015 15.6 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain CENP-M PF11111.8 PVD20989.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) NACHT PF05729.12 PVD20989.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 PVD20989.1 - 0.03 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 PVD20989.1 - 0.031 14.5 0.1 0.27 11.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain VirE PF05272.11 PVD20989.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E AAA_24 PF13479.6 PVD20989.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain hEGF PF12661.7 PVD20990.1 - 2.1 9.1 5.3 0.47 11.2 1.3 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF dCache_1 PF02743.18 PVD20992.1 - 1.4e-06 28.3 0.8 0.046 13.5 0.1 2.3 2 0 0 2 2 2 2 Cache domain EGF_3 PF12947.7 PVD20992.1 - 0.11 12.7 7.5 1.8 8.8 0.6 2.7 2 0 0 2 2 2 0 EGF domain FXa_inhibition PF14670.6 PVD20992.1 - 1.4 9.2 10.5 3.6 8.0 1.2 2.7 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD20992.1 - 1.7 8.7 6.7 1.8 8.6 0.5 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 PVD20992.1 - 3 8.6 14.1 0.75 10.5 1.3 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.15 PVD20992.1 - 3.6 7.9 12.4 1 9.6 1.7 3.1 2 1 0 2 2 2 0 Calcium-binding EGF domain EGF PF00008.27 PVD20992.1 - 4 7.8 15.9 2.3 8.6 2.7 2.9 3 0 0 3 3 3 0 EGF-like domain DUF1117 PF06547.12 PVD20992.1 - 7.2 7.2 6.3 12 6.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) GCIP PF13324.6 PVD20993.1 - 2.1e-54 184.9 2.7 3.1e-54 184.3 2.7 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting YopD PF05844.12 PVD20993.1 - 0.031 13.3 0.3 0.049 12.7 0.3 1.2 1 0 0 1 1 1 0 YopD protein MRP-63 PF14978.6 PVD20993.1 - 0.12 13.0 0.0 0.36 11.5 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 PhaP_Bmeg PF09602.10 PVD20993.1 - 0.25 11.3 3.4 2.2 8.2 0.3 3.3 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) dsDNA_bind PF01984.20 PVD20994.1 - 3.2e-19 69.2 0.6 3.6e-19 69.1 0.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain STD1 PF17235.2 PVD20994.1 - 0.041 13.5 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 STD1/MTH1 DUF1773 PF08593.10 PVD20995.1 - 0.0086 17.1 0.2 1.9 9.6 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function CD225 PF04505.12 PVD20997.1 - 7.9e-12 45.1 4.0 1.1e-11 44.7 4.0 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DsbD_2 PF13386.6 PVD20997.1 - 0.0008 19.4 0.9 0.001 19.0 0.9 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF4199 PF13858.6 PVD20997.1 - 0.036 14.4 0.3 0.054 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2723 PF11028.8 PVD20997.1 - 0.06 13.3 2.7 0.29 11.0 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2723) DUF2754 PF10953.8 PVD20997.1 - 0.096 12.9 3.9 0.96 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF2838 PF10998.8 PVD20997.1 - 0.21 11.8 3.1 0.67 10.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2838) DUF4190 PF13828.6 PVD20997.1 - 3.1 7.6 8.3 13 5.6 7.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) HSF_DNA-bind PF00447.17 PVD20998.1 - 2.2e-31 108.3 0.8 4.8e-31 107.2 0.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.11 PVD20998.1 - 0.00018 21.3 13.7 0.00018 21.3 13.7 2.4 3 0 0 3 3 3 1 Vertebrate heat shock transcription factor HALZ PF02183.18 PVD20998.1 - 0.026 14.7 0.5 0.026 14.7 0.5 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 PVD20998.1 - 0.15 12.2 2.3 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 PVD20998.1 - 0.75 10.3 4.2 0.68 10.4 2.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Peptidase_M24 PF00557.24 PVD20999.1 - 2.1e-27 96.2 0.0 6.3e-27 94.6 0.0 1.9 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PVD20999.1 - 3.4e-27 94.6 0.0 6.1e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 PVD20999.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF2895 PF11444.8 PVD21000.1 - 0.023 14.1 1.3 0.041 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Peptidase_S10 PF00450.22 PVD21000.1 - 0.12 11.8 2.5 0.64 9.4 0.1 2.3 1 1 1 2 2 2 0 Serine carboxypeptidase Lzipper-MIP1 PF14389.6 PVD21000.1 - 1 9.7 11.6 6.1 7.2 0.2 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 EF-hand_1 PF00036.32 PVD21001.1 - 9e-30 100.0 7.4 2.3e-07 29.9 0.1 5.8 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 PVD21001.1 - 9.6e-30 100.0 1.5 1e-06 28.2 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 PVD21001.1 - 6.9e-29 100.1 1.6 8.4e-11 42.2 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PVD21001.1 - 3e-23 81.4 1.9 4.2e-10 39.3 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD21001.1 - 5.3e-21 73.1 1.2 7.3e-06 25.2 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 PVD21001.1 - 0.00092 19.5 0.0 3.9 7.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain XS PF03468.14 PVD21001.1 - 0.012 15.9 0.1 1.9 8.8 0.0 2.1 1 1 1 2 2 2 0 XS domain GUN4 PF05419.12 PVD21001.1 - 0.026 14.6 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 GUN4-like EF-hand_10 PF14788.6 PVD21001.1 - 0.07 13.0 0.3 18 5.3 0.0 3.3 3 1 1 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.9 PVD21001.1 - 0.1 12.9 0.5 5.2 7.4 0.1 2.8 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA PF00004.29 PVD21002.1 - 1.7e-28 99.7 0.0 2.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD21002.1 - 2.2e-07 31.2 0.0 6.7e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD21002.1 - 2.4e-05 24.9 0.0 7e-05 23.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PVD21002.1 - 5.5e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 PVD21002.1 - 0.0011 19.3 0.0 0.0053 17.1 0.0 2.1 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 PVD21002.1 - 0.0012 18.9 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 PVD21002.1 - 0.0016 18.1 0.0 0.053 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PVD21002.1 - 0.0018 18.0 0.1 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 PVD21002.1 - 0.0027 18.0 0.0 0.016 15.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PVD21002.1 - 0.0036 17.5 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PVD21002.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 PVD21002.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PVD21002.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD21002.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PVD21002.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 PVD21002.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PVD21002.1 - 0.011 15.7 0.2 0.025 14.5 0.2 1.7 1 1 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 PVD21002.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 PVD21002.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 PVD21002.1 - 0.024 14.5 0.2 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 PVD21002.1 - 0.025 13.8 0.0 0.055 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 PVD21002.1 - 0.039 13.1 0.0 0.89 8.6 0.0 2.3 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 PVD21002.1 - 0.047 14.2 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_19 PF13245.6 PVD21002.1 - 0.048 14.0 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PVD21002.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PVD21002.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PVD21002.1 - 0.061 13.2 0.3 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 PVD21002.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IPT PF01745.16 PVD21002.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase PduV-EutP PF10662.9 PVD21002.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 PVD21002.1 - 0.12 11.8 0.0 0.48 9.8 0.0 2.0 3 0 0 3 3 2 0 PhoH-like protein AAA_17 PF13207.6 PVD21002.1 - 0.21 12.0 0.1 0.83 10.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.25 PVD21003.1 - 2.2e-42 145.2 0.0 5.2e-41 140.7 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21003.1 - 4.6e-24 85.1 0.0 2.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase dsrm PF00035.26 PVD21003.1 - 4.4e-17 62.5 0.1 1.6e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 PVD21003.1 - 0.00066 19.8 0.3 0.065 13.4 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain LIX1 PF14954.6 PVD21003.1 - 0.0094 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Limb expression 1 Choline_kinase PF01633.20 PVD21003.1 - 0.029 14.0 0.1 0.063 12.9 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 PVD21003.1 - 0.038 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PVD21003.1 - 0.13 11.9 0.4 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PVD21003.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.6 PVD21004.1 - 6.5e-35 118.7 57.7 1.3e-07 31.3 4.2 9.0 6 3 2 8 8 8 7 Leucine rich repeat PP2C PF00481.21 PVD21004.1 - 3.6e-29 102.2 0.1 2.5e-28 99.4 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 PVD21004.1 - 4.2e-27 93.7 54.7 1.6e-05 25.1 0.7 11.5 9 3 2 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD21004.1 - 0.0012 18.3 22.6 0.016 14.7 2.4 4.6 2 2 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 PVD21004.1 - 0.0023 17.8 45.9 1.9 8.7 0.0 12.3 13 0 0 13 13 13 2 Leucine Rich repeat PH PF00169.29 PVD21004.1 - 0.061 13.8 0.0 0.26 11.8 0.0 2.0 1 1 0 1 1 1 0 PH domain LuxS PF02664.15 PVD21004.1 - 0.16 11.6 0.2 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) LRR_1 PF00560.33 PVD21004.1 - 0.2 12.3 49.2 13 6.8 0.2 14.5 16 2 1 17 17 17 0 Leucine Rich Repeat LRR_5 PF13306.6 PVD21004.1 - 0.26 11.2 0.7 1.2 9.1 0.3 2.3 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DUF4641 PF15483.6 PVD21010.1 - 0.00023 20.4 1.7 0.0005 19.3 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4641) Herpes_US9 PF06072.11 PVD21011.1 - 0.02 14.8 2.8 0.043 13.7 2.8 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Mfa_like_2 PF15415.6 PVD21011.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin-like Abhydrolase_1 PF00561.20 PVD21013.1 - 1.7e-22 80.3 0.3 3.8e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD21013.1 - 9.7e-17 62.3 0.5 1.5e-16 61.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD21013.1 - 1.5e-12 47.4 0.0 2.3e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PVD21013.1 - 0.0023 16.7 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family LIDHydrolase PF10230.9 PVD21013.1 - 0.025 14.1 0.0 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 PVD21013.1 - 0.028 14.1 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 PVD21013.1 - 0.15 12.2 0.0 0.73 9.9 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 PVD21013.1 - 0.19 11.0 0.1 1.1 8.5 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) FAM163 PF15069.6 PVD21015.1 - 0.0075 16.7 3.7 0.01 16.3 3.7 1.2 1 0 0 1 1 1 1 FAM163 family Orthoreo_P10 PF07204.11 PVD21015.1 - 0.014 15.3 0.3 0.032 14.2 0.3 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 PVD21015.1 - 0.043 14.1 8.0 0.022 15.0 5.9 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 PVD21015.1 - 0.071 14.0 1.4 0.13 13.1 1.4 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 PVD21015.1 - 0.092 12.8 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region TMEM154 PF15102.6 PVD21016.1 - 0.04 13.8 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family GvpO PF05800.11 PVD21018.1 - 0.05 13.6 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Kinesin PF00225.23 PVD21021.1 - 6e-53 179.9 0.0 4.6e-51 173.7 0.0 2.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD21021.1 - 5.4e-14 52.4 0.8 3.5e-13 49.7 0.0 2.8 3 0 0 3 3 3 1 Microtubule binding Yuri_gagarin PF15934.5 PVD21021.1 - 0.0023 17.8 1.0 0.0023 17.8 1.0 4.3 2 1 2 4 4 4 1 Yuri gagarin Occludin_ELL PF07303.13 PVD21021.1 - 0.025 15.3 4.5 0.025 15.3 4.5 5.5 3 1 3 6 6 6 0 Occludin homology domain Transthyretin PF00576.21 PVD21021.1 - 0.045 14.4 0.5 0.2 12.4 0.4 2.3 1 1 0 1 1 1 0 HIUase/Transthyretin family Fib_alpha PF08702.10 PVD21021.1 - 2.3 8.4 51.7 0.31 11.2 6.7 5.5 3 1 1 5 5 5 0 Fibrinogen alpha/beta chain family DUF4633 PF15464.6 PVD21021.1 - 2.9 8.1 9.0 9.5 6.4 0.5 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4633) SMODS PF18144.1 PVD21022.1 - 0.21 11.7 0.0 0.24 11.6 0.0 1.1 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain SUIM_assoc PF16619.5 PVD21024.1 - 0.026 14.6 2.6 0.044 13.9 2.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glycoprotein_G PF00802.19 PVD21024.1 - 0.067 12.6 1.6 0.066 12.6 1.6 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Glyco_hydro_20 PF00728.22 PVD21026.1 - 4.4e-33 115.1 0.0 7e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4293 PF14126.6 PVD21026.1 - 0.0059 16.9 2.3 0.0093 16.2 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) DUF3382 PF11862.8 PVD21026.1 - 0.035 14.4 1.3 0.07 13.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) YfhO PF09586.10 PVD21026.1 - 0.06 11.6 0.3 0.083 11.1 0.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1772 PF08592.11 PVD21026.1 - 0.086 13.2 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Wzy_C_2 PF11846.8 PVD21026.1 - 0.16 11.9 1.4 0.3 11.0 1.4 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal HemY_N PF07219.13 PVD21026.1 - 2.2 8.5 5.3 24 5.2 0.1 2.3 1 1 1 2 2 2 0 HemY protein N-terminus DUF4207 PF13904.6 PVD21027.1 - 3e-08 33.7 48.7 0.036 13.8 21.0 4.0 1 1 3 4 4 4 4 Domain of unknown function (DUF4207) RecQ5 PF06959.11 PVD21027.1 - 0.5 10.3 7.6 0.19 11.7 0.5 2.3 2 0 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) TilS PF09179.11 PVD21029.1 - 0.042 14.3 0.6 0.11 13.0 0.6 1.8 1 0 0 1 1 1 0 TilS substrate binding domain Swi3 PF07962.12 PVD21029.1 - 0.12 12.4 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 7tm_1 PF00001.21 PVD21030.1 - 8e-18 64.7 6.6 3.7e-17 62.5 6.6 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD21031.1 - 7.9e-20 71.3 2.4 1.4e-19 70.5 2.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HD PF01966.22 PVD21032.1 - 3.4e-12 46.7 0.0 9.8e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 HD domain SAM_1 PF00536.30 PVD21032.1 - 3.5e-09 37.0 0.1 1e-08 35.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD21032.1 - 4.3e-07 29.9 1.9 7.4e-07 29.2 0.1 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.19 PVD21032.1 - 0.0011 18.8 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PVD21033.1 - 5.4e-40 136.4 2.5 4.1e-13 49.6 0.0 4.5 3 1 1 4 4 4 3 HD domain PDEase_I PF00233.19 PVD21033.1 - 2e-10 40.8 8.3 0.0069 16.1 0.1 3.8 3 0 0 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 PVD21033.1 - 0.00072 19.1 0.0 1.7 8.1 0.0 3.3 3 0 0 3 3 3 2 HDOD domain Guanylate_cyc PF00211.20 PVD21033.1 - 0.013 15.1 0.0 11 5.6 0.0 3.3 3 0 0 3 3 3 0 Adenylate and Guanylate cyclase catalytic domain HD PF01966.22 PVD21034.1 - 9.6e-29 100.1 0.2 6e-13 49.1 0.1 3.0 2 0 0 2 2 2 2 HD domain PDEase_I PF00233.19 PVD21034.1 - 2.8e-05 24.0 12.8 0.00072 19.3 0.2 3.4 4 0 0 4 4 4 2 3'5'-cyclic nucleotide phosphodiesterase DUF1493 PF07377.12 PVD21034.1 - 0.032 14.7 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HD PF01966.22 PVD21035.1 - 6.6e-14 52.2 0.1 8.4e-13 48.6 0.0 2.6 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 PVD21035.1 - 9.4e-05 22.2 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PVD21036.1 - 1.2e-21 77.1 0.0 1.1e-13 51.5 0.0 2.9 2 0 0 2 2 2 2 HD domain PDEase_I PF00233.19 PVD21036.1 - 2.1e-06 27.7 1.7 0.0016 18.2 0.2 2.9 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase MSP7_C PF12948.7 PVD21036.1 - 0.021 15.5 3.3 1.3 9.7 0.0 3.9 3 1 0 3 3 3 0 MSP7-like protein C-terminal domain VWC PF00093.18 PVD21037.1 - 8.8e-25 86.8 655.6 0.0027 18.0 15.1 30.8 31 1 0 31 31 31 28 von Willebrand factor type C domain ShK PF01549.24 PVD21037.1 - 7.8e-06 26.3 86.3 0.00034 21.1 8.6 10.9 8 0 0 8 8 8 4 ShK domain-like AMP-binding PF00501.28 PVD21038.1 - 5.3e-55 186.7 0.7 1.4e-54 185.3 0.5 1.7 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD21038.1 - 1.3e-12 48.5 0.0 2.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UCH PF00443.29 PVD21039.1 - 2.2e-30 106.0 0.0 2.6e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD21039.1 - 1.3e-10 41.4 0.0 1.8e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RsbRD_N PF14361.6 PVD21039.1 - 6.6e-05 23.6 0.1 0.00056 20.6 0.1 2.3 2 0 0 2 2 2 1 RsbT co-antagonist protein rsbRD N-terminal domain bZIP_2 PF07716.15 PVD21041.1 - 1.3e-12 47.6 15.6 2.1e-12 46.9 15.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD21041.1 - 0.00014 21.9 11.8 0.00022 21.2 11.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1319 PF07028.11 PVD21041.1 - 0.016 15.4 1.9 0.022 15.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF4094 PF13334.6 PVD21041.1 - 0.15 12.5 3.1 0.26 11.7 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DivIC PF04977.15 PVD21041.1 - 0.22 11.3 5.3 0.22 11.3 4.4 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF5538 PF17692.1 PVD21042.1 - 0.0061 16.6 1.8 0.0068 16.5 1.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5538) PBP PF01161.20 PVD21043.1 - 1.5e-05 25.3 0.0 3.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAST_2 PF08368.12 PVD21044.1 - 3e-08 34.3 0.0 6.9e-07 30.0 0.0 3.0 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 PVD21044.1 - 2.8e-07 30.4 0.1 3.4e-06 26.9 0.1 2.7 1 1 1 2 2 2 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 PVD21044.1 - 6e-07 29.5 0.0 2.7e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 RAP domain Phage_TAC_5 PF08890.11 PVD21044.1 - 0.097 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC Metallophos_C PF14008.6 PVD21045.1 - 7.6e-09 36.3 0.0 2.2e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 PVD21045.1 - 3.7e-07 30.8 0.0 6.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1180 PF06679.12 PVD21045.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Herpes_gE PF02480.16 PVD21045.1 - 0.0034 16.2 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 PVD21045.1 - 0.014 15.9 0.1 0.045 14.3 0.1 1.9 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 PVD21046.1 - 8e-21 75.5 2.8 9.1e-21 75.3 1.7 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PVD21046.1 - 8.4e-17 61.8 0.0 1.9e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PVD21046.1 - 8.1e-12 45.6 0.0 1.6e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 PVD21046.1 - 0.017 15.7 0.0 0.074 13.6 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain zf-C2H2_4 PF13894.6 PVD21047.1 - 3.6e-38 126.9 83.8 0.0012 19.5 3.6 13.6 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21047.1 - 3.6e-28 96.4 81.8 6.6e-05 23.1 0.7 13.2 13 0 0 13 13 13 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD21047.1 - 2.7e-27 93.9 73.3 3.1e-06 27.4 0.3 14.1 15 0 0 15 15 14 8 Zinc-finger double domain zf-Di19 PF05605.12 PVD21047.1 - 8e-18 64.5 63.1 3.9e-07 30.3 3.5 7.5 6 1 0 7 7 7 6 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PVD21047.1 - 1e-09 38.1 96.3 2.8e-05 24.0 0.8 13.1 13 1 0 13 13 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21047.1 - 1.7e-08 34.6 79.1 0.0018 18.5 0.3 11.4 13 0 0 13 13 12 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD21047.1 - 3.7e-08 33.5 76.7 0.00058 20.2 3.4 12.6 12 0 0 12 12 12 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD21047.1 - 1e-05 25.8 77.5 0.5 10.7 1.7 12.6 1 1 10 11 11 11 4 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 PVD21047.1 - 0.003 17.8 53.7 0.057 13.7 4.4 7.0 1 1 6 7 7 7 3 C2H2-type zinc ribbon Zn-C2H2_12 PF18112.1 PVD21047.1 - 0.014 15.9 2.7 0.11 12.9 0.2 10.1 12 0 0 12 12 11 0 Autophagy receptor zinc finger-C2H2 domain DUF5319 PF17252.2 PVD21047.1 - 0.21 11.8 1.4 5.8 7.2 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5319) zf-C2HC_2 PF13913.6 PVD21047.1 - 0.59 10.1 0.0 0.59 10.1 0.0 9.8 11 0 0 11 11 11 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 PVD21047.1 - 0.87 9.2 54.1 3.6 7.3 0.1 11.6 12 0 0 12 12 11 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 PVD21047.1 - 1.3 8.9 11.3 0.26 11.1 0.2 4.1 3 1 1 4 4 4 0 GAGA factor Trm112p PF03966.16 PVD21047.1 - 1.7 9.2 14.7 35 5.1 0.1 5.0 2 2 1 3 3 3 0 Trm112p-like protein Rad50_zn_hook PF04423.14 PVD21047.1 - 9.4 6.2 29.5 1.7 8.5 0.0 6.4 8 1 0 8 8 8 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 PVD21048.1 - 1.8e-56 183.8 144.4 0.0062 17.3 0.3 22.6 22 0 0 22 22 22 21 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21048.1 - 7.2e-53 174.2 145.8 0.00019 21.7 1.0 22.7 22 0 0 22 22 22 18 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PVD21048.1 - 1.4e-17 63.2 124.8 0.00032 20.6 0.3 20.3 22 0 0 22 22 22 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21048.1 - 3.7e-12 46.2 107.1 0.19 12.0 0.1 20.6 22 0 0 22 22 22 10 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD21048.1 - 4.8e-10 39.4 116.9 0.015 15.7 0.5 20.3 21 0 0 21 21 21 8 Zinc-finger double domain zf-met PF12874.7 PVD21048.1 - 1.6e-06 28.3 104.4 0.0039 17.5 0.5 17.6 19 0 0 19 19 18 7 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD21048.1 - 5.2e-06 26.7 127.2 0.023 15.0 1.0 19.6 7 4 13 20 20 19 7 C2H2 type zinc-finger (2 copies) PriA_CRR PF18319.1 PVD21048.1 - 3.1e-05 23.9 7.0 0.0021 18.0 0.2 9.4 11 0 0 11 11 9 2 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_3rep PF18868.1 PVD21048.1 - 6.6e-05 23.6 78.2 0.00013 22.6 2.6 12.2 6 3 6 13 13 13 3 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 PVD21048.1 - 0.0012 19.1 134.4 0.086 13.1 3.2 13.7 10 4 4 15 15 14 8 Drought induced 19 protein (Di19), zinc-binding DUF3654 PF12376.8 PVD21048.1 - 0.36 11.0 6.8 2.2 8.5 3.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) zf-C2H2_8 PF15909.5 PVD21048.1 - 2 8.8 92.6 0.96 9.8 3.4 11.2 6 4 6 12 12 12 0 C2H2-type zinc ribbon adh_short PF00106.25 PVD21049.1 - 1.2e-22 80.4 0.0 7.4e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase WW PF00397.26 PVD21049.1 - 4.7e-17 61.8 1.5 6.3e-09 35.8 0.9 2.5 2 0 0 2 2 2 2 WW domain adh_short_C2 PF13561.6 PVD21049.1 - 7.1e-14 51.9 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD21049.1 - 3e-08 33.8 0.1 4.5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD21049.1 - 0.00054 19.5 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family bZIP_Maf PF03131.17 PVD21051.1 - 2.2e-28 98.6 9.2 3.3e-28 98.0 9.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PVD21051.1 - 0.00035 20.6 7.9 0.00073 19.6 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper HOOK PF05622.12 PVD21051.1 - 0.0088 14.3 1.9 0.014 13.6 1.9 1.2 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 PVD21051.1 - 0.018 15.1 11.3 0.045 13.9 11.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF1192 PF06698.11 PVD21051.1 - 0.15 12.1 0.5 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) zf-CCCH PF00642.24 PVD21052.1 - 3e-11 42.9 25.5 0.0014 18.4 3.6 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PVD21052.1 - 0.00098 19.3 8.9 0.00098 19.3 8.9 4.7 4 1 1 5 5 5 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 PVD21052.1 - 0.0012 18.9 35.9 0.89 9.7 8.1 6.8 5 2 0 5 5 5 4 Zinc finger domain Torus PF16131.5 PVD21052.1 - 0.0017 19.1 48.4 0.0026 18.4 2.4 7.7 4 1 4 8 8 8 4 Torus domain Cellulose_synt PF03552.14 PVD21052.1 - 0.015 13.8 0.2 0.032 12.8 0.2 1.5 1 0 0 1 1 1 0 Cellulose synthase zf-C3H1 PF10650.9 PVD21052.1 - 0.077 12.7 0.4 4.2 7.2 0.2 2.9 2 0 0 2 2 2 0 Putative zinc-finger domain UQ_con PF00179.26 PVD21053.1 - 2.3e-16 59.7 0.0 2.6e-15 56.3 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PVD21053.1 - 3e-05 24.3 0.0 7.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 RWD domain NusA_N PF08529.11 PVD21053.1 - 0.0072 16.7 0.7 0.012 16.0 0.7 1.3 1 0 0 1 1 1 1 NusA N-terminal domain DNA_pol_phi PF04931.13 PVD21053.1 - 0.01 14.0 5.2 0.014 13.6 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Prok-E2_B PF14461.6 PVD21053.1 - 0.054 13.2 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF2457 PF10446.9 PVD21053.1 - 0.69 9.0 10.2 0.94 8.5 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 PVD21054.1 - 1.2e-68 231.3 0.3 1.4e-68 231.1 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21054.1 - 1.7e-18 66.8 0.1 2.4e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD21054.1 - 4.6e-07 30.0 0.0 8.8e-06 25.8 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD21054.1 - 5.3e-05 22.7 0.1 8.1e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PVD21054.1 - 0.0023 16.8 0.1 0.021 13.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 PVD21054.1 - 0.0042 16.7 0.2 0.01 15.4 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PVD21054.1 - 0.081 12.5 0.4 1.6 8.3 0.1 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TSP_1 PF00090.19 PVD21055.1 - 2.2e-33 114.2 100.0 5e-12 45.8 10.4 8.5 8 0 0 8 8 8 5 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 PVD21055.1 - 5.7e-30 103.7 0.0 9.4e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 PVD21055.1 - 3.6e-29 102.1 0.1 3.6e-29 102.1 0.1 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 PVD21055.1 - 1.1e-25 90.5 0.1 2.8e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 PVD21055.1 - 4.4e-20 72.0 8.6 4.4e-20 72.0 8.6 8.1 5 3 2 7 7 3 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 PVD21055.1 - 7.5e-15 55.6 0.7 7.5e-15 55.6 0.7 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD21055.1 - 2.2e-10 41.1 0.0 4.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD21055.1 - 6.4e-10 39.2 2.2 6.5e-10 39.2 0.2 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 PVD21055.1 - 4.1e-09 37.0 10.8 4.1e-09 37.0 10.8 4.9 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.6 PVD21055.1 - 0.00028 20.6 0.9 0.00085 19.0 0.9 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TEX29 PF15839.5 PVD21055.1 - 0.67 10.6 3.5 14 6.4 0.3 2.8 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein Tubulin PF00091.25 PVD21056.1 - 8.2e-66 222.0 0.1 1.9e-43 148.9 0.0 3.0 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD21056.1 - 1.3e-05 25.0 0.0 0.0087 15.7 0.0 2.4 2 0 0 2 2 2 2 Tubulin domain Tubulin_2 PF13809.6 PVD21056.1 - 7.9e-05 22.0 0.4 0.13 11.5 0.0 2.1 2 0 0 2 2 2 2 Tubulin like Hydrolase_4 PF12146.8 PVD21056.1 - 0.094 12.0 0.0 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 JmjN PF02375.17 PVD21057.1 - 4.4e-15 55.4 1.0 1e-14 54.2 1.0 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 PVD21057.1 - 5.6e-12 46.2 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 PVD21057.1 - 1.3e-09 38.3 4.0 3.4e-09 37.0 4.0 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger JmjC PF02373.22 PVD21057.1 - 2.7e-09 37.5 0.1 2.7e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Gpi16 PF04113.14 PVD21058.1 - 5.2e-85 286.0 1.9 8.5e-42 143.3 0.7 3.1 1 1 2 3 3 3 3 Gpi16 subunit, GPI transamidase component HMG_box PF00505.19 PVD21059.1 - 3.4e-18 65.8 3.0 7e-18 64.8 3.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box zf-CW PF07496.15 PVD21059.1 - 3.3e-12 46.2 3.3 3.3e-12 46.2 3.3 3.0 3 0 0 3 3 3 1 CW-type Zinc Finger HMG_box_2 PF09011.10 PVD21059.1 - 8.7e-09 35.9 1.5 8.7e-09 35.9 1.5 2.0 2 0 0 2 2 2 1 HMG-box domain Ndr PF03096.14 PVD21060.1 - 1.2e-95 319.5 0.0 3.1e-95 318.1 0.0 1.7 1 1 0 1 1 1 1 Ndr family BCNT PF07572.12 PVD21060.1 - 3.3e-28 97.6 1.7 2.2e-27 94.9 1.4 2.4 2 0 0 2 2 2 1 Bucentaur or craniofacial development Abhydrolase_6 PF12697.7 PVD21060.1 - 2.3e-05 25.1 0.0 3.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD21060.1 - 0.00035 20.3 0.1 0.00068 19.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD21060.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4461 PF14688.6 PVD21061.1 - 1.1e-90 304.6 2.5 1.3e-90 304.4 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) UPF0184 PF03670.13 PVD21061.1 - 0.096 13.1 3.2 43 4.6 0.0 3.6 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) Anillin PF08174.11 PVD21062.1 - 1.9e-23 83.4 0.0 6.1e-23 81.8 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 PVD21062.1 - 5.7e-17 62.1 0.1 2e-16 60.4 0.1 2.0 1 0 0 1 1 1 1 PH domain Anillin_N PF16018.5 PVD21062.1 - 4.4e-09 36.8 0.5 4.4e-09 36.8 0.5 4.4 4 0 0 4 4 4 1 Anillin N-terminus PH_11 PF15413.6 PVD21062.1 - 0.0006 20.2 0.0 0.0021 18.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain G-alpha PF00503.20 PVD21063.1 - 3.9e-125 417.7 5.7 4.5e-125 417.5 5.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD21063.1 - 1.3e-17 63.8 2.6 3e-13 49.6 0.7 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD21063.1 - 2e-05 24.0 7.1 0.00049 19.5 2.9 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD21063.1 - 0.00063 20.0 3.3 0.3 11.3 0.1 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 PVD21063.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Ras PF00071.22 PVD21063.1 - 0.013 15.1 3.8 0.27 10.8 1.3 2.3 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 PVD21063.1 - 0.073 12.8 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 PVD21064.1 - 6.6e-11 42.6 15.3 1.7e-06 28.6 0.6 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 PVD21064.1 - 6.4e-10 38.5 14.5 6.4e-10 38.5 14.5 3.0 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 PVD21064.1 - 9.2e-07 29.1 5.4 9.2e-07 29.1 5.4 2.9 2 1 1 3 3 3 1 Zinc-ribbon like family DREV PF05219.12 PVD21065.1 - 7.6e-72 241.6 0.0 1.1e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 PVD21065.1 - 6.8e-12 45.5 0.0 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD21065.1 - 6.6e-10 39.6 0.0 2.4e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD21065.1 - 6.2e-06 26.8 0.0 2.1e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD21065.1 - 1.1e-05 26.0 0.0 2.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ARS2 PF04959.13 PVD21065.1 - 0.0011 19.4 0.7 0.0025 18.2 0.7 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 RrnaAD PF00398.20 PVD21065.1 - 0.0037 16.4 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase zf-C2H2_jaz PF12171.8 PVD21065.1 - 0.029 14.7 0.8 0.092 13.1 0.8 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Methyltransf_31 PF13847.6 PVD21065.1 - 0.04 13.7 0.0 0.43 10.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.26 PVD21065.1 - 0.059 13.8 1.1 0.25 11.9 1.1 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Prim_Zn_Ribbon PF08273.12 PVD21065.1 - 0.13 12.5 1.0 0.43 10.9 0.5 2.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase ADK_lid PF05191.14 PVD21065.1 - 0.16 12.0 0.9 0.68 10.0 0.9 2.2 1 0 0 1 1 1 0 Adenylate kinase, active site lid Homeodomain PF00046.29 PVD21066.1 - 4.9e-44 148.0 32.9 1e-17 63.7 0.6 6.3 7 0 0 7 7 7 3 Homeodomain zf-C2H2_4 PF13894.6 PVD21066.1 - 1.1e-16 60.1 98.0 0.0036 18.0 1.0 15.8 15 0 0 15 15 15 9 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21066.1 - 1.1e-11 44.5 106.8 0.023 15.1 0.2 15.2 15 0 0 15 15 14 9 Zinc finger, C2H2 type Homeobox_KN PF05920.11 PVD21066.1 - 6.6e-11 41.9 5.5 0.0018 18.2 0.0 3.8 3 0 0 3 3 3 3 Homeobox KN domain zf-C2H2_6 PF13912.6 PVD21066.1 - 2.6e-06 27.3 6.7 6.6e-05 22.8 0.7 12.5 14 0 0 14 14 14 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD21066.1 - 0.011 16.5 40.7 8.8 7.0 0.1 10.1 8 2 2 10 10 10 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 PVD21066.1 - 0.028 14.7 72.5 0.44 10.9 0.3 13.5 10 3 2 14 14 14 0 C2H2 type zinc-finger (2 copies) Homez PF11569.8 PVD21066.1 - 0.046 13.2 1.8 3.2 7.3 0.2 3.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez MerR_1 PF13411.6 PVD21066.1 - 0.078 13.1 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein zf-C2H2_jaz PF12171.8 PVD21066.1 - 0.11 12.8 59.3 1.7 9.0 0.6 10.8 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PVD21066.1 - 1.2 9.0 6.6 17 5.3 0.0 4.0 4 0 0 4 4 3 0 GAGA factor OrsD PF12013.8 PVD21066.1 - 9.9 6.6 42.0 0.17 12.4 1.4 9.1 9 2 1 10 10 10 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 PVD21068.1 - 6.7e-06 26.5 60.9 0.43 11.5 1.8 10.7 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21068.1 - 7.5e-05 23.0 68.6 0.0023 18.3 0.7 10.9 10 0 0 10 10 10 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD21068.1 - 8.5e-05 22.2 1.3 8.5e-05 22.2 1.3 6.7 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-met PF12874.7 PVD21068.1 - 0.00011 22.4 1.1 0.00011 22.4 1.1 8.5 9 0 0 9 9 8 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD21068.1 - 0.039 14.0 0.2 0.039 14.0 0.2 5.2 6 0 0 6 6 5 0 C2H2-type zinc finger AKAP95 PF04988.12 PVD21068.1 - 0.047 13.9 34.5 0.15 12.3 0.4 6.4 7 0 0 7 7 7 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_10 PF18414.1 PVD21068.1 - 0.054 13.0 0.8 9.3 5.9 0.1 3.7 2 0 0 2 2 2 0 C2H2 type zinc-finger GAGA PF09237.11 PVD21068.1 - 0.078 12.8 1.8 14 5.6 0.0 3.1 3 0 0 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 PVD21068.1 - 0.22 11.9 72.7 0.47 10.8 0.8 10.0 6 2 2 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 PVD21068.1 - 0.3 11.8 29.1 4.1 8.1 0.8 6.7 6 1 1 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 PVD21068.1 - 3.9 7.5 9.4 2.2 8.3 0.3 4.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type CYTH PF01928.21 PVD21069.1 - 3.8e-08 33.5 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 CYTH domain DUF2046 PF09755.9 PVD21070.1 - 0.0015 17.8 30.5 0.0015 17.8 30.5 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1515 PF07439.11 PVD21070.1 - 0.0083 16.1 0.4 0.0083 16.1 0.4 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1515) PSI_PsaF PF02507.15 PVD21070.1 - 0.81 9.5 4.2 0.36 10.7 0.4 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III CENP-F_leu_zip PF10473.9 PVD21070.1 - 2 8.4 57.3 0.36 10.9 18.6 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 PVD21070.1 - 3.8 6.8 52.4 0.54 9.6 11.3 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ArAE_2_N PF10337.9 PVD21070.1 - 4.5 6.2 11.7 6 5.8 11.7 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal MitMem_reg PF13012.6 PVD21071.1 - 1.6e-36 125.1 0.9 2.6e-36 124.4 0.9 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PVD21071.1 - 1.2e-33 115.6 0.0 2.6e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 PVD21071.1 - 0.027 14.2 2.8 0.041 13.6 2.8 1.4 1 1 0 1 1 1 0 Connexin CobT PF06213.12 PVD21071.1 - 0.028 13.8 6.0 0.038 13.4 6.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 PVD21071.1 - 0.087 13.2 2.9 0.13 12.6 2.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 PVD21071.1 - 1 7.6 10.1 2.7 6.2 6.1 2.0 2 0 0 2 2 2 0 CDC45-like protein NARP1 PF12569.8 PVD21071.1 - 1.5 7.6 10.6 2 7.2 10.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FERM_f0 PF16511.5 PVD21072.1 - 0.041 14.2 0.1 9.7 6.6 0.0 3.0 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM ALF PF03752.13 PVD21072.1 - 0.11 12.5 0.2 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Short repeats of unknown function DUF667 PF05018.13 PVD21073.1 - 9.2e-95 315.6 1.0 1e-94 315.5 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) CAP_GLY PF01302.25 PVD21074.1 - 4.4e-39 132.3 4.1 2.1e-12 46.8 0.0 3.4 3 0 0 3 3 3 3 CAP-Gly domain UCH PF00443.29 PVD21074.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 PVD21075.1 - 1.3e-49 168.9 1.3 5.3e-42 144.0 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21075.1 - 7.8e-35 120.4 0.0 3.4e-30 105.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD21075.1 - 0.0087 15.4 4.7 0.12 11.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like SieB PF14163.6 PVD21075.1 - 0.61 9.6 3.7 3.2 7.2 3.7 2.2 1 1 0 1 1 1 0 Super-infection exclusion protein B Anoctamin PF04547.12 PVD21076.1 - 1.7e-111 373.3 17.7 2.1e-111 373.0 17.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PVD21076.1 - 0.0082 15.9 0.2 0.021 14.6 0.2 1.6 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF1772 PF08592.11 PVD21076.1 - 0.23 11.8 2.3 0.33 11.3 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) EII-Sor PF03609.14 PVD21076.1 - 3.4 7.0 6.9 1.7 8.0 1.3 2.5 2 1 1 3 3 3 0 PTS system sorbose-specific iic component LRR_8 PF13855.6 PVD21077.1 - 2.4e-52 174.5 59.9 9.1e-15 54.2 0.4 6.2 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PVD21077.1 - 1e-30 105.2 41.1 4.5e-07 30.1 1.3 7.3 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD21077.1 - 2.4e-14 53.4 0.1 3.8e-05 23.6 0.0 3.5 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD21077.1 - 1.4e-11 43.3 41.8 0.95 10.3 1.3 12.1 11 2 0 11 11 11 5 Leucine Rich Repeat LRR_9 PF14580.6 PVD21077.1 - 5e-10 39.2 10.9 0.0048 16.4 0.5 3.5 2 2 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 PVD21077.1 - 1.8e-09 36.9 39.9 0.0087 16.0 0.3 11.0 12 0 0 12 12 12 4 Leucine Rich repeat LRR_2 PF07723.13 PVD21077.1 - 5.6 7.8 9.1 11 6.9 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat TMEM70 PF06979.12 PVD21078.1 - 8.3e-41 139.5 0.7 1.9e-40 138.3 0.3 1.8 3 1 1 4 4 4 1 Assembly, mitochondrial proton-transport ATP synth complex Pkinase PF00069.25 PVD21079.1 - 2.6e-35 122.1 0.2 3.6e-35 121.6 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21079.1 - 1.9e-23 83.1 0.3 1.6e-15 57.1 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase PKcGMP_CC PF16808.5 PVD21079.1 - 3.6e-06 26.7 0.6 3.6e-06 26.7 0.6 2.6 2 1 1 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinase-like PF14531.6 PVD21079.1 - 5.1e-05 22.7 0.1 0.00011 21.7 0.1 1.5 2 0 0 2 2 2 1 Kinase-like TMF_DNA_bd PF12329.8 PVD21079.1 - 0.0021 18.0 7.2 0.0046 16.9 7.2 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Kdo PF06293.14 PVD21079.1 - 0.0021 17.4 0.2 0.004 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HMMR_N PF15905.5 PVD21079.1 - 0.0049 16.4 4.7 0.012 15.2 4.1 1.7 1 1 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal NYD-SP28 PF14772.6 PVD21079.1 - 0.0084 16.1 1.1 0.0084 16.1 1.1 2.1 2 0 0 2 2 2 1 Sperm tail DUF641 PF04859.12 PVD21079.1 - 0.017 15.4 0.7 0.033 14.5 0.7 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Haspin_kinase PF12330.8 PVD21079.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Med4 PF10018.9 PVD21079.1 - 0.072 12.8 1.0 0.13 11.9 1.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 XLF PF09302.11 PVD21079.1 - 0.076 13.2 0.6 0.13 12.4 0.1 1.6 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF16 PF01519.16 PVD21079.1 - 0.082 13.4 1.3 0.23 12.0 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 PVD21079.1 - 0.094 12.1 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RIO1 PF01163.22 PVD21079.1 - 0.099 12.2 0.1 0.099 12.2 0.1 1.7 2 0 0 2 2 2 0 RIO1 family DASH_Dad2 PF08654.10 PVD21079.1 - 0.28 11.6 3.3 4 7.9 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 APH PF01636.23 PVD21079.1 - 0.31 10.9 1.2 0.36 10.7 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Angiomotin_C PF12240.8 PVD21079.1 - 0.31 10.6 5.7 0.27 10.8 0.7 2.1 2 0 0 2 2 2 0 Angiomotin C terminal SlyX PF04102.12 PVD21079.1 - 0.43 11.2 4.6 0.25 12.0 1.7 2.0 2 0 0 2 2 2 0 SlyX Med21 PF11221.8 PVD21079.1 - 2.2 8.5 6.4 7.4 6.8 4.6 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Pkinase PF00069.25 PVD21080.1 - 2.9e-13 49.8 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21080.1 - 5.3e-05 22.6 0.0 9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LPD18 PF18832.1 PVD21080.1 - 0.055 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 RVT_1 PF00078.27 PVD21081.1 - 1.3e-16 60.8 0.1 8.7e-11 41.8 0.0 2.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 PVD21082.1 - 7.8e-151 491.0 43.3 6.4e-19 68.2 0.0 16.5 16 1 0 16 16 15 14 Cadherin domain Laminin_G_2 PF02210.24 PVD21082.1 - 2.5e-46 157.3 1.6 3.3e-23 82.6 0.0 2.9 3 0 0 3 3 2 2 Laminin G domain Cadherin_C PF01049.17 PVD21082.1 - 3e-44 150.9 4.2 3.7e-44 150.6 2.6 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic region Laminin_G_1 PF00054.23 PVD21082.1 - 2e-33 115.4 0.0 3.5e-16 59.6 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 PVD21082.1 - 4.9e-11 42.7 43.2 3.5e-05 24.0 4.7 4.8 4 0 0 4 4 4 4 EGF-like domain Cadherin_3 PF16184.5 PVD21082.1 - 1.7e-07 31.2 22.6 2 8.5 0.1 10.0 9 1 1 10 10 10 3 Cadherin-like hEGF PF12661.7 PVD21082.1 - 0.0005 20.6 41.6 0.014 16.0 5.4 5.2 4 0 0 4 4 4 3 Human growth factor-like EGF Cadherin_2 PF08266.12 PVD21082.1 - 0.00071 19.4 0.1 23 4.9 0.0 5.7 6 0 0 6 6 6 0 Cadherin-like Laminin_G_3 PF13385.6 PVD21082.1 - 0.0019 18.4 0.1 0.33 11.1 0.1 3.5 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 PVD21082.1 - 0.0043 17.2 29.0 0.012 15.8 0.5 4.6 4 0 0 4 4 4 2 EGF domain Insulin_TMD PF17870.1 PVD21082.1 - 0.093 12.8 0.4 0.24 11.5 0.4 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF3377 PF11857.8 PVD21082.1 - 0.3 11.0 1.1 1 9.3 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) cEGF PF12662.7 PVD21082.1 - 4.8 7.2 22.9 12 5.9 0.9 5.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like CRAL_TRIO PF00650.20 PVD21083.1 - 7.1e-19 68.1 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD21083.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Arm PF00514.23 PVD21084.1 - 8.1e-16 57.5 3.2 0.0071 16.4 0.1 6.1 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD21084.1 - 1.3e-05 25.5 1.2 0.069 13.5 0.1 3.9 1 1 3 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PVD21084.1 - 0.00099 19.6 0.3 9.4 6.9 0.0 4.0 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 PVD21084.1 - 0.0098 16.1 7.1 9.7 6.8 0.1 5.1 6 0 0 6 6 6 2 HEAT repeat Rep_Org_C PF06926.11 PVD21084.1 - 0.053 13.8 0.0 4.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Ank_4 PF13637.6 PVD21085.1 - 5.8e-07 29.9 0.4 0.0091 16.6 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Arm PF00514.23 PVD21085.1 - 9.5e-07 28.7 1.9 0.003 17.5 0.0 4.0 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 PVD21085.1 - 0.00013 22.5 0.3 0.00079 20.0 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) V-ATPase_H_N PF03224.14 PVD21085.1 - 0.0017 17.7 0.0 0.021 14.1 0.0 2.2 1 1 0 1 1 1 1 V-ATPase subunit H KAP PF05804.12 PVD21085.1 - 0.024 12.8 0.0 0.036 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Ank_3 PF13606.6 PVD21085.1 - 0.064 13.8 0.0 0.51 11.1 0.0 2.6 1 0 0 1 1 1 0 Ankyrin repeat Atx10homo_assoc PF09759.9 PVD21085.1 - 0.11 12.6 2.2 0.16 12.0 0.3 2.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 PVD21085.1 - 1.5 9.3 5.0 7.6 7.1 0.0 4.5 5 2 1 6 6 6 0 HEAT repeat GSHPx PF00255.19 PVD21086.1 - 1.6e-28 98.4 0.0 2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DSPc PF00782.20 PVD21087.1 - 3.8e-33 114.1 0.0 5.1e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD21087.1 - 0.00058 19.5 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RTTN_N PF14726.6 PVD21088.1 - 2.1e-30 105.4 1.4 1.1e-29 103.0 1.4 2.4 1 0 0 1 1 1 1 Rotatin, an armadillo repeat protein, centriole functioning E1-E2_ATPase PF00122.20 PVD21089.1 - 1.4e-46 158.3 0.0 1.4e-46 158.3 0.0 3.4 3 1 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PVD21089.1 - 7.7e-45 152.8 5.7 7.7e-45 152.8 5.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PVD21089.1 - 8.5e-17 62.1 4.4 7e-16 59.1 4.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PVD21089.1 - 1e-16 60.3 0.0 2.5e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PVD21089.1 - 1.2e-14 54.1 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Attachment_P66 PF11263.8 PVD21089.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 Hydrolase_3 PF08282.12 PVD21089.1 - 0.2 11.3 1.0 0.37 10.5 1.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5592 PF17332.2 PVD21089.1 - 0.78 10.3 3.9 28 5.4 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5592) PCIF1_WW PF12237.8 PVD21090.1 - 6.7e-71 237.4 0.4 1.1e-70 236.8 0.4 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 PVD21090.1 - 1.1e-09 38.1 0.5 1.9e-09 37.4 0.5 1.4 1 0 0 1 1 1 1 WW domain Snf7 PF03357.21 PVD21091.1 - 1.9e-50 170.9 12.8 2.7e-50 170.3 12.8 1.2 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 PVD21091.1 - 0.041 14.3 3.9 0.058 13.8 3.9 1.3 1 0 0 1 1 1 0 SYF2 splicing factor LPD22 PF18834.1 PVD21091.1 - 0.047 13.9 1.1 6.4 7.1 0.7 2.6 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 V_ATPase_I PF01496.19 PVD21091.1 - 1.6 6.6 6.8 1.9 6.3 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2972 PF11186.8 PVD21092.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) DinB PF05163.12 PVD21094.1 - 0.11 12.4 5.4 0.06 13.3 1.7 2.2 2 0 0 2 2 2 0 DinB family DivIC PF04977.15 PVD21094.1 - 4.8 7.0 7.0 0.34 10.7 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Ras PF00071.22 PVD21095.1 - 1.5e-08 34.4 0.1 4.3e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PVD21095.1 - 0.0044 17.2 0.2 4.4 7.5 0.0 2.3 1 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SIR2 PF02146.17 PVD21096.1 - 2.5e-36 125.3 0.0 4e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Med27 PF11571.8 PVD21096.1 - 0.068 13.5 0.2 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 27 Septin PF00735.18 PVD21100.1 - 2.3e-120 401.1 0.0 2.3e-120 401.1 0.0 2.0 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 PVD21100.1 - 2.9e-08 33.8 0.5 8.5e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD21100.1 - 3.8e-06 26.9 5.9 1.5e-05 25.0 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 PVD21100.1 - 0.00024 20.5 0.0 0.00024 20.5 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 PVD21100.1 - 0.00043 19.9 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 PVD21100.1 - 0.0013 18.3 0.1 0.0037 16.8 0.1 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 PVD21100.1 - 0.0041 17.4 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD21100.1 - 0.0095 15.5 0.3 0.027 14.0 0.1 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 PVD21100.1 - 0.016 15.4 1.1 0.029 14.6 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PVD21100.1 - 0.017 15.5 0.4 0.033 14.6 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain Exonuc_VII_L PF02601.15 PVD21100.1 - 0.028 14.0 5.2 0.012 15.2 2.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_29 PF13555.6 PVD21100.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD21100.1 - 0.053 14.0 0.0 0.053 14.0 0.0 2.7 3 0 0 3 3 2 0 ABC transporter LOH1CR12 PF10158.9 PVD21100.1 - 0.12 12.4 4.8 0.36 10.9 4.8 1.8 1 0 0 1 1 1 0 Tumour suppressor protein LMBR1 PF04791.16 PVD21100.1 - 0.26 10.1 0.6 0.31 9.9 0.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF87 PF01935.17 PVD21100.1 - 2.4 8.2 7.4 51 3.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain GTP_EFTU PF00009.27 PVD21100.1 - 3.6 7.1 12.8 1.2 8.6 0.1 3.9 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain CUB PF00431.20 PVD21102.1 - 0.0037 17.6 0.0 0.019 15.3 0.0 1.8 1 1 1 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 PVD21103.1 - 2.8e-06 27.4 10.6 2.8e-06 27.4 10.6 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD21103.1 - 3.9e-06 27.2 0.1 2.8e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 CUB domain CD34_antigen PF06365.12 PVD21103.1 - 0.017 14.7 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.6 PVD21103.1 - 0.032 15.1 0.3 0.089 13.7 0.3 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 PVD21103.1 - 0.056 13.7 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Insulin_TMD PF17870.1 PVD21103.1 - 0.093 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vpu PF00558.19 PVD21103.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Vpu protein POPLD PF08170.12 PVD21103.1 - 2.1 8.8 4.7 7.7 6.9 2.5 2.6 2 1 0 2 2 2 0 POPLD (NUC188) domain Ctr PF04145.15 PVD21103.1 - 2.7 8.6 5.1 14 6.3 5.0 2.0 1 1 0 1 1 1 0 Ctr copper transporter family ACC_epsilon PF13822.6 PVD21103.1 - 9.9 6.9 6.5 0.98 10.1 0.1 2.5 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit CUB PF00431.20 PVD21104.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 CUB domain Ldl_recept_a PF00057.18 PVD21105.1 - 9.2e-07 29.0 8.7 9.2e-07 29.0 8.7 2.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A CYYR1 PF10873.8 PVD21105.1 - 0.0023 18.4 0.1 0.0023 18.4 0.1 3.1 2 2 1 3 3 3 1 Cysteine and tyrosine-rich protein 1 FAM163 PF15069.6 PVD21105.1 - 0.082 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 FAM163 family VSP PF03302.13 PVD21105.1 - 0.26 10.1 2.0 0.42 9.4 2.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Claudin_2 PF13903.6 PVD21106.1 - 0.041 13.6 18.6 0.46 10.2 8.4 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD21106.1 - 0.074 13.2 6.8 0.12 12.5 6.8 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein MtrF PF09472.10 PVD21106.1 - 0.086 12.2 0.5 0.38 10.2 0.1 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF4064 PF13273.6 PVD21106.1 - 4.3 7.7 8.8 0.64 10.3 4.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) PMP22_Claudin PF00822.20 PVD21107.1 - 0.0014 18.5 4.8 0.0028 17.6 4.8 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD21107.1 - 0.019 14.9 7.2 0.058 13.3 7.2 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.12 PVD21107.1 - 0.026 14.0 0.2 0.026 14.0 0.2 2.3 1 1 1 2 2 2 0 Clc-like Claudin_2 PF13903.6 PVD21107.1 - 0.19 11.5 17.7 0.062 13.1 4.8 3.1 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.23 PVD21107.1 - 5 7.2 12.6 0.45 10.5 7.5 1.9 2 0 0 2 2 2 0 Membrane-associating domain Claudin_2 PF13903.6 PVD21108.1 - 0.0072 16.1 23.8 8.3 6.1 23.8 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction YfhO PF09586.10 PVD21108.1 - 0.11 10.7 7.3 0.043 12.0 5.2 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO Neurensin PF14927.6 PVD21108.1 - 0.24 11.1 4.1 1.6 8.5 0.3 2.5 2 1 0 2 2 2 0 Neurensin Tom22 PF04281.13 PVD21108.1 - 0.71 9.7 3.9 17 5.2 1.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 WTF PF03303.13 PVD21108.1 - 5 6.8 9.4 6.1 6.5 9.4 1.4 1 1 0 1 1 1 0 WTF protein Claudin_3 PF06653.11 PVD21108.1 - 7.5 6.5 22.2 99 2.8 22.2 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 PVD21109.1 - 2.2e-05 24.4 11.1 2.8e-05 24.0 11.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 PVD21109.1 - 0.014 14.9 0.1 0.014 14.9 0.1 1.7 2 1 0 2 2 2 0 Clc-like DUF4229 PF14012.6 PVD21109.1 - 0.98 9.6 4.1 9.6 6.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) RseC_MucC PF04246.12 PVD21109.1 - 6.3 6.8 7.5 0.24 11.4 0.5 2.2 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC PMP22_Claudin PF00822.20 PVD21110.1 - 2.5e-05 24.2 10.9 3.4e-05 23.8 10.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 PVD21110.1 - 0.0058 16.1 0.6 0.0097 15.4 0.1 1.6 1 1 0 1 1 1 1 Clc-like RseC_MucC PF04246.12 PVD21110.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.4 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC PMP22_Claudin PF00822.20 PVD21111.1 - 0.00075 19.4 12.1 0.0013 18.7 12.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 PVD21111.1 - 0.01 15.3 0.9 0.015 14.8 0.1 1.6 1 1 0 1 1 1 0 Clc-like RseC_MucC PF04246.12 PVD21111.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.6 2 2 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF4229 PF14012.6 PVD21111.1 - 2.2 8.4 6.1 3 8.0 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) Copine PF07002.16 PVD21112.1 - 2.3e-86 288.8 0.0 3e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 PVD21112.1 - 1.1e-15 57.7 0.4 8e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain LSM PF01423.22 PVD21112.1 - 5.5e-06 26.0 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 LSM domain vWA-TerF-like PF10138.9 PVD21112.1 - 6.9e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 PVD21112.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FAD_binding_3 PF01494.19 PVD21113.1 - 0.00078 18.8 0.1 1.4 8.1 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 PVD21113.1 - 0.036 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 PVD21113.1 - 0.041 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD21113.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PVD21113.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD21113.1 - 0.18 11.4 0.2 0.31 10.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SK_channel PF03530.14 PVD21115.1 - 2.2e-13 50.2 4.6 6.8e-08 32.5 0.3 2.6 2 1 1 3 3 3 2 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 PVD21116.1 - 1.4e-12 47.4 2.3 3.2e-12 46.2 2.3 1.7 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 PVD21116.1 - 7.6e-08 32.3 2.7 2e-07 31.0 0.1 2.5 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 PVD21116.1 - 3.8e-07 30.2 2.7 8.2e-07 29.1 2.7 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans PF00520.31 PVD21116.1 - 0.00013 21.2 5.0 0.00025 20.3 5.0 1.5 1 1 0 1 1 1 1 Ion transport protein Mer2 PF09074.10 PVD21116.1 - 0.082 12.7 1.2 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 Mer2 MATH PF00917.26 PVD21119.1 - 6e-05 23.2 0.0 0.00032 20.8 0.1 2.0 2 0 0 2 2 2 1 MATH domain PEPCK_GTP PF00821.18 PVD21120.1 - 4.5e-100 335.0 10.2 3e-74 250.0 0.1 3.1 1 1 2 3 3 3 3 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 PVD21120.1 - 2.3e-90 302.0 0.0 3.2e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PEPCK_GTP PF00821.18 PVD21121.1 - 1.7e-141 471.2 0.0 2.1e-99 332.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 PVD21121.1 - 2.2e-92 308.6 0.0 2.9e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain zf-C2H2 PF00096.26 PVD21127.1 - 1.3e-25 88.4 32.6 2.8e-07 30.6 0.2 5.7 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21127.1 - 7.3e-21 73.1 31.9 8.6e-06 26.2 0.2 5.7 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21127.1 - 6.1e-20 70.7 29.5 6.4e-09 35.9 0.1 5.8 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD21127.1 - 8.6e-11 41.8 9.0 0.013 15.8 0.1 4.5 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD21127.1 - 1.3e-06 28.6 18.9 0.0034 17.6 0.9 4.0 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 PVD21127.1 - 0.00015 21.3 14.6 1.5 8.5 0.1 5.6 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 PVD21127.1 - 0.00018 21.4 24.7 0.25 11.4 0.3 5.9 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD21127.1 - 0.00027 20.6 16.6 0.043 13.6 0.7 5.2 5 0 0 5 5 5 1 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 PVD21127.1 - 0.0004 20.6 17.9 1.1 9.6 1.1 5.4 5 0 0 5 5 5 2 zinc-ribbon Zn-C2H2_12 PF18112.1 PVD21127.1 - 0.00094 19.6 10.3 6.2 7.4 0.0 4.7 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 PVD21127.1 - 0.0012 18.9 21.2 0.2 11.8 2.2 4.5 2 2 1 4 4 4 2 Zinc ribbon domain HypA PF01155.19 PVD21127.1 - 0.0013 18.7 12.1 0.42 10.6 1.3 3.3 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 PVD21127.1 - 0.0021 18.4 17.4 1.1 9.7 0.2 5.0 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 PVD21127.1 - 0.0079 16.1 7.0 3.6 7.6 0.0 4.6 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger zf-HYPF PF07503.12 PVD21127.1 - 0.0094 15.7 18.4 1 9.2 0.7 4.4 3 2 0 3 3 3 2 HypF finger zinc_ribbon_15 PF17032.5 PVD21127.1 - 0.015 16.0 17.0 0.092 13.5 0.5 3.1 1 1 0 2 2 2 0 zinc-ribbon family XPA_N PF01286.18 PVD21127.1 - 0.018 15.0 13.6 7.7 6.7 0.1 4.9 5 0 0 5 5 5 0 XPA protein N-terminal DZR PF12773.7 PVD21127.1 - 0.031 14.3 23.8 5.3e+03 -2.5 23.8 3.3 1 1 0 1 1 0 0 Double zinc ribbon TerY_C PF15616.6 PVD21127.1 - 0.049 13.8 1.3 0.049 13.8 1.3 3.1 1 1 2 3 3 3 0 TerY-C metal binding domain zf-ribbon_3 PF13248.6 PVD21127.1 - 0.081 12.4 20.3 1.6 8.2 0.2 4.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 PVD21127.1 - 0.11 12.3 0.1 0.11 12.3 0.1 5.6 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 PVD21127.1 - 0.16 12.0 20.7 14 5.7 0.1 5.8 6 0 0 6 6 6 0 zinc-ribbon domain Rpr2 PF04032.16 PVD21127.1 - 0.21 11.9 11.1 2.1 8.7 0.4 2.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HE PF16278.5 PVD21127.1 - 0.23 12.0 0.1 0.23 12.0 0.1 4.4 1 1 2 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 PVD21127.1 - 0.28 11.2 21.9 3.2 7.9 0.1 5.0 1 1 4 5 5 5 0 BED zinc finger ADK_lid PF05191.14 PVD21127.1 - 0.36 10.8 13.9 0.81 9.7 0.3 4.1 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-AN1 PF01428.16 PVD21127.1 - 0.4 10.9 17.4 7.9 6.7 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger C1_4 PF07975.12 PVD21127.1 - 2.5 8.4 15.0 0.14 12.4 0.8 4.0 2 1 1 4 4 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 PVD21127.1 - 3.9 7.5 29.4 0.96 9.5 7.9 4.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.10 PVD21127.1 - 4.6 8.0 13.7 3 8.6 0.1 4.8 2 2 3 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-ISL3 PF14690.6 PVD21127.1 - 5 7.9 19.2 20 6.0 0.1 5.0 5 0 0 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2225 PF09986.9 PVD21127.1 - 6 6.5 6.3 4.8 6.9 1.0 2.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) GAGA PF09237.11 PVD21127.1 - 7.6 6.4 10.5 1.7 8.6 0.1 3.1 2 2 1 3 3 3 0 GAGA factor zinc_ribbon_2 PF13240.6 PVD21127.1 - 7.8 6.4 22.3 13 5.7 0.3 5.3 5 0 0 5 5 5 0 zinc-ribbon domain CpXC PF14353.6 PVD21127.1 - 8.9 6.4 21.2 10 6.2 0.2 5.3 2 1 3 5 5 4 0 CpXC protein RRM_1 PF00076.22 PVD21129.1 - 7.9e-10 38.4 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 PVD21129.1 - 0.0021 18.7 8.0 0.58 11.2 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger RRM_5 PF13893.6 PVD21129.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_11 PF16622.5 PVD21129.1 - 0.025 14.3 5.7 1.1 9.1 0.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 PVD21129.1 - 0.045 14.4 1.1 7.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 PVD21129.1 - 0.057 13.8 0.4 0.057 13.8 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.6 PVD21129.1 - 0.059 12.8 0.8 0.14 11.6 0.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 PVD21129.1 - 0.13 12.8 7.0 0.39 11.3 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_15 PF17032.5 PVD21129.1 - 0.42 11.4 5.7 1.5 9.6 5.7 1.9 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_9 PF16293.5 PVD21129.1 - 0.5 10.3 6.0 0.58 10.0 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 PVD21129.1 - 1.4 9.3 8.1 12 6.3 0.7 2.2 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 PVD21129.1 - 2.4 8.5 6.4 2 8.8 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PVD21129.1 - 3.3 7.8 10.7 1 9.4 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4pol PF14260.6 PVD21129.1 - 5 7.7 7.9 1.7 9.2 1.1 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 PVD21129.1 - 6.5 6.9 8.6 20 5.3 8.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 PVD21129.1 - 8.7 6.8 6.8 4.4 7.7 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PVD21130.1 - 6.1e-37 124.0 143.5 0.00015 22.1 1.6 17.6 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21130.1 - 7.8e-35 116.5 143.6 0.0032 18.2 0.8 18.0 18 0 0 18 18 18 15 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21130.1 - 3.9e-23 80.8 123.9 2.9e-05 24.3 0.8 18.0 19 1 0 19 19 19 10 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD21130.1 - 0.00018 21.4 9.4 0.0012 18.8 0.7 15.6 15 2 1 16 16 16 8 C2H2-type zinc finger zf-Di19 PF05605.12 PVD21130.1 - 0.00076 19.7 2.1 0.00076 19.7 2.1 11.3 7 3 4 12 12 12 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 PVD21130.1 - 0.0043 17.4 0.5 0.0043 17.4 0.5 13.5 16 0 0 16 16 13 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD21130.1 - 0.011 15.5 0.5 0.011 15.5 0.5 13.0 16 0 0 16 16 15 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PVD21130.1 - 0.023 15.1 0.7 0.023 15.1 0.7 15.3 6 4 11 17 17 17 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PVD21130.1 - 0.028 14.5 0.9 0.028 14.5 0.9 11.9 11 2 2 13 13 12 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 PVD21130.1 - 0.074 13.4 0.2 0.074 13.4 0.2 16.3 18 0 0 18 18 18 0 Zinc-finger double-stranded RNA-binding DUF3797 PF12677.7 PVD21130.1 - 0.57 10.1 7.0 1.5 8.8 0.4 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) BolA PF01722.18 PVD21130.1 - 2 8.7 6.5 9.8 6.5 0.6 4.1 4 0 0 4 4 4 0 BolA-like protein zf-C2H2_4 PF13894.6 PVD21131.1 - 9.5e-27 91.4 154.0 0.019 15.7 0.5 22.8 23 0 0 23 23 23 14 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21131.1 - 1.7e-18 66.0 145.2 0.001 19.4 1.9 21.1 21 1 0 21 21 21 13 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD21131.1 - 4.8e-17 61.5 133.8 0.00079 19.7 0.6 19.3 22 0 0 22 22 22 10 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD21131.1 - 0.00056 19.8 1.8 0.00056 19.8 1.8 15.0 16 0 0 16 16 16 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD21131.1 - 0.0013 19.0 4.0 0.0013 19.0 4.0 9.0 7 1 3 10 10 10 2 C2H2-type zinc ribbon zf_C2H2_10 PF18414.1 PVD21131.1 - 1.5 8.4 8.5 0.18 11.3 0.3 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger HEPN_Toprim_N PF18871.1 PVD21131.1 - 4.4 7.2 7.9 1.6 8.6 2.2 2.6 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 zf-C2H2_4 PF13894.6 PVD21132.1 - 9.9e-13 47.8 82.3 0.0008 20.1 1.6 12.5 13 0 0 13 13 13 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21132.1 - 1.3e-06 28.5 14.9 0.00054 20.3 0.5 11.4 13 0 0 13 13 13 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21132.1 - 8.3e-05 22.8 89.5 0.037 14.5 1.7 11.6 13 0 0 13 13 13 7 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 PVD21132.1 - 0.14 12.0 0.1 0.14 12.0 0.1 6.8 7 1 0 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 PVD21132.1 - 0.28 11.5 0.1 0.28 11.5 0.1 5.6 2 2 4 6 6 6 0 C2H2-type zinc ribbon YdjO PF14169.6 PVD21132.1 - 0.45 10.3 5.8 3.4 7.5 0.3 4.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-C2H2_6 PF13912.6 PVD21132.1 - 1.2 9.2 42.3 3.8 7.6 0.7 8.9 8 0 0 8 8 8 0 C2H2-type zinc finger GAGA PF09237.11 PVD21132.1 - 4.6 7.1 0.0 4.6 7.1 0.0 3.6 3 1 0 3 3 3 0 GAGA factor zf-C2H2_4 PF13894.6 PVD21133.1 - 2.3e-21 74.6 116.5 0.001 19.7 3.8 13.7 13 0 0 13 13 13 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21133.1 - 2.2e-10 40.5 91.0 0.00023 21.4 6.9 11.1 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21133.1 - 8.7e-09 35.4 115.9 4.5e-05 23.7 0.7 13.2 13 0 0 13 13 13 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD21133.1 - 0.00068 19.9 7.9 0.0039 17.5 0.9 12.0 12 1 1 13 13 13 5 Zinc-finger double-stranded RNA-binding Ribosomal_L22e PF01776.17 PVD21133.1 - 0.04 14.3 0.3 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L22e protein family zf-C2H2_4 PF13894.6 PVD21134.1 - 9.2e-08 32.3 72.1 0.13 13.2 1.2 10.6 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD21134.1 - 2.7e-05 24.8 32.4 0.042 14.5 10.8 4.8 3 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats DUF4428 PF14471.6 PVD21134.1 - 3.3 7.7 9.2 3.5 7.6 1.8 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4428) zf-MYST PF17772.1 PVD21134.1 - 8.6 6.0 29.2 22 4.8 2.1 6.3 5 1 1 6 6 6 0 MYST family zinc finger domain PARP PF00644.20 PVD21135.1 - 3.4e-53 180.1 0.0 7.7e-53 179.0 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PVD21135.1 - 5.7e-49 165.7 0.7 1.5e-48 164.4 0.7 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WWE PF02825.20 PVD21135.1 - 1.4e-25 89.7 4.0 9.7e-16 58.1 0.4 2.6 2 0 0 2 2 2 2 WWE domain WGR PF05406.15 PVD21135.1 - 2.1e-25 88.6 2.6 2.1e-25 88.6 2.6 2.5 3 0 0 3 3 3 1 WGR domain RINGv PF12906.7 PVD21136.1 - 2.1e-15 56.5 8.3 4.3e-15 55.6 8.3 1.6 1 0 0 1 1 1 1 RING-variant domain WD40 PF00400.32 PVD21137.1 - 8.3e-40 134.1 37.3 9.5e-09 35.8 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21137.1 - 1.1e-09 38.4 6.3 0.024 14.9 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD21137.1 - 8.2e-06 25.0 5.9 0.073 12.0 1.5 4.0 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 PVD21137.1 - 7.1e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 PVD21137.1 - 0.00073 18.2 0.8 2.4 6.6 0.1 3.2 1 1 0 3 3 3 2 Cytochrome D1 heme domain TGBp3 PF02495.17 PVD21137.1 - 0.01 15.5 0.9 0.073 12.7 0.0 2.6 3 0 0 3 3 3 0 Triple gene block 3 PQQ_3 PF13570.6 PVD21137.1 - 0.012 16.1 0.0 0.072 13.6 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Hira PF07569.11 PVD21137.1 - 0.27 10.9 7.4 0.92 9.2 1.4 3.3 2 2 1 3 3 3 0 TUP1-like enhancer of split MMS1_N PF10433.9 PVD21138.1 - 9.6e-143 476.3 0.0 8e-119 397.4 0.0 2.8 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PVD21138.1 - 1.5e-99 333.4 0.0 5.9e-98 328.1 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 PVD21138.1 - 0.039 14.2 0.0 4.9 7.5 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain COG4 PF08318.12 PVD21139.1 - 5.7e-85 285.4 6.6 1.6e-83 280.5 6.6 2.4 1 1 0 1 1 1 1 COG4 transport protein Sec10 PF07393.11 PVD21139.1 - 4e-06 25.6 0.9 8.5e-06 24.5 0.0 2.0 2 1 0 2 2 2 1 Exocyst complex component Sec10 Seryl_tRNA_N PF02403.22 PVD21139.1 - 6.6 7.0 7.3 8.9 6.6 0.5 3.8 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.32 PVD21140.1 - 1e-19 70.4 31.8 2.2e-05 25.1 0.6 8.6 9 0 0 9 9 8 4 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 PVD21140.1 - 2.8e-08 33.6 10.7 9.9e-08 31.9 10.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD21140.1 - 1.1e-06 28.4 8.6 1.1e-06 28.4 8.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21140.1 - 4.5e-06 26.7 9.3 4.5e-06 26.7 9.3 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD21140.1 - 8.6e-06 25.5 9.5 8.6e-06 25.5 9.5 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21140.1 - 2.1e-05 24.3 9.5 2.1e-05 24.3 9.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 PVD21140.1 - 0.00015 22.4 6.1 0.00015 22.4 6.1 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_5 PF14634.6 PVD21140.1 - 0.0013 18.7 10.1 0.0013 18.7 10.1 3.1 2 1 1 3 3 3 1 zinc-RING finger domain UPF0242 PF06785.11 PVD21140.1 - 0.0013 18.8 3.1 0.0024 18.0 3.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus zf-RING_2 PF13639.6 PVD21140.1 - 0.0019 18.5 10.4 0.013 15.8 10.4 2.6 1 0 0 1 1 1 1 Ring finger domain Nup160 PF11715.8 PVD21140.1 - 0.002 16.9 0.9 3.7 6.1 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 HOOK PF05622.12 PVD21140.1 - 0.0026 16.0 1.1 0.0036 15.5 1.1 1.1 1 0 0 1 1 1 1 HOOK protein zf-RING_6 PF14835.6 PVD21140.1 - 0.003 17.4 3.7 0.003 17.4 3.7 2.3 2 0 0 2 2 1 1 zf-RING of BARD1-type protein ANAPC4_WD40 PF12894.7 PVD21140.1 - 0.0032 17.8 0.1 0.79 10.1 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 PVD21140.1 - 0.0058 16.5 9.6 0.029 14.2 9.6 2.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PI3K_P85_iSH2 PF16454.5 PVD21140.1 - 0.011 15.3 2.3 0.017 14.7 2.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain zf-Nse PF11789.8 PVD21140.1 - 0.02 14.7 5.4 0.055 13.3 5.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ran-binding PF05508.11 PVD21140.1 - 0.021 13.8 2.0 0.037 13.0 2.0 1.3 1 0 0 1 1 1 0 RanGTP-binding protein Fmp27_WPPW PF10359.9 PVD21140.1 - 0.024 13.5 2.1 0.035 13.0 2.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.9 PVD21140.1 - 0.038 14.0 3.6 0.07 13.2 3.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 PVD21140.1 - 0.076 12.3 3.8 0.13 11.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SKA1 PF07160.12 PVD21140.1 - 0.084 12.7 1.4 0.14 12.0 1.4 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF745 PF05335.13 PVD21140.1 - 0.11 12.2 0.7 0.17 11.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Cnn_1N PF07989.11 PVD21140.1 - 0.12 12.5 4.6 0.2 11.8 4.6 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 PVD21140.1 - 0.18 12.1 3.2 0.31 11.4 3.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RmuC PF02646.16 PVD21140.1 - 0.19 10.8 3.4 0.33 10.0 3.4 1.3 1 0 0 1 1 1 0 RmuC family zf-RING_10 PF16685.5 PVD21140.1 - 0.26 11.5 10.4 1.2 9.3 10.4 2.2 1 1 0 1 1 1 0 zinc RING finger of MSL2 UPF0184 PF03670.13 PVD21140.1 - 0.34 11.3 1.9 1.6 9.2 1.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) HAUS-augmin3 PF14932.6 PVD21140.1 - 0.41 10.2 4.8 0.63 9.6 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 PVD21140.1 - 1 9.4 6.1 1.7 8.7 6.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sina PF03145.16 PVD21140.1 - 1.3 8.9 19.1 0.22 11.4 3.3 3.1 2 1 1 3 3 2 0 Seven in absentia protein family SlyX PF04102.12 PVD21140.1 - 1.8 9.2 5.3 10 6.8 0.5 2.4 1 1 1 2 2 2 0 SlyX Ets PF00178.22 PVD21142.1 - 4.1e-36 123.3 0.1 5.9e-36 122.8 0.1 1.2 1 0 0 1 1 1 1 Ets-domain Ets PF00178.22 PVD21146.1 - 2.3e-36 124.1 0.1 3.3e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 PVD21147.1 - 1.4e-18 66.6 0.1 2.3e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 PVD21147.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BAALC_N PF06989.12 PVD21147.1 - 0.041 14.2 0.2 0.14 12.4 0.2 1.9 1 0 0 1 1 1 0 BAALC N-terminus PQ-loop PF04193.14 PVD21149.1 - 9.4e-31 105.4 1.0 1.1e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 PVD21149.1 - 0.0021 18.9 6.7 0.35 11.7 0.2 2.4 2 1 0 2 2 2 2 ER lumen protein retaining receptor CCCAP PF15964.5 PVD21150.1 - 0.022 13.1 0.2 0.026 12.8 0.2 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family BLOC1_2 PF10046.9 PVD21150.1 - 0.03 14.6 0.1 0.063 13.6 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PNP_UDP_1 PF01048.20 PVD21151.1 - 1.6e-45 155.2 0.0 1.5e-44 152.0 0.0 2.1 2 0 0 2 2 2 1 Phosphorylase superfamily Beta-lactamase PF00144.24 PVD21151.1 - 3.8e-23 82.2 0.2 2.8e-22 79.4 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 PVD21151.1 - 1e-06 29.1 0.1 2.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Tubulin PF00091.25 PVD21152.1 - 9.3e-55 185.9 0.0 1.7e-54 185.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD21152.1 - 1.1e-43 148.4 0.1 1.5e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PVD21152.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PVD21152.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PVD21152.1 - 0.017 14.4 0.1 0.037 13.2 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 PVD21153.1 - 1e-54 185.8 0.0 1.9e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD21153.1 - 2e-43 147.5 0.1 2.8e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PVD21153.1 - 1.9e-05 25.0 0.0 4.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PVD21153.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 PVD21153.1 - 0.035 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Glyco_hydro_16 PF00722.21 PVD21155.1 - 9.8e-20 70.8 0.5 9.8e-20 70.8 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 PVD21156.1 - 1.2e-15 57.4 3.7 1.2e-15 57.4 3.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CBM39 PF15886.5 PVD21156.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Ldl_recept_a PF00057.18 PVD21158.1 - 6.3e-08 32.7 6.4 2e-07 31.1 6.4 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A ECH_1 PF00378.20 PVD21159.1 - 0.034 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PVD21160.1 - 4.2e-36 124.5 0.0 5.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 PVD21160.1 - 1.2e-28 99.2 1.2 1.2e-28 99.2 1.2 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein ECH_2 PF16113.5 PVD21160.1 - 1.2e-20 74.4 0.0 1.8e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FERM_M PF00373.18 PVD21160.1 - 0.16 12.4 0.4 0.46 10.9 0.4 1.7 1 0 0 1 1 1 0 FERM central domain ECH_1 PF00378.20 PVD21161.1 - 2e-33 115.8 0.0 3.9e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD21161.1 - 5.8e-11 42.5 0.0 5.8e-11 42.5 0.0 2.1 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase CDT1 PF08839.11 PVD21162.1 - 1.6e-49 168.6 0.1 1.6e-49 168.6 0.1 2.7 3 0 0 3 3 3 1 DNA replication factor CDT1 like CDT1_C PF16679.5 PVD21162.1 - 9.3e-26 90.1 5.2 1.1e-25 89.8 1.7 3.1 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain HEAT PF02985.22 PVD21163.1 - 3.8e-14 51.6 3.8 0.0065 16.6 0.1 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 PVD21163.1 - 7.5e-08 32.7 0.5 0.005 17.2 0.1 3.5 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 PVD21163.1 - 5.9e-05 23.5 3.5 0.085 13.4 0.7 3.7 2 0 0 2 2 2 2 HEAT-like repeat HOOK PF05622.12 PVD21163.1 - 0.0044 15.2 1.7 0.0044 15.2 1.7 1.9 2 0 0 2 2 2 1 HOOK protein MbeD_MobD PF04899.12 PVD21163.1 - 0.0091 16.1 2.1 0.039 14.1 2.1 2.1 1 0 0 1 1 1 1 MbeD/MobD like Takusan PF04822.13 PVD21163.1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.7 3 0 0 3 3 3 0 Takusan LisH PF08513.11 PVD21163.1 - 0.09 12.8 0.8 0.2 11.6 0.8 1.7 1 0 0 1 1 1 0 LisH DUF3385 PF11865.8 PVD21163.1 - 0.12 12.2 0.1 48 3.8 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Arm PF00514.23 PVD21163.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF4140 PF13600.6 PVD21163.1 - 0.26 11.7 1.4 6.3 7.3 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 PVD21163.1 - 0.32 11.1 5.3 0.089 12.9 1.8 1.9 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 PVD21163.1 - 2.9 8.0 7.6 0.91 9.7 3.2 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 OmpH PF03938.14 PVD21163.1 - 4 7.8 8.8 10 6.4 1.4 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 PVD21163.1 - 4.3 8.0 9.1 14 6.3 3.3 3.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-H2C2_2 PF13465.6 PVD21164.1 - 1.3e-13 50.7 35.7 8.7e-08 32.3 0.7 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21164.1 - 1.3e-09 38.0 33.8 6.1e-05 23.3 3.7 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD21164.1 - 1.9e-08 33.9 35.8 1.1e-05 25.1 4.8 5.0 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD21164.1 - 0.0021 18.8 31.8 0.021 15.6 2.6 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HE PF16278.5 PVD21164.1 - 0.0052 17.2 11.4 0.03 14.8 0.3 3.8 3 1 1 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger TMA7 PF09072.10 PVD21164.1 - 0.13 13.1 1.8 0.23 12.3 0.4 2.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 Actin_micro PF17003.5 PVD21164.1 - 0.23 10.6 10.1 0.39 9.9 0.2 2.8 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2_7 PF15269.6 PVD21164.1 - 8.9 6.5 10.7 18 5.5 0.1 3.3 1 1 2 3 3 3 0 Zinc-finger zf-C2H2 PF00096.26 PVD21166.1 - 1.5e-32 110.2 90.3 5e-06 26.7 0.4 10.9 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21166.1 - 1e-28 97.5 82.5 0.00073 20.2 0.9 11.4 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21166.1 - 4.9e-26 90.0 75.5 9.4e-08 32.1 0.4 11.8 15 0 0 15 15 14 6 Zinc-finger double domain zf-met PF12874.7 PVD21166.1 - 2.8e-18 65.6 68.4 0.04 14.3 1.7 10.5 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD21166.1 - 5.5e-12 45.7 55.9 0.013 15.7 0.1 10.2 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD21166.1 - 0.00058 19.8 78.0 0.017 15.1 1.5 10.6 11 0 0 11 11 11 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD21166.1 - 0.0028 17.4 1.0 0.0028 17.4 1.0 9.3 9 0 0 9 9 8 4 zinc-finger C2H2-type LIM_bind PF01803.16 PVD21166.1 - 0.18 11.3 1.4 0.53 9.8 1.4 1.8 1 0 0 1 1 1 0 LIM-domain binding protein zf-C2H2_2 PF12756.7 PVD21166.1 - 0.44 10.9 60.2 0.3 11.4 1.7 9.6 5 4 5 10 10 10 0 C2H2 type zinc-finger (2 copies) IBD PF10416.9 PVD21166.1 - 0.68 9.9 2.7 38 4.3 0.1 3.3 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Desulfoferrod_N PF06397.12 PVD21166.1 - 0.83 9.3 14.2 4.7 6.9 0.3 4.7 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-C2HE PF16278.5 PVD21166.1 - 1.5 9.3 47.8 2.6 8.6 2.7 7.6 6 1 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger BUD22 PF09073.10 PVD21167.1 - 1.4 8.1 5.1 1.8 7.9 5.1 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 PVD21167.1 - 2.6 8.8 9.7 7.3 7.3 8.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 PVD21167.1 - 3 6.0 7.3 3.7 5.6 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 PVD21167.1 - 4.2 6.4 9.6 4.9 6.2 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-H2C2_2 PF13465.6 PVD21173.1 - 2.1e-46 154.3 71.1 2.9e-09 36.9 2.1 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 PVD21173.1 - 9.4e-32 108.4 68.4 2e-08 33.8 0.3 10.3 9 1 0 9 9 9 8 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD21173.1 - 6.1e-29 98.8 76.2 2.5e-05 24.5 2.3 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21173.1 - 5.8e-16 57.8 82.0 0.00081 20.0 1.5 11.6 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21173.1 - 2.1e-05 24.7 41.4 0.067 13.5 0.1 8.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD21173.1 - 0.0012 19.0 1.6 0.0012 19.0 1.6 6.8 4 2 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD21173.1 - 0.13 12.1 0.1 0.13 12.1 0.1 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type GAGA PF09237.11 PVD21173.1 - 0.67 9.8 19.6 4.7 7.1 0.2 6.5 2 2 4 6 6 6 0 GAGA factor zf-C2H2_9 PF16293.5 PVD21173.1 - 3.6 7.5 10.9 16 5.5 0.3 5.0 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Receptor_2B4 PF11465.8 PVD21174.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 zf-C2HC PF01530.18 PVD21174.1 - 8.2 6.7 7.7 18 5.6 0.1 3.1 4 0 0 4 4 4 0 Zinc finger, C2HC type Transglut_N PF00868.20 PVD21176.1 - 4.7e-35 120.5 0.1 1.6e-34 118.7 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 PVD21176.1 - 2.4e-23 82.3 0.4 1.7e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 PVD21176.1 - 1.4e-15 57.7 0.2 3.2e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1043 PF06295.12 PVD21177.1 - 0.028 14.4 3.2 4 7.5 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) EF-hand_6 PF13405.6 PVD21179.1 - 2.2e-07 30.2 1.4 0.022 14.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PVD21179.1 - 4.2e-07 30.3 1.9 4.2e-07 30.3 1.9 3.8 4 1 0 4 4 4 1 EF-hand domain pair Ntox8 PF15545.6 PVD21179.1 - 0.15 12.2 2.1 0.33 11.1 0.2 2.6 3 0 0 3 3 3 0 Bacterial toxin 8 EF-hand_1 PF00036.32 PVD21179.1 - 0.16 11.6 3.3 1.2 8.9 0.2 3.0 3 0 0 3 3 3 0 EF hand CAP PF00188.26 PVD21180.1 - 3.6e-18 66.6 5.8 8e-11 42.9 0.5 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Cellulase PF00150.18 PVD21180.1 - 0.00094 18.7 0.7 0.08 12.3 0.2 2.8 2 1 1 3 3 3 1 Cellulase (glycosyl hydrolase family 5) CaMKII_AD PF08332.10 PVD21180.1 - 0.029 14.5 0.3 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain MEKHLA PF08670.11 PVD21180.1 - 0.11 12.3 0.3 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 MEKHLA domain F-box_4 PF15966.5 PVD21181.1 - 1.8e-34 118.1 0.4 1.8e-34 118.1 0.4 2.1 2 0 0 2 2 2 1 F-box F-box PF00646.33 PVD21181.1 - 3.5e-07 30.0 4.6 8.3e-07 28.7 4.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PVD21181.1 - 9e-06 25.5 0.9 2.2e-05 24.3 0.9 1.6 1 0 0 1 1 1 1 F-box-like zf-TRAF_2 PF15965.5 PVD21181.1 - 0.00013 22.3 0.2 0.00013 22.3 0.2 3.8 3 1 1 4 4 4 1 TRAF-like zinc-finger PTB PF08416.13 PVD21182.1 - 3.4e-10 40.2 0.0 6.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 PVD21182.1 - 4.4e-07 29.4 0.1 8.1e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD21182.1 - 2.7e-05 23.8 0.1 5.8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD21182.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 PVD21182.1 - 0.00043 20.5 0.1 0.00093 19.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 PVD21182.1 - 0.0082 16.2 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Cdh1_DBD_1 PF18196.1 PVD21182.1 - 0.075 13.4 1.8 0.097 13.0 0.7 1.7 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 PH_13 PF16652.5 PVD21182.1 - 0.08 12.7 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain CFAP91 PF14738.6 PVD21182.1 - 0.38 10.8 4.7 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Cilia- and flagella-associated protein 91 SAM_3 PF18016.1 PVD21183.1 - 3.9e-18 65.0 0.0 5.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CAP_N PF01213.19 PVD21183.1 - 0.0041 16.7 1.3 0.0052 16.3 1.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD21183.1 - 0.16 12.0 0.3 0.2 11.7 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Ldl_recept_a PF00057.18 PVD21186.1 - 1.5e-07 31.5 4.7 3.6e-07 30.3 4.7 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Herpes_glycop PF01528.16 PVD21186.1 - 0.11 11.4 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M CytochromB561_N PF09786.9 PVD21186.1 - 1.7 7.5 10.6 3 6.7 10.6 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Spt46 PF17734.1 PVD21186.1 - 3.1 7.6 8.5 0.26 11.0 3.5 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 zf-RanBP PF00641.18 PVD21187.1 - 0.0014 17.9 3.5 0.0014 17.9 3.5 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 PVD21187.1 - 0.15 12.1 13.0 0.32 11.1 13.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-CHY PF05495.12 PVD21187.1 - 8.5 7.0 7.9 43 4.7 7.9 2.0 1 1 0 1 1 1 0 CHY zinc finger GAS PF13851.6 PVD21189.1 - 1.2e-73 246.8 28.5 1.2e-73 246.8 28.5 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 PVD21189.1 - 0.0055 16.8 7.9 0.0055 16.8 7.9 7.0 2 2 6 8 8 8 2 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 PVD21189.1 - 0.0089 16.1 9.1 0.0089 16.1 9.1 4.4 1 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flg_hook PF02120.16 PVD21189.1 - 0.011 15.6 2.6 5.1 7.1 0.0 3.5 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Virulence_fact PF13769.6 PVD21189.1 - 0.093 13.0 0.3 0.093 13.0 0.3 4.0 5 1 0 5 5 5 0 Virulence factor FoP_duplication PF13865.6 PVD21189.1 - 0.47 11.0 10.6 1.6 9.3 10.6 2.0 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4854 PF16146.5 PVD21189.1 - 1.8 8.9 6.2 12 6.3 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) COG5 PF10392.9 PVD21189.1 - 4.6 7.4 19.4 0.024 14.8 4.2 3.8 2 1 2 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 PVD21189.1 - 4.8 7.2 14.1 4.9 7.2 3.5 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 PVD21189.1 - 7.3 5.4 59.2 0.5 9.2 21.5 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein FERM_N PF09379.10 PVD21190.1 - 7.7e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 PVD21190.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD21190.1 - 0.1 13.0 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 FERM central domain Ribosomal_S17 PF00366.20 PVD21191.1 - 1.7e-07 31.2 0.6 2.5e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 RNase_PH PF01138.21 PVD21192.1 - 1.2e-22 80.9 0.0 1.8e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PVD21192.1 - 4.2e-10 39.5 0.2 1.3e-09 38.0 0.2 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 7tm_3 PF00003.22 PVD21196.1 - 3.4e-43 148.1 21.0 4.3e-43 147.8 21.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EGF_CA PF07645.15 PVD21196.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.6 2 0 0 2 2 2 0 Calcium-binding EGF domain Ank_4 PF13637.6 PVD21197.1 - 2.7e-48 161.7 18.3 1.2e-08 35.3 0.1 9.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD21197.1 - 5e-48 161.6 12.9 8.5e-16 58.3 0.1 6.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD21197.1 - 1.4e-44 149.6 17.8 7.2e-09 35.7 0.1 7.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 PVD21197.1 - 1.7e-40 135.7 28.2 3.1e-05 24.2 0.1 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 PVD21197.1 - 1.8e-36 120.0 15.6 0.00025 21.2 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat VPS9 PF02204.18 PVD21197.1 - 8.4e-18 64.5 0.0 2.8e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DAO PF01266.24 PVD21198.1 - 3.5e-41 141.9 0.0 4.4e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PVD21199.1 - 4.8e-40 138.2 0.0 5.9e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PVD21199.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PVD21199.1 - 0.14 11.2 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pkinase_Tyr PF07714.17 PVD21200.1 - 5.9e-85 284.7 0.0 9.2e-85 284.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 PVD21200.1 - 2.2e-52 178.3 0.1 8.4e-52 176.4 0.0 1.8 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase PF00069.25 PVD21200.1 - 7.2e-42 143.6 0.0 1.2e-41 142.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD21200.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD21200.1 - 0.033 13.5 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNAP PF14938.6 PVD21201.1 - 2.2e-22 79.8 12.2 3e-22 79.4 12.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 PVD21201.1 - 1.6e-07 31.0 1.1 1e-06 28.4 0.3 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 PVD21201.1 - 3.8e-06 27.1 9.7 0.0031 17.8 0.3 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD21201.1 - 2.1e-05 24.1 15.2 0.53 10.2 1.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD21201.1 - 2.6e-05 24.1 12.9 2.3 8.7 1.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD21201.1 - 0.0043 17.0 6.9 0.54 10.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD21201.1 - 0.016 15.3 22.0 1.7 9.0 0.2 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD21201.1 - 0.027 14.2 7.5 7.9 6.3 0.0 4.0 4 0 0 4 4 4 0 TPR repeat Clathrin PF00637.20 PVD21201.1 - 0.05 13.5 5.3 5.8 6.8 0.8 3.5 1 1 0 2 2 2 0 Region in Clathrin and VPS TPR_19 PF14559.6 PVD21201.1 - 0.25 11.9 12.6 0.08 13.5 1.5 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 PVD21201.1 - 0.33 11.5 3.6 1.4 9.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) MIT PF04212.18 PVD21201.1 - 0.59 10.2 16.3 2.2 8.4 0.2 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PVD21201.1 - 0.92 10.3 8.8 82 4.2 0.5 5.6 4 3 1 5 5 5 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 PVD21202.1 - 3.3e-18 66.1 0.1 5.2e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding GMC_oxred_N PF00732.19 PVD21203.1 - 2.5e-57 194.5 0.0 4.1e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HAD_2 PF13419.6 PVD21203.1 - 1.7e-35 122.7 0.1 7.4e-19 68.5 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD21203.1 - 4.9e-30 105.4 0.1 2.3e-15 57.5 0.0 4.0 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.13 PVD21203.1 - 4e-25 89.0 0.0 7.5e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Hydrolase_like PF13242.6 PVD21203.1 - 5.7e-14 51.9 0.1 1.2e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 HAD-hyrolase-like Hydrolase_3 PF08282.12 PVD21203.1 - 7e-11 42.3 0.1 0.01 15.6 0.0 4.8 5 0 0 5 5 5 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD21203.1 - 1.2e-10 42.1 0.0 9.5e-05 22.9 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Lycopene_cycl PF05834.12 PVD21203.1 - 1.4e-05 24.3 0.0 3.1e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 PVD21203.1 - 0.0008 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 PVD21203.1 - 0.0013 19.0 0.0 0.0055 16.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PVD21203.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD21203.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase S6PP PF05116.13 PVD21203.1 - 0.0085 15.6 0.1 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase FAD_binding_2 PF00890.24 PVD21203.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain EAL PF00563.20 PVD21203.1 - 0.015 14.8 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 EAL domain ApbA PF02558.16 PVD21203.1 - 0.12 12.1 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Alpha_kinase PF02816.18 PVD21204.1 - 5.9e-23 82.0 0.1 7.9e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF4573 PF15140.6 PVD21205.1 - 0.0089 15.8 29.7 0.018 14.9 26.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) DUF4777 PF16007.5 PVD21205.1 - 0.23 11.7 8.9 39 4.6 0.2 4.8 3 2 1 4 4 4 0 Domain of unknown function (DUF4777) ObR_Ig PF18589.1 PVD21205.1 - 0.27 11.7 7.2 0.24 11.8 1.8 3.0 2 1 1 3 3 3 0 Obesity receptor immunoglobulin like domain Toprim_C_rpt PF13368.6 PVD21205.1 - 8.8 6.4 15.4 6.8e+02 0.4 2.0 4.7 1 1 1 2 2 2 0 Topoisomerase C-terminal repeat BROMI PF14961.6 PVD21206.1 - 0 1314.6 14.3 0 1237.1 4.5 2.0 1 1 1 2 2 2 2 Broad-minded protein Paramyxo_ncap PF00973.19 PVD21206.1 - 0.19 10.6 0.2 0.41 9.5 0.0 1.5 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein adh_short PF00106.25 PVD21207.1 - 4e-23 81.9 0.0 5.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD21207.1 - 1.8e-19 70.2 0.0 3.2e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ferritin_2 PF13668.6 PVD21207.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain GCV_T PF01571.21 PVD21211.1 - 2.1e-68 230.5 0.0 3e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 PVD21211.1 - 1e-35 124.0 0.0 2.1e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 PVD21211.1 - 2e-18 66.5 0.6 4.5e-18 65.3 0.6 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 PVD21211.1 - 3.9e-10 39.5 0.0 9.1e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 PVD21211.1 - 0.00028 20.2 0.7 0.0012 18.2 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 PVD21211.1 - 0.00072 19.7 0.0 0.0021 18.2 0.0 1.8 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Trp_halogenase PF04820.14 PVD21211.1 - 0.0073 15.2 0.1 0.043 12.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Mss4 PF04421.13 PVD21212.1 - 5.9e-37 125.7 0.0 7.9e-37 125.3 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein Lar_restr_allev PF14354.6 PVD21212.1 - 0.091 13.2 0.1 8.4 6.9 0.0 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar TPR_2 PF07719.17 PVD21213.1 - 6.2e-06 25.9 2.1 0.042 14.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Chordopox_G2 PF05796.12 PVD21213.1 - 0.0031 17.0 0.1 0.0093 15.4 0.1 1.8 1 0 0 1 1 1 1 Chordopoxvirus protein G2 DUF3802 PF12290.8 PVD21213.1 - 0.0094 16.5 1.5 0.074 13.6 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3802) TPR_7 PF13176.6 PVD21213.1 - 0.01 15.8 0.0 5.2 7.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD21213.1 - 0.027 14.3 2.9 0.76 9.7 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD21213.1 - 0.033 14.5 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2555 PF10742.9 PVD21213.1 - 0.14 12.0 0.3 0.62 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) TPR_8 PF13181.6 PVD21213.1 - 0.21 11.9 1.5 8.5 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Mob_synth_C PF06463.13 PVD21214.1 - 0.08 12.9 3.7 1.3 9.0 1.1 2.2 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-ribbon_3 PF13248.6 PVD21214.1 - 0.14 11.6 4.8 0.8 9.2 4.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain 7tm_1 PF00001.21 PVD21216.1 - 8.4e-12 45.0 15.8 1.6e-11 44.1 15.8 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tmemb_18A PF09771.9 PVD21216.1 - 2.9 8.3 8.0 0.14 12.5 1.0 2.3 2 1 0 2 2 2 0 Transmembrane protein 188 PH_17 PF18012.1 PVD21217.1 - 9.7e-27 92.5 0.2 3.1e-26 90.9 0.1 1.9 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 PVD21217.1 - 2.1e-19 69.6 1.1 4.2e-19 68.7 1.1 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 PVD21217.1 - 2e-10 41.1 0.0 1.2e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 PVD21217.1 - 7.3e-06 25.7 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD21217.1 - 0.0016 18.8 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Acyl_transf_1 PF00698.21 PVD21218.1 - 1.7e-23 83.6 0.0 2.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PAN_1 PF00024.26 PVD21218.1 - 0.018 15.0 0.2 0.04 13.9 0.2 1.5 1 0 0 1 1 1 0 PAN domain DUF1411 PF07199.11 PVD21218.1 - 0.19 11.4 0.5 1 9.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) MCM PF00493.23 PVD21219.1 - 1.3e-98 328.6 0.0 1.9e-98 328.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PVD21219.1 - 6.5e-40 135.9 0.1 1.2e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PVD21219.1 - 1.3e-25 89.6 0.2 3e-25 88.4 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PVD21219.1 - 1.8e-17 63.8 1.7 6e-17 62.1 1.7 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PVD21219.1 - 5.9e-09 35.6 0.1 7.7e-06 25.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PVD21219.1 - 4.3e-08 33.3 0.0 1.9e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PVD21219.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PVD21219.1 - 0.042 13.5 1.0 3 7.5 0.0 2.8 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA PF00004.29 PVD21219.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2476 PF10630.9 PVD21219.1 - 6.7 6.8 12.2 1.7e+02 2.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2476) Voltage_CLC PF00654.20 PVD21220.1 - 3.5e-83 279.8 26.2 5.4e-83 279.1 26.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 PVD21220.1 - 1.1e-16 60.9 0.0 2.2e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain S1FA PF04689.13 PVD21220.1 - 0.62 10.2 5.1 0.32 11.2 2.2 2.1 1 1 1 2 2 2 0 DNA binding protein S1FA DUF1129 PF06570.11 PVD21220.1 - 1.1 8.7 3.7 1.7 8.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Phage_holin_6_1 PF09682.10 PVD21220.1 - 2.2 8.7 0.0 2.2 8.7 0.0 2.6 3 1 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Gly-zipper_YMGG PF13441.6 PVD21220.1 - 4.1 7.2 12.4 20 5.0 0.0 3.5 3 0 0 3 3 3 0 YMGG-like Gly-zipper zf-CCHC PF00098.23 PVD21221.1 - 0.00064 19.7 0.9 0.0012 18.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD21221.1 - 0.0049 16.7 1.1 0.009 15.8 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PVD21221.1 - 0.071 12.8 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn_ribbon_17 PF17120.5 PVD21221.1 - 0.52 10.0 1.5 13 5.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-CCHC PF00098.23 PVD21222.1 - 0.00045 20.2 0.9 0.00094 19.2 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD21222.1 - 0.0036 17.1 1.1 0.007 16.2 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PVD21222.1 - 0.059 13.1 0.3 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Voltage_CLC PF00654.20 PVD21223.1 - 6.1e-87 292.1 23.7 6.1e-87 292.1 23.7 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PVD21223.1 - 1.7e-11 44.4 0.0 5.6e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain Microvir_lysis PF04517.12 PVD21223.1 - 0.1 12.6 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus S1FA PF04689.13 PVD21223.1 - 0.24 11.6 5.0 0.11 12.6 1.3 2.4 1 1 1 2 2 2 0 DNA binding protein S1FA NHL PF01436.21 PVD21224.1 - 8.4e-31 104.4 5.6 4.6e-05 23.2 0.0 5.8 5 0 0 5 5 5 5 NHL repeat Filamin PF00630.19 PVD21224.1 - 6.2e-07 30.2 0.2 1.5e-06 28.9 0.2 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Prok-RING_4 PF14447.6 PVD21224.1 - 0.0011 18.8 9.2 0.0011 18.8 9.2 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD21224.1 - 0.011 16.1 11.5 0.011 16.1 11.5 2.7 2 0 0 2 2 2 0 Ring finger domain SBBP PF06739.11 PVD21224.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 Beta-propeller repeat DUF3944 PF13099.6 PVD21224.1 - 0.1 12.5 0.8 1 9.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) zf-RING_UBOX PF13445.6 PVD21224.1 - 6.8 6.8 11.6 0.85 9.7 5.2 2.9 2 1 0 2 2 2 0 RING-type zinc-finger DUF5128 PF17170.4 PVD21224.1 - 9.5 5.3 5.9 5.4 6.1 0.1 3.0 3 1 0 3 3 3 0 6-bladed beta-propeller TPR_19 PF14559.6 PVD21225.1 - 6.3e-05 23.4 2.5 2.6 8.6 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat SPO22 PF08631.10 PVD21225.1 - 0.00037 20.1 1.2 0.78 9.2 0.1 3.5 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 PVD21225.1 - 0.0028 17.7 23.3 1 9.6 0.2 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD21225.1 - 0.0029 17.4 19.2 3.3 7.7 0.2 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 PVD21225.1 - 0.0054 16.6 7.8 0.58 10.1 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD21225.1 - 0.006 16.8 14.6 4.2 7.7 0.2 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD21225.1 - 0.015 15.4 8.7 5.8 7.0 0.1 4.6 2 2 2 4 4 4 0 Putative TPR-like repeat TPR_14 PF13428.6 PVD21225.1 - 0.04 14.7 4.3 13 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 PVD21225.1 - 0.45 11.3 4.2 3.8 8.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD21225.1 - 2.5 8.7 12.5 47 4.7 0.7 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 PVD21226.1 - 2e-37 129.0 0.0 2.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21226.1 - 2.8e-22 79.2 0.0 4.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD21226.1 - 0.002 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PVD21226.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD21226.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ADH_N PF08240.12 PVD21227.1 - 5.1e-13 48.8 0.7 7.5e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PVD21227.1 - 4.4e-11 43.9 0.0 9.6e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PVD21227.1 - 0.00016 21.6 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD21227.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase PRMT5_TIM PF17285.2 PVD21228.1 - 6e-76 255.0 0.2 8e-76 254.6 0.2 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 PVD21228.1 - 5.6e-55 185.8 1.4 3.1e-38 131.3 0.0 2.2 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 PVD21228.1 - 1.2e-54 184.9 1.2 1.8e-54 184.3 1.2 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 PVD21228.1 - 0.039 14.7 0.0 0.094 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BOP1NT PF08145.12 PVD21229.1 - 1.1e-106 356.6 8.7 1.1e-106 356.6 8.7 1.5 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 PVD21229.1 - 1e-28 99.0 7.5 4.4e-10 40.0 0.5 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21229.1 - 2.1e-09 37.6 0.1 0.0046 17.2 0.1 5.8 3 3 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 PVD21229.1 - 0.26 10.7 17.2 0.41 10.0 17.2 1.4 1 0 0 1 1 1 0 SDA1 IDEAL PF08858.10 PVD21230.1 - 0.07 12.9 1.8 6.6 6.6 0.1 2.8 2 0 0 2 2 2 0 IDEAL domain DEFB136 PF17333.2 PVD21230.1 - 0.11 12.5 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Beta defensin 136 CSD PF00313.22 PVD21231.1 - 1.5e-19 69.6 0.1 6.2e-19 67.6 0.1 2.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-H2C2_2 PF13465.6 PVD21231.1 - 7.1e-16 57.8 94.8 0.0013 19.0 2.0 12.3 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21231.1 - 1.3e-12 47.4 108.0 0.025 15.0 6.0 12.9 12 0 0 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21231.1 - 3.6e-07 30.5 106.1 0.4 11.7 0.4 13.2 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD21231.1 - 0.023 14.7 0.3 0.023 14.7 0.3 8.4 8 0 0 8 8 8 0 C2H2-type zinc finger OB_RNB PF08206.11 PVD21231.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain FOXP-CC PF16159.5 PVD21231.1 - 0.47 11.1 9.6 0.081 13.6 1.5 4.1 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_7 PF15269.6 PVD21231.1 - 0.81 9.8 23.3 0.62 10.2 1.6 5.2 2 2 1 3 3 3 0 Zinc-finger zf-MYST PF17772.1 PVD21231.1 - 2.1 8.0 10.9 0.65 9.6 1.8 3.6 4 0 0 4 4 4 0 MYST family zinc finger domain FG-GAP PF01839.23 PVD21232.1 - 0.0042 17.2 1.7 0.048 13.8 0.2 2.5 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 PVD21232.1 - 0.0068 17.0 3.2 0.11 13.2 0.4 2.9 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-C2H2 PF00096.26 PVD21233.1 - 8.6e-15 54.3 70.6 0.00081 19.7 1.1 12.3 11 1 1 12 12 12 6 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD21233.1 - 1.1e-11 44.2 32.0 7.3e-05 22.4 1.6 6.9 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD21233.1 - 1.2e-11 44.4 61.1 0.037 14.9 0.2 11.8 11 0 0 11 11 11 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21233.1 - 7.2e-06 26.2 54.0 0.02 15.1 0.7 10.0 11 1 0 11 11 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD21233.1 - 1.6e-05 25.1 54.2 0.15 12.5 2.7 10.3 11 0 0 11 11 10 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD21233.1 - 3.5e-05 24.0 24.0 0.38 11.1 1.4 5.8 6 0 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 PVD21233.1 - 0.0065 16.9 0.4 0.0065 16.9 0.4 10.2 10 1 0 10 10 9 2 Zinc-finger double domain zf_C2H2_6 PF18450.1 PVD21233.1 - 0.057 13.1 0.1 0.057 13.1 0.1 4.9 5 0 0 5 5 5 0 Zinc Finger domain DUF2367 PF10164.9 PVD21233.1 - 0.058 13.9 0.4 0.44 11.1 0.4 2.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) zf_C2H2_10 PF18414.1 PVD21233.1 - 0.19 11.3 4.9 28 4.3 0.1 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger Zn-C2H2_12 PF18112.1 PVD21233.1 - 0.41 11.1 6.4 2.5 8.7 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 PVD21233.1 - 0.44 10.4 20.4 1.1 9.1 0.0 6.9 7 0 0 7 7 7 0 C2H2 type zinc-finger (1 copy) DUF2719 PF10891.8 PVD21233.1 - 0.88 9.5 3.4 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) zf-C2H2_11 PF16622.5 PVD21233.1 - 2.8 7.8 44.8 1.4 8.7 0.1 8.7 10 0 0 10 10 10 0 zinc-finger C2H2-type Motile_Sperm PF00635.26 PVD21240.1 - 3e-30 104.3 0.8 4e-30 103.9 0.8 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 PVD21240.1 - 0.03 14.5 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RMP PF14996.6 PVD21241.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.6 1 1 0 1 1 1 1 Retinal Maintenance eIF-6 PF01912.18 PVD21242.1 - 3.9e-82 274.4 0.3 5.3e-82 274.0 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family KIND PF16474.5 PVD21243.1 - 8.9e-16 58.3 0.5 9.3e-16 58.3 0.5 1.0 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain KIND PF16474.5 PVD21244.1 - 8.4e-10 38.9 0.4 2.2e-09 37.5 0.4 1.7 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain Pox_MCEL PF03291.16 PVD21245.1 - 5.9e-64 216.3 4.3 4.7e-40 137.7 0.3 2.1 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 PVD21245.1 - 7.4e-06 26.6 0.1 2.7e-05 24.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD21245.1 - 0.0064 16.3 0.1 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PVD21245.1 - 0.034 14.1 0.2 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF4503 PF14951.6 PVD21246.1 - 6.5e-38 130.2 7.9 1.1e-34 119.6 5.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4503) DUF4502 PF14950.6 PVD21246.1 - 2e-21 76.9 0.5 2e-21 76.9 0.5 2.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4502) Rep_fac-A_C PF08646.10 PVD21246.1 - 0.0019 18.0 0.1 0.0039 17.0 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain Elf1 PF05129.13 PVD21246.1 - 0.85 9.7 4.4 6.9 6.8 0.5 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TTC5_OB PF16669.5 PVD21247.1 - 1.4e-37 127.9 0.4 4.7e-37 126.2 0.9 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 PVD21247.1 - 1.3e-13 49.9 2.6 0.00023 21.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD21247.1 - 4.3e-13 48.5 3.2 0.0011 18.7 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD21247.1 - 1.8e-09 37.1 0.0 1.2e-07 31.3 0.0 3.3 3 1 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 PVD21247.1 - 2e-08 34.7 0.3 2e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD21247.1 - 2.5e-07 30.4 6.7 0.00047 20.2 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD21247.1 - 4.9e-07 30.2 0.0 2.9e-06 27.7 0.0 2.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD21247.1 - 6.3e-07 29.3 0.9 0.0036 17.6 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD21247.1 - 3.5e-05 24.0 0.2 0.036 14.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD21247.1 - 0.00024 21.7 0.1 0.028 15.2 0.0 3.5 3 2 2 5 5 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD21247.1 - 0.0005 20.2 0.0 0.036 14.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD21247.1 - 0.00095 19.7 0.0 13 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 PVD21247.1 - 0.016 14.5 0.4 0.029 13.6 0.1 1.7 2 0 0 2 2 2 0 FAT domain DBC1 PF14443.6 PVD21247.1 - 0.017 15.1 0.0 0.42 10.6 0.0 2.2 1 1 0 2 2 2 0 DBC1 ChAPs PF09295.10 PVD21247.1 - 0.035 13.1 0.0 0.078 12.0 0.0 1.5 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 PVD21247.1 - 0.081 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 PVD21247.1 - 0.083 12.1 0.1 5.7 6.1 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat GAS PF13851.6 PVD21248.1 - 0.0026 17.1 17.1 0.0043 16.4 17.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Uds1 PF15456.6 PVD21248.1 - 0.028 14.6 16.1 1.3 9.2 0.8 2.7 1 1 1 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.11 PVD21248.1 - 0.031 14.7 4.6 3.6 8.0 0.0 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 PVD21248.1 - 0.044 14.0 13.8 0.56 10.5 0.3 3.7 4 0 0 4 4 3 0 Homeobox associated leucine zipper DUF4854 PF16146.5 PVD21248.1 - 0.053 13.9 0.6 0.15 12.4 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Vps53_N PF04100.12 PVD21248.1 - 0.057 12.4 5.5 0.085 11.8 5.5 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Lebercilin PF15619.6 PVD21248.1 - 0.067 12.8 17.1 0.88 9.2 17.1 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.9 PVD21248.1 - 0.081 13.1 12.2 0.84 9.8 8.3 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 PVD21248.1 - 0.093 12.1 5.8 0.15 11.4 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 PVD21248.1 - 0.13 12.9 13.9 3.5 8.3 2.4 3.4 1 1 2 3 3 3 0 Initiation control protein YabA Leu_zip PF15294.6 PVD21248.1 - 0.21 11.1 14.2 1.8 8.0 14.0 1.9 1 1 1 2 2 2 0 Leucine zipper Golgin_A5 PF09787.9 PVD21248.1 - 0.24 10.9 13.0 0.39 10.1 13.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 PVD21248.1 - 0.27 10.3 11.3 0.47 9.5 11.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fungal_TACC PF12709.7 PVD21248.1 - 0.43 11.1 13.2 1.1 9.8 0.5 3.6 1 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins APC_N_CC PF16689.5 PVD21248.1 - 0.45 10.6 11.3 0.9 9.7 3.8 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain MAD PF05557.13 PVD21248.1 - 0.57 8.5 17.3 2.8 6.2 0.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein APG6_N PF17675.1 PVD21248.1 - 0.59 10.7 17.4 22 5.6 17.3 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region SOGA PF11365.8 PVD21248.1 - 0.6 11.3 12.7 0.27 12.4 6.3 2.8 1 1 1 2 2 2 0 Protein SOGA DUF1192 PF06698.11 PVD21248.1 - 1 9.5 7.3 16 5.6 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 PVD21248.1 - 1 9.2 16.2 0.93 9.3 2.7 3.3 1 1 2 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.6 PVD21248.1 - 1.1 9.4 16.3 1.9 8.6 0.3 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF5082 PF16888.5 PVD21248.1 - 1.1 9.6 11.4 2.1 8.6 11.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 PVD21248.1 - 1.6 8.9 22.8 3.4 7.8 12.6 3.0 1 1 2 3 3 3 0 TolA binding protein trimerisation bZIP_1 PF00170.21 PVD21248.1 - 2 8.6 13.6 1.7 8.8 1.6 3.4 1 1 2 3 3 3 0 bZIP transcription factor EMP24_GP25L PF01105.24 PVD21248.1 - 2.5 8.0 9.3 0.16 11.9 0.8 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 PVD21248.1 - 2.6 8.1 16.5 7.4 6.6 15.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 PVD21248.1 - 2.8 8.3 11.0 4.2 7.7 5.2 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) JIP_LZII PF16471.5 PVD21248.1 - 2.8 8.2 13.1 2.6 8.3 3.6 2.8 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Snapin_Pallidin PF14712.6 PVD21248.1 - 3.2 8.2 13.8 0.37 11.2 1.0 2.7 1 1 0 2 2 2 0 Snapin/Pallidin ZapB PF06005.12 PVD21248.1 - 4.4 7.8 21.2 1.8e+04 -5.1 21.2 3.3 1 1 0 1 1 0 0 Cell division protein ZapB PRKG1_interact PF15898.5 PVD21248.1 - 5.4 8.0 16.3 7.3 7.5 0.4 3.0 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_DNA_bd PF12329.8 PVD21248.1 - 5.5 7.1 18.7 0.28 11.2 2.4 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 PVD21248.1 - 6.2 7.0 18.4 37 4.5 18.8 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IFT20 PF14931.6 PVD21248.1 - 7 6.9 11.7 3.4 7.9 0.9 3.0 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 dCache_1 PF02743.18 PVD21248.1 - 7.8 6.2 8.7 11 5.8 0.8 2.4 1 1 1 2 2 2 0 Cache domain DivIVA PF05103.13 PVD21248.1 - 8.2 6.5 15.4 8.9 6.4 0.6 2.7 1 1 1 2 2 2 0 DivIVA protein TSC22 PF01166.18 PVD21248.1 - 9.4 6.6 10.5 0.7 10.2 0.6 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family CLPTM1 PF05602.12 PVD21249.1 - 7.6e-125 417.3 0.7 9e-125 417.0 0.7 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 PVD21249.1 - 0.083 12.7 6.2 0.26 11.1 0.0 4.0 4 0 0 4 4 4 0 PQ loop repeat ESSS PF10183.9 PVD21249.1 - 0.14 12.4 0.2 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TED_complement PF07678.14 PVD21250.1 - 2.1e-52 178.1 0.2 3.1e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 PVD21250.1 - 8.3e-18 64.9 0.4 2.3e-17 63.5 0.4 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 PVD21250.1 - 1.1e-16 61.5 0.2 7.3e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 PVD21250.1 - 5.4e-13 49.2 0.0 3.7e-11 43.3 0.0 3.2 3 0 0 3 3 3 1 MG2 domain A2M PF00207.22 PVD21250.1 - 8e-13 48.1 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG3 PF17791.1 PVD21250.1 - 3.7e-05 23.9 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 Ldl_recept_a PF00057.18 PVD21250.1 - 0.043 14.0 8.3 0.085 13.1 8.3 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A TED_complement PF07678.14 PVD21251.1 - 1.2e-54 185.5 0.3 1.6e-54 185.0 0.3 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 PVD21251.1 - 5.7e-20 71.8 0.1 3.6e-19 69.3 0.0 2.5 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 PVD21251.1 - 1.3e-18 67.7 0.4 3e-17 63.3 0.1 3.0 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD21251.1 - 1.1e-14 54.0 0.0 7.6e-14 51.3 0.0 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG2 PF01835.19 PVD21251.1 - 3.4e-13 49.9 0.0 3.9e-09 36.8 0.0 3.1 2 0 0 2 2 2 2 MG2 domain Ldl_recept_a PF00057.18 PVD21251.1 - 0.17 12.1 8.1 0.31 11.3 8.1 1.4 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A AA_permease_2 PF13520.6 PVD21252.1 - 1.1e-42 146.3 29.5 1.5e-42 146.0 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD21252.1 - 1.1e-16 60.5 30.0 1.4e-16 60.1 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease Arrestin_N PF00339.29 PVD21253.1 - 5.6e-31 107.6 0.0 9.8e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD21253.1 - 0.00012 22.6 0.0 0.00088 19.7 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 PVD21253.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like 5_nucleotid_C PF02872.18 PVD21254.1 - 2e-39 135.4 0.0 3.3e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PVD21254.1 - 3.4e-09 37.5 0.6 5.1e-09 36.9 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TTRAP PF14203.6 PVD21254.1 - 0.22 11.5 0.9 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Ribosomal_L13e PF01294.18 PVD21255.1 - 6.6e-74 247.6 9.1 8.5e-74 247.3 9.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Neur_chan_LBD PF02931.23 PVD21256.1 - 1.5e-33 116.1 8.5 3.4e-31 108.4 8.5 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21256.1 - 5.7e-06 26.6 3.0 5.7e-06 26.6 3.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Sulfotransfer_3 PF13469.6 PVD21257.1 - 4.4e-08 33.8 0.1 8.6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD21257.1 - 1.4e-05 24.7 0.1 2.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain 5_nucleotid_C PF02872.18 PVD21258.1 - 1.2e-39 136.1 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PVD21258.1 - 1.9e-09 38.3 0.6 2.9e-09 37.7 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TTRAP PF14203.6 PVD21258.1 - 0.22 11.6 0.9 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Ribosomal_L13e PF01294.18 PVD21259.1 - 6.6e-74 247.6 9.1 8.5e-74 247.3 9.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Neur_chan_LBD PF02931.23 PVD21260.1 - 2.6e-10 40.1 0.3 1.5e-06 27.8 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21261.1 - 6.9e-14 52.5 0.1 6.9e-14 52.5 0.1 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Sulfotransfer_3 PF13469.6 PVD21262.1 - 1.8e-16 61.2 0.1 5.3e-16 59.7 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD21262.1 - 3.2e-10 40.0 0.4 7.3e-10 38.8 0.4 1.6 1 1 0 1 1 1 1 Sulfotransferase domain 7tm_1 PF00001.21 PVD21263.1 - 1.4e-17 63.9 11.5 1.9e-17 63.5 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD21263.1 - 0.016 15.0 6.9 0.026 14.3 6.9 1.3 1 1 0 1 1 1 0 Olfactory receptor YniB PF14002.6 PVD21266.1 - 0.013 15.3 1.8 0.014 15.2 0.7 1.5 1 1 0 1 1 1 0 YniB-like protein 7TM_GPCR_Srw PF10324.9 PVD21266.1 - 0.061 12.6 2.7 0.069 12.4 2.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Nic96 PF04097.14 PVD21267.1 - 1.6e-183 611.6 0.0 2e-183 611.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ANAPC3 PF12895.7 PVD21267.1 - 0.027 14.7 1.7 0.94 9.7 0.6 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2806 PF10987.8 PVD21267.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) TPR_19 PF14559.6 PVD21267.1 - 0.069 13.7 0.2 19 5.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 PVD21267.1 - 0.11 12.8 2.0 19 5.8 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Dus PF01207.17 PVD21268.1 - 1e-46 159.5 0.3 5.6e-46 157.1 0.3 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 PVD21268.1 - 2.3e-05 25.0 0.1 6.7e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif His_biosynth PF00977.21 PVD21268.1 - 0.099 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DND1_DSRM PF14709.7 PVD21268.1 - 0.22 11.8 1.1 0.67 10.3 1.1 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 PVD21268.1 - 2.4 8.4 8.7 0.15 12.2 0.3 2.6 2 1 1 3 3 3 0 Double-stranded RNA binding domain 2 Pkinase PF00069.25 PVD21269.1 - 6.3e-27 94.6 0.0 8.1e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21269.1 - 8.1e-15 54.8 0.0 9.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD21269.1 - 3.4e-10 39.3 0.1 4.3e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 PVD21269.1 - 0.04 12.9 0.1 0.064 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 PVD21269.1 - 0.057 13.3 0.2 0.14 12.1 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD21269.1 - 0.14 11.4 0.3 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_1 PF00036.32 PVD21270.1 - 8e-16 56.3 2.0 0.00012 21.4 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 PVD21270.1 - 1.4e-13 49.6 2.8 0.00091 19.0 0.0 4.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 PVD21270.1 - 2.6e-13 50.2 4.0 1.2e-06 28.9 1.1 3.1 2 1 0 3 3 3 3 EF-hand domain pair Acyltransferase PF01553.21 PVD21270.1 - 8.7e-13 48.0 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 PVD21270.1 - 5.1e-09 35.8 1.0 0.0019 18.0 0.1 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 PVD21270.1 - 3.5e-06 27.2 0.0 0.0069 16.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD21270.1 - 0.00044 19.6 1.1 0.089 12.3 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 PVD21270.1 - 0.059 13.3 0.2 3.3 7.7 0.0 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 PVD21270.1 - 0.095 12.7 0.2 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 PVD21270.1 - 0.11 12.9 1.8 1.6 9.1 0.2 2.8 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Methyltransf_25 PF13649.6 PVD21271.1 - 5.1e-30 104.0 0.0 7.4e-14 52.2 0.0 3.3 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_11 PF08241.12 PVD21271.1 - 5.5e-27 94.2 0.0 1.7e-12 47.8 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 PVD21271.1 - 4.7e-23 81.8 0.0 2.4e-17 63.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PVD21271.1 - 9.7e-21 74.2 0.2 2.3e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PVD21271.1 - 2.6e-17 63.4 0.1 6.7e-08 33.2 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.18 PVD21271.1 - 7.7e-17 61.4 0.0 9e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PVD21271.1 - 4.7e-10 39.2 0.2 1.1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 PVD21271.1 - 2.4e-09 36.8 0.0 0.00012 21.4 0.0 2.6 1 1 1 2 2 2 2 O-methyltransferase domain CheR PF01739.18 PVD21271.1 - 1.5e-07 31.1 0.0 0.0019 17.7 0.1 2.4 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.12 PVD21271.1 - 3.1e-07 30.2 0.3 1.9e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 PVD21271.1 - 5.9e-07 29.3 0.0 2.8e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) DOT1 PF08123.13 PVD21271.1 - 2e-05 24.3 0.2 0.0099 15.4 0.0 2.4 1 1 1 2 2 2 2 Histone methylation protein DOT1 PCMT PF01135.19 PVD21271.1 - 0.00041 20.2 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 PVD21271.1 - 0.00091 18.7 0.0 0.15 11.4 0.0 2.4 2 1 0 2 2 2 1 Tellurite resistance protein TehB Bin3 PF06859.12 PVD21271.1 - 0.011 16.3 0.3 1.2 9.8 0.0 2.9 2 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PMT2_N PF17987.1 PVD21271.1 - 0.031 14.5 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Ku_PK_bind PF08785.11 PVD21271.1 - 0.14 12.3 1.1 0.24 11.5 0.2 2.0 2 1 0 2 2 1 0 Ku C terminal domain like GCV_H PF01597.19 PVD21272.1 - 7.9e-25 87.1 0.1 1.3e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein GCV_H PF01597.19 PVD21273.1 - 1.2e-25 89.7 0.2 1.4e-25 89.5 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein F-box-like PF12937.7 PVD21274.1 - 1.1e-10 41.2 1.5 1.1e-10 41.2 1.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD21274.1 - 2.1e-08 33.8 0.2 3.5e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 F-box domain DUF3506 PF12014.8 PVD21274.1 - 3.8e-06 27.0 0.2 0.0015 18.6 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box_4 PF15966.5 PVD21274.1 - 7.6e-06 25.8 0.1 1.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 F-box Thi4 PF01946.17 PVD21276.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Alpha_kinase PF02816.18 PVD21277.1 - 1e-36 126.8 0.0 2.1e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family Plasmodium_HRP PF05403.11 PVD21278.1 - 2.1e-08 34.2 16.9 7.8e-05 22.6 1.1 2.8 4 0 0 4 4 4 2 Plasmodium histidine-rich protein (HRPII/III) DUF1582 PF07621.11 PVD21278.1 - 0.0061 16.5 9.6 1.6 8.7 0.0 4.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1582) Syja_N PF02383.18 PVD21279.1 - 1.2e-94 317.3 3.6 1.5e-94 316.9 3.6 1.1 1 0 0 1 1 1 1 SacI homology domain YrhC PF14143.6 PVD21279.1 - 0.027 14.6 0.5 0.062 13.4 0.5 1.5 1 0 0 1 1 1 0 YrhC-like protein RseC_MucC PF04246.12 PVD21279.1 - 1 9.3 3.5 0.97 9.4 1.2 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TM231 PF10149.9 PVD21280.1 - 3.4e-90 302.4 0.1 3.8e-90 302.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Ras PF00071.22 PVD21281.1 - 4e-16 59.0 0.2 5.7e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 PVD21281.1 - 0.0065 16.4 0.1 0.0093 15.9 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PVD21281.1 - 0.032 13.8 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B CENP-M PF11111.8 PVD21281.1 - 0.16 11.1 0.3 0.4 9.9 0.1 1.7 2 0 0 2 2 2 0 Centromere protein M (CENP-M) Roc PF08477.13 PVD21282.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_S8 PF00082.22 PVD21283.1 - 1.4e-41 142.7 0.0 2.3e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF4350 PF14258.6 PVD21283.1 - 0.023 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) ABC_transp_aux PF09822.9 PVD21283.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Ank_4 PF13637.6 PVD21284.1 - 6.3e-13 49.0 0.1 6e-08 33.1 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD21284.1 - 4.9e-10 39.8 0.2 7.6e-08 32.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD21284.1 - 5e-08 33.0 7.5 0.0097 16.3 0.0 4.8 4 2 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PVD21284.1 - 7.2e-08 32.5 0.3 8.4e-06 26.0 0.1 3.4 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD21284.1 - 2.3e-06 27.5 1.9 0.017 15.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat SOCS_box PF07525.16 PVD21284.1 - 8.1e-05 22.9 5.1 0.00019 21.7 5.1 1.6 1 0 0 1 1 1 1 SOCS box SBF2 PF12335.8 PVD21285.1 - 2.1e-06 27.5 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin protein DUF3754 PF12576.8 PVD21286.1 - 5.3e-18 65.3 0.5 1.4e-17 63.9 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3754) DUF3736 PF12540.8 PVD21287.1 - 7.5e-17 61.7 2.2 7.5e-17 61.7 2.2 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF3736) MVP_shoulder PF11978.8 PVD21287.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shoulder domain YhfH PF14149.6 PVD21287.1 - 0.61 10.1 4.0 13 5.8 0.8 3.3 2 0 0 2 2 2 0 YhfH-like protein Roc PF08477.13 PVD21288.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD21288.1 - 0.13 12.6 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain PAP_assoc PF03828.19 PVD21290.1 - 5.6e-19 68.1 0.0 1.4e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PVD21290.1 - 3.3e-12 46.5 0.1 6.3e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PVD21290.1 - 0.0076 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Arrestin_N PF00339.29 PVD21291.1 - 1.9e-35 122.0 0.1 9.9e-35 119.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD21291.1 - 4.5e-20 72.5 0.0 5.9e-15 55.9 0.1 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD21291.1 - 0.00076 18.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Rgp1 DUF3452 PF11934.8 PVD21292.1 - 1.6e-48 163.8 1.0 1.6e-48 163.8 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) A_thal_3526 PF09713.10 PVD21292.1 - 0.014 15.6 0.3 0.028 14.6 0.3 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) TFIIB PF00382.19 PVD21292.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat RB_A PF01858.17 PVD21293.1 - 1.8e-75 253.1 0.7 1.1e-74 250.5 0.1 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 PVD21293.1 - 8.5e-52 174.7 0.0 1.8e-51 173.7 0.0 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Rb_C PF08934.10 PVD21293.1 - 0.02 14.7 0.9 0.047 13.5 0.9 1.6 1 0 0 1 1 1 0 Rb C-terminal domain 7tm_1 PF00001.21 PVD21294.1 - 3.3e-14 52.8 17.8 8.6e-14 51.5 17.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD21294.1 - 6.7e-13 48.6 16.2 9.3e-13 48.1 16.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Sulf_transp PF04143.14 PVD21294.1 - 0.0097 15.5 1.9 0.087 12.4 0.4 2.1 2 0 0 2 2 2 1 Sulphur transport DUF2116 PF09889.9 PVD21294.1 - 0.034 14.1 0.9 8.2 6.5 0.0 3.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) STE3 PF02076.15 PVD21294.1 - 0.036 13.3 13.2 0.0099 15.1 6.3 2.5 2 1 0 2 2 2 0 Pheromone A receptor UPF0542 PF15086.6 PVD21294.1 - 0.18 11.7 2.2 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 DUF1772 PF08592.11 PVD21294.1 - 1.3 9.3 7.7 0.66 10.3 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) DUF4708 PF15813.5 PVD21295.1 - 7.8e-20 71.2 0.3 5.8e-18 65.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4708) Ish1 PF10281.9 PVD21295.1 - 0.02 15.2 1.1 0.046 14.0 0.1 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein HEAT PF02985.22 PVD21296.1 - 2.6e-18 64.5 1.5 0.063 13.6 0.0 8.6 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 PVD21296.1 - 1.5e-11 44.6 2.4 0.19 11.7 0.0 6.9 4 1 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PVD21296.1 - 2.1e-10 40.8 3.1 0.24 12.0 0.0 8.6 10 0 0 10 10 9 2 HEAT-like repeat HEAT_2 PF13646.6 PVD21296.1 - 4e-08 33.5 0.1 0.31 11.5 0.0 8.0 6 1 3 9 9 9 1 HEAT repeats Vac14_Fab1_bd PF12755.7 PVD21296.1 - 1.4e-05 25.6 0.5 3.1 8.4 0.0 7.1 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PVD21296.1 - 4.4e-05 23.1 0.7 6.1 6.3 0.1 5.1 4 1 1 5 5 5 2 CLASP N terminal Nipped-B_C PF12830.7 PVD21296.1 - 0.00012 22.1 0.2 0.0039 17.2 0.0 3.5 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 PVD21296.1 - 0.0026 18.0 0.0 14 6.1 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion APP_E2 PF12925.7 PVD21296.1 - 0.0091 15.7 0.1 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 E2 domain of amyloid precursor protein DUF4042 PF13251.6 PVD21296.1 - 0.017 14.8 3.1 0.71 9.5 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) IFRD PF05004.13 PVD21296.1 - 0.027 13.6 2.5 0.6 9.2 0.0 3.9 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) RhoGAP PF00620.27 PVD21296.1 - 0.028 14.3 0.1 0.028 14.3 0.1 3.1 4 0 0 4 4 4 0 RhoGAP domain DUF1981 PF09324.10 PVD21296.1 - 1.4 8.8 8.9 12 5.8 0.2 4.6 5 0 0 5 5 4 0 Domain of unknown function (DUF1981) UME PF08064.13 PVD21296.1 - 2.3 8.2 16.0 5 7.1 0.0 6.2 9 0 0 9 9 8 0 UME (NUC010) domain EF-hand_6 PF13405.6 PVD21297.1 - 1.7e-05 24.3 0.7 0.048 13.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD21297.1 - 7.7e-05 22.0 2.4 0.066 12.8 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD21297.1 - 8.4e-05 22.3 0.9 0.0051 16.6 0.4 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PVD21297.1 - 0.00037 20.9 0.1 0.00092 19.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD21297.1 - 0.029 13.9 0.5 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 EF hand NAM-associated PF14303.6 PVD21297.1 - 0.084 13.6 8.9 0.13 12.9 8.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MCM3AP_GANP PF16769.5 PVD21297.1 - 4 5.6 4.8 5.7 5.1 4.8 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Peptidase_M14 PF00246.24 PVD21298.1 - 2.2e-72 244.3 0.0 2.9e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 PVD21298.1 - 4.5e-12 46.2 1.5 6.9e-12 45.6 0.4 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 PVD21299.1 - 4.1e-59 200.8 0.0 5e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase tRNA-synt_1d PF00750.19 PVD21300.1 - 9.8e-88 294.4 1.4 1.9e-87 293.5 1.4 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) VIT PF08487.10 PVD21300.1 - 1.5e-40 137.8 0.1 1.9e-28 98.9 0.0 2.7 2 0 0 2 2 2 2 Vault protein inter-alpha-trypsin domain VWA PF00092.28 PVD21300.1 - 9.2e-37 127.0 2.6 4.8e-19 69.3 0.5 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD21300.1 - 3.8e-34 117.9 0.0 2e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD21300.1 - 3.7e-26 91.9 0.5 2.8e-13 50.4 0.0 3.5 3 0 0 3 3 3 2 von Willebrand factor type A domain DALR_1 PF05746.15 PVD21300.1 - 6.3e-23 81.2 0.0 1.6e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain HYR PF02494.16 PVD21300.1 - 1.1e-15 57.8 1.7 1.9e-13 50.6 1.7 3.1 2 0 0 2 2 2 1 HYR domain Ephrin_rec_like PF07699.13 PVD21300.1 - 2e-13 49.9 22.4 5.7e-09 35.6 5.5 2.8 2 0 0 2 2 2 2 Putative ephrin-receptor like FXa_inhibition PF14670.6 PVD21300.1 - 1.1e-06 28.8 7.0 1.1e-06 28.8 7.0 3.9 3 1 0 3 3 2 1 Coagulation Factor Xa inhibitory site VWA_CoxE PF05762.14 PVD21300.1 - 4.7e-06 26.2 0.0 0.071 12.5 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein EGF_3 PF12947.7 PVD21300.1 - 3e-05 24.1 7.1 3e-05 24.1 7.1 3.3 3 0 0 3 3 2 1 EGF domain vWA-TerF-like PF10138.9 PVD21300.1 - 4.5e-05 23.6 0.7 0.062 13.4 0.1 2.7 2 0 0 2 2 2 2 vWA found in TerF C terminus DUF4806 PF16064.5 PVD21300.1 - 0.00013 22.1 0.0 0.00058 20.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) CobT_C PF11775.8 PVD21300.1 - 0.00097 18.8 0.1 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain Ldl_recept_b PF00058.17 PVD21300.1 - 0.0031 18.0 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 PVD21300.1 - 0.012 15.5 20.2 0.074 13.0 1.0 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF PF00008.27 PVD21300.1 - 0.022 15.1 15.6 0.24 11.8 3.7 2.8 2 0 0 2 2 2 0 EGF-like domain DUF2201 PF09967.9 PVD21300.1 - 0.043 14.0 0.3 10 6.3 0.0 2.9 3 0 0 3 3 2 0 VWA-like domain (DUF2201) Peptidase_S49_N PF08496.10 PVD21300.1 - 0.077 13.1 0.5 16 5.6 0.0 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Spc42p PF11544.8 PVD21300.1 - 0.83 9.7 4.6 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Spindle pole body component Spc42p APC_N_CC PF16689.5 PVD21300.1 - 2.2 8.4 6.1 23 5.1 0.5 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain EGF_MSP1_1 PF12946.7 PVD21300.1 - 6.4 6.9 8.5 7.2 6.7 6.4 2.4 2 0 0 2 2 1 0 MSP1 EGF domain 1 Ldl_recept_b PF00058.17 PVD21301.1 - 4.1e-07 30.4 0.2 0.03 14.8 0.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD21301.1 - 9.6e-07 29.0 9.0 1.6e-06 28.3 9.0 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 PVD21301.1 - 0.00052 19.7 0.2 0.09 12.3 0.0 2.2 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region EGF PF00008.27 PVD21301.1 - 0.28 11.5 9.4 0.084 13.2 5.8 2.1 2 0 0 2 2 2 0 EGF-like domain Ldl_recept_b PF00058.17 PVD21302.1 - 7e-12 45.6 2.6 3e-09 37.2 0.1 2.6 2 1 0 2 2 2 2 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 PVD21302.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Ig_3 PF13927.6 PVD21303.1 - 0.024 15.2 1.0 0.11 13.1 0.2 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Rax2 PF12768.7 PVD21303.1 - 0.057 12.9 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SNF PF00209.18 PVD21304.1 - 1.6e-18 66.8 0.2 1.9e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PRONE PF03759.13 PVD21304.1 - 0.25 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) DUF3291 PF11695.8 PVD21305.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Na_Pi_cotrans PF02690.15 PVD21306.1 - 0.00046 20.3 16.0 0.017 15.2 7.8 2.6 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF543 PF04418.12 PVD21306.1 - 0.73 9.9 8.3 0.49 10.4 3.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Phospholip_A2_3 PF09056.11 PVD21307.1 - 1.2e-17 64.6 10.3 1.6e-08 35.1 1.7 3.2 2 1 1 3 3 3 3 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 PVD21307.1 - 3.1e-06 27.2 12.0 0.0016 18.4 3.6 3.1 3 0 0 3 3 3 2 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF1353 PF07087.11 PVD21307.1 - 8.1e-05 22.3 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1353) Phospholip_A2_1 PF00068.19 PVD21307.1 - 0.12 12.9 9.8 1 9.9 0.5 2.4 2 0 0 2 2 2 0 Phospholipase A2 DUF1660 PF07874.11 PVD21307.1 - 0.53 10.8 4.8 8.3 7.0 0.3 2.5 2 0 0 2 2 2 0 Prophage protein (DUF1660) DUF2576 PF10845.8 PVD21307.1 - 2.5 7.8 7.5 6.2 6.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) HMMR_C PF15908.5 PVD21308.1 - 1.6e-15 57.7 10.0 1.6e-15 57.7 10.0 4.2 2 1 2 4 4 4 1 Hyaluronan mediated motility receptor C-terminal Phospholip_A2_3 PF09056.11 PVD21309.1 - 1.4e-11 45.0 1.3 2e-11 44.5 1.3 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 PVD21309.1 - 1.9e-06 27.9 2.4 2.4e-06 27.6 2.4 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 PVD21310.1 - 1.2e-10 42.0 1.6 1.8e-10 41.4 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 PVD21310.1 - 1.1e-05 25.5 2.5 1.4e-05 25.1 2.5 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 PVD21315.1 - 1.5e-10 41.6 1.9 2.3e-10 41.1 1.9 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 PVD21315.1 - 5.9e-06 26.3 2.3 7.4e-06 26.0 2.3 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) CUB PF00431.20 PVD21317.1 - 2.5e-42 143.7 3.9 1.3e-17 64.1 0.1 4.2 4 0 0 4 4 4 4 CUB domain Lectin_C PF00059.21 PVD21317.1 - 1.5e-09 38.5 0.6 5.5e-09 36.7 0.2 2.2 2 0 0 2 2 2 1 Lectin C-type domain CUB_2 PF02408.20 PVD21317.1 - 0.11 12.2 4.2 20 4.9 0.0 4.0 5 0 0 5 5 5 0 CUB-like domain CUB PF00431.20 PVD21318.1 - 2.9e-09 37.3 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 2 CUB domain EGF PF00008.27 PVD21318.1 - 1.1e-07 32.0 31.3 3.8e-05 23.9 5.6 3.9 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 PVD21318.1 - 0.038 14.4 36.0 0.12 12.8 3.0 3.9 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 PVD21318.1 - 0.98 10.2 36.5 0.13 13.0 5.9 4.6 4 0 0 4 4 4 0 Human growth factor-like EGF Cylicin_N PF15241.6 PVD21319.1 - 2 8.6 9.7 2.1 8.5 5.2 2.8 3 0 0 3 3 3 0 Cylicin N-terminus Ldl_recept_a PF00057.18 PVD21320.1 - 8e-12 45.2 36.3 1.7e-06 28.1 6.3 5.3 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A DUF4083 PF13314.6 PVD21320.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Guanylate_cyc PF00211.20 PVD21321.1 - 1.4e-43 148.7 0.1 3.5e-43 147.4 0.1 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 PVD21321.1 - 7.8e-06 26.4 0.3 0.075 13.6 0.0 2.5 1 1 1 2 2 2 2 Domain of Unknown Function (DUF1053) DUF4689 PF15755.5 PVD21321.1 - 2.2 7.8 3.9 4.1 6.9 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Guanylate_cyc PF00211.20 PVD21322.1 - 7.5e-45 152.8 0.0 1.3e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 PVD21322.1 - 3.6e-23 82.4 6.3 5.5e-23 81.8 6.3 1.3 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region ABC2_membrane_5 PF13346.6 PVD21322.1 - 1.5 8.3 12.4 1.6 8.2 11.6 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein HVSL PF09749.9 PVD21323.1 - 7.9e-33 113.9 0.2 2.5e-32 112.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-C2H2 PF00096.26 PVD21323.1 - 6.9e-17 60.9 82.0 0.00013 22.2 0.9 9.8 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21323.1 - 4.6e-12 45.7 78.5 0.027 15.3 0.8 10.4 10 0 0 10 10 9 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD21323.1 - 1.1e-09 37.9 8.3 1.5e-08 34.2 1.5 7.2 7 0 0 7 7 7 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD21323.1 - 2.1e-05 24.8 10.3 0.00023 21.4 2.3 10.5 12 0 0 12 12 10 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD21323.1 - 0.00034 20.5 1.6 0.00034 20.5 1.6 7.6 8 0 0 8 8 7 3 C2H2-type zinc finger T2SSM_b PF10741.9 PVD21323.1 - 0.16 11.8 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b zf-C2H2_7 PF15269.6 PVD21323.1 - 0.31 11.1 14.8 0.76 9.9 0.4 4.1 3 0 0 3 3 3 0 Zinc-finger GAGA PF09237.11 PVD21323.1 - 1.2 9.0 10.4 4.8 7.1 1.2 4.3 4 0 0 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.7 PVD21323.1 - 2.4 8.6 42.6 2.7 8.4 0.9 7.0 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 PVD21323.1 - 3 8.2 43.1 0.047 14.0 3.3 5.9 4 1 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 PVD21323.1 - 4.8 7.7 11.6 1.1 9.8 0.1 4.6 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 PVD21323.1 - 6.8 6.4 13.3 11 5.7 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 PVD21323.1 - 6.9 7.1 33.9 3.9 7.9 0.2 6.9 7 1 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Fanconi_A_N PF15865.5 PVD21324.1 - 3.5e-31 108.9 14.7 1.3e-23 83.9 0.3 4.7 3 2 2 5 5 5 3 Fanconi anaemia group A protein N terminus DUF3272 PF11676.8 PVD21324.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) 7tm_1 PF00001.21 PVD21325.1 - 6.1e-16 58.5 0.2 8.4e-16 58.1 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ctr PF04145.15 PVD21325.1 - 0.018 15.6 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF4834 PF16118.5 PVD21325.1 - 0.31 12.0 1.1 0.46 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ISPD_C PF18706.1 PVD21326.1 - 0.036 13.7 0.2 0.063 12.9 0.1 1.5 1 1 1 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Endonuc-BglII PF09195.11 PVD21326.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BglII Cys_rich_FGFR PF00839.17 PVD21327.1 - 4.2e-145 472.0 117.9 1e-13 51.2 1.3 16.6 14 2 1 15 15 15 15 Cysteine rich repeat UPF0029 PF01205.19 PVD21327.1 - 5.1e-33 113.6 0.1 3.8e-32 110.7 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 PVD21327.1 - 8.3e-17 61.5 2.1 5.5e-16 58.9 0.0 3.5 3 0 0 3 3 3 1 RWD domain Flavin_Reduct PF01613.18 PVD21327.1 - 0.019 15.0 0.0 0.08 13.0 0.0 2.1 2 0 0 2 2 2 0 Flavin reductase like domain YmgD PF16456.5 PVD21327.1 - 8.9 6.5 7.7 2.1 8.5 0.1 3.5 4 0 0 4 4 4 0 YmgD protein Ion_trans PF00520.31 PVD21328.1 - 1.4e-18 67.0 3.7 2e-18 66.5 3.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 PVD21328.1 - 4.9e-16 58.6 0.0 8.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD21328.1 - 2.7 8.0 6.2 0.48 10.4 2.3 1.8 2 0 0 2 2 2 0 Ion channel FeS_assembly_P PF01883.19 PVD21330.1 - 1e-18 67.3 0.8 1.1e-18 67.1 0.1 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein SEP PF08059.13 PVD21330.1 - 0.063 13.9 0.3 0.12 13.0 0.3 1.4 1 0 0 1 1 1 0 SEP domain 7tm_1 PF00001.21 PVD21331.1 - 7.9e-09 35.2 17.5 1.2e-08 34.6 17.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD21331.1 - 1.2e-05 25.1 12.9 2e-05 24.4 12.9 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5554 PF17709.1 PVD21331.1 - 0.064 13.4 0.9 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5554) CUB PF00431.20 PVD21332.1 - 0.019 15.3 0.3 0.025 14.9 0.3 1.4 1 0 0 1 1 1 0 CUB domain TMEM117 PF15113.6 PVD21332.1 - 0.19 10.6 0.3 0.25 10.3 0.3 1.1 1 0 0 1 1 1 0 TMEM117 protein family CUB PF00431.20 PVD21333.1 - 4.3e-22 78.5 0.0 7.1e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 CUB domain Tyrosinase PF00264.20 PVD21335.1 - 6.3e-34 118.2 9.7 2.5e-15 57.4 0.9 3.6 3 1 0 4 4 4 3 Common central domain of tyrosinase AAA_12 PF13087.6 PVD21336.1 - 2.3e-07 30.6 0.1 4.6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF1043 PF06295.12 PVD21336.1 - 0.077 13.0 1.2 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) AAA_11 PF13086.6 PVD21337.1 - 6.5e-12 45.8 0.1 9e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD21337.1 - 1.8e-06 28.4 0.0 3.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD21337.1 - 8.7e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD21337.1 - 9.9e-05 21.9 0.1 0.0053 16.2 0.1 2.3 1 1 1 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 PVD21337.1 - 0.00049 19.4 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PVD21337.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 PVD21337.1 - 0.0048 16.5 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 PVD21337.1 - 0.015 15.6 0.1 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PVD21337.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD21337.1 - 0.039 14.4 0.9 0.23 11.9 0.4 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD21337.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 PVD21337.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase V_ATPase_I PF01496.19 PVD21338.1 - 0.0085 14.1 2.5 0.009 14.0 2.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Toluene_X PF03349.16 PVD21338.1 - 0.28 9.7 0.2 0.36 9.3 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Nop14 PF04147.12 PVD21338.1 - 2.1 6.5 29.0 2.8 6.0 29.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.6 PVD21339.1 - 0.086 13.7 0.6 0.37 11.7 0.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21339.1 - 0.094 13.2 0.4 0.33 11.5 0.4 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type AAA_12 PF13087.6 PVD21340.1 - 1.7e-31 109.4 2.1 1.8e-25 89.7 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 PVD21340.1 - 3e-13 50.2 2.8 5.4e-12 46.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD21340.1 - 8e-07 29.5 0.0 2.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD21340.1 - 2.2e-05 24.3 0.0 5.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD21340.1 - 3e-05 23.6 0.1 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 PVD21340.1 - 0.00024 20.4 0.6 0.0033 16.7 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PVD21340.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 PVD21340.1 - 0.0022 17.8 0.8 0.026 14.3 0.1 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 PVD21340.1 - 0.016 15.5 0.1 0.079 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PVD21340.1 - 0.042 13.8 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD21340.1 - 0.058 13.8 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD21340.1 - 0.088 13.2 0.5 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF5136 PF17199.4 PVD21340.1 - 0.15 11.8 0.3 0.36 10.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) DUF4851 PF16143.5 PVD21341.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) AAA_12 PF13087.6 PVD21342.1 - 1.1e-33 116.6 0.1 1.5e-32 112.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Meis_PKNOX_N PF16493.5 PVD21342.1 - 0.079 13.3 1.0 0.26 11.7 1.0 1.9 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 AAA_12 PF13087.6 PVD21343.1 - 3e-35 121.7 1.7 7.8e-33 113.8 0.5 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PVD21343.1 - 1.4e-33 116.8 3.9 3.5e-27 95.8 0.8 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PVD21343.1 - 1.5e-10 41.5 0.2 2.6e-07 31.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD21343.1 - 2.5e-08 33.9 0.2 7.2e-05 22.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 PVD21343.1 - 1.1e-06 28.2 0.0 0.0014 18.1 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 PVD21343.1 - 0.00033 20.0 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PVD21343.1 - 0.0017 18.4 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 PVD21343.1 - 0.0031 17.1 4.1 0.0095 15.5 0.3 3.3 4 1 0 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 PVD21343.1 - 0.011 16.0 0.7 0.16 12.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 PVD21343.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 PVD21343.1 - 0.065 12.2 0.5 8.1 5.3 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 PVD21343.1 - 0.094 13.1 0.8 0.25 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PVD21343.1 - 0.11 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Octopine_DH PF02317.17 PVD21343.1 - 0.15 12.1 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain AAA_11 PF13086.6 PVD21344.1 - 8.3e-12 45.4 0.4 8.3e-12 45.4 0.4 3.2 2 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PVD21344.1 - 9.8e-07 29.2 0.0 2.8e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD21344.1 - 2.3e-05 24.2 0.0 5.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD21344.1 - 0.00031 20.2 0.4 0.004 16.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 PVD21344.1 - 0.00042 20.4 1.9 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 PVD21344.1 - 0.0017 17.9 11.7 0.019 14.5 11.7 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 PVD21344.1 - 0.0019 17.5 0.0 0.0019 17.5 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 PVD21344.1 - 0.04 13.6 0.4 6.4 6.4 0.0 3.5 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) DEAD PF00270.29 PVD21344.1 - 0.061 13.1 0.2 0.32 10.8 0.1 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 PVD21344.1 - 0.12 12.8 4.8 0.53 10.6 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain RNA_pol_3_Rpc31 PF11705.8 PVD21344.1 - 0.54 10.5 16.2 0.13 12.5 12.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.14 PVD21345.1 - 9 6.8 32.1 0.55 10.7 6.9 2.7 2 1 0 2 2 2 0 Prothymosin/parathymosin family Roughex PF06020.11 PVD21347.1 - 0.0092 15.1 0.2 0.012 14.8 0.2 1.0 1 0 0 1 1 1 1 Drosophila roughex protein DUF3245 PF11595.8 PVD21347.1 - 0.099 13.1 0.4 0.12 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ldl_recept_a PF00057.18 PVD21350.1 - 0.0021 18.2 9.7 0.0044 17.2 9.7 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD21350.1 - 0.01 16.1 0.8 0.025 14.9 0.1 1.9 2 0 0 2 2 2 0 CUB domain Crisp PF08562.10 PVD21350.1 - 7 7.3 10.8 2 9.1 6.1 2.2 2 0 0 2 2 2 0 Crisp CD20 PF04103.15 PVD21352.1 - 0.17 11.9 5.0 0.19 11.8 3.7 1.8 2 1 0 2 2 2 0 CD20-like family EphA2_TM PF14575.6 PVD21352.1 - 0.69 10.8 3.6 4 8.4 3.6 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M41 PF01434.18 PVD21354.1 - 7.8e-52 175.9 2.4 1.3e-50 171.9 2.4 2.2 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PVD21354.1 - 1.3e-43 148.5 0.0 2.9e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD21354.1 - 1.5e-14 53.5 0.1 4.7e-14 51.9 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 PVD21354.1 - 4.1e-11 43.2 0.2 1.1e-10 41.8 0.2 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 PVD21354.1 - 0.00023 21.2 0.2 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD21354.1 - 0.00033 21.0 0.0 0.087 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 PVD21354.1 - 0.00063 20.2 0.8 0.36 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 PVD21354.1 - 0.0012 18.6 0.1 0.017 14.9 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PVD21354.1 - 0.0016 18.5 0.0 0.0079 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sec7 PF01369.20 PVD21354.1 - 0.0031 17.2 0.2 0.0089 15.7 0.0 1.8 2 0 0 2 2 1 1 Sec7 domain TIP49 PF06068.13 PVD21354.1 - 0.006 15.8 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PVD21354.1 - 0.011 16.3 0.3 0.77 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD21354.1 - 0.013 15.8 0.3 0.24 11.8 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 PVD21354.1 - 0.029 14.1 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PVD21354.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PVD21354.1 - 0.079 13.1 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PVD21354.1 - 0.08 13.2 0.4 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain SH3_4 PF06347.13 PVD21354.1 - 0.12 12.2 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_14 PF13173.6 PVD21354.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF5595 PF18077.1 PVD21354.1 - 0.61 10.2 5.7 2.2 8.4 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) PUF PF00806.19 PVD21355.1 - 1e-12 47.0 12.5 7.5e-05 22.2 0.0 8.4 10 0 0 10 10 10 4 Pumilio-family RNA binding repeat DUF2052 PF09747.9 PVD21355.1 - 1.3 9.1 9.0 1.1 9.3 6.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UPF0489 PF12640.7 PVD21356.1 - 4.9e-50 170.2 0.0 1.1e-49 169.1 0.0 1.6 1 0 0 1 1 1 1 UPF0489 domain Med11 PF10280.9 PVD21356.1 - 0.17 12.3 2.2 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Mediator complex protein Alpha_kinase PF02816.18 PVD21357.1 - 4.7e-15 56.2 0.7 4.6e-14 53.0 0.8 2.0 1 1 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 PVD21358.1 - 2e-16 60.7 0.2 2.5e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family RcsD_ABL PF16359.5 PVD21358.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 RcsD-ABL domain TPR_11 PF13414.6 PVD21359.1 - 4.6e-07 29.4 0.1 0.096 12.4 0.0 3.8 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 PVD21359.1 - 6.9e-07 28.8 2.5 0.21 11.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD21359.1 - 3.1e-06 27.5 1.9 0.00067 20.3 0.1 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD21359.1 - 9.3e-06 25.5 0.1 0.96 9.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD21359.1 - 3.8e-05 24.1 0.4 0.017 15.6 0.1 3.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD21359.1 - 0.0001 22.5 5.2 0.1 12.9 2.3 4.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD21359.1 - 0.00086 19.2 10.1 0.013 15.6 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD21359.1 - 0.017 15.1 0.0 0.017 15.1 0.0 3.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 PVD21359.1 - 0.021 15.4 2.0 0.085 13.5 0.5 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 PVD21359.1 - 0.023 13.9 0.2 0.051 12.8 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD21359.1 - 0.034 14.8 2.3 0.06 14.0 0.1 2.6 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD21359.1 - 0.042 14.1 0.7 0.7 10.2 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PVD21359.1 - 0.049 14.0 0.1 3.4 8.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Alpha-2-MRAP_N PF06400.11 PVD21359.1 - 0.05 13.6 0.2 0.092 12.7 0.2 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain TPR_10 PF13374.6 PVD21359.1 - 0.077 12.9 0.5 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PBP1_TM PF14812.6 PVD21361.1 - 0.79 10.1 14.7 0.48 10.8 5.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfotransfer_3 PF13469.6 PVD21362.1 - 9.9e-11 42.4 2.7 6.4e-05 23.4 0.3 3.7 2 1 0 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD21362.1 - 1.1e-09 38.2 0.0 3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain SH3_9 PF14604.6 PVD21363.1 - 2.1e-12 46.7 0.0 3.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD21363.1 - 8.1e-11 41.4 0.0 1.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD21363.1 - 1.4e-08 34.2 0.0 3.8e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CAS_C PF12026.8 PVD21364.1 - 1.1e-59 202.0 3.1 1.1e-59 202.0 3.1 2.4 2 1 0 2 2 2 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 PVD21364.1 - 1.4e-44 151.9 0.9 2.7e-44 150.9 0.9 1.5 1 0 0 1 1 1 1 Serine rich protein interaction domain CD99L2 PF12301.8 PVD21364.1 - 0.013 15.8 0.5 0.027 14.8 0.5 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 GP40 PF11025.8 PVD21364.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium ThylakoidFormat PF11264.8 PVD21365.1 - 0.025 14.3 0.0 0.03 14.0 0.0 1.0 1 0 0 1 1 1 0 Thylakoid formation protein Mito_fiss_reg PF05308.11 PVD21365.1 - 0.24 11.5 10.0 0.28 11.3 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CARMIL_C PF16000.5 PVD21367.1 - 3.1e-38 132.1 10.2 2.6e-30 106.1 1.4 5.1 1 1 3 5 5 5 2 CARMIL C-terminus Carm_PH PF17888.1 PVD21367.1 - 5.2e-30 103.7 0.4 1.4e-29 102.3 0.4 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 PVD21367.1 - 3.7e-12 45.3 23.9 0.0014 18.5 0.1 9.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 PVD21367.1 - 3.7e-08 33.5 16.2 0.043 14.2 0.1 6.5 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD21367.1 - 0.0012 19.1 7.2 8 7.4 0.0 7.0 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 PVD21367.1 - 0.049 13.4 19.2 1.6 8.5 0.3 6.7 5 2 1 6 6 6 0 Leucine rich repeat TPT PF03151.16 PVD21368.1 - 6.2e-23 81.6 17.3 7.4e-23 81.3 17.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD21368.1 - 1.7e-05 25.0 27.5 0.0017 18.5 7.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family RNase_Zc3h12a PF11977.8 PVD21369.1 - 5.9e-55 185.3 0.0 1.8e-54 183.8 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 PVD21369.1 - 0.0032 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein-only RNase P DUF5615 PF18480.1 PVD21369.1 - 0.066 13.0 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) RNase_Zc3h12a_2 PF14626.6 PVD21369.1 - 0.071 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain RNF220 PF15926.5 PVD21370.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 PVD21370.1 - 0.086 13.2 1.4 0.13 12.5 1.4 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Aa_trans PF01490.18 PVD21371.1 - 1e-41 143.0 19.9 1.5e-41 142.5 19.9 1.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein FANCL_C PF11793.8 PVD21371.1 - 0.0047 17.1 0.4 0.013 15.7 0.4 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain DUF2976 PF11190.8 PVD21371.1 - 0.052 13.3 0.1 0.052 13.3 0.1 3.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2976) DUF872 PF05915.12 PVD21371.1 - 0.7 10.1 4.8 1.4 9.1 0.4 3.1 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) EF-hand_1 PF00036.32 PVD21372.1 - 2.2e-24 83.1 6.2 7.3e-10 37.7 1.7 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PVD21372.1 - 1.1e-23 83.4 2.7 6.9e-18 64.9 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD21372.1 - 6.6e-21 73.9 6.5 9.5e-15 54.2 0.3 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD21372.1 - 8.3e-20 69.0 1.0 1.5e-06 27.7 0.0 3.2 2 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PVD21372.1 - 1.3e-14 52.9 2.5 2.2e-05 23.7 0.6 3.3 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 PVD21372.1 - 3.9e-11 42.8 0.7 8.5e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PVD21372.1 - 1.7e-07 31.4 0.2 3.7e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 PVD21372.1 - 0.00041 21.2 0.0 0.00083 20.2 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD21372.1 - 0.00058 20.2 0.1 0.0097 16.2 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD21372.1 - 0.001 19.2 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 PVD21372.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 Ca2+ insensitive EF hand DUF5580 PF17743.1 PVD21372.1 - 0.003 16.2 0.0 0.0033 16.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Fer2_2 PF01799.20 PVD21372.1 - 0.021 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 [2Fe-2S] binding domain ExbD PF02472.16 PVD21372.1 - 0.026 14.7 0.0 3.4 7.8 0.0 2.1 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR DUF853 PF05872.12 PVD21372.1 - 0.027 13.1 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2267 PF10025.9 PVD21372.1 - 0.057 13.7 0.2 2.1 8.7 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DED PF01335.21 PVD21372.1 - 0.066 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Death effector domain DUF1296 PF06972.11 PVD21372.1 - 0.08 13.1 0.1 0.37 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) VCBS PF13517.6 PVD21372.1 - 0.093 13.3 0.7 2.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LicD PF04991.13 PVD21373.1 - 1.4e-16 61.3 0.0 2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 LicD family LicD PF04991.13 PVD21374.1 - 3.3e-21 76.5 0.1 2.3e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 LicD family LicD PF04991.13 PVD21375.1 - 9.8e-22 78.2 0.2 2.3e-16 60.6 0.5 2.3 1 1 1 2 2 2 2 LicD family LicD PF04991.13 PVD21376.1 - 8.4e-19 68.6 0.2 1.7e-14 54.5 0.1 2.3 2 0 0 2 2 2 2 LicD family VIT_2 PF13757.6 PVD21376.1 - 0.053 13.4 0.4 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain LicD PF04991.13 PVD21377.1 - 8.9e-23 81.6 0.0 1.5e-15 57.9 0.0 2.2 2 0 0 2 2 2 2 LicD family LicD PF04991.13 PVD21378.1 - 7.9e-23 81.8 0.1 1.1e-15 58.4 0.2 2.2 1 1 1 2 2 2 2 LicD family LicD PF04991.13 PVD21379.1 - 3.6e-17 63.3 0.1 4.6e-17 62.9 0.1 1.4 1 1 0 1 1 1 1 LicD family MORN PF02493.20 PVD21383.1 - 3e-14 52.0 19.0 0.00028 20.6 0.2 3.6 3 0 0 3 3 3 3 MORN repeat Alanine_zipper PF11839.8 PVD21383.1 - 0.15 12.4 16.6 0.39 11.1 16.6 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein MORN PF02493.20 PVD21384.1 - 1.1e-19 69.1 49.1 1.4e-05 24.7 5.1 5.9 6 0 0 6 6 6 5 MORN repeat 4HBT_3 PF13622.6 PVD21385.1 - 1.4e-57 195.8 0.4 1.6e-57 195.6 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 PVD21385.1 - 1e-33 116.0 0.1 1.3e-25 89.8 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase Kelch_4 PF13418.6 PVD21386.1 - 9.4e-38 128.0 0.4 5.6e-10 39.1 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD21386.1 - 1.7e-31 107.9 11.8 6.2e-07 29.5 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD21386.1 - 4.9e-23 80.6 0.6 8.5e-06 25.6 0.2 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PVD21386.1 - 2.2e-20 72.1 2.9 6.9e-06 26.2 0.0 6.4 4 2 2 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PVD21386.1 - 1.3e-18 66.2 9.3 6.5e-05 22.7 0.0 7.3 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PVD21386.1 - 1.2e-13 50.4 8.4 1.4e-06 27.8 0.0 6.9 7 1 0 7 7 7 3 Kelch motif DUF4110 PF13422.6 PVD21386.1 - 0.0033 17.5 0.0 0.0033 17.5 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) zf-C2H2 PF00096.26 PVD21387.1 - 1.2e-37 126.3 96.8 0.00046 20.5 0.6 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21387.1 - 4.4e-34 114.2 86.7 0.0033 18.1 0.4 12.7 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD21387.1 - 1.1e-32 110.9 84.9 2.2e-07 31.0 0.0 13.3 13 0 0 13 13 13 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD21387.1 - 3.8e-10 39.5 77.4 6.9e-05 22.7 3.3 12.3 11 1 1 12 12 12 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21387.1 - 2.1e-09 37.4 66.2 0.036 14.4 1.8 10.5 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 PVD21387.1 - 4.6e-08 33.4 52.6 0.032 14.7 0.0 10.1 7 3 3 10 10 10 4 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 PVD21387.1 - 4e-05 23.8 1.4 0.23 11.8 0.1 3.2 2 1 0 2 2 2 2 BolA-like protein zf-C2H2_11 PF16622.5 PVD21387.1 - 0.0012 18.5 49.5 0.016 15.0 0.1 9.8 9 1 1 10 10 10 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PVD21387.1 - 0.0024 18.2 55.1 0.17 12.2 0.3 9.0 2 2 6 8 8 8 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PVD21387.1 - 0.019 15.4 50.3 0.15 12.5 0.2 8.9 9 0 0 9 9 8 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 PVD21387.1 - 0.042 14.6 40.5 0.67 10.7 0.8 6.2 4 2 2 6 6 6 0 zinc-ribbon family GAGA PF09237.11 PVD21387.1 - 0.22 11.3 6.2 13 5.7 1.2 3.8 3 0 0 3 3 3 0 GAGA factor zf_UBZ PF18439.1 PVD21387.1 - 0.34 10.5 44.6 1.5 8.5 0.1 9.5 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 PVD21387.1 - 0.97 9.5 32.6 0.12 12.4 0.8 5.9 2 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_ZIC PF18366.1 PVD21387.1 - 3.5 7.8 17.4 14 5.9 0.3 6.2 5 1 1 6 6 6 0 Zic proteins zinc finger domain EF-hand_1 PF00036.32 PVD21388.1 - 2.4e-26 89.3 7.2 1e-06 27.8 0.2 5.3 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 PVD21388.1 - 8.6e-26 87.6 6.9 2.1e-05 24.1 0.1 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 PVD21388.1 - 6.9e-22 77.7 15.0 4.7e-11 43.0 1.2 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PVD21388.1 - 1.3e-20 71.9 9.5 5.7e-05 22.4 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 PVD21388.1 - 3.1e-12 46.2 7.6 0.00042 20.1 0.5 5.0 4 1 1 5 5 5 4 EF-hand domain pair Dockerin_1 PF00404.18 PVD21388.1 - 0.00072 19.7 0.8 0.55 10.5 0.1 3.4 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_10 PF14788.6 PVD21388.1 - 0.00079 19.2 6.3 12 5.8 0.0 4.5 4 1 1 5 5 5 1 EF hand SPARC_Ca_bdg PF10591.9 PVD21388.1 - 0.0021 18.4 11.0 0.064 13.6 1.9 4.2 2 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PVD21388.1 - 0.0025 18.1 0.0 17 5.8 0.0 4.0 5 0 0 5 5 4 0 EF-hand domain Toprim_2 PF13155.6 PVD21388.1 - 0.0067 16.8 0.2 1 9.8 0.0 3.0 1 1 2 3 3 3 1 Toprim-like EF-hand_13 PF17958.1 PVD21388.1 - 0.038 13.8 0.2 1.5 8.7 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain PHB_acc_N PF07879.11 PVD21388.1 - 0.093 12.8 0.9 3.2 7.9 0.1 3.2 2 1 1 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain UPF0149 PF03695.13 PVD21388.1 - 0.15 12.3 2.7 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) GPHH PF16905.5 PVD21388.1 - 0.18 11.6 0.0 0.66 9.8 0.0 2.0 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Glyco_transf_92 PF01697.27 PVD21390.1 - 0.00023 20.9 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 zf-C2H2_4 PF13894.6 PVD21391.1 - 0.00052 20.6 6.1 0.009 16.8 0.1 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD21391.1 - 0.011 16.2 0.1 0.011 16.2 0.1 6.7 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF629 PF04780.12 PVD21391.1 - 0.02 13.5 13.3 1.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 PVD21391.1 - 0.15 11.9 16.4 3.9 7.4 0.0 5.4 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 PVD21391.1 - 0.32 11.3 12.1 3.4 8.0 4.2 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon SMN PF06003.12 PVD21391.1 - 0.5 9.6 8.1 1.3 8.2 8.1 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-C2H2_jaz PF12171.8 PVD21391.1 - 0.65 10.4 24.4 0.052 13.9 3.6 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SBF PF01758.16 PVD21392.1 - 1.6e-11 44.3 6.8 1.6e-11 44.3 6.8 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family YlqD PF11068.8 PVD21392.1 - 0.044 14.2 0.6 0.11 12.8 0.6 1.7 1 0 0 1 1 1 0 YlqD protein Sec34 PF04136.15 PVD21392.1 - 0.095 12.6 6.6 0.043 13.7 3.8 1.8 2 0 0 2 2 2 0 Sec34-like family P4Ha_N PF08336.11 PVD21392.1 - 4 7.5 8.8 32 4.5 0.1 3.5 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2062 PF09835.9 PVD21392.1 - 9.7 6.0 8.4 5.2 6.9 5.9 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) zf-C2H2 PF00096.26 PVD21393.1 - 2e-22 78.3 31.4 3.5e-05 24.0 0.8 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD21393.1 - 3.1e-18 65.3 31.7 1.1e-07 32.0 0.6 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD21393.1 - 4.4e-18 64.4 30.8 0.00051 20.7 0.8 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21393.1 - 2.7e-13 49.8 12.3 0.003 17.8 0.0 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD21393.1 - 9.4e-08 32.2 16.4 0.02 15.3 0.5 5.6 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD21393.1 - 2.3e-05 24.3 27.0 0.014 15.3 0.5 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD21393.1 - 0.0022 18.2 1.8 0.0022 18.2 1.8 3.7 3 1 1 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 PVD21393.1 - 0.0049 16.9 19.2 0.52 10.5 0.8 4.9 3 1 1 4 4 4 3 Zinc ribbon domain SUIM_assoc PF16619.5 PVD21393.1 - 0.08 13.0 1.4 0.26 11.4 1.4 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Elf1 PF05129.13 PVD21393.1 - 0.1 12.7 17.3 0.2 11.7 0.7 3.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 PVD21393.1 - 0.68 10.3 18.6 0.64 10.4 0.6 4.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 PVD21393.1 - 2.5 8.2 25.9 0.81 9.8 0.1 5.3 2 2 3 5 5 5 0 BED zinc finger zf-LYAR PF08790.11 PVD21393.1 - 3.4 7.7 7.6 10 6.1 0.7 3.7 3 1 1 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 PVD21393.1 - 7.1 6.5 26.4 1.1 9.1 0.4 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF4764 PF15961.5 PVD21393.1 - 8.9 4.9 8.8 3.1 6.4 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 PVD21394.1 - 8.8e-22 76.3 30.5 4.7e-05 23.6 0.8 6.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD21394.1 - 3.4e-19 68.3 30.2 7.7e-08 32.4 0.6 5.8 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD21394.1 - 1.2e-15 56.9 35.7 0.0007 20.2 0.8 6.3 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21394.1 - 1.9e-13 50.3 10.1 0.004 17.4 0.0 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD21394.1 - 5.2e-10 39.4 15.4 0.037 14.4 0.4 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD21394.1 - 0.00012 22.0 31.7 0.054 13.5 0.6 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD21394.1 - 0.00089 19.5 16.7 0.0018 18.6 1.7 3.6 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 PVD21394.1 - 0.056 13.5 16.6 0.3 11.1 0.4 3.5 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 PVD21394.1 - 1.6 9.1 15.8 5 7.5 0.9 4.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) BES1_N PF05687.13 PVD21394.1 - 9.4 6.6 7.7 1.2 9.6 1.5 2.7 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal zf-BED PF02892.15 PVD21394.1 - 9.5 6.3 21.7 1.5 8.9 0.2 5.4 2 2 3 5 5 5 0 BED zinc finger Ge1_WD40 PF16529.5 PVD21395.1 - 8.9e-120 399.6 0.0 1.5e-119 398.9 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 PVD21395.1 - 0.0072 17.2 0.0 0.089 13.7 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF5341 PF17276.2 PVD21395.1 - 4.4 7.5 5.6 9.1 6.4 0.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5341) zf-H2C2_2 PF13465.6 PVD21396.1 - 8.3e-53 174.6 89.0 3.8e-09 36.6 1.3 12.2 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21396.1 - 5.3e-36 121.1 100.1 0.00062 20.1 1.0 11.5 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21396.1 - 6.3e-25 85.7 93.2 0.003 18.3 2.4 11.6 11 0 0 11 11 11 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD21396.1 - 6e-16 57.9 86.6 9e-06 25.3 1.8 11.1 11 0 0 11 11 11 7 C2H2-type zinc-finger domain GAGA PF09237.11 PVD21396.1 - 0.0023 17.7 24.5 1.9 8.3 0.2 6.5 3 1 4 7 7 7 3 GAGA factor zf-C2H2_2 PF12756.7 PVD21396.1 - 0.0057 17.0 2.4 0.0057 17.0 2.4 8.3 2 1 5 8 8 7 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PVD21396.1 - 0.0063 16.8 1.9 0.0063 16.8 1.9 9.8 9 1 1 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD21396.1 - 0.048 13.4 0.4 0.048 13.4 0.4 8.8 10 0 0 10 10 9 0 zinc-finger C2H2-type zf_C2H2_10 PF18414.1 PVD21396.1 - 0.092 12.3 6.5 3.8 7.1 0.5 4.0 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-met PF12874.7 PVD21396.1 - 0.093 13.2 0.3 0.093 13.2 0.3 8.4 10 0 0 10 10 8 0 Zinc-finger of C2H2 type FOXO_KIX_bdg PF16675.5 PVD21396.1 - 0.16 12.3 2.9 0.46 10.8 1.1 2.6 2 0 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 PriA_CRR PF18319.1 PVD21396.1 - 0.19 11.7 0.1 0.19 11.7 0.1 7.4 9 0 0 9 9 9 0 PriA DNA helicase Cys-rich region (CRR) domain BolA PF01722.18 PVD21396.1 - 2.5 8.4 13.0 1.8 8.9 0.1 3.3 3 0 0 3 3 2 0 BolA-like protein Myosin_tail_1 PF01576.19 PVD21397.1 - 3.5e-10 38.4 38.0 4.8e-10 38.0 38.0 1.1 1 0 0 1 1 1 1 Myosin tail TMF_TATA_bd PF12325.8 PVD21397.1 - 0.0026 18.0 32.7 0.047 13.9 4.9 3.7 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding Filament PF00038.21 PVD21397.1 - 0.0029 17.3 31.9 0.0083 15.7 31.9 2.3 1 1 0 1 1 1 1 Intermediate filament protein Fib_alpha PF08702.10 PVD21397.1 - 0.0059 16.8 18.4 0.12 12.5 3.1 3.2 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 PVD21397.1 - 0.0093 16.3 10.6 0.0093 16.3 10.6 4.2 1 1 4 5 5 5 3 Uso1 / p115 like vesicle tethering protein, C terminal region PLAC9 PF15205.6 PVD21397.1 - 0.018 15.4 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF4140 PF13600.6 PVD21397.1 - 0.029 14.8 2.3 0.029 14.8 2.3 4.4 1 1 4 5 5 5 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 PVD21397.1 - 0.034 14.2 2.1 0.034 14.2 2.1 5.1 5 1 0 5 5 5 0 bZIP transcription factor HALZ PF02183.18 PVD21397.1 - 0.037 14.2 2.2 0.037 14.2 2.2 4.3 5 0 0 5 5 4 0 Homeobox associated leucine zipper GAS PF13851.6 PVD21397.1 - 0.045 13.1 30.1 1.7 7.9 20.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 PVD21397.1 - 0.049 13.7 34.9 0.055 13.5 6.4 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 PVD21397.1 - 0.052 14.0 17.1 0.8 10.2 0.3 4.9 3 2 2 6 6 5 0 Flagella accessory protein C (FlaC) YabA PF06156.13 PVD21397.1 - 0.052 14.2 23.6 0.17 12.5 3.7 3.9 1 1 2 3 3 3 0 Initiation control protein YabA BLOC1_2 PF10046.9 PVD21397.1 - 0.056 13.8 13.4 0.28 11.5 0.4 3.8 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Leu_zip PF15294.6 PVD21397.1 - 0.071 12.6 25.6 0.066 12.7 21.1 2.2 1 1 1 2 2 2 0 Leucine zipper CEP63 PF17045.5 PVD21397.1 - 0.074 12.9 33.7 0.037 13.9 8.6 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa KASH_CCD PF14662.6 PVD21397.1 - 0.12 12.2 37.5 1.9 8.3 20.3 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 PVD21397.1 - 0.24 10.2 33.9 3 6.6 15.4 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 PVD21397.1 - 0.38 11.4 34.7 2.3 8.9 11.6 3.6 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 PVD21397.1 - 0.46 9.8 22.6 0.094 12.1 3.6 2.3 1 1 1 2 2 2 0 FAM76 protein DUF1664 PF07889.12 PVD21397.1 - 0.49 10.4 15.0 1.2 9.2 5.5 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 PVD21397.1 - 0.63 9.2 37.6 0.82 8.8 33.8 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ZapB PF06005.12 PVD21397.1 - 0.7 10.4 40.9 1.8 9.0 5.1 5.5 2 2 2 4 4 3 0 Cell division protein ZapB Tup_N PF08581.10 PVD21397.1 - 0.87 9.9 29.8 3.4 8.0 2.3 4.6 3 2 2 5 5 5 0 Tup N-terminal Pox_A_type_inc PF04508.12 PVD21397.1 - 0.89 9.5 0.1 0.89 9.5 0.1 4.2 5 1 0 5 5 2 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 PVD21397.1 - 0.94 9.5 35.5 2.9 7.9 20.7 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 PVD21397.1 - 1.1 8.6 31.4 0.33 10.4 19.3 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4559 PF15112.6 PVD21397.1 - 2 8.0 15.7 0.12 12.0 8.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Ax_dynein_light PF10211.9 PVD21397.1 - 2.4 8.1 29.1 1.5 8.7 8.1 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain Baculo_PEP_C PF04513.12 PVD21397.1 - 2.8 8.0 11.3 9.7 6.2 0.9 3.1 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GIT_CC PF16559.5 PVD21397.1 - 3.1 7.7 23.1 0.47 10.4 0.9 4.7 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor LtuB PF17455.2 PVD21397.1 - 3.2 8.4 5.5 2.1 9.0 2.6 2.2 1 1 0 2 2 1 0 Late transcription unit B TBCA PF02970.16 PVD21397.1 - 3.7 7.9 20.6 2.2e+02 2.3 8.0 4.3 1 1 1 2 2 1 0 Tubulin binding cofactor A DUF3584 PF12128.8 PVD21397.1 - 3.8 4.9 34.0 37 1.6 34.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 PVD21397.1 - 3.9 6.5 29.0 0.17 10.9 17.3 2.7 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 PVD21397.1 - 4.4 5.8 21.1 1.7 7.1 2.1 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 PVD21397.1 - 4.7 8.2 37.1 0.8 10.6 7.3 3.8 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Golgin_A5 PF09787.9 PVD21397.1 - 5.2 6.4 35.7 1.6 8.1 9.4 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF3450 PF11932.8 PVD21397.1 - 5.7 6.2 33.0 1.7 7.9 8.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Occludin_ELL PF07303.13 PVD21397.1 - 5.7 7.7 17.1 20 6.0 2.7 3.9 1 1 3 4 4 4 0 Occludin homology domain EMP24_GP25L PF01105.24 PVD21397.1 - 6.1 6.7 18.3 0.067 13.1 0.6 3.1 2 1 0 2 2 1 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.14 PVD21397.1 - 7.6 6.3 28.0 1.5 8.7 6.2 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 PVD21397.1 - 9.6 6.4 28.4 1 9.6 8.5 4.5 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Trypsin PF00089.26 PVD21398.1 - 1.3e-38 133.1 0.0 1.6e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD21398.1 - 2.5e-06 27.8 0.0 5.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD21398.1 - 0.0034 18.3 0.0 0.008 17.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PVD21399.1 - 4.9e-47 160.6 0.0 6.9e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD21399.1 - 2.1e-06 28.1 0.0 5.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD21399.1 - 0.0007 20.5 0.0 0.0014 19.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain ORF11CD3 PF10549.9 PVD21400.1 - 0.14 12.3 0.1 0.4 10.8 0.1 1.7 2 0 0 2 2 2 0 ORF11CD3 domain SQS_PSY PF00494.19 PVD21402.1 - 2.4e-49 168.2 0.1 4.1e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase WD40 PF00400.32 PVD21402.1 - 4.5e-19 68.4 3.4 1.5e-05 25.7 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21402.1 - 0.012 15.8 0.1 11 6.4 0.0 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Beta-lactamase PF00144.24 PVD21403.1 - 1.3e-42 146.3 0.0 2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 PVD21403.1 - 0.00058 19.6 0.1 1.9 8.4 0.0 3.2 3 0 0 3 3 3 2 Bacterial tandem repeat domain 1 DUF4665 PF15679.5 PVD21404.1 - 0.03 14.9 0.2 0.05 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) Yeast-kill-tox PF09207.11 PVD21404.1 - 0.13 12.9 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 Yeast killer toxin PH_RBD PF12068.8 PVD21405.1 - 0.068 12.6 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Rab-binding domain (RBD) Pkinase_Tyr PF07714.17 PVD21406.1 - 2.7e-41 141.6 2.7 2.4e-22 79.5 0.1 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PVD21406.1 - 7.1e-26 91.1 0.0 4.5e-13 49.2 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21407.1 - 1.2e-33 116.5 0.8 7e-27 94.3 0.3 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD21407.1 - 2.5e-17 63.1 1.0 5.6e-15 55.4 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain KELK PF15796.5 PVD21407.1 - 0.022 15.2 1.6 3.1 8.3 0.1 3.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NosD PF05048.13 PVD21408.1 - 0.2 10.9 1.2 0.39 9.9 1.0 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Pkinase_Tyr PF07714.17 PVD21409.1 - 8.3e-48 162.9 0.0 8e-25 87.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD21409.1 - 2e-29 102.7 0.0 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APG17 PF04108.12 PVD21409.1 - 0.0091 15.2 0.5 0.016 14.3 0.5 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 ubiquitin PF00240.23 PVD21410.1 - 6.2e-23 80.3 0.2 7.4e-23 80.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD21410.1 - 4.1e-13 49.0 0.2 4.3e-13 48.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PVD21410.1 - 3e-05 23.8 0.0 3.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 PVD21410.1 - 3.1e-05 24.3 0.1 8.3e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain zf-H2C2_2 PF13465.6 PVD21411.1 - 3.9e-36 121.9 52.7 6.9e-07 29.4 0.0 10.7 11 0 0 11 11 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21411.1 - 3.4e-29 99.6 66.1 3e-06 27.4 0.9 10.5 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21411.1 - 2.4e-24 83.9 65.0 0.0012 19.5 0.9 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD21411.1 - 2e-08 34.0 58.0 0.00013 21.8 0.2 10.2 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD21411.1 - 6.9e-05 23.0 34.7 1.5 9.2 0.5 9.5 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD21411.1 - 0.00031 21.0 42.3 3.4 8.2 0.8 9.1 9 0 0 9 9 9 3 Zinc-finger of C2H2 type CpXC PF14353.6 PVD21411.1 - 0.0024 17.9 0.1 0.0024 17.9 0.1 7.2 3 2 4 8 8 8 1 CpXC protein Zn-ribbon_8 PF09723.10 PVD21411.1 - 0.016 15.3 30.0 0.084 13.0 0.4 6.7 4 3 3 7 7 7 0 Zinc ribbon domain zf-Di19 PF05605.12 PVD21411.1 - 0.019 15.3 37.6 6 7.2 6.0 7.0 5 2 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 PVD21411.1 - 0.033 14.9 27.5 2.2 9.0 1.1 6.0 2 2 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 PVD21411.1 - 0.055 13.5 24.7 1.6 8.8 0.7 5.1 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 PVD21411.1 - 0.1 12.2 34.0 3.2 7.4 0.0 9.0 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zf-UBP PF02148.19 PVD21411.1 - 0.19 12.1 32.9 7e+02 0.6 16.4 5.8 2 2 0 2 2 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.15 PVD21411.1 - 0.26 11.3 0.2 0.26 11.3 0.2 7.1 7 1 0 7 7 6 0 BED zinc finger DZR PF12773.7 PVD21411.1 - 0.32 11.1 31.9 11 6.2 5.4 5.7 2 2 1 3 3 2 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 PVD21411.1 - 0.65 10.1 23.9 11 6.1 0.0 4.4 2 1 2 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_8 PF15909.5 PVD21411.1 - 0.98 9.8 28.0 2.5 8.5 2.7 5.2 2 1 3 5 5 5 0 C2H2-type zinc ribbon zf_C2H2_13 PF18508.1 PVD21411.1 - 1.3 8.7 9.7 47 3.7 0.0 5.7 6 0 0 6 6 5 0 Zinc finger domain zf-C2H2_9 PF16293.5 PVD21411.1 - 1.5 8.7 8.4 31 4.5 0.2 4.8 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) OrfB_Zn_ribbon PF07282.11 PVD21411.1 - 2.3 8.2 23.8 4 7.4 0.4 6.6 6 1 1 7 7 7 0 Putative transposase DNA-binding domain Rpr2 PF04032.16 PVD21411.1 - 3.9 7.8 27.0 26 5.2 1.1 5.6 1 1 1 2 2 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NIF PF03031.18 PVD21414.1 - 7.7e-14 51.7 0.1 2.7e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 PVD21414.1 - 0.00058 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme BRCT PF00533.26 PVD21414.1 - 0.00077 19.8 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PVD21414.1 - 0.0013 18.7 0.3 0.0031 17.4 0.3 1.7 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.6 PVD21414.1 - 0.12 12.2 0.0 3.7 7.4 0.0 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like DUF4541 PF15074.6 PVD21415.1 - 7.7e-18 64.9 1.1 1.4e-17 64.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) 7TM_GPCR_Srw PF10324.9 PVD21416.1 - 7.9e-06 25.4 7.3 1.7e-05 24.2 1.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srw PF10324.9 PVD21417.1 - 4.6e-06 26.1 1.4 5.7e-06 25.8 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Wzy_C PF04932.15 PVD21418.1 - 2.7 7.6 8.3 3.9 7.1 0.3 2.6 3 0 0 3 3 3 0 O-Antigen ligase TAS2R PF05296.13 PVD21419.1 - 0.0038 16.4 0.4 0.0038 16.4 0.4 1.9 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) FA_desaturase PF00487.24 PVD21419.1 - 0.14 11.9 2.3 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF4282 PF14110.6 PVD21419.1 - 0.37 11.5 4.5 1.2 9.9 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) 7TM_GPCR_Srw PF10324.9 PVD21420.1 - 3.9e-09 36.2 2.5 5.1e-09 35.9 2.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 PVD21420.1 - 0.00025 20.3 2.1 0.00032 19.9 2.0 1.3 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.21 PVD21420.1 - 0.0023 17.3 1.4 0.0031 16.9 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PMT_4TMC PF16192.5 PVD21420.1 - 0.092 12.3 4.8 0.14 11.7 4.8 1.3 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase 7TM_GPCR_Srw PF10324.9 PVD21421.1 - 4.2e-09 36.1 2.7 4.4e-09 36.1 1.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 PVD21421.1 - 0.0058 15.8 2.7 0.0058 15.8 2.7 2.5 2 1 0 2 2 2 1 Taste receptor protein (TAS2R) STE3 PF02076.15 PVD21421.1 - 0.029 13.6 2.1 0.033 13.4 0.9 1.7 1 1 1 2 2 2 0 Pheromone A receptor Sulfotransfer_1 PF00685.27 PVD21422.1 - 3.1e-19 69.5 0.0 2.4e-17 63.3 0.1 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD21422.1 - 2.4e-12 47.7 1.8 6.5e-09 36.5 0.5 3.0 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD21422.1 - 0.0033 17.4 0.3 0.0051 16.8 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family LicD PF04991.13 PVD21423.1 - 4.7e-08 33.5 0.3 2.4e-06 27.8 0.4 2.1 2 0 0 2 2 2 2 LicD family F-box-like PF12937.7 PVD21425.1 - 1.7e-09 37.4 0.6 2.6e-09 36.8 0.6 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD21425.1 - 3.7e-06 26.7 0.1 5.3e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD21425.1 - 0.00065 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 F-box 7tm_1 PF00001.21 PVD21426.1 - 4.8e-24 85.1 18.6 6.1e-24 84.8 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD21426.1 - 1.4e-15 57.4 22.0 2.7e-14 53.2 22.0 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD21426.1 - 3.4e-05 23.6 16.2 3.4e-05 23.6 16.2 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2933 PF11666.8 PVD21426.1 - 1.8 8.6 6.6 6.8 6.8 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) 7tm_1 PF00001.21 PVD21427.1 - 5.2e-27 94.8 21.9 6.4e-27 94.5 21.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD21427.1 - 6.5e-16 58.5 29.7 3.7e-14 52.7 29.7 2.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD21427.1 - 1.3e-07 31.5 14.8 1.3e-07 31.5 14.8 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cadherin_C_2 PF16492.5 PVD21427.1 - 0.045 14.5 1.2 1.2 10.0 0.2 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal 7tm_1 PF00001.21 PVD21428.1 - 4.6e-21 75.3 10.0 5.9e-21 75.0 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD21428.1 - 1.4e-15 57.4 15.1 1e-11 44.7 4.1 2.7 1 1 2 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD21428.1 - 4.3e-06 26.6 10.5 4.3e-06 26.6 10.5 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD21428.1 - 0.0005 19.9 1.8 0.0011 18.8 1.8 1.5 1 0 0 1 1 1 1 Olfactory receptor Cadherin_C_2 PF16492.5 PVD21428.1 - 0.073 13.8 2.0 1.4 9.7 0.1 3.2 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Tcf25 PF04910.14 PVD21429.1 - 1.3e-116 389.5 1.2 1.7e-116 389.2 1.2 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 PVD21429.1 - 0.085 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat NIPSNAP PF07978.13 PVD21430.1 - 1.6e-40 137.5 0.1 1.1e-18 67.3 0.0 2.9 3 0 0 3 3 3 2 NIPSNAP DUF4201 PF13870.6 PVD21431.1 - 4.3e-50 169.9 22.0 4.3e-50 169.9 22.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 PVD21431.1 - 0.0021 18.1 2.5 0.0021 18.1 2.5 3.0 3 1 0 3 3 3 1 TolA binding protein trimerisation DUF948 PF06103.11 PVD21431.1 - 1.3 9.3 5.1 2.5 8.4 0.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SNF PF00209.18 PVD21432.1 - 3.7e-172 573.7 31.5 4.8e-172 573.3 31.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF5558 PF17713.1 PVD21433.1 - 0.027 14.8 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5558) Cupin_8 PF13621.6 PVD21435.1 - 2.8e-18 66.6 0.0 6.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain GFO_IDH_MocA PF01408.22 PVD21435.1 - 3.6e-09 37.5 0.0 9.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD21435.1 - 8e-05 22.6 0.1 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 PVD21435.1 - 0.011 16.4 0.1 0.028 15.1 0.1 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GSH_synth_ATP PF03917.17 PVD21436.1 - 8e-121 403.3 0.0 9.6e-121 403.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 PVD21436.1 - 8.4e-31 106.5 0.2 1.7e-30 105.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase HEAT_EZ PF13513.6 PVD21437.1 - 3.8e-23 81.6 11.1 7.8e-05 23.1 0.0 10.7 9 4 4 13 13 11 5 HEAT-like repeat HEAT_2 PF13646.6 PVD21437.1 - 1.4e-16 60.6 7.7 3.1e-07 30.7 0.1 8.1 6 3 2 9 9 8 2 HEAT repeats HEAT PF02985.22 PVD21437.1 - 2e-15 55.6 18.5 8e-05 22.6 0.0 10.2 11 0 0 11 11 10 2 HEAT repeat IBN_N PF03810.19 PVD21437.1 - 5e-14 52.0 1.8 1.7e-11 43.9 0.6 4.1 5 0 0 5 5 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 PVD21437.1 - 4e-11 43.0 1.2 0.00098 18.9 0.7 6.5 5 2 1 7 7 7 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 PVD21437.1 - 6.9e-11 42.6 3.8 0.12 12.9 0.1 8.6 7 3 2 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PVD21437.1 - 1.1e-10 41.9 3.9 0.00028 20.9 0.0 5.1 5 3 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 PVD21437.1 - 1.9e-09 37.1 3.3 0.00046 19.4 0.0 5.5 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) DUF3730 PF12530.8 PVD21437.1 - 5.9e-09 35.8 9.9 0.15 11.6 0.9 5.9 5 1 1 6 6 6 3 Protein of unknown function (DUF3730) Adaptin_N PF01602.20 PVD21437.1 - 9.5e-08 31.0 13.1 0.0019 16.9 0.0 5.6 4 2 0 4 4 4 3 Adaptin N terminal region DUF3385 PF11865.8 PVD21437.1 - 1.7e-07 31.3 6.3 0.28 11.1 0.0 7.5 9 3 0 9 9 9 2 Domain of unknown function (DUF3385) V-ATPase_H_N PF03224.14 PVD21437.1 - 3.4e-07 29.9 3.3 0.14 11.5 0.1 5.2 4 2 1 5 5 5 2 V-ATPase subunit H Arm PF00514.23 PVD21437.1 - 4.2e-06 26.6 1.6 3.3 7.9 0.0 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 PVD21437.1 - 0.00014 21.2 3.5 0.62 9.2 0.2 4.6 3 1 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Xpo1 PF08389.12 PVD21437.1 - 0.00085 19.4 5.5 1.4 8.9 0.0 5.4 5 1 0 5 5 5 2 Exportin 1-like protein HEAT_PBS PF03130.16 PVD21437.1 - 0.0009 19.7 1.7 1.1 10.1 0.0 4.8 4 0 0 4 4 2 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 PVD21437.1 - 0.0013 18.9 7.3 5.3 7.3 0.0 5.5 6 0 0 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 PVD21437.1 - 0.0039 17.3 8.1 0.1 12.7 0.3 5.2 5 2 1 6 6 5 1 Parkin co-regulated protein Cse1 PF08506.10 PVD21437.1 - 0.032 13.1 0.4 0.17 10.7 0.1 2.4 2 0 0 2 2 2 0 Cse1 Telomere_reg-2 PF10193.9 PVD21437.1 - 0.074 13.5 3.2 13 6.2 0.0 4.7 5 0 0 5 5 5 0 Telomere length regulation protein Rcd1 PF04078.13 PVD21437.1 - 0.35 10.1 4.3 0.13 11.6 0.8 2.0 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like WAPL PF07814.13 PVD21437.1 - 0.83 8.4 6.6 1.8 7.3 0.6 3.8 4 1 0 4 4 4 0 Wings apart-like protein regulation of heterochromatin Sec7_N PF12783.7 PVD21437.1 - 2.4 8.1 8.9 12 5.8 0.0 4.9 6 0 0 6 6 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ubiquitin PF00240.23 PVD21438.1 - 2.2e-10 40.2 0.2 6.3e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PVD21438.1 - 0.0002 21.9 1.4 0.0003 21.3 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PVD21438.1 - 0.004 17.2 0.1 0.0088 16.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TFIIA PF03153.13 PVD21438.1 - 0.0061 16.6 12.6 0.0082 16.2 12.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AA_permease_2 PF13520.6 PVD21439.1 - 1.2e-25 90.2 22.3 1.8e-25 89.6 22.3 1.1 1 0 0 1 1 1 1 Amino acid permease EpsG PF14897.6 PVD21439.1 - 0.78 9.0 12.6 0.023 14.0 5.6 1.9 3 0 0 3 3 3 0 EpsG family DUF4454 PF14628.6 PVD21442.1 - 0.089 12.6 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) TEP1_N PF05386.11 PVD21443.1 - 1.3 8.7 5.2 12 5.6 3.1 2.2 2 0 0 2 2 2 0 TEP1 N-terminal domain SSF PF00474.17 PVD21444.1 - 5.5e-25 88.1 17.1 1.9e-20 73.1 12.5 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family SSF PF00474.17 PVD21445.1 - 5.2e-37 127.7 21.0 8.7e-37 126.9 21.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4579 PF15158.6 PVD21445.1 - 0.12 12.2 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) CCD48 PF15799.5 PVD21446.1 - 0.0095 14.3 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 MIP PF00230.20 PVD21447.1 - 9.2e-71 238.1 8.4 1.2e-70 237.8 8.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein UreF PF01730.16 PVD21447.1 - 0.0025 18.4 0.1 0.0044 17.6 0.1 1.3 1 0 0 1 1 1 1 UreF Ras PF00071.22 PVD21448.1 - 5.9e-18 65.0 0.1 1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PVD21448.1 - 0.0019 18.4 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EnY2 PF10163.9 PVD21449.1 - 1.2e-35 121.8 0.6 1.3e-35 121.6 0.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2294 PF10057.9 PVD21449.1 - 0.016 15.4 0.5 0.26 11.4 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) Sin3a_C PF16879.5 PVD21449.1 - 0.06 13.1 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Trm112p PF03966.16 PVD21450.1 - 3.9e-06 27.3 0.2 1e-05 26.0 0.2 1.9 1 1 0 1 1 1 1 Trm112p-like protein TTL PF03133.15 PVD21451.1 - 8.1e-90 300.9 1.2 1.1e-89 300.5 1.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD21451.1 - 8.1e-09 35.1 0.2 0.00027 20.3 0.1 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD21451.1 - 0.0016 17.7 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp MOSC_N PF03476.16 PVD21451.1 - 0.055 13.4 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain 3-PAP PF12578.8 PVD21451.1 - 0.055 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Myotubularin-associated protein Ish1 PF10281.9 PVD21451.1 - 0.059 13.7 0.4 3.2 8.1 0.0 3.1 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Cytochrom_C1 PF02167.15 PVD21452.1 - 6.6e-94 313.7 0.0 8.1e-94 313.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 PVD21452.1 - 7e-05 23.1 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PVD21452.1 - 0.0018 19.4 0.0 0.0036 18.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c Rad51 PF08423.11 PVD21454.1 - 5.3e-53 179.9 0.1 8.2e-53 179.3 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PVD21454.1 - 0.00022 20.8 0.1 0.00045 19.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF5056 PF16479.5 PVD21454.1 - 0.021 15.0 0.2 5.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Neur_chan_LBD PF02931.23 PVD21455.1 - 1.2e-42 145.8 1.5 2.3e-42 144.9 1.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21455.1 - 5.4e-10 39.7 0.9 8.6e-10 39.1 0.3 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF5336 PF17270.2 PVD21455.1 - 5.9 6.5 6.4 1.2 8.7 2.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5336) RYDR_ITPR PF01365.21 PVD21456.1 - 8.8e-26 90.6 18.7 1.2e-18 67.3 0.1 4.6 5 0 0 5 5 5 2 RIH domain RIH_assoc PF08454.11 PVD21456.1 - 1.8e-25 88.8 7.2 1.5e-21 76.1 0.7 4.4 4 0 0 4 4 4 2 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 PVD21456.1 - 6.1e-25 87.7 0.1 1.5e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 PVD21456.1 - 2.3e-06 27.6 4.6 0.021 14.6 0.8 3.7 2 1 0 2 2 2 2 MIR domain DUF3361 PF11841.8 PVD21456.1 - 0.05 13.6 0.3 0.89 9.5 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) 7TM_GPCR_Srw PF10324.9 PVD21458.1 - 7.3e-05 22.2 1.8 9.3e-05 21.8 1.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD21458.1 - 0.0012 18.3 2.6 0.0016 17.9 2.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Oxidored_q2 PF00420.24 PVD21458.1 - 0.13 11.9 2.8 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Laminin_G_3 PF13385.6 PVD21459.1 - 1.9e-08 34.6 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Transglut_N PF00868.20 PVD21460.1 - 7.4e-29 100.5 0.1 1.5e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 PVD21460.1 - 8.3e-18 64.9 0.3 1.8e-17 63.8 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 PVD21460.1 - 7.7e-16 58.1 0.0 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain MRJP PF03022.16 PVD21463.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 PVD21463.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region MRJP PF03022.16 PVD21464.1 - 6.8e-06 25.7 0.0 8.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SK_channel PF03530.14 PVD21466.1 - 1.5e-31 108.7 2.3 3.7e-31 107.5 2.3 1.7 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 PVD21466.1 - 2.9e-15 56.0 0.7 2.9e-15 56.0 0.7 2.7 3 0 0 3 3 3 1 Ion channel CaMBD PF02888.16 PVD21466.1 - 2.4e-09 37.3 0.4 5.4e-09 36.1 0.4 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans PF00520.31 PVD21466.1 - 0.0013 18.0 6.2 0.018 14.2 6.1 2.5 1 1 0 1 1 1 1 Ion transport protein GT-D PF08759.11 PVD21466.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold IRK PF01007.20 PVD21466.1 - 0.025 14.4 0.0 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Alpha-amylase PF00128.24 PVD21466.1 - 0.029 13.9 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain SK_channel PF03530.14 PVD21467.1 - 3e-32 111.0 4.6 8e-32 109.6 4.6 1.8 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 PVD21467.1 - 5e-14 52.0 0.5 2.4e-13 49.8 0.5 2.2 1 0 0 1 1 1 1 Ion channel CaMBD PF02888.16 PVD21467.1 - 1.2e-09 38.2 1.6 2.8e-09 37.0 1.6 1.7 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans PF00520.31 PVD21467.1 - 7.8e-05 22.0 4.2 0.00069 18.9 4.1 2.3 1 1 0 1 1 1 1 Ion transport protein DUF1129 PF06570.11 PVD21467.1 - 0.13 11.7 1.3 0.33 10.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2681 PF10883.8 PVD21467.1 - 0.19 12.2 1.4 0.32 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Hydantoinase_B PF02538.14 PVD21468.1 - 6.6e-214 711.1 0.5 9.2e-214 710.6 0.5 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PVD21468.1 - 1.1e-107 359.6 0.5 2.3e-107 358.6 0.5 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PVD21468.1 - 2.2e-61 206.7 0.5 2.5e-59 200.0 0.0 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region NUDIX PF00293.28 PVD21468.1 - 0.032 14.3 0.0 0.3 11.1 0.0 2.5 3 0 0 3 3 3 0 NUDIX domain Complex1_30kDa PF00329.19 PVD21469.1 - 3.1e-42 144.1 0.0 4.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit adh_short_C2 PF13561.6 PVD21470.1 - 8.8e-19 68.0 0.0 1.6e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD21470.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF2347 PF09804.9 PVD21471.1 - 3.2e-68 230.4 0.0 3.2e-68 230.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Ank_2 PF12796.7 PVD21471.1 - 5.5e-12 46.1 0.1 1.3e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21471.1 - 8e-12 45.4 0.3 6.5e-09 36.2 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SPA PF08616.10 PVD21471.1 - 9.8e-12 44.8 0.1 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Ank_5 PF13857.6 PVD21471.1 - 4.8e-10 39.5 0.1 1.3e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD21471.1 - 2.2e-09 37.3 2.2 1.1e-06 28.8 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Avl9 PF09794.9 PVD21471.1 - 7.3e-09 34.8 0.6 2.6e-05 23.1 0.0 3.2 2 1 0 2 2 2 2 Transport protein Avl9 Ank_3 PF13606.6 PVD21471.1 - 1.1e-08 34.6 0.7 1.1e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L14e PF01929.17 PVD21472.1 - 5.6e-31 106.9 7.9 9.5e-31 106.1 7.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 PVD21472.1 - 0.029 14.3 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 KOW motif FAD-oxidase_C PF02913.19 PVD21473.1 - 2.1e-64 217.6 0.0 3.4e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PVD21473.1 - 1.8e-34 118.5 0.3 2.8e-34 117.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain AP_endonuc_2 PF01261.24 PVD21473.1 - 0.081 12.4 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Laminin_G_2 PF02210.24 PVD21474.1 - 3.9e-12 46.8 0.0 6.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 PVD21474.1 - 7.7e-10 39.1 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain AAA PF00004.29 PVD21475.1 - 5.1e-20 72.2 0.0 9.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PVD21475.1 - 1.5e-13 50.5 0.1 1.6e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 PVD21475.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_16 PF13191.6 PVD21475.1 - 0.00018 21.9 0.6 0.045 14.1 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_17 PF13207.6 PVD21475.1 - 0.0021 18.5 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD21475.1 - 0.01 16.0 0.0 0.081 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD21475.1 - 0.012 15.9 0.1 0.32 11.3 0.1 2.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PVD21475.1 - 0.013 15.4 0.3 5.6 6.8 0.1 2.3 1 1 1 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 PVD21475.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PVD21475.1 - 0.027 15.0 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 PVD21475.1 - 0.033 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain CPT PF07931.12 PVD21475.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.14 PVD21475.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FAM92 PF06730.11 PVD21476.1 - 1.7e-63 214.1 6.0 2.5e-63 213.5 6.0 1.2 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 PVD21476.1 - 6.2e-05 22.7 11.7 0.014 15.0 9.3 3.0 1 1 1 2 2 2 1 Vps5 C terminal like BAR_3 PF16746.5 PVD21476.1 - 0.00036 20.3 11.9 0.0009 19.0 10.7 1.9 1 1 0 1 1 1 1 BAR domain of APPL family TRAF_BIRC3_bd PF16673.5 PVD21476.1 - 0.15 11.8 3.0 2.5 8.0 0.0 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain BAR_3_WASP_bdg PF10456.9 PVD21476.1 - 0.27 10.7 9.4 0.071 12.6 4.0 2.5 2 1 1 3 3 3 0 WASP-binding domain of Sorting nexin protein Peptidase_C58 PF03543.14 PVD21476.1 - 0.28 10.9 5.4 0.088 12.5 1.9 1.9 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen CREPT PF16566.5 PVD21476.1 - 0.32 11.2 0.1 0.32 11.2 0.1 3.5 2 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour TERB2 PF15101.6 PVD21476.1 - 7.9 6.5 10.3 6.6 6.7 3.7 2.6 1 1 2 3 3 3 0 Telomere-associated protein TERB2 FH2 PF02181.23 PVD21477.1 - 6.9e-15 55.0 1.8 7.5e-15 54.9 0.1 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain DEP PF00610.21 PVD21477.1 - 1.6e-06 28.1 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VWA PF00092.28 PVD21481.1 - 2.1e-44 151.8 0.2 2.8e-44 151.4 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWC PF00093.18 PVD21481.1 - 2.3e-27 95.1 619.4 0.0021 18.3 13.9 28.5 29 0 0 29 29 29 25 von Willebrand factor type C domain VWA_2 PF13519.6 PVD21481.1 - 6e-19 68.7 0.0 9.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain ShK PF01549.24 PVD21481.1 - 8.5e-07 29.4 24.8 6.3e-06 26.6 8.8 7.4 7 0 0 7 7 7 3 ShK domain-like VWA_3 PF13768.6 PVD21481.1 - 1.2e-06 28.5 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 PVD21481.1 - 0.0029 17.1 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Copine ShK PF01549.24 PVD21482.1 - 4.5e-06 27.1 43.2 0.00073 20.0 9.3 6.0 5 1 0 5 5 5 3 ShK domain-like VWC PF00093.18 PVD21482.1 - 1e-05 25.7 34.6 7.4e-05 23.0 12.0 6.3 4 1 1 5 5 5 2 von Willebrand factor type C domain SNARE_assoc PF09335.11 PVD21483.1 - 5.8e-14 52.6 5.1 5.8e-14 52.6 5.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0016 PF01169.19 PVD21483.1 - 0.059 13.7 6.9 0.31 11.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Myb_DNA-bind_4 PF13837.6 PVD21484.1 - 4.8e-14 52.5 2.7 1.1e-13 51.4 2.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD21484.1 - 0.00092 19.5 2.4 0.0023 18.2 2.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 PVD21484.1 - 0.003 18.5 3.3 0.003 18.5 3.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD21484.1 - 0.0033 17.5 2.3 0.0085 16.1 2.3 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 PVD21484.1 - 0.18 12.4 3.9 0.18 12.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_4 PF13837.6 PVD21485.1 - 2e-11 44.1 3.0 2e-11 44.1 3.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD21485.1 - 6.2e-05 23.2 1.2 0.00016 21.9 1.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 PVD21485.1 - 9.9e-05 23.3 3.0 9.9e-05 23.3 3.0 1.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD21485.1 - 0.015 15.5 0.6 0.038 14.2 0.6 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD21485.1 - 0.046 13.8 1.9 0.52 10.4 1.4 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain MS_channel PF00924.18 PVD21485.1 - 0.11 12.1 2.7 0.081 12.5 0.3 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel AA_permease_2 PF13520.6 PVD21488.1 - 4e-63 213.7 52.7 1.1e-43 149.7 20.7 3.1 2 1 1 3 3 3 3 Amino acid permease AA_permease PF00324.21 PVD21488.1 - 5.8e-21 74.6 43.1 6.9e-17 61.2 25.3 2.3 2 0 0 2 2 2 2 Amino acid permease Podoplanin PF05808.11 PVD21488.1 - 0.0058 16.8 0.8 2.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Podoplanin GPR_Gpa2_C PF11970.8 PVD21488.1 - 1.9 8.6 5.8 1.6 8.8 0.5 2.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Acid_PPase PF12689.7 PVD21489.1 - 1.1e-42 145.7 0.1 1.6e-42 145.2 0.1 1.2 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 PVD21489.1 - 3.1e-08 33.9 0.2 1.8e-07 31.4 0.0 1.9 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 PVD21489.1 - 1.1e-06 28.6 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 PVD21489.1 - 0.037 13.5 0.1 0.56 9.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) Hydrolase PF00702.26 PVD21489.1 - 0.068 13.4 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD21489.1 - 0.075 13.4 1.5 2.2 8.7 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Thioredoxin_6 PF13848.6 PVD21491.1 - 4.1e-08 33.3 3.8 8.1e-08 32.4 0.2 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 PVD21491.1 - 1.3e-07 31.5 0.2 0.00055 19.9 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin HyaE PF07449.11 PVD21491.1 - 0.00044 20.2 0.2 1 9.3 0.1 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE DUF1843 PF08898.10 PVD21491.1 - 0.021 15.3 0.9 0.095 13.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RRN3 PF05327.11 PVD21491.1 - 0.045 12.3 6.1 0.068 11.7 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4887 PF16228.5 PVD21491.1 - 0.094 12.9 15.3 0.16 12.1 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) CPSF100_C PF13299.6 PVD21491.1 - 1.1 9.4 9.2 2 8.6 9.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2407 PF10302.9 PVD21491.1 - 1.9 9.1 5.1 4.4 7.9 5.1 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RNA_pol_Rpc4 PF05132.14 PVD21491.1 - 2.2 8.7 9.4 4.2 7.8 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 PVD21491.1 - 3.8 6.2 7.1 5.9 5.5 7.1 1.3 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 PVD21491.1 - 4.5 7.0 6.3 9.5 5.9 6.3 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 PVD21491.1 - 5.8 6.6 8.9 9.7 5.9 8.9 1.3 1 0 0 1 1 1 0 Connexin WRNPLPNID PF15017.6 PVD21491.1 - 8.2 7.4 11.5 19 6.2 11.5 1.7 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box ShK PF01549.24 PVD21492.1 - 8.1e-07 29.5 25.0 2.2e-05 24.9 8.4 3.3 3 1 0 3 3 3 2 ShK domain-like VWC PF00093.18 PVD21493.1 - 0.00014 22.1 56.8 0.19 12.1 12.5 3.3 3 0 0 3 3 3 3 von Willebrand factor type C domain START PF01852.19 PVD21493.1 - 0.038 13.4 0.9 4.5 6.6 0.1 2.2 2 0 0 2 2 2 0 START domain VWA PF00092.28 PVD21494.1 - 2.5e-68 229.7 1.5 3.3e-48 164.3 0.2 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD21494.1 - 1.6e-17 64.1 0.0 3.7e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD21494.1 - 3.9e-09 36.6 0.0 1.5e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain ShK PF01549.24 PVD21494.1 - 0.00043 20.8 6.8 0.00043 20.8 6.8 5.4 5 1 0 5 5 5 2 ShK domain-like VWC PF00093.18 PVD21494.1 - 0.016 15.5 13.2 0.016 15.5 13.2 4.7 4 1 0 4 4 4 0 von Willebrand factor type C domain VWA_CoxE PF05762.14 PVD21494.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Alpha_kinase PF02816.18 PVD21495.1 - 2.1e-34 119.3 0.2 1.7e-33 116.3 0.0 2.4 2 0 0 2 2 2 1 Alpha-kinase family DUF559 PF04480.12 PVD21495.1 - 0.076 12.9 0.8 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF559) Fez1 PF06818.15 PVD21496.1 - 2.4e-09 37.9 379.9 0.019 15.4 18.3 18.8 1 1 15 17 17 17 9 Fez1 Tropomyosin PF00261.20 PVD21496.1 - 6.1e-06 25.8 28.1 6.1e-06 25.8 28.1 15.0 3 2 9 14 14 14 5 Tropomyosin Golgin_A5 PF09787.9 PVD21496.1 - 9.6e-05 22.0 415.3 0.022 14.2 18.7 16.9 2 1 13 16 16 16 9 Golgin subfamily A member 5 AAA_13 PF13166.6 PVD21496.1 - 0.00014 20.7 25.1 0.00014 20.7 25.1 12.3 1 1 11 12 12 12 4 AAA domain CALCOCO1 PF07888.11 PVD21496.1 - 0.00018 20.5 22.0 0.00018 20.5 22.0 11.2 1 1 10 11 11 11 2 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 PVD21496.1 - 0.00042 20.6 430.8 0.02 15.1 18.4 19.6 2 1 17 19 19 19 6 Autophagy protein 16 (ATG16) Spc7 PF08317.11 PVD21496.1 - 0.0012 17.8 8.1 0.0012 17.8 8.1 17.4 2 1 15 17 17 17 10 Spc7 kinetochore protein UPF0242 PF06785.11 PVD21496.1 - 0.005 17.0 22.5 0.005 17.0 22.5 19.9 1 1 17 18 18 18 6 Uncharacterised protein family (UPF0242) N-terminus GCSF PF16647.5 PVD21496.1 - 3.9 7.3 7.1 6.6 6.6 0.1 4.4 4 0 0 4 4 4 0 Granulocyte colony-stimulating factor Death PF00531.22 PVD21498.1 - 7.9e-13 48.4 0.2 1.2e-12 47.8 0.2 1.3 1 0 0 1 1 1 1 Death domain G-alpha PF00503.20 PVD21499.1 - 1.3e-22 80.4 0.0 6.4e-18 65.0 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 PVD21499.1 - 0.16 11.4 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 PVD21500.1 - 2.5e-11 44.0 14.3 1.4e-05 25.8 0.6 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21500.1 - 1.6e-05 25.1 2.3 0.058 13.7 0.3 2.9 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD21500.1 - 0.00024 20.2 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Neuralized PF07177.12 PVD21501.1 - 4.9e-39 133.7 0.0 7.1e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Neuralized TRAP_alpha PF03896.16 PVD21502.1 - 2.5e-07 30.2 0.2 2.6e-07 30.1 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit FAD_binding_1 PF00667.20 PVD21503.1 - 6.5e-48 163.2 0.0 9.2e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PVD21503.1 - 5.6e-34 117.4 0.0 9.5e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PVD21503.1 - 2.6e-13 50.6 0.0 5.3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Amidohydro_2 PF04909.14 PVD21503.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Flavodoxin_5 PF12724.7 PVD21503.1 - 0.12 12.6 0.0 1.8 8.8 0.0 2.8 3 1 1 4 4 4 0 Flavodoxin domain Ldl_recept_a PF00057.18 PVD21505.1 - 1.8e-08 34.4 15.0 1.8e-08 34.4 15.0 1.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF998 PF06197.13 PVD21505.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Shadoo PF14999.6 PVD21505.1 - 0.034 14.3 0.0 0.051 13.7 0.0 1.3 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2975 PF11188.8 PVD21505.1 - 0.077 12.9 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4191 PF13829.6 PVD21505.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CUB PF00431.20 PVD21506.1 - 9e-22 77.5 0.0 4.5e-06 27.0 0.0 5.4 5 0 0 5 5 5 4 CUB domain RXLR_WY PF18634.1 PVD21506.1 - 0.014 15.3 1.6 0.84 9.6 0.7 2.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain Transglut_core PF01841.19 PVD21507.1 - 9.5e-05 22.8 0.9 0.00051 20.5 0.0 2.6 3 0 0 3 3 3 1 Transglutaminase-like superfamily MscS_porin PF12795.7 PVD21507.1 - 0.0074 15.9 4.5 0.015 14.8 4.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain VIR_N PF15912.5 PVD21507.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal ODAM PF15424.6 PVD21507.1 - 0.26 10.9 3.3 0.3 10.6 0.0 2.3 3 0 0 3 3 3 0 Odontogenic ameloblast-associated family BRCC36_C PF18110.1 PVD21507.1 - 3.2 8.0 5.2 0.96 9.7 0.9 2.3 3 0 0 3 3 3 0 BRCC36 C-terminal helical domain WD40 PF00400.32 PVD21508.1 - 4e-11 43.3 16.1 0.00056 20.7 0.5 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21508.1 - 1.6e-06 28.3 0.0 0.02 15.2 0.0 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 PVD21508.1 - 0.0012 18.5 0.1 0.0024 17.5 0.1 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain HAUS6_N PF14661.6 PVD21508.1 - 0.035 13.7 0.4 0.057 13.0 0.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Suppressor_APC PF11414.8 PVD21508.1 - 0.39 10.8 10.6 0.89 9.7 10.6 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein UPF0242 PF06785.11 PVD21508.1 - 0.73 9.9 8.8 1.3 9.1 8.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 PVD21508.1 - 3.3 8.1 11.2 5.6 7.3 11.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Abhydrolase_3 PF07859.13 PVD21509.1 - 4.1e-10 39.9 0.0 1.1e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 PVD21509.1 - 6.4e-05 22.7 0.0 0.001 18.8 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 PVD21509.1 - 0.00031 20.4 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 PVD21509.1 - 0.00096 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PVD21509.1 - 0.0017 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 PVD21509.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 PVD21509.1 - 0.013 16.1 0.0 0.022 15.4 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.28 PVD21509.1 - 0.033 13.1 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Lipase_3 PF01764.25 PVD21509.1 - 0.084 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 PVD21509.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Sad1_UNC PF07738.13 PVD21510.1 - 6.3e-24 84.5 0.0 2.3e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal SlyX PF04102.12 PVD21510.1 - 0.096 13.3 5.6 10 6.8 3.4 3.1 1 1 1 2 2 2 0 SlyX PMC2NT PF08066.12 PVD21510.1 - 0.26 12.0 4.6 0.47 11.2 3.0 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Chordopox_L2 PF05803.12 PVD21510.1 - 1.4 8.8 4.6 3.9 7.4 0.5 2.4 2 0 0 2 2 2 0 Chordopoxvirus L2 protein DUF16 PF01519.16 PVD21510.1 - 2.1 8.9 8.6 1.2 9.7 3.5 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 HSP20 PF00011.21 PVD21512.1 - 8.5e-13 48.3 0.0 2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RRM_1 PF00076.22 PVD21512.1 - 1.9e-12 46.8 0.0 3.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArsA_HSP20 PF17886.1 PVD21512.1 - 0.019 14.5 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA HSP20 PF00011.21 PVD21513.1 - 1.2e-14 54.3 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD21513.1 - 0.0041 16.6 0.0 0.0094 15.5 0.0 1.6 1 1 1 2 2 2 1 HSP20-like domain found in ArsA ADK PF00406.22 PVD21515.1 - 3.1e-190 624.6 10.6 1.4e-51 174.6 0.1 6.3 5 1 1 6 6 6 6 Adenylate kinase AAA_17 PF13207.6 PVD21515.1 - 5.8e-138 454.2 12.9 5.8e-36 123.9 0.1 6.4 5 1 1 6 6 6 6 AAA domain AAA_18 PF13238.6 PVD21515.1 - 5.3e-34 117.6 3.2 1.5e-07 32.0 0.0 6.7 5 1 1 6 6 6 5 AAA domain Sec16_C PF12931.7 PVD21515.1 - 6.4e-33 114.7 1.6 4.5e-26 92.2 0.1 2.5 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 AAA_33 PF13671.6 PVD21515.1 - 9.7e-30 103.6 0.3 6.3e-06 26.4 0.0 6.7 5 1 1 6 6 6 4 AAA domain AAA_19 PF13245.6 PVD21515.1 - 1.1e-09 38.8 5.1 0.2 12.0 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 PVD21515.1 - 1.9e-08 34.8 0.5 1.8 9.0 0.0 5.7 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 PVD21515.1 - 2.1e-08 34.3 0.9 0.45 10.4 0.0 5.3 5 0 0 5 5 5 2 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 PVD21515.1 - 8.9e-08 32.0 21.0 0.0057 16.3 0.3 8.6 7 3 1 8 8 8 1 Thymidylate kinase Zeta_toxin PF06414.12 PVD21515.1 - 4.9e-07 29.2 6.4 2 7.6 0.0 5.6 5 0 0 5 5 5 1 Zeta toxin Cytidylate_kin PF02224.18 PVD21515.1 - 3.9e-06 26.8 1.9 2.1 8.1 0.0 4.9 5 0 0 5 5 5 2 Cytidylate kinase AAA_22 PF13401.6 PVD21515.1 - 5.3e-06 26.7 4.3 0.82 9.9 0.0 5.0 5 0 0 5 5 4 1 AAA domain Sec16 PF12932.7 PVD21515.1 - 4.2e-05 24.1 0.0 0.00014 22.5 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region AAA_28 PF13521.6 PVD21515.1 - 7.5e-05 23.0 10.0 1.3 9.3 0.0 6.0 7 0 0 7 7 5 1 AAA domain ABC_tran PF00005.27 PVD21515.1 - 0.00048 20.6 8.3 1.3 9.6 0.0 6.1 6 0 0 6 6 5 1 ABC transporter AAA_16 PF13191.6 PVD21515.1 - 0.00088 19.7 0.3 24 5.3 0.0 5.5 5 0 0 5 5 5 0 AAA ATPase domain NB-ARC PF00931.22 PVD21515.1 - 0.0012 18.1 2.1 13 4.9 0.0 4.4 4 0 0 4 4 4 0 NB-ARC domain Hydin_ADK PF17213.3 PVD21515.1 - 0.032 14.5 22.2 6.9 6.9 0.0 7.7 7 0 0 7 7 5 0 Hydin Adenylate kinase-like domain Sigma54_activ_2 PF14532.6 PVD21515.1 - 0.05 13.7 0.3 5.9 7.0 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain RraA-like PF03737.15 PVD21515.1 - 0.061 13.5 0.0 0.94 9.6 0.0 2.8 3 0 0 3 3 3 0 Aldolase/RraA NTPase_1 PF03266.15 PVD21515.1 - 0.1 12.5 9.9 20 5.1 0.1 5.6 6 0 0 6 6 6 0 NTPase T2SSE PF00437.20 PVD21515.1 - 0.11 11.6 0.7 32 3.4 0.0 3.8 4 0 0 4 4 4 0 Type II/IV secretion system protein Sec5 PF15469.6 PVD21515.1 - 0.15 11.8 2.9 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Exocyst complex component Sec5 AAA_24 PF13479.6 PVD21515.1 - 0.27 10.9 5.7 23 4.6 0.1 4.7 5 0 0 5 5 5 0 AAA domain ATPase PF06745.13 PVD21515.1 - 0.31 10.4 5.4 29 3.9 0.0 4.4 5 0 0 5 5 4 0 KaiC CoaE PF01121.20 PVD21515.1 - 0.32 10.7 1.3 79 2.8 0.0 4.3 4 0 0 4 4 4 0 Dephospho-CoA kinase RNA_helicase PF00910.22 PVD21515.1 - 1.3 9.4 5.6 20 5.6 0.1 4.6 4 0 0 4 4 4 0 RNA helicase SRP54 PF00448.22 PVD21515.1 - 7.5 6.1 7.6 62 3.1 0.0 4.5 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain Peptidase_C13 PF01650.18 PVD21516.1 - 8.2e-46 156.6 0.0 1.5e-45 155.7 0.0 1.3 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.22 PVD21516.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Caspase domain CBM_5_12_2 PF14600.6 PVD21516.1 - 0.16 11.9 1.7 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Cellulose-binding domain Ras PF00071.22 PVD21517.1 - 4.6e-40 136.9 0.0 5.8e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD21517.1 - 2.6e-21 76.1 0.0 4.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD21517.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD21517.1 - 0.003 17.1 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD21517.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Tektin PF03148.14 PVD21518.1 - 2e-31 109.1 11.8 2.7e-31 108.7 11.8 1.1 1 0 0 1 1 1 1 Tektin family Vps5 PF09325.10 PVD21518.1 - 0.0011 18.6 0.5 0.0032 17.0 0.5 1.7 1 0 0 1 1 1 1 Vps5 C terminal like HOIP-UBA PF16678.5 PVD21518.1 - 0.034 14.1 0.2 0.22 11.5 0.0 2.3 2 1 0 2 2 2 0 HOIP UBA domain pair Fib_alpha PF08702.10 PVD21518.1 - 0.8 9.9 4.0 7.3 6.8 1.3 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 PVD21518.1 - 0.99 9.9 7.3 0.72 10.4 4.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 PVD21518.1 - 1.8 8.5 10.3 1.7 8.7 0.5 2.8 3 0 0 3 3 3 0 Prefoldin subunit Trans_reg_C PF00486.28 PVD21518.1 - 2.2 8.4 4.8 8.2 6.6 0.5 3.1 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal DUF5082 PF16888.5 PVD21518.1 - 5.1 7.4 13.6 8.6 6.7 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Phostensin PF13914.6 PVD21519.1 - 0.00052 20.7 0.0 0.00052 20.7 0.0 3.1 2 1 0 2 2 2 1 Phostensin PP1-binding and SH3-binding region NAP PF00956.18 PVD21520.1 - 2.1e-37 128.8 13.7 3.8e-34 118.1 5.6 3.4 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Uds1 PF15456.6 PVD21520.1 - 0.23 11.6 4.9 0.55 10.4 4.9 1.7 1 0 0 1 1 1 0 Up-regulated During Septation SseC PF04888.12 PVD21520.1 - 1 8.9 5.1 1.5 8.4 5.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Dynamin_N PF00350.23 PVD21520.1 - 3.1 7.8 5.6 0.42 10.7 1.1 1.9 2 1 0 2 2 2 0 Dynamin family Ank_2 PF12796.7 PVD21521.1 - 2.2e-22 79.4 1.9 4.3e-09 36.8 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21521.1 - 7.4e-18 64.7 3.1 0.00085 19.8 0.0 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD21521.1 - 7.3e-17 61.0 13.2 0.00011 22.5 0.2 5.9 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD21521.1 - 1.4e-13 50.8 0.5 6.8e-08 32.6 0.2 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD21521.1 - 3.7e-10 39.1 5.3 0.078 13.6 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat SOCS_box PF07525.16 PVD21521.1 - 5.1e-08 33.1 6.5 6e-08 32.9 5.1 2.0 2 0 0 2 2 2 1 SOCS box DUF4612 PF15389.6 PVD21524.1 - 2.2e-12 48.1 2.6 2e-11 45.0 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4612) GRP PF07172.11 PVD21524.1 - 1.8 9.3 14.6 1.2 9.9 12.9 1.5 1 1 0 1 1 1 0 Glycine rich protein family I-set PF07679.16 PVD21525.1 - 0 1474.2 0.0 4.6e-18 65.1 0.0 28.4 28 0 0 28 28 28 28 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21525.1 - 0 1323.8 49.3 2.5e-15 56.8 0.0 28.6 28 0 0 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 PVD21525.1 - 1.2e-294 951.6 14.6 8.6e-11 42.0 0.0 29.1 29 0 0 29 29 29 28 Immunoglobulin domain ig PF00047.25 PVD21525.1 - 3.8e-248 802.6 0.0 2e-10 40.7 0.0 28.6 28 0 0 28 28 28 28 Immunoglobulin domain V-set PF07686.17 PVD21525.1 - 1.2e-112 369.7 65.3 7e-05 23.0 0.1 45.2 31 18 3 34 34 34 27 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD21525.1 - 4.6e-72 238.1 31.5 0.00087 19.3 0.1 27.4 27 0 0 27 27 27 16 CD80-like C2-set immunoglobulin domain TSP_1 PF00090.19 PVD21525.1 - 5.6e-67 221.8 104.5 9.8e-13 48.1 5.7 8.1 7 0 0 7 7 7 6 Thrombospondin type 1 domain EGF_CA PF07645.15 PVD21525.1 - 1.8e-63 210.5 113.0 1.1e-10 41.5 7.7 10.4 10 0 0 10 10 9 8 Calcium-binding EGF domain Ig_5 PF16681.5 PVD21525.1 - 6.4e-55 183.5 0.0 0.069 13.6 0.0 27.0 27 1 0 27 27 26 7 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain cEGF PF12662.7 PVD21525.1 - 2.2e-45 152.2 60.0 8.4e-11 41.6 1.8 9.2 8 0 0 8 8 8 7 Complement Clr-like EGF-like G2F PF07474.12 PVD21525.1 - 1.1e-42 146.0 0.0 2.3e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 G2F domain Ig_6 PF18452.1 PVD21525.1 - 2.4e-42 142.3 0.0 0.18 11.4 0.0 24.3 29 0 0 29 29 27 9 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21525.1 - 1.3e-31 108.5 8.3 1.4 9.0 0.0 23.0 26 0 0 26 26 25 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 PVD21525.1 - 1.3e-24 86.4 9.1 2.6 8.5 0.0 19.5 21 0 0 21 21 21 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 PVD21525.1 - 1.3e-22 80.0 0.0 0.0094 16.1 0.0 14.4 17 0 0 17 17 15 2 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 PVD21525.1 - 4.7e-22 77.8 2.4 1.1 9.4 0.0 19.2 22 1 1 23 23 20 1 C17orf99 Ig domain FXa_inhibition PF14670.6 PVD21525.1 - 9.2e-20 70.6 128.4 1.8e-08 34.5 10.1 10.6 9 1 1 10 10 9 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD21525.1 - 6.7e-14 51.9 107.1 0.00011 22.4 6.4 10.6 9 0 0 9 9 9 5 EGF-like domain BiPBP_C PF06832.12 PVD21525.1 - 4e-11 42.8 0.5 4.8 7.3 0.0 11.6 12 0 0 12 12 12 1 Penicillin-Binding Protein C-terminus Family C2-set PF05790.15 PVD21525.1 - 7.5e-10 38.9 1.1 15 5.9 0.0 14.7 20 0 0 20 20 18 0 Immunoglobulin C2-set domain EGF_3 PF12947.7 PVD21525.1 - 6.7e-08 32.6 101.0 0.0067 16.6 9.7 9.6 9 0 0 9 9 8 6 EGF domain hEGF PF12661.7 PVD21525.1 - 0.00014 22.3 83.0 0.22 12.2 8.3 11.3 9 0 0 9 9 8 5 Human growth factor-like EGF Alpha_adaptinC2 PF02883.20 PVD21525.1 - 0.00068 19.9 0.0 1.9 8.8 0.0 4.1 3 0 0 3 3 2 1 Adaptin C-terminal domain DUF11 PF01345.18 PVD21525.1 - 2.1 8.7 20.7 9.9 6.5 0.4 8.4 9 0 0 9 9 8 0 Domain of unknown function DUF11 MULE PF10551.9 PVD21527.1 - 1.9e-13 50.6 0.1 4.9e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 PVD21527.1 - 6.9e-10 38.9 1.2 1.6e-09 37.7 1.2 1.7 1 0 0 1 1 1 1 FLYWCH zinc finger domain Transposase_mut PF00872.18 PVD21527.1 - 0.022 13.6 0.1 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Transposase, Mutator family NTF2 PF02136.20 PVD21527.1 - 0.088 13.4 0.2 12 6.5 0.0 3.2 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain dsrm PF00035.26 PVD21528.1 - 2.3e-14 53.8 1.1 0.00088 19.9 0.2 4.7 4 0 0 4 4 4 4 Double-stranded RNA binding motif Aminotran_1_2 PF00155.21 PVD21529.1 - 1.6e-49 169.1 0.0 1.8e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PVD21529.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PVD21529.1 - 0.0038 15.8 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.7 PVD21530.1 - 8.4e-10 38.4 3.5 2.5e-09 36.9 3.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD21530.1 - 1.4e-07 31.2 2.1 3.2e-07 30.1 0.8 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 PVD21530.1 - 0.0001 22.6 11.1 0.025 15.0 1.9 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD21530.1 - 0.0011 18.7 8.3 0.16 11.7 0.5 4.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 PVD21530.1 - 0.0028 17.6 13.2 14 6.1 0.5 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 PVD21530.1 - 0.13 12.9 9.9 5.4 8.0 0.8 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat RAMP4 PF06624.12 PVD21530.1 - 0.62 10.2 1.8 0.78 9.8 0.6 1.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Dsh_C PF12316.8 PVD21530.1 - 0.72 10.2 5.9 1.1 9.6 5.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Cg6151-P PF10233.9 PVD21531.1 - 1.1e-22 80.5 6.9 1.3e-22 80.2 6.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 PVD21531.1 - 0.0036 17.0 0.2 0.0049 16.6 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 ABC_tran PF00005.27 PVD21532.1 - 6.3e-46 156.3 13.1 6.5e-24 85.0 0.0 4.2 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 PVD21532.1 - 1.4e-17 64.4 8.4 1.6e-05 24.9 0.0 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD21532.1 - 3.5e-13 49.5 2.1 0.0003 20.3 0.0 4.8 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 PVD21532.1 - 5.1e-07 29.6 14.0 5.1e-07 29.6 14.0 4.5 5 1 1 6 6 2 1 ABC transporter AAA_16 PF13191.6 PVD21532.1 - 5.5e-07 30.1 0.1 0.031 14.6 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 PVD21532.1 - 7.2e-07 29.6 0.0 0.04 14.2 0.0 3.6 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 PVD21532.1 - 1.2e-06 28.9 0.3 0.015 15.6 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 PVD21532.1 - 1.9e-06 28.3 0.3 0.014 15.9 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PVD21532.1 - 2e-06 27.5 2.0 0.0034 17.1 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 PVD21532.1 - 2.2e-06 27.5 0.0 0.016 14.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 PVD21532.1 - 7.9e-06 25.9 0.1 0.0054 16.8 0.0 3.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 PVD21532.1 - 1.6e-05 24.9 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 PVD21532.1 - 2.4e-05 24.2 25.9 0.01 15.6 0.0 4.3 2 1 1 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 PVD21532.1 - 2.8e-05 24.1 0.5 0.38 10.8 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 PVD21532.1 - 4.8e-05 23.2 3.3 0.26 11.0 0.0 3.6 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 PVD21532.1 - 5.5e-05 23.5 0.0 0.47 10.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase NB-ARC PF00931.22 PVD21532.1 - 5.8e-05 22.4 0.2 0.3 10.3 0.0 3.1 3 0 0 3 3 2 2 NB-ARC domain NTPase_1 PF03266.15 PVD21532.1 - 7e-05 22.8 0.3 0.36 10.7 0.0 3.0 3 0 0 3 3 2 2 NTPase RsgA_GTPase PF03193.16 PVD21532.1 - 0.00016 21.6 0.0 0.0025 17.8 0.0 3.5 4 0 0 4 4 2 2 RsgA GTPase AAA_23 PF13476.6 PVD21532.1 - 0.00042 20.9 0.0 0.013 16.0 0.0 5.8 5 1 0 5 5 4 2 AAA domain AAA_7 PF12775.7 PVD21532.1 - 0.00057 19.4 0.1 1.1 8.7 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region cobW PF02492.19 PVD21532.1 - 0.0007 19.2 0.1 0.57 9.8 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 PVD21532.1 - 0.0012 19.1 1.0 1.7 8.9 0.0 3.5 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 PVD21532.1 - 0.0013 18.9 4.8 0.37 11.0 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 PVD21532.1 - 0.0015 18.6 0.1 2.4 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PVD21532.1 - 0.0048 16.3 0.0 7 6.0 0.0 3.4 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PVD21532.1 - 0.0049 16.6 0.1 4.1 7.1 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein SRP54 PF00448.22 PVD21532.1 - 0.0074 15.9 0.0 1.7 8.2 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 PVD21532.1 - 0.012 15.2 0.0 5.4 6.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 PVD21532.1 - 0.063 13.3 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 PVD21532.1 - 0.078 12.7 0.0 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 PVD21532.1 - 0.091 12.7 0.0 0.091 12.7 0.0 4.5 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 PVD21532.1 - 0.097 13.0 1.5 3.1 8.1 0.2 3.2 2 2 0 2 2 2 0 AAA domain RuvB_N PF05496.12 PVD21532.1 - 0.13 12.0 0.0 26 4.5 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SbcCD_C PF13558.6 PVD21532.1 - 0.16 12.2 1.9 4.8 7.5 0.1 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 PVD21532.1 - 0.92 8.4 5.9 2.9 6.8 0.0 3.6 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 PVD21532.1 - 0.92 9.3 5.9 13 5.6 0.0 3.7 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 PVD21532.1 - 1.9 8.5 0.0 1.9 8.5 0.0 4.7 3 1 2 5 5 3 0 Helicase HerA, central domain AAA_18 PF13238.6 PVD21532.1 - 2.3 8.8 19.1 0.34 11.5 0.1 4.9 5 2 1 6 6 4 0 AAA domain DUF3987 PF13148.6 PVD21532.1 - 7 5.6 0.0 7 5.6 0.0 4.0 3 1 1 4 4 3 0 Protein of unknown function (DUF3987) GTP_EFTU PF00009.27 PVD21532.1 - 7.5 6.0 10.7 4.2 6.9 0.0 4.1 3 2 1 4 4 3 0 Elongation factor Tu GTP binding domain Acetyltransf_16 PF05301.11 PVD21533.1 - 8.4e-68 227.6 0.0 1.4e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Proho_convert PF12177.8 PVD21533.1 - 0.034 14.1 0.2 0.088 12.8 0.2 1.7 1 0 0 1 1 1 0 Prohormone convertase enzyme MMR_HSR1 PF01926.23 PVD21534.1 - 3.5e-14 52.8 0.0 2e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD21534.1 - 2.4e-05 23.9 0.2 9.2e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD21534.1 - 0.017 15.0 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 PVD21534.1 - 1.5 8.8 5.6 0.26 11.3 0.4 2.3 2 1 1 3 3 3 0 Dynamin family DUF4279 PF14106.6 PVD21535.1 - 2.1 8.6 7.5 2.4 8.4 0.1 3.7 2 1 3 5 5 5 0 Domain of unknown function (DUF4279) CPP1-like PF11833.8 PVD21535.1 - 2.5 7.7 11.6 0.17 11.5 4.6 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AAA_31 PF13614.6 PVD21535.1 - 8.4 6.3 10.2 2 8.3 0.7 2.9 2 1 1 3 3 3 0 AAA domain DUF4483 PF14825.6 PVD21536.1 - 7e-37 126.6 0.0 1e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) RVT_1 PF00078.27 PVD21538.1 - 6.4e-34 117.4 0.0 9.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_2 PF08356.12 PVD21538.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 EF hand associated Exo_endo_phos PF03372.23 PVD21539.1 - 2.7e-05 23.8 0.1 9.2e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NSP2-B_epitope PF14757.6 PVD21539.1 - 0.061 13.0 2.1 0.13 12.0 2.1 1.5 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF2408 PF10303.9 PVD21539.1 - 0.5 10.9 1.8 1.7 9.2 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CxC3 PF18804.1 PVD21540.1 - 9.7e-19 67.3 3.3 2e-08 34.1 0.2 2.6 2 0 0 2 2 2 2 CxC3 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 PVD21540.1 - 3.5e-07 30.3 5.7 0.0025 17.9 0.3 2.4 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases PDZ_3 PF17815.1 PVD21540.1 - 0.013 15.3 0.0 0.054 13.4 0.0 2.0 1 0 0 1 1 1 0 PDZ domain DUF5618 PF18498.1 PVD21540.1 - 0.028 14.6 0.2 15 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5618) Imm74 PF15603.6 PVD21540.1 - 0.14 12.4 3.7 0.85 9.9 0.3 3.1 2 0 0 2 2 2 0 Immunity protein 74 Glyco_hydro_8 PF01270.17 PVD21540.1 - 0.93 8.2 2.9 3.1 6.5 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 8 DUF5344 PF17279.2 PVD21540.1 - 1.3 9.6 12.3 1.8 9.2 4.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5344) AIDA PF16168.5 PVD21540.1 - 1.4 9.0 5.2 2.6 8.2 0.4 3.1 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk DUF4402 PF14352.6 PVD21540.1 - 5.3 7.7 14.3 45 4.7 4.3 4.1 2 2 1 4 4 4 0 Domain of unknown function (DUF4402) DUF2993 PF11209.8 PVD21540.1 - 7.4 6.8 8.6 17 5.6 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2993) DUF3244 PF11589.8 PVD21540.1 - 7.6 6.7 6.9 6.5 6.9 0.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3244) DUF1647 PF07801.11 PVD21541.1 - 0.018 14.8 0.1 0.035 13.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) PseudoU_synth_2 PF00849.22 PVD21542.1 - 0.083 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase C1q PF00386.21 PVD21543.1 - 4.2e-14 52.8 0.4 1.5e-13 51.1 0.2 2.0 1 1 1 2 2 2 1 C1q domain C1q PF00386.21 PVD21544.1 - 2.7e-13 50.2 0.2 4.5e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 C1q domain Chordopox_A30L PF06015.12 PVD21544.1 - 0.0023 17.7 1.9 0.61 9.9 0.1 2.3 2 0 0 2 2 2 2 Chordopoxvirus A30L protein ABC_tran_CTD PF16326.5 PVD21544.1 - 0.011 15.9 13.0 0.97 9.7 6.3 3.5 3 1 0 3 3 3 0 ABC transporter C-terminal domain PriC PF07445.12 PVD21544.1 - 0.015 15.2 3.9 0.84 9.5 1.0 2.5 2 1 1 3 3 3 0 Primosomal replication protein priC NPV_P10 PF05531.12 PVD21544.1 - 0.021 15.3 1.8 11 6.6 0.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4094 PF13334.6 PVD21544.1 - 0.026 14.9 5.7 0.94 9.9 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4164 PF13747.6 PVD21544.1 - 0.053 13.8 13.0 0.42 10.9 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF16 PF01519.16 PVD21544.1 - 0.061 13.8 3.3 3.4 8.2 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3584 PF12128.8 PVD21544.1 - 0.095 10.2 4.4 0.12 9.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliD_N PF02465.18 PVD21544.1 - 0.14 12.9 5.4 7.9 7.3 1.4 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF5485 PF17586.2 PVD21544.1 - 0.14 12.5 1.1 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5485) Lambda_tail_I PF06805.12 PVD21544.1 - 0.14 12.5 0.1 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I Allexi_40kDa PF05549.11 PVD21544.1 - 0.25 10.8 4.9 1.2 8.5 0.8 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein MAD PF05557.13 PVD21544.1 - 0.49 8.7 9.6 1 7.6 9.6 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein Spectrin PF00435.21 PVD21544.1 - 0.55 10.7 7.1 9.8 6.7 1.5 3.0 3 0 0 3 3 3 0 Spectrin repeat AAA_13 PF13166.6 PVD21544.1 - 0.94 8.0 8.4 3.4 6.2 3.4 2.0 1 1 0 2 2 2 0 AAA domain OmpH PF03938.14 PVD21544.1 - 0.98 9.8 7.9 3.3 8.0 1.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 PVD21544.1 - 1 8.1 9.3 1.7 7.4 9.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein BMFP PF04380.13 PVD21544.1 - 2.1 8.9 11.3 3.9 8.0 0.3 3.8 4 0 0 4 4 4 0 Membrane fusogenic activity Histone_HNS PF00816.21 PVD21544.1 - 5.8 7.8 6.5 23 5.9 3.3 2.3 2 0 0 2 2 2 0 H-NS histone family Lebercilin PF15619.6 PVD21544.1 - 8.1 6.0 13.6 16 5.1 5.3 2.2 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PhoH PF02562.16 PVD21545.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 PVD21545.1 - 0.0002 21.4 1.4 0.0035 17.4 1.4 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 PVD21545.1 - 0.0021 17.3 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase T2SSE PF00437.20 PVD21545.1 - 0.0042 16.2 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CbiA PF01656.23 PVD21545.1 - 0.0046 17.0 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 PVD21545.1 - 0.013 15.5 0.2 0.3 11.1 0.2 2.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD21545.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD21545.1 - 0.042 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PVD21545.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 PVD21545.1 - 0.12 11.5 1.3 0.22 10.6 0.2 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 PVD21545.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 PVD21545.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 C1q PF00386.21 PVD21546.1 - 3.4e-15 56.4 1.2 7.3e-15 55.3 1.2 1.6 1 0 0 1 1 1 1 C1q domain PA14 PF07691.12 PVD21546.1 - 0.0012 18.7 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 PA14 domain BLOC1_2 PF10046.9 PVD21546.1 - 0.0016 18.7 1.1 0.096 13.0 0.2 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 PVD21546.1 - 0.022 15.2 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 PVD21546.1 - 0.024 14.9 0.2 0.024 14.9 0.2 2.4 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HSBP1 PF06825.12 PVD21546.1 - 0.029 14.2 0.1 7.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 NPV_P10 PF05531.12 PVD21546.1 - 0.035 14.6 4.3 0.12 12.8 1.3 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BclA_C PF18573.1 PVD21546.1 - 0.049 13.6 7.9 0.025 14.5 2.5 2.2 2 0 0 2 2 2 0 BclA C-terminal domain FlaC_arch PF05377.11 PVD21546.1 - 0.11 12.9 0.4 8.7 6.8 0.2 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 PVD21546.1 - 0.16 12.2 0.6 1.9 8.8 0.1 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 PVD21546.1 - 0.18 11.8 1.0 0.59 10.2 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Aminotran_5 PF00266.19 PVD21547.1 - 3.6e-25 88.7 0.0 5.1e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 PVD21547.1 - 1.3e-09 37.7 0.0 2.4e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PVD21547.1 - 1.1e-06 27.4 0.0 1.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PVD21547.1 - 1.4e-05 24.6 2.0 0.00015 21.2 2.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 PVD21547.1 - 0.066 11.8 0.0 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 PVD21549.1 - 3.4e-27 95.4 0.0 4.7e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 PVD21549.1 - 1.5e-09 37.5 0.1 4.9e-09 35.8 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PVD21549.1 - 8.9e-07 27.8 0.0 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PVD21549.1 - 7.5e-05 22.2 1.8 0.00039 19.8 1.8 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 PVD21549.1 - 0.0075 14.9 0.0 0.0098 14.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Peptidase_C107 PF17222.3 PVD21549.1 - 0.078 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 E1_DerP2_DerF2 PF02221.15 PVD21550.1 - 2.4e-06 28.0 0.5 3.4e-06 27.5 0.1 1.4 2 0 0 2 2 2 1 ML domain Tubulin PF00091.25 PVD21551.1 - 1.7e-68 230.7 0.0 2.7e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD21551.1 - 3.1e-43 146.9 0.1 4.9e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PVD21551.1 - 2.9e-05 24.4 0.0 7.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PVD21551.1 - 0.0066 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PVD21551.1 - 0.016 14.4 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 PVD21552.1 - 1.7e-69 234.0 0.0 2.8e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD21552.1 - 2.2e-43 147.4 0.1 3.4e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PVD21552.1 - 1.3e-05 25.4 0.0 3.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PVD21552.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PVD21552.1 - 0.013 14.7 0.1 0.03 13.5 0.0 1.6 2 0 0 2 2 2 0 Tubulin like FWWh PF14922.6 PVD21552.1 - 0.13 12.2 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function Abhydrolase_1 PF00561.20 PVD21553.1 - 1.7e-41 142.6 0.0 2.3e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PVD21553.1 - 6.7e-05 22.6 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 PVD21553.1 - 0.0046 16.5 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2920 PF11144.8 PVD21553.1 - 0.024 13.9 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 PVD21553.1 - 0.026 15.1 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD21553.1 - 0.12 11.6 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 THAP PF05485.12 PVD21555.1 - 5.8e-05 23.9 1.0 0.0005 20.9 0.0 2.9 3 0 0 3 3 3 1 THAP domain DUF4519 PF15012.6 PVD21555.1 - 8.6 6.6 9.8 0.11 12.7 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Ig_3 PF13927.6 PVD21556.1 - 0.0054 17.3 1.6 0.056 14.0 1.6 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD21556.1 - 0.084 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain ADD_ATRX PF17981.1 PVD21558.1 - 0.03 14.2 0.2 0.089 12.7 0.2 1.8 1 0 0 1 1 1 0 Cysteine Rich ADD domain UPF0102 PF02021.17 PVD21559.1 - 0.0071 16.6 0.3 0.017 15.3 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 ResIII PF04851.15 PVD21561.1 - 0.00022 21.3 0.8 0.0029 17.6 0.8 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 PVD21561.1 - 0.00032 20.2 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_14 PF13173.6 PVD21561.1 - 0.0055 16.7 0.2 0.26 11.3 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD21561.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PVD21561.1 - 0.022 14.5 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.14 PVD21561.1 - 0.03 13.5 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 PVD21561.1 - 0.034 14.4 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PVD21561.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein BRCA-2_helical PF09169.10 PVD21562.1 - 2.9e-49 167.3 0.0 6.4e-49 166.2 0.0 1.6 1 0 0 1 1 1 1 BRCA2, helical BRCA-2_OB1 PF09103.10 PVD21562.1 - 2.9e-34 117.7 0.0 7e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.10 PVD21562.1 - 1.3e-10 41.3 1.5 1.3e-10 41.3 1.5 1.9 2 0 0 2 2 2 1 Tower BRCA-2_OB3 PF09104.10 PVD21562.1 - 6.7e-10 38.8 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 RVT_1 PF00078.27 PVD21563.1 - 6.1e-45 153.4 0.1 1.2e-44 152.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C1q PF00386.21 PVD21563.1 - 4.8e-11 43.0 0.3 1.2e-10 41.7 0.3 1.6 1 0 0 1 1 1 1 C1q domain Exo_endo_phos PF03372.23 PVD21563.1 - 0.00025 20.7 0.0 0.0008 19.0 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD21563.1 - 0.52 10.2 6.6 0.15 11.9 0.5 3.3 3 1 0 3 3 3 0 Endonuclease-reverse transcriptase Insulin PF00049.18 PVD21564.1 - 0.32 12.0 4.8 44 5.2 0.1 3.2 2 1 1 3 3 3 0 Insulin/IGF/Relaxin family C1q PF00386.21 PVD21566.1 - 1.5e-14 54.3 0.2 2.2e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD21566.1 - 0.0096 15.8 1.6 0.014 15.3 1.6 1.2 1 0 0 1 1 1 1 BclA C-terminal domain LRAT PF04970.13 PVD21567.1 - 8.2e-30 103.7 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD21567.1 - 0.00076 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Sulf_transp PF04143.14 PVD21567.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Sulphur transport Cupin_1 PF00190.22 PVD21567.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupin C1q PF00386.21 PVD21568.1 - 1.6e-17 63.9 0.2 2.1e-17 63.5 0.2 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD21568.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 BclA C-terminal domain PA14 PF07691.12 PVD21568.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 PA14 domain Lipocalin_7 PF14651.6 PVD21569.1 - 6.3e-05 22.9 0.7 7.5e-05 22.7 0.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family IL12 PF03039.14 PVD21569.1 - 0.046 13.0 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit LRAT PF04970.13 PVD21570.1 - 3.9e-24 85.4 0.3 5.3e-24 84.9 0.3 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 PVD21570.1 - 0.0057 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Gram_pos_anchor PF00746.21 PVD21570.1 - 0.17 11.8 0.5 0.31 11.0 0.5 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LRAT PF04970.13 PVD21571.1 - 1.7e-11 44.5 0.1 5.6e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Lecithin retinol acyltransferase C1q PF00386.21 PVD21572.1 - 6.3e-15 55.5 0.2 1e-14 54.9 0.2 1.3 1 0 0 1 1 1 1 C1q domain Baculo_PEP_C PF04513.12 PVD21572.1 - 9.9e-06 25.6 1.4 1.5e-05 25.1 1.4 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CNDH2_N PF06278.11 PVD21572.1 - 0.0013 18.9 0.2 0.093 12.9 0.2 2.5 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal BclA_C PF18573.1 PVD21572.1 - 0.002 18.0 1.0 0.002 18.0 1.0 1.7 2 0 0 2 2 2 1 BclA C-terminal domain Nup54 PF13874.6 PVD21572.1 - 0.013 15.6 1.7 0.019 15.1 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 OmpH PF03938.14 PVD21572.1 - 0.016 15.5 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 PVD21572.1 - 0.02 15.3 0.9 4.4 7.7 0.1 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 PVD21572.1 - 0.024 14.1 0.3 0.032 13.7 0.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4618 PF15397.6 PVD21572.1 - 0.027 13.9 0.9 0.23 10.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) PA14 PF07691.12 PVD21572.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 PA14 domain Surfac_D-trimer PF09006.11 PVD21572.1 - 0.047 13.6 0.3 4 7.4 0.0 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation WXG100 PF06013.12 PVD21572.1 - 0.055 13.7 3.0 6.7 7.0 0.1 2.2 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Cep57_CLD_2 PF14197.6 PVD21572.1 - 0.07 13.2 1.2 0.49 10.5 0.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 PVD21572.1 - 0.076 13.0 1.0 0.14 12.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 PVD21572.1 - 0.084 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tropomyosin PF00261.20 PVD21572.1 - 0.09 12.1 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin Spc7 PF08317.11 PVD21572.1 - 0.16 10.8 0.8 0.22 10.4 0.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4988 PF16378.5 PVD21572.1 - 0.18 11.5 3.0 15 5.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function DASH_Dad2 PF08654.10 PVD21572.1 - 0.25 11.8 2.4 0.57 10.6 0.2 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 NPV_P10 PF05531.12 PVD21572.1 - 0.31 11.5 2.3 2.3 8.8 2.3 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 PVD21572.1 - 0.62 10.5 3.4 63 4.1 3.4 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Aldo_ket_red PF00248.21 PVD21573.1 - 2.4e-132 440.6 0.0 2.8e-66 223.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Frankia_peptide PF14407.6 PVD21573.1 - 0.022 14.7 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF4060 PF13269.6 PVD21573.1 - 0.028 14.5 0.1 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) HTH_17 PF12728.7 PVD21573.1 - 0.16 12.2 0.0 48 4.2 0.0 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain GP46 PF07409.12 PVD21573.1 - 0.28 10.9 4.1 6.2 6.6 0.2 2.8 3 0 0 3 3 3 0 Phage protein GP46 Aldo_ket_red PF00248.21 PVD21574.1 - 3.6e-69 233.2 0.0 4.1e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3455 PF11937.8 PVD21574.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Aldo_ket_red PF00248.21 PVD21575.1 - 9.3e-69 231.8 0.0 1.1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bindin PF02084.15 PVD21575.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Bindin Aldo_ket_red PF00248.21 PVD21576.1 - 8.1e-69 232.0 0.0 9.2e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD21577.1 - 3.8e-65 220.0 0.0 4.4e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD21578.1 - 1.1e-138 461.3 0.0 3.1e-69 233.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family GP46 PF07409.12 PVD21578.1 - 0.0086 15.8 5.1 0.76 9.6 0.8 2.8 2 0 0 2 2 2 2 Phage protein GP46 Frankia_peptide PF14407.6 PVD21578.1 - 0.039 13.9 0.1 6 6.9 0.0 2.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF1748 PF08520.10 PVD21578.1 - 0.051 13.5 0.1 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) HTH_18 PF12833.7 PVD21578.1 - 0.18 12.1 0.7 78 3.6 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 PVD21579.1 - 9.4e-69 231.8 0.0 1.1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_92 PF01697.27 PVD21580.1 - 6.3e-20 71.9 0.0 9.1e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 KCH PF16944.5 PVD21580.1 - 0.075 12.8 1.7 0.12 12.2 1.7 1.2 1 0 0 1 1 1 0 Fungal potassium channel DND1_DSRM PF14709.7 PVD21580.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Glyco_tranf_2_4 PF13704.6 PVD21580.1 - 0.17 12.5 0.0 0.44 11.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 C1q PF00386.21 PVD21581.1 - 3e-09 37.1 0.1 4.7e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 C1q domain Glyco_transf_92 PF01697.27 PVD21582.1 - 1.6e-19 70.6 0.0 2.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD21582.1 - 0.058 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 DND1_DSRM PF14709.7 PVD21582.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Aldo_ket_red PF00248.21 PVD21583.1 - 1.1e-76 257.9 0.0 1.2e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bindin PF02084.15 PVD21583.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Bindin Aldo_ket_red PF00248.21 PVD21584.1 - 6.6e-78 261.9 0.0 7.5e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bindin PF02084.15 PVD21584.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Bindin Aldo_ket_red PF00248.21 PVD21585.1 - 5e-78 262.3 0.0 5.7e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD21586.1 - 1.4e-78 264.1 0.0 1.6e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD21587.1 - 1.2e-71 241.4 0.0 1.4e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 PVD21588.1 - 8.6e-56 189.2 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21588.1 - 8.5e-42 143.2 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD21588.1 - 2.4e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 PVD21588.1 - 0.0044 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PVD21588.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD21588.1 - 0.041 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aldo_ket_red PF00248.21 PVD21589.1 - 1.3e-75 254.3 0.0 1.5e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_4 PF13637.6 PVD21590.1 - 0 990.2 108.3 1.6e-12 47.7 0.2 41.6 9 8 32 44 44 44 43 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD21590.1 - 1.5e-299 967.7 105.9 3.3e-19 69.2 2.7 26.2 4 4 18 24 24 24 24 Ankyrin repeats (3 copies) Ank PF00023.30 PVD21590.1 - 5.4e-293 934.2 185.5 3.7e-09 36.6 0.5 49.6 49 0 0 49 49 49 48 Ankyrin repeat Ank_3 PF13606.6 PVD21590.1 - 6.8e-268 831.0 112.1 3.2e-06 27.1 0.0 50.7 50 1 0 50 50 50 46 Ankyrin repeat Ank_5 PF13857.6 PVD21590.1 - 3.8e-223 718.6 124.6 7.4e-12 45.3 0.7 34.4 13 8 19 37 37 37 36 Ankyrin repeats (many copies) Bactofilin PF04519.13 PVD21590.1 - 2.5e-05 24.5 3.2 31 5.0 0.1 7.2 7 0 0 7 7 7 0 Polymer-forming cytoskeletal DUF5628 PF18621.1 PVD21590.1 - 1.6 9.2 3.8 1.4e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 Family of unknown function (DUF5628) Self-incomp_S1 PF05938.11 PVD21590.1 - 2.9 8.5 11.8 14 6.3 0.0 7.3 5 2 2 7 7 7 0 Plant self-incompatibility protein S1 Ank_2 PF12796.7 PVD21591.1 - 5.1e-41 139.2 3.7 1.3e-11 44.9 0.0 5.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21591.1 - 1.3e-34 118.2 2.7 4.7e-08 33.4 0.0 6.6 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD21591.1 - 9.3e-34 114.4 12.5 1e-06 28.9 0.0 8.6 6 1 2 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 PVD21591.1 - 1.3e-32 108.1 9.8 1.9e-05 24.7 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 PVD21591.1 - 5.9e-31 106.1 6.0 2.1e-09 37.4 0.2 6.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD21592.1 - 4.1e-101 331.7 20.1 3.8e-17 62.7 0.1 9.4 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21592.1 - 1.9e-88 289.7 18.5 8e-13 48.6 0.1 13.3 4 2 11 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD21592.1 - 3.1e-82 269.5 28.2 1.6e-12 47.4 0.1 13.6 5 2 11 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD21592.1 - 3.5e-81 257.4 15.5 0.00011 22.3 0.0 17.6 17 0 0 17 17 17 14 Ankyrin repeat Ank PF00023.30 PVD21592.1 - 5.8e-81 263.7 41.8 7.9e-07 29.3 0.2 17.1 17 1 0 17 17 17 14 Ankyrin repeat DUF4988 PF16378.5 PVD21592.1 - 0.019 14.6 0.2 1.5 8.5 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function SpoU_sub_bind PF08032.12 PVD21592.1 - 0.03 14.6 0.0 2.5e+02 2.0 0.0 5.4 7 0 0 7 7 7 0 RNA 2'-O ribose methyltransferase substrate binding Fasciclin PF02469.22 PVD21593.1 - 1.6e-27 96.2 0.1 1.9e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Fasciclin domain Laminin_N PF00055.17 PVD21594.1 - 9.7e-35 120.2 0.0 9.7e-35 120.2 0.0 2.9 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 PVD21594.1 - 4e-13 49.3 34.6 3.5e-07 30.3 7.4 3.2 3 0 0 3 3 3 2 Laminin EGF domain EphA2_TM PF14575.6 PVD21594.1 - 0.053 14.4 0.0 0.16 12.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 PVD21594.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain SURF1 PF02104.15 PVD21595.1 - 2.9e-26 92.8 0.0 3.4e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 SURF1 family WD40 PF00400.32 PVD21596.1 - 1.5e-61 202.9 24.3 1.2e-11 44.9 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21596.1 - 2.8e-16 59.6 1.2 2.5e-05 24.5 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD21596.1 - 1.3e-07 31.3 0.0 0.28 10.5 0.0 4.1 2 2 3 5 5 5 3 WD40-like domain eIF2A PF08662.11 PVD21596.1 - 8.3e-07 29.1 0.1 0.12 12.2 0.0 3.0 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD21596.1 - 4.6e-06 25.6 3.0 0.0081 14.9 0.0 4.4 3 1 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PVD21596.1 - 9.6e-06 24.8 1.5 0.0056 15.7 0.0 3.7 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 PVD21596.1 - 0.00031 20.8 0.5 0.036 14.1 0.1 3.5 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 PVD21596.1 - 0.00095 19.0 2.4 2 8.5 0.2 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 PVD21596.1 - 0.0019 18.0 2.5 0.053 13.3 0.3 2.7 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain Marek_SORF3 PF07153.11 PVD21596.1 - 0.032 13.6 0.2 0.062 12.6 0.1 1.5 1 1 0 1 1 1 0 Marek's disease-like virus SORF3 protein MMS1_N PF10433.9 PVD21596.1 - 0.057 12.0 0.0 0.25 9.9 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term RAB3GAP2_N PF14655.6 PVD21596.1 - 0.058 12.6 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Zona_pellucida PF00100.23 PVD21597.1 - 4.3e-22 79.1 0.2 8.3e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain A2M PF00207.22 PVD21598.1 - 5.1e-24 83.9 0.3 7.5e-23 80.2 0.1 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin family TED_complement PF07678.14 PVD21598.1 - 7.8e-15 54.7 0.2 3.5e-08 32.9 0.0 3.6 2 1 1 3 3 3 3 A-macroglobulin TED domain A2M_recep PF07677.14 PVD21598.1 - 5.4e-14 52.7 0.0 1.6e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 PVD21598.1 - 1.9e-10 41.2 0.0 2.9e-08 34.1 0.0 3.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG4 PF17789.1 PVD21598.1 - 7.8e-08 32.4 0.0 2.6e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG4 MG3 PF17791.1 PVD21598.1 - 4e-07 30.2 0.0 1.3e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD21598.1 - 0.0031 17.9 0.3 9.2 6.8 0.0 4.0 3 1 1 4 4 4 2 MG2 domain NTR PF01759.21 PVD21598.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 UNC-6/NTR/C345C module GST_C_3 PF14497.6 PVD21599.1 - 2.9e-06 27.4 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21599.1 - 1.8e-05 25.0 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PVD21599.1 - 0.047 14.4 0.0 0.083 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 PVD21600.1 - 1.5e-21 76.4 0.1 2.2e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD21600.1 - 3.8e-08 33.4 0.1 7.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21600.1 - 1.3e-07 31.9 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD21600.1 - 0.0064 16.5 0.1 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD21600.1 - 0.007 16.8 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PVD21600.1 - 0.026 15.3 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF4405 PF14358.6 PVD21601.1 - 0.35 11.5 2.5 1.4 9.6 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) DUF4228 PF14009.6 PVD21603.1 - 0.072 13.5 0.0 0.079 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RVT_1 PF00078.27 PVD21605.1 - 3.1e-24 85.7 0.1 5.1e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PVD21605.1 - 6.2e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PNMA PF14893.6 PVD21605.1 - 4.6e-06 26.2 0.1 8.3e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 PNMA zf-CCHC PF00098.23 PVD21605.1 - 0.0013 18.7 5.4 0.0013 18.7 5.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 PVD21605.1 - 0.089 12.8 1.4 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 PVD21605.1 - 0.52 10.2 2.4 1.3 8.9 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle GST_C_3 PF14497.6 PVD21606.1 - 2.3e-22 79.0 0.1 3.5e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD21606.1 - 6.4e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21606.1 - 2.3e-06 27.8 0.0 4.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PVD21606.1 - 0.0053 17.3 0.1 0.027 15.1 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD21606.1 - 0.0065 16.5 0.2 0.068 13.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD21606.1 - 0.018 15.8 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 PVD21607.1 - 1.1e-23 83.2 0.9 1.7e-23 82.7 0.9 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD21607.1 - 6.7e-10 39.1 0.2 1e-09 38.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21607.1 - 3.7e-07 30.4 0.1 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD21607.1 - 0.001 19.0 0.1 0.0081 16.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD21607.1 - 0.022 15.2 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Nif11 PF07862.11 PVD21607.1 - 0.081 13.2 0.4 18 5.7 0.4 2.8 2 1 0 2 2 2 0 Nif11 domain GST_N_4 PF17172.4 PVD21607.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 PVD21608.1 - 3.2e-21 75.4 0.0 4.4e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21608.1 - 1.2e-06 28.8 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD21608.1 - 1.2e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD21608.1 - 0.006 17.3 0.0 0.016 15.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 PVD21608.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD21609.1 - 9.5e-22 77.1 0.1 1.5e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21609.1 - 8.7e-10 38.8 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD21609.1 - 3.4e-08 33.6 0.0 5.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD21609.1 - 0.0073 16.3 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD21609.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PVD21609.1 - 0.082 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 PVD21609.1 - 0.095 13.3 0.0 0.18 12.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD21610.1 - 1.3e-21 76.6 0.0 1.9e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD21610.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD21610.1 - 2.1e-07 31.2 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PVD21610.1 - 0.016 16.0 0.0 0.03 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Methyltransf_11 PF08241.12 PVD21611.1 - 8e-13 48.9 0.5 6.7e-12 45.9 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD21611.1 - 1.4e-09 38.6 0.1 4.6e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD21611.1 - 0.00079 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3148 PF11347.8 PVD21611.1 - 0.1 12.4 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Methyltransf_12 PF08242.12 PVD21611.1 - 0.11 13.2 0.0 0.37 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Laminin_II PF06009.12 PVD21612.1 - 0.01 15.8 16.2 0.13 12.2 0.5 3.9 3 1 1 4 4 4 0 Laminin Domain II DUF745 PF05335.13 PVD21612.1 - 0.074 12.8 19.5 0.73 9.5 11.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 PVD21612.1 - 0.55 10.5 7.3 20 5.5 0.0 4.6 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.5 PVD21612.1 - 0.93 9.8 17.5 0.15 12.4 6.7 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Sec8_exocyst PF04048.14 PVD21612.1 - 1.2 9.0 12.0 0.39 10.6 0.3 3.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Phage_GP20 PF06810.11 PVD21612.1 - 1.4 8.7 26.2 0.54 10.1 6.2 3.8 3 1 1 4 4 4 0 Phage minor structural protein GP20 Syntaxin-6_N PF09177.11 PVD21612.1 - 1.5 9.5 20.8 2.4 8.8 1.1 4.5 2 1 1 4 4 4 0 Syntaxin 6, N-terminal DUF4795 PF16043.5 PVD21612.1 - 2.6 7.6 31.6 2.8 7.5 3.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 PVD21612.1 - 4.9 7.6 31.0 2 8.8 15.0 3.4 2 1 1 3 3 3 0 Fez1 CC2-LZ PF16516.5 PVD21612.1 - 8 6.9 21.1 2.9 8.3 3.7 4.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Swi5 PF07061.11 PVD21613.1 - 1.6e-20 72.9 2.4 2.8e-20 72.2 2.4 1.4 1 0 0 1 1 1 1 Swi5 Phage_GP20 PF06810.11 PVD21613.1 - 0.00082 19.2 0.6 0.0015 18.4 0.6 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 PKcGMP_CC PF16808.5 PVD21613.1 - 0.022 14.6 2.4 0.043 13.7 2.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4140 PF13600.6 PVD21613.1 - 0.026 14.9 0.2 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YflT PF11181.8 PVD21613.1 - 0.03 14.8 0.4 0.056 14.0 0.4 1.5 1 0 0 1 1 1 0 Heat induced stress protein YflT FlxA PF14282.6 PVD21613.1 - 0.039 13.9 1.0 0.07 13.1 1.0 1.5 1 0 0 1 1 1 0 FlxA-like protein Spc24 PF08286.11 PVD21613.1 - 0.12 12.7 0.8 0.21 11.9 0.3 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NCU-G1 PF15065.6 PVD21613.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 AAA-ATPase_like PF09820.9 PVD21615.1 - 0.17 11.3 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 Predicted AAA-ATPase Ank_2 PF12796.7 PVD21616.1 - 3.5e-17 62.8 0.7 1.8e-06 28.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD21616.1 - 3.7e-08 33.0 1.3 0.19 12.4 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 PVD21616.1 - 4.1e-07 30.4 0.7 0.00054 20.5 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD21616.1 - 8e-07 29.2 0.5 0.065 13.7 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat SOCS_box PF07525.16 PVD21616.1 - 1.6e-06 28.4 0.1 3.2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 PVD21616.1 - 0.00034 20.8 1.6 0.013 15.8 0.3 3.5 2 2 3 5 5 5 1 Ankyrin repeats (many copies) MLD PF11647.8 PVD21616.1 - 0.045 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Membrane Localization Domain Phospholamban PF04272.14 PVD21616.1 - 0.045 13.2 0.5 0.22 11.0 0.1 2.3 2 0 0 2 2 2 0 Phospholamban Tox-URI2 PF15653.6 PVD21617.1 - 0.43 10.9 4.0 0.62 10.4 4.0 1.3 1 0 0 1 1 1 0 URI fold toxin 2 AAA_16 PF13191.6 PVD21618.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 PVD21618.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD21618.1 - 0.047 12.8 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 PVD21618.1 - 0.076 13.4 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD21618.1 - 0.096 13.0 0.1 0.28 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 PVD21618.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3560 PF12083.8 PVD21618.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) AAA_11 PF13086.6 PVD21618.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 PVD21618.1 - 0.15 11.6 0.1 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 PVD21618.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2958 PF11171.8 PVD21619.1 - 0.064 13.5 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) EF-hand_1 PF00036.32 PVD21620.1 - 3.7e-08 32.4 0.3 7.7e-08 31.4 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PVD21620.1 - 3.4e-07 30.6 0.1 4.3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD21620.1 - 1.9e-05 24.2 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 PVD21620.1 - 5e-05 22.6 0.1 8.2e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 PVD21620.1 - 0.042 13.7 0.4 0.095 12.6 0.2 1.7 1 1 1 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD21620.1 - 0.043 14.1 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD21620.1 - 0.082 12.9 0.1 0.097 12.6 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF5552 PF17706.1 PVD21620.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5552) DUF4632 PF15451.6 PVD21622.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4632) Dicty_REP PF05086.12 PVD21623.1 - 7.5 4.4 7.6 10 4.0 7.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DSHCT PF08148.12 PVD21624.1 - 3.1e-51 173.3 0.4 6.7e-51 172.2 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 PVD21624.1 - 7.6e-37 127.7 0.5 1.3e-36 127.0 0.5 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain Ski2_N PF17911.1 PVD21624.1 - 3.4e-32 111.1 0.0 9.9e-32 109.6 0.0 1.8 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 PVD21624.1 - 2.4e-17 63.3 0.2 6.8e-17 61.8 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PVD21624.1 - 5.3e-06 26.5 0.1 1.3e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PVD21624.1 - 1e-05 25.8 0.0 4.2e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 PVD21624.1 - 0.013 14.6 0.5 0.031 13.4 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Rhomboid PF01694.22 PVD21625.1 - 5.7e-23 81.6 8.8 5.7e-23 81.6 8.8 2.2 3 1 0 3 3 3 1 Rhomboid family EF-hand_7 PF13499.6 PVD21625.1 - 0.12 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair Pox_EPC_I2-L1 PF12575.8 PVD21625.1 - 3.3 8.0 7.3 19 5.6 0.0 3.6 4 0 0 4 4 4 0 Poxvirus entry protein complex L1 and I2 Polysacc_synt_C PF14667.6 PVD21625.1 - 8 6.5 13.6 0.15 12.1 6.0 2.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain IER PF05760.12 PVD21626.1 - 5.2e-26 92.7 11.6 3.8e-25 89.9 11.6 1.9 1 1 0 1 1 1 1 Immediate early response protein (IER) HA2 PF04408.23 PVD21627.1 - 1.3e-21 76.9 0.0 1.3e-21 76.9 0.0 3.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD21627.1 - 3.1e-20 72.3 0.2 8e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD21627.1 - 8.4e-11 42.2 0.0 2.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD21627.1 - 8.1e-08 32.2 0.0 4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 PVD21627.1 - 1.9e-05 24.5 0.0 8.8e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD21627.1 - 5.6e-05 23.5 0.6 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD21627.1 - 0.00032 21.0 0.0 0.0015 18.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD21627.1 - 0.00078 18.6 0.0 0.0021 17.2 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 PVD21627.1 - 0.03 14.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain ROQ_II PF18386.1 PVD21628.1 - 2.4e-32 110.5 1.1 4.6e-32 109.6 1.1 1.5 1 0 0 1 1 1 1 Roquin II domain zf-CCCH PF00642.24 PVD21628.1 - 1.8e-07 30.9 1.5 4e-07 29.8 1.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD21628.1 - 7e-05 22.7 0.9 0.00017 21.5 0.9 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PVD21628.1 - 0.00084 19.1 0.5 0.0016 18.2 0.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger P3A PF08727.11 PVD21628.1 - 0.013 14.8 0.1 0.037 13.4 0.1 1.7 1 0 0 1 1 1 0 Poliovirus 3A protein like Torus PF16131.5 PVD21628.1 - 0.036 14.8 1.1 0.067 13.9 0.2 1.9 2 0 0 2 2 2 0 Torus domain DUF743 PF05332.11 PVD21628.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) zf-CCCH_2 PF14608.6 PVD21628.1 - 1.3 9.6 4.4 0.52 10.9 1.1 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAP2 PF01569.21 PVD21629.1 - 9.5e-18 64.3 5.1 4.8e-17 62.0 5.1 2.1 1 1 0 1 1 1 1 PAP2 superfamily CbiM PF01891.16 PVD21629.1 - 0.00086 19.2 2.1 0.0015 18.4 2.1 1.3 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region DUF212 PF02681.14 PVD21629.1 - 0.0026 17.9 1.2 0.15 12.2 0.0 2.3 1 1 1 2 2 2 1 Divergent PAP2 family Glycos_transf_4 PF00953.21 PVD21629.1 - 0.023 14.7 5.2 0.035 14.1 5.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 UbiA PF01040.18 PVD21629.1 - 0.2 10.9 12.0 0.04 13.2 7.5 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family Carn_acyltransf PF00755.20 PVD21630.1 - 6.2e-196 652.5 0.0 7.1e-196 652.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase NCD1 PF04904.13 PVD21630.1 - 0.07 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) RNA_pol_Rpb1_4 PF05000.17 PVD21630.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 ANF_receptor PF01094.28 PVD21631.1 - 2e-66 224.5 0.7 3.1e-66 223.9 0.2 1.4 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD21631.1 - 6.2e-56 189.8 7.7 1e-55 189.1 7.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 PVD21631.1 - 7.2e-12 45.6 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PhoLip_ATPase_C PF16212.5 PVD21631.1 - 0.036 13.8 6.1 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal LIM PF00412.22 PVD21632.1 - 6e-07 29.6 5.2 1.1e-06 28.8 5.2 1.4 1 0 0 1 1 1 1 LIM domain E3_UbLigase_R4 PF13764.6 PVD21633.1 - 0 1037.6 1.1 0 1037.6 1.1 2.4 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 PVD21633.1 - 7.7e-07 29.2 15.5 7.7e-07 29.2 15.5 3.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) EF-hand_5 PF13202.6 PVD21634.1 - 1.8e-11 43.0 2.0 0.00014 21.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 PVD21634.1 - 9.6e-10 37.3 5.1 0.00041 19.7 0.1 3.9 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD21634.1 - 1.3e-08 34.1 3.4 0.0023 17.7 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD21634.1 - 3.7e-07 30.5 7.4 0.017 15.6 0.1 4.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD21634.1 - 8e-06 25.6 2.0 0.012 15.4 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 PVD21634.1 - 0.015 15.5 1.4 3.2 8.0 0.2 2.5 1 1 1 2 2 2 0 Dockerin type I domain DUF2644 PF10841.8 PVD21634.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Nup188 PF10487.9 PVD21635.1 - 6e-138 461.3 2.6 2.1e-131 439.7 2.6 2.6 1 1 1 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Sulfotransfer_2 PF03567.14 PVD21636.1 - 3.1e-26 92.8 0.1 3.1e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD21636.1 - 5e-05 22.9 0.1 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain LRAT PF04970.13 PVD21637.1 - 2.4e-24 86.0 0.0 9.8e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD21637.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.7 2 0 0 2 2 2 1 NlpC/P60 family Sel1 PF08238.12 PVD21638.1 - 5.2e-10 39.7 8.0 4e-09 36.8 0.2 3.1 3 0 0 3 3 3 2 Sel1 repeat DS PF01916.17 PVD21640.1 - 6.9e-131 435.7 0.0 8.7e-131 435.4 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase FLYWCH PF04500.16 PVD21640.1 - 1.1e-10 41.5 4.2 2.6e-10 40.3 4.2 1.7 1 0 0 1 1 1 1 FLYWCH zinc finger domain CDC73_N PF16050.5 PVD21641.1 - 6.9e-128 426.1 0.4 1e-127 425.5 0.4 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 PVD21641.1 - 9.4e-52 174.9 0.0 1.9e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Glucosamine_iso PF01182.20 PVD21642.1 - 1.6e-66 224.4 0.0 1.8e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2b PF00587.25 PVD21644.1 - 8.8e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PVD21644.1 - 0.00015 21.9 2.5 0.00027 21.1 2.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RGS PF00615.19 PVD21645.1 - 5.3e-38 129.9 0.1 8.8e-38 129.2 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Macoilin PF09726.9 PVD21646.1 - 0.085 11.4 11.0 0.1 11.1 11.0 1.2 1 0 0 1 1 1 0 Macoilin family CASP_C PF08172.12 PVD21646.1 - 1 8.7 4.4 0.96 8.7 1.4 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4348 PF14254.6 PVD21647.1 - 0.12 11.7 0.6 0.15 11.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) RT_RNaseH_2 PF17919.1 PVD21650.1 - 2e-39 133.6 0.0 3.7e-23 81.4 0.0 3.7 1 1 2 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD21650.1 - 4e-34 117.1 0.0 3.4e-28 98.0 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase rve PF00665.26 PVD21650.1 - 8.9e-15 54.9 0.0 2.4e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 PVD21650.1 - 1.4e-11 44.3 0.5 3.6e-11 43.0 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain HEAT_2 PF13646.6 PVD21651.1 - 1.7e-06 28.3 0.5 0.017 15.5 0.1 4.2 1 1 3 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PVD21651.1 - 0.0038 17.7 4.2 1.7 9.2 0.1 4.5 3 2 1 4 4 4 2 HEAT-like repeat Proteasom_PSMB PF10508.9 PVD21651.1 - 0.0052 15.4 4.6 0.26 9.7 0.2 3.1 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit SEO_C PF14577.6 PVD21651.1 - 0.037 13.5 0.4 2.9 7.3 0.0 2.9 2 1 1 3 3 3 0 Sieve element occlusion C-terminus DUF4521 PF15021.6 PVD21651.1 - 0.093 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Arm PF00514.23 PVD21651.1 - 0.76 9.9 5.4 43 4.3 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 PVD21652.1 - 1.9e-37 129.0 0.0 1.8e-33 115.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 PVD21652.1 - 6.3e-37 126.0 8.3 1.6e-14 54.3 0.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21652.1 - 1.6e-35 121.0 4.3 1.9e-13 50.6 0.4 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Pkinase PF00069.25 PVD21652.1 - 1.8e-31 109.5 0.0 3.3e-31 108.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 PVD21652.1 - 1.6e-28 95.6 5.0 0.0016 18.8 0.3 8.8 7 1 1 8 8 8 5 Ankyrin repeat Ank PF00023.30 PVD21652.1 - 3.1e-25 87.4 19.0 4.6e-05 23.7 0.0 8.2 8 1 0 8 8 7 5 Ankyrin repeat Ank_5 PF13857.6 PVD21652.1 - 2.1e-22 78.9 7.8 2.5e-05 24.5 0.1 7.8 3 1 5 8 8 8 5 Ankyrin repeats (many copies) APH PF01636.23 PVD21652.1 - 0.00012 22.0 0.1 0.0026 17.7 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD21652.1 - 0.003 16.9 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1843 PF08898.10 PVD21652.1 - 0.048 14.2 0.0 15 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Kinase-like PF14531.6 PVD21652.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 PVD21652.1 - 0.1 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 PVD21652.1 - 0.11 12.1 0.6 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 RIO1 family VTC PF09359.10 PVD21652.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 VTC domain LAP1C PF05609.12 PVD21653.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) I-set PF07679.16 PVD21655.1 - 1.2e-17 63.8 0.1 4.1e-09 36.4 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21655.1 - 1.1e-14 54.8 1.9 1.9e-08 34.8 0.1 3.6 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD21655.1 - 1.3e-11 44.5 0.3 1.4e-05 25.2 0.0 3.6 2 1 1 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD21655.1 - 8.3e-10 38.9 2.5 0.00054 20.3 0.0 4.3 3 1 1 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD21655.1 - 5.1e-09 36.3 2.0 0.072 13.3 0.0 4.4 3 1 0 3 3 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD21655.1 - 0.0049 16.9 0.0 2.8 8.1 0.0 2.9 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD21655.1 - 0.0083 15.7 0.0 1.9 8.1 0.0 3.2 2 1 1 3 3 3 1 Immunoglobulin domain Triabin PF03973.13 PVD21657.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Triabin Lipocalin_2 PF08212.12 PVD21657.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Lipocalin-like domain I-set PF07679.16 PVD21658.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21658.1 - 0.084 13.5 0.0 0.23 12.1 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 PVD21659.1 - 5.1e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD21659.1 - 0.00019 21.9 0.0 0.00034 21.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD21659.1 - 0.00037 20.5 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD21659.1 - 0.0034 17.5 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD21659.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain MG1 PF17790.1 PVD21661.1 - 3e-10 40.4 0.0 4.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Macroglobulin domain MG1 TED_complement PF07678.14 PVD21662.1 - 2.9e-99 332.1 0.0 8.5e-98 327.2 0.0 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain A2M_recep PF07677.14 PVD21662.1 - 2e-29 102.1 0.3 5.8e-29 100.6 0.3 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M PF00207.22 PVD21662.1 - 4.6e-24 84.1 0.0 1.2e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 PVD21662.1 - 1.3e-19 70.9 0.0 1.5e-18 67.5 0.0 2.7 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG4 PF17789.1 PVD21662.1 - 4.4e-07 30.0 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Macroglobulin domain MG4 MG3 PF17791.1 PVD21662.1 - 1.1e-06 28.8 0.0 3.7e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 NTR PF01759.21 PVD21662.1 - 1.5e-06 28.0 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Prenyltrans PF00432.21 PVD21662.1 - 9.7e-05 22.0 0.0 0.36 10.6 0.0 3.5 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 PVD21662.1 - 0.001 18.3 0.1 0.01 15.0 0.0 2.1 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Transglut_C PF00927.22 PVD21662.1 - 0.029 14.5 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Arteri_GP4 PF02497.15 PVD21662.1 - 0.12 12.5 0.4 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Arterivirus glycoprotein DUF5420 PF17457.2 PVD21663.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5420) PSP94 PF05825.11 PVD21665.1 - 0.006 17.1 1.0 0.009 16.6 1.0 1.3 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) PSP94 PF05825.11 PVD21666.1 - 0.0024 18.4 0.9 0.0025 18.3 0.9 1.2 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) EAV_GP5 PF15981.5 PVD21666.1 - 0.062 13.7 1.1 0.087 13.2 1.1 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus Neur_chan_LBD PF02931.23 PVD21667.1 - 2e-25 89.6 5.0 6.5e-22 78.0 1.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21667.1 - 6.3e-23 82.1 2.2 6.3e-23 82.1 2.2 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4870 PF09685.10 PVD21667.1 - 6.9 6.8 12.3 3.6 7.8 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Neur_chan_LBD PF02931.23 PVD21668.1 - 3.5e-45 154.1 0.7 5.2e-45 153.5 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21668.1 - 9.9e-15 55.2 25.3 8.6e-11 42.4 9.0 3.1 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 PVD21668.1 - 0.23 10.8 1.4 0.4 10.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Herpes_US9 PF06072.11 PVD21668.1 - 4.8 7.1 9.6 9 6.3 0.0 3.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Neur_chan_LBD PF02931.23 PVD21669.1 - 1.3e-34 119.6 1.7 1.9e-34 119.0 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21669.1 - 6.9e-22 78.7 2.2 1.4e-21 77.7 1.5 1.8 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD21670.1 - 7.2e-36 123.7 2.2 3.9e-34 118.0 2.2 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21670.1 - 2e-10 41.2 1.2 2e-10 41.2 1.2 2.3 2 1 1 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 PVD21670.1 - 0.082 12.3 2.1 7.3 5.9 0.6 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Trehalose_recp PF06151.13 PVD21670.1 - 0.089 11.4 2.2 0.33 9.5 0.0 2.0 2 0 0 2 2 2 0 Trehalose receptor MNSV_P7B PF06692.11 PVD21670.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Neur_chan_LBD PF02931.23 PVD21671.1 - 5.5e-42 143.6 2.8 7.8e-42 143.1 2.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4064 PF13273.6 PVD21671.1 - 0.021 15.1 0.7 3.5 8.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Pro_sub2 PF18513.1 PVD21671.1 - 0.099 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Prodomain subtilisin 2 4HB_MCP_1 PF12729.7 PVD21671.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Neur_chan_LBD PF02931.23 PVD21672.1 - 1.1e-46 159.0 3.2 1.6e-46 158.5 3.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD21672.1 - 1.1e-21 78.1 4.3 1.1e-21 78.1 4.3 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF805 PF05656.14 PVD21672.1 - 1.9 8.9 4.5 76 3.8 3.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF805) 4HB_MCP_1 PF12729.7 PVD21672.1 - 8.2 5.9 6.3 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CBM_14 PF01607.24 PVD21674.1 - 1.9e-05 24.8 6.1 1.9e-05 24.8 6.1 2.7 2 1 1 3 3 3 1 Chitin binding Peritrophin-A domain Mito_fiss_reg PF05308.11 PVD21674.1 - 4.1 7.4 4.9 5.6 7.0 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Sporozoite_P67 PF05642.11 PVD21674.1 - 5.3 5.0 6.8 5.1 5.1 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Y_phosphatase PF00102.27 PVD21675.1 - 1.1e-11 44.7 0.2 2.1e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD21675.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD21676.1 - 6.9e-47 160.0 0.0 1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD21676.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTP_tm PF18861.1 PVD21676.1 - 0.17 11.9 0.4 22 5.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MAP65_ASE1 PF03999.12 PVD21676.1 - 0.4 9.3 1.5 0.62 8.7 1.5 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) fn3 PF00041.21 PVD21677.1 - 3.2e-14 53.0 1.9 5.9e-10 39.4 0.0 3.3 3 1 0 3 3 3 2 Fibronectin type III domain Interfer-bind PF09294.10 PVD21677.1 - 0.014 15.7 0.0 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 PVD21677.1 - 0.11 13.0 6.3 0.18 12.4 0.1 3.4 3 2 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain VWA PF00092.28 PVD21678.1 - 1.4e-37 129.6 0.2 2.2e-37 129.0 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD21678.1 - 5.3e-13 49.5 1.3 1.1e-12 48.6 1.3 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD21678.1 - 0.0097 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C2H2 PF00096.26 PVD21679.1 - 3.8e-20 71.1 31.3 1.4e-05 25.2 2.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD21679.1 - 2e-16 59.6 33.7 2.7e-07 30.7 2.1 4.8 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD21679.1 - 5.9e-16 57.8 26.7 0.0021 18.8 3.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD21679.1 - 1.5e-05 24.8 22.6 0.0035 17.3 2.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD21679.1 - 7.6e-05 22.4 20.3 0.0011 18.7 3.8 4.0 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-Di19 PF05605.12 PVD21679.1 - 0.00015 22.0 4.4 0.00015 22.0 4.4 3.0 2 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 PVD21679.1 - 0.0089 16.1 11.4 0.15 12.2 2.7 3.2 1 1 1 3 3 3 2 Zinc ribbon domain zinc_ribbon_15 PF17032.5 PVD21679.1 - 0.0089 16.8 6.7 0.93 10.3 0.9 2.4 2 0 0 2 2 2 2 zinc-ribbon family zf-C2H2_jaz PF12171.8 PVD21679.1 - 0.0089 16.3 11.0 2.7 8.4 0.3 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 PVD21679.1 - 0.014 15.0 13.3 3.6 7.3 0.7 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 PVD21679.1 - 0.045 13.8 19.0 0.13 12.4 2.8 3.7 2 1 2 4 4 4 0 BED zinc finger Prok-RING_1 PF14446.6 PVD21679.1 - 0.046 13.7 8.6 5.1 7.1 0.1 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-CHCC PF10276.9 PVD21679.1 - 0.089 12.9 8.4 0.22 11.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger domain Cys_rich_CPXG PF14255.6 PVD21679.1 - 0.12 12.3 1.1 1.1 9.2 0.7 2.6 2 1 0 2 2 2 0 Cysteine-rich CPXCG HalOD2 PF18547.1 PVD21679.1 - 0.12 12.2 6.4 2.1 8.3 0.3 3.5 2 1 1 3 3 3 0 Halobacterial output domain 2 GAGA PF09237.11 PVD21679.1 - 0.14 12.0 6.5 2 8.3 0.0 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2HE PF16278.5 PVD21679.1 - 0.27 11.7 0.1 0.27 11.7 0.1 4.3 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 PVD21679.1 - 0.33 11.3 16.3 21 5.5 8.9 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 PVD21679.1 - 0.44 10.6 8.7 1.3 9.1 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fer4_9 PF13187.6 PVD21679.1 - 1.1 9.5 5.4 2.7 8.2 0.0 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-C2H2_3rep PF18868.1 PVD21679.1 - 1.3 9.7 10.4 71 4.1 10.4 3.3 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats MCM_OB PF17207.3 PVD21679.1 - 4.1 7.3 8.0 1.3 8.9 2.0 2.2 1 1 1 2 2 2 0 MCM OB domain zf-AN1 PF01428.16 PVD21679.1 - 5.8 7.2 16.6 5.6 7.2 0.2 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger FYDLN_acid PF09538.10 PVD21679.1 - 6.4 7.5 6.0 65 4.3 3.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) PknG_rubred PF16919.5 PVD21679.1 - 7.7 6.7 9.8 0.81 9.8 1.4 2.7 1 1 2 3 3 3 0 Protein kinase G rubredoxin domain Zn-C2H2_12 PF18112.1 PVD21679.1 - 8.1 7.0 9.2 14 6.2 0.4 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain DUF3268 PF11672.8 PVD21679.1 - 9.2 6.6 8.5 4.3 7.7 0.6 2.6 1 1 1 2 2 2 0 zinc-finger-containing domain PTPA PF03095.15 PVD21680.1 - 1.4e-123 412.2 0.0 1.6e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WW PF00397.26 PVD21681.1 - 8.6e-05 22.5 0.3 8.6e-05 22.5 0.3 1.9 2 0 0 2 2 2 1 WW domain CUE PF02845.16 PVD21681.1 - 0.0002 21.0 0.4 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 CUE domain dsrm PF00035.26 PVD21682.1 - 7.9e-16 58.5 0.2 1.9e-12 47.7 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif HA2 PF04408.23 PVD21682.1 - 2.3e-15 56.8 0.0 5.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PVD21682.1 - 2.4e-15 56.9 0.0 6.3e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PVD21682.1 - 2.4e-15 56.7 0.1 5.9e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ATPase PF06745.13 PVD21682.1 - 0.0033 16.8 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 KaiC DEAD PF00270.29 PVD21682.1 - 0.015 15.1 0.1 0.11 12.3 0.0 2.3 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_11 PF13086.6 PVD21682.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MAP70 PF07058.11 PVD21682.1 - 0.25 10.0 0.1 0.42 9.3 0.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 CUB PF00431.20 PVD21683.1 - 1.1e-25 90.2 0.0 3.5e-20 72.4 0.0 2.7 2 0 0 2 2 2 2 CUB domain Reprolysin PF01421.19 PVD21683.1 - 3e-17 63.2 0.0 9.4e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 PVD21683.1 - 2.2e-16 60.3 0.2 5.6e-15 55.8 0.2 2.3 1 1 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 PVD21683.1 - 2.6e-16 59.9 4.9 2.6e-16 59.9 4.9 6.9 6 3 1 7 7 3 1 ADAM cysteine-rich domain TSP_1 PF00090.19 PVD21683.1 - 2.6e-15 56.4 35.7 8.7e-11 41.9 6.8 7.4 7 0 0 7 7 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 PVD21683.1 - 2.8e-14 53.7 0.4 7.2e-14 52.4 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD21683.1 - 1.8e-10 41.4 0.1 3.9e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD21683.1 - 1.5e-06 28.0 0.2 3.2e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 PVD21683.1 - 3.6e-06 27.0 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ShK PF01549.24 PVD21683.1 - 4.6e-05 23.9 22.1 6.5e-05 23.4 5.3 8.9 10 0 0 10 10 7 3 ShK domain-like Reprolysin_2 PF13574.6 PVD21683.1 - 0.002 18.1 0.1 0.0054 16.7 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 PVD21683.1 - 0.028 14.5 0.2 0.093 12.8 0.2 1.9 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 PVD21683.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Matrixin Lin-8 PF03353.15 PVD21684.1 - 0.37 10.3 8.5 0.012 15.2 1.8 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1635 PF07795.11 PVD21684.1 - 0.96 9.3 13.9 0.13 12.1 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Dimer_Tnp_hAT PF05699.14 PVD21685.1 - 6.9e-05 22.6 0.3 0.0002 21.1 0.3 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo_endo_phos_2 PF14529.6 PVD21686.1 - 0.00026 20.8 0.2 0.0003 20.6 0.2 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TilS_C PF11734.8 PVD21687.1 - 0.087 12.3 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 TilS substrate C-terminal domain LIM PF00412.22 PVD21689.1 - 3.3e-29 100.9 21.3 1.3e-14 54.1 4.0 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 PVD21689.1 - 0.061 13.2 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Homeodomain C1q PF00386.21 PVD21690.1 - 5e-11 42.9 0.4 7e-11 42.4 0.4 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD21690.1 - 0.032 14.1 0.5 0.046 13.6 0.5 1.1 1 0 0 1 1 1 0 BclA C-terminal domain DUF4692 PF15763.5 PVD21692.1 - 0.13 12.8 3.1 0.33 11.4 3.1 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Kelch_1 PF01344.25 PVD21693.1 - 3e-75 247.6 8.2 3.1e-13 49.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD21693.1 - 5.3e-43 144.0 7.7 3.3e-09 36.7 0.1 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PVD21693.1 - 2.8e-30 104.1 11.0 1.1e-05 25.3 0.0 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD21693.1 - 8.2e-30 102.5 9.1 2.7e-06 27.5 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD21693.1 - 1.4e-29 100.9 7.4 6.3e-05 22.8 0.0 6.6 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 PVD21693.1 - 4.5e-24 84.8 0.1 9.3e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 PVD21693.1 - 7.2e-13 48.2 3.5 0.2 11.7 0.0 5.7 5 0 0 5 5 5 4 Kelch motif BACK PF07707.15 PVD21693.1 - 6.4e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF1668 PF07893.13 PVD21693.1 - 0.0013 18.2 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) BTB_2 PF02214.22 PVD21693.1 - 0.094 13.1 0.1 2.4 8.6 0.0 2.6 3 0 0 3 3 2 0 BTB/POZ domain Glyoxal_oxid_N PF07250.11 PVD21693.1 - 0.22 10.7 3.1 6.4 5.9 0.0 2.8 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus TruB_N PF01509.18 PVD21694.1 - 8.8e-13 48.9 0.0 1.4e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PVD21694.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Methyltransf_23 PF13489.6 PVD21695.1 - 0.013 15.4 0.0 0.93 9.3 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Prd1-P2 PF09214.11 PVD21695.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Methyltransf_23 PF13489.6 PVD21696.1 - 0.034 14.0 0.0 2.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain CCDC-167 PF15188.6 PVD21696.1 - 2.5 8.5 5.9 8 6.9 0.8 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 T-box PF00907.22 PVD21697.1 - 9.2e-59 198.8 0.0 1.3e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 T-box Methyltransf_23 PF13489.6 PVD21698.1 - 0.038 13.8 0.0 4.6 7.0 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PVD21699.1 - 0.046 13.5 0.0 1.7 8.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF348 PF03990.14 PVD21699.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Prd1-P2 PF09214.11 PVD21699.1 - 0.15 10.8 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Methyltransf_23 PF13489.6 PVD21700.1 - 0.0043 16.9 0.0 0.51 10.2 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Glyco_transf_92 PF01697.27 PVD21702.1 - 1.6e-30 106.6 0.0 2.4e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD21702.1 - 8.1e-05 23.1 0.1 0.00026 21.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 TMEM95 PF15203.6 PVD21702.1 - 0.11 12.1 0.9 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 TMEM95 family GPI2 PF06432.11 PVD21703.1 - 1.9e-14 53.8 1.4 2.1e-14 53.7 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PMSR PF01625.21 PVD21704.1 - 0.1 12.8 6.4 0.27 11.4 6.4 1.7 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase OGG_N PF07934.12 PVD21705.1 - 1e-19 70.8 0.2 2e-18 66.6 0.2 2.3 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 PVD21705.1 - 2.4e-11 44.0 0.0 4.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PVD21705.1 - 0.00042 20.0 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif LRR_9 PF14580.6 PVD21706.1 - 1.3e-08 34.6 0.4 6.4e-08 32.3 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 PVD21706.1 - 7.5e-07 29.4 6.8 4e-06 27.1 0.4 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD21706.1 - 9.8e-06 25.3 1.3 3.2e-05 23.6 0.4 2.5 2 0 0 2 2 2 1 Leucine rich repeat IQ PF00612.27 PVD21706.1 - 0.0012 18.5 0.8 0.0012 18.5 0.8 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif HNF-1_N PF04814.13 PVD21706.1 - 0.0071 17.0 11.5 0.21 12.2 0.3 2.5 2 1 0 2 2 2 2 Hepatocyte nuclear factor 1 (HNF-1), N terminus Acetyltransf_CG PF14542.6 PVD21706.1 - 0.062 13.4 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Ribosomal_S2 PF00318.20 PVD21707.1 - 7.9e-43 146.2 0.2 4.7e-23 81.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Aminotran_1_2 PF00155.21 PVD21708.1 - 3.2e-14 52.9 0.0 3.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PVD21708.1 - 0.00033 19.6 0.0 0.00079 18.3 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase RNA_Me_trans PF04252.13 PVD21708.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Bromodomain PF00439.25 PVD21709.1 - 3.7e-44 148.7 3.0 4.2e-23 81.2 0.3 2.8 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 PVD21709.1 - 2.5e-28 98.0 0.2 2.5e-28 98.0 0.2 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 PVD21709.1 - 4.2e-16 58.2 8.3 4.2e-16 58.2 8.3 4.0 3 1 1 4 4 4 1 C-terminal domain of bromodomain protein 4 YL1 PF05764.13 PVD21709.1 - 1.5e-05 25.3 12.0 1.5e-05 25.3 12.0 4.7 4 1 0 4 4 4 1 YL1 nuclear protein WD40 PF00400.32 PVD21710.1 - 1.3e-62 206.2 18.3 5.1e-10 39.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21710.1 - 1.2e-25 89.6 1.1 0.00082 19.6 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD21710.1 - 5.3e-15 55.8 0.7 3.2e-07 30.4 0.0 3.6 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD21710.1 - 2.3e-14 53.0 4.0 0.0053 15.5 0.1 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 PVD21710.1 - 9.4e-07 28.4 0.1 0.016 14.5 0.0 3.2 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 PVD21710.1 - 5.4e-06 25.6 1.6 2.3 7.1 0.0 4.2 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 PVD21710.1 - 3e-05 23.1 4.8 1.2 8.0 0.0 4.3 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 PVD21710.1 - 0.00013 20.5 0.1 0.017 13.4 0.0 2.8 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 PVD21710.1 - 0.016 14.3 0.0 0.26 10.3 0.0 2.5 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 PVD21710.1 - 0.023 13.2 0.0 0.35 9.4 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.11 PVD21710.1 - 0.03 14.0 1.9 27 4.4 0.1 4.1 3 1 1 4 4 4 0 TUP1-like enhancer of split Kelch_6 PF13964.6 PVD21710.1 - 0.1 12.9 0.8 2.6 8.5 0.1 3.0 2 1 0 2 2 2 0 Kelch motif MFS_1 PF07690.16 PVD21711.1 - 7.9e-05 21.7 20.8 0.003 16.5 7.8 3.3 3 0 0 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 PVD21711.1 - 0.00014 21.6 1.7 0.00014 21.6 1.7 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SecE PF00584.20 PVD21711.1 - 1 9.3 0.0 1 9.3 0.0 2.9 4 0 0 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex SAGA-Tad1 PF12767.7 PVD21712.1 - 6.4e-19 68.6 1.9 7.6e-12 45.5 0.6 2.3 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SURF4 PF02077.15 PVD21713.1 - 1.3e-121 405.3 3.5 1.5e-121 405.1 3.5 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 PVD21713.1 - 2.7e-19 69.8 0.0 3.7e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DoxX PF07681.12 PVD21713.1 - 0.41 11.3 0.1 0.41 11.3 0.1 3.4 3 2 1 4 4 4 0 DoxX IQ PF00612.27 PVD21714.1 - 4.5e-65 209.4 409.2 0.00021 20.8 2.2 51.6 54 0 0 54 54 54 38 IQ calmodulin-binding motif ASH PF15780.5 PVD21714.1 - 2.9e-24 85.1 0.0 1.3e-23 83.0 0.0 2.3 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 PVD21714.1 - 2.9e-20 72.5 0.0 3.2e-10 40.1 0.0 4.0 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD21714.1 - 2.1e-11 43.5 0.1 1.6e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 PVD21714.1 - 1.8e-05 24.8 0.0 0.38 10.9 0.0 4.5 4 0 0 4 4 4 2 CH-like domain in sperm protein TMEM131_like PF12371.8 PVD21714.1 - 0.02 15.1 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 Transmembrane protein 131-like FIT1_2 PF17357.2 PVD21714.1 - 0.056 13.5 0.5 0.21 11.7 0.5 2.0 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Leader_Trp PF08255.11 PVD21714.1 - 0.54 10.3 3.8 2.6 8.2 0.3 3.2 2 0 0 2 2 2 0 Trp-operon Leader Peptide Ctr PF04145.15 PVD21715.1 - 5.7e-24 85.4 1.2 7.7e-24 85.0 1.2 1.2 1 0 0 1 1 1 1 Ctr copper transporter family MAPEG PF01124.18 PVD21716.1 - 3e-22 78.9 0.5 3.5e-22 78.7 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Pkinase_Tyr PF07714.17 PVD21718.1 - 8.4e-74 248.1 0.2 1.5e-72 244.1 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD21718.1 - 1.6e-34 119.5 0.0 5.8e-33 114.4 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 PVD21718.1 - 2e-11 44.1 2.0 5.8e-06 26.5 0.0 2.6 3 0 0 3 3 3 2 F5/8 type C domain EphA2_TM PF14575.6 PVD21718.1 - 0.0025 18.7 0.0 0.0063 17.4 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD21718.1 - 0.0041 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 PVD21718.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.11 PVD21718.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Protocadherin DUF5305 PF17231.2 PVD21718.1 - 0.016 14.6 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 PVD21718.1 - 0.031 14.2 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 PVD21718.1 - 0.034 14.5 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) BatD PF13584.6 PVD21718.1 - 0.08 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Cadherin_C_2 PF16492.5 PVD21718.1 - 0.12 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal F5_F8_type_C PF00754.25 PVD21720.1 - 4.9e-06 26.7 0.0 5.1e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain DUF3519 PF12033.8 PVD21721.1 - 0.13 12.6 0.5 0.13 12.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Meiosis_expr PF15163.6 PVD21723.1 - 0.029 15.1 0.6 0.04 14.6 0.6 1.3 1 0 0 1 1 1 0 Meiosis-expressed EF-hand_6 PF13405.6 PVD21728.1 - 6.8e-12 44.3 8.3 0.00018 21.1 0.2 4.1 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD21728.1 - 1.9e-11 44.2 11.2 3.4e-08 33.8 4.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD21728.1 - 2.2e-11 42.5 8.5 2e-05 23.8 0.1 3.8 3 1 1 4 4 4 3 EF hand EF-hand_5 PF13202.6 PVD21728.1 - 8e-07 28.3 13.4 0.00017 21.0 0.1 4.0 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD21728.1 - 9.9e-07 28.5 8.6 0.012 15.4 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD21728.1 - 0.00066 20.0 1.0 7.5 6.9 0.0 3.2 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region DIX PF00778.17 PVD21728.1 - 0.032 14.1 0.2 0.16 11.8 0.2 2.1 1 1 1 2 2 2 0 DIX domain EF-hand_4 PF12763.7 PVD21728.1 - 0.13 12.2 0.2 0.63 10.0 0.1 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD21729.1 - 9.6e-15 53.0 2.3 2.3e-05 23.6 1.0 4.6 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD21729.1 - 2.3e-10 40.8 9.6 0.00042 20.7 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD21729.1 - 5.3e-09 35.2 4.2 9.1e-05 21.8 0.3 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD21729.1 - 4.4e-08 32.4 17.8 0.00018 21.1 1.5 5.4 5 1 1 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 PVD21729.1 - 5.4e-05 23.0 3.8 0.28 11.1 0.6 3.8 2 1 1 3 3 3 2 EF-hand domain pair Myc_N PF01056.18 PVD21729.1 - 0.022 14.7 0.3 0.036 14.0 0.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SF3a60_bindingd PF12108.8 PVD21729.1 - 1.8 8.6 4.6 7.2 6.6 1.0 3.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain EF-hand_7 PF13499.6 PVD21730.1 - 2.1e-15 56.9 15.9 4.6e-05 23.8 1.3 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD21730.1 - 4.7e-13 47.7 17.7 0.011 15.2 2.1 6.2 6 1 1 7 7 7 5 EF hand EF-hand_6 PF13405.6 PVD21730.1 - 3.8e-12 45.1 25.2 0.04 13.8 1.7 6.9 6 1 1 7 7 7 5 EF-hand domain EF-hand_5 PF13202.6 PVD21730.1 - 1.9e-07 30.3 13.5 0.076 12.5 0.2 6.1 6 1 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 PVD21730.1 - 3.8e-05 23.4 14.5 0.012 15.4 1.0 5.4 5 1 1 6 6 6 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD21730.1 - 0.0034 17.7 10.3 0.83 10.0 0.1 4.5 1 1 3 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region UPAR_LY6_2 PF16975.5 PVD21731.1 - 0.0002 21.5 1.1 0.00048 20.3 1.1 1.6 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 PVD21731.1 - 0.034 14.8 3.3 0.094 13.4 3.3 1.8 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 PVD21731.1 - 0.088 13.1 3.6 0.19 12.0 3.6 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Spermine_synth PF01564.17 PVD21731.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Vps52 PF04129.12 PVD21732.1 - 1.1e-182 608.3 8.8 1.3e-163 545.4 6.8 2.3 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 PVD21732.1 - 8.3e-13 47.6 16.8 1.3e-10 40.4 11.6 2.3 1 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.11 PVD21732.1 - 0.00022 21.3 5.5 0.00052 20.1 3.1 2.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 SHE3 PF17078.5 PVD21732.1 - 0.35 10.6 10.2 0.33 10.6 4.7 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Ribosomal_S13 PF00416.22 PVD21733.1 - 6.9e-47 159.0 2.1 7.8e-47 158.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 PVD21733.1 - 0.2 12.1 2.7 0.18 12.3 1.3 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Gln-synt_C PF00120.24 PVD21734.1 - 3e-16 59.4 0.0 9.1e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 PVD21736.1 - 6.1e-59 199.4 3.3 8.9e-59 198.9 3.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD21736.1 - 6.9e-49 166.0 3.4 9.9e-49 165.5 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Gln-synt_C PF00120.24 PVD21736.1 - 3e-18 65.9 0.0 2.1e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain KR PF08659.10 PVD21736.1 - 5.9e-17 62.2 2.7 9.7e-17 61.5 2.7 1.3 1 0 0 1 1 1 1 KR domain Gln-synt_N PF03951.19 PVD21736.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain 3Beta_HSD PF01073.19 PVD21736.1 - 0.0016 17.5 1.2 0.0036 16.4 1.2 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PVD21736.1 - 0.0025 17.3 1.1 0.0038 16.7 0.3 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Kelch_1 PF01344.25 PVD21737.1 - 4.2e-40 135.1 9.3 1.9e-11 43.4 0.1 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 PVD21737.1 - 2.4e-27 94.3 1.0 4.9e-09 36.1 0.0 4.4 2 1 2 4 4 4 4 Kelch motif Kelch_3 PF13415.6 PVD21737.1 - 5.9e-17 61.5 10.5 1.1e-08 35.1 0.0 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD21737.1 - 4.9e-15 55.3 0.1 0.00013 21.9 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD21737.1 - 1.2e-12 47.6 5.1 0.15 12.1 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 PVD21737.1 - 4.6e-11 42.2 2.4 0.059 13.4 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Gln-synt_C PF00120.24 PVD21738.1 - 5.1e-14 52.0 0.0 2.7e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain WEMBL PF05701.11 PVD21739.1 - 0.0021 16.8 29.0 0.0031 16.3 29.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Cep57_CLD_2 PF14197.6 PVD21739.1 - 0.015 15.4 16.2 0.015 15.4 16.2 3.2 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 LPP PF04728.13 PVD21739.1 - 0.039 14.3 2.5 0.039 14.3 2.5 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper HALZ PF02183.18 PVD21739.1 - 0.047 13.9 22.7 0.42 10.9 0.5 5.1 4 1 1 5 5 5 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 PVD21739.1 - 0.3 11.3 25.7 0.61 10.3 2.5 4.9 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 PVD21739.1 - 0.8 9.9 39.2 0.021 15.0 12.0 3.3 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 PVD21739.1 - 0.99 10.1 28.4 0.32 11.6 13.7 3.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 PVD21739.1 - 1.4 7.4 9.9 1.9 7.0 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 PVD21739.1 - 1.7 9.1 20.7 0.1 13.0 2.2 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.6 PVD21739.1 - 2.3 7.5 33.9 1.1 8.6 16.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PVD21739.1 - 2.5 6.9 29.4 0.84 8.5 20.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 PVD21739.1 - 2.8 8.4 32.0 1.8 8.9 13.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 PVD21739.1 - 3.7 7.9 23.4 0.5 10.7 2.2 3.3 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF1043 PF06295.12 PVD21739.1 - 5.1 7.1 13.1 0.057 13.4 3.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DivIC PF04977.15 PVD21739.1 - 5.8 6.8 22.6 0.24 11.2 3.7 4.1 3 1 1 4 4 4 0 Septum formation initiator DUF1843 PF08898.10 PVD21739.1 - 9.3 6.8 6.7 18 5.9 0.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) adh_short_C2 PF13561.6 PVD21740.1 - 4.5e-63 212.9 0.2 5.3e-63 212.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD21740.1 - 2.2e-50 170.9 0.8 2.9e-50 170.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD21740.1 - 5.4e-10 39.5 0.2 7e-10 39.1 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD21740.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.12 PVD21740.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein DNA_methylase PF00145.17 PVD21741.1 - 3.4e-50 171.3 0.0 5.7e-49 167.3 0.0 2.7 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 PVD21741.1 - 1.5e-29 102.3 1.6 4.5e-16 58.8 0.8 2.9 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 PVD21741.1 - 9.9e-27 93.7 0.0 2e-24 86.3 0.0 2.6 1 1 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain zf-CXXC PF02008.20 PVD21741.1 - 1.4e-11 44.3 22.6 1.4e-11 44.3 22.6 3.4 3 0 0 3 3 3 1 CXXC zinc finger domain DMAP_binding PF06464.11 PVD21741.1 - 3.8e-11 43.8 1.5 8.7e-06 26.5 0.0 3.6 2 1 1 3 3 3 2 DMAP1-binding Domain RabGAP-TBC PF00566.18 PVD21742.1 - 9e-55 185.6 0.9 2.1e-54 184.4 0.9 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 PVD21742.1 - 2.6e-28 99.6 0.2 1.8e-27 96.9 0.0 2.6 2 2 0 2 2 2 1 Kinesin protein PID PF00640.23 PVD21742.1 - 5.8e-07 29.6 0.0 5.8e-07 29.6 0.0 2.7 2 1 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD21742.1 - 0.00096 19.3 0.0 0.0033 17.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotyrosine-binding domain NPV_P10 PF05531.12 PVD21742.1 - 5.2 7.6 6.0 3.2 8.3 0.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tubulin PF00091.25 PVD21743.1 - 0 1827.8 0.0 1.2e-52 179.0 0.0 14.0 5 2 9 14 14 14 14 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD21743.1 - 2.3e-39 135.0 0.0 0.0054 16.4 0.0 10.4 10 0 0 10 10 10 10 Tubulin domain DUF1484 PF07363.11 PVD21743.1 - 1.8e-12 48.2 0.0 9 7.4 0.0 9.6 9 0 0 9 9 9 2 Protein of unknown function (DUF1484) Phage_DNA_bind PF02303.17 PVD21743.1 - 8.5e-11 42.0 11.1 21 5.4 0.0 12.3 13 0 0 13 13 13 2 Helix-destabilising protein PDZ PF00595.24 PVD21746.1 - 3.1e-41 139.6 3.4 1.5e-14 54.1 0.2 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 PVD21746.1 - 2e-33 114.0 4.9 1.4e-11 44.1 0.3 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 PVD21746.1 - 6.5e-18 64.8 1.8 1.4e-05 25.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 PVD21746.1 - 1.3e-05 25.0 1.9 0.82 9.7 0.1 3.8 3 0 0 3 3 3 3 Tricorn protease PDZ domain CCM2_C PF16545.5 PVD21746.1 - 0.0042 17.6 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology Lung_7-TM_R PF06814.13 PVD21747.1 - 7e-75 252.0 15.8 1e-74 251.5 15.8 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1275 PF06912.11 PVD21747.1 - 4.5 7.2 8.7 1 9.3 3.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1275) UbiA PF01040.18 PVD21747.1 - 5.6 6.2 18.3 0.17 11.2 7.9 2.2 1 1 1 2 2 2 0 UbiA prenyltransferase family EF-hand_7 PF13499.6 PVD21748.1 - 1.4e-16 60.7 0.5 1.6e-16 60.5 0.5 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD21748.1 - 2.3e-15 54.9 4.9 5.3e-08 31.9 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD21748.1 - 4e-14 51.3 1.9 9.8e-08 31.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD21748.1 - 2.9e-10 39.2 2.3 6e-06 25.5 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD21748.1 - 1.5e-06 27.9 1.6 2.7e-05 23.9 0.4 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 PVD21748.1 - 0.0013 18.7 0.7 0.32 11.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 PVD21748.1 - 0.029 14.3 0.5 1.8 8.5 0.1 2.0 1 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 PVD21748.1 - 0.033 14.5 0.7 1.5 9.2 0.5 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ABC2_membrane_3 PF12698.7 PVD21750.1 - 2.4e-60 204.5 49.4 2.6e-43 148.5 23.6 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 PVD21750.1 - 2.4e-52 177.1 0.0 1.2e-27 97.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PVD21750.1 - 1.6e-16 61.0 0.1 6.6e-06 26.1 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PVD21750.1 - 0.001 19.7 0.7 0.27 12.0 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 PVD21750.1 - 0.0061 17.1 2.6 0.43 11.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 PVD21750.1 - 0.025 14.3 1.9 3 7.4 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain SRP54 PF00448.22 PVD21750.1 - 0.041 13.5 2.6 3 7.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 PVD21750.1 - 0.1 12.4 0.8 1 9.1 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_29 PF13555.6 PVD21750.1 - 0.14 11.9 0.9 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 PVD21750.1 - 2.7 7.2 21.1 0.0057 16.0 7.6 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein TGT PF01702.18 PVD21751.1 - 9.8e-77 258.5 0.0 1.3e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1722 PF08349.11 PVD21751.1 - 0.11 12.8 0.0 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) RRM_1 PF00076.22 PVD21752.1 - 1.2e-09 37.8 0.1 1.2e-09 37.8 0.1 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PVD21752.1 - 2.7e-08 33.7 0.1 4.7e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PVD21752.1 - 0.00091 19.2 2.6 0.0029 17.6 0.2 2.3 2 0 0 2 2 2 1 RNA binding motif DUF1866 PF08952.11 PVD21752.1 - 0.042 13.7 0.2 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Calcipressin PF04847.12 PVD21752.1 - 0.054 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Calcipressin DUF4523 PF15023.6 PVD21752.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) zf-MYND PF01753.18 PVD21753.1 - 7.5e-09 35.5 10.1 1.3e-08 34.7 10.1 1.4 1 0 0 1 1 1 1 MYND finger DUF234 PF03008.14 PVD21753.1 - 0.15 12.5 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function SRAP PF02586.14 PVD21754.1 - 1.2e-23 83.8 0.2 9.6e-17 61.2 0.0 2.9 2 1 1 3 3 3 2 SOS response associated peptidase (SRAP) Pkinase_Tyr PF07714.17 PVD21755.1 - 1.1e-66 224.8 0.0 1.5e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD21755.1 - 2.5e-26 92.6 0.0 3.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD21755.1 - 0.00054 19.4 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FixQ PF05545.11 PVD21755.1 - 0.44 10.6 1.8 11 6.0 0.3 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ fn3 PF00041.21 PVD21757.1 - 0.00084 19.6 1.2 0.012 16.0 0.4 3.2 2 1 0 2 2 2 1 Fibronectin type III domain Pkinase_Tyr PF07714.17 PVD21758.1 - 2.5e-51 174.5 0.1 2.8e-51 174.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD21758.1 - 8e-23 81.1 0.0 1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD21758.1 - 4e-05 23.1 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_7 PF16367.5 PVD21759.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Cofilin_ADF PF00241.20 PVD21760.1 - 3.9e-34 117.1 0.0 1.2e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein bZIP_1 PF00170.21 PVD21761.1 - 1.4e-14 53.9 13.1 4.1e-14 52.4 13.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor Sulfotransfer_3 PF13469.6 PVD21761.1 - 3.1e-08 34.3 0.0 8.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD21761.1 - 4.6e-07 29.6 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain bZIP_2 PF07716.15 PVD21761.1 - 4.1e-06 26.8 13.1 4.1e-06 26.8 13.1 2.9 3 1 1 4 4 4 1 Basic region leucine zipper DUF2205 PF10224.9 PVD21761.1 - 0.018 15.0 2.9 0.047 13.7 2.9 1.7 1 0 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 PVD21761.1 - 0.12 12.2 7.6 0.096 12.5 4.5 2.3 2 0 0 2 2 2 0 Septum formation initiator PsaL PF02605.15 PVD21761.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DUF4047 PF13256.6 PVD21761.1 - 0.7 10.1 3.6 0.57 10.4 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) TSC22 PF01166.18 PVD21761.1 - 0.89 9.9 4.0 10 6.5 4.1 2.4 1 1 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 PVD21761.1 - 7.9 7.2 9.5 0.3 11.7 2.8 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Mur_ligase_M PF08245.12 PVD21765.1 - 3.8e-05 23.8 0.0 0.00019 21.5 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 PVD21765.1 - 0.0041 17.4 0.0 0.0079 16.4 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain RFC1 PF08519.12 PVD21765.1 - 0.074 13.2 0.0 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Mur_ligase_M PF08245.12 PVD21766.1 - 2.4e-12 47.2 0.1 0.00013 22.0 0.1 3.7 2 2 1 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 PVD21766.1 - 9.1e-08 32.3 0.0 0.026 14.8 0.0 2.6 2 0 0 2 2 2 2 Mur ligase family, glutamate ligase domain RFC1 PF08519.12 PVD21766.1 - 0.0088 16.2 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain SecE PF00584.20 PVD21766.1 - 0.0094 15.9 0.1 2.4 8.2 0.0 2.8 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex Sel1 PF08238.12 PVD21766.1 - 0.013 16.2 0.0 3.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat DNA_mis_repair PF01119.19 PVD21766.1 - 0.094 12.4 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain AnfG_VnfG PF03139.15 PVD21766.1 - 0.15 12.1 0.0 9.8 6.3 0.0 3.0 2 1 1 3 3 3 0 Vanadium/alternative nitrogenase delta subunit mTERF PF02536.14 PVD21766.1 - 0.17 10.8 0.0 27 3.5 0.0 2.9 3 0 0 3 3 3 0 mTERF NRIP1_repr_2 PF15688.5 PVD21766.1 - 0.19 11.6 0.0 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 2 V-set PF07686.17 PVD21767.1 - 6.3e-06 26.3 2.3 0.00059 20.0 0.1 3.4 3 0 0 3 3 3 1 Immunoglobulin V-set domain AAA_30 PF13604.6 PVD21767.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PVD21767.1 - 0.0044 17.5 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD21767.1 - 0.031 14.6 0.0 0.13 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 PVD21767.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD21767.1 - 0.059 13.6 0.6 0.26 11.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD21767.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 PVD21767.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ig_3 PF13927.6 PVD21767.1 - 0.13 12.9 0.1 0.13 12.9 0.1 3.6 5 1 0 5 5 5 0 Immunoglobulin domain MobB PF03205.14 PVD21767.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 PVD21767.1 - 0.22 11.7 0.6 0.95 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD21768.1 - 1.1e-08 35.3 0.0 1.4e-05 25.2 0.0 2.8 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA PF00004.29 PVD21768.1 - 3.4e-06 27.5 0.0 0.021 15.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PVD21768.1 - 7.4e-05 22.6 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PVD21768.1 - 0.00012 22.5 1.2 0.11 12.9 0.2 3.5 2 2 0 2 2 2 2 AAA ATPase domain Cobl PF09469.10 PVD21768.1 - 0.0023 18.1 0.1 0.75 10.1 0.0 3.4 3 0 0 3 3 3 1 Cordon-bleu ubiquitin-like domain AAA_22 PF13401.6 PVD21768.1 - 0.0035 17.6 0.1 0.55 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PVD21768.1 - 0.012 16.0 1.9 5.3 7.5 0.0 3.9 4 1 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 PVD21768.1 - 0.012 15.3 0.0 2.9 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PVD21768.1 - 0.021 14.3 0.8 4 6.8 0.0 3.5 3 1 0 3 3 3 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 PVD21768.1 - 0.062 12.9 0.1 11 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 PVD21768.1 - 0.099 13.2 0.1 15 6.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain WAP PF00095.21 PVD21769.1 - 2.3e-09 37.5 31.6 1.1e-08 35.3 13.4 3.3 3 0 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lectin_C PF00059.21 PVD21769.1 - 1.3e-06 29.1 0.0 2.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain zf-C3HC4_3 PF13920.6 PVD21770.1 - 2.5e-09 36.8 9.6 2.5e-09 36.8 9.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21770.1 - 2.7e-09 36.7 8.5 2.7e-09 36.7 8.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD21770.1 - 2.4e-08 34.0 14.3 5e-05 23.4 4.2 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD21770.1 - 2.9e-08 33.9 9.6 2.9e-08 33.9 9.6 3.3 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD21770.1 - 4.5e-08 32.8 12.1 4.5e-08 32.8 12.1 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD21770.1 - 1.9e-06 27.6 9.7 1.9e-06 27.6 9.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21770.1 - 3.5e-06 27.1 8.9 3.5e-06 27.1 8.9 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD21770.1 - 7.7e-06 25.8 11.6 7.7e-06 25.8 11.6 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD21770.1 - 0.00045 20.1 10.3 0.00045 20.1 10.3 3.3 3 1 0 3 3 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD21770.1 - 0.0037 17.3 3.5 0.0037 17.3 3.5 3.1 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.6 PVD21771.1 - 7.4e-12 44.9 28.4 2.6e-09 36.8 11.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21771.1 - 2e-09 37.2 8.7 2e-09 37.2 8.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD21771.1 - 4.3e-09 36.5 9.5 4.3e-09 36.5 9.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD21771.1 - 2.1e-08 34.1 7.4 2.1e-08 34.1 7.4 2.7 2 2 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD21771.1 - 1e-07 31.6 10.1 1e-07 31.6 10.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD21771.1 - 1.3e-07 31.3 12.7 1.3e-07 31.3 12.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD21771.1 - 9.5e-06 25.7 6.7 9.5e-06 25.7 6.7 4.2 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD21771.1 - 1.7e-05 24.8 8.6 1.7e-05 24.8 8.6 2.8 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD21771.1 - 3.2e-05 23.8 10.3 3.2e-05 23.8 10.3 3.1 2 1 1 3 3 1 1 zinc-RING finger domain ArfGap PF01412.18 PVD21771.1 - 0.00024 21.1 15.2 0.00078 19.5 5.0 2.2 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf zf-RING_10 PF16685.5 PVD21771.1 - 7.5 6.8 26.5 0.21 11.7 8.6 2.5 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 PVD21772.1 - 2.3e-12 46.6 27.2 3e-10 39.8 5.4 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21772.1 - 2.7e-10 39.9 6.1 2.7e-10 39.9 6.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD21772.1 - 2e-09 37.6 7.6 2e-09 37.6 7.6 3.3 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 PVD21772.1 - 2.1e-09 37.1 6.3 2.1e-09 37.1 6.3 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD21772.1 - 1.5e-07 31.3 7.4 1.5e-07 31.3 7.4 4.0 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD21772.1 - 1.8e-07 30.9 7.6 1.8e-07 30.9 7.6 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21772.1 - 8e-06 25.9 7.4 8e-06 25.9 7.4 3.7 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD21772.1 - 3.8e-05 23.6 4.9 3.8e-05 23.6 4.9 4.1 3 2 2 5 5 4 1 zinc-RING finger domain zf-B_box PF00643.24 PVD21772.1 - 0.00026 21.1 9.6 0.00026 21.1 9.6 3.2 2 1 0 2 2 2 1 B-box zinc finger ArfGap PF01412.18 PVD21772.1 - 0.023 14.8 18.0 0.027 14.6 6.6 2.8 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf EDR1 PF14381.6 PVD21772.1 - 0.04 13.6 1.4 0.087 12.5 0.4 1.9 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Orthopox_B11R PF07033.11 PVD21772.1 - 0.061 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Baculo_PEP_C PF04513.12 PVD21772.1 - 0.16 12.0 3.9 0.35 10.9 3.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Neuralized PF07177.12 PVD21773.1 - 5.3e-13 49.2 0.0 8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Neuralized zf-C3HC4 PF00097.25 PVD21773.1 - 2.2e-11 43.4 6.6 5.9e-11 42.0 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21773.1 - 3.8e-11 42.7 5.9 9.2e-11 41.4 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD21773.1 - 2.1e-10 40.3 6.0 4.6e-10 39.2 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD21773.1 - 7.6e-10 39.0 7.8 7.6e-10 39.0 7.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD21773.1 - 9.5e-09 35.2 5.4 9.5e-09 35.2 5.4 3.2 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD21773.1 - 2.6e-08 33.6 7.7 2.6e-08 33.6 7.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21773.1 - 2.1e-06 27.8 7.7 4.6e-06 26.7 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD21773.1 - 0.00011 22.1 9.6 0.00025 20.9 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD21773.1 - 0.00084 19.6 6.4 0.0021 18.3 6.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PVD21773.1 - 0.0012 18.8 4.8 0.03 14.4 0.6 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPRY PF00622.28 PVD21773.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 SPRY domain zf-RING_11 PF17123.5 PVD21773.1 - 0.035 13.9 4.0 0.15 11.8 4.0 2.2 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 PVD21773.1 - 0.093 12.9 4.0 0.18 11.9 4.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 PVD21773.1 - 0.25 11.1 8.1 0.22 11.4 5.1 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PVD21773.1 - 0.27 10.9 7.6 0.31 10.7 6.4 1.7 1 1 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 PVD21773.1 - 0.33 10.6 5.3 0.81 9.4 5.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type I-set PF07679.16 PVD21774.1 - 4.1e-10 39.6 2.9 0.036 14.1 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21774.1 - 7.6e-05 23.2 20.9 0.2 12.3 0.2 5.7 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 PVD21774.1 - 0.00011 22.3 22.6 0.043 14.0 0.1 4.8 5 0 0 5 5 5 3 Immunoglobulin V-set domain Insulin_TMD PF17870.1 PVD21774.1 - 0.01 15.9 3.2 1.9 8.6 0.5 2.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment ig PF00047.25 PVD21774.1 - 0.086 13.0 7.1 6.8 6.9 0.1 4.2 4 0 0 4 4 4 0 Immunoglobulin domain SirB PF04247.12 PVD21774.1 - 0.12 12.5 1.5 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB AAA_19 PF13245.6 PVD21775.1 - 0.016 15.5 0.0 0.073 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD21775.1 - 0.061 13.7 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 PVD21775.1 - 0.064 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 PVD21775.1 - 0.074 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 PVD21775.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PVD21775.1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 PVD21775.1 - 2.9 7.3 7.1 9.8 5.5 0.1 4.2 4 1 0 4 4 4 0 Chromatin associated protein KTI12 NERD PF08378.11 PVD21776.1 - 0.008 16.6 0.1 0.024 15.1 0.1 1.8 1 0 0 1 1 1 1 Nuclease-related domain FTCD_C PF04961.12 PVD21776.1 - 0.02 14.6 0.8 0.21 11.3 0.2 2.5 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase V-set PF07686.17 PVD21777.1 - 2.6e-26 91.9 43.6 0.00053 20.1 0.1 9.0 8 0 0 8 8 8 6 Immunoglobulin V-set domain AAA_16 PF13191.6 PVD21777.1 - 1.1e-19 71.5 0.1 0.0086 16.5 0.0 6.9 6 1 0 6 6 6 4 AAA ATPase domain AAA PF00004.29 PVD21777.1 - 1.5e-18 67.5 0.0 0.0058 17.1 0.0 6.9 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PVD21777.1 - 2.6e-18 66.5 0.0 0.0097 15.6 0.0 6.4 6 0 0 6 6 6 5 AAA domain AAA_19 PF13245.6 PVD21777.1 - 6.7e-17 62.2 0.0 0.017 15.4 0.0 7.0 7 0 0 7 7 6 4 AAA domain Ig_3 PF13927.6 PVD21777.1 - 4.1e-16 59.3 42.0 0.0063 17.1 0.7 9.6 8 0 0 8 8 8 5 Immunoglobulin domain I-set PF07679.16 PVD21777.1 - 2.3e-14 53.2 20.3 0.011 15.8 0.0 9.0 8 0 0 8 8 8 4 Immunoglobulin I-set domain AAA_22 PF13401.6 PVD21777.1 - 3e-11 43.7 0.3 0.081 13.2 0.0 6.0 6 0 0 6 6 6 2 AAA domain AAA_5 PF07728.14 PVD21777.1 - 3.2e-10 40.1 5.0 0.06 13.4 0.0 6.2 6 0 0 6 6 6 2 AAA domain (dynein-related subfamily) ig PF00047.25 PVD21777.1 - 1.2e-08 34.9 38.9 0.019 15.1 0.5 9.1 8 0 0 8 8 8 3 Immunoglobulin domain ATPase_2 PF01637.18 PVD21777.1 - 2.2e-08 34.3 0.0 0.15 12.0 0.0 5.6 5 0 0 5 5 5 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 PVD21777.1 - 2.6e-08 33.8 0.0 0.14 11.9 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_11 PF13086.6 PVD21777.1 - 2e-07 31.1 8.9 0.022 14.6 0.0 6.9 7 1 0 7 7 7 1 AAA domain TMEM154 PF15102.6 PVD21777.1 - 8.2e-07 29.0 5.0 0.0043 17.0 0.2 4.8 4 0 0 4 4 4 1 TMEM154 protein family AAA_7 PF12775.7 PVD21777.1 - 6.4e-06 25.8 0.1 1.2 8.6 0.0 5.6 7 0 0 7 7 5 1 P-loop containing dynein motor region RuvB_N PF05496.12 PVD21777.1 - 1.4e-05 24.9 0.4 5.5 6.7 0.0 5.4 6 0 0 6 6 5 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 PVD21777.1 - 4.2e-05 23.2 0.1 21 4.6 0.0 6.1 6 0 0 6 6 6 0 AAA domain Helicase_RecD PF05127.14 PVD21777.1 - 8e-05 22.6 0.1 4.1 7.2 0.0 4.5 4 0 0 4 4 4 0 Helicase AAA_18 PF13238.6 PVD21777.1 - 0.0002 21.9 1.7 15 6.1 0.0 5.9 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.12 PVD21777.1 - 0.00061 19.1 0.0 2.3 7.5 0.0 4.5 5 0 0 5 5 5 1 Zeta toxin PhoH PF02562.16 PVD21777.1 - 0.00062 19.3 0.0 1.6 8.2 0.0 4.5 5 0 0 5 5 5 1 PhoH-like protein SRP54 PF00448.22 PVD21777.1 - 0.00066 19.4 0.2 0.35 10.5 0.1 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 PVD21777.1 - 0.0018 18.0 0.6 25 4.5 0.0 5.0 6 0 0 6 6 4 0 AAA domain Mg_chelatase PF01078.21 PVD21777.1 - 0.0027 17.1 0.9 2 7.8 0.0 4.6 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PVD21777.1 - 0.0028 17.8 0.4 65 3.7 0.0 5.7 4 1 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 PVD21777.1 - 0.003 17.9 3.3 36 4.8 0.0 5.9 6 0 0 6 6 5 0 RNA helicase NTPase_1 PF03266.15 PVD21777.1 - 0.0033 17.3 4.8 7.3 6.5 0.0 5.5 6 0 0 6 6 5 0 NTPase ResIII PF04851.15 PVD21777.1 - 0.0056 16.7 0.4 0.87 9.6 0.1 4.0 5 0 0 5 5 2 1 Type III restriction enzyme, res subunit EphA2_TM PF14575.6 PVD21777.1 - 0.0064 17.3 10.7 0.63 11.0 0.1 4.8 5 0 0 5 5 4 1 Ephrin type-A receptor 2 transmembrane domain Speriolin_C PF15059.6 PVD21777.1 - 0.0072 16.5 0.3 20 5.3 0.0 4.6 5 0 0 5 5 3 0 Speriolin C-terminus DAG1 PF05454.11 PVD21777.1 - 0.0073 15.7 2.7 0.14 11.5 0.3 3.0 3 0 0 3 3 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CHDNT PF08073.12 PVD21777.1 - 0.018 15.0 1.2 82 3.3 0.0 5.7 6 0 0 6 6 4 0 CHDNT (NUC034) domain Ig_2 PF13895.6 PVD21777.1 - 0.024 15.0 48.8 6 7.3 0.3 9.9 7 1 1 8 8 8 0 Immunoglobulin domain AAA_28 PF13521.6 PVD21777.1 - 0.026 14.8 0.1 19 5.5 0.0 3.7 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 PVD21777.1 - 0.032 14.1 0.1 25 4.8 0.0 3.9 3 0 0 3 3 3 0 NACHT domain Tetraspanin PF00335.20 PVD21777.1 - 0.035 13.8 10.6 4.8 6.8 0.2 5.2 6 0 0 6 6 5 0 Tetraspanin family Vpu PF00558.19 PVD21777.1 - 0.053 13.3 4.3 12 5.7 1.8 3.6 2 0 0 2 2 2 0 Vpu protein Cadherin_C_2 PF16492.5 PVD21777.1 - 0.06 14.1 3.7 0.51 11.1 0.0 3.9 4 0 0 4 4 3 0 Cadherin cytoplasmic C-terminal DUF4448 PF14610.6 PVD21777.1 - 0.061 13.1 0.2 5.4 6.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) FAM176 PF14851.6 PVD21777.1 - 0.14 11.8 0.2 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 FAM176 family MotA_ExbB PF01618.16 PVD21777.1 - 0.16 11.7 0.3 1.8 8.3 0.0 3.0 3 0 0 3 3 2 0 MotA/TolQ/ExbB proton channel family Izumo-Ig PF16706.5 PVD21777.1 - 0.17 12.0 4.7 45 4.2 0.0 6.0 8 0 0 8 8 4 0 Izumo-like Immunoglobulin domain DC_STAMP PF07782.13 PVD21777.1 - 1 9.1 5.1 0.53 10.1 1.5 2.4 2 0 0 2 2 2 0 DC-STAMP-like protein DUF4577 PF15145.6 PVD21777.1 - 1.3 9.1 6.2 0.52 10.4 0.1 3.4 4 0 0 4 4 2 0 Domain of unknown function (DUF4577) FtsL PF04999.13 PVD21777.1 - 3.1 7.8 9.6 0.55 10.3 0.5 3.4 3 0 0 3 3 3 0 Cell division protein FtsL RIFIN PF02009.16 PVD21777.1 - 3.8 7.3 16.8 0.59 10.0 0.3 4.1 5 0 0 5 5 3 0 Rifin DUF4326 PF14216.6 PVD21777.1 - 9.6 7.0 8.0 44 4.9 0.7 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) EphA2_TM PF14575.6 PVD21778.1 - 0.013 16.4 0.2 0.036 14.9 0.2 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 PVD21778.1 - 0.014 15.2 1.4 0.032 14.0 1.4 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Shisa PF13908.6 PVD21778.1 - 0.027 14.7 0.4 0.049 13.9 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RAMP PF04901.13 PVD21778.1 - 0.03 14.3 0.3 0.11 12.5 0.2 2.0 1 1 0 1 1 1 0 Receptor activity modifying family TMEM154 PF15102.6 PVD21778.1 - 0.031 14.2 0.4 0.031 14.2 0.4 1.8 2 0 0 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 PVD21778.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 PVD21778.1 - 0.22 11.5 2.4 0.12 12.3 0.4 1.6 2 0 0 2 2 2 0 Protocadherin AAA_16 PF13191.6 PVD21779.1 - 1.6e-07 31.9 0.0 3.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PVD21779.1 - 1e-05 26.0 0.0 2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD21779.1 - 0.0046 17.0 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD21779.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD21779.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PVD21779.1 - 0.047 14.0 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD21779.1 - 0.073 12.6 0.0 0.41 10.1 0.0 1.9 1 1 1 2 2 2 0 P-loop containing dynein motor region KdpD PF02702.17 PVD21779.1 - 0.085 12.3 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain RuvB_N PF05496.12 PVD21779.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PVD21779.1 - 0.11 12.6 0.2 6.1 7.0 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PVD21779.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NERD PF08378.11 PVD21780.1 - 0.0068 16.8 0.1 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 Nuclease-related domain AAA_30 PF13604.6 PVD21781.1 - 2.2e-10 40.6 0.0 0.014 15.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PVD21781.1 - 5.5e-10 39.8 0.0 0.11 12.9 0.1 3.7 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 PVD21781.1 - 7.3e-09 36.2 0.0 0.082 13.3 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 PVD21781.1 - 3.4e-07 30.7 0.2 0.26 11.7 0.1 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PVD21781.1 - 4.6e-05 23.2 0.0 3.3 7.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein V-set PF07686.17 PVD21781.1 - 7.9e-05 22.8 20.9 0.00025 21.2 0.2 5.3 5 0 0 5 5 5 1 Immunoglobulin V-set domain AAA_5 PF07728.14 PVD21781.1 - 0.00017 21.6 0.4 4.7 7.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD21781.1 - 0.00024 21.4 0.1 4.9 7.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 PVD21781.1 - 0.00036 20.2 0.0 1.7 8.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain EphA2_TM PF14575.6 PVD21781.1 - 0.0011 19.8 0.1 2.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain AAA_24 PF13479.6 PVD21781.1 - 0.002 17.9 0.1 8.9 6.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain Ly49 PF08391.10 PVD21781.1 - 0.0022 18.4 0.2 0.33 11.3 0.0 3.3 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region AAA_7 PF12775.7 PVD21781.1 - 0.0027 17.3 0.0 5.6 6.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region I-set PF07679.16 PVD21781.1 - 0.0055 16.8 3.2 1.4 9.0 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain PhoH PF02562.16 PVD21781.1 - 0.0063 16.0 0.0 3.1 7.2 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein RNA_helicase PF00910.22 PVD21781.1 - 0.0075 16.6 0.2 28 5.2 0.1 3.9 3 0 0 3 3 3 0 RNA helicase MLANA PF14991.6 PVD21781.1 - 0.008 16.4 0.0 5.4 7.3 0.0 3.0 2 0 0 2 2 2 1 Protein melan-A AAA_18 PF13238.6 PVD21781.1 - 0.009 16.6 0.2 18 5.9 0.0 4.3 4 0 0 4 4 3 0 AAA domain Helicase_RecD PF05127.14 PVD21781.1 - 0.011 15.6 0.0 2.9 7.7 0.0 3.2 3 0 0 3 3 3 0 Helicase ResIII PF04851.15 PVD21781.1 - 0.013 15.6 0.0 9 6.3 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF4381 PF14316.6 PVD21781.1 - 0.014 15.7 0.1 2.1 8.6 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4381) NTPase_1 PF03266.15 PVD21781.1 - 0.036 14.0 0.1 4.5 7.2 0.0 3.0 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 PVD21781.1 - 0.048 12.9 0.0 1.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 PVD21781.1 - 0.066 13.0 14.5 0.083 12.7 0.0 4.4 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 PVD21781.1 - 0.079 13.1 0.3 57 3.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 PVD21781.1 - 0.11 12.7 0.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PVD21781.1 - 0.14 12.1 0.0 16 5.4 0.0 2.9 2 0 0 2 2 2 0 NACHT domain zf-CHCC PF10276.9 PVD21781.1 - 0.7 10.0 3.0 7 6.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain Marek_A PF02124.15 PVD21781.1 - 0.88 9.4 6.3 0.37 10.6 0.1 3.5 5 0 0 5 5 5 0 Marek's disease glycoprotein A CAAP1 PF15335.6 PVD21781.1 - 1.1 9.8 3.3 3.9 8.1 0.4 3.2 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 TMEM252 PF15664.5 PVD21781.1 - 4.5 7.0 5.4 1.4 8.6 0.1 2.7 4 0 0 4 4 2 0 Transmembrane protein 252 family V-set PF07686.17 PVD21782.1 - 0.0043 17.2 1.4 0.5 10.6 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain GrpB PF04229.14 PVD21782.1 - 0.006 16.8 0.4 3.2 7.9 0.1 2.6 2 0 0 2 2 2 2 GrpB protein Sgf11 PF08209.11 PVD21782.1 - 0.01 15.4 3.1 3.3 7.3 0.0 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) AAA_19 PF13245.6 PVD21782.1 - 0.072 13.4 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 PVD21782.1 - 0.076 13.3 2.3 14 6.1 0.1 3.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ig_3 PF13927.6 PVD21782.1 - 0.24 12.0 2.8 1.1 10.0 0.4 2.8 2 0 0 2 2 2 0 Immunoglobulin domain DUF3963 PF13124.6 PVD21782.1 - 0.35 10.9 7.2 12 5.9 3.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) zf-CHCC PF10276.9 PVD21782.1 - 0.89 9.7 4.4 3.9 7.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger domain DUF5627 PF18620.1 PVD21782.1 - 2.9 7.7 9.0 0.52 10.2 0.7 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5627) IstB_IS21 PF01695.17 PVD21783.1 - 7.8e-06 25.7 0.0 0.058 13.1 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.6 PVD21783.1 - 1.4e-05 24.9 0.0 0.0083 15.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PVD21783.1 - 5.9e-05 23.4 0.0 1.3 9.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 PVD21783.1 - 0.00018 22.0 0.0 0.33 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PVD21783.1 - 0.00023 21.6 0.0 0.49 10.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 PVD21783.1 - 0.00084 19.2 0.2 0.32 10.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PVD21783.1 - 0.0029 17.9 0.1 7.1 6.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 PVD21783.1 - 0.0069 16.3 0.0 3.3 7.5 0.0 2.6 2 0 0 2 2 2 1 Helicase AAA_5 PF07728.14 PVD21783.1 - 0.032 14.3 0.1 1.9 8.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MCM PF00493.23 PVD21783.1 - 0.047 12.8 0.0 2.6 7.1 0.0 3.0 3 0 0 3 3 3 0 MCM P-loop domain TRM PF02005.16 PVD21783.1 - 0.048 12.8 0.8 0.45 9.6 0.0 2.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase AAA_18 PF13238.6 PVD21783.1 - 0.053 14.1 0.1 1.7 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain V-set PF07686.17 PVD21783.1 - 0.065 13.4 0.1 0.065 13.4 0.1 4.8 5 0 0 5 5 4 0 Immunoglobulin V-set domain GCFC PF07842.12 PVD21783.1 - 0.12 11.9 2.5 0.76 9.3 0.2 2.9 3 0 0 3 3 3 0 GC-rich sequence DNA-binding factor-like protein ABC_tran PF00005.27 PVD21783.1 - 0.15 12.6 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 PVD21783.1 - 0.16 11.7 0.4 10 5.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain BatA PF07584.11 PVD21783.1 - 0.31 11.4 0.5 59 4.1 0.0 3.8 5 0 0 5 5 3 0 Aerotolerance regulator N-terminal DUF3482 PF11981.8 PVD21783.1 - 0.44 9.9 2.3 2.6 7.3 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3482) ig PF00047.25 PVD21783.1 - 0.54 10.5 6.8 7.5 6.8 0.2 4.0 3 0 0 3 3 3 0 Immunoglobulin domain DUF5627 PF18620.1 PVD21783.1 - 0.78 9.6 3.0 7.9 6.4 0.7 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5627) Ig_3 PF13927.6 PVD21783.1 - 2.9 8.5 9.7 25 5.6 0.1 4.9 4 0 0 4 4 4 0 Immunoglobulin domain Rax2 PF12768.7 PVD21783.1 - 3.2 7.2 5.1 7.1 6.0 0.0 3.5 4 1 1 5 5 5 0 Cortical protein marker for cell polarity V-set PF07686.17 PVD21784.1 - 5.5e-09 36.2 2.7 0.00042 20.5 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain AAA PF00004.29 PVD21784.1 - 6.3e-08 33.1 0.0 0.08 13.4 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD21784.1 - 8.3e-08 32.8 0.0 0.093 13.1 0.0 3.8 3 0 0 3 3 3 3 AAA ATPase domain AAA_5 PF07728.14 PVD21784.1 - 1.7e-05 24.9 0.1 0.23 11.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Ig_3 PF13927.6 PVD21784.1 - 2e-05 25.1 7.1 0.3 11.7 0.2 4.5 3 0 0 3 3 3 2 Immunoglobulin domain AAA_30 PF13604.6 PVD21784.1 - 4.7e-05 23.2 0.0 1.8 8.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain TK PF00265.18 PVD21784.1 - 0.00011 22.2 0.1 0.93 9.3 0.0 3.3 4 0 0 4 4 3 2 Thymidine kinase HemY_N PF07219.13 PVD21784.1 - 0.0014 18.8 4.9 0.093 12.9 0.1 3.0 3 0 0 3 3 3 2 HemY protein N-terminus AAA_19 PF13245.6 PVD21784.1 - 0.0044 17.4 0.0 8 6.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 PVD21784.1 - 0.0049 17.1 0.0 0.34 11.2 0.0 3.6 4 0 0 4 4 3 1 AAA domain I-set PF07679.16 PVD21784.1 - 0.0068 16.4 0.2 28 4.8 0.1 3.6 3 0 0 3 3 3 0 Immunoglobulin I-set domain AAA_25 PF13481.6 PVD21784.1 - 0.026 14.1 0.0 6.6 6.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain RSN1_TM PF13967.6 PVD21784.1 - 0.029 14.1 2.8 5.1 6.8 0.1 2.8 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport TMEM154 PF15102.6 PVD21784.1 - 0.034 14.1 4.2 1.7 8.5 0.2 4.2 5 0 0 5 5 4 0 TMEM154 protein family EphA2_TM PF14575.6 PVD21784.1 - 0.072 14.0 2.6 4.4 8.3 0.1 3.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ig PF00047.25 PVD21784.1 - 0.097 12.9 9.5 5.2 7.3 0.4 4.1 4 0 0 4 4 3 0 Immunoglobulin domain Speriolin_C PF15059.6 PVD21784.1 - 0.097 12.8 1.0 28 4.8 0.0 4.2 3 1 0 3 3 3 0 Speriolin C-terminus DC_STAMP PF07782.13 PVD21784.1 - 0.1 12.4 7.2 0.063 13.1 0.3 3.2 3 0 0 3 3 3 0 DC-STAMP-like protein Sigma70_r1_1 PF03979.14 PVD21784.1 - 0.11 12.6 0.6 6.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 CAAP1 PF15335.6 PVD21784.1 - 0.13 12.9 6.8 2.8 8.6 0.2 3.7 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 LPG_synthase_TM PF03706.13 PVD21784.1 - 0.15 11.6 0.0 84 2.5 0.0 3.1 3 0 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region DUF2681 PF10883.8 PVD21784.1 - 0.3 11.5 1.9 9.9 6.7 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RcsD_ABL PF16359.5 PVD21784.1 - 0.44 10.7 1.9 83 3.4 0.0 3.8 3 0 0 3 3 3 0 RcsD-ABL domain LapA_dom PF06305.11 PVD21784.1 - 1.6 8.6 5.7 3.2 7.6 0.1 2.7 3 0 0 3 3 2 0 Lipopolysaccharide assembly protein A domain YhfH PF14149.6 PVD21784.1 - 3.4 7.7 6.1 99 3.0 0.1 3.7 3 0 0 3 3 3 0 YhfH-like protein V-set PF07686.17 PVD21785.1 - 9.4e-10 38.6 4.4 2.6e-05 24.4 0.2 3.3 3 0 0 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 PVD21785.1 - 3.8e-06 26.9 3.2 0.0058 16.7 0.1 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21785.1 - 6.7e-05 23.4 7.7 0.058 14.0 0.2 3.4 3 0 0 3 3 3 2 Immunoglobulin domain AAA_30 PF13604.6 PVD21785.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD21785.1 - 0.00033 21.0 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TMEM154 PF15102.6 PVD21785.1 - 0.00062 19.7 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family ig PF00047.25 PVD21785.1 - 0.0016 18.6 4.9 0.077 13.2 1.1 3.0 2 0 0 2 2 2 1 Immunoglobulin domain SRP54 PF00448.22 PVD21785.1 - 0.0017 18.0 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 PVD21785.1 - 0.0024 18.3 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PVD21785.1 - 0.0034 17.8 0.0 0.008 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PVD21785.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RIFIN PF02009.16 PVD21785.1 - 0.021 14.8 0.4 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Rifin AAA_22 PF13401.6 PVD21785.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD21785.1 - 0.056 14.0 0.1 0.33 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PVD21785.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PVD21785.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 PVD21785.1 - 0.077 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EpoR_lig-bind PF09067.10 PVD21785.1 - 3.9 7.7 7.9 14 6.0 0.4 3.8 1 1 2 3 3 3 0 Erythropoietin receptor, ligand binding Phage_Coat_B PF05356.11 PVD21786.1 - 0.17 11.8 2.2 0.28 11.1 0.9 2.1 2 0 0 2 2 2 0 Phage Coat protein B AAA_16 PF13191.6 PVD21787.1 - 2.1e-07 31.5 0.1 5.4e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PVD21787.1 - 8.6e-06 26.2 0.1 2.3e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD21787.1 - 0.0018 18.6 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD21787.1 - 0.0037 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PVD21787.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Beta_protein PF14350.6 PVD21787.1 - 0.01 15.3 0.1 0.058 12.8 0.0 1.9 2 0 0 2 2 2 0 Beta protein AAA_7 PF12775.7 PVD21787.1 - 0.012 15.1 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 PVD21787.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PVD21787.1 - 0.026 14.7 0.2 4.5 7.4 0.5 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD21787.1 - 0.043 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 PVD21787.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 PVD21787.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 PVD21787.1 - 0.11 12.4 0.2 0.47 10.4 0.1 1.9 1 1 1 2 2 2 0 NTPase KdpD PF02702.17 PVD21787.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_18 PF13238.6 PVD21787.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD21787.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 PVD21788.1 - 1.9e-05 25.1 0.0 4.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD21788.1 - 5.3e-05 23.7 0.1 0.00016 22.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PVD21788.1 - 0.00098 19.4 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD21788.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PVD21788.1 - 0.0091 15.9 0.2 0.025 14.5 0.2 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 PVD21788.1 - 0.0092 16.3 0.1 0.039 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD21788.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PVD21788.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NERD PF08378.11 PVD21788.1 - 0.031 14.7 0.3 0.062 13.8 0.3 1.5 1 0 0 1 1 1 0 Nuclease-related domain ATPase_2 PF01637.18 PVD21788.1 - 0.035 14.0 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 PVD21788.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 PVD21788.1 - 0.07 12.9 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 PVD21788.1 - 0.077 12.7 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 PVD21788.1 - 0.081 12.7 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 PVD21788.1 - 0.099 12.6 0.1 2.1 8.3 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 PVD21788.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HOIP-UBA PF16678.5 PVD21788.1 - 0.19 11.8 0.2 0.44 10.5 0.0 1.7 2 0 0 2 2 2 0 HOIP UBA domain pair TMEM154 PF15102.6 PVD21789.1 - 2.6e-05 24.2 0.1 4.4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 PVD21789.1 - 0.0037 17.1 0.6 0.009 15.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 PVD21789.1 - 0.0049 17.7 0.2 0.013 16.4 0.2 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.17 PVD21789.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin V-set domain PRIMA1 PF16101.5 PVD21789.1 - 0.017 15.1 0.3 0.043 13.9 0.1 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DAG1 PF05454.11 PVD21789.1 - 0.039 13.3 0.1 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ig_3 PF13927.6 PVD21789.1 - 0.056 14.1 0.2 0.14 12.7 0.2 1.7 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 PVD21789.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set_2 PF15910.5 PVD21789.1 - 0.082 13.0 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 ICOS V-set domain EF-G-binding_N PF07299.11 PVD21789.1 - 0.085 13.4 0.3 15 6.2 0.0 2.9 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF3377 PF11857.8 PVD21789.1 - 0.09 12.7 8.2 0.13 12.2 7.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) ig PF00047.25 PVD21789.1 - 0.098 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF4381 PF14316.6 PVD21789.1 - 0.23 11.7 0.0 0.44 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Insulin_TMD PF17870.1 PVD21789.1 - 1.9 8.6 7.6 0.66 10.1 2.5 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment AAA_19 PF13245.6 PVD21790.1 - 0.00017 22.0 0.2 0.00069 20.0 0.0 2.1 3 1 0 3 3 3 1 AAA domain V-set PF07686.17 PVD21790.1 - 0.00026 21.2 0.1 0.00062 19.9 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain AAA_30 PF13604.6 PVD21790.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD21790.1 - 0.0022 18.4 0.1 0.0076 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF4381 PF14316.6 PVD21790.1 - 0.0057 16.9 0.1 0.078 13.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) AAA PF00004.29 PVD21790.1 - 0.0062 17.0 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PVD21790.1 - 0.022 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 PVD21790.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 PVD21790.1 - 0.074 12.8 0.2 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PVD21790.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 PVD21791.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD21791.1 - 0.0027 18.1 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mid2 PF04478.12 PVD21791.1 - 0.0049 16.7 0.0 0.0049 16.7 0.0 2.0 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor AAA_16 PF13191.6 PVD21791.1 - 0.016 15.6 0.0 0.1 12.9 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Protocadherin PF08374.11 PVD21791.1 - 0.085 12.8 0.1 0.085 12.8 0.1 1.9 2 0 0 2 2 2 0 Protocadherin Ly49 PF08391.10 PVD21791.1 - 0.19 12.1 1.5 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region FAM176 PF14851.6 PVD21791.1 - 0.82 9.3 8.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 FAM176 family V-set PF07686.17 PVD21793.1 - 0.59 10.3 4.5 2.6 8.3 2.6 2.5 2 0 0 2 2 2 0 Immunoglobulin V-set domain V-set PF07686.17 PVD21794.1 - 6.5e-07 29.5 8.6 0.048 13.8 0.1 4.5 4 1 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 PVD21794.1 - 0.0006 19.9 6.9 2 8.6 0.1 4.6 4 0 0 4 4 4 2 Immunoglobulin domain TMEM252 PF15664.5 PVD21794.1 - 0.0064 16.2 0.9 4.3 7.1 0.0 2.7 2 0 0 2 2 2 2 Transmembrane protein 252 family Poxvirus_B22R_N PF13169.6 PVD21794.1 - 0.084 13.4 3.9 7.5 7.1 0.4 2.9 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal Ig_3 PF13927.6 PVD21794.1 - 0.1 13.2 6.8 14 6.4 0.0 4.4 4 0 0 4 4 4 0 Immunoglobulin domain DUF3920 PF13058.6 PVD21794.1 - 0.12 12.6 2.3 15 5.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3920) ICAM_N PF03921.14 PVD21794.1 - 0.13 12.0 4.2 1.1 8.9 0.6 3.1 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain LolA_like PF17131.4 PVD21794.1 - 0.32 10.7 3.0 4.5 7.0 0.7 3.5 4 0 0 4 4 4 0 Outer membrane lipoprotein-sorting protein DUF5627 PF18620.1 PVD21794.1 - 0.78 9.6 8.7 5.6 6.8 0.5 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5627) Auxin_resp PF06507.13 PVD21795.1 - 0.078 13.2 0.1 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Auxin response factor UBA_3 PF09288.10 PVD21795.1 - 0.085 12.7 0.1 2 8.3 0.0 2.6 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain AAA_30 PF13604.6 PVD21796.1 - 1.1e-17 64.5 0.0 0.0019 17.9 0.0 4.5 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.6 PVD21796.1 - 1.7e-14 54.5 0.0 0.029 14.7 0.0 4.6 4 0 0 4 4 4 4 AAA ATPase domain AAA PF00004.29 PVD21796.1 - 1.2e-13 51.7 0.0 0.075 13.5 0.0 4.7 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PVD21796.1 - 1.2e-13 51.2 0.0 0.011 15.4 0.0 4.5 4 0 0 4 4 4 3 IstB-like ATP binding protein AAA_19 PF13245.6 PVD21796.1 - 1.8e-11 44.6 0.0 0.42 10.9 0.0 4.6 4 0 0 4 4 4 3 AAA domain AAA_5 PF07728.14 PVD21796.1 - 2.7e-10 40.4 0.1 0.061 13.3 0.0 4.5 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 PVD21796.1 - 5.6e-09 36.1 0.0 0.97 9.3 0.0 5.0 5 0 0 5 5 5 2 Helicase MeaB PF03308.16 PVD21796.1 - 1.1e-08 34.5 0.2 0.44 9.5 0.0 4.3 4 0 0 4 4 4 3 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 PVD21796.1 - 1.1e-08 35.2 2.1 1.2 8.9 0.0 4.9 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 PVD21796.1 - 1.1e-08 35.6 0.5 2.4 8.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 PVD21796.1 - 1.5e-08 34.4 0.0 2.8 7.4 0.0 4.9 4 1 1 5 5 5 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 PVD21796.1 - 9.1e-08 31.6 0.0 0.62 9.3 0.0 4.5 4 0 0 4 4 4 1 Zeta toxin PSRP-3_Ycf65 PF04839.13 PVD21796.1 - 1.1e-07 32.0 0.7 1.9 8.8 0.0 4.9 4 0 0 4 4 4 1 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) ABC_tran PF00005.27 PVD21796.1 - 2.9e-07 31.1 0.0 9.5 6.7 0.0 4.9 4 0 0 4 4 4 0 ABC transporter AAA_24 PF13479.6 PVD21796.1 - 7.3e-07 29.1 1.2 3.7 7.2 0.0 4.7 4 0 0 4 4 4 1 AAA domain V-set PF07686.17 PVD21796.1 - 1.2e-06 28.7 22.0 0.084 13.1 0.1 6.8 7 0 0 7 7 6 3 Immunoglobulin V-set domain AAA_22 PF13401.6 PVD21796.1 - 1.3e-06 28.7 0.1 5.8 7.2 0.0 5.0 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 PVD21796.1 - 1.8e-06 27.7 0.0 0.68 9.5 0.0 4.2 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain NACHT PF05729.12 PVD21796.1 - 2.4e-06 27.5 0.1 0.14 12.0 0.0 4.5 4 0 0 4 4 4 1 NACHT domain Ig_3 PF13927.6 PVD21796.1 - 4.8e-06 27.1 17.4 0.22 12.1 0.1 6.2 5 1 0 5 5 5 3 Immunoglobulin domain TRM PF02005.16 PVD21796.1 - 2e-05 24.0 2.4 0.24 10.5 0.1 3.7 3 0 0 3 3 3 1 N2,N2-dimethylguanosine tRNA methyltransferase RNA_helicase PF00910.22 PVD21796.1 - 4.2e-05 23.9 0.4 18 5.8 0.0 4.7 4 0 0 4 4 4 0 RNA helicase NTPase_1 PF03266.15 PVD21796.1 - 5.7e-05 23.1 1.4 0.73 9.7 0.0 4.3 4 0 0 4 4 4 1 NTPase I-set PF07679.16 PVD21796.1 - 0.00013 22.0 0.1 3.9 7.6 0.0 4.5 4 0 0 4 4 4 1 Immunoglobulin I-set domain AAA_28 PF13521.6 PVD21796.1 - 0.00023 21.4 3.4 22 5.2 0.0 4.8 4 0 0 4 4 4 0 AAA domain MCM PF00493.23 PVD21796.1 - 0.00039 19.6 0.0 8.4 5.4 0.0 4.0 4 0 0 4 4 4 0 MCM P-loop domain AAA_29 PF13555.6 PVD21796.1 - 0.00073 19.2 0.0 8.7 6.2 0.0 4.3 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA_25 PF13481.6 PVD21796.1 - 0.0012 18.5 1.0 11 5.6 0.0 4.9 6 0 0 6 6 4 0 AAA domain VirE PF05272.11 PVD21796.1 - 0.0085 15.8 0.0 31 4.2 0.0 4.4 4 0 0 4 4 4 0 Virulence-associated protein E PhoH PF02562.16 PVD21796.1 - 0.012 15.1 0.0 15 4.9 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein ig PF00047.25 PVD21796.1 - 0.014 15.5 4.3 2.7 8.2 0.0 4.6 4 0 0 4 4 3 0 Immunoglobulin domain Mg_chelatase PF01078.21 PVD21796.1 - 0.027 13.9 0.4 23 4.3 0.0 3.7 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 PVD21796.1 - 0.027 13.6 0.6 31 3.6 0.0 4.1 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 PSII_BNR PF14870.6 PVD21796.1 - 0.041 13.1 1.1 6.2 6.0 0.0 3.0 3 0 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 CUE PF02845.16 PVD21796.1 - 0.15 11.8 0.0 66 3.3 0.0 3.9 4 0 0 4 4 3 0 CUE domain KTI12 PF08433.10 PVD21796.1 - 0.17 11.3 2.1 2.7 7.4 0.0 3.7 4 0 0 4 4 4 0 Chromatin associated protein KTI12 UPF0004 PF00919.20 PVD21796.1 - 0.4 10.8 7.8 42 4.3 0.0 5.6 6 0 0 6 6 5 0 Uncharacterized protein family UPF0004 Gram_pos_anchor PF00746.21 PVD21796.1 - 1.6 8.7 8.6 9.4 6.3 1.3 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif ATP_bind_1 PF03029.17 PVD21796.1 - 2 8.1 4.1 2.2e+02 1.5 0.1 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 PVD21796.1 - 5.9 7.0 6.7 94 3.1 0.1 4.1 4 0 0 4 4 4 0 AAA domain Phage_int_SAM_2 PF12834.7 PVD21797.1 - 0.0012 19.5 2.5 0.0069 17.0 0.1 3.0 4 0 0 4 4 4 1 Phage integrase, N-terminal AAA_16 PF13191.6 PVD21797.1 - 0.02 15.3 0.0 0.072 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 PVD21797.1 - 0.023 14.0 0.3 4.1 6.7 0.1 3.1 4 0 0 4 4 4 0 KaiC AAA_18 PF13238.6 PVD21797.1 - 0.042 14.4 0.1 0.27 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain V-set PF07686.17 PVD21799.1 - 0.00097 19.3 0.2 0.0073 16.5 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD21799.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD21799.1 - 0.086 13.4 0.1 0.33 11.6 0.1 2.0 1 0 0 1 1 1 0 Immunoglobulin domain AAA_16 PF13191.6 PVD21800.1 - 1.2e-13 51.8 0.5 0.12 12.8 0.0 4.6 4 0 0 4 4 4 4 AAA ATPase domain AAA_30 PF13604.6 PVD21800.1 - 4.6e-12 46.1 0.0 0.0032 17.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 PVD21800.1 - 4.3e-10 40.1 0.0 0.0039 17.5 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 PVD21800.1 - 8.8e-09 35.9 0.1 0.092 13.2 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PVD21800.1 - 8e-07 28.8 0.1 0.97 9.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain V-set PF07686.17 PVD21800.1 - 6.1e-06 26.4 14.9 0.00036 20.7 0.4 5.0 5 0 0 5 5 4 2 Immunoglobulin V-set domain IstB_IS21 PF01695.17 PVD21800.1 - 9.9e-06 25.4 0.0 1.1 9.0 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 PVD21800.1 - 1.1e-05 24.8 0.0 3.5 6.9 0.0 4.6 4 0 0 4 4 4 2 Zeta toxin AAA_22 PF13401.6 PVD21800.1 - 2e-05 24.9 0.6 0.21 11.9 0.0 4.5 5 0 0 5 5 4 1 AAA domain Ig_3 PF13927.6 PVD21800.1 - 2.2e-05 25.0 11.5 0.044 14.4 0.4 4.3 3 0 0 3 3 3 2 Immunoglobulin domain PhoH PF02562.16 PVD21800.1 - 3.2e-05 23.5 0.0 0.85 9.0 0.0 4.5 5 0 0 5 5 5 1 PhoH-like protein I-set PF07679.16 PVD21800.1 - 3.5e-05 23.8 4.7 0.12 12.4 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin I-set domain AAA_11 PF13086.6 PVD21800.1 - 0.00023 21.0 0.9 2.6 7.8 0.0 4.4 4 0 0 4 4 4 2 AAA domain Meth_synt_2 PF01717.18 PVD21800.1 - 0.00024 20.5 0.0 0.37 10.0 0.0 2.6 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain AAA_PrkA PF08298.11 PVD21800.1 - 0.002 17.1 0.0 0.77 8.6 0.0 3.3 3 0 0 3 3 3 1 PrkA AAA domain AAA_5 PF07728.14 PVD21800.1 - 0.0027 17.7 2.1 4 7.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PVD21800.1 - 0.0029 18.1 0.1 36 4.9 0.0 4.7 4 0 0 4 4 4 0 AAA domain SRPRB PF09439.10 PVD21800.1 - 0.0044 16.5 1.1 7.9 5.9 0.0 4.6 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 PVD21800.1 - 0.01 15.6 0.3 43 3.7 0.0 4.5 4 1 0 4 4 4 0 AAA domain MeaB PF03308.16 PVD21800.1 - 0.02 13.9 0.0 18 4.2 0.0 4.1 5 0 0 5 5 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 PVD21800.1 - 0.061 13.2 0.2 35 4.3 0.0 3.7 4 0 0 4 4 4 0 NTPase Coatomer_g_Cpla PF16381.5 PVD21800.1 - 0.064 13.4 0.2 14 5.9 0.0 3.6 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform Phage_holin_6_1 PF09682.10 PVD21800.1 - 0.12 12.8 0.8 27 5.3 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ribosomal_L31 PF01197.18 PVD21800.1 - 0.12 12.6 1.8 18 5.6 0.1 4.0 3 1 1 4 4 4 0 Ribosomal protein L31 Mg_chelatase PF01078.21 PVD21800.1 - 0.47 9.8 2.6 51 3.1 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI FdsD PF11390.8 PVD21800.1 - 1.1 9.6 4.4 1.3e+02 3.0 0.0 4.3 4 0 0 4 4 4 0 NADH-dependant formate dehydrogenase delta subunit FdsD ig PF00047.25 PVD21800.1 - 2.7 8.2 10.2 0.86 9.8 0.3 3.8 3 0 0 3 3 3 0 Immunoglobulin domain PP2C_C PF07830.13 PVD21800.1 - 3.3 8.2 7.4 18 5.9 0.7 3.4 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain IL6Ra-bind PF09240.10 PVD21800.1 - 7.2 7.1 10.9 5.2 7.6 1.5 4.0 3 0 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding Ig_3 PF13927.6 PVD21801.1 - 5.6e-07 30.1 1.3 0.024 15.2 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD21801.1 - 1.5e-05 25.0 0.2 0.27 11.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD21801.1 - 0.00089 19.4 0.4 0.26 11.5 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD21801.1 - 0.083 13.1 0.7 18 5.6 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21801.1 - 0.11 12.6 0.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD21801.1 - 0.15 11.7 3.3 0.4 10.3 0.0 3.0 4 0 0 4 4 4 0 Immunoglobulin domain V-set PF07686.17 PVD21802.1 - 0.018 15.2 1.2 0.068 13.3 0.2 2.5 3 1 0 3 3 3 0 Immunoglobulin V-set domain NHR2 PF08788.11 PVD21802.1 - 0.065 13.0 0.3 10 5.9 0.0 3.1 2 0 0 2 2 2 0 NHR2 domain like MotA_ExbB PF01618.16 PVD21802.1 - 0.29 10.9 1.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family GIT1_C PF12205.8 PVD21802.1 - 0.88 9.7 3.5 4.8 7.3 0.0 3.9 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term Sulfatase PF00884.23 PVD21803.1 - 1.9e-49 168.7 1.3 2e-15 57.0 0.0 4.8 3 2 2 5 5 5 4 Sulfatase Phosphodiest PF01663.22 PVD21803.1 - 2.3e-09 37.3 0.1 0.0016 18.1 0.0 3.4 2 2 2 4 4 4 2 Type I phosphodiesterase / nucleotide pyrophosphatase TraQ PF09679.10 PVD21803.1 - 0.011 15.6 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) UPF0180 PF03698.13 PVD21803.1 - 0.022 14.9 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) AAA_30 PF13604.6 PVD21803.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ig_3 PF13927.6 PVD21804.1 - 0.00021 21.9 0.5 0.11 13.1 0.1 3.2 2 1 0 2 2 2 1 Immunoglobulin domain AAA_16 PF13191.6 PVD21804.1 - 0.00051 20.5 0.0 0.0021 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain I-set PF07679.16 PVD21804.1 - 0.00063 19.8 0.1 0.37 10.9 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain AAA_30 PF13604.6 PVD21804.1 - 0.00095 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD21804.1 - 0.0031 17.8 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ninjurin PF04923.12 PVD21804.1 - 0.0052 16.7 0.4 0.011 15.7 0.4 1.4 1 0 0 1 1 1 1 Ninjurin Izumo-Ig PF16706.5 PVD21804.1 - 0.0073 16.3 0.0 8.5 6.5 0.0 3.1 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain AAA_19 PF13245.6 PVD21804.1 - 0.0074 16.6 0.0 0.038 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ig PF00047.25 PVD21804.1 - 0.0077 16.4 0.6 5.1 7.4 0.1 3.2 3 1 0 3 3 3 1 Immunoglobulin domain SRP54 PF00448.22 PVD21804.1 - 0.016 14.8 0.0 1.3 8.6 0.0 2.3 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain TK PF00265.18 PVD21804.1 - 0.023 14.6 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Thymidine kinase V-set PF07686.17 PVD21804.1 - 0.04 14.1 1.1 5.4 7.2 0.1 3.2 2 1 1 3 3 3 0 Immunoglobulin V-set domain Leader_CPA1 PF08252.11 PVD21804.1 - 0.061 12.7 2.1 0.064 12.7 0.1 2.1 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide MeaB PF03308.16 PVD21804.1 - 0.065 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 PVD21804.1 - 0.075 12.9 0.8 0.22 11.4 0.1 2.2 2 1 0 2 2 2 0 NTPase AAA_25 PF13481.6 PVD21804.1 - 0.25 10.9 1.4 0.9 9.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 PVD21804.1 - 0.42 10.8 1.4 5.3 7.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain I-set PF07679.16 PVD21805.1 - 8.4e-09 35.4 0.2 0.071 13.2 0.1 3.5 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21805.1 - 1.3e-08 35.3 4.5 0.025 15.2 0.8 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD21805.1 - 5.7e-07 29.7 1.5 0.045 13.9 0.1 4.4 2 1 2 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 PVD21805.1 - 0.00012 22.2 6.2 1.7 8.9 1.1 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21805.1 - 0.0004 20.4 0.2 14 5.8 0.0 4.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain SKG6 PF08693.10 PVD21805.1 - 0.00096 18.5 3.0 0.0022 17.3 3.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ig_2 PF13895.6 PVD21805.1 - 0.0098 16.2 8.3 0.96 9.8 1.9 3.7 2 2 1 3 3 3 2 Immunoglobulin domain Ninjurin PF04923.12 PVD21805.1 - 0.011 15.6 0.5 0.023 14.6 0.5 1.4 1 0 0 1 1 1 0 Ninjurin TMEM154 PF15102.6 PVD21805.1 - 0.021 14.7 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family IL6Ra-bind PF09240.10 PVD21805.1 - 0.04 14.4 6.7 12 6.4 0.4 3.7 2 1 1 3 3 3 0 Interleukin-6 receptor alpha chain, binding Leader_CPA1 PF08252.11 PVD21805.1 - 0.047 13.1 2.1 0.062 12.7 0.1 2.3 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide DUF3377 PF11857.8 PVD21805.1 - 0.067 13.1 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Speriolin_C PF15059.6 PVD21805.1 - 0.14 12.3 0.0 0.49 10.5 0.0 2.0 1 0 0 1 1 1 0 Speriolin C-terminus Adeno_E3_CR2 PF02439.15 PVD21805.1 - 0.22 11.3 1.0 0.48 10.2 1.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 V-set PF07686.17 PVD21806.1 - 1e-07 32.1 4.0 0.00043 20.4 0.5 3.7 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD21806.1 - 2.9e-07 31.0 5.4 0.019 15.5 0.7 3.9 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD21806.1 - 7.3e-07 29.2 0.3 0.25 11.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD21806.1 - 1.6e-05 25.0 4.8 0.69 10.1 0.3 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21806.1 - 0.031 14.3 3.6 47 4.1 0.0 4.9 5 1 0 5 5 5 0 Izumo-like Immunoglobulin domain SKG6 PF08693.10 PVD21806.1 - 0.037 13.4 1.7 0.085 12.3 1.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Leader_CPA1 PF08252.11 PVD21806.1 - 0.052 12.9 0.1 0.052 12.9 0.1 2.2 3 0 0 3 3 3 0 arg-2/CPA1 leader peptide Ig_2 PF13895.6 PVD21806.1 - 0.099 13.0 13.8 1.4 9.4 4.0 4.2 3 2 0 3 3 3 0 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 PVD21806.1 - 0.19 11.5 1.5 0.45 10.3 1.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IL6Ra-bind PF09240.10 PVD21806.1 - 1 9.8 5.1 7.8 7.0 0.8 3.5 3 0 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding V-set PF07686.17 PVD21807.1 - 8.1e-08 32.4 4.3 0.099 12.8 0.1 4.9 4 0 0 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.16 PVD21807.1 - 3.9e-07 30.1 1.7 0.11 12.5 0.1 4.6 3 1 1 4 4 4 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD21807.1 - 1.4e-06 28.8 13.8 0.023 15.3 0.6 5.5 5 0 0 5 5 5 2 Immunoglobulin domain Leader_CPA1 PF08252.11 PVD21807.1 - 3.8e-06 26.2 0.9 0.13 11.7 0.1 3.0 2 0 0 2 2 2 2 arg-2/CPA1 leader peptide ig PF00047.25 PVD21807.1 - 1.9e-05 24.8 16.5 0.17 12.1 0.6 5.2 5 0 0 5 5 5 3 Immunoglobulin domain SRP54 PF00448.22 PVD21807.1 - 0.00099 18.8 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Izumo-Ig PF16706.5 PVD21807.1 - 0.0011 19.0 3.3 1.8 8.7 0.0 5.7 4 1 1 5 5 4 1 Izumo-like Immunoglobulin domain Speriolin_C PF15059.6 PVD21807.1 - 0.0013 18.9 0.1 3.1 7.9 0.0 3.0 2 0 0 2 2 2 2 Speriolin C-terminus CesT PF05932.13 PVD21807.1 - 0.0065 16.6 0.4 10 6.3 0.1 4.0 4 0 0 4 4 3 0 Tir chaperone protein (CesT) family AAA_30 PF13604.6 PVD21807.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ninjurin PF04923.12 PVD21807.1 - 0.017 15.1 0.2 0.042 13.8 0.2 1.6 1 0 0 1 1 1 0 Ninjurin AAA_16 PF13191.6 PVD21807.1 - 0.033 14.6 0.0 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF1279 PF06916.13 PVD21807.1 - 0.036 14.6 0.0 67 4.1 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) T2SSE_N PF05157.15 PVD21807.1 - 0.036 14.3 0.0 3.3 8.0 0.0 3.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain HisKA_3 PF07730.13 PVD21807.1 - 0.043 14.3 3.2 29 5.3 0.1 4.2 3 0 0 3 3 3 0 Histidine kinase Secretin_N PF03958.17 PVD21807.1 - 0.049 14.0 6.7 22 5.6 0.2 3.9 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain ACDC PF14733.6 PVD21807.1 - 0.06 13.7 0.7 4.9 7.5 0.1 3.4 3 0 0 3 3 3 0 AP2-coincident C-terminal Adeno_E3_CR2 PF02439.15 PVD21807.1 - 0.071 12.9 2.9 0.15 11.9 2.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_33 PF13671.6 PVD21807.1 - 0.11 12.7 2.0 4.1 7.6 0.0 4.1 3 1 1 4 4 4 0 AAA domain AAA_22 PF13401.6 PVD21807.1 - 0.12 12.7 0.5 1.4 9.2 0.1 3.0 2 0 0 2 2 2 0 AAA domain MycE_N PF17843.1 PVD21807.1 - 0.13 12.8 7.9 25 5.4 0.2 3.7 3 0 0 3 3 3 0 MycE methyltransferase N-terminal SIS_2 PF13580.6 PVD21807.1 - 0.17 11.9 0.0 37 4.3 0.0 3.0 2 0 0 2 2 2 0 SIS domain Ig_2 PF13895.6 PVD21807.1 - 1.5 9.2 14.1 1.4 9.3 1.3 4.2 3 1 1 4 4 4 0 Immunoglobulin domain COMP PF11598.8 PVD21807.1 - 2.3 8.7 8.2 47 4.6 0.1 4.3 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein DUF4349 PF14257.6 PVD21807.1 - 4 6.8 7.3 61 3.0 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) Ig_3 PF13927.6 PVD21808.1 - 3.6e-07 30.7 2.9 0.016 15.8 0.6 3.4 2 1 0 2 2 2 2 Immunoglobulin domain AAA_16 PF13191.6 PVD21808.1 - 3.2e-06 27.6 0.0 1.4e-05 25.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain V-set PF07686.17 PVD21808.1 - 4e-05 23.7 7.8 9.7e-05 22.5 0.5 3.4 3 1 0 3 3 2 1 Immunoglobulin V-set domain ig PF00047.25 PVD21808.1 - 7.6e-05 22.8 6.4 0.042 14.0 1.2 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD21808.1 - 0.00011 22.2 0.1 0.12 12.4 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain SKG6 PF08693.10 PVD21808.1 - 0.00033 20.0 1.5 0.00079 18.8 1.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AAA_30 PF13604.6 PVD21808.1 - 0.0014 18.4 0.0 0.0045 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 PVD21808.1 - 0.0031 17.8 0.9 0.013 15.8 0.2 2.3 2 1 0 2 2 1 1 AAA domain TMEM154 PF15102.6 PVD21808.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 TMEM154 protein family Ig_6 PF18452.1 PVD21808.1 - 0.013 15.1 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain AAA_19 PF13245.6 PVD21808.1 - 0.015 15.6 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ig_2 PF13895.6 PVD21808.1 - 0.02 15.2 10.5 0.62 10.4 3.9 3.9 1 1 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21808.1 - 0.024 14.7 0.8 5.2 7.2 0.0 3.6 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain Leader_CPA1 PF08252.11 PVD21808.1 - 0.041 13.3 1.6 0.057 12.8 0.1 2.0 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide MeaB PF03308.16 PVD21808.1 - 0.052 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 PVD21808.1 - 0.066 13.1 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 NTPase Marek_A PF02124.15 PVD21808.1 - 0.082 12.7 0.8 0.83 9.4 0.1 2.4 2 0 0 2 2 2 0 Marek's disease glycoprotein A Speriolin_C PF15059.6 PVD21808.1 - 0.082 13.0 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 Speriolin C-terminus Insulin_TMD PF17870.1 PVD21808.1 - 0.11 12.6 0.5 0.23 11.5 0.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 PVD21808.1 - 0.11 12.3 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_33 PF13671.6 PVD21808.1 - 0.26 11.5 1.2 7.2 6.8 0.6 3.1 2 2 0 2 2 2 0 AAA domain Tmemb_9 PF05434.11 PVD21808.1 - 0.91 9.4 4.0 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 TMEM9 AAA_11 PF13086.6 PVD21808.1 - 0.96 9.2 8.4 0.48 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF4349 PF14257.6 PVD21808.1 - 2.4 7.5 5.8 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Methyltransf_23 PF13489.6 PVD21809.1 - 0.012 15.4 0.0 2.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain UPF0242 PF06785.11 PVD21809.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ogr_Delta PF04606.12 PVD21809.1 - 0.13 12.3 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Prd1-P2 PF09214.11 PVD21809.1 - 0.21 10.3 0.1 0.3 9.8 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Methyltransf_23 PF13489.6 PVD21810.1 - 0.022 14.6 0.1 1.1 9.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ogr_Delta PF04606.12 PVD21810.1 - 0.053 13.5 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Prd1-P2 PF09214.11 PVD21810.1 - 0.16 10.7 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Neuralized PF07177.12 PVD21811.1 - 2.7e-13 50.2 0.0 6.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Neuralized zf-C3HC4_3 PF13920.6 PVD21811.1 - 2.8e-07 30.3 10.8 2.8e-07 30.3 10.8 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21811.1 - 8.4e-07 28.8 13.0 8.4e-07 28.8 13.0 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD21811.1 - 3.7e-06 26.9 13.9 3.7e-06 26.9 13.9 3.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.24 PVD21811.1 - 3.8e-06 27.0 22.0 5.4e-05 23.3 3.9 4.4 4 1 0 4 4 2 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD21811.1 - 1.4e-05 25.1 12.2 1.4e-05 25.1 12.2 3.5 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD21811.1 - 1.9e-05 24.5 12.1 1.9e-05 24.5 12.1 3.8 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD21811.1 - 3.4e-05 23.6 12.3 3.4e-05 23.6 12.3 3.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD21811.1 - 8.9e-05 22.7 12.4 8.9e-05 22.7 12.4 4.3 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 PVD21811.1 - 0.0016 18.4 11.5 0.0016 18.4 11.5 4.7 3 3 2 5 5 3 1 zinc-RING finger domain Csm1_N PF18504.1 PVD21811.1 - 0.018 15.3 1.3 0.034 14.5 0.4 1.9 2 0 0 2 2 1 0 Csm1 N-terminal domain FUSC PF04632.12 PVD21811.1 - 0.045 12.3 0.4 0.062 11.8 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PSCyt3 PF07627.11 PVD21811.1 - 0.1 12.9 2.8 1 9.7 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) DUF2225 PF09986.9 PVD21811.1 - 0.26 11.0 5.6 5.1 6.8 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2408 PF10303.9 PVD21811.1 - 0.27 11.8 9.0 2.2 8.9 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Occludin_ELL PF07303.13 PVD21811.1 - 4.4 8.1 7.1 49 4.7 0.2 3.3 2 1 1 3 3 3 0 Occludin homology domain zf-Nse PF11789.8 PVD21811.1 - 4.7 7.1 12.0 2.5 8.0 8.3 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.6 PVD21811.1 - 5.6 7.6 7.6 22 5.7 0.1 4.0 3 0 0 3 3 3 0 Zinc-finger double domain I-set PF07679.16 PVD21812.1 - 1.2e-06 28.5 0.1 0.069 13.2 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 PVD21812.1 - 1.6e-06 28.3 7.6 0.0041 17.3 0.2 3.6 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD21812.1 - 0.00018 22.1 6.7 0.091 13.4 0.1 3.9 4 0 0 4 4 4 2 Immunoglobulin domain AAA_19 PF13245.6 PVD21812.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD21812.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ig PF00047.25 PVD21812.1 - 0.0084 16.3 1.4 15 5.8 0.0 3.9 2 2 2 4 4 4 2 Immunoglobulin domain KTI12 PF08433.10 PVD21812.1 - 0.013 15.0 0.6 0.076 12.4 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 PVD21812.1 - 0.042 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD21813.1 - 8.1e-15 55.6 0.0 9.9e-05 22.8 0.0 3.7 3 0 0 3 3 3 3 AAA ATPase domain AAA_19 PF13245.6 PVD21813.1 - 1.7e-14 54.4 0.0 0.0013 19.1 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_30 PF13604.6 PVD21813.1 - 3.5e-14 53.0 0.0 0.0017 18.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.6 PVD21813.1 - 3.7e-14 53.2 0.0 2.8e-05 24.4 0.0 4.0 3 0 0 3 3 3 3 AAA domain AAA PF00004.29 PVD21813.1 - 3.8e-10 40.3 0.2 0.0091 16.4 0.0 4.0 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 PVD21813.1 - 2e-08 33.5 0.1 0.18 10.7 0.0 3.6 3 0 0 3 3 3 3 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 PVD21813.1 - 7e-08 32.6 1.2 0.35 10.8 0.0 3.9 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 PVD21813.1 - 1.6e-07 31.4 0.2 0.2 11.6 0.0 4.7 5 0 0 5 5 5 2 NTPase IstB_IS21 PF01695.17 PVD21813.1 - 4.3e-06 26.6 0.1 0.6 9.8 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein I-set PF07679.16 PVD21813.1 - 4.5e-06 26.6 0.0 0.12 12.4 0.0 3.6 3 0 0 3 3 2 2 Immunoglobulin I-set domain AAA_28 PF13521.6 PVD21813.1 - 2.3e-05 24.7 0.7 2.8 8.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain V-set PF07686.17 PVD21813.1 - 2.5e-05 24.4 6.3 0.16 12.2 0.1 4.7 5 0 0 5 5 3 2 Immunoglobulin V-set domain SRP54 PF00448.22 PVD21813.1 - 3.1e-05 23.7 0.0 2.3 7.8 0.0 3.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 PVD21813.1 - 7.9e-05 23.2 3.9 0.88 10.1 0.0 4.8 5 0 0 5 5 3 1 AAA domain AAA_24 PF13479.6 PVD21813.1 - 0.0001 22.1 0.0 5.4 6.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Ig_3 PF13927.6 PVD21813.1 - 0.00013 22.5 10.1 0.18 12.4 0.1 5.2 5 0 0 5 5 4 2 Immunoglobulin domain ABC_tran PF00005.27 PVD21813.1 - 0.00024 21.6 1.4 6.5 7.3 0.0 4.3 4 0 0 4 4 3 0 ABC transporter AAA_11 PF13086.6 PVD21813.1 - 0.00055 19.8 4.8 2.6 7.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain Marek_A PF02124.15 PVD21813.1 - 0.00091 19.1 0.3 9 6.1 0.0 3.5 3 0 0 3 3 3 0 Marek's disease glycoprotein A AAA_7 PF12775.7 PVD21813.1 - 0.0017 17.9 0.0 1.6 8.2 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region KdpD PF02702.17 PVD21813.1 - 0.0048 16.4 0.0 4 6.9 0.0 3.3 3 0 0 3 3 3 1 Osmosensitive K+ channel His kinase sensor domain TFA2_Winged_2 PF18121.1 PVD21813.1 - 0.0056 16.3 0.8 4.7 7.0 0.1 2.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 RNA_helicase PF00910.22 PVD21813.1 - 0.0063 16.9 0.1 6.6 7.2 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.12 PVD21813.1 - 0.0092 15.3 0.0 5.9 6.1 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin CUE PF02845.16 PVD21813.1 - 0.011 15.4 0.0 4.7 7.0 0.0 2.9 2 0 0 2 2 2 0 CUE domain DUF4609 PF15382.6 PVD21813.1 - 0.019 14.9 0.0 5.9 6.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4609) DUF2119 PF09892.9 PVD21813.1 - 0.02 14.3 0.2 8.1 5.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) DUF853 PF05872.12 PVD21813.1 - 0.032 12.8 0.0 16 4.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 PVD21813.1 - 0.041 14.1 1.7 9.9 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 PVD21813.1 - 0.1 12.6 5.3 27 4.7 0.0 5.0 5 1 0 5 5 4 0 Type III restriction enzyme, res subunit Nitroreductase PF00881.24 PVD21813.1 - 0.18 11.9 0.1 26 4.8 0.0 3.0 3 0 0 3 3 2 0 Nitroreductase family ig PF00047.25 PVD21813.1 - 0.45 10.7 7.7 16 5.7 0.1 4.6 5 0 0 5 5 3 0 Immunoglobulin domain AAA_19 PF13245.6 PVD21814.1 - 8.1e-12 45.7 0.0 0.007 16.7 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_30 PF13604.6 PVD21814.1 - 2.9e-11 43.4 0.0 0.028 14.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 PVD21814.1 - 1.2e-09 38.7 0.0 0.025 14.9 0.0 3.5 3 0 0 3 3 3 3 AAA ATPase domain V-set PF07686.17 PVD21814.1 - 2.1e-08 34.3 14.8 0.21 11.8 0.1 5.0 4 0 0 4 4 4 4 Immunoglobulin V-set domain AAA_22 PF13401.6 PVD21814.1 - 4e-08 33.6 0.4 6.1e-05 23.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain EphA2_TM PF14575.6 PVD21814.1 - 2e-06 28.6 0.4 0.069 14.0 0.0 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain KTI12 PF08433.10 PVD21814.1 - 5.1e-06 26.1 0.2 1 8.7 0.0 4.0 3 0 0 3 3 3 2 Chromatin associated protein KTI12 AAA_18 PF13238.6 PVD21814.1 - 5e-05 23.9 0.3 5.6 7.5 0.0 3.9 3 0 0 3 3 3 0 AAA domain I-set PF07679.16 PVD21814.1 - 5.6e-05 23.1 2.1 4.4 7.5 0.1 5.0 4 1 0 4 4 4 1 Immunoglobulin I-set domain MeaB PF03308.16 PVD21814.1 - 7.2e-05 21.9 0.0 0.051 12.6 0.0 3.2 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 PVD21814.1 - 0.00013 21.3 0.0 4.7 6.4 0.0 3.8 4 0 0 4 4 4 1 Zeta toxin TK PF00265.18 PVD21814.1 - 0.00018 21.4 0.0 0.54 10.1 0.0 2.6 2 0 0 2 2 2 2 Thymidine kinase DUF5385 PF17359.2 PVD21814.1 - 0.00025 20.7 0.3 0.052 13.1 0.1 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5385) KdpD PF02702.17 PVD21814.1 - 0.00058 19.4 0.0 1.5 8.2 0.0 3.5 3 0 0 3 3 3 1 Osmosensitive K+ channel His kinase sensor domain Izumo-Ig PF16706.5 PVD21814.1 - 0.0011 19.0 0.7 0.82 9.8 0.0 3.8 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Stevor PF17410.2 PVD21814.1 - 0.0014 18.2 0.4 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame AAA PF00004.29 PVD21814.1 - 0.0017 18.7 0.0 6 7.3 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PVD21814.1 - 0.0052 17.0 1.7 17 5.6 0.1 3.6 3 0 0 3 3 3 0 AAA domain Ig_3 PF13927.6 PVD21814.1 - 0.0055 17.3 21.0 0.36 11.5 0.7 5.7 5 1 0 5 5 4 2 Immunoglobulin domain Orf78 PF06024.12 PVD21814.1 - 0.011 16.1 0.4 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) PRESAN PF09687.10 PVD21814.1 - 0.011 16.3 6.3 1.3 9.5 0.1 3.3 3 0 0 3 3 2 0 Plasmodium RESA N-terminal 7tm_1 PF00001.21 PVD21814.1 - 0.015 14.6 0.2 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) IstB_IS21 PF01695.17 PVD21814.1 - 0.038 13.7 0.0 35 4.1 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein Marek_A PF02124.15 PVD21814.1 - 0.067 13.0 13.3 0.36 10.6 1.5 3.8 5 0 0 5 5 3 0 Marek's disease glycoprotein A TMEM154 PF15102.6 PVD21814.1 - 0.082 12.8 1.1 9.9 6.1 0.1 2.8 2 0 0 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 PVD21814.1 - 0.084 13.3 0.5 8.2 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PTPS PF01242.19 PVD21814.1 - 0.085 12.8 0.4 19 5.3 0.1 2.6 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase RIFIN PF02009.16 PVD21814.1 - 0.09 12.7 1.1 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Rifin AAA_11 PF13086.6 PVD21814.1 - 0.092 12.5 0.2 37 4.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain RCR PF12273.8 PVD21814.1 - 0.11 13.2 0.1 8.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Thiolase_N PF00108.23 PVD21814.1 - 0.14 11.5 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Baculo_11_kDa PF06143.11 PVD21814.1 - 0.64 9.6 7.4 0.68 9.6 1.1 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family ECSCR PF15820.5 PVD21814.1 - 2.1 8.2 7.4 12 5.8 1.5 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Ig_2 PF13895.6 PVD21814.1 - 9 6.7 22.5 2.2 8.7 1.9 4.9 3 2 1 4 4 4 0 Immunoglobulin domain SKG6 PF08693.10 PVD21815.1 - 8.5e-08 31.5 18.6 3.3e-07 29.6 1.0 2.4 2 0 0 2 2 2 2 Transmembrane alpha-helix domain V-set PF07686.17 PVD21815.1 - 1e-07 32.1 5.1 0.0047 17.1 0.0 4.8 5 0 0 5 5 4 2 Immunoglobulin V-set domain AAA_19 PF13245.6 PVD21815.1 - 1.3e-06 28.8 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PVD21815.1 - 2e-06 27.7 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain I-set PF07679.16 PVD21815.1 - 2.1e-06 27.7 1.5 2.2 8.4 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin I-set domain AAA_16 PF13191.6 PVD21815.1 - 0.00016 22.1 0.0 0.66 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Ig_3 PF13927.6 PVD21815.1 - 0.00018 22.1 10.6 1.4 9.6 0.1 4.8 4 1 0 4 4 3 2 Immunoglobulin domain Syndecan PF01034.20 PVD21815.1 - 0.0014 18.5 6.8 0.059 13.3 2.0 2.6 2 0 0 2 2 2 2 Syndecan domain EVC2_like PF12297.8 PVD21815.1 - 0.0039 15.9 0.1 1.7 7.2 0.0 2.4 2 0 0 2 2 2 2 Ellis van Creveld protein 2 like protein IL6Ra-bind PF09240.10 PVD21815.1 - 0.0046 17.4 4.0 20 5.7 0.0 4.2 4 0 0 4 4 4 0 Interleukin-6 receptor alpha chain, binding Amnionless PF14828.6 PVD21815.1 - 0.006 15.5 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 1 Amnionless TERB2 PF15101.6 PVD21815.1 - 0.0077 16.3 0.4 5.5 7.0 0.1 3.4 3 0 0 3 3 3 1 Telomere-associated protein TERB2 DUF3377 PF11857.8 PVD21815.1 - 0.01 15.7 3.7 0.081 12.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 PVD21815.1 - 0.013 16.4 0.2 13 6.7 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TK PF00265.18 PVD21815.1 - 0.014 15.3 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Thymidine kinase LPG_synthase_TM PF03706.13 PVD21815.1 - 0.017 14.7 0.0 0.62 9.5 0.0 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF4808 PF16066.5 PVD21815.1 - 0.031 14.8 0.1 8.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Marek_A PF02124.15 PVD21815.1 - 0.046 13.6 0.9 45 3.8 0.1 3.4 3 0 0 3 3 3 0 Marek's disease glycoprotein A AAA_11 PF13086.6 PVD21815.1 - 0.047 13.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain KdpD PF02702.17 PVD21815.1 - 0.065 12.7 0.0 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain KTI12 PF08433.10 PVD21815.1 - 0.073 12.5 0.1 7.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DEAD PF00270.29 PVD21815.1 - 0.08 12.7 0.0 21 4.8 0.0 3.0 2 1 0 3 3 3 0 DEAD/DEAH box helicase DUF3827 PF12877.7 PVD21815.1 - 0.082 11.3 1.8 1.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF4448 PF14610.6 PVD21815.1 - 0.14 11.9 2.1 1 9.1 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF4448) AAA_18 PF13238.6 PVD21815.1 - 0.16 12.6 0.2 35 5.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 PVD21815.1 - 0.16 11.7 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Insulin_TMD PF17870.1 PVD21815.1 - 0.39 10.8 3.0 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment ig PF00047.25 PVD21815.1 - 3.4 7.9 11.0 1 9.6 0.7 4.3 4 0 0 4 4 4 0 Immunoglobulin domain AAA_22 PF13401.6 PVD21816.1 - 1e-18 67.9 0.0 2.3e-06 27.9 0.0 4.0 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.6 PVD21816.1 - 4.3e-15 56.3 0.0 0.0015 18.9 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_30 PF13604.6 PVD21816.1 - 1.2e-14 54.5 0.0 0.0019 17.9 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 PVD21816.1 - 3e-13 50.5 0.0 0.0051 17.2 0.0 3.6 3 0 0 3 3 3 3 AAA ATPase domain AAA PF00004.29 PVD21816.1 - 7.2e-10 39.4 0.0 0.076 13.4 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 PVD21816.1 - 1.5e-08 33.9 0.1 0.1 11.5 0.0 3.5 3 0 0 3 3 3 3 Methylmalonyl Co-A mutase-associated GTPase MeaB V-set PF07686.17 PVD21816.1 - 5e-08 33.1 15.3 0.0022 18.2 0.4 6.6 6 0 0 6 6 6 1 Immunoglobulin V-set domain Marek_A PF02124.15 PVD21816.1 - 6.6e-08 32.6 1.3 0.0031 17.4 0.5 3.8 3 0 0 3 3 3 1 Marek's disease glycoprotein A AAA_5 PF07728.14 PVD21816.1 - 3.2e-07 30.4 0.2 0.25 11.3 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Ig_3 PF13927.6 PVD21816.1 - 4.9e-07 30.3 16.8 0.0021 18.6 0.5 6.6 6 1 0 6 6 6 2 Immunoglobulin domain I-set PF07679.16 PVD21816.1 - 2.7e-06 27.4 0.1 0.22 11.6 0.0 4.4 5 0 0 5 5 4 2 Immunoglobulin I-set domain IstB_IS21 PF01695.17 PVD21816.1 - 2.7e-06 27.2 0.0 0.51 10.0 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 PVD21816.1 - 7.5e-06 26.5 3.5 1.1 9.9 0.0 4.7 5 0 0 5 5 3 2 AAA domain SRP54 PF00448.22 PVD21816.1 - 1.5e-05 24.7 0.0 1.9 8.1 0.0 3.4 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_7 PF12775.7 PVD21816.1 - 5.9e-05 22.7 0.0 0.74 9.3 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_28 PF13521.6 PVD21816.1 - 8e-05 22.9 0.5 3.3 7.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 PVD21816.1 - 8.4e-05 22.5 0.2 4.8 6.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 PVD21816.1 - 0.00019 21.4 0.2 0.76 9.7 0.0 4.1 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.6 PVD21816.1 - 0.00019 21.2 0.1 3.8 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain ig PF00047.25 PVD21816.1 - 0.0014 18.8 4.7 0.39 10.9 0.2 5.2 5 0 0 5 5 4 1 Immunoglobulin domain ABC_tran PF00005.27 PVD21816.1 - 0.0017 18.8 2.5 8.2 6.9 0.0 4.2 5 0 0 5 5 3 0 ABC transporter RNA_helicase PF00910.22 PVD21816.1 - 0.0024 18.2 0.1 10 6.6 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.12 PVD21816.1 - 0.004 16.4 0.0 13 5.0 0.0 3.5 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.6 PVD21816.1 - 0.006 16.7 1.9 10 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 PVD21816.1 - 0.018 14.5 0.0 22 4.4 0.0 4.0 4 0 0 4 4 4 0 Chromatin associated protein KTI12 Env-gp36 PF09590.10 PVD21816.1 - 0.03 12.8 0.9 0.07 11.6 0.9 1.5 1 0 0 1 1 1 0 Lentivirus surface glycoprotein EphA2_TM PF14575.6 PVD21816.1 - 0.031 15.1 0.2 0.1 13.5 0.2 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ig_4 PF16680.5 PVD21816.1 - 0.062 13.6 5.6 1.4 9.3 0.4 4.1 4 0 0 4 4 2 0 T-cell surface glycoprotein CD3 delta chain DUF2119 PF09892.9 PVD21816.1 - 0.063 12.7 0.1 6.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) KdpD PF02702.17 PVD21816.1 - 0.092 12.2 0.0 6 6.3 0.0 3.0 3 0 0 3 3 3 0 Osmosensitive K+ channel His kinase sensor domain DUF853 PF05872.12 PVD21816.1 - 0.14 10.7 0.0 15 4.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Ig_2 PF13895.6 PVD21816.1 - 0.21 12.0 24.3 0.91 9.9 0.6 7.2 7 2 0 7 7 6 0 Immunoglobulin domain V-set_2 PF15910.5 PVD21816.1 - 7 6.8 10.9 34 4.6 0.1 5.7 6 1 1 7 7 5 0 ICOS V-set domain V-set PF07686.17 PVD21817.1 - 2.3e-09 37.4 8.9 0.056 13.6 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD21817.1 - 4.5e-06 27.2 12.6 0.011 16.3 0.5 4.0 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD21817.1 - 2.7e-05 24.2 0.3 0.36 10.9 0.1 3.9 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_4 PF16680.5 PVD21817.1 - 0.014 15.7 1.7 0.53 10.6 0.2 3.6 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain HMMR_N PF15905.5 PVD21818.1 - 0.00039 20.0 4.6 0.0005 19.6 4.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal V-SNARE PF05008.15 PVD21818.1 - 0.033 14.5 2.3 0.08 13.3 2.3 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.12 PVD21818.1 - 0.037 14.5 0.2 0.077 13.5 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TBCA PF02970.16 PVD21818.1 - 0.074 13.4 2.6 0.091 13.1 1.1 2.0 1 1 0 1 1 1 0 Tubulin binding cofactor A L31 PF09784.9 PVD21818.1 - 0.16 12.4 0.4 0.81 10.1 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Fib_alpha PF08702.10 PVD21818.1 - 0.22 11.7 2.7 0.46 10.7 2.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 PVD21818.1 - 0.22 9.4 1.1 0.27 9.1 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paralemmin PF03285.15 PVD21818.1 - 0.28 10.7 2.9 0.39 10.2 2.9 1.1 1 0 0 1 1 1 0 Paralemmin SlyX PF04102.12 PVD21818.1 - 0.65 10.7 7.0 0.39 11.4 3.1 2.4 1 1 2 3 3 3 0 SlyX DUF4164 PF13747.6 PVD21818.1 - 6.8 7.0 10.7 8.1 6.8 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Presenilin PF01080.17 PVD21819.1 - 0.67 8.7 1.8 0.68 8.6 1.8 1.0 1 0 0 1 1 1 0 Presenilin Trypsin PF00089.26 PVD21821.1 - 8.9e-39 133.6 0.0 1.2e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin 7TM_GPCR_Srx PF10328.9 PVD21823.1 - 0.0015 18.3 0.3 0.0019 17.9 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD21823.1 - 0.061 12.6 4.6 0.047 13.0 2.9 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4231 PF14015.6 PVD21823.1 - 0.37 11.3 2.2 8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) RhoGEF PF00621.20 PVD21824.1 - 2.9e-14 53.7 0.1 4.9e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PDZ_6 PF17820.1 PVD21824.1 - 6.8e-13 48.2 0.3 2.1e-12 46.7 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PVD21824.1 - 3.9e-10 39.9 1.4 6.2e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD21824.1 - 7e-08 32.7 0.1 2.1e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 PVD21824.1 - 3.4e-05 24.3 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 PH domain Tricorn_PDZ PF14685.6 PVD21824.1 - 0.0031 17.5 0.4 0.041 13.8 0.1 2.4 2 0 0 2 2 2 1 Tricorn protease PDZ domain PH_16 PF17838.1 PVD21824.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.9 1 0 0 1 1 1 0 PH domain MAM PF00629.23 PVD21827.1 - 3.6e-18 66.0 0.0 9.6e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu 7TM_GPCR_Srw PF10324.9 PVD21828.1 - 2.8e-12 46.6 7.6 3.9e-12 46.1 7.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD21828.1 - 2.3e-06 27.5 2.2 2.3e-06 27.5 2.2 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD21828.1 - 0.0054 16.1 4.9 0.012 15.0 4.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sushi PF00084.20 PVD21829.1 - 6e-84 276.5 53.4 9.4e-14 51.8 0.5 10.5 9 1 1 10 10 10 10 Sushi repeat (SCR repeat) HRM PF02793.22 PVD21829.1 - 0.012 15.9 0.7 0.012 15.9 0.7 6.2 8 0 0 8 8 8 0 Hormone receptor domain CBFD_NFYB_HMF PF00808.23 PVD21833.1 - 6.8e-12 45.5 0.6 1.3e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PVD21833.1 - 2.6e-05 24.6 1.3 0.00019 21.8 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PVD21833.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4672 PF15716.5 PVD21833.1 - 0.017 14.8 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) MRP-S26 PF14943.6 PVD21833.1 - 0.032 14.1 6.2 0.044 13.7 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Prothymosin PF03247.14 PVD21833.1 - 0.12 12.9 18.3 0.2 12.1 18.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family CK_II_beta PF01214.18 PVD21834.1 - 6.5e-56 189.0 1.7 5e-47 160.1 2.1 2.1 1 1 1 2 2 2 2 Casein kinase II regulatory subunit RHH_1 PF01402.21 PVD21834.1 - 0.037 14.0 0.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DpnI PF06044.12 PVD21834.1 - 0.068 12.8 0.0 9.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Dam-replacing family zf-TFIIB PF13453.6 PVD21834.1 - 0.1 12.0 1.0 2.6 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_SprT PF17283.2 PVD21834.1 - 0.15 12.0 1.7 1 9.3 0.2 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cys_rich_KTR PF14205.6 PVD21834.1 - 2.2 8.1 4.6 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR PKHD_C PF18331.1 PVD21835.1 - 0.00041 20.3 0.9 0.0066 16.5 0.1 3.7 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain Fez1 PF06818.15 PVD21835.1 - 0.0089 16.5 26.5 0.0089 16.5 26.5 12.2 3 2 10 13 13 13 5 Fez1 MtrG PF04210.13 PVD21835.1 - 1.4 8.8 3.1 17 5.4 0.1 3.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Ribosomal_L5e PF17144.4 PVD21836.1 - 1.7e-89 298.0 0.4 3.1e-89 297.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 PVD21836.1 - 1.8e-31 108.9 0.8 4.6e-31 107.6 0.8 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region AAA_12 PF13087.6 PVD21837.1 - 1.8e-54 184.4 0.0 3.9e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD21837.1 - 1.4e-52 179.1 0.8 1.4e-52 179.1 0.8 3.8 2 2 0 2 2 1 1 AAA domain AAA_30 PF13604.6 PVD21837.1 - 1.4e-14 54.3 0.0 6.7e-13 48.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain R3H PF01424.22 PVD21837.1 - 6.8e-12 45.2 0.1 2.1e-11 43.6 0.1 1.9 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 PVD21837.1 - 6.7e-11 42.7 0.0 5.2e-10 39.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain zf-AN1 PF01428.16 PVD21837.1 - 3.1e-09 36.8 9.0 6e-09 35.9 9.0 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger ResIII PF04851.15 PVD21837.1 - 3.2e-06 27.3 0.0 7.3e-05 22.8 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 PVD21837.1 - 1.1e-05 25.3 3.2 0.36 10.5 0.1 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA PF00004.29 PVD21837.1 - 0.00031 21.2 0.3 0.0015 18.9 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD21837.1 - 0.00032 21.0 0.1 0.0014 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 PVD21837.1 - 0.00037 20.5 0.7 0.003 17.6 0.1 2.7 3 0 0 3 3 3 1 Flavivirus DEAD domain AAA_25 PF13481.6 PVD21837.1 - 0.00052 19.6 0.1 0.0031 17.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 PVD21837.1 - 0.00078 19.3 1.1 0.0054 16.5 1.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 PVD21837.1 - 0.00097 19.6 0.1 0.003 18.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 PVD21837.1 - 0.0018 18.2 0.0 0.15 11.9 0.0 3.4 3 0 0 3 3 3 1 Helicase PhoH PF02562.16 PVD21837.1 - 0.0019 17.7 0.0 0.021 14.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 PVD21837.1 - 0.0027 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 PVD21837.1 - 0.0039 17.1 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 PVD21837.1 - 0.023 14.2 0.0 0.023 14.2 0.0 2.8 2 2 0 2 2 1 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.27 PVD21837.1 - 0.032 14.7 3.9 0.091 13.3 0.0 3.1 2 1 0 2 2 2 0 ABC transporter PIF1 PF05970.14 PVD21837.1 - 0.039 13.1 0.0 0.45 9.6 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_33 PF13671.6 PVD21837.1 - 0.075 13.2 0.0 0.37 11.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 PVD21837.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Zot PF05707.12 PVD21837.1 - 0.088 12.4 0.2 0.95 9.1 0.0 2.4 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) Astacin PF01400.24 PVD21837.1 - 0.092 12.3 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 1 0 Astacin (Peptidase family M12A) NTPase_1 PF03266.15 PVD21837.1 - 0.11 12.4 2.5 1.2 9.1 2.5 2.4 1 1 0 1 1 1 0 NTPase DUF2075 PF09848.9 PVD21837.1 - 3 7.0 9.0 0.21 10.8 0.5 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF730 PF05325.11 PVD21838.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF730) YabA PF06156.13 PVD21838.1 - 0.3 11.8 3.4 1.3 9.7 3.4 2.1 1 0 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 PVD21838.1 - 1.4 9.4 14.2 0.078 13.5 7.9 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 PVD21838.1 - 2 8.9 9.9 7.8 7.0 9.9 2.0 1 0 0 1 1 1 0 Cell division protein ZapB DivIVA PF05103.13 PVD21838.1 - 9.6 6.3 10.1 40 4.3 10.1 2.1 1 0 0 1 1 1 0 DivIVA protein HAD_2 PF13419.6 PVD21839.1 - 6.3e-17 62.2 0.0 8.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD21839.1 - 3.5e-12 47.1 0.0 4.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD21839.1 - 3.6e-06 27.0 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LRR_9 PF14580.6 PVD21840.1 - 5.5e-16 58.5 5.9 2.5e-15 56.4 2.8 3.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 PVD21840.1 - 3.8e-12 46.2 11.0 3.5e-05 24.1 1.2 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD21840.1 - 6.1e-10 38.7 12.1 9.8e-05 22.0 0.4 3.3 2 1 0 2 2 2 2 Leucine rich repeat LZ3wCH PF18517.1 PVD21840.1 - 0.13 12.4 0.9 0.61 10.2 0.1 2.8 2 0 0 2 2 2 0 Leucine zipper with capping helix domain LRR_1 PF00560.33 PVD21840.1 - 0.28 11.9 10.1 27 5.8 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat DUF917 PF06032.12 PVD21841.1 - 3.1e-102 342.0 0.1 5.8e-101 337.8 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 PVD21841.1 - 2.2e-33 115.4 1.4 6.8e-31 107.3 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 PVD21841.1 - 6e-32 111.1 1.6 7.7e-27 94.3 0.2 3.7 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase FtsA PF14450.6 PVD21841.1 - 4.7e-05 23.7 4.7 0.29 11.6 0.0 3.7 3 2 0 3 3 3 2 Cell division protein FtsA MutL PF13941.6 PVD21841.1 - 4.9e-05 22.1 4.6 0.019 13.6 1.0 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 PVD21841.1 - 0.0002 21.0 0.0 0.19 11.2 1.3 2.7 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family RNase_PH PF01138.21 PVD21842.1 - 1.5e-25 90.2 0.0 2.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PVD21842.1 - 0.045 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 adh_short_C2 PF13561.6 PVD21843.1 - 3.9e-56 190.2 0.0 4.7e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD21843.1 - 1.5e-44 151.9 0.0 1.9e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD21843.1 - 2.9e-14 53.4 0.0 4.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD21843.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PVD21843.1 - 0.029 13.6 0.0 0.051 12.7 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein Ion_trans PF00520.31 PVD21847.1 - 1.9e-14 53.5 19.7 3.6e-14 52.6 19.4 1.6 1 1 0 1 1 1 1 Ion transport protein Ank PF00023.30 PVD21847.1 - 1.8e-11 43.9 0.0 0.0013 19.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 PVD21847.1 - 2e-11 44.3 0.0 0.00024 21.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD21847.1 - 4.2e-11 42.1 0.1 1.4e-05 25.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PVD21847.1 - 2.3e-09 37.6 0.1 0.0014 19.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 PVD21847.1 - 4.8e-09 35.4 10.4 4.8e-09 35.4 10.4 2.2 2 1 1 3 3 3 1 Polycystin cation channel Ank_5 PF13857.6 PVD21847.1 - 1.5e-07 31.6 0.1 0.0091 16.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3836 PF12930.7 PVD21847.1 - 0.33 10.7 4.7 0.91 9.3 3.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF3836) DUF2157 PF09925.9 PVD21847.1 - 0.48 10.2 5.6 1.6 8.5 1.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) TSP_NTD PF17804.1 PVD21847.1 - 9.6 6.4 7.7 4.2 7.6 1.6 2.2 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Glyco_hydro_31 PF01055.26 PVD21848.1 - 1.4e-32 113.5 0.0 1.6e-30 106.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 31 DUF2475 PF10629.9 PVD21849.1 - 4.9e-27 93.9 13.8 1.5e-07 31.5 0.3 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2475) DUF725 PF05267.12 PVD21849.1 - 0.052 13.5 0.9 6.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF725) HTH_16 PF12645.7 PVD21849.1 - 0.095 12.8 0.2 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain VWA PF00092.28 PVD21850.1 - 2.2e-52 177.8 3.0 3.7e-27 95.7 0.5 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD21850.1 - 6.4e-27 94.3 1.1 6.7e-14 52.4 0.3 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain CBM_14 PF01607.24 PVD21850.1 - 1.6e-12 47.3 2.3 0.00029 20.9 0.0 3.5 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain VWA_3 PF13768.6 PVD21850.1 - 7.8e-07 29.2 0.7 0.011 15.7 0.1 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Copine PF07002.16 PVD21850.1 - 0.18 11.2 0.9 0.29 10.5 0.2 1.7 2 0 0 2 2 2 0 Copine MGC-24 PF05283.11 PVD21850.1 - 0.33 11.4 12.5 1.3 9.5 12.5 2.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_47 PF01532.20 PVD21851.1 - 2e-107 360.0 0.0 3.7e-107 359.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 PVD21851.1 - 3.6e-09 36.5 0.0 7.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PA domain DSPc PF00782.20 PVD21853.1 - 2.5e-26 92.1 0.0 3.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD21853.1 - 0.00021 21.0 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PVD21853.1 - 0.0072 16.6 0.1 0.017 15.4 0.1 1.6 1 1 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 PVD21853.1 - 0.024 14.8 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Integrase_H2C2 PF17921.1 PVD21854.1 - 1.4e-05 25.1 1.8 2.8e-05 24.1 1.8 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_8 PF13855.6 PVD21856.1 - 2.7e-91 299.3 114.3 4e-14 52.1 8.9 13.1 7 2 5 13 13 13 12 Leucine rich repeat LRR_4 PF12799.7 PVD21856.1 - 3.1e-54 180.0 106.0 8.5e-07 29.2 0.8 15.6 10 3 6 17 17 17 17 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD21856.1 - 3.6e-19 69.0 0.0 0.0031 17.5 0.0 6.9 5 2 1 7 7 7 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD21856.1 - 2.2e-16 57.9 108.9 0.0033 17.8 1.7 24.4 26 2 1 27 27 27 9 Leucine Rich Repeat LRR_9 PF14580.6 PVD21856.1 - 9.1e-16 57.8 37.9 0.0084 15.6 0.6 7.4 3 1 3 7 7 7 7 Leucine-rich repeat LRR_6 PF13516.6 PVD21856.1 - 8.4e-06 25.4 104.6 0.56 10.4 1.0 22.3 23 0 0 23 23 23 5 Leucine Rich repeat Pou PF00157.17 PVD21856.1 - 0.014 15.4 1.0 5.3 7.1 0.1 3.8 2 1 1 3 3 3 0 Pou domain - N-terminal to homeobox domain SCAI PF12070.8 PVD21857.1 - 2.6e-231 769.1 0.1 3.1e-231 768.9 0.1 1.0 1 0 0 1 1 1 1 Protein SCAI Apolipoprotein PF01442.18 PVD21858.1 - 5.2e-06 26.5 7.7 1.4e-05 25.1 7.7 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD21858.1 - 9.3e-05 22.5 2.4 0.12 12.4 0.2 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 PVD21858.1 - 0.0014 18.0 0.9 0.3 10.4 0.1 2.1 2 0 0 2 2 2 2 SF-assemblin/beta giardin ApoO PF09769.9 PVD21858.1 - 0.0097 15.9 0.6 0.66 9.9 0.1 2.3 2 0 0 2 2 2 1 Apolipoprotein O DUF1640 PF07798.11 PVD21858.1 - 0.039 14.0 0.3 4.9 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF883 PF05957.13 PVD21858.1 - 0.07 13.7 5.2 2.2 8.9 0.2 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 PVD21858.1 - 0.2 11.0 3.5 1.3 8.3 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PVD21858.1 - 0.22 11.6 5.6 1.3 9.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 PVD21858.1 - 0.32 10.8 3.9 1.2 8.9 1.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HIP1_clath_bdg PF16515.5 PVD21858.1 - 0.32 11.6 7.7 5.1 7.8 0.7 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fzo_mitofusin PF04799.13 PVD21858.1 - 0.36 10.4 2.2 1.1 8.8 0.2 2.4 2 1 0 2 2 2 0 fzo-like conserved region MukF_M PF17192.4 PVD21858.1 - 0.47 10.2 2.3 8.6 6.1 0.2 2.6 2 1 0 2 2 2 0 MukF middle domain ApoLp-III PF07464.11 PVD21858.1 - 0.8 9.8 8.2 1 9.5 0.8 2.5 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 PVD21859.1 - 2.3e-06 27.6 17.8 1.9e-05 24.7 16.9 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD21859.1 - 0.00022 21.3 5.0 0.038 14.0 2.5 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Gp58 PF07902.11 PVD21859.1 - 0.00065 18.1 3.9 0.00079 17.8 3.9 1.1 1 0 0 1 1 1 1 gp58-like protein DUF1640 PF07798.11 PVD21859.1 - 0.0015 18.6 5.6 0.0033 17.5 4.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) Filament PF00038.21 PVD21859.1 - 0.0016 18.1 6.4 0.003 17.2 6.4 1.4 1 1 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 PVD21859.1 - 0.0053 16.3 3.7 0.0053 16.3 3.7 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF1351 PF07083.11 PVD21859.1 - 0.007 16.2 0.1 0.059 13.1 0.0 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1351) OmpH PF03938.14 PVD21859.1 - 0.011 16.1 3.7 0.034 14.5 3.7 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 PVD21859.1 - 0.012 15.9 3.5 0.12 12.7 0.3 3.4 2 1 3 5 5 5 0 Tup N-terminal MPS2 PF17060.5 PVD21859.1 - 0.016 14.5 1.8 0.018 14.4 1.1 1.4 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF1664 PF07889.12 PVD21859.1 - 0.016 15.2 5.4 0.028 14.4 1.5 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 PVD21859.1 - 0.036 13.4 10.7 0.045 13.1 8.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 PVD21859.1 - 0.099 13.3 12.5 0.15 12.7 3.3 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SKA2 PF16740.5 PVD21859.1 - 0.1 12.4 3.4 0.22 11.3 2.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF883 PF05957.13 PVD21859.1 - 0.11 13.1 18.1 0.72 10.5 2.3 3.7 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF1690 PF07956.11 PVD21859.1 - 0.14 12.6 10.7 0.078 13.4 3.7 2.5 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) ApoO PF09769.9 PVD21859.1 - 0.18 11.8 4.7 8.8 6.3 0.1 3.3 1 1 2 3 3 3 0 Apolipoprotein O GCN5L1 PF06320.13 PVD21859.1 - 0.2 11.8 3.8 9.1 6.5 0.0 2.4 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Prominin PF05478.11 PVD21859.1 - 0.22 9.4 3.8 0.25 9.2 3.3 1.4 1 1 0 1 1 1 0 Prominin KxDL PF10241.9 PVD21859.1 - 0.26 11.6 6.6 2.1 8.7 0.3 2.9 2 1 2 4 4 3 0 Uncharacterized conserved protein COG2 PF06148.11 PVD21859.1 - 0.37 10.9 8.0 2.4 8.3 2.6 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V-SNARE PF05008.15 PVD21859.1 - 0.37 11.2 6.3 2.9 8.3 0.5 3.9 1 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.11 PVD21859.1 - 0.47 11.0 7.8 51 4.5 7.8 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal LMP PF04778.12 PVD21859.1 - 0.48 10.3 4.1 1.2 9.0 0.6 2.6 1 1 2 3 3 3 0 LMP repeated region Spc7 PF08317.11 PVD21859.1 - 0.56 9.0 8.1 0.49 9.2 6.3 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein IFP_35_N PF07334.13 PVD21859.1 - 0.58 10.3 3.6 0.95 9.6 0.5 2.8 3 1 1 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Prefoldin_2 PF01920.20 PVD21859.1 - 0.59 10.1 3.7 19 5.2 0.1 3.2 2 1 2 4 4 3 0 Prefoldin subunit HBS1_N PF08938.10 PVD21859.1 - 0.9 9.9 3.0 4.9 7.5 1.8 2.7 1 1 1 2 2 2 0 HBS1 N-terminus K-box PF01486.17 PVD21859.1 - 0.94 9.7 7.2 2.2 8.5 0.4 3.6 1 1 2 3 3 3 0 K-box region YlqD PF11068.8 PVD21859.1 - 1.2 9.6 4.4 1.7 9.0 1.7 2.2 1 1 2 3 3 3 0 YlqD protein HAUS-augmin3 PF14932.6 PVD21859.1 - 1.3 8.5 10.5 0.54 9.8 6.7 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 M PF02370.16 PVD21859.1 - 1.4 9.8 0.1 1.4 9.8 0.1 4.6 5 1 1 6 6 3 0 M protein repeat Metal_resist PF13801.6 PVD21859.1 - 1.7 8.8 11.7 0.6 10.3 7.0 2.3 1 1 0 2 2 2 0 Heavy-metal resistance DUF4404 PF14357.6 PVD21859.1 - 5.2 7.8 12.7 62 4.3 0.3 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4404) zf-H2C2_2 PF13465.6 PVD21862.1 - 5.6e-10 39.2 14.2 1.9e-05 24.9 2.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21862.1 - 6.1e-10 39.0 14.6 9.8e-05 22.6 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD21862.1 - 2.4e-08 34.1 12.4 0.00079 20.1 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 PVD21862.1 - 2.1e-05 24.7 5.4 0.0093 16.2 0.1 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 PVD21862.1 - 0.0038 17.3 5.2 0.21 11.8 1.0 2.4 2 0 0 2 2 2 1 AN1-like Zinc finger zf-C2H2_6 PF13912.6 PVD21862.1 - 0.0085 16.1 10.8 0.37 10.8 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 PVD21862.1 - 0.0097 15.5 1.3 1.9 8.1 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 PVD21862.1 - 0.013 15.8 4.1 0.66 10.3 3.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 PVD21862.1 - 0.013 15.6 4.7 0.064 13.4 4.7 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.7 PVD21862.1 - 0.015 15.7 6.6 4 8.0 5.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GAGA PF09237.11 PVD21862.1 - 0.024 14.4 4.0 0.94 9.3 1.0 2.3 1 1 1 2 2 2 0 GAGA factor zf-H2C2_5 PF13909.6 PVD21862.1 - 0.035 13.8 14.7 0.29 10.9 7.9 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Sprouty PF05210.13 PVD21862.1 - 0.052 13.9 0.7 0.081 13.3 0.7 1.4 1 0 0 1 1 1 0 Sprouty protein (Spry) TRAF6_Z2 PF18048.1 PVD21862.1 - 0.065 13.3 0.1 0.065 13.3 0.1 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HE PF16278.5 PVD21862.1 - 0.075 13.5 6.5 3.2 8.3 1.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 PVD21862.1 - 0.086 12.6 6.4 1 9.2 0.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-FPG_IleRS PF06827.14 PVD21862.1 - 0.091 12.6 3.7 0.28 11.1 0.8 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-BED PF02892.15 PVD21862.1 - 0.093 12.8 5.4 0.16 12.0 2.0 2.2 2 0 0 2 2 2 0 BED zinc finger DUF2072 PF09845.9 PVD21862.1 - 0.15 12.4 3.8 0.4 11.0 3.8 1.9 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-LYAR PF08790.11 PVD21862.1 - 0.15 12.0 3.6 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 PVD21862.1 - 0.22 11.4 7.1 2.2 8.2 0.9 2.6 3 0 0 3 3 3 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 PVD21862.1 - 0.27 11.9 4.8 0.39 11.4 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_primase_lrg PF04104.14 PVD21862.1 - 0.35 10.2 2.4 0.59 9.5 2.2 1.4 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit CpXC PF14353.6 PVD21862.1 - 0.48 10.5 3.6 23 5.1 3.7 2.3 1 1 0 1 1 1 0 CpXC protein zinc_ribbon_9 PF14369.6 PVD21862.1 - 0.53 10.6 4.7 23 5.4 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon DUF629 PF04780.12 PVD21862.1 - 0.61 8.6 4.6 2.4 6.6 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-HIT PF04438.16 PVD21862.1 - 0.86 9.5 5.5 9.6 6.2 0.4 2.3 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_4 PF13717.6 PVD21862.1 - 3.3 7.7 6.1 22 5.1 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 PVD21863.1 - 2.2e-20 72.1 23.2 3.5e-07 30.4 0.7 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD21863.1 - 4.8e-17 61.4 40.8 2.9e-06 27.4 1.3 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD21863.1 - 1.2e-13 50.9 5.6 0.0026 18.0 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD21863.1 - 4.8e-07 30.1 17.4 6.5e-05 23.4 1.2 5.9 5 1 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD21863.1 - 2.2e-06 27.5 23.6 0.021 14.9 0.7 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-ribbon_3 PF13248.6 PVD21863.1 - 0.00097 18.5 1.7 0.82 9.2 0.1 2.6 2 0 0 2 2 2 2 zinc-ribbon domain zf_C2H2_ZHX PF18387.1 PVD21863.1 - 0.0031 17.1 9.3 0.15 11.7 2.8 3.4 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 PVD21863.1 - 0.0043 17.1 7.9 0.0063 16.6 0.5 3.1 1 1 2 3 3 3 2 Zinc ribbon domain zf-Di19 PF05605.12 PVD21863.1 - 0.0049 17.1 14.1 0.011 16.0 5.5 3.7 3 1 1 4 4 3 3 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 PVD21863.1 - 0.0069 16.4 4.5 0.075 13.0 2.2 2.3 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 PVD21863.1 - 0.013 15.9 14.7 0.44 11.0 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.7 PVD21863.1 - 0.022 14.8 7.1 0.78 9.8 7.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon TRAF6_Z2 PF18048.1 PVD21863.1 - 0.025 14.7 3.0 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-RING_7 PF02591.15 PVD21863.1 - 0.044 14.0 0.6 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain Cys_rich_CPXG PF14255.6 PVD21863.1 - 0.066 13.1 2.6 0.92 9.5 0.1 3.1 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-C2H2_9 PF16293.5 PVD21863.1 - 0.067 13.0 8.4 0.57 10.1 0.1 3.5 2 1 2 4 4 3 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 PVD21863.1 - 0.11 12.4 15.0 5 7.1 0.7 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-CHCC PF10276.9 PVD21863.1 - 0.18 11.9 0.3 0.18 11.9 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger domain TerY_C PF15616.6 PVD21863.1 - 0.18 11.9 0.9 0.33 11.1 0.6 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-CCHC_5 PF14787.6 PVD21863.1 - 0.19 11.5 6.6 1 9.1 1.2 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zinc_ribbon_15 PF17032.5 PVD21863.1 - 0.21 12.4 5.9 0.59 10.9 2.7 2.5 1 1 2 3 3 3 0 zinc-ribbon family FYDLN_acid PF09538.10 PVD21863.1 - 0.22 12.2 3.7 14 6.4 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.6 PVD21863.1 - 0.22 11.3 5.4 3.7 7.4 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 PVD21863.1 - 0.22 11.6 7.2 2.3 8.3 0.8 3.5 2 1 1 3 3 3 0 CpXC protein zf-C2HC_2 PF13913.6 PVD21863.1 - 0.27 11.2 20.2 0.42 10.6 1.4 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.7 PVD21863.1 - 0.3 11.1 13.9 19 5.4 6.3 4.1 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Thioredoxin_4 PF13462.6 PVD21863.1 - 0.33 11.1 4.3 0.86 9.7 0.1 3.0 4 0 0 4 4 3 0 Thioredoxin EGF_CA PF07645.15 PVD21863.1 - 0.51 10.6 3.8 1.7 8.9 0.1 2.9 3 0 0 3 3 3 0 Calcium-binding EGF domain LIM PF00412.22 PVD21863.1 - 0.51 10.6 9.2 27 5.1 6.3 3.5 2 1 0 2 2 2 0 LIM domain Prok-RING_1 PF14446.6 PVD21863.1 - 0.76 9.7 10.1 4.1 7.4 0.1 4.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 SelP_N PF04592.14 PVD21863.1 - 0.87 8.9 10.2 1.9 7.9 10.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ogr_Delta PF04606.12 PVD21863.1 - 0.92 9.5 7.1 10 6.2 0.2 3.4 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 PVD21863.1 - 1.1 9.8 17.1 1.5 9.3 0.8 4.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1610 PF07754.11 PVD21863.1 - 2.2 8.3 8.1 3.1 7.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Elf1 PF05129.13 PVD21863.1 - 2.3 8.4 9.8 4.1 7.5 1.9 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like PyrI_C PF02748.15 PVD21863.1 - 2.4 8.1 5.9 8 6.5 0.0 3.2 2 1 2 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_9 PF14369.6 PVD21863.1 - 2.5 8.4 11.2 4 7.8 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon HNH_5 PF14279.6 PVD21863.1 - 3.1 7.7 8.5 16 5.4 0.8 3.5 3 1 0 3 3 3 0 HNH endonuclease zinc-ribbons_6 PF07191.12 PVD21863.1 - 3.4 7.7 8.6 5e+02 0.8 8.6 3.5 1 1 0 1 1 1 0 zinc-ribbons GFA PF04828.14 PVD21863.1 - 4.3 7.7 7.9 44 4.5 4.5 2.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 PVD21863.1 - 4.7 7.0 7.5 2.1 8.2 0.4 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Filamin PF00630.19 PVD21864.1 - 0.041 14.7 0.1 0.089 13.6 0.1 1.4 1 1 0 1 1 1 0 Filamin/ABP280 repeat Cas9-BH PF16593.5 PVD21865.1 - 0.0046 16.6 5.6 0.016 14.9 5.6 2.0 1 0 0 1 1 1 1 Bridge helix of CRISPR-associated endonuclease Cas9 Adap_comp_sub PF00928.21 PVD21866.1 - 6.2e-50 170.0 0.0 8.2e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PVD21866.1 - 0.00019 21.4 0.2 0.00037 20.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Filament PF00038.21 PVD21867.1 - 0.0027 17.3 9.1 0.0027 17.3 9.1 5.8 1 1 3 5 5 5 2 Intermediate filament protein ATG16 PF08614.11 PVD21867.1 - 0.013 15.8 18.3 0.013 15.8 18.3 7.9 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 PVD21867.1 - 0.018 15.3 5.8 0.018 15.3 5.8 7.7 2 2 5 8 8 8 0 Tubulin binding cofactor A DUF4362 PF14275.6 PVD21867.1 - 0.049 13.9 0.1 0.26 11.6 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4362) Pox_A_type_inc PF04508.12 PVD21867.1 - 0.082 12.8 0.0 0.082 12.8 0.0 6.1 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 PVD21867.1 - 0.094 12.9 0.2 0.094 12.9 0.2 7.9 2 2 7 9 9 9 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 PVD21867.1 - 0.22 10.9 110.0 0.042 13.3 26.6 5.1 1 1 4 5 5 5 0 Golgin subfamily A member 5 Fez1 PF06818.15 PVD21867.1 - 3 8.2 101.0 0.4 11.1 21.1 6.3 1 1 4 5 5 5 0 Fez1 Acyl-CoA_dh_1 PF00441.24 PVD21868.1 - 2.1e-47 161.1 3.6 3e-47 160.6 3.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD21868.1 - 4.5e-29 101.4 0.1 9e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD21868.1 - 3.4e-26 91.3 0.0 7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD21868.1 - 1.7e-18 67.2 2.5 2.7e-18 66.5 2.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 PVD21868.1 - 0.00087 19.0 0.2 0.0071 16.0 0.2 2.4 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal WAP PF00095.21 PVD21869.1 - 1.3e-06 28.6 14.2 2.5e-06 27.7 14.2 1.5 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' TPR_12 PF13424.6 PVD21870.1 - 1.5e-25 89.3 10.3 3.7e-10 40.0 0.4 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD21870.1 - 2.6e-09 36.5 9.7 0.11 12.6 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD21870.1 - 7.4e-07 28.8 14.6 0.13 12.2 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD21870.1 - 4.3e-06 26.3 4.3 0.17 11.8 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD21870.1 - 0.0056 16.1 1.5 0.0056 16.1 1.5 2.9 2 1 1 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 PVD21870.1 - 0.0063 16.5 11.9 0.27 11.4 0.2 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD21870.1 - 0.091 13.0 1.1 2 8.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 PVD21870.1 - 0.11 11.9 0.0 0.94 8.8 0.0 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 PVD21870.1 - 0.28 12.1 11.0 12 7.0 0.1 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat C2 PF00168.30 PVD21873.1 - 2.2e-44 149.9 0.2 6.3e-24 84.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD21873.1 - 0.0049 16.4 0.0 0.093 12.3 0.0 2.2 2 0 0 2 2 2 1 CEP76 C2 domain DUF1315 PF07023.12 PVD21873.1 - 0.013 15.6 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1315) DOCK-C2 PF14429.6 PVD21873.1 - 0.033 14.0 0.4 1.6 8.5 0.1 2.2 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Stevor PF17410.2 PVD21874.1 - 0.15 11.6 1.8 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame FAM176 PF14851.6 PVD21874.1 - 0.24 11.1 2.3 0.31 10.7 1.1 1.8 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 PVD21874.1 - 1.6 9.2 6.3 2.6 8.5 6.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 PVD21874.1 - 4 5.6 4.6 5.8 5.1 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 PVD21876.1 - 0.054 13.8 30.2 0.073 13.4 30.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AF-4 PF05110.13 PVD21876.1 - 1.1 7.3 33.3 1.1 7.3 33.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 PVD21876.1 - 1.7 7.3 19.9 1.9 7.2 19.9 1.2 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 PVD21878.1 - 3.5e-134 448.8 1.2 6.3e-134 447.9 1.2 1.3 1 1 0 1 1 1 1 Mitoguardin ATF7IP_BD PF16788.5 PVD21878.1 - 0.098 12.7 0.7 0.17 12.0 0.7 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain PrkA PF06798.12 PVD21882.1 - 0.0031 17.2 2.5 0.0067 16.1 2.5 1.6 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain DUF3811 PF11656.8 PVD21882.1 - 0.0052 17.1 2.6 0.0052 17.1 2.6 2.9 4 0 0 4 4 4 1 YjbD family (DUF3811) DUF5447 PF17525.2 PVD21882.1 - 0.053 14.0 0.3 0.13 12.7 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5447) SPATIAL PF15256.6 PVD21883.1 - 0.097 13.0 0.3 0.14 12.5 0.3 1.2 1 0 0 1 1 1 0 SPATIAL CxC2 PF18803.1 PVD21884.1 - 1.6e-07 31.4 0.1 1.6e-07 31.4 0.1 3.0 4 0 0 4 4 4 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 PVD21884.1 - 9.2e-07 29.0 0.1 9.2e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases DUF4802 PF16060.5 PVD21884.1 - 6.3 7.0 7.2 12 6.1 6.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4802) zf-RING_2 PF13639.6 PVD21885.1 - 8.4e-09 35.6 2.8 8.4e-09 35.6 2.8 4.7 3 2 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 PVD21885.1 - 4.4e-08 32.7 6.1 4.4e-08 32.7 6.1 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD21885.1 - 1.9e-06 27.6 2.0 1.9e-06 27.6 2.0 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21885.1 - 6.9e-06 25.8 0.5 6.9e-06 25.8 0.5 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD21885.1 - 0.00018 21.5 2.4 0.00066 19.7 2.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD21885.1 - 0.00042 20.6 3.7 0.00042 20.6 3.7 3.8 2 2 1 3 3 3 1 RING-H2 zinc finger domain Trypan_PARP PF05887.11 PVD21885.1 - 3.6 7.6 7.0 4.2 7.4 0.6 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) LTD PF00932.19 PVD21888.1 - 1.3e-10 41.6 0.2 2.4e-10 40.7 0.2 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Filament PF00038.21 PVD21888.1 - 3.3e-10 40.0 36.7 6e-10 39.2 36.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein 2_5_RNA_ligase2 PF13563.6 PVD21888.1 - 0.16 11.8 2.9 0.36 10.7 0.3 2.5 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily HOOK PF05622.12 PVD21888.1 - 0.93 7.6 43.5 0.12 10.6 17.7 2.2 1 1 1 2 2 2 0 HOOK protein MAD PF05557.13 PVD21888.1 - 3 6.1 44.9 0.082 11.3 29.8 2.4 1 1 0 2 2 2 0 Mitotic checkpoint protein FlaC_arch PF05377.11 PVD21888.1 - 5.4 7.5 31.5 0.25 11.8 0.6 5.9 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) Filament PF00038.21 PVD21889.1 - 2.9e-28 99.4 43.3 2.5e-16 60.2 29.6 2.3 1 1 1 2 2 2 2 Intermediate filament protein LTD PF00932.19 PVD21889.1 - 2.7e-09 37.3 0.1 5.3e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Spc7 PF08317.11 PVD21889.1 - 0.0017 17.3 36.6 0.13 11.2 16.0 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Adeno_E1B_19K PF01691.16 PVD21889.1 - 0.043 13.4 0.3 0.088 12.3 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Phage_HK97_TLTM PF06120.11 PVD21889.1 - 0.056 12.6 15.0 0.047 12.9 2.3 2.2 2 0 0 2 2 2 0 Tail length tape measure protein TMF_TATA_bd PF12325.8 PVD21889.1 - 0.12 12.6 34.7 0.059 13.6 13.0 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Methyltr_RsmF_N PF17125.5 PVD21889.1 - 0.15 12.6 0.6 0.47 11.0 0.6 1.9 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF GTP-bdg_M PF16360.5 PVD21889.1 - 0.25 12.0 15.2 0.57 10.8 0.3 4.3 1 1 4 5 5 5 0 GTP-binding GTPase Middle Region DUF3584 PF12128.8 PVD21889.1 - 0.35 8.3 34.0 0.52 7.7 34.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TolA_bind_tri PF16331.5 PVD21889.1 - 0.9 9.7 34.8 2.1 8.5 1.9 4.5 1 1 3 4 4 4 0 TolA binding protein trimerisation HIP1_clath_bdg PF16515.5 PVD21889.1 - 1.3 9.7 40.3 0.43 11.2 10.4 3.7 1 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPP PF04728.13 PVD21889.1 - 1.7 9.1 11.8 4.8 7.6 3.5 3.5 3 1 0 3 3 3 0 Lipoprotein leucine-zipper APG6_N PF17675.1 PVD21889.1 - 2.4 8.7 48.3 0.034 14.7 12.8 3.4 1 1 1 3 3 3 0 Apg6 coiled-coil region FlaC_arch PF05377.11 PVD21889.1 - 2.6 8.5 16.5 0.74 10.3 1.5 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) FAM184 PF15665.5 PVD21889.1 - 2.7 7.7 35.2 0.24 11.2 19.0 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF3450 PF11932.8 PVD21889.1 - 3.1 7.1 30.8 4.7 6.4 15.4 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4988 PF16378.5 PVD21889.1 - 3.1 7.4 7.5 0.81 9.3 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function USP8_interact PF08941.10 PVD21889.1 - 4 7.2 13.0 8.5 6.1 3.2 2.5 2 0 0 2 2 2 0 USP8 interacting DUF948 PF06103.11 PVD21889.1 - 5.5 7.3 7.5 18 5.6 2.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4618 PF15397.6 PVD21889.1 - 6.6 6.1 32.4 0.55 9.6 3.3 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Filament PF00038.21 PVD21890.1 - 3.9e-23 82.5 8.9 4.6e-23 82.3 8.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 PVD21890.1 - 0.0022 18.0 2.8 0.0032 17.5 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD21890.1 - 0.0024 17.8 8.9 0.021 14.7 5.3 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain MbeD_MobD PF04899.12 PVD21890.1 - 0.0042 17.2 2.8 0.011 15.9 1.0 2.1 1 1 1 2 2 2 1 MbeD/MobD like Seryl_tRNA_N PF02403.22 PVD21890.1 - 0.0047 17.2 7.8 0.0068 16.6 7.8 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 PVD21890.1 - 0.0071 16.2 10.7 0.0094 15.8 10.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 PVD21890.1 - 0.017 14.0 7.1 0.022 13.7 7.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PVD21890.1 - 0.038 14.1 8.7 0.052 13.6 6.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 PVD21890.1 - 0.069 13.3 11.1 1.6 8.9 1.6 2.9 1 1 1 2 2 2 0 bZIP transcription factor ADIP PF11559.8 PVD21890.1 - 0.078 13.1 7.9 0.5 10.5 1.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding T7SS_ESX_EspC PF10824.8 PVD21890.1 - 0.11 12.9 0.6 5.8 7.5 0.0 2.6 2 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm BLOC1_2 PF10046.9 PVD21890.1 - 0.16 12.3 4.7 0.27 11.6 3.6 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 PVD21890.1 - 0.38 10.7 8.2 4.5 7.3 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit KELK PF15796.5 PVD21890.1 - 0.46 11.0 9.6 1.6 9.2 6.2 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4446 PF14584.6 PVD21890.1 - 0.47 10.4 5.0 0.32 11.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) YabA PF06156.13 PVD21890.1 - 0.5 11.0 6.4 6.9 7.4 6.2 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Tropomyosin PF00261.20 PVD21890.1 - 0.56 9.5 12.6 0.86 8.9 3.4 2.1 1 1 1 2 2 2 0 Tropomyosin TMPIT PF07851.13 PVD21890.1 - 0.83 8.8 4.5 1.1 8.5 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 PVD21890.1 - 1.1 9.8 11.4 0.99 9.9 1.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 PVD21890.1 - 4.4 8.0 7.6 13 6.5 0.3 2.2 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 PVD21890.1 - 6.7 6.9 16.8 0.73 10.0 4.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Filament PF00038.21 PVD21891.1 - 6.1e-22 78.6 6.2 8.3e-22 78.2 6.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein Apolipoprotein PF01442.18 PVD21891.1 - 0.00032 20.6 1.7 0.00055 19.9 1.7 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 PVD21891.1 - 0.003 17.6 1.8 0.0047 17.0 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MbeD_MobD PF04899.12 PVD21891.1 - 0.024 14.8 0.8 0.063 13.4 0.4 1.9 1 1 1 2 2 2 0 MbeD/MobD like KASH_CCD PF14662.6 PVD21891.1 - 0.057 13.3 6.4 0.12 12.2 6.4 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 PVD21891.1 - 0.14 12.1 5.0 1.9 8.5 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF4600 PF15372.6 PVD21891.1 - 0.14 12.6 3.2 0.63 10.5 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) bZIP_2 PF07716.15 PVD21891.1 - 0.19 11.8 10.9 0.14 12.2 4.8 2.6 2 1 0 2 2 2 0 Basic region leucine zipper BLOC1_2 PF10046.9 PVD21891.1 - 0.34 11.2 2.2 0.7 10.2 1.5 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 PVD21891.1 - 0.35 10.9 7.4 0.095 12.8 3.7 2.0 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 PVD21891.1 - 0.4 10.9 6.2 0.64 10.3 6.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1640 PF07798.11 PVD21891.1 - 0.44 10.6 5.5 4.2 7.4 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Tmemb_cc2 PF10267.9 PVD21891.1 - 0.52 9.4 7.1 1.8 7.7 7.0 2.0 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HALZ PF02183.18 PVD21891.1 - 0.65 10.3 3.6 3 8.1 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper KELK PF15796.5 PVD21891.1 - 0.86 10.1 8.4 0.22 12.0 3.6 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 PVD21891.1 - 0.86 9.6 7.4 2.8 7.9 7.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.6 PVD21891.1 - 1.4 8.9 3.4 2.2 8.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) APG6_N PF17675.1 PVD21891.1 - 1.9 9.0 6.1 4.9 7.7 6.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 PVD21891.1 - 4.6 7.1 6.4 7.9 6.3 0.5 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 PVD21891.1 - 4.7 7.4 7.4 4.6 7.4 3.0 2.7 2 1 0 2 2 2 0 bZIP transcription factor Arm PF00514.23 PVD21892.1 - 5.2e-09 35.8 0.2 1.9 8.7 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 PVD21892.1 - 9.3e-06 25.9 9.2 0.018 15.4 0.3 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD21892.1 - 0.1 12.4 10.0 0.34 10.7 3.4 3.7 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 PVD21892.1 - 0.34 11.6 1.8 1e+02 4.1 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat RNA_pol_3_Rpc31 PF11705.8 PVD21892.1 - 6 7.0 15.4 11 6.2 15.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EXS PF03124.14 PVD21893.1 - 3.4e-105 352.0 25.6 5e-105 351.5 25.6 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 PVD21893.1 - 2.1e-27 97.1 21.4 2.6e-12 47.4 6.0 3.2 1 1 2 3 3 3 3 SPX domain Ndufs5 PF10200.9 PVD21893.1 - 0.062 13.6 0.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PDZ PF00595.24 PVD21895.1 - 5.5e-08 33.1 0.1 1.3e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Fibrinogen_C PF00147.18 PVD21896.1 - 2.8e-14 53.5 0.1 4.5e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain E1_DerP2_DerF2 PF02221.15 PVD21897.1 - 7.4e-07 29.7 0.0 0.00016 22.1 0.0 2.1 1 1 1 2 2 2 2 ML domain zf-C3HC4_4 PF15227.6 PVD21898.1 - 5e-05 23.4 5.6 0.00012 22.2 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD21898.1 - 0.00061 19.7 5.2 0.0014 18.6 5.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD21898.1 - 0.008 16.0 5.9 0.022 14.6 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 PVD21898.1 - 0.043 14.0 2.1 0.12 12.5 2.1 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.6 PVD21898.1 - 0.048 14.0 5.1 0.13 12.7 5.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PVD21898.1 - 0.052 13.4 4.4 0.1 12.5 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21898.1 - 0.13 12.1 4.7 0.25 11.2 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.20 PVD21898.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain Peptidase_M13_N PF05649.13 PVD21898.1 - 0.22 11.2 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 Prok-RING_4 PF14447.6 PVD21898.1 - 1.2 9.0 8.2 21 5.1 8.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RRN7 PF11781.8 PVD21898.1 - 2.5 7.9 4.7 15 5.4 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Actin PF00022.19 PVD21899.1 - 6.7e-153 509.1 0.0 2.2e-152 507.4 0.0 1.6 1 1 0 1 1 1 1 Actin FAP PF07174.11 PVD21904.1 - 0.74 9.2 9.5 0.96 8.9 9.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Dicty_REP PF05086.12 PVD21905.1 - 0.57 8.1 4.4 0.66 7.9 4.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 PVD21905.1 - 8.1 4.5 17.8 11 4.1 17.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Zip PF02535.22 PVD21909.1 - 2.2 7.4 4.8 2.2 7.4 4.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter MCM_bind PF09739.9 PVD21909.1 - 2.9 6.2 4.9 2.9 6.2 4.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 PVD21909.1 - 9.8 4.8 10.0 11 4.7 10.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ig_3 PF13927.6 PVD21910.1 - 8.4e-34 116.0 0.8 4.7e-14 52.7 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD21910.1 - 1.9e-33 114.4 0.4 6.1e-14 51.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD21910.1 - 6.5e-24 83.9 0.7 1.2e-08 35.0 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD21910.1 - 7.1e-21 74.3 4.3 1.8e-09 37.8 0.1 3.2 2 1 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD21910.1 - 9.4e-13 48.3 4.5 0.0012 19.0 0.0 4.5 3 2 1 4 4 4 3 Immunoglobulin V-set domain V-set_CD47 PF08204.11 PVD21910.1 - 0.00022 21.2 0.1 0.023 14.6 0.0 2.7 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 PVD21910.1 - 0.00073 19.6 0.7 0.6 10.2 0.0 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD21910.1 - 0.003 17.6 0.1 0.096 12.8 0.0 2.9 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD21910.1 - 0.0043 17.3 0.1 1.9 8.8 0.0 3.3 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD21910.1 - 0.0085 16.5 0.2 6 7.4 0.1 3.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD21910.1 - 0.02 14.4 0.1 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD21910.1 - 0.041 13.9 0.1 4.9 7.2 0.0 3.0 3 1 0 3 3 3 0 C17orf99 Ig domain Rotamase PF00639.21 PVD21911.1 - 4.4e-25 88.5 0.0 6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PVD21911.1 - 6.7e-23 81.4 0.0 8.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 PVD21911.1 - 5.9e-10 39.1 0.3 1.1e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 PVD21911.1 - 0.0055 17.5 0.0 0.0075 17.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Stealth_CR4 PF17103.5 PVD21911.1 - 0.049 13.5 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Mito_carr PF00153.27 PVD21912.1 - 2.8e-76 251.5 1.3 1.1e-26 92.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 PVD21912.1 - 8.8e-21 74.1 7.9 4.3e-13 49.5 0.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD21912.1 - 2.6e-19 67.3 10.0 5.7e-06 25.5 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD21912.1 - 1.3e-18 65.3 9.7 7.4e-05 22.4 0.3 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PVD21912.1 - 6.9e-13 47.5 12.8 4.2e-05 22.8 0.3 4.8 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD21912.1 - 1e-07 31.6 8.3 0.00027 20.7 0.6 4.2 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD21912.1 - 2.4e-06 27.9 3.3 0.0077 16.5 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 PVD21912.1 - 0.00072 19.5 2.0 0.21 11.5 0.1 3.0 1 1 2 3 3 3 2 Caleosin related protein EF-hand_10 PF14788.6 PVD21912.1 - 0.0068 16.3 3.0 1.7 8.5 0.0 3.4 3 1 1 4 4 4 2 EF hand Dockerin_1 PF00404.18 PVD21912.1 - 0.013 15.7 3.2 1.7 8.9 0.7 2.5 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 PVD21912.1 - 1.5 8.8 7.1 4.9 7.2 2.6 3.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand FCH PF00611.23 PVD21913.1 - 2.9e-16 59.5 0.3 2.9e-16 59.5 0.3 3.5 3 2 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 PVD21913.1 - 2.5e-10 39.8 0.0 5.7e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD21913.1 - 4.6e-08 32.8 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 PVD21913.1 - 1.2e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.17 PVD21913.1 - 0.034 13.8 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SLATT_4 PF18186.1 PVD21913.1 - 0.34 10.5 9.5 0.06 13.0 2.0 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 Adhesin_E PF16747.5 PVD21916.1 - 0.026 14.6 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Surface-adhesin protein E TraT PF05818.12 PVD21918.1 - 3.8 7.1 10.4 5 6.7 10.4 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Keratin_2_head PF16208.5 PVD21918.1 - 4.2 7.5 31.5 6 7.0 31.5 1.3 1 0 0 1 1 1 0 Keratin type II head KH_1 PF00013.29 PVD21920.1 - 1.5e-71 236.1 16.9 2.4e-18 65.7 0.7 4.4 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 PVD21920.1 - 9.7e-19 67.0 8.9 0.00064 19.5 0.5 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 PVD21920.1 - 1.8e-15 56.1 6.2 1.8e-15 56.1 6.2 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1897) KH_4 PF13083.6 PVD21920.1 - 8.2e-11 41.6 10.8 0.00046 20.0 0.5 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 PVD21920.1 - 0.076 13.1 6.7 32 4.7 0.2 4.3 4 0 0 4 4 4 0 NusA-like KH domain Ldl_recept_a PF00057.18 PVD21921.1 - 5.2e-10 39.4 13.7 7.6e-10 38.8 13.7 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A INTS5_C PF14838.6 PVD21922.1 - 7.7e-148 494.2 3.6 9.8e-148 493.8 3.6 1.1 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 PVD21922.1 - 6.2e-69 231.8 0.0 1.1e-68 230.9 0.0 1.5 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DUF5560 PF17715.1 PVD21922.1 - 0.091 12.2 0.3 0.24 10.8 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5560) HEAT_EZ PF13513.6 PVD21922.1 - 0.13 12.9 0.1 1 10.0 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat TTL PF03133.15 PVD21923.1 - 2.4e-58 197.6 0.0 4.6e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 PVD21923.1 - 1.1e-09 38.0 0.0 0.00063 19.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 PVD21923.1 - 7e-07 28.7 0.0 0.061 12.6 0.0 3.0 2 2 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 PVD21923.1 - 0.0098 16.0 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 PVD21923.1 - 0.011 15.3 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Laminin_G_2 PF02210.24 PVD21924.1 - 9.9e-08 32.6 0.2 1.6e-07 32.0 0.2 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 PVD21924.1 - 0.0033 17.6 0.1 0.0048 17.1 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain DUF3959 PF13105.6 PVD21924.1 - 0.081 12.4 1.2 0.12 11.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) EGF PF00008.27 PVD21925.1 - 2.1e-142 462.7 609.8 1.9e-08 34.5 9.8 41.5 40 1 0 40 40 40 35 EGF-like domain hEGF PF12661.7 PVD21925.1 - 5.7e-91 296.4 515.8 5.9e-07 29.9 2.4 42.6 41 0 0 41 41 40 31 Human growth factor-like EGF Laminin_G_2 PF02210.24 PVD21925.1 - 2.1e-35 122.1 4.8 1.8e-12 48.0 0.2 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 PVD21925.1 - 1.2e-25 90.2 1.6 1.3e-08 35.1 0.1 3.3 3 0 0 3 3 3 3 Laminin G domain EGF_CA PF07645.15 PVD21925.1 - 2.9e-22 78.6 639.1 2.8e-06 27.4 9.1 41.3 22 10 19 41 41 37 22 Calcium-binding EGF domain EGF_2 PF07974.13 PVD21925.1 - 2.8e-10 40.4 655.2 0.0058 17.0 9.6 40.2 37 3 2 39 39 38 24 EGF-like domain cEGF PF12662.7 PVD21925.1 - 0.00085 19.2 0.7 0.00085 19.2 0.7 37.4 37 2 0 37 37 33 16 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD21925.1 - 0.0013 18.9 5.6 0.0013 18.9 5.6 41.2 29 8 11 40 40 39 16 EGF domain DUF313 PF03754.13 PVD21925.1 - 0.16 12.2 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Insulin_TMD PF17870.1 PVD21925.1 - 0.56 10.3 2.2 1.1 9.3 2.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Crystall PF00030.19 PVD21925.1 - 9.3 6.5 8.7 1.3 9.3 1.7 3.3 2 0 0 2 2 2 0 Beta/Gamma crystallin Endonuclease_NS PF01223.23 PVD21926.1 - 6.6e-65 219.1 0.0 8e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease EF-hand_8 PF13833.6 PVD21927.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.6 1 1 1 2 2 2 0 EF-hand domain pair Acyl_transf_3 PF01757.22 PVD21929.1 - 1.4e-05 24.4 6.6 1.5e-05 24.2 6.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Mtc PF03820.17 PVD21930.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier Ost4 PF10215.9 PVD21930.1 - 0.34 10.8 1.6 0.67 9.8 0.6 1.9 2 0 0 2 2 2 0 Oligosaccaryltransferase zf-RING_UBOX PF13445.6 PVD21931.1 - 1.4e-08 34.6 1.1 1.4e-08 34.6 1.1 4.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD21931.1 - 4.4e-08 33.1 3.9 4.4e-08 33.1 3.9 3.9 5 0 0 5 5 4 2 B-box zinc finger Filamin PF00630.19 PVD21931.1 - 3.8e-07 30.9 1.8 6.5e-07 30.1 0.0 2.3 2 1 0 2 2 1 1 Filamin/ABP280 repeat zf-C3HC4_2 PF13923.6 PVD21931.1 - 4.8e-07 29.5 2.6 4.8e-07 29.5 2.6 4.7 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21931.1 - 1.2e-06 28.2 1.2 1.2e-06 28.2 1.2 4.0 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21931.1 - 4.8e-06 26.3 1.8 4.8e-06 26.3 1.8 4.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21931.1 - 7e-06 26.1 2.8 7e-06 26.1 2.8 4.1 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD21931.1 - 7.7e-05 22.6 1.3 7.7e-05 22.6 1.3 4.3 4 1 0 4 4 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD21931.1 - 0.0022 17.8 1.9 0.0022 17.8 1.9 3.9 4 0 0 4 4 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD21931.1 - 0.0062 16.8 2.2 0.0062 16.8 2.2 4.5 4 0 0 4 4 2 1 Ring finger domain LMBR1 PF04791.16 PVD21931.1 - 0.082 11.8 0.0 0.2 10.5 0.0 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF5344 PF17279.2 PVD21931.1 - 0.33 11.6 4.3 0.97 10.1 4.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DUF948 PF06103.11 PVD21931.1 - 0.62 10.4 5.1 7.1 7.0 0.1 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Vps53_N PF04100.12 PVD21931.1 - 0.68 8.8 5.3 0.47 9.4 3.3 1.6 1 1 1 2 2 2 0 Vps53-like, N-terminal Spectrin PF00435.21 PVD21931.1 - 1.4 9.4 8.0 0.79 10.2 3.4 2.3 1 1 1 2 2 2 0 Spectrin repeat SKA2 PF16740.5 PVD21931.1 - 1.8 8.4 10.4 1.2 9.0 2.4 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 PVD21931.1 - 2.9 7.9 10.3 4.9 7.2 5.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L28e PF01778.17 PVD21932.1 - 6.7e-21 75.2 0.4 7.7e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Monellin PF09200.10 PVD21932.1 - 0.054 13.4 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Monellin PABP PF00658.18 PVD21933.1 - 4.1e-34 116.6 11.5 1.8e-12 47.2 0.3 3.3 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain Pox_H7 PF04787.12 PVD21933.1 - 0.088 13.3 0.4 2.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Late protein H7 RDM PF11002.8 PVD21933.1 - 0.18 11.8 1.4 23 5.1 0.0 3.0 3 0 0 3 3 3 0 RFPL defining motif (RDM) YlbD_coat PF14071.6 PVD21933.1 - 0.19 12.0 3.3 15 5.8 0.0 2.5 2 1 0 2 2 2 0 Putative coat protein DARPP-32 PF05395.12 PVD21933.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.1 1 1 1 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 ODR4-like PF14778.6 PVD21934.1 - 3.2e-88 296.2 0.0 3.8e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 4-like TUDOR PF00567.24 PVD21935.1 - 1.8e-11 44.1 0.0 4.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Tudor domain AlbA_2 PF04326.14 PVD21935.1 - 2.3e-09 37.7 0.0 6.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Putative DNA-binding domain Arm PF00514.23 PVD21935.1 - 0.00025 20.9 1.4 0.00066 19.6 0.2 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 PVD21935.1 - 0.048 13.6 0.0 0.25 11.3 0.0 2.1 1 1 1 2 2 2 0 Importin-beta N-terminal domain Proteasome PF00227.26 PVD21936.1 - 6.8e-51 172.5 0.1 8.5e-51 172.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 PVD21936.1 - 2.8e-14 52.2 1.1 2.8e-14 52.2 1.1 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal cNMP_binding PF00027.29 PVD21938.1 - 3.3e-20 72.0 0.5 4.1e-12 46.0 0.2 4.4 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Secretin_N PF03958.17 PVD21938.1 - 1.1 9.8 4.0 45 4.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain K_channel_TID PF07941.11 PVD21938.1 - 1.2 9.7 5.1 2.6 8.6 5.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ank_2 PF12796.7 PVD21939.1 - 1.3e-50 169.9 0.5 4.4e-15 56.0 0.1 5.8 4 3 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD21939.1 - 6.5e-42 141.4 6.7 3e-12 46.8 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD21939.1 - 7e-41 136.9 14.1 5.6e-06 26.6 0.0 9.8 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 PVD21939.1 - 3e-34 113.2 13.2 0.00065 20.0 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PVD21939.1 - 1.3e-32 111.4 10.1 2.5e-08 34.0 0.0 7.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD21939.1 - 3.6e-05 24.0 1.5 0.00013 22.2 1.5 2.1 1 0 0 1 1 1 1 SOCS box WAP PF00095.21 PVD21940.1 - 8.7e-14 51.6 27.0 2.9e-10 40.4 8.8 10.0 9 3 0 9 9 9 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' SEA PF01390.20 PVD21940.1 - 3.5e-09 36.7 0.3 2.3e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 SEA domain Ldl_recept_a PF00057.18 PVD21940.1 - 1e-06 28.8 12.1 1e-06 28.8 12.1 8.4 10 0 0 10 10 10 1 Low-density lipoprotein receptor domain class A DUF3827 PF12877.7 PVD21940.1 - 0.00015 20.3 0.1 0.00023 19.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.6 PVD21940.1 - 0.00055 19.9 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 PVD21940.1 - 0.033 14.0 0.3 0.077 12.8 0.3 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Protocadherin PF08374.11 PVD21940.1 - 0.086 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 PVD21940.1 - 0.093 13.6 0.2 0.32 11.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 PVD21940.1 - 0.18 12.5 1.9 0.41 11.4 0.1 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal BetaGal_dom3 PF13363.6 PVD21940.1 - 0.64 9.6 3.0 12 5.5 0.1 3.2 3 0 0 3 3 3 0 Beta-galactosidase, domain 3 Fibrinogen_C PF00147.18 PVD21941.1 - 6.5e-11 42.4 0.0 1.7e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CBM_14 PF01607.24 PVD21941.1 - 0.073 13.2 0.8 2.1 8.6 0.4 2.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain EGF_2 PF07974.13 PVD21941.1 - 0.86 10.0 8.0 0.87 10.0 0.6 3.1 3 0 0 3 3 3 0 EGF-like domain S4 PF01479.25 PVD21942.1 - 4.5e-11 42.3 1.7 1.4e-10 40.7 1.7 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PVD21942.1 - 4.4e-07 30.7 2.1 4.9e-07 30.6 0.9 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Dynamin_M PF01031.20 PVD21943.1 - 4e-80 269.1 2.7 4e-80 269.1 2.7 2.1 2 1 0 2 2 2 1 Dynamin central region GED PF02212.18 PVD21943.1 - 1.9e-23 82.4 2.8 1.9e-23 82.4 2.8 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.23 PVD21943.1 - 9.5e-22 77.8 0.3 3.2e-21 76.1 0.1 2.1 2 0 0 2 2 2 1 Dynamin family PH PF00169.29 PVD21943.1 - 4.7e-11 43.1 0.5 9.6e-11 42.1 0.5 1.5 1 0 0 1 1 1 1 PH domain RVT_1 PF00078.27 PVD21943.1 - 0.055 13.0 0.3 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) BAT2_N PF07001.11 PVD21944.1 - 1.2e-17 65.1 11.8 1.2e-17 65.1 11.8 12.7 12 3 1 15 15 15 1 BAT2 N-terminus Nuc_deoxyri_tr2 PF15891.5 PVD21945.1 - 4.5e-36 123.4 0.0 5.3e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like DUF3945 PF13101.6 PVD21945.1 - 0.0097 15.6 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3945) EF-hand_6 PF13405.6 PVD21945.1 - 0.01 15.7 0.3 8.2 6.7 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 PVD21945.1 - 0.067 13.6 0.2 5.3 7.6 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair THAP PF05485.12 PVD21946.1 - 0.55 11.2 0.1 0.55 11.2 0.1 3.1 2 1 0 2 2 2 0 THAP domain Pro_isomerase PF00160.21 PVD21947.1 - 4.5e-49 166.8 0.0 9.3e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gln-synt_C PF00120.24 PVD21947.1 - 1.4e-16 60.5 0.0 2.1e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PVD21947.1 - 1.1e-13 50.7 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain O-FucT PF10250.9 PVD21948.1 - 2e-65 221.7 0.0 3.7e-54 184.7 0.0 2.0 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase CARD PF00619.21 PVD21949.1 - 4.7e-13 49.0 0.1 1.1e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Caspase recruitment domain DUF3972 PF13118.6 PVD21950.1 - 0.0055 17.1 4.3 0.0085 16.5 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) ADIP PF11559.8 PVD21950.1 - 0.011 15.9 11.5 0.015 15.4 11.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 PVD21950.1 - 0.021 13.7 11.7 0.03 13.2 11.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF29 PF01724.16 PVD21950.1 - 0.023 14.9 2.4 0.029 14.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 Bacillus_HBL PF05791.11 PVD21950.1 - 0.076 12.8 2.9 0.11 12.3 2.9 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) APG6_N PF17675.1 PVD21950.1 - 0.087 13.4 12.3 0.049 14.2 9.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 PVD21950.1 - 0.088 12.6 7.6 0.11 12.3 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YbfN PF13982.6 PVD21950.1 - 0.094 13.0 0.5 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 YbfN-like lipoprotein Flagellar_rod PF05149.12 PVD21950.1 - 0.095 12.2 7.8 0.13 11.7 7.8 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein CREPT PF16566.5 PVD21950.1 - 0.15 12.2 9.8 0.13 12.5 8.3 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CorA PF01544.18 PVD21950.1 - 0.17 11.2 4.3 0.21 10.9 4.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GAS PF13851.6 PVD21950.1 - 0.19 11.1 12.3 2 7.8 12.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2408 PF10303.9 PVD21950.1 - 0.2 12.2 6.3 0.25 11.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FapA PF03961.13 PVD21950.1 - 0.22 10.1 4.6 0.24 10.0 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 PVD21950.1 - 0.32 11.6 5.1 1.5 9.4 4.3 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1216 PF06746.11 PVD21950.1 - 0.35 10.9 5.5 1.1 9.2 3.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1216) DUF1664 PF07889.12 PVD21950.1 - 0.36 10.9 4.4 1.2 9.2 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 PVD21950.1 - 0.39 11.4 6.8 0.2 12.3 2.8 2.2 1 1 1 2 2 2 0 SlyX DUF1043 PF06295.12 PVD21950.1 - 0.39 10.7 7.2 0.88 9.6 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Seryl_tRNA_N PF02403.22 PVD21950.1 - 0.41 10.9 8.8 1.2 9.4 8.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 PVD21950.1 - 0.66 10.9 10.6 1 10.3 10.6 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 PVD21950.1 - 0.74 9.1 9.3 1.4 8.1 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AATF-Che1 PF13339.6 PVD21950.1 - 0.76 10.5 7.6 24 5.6 7.6 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-H PF05837.12 PVD21950.1 - 0.83 10.1 10.9 2.4 8.6 10.6 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) KxDL PF10241.9 PVD21950.1 - 1.4 9.3 8.7 0.48 10.7 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein GrpE PF01025.19 PVD21950.1 - 2 8.0 8.4 3.3 7.3 8.3 1.5 1 1 0 1 1 1 0 GrpE HAUS6_N PF14661.6 PVD21950.1 - 2.1 7.9 9.4 0.49 9.9 2.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 PVD21950.1 - 4.3 6.5 6.7 4.9 6.3 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF5320 PF17253.2 PVD21950.1 - 8 7.6 6.8 1.5 10.0 1.7 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Ax_dynein_light PF10211.9 PVD21951.1 - 1.2e-09 38.3 4.8 1.2e-09 38.3 4.8 3.8 3 1 0 3 3 3 2 Axonemal dynein light chain DUF16 PF01519.16 PVD21951.1 - 4.6 7.8 9.2 2 8.9 0.6 3.8 3 1 0 3 3 3 0 Protein of unknown function DUF16 BRE1 PF08647.11 PVD21951.1 - 6.1 7.0 24.6 0.033 14.3 3.7 3.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase SURF2 PF05477.11 PVD21952.1 - 4.1e-43 147.8 9.0 4.9e-43 147.5 9.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) G-alpha PF00503.20 PVD21953.1 - 1.6e-65 221.6 0.0 4e-65 220.3 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD21953.1 - 0.00056 19.4 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-C3HC4_3 PF13920.6 PVD21954.1 - 2e-07 30.8 11.8 2e-07 30.8 11.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD21954.1 - 3.9e-06 26.6 14.9 3.9e-06 26.6 14.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD21954.1 - 3.3e-05 24.0 10.5 0.0002 21.4 3.2 3.8 5 0 0 5 5 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD21954.1 - 4.4e-05 23.4 13.3 4.4e-05 23.4 13.3 2.8 3 0 0 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD21954.1 - 9.6e-05 22.2 14.6 9.6e-05 22.2 14.6 3.9 3 2 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD21954.1 - 0.00017 21.9 15.3 0.00017 21.9 15.3 3.5 4 0 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD21954.1 - 0.00051 19.9 12.5 0.00051 19.9 12.5 3.6 4 1 1 5 5 2 1 zinc-RING finger domain IFT57 PF10498.9 PVD21954.1 - 0.00094 18.2 1.3 0.0014 17.7 1.3 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Neuralized PF07177.12 PVD21954.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Neuralized ApoLp-III PF07464.11 PVD21954.1 - 0.0052 16.9 3.8 0.0093 16.1 3.8 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) SHE3 PF17078.5 PVD21954.1 - 0.0091 15.7 0.3 0.019 14.7 0.3 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF948 PF06103.11 PVD21954.1 - 0.012 15.8 2.9 0.18 12.1 1.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PVD21954.1 - 0.013 14.4 4.0 0.019 13.8 4.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ArfGap PF01412.18 PVD21954.1 - 0.015 15.4 3.5 0.015 15.4 3.5 3.7 3 1 0 3 3 3 0 Putative GTPase activating protein for Arf FAM184 PF15665.5 PVD21954.1 - 0.021 14.6 7.4 0.035 13.9 7.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B LMBR1 PF04791.16 PVD21954.1 - 0.043 12.7 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin_1 PF12718.7 PVD21954.1 - 0.049 13.8 7.6 0.11 12.7 7.6 1.5 1 0 0 1 1 1 0 Tropomyosin like AAA_13 PF13166.6 PVD21954.1 - 0.073 11.7 2.6 0.11 11.1 2.6 1.3 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 PVD21954.1 - 0.08 12.3 5.8 0.16 11.3 5.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 PVD21954.1 - 0.11 11.8 1.6 0.18 11.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 PVD21954.1 - 0.13 12.1 14.0 0.32 10.9 14.0 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 PVD21954.1 - 0.25 11.4 9.3 0.46 10.5 9.0 1.5 1 1 0 1 1 1 0 Laminin Domain II OmpH PF03938.14 PVD21954.1 - 0.41 11.0 3.3 0.63 10.4 3.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 PVD21954.1 - 0.42 10.7 1.2 1.2 9.1 1.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 PVD21954.1 - 0.54 10.4 2.9 1.1 9.4 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1690 PF07956.11 PVD21954.1 - 1.4 9.3 8.9 46 4.4 6.9 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF1664 PF07889.12 PVD21954.1 - 3.2 7.8 5.7 3.6 7.6 2.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) G-patch PF01585.23 PVD21955.1 - 1.5e-09 37.6 0.8 2.7e-09 36.8 0.8 1.4 1 0 0 1 1 1 1 G-patch domain TUDOR PF00567.24 PVD21955.1 - 0.00021 21.3 0.1 0.00059 19.9 0.1 1.7 1 0 0 1 1 1 1 Tudor domain zf_CCCH_4 PF18345.1 PVD21955.1 - 0.051 13.7 3.6 0.25 11.4 3.6 2.0 1 1 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 PVD21955.1 - 0.11 12.4 5.2 0.26 11.1 5.2 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger Agenet PF05641.12 PVD21955.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Agenet domain zf-CCCH PF00642.24 PVD21955.1 - 0.21 11.5 4.3 0.41 10.6 4.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PVD21955.1 - 1.2 9.7 3.1 2.1 8.9 3.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Homeodomain PF00046.29 PVD21960.1 - 0.0066 16.3 2.6 0.012 15.5 2.6 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 PVD21963.1 - 4.7e-35 119.6 19.7 2e-17 63.1 3.1 2.3 2 0 0 2 2 2 2 LIM domain TNFR_c6 PF00020.18 PVD21963.1 - 0.021 15.2 12.4 6.5 7.3 0.3 3.6 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Cytochrome_C7 PF14522.6 PVD21963.1 - 0.15 12.0 16.4 0.36 10.9 6.5 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 PVD21963.1 - 1.5 9.2 13.1 13 6.2 12.2 2.2 1 1 1 2 2 2 0 Class III cytochrome C family DZR PF12773.7 PVD21963.1 - 3.6 7.7 15.0 2.5e+02 1.8 0.0 3.6 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 PVD21963.1 - 8.2 7.0 14.8 2.1e+02 2.4 14.8 2.5 1 1 0 1 1 1 0 Cytochrome c3 BAF250_C PF12031.8 PVD21965.1 - 0.12 11.7 0.3 0.15 11.3 0.3 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Atrophin-1 PF03154.15 PVD21965.1 - 0.27 9.5 6.4 0.31 9.3 6.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family SR-25 PF10500.9 PVD21965.1 - 0.5 9.9 13.0 0.71 9.4 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3915 PF13054.6 PVD21965.1 - 0.6 10.1 6.3 1.2 9.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Peptidase_S49_N PF08496.10 PVD21965.1 - 0.69 10.0 7.5 0.94 9.5 7.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 PVD21965.1 - 8.6 5.1 10.4 11 4.8 10.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_16 PF13191.6 PVD21968.1 - 0.0016 18.8 0.0 0.035 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 PVD21968.1 - 0.0053 17.1 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD21968.1 - 0.0076 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 PVD21968.1 - 0.039 14.2 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD21968.1 - 0.051 12.8 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 PVD21968.1 - 0.17 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 PVD21968.1 - 0.2 12.1 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 PVD21968.1 - 0.21 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4094 PF13334.6 PVD21970.1 - 0.16 12.4 0.8 0.34 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Innexin PF00876.18 PVD21971.1 - 5.3e-54 183.8 22.1 3.6e-52 177.8 18.6 2.3 1 1 1 2 2 2 2 Innexin Neuralized PF07177.12 PVD21971.1 - 1.9e-22 79.9 0.1 3.7e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Neuralized zf-B_box PF00643.24 PVD21971.1 - 0.0024 18.0 6.1 0.0024 18.0 6.1 2.6 2 0 0 2 2 2 2 B-box zinc finger RE_SacI PF09566.10 PVD21971.1 - 0.12 12.1 1.6 0.44 10.3 0.4 2.3 3 0 0 3 3 3 0 SacI restriction endonuclease Homeodomain PF00046.29 PVD21972.1 - 1.1e-10 41.1 2.1 2e-10 40.4 2.1 1.4 1 0 0 1 1 1 1 Homeodomain Lectin_C PF00059.21 PVD21973.1 - 3.8e-07 30.8 0.0 8.9e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Lectin C-type domain DUF2418 PF10332.9 PVD21973.1 - 0.24 12.0 2.8 0.53 10.8 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Lectin_C PF00059.21 PVD21974.1 - 3.5e-07 30.9 0.0 6.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Neuralized PF07177.12 PVD21975.1 - 6.4e-13 49.0 0.0 1.8e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Neuralized zf-C3HC4 PF00097.25 PVD21975.1 - 3.8e-09 36.3 11.6 3.8e-09 36.3 11.6 3.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21975.1 - 3.5e-08 33.2 8.1 3.5e-08 33.2 8.1 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD21975.1 - 6.6e-06 26.2 32.2 4.7e-05 23.4 7.5 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD21975.1 - 9.8e-06 25.8 10.3 9.8e-06 25.8 10.3 3.8 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD21975.1 - 1.1e-05 25.1 9.8 1.1e-05 25.1 9.8 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD21975.1 - 1.5e-05 24.9 10.7 9.3e-05 22.4 10.7 2.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD21975.1 - 5e-05 23.1 9.3 5e-05 23.1 9.3 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21975.1 - 8.4e-05 22.6 10.6 8.4e-05 22.6 10.6 3.5 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD21975.1 - 0.00092 19.1 9.9 0.00092 19.1 9.9 3.7 3 0 0 3 3 2 1 zinc-RING finger domain SesA PF17107.5 PVD21975.1 - 0.038 14.2 0.3 0.07 13.3 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LMBR1 PF04791.16 PVD21975.1 - 0.05 12.5 2.6 0.022 13.7 0.4 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Fez1 PF06818.15 PVD21975.1 - 1.1 9.7 6.0 15 6.0 6.3 2.1 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 PVD21975.1 - 2.3 8.3 5.0 2.1 8.4 1.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein zf-Nse PF11789.8 PVD21975.1 - 2.6 7.9 10.8 4.9 7.1 9.5 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Neuralized PF07177.12 PVD21976.1 - 9.5e-13 48.4 0.1 1.2e-12 48.1 0.1 1.1 1 0 0 1 1 1 1 Neuralized zf-C3HC4 PF00097.25 PVD21977.1 - 1.8e-10 40.5 8.1 1.8e-10 40.5 8.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD21977.1 - 4.1e-09 36.3 4.0 4.1e-09 36.3 4.0 3.5 4 1 0 4 4 4 1 RING-type zinc-finger zf-B_box PF00643.24 PVD21977.1 - 1.1e-08 35.1 17.6 8.5e-06 25.8 6.6 4.3 5 0 0 5 5 5 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD21977.1 - 1.4e-08 34.4 37.2 2.7e-08 33.5 8.3 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD21977.1 - 3.1e-08 33.8 8.7 3.1e-08 33.8 8.7 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD21977.1 - 6e-07 29.2 7.5 6e-07 29.2 7.5 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD21977.1 - 9.7e-07 28.6 8.5 9.7e-07 28.6 8.5 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD21977.1 - 1.2e-06 28.4 8.1 1.2e-06 28.4 8.1 4.5 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD21977.1 - 3.1e-06 27.2 6.8 3.1e-06 27.2 6.8 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PVD21977.1 - 0.00059 20.1 6.4 0.00059 20.1 6.4 3.8 3 2 0 3 3 2 1 RING-H2 zinc finger domain zf-Nse PF11789.8 PVD21977.1 - 0.0064 16.3 6.1 0.0064 16.3 6.1 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF836 PF05768.14 PVD21977.1 - 5.6 7.4 8.5 50 4.4 0.5 3.5 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) zf-C3HC4 PF00097.25 PVD21978.1 - 7e-10 38.6 7.6 7e-10 38.6 7.6 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD21978.1 - 1.5e-08 34.6 5.9 1.4e-07 31.4 6.0 2.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD21978.1 - 6.2e-08 32.8 7.9 6.2e-08 32.8 7.9 4.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD21978.1 - 8.5e-08 31.9 6.7 8.5e-08 31.9 6.7 4.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD21978.1 - 5.1e-07 29.7 17.0 3.7e-05 23.8 6.0 4.9 5 1 0 5 5 4 2 B-box zinc finger Neuralized PF07177.12 PVD21978.1 - 1.1e-06 28.7 0.0 1.5e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Neuralized Prok-RING_4 PF14447.6 PVD21978.1 - 1.5e-06 28.0 8.3 1.5e-06 28.0 8.3 5.2 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD21978.1 - 2.2e-06 27.4 7.7 2.2e-06 27.4 7.7 4.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Ig_3 PF13927.6 PVD21978.1 - 3.8e-05 24.2 0.7 0.24 12.0 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD21978.1 - 5.1e-05 23.4 0.9 0.4 10.9 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain zf-RING_5 PF14634.6 PVD21978.1 - 8.3e-05 22.5 7.8 8.3e-05 22.5 7.8 4.8 4 1 1 5 5 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD21978.1 - 9.9e-05 22.4 8.4 9.9e-05 22.4 8.4 3.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING ig PF00047.25 PVD21978.1 - 0.00052 20.1 0.3 1.7 8.9 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain zf-rbx1 PF12678.7 PVD21978.1 - 0.00079 19.7 3.9 0.00079 19.7 3.9 4.5 4 0 0 4 4 4 1 RING-H2 zinc finger domain I-set PF07679.16 PVD21978.1 - 0.0067 16.5 0.0 5.4 7.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD21978.1 - 0.017 15.4 0.9 9.4 6.7 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 PVD21978.1 - 0.027 14.5 0.0 3.3 7.8 0.0 2.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain zf-Nse PF11789.8 PVD21978.1 - 0.037 13.9 8.2 0.031 14.1 5.1 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Med4 PF10018.9 PVD21978.1 - 2 8.1 3.9 1.4 8.6 0.9 2.2 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-RING_6 PF14835.6 PVD21978.1 - 5 7.1 17.3 0.3 11.0 4.8 3.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Neuralized PF07177.12 PVD21980.1 - 1.4e-15 57.6 0.0 3.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Neuralized zf-C3HC4 PF00097.25 PVD21980.1 - 2.4e-09 36.9 9.5 2.4e-09 36.9 9.5 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD21980.1 - 3e-09 36.6 7.0 3e-09 36.6 7.0 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD21980.1 - 9.9e-09 35.1 6.3 9.9e-09 35.1 6.3 3.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD21980.1 - 2.8e-07 30.7 9.4 2.8e-07 30.7 9.4 3.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD21980.1 - 5.6e-07 29.3 9.5 5.6e-07 29.3 9.5 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD21980.1 - 1.7e-06 28.0 7.8 1.7e-06 28.0 7.8 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD21980.1 - 2.5e-06 27.5 22.7 0.00014 22.0 5.4 4.4 4 1 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD21980.1 - 4.3e-05 23.4 9.4 4.3e-05 23.4 9.4 4.1 3 2 1 4 4 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD21980.1 - 0.00012 21.8 10.2 0.00012 21.8 10.2 3.6 3 2 1 4 4 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD21980.1 - 0.0043 16.8 2.2 0.0043 16.8 2.2 4.4 5 0 0 5 5 4 1 RING/Ubox like zinc-binding domain Serine_rich PF08824.10 PVD21980.1 - 0.019 15.0 1.1 0.039 13.9 1.1 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain zf-Nse PF11789.8 PVD21980.1 - 0.025 14.4 8.5 0.075 12.9 8.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Spc7 PF08317.11 PVD21980.1 - 0.12 11.2 5.0 0.21 10.4 5.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 PVD21980.1 - 0.15 12.5 5.9 0.32 11.4 5.9 1.5 1 0 0 1 1 1 0 Fez1 Zn-C2H2_12 PF18112.1 PVD21980.1 - 0.19 12.2 3.6 9.8 6.7 0.3 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 PVD21980.1 - 0.27 11.8 4.0 23 5.7 0.1 4.1 3 0 0 3 3 3 0 Zinc-finger double domain ParB PF08775.10 PVD21980.1 - 0.44 11.0 12.1 0.84 10.1 7.8 2.8 3 0 0 3 3 3 0 ParB family DUF1664 PF07889.12 PVD21980.1 - 0.44 10.6 6.4 1.9 8.5 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 PVD21980.1 - 0.45 10.9 6.1 1.5 9.3 6.1 1.9 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CREPT PF16566.5 PVD21980.1 - 3.5 7.8 7.7 8.7 6.5 7.7 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour zf-B_box PF00643.24 PVD21981.1 - 2.9e-09 36.9 25.6 3.5e-05 23.9 5.4 3.0 3 0 0 3 3 3 2 B-box zinc finger Spc7 PF08317.11 PVD21981.1 - 0.00073 18.5 2.6 0.0011 17.9 2.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Neuralized PF07177.12 PVD21981.1 - 0.0033 17.4 0.1 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Neuralized Serine_rich PF08824.10 PVD21981.1 - 0.016 15.2 2.6 0.033 14.2 2.6 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain Exonuc_VII_L PF02601.15 PVD21981.1 - 0.058 13.0 0.6 0.079 12.5 0.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 PVD21981.1 - 0.077 13.4 8.4 0.23 11.9 8.4 1.9 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ParB PF08775.10 PVD21981.1 - 0.17 12.4 10.3 0.37 11.3 9.3 1.9 2 0 0 2 2 2 0 ParB family LMBR1 PF04791.16 PVD21981.1 - 0.25 10.2 2.6 0.3 9.9 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 PVD21981.1 - 0.96 9.5 8.3 2.3 8.3 7.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 PVD21981.1 - 0.97 10.0 6.9 2.6 8.7 6.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 PVD21981.1 - 4.6 7.5 6.3 5.2 7.4 4.5 2.1 1 1 0 1 1 1 0 Haemolysin XhlA MFS_1 PF07690.16 PVD21982.1 - 1.5e-12 47.1 19.9 5.4e-12 45.3 20.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD21982.1 - 2.8e-07 29.8 7.0 4.7e-07 29.0 5.6 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 PVD21982.1 - 4.1e-05 22.3 5.1 0.00014 20.6 3.3 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein BING4CT PF08149.11 PVD21983.1 - 7.1e-35 118.7 0.0 4.9e-33 112.8 0.0 3.3 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 PVD21983.1 - 1.8e-05 25.4 1.6 0.00017 22.3 0.0 3.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD21983.1 - 9.8e-05 22.6 0.0 0.72 10.2 0.0 4.1 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PVD21983.1 - 0.00077 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.8 PVD21983.1 - 0.065 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ldh_1_C PF02866.18 PVD21984.1 - 0.085 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pkinase PF00069.25 PVD21985.1 - 1.1e-31 110.2 0.3 3e-22 79.2 0.3 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PVD21985.1 - 8e-11 41.7 0.1 5.3e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 PVD21985.1 - 0.022 14.4 0.2 0.75 9.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RVT_1 PF00078.27 PVD21985.1 - 0.054 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 PVD21985.1 - 0.081 12.8 0.2 0.41 10.5 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family EGF_2 PF07974.13 PVD21986.1 - 0.011 16.0 1.7 0.027 14.8 1.7 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 PVD21986.1 - 0.069 13.3 3.2 0.12 12.5 3.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain hEGF PF12661.7 PVD21986.1 - 0.15 12.7 2.1 0.15 12.7 2.1 2.4 3 0 0 3 3 3 0 Human growth factor-like EGF C1q PF00386.21 PVD21987.1 - 2.1e-17 63.5 0.0 3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 C1q domain ABC_tran_CTD PF16326.5 PVD21987.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain BRE1 PF08647.11 PVD21987.1 - 0.24 11.5 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fibrinogen_C PF00147.18 PVD21988.1 - 1.4e-13 51.1 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_4 PF14295.6 PVD21988.1 - 0.0083 16.0 1.8 0.021 14.7 1.8 1.7 1 0 0 1 1 1 1 PAN domain C1q PF00386.21 PVD21989.1 - 4.1e-09 36.7 0.0 6.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 C1q domain Sugarporin_N PF11471.8 PVD21989.1 - 0.0013 18.7 3.5 0.0025 17.7 3.5 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Fzo_mitofusin PF04799.13 PVD21989.1 - 0.07 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region EMP24_GP25L PF01105.24 PVD21989.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Caskin-tail PF16632.5 PVD21989.1 - 0.075 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Caskin Fibrinogen_C PF00147.18 PVD21990.1 - 1.4e-10 41.4 0.2 2e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 PVD21990.1 - 0.017 15.5 3.4 0.017 15.5 3.4 2.8 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 PVD21990.1 - 8.7 7.1 8.9 1.4 9.7 3.6 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Fibrinogen_C PF00147.18 PVD21991.1 - 3.6e-08 33.5 0.3 5.3e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 PVD21992.1 - 0.00023 21.0 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 PVD21993.1 - 0.11 12.9 3.9 0.23 11.8 3.9 1.5 1 0 0 1 1 1 0 EGF-like domain Fibrinogen_C PF00147.18 PVD21994.1 - 9.9e-10 38.6 0.1 1.3e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2985 PF11204.8 PVD21994.1 - 0.068 13.3 0.5 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) TF_Otx PF03529.13 PVD21994.1 - 0.23 11.9 1.1 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Otx1 transcription factor EGF_2 PF07974.13 PVD21994.1 - 0.27 11.7 3.9 0.73 10.3 3.9 1.8 1 0 0 1 1 1 0 EGF-like domain Fibrinogen_C PF00147.18 PVD21995.1 - 2.5e-15 56.9 1.3 2.5e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_4 PF14295.6 PVD21995.1 - 0.0027 17.6 1.3 0.0027 17.6 1.3 3.0 3 0 0 3 3 3 1 PAN domain Sec7_N PF12783.7 PVD21995.1 - 0.037 13.9 0.2 8.8 6.2 0.1 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PAN_1 PF00024.26 PVD21995.1 - 0.045 13.7 1.2 0.12 12.3 1.2 1.7 1 0 0 1 1 1 0 PAN domain UBA PF00627.31 PVD21996.1 - 2.9e-15 55.8 1.0 2.1e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 UBA/TS-N domain SHIPPO-rpt PF07004.12 PVD21997.1 - 9.6e-08 32.6 8.4 0.087 13.8 0.0 4.3 4 0 0 4 4 4 3 Sperm-tail PG-rich repeat PAX PF00292.18 PVD21998.1 - 4.2e-29 101.0 0.0 6.1e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 PVD21998.1 - 0.013 16.0 0.0 0.019 15.6 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain PhyH PF05721.13 PVD21999.1 - 1.1e-20 74.8 0.0 2.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_L29 PF00831.23 PVD22001.1 - 2.7e-19 68.9 2.9 2.7e-19 68.9 2.9 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 PVD22001.1 - 1.4 9.4 9.2 0.095 13.1 4.3 1.6 2 0 0 2 2 2 0 Snapin/Pallidin GRIP PF01465.20 PVD22002.1 - 8.9e-14 51.1 1.2 2.4e-13 49.7 1.2 1.8 1 0 0 1 1 1 1 GRIP domain ABC_tran_CTD PF16326.5 PVD22002.1 - 0.00056 20.1 4.7 0.00056 20.1 4.7 11.2 2 2 7 9 9 9 2 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 PVD22002.1 - 0.0032 17.6 8.3 0.0032 17.6 8.3 6.8 1 1 5 7 7 7 3 Tropomyosin like SlyX PF04102.12 PVD22002.1 - 0.0053 17.3 3.8 0.0053 17.3 3.8 13.1 4 4 10 14 14 14 2 SlyX VBS PF08913.10 PVD22002.1 - 0.016 15.7 7.4 0.089 13.2 5.1 2.9 2 0 0 2 2 2 0 Vinculin Binding Site GST_C_2 PF13410.6 PVD22002.1 - 1.3 9.1 3.4 13 5.9 0.1 3.8 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain AAA_13 PF13166.6 PVD22002.1 - 1.6 7.3 94.1 0.72 8.4 25.0 4.2 1 1 3 4 4 4 0 AAA domain Spc7 PF08317.11 PVD22002.1 - 5.2 5.9 131.0 0.035 13.0 19.9 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein Filament PF00038.21 PVD22002.1 - 8.5 5.9 117.9 0.04 13.5 2.6 6.3 1 1 3 4 4 4 0 Intermediate filament protein FKBP_N_2 PF18023.1 PVD22003.1 - 5.1e-07 29.8 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 BDBT FKBP like N-terminal Cnn_1N PF07989.11 PVD22004.1 - 5.5e-22 77.7 8.5 5.5e-22 77.7 8.5 23.2 9 2 14 23 23 23 2 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 PVD22004.1 - 0.00037 20.6 26.9 0.00037 20.6 26.9 15.3 5 2 8 14 14 14 3 Uncharacterised protein family (UPF0242) N-terminus DUF4250 PF14056.6 PVD22004.1 - 4.7 7.3 10.1 1.8 8.6 0.1 5.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Pkinase PF00069.25 PVD22005.1 - 3.5e-08 33.1 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22005.1 - 0.0033 16.7 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KAP PF05804.12 PVD22006.1 - 0 1131.9 23.3 0 1131.7 23.3 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 PVD22006.1 - 9.8e-09 35.0 2.6 0.21 11.7 0.0 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Peptidase_M50 PF02163.22 PVD22006.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M50 NopRA1 PF16201.5 PVD22006.1 - 0.027 14.0 1.1 2.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_M PF14666.6 PVD22006.1 - 0.041 13.6 0.3 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain FPL PF09758.9 PVD22006.1 - 0.15 12.1 9.9 0.055 13.5 1.8 3.5 4 0 0 4 4 4 0 Uncharacterised conserved protein HEAT PF02985.22 PVD22006.1 - 0.17 12.3 0.5 4.5 7.8 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat CTNNBL PF08216.11 PVD22006.1 - 0.94 9.7 6.7 2.7 8.2 0.1 3.8 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Methyltransf_PK PF05891.12 PVD22007.1 - 6.3e-76 254.7 0.0 7e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 PVD22007.1 - 3.3e-10 40.5 0.0 5.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD22007.1 - 1.7e-09 38.2 0.0 2.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD22007.1 - 2.9e-09 37.6 0.0 4.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD22007.1 - 9.7e-08 32.0 0.0 1.5e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PVD22007.1 - 3.8e-05 23.1 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 PVD22007.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 PVD22007.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 PVD22007.1 - 0.061 12.9 0.0 0.094 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Bin3 PF06859.12 PVD22007.1 - 0.15 12.7 0.0 0.36 11.5 0.0 1.8 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) VWC PF00093.18 PVD22008.1 - 5.5e-08 33.0 13.0 5.5e-08 33.0 13.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type C domain MAM PF00629.23 PVD22009.1 - 7.9e-57 191.7 8.4 5.1e-19 68.7 0.0 5.5 3 2 2 5 5 5 5 MAM domain, meprin/A5/mu Collagen PF01391.18 PVD22009.1 - 4.4e-19 68.0 50.0 3.6e-09 36.3 26.5 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WAP PF00095.21 PVD22009.1 - 5.1e-08 33.2 13.4 5.1e-08 33.2 13.4 3.2 3 0 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' I-set PF07679.16 PVD22009.1 - 1.6e-05 24.8 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD22009.1 - 0.00017 21.7 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD22009.1 - 0.0027 18.3 0.6 0.021 15.4 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD22009.1 - 0.13 12.6 0.7 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 PVD22009.1 - 0.15 12.3 0.4 1 9.5 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin V-set domain Conotoxin_I2 PF17557.2 PVD22009.1 - 0.89 9.7 9.7 3.8 7.7 9.7 2.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Exo_endo_phos_2 PF14529.6 PVD22010.1 - 1.2e-06 28.3 0.1 2.1e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HMG_box PF00505.19 PVD22011.1 - 0.041 14.3 1.6 0.041 14.3 1.6 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box zf-C3HC4_3 PF13920.6 PVD22012.1 - 8e-12 44.8 23.7 6.3e-10 38.8 9.6 2.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22012.1 - 7.7e-10 38.5 8.5 7.7e-10 38.5 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22012.1 - 7e-09 35.4 11.4 7e-09 35.4 11.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22012.1 - 7.8e-09 35.7 9.6 7.8e-09 35.7 9.6 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD22012.1 - 5.3e-07 29.4 9.7 5.3e-07 29.4 9.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22012.1 - 9.9e-07 28.8 8.9 9.9e-07 28.8 8.9 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD22012.1 - 3.1e-06 27.1 12.1 3.1e-06 27.1 12.1 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22012.1 - 0.00012 21.9 10.3 0.00012 21.9 10.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD22012.1 - 0.016 15.5 7.7 0.016 15.5 7.7 3.1 2 2 0 2 2 2 0 RING-H2 zinc finger domain zf-B_box PF00643.24 PVD22012.1 - 0.072 13.3 5.7 0.072 13.3 5.7 3.6 3 1 0 3 3 3 0 B-box zinc finger ArfGap PF01412.18 PVD22012.1 - 3.5 7.7 14.0 6.3 6.9 3.9 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Zn_ribbon_17 PF17120.5 PVD22012.1 - 7.7 6.2 17.2 0.92 9.2 6.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PVD22013.1 - 8.3e-13 48.0 26.3 3.2e-10 39.7 8.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22013.1 - 6.1e-10 38.8 6.3 6.1e-10 38.8 6.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22013.1 - 1.8e-09 37.8 8.2 1.8e-09 37.8 8.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22013.1 - 7.4e-09 35.5 9.0 7.4e-09 35.5 9.0 2.9 3 1 0 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22013.1 - 7.8e-09 35.3 8.4 7.8e-09 35.3 8.4 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22013.1 - 1.9e-07 30.8 8.8 1.9e-07 30.8 8.8 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22013.1 - 5.3e-06 26.5 8.2 5.3e-06 26.5 8.2 3.0 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22013.1 - 6.2e-05 22.9 7.9 6.2e-05 22.9 7.9 3.5 2 2 2 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22013.1 - 0.00029 20.9 3.3 0.00029 20.9 3.3 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 PVD22013.1 - 0.00042 20.4 8.5 0.00042 20.4 8.5 4.0 4 1 0 4 4 3 1 B-box zinc finger Rad50_zn_hook PF04423.14 PVD22013.1 - 0.0071 16.2 0.1 0.0071 16.2 0.1 2.7 3 0 0 3 3 3 1 Rad50 zinc hook motif AAA_32 PF13654.6 PVD22014.1 - 0.0034 16.2 1.0 0.0044 15.9 1.0 1.1 1 0 0 1 1 1 1 AAA domain ING PF12998.7 PVD22014.1 - 0.023 15.3 1.2 0.047 14.3 1.2 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF3829 PF12889.7 PVD22014.1 - 0.052 13.0 0.3 0.076 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Baculo_PEP_C PF04513.12 PVD22014.1 - 0.17 11.9 2.1 0.34 11.0 1.3 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PXA PF02194.15 PVD22014.1 - 0.24 11.3 3.5 5.8 6.9 3.5 2.6 1 1 0 1 1 1 0 PXA domain DUF1451 PF07295.11 PVD22014.1 - 0.42 10.6 5.8 1.8 8.6 0.2 2.6 1 1 2 3 3 3 0 Zinc-ribbon containing domain Plasmid_RAQPRD PF09686.10 PVD22014.1 - 0.51 10.6 2.3 0.6 10.4 0.2 2.0 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.12 PVD22014.1 - 9.3 6.3 7.3 3 7.9 3.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.25 PVD22015.1 - 3.2e-10 39.7 6.1 3.2e-10 39.7 6.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22015.1 - 2.7e-09 36.8 9.3 2.7e-09 36.8 9.3 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22015.1 - 4.3e-09 36.6 7.3 4.3e-09 36.6 7.3 3.6 3 0 0 3 3 3 1 Ring finger domain zf-B_box PF00643.24 PVD22015.1 - 1.2e-08 35.0 22.5 1.2e-05 25.4 9.5 4.4 5 2 0 5 5 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22015.1 - 1.8e-08 34.1 9.4 1.8e-08 34.1 9.4 3.6 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22015.1 - 4e-08 33.1 6.1 4e-08 33.1 6.1 2.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22015.1 - 3.1e-07 30.1 7.6 3.1e-07 30.1 7.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22015.1 - 5.6e-06 26.4 6.9 5.6e-06 26.4 6.9 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22015.1 - 9.3e-05 22.3 8.4 9.3e-05 22.3 8.4 4.0 3 1 1 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22015.1 - 0.0021 18.1 29.3 0.0087 16.1 8.0 3.5 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf Baculo_PEP_C PF04513.12 PVD22015.1 - 0.013 15.5 1.3 0.027 14.5 0.7 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-HIT PF04438.16 PVD22015.1 - 0.024 14.5 6.6 0.024 14.5 6.6 4.2 4 0 0 4 4 4 0 HIT zinc finger FlaF PF07309.11 PVD22015.1 - 0.025 14.6 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF HsbA PF12296.8 PVD22015.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A V_ATPase_I PF01496.19 PVD22015.1 - 0.06 11.3 0.9 0.072 11.0 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TelA PF05816.11 PVD22015.1 - 0.06 12.4 2.6 0.11 11.6 2.6 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF2935 PF11155.8 PVD22015.1 - 0.29 11.5 2.0 0.71 10.2 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Peptidase_M13 PF01431.21 PVD22016.1 - 5.5e-41 140.4 0.1 6.7e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 Abhydrolase_2 PF02230.16 PVD22016.1 - 0.11 12.3 0.3 0.6 9.9 0.3 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BNR_6 PF15899.5 PVD22016.1 - 0.3 11.3 1.3 0.49 10.6 0.2 1.9 2 0 0 2 2 2 0 BNR-Asp box repeat 4HB_MCP_1 PF12729.7 PVD22017.1 - 0.065 12.8 3.8 0.051 13.1 2.9 1.3 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction zf-B_box PF00643.24 PVD22018.1 - 9.6e-11 41.7 31.3 1.7e-06 28.0 3.3 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22018.1 - 3e-09 36.6 39.0 5.7e-09 35.7 9.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22018.1 - 6.1e-09 35.6 6.8 6.1e-09 35.6 6.8 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22018.1 - 1.3e-08 34.5 10.1 1.3e-08 34.5 10.1 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22018.1 - 2.7e-08 34.0 8.0 2.7e-08 34.0 8.0 3.7 4 0 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22018.1 - 3.4e-08 33.4 6.8 3.4e-08 33.4 6.8 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22018.1 - 1.6e-05 24.9 7.6 1.6e-05 24.9 7.6 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22018.1 - 0.0003 20.7 9.1 0.0003 20.7 9.1 4.0 3 1 1 4 4 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22018.1 - 0.0058 16.7 7.6 0.0058 16.7 7.6 3.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Arb1 PF09692.10 PVD22018.1 - 0.017 14.3 0.1 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ALMT PF11744.8 PVD22018.1 - 0.15 10.9 0.9 0.18 10.6 0.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3829 PF12889.7 PVD22018.1 - 0.18 11.2 0.2 0.78 9.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Baculo_PEP_C PF04513.12 PVD22018.1 - 0.22 11.6 2.4 0.49 10.4 1.3 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-HIT PF04438.16 PVD22018.1 - 1.5 8.8 18.8 0.1 12.5 6.0 3.8 3 0 0 3 3 3 0 HIT zinc finger zf-C3HC4_3 PF13920.6 PVD22019.1 - 1.2e-19 69.8 75.8 4.2e-09 36.1 9.3 5.2 5 0 0 5 5 5 4 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22019.1 - 1.4e-16 60.1 20.8 4.9e-10 39.1 6.1 5.2 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22019.1 - 6e-15 55.3 23.3 6.6e-09 36.0 7.3 5.3 5 0 0 5 5 4 2 Ring finger domain Prok-RING_4 PF14447.6 PVD22019.1 - 2.2e-14 53.0 27.7 2.5e-08 33.6 10.3 5.3 5 0 0 5 5 5 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22019.1 - 2e-12 46.9 25.1 3.3e-08 33.4 5.2 4.4 4 1 0 4 4 2 2 RING-type zinc-finger zf-B_box PF00643.24 PVD22019.1 - 1.2e-11 44.5 61.4 2.8e-05 24.2 3.7 6.2 5 2 0 5 5 5 3 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22019.1 - 2.5e-10 40.0 24.1 4.7e-07 29.5 7.6 5.2 5 0 0 5 5 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22019.1 - 5.4e-09 36.1 22.5 8.7e-06 25.8 6.9 5.0 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22019.1 - 1.9e-06 27.7 25.5 0.00014 21.7 8.4 6.1 5 2 1 6 6 4 2 zinc-RING finger domain ArfGap PF01412.18 PVD22019.1 - 4.1e-05 23.6 50.9 0.026 14.6 8.2 5.4 4 1 1 5 5 5 3 Putative GTPase activating protein for Arf Arb1 PF09692.10 PVD22019.1 - 0.0086 15.3 0.2 5 6.2 0.0 3.0 3 0 0 3 3 3 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Baculo_PEP_C PF04513.12 PVD22019.1 - 0.009 16.1 3.3 0.011 15.8 1.3 2.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 PVD22019.1 - 0.012 13.6 2.0 0.018 13.0 2.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_Mu_Gam PF07352.12 PVD22019.1 - 0.041 13.8 0.8 0.071 13.0 0.8 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Phasin PF05597.11 PVD22019.1 - 0.063 13.3 3.9 0.11 12.4 2.9 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ALMT PF11744.8 PVD22019.1 - 0.24 10.2 4.4 0.3 9.9 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-HIT PF04438.16 PVD22019.1 - 0.32 10.9 37.5 0.15 11.9 6.0 5.9 5 0 0 5 5 5 0 HIT zinc finger Syntaxin-6_N PF09177.11 PVD22019.1 - 0.66 10.6 7.0 1.1 9.9 0.2 2.8 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 PVD22019.1 - 2.4 8.2 9.6 3.6 7.7 4.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.25 PVD22020.1 - 1.3e-10 41.0 6.9 1.3e-10 41.0 6.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22020.1 - 4.4e-10 39.3 39.5 6.3e-10 38.8 10.1 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22020.1 - 2.9e-09 37.1 8.0 2.9e-09 37.1 8.0 3.7 4 0 0 4 4 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22020.1 - 8.1e-09 35.2 9.8 8.1e-09 35.2 9.8 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22020.1 - 1.7e-08 34.5 22.2 1.4e-05 25.1 9.6 4.1 4 1 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD22020.1 - 3.2e-08 33.4 6.2 3.2e-08 33.4 6.2 3.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22020.1 - 1.8e-07 30.9 7.7 1.8e-07 30.9 7.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22020.1 - 3e-06 27.3 7.0 3e-06 27.3 7.0 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22020.1 - 8.9e-05 22.4 9.3 8.9e-05 22.4 9.3 4.2 3 1 1 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22020.1 - 0.00064 19.8 27.2 0.0058 16.7 7.8 3.6 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf Baculo_PEP_C PF04513.12 PVD22020.1 - 0.00091 19.3 1.9 0.0016 18.5 1.9 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 PVD22020.1 - 0.0022 17.5 2.5 0.0036 16.8 2.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 ALMT PF11744.8 PVD22020.1 - 0.0043 15.9 0.8 0.0054 15.6 0.8 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter YscO-like PF16789.5 PVD22020.1 - 0.016 15.3 4.0 0.19 11.7 3.3 2.1 1 1 1 2 2 2 0 YscO-like protein DUF1664 PF07889.12 PVD22020.1 - 0.025 14.6 2.9 0.025 14.6 2.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD22020.1 - 0.032 14.1 0.5 0.079 12.8 0.5 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-rbx1 PF12678.7 PVD22020.1 - 0.036 14.4 6.2 0.036 14.4 6.2 4.2 4 1 0 4 4 3 0 RING-H2 zinc finger domain YlbD_coat PF14071.6 PVD22020.1 - 0.047 14.0 0.8 0.088 13.1 0.8 1.4 1 0 0 1 1 1 0 Putative coat protein Arb1 PF09692.10 PVD22020.1 - 0.048 12.8 0.4 3.4 6.7 0.2 2.1 2 0 0 2 2 2 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 TMPIT PF07851.13 PVD22020.1 - 0.075 12.3 0.5 0.1 11.9 0.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 PVD22020.1 - 0.081 12.9 1.8 0.18 11.8 1.7 1.6 1 1 0 1 1 1 0 Laminin Domain II V_ATPase_I PF01496.19 PVD22020.1 - 0.14 10.1 0.3 0.19 9.6 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RICH PF05062.12 PVD22020.1 - 0.24 11.8 2.4 0.28 11.5 0.8 1.9 1 1 0 2 2 2 0 RICH domain TBCA PF02970.16 PVD22020.1 - 0.29 11.5 4.3 1.3 9.4 4.2 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor A zf-HIT PF04438.16 PVD22020.1 - 0.41 10.5 18.9 0.13 12.2 7.2 3.8 3 0 0 3 3 3 0 HIT zinc finger COG2 PF06148.11 PVD22020.1 - 0.61 10.2 4.5 1.5 9.0 1.5 2.5 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 PVD22020.1 - 0.74 10.3 4.7 2.6 8.6 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 PVD22020.1 - 1.7 8.7 7.1 0.85 9.7 3.4 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C3HC4 PF00097.25 PVD22021.1 - 1.2e-16 60.3 21.2 6.8e-10 38.7 6.8 5.7 6 0 0 6 6 4 2 Zinc finger, C3HC4 type (RING finger) Neuralized PF07177.12 PVD22021.1 - 4.3e-16 59.3 0.0 9.8e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 Neuralized zf-B_box PF00643.24 PVD22021.1 - 5.7e-16 58.4 74.7 0.0002 21.4 6.6 6.9 6 0 0 6 6 6 4 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22021.1 - 2.6e-15 56.0 86.6 1.7e-08 34.2 9.4 6.1 6 0 0 6 6 4 4 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22021.1 - 1e-14 54.6 23.7 9.2e-09 35.5 7.8 5.9 6 0 0 6 6 3 2 Ring finger domain Prok-RING_4 PF14447.6 PVD22021.1 - 3.4e-13 49.2 27.6 6.6e-08 32.3 9.8 6.2 6 0 0 6 6 4 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22021.1 - 4.7e-11 42.3 24.7 5.9e-07 29.2 8.5 5.4 6 0 0 6 6 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22021.1 - 4.2e-09 36.3 30.6 4.9e-06 26.5 11.3 4.0 3 0 0 3 3 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22021.1 - 5e-07 29.8 23.9 8.9e-05 22.6 7.7 5.1 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22021.1 - 1.3e-05 25.1 24.9 0.00028 20.8 8.3 6.7 6 2 0 6 6 5 2 zinc-RING finger domain Baculo_PEP_C PF04513.12 PVD22021.1 - 0.00012 22.1 13.1 0.057 13.5 2.2 2.8 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus BfiI_DBD PF18243.1 PVD22021.1 - 0.00073 19.2 0.6 0.94 9.1 0.1 2.3 2 0 0 2 2 2 2 Metal-independent restriction enzyme BfiI DNA binding domain Spc7 PF08317.11 PVD22021.1 - 0.0014 17.5 15.5 0.012 14.5 2.2 3.1 3 0 0 3 3 3 2 Spc7 kinetochore protein Phasin PF05597.11 PVD22021.1 - 0.0029 17.6 8.6 0.14 12.1 0.5 3.1 3 0 0 3 3 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) HsbA PF12296.8 PVD22021.1 - 0.0063 16.9 1.1 0.48 10.9 0.1 3.0 2 1 1 3 3 3 1 Hydrophobic surface binding protein A ING PF12998.7 PVD22021.1 - 0.0073 16.9 11.2 0.4 11.3 2.0 3.1 3 0 0 3 3 2 2 Inhibitor of growth proteins N-terminal histone-binding ArfGap PF01412.18 PVD22021.1 - 0.011 15.8 61.7 0.2 11.7 7.6 6.6 4 2 2 6 6 6 0 Putative GTPase activating protein for Arf TelA PF05816.11 PVD22021.1 - 0.02 14.0 9.7 0.49 9.4 1.2 2.2 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) AGOG PF09171.10 PVD22021.1 - 0.025 13.9 0.4 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 N-glycosylase/DNA lyase DUF3829 PF12889.7 PVD22021.1 - 0.035 13.6 5.5 0.18 11.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF5601 PF18151.1 PVD22021.1 - 0.035 14.4 0.7 0.64 10.4 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF5601) ATP-synt_B PF00430.18 PVD22021.1 - 0.04 14.0 3.6 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF1512 PF07431.12 PVD22021.1 - 0.052 12.5 3.1 3.1 6.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) TPR_MLP1_2 PF07926.12 PVD22021.1 - 0.21 11.7 14.8 0.74 9.9 2.2 3.2 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein Cor1 PF04803.12 PVD22021.1 - 0.22 11.7 14.1 2.2 8.5 3.6 2.7 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region V_ATPase_I PF01496.19 PVD22021.1 - 0.27 9.1 7.5 0.73 7.7 1.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FH2 PF02181.23 PVD22021.1 - 0.33 10.0 12.1 0.38 9.8 3.7 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF1664 PF07889.12 PVD22021.1 - 0.33 11.0 16.8 4.3 7.4 1.8 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF87 PF01935.17 PVD22021.1 - 0.42 10.7 5.9 3.9 7.5 0.6 2.6 2 1 1 3 3 2 0 Helicase HerA, central domain ApoLp-III PF07464.11 PVD22021.1 - 0.44 10.6 11.8 1.8 8.7 1.1 3.0 3 0 0 3 3 2 0 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 PVD22021.1 - 0.5 9.8 16.6 0.69 9.3 2.5 2.7 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF3417 PF11897.8 PVD22021.1 - 0.54 10.7 2.8 27 5.3 0.2 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3417) ALMT PF11744.8 PVD22021.1 - 0.55 9.0 11.5 1.1 8.0 1.9 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Sec20 PF03908.13 PVD22021.1 - 0.78 9.7 6.1 12 5.9 0.6 2.9 2 0 0 2 2 2 0 Sec20 Apolipoprotein PF01442.18 PVD22021.1 - 0.8 9.5 15.2 0.59 10.0 2.7 3.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain TssC PF17541.2 PVD22021.1 - 0.96 8.2 8.3 0.57 9.0 1.0 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB FAM167 PF11652.8 PVD22021.1 - 0.97 10.0 11.8 1.1 9.7 0.3 4.4 3 2 1 4 4 4 0 FAM167 Allexi_40kDa PF05549.11 PVD22021.1 - 1.9 7.9 13.9 0.57 9.6 3.2 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein IKKbetaNEMObind PF12179.8 PVD22021.1 - 2.3 8.3 7.4 5 7.2 0.2 3.8 2 2 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain E2F_CC-MB PF16421.5 PVD22021.1 - 3.8 7.9 10.7 12 6.4 1.2 3.1 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Exonuc_VII_L PF02601.15 PVD22021.1 - 4.1 6.9 12.1 5.2 6.6 2.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit LMP PF04778.12 PVD22021.1 - 4.3 7.2 16.1 6.3 6.7 5.4 2.3 2 0 0 2 2 2 0 LMP repeated region Phage_Mu_Gam PF07352.12 PVD22021.1 - 4.7 7.1 8.6 16 5.4 0.6 2.5 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein COG2 PF06148.11 PVD22021.1 - 5.2 7.2 15.6 13 5.8 3.3 4.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 PVD22021.1 - 5.3 6.7 7.7 8.4 6.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TBCA PF02970.16 PVD22021.1 - 6.7 7.1 12.1 7.2 7.0 1.4 3.6 3 1 0 3 3 2 0 Tubulin binding cofactor A YlbD_coat PF14071.6 PVD22021.1 - 8.2 6.7 8.3 5.2 7.3 1.4 2.7 2 0 0 2 2 2 0 Putative coat protein zf-C3HC4 PF00097.25 PVD22022.1 - 1.8e-10 40.5 6.4 1.8e-10 40.5 6.4 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22022.1 - 1.2e-09 38.2 32.0 1.3e-05 25.3 8.3 4.3 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22022.1 - 2.6e-09 36.8 9.3 2.6e-09 36.8 9.3 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22022.1 - 1.3e-08 35.0 7.7 1.3e-08 35.0 7.7 4.4 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22022.1 - 2.7e-08 33.5 9.3 2.7e-08 33.5 9.3 3.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22022.1 - 6.5e-08 32.5 6.6 6.5e-08 32.5 6.6 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22022.1 - 3.7e-07 29.9 7.9 3.7e-07 29.9 7.9 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Neuralized PF07177.12 PVD22022.1 - 3.7e-07 30.2 0.0 7.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Neuralized zf-C3HC4_4 PF15227.6 PVD22022.1 - 2.4e-05 24.4 7.6 2.4e-05 24.4 7.6 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22022.1 - 0.00076 19.4 9.1 0.00076 19.4 9.1 4.4 4 1 0 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22022.1 - 0.025 14.6 30.8 0.31 11.1 7.9 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Mating_N PF12731.7 PVD22022.1 - 0.062 13.4 0.1 0.23 11.6 0.1 2.0 2 0 0 2 2 1 0 Mating-type protein beta 1 Laminin_G_3 PF13385.6 PVD22022.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF1640 PF07798.11 PVD22022.1 - 0.24 11.5 4.2 0.34 10.9 2.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 PVD22022.1 - 0.88 9.4 4.7 0.12 12.2 0.4 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SRA1 PF07304.11 PVD22022.1 - 6.6 6.5 10.5 1.8 8.3 1.8 3.4 3 1 1 4 4 4 0 Steroid receptor RNA activator (SRA1) zf-C3HC4 PF00097.25 PVD22023.1 - 9.5e-10 38.2 6.7 9.5e-10 38.2 6.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22023.1 - 9.8e-09 35.4 7.8 9.8e-09 35.4 7.8 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22023.1 - 3.2e-08 33.3 9.7 3.2e-08 33.3 9.7 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22023.1 - 7.5e-08 32.4 18.1 6.3e-05 23.0 4.9 4.1 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22023.1 - 1.6e-07 31.0 8.3 1.6e-07 31.0 8.3 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22023.1 - 1.7e-07 30.9 9.9 1.7e-07 30.9 9.9 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22023.1 - 1.1e-06 28.5 11.2 1.1e-06 28.5 11.2 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22023.1 - 1.8e-05 24.8 7.0 1.8e-05 24.8 7.0 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22023.1 - 0.00027 20.8 9.2 0.00027 20.8 9.2 4.4 4 1 1 5 5 4 1 zinc-RING finger domain FH2 PF02181.23 PVD22023.1 - 0.042 13.0 5.5 0.075 12.1 3.9 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain 5_nucleotid PF05761.14 PVD22023.1 - 0.17 10.8 4.4 0.078 11.9 2.3 1.5 1 1 0 1 1 1 0 5' nucleotidase family DUF3552 PF12072.8 PVD22023.1 - 0.49 9.8 12.8 0.027 13.9 7.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) PIN_8 PF18476.1 PVD22023.1 - 2.8 7.8 7.7 0.84 9.4 3.7 1.9 1 1 0 2 2 2 0 PIN like domain Baculo_PEP_C PF04513.12 PVD22023.1 - 3.1 7.8 7.9 2.8 8.0 0.5 2.5 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SWIRM-assoc_1 PF16495.5 PVD22023.1 - 3.3 7.7 11.5 0.6 10.1 0.9 3.0 3 1 0 3 3 3 0 SWIRM-associated region 1 ArfGap PF01412.18 PVD22023.1 - 3.8 7.6 33.3 0.19 11.8 5.2 4.1 3 1 1 4 4 4 0 Putative GTPase activating protein for Arf zf-B_box PF00643.24 PVD22024.1 - 3.9e-10 39.7 33.7 3.3e-05 24.0 5.1 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22024.1 - 8.9e-10 38.3 6.4 8.9e-10 38.3 6.4 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22024.1 - 2.7e-09 37.2 7.8 2.7e-09 37.2 7.8 3.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22024.1 - 3.8e-09 36.3 39.0 4.9e-09 35.9 9.4 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22024.1 - 2.4e-08 33.7 9.8 2.4e-08 33.7 9.8 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22024.1 - 3.8e-08 33.2 6.2 3.8e-08 33.2 6.2 2.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22024.1 - 4e-07 29.8 8.2 4e-07 29.8 8.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22024.1 - 2.6e-05 24.3 7.7 2.6e-05 24.3 7.7 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22024.1 - 8.3e-05 22.5 8.3 8.3e-05 22.5 8.3 3.8 3 1 1 4 4 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22024.1 - 0.0032 17.5 28.0 0.011 15.8 8.1 3.5 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf V_ATPase_I PF01496.19 PVD22024.1 - 0.045 11.7 0.6 0.058 11.3 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phasin PF05597.11 PVD22024.1 - 0.047 13.7 2.2 0.084 12.9 1.6 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TssC PF17541.2 PVD22024.1 - 0.092 11.6 1.0 0.13 11.0 1.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB ATP-synt_B PF00430.18 PVD22024.1 - 0.13 12.3 1.9 0.21 11.7 1.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1664 PF07889.12 PVD22024.1 - 0.97 9.5 7.6 2.4 8.2 4.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Plasmid_RAQPRD PF09686.10 PVD22024.1 - 2 8.7 6.2 0.84 9.9 0.6 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-HIT PF04438.16 PVD22024.1 - 3.4 7.6 20.0 0.063 13.2 6.5 3.7 3 0 0 3 3 3 0 HIT zinc finger zf-B_box PF00643.24 PVD22025.1 - 1.9e-09 37.5 18.1 3.9e-05 23.7 6.5 2.7 2 0 0 2 2 2 2 B-box zinc finger Med21 PF11221.8 PVD22025.1 - 0.0064 16.8 0.2 0.022 15.0 0.1 2.0 2 0 0 2 2 2 1 Subunit 21 of Mediator complex TPR_MLP1_2 PF07926.12 PVD22025.1 - 0.033 14.2 1.5 0.033 14.2 1.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_HK97_TLTM PF06120.11 PVD22025.1 - 0.055 12.6 3.1 0.08 12.1 3.1 1.4 1 0 0 1 1 1 0 Tail length tape measure protein ERCC4 PF02732.15 PVD22025.1 - 0.061 13.5 2.6 0.15 12.2 2.6 1.6 1 1 0 1 1 1 0 ERCC4 domain partial_CstF PF15861.5 PVD22025.1 - 0.075 12.8 0.9 0.19 11.6 0.9 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain CENP-Q PF13094.6 PVD22025.1 - 0.081 13.1 2.5 0.14 12.4 2.5 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.8 PVD22025.1 - 0.082 12.2 1.2 0.12 11.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 PVD22025.1 - 0.12 12.4 5.0 0.32 11.0 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 PVD22025.1 - 0.19 10.5 11.7 0.057 12.3 8.9 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 PVD22025.1 - 0.21 11.4 1.7 0.47 10.3 1.7 1.7 1 1 0 1 1 1 0 Septum formation initiator Cortex-I_coil PF09304.10 PVD22025.1 - 0.22 11.7 7.0 1.6 8.9 2.3 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil CLZ PF16526.5 PVD22025.1 - 0.37 11.2 4.0 0.34 11.3 0.5 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1640 PF07798.11 PVD22025.1 - 2.4 8.2 11.5 11 6.1 8.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) zf-UBP PF02148.19 PVD22025.1 - 2.4 8.5 11.0 8.1 6.9 11.0 2.0 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Fzo_mitofusin PF04799.13 PVD22025.1 - 5.1 6.6 8.9 6.5 6.3 1.4 2.4 1 1 1 2 2 2 0 fzo-like conserved region FlaC_arch PF05377.11 PVD22025.1 - 6.6 7.2 8.3 0.81 10.1 2.6 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ArfGap PF01412.18 PVD22025.1 - 7.5 6.7 19.7 0.074 13.1 7.5 2.7 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf-C3HC4 PF00097.25 PVD22026.1 - 2.8e-10 39.9 6.2 2.8e-10 39.9 6.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22026.1 - 5.6e-09 35.7 38.1 6.7e-09 35.5 9.4 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22026.1 - 9.3e-09 35.5 7.5 9.3e-09 35.5 7.5 3.8 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22026.1 - 4.9e-08 32.7 9.9 4.9e-08 32.7 9.9 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22026.1 - 1.1e-07 31.8 6.9 1.1e-07 31.8 6.9 3.1 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22026.1 - 1.2e-06 28.2 7.5 1.2e-06 28.2 7.5 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22026.1 - 5.6e-06 26.4 7.1 5.6e-06 26.4 7.1 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22026.1 - 1.3e-05 25.2 21.8 0.00054 20.1 9.6 4.0 4 1 0 4 4 3 2 B-box zinc finger zf-RING_5 PF14634.6 PVD22026.1 - 0.00061 19.7 8.8 0.00061 19.7 8.8 4.0 3 1 1 4 4 4 1 zinc-RING finger domain Halo_GVPC PF05465.13 PVD22026.1 - 0.004 17.4 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 Halobacterial gas vesicle protein C (GVPC) repeat Phasin PF05597.11 PVD22026.1 - 0.0043 17.1 1.8 0.0043 17.1 1.8 2.5 2 1 1 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) FAM184 PF15665.5 PVD22026.1 - 0.0077 16.0 4.4 0.0077 16.0 4.4 1.9 2 1 0 2 2 2 1 Family with sequence similarity 184, A and B NACHT_N PF17100.5 PVD22026.1 - 0.029 14.2 1.0 0.047 13.5 1.0 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Baculo_PEP_C PF04513.12 PVD22026.1 - 0.042 13.9 6.9 0.045 13.8 4.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 PVD22026.1 - 0.11 12.6 5.9 0.14 12.3 3.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Goodbye PF17109.5 PVD22026.1 - 0.11 13.0 0.9 3.7 8.0 0.1 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain YlbD_coat PF14071.6 PVD22026.1 - 0.28 11.4 2.4 0.57 10.4 2.4 1.5 1 0 0 1 1 1 0 Putative coat protein TMPIT PF07851.13 PVD22026.1 - 0.8 8.9 5.9 1.2 8.3 5.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 PVD22026.1 - 1 9.4 7.9 0.81 9.7 5.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 PVD22026.1 - 3.9 7.4 17.8 0.048 13.6 5.8 3.4 3 0 0 3 3 3 0 HIT zinc finger LMBR1 PF04791.16 PVD22026.1 - 5.9 5.7 4.7 7.4 5.4 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ArfGap PF01412.18 PVD22026.1 - 7.5 6.7 31.4 0.56 10.3 9.0 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf CLZ PF16526.5 PVD22026.1 - 7.9 6.9 8.3 7.4 7.0 0.1 3.5 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-RING_2 PF13639.6 PVD22027.1 - 2.9e-09 37.1 9.0 2.9e-09 37.1 9.0 4.1 5 0 0 5 5 3 1 Ring finger domain zf-B_box PF00643.24 PVD22027.1 - 7.9e-09 35.5 22.1 1.6e-05 24.9 4.9 4.3 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22027.1 - 9.7e-09 35.0 7.1 9.7e-09 35.0 7.1 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD22027.1 - 3.8e-08 33.0 8.9 3.8e-08 33.0 8.9 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22027.1 - 3.9e-08 33.0 10.0 3.9e-08 33.0 10.0 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22027.1 - 2.5e-07 30.6 7.5 2.5e-07 30.6 7.5 3.3 3 1 0 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22027.1 - 4.3e-07 29.7 9.9 4.3e-07 29.7 9.9 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22027.1 - 1.1e-05 25.4 7.6 1.1e-05 25.4 7.6 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22027.1 - 2.8e-05 24.0 8.0 2.8e-05 24.0 8.0 4.3 4 1 1 5 5 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22027.1 - 0.0052 16.9 8.3 0.0052 16.9 8.3 3.4 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf HsbA PF12296.8 PVD22027.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A TPR_MLP1_2 PF07926.12 PVD22027.1 - 0.021 14.9 3.4 0.031 14.3 2.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 PVD22027.1 - 0.021 15.1 1.5 0.042 14.1 1.5 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phasin PF05597.11 PVD22027.1 - 0.031 14.3 1.8 0.069 13.2 1.8 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spc24 PF08286.11 PVD22027.1 - 0.12 12.7 2.2 0.23 11.7 2.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FH2 PF02181.23 PVD22027.1 - 0.15 11.1 4.2 0.24 10.5 4.2 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain CENP-H PF05837.12 PVD22027.1 - 0.23 11.9 4.5 0.59 10.6 4.5 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 PVD22027.1 - 0.24 11.5 5.6 0.4 10.7 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 PVD22027.1 - 0.3 11.5 3.2 0.51 10.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) COG2 PF06148.11 PVD22027.1 - 0.38 10.8 7.1 0.33 11.0 4.7 2.1 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 PVD22027.1 - 0.6 9.3 3.3 0.87 8.8 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1465 PF07323.12 PVD22027.1 - 0.65 9.8 3.9 0.73 9.7 0.5 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1465) zf-HIT PF04438.16 PVD22027.1 - 0.99 9.3 20.0 0.039 13.8 7.2 3.9 3 0 0 3 3 3 0 HIT zinc finger NPV_P10 PF05531.12 PVD22027.1 - 1.6 9.3 5.8 21 5.6 1.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 PVD22027.1 - 2.1 8.8 4.8 0.77 10.2 0.3 2.5 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C3HC4 PF00097.25 PVD22028.1 - 8.5e-10 38.4 5.0 8.5e-10 38.4 5.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22028.1 - 2.1e-09 37.5 6.9 2.1e-09 37.5 6.9 3.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22028.1 - 2.4e-09 36.9 8.3 2.4e-09 36.9 8.3 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22028.1 - 7.1e-09 35.7 34.8 8.1e-05 22.7 6.2 3.8 3 1 0 3 3 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22028.1 - 8.3e-09 35.2 9.1 8.3e-09 35.2 9.1 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22028.1 - 2.4e-08 33.9 6.2 2.4e-08 33.9 6.2 2.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22028.1 - 3.6e-07 29.9 7.3 3.6e-07 29.9 7.3 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22028.1 - 5.1e-05 23.2 7.3 5.1e-05 23.2 7.3 3.8 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22028.1 - 5.8e-05 23.2 7.1 5.8e-05 23.2 7.1 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3829 PF12889.7 PVD22028.1 - 0.0042 16.6 0.6 0.0097 15.4 0.4 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3829) HsbA PF12296.8 PVD22028.1 - 0.0094 16.4 0.5 0.021 15.2 0.5 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A ING PF12998.7 PVD22028.1 - 0.019 15.5 2.4 0.048 14.2 1.9 2.0 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ArfGap PF01412.18 PVD22028.1 - 0.028 14.5 28.5 0.14 12.2 9.6 3.3 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-rbx1 PF12678.7 PVD22028.1 - 0.038 14.3 4.7 0.038 14.3 4.7 3.8 3 1 0 3 3 2 0 RING-H2 zinc finger domain Baculo_PEP_C PF04513.12 PVD22028.1 - 0.045 13.8 9.0 0.11 12.6 6.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM167 PF11652.8 PVD22028.1 - 0.075 13.5 0.5 0.075 13.5 0.5 2.6 2 1 0 2 2 2 0 FAM167 Apolipoprotein PF01442.18 PVD22028.1 - 0.15 11.9 4.3 0.32 10.8 4.2 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1465 PF07323.12 PVD22028.1 - 0.17 11.7 2.7 3.4 7.5 0.4 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1465) COG2 PF06148.11 PVD22028.1 - 0.18 11.9 6.6 0.39 10.8 1.4 2.7 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 PVD22028.1 - 0.25 9.2 2.6 0.55 8.1 2.5 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-HIT PF04438.16 PVD22028.1 - 0.57 10.1 17.6 0.13 12.2 6.3 3.7 3 0 0 3 3 3 0 HIT zinc finger DUF1664 PF07889.12 PVD22028.1 - 0.73 9.9 14.6 0.42 10.6 3.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 PVD22028.1 - 0.9 8.7 2.9 1.4 8.1 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.11 PVD22028.1 - 1.4 8.9 7.7 4.4 7.3 5.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 PVD22028.1 - 2.9 8.4 12.0 0.13 12.8 0.5 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.6 PVD22028.1 - 3.8 7.7 7.9 2.7 8.1 2.7 2.6 1 1 2 3 3 3 0 Up-regulated During Septation Plasmid_RAQPRD PF09686.10 PVD22028.1 - 6.7 7.0 5.7 2.2 8.6 0.4 2.7 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-B_box PF00643.24 PVD22029.1 - 3e-10 40.1 31.8 1.6e-05 25.0 3.5 4.1 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22029.1 - 1.7e-09 37.4 6.5 1.7e-09 37.4 6.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22029.1 - 4.5e-09 36.0 39.5 6.7e-09 35.5 9.3 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22029.1 - 6.2e-09 36.1 8.0 6.2e-09 36.1 8.0 3.9 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22029.1 - 4.3e-08 32.9 9.9 4.3e-08 32.9 9.9 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22029.1 - 2.3e-07 30.7 7.6 2.3e-07 30.7 7.6 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22029.1 - 2.6e-05 24.3 7.9 2.6e-05 24.3 7.9 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22029.1 - 0.00017 21.5 8.6 0.00017 21.5 8.6 4.2 4 1 1 5 5 4 1 zinc-RING finger domain Phasin PF05597.11 PVD22029.1 - 0.0028 17.6 1.2 0.018 15.1 1.2 2.1 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Laminin_II PF06009.12 PVD22029.1 - 0.01 15.8 3.6 0.019 15.0 3.6 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF1465 PF07323.12 PVD22029.1 - 0.016 15.0 1.7 0.3 10.9 0.5 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1465) DUF1664 PF07889.12 PVD22029.1 - 0.018 15.1 8.0 0.054 13.5 5.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 PVD22029.1 - 0.023 15.2 2.6 0.044 14.3 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RmuC PF02646.16 PVD22029.1 - 0.029 13.5 1.2 0.082 12.0 0.5 1.8 1 1 1 2 2 2 0 RmuC family Fibin PF15819.5 PVD22029.1 - 0.039 13.7 1.4 0.087 12.6 1.4 1.5 1 0 0 1 1 1 0 Fin bud initiation factor homologue HsbA PF12296.8 PVD22029.1 - 0.04 14.3 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Golgin_A5 PF09787.9 PVD22029.1 - 0.049 13.1 3.6 0.081 12.4 3.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 PVD22029.1 - 0.056 12.7 0.4 0.085 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ArfGap PF01412.18 PVD22029.1 - 0.074 13.1 28.3 0.17 12.0 8.8 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf COG2 PF06148.11 PVD22029.1 - 0.079 13.0 6.0 0.12 12.5 4.4 2.1 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 PVD22029.1 - 0.098 12.3 9.4 0.53 9.9 9.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 PVD22029.1 - 0.1 12.6 3.4 0.61 10.1 1.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 PVD22029.1 - 0.24 11.9 7.0 1.3 9.5 2.4 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.6 PVD22029.1 - 0.25 11.8 3.7 0.45 10.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-HIT PF04438.16 PVD22029.1 - 0.25 11.2 18.1 0.053 13.4 6.2 4.0 3 0 0 3 3 3 0 HIT zinc finger TMPIT PF07851.13 PVD22029.1 - 0.41 9.9 2.9 0.62 9.3 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.6 PVD22029.1 - 0.72 10.3 5.2 1.4 9.4 4.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Spc24 PF08286.11 PVD22029.1 - 2.1 8.6 4.5 5.6 7.3 4.4 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 PVD22029.1 - 6.5 7.2 8.6 3.1 8.2 5.2 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) zf-C3HC4 PF00097.25 PVD22030.1 - 6.6e-10 38.7 6.3 6.6e-10 38.7 6.3 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22030.1 - 2.9e-09 36.7 9.5 2.9e-09 36.7 9.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22030.1 - 3.8e-09 36.7 7.8 3.8e-09 36.7 7.8 3.4 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22030.1 - 2.9e-08 33.5 9.7 2.9e-08 33.5 9.7 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22030.1 - 4.4e-07 29.8 7.3 4.4e-07 29.8 7.3 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22030.1 - 5.4e-07 29.3 8.0 5.4e-07 29.3 8.0 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22030.1 - 6e-05 22.9 8.1 6e-05 22.9 8.1 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22030.1 - 7.5e-05 22.8 7.9 7.5e-05 22.8 7.9 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22030.1 - 0.023 14.9 8.1 0.023 14.9 8.1 4.1 4 1 0 4 4 4 0 B-box zinc finger Phasin PF05597.11 PVD22030.1 - 0.056 13.5 0.6 0.098 12.7 0.6 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BfiI_DBD PF18243.1 PVD22030.1 - 0.14 11.8 0.0 0.84 9.2 0.0 1.9 1 1 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain zf-C3HC4 PF00097.25 PVD22031.1 - 4.5e-10 39.2 8.1 4.5e-10 39.2 8.1 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22031.1 - 1.3e-09 38.1 36.1 2.1e-05 24.6 5.4 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22031.1 - 9.7e-09 35.0 39.7 1.1e-08 34.8 9.7 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22031.1 - 1.2e-08 35.1 8.9 1.2e-08 35.1 8.9 3.5 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22031.1 - 1.3e-07 31.3 10.8 1.3e-07 31.3 10.8 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22031.1 - 2.5e-07 30.6 7.7 2.5e-07 30.6 7.7 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22031.1 - 2e-06 27.5 8.8 2e-06 27.5 8.8 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22031.1 - 2.9e-05 24.1 8.0 2.9e-05 24.1 8.0 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22031.1 - 0.00059 19.7 10.1 0.00059 19.7 10.1 4.1 3 1 1 4 4 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22031.1 - 0.024 14.7 28.6 0.043 13.9 7.6 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Baculo_PEP_C PF04513.12 PVD22031.1 - 0.034 14.2 4.7 0.037 14.1 2.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.11 PVD22031.1 - 0.037 13.6 3.2 0.061 12.8 3.2 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.12 PVD22031.1 - 0.061 13.4 3.6 0.062 13.4 1.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3829 PF12889.7 PVD22031.1 - 0.073 12.5 0.6 0.24 10.8 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Phasin PF05597.11 PVD22031.1 - 0.077 13.0 5.9 0.065 13.2 2.6 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlaF PF07309.11 PVD22031.1 - 0.13 12.2 0.7 0.28 11.2 0.7 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF V_ATPase_I PF01496.19 PVD22031.1 - 0.53 8.1 4.7 0.99 7.2 0.8 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FAM167 PF11652.8 PVD22031.1 - 2.2 8.8 6.4 1.1 9.8 1.1 2.8 2 1 1 3 3 3 0 FAM167 DUF1664 PF07889.12 PVD22031.1 - 3.5 7.7 10.5 7.4 6.6 3.7 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.6 PVD22032.1 - 2.5e-08 33.6 13.2 2.5e-08 33.6 13.2 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22032.1 - 5.2e-08 32.6 9.6 5.2e-08 32.6 9.6 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22032.1 - 5.7e-07 29.3 13.2 5.7e-07 29.3 13.2 3.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22032.1 - 1.1e-06 28.8 10.1 1.1e-06 28.8 10.1 3.7 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22032.1 - 4.2e-06 26.7 10.3 4.2e-06 26.7 10.3 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22032.1 - 3.5e-05 23.7 11.9 3.5e-05 23.7 11.9 3.9 3 1 1 4 4 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22032.1 - 5.2e-05 23.3 11.0 5.2e-05 23.3 11.0 3.6 5 1 0 5 5 1 1 zinc finger of C3HC4-type, RING TPR_MLP1_2 PF07926.12 PVD22032.1 - 0.0045 17.1 3.4 0.0089 16.1 3.4 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein zf-B_box PF00643.24 PVD22032.1 - 0.005 17.0 8.5 0.005 17.0 8.5 4.0 4 1 0 4 4 3 2 B-box zinc finger Laminin_II PF06009.12 PVD22032.1 - 0.016 15.2 3.0 0.034 14.2 3.0 1.5 1 0 0 1 1 1 0 Laminin Domain II Exonuc_VII_L PF02601.15 PVD22032.1 - 0.021 14.4 0.5 0.025 14.1 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 PVD22032.1 - 0.055 13.5 2.5 0.12 12.3 2.5 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) P22_Tail-4 PF11650.8 PVD22032.1 - 0.078 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 P22 tail accessory factor DUF3450 PF11932.8 PVD22032.1 - 0.08 12.2 3.8 0.12 11.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 PVD22032.1 - 0.093 12.8 7.8 0.41 10.7 4.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 PVD22032.1 - 0.11 11.4 1.8 0.15 10.9 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 PVD22032.1 - 0.12 12.5 3.8 0.24 11.4 3.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.8 PVD22032.1 - 0.14 10.9 0.8 0.17 10.7 0.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FH2 PF02181.23 PVD22032.1 - 0.17 11.0 3.9 0.47 9.5 4.0 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF1465 PF07323.12 PVD22032.1 - 0.24 11.2 3.7 1 9.2 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1465) V_ATPase_I PF01496.19 PVD22032.1 - 0.28 9.0 0.9 0.42 8.5 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 PVD22032.1 - 0.63 9.2 2.6 0.91 8.7 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Plasmid_RAQPRD PF09686.10 PVD22032.1 - 1.1 9.5 4.9 1.5 9.1 0.7 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) COG2 PF06148.11 PVD22032.1 - 1.2 9.2 6.3 10 6.2 1.1 2.6 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C3HC4 PF00097.25 PVD22033.1 - 2.2e-10 40.2 6.2 2.2e-10 40.2 6.2 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22033.1 - 1.5e-09 37.6 9.7 1.5e-09 37.6 9.7 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22033.1 - 2.3e-09 37.4 7.8 2.3e-09 37.4 7.8 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22033.1 - 1.8e-08 34.3 5.9 1.8e-08 34.3 5.9 2.6 2 1 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22033.1 - 2e-08 34.0 9.5 2e-08 34.0 9.5 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22033.1 - 3.2e-08 33.6 32.4 0.00026 21.1 9.9 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22033.1 - 2.8e-07 30.3 7.7 2.8e-07 30.3 7.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22033.1 - 6.9e-06 26.1 6.7 6.9e-06 26.1 6.7 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22033.1 - 0.00011 22.1 8.7 0.00011 22.1 8.7 3.5 3 1 1 4 4 3 1 zinc-RING finger domain DUF1664 PF07889.12 PVD22033.1 - 0.033 14.2 14.3 0.81 9.7 2.5 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PVD22033.1 - 0.056 13.5 6.4 0.074 13.1 3.0 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.11 PVD22033.1 - 0.057 12.9 3.8 0.1 12.1 3.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein YlbD_coat PF14071.6 PVD22033.1 - 0.069 13.4 0.8 0.14 12.4 0.8 1.5 1 0 0 1 1 1 0 Putative coat protein DUF3829 PF12889.7 PVD22033.1 - 0.13 11.8 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Phasin PF05597.11 PVD22033.1 - 0.26 11.3 3.8 0.19 11.7 0.9 2.3 3 0 0 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FH2 PF02181.23 PVD22033.1 - 0.4 9.7 7.2 0.2 10.7 4.7 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain ArfGap PF01412.18 PVD22033.1 - 0.55 10.3 28.5 0.15 12.1 9.2 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Spc7 PF08317.11 PVD22033.1 - 0.69 8.7 8.1 0.43 9.4 6.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 PVD22033.1 - 0.8 9.7 5.0 0.67 10.0 1.8 2.3 2 1 0 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.18 PVD22033.1 - 1.5 8.6 9.0 0.48 10.3 5.4 1.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FAM167 PF11652.8 PVD22033.1 - 4.2 7.9 9.4 0.46 11.0 0.8 3.1 2 1 1 3 3 3 0 FAM167 zf-B_box PF00643.24 PVD22034.1 - 5.6e-16 58.4 49.8 2.4e-05 24.4 6.1 5.9 5 0 0 5 5 5 3 B-box zinc finger zf-C3HC4 PF00097.25 PVD22034.1 - 1.1e-07 31.6 10.3 1.1e-07 31.6 10.3 4.4 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22034.1 - 1.9e-07 30.8 13.1 1.9e-07 30.8 13.1 4.9 5 0 0 5 5 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22034.1 - 4.6e-07 30.1 11.4 4.6e-07 30.1 11.4 4.4 4 0 0 4 4 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22034.1 - 2.2e-06 27.4 13.1 2.2e-06 27.4 13.1 4.9 5 0 0 5 5 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22034.1 - 3.6e-06 26.9 9.9 3.6e-06 26.9 9.9 2.8 2 1 0 2 2 1 1 RING-type zinc-finger TelA PF05816.11 PVD22034.1 - 7e-06 25.3 6.6 0.021 13.9 0.2 2.2 2 0 0 2 2 2 2 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 PVD22034.1 - 1.9e-05 24.6 10.6 0.0059 16.5 4.5 2.6 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Dynamin_M PF01031.20 PVD22034.1 - 4.9e-05 22.7 5.7 0.01 15.1 1.4 2.4 2 0 0 2 2 2 2 Dynamin central region DUF3829 PF12889.7 PVD22034.1 - 7.3e-05 22.4 4.5 0.0082 15.7 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3829) Med21 PF11221.8 PVD22034.1 - 0.00033 20.9 2.6 0.05 13.9 0.5 2.6 2 0 0 2 2 2 1 Subunit 21 of Mediator complex Baculo_PEP_C PF04513.12 PVD22034.1 - 0.00074 19.6 14.7 0.037 14.1 0.8 4.2 2 2 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_4 PF15227.6 PVD22034.1 - 0.00096 19.3 11.2 0.00096 19.3 11.2 3.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING TPR_MLP1_2 PF07926.12 PVD22034.1 - 0.0011 19.1 11.6 0.083 12.9 2.0 3.0 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF5601 PF18151.1 PVD22034.1 - 0.0025 18.1 0.6 3.9 7.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) DUF3450 PF11932.8 PVD22034.1 - 0.0026 17.1 7.2 0.19 11.0 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) Phasin PF05597.11 PVD22034.1 - 0.0031 17.5 12.4 0.27 11.2 0.5 3.6 3 1 1 4 4 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-RING_5 PF14634.6 PVD22034.1 - 0.0042 17.0 12.4 0.0042 17.0 12.4 5.3 5 1 0 5 5 2 1 zinc-RING finger domain EzrA PF06160.12 PVD22034.1 - 0.0074 14.5 5.7 0.11 10.6 2.0 2.2 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 PVD22034.1 - 0.01 15.4 10.4 0.11 12.1 2.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 PVD22034.1 - 0.012 15.2 15.2 0.027 13.9 3.6 2.3 2 1 0 2 2 2 0 Golgin subfamily A member 5 ArfGap PF01412.18 PVD22034.1 - 0.014 15.5 8.5 0.014 15.5 8.5 5.6 3 2 2 5 5 5 0 Putative GTPase activating protein for Arf Laminin_II PF06009.12 PVD22034.1 - 0.021 14.8 11.3 0.058 13.4 0.6 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PVD22034.1 - 0.026 14.6 23.8 0.74 9.9 4.3 5.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) RecC_C PF17946.1 PVD22034.1 - 0.028 14.2 0.8 0.37 10.5 0.2 2.5 2 2 0 2 2 2 0 RecC C-terminal domain PRAS PF15798.5 PVD22034.1 - 0.028 15.0 0.2 5.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 IFT57 PF10498.9 PVD22034.1 - 0.054 12.5 15.3 0.26 10.2 5.1 2.8 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 SHE3 PF17078.5 PVD22034.1 - 0.067 12.9 9.8 0.66 9.7 1.8 2.6 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1465 PF07323.12 PVD22034.1 - 0.089 12.6 9.9 1.2 9.0 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1465) RmuC PF02646.16 PVD22034.1 - 0.11 11.6 8.9 1.9 7.6 0.2 3.3 2 2 1 3 3 3 0 RmuC family BfiI_DBD PF18243.1 PVD22034.1 - 0.11 12.0 0.1 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Metal-independent restriction enzyme BfiI DNA binding domain DivIVA PF05103.13 PVD22034.1 - 0.14 12.3 9.2 3.2 7.8 3.8 2.7 2 0 0 2 2 2 0 DivIVA protein Med30 PF11315.8 PVD22034.1 - 0.14 12.4 8.5 0.25 11.5 0.2 3.3 2 1 0 3 3 3 0 Mediator complex subunit 30 DUF745 PF05335.13 PVD22034.1 - 0.14 11.9 8.1 2.8 7.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) YlbD_coat PF14071.6 PVD22034.1 - 0.15 12.4 8.4 1.1 9.5 2.6 2.5 2 0 0 2 2 2 0 Putative coat protein Spc7 PF08317.11 PVD22034.1 - 0.19 10.5 14.2 0.24 10.3 5.8 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein BRCA-2_OB3 PF09104.10 PVD22034.1 - 0.33 10.6 2.3 19 4.9 0.3 2.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 HrpB7 PF09486.10 PVD22034.1 - 0.34 11.3 11.0 1 9.7 1.2 4.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) E2F_CC-MB PF16421.5 PVD22034.1 - 0.35 11.2 8.9 5.8 7.4 0.3 3.0 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Allexi_40kDa PF05549.11 PVD22034.1 - 0.36 10.3 12.4 2.3 7.6 2.9 2.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein YscO-like PF16789.5 PVD22034.1 - 0.46 10.5 8.9 0.34 10.9 2.5 2.7 2 0 0 2 2 2 0 YscO-like protein LXG PF04740.12 PVD22034.1 - 0.49 10.1 7.4 1.4 8.5 1.2 2.9 2 1 1 3 3 3 0 LXG domain of WXG superfamily ATP-synt_B PF00430.18 PVD22034.1 - 0.64 10.1 5.9 10 6.2 0.2 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) FAM167 PF11652.8 PVD22034.1 - 0.71 10.4 13.0 0.4 11.2 0.8 4.0 3 2 1 4 4 2 0 FAM167 Bacillus_HBL PF05791.11 PVD22034.1 - 0.81 9.5 6.1 13 5.5 1.7 2.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) LMBR1 PF04791.16 PVD22034.1 - 0.98 8.2 9.6 0.12 11.3 1.9 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 PVD22034.1 - 1.1 9.5 5.5 4.5 7.6 0.3 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain IKKbetaNEMObind PF12179.8 PVD22034.1 - 1.1 9.3 9.1 1.9 8.6 0.5 3.9 3 2 2 5 5 3 0 I-kappa-kinase-beta NEMO binding domain DUF4771 PF15995.5 PVD22034.1 - 1.2 9.4 4.9 6.1 7.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) DUF4200 PF13863.6 PVD22034.1 - 1.2 9.5 8.2 1.9 8.9 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CLZ PF16526.5 PVD22034.1 - 1.3 9.5 16.3 3.8 7.9 0.3 5.4 3 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaF PF07309.11 PVD22034.1 - 1.4 8.9 4.1 2.6 8.1 1.0 2.5 2 0 0 2 2 2 0 Flagellar protein FlaF TMPIT PF07851.13 PVD22034.1 - 1.8 7.8 13.5 2.1 7.5 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein LMP PF04778.12 PVD22034.1 - 1.9 8.4 13.3 1.5 8.7 6.2 2.8 2 1 0 2 2 2 0 LMP repeated region Cor1 PF04803.12 PVD22034.1 - 1.9 8.7 18.9 0.69 10.1 1.9 2.9 3 0 0 3 3 2 0 Cor1/Xlr/Xmr conserved region ING PF12998.7 PVD22034.1 - 2.6 8.7 11.7 2 9.0 3.5 3.0 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sec20 PF03908.13 PVD22034.1 - 2.9 7.9 6.3 2.7 8.0 1.1 2.9 2 2 0 2 2 2 0 Sec20 DUF3683 PF12447.8 PVD22034.1 - 3.4 7.8 9.8 2.3 8.4 1.1 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF3683) DUF948 PF06103.11 PVD22034.1 - 3.6 7.9 9.0 30 5.0 0.4 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Med4 PF10018.9 PVD22034.1 - 3.7 7.2 11.3 5.5 6.6 2.9 3.0 3 1 0 3 3 2 0 Vitamin-D-receptor interacting Mediator subunit 4 YabA PF06156.13 PVD22034.1 - 3.8 8.2 10.7 11 6.7 3.5 2.9 2 0 0 2 2 2 0 Initiation control protein YabA Syntaxin-6_N PF09177.11 PVD22034.1 - 7 7.3 13.9 44 4.7 1.2 4.2 2 2 1 3 3 3 0 Syntaxin 6, N-terminal zf-C3HC4_3 PF13920.6 PVD22035.1 - 5.7e-17 61.3 59.7 9.2e-09 35.0 9.4 4.4 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22035.1 - 1.4e-16 60.1 20.3 1.6e-09 37.4 6.4 4.3 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22035.1 - 6.2e-16 58.5 23.2 5e-09 36.4 7.8 4.8 5 0 0 5 5 4 2 Ring finger domain Prok-RING_4 PF14447.6 PVD22035.1 - 1.5e-13 50.3 27.8 4.6e-08 32.8 9.8 4.5 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22035.1 - 7.2e-12 45.1 25.2 8.7e-08 32.1 5.9 3.6 3 1 0 3 3 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22035.1 - 2.9e-11 43.0 24.0 7.3e-07 28.9 8.2 4.8 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) Neuralized PF07177.12 PVD22035.1 - 1.6e-08 34.7 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Neuralized zf-C3HC4_4 PF15227.6 PVD22035.1 - 6.4e-08 32.6 23.2 4.7e-05 23.5 7.5 3.9 4 0 0 4 4 3 2 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22035.1 - 1.9e-07 31.1 45.0 9.2e-05 22.5 5.6 5.1 5 1 0 5 5 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD22035.1 - 4.7e-07 29.7 24.3 9.4e-05 22.3 8.0 4.7 4 1 1 5 5 3 2 zinc-RING finger domain ArfGap PF01412.18 PVD22035.1 - 0.0076 16.3 8.3 0.0076 16.3 8.3 4.4 3 1 1 4 4 4 2 Putative GTPase activating protein for Arf PPP4R2 PF09184.11 PVD22035.1 - 0.031 13.9 10.0 0.05 13.2 10.0 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 PVD22035.1 - 0.038 13.3 9.0 0.053 12.9 9.0 1.1 1 0 0 1 1 1 0 BUD22 DUF3552 PF12072.8 PVD22035.1 - 0.2 11.1 5.9 0.3 10.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FH2 PF02181.23 PVD22035.1 - 0.21 10.7 4.0 0.31 10.1 4.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain 5_nucleotid PF05761.14 PVD22035.1 - 0.28 10.0 1.8 0.44 9.4 1.8 1.2 1 0 0 1 1 1 0 5' nucleotidase family TBCA PF02970.16 PVD22035.1 - 0.33 11.3 7.1 0.77 10.1 7.1 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF2457 PF10446.9 PVD22035.1 - 0.35 10.0 27.4 0.6 9.2 27.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 PVD22035.1 - 0.51 8.3 2.8 0.89 7.6 2.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Baculo_PEP_C PF04513.12 PVD22035.1 - 0.67 10.0 4.8 2.9 7.9 3.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus THOC7 PF05615.13 PVD22035.1 - 0.71 10.2 6.2 1.9 8.8 5.6 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 TFIIA PF03153.13 PVD22035.1 - 1.4 8.9 16.4 1.9 8.4 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 PVD22035.1 - 2.8 7.3 16.3 5.3 6.4 16.3 1.4 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 PVD22035.1 - 2.9 5.9 27.3 0.033 12.3 18.5 1.9 2 0 0 2 2 2 0 DNA polymerase phi DUF1664 PF07889.12 PVD22035.1 - 4.9 7.2 7.6 37 4.4 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-B_dimeris PF09026.10 PVD22035.1 - 5.7 7.4 31.0 16 5.9 31.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3HC4 PF00097.25 PVD22036.1 - 3.6e-10 39.5 6.6 3.6e-10 39.5 6.6 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22036.1 - 8.9e-09 35.4 16.8 8.9e-06 25.8 5.0 4.1 4 1 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD22036.1 - 2.8e-08 34.0 7.8 2.8e-08 34.0 7.8 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22036.1 - 3.8e-08 33.1 9.9 3.8e-08 33.1 9.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22036.1 - 1.2e-07 31.5 10.4 1.2e-07 31.5 10.4 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22036.1 - 3.3e-07 30.0 8.1 3.3e-07 30.0 8.1 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22036.1 - 1.3e-06 28.3 11.2 1.3e-06 28.3 11.2 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22036.1 - 4.8e-06 26.6 7.5 4.8e-06 26.6 7.5 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING 5_nucleotid PF05761.14 PVD22036.1 - 0.00059 18.9 1.1 0.00059 18.9 1.1 2.1 2 0 0 2 2 2 1 5' nucleotidase family zf-RING_5 PF14634.6 PVD22036.1 - 0.00083 19.3 9.2 0.00083 19.3 9.2 4.4 3 1 1 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22036.1 - 0.61 10.2 33.2 0.081 13.0 4.2 4.5 3 1 1 4 4 4 0 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 PVD22036.1 - 1.4 9.0 14.7 4.2 7.5 14.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 PVD22036.1 - 2.1 7.1 6.8 3.3 6.4 6.8 1.2 1 0 0 1 1 1 0 Androgen receptor OmpH PF03938.14 PVD22036.1 - 4.2 7.7 19.1 0.62 10.4 8.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 PVD22036.1 - 4.9 7.2 9.2 0.45 10.5 0.2 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4446 PF14584.6 PVD22036.1 - 9.3 6.2 8.3 4.5 7.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) zf-C3HC4 PF00097.25 PVD22037.1 - 4e-10 39.4 6.6 4e-10 39.4 6.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22037.1 - 2.4e-09 36.9 9.7 2.4e-09 36.9 9.7 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22037.1 - 2.7e-09 37.2 7.8 2.7e-09 37.2 7.8 3.4 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22037.1 - 7.2e-09 35.4 9.8 7.2e-09 35.4 9.8 3.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22037.1 - 3e-08 33.5 6.4 3e-08 33.5 6.4 2.8 3 1 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD22037.1 - 4.3e-08 33.2 35.2 2.7e-05 24.2 9.3 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22037.1 - 5.3e-08 32.6 8.3 5.3e-08 32.6 8.3 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22037.1 - 2.5e-05 24.3 8.0 2.5e-05 24.3 8.0 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22037.1 - 3.5e-05 23.7 8.0 3.5e-05 23.7 8.0 3.6 3 1 1 4 4 2 1 zinc-RING finger domain DUF3829 PF12889.7 PVD22037.1 - 0.009 15.5 0.3 0.014 14.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) ArfGap PF01412.18 PVD22037.1 - 0.015 15.3 7.9 0.015 15.3 7.9 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Phasin PF05597.11 PVD22037.1 - 0.075 13.0 4.2 0.12 12.4 1.6 2.5 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 PVD22037.1 - 0.17 11.7 5.6 0.14 12.1 3.5 1.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD22037.1 - 0.53 10.3 4.4 0.99 9.4 2.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_lipo_1 PF05714.11 PVD22037.1 - 0.53 10.0 3.3 12 5.6 0.5 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF1664 PF07889.12 PVD22037.1 - 1.1 9.3 8.9 1.5 8.9 3.8 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.25 PVD22038.1 - 1e-09 38.1 7.8 1e-09 38.1 7.8 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22038.1 - 4.4e-09 36.5 8.9 4.4e-09 36.5 8.9 3.7 4 0 0 4 4 3 1 Ring finger domain zf-B_box PF00643.24 PVD22038.1 - 1.9e-08 34.3 34.6 3e-05 24.1 6.0 3.9 3 1 0 3 3 3 2 B-box zinc finger Neuralized PF07177.12 PVD22038.1 - 2.3e-08 34.2 0.0 4.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Neuralized zf-C3HC4_3 PF13920.6 PVD22038.1 - 3.2e-08 33.3 39.8 4.2e-08 32.9 9.7 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22038.1 - 3.4e-07 30.2 6.9 3.4e-07 30.2 6.9 2.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22038.1 - 1.3e-06 28.2 8.6 1.3e-06 28.2 8.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22038.1 - 3.5e-06 26.8 11.0 3.5e-06 26.8 11.0 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22038.1 - 3.6e-05 23.8 7.9 3.6e-05 23.8 7.9 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22038.1 - 0.0025 17.7 10.0 0.0025 17.7 10.0 4.0 3 1 1 4 4 4 1 zinc-RING finger domain DUF3829 PF12889.7 PVD22038.1 - 0.012 15.1 0.6 0.021 14.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) TelA PF05816.11 PVD22038.1 - 0.02 14.0 2.0 0.033 13.3 2.0 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Baculo_PEP_C PF04513.12 PVD22038.1 - 0.028 14.5 2.8 0.066 13.3 2.8 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlbD_coat PF14071.6 PVD22038.1 - 0.066 13.5 2.0 0.15 12.3 2.0 1.5 1 0 0 1 1 1 0 Putative coat protein NADH-UOR_E PF16514.5 PVD22038.1 - 0.18 12.1 1.7 3.8 7.9 0.6 2.5 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E Phasin PF05597.11 PVD22038.1 - 0.35 10.9 8.4 0.053 13.5 2.4 2.6 3 1 1 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Muted PF14942.6 PVD22038.1 - 0.51 10.7 7.3 1 9.7 7.3 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein COG2 PF06148.11 PVD22038.1 - 0.64 10.1 5.3 3.7 7.7 3.5 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ArfGap PF01412.18 PVD22038.1 - 1 9.5 30.7 0.029 14.4 9.1 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf FAM167 PF11652.8 PVD22038.1 - 1.2 9.7 9.5 0.39 11.2 0.5 3.4 2 1 1 3 3 3 0 FAM167 OGFr_N PF04664.13 PVD22039.1 - 2.2e-70 236.4 4.9 5.4e-70 235.2 4.9 1.6 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region zf-C3HC4 PF00097.25 PVD22039.1 - 1.1e-09 38.0 6.2 1.1e-09 38.0 6.2 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22039.1 - 5.2e-09 35.8 8.9 5.2e-09 35.8 8.9 4.3 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22039.1 - 7.9e-09 35.7 7.3 7.9e-09 35.7 7.3 4.4 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22039.1 - 5.5e-08 32.5 9.0 5.5e-08 32.5 9.0 4.0 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22039.1 - 3.3e-07 30.0 7.9 3.3e-07 30.0 7.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22039.1 - 1.7e-06 27.9 10.2 1.7e-06 27.9 10.2 3.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22039.1 - 2.5e-05 24.3 6.7 2.5e-05 24.3 6.7 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22039.1 - 0.00011 22.0 8.6 0.00011 22.0 8.6 4.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-B_box PF00643.24 PVD22039.1 - 0.00047 20.2 23.8 0.0011 19.0 9.1 4.9 5 0 0 5 5 5 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22040.1 - 3e-10 39.8 7.6 3e-10 39.8 7.6 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22040.1 - 2.7e-09 36.8 10.4 2.7e-09 36.8 10.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22040.1 - 6.4e-09 35.7 5.5 6.4e-09 35.7 5.5 3.0 2 2 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD22040.1 - 7.8e-09 35.7 8.3 7.8e-09 35.7 8.3 3.7 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22040.1 - 2.2e-08 33.8 10.3 2.2e-08 33.8 10.3 3.4 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22040.1 - 5.7e-08 32.5 8.4 5.7e-08 32.5 8.4 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22040.1 - 4.2e-06 26.8 8.2 4.2e-06 26.8 8.2 4.0 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22040.1 - 3.4e-05 23.7 9.3 3.4e-05 23.7 9.3 3.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.24 PVD22040.1 - 5e-05 23.4 3.4 5e-05 23.4 3.4 4.3 4 1 0 4 4 3 2 B-box zinc finger ArfGap PF01412.18 PVD22040.1 - 0.0025 17.9 33.8 0.073 13.1 3.5 3.4 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf TPR_MLP1_2 PF07926.12 PVD22040.1 - 0.3 11.2 6.3 2.9 8.0 1.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 PVD22040.1 - 2 8.7 7.7 1 9.6 5.5 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-C3HC4 PF00097.25 PVD22041.1 - 2.4e-10 40.1 6.7 2.4e-10 40.1 6.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22041.1 - 1.9e-09 37.2 9.5 1.9e-09 37.2 9.5 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22041.1 - 2e-09 37.6 8.0 2e-09 37.6 8.0 3.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22041.1 - 8.5e-09 35.3 6.6 8.5e-09 35.3 6.6 2.9 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22041.1 - 8.6e-09 35.1 9.8 8.6e-09 35.1 9.8 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22041.1 - 4e-08 33.3 34.4 3.1e-05 24.0 4.9 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22041.1 - 9.1e-08 31.8 8.3 9.1e-08 31.8 8.3 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22041.1 - 3.1e-05 23.8 8.5 3.1e-05 23.8 8.5 3.8 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22041.1 - 3.9e-05 23.7 8.2 3.9e-05 23.7 8.2 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3829 PF12889.7 PVD22041.1 - 0.025 14.1 0.7 0.036 13.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) zf-rbx1 PF12678.7 PVD22041.1 - 0.031 14.5 20.4 0.054 13.8 6.1 3.9 3 0 0 3 3 3 0 RING-H2 zinc finger domain LMP PF04778.12 PVD22041.1 - 0.05 13.5 3.3 0.096 12.6 3.3 1.4 1 0 0 1 1 1 0 LMP repeated region FAM167 PF11652.8 PVD22041.1 - 0.11 13.0 0.6 0.11 13.0 0.6 2.4 2 1 0 2 2 2 0 FAM167 FIN1 PF17300.2 PVD22041.1 - 0.12 11.9 8.1 3.2 7.2 3.9 2.4 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 YlbD_coat PF14071.6 PVD22041.1 - 0.24 11.7 1.3 0.45 10.8 1.3 1.6 1 0 0 1 1 1 0 Putative coat protein Baculo_PEP_C PF04513.12 PVD22041.1 - 0.27 11.3 5.3 0.94 9.5 4.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.7 PVD22041.1 - 0.37 11.4 4.0 0.31 11.7 1.4 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PspA_IM30 PF04012.12 PVD22041.1 - 0.48 10.0 6.1 0.32 10.5 4.0 1.7 1 1 0 1 1 1 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 PVD22041.1 - 0.78 9.8 7.9 0.056 13.5 2.7 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ArfGap PF01412.18 PVD22041.1 - 0.87 9.7 33.1 0.083 13.0 8.4 4.0 3 1 2 5 5 5 0 Putative GTPase activating protein for Arf DUF1664 PF07889.12 PVD22041.1 - 1.2 9.2 9.3 0.8 9.8 4.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 PVD22041.1 - 2.8 8.0 7.2 6.8 6.8 2.2 3.0 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C3HC4_3 PF13920.6 PVD22042.1 - 8.6e-10 38.3 37.2 5.6e-09 35.7 9.6 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22042.1 - 9.2e-10 38.2 6.4 9.2e-10 38.2 6.4 3.6 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22042.1 - 2.8e-09 37.2 7.8 2.8e-09 37.2 7.8 4.2 4 0 0 4 4 4 1 Ring finger domain zf-B_box PF00643.24 PVD22042.1 - 3.2e-09 36.8 36.3 1.9e-05 24.7 3.7 4.5 4 1 0 4 4 4 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22042.1 - 2.3e-08 33.8 9.9 2.3e-08 33.8 9.9 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22042.1 - 5.7e-08 32.7 6.7 5.7e-08 32.7 6.7 2.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22042.1 - 4.1e-07 29.7 8.2 4.1e-07 29.7 8.2 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22042.1 - 2.7e-05 24.2 7.7 2.7e-05 24.2 7.7 3.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22042.1 - 8.6e-05 22.4 8.3 8.6e-05 22.4 8.3 4.5 4 2 1 5 5 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22042.1 - 0.0027 17.8 28.2 0.015 15.4 7.8 3.5 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf Phasin PF05597.11 PVD22042.1 - 0.0031 17.5 1.2 0.008 16.2 1.2 1.7 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PVD22042.1 - 0.027 14.5 1.9 0.13 12.3 0.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 PVD22042.1 - 0.036 14.2 3.7 0.084 13.0 2.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nsp1_C PF05064.13 PVD22042.1 - 0.038 13.8 0.2 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF1465 PF07323.12 PVD22042.1 - 0.045 13.6 0.5 1.7 8.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) V_ATPase_I PF01496.19 PVD22042.1 - 0.054 11.4 3.1 0.095 10.6 2.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 PVD22042.1 - 0.17 11.9 7.6 0.79 9.8 4.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 PVD22042.1 - 0.25 11.9 3.7 0.11 13.1 1.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) DUF1319 PF07028.11 PVD22042.1 - 0.45 10.8 3.5 1 9.6 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) DUF2746 PF10874.8 PVD22042.1 - 0.75 10.3 4.4 13 6.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) zf-C3HC4 PF00097.25 PVD22043.1 - 9.3e-10 38.2 6.4 9.3e-10 38.2 6.4 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22043.1 - 1.1e-09 38.2 32.3 5.1e-05 23.3 9.4 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD22043.1 - 2.8e-09 37.2 7.8 2.8e-09 37.2 7.8 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22043.1 - 3.6e-09 36.3 37.8 5.1e-09 35.9 9.4 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22043.1 - 2.6e-08 33.6 9.8 2.6e-08 33.6 9.8 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22043.1 - 4.6e-08 33.0 6.4 4.6e-08 33.0 6.4 3.1 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22043.1 - 4.2e-07 29.7 8.2 4.2e-07 29.7 8.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22043.1 - 2.8e-05 24.2 7.7 2.8e-05 24.2 7.7 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22043.1 - 8.7e-05 22.4 8.3 8.7e-05 22.4 8.3 4.1 3 2 1 4 4 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22043.1 - 0.0023 18.0 28.8 0.0045 17.1 8.4 3.6 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf V_ATPase_I PF01496.19 PVD22043.1 - 0.039 11.9 3.2 0.056 11.4 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 PVD22043.1 - 0.13 12.3 9.7 1.1 9.2 3.5 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PVD22043.1 - 0.24 11.4 5.9 0.65 10.0 2.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 PVD22043.1 - 0.28 11.2 5.0 0.34 10.9 3.2 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-HIT PF04438.16 PVD22043.1 - 0.36 10.7 18.7 0.052 13.4 6.2 3.7 3 0 0 3 3 3 0 HIT zinc finger COG2 PF06148.11 PVD22043.1 - 3.3 7.8 7.9 2.1 8.5 3.8 2.5 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C3HC4 PF00097.25 PVD22044.1 - 1.4e-09 37.7 6.8 1.4e-09 37.7 6.8 3.8 4 1 0 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22044.1 - 2.5e-09 36.9 39.4 1.1e-08 34.8 9.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22044.1 - 5e-09 36.4 7.9 5e-09 36.4 7.9 4.1 4 0 0 4 4 4 1 Ring finger domain zf-B_box PF00643.24 PVD22044.1 - 6.6e-09 35.8 33.8 1.4e-05 25.1 4.3 4.3 3 1 0 3 3 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22044.1 - 3.4e-08 33.2 10.2 3.4e-08 33.2 10.2 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22044.1 - 8.6e-08 32.1 6.6 8.6e-08 32.1 6.6 2.9 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22044.1 - 8.4e-07 28.7 8.7 8.4e-07 28.7 8.7 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22044.1 - 4.8e-06 26.6 7.8 4.8e-06 26.6 7.8 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22044.1 - 7e-05 22.7 8.9 7e-05 22.7 8.9 4.4 4 1 1 5 5 5 1 zinc-RING finger domain DUF1664 PF07889.12 PVD22044.1 - 0.00081 19.4 10.2 0.047 13.7 5.8 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 PVD22044.1 - 0.01 15.9 3.4 0.021 14.8 3.4 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF1465 PF07323.12 PVD22044.1 - 0.014 15.2 1.5 0.43 10.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Phasin PF05597.11 PVD22044.1 - 0.021 14.8 3.8 0.051 13.6 3.2 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PVD22044.1 - 0.022 14.8 4.2 0.42 10.7 2.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 PVD22044.1 - 0.036 14.5 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A AAA_32 PF13654.6 PVD22044.1 - 0.073 11.8 1.2 0.1 11.4 1.2 1.1 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 PVD22044.1 - 0.1 12.0 7.1 0.017 14.6 3.0 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4200 PF13863.6 PVD22044.1 - 0.13 12.6 4.7 0.27 11.6 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) YlbD_coat PF14071.6 PVD22044.1 - 0.22 11.8 2.6 0.52 10.6 2.6 1.6 1 0 0 1 1 1 0 Putative coat protein MitMem_reg PF13012.6 PVD22044.1 - 0.27 11.6 2.4 0.64 10.5 1.6 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Cor1 PF04803.12 PVD22044.1 - 0.28 11.4 6.6 0.62 10.3 6.6 1.5 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region ArfGap PF01412.18 PVD22044.1 - 0.31 11.1 32.4 0.11 12.6 8.7 3.8 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf COG2 PF06148.11 PVD22044.1 - 0.31 11.1 7.8 0.15 12.1 3.9 2.4 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 PVD22044.1 - 0.57 8.0 4.5 0.82 7.5 4.0 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 PVD22044.1 - 1.5 8.0 4.2 2.6 7.2 4.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Muted PF14942.6 PVD22044.1 - 1.9 8.8 8.9 0.85 10.0 6.2 1.8 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein DUF4665 PF15679.5 PVD22044.1 - 2.8 8.6 7.2 3.8 8.2 2.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) DUF2408 PF10303.9 PVD22044.1 - 5.6 7.5 10.2 4.7 7.8 8.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) CENP-H PF05837.12 PVD22044.1 - 6.2 7.3 11.7 1.6 9.2 5.4 2.7 3 1 0 3 3 2 0 Centromere protein H (CENP-H) CLZ PF16526.5 PVD22044.1 - 7.3 7.0 7.0 3.7 8.0 0.4 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-B_box PF00643.24 PVD22045.1 - 2.1e-10 40.5 36.8 8.2e-06 25.9 8.3 4.2 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22045.1 - 4.5e-10 39.2 6.2 4.5e-10 39.2 6.2 3.6 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22045.1 - 2.1e-09 37.6 7.8 2.1e-09 37.6 7.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22045.1 - 3e-09 36.6 9.5 3e-09 36.6 9.5 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22045.1 - 1.1e-08 34.8 9.8 1.1e-08 34.8 9.8 3.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22045.1 - 1.2e-08 34.8 6.5 1.2e-08 34.8 6.5 2.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22045.1 - 2.5e-07 30.4 8.2 2.5e-07 30.4 8.2 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22045.1 - 2.8e-05 24.2 7.9 2.8e-05 24.2 7.9 3.3 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22045.1 - 3.8e-05 23.6 8.1 3.8e-05 23.6 8.1 4.0 4 1 1 5 5 4 1 zinc-RING finger domain Phasin PF05597.11 PVD22045.1 - 0.0026 17.8 1.9 0.0026 17.8 1.9 2.1 3 0 0 3 3 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 PVD22045.1 - 0.0034 17.4 13.2 0.051 13.6 5.8 2.9 2 1 1 3 3 2 2 Protein of unknown function (DUF1664) TelA PF05816.11 PVD22045.1 - 0.0038 16.4 0.5 0.0064 15.6 0.5 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Laminin_II PF06009.12 PVD22045.1 - 0.004 17.2 3.6 0.0082 16.2 3.6 1.5 1 0 0 1 1 1 1 Laminin Domain II DUF2408 PF10303.9 PVD22045.1 - 0.014 16.0 2.9 0.018 15.6 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1465 PF07323.12 PVD22045.1 - 0.017 15.0 1.2 0.5 10.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) HsbA PF12296.8 PVD22045.1 - 0.021 15.3 0.1 0.049 14.0 0.1 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF3450 PF11932.8 PVD22045.1 - 0.021 14.1 0.5 0.032 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ArfGap PF01412.18 PVD22045.1 - 0.039 14.0 30.3 0.053 13.6 9.2 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf COG2 PF06148.11 PVD22045.1 - 0.07 13.2 6.2 0.12 12.5 3.7 2.5 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cor1 PF04803.12 PVD22045.1 - 0.077 13.2 3.5 0.19 12.0 3.5 1.6 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Baculo_PEP_C PF04513.12 PVD22045.1 - 0.081 13.0 3.8 0.52 10.3 1.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_32 PF13654.6 PVD22045.1 - 0.1 11.3 1.6 0.14 10.9 1.6 1.1 1 0 0 1 1 1 0 AAA domain RmuC PF02646.16 PVD22045.1 - 0.11 11.6 2.4 0.19 10.8 0.6 1.9 1 1 1 2 2 2 0 RmuC family Golgin_A5 PF09787.9 PVD22045.1 - 0.13 11.7 5.8 0.02 14.3 2.2 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc24 PF08286.11 PVD22045.1 - 0.16 12.2 1.6 0.33 11.2 1.6 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2046 PF09755.9 PVD22045.1 - 0.23 10.7 7.7 2.2 7.4 1.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF4200 PF13863.6 PVD22045.1 - 0.42 11.0 4.1 0.79 10.1 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 PVD22045.1 - 1 9.9 9.4 2.6 8.6 2.9 2.8 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 PVD22045.1 - 1.2 8.3 4.1 1.9 7.7 4.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 PVD22045.1 - 1.4 6.8 3.9 1.2 7.0 0.9 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-HIT PF04438.16 PVD22045.1 - 1.6 8.6 21.1 0.051 13.4 6.2 3.9 3 0 0 3 3 3 0 HIT zinc finger CLZ PF16526.5 PVD22045.1 - 3 8.3 5.3 1.5 9.3 0.3 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C3HC4 PF00097.25 PVD22046.1 - 2.6e-09 36.8 10.4 2.6e-09 36.8 10.4 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22046.1 - 3.1e-09 36.8 21.3 7.7e-06 26.0 3.4 4.6 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22046.1 - 2.4e-08 33.7 43.1 2.5e-08 33.6 13.5 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22046.1 - 7.6e-08 32.6 11.8 7.6e-08 32.6 11.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22046.1 - 2.9e-07 30.4 9.3 2.9e-07 30.4 9.3 2.7 2 2 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22046.1 - 3.8e-07 29.8 13.0 3.8e-07 29.8 13.0 3.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22046.1 - 6.1e-06 26.0 11.8 6.1e-06 26.0 11.8 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22046.1 - 9.1e-05 22.5 10.6 9.1e-05 22.5 10.6 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3829 PF12889.7 PVD22046.1 - 0.0034 16.9 1.2 0.0073 15.8 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) TelA PF05816.11 PVD22046.1 - 0.0057 15.8 1.7 0.009 15.1 1.7 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) TPR_MLP1_2 PF07926.12 PVD22046.1 - 0.0096 16.0 3.0 0.02 14.9 3.0 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein zf-RING_5 PF14634.6 PVD22046.1 - 0.014 15.4 12.9 0.014 15.4 12.9 4.0 3 1 1 4 4 4 0 zinc-RING finger domain Nsp1_C PF05064.13 PVD22046.1 - 0.014 15.2 3.7 0.25 11.2 0.4 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region Phasin PF05597.11 PVD22046.1 - 0.017 15.1 3.4 0.036 14.1 2.4 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PVD22046.1 - 0.031 14.3 4.7 0.071 13.1 4.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 PVD22046.1 - 0.032 14.3 7.0 0.12 12.4 2.8 2.9 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ArfGap PF01412.18 PVD22046.1 - 0.032 14.3 27.8 0.082 13.0 7.8 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Apolipoprotein PF01442.18 PVD22046.1 - 0.043 13.7 4.1 0.1 12.5 4.1 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 PVD22046.1 - 0.05 12.5 3.3 0.074 11.9 3.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fibin PF15819.5 PVD22046.1 - 0.056 13.2 2.3 0.11 12.3 2.3 1.4 1 0 0 1 1 1 0 Fin bud initiation factor homologue HsbA PF12296.8 PVD22046.1 - 0.069 13.6 0.7 0.17 12.3 0.7 1.6 1 1 0 1 1 1 0 Hydrophobic surface binding protein A YlbD_coat PF14071.6 PVD22046.1 - 0.13 12.5 1.4 0.25 11.6 1.4 1.5 1 0 0 1 1 1 0 Putative coat protein FAM167 PF11652.8 PVD22046.1 - 0.14 12.7 3.4 0.22 12.0 0.5 2.7 2 1 0 2 2 2 0 FAM167 FH2 PF02181.23 PVD22046.1 - 0.19 10.8 5.6 0.3 10.2 5.6 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF1664 PF07889.12 PVD22046.1 - 0.62 10.1 9.8 2 8.5 6.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Plasmid_RAQPRD PF09686.10 PVD22046.1 - 0.64 10.3 3.0 1.3 9.3 0.2 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TMPIT PF07851.13 PVD22046.1 - 0.67 9.1 3.5 1.1 8.5 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein CLZ PF16526.5 PVD22046.1 - 4.1 7.8 9.1 3.8 7.9 0.1 3.2 3 1 1 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C3HC4 PF00097.25 PVD22047.1 - 1.4e-09 37.7 11.0 1.4e-09 37.7 11.0 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22047.1 - 6.4e-08 32.3 43.9 9.3e-08 31.8 14.5 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22047.1 - 9.9e-08 31.9 9.0 9.9e-08 31.9 9.0 3.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD22047.1 - 3.7e-07 30.4 10.9 3.7e-07 30.4 10.9 3.5 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22047.1 - 4.2e-07 29.7 13.7 4.2e-07 29.7 13.7 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22047.1 - 5e-05 23.4 23.0 8e-05 22.7 9.6 4.2 4 1 0 4 4 3 2 B-box zinc finger zf-RING_5 PF14634.6 PVD22047.1 - 0.00018 21.4 13.7 0.00018 21.4 13.7 3.7 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22047.1 - 0.0012 18.9 11.4 0.0012 18.9 11.4 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING Baculo_PEP_C PF04513.12 PVD22047.1 - 0.0083 16.2 4.2 0.019 15.0 4.2 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Halo_GVPC PF05465.13 PVD22047.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat ArfGap PF01412.18 PVD22047.1 - 0.021 14.9 31.8 0.038 14.1 9.4 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-HIT PF04438.16 PVD22047.1 - 0.023 14.5 6.3 0.023 14.5 6.3 3.4 4 0 0 4 4 3 0 HIT zinc finger Phasin PF05597.11 PVD22047.1 - 0.027 14.5 2.5 0.027 14.5 2.5 2.4 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HsbA PF12296.8 PVD22047.1 - 0.029 14.8 1.2 0.056 13.9 1.2 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A 5_nucleotid PF05761.14 PVD22047.1 - 0.047 12.6 2.4 0.074 11.9 2.4 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF3829 PF12889.7 PVD22047.1 - 0.39 10.2 4.3 0.095 12.2 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) ABC_tran_CTD PF16326.5 PVD22047.1 - 0.88 9.9 3.7 6.4 7.1 0.6 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF948 PF06103.11 PVD22047.1 - 1 9.6 6.1 0.56 10.5 2.1 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) LXG PF04740.12 PVD22047.1 - 1.1 8.9 9.5 0.41 10.3 4.9 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily RICH PF05062.12 PVD22047.1 - 1.3 9.5 10.8 0.11 12.9 3.0 2.8 2 1 0 3 3 3 0 RICH domain TMPIT PF07851.13 PVD22047.1 - 1.8 7.8 10.7 0.19 10.9 6.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 PVD22047.1 - 1.9 8.6 12.0 0.62 10.1 5.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PVD22047.1 - 2.9 8.4 7.8 1.2 9.7 2.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM167 PF11652.8 PVD22047.1 - 4.2 7.9 10.8 0.3 11.6 1.2 3.0 2 1 1 3 3 3 0 FAM167 COG2 PF06148.11 PVD22047.1 - 7.5 6.6 11.5 3.6 7.7 4.0 3.2 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 PVD22047.1 - 8.5 7.0 8.2 5.1 7.7 0.3 2.6 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 PVD22047.1 - 8.6 7.2 7.0 14 6.5 3.9 2.6 2 1 0 2 2 2 0 Occludin homology domain CENP-H PF05837.12 PVD22047.1 - 9.8 6.6 12.3 1.9 8.9 6.9 2.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) zf-C3HC4_3 PF13920.6 PVD22048.1 - 1.5e-10 40.8 6.0 1.5e-10 40.8 6.0 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22048.1 - 2.5e-09 37.0 4.7 2.5e-09 37.0 4.7 4.2 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD22048.1 - 5.7e-09 35.7 9.9 5.7e-09 35.7 9.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22048.1 - 1.3e-08 34.5 8.3 1.3e-08 34.5 8.3 3.8 3 3 2 5 5 5 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22048.1 - 1.5e-08 34.3 10.8 1.5e-08 34.3 10.8 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22048.1 - 2.9e-08 33.9 9.5 2.9e-08 33.9 9.5 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD22048.1 - 2.6e-07 30.5 6.3 2.6e-07 30.5 6.3 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22048.1 - 1.9e-06 27.9 10.7 1.9e-06 27.9 10.7 3.5 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22048.1 - 0.00012 22.1 5.7 0.00012 22.1 5.7 4.3 4 1 0 4 4 4 2 B-box zinc finger ArfGap PF01412.18 PVD22048.1 - 0.0033 17.5 2.5 0.0033 17.5 2.5 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn_Tnp_IS91 PF14319.6 PVD22048.1 - 0.023 14.7 3.0 0.023 14.7 3.0 2.7 2 1 0 2 2 2 0 Transposase zinc-binding domain Siva PF05458.12 PVD22048.1 - 0.34 10.6 12.7 0.092 12.4 4.2 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-RING_11 PF17123.5 PVD22048.1 - 7.9 6.3 14.4 0.097 12.4 4.1 2.8 2 0 0 2 2 2 0 RING-like zinc finger Aldo_ket_red PF00248.21 PVD22049.1 - 1.3e-36 126.4 0.1 4e-34 118.2 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family HU-CCDC81_euk_1 PF14908.6 PVD22049.1 - 0.083 13.0 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 1 zf-C3HC4 PF00097.25 PVD22050.1 - 2.1e-06 27.5 0.6 2.1e-06 27.5 0.6 3.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22050.1 - 2.7e-06 27.4 2.3 2.7e-06 27.4 2.3 3.8 3 1 0 3 3 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD22050.1 - 4.5e-05 23.4 2.9 4.5e-05 23.4 2.9 3.0 3 0 0 3 3 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD22050.1 - 5.3e-05 23.0 2.2 5.3e-05 23.0 2.2 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22050.1 - 0.00014 21.7 4.2 0.00014 21.7 4.2 3.5 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22050.1 - 0.00018 21.8 4.2 0.00018 21.8 4.2 3.8 4 0 0 4 4 3 1 Ring finger domain Fibin PF15819.5 PVD22050.1 - 0.0032 17.3 0.5 0.0074 16.1 0.5 1.5 1 0 0 1 1 1 1 Fin bud initiation factor homologue Phasin PF05597.11 PVD22050.1 - 0.011 15.7 0.5 0.029 14.4 0.5 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HsbA PF12296.8 PVD22050.1 - 0.048 14.1 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 PVD22050.1 - 0.19 11.8 1.4 0.96 9.5 1.4 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OrfB_IS605 PF01385.19 PVD22050.1 - 0.38 11.0 2.5 0.81 9.9 0.5 2.3 2 1 0 2 2 2 0 Probable transposase Occludin_ELL PF07303.13 PVD22050.1 - 1.8 9.3 5.5 2.1 9.1 2.1 2.6 2 1 0 2 2 2 0 Occludin homology domain LMBR1 PF04791.16 PVD22050.1 - 2.6 6.8 3.5 3.4 6.5 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CEBP_ZZ PF16366.5 PVD22050.1 - 3.4 8.0 15.1 2.2 8.6 1.5 3.7 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1664 PF07889.12 PVD22050.1 - 4 7.5 8.0 1.9 8.6 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.6 PVD22051.1 - 5e-10 39.1 4.8 5e-10 39.1 4.8 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22051.1 - 6.1e-09 35.6 6.9 6.1e-09 35.6 6.9 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22051.1 - 4e-08 33.5 6.9 4e-08 33.5 6.9 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD22051.1 - 5.4e-07 29.3 8.1 5.4e-07 29.3 8.1 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22051.1 - 2.4e-06 27.5 7.2 2.4e-06 27.5 7.2 2.5 3 0 0 3 3 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22051.1 - 3.6e-06 26.7 7.0 3.6e-06 26.7 7.0 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22051.1 - 5.1e-06 26.5 8.0 5.1e-06 26.5 8.0 2.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22051.1 - 8.4e-06 25.8 17.7 0.00022 21.3 5.8 3.9 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD22051.1 - 1.2e-05 25.2 5.3 1.2e-05 25.2 5.3 3.5 3 1 1 4 4 2 1 zinc-RING finger domain Neuralized PF07177.12 PVD22051.1 - 0.00092 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Neuralized DUF3552 PF12072.8 PVD22051.1 - 0.00096 18.6 1.4 0.0015 18.0 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF1664 PF07889.12 PVD22051.1 - 0.009 16.1 5.5 0.65 10.1 1.9 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD22051.1 - 0.011 15.7 0.5 0.021 14.7 0.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 PVD22051.1 - 0.028 14.4 0.6 0.063 13.3 0.6 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5082 PF16888.5 PVD22051.1 - 0.032 14.5 1.1 0.12 12.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Sigma70_ner PF04546.13 PVD22051.1 - 0.043 13.7 0.2 0.08 12.8 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Laminin_II PF06009.12 PVD22051.1 - 0.099 12.7 2.1 0.23 11.5 2.1 1.5 1 0 0 1 1 1 0 Laminin Domain II PhoU PF01895.19 PVD22051.1 - 0.11 13.0 0.4 0.27 11.7 0.4 1.7 1 0 0 1 1 1 0 PhoU domain Exonuc_VII_L PF02601.15 PVD22051.1 - 0.11 12.0 0.5 0.22 11.0 0.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit RPW8 PF05659.11 PVD22051.1 - 0.13 12.0 0.8 4.4 7.0 0.2 2.4 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1640 PF07798.11 PVD22051.1 - 0.14 12.2 2.1 0.91 9.5 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) HSCB_C PF07743.13 PVD22051.1 - 1.4 9.4 3.9 1.4 9.4 1.7 2.1 2 1 0 2 2 1 0 HSCB C-terminal oligomerisation domain ArfGap PF01412.18 PVD22051.1 - 2.5 8.2 24.7 0.62 10.2 6.9 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-RING_10 PF16685.5 PVD22051.1 - 2.8 8.1 20.1 0.68 10.1 4.5 3.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 PVD22052.1 - 4.4e-09 36.0 9.4 4.4e-09 36.0 9.4 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD22052.1 - 4.7e-09 36.0 8.3 4.7e-09 36.0 8.3 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22052.1 - 8.3e-09 35.2 11.1 8.3e-09 35.2 11.1 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22052.1 - 2.4e-08 34.0 37.6 6.6e-06 26.2 4.3 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD22052.1 - 3.4e-08 33.7 8.5 3.4e-08 33.7 8.5 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD22052.1 - 1.5e-06 28.0 9.4 1.5e-06 28.0 9.4 2.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22052.1 - 2.6e-06 27.3 7.6 2.6e-06 27.3 7.6 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22052.1 - 5.9e-06 26.3 10.3 5.9e-06 26.3 10.3 3.6 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22052.1 - 0.00029 20.7 10.8 0.00029 20.7 10.8 4.0 3 1 1 4 4 2 1 zinc-RING finger domain DUF3829 PF12889.7 PVD22052.1 - 0.0011 18.5 1.3 0.013 15.0 1.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3829) Apolipoprotein PF01442.18 PVD22052.1 - 0.0052 16.7 4.6 0.013 15.4 4.6 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 PVD22052.1 - 0.025 14.6 12.4 0.2 11.7 3.9 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) TelA PF05816.11 PVD22052.1 - 0.035 13.2 5.3 0.017 14.2 2.8 1.7 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) ApoC-I PF04691.12 PVD22052.1 - 0.039 13.9 0.7 0.22 11.5 0.1 2.4 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) Baculo_PEP_C PF04513.12 PVD22052.1 - 0.064 13.3 7.0 0.74 9.9 6.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5601 PF18151.1 PVD22052.1 - 0.075 13.4 0.2 3 8.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) DUF1465 PF07323.12 PVD22052.1 - 0.079 12.8 3.6 0.6 9.9 0.6 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1465) Spc7 PF08317.11 PVD22052.1 - 0.11 11.4 7.0 0.069 12.0 4.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Phasin PF05597.11 PVD22052.1 - 0.13 12.3 6.2 0.075 13.0 3.0 2.2 2 1 1 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YlbD_coat PF14071.6 PVD22052.1 - 0.18 12.1 4.9 0.4 10.9 1.9 2.4 2 0 0 2 2 2 0 Putative coat protein Phage_coat PF09063.10 PVD22052.1 - 0.19 11.8 2.1 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 Phage PP7 coat protein ING PF12998.7 PVD22052.1 - 0.32 11.6 4.8 0.23 12.1 2.5 2.1 2 0 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding COG2 PF06148.11 PVD22052.1 - 0.38 10.8 8.5 0.97 9.5 2.5 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 PVD22052.1 - 0.66 10.4 6.1 5.9 7.4 3.7 2.7 2 1 0 2 2 2 0 Snapin/Pallidin ArfGap PF01412.18 PVD22052.1 - 1.2 9.3 29.9 0.91 9.6 9.8 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Nsp1_C PF05064.13 PVD22052.1 - 1.7 8.5 6.4 6.3 6.6 1.5 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region Plasmid_RAQPRD PF09686.10 PVD22052.1 - 2.5 8.4 4.8 3.9 7.7 0.5 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) NPV_P10 PF05531.12 PVD22052.1 - 8.3 7.0 11.3 20 5.7 1.8 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-C3HC4 PF00097.25 PVD22053.1 - 9.3e-10 38.2 6.4 9.3e-10 38.2 6.4 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22053.1 - 2.8e-09 37.1 7.8 2.8e-09 37.1 7.8 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22053.1 - 5.1e-09 35.8 9.4 5.1e-09 35.8 9.4 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22053.1 - 2.6e-08 33.6 9.8 2.6e-08 33.6 9.8 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22053.1 - 4.6e-08 32.9 6.4 4.6e-08 32.9 6.4 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.24 PVD22053.1 - 8.3e-08 32.3 33.5 7.5e-05 22.8 9.7 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22053.1 - 4.2e-07 29.7 8.2 4.2e-07 29.7 8.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22053.1 - 2.8e-05 24.2 7.7 2.8e-05 24.2 7.7 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22053.1 - 8.7e-05 22.4 8.3 8.7e-05 22.4 8.3 3.9 3 1 1 4 4 4 1 zinc-RING finger domain ArfGap PF01412.18 PVD22053.1 - 0.052 13.6 28.2 0.034 14.2 8.6 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Phasin PF05597.11 PVD22053.1 - 0.077 13.0 4.1 0.064 13.3 0.9 2.4 3 0 0 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PVD22053.1 - 0.16 12.0 4.7 0.38 10.8 3.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_lipo_1 PF05714.11 PVD22053.1 - 0.38 10.5 3.7 8.4 6.1 0.4 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein FAM167 PF11652.8 PVD22053.1 - 1.3 9.6 11.1 0.17 12.4 0.7 3.3 3 1 1 4 4 3 0 FAM167 DUF1664 PF07889.12 PVD22053.1 - 5 7.2 11.7 19 5.3 6.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 PVD22053.1 - 7.2 6.6 18.7 0.052 13.4 6.2 3.3 3 0 0 3 3 3 0 HIT zinc finger zf-C3HC4 PF00097.25 PVD22054.1 - 1.1e-08 34.8 10.1 1.1e-08 34.8 10.1 3.9 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22054.1 - 2e-08 34.3 22.5 1.2e-05 25.3 4.6 4.2 4 1 0 4 4 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD22054.1 - 3.4e-08 33.7 11.0 3.4e-08 33.7 11.0 4.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22054.1 - 1.1e-07 31.6 41.6 1.4e-07 31.2 12.1 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22054.1 - 3.5e-07 30.0 13.2 3.5e-07 30.0 13.2 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22054.1 - 1.4e-06 28.2 9.9 1.4e-06 28.2 9.9 3.0 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22054.1 - 0.00066 19.8 10.8 0.00066 19.8 10.8 3.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING COG2 PF06148.11 PVD22054.1 - 0.0042 17.2 2.1 0.0095 16.0 1.5 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ArfGap PF01412.18 PVD22054.1 - 0.0045 17.0 29.8 0.005 16.9 8.1 3.6 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf Cob_adeno_trans PF01923.18 PVD22054.1 - 0.0059 16.8 2.9 0.68 10.0 0.2 2.4 1 1 1 2 2 2 2 Cobalamin adenosyltransferase DUF1465 PF07323.12 PVD22054.1 - 0.014 15.2 0.8 0.36 10.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) zf-RING_5 PF14634.6 PVD22054.1 - 0.014 15.3 12.4 0.014 15.3 12.4 4.5 4 1 1 5 5 4 0 zinc-RING finger domain Fibin PF15819.5 PVD22054.1 - 0.026 14.3 0.9 0.052 13.3 0.9 1.4 1 0 0 1 1 1 0 Fin bud initiation factor homologue Baculo_PEP_C PF04513.12 PVD22054.1 - 0.026 14.6 2.5 0.82 9.7 1.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MHC_I_2 PF14586.6 PVD22054.1 - 0.03 14.2 0.3 0.058 13.3 0.3 1.5 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 DUF1664 PF07889.12 PVD22054.1 - 0.03 14.4 7.4 0.067 13.2 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 PVD22054.1 - 0.042 13.9 2.3 0.093 12.7 2.3 1.5 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.12 PVD22054.1 - 0.95 10.0 6.2 2.4 8.7 4.3 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2408 PF10303.9 PVD22054.1 - 4.9 7.7 8.2 6.2 7.4 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) zf-C3HC4 PF00097.25 PVD22055.1 - 5.3e-10 39.0 6.8 5.3e-10 39.0 6.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22055.1 - 2.1e-08 34.3 7.9 2.1e-08 34.3 7.9 3.9 4 0 0 4 4 4 1 Ring finger domain zf-B_box PF00643.24 PVD22055.1 - 2.5e-08 33.9 17.3 2.6e-05 24.3 4.4 4.4 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22055.1 - 1e-07 31.7 38.4 1.9e-07 30.8 10.8 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD22055.1 - 1.5e-07 31.1 8.4 1.5e-07 31.1 8.4 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22055.1 - 1.6e-07 31.2 8.0 1.6e-07 31.2 8.0 3.3 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22055.1 - 1.7e-07 31.0 11.0 1.7e-07 31.0 11.0 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22055.1 - 9e-06 25.7 7.3 9e-06 25.7 7.3 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22055.1 - 0.00042 20.2 9.4 0.00042 20.2 9.4 4.3 4 1 1 5 5 4 1 zinc-RING finger domain 5_nucleotid PF05761.14 PVD22055.1 - 0.00082 18.4 1.9 0.00082 18.4 1.9 1.6 2 0 0 2 2 2 1 5' nucleotidase family SUIM_assoc PF16619.5 PVD22055.1 - 0.0044 17.1 1.3 0.011 15.8 1.3 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Baculo_PEP_C PF04513.12 PVD22055.1 - 0.089 12.8 6.3 0.095 12.7 0.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 PVD22055.1 - 1.1 8.7 15.3 0.058 12.8 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) FH2 PF02181.23 PVD22055.1 - 8.2 5.4 13.8 0.098 11.8 5.2 2.1 3 0 0 3 3 3 0 Formin Homology 2 Domain zf-C3HC4 PF00097.25 PVD22056.1 - 7.5e-10 38.5 9.7 7.5e-10 38.5 9.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22056.1 - 6e-09 35.9 34.5 3e-05 24.1 4.6 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD22056.1 - 1.6e-08 34.3 40.8 3e-08 33.4 11.8 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22056.1 - 4.1e-08 33.4 10.3 4.1e-08 33.4 10.3 3.7 4 0 0 4 4 4 2 Ring finger domain Prok-RING_4 PF14447.6 PVD22056.1 - 5.3e-08 32.6 11.4 5.3e-08 32.6 11.4 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22056.1 - 1.4e-06 28.0 10.6 1.4e-06 28.0 10.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22056.1 - 3e-06 27.3 8.3 3e-06 27.3 8.3 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD22056.1 - 4.1e-06 26.7 13.4 4.1e-06 26.7 13.4 3.3 3 1 0 3 3 3 1 RING-type zinc-finger 5_nucleotid PF05761.14 PVD22056.1 - 0.0008 18.4 1.2 0.0011 17.9 1.2 1.2 1 0 0 1 1 1 1 5' nucleotidase family Leu_zip PF15294.6 PVD22056.1 - 0.0035 16.9 4.7 0.0059 16.2 4.7 1.3 1 0 0 1 1 1 1 Leucine zipper zf-RING_5 PF14634.6 PVD22056.1 - 0.012 15.6 12.2 0.012 15.6 12.2 4.1 3 1 1 4 4 3 0 zinc-RING finger domain FH2 PF02181.23 PVD22056.1 - 0.038 13.1 2.3 0.064 12.4 2.3 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Baculo_PEP_C PF04513.12 PVD22056.1 - 0.039 14.0 1.4 2.4 8.2 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 PVD22056.1 - 0.22 10.9 5.2 0.2 11.1 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 PVD22056.1 - 1.6 8.7 10.2 3 7.9 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 PVD22056.1 - 1.8 8.5 16.4 0.054 13.4 5.4 3.4 3 0 0 3 3 3 0 HIT zinc finger zf-C3HC4 PF00097.25 PVD22057.1 - 3.6e-10 39.5 6.6 3.6e-10 39.5 6.6 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22057.1 - 2.2e-08 34.1 18.1 2.4e-05 24.4 5.0 4.1 4 1 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD22057.1 - 2.7e-08 34.0 7.8 2.7e-08 34.0 7.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22057.1 - 3.8e-08 33.1 9.9 3.8e-08 33.1 9.9 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22057.1 - 1.2e-07 31.5 10.4 1.2e-07 31.5 10.4 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22057.1 - 3.3e-07 30.0 8.1 3.3e-07 30.0 8.1 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22057.1 - 1.3e-06 28.3 11.2 1.3e-06 28.3 11.2 3.5 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22057.1 - 4.8e-06 26.6 7.5 4.8e-06 26.6 7.5 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22057.1 - 0.00082 19.3 9.2 0.00082 19.3 9.2 4.2 3 1 0 3 3 2 1 zinc-RING finger domain Baculo_PEP_C PF04513.12 PVD22057.1 - 0.0072 16.4 0.2 0.0072 16.4 0.2 2.6 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus PIN_3 PF13470.6 PVD22057.1 - 0.065 14.0 0.9 0.57 11.0 0.1 2.5 2 0 0 2 2 2 0 PIN domain DUF3552 PF12072.8 PVD22057.1 - 0.76 9.2 17.3 0.011 15.1 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ArfGap PF01412.18 PVD22057.1 - 0.88 9.7 33.4 0.29 11.2 5.3 4.3 3 1 1 4 4 4 0 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 PVD22057.1 - 1.5 8.9 13.0 4.3 7.5 13.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PspA_IM30 PF04012.12 PVD22057.1 - 1.8 8.1 14.2 0.39 10.3 1.2 2.3 2 0 0 2 2 2 0 PspA/IM30 family OmpH PF03938.14 PVD22057.1 - 2.7 8.3 17.0 0.69 10.2 7.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PhnG PF06754.12 PVD22057.1 - 2.7 7.9 6.2 0.58 10.1 2.2 1.9 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG zf-B_box PF00643.24 PVD22058.1 - 6.8e-12 45.3 21.1 9.8e-06 25.6 4.0 2.5 2 0 0 2 2 2 2 B-box zinc finger DUF3829 PF12889.7 PVD22058.1 - 0.0013 18.3 0.9 0.0021 17.6 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) ArfGap PF01412.18 PVD22058.1 - 0.0029 17.7 19.4 0.0079 16.3 8.0 2.5 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf TelA PF05816.11 PVD22058.1 - 0.0035 16.5 3.7 0.0055 15.8 3.7 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 PVD22058.1 - 0.011 15.7 3.3 0.022 14.6 3.3 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 PVD22058.1 - 0.02 13.8 4.7 0.03 13.2 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-HIT PF04438.16 PVD22058.1 - 0.02 14.7 6.6 0.02 14.7 6.6 2.6 2 1 1 3 3 3 0 HIT zinc finger Baculo_PEP_C PF04513.12 PVD22058.1 - 0.022 14.8 5.0 0.14 12.2 4.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 PVD22058.1 - 0.024 14.0 1.7 0.036 13.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2408 PF10303.9 PVD22058.1 - 0.033 14.8 3.1 0.057 14.0 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CLZ PF16526.5 PVD22058.1 - 0.043 14.2 3.4 0.22 11.9 0.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 PVD22058.1 - 0.089 12.9 4.7 0.18 11.8 4.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 PVD22058.1 - 0.1 13.2 3.0 0.95 10.1 0.2 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 PVD22058.1 - 0.13 12.3 10.4 0.29 11.2 5.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RmuC PF02646.16 PVD22058.1 - 0.13 11.4 4.7 0.11 11.5 1.7 2.0 1 1 1 2 2 2 0 RmuC family Phasin PF05597.11 PVD22058.1 - 0.17 11.9 5.3 0.35 10.9 3.6 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COG2 PF06148.11 PVD22058.1 - 0.2 11.8 6.2 0.71 10.0 2.4 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 PVD22058.1 - 0.31 10.6 14.0 0.077 12.6 9.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 PVD22058.1 - 0.35 10.1 5.2 0.52 9.5 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Bacillus_HBL PF05791.11 PVD22058.1 - 0.53 10.1 4.7 1.3 8.9 4.1 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1465 PF07323.12 PVD22058.1 - 0.84 9.5 4.9 8.6 6.2 1.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1465) V_ATPase_I PF01496.19 PVD22058.1 - 1.1 7.0 5.8 2 6.2 4.6 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FAM167 PF11652.8 PVD22058.1 - 1.4 9.4 7.0 0.36 11.4 0.7 2.8 2 1 1 3 3 3 0 FAM167 DUF1640 PF07798.11 PVD22058.1 - 1.9 8.5 9.3 6.4 6.8 9.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YlbD_coat PF14071.6 PVD22058.1 - 2.1 8.6 5.5 2.1 8.6 3.0 2.2 2 1 1 3 3 3 0 Putative coat protein NPV_P10 PF05531.12 PVD22058.1 - 3.1 8.3 8.7 8.8 6.9 2.8 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.6 PVD22058.1 - 8.9 6.3 22.8 0.05 13.5 11.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22059.1 - 1.3e-10 41.3 30.8 8.2e-06 25.9 2.5 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22059.1 - 3.8e-10 39.5 6.1 3.8e-10 39.5 6.1 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22059.1 - 6.5e-10 38.7 39.2 1.8e-09 37.3 8.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22059.1 - 5.2e-09 36.3 7.3 5.2e-09 36.3 7.3 3.5 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22059.1 - 2.2e-08 33.8 9.4 2.2e-08 33.8 9.4 3.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22059.1 - 2.9e-08 33.6 5.3 2.9e-08 33.6 5.3 2.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22059.1 - 3.7e-07 29.9 7.6 3.7e-07 29.9 7.6 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22059.1 - 6.8e-06 26.1 6.9 6.8e-06 26.1 6.9 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22059.1 - 0.00011 22.0 8.4 0.00011 22.0 8.4 3.7 3 1 1 4 4 2 1 zinc-RING finger domain Neuralized PF07177.12 PVD22059.1 - 0.00023 21.2 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Neuralized Golgin_A5 PF09787.9 PVD22059.1 - 0.00089 18.8 2.6 0.0014 18.2 2.6 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 AAA_32 PF13654.6 PVD22059.1 - 0.0036 16.2 1.6 0.0045 15.8 1.6 1.1 1 0 0 1 1 1 1 AAA domain Arb1 PF09692.10 PVD22059.1 - 0.0052 16.0 0.2 0.36 9.9 0.2 2.1 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Spc7 PF08317.11 PVD22059.1 - 0.0085 15.0 5.7 0.013 14.4 5.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PVD22059.1 - 0.015 15.4 5.2 0.079 13.0 5.2 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3829 PF12889.7 PVD22059.1 - 0.017 14.6 1.4 0.033 13.6 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) LMP PF04778.12 PVD22059.1 - 0.017 15.0 5.1 0.031 14.2 5.1 1.3 1 0 0 1 1 1 0 LMP repeated region Apolipoprotein PF01442.18 PVD22059.1 - 0.019 14.8 5.5 0.047 13.6 5.5 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YscO-like PF16789.5 PVD22059.1 - 0.026 14.6 3.9 0.041 13.9 3.9 1.3 1 0 0 1 1 1 0 YscO-like protein ArfGap PF01412.18 PVD22059.1 - 0.037 14.1 28.6 0.034 14.2 8.5 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Phasin PF05597.11 PVD22059.1 - 0.042 13.9 5.9 0.045 13.8 3.1 2.5 3 1 1 4 4 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HsbA PF12296.8 PVD22059.1 - 0.057 13.9 0.4 0.14 12.6 0.4 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A YlbD_coat PF14071.6 PVD22059.1 - 0.061 13.6 2.0 0.15 12.3 2.0 1.7 1 0 0 1 1 1 0 Putative coat protein NACHT_N PF17100.5 PVD22059.1 - 0.13 12.1 2.1 0.2 11.5 2.1 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Syntaxin-6_N PF09177.11 PVD22059.1 - 0.15 12.6 6.0 1.2 9.7 0.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF745 PF05335.13 PVD22059.1 - 0.17 11.5 2.1 0.31 10.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 PVD22059.1 - 0.21 11.1 3.1 0.3 10.6 3.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec20 PF03908.13 PVD22059.1 - 0.25 11.3 1.9 0.67 9.9 1.9 1.8 1 0 0 1 1 1 0 Sec20 Muted PF14942.6 PVD22059.1 - 0.29 11.5 5.2 0.56 10.6 5.2 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FAM167 PF11652.8 PVD22059.1 - 0.31 11.6 7.1 0.18 12.3 0.8 3.1 2 1 1 3 3 3 0 FAM167 Baculo_PEP_C PF04513.12 PVD22059.1 - 0.56 10.3 9.2 0.17 11.9 4.4 2.4 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 PVD22059.1 - 0.68 9.1 3.3 1.1 8.5 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein ING PF12998.7 PVD22059.1 - 0.8 10.3 6.8 3.2 8.4 5.6 2.5 2 1 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HIT PF04438.16 PVD22059.1 - 0.94 9.4 15.1 0.061 13.2 6.2 3.2 3 0 0 3 3 2 0 HIT zinc finger Fez1 PF06818.15 PVD22059.1 - 1 9.8 9.5 7.5 6.9 6.6 2.0 1 1 1 2 2 2 0 Fez1 Med9 PF07544.13 PVD22059.1 - 1.4 9.1 5.4 3.8 7.7 5.5 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 PVD22059.1 - 1.4 9.4 9.0 1.2 9.7 0.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 PVD22059.1 - 1.8 8.7 6.8 6.7 6.8 3.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 PVD22059.1 - 1.8 8.6 10.7 1.9 8.5 5.4 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Plasmid_RAQPRD PF09686.10 PVD22059.1 - 2.2 8.5 6.2 1.1 9.5 0.6 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-rbx1 PF12678.7 PVD22059.1 - 4.7 7.6 24.5 0.045 14.0 5.3 4.0 3 1 0 3 3 2 0 RING-H2 zinc finger domain MAGI_u5 PF16666.5 PVD22060.1 - 0.27 11.4 3.5 0.24 11.5 2.6 1.3 1 1 0 1 1 1 0 Unstructured region on MAGI zf-C3HC4 PF00097.25 PVD22061.1 - 3.5e-10 39.6 6.3 3.5e-10 39.6 6.3 3.5 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22061.1 - 3.9e-09 36.2 9.6 3.9e-09 36.2 9.6 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22061.1 - 8.8e-09 35.6 7.4 8.8e-09 35.6 7.4 4.0 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22061.1 - 2.3e-08 33.7 9.4 2.3e-08 33.7 9.4 3.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22061.1 - 6.6e-08 32.6 21.3 4.5e-05 23.5 3.8 4.2 4 1 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD22061.1 - 8.3e-08 32.1 6.7 8.3e-08 32.1 6.7 2.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22061.1 - 4.8e-07 29.5 8.0 4.8e-07 29.5 8.0 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22061.1 - 3.5e-06 27.1 7.0 3.5e-06 27.1 7.0 3.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22061.1 - 0.00017 21.5 8.8 0.00017 21.5 8.8 4.6 4 2 1 5 5 3 1 zinc-RING finger domain Phasin PF05597.11 PVD22061.1 - 0.00065 19.7 1.1 0.0019 18.2 1.1 1.8 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 PVD22061.1 - 0.0032 17.5 6.7 0.015 15.3 4.9 2.7 1 1 1 3 3 3 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 PVD22061.1 - 0.0058 16.7 2.2 0.0097 15.9 2.2 1.3 1 0 0 1 1 1 1 Laminin Domain II DUF2408 PF10303.9 PVD22061.1 - 0.017 15.7 2.5 0.029 14.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF3450 PF11932.8 PVD22061.1 - 0.02 14.2 0.4 0.029 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ArfGap PF01412.18 PVD22061.1 - 0.028 14.5 8.2 0.028 14.5 8.2 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Golgin_A5 PF09787.9 PVD22061.1 - 0.033 13.6 2.6 0.047 13.2 2.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tup_N PF08581.10 PVD22061.1 - 0.034 14.4 0.2 0.088 13.1 0.2 1.7 1 0 0 1 1 1 0 Tup N-terminal NPV_P10 PF05531.12 PVD22061.1 - 0.037 14.5 4.6 3.3 8.2 4.1 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ING PF12998.7 PVD22061.1 - 0.069 13.8 1.8 0.18 12.4 1.5 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Cob_adeno_trans PF01923.18 PVD22061.1 - 0.08 13.1 2.6 1.1 9.4 2.6 2.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Baculo_PEP_C PF04513.12 PVD22061.1 - 0.085 12.9 3.2 0.57 10.2 2.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 PVD22061.1 - 0.087 13.2 2.6 0.13 12.6 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1465 PF07323.12 PVD22061.1 - 0.11 12.3 1.5 3.1 7.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) MtrB PF05440.12 PVD22061.1 - 0.16 12.4 0.4 25 5.4 0.1 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B COG2 PF06148.11 PVD22061.1 - 0.17 12.0 5.9 0.2 11.7 3.9 2.1 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 PVD22061.1 - 0.18 11.4 11.1 0.087 12.4 7.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Spc24 PF08286.11 PVD22061.1 - 0.21 11.9 1.5 0.48 10.7 1.5 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 PVD22061.1 - 0.27 11.5 2.6 0.73 10.1 0.6 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Muted PF14942.6 PVD22061.1 - 0.36 11.2 4.9 0.72 10.2 4.9 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein TMPIT PF07851.13 PVD22061.1 - 0.36 10.0 2.6 0.52 9.5 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.6 PVD22061.1 - 0.43 11.0 5.5 1.1 9.7 4.7 2.1 2 0 0 2 2 2 0 Snapin/Pallidin CLZ PF16526.5 PVD22061.1 - 1.1 9.7 5.8 0.55 10.6 0.7 2.7 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 PVD22061.1 - 4.3 7.6 4.7 5.6 7.2 1.0 2.5 1 1 1 2 2 2 0 Haemolysin XhlA CENP-H PF05837.12 PVD22061.1 - 8.6 6.8 9.2 7.1 7.1 6.1 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) zf-C3HC4 PF00097.25 PVD22062.1 - 1.6e-09 37.5 7.7 1.6e-09 37.5 7.7 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22062.1 - 8e-09 35.2 10.3 8e-09 35.2 10.3 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22062.1 - 9.9e-09 35.4 8.8 9.9e-09 35.4 8.8 3.4 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD22062.1 - 1.4e-08 34.6 6.5 1.4e-08 34.6 6.5 2.7 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22062.1 - 4.3e-08 32.9 10.7 4.3e-08 32.9 10.7 3.6 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22062.1 - 8e-06 25.9 8.6 8e-06 25.9 8.6 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22062.1 - 2.1e-05 24.6 26.1 5e-05 23.4 9.8 4.0 4 1 0 4 4 3 2 B-box zinc finger zf-RING_5 PF14634.6 PVD22062.1 - 6.1e-05 22.9 9.3 6.1e-05 22.9 9.3 3.9 3 1 1 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD22062.1 - 0.0009 19.3 9.1 0.0009 19.3 9.1 3.3 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf YlbD_coat PF14071.6 PVD22062.1 - 0.091 13.0 0.8 0.2 11.9 0.8 1.6 1 0 0 1 1 1 0 Putative coat protein Baculo_PEP_C PF04513.12 PVD22062.1 - 0.13 12.3 5.8 0.52 10.3 4.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 PVD22062.1 - 0.4 10.7 3.8 0.34 10.9 1.4 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Borrelia_lipo_1 PF05714.11 PVD22062.1 - 0.76 9.5 5.4 5.4 6.7 0.4 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Snapin_Pallidin PF14712.6 PVD22062.1 - 0.85 10.1 6.0 3.2 8.2 2.8 2.6 2 0 0 2 2 2 0 Snapin/Pallidin FAM167 PF11652.8 PVD22062.1 - 2.2 8.8 9.2 0.11 13.0 0.9 2.9 3 1 1 4 4 3 0 FAM167 DUF1664 PF07889.12 PVD22062.1 - 4.4 7.4 11.9 1.2 9.2 3.3 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Prok-RING_4 PF14447.6 PVD22063.1 - 4.3e-09 36.1 9.4 4.3e-09 36.1 9.4 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD22063.1 - 4.5e-09 36.0 8.3 4.5e-09 36.0 8.3 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22063.1 - 7.9e-09 35.2 11.1 7.9e-09 35.2 11.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22063.1 - 3.2e-08 33.8 8.5 3.2e-08 33.8 8.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-B_box PF00643.24 PVD22063.1 - 5e-08 33.0 36.3 1.4e-05 25.1 3.1 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD22063.1 - 1.4e-06 28.0 9.4 1.4e-06 28.0 9.4 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22063.1 - 2.6e-06 27.4 7.6 2.6e-06 27.4 7.6 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22063.1 - 5.7e-06 26.4 10.3 5.7e-06 26.4 10.3 3.4 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22063.1 - 0.00028 20.8 10.8 0.00028 20.8 10.8 3.9 3 1 1 4 4 2 1 zinc-RING finger domain DUF3829 PF12889.7 PVD22063.1 - 0.003 17.1 1.9 0.007 15.9 1.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3829) DUF1465 PF07323.12 PVD22063.1 - 0.015 15.1 3.9 0.24 11.2 0.8 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1465) Baculo_PEP_C PF04513.12 PVD22063.1 - 0.025 14.6 6.6 0.1 12.6 4.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 PVD22063.1 - 0.049 12.5 6.9 0.033 13.1 4.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 PVD22063.1 - 0.053 13.6 13.3 0.46 10.5 4.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) YlbD_coat PF14071.6 PVD22063.1 - 0.11 12.7 5.3 0.08 13.2 2.4 2.1 2 0 0 2 2 2 0 Putative coat protein Apolipoprotein PF01442.18 PVD22063.1 - 0.17 11.7 6.9 0.27 11.1 5.9 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FAM167 PF11652.8 PVD22063.1 - 0.18 12.3 3.4 0.23 12.0 0.5 2.5 1 1 1 2 2 2 0 FAM167 Phasin PF05597.11 PVD22063.1 - 0.19 11.7 7.2 0.082 12.9 3.5 2.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COG2 PF06148.11 PVD22063.1 - 0.22 11.6 8.5 2.3 8.3 4.0 3.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 PVD22063.1 - 0.22 9.4 4.7 1.2 6.9 3.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Phage_coat PF09063.10 PVD22063.1 - 0.52 10.3 4.5 1.7 8.7 0.1 3.0 2 1 1 3 3 3 0 Phage PP7 coat protein Plasmid_RAQPRD PF09686.10 PVD22063.1 - 1.2 9.3 5.4 1.5 9.1 0.8 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) NPV_P10 PF05531.12 PVD22063.1 - 1.4 9.4 12.5 13 6.4 2.5 3.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 PVD22063.1 - 1.7 9.1 8.2 13 6.3 4.9 2.9 2 1 0 2 2 2 0 Snapin/Pallidin ArfGap PF01412.18 PVD22063.1 - 1.8 8.7 29.9 1.1 9.4 10.0 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf CLZ PF16526.5 PVD22063.1 - 2.6 8.5 8.1 5.1 7.5 0.4 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin-6_N PF09177.11 PVD22063.1 - 3.7 8.2 7.3 3.3 8.3 0.3 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1640 PF07798.11 PVD22063.1 - 8.2 6.4 12.0 5.1 7.1 9.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) zf-C3HC4_3 PF13920.6 PVD22064.1 - 9.2e-10 38.2 4.1 9.2e-10 38.2 4.1 3.1 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) Neuralized PF07177.12 PVD22064.1 - 8e-09 35.7 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Neuralized zf-C3HC4 PF00097.25 PVD22064.1 - 8.5e-09 35.2 5.4 8.5e-09 35.2 5.4 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22064.1 - 7.8e-08 32.5 5.8 7.8e-08 32.5 5.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-B_box PF00643.24 PVD22064.1 - 7.2e-07 29.3 30.2 8.5e-05 22.6 6.5 3.7 4 0 0 4 4 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22064.1 - 9.1e-07 28.6 5.7 9.1e-07 28.6 5.7 3.2 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22064.1 - 2.3e-06 27.3 7.3 2.3e-06 27.3 7.3 3.0 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22064.1 - 1e-05 25.5 7.1 1e-05 25.5 7.1 2.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD22064.1 - 1.4e-05 25.0 7.1 1.4e-05 25.0 7.1 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22064.1 - 4.7e-05 23.2 4.7 4.7e-05 23.2 4.7 3.5 3 1 1 4 4 3 1 zinc-RING finger domain DUF5082 PF16888.5 PVD22064.1 - 0.0028 17.9 0.4 0.18 12.1 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF3552 PF12072.8 PVD22064.1 - 0.0067 15.9 0.9 0.01 15.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF1664 PF07889.12 PVD22064.1 - 0.023 14.8 6.6 1.7 8.7 1.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD22064.1 - 0.075 12.9 0.7 0.17 11.7 0.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 PVD22064.1 - 0.077 13.0 1.8 0.25 11.4 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DDE_Tnp_1_3 PF13612.6 PVD22064.1 - 0.13 12.3 0.6 0.94 9.5 0.1 2.2 1 1 1 2 2 2 0 Transposase DDE domain Phasin PF05597.11 PVD22064.1 - 0.17 11.9 0.5 0.34 10.9 0.5 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RPW8 PF05659.11 PVD22064.1 - 0.17 11.6 1.6 6.9 6.4 0.3 2.4 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF445 PF04286.12 PVD22064.1 - 0.18 11.6 0.2 0.26 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ArfGap PF01412.18 PVD22064.1 - 2.1 8.4 25.1 0.71 10.0 6.7 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf OATP PF03137.20 PVD22065.1 - 2.9e-136 455.0 22.6 2.9e-136 455.0 22.6 1.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD22065.1 - 5e-22 78.3 24.9 1.9e-15 56.7 11.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD22065.1 - 3.6e-07 30.2 11.8 8.9e-07 28.9 11.8 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF4381 PF14316.6 PVD22065.1 - 0.025 14.8 0.0 0.09 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Kazal_1 PF00050.21 PVD22065.1 - 0.031 14.3 8.4 0.086 12.9 8.4 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Colicin_V PF02674.16 PVD22065.1 - 0.27 11.2 12.2 1.2 9.1 0.0 4.7 5 0 0 5 5 5 0 Colicin V production protein zf-C3HC4_3 PF13920.6 PVD22066.1 - 3.5e-07 30.0 9.7 3.5e-07 30.0 9.7 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22066.1 - 1.1e-06 28.4 9.5 1.1e-06 28.4 9.5 3.8 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD22066.1 - 3.4e-06 27.1 24.5 3.2e-05 24.0 7.7 4.0 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22066.1 - 8.4e-06 25.6 10.5 8.4e-06 25.6 10.5 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22066.1 - 1.4e-05 25.0 9.5 1.4e-05 25.0 9.5 4.3 4 1 1 5 5 3 1 zinc-RING finger domain Neuralized PF07177.12 PVD22066.1 - 3.7e-05 23.8 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Neuralized zf-RING_UBOX PF13445.6 PVD22066.1 - 4.5e-05 23.4 5.0 4.5e-05 23.4 5.0 3.5 4 1 0 4 4 1 1 RING-type zinc-finger ArfGap PF01412.18 PVD22066.1 - 0.00031 20.8 6.8 0.00031 20.8 6.8 4.0 4 1 1 5 5 4 1 Putative GTPase activating protein for Arf zf-RING_2 PF13639.6 PVD22066.1 - 0.00044 20.5 10.3 0.00044 20.5 10.3 4.3 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD22066.1 - 0.026 14.7 11.0 0.026 14.7 11.0 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING GAS PF13851.6 PVD22066.1 - 0.55 9.5 7.4 0.96 8.8 7.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Trimer_CC PF08954.11 PVD22066.1 - 1 9.0 4.9 1.2 8.7 0.1 2.9 3 1 0 3 3 3 0 Trimerisation motif COG2 PF06148.11 PVD22066.1 - 1.2 9.2 7.5 4.7 7.3 5.8 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 PVD22066.1 - 6.2 6.3 6.2 8.7 5.8 4.2 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit ACCA PF03255.14 PVD22066.1 - 6.7 6.6 6.1 2.3 8.1 0.5 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit zf-C3HC4 PF00097.25 PVD22067.1 - 2e-10 40.4 7.1 2e-10 40.4 7.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22067.1 - 9.3e-09 35.5 8.0 9.3e-09 35.5 8.0 4.1 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22067.1 - 2.8e-08 33.5 9.7 2.8e-08 33.5 9.7 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD22067.1 - 6.9e-08 32.5 17.2 4.3e-05 23.6 4.8 4.2 4 1 0 4 4 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD22067.1 - 1.6e-07 31.1 11.0 1.6e-07 31.1 11.0 4.0 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22067.1 - 8.7e-07 28.7 7.6 8.7e-07 28.7 7.6 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22067.1 - 1.3e-06 28.3 11.3 1.3e-06 28.3 11.3 3.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD22067.1 - 4e-06 26.9 7.6 4e-06 26.9 7.6 3.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22067.1 - 0.0033 17.4 9.4 0.0033 17.4 9.4 4.2 3 1 1 4 4 3 1 zinc-RING finger domain DUF4795 PF16043.5 PVD22067.1 - 0.0072 15.9 5.8 0.02 14.5 5.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) LMP PF04778.12 PVD22067.1 - 0.021 14.7 3.1 0.041 13.8 3.1 1.4 1 0 0 1 1 1 0 LMP repeated region TMP_2 PF06791.13 PVD22067.1 - 0.027 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein ApoLp-III PF07464.11 PVD22067.1 - 0.029 14.5 2.0 0.078 13.1 2.0 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3450 PF11932.8 PVD22067.1 - 0.029 13.7 0.5 0.047 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) STAT_alpha PF01017.20 PVD22067.1 - 0.05 13.5 3.8 0.093 12.6 3.8 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.11 PVD22067.1 - 0.078 13.5 2.0 0.18 12.4 0.9 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Cor1 PF04803.12 PVD22067.1 - 0.084 13.1 3.4 0.15 12.3 3.4 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region DUF1664 PF07889.12 PVD22067.1 - 0.1 12.6 8.1 0.44 10.6 4.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD22067.1 - 0.1 12.4 3.2 0.069 13.0 1.3 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Gp-FAR-1 PF05823.12 PVD22067.1 - 0.1 12.9 0.8 0.26 11.6 0.8 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF948 PF06103.11 PVD22067.1 - 0.11 12.8 4.0 8.5 6.7 0.6 2.9 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.9 PVD22067.1 - 0.14 12.3 3.4 4.5 7.5 1.6 2.9 1 1 2 3 3 3 0 Golgi transport complex subunit 5 CorA PF01544.18 PVD22067.1 - 0.22 10.8 1.9 0.14 11.4 0.2 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ArfGap PF01412.18 PVD22067.1 - 0.25 11.4 25.5 0.41 10.7 5.1 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Prefoldin PF02996.17 PVD22067.1 - 0.59 10.1 5.6 2.2 8.2 0.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 PVD22067.1 - 0.63 8.9 4.7 1.1 8.1 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 PVD22067.1 - 0.87 9.6 7.9 1.3 9.0 0.2 2.9 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 PVD22067.1 - 0.94 9.5 5.7 22 5.1 2.5 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KELK PF15796.5 PVD22067.1 - 1.5 9.3 5.5 2.8 8.4 0.3 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf-C3HC4_3 PF13920.6 PVD22070.1 - 3.3e-16 58.9 22.3 5e-10 39.1 5.0 6.0 6 0 0 6 6 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22070.1 - 4.6e-16 58.4 21.7 2.6e-09 36.8 6.8 5.4 5 0 0 5 5 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22070.1 - 2.3e-14 53.5 23.6 1.5e-08 34.8 7.9 6.5 5 1 1 6 6 3 2 Ring finger domain zf-RING_UBOX PF13445.6 PVD22070.1 - 5.9e-13 48.6 21.8 1.5e-08 34.5 6.4 4.7 5 2 0 5 5 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD22070.1 - 5.3e-11 42.2 25.7 2.9e-08 33.4 9.6 5.6 5 0 0 5 5 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22070.1 - 5.9e-11 42.1 24.5 3.4e-07 30.0 10.0 6.3 7 1 1 8 8 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD22070.1 - 1.6e-10 41.0 24.7 3e-08 33.7 9.9 5.9 6 0 0 6 6 2 2 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22070.1 - 4.5e-09 36.3 68.3 0.00011 22.3 6.2 7.7 7 1 0 7 7 6 4 B-box zinc finger zf-RING_5 PF14634.6 PVD22070.1 - 1.8e-07 31.0 22.6 6.1e-06 26.1 5.3 6.7 4 2 1 5 5 3 2 zinc-RING finger domain DUF1664 PF07889.12 PVD22070.1 - 0.00017 21.6 11.4 0.0025 17.9 2.5 3.6 2 1 0 3 3 3 1 Protein of unknown function (DUF1664) DUF4795 PF16043.5 PVD22070.1 - 0.00072 19.2 4.9 0.077 12.6 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) Phasin PF05597.11 PVD22070.1 - 0.01 15.9 11.0 0.017 15.1 1.0 3.7 3 1 1 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Borrelia_lipo_1 PF05714.11 PVD22070.1 - 0.011 15.5 8.2 0.013 15.3 3.4 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein HlyD_2 PF12700.7 PVD22070.1 - 0.019 13.7 4.9 0.41 9.3 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein Mating_N PF12731.7 PVD22070.1 - 0.026 14.6 2.2 6.1 7.0 0.2 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 EzrA PF06160.12 PVD22070.1 - 0.035 12.3 4.6 1.9 6.6 0.1 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 PVD22070.1 - 0.1 12.9 8.6 0.4 11.0 1.9 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 PVD22070.1 - 0.1 12.2 6.5 1.3 8.6 0.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4665 PF15679.5 PVD22070.1 - 0.11 13.2 5.0 5.2 7.8 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Apolipoprotein PF01442.18 PVD22070.1 - 0.13 12.1 12.6 0.33 10.8 4.0 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SesA PF17107.5 PVD22070.1 - 0.14 12.4 6.1 0.27 11.4 0.8 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases E2F_CC-MB PF16421.5 PVD22070.1 - 0.19 12.1 8.6 5.7 7.4 0.5 3.3 3 1 0 3 3 2 0 E2F transcription factor CC-MB domain Baculo_PEP_C PF04513.12 PVD22070.1 - 0.19 11.7 11.7 1.6 8.8 2.9 3.1 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 PVD22070.1 - 0.31 11.1 4.7 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sigma70_ner PF04546.13 PVD22070.1 - 0.32 10.9 5.0 5.5 6.8 0.3 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region LXG PF04740.12 PVD22070.1 - 0.4 10.4 8.9 4.1 7.1 2.4 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily SHE3 PF17078.5 PVD22070.1 - 0.42 10.3 8.6 4.4 7.0 0.5 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Prefoldin_2 PF01920.20 PVD22070.1 - 0.82 9.7 5.9 3.6 7.6 0.6 2.8 2 0 0 2 2 2 0 Prefoldin subunit MitMem_reg PF13012.6 PVD22070.1 - 0.95 9.9 4.5 0.67 10.4 0.1 2.8 3 0 0 3 3 2 0 Maintenance of mitochondrial structure and function COG2 PF06148.11 PVD22070.1 - 1.1 9.4 9.6 7 6.8 1.4 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HBM PF16591.5 PVD22070.1 - 1.2 8.6 8.8 9.1 5.6 0.5 3.0 2 1 1 3 3 3 0 Helical bimodular sensor domain Not3 PF04065.15 PVD22070.1 - 1.2 8.5 7.4 0.47 9.9 1.7 2.2 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.11 PVD22070.1 - 1.2 8.0 11.6 1.7 7.4 1.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein TEX13 PF15186.6 PVD22070.1 - 1.2 8.8 5.3 8.6 6.0 0.7 2.5 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF1640 PF07798.11 PVD22070.1 - 1.6 8.8 14.1 2.1 8.3 1.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1640) Phage_Mu_Gam PF07352.12 PVD22070.1 - 1.9 8.4 4.5 23 4.8 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ING PF12998.7 PVD22070.1 - 1.9 9.1 9.7 15 6.2 0.7 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin-6_N PF09177.11 PVD22070.1 - 2.7 8.6 8.4 0.42 11.2 0.4 3.0 3 1 0 3 3 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 PVD22070.1 - 2.8 7.1 9.0 4.7 6.4 2.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein ZapA PF05164.13 PVD22070.1 - 3.2 8.2 5.5 38 4.8 1.6 2.6 2 0 0 2 2 2 0 Cell division protein ZapA SKA2 PF16740.5 PVD22070.1 - 3.8 7.3 8.3 1.9 8.3 1.1 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF745 PF05335.13 PVD22070.1 - 4.5 7.0 12.1 7.1 6.3 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) T3SSipB PF16535.5 PVD22070.1 - 5.4 7.5 6.7 22 5.5 0.8 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Fzo_mitofusin PF04799.13 PVD22070.1 - 5.9 6.4 8.6 10 5.6 1.0 3.3 2 2 1 3 3 3 0 fzo-like conserved region APG6_N PF17675.1 PVD22070.1 - 5.9 7.4 14.6 1.3 9.5 0.3 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region YlqD PF11068.8 PVD22070.1 - 6.9 7.1 8.7 3.8 7.9 1.2 2.4 2 0 0 2 2 2 0 YlqD protein RasGAP_C PF03836.15 PVD22070.1 - 8.2 6.6 8.6 9.3 6.4 1.6 2.9 2 1 0 2 2 2 0 RasGAP C-terminus Fez1 PF06818.15 PVD22070.1 - 9.1 6.7 10.9 3.2 8.2 0.9 2.6 2 1 0 2 2 2 0 Fez1 zf-C3HC4 PF00097.25 PVD22071.1 - 1.8e-09 37.3 6.5 1.8e-09 37.3 6.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22071.1 - 3e-08 33.5 5.7 3e-08 33.5 5.7 2.8 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD22071.1 - 2.2e-07 30.6 8.7 2.2e-07 30.6 8.7 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22071.1 - 1.1e-06 28.4 9.2 1.1e-06 28.4 9.2 3.3 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD22071.1 - 3.8e-05 23.5 8.7 3.8e-05 23.5 8.7 4.0 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22071.1 - 0.00014 22.0 8.1 0.00014 22.0 8.1 3.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD22071.1 - 0.0008 19.5 6.1 0.0008 19.5 6.1 4.4 5 0 0 5 5 5 2 B-box zinc finger Cortex-I_coil PF09304.10 PVD22071.1 - 0.0015 18.7 5.6 0.015 15.5 0.5 2.4 2 0 0 2 2 2 1 Cortexillin I, coiled coil DUF948 PF06103.11 PVD22071.1 - 0.078 13.2 0.4 0.31 11.3 0.1 2.2 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Nnf1 PF03980.14 PVD22071.1 - 0.15 12.5 6.1 0.11 12.9 3.7 2.1 2 0 0 2 2 2 0 Nnf1 Apolipoprotein PF01442.18 PVD22071.1 - 0.3 11.0 7.8 0.33 10.8 6.5 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 PVD22071.1 - 0.36 10.9 5.0 0.2 11.7 0.5 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 PVD22071.1 - 0.46 11.1 2.1 2.5 8.7 2.1 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF883 PF05957.13 PVD22071.1 - 3.3 8.4 9.6 0.37 11.4 0.6 2.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 PVD22071.1 - 4.5 7.3 4.9 9 6.4 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 PVD22071.1 - 5.9 7.3 14.1 3.9 7.8 2.0 2.7 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) KfrA_N PF11740.8 PVD22071.1 - 7.4 7.3 9.7 11 6.7 5.8 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term zf-B_box PF00643.24 PVD22072.1 - 6.2e-09 35.9 17.7 8.3e-06 25.9 4.8 4.6 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD22072.1 - 2.1e-07 30.7 14.6 2.1e-07 30.7 14.6 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22072.1 - 1.2e-06 28.3 10.5 1.2e-06 28.3 10.5 3.2 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22072.1 - 1.1e-05 25.4 15.7 4.2e-05 23.5 15.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Neuralized PF07177.12 PVD22072.1 - 2e-05 24.6 0.0 7.3e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Neuralized zf-RING_5 PF14634.6 PVD22072.1 - 0.0014 18.5 13.2 0.0014 18.5 13.2 2.9 3 0 0 3 3 2 1 zinc-RING finger domain ApoLp-III PF07464.11 PVD22072.1 - 0.0023 18.0 4.0 0.005 16.9 4.0 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) zf-C3HC4_4 PF15227.6 PVD22072.1 - 0.0031 17.6 14.9 0.0031 17.6 14.9 3.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD22072.1 - 0.0066 16.8 14.4 0.0066 16.8 14.4 3.4 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD22072.1 - 0.0072 16.2 14.5 0.0072 16.2 14.5 3.5 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 FlaF PF07309.11 PVD22072.1 - 0.0096 15.9 0.3 0.019 15.0 0.3 1.5 1 0 0 1 1 1 1 Flagellar protein FlaF Dynamin_M PF01031.20 PVD22072.1 - 0.036 13.3 0.2 0.06 12.6 0.2 1.3 1 0 0 1 1 1 0 Dynamin central region Laminin_II PF06009.12 PVD22072.1 - 0.069 13.2 5.0 0.13 12.3 5.0 1.4 1 0 0 1 1 1 0 Laminin Domain II AAA_32 PF13654.6 PVD22072.1 - 0.11 11.3 2.1 0.14 10.9 2.1 1.1 1 0 0 1 1 1 0 AAA domain Cor1 PF04803.12 PVD22072.1 - 0.11 12.8 3.7 0.18 12.0 3.7 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Apolipoprotein PF01442.18 PVD22072.1 - 0.12 12.2 7.7 0.23 11.3 7.7 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain zinc_ribbon_9 PF14369.6 PVD22072.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon PXA PF02194.15 PVD22072.1 - 0.18 11.8 1.2 0.34 10.9 1.2 1.4 1 0 0 1 1 1 0 PXA domain TPR_MLP1_2 PF07926.12 PVD22072.1 - 0.24 11.5 5.2 0.22 11.6 0.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 PVD22072.1 - 0.44 10.6 5.5 0.44 10.6 2.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 PVD22072.1 - 0.71 10.5 4.4 2.2 8.9 1.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HNH PF01844.23 PVD22072.1 - 2.1 8.6 8.1 1.9 8.7 0.1 3.6 3 0 0 3 3 2 0 HNH endonuclease Spc7 PF08317.11 PVD22072.1 - 3.8 6.3 8.4 6 5.7 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein EGF PF00008.27 PVD22073.1 - 2.1e-206 667.3 592.5 2.8e-08 33.9 5.0 41.9 42 0 0 42 42 42 40 EGF-like domain hEGF PF12661.7 PVD22073.1 - 1.9e-111 361.4 525.5 2.4e-06 27.9 2.9 43.9 42 0 0 42 42 42 36 Human growth factor-like EGF Laminin_G_2 PF02210.24 PVD22073.1 - 1.8e-38 131.9 0.0 9.6e-14 52.0 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain EGF_CA PF07645.15 PVD22073.1 - 7.2e-38 128.5 605.1 8.1e-10 38.7 6.1 42.1 20 10 21 41 41 41 24 Calcium-binding EGF domain EGF_2 PF07974.13 PVD22073.1 - 2.5e-35 120.5 686.2 0.00021 21.6 4.7 42.0 40 2 1 41 41 41 30 EGF-like domain Laminin_G_1 PF00054.23 PVD22073.1 - 2.4e-28 99.0 0.0 1.4e-10 41.5 0.0 4.4 4 0 0 4 4 4 4 Laminin G domain EGF_3 PF12947.7 PVD22073.1 - 0.00061 19.9 7.0 0.00061 19.9 7.0 41.8 40 1 0 40 40 40 19 EGF domain 7tm_1 PF00001.21 PVD22074.1 - 1.4e-16 60.6 5.6 1.7e-16 60.3 5.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD22074.1 - 1.3e-06 28.3 3.2 1.7e-06 27.9 3.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD22074.1 - 8.3e-05 22.4 3.1 0.0001 22.2 3.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD22074.1 - 0.00063 19.2 2.2 0.00074 19.0 2.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PhzC-PhzF PF02567.16 PVD22075.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.5 1 1 0 1 1 1 0 Phenazine biosynthesis-like protein Sushi PF00084.20 PVD22076.1 - 6e-12 46.0 60.7 1e-05 26.0 5.7 8.3 8 0 0 8 8 8 4 Sushi repeat (SCR repeat) Laminin_G_3 PF13385.6 PVD22076.1 - 6e-09 36.2 0.2 1.5e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.13 PVD22076.1 - 2.3e-05 24.4 0.5 2.3e-05 24.4 0.5 2.3 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Notch PF00066.17 PVD22076.1 - 0.00062 20.2 46.9 0.0028 18.1 7.4 7.7 7 0 0 7 7 7 3 LNR domain Reprolysin_4 PF13583.6 PVD22076.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD22076.1 - 0.0039 17.4 0.1 0.0098 16.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD22076.1 - 0.0093 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 PVD22076.1 - 0.018 14.7 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Homeodomain PF00046.29 PVD22077.1 - 7.3e-18 64.2 0.2 7.3e-18 64.2 0.2 1.9 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 PVD22077.1 - 1.1e-10 41.5 8.9 2.1e-10 40.7 8.9 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 PVD22077.1 - 0.00015 21.6 0.0 0.00059 19.7 0.0 2.1 1 0 0 1 1 1 1 Homeobox KN domain ExoD PF06055.12 PVD22077.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD TPR_12 PF13424.6 PVD22078.1 - 4.1e-06 27.0 4.2 0.00045 20.5 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD22078.1 - 1.6e-05 24.6 6.5 0.18 12.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22078.1 - 0.00062 19.8 1.5 4 7.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD22078.1 - 0.00066 19.9 0.2 0.0024 18.1 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22078.1 - 0.0038 17.0 5.8 1.2 9.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 PVD22078.1 - 0.027 14.2 2.2 0.042 13.6 1.5 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF3808 PF10300.9 PVD22078.1 - 0.036 12.8 0.2 0.052 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) GldH_lipo PF14109.6 PVD22078.1 - 0.064 14.0 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 GldH lipoprotein TPR_9 PF13371.6 PVD22078.1 - 0.086 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD22078.1 - 0.14 12.5 0.7 0.28 11.5 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 PVD22078.1 - 0.14 12.1 0.2 0.14 12.1 0.2 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TPR_19 PF14559.6 PVD22078.1 - 0.18 12.3 3.3 1.1 9.8 1.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat CMAS PF02353.20 PVD22078.1 - 0.44 9.8 1.9 0.25 10.6 0.1 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TPR_6 PF13174.6 PVD22078.1 - 1.2 9.9 4.5 65 4.5 0.0 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 PVD22079.1 - 2.5e-08 33.7 11.7 2.5e-08 33.7 11.7 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22079.1 - 3.6e-08 33.1 7.6 3.6e-08 33.1 7.6 3.5 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) Neuralized PF07177.12 PVD22079.1 - 8e-08 32.4 0.0 2.1e-05 24.5 0.0 2.6 1 1 1 2 2 2 1 Neuralized zf-B_box PF00643.24 PVD22079.1 - 5.9e-07 29.5 37.1 7.6e-05 22.8 7.8 4.1 3 1 0 3 3 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD22079.1 - 5.5e-06 26.3 9.1 4.5e-05 23.4 9.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD22079.1 - 9.4e-06 25.4 10.1 9.4e-06 25.4 10.1 3.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22079.1 - 1.8e-05 25.0 11.1 1.8e-05 25.0 11.1 3.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD22079.1 - 0.0001 22.1 10.6 0.0001 22.1 10.6 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22079.1 - 0.00075 19.6 10.8 0.00075 19.6 10.8 3.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD22079.1 - 0.0022 17.9 9.5 0.0022 17.9 9.5 3.4 3 0 0 3 3 2 1 zinc-RING finger domain Fez1 PF06818.15 PVD22079.1 - 0.089 13.2 0.3 0.24 11.8 0.3 1.6 1 1 1 2 2 2 0 Fez1 ArfGap PF01412.18 PVD22079.1 - 4.9 7.2 30.2 0.028 14.5 6.8 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf MADF_DNA_bdg PF10545.9 PVD22080.1 - 1.1e-07 32.1 0.4 2.7e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 PVD22080.1 - 0.00026 21.3 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4887 PF16228.5 PVD22080.1 - 0.19 11.9 6.7 0.38 10.9 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) TraF_2 PF13729.6 PVD22080.1 - 3.2 7.1 6.3 0.59 9.5 2.2 1.8 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein GoLoco PF02188.17 PVD22081.1 - 9.1e-39 130.4 32.3 1.5e-09 37.2 0.6 4.4 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 PVD22081.1 - 1.4e-33 115.0 17.0 5.3e-12 45.9 1.4 4.3 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22081.1 - 8.5e-28 95.0 19.4 1.4e-05 24.7 0.2 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22081.1 - 5.1e-26 88.8 11.7 2e-05 24.3 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22081.1 - 1e-16 59.6 8.8 0.0015 18.5 0.2 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 PVD22081.1 - 1.4e-14 52.9 17.7 0.0004 20.3 0.3 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 PVD22081.1 - 6.1e-12 45.0 14.0 0.0024 17.7 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 PVD22081.1 - 2.2e-08 34.1 1.7 0.072 13.2 0.0 4.5 4 1 0 4 4 4 3 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 PVD22081.1 - 5.4e-08 32.7 1.3 0.15 12.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22081.1 - 1.6e-07 31.9 6.1 0.033 14.8 0.4 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD22081.1 - 1e-05 25.9 1.6 2.2 9.3 0.0 4.9 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD22081.1 - 0.0016 17.9 4.4 0.0058 16.0 3.7 2.1 1 1 1 2 2 2 1 MalT-like TPR region FliJ PF02050.16 PVD22081.1 - 0.05 13.8 0.7 0.43 10.8 0.6 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein TPR_17 PF13431.6 PVD22081.1 - 0.053 13.9 8.1 24 5.6 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD22081.1 - 0.081 13.2 4.3 60 4.0 1.6 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PVD22081.1 - 0.23 11.2 12.9 7.5 6.3 0.5 5.6 5 1 1 6 6 6 0 TPR repeat ANAPC5 PF12862.7 PVD22081.1 - 0.26 11.4 1.4 29 4.8 0.0 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 PVD22082.1 - 1.9e-13 50.0 26.1 0.4 11.6 0.0 12.7 9 4 6 15 15 13 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22082.1 - 4.5e-12 46.3 1.8 0.37 11.3 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat Suf PF05843.14 PVD22082.1 - 2.9e-10 40.6 19.6 0.0079 16.2 1.9 7.4 5 3 3 8 8 8 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 PVD22082.1 - 6.5e-09 35.2 15.1 0.017 15.2 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD22082.1 - 6.5e-08 32.8 9.9 0.2 12.0 0.0 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 PVD22082.1 - 2.1e-06 27.1 13.9 0.0005 19.3 0.1 5.6 3 3 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 PVD22082.1 - 3.4e-05 23.7 13.8 0.24 11.7 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD22082.1 - 5.4e-05 22.5 11.0 0.1 11.8 0.2 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22082.1 - 0.00033 20.5 1.7 0.74 10.0 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD22082.1 - 0.0011 19.0 17.6 2 8.4 0.9 7.3 5 2 3 8 8 8 3 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 PVD22082.1 - 0.0027 18.0 7.8 14 6.4 0.2 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 PVD22082.1 - 0.0045 17.1 0.1 0.091 13.1 0.0 3.4 2 0 0 2 2 2 1 PPR repeat TPR_1 PF00515.28 PVD22082.1 - 0.26 11.2 7.7 10 6.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD22082.1 - 1.3 8.9 0.0 1.3 8.9 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD22082.1 - 1.6 9.6 10.4 15 6.4 0.0 6.5 7 1 1 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22082.1 - 5.6 7.7 12.2 11 6.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Ctr PF04145.15 PVD22083.1 - 4.6e-30 105.2 9.2 2.6e-29 102.8 9.2 1.9 1 1 0 1 1 1 1 Ctr copper transporter family FKBP_C PF00254.28 PVD22084.1 - 2.7e-28 98.1 0.0 1.1e-27 96.2 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 PVD22084.1 - 0.00013 21.9 2.0 0.0003 20.7 2.0 1.6 1 0 0 1 1 1 1 WH1 domain Ribosomal_60s PF00428.19 PVD22084.1 - 0.016 15.8 8.9 0.016 15.8 8.9 3.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein FAM163 PF15069.6 PVD22084.1 - 0.43 11.0 5.6 0.15 12.5 1.0 2.8 2 0 0 2 2 2 0 FAM163 family CENP-B_dimeris PF09026.10 PVD22084.1 - 0.98 9.9 11.7 2.4 8.6 11.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3800 PF12686.7 PVD22084.1 - 2.1 9.0 4.1 1.2e+02 3.3 3.1 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) AMP-binding PF00501.28 PVD22085.1 - 2.5e-25 88.9 0.0 4.4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.7 PVD22085.1 - 3.6e-09 37.1 0.0 7.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22085.1 - 7.8e-09 35.6 0.1 1.1e-07 31.9 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD22085.1 - 2.7e-07 31.0 0.0 7.1e-05 23.3 0.0 2.5 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD22085.1 - 2e-06 28.0 0.4 0.0035 17.7 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD22085.1 - 2.8e-06 27.2 0.0 0.042 14.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Chlorophyllase2 PF12740.7 PVD22085.1 - 0.11 11.3 0.0 0.23 10.3 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme AMP-binding PF00501.28 PVD22086.1 - 3.3e-46 157.8 0.0 4.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD22086.1 - 0.00019 22.4 0.0 0.00036 21.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cNMP_binding PF00027.29 PVD22087.1 - 3.8e-47 158.3 2.3 9.9e-15 54.4 0.1 4.1 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.22 PVD22087.1 - 2.2e-24 86.8 0.0 4.4e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4487 PF14868.6 PVD22088.1 - 3.6e-49 168.0 22.7 3.4e-48 164.8 12.1 3.4 2 2 1 3 3 3 2 Domain of unknown function (DUF4487) GRP PF07172.11 PVD22089.1 - 0.0019 18.9 11.2 0.0029 18.3 11.2 1.3 1 0 0 1 1 1 1 Glycine rich protein family PIN_4 PF13638.6 PVD22090.1 - 1.5e-31 109.4 0.1 1.5e-31 109.4 0.1 2.5 2 1 0 2 2 2 1 PIN domain WW PF00397.26 PVD22090.1 - 1.1e-08 35.0 0.2 1.9e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 WW domain PIN_12 PF16289.5 PVD22090.1 - 0.0032 18.0 0.0 0.0032 18.0 0.0 2.3 3 0 0 3 3 3 1 PIN domain PIN_9 PF18477.1 PVD22090.1 - 0.0085 16.4 0.0 0.075 13.4 0.0 2.6 2 0 0 2 2 2 1 PIN like domain PIN_3 PF13470.6 PVD22090.1 - 0.067 14.0 0.2 0.42 11.4 0.0 2.5 2 2 0 2 2 2 0 PIN domain Glyco_hydro_47 PF01532.20 PVD22091.1 - 3.3e-159 530.7 0.0 4.2e-159 530.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSP70 PF00012.20 PVD22092.1 - 1.1e-267 889.1 9.9 1.2e-267 889.0 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD22092.1 - 1.8e-16 59.9 0.5 4.6e-15 55.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 PVD22092.1 - 0.0013 19.1 4.1 0.62 10.5 0.1 3.4 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 PVD22092.1 - 0.0035 16.4 1.7 0.29 10.1 1.7 2.8 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DUF4624 PF15417.6 PVD22092.1 - 0.0038 17.0 0.2 0.034 14.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.18 PVD22092.1 - 0.0062 15.8 1.4 0.035 13.4 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 PVD22092.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RFC1 PF08519.12 PVD22092.1 - 0.91 9.7 3.8 0.34 11.1 0.5 1.9 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain SH3_1 PF00018.28 PVD22095.1 - 1.2e-20 72.8 0.1 1.9e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 PVD22095.1 - 7.4e-17 61.2 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 PVD22095.1 - 5.9e-14 51.5 0.0 7.2e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PVD22095.1 - 2.2e-13 49.8 0.2 2.6e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 PVD22095.1 - 0.00011 22.1 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 PVD22095.1 - 0.13 12.7 1.6 0.17 12.4 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger double domain RhoGEF PF00621.20 PVD22096.1 - 2.8e-44 151.5 6.8 5.8e-44 150.5 6.8 1.6 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 PVD22096.1 - 4.4e-21 75.1 0.4 2.1e-20 72.9 0.0 2.3 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD22096.1 - 4.3e-16 58.5 0.2 1.8e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 CAMSAP CH domain CDC24 PF06395.11 PVD22096.1 - 0.00082 19.6 0.2 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 CDC24 Calponin RasGEF_N_2 PF14663.6 PVD22096.1 - 0.055 13.9 0.1 0.32 11.4 0.0 2.4 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Kelch_5 PF13854.6 PVD22098.1 - 1.5e-36 123.8 2.7 2.3e-07 30.6 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 PVD22098.1 - 5.6e-35 119.1 8.1 4.5e-08 33.0 0.1 6.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD22098.1 - 4.6e-33 111.9 2.7 7.3e-06 25.8 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 PVD22098.1 - 8.9e-33 111.6 2.9 3.2e-06 26.6 0.0 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PVD22098.1 - 9.5e-31 105.1 4.2 1.3e-06 28.4 0.0 5.4 3 1 2 5 5 5 5 Kelch motif Kelch_3 PF13415.6 PVD22098.1 - 2.3e-30 104.3 4.5 3.4e-10 39.9 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain nos_propeller_2 PF18793.1 PVD22098.1 - 0.097 13.0 0.1 1.6 9.1 0.1 2.8 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat 2 7tm_1 PF00001.21 PVD22099.1 - 8.8e-09 35.1 1.3 1.2e-08 34.6 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 PVD22099.1 - 0.016 15.5 0.6 0.025 14.9 0.3 1.4 1 1 0 1 1 1 0 Orf78 (ac78) CrgA PF06781.12 PVD22099.1 - 0.14 12.3 2.0 0.22 11.6 2.0 1.5 1 1 0 1 1 1 0 Cell division protein CrgA DUF2109 PF09882.9 PVD22099.1 - 0.22 11.6 6.6 0.34 10.9 6.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) DNase_II PF03265.15 PVD22100.1 - 1.2e-52 179.2 0.2 1.5e-52 178.9 0.2 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II COBRA1 PF06209.13 PVD22101.1 - 8.7e-206 684.3 2.8 1.2e-205 683.8 2.8 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) PI3K_P85_iSH2 PF16454.5 PVD22101.1 - 0.084 12.5 0.9 3.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Abhydrolase_1 PF00561.20 PVD22102.1 - 5.7e-06 26.2 0.0 7.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD22102.1 - 0.00072 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD22102.1 - 0.0009 19.9 0.0 0.0012 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PVD22102.1 - 0.044 13.3 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 PVD22103.1 - 4.4e-10 39.0 10.7 4.4e-10 39.0 10.7 2.3 2 1 0 3 3 3 1 Major Facilitator Superfamily NmrA PF05368.13 PVD22104.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Ndc80_HEC PF03801.13 PVD22104.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 HEC/Ndc80p family NmrA PF05368.13 PVD22105.1 - 1.2e-18 67.5 0.0 1.5e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PVD22105.1 - 3e-05 24.0 0.0 3.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 PVD22105.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Adeno_E3_CR2 PF02439.15 PVD22106.1 - 0.0093 15.7 1.1 0.02 14.7 1.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 7tm_1 PF00001.21 PVD22107.1 - 7.2e-36 123.9 0.6 1e-35 123.4 0.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD22107.1 - 3.9e-05 23.1 10.5 0.0042 16.4 0.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Sigma_reg_N PF13800.6 PVD22107.1 - 0.069 13.4 0.3 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal UbiA PF01040.18 PVD22107.1 - 1.2 8.3 10.9 0.097 11.9 1.3 3.0 3 1 0 3 3 3 0 UbiA prenyltransferase family RNase_T PF00929.24 PVD22108.1 - 1.5e-07 32.1 0.0 3.6e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Exonuclease DNA_pol_B_exo1 PF03104.19 PVD22108.1 - 0.00044 19.5 0.0 0.00093 18.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Acyl-CoA_ox_N PF14749.6 PVD22108.1 - 0.041 14.4 0.2 0.12 13.0 0.2 1.8 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Spectrin PF00435.21 PVD22109.1 - 0 1276.7 230.0 6e-27 94.2 3.0 20.3 20 0 0 20 20 20 20 Spectrin repeat EFhand_Ca_insen PF08726.10 PVD22109.1 - 2.8e-26 91.4 0.4 2.8e-26 91.4 0.4 3.4 4 0 0 4 4 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 PVD22109.1 - 7.6e-14 50.2 3.5 3.6e-07 29.3 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 PVD22109.1 - 1.1e-09 38.6 0.3 1.1e-09 38.6 0.3 4.6 5 0 0 5 5 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD22109.1 - 2.4e-09 36.4 3.1 1.6e-05 24.4 0.3 4.6 5 0 0 5 5 3 2 EF-hand domain EF-hand_5 PF13202.6 PVD22109.1 - 1.6e-08 33.6 0.6 0.0034 16.8 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD22109.1 - 1.7e-07 31.0 0.4 0.01 15.7 0.1 3.4 2 0 0 2 2 2 2 EF-hand domain pair SH3_1 PF00018.28 PVD22109.1 - 7.9e-05 22.2 0.0 0.00021 20.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD22109.1 - 0.014 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DUF5616 PF18481.1 PVD22109.1 - 0.051 13.9 5.8 19 5.6 0.0 5.5 7 0 0 7 7 6 0 Domain of unknown function (DUF5616) EF-hand_9 PF14658.6 PVD22109.1 - 0.061 13.7 0.2 1.3 9.4 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain PPP5 PF08321.12 PVD22109.1 - 0.16 12.3 1.3 0.69 10.3 0.0 2.9 2 0 0 2 2 2 0 PPP5 TPR repeat region GvpG PF05120.12 PVD22109.1 - 0.39 10.8 21.0 0.58 10.2 0.2 6.5 5 1 0 5 5 3 0 Gas vesicle protein G EF-hand_10 PF14788.6 PVD22109.1 - 0.47 10.3 4.0 0.26 11.2 0.3 2.6 3 0 0 3 3 3 0 EF hand zf-MIZ PF02891.20 PVD22109.1 - 0.66 9.8 4.3 6.8 6.5 0.2 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Matrilin_ccoil PF10393.9 PVD22109.1 - 0.78 9.7 8.6 38 4.3 0.1 6.3 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin TMEM154 PF15102.6 PVD22110.1 - 0.0016 18.3 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Ly49 PF08391.10 PVD22110.1 - 0.013 15.8 0.2 0.021 15.2 0.2 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Ninjurin PF04923.12 PVD22110.1 - 0.014 15.4 0.2 0.019 14.9 0.2 1.2 1 0 0 1 1 1 0 Ninjurin EphA2_TM PF14575.6 PVD22110.1 - 0.078 13.9 0.0 0.2 12.6 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5527 PF17665.1 PVD22110.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CcmD PF04995.14 PVD22110.1 - 1.8 8.7 6.0 1.9 8.6 0.2 2.4 2 1 0 2 2 2 0 Heme exporter protein D (CcmD) Homeodomain PF00046.29 PVD22113.1 - 7.9e-22 76.9 5.0 1.2e-21 76.3 5.0 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD22113.1 - 0.044 13.3 0.6 0.11 12.0 0.6 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PVD22113.1 - 0.081 12.8 0.3 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain EF-hand_1 PF00036.32 PVD22114.1 - 2.5e-13 48.6 7.0 0.018 14.6 0.2 6.2 4 2 2 6 6 6 5 EF hand EF-hand_7 PF13499.6 PVD22114.1 - 3.2e-10 40.3 8.5 6.4e-05 23.3 3.2 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD22114.1 - 8e-10 37.9 11.0 0.27 11.2 0.1 6.1 3 3 2 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 PVD22114.1 - 6e-09 35.0 4.0 0.0024 17.3 0.0 5.1 5 0 0 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.9 PVD22114.1 - 5.1e-08 33.2 2.7 0.05 13.9 0.2 3.2 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PVD22114.1 - 4.7e-05 23.1 8.7 0.25 11.2 0.1 5.4 2 2 4 6 6 6 3 EF-hand domain pair B2-adapt-app_C PF09066.10 PVD22114.1 - 0.15 12.1 1.3 54 3.9 0.1 3.1 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain EF-hand_4 PF12763.7 PVD22114.1 - 0.23 11.4 1.7 0.77 9.7 0.6 2.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PVD22114.1 - 0.64 10.3 12.3 31 4.9 4.4 4.7 2 1 2 4 4 4 0 Dockerin type I domain NT-C2 PF10358.9 PVD22115.1 - 1.8e-13 50.4 0.0 9.3e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins LpoB PF13036.6 PVD22116.1 - 0.019 14.9 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB FAD_SOX PF18371.1 PVD22117.1 - 7.6e-28 96.9 0.0 2.6e-27 95.2 0.0 1.9 2 0 0 2 2 2 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 PVD22117.1 - 1.2e-24 86.7 1.0 2.6e-23 82.4 0.5 2.6 2 0 0 2 2 2 1 Erv1 / Alr family QSOX_Trx1 PF18108.1 PVD22117.1 - 4.9e-15 55.6 0.0 1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 QSOX Trx-like domain WD-3 PF09765.9 PVD22117.1 - 0.037 13.4 0.2 0.061 12.7 0.2 1.3 1 0 0 1 1 1 0 WD-repeat region DUF1706 PF08020.11 PVD22117.1 - 0.083 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) DUF35_N PF12172.8 PVD22117.1 - 0.41 10.6 2.7 0.31 11.0 0.8 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Filament PF00038.21 PVD22118.1 - 4.3e-13 49.5 14.6 6.2e-13 49.0 14.6 1.3 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 PVD22118.1 - 7.4e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain APG6_N PF17675.1 PVD22118.1 - 0.00025 21.6 33.5 0.0036 17.8 9.8 2.0 1 1 1 2 2 2 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 PVD22118.1 - 0.003 17.6 11.5 0.0064 16.6 11.5 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PVD22118.1 - 0.0043 16.4 6.5 0.0043 16.4 6.5 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF3450) DivIC PF04977.15 PVD22118.1 - 0.0045 16.7 7.4 0.065 13.0 1.6 3.1 1 1 2 3 3 3 2 Septum formation initiator PRKG1_interact PF15898.5 PVD22118.1 - 0.0068 17.3 9.7 0.022 15.6 7.5 2.4 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 PVD22118.1 - 0.0075 15.4 6.7 0.0075 15.4 6.7 2.0 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC144C PF14915.6 PVD22118.1 - 0.012 14.8 9.4 0.017 14.2 9.4 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Seryl_tRNA_N PF02403.22 PVD22118.1 - 0.017 15.3 8.2 0.033 14.4 2.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.9 PVD22118.1 - 0.019 15.0 13.9 0.19 11.7 13.6 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 STAT_alpha PF01017.20 PVD22118.1 - 0.035 14.0 3.4 0.062 13.2 3.4 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain NPV_P10 PF05531.12 PVD22118.1 - 0.036 14.5 1.3 4.7 7.8 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 PVD22118.1 - 0.036 14.7 5.6 0.036 14.7 5.6 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tektin PF03148.14 PVD22118.1 - 0.038 12.7 13.2 0.14 10.9 3.8 2.1 1 1 1 2 2 2 0 Tektin family Golgin_A5 PF09787.9 PVD22118.1 - 0.041 13.3 10.1 0.065 12.7 10.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 PVD22118.1 - 0.043 12.7 10.8 0.056 12.3 9.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 PVD22118.1 - 0.058 13.6 11.0 1.7 8.9 10.6 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain ING PF12998.7 PVD22118.1 - 0.06 13.9 5.7 0.073 13.7 4.3 1.8 2 0 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4140 PF13600.6 PVD22118.1 - 0.065 13.7 9.5 1.1 9.7 1.1 3.1 2 2 2 4 4 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 PVD22118.1 - 0.086 12.2 4.9 0.11 11.8 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T6SS_VasJ PF16989.5 PVD22118.1 - 0.09 12.2 3.6 0.15 11.5 3.6 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ AAA_13 PF13166.6 PVD22118.1 - 0.09 11.4 3.7 0.14 10.8 3.7 1.3 1 0 0 1 1 1 0 AAA domain DUF4201 PF13870.6 PVD22118.1 - 0.095 12.4 10.2 0.083 12.6 7.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TLE_N PF03920.15 PVD22118.1 - 0.11 12.6 1.4 0.28 11.3 1.4 1.7 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Ada3 PF10198.9 PVD22118.1 - 0.11 12.7 4.6 0.17 12.0 4.6 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF5129 PF17173.4 PVD22118.1 - 0.12 11.5 2.6 0.17 10.9 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Fez1 PF06818.15 PVD22118.1 - 0.12 12.8 11.5 0.2 12.1 11.5 1.6 1 1 0 1 1 1 0 Fez1 Spc24 PF08286.11 PVD22118.1 - 0.19 11.9 11.0 2.2 8.6 2.2 2.8 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 GAS PF13851.6 PVD22118.1 - 0.21 10.9 12.4 0.33 10.3 11.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 PVD22118.1 - 0.28 11.4 11.3 3 8.1 6.7 2.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 PVD22118.1 - 0.28 9.7 5.6 0.43 9.1 5.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 PVD22118.1 - 0.28 11.2 1.9 0.77 9.8 1.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_UL6 PF01763.16 PVD22118.1 - 0.3 9.5 2.6 0.41 9.1 2.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Cep57_MT_bd PF06657.13 PVD22118.1 - 0.34 11.4 11.0 0.46 11.0 6.4 3.0 2 1 1 3 3 1 0 Centrosome microtubule-binding domain of Cep57 CEP209_CC5 PF16574.5 PVD22118.1 - 0.35 11.0 8.8 0.21 11.8 2.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 Cep57_CLD_2 PF14197.6 PVD22118.1 - 0.39 10.9 12.8 0.45 10.6 11.5 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 TMPIT PF07851.13 PVD22118.1 - 0.42 9.8 3.9 0.62 9.3 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 PVD22118.1 - 0.44 10.4 6.8 1.1 9.1 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 PVD22118.1 - 0.6 10.8 8.1 14 6.4 2.8 2.9 1 1 2 3 3 3 0 SlyX TSC22 PF01166.18 PVD22118.1 - 0.67 10.3 8.5 1.3 9.4 1.4 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family UPF0242 PF06785.11 PVD22118.1 - 0.67 10.0 9.3 1 9.5 9.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RasGAP_C PF03836.15 PVD22118.1 - 0.74 10.0 5.8 12 6.1 5.9 2.3 1 1 0 1 1 1 0 RasGAP C-terminus Prefoldin PF02996.17 PVD22118.1 - 0.76 9.7 6.0 0.96 9.4 1.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit BST2 PF16716.5 PVD22118.1 - 0.8 10.3 7.4 3 8.5 5.4 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ZapB PF06005.12 PVD22118.1 - 0.84 10.1 13.1 46 4.6 12.6 2.7 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 PVD22118.1 - 0.98 10.1 8.4 8.5 7.1 2.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA FUSC PF04632.12 PVD22118.1 - 1.1 7.7 4.7 1.3 7.4 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HalX PF08663.10 PVD22118.1 - 1.4 9.3 9.4 1.4 9.3 0.3 2.6 1 1 1 2 2 2 0 HalX domain Val_tRNA-synt_C PF10458.9 PVD22118.1 - 1.8 8.9 8.1 1.2 9.5 2.4 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm TMF_DNA_bd PF12329.8 PVD22118.1 - 1.9 8.5 13.4 1 9.4 7.6 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0184 PF03670.13 PVD22118.1 - 2.4 8.6 7.3 6.4 7.2 0.8 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) AATF-Che1 PF13339.6 PVD22118.1 - 4.4 8.0 7.5 8.5 7.1 7.3 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-H PF05837.12 PVD22118.1 - 5.6 7.4 9.7 8 6.9 8.1 2.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Bcr-Abl_Oligo PF09036.10 PVD22118.1 - 6.6 6.8 7.6 1.8 8.6 0.4 2.7 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Filament PF00038.21 PVD22119.1 - 3.5e-05 23.5 4.5 4.7e-05 23.1 4.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.8 PVD22119.1 - 0.00067 19.8 2.2 0.00088 19.4 2.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 PVD22119.1 - 0.002 18.3 0.5 0.0039 17.4 0.5 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.20 PVD22119.1 - 0.0022 17.4 5.7 0.0031 16.9 5.7 1.3 1 0 0 1 1 1 1 Tropomyosin Fib_alpha PF08702.10 PVD22119.1 - 0.0029 17.8 0.6 0.0043 17.3 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DivIC PF04977.15 PVD22119.1 - 0.022 14.5 2.0 0.13 12.0 1.4 2.5 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 PVD22119.1 - 0.028 13.5 1.6 0.033 13.3 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 PVD22119.1 - 0.036 13.7 5.1 0.14 11.8 5.1 1.9 1 1 0 1 1 1 0 GrpE Cob_adeno_trans PF01923.18 PVD22119.1 - 0.049 13.8 0.2 0.061 13.5 0.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CorA PF01544.18 PVD22119.1 - 0.052 12.9 5.2 0.073 12.4 5.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MscS_porin PF12795.7 PVD22119.1 - 0.054 13.0 2.8 0.082 12.4 2.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YabA PF06156.13 PVD22119.1 - 0.056 14.1 0.8 0.21 12.2 0.8 1.9 1 1 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 PVD22119.1 - 0.059 12.6 0.3 0.068 12.4 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mer2 PF09074.10 PVD22119.1 - 0.078 12.8 0.4 0.12 12.1 0.4 1.5 1 1 0 1 1 1 0 Mer2 Herpes_UL6 PF01763.16 PVD22119.1 - 0.079 11.5 0.1 0.096 11.2 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Fez1 PF06818.15 PVD22119.1 - 0.093 13.2 0.9 0.1 13.0 0.9 1.2 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.6 PVD22119.1 - 0.093 11.4 1.6 0.12 11.0 1.6 1.2 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 PVD22119.1 - 0.11 11.8 1.6 0.34 10.2 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 PVD22119.1 - 0.12 12.8 1.2 0.31 11.5 1.2 1.9 1 1 0 1 1 1 0 Cell division protein ZapB BLOC1_2 PF10046.9 PVD22119.1 - 0.13 12.6 3.0 0.21 11.9 0.7 2.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40_alt PF14077.6 PVD22119.1 - 0.13 12.1 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 1 0 Alternative WD40 repeat motif FlaC_arch PF05377.11 PVD22119.1 - 0.14 12.6 0.5 3.8 8.0 0.0 2.6 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) GAS PF13851.6 PVD22119.1 - 0.17 11.2 4.0 0.25 10.7 4.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 PVD22119.1 - 0.21 12.0 0.4 0.21 12.0 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 PVD22119.1 - 0.22 11.6 3.4 3.3 7.9 0.1 2.6 2 1 1 3 3 2 0 bZIP transcription factor APG6_N PF17675.1 PVD22119.1 - 0.27 11.8 5.0 0.63 10.6 5.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5082 PF16888.5 PVD22119.1 - 0.29 11.4 4.6 1 9.7 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 PVD22119.1 - 0.31 10.4 2.0 0.38 10.1 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 PVD22119.1 - 0.38 10.5 4.9 1 9.1 4.9 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 TcdB_N PF12918.7 PVD22119.1 - 0.42 10.9 3.2 1.5 9.2 1.9 2.2 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain TMF_DNA_bd PF12329.8 PVD22119.1 - 3.3 7.8 5.8 1.6 8.8 1.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Filament PF00038.21 PVD22120.1 - 4.5e-19 69.2 6.5 5.3e-19 68.9 6.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein KRAP_IP3R_bind PF14722.6 PVD22120.1 - 0.064 13.0 0.6 0.096 12.4 0.3 1.6 1 1 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain YabA PF06156.13 PVD22120.1 - 0.11 13.1 3.6 0.2 12.3 3.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA PRKG1_interact PF15898.5 PVD22120.1 - 0.37 11.7 8.7 0.51 11.3 3.1 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1640 PF07798.11 PVD22120.1 - 0.5 10.4 4.5 9.3 6.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) ZapB PF06005.12 PVD22120.1 - 0.65 10.5 8.7 1.2 9.7 7.5 2.0 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 PVD22120.1 - 1 9.5 13.2 1.2 9.3 9.3 2.6 2 2 0 2 2 2 0 Basic region leucine zipper ATPgrasp_N PF18130.1 PVD22123.1 - 0.00014 22.3 0.1 0.00037 21.0 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain DUF1495 PF07381.11 PVD22123.1 - 0.035 13.9 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Papo_T_antigen PF02380.15 PVD22123.1 - 0.32 11.2 2.3 0.66 10.2 2.3 1.4 1 0 0 1 1 1 0 T-antigen specific domain Fcf2 PF08698.11 PVD22124.1 - 3.5e-24 85.0 1.9 3.5e-24 85.0 1.9 2.6 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing TSC22 PF01166.18 PVD22124.1 - 0.0005 20.3 4.1 5.8 7.3 0.1 4.0 3 0 0 3 3 3 2 TSC-22/dip/bun family FlaC_arch PF05377.11 PVD22124.1 - 0.033 14.6 5.6 4 7.9 0.3 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Seadorna_VP6 PF07407.11 PVD22124.1 - 0.25 10.3 2.5 0.14 11.1 0.2 1.6 2 0 0 2 2 2 0 Seadornavirus VP6 protein DivIC PF04977.15 PVD22124.1 - 0.41 10.4 19.8 0.33 10.7 4.7 4.1 3 1 1 4 4 4 0 Septum formation initiator Nup54 PF13874.6 PVD22124.1 - 1 9.5 25.5 0.022 14.9 16.4 2.7 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 HALZ PF02183.18 PVD22124.1 - 3 8.1 13.4 1.1 9.6 1.1 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Pkinase PF00069.25 PVD22125.1 - 3.5e-45 154.4 0.0 3.9e-42 144.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22125.1 - 1.6e-17 63.7 0.0 6.3e-17 61.7 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD22125.1 - 8.7e-07 28.5 0.9 2.2e-06 27.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 PVD22125.1 - 1.5e-06 28.8 2.1 4.4e-06 27.3 2.1 2.0 1 1 0 1 1 1 1 Protein kinase C terminal domain ATG16 PF08614.11 PVD22125.1 - 0.0019 18.4 10.1 0.0053 17.0 10.1 1.8 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SOGA PF11365.8 PVD22125.1 - 0.0094 17.1 4.0 0.025 15.7 4.0 1.7 1 0 0 1 1 1 1 Protein SOGA Seadorna_VP7 PF07387.11 PVD22125.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 HALZ PF02183.18 PVD22125.1 - 0.033 14.4 1.2 0.033 14.4 1.2 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper APH PF01636.23 PVD22125.1 - 0.044 13.7 0.1 0.044 13.7 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD22125.1 - 0.05 12.5 4.0 0.058 12.3 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 PVD22125.1 - 0.081 12.3 1.8 0.096 12.0 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FlaC_arch PF05377.11 PVD22125.1 - 0.48 10.9 2.3 2.8 8.4 0.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Herpes_BLRF2 PF05812.12 PVD22125.1 - 1 9.5 6.2 8.3 6.6 1.5 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Cep57_MT_bd PF06657.13 PVD22125.1 - 2.3 8.7 8.5 0.36 11.3 0.2 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 PVD22125.1 - 3.9 7.3 15.6 0.25 11.1 4.3 3.0 2 1 1 3 3 3 0 Septum formation initiator Cu2_monoox_C PF03712.15 PVD22126.1 - 7.3e-51 171.8 0.1 1.4e-50 170.9 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD22126.1 - 1.9e-42 144.6 0.0 3.4e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 PVD22126.1 - 1.8e-08 34.7 0.7 4.2e-08 33.4 0.7 1.7 1 0 0 1 1 1 1 DOMON domain C1q PF00386.21 PVD22126.1 - 4.1e-08 33.5 0.0 1.6e-07 31.5 0.0 2.1 1 0 0 1 1 1 1 C1q domain DUF812 PF05667.11 PVD22126.1 - 0.0015 17.6 18.9 0.0023 16.9 18.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 PVD22126.1 - 0.27 11.4 30.4 0.13 12.5 13.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 PVD22126.1 - 0.32 10.2 35.4 0.47 9.6 7.4 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TSC22 PF01166.18 PVD22126.1 - 0.89 9.9 8.8 3.6 8.0 0.2 3.6 3 1 0 3 3 3 0 TSC-22/dip/bun family SOGA PF11365.8 PVD22126.1 - 1.1 10.5 14.6 0.073 14.2 5.0 2.8 2 1 0 2 2 2 0 Protein SOGA bZIP_1 PF00170.21 PVD22126.1 - 3.7 7.7 16.8 3.5 7.8 0.5 3.8 3 1 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 PVD22126.1 - 4 7.3 19.5 0.96 9.3 1.1 4.4 3 1 1 4 4 4 0 Septum formation initiator IFP_35_N PF07334.13 PVD22126.1 - 4.2 7.5 9.7 1.4 9.1 1.2 2.8 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SRCR PF00530.18 PVD22127.1 - 1.5e-163 532.4 43.2 6.3e-29 100.4 1.5 8.4 7 1 1 8 8 8 7 Scavenger receptor cysteine-rich domain HYR PF02494.16 PVD22127.1 - 1e-32 112.3 11.9 2.6e-16 59.7 1.8 3.0 3 0 0 3 3 2 2 HYR domain Sushi PF00084.20 PVD22127.1 - 1.5e-23 83.1 46.8 2.7e-08 34.3 4.4 6.3 6 0 0 6 6 6 4 Sushi repeat (SCR repeat) SRCR_2 PF15494.6 PVD22127.1 - 7.8e-22 77.7 19.2 0.00033 21.1 0.4 7.0 6 0 0 6 6 6 5 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 PVD22127.1 - 2.5e-21 75.9 7.6 1.4e-12 47.9 0.2 4.2 4 0 0 4 4 4 2 Low-density lipoprotein receptor repeat class B Hepsin-SRCR PF09272.10 PVD22127.1 - 7.1e-10 39.4 0.0 1.9 9.0 0.0 5.7 6 0 0 6 6 5 3 Hepsin, SRCR domain SKG6 PF08693.10 PVD22127.1 - 7.7e-06 25.2 1.9 2.5e-05 23.6 1.9 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SGL PF08450.12 PVD22127.1 - 2.6e-05 23.9 0.4 0.00016 21.4 0.2 2.2 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 PVD22127.1 - 0.002 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) He_PIG PF05345.12 PVD22127.1 - 0.04 14.1 3.3 0.075 13.2 0.2 3.2 2 0 0 2 2 2 0 Putative Ig domain Adeno_E3_CR2 PF02439.15 PVD22127.1 - 0.2 11.4 3.5 0.51 10.1 3.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 cEGF PF12662.7 PVD22127.1 - 3.2 7.8 19.6 6.2 6.9 1.3 5.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like HRM PF02793.22 PVD22127.1 - 6.6 7.1 25.3 0.034 14.5 2.8 5.4 4 0 0 4 4 4 0 Hormone receptor domain SRCR PF00530.18 PVD22128.1 - 8.2e-159 517.2 34.0 1.6e-28 99.1 0.7 8.4 8 1 1 9 9 9 8 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD22128.1 - 1.3e-22 80.1 2.3 0.00013 22.4 0.0 5.7 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22128.1 - 6.3e-12 46.0 0.1 0.083 13.4 0.0 5.0 4 1 0 4 4 4 4 Hepsin, SRCR domain zf_PR_Knuckle PF18445.1 PVD22128.1 - 0.0068 16.2 0.9 0.83 9.5 0.0 4.1 4 0 0 4 4 4 1 PR zinc knuckle motif Prok-RING_1 PF14446.6 PVD22128.1 - 0.34 10.9 5.3 26 4.9 0.0 4.8 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 SRCR PF00530.18 PVD22130.1 - 8e-100 327.9 25.7 9.7e-27 93.4 0.6 6.0 5 1 1 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD22130.1 - 5.4e-22 78.2 15.2 8.7e-05 23.0 0.0 5.2 4 1 1 5 5 5 5 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22130.1 - 1.7e-12 47.8 4.0 0.036 14.6 0.0 5.3 4 1 1 5 5 5 4 Hepsin, SRCR domain SRCR PF00530.18 PVD22131.1 - 1.2e-239 776.6 55.1 3.6e-30 104.4 0.4 11.1 11 0 0 11 11 11 11 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD22131.1 - 3.6e-54 181.3 33.4 1.4e-05 25.5 0.1 10.8 9 1 2 11 11 11 10 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22131.1 - 1.2e-30 106.3 9.7 0.014 15.9 0.0 10.5 10 0 0 10 10 10 8 Hepsin, SRCR domain DUF2997 PF11211.8 PVD22131.1 - 0.002 17.9 0.1 7.1 6.5 0.0 4.3 5 0 0 5 5 5 1 Protein of unknown function (DUF2997) SapB_2 PF03489.17 PVD22131.1 - 0.017 15.2 5.0 61 3.9 0.0 6.7 9 0 0 9 9 9 0 Saposin-like type B, region 2 zf_PR_Knuckle PF18445.1 PVD22131.1 - 0.15 11.9 13.6 0.71 9.7 0.0 7.1 9 0 0 9 9 9 0 PR zinc knuckle motif zf-3CxxC PF13695.6 PVD22131.1 - 0.87 10.1 4.6 0.47 10.9 0.4 2.8 4 0 0 4 4 4 0 Zinc-binding domain SRCR PF00530.18 PVD22132.1 - 0 1098.7 95.9 1.4e-27 96.1 1.1 15.5 15 0 0 15 15 15 15 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD22132.1 - 1.2e-60 202.1 53.2 0.0002 21.8 0.0 15.5 15 0 0 15 15 15 13 Scavenger receptor cysteine-rich domain Sushi PF00084.20 PVD22132.1 - 8.9e-32 109.5 53.2 2.2e-07 31.3 4.1 7.6 7 0 0 7 7 7 5 Sushi repeat (SCR repeat) HYR PF02494.16 PVD22132.1 - 2.6e-30 104.6 12.3 4.4e-15 55.8 4.5 2.8 2 0 0 2 2 2 2 HYR domain Hepsin-SRCR PF09272.10 PVD22132.1 - 8.8e-30 103.5 19.2 0.038 14.5 0.0 15.4 16 0 0 16 16 16 8 Hepsin, SRCR domain Ldl_recept_b PF00058.17 PVD22132.1 - 7.7e-21 74.3 10.9 6.4e-11 42.5 0.3 5.5 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD22132.1 - 2.9e-06 27.5 6.8 2.9e-06 27.5 6.8 7.4 7 0 0 7 7 7 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD22132.1 - 0.011 16.0 5.8 0.23 11.8 5.8 3.7 1 0 0 1 1 1 0 EGF-like domain Prefoldin_2 PF01920.20 PVD22133.1 - 4.2e-25 87.8 10.9 5.5e-25 87.4 10.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Rx_N PF18052.1 PVD22133.1 - 0.0028 17.9 7.3 0.0029 17.9 0.2 2.2 1 1 1 2 2 2 1 Rx N-terminal domain Prefoldin PF02996.17 PVD22133.1 - 0.014 15.3 12.3 0.57 10.1 12.3 2.4 1 1 0 1 1 1 0 Prefoldin subunit Syntaxin_2 PF14523.6 PVD22133.1 - 0.017 15.5 12.3 0.046 14.1 2.5 2.5 1 1 0 2 2 2 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 PVD22133.1 - 0.018 15.6 5.0 0.26 11.9 0.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 PVD22133.1 - 0.057 13.9 12.7 0.087 13.3 2.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region BORCS8 PF10167.9 PVD22133.1 - 0.1 12.5 0.7 0.1 12.5 0.7 2.2 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF1664 PF07889.12 PVD22133.1 - 0.13 12.3 10.1 0.14 12.2 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med2 PF11214.8 PVD22133.1 - 0.19 11.9 10.2 1.1 9.5 2.5 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 DHR10 PF18595.1 PVD22133.1 - 0.22 11.6 16.5 9.6 6.3 16.5 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Sulfatase_C PF14707.6 PVD22133.1 - 0.5 11.1 2.8 0.7 10.6 0.3 2.0 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase THOC7 PF05615.13 PVD22133.1 - 0.74 10.1 10.6 11 6.3 10.6 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 KxDL PF10241.9 PVD22133.1 - 1 9.7 10.5 1.2 9.5 2.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4763 PF15960.5 PVD22133.1 - 1.4 8.2 11.3 6.3 6.0 11.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) YojJ PF10372.9 PVD22133.1 - 1.6 8.9 5.0 1.1 9.4 0.5 2.4 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FlaC_arch PF05377.11 PVD22133.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 PVD22133.1 - 2 7.7 9.1 2.2 7.6 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ntox28 PF15605.6 PVD22133.1 - 2.5 8.4 8.2 9.1 6.6 1.4 2.2 1 1 1 2 2 2 0 Bacterial toxin 28 OmpH PF03938.14 PVD22133.1 - 2.8 8.3 18.3 1.1 9.6 2.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IZUMO PF15005.6 PVD22133.1 - 3.8 8.0 7.6 15 6.1 6.0 1.9 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF737 PF05300.11 PVD22133.1 - 5.7 7.2 13.1 11 6.4 13.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Fib_alpha PF08702.10 PVD22133.1 - 7.7 6.7 10.4 2.8 8.1 2.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-RING_2 PF13639.6 PVD22134.1 - 4.6e-11 42.9 3.3 1.6e-10 41.1 3.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PVD22134.1 - 7.6e-11 41.6 4.8 2.9e-10 39.7 4.8 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PVD22134.1 - 9.2e-09 35.5 0.7 2.9e-08 33.9 0.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PVD22134.1 - 2.1e-07 30.6 2.8 5.9e-07 29.2 2.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22134.1 - 3e-07 30.2 2.9 3e-07 30.2 2.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22134.1 - 2.4e-05 24.3 4.0 7.2e-05 22.7 4.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22134.1 - 2.6e-05 24.1 1.2 2.6e-05 24.1 1.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PVD22134.1 - 0.0011 18.5 0.8 0.0027 17.3 0.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PVD22134.1 - 0.017 15.0 2.6 0.042 13.7 2.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD22134.1 - 0.018 15.1 3.7 0.074 13.1 3.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 PVD22134.1 - 0.024 15.0 0.9 0.072 13.4 0.9 1.9 1 0 0 1 1 1 0 RING-like domain Aldolase_II PF00596.21 PVD22134.1 - 0.13 12.2 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Syntaxin-6_N PF09177.11 PVD22135.1 - 7.2e-18 65.0 8.6 8.2e-18 64.8 2.3 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 PVD22135.1 - 1.9e-11 43.8 2.9 1.9e-11 43.8 2.9 2.1 2 0 0 2 2 2 1 SNARE domain APG17 PF04108.12 PVD22135.1 - 0.006 15.8 2.7 0.006 15.8 2.7 2.2 1 1 1 2 2 2 1 Autophagy protein Apg17 UPF0184 PF03670.13 PVD22135.1 - 0.0096 16.3 1.2 0.0096 16.3 1.2 3.3 2 2 2 4 4 4 1 Uncharacterised protein family (UPF0184) PBP1_TM PF14812.6 PVD22135.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_EPC_I2-L1 PF12575.8 PVD22135.1 - 0.025 14.8 1.3 0.43 10.8 0.4 2.3 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 m04gp34like PF12216.8 PVD22135.1 - 0.027 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein Use1 PF09753.9 PVD22135.1 - 0.037 13.8 8.9 0.058 13.1 8.8 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Pex24p PF06398.11 PVD22135.1 - 0.041 12.9 0.6 0.057 12.4 0.2 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Prominin PF05478.11 PVD22135.1 - 0.059 11.3 4.8 0.091 10.7 4.8 1.4 1 1 0 1 1 1 0 Prominin DUF5113 PF17140.4 PVD22135.1 - 0.11 12.3 1.8 0.43 10.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Orf78 PF06024.12 PVD22135.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.3 2 1 0 2 2 2 0 Orf78 (ac78) FliD_C PF07195.12 PVD22135.1 - 0.3 10.5 8.1 1.1 8.7 8.1 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Spectrin PF00435.21 PVD22135.1 - 0.63 10.6 8.5 1.8 9.1 0.7 3.1 1 1 1 3 3 3 0 Spectrin repeat DUF745 PF05335.13 PVD22135.1 - 0.9 9.2 3.7 2.4 7.9 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TBCA PF02970.16 PVD22135.1 - 1.2 9.5 7.6 36 4.8 0.1 3.0 2 1 0 2 2 2 0 Tubulin binding cofactor A DUF5383 PF17355.2 PVD22135.1 - 2 8.8 7.1 0.42 11.0 0.2 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5383) Exonuc_VII_L PF02601.15 PVD22135.1 - 8.5 5.8 9.2 55 3.2 9.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit GTP_EFTU PF00009.27 PVD22136.1 - 2.5e-25 89.1 0.6 3.9e-25 88.5 0.6 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PVD22136.1 - 4e-07 30.3 0.2 9.6e-07 29.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PVD22136.1 - 1.7e-06 28.1 0.1 3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PVD22136.1 - 0.00046 19.7 0.4 0.0018 17.8 0.4 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 PVD22136.1 - 0.0031 17.1 0.5 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PVD22136.1 - 0.049 13.4 0.4 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 PVD22136.1 - 0.083 12.7 0.7 4.5 7.0 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Sulfatase PF00884.23 PVD22137.1 - 3.9e-53 180.8 0.6 3.3e-50 171.2 0.6 2.2 1 1 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 PVD22137.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 PVD22137.1 - 0.027 15.2 0.2 0.1 13.4 0.2 1.9 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF5136 PF17199.4 PVD22138.1 - 0.087 12.5 0.4 0.22 11.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) TPR_2 PF07719.17 PVD22140.1 - 2.9e-25 86.3 22.3 0.00017 21.4 0.5 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22140.1 - 2.6e-23 80.8 25.3 4.3e-06 26.3 0.3 9.4 11 1 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22140.1 - 8.9e-19 66.9 9.3 0.0064 16.2 0.1 9.5 8 3 3 11 11 11 7 TPR repeat TPR_16 PF13432.6 PVD22140.1 - 4.4e-17 62.4 2.2 0.0025 18.4 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD22140.1 - 8.7e-10 38.8 17.4 0.38 11.1 0.0 6.7 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 PVD22140.1 - 2.1e-09 37.4 12.2 0.036 14.2 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22140.1 - 3.8e-08 32.9 14.5 0.5 10.7 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD22140.1 - 1e-07 32.1 11.7 0.29 12.0 0.0 8.0 6 3 5 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD22140.1 - 3e-06 27.2 7.6 1.3 9.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22140.1 - 1.7e-05 25.2 19.8 0.021 15.3 0.1 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 PVD22140.1 - 2.1e-05 23.7 2.0 0.036 13.0 0.1 4.3 1 1 4 5 5 5 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 PVD22140.1 - 0.00052 20.2 21.8 0.00078 19.6 3.8 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF1033 PF06279.11 PVD22140.1 - 0.021 15.0 0.5 0.061 13.5 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) TPR_7 PF13176.6 PVD22140.1 - 0.027 14.5 8.5 12 6.2 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Com_YlbF PF06133.11 PVD22140.1 - 0.092 13.4 0.0 0.092 13.4 0.0 3.1 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA TPR_10 PF13374.6 PVD22140.1 - 0.13 12.2 0.2 9.4 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Pal1 PF08316.11 PVD22140.1 - 0.19 12.5 2.1 0.5 11.1 2.1 1.7 1 0 0 1 1 1 0 Pal1 cell morphology protein CARD PF00619.21 PVD22141.1 - 6.1e-05 23.0 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 Caspase recruitment domain Hormone_recep PF00104.30 PVD22142.1 - 9.1e-16 58.1 0.6 1.7e-15 57.1 0.6 1.4 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor WD40 PF00400.32 PVD22145.1 - 1.5e-38 130.1 16.7 2.4e-06 28.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 PVD22145.1 - 2.1e-15 56.0 2.0 4.2e-15 55.0 2.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 PVD22145.1 - 1e-07 32.2 0.0 0.29 11.5 0.0 4.9 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD22145.1 - 0.0015 17.5 0.2 4.6 6.1 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PVD22145.1 - 0.045 13.1 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain FAM25 PF15825.5 PVD22145.1 - 0.44 10.9 8.4 0.62 10.4 0.2 2.7 3 0 0 3 3 3 0 FAM25 family STAT_int PF02865.17 PVD22146.1 - 7.4e-12 45.8 2.0 1.1e-11 45.2 0.6 2.1 1 1 1 2 2 2 1 STAT protein, protein interaction domain STAT_bind PF02864.15 PVD22146.1 - 0.0025 18.4 0.1 0.0025 18.4 0.1 2.3 3 0 0 3 3 3 1 STAT protein, DNA binding domain SMBP PF16785.5 PVD22146.1 - 0.04 14.1 0.8 0.09 13.0 0.6 1.7 1 1 0 1 1 1 0 Small metal-binding protein SH2 PF00017.24 PVD22146.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 SH2 domain FBPase PF00316.20 PVD22146.1 - 0.097 12.1 0.1 0.3 10.5 0.1 1.7 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain STAT_bind PF02864.15 PVD22147.1 - 2e-05 25.1 0.2 3.6e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.24 PVD22147.1 - 0.028 14.5 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 SH2 domain Herpes_UL69 PF05459.12 PVD22147.1 - 0.031 13.6 0.1 9.8 5.5 0.1 2.6 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family FAM176 PF14851.6 PVD22148.1 - 0.16 11.6 0.6 0.19 11.4 0.6 1.1 1 0 0 1 1 1 0 FAM176 family Ank_2 PF12796.7 PVD22151.1 - 1.8e-16 60.5 1.1 2.3e-10 40.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD22151.1 - 4e-10 39.7 2.0 2.4e-06 27.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD22151.1 - 2.7e-08 33.4 0.4 0.0026 18.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD22151.1 - 2.4e-07 30.9 0.4 0.00065 20.0 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD22151.1 - 2.3e-06 28.1 1.4 0.0056 17.2 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ADP_ribosyl_GH PF03747.14 PVD22152.1 - 2.9e-23 83.0 0.0 3.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PAC1 PF16094.5 PVD22152.1 - 0.17 11.0 0.1 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 F-box-like PF12937.7 PVD22153.1 - 5.8e-13 48.5 1.2 1.2e-12 47.5 1.2 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 PVD22153.1 - 8.4e-12 45.4 7.1 0.00015 22.5 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box PF00646.33 PVD22153.1 - 7.9e-09 35.2 2.7 2.6e-08 33.5 2.7 2.0 1 0 0 1 1 1 1 F-box domain Glu_cyclase_2 PF05096.12 PVD22153.1 - 0.097 12.1 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Glutamine cyclotransferase F-box_4 PF15966.5 PVD22153.1 - 0.19 11.6 1.9 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 F-box WD40 PF00400.32 PVD22154.1 - 3.7e-19 68.7 15.3 6.4e-06 26.8 0.0 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD22154.1 - 0.0033 17.7 0.1 8.1 6.8 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 PVD22154.1 - 0.0058 16.5 0.3 0.017 15.0 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PVD22154.1 - 0.019 14.9 1.5 0.031 14.2 0.3 2.0 2 0 0 2 2 2 0 F-box-like Amidoligase_2 PF12224.8 PVD22155.1 - 0.014 15.1 0.2 0.017 14.8 0.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme Ribosomal_S21 PF01165.20 PVD22155.1 - 0.032 14.0 0.5 0.043 13.5 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S21 MHC2-interact PF09307.10 PVD22158.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF4407 PF14362.6 PVD22159.1 - 5.1 6.4 4.7 12 5.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1223 PF06764.11 PVD22160.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) RVT_1 PF00078.27 PVD22166.1 - 5.8e-39 133.9 0.0 9.6e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P22_AR_N PF10547.9 PVD22166.1 - 0.08 13.3 0.1 7.1 7.0 0.0 2.5 2 0 0 2 2 2 0 P22_AR N-terminal domain Exo_endo_phos_2 PF14529.6 PVD22167.1 - 1.3e-05 25.0 0.2 0.0026 17.6 0.0 3.0 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase MutS_IV PF05190.18 PVD22167.1 - 0.017 15.4 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV DUF1932 PF09130.11 PVD22167.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Cys_rich_KTR PF14205.6 PVD22167.1 - 0.79 9.6 2.4 2.5 8.0 0.0 2.5 3 0 0 3 3 3 0 Cysteine-rich KTR Orthopox_A36R PF05950.11 PVD22169.1 - 0.022 14.9 0.2 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Ctr PF04145.15 PVD22169.1 - 0.079 13.6 0.0 0.68 10.6 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Prenyltrans PF00432.21 PVD22171.1 - 1.4e-62 207.1 7.0 4.4e-16 58.3 0.2 4.2 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 PVD22171.1 - 0.00012 21.3 0.1 0.00025 20.2 0.0 1.5 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 PVD22171.1 - 0.0032 16.6 0.0 0.77 8.8 0.0 2.8 1 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 PVD22171.1 - 0.0066 15.5 0.0 0.26 10.3 0.0 2.2 1 1 1 2 2 2 1 A-macroglobulin TED domain MFS_1 PF07690.16 PVD22172.1 - 2.1e-39 135.4 28.3 1.4e-32 113.0 13.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD22172.1 - 4.4e-07 29.5 3.0 4.4e-07 29.5 3.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 PVD22172.1 - 2.3e-06 26.2 1.0 4.7e-06 25.2 0.2 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD22175.1 - 5.2e-26 91.4 8.6 6.3e-26 91.1 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 PVD22175.1 - 0.0007 18.0 0.2 0.0014 17.0 0.0 1.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 PVD22175.1 - 0.0034 16.3 11.0 0.056 12.3 3.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD22175.1 - 0.31 9.5 13.5 0.014 14.0 4.7 2.2 1 1 0 2 2 2 0 MFS/sugar transport protein Ribosomal_S7 PF00177.21 PVD22176.1 - 5.4e-24 84.5 0.3 6.3e-24 84.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DEAD PF00270.29 PVD22177.1 - 8.8e-28 97.2 0.1 7.4e-22 77.9 0.1 2.7 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD22177.1 - 1.5e-22 80.0 0.0 7.9e-22 77.7 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PVD22177.1 - 1.7e-17 63.4 0.1 3.7e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PVD22177.1 - 1.9e-08 34.5 0.1 3.5e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PVD22177.1 - 0.011 14.9 0.0 0.03 13.5 0.0 1.7 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HNOBA PF07701.14 PVD22177.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.5 1 1 0 1 1 1 0 Heme NO binding associated TauD PF02668.16 PVD22178.1 - 6.3e-37 127.8 0.0 9.1e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family eIF2A PF08662.11 PVD22178.1 - 0.006 16.5 0.1 0.0099 15.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A 7tm_1 PF00001.21 PVD22179.1 - 6.4e-11 42.1 0.2 9.4e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD22179.1 - 0.007 16.1 0.4 0.0095 15.7 0.4 1.1 1 0 0 1 1 1 1 Olfactory receptor DUF1772 PF08592.11 PVD22179.1 - 0.65 10.3 3.2 0.6 10.4 1.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2749 PF10907.8 PVD22180.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Glyco_hydro_20 PF00728.22 PVD22181.1 - 2.4e-61 208.1 4.5 3.6e-56 191.1 1.0 3.3 2 1 1 3 3 3 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PVD22181.1 - 4.3e-11 43.6 0.0 1.1e-10 42.3 0.0 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PVD22181.1 - 4.1e-06 27.6 0.0 7.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4073 PF13285.6 PVD22181.1 - 0.058 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Ldl_recept_b PF00058.17 PVD22183.1 - 8.8e-37 125.3 3.4 2.1e-12 47.3 0.1 7.2 8 0 0 8 8 8 4 Low-density lipoprotein receptor repeat class B SRCR PF00530.18 PVD22183.1 - 2.2e-36 124.3 9.4 1.2e-27 96.3 3.6 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF5050 PF16472.5 PVD22183.1 - 1e-12 47.9 0.1 1.6e-07 30.8 0.1 3.9 2 2 1 3 3 3 2 Domain of unknown function (DUF5050) SGL PF08450.12 PVD22183.1 - 2.7e-09 37.0 0.5 0.0026 17.4 0.1 2.7 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 PVD22183.1 - 1.8e-05 24.2 0.1 0.0067 15.7 0.0 3.2 2 2 0 3 3 3 2 Lactonase, 7-bladed beta-propeller SRCR_2 PF15494.6 PVD22183.1 - 0.00012 22.6 0.7 0.00031 21.2 0.7 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Arylesterase PF01731.20 PVD22183.1 - 0.006 16.8 0.0 0.37 11.0 0.0 3.1 1 1 1 2 2 2 1 Arylesterase SRCR PF00530.18 PVD22184.1 - 3.3e-36 123.8 8.2 3.4e-27 94.9 2.3 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 PVD22184.1 - 3.9e-34 116.8 4.4 1.1e-11 45.0 0.3 6.1 6 0 0 6 6 6 4 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 PVD22184.1 - 1.1e-13 51.1 0.5 5.3e-08 32.4 0.0 3.1 2 2 0 2 2 2 2 Domain of unknown function (DUF5050) SGL PF08450.12 PVD22184.1 - 5.9e-08 32.6 2.1 0.0074 15.9 0.3 2.6 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region SRCR_2 PF15494.6 PVD22184.1 - 1.3e-05 25.7 1.2 3.9e-05 24.1 1.2 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Lactonase PF10282.9 PVD22184.1 - 4e-05 23.0 3.1 0.018 14.3 0.0 3.4 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 PVD22184.1 - 0.0085 16.3 0.1 0.094 12.9 0.0 2.8 2 1 1 3 3 3 1 Arylesterase SRCR PF00530.18 PVD22185.1 - 3.1e-52 175.2 14.9 2.8e-27 95.1 5.0 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 PVD22185.1 - 4.2e-21 75.1 3.2 3.7e-05 24.1 0.0 7.3 7 1 1 8 8 8 5 Low-density lipoprotein receptor repeat class B SRCR_2 PF15494.6 PVD22185.1 - 8.3e-11 42.3 2.3 0.00011 22.7 0.8 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF5050 PF16472.5 PVD22185.1 - 1.5e-08 34.2 0.0 0.00046 19.5 0.0 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF5050) SGL PF08450.12 PVD22185.1 - 1.5e-06 28.0 0.1 0.15 11.6 0.0 3.8 3 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Hepsin-SRCR PF09272.10 PVD22185.1 - 0.0058 17.1 0.3 6.4 7.3 0.1 2.6 2 0 0 2 2 2 2 Hepsin, SRCR domain Pkinase PF00069.25 PVD22187.1 - 2e-54 184.7 0.0 2.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22187.1 - 4.4e-26 91.7 0.0 5.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD22187.1 - 3.1e-06 26.3 0.0 6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD22187.1 - 6.4e-06 26.3 1.2 0.00018 21.5 0.5 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD22187.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD22187.1 - 0.00062 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PVD22187.1 - 0.00075 19.2 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 PVD22187.1 - 0.02 13.9 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 PVD22187.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 PVD22188.1 - 1.1e-56 192.2 0.0 1.6e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22188.1 - 5.9e-29 101.1 0.0 8.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lectin_C PF00059.21 PVD22188.1 - 5e-19 69.0 0.5 6.5e-08 33.3 0.1 3.0 2 1 0 2 2 2 2 Lectin C-type domain Pkinase_fungal PF17667.1 PVD22188.1 - 9.6e-07 27.9 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD22188.1 - 1.6e-05 24.4 0.0 4.4e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD22188.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PAN_3 PF08277.12 PVD22188.1 - 0.11 12.4 3.5 5.2 7.0 0.2 2.6 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 PVD22188.1 - 0.25 11.3 4.6 5.6 6.9 0.7 3.0 2 0 0 2 2 2 0 PAN domain SRCR PF00530.18 PVD22189.1 - 4.7e-55 184.3 12.4 7.9e-29 100.1 1.3 3.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 PVD22189.1 - 1.4e-29 102.3 7.0 1.6e-07 31.7 0.0 7.4 7 0 0 7 7 7 5 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 PVD22189.1 - 8.9e-14 51.4 0.1 4.2e-06 26.2 0.1 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF5050) SRCR_2 PF15494.6 PVD22189.1 - 2e-10 41.1 7.1 3.4e-05 24.3 0.1 2.7 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22189.1 - 0.0071 16.9 0.1 0.56 10.8 0.0 2.6 2 0 0 2 2 2 1 Hepsin, SRCR domain DUF5122 PF17164.4 PVD22189.1 - 0.14 12.5 7.0 2.9 8.2 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller SDA1 PF05285.12 PVD22190.1 - 0.007 15.8 8.0 0.0074 15.8 8.0 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 PVD22190.1 - 0.008 16.3 7.5 0.0092 16.1 7.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 PVD22190.1 - 0.023 12.9 7.5 0.023 12.9 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 PVD22190.1 - 0.036 12.4 8.4 0.033 12.5 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 PVD22190.1 - 0.047 12.1 10.0 0.054 11.9 10.0 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 PVD22190.1 - 0.061 11.4 12.8 0.059 11.5 12.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 PVD22190.1 - 0.2 9.7 1.7 0.17 9.9 1.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SMN PF06003.12 PVD22190.1 - 0.36 10.0 7.9 0.43 9.8 7.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Radial_spoke PF04712.12 PVD22190.1 - 0.38 9.7 5.7 0.38 9.7 5.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein XAP5 PF04921.14 PVD22190.1 - 0.52 10.1 5.4 0.61 9.9 5.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator eIF3_subunit PF08597.10 PVD22190.1 - 0.62 9.9 13.4 0.71 9.7 13.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Lin-8 PF03353.15 PVD22190.1 - 0.95 9.0 5.6 1.1 8.8 5.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CobT PF06213.12 PVD22190.1 - 1.1 8.5 10.6 1.3 8.4 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 PVD22190.1 - 1.5 8.8 7.5 2 8.4 7.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 PVD22190.1 - 1.6 8.4 7.8 2.6 7.7 7.8 1.4 1 0 0 1 1 1 0 FAM176 family Homeodomain PF00046.29 PVD22191.1 - 4.7e-10 39.2 0.5 8.2e-10 38.4 0.3 1.5 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 PVD22193.1 - 6.6e-12 45.1 0.8 1.3e-11 44.1 0.8 1.5 1 0 0 1 1 1 1 Homeodomain Choline_transpo PF04515.12 PVD22194.1 - 3.6e-92 309.1 33.4 3.6e-92 309.1 33.4 3.1 3 0 0 3 3 3 1 Plasma-membrane choline transporter Hol_Tox PF16935.5 PVD22194.1 - 0.25 11.4 0.1 0.25 11.4 0.1 4.2 4 1 0 4 4 4 0 Putative Holin-like Toxin (Hol-Tox) Choline_transpo PF04515.12 PVD22195.1 - 4.9e-88 295.5 15.9 4.9e-88 295.5 15.9 3.9 3 2 2 5 5 5 2 Plasma-membrane choline transporter MAM PF00629.23 PVD22196.1 - 3.2e-17 62.9 0.1 1.1e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD22196.1 - 1.8e-06 28.1 12.5 1.8e-06 28.1 12.5 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF5564 PF17719.1 PVD22196.1 - 0.0011 19.1 11.3 0.0032 17.6 11.3 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5564) MoeA_C PF03454.15 PVD22196.1 - 0.079 13.1 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) PH PF00169.29 PVD22197.1 - 1.7e-06 28.4 0.0 3.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 PVD22197.1 - 0.059 13.2 0.2 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 PH domain KDZ PF18758.1 PVD22198.1 - 2.3e-28 99.3 0.0 2.8e-18 66.4 0.0 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 PVD22198.1 - 6.9e-11 42.2 0.0 2.5e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 PVD22198.1 - 7.8e-10 38.9 0.3 2.9e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases dsrm PF00035.26 PVD22200.1 - 4.3e-09 37.0 0.0 0.015 16.0 0.0 3.7 3 0 0 3 3 3 2 Double-stranded RNA binding motif C1q PF00386.21 PVD22201.1 - 7.2e-10 39.2 0.0 9.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD22201.1 - 0.1 12.5 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 BclA C-terminal domain Actin PF00022.19 PVD22202.1 - 1.2e-41 142.7 0.0 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Actin PhyH PF05721.13 PVD22202.1 - 1.3e-21 77.8 0.0 5.4e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) BRICHOS PF04089.14 PVD22202.1 - 0.00075 19.7 0.0 0.0038 17.4 0.0 2.3 1 1 0 1 1 1 1 BRICHOS domain DUF3040 PF11239.8 PVD22202.1 - 0.066 13.5 0.3 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PilM_2 PF11104.8 PVD22202.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PhyH PF05721.13 PVD22203.1 - 1.1e-49 169.6 0.1 1.3e-49 169.3 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NIDO PF06119.14 PVD22204.1 - 3.7e-24 85.5 0.1 1.1e-23 84.0 0.1 1.9 1 0 0 1 1 1 1 Nidogen-like AMOP PF03782.17 PVD22204.1 - 1e-21 77.6 1.1 2.2e-21 76.5 1.1 1.5 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 PVD22204.1 - 1.9e-18 67.2 0.8 5.3e-18 65.8 0.8 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain Sushi PF00084.20 PVD22204.1 - 2.5e-07 31.2 0.1 7.4e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TIG PF01833.24 PVD22204.1 - 0.00017 21.6 0.8 0.00017 21.6 0.8 3.3 4 0 0 4 4 4 1 IPT/TIG domain Baculo_11_kDa PF06143.11 PVD22206.1 - 0.073 12.6 2.7 0.1 12.2 2.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family TM_helix PF05552.12 PVD22206.1 - 7.3 6.6 10.4 76 3.4 10.2 2.1 1 1 0 1 1 1 0 Conserved TM helix SSF PF00474.17 PVD22207.1 - 4e-18 65.5 21.8 1.4e-13 50.5 4.5 2.4 3 0 0 3 3 3 2 Sodium:solute symporter family Chs7 PF12271.8 PVD22207.1 - 3.6 6.9 9.6 0.081 12.3 2.6 1.8 2 0 0 2 2 2 0 Chitin synthase export chaperone GRP PF07172.11 PVD22208.1 - 0.0091 16.7 0.4 0.0091 16.7 0.4 2.6 2 1 0 2 2 2 1 Glycine rich protein family TMIE PF16038.5 PVD22208.1 - 0.25 11.2 3.9 0.39 10.6 3.9 1.1 1 0 0 1 1 1 0 TMIE protein Shisa PF13908.6 PVD22208.1 - 0.82 9.9 0.0 0.82 9.9 0.0 2.3 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator TPR_12 PF13424.6 PVD22209.1 - 4.1e-14 52.6 2.7 2.5e-08 34.1 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22209.1 - 2.7e-07 30.3 0.5 0.059 13.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD22209.1 - 1.6e-06 27.8 7.3 0.0073 16.3 0.2 4.5 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD22209.1 - 3.1e-06 26.9 0.6 0.097 12.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22209.1 - 2.5e-05 24.0 4.7 0.5 10.5 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22209.1 - 3e-05 23.6 5.4 0.0093 15.8 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22209.1 - 5.5e-05 23.7 0.1 0.031 14.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD22209.1 - 0.00043 20.9 1.1 0.31 12.0 0.0 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD22209.1 - 0.0006 20.3 0.9 5 8.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PhoU_div PF01865.16 PVD22209.1 - 0.032 13.6 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF47 Daxx PF03344.15 PVD22209.1 - 0.11 12.6 0.1 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain IKKbetaNEMObind PF12179.8 PVD22209.1 - 0.13 12.4 0.0 0.52 10.4 0.0 2.1 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DnaJ PF00226.31 PVD22210.1 - 0.002 18.2 30.3 0.15 12.2 0.4 6.4 4 3 2 6 6 6 3 DnaJ domain DUF5033 PF16436.5 PVD22210.1 - 0.0027 17.7 0.5 17 5.3 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5033) PI3K_p85B PF02192.16 PVD22210.1 - 0.018 14.8 0.5 26 4.6 0.0 3.7 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain TPR_11 PF13414.6 PVD22210.1 - 1.1 9.0 9.2 13 5.5 0.1 4.7 5 0 0 5 5 5 0 TPR repeat CBM49 PF09478.10 PVD22210.1 - 2.4 8.5 4.7 42 4.5 0.0 3.5 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 SMBP PF16785.5 PVD22210.1 - 2.6 8.3 5.4 2.5 8.4 0.3 3.4 3 0 0 3 3 3 0 Small metal-binding protein StbA PF06406.11 PVD22210.1 - 8 5.6 7.8 13 4.9 0.3 3.3 3 0 0 3 3 3 0 StbA protein DnaJ PF00226.31 PVD22211.1 - 0.0033 17.5 5.7 0.0062 16.6 0.2 3.1 1 1 1 2 2 2 1 DnaJ domain TPR_12 PF13424.6 PVD22211.1 - 0.075 13.3 11.0 0.13 12.6 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat YlaC PF10777.9 PVD22211.1 - 0.08 12.8 3.1 0.19 11.6 3.1 1.6 1 1 0 1 1 1 0 Inner membrane protein YlaC Rsa3 PF14615.6 PVD22211.1 - 0.12 12.0 2.5 1.7 8.2 0.1 3.3 3 1 1 4 4 4 0 Ribosome-assembly protein 3 TPR_16 PF13432.6 PVD22211.1 - 0.25 12.0 7.1 0.78 10.4 0.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 PVD22212.1 - 0.0019 18.3 5.3 0.0022 18.1 0.6 3.0 1 1 1 2 2 2 1 DnaJ domain Amidohydro_2 PF04909.14 PVD22213.1 - 2.7e-16 60.2 0.0 5.8e-16 59.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase SSF PF00474.17 PVD22214.1 - 2.9e-119 398.5 21.4 5.1e-119 397.8 21.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Bacillus_PapR PF05968.11 PVD22215.1 - 0.72 9.8 14.9 0.92 9.4 0.8 3.3 3 0 0 3 3 3 0 Bacillus PapR protein BK_channel_a PF03493.18 PVD22217.1 - 2.3e-31 107.9 0.0 7.3e-31 106.3 0.0 1.9 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PVD22217.1 - 4.7e-11 42.5 2.5 1.3e-10 41.0 2.5 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PVD22217.1 - 5.8e-05 22.4 11.1 0.00012 21.4 11.1 1.5 1 0 0 1 1 1 1 Ion transport protein Fam20C PF06702.12 PVD22218.1 - 5.2e-77 258.5 0.2 6.9e-77 258.2 0.2 1.1 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 PVD22218.1 - 0.0014 18.5 0.1 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Fam20C PF06702.12 PVD22219.1 - 4.8e-49 167.1 0.4 3.8e-33 115.1 0.0 2.1 1 1 1 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 PVD22219.1 - 0.077 12.8 0.5 0.11 12.3 0.5 1.3 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Fam20C PF06702.12 PVD22220.1 - 3.5e-31 108.7 0.3 5.4e-31 108.1 0.1 1.4 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 PVD22220.1 - 0.0041 17.0 0.8 0.0062 16.4 0.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HipA_C PF07804.12 PVD22220.1 - 0.074 12.7 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 HipA-like C-terminal domain Fam20C PF06702.12 PVD22221.1 - 4.1e-64 216.4 0.2 6.6e-64 215.7 0.2 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 PVD22221.1 - 0.01 15.7 1.5 0.024 14.4 1.5 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase FAM198 PF15051.6 PVD22221.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 FAM198 protein Proteasom_PSMB PF10508.9 PVD22222.1 - 5.4e-129 430.9 1.1 6.2e-129 430.7 1.1 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Retrotran_gag_2 PF14223.6 PVD22222.1 - 2.1e-05 24.2 1.1 0.05 13.3 0.0 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type RICTOR_V PF14668.6 PVD22222.1 - 0.00039 20.6 0.0 4.4 7.6 0.0 4.1 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 PVD22222.1 - 0.011 15.5 1.6 5.4 6.9 0.1 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain DUF3631 PF12307.8 PVD22222.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) RTTN_N PF14726.6 PVD22222.1 - 0.16 12.8 1.4 0.98 10.3 0.1 3.0 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning DUF4455 PF14643.6 PVD22223.1 - 4.2e-146 487.3 38.3 4.2e-146 487.3 38.3 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 PVD22223.1 - 4.2e-56 190.0 14.9 4.2e-56 190.0 14.9 6.3 6 2 1 7 7 7 1 Domain of unknown function (DUF4456) NFRKB_winged PF14465.6 PVD22223.1 - 0.02 15.1 0.0 0.69 10.1 0.0 3.6 2 0 0 2 2 2 0 NFRKB Winged Helix-like zf-AD PF07776.15 PVD22223.1 - 0.21 11.8 3.6 0.34 11.2 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Lge1 PF11488.8 PVD22223.1 - 0.75 10.0 11.7 6.9 6.9 0.0 5.6 5 0 0 5 5 5 0 Transcriptional regulatory protein LGE1 Lectin_N PF03954.14 PVD22223.1 - 3.9 7.2 13.0 11 5.8 0.1 5.1 5 0 0 5 5 5 0 Hepatic lectin, N-terminal domain Coq4 PF05019.13 PVD22224.1 - 8e-32 110.4 0.0 9e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Torsin PF06309.11 PVD22225.1 - 1.5e-06 28.3 0.0 5.3e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Torsin DUF4647 PF15504.6 PVD22226.1 - 0.052 12.6 15.0 0.012 14.7 7.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4647) BAR PF03114.18 PVD22227.1 - 1.5e-64 217.9 9.1 2.3e-64 217.3 9.1 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 PVD22227.1 - 1.7e-10 40.5 3.9 1.7e-10 40.5 3.9 1.6 1 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_9 PF14604.6 PVD22227.1 - 3.7e-10 39.5 0.0 6.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 PVD22227.1 - 1.1e-08 35.0 6.3 1.6e-08 34.6 6.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family SH3_1 PF00018.28 PVD22227.1 - 6.2e-07 28.9 0.1 2e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD22227.1 - 2.1e-06 27.3 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 PVD22227.1 - 0.0031 16.9 0.6 0.0031 16.9 0.6 1.6 2 0 0 2 2 2 1 IRSp53/MIM homology domain T6PP_N PF18572.1 PVD22227.1 - 0.36 10.7 4.4 0.23 11.3 1.4 2.0 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain 7tm_1 PF00001.21 PVD22228.1 - 2.2e-26 92.8 8.4 3e-26 92.3 8.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Yip1 PF04893.17 PVD22228.1 - 0.31 10.7 17.2 1.7 8.3 14.4 2.4 1 1 1 2 2 2 0 Yip1 domain 7tm_1 PF00001.21 PVD22229.1 - 1.3e-32 113.2 0.5 1.7e-32 112.8 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LapA_dom PF06305.11 PVD22229.1 - 1.3 8.9 12.3 14 5.6 0.1 4.7 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain DUF2070 PF09843.9 PVD22229.1 - 1.3 7.2 9.6 2.3 6.4 9.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_1 PF00001.21 PVD22230.1 - 3.3e-28 98.7 6.2 4.7e-28 98.2 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Yip1 PF04893.17 PVD22230.1 - 0.074 12.8 16.1 0.98 9.1 9.1 2.3 1 1 1 2 2 2 0 Yip1 domain DUF4199 PF13858.6 PVD22230.1 - 0.17 12.3 9.4 0.28 11.6 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) VWA PF00092.28 PVD22231.1 - 4.1e-13 49.9 0.1 7.9e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain IQ PF00612.27 PVD22231.1 - 0.00093 18.8 1.0 0.0023 17.6 1.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif VWA_2 PF13519.6 PVD22231.1 - 0.0065 17.1 0.2 0.031 14.9 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain HU-CCDC81_bac_2 PF18175.1 PVD22232.1 - 0.041 13.7 0.6 0.25 11.2 0.7 1.9 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CHAT PF12770.7 PVD22233.1 - 6.1e-27 94.8 0.2 1.3e-26 93.7 0.2 1.5 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 PVD22234.1 - 1.9e-25 86.9 15.9 0.00027 20.8 0.1 9.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 PVD22234.1 - 7.6e-22 77.4 22.5 8.9e-08 32.3 2.5 7.1 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22234.1 - 1.9e-21 74.9 14.0 0.0019 17.9 0.1 8.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22234.1 - 2.8e-16 58.2 16.0 0.0028 17.6 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22234.1 - 3.8e-16 57.9 22.4 0.0086 16.2 0.3 10.6 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22234.1 - 3.8e-15 55.3 2.6 0.00015 21.3 0.0 5.0 4 1 0 4 4 4 3 TPR repeat CHAT PF12770.7 PVD22234.1 - 3.9e-09 36.4 0.1 7.6e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 CHAT domain ANAPC3 PF12895.7 PVD22234.1 - 6e-09 36.0 12.2 0.00011 22.4 0.3 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD22234.1 - 1.8e-08 34.5 9.9 0.26 12.2 0.1 7.7 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD22234.1 - 7.8e-08 32.0 19.7 0.042 13.7 0.2 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22234.1 - 4.2e-07 30.5 5.0 2.2 9.0 0.2 5.5 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD22234.1 - 9.7e-06 25.6 1.2 0.00059 19.9 0.2 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD22234.1 - 0.00021 20.8 3.1 0.027 13.9 0.0 3.2 2 1 1 3 3 3 1 Coatomer epsilon subunit DUF5588 PF17826.1 PVD22234.1 - 0.00032 19.7 1.1 0.12 11.2 0.7 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5588) MIT PF04212.18 PVD22234.1 - 0.00071 19.6 4.4 17 5.6 0.1 5.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 PVD22234.1 - 0.00083 18.8 25.7 0.0015 18.0 0.4 4.1 4 2 0 4 4 4 2 MalT-like TPR region TPR_6 PF13174.6 PVD22234.1 - 0.002 18.6 15.4 3.2 8.6 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD22234.1 - 0.0026 17.8 3.2 12 6.1 0.0 4.9 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 PVD22234.1 - 0.0067 16.2 10.9 0.061 13.0 1.1 4.5 3 2 0 3 3 3 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 PVD22234.1 - 0.018 15.4 9.0 46 4.7 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 PVD22234.1 - 0.032 13.4 5.8 3.3 6.8 0.2 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 PVD22234.1 - 0.099 12.9 4.1 53 4.4 0.0 4.9 5 0 0 5 5 4 0 PPR repeat DUF2225 PF09986.9 PVD22234.1 - 0.1 12.3 5.1 0.045 13.5 0.7 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PSDC PF12588.8 PVD22234.1 - 0.11 12.5 0.5 4.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Phophatidylserine decarboxylase BTAD PF03704.17 PVD22234.1 - 0.24 11.8 9.6 2.2 8.7 0.1 4.5 4 2 1 5 5 5 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 PVD22234.1 - 0.64 10.6 22.2 0.2 12.2 0.4 6.0 5 2 2 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD22234.1 - 0.9 9.2 6.7 1.8 8.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 PVD22234.1 - 7 6.8 9.0 2.4 8.3 1.6 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Kelch_4 PF13418.6 PVD22235.1 - 4e-50 167.6 35.1 3.4e-11 43.0 0.1 12.8 12 0 0 12 12 12 9 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD22235.1 - 5.7e-45 150.7 39.9 5.9e-06 26.2 0.2 13.2 12 0 0 12 12 12 11 Kelch motif Kelch_6 PF13964.6 PVD22235.1 - 7.9e-41 137.1 41.2 7.3e-08 32.4 0.1 12.8 12 0 0 12 12 12 10 Kelch motif Kelch_3 PF13415.6 PVD22235.1 - 3.9e-36 122.7 50.7 6.1e-06 26.4 0.0 13.0 14 0 0 14 14 14 8 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD22235.1 - 4.2e-25 86.7 36.7 0.00012 21.9 0.6 11.7 11 0 0 11 11 11 7 Kelch motif Kelch_1 PF01344.25 PVD22235.1 - 4.6e-21 74.1 59.9 0.0075 15.8 0.0 13.3 13 0 0 13 13 13 10 Kelch motif CUB PF00431.20 PVD22235.1 - 5.6e-18 65.3 0.0 2.2e-14 53.7 0.0 3.0 2 0 0 2 2 2 2 CUB domain Laminin_EGF PF00053.24 PVD22235.1 - 3e-13 49.7 56.2 2.3e-09 37.2 17.7 20.0 15 5 3 18 18 11 4 Laminin EGF domain PSI PF01437.25 PVD22235.1 - 2.1e-08 34.6 56.9 8.3e-06 26.3 8.3 17.3 14 5 2 16 16 12 8 Plexin repeat EGF_CA PF07645.15 PVD22235.1 - 2.3e-07 30.9 25.8 1.7e-06 28.1 9.8 17.0 15 4 4 19 19 8 2 Calcium-binding EGF domain EGF_3 PF12947.7 PVD22235.1 - 3e-07 30.5 11.7 3e-07 30.5 11.7 13.2 13 2 0 13 13 7 3 EGF domain TauE PF01925.19 PVD22235.1 - 0.054 13.1 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Sulfotransfer_2 PF03567.14 PVD22236.1 - 2.9e-33 115.9 0.1 3.9e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD22236.1 - 0.00044 19.8 0.1 0.00096 18.7 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain DUF4378 PF14309.6 PVD22237.1 - 0.0095 16.3 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) HHV-1_VABD PF16852.5 PVD22238.1 - 5.1 7.2 13.5 0.53 10.3 1.0 3.5 3 0 0 3 3 3 0 Herpes viral adaptor-to-host cellular mRNA binding domain ALAD PF00490.21 PVD22240.1 - 3.7e-115 384.5 0.0 4.1e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase VWA PF00092.28 PVD22241.1 - 1.1e-18 68.1 0.5 2.1e-18 67.2 0.4 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD22241.1 - 3.2e-11 43.2 31.6 2e-05 24.7 3.8 5.2 4 1 1 5 5 5 4 Chitin binding Peritrophin-A domain VWA_2 PF13519.6 PVD22241.1 - 0.00019 22.1 0.0 0.00041 21.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain PapC_N PF13954.6 PVD22241.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 PapC N-terminal domain CBM_14 PF01607.24 PVD22242.1 - 7.3e-09 35.7 2.4 0.0021 18.2 0.7 2.2 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain VWA PF00092.28 PVD22243.1 - 7.3e-24 85.0 1.7 1.1e-23 84.4 1.7 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD22243.1 - 3.3e-13 49.6 25.8 4.9e-06 26.6 1.3 4.9 5 0 0 5 5 5 4 Chitin binding Peritrophin-A domain Copine PF07002.16 PVD22243.1 - 0.047 13.2 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Copine VWA_3 PF13768.6 PVD22243.1 - 0.11 12.5 0.2 0.24 11.3 0.2 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Pyridoxal_deC PF00282.19 PVD22245.1 - 9.4e-156 518.2 0.0 1.1e-155 518.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PVD22245.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 PVD22245.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Antimicrobial_7 PF08102.11 PVD22245.1 - 0.076 13.3 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Acyl_transf_3 PF01757.22 PVD22246.1 - 1.1e-06 27.9 22.0 5.6e-05 22.4 22.0 2.0 1 1 0 1 1 1 1 Acyltransferase family Stirrup PF09061.6 PVD22247.1 - 0.084 13.1 0.7 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 Stirrup CPG4 PF15481.6 PVD22249.1 - 0.00038 21.0 0.3 0.00038 21.0 0.3 2.4 1 1 1 2 2 2 1 Chondroitin proteoglycan 4 QVR PF17064.5 PVD22249.1 - 0.0028 17.8 1.7 0.0028 17.8 1.7 2.2 2 0 0 2 2 2 1 Sleepless protein DUF1397 PF07165.11 PVD22249.1 - 0.0053 16.2 3.0 0.055 12.9 3.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1397) VWA PF00092.28 PVD22251.1 - 7.8e-84 280.2 13.6 2.4e-43 148.4 3.3 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain Palm_thioest PF02089.15 PVD22251.1 - 4.3e-43 147.9 0.0 8.4e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase VWA_2 PF13519.6 PVD22251.1 - 2.9e-31 108.3 10.7 7.3e-16 58.8 1.0 3.8 4 0 0 4 4 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD22251.1 - 7.3e-20 71.5 6.9 2.4e-09 37.3 0.3 2.7 3 0 0 3 3 2 2 von Willebrand factor type A domain GTF2I PF02946.14 PVD22251.1 - 1.4e-17 63.5 0.1 3.5e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 GTF2I-like repeat CBM_14 PF01607.24 PVD22251.1 - 3.7e-13 49.4 24.7 0.002 18.2 0.4 5.9 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain ZapB PF06005.12 PVD22251.1 - 3.6e-05 24.1 4.3 0.00012 22.4 4.3 1.8 1 0 0 1 1 1 1 Cell division protein ZapB ATG16 PF08614.11 PVD22251.1 - 0.00025 21.4 0.1 0.00057 20.2 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Copine PF07002.16 PVD22251.1 - 0.0037 16.8 0.1 0.91 8.9 0.0 2.4 2 0 0 2 2 2 1 Copine TMF_DNA_bd PF12329.8 PVD22251.1 - 0.0058 16.6 7.0 0.31 11.1 3.5 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF3439 PF11921.8 PVD22251.1 - 0.0078 16.2 4.1 0.0078 16.2 4.1 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF3439) Lactamase_B_5 PF14597.6 PVD22251.1 - 0.01 15.3 0.7 0.57 9.6 0.1 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF1664 PF07889.12 PVD22251.1 - 0.014 15.5 3.6 0.033 14.2 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1508 PF07411.12 PVD22251.1 - 0.016 15.1 2.4 0.42 10.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) PGAP1 PF07819.13 PVD22251.1 - 0.024 14.3 0.0 0.08 12.7 0.0 1.9 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 PVD22251.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold YabA PF06156.13 PVD22251.1 - 0.035 14.8 3.8 0.11 13.2 3.8 1.8 1 0 0 1 1 1 0 Initiation control protein YabA DUF812 PF05667.11 PVD22251.1 - 0.04 12.8 1.8 0.071 12.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 PVD22251.1 - 0.053 13.5 6.5 0.13 12.3 6.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_UL42 PF02282.16 PVD22251.1 - 0.056 13.3 1.9 8.6 6.2 0.1 2.9 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) APG6_N PF17675.1 PVD22251.1 - 0.063 13.8 2.2 0.18 12.3 2.2 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 PVD22251.1 - 0.07 13.4 3.9 0.22 11.8 3.9 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 PVD22251.1 - 0.11 12.4 3.8 0.2 11.5 3.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MAD PF05557.13 PVD22251.1 - 0.11 10.8 3.3 0.17 10.2 3.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DDE_Tnp_Tn3 PF01526.17 PVD22251.1 - 0.11 11.2 0.2 8.2 5.1 0.0 2.5 2 0 0 2 2 2 0 Tn3 transposase DDE domain COG2 PF06148.11 PVD22251.1 - 0.13 12.4 1.6 1.9 8.6 3.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 PVD22251.1 - 0.17 11.2 0.3 0.4 9.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) STAT_alpha PF01017.20 PVD22251.1 - 0.22 11.4 0.9 0.39 10.6 0.9 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF2730 PF10805.8 PVD22251.1 - 0.35 11.0 3.1 0.84 9.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 PVD22251.1 - 0.43 9.4 3.2 0.78 8.6 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NRBF2 PF08961.10 PVD22251.1 - 0.52 9.9 3.4 1.1 8.8 3.4 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 PVD22251.1 - 5.1 7.3 7.1 0.4 10.8 1.6 2.0 2 0 0 2 2 1 0 bZIP transcription factor ADH_zinc_N PF00107.26 PVD22252.1 - 1.3e-23 83.4 0.1 2.1e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD22252.1 - 6.8e-14 53.1 0.0 1e-13 52.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD22252.1 - 2.3e-12 46.7 0.0 5.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 PVD22252.1 - 0.021 14.1 0.3 0.046 13.0 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.8 PVD22252.1 - 0.023 14.5 0.4 0.48 10.2 0.4 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PHP_C PF13263.6 PVD22252.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 PHP-associated ADH_N_2 PF16884.5 PVD22252.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase BNIP2 PF12496.8 PVD22253.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Amidinotransf PF02274.17 PVD22256.1 - 1.6e-10 40.6 0.0 3e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase DHHC PF01529.20 PVD22257.1 - 1.8e-35 122.0 1.9 1.8e-35 122.0 1.9 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase EcsB PF05975.12 PVD22257.1 - 0.61 8.9 6.1 0.062 12.1 1.7 1.5 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Pkinase_Tyr PF07714.17 PVD22258.1 - 3.2e-81 272.4 0.0 6.8e-79 264.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD22258.1 - 8.2e-44 149.9 0.0 4.7e-43 147.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD22258.1 - 5.4e-23 80.9 0.4 1.1e-22 79.9 0.4 1.6 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 PVD22258.1 - 7.9e-20 71.0 0.1 1.8e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 F-actin binding SH3_1 PF00018.28 PVD22258.1 - 1.7e-10 40.3 0.1 3.2e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD22258.1 - 3.2e-09 36.5 0.0 5.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD22258.1 - 2.6e-05 23.8 0.1 5.5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 PVD22258.1 - 5.3e-05 23.4 0.5 0.00013 22.2 0.5 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 PVD22258.1 - 0.027 13.4 0.0 0.056 12.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain SURF6 PF04935.12 PVD22259.1 - 1e-35 123.4 49.4 1e-35 123.4 49.4 2.0 1 1 1 2 2 2 1 Surfeit locus protein 6 PDZ_2 PF13180.6 PVD22259.1 - 0.0034 17.7 0.2 0.0034 17.7 0.2 2.1 2 1 0 2 2 2 1 PDZ domain Baculo_PEP_C PF04513.12 PVD22259.1 - 0.1 12.6 1.6 0.17 11.9 1.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_EGF PF00053.24 PVD22260.1 - 2.1e-79 261.5 236.0 1.9e-11 43.9 13.5 12.3 13 1 0 13 13 13 11 Laminin EGF domain Laminin_N PF00055.17 PVD22260.1 - 6.1e-62 209.3 0.0 6.1e-62 209.3 0.0 3.1 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 PVD22260.1 - 1.3e-25 89.9 0.0 2.7e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF2935 PF11155.8 PVD22260.1 - 0.048 14.0 3.3 18 5.7 0.0 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) Alanine_zipper PF11839.8 PVD22260.1 - 1.4 9.4 58.5 0.18 12.2 9.3 7.4 3 2 3 6 6 6 0 Alanine-zipper, major outer membrane lipoprotein Peptidase_M16 PF00675.20 PVD22261.1 - 1e-33 116.4 0.0 1.8e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PVD22261.1 - 5.3e-33 114.6 0.0 1.6e-32 113.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.8 PVD22261.1 - 0.033 14.4 0.1 0.086 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) AAA_5 PF07728.14 PVD22261.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BPL_LplA_LipB PF03099.19 PVD22262.1 - 2.1e-13 50.3 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cu2_monooxygen PF01082.20 PVD22263.1 - 9.9e-28 97.0 0.3 9.9e-28 97.0 0.3 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 PVD22263.1 - 1.5e-17 63.6 0.1 1.3e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain AIG1 PF04548.16 PVD22266.1 - 1.6e-108 360.9 9.4 4.1e-59 199.5 0.1 3.3 2 1 1 3 3 3 3 AIG1 family MMR_HSR1 PF01926.23 PVD22266.1 - 8.3e-12 45.2 1.4 1.3e-05 25.3 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD22266.1 - 2.2e-07 31.5 0.1 0.032 14.7 0.0 3.0 3 0 0 3 3 2 2 ABC transporter RsgA_GTPase PF03193.16 PVD22266.1 - 7.2e-06 26.0 0.0 0.092 12.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 PVD22266.1 - 7.3e-05 22.1 0.5 0.082 12.1 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit Dynamin_N PF00350.23 PVD22266.1 - 8.6e-05 22.7 12.4 0.68 10.0 0.8 5.5 4 2 2 6 6 4 3 Dynamin family AAA_29 PF13555.6 PVD22266.1 - 0.00074 19.2 0.0 0.5 10.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 PVD22266.1 - 0.0015 17.6 0.0 0.72 8.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 PVD22266.1 - 0.0018 17.7 0.0 1.8 7.9 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family Rad1 PF02144.16 PVD22266.1 - 0.002 17.3 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 AAA_24 PF13479.6 PVD22266.1 - 0.0034 17.1 0.2 0.4 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 PVD22266.1 - 0.0037 16.8 0.2 0.91 9.0 0.0 2.9 2 1 1 3 3 3 1 Ferrous iron transport protein B IstB_IS21 PF01695.17 PVD22266.1 - 0.0093 15.7 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 PVD22266.1 - 0.017 15.2 6.8 0.95 9.5 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 PVD22266.1 - 0.018 15.4 0.5 6.6 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD22266.1 - 0.019 15.3 0.0 9.4 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 PVD22266.1 - 0.019 13.9 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.26 PVD22266.1 - 0.026 14.2 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_15 PF13175.6 PVD22266.1 - 0.026 14.2 0.2 2.5 7.7 2.1 2.8 2 2 1 3 3 3 0 AAA ATPase domain Septin PF00735.18 PVD22266.1 - 0.03 13.6 1.5 0.31 10.3 0.0 2.7 2 1 1 3 3 3 0 Septin AAA_7 PF12775.7 PVD22266.1 - 0.036 13.6 0.1 4.8 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 PVD22266.1 - 0.046 13.7 0.3 28 4.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 PVD22266.1 - 0.055 13.3 0.1 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 PVD22266.1 - 0.1 11.8 0.0 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 PVD22266.1 - 0.11 11.9 0.1 18 4.7 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 PVD22266.1 - 0.13 12.7 0.5 20 5.7 0.1 2.8 2 0 0 2 2 2 0 RNA helicase DUF2489 PF10675.9 PVD22268.1 - 0.059 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) AhpC-TSA PF00578.21 PVD22269.1 - 1.6e-27 95.9 0.0 1.8e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PVD22269.1 - 1.7e-12 47.3 0.0 1.9e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 PVD22269.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC RasGEF PF00617.19 PVD22270.1 - 1.8e-55 187.9 0.0 3.8e-55 186.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PVD22270.1 - 2.4e-19 69.5 0.5 1.5e-17 63.8 0.1 2.9 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.23 PVD22270.1 - 5.7e-11 42.9 0.2 1.5e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain HLH PF00010.26 PVD22271.1 - 4e-07 29.9 0.1 9.9e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_1 PF00561.20 PVD22272.1 - 4e-08 33.2 0.0 1.7e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD22272.1 - 1.2e-07 32.6 0.0 5e-07 30.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD22272.1 - 4.7e-06 26.1 0.0 0.0034 16.7 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 PVD22272.1 - 0.021 13.8 0.0 0.049 12.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) SRP14 PF02290.15 PVD22272.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Mtf2_C PF14061.6 PVD22273.1 - 1.8e-07 31.2 0.0 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Use1 PF09753.9 PVD22273.1 - 0.0033 17.2 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 PHD PF00628.29 PVD22274.1 - 2.3e-11 43.4 33.7 4.1e-08 33.0 11.0 2.6 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 PVD22274.1 - 8.8e-10 38.1 0.1 1.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 PVD22274.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 PVD22274.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain 53-BP1_Tudor PF09038.10 PVD22274.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor VWA PF00092.28 PVD22275.1 - 4.9e-27 95.3 0.0 8.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD22275.1 - 4.9e-15 56.1 0.0 1.4e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Ank_2 PF12796.7 PVD22276.1 - 2.6e-68 226.6 7.2 7.4e-14 52.1 0.2 5.2 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD22276.1 - 4.5e-46 154.7 2.6 3.2e-11 43.5 0.1 7.0 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 PVD22276.1 - 2.5e-44 147.8 5.9 1.6e-06 28.2 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 PVD22276.1 - 3.3e-43 140.7 2.9 1.8e-06 27.8 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 PVD22276.1 - 5e-33 112.7 8.2 4.1e-12 46.1 0.1 5.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) DUF3885 PF13021.6 PVD22276.1 - 0.015 15.4 3.6 10 6.3 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3885) DUF4988 PF16378.5 PVD22276.1 - 0.02 14.6 0.1 1.9 8.1 0.0 3.3 2 2 2 4 4 4 0 Domain of unknown function PPR_1 PF12854.7 PVD22276.1 - 0.059 13.1 0.0 57 3.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat Fer2_4 PF13510.6 PVD22276.1 - 0.16 12.1 0.1 0.63 10.1 0.1 2.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Prefoldin PF02996.17 PVD22277.1 - 4.9e-17 62.0 0.6 8.9e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 Prefoldin subunit FRG1 PF06229.12 PVD22277.1 - 0.047 13.4 3.5 0.5 10.0 3.7 2.0 2 0 0 2 2 2 0 FRG1-like domain Glyco_hydro_8 PF01270.17 PVD22277.1 - 0.057 12.2 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 MerR-DNA-bind PF09278.11 PVD22277.1 - 0.076 13.6 0.7 0.076 13.6 0.7 3.3 3 1 0 3 3 3 0 MerR, DNA binding Stn1 PF10451.9 PVD22277.1 - 0.22 10.4 1.9 0.31 9.9 1.9 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Band_7 PF01145.25 PVD22278.1 - 7.2e-20 71.7 0.0 7.2e-20 71.7 0.0 3.2 2 1 1 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 PVD22278.1 - 2.6e-09 37.3 14.3 2.6e-09 37.3 14.3 3.8 2 2 1 3 3 3 3 Flotillin SLATT_5 PF18160.1 PVD22279.1 - 0.52 9.6 4.3 11 5.3 0.3 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TFIIB PF00382.19 PVD22283.1 - 8e-53 176.4 4.6 3.8e-27 94.1 0.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 PVD22283.1 - 2.1e-13 49.6 0.2 3.2e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 PVD22283.1 - 2.4e-07 30.6 0.1 7.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 PVD22283.1 - 3.5e-05 23.8 0.1 8.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 PVD22283.1 - 0.0047 17.0 0.1 2 8.5 0.0 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 PVD22283.1 - 0.0097 15.4 0.1 0.047 13.2 0.1 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 zf-C3HC4_3 PF13920.6 PVD22284.1 - 2.8e-12 46.3 14.3 4.3e-12 45.7 14.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22284.1 - 1.6e-06 27.8 14.0 3e-06 27.0 14.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2457 PF10446.9 PVD22284.1 - 0.051 12.7 11.3 0.065 12.4 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-RING_14 PF17978.1 PVD22284.1 - 0.29 11.6 7.6 0.53 10.7 7.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YqfQ PF14181.6 PVD22284.1 - 6.5 6.9 6.2 19 5.4 6.2 1.7 1 1 0 1 1 1 0 YqfQ-like protein zf-C3HC4_3 PF13920.6 PVD22285.1 - 1.1e-12 47.5 7.7 1.8e-12 46.9 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22285.1 - 6.1e-07 29.2 7.3 1.1e-06 28.4 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22285.1 - 2.4e-05 24.6 9.8 3.7e-05 24.0 9.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD22285.1 - 0.00032 20.6 9.0 0.00054 19.9 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD22285.1 - 0.0034 17.2 8.4 0.0055 16.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 PVD22285.1 - 0.0048 16.5 2.3 0.0075 15.9 2.3 1.3 1 0 0 1 1 1 1 P-11 zinc finger Pellino PF04710.14 PVD22285.1 - 0.055 12.1 0.8 0.073 11.7 0.8 1.1 1 0 0 1 1 1 0 Pellino zf-RING_UBOX PF13445.6 PVD22285.1 - 0.21 11.7 6.3 0.17 11.9 2.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DZR PF12773.7 PVD22285.1 - 1.2 9.2 6.5 0.3 11.1 2.0 1.7 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.15 PVD22285.1 - 1.6 8.4 13.5 0.64 9.6 6.0 2.4 2 0 0 2 2 2 0 RecR protein zf-RING_4 PF14570.6 PVD22285.1 - 1.7 8.5 10.9 16 5.4 10.8 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain HCR PF07111.12 PVD22286.1 - 7.2e-41 140.1 96.4 1.3e-40 139.2 96.3 1.5 1 1 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) ADK PF00406.22 PVD22287.1 - 6.1e-51 172.5 0.0 3.1e-37 128.0 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 PVD22287.1 - 3.6e-21 76.0 0.1 2.8e-14 53.7 0.0 2.8 2 1 1 3 3 3 2 AAA domain Hydin_ADK PF17213.3 PVD22287.1 - 2.4e-09 37.7 0.5 0.13 12.5 0.1 4.0 3 1 1 4 4 4 3 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 PVD22287.1 - 2.6e-06 28.0 0.0 0.011 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PVD22287.1 - 0.0014 18.8 0.1 1.8 8.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 PVD22287.1 - 0.023 14.4 0.9 5.8 6.5 0.1 3.8 4 1 0 4 4 4 0 Thymidylate kinase AAA PF00004.29 PVD22287.1 - 0.027 14.9 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 PVD22287.1 - 0.43 10.7 1.6 52 3.9 0.2 3.8 3 1 0 3 3 3 0 Shikimate kinase Mito_carr PF00153.27 PVD22288.1 - 4.9e-20 71.2 0.1 3.6e-09 36.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_4 PF15227.6 PVD22289.1 - 0.00032 20.8 11.9 0.0032 17.6 12.1 2.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD22289.1 - 0.015 15.3 11.4 0.078 13.0 11.4 2.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD22289.1 - 0.029 14.2 12.2 0.15 11.9 12.2 2.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22289.1 - 0.15 12.0 11.0 0.74 9.8 11.0 2.4 1 0 0 1 1 1 0 zinc-RING finger domain RIG-I_C-RD PF11648.8 PVD22290.1 - 2.2e-25 89.2 3.0 5.5e-24 84.6 2.6 2.7 2 0 0 2 2 2 1 C-terminal domain of RIG-I ResIII PF04851.15 PVD22290.1 - 8.8e-21 74.6 0.0 3.3e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD22290.1 - 1e-18 67.7 0.0 2.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD22290.1 - 2.7e-17 63.1 0.0 2.5e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RIG-I_C PF18119.1 PVD22290.1 - 1.5e-12 47.7 0.1 6.3e-12 45.7 0.1 2.1 1 1 0 1 1 1 1 RIG-I receptor C-terminal domain SWI2_SNF2 PF18766.1 PVD22290.1 - 4.3e-08 33.1 0.0 5.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase TniB PF05621.11 PVD22290.1 - 0.00015 21.2 0.0 0.0022 17.4 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein PhoH PF02562.16 PVD22290.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Yippee-Mis18 PF03226.14 PVD22290.1 - 0.24 11.6 2.1 0.65 10.2 2.1 1.7 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AIG1 PF04548.16 PVD22291.1 - 7.2e-32 110.4 2.4 1.3e-23 83.5 0.1 2.1 1 1 1 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 PVD22291.1 - 4.2e-06 26.8 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 PVD22291.1 - 3.9e-05 23.1 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 PVD22291.1 - 5.6e-05 23.3 1.0 0.0053 16.8 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PVD22291.1 - 6.2e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sigma54_activat PF00158.26 PVD22291.1 - 0.0057 16.4 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain RNase_II_C_S1 PF18614.1 PVD22291.1 - 0.0064 16.4 1.2 0.013 15.4 1.2 1.5 1 0 0 1 1 1 1 RNase II-type exonuclease C-terminal S1 domain AAA_22 PF13401.6 PVD22291.1 - 0.018 15.3 0.1 0.19 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD22291.1 - 0.032 14.7 0.1 0.79 10.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 PVD22291.1 - 0.038 14.4 0.6 0.44 10.9 0.5 2.5 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 PVD22291.1 - 0.11 12.2 0.0 2.5 7.8 0.0 2.4 1 1 0 1 1 1 0 IstB-like ATP binding protein Methyltransf_7 PF03492.15 PVD22293.1 - 4.6e-05 22.8 0.0 6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase DUF429 PF04250.13 PVD22293.1 - 0.041 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Transglut_core PF01841.19 PVD22294.1 - 2.3e-24 86.0 11.1 0.0002 21.8 0.1 7.4 7 0 0 7 7 7 5 Transglutaminase-like superfamily Imm64 PF15600.6 PVD22294.1 - 2.8 7.6 8.0 34 4.0 0.3 4.3 4 0 0 4 4 4 0 Immunity protein 64 Cyclin_C PF02984.19 PVD22295.1 - 0.015 15.4 8.4 12 6.0 0.1 4.5 4 0 0 4 4 4 0 Cyclin, C-terminal domain DUF4115 PF13464.6 PVD22295.1 - 0.072 13.3 0.1 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) DUF4854 PF16146.5 PVD22295.1 - 0.3 11.5 6.3 12 6.3 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4854) CDC37_C PF08564.10 PVD22295.1 - 0.4 10.8 24.7 0.8 9.9 0.2 7.5 7 1 1 8 8 8 0 Cdc37 C terminal domain FANCI_S1-cap PF14674.6 PVD22295.1 - 7.8 6.7 6.1 20 5.4 0.0 4.6 6 0 0 6 6 6 0 FANCI solenoid 1 cap Transglut_core PF01841.19 PVD22296.1 - 3.4e-16 59.7 1.0 0.0013 19.2 0.0 3.8 3 0 0 3 3 3 3 Transglutaminase-like superfamily DNA_ligase_IV PF11411.8 PVD22296.1 - 0.0062 16.6 1.8 39 4.5 0.1 4.3 3 0 0 3 3 3 0 DNA ligase IV DUF4854 PF16146.5 PVD22296.1 - 0.021 15.1 0.3 8.1 6.8 0.0 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) TetR_C_11 PF16859.5 PVD22296.1 - 0.024 15.0 0.1 18 5.7 0.0 3.8 4 0 0 4 4 3 0 Tetracyclin repressor-like, C-terminal domain Bac_DnaA_C PF08299.11 PVD22296.1 - 0.23 11.5 2.1 26 4.9 0.0 3.9 4 0 0 4 4 4 0 Bacterial dnaA protein helix-turn-helix MTHFR_C PF12225.8 PVD22296.1 - 0.45 10.2 3.3 3.9 7.2 0.2 3.9 3 0 0 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal SwrA PF17423.2 PVD22296.1 - 0.65 10.0 10.2 3.2 7.7 0.1 4.0 4 0 0 4 4 4 0 Swarming motility protein Myosin_N PF02736.19 PVD22296.1 - 3.5 7.5 5.1 1.1e+02 2.8 0.1 3.8 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain EspA PF03433.13 PVD22296.1 - 5.3 6.8 16.4 1 9.2 0.6 3.6 5 0 0 5 5 5 0 EspA-like secreted protein Toxin_36 PF10550.9 PVD22296.1 - 6 8.5 8.0 1.7e+02 4.0 0.1 4.7 3 0 0 3 3 3 0 Conantokin-G mollusc-toxin Cyclin_C PF02984.19 PVD22296.1 - 9.9 6.3 17.8 13 5.9 0.3 5.3 5 0 0 5 5 5 0 Cyclin, C-terminal domain Transglut_core PF01841.19 PVD22297.1 - 5e-05 23.7 0.0 0.013 16.0 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase-like superfamily SwrA PF17423.2 PVD22297.1 - 0.023 14.6 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 Swarming motility protein Ribosomal_L5 PF00281.19 PVD22297.1 - 0.029 14.7 0.1 0.082 13.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L5 DUF3242 PF11586.8 PVD22297.1 - 0.031 14.0 0.1 0.09 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Transglut_core PF01841.19 PVD22299.1 - 3.4e-10 40.4 0.2 0.00067 20.1 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase-like superfamily PapG_N PF03627.13 PVD22299.1 - 0.04 13.6 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 PapG carbohydrate binding domain pEK499_p136 PF18736.1 PVD22299.1 - 0.058 13.0 1.0 0.11 12.1 1.0 1.5 1 0 0 1 1 1 0 HEPN pEK499 p136 Cytochrom_B562 PF07361.11 PVD22299.1 - 0.28 11.9 1.5 1.3 9.8 1.4 2.2 1 1 0 1 1 1 0 Cytochrome b562 TINF2_N PF14973.6 PVD22299.1 - 3 8.2 10.5 0.84 10.0 3.2 3.1 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Synaptobrevin PF00957.21 PVD22300.1 - 3.3e-32 110.1 0.4 4.1e-32 109.8 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin PspB PF06667.12 PVD22300.1 - 0.0017 18.4 2.1 0.0025 17.8 0.7 1.9 2 0 0 2 2 2 1 Phage shock protein B Ferlin_C PF16165.5 PVD22300.1 - 0.02 14.9 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus 7TM_GPCR_Srh PF10318.9 PVD22300.1 - 0.023 13.7 0.5 0.028 13.4 0.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Orf78 PF06024.12 PVD22300.1 - 0.03 14.6 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) ASFV_J13L PF05568.11 PVD22300.1 - 0.12 12.2 1.9 0.16 11.7 1.9 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein EMP24_GP25L PF01105.24 PVD22300.1 - 0.13 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OppC_N PF12911.7 PVD22300.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF515 PF04415.12 PVD22300.1 - 1.2 7.5 3.2 1.2 7.4 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF515) Arginosuc_synth PF00764.19 PVD22301.1 - 2.2e-162 540.8 0.0 2.5e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 PVD22301.1 - 0.00014 21.5 0.1 0.00034 20.2 0.1 1.4 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 PVD22301.1 - 0.025 13.4 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase C1q PF00386.21 PVD22302.1 - 8.7e-18 64.8 0.2 1.5e-17 64.0 0.1 1.5 1 1 0 1 1 1 1 C1q domain PA14 PF07691.12 PVD22302.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FlxA PF14282.6 PVD22302.1 - 0.0047 16.9 1.6 0.0067 16.4 1.6 1.2 1 0 0 1 1 1 1 FlxA-like protein Spc24 PF08286.11 PVD22302.1 - 0.0084 16.3 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 E2F_CC-MB PF16421.5 PVD22302.1 - 0.054 13.9 0.5 0.091 13.1 0.5 1.3 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF4988 PF16378.5 PVD22302.1 - 0.097 12.3 0.1 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Surfac_D-trimer PF09006.11 PVD22302.1 - 0.23 11.4 1.0 0.48 10.4 1.0 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Methyltransf_7 PF03492.15 PVD22303.1 - 4.6e-14 52.4 0.2 5.9e-14 52.0 0.2 1.0 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Exo_endo_phos_2 PF14529.6 PVD22304.1 - 2.6e-09 36.9 0.1 4.8e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD22304.1 - 2.4e-07 30.5 0.0 4.3e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Synaptobrevin PF00957.21 PVD22305.1 - 3.3e-32 110.1 0.4 4.1e-32 109.8 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin PspB PF06667.12 PVD22305.1 - 0.0017 18.4 2.1 0.0025 17.8 0.7 1.9 2 0 0 2 2 2 1 Phage shock protein B Ferlin_C PF16165.5 PVD22305.1 - 0.02 14.9 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus 7TM_GPCR_Srh PF10318.9 PVD22305.1 - 0.023 13.7 0.5 0.028 13.4 0.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Orf78 PF06024.12 PVD22305.1 - 0.03 14.6 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) ASFV_J13L PF05568.11 PVD22305.1 - 0.12 12.2 1.9 0.16 11.7 1.9 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein EMP24_GP25L PF01105.24 PVD22305.1 - 0.13 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OppC_N PF12911.7 PVD22305.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF515 PF04415.12 PVD22305.1 - 1.2 7.5 3.2 1.2 7.4 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF515) Arginosuc_synth PF00764.19 PVD22306.1 - 2.4e-112 376.1 0.0 2.1e-73 247.9 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase QueC PF06508.13 PVD22306.1 - 6.7e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 PVD22306.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase C1q PF00386.21 PVD22307.1 - 3.9e-18 65.9 0.2 7.1e-18 65.0 0.1 1.5 1 1 0 1 1 1 1 C1q domain FlxA PF14282.6 PVD22307.1 - 0.0047 16.9 1.6 0.0067 16.4 1.6 1.2 1 0 0 1 1 1 1 FlxA-like protein PA14 PF07691.12 PVD22307.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Spc24 PF08286.11 PVD22307.1 - 0.008 16.4 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 GLEYA PF10528.9 PVD22307.1 - 0.043 14.2 0.2 0.088 13.2 0.0 1.7 2 0 0 2 2 2 0 GLEYA domain E2F_CC-MB PF16421.5 PVD22307.1 - 0.054 13.9 0.5 0.091 13.1 0.5 1.3 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF4988 PF16378.5 PVD22307.1 - 0.11 12.2 0.1 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Ctr PF04145.15 PVD22308.1 - 8.4e-34 117.3 6.8 1.3e-33 116.7 6.8 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 PVD22309.1 - 7.7e-12 46.1 15.8 5.7e-10 40.0 9.6 2.6 2 1 1 3 3 3 2 Ctr copper transporter family TFIIA PF03153.13 PVD22310.1 - 0.74 9.7 21.9 1 9.3 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IRS PF02174.17 PVD22311.1 - 7.4e-15 54.7 0.0 3e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Ctr PF04145.15 PVD22312.1 - 2.7e-11 44.3 7.3 2.7e-11 44.3 7.3 1.5 2 0 0 2 2 2 1 Ctr copper transporter family VirB3 PF05101.13 PVD22312.1 - 0.023 14.9 0.5 0.028 14.6 0.5 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein TelA PF05816.11 PVD22312.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) IQ_SEC7_PH PF16453.5 PVD22314.1 - 0.015 15.3 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 PH domain ssDNA-exonuc_C PF10141.9 PVD22314.1 - 0.35 10.5 4.8 0.56 9.8 0.0 2.9 3 0 0 3 3 3 0 Single-strand DNA-specific exonuclease, C terminal domain NPDC1 PF06809.11 PVD22315.1 - 1.2e-35 123.2 0.1 1.4e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) CD20 PF04103.15 PVD22315.1 - 0.022 14.9 0.4 0.045 13.8 0.2 1.6 1 1 1 2 2 2 0 CD20-like family EBV-NA3 PF05009.12 PVD22315.1 - 0.051 13.1 0.2 0.078 12.5 0.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Snapin_Pallidin PF14712.6 PVD22316.1 - 3.6e-28 97.8 2.3 4.7e-28 97.4 2.3 1.1 1 0 0 1 1 1 1 Snapin/Pallidin XhlA PF10779.9 PVD22316.1 - 1.5e-05 25.1 5.0 0.00037 20.6 0.9 2.3 2 0 0 2 2 2 1 Haemolysin XhlA Eisosome1 PF12757.7 PVD22316.1 - 0.00021 21.6 2.1 0.0069 16.6 0.3 2.3 2 0 0 2 2 2 1 Eisosome protein 1 Laminin_II PF06009.12 PVD22316.1 - 0.00066 19.7 3.5 0.0015 18.5 3.5 1.6 1 1 0 1 1 1 1 Laminin Domain II PTRF_SDPR PF15237.6 PVD22316.1 - 0.0031 17.2 2.7 0.0041 16.8 2.7 1.1 1 0 0 1 1 1 1 PTRF/SDPR family Flagellar_rod PF05149.12 PVD22316.1 - 0.0065 16.0 2.0 0.0075 15.8 2.0 1.1 1 0 0 1 1 1 1 Paraflagellar rod protein CENP-H PF05837.12 PVD22316.1 - 0.007 16.8 4.1 0.06 13.7 4.1 2.0 1 1 0 1 1 1 1 Centromere protein H (CENP-H) TRPM_tetra PF16519.5 PVD22316.1 - 0.0087 16.1 4.2 0.43 10.7 0.2 2.2 2 0 0 2 2 2 2 Tetramerisation domain of TRPM DUF4164 PF13747.6 PVD22316.1 - 0.015 15.6 2.5 0.024 14.9 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 PVD22316.1 - 0.026 14.7 2.2 0.033 14.4 2.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.9 PVD22316.1 - 0.031 13.1 1.6 0.038 12.9 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.6 PVD22316.1 - 0.055 13.5 3.5 0.28 11.2 3.5 1.9 1 1 0 1 1 1 0 FlxA-like protein FlaC_arch PF05377.11 PVD22316.1 - 0.067 13.6 5.2 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 PVD22316.1 - 0.07 11.7 2.0 0.081 11.5 2.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF489 PF04356.12 PVD22316.1 - 0.07 13.1 0.3 0.077 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) NPV_P10 PF05531.12 PVD22316.1 - 0.076 13.5 5.3 3 8.4 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PVD22316.1 - 0.083 12.9 2.6 0.15 12.1 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 PVD22316.1 - 0.12 10.9 3.4 0.12 10.9 3.4 1.0 1 0 0 1 1 1 0 Macoilin family BLOC1_2 PF10046.9 PVD22316.1 - 0.13 12.6 2.8 0.2 11.9 0.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_MT_bd PF06657.13 PVD22316.1 - 0.13 12.7 3.4 0.82 10.2 0.0 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4665 PF15679.5 PVD22316.1 - 0.15 12.7 4.1 0.26 11.9 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Nup54 PF13874.6 PVD22316.1 - 0.17 12.0 4.6 4.7 7.3 1.5 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF16 PF01519.16 PVD22316.1 - 0.22 12.0 2.9 0.32 11.5 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1284 PF06935.11 PVD22316.1 - 0.28 11.6 1.1 0.4 11.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) GIT_CC PF16559.5 PVD22316.1 - 0.45 10.4 4.5 2.3 8.1 2.3 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Latarcin PF10279.9 PVD22316.1 - 0.69 10.4 4.1 4.3 7.8 4.1 2.1 1 1 0 1 1 1 0 Latarcin precursor Prefoldin PF02996.17 PVD22316.1 - 4.4 7.3 8.0 2.3 8.1 0.3 2.6 2 1 0 3 3 3 0 Prefoldin subunit BAG6 PF12057.8 PVD22317.1 - 1.1e-20 73.5 1.6 1.1e-20 73.5 1.6 2.6 2 0 0 2 2 2 1 BCL2-associated athanogene 6 ubiquitin PF00240.23 PVD22317.1 - 2e-19 69.1 0.2 5.3e-19 67.7 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD22317.1 - 2.2e-08 33.8 0.4 5.1e-08 32.6 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 PVD22317.1 - 0.00027 21.0 0.0 0.00077 19.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PVD22317.1 - 0.00074 19.9 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Sarcoglycan_1 PF04790.13 PVD22317.1 - 0.00076 18.9 0.6 0.0019 17.6 0.6 1.6 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2407 PF10302.9 PVD22317.1 - 0.048 14.2 0.0 0.35 11.5 0.0 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 PVD22317.1 - 0.057 13.4 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain FERM_N PF09379.10 PVD22317.1 - 0.072 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain UN_NPL4 PF11543.8 PVD22317.1 - 0.13 12.8 0.0 0.55 10.7 0.0 2.1 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Proteasome PF00227.26 PVD22318.1 - 4.6e-34 117.6 0.0 6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.15 PVD22318.1 - 0.033 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family LSM PF01423.22 PVD22319.1 - 3.7e-17 61.8 0.0 4.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PVD22319.1 - 0.0036 17.4 0.1 0.0048 17.0 0.1 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain WD40 PF00400.32 PVD22320.1 - 6e-26 90.2 6.5 5e-07 30.3 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD22320.1 - 1.5e-09 38.1 0.4 4.2e-05 23.8 0.1 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD22320.1 - 1.5e-07 30.4 1.6 0.0031 16.2 0.5 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 PVD22320.1 - 3.5e-06 27.0 0.4 0.0032 17.4 0.0 2.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PVD22320.1 - 0.097 12.0 0.0 7.4 5.8 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain PRP38 PF03371.15 PVD22321.1 - 3.1e-56 190.0 0.0 4.3e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 PRP38 family SRP-alpha_N PF04086.13 PVD22321.1 - 9.7 6.0 33.8 12 5.7 33.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RINGv PF12906.7 PVD22322.1 - 3.8e-13 49.3 7.2 3.8e-13 49.3 7.2 2.2 2 0 0 2 2 2 1 RING-variant domain EGF_Tenascin PF18720.1 PVD22322.1 - 0.011 15.7 9.3 0.03 14.4 9.3 1.8 1 0 0 1 1 1 0 Tenascin EGF domain SK_channel PF03530.14 PVD22322.1 - 0.045 13.7 0.7 0.045 13.7 0.7 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Toxin_5 PF05294.13 PVD22322.1 - 6.3 7.3 12.6 4.1 7.9 7.5 2.8 2 0 0 2 2 2 0 Scorpion short toxin Pkinase PF00069.25 PVD22323.1 - 4.5e-63 213.1 0.0 3e-62 210.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain HR1 PF02185.16 PVD22323.1 - 2.8e-42 142.7 43.8 3.4e-17 62.3 6.8 4.7 4 1 1 5 5 5 3 Hr1 repeat Pkinase_Tyr PF07714.17 PVD22323.1 - 3.4e-39 134.7 0.0 7.2e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PVD22323.1 - 3.8e-12 46.7 1.4 1.4e-11 44.9 1.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 PVD22323.1 - 6.6e-08 32.2 0.2 2.1e-06 27.3 0.0 3.1 4 0 0 4 4 4 1 Kinase-like Uds1 PF15456.6 PVD22323.1 - 0.002 18.3 32.3 0.0053 16.9 2.9 4.1 3 1 1 4 4 4 2 Up-regulated During Septation PIP49_C PF12260.8 PVD22324.1 - 1.7e-35 122.4 0.4 2.6e-35 121.8 0.4 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 PVD22324.1 - 2.9e-07 30.5 2.6 2.9e-07 30.5 2.6 2.9 2 1 0 2 2 2 1 N-term cysteine-rich ER, FAM69 RNase_T PF00929.24 PVD22326.1 - 2.7e-23 83.3 0.1 2.4e-10 41.2 0.0 3.1 2 2 0 2 2 2 2 Exonuclease DUF5051 PF16473.5 PVD22326.1 - 2.2e-13 50.5 0.0 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease, RNase T-like Borrelia_orfD PF02999.14 PVD22326.1 - 0.00069 19.9 0.1 0.98 9.8 0.0 2.6 2 0 0 2 2 2 2 Borrelia orf-D family DUF2653 PF10850.8 PVD22326.1 - 0.0013 18.9 0.0 6.1 7.1 0.0 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2653) Csm1_B PF18211.1 PVD22326.1 - 0.023 14.5 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Csm1 subunit domain B ExbD PF02472.16 PVD22326.1 - 0.078 13.2 0.0 9.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DUF1896 PF08989.10 PVD22326.1 - 0.12 12.4 0.5 20 5.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) Plant_NMP1 PF06694.11 PVD22326.1 - 0.16 11.0 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) RNase_T PF00929.24 PVD22327.1 - 5e-11 43.4 0.0 1.2e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 PVD22327.1 - 0.0044 17.0 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Sulfotransfer_1 PF00685.27 PVD22329.1 - 0.00013 21.6 0.1 0.00029 20.4 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD22329.1 - 0.0011 19.4 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Pox_mRNA-cap PF03341.13 PVD22329.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit CUB PF00431.20 PVD22330.1 - 9.4e-46 154.7 0.0 2.9e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 CUB domain PAN_1 PF00024.26 PVD22330.1 - 2.8e-35 120.1 10.7 4.2e-09 36.2 0.0 4.4 4 0 0 4 4 4 4 PAN domain CUB_2 PF02408.20 PVD22330.1 - 0.007 16.1 6.4 1.2 8.9 0.2 3.8 3 1 0 3 3 3 2 CUB-like domain Carb_bind PF10645.9 PVD22330.1 - 0.012 15.8 9.5 11 6.4 0.1 5.2 5 0 0 5 5 5 0 Carbohydrate binding Branch PF02485.21 PVD22331.1 - 2.8e-39 135.1 0.0 4.6e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ig_C17orf99 PF17736.1 PVD22331.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 C17orf99 Ig domain LRAT PF04970.13 PVD22332.1 - 3.1e-21 76.0 0.0 4.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase FPP PF05911.11 PVD22332.1 - 0.029 12.6 0.0 0.03 12.5 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil FliMN_C PF01052.20 PVD22332.1 - 0.089 12.8 0.1 0.21 11.6 0.1 1.8 1 1 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term RasGEF PF00617.19 PVD22333.1 - 4.1e-52 176.9 0.4 1.6e-51 175.0 0.4 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PVD22333.1 - 1.3e-10 41.4 0.0 4.4e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Sec1 PF00995.23 PVD22337.1 - 1.2e-124 417.7 0.4 1.3e-124 417.5 0.4 1.0 1 0 0 1 1 1 1 Sec1 family YscO PF07321.12 PVD22337.1 - 0.7 9.8 8.9 0.92 9.5 7.3 2.0 3 0 0 3 3 3 0 Type III secretion protein YscO Ribosomal_L7Ae PF01248.26 PVD22338.1 - 9.9e-23 79.7 0.1 1.7e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med22 PF06179.12 PVD22339.1 - 1.7e-30 105.3 2.9 2.2e-30 105.0 2.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPRTase PF14681.6 PVD22339.1 - 0.036 13.5 0.1 0.044 13.2 0.1 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TUDOR PF00567.24 PVD22339.1 - 0.085 12.9 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 Tudor domain PsaD PF02531.16 PVD22339.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 PsaD Pkinase PF00069.25 PVD22340.1 - 2.2e-45 155.1 1.3 2e-34 119.2 0.1 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22340.1 - 1.4e-26 93.3 3.5 2.2e-21 76.3 0.1 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD22340.1 - 5.5e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD22340.1 - 0.0018 17.7 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PVD22340.1 - 0.021 14.4 0.8 0.17 11.5 0.0 2.5 3 0 0 3 3 3 0 RIO1 family Haspin_kinase PF12330.8 PVD22340.1 - 0.038 12.9 0.0 0.098 11.6 0.0 1.8 1 0 0 1 1 1 0 Haspin like kinase domain HEAT PF02985.22 PVD22340.1 - 0.047 14.0 0.5 11 6.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Kdo PF06293.14 PVD22340.1 - 0.075 12.4 0.1 0.29 10.4 0.0 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PVD22340.1 - 0.098 12.3 0.1 14 5.3 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PVD22340.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SSPI PF14098.6 PVD22340.1 - 0.12 12.5 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 Small, acid-soluble spore protein I Arm PF00514.23 PVD22340.1 - 0.2 11.7 2.4 29 4.9 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 PVD22340.1 - 0.24 11.4 4.2 7.1 6.7 0.1 3.7 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain PLA2_B PF01735.18 PVD22341.1 - 1e-81 274.9 0.0 5.3e-81 272.5 0.0 1.9 2 0 0 2 2 2 1 Lysophospholipase catalytic domain C2 PF00168.30 PVD22341.1 - 9.8e-14 51.5 0.1 2.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain Patatin PF01734.22 PVD22341.1 - 0.0024 18.1 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase HD-ZIP_N PF04618.12 PVD22341.1 - 0.021 15.3 0.1 0.082 13.4 0.1 2.0 1 1 0 1 1 1 0 HD-ZIP protein N terminus Treacle PF03546.14 PVD22341.1 - 0.042 12.7 1.2 0.059 12.2 1.2 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Ank_2 PF12796.7 PVD22342.1 - 1.7e-28 99.0 0.0 7.1e-13 49.0 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22342.1 - 9.1e-24 83.2 2.6 1.3e-08 34.9 0.1 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD22342.1 - 1.7e-23 82.6 1.7 1.4e-09 38.2 0.0 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD22342.1 - 1.9e-19 69.2 0.6 0.00025 21.3 0.1 6.4 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PVD22342.1 - 8.6e-19 65.7 0.2 0.00094 19.5 0.1 6.3 5 0 0 5 5 5 5 Ankyrin repeat Pre-SET PF05033.16 PVD22342.1 - 3.3e-14 53.4 9.7 3.3e-14 53.4 9.7 3.9 3 0 0 3 3 3 1 Pre-SET motif SET PF00856.28 PVD22342.1 - 9.1e-13 48.9 3.1 2e-12 47.9 0.8 2.7 3 0 0 3 3 3 1 SET domain Ion_trans PF00520.31 PVD22347.1 - 5.1e-247 815.1 83.1 5.7e-65 218.9 21.3 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 PVD22347.1 - 1.8e-30 104.5 0.0 5.2e-30 103.0 0.1 1.8 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 PVD22347.1 - 4.3e-29 100.6 0.1 9e-29 99.5 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 PVD22347.1 - 4.6e-10 38.8 78.7 3.4e-07 29.3 4.1 9.8 7 3 2 10 10 10 7 Polycystin cation channel DSL PF01414.19 PVD22347.1 - 0.021 15.1 0.4 0.048 13.9 0.4 1.5 1 0 0 1 1 1 0 Delta serrate ligand EGF_CA PF07645.15 PVD22347.1 - 0.23 11.7 1.8 0.38 11.0 0.6 1.9 2 0 0 2 2 2 0 Calcium-binding EGF domain Pox_I5 PF04713.12 PVD22347.1 - 0.47 10.5 7.3 7.2 6.7 0.3 4.9 4 0 0 4 4 4 0 Poxvirus protein I5 Urm1 PF09138.11 PVD22348.1 - 2.2e-26 92.0 0.1 2.6e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Glyco_transf_10 PF00852.19 PVD22349.1 - 1.1e-41 142.5 1.4 1.5e-41 142.1 1.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term CRF1 PF10380.9 PVD22349.1 - 0.17 12.2 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor CRF1 Glyco_transf_10 PF00852.19 PVD22350.1 - 1.7e-42 145.1 1.1 2.5e-42 144.6 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD22350.1 - 6.2e-13 49.2 0.0 1.5e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF1647 PF07801.11 PVD22352.1 - 7.2e-22 77.7 0.5 1.5e-08 34.5 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF1647) oligo_HPY PF08352.12 PVD22352.1 - 0.0089 16.5 0.1 80 3.9 0.0 3.6 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region PseudoU_synth_2 PF00849.22 PVD22352.1 - 0.0095 16.0 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 2 RNA pseudouridylate synthase OmpW PF03922.14 PVD22352.1 - 0.012 15.5 0.0 5.1 6.9 0.0 3.4 3 0 0 3 3 3 0 OmpW family ICAT PF06384.11 PVD22352.1 - 0.014 15.7 0.0 17 5.8 0.0 3.0 3 0 0 3 3 3 0 Beta-catenin-interacting protein ICAT DUF1647 PF07801.11 PVD22355.1 - 2.8e-11 43.4 0.0 1.8e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1647) Glyco_transf_10 PF00852.19 PVD22356.1 - 3.7e-43 147.3 1.0 5.5e-43 146.7 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD22356.1 - 1e-13 51.7 0.1 2.2e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF1647 PF07801.11 PVD22357.1 - 7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Glyco_transf_10 PF00852.19 PVD22358.1 - 7.5e-41 139.8 0.6 1.1e-40 139.2 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD22358.1 - 7.2e-14 52.2 0.1 1.6e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD22359.1 - 4e-40 137.4 1.5 6e-40 136.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD22359.1 - 9e-12 45.4 0.1 1.8e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal ANAPC5 PF12862.7 PVD22360.1 - 3.5e-26 91.1 13.4 3.8e-26 91.0 3.5 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 PVD22360.1 - 1.1e-05 25.7 7.1 0.00095 19.4 1.4 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD22360.1 - 0.0022 18.5 5.6 29 5.6 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22360.1 - 0.0076 16.7 13.8 0.49 10.9 0.1 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22360.1 - 0.26 11.6 1.9 1.1e+02 3.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD22360.1 - 0.42 10.9 13.9 2.5 8.4 1.3 4.8 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD22360.1 - 0.59 11.1 0.1 0.59 11.1 0.1 6.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22360.1 - 4.6 7.5 11.4 43 4.4 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat FMO-like PF00743.19 PVD22361.1 - 6.8e-209 694.7 0.0 8.4e-209 694.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD22361.1 - 1.3e-15 57.4 0.0 7.4e-11 41.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD22361.1 - 3.8e-10 39.5 0.0 2.3e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD22361.1 - 7.8e-09 35.1 0.1 1.3e-05 24.5 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PVD22361.1 - 6.2e-05 23.2 0.1 0.00023 21.3 0.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PVD22361.1 - 0.0039 17.7 0.3 6.3 7.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD22361.1 - 0.01 15.5 0.1 3.7 7.0 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PVD22361.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 PVD22361.1 - 0.11 11.7 0.1 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 PVD22361.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 PVD22361.1 - 0.57 10.2 3.0 6.1 6.8 0.1 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding FMO-like PF00743.19 PVD22362.1 - 6.2e-197 655.2 0.0 7e-197 655.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD22362.1 - 7.7e-19 68.1 0.0 6.2e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD22362.1 - 1.1e-13 51.1 0.0 6.9e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD22362.1 - 1.6e-11 44.0 0.5 6.5e-09 35.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 PVD22362.1 - 6.5e-07 29.8 0.6 0.0077 16.8 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD22362.1 - 3.2e-05 24.1 1.0 0.00014 22.0 0.1 2.6 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PVD22362.1 - 0.0018 18.3 0.3 8.5 6.3 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 PVD22362.1 - 0.0025 17.5 0.8 1.3 8.6 0.0 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase IlvN PF07991.12 PVD22362.1 - 0.029 14.0 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 PVD22362.1 - 0.049 12.7 0.2 2.4 7.1 0.0 2.7 2 1 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 PVD22362.1 - 0.11 11.8 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 PVD22362.1 - 0.12 11.7 0.2 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PVD22362.1 - 0.13 11.6 0.0 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PVD22362.1 - 0.13 10.9 0.4 3 6.5 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 PVD22362.1 - 0.19 11.1 0.1 0.89 8.9 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 PVD22363.1 - 1.1e-189 631.3 0.0 1.3e-189 631.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD22363.1 - 6.6e-19 68.3 0.0 1.1e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD22363.1 - 2.7e-13 49.8 0.0 1.1e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD22363.1 - 4.7e-11 42.4 1.0 5.7e-09 35.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 PVD22363.1 - 5.4e-07 30.1 0.6 0.0075 16.8 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD22363.1 - 2.9e-05 24.2 0.7 0.00029 21.0 0.0 2.9 3 1 1 4 4 4 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PVD22363.1 - 0.0048 16.9 0.4 10 6.1 0.0 3.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 PVD22363.1 - 0.0068 16.0 2.3 1.2 8.6 0.0 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase Peptidase_M17_N PF02789.17 PVD22363.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain FAD_oxidored PF12831.7 PVD22363.1 - 0.088 12.1 0.3 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 PVD22363.1 - 0.093 12.3 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 PVD22363.1 - 0.14 11.4 0.1 0.94 8.7 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PVD22363.1 - 0.17 10.6 0.2 2.8 6.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FMO-like PF00743.19 PVD22364.1 - 3.4e-193 642.9 0.0 3.8e-193 642.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD22364.1 - 1.7e-18 66.9 0.0 9.3e-14 51.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD22364.1 - 2.4e-13 50.0 0.0 1.1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD22364.1 - 2.1e-11 43.6 0.5 5.8e-09 35.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 PVD22364.1 - 7.7e-06 26.4 0.8 0.0081 16.7 0.1 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD22364.1 - 1.5e-05 25.1 0.6 0.00019 21.6 0.1 3.0 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PVD22364.1 - 0.0024 17.9 0.3 10 6.1 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding Peptidase_M17_N PF02789.17 PVD22364.1 - 0.025 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 PVD22364.1 - 0.034 13.7 3.5 1.3 8.6 0.0 3.2 3 1 0 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PVD22364.1 - 0.095 12.0 0.6 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 PVD22364.1 - 0.098 12.2 0.1 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 PVD22364.1 - 0.14 11.4 0.1 0.94 8.7 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PVD22364.1 - 0.15 10.7 0.4 2.8 6.6 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 PVD22364.1 - 0.29 10.2 0.1 8.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A PMT PF02366.18 PVD22365.1 - 1e-70 238.1 17.9 1e-70 238.1 17.9 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PVD22365.1 - 3.6e-57 193.2 10.0 3.6e-57 193.2 10.0 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 PVD22365.1 - 3.3e-16 59.7 0.3 6.1e-16 58.8 0.3 1.3 1 0 0 1 1 1 1 MIR domain Borrelia_P13 PF05628.12 PVD22365.1 - 0.087 12.8 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Borrelia membrane protein P13 Ribonucleas_3_3 PF14622.6 PVD22366.1 - 1.5e-38 131.9 0.0 5.8e-18 65.3 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PVD22366.1 - 1e-36 125.8 5.2 9e-21 74.5 0.1 4.4 3 1 0 3 3 3 2 Ribonuclease III domain dsrm PF00035.26 PVD22366.1 - 1e-11 45.4 0.0 3.4e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif IMUP PF15761.5 PVD22366.1 - 0.0047 17.6 7.2 0.0047 17.6 7.2 3.6 3 1 1 4 4 4 1 Immortalisation up-regulated protein C1q PF00386.21 PVD22367.1 - 5.1e-15 55.8 0.0 8.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 C1q domain DUF3573 PF12097.8 PVD22367.1 - 0.016 14.0 0.3 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) BBP1_C PF15272.6 PVD22367.1 - 0.037 13.8 0.2 0.076 12.8 0.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Spc29 PF17082.5 PVD22367.1 - 0.13 12.1 0.3 6.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 DivIC PF04977.15 PVD22367.1 - 0.23 11.3 3.9 9 6.2 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 PVD22367.1 - 0.28 11.7 4.4 12 6.4 1.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Gly_acyl_tr_N PF06021.11 PVD22367.1 - 0.29 11.2 2.6 19 5.3 0.2 2.9 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase SlyX PF04102.12 PVD22367.1 - 1.6 9.4 8.4 17 6.1 4.8 2.3 2 0 0 2 2 2 0 SlyX TolA_bind_tri PF16331.5 PVD22367.1 - 2.6 8.2 8.0 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation SSF PF00474.17 PVD22368.1 - 4.2e-136 454.0 19.8 5.2e-136 453.7 19.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3754 PF12576.8 PVD22368.1 - 0.17 11.8 0.3 0.44 10.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) SRCR PF00530.18 PVD22369.1 - 7.8e-39 132.2 12.7 1.6e-23 83.1 1.7 2.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 PVD22369.1 - 2.6e-27 96.3 7.0 5.5e-27 95.2 7.0 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 PVD22369.1 - 3e-10 40.5 1.0 0.00011 22.6 0.1 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22369.1 - 5.8e-05 23.6 0.4 0.16 12.5 0.1 3.0 2 0 0 2 2 2 2 Hepsin, SRCR domain LBP_BPI_CETP PF01273.25 PVD22369.1 - 0.019 14.6 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Y_phosphatase PF00102.27 PVD22370.1 - 2.1e-49 168.2 0.0 4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD22370.1 - 8.3e-32 109.4 29.0 3.6e-08 33.6 0.6 7.1 7 1 0 7 7 6 5 Fibronectin type III domain PTP_tm PF18861.1 PVD22370.1 - 3.9e-05 23.7 1.8 0.00024 21.2 0.6 2.7 2 1 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Pur_ac_phosph_N PF16656.5 PVD22370.1 - 0.00028 21.4 25.2 0.14 12.7 0.1 6.1 5 1 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain DUF2207 PF09972.9 PVD22370.1 - 0.0035 16.2 0.0 0.0087 14.9 0.0 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 PVD22370.1 - 0.007 16.3 0.5 0.017 15.0 0.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 PVD22370.1 - 0.0081 16.3 0.8 0.028 14.5 0.8 1.9 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 PVD22370.1 - 0.0086 16.9 0.0 0.016 16.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 PVD22370.1 - 0.01 14.3 0.2 0.016 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DSPc PF00782.20 PVD22370.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Adeno_E3_CR2 PF02439.15 PVD22370.1 - 0.025 14.3 8.4 0.066 13.0 8.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 PVD22370.1 - 0.042 13.8 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.11 PVD22370.1 - 0.051 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Mid2 PF04478.12 PVD22370.1 - 0.074 12.9 0.9 0.15 11.8 0.9 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Stevor PF17410.2 PVD22370.1 - 0.11 12.0 0.5 0.31 10.6 0.2 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Y_phosphatase3 PF13350.6 PVD22370.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4690 PF15756.5 PVD22370.1 - 0.13 12.9 4.4 12 6.6 0.2 3.8 4 0 0 4 4 3 0 Small Novel Rich in Cartilage RIFIN PF02009.16 PVD22370.1 - 0.21 11.4 0.3 0.38 10.6 0.3 1.3 1 0 0 1 1 1 0 Rifin SKG6 PF08693.10 PVD22370.1 - 0.3 10.5 7.8 0.72 9.3 7.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Y_phosphatase PF00102.27 PVD22371.1 - 5.9e-58 196.2 6.0 4.8e-53 180.2 0.4 2.8 2 1 1 3 3 3 2 Protein-tyrosine phosphatase SM-ATX PF14438.6 PVD22371.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain SRCR PF00530.18 PVD22372.1 - 1.3e-45 154.0 7.4 6.4e-26 90.8 1.1 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 PVD22372.1 - 4.9e-24 85.5 1.0 7.3e-24 84.9 1.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 PVD22372.1 - 9.7e-09 35.7 5.4 0.0018 18.8 0.6 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD22372.1 - 0.0017 18.8 0.1 0.24 11.9 0.1 2.6 2 0 0 2 2 2 1 Hepsin, SRCR domain TraQ PF09679.10 PVD22373.1 - 0.04 13.8 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Rieske PF00355.26 PVD22374.1 - 2e-15 56.5 0.2 3.6e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PVD22374.1 - 2.5e-05 24.1 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain PBC PF03792.13 PVD22375.1 - 7.9e-94 312.7 0.9 1.3e-93 312.0 0.9 1.4 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 PVD22375.1 - 4.5e-34 116.1 3.7 1e-18 66.9 0.8 2.5 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 PVD22375.1 - 1.6e-29 101.5 0.0 2.1e-15 56.3 0.0 2.9 3 0 0 3 3 2 2 Homeobox KN domain YdaS_antitoxin PF15943.5 PVD22375.1 - 5.7e-08 32.5 0.1 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 PVD22375.1 - 2.7e-06 27.3 0.2 0.022 14.8 0.0 2.8 3 0 0 3 3 2 2 Helix-turn-helix HTH_23 PF13384.6 PVD22375.1 - 3.4e-06 26.7 0.3 0.15 11.9 0.1 2.9 2 0 0 2 2 2 2 Homeodomain-like domain HTH_26 PF13443.6 PVD22375.1 - 3.4e-05 24.2 0.0 0.2 12.1 0.0 3.0 3 0 0 3 3 3 2 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.13 PVD22375.1 - 0.00015 21.3 0.0 0.36 10.5 0.0 2.7 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 PVD22375.1 - 0.0028 17.8 0.0 4.6 7.5 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain MerR_1 PF13411.6 PVD22375.1 - 0.0045 17.0 0.1 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_31 PF13560.6 PVD22375.1 - 0.011 16.0 0.8 7.1 7.1 0.0 3.3 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 PVD22375.1 - 0.019 14.9 0.0 9.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.6 PVD22375.1 - 0.022 14.3 0.2 7.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sec15 PF04091.12 PVD22375.1 - 0.026 13.9 0.3 0.046 13.1 0.3 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Phage_CI_repr PF07022.13 PVD22375.1 - 0.03 14.4 0.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Homez PF11569.8 PVD22375.1 - 0.047 13.2 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DprA_WH PF17782.1 PVD22375.1 - 0.063 13.4 0.2 18 5.5 0.0 3.0 3 0 0 3 3 3 0 DprA winged helix domain HTH_17 PF12728.7 PVD22375.1 - 0.12 12.6 0.5 5.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 PVD22375.1 - 0.13 12.1 0.0 27 4.6 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein Con-6 PF10346.9 PVD22375.1 - 0.15 12.1 0.6 11 6.2 0.1 2.8 2 0 0 2 2 2 0 Conidiation protein 6 HTH_19 PF12844.7 PVD22375.1 - 0.31 11.1 2.2 2.5 8.2 0.1 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain Ribosomal_60s PF00428.19 PVD22375.1 - 0.54 10.9 6.8 4 8.1 1.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hydrolase PF00702.26 PVD22376.1 - 3.7e-15 56.8 0.0 4.4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PVD22376.1 - 2.6e-14 53.1 0.0 6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 PVD22376.1 - 6.6e-06 26.1 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PVD22376.1 - 0.0025 17.6 0.0 0.082 12.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FRG2 PF15315.6 PVD22376.1 - 0.04 14.1 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Claudin_3 PF06653.11 PVD22376.1 - 3.4 7.6 12.2 0.11 12.5 0.3 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like DUF5054 PF16477.5 PVD22377.1 - 4.1e-24 85.8 0.0 1.3e-23 84.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) RVT_1 PF00078.27 PVD22378.1 - 4.9e-17 62.2 0.0 2e-16 60.2 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PVD22378.1 - 0.00056 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PVD22378.1 - 0.00068 20.1 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C3HC4_3 PF13920.6 PVD22379.1 - 6.5e-11 41.9 15.4 1.6e-10 40.7 12.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.6 PVD22379.1 - 1.8e-09 37.2 20.1 0.00013 21.7 8.0 3.1 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PVD22379.1 - 1.9e-07 31.3 20.1 8.5e-05 22.9 5.7 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) SAM_2 PF07647.17 PVD22379.1 - 1.3e-06 28.4 1.6 5e-06 26.5 0.0 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD22379.1 - 2.3e-05 24.8 0.4 0.00016 22.0 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LRR_9 PF14580.6 PVD22379.1 - 3.5e-05 23.4 5.9 0.00014 21.4 5.9 1.9 1 1 0 1 1 1 1 Leucine-rich repeat Prok-RING_4 PF14447.6 PVD22379.1 - 0.0033 17.3 12.1 0.0073 16.1 12.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD22379.1 - 0.11 12.4 14.5 0.24 11.3 14.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TraH PF06122.11 PVD22379.1 - 0.63 9.2 4.2 1.1 8.5 4.2 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF763 PF05559.11 PVD22379.1 - 2.5 7.2 8.9 3.7 6.6 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF763) zf-RING_11 PF17123.5 PVD22379.1 - 2.7 7.8 11.7 0.051 13.3 2.1 2.7 2 0 0 2 2 2 0 RING-like zinc finger VWA PF00092.28 PVD22380.1 - 1.6e-39 136.0 2.1 2.3e-39 135.4 2.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD22380.1 - 1.8e-18 67.1 0.4 3.5e-18 66.2 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD22380.1 - 1e-05 25.6 0.7 2.2e-05 24.5 0.7 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PVD22380.1 - 0.015 14.5 2.2 0.04 13.1 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1194) zf-C4 PF00105.18 PVD22382.1 - 2.4e-31 108.0 12.1 4.6e-31 107.1 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD22382.1 - 3.3e-29 102.0 6.9 8.5e-29 100.6 6.9 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Homeodomain PF00046.29 PVD22385.1 - 2.6e-09 36.8 10.9 3.7e-06 26.7 0.3 2.3 1 1 1 2 2 2 2 Homeodomain OAR PF03826.17 PVD22385.1 - 0.00016 21.4 0.1 0.00057 19.6 0.0 2.0 2 0 0 2 2 2 1 OAR domain PROL5-SMR PF15621.6 PVD22385.1 - 0.066 13.7 1.3 0.11 13.0 1.3 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family CBM_14 PF01607.24 PVD22386.1 - 1.3e-14 54.1 13.1 4.3e-12 46.0 3.3 2.8 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain DUF2724 PF10893.8 PVD22386.1 - 0.073 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) CBM_14 PF01607.24 PVD22387.1 - 4.3e-16 58.8 14.0 2.2e-11 43.7 5.6 2.6 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD22388.1 - 5.9e-14 52.0 16.0 1.2e-08 35.0 4.6 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain SSF PF00474.17 PVD22390.1 - 4e-116 388.2 19.8 5.3e-116 387.8 19.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2569 PF10754.9 PVD22390.1 - 0.0058 17.1 3.1 0.0058 17.1 3.1 4.0 4 1 0 4 4 4 1 Protein of unknown function (DUF2569) DUF1647 PF07801.11 PVD22391.1 - 1.5e-10 41.0 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) 7TM_GPCR_Srw PF10324.9 PVD22392.1 - 0.021 14.1 0.5 0.021 14.1 0.5 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw TRI12 PF06609.13 PVD22393.1 - 0.0086 14.5 0.3 0.012 14.0 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 7TM_GPCR_Srw PF10324.9 PVD22393.1 - 0.031 13.6 0.7 0.031 13.6 0.7 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Claudin_2 PF13903.6 PVD22393.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 7TM_GPCR_Srx PF10328.9 PVD22394.1 - 0.0051 16.5 10.4 0.0083 15.8 10.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ORC3_N PF07034.11 PVD22394.1 - 0.16 11.1 0.4 0.34 10.0 0.4 1.6 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus FAM176 PF14851.6 PVD22394.1 - 1.4 8.6 3.5 2.7 7.7 3.5 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 PVD22394.1 - 8 6.9 9.4 13 6.2 8.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain 7TM_GPCR_Srx PF10328.9 PVD22395.1 - 0.086 12.5 12.6 0.15 11.7 12.6 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx EF-hand_7 PF13499.6 PVD22396.1 - 1.4e-07 31.9 1.9 0.004 17.6 0.4 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD22396.1 - 1.2e-06 27.6 6.8 0.14 11.7 1.7 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD22396.1 - 0.00036 20.2 3.8 2.6 8.2 0.9 4.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 PVD22396.1 - 0.00041 19.7 9.6 1.9 8.1 0.0 4.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD22396.1 - 0.0073 16.1 1.5 0.79 9.6 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair Dockerin_1 PF00404.18 PVD22396.1 - 0.087 13.0 0.2 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain Hormone_recep PF00104.30 PVD22397.1 - 4.3e-40 137.5 0.0 8.1e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD22397.1 - 7.9e-31 106.3 17.2 1.4e-30 105.6 17.2 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Tubulin_C PF03953.17 PVD22397.1 - 0.019 15.1 0.2 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Tubulin C-terminal domain Mito_fiss_reg PF05308.11 PVD22399.1 - 0.25 11.4 4.6 0.23 11.5 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator ACBP PF00887.19 PVD22400.1 - 2.4e-24 85.4 0.2 5.8e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_2 PF12796.7 PVD22400.1 - 1.6e-16 60.6 0.0 8.1e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22400.1 - 1.6e-16 60.1 1.4 7.7e-09 35.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD22400.1 - 6.2e-14 52.2 0.3 8.6e-12 45.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD22400.1 - 9.4e-13 48.0 0.0 4.2e-05 23.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD22400.1 - 1.7e-10 40.2 0.0 0.0029 18.0 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat PLA2_B PF01735.18 PVD22403.1 - 5.2e-82 275.8 0.0 7.1e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 PVD22403.1 - 2.2e-10 40.8 0.1 4.8e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain Patatin PF01734.22 PVD22403.1 - 0.005 17.0 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase Treacle PF03546.14 PVD22403.1 - 0.014 14.2 0.9 0.02 13.7 0.9 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DUF1054 PF06335.12 PVD22403.1 - 0.034 14.1 0.4 0.069 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) An_peroxidase PF03098.15 PVD22404.1 - 6.7e-29 100.8 0.0 7.7e-25 87.5 0.0 2.0 2 0 0 2 2 2 2 Animal haem peroxidase EGF PF00008.27 PVD22404.1 - 0.0061 16.8 10.6 0.013 15.8 10.6 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 PVD22404.1 - 0.0086 16.4 8.0 0.016 15.6 8.0 1.4 1 0 0 1 1 1 1 EGF-like domain FtsJ PF01728.19 PVD22405.1 - 1.4e-28 100.2 0.1 7e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 PVD22405.1 - 0.083 10.9 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase zf-C4 PF00105.18 PVD22406.1 - 9.4e-29 99.7 12.6 1.8e-28 98.8 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD22406.1 - 9.5e-28 97.2 0.1 1.9e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Myb_DNA-binding PF00249.31 PVD22407.1 - 5.3e-10 39.3 0.6 1.1e-09 38.3 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 PVD22407.1 - 6.4e-07 29.1 8.1 1.2e-06 28.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 PVD22407.1 - 0.00021 21.5 1.5 0.00034 20.8 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain PolC_DP2 PF03833.13 PVD22407.1 - 2.3 6.0 5.2 0.82 7.5 2.7 1.4 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 OST3_OST6 PF04756.13 PVD22408.1 - 1.2e-10 41.2 0.2 1.3e-10 41.1 0.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF5054 PF16477.5 PVD22409.1 - 5.9e-26 91.9 0.0 1.5e-25 90.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) MADF_DNA_bdg PF10545.9 PVD22410.1 - 1.5e-14 54.1 1.1 1.5e-14 54.1 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 PVD22410.1 - 2.9e-05 24.4 0.3 7.8e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BCDHK_Adom3 PF10436.9 PVD22410.1 - 0.047 13.5 1.6 0.067 13.0 1.6 1.4 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TssO PF17561.2 PVD22410.1 - 0.052 13.7 0.6 0.14 12.3 0.4 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF573 PF04504.14 PVD22410.1 - 0.27 11.9 4.3 0.94 10.2 0.1 2.8 2 2 1 3 3 3 0 Protein of unknown function, DUF573 DUF5054 PF16477.5 PVD22411.1 - 5e-28 98.7 0.0 1.5e-27 97.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) Pkinase PF00069.25 PVD22412.1 - 6.1e-06 25.8 0.0 8.2e-05 22.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22412.1 - 6.8e-06 25.6 0.0 9.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PIP5K PF01504.18 PVD22413.1 - 6.2e-61 206.0 0.1 1.2e-60 205.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_1 PF00001.21 PVD22414.1 - 1.4e-45 155.7 6.2 1.8e-45 155.3 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD22414.1 - 2.5e-06 27.1 13.9 5.4e-06 26.0 13.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD22414.1 - 2.8e-05 24.0 8.3 2.8e-05 24.0 8.3 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 PVD22414.1 - 0.29 10.4 10.2 0.5 9.6 10.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Mycoplasma_p37 PF06646.11 PVD22415.1 - 0.12 11.6 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 High affinity transport system protein p37 Rhomboid PF01694.22 PVD22416.1 - 3.4e-33 114.8 9.5 3.4e-33 114.8 9.5 2.1 3 0 0 3 3 3 1 Rhomboid family EF-hand_1 PF00036.32 PVD22416.1 - 0.00012 21.4 0.1 0.00031 20.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PVD22416.1 - 0.00092 19.6 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD22416.1 - 0.092 12.7 0.5 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain Cas9_a PF18470.1 PVD22416.1 - 0.1 12.1 0.3 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain EF-hand_8 PF13833.6 PVD22416.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Trm112p PF03966.16 PVD22417.1 - 1.5e-18 67.1 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Sigma70_ner PF04546.13 PVD22418.1 - 0.42 10.4 14.3 1.6 8.6 14.3 2.0 1 0 0 1 1 1 0 Sigma-70, non-essential region tRNA-synt_2 PF00152.20 PVD22419.1 - 1.3e-95 320.2 0.1 1.5e-95 319.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 PVD22419.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 PVD22419.1 - 0.019 14.5 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RTX_C PF08339.10 PVD22419.1 - 0.043 13.9 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain tRNA-synt_2b PF00587.25 PVD22419.1 - 0.16 12.0 0.1 1.7 8.6 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Iso_dh PF00180.20 PVD22420.1 - 3.4e-52 177.7 0.1 1e-38 133.4 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Arf PF00025.21 PVD22421.1 - 9.7e-71 236.8 0.1 1.1e-70 236.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PVD22421.1 - 7.9e-14 51.9 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PVD22421.1 - 2.6e-13 49.9 0.4 1.2e-07 31.2 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PVD22421.1 - 4.3e-13 49.1 0.0 5.1e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PVD22421.1 - 8.5e-13 48.2 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 PVD22421.1 - 3.4e-12 46.2 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PVD22421.1 - 2e-08 34.3 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD22421.1 - 1.5e-05 24.6 0.1 0.00072 19.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 PVD22421.1 - 0.0006 20.3 0.0 0.00084 19.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 PVD22421.1 - 0.0011 18.0 0.1 0.12 11.4 0.1 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PVD22421.1 - 0.01 15.7 0.1 3.3 7.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 PVD22421.1 - 0.015 15.9 0.0 0.032 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 PVD22421.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 PVD22421.1 - 0.022 14.3 0.2 0.19 11.2 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 PVD22421.1 - 0.03 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 PVD22421.1 - 0.042 13.8 0.0 6.9 6.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 PVD22421.1 - 0.047 13.7 0.0 0.18 11.9 0.0 1.7 1 1 0 2 2 2 0 AAA domain cobW PF02492.19 PVD22421.1 - 0.066 12.8 0.2 7.9 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PVD22421.1 - 0.075 13.4 0.1 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PVD22421.1 - 0.079 13.2 0.1 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PVD22421.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 NTPase LIM PF00412.22 PVD22422.1 - 1.3e-32 111.7 18.9 9.5e-18 64.2 3.1 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 PVD22422.1 - 1.6e-20 72.7 3.0 3.2e-20 71.7 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD22422.1 - 0.0025 17.7 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain C1_1 PF00130.22 PVD22422.1 - 0.3 11.0 15.3 0.97 9.4 6.2 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_14 PF17978.1 PVD22422.1 - 1.3 9.5 8.4 2.5 8.6 0.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Furin-like_2 PF15913.5 PVD22422.1 - 1.7 8.8 14.6 0.076 13.2 8.3 2.0 1 1 0 1 1 1 0 Furin-like repeat, cysteine-rich DUF4762 PF15959.5 PVD22423.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Pkinase PF00069.25 PVD22424.1 - 9.3e-68 228.4 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22424.1 - 3e-32 111.9 0.0 3.9e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD22424.1 - 0.00013 21.0 0.3 0.00026 20.0 0.3 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD22424.1 - 0.0013 18.1 0.1 0.0062 15.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PVD22424.1 - 0.055 12.8 0.3 0.096 12.0 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PVD22424.1 - 0.057 12.2 0.3 0.11 11.3 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase GFA PF04828.14 PVD22425.1 - 0.0073 16.6 0.1 0.11 12.8 0.0 2.4 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme GCSF PF16647.5 PVD22425.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor PID PF00640.23 PVD22426.1 - 1.2e-20 73.9 1.5 2e-19 70.0 0.6 2.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SIN1_PH PF16979.5 PVD22426.1 - 0.00021 21.5 1.2 0.0005 20.3 1.2 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology VirE_N PF08800.10 PVD22426.1 - 0.1 12.7 0.1 0.93 9.6 0.0 2.3 1 1 1 2 2 2 0 VirE N-terminal domain APH PF01636.23 PVD22427.1 - 2.3e-14 53.9 0.0 3.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PVD22427.1 - 0.012 15.3 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family zf-RING_UBOX PF13445.6 PVD22428.1 - 9.8e-12 44.7 6.7 2.2e-11 43.6 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD22428.1 - 5.3e-11 42.2 7.9 5.3e-11 42.2 7.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22428.1 - 8.7e-11 41.8 8.0 8.7e-11 41.8 8.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD22428.1 - 1.4e-10 40.9 8.9 3.3e-10 39.7 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22428.1 - 2e-10 40.8 8.6 2e-10 40.8 8.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22428.1 - 3.3e-10 39.7 5.2 3.3e-10 39.7 5.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22428.1 - 5.1e-08 32.6 7.4 5.1e-08 32.6 7.4 2.9 2 2 2 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD22428.1 - 1.4e-05 25.0 5.6 1.4e-05 25.0 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 PVD22428.1 - 0.00016 21.8 0.4 0.00037 20.6 0.1 1.8 2 0 0 2 2 1 1 U-box domain zf-RING_10 PF16685.5 PVD22428.1 - 0.00091 19.3 6.7 0.0058 16.7 2.6 2.6 1 1 1 2 2 2 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PVD22428.1 - 0.0011 19.0 1.3 0.0011 19.0 1.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PVD22428.1 - 0.009 16.3 8.3 0.063 13.6 8.3 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 PVD22428.1 - 0.012 15.4 4.2 0.022 14.5 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Med30 PF11315.8 PVD22428.1 - 0.028 14.6 0.5 0.045 14.0 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 TerB_C PF15615.6 PVD22428.1 - 0.094 13.0 1.5 0.14 12.5 1.5 1.2 1 0 0 1 1 1 0 TerB-C domain EAP30 PF04157.16 PVD22428.1 - 0.36 10.1 2.8 0.56 9.4 2.8 1.4 1 1 0 1 1 1 0 EAP30/Vps36 family IBR PF01485.21 PVD22428.1 - 0.53 10.6 5.3 3.8 7.8 0.1 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain RINGv PF12906.7 PVD22428.1 - 1 9.5 7.3 4.3 7.5 7.3 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 PVD22428.1 - 1.2 9.0 14.2 0.04 13.7 7.1 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2HC5 PF06221.13 PVD22428.1 - 9.2 6.3 10.4 5.1 7.2 4.7 2.8 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type SRF-TF PF00319.18 PVD22429.1 - 0.051 13.1 2.3 0.082 12.4 2.3 1.3 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Tau95 PF09734.9 PVD22430.1 - 4.7e-39 134.4 1.2 1.6e-38 132.7 0.8 2.3 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 PVD22430.1 - 1.3e-32 112.7 0.0 4.1e-32 111.0 0.0 2.0 1 0 0 1 1 1 1 Tau95 Triple barrel domain VPS9 PF02204.18 PVD22430.1 - 1.9e-26 92.3 1.4 3.9e-26 91.3 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 PVD22430.1 - 1.1e-18 67.7 0.1 3.5e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF5601 PF18151.1 PVD22430.1 - 1.2e-10 41.5 4.1 3.2e-10 40.2 2.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) TFIIF_beta PF02270.15 PVD22430.1 - 0.026 14.7 0.1 0.077 13.2 0.1 1.7 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Band_7 PF01145.25 PVD22431.1 - 5.9e-33 114.3 1.5 8e-33 113.9 1.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 PVD22431.1 - 0.0019 17.9 0.2 0.0028 17.4 0.2 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 PVD22431.1 - 0.099 13.1 0.6 0.26 11.7 0.5 1.8 1 1 0 1 1 1 0 Phage protein Gp68 Band_7 PF01145.25 PVD22432.1 - 8.4e-20 71.5 7.2 4.9e-19 69.0 0.1 2.1 1 1 1 2 2 2 2 SPFH domain / Band 7 family CdiI PF07262.11 PVD22432.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 CDI immunity protein Baculo_PEP_C PF04513.12 PVD22433.1 - 1.7e-13 50.8 40.2 0.0026 17.8 4.9 6.8 3 1 6 9 9 9 7 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 PVD22433.1 - 6.4e-08 32.7 6.8 1.8 8.7 0.2 6.8 2 1 5 8 8 8 3 Domain of unknown function DUF148 Apolipoprotein PF01442.18 PVD22433.1 - 4.2e-07 30.0 0.0 0.054 13.4 0.0 3.2 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 PVD22433.1 - 7.6e-06 26.1 29.1 0.032 14.3 1.0 5.5 1 1 4 5 5 5 4 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.11 PVD22433.1 - 9.9e-06 25.7 1.4 36 4.4 0.0 6.9 1 1 7 9 9 9 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4088 PF13317.6 PVD22433.1 - 2.6 7.6 24.6 15 5.1 0.6 6.5 1 1 3 6 6 6 0 Protein of unknown function (DUF4088) QVR PF17064.5 PVD22434.1 - 0.059 13.6 3.3 0.15 12.3 3.3 1.7 1 0 0 1 1 1 0 Sleepless protein Golgin_A5 PF09787.9 PVD22435.1 - 0.0017 17.9 7.4 0.004 16.7 7.4 1.7 1 0 0 1 1 1 1 Golgin subfamily A member 5 KLRAQ PF10205.9 PVD22435.1 - 0.0046 17.2 6.3 0.25 11.6 0.6 3.0 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein DUF148 PF02520.17 PVD22435.1 - 0.014 15.5 4.2 0.014 15.5 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF4407 PF14362.6 PVD22435.1 - 0.5 9.7 4.4 0.79 9.0 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XLF PF09302.11 PVD22435.1 - 4.5 7.4 8.7 0.53 10.4 1.2 2.6 3 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component OmpH PF03938.14 PVD22435.1 - 6.1 7.2 8.5 1 9.7 4.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3498 PF12004.8 PVD22436.1 - 2.5e-35 122.7 69.1 2.5e-35 122.7 69.1 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3498) RasGAP PF00616.19 PVD22436.1 - 2.6e-26 92.6 8.8 3.7e-15 56.2 0.5 3.6 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 PVD22436.1 - 0.0036 17.8 0.1 0.037 14.5 0.1 2.7 2 0 0 2 2 2 1 PH domain C2 PF00168.30 PVD22436.1 - 0.011 16.0 0.2 0.025 14.9 0.2 1.6 1 0 0 1 1 1 0 C2 domain Golgin_A5 PF09787.9 PVD22436.1 - 0.52 9.7 26.0 1.4 8.3 26.0 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 Dna2 PF08696.11 PVD22436.1 - 1.7 8.4 9.8 4.3 7.1 9.8 1.7 1 0 0 1 1 1 0 DNA replication factor Dna2 Exonuc_VII_L PF02601.15 PVD22436.1 - 1.9 8.0 15.6 13 5.2 16.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit GST_C_3 PF14497.6 PVD22438.1 - 5.2e-15 55.4 0.0 6.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD22438.1 - 3.5e-07 30.3 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD22438.1 - 0.017 15.1 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PVD22438.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4031 PF13223.6 PVD22439.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Rap_GAP PF02145.15 PVD22442.1 - 5.9e-63 211.8 0.2 9e-63 211.2 0.2 1.3 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 PVD22442.1 - 7.1e-41 140.6 0.0 9.4e-26 91.0 0.0 2.5 2 1 1 3 3 3 2 CNH domain Ank_2 PF12796.7 PVD22443.1 - 2.3e-21 76.2 0.6 1.3e-10 41.7 0.1 3.5 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD22443.1 - 2.8e-21 75.6 5.5 8.6e-08 32.6 0.1 6.0 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD22443.1 - 2.1e-16 58.4 3.6 0.00012 22.3 0.1 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PVD22443.1 - 6.7e-13 48.5 9.4 8.6e-06 26.0 0.5 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 PVD22443.1 - 9e-12 45.0 3.6 0.0051 17.1 0.1 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) zf-MYND PF01753.18 PVD22443.1 - 3.1e-10 39.9 4.9 3.1e-10 39.9 4.9 3.5 5 0 0 5 5 5 1 MYND finger Amidase_6 PF12671.7 PVD22443.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative amidase domain CC190 PF15768.5 PVD22444.1 - 1.6e-05 25.1 0.2 1.9e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 190 G_path_suppress PF15991.5 PVD22444.1 - 0.11 12.7 0.7 0.11 12.6 0.7 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor CMD PF02627.20 PVD22445.1 - 1.5e-12 47.3 0.7 5.2e-12 45.7 0.3 1.9 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family Siah-Interact_N PF09032.11 PVD22446.1 - 3e-12 46.7 4.3 4.7e-12 46.0 0.6 2.5 2 0 0 2 2 2 1 Siah interacting protein, N terminal CS PF04969.16 PVD22446.1 - 6.2e-11 43.2 0.3 1e-10 42.5 0.3 1.4 1 0 0 1 1 1 1 CS domain SGS PF05002.15 PVD22446.1 - 5.6e-05 23.2 3.7 0.00013 22.0 3.7 1.6 1 0 0 1 1 1 1 SGS domain DUF3243 PF11588.8 PVD22446.1 - 0.069 13.5 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) EGF PF00008.27 PVD22447.1 - 8.6e-208 671.8 575.7 4.6e-08 33.2 9.7 37.2 37 0 0 37 37 36 35 EGF-like domain hEGF PF12661.7 PVD22447.1 - 9.7e-130 419.4 489.2 4.2e-07 30.3 8.5 37.8 37 0 0 37 37 35 34 Human growth factor-like EGF EGF_CA PF07645.15 PVD22447.1 - 4e-65 215.8 562.7 3.8e-07 30.2 11.9 36.4 21 9 15 36 36 35 23 Calcium-binding EGF domain EGF_2 PF07974.13 PVD22447.1 - 6.2e-31 106.5 668.8 0.0027 18.1 8.9 38.4 38 0 0 38 38 36 28 EGF-like domain Ank_2 PF12796.7 PVD22447.1 - 4.1e-29 101.0 9.5 2.1e-11 44.2 2.1 4.4 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22447.1 - 1.9e-26 91.7 8.3 8.3e-10 38.7 0.1 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD22447.1 - 2.6e-23 81.4 11.6 0.0025 18.2 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Notch PF00066.17 PVD22447.1 - 7.1e-23 80.8 43.6 4.3e-11 43.1 8.4 20.2 20 7 6 26 26 5 3 LNR domain NOD PF06816.13 PVD22447.1 - 6.1e-21 73.8 0.1 9.7e-21 73.2 0.1 1.3 1 0 0 1 1 1 1 NOTCH protein DUF3454 PF11936.8 PVD22447.1 - 1.1e-19 70.6 22.8 1.1e-19 70.6 22.8 2.8 2 0 0 2 2 1 1 Domain of unknown function (DUF3454) Ank_4 PF13637.6 PVD22447.1 - 5.4e-16 58.7 1.2 0.0018 18.8 0.1 6.0 3 1 4 7 7 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD22447.1 - 1.1e-15 56.1 2.6 0.00052 20.3 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat NODP PF07684.12 PVD22447.1 - 9.5e-14 51.3 0.0 1.3e-12 47.6 0.0 3.3 1 0 0 1 1 1 1 NOTCH protein cEGF PF12662.7 PVD22447.1 - 7.1e-05 22.7 13.7 0.00015 21.6 3.2 36.3 38 1 0 38 38 33 16 Complement Clr-like EGF-like LAP1C PF05609.12 PVD22448.1 - 2.7e-21 76.2 5.3 4.5e-21 75.5 5.3 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) GldM_N PF12081.8 PVD22448.1 - 0.045 13.8 4.2 0.11 12.6 0.6 2.8 2 1 0 2 2 2 0 GldM N-terminal domain MFS_1 PF07690.16 PVD22448.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily RRM_1 PF00076.22 PVD22449.1 - 2.6e-55 184.2 0.0 1.1e-17 63.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD22449.1 - 3.9e-11 42.6 0.0 4.6e-07 29.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD22449.1 - 0.0055 16.5 0.0 0.31 10.9 0.0 2.7 2 1 0 2 2 2 1 Occluded RNA-recognition motif RNA_bind PF08675.11 PVD22449.1 - 0.036 14.1 0.1 3.4 7.7 0.0 2.7 2 2 0 2 2 2 0 RNA binding domain zf-H2C2_5 PF13909.6 PVD22450.1 - 1.3 8.8 5.5 6 6.7 5.5 2.3 1 0 0 1 1 1 0 C2H2-type zinc-finger domain UNC80 PF15778.5 PVD22451.1 - 2.2e-11 43.7 0.0 4.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Cation channel complex component UNC80 DUF3038 PF11237.8 PVD22451.1 - 0.087 12.9 0.2 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) OST-HTH PF12872.7 PVD22452.1 - 8.1e-44 147.3 1.3 1.5e-10 40.7 0.0 4.6 4 0 0 4 4 4 4 OST-HTH/LOTUS domain TUDOR PF00567.24 PVD22452.1 - 2.1e-21 76.2 0.0 4.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Tudor domain CLZ PF16526.5 PVD22452.1 - 0.39 11.1 3.2 3.8 7.9 0.5 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_12 PF13424.6 PVD22453.1 - 3.5e-16 59.2 9.2 2.7e-09 37.2 0.6 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD22453.1 - 1.5e-11 43.4 4.5 0.058 13.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD22453.1 - 2.1e-11 43.8 7.4 2.6e-06 27.1 1.1 2.0 1 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 PVD22453.1 - 2.5e-10 39.7 4.3 0.013 15.3 0.1 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD22453.1 - 3.4e-08 33.1 5.4 0.016 15.1 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22453.1 - 1.6e-06 28.5 10.5 0.0054 17.2 0.4 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD22453.1 - 1.8e-06 28.3 3.1 0.74 10.8 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22453.1 - 2.2e-06 27.4 6.4 2.7 8.4 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22453.1 - 4.8e-06 27.1 1.3 0.085 13.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD22453.1 - 0.00014 21.7 2.7 5.6 7.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22453.1 - 0.0016 18.0 0.5 0.13 12.0 0.0 3.7 3 1 0 3 3 3 1 TPR repeat RPN7 PF10602.9 PVD22453.1 - 0.0078 15.9 5.7 0.87 9.3 0.6 2.7 2 1 0 2 2 2 2 26S proteasome subunit RPN7 ANAPC5 PF12862.7 PVD22453.1 - 0.057 13.5 2.5 1 9.5 0.1 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Lectin_leg-like PF03388.13 PVD22453.1 - 0.13 11.6 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Legume-like lectin family ANAPC3 PF12895.7 PVD22453.1 - 1.8 8.9 7.1 0.76 10.0 0.2 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Zip PF02535.22 PVD22454.1 - 5.1e-76 256.1 15.7 5.1e-76 256.1 15.7 3.9 2 2 0 2 2 2 1 ZIP Zinc transporter Presenilin PF01080.17 PVD22454.1 - 0.036 12.8 0.0 0.036 12.8 0.0 2.4 2 0 0 2 2 2 0 Presenilin DUF913 PF06025.12 PVD22454.1 - 0.089 11.8 0.2 0.19 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP-gamma PF07074.12 PVD22454.1 - 0.25 10.9 0.6 0.47 10.0 0.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SLC12 PF03522.15 PVD22454.1 - 0.4 9.6 7.8 0.17 10.9 2.8 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Pox_Ag35 PF03286.14 PVD22454.1 - 4.6 7.0 14.5 11 5.7 14.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_M1 PF01433.20 PVD22455.1 - 2.7e-49 167.7 0.0 4.7e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PVD22455.1 - 3.3e-29 101.3 0.2 6.5e-29 100.3 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PVD22455.1 - 1e-19 71.5 0.0 2.9e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SPASM PF13186.6 PVD22455.1 - 0.19 12.3 0.1 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain DUF1859 PF08948.10 PVD22455.1 - 0.2 11.6 0.2 0.87 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1859) DNA_pol_A_exo1 PF01612.20 PVD22456.1 - 2.9e-23 82.5 0.1 7.6e-23 81.1 0.1 1.8 1 0 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.16 PVD22456.1 - 4.5e-23 82.0 1.2 1.6e-13 51.0 0.0 2.8 3 0 0 3 3 3 2 Mut7-C RNAse domain PP1_inhibitor PF05361.12 PVD22456.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor C1q PF00386.21 PVD22457.1 - 2.8e-18 66.4 0.1 4.4e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 C1q domain Rootletin PF15035.6 PVD22457.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 PVD22457.1 - 0.033 14.2 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 PVD22457.1 - 0.24 12.1 0.4 0.4 11.3 0.4 1.3 1 0 0 1 1 1 0 SlyX GP41 PF00517.17 PVD22457.1 - 0.59 10.0 4.5 0.2 11.6 0.5 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Lipocalin_7 PF14651.6 PVD22458.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PIP5K PF01504.18 PVD22459.1 - 2.1e-60 204.3 0.0 4.3e-60 203.3 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Tfb2 PF03849.14 PVD22460.1 - 6.2e-114 380.7 0.0 7.7e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PVD22460.1 - 1.7e-27 95.6 1.0 3.4e-27 94.7 1.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PVD22460.1 - 5.7e-05 23.3 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 PVD22461.1 - 4.4e-15 55.8 9.0 0.0085 16.9 0.0 6.8 7 0 0 7 7 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 PVD22461.1 - 1.5e-13 50.3 11.0 1.5e-13 50.3 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD22461.1 - 1.6e-10 40.7 11.8 5.8e-10 38.9 11.8 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22461.1 - 9.5e-09 35.5 9.8 4.2e-08 33.4 9.8 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD22461.1 - 2.5e-08 33.6 8.6 7e-08 32.2 8.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD22461.1 - 7.7e-08 32.2 8.0 7.7e-08 32.2 8.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22461.1 - 1.7e-07 31.0 10.9 1.7e-07 31.0 10.9 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD22461.1 - 7.6e-06 26.0 10.0 2.4e-05 24.4 10.0 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING WD40_like PF17005.5 PVD22461.1 - 1.2e-05 24.8 0.2 2.3e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 PVD22461.1 - 2.9e-05 24.3 0.5 0.36 11.2 0.0 3.8 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 PVD22461.1 - 0.0047 17.2 9.8 0.0047 17.2 9.8 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 PVD22461.1 - 0.0051 16.7 8.9 0.028 14.3 9.0 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 BAR_2 PF10455.9 PVD22461.1 - 0.0078 15.4 1.7 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-RING_4 PF14570.6 PVD22461.1 - 0.012 15.4 9.2 0.033 14.0 9.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 PVD22461.1 - 0.017 15.3 4.6 0.046 13.9 4.6 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 RNase_H_2 PF13482.6 PVD22461.1 - 0.044 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 RNase_H superfamily DZR PF12773.7 PVD22461.1 - 0.082 12.9 5.9 0.31 11.1 5.9 2.1 1 0 0 1 1 1 0 Double zinc ribbon bZIP_1 PF00170.21 PVD22461.1 - 0.19 11.9 1.3 0.83 9.8 1.3 2.1 1 0 0 1 1 1 0 bZIP transcription factor zf_C2H2_10 PF18414.1 PVD22461.1 - 0.28 10.8 2.1 2.1 7.9 0.5 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-P11 PF03854.14 PVD22461.1 - 0.54 10.0 7.6 1.6 8.4 7.6 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 PVD22461.1 - 5.1 7.2 9.6 2.6 8.2 3.5 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 PVD22461.1 - 5.6 6.9 7.5 5.7 6.8 5.3 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 PVD22461.1 - 6.6 6.6 9.5 15 5.4 8.3 2.4 2 0 0 2 2 1 0 RING-like zinc finger Rad51 PF08423.11 PVD22462.1 - 2e-06 27.3 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 PVD22462.1 - 0.00078 19.1 0.1 0.67 9.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain RabGAP-TBC PF00566.18 PVD22463.1 - 2.6e-51 174.3 0.2 5.5e-51 173.3 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DHC PF09626.10 PVD22463.1 - 0.0039 18.0 1.2 0.017 16.0 1.2 2.1 1 0 0 1 1 1 1 Dihaem cytochrome c Pkinase PF00069.25 PVD22464.1 - 6e-40 137.3 0.0 6.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DNA_pol_A_exo1 PF01612.20 PVD22464.1 - 1.6e-19 70.3 0.0 2.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase_Tyr PF07714.17 PVD22464.1 - 3.9e-13 49.3 0.0 7.7e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PVD22464.1 - 7.5e-05 23.4 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 PVD22464.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 PVD22465.1 - 2.5e-37 128.6 3.6 1.4e-34 119.7 0.8 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Glyco_transf_25 PF01755.17 PVD22465.1 - 5.7e-29 101.4 0.0 1.6e-27 96.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 PVD22465.1 - 4.1e-12 46.4 0.6 1.3e-11 44.8 0.6 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 PVD22465.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.6 1 1 0 1 1 1 1 Anp1 CAP59_mtransfer PF11735.8 PVD22465.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 V-ATPase_G PF03179.15 PVD22466.1 - 5.4e-33 113.7 17.2 6.1e-33 113.5 17.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ApoLp-III PF07464.11 PVD22466.1 - 0.22 11.6 10.6 1.4 9.0 10.3 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 PVD22466.1 - 0.47 9.8 11.8 0.54 9.6 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PCEMA1 PF07418.11 PVD22466.1 - 0.51 9.8 7.5 0.61 9.6 7.5 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Fib_alpha PF08702.10 PVD22466.1 - 0.73 10.0 10.4 1.5 9.0 10.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2827 PF10933.8 PVD22466.1 - 1.1 7.9 4.8 0.4 9.3 2.7 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2827) TROVE PF05731.11 PVD22467.1 - 1e-19 70.9 0.4 5e-16 58.8 0.0 3.0 1 1 1 2 2 2 2 TROVE domain Abhydrolase_6 PF12697.7 PVD22468.1 - 1.8e-09 38.5 0.0 1.1e-05 26.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD22468.1 - 2e-07 30.6 0.0 1.5e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD22468.1 - 1.7e-05 24.6 0.0 0.00065 19.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 PVD22468.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Rhomboid PF01694.22 PVD22469.1 - 2.4e-36 125.0 7.1 2.4e-36 125.0 7.1 1.6 2 0 0 2 2 2 1 Rhomboid family EF-hand_1 PF00036.32 PVD22469.1 - 0.00051 19.4 0.4 0.0012 18.2 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PVD22469.1 - 0.0041 17.5 0.2 0.0078 16.6 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD22469.1 - 0.036 14.0 0.2 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain RasGEF PF00617.19 PVD22474.1 - 7.7e-50 169.5 1.9 1.2e-49 168.9 1.4 1.5 1 1 0 1 1 1 1 RasGEF domain DUF3492 PF11997.8 PVD22474.1 - 0.0093 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) MFS_1 PF07690.16 PVD22475.1 - 1.2e-35 123.1 31.4 1.1e-18 67.3 7.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD22475.1 - 1.4e-09 37.7 26.9 6.5e-08 32.3 7.3 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB YbhQ PF11076.8 PVD22475.1 - 0.036 14.1 0.3 0.036 14.1 0.3 3.5 3 2 1 4 4 4 0 Putative inner membrane protein YbhQ Pam17 PF08566.10 PVD22475.1 - 0.99 9.2 3.8 0.51 10.2 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF4602 PF15375.6 PVD22476.1 - 1e-10 42.0 8.7 2.2e-10 41.0 8.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Acyl_transf_3 PF01757.22 PVD22477.1 - 3.7e-24 85.4 32.5 7.9e-24 84.3 32.5 1.6 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.22 PVD22479.1 - 6.8e-20 71.4 33.5 4.9e-17 62.0 33.5 2.1 1 1 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.22 PVD22481.1 - 2.4e-20 72.9 39.1 3.7e-20 72.3 39.1 1.3 1 0 0 1 1 1 1 Acyltransferase family ITI_HC_C PF06668.12 PVD22481.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Filament PF00038.21 PVD22483.1 - 0.0034 17.0 3.6 0.0034 17.0 3.6 1.8 2 0 0 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.12 PVD22483.1 - 0.0094 16.0 1.5 0.0094 16.0 1.5 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PVD22483.1 - 0.062 13.3 3.7 0.28 11.2 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ald_deCOase PF11266.8 PVD22483.1 - 0.18 11.5 0.6 0.29 10.8 0.4 1.4 2 0 0 2 2 2 0 Long-chain fatty aldehyde decarbonylase DUF16 PF01519.16 PVD22483.1 - 0.48 10.9 12.7 0.061 13.8 6.3 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 PVD22483.1 - 0.63 10.5 4.5 1.7 9.1 1.9 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Mei5_like PF17021.5 PVD22483.1 - 0.66 10.0 4.0 0.41 10.7 1.7 1.8 2 0 0 2 2 2 0 Putative double-strand recombination repair-like DUF1043 PF06295.12 PVD22483.1 - 2.1 8.4 14.6 1.7 8.7 2.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Prominin PF05478.11 PVD22483.1 - 3.5 5.4 5.7 5.2 4.9 5.7 1.2 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 PVD22483.1 - 4.4 7.5 14.3 0.47 10.6 5.7 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 PVD22483.1 - 5.7 7.4 11.8 0.16 12.4 3.8 2.5 2 1 0 2 2 2 0 Snapin/Pallidin TEX13 PF15186.6 PVD22483.1 - 7.5 6.2 9.2 0.46 10.2 3.8 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Methyltransf_25 PF13649.6 PVD22484.1 - 2.6e-16 60.1 0.1 3.9e-11 43.5 0.1 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PVD22484.1 - 3e-12 47.0 0.0 7.4e-10 39.4 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD22484.1 - 8.1e-11 41.9 0.3 2.8e-10 40.2 0.3 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD22484.1 - 1.2e-06 28.5 0.0 0.0007 19.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PVD22484.1 - 3.1e-05 24.6 0.0 0.021 15.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 PVD22484.1 - 0.0002 21.0 0.0 0.84 9.2 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase small domain TPR_21 PF09976.9 PVD22484.1 - 0.049 13.3 0.0 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain RRF PF01765.19 PVD22485.1 - 2.1e-36 125.3 3.4 2.1e-36 125.3 3.4 1.6 1 1 1 2 2 2 1 Ribosome recycling factor MRFAP1 PF15155.6 PVD22485.1 - 0.00063 20.3 0.3 0.002 18.7 0.2 1.8 2 0 0 2 2 2 1 MORF4 family-associated protein1 AAA_32 PF13654.6 PVD22485.1 - 0.019 13.8 5.8 0.023 13.5 2.9 1.9 2 0 0 2 2 2 0 AAA domain HP1451_C PF18472.1 PVD22485.1 - 0.028 14.4 2.2 14 5.8 0.1 3.8 2 1 2 4 4 4 0 HP1451 C-terminal domain NOG1_N PF17835.1 PVD22485.1 - 0.034 14.1 1.3 0.066 13.2 1.3 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Thiamine_BP PF01910.17 PVD22485.1 - 0.076 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Thiamine-binding protein YtxH PF12732.7 PVD22485.1 - 0.16 12.5 4.7 0.44 11.1 2.8 2.3 2 1 0 2 2 2 0 YtxH-like protein DUF3810 PF12725.7 PVD22485.1 - 0.42 9.9 2.5 0.43 9.9 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Aida_N PF08910.10 PVD22485.1 - 1.6 9.2 4.1 2 8.8 2.6 1.8 2 0 0 2 2 2 0 Aida N-terminus DUF2499 PF10693.9 PVD22486.1 - 0.1 12.9 1.3 0.65 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Transmemb_17 PF09799.9 PVD22486.1 - 1.6 9.4 20.8 0.11 13.1 5.2 3.1 2 1 1 3 3 3 0 Predicted membrane protein PIG-Y PF15159.6 PVD22486.1 - 6.5 7.7 0.0 6.5 7.7 0.0 4.6 5 1 0 5 5 5 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y VHL PF01847.16 PVD22487.1 - 8.5e-24 83.3 0.0 1.2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 VHL beta domain VHL_C PF17211.3 PVD22487.1 - 1.3e-12 47.5 0.1 2.3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 VHL box domain UPF0449 PF15136.6 PVD22488.1 - 1.8e-16 60.5 0.3 2.3e-16 60.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DUF1515 PF07439.11 PVD22488.1 - 0.0076 16.3 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) FapA PF03961.13 PVD22488.1 - 0.03 12.9 1.1 0.031 12.9 1.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4509 PF14970.6 PVD22488.1 - 0.038 13.9 0.1 0.044 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Prominin PF05478.11 PVD22488.1 - 0.051 11.5 0.9 0.057 11.4 0.9 1.0 1 0 0 1 1 1 0 Prominin ZapB PF06005.12 PVD22488.1 - 0.07 13.6 4.3 0.1 13.0 4.3 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TRPM_tetra PF16519.5 PVD22488.1 - 0.078 13.1 0.5 0.13 12.4 0.5 1.4 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Phage_TAC_8 PF10666.9 PVD22488.1 - 0.079 13.2 2.2 0.11 12.8 1.4 1.6 1 1 1 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 Spectrin PF00435.21 PVD22488.1 - 0.11 12.9 2.3 0.16 12.5 2.3 1.3 1 0 0 1 1 1 0 Spectrin repeat DUF2802 PF10975.8 PVD22488.1 - 0.12 12.5 1.8 0.3 11.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) GRP PF07172.11 PVD22490.1 - 0.32 11.7 14.2 0.67 10.7 11.1 2.5 3 0 0 3 3 3 0 Glycine rich protein family DUF2464 PF10240.9 PVD22491.1 - 2.7e-63 214.0 0.0 3.5e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 MFS_1 PF07690.16 PVD22492.1 - 8.7e-08 31.5 0.3 1.2e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Hep_59 PF07052.11 PVD22493.1 - 8.8e-30 103.6 5.3 8.8e-30 103.6 5.3 2.6 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Glyco_transf_7N PF13733.6 PVD22494.1 - 5.8e-21 74.5 0.0 1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 7TM_GPCR_Srw PF10324.9 PVD22494.1 - 0.017 14.4 4.4 0.029 13.7 4.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Glyco_transf_7C PF02709.14 PVD22495.1 - 1.1e-14 53.9 0.1 1.5e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 PVD22495.1 - 6.3e-11 42.0 0.1 1e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 LRAT PF04970.13 PVD22496.1 - 6.8e-19 68.4 0.4 1.9e-18 67.0 0.4 1.7 1 0 0 1 1 1 1 Lecithin retinol acyltransferase 7tm_1 PF00001.21 PVD22496.1 - 1.4e-05 24.6 3.4 0.017 14.5 0.3 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD22496.1 - 6.4e-05 22.4 5.8 0.017 14.4 1.3 3.5 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2684 PF10885.8 PVD22496.1 - 0.072 13.2 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) LRAT PF04970.13 PVD22497.1 - 8.6e-32 110.1 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD22497.1 - 0.0026 17.8 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.14 PVD22497.1 - 0.03 14.2 0.1 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 PPPDE putative peptidase domain LRAT PF04970.13 PVD22498.1 - 1.5e-30 106.1 0.0 1.9e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD22498.1 - 0.00068 19.6 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.14 PVD22498.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Phage_spike_2 PF18781.1 PVD22498.1 - 0.038 14.0 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Phage spike trimer 7tm_1 PF00001.21 PVD22499.1 - 1.7e-09 37.4 5.2 1.7e-09 37.4 5.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MHYT PF03707.16 PVD22499.1 - 8.3 6.7 13.3 4.1 7.6 1.0 3.5 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat 7TM_GPCR_Srx PF10328.9 PVD22500.1 - 0.0026 17.4 3.5 0.0034 17.1 3.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Lipocalin_7 PF14651.6 PVD22501.1 - 0.01 15.8 5.1 0.16 11.9 0.5 2.2 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DUF5020 PF16412.5 PVD22501.1 - 0.037 13.9 0.1 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) SH3_5 PF08460.10 PVD22501.1 - 0.53 10.4 4.5 13 6.0 0.1 3.6 2 2 2 4 4 4 0 Bacterial SH3 domain RL11D PF11088.8 PVD22501.1 - 2.2 8.6 13.3 6.1 7.2 0.2 3.7 1 1 2 4 4 4 0 Glycoprotein encoding membrane proteins RL5A and RL6 Lipocalin_7 PF14651.6 PVD22502.1 - 0.1 12.5 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family LRAT PF04970.13 PVD22503.1 - 3.7e-25 88.7 0.1 4.7e-24 85.1 0.1 2.1 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 PVD22503.1 - 0.0021 17.9 0.1 0.0032 17.3 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3482 PF11981.8 PVD22503.1 - 0.073 12.4 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) LRAT PF04970.13 PVD22504.1 - 1.1e-28 100.0 0.4 1.9e-28 99.3 0.4 1.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD22504.1 - 0.00052 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 PVD22505.1 - 4.9e-24 85.0 0.9 7.6e-24 84.4 0.9 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD22505.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.14 PVD22505.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 PPPDE putative peptidase domain SKG6 PF08693.10 PVD22505.1 - 1.8 8.1 7.0 3.2 7.2 7.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M16_C PF05193.21 PVD22506.1 - 7.3e-13 48.9 0.0 1.3e-09 38.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PVD22506.1 - 8.5e-09 35.5 0.0 9.8e-08 32.1 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 PVD22506.1 - 0.25 10.4 5.0 7 5.7 1.3 3.5 3 1 0 3 3 3 0 Peptidase M16C associated Collagen PF01391.18 PVD22507.1 - 1.1e-153 499.1 644.5 9.3e-10 38.1 28.2 20.8 2 1 11 13 13 13 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 PVD22507.1 - 2.2e-68 230.1 0.0 3.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 PVD22507.1 - 0.00086 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 PVD22507.1 - 0.0046 17.1 0.0 0.024 14.8 0.0 2.0 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PAP2 PF01569.21 PVD22508.1 - 0.065 13.0 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily tRNA-synt_1 PF00133.22 PVD22509.1 - 2.7e-182 607.2 0.5 5.8e-130 434.4 0.0 3.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PVD22509.1 - 9.2e-35 119.8 0.0 2.4e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PVD22509.1 - 4e-12 45.6 0.2 1.5e-05 24.0 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PVD22509.1 - 3.8e-09 36.3 7.6 8.7e-09 35.2 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 PVD22509.1 - 5.1e-05 23.5 1.0 5.1e-05 23.5 1.0 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Jag_N PF14804.6 PVD22509.1 - 0.00057 20.2 0.8 0.0014 18.9 0.2 2.0 2 0 0 2 2 2 1 Jag N-terminus tRNA-synt_1e PF01406.19 PVD22509.1 - 0.037 13.4 0.0 0.037 13.4 0.0 3.3 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain PIEZO PF15917.5 PVD22509.1 - 0.46 9.9 3.8 1 8.8 3.8 1.5 1 0 0 1 1 1 0 Piezo UPF0184 PF03670.13 PVD22510.1 - 1.1e-13 51.4 7.7 1.1e-13 51.3 7.3 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) PI3K_P85_iSH2 PF16454.5 PVD22510.1 - 0.0057 16.3 2.3 0.0074 15.9 2.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EzrA PF06160.12 PVD22510.1 - 0.0059 14.9 1.1 0.0069 14.6 1.1 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SlyX PF04102.12 PVD22510.1 - 0.016 15.8 1.1 0.027 15.1 1.1 1.4 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 PVD22510.1 - 0.027 14.5 1.5 0.038 14.1 1.5 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation FTA4 PF13093.6 PVD22510.1 - 0.042 13.7 0.3 0.047 13.6 0.3 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4164 PF13747.6 PVD22510.1 - 0.047 14.0 3.2 0.079 13.2 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4140 PF13600.6 PVD22510.1 - 0.048 14.1 2.6 0.053 14.0 0.6 1.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 PVD22510.1 - 0.055 13.8 4.4 0.12 12.7 4.2 1.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 PVD22510.1 - 0.055 14.0 5.8 0.069 13.7 5.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 PVD22510.1 - 0.066 12.1 2.7 0.081 11.8 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 PVD22510.1 - 0.08 13.2 0.2 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 PVD22510.1 - 0.11 13.2 0.3 0.17 12.6 0.3 1.4 1 1 0 1 1 1 0 Occludin homology domain Prominin PF05478.11 PVD22510.1 - 0.12 10.4 0.3 0.12 10.3 0.3 1.0 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 PVD22510.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 PVD22510.1 - 0.19 11.5 3.7 0.17 11.7 1.6 2.0 1 1 1 2 2 2 0 Septum formation initiator BRE1 PF08647.11 PVD22510.1 - 0.24 11.5 4.0 0.45 10.6 4.0 1.4 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DASH_Dad3 PF08656.10 PVD22510.1 - 0.25 11.5 1.5 0.47 10.6 1.5 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad3 HSCB_C PF07743.13 PVD22510.1 - 0.25 11.8 5.2 0.39 11.2 5.2 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain UPF0242 PF06785.11 PVD22510.1 - 0.38 10.8 3.9 0.43 10.6 3.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 PVD22510.1 - 0.51 10.6 7.7 3 8.2 7.7 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain JIP_LZII PF16471.5 PVD22510.1 - 1.1 9.5 6.0 1.1 9.5 3.4 1.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II XhlA PF10779.9 PVD22510.1 - 5.1 7.4 5.4 4.5 7.6 1.9 2.1 1 1 1 2 2 2 0 Haemolysin XhlA M PF02370.16 PVD22510.1 - 5.5 7.9 6.9 3.8 8.4 0.2 2.9 3 0 0 3 3 2 0 M protein repeat DEAD PF00270.29 PVD22511.1 - 1.1e-37 129.5 0.1 2.1e-37 128.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD22511.1 - 7.9e-28 97.0 0.6 3.9e-25 88.4 0.3 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PVD22511.1 - 7.5e-09 35.8 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PVD22511.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Suppressor_APC PF11414.8 PVD22512.1 - 4.5e-23 81.1 6.0 4.5e-23 81.1 6.0 2.4 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein TMF_DNA_bd PF12329.8 PVD22512.1 - 0.0026 17.7 1.6 0.0026 17.7 1.6 2.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 PVD22512.1 - 0.4 9.5 11.4 0.37 9.6 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 PVD22512.1 - 0.41 9.2 5.3 0.86 8.1 3.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A APC_N_CC PF16689.5 PVD22512.1 - 0.57 10.3 3.8 0.52 10.4 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF16 PF01519.16 PVD22512.1 - 1.4 9.5 6.2 2 9.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cep57_CLD_2 PF14197.6 PVD22512.1 - 2.7 8.2 7.6 0.98 9.6 3.4 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 GIT_CC PF16559.5 PVD22512.1 - 3.6 7.5 8.0 0.17 11.8 0.7 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pneumo_att_G PF05539.11 PVD22512.1 - 5.2 6.6 10.0 9.5 5.7 10.0 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DivIC PF04977.15 PVD22512.1 - 7.8 6.3 8.8 2.5 7.9 0.7 3.2 2 1 1 3 3 3 0 Septum formation initiator FLYWCH PF04500.16 PVD22513.1 - 5.7e-07 29.6 0.1 1.2e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 FLYWCH zinc finger domain DUF2072 PF09845.9 PVD22513.1 - 0.0032 17.7 3.9 0.0032 17.7 3.9 3.7 3 1 0 3 3 3 1 Zn-ribbon containing protein zf-U1 PF06220.12 PVD22513.1 - 0.0095 15.7 1.5 0.0095 15.7 1.5 2.4 3 0 0 3 3 3 1 U1 zinc finger zf-met PF12874.7 PVD22513.1 - 0.018 15.4 1.3 0.018 15.4 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD22513.1 - 0.66 10.3 11.9 0.025 14.9 4.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 PVD22513.1 - 2.4 8.1 7.5 6.2 6.8 0.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) 7tm_1 PF00001.21 PVD22514.1 - 1.8e-25 89.8 27.4 2.6e-25 89.3 27.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD22514.1 - 0.002 17.9 10.2 0.002 17.9 10.2 1.4 1 1 0 1 1 1 1 Olfactory receptor Aldo_ket_red PF00248.21 PVD22515.1 - 1.3e-08 34.4 0.2 1.6e-08 34.1 0.2 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RB_A PF01858.17 PVD22515.1 - 0.041 13.7 2.5 0.043 13.6 0.5 2.0 2 1 1 3 3 3 0 Retinoblastoma-associated protein A domain HGAL PF15666.5 PVD22515.1 - 0.049 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Germinal center-associated lymphoma DUF3251 PF11622.8 PVD22515.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Pkinase PF00069.25 PVD22516.1 - 2.5e-48 164.8 1.4 2.1e-27 96.2 1.8 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22516.1 - 4e-37 127.9 1.3 2.9e-21 75.9 0.9 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD22516.1 - 0.033 13.5 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PhyH PF05721.13 PVD22518.1 - 1.4e-31 110.5 0.0 1.8e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 PVD22518.1 - 0.017 13.9 0.1 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 PVD22518.1 - 0.03 14.7 0.3 0.12 12.8 0.0 2.1 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase RRP36 PF06102.12 PVD22518.1 - 0.21 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PhyH PF05721.13 PVD22519.1 - 1.7e-30 106.9 0.0 3.1e-30 106.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.25 PVD22520.1 - 8.9e-55 185.9 0.0 1.1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22520.1 - 1.8e-24 86.4 0.0 2.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD22520.1 - 3.4e-05 23.0 0.0 4.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD22520.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PVD22520.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Daxx PF03344.15 PVD22521.1 - 0.0015 18.6 0.4 0.0055 16.8 0.4 2.0 1 0 0 1 1 1 1 Daxx N-terminal Rassf1C-interacting domain HPS6 PF15702.5 PVD22522.1 - 0.12 10.4 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein F-protein PF00469.20 PVD22522.1 - 0.71 9.4 3.4 0.42 10.2 1.0 1.7 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef LRAT PF04970.13 PVD22523.1 - 5.5e-32 110.7 0.0 6.8e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 PVD22523.1 - 0.00025 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Cupin_1 PF00190.22 PVD22523.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin TSP_1 PF00090.19 PVD22525.1 - 1.9e-24 85.6 77.7 4e-06 27.0 6.2 6.7 6 0 0 6 6 6 5 Thrombospondin type 1 domain CBM_14 PF01607.24 PVD22525.1 - 2.8e-21 75.4 11.0 2.3e-13 50.1 3.9 5.4 6 1 1 7 7 7 2 Chitin binding Peritrophin-A domain UPF0731 PF14982.6 PVD22525.1 - 0.78 10.0 16.1 0.53 10.5 0.4 4.3 4 0 0 4 4 4 0 UPF0731 family Lectin_C PF00059.21 PVD22526.1 - 0.00063 20.5 0.0 0.00071 20.3 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD22527.1 - 1.1e-21 77.6 0.9 6.7e-17 62.2 0.4 2.3 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD22527.1 - 0.00036 20.2 0.5 0.00075 19.2 0.5 1.5 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like PknG_rubred PF16919.5 PVD22527.1 - 0.026 14.7 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Cytochrom_C552 PF02335.15 PVD22527.1 - 0.027 13.4 0.1 0.035 13.0 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 IF3_N PF05198.16 PVD22527.1 - 0.073 13.3 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain CsgA PF17334.2 PVD22527.1 - 0.22 12.3 0.0 35 5.2 0.0 2.1 2 0 0 2 2 2 0 Minor curli fiber component A DUF4448 PF14610.6 PVD22528.1 - 0.034 13.9 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glyco_transf_92 PF01697.27 PVD22529.1 - 6.6e-16 58.7 0.0 1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 GOLGA2L5 PF15070.6 PVD22531.1 - 9.3e-86 288.8 89.9 7e-46 157.1 35.4 5.0 2 2 2 4 4 4 3 Putative golgin subfamily A member 2-like protein 5 DENN PF02141.21 PVD22531.1 - 9.1e-49 165.9 1.4 2.7e-48 164.4 1.4 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 PVD22531.1 - 1.5e-09 37.7 3.5 3.9e-09 36.4 3.5 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 PVD22531.1 - 1.4e-06 29.0 1.1 3.7e-06 27.6 1.1 1.7 1 0 0 1 1 1 1 uDENN domain ATG16 PF08614.11 PVD22531.1 - 0.0051 17.1 27.7 0.0051 17.1 27.7 8.3 3 1 6 9 9 9 4 Autophagy protein 16 (ATG16) SPA PF08616.10 PVD22531.1 - 0.017 15.1 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis ER PF01133.17 PVD22531.1 - 6.8 6.8 10.4 0.43 10.6 0.3 3.5 3 0 0 3 3 3 0 Enhancer of rudimentary EST1_DNA_bind PF10373.9 PVD22532.1 - 2.1e-36 125.9 1.1 2.1e-36 125.9 1.1 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 PVD22532.1 - 1.2e-22 81.0 2.9 1.3e-22 80.9 0.6 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-AD PF07776.15 PVD22532.1 - 0.01 16.1 0.6 0.04 14.2 0.6 2.2 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) TPR_2 PF07719.17 PVD22532.1 - 0.02 15.0 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22532.1 - 0.061 13.0 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 PVD22532.1 - 0.096 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat VIT PF08487.10 PVD22533.1 - 2.5e-25 88.8 5.4 6.6e-25 87.5 3.8 2.4 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PVD22533.1 - 1.6e-16 60.6 0.0 2.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD22533.1 - 2e-15 57.5 0.0 3.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD22533.1 - 8.4e-09 36.0 0.0 2.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD22533.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Acetyltransf_2 PF00797.17 PVD22534.1 - 5.3e-08 33.0 0.0 7.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Hamartin PF04388.12 PVD22535.1 - 4.3e-137 458.8 0.1 4.3e-137 458.8 0.1 3.3 2 1 1 3 3 3 1 Hamartin protein zf-CCCH_4 PF18044.1 PVD22536.1 - 8.5e-06 25.4 1.7 1.4e-05 24.8 1.7 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 PVD22536.1 - 1.6e-05 24.8 0.7 5.3e-05 23.2 0.7 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 PVD22536.1 - 0.0031 17.4 1.9 0.0052 16.7 1.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD22536.1 - 0.12 12.4 3.0 0.23 11.6 3.0 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 PVD22536.1 - 0.88 10.1 3.9 1.6 9.3 3.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Myb_DNA-binding PF00249.31 PVD22538.1 - 4.9e-38 129.1 18.8 2.7e-13 49.9 0.1 5.1 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD22538.1 - 1.2e-26 92.7 20.2 3.2e-11 43.3 1.6 6.5 2 1 4 6 6 6 4 Myb-like DNA-binding domain SLIDE PF09111.10 PVD22538.1 - 1.9e-05 24.7 11.8 0.24 11.5 0.1 5.1 2 1 2 4 4 4 2 SLIDE Rap1_C PF11626.8 PVD22538.1 - 0.0019 18.2 5.0 0.72 10.0 0.7 4.9 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain E1_4HB PF16191.5 PVD22538.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Trans_reg_C PF00486.28 PVD22538.1 - 0.22 11.6 1.7 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Linker_histone PF00538.19 PVD22539.1 - 5.1e-30 103.6 1.8 1.8e-29 101.9 1.8 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family MHB PF16525.5 PVD22539.1 - 0.019 15.2 0.3 0.077 13.2 0.3 2.1 1 1 0 1 1 1 0 Haemophore, haem-binding zf-C4 PF00105.18 PVD22540.1 - 7.8e-31 106.4 14.3 2.2e-30 104.9 14.3 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD22540.1 - 1.6e-18 67.1 3.7 7.4e-18 64.9 3.7 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor P_C10 PF14974.6 PVD22541.1 - 6.2e-38 129.0 0.1 7.1e-38 128.9 0.1 1.0 1 0 0 1 1 1 1 Protein C10 eIF3g PF12353.8 PVD22542.1 - 5.1e-43 146.4 3.4 8.9e-43 145.7 3.4 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 PVD22542.1 - 5.2e-20 71.0 0.0 1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD22542.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif CDV3 PF15359.6 PVD22542.1 - 0.021 15.3 1.8 0.058 13.9 1.8 1.8 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 RNA_bind PF08675.11 PVD22542.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 PVD22542.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LIM PF00412.22 PVD22543.1 - 1.5e-14 53.9 2.6 1.5e-14 53.9 2.6 1.7 2 0 0 2 2 2 1 LIM domain Homeodomain PF00046.29 PVD22543.1 - 1.4e-07 31.3 0.2 2.3e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Homeodomain Fumerase_C PF05683.12 PVD22544.1 - 0.12 11.7 0.1 5.9 6.1 0.0 2.3 1 1 1 2 2 2 0 Fumarase C-terminus PRK PF00485.18 PVD22545.1 - 7.7e-40 136.7 0.1 9.1e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PVD22545.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-TRAF PF02176.18 PVD22546.1 - 9e-10 39.1 27.3 3.5e-07 30.8 10.4 3.4 3 1 1 4 4 2 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 PVD22546.1 - 0.0016 18.2 11.1 0.0016 18.2 11.1 4.3 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) TRAF_BIRC3_bd PF16673.5 PVD22546.1 - 0.0028 17.4 3.2 0.0083 15.9 1.2 2.5 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 PVD22546.1 - 0.0038 16.2 4.2 0.006 15.5 4.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C3HC4_4 PF15227.6 PVD22546.1 - 0.017 15.3 11.2 0.017 15.3 11.2 3.7 3 1 1 4 4 2 0 zinc finger of C3HC4-type, RING CbeA_antitoxin PF06154.11 PVD22546.1 - 0.028 15.0 0.1 0.07 13.7 0.1 1.6 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A ATG16 PF08614.11 PVD22546.1 - 0.05 13.8 8.9 0.09 13.0 8.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ufd2P_core PF10408.9 PVD22546.1 - 0.053 12.1 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core KASH_CCD PF14662.6 PVD22546.1 - 0.078 12.8 8.4 0.27 11.1 8.0 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 PVD22546.1 - 0.11 12.8 7.7 0.89 9.9 2.8 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arc_PepC PF06819.11 PVD22546.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain LPP PF04728.13 PVD22546.1 - 0.15 12.5 3.3 1.4 9.4 0.2 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper MbeD_MobD PF04899.12 PVD22546.1 - 0.15 12.2 7.8 1.9 8.6 1.3 3.1 2 1 0 2 2 2 0 MbeD/MobD like DUF4407 PF14362.6 PVD22546.1 - 0.22 10.8 3.4 0.083 12.2 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0184 PF03670.13 PVD22546.1 - 0.27 11.7 1.9 0.92 9.9 0.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) zf-RING_6 PF14835.6 PVD22546.1 - 0.28 11.1 9.1 0.16 11.8 5.8 2.4 2 0 0 2 2 1 0 zf-RING of BARD1-type protein DUF1515 PF07439.11 PVD22546.1 - 0.32 11.0 7.2 0.27 11.3 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Mod_r PF07200.13 PVD22546.1 - 0.52 10.4 6.8 0.38 10.8 4.2 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 PVD22546.1 - 0.7 10.2 5.4 34 4.8 5.4 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BST2 PF16716.5 PVD22546.1 - 0.91 10.1 8.0 0.62 10.7 4.5 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Laminin_II PF06009.12 PVD22546.1 - 1.1 9.3 5.3 3.2 7.8 5.2 1.7 1 1 0 1 1 1 0 Laminin Domain II TMF_DNA_bd PF12329.8 PVD22546.1 - 1.3 9.1 7.4 5.4 7.1 3.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Syntaxin_2 PF14523.6 PVD22546.1 - 1.9 8.9 6.5 12 6.3 6.6 2.0 1 1 0 1 1 1 0 Syntaxin-like protein Baculo_PEP_C PF04513.12 PVD22546.1 - 2.1 8.4 7.9 18 5.4 7.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 PVD22546.1 - 2.3 8.4 8.2 4.2 7.5 2.6 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FUSC PF04632.12 PVD22546.1 - 5.5 5.4 10.7 7.8 4.9 10.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 PVD22546.1 - 6.2 7.4 7.7 11 6.6 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 PVD22546.1 - 6.4 7.3 5.7 17 5.9 0.3 2.9 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 PVD22546.1 - 6.6 7.3 7.3 6.9e+02 0.8 7.3 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 PVD22546.1 - 7.8 6.6 12.6 7.1 6.7 3.4 2.5 1 1 1 2 2 2 0 FlxA-like protein MscS_porin PF12795.7 PVD22546.1 - 8.6 5.8 16.4 16 5.0 16.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TRAF_BIRC3_bd PF16673.5 PVD22547.1 - 4.9e-07 29.4 2.9 2.3e-06 27.3 1.0 2.4 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain MAD PF05557.13 PVD22547.1 - 0.00083 17.9 2.9 0.64 8.3 2.7 2.1 2 0 0 2 2 2 2 Mitotic checkpoint protein Laminin_I PF06008.14 PVD22547.1 - 0.0031 17.2 1.5 0.014 15.1 1.0 1.9 2 0 0 2 2 2 1 Laminin Domain I SLIDE PF09111.10 PVD22547.1 - 0.0044 17.0 0.3 0.044 13.8 0.3 2.4 3 0 0 3 3 3 1 SLIDE CEP209_CC5 PF16574.5 PVD22547.1 - 0.01 16.0 1.1 0.01 16.0 1.1 1.5 2 0 0 2 2 2 1 Coiled-coil region of centrosome protein CE290 CLZ PF16526.5 PVD22547.1 - 0.01 16.2 1.6 2.3 8.7 0.0 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 PVD22547.1 - 0.018 15.5 1.4 0.11 12.9 1.1 2.0 1 1 1 2 2 2 0 Fez1 BLOC1_2 PF10046.9 PVD22547.1 - 0.019 15.2 2.3 1 9.7 1.9 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 PVD22547.1 - 0.021 15.5 0.2 0.34 11.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.12 PVD22547.1 - 0.033 14.2 0.4 0.76 9.8 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PVD22547.1 - 0.079 13.0 2.9 2.6 8.1 1.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 PVD22547.1 - 0.15 11.6 5.2 0.096 12.2 2.3 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Uds1 PF15456.6 PVD22547.1 - 0.19 11.9 2.5 7.2 6.8 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation NPV_P10 PF05531.12 PVD22547.1 - 0.27 11.7 1.2 27 5.3 0.4 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 PVD22547.1 - 0.36 11.2 4.5 28 5.2 1.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 PVD22547.1 - 0.49 10.9 4.6 4.7 7.7 3.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB HIP1_clath_bdg PF16515.5 PVD22547.1 - 0.62 10.7 5.4 0.44 11.2 2.4 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 PVD22547.1 - 0.64 10.1 5.9 0.9 9.6 3.6 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 PVD22547.1 - 0.77 9.7 5.9 8 6.5 4.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit CTD PF12815.7 PVD22548.1 - 4.5e-06 27.1 0.9 0.28 11.8 0.9 3.9 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 FtsK_SpoIIIE_N PF12538.8 PVD22548.1 - 0.51 10.6 21.3 11 6.3 3.1 3.3 1 1 2 3 3 3 0 DNA transporter PKD_2 PF16407.5 PVD22548.1 - 1.3 9.2 21.0 7.4 6.7 3.0 3.0 1 1 2 3 3 3 0 PKD-like family RVT_1 PF00078.27 PVD22550.1 - 4.9e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSP_1 PF00090.19 PVD22551.1 - 2.3e-11 43.7 22.8 3.7e-05 23.8 2.0 3.8 3 0 0 3 3 3 3 Thrombospondin type 1 domain CxC3 PF18804.1 PVD22551.1 - 0.094 12.6 3.2 0.13 12.2 1.4 2.0 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Furin-like_2 PF15913.5 PVD22551.1 - 0.7 10.1 8.3 3.6 7.8 1.3 3.3 2 2 0 2 2 2 0 Furin-like repeat, cysteine-rich EF-hand_1 PF00036.32 PVD22552.1 - 1.2e-07 30.8 13.4 0.00097 18.5 0.1 5.0 3 2 2 5 5 5 4 EF hand EF-hand_6 PF13405.6 PVD22552.1 - 4.1e-06 26.3 11.1 0.0011 18.7 0.1 5.1 3 2 2 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 PVD22552.1 - 0.00017 22.0 14.7 0.0021 18.5 1.8 4.7 4 2 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD22552.1 - 5.2 6.7 11.9 44 3.8 0.0 4.7 4 1 1 5 5 5 0 EF hand HtrL_YibB PF09612.10 PVD22553.1 - 1.2e-06 28.3 0.1 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) MuF_C PF18819.1 PVD22553.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain DUF1932 PF09130.11 PVD22553.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) DSBA PF01323.20 PVD22553.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain SP_C-Propep PF08999.10 PVD22555.1 - 0.087 12.6 6.6 0.24 11.2 6.6 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Shisa PF13908.6 PVD22555.1 - 0.15 12.3 5.1 5.4 7.2 1.3 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 PVD22555.1 - 0.61 9.9 4.0 1.5 8.7 4.0 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF3357 PF11837.8 PVD22555.1 - 0.93 10.0 3.9 0.52 10.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) WW PF00397.26 PVD22557.1 - 0.37 10.9 5.2 1.1 9.4 5.2 1.8 1 0 0 1 1 1 0 WW domain TSP_1 PF00090.19 PVD22558.1 - 7e-06 26.2 13.0 1.5e-05 25.1 13.0 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain HCV_NS5a_C PF12941.7 PVD22558.1 - 0.66 9.8 8.7 0.75 9.6 8.7 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region TSP_1 PF00090.19 PVD22559.1 - 1.2e-20 73.4 62.8 3.1e-06 27.3 4.5 5.9 4 1 1 5 5 5 5 Thrombospondin type 1 domain CBM_14 PF01607.24 PVD22559.1 - 3.7e-06 27.0 0.1 3.7e-06 27.0 0.1 4.2 4 1 0 4 4 4 1 Chitin binding Peritrophin-A domain Kelch_3 PF13415.6 PVD22559.1 - 9.2 6.7 7.5 6.7 7.1 2.4 3.1 2 1 0 2 2 2 0 Galactose oxidase, central domain TSP_1 PF00090.19 PVD22561.1 - 1.8e-38 130.5 170.3 1.1e-06 28.8 8.0 12.3 12 0 0 12 12 12 10 Thrombospondin type 1 domain CBM_14 PF01607.24 PVD22561.1 - 2.9e-17 62.5 10.1 3.7e-10 39.8 0.5 7.7 9 1 1 10 10 10 2 Chitin binding Peritrophin-A domain DUF5465 PF17553.2 PVD22561.1 - 2.3e-07 30.5 3.8 94 4.0 0.1 9.1 8 0 0 8 8 8 0 Family of unknown function (DUF5465) Imm72 PF15584.6 PVD22561.1 - 1e-05 25.5 16.7 5.3 7.3 0.0 7.8 9 0 0 9 9 9 3 Immunity protein 72 Peptidase_S28 PF05577.12 PVD22562.1 - 3.7e-60 203.9 0.0 2.2e-59 201.4 0.0 1.8 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 PVD22562.1 - 0.0081 15.5 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD22562.1 - 0.014 15.1 0.2 0.034 13.8 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD22562.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PVD22562.1 - 0.024 15.2 1.6 0.19 12.3 1.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 PVD22562.1 - 0.048 12.3 0.1 0.15 10.7 0.0 1.7 2 0 0 2 2 2 0 PS-10 peptidase S37 Fibrinogen_C PF00147.18 PVD22563.1 - 4.9e-11 42.8 0.0 6.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain VHL_C PF17211.3 PVD22564.1 - 0.0023 17.9 3.6 40 4.3 0.2 5.5 3 1 2 5 5 5 3 VHL box domain Ank_4 PF13637.6 PVD22565.1 - 3.7e-15 56.1 0.4 6.1e-11 42.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD22565.1 - 6.2e-14 52.3 0.0 8.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22565.1 - 2.3e-12 46.9 0.5 6.1e-11 42.3 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD22565.1 - 8e-12 44.3 0.1 6.8e-05 23.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD22565.1 - 9.3e-09 35.4 0.1 0.0029 18.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat CagY_M PF07337.11 PVD22567.1 - 0.0011 18.5 12.9 2.6 7.7 0.2 4.3 1 1 4 5 5 5 5 DC-EC Repeat BssB_TutG PF18512.1 PVD22567.1 - 0.083 12.8 17.7 63 3.5 0.1 6.7 1 1 6 7 7 7 0 Benzylsuccinate synthase beta subunit MALT1_Ig PF18703.1 PVD22567.1 - 0.39 10.7 0.7 25 4.9 0.1 2.4 1 1 1 2 2 2 0 MALT1 Ig-like domain Inh PF02974.14 PVD22567.1 - 0.53 10.4 7.3 13 6.0 0.3 3.1 1 1 1 2 2 2 0 Protease inhibitor Inh Histone PF00125.24 PVD22568.1 - 2.3e-39 134.8 0.2 2.6e-39 134.6 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PVD22568.1 - 0.00095 19.3 0.1 0.0018 18.4 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PVD22568.1 - 0.0012 19.2 0.1 0.0017 18.7 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PVD22568.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RabGAP-TBC PF00566.18 PVD22569.1 - 1e-52 178.9 0.2 1e-52 178.9 0.2 2.5 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Leu_zip PF15294.6 PVD22569.1 - 1.1 8.7 54.9 2.2 7.7 20.9 3.3 1 1 2 3 3 3 0 Leucine zipper Spuma_A9PTase PF03539.14 PVD22569.1 - 2 8.5 5.4 4.7 7.3 0.2 2.6 2 1 0 2 2 2 0 Spumavirus aspartic protease (A9) XTBD PF11952.8 PVD22570.1 - 5.5e-23 80.5 0.2 6.6e-23 80.3 0.2 1.1 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD PK_C PF02887.16 PVD22570.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain G-patch PF01585.23 PVD22571.1 - 3.1e-10 39.8 3.0 5.8e-10 38.9 3.0 1.5 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 PVD22571.1 - 1e-06 28.6 0.1 3.8e-06 26.8 0.1 2.1 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 PVD22571.1 - 0.0017 18.4 0.5 0.0041 17.2 0.5 1.7 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.26 PVD22571.1 - 0.0018 18.9 0.5 1.2 9.9 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif UCH PF00443.29 PVD22572.1 - 7.5e-61 205.9 0.0 9.2e-60 202.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PVD22572.1 - 6.8e-24 84.3 0.4 5e-13 49.5 0.0 3.8 4 1 0 4 4 4 2 DUSP domain UCH_1 PF13423.6 PVD22572.1 - 5e-21 75.6 0.1 9.4e-18 64.9 0.1 3.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PPP1R35_C PF15503.6 PVD22572.1 - 1.9 8.3 4.5 9.8 6.0 0.7 3.1 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TRM PF02005.16 PVD22573.1 - 1.6e-32 113.2 0.0 9.5e-21 74.4 0.0 2.3 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase BTB PF00651.31 PVD22574.1 - 1.7e-21 76.5 0.3 4.6e-20 71.9 0.0 3.0 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 PVD22574.1 - 0.0005 20.1 0.4 0.17 12.0 0.0 2.9 3 0 0 3 3 3 2 BTB And C-terminal Kelch LAT PF15234.6 PVD22575.1 - 0.058 13.1 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells ANAPC4_WD40 PF12894.7 PVD22576.1 - 8.8e-06 25.9 0.0 0.0029 17.9 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 PVD22577.1 - 1.2e-05 26.0 21.8 1.2e-05 26.0 21.8 13.6 3 3 8 11 11 11 3 Nucleoporin FG repeat region EMI PF07546.13 PVD22579.1 - 4.5e-11 43.3 8.1 4.5e-11 43.3 8.1 2.9 1 1 1 2 2 1 1 EMI domain EGF_CA PF07645.15 PVD22579.1 - 6.7e-09 35.8 8.9 6.7e-09 35.8 8.9 3.9 3 1 1 4 4 4 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD22579.1 - 3.1e-07 30.6 8.1 3.1e-07 30.6 8.1 3.4 3 1 1 4 4 3 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 PVD22579.1 - 3.7e-06 27.4 21.6 0.0028 18.2 9.0 3.4 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 PVD22579.1 - 6.2e-05 23.2 25.6 0.019 15.3 11.8 2.8 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.7 PVD22579.1 - 0.00078 19.3 0.7 0.00078 19.3 0.7 3.7 3 2 0 3 3 2 1 Complement Clr-like EGF-like Med4 PF10018.9 PVD22579.1 - 0.0012 18.6 0.1 0.002 17.9 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 EGF_2 PF07974.13 PVD22579.1 - 0.0019 18.5 15.0 0.0019 18.5 15.0 2.7 2 0 0 2 2 2 1 EGF-like domain BRE1 PF08647.11 PVD22579.1 - 0.0048 16.9 0.4 0.0091 16.0 0.4 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase LPP PF04728.13 PVD22579.1 - 0.018 15.4 1.1 0.31 11.4 0.4 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Tecti-min-caps PF09300.10 PVD22579.1 - 0.018 15.1 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Tectiviridae, minor capsid CENP-F_leu_zip PF10473.9 PVD22579.1 - 0.03 14.4 0.7 0.042 13.9 0.1 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EGF_3 PF12947.7 PVD22579.1 - 0.041 14.1 5.2 0.041 14.1 5.2 3.3 2 2 0 2 2 2 0 EGF domain DNA_pol_viral_C PF00336.18 PVD22579.1 - 0.068 12.6 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DHR10 PF18595.1 PVD22579.1 - 0.13 12.3 0.6 0.26 11.4 0.2 1.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain ABC_tran_CTD PF16326.5 PVD22579.1 - 0.16 12.2 0.5 19 5.6 0.5 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Exo_endo_phos_2 PF14529.6 PVD22580.1 - 0.00013 21.8 2.2 0.00066 19.5 0.1 2.5 1 1 0 2 2 2 1 Endonuclease-reverse transcriptase Acetyltransf_15 PF17013.5 PVD22580.1 - 0.016 14.7 0.2 0.22 11.0 0.1 2.1 1 1 1 2 2 2 0 Putative acetyl-transferase I-set PF07679.16 PVD22581.1 - 5.8e-09 35.9 0.1 0.55 10.3 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22581.1 - 4.6e-08 33.5 12.6 0.24 12.0 0.3 5.5 4 1 1 5 5 5 4 Immunoglobulin domain V-set PF07686.17 PVD22581.1 - 9.6e-08 32.2 10.4 1.4 9.1 1.1 5.3 4 1 0 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD22581.1 - 2e-05 24.6 0.3 3.2 7.9 0.0 5.0 4 1 0 4 4 4 2 Izumo-like Immunoglobulin domain ig PF00047.25 PVD22581.1 - 5.1e-05 23.4 6.9 6.6 7.0 0.2 5.6 4 1 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 PVD22581.1 - 0.00057 20.2 17.9 0.43 11.0 1.5 6.0 4 2 1 5 5 5 2 Immunoglobulin domain EGF_3 PF12947.7 PVD22581.1 - 0.34 11.1 2.7 6.1 7.1 0.1 4.0 4 0 0 4 4 4 0 EGF domain PSI PF01437.25 PVD22581.1 - 2.3 8.8 8.6 87 3.8 0.1 4.5 5 0 0 5 5 5 0 Plexin repeat V-set PF07686.17 PVD22582.1 - 3.3e-05 24.0 6.9 0.064 13.4 0.9 3.3 3 0 0 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 PVD22582.1 - 0.00013 21.9 0.2 0.52 10.4 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22582.1 - 0.00014 22.4 4.9 0.21 12.2 0.5 3.3 2 1 0 2 2 2 2 Immunoglobulin domain DUF2075 PF09848.9 PVD22582.1 - 0.0027 17.0 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 PVD22582.1 - 0.0031 17.9 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 PVD22582.1 - 0.0043 17.4 0.0 0.0071 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD22582.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD22582.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 PVD22582.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PVD22582.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 PVD22582.1 - 0.075 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein IstB_IS21 PF01695.17 PVD22582.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 PVD22582.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PVD22582.1 - 0.19 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNase_H PF00075.24 PVD22583.1 - 2.1e-12 47.4 0.0 1.3e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 PVD22583.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 PVD22583.1 - 0.15 12.8 0.6 0.45 11.3 0.3 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase I-set PF07679.16 PVD22585.1 - 9.1e-10 38.5 0.5 0.025 14.6 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain V-set PF07686.17 PVD22585.1 - 8.8e-09 35.5 6.3 0.043 14.0 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22585.1 - 4.6e-08 33.5 12.3 0.053 14.1 1.3 4.7 3 2 0 3 3 3 3 Immunoglobulin domain DUF2034 PF10356.9 PVD22585.1 - 5.1e-05 22.8 0.0 0.067 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Ig_2 PF13895.6 PVD22585.1 - 0.00049 20.4 14.2 0.13 12.6 1.1 4.5 1 1 2 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD22585.1 - 0.0022 18.2 9.0 2.3 8.5 0.3 4.2 3 2 0 3 3 3 2 Immunoglobulin domain PSI PF01437.25 PVD22585.1 - 0.031 14.8 0.0 18 6.0 0.0 2.7 2 0 0 2 2 2 0 Plexin repeat TMEM154 PF15102.6 PVD22585.1 - 0.047 13.6 0.2 0.047 13.6 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD22585.1 - 0.083 13.6 0.9 0.23 12.2 0.1 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal IL6Ra-bind PF09240.10 PVD22585.1 - 0.092 13.2 10.9 0.9 10.0 1.0 4.1 3 2 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding Filamin PF00630.19 PVD22585.1 - 0.18 12.6 1.5 38 5.2 0.1 3.2 3 1 0 3 3 3 0 Filamin/ABP280 repeat Myb_DNA-bind_5 PF13873.6 PVD22586.1 - 1.2e-05 25.3 0.5 2.3e-05 24.4 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PVD22586.1 - 0.01 16.2 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain I-set PF07679.16 PVD22587.1 - 9.3e-09 35.2 0.2 0.13 12.3 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22587.1 - 2e-07 31.5 6.9 0.16 12.6 0.7 4.5 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 PVD22587.1 - 1.1e-06 28.7 3.3 0.29 11.3 0.1 4.1 3 1 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 PVD22587.1 - 7.1e-05 22.9 1.1 4.5 7.5 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain DUF4371 PF14291.6 PVD22587.1 - 0.00083 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Ig_2 PF13895.6 PVD22587.1 - 0.0083 16.4 8.8 2.6 8.5 0.7 4.3 2 1 1 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 PVD22587.1 - 0.084 12.5 3.7 0.71 9.5 0.0 3.4 4 0 0 4 4 4 0 Immunoglobulin domain DUF2034 PF10356.9 PVD22587.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Izumo-Ig PF16706.5 PVD22587.1 - 0.11 12.5 0.0 4.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain I-set PF07679.16 PVD22588.1 - 1.2e-23 82.9 9.0 0.1 12.7 0.0 9.9 10 0 0 10 10 10 7 Immunoglobulin I-set domain V-set PF07686.17 PVD22588.1 - 4.2e-20 72.0 32.2 0.016 15.4 0.1 9.7 9 0 0 9 9 9 7 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22588.1 - 3.7e-16 59.5 45.9 0.25 12.0 0.3 11.5 9 4 1 10 10 10 9 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22588.1 - 2.7e-06 27.3 10.4 0.036 14.1 0.1 8.4 8 3 0 8 8 8 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD22588.1 - 3.7e-06 27.1 23.9 2.3 8.6 0.1 9.2 9 1 0 9 9 9 3 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.6 PVD22588.1 - 5.2e-05 23.5 53.6 0.14 12.5 0.5 12.0 6 5 5 11 11 11 6 Immunoglobulin domain Ig_6 PF18452.1 PVD22588.1 - 0.00087 18.8 17.5 6 6.5 0.0 8.3 9 0 0 9 9 9 2 Immunoglobulin domain bMG1 PF17970.1 PVD22588.1 - 0.011 15.7 0.1 20 5.3 0.0 3.3 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG1 domain ig PF00047.25 PVD22588.1 - 0.034 14.3 39.6 6.4 7.0 0.1 10.9 11 2 1 12 12 12 0 Immunoglobulin domain Auxin_resp PF06507.13 PVD22588.1 - 0.086 13.1 0.0 0.45 10.8 0.0 2.3 1 0 0 1 1 1 0 Auxin response factor I-set PF07679.16 PVD22589.1 - 1.5e-22 79.5 5.1 0.016 15.2 0.0 8.8 8 0 0 8 8 8 6 Immunoglobulin I-set domain V-set PF07686.17 PVD22589.1 - 7.2e-17 61.5 34.8 0.00059 20.0 0.1 9.0 8 2 1 9 9 9 6 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22589.1 - 7.5e-13 48.9 44.4 0.21 12.2 0.3 11.2 9 3 2 11 11 11 5 Immunoglobulin domain Ig_4 PF16680.5 PVD22589.1 - 6.6e-06 26.3 15.3 12 6.3 0.3 8.6 8 0 0 8 8 8 1 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.6 PVD22589.1 - 0.00025 21.3 50.8 0.63 10.4 0.2 11.0 5 5 3 9 9 9 5 Immunoglobulin domain bMG1 PF17970.1 PVD22589.1 - 0.00052 20.0 0.1 12 6.0 0.0 4.1 5 0 0 5 5 5 1 Bacterial Alpha-2-macroglobulin MG1 domain Ig_6 PF18452.1 PVD22589.1 - 0.0033 16.9 12.1 6.1 6.5 0.0 7.1 7 0 0 7 7 7 1 Immunoglobulin domain V-set_2 PF15910.5 PVD22589.1 - 0.012 15.6 0.1 1.6 8.8 0.0 4.1 3 0 0 3 3 3 0 ICOS V-set domain ig PF00047.25 PVD22589.1 - 0.64 10.2 40.2 2.5 8.3 0.1 10.0 9 4 1 10 10 10 0 Immunoglobulin domain V-set PF07686.17 PVD22590.1 - 6.2e-09 36.0 3.1 0.0061 16.7 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22590.1 - 8.5e-09 35.9 1.6 0.037 14.6 0.1 4.4 3 0 0 3 3 3 2 Immunoglobulin domain EphA2_TM PF14575.6 PVD22590.1 - 3.9e-08 34.1 1.0 0.007 17.2 0.4 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Ig_6 PF18452.1 PVD22590.1 - 1.2e-05 24.8 0.8 0.25 11.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain GAPT PF11770.8 PVD22590.1 - 1.5e-05 25.0 3.3 0.0089 15.9 0.2 2.6 2 0 0 2 2 2 2 GRB2-binding adapter (GAPT) I-set PF07679.16 PVD22590.1 - 4.5e-05 23.4 0.2 1.2 9.3 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin I-set domain Gemini_mov PF01708.16 PVD22590.1 - 5.7e-05 22.8 0.6 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 Geminivirus putative movement protein DUF4448 PF14610.6 PVD22590.1 - 5.8e-05 23.0 0.4 0.25 11.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) S1FA PF04689.13 PVD22590.1 - 0.00017 21.6 4.5 0.1 12.7 0.3 2.4 2 0 0 2 2 2 2 DNA binding protein S1FA TMEM154 PF15102.6 PVD22590.1 - 0.0002 21.3 1.9 0.14 12.1 0.1 2.5 2 0 0 2 2 2 2 TMEM154 protein family Ig_2 PF13895.6 PVD22590.1 - 0.00032 21.0 4.6 0.45 10.9 0.4 3.3 2 0 0 2 2 2 2 Immunoglobulin domain Nucleoside_tran PF01733.18 PVD22590.1 - 0.00069 19.1 0.5 0.14 11.5 0.1 2.4 2 0 0 2 2 2 1 Nucleoside transporter DUF4366 PF14283.6 PVD22590.1 - 0.0012 18.9 0.1 2.8 8.0 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4366) PspB PF06667.12 PVD22590.1 - 0.0014 18.7 0.1 0.46 10.6 0.0 2.4 2 0 0 2 2 2 1 Phage shock protein B DUF2627 PF11118.8 PVD22590.1 - 0.0019 18.8 0.1 2.2 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) ECSCR PF15820.5 PVD22590.1 - 0.0025 17.6 0.9 1.5 8.6 0.1 2.7 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator ETRAMP PF09716.10 PVD22590.1 - 0.0028 17.7 0.4 3 8.0 0.0 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Comm PF15957.5 PVD22590.1 - 0.003 17.9 0.5 1 9.7 0.1 2.6 2 0 0 2 2 2 1 Commissureless COX8 PF02285.15 PVD22590.1 - 0.005 16.7 0.7 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DUF2162 PF09930.9 PVD22590.1 - 0.0059 16.0 0.1 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Predicted transporter (DUF2162) MFS_Mycoplasma PF07672.13 PVD22590.1 - 0.0076 15.6 1.4 0.058 12.7 0.4 2.2 2 0 0 2 2 2 1 Mycoplasma MFS transporter Pox_A14 PF05767.12 PVD22590.1 - 0.018 15.2 0.4 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SP_C-Propep PF08999.10 PVD22590.1 - 0.018 14.8 2.5 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF4381 PF14316.6 PVD22590.1 - 0.019 15.2 0.0 0.92 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4330 PF14221.6 PVD22590.1 - 0.021 15.0 1.9 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) DUF5391 PF17369.2 PVD22590.1 - 0.023 14.7 4.4 2.3 8.3 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5391) PAP_PilO PF06864.12 PVD22590.1 - 0.027 13.3 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Vma12 PF11712.8 PVD22590.1 - 0.029 14.4 0.3 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3169 PF11368.8 PVD22590.1 - 0.031 13.8 1.9 0.33 10.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Stevor PF17410.2 PVD22590.1 - 0.033 13.8 7.9 1.2 8.6 0.3 2.6 2 1 1 3 3 3 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srx PF10328.9 PVD22590.1 - 0.036 13.7 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx ig PF00047.25 PVD22590.1 - 0.044 14.0 4.6 8.6 6.6 0.3 4.2 3 2 0 3 3 3 0 Immunoglobulin domain Vpu PF00558.19 PVD22590.1 - 0.045 13.5 5.3 1.7 8.4 0.5 2.4 2 0 0 2 2 2 0 Vpu protein Tetraspanin PF00335.20 PVD22590.1 - 0.049 13.3 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF5385 PF17359.2 PVD22590.1 - 0.053 13.1 6.5 0.4 10.2 0.7 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5385) COX2_TM PF02790.15 PVD22590.1 - 0.054 13.6 0.3 17 5.6 0.0 2.8 3 0 0 3 3 2 0 Cytochrome C oxidase subunit II, transmembrane domain Pex24p PF06398.11 PVD22590.1 - 0.055 12.5 0.3 0.83 8.6 0.2 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin HemX PF04375.14 PVD22590.1 - 0.062 12.6 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tmemb_9 PF05434.11 PVD22590.1 - 0.071 13.0 1.9 2.1 8.2 0.5 2.8 2 0 0 2 2 2 0 TMEM9 SIT PF15330.6 PVD22590.1 - 0.085 13.3 0.2 6.4 7.3 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT SpoIIIAH PF12685.7 PVD22590.1 - 0.088 12.6 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Phage_holin_2_4 PF16082.5 PVD22590.1 - 0.091 12.5 0.9 4 7.2 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like OAD_gamma PF04277.13 PVD22590.1 - 0.095 13.3 0.2 5.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2621 PF11084.8 PVD22590.1 - 0.11 12.5 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) DUF3792 PF12670.7 PVD22590.1 - 0.12 12.5 4.3 1.5 9.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Phospholamban PF04272.14 PVD22590.1 - 0.12 11.8 1.4 6.1 6.4 0.1 2.8 2 0 0 2 2 2 0 Phospholamban DUF2681 PF10883.8 PVD22590.1 - 0.13 12.6 1.2 3.6 8.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Phage_Gp23 PF10669.9 PVD22590.1 - 0.14 12.5 3.2 0.28 11.5 0.7 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3139 PF11337.8 PVD22590.1 - 0.15 12.7 6.2 5.9 7.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) O-antigen_lig PF13425.6 PVD22590.1 - 0.15 10.8 1.6 3.3 6.4 0.3 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DAG1 PF05454.11 PVD22590.1 - 0.18 11.1 0.9 4.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) 7tm_4 PF13853.6 PVD22590.1 - 0.24 11.1 3.9 4.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Olfactory receptor DUF4446 PF14584.6 PVD22590.1 - 0.29 11.1 1.4 5.6 6.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4834 PF16118.5 PVD22590.1 - 0.44 11.5 8.0 0.21 12.6 0.4 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) LAX PF15681.5 PVD22590.1 - 0.52 9.1 3.8 2.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Lymphocyte activation family X RIFIN PF02009.16 PVD22590.1 - 0.64 9.9 4.9 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Rifin Ig_4 PF16680.5 PVD22590.1 - 0.73 10.1 9.6 5 7.4 0.1 3.8 4 0 0 4 4 2 0 T-cell surface glycoprotein CD3 delta chain Insulin_TMD PF17870.1 PVD22590.1 - 1.1 9.4 10.9 3.1 7.9 0.9 2.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4083 PF13314.6 PVD22590.1 - 2.9 7.9 13.6 2.9 7.9 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4083) NVEALA PF14055.6 PVD22590.1 - 6.4 6.8 5.4 15 5.7 0.3 3.0 2 0 0 2 2 2 0 NVEALA protein DUF5325 PF17259.2 PVD22590.1 - 8.3 6.4 8.7 8.9 6.3 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) HtrL_YibB PF09612.10 PVD22591.1 - 1.4e-15 57.6 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) HTH_8 PF02954.19 PVD22591.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MuF_C PF18819.1 PVD22591.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Pex14_N PF04695.13 PVD22592.1 - 0.067 13.8 4.6 0.086 13.5 4.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TSP_1 PF00090.19 PVD22593.1 - 3.3e-20 72.0 60.5 4.4e-05 23.6 3.0 5.6 5 0 0 5 5 5 5 Thrombospondin type 1 domain Furin-like_2 PF15913.5 PVD22593.1 - 0.09 12.9 16.8 12 6.1 0.0 5.5 4 1 1 5 5 5 0 Furin-like repeat, cysteine-rich UPF0060 PF02694.15 PVD22593.1 - 0.19 12.0 1.6 47 4.3 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family Alpha-amylase_C PF02806.18 PVD22593.1 - 0.85 10.1 6.3 12 6.5 0.0 4.2 2 2 2 4 4 4 0 Alpha amylase, C-terminal all-beta domain KH_1 PF00013.29 PVD22594.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 KH domain AAR2 PF05282.11 PVD22594.1 - 0.041 13.3 2.8 0.054 12.9 2.8 1.1 1 0 0 1 1 1 0 AAR2 protein RRN3 PF05327.11 PVD22594.1 - 0.16 10.5 10.9 0.22 10.0 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 PVD22594.1 - 0.2 10.4 4.3 0.23 10.2 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 PVD22594.1 - 0.3 10.5 12.4 0.4 10.1 12.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PVD22594.1 - 0.44 8.7 10.4 0.56 8.3 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 PVD22594.1 - 0.49 8.7 7.4 0.65 8.2 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SpoIIIAH PF12685.7 PVD22594.1 - 1.6 8.5 10.4 2.5 7.9 10.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Trypan_PARP PF05887.11 PVD22594.1 - 2.1 8.3 3.8 4.6 7.2 3.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.10 PVD22594.1 - 3 7.1 9.8 4.1 6.6 9.8 1.1 1 0 0 1 1 1 0 BUD22 BNIP3 PF06553.12 PVD22594.1 - 3 7.5 10.1 5.8 6.5 9.5 1.8 1 1 1 2 2 2 0 BNIP3 SURF2 PF05477.11 PVD22594.1 - 3.6 7.2 9.5 5.1 6.7 9.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 PVD22594.1 - 3.6 5.8 9.0 4.7 5.4 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 PVD22594.1 - 4.1 6.2 12.9 6.7 5.5 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 PVD22594.1 - 6.7 6.6 15.9 9.1 6.2 15.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 PVD22594.1 - 9.4 4.9 8.5 13 4.4 8.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gln-synt_C PF00120.24 PVD22595.1 - 0.00013 21.1 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1188 PF06690.11 PVD22596.1 - 0.093 12.3 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Gln-synt_C PF00120.24 PVD22597.1 - 1.2e-16 60.7 0.0 7.9e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PVD22597.1 - 2.8e-14 52.6 0.0 4.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Ig_3 PF13927.6 PVD22598.1 - 3.5e-76 251.8 5.3 3.9e-15 56.2 0.3 8.1 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 PVD22598.1 - 1.1e-66 220.9 1.0 5.9e-13 48.7 0.0 8.1 8 0 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.21 PVD22598.1 - 2.2e-52 175.4 17.7 1.6e-10 41.1 1.3 6.5 6 0 0 6 6 6 5 Fibronectin type III domain Ig_2 PF13895.6 PVD22598.1 - 4e-46 155.2 14.6 3.4e-08 33.7 0.2 8.0 8 0 0 8 8 7 6 Immunoglobulin domain ig PF00047.25 PVD22598.1 - 2e-43 146.4 17.5 2.5e-09 37.2 0.4 8.7 8 0 0 8 8 8 7 Immunoglobulin domain V-set PF07686.17 PVD22598.1 - 2.3e-14 53.5 26.8 0.016 15.4 0.5 12.5 10 4 2 12 12 12 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD22598.1 - 2.4e-14 53.1 3.2 0.37 10.9 0.0 7.0 6 0 0 6 6 6 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD22598.1 - 3e-08 33.9 0.0 1.6 9.2 0.0 6.0 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD22598.1 - 3.2e-07 29.8 0.0 0.093 12.3 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22598.1 - 1.4e-06 28.3 0.1 0.013 15.6 0.0 4.5 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD22598.1 - 0.0007 20.1 13.5 0.52 10.9 0.3 6.4 6 1 0 6 6 5 1 Purple acid Phosphatase, N-terminal domain Shisa PF13908.6 PVD22598.1 - 0.0057 16.9 0.8 0.016 15.4 0.8 1.8 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR1 PF02440.15 PVD22598.1 - 0.013 15.3 6.2 0.5 10.2 0.0 4.8 5 0 0 5 5 5 0 Adenovirus E3 region protein CR1 Pkinase_Tyr PF07714.17 PVD22600.1 - 2.2e-35 122.2 0.0 3.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD22600.1 - 2.4e-14 53.3 0.0 1.6e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain V-set PF07686.17 PVD22600.1 - 1.5e-05 25.1 0.1 3.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22600.1 - 2.2e-05 24.9 0.2 6.6e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD22600.1 - 4.2e-05 23.5 0.0 0.00067 19.7 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD22600.1 - 0.00011 22.3 0.5 0.0017 18.5 0.5 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD22600.1 - 0.015 15.6 0.4 0.53 10.7 0.4 2.7 1 1 0 1 1 1 0 Immunoglobulin domain gag-asp_proteas PF13975.6 PVD22602.1 - 0.00052 20.5 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PNMA PF14893.6 PVD22602.1 - 0.0051 16.3 0.0 0.009 15.4 0.0 1.4 1 1 0 1 1 1 1 PNMA Asp_protease_2 PF13650.6 PVD22602.1 - 0.012 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 PVD22602.1 - 0.042 13.9 2.5 0.042 13.9 2.5 2.3 3 0 0 3 3 3 0 Zinc knuckle RVP PF00077.20 PVD22602.1 - 0.096 13.0 0.1 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 PVD22603.1 - 0.00044 19.8 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.16 PVD22605.1 - 3.7e-12 46.1 0.0 0.041 14.0 0.0 4.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22605.1 - 6.9e-10 39.4 12.5 0.17 12.5 1.5 5.6 5 2 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 PVD22605.1 - 1.9e-08 34.4 4.1 0.091 12.9 0.1 4.9 4 2 0 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD22605.1 - 5.1e-07 29.9 12.1 0.15 12.4 1.6 5.5 3 1 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD22605.1 - 5.7e-06 26.4 5.6 7.2 6.9 0.0 5.2 4 1 0 4 4 4 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22605.1 - 0.00034 20.6 0.0 0.63 10.1 0.0 4.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD22605.1 - 0.0011 18.4 2.2 5.9 6.5 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin domain TMEM154 PF15102.6 PVD22605.1 - 0.0079 16.1 0.4 0.0079 16.1 0.4 1.7 2 0 0 2 2 2 1 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD22605.1 - 0.063 14.0 3.5 0.066 14.0 0.3 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal T2SSL PF05134.13 PVD22605.1 - 0.18 11.2 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein L RVT_1 PF00078.27 PVD22606.1 - 6.5e-21 74.9 0.1 9.9e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med1 PF10744.9 PVD22606.1 - 0.074 12.1 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Taxilin PF09728.9 PVD22606.1 - 0.33 10.1 9.1 0.46 9.6 9.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein NtCtMGAM_N PF16863.5 PVD22607.1 - 0.00011 22.4 4.2 0.091 13.0 4.2 3.0 1 1 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PCEMA1 PF07418.11 PVD22607.1 - 6.7 6.2 7.3 1.2 8.6 1.4 2.1 1 1 1 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 V-set PF07686.17 PVD22608.1 - 2.8e-07 30.7 8.9 0.029 14.5 0.7 3.9 3 1 1 4 4 4 3 Immunoglobulin V-set domain I-set PF07679.16 PVD22608.1 - 5.4e-07 29.6 0.3 0.33 11.1 0.0 3.6 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22608.1 - 7.9e-07 29.6 9.8 0.12 13.0 1.4 4.4 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD22608.1 - 0.00064 20.0 15.1 1 9.7 1.2 4.6 2 1 2 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD22608.1 - 0.004 17.3 4.7 9.3 6.5 0.2 4.6 4 2 0 4 4 4 1 Immunoglobulin domain Cadherin_C_2 PF16492.5 PVD22608.1 - 0.028 15.2 0.8 0.076 13.8 0.1 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 PVD22608.1 - 0.12 12.3 1.2 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family ECSCR PF15820.5 PVD22608.1 - 0.44 10.4 3.3 0.9 9.4 1.8 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator IL6Ra-bind PF09240.10 PVD22608.1 - 3 8.3 10.2 2 8.9 1.0 3.9 2 2 1 3 3 3 0 Interleukin-6 receptor alpha chain, binding TMPIT PF07851.13 PVD22609.1 - 2 7.6 10.3 2.7 7.2 10.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein NPR3 PF03666.13 PVD22609.1 - 2 7.1 14.6 2.4 6.8 14.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PspB PF06667.12 PVD22609.1 - 2.2 8.4 5.2 3.7 7.7 1.9 2.6 2 1 1 3 3 3 0 Phage shock protein B Cellulose_synt PF03552.14 PVD22609.1 - 2.3 6.6 7.7 2.6 6.4 7.7 1.0 1 0 0 1 1 1 0 Cellulose synthase LtuB PF17455.2 PVD22609.1 - 3.2 8.4 9.7 0.38 11.4 0.8 2.2 1 1 1 2 2 2 0 Late transcription unit B Exonuc_VII_L PF02601.15 PVD22609.1 - 5.9 6.4 11.4 6.4 6.3 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 PVD22609.1 - 7.9 5.0 13.6 9.5 4.7 13.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A I-set PF07679.16 PVD22611.1 - 5.7e-10 39.1 0.4 0.0039 17.2 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22611.1 - 1.8e-08 34.8 12.3 0.02 15.5 0.0 5.4 4 2 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD22611.1 - 4.8e-05 23.5 10.0 2.6 8.3 0.1 5.1 4 3 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 PVD22611.1 - 5.5e-05 23.3 7.2 0.27 11.5 0.0 5.1 4 1 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD22611.1 - 0.00024 21.4 16.4 1.2 9.6 1.4 5.6 2 2 2 4 4 4 3 Immunoglobulin domain Ig_6 PF18452.1 PVD22611.1 - 0.0028 17.2 4.0 0.91 9.1 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22611.1 - 0.01 15.9 3.1 0.19 11.8 0.2 4.0 3 2 1 4 4 4 0 Izumo-like Immunoglobulin domain TMEM154 PF15102.6 PVD22611.1 - 0.046 13.6 0.2 0.046 13.6 0.2 1.7 2 0 0 2 2 2 0 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD22611.1 - 0.14 13.0 3.2 0.18 12.6 0.2 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal FN3_7 PF18447.1 PVD22611.1 - 2 8.8 6.9 30 5.0 0.0 4.0 3 1 1 4 4 4 0 Fibronectin type III domain I-set PF07679.16 PVD22614.1 - 3.7e-15 55.8 0.1 0.0041 17.2 0.0 4.6 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22614.1 - 3.2e-11 43.6 16.1 0.013 16.1 0.1 5.6 5 2 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 PVD22614.1 - 6.1e-08 32.9 17.3 0.016 15.5 1.1 5.6 3 2 1 4 4 4 4 Immunoglobulin domain V-set PF07686.17 PVD22614.1 - 9.7e-08 32.2 8.7 0.062 13.5 0.1 5.0 4 2 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 PVD22614.1 - 4.8e-06 26.6 11.2 0.27 11.5 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22614.1 - 0.00013 21.9 1.9 0.2 11.7 0.2 4.5 4 1 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD22614.1 - 0.00041 19.9 3.1 1 9.0 0.0 4.4 4 0 0 4 4 4 1 Immunoglobulin domain PSI PF01437.25 PVD22614.1 - 0.1 13.2 2.8 31 5.2 0.0 3.6 3 0 0 3 3 3 0 Plexin repeat TIG_plexin PF17960.1 PVD22614.1 - 0.24 11.4 12.0 2.4 8.2 0.5 5.1 4 2 1 5 5 5 0 TIG domain FN3_7 PF18447.1 PVD22614.1 - 0.5 10.7 2.6 1.3e+02 3.0 0.0 3.9 3 0 0 3 3 3 0 Fibronectin type III domain RNase_T PF00929.24 PVD22616.1 - 4.3e-06 27.4 0.0 7.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ig_3 PF13927.6 PVD22616.1 - 0.00014 22.4 2.1 0.65 10.6 0.1 3.2 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD22616.1 - 0.0021 18.4 2.4 0.66 10.4 0.7 2.8 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD22616.1 - 0.0076 16.4 0.8 0.75 10.0 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD22616.1 - 0.0094 16.2 0.2 3.3 8.1 0.1 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 PVD22616.1 - 0.012 15.6 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD22617.1 - 5.8e-05 23.3 4.6 0.36 11.2 0.1 3.6 1 1 2 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 PVD22617.1 - 0.00013 22.5 1.4 0.65 10.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD22617.1 - 0.00027 21.1 0.1 0.052 13.7 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD22617.1 - 0.008 15.7 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Insulin_TMD PF17870.1 PVD22617.1 - 0.33 11.1 4.5 0.7 10.0 4.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2367 PF10164.9 PVD22617.1 - 0.61 10.6 3.7 1.1 9.8 1.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) RVT_1 PF00078.27 PVD22618.1 - 9e-08 31.9 0.1 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD22620.1 - 1.1e-14 54.5 0.1 1.5e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD22621.1 - 4.8e-13 49.1 0.0 9.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APOBEC2 PF18772.1 PVD22622.1 - 0.21 11.7 0.1 4.3 7.3 0.0 2.2 2 0 0 2 2 2 0 APOBEC2 I-set PF07679.16 PVD22624.1 - 2.1e-11 43.7 0.5 0.12 12.4 0.0 4.5 3 1 1 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD22624.1 - 6.6e-11 42.7 11.4 0.027 15.1 1.7 5.1 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 PVD22624.1 - 2.8e-08 33.9 8.8 0.23 11.6 0.6 4.8 3 1 1 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 PVD22624.1 - 5.2e-06 26.6 7.4 3.7 7.8 0.0 4.8 4 2 0 4 4 4 3 Immunoglobulin domain Ig_6 PF18452.1 PVD22624.1 - 0.00027 20.4 2.1 1.9 8.1 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD22624.1 - 0.00049 20.4 14.5 1.1 9.7 2.0 5.3 2 1 2 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD22624.1 - 0.014 15.4 2.0 0.64 10.1 0.0 3.9 3 2 1 4 4 4 0 Izumo-like Immunoglobulin domain DUF2034 PF10356.9 PVD22624.1 - 0.028 13.9 0.0 0.067 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) TMEM154 PF15102.6 PVD22624.1 - 0.15 11.9 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family IL6Ra-bind PF09240.10 PVD22624.1 - 8.2 6.9 11.6 1.8 9.0 1.0 4.1 2 2 1 3 3 3 0 Interleukin-6 receptor alpha chain, binding AAA_19 PF13245.6 PVD22625.1 - 0.0006 20.2 0.1 0.0015 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD22625.1 - 0.0038 17.6 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 PVD22625.1 - 0.0053 16.5 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD22625.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 PVD22625.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 PVD22625.1 - 0.036 13.9 0.4 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PVD22625.1 - 0.037 14.0 0.0 0.088 12.7 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA PF00004.29 PVD22625.1 - 0.042 14.3 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PVD22625.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD22625.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD22625.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 PVD22625.1 - 0.2 10.6 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MgtE_N PF03448.17 PVD22627.1 - 0.1 13.2 1.3 0.54 10.9 0.4 2.5 2 1 0 2 2 2 0 MgtE intracellular N domain I-set PF07679.16 PVD22628.1 - 2.5e-08 33.9 0.2 0.2 11.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 PVD22628.1 - 4.3e-07 30.1 9.9 0.038 14.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD22628.1 - 1.3e-06 28.9 10.8 0.26 11.9 0.5 4.3 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD22628.1 - 0.0028 17.8 6.5 0.71 10.1 0.1 4.0 3 2 0 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 PVD22628.1 - 0.007 15.9 1.7 0.36 10.4 0.1 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD22628.1 - 0.058 13.7 17.6 0.2 12.0 0.7 5.2 2 2 1 3 3 3 0 Immunoglobulin domain TMEM154 PF15102.6 PVD22628.1 - 0.07 13.0 0.2 0.07 13.0 0.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family DAG1 PF05454.11 PVD22628.1 - 0.15 11.4 3.2 0.26 10.6 3.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5385 PF17359.2 PVD22628.1 - 0.29 10.7 0.4 0.47 10.0 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Cadherin_C_2 PF16492.5 PVD22628.1 - 2.2 9.1 10.3 0.42 11.4 0.2 3.4 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal DUF4551 PF15087.6 PVD22629.1 - 0.12 11.1 11.8 0.16 10.8 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 PVD22629.1 - 1.5 8.6 22.6 2.1 8.2 22.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 PVD22629.1 - 2 7.0 8.4 2.1 7.0 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 PVD22629.1 - 2.5 6.4 5.5 3.5 5.9 5.5 1.3 1 0 0 1 1 1 0 Menin MRP-S26 PF14943.6 PVD22629.1 - 3.2 7.6 27.0 6.1 6.7 27.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 GREB1 PF15782.5 PVD22629.1 - 5.6 3.9 8.7 6.6 3.7 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer APH PF01636.23 PVD22630.1 - 2.4e-09 37.5 0.3 3.6e-09 36.9 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SPP PF06550.11 PVD22630.1 - 0.016 14.7 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease Kdo PF06293.14 PVD22630.1 - 0.061 12.7 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF615 PF04751.14 PVD22631.1 - 0.023 14.7 0.3 0.067 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF615) SMC_N PF02463.19 PVD22634.1 - 3.3e-36 124.8 3.8 6.2e-36 123.9 3.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PVD22634.1 - 8.6e-15 55.8 19.3 2.8e-12 47.6 19.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 PVD22634.1 - 6.6e-08 32.7 14.4 3.5e-07 30.3 14.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PVD22634.1 - 7.7e-07 29.2 1.0 2.1e-06 27.8 0.3 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD22634.1 - 2.8e-05 23.8 0.0 6.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HOASN PF14515.6 PVD22634.1 - 0.014 15.8 2.4 3.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices CC2-LZ PF16516.5 PVD22634.1 - 0.8 10.1 20.4 0.43 11.0 2.5 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Pup PF05639.11 PVD22634.1 - 0.99 10.4 3.9 3.7 8.5 0.3 2.7 2 0 0 2 2 2 0 Pup-like protein ABC_tran PF00005.27 PVD22634.1 - 1.5 9.3 6.8 7.1 7.1 6.8 2.5 1 1 0 1 1 1 0 ABC transporter FliS PF02561.14 PVD22634.1 - 3.8 7.8 10.2 2.6 8.4 5.5 2.8 2 1 0 2 2 2 0 Flagellar protein FliS SLATT_5 PF18160.1 PVD22634.1 - 5.8 6.2 6.6 1.2 8.4 0.3 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RVT_1 PF00078.27 PVD22635.1 - 1.1e-15 57.7 0.1 5.6e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yos9_DD PF17880.1 PVD22635.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.7 2 1 0 2 2 2 0 Yos9 dimerzation domain SMC_N PF02463.19 PVD22636.1 - 3.5e-26 92.0 13.2 1.4e-25 90.0 13.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PVD22636.1 - 1.7e-21 76.7 0.1 6.8e-21 74.7 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PVD22636.1 - 7.1e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 PVD22636.1 - 0.011 16.3 11.9 0.17 12.4 7.4 3.9 1 1 0 2 2 2 0 ABC transporter TEX12 PF15219.6 PVD22636.1 - 0.37 11.1 5.6 0.49 10.8 0.2 3.8 3 1 1 4 4 4 0 Testis-expressed 12 CorA PF01544.18 PVD22636.1 - 9.1 5.5 22.9 14 4.9 5.0 3.3 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein ScdA_N PF04405.14 PVD22637.1 - 0.18 11.5 0.5 55 3.5 0.0 2.8 1 1 2 3 3 3 0 Domain of Unknown function (DUF542) CTD PF12815.7 PVD22638.1 - 2.3e-11 44.1 21.0 2e+02 2.6 21.1 4.7 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Hph PF13694.6 PVD22638.1 - 0.054 13.8 31.7 2.8 8.2 1.5 4.2 1 1 3 4 4 4 0 Sec63/Sec62 complex-interacting family DinB_2 PF12867.7 PVD22640.1 - 0.00023 21.7 0.1 0.00041 20.8 0.0 1.4 1 1 0 1 1 1 1 DinB superfamily DUF1515 PF07439.11 PVD22640.1 - 0.25 11.4 0.7 0.42 10.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FGE-sulfatase PF03781.16 PVD22641.1 - 2.9e-34 118.8 2.4 4.6e-33 114.9 2.4 2.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 PVD22641.1 - 5.5e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD22641.1 - 0.018 15.6 0.0 0.059 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Med7 PF05983.11 PVD22641.1 - 0.098 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 MED7 protein Methyltransf_12 PF08242.12 PVD22641.1 - 0.17 12.7 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Yip1 PF04893.17 PVD22642.1 - 4.5e-18 65.6 21.6 4.5e-18 65.6 21.6 1.5 1 1 0 1 1 1 1 Yip1 domain DUF4131 PF13567.6 PVD22642.1 - 0.012 15.2 1.3 0.012 15.2 1.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Tim29 PF10171.9 PVD22643.1 - 3e-55 186.3 0.1 3.5e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 RRM_5 PF13893.6 PVD22644.1 - 2e-47 159.9 1.7 4.9e-34 116.6 0.0 4.2 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PVD22644.1 - 6.5e-35 118.8 5.0 2.7e-09 36.7 0.1 4.8 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PVD22644.1 - 1.5e-16 60.3 0.1 2.3e-14 53.4 0.0 3.0 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 PVD22644.1 - 4.8e-08 32.7 0.1 0.51 10.2 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RL PF17797.1 PVD22644.1 - 0.0022 17.9 1.8 0.49 10.4 0.0 3.4 3 1 0 3 3 3 1 RL domain Limkain-b1 PF11608.8 PVD22644.1 - 0.047 13.8 0.0 8.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 Cyto_heme_lyase PF01265.17 PVD22649.1 - 8.1e-70 235.7 13.5 1.5e-68 231.5 13.5 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase E_Pc_C PF06752.12 PVD22649.1 - 0.031 14.4 1.0 0.045 13.9 1.0 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Exo_endo_phos PF03372.23 PVD22650.1 - 0.052 13.0 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Phosphodiest PF01663.22 PVD22651.1 - 1.6e-14 54.3 0.3 6.3e-09 35.9 0.0 2.4 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 PVD22651.1 - 0.003 17.0 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Kri1_C PF12936.7 PVD22652.1 - 2.6e-27 94.8 0.2 2.6e-27 94.8 0.2 5.0 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 PVD22652.1 - 6.5e-21 74.8 18.8 6.5e-21 74.8 18.8 6.8 4 3 2 6 6 6 1 KRI1-like family Kelch_1 PF01344.25 PVD22653.1 - 1.2e-59 197.7 16.6 1.5e-15 56.5 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PVD22653.1 - 5.4e-36 121.7 12.3 6e-10 39.0 0.1 6.4 2 2 4 6 6 6 4 Kelch motif BTB PF00651.31 PVD22653.1 - 1.6e-34 118.4 1.1 1.8e-33 115.1 0.3 2.3 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD22653.1 - 3.2e-27 94.6 0.6 3.2e-27 94.6 0.6 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 PVD22653.1 - 9.1e-22 76.1 8.0 6.4e-05 22.8 0.1 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD22653.1 - 2.4e-18 65.9 0.2 0.00099 19.1 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD22653.1 - 4.3e-12 46.0 10.9 0.00047 20.4 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD22653.1 - 1.5e-10 40.8 6.0 0.051 13.6 0.0 5.3 5 0 0 5 5 5 4 Kelch motif TGF_beta PF00019.20 PVD22654.1 - 1.2e-17 64.8 1.5 1.2e-17 64.8 1.5 2.3 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD22654.1 - 8e-07 29.1 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 TGF-beta propeptide MT PF12777.7 PVD22655.1 - 0.00038 19.6 1.1 0.00038 19.6 1.1 2.9 1 1 3 4 4 4 1 Microtubule-binding stalk of dynein motor FAM91_N PF14647.6 PVD22656.1 - 1.9e-140 467.5 2.2 2.5e-140 467.2 2.2 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 PVD22656.1 - 3.3e-138 461.2 0.0 2.7e-103 346.1 0.0 2.2 1 1 1 2 2 2 2 FAM91 C-terminus RrnaAD PF00398.20 PVD22657.1 - 3.5e-57 193.5 0.0 4.4e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PVD22657.1 - 2.3e-09 37.8 0.0 4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD22657.1 - 2.5e-07 31.2 0.0 4.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD22657.1 - 1.4e-05 25.0 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PVD22657.1 - 0.00032 21.4 0.0 0.0006 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD22657.1 - 0.00049 20.0 0.0 0.00085 19.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 PVD22657.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 PVD22657.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PVD22657.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 PVD22657.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PVD22657.1 - 0.023 14.4 0.1 0.044 13.5 0.1 1.3 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 PVD22657.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 PVD22657.1 - 0.044 13.1 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain tRNA_U5-meth_tr PF05958.11 PVD22657.1 - 0.049 12.6 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.20 PVD22657.1 - 0.054 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 PVD22657.1 - 0.078 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.12 PVD22657.1 - 0.08 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 PVD22657.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DOT1 PF08123.13 PVD22657.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF3480 PF11979.8 PVD22658.1 - 3.3e-164 546.0 0.0 4e-164 545.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) SARA PF11409.8 PVD22658.1 - 8.1e-16 57.9 9.0 8.1e-16 57.9 9.0 2.4 2 0 0 2 2 2 1 Smad anchor for receptor activation (SARA) RNase_T PF00929.24 PVD22660.1 - 1.2e-33 117.0 0.0 1.5e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Branch PF02485.21 PVD22662.1 - 1.6e-38 132.6 0.0 2.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SNF2_N PF00176.23 PVD22663.1 - 6.5e-49 166.5 0.0 1.3e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD22663.1 - 7.9e-05 23.0 0.0 0.00037 20.8 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 PVD22663.1 - 0.00026 21.0 0.5 0.0018 18.3 0.0 2.7 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal HDA2-3 PF11496.8 PVD22663.1 - 0.018 14.2 1.0 0.24 10.5 0.0 3.2 4 0 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 zf-C3HC4_2 PF13923.6 PVD22664.1 - 5.2e-08 32.6 9.0 1.7e-07 31.0 9.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD22664.1 - 2.7e-07 30.3 5.5 7.1e-07 29.0 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22664.1 - 3.3e-07 30.5 8.9 1.3e-06 28.6 8.9 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD22664.1 - 1.1e-06 28.4 8.6 1.1e-06 28.4 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD22664.1 - 0.00013 21.7 7.6 0.00013 21.7 7.6 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD22664.1 - 0.00068 19.6 4.0 0.0011 19.0 2.4 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD22664.1 - 0.0019 18.1 9.0 0.0019 18.1 9.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD22664.1 - 0.0041 17.4 9.3 0.033 14.5 9.3 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PVD22664.1 - 0.0043 17.1 0.9 0.011 15.7 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 PVD22664.1 - 0.034 14.3 4.8 0.18 12.0 4.8 2.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 PVD22664.1 - 0.69 10.1 9.4 1.9 8.7 9.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PVD22664.1 - 0.73 9.7 7.3 1.8 8.4 7.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PVD22664.1 - 0.75 9.5 6.0 1.9 8.2 6.0 1.7 1 0 0 1 1 1 0 P-11 zinc finger Baculo_IE-1 PF05290.11 PVD22664.1 - 1.6 8.7 6.0 3.3 7.6 6.0 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Adap_comp_sub PF00928.21 PVD22665.1 - 2.7e-92 308.9 0.8 3.6e-92 308.5 0.2 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PVD22665.1 - 1.7e-09 37.8 3.0 2.9e-09 37.0 3.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 PVD22665.1 - 0.091 12.8 0.2 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain muHD PF10291.9 PVD22665.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF1359 PF07097.11 PVD22665.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) DUF5088 PF17008.5 PVD22666.1 - 0.039 13.7 2.2 11 5.7 0.1 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF5088) NMT1_3 PF16868.5 PVD22666.1 - 1.1 8.7 13.1 15 4.9 0.2 4.2 1 1 5 6 6 6 0 NMT1-like family DUF3194 PF11419.8 PVD22666.1 - 1.3 9.4 6.4 35 4.9 0.3 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF3194) PDZ PF00595.24 PVD22669.1 - 1.7e-07 31.5 0.1 2.9e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain TPR_16 PF13432.6 PVD22671.1 - 0.00016 22.2 1.0 0.0029 18.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD22671.1 - 0.00097 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD22671.1 - 0.0031 18.2 0.1 0.14 13.0 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22671.1 - 0.0046 17.4 0.0 7.7 7.1 0.0 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22671.1 - 0.0053 16.4 0.2 0.013 15.2 0.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 PVD22671.1 - 0.0065 16.6 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD22671.1 - 0.0067 16.5 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD22671.1 - 0.011 15.9 0.1 0.028 14.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD22671.1 - 0.022 15.0 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22671.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD22671.1 - 0.17 12.3 0.0 0.71 10.4 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.6 PVD22672.1 - 2.6e-09 36.9 0.3 8.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase LRR_8 PF13855.6 PVD22673.1 - 2e-14 53.1 14.2 4.1e-11 42.5 5.2 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD22673.1 - 1e-12 48.1 12.2 5.4e-07 29.8 1.1 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD22673.1 - 2.1e-05 24.5 7.5 3.4 8.6 0.7 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat DUF4571 PF15137.6 PVD22673.1 - 0.069 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) LRR_6 PF13516.6 PVD22673.1 - 0.6 10.3 0.2 0.6 10.3 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 PVD22674.1 - 0.076 12.8 1.0 0.44 10.3 0.7 2.0 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 PVD22674.1 - 0.079 13.4 0.6 0.15 12.5 0.3 1.6 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) FERM_C PF09380.10 PVD22676.1 - 4.6e-19 68.6 0.0 8.5e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD22676.1 - 4.7e-14 52.8 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PVD22676.1 - 8e-12 44.9 0.1 1.5e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 PVD22676.1 - 3.1e-11 43.2 0.6 9.1e-11 41.7 0.6 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) Cys_Met_Meta_PP PF01053.20 PVD22678.1 - 9.1e-138 458.9 0.0 1.4e-137 458.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Kinesin PF00225.23 PVD22678.1 - 1.3e-94 316.9 0.3 2.5e-94 315.9 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD22678.1 - 4.9e-15 55.8 0.8 2.4e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Aminotran_1_2 PF00155.21 PVD22678.1 - 2.7e-08 33.4 0.8 5.1e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PVD22678.1 - 0.011 14.7 0.1 0.026 13.5 0.1 1.6 1 0 0 1 1 1 0 Aminotransferase class-V CABIT PF12736.7 PVD22679.1 - 5.9e-11 42.2 0.0 8.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, DUF3106 PF11304.8 PVD22681.1 - 3.3e-07 30.7 0.0 0.026 15.0 0.0 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3106) WAC_Acf1_DNA_bd PF10537.9 PVD22681.1 - 2.5e-06 28.0 3.1 34 5.0 0.0 6.2 1 1 7 8 8 8 1 ATP-utilising chromatin assembly and remodelling N-terminal YjgF_endoribonc PF14588.6 PVD22681.1 - 0.007 16.5 0.1 25 5.0 0.0 3.8 1 1 3 4 4 4 1 YjgF/chorismate_mutase-like, putative endoribonuclease TMEM131_like PF12371.8 PVD22682.1 - 4.3e-08 33.3 0.9 57 4.1 0.0 8.3 1 1 6 10 10 10 1 Transmembrane protein 131-like BspA_v PF18220.1 PVD22682.1 - 2.1 8.4 4.4 24 5.0 0.0 4.4 2 1 3 5 5 5 0 Adhesin BspA variable domain Choline_transpo PF04515.12 PVD22683.1 - 1.9e-95 319.8 37.4 1.9e-95 319.8 37.4 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF4116 PF13475.6 PVD22683.1 - 0.31 10.8 2.1 0.75 9.6 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Acetyltransf_13 PF13880.6 PVD22684.1 - 2.1e-26 91.7 0.0 5.7e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 PVD22684.1 - 9e-15 54.2 0.6 1.9e-14 53.2 0.6 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 PVD22684.1 - 0.004 17.4 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD22684.1 - 0.0084 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.29 PVD22685.1 - 1.6e-47 161.6 0.0 6.4e-47 159.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.29 PVD22685.1 - 3.8e-34 116.3 8.4 8.2e-19 67.2 0.1 3.1 3 0 0 3 3 3 2 KH domain Helicase_C PF00271.31 PVD22685.1 - 1.8e-30 105.5 0.2 9.4e-28 96.8 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain KH_2 PF07650.17 PVD22685.1 - 1.6e-07 31.1 7.5 0.00086 19.1 0.7 3.1 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 PVD22685.1 - 3.7e-07 30.1 0.0 0.019 14.9 0.0 2.9 3 0 0 3 3 3 2 KH-like RNA-binding domain ResIII PF04851.15 PVD22685.1 - 3.7e-05 23.8 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KH_5 PF13184.6 PVD22685.1 - 4e-05 23.6 2.7 0.19 11.8 0.0 2.7 2 0 0 2 2 2 2 NusA-like KH domain CMS1 PF14617.6 PVD22685.1 - 5.5e-05 22.6 0.0 0.00015 21.2 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit KH_4 PF13083.6 PVD22685.1 - 6.5e-05 22.7 3.5 0.34 10.8 0.0 2.9 2 1 0 2 2 2 2 KH domain FANCI_S1-cap PF14674.6 PVD22685.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 cap KH_1 PF00013.29 PVD22686.1 - 1.6e-36 123.9 3.6 3.5e-18 65.2 0.2 2.1 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 PVD22686.1 - 1.9e-09 37.2 2.1 0.0009 19.0 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 PVD22686.1 - 8.8e-05 22.5 2.5 0.16 12.1 0.1 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 PVD22686.1 - 0.00067 19.5 4.4 0.46 10.4 0.2 2.8 2 1 1 3 3 3 2 KH domain SLS PF14611.6 PVD22686.1 - 0.0084 16.0 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator ArfGap PF01412.18 PVD22687.1 - 1.4e-42 144.4 0.1 2.5e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RNA_pol_Rpb5_N PF03871.14 PVD22689.1 - 2.1e-34 118.0 0.1 3.3e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 PVD22689.1 - 9.6e-07 28.6 1.0 5.5e-06 26.2 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain FRG PF08867.11 PVD22689.1 - 0.02 15.9 0.1 0.042 14.8 0.1 1.5 1 0 0 1 1 1 0 FRG domain VWA_2 PF13519.6 PVD22690.1 - 8.8e-05 23.1 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Vps55 PF04133.14 PVD22691.1 - 5.5e-42 142.4 8.6 6.5e-42 142.2 8.6 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 LtrA PF06772.11 PVD22691.1 - 0.0017 17.6 1.0 0.0021 17.4 1.0 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) AAA PF00004.29 PVD22692.1 - 5.9e-96 317.9 0.0 7.5e-47 159.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD22692.1 - 1.2e-23 82.6 4.4 1.9e-11 43.6 0.5 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 PVD22692.1 - 1.8e-21 76.1 1.2 5.9e-21 74.4 0.5 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 PVD22692.1 - 1.4e-13 50.9 0.0 2.3e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PVD22692.1 - 1.9e-13 51.2 0.1 6.1e-05 23.5 0.1 4.2 2 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 PVD22692.1 - 4e-12 45.7 0.0 8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 PVD22692.1 - 1.2e-10 41.8 0.0 6.2e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 PVD22692.1 - 1.6e-10 41.4 0.0 4e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PVD22692.1 - 2.7e-10 40.4 0.1 9.1e-05 22.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD22692.1 - 1.4e-09 38.3 0.2 0.015 15.6 0.1 3.9 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 PVD22692.1 - 1e-08 34.8 0.1 0.0012 18.1 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_18 PF13238.6 PVD22692.1 - 6.9e-08 33.1 0.0 0.014 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PVD22692.1 - 2.8e-07 30.9 0.0 0.0062 16.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 PVD22692.1 - 3.3e-07 29.9 0.1 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PVD22692.1 - 6e-07 29.4 0.1 0.054 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 PVD22692.1 - 1.3e-06 28.5 0.0 0.053 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 PVD22692.1 - 3.3e-06 27.0 0.2 0.00025 21.0 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 PVD22692.1 - 3.4e-06 26.4 0.1 0.036 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 PVD22692.1 - 3.6e-06 27.3 0.1 0.16 12.2 0.0 3.1 3 1 1 4 4 2 2 AAA domain AAA_7 PF12775.7 PVD22692.1 - 4.3e-06 26.4 0.0 0.066 12.7 0.0 3.1 3 1 0 3 3 3 2 P-loop containing dynein motor region ATPase_2 PF01637.18 PVD22692.1 - 8.9e-06 25.8 0.2 0.25 11.2 0.0 3.6 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PVD22692.1 - 1.3e-05 25.7 0.0 0.015 15.8 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 PVD22692.1 - 2.4e-05 24.0 1.9 1.5 8.4 0.0 3.6 2 2 1 4 4 3 2 AAA domain Bac_DnaA PF00308.18 PVD22692.1 - 3e-05 24.0 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 PVD22692.1 - 3.3e-05 23.7 0.0 0.095 12.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 PVD22692.1 - 3.7e-05 23.2 0.2 1.8 7.8 0.0 3.3 3 0 0 3 3 3 2 KaiC TsaE PF02367.17 PVD22692.1 - 5.9e-05 23.1 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 PVD22692.1 - 8.9e-05 22.9 0.0 0.98 9.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 PVD22692.1 - 9.1e-05 22.2 0.0 0.39 10.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 PVD22692.1 - 9.5e-05 21.7 0.0 0.095 11.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 PVD22692.1 - 0.0002 21.3 0.1 0.29 11.0 0.0 3.3 3 1 1 4 4 3 1 NACHT domain NB-ARC PF00931.22 PVD22692.1 - 0.00026 20.3 0.0 0.2 10.8 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain Viral_helicase1 PF01443.18 PVD22692.1 - 0.00045 20.0 0.0 0.005 16.6 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 PVD22692.1 - 0.00054 19.3 0.0 0.55 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 PVD22692.1 - 0.00069 19.7 0.0 0.062 13.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 PVD22692.1 - 0.00076 19.4 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PVD22692.1 - 0.0011 18.5 0.3 1.6 8.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 PVD22692.1 - 0.0011 18.3 0.0 0.41 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 PVD22692.1 - 0.0013 18.8 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 PVD22692.1 - 0.0034 17.2 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PVD22692.1 - 0.0068 16.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 PVD22692.1 - 0.0075 16.6 2.2 2.8 8.2 0.2 3.3 3 1 1 4 4 3 1 AAA domain UFD1 PF03152.14 PVD22692.1 - 0.0096 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SKI PF01202.22 PVD22692.1 - 0.02 15.0 0.1 7.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Shikimate kinase AAA_30 PF13604.6 PVD22692.1 - 0.023 14.4 0.3 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PVD22692.1 - 0.034 14.1 0.2 5.4 6.9 0.0 3.1 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 PVD22692.1 - 0.046 13.5 0.0 9.6 5.9 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 PVD22692.1 - 0.058 13.0 0.1 1.9 8.1 0.0 3.0 3 2 0 3 3 3 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 PVD22692.1 - 0.15 11.8 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 PVD22692.1 - 0.18 12.3 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 PVD22692.1 - 0.19 10.9 0.1 4.3 6.5 0.0 2.7 2 2 1 3 3 3 0 KAP family P-loop domain Patched PF02460.18 PVD22694.1 - 2.7e-44 151.5 15.1 3.4e-38 131.3 0.1 2.7 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 PVD22694.1 - 2.1e-36 125.1 4.1 2.1e-36 125.1 4.1 2.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 PVD22694.1 - 0.0039 16.2 9.6 0.0039 16.2 9.6 2.9 4 0 0 4 4 4 1 MMPL family Hyd_WA PF06462.12 PVD22695.1 - 1.2e-25 89.2 20.6 1.3e-09 37.9 0.5 6.0 6 0 0 6 6 6 5 Propeller Hyd_WA PF06462.12 PVD22696.1 - 1.3e-23 82.7 17.9 5.9e-09 35.8 0.4 5.8 6 1 0 6 6 6 5 Propeller RcnB PF11776.8 PVD22696.1 - 0.038 14.1 0.2 3.6 7.7 0.1 3.6 4 0 0 4 4 4 0 Nickel/cobalt transporter regulator RVT_1 PF00078.27 PVD22697.1 - 2.9e-27 95.6 0.0 1e-26 93.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM132D_C PF15706.5 PVD22699.1 - 0.0054 16.5 5.8 0.48 10.2 0.3 3.6 3 0 0 3 3 3 2 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term 7TM_GPCR_Srw PF10324.9 PVD22700.1 - 3.1e-06 26.7 13.0 3.5e-06 26.5 8.4 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srw PF10324.9 PVD22701.1 - 2.8e-07 30.1 8.8 2.8e-07 30.1 8.8 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD22701.1 - 0.00039 19.8 23.7 0.00063 19.1 23.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4692 PF15763.5 PVD22701.1 - 0.011 16.2 3.9 0.16 12.5 0.3 2.6 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) DUF4448 PF14610.6 PVD22701.1 - 0.31 10.8 0.0 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) YTH PF04146.15 PVD22702.1 - 2.4e-42 144.7 2.7 2.7e-42 144.5 0.0 2.5 2 1 0 2 2 2 1 YT521-B-like domain LRR_4 PF12799.7 PVD22702.1 - 0.00029 21.2 20.4 0.079 13.4 3.0 5.0 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD22702.1 - 4.5 7.1 13.6 35 4.3 0.4 3.9 1 1 2 3 3 3 0 Leucine rich repeat Solute_trans_a PF03619.16 PVD22703.1 - 4.5e-12 46.1 9.1 3.9e-11 43.0 4.2 2.0 2 0 0 2 2 2 2 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 PVD22704.1 - 2e-10 40.7 3.2 2.3e-10 40.5 3.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TraS PF10624.9 PVD22704.1 - 0.21 11.5 0.2 0.27 11.2 0.2 1.1 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Cadherin_3 PF16184.5 PVD22706.1 - 2.6e-71 236.7 8.7 2.2e-26 92.0 0.1 5.7 6 1 0 6 6 6 4 Cadherin-like Cadherin_4 PF17803.1 PVD22706.1 - 0.0088 16.6 2.1 0.25 12.0 0.0 3.3 4 0 0 4 4 4 1 Bacterial cadherin-like domain Big_9 PF17963.1 PVD22706.1 - 0.015 16.0 12.5 0.93 10.3 0.2 4.9 4 2 0 4 4 4 0 Bacterial Ig domain RNase_II_C_S1 PF18614.1 PVD22706.1 - 0.072 13.0 1.2 2.5 8.1 0.2 2.7 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Cadherin_3 PF16184.5 PVD22707.1 - 2.7e-35 120.7 4.6 2.7e-14 53.1 0.2 4.2 3 1 1 4 4 4 3 Cadherin-like Cadherin_4 PF17803.1 PVD22707.1 - 6.6e-06 26.7 1.0 0.077 13.6 0.1 2.9 3 0 0 3 3 3 2 Bacterial cadherin-like domain Big_9 PF17963.1 PVD22707.1 - 1.2e-05 26.0 2.0 1.5 9.6 0.0 4.5 5 0 0 5 5 5 2 Bacterial Ig domain Cadherin_3 PF16184.5 PVD22708.1 - 1.4e-27 95.9 0.7 2.3e-24 85.5 0.1 2.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 PVD22709.1 - 1.1e-32 112.3 1.1 6.8e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Cadherin-like Big_9 PF17963.1 PVD22709.1 - 1.7e-06 28.6 1.2 0.024 15.4 0.0 3.0 2 2 0 2 2 2 2 Bacterial Ig domain Lectin_C PF00059.21 PVD22710.1 - 1.5e-17 64.3 1.4 1.5e-17 64.3 1.4 2.0 3 0 0 3 3 3 1 Lectin C-type domain ADAM_spacer1 PF05986.14 PVD22711.1 - 1.8e-34 118.2 0.0 2.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 PVD22711.1 - 2.5e-08 34.5 7.9 2.5e-08 34.5 7.9 3.6 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain TSP_1 PF00090.19 PVD22711.1 - 4.2e-08 33.3 70.5 3.6e-05 23.9 9.9 5.9 5 2 0 5 5 5 4 Thrombospondin type 1 domain Reprolysin PF01421.19 PVD22712.1 - 1.1e-20 74.3 0.0 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD22712.1 - 1.8e-14 54.3 0.2 2.4e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD22712.1 - 8.7e-12 45.6 0.1 1.4e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD22712.1 - 4.2e-11 42.9 0.1 5.2e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD22712.1 - 4e-10 39.9 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 PVD22712.1 - 0.014 15.7 0.5 0.088 13.0 0.0 2.1 2 0 0 2 2 2 0 Reprolysin family propeptide Peptidase_M10 PF00413.24 PVD22712.1 - 0.016 15.1 0.4 0.044 13.6 0.4 1.7 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 PVD22712.1 - 0.027 13.4 0.2 0.044 12.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Pep_M12B_propep PF01562.19 PVD22713.1 - 4.8e-16 59.3 0.1 6e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 Reprolysin family propeptide FXR_C1 PF16096.5 PVD22713.1 - 0.062 13.5 1.9 0.076 13.2 0.5 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Ank_2 PF12796.7 PVD22714.1 - 7.9e-46 154.6 8.2 1.7e-12 47.8 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.13 PVD22714.1 - 8.5e-46 154.1 20.9 6.9e-28 96.7 5.3 3.8 4 0 0 4 4 4 2 Mib_herc2 SH3_15 PF18346.1 PVD22714.1 - 8e-42 141.4 10.6 2.5e-21 75.7 0.0 3.5 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_4 PF13637.6 PVD22714.1 - 7.9e-37 125.2 10.1 1.4e-11 44.7 0.5 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD22714.1 - 8.8e-36 120.8 19.2 2.9e-07 30.7 0.2 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 PVD22714.1 - 2.3e-35 120.2 12.6 1.2e-09 38.2 0.1 6.7 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD22714.1 - 1.8e-26 89.3 11.2 0.00093 19.5 0.0 9.9 10 0 0 10 10 9 7 Ankyrin repeat zf-C3HC4_3 PF13920.6 PVD22714.1 - 1.9e-25 88.4 68.8 9.3e-11 41.4 11.8 4.6 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 PVD22714.1 - 4.8e-11 42.3 6.9 4.8e-11 42.3 6.9 4.4 4 0 0 4 4 2 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 PVD22714.1 - 9.6e-07 28.6 12.8 9.6e-07 28.6 12.8 4.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Spo0M PF07070.11 PVD22714.1 - 0.17 11.4 0.7 0.34 10.4 0.1 1.7 2 0 0 2 2 2 0 SpoOM protein DUF4314 PF14192.6 PVD22714.1 - 0.21 11.5 5.9 9.8 6.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) Prok-RING_4 PF14447.6 PVD22714.1 - 2.8 7.9 64.9 0.014 15.3 10.8 5.1 4 1 1 5 5 4 0 Prokaryotic RING finger family 4 FKBP_C PF00254.28 PVD22715.1 - 9.8e-28 96.3 0.1 1.1e-27 96.1 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DAO PF01266.24 PVD22716.1 - 2.5e-36 126.0 0.0 3e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PVD22716.1 - 0.11 11.7 0.2 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.27 PVD22717.1 - 2.7e-47 160.4 0.0 5.3e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 PVD22717.1 - 2.7e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain PDZ PF00595.24 PVD22718.1 - 5.5e-14 52.3 0.2 9.6e-14 51.5 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD22718.1 - 0.0001 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD22718.1 - 0.031 14.6 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF4604 PF15377.6 PVD22718.1 - 0.052 14.0 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Pkinase PF00069.25 PVD22719.1 - 6e-23 81.6 0.1 4.6e-22 78.6 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22719.1 - 5.2e-10 39.1 0.3 5.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD22719.1 - 0.071 12.4 0.2 9 5.5 0.1 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 PVD22719.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family BACK PF07707.15 PVD22720.1 - 6.1e-16 58.4 0.5 1.4e-14 54.1 0.2 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 PVD22720.1 - 3e-12 46.8 0.6 1e-10 41.8 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain Leuk-A4-hydro_C PF09127.11 PVD22721.1 - 7.1e-11 42.2 0.9 1.8e-10 40.9 0.0 2.1 3 0 0 3 3 3 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 PVD22721.1 - 7.6e-09 35.5 0.9 1.4e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD22721.1 - 3.3e-05 24.1 0.0 6.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain LRRNT_2 PF08263.12 PVD22721.1 - 4.9 7.6 5.8 17 5.8 1.3 2.7 1 1 1 2 2 2 0 Leucine rich repeat N-terminal domain ANAPC4_WD40 PF12894.7 PVD22723.1 - 1.4e-10 41.3 0.1 1.4e-05 25.3 0.0 4.0 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD22723.1 - 4e-07 30.6 13.7 0.0021 18.8 0.1 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_3 PF13570.6 PVD22723.1 - 0.062 13.8 0.0 0.41 11.2 0.0 2.5 1 0 0 1 1 1 0 PQQ-like domain NpwBP PF12622.7 PVD22723.1 - 0.14 13.0 0.2 0.45 11.3 0.2 1.9 1 0 0 1 1 1 0 mRNA biogenesis factor WD40 PF00400.32 PVD22724.1 - 5e-18 65.1 5.2 0.0019 19.0 0.2 9.4 10 0 0 10 10 9 2 WD domain, G-beta repeat ATG16 PF08614.11 PVD22724.1 - 8.7e-05 22.8 45.5 0.00031 21.0 7.3 5.1 1 1 5 6 6 4 2 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 PVD22724.1 - 0.00096 19.2 10.2 0.00096 19.2 10.2 5.7 2 2 3 6 6 5 2 Laminin Domain II KASH_CCD PF14662.6 PVD22724.1 - 0.0018 18.1 17.9 0.0018 18.1 17.9 4.8 1 1 4 5 5 3 1 Coiled-coil region of CCDC155 or KASH MPS2 PF17060.5 PVD22724.1 - 0.0019 17.5 20.0 0.0019 17.5 20.0 4.4 1 1 3 4 4 1 1 Monopolar spindle protein 2 CALCOCO1 PF07888.11 PVD22724.1 - 0.002 17.1 19.6 0.002 17.1 19.6 3.3 1 1 2 3 3 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.10 PVD22724.1 - 0.0042 17.3 8.0 0.0042 17.3 8.0 6.8 1 1 6 7 7 6 3 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 PVD22724.1 - 0.0048 16.9 11.1 0.0048 16.9 11.1 6.0 1 1 4 5 5 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ANAPC4_WD40 PF12894.7 PVD22724.1 - 0.0059 16.9 1.0 5 7.5 0.1 5.2 5 4 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TMF_DNA_bd PF12329.8 PVD22724.1 - 0.012 15.6 10.2 0.012 15.6 10.2 9.5 3 3 8 12 12 10 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 PVD22724.1 - 0.014 16.0 8.1 0.014 16.0 8.1 7.3 2 2 6 8 8 6 0 Initiation control protein YabA Trans_reg_C PF00486.28 PVD22724.1 - 0.15 12.2 2.6 19 5.4 0.1 3.5 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal ubiquitin PF00240.23 PVD22725.1 - 0.0012 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Steroid_dh PF02544.16 PVD22725.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DnaJ PF00226.31 PVD22725.1 - 0.05 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain Tctex-1 PF03645.13 PVD22726.1 - 1.2e-22 80.1 0.4 2e-22 79.3 0.4 1.4 1 0 0 1 1 1 1 Tctex-1 family PAR1 PF06521.11 PVD22727.1 - 0.1 12.2 4.4 1.2 8.7 0.5 2.0 1 1 1 2 2 2 0 PAR1 protein SH3_9 PF14604.6 PVD22729.1 - 0.0056 16.5 0.4 0.014 15.3 0.4 1.7 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22729.1 - 0.0061 16.1 0.4 0.021 14.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain RVT_1 PF00078.27 PVD22731.1 - 9e-18 64.6 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3K_P85_iSH2 PF16454.5 PVD22732.1 - 1.2e-36 125.8 18.7 2.1e-36 124.9 18.7 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 PVD22732.1 - 2.4e-31 107.6 0.0 3.6e-18 65.4 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 PVD22732.1 - 1.2e-24 86.9 0.2 5e-24 84.9 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain SAM_2 PF07647.17 PVD22732.1 - 1.8e-12 47.1 0.1 4.7e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD22732.1 - 6.5e-11 42.5 0.2 1.4e-10 41.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 PVD22732.1 - 1.9e-10 40.5 10.3 1.9e-10 40.5 10.3 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4200 PF13863.6 PVD22732.1 - 0.015 15.7 8.5 0.015 15.7 8.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF5596 PF18082.1 PVD22732.1 - 0.043 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Not3 PF04065.15 PVD22732.1 - 0.55 9.6 17.4 0.2 11.1 6.5 2.8 2 1 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component DUF724 PF05266.14 PVD22732.1 - 1.2 8.9 13.2 0.63 9.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 PVD22732.1 - 1.4 6.7 7.5 2 6.2 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 PVD22732.1 - 7.2 5.8 14.6 0.66 9.2 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Linker_histone PF00538.19 PVD22733.1 - 5.1e-30 103.7 0.6 1.3e-29 102.3 0.6 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family SH2 PF00017.24 PVD22734.1 - 1.7e-19 69.7 0.0 2.7e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 SH2 domain PI3K_P85_iSH2 PF16454.5 PVD22734.1 - 0.083 12.5 16.5 0.12 11.9 16.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nod1 PF17114.5 PVD22734.1 - 0.18 11.9 3.1 0.31 11.2 3.1 1.3 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF16 PF01519.16 PVD22734.1 - 2.1 8.9 7.1 0.97 10.0 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 SH2 PF00017.24 PVD22735.1 - 2.8e-24 85.0 0.0 1.6e-12 47.3 0.0 3.0 3 0 0 3 3 3 2 SH2 domain PI3K_P85_iSH2 PF16454.5 PVD22735.1 - 0.0012 18.4 12.7 0.0018 17.9 12.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4530 PF15039.6 PVD22735.1 - 0.16 12.1 4.7 0.11 12.7 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) SH2 PF00017.24 PVD22736.1 - 4.1e-21 74.9 0.0 6.1e-12 45.5 0.0 2.8 2 0 0 2 2 2 2 SH2 domain PI3K_P85_iSH2 PF16454.5 PVD22736.1 - 6e-06 26.0 14.3 1.6e-05 24.5 14.3 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Na_trans_assoc PF06512.13 PVD22736.1 - 0.24 11.6 6.3 0.4 10.9 6.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Pkinase PF00069.25 PVD22737.1 - 2.4e-54 184.5 0.3 4.4e-54 183.6 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 PVD22737.1 - 7.1e-34 115.8 0.8 2.6e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Pkinase_Tyr PF07714.17 PVD22737.1 - 7e-29 100.9 0.1 1.2e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD22737.1 - 1.7e-06 27.1 0.0 5.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF4524 PF15025.6 PVD22737.1 - 7.9e-05 22.4 0.0 0.01 15.6 0.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4524) Kinase-like PF14531.6 PVD22737.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD22737.1 - 0.061 13.2 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family LrgA PF03788.14 PVD22738.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 LrgA family Nuc_sug_transp PF04142.15 PVD22740.1 - 6.9e-81 271.8 8.2 9.5e-81 271.4 8.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PVD22740.1 - 8.4e-06 26.0 17.5 2.6e-05 24.4 6.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PVD22740.1 - 3.9e-05 23.0 2.4 6e-05 22.4 2.4 1.4 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 PVD22740.1 - 0.00054 19.3 9.5 0.00079 18.7 9.5 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 PVD22740.1 - 0.0081 15.8 1.6 0.0081 15.8 1.6 1.9 1 1 0 2 2 2 1 Putative multidrug resistance efflux transporter Aminotran_1_2 PF00155.21 PVD22741.1 - 8.1e-41 140.4 0.0 9.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sel1 PF08238.12 PVD22743.1 - 6.6e-16 58.4 6.1 0.00077 20.1 0.0 4.6 4 0 0 4 4 4 4 Sel1 repeat Tup_N PF08581.10 PVD22743.1 - 0.16 12.3 2.6 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 Tup N-terminal Bac_rhamnosid6H PF17389.2 PVD22744.1 - 0.004 16.4 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 7tm_2 PF00002.24 PVD22745.1 - 4.3e-39 134.3 7.5 7.6e-39 133.5 7.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.18 PVD22745.1 - 6.1e-21 74.6 3.5 1.4e-20 73.5 1.8 2.4 2 0 0 2 2 2 1 Galactose binding lectin domain GAIN PF16489.5 PVD22745.1 - 3.8e-12 46.1 0.1 6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain HRM PF02793.22 PVD22745.1 - 1.5e-06 28.4 3.0 1.8e-06 28.2 0.5 2.6 2 0 0 2 2 2 1 Hormone receptor domain fn3 PF00041.21 PVD22745.1 - 0.00094 19.5 0.1 0.44 10.9 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Dicty_CAR PF05462.11 PVD22745.1 - 0.62 9.1 5.3 0.97 8.5 5.3 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor SP_C-Propep PF08999.10 PVD22746.1 - 0.034 13.9 0.8 0.072 12.9 0.8 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide COesterase PF00135.28 PVD22747.1 - 1.3e-27 96.8 0.0 1.6e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 PVD22748.1 - 4e-49 167.9 0.0 8.6e-49 166.8 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family COesterase PF00135.28 PVD22749.1 - 3.6e-11 42.6 0.1 4.6e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family CoA_binding_3 PF13727.6 PVD22749.1 - 0.018 15.1 0.1 0.018 15.0 0.1 1.0 1 0 0 1 1 1 0 CoA-binding domain COesterase PF00135.28 PVD22750.1 - 2.2e-12 46.7 0.0 3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Chorion_3 PF05387.11 PVD22751.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Chorion family 3 COesterase PF00135.28 PVD22752.1 - 2.5e-21 76.2 0.0 3.8e-17 62.3 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family LST1 PF05083.13 PVD22752.1 - 0.021 15.1 0.3 0.021 15.1 0.3 2.0 2 0 0 2 2 2 0 LST-1 protein Glyco_transf_17 PF04724.13 PVD22752.1 - 0.17 10.9 0.1 0.33 9.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 17 Rhabdo_glycop PF00974.18 PVD22752.1 - 0.25 9.7 0.4 0.38 9.2 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EF-hand_7 PF13499.6 PVD22753.1 - 3.5e-23 81.8 1.1 1.9e-13 50.6 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD22753.1 - 8.4e-21 71.9 1.1 2.3e-06 26.7 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PVD22753.1 - 1.1e-18 65.4 0.6 5.5e-05 22.8 0.1 5.3 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 PVD22753.1 - 5.9e-17 61.3 0.2 8.9e-07 28.7 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD22753.1 - 6.8e-16 57.0 1.8 8.5e-05 21.9 0.2 4.2 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 PVD22753.1 - 0.00011 22.5 0.3 0.33 11.3 0.2 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD22753.1 - 0.0021 18.0 2.0 2.2 8.2 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PVD22753.1 - 0.013 15.3 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 PVD22753.1 - 0.084 13.2 0.0 6.2 7.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 PVD22753.1 - 0.19 11.9 0.0 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_7 PF13499.6 PVD22754.1 - 2.7e-23 82.2 1.9 3.7e-13 49.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD22754.1 - 3.7e-20 69.9 4.9 8.4e-07 28.1 0.1 4.8 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 PVD22754.1 - 2.6e-18 64.3 0.7 2.5e-05 23.8 0.2 5.3 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 PVD22754.1 - 4.2e-17 60.8 3.4 1.7e-05 24.1 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD22754.1 - 2.5e-16 59.3 1.4 3.8e-07 29.9 0.0 4.0 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD22754.1 - 0.0001 22.6 0.2 0.4 11.0 0.0 3.0 2 2 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD22754.1 - 0.0056 16.6 3.0 2.2 8.3 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PVD22754.1 - 0.012 15.5 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 PVD22755.1 - 3.7e-20 72.2 2.3 3.9e-12 46.4 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD22755.1 - 3.1e-17 61.0 1.3 0.00024 20.8 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PVD22755.1 - 3.4e-17 60.6 3.3 3e-05 23.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD22755.1 - 5.2e-11 42.2 0.6 0.00042 20.1 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD22755.1 - 2.2e-07 30.0 1.8 0.1 12.1 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_13 PF17958.1 PVD22755.1 - 0.032 14.0 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD22755.1 - 0.094 13.0 0.3 3.6 8.0 0.1 2.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 PVD22755.1 - 0.11 12.4 0.0 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 EF hand LRR_8 PF13855.6 PVD22756.1 - 2.1e-16 59.4 5.8 6.6e-08 32.2 0.0 4.3 4 1 0 5 5 5 3 Leucine rich repeat TIR PF01582.20 PVD22756.1 - 5.2e-11 42.7 0.0 7.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 PVD22756.1 - 1.4e-08 35.3 0.0 5.8e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 PVD22756.1 - 3.1e-07 30.1 0.6 0.0027 17.3 0.2 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 PVD22756.1 - 1.3e-05 25.5 7.4 0.29 11.6 0.2 5.9 3 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRRCT PF01463.24 PVD22756.1 - 0.0011 19.3 0.4 0.0045 17.4 0.4 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRRNT PF01462.18 PVD22756.1 - 0.0018 17.8 4.3 0.0018 17.8 4.3 3.7 4 1 0 4 4 4 1 Leucine rich repeat N-terminal domain Nuc_deoxyri_tr2 PF15891.5 PVD22756.1 - 0.038 14.3 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF1068 PF06364.12 PVD22756.1 - 0.074 12.9 1.9 0.2 11.5 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) LRR_1 PF00560.33 PVD22756.1 - 0.81 10.5 4.6 1e+02 4.1 0.0 6.1 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD22757.1 - 5e-21 74.2 3.7 3.1e-09 36.5 0.0 4.3 3 1 1 4 4 4 3 Leucine rich repeat TIR PF01582.20 PVD22757.1 - 2.5e-10 40.4 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD22757.1 - 1.2e-08 35.1 6.4 0.001 19.4 0.1 4.4 3 1 2 5 5 4 3 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD22757.1 - 2.1e-08 34.8 0.0 4.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD22757.1 - 1.1e-06 28.2 0.3 0.046 13.2 0.1 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PVD22757.1 - 0.0017 18.7 4.7 11 7.1 0.1 6.2 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_5 PF13306.6 PVD22757.1 - 0.048 13.6 0.0 0.18 11.8 0.0 2.0 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PVD22757.1 - 0.051 13.6 8.7 5.4 7.3 0.1 5.4 7 1 1 8 8 8 0 Leucine Rich repeat LRRCT PF01463.24 PVD22757.1 - 0.084 13.5 0.8 0.44 11.2 0.1 2.8 3 0 0 3 3 2 0 Leucine rich repeat C-terminal domain Orthoreo_P10 PF07204.11 PVD22757.1 - 0.14 12.1 0.1 5.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 LRRNT PF01462.18 PVD22757.1 - 0.95 9.2 9.2 1.1 9.0 2.3 3.9 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PVD22758.1 - 5.1e-22 77.4 2.7 2.3e-10 40.1 0.0 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD22758.1 - 1.4e-11 44.4 5.2 9.3e-05 22.7 0.0 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD22758.1 - 2.1e-10 40.7 0.0 3.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD22758.1 - 1.3e-08 34.6 1.4 0.00092 18.8 0.2 2.3 2 0 0 2 2 2 2 Leucine-rich repeat TIR_2 PF13676.6 PVD22758.1 - 2.3e-08 34.7 0.0 5.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD22758.1 - 1.5e-05 24.9 0.7 13 6.8 0.2 6.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRRNT PF01462.18 PVD22758.1 - 0.0039 16.8 1.5 0.0039 16.8 1.5 3.4 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain Orthoreo_P10 PF07204.11 PVD22758.1 - 0.004 17.1 0.1 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 Orthoreovirus membrane fusion protein p10 LRR_6 PF13516.6 PVD22758.1 - 0.042 13.9 8.1 7.7 6.9 0.1 5.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 PVD22759.1 - 1.4e-20 72.8 9.2 9.1e-09 35.0 0.0 5.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PVD22759.1 - 9.4e-13 48.1 11.1 0.00049 20.4 0.0 6.4 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD22759.1 - 3.5e-06 26.6 2.8 0.093 12.2 0.2 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 PVD22759.1 - 3.5e-06 26.8 3.1 9.7 7.2 0.0 6.9 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 PVD22759.1 - 0.0013 18.6 8.3 5.2 7.4 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRRNT PF01462.18 PVD22759.1 - 1 9.1 11.2 0.19 11.4 2.9 3.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain TIR PF01582.20 PVD22760.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD22760.1 - 4.3e-09 37.0 0.0 6.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain Nuc_deoxyri_tr2 PF15891.5 PVD22760.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Flp1_like PF16982.5 PVD22760.1 - 5.2 6.5 6.6 9.7 5.7 6.6 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain TatD_DNase PF01026.21 PVD22761.1 - 1.6e-45 155.5 0.0 2.4e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase LRR_8 PF13855.6 PVD22761.1 - 1.5e-28 98.3 8.6 1.4e-09 37.6 0.0 4.6 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD22761.1 - 9.7e-12 44.9 12.4 0.00043 20.6 0.2 5.5 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD22761.1 - 1.6e-10 41.1 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD22761.1 - 9e-09 36.0 0.0 6.3e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 PVD22761.1 - 4e-07 29.7 0.3 0.01 15.4 0.0 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PVD22761.1 - 0.0003 20.9 5.6 25 5.9 0.0 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_5 PF13306.6 PVD22761.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 PVD22761.1 - 0.092 12.4 5.1 0.41 10.4 2.9 3.3 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PVD22761.1 - 3.7 7.8 16.1 10 6.5 0.1 5.8 7 0 0 7 7 7 0 Leucine Rich repeat TMEM214 PF10151.9 PVD22762.1 - 4.3e-144 481.5 0.5 5.4e-144 481.2 0.5 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator TRC8_N PF13705.6 PVD22762.1 - 0.019 13.9 5.5 0.019 13.9 2.3 2.3 2 2 1 3 3 3 0 TRC8 N-terminal domain Spc7 PF08317.11 PVD22763.1 - 0.00047 19.1 23.8 0.00047 19.1 23.8 4.7 1 1 3 4 4 4 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PVD22763.1 - 0.0063 16.6 20.9 0.0063 16.6 20.9 6.5 2 2 5 7 7 7 3 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 PVD22763.1 - 0.19 11.5 86.3 0.087 12.6 17.9 4.6 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 PVD22763.1 - 0.28 10.2 69.1 0.042 12.9 19.5 4.1 1 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 PVD22763.1 - 0.44 11.1 93.4 1.2 9.6 14.6 5.5 1 1 3 4 4 4 0 Apg6 coiled-coil region HsbA PF12296.8 PVD22763.1 - 7.5 7.0 8.9 62 4.0 0.1 5.0 4 3 1 5 5 5 0 Hydrophobic surface binding protein A HABP4_PAI-RBP1 PF04774.15 PVD22764.1 - 9.5e-31 107.0 12.2 9.5e-31 107.0 12.2 4.0 4 1 0 4 4 4 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 PVD22764.1 - 2.1e-14 54.5 21.5 2.1e-14 54.5 21.5 3.1 1 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal zf-H2C2_2 PF13465.6 PVD22765.1 - 2.6e-05 24.4 1.6 2.6e-05 24.4 1.6 3.4 4 0 0 4 4 4 2 Zinc-finger double domain DUF5526 PF17664.1 PVD22765.1 - 9.5e-05 22.0 2.3 0.00013 21.5 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5526) zf-C2H2 PF00096.26 PVD22765.1 - 0.00091 19.6 1.4 0.00091 19.6 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type HMG_box_5 PF14887.6 PVD22765.1 - 0.039 13.9 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 PRONE PF03759.13 PVD22765.1 - 0.063 12.1 2.1 0.081 11.7 2.1 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) IF-2B PF01008.17 PVD22766.1 - 6.1e-54 183.1 0.0 7.4e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4370 PF14290.6 PVD22766.1 - 0.0062 16.4 0.1 0.0091 15.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4370) Cys_Met_Meta_PP PF01053.20 PVD22767.1 - 6.8e-101 337.6 0.0 2.1e-63 214.2 0.0 3.1 1 1 2 3 3 3 3 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PVD22767.1 - 3.5e-05 22.9 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 PVD22767.1 - 0.031 12.8 0.0 0.077 11.5 0.0 1.5 2 0 0 2 2 2 0 Methionine gamma-lyase CABIT PF12736.7 PVD22768.1 - 1.5e-35 122.8 0.1 6.9e-35 120.7 0.0 1.9 2 0 0 2 2 2 1 Cell-cycle sustaining, positive selection, Hce2 PF14856.6 PVD22769.1 - 0.15 12.4 0.5 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor Sulfotransfer_2 PF03567.14 PVD22770.1 - 1.9e-23 83.7 12.5 9.6e-21 74.8 2.0 3.0 3 0 0 3 3 3 2 Sulfotransferase family AJAP1_PANP_C PF15298.6 PVD22770.1 - 0.18 12.0 6.6 0.38 10.9 6.6 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus SSP160 PF06933.11 PVD22770.1 - 1.9 6.6 6.7 2.7 6.1 6.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ldl_recept_a PF00057.18 PVD22771.1 - 2.6e-88 289.9 160.4 3e-12 46.5 14.9 8.9 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 PVD22771.1 - 4.4e-48 161.5 8.7 3.4e-13 49.8 0.0 5.5 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD22771.1 - 1.5e-15 57.2 44.7 2.7e-08 33.9 9.2 7.6 7 2 2 9 9 3 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 PVD22771.1 - 6.7e-08 32.4 4.5 1.2e-05 25.1 4.0 4.3 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 PVD22771.1 - 1.8e-07 31.0 36.6 8.8e-05 22.4 0.2 6.4 6 0 0 6 6 5 3 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD22771.1 - 2.8e-07 30.6 7.3 2.8e-07 30.6 7.3 12.5 5 3 4 9 9 4 1 Calcium-binding EGF domain TMEM154 PF15102.6 PVD22771.1 - 1.2e-05 25.2 0.2 3.2e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF5050 PF16472.5 PVD22771.1 - 1.8e-05 24.1 0.0 8.1e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) RIFIN PF02009.16 PVD22771.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Rifin IgaA PF07095.11 PVD22771.1 - 0.0057 14.7 0.0 0.0081 14.2 0.0 1.1 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA DUF4448 PF14610.6 PVD22771.1 - 0.0093 15.8 0.2 0.0093 15.8 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 PVD22771.1 - 0.01 16.0 2.3 0.022 14.9 2.3 1.5 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 PVD22771.1 - 0.043 13.9 0.1 0.043 13.9 0.1 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4366) EphA2_TM PF14575.6 PVD22771.1 - 0.085 13.8 0.2 0.42 11.5 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 PVD22771.1 - 0.086 13.4 1.2 0.2 12.3 1.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2207 PF09972.9 PVD22771.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 PVD22771.1 - 0.18 11.9 1.5 0.37 10.9 1.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Trp_oprn_chp PF09534.10 PVD22771.1 - 0.2 11.4 0.9 0.27 11.0 0.1 1.5 2 0 0 2 2 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FixQ PF05545.11 PVD22771.1 - 0.99 9.4 3.2 0.42 10.6 0.5 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Flp1_like PF16982.5 PVD22771.1 - 8.4 5.9 7.7 22 4.6 5.0 2.4 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain AhpC-TSA_2 PF13911.6 PVD22772.1 - 9.6e-14 51.5 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PVD22772.1 - 0.0037 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DSPn PF14671.6 PVD22773.1 - 2.4e-64 216.0 1.0 6.9e-63 211.3 0.7 2.5 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 PVD22773.1 - 5.4e-14 52.1 0.2 1.3e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD22773.1 - 0.00013 21.6 0.1 0.00024 20.8 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PVD22773.1 - 0.0052 16.9 0.0 0.012 15.8 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD22773.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CECR6_TMEM121 PF14997.6 PVD22774.1 - 0.0092 15.8 3.4 0.014 15.3 3.4 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family ARD PF03079.14 PVD22776.1 - 3e-34 118.5 0.1 3.7e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 PVD22776.1 - 1.5e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 PVD22776.1 - 0.0068 16.3 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain BTB_2 PF02214.22 PVD22777.1 - 9.8e-16 57.9 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain NeA_P2 PF12312.8 PVD22778.1 - 0.0096 15.4 3.5 0.012 15.1 3.5 1.3 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein CAP_N PF01213.19 PVD22778.1 - 0.018 14.5 6.2 0.019 14.5 6.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PVD22778.1 - 1.8 8.6 16.3 0.55 10.3 12.7 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 PVD22778.1 - 2.4 8.2 15.3 0.87 9.6 12.9 1.5 1 1 1 2 2 2 0 Mitochondrial fission regulator BTB_2 PF02214.22 PVD22779.1 - 0.00054 20.3 0.0 0.0021 18.4 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans PF00520.31 PVD22780.1 - 1.1e-41 142.7 18.6 1.3e-41 142.5 18.6 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD22780.1 - 1.3e-11 44.3 8.2 1.3e-11 44.3 8.2 2.4 3 0 0 3 3 3 1 Ion channel DUF423 PF04241.15 PVD22780.1 - 0.082 13.1 0.4 0.26 11.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Peptidase_A24 PF01478.18 PVD22780.1 - 4.8 7.6 9.5 6.1 7.3 8.5 1.7 1 1 0 1 1 1 0 Type IV leader peptidase family ELO PF01151.18 PVD22781.1 - 1.1e-59 202.0 30.2 1.2e-59 201.8 30.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Tetraspanin PF00335.20 PVD22781.1 - 1.5 8.5 9.7 0.058 13.1 3.2 2.0 2 0 0 2 2 2 0 Tetraspanin family ELO PF01151.18 PVD22782.1 - 2.7e-14 53.3 10.8 5.2e-09 36.0 3.4 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family Tetraspanin PF00335.20 PVD22782.1 - 0.015 15.0 6.2 0.02 14.6 6.2 1.3 1 0 0 1 1 1 0 Tetraspanin family ELO PF01151.18 PVD22784.1 - 7.9e-60 202.5 20.4 9.4e-60 202.2 20.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Ion_trans PF00520.31 PVD22785.1 - 4e-36 124.5 21.2 5.3e-36 124.1 21.2 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD22785.1 - 4e-23 81.6 0.0 8.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD22785.1 - 1.9e-10 40.5 8.6 1.9e-10 40.5 8.6 2.0 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 PVD22785.1 - 0.002 18.2 0.0 0.0086 16.2 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_A24 PF01478.18 PVD22785.1 - 0.38 11.2 5.2 0.95 9.9 5.2 1.7 1 0 0 1 1 1 0 Type IV leader peptidase family FHA PF00498.26 PVD22786.1 - 2.7e-14 53.3 0.2 3.9e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 FHA domain Plectin PF00681.20 PVD22787.1 - 1e-232 751.8 61.8 9.6e-05 22.2 0.0 92.5 79 20 24 103 103 102 50 Plectin repeat Spectrin PF00435.21 PVD22787.1 - 3.9e-195 634.8 376.3 3.3e-13 50.0 1.2 42.0 39 4 5 44 44 44 31 Spectrin repeat CH PF00307.31 PVD22787.1 - 2.3e-38 130.7 0.0 5.1e-21 74.9 0.0 3.3 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 PVD22787.1 - 8.2e-32 109.1 1.0 2.1e-31 107.8 1.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SH3_10 PF17902.1 PVD22787.1 - 3.3e-16 59.1 0.3 1e-15 57.5 0.3 2.0 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 PVD22787.1 - 9.9e-10 37.3 3.0 3.8e-05 22.9 0.2 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD22787.1 - 1.2e-09 38.4 1.2 9.5e-09 35.6 1.2 2.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD22787.1 - 1.6e-08 33.8 0.8 0.0011 18.7 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain OCRE PF17780.1 PVD22787.1 - 4.9e-07 29.7 4.8 32 4.7 0.0 10.9 12 0 0 12 12 11 0 OCRE domain EF-hand_5 PF13202.6 PVD22787.1 - 0.00016 21.0 4.4 0.3 10.7 0.5 3.1 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 PVD22787.1 - 0.0002 21.1 0.0 0.0019 18.0 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_8 PF13833.6 PVD22787.1 - 0.00032 20.5 1.1 0.0023 17.7 0.5 2.7 1 1 1 2 2 2 2 EF-hand domain pair ATP-gua_PtransN PF02807.15 PVD22787.1 - 0.00066 20.0 3.0 37 4.8 0.0 8.5 7 1 0 7 7 5 0 ATP:guanido phosphotransferase, N-terminal domain Occludin_ELL PF07303.13 PVD22787.1 - 0.0016 19.1 0.5 0.0016 19.1 0.5 18.4 19 4 2 21 21 18 1 Occludin homology domain Spectrin_like PF18373.1 PVD22787.1 - 0.0032 17.5 4.0 0.0095 16.0 0.5 4.0 2 0 0 2 2 2 1 Spectrin like domain Fic PF02661.18 PVD22787.1 - 6.8 7.7 13.5 1.7e+02 3.2 0.0 7.9 7 0 0 7 7 7 0 Fic/DOC family SH2 PF00017.24 PVD22788.1 - 2.4e-10 40.4 0.0 3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.17 PVD22789.1 - 1.1e-84 283.8 0.1 1.5e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD22789.1 - 3e-44 151.4 0.0 4.7e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD22789.1 - 3e-13 49.7 0.1 8.1e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 PVD22789.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PVD22789.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NfI_DNAbd_pre-N PF10524.9 PVD22790.1 - 4.2e-26 90.5 3.8 7.4e-26 89.7 3.8 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 PVD22790.1 - 3.8e-12 46.3 0.4 8.3e-12 45.2 0.4 1.6 1 0 0 1 1 1 1 MH1 domain Gemini_AC4_5_2 PF08464.10 PVD22791.1 - 0.15 12.0 1.0 0.38 10.7 0.2 2.1 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region DUF1155 PF06633.11 PVD22792.1 - 0.9 9.1 0.0 0.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) TPT PF03151.16 PVD22794.1 - 2.7e-13 50.0 11.4 3.6e-13 49.5 11.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PVD22794.1 - 7.2e-06 25.4 11.9 1e-05 24.9 11.9 1.3 1 0 0 1 1 1 1 UAA transporter family CS PF04969.16 PVD22795.1 - 0.019 15.9 0.0 0.068 14.2 0.0 1.7 2 0 0 2 2 2 0 CS domain ETX_MTX2 PF03318.13 PVD22796.1 - 0.0016 18.3 3.7 0.0019 18.0 3.7 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 ETX_MTX2 PF03318.13 PVD22797.1 - 0.0061 16.4 0.2 0.01 15.7 0.2 1.4 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF2102 PF09875.9 PVD22797.1 - 0.071 12.8 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) DUF5538 PF17692.1 PVD22800.1 - 1.2 9.3 5.0 8 6.5 0.1 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5538) GTP_EFTU PF00009.27 PVD22801.1 - 7.4e-51 172.5 0.0 1.4e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 PVD22801.1 - 1.6e-13 50.7 0.3 1.6e-13 50.7 0.3 2.1 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 PVD22801.1 - 3.6e-11 43.4 0.1 5.1e-10 39.6 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 PVD22801.1 - 1.6e-07 31.4 0.0 0.00011 22.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 PVD22801.1 - 0.00064 20.1 0.2 0.0013 19.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 PVD22801.1 - 0.015 14.9 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Ras family cobW PF02492.19 PVD22801.1 - 0.019 14.5 0.2 2 8.0 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 PVD22801.1 - 0.032 14.4 0.2 6.9 6.9 0.0 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD22801.1 - 0.034 14.4 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 PVD22801.1 - 0.16 11.5 1.0 6.3 6.3 0.4 3.0 2 1 0 2 2 2 0 Ferrous iron transport protein B Ham1p_like PF01725.16 PVD22802.1 - 4.9e-54 183.1 0.0 5.5e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family FAM110_C PF14160.6 PVD22806.1 - 6.1e-19 69.1 4.1 6.1e-19 69.1 4.1 2.9 3 1 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.6 PVD22806.1 - 0.073 13.3 1.3 0.14 12.4 0.1 2.1 2 1 0 2 2 2 0 Centrosome-associated N terminus CAP_GLY PF01302.25 PVD22807.1 - 4.5e-77 254.0 6.7 3.6e-26 91.0 0.6 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.7 PVD22807.1 - 8.5e-14 51.9 1.0 3.4e-11 43.6 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD22807.1 - 1.1e-12 47.9 3.2 0.001 19.3 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD22807.1 - 3.2e-12 46.7 1.3 1.4e-06 28.7 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD22807.1 - 9.3e-11 41.7 6.9 0.015 15.7 0.5 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD22807.1 - 7.1e-10 38.3 1.7 0.056 14.0 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat DHR-2 PF06920.13 PVD22808.1 - 4.3e-172 573.5 9.7 9e-160 532.8 4.7 2.2 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 PVD22808.1 - 5.7e-32 111.1 0.3 3.1e-26 92.4 0.0 2.8 2 1 1 3 3 3 2 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 PVD22808.1 - 2.9e-27 95.3 1.5 2.1e-26 92.5 1.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 PVD22808.1 - 6.3e-06 25.4 1.6 1.2e-05 24.5 0.5 1.9 2 0 0 2 2 2 1 DOCK N-terminus DUF1686 PF07937.11 PVD22808.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) F-box-like PF12937.7 PVD22809.1 - 2.4e-09 36.9 2.3 5.3e-09 35.8 2.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD22809.1 - 4.4e-08 32.8 2.6 1.1e-07 31.5 2.6 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD22809.1 - 7.2e-05 22.6 1.1 0.0056 16.6 0.5 2.3 2 0 0 2 2 2 1 F-box Arf PF00025.21 PVD22809.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PRANC PF09372.10 PVD22809.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 PRANC domain EF-hand_7 PF13499.6 PVD22810.1 - 1.2e-22 80.2 17.4 7.5e-11 42.3 2.6 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD22810.1 - 1.1e-15 55.9 24.9 0.00027 20.3 0.6 6.5 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 PVD22810.1 - 1.9e-14 52.2 21.0 0.00059 19.6 0.1 6.4 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 PVD22810.1 - 1.5e-11 43.9 23.1 0.0021 17.9 3.6 5.6 3 2 2 5 5 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD22810.1 - 2e-06 28.1 4.9 0.0061 16.9 0.7 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD22810.1 - 3.3e-06 27.2 3.4 0.018 15.2 0.2 2.8 2 0 0 2 2 2 2 Dockerin type I domain RVT_3 PF13456.6 PVD22810.1 - 0.0027 17.5 0.5 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase-like DUF4777 PF16007.5 PVD22810.1 - 0.0033 17.7 0.0 4.5 7.6 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4777) EF-hand_4 PF12763.7 PVD22810.1 - 0.014 15.4 14.0 1 9.4 0.6 4.0 1 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Glycos_trans_3N PF02885.17 PVD22810.1 - 0.015 15.1 1.0 7.1 6.6 0.0 2.9 2 1 1 3 3 3 0 Glycosyl transferase family, helical bundle domain DUF1425 PF07233.12 PVD22810.1 - 0.037 13.9 0.0 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1425) PB1 PF00564.24 PVD22810.1 - 0.074 13.0 0.1 17 5.4 0.1 2.9 2 1 0 2 2 2 0 PB1 domain DEK_C PF08766.11 PVD22810.1 - 0.19 11.7 11.2 1.3 9.0 0.0 3.4 4 0 0 4 4 3 0 DEK C terminal domain DUF3349 PF11829.8 PVD22810.1 - 0.6 10.9 2.0 40 5.1 0.2 3.3 2 2 3 5 5 5 0 Protein of unknown function (DUF3349) EF-hand_5 PF13202.6 PVD22810.1 - 2.4 7.8 14.0 3.4 7.3 0.4 4.5 4 0 0 4 4 4 0 EF hand DUF2475 PF10629.9 PVD22811.1 - 1.4e-31 108.5 4.6 2.7e-31 107.6 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) PTPlike_phytase PF14566.6 PVD22811.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate ketoacyl-synt PF00109.26 PVD22812.1 - 4.7e-87 291.7 0.1 1.1e-86 290.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 PVD22812.1 - 1.2e-45 156.4 0.0 1.9e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 PVD22812.1 - 5.9e-34 116.6 0.1 1.7e-33 115.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 PVD22812.1 - 8.6e-34 117.1 0.1 2.1e-33 115.9 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 PVD22812.1 - 1.1e-17 64.5 0.0 3e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 PVD22812.1 - 3.3e-07 29.9 0.2 6e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 PVD22813.1 - 3.3e-50 170.5 0.0 7.5e-50 169.3 0.0 1.6 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 PVD22813.1 - 1.5e-12 47.7 0.1 3.1e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD22813.1 - 3.3e-09 36.5 0.1 7.7e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD22813.1 - 4.3e-07 29.7 0.0 8.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CENP-F_leu_zip PF10473.9 PVD22813.1 - 0.021 14.8 0.8 0.06 13.4 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Patched PF02460.18 PVD22814.1 - 9.1e-53 179.5 21.9 1e-52 179.3 21.9 1.0 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 PVD22814.1 - 0.076 10.7 18.9 0.092 10.4 18.9 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pex24p PF06398.11 PVD22814.1 - 3.6 6.5 7.5 5.5 5.9 3.7 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Patched PF02460.18 PVD22815.1 - 3.2e-18 65.3 0.2 4.1e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD22815.1 - 2.6e-15 56.6 0.0 3.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 PVD22816.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD22816.1 - 5.5e-06 26.3 5.1 5.5e-06 26.3 5.1 1.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Pkinase_Tyr PF07714.17 PVD22817.1 - 1.5e-87 293.2 0.0 2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD22817.1 - 1.7e-44 152.1 0.0 2.4e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PVD22817.1 - 0.0011 17.8 0.1 0.0025 16.7 0.1 1.4 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PVD22817.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4366 PF14283.6 PVD22817.1 - 0.14 12.2 0.1 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) MORN PF02493.20 PVD22818.1 - 5.9e-42 139.1 51.9 3.1e-09 36.2 0.7 8.7 9 0 0 9 9 9 8 MORN repeat Tropomyosin_1 PF12718.7 PVD22819.1 - 0.00036 20.7 37.4 0.0021 18.2 8.1 3.6 1 1 2 3 3 3 1 Tropomyosin like Fez1 PF06818.15 PVD22819.1 - 0.0037 17.7 19.3 0.0037 17.7 19.3 3.0 1 1 2 3 3 3 1 Fez1 FemAB PF02388.16 PVD22819.1 - 0.0041 16.0 4.8 0.0041 16.0 4.8 2.3 1 1 1 2 2 2 1 FemAB family DUF1664 PF07889.12 PVD22819.1 - 0.006 16.6 29.8 0.053 13.6 1.0 4.4 3 1 2 5 5 4 2 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 PVD22819.1 - 0.0077 16.4 2.9 0.0077 16.4 2.9 2.4 1 1 1 2 2 2 1 Cobalamin adenosyltransferase UPF0242 PF06785.11 PVD22819.1 - 0.016 15.3 33.9 0.017 15.2 22.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 PVD22819.1 - 0.021 15.4 29.4 0.77 10.4 4.8 4.7 1 1 3 4 4 4 0 SlyX DivIC PF04977.15 PVD22819.1 - 0.024 14.4 4.3 0.024 14.4 4.3 5.2 2 1 3 5 5 5 0 Septum formation initiator DUF948 PF06103.11 PVD22819.1 - 0.039 14.2 12.0 0.11 12.8 2.5 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 PVD22819.1 - 0.04 14.0 2.1 0.04 14.0 2.1 5.4 3 3 3 6 6 5 0 bZIP transcription factor AAA_13 PF13166.6 PVD22819.1 - 0.043 12.5 28.0 0.056 12.1 12.4 2.1 1 1 1 2 2 2 0 AAA domain KASH_CCD PF14662.6 PVD22819.1 - 0.096 12.5 39.4 0.11 12.4 28.4 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 PVD22819.1 - 0.11 12.3 36.5 0.061 13.1 21.6 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HAP1_N PF04849.13 PVD22819.1 - 0.12 11.5 36.9 0.2 10.8 18.5 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region T6PP_N PF18572.1 PVD22819.1 - 0.14 12.0 15.1 0.28 11.0 7.9 2.8 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain GAS PF13851.6 PVD22819.1 - 0.15 11.4 39.6 0.61 9.4 15.7 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.11 PVD22819.1 - 0.15 11.8 19.6 3.4 7.5 3.2 3.7 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.21 PVD22819.1 - 0.16 11.6 34.0 4.2 6.8 22.4 3.3 1 1 2 3 3 3 0 Intermediate filament protein DASH_Dad1 PF08649.10 PVD22819.1 - 0.16 12.2 3.6 1.2 9.4 0.3 3.8 4 1 0 4 4 3 0 DASH complex subunit Dad1 BLOC1_2 PF10046.9 PVD22819.1 - 0.16 12.3 27.9 3.9 7.8 1.2 4.5 2 1 3 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Macoilin PF09726.9 PVD22819.1 - 0.17 10.4 23.7 0.21 10.1 23.7 1.2 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 PVD22819.1 - 0.25 10.2 36.8 0.1 11.5 12.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein FliJ PF02050.16 PVD22819.1 - 0.37 11.0 32.8 0.52 10.6 14.1 3.3 1 1 1 2 2 2 0 Flagellar FliJ protein NPV_P10 PF05531.12 PVD22819.1 - 0.48 10.9 18.2 5.7 7.5 4.3 4.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 PVD22819.1 - 0.49 8.5 30.2 0.075 11.2 20.9 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HOOK PF05622.12 PVD22819.1 - 0.68 8.0 36.8 0.0057 14.9 15.7 2.1 1 1 1 2 2 2 0 HOOK protein MctB PF11382.8 PVD22819.1 - 0.7 9.6 7.4 3.1 7.4 0.2 2.7 2 1 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF4407 PF14362.6 PVD22819.1 - 0.73 9.1 21.6 3.9 6.8 21.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 PVD22819.1 - 0.74 7.7 24.4 0.045 11.7 11.7 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 PVD22819.1 - 0.76 10.3 30.3 1.9 9.0 4.7 3.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF3450 PF11932.8 PVD22819.1 - 0.82 8.9 30.9 0.66 9.2 11.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 PVD22819.1 - 0.84 10.0 35.6 0.14 12.5 4.7 4.9 2 1 3 5 5 4 0 Csm1 N-terminal domain ATG16 PF08614.11 PVD22819.1 - 0.86 9.8 39.6 0.042 14.1 18.3 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 PVD22819.1 - 0.94 10.1 32.1 2.5 8.8 10.3 4.3 1 1 5 6 6 6 0 Initiation control protein YabA LPP PF04728.13 PVD22819.1 - 0.97 9.9 17.0 0.56 10.6 0.3 4.3 4 1 1 5 5 3 0 Lipoprotein leucine-zipper Lebercilin PF15619.6 PVD22819.1 - 1.1 8.9 37.3 0.13 11.9 12.6 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 PVD22819.1 - 1.1 8.9 37.4 0.057 13.2 25.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3584 PF12128.8 PVD22819.1 - 1.3 6.5 32.7 3.7 4.9 32.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 PVD22819.1 - 1.4 8.9 14.4 0.94 9.5 2.5 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4446 PF14584.6 PVD22819.1 - 1.5 8.8 23.1 1.7 8.6 3.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Prefoldin_3 PF13758.6 PVD22819.1 - 1.6 8.8 19.6 2.2 8.4 0.2 3.6 3 1 0 3 3 2 0 Prefoldin subunit DUF4709 PF15821.5 PVD22819.1 - 1.6 9.0 24.9 0.14 12.5 6.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) DUF641 PF04859.12 PVD22819.1 - 1.7 8.9 32.7 0.26 11.6 2.8 4.2 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) MAAL_C PF07476.11 PVD22819.1 - 1.8 7.7 9.2 0.54 9.4 3.4 2.1 1 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DUF4988 PF16378.5 PVD22819.1 - 2.2 7.9 9.5 10 5.7 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function FAM76 PF16046.5 PVD22819.1 - 2.3 7.5 31.7 1.2 8.4 12.4 2.2 1 1 1 2 2 2 0 FAM76 protein DUF4874 PF16173.5 PVD22819.1 - 2.4 7.8 9.9 0.35 10.5 5.2 2.0 3 0 0 3 3 1 0 Domain of unknown function (DUF4874) DUF2203 PF09969.9 PVD22819.1 - 2.9 8.6 21.5 4.9 7.9 6.5 3.4 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF745 PF05335.13 PVD22819.1 - 3 7.5 24.0 2 8.1 17.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Prefoldin PF02996.17 PVD22819.1 - 3.1 7.7 23.0 1.7 8.5 4.4 4.3 1 1 1 4 4 4 0 Prefoldin subunit TSC22 PF01166.18 PVD22819.1 - 3.5 8.0 25.9 2.3 8.6 0.4 4.7 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF2730 PF10805.8 PVD22819.1 - 3.6 7.7 16.6 0.16 12.1 4.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) HMMR_N PF15905.5 PVD22819.1 - 3.7 6.9 40.1 47 3.3 37.8 2.3 2 1 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 PVD22819.1 - 3.7 6.6 30.6 1.2 8.1 22.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc29 PF17082.5 PVD22819.1 - 3.9 7.2 22.8 0.36 10.6 4.5 3.5 1 1 2 3 3 3 0 Spindle Pole Component 29 Thioesterase PF00975.20 PVD22819.1 - 4.5 7.3 7.8 4.1 7.5 6.5 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF812 PF05667.11 PVD22819.1 - 4.7 6.0 34.8 9.5 5.0 34.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Vps51 PF08700.11 PVD22819.1 - 4.7 7.4 21.5 3.4 7.8 5.3 4.4 3 1 1 4 4 4 0 Vps51/Vps67 DASH_Hsk3 PF08227.11 PVD22819.1 - 5.2 7.5 7.8 0.43 11.0 0.2 3.1 3 0 0 3 3 1 0 DASH complex subunit Hsk3 like PKcGMP_CC PF16808.5 PVD22819.1 - 5.2 7.0 11.3 1.1 9.2 1.1 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Cauli_DNA-bind PF03310.13 PVD22819.1 - 5.3 7.1 11.3 0.36 10.9 3.3 2.9 1 1 1 3 3 2 0 Caulimovirus DNA-binding protein MAD PF05557.13 PVD22819.1 - 5.3 5.3 38.0 29 2.9 17.2 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein FapA PF03961.13 PVD22819.1 - 5.5 5.5 29.5 3.8 6.0 14.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A RPW8 PF05659.11 PVD22819.1 - 6.3 6.5 17.5 2 8.1 5.9 3.6 2 2 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 PVD22819.1 - 6.3 5.9 26.2 0.081 12.2 13.3 2.8 1 1 2 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.10 PVD22819.1 - 6.5 6.9 34.8 0.23 11.7 10.2 3.4 2 1 2 4 4 3 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.6 PVD22819.1 - 7.1 6.0 32.3 0.73 9.2 4.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) TMF_DNA_bd PF12329.8 PVD22819.1 - 7.3 6.7 39.9 6.7 6.8 12.8 4.7 1 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding Sec34 PF04136.15 PVD22819.1 - 7.5 6.4 20.0 2 8.3 10.3 3.3 1 1 2 3 3 3 0 Sec34-like family CorA PF01544.18 PVD22819.1 - 7.8 5.7 22.9 6.3 6.0 4.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4094 PF13334.6 PVD22819.1 - 8.2 6.9 16.4 1.8e+04 -4.3 16.2 3.0 1 1 0 1 1 0 0 Domain of unknown function (DUF4094) MCPsignal PF00015.21 PVD22819.1 - 8.3 6.2 11.8 2.1 8.1 0.6 2.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CSN5_C PF18323.1 PVD22819.1 - 8.6 7.4 16.7 0.26 12.2 1.7 2.9 3 1 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain Exonuc_VII_L PF02601.15 PVD22819.1 - 9.5 5.7 30.0 3.8 7.0 15.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 PVD22819.1 - 10 6.8 22.0 15 6.3 4.4 3.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal G-patch_2 PF12656.7 PVD22820.1 - 2.5e-22 78.7 0.2 8.1e-22 77.1 0.2 1.9 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 PVD22820.1 - 2.3e-10 40.2 1.2 4.3e-10 39.3 1.2 1.5 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 PVD22820.1 - 4.2e-09 36.1 3.9 2.2e-06 27.4 2.2 2.8 2 0 0 2 2 2 2 KOW motif KN17_SH3 PF18131.1 PVD22820.1 - 1.1e-07 31.9 1.7 6.2e-06 26.2 0.2 2.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain Ran_BP1 PF00638.18 PVD22821.1 - 2.8e-16 59.9 0.0 5.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 PVD22821.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 WH1 domain FGGY_C PF02782.16 PVD22822.1 - 1.4e-48 165.2 0.1 2e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 PVD22822.1 - 2.5e-27 96.0 0.0 3.9e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Thymidylat_synt PF00303.19 PVD22822.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Thymidylate synthase BcrAD_BadFG PF01869.20 PVD22822.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Nop14 PF04147.12 PVD22823.1 - 0.075 11.3 3.8 0.1 10.8 3.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4376 PF14301.6 PVD22823.1 - 0.093 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) CPSF100_C PF13299.6 PVD22823.1 - 0.66 10.1 5.5 2.5 8.3 1.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Myc_N PF01056.18 PVD22823.1 - 1.3 8.9 10.0 0.083 12.8 4.6 1.8 2 0 0 2 2 2 0 Myc amino-terminal region DNA_pol_phi PF04931.13 PVD22823.1 - 4.4 5.3 11.0 6.2 4.8 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Radical_SAM PF04055.21 PVD22824.1 - 1.2e-06 29.0 0.6 4.3e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Radical_SAM_C PF16199.5 PVD22824.1 - 7e-05 22.8 0.0 0.00063 19.7 0.0 2.3 2 0 0 2 2 2 1 Radical_SAM C-terminal domain PP2C_C PF07830.13 PVD22824.1 - 0.038 14.4 0.2 0.081 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain LRR_6 PF13516.6 PVD22825.1 - 2.1e-19 67.9 21.1 0.019 15.0 0.1 8.1 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 PVD22825.1 - 2.9e-09 36.2 3.1 32 5.6 0.0 7.9 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 PVD22825.1 - 7e-06 26.3 17.2 0.12 12.8 1.1 5.8 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) EF-hand_1 PF00036.32 PVD22825.1 - 0.0011 18.4 0.8 0.004 16.6 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PVD22825.1 - 0.025 14.5 0.1 0.18 11.8 0.1 2.6 1 0 0 1 1 1 0 EF-hand domain Meis_PKNOX_N PF16493.5 PVD22825.1 - 0.027 14.8 0.0 0.34 11.3 0.0 2.6 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 EF-hand_8 PF13833.6 PVD22825.1 - 0.095 12.6 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair LRR_8 PF13855.6 PVD22825.1 - 0.16 11.7 20.4 4.9 7.0 4.3 6.3 5 1 1 6 6 6 0 Leucine rich repeat DUF223 PF02721.14 PVD22826.1 - 0.04 14.2 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF223 7tm_1 PF00001.21 PVD22827.1 - 6.8e-34 117.4 4.7 1e-33 116.8 4.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD22827.1 - 2.6e-05 24.0 14.2 4.2e-05 23.3 14.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD22827.1 - 8.1e-05 22.5 10.5 0.00011 22.1 10.5 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD22827.1 - 0.0012 18.2 12.2 0.0019 17.6 12.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 PVD22827.1 - 0.12 12.4 5.9 0.1 12.6 1.0 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TMEM154 PF15102.6 PVD22827.1 - 9.6 6.1 9.5 4.4 7.2 0.0 3.2 4 0 0 4 4 4 0 TMEM154 protein family NACHT PF05729.12 PVD22829.1 - 9.8e-10 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 PVD22829.1 - 2.2e-06 28.0 0.0 5.1e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD22829.1 - 6e-06 26.7 0.0 3.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF4062 PF13271.6 PVD22829.1 - 0.006 16.9 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) Viral_helicase1 PF01443.18 PVD22829.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APAF1_C PF17908.1 PVD22829.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 APAF-1 helical domain AAA_30 PF13604.6 PVD22829.1 - 0.17 11.5 0.0 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain CUB PF00431.20 PVD22830.1 - 2.7e-28 98.5 0.0 2.7e-12 47.0 0.0 3.8 3 0 0 3 3 3 3 CUB domain MAP17 PF15807.5 PVD22830.1 - 0.00046 20.4 0.0 0.00046 20.4 0.0 3.1 4 0 0 4 4 4 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FeoB_associated PF12669.7 PVD22830.1 - 0.42 11.0 2.8 0.89 10.0 2.8 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Piezo_RRas_bdg PF12166.8 PVD22830.1 - 2 7.6 5.6 8.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain CBM_1 PF00734.18 PVD22831.1 - 4.7 7.3 8.1 9.4 6.3 0.2 3.0 3 0 0 3 3 3 0 Fungal cellulose binding domain ArfGap PF01412.18 PVD22833.1 - 1.4e-33 115.4 0.5 1.7e-33 115.1 0.5 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_L37ae PF01780.19 PVD22833.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L37ae protein family HEAT_2 PF13646.6 PVD22834.1 - 6.9e-07 29.6 0.1 0.11 12.9 0.0 3.4 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 PVD22834.1 - 0.039 14.2 1.5 16 6.0 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat CFC PF09443.10 PVD22835.1 - 1.7e-09 37.4 9.7 1.7e-09 37.4 9.7 2.3 2 1 0 2 2 2 1 Cripto_Frl-1_Cryptic (CFC) Pacifastin_I PF05375.13 PVD22835.1 - 0.0025 17.5 2.8 0.0074 16.0 2.8 1.9 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Surp PF01805.20 PVD22836.1 - 1.6e-15 56.8 0.5 4.2e-15 55.5 0.5 1.7 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 PVD22836.1 - 3.2e-15 56.7 0.4 1.2e-14 54.8 0.5 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. G-patch PF01585.23 PVD22836.1 - 7.3e-13 48.2 0.8 1.4e-12 47.3 0.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD22836.1 - 0.15 12.2 0.5 0.4 10.8 0.5 1.8 1 0 0 1 1 1 0 G-patch domain NPV_P10 PF05531.12 PVD22836.1 - 7.4 7.1 12.4 0.97 9.9 3.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 PVD22837.1 - 1.1e-65 221.6 0.0 1.9e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22837.1 - 4.3e-30 104.9 0.0 6.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD22837.1 - 2e-06 26.9 0.1 0.00011 21.1 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Kdo PF06293.14 PVD22837.1 - 6.5e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RRN7 PF11781.8 PVD22837.1 - 0.00075 19.1 0.2 0.0021 17.7 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Kinase-like PF14531.6 PVD22837.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 PVD22837.1 - 0.023 14.6 0.0 0.085 12.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD22837.1 - 0.03 13.3 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain rRNA_proc-arch PF13234.6 PVD22838.1 - 6.8e-88 295.1 0.1 1.2e-87 294.3 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 PVD22838.1 - 3.8e-53 179.5 0.3 1e-52 178.1 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PVD22838.1 - 6.2e-18 65.2 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD22838.1 - 1.5e-06 28.6 0.0 8.8e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD22838.1 - 0.00046 20.2 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PVD22838.1 - 0.032 14.5 0.0 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Thioredoxin_7 PF13899.6 PVD22839.1 - 8.8e-17 61.1 0.1 1.9e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 PVD22839.1 - 1.1e-07 31.8 0.1 1.8e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 PVD22839.1 - 3.4e-05 23.9 0.1 5.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.6 PVD22839.1 - 9.6e-05 22.2 0.1 0.00021 21.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 PVD22839.1 - 0.00041 20.8 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PVD22839.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PVD22839.1 - 0.0029 17.3 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PVD22839.1 - 0.02 15.2 0.1 0.074 13.4 0.1 2.1 2 1 0 2 2 2 0 Thioredoxin-like zf-3CxxC PF13695.6 PVD22839.1 - 0.12 12.9 0.4 0.2 12.2 0.4 1.4 1 1 0 1 1 1 0 Zinc-binding domain Tctex-1 PF03645.13 PVD22840.1 - 6.3e-24 84.2 0.1 9.1e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF1647 PF07801.11 PVD22841.1 - 2.3e-06 27.4 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Pes-10 PF07149.11 PVD22841.1 - 0.037 13.1 7.7 0.052 12.6 7.7 1.2 1 0 0 1 1 1 0 Pes-10 PX PF00787.24 PVD22841.1 - 0.076 13.0 0.2 12 5.9 0.0 2.5 2 1 0 2 2 2 0 PX domain DDHD PF02862.17 PVD22841.1 - 0.087 13.0 0.9 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 DDHD domain RXT2_N PF08595.11 PVD22841.1 - 0.29 11.2 4.7 0.63 10.1 4.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 PVD22841.1 - 0.51 10.0 4.0 0.99 9.1 4.0 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 PVD22841.1 - 0.75 8.0 5.5 1.1 7.4 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 PVD22841.1 - 4.4 6.9 19.1 1.2 8.8 8.7 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FYDLN_acid PF09538.10 PVD22841.1 - 7.6 7.3 14.5 4.6 8.0 12.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 PVD22841.1 - 9.5 6.1 13.8 14 5.5 9.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Syntaxin_2 PF14523.6 PVD22842.1 - 7.8e-30 103.2 14.1 2.4e-29 101.7 8.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 PVD22842.1 - 2.4e-18 65.8 3.3 3e-18 65.6 0.6 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PVD22842.1 - 5.2e-12 45.9 11.7 5.2e-12 45.9 11.7 1.7 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 PVD22842.1 - 0.00075 19.2 10.5 0.0013 18.5 1.2 2.5 2 1 0 2 2 2 1 Synaptobrevin DUF2207 PF09972.9 PVD22842.1 - 0.031 13.0 0.3 0.063 12.0 0.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5345 PF17280.2 PVD22842.1 - 0.062 13.3 1.2 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3671 PF12420.8 PVD22842.1 - 0.069 13.2 0.2 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF4988 PF16378.5 PVD22842.1 - 0.089 12.4 2.6 0.1 12.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF3040 PF11239.8 PVD22842.1 - 0.22 11.8 1.4 0.4 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Sulfatase_C PF14707.6 PVD22842.1 - 1.2 9.9 4.1 0.89 10.3 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF883 PF05957.13 PVD22842.1 - 1.4 9.5 8.7 0.35 11.5 1.1 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 PVD22842.1 - 1.4 6.7 10.7 0.068 11.1 2.6 2.0 1 1 1 2 2 2 0 Prominin CCDC-167 PF15188.6 PVD22842.1 - 4 7.8 11.2 5.6 7.4 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Orf78 PF06024.12 PVD22842.1 - 4.1 7.7 6.3 0.43 10.9 0.3 2.3 2 1 0 2 2 2 0 Orf78 (ac78) ING PF12998.7 PVD22842.1 - 4.1 8.0 7.6 4 8.1 0.6 2.8 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-C4H2 PF10146.9 PVD22842.1 - 6.6 7.0 17.5 6.3 7.0 5.0 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein TMCO5 PF14992.6 PVD22842.1 - 8.3 5.9 14.7 1.9 8.0 2.0 2.3 1 1 1 2 2 2 0 TMCO5 family zf-H2C2_5 PF13909.6 PVD22843.1 - 7.5e-05 22.4 32.3 0.00087 19.0 1.5 4.5 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 PVD22843.1 - 0.99 9.1 18.1 7.2 6.3 2.6 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 PVD22843.1 - 2.7 8.5 8.1 5.1 7.6 0.5 3.6 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Cys_rich_KTR PF14205.6 PVD22843.1 - 4.3 7.2 5.7 10 6.0 0.3 3.1 2 1 1 3 3 3 0 Cysteine-rich KTR Glyco_transf_18 PF15024.6 PVD22844.1 - 0.012 14.2 0.3 0.014 14.0 0.3 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 18 BORCS6 PF10157.9 PVD22844.1 - 0.036 14.3 0.5 0.045 14.0 0.5 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF1948 PF09185.10 PVD22844.1 - 0.075 12.9 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) PSK_trans_fac PF07704.11 PVD22844.1 - 0.71 10.7 5.7 1.4 9.7 3.8 2.2 1 1 1 2 2 2 0 Rv0623-like transcription factor TFIIA PF03153.13 PVD22844.1 - 1.7 8.5 9.1 1.9 8.4 9.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPICE PF15678.5 PVD22845.1 - 1.8e-63 215.3 21.8 8.1e-63 213.2 19.4 2.4 1 1 0 1 1 1 1 Centriole duplication and mitotic chromosome congression SHE3 PF17078.5 PVD22845.1 - 0.0095 15.7 2.5 0.0095 15.7 2.5 3.2 3 1 0 3 3 3 1 SWI5-dependent HO expression protein 3 DUF948 PF06103.11 PVD22845.1 - 0.095 13.0 2.8 7.1 7.0 0.2 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1192 PF06698.11 PVD22845.1 - 0.41 10.7 3.7 1.1 9.4 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) SNF2_N PF00176.23 PVD22846.1 - 5.3e-74 249.0 2.1 5.3e-74 249.0 2.1 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD22846.1 - 5.7e-20 71.7 0.3 2.9e-19 69.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 PVD22846.1 - 1.2e-19 70.1 0.5 1.1e-18 67.0 0.4 2.4 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.6 PVD22846.1 - 1e-18 67.7 9.2 1e-18 67.7 9.2 4.9 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 PVD22846.1 - 2.4e-18 66.2 6.4 2.4e-18 66.2 6.4 4.2 4 0 0 4 4 4 1 HSA QLQ PF08880.11 PVD22846.1 - 3.7e-13 49.0 1.0 1.2e-12 47.3 1.0 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 PVD22846.1 - 6.6e-11 42.5 0.0 6.6e-11 42.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DBINO PF13892.6 PVD22846.1 - 0.00064 20.1 12.6 0.00064 20.1 12.6 4.3 3 1 0 3 3 3 1 DNA-binding domain BRK PF07533.16 PVD22846.1 - 0.036 13.7 0.0 0.096 12.3 0.0 1.8 1 0 0 1 1 1 0 BRK domain DUF3246 PF11596.8 PVD22846.1 - 4.7 6.6 14.5 0.48 9.8 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Brix PF04427.18 PVD22847.1 - 4.1e-29 102.1 0.1 5.2e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF3198 PF11433.8 PVD22847.1 - 0.093 12.6 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) PAM2 PF07145.15 PVD22848.1 - 2.5e-06 26.8 3.2 0.021 14.5 0.7 3.1 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MIF4G PF02854.19 PVD22848.1 - 0.0027 17.4 0.9 1.2 8.7 0.1 2.4 1 1 1 2 2 2 2 MIF4G domain Acetyltransf_1 PF00583.25 PVD22849.1 - 3.6e-08 33.6 0.0 1.2e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD22849.1 - 1.1e-07 31.8 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD22849.1 - 1.6e-07 31.7 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PVD22849.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 PVD22849.1 - 0.0031 17.1 0.0 0.0082 15.7 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 PVD22849.1 - 0.0044 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein A2M PF00207.22 PVD22849.1 - 0.08 12.8 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Linker_histone PF00538.19 PVD22850.1 - 1.1e-28 99.4 1.5 1.1e-28 99.4 1.5 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family Pkinase_Tyr PF07714.17 PVD22851.1 - 1.7e-14 53.8 0.0 6e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD22851.1 - 2.8e-13 49.9 0.1 2.7e-05 23.7 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain PRESAN PF09687.10 PVD22851.1 - 0.12 13.0 2.1 0.35 11.4 2.1 1.7 1 0 0 1 1 1 0 Plasmodium RESA N-terminal OSR1_C PF12202.8 PVD22851.1 - 0.36 11.1 2.0 0.77 10.0 0.0 2.6 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C-terminal domain PP2C PF00481.21 PVD22852.1 - 2.2e-73 247.1 4.5 1.7e-58 198.3 0.2 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 PVD22852.1 - 1.7e-05 24.6 0.0 0.0022 17.7 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C Ecm29 PF13001.7 PVD22853.1 - 1.2e-145 486.0 2.9 1.2e-145 486.0 2.9 3.7 5 0 0 5 5 5 1 Proteasome stabiliser HEAT PF02985.22 PVD22853.1 - 6.2e-18 63.4 14.2 0.0092 16.2 0.0 13.7 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.6 PVD22853.1 - 7.9e-14 51.8 23.1 0.0029 18.1 0.0 12.8 12 2 2 14 14 14 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PVD22853.1 - 1.9e-10 41.2 1.0 0.14 12.8 0.0 7.4 7 1 1 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 PVD22853.1 - 8.8e-10 38.8 15.2 0.055 13.9 0.0 10.5 10 3 2 12 12 12 2 HEAT repeats Cnd1 PF12717.7 PVD22853.1 - 4.7e-06 26.7 11.0 0.026 14.6 0.0 6.3 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PVD22853.1 - 4.9e-05 22.1 19.2 0.011 14.3 0.0 6.5 6 0 0 6 6 6 3 Adaptin N terminal region CLASP_N PF12348.8 PVD22853.1 - 0.0046 16.5 11.2 7.5 6.0 0.0 6.8 7 0 0 7 7 7 2 CLASP N terminal LON_substr_bdg PF02190.16 PVD22853.1 - 0.027 14.3 0.1 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain MOR2-PAG1_C PF14225.6 PVD22853.1 - 0.21 11.4 2.7 0.57 10.0 0.1 3.1 2 1 0 2 2 2 0 Cell morphogenesis C-terminal BRCT PF00533.26 PVD22854.1 - 0.015 15.6 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AAA_lid_11 PF18198.1 PVD22854.1 - 0.18 11.6 0.0 0.48 10.2 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain 7tm_1 PF00001.21 PVD22855.1 - 2.1e-48 165.0 11.9 2.6e-48 164.6 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD22855.1 - 2.5e-05 23.7 0.4 2.5e-05 23.7 0.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD22855.1 - 0.00033 20.4 11.2 0.00033 20.4 11.2 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx WD40 PF00400.32 PVD22857.1 - 3.7e-12 46.5 9.7 0.008 17.0 1.8 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box PF00646.33 PVD22857.1 - 5.2e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PVD22857.1 - 0.00012 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2345 PF10106.9 PVD22857.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) F-box_4 PF15966.5 PVD22857.1 - 0.02 14.8 0.5 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 F-box PQQ_3 PF13570.6 PVD22857.1 - 0.083 13.4 0.1 57 4.4 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain DUF4224 PF13986.6 PVD22859.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) BTB_2 PF02214.22 PVD22863.1 - 4.5e-32 110.3 0.0 7e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PVD22863.1 - 0.042 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Ion_trans PF00520.31 PVD22866.1 - 7.3e-40 136.7 2.5 5.4e-31 107.7 0.1 2.1 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 PVD22866.1 - 4.6e-13 48.9 1.5 4.6e-13 48.9 1.5 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 PVD22866.1 - 0.0014 17.4 0.3 0.0022 16.8 0.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Period_C PF12114.8 PVD22866.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Cytochrom_B_C PF00032.17 PVD22866.1 - 0.22 11.8 1.5 0.22 11.8 0.1 1.7 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Fungus-induced PF10917.8 PVD22867.1 - 1.5 9.2 3.2 1.7 9.0 0.1 2.5 2 0 0 2 2 2 0 Fungus-induced protein Hid1 PF12722.7 PVD22868.1 - 2.4 6.2 6.3 3.9 5.5 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 PVD22868.1 - 4.9 5.9 11.9 7.8 5.2 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.9 PVD22868.1 - 8.6 4.5 15.1 12 4.0 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UQ_con PF00179.26 PVD22869.1 - 6.8e-36 123.0 0.1 9.1e-36 122.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ricin_B_lectin PF00652.22 PVD22869.1 - 0.014 15.6 0.5 0.21 11.8 0.3 2.3 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain UEV PF05743.13 PVD22869.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Inositol_P PF00459.25 PVD22870.1 - 1.5e-42 146.0 0.1 1.8e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pdase_C33_assoc PF14756.6 PVD22871.1 - 0.058 13.3 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C33-associated domain 7tm_1 PF00001.21 PVD22872.1 - 8.6e-41 140.0 14.8 1.2e-40 139.6 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD22872.1 - 9.7e-08 31.6 13.2 0.0007 19.0 0.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD22872.1 - 4.6e-05 23.2 9.9 4.6e-05 23.2 9.9 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ocular_alb PF02101.15 PVD22872.1 - 0.00041 19.4 0.0 0.00041 19.4 0.0 2.1 2 0 0 2 2 2 1 Ocular albinism type 1 protein DUF3995 PF13160.6 PVD22872.1 - 0.035 14.5 8.5 0.12 12.8 2.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) 7tm_1 PF00001.21 PVD22873.1 - 1.2e-09 37.9 0.3 1.8e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2417 PF10329.9 PVD22873.1 - 0.92 8.9 4.2 1.2 8.5 3.9 1.3 1 1 0 1 1 1 0 Region of unknown function (DUF2417) 7tm_1 PF00001.21 PVD22874.1 - 2.2e-12 46.9 0.2 2.4e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD22875.1 - 3.4e-45 154.4 0.9 1.7e-24 86.6 0.0 3.2 3 0 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD22875.1 - 0.00031 20.2 4.5 0.091 12.1 0.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD22875.1 - 0.021 14.6 0.2 0.021 14.6 0.2 2.1 3 0 0 3 3 3 0 Olfactory receptor WD40_alt PF14077.6 PVD22875.1 - 0.13 12.2 1.0 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif 7tm_1 PF00001.21 PVD22876.1 - 1e-29 103.7 2.2 6.2e-29 101.1 2.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD22876.1 - 0.0001 21.8 3.0 0.0001 21.8 3.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 PVD22876.1 - 0.0017 17.8 0.7 0.0017 17.8 0.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 PVD22876.1 - 0.0075 15.9 6.3 0.0075 15.9 6.3 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2729 PF10870.8 PVD22876.1 - 0.087 12.7 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DNA_pol3_chi PF04364.13 PVD22877.1 - 0.027 14.6 0.2 0.032 14.4 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC NHL PF01436.21 PVD22882.1 - 8.5e-09 35.0 10.3 0.053 13.6 0.0 5.2 4 1 0 4 4 4 3 NHL repeat DprA_WH PF17782.1 PVD22882.1 - 0.061 13.4 0.7 0.061 13.4 0.7 1.8 2 0 0 2 2 2 0 DprA winged helix domain SMC_Nse1 PF07574.13 PVD22883.1 - 1.1e-25 90.7 1.2 4.2e-24 85.5 1.2 2.3 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Reprolysin_5 PF13688.6 PVD22883.1 - 5.4e-10 39.7 0.3 1.8e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 PVD22883.1 - 4.1e-09 36.8 4.7 4.1e-09 36.8 4.7 2.7 3 0 0 3 3 1 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 PVD22883.1 - 2e-08 34.3 0.9 4.1e-08 33.3 0.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD22883.1 - 2.6e-06 27.2 0.3 5.2e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like zf-RING-like PF08746.11 PVD22883.1 - 2.9e-06 27.5 13.6 2.9e-06 27.5 13.6 2.4 2 0 0 2 2 2 1 RING-like domain Reprolysin_3 PF13582.6 PVD22883.1 - 1.5e-05 25.5 0.0 4.5e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD22883.1 - 0.0037 17.1 1.3 0.01 15.7 0.2 2.2 2 1 0 2 2 2 1 Matrixin DUF327 PF03885.13 PVD22883.1 - 0.16 11.9 0.2 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Zn_ribbon_17 PF17120.5 PVD22883.1 - 0.55 9.9 11.4 1.5 8.5 11.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 PVD22883.1 - 1.5 8.7 15.8 0.098 12.6 10.0 2.0 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.29 PVD22884.1 - 3.7e-41 140.8 2.3 3.8e-41 140.8 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD22884.1 - 2.3e-28 98.7 0.0 2.3e-28 98.7 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PVD22884.1 - 0.0053 17.0 4.5 0.0055 17.0 0.1 3.1 3 1 1 4 4 4 1 AAA domain Stm1_N PF09598.10 PVD22884.1 - 7.3 7.5 8.2 1.9 9.4 0.1 2.7 2 0 0 2 2 2 0 Stm1 EF-hand_2 PF09068.11 PVD22885.1 - 8e-36 122.9 0.4 2e-35 121.6 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 PVD22885.1 - 2.5e-23 82.3 0.0 8.4e-23 80.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand ZZ PF00569.17 PVD22885.1 - 4.4e-11 42.4 7.0 8.4e-11 41.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 PVD22885.1 - 0.0018 18.6 5.8 0.0035 17.6 5.8 1.5 1 0 0 1 1 1 1 C1 domain SOGA PF11365.8 PVD22885.1 - 0.013 16.6 5.2 0.073 14.2 3.9 2.8 2 0 0 2 2 2 0 Protein SOGA STAT_alpha PF01017.20 PVD22885.1 - 0.021 14.8 4.6 0.064 13.1 4.6 1.8 1 0 0 1 1 1 0 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.22 PVD22885.1 - 1.5 9.1 5.4 1 9.7 2.8 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MerR-DNA-bind PF09278.11 PVD22885.1 - 2.4 8.8 9.1 0.51 10.9 1.2 2.8 2 0 0 2 2 2 0 MerR, DNA binding YlqD PF11068.8 PVD22885.1 - 3.3 8.1 7.1 2.9 8.3 3.9 2.4 2 0 0 2 2 2 0 YlqD protein zf-RanBP PF00641.18 PVD22886.1 - 1.4e-23 81.9 31.7 4.3e-10 38.7 3.3 4.0 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others Nup153 PF08604.10 PVD22886.1 - 1.5e-23 83.4 21.6 2.7e-23 82.6 22.1 6.7 3 2 3 6 6 6 4 Nucleoporin Nup153-like zf-Sec23_Sec24 PF04810.15 PVD22886.1 - 3 8.0 6.3 24 5.1 0.1 3.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 PVD22886.1 - 6.2 6.3 17.3 0.3 10.5 0.7 3.5 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF5537 PF17690.1 PVD22887.1 - 5.7e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5537) SoxZ PF08770.11 PVD22888.1 - 0.00026 20.7 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Sulphur oxidation protein SoxZ Apolipoprotein PF01442.18 PVD22888.1 - 0.11 12.3 2.2 0.36 10.7 0.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 PVD22888.1 - 0.14 11.8 1.9 0.38 10.3 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF5627 PF18620.1 PVD22889.1 - 0.033 14.1 5.1 11 5.9 0.1 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5627) Big_3_5 PF16640.5 PVD22889.1 - 0.09 13.0 4.3 2.5 8.3 0.1 4.3 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) CBM_4_9 PF02018.17 PVD22889.1 - 0.73 10.1 11.5 7 6.9 1.1 4.9 3 2 2 5 5 5 0 Carbohydrate binding domain Big_4 PF07532.11 PVD22889.1 - 9.1 6.1 8.0 20 5.0 0.1 3.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) Vitellogenin_N PF01347.22 PVD22890.1 - 2.9e-74 250.6 0.0 2.1e-45 155.3 0.0 2.2 1 1 1 2 2 2 2 Lipoprotein amino terminal region DUF1943 PF09172.11 PVD22890.1 - 1.5e-61 208.3 1.5 1.6e-60 205.0 1.1 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 PVD22890.1 - 2.9e-14 53.4 0.2 1.9e-13 50.8 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1081) HEAT_2 PF13646.6 PVD22890.1 - 0.00022 21.6 0.3 0.0011 19.4 0.1 2.3 2 0 0 2 2 2 1 HEAT repeats Bactofilin PF04519.13 PVD22890.1 - 0.047 14.0 0.3 0.87 9.9 0.0 3.3 4 0 0 4 4 4 0 Polymer-forming cytoskeletal DUF1258 PF06869.12 PVD22890.1 - 0.095 12.2 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HEAT PF02985.22 PVD22890.1 - 0.54 10.7 2.4 27 5.4 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat DUF3522 PF12036.8 PVD22891.1 - 5.1e-46 157.3 13.5 6.8e-46 156.9 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) CitMHS PF03600.16 PVD22891.1 - 0.12 11.5 1.6 0.15 11.2 1.6 1.3 1 0 0 1 1 1 0 Citrate transporter EGF_2 PF07974.13 PVD22891.1 - 0.15 12.4 6.5 0.49 10.8 6.5 1.9 1 1 0 1 1 1 0 EGF-like domain BRCT_3 PF18428.1 PVD22891.1 - 0.16 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Per1 PF04080.13 PVD22891.1 - 0.37 10.5 10.3 0.53 10.0 10.3 1.2 1 0 0 1 1 1 0 Per1-like family NMN_transporter PF04973.12 PVD22891.1 - 1.4 8.9 8.4 1.5 8.8 7.0 1.7 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter MerC PF03203.14 PVD22891.1 - 6.2 7.3 12.0 0.28 11.7 4.0 2.6 1 1 2 3 3 3 0 MerC mercury resistance protein Rab_bind PF16704.5 PVD22892.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Rab binding domain Zn_Tnp_IS1 PF03811.13 PVD22892.1 - 0.045 13.5 0.2 0.073 12.8 0.2 1.3 1 0 0 1 1 1 0 InsA N-terminal domain Caskin-Pro-rich PF16907.5 PVD22893.1 - 1.9 9.1 14.1 2.1 8.9 2.6 3.6 3 0 0 3 3 3 0 Proline rich region of Caskin proteins PRIMA1 PF16101.5 PVD22893.1 - 5.8 7.0 12.0 13 5.9 0.4 3.6 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 MT PF12777.7 PVD22895.1 - 0.0011 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Transglut_core PF01841.19 PVD22895.1 - 0.0092 16.4 0.1 0.029 14.8 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily TRIC PF05197.13 PVD22896.1 - 5.4e-78 261.0 4.1 5.4e-78 261.0 4.1 1.4 2 0 0 2 2 2 1 TRIC channel EGF PF00008.27 PVD22897.1 - 9.4e-135 438.2 446.9 1.7e-07 31.4 7.9 30.1 29 1 0 29 29 29 29 EGF-like domain hEGF PF12661.7 PVD22897.1 - 1.4e-51 171.4 375.1 0.00022 21.7 8.8 31.8 29 1 0 29 29 29 23 Human growth factor-like EGF EGF_2 PF07974.13 PVD22897.1 - 1.5e-21 76.4 502.6 0.00035 20.9 10.6 29.7 29 0 0 29 29 29 22 EGF-like domain Ldl_recept_a PF00057.18 PVD22897.1 - 0.00014 22.0 4.9 0.00014 22.0 4.9 15.3 22 1 0 22 22 22 1 Low-density lipoprotein receptor domain class A EGF_3 PF12947.7 PVD22897.1 - 0.0024 18.0 4.4 0.0024 18.0 4.4 30.9 27 3 3 30 30 30 13 EGF domain Plasmod_Pvs28 PF06247.11 PVD22897.1 - 0.0066 16.7 7.0 0.0066 16.7 7.0 25.7 25 2 3 28 28 28 3 Pvs28 EGF domain Palm_thioest PF02089.15 PVD22899.1 - 1.7e-78 263.8 0.0 2.2e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase RNase_H PF00075.24 PVD22899.1 - 3e-27 95.6 0.0 5.7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 PVD22899.1 - 6.3e-06 26.4 0.2 1.5e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 PVD22899.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Ribosomal_S7e PF01251.18 PVD22900.1 - 4.2e-76 254.8 4.0 5.1e-76 254.5 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Peroxin-13_N PF04088.13 PVD22901.1 - 7.2e-44 149.6 0.3 9.9e-44 149.1 0.3 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 PVD22901.1 - 5e-11 42.3 0.0 1.2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22901.1 - 4.8e-09 35.7 0.0 1.1e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD22901.1 - 0.00058 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PLAT PF01477.23 PVD22902.1 - 8.3e-270 877.7 62.7 1e-20 74.4 0.0 20.9 21 1 0 21 21 21 20 PLAT/LH2 domain DCX PF03607.17 PVD22902.1 - 4.4e-25 87.6 0.0 1.8e-11 44.0 0.0 3.9 4 0 0 4 4 4 2 Doublecortin ATS3 PF06232.11 PVD22902.1 - 1.9e-15 56.8 0.0 1.2 9.0 0.0 10.7 11 0 0 11 11 11 5 Embryo-specific protein 3, (ATS3) FGF PF00167.18 PVD22902.1 - 0.024 14.7 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 0 Fibroblast growth factor DUF2914 PF11141.8 PVD22902.1 - 0.13 12.1 23.1 7.1 6.5 0.1 8.4 9 0 0 9 9 9 0 Protein of unknown function (DUF2914) hEGF PF12661.7 PVD22903.1 - 0.003 18.1 7.3 0.003 18.1 7.3 3.6 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_CA PF07645.15 PVD22903.1 - 0.011 15.9 4.8 0.011 15.9 4.8 3.6 2 1 1 3 3 3 0 Calcium-binding EGF domain EGF_3 PF12947.7 PVD22903.1 - 0.023 14.9 5.8 0.023 14.9 5.8 2.9 2 0 0 2 2 2 0 EGF domain EphA2_TM PF14575.6 PVD22903.1 - 0.12 13.3 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SEA PF01390.20 PVD22903.1 - 0.13 12.3 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 SEA domain cEGF PF12662.7 PVD22903.1 - 0.23 11.4 0.2 0.23 11.4 0.2 4.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like WD40 PF00400.32 PVD22904.1 - 2.6e-12 47.0 19.1 0.00025 21.8 0.2 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat ICAP-1_inte_bdg PF10480.9 PVD22904.1 - 2.6e-06 27.6 0.1 5.1e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Beta-1 integrin binding protein eIF2A PF08662.11 PVD22904.1 - 4e-05 23.6 2.3 0.047 13.6 0.2 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PVD22904.1 - 0.00098 19.4 1.3 0.095 13.0 0.5 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD22904.1 - 0.011 14.5 2.2 0.54 8.8 0.3 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TFIIS_M PF07500.14 PVD22905.1 - 2.7e-37 127.7 1.2 4.1e-37 127.1 1.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 PVD22905.1 - 1.3e-18 66.5 6.6 1.9e-18 66.0 5.2 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zf-CHY PF05495.12 PVD22905.1 - 0.16 12.5 3.6 0.31 11.5 3.6 1.5 1 0 0 1 1 1 0 CHY zinc finger C2 PF00168.30 PVD22906.1 - 4.4e-24 84.7 0.0 1.9e-12 47.3 0.1 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 PVD22906.1 - 3.9e-15 56.1 9.3 3.9e-15 56.1 9.3 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger PDZ_6 PF17820.1 PVD22906.1 - 2.6e-11 43.2 0.1 6.5e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD22906.1 - 8.6e-08 32.4 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD22906.1 - 2.2e-05 24.7 0.0 5.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain zf-piccolo PF05715.13 PVD22906.1 - 2.6e-05 24.3 6.7 6.7e-05 23.0 6.7 1.7 1 0 0 1 1 1 1 Piccolo Zn-finger PHD PF00628.29 PVD22906.1 - 6.7 6.7 6.8 15 5.5 6.8 1.7 1 0 0 1 1 1 0 PHD-finger zf-C2HE PF16278.5 PVD22907.1 - 3.5 8.1 6.9 1.1 9.7 0.5 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RWD PF05773.22 PVD22908.1 - 2.5e-22 79.4 0.0 4.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 PVD22908.1 - 9e-11 41.8 4.5 9e-11 41.8 4.5 3.5 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 PVD22908.1 - 0.0095 15.9 11.1 0.0095 15.9 11.1 3.2 2 2 1 3 3 3 1 zinc-RING finger domain CEBP_ZZ PF16366.5 PVD22908.1 - 0.074 13.3 17.0 0.064 13.5 4.0 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4 PF00097.25 PVD22908.1 - 4.1 7.4 25.8 0.066 13.1 8.2 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD22908.1 - 7.2 7.0 28.5 0.052 13.9 11.0 3.1 2 1 0 2 2 2 0 Ring finger domain GDC-P PF02347.16 PVD22909.1 - 6.2e-120 400.9 0.2 1.5e-98 330.5 0.0 3.4 3 1 1 4 4 4 3 Glycine cleavage system P-protein Aminotran_5 PF00266.19 PVD22909.1 - 0.0015 17.5 0.0 0.0036 16.3 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PVD22909.1 - 0.0023 17.3 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Nucleoporin_N PF08801.11 PVD22910.1 - 2.7e-104 349.3 0.0 3.1e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.8 PVD22910.1 - 0.04 12.6 0.1 0.37 9.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_C PF03177.14 PVD22911.1 - 1.1e-27 97.1 6.4 1.8e-27 96.3 6.4 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal ERAP1_C PF11838.8 PVD22911.1 - 0.46 10.0 5.1 0.24 10.9 0.5 2.5 2 1 0 2 2 2 0 ERAP1-like C-terminal domain Med30 PF11315.8 PVD22911.1 - 0.64 10.2 4.4 6.9 6.9 0.0 3.5 4 0 0 4 4 4 0 Mediator complex subunit 30 Arm PF00514.23 PVD22912.1 - 8.2e-06 25.7 0.1 0.012 15.7 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat WAPL PF07814.13 PVD22912.1 - 0.00078 18.3 0.9 0.0044 15.8 0.5 1.9 1 1 1 2 2 2 2 Wings apart-like protein regulation of heterochromatin Arm_2 PF04826.13 PVD22912.1 - 0.0061 16.1 0.2 0.19 11.2 0.0 2.0 1 1 1 2 2 2 2 Armadillo-like HEAT_2 PF13646.6 PVD22912.1 - 0.081 13.3 0.1 20 5.6 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats Pkinase PF00069.25 PVD22913.1 - 5.8e-76 255.3 0.0 8.8e-76 254.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22913.1 - 4e-43 147.6 0.0 5.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 PVD22913.1 - 1.1e-13 51.6 0.0 3.9e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 PVD22913.1 - 1.7e-08 34.2 0.0 9.6e-08 31.7 0.0 2.1 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 PVD22913.1 - 0.0002 21.0 0.2 0.00077 19.1 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PVD22913.1 - 0.051 13.5 0.2 0.23 11.4 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD22913.1 - 0.068 12.5 0.2 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 PVD22914.1 - 6.2e-51 173.4 43.1 1.5e-48 165.6 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD22914.1 - 3.2e-06 26.3 10.8 3.2e-06 26.3 10.8 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter ABC2_membrane_3 PF12698.7 PVD22915.1 - 1.4e-52 179.0 43.5 3.2e-35 121.9 9.3 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 PVD22915.1 - 6.1e-22 78.6 0.0 9.4e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PVD22915.1 - 7.8e-11 42.3 0.0 3.9e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PVD22915.1 - 1.9e-06 28.5 0.2 0.0096 16.6 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) cobW PF02492.19 PVD22916.1 - 1.1e-49 168.4 0.1 2.6e-49 167.2 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PVD22916.1 - 2.7e-19 68.9 0.2 1.5e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Ig_3 PF13927.6 PVD22916.1 - 6.1e-07 29.9 4.4 0.0069 17.0 0.1 3.1 4 0 0 4 4 2 2 Immunoglobulin domain ig PF00047.25 PVD22916.1 - 1.1e-06 28.7 0.3 0.091 12.9 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD22916.1 - 3.4e-06 27.2 0.2 0.19 11.9 0.1 3.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 PVD22916.1 - 0.00011 22.2 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain RsgA_GTPase PF03193.16 PVD22916.1 - 0.00081 19.3 0.1 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Ig_2 PF13895.6 PVD22916.1 - 0.0015 18.8 0.0 0.61 10.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain MeaB PF03308.16 PVD22916.1 - 0.0038 16.3 0.1 3.1 6.7 0.0 2.6 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 PVD22916.1 - 0.0087 15.9 0.1 0.22 11.3 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 PVD22916.1 - 0.011 15.8 0.0 0.15 12.2 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD22916.1 - 0.029 13.9 1.1 1.3 8.5 0.2 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PVD22916.1 - 0.032 14.8 0.3 0.095 13.2 0.3 2.0 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 PVD22916.1 - 0.034 14.4 1.0 0.09 13.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 PVD22916.1 - 0.039 13.7 0.2 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD22916.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 PVD22916.1 - 0.078 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TSP_1 PF00090.19 PVD22916.1 - 0.093 13.0 4.4 0.16 12.2 0.4 2.7 2 0 0 2 2 2 0 Thrombospondin type 1 domain TsaE PF02367.17 PVD22916.1 - 0.13 12.3 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PVD22916.1 - 0.18 12.3 1.2 0.3 11.6 0.4 1.7 2 0 0 2 2 1 0 AAA domain 7tm_2 PF00002.24 PVD22917.1 - 1e-09 38.1 15.7 1.5e-09 37.6 15.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 PVD22917.1 - 6.7e-06 25.4 16.0 6.8e-06 25.4 15.1 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 PVD22917.1 - 0.084 12.2 11.7 0.071 12.4 10.4 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PIF1 PF05970.14 PVD22918.1 - 6.2e-68 229.6 0.3 3.8e-51 174.4 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 PVD22918.1 - 7.4e-20 71.5 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD22918.1 - 1.4e-08 35.2 0.1 4.8e-08 33.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD22918.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PVD22918.1 - 0.00028 20.6 0.2 0.0012 18.6 0.0 2.2 2 1 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 PVD22918.1 - 0.00054 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PVD22918.1 - 0.00074 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Herpes_Helicase PF02689.14 PVD22918.1 - 0.00089 17.3 0.9 0.011 13.7 0.1 2.1 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 PVD22918.1 - 0.0021 17.8 1.1 2.7 7.7 0.1 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 PVD22918.1 - 0.0026 17.2 0.1 0.0049 16.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PVD22918.1 - 0.0027 18.1 0.1 0.0063 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 PVD22918.1 - 0.01 14.9 0.1 0.025 13.6 0.1 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 PVD22918.1 - 0.011 15.8 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 PVD22918.1 - 0.015 15.8 0.0 0.043 14.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 PVD22918.1 - 0.025 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PVD22918.1 - 0.034 13.6 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 PVD22918.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FliG_C PF01706.16 PVD22918.1 - 0.071 13.3 0.3 0.2 11.9 0.1 1.8 2 0 0 2 2 1 0 FliG C-terminal domain Ribosomal_L26 PF16906.5 PVD22918.1 - 0.14 12.7 0.1 0.43 11.1 0.1 1.8 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal TPR_2 PF07719.17 PVD22919.1 - 6.9e-08 32.0 0.0 0.63 10.3 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD22919.1 - 0.00025 21.6 1.0 0.017 15.9 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD22919.1 - 0.00039 20.1 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD22919.1 - 0.00071 20.0 0.6 0.0095 16.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD22919.1 - 0.00072 19.6 0.0 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD22919.1 - 0.0012 19.1 0.2 0.046 14.1 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD22919.1 - 0.0025 17.9 0.4 0.028 14.6 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD22919.1 - 0.015 15.9 0.0 4.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22919.1 - 0.018 14.7 0.0 8.5 6.2 0.0 2.8 2 1 1 3 3 3 0 TPR repeat ChAPs PF09295.10 PVD22919.1 - 0.11 11.5 0.2 0.19 10.7 0.2 1.4 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TSP_1 PF00090.19 PVD22920.1 - 5.4e-18 64.9 35.2 1.2e-08 35.0 14.2 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain PAN_1 PF00024.26 PVD22920.1 - 1.3e-07 31.4 0.6 1.3e-07 31.4 0.6 2.6 3 0 0 3 3 3 1 PAN domain PAN_4 PF14295.6 PVD22920.1 - 0.0054 16.6 2.6 0.008 16.1 0.5 2.4 2 0 0 2 2 2 1 PAN domain Chordopox_A33R PF05966.12 PVD22920.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.0 2 1 0 3 3 3 0 Chordopoxvirus A33R protein Ephrin_rec_like PF07699.13 PVD22921.1 - 5.8e-34 115.6 58.6 6.5e-12 45.0 5.4 8.6 7 2 2 9 9 7 5 Putative ephrin-receptor like VWA PF00092.28 PVD22921.1 - 3.8e-32 111.9 0.0 6.6e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HYR PF02494.16 PVD22921.1 - 1.2e-27 96.1 3.4 3e-13 49.9 0.2 2.6 2 0 0 2 2 2 2 HYR domain Pentaxin PF00354.17 PVD22921.1 - 2e-25 89.6 0.1 2e-24 86.4 0.1 2.1 1 1 0 1 1 1 1 Pentaxin family EGF PF00008.27 PVD22921.1 - 6.3e-22 77.5 100.0 6.7e-08 32.7 10.6 8.7 8 0 0 8 8 8 4 EGF-like domain Sushi PF00084.20 PVD22921.1 - 9.7e-21 74.1 20.5 3.1e-11 43.7 1.9 8.9 9 1 1 10 10 9 4 Sushi repeat (SCR repeat) hEGF PF12661.7 PVD22921.1 - 1.3e-14 54.2 93.9 4.5e-05 23.9 6.5 10.1 9 0 0 9 9 8 5 Human growth factor-like EGF VWA_2 PF13519.6 PVD22921.1 - 2.5e-11 44.2 0.0 6.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.6 PVD22921.1 - 4.9e-07 30.0 0.5 1.1e-06 28.8 0.5 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily VWA_CoxE PF05762.14 PVD22921.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein SMC_Nse1 PF07574.13 PVD22921.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex EGF_2 PF07974.13 PVD22921.1 - 0.061 13.7 96.5 0.085 13.2 12.3 8.7 7 1 0 7 7 7 0 EGF-like domain Laminin_G_2 PF02210.24 PVD22921.1 - 0.17 12.5 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Sushi PF00084.20 PVD22922.1 - 9.3e-83 272.7 43.1 1e-12 48.4 1.8 9.1 9 0 0 9 9 9 8 Sushi repeat (SCR repeat) cEGF PF12662.7 PVD22922.1 - 0.0023 17.8 41.3 0.066 13.2 0.2 8.1 8 0 0 8 8 8 5 Complement Clr-like EGF-like HRM PF02793.22 PVD22922.1 - 0.035 14.4 36.5 11 6.4 0.4 7.8 7 1 0 7 7 7 0 Hormone receptor domain ANATO PF01821.18 PVD22922.1 - 2.4 9.1 12.8 1.4 9.8 0.4 4.7 4 0 0 4 4 4 0 Anaphylotoxin-like domain U71 PF17474.2 PVD22922.1 - 3.5 7.6 7.1 6.8 6.7 0.2 3.5 3 0 0 3 3 3 0 Tegument protein UL11 homolog Sushi PF00084.20 PVD22923.1 - 1.8e-20 73.3 4.7 3.2e-09 37.2 0.1 3.4 3 1 0 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 PVD22923.1 - 0.0047 17.2 3.1 0.0048 17.2 0.0 2.3 3 0 0 3 3 3 1 Hormone receptor domain DUF3506 PF12014.8 PVD22924.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Sushi PF00084.20 PVD22925.1 - 3.1e-10 40.5 3.3 6.1e-06 26.8 0.2 2.3 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) DUF5042 PF16445.5 PVD22926.1 - 0.087 11.2 0.0 0.15 10.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5042) Sugar_tr PF00083.24 PVD22927.1 - 1e-67 229.0 24.3 1.2e-67 228.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD22927.1 - 3.3e-22 78.9 31.5 3.3e-22 78.9 31.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD22928.1 - 1.4e-68 231.8 38.3 1.1e-35 123.4 13.0 5.0 3 2 2 5 5 5 4 Sugar (and other) transporter MFS_1 PF07690.16 PVD22928.1 - 8.9e-20 70.9 46.5 2e-08 33.6 23.4 4.3 2 1 1 4 4 4 3 Major Facilitator Superfamily LURAP PF14854.6 PVD22931.1 - 0.00057 19.8 0.3 0.0012 18.8 0.3 1.5 1 0 0 1 1 1 1 Leucine rich adaptor protein LURAP PF14854.6 PVD22932.1 - 0.00069 19.5 1.3 0.00069 19.5 1.3 1.8 1 1 1 2 2 2 1 Leucine rich adaptor protein RhoGEF67_u1 PF16615.5 PVD22934.1 - 0.42 11.1 4.5 0.73 10.4 4.5 1.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 Sushi PF00084.20 PVD22935.1 - 0.0012 19.4 0.2 0.0026 18.3 0.2 1.6 1 1 0 1 1 1 1 Sushi repeat (SCR repeat) DUF281 PF03436.13 PVD22935.1 - 0.16 12.4 3.5 4.9 7.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF281) PAN_1 PF00024.26 PVD22936.1 - 0.00011 22.1 1.6 0.0002 21.3 1.6 1.4 1 0 0 1 1 1 1 PAN domain Sushi PF00084.20 PVD22936.1 - 0.006 17.2 1.3 0.011 16.3 0.2 2.1 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) PAN_4 PF14295.6 PVD22936.1 - 0.031 14.2 0.5 0.07 13.0 0.5 1.7 1 0 0 1 1 1 0 PAN domain DUF281 PF03436.13 PVD22936.1 - 0.16 12.4 4.7 3.2 8.2 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF281) Sulfatase PF00884.23 PVD22937.1 - 3.9e-32 111.9 0.0 1.5e-18 67.2 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 PVD22937.1 - 1.4e-05 25.8 0.0 3.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD22937.1 - 0.014 15.6 0.3 0.095 13.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Sulfatase PF00884.23 PVD22938.1 - 9e-29 100.8 0.0 3e-15 56.4 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 PVD22938.1 - 6.1e-06 27.0 0.0 1.3e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD22938.1 - 0.027 14.7 1.6 0.073 13.3 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) Peptidase_M4_C PF02868.15 PVD22939.1 - 4e-28 98.4 0.0 5.8e-13 49.0 0.0 3.4 2 1 0 2 2 2 2 Thermolysin metallopeptidase, alpha-helical domain Sulfatase PF00884.23 PVD22939.1 - 3.2e-26 92.4 0.0 1.7e-12 47.4 0.0 2.5 1 1 1 2 2 2 2 Sulfatase Peptidase_M4 PF01447.18 PVD22939.1 - 1.2e-17 64.8 0.0 5.2e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 Thermolysin metallopeptidase, catalytic domain Sulfatase_C PF14707.6 PVD22939.1 - 1.3e-05 25.9 0.0 2.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Peptidase_M36 PF02128.15 PVD22939.1 - 0.022 14.0 0.1 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Fungalysin metallopeptidase (M36) DUF4976 PF16347.5 PVD22939.1 - 0.18 12.1 0.7 0.39 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Sulfatase PF00884.23 PVD22940.1 - 4.3e-48 164.3 0.1 6.2e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase zf-C3HC4_3 PF13920.6 PVD22940.1 - 9.2e-09 35.0 7.3 1.9e-08 34.0 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD22940.1 - 1.8e-07 31.0 9.0 5.4e-07 29.5 9.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD22940.1 - 2.7e-07 30.5 8.2 3.6e-07 30.1 5.4 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD22940.1 - 1.5e-06 27.9 8.9 3.8e-06 26.7 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sulfatase_C PF14707.6 PVD22940.1 - 2.1e-06 28.5 0.0 1.1e-05 26.2 0.0 2.3 3 0 0 3 3 1 1 C-terminal region of aryl-sulfatase Prok-RING_4 PF14447.6 PVD22940.1 - 5.4e-06 26.2 8.1 5.4e-06 26.2 8.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD22940.1 - 2e-05 24.9 9.7 5.4e-05 23.4 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD22940.1 - 5.4e-05 22.9 9.7 0.00015 21.6 9.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD22940.1 - 0.00021 21.4 10.5 0.0005 20.2 10.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 PVD22940.1 - 0.027 14.7 2.6 0.055 13.7 2.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-ANAPC11 PF12861.7 PVD22940.1 - 0.17 11.9 2.9 0.42 10.7 2.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 PVD22940.1 - 0.25 11.2 4.7 0.74 9.7 4.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain NodZ PF05830.11 PVD22941.1 - 5.6e-05 22.1 0.1 0.0014 17.5 0.0 2.3 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) SBP_bac_3 PF00497.20 PVD22941.1 - 0.0026 17.2 0.0 0.033 13.6 0.0 2.4 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SH3_2 PF07653.17 PVD22943.1 - 4.8e-06 26.2 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD22943.1 - 1e-05 25.3 0.2 7.8e-05 22.5 0.0 2.3 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PVD22943.1 - 0.041 13.5 0.4 12 5.7 0.0 2.9 3 0 0 3 3 3 0 SH3 domain SH3_2 PF07653.17 PVD22944.1 - 2.2e-05 24.1 0.1 5.4e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain NodZ PF05830.11 PVD22944.1 - 7.7e-05 21.6 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) SH3_9 PF14604.6 PVD22944.1 - 0.00023 21.0 0.0 0.0014 18.5 0.0 2.2 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22944.1 - 0.09 12.4 0.6 16 5.2 0.0 3.0 3 0 0 3 3 3 0 SH3 domain Acyl_CoA_thio PF02551.15 PVD22944.1 - 0.1 12.5 0.2 3.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Acyl-CoA thioesterase rRNA_proc-arch PF13234.6 PVD22944.1 - 0.1 12.5 0.2 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 rRNA-processing arch domain NodZ PF05830.11 PVD22945.1 - 3.2e-05 22.9 0.1 4.6e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) SH3_9 PF14604.6 PVD22945.1 - 3.3e-05 23.7 0.1 0.00035 20.4 0.1 2.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD22945.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22945.1 - 0.022 14.4 1.3 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 SH3 domain NodZ PF05830.11 PVD22946.1 - 2e-05 23.6 0.1 3.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 PVD22946.1 - 4.3e-05 23.4 0.2 8.7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase SH3_2 PF07653.17 PVD22946.1 - 0.013 15.1 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 PVD22946.1 - 0.041 13.7 0.0 0.3 11.0 0.0 2.3 1 1 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 PVD22946.1 - 0.17 11.5 0.2 4 7.1 0.0 2.8 3 0 0 3 3 3 0 SH3 domain SH3_2 PF07653.17 PVD22947.1 - 3e-06 26.8 0.1 8.4e-06 25.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain NodZ PF05830.11 PVD22947.1 - 0.00024 20.1 0.0 0.00054 18.9 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) SH3_9 PF14604.6 PVD22947.1 - 0.00049 19.9 0.0 0.0033 17.2 0.0 2.3 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22947.1 - 0.1 12.2 0.6 9.5 5.9 0.0 3.0 3 0 0 3 3 3 0 SH3 domain rRNA_proc-arch PF13234.6 PVD22948.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain SH3_9 PF14604.6 PVD22949.1 - 5.9e-05 22.8 0.0 0.00047 19.9 0.0 2.4 1 1 0 1 1 1 1 Variant SH3 domain NodZ PF05830.11 PVD22949.1 - 0.00014 20.8 0.2 0.00027 19.9 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) SH3_2 PF07653.17 PVD22949.1 - 0.00048 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD22949.1 - 0.11 12.2 0.7 14 5.4 0.0 2.9 3 0 0 3 3 3 0 SH3 domain DUF4371 PF14291.6 PVD22950.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) DUF5448 PF17526.2 PVD22950.1 - 0.011 16.0 0.8 0.23 11.7 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5448) zf-C2H2_12 PF18658.1 PVD22950.1 - 0.039 13.5 1.1 0.056 13.0 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type NodZ PF05830.11 PVD22951.1 - 4e-05 22.6 0.0 6.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 PVD22951.1 - 5.5e-05 23.0 0.1 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase SH3_2 PF07653.17 PVD22951.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 PVD22951.1 - 0.059 13.2 0.0 0.44 10.4 0.0 2.4 1 1 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 PVD22951.1 - 0.18 11.4 0.3 5.2 6.8 0.0 2.8 3 0 0 3 3 3 0 SH3 domain TRAPPC10 PF12584.8 PVD22953.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Y_phosphatase PF00102.27 PVD22955.1 - 1e-47 162.7 1.6 1.5e-37 129.4 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Drf_DAD PF06345.11 PVD22955.1 - 0.2 11.7 0.0 0.5 10.5 0.0 1.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain fn3 PF00041.21 PVD22956.1 - 8.4e-44 147.8 5.4 7.9e-17 61.4 0.7 5.6 5 0 0 5 5 5 4 Fibronectin type III domain Y_phosphatase PF00102.27 PVD22956.1 - 1.9e-31 109.4 0.0 3.2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Kringle PF00051.18 PVD22956.1 - 6.1e-17 61.7 7.3 1.5e-16 60.5 7.3 1.7 1 0 0 1 1 1 1 Kringle domain Pur_ac_phosph_N PF16656.5 PVD22956.1 - 3.9e-12 46.6 0.4 0.0052 17.3 0.2 4.5 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD22956.1 - 3.3e-07 30.6 0.0 0.013 15.8 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 PVD22956.1 - 0.0036 17.7 0.0 5.3 7.5 0.0 3.3 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) PTP_tm PF18861.1 PVD22956.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CHS5_N PF16892.5 PVD22956.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus LRRC37 PF15779.5 PVD22956.1 - 0.15 12.4 1.5 4.6 7.7 0.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeat-containing protein 37 family Pkinase_Tyr PF07714.17 PVD22958.1 - 1.3e-97 326.2 0.0 1.6e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD22958.1 - 7.2e-50 169.8 0.0 9.8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD22958.1 - 3.5e-27 94.3 0.6 8.8e-27 93.0 0.2 1.9 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 PVD22958.1 - 2e-18 65.7 0.3 6.9e-18 64.0 0.2 2.0 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 PVD22958.1 - 2.5e-13 49.6 0.1 1.3e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PVD22958.1 - 4.3e-10 39.1 0.0 5.7e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 PVD22958.1 - 3.9e-06 26.1 0.0 7.3e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD22958.1 - 0.013 15.4 0.0 0.41 10.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.11 PVD22958.1 - 0.024 14.9 0.1 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Kdo PF06293.14 PVD22958.1 - 0.043 13.2 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD22958.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UCH PF00443.29 PVD22959.1 - 6.7e-42 143.8 0.0 1.4e-41 142.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD22959.1 - 5e-32 111.8 0.0 1.5e-31 110.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 PVD22959.1 - 4.5e-06 26.4 0.2 1.2e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zinc_ribbon_2 PF13240.6 PVD22959.1 - 0.12 12.1 0.4 0.51 10.1 0.4 2.1 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.25 PVD22960.1 - 2e-69 233.9 0.0 2.3e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22960.1 - 8.2e-33 113.8 0.0 1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD22960.1 - 8.7e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD22960.1 - 0.00071 18.6 0.1 0.001 18.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain fn3 PF00041.21 PVD22964.1 - 2.3e-11 43.9 4.4 0.0001 22.6 0.2 4.3 4 0 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD22964.1 - 0.024 15.2 2.2 0.26 11.9 0.1 2.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF4690 PF15756.5 PVD22964.1 - 0.037 14.6 0.2 0.12 13.0 0.2 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage fn3 PF00041.21 PVD22965.1 - 0.0013 19.0 0.2 0.0052 17.1 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain fn3 PF00041.21 PVD22966.1 - 3.1e-07 30.6 0.3 0.14 12.5 0.0 4.2 4 0 0 4 4 4 2 Fibronectin type III domain T2SSS_2 PF16549.5 PVD22966.1 - 0.051 13.6 0.3 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS) pilotin, S protein YfzA PF14118.6 PVD22967.1 - 0.074 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 YfzA-like protein Pkinase PF00069.25 PVD22968.1 - 9.5e-49 166.1 0.0 1.8e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD22968.1 - 1.4e-46 158.9 0.0 2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD22968.1 - 7e-08 32.1 0.2 1.5e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PVD22968.1 - 1.3e-06 27.5 0.0 3.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD22968.1 - 0.0019 18.2 0.4 0.18 11.7 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD22968.1 - 0.094 11.6 0.2 0.21 10.5 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pro_isomerase PF00160.21 PVD22969.1 - 3.5e-44 150.8 0.0 3.5e-44 150.8 0.0 3.0 3 1 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Hist_deacetyl PF00850.19 PVD22970.1 - 2.3e-79 267.0 0.4 2.3e-79 267.0 0.4 1.3 2 0 0 2 2 2 1 Histone deacetylase domain WD40 PF00400.32 PVD22971.1 - 2e-19 69.6 20.9 6.5e-06 26.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD22971.1 - 1.2e-10 41.5 2.5 0.012 15.9 0.1 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD22971.1 - 0.00037 20.4 0.2 0.078 12.9 0.0 3.4 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD22971.1 - 0.054 12.1 3.0 0.56 8.8 0.4 2.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 FHA PF00498.26 PVD22971.1 - 0.09 13.1 0.4 0.38 11.2 0.1 2.2 2 0 0 2 2 2 0 FHA domain RTC_insert PF05189.13 PVD22972.1 - 7.9e-24 84.2 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 PVD22972.1 - 2.9e-09 36.4 0.0 3.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Peptidase_M16_M PF16187.5 PVD22973.1 - 2.3e-73 246.9 0.2 4.9e-73 245.8 0.2 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PVD22973.1 - 8.6e-37 126.4 0.0 4.2e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PVD22973.1 - 1.1e-23 84.3 0.2 1.8e-10 41.2 0.1 3.9 4 1 0 4 4 4 2 Peptidase M16 inactive domain LRR_9 PF14580.6 PVD22974.1 - 4.2e-17 62.2 1.0 4.2e-17 62.2 1.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 PVD22974.1 - 1.6e-08 34.7 14.2 3e-05 24.3 1.5 4.4 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD22974.1 - 9.2e-08 31.7 4.0 3.4e-06 26.7 3.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 PVD22974.1 - 2 8.7 9.2 15 6.0 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 PVD22974.1 - 3.8 8.4 7.5 2.1e+02 3.1 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Geminin PF07412.12 PVD22975.1 - 6e-20 71.8 14.4 2e-16 60.3 8.6 2.2 1 1 1 2 2 2 2 Geminin NYD-SP28_assoc PF14775.6 PVD22975.1 - 0.2 11.8 4.5 0.14 12.3 2.2 1.9 1 1 1 2 2 2 0 Sperm tail C-terminal domain Helo_like_N PF17111.5 PVD22975.1 - 0.59 9.5 6.2 0.066 12.6 1.6 1.7 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins CRT10 PF08728.10 PVD22975.1 - 0.92 7.6 4.5 1.2 7.2 4.5 1.1 1 0 0 1 1 1 0 CRT10 Sec7 PF01369.20 PVD22977.1 - 3.9e-62 209.2 0.7 1.1e-61 207.8 0.7 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PVD22977.1 - 2e-39 135.1 5.4 3.5e-39 134.2 1.3 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PVD22977.1 - 2.7e-34 116.8 0.2 2.7e-34 116.8 0.2 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 PVD22977.1 - 1.3e-29 103.2 6.2 7.6e-29 100.6 0.4 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Presenilin PF01080.17 PVD22977.1 - 7 5.3 7.8 12 4.5 7.8 1.3 1 0 0 1 1 1 0 Presenilin JAB PF01398.21 PVD22978.1 - 4.5e-33 113.7 0.0 7.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 PVD22978.1 - 5.5e-25 88.1 0.5 9.7e-25 87.3 0.5 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 PVD22978.1 - 2.2e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PVD22978.1 - 0.00095 19.3 0.1 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) DUF389 PF04087.14 PVD22979.1 - 5.6e-42 143.1 7.7 5.6e-42 143.1 7.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Jiraiya PF15038.6 PVD22979.1 - 0.81 9.1 5.2 3.1 7.2 0.2 2.5 2 0 0 2 2 2 0 Jiraiya HlyIII PF03006.20 PVD22980.1 - 3.1e-17 63.0 10.8 3.2e-13 49.9 6.3 2.3 1 1 1 2 2 2 2 Haemolysin-III related Pkinase_Tyr PF07714.17 PVD22981.1 - 1.7e-93 312.7 0.0 2.6e-93 312.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.13 PVD22981.1 - 1.8e-48 163.9 5.1 4.1e-48 162.7 5.1 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.25 PVD22981.1 - 5.2e-48 163.7 0.0 9.2e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain FERM_N_2 PF18038.1 PVD22981.1 - 4.1e-21 75.6 0.3 1.4e-20 73.9 0.0 2.1 2 0 0 2 2 1 1 FERM N-terminal domain FERM_M PF00373.18 PVD22981.1 - 9e-12 45.4 0.2 4e-11 43.3 0.2 2.2 1 0 0 1 1 1 1 FERM central domain FERM_F2 PF18377.1 PVD22981.1 - 0.00026 20.9 0.5 0.0007 19.5 0.5 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Haspin_kinase PF12330.8 PVD22981.1 - 0.0091 15.0 0.8 0.015 14.2 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain FERM_f0 PF16511.5 PVD22981.1 - 0.016 15.5 0.1 0.061 13.6 0.0 2.0 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF1284 PF06935.11 PVD22981.1 - 0.041 14.3 1.8 0.14 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) DUF1241 PF06840.11 PVD22981.1 - 0.058 13.0 0.2 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Kinase-like PF14531.6 PVD22981.1 - 0.065 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 PVD22982.1 - 2e-06 27.9 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PVD22982.1 - 0.003 17.2 0.8 0.063 12.9 0.1 2.2 1 1 1 2 2 2 1 RIO1 family AsnA PF03590.15 PVD22982.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate-ammonia ligase 2OG-FeII_Oxy PF03171.20 PVD22983.1 - 0.00063 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SBP_bac_3 PF00497.20 PVD22983.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DIOX_N PF14226.6 PVD22984.1 - 2.9e-21 76.4 0.1 4.8e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal COX5B PF01215.19 PVD22985.1 - 1e-19 70.5 0.0 1.1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb TBK1_ULD PF18396.1 PVD22986.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 PVD22986.1 - 0.11 12.3 0.0 0.11 12.3 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin family Phe_ZIP PF08916.11 PVD22986.1 - 0.15 12.8 0.6 0.52 11.1 0.6 1.9 1 0 0 1 1 1 0 Phenylalanine zipper PqqD PF05402.12 PVD22986.1 - 5.4 7.4 5.8 16 5.9 0.1 4.1 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) SYCP2_SLD PF18584.1 PVD22987.1 - 2.1e-18 66.6 1.3 5.2e-18 65.3 0.2 2.4 2 0 0 2 2 2 1 Synaptonemal complex 2 Spt16M-like domain GCM PF03615.15 PVD22988.1 - 4.9e-73 243.6 2.6 7.1e-73 243.1 2.6 1.2 1 0 0 1 1 1 1 GCM motif protein TIR PF01582.20 PVD22989.1 - 0.00026 20.8 1.1 0.00049 19.9 1.1 1.4 1 0 0 1 1 1 1 TIR domain EGF PF00008.27 PVD22989.1 - 0.019 15.2 43.3 0.043 14.1 12.0 3.6 3 0 0 3 3 3 0 EGF-like domain TIR_2 PF13676.6 PVD22989.1 - 0.09 13.4 0.2 0.27 11.9 0.1 1.8 2 0 0 2 2 2 0 TIR domain EGF_2 PF07974.13 PVD22989.1 - 8.3 6.9 49.1 0.38 11.1 10.4 3.8 3 0 0 3 3 3 0 EGF-like domain Alpha-amylase PF00128.24 PVD22991.1 - 2.4e-21 76.7 0.0 1.3e-19 71.0 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain EGF PF00008.27 PVD22992.1 - 2e-11 44.0 47.6 2.5e-05 24.5 10.0 5.6 5 1 0 5 5 5 5 EGF-like domain hEGF PF12661.7 PVD22992.1 - 2.1e-05 25.0 40.9 0.0041 17.7 6.3 6.3 6 1 0 6 6 6 4 Human growth factor-like EGF EGF_2 PF07974.13 PVD22992.1 - 0.0023 18.2 52.2 0.0036 17.6 4.7 5.3 5 0 0 5 5 5 2 EGF-like domain Pacifastin_I PF05375.13 PVD22993.1 - 0.016 14.9 17.9 0.61 9.8 0.1 3.5 3 0 0 3 3 3 0 Pacifastin inhibitor (LCMII) PSP94 PF05825.11 PVD22993.1 - 2 9.0 8.7 1.4e+02 3.1 0.0 3.1 2 1 1 3 3 3 0 Beta-microseminoprotein (PSP-94) Pacifastin_I PF05375.13 PVD22994.1 - 2.8e-11 43.0 40.1 9.5e-07 28.4 6.4 3.3 3 0 0 3 3 3 3 Pacifastin inhibitor (LCMII) zf-nanos PF05741.13 PVD22995.1 - 1.2e-22 79.9 6.0 2.7e-22 78.7 6.0 1.7 1 0 0 1 1 1 1 Nanos RNA binding domain CpXC PF14353.6 PVD22995.1 - 0.011 15.8 2.4 0.02 14.9 2.4 1.5 1 0 0 1 1 1 0 CpXC protein zf-HIT PF04438.16 PVD22995.1 - 0.098 12.5 0.9 0.098 12.5 0.9 2.6 3 0 0 3 3 3 0 HIT zinc finger DnaJ_CXXCXGXG PF00684.19 PVD22995.1 - 0.13 12.7 3.0 0.42 11.0 3.0 1.9 1 1 0 1 1 1 0 DnaJ central domain HypA PF01155.19 PVD22995.1 - 0.22 11.6 4.9 2.4 8.2 4.9 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 PVD22995.1 - 5.1 6.6 8.0 0.47 9.9 0.5 3.1 4 0 0 4 4 4 0 zinc-ribbon domain BSMAP PF12280.8 PVD22996.1 - 1.4e-28 100.4 0.2 1.8e-28 100.0 0.2 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein Peptidase_C1 PF00112.23 PVD22997.1 - 1.4e-71 241.1 0.5 2.2e-71 240.4 0.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD22997.1 - 1.8e-10 41.1 3.2 4.4e-10 39.9 3.2 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD22997.1 - 0.0085 14.9 0.3 0.26 10.0 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family TPR_1 PF00515.28 PVD22998.1 - 0.0028 17.4 1.2 0.042 13.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD22998.1 - 0.045 13.4 2.6 0.15 11.8 1.4 2.4 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 PVD22998.1 - 0.047 13.8 1.0 0.29 11.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 PVD22998.1 - 0.087 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Lig_chan-Glu_bd PF10613.9 PVD23000.1 - 2e-25 89.2 0.1 1.8e-24 86.1 0.0 2.3 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD23000.1 - 2.6e-21 76.1 0.1 5.5e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PVD23000.1 - 2.7e-20 72.7 0.0 5.4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 PVD23000.1 - 2.6e-07 30.1 0.2 0.00014 21.1 0.2 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region PDCD7 PF16021.5 PVD23000.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Programmed cell death protein 7 ABC_membrane PF00664.23 PVD23000.1 - 0.15 11.7 2.1 0.22 11.2 0.2 2.2 3 0 0 3 3 3 0 ABC transporter transmembrane region Bax1-I PF01027.20 PVD23000.1 - 0.27 11.1 3.2 0.57 10.0 3.2 1.5 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Ribosomal_60s PF00428.19 PVD23000.1 - 0.65 10.6 7.1 2.1 9.0 7.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUDIX PF00293.28 PVD23001.1 - 0.0017 18.4 0.1 0.51 10.4 0.1 3.0 2 1 1 3 3 3 2 NUDIX domain DUF3040 PF11239.8 PVD23003.1 - 1.6 9.1 7.5 0.5 10.7 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1943 PF09172.11 PVD23004.1 - 2.2e-72 243.9 0.4 5.1e-72 242.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Vitellogenin_N PF01347.22 PVD23004.1 - 9.6e-64 215.9 0.0 1.4e-53 182.3 0.0 2.3 1 1 1 2 2 2 2 Lipoprotein amino terminal region DUF1081 PF06448.11 PVD23004.1 - 5.2e-06 26.8 3.7 0.0002 21.7 0.0 4.2 3 1 0 3 3 3 1 Domain of Unknown Function (DUF1081) HEAT_2 PF13646.6 PVD23004.1 - 0.024 15.0 1.7 0.16 12.4 0.7 2.6 2 1 1 3 3 3 0 HEAT repeats Big_9 PF17963.1 PVD23005.1 - 0.022 15.5 1.1 0.18 12.6 0.7 2.3 2 0 0 2 2 2 0 Bacterial Ig domain Milton PF12448.8 PVD23005.1 - 0.039 14.1 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin associated protein VWD PF00094.25 PVD23006.1 - 1.1e-23 84.2 1.4 1.5e-23 83.8 0.2 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 PVD23006.1 - 3.7e-05 24.1 3.4 9.3e-05 22.8 3.4 1.7 1 0 0 1 1 1 1 C8 domain CdvA PF18822.1 PVD23006.1 - 0.019 14.8 1.8 0.23 11.3 0.6 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SHE3 PF17078.5 PVD23006.1 - 0.032 14.0 0.5 0.069 12.9 0.5 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Apolipoprotein PF01442.18 PVD23006.1 - 1.1 9.2 10.2 34 4.2 0.8 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain OmpH PF03938.14 PVD23006.1 - 5.9 7.2 7.0 3.1 8.1 3.4 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Profilin PF00235.19 PVD23007.1 - 2.5e-22 79.5 0.0 2.7e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Profilin LMBR1 PF04791.16 PVD23009.1 - 2.1e-08 33.6 25.1 0.0022 17.0 5.1 3.4 1 1 2 3 3 3 3 LMBR1-like membrane protein Baculo_11_kDa PF06143.11 PVD23009.1 - 2.3 7.9 16.0 1.3 8.7 0.4 4.2 4 0 0 4 4 4 0 Baculovirus 11 kDa family DUF3040 PF11239.8 PVD23009.1 - 2.3 8.5 7.2 0.79 10.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Renin_r PF07850.14 PVD23009.1 - 2.4 8.8 14.4 2.4 8.8 1.4 4.2 3 2 0 3 3 3 0 Renin receptor-like protein Ly49 PF08391.10 PVD23009.1 - 8.5 6.8 8.5 4.6 7.6 1.1 3.0 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region SWIRM PF04433.17 PVD23010.1 - 9.2e-21 74.0 0.1 5e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 PVD23010.1 - 3.5e-14 52.7 0.2 9.4e-14 51.3 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 PVD23010.1 - 2.8e-12 46.7 0.2 9.5e-12 44.9 0.2 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PVD23010.1 - 4.2e-07 29.7 0.3 9.7e-07 28.6 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 PVD23010.1 - 2.9e-06 27.4 0.1 8.6e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PVD23010.1 - 7.2e-06 25.8 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like UPF0172 PF03665.13 PVD23010.1 - 0.00039 20.5 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF1932 PF09130.11 PVD23010.1 - 0.08 12.9 0.2 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) O-FucT PF10250.9 PVD23011.1 - 3.9e-75 253.7 0.0 4.6e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase IL12 PF03039.14 PVD23011.1 - 0.18 11.1 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit XK-related PF09815.9 PVD23012.1 - 9.5e-51 172.9 34.6 1.3e-50 172.4 34.6 1.2 1 0 0 1 1 1 1 XK-related protein Peptidase_M54 PF07998.11 PVD23012.1 - 0.095 12.7 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M54 XK-related PF09815.9 PVD23013.1 - 1.2e-18 67.3 28.0 1.8e-18 66.8 28.0 1.2 1 0 0 1 1 1 1 XK-related protein SPX PF03105.19 PVD23015.1 - 0.59 10.0 13.9 0.76 9.6 13.9 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 PVD23015.1 - 0.68 8.4 10.4 0.76 8.3 10.4 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 PVD23015.1 - 0.84 8.1 12.5 1.1 7.7 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 PVD23015.1 - 5.1 4.1 11.2 5.5 4.0 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DNA_primase_lrg PF04104.14 PVD23016.1 - 4.8e-81 272.1 0.0 6.8e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RRM_1 PF00076.22 PVD23017.1 - 1.1e-28 98.8 0.0 2.9e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 PVD23017.1 - 1.5e-17 64.3 4.1 3.6e-17 63.1 4.1 1.7 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins Mistic PF11458.8 PVD23017.1 - 0.066 13.2 0.4 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 Membrane-integrating protein Mistic WD40 PF00400.32 PVD23018.1 - 1.4e-17 63.7 11.6 1.5e-06 28.8 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23018.1 - 9e-09 35.5 1.6 0.19 12.1 0.0 5.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD23018.1 - 8.9e-05 21.3 4.1 0.00039 19.2 1.3 2.8 2 2 1 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PVD23018.1 - 0.063 13.3 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region HhH-GPD PF00730.25 PVD23019.1 - 8.5e-21 74.4 0.0 1.8e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 PVD23019.1 - 1.5e-20 73.2 0.1 5e-20 71.5 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 PVD23019.1 - 5.5e-08 32.3 0.1 1.3e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 PVD23019.1 - 0.00015 22.0 6.3 0.0005 20.3 6.3 2.0 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III PDEase_I PF00233.19 PVD23029.1 - 3.4e-93 311.7 4.0 6.1e-93 310.9 4.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 PVD23029.1 - 3.1e-49 166.5 3.1 5.4e-37 127.1 1.0 2.9 1 1 1 2 2 2 2 Phosphodiesterase 4 upstream conserved regions (UCR) Neuralized PF07177.12 PVD23030.1 - 5e-31 107.7 0.0 1.1e-30 106.6 0.0 1.7 1 0 0 1 1 1 1 Neuralized TIR_2 PF13676.6 PVD23030.1 - 6.1e-23 81.7 0.0 1.4e-21 77.3 0.0 3.0 3 0 0 3 3 3 1 TIR domain COR PF16095.5 PVD23030.1 - 2.8e-19 69.7 0.0 5.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 PVD23030.1 - 1.3e-10 41.6 0.1 4.5e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 PVD23030.1 - 8.2e-08 32.3 0.7 2.1e-07 31.0 0.4 1.9 2 0 0 2 2 2 1 Death domain Ras PF00071.22 PVD23030.1 - 3.3e-05 23.5 0.1 7.2e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Ras family TIR PF01582.20 PVD23030.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain NB-ARC PF00931.22 PVD23030.1 - 0.037 13.2 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 PVD23030.1 - 0.18 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-B_box PF00643.24 PVD23031.1 - 1.1e-10 41.5 1.7 1.1e-10 41.5 1.7 4.4 5 0 0 5 5 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD23031.1 - 3.6e-08 33.3 8.2 3.6e-08 33.3 8.2 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD23031.1 - 5.4e-08 32.6 9.2 5.4e-08 32.6 9.2 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD23031.1 - 2e-07 31.1 11.7 2e-07 31.1 11.7 3.9 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD23031.1 - 3.8e-07 29.8 10.9 3.8e-07 29.8 10.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD23031.1 - 1.5e-06 28.0 7.6 1.5e-06 28.0 7.6 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD23031.1 - 3.5e-06 26.9 9.1 3.5e-06 26.9 9.1 3.6 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD23031.1 - 2e-05 24.8 8.6 2e-05 24.8 8.6 3.6 3 0 0 3 3 3 1 Ring finger domain FYVE_2 PF02318.16 PVD23031.1 - 0.00063 19.9 16.0 0.028 14.6 2.0 3.8 3 0 0 3 3 3 2 FYVE-type zinc finger zf-RING_11 PF17123.5 PVD23031.1 - 0.019 14.7 4.2 0.019 14.7 4.2 3.5 2 1 0 2 2 2 0 RING-like zinc finger DUF3583 PF12126.8 PVD23031.1 - 0.036 13.5 2.0 0.059 12.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) T6PP_N PF18572.1 PVD23031.1 - 0.089 12.6 0.4 0.22 11.3 0.4 1.7 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain zf-RING_4 PF14570.6 PVD23031.1 - 0.29 10.9 32.0 0.49 10.2 6.4 3.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Tnp_zf-ribbon_2 PF13842.6 PVD23031.1 - 2.9 8.8 32.7 0.79 10.6 6.4 3.9 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon IBR PF01485.21 PVD23031.1 - 4.9 7.5 27.8 1.8 8.9 10.2 3.5 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain EMP70 PF02990.16 PVD23032.1 - 5.3e-211 701.8 14.8 7.8e-211 701.2 14.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Patched PF02460.18 PVD23033.1 - 5.8e-90 302.5 25.2 1e-89 301.7 25.2 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD23033.1 - 2.9e-38 131.1 3.6 2.9e-38 131.1 3.6 3.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Ribosomal_L7Ae PF01248.26 PVD23034.1 - 0.055 13.2 0.0 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ras PF00071.22 PVD23035.1 - 7.1e-50 168.8 0.1 8.8e-50 168.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD23035.1 - 1.1e-26 93.5 0.1 5.3e-26 91.2 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD23035.1 - 2.2e-16 59.8 0.0 2.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD23035.1 - 1.6e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PVD23035.1 - 8.2e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PVD23035.1 - 0.0029 17.7 0.4 0.0057 16.7 0.4 1.8 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 PVD23035.1 - 0.0046 16.5 0.0 0.029 13.9 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PVD23035.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 PVD23035.1 - 0.027 13.8 0.1 0.051 12.9 0.1 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PVD23035.1 - 0.053 13.4 0.1 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 PVD23035.1 - 0.069 12.5 0.4 0.17 11.2 0.2 1.7 1 1 0 2 2 2 0 AIG1 family Septin PF00735.18 PVD23035.1 - 0.074 12.3 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Septin AAA PF00004.29 PVD23035.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Snf7 PF03357.21 PVD23037.1 - 0.047 13.3 0.0 0.081 12.5 0.0 1.4 1 1 0 1 1 1 0 Snf7 Il13Ra_Ig PF18001.1 PVD23037.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain RVT_1 PF00078.27 PVD23038.1 - 2.4e-27 95.9 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ISK_Channel PF02060.15 PVD23039.1 - 0.00052 19.7 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel SRTM1 PF15872.5 PVD23039.1 - 0.035 14.3 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF4113 PF13438.6 PVD23041.1 - 0.086 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) IL17 PF06083.11 PVD23042.1 - 0.00053 20.4 0.4 0.0014 19.1 0.4 1.6 1 0 0 1 1 1 1 Interleukin-17 Noggin PF05806.12 PVD23042.1 - 0.27 11.1 5.6 1.9 8.4 3.3 2.3 1 1 0 2 2 2 0 Noggin IL17 PF06083.11 PVD23043.1 - 0.0019 18.6 0.9 0.0051 17.3 0.9 1.7 1 0 0 1 1 1 1 Interleukin-17 Noggin PF05806.12 PVD23043.1 - 0.11 12.4 8.4 0.37 10.7 4.9 2.4 1 1 0 2 2 2 0 Noggin LRR_8 PF13855.6 PVD23047.1 - 1.1e-34 118.0 40.2 4.4e-10 39.2 0.2 6.9 4 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PVD23047.1 - 2.9e-33 113.3 47.3 3.7e-05 24.0 3.0 9.1 7 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD23047.1 - 3.3e-10 39.1 30.0 0.97 10.2 0.3 12.3 12 2 1 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.6 PVD23047.1 - 7.7e-09 35.3 16.2 0.0035 16.9 0.2 4.6 3 2 2 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 PVD23047.1 - 5.6e-05 22.9 37.9 8.9 6.7 0.1 12.4 14 0 0 14 14 14 5 Leucine Rich repeat Hydrophob_seed PF14547.6 PVD23047.1 - 0.008 16.4 0.2 0.018 15.3 0.2 1.5 1 0 0 1 1 1 1 Hydrophobic seed protein CAAP1 PF15335.6 PVD23047.1 - 1.3 9.6 6.5 0.81 10.3 2.7 2.7 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 CARD PF00619.21 PVD23048.1 - 1.3e-09 37.9 0.0 4.9e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain TPR_12 PF13424.6 PVD23048.1 - 6.2e-07 29.6 4.2 0.0087 16.3 0.0 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD23048.1 - 0.00027 20.9 0.5 0.0015 18.6 0.5 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD23048.1 - 0.00039 20.2 2.8 0.099 12.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD23048.1 - 0.00064 19.2 9.8 0.0015 18.0 0.5 3.6 2 2 1 4 4 4 1 MalT-like TPR region CARD_2 PF16739.5 PVD23048.1 - 0.00079 19.4 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 Caspase recruitment domain TPR_1 PF00515.28 PVD23048.1 - 0.0011 18.7 0.0 0.027 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PI3Ka PF00613.20 PVD23048.1 - 0.011 15.1 0.4 0.054 12.9 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TPR_2 PF07719.17 PVD23048.1 - 0.026 14.6 0.2 0.4 10.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23048.1 - 0.24 11.9 4.9 12 6.5 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF836 PF05768.14 PVD23048.1 - 0.37 11.2 2.2 0.95 9.9 0.0 3.0 3 1 0 3 3 3 0 Glutaredoxin-like domain (DUF836) CLP_protease PF00574.23 PVD23049.1 - 3.5e-81 271.4 0.1 4.4e-81 271.1 0.1 1.1 1 0 0 1 1 1 1 Clp protease Aminotran_1_2 PF00155.21 PVD23050.1 - 8.5e-18 64.7 0.0 1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PVD23050.1 - 1.1e-08 34.3 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Laminin_G_2 PF02210.24 PVD23051.1 - 9e-41 139.4 1.6 2.5e-14 53.9 0.2 3.5 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 PVD23051.1 - 2.8e-25 89.0 0.7 1.6e-11 44.6 0.0 3.5 3 1 0 3 3 3 3 Laminin G domain EGF PF00008.27 PVD23051.1 - 1.9e-05 24.9 22.1 6.9e-05 23.1 7.7 3.1 3 0 0 3 3 2 2 EGF-like domain hEGF PF12661.7 PVD23051.1 - 0.0097 16.5 5.4 0.0097 16.5 5.4 3.6 3 0 0 3 3 3 1 Human growth factor-like EGF DAG1 PF05454.11 PVD23051.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ninjurin PF04923.12 PVD23051.1 - 0.056 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Ninjurin Sialidase PF02973.16 PVD23051.1 - 0.1 12.1 0.4 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Sialidase, N-terminal domain Gemini_C4 PF01492.17 PVD23051.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Geminivirus C4 protein EphA2_TM PF14575.6 PVD23051.1 - 0.14 13.0 0.0 0.52 11.2 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PVD23051.1 - 0.26 11.1 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 SKG6 PF08693.10 PVD23051.1 - 0.81 9.1 4.4 1.5 8.3 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 PVD23051.1 - 7 6.7 5.1 5.6 7.0 3.4 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DOT1 PF08123.13 PVD23053.1 - 1.3e-73 246.9 0.0 2.5e-73 246.0 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 SNF2_N PF00176.23 PVD23054.1 - 2.7e-59 200.6 0.7 5.9e-59 199.5 0.7 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD23054.1 - 2.3e-17 63.3 0.0 7.9e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD23054.1 - 1.9e-11 44.3 0.0 8.7e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 PVD23054.1 - 1.2e-09 38.6 0.7 5.3e-09 36.5 0.4 2.0 2 0 0 2 2 2 1 Rad54 N terminal DEAD PF00270.29 PVD23054.1 - 1.6e-07 31.3 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PVD23054.1 - 0.00032 20.4 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 PVD23054.1 - 0.00033 19.9 1.7 0.00089 18.5 0.0 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DnaJ_C PF01556.18 PVD23055.1 - 1.3e-45 155.1 0.2 1.9e-45 154.6 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PVD23055.1 - 2.5e-28 98.0 2.0 4e-28 97.3 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain LRR_4 PF12799.7 PVD23056.1 - 1.5e-37 127.0 38.6 4.1e-06 27.0 2.7 9.4 8 1 1 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD23056.1 - 2.6e-36 123.2 35.6 4.4e-08 32.8 0.0 7.2 1 1 9 11 11 11 11 Leucine rich repeat PDZ PF00595.24 PVD23056.1 - 5.7e-16 58.6 0.2 1.1e-15 57.8 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD23056.1 - 7.5e-07 28.9 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD23056.1 - 6.4e-05 23.2 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 PVD23056.1 - 7.7e-05 22.7 0.0 1.2 9.2 0.0 3.4 2 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD23056.1 - 0.0014 18.9 30.5 25 5.9 0.1 11.3 12 0 0 12 12 12 0 Leucine Rich Repeat LRR_9 PF14580.6 PVD23056.1 - 0.0077 15.7 12.2 2.2 7.7 0.1 4.3 1 1 2 4 4 4 3 Leucine-rich repeat Ank_4 PF13637.6 PVD23057.1 - 4.8e-11 43.0 0.1 3.2e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD23057.1 - 1.7e-10 41.3 0.0 1.1e-05 25.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23057.1 - 4.1e-09 36.5 0.0 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD23057.1 - 1.7e-08 34.5 0.1 0.0036 17.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PVD23057.1 - 1.5e-05 25.0 0.1 2.2 9.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ntox25 PF15530.6 PVD23057.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 25 DUF908 PF06012.12 PVD23058.1 - 0.0065 15.9 1.0 0.011 15.2 1.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) 7TM_GPCR_Srw PF10324.9 PVD23059.1 - 1.1e-10 41.3 8.3 1.4e-10 41.0 8.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD23059.1 - 0.0016 17.8 7.2 0.0022 17.4 7.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NADHdeh_related PF10125.9 PVD23059.1 - 0.0082 15.5 1.4 0.014 14.8 1.4 1.4 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein Gaa1 PF04114.14 PVD23059.1 - 0.023 13.7 3.6 0.024 13.6 3.6 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF4282 PF14110.6 PVD23059.1 - 1 10.2 9.7 4 8.2 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) KORA PF16509.5 PVD23061.1 - 0.13 12.5 0.0 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Forkhead PF00250.18 PVD23064.1 - 6.2e-37 125.7 0.0 1.3e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Ank_2 PF12796.7 PVD23066.1 - 4.8e-23 81.6 0.6 3.1e-11 43.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD23066.1 - 8.2e-21 71.9 2.9 2e-05 24.6 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PVD23066.1 - 1.8e-19 69.8 1.4 5e-05 23.8 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD23066.1 - 3.1e-17 62.2 4.4 0.00078 19.8 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD23066.1 - 1.6e-15 56.9 2.4 3.1e-08 33.7 0.0 4.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DUF5098 PF17023.5 PVD23066.1 - 0.06 12.3 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) APH_6_hur PF04655.14 PVD23066.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Membralin PF09746.9 PVD23068.1 - 1.3e-164 547.8 0.9 2.2e-164 547.0 0.9 1.4 1 0 0 1 1 1 1 Tumour-associated protein PUL PF08324.11 PVD23069.1 - 6.4e-47 160.1 4.0 8.7e-47 159.7 4.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 PVD23069.1 - 3.7e-44 149.6 0.1 6.5e-44 148.8 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 PVD23069.1 - 1.3e-38 130.3 16.7 1.3e-06 29.0 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 PVD23069.1 - 1.4e-06 28.3 0.0 0.65 10.1 0.0 3.5 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region DNApol3-delta_C PF09115.10 PVD23069.1 - 0.095 13.2 5.1 1.1 9.8 0.5 2.7 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal HMG_box PF00505.19 PVD23071.1 - 0.00016 22.0 0.1 0.0005 20.4 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Patched PF02460.18 PVD23072.1 - 1.4e-132 443.5 10.8 1.8e-132 443.1 10.8 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD23072.1 - 1.7e-32 112.4 4.8 1.7e-32 112.4 4.8 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 PVD23072.1 - 0.0048 14.6 13.6 0.008 13.9 13.6 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family TGT PF01702.18 PVD23073.1 - 3.3e-66 223.8 0.0 4.1e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glutaredoxin PF00462.24 PVD23074.1 - 0.0051 17.0 0.2 0.011 15.9 0.1 1.7 1 1 1 2 2 2 1 Glutaredoxin DUF5587 PF17825.1 PVD23075.1 - 3.6e-16 57.8 4.1 3.6e-13 47.8 0.4 3.7 4 0 0 4 4 4 3 Family of unknown function (DUF5587) DUF5580 PF17743.1 PVD23076.1 - 1.5e-08 33.7 1.1 4.9e-08 32.0 0.4 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5580) FCD PF07729.12 PVD23076.1 - 0.034 14.6 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 FCD domain SUI1 PF01253.22 PVD23077.1 - 2.6e-17 63.1 0.1 5.4e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 PVD23077.1 - 8.2e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Lectin_C PF00059.21 PVD23078.1 - 1.4e-08 35.4 0.0 2.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain NAGLU PF05089.12 PVD23079.1 - 5.8e-136 452.8 4.7 9.8e-136 452.1 4.7 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 PVD23079.1 - 1.6e-74 250.8 1.0 2.4e-74 250.3 1.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 PVD23079.1 - 4.2e-20 71.3 0.0 8.2e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF1908 PF08926.11 PVD23080.1 - 3.1e-120 400.6 3.6 3.1e-120 400.6 3.6 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 PVD23080.1 - 5.7e-61 206.2 0.2 5.9e-59 199.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23080.1 - 2.9e-27 95.6 0.1 1.1e-26 93.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ_6 PF17820.1 PVD23080.1 - 1.4e-08 34.4 0.0 3.7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.30 PVD23080.1 - 3.8e-06 27.2 0.0 1.2e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.6 PVD23080.1 - 4.3e-06 26.9 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD23080.1 - 3.3e-05 24.2 0.0 7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 PVD23080.1 - 0.00081 19.4 0.0 0.062 13.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD23080.1 - 0.00094 18.6 1.1 0.0091 15.3 0.0 2.5 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 PVD23080.1 - 0.062 12.9 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PVD23080.1 - 0.066 12.0 1.1 0.15 10.8 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase HRDC PF00570.23 PVD23080.1 - 0.082 12.9 0.1 3.4 7.7 0.0 3.0 2 0 0 2 2 2 0 HRDC domain SAM_2 PF07647.17 PVD23080.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pyocin_S PF06958.12 PVD23080.1 - 6.5 7.3 6.5 1.2 9.6 1.1 2.6 2 1 0 2 2 1 0 S-type Pyocin Phosphodiest PF01663.22 PVD23081.1 - 2.9e-246 816.6 11.5 3.1e-83 280.3 1.3 3.2 3 0 0 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase Endonuclease_NS PF01223.23 PVD23081.1 - 9.1e-16 58.4 0.4 2.1e-05 24.4 0.0 5.1 4 1 0 4 4 4 3 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 PVD23081.1 - 8.4e-12 45.1 3.8 3.4e-07 30.0 0.1 4.5 3 3 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.18 PVD23081.1 - 2.5e-06 27.1 0.0 0.48 9.8 0.0 3.3 3 0 0 3 3 3 3 Metalloenzyme superfamily PglZ PF08665.12 PVD23081.1 - 3.1e-05 24.1 0.0 2 8.5 0.0 4.2 4 0 0 4 4 4 3 PglZ domain RNA_pol_Rpb4 PF03874.16 PVD23082.1 - 1.6e-27 96.3 4.3 2.1e-27 95.9 4.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 LMBR1 PF04791.16 PVD23083.1 - 4.8e-160 533.8 14.6 5.9e-160 533.5 14.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein LRR_6 PF13516.6 PVD23084.1 - 7.4e-23 78.6 10.5 0.013 15.5 0.0 8.5 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_1 PF00036.32 PVD23084.1 - 4.5e-11 41.5 2.8 0.0006 19.2 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PVD23084.1 - 6.3e-09 36.2 2.6 1.1e-08 35.4 0.5 2.5 3 0 0 3 3 3 1 EF-hand domain pair LRR_1 PF00560.33 PVD23084.1 - 1.9e-08 33.7 4.7 1.6 9.6 0.0 7.6 8 0 0 8 8 8 1 Leucine Rich Repeat EF-hand_6 PF13405.6 PVD23084.1 - 4.8e-07 29.2 2.1 0.011 15.5 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain LRR_8 PF13855.6 PVD23084.1 - 0.00065 19.4 10.6 0.011 15.4 0.3 4.9 4 2 1 5 5 5 2 Leucine rich repeat SPARC_Ca_bdg PF10591.9 PVD23084.1 - 0.015 15.6 1.0 0.23 11.8 0.2 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_4 PF12799.7 PVD23084.1 - 0.02 15.3 13.6 0.87 10.1 0.1 5.2 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 PVD23084.1 - 0.031 13.8 6.9 0.52 9.9 0.1 3.6 3 0 0 3 3 3 0 EF hand THB PF18362.1 PVD23084.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Tri-helix bundle domain EF-hand_8 PF13833.6 PVD23084.1 - 0.078 12.8 2.0 0.33 10.8 0.4 2.6 1 1 1 2 2 2 0 EF-hand domain pair MR_MLE_C PF13378.6 PVD23085.1 - 3.7e-56 190.2 0.0 5.8e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 PVD23085.1 - 3.3e-07 30.5 0.0 5.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 PVD23085.1 - 0.0014 17.9 0.0 0.0032 16.6 0.0 1.6 1 1 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DUF2742 PF10888.8 PVD23085.1 - 0.15 12.3 0.4 0.41 10.9 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2742) Strumpellin PF10266.9 PVD23086.1 - 0 1388.6 21.8 5.1e-225 749.7 5.4 3.0 1 1 2 3 3 3 3 Hereditary spastic paraplegia protein strumpellin PhoU_div PF01865.16 PVD23086.1 - 0.011 15.1 1.1 0.69 9.2 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF47 DUF3106 PF11304.8 PVD23086.1 - 0.05 14.1 4.5 0.28 11.7 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Rad17 PF03215.15 PVD23087.1 - 1.4e-18 67.5 0.2 6.3e-13 49.1 0.2 2.4 1 1 1 2 2 2 2 Rad17 P-loop domain AAA_assoc_2 PF16193.5 PVD23087.1 - 0.0035 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Glyco_hydro_31 PF01055.26 PVD23088.1 - 1.4e-134 449.7 2.5 1.8e-134 449.3 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PVD23088.1 - 1.6e-20 73.5 0.0 2.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 PVD23088.1 - 3e-05 23.8 0.1 3e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain EGF_2 PF07974.13 PVD23089.1 - 1.9e-07 31.3 52.4 0.012 15.9 4.9 4.4 3 1 1 4 4 4 3 EGF-like domain EGF PF00008.27 PVD23089.1 - 0.13 12.6 64.5 0.34 11.2 5.7 4.8 5 0 0 5 5 5 0 EGF-like domain SAP130_C PF16014.5 PVD23089.1 - 8 5.4 7.3 1.2 8.2 3.0 1.6 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Profilin PF00235.19 PVD23090.1 - 4.5e-26 91.6 0.0 5.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Profilin AAT PF03417.16 PVD23091.1 - 6.7e-30 104.5 0.0 1e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Profilin PF00235.19 PVD23092.1 - 3.9e-09 36.8 0.0 4.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Profilin PRKCSH-like PF12999.7 PVD23093.1 - 1.7e-42 145.2 9.3 1.7e-42 145.2 9.3 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 PVD23093.1 - 7.1e-27 94.0 0.4 1.6e-26 92.8 0.4 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PVD23093.1 - 1.1e-10 42.4 3.1 1.1e-10 42.4 3.1 2.9 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein EF-hand_1 PF00036.32 PVD23093.1 - 5.9e-05 22.3 0.3 0.038 13.6 0.1 2.8 1 1 1 2 2 2 2 EF hand Ldl_recept_a PF00057.18 PVD23093.1 - 0.0012 19.0 10.8 0.33 11.2 0.7 2.8 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A EF-hand_6 PF13405.6 PVD23093.1 - 0.0076 16.1 0.2 2.8 8.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 PVD23093.1 - 0.022 14.2 0.5 0.55 9.8 0.1 2.9 2 0 0 2 2 2 0 EF hand ExsD PF16806.5 PVD23093.1 - 0.1 12.5 2.8 0.16 11.8 2.8 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD Peptidase_M2 PF01401.18 PVD23094.1 - 8.2e-243 807.2 4.4 9.4e-243 807.0 4.4 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Arteri_nucleo PF01481.16 PVD23095.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein ASC PF00858.24 PVD23096.1 - 5.8e-16 58.5 0.0 5.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 PVD23097.1 - 5.4e-42 144.3 4.1 7e-42 143.9 4.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 PVD23098.1 - 2.3e-26 92.7 0.1 2.8e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SAM_1 PF00536.30 PVD23099.1 - 1.3e-07 31.9 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHD PF00628.29 PVD23099.1 - 6.5e-06 25.9 6.4 6.5e-06 25.9 6.4 2.4 2 1 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 PVD23099.1 - 0.00014 21.9 4.8 0.00014 21.9 4.8 2.1 1 1 1 2 2 2 1 PHD-finger SAM_PNT PF02198.16 PVD23099.1 - 0.0005 20.0 0.0 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 PVD23099.1 - 0.00065 19.8 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHD PF00628.29 PVD23100.1 - 6.7e-18 64.3 23.3 7.1e-12 45.0 7.0 2.6 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 PVD23100.1 - 6.5e-11 42.5 0.7 5.5e-10 39.5 0.1 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD23100.1 - 1.4e-05 25.1 0.8 4.4e-05 23.5 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD23100.1 - 8.6e-05 22.4 0.0 0.00051 20.0 0.0 2.3 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain PHD_2 PF13831.6 PVD23100.1 - 0.0023 17.5 13.9 0.0042 16.6 1.4 2.9 2 1 0 2 2 2 2 PHD-finger Linker_histone PF00538.19 PVD23100.1 - 0.01 16.2 0.0 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 linker histone H1 and H5 family C1_2 PF03107.16 PVD23100.1 - 2.5 8.5 16.9 4.4 7.7 2.1 2.9 2 0 0 2 2 2 0 C1 domain MIS13 PF08202.11 PVD23101.1 - 7.6e-09 35.3 6.9 1.3e-08 34.5 6.5 1.5 1 1 1 2 2 2 1 Mis12-Mtw1 protein family TACC_C PF05010.14 PVD23101.1 - 0.021 14.6 2.2 0.026 14.3 1.3 1.5 2 0 0 2 2 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal OmpH PF03938.14 PVD23101.1 - 0.022 15.1 1.9 0.036 14.4 1.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 PVD23101.1 - 0.047 13.9 4.1 0.12 12.6 4.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 PVD23101.1 - 0.11 10.4 4.2 0.088 10.7 1.0 1.7 1 1 0 1 1 1 0 Prominin DELLA PF12041.8 PVD23101.1 - 0.15 12.0 1.4 4.9 7.1 0.0 3.1 3 1 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF1640 PF07798.11 PVD23101.1 - 0.19 11.7 4.8 0.18 11.8 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) KfrA_N PF11740.8 PVD23101.1 - 0.26 12.0 3.1 0.46 11.2 0.9 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF948 PF06103.11 PVD23101.1 - 0.54 10.5 6.8 1.2e+02 3.0 6.8 3.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 PVD23101.1 - 0.61 10.4 5.6 2.2 8.7 2.3 3.0 2 1 0 2 2 2 0 Tup N-terminal TMPIT PF07851.13 PVD23101.1 - 0.63 9.2 3.0 2.1 7.5 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein GIT_CC PF16559.5 PVD23101.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.8 4 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4404 PF14357.6 PVD23101.1 - 1.3 9.8 6.1 17 6.1 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Jnk-SapK_ap_N PF09744.9 PVD23101.1 - 1.4 9.1 8.0 0.63 10.3 3.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V-SNARE PF05008.15 PVD23101.1 - 2.4 8.6 9.3 0.44 11.0 1.1 3.3 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.9 PVD23101.1 - 4.4 7.7 8.5 8.5 6.8 0.4 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reeler PF02014.16 PVD23102.1 - 1.3e-49 168.2 13.5 6.8e-26 91.5 0.8 2.6 3 0 0 3 3 3 2 Reeler domain Reeler PF02014.16 PVD23104.1 - 7.2e-10 39.7 0.1 1.1e-09 39.1 0.1 1.3 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 PVD23105.1 - 2.5e-26 93.0 2.3 4.4e-26 92.1 2.3 1.4 1 0 0 1 1 1 1 Reeler domain DUF2946 PF11162.8 PVD23105.1 - 0.067 13.9 1.3 0.099 13.3 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Reeler PF02014.16 PVD23106.1 - 4.5e-15 56.5 0.2 5.6e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 Reeler domain Flo11 PF10182.9 PVD23106.1 - 0.01 16.0 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 0 Flo11 domain fn3 PF00041.21 PVD23106.1 - 0.016 15.5 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 Fibronectin type III domain DUF2946 PF11162.8 PVD23106.1 - 0.022 15.4 0.9 0.034 14.8 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Reeler PF02014.16 PVD23107.1 - 8.7e-29 100.9 3.0 1.2e-28 100.4 3.0 1.2 1 0 0 1 1 1 1 Reeler domain Flo11 PF10182.9 PVD23107.1 - 0.00089 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Flo11 domain DUF2946 PF11162.8 PVD23107.1 - 0.013 16.1 0.5 0.031 15.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Reeler PF02014.16 PVD23108.1 - 4.9e-14 53.2 0.0 5.6e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Reeler domain Amidase PF01425.21 PVD23109.1 - 3.8e-94 316.2 0.0 1.3e-77 261.7 0.0 2.1 1 1 1 2 2 2 2 Amidase Zip PF02535.22 PVD23110.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CP2 PF04516.15 PVD23112.1 - 1.8e-51 174.7 0.5 3.3e-51 173.8 0.0 1.6 2 0 0 2 2 2 1 CP2 transcription factor Mago_nashi PF02792.14 PVD23113.1 - 1.7e-27 96.3 0.1 2e-27 96.1 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Mago_nashi PF02792.14 PVD23114.1 - 2.5e-44 150.9 0.0 2.7e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein WD40 PF00400.32 PVD23115.1 - 3.4e-29 100.5 21.4 4.1e-05 24.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23115.1 - 1.4e-11 44.6 0.2 0.00068 19.9 0.0 4.2 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD23115.1 - 0.00057 19.3 1.5 0.0065 15.8 1.6 2.1 1 1 0 1 1 1 1 WD40-like domain eIF2A PF08662.11 PVD23115.1 - 0.002 18.0 0.0 0.11 12.3 0.0 2.9 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ig_3 PF13927.6 PVD23116.1 - 1.5e-22 79.9 0.2 9.7e-14 51.7 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD23116.1 - 2.3e-19 69.3 0.0 2.5e-13 49.9 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD23116.1 - 7.7e-17 61.4 0.1 9.5e-11 41.9 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD23116.1 - 8.3e-11 41.9 0.1 0.00037 20.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD23116.1 - 3.9e-09 36.6 0.3 1.9e-06 28.0 0.3 3.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD23116.1 - 1.7e-06 28.0 0.1 0.002 18.1 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD23116.1 - 0.0017 17.8 0.3 0.0057 16.2 0.0 2.0 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 PVD23116.1 - 0.0074 16.6 0.1 0.9 10.0 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Pkinase_Tyr PF07714.17 PVD23117.1 - 1.9e-90 302.6 0.0 2.5e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD23117.1 - 5.8e-37 127.5 0.0 3.9e-22 78.9 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Kringle PF00051.18 PVD23117.1 - 1.9e-24 85.7 4.7 4.4e-24 84.6 4.7 1.7 1 0 0 1 1 1 1 Kringle domain DUF1189 PF06691.11 PVD23117.1 - 0.006 16.2 0.1 0.0089 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1189) Yip1 PF04893.17 PVD23117.1 - 0.019 14.7 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain HMG_CoA_synt_C PF08540.10 PVD23118.1 - 3.9e-84 282.6 1.0 4.7e-81 272.5 1.0 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 PVD23118.1 - 6.9e-71 237.7 6.6 4.6e-36 124.3 0.0 2.4 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 PVD23118.1 - 0.071 13.0 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Alpha-amylase_C PF02806.18 PVD23119.1 - 5.4e-15 55.6 0.0 1.4e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 PVD23119.1 - 1.3e-12 48.0 0.0 3.2e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PVD23120.1 - 4.2e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 PVD23120.1 - 9.8e-12 45.1 0.0 3.5e-10 40.0 0.0 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_31 PF01055.26 PVD23121.1 - 2.5e-257 854.1 8.1 1.6e-132 442.9 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PVD23121.1 - 1.3e-48 164.0 1.3 5.3e-27 94.3 0.0 3.0 3 0 0 3 3 3 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 PVD23121.1 - 5.4e-07 29.4 0.8 5.4e-07 29.4 0.8 2.3 3 0 0 3 3 3 1 Trefoil (P-type) domain DUF5110 PF17137.4 PVD23121.1 - 0.00075 19.7 2.0 0.0025 18.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5110) CR6_interact PF10147.9 PVD23122.1 - 1.3e-48 165.5 28.0 1.5e-48 165.2 28.0 1.0 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4407 PF14362.6 PVD23122.1 - 0.83 9.0 11.6 0.99 8.7 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PSII_Pbs27 PF13326.6 PVD23122.1 - 1 9.7 9.5 0.15 12.4 3.3 2.4 1 1 1 2 2 2 0 Photosystem II Pbs27 AbiH PF14253.6 PVD23122.1 - 3.8 7.3 9.6 4.9 6.9 9.6 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Mitoc_mL59 PF18126.1 PVD23122.1 - 6 7.2 19.5 0.4 11.0 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 Joubert PF15392.6 PVD23123.1 - 4.4e-06 26.7 36.4 4.4e-06 26.7 36.4 6.1 3 1 1 4 4 4 1 Joubert syndrome-associated RNB PF00773.19 PVD23125.1 - 1.8e-06 27.6 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNB domain RNB PF00773.19 PVD23126.1 - 7.6e-12 45.2 0.6 4.5e-11 42.7 0.6 1.8 1 1 0 1 1 1 1 RNB domain AAA_11 PF13086.6 PVD23127.1 - 2.5e-43 148.8 0.3 5.3e-43 147.7 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 PVD23127.1 - 3.5e-29 101.9 1.9 7.8e-23 81.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 PVD23127.1 - 1.4e-10 41.3 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PVD23127.1 - 7.5e-09 36.1 0.2 3.5e-08 33.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PVD23127.1 - 3.7e-08 33.4 0.8 4.3e-07 29.9 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 PVD23127.1 - 7e-06 25.6 0.1 1.3e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 PVD23127.1 - 7.4e-05 22.5 0.9 0.00064 19.5 0.9 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 PVD23127.1 - 0.00014 21.2 4.5 0.046 13.0 0.0 3.4 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 PVD23127.1 - 0.005 17.1 0.0 0.018 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD23127.1 - 0.045 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 PVD23127.1 - 0.11 12.0 2.6 0.59 9.6 0.1 2.7 1 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DUF1722 PF08349.11 PVD23128.1 - 0.017 15.4 0.2 0.039 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) HEPN_Apea PF18739.1 PVD23128.1 - 0.069 13.6 0.3 0.26 11.7 0.2 2.0 2 0 0 2 2 2 0 Apea-like HEPN DUF4404 PF14357.6 PVD23128.1 - 1.2 9.8 4.7 3.3 8.4 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF2076 PF09849.9 PVD23128.1 - 4 7.4 7.9 0.23 11.5 1.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RNB PF00773.19 PVD23129.1 - 3.1e-61 207.5 0.1 1.3e-45 156.2 0.0 2.3 1 1 1 2 2 2 2 RNB domain AAA_12 PF13087.6 PVD23129.1 - 6e-46 156.6 0.0 9.9e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD23129.1 - 7.2e-41 140.7 0.0 1.6e-40 139.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD23129.1 - 1.8e-09 37.6 0.0 0.00054 19.7 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PVD23129.1 - 9.1e-08 32.6 0.0 8.1e-07 29.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PVD23129.1 - 0.00017 21.0 0.4 0.069 12.4 0.0 2.8 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 PVD23129.1 - 0.0025 17.6 0.2 0.014 15.2 0.2 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 PVD23129.1 - 0.016 14.6 0.0 0.043 13.2 0.0 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 PVD23129.1 - 0.018 15.3 0.0 0.38 11.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 PVD23129.1 - 0.027 14.2 0.2 5.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase OB_Dis3 PF17849.1 PVD23129.1 - 0.068 13.2 0.2 0.42 10.7 0.2 2.3 1 1 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) UvrD-helicase PF00580.21 PVD23129.1 - 0.079 12.5 0.1 13 5.1 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 PVD23129.1 - 0.079 13.0 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNB PF00773.19 PVD23130.1 - 4.5e-74 249.7 0.6 1.9e-73 247.6 0.0 2.4 2 1 0 2 2 2 1 RNB domain AAA_12 PF13087.6 PVD23130.1 - 1.5e-40 139.0 0.0 3.2e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD23130.1 - 2.9e-29 102.7 0.0 2.9e-29 102.7 0.0 2.8 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 PVD23130.1 - 0.00027 20.8 0.2 0.58 9.9 0.1 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 PVD23130.1 - 0.00081 19.2 0.0 0.0079 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 PVD23130.1 - 0.0098 15.3 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain OB_Dis3 PF17849.1 PVD23130.1 - 0.028 14.5 0.8 0.16 12.0 0.2 2.5 2 1 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) AAA_19 PF13245.6 PVD23130.1 - 0.037 14.3 0.0 0.32 11.3 0.0 2.5 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 PVD23130.1 - 0.038 13.8 0.2 0.24 11.2 0.2 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 PVD23131.1 - 0.019 14.3 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF1722 PF08349.11 PVD23131.1 - 0.087 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) RRP36 PF06102.12 PVD23131.1 - 0.1 12.6 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF2203 PF09969.9 PVD23131.1 - 0.14 12.8 1.4 1 10.1 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribonuc_2-5A PF06479.12 PVD23131.1 - 0.5 10.5 5.1 2.9 8.1 2.2 2.3 1 1 1 2 2 2 0 Ribonuclease 2-5A RNB PF00773.19 PVD23132.1 - 3.3e-75 253.4 0.0 3e-74 250.3 0.0 2.1 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PVD23132.1 - 0.0027 17.7 0.8 0.048 13.7 0.3 2.9 2 1 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) DUF4618 PF15397.6 PVD23132.1 - 0.051 13.0 0.8 1.3 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) RNB PF00773.19 PVD23134.1 - 4.6e-62 210.2 3.4 1e-48 166.4 1.0 3.1 1 1 1 2 2 2 2 RNB domain AAA_11 PF13086.6 PVD23134.1 - 5.1e-15 56.0 1.5 2.7e-11 43.8 0.4 2.8 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 PVD23134.1 - 4.6e-11 42.7 0.0 9.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD23134.1 - 0.00019 21.2 0.0 0.008 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PVD23134.1 - 0.0039 17.0 0.0 0.54 9.9 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 PVD23134.1 - 0.044 14.1 0.0 1 9.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain OB_Dis3 PF17849.1 PVD23134.1 - 0.12 12.4 2.1 0.44 10.6 0.2 2.9 3 1 0 3 3 3 0 Dis3-like cold-shock domain 2 (CSD2) AAA_12 PF13087.6 PVD23135.1 - 5.5e-47 160.0 0.0 8.1e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD23135.1 - 8.4e-21 74.9 0.7 3.7e-20 72.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 PVD23135.1 - 6.8e-06 25.7 0.0 0.0012 18.3 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PVD23135.1 - 8.2e-06 25.7 0.3 0.042 13.6 0.1 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PVD23135.1 - 6.9e-05 22.6 0.8 0.00057 19.7 0.8 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PVD23135.1 - 0.00064 19.5 0.0 0.0022 17.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD23135.1 - 0.09 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 PVD23136.1 - 0.04 14.6 3.4 0.04 14.6 3.4 2.4 2 1 1 3 3 3 0 Occludin homology domain DASH_Hsk3 PF08227.11 PVD23136.1 - 0.069 13.5 0.3 0.069 13.5 0.3 1.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like SlyX PF04102.12 PVD23136.1 - 0.15 12.7 16.0 0.15 12.7 1.3 4.2 1 1 3 4 4 4 0 SlyX HIP1_clath_bdg PF16515.5 PVD23136.1 - 0.5 11.0 23.0 3.2 8.4 9.5 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 PVD23136.1 - 0.65 8.8 26.8 0.61 8.9 10.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 PVD23136.1 - 0.68 10.4 22.6 0.24 11.8 17.7 2.1 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 PVD23136.1 - 0.69 9.9 16.6 2 8.4 8.0 2.2 1 1 0 2 2 2 0 Laminin Domain II CTNNB1_binding PF08347.11 PVD23136.1 - 0.83 9.8 4.2 1.3 9.2 4.2 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Baculo_PEP_C PF04513.12 PVD23136.1 - 3.7 7.6 5.5 8.5 6.4 0.6 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KIP1 PF07765.12 PVD23136.1 - 6 7.1 8.7 0.34 11.0 1.1 2.7 1 1 0 3 3 3 0 KIP1-like protein AAA_13 PF13166.6 PVD23136.1 - 6.1 5.3 16.9 1 7.9 8.8 1.9 1 1 1 2 2 2 0 AAA domain Clathrin PF00637.20 PVD23138.1 - 1e-19 70.8 25.2 8.5e-07 28.9 0.1 11.5 7 3 3 11 11 11 5 Region in Clathrin and VPS WD40 PF00400.32 PVD23138.1 - 6.3e-13 49.0 1.1 0.29 12.1 0.0 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23138.1 - 3.8e-11 43.1 0.9 0.059 13.7 0.0 6.3 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 PVD23138.1 - 4.9e-06 26.2 27.6 2.2 8.5 0.3 12.0 11 3 1 12 12 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD23138.1 - 0.00061 20.4 33.1 13 6.9 0.1 13.8 14 3 1 15 15 15 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 PVD23138.1 - 0.0013 17.9 10.3 0.011 14.8 0.0 5.7 7 1 1 8 8 8 1 Coatomer WD associated region RPN7 PF10602.9 PVD23138.1 - 0.036 13.8 22.1 0.3 10.8 1.0 6.5 3 2 1 6 6 6 0 26S proteasome subunit RPN7 Frtz PF11768.8 PVD23138.1 - 0.064 11.6 0.1 0.34 9.2 0.0 2.3 3 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_2 PF07719.17 PVD23138.1 - 0.12 12.5 50.7 0.31 11.3 0.9 13.0 14 0 0 14 14 13 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD23138.1 - 0.22 11.8 20.6 4.5 7.6 0.1 8.1 6 3 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PVD23138.1 - 0.26 11.6 35.8 0.12 12.7 1.2 11.2 12 1 1 13 13 13 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23138.1 - 0.31 10.9 38.2 0.33 10.8 1.2 11.0 13 1 1 14 14 12 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23138.1 - 0.61 10.6 0.0 0.61 10.6 0.0 9.9 9 4 2 11 11 11 0 Tetratricopeptide repeat Sec16_C PF12931.7 PVD23138.1 - 1.3 8.6 7.0 1.6 8.3 0.1 3.9 3 1 1 4 4 4 0 Sec23-binding domain of Sec16 Cytochrom_B562 PF07361.11 PVD23138.1 - 2 9.1 7.7 0.91 10.2 0.3 3.5 3 1 0 3 3 2 0 Cytochrome b562 TPR_12 PF13424.6 PVD23138.1 - 3.4 8.0 38.4 4.7 7.6 0.4 11.7 10 4 4 14 14 14 0 Tetratricopeptide repeat PPR PF01535.20 PVD23138.1 - 5.9 7.4 19.1 17 6.0 0.1 9.2 10 2 2 12 12 11 0 PPR repeat Ribosomal_S21e PF01249.18 PVD23139.1 - 6.5e-37 125.5 0.4 7.1e-37 125.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CofC PF01983.16 PVD23140.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like DERM PF14704.6 PVD23141.1 - 1.4e-11 45.1 0.2 1.5e-11 45.0 0.2 1.0 1 0 0 1 1 1 1 Dermatopontin Gly_transf_sug PF04488.15 PVD23142.1 - 2.1e-09 37.9 0.0 4.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD23142.1 - 8.1e-05 22.1 0.2 0.0001 21.8 0.2 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD23142.1 - 0.047 13.0 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PAN_1 PF00024.26 PVD23143.1 - 3.9e-30 103.7 36.5 6.7e-09 35.6 2.5 5.7 4 1 1 5 5 5 5 PAN domain PAN_4 PF14295.6 PVD23143.1 - 1.7e-06 27.8 37.6 0.0024 17.8 1.0 5.9 5 0 0 5 5 5 5 PAN domain PAN_1 PF00024.26 PVD23144.1 - 8.3e-75 246.8 107.2 3.5e-08 33.3 0.5 15.5 13 1 2 15 15 15 15 PAN domain Podoplanin PF05808.11 PVD23144.1 - 5.8e-06 26.5 0.2 3.1 7.9 0.0 3.4 3 0 0 3 3 3 3 Podoplanin TMEM223 PF14640.6 PVD23144.1 - 4.2e-05 23.8 0.0 3.4 7.8 0.0 3.9 4 0 0 4 4 4 2 Transmembrane protein 223 Ependymin PF00811.18 PVD23144.1 - 0.00054 20.2 0.0 4.9 7.4 0.0 3.7 3 0 0 3 3 3 2 Ependymin PAN_4 PF14295.6 PVD23144.1 - 0.0034 17.3 1.9 0.0034 17.3 1.9 15.6 15 0 0 15 15 15 8 PAN domain DUF357 PF04010.13 PVD23144.1 - 0.17 12.0 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF357) YejG PF13989.6 PVD23144.1 - 0.17 12.3 0.0 0.48 10.9 0.0 1.7 1 0 0 1 1 1 0 YejG-like protein Spore_YtrH PF14034.6 PVD23144.1 - 0.26 11.5 10.6 0.84 9.8 0.0 3.8 3 1 1 4 4 4 0 Sporulation protein YtrH BPD_transp_2 PF02653.16 PVD23144.1 - 0.46 9.6 1.8 0.55 9.4 0.1 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component PUCC PF03209.15 PVD23144.1 - 1.2 8.1 2.2 56 2.6 0.2 2.9 3 0 0 3 3 3 0 PUCC protein DUF868 PF05910.12 PVD23145.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Coiled-coil_56 PF09813.9 PVD23146.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Dcc1 PF09724.9 PVD23147.1 - 4.9e-92 308.8 3.3 5.8e-92 308.5 3.3 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DEP PF00610.21 PVD23148.1 - 1.5e-28 98.7 6.3 1.2e-17 63.8 1.8 2.2 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDP-OH_P_transf PF01066.21 PVD23149.1 - 1.6e-15 57.6 0.0 1.6e-15 57.6 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase XendoU PF09412.10 PVD23150.1 - 1.4e-75 253.9 1.2 1.7e-75 253.7 1.2 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU C8 PF08742.11 PVD23151.1 - 3.5e-06 27.4 3.4 3.5e-06 27.4 3.4 2.4 1 1 1 2 2 2 1 C8 domain DUF1943 PF09172.11 PVD23152.1 - 4e-26 92.0 0.0 9.7e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 PVD23152.1 - 0.016 15.5 0.0 0.099 13.0 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1081) Vitellogenin_N PF01347.22 PVD23153.1 - 1.9e-21 76.2 0.0 1e-12 47.3 0.1 2.8 2 1 0 2 2 2 2 Lipoprotein amino terminal region Y_phosphatase PF00102.27 PVD23154.1 - 2.8e-99 331.5 3.1 4.6e-58 196.6 1.7 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 PVD23154.1 - 6.2e-08 32.5 0.9 4.7e-06 26.5 0.1 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Pex24p PF06398.11 PVD23155.1 - 0.46 9.4 0.6 0.43 9.5 0.6 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4191 PF13829.6 PVD23155.1 - 3.7 6.8 9.0 5.3 6.3 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tmemb_9 PF05434.11 PVD23155.1 - 5.4 6.9 12.1 8.4 6.3 12.1 1.3 1 0 0 1 1 1 0 TMEM9 ABC2_membrane_3 PF12698.7 PVD23156.1 - 4.2e-56 190.5 36.9 3.7e-39 134.8 18.1 3.5 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 PVD23156.1 - 6.1e-56 188.7 0.0 1.3e-28 100.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PVD23156.1 - 7.9e-22 78.4 0.1 1.3e-07 31.7 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PVD23156.1 - 0.00014 21.7 0.0 2 8.0 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 PVD23156.1 - 0.00022 21.8 5.9 0.0051 17.3 0.7 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PVD23156.1 - 0.0069 16.1 0.7 0.24 11.2 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 PVD23156.1 - 0.028 14.1 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PVD23156.1 - 0.036 14.0 0.3 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 PVD23156.1 - 0.14 12.4 0.0 49 4.3 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 PVD23156.1 - 0.17 11.5 4.3 5 6.7 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CPL PF08144.11 PVD23157.1 - 9.1e-36 123.3 0.1 9.1e-36 123.3 0.1 4.0 5 0 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 PVD23157.1 - 0.00012 21.6 1.2 0.0028 17.3 0.4 3.4 2 0 0 2 2 2 1 Pumilio-family RNA binding repeat Herpes_IE2_3 PF03361.14 PVD23157.1 - 0.073 12.9 0.5 0.82 9.5 0.1 2.7 2 1 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 ADK PF00406.22 PVD23158.1 - 4.1e-49 166.6 0.0 4.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PVD23158.1 - 7.4e-22 78.2 0.2 1.8e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PVD23158.1 - 2.8e-17 62.4 0.0 4.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 PVD23158.1 - 2.5e-08 34.5 0.0 4.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD23158.1 - 7e-05 23.0 0.0 0.00014 22.0 0.0 1.7 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 PVD23158.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 PVD23158.1 - 0.0043 17.5 0.0 0.007 16.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PVD23158.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 PVD23158.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 PVD23158.1 - 0.085 12.7 0.0 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 PVD23158.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PVD23158.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PVD23158.1 - 0.21 11.5 0.3 0.49 10.3 0.3 1.7 1 1 0 1 1 1 0 NACHT domain Ank_2 PF12796.7 PVD23159.1 - 2.9e-68 226.4 22.8 8.2e-22 77.6 0.9 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD23159.1 - 3e-45 152.0 10.3 3.7e-14 52.9 0.1 7.4 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23159.1 - 3.1e-44 143.9 8.6 7.8e-06 25.9 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 PVD23159.1 - 8.9e-44 146.1 15.7 2.6e-08 33.9 0.3 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 PVD23159.1 - 2.7e-35 120.0 9.4 6.6e-10 39.0 0.3 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD23159.1 - 6.4e-05 23.2 0.2 0.00013 22.3 0.2 1.5 1 0 0 1 1 1 1 SOCS box DUF2520 PF10728.9 PVD23159.1 - 0.00019 21.2 0.7 0.59 9.9 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF2520) G-patch PF01585.23 PVD23160.1 - 8.1e-09 35.2 2.9 1.5e-08 34.4 2.9 1.5 1 0 0 1 1 1 1 G-patch domain HEAT_2 PF13646.6 PVD23161.1 - 6.9e-28 96.9 3.9 2.4e-11 43.9 0.0 4.0 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 PVD23161.1 - 1.7e-27 93.3 1.3 0.00092 19.7 0.0 6.8 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 PVD23161.1 - 8.2e-11 41.2 3.2 0.2 12.0 0.1 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 PVD23161.1 - 0.0023 18.4 5.5 16 6.1 0.4 5.3 3 2 2 5 5 5 2 HEAT-like repeat Arm PF00514.23 PVD23161.1 - 0.0083 16.1 0.7 11 6.2 0.1 4.1 3 1 2 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3083 PF11281.8 PVD23161.1 - 0.024 14.0 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Cnd1 PF12717.7 PVD23161.1 - 0.056 13.5 1.4 2.9 7.9 0.4 3.3 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PC_rep PF01851.22 PVD23161.1 - 0.14 12.7 0.0 6.9 7.3 0.0 2.9 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Cpn60_TCP1 PF00118.24 PVD23162.1 - 1e-22 80.4 0.4 6.3e-13 48.2 0.0 2.7 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family C9orf72-like PF15019.6 PVD23163.1 - 0.00022 20.9 0.1 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 C9orf72-like protein family C9orf72-like PF15019.6 PVD23164.1 - 4.2e-30 105.1 0.5 5.9e-30 104.6 0.5 1.2 1 0 0 1 1 1 1 C9orf72-like protein family DHO_dh PF01180.21 PVD23165.1 - 2.3e-35 122.2 0.0 7e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 PVD23165.1 - 6.7e-32 109.6 0.3 1.2e-31 108.8 0.3 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 PVD23165.1 - 6e-09 35.5 0.0 3.2e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 PVD23165.1 - 2.5e-07 30.1 0.0 6.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyr_redox_3 PF13738.6 PVD23165.1 - 3.4e-05 23.3 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD23165.1 - 4e-05 23.8 0.4 0.00018 21.7 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PVD23165.1 - 7.5e-05 23.2 0.0 0.09 13.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 PVD23165.1 - 0.041 13.9 0.0 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF678 PF05077.12 PVD23165.1 - 0.42 10.8 3.9 1.2 9.3 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF678) DUF5561 PF17716.1 PVD23167.1 - 1.7e-64 217.5 2.0 2.3e-64 217.1 2.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5561) MIG-14_Wnt-bd PF06664.12 PVD23168.1 - 8.1e-91 304.3 22.0 9.7e-91 304.0 22.0 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2312 PF10073.9 PVD23169.1 - 7.4e-05 22.3 1.2 7.4e-05 22.3 1.2 2.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2312) DUF4795 PF16043.5 PVD23169.1 - 0.0017 18.0 2.9 0.0017 18.0 2.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) DUF3486 PF11985.8 PVD23169.1 - 0.0081 16.6 2.6 0.01 16.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) Paf67 PF10255.9 PVD23169.1 - 0.011 14.7 4.1 0.012 14.7 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Lyase_8_N PF08124.11 PVD23169.1 - 0.03 13.2 1.9 0.036 13.0 1.9 1.2 1 1 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain FAD-SLDH PF12318.8 PVD23169.1 - 0.031 14.3 3.0 0.091 12.8 0.1 2.0 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase TetR_C_34 PF17929.1 PVD23169.1 - 0.048 13.8 0.2 0.087 12.9 0.1 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ACP_PD PF04336.12 PVD23169.1 - 0.059 13.8 7.4 9.4 6.7 7.4 3.1 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Ku_C PF03730.14 PVD23169.1 - 0.074 13.8 7.3 0.15 12.8 2.8 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Prominin PF05478.11 PVD23169.1 - 0.078 10.9 3.9 0.085 10.8 3.9 1.0 1 0 0 1 1 1 0 Prominin Phasin PF05597.11 PVD23169.1 - 0.08 12.9 3.2 0.14 12.2 3.2 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4164 PF13747.6 PVD23169.1 - 0.087 13.1 3.5 2.6 8.4 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) YtxH PF12732.7 PVD23169.1 - 0.2 12.2 2.4 5.8 7.5 2.4 2.2 1 1 0 1 1 1 0 YtxH-like protein Exonuc_VII_L PF02601.15 PVD23169.1 - 0.33 10.5 5.7 0.4 10.2 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.8 PVD23169.1 - 0.35 11.2 12.4 0.84 10.0 12.4 1.6 1 1 0 1 1 1 0 YlqD protein FUSC-like PF12805.7 PVD23169.1 - 0.55 9.3 5.0 3.7 6.5 1.1 2.0 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS DUF1640 PF07798.11 PVD23169.1 - 0.78 9.8 11.3 0.2 11.7 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DASH_Dad4 PF08650.10 PVD23169.1 - 0.93 9.5 5.4 2.4 8.2 0.8 2.7 1 1 1 2 2 2 0 DASH complex subunit Dad4 XhlA PF10779.9 PVD23169.1 - 1.6 9.0 5.9 8.8 6.6 0.1 2.9 2 1 1 3 3 3 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 PVD23169.1 - 2.5 8.4 12.4 0.37 11.1 3.4 2.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain ZapB PF06005.12 PVD23169.1 - 4.1 7.9 11.9 0.46 11.0 5.5 2.1 1 1 1 2 2 2 0 Cell division protein ZapB SH3_2 PF07653.17 PVD23170.1 - 0.00045 19.8 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Cellulose_synt PF03552.14 PVD23170.1 - 5.8 5.3 5.0 9.1 4.6 5.0 1.2 1 0 0 1 1 1 0 Cellulose synthase MFS_1 PF07690.16 PVD23171.1 - 3e-48 164.5 27.1 3e-48 164.5 27.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 PVD23172.1 - 4.2e-25 87.9 35.4 1.1e-12 48.1 14.9 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Pox_A14 PF05767.12 PVD23172.1 - 0.045 13.9 1.7 0.16 12.1 0.3 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PIRT PF15099.6 PVD23172.1 - 4.3 6.9 8.7 2.8 7.5 0.6 2.7 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family LTV PF04180.14 PVD23173.1 - 4.3e-44 151.8 31.5 3e-43 149.0 31.5 2.0 1 1 0 1 1 1 1 Low temperature viability protein DP-EP PF08985.11 PVD23173.1 - 0.11 12.7 0.7 0.29 11.3 0.7 1.7 1 0 0 1 1 1 0 DP-EP family TPT PF03151.16 PVD23174.1 - 1.8e-09 37.4 8.6 1.6e-08 34.3 2.7 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family ELM2 PF01448.24 PVD23175.1 - 4.9e-09 36.8 0.1 1.3e-08 35.5 0.1 1.8 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 PVD23175.1 - 0.00071 19.7 0.2 0.0014 18.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PVD23175.1 - 0.056 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Myb DNA-binding like ACTL7A_N PF16840.5 PVD23176.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus DUF896 PF05979.12 PVD23176.1 - 0.027 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) WD40 PF00400.32 PVD23177.1 - 4.6e-12 46.3 5.4 0.00039 21.2 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23177.1 - 9.9e-07 29.0 0.2 4.1 7.8 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 PVD23177.1 - 0.0051 15.8 0.1 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PI3K_1B_p101 PF10486.9 PVD23177.1 - 0.23 9.2 7.4 0.32 8.7 7.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Baculo_PEP_C PF04513.12 PVD23178.1 - 0.0035 17.4 38.3 0.067 13.2 14.6 4.4 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 PVD23178.1 - 0.0094 14.9 30.7 0.27 10.1 8.4 3.9 1 1 3 4 4 4 3 Spc7 kinetochore protein Osmo_CC PF08946.10 PVD23178.1 - 0.0099 16.1 0.9 29 5.0 0.0 4.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DivIC PF04977.15 PVD23178.1 - 0.012 15.3 12.8 0.17 11.6 0.1 5.2 5 0 0 5 5 5 0 Septum formation initiator CENP-Q PF13094.6 PVD23178.1 - 0.022 15.0 21.9 0.029 14.6 10.0 3.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.9 PVD23178.1 - 0.027 14.8 29.3 0.57 10.5 2.9 5.3 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP_C PF03836.15 PVD23178.1 - 0.047 13.8 22.2 0.17 12.0 4.7 4.1 2 1 1 4 4 4 0 RasGAP C-terminus Occludin_ELL PF07303.13 PVD23178.1 - 0.063 14.0 15.8 0.43 11.3 0.2 5.4 1 1 4 5 5 5 0 Occludin homology domain DUF4201 PF13870.6 PVD23178.1 - 0.086 12.6 20.4 0.38 10.5 5.5 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) ACDC PF14733.6 PVD23178.1 - 0.1 12.9 1.5 4.1 7.8 0.2 3.0 2 0 0 2 2 2 0 AP2-coincident C-terminal PI3K_P85_iSH2 PF16454.5 PVD23178.1 - 0.18 11.4 16.6 0.23 11.0 0.8 3.7 2 2 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Laminin_II PF06009.12 PVD23178.1 - 0.27 11.3 32.1 1.7 8.7 2.5 4.4 1 1 2 4 4 4 0 Laminin Domain II FliD_C PF07195.12 PVD23178.1 - 0.33 10.3 25.5 0.17 11.3 13.3 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.17 PVD23178.1 - 0.43 10.5 18.0 0.57 10.1 0.3 4.4 3 1 1 4 4 4 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 PVD23178.1 - 0.51 10.4 32.4 0.4 10.7 8.8 4.8 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PVD23178.1 - 0.57 10.6 23.2 1.2 9.6 0.6 6.1 5 1 1 6 6 5 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 PVD23178.1 - 0.6 10.2 27.9 0.071 13.2 0.7 4.5 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PVD23178.1 - 0.6 9.4 30.7 0.34 10.2 2.2 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) DUF1515 PF07439.11 PVD23178.1 - 0.67 10.0 8.8 8.5 6.5 0.1 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) SlyX PF04102.12 PVD23178.1 - 0.69 10.6 29.2 1.2 9.8 3.0 6.4 5 2 2 7 7 7 0 SlyX CLZ PF16526.5 PVD23178.1 - 0.75 10.2 21.3 0.67 10.4 0.6 5.6 4 1 2 6 6 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 PVD23178.1 - 0.78 9.8 28.5 0.32 11.0 3.5 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PVD23178.1 - 0.9 10.0 29.7 0.37 11.3 1.2 5.2 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 PVD23178.1 - 1 9.5 33.9 0.89 9.7 1.8 4.6 1 1 4 6 6 6 0 Fibrinogen alpha/beta chain family RPW8 PF05659.11 PVD23178.1 - 1.1 9.0 13.3 0.79 9.4 0.5 4.3 2 2 3 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Seryl_tRNA_N PF02403.22 PVD23178.1 - 1.3 9.3 22.2 5.5 7.3 1.7 4.9 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Bap31_Bap29_C PF18035.1 PVD23178.1 - 1.6 8.8 9.2 1.9 8.6 0.1 3.6 3 1 1 4 4 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain GCN5L1 PF06320.13 PVD23178.1 - 1.6 8.9 15.9 0.085 13.0 2.0 3.9 2 2 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF2730 PF10805.8 PVD23178.1 - 1.7 8.8 16.1 1.6 8.9 0.4 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 PVD23178.1 - 1.8 7.9 15.4 31 3.8 15.4 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 PVD23178.1 - 4.3 7.5 20.2 8.3 6.6 0.1 6.1 6 0 0 6 6 6 0 bZIP transcription factor DASH_Duo1 PF08651.10 PVD23178.1 - 4.6 7.1 19.8 8.4 6.2 0.5 5.0 4 1 0 5 5 5 0 DASH complex subunit Duo1 Golgin_A5 PF09787.9 PVD23178.1 - 5.9 6.3 28.9 5.7 6.3 2.9 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 LMBR1 PF04791.16 PVD23178.1 - 6.5 5.5 14.9 2.1 7.2 9.8 2.4 2 1 0 2 2 2 0 LMBR1-like membrane protein FliJ PF02050.16 PVD23178.1 - 7 6.9 20.3 19 5.5 0.1 4.6 1 1 4 5 5 5 0 Flagellar FliJ protein APG6_N PF17675.1 PVD23178.1 - 7.9 7.0 27.2 0.34 11.4 4.3 4.5 3 1 1 4 4 4 0 Apg6 coiled-coil region Carbpep_Y_N PF05388.11 PVD23178.1 - 9.6 6.8 16.2 2.7 8.6 1.6 4.4 4 2 0 4 4 4 0 Carboxypeptidase Y pro-peptide Galactosyl_T PF01762.21 PVD23179.1 - 1.3e-16 61.0 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 PVD23180.1 - 9e-05 22.4 0.6 0.00013 21.9 0.6 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF2552 PF10827.8 PVD23180.1 - 0.0081 16.3 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2552) Ank_2 PF12796.7 PVD23181.1 - 1.1e-23 83.6 0.1 4.9e-10 39.9 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23181.1 - 1.2e-17 63.8 7.4 5.2e-06 26.6 0.2 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD23181.1 - 1.4e-17 63.8 2.6 2.6e-07 31.0 0.2 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD23181.1 - 1.4e-17 63.3 7.6 0.00035 20.9 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 PVD23181.1 - 8.5e-17 59.5 6.7 0.00015 21.9 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat WCOR413 PF05562.11 PVD23181.1 - 0.0032 17.4 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Cold acclimation protein WCOR413 Ribosomal_S24e PF01282.19 PVD23181.1 - 0.034 14.1 0.1 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S24e DUF243 PF03103.17 PVD23181.1 - 0.18 12.2 1.7 20 5.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Galactosyl_T PF01762.21 PVD23182.1 - 3.5e-37 128.1 0.0 4.3e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD23182.1 - 0.00047 19.7 0.6 0.0011 18.5 0.7 1.6 1 1 0 1 1 1 1 Fringe-like DUF2552 PF10827.8 PVD23182.1 - 0.01 16.0 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) Med23 PF11573.8 PVD23184.1 - 0 1780.4 15.9 0 1780.2 15.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 EF-hand_6 PF13405.6 PVD23185.1 - 1.6e-12 46.3 7.1 7.4e-08 31.7 0.9 3.4 3 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD23185.1 - 2.2e-12 47.2 3.3 6.6e-06 26.5 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD23185.1 - 4.7e-10 38.3 13.5 1.2e-07 30.7 1.6 4.6 5 1 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 PVD23185.1 - 1.2e-05 24.6 6.0 1.7e-05 24.1 1.5 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PVD23185.1 - 8.2e-05 22.4 9.4 0.021 14.7 0.8 3.6 2 1 1 3 3 3 2 EF-hand domain pair UPF0154 PF03672.13 PVD23185.1 - 0.0086 16.1 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) HrpJ PF07201.11 PVD23185.1 - 0.012 16.0 0.1 0.022 15.1 0.0 1.5 2 0 0 2 2 2 0 HrpJ-like domain SPARC_Ca_bdg PF10591.9 PVD23185.1 - 0.053 13.8 0.2 0.097 13.0 0.2 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3741 PF12552.8 PVD23185.1 - 0.096 12.7 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) PDEase_I PF00233.19 PVD23187.1 - 5.3e-40 137.6 2.6 8.6e-40 136.9 2.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mito_fiss_reg PF05308.11 PVD23188.1 - 1.8e-06 28.2 4.0 1.8e-06 28.2 4.0 1.9 2 0 0 2 2 2 1 Mitochondrial fission regulator Mito_fiss_reg PF05308.11 PVD23189.1 - 4e-09 36.9 1.4 2.2e-08 34.5 1.4 2.0 1 1 0 1 1 1 1 Mitochondrial fission regulator T6PP_N PF18572.1 PVD23189.1 - 0.086 12.7 0.2 0.66 9.8 0.0 2.2 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3522 PF12036.8 PVD23190.1 - 1.5e-51 175.3 9.8 2.5e-51 174.6 9.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) EGF_2 PF07974.13 PVD23190.1 - 6.3 7.3 11.8 19 5.7 11.8 1.9 1 0 0 1 1 1 0 EGF-like domain TPMT PF05724.11 PVD23191.1 - 3.6e-47 160.8 0.5 1e-44 152.8 0.0 2.0 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Latarcin PF10279.9 PVD23192.1 - 0.00077 19.8 0.3 8 6.9 1.5 3.7 2 1 0 2 2 2 2 Latarcin precursor Trypan_PARP PF05887.11 PVD23192.1 - 0.0022 17.9 7.1 0.061 13.3 3.0 2.4 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) GRP PF07172.11 PVD23193.1 - 0.011 16.4 0.4 2.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family Conotoxin PF02950.17 PVD23193.1 - 0.02 15.9 4.5 2.6 9.1 0.1 2.6 2 1 1 3 3 3 0 Conotoxin Defensin_propep PF00879.18 PVD23193.1 - 0.026 14.8 1.1 2.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Defensin propeptide Calc_CGRP_IAPP PF00214.19 PVD23193.1 - 0.08 13.3 0.2 2.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Myticin-prepro PF10690.9 PVD23193.1 - 0.43 10.8 3.0 1.3 9.3 0.1 2.7 2 1 0 2 2 2 0 Myticin pre-proprotein from the mussel Calc_CGRP_IAPP PF00214.19 PVD23194.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Conotoxin PF02950.17 PVD23195.1 - 0.011 16.7 0.0 0.014 16.4 0.0 1.2 1 0 0 1 1 1 0 Conotoxin LEAP-2 PF07359.11 PVD23195.1 - 0.12 12.2 0.3 0.24 11.3 0.3 1.5 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Calc_CGRP_IAPP PF00214.19 PVD23195.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.6 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family FAM176 PF14851.6 PVD23196.1 - 0.081 12.6 0.8 0.077 12.7 0.8 1.0 1 0 0 1 1 1 0 FAM176 family p450 PF00067.22 PVD23197.1 - 2.6e-12 46.2 0.0 4.7e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD23198.1 - 2.4e-40 138.7 0.0 3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ArAE_2 PF10334.9 PVD23199.1 - 0.00068 19.5 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF148 PF02520.17 PVD23199.1 - 0.054 13.6 0.5 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 MCPsignal PF00015.21 PVD23199.1 - 0.061 13.1 0.3 0.088 12.6 0.3 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 PVD23199.1 - 0.33 11.0 2.9 1.3 9.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PT PF04886.12 PVD23201.1 - 0.014 14.9 43.9 6.3e+02 0.0 43.9 2.6 1 1 0 1 1 1 0 PT repeat Presenilin PF01080.17 PVD23201.1 - 0.073 11.8 4.7 0.08 11.7 4.7 1.0 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 PVD23201.1 - 0.39 9.4 7.3 0.45 9.2 7.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.7 PVD23201.1 - 0.67 8.0 8.3 0.77 7.8 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 PVD23201.1 - 1.9 8.0 22.2 2.5 7.6 22.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF3408 PF11888.8 PVD23201.1 - 2 8.6 9.4 3 8.0 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.12 PVD23201.1 - 2.4 7.9 7.5 3 7.6 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 PVD23201.1 - 2.4 7.1 4.3 3 6.8 4.3 1.0 1 0 0 1 1 1 0 CLN3 protein RBP_receptor PF14752.6 PVD23201.1 - 2.8 6.4 7.0 3.5 6.1 7.0 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor DUF4820 PF16091.5 PVD23201.1 - 3.9 6.8 8.6 16 4.8 8.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4106 PF13388.6 PVD23201.1 - 5 6.2 24.7 6.4 5.9 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pex14_N PF04695.13 PVD23201.1 - 5.5 7.6 14.8 7.9 7.1 14.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PVD23201.1 - 6.8 6.6 9.9 8.2 6.3 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TIR_2 PF13676.6 PVD23202.1 - 4.7e-10 40.1 0.1 8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD23202.1 - 0.01 15.6 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 TIR domain DUF4481 PF14800.6 PVD23205.1 - 0.019 14.4 0.4 0.023 14.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) SnoaL_4 PF13577.6 PVD23205.1 - 0.05 13.7 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Ion_trans PF00520.31 PVD23206.1 - 3.1e-05 23.3 18.3 0.00014 21.2 18.2 1.9 1 1 0 1 1 1 1 Ion transport protein DUF4293 PF14126.6 PVD23206.1 - 0.0037 17.5 0.2 0.0037 17.5 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4293) K-box PF01486.17 PVD23206.1 - 0.29 11.4 1.2 0.74 10.0 0.1 2.1 2 0 0 2 2 2 0 K-box region PX PF00787.24 PVD23207.1 - 4e-23 81.5 3.1 1e-22 80.2 3.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 PVD23207.1 - 2.6e-05 23.9 6.1 0.00018 21.2 6.1 2.1 1 1 0 1 1 1 1 Vps5 C terminal like GvpK PF05121.12 PVD23207.1 - 0.025 14.6 1.6 0.37 10.9 0.4 2.8 2 0 0 2 2 2 0 Gas vesicle protein K Cep57_MT_bd PF06657.13 PVD23207.1 - 0.26 11.7 6.8 2.2 8.8 0.5 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tctex-1 PF03645.13 PVD23208.1 - 9.6e-17 61.1 0.1 1.4e-16 60.6 0.1 1.3 1 1 0 1 1 1 1 Tctex-1 family RIC1 PF07064.13 PVD23209.1 - 3.7e-88 295.2 0.7 7.7e-88 294.1 0.1 1.9 2 0 0 2 2 2 1 RIC1 APG12 PF04110.13 PVD23209.1 - 0.15 12.5 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Peptidase_M14 PF00246.24 PVD23210.1 - 5.6e-24 85.4 0.0 1.7e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 PVD23210.1 - 2.7e-15 56.7 0.7 4.9e-15 55.8 0.7 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 PVD23210.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family RRM_1 PF00076.22 PVD23211.1 - 7.8e-64 211.4 0.0 1.5e-20 72.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD23211.1 - 1.3e-11 44.1 0.0 9.7e-05 22.0 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD23211.1 - 0.0016 18.2 0.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 PVD23211.1 - 0.0049 16.9 0.0 4.7 7.3 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Cytochrom_B558a PF05038.13 PVD23218.1 - 0.59 9.7 1.9 0.42 10.2 0.2 1.7 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit CAAP1 PF15335.6 PVD23219.1 - 1e-14 54.8 0.1 1.7e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 zf-C2H2_4 PF13894.6 PVD23220.1 - 0.00094 19.8 0.5 0.0016 19.1 0.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD23220.1 - 0.028 14.9 0.6 0.045 14.2 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-CRD PF17979.1 PVD23221.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-C2H2 PF00096.26 PVD23221.1 - 0.014 15.9 4.9 0.03 14.8 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD23221.1 - 0.055 14.3 5.3 0.15 12.9 5.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 PVD23221.1 - 0.16 12.4 5.7 0.37 11.3 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PVD23222.1 - 7.7e-10 38.8 75.6 0.25 12.3 3.3 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD23222.1 - 1.6e-07 31.4 78.5 0.018 15.5 2.0 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-met PF12874.7 PVD23222.1 - 6.9e-05 23.1 51.9 0.014 15.7 0.1 8.7 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-CRD PF17979.1 PVD23222.1 - 0.00032 20.8 21.3 0.086 12.9 0.8 6.1 6 1 0 6 6 6 3 Cysteine rich domain with multizinc binding regions zf-C2H2_2 PF12756.7 PVD23222.1 - 0.01 16.1 2.1 0.01 16.1 2.1 7.4 6 2 1 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 PVD23222.1 - 0.42 10.5 12.5 0.59 10.0 0.1 4.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Apis_Csd PF11671.8 PVD23222.1 - 1.1 9.2 11.4 0.39 10.7 8.1 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein DUF629 PF04780.12 PVD23222.1 - 7.5 5.0 39.2 0.43 9.1 0.5 6.8 7 1 1 8 8 8 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 PVD23222.1 - 9.8 6.6 58.2 0.24 11.8 0.3 8.6 8 2 0 8 8 8 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 PVD23226.1 - 4.1e-68 229.6 0.0 5.5e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23226.1 - 1.1e-38 133.0 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD23226.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD23226.1 - 0.005 16.2 0.1 0.0086 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_5 PF13444.6 PVD23226.1 - 0.065 14.0 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FlgM PF04316.13 PVD23226.1 - 0.078 13.4 0.0 0.41 11.0 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Phage_T7_Capsid PF05396.11 PVD23226.1 - 0.09 13.1 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein DCAF15_WD40 PF14939.6 PVD23227.1 - 2e-57 194.3 0.3 3.7e-57 193.5 0.3 1.4 1 0 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat CAF1 PF04857.20 PVD23228.1 - 7.7e-60 202.7 0.0 5.1e-56 190.2 0.0 2.2 1 1 0 1 1 1 1 CAF1 family ribonuclease zf-CCCH PF00642.24 PVD23228.1 - 0.16 12.0 1.0 0.38 10.7 1.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PVD23228.1 - 0.16 12.6 1.1 0.4 11.4 0.3 1.8 1 1 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 PVD23228.1 - 0.54 10.4 5.2 1.5 9.0 5.2 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 PVD23228.1 - 4.9 7.8 6.5 2.8 8.6 3.6 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_S28e PF01200.18 PVD23229.1 - 3.5e-34 116.6 0.7 3.9e-34 116.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e CrgA PF06781.12 PVD23230.1 - 0.0033 17.4 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Cell division protein CrgA ISK_Channel PF02060.15 PVD23230.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Gln-synt_C PF00120.24 PVD23231.1 - 1.2e-128 428.9 0.2 2.2e-71 240.6 0.0 3.2 2 1 1 3 3 3 3 Glutamine synthetase, catalytic domain TFIIF_beta_N PF17683.1 PVD23231.1 - 0.0095 16.6 0.0 9.4 6.9 0.0 2.7 3 0 0 3 3 3 2 TFIIF, beta subunit N-terminus DiSB-ORF2_chro PF16506.5 PVD23231.1 - 0.055 13.5 0.0 23 5.1 0.0 2.8 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses Gln-synt_N PF03951.19 PVD23231.1 - 0.084 12.6 0.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain ROQ_II PF18386.1 PVD23231.1 - 0.14 12.0 0.6 24 4.9 0.1 2.5 2 0 0 2 2 2 0 Roquin II domain Gln-synt_C PF00120.24 PVD23232.1 - 1.8e-71 241.0 0.0 2.7e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain TMEM154 PF15102.6 PVD23233.1 - 2.2e-06 27.6 0.3 3.1e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PVD23233.1 - 0.00054 20.8 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Pilin_N PF07790.11 PVD23233.1 - 0.0057 17.6 0.5 5.1 8.1 0.0 2.9 2 1 1 3 3 3 1 Archaeal Type IV pilin, N-terminal DAG1 PF05454.11 PVD23233.1 - 0.007 15.8 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5305 PF17231.2 PVD23233.1 - 0.007 15.8 0.2 0.0093 15.4 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) MAM PF00629.23 PVD23233.1 - 0.0092 15.9 1.9 0.01 15.8 0.1 1.8 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu DUF4064 PF13273.6 PVD23233.1 - 0.01 16.1 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF5383 PF17355.2 PVD23233.1 - 0.026 14.9 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF3377 PF11857.8 PVD23233.1 - 0.091 12.7 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CcmH PF03918.14 PVD23233.1 - 0.11 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TMPIT PF07851.13 PVD23234.1 - 0.84 8.8 8.9 1.4 8.1 8.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.19 PVD23234.1 - 1.8 8.4 37.2 0.021 14.6 29.2 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Ax_dynein_light PF10211.9 PVD23234.1 - 3.3 7.6 20.1 0.31 11.0 12.9 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4482 PF14818.6 PVD23234.1 - 5.7 7.8 23.6 0.46 11.4 18.6 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) CAF-1_p150 PF11600.8 PVD23234.1 - 6.1 6.5 39.1 0.073 12.8 29.0 2.3 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hid1 PF12722.7 PVD23234.1 - 8.6 4.3 8.5 10 4.1 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 7tm_1 PF00001.21 PVD23235.1 - 3.8e-57 193.6 0.1 4.7e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD23235.1 - 4.4e-09 36.5 4.4 7.8e-09 35.7 4.4 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD23235.1 - 3.2e-06 27.0 14.6 5.1e-06 26.3 14.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD23235.1 - 7.3e-05 22.3 6.4 7.3e-05 22.3 6.4 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD23235.1 - 0.0026 17.1 8.9 0.16 11.2 6.2 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 PVD23235.1 - 0.0027 17.1 12.0 0.051 12.9 8.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv DUF3708 PF12501.8 PVD23235.1 - 0.083 12.7 0.4 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter fn3 PF00041.21 PVD23236.1 - 5e-80 263.9 9.4 7.3e-14 51.9 2.7 9.7 10 0 0 10 10 9 9 Fibronectin type III domain Ig_3 PF13927.6 PVD23236.1 - 4.5e-29 100.9 2.8 1.4e-08 35.2 0.0 5.4 5 0 0 5 5 4 3 Immunoglobulin domain I-set PF07679.16 PVD23236.1 - 2.5e-27 94.8 0.0 1.8e-11 44.0 0.0 4.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD23236.1 - 1.7e-21 76.3 0.2 5.5e-08 33.0 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD23236.1 - 6e-21 74.4 0.1 1.1e-06 28.7 0.1 4.4 3 1 0 3 3 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD23236.1 - 8.3e-21 74.4 9.5 0.00013 22.4 1.4 8.9 9 0 0 9 9 9 4 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 PVD23236.1 - 8.5e-19 67.7 2.0 5.2e-09 36.3 0.1 4.1 4 0 0 4 4 4 2 Immunoglobulin V-set domain DUF2369 PF10179.9 PVD23236.1 - 1.7e-06 28.3 0.4 19 5.7 0.0 7.3 9 0 0 9 9 8 0 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 PVD23236.1 - 0.00013 22.4 1.7 5.5 7.6 0.0 5.7 6 0 0 6 6 5 1 PhoD-like phosphatase, N-terminal domain fn3_4 PF16794.5 PVD23236.1 - 0.00059 19.7 0.0 2 8.4 0.0 5.1 4 1 0 4 4 4 1 Fibronectin-III type domain Ig_6 PF18452.1 PVD23236.1 - 0.0018 17.8 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD23236.1 - 0.0036 17.3 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 PVD23236.1 - 0.0059 16.8 0.2 6.5 7.0 0.1 3.4 2 1 1 3 3 3 1 Natural killer cell receptor 2B4 Glyco_hydro_36C PF16874.5 PVD23236.1 - 0.012 16.0 0.5 40 4.8 0.0 5.1 6 0 0 6 6 5 0 Glycosyl hydrolase family 36 C-terminal domain Izumo-Ig PF16706.5 PVD23236.1 - 0.03 14.4 0.0 3.3 7.8 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain PKD PF00801.20 PVD23236.1 - 0.031 14.1 1.3 3.1 7.7 0.1 3.9 3 0 0 3 3 3 0 PKD domain DUF4912 PF16258.5 PVD23236.1 - 0.04 14.1 0.0 6.6 7.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4912) C1-set PF07654.15 PVD23236.1 - 0.056 13.8 0.2 7 7.1 0.0 4.3 5 0 0 5 5 5 0 Immunoglobulin C1-set domain Arylsulfotran_N PF17425.2 PVD23236.1 - 0.07 13.2 0.5 1.8 8.6 0.2 3.3 3 0 0 3 3 3 0 Arylsulfotransferase Ig-like domain HLH PF00010.26 PVD23239.1 - 7e-14 51.5 1.7 9.5e-14 51.1 0.8 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PPV_E1_N PF00524.18 PVD23239.1 - 0.039 14.4 1.8 0.059 13.8 0.7 1.8 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.32 PVD23240.1 - 4.3e-11 43.2 4.1 0.046 14.6 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat LRR_4 PF12799.7 PVD23241.1 - 3e-10 40.2 5.2 0.00013 22.3 3.0 3.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD23241.1 - 3.8e-06 26.5 0.4 3.4e-05 23.4 0.4 2.2 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD23241.1 - 3.2e-05 23.6 7.6 0.0054 16.5 1.1 3.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 PVD23241.1 - 0.061 13.9 4.4 7.1 7.6 0.4 4.6 5 1 0 5 5 5 0 Leucine Rich Repeat HtrL_YibB PF09612.10 PVD23242.1 - 2.5e-17 63.3 4.6 5.2e-17 62.2 4.6 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Autophagy_act_C PF03987.15 PVD23243.1 - 3.3e-20 72.4 2.9 7.2e-20 71.3 2.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ydhR PF08803.11 PVD23243.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR MBT PF02820.18 PVD23244.1 - 5.6e-84 276.5 3.0 1.6e-29 102.0 0.3 3.5 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 PVD23244.1 - 4.9e-24 84.2 25.9 2.2e-14 53.3 8.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.30 PVD23244.1 - 1.6e-07 31.6 0.0 3.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GST_C PF00043.25 PVD23244.1 - 0.00012 22.2 0.1 0.0005 20.2 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD23244.1 - 0.0075 16.5 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD23244.1 - 0.0093 16.0 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-FCS PF06467.14 PVD23244.1 - 1.2 9.2 7.8 11 6.1 7.8 2.4 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PCMT PF01135.19 PVD23245.1 - 1.4e-21 77.2 0.0 2.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 PVD23245.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 PVD23245.1 - 0.0021 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SOCS_box PF07525.16 PVD23245.1 - 0.0032 17.8 10.1 0.13 12.6 0.6 3.4 3 0 0 3 3 3 2 SOCS box GCD14 PF08704.10 PVD23245.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.1 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Importin_rep_4 PF18808.1 PVD23245.1 - 0.017 15.4 0.3 0.037 14.3 0.3 1.6 1 0 0 1 1 1 0 Importin repeat Methyltransf_25 PF13649.6 PVD23245.1 - 0.039 14.7 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 PVD23245.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-C2HC PF01530.18 PVD23246.1 - 7e-62 205.2 50.0 4.1e-16 58.8 7.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2HC type CENP-F_leu_zip PF10473.9 PVD23246.1 - 0.00029 20.9 4.8 0.00059 19.9 4.8 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MYT1 PF08474.11 PVD23246.1 - 0.00072 19.6 0.7 0.0015 18.5 0.7 1.7 1 1 0 1 1 1 1 Myelin transcription factor 1 GIT_CC PF16559.5 PVD23246.1 - 0.0024 17.7 0.6 0.23 11.3 0.0 2.8 1 1 1 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 PVD23246.1 - 0.012 15.6 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cast PF10174.9 PVD23246.1 - 0.014 13.7 1.9 0.018 13.3 1.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF5082 PF16888.5 PVD23246.1 - 0.015 15.6 0.2 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 PVD23246.1 - 0.024 14.7 1.9 0.065 13.2 1.9 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 PVD23246.1 - 0.029 14.5 0.2 0.06 13.4 0.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 PVD23246.1 - 0.06 13.8 1.1 1.3 9.5 1.1 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APC_N_CC PF16689.5 PVD23246.1 - 0.067 13.3 0.8 0.19 11.8 0.8 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain IBR PF01485.21 PVD23246.1 - 0.081 13.2 9.9 4.7 7.5 0.1 4.5 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain Spc7 PF08317.11 PVD23246.1 - 0.09 11.6 3.4 0.13 11.1 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Rootletin PF15035.6 PVD23246.1 - 0.12 12.4 1.2 0.19 11.7 1.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Gp58 PF07902.11 PVD23246.1 - 0.14 10.4 0.4 0.24 9.6 0.4 1.3 1 0 0 1 1 1 0 gp58-like protein FlaC_arch PF05377.11 PVD23246.1 - 0.16 12.4 2.0 5.6 7.4 0.3 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 PVD23246.1 - 0.16 12.2 3.3 0.27 11.4 3.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 PVD23246.1 - 0.16 11.3 1.5 0.34 10.2 1.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 PVD23246.1 - 0.19 12.2 3.1 2.5 8.6 3.1 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 PVD23246.1 - 0.54 10.4 4.7 0.74 10.0 2.6 1.8 1 1 1 2 2 2 0 Tropomyosin like APG6_N PF17675.1 PVD23246.1 - 0.77 10.3 5.6 0.63 10.6 4.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-RAG1 PF10426.9 PVD23246.1 - 3.7 7.8 8.0 57 4.0 0.0 4.7 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain UPF0257 PF06788.13 PVD23247.1 - 0.044 13.6 2.4 0.075 12.8 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) WD40 PF00400.32 PVD23248.1 - 2.6e-12 47.0 19.9 5.4e-05 23.9 0.0 6.6 5 2 0 5 5 5 3 WD domain, G-beta repeat TPR_19 PF14559.6 PVD23249.1 - 1.2e-12 48.2 0.0 1.8e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD23249.1 - 8.5e-11 41.1 0.1 0.0012 18.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23249.1 - 8.4e-09 34.9 0.5 0.0018 18.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD23249.1 - 2.3e-07 31.0 0.8 0.00085 19.6 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD23249.1 - 1.8e-05 24.8 0.4 0.0045 17.2 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PVD23249.1 - 6.3e-05 22.9 3.0 0.87 10.0 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD23249.1 - 6.8e-05 23.4 0.0 0.022 15.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD23249.1 - 0.00074 19.0 0.6 0.15 11.5 0.1 2.9 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_7 PF13176.6 PVD23249.1 - 0.00088 19.1 0.0 4 7.7 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 PVD23249.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 PVD23249.1 - 0.0027 18.2 0.1 1.2 9.9 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD23249.1 - 0.0092 16.7 0.9 9 7.4 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD23249.1 - 0.016 15.3 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD23249.1 - 0.12 12.8 1.3 1.2 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD23249.1 - 0.26 11.4 1.9 5.5 7.2 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF5588 PF17826.1 PVD23250.1 - 3e-21 75.7 6.8 6.5e-19 68.0 1.3 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5588) TPR_2 PF07719.17 PVD23250.1 - 8.5e-05 22.4 3.4 0.34 11.1 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23250.1 - 0.00013 22.4 0.5 0.36 11.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Muted PF14942.6 PVD23250.1 - 0.014 15.7 6.4 0.087 13.2 4.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein TPR_12 PF13424.6 PVD23250.1 - 0.017 15.4 1.6 0.7 10.2 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2299 PF10061.9 PVD23250.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) TPR_16 PF13432.6 PVD23250.1 - 0.068 13.8 0.1 16 6.3 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Pox_H7 PF04787.12 PVD23250.1 - 0.1 13.1 1.5 0.15 12.6 0.1 1.9 2 1 1 3 3 3 0 Late protein H7 TPR_8 PF13181.6 PVD23250.1 - 0.14 12.4 2.7 0.74 10.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23250.1 - 4.4 7.3 6.1 36 4.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tctex-1 PF03645.13 PVD23251.1 - 6.8e-21 74.4 1.2 9.7e-21 73.9 1.2 1.2 1 0 0 1 1 1 1 Tctex-1 family UBA PF00627.31 PVD23252.1 - 2.5e-24 84.8 5.9 4.5e-13 48.8 0.7 2.6 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 PVD23252.1 - 2.1e-23 81.8 10.4 3.4e-23 81.1 10.4 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 PVD23252.1 - 9e-21 73.4 2.0 1.5e-20 72.7 2.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD23252.1 - 1.3e-06 28.1 3.5 2.2e-06 27.4 3.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 PVD23252.1 - 0.00045 20.0 0.0 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 PVD23252.1 - 0.0013 18.8 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 PVD23252.1 - 0.028 14.1 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 CUE domain DUF2407 PF10302.9 PVD23252.1 - 0.04 14.5 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 PVD23252.1 - 0.04 13.9 2.8 1.3 9.2 2.7 2.3 1 1 0 1 1 1 0 Ubiquitin-like domain SP_C-Propep PF08999.10 PVD23252.1 - 0.058 13.2 1.9 0.13 12.1 1.7 1.7 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Ubiquitin_5 PF18037.1 PVD23252.1 - 0.08 13.3 1.2 0.14 12.5 1.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4566 PF15130.6 PVD23253.1 - 4.8e-120 399.0 0.7 5.5e-120 398.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) Reeler PF02014.16 PVD23254.1 - 1.4e-22 80.8 0.0 3.4e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 PVD23254.1 - 8.8e-17 61.5 0.2 1.8e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 DOMON domain HPS6 PF15702.5 PVD23254.1 - 2.7e-11 42.3 4.0 5e-06 24.8 0.9 2.2 2 0 0 2 2 2 2 Hermansky-Pudlak syndrome 6 protein Cytochrom_B561 PF03188.16 PVD23254.1 - 1.1e-06 28.8 3.7 1.1e-06 28.8 3.7 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 PVD23254.1 - 0.088 13.0 2.3 0.16 12.2 1.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF433 PF04255.14 PVD23254.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Reeler PF02014.16 PVD23255.1 - 8.4e-12 46.0 0.0 2.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Reeler domain Suf PF05843.14 PVD23255.1 - 0.64 9.9 3.7 0.85 9.5 3.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 PVD23255.1 - 1.3 9.0 7.1 1.4 8.8 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Reeler PF02014.16 PVD23256.1 - 2.6e-52 177.0 1.0 5.3e-25 88.6 0.1 3.1 3 0 0 3 3 3 2 Reeler domain DOMON PF03351.17 PVD23256.1 - 1.6e-29 102.6 3.0 6.7e-15 55.4 0.3 2.5 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 PVD23256.1 - 1.1e-19 70.9 19.7 4.3e-11 43.1 5.1 2.7 2 1 0 2 2 2 2 Eukaryotic cytochrome b561 fn3 PF00041.21 PVD23256.1 - 0.0099 16.2 1.6 32 5.0 0.0 4.9 6 0 0 6 6 6 0 Fibronectin type III domain DUF4079 PF13301.6 PVD23256.1 - 0.43 10.7 21.7 2.1 8.5 6.8 4.3 3 2 0 3 3 3 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 PVD23256.1 - 0.52 9.9 24.6 0.47 10.0 3.2 4.1 2 2 2 4 4 4 0 Prokaryotic cytochrome b561 Ank_2 PF12796.7 PVD23257.1 - 3.3e-87 287.2 28.0 8.2e-17 61.6 0.0 15.2 6 3 10 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD23257.1 - 1.3e-76 252.1 35.9 1.3e-09 38.4 0.1 20.7 14 6 7 21 21 21 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD23257.1 - 2.5e-67 222.0 31.2 1.6e-07 31.5 0.1 19.1 15 4 4 19 19 19 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23257.1 - 3.7e-54 174.3 34.1 1.1e-05 25.4 0.0 25.2 27 0 0 27 27 27 13 Ankyrin repeat Ank PF00023.30 PVD23257.1 - 3.5e-53 175.8 36.2 2.4e-06 27.7 0.0 22.9 24 0 0 24 24 24 8 Ankyrin repeat PARP PF00644.20 PVD23257.1 - 3.2e-28 98.7 0.1 3.2e-28 98.7 0.1 2.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 PVD23257.1 - 1.3e-21 76.4 0.7 3.1e-21 75.2 0.7 1.7 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 PVD23257.1 - 6.3e-19 68.4 1.0 2e-18 66.8 1.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Semialdhyde_dh PF01118.24 PVD23257.1 - 0.13 12.7 0.1 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Eapp_C PF10238.9 PVD23257.1 - 3.6 7.6 7.4 28 4.7 0.3 3.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein RCC1 PF00415.18 PVD23258.1 - 1.4e-70 233.7 17.1 5.4e-14 52.5 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat TBP PF00352.21 PVD23258.1 - 1.4e-41 140.3 0.1 4.9e-22 77.7 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) RCC1_2 PF13540.6 PVD23258.1 - 3.2e-32 109.6 32.9 8.7e-10 38.1 0.2 9.5 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat DUF2786 PF10979.8 PVD23258.1 - 0.019 14.8 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) F5_F8_type_C PF00754.25 PVD23260.1 - 8.5e-05 22.7 0.0 0.001 19.2 0.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain Laminin_EGF PF00053.24 PVD23260.1 - 0.0047 17.0 144.5 13 6.0 6.6 10.0 2 2 7 9 9 9 4 Laminin EGF domain Ank_2 PF12796.7 PVD23261.1 - 6.4e-21 74.7 1.5 1.8e-08 34.9 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD23261.1 - 7.1e-19 67.9 0.2 1.7e-10 41.2 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD23261.1 - 3.1e-15 56.0 3.7 4.8e-09 36.3 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23261.1 - 4.2e-12 45.1 0.2 0.0016 18.8 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PVD23261.1 - 9.6e-11 41.6 4.8 2.6e-05 24.5 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat UBX PF00789.20 PVD23262.1 - 2e-15 56.7 0.0 7.7e-15 54.9 0.0 2.1 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PVD23262.1 - 1.8e-08 34.0 0.1 4.3e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.23 PVD23262.1 - 6.6e-07 29.0 0.0 0.0051 16.5 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family DUF1682 PF07946.14 PVD23262.1 - 0.015 14.5 10.4 0.026 13.8 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ubiquitin_2 PF14560.6 PVD23262.1 - 0.026 15.0 0.0 7.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Ubiquitin-like domain DUF572 PF04502.13 PVD23262.1 - 0.082 12.5 6.9 0.17 11.5 6.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Caldesmon PF02029.15 PVD23262.1 - 8.3 5.0 22.4 16 4.1 22.4 1.4 1 0 0 1 1 1 0 Caldesmon DUF4614 PF15391.6 PVD23263.1 - 2.1e-12 47.4 1.3 2.1e-12 47.4 1.3 6.0 2 2 4 6 6 6 1 Domain of unknown function (DUF4614) DUF2785 PF10978.8 PVD23263.1 - 0.13 12.1 0.3 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) PID PF00640.23 PVD23264.1 - 4.5e-07 30.0 0.0 7.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Tektin PF03148.14 PVD23265.1 - 1.9e-138 461.4 37.0 2.1e-138 461.2 37.0 1.0 1 0 0 1 1 1 1 Tektin family DUF1043 PF06295.12 PVD23265.1 - 0.0038 17.2 0.9 0.0038 17.2 0.9 4.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1043) DUF1664 PF07889.12 PVD23265.1 - 0.004 17.2 19.0 0.3 11.1 1.1 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF1664) betaPIX_CC PF16523.5 PVD23265.1 - 0.027 14.3 0.3 0.027 14.3 0.3 2.7 2 1 1 3 3 3 0 betaPIX coiled coil LIF_OSM PF01291.17 PVD23265.1 - 0.039 14.1 4.4 0.053 13.7 0.5 2.8 2 2 1 3 3 3 0 LIF / OSM family Endotoxin_C2 PF18449.1 PVD23265.1 - 0.084 13.2 2.9 3.1 8.2 0.9 2.9 2 0 0 2 2 2 0 Delta endotoxin DUF4795 PF16043.5 PVD23265.1 - 0.46 10.1 24.2 0.069 12.8 8.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Nas2_N PF18265.1 PVD23265.1 - 2.1 8.3 15.4 0.32 10.9 0.9 4.4 3 2 0 3 3 3 0 Nas2 N_terminal domain LPP PF04728.13 PVD23265.1 - 5.8 7.4 12.3 2.5 8.6 0.4 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF4600 PF15372.6 PVD23265.1 - 7.4 7.0 21.5 0.054 13.9 6.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4600) Lipase PF00151.19 PVD23267.1 - 4.2e-71 240.0 0.0 6.2e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Lipase DUF3472 PF11958.8 PVD23267.1 - 8.3e-24 85.0 0.5 1.4e-23 84.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 PVD23267.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) Metallothio_Euk PF12749.7 PVD23268.1 - 0.012 15.8 18.6 0.019 15.1 18.6 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein Fe_dep_repress PF01325.19 PVD23268.1 - 0.4 10.9 1.0 15 5.8 0.2 2.3 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain LacI PF00356.21 PVD23268.1 - 0.41 10.5 4.8 1.3 8.8 1.7 2.4 1 1 1 2 2 2 0 Bacterial regulatory proteins, lacI family IL23 PF16649.5 PVD23270.1 - 0.18 11.9 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Interleukin 23 subunit alpha DAGK_cat PF00781.24 PVD23271.1 - 2.1e-25 88.8 0.0 3.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1533 PF07550.11 PVD23271.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) Mito_carr PF00153.27 PVD23272.1 - 3.3e-50 168.0 0.3 1.2e-18 66.8 0.0 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 PVD23272.1 - 0.00099 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Fuseless Mito_carr PF00153.27 PVD23273.1 - 1.3e-61 204.5 4.1 5.2e-23 80.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 PVD23273.1 - 0.0091 15.2 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 Fuseless DUF572 PF04502.13 PVD23274.1 - 1.7e-70 238.3 3.8 2e-70 238.0 3.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ZZ PF00569.17 PVD23274.1 - 0.11 12.3 3.9 6.2 6.7 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Zn-ribbon_8 PF09723.10 PVD23274.1 - 0.37 10.9 2.1 0.38 10.9 0.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain hDGE_amylase PF14701.6 PVD23275.1 - 1.6e-144 482.3 0.1 2.3e-144 481.7 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 PVD23275.1 - 8.6e-75 251.7 0.0 1.5e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 PVD23275.1 - 1.3e-19 70.1 0.0 2.4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 PVD23275.1 - 1.7e-05 24.6 0.0 5.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Abhydrolase_2 PF02230.16 PVD23276.1 - 1.2e-70 237.7 0.0 1.9e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase KH_6 PF15985.5 PVD23276.1 - 9.8e-14 51.4 0.0 2.4e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 PVD23276.1 - 3.7e-12 45.8 0.1 8.3e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Abhydrolase_6 PF12697.7 PVD23276.1 - 5.8e-07 30.3 0.0 1e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD23276.1 - 0.00028 20.2 0.1 0.53 9.5 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 PVD23276.1 - 0.00056 19.8 0.0 0.0018 18.2 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 PVD23276.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 PVD23276.1 - 0.0044 16.7 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 PVD23276.1 - 0.065 11.9 0.0 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 PVD23276.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Mg_trans_NIPA PF05653.14 PVD23277.1 - 1.3e-68 231.3 20.1 1.5e-68 231.1 20.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 PVD23277.1 - 2.9e-08 34.0 0.7 2.9e-08 34.0 0.7 3.5 2 1 0 3 3 3 1 EamA-like transporter family TMEM132D_C PF15706.5 PVD23277.1 - 0.41 10.5 0.0 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term JAMP PF05571.12 PVD23277.1 - 0.42 10.2 10.5 0.63 9.6 10.5 1.3 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Dr_adhesin PF12393.8 PVD23277.1 - 4.2 7.8 5.7 9.1 6.8 0.2 3.4 2 0 0 2 2 2 0 Dr family adhesin Rtf2 PF04641.12 PVD23278.1 - 3.5e-85 285.5 13.5 4.9e-85 285.0 13.5 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Nefa_Nip30_N PF10187.9 PVD23278.1 - 0.13 12.6 0.5 0.13 12.6 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF5434 PF17502.2 PVD23278.1 - 0.44 10.5 7.0 0.52 10.3 1.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5434) GDP_Man_Dehyd PF16363.5 PVD23279.1 - 2.2e-55 188.4 0.0 3.2e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD23279.1 - 4.4e-50 170.4 0.0 6e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD23279.1 - 2.3e-16 59.6 0.0 3.4e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PVD23279.1 - 2.6e-15 56.3 0.1 4.9e-14 52.2 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PVD23279.1 - 2.3e-10 40.0 0.0 3.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PVD23279.1 - 1.2e-07 31.1 0.0 1e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein KR PF08659.10 PVD23279.1 - 3.8e-06 26.9 0.0 8.8e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PVD23279.1 - 1.5e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 PVD23279.1 - 0.00031 20.2 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 PVD23279.1 - 0.0044 16.6 0.2 0.89 9.1 0.1 2.3 2 0 0 2 2 2 2 NmrA-like family UDPG_MGDP_dh_N PF03721.14 PVD23279.1 - 0.17 11.5 0.1 0.6 9.7 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.21 PVD23280.1 - 1.2e-21 77.3 0.0 1.4e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD23280.1 - 7.2e-12 45.4 0.0 8.3e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MMACHC PF16690.5 PVD23281.1 - 2.2e-97 325.0 0.1 2.5e-97 324.8 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Claudin_3 PF06653.11 PVD23282.1 - 0.00036 20.5 6.9 0.00064 19.7 6.9 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 PVD23282.1 - 0.078 12.7 19.4 11 5.6 19.4 2.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.23 PVD23282.1 - 7.3 6.6 24.0 5.4e+02 0.6 0.9 2.9 1 1 1 2 2 2 0 Membrane-associating domain Zip PF02535.22 PVD23282.1 - 8.1 5.6 7.6 12 5.0 6.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_C54 PF03416.19 PVD23283.1 - 5.9e-107 357.2 0.2 8.9e-107 356.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family C54 7tm_1 PF00001.21 PVD23286.1 - 9.6e-16 57.9 4.2 1.9e-15 56.9 4.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23286.1 - 0.00043 19.8 3.0 0.00073 19.0 3.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx BenE PF03594.13 PVD23286.1 - 0.0055 15.5 0.2 0.0079 15.0 0.2 1.2 1 0 0 1 1 1 1 Benzoate membrane transport protein YbhQ PF11076.8 PVD23286.1 - 0.012 15.7 3.1 0.018 15.0 3.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF2109 PF09882.9 PVD23286.1 - 0.12 12.4 4.5 0.21 11.6 4.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) 7tm_1 PF00001.21 PVD23288.1 - 7.7e-19 68.0 9.0 9.1e-19 67.8 9.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF973 PF06157.11 PVD23288.1 - 0.05 12.7 2.3 0.062 12.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) COPI_C PF06957.11 PVD23288.1 - 0.18 10.6 0.5 0.49 9.1 0.1 1.7 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus 7tm_1 PF00001.21 PVD23289.1 - 0.0011 18.3 0.2 0.0012 18.2 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Replic_Relax PF13814.6 PVD23290.1 - 0.016 15.3 0.1 0.032 14.3 0.0 1.5 2 0 0 2 2 2 0 Replication-relaxation 7tm_1 PF00001.21 PVD23291.1 - 0.013 14.8 1.2 0.014 14.8 1.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD23292.1 - 1.6e-31 109.6 7.4 2.3e-31 109.1 7.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23292.1 - 0.0002 20.8 2.5 0.00026 20.4 2.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD23292.1 - 0.00024 20.8 7.8 0.0003 20.5 7.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23292.1 - 0.00075 19.3 2.3 0.00099 18.9 2.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 PVD23292.1 - 0.042 13.4 7.0 0.061 12.8 7.0 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc Mito_fiss_reg PF05308.11 PVD23293.1 - 0.33 11.0 3.5 0.31 11.1 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD23293.1 - 2.4 7.5 7.7 3.6 7.0 7.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_L27A PF00828.19 PVD23294.1 - 1.6e-23 83.8 0.0 3.6e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glycos_transf_1 PF00534.20 PVD23295.1 - 1.5e-40 138.5 0.0 1.9e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD23295.1 - 4.5e-19 69.2 0.0 7.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PVD23295.1 - 3.5e-06 27.3 0.0 7.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PVD23295.1 - 0.00029 20.9 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_5 PF16994.5 PVD23295.1 - 0.0067 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl-transferase family 4 Furin-like_2 PF15913.5 PVD23296.1 - 3.5e-34 117.2 24.9 3.5e-34 117.2 24.9 2.0 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich eIF3_N PF09440.10 PVD23297.1 - 6.3e-32 110.8 5.1 1.6e-31 109.5 5.1 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 PVD23297.1 - 4.1e-20 72.2 0.2 1.3e-19 70.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 PVD23297.1 - 0.076 13.0 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family WWE PF02825.20 PVD23298.1 - 5.8e-16 58.8 0.4 1.2e-15 57.8 0.4 1.6 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.6 PVD23298.1 - 3.2e-08 33.3 8.3 5e-08 32.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD23298.1 - 7e-06 26.3 9.7 1.1e-05 25.6 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD23298.1 - 1.3e-05 25.0 7.8 2.1e-05 24.3 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD23298.1 - 0.00017 21.5 6.7 0.00037 20.5 6.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD23298.1 - 0.00092 19.0 9.0 0.0015 18.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD23298.1 - 0.00092 19.1 8.3 0.0015 18.4 8.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD23298.1 - 0.0019 18.0 8.9 0.0035 17.1 8.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD23298.1 - 0.0035 17.5 7.7 0.0069 16.5 7.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PVD23298.1 - 0.44 10.7 7.1 0.89 9.7 7.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 PVD23298.1 - 0.49 10.7 7.5 1 9.7 7.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Acyltransf_C PF16076.5 PVD23299.1 - 8.5e-16 57.8 0.2 2.4e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 PVD23299.1 - 1.3e-08 34.5 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF547 PF04784.14 PVD23300.1 - 5.4e-39 133.0 0.0 9.8e-39 132.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.24 PVD23300.1 - 8.9e-16 57.9 0.0 2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 PVD23300.1 - 2.2e-15 56.5 0.3 4.4e-15 55.5 0.3 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GST_N_3 PF13417.6 PVD23300.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 PVD23300.1 - 0.024 15.0 0.1 0.074 13.5 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Apt1 PF10351.9 PVD23301.1 - 0.069 12.0 4.5 0.077 11.8 4.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF809 PF05663.11 PVD23301.1 - 7 6.8 9.0 1.5 9.0 5.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF809) Cadherin_3 PF16184.5 PVD23302.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Cadherin-like zf-C2H2 PF00096.26 PVD23302.1 - 0.07 13.6 0.4 0.19 12.3 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type ISG65-75 PF11727.8 PVD23302.1 - 0.27 10.4 0.3 0.47 9.6 0.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DMAP1 PF05499.12 PVD23303.1 - 2.4e-72 242.2 2.8 2.4e-72 242.2 2.8 1.8 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 PVD23303.1 - 1.1e-33 115.2 2.2 2.4e-33 114.2 2.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Carboxyl_trans PF01039.22 PVD23304.1 - 2.2e-103 346.6 0.0 2.4e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ERCC4 PF02732.15 PVD23305.1 - 3.5e-22 79.3 0.0 8.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.7 PVD23305.1 - 0.03 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ank_4 PF13637.6 PVD23306.1 - 8.1e-23 80.5 3.9 5.8e-12 45.9 0.3 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD23306.1 - 1.2e-18 67.4 0.0 2.9e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23306.1 - 1.4e-13 50.8 2.0 7.3e-06 26.2 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD23306.1 - 1.7e-11 44.0 0.2 0.00095 19.5 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD23306.1 - 8.7e-11 41.1 1.5 0.0045 17.4 0.1 5.6 6 0 0 6 6 6 2 Ankyrin repeat DUF4106 PF13388.6 PVD23308.1 - 5.1 6.2 6.6 5.3 6.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF2371 PF10177.9 PVD23309.1 - 2.3e-05 24.6 0.1 2.3e-05 24.6 0.1 3.5 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2371) SID-1_RNA_chan PF13965.6 PVD23309.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 PVD23309.1 - 0.23 9.7 11.4 0.37 9.0 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 PVD23309.1 - 0.32 9.9 1.6 0.52 9.2 1.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 PVD23309.1 - 0.73 9.1 11.0 1.9 7.8 11.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlgT_M PF16539.5 PVD23310.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain fn3 PF00041.21 PVD23311.1 - 1.2e-10 41.6 2.6 0.00013 22.2 0.0 4.7 4 0 0 4 4 4 3 Fibronectin type III domain fn3_2 PF16893.5 PVD23311.1 - 0.021 15.0 0.0 2.2 8.5 0.0 2.9 3 0 0 3 3 3 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD23311.1 - 0.045 14.3 6.8 0.19 12.3 0.3 3.9 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 PVD23311.1 - 0.36 11.6 4.7 2.2 9.1 0.0 3.4 4 0 0 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArsA_ATPase PF02374.15 PVD23312.1 - 6.9e-56 189.7 3.7 1.8e-49 168.6 1.9 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase LXG PF04740.12 PVD23312.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily EntA_Immun PF08951.10 PVD23312.1 - 0.18 12.2 1.3 17 5.8 0.1 3.5 3 1 0 3 3 3 0 Enterocin A Immunity RPE65 PF03055.15 PVD23313.1 - 2.7e-86 290.6 0.0 3.5e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PGM_PMM_I PF02878.16 PVD23314.1 - 5.1e-33 113.7 0.1 7.5e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PVD23314.1 - 3.3e-27 94.9 0.0 5.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PVD23314.1 - 1.4e-15 57.8 0.0 3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PVD23314.1 - 3e-05 24.1 0.0 0.00013 22.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Aa_trans PF01490.18 PVD23315.1 - 1.2e-19 70.3 10.7 3.5e-19 68.8 8.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein SARAF PF06682.12 PVD23316.1 - 7.2e-91 305.3 5.6 8.7e-91 305.0 5.6 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RIC3 PF15361.6 PVD23316.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2615 PF11027.8 PVD23316.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) SARAF PF06682.12 PVD23317.1 - 6e-75 252.9 0.3 9e-75 252.4 0.3 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RIC3 PF15361.6 PVD23317.1 - 0.19 12.1 0.0 0.43 11.0 0.0 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 VWA_N PF08399.11 PVD23318.1 - 1.5e-20 73.9 0.1 2.4e-16 60.3 0.0 2.7 2 0 0 2 2 2 2 VWA N-terminal dCache_1 PF02743.18 PVD23318.1 - 2.3e-13 50.5 3.4 0.0011 18.8 0.0 3.9 3 1 0 3 3 3 3 Cache domain VWA PF00092.28 PVD23318.1 - 2.3e-09 37.8 0.0 5.9e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD23318.1 - 6e-08 33.3 0.1 4e-07 30.6 0.1 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD23318.1 - 2.5e-07 30.8 0.2 1.5e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VGCC_alpha2 PF08473.11 PVD23318.1 - 4.7e-05 22.4 1.6 0.0043 15.9 0.1 3.5 4 0 0 4 4 4 1 Neuronal voltage-dependent calcium channel alpha 2acd CobT_C PF11775.8 PVD23318.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain DUF1043 PF06295.12 PVD23318.1 - 0.16 12.0 0.2 0.37 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RIO1 PF01163.22 PVD23319.1 - 2.6e-69 232.6 0.9 5e-69 231.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Peroxin-3 PF04882.12 PVD23319.1 - 9.7e-42 143.5 1.0 6.1e-35 121.1 0.0 3.8 2 1 2 4 4 4 2 Peroxin-3 CDC45 PF02724.14 PVD23319.1 - 1.6 6.9 16.6 0.12 10.7 0.7 2.1 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 PVD23319.1 - 4.2 7.8 16.0 0.82 10.1 5.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase_fungal PF17667.1 PVD23319.1 - 4.2 6.0 11.9 0.94 8.2 3.3 2.6 2 1 0 2 2 2 0 Fungal protein kinase Tetraspanin PF00335.20 PVD23320.1 - 8.4e-24 84.6 6.1 8.4e-24 84.6 6.1 1.7 1 1 1 2 2 2 1 Tetraspanin family EI24 PF07264.11 PVD23320.1 - 0.02 15.2 3.0 0.038 14.2 3.0 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Saf_2TM PF18303.1 PVD23320.1 - 0.15 11.6 0.2 0.15 11.6 0.2 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2892 PF11127.8 PVD23320.1 - 0.91 9.6 13.2 0.09 12.8 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) DUF4064 PF13273.6 PVD23320.1 - 3.2 8.1 14.7 7.1 7.0 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) FtsX PF02687.21 PVD23320.1 - 9.8 6.7 12.8 9.7 6.7 6.5 2.3 1 1 1 2 2 2 0 FtsX-like permease family Tetraspanin PF00335.20 PVD23321.1 - 8.3e-27 94.4 20.6 2.3e-13 50.4 15.2 2.3 1 1 1 2 2 2 2 Tetraspanin family MDFI PF15316.6 PVD23321.1 - 0.088 12.9 0.0 0.088 12.9 0.0 3.0 4 1 0 4 4 4 0 MyoD family inhibitor Tetraspanin PF00335.20 PVD23324.1 - 2.1e-28 99.6 16.0 2e-15 57.1 0.4 2.0 1 1 1 2 2 2 2 Tetraspanin family Shisa PF13908.6 PVD23324.1 - 0.52 10.5 4.6 0.099 12.9 0.5 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ribosomal_L7Ae PF01248.26 PVD23325.1 - 0.00036 20.2 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-B_box PF00643.24 PVD23326.1 - 4.7e-10 39.5 23.3 4.5e-09 36.3 7.6 3.8 4 1 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD23326.1 - 6.5e-09 35.7 6.2 6.5e-09 35.7 6.2 3.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD23326.1 - 1e-06 28.5 11.1 1e-06 28.5 11.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD23326.1 - 1.2e-05 25.0 2.5 1.2e-05 25.0 2.5 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD23326.1 - 2.4e-05 24.6 11.0 2.4e-05 24.6 11.0 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD23326.1 - 0.00015 21.5 8.4 0.00015 21.5 8.4 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD23326.1 - 0.00067 19.6 10.4 0.00067 19.6 10.4 4.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD23326.1 - 0.00095 19.3 12.2 0.00095 19.3 12.2 3.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD23326.1 - 0.0058 16.5 8.3 0.0058 16.5 8.3 3.8 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 ANAPC4 PF12896.7 PVD23326.1 - 0.11 12.0 0.2 0.3 10.5 0.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 zf-RING_11 PF17123.5 PVD23326.1 - 0.12 12.2 7.3 0.39 10.5 7.3 2.0 1 0 0 1 1 1 0 RING-like zinc finger DUF1664 PF07889.12 PVD23326.1 - 0.12 12.5 6.0 0.28 11.2 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Reeler PF02014.16 PVD23327.1 - 1e-20 74.8 0.1 2e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 PVD23327.1 - 1.1e-10 41.9 0.3 1.1e-10 41.9 0.3 2.0 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 PVD23327.1 - 1.1e-08 35.3 2.6 2e-08 34.4 2.6 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 QueT PF06177.11 PVD23327.1 - 0.27 11.6 6.5 4.9 7.5 0.4 2.4 2 0 0 2 2 2 0 QueT transporter Laminin_G_1 PF00054.23 PVD23328.1 - 2.8e-74 247.6 0.2 3.8e-28 98.3 0.0 3.1 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 PVD23328.1 - 5.6e-70 233.8 2.2 1.5e-26 93.5 0.1 3.1 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 PVD23328.1 - 3.4e-11 43.5 0.7 0.02 15.1 0.1 3.2 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD23328.1 - 0.00075 19.7 18.8 0.009 16.3 7.8 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 PVD23328.1 - 0.0053 17.3 2.3 0.0053 17.3 2.3 3.3 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 PVD23328.1 - 5 7.6 22.2 0.35 11.3 8.0 2.7 2 1 0 2 2 2 0 EGF-like domain COesterase PF00135.28 PVD23329.1 - 3.9e-79 266.9 0.0 6.1e-72 243.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family PAF-AH_p_II PF03403.13 PVD23329.1 - 0.16 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II COesterase PF00135.28 PVD23330.1 - 2e-135 452.6 0.0 2.3e-135 452.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23330.1 - 2.1e-10 40.8 0.3 1.5e-09 38.0 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD23330.1 - 0.00014 22.6 0.8 0.00048 20.8 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PVD23330.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 PVD23331.1 - 7.4e-132 440.8 0.0 8.5e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23331.1 - 3.9e-10 39.9 0.3 2.3e-09 37.4 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD23331.1 - 0.00088 19.9 0.2 0.0029 18.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PVD23331.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 PVD23332.1 - 3.8e-117 392.3 0.0 7.3e-104 348.5 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23332.1 - 1.5e-05 25.0 0.5 0.00012 22.0 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 PVD23332.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF3864 PF12980.7 PVD23332.1 - 0.14 12.5 0.3 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) COesterase PF00135.28 PVD23333.1 - 1.7e-136 456.1 0.0 1.9e-136 455.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23333.1 - 2.6e-06 27.4 0.2 2.3e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD23334.1 - 1.3e-24 87.0 0.0 1.6e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family SwrA PF17423.2 PVD23334.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Swarming motility protein COesterase PF00135.28 PVD23335.1 - 1.5e-83 281.4 0.0 8.7e-51 173.3 0.0 3.0 1 1 1 3 3 3 3 Carboxylesterase family COesterase PF00135.28 PVD23336.1 - 6.2e-113 378.4 0.0 3.5e-69 234.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23336.1 - 0.03 14.2 0.1 0.13 12.1 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 PVD23337.1 - 6.7e-26 91.2 0.0 7.8e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family 2-oxogl_dehyd_N PF16078.5 PVD23337.1 - 0.089 12.4 0.2 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus COesterase PF00135.28 PVD23338.1 - 1e-93 314.9 0.0 1.3e-93 314.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23338.1 - 1.5e-07 31.5 0.4 1.6e-06 28.1 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD23338.1 - 7.4e-06 26.7 1.7 0.00073 20.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2920 PF11144.8 PVD23338.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) COesterase PF00135.28 PVD23339.1 - 4.9e-144 481.0 0.0 5.6e-144 480.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD23339.1 - 3.3e-07 30.4 0.6 2.5e-06 27.5 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold MT PF12777.7 PVD23340.1 - 0.00023 20.3 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Acyltransferase PF01553.21 PVD23341.1 - 6.8e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 PVD23341.1 - 0.00012 21.1 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RPAP2_Rtr1 PF04181.13 PVD23342.1 - 5.1e-23 81.2 1.7 1.7e-22 79.5 1.7 2.0 1 0 0 1 1 1 1 Rtr1/RPAP2 family VPS28 PF03997.12 PVD23343.1 - 4.6e-71 238.4 0.5 5.3e-71 238.2 0.5 1.0 1 0 0 1 1 1 1 VPS28 protein DUF1128 PF06569.11 PVD23343.1 - 0.1 12.6 0.3 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Sulfotransfer_2 PF03567.14 PVD23344.1 - 6.3e-24 85.2 1.9 5e-21 75.8 1.9 2.8 1 1 0 1 1 1 1 Sulfotransferase family TFIIF_alpha PF05793.12 PVD23345.1 - 0.76 8.3 39.7 0.87 8.1 39.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 PVD23345.1 - 1.4 7.6 19.7 1.6 7.4 19.7 1.3 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 PVD23345.1 - 4 7.3 31.8 4.6 7.1 31.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Membralin PF09746.9 PVD23345.1 - 6.1 5.8 12.6 7.3 5.5 12.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein CCDC24 PF15669.5 PVD23346.1 - 7.7e-44 150.0 1.7 7.7e-44 150.0 1.7 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family KI67R PF08065.12 PVD23346.1 - 0.0077 16.8 0.4 0.029 14.9 0.4 2.0 1 0 0 1 1 1 1 KI67R (NUC007) repeat Linker_histone PF00538.19 PVD23347.1 - 0.0003 21.1 0.0 0.00047 20.5 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family ADIP PF11559.8 PVD23348.1 - 6.2e-11 42.6 17.0 6.2e-11 42.6 17.0 2.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding PI_PP_I PF18363.1 PVD23348.1 - 0.038 14.2 2.0 0.093 12.9 0.8 2.3 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Galactosyl_T PF01762.21 PVD23349.1 - 2.7e-42 144.8 0.0 4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD23349.1 - 4.4e-05 23.1 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like TRAM1 PF08390.11 PVD23349.1 - 0.28 10.9 1.3 0.77 9.5 1.3 1.7 1 0 0 1 1 1 0 TRAM1-like protein Patched PF02460.18 PVD23350.1 - 3e-84 283.6 10.2 3.7e-84 283.3 10.2 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD23350.1 - 3.3e-15 56.3 10.5 3.3e-15 56.3 10.5 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NGP1NT PF08153.12 PVD23351.1 - 9e-46 155.2 0.1 9e-46 155.2 0.1 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 PVD23351.1 - 3.3e-17 62.6 1.1 2.2e-13 50.3 0.0 3.3 3 1 1 4 4 4 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD23351.1 - 1.7e-06 27.7 0.2 6.3e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD23351.1 - 0.00023 21.1 0.0 0.001 19.0 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 PVD23351.1 - 0.0019 17.9 0.0 0.0065 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 PVD23351.1 - 0.027 13.9 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 PVD23351.1 - 0.87 9.6 8.9 3.6 7.6 0.1 4.3 3 2 1 4 4 4 0 Dynamin family Thioredoxin_8 PF13905.6 PVD23352.1 - 5.9e-08 32.9 0.1 4e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like DUF536 PF04394.14 PVD23352.1 - 0.012 15.5 1.7 0.021 14.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF536 IF-2B PF01008.17 PVD23353.1 - 1.1e-82 277.5 0.2 1.4e-82 277.1 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phospholip_A2_3 PF09056.11 PVD23354.1 - 0.079 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Herpes_UL14 PF03580.14 PVD23355.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Filament_head PF04732.14 PVD23355.1 - 0.6 11.0 8.9 1.3 9.9 5.3 2.9 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region Pkinase PF00069.25 PVD23356.1 - 9.2e-64 215.3 0.0 1.4e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23356.1 - 1.8e-39 135.6 0.0 3.4e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD23356.1 - 5.9e-05 22.5 0.0 0.095 12.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PVD23356.1 - 0.00048 19.0 0.0 0.00048 19.0 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase SWIM PF04434.17 PVD23356.1 - 0.004 16.8 0.1 0.004 16.8 0.1 2.6 3 0 0 3 3 3 1 SWIM zinc finger Ribosomal_L39 PF00832.20 PVD23356.1 - 0.52 10.0 1.7 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L39 protein AhpC-TSA PF00578.21 PVD23357.1 - 3e-39 133.8 0.0 4e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PVD23357.1 - 1.5e-14 53.9 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PVD23357.1 - 1.2e-12 47.4 0.1 2.1e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PMP22_Claudin PF00822.20 PVD23358.1 - 0.00023 21.1 8.1 0.00043 20.2 7.3 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD23358.1 - 0.00063 19.7 13.3 0.00088 19.3 13.3 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 PVD23358.1 - 0.11 12.2 17.8 0.19 11.5 11.3 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_2 PF13903.6 PVD23359.1 - 0.07 12.9 15.3 0.58 9.9 15.3 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SAS-6_N PF16531.5 PVD23360.1 - 4.6e-27 94.4 0.7 2e-26 92.4 0.7 2.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Profilin PF00235.19 PVD23360.1 - 1.1e-17 64.5 0.0 2.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Profilin Sas6_CC PF18594.1 PVD23360.1 - 2.4e-13 49.6 5.4 2.4e-13 49.6 5.4 3.7 3 0 0 3 3 3 1 Sas6/XLF/XRCC4 coiled-coil domain Spc7 PF08317.11 PVD23360.1 - 0.12 11.3 70.7 0.6 8.9 20.7 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.6 PVD23360.1 - 0.53 8.9 53.6 2.6 6.6 32.2 2.1 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.8 PVD23360.1 - 0.66 7.4 65.1 1.1 6.6 28.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 PVD23360.1 - 1.1 9.3 41.3 0.34 11.0 8.9 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD23360.1 - 1.3 8.8 55.7 3.2 7.6 14.2 2.7 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PMEI PF04043.15 PVD23360.1 - 2.7 8.3 13.1 1.6 9.1 0.2 3.4 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor ATG16 PF08614.11 PVD23360.1 - 5.2 7.2 75.8 0.23 11.7 15.1 4.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Zf_RING PF16744.5 PVD23361.1 - 3.1e-16 59.3 10.3 3.1e-16 59.3 10.3 2.3 2 1 0 2 2 2 1 KIAA1045 RING finger EF-hand_7 PF13499.6 PVD23361.1 - 4.4e-07 30.3 0.1 0.096 13.2 0.1 3.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD23361.1 - 4.3e-05 23.1 0.0 0.63 10.1 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain PHD PF00628.29 PVD23361.1 - 0.0086 16.0 11.7 0.0086 16.0 11.7 2.4 2 0 0 2 2 2 1 PHD-finger HIPIP PF01355.17 PVD23361.1 - 0.017 15.4 0.8 0.083 13.2 0.8 2.2 1 0 0 1 1 1 0 High potential iron-sulfur protein Zn_ribbon_17 PF17120.5 PVD23361.1 - 0.091 12.4 9.6 0.37 10.4 9.6 2.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 PVD23361.1 - 0.11 12.4 10.3 0.033 14.1 5.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3079 PF11278.8 PVD23361.1 - 0.85 9.5 5.9 0.14 12.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) PHD_4 PF16866.5 PVD23361.1 - 2.5 8.3 14.5 0.3 11.2 8.8 2.5 2 0 0 2 2 2 0 PHD-finger zf-B_box PF00643.24 PVD23362.1 - 5.1e-10 39.3 2.3 1.2e-09 38.1 2.3 1.6 1 0 0 1 1 1 1 B-box zinc finger Reg_prop PF07494.11 PVD23362.1 - 0.00064 19.6 0.2 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Two component regulator propeller PIN_8 PF18476.1 PVD23362.1 - 0.013 15.4 0.7 0.019 14.8 0.7 1.2 1 0 0 1 1 1 0 PIN like domain SKA2 PF16740.5 PVD23362.1 - 0.04 13.7 1.7 0.073 12.9 1.7 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Rx_N PF18052.1 PVD23362.1 - 2.2 8.6 6.2 4.4 7.7 5.3 1.8 1 1 1 2 2 2 0 Rx N-terminal domain DUF4032 PF13224.6 PVD23363.1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) DUF621 PF04789.15 PVD23363.1 - 0.027 13.6 0.1 3 6.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF621) BACK PF07707.15 PVD23363.1 - 0.043 13.9 0.3 5.3 7.2 0.0 2.2 1 1 1 2 2 2 0 BTB And C-terminal Kelch CABIT PF12736.7 PVD23364.1 - 1.6e-17 63.7 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 PVD23364.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ald_Xan_dh_C2 PF02738.18 PVD23365.1 - 3.5e-125 418.6 0.2 4.2e-98 329.2 0.1 2.1 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase CO_deh_flav_C PF03450.17 PVD23365.1 - 1.8e-24 85.9 0.0 8.6e-24 83.7 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 PVD23365.1 - 8.3e-22 77.6 0.1 2.2e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PVD23365.1 - 1.1e-11 44.7 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CABIT PF12736.7 PVD23366.1 - 2.4e-16 59.9 0.3 6.3e-16 58.5 0.3 1.7 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, CABIT PF12736.7 PVD23367.1 - 1e-28 100.5 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, zf-C4H2 PF10146.9 PVD23368.1 - 0.17 12.1 2.7 0.24 11.7 2.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein SUIM_assoc PF16619.5 PVD23368.1 - 1.5 9.0 13.4 1.9 8.6 6.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sporozoite_P67 PF05642.11 PVD23368.1 - 2 6.4 7.9 2.3 6.2 7.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Integrase_H2C2 PF17921.1 PVD23374.1 - 7e-06 26.1 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF962 PF06127.11 PVD23377.1 - 0.093 12.8 0.4 0.4 10.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF962) CABIT PF12736.7 PVD23379.1 - 3.6e-13 49.5 0.2 1.1e-09 38.1 0.1 2.8 2 1 0 2 2 2 2 Cell-cycle sustaining, positive selection, JHY PF15261.6 PVD23379.1 - 0.047 14.4 1.0 0.18 12.5 1.0 2.0 1 0 0 1 1 1 0 Jhy protein DUF1232 PF06803.12 PVD23381.1 - 2.1e-11 43.4 11.7 5e-11 42.2 11.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) HOOK PF05622.12 PVD23382.1 - 3.3e-243 809.0 79.0 3.9e-243 808.7 79.0 1.0 1 0 0 1 1 1 1 HOOK protein CH_2 PF06294.11 PVD23382.1 - 0.0087 16.2 1.2 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 CH-like domain in sperm protein TMF_TATA_bd PF12325.8 PVD23382.1 - 0.01 16.1 6.7 0.01 16.1 6.7 7.4 2 2 6 8 8 8 2 TATA element modulatory factor 1 TATA binding SLED PF12140.8 PVD23382.1 - 0.29 11.7 3.6 0.43 11.1 0.2 3.0 2 0 0 2 2 2 0 SLED domain Prominin PF05478.11 PVD23383.1 - 9.2e-05 20.6 2.5 9.2e-05 20.6 2.5 1.7 2 0 0 2 2 2 1 Prominin FH2 PF02181.23 PVD23383.1 - 0.00024 20.4 3.1 0.83 8.7 0.2 3.2 2 1 1 3 3 3 1 Formin Homology 2 Domain V-SNARE PF05008.15 PVD23383.1 - 0.00095 19.5 4.3 0.0038 17.6 0.1 3.2 4 0 0 4 4 2 1 Vesicle transport v-SNARE protein N-terminus Cep57_CLD_2 PF14197.6 PVD23383.1 - 0.0043 17.1 12.0 0.016 15.3 4.3 3.6 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 DUF4482 PF14818.6 PVD23383.1 - 0.0067 17.3 6.6 0.023 15.6 5.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4482) DUF1664 PF07889.12 PVD23383.1 - 0.0097 15.9 12.4 2 8.5 3.7 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1664) WXG100 PF06013.12 PVD23383.1 - 0.012 15.8 4.2 0.14 12.4 0.4 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.9 PVD23383.1 - 0.017 15.4 7.1 5.4 7.4 0.6 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 PVD23383.1 - 0.026 15.1 11.5 7.4 7.2 0.0 4.8 3 1 2 5 5 5 0 Bone marrow stromal antigen 2 Trimer_CC PF08954.11 PVD23383.1 - 0.032 13.8 1.3 6.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Trimerisation motif Laminin_II PF06009.12 PVD23383.1 - 0.048 13.7 9.9 1.9 8.5 0.2 3.4 3 0 0 3 3 3 0 Laminin Domain II DUF4618 PF15397.6 PVD23383.1 - 0.051 13.0 9.8 0.47 9.8 0.7 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 PVD23383.1 - 0.062 13.7 11.7 0.36 11.2 1.9 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 PVD23383.1 - 0.076 13.3 4.7 2.9 8.2 0.2 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 PVD23383.1 - 0.095 12.7 8.8 0.13 12.2 0.7 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 PVD23383.1 - 0.1 13.1 7.8 2 8.9 7.7 2.7 2 1 0 2 2 1 0 Apg6 coiled-coil region DUF677 PF05055.12 PVD23383.1 - 0.11 11.3 4.6 0.061 12.2 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF677) CdvA PF18822.1 PVD23383.1 - 0.13 12.1 8.9 0.46 10.3 2.0 3.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain NPV_P10 PF05531.12 PVD23383.1 - 0.19 12.2 9.9 22 5.6 0.3 4.5 4 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DASH_Dad1 PF08649.10 PVD23383.1 - 0.27 11.4 5.1 0.84 9.9 0.6 3.2 3 1 0 3 3 2 0 DASH complex subunit Dad1 Vps52 PF04129.12 PVD23383.1 - 0.28 9.9 4.6 0.21 10.3 1.1 2.0 1 1 0 2 2 2 0 Vps52 / Sac2 family DUF812 PF05667.11 PVD23383.1 - 0.29 10.0 8.9 2 7.2 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ApoLp-III PF07464.11 PVD23383.1 - 0.37 10.9 5.4 5.5 7.1 0.3 3.5 3 1 1 4 4 3 0 Apolipophorin-III precursor (apoLp-III) DUF3450 PF11932.8 PVD23383.1 - 0.42 9.9 14.3 0.54 9.5 5.6 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.6 PVD23383.1 - 0.46 10.9 11.0 2.3 8.6 0.9 3.5 2 1 1 3 3 3 0 Syntaxin-like protein FUSC PF04632.12 PVD23383.1 - 0.48 8.9 2.3 0.66 8.4 2.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cluap1 PF10234.9 PVD23383.1 - 0.58 9.5 8.7 26 4.1 8.7 2.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 PilO PF04350.13 PVD23383.1 - 0.58 10.3 5.1 39 4.4 0.0 3.3 3 0 0 3 3 3 0 Pilus assembly protein, PilO Arm-DNA-bind_5 PF17293.2 PVD23383.1 - 0.59 10.6 3.9 2 8.9 0.1 2.9 3 0 0 3 3 2 0 Arm DNA-binding domain SlyX PF04102.12 PVD23383.1 - 0.66 10.6 15.5 11 6.7 1.6 4.2 3 1 1 4 4 4 0 SlyX Atg14 PF10186.9 PVD23383.1 - 0.76 8.8 10.3 0.86 8.6 8.0 2.1 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 PVD23383.1 - 0.84 9.7 13.3 0.28 11.2 1.5 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 PVD23383.1 - 0.95 9.6 15.5 2.2 8.5 7.4 3.9 4 1 1 5 5 3 0 Fibrinogen alpha/beta chain family FAP206 PF12018.8 PVD23383.1 - 0.98 8.9 3.8 2.7 7.4 2.9 2.2 2 1 0 2 2 2 0 Domain of unknown function PilJ PF13675.6 PVD23383.1 - 1 9.4 5.6 15 5.7 0.1 3.3 3 1 1 4 4 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Occludin_ELL PF07303.13 PVD23383.1 - 1.1 10.0 7.1 6.5 7.5 0.7 3.6 2 1 0 3 3 3 0 Occludin homology domain DivIC PF04977.15 PVD23383.1 - 1.1 9.0 12.6 0.14 12.0 1.7 3.5 4 0 0 4 4 3 0 Septum formation initiator UPF0242 PF06785.11 PVD23383.1 - 1.2 9.2 6.6 1.9 8.6 5.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS6_N PF14661.6 PVD23383.1 - 1.2 8.6 9.4 34 3.9 9.4 2.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CCDC-167 PF15188.6 PVD23383.1 - 1.3 9.4 10.1 9.9 6.6 0.4 4.0 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Apolipoprotein PF01442.18 PVD23383.1 - 1.3 8.9 11.8 2.7 7.8 10.1 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 PVD23383.1 - 1.4 9.4 7.6 50 4.4 0.2 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) SOGA PF11365.8 PVD23383.1 - 1.5 10.0 10.1 0.11 13.7 2.4 2.7 2 1 1 3 3 2 0 Protein SOGA zf-C4H2 PF10146.9 PVD23383.1 - 1.9 8.8 12.3 17 5.6 12.3 2.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF2730 PF10805.8 PVD23383.1 - 1.9 8.6 9.0 25 5.0 0.2 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) DUF883 PF05957.13 PVD23383.1 - 2.1 9.0 7.4 20 5.9 0.2 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4446 PF14584.6 PVD23383.1 - 2.3 8.2 5.2 9.8 6.1 0.5 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4446) ATG16 PF08614.11 PVD23383.1 - 2.3 8.4 16.3 12 6.1 13.2 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FliT PF05400.13 PVD23383.1 - 2.9 8.8 8.8 50 4.8 0.1 3.0 2 1 0 2 2 2 0 Flagellar protein FliT DUF5082 PF16888.5 PVD23383.1 - 3.1 8.1 15.6 9.3 6.5 0.5 4.5 3 1 2 5 5 4 0 Domain of unknown function (DUF5082) CorA PF01544.18 PVD23383.1 - 5.1 6.3 12.0 9.5 5.4 8.0 2.5 3 0 0 3 3 2 0 CorA-like Mg2+ transporter protein CENP-Q PF13094.6 PVD23383.1 - 5.9 7.1 16.6 0.83 9.8 7.8 2.7 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.9 PVD23383.1 - 7.7 6.8 10.2 10 6.4 1.7 3.9 3 0 0 3 3 3 0 Haemolysin XhlA DUF4349 PF14257.6 PVD23383.1 - 9.1 5.7 10.4 1.4 8.3 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) TIR PF01582.20 PVD23385.1 - 1.8e-30 106.0 0.1 2.7e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD23385.1 - 3.2e-21 76.1 0.1 8.3e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 TIR domain EGF_2 PF07974.13 PVD23385.1 - 0.00011 22.4 23.5 0.021 15.2 4.8 2.6 1 1 1 2 2 2 2 EGF-like domain DegS PF05384.11 PVD23385.1 - 0.0029 17.1 0.2 0.0052 16.3 0.2 1.4 1 0 0 1 1 1 1 Sensor protein DegS EGF PF00008.27 PVD23385.1 - 0.016 15.5 0.4 0.016 15.5 0.4 2.6 2 0 0 2 2 2 0 EGF-like domain DUF4381 PF14316.6 PVD23385.1 - 0.033 14.4 0.3 0.056 13.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1863 PF08937.11 PVD23385.1 - 0.034 14.5 0.5 0.16 12.3 0.5 2.1 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) EGF_3 PF12947.7 PVD23385.1 - 0.26 11.5 18.1 1.4 9.2 3.3 2.6 1 1 1 2 2 2 0 EGF domain Laminin_EGF PF00053.24 PVD23385.1 - 0.42 10.8 15.6 4.2 7.6 5.3 2.6 1 1 1 2 2 2 0 Laminin EGF domain Toxin_3 PF00537.18 PVD23385.1 - 9.1 6.6 17.2 26 5.1 17.2 1.8 1 0 0 1 1 1 0 Scorpion toxin-like domain Acyl-CoA_dh_1 PF00441.24 PVD23387.1 - 2.2e-28 99.4 0.1 3e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PVD23387.1 - 9e-21 73.9 0.0 1.4e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD23387.1 - 2.4e-20 73.3 0.1 4.8e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD23387.1 - 5.2e-06 26.8 0.1 1e-05 25.8 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NUC153 PF08159.12 PVD23388.1 - 8.7e-14 51.0 2.7 2.2e-13 49.7 2.7 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 PVD23388.1 - 0.00021 22.0 0.0 3.8 8.5 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Receptor_IA-2 PF11548.8 PVD23388.1 - 0.16 12.0 0.4 0.42 10.6 0.4 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 PI3K_1B_p101 PF10486.9 PVD23388.1 - 3.7 5.2 11.8 5.1 4.8 11.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mtp PF03821.16 PVD23389.1 - 1.5e-16 60.7 4.2 6.2e-10 39.1 0.2 2.0 1 1 0 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 PVD23389.1 - 0.018 15.7 6.2 1 10.0 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) FliG_N PF14842.6 PVD23390.1 - 0.0071 16.9 1.2 0.64 10.6 1.2 2.5 1 1 0 1 1 1 1 FliG N-terminal domain Pertus-S5-tox PF09276.10 PVD23390.1 - 0.031 14.3 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Pertussis toxin S5 subunit p450 PF00067.22 PVD23391.1 - 1.4e-88 297.6 0.3 3.6e-69 233.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Acetyltransf_5 PF13444.6 PVD23392.1 - 0.2 12.4 3.1 2.7 8.7 0.4 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC_transp_aux PF09822.9 PVD23394.1 - 2.8e-08 33.5 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system ThuA PF06283.11 PVD23394.1 - 0.1 12.8 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Trehalose utilisation DDOST_48kD PF03345.14 PVD23394.1 - 0.15 10.9 0.0 2.7 6.7 0.0 2.1 1 1 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 PVD23395.1 - 2.5e-69 233.6 0.0 3.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23395.1 - 5e-34 117.8 0.0 6.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 PVD23395.1 - 6.4e-09 35.8 0.2 1.4e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 PVD23395.1 - 2.1e-07 30.5 0.0 4.6e-07 29.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 PVD23395.1 - 0.00024 20.8 0.0 0.062 12.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 PVD23395.1 - 0.00034 21.3 0.1 0.0061 17.2 0.0 2.8 3 0 0 3 3 3 1 Protein kinase C terminal domain Kdo PF06293.14 PVD23395.1 - 0.0083 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD23395.1 - 0.18 10.7 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF5572 PF17733.1 PVD23396.1 - 1.2e-11 44.3 0.1 1.9e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) zf-C2H2_4 PF13894.6 PVD23397.1 - 1.7e-17 62.6 73.5 0.0014 19.3 2.1 10.6 11 0 0 11 11 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD23397.1 - 2.9e-13 49.5 79.4 0.00093 19.5 2.7 10.5 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD23397.1 - 2.6e-10 40.3 60.5 0.00041 20.6 0.6 9.3 9 0 0 9 9 9 5 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 PVD23397.1 - 0.00064 19.3 0.6 0.00064 19.3 0.6 5.3 5 0 0 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 PVD23397.1 - 0.0011 19.3 59.8 0.039 14.3 0.4 9.4 11 0 0 11 11 9 7 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 PVD23397.1 - 0.0024 18.6 3.5 0.0024 18.6 3.5 5.6 4 1 2 6 6 6 1 zinc-ribbon family RBR PF17208.3 PVD23397.1 - 0.14 12.9 6.0 0.2 12.4 3.6 2.7 2 0 0 2 2 1 0 RNA binding Region zf-C2HC_2 PF13913.6 PVD23397.1 - 0.8 9.7 15.9 0.25 11.3 0.3 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 PVD23397.1 - 1.3 9.4 47.3 1.9 8.9 9.0 7.7 4 1 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PVD23397.1 - 2.8 8.4 56.6 0.53 10.6 1.1 9.0 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 PVD23397.1 - 6.1 6.8 13.6 31 4.6 0.1 5.6 6 0 0 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Y_phosphatase PF00102.27 PVD23399.1 - 4.6e-166 550.0 0.5 3.5e-83 278.8 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 PVD23399.1 - 2.6e-125 409.1 35.8 7.8e-16 58.2 0.1 10.7 10 0 0 10 10 10 9 Fibronectin type III domain Ig_3 PF13927.6 PVD23399.1 - 1.1e-41 141.3 1.2 2.6e-15 56.8 0.0 5.7 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 PVD23399.1 - 1.8e-40 136.9 0.0 2.1e-16 59.7 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 PVD23399.1 - 3.1e-30 104.6 26.1 5.6e-05 23.6 0.0 9.8 9 0 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 PVD23399.1 - 4.1e-23 81.5 0.2 2.4e-07 31.0 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD23399.1 - 1.1e-15 57.5 0.0 1.7e-05 24.9 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain Interfer-bind PF09294.10 PVD23399.1 - 1.9e-12 47.4 0.0 2.7 8.4 0.0 8.2 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 PVD23399.1 - 6.5e-12 45.4 0.0 0.019 15.1 0.0 7.7 9 0 0 9 9 8 2 Fibronectin type III domain DSPc PF00782.20 PVD23399.1 - 4.3e-08 33.0 0.0 0.002 18.0 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain fn3_4 PF16794.5 PVD23399.1 - 6.8e-07 29.2 10.1 0.22 11.4 0.1 8.0 9 2 0 9 9 8 1 Fibronectin-III type domain C2-set_2 PF08205.12 PVD23399.1 - 3e-06 27.2 0.0 0.081 13.0 0.0 3.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD23399.1 - 5.8e-06 26.4 0.2 0.22 11.7 0.0 5.2 3 2 0 3 3 3 1 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 PVD23399.1 - 1.1e-05 25.5 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD23399.1 - 8.3e-05 22.7 0.0 0.049 13.7 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Glyco_hydro_36C PF16874.5 PVD23399.1 - 0.0004 20.8 0.1 9.8 6.7 0.0 5.4 5 0 0 5 5 5 0 Glycosyl hydrolase family 36 C-terminal domain DUF2369 PF10179.9 PVD23399.1 - 0.0051 17.2 0.9 1.1e+02 3.3 0.0 5.6 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 PVD23399.1 - 0.0089 16.3 2.5 8.3 6.7 0.0 4.9 5 0 0 5 5 4 1 Carbohydrate binding domain Ig_C17orf99 PF17736.1 PVD23399.1 - 0.17 12.0 0.0 62 3.7 0.0 3.7 3 0 0 3 3 3 0 C17orf99 Ig domain DUF1410 PF07198.11 PVD23399.1 - 0.18 12.3 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) CAP PF00188.26 PVD23400.1 - 6e-08 33.6 0.5 7.7e-08 33.2 0.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ndufs5 PF10200.9 PVD23401.1 - 3.3e-09 36.9 1.1 4.6e-09 36.4 1.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 PVD23401.1 - 0.00048 20.3 5.6 0.00079 19.6 5.6 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 PVD23401.1 - 0.00053 20.1 2.8 0.00053 20.1 2.8 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 PVD23401.1 - 0.00054 19.9 4.8 0.0008 19.4 4.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PVD23401.1 - 0.0007 19.7 10.3 0.028 14.6 2.6 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 PVD23401.1 - 0.76 9.8 9.4 3.9 7.6 2.6 2.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HECT PF00632.25 PVD23402.1 - 1.9e-92 310.1 0.2 2.5e-92 309.7 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OAF PF14941.6 PVD23402.1 - 0.042 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, Out at first TP_methylase PF00590.20 PVD23403.1 - 1.8e-18 67.3 0.3 5.8e-18 65.6 0.3 1.8 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_kinase PF01513.21 PVD23404.1 - 1.1e-06 28.0 0.0 2.6e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Peptidase_S51 PF03575.17 PVD23404.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 DAGK_cat PF00781.24 PVD23404.1 - 0.042 13.5 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PTS_IIB PF02302.17 PVD23404.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit YqaJ PF09588.10 PVD23405.1 - 4.2e-11 43.2 0.0 1.3e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain CC2D2AN-C2 PF15625.6 PVD23406.1 - 1.8e-56 190.6 0.1 4.2e-56 189.4 0.1 1.7 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 PVD23406.1 - 0.00091 19.5 2.3 0.036 14.3 0.0 3.6 3 1 0 3 3 3 1 C2 domain MtaB PF12176.8 PVD23406.1 - 2.1 7.0 5.0 3.9 6.1 5.0 1.3 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Ank_2 PF12796.7 PVD23407.1 - 4.4e-82 270.7 32.6 1.1e-16 61.1 1.7 7.6 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD23407.1 - 2.1e-65 216.3 24.9 4.3e-10 39.9 0.1 10.5 6 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23407.1 - 3.9e-63 201.9 22.1 6.3e-05 23.1 0.0 15.6 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 PVD23407.1 - 3e-59 196.3 24.2 1.1e-06 28.7 0.0 13.7 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 PVD23407.1 - 2.7e-55 182.5 37.0 3e-06 27.4 0.0 15.7 13 2 2 15 15 15 12 Ankyrin repeat Ion_trans PF00520.31 PVD23407.1 - 3.2e-10 39.6 23.0 4.8e-10 39.1 23.0 1.3 1 0 0 1 1 1 1 Ion transport protein V-SNARE_C PF12352.8 PVD23407.1 - 0.015 15.6 0.2 0.033 14.5 0.2 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Ycf70 PF17382.2 PVD23407.1 - 6 7.3 7.4 1.4e+02 2.9 0.1 3.6 3 0 0 3 3 3 0 Uncharacterized Ycf70-like HMA PF00403.26 PVD23408.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain BACK PF07707.15 PVD23409.1 - 2e-25 88.9 2.0 3.6e-25 88.0 0.7 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 PVD23409.1 - 5.1e-09 36.1 4.0 0.096 13.0 0.0 4.6 2 1 2 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PVD23409.1 - 5.7e-08 32.9 0.0 0.019 15.2 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain BTB PF00651.31 PVD23409.1 - 7.9e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD23409.1 - 4.1e-06 26.3 12.2 0.0003 20.3 0.2 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 PVD23409.1 - 1.7e-05 24.6 3.0 0.72 9.9 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD23409.1 - 1.7e-05 24.7 0.6 0.49 10.4 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD23409.1 - 0.0027 17.6 0.4 0.74 9.9 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Pkinase PF00069.25 PVD23410.1 - 8.2e-44 149.9 0.1 1.3e-43 149.3 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23410.1 - 1.3e-27 96.8 0.1 7.5e-27 94.2 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD23410.1 - 1.3e-07 31.3 0.0 3e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD23410.1 - 0.00082 18.3 0.0 0.0044 15.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD23410.1 - 0.035 14.0 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD23410.1 - 0.073 12.4 0.4 0.18 11.2 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_8 PF17903.1 PVD23411.1 - 4.8e-31 106.7 0.0 1.1e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 PVD23411.1 - 0.0091 15.8 0.0 0.026 14.4 0.0 1.8 1 1 1 2 2 2 1 KH domain KH_4 PF13083.6 PVD23411.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 KH domain EF-hand_4 PF12763.7 PVD23413.1 - 2.1e-25 88.7 0.2 2.3e-10 40.3 0.0 3.9 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD23413.1 - 8.9e-10 37.4 0.0 0.023 14.2 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD23413.1 - 8e-07 29.4 0.5 0.00016 22.1 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD23413.1 - 3.5e-06 26.5 0.0 1.1 9.3 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain AKAP2_C PF15304.6 PVD23413.1 - 9.2e-05 21.9 5.3 9.2e-05 21.9 5.3 7.4 3 2 4 7 7 7 5 A-kinase anchor protein 2 C-terminus EF-hand_5 PF13202.6 PVD23413.1 - 0.0023 17.3 0.5 4.1 7.1 0.0 3.7 4 0 0 4 4 4 2 EF hand Ig_3 PF13927.6 PVD23414.1 - 2.4e-13 50.5 0.0 6.2e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD23414.1 - 9.2e-11 41.7 0.0 3.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD23414.1 - 3.4e-09 36.9 0.0 0.00041 20.6 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain CUB PF00431.20 PVD23414.1 - 5e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 CUB domain ig PF00047.25 PVD23414.1 - 1.2e-05 25.4 0.0 0.00069 19.7 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain EGF_2 PF07974.13 PVD23414.1 - 0.015 15.7 8.5 0.015 15.7 8.5 4.5 4 0 0 4 4 4 0 EGF-like domain EGF PF00008.27 PVD23414.1 - 0.53 10.6 35.3 0.11 12.8 7.7 4.6 4 0 0 4 4 4 0 EGF-like domain NAGLU PF05089.12 PVD23415.1 - 5.7e-144 479.1 3.3 9.7e-144 478.4 3.3 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 PVD23415.1 - 2.8e-68 230.3 7.7 3.1e-68 230.2 6.6 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 PVD23415.1 - 8.3e-22 76.8 0.0 1.6e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Y_phosphatase PF00102.27 PVD23416.1 - 2.7e-58 197.3 2.9 1e-50 172.5 0.9 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD23416.1 - 0.00039 20.5 0.3 0.0012 18.9 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD23416.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 PVD23416.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4934 PF16288.5 PVD23418.1 - 0.076 12.9 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) HLH PF00010.26 PVD23420.1 - 1.9e-17 63.0 0.7 2.9e-17 62.4 0.7 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 PVD23420.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain AvrPto PF11592.8 PVD23421.1 - 0.037 14.1 10.4 11 6.1 0.7 4.8 1 1 6 7 7 7 0 Central core of the bacterial effector protein AvrPto DUF5363 PF17320.2 PVD23421.1 - 0.047 13.6 4.9 1.5e+02 2.3 0.0 5.9 2 2 4 6 6 6 0 Family of unknown function (DUF5363) Hyd_WA PF06462.12 PVD23421.1 - 0.46 10.5 4.9 17 5.5 0.1 3.9 1 1 2 3 3 3 0 Propeller Skp1_POZ PF03931.15 PVD23422.1 - 3.6e-11 43.1 0.0 5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PTAC PF06130.12 PVD23422.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphate propanoyltransferase Glyoxalase PF00903.25 PVD23423.1 - 4.1e-07 30.2 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PVD23423.1 - 0.0028 17.9 0.0 0.0033 17.7 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PVD23423.1 - 0.0031 17.6 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Sua5_yciO_yrdC PF01300.18 PVD23424.1 - 3.3e-39 134.2 0.0 9.2e-33 113.2 0.0 2.3 2 0 0 2 2 2 2 Telomere recombination Biliv-reduc_cat PF09166.10 PVD23424.1 - 0.11 12.8 0.0 24 5.3 0.0 2.2 2 0 0 2 2 2 0 Biliverdin reductase, catalytic RPN6_C_helix PF18503.1 PVD23424.1 - 0.44 10.3 1.3 7.5 6.4 0.1 3.0 3 0 0 3 3 3 0 26S proteasome subunit RPN6 C-terminal helix domain Sua5_yciO_yrdC PF01300.18 PVD23425.1 - 2.6e-32 111.8 0.0 4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination AcrZ PF10766.9 PVD23425.1 - 0.07 12.7 0.8 0.43 10.2 0.8 2.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Sua5_yciO_yrdC PF01300.18 PVD23426.1 - 2.6e-23 82.5 0.0 4.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Gpr1_Fun34_YaaH PF01184.19 PVD23426.1 - 0.0042 16.7 18.8 0.0042 16.7 18.8 4.6 3 1 1 4 4 4 3 GPR1/FUN34/yaaH family MmgE_PrpD PF03972.14 PVD23427.1 - 5.3e-108 361.4 0.3 6.1e-108 361.2 0.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PhyH PF05721.13 PVD23428.1 - 0.0076 16.5 1.0 0.011 16.0 1.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Neurensin PF14927.6 PVD23429.1 - 8.2e-35 119.4 0.0 1.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF3784 PF12650.7 PVD23429.1 - 0.016 15.4 1.4 0.24 11.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) SHIPPO-rpt PF07004.12 PVD23430.1 - 0.0003 21.6 28.4 0.14 13.1 0.8 6.4 7 0 0 7 7 7 4 Sperm-tail PG-rich repeat Ribonuc_red_sm PF00268.21 PVD23431.1 - 1.4e-122 408.5 1.3 1.8e-122 408.2 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain IBR PF01485.21 PVD23432.1 - 1.9e-16 60.0 28.3 1.4e-11 44.5 9.9 5.2 3 2 1 5 5 5 2 IBR domain, a half RING-finger domain DEK_C PF08766.11 PVD23433.1 - 5.1e-16 58.3 0.5 1.6e-15 56.7 0.5 1.9 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 PVD23433.1 - 2.5e-07 30.3 0.0 8.2e-07 28.6 0.0 2.0 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 PVD23433.1 - 0.0035 17.2 2.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain ISK_Channel PF02060.15 PVD23434.1 - 0.00018 21.2 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel TPR_8 PF13181.6 PVD23435.1 - 5e-23 79.3 10.3 3.1e-05 23.9 0.0 9.6 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD23435.1 - 1.6e-20 71.5 8.1 0.00019 21.3 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23435.1 - 6.1e-20 70.1 16.3 0.00055 19.6 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 PVD23435.1 - 1e-18 67.3 8.0 2.4e-05 24.5 0.0 6.7 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23435.1 - 2.2e-17 63.3 6.3 3.6e-05 24.2 0.2 9.4 5 2 6 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD23435.1 - 1.5e-13 50.3 0.1 0.00026 21.6 0.0 8.8 8 2 2 10 10 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD23435.1 - 1.6e-11 43.4 1.4 6 7.1 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD23435.1 - 3.8e-10 39.9 14.2 7.8e-06 26.0 0.1 6.5 4 2 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD23435.1 - 4.1e-09 36.9 0.0 7.7e-05 23.3 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD23435.1 - 4.7e-08 33.1 0.4 1.1 9.4 0.0 5.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD23435.1 - 1.5e-07 31.0 9.8 0.12 12.1 0.0 6.8 8 1 1 9 9 9 2 TPR repeat TPR_6 PF13174.6 PVD23435.1 - 1.4e-06 28.5 10.8 0.022 15.4 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD23435.1 - 1.4e-06 27.7 0.7 0.077 12.2 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 PVD23435.1 - 8.4e-06 26.0 5.0 0.43 10.9 0.2 5.9 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD23435.1 - 0.00019 21.0 6.3 0.95 8.8 0.0 4.2 3 2 1 4 4 4 2 MalT-like TPR region HrpB1_HrpK PF09613.10 PVD23435.1 - 0.0055 16.4 2.2 8.6 6.0 0.0 4.7 5 0 0 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 PVD23435.1 - 0.0079 16.5 7.6 11 6.7 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD23435.1 - 0.028 14.3 6.7 25 4.9 0.0 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 PVD23435.1 - 0.034 14.2 2.6 12 6.1 0.1 4.7 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 5 Nop53 PF07767.11 PVD23435.1 - 0.84 9.0 14.8 1.8 7.9 14.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.6 PVD23435.1 - 1.5 9.3 16.6 4.1 7.8 16.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LZ_Tnp_IS66 PF13007.7 PVD23435.1 - 1.7 9.4 6.0 4.4 8.1 6.0 1.7 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Laminin_EGF PF00053.24 PVD23436.1 - 1.5e-169 550.1 433.3 3.3e-11 43.1 12.8 23.4 22 1 1 23 23 23 22 Laminin EGF domain Laminin_G_2 PF02210.24 PVD23436.1 - 9.3e-111 365.6 7.4 1.3e-29 103.4 0.9 6.2 5 1 1 6 6 6 5 Laminin G domain Laminin_G_1 PF00054.23 PVD23436.1 - 2.7e-104 344.6 4.1 2.1e-28 99.2 0.0 6.3 5 1 1 6 6 6 5 Laminin G domain Laminin_N PF00055.17 PVD23436.1 - 3.6e-75 252.6 0.0 3.6e-75 252.6 0.0 2.9 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 PVD23436.1 - 1.3e-33 115.8 0.1 3.9e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 PVD23436.1 - 5.7e-18 65.5 5.3 0.00033 20.8 0.0 5.9 6 0 0 6 6 6 4 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 PVD23436.1 - 0.00026 21.0 1.0 0.00026 21.0 1.0 5.5 2 1 3 6 6 6 1 Laminin Domain II DUF4572 PF15139.6 PVD23437.1 - 2.2e-67 226.8 6.5 2.5e-67 226.6 6.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) SDF PF00375.18 PVD23438.1 - 2.5e-128 428.4 21.2 3.2e-128 428.1 21.2 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Cation_ATPase_N PF00690.26 PVD23438.1 - 0.037 13.7 0.1 0.037 13.7 0.1 2.8 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus DUF1600 PF07667.11 PVD23438.1 - 0.94 9.7 5.0 0.25 11.6 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) SDF PF00375.18 PVD23439.1 - 1.6e-98 330.3 11.0 1.7e-54 185.4 9.9 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family Kinocilin PF15033.6 PVD23439.1 - 2.6 7.7 4.9 2.1 8.0 2.3 2.1 2 0 0 2 2 2 0 Kinocilin protein Ras PF00071.22 PVD23442.1 - 1.1e-47 161.6 0.0 1.4e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD23442.1 - 1.1e-17 64.4 0.0 3.1e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD23442.1 - 1.1e-06 28.6 0.4 0.0064 16.4 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 PVD23442.1 - 6.4e-06 25.7 0.0 9.3e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD23442.1 - 0.0004 20.4 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PVD23442.1 - 0.0052 16.2 1.1 0.049 13.1 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 PVD23442.1 - 0.0054 15.7 0.1 0.4 9.6 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 PVD23442.1 - 0.0079 15.7 0.0 0.024 14.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PVD23442.1 - 0.01 16.2 0.2 0.027 14.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PVD23442.1 - 0.015 15.5 0.4 0.45 10.8 0.2 2.8 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 PVD23442.1 - 0.023 14.2 0.1 0.12 11.9 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 PVD23442.1 - 0.056 13.2 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PVD23442.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain TUDOR PF00567.24 PVD23443.1 - 7.2e-279 907.5 0.2 2e-27 95.7 0.0 11.7 11 0 0 11 11 11 11 Tudor domain SMN PF06003.12 PVD23443.1 - 5.4e-22 78.3 4.6 0.0018 17.6 0.2 8.8 9 0 0 9 9 9 7 Survival motor neuron protein (SMN) Agenet PF05641.12 PVD23443.1 - 1.7e-16 60.4 16.8 0.021 15.3 0.1 11.3 12 0 0 12 12 12 5 Agenet domain DUF4537 PF15057.6 PVD23443.1 - 1.5e-14 54.0 0.1 1.3 9.0 0.0 9.6 11 0 0 11 11 11 4 Domain of unknown function (DUF4537) SAWADEE PF16719.5 PVD23443.1 - 2.4e-06 27.6 11.6 1.5 8.8 0.0 8.9 10 0 0 10 10 10 2 SAWADEE domain Tudor_FRX1 PF18336.1 PVD23443.1 - 7.7e-05 22.5 7.8 0.013 15.4 0.1 5.8 5 0 0 5 5 5 1 Fragile X mental retardation Tudor domain DUF1325 PF07039.11 PVD23443.1 - 0.0046 17.1 0.0 0.71 10.0 0.0 4.2 3 0 0 3 3 3 1 SGF29 tudor-like domain Spore_coat_CotO PF14153.6 PVD23443.1 - 0.02 14.8 0.5 6.2 6.7 0.0 4.8 5 0 0 5 5 5 0 Spore coat protein CotO Cu-oxidase PF00394.22 PVD23443.1 - 0.026 14.6 2.1 17 5.5 0.0 5.3 6 0 0 6 6 6 0 Multicopper oxidase SPOR PF05036.13 PVD23443.1 - 0.039 14.3 0.0 9.4 6.7 0.0 4.3 4 0 0 4 4 4 0 Sporulation related domain p450 PF00067.22 PVD23444.1 - 1.7e-57 195.2 0.0 1.1e-36 126.6 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD23445.1 - 1.5e-72 244.8 0.0 1.8e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytomega_TRL10 PF06084.11 PVD23445.1 - 0.12 12.4 0.3 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein AAA_23 PF13476.6 PVD23446.1 - 3.4e-14 53.8 0.4 3.4e-14 53.8 0.4 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 PVD23446.1 - 1.8e-13 50.4 0.4 2.4e-13 50.1 0.4 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PVD23446.1 - 7.5e-08 32.5 0.2 7.5e-08 32.5 0.2 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PVD23446.1 - 0.00035 20.3 0.1 0.00061 19.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD23446.1 - 0.00044 20.2 1.0 0.00046 20.1 0.3 1.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 PVD23446.1 - 0.021 15.3 0.3 0.042 14.4 0.3 1.6 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 PVD23446.1 - 0.058 12.7 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 PVD23446.1 - 0.07 12.4 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TRAP_alpha PF03896.16 PVD23446.1 - 0.14 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SMC_N PF02463.19 PVD23447.1 - 3e-06 26.8 14.1 3e-06 26.8 14.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain LURAP PF14854.6 PVD23447.1 - 0.012 15.6 1.7 0.19 11.7 0.2 3.5 2 1 0 2 2 2 0 Leucine rich adaptor protein IFRD_C PF04836.12 PVD23447.1 - 0.052 14.1 0.7 0.54 10.9 0.0 3.2 2 0 0 2 2 2 0 Interferon-related protein conserved region SbcCD_C PF13558.6 PVD23447.1 - 0.096 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Spc7 PF08317.11 PVD23447.1 - 0.14 11.0 82.3 0.027 13.4 17.7 5.4 2 2 3 5 5 5 0 Spc7 kinetochore protein Fez1 PF06818.15 PVD23447.1 - 0.47 10.9 74.9 0.14 12.6 22.9 4.8 2 2 2 4 4 4 0 Fez1 Laminin_II PF06009.12 PVD23447.1 - 0.55 10.3 48.8 0.042 13.9 2.6 6.7 2 2 5 7 7 7 0 Laminin Domain II Bacillus_HBL PF05791.11 PVD23447.1 - 2.5 7.9 43.0 3.6 7.4 3.0 6.5 4 2 4 8 8 8 0 Bacillus haemolytic enterotoxin (HBL) APG6_N PF17675.1 PVD23447.1 - 3.7 8.1 89.0 0.066 13.7 17.9 5.5 2 2 3 5 5 5 0 Apg6 coiled-coil region Laminin_I PF06008.14 PVD23447.1 - 5 6.7 63.3 0.074 12.7 4.3 4.6 3 2 1 4 4 4 0 Laminin Domain I AAA_13 PF13166.6 PVD23447.1 - 5.8 5.4 66.2 0.036 12.7 22.4 4.2 2 1 1 3 3 3 0 AAA domain DUF4407 PF14362.6 PVD23447.1 - 6.6 6.0 55.2 0.24 10.7 12.7 4.1 2 2 1 4 4 4 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PVD23447.1 - 7 6.7 47.1 2.5 8.1 1.5 6.8 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 PVD23447.1 - 7.3 4.0 68.5 2.1 5.8 25.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Homeodomain PF00046.29 PVD23448.1 - 2.1e-13 49.9 2.4 7.9e-13 48.0 2.4 2.1 1 0 0 1 1 1 1 Homeodomain HNF-1_N PF04814.13 PVD23448.1 - 4.2e-13 50.4 0.0 5.8e-12 46.6 0.0 2.7 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus LacI PF00356.21 PVD23448.1 - 0.001 18.8 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Homeobox_KN PF05920.11 PVD23448.1 - 0.0045 16.9 1.1 0.028 14.3 0.1 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 PVD23448.1 - 0.01 15.3 0.0 0.23 11.0 0.0 2.8 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez TIR_2 PF13676.6 PVD23449.1 - 1.6e-26 93.2 1.6 1e-12 48.7 0.0 4.1 3 1 0 3 3 3 3 TIR domain UPF0004 PF00919.20 PVD23449.1 - 4.8e-20 71.4 0.9 1.2e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PVD23449.1 - 1.5e-11 44.9 0.2 4.2e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 PVD23449.1 - 3.1e-08 33.5 0.0 6.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 TRAM domain SAM_2 PF07647.17 PVD23449.1 - 4.5e-08 33.1 0.1 1.2e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD23449.1 - 6.2e-06 26.6 0.4 3.8e-05 24.0 0.4 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TIR PF01582.20 PVD23449.1 - 0.002 17.9 0.2 0.62 9.8 0.2 2.6 2 0 0 2 2 2 1 TIR domain Endonuc-EcoRV PF09233.11 PVD23449.1 - 0.019 14.4 0.0 0.055 12.8 0.0 1.8 1 1 1 2 2 2 0 Restriction endonuclease EcoRV SEFIR PF08357.11 PVD23449.1 - 0.023 14.9 0.1 1.8 8.9 0.1 2.8 2 0 0 2 2 2 0 SEFIR domain Ish1 PF10281.9 PVD23449.1 - 0.048 14.0 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein XhlA PF10779.9 PVD23449.1 - 0.27 11.4 1.6 0.81 9.9 1.6 1.7 1 0 0 1 1 1 0 Haemolysin XhlA TMEM65 PF10507.9 PVD23450.1 - 1.5e-23 82.8 0.1 4.7e-23 81.2 0.1 1.7 1 1 0 1 1 1 1 Transmembrane protein 65 GPHR_N PF12537.8 PVD23450.1 - 0.24 11.5 0.9 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal CAS_CSE1 PF03378.15 PVD23451.1 - 1.7e-160 534.3 0.0 3.8e-160 533.2 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 PVD23451.1 - 3.9e-152 506.4 0.1 7e-152 505.5 0.1 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 PVD23451.1 - 2.2e-12 46.7 0.1 1e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 PVD23451.1 - 0.013 15.2 1.4 0.88 9.3 0.0 3.4 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 PVD23451.1 - 0.023 14.8 0.0 0.46 10.5 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein HC2 PF07382.11 PVD23452.1 - 0.025 14.7 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 LRRC37 PF15779.5 PVD23452.1 - 0.2 12.0 15.1 4 7.9 2.0 4.0 2 1 2 4 4 4 0 Leucine-rich repeat-containing protein 37 family Phage_TAC_7 PF10109.9 PVD23452.1 - 0.21 11.7 1.5 8.6 6.5 0.1 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 fn3 PF00041.21 PVD23452.1 - 1.1 9.7 10.2 8.4 6.8 1.2 3.0 2 1 0 2 2 2 0 Fibronectin type III domain Hormone_5 PF00184.17 PVD23457.1 - 0.0023 18.7 0.3 0.004 17.9 0.3 1.4 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain HMG_box PF00505.19 PVD23458.1 - 2.3e-26 92.0 1.4 4e-26 91.2 1.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD23458.1 - 6.1e-10 39.5 0.6 1.3e-09 38.5 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain RVT_1 PF00078.27 PVD23459.1 - 6.1e-39 133.8 0.0 9.7e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF2 PF05477.11 PVD23462.1 - 0.67 9.6 8.5 1.5e+02 1.9 8.5 2.8 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pkinase PF00069.25 PVD23463.1 - 5.5e-57 193.1 0.2 1e-56 192.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23463.1 - 1.8e-36 125.8 0.1 3.2e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD23463.1 - 4.8e-09 35.9 0.0 7.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD23463.1 - 7.1e-05 22.3 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD23463.1 - 0.0099 15.8 0.4 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PVD23463.1 - 0.048 13.2 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1096 PF06493.11 PVD23463.1 - 9.7 6.7 6.4 7.9 7.0 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1096) C2 PF00168.30 PVD23464.1 - 9.3e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF1771 PF08590.10 PVD23464.1 - 9.7 6.7 8.6 0.72 10.3 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) Amidohydro_3 PF07969.11 PVD23465.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase family FlxA PF14282.6 PVD23465.1 - 0.69 9.9 8.3 2.9 7.9 2.0 3.9 3 0 0 3 3 3 0 FlxA-like protein Methyltransf_22 PF13383.6 PVD23466.1 - 8.3e-24 84.5 0.7 1.1e-23 84.2 0.7 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD23466.1 - 1.1e-07 32.0 0.1 1.5e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4835 PF16119.5 PVD23466.1 - 0.047 12.8 0.1 0.084 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Methyltransf_22 PF13383.6 PVD23467.1 - 7.2e-23 81.4 0.1 9e-23 81.1 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD23467.1 - 1.1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PVD23468.1 - 4.1e-16 59.3 0.8 4.9e-16 59.1 0.8 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_22 PF13383.6 PVD23469.1 - 7.9e-44 150.1 5.3 2.6e-22 79.6 0.5 2.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 PVD23469.1 - 1.2e-12 48.2 0.3 3.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase FkbM domain DUF4835 PF16119.5 PVD23469.1 - 0.00012 21.3 1.2 0.18 10.9 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4835) GatB_Yqey PF02637.18 PVD23469.1 - 0.0013 18.6 0.4 1.1 9.1 0.1 2.2 2 0 0 2 2 2 2 GatB domain Lge1 PF11488.8 PVD23469.1 - 0.0064 16.7 0.2 2.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Transcriptional regulatory protein LGE1 DUF4162 PF13732.6 PVD23469.1 - 0.022 15.5 1.2 2.5 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) LIP1 PF15904.5 PVD23469.1 - 0.025 14.9 0.2 15 6.0 0.0 3.2 4 0 0 4 4 4 0 LKB1 serine/threonine kinase interacting protein 1 Pro_3_hydrox_C PF05373.11 PVD23469.1 - 0.24 11.5 1.3 15 5.8 0.1 2.5 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Methyltransf_22 PF13383.6 PVD23470.1 - 5.1e-32 111.4 8.9 5.5e-22 78.5 1.3 2.0 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 PVD23470.1 - 1.4e-07 31.7 0.2 3.1e-07 30.6 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF4835 PF16119.5 PVD23470.1 - 0.056 12.5 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) SNAP-25 PF00835.19 PVD23471.1 - 0.02 15.2 1.6 0.74 10.2 0.0 2.7 2 1 0 2 2 2 0 SNAP-25 family G0-G1_switch_2 PF15103.6 PVD23471.1 - 1.7 9.1 5.3 3.6 8.1 0.0 2.6 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF5428 PF17493.2 PVD23471.1 - 3.3 8.2 6.5 0.72 10.3 2.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5428) CD225 PF04505.12 PVD23472.1 - 8.7e-21 73.8 1.9 1.2e-20 73.4 1.9 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4013 PF13197.6 PVD23472.1 - 0.002 18.0 0.2 0.0024 17.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF3188 PF11384.8 PVD23472.1 - 0.002 17.8 2.2 1.5 8.6 0.7 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF3188) SfLAP PF11139.8 PVD23472.1 - 0.012 15.1 0.7 0.016 14.6 0.7 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein AgrB PF04647.15 PVD23472.1 - 0.026 13.9 1.5 0.031 13.6 1.5 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF4190 PF13828.6 PVD23472.1 - 0.031 14.0 9.7 0.22 11.3 9.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) DUF3278 PF11683.8 PVD23472.1 - 0.088 12.9 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Tetraspanin PF00335.20 PVD23472.1 - 0.22 11.2 3.3 0.3 10.8 3.3 1.1 1 0 0 1 1 1 0 Tetraspanin family CD225 PF04505.12 PVD23473.1 - 8.5e-18 64.3 0.2 1.5e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein GIT_SHD PF08518.11 PVD23474.1 - 0.12 12.0 2.1 0.22 11.2 2.1 1.3 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT RGS PF00615.19 PVD23475.1 - 2.3e-31 108.5 0.2 3.4e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Arrestin_N PF00339.29 PVD23479.1 - 4.9e-35 120.7 0.0 1.2e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD23479.1 - 7.2e-16 58.9 0.0 2.5e-08 34.4 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD23479.1 - 3.5e-05 23.2 0.1 0.43 9.7 0.2 3.4 4 0 0 4 4 4 2 Rgp1 Vps26 PF03643.15 PVD23479.1 - 0.0055 15.7 0.0 0.021 13.8 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Spo0M PF07070.11 PVD23479.1 - 0.034 13.7 0.0 0.26 10.8 0.0 2.4 3 1 0 3 3 3 0 SpoOM protein MG2 PF01835.19 PVD23479.1 - 0.13 12.7 0.0 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 MG2 domain Gryzun PF07919.12 PVD23479.1 - 0.19 10.4 0.0 7.3 5.2 0.0 2.1 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi CD225 PF04505.12 PVD23480.1 - 1.5e-11 44.3 0.3 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 2 Interferon-induced transmembrane protein Mito_fiss_reg PF05308.11 PVD23480.1 - 0.0033 17.5 1.0 0.0033 17.5 1.0 2.4 2 1 0 2 2 2 1 Mitochondrial fission regulator Orbi_VP6 PF01516.16 PVD23480.1 - 0.04 13.4 0.1 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Cadherin_C_2 PF16492.5 PVD23480.1 - 0.052 14.3 0.0 9.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4235 PF14019.6 PVD23480.1 - 0.092 12.8 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) DUF3671 PF12420.8 PVD23480.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function T2SSF PF00482.23 PVD23480.1 - 0.12 12.3 0.1 1.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F SecE PF00584.20 PVD23480.1 - 2.6 8.0 4.1 0.51 10.3 0.6 1.6 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex CD225 PF04505.12 PVD23481.1 - 2.9e-19 69.0 0.5 4e-19 68.5 0.5 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 PVD23481.1 - 0.00014 21.5 3.8 0.0039 16.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4190) Voltage_CLC PF00654.20 PVD23481.1 - 0.0013 18.0 0.1 0.0014 17.9 0.1 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel DUF973 PF06157.11 PVD23481.1 - 0.0022 17.1 0.2 0.0023 17.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF3671 PF12420.8 PVD23481.1 - 0.0022 18.0 0.2 0.0026 17.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function PRIMA1 PF16101.5 PVD23481.1 - 0.0043 17.1 5.5 0.0043 17.1 5.5 2.3 1 1 1 2 2 1 1 Proline-rich membrane anchor 1 TauE PF01925.19 PVD23481.1 - 0.0045 16.6 0.1 0.0055 16.4 0.1 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Ninjurin PF04923.12 PVD23481.1 - 0.0063 16.4 0.2 0.0076 16.2 0.2 1.1 1 0 0 1 1 1 1 Ninjurin 7tm_3 PF00003.22 PVD23481.1 - 0.0091 15.7 0.1 0.0097 15.7 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Tetraspanin PF00335.20 PVD23481.1 - 0.012 15.3 2.0 0.016 14.9 2.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4234 PF14018.6 PVD23481.1 - 0.015 15.4 0.9 0.022 14.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4064 PF13273.6 PVD23481.1 - 0.022 15.0 2.7 0.04 14.2 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) COX2_TM PF02790.15 PVD23481.1 - 0.05 13.8 0.1 0.065 13.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF5453 PF17534.2 PVD23481.1 - 0.056 13.4 1.2 0.072 13.1 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) SdpI PF13630.6 PVD23481.1 - 0.062 13.4 0.3 0.12 12.5 0.3 1.4 1 1 0 1 1 1 0 SdpI/YhfL protein family TMPIT PF07851.13 PVD23481.1 - 0.078 12.2 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF5305 PF17231.2 PVD23481.1 - 0.11 11.9 1.0 0.83 9.0 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DHHC PF01529.20 PVD23481.1 - 0.13 12.4 1.3 0.16 12.1 1.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2830 PF11125.8 PVD23481.1 - 0.14 12.2 0.3 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) FixS PF03597.15 PVD23481.1 - 0.19 11.5 1.8 1.1 9.0 0.0 2.2 2 1 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type LapA_dom PF06305.11 PVD23481.1 - 7.1 6.5 7.4 5.3 6.9 0.1 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain CD225 PF04505.12 PVD23482.1 - 4e-19 68.5 0.4 6.1e-19 67.9 0.4 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4199 PF13858.6 PVD23482.1 - 0.077 13.4 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ninjurin PF04923.12 PVD23482.1 - 0.13 12.3 0.3 0.18 11.8 0.3 1.1 1 0 0 1 1 1 0 Ninjurin DUF4234 PF14018.6 PVD23482.1 - 0.15 12.2 1.4 0.38 10.9 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) SPW PF03779.14 PVD23482.1 - 1.6 8.3 5.5 0.52 9.9 0.9 2.1 2 0 0 2 2 2 0 SPW repeat Fasciclin PF02469.22 PVD23484.1 - 1.2e-111 368.2 0.1 1.5e-30 106.1 0.1 4.2 4 0 0 4 4 4 4 Fasciclin domain LRR_8 PF13855.6 PVD23485.1 - 6.9e-16 57.8 21.8 1e-07 31.6 4.3 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD23485.1 - 6.2e-15 55.1 23.2 4.2e-06 27.0 2.9 4.8 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD23485.1 - 2.3e-13 50.0 7.1 3.4e-08 33.2 0.6 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PVD23485.1 - 0.0072 16.7 16.3 4.8 8.1 0.8 6.7 6 0 0 6 6 6 2 Leucine Rich Repeat CCDC154 PF15450.6 PVD23485.1 - 0.012 14.2 0.8 0.019 13.6 0.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Prefoldin_2 PF01920.20 PVD23485.1 - 0.044 13.7 0.6 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 PVD23485.1 - 0.046 14.1 0.8 0.2 12.0 0.5 2.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Histone_H2A_C PF16211.5 PVD23486.1 - 2.4e-19 68.8 0.7 4.9e-19 67.8 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PVD23486.1 - 3.7e-15 56.4 0.0 5.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD23486.1 - 1.1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADK PF00406.22 PVD23487.1 - 1.4e-42 145.3 0.0 1.7e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PVD23487.1 - 1.8e-37 128.8 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD23487.1 - 7.6e-09 36.2 0.1 1.2e-08 35.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PVD23487.1 - 8.4e-07 28.5 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 PVD23487.1 - 3.8e-06 27.1 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PVD23487.1 - 0.1 12.3 0.3 9.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF2076 PF09849.9 PVD23488.1 - 0.18 11.8 5.6 0.067 13.2 2.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Med26 PF08711.11 PVD23489.1 - 6.8e-14 51.6 1.5 1.9e-13 50.2 1.5 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med26_C PF15693.5 PVD23489.1 - 3.8e-12 46.7 0.3 3.8e-12 46.7 0.3 2.6 2 0 0 2 2 2 1 Mediator complex subunit 26 C-terminal DUF3429 PF11911.8 PVD23490.1 - 5.2e-34 117.6 10.4 7.2e-34 117.1 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF4199 PF13858.6 PVD23490.1 - 0.024 15.0 1.4 0.024 15.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Yip1 PF04893.17 PVD23490.1 - 0.14 11.8 15.4 2.2 8.0 15.4 2.1 1 1 0 1 1 1 0 Yip1 domain DAGK_cat PF00781.24 PVD23491.1 - 1.9e-22 79.2 0.7 3.9e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain TFIIS_M PF07500.14 PVD23492.1 - 1.1e-09 38.7 0.0 3.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 PVD23492.1 - 3.4e-08 33.4 0.0 1.2e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Proteasome PF00227.26 PVD23493.1 - 2.2e-31 108.8 0.0 2.7e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ADSL_C PF10397.9 PVD23493.1 - 0.11 13.0 0.0 0.45 11.1 0.0 2.0 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus EB1 PF03271.17 PVD23494.1 - 4.6e-18 65.2 0.7 8.9e-18 64.3 0.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Fcf1 PF04900.12 PVD23496.1 - 7.9e-21 74.3 0.7 1.5e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Fcf1 JAB PF01398.21 PVD23497.1 - 2e-18 66.5 1.5 3.7e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_1 PF00515.28 PVD23498.1 - 1.1e-28 97.8 6.1 6.2e-11 41.6 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD23498.1 - 4.3e-19 67.0 11.0 3.5e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 PVD23498.1 - 4.6e-18 64.8 0.8 2.7e-16 59.1 0.1 2.4 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_11 PF13414.6 PVD23498.1 - 5.8e-17 61.1 7.1 1.7e-07 30.8 0.4 3.8 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 PVD23498.1 - 1.1e-16 59.5 4.6 5.7e-06 26.1 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD23498.1 - 8.9e-11 41.0 1.0 0.0051 16.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD23498.1 - 2.8e-10 39.8 8.7 7.8e-06 25.9 0.7 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD23498.1 - 4.3e-10 39.7 7.6 1.5e-06 28.4 2.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD23498.1 - 6.3e-09 36.3 0.2 1.7e-05 25.3 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD23498.1 - 2.2e-08 34.2 1.1 0.079 13.8 0.0 4.2 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 PVD23498.1 - 2e-05 23.9 1.2 0.01 15.1 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23498.1 - 4e-05 24.0 4.5 0.00051 20.5 0.1 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD23498.1 - 0.00054 20.1 0.5 0.039 14.1 0.2 3.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD23498.1 - 0.0022 18.0 7.4 0.67 10.1 0.1 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 PVD23498.1 - 0.0031 17.3 0.2 0.024 14.4 0.1 2.4 1 1 1 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 PVD23498.1 - 0.004 17.7 0.6 1.3 9.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TMP_2 PF06791.13 PVD23498.1 - 0.011 15.4 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein WAPL PF07814.13 PVD23498.1 - 0.013 14.3 0.7 0.028 13.2 0.2 1.8 1 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin SHNi-TPR PF10516.9 PVD23498.1 - 0.024 14.1 3.3 1.3 8.6 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR ApoLp-III PF07464.11 PVD23498.1 - 0.026 14.6 1.2 0.092 12.8 1.2 1.9 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_10 PF13374.6 PVD23498.1 - 0.36 10.8 13.5 0.18 11.7 0.5 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 PVD23498.1 - 0.53 10.4 5.6 10 6.3 0.0 3.9 2 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain GerD PF17898.1 PVD23498.1 - 7.5 6.6 7.7 1.3 9.0 2.6 2.4 3 1 0 3 3 2 0 Spore germination GerD central core domain RRM_1 PF00076.22 PVD23499.1 - 1.1e-21 76.5 0.0 2.8e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PVD23499.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 RL domain Metallophos PF00149.28 PVD23500.1 - 5.8e-35 121.6 6.3 2.3e-18 67.5 0.7 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PVD23500.1 - 1e-07 32.3 0.4 0.0016 18.6 0.1 3.9 2 2 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 PVD23500.1 - 0.089 11.8 0.0 28 3.6 0.1 3.2 3 0 0 3 3 3 0 PhoD-like phosphatase CLAMP PF14769.6 PVD23501.1 - 1.9e-05 25.0 5.8 3.1e-05 24.4 3.4 2.5 2 1 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 Lectin_C PF00059.21 PVD23502.1 - 1e-08 35.8 1.7 2.7e-08 34.5 1.7 1.7 1 0 0 1 1 1 1 Lectin C-type domain CLIP_SPH_mas PF18398.1 PVD23502.1 - 0.038 14.4 0.9 0.038 14.4 0.9 2.3 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade 7tm_1 PF00001.21 PVD23503.1 - 3e-53 180.8 12.9 4.8e-53 180.2 12.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23503.1 - 3e-07 30.1 10.1 0.00087 18.7 0.0 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD23503.1 - 0.001 18.5 11.0 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD23503.1 - 0.0016 18.1 9.6 0.0016 18.1 9.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23503.1 - 0.0022 17.8 11.7 0.018 14.8 10.1 2.4 2 1 0 2 2 2 1 Olfactory receptor Y_phosphatase PF00102.27 PVD23505.1 - 7.5e-58 195.9 0.0 2.6e-30 105.7 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase EphA2_TM PF14575.6 PVD23505.1 - 0.01 16.7 0.1 0.034 15.0 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3367 PF11847.8 PVD23505.1 - 0.072 11.0 1.1 0.11 10.3 1.1 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase TMEM154 PF15102.6 PVD23505.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 PVD23505.1 - 0.099 13.1 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Protocadherin PF08374.11 PVD23505.1 - 0.24 11.3 0.9 0.93 9.4 0.9 2.0 1 0 0 1 1 1 0 Protocadherin CcmD PF04995.14 PVD23505.1 - 1.3 9.2 3.9 4.1 7.6 3.9 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.20 PVD23505.1 - 1.6 8.7 4.5 3.8 7.5 4.5 1.5 1 0 0 1 1 1 0 Syndecan domain ShK PF01549.24 PVD23506.1 - 0.0004 20.9 10.0 0.00068 20.1 10.0 1.4 1 0 0 1 1 1 1 ShK domain-like Spt20 PF12090.8 PVD23506.1 - 8.5 5.9 15.7 14 5.2 15.7 1.4 1 0 0 1 1 1 0 Spt20 family CAP PF00188.26 PVD23507.1 - 2.5e-17 63.9 2.4 5.4e-17 62.8 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AIM5 PF17050.5 PVD23507.1 - 0.28 12.0 0.1 0.28 12.0 0.1 2.6 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 zf-C2H2 PF00096.26 PVD23510.1 - 7e-15 54.6 29.1 2.9e-05 24.3 5.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD23510.1 - 6.6e-12 45.3 11.7 5.8e-08 32.8 2.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD23510.1 - 9.2e-09 35.4 25.3 0.00091 19.9 3.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 PVD23510.1 - 0.0027 18.0 8.0 0.091 13.2 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 PVD23510.1 - 0.0035 17.9 8.9 0.16 12.6 0.4 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 PVD23510.1 - 0.011 16.0 6.3 0.022 15.1 6.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD23510.1 - 0.097 13.0 10.2 0.61 10.4 1.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 PVD23510.1 - 2 8.5 5.3 13 5.9 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 PVD23510.1 - 6.3 7.2 10.1 0.92 9.9 0.9 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 PVD23510.1 - 9.3 6.8 12.6 7.4 7.1 2.3 2.7 2 2 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Tubulin PF00091.25 PVD23511.1 - 1.6e-41 142.7 0.0 1.7e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD23511.1 - 3.8e-05 23.4 0.0 5.4e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Tubulin domain Neur_chan_LBD PF02931.23 PVD23512.1 - 5.6e-28 97.9 0.0 3.3e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD23512.1 - 0.017 15.2 1.9 0.017 15.2 1.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AKAP7_NLS PF10469.9 PVD23513.1 - 1.2e-34 120.0 0.2 2e-34 119.3 0.2 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Neur_chan_LBD PF02931.23 PVD23513.1 - 1.7e-17 63.6 0.1 2.9e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD23513.1 - 9.5e-14 52.0 10.1 9.5e-14 52.0 10.1 2.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region 2_5_RNA_ligase2 PF13563.6 PVD23513.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PVD23513.1 - 6.7e-05 23.0 0.0 0.11 12.7 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase DUF3827 PF12877.7 PVD23513.1 - 0.096 11.1 4.6 0.17 10.2 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PTE PF02126.18 PVD23514.1 - 5.8e-73 245.9 0.0 1.2e-72 244.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotriesterase family TRM13 PF05206.14 PVD23514.1 - 9.6e-55 185.9 0.1 1.6e-54 185.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 DUF5011 PF16403.5 PVD23514.1 - 0.11 12.6 0.8 16 5.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Complex1_LYR PF05347.15 PVD23515.1 - 0.0071 16.4 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DUF3808 PF10300.9 PVD23516.1 - 6.4e-143 476.9 4.7 8.3e-143 476.6 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 PVD23516.1 - 0.0001 22.5 0.1 0.22 11.9 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD23516.1 - 0.00021 21.2 2.6 1 9.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23516.1 - 0.0013 18.5 0.2 0.18 11.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD23516.1 - 0.0065 17.0 0.0 41 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD23516.1 - 0.021 15.0 0.0 17 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD23516.1 - 0.13 11.6 0.2 0.57 9.5 0.1 2.1 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 PVD23516.1 - 0.15 12.7 0.0 25 5.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UAA PF08449.11 PVD23517.1 - 4.6e-84 282.2 22.8 5.4e-84 281.9 22.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PVD23517.1 - 5.8e-05 23.3 31.0 0.0011 19.1 14.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family efThoc1 PF11957.8 PVD23518.1 - 1.3e-103 347.3 17.8 2e-91 307.1 11.9 2.5 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Death PF00531.22 PVD23518.1 - 1.9e-08 34.4 0.0 7.1e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Death domain DDE_Tnp_1_7 PF13843.6 PVD23519.1 - 5.5e-45 154.2 0.1 1.5e-44 152.7 0.0 1.7 2 0 0 2 2 2 1 Transposase IS4 Choline_transpo PF04515.12 PVD23520.1 - 1.5e-90 303.8 35.5 1.5e-90 303.8 35.5 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter MitoNEET_N PF10660.9 PVD23520.1 - 0.0098 15.9 0.1 0.064 13.3 0.1 2.4 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Gln-synt_C PF00120.24 PVD23521.1 - 3.6e-38 131.4 0.0 5.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Jiv90 PF14901.6 PVD23522.1 - 2.1e-38 130.3 7.8 2.1e-38 130.3 7.8 2.3 2 0 0 2 2 2 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 PVD23522.1 - 1.9e-19 69.6 0.1 3.8e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain OST3_OST6 PF04756.13 PVD23522.1 - 0.068 12.5 1.1 0.17 11.2 0.5 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF2722 PF10846.8 PVD23523.1 - 0.00014 20.9 13.2 0.00022 20.3 13.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PVD23523.1 - 0.00033 20.3 23.2 0.00053 19.7 23.2 1.3 1 0 0 1 1 1 1 Spt20 family EPL1 PF10513.9 PVD23523.1 - 0.065 13.6 5.2 0.1 13.0 5.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like MAP65_ASE1 PF03999.12 PVD23523.1 - 0.097 11.4 8.1 0.13 10.9 8.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RhlB PF12300.8 PVD23523.1 - 0.1 12.7 3.0 0.19 11.9 3.0 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB DUF4407 PF14362.6 PVD23523.1 - 0.23 10.8 2.9 0.35 10.2 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 PVD23523.1 - 0.42 10.5 34.8 0.82 9.6 34.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 PVD23523.1 - 0.51 8.2 16.6 0.67 7.8 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4770 PF15994.5 PVD23523.1 - 0.68 10.2 9.4 1.3 9.2 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 PVD23523.1 - 0.75 9.8 5.1 1.3 9.0 5.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 PVD23523.1 - 0.77 6.8 9.4 0.92 6.5 9.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer G0-G1_switch_2 PF15103.6 PVD23523.1 - 1 9.9 5.0 13 6.3 4.6 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 eIF-3_zeta PF05091.12 PVD23523.1 - 1.3 7.9 11.4 1.7 7.5 11.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 PVD23523.1 - 2 6.4 8.2 2.6 6.0 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TERB2 PF15101.6 PVD23523.1 - 2.2 8.3 10.3 3.5 7.6 10.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 PVD23523.1 - 3.2 5.9 17.7 4.7 5.4 17.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 PVD23523.1 - 3.9 6.2 12.1 5.6 5.6 12.1 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PVD23523.1 - 4 6.0 8.9 5.3 5.6 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_4 PF13637.6 PVD23525.1 - 2.2e-08 34.5 0.0 0.00044 20.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD23525.1 - 2e-06 28.0 0.3 0.0016 18.7 0.1 2.2 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD23525.1 - 2.5e-06 28.0 0.0 0.00058 20.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD23525.1 - 3.4e-06 27.3 0.0 0.023 15.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PVD23525.1 - 6.2e-05 23.1 0.0 1.1 10.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat T6SS-SciN PF12790.7 PVD23525.1 - 0.13 12.0 0.0 1.1 9.0 0.0 1.9 1 1 1 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 DUF2102 PF09875.9 PVD23526.1 - 0.23 11.2 2.2 0.48 10.2 2.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) TPT PF03151.16 PVD23527.1 - 8e-22 77.9 3.5 1e-21 77.5 3.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family LicD PF04991.13 PVD23528.1 - 7.2e-07 29.6 0.5 2e-06 28.2 0.2 1.9 2 1 0 2 2 2 1 LicD family DUF987 PF06174.11 PVD23528.1 - 0.15 12.0 0.1 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF987) Elongin_A PF06881.11 PVD23529.1 - 0.014 15.9 0.2 0.086 13.4 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Fer4_13 PF13370.6 PVD23529.1 - 0.061 13.9 0.7 0.15 12.6 0.1 2.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Jun PF03957.13 PVD23530.1 - 3.5e-37 128.5 7.1 5.3e-37 127.9 7.1 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 PVD23530.1 - 5.4e-17 61.7 12.6 5.4e-17 61.7 12.6 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PVD23530.1 - 6.5e-08 32.5 12.5 1.6e-07 31.3 12.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD23530.1 - 1.4e-07 31.9 8.1 2.9e-07 30.9 8.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 PVD23530.1 - 0.036 14.5 1.8 0.098 13.1 1.8 1.7 1 0 0 1 1 1 0 Cell division protein ZapB DUF2383 PF09537.10 PVD23530.1 - 0.078 13.3 0.3 0.15 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) MutS_V PF00488.21 PVD23531.1 - 5.7e-50 170.0 0.0 1.1e-49 169.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MFS_1 PF07690.16 PVD23531.1 - 2.4e-35 122.1 50.7 5.1e-31 107.9 32.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 PVD23531.1 - 4e-11 42.4 21.5 3.8e-10 39.2 21.2 2.3 1 1 0 1 1 1 1 MFS_1 like family MutS_III PF05192.18 PVD23531.1 - 3.6e-10 40.4 1.3 1.5e-09 38.4 0.4 2.2 2 0 0 2 2 2 1 MutS domain III MFS_2 PF13347.6 PVD23531.1 - 1.2e-05 24.1 23.8 1.2e-05 24.1 23.8 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein Steroid_dh PF02544.16 PVD23531.1 - 0.033 14.2 1.3 4.1 7.4 0.5 2.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase AAA_14 PF13173.6 PVD23531.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FERM_N PF09379.10 PVD23533.1 - 9.7e-19 67.1 0.4 4e-18 65.1 0.2 2.1 2 0 0 2 2 2 1 FERM N-terminal domain 4_1_CTD PF05902.13 PVD23533.1 - 3.7e-17 62.4 0.1 7.3e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) FERM_M PF00373.18 PVD23533.1 - 2.2e-14 53.9 0.0 4.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 PVD23533.1 - 4.8e-13 49.3 0.1 9.5e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain AP_endonuc_2 PF01261.24 PVD23534.1 - 7.5e-25 87.6 0.0 1.2e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FAD_binding_4 PF01565.23 PVD23534.1 - 5.6e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ras PF00071.22 PVD23536.1 - 1.2e-62 210.3 1.5 1.5e-62 210.0 1.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD23536.1 - 2.1e-33 115.1 0.8 3.6e-33 114.3 0.8 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD23536.1 - 1.4e-14 54.0 0.2 1.9e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD23536.1 - 5.9e-05 22.6 0.2 0.00033 20.1 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PVD23536.1 - 0.00027 20.4 0.2 0.00037 19.9 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD23536.1 - 0.00031 20.8 0.1 0.00079 19.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD23536.1 - 0.00041 19.9 0.1 0.0013 18.3 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD23536.1 - 0.00064 19.7 0.2 0.09 12.7 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 PVD23536.1 - 0.0013 18.3 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B G-alpha PF00503.20 PVD23536.1 - 0.0022 17.2 1.2 2.8 7.0 0.0 3.0 1 1 1 2 2 2 2 G-protein alpha subunit DUF2757 PF10955.8 PVD23536.1 - 0.036 14.3 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) muHD PF10291.9 PVD23537.1 - 2.5e-50 171.4 0.0 4.9e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Reeler PF02014.16 PVD23537.1 - 3.2e-32 112.0 0.9 3.2e-32 112.0 0.9 2.0 2 0 0 2 2 2 1 Reeler domain FCH PF00611.23 PVD23537.1 - 2.7e-12 46.8 0.5 1.5e-11 44.4 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Reeler PF02014.16 PVD23538.1 - 1.3e-23 84.2 0.9 2.1e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Reeler domain Syndecan PF01034.20 PVD23540.1 - 0.29 11.1 0.4 0.44 10.5 0.4 1.2 1 0 0 1 1 1 0 Syndecan domain Laminin_EGF PF00053.24 PVD23543.1 - 0.1 12.8 105.2 1.6 9.0 17.3 8.1 1 1 6 7 7 7 0 Laminin EGF domain TPR_12 PF13424.6 PVD23545.1 - 5e-11 42.7 1.6 7.4e-07 29.4 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat NACHT PF05729.12 PVD23545.1 - 2e-07 31.1 0.0 7.1e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 PVD23545.1 - 3.3e-06 26.8 0.2 0.021 14.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 PVD23545.1 - 0.00022 21.6 0.0 0.0057 17.1 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 PVD23545.1 - 0.00095 19.8 0.0 23 6.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD23545.1 - 0.0027 17.6 2.0 0.066 13.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23545.1 - 0.014 15.2 0.7 0.014 15.2 0.7 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat UvrD_C PF13361.6 PVD23545.1 - 0.024 14.0 3.1 1 8.7 0.1 3.0 2 2 0 2 2 2 0 UvrD-like helicase C-terminal domain DAP3 PF10236.9 PVD23545.1 - 0.028 13.6 0.0 0.094 11.9 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 PVD23545.1 - 0.049 12.8 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain TPR_2 PF07719.17 PVD23545.1 - 0.062 13.4 5.7 0.23 11.7 0.3 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat CpXC PF14353.6 PVD23545.1 - 0.099 12.7 0.2 0.54 10.3 0.1 2.3 2 0 0 2 2 2 0 CpXC protein AAA PF00004.29 PVD23545.1 - 0.16 12.4 0.1 1.3 9.5 0.1 2.5 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_8 PF13181.6 PVD23545.1 - 0.23 11.8 8.3 0.19 12.0 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SEA PF01390.20 PVD23546.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 SEA domain Rax2 PF12768.7 PVD23546.1 - 0.0066 15.9 0.1 0.0097 15.4 0.1 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DOMON PF03351.17 PVD23546.1 - 0.023 14.9 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 DOMON domain DUF973 PF06157.11 PVD23546.1 - 0.038 13.1 0.2 0.052 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Shisa PF13908.6 PVD23546.1 - 0.053 13.8 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DOMON PF03351.17 PVD23547.1 - 5.7e-29 100.9 3.6 1e-13 51.6 0.0 3.4 3 0 0 3 3 3 3 DOMON domain LPMO_10 PF03067.15 PVD23547.1 - 1.4e-05 25.8 0.0 5.6e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading EGF_2 PF07974.13 PVD23547.1 - 1.1 9.7 10.3 0.45 10.9 3.2 2.6 2 0 0 2 2 2 0 EGF-like domain EGF_alliinase PF04863.13 PVD23547.1 - 1.4 9.4 5.0 9.2 6.8 5.0 2.4 1 1 0 1 1 1 0 Alliinase EGF-like domain TOH_N PF12549.8 PVD23547.1 - 4.2 7.3 8.2 44 4.1 0.0 4.5 5 0 0 5 5 5 0 Tyrosine hydroxylase N terminal ELO PF01151.18 PVD23548.1 - 8.9e-66 222.0 19.5 1.1e-65 221.7 19.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4905 PF16248.5 PVD23548.1 - 0.48 10.4 3.8 0.34 10.8 0.2 2.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4905) NDUF_B7 PF05676.13 PVD23549.1 - 2e-22 78.6 5.4 2.8e-22 78.2 5.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) AAA_18 PF13238.6 PVD23549.1 - 0.12 13.0 0.8 0.14 12.7 0.8 1.2 1 0 0 1 1 1 0 AAA domain Ebp2 PF05890.12 PVD23550.1 - 1.2e-76 257.8 23.9 1.6e-76 257.4 23.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PTPlike_phytase PF14566.6 PVD23550.1 - 0.16 12.1 4.8 0.64 10.1 4.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate ECH_1 PF00378.20 PVD23551.1 - 7.1e-33 114.0 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase WD40 PF00400.32 PVD23551.1 - 7.2e-25 86.8 13.9 0.00038 21.2 0.2 7.0 5 1 1 6 6 6 5 WD domain, G-beta repeat ECH_2 PF16113.5 PVD23551.1 - 4.7e-19 69.1 0.5 7.6e-19 68.4 0.5 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ANAPC4_WD40 PF12894.7 PVD23551.1 - 7.9e-14 51.7 2.6 9.7e-05 22.6 0.4 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD23551.1 - 2.2e-07 30.9 0.1 0.22 11.4 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD23551.1 - 0.00086 18.4 0.0 0.21 10.5 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PVD23551.1 - 0.25 9.9 5.8 0.22 10.1 0.1 2.9 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Peptidase_C1 PF00112.23 PVD23552.1 - 3.4e-54 184.2 0.6 4.6e-54 183.8 0.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Somatomedin_B PF01033.17 PVD23552.1 - 0.0029 18.0 13.8 0.01 16.2 13.8 2.0 1 1 0 1 1 1 1 Somatomedin B domain Peptidase_C1_2 PF03051.15 PVD23552.1 - 0.087 11.6 0.0 0.3 9.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase C1-like family TERB2 PF15101.6 PVD23552.1 - 0.22 11.5 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ank_2 PF12796.7 PVD23553.1 - 3.3e-18 66.0 0.1 6.5e-12 45.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD23553.1 - 7.4e-14 51.9 0.0 5.9e-10 39.5 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23553.1 - 4.7e-13 48.0 0.1 1.1e-05 25.4 0.0 3.6 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 PVD23553.1 - 6.1e-11 42.3 0.0 1.4e-05 25.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD23553.1 - 7.2e-10 38.9 0.1 9.4e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_9 PF12781.7 PVD23553.1 - 7.9e-06 25.2 0.0 7.9e-06 25.2 0.0 3.1 3 1 0 3 3 2 1 ATP-binding dynein motor region HTH_16 PF12645.7 PVD23553.1 - 0.035 14.2 1.2 4.6 7.4 0.6 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain IQ PF00612.27 PVD23553.1 - 0.046 13.5 1.0 0.11 12.4 1.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif TrbI_Ftype PF09677.10 PVD23553.1 - 0.27 11.6 1.8 0.76 10.1 1.8 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) AAA_23 PF13476.6 PVD23553.1 - 0.57 10.6 24.6 0.02 15.4 3.7 3.0 3 0 0 3 3 3 0 AAA domain DUF262 PF03235.14 PVD23553.1 - 0.96 9.6 10.5 1.9 8.6 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF262 Imm49 PF15575.6 PVD23553.1 - 1.6 8.5 8.0 4.4 7.0 1.8 2.4 2 0 0 2 2 2 0 Immunity protein 49 DUF3492 PF11997.8 PVD23553.1 - 5 6.8 7.6 9.3 5.9 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) MIF4G_like_2 PF09090.11 PVD23553.1 - 6.2 6.2 20.1 0.85 9.0 8.6 2.4 2 0 0 2 2 2 0 MIF4G like DDHD PF02862.17 PVD23553.1 - 8.3 6.5 7.7 8.7 6.4 1.9 2.2 2 0 0 2 2 2 0 DDHD domain DMA PF03474.14 PVD23554.1 - 3e-16 58.7 0.0 6.6e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif DM PF00751.18 PVD23555.1 - 2.4e-22 78.6 12.5 3.4e-22 78.1 12.5 1.2 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 PVD23557.1 - 4.9e-10 38.8 0.1 8.5e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 DMRTA motif DM PF00751.18 PVD23558.1 - 1.6e-23 82.3 10.7 2.6e-23 81.7 10.7 1.3 1 0 0 1 1 1 1 DM DNA binding domain Anp1 PF03452.14 PVD23558.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Anp1 DUF5625 PF18539.1 PVD23559.1 - 0.062 13.6 0.0 0.087 13.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5625) SLX9 PF15341.6 PVD23561.1 - 0.0041 17.5 4.2 0.0041 17.5 4.2 7.1 6 3 1 7 7 7 1 Ribosome biogenesis protein SLX9 TTL PF03133.15 PVD23562.1 - 3.4e-47 161.0 0.9 5.1e-47 160.4 0.9 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Dala_Dala_lig_C PF07478.13 PVD23562.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 PVD23562.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp PsiB PF06290.11 PVD23564.1 - 0.044 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) DUF4869 PF16163.5 PVD23564.1 - 0.048 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) C6 PF01681.17 PVD23564.1 - 0.18 12.4 3.1 0.58 10.7 1.1 2.4 1 1 1 2 2 2 0 C6 domain Lectin_C PF00059.21 PVD23565.1 - 5.4e-15 56.0 0.4 5.4e-15 56.0 0.4 2.2 2 0 0 2 2 2 1 Lectin C-type domain Lectin_C PF00059.21 PVD23567.1 - 5.6e-14 52.8 2.3 1.1e-10 42.2 0.0 3.0 3 0 0 3 3 3 2 Lectin C-type domain Lectin_C PF00059.21 PVD23569.1 - 9.8e-15 55.2 0.7 2.4e-14 54.0 0.7 1.6 1 0 0 1 1 1 1 Lectin C-type domain AA_kinase PF00696.28 PVD23569.1 - 0.15 11.6 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Amino acid kinase family DUF4381 PF14316.6 PVD23570.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ABC_membrane_2 PF06472.15 PVD23572.1 - 2.9e-97 325.3 7.8 3.9e-97 324.9 7.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PVD23572.1 - 1.3e-17 64.6 0.0 2.9e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD23572.1 - 0.00077 19.0 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PVD23572.1 - 0.0031 18.1 0.1 0.0084 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PVD23572.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD23572.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 PVD23572.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 PVD23572.1 - 0.13 12.3 0.0 0.69 9.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PVD23572.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PVD23572.1 - 0.18 11.1 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sas10 PF09368.10 PVD23573.1 - 3.1e-24 85.3 10.6 3.1e-24 85.3 10.6 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 PVD23573.1 - 1.7e-05 25.3 0.9 9e-05 23.0 0.1 2.8 2 1 0 2 2 2 1 Sas10/Utp3/C1D family 7tm_1 PF00001.21 PVD23574.1 - 1.8e-57 194.7 15.1 2.7e-57 194.1 15.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD23574.1 - 0.00045 20.0 8.9 0.00045 20.0 8.9 2.3 2 0 0 2 2 2 1 Olfactory receptor TF_AP-2 PF03299.14 PVD23576.1 - 7.1e-75 251.3 0.1 7.7e-74 247.9 0.1 2.0 1 1 0 1 1 1 1 Transcription factor AP-2 Sec-ASP3 PF15432.6 PVD23577.1 - 0.1 12.8 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 PARP PF00644.20 PVD23579.1 - 1.6e-08 34.4 1.8 1.3e-07 31.4 0.1 3.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Acetyltransf_10 PF13673.7 PVD23579.1 - 6.8e-06 26.0 0.2 1.6e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD23579.1 - 0.0002 21.6 0.2 0.00054 20.2 0.2 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CDC45 PF02724.14 PVD23579.1 - 0.0021 16.4 14.1 0.004 15.5 14.1 1.4 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 PVD23579.1 - 0.052 12.1 39.2 0.1 11.2 39.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 PVD23579.1 - 0.2 11.1 38.5 0.017 14.5 33.9 1.5 2 0 0 2 2 2 0 SDA1 Drc1-Sld2 PF11719.8 PVD23579.1 - 2.2 7.8 18.5 4.5 6.7 18.5 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein zf-H2C2_2 PF13465.6 PVD23580.1 - 5.4e-13 48.7 10.4 1.5e-07 31.6 3.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD23580.1 - 5.7e-13 48.6 24.0 3.1e-05 24.2 3.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD23580.1 - 2.4e-08 34.1 20.7 0.00058 20.5 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PVD23580.1 - 0.0022 17.9 5.9 0.012 15.5 1.0 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 PVD23580.1 - 0.042 13.7 0.2 0.15 11.9 0.2 2.0 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 PVD23580.1 - 0.24 11.8 4.1 6.1 7.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD23580.1 - 1.7 9.0 9.2 6.8 7.1 2.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD23580.1 - 2.7 8.3 8.0 1.3 9.4 0.6 2.8 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PNP_UDP_1 PF01048.20 PVD23581.1 - 1.9e-45 155.0 0.0 2.2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Semialdhyde_dh PF01118.24 PVD23581.1 - 0.13 12.7 0.1 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Hist_deacetyl PF00850.19 PVD23582.1 - 1.8e-74 251.0 0.1 2.5e-74 250.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF5491 PF17595.2 PVD23582.1 - 0.14 12.5 0.2 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5491) CH_2 PF06294.11 PVD23583.1 - 7.5e-21 74.1 0.3 2.2e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 CH-like domain in sperm protein ADK PF00406.22 PVD23583.1 - 1e-08 35.4 1.8 1.4e-05 25.3 0.0 4.0 4 0 0 4 4 4 2 Adenylate kinase AAA_17 PF13207.6 PVD23583.1 - 0.0066 16.9 9.4 1.9 8.9 0.0 4.8 4 1 0 4 4 4 2 AAA domain Peptidase_A22B PF04258.13 PVD23584.1 - 5.5e-95 318.1 6.9 8.3e-95 317.6 6.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase EF-hand_4 PF12763.7 PVD23584.1 - 1.2e-29 102.3 0.0 2.2e-22 79.0 0.0 3.6 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD23584.1 - 7e-09 34.6 0.3 0.0014 18.0 0.1 3.1 3 0 0 3 3 2 2 EF hand EF-hand_5 PF13202.6 PVD23584.1 - 3.3e-07 29.5 1.1 0.0037 16.7 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD23584.1 - 1.1e-06 29.0 0.9 0.026 14.9 0.0 3.7 4 0 0 4 4 3 2 EF-hand domain pair ERM PF00769.19 PVD23584.1 - 1.3e-06 28.4 25.3 2.1e-06 27.7 25.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family EF-hand_6 PF13405.6 PVD23584.1 - 2.7e-06 26.9 3.5 0.0079 16.1 0.0 3.3 3 0 0 3 3 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD23584.1 - 0.0001 22.1 0.1 0.33 10.8 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair SPP PF06550.11 PVD23584.1 - 0.0003 20.4 6.3 0.0003 20.4 6.3 1.7 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Spc7 PF08317.11 PVD23584.1 - 0.0012 17.8 36.4 0.0012 17.8 36.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein BCD PF15461.6 PVD23584.1 - 0.002 17.7 1.6 0.0031 17.1 0.8 1.7 2 0 0 2 2 1 1 Beta-carotene 15,15'-dioxygenase DUF2968 PF11180.8 PVD23584.1 - 0.008 15.8 45.9 0.01 15.5 25.6 2.5 2 1 1 3 3 2 2 Protein of unknown function (DUF2968) DUF3450 PF11932.8 PVD23584.1 - 0.014 14.7 37.8 0.0077 15.6 17.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TRAF_BIRC3_bd PF16673.5 PVD23584.1 - 0.024 14.4 0.8 0.024 14.4 0.8 3.6 3 1 0 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain YscO PF07321.12 PVD23584.1 - 0.054 13.4 32.7 1.7 8.6 16.9 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO MAP65_ASE1 PF03999.12 PVD23584.1 - 0.064 12.0 23.2 0.11 11.1 23.2 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4164 PF13747.6 PVD23584.1 - 0.065 13.5 27.9 0.11 12.8 9.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) FPP PF05911.11 PVD23584.1 - 0.073 11.3 31.8 0.13 10.5 31.8 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 PVD23584.1 - 0.084 13.4 47.1 0.42 11.1 34.2 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 PVD23584.1 - 0.09 13.1 38.0 0.26 11.7 19.8 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_13 PF13166.6 PVD23584.1 - 0.13 10.9 29.1 1.3 7.6 29.1 1.9 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 PVD23584.1 - 0.14 12.1 45.9 0.094 12.7 36.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 PVD23584.1 - 0.17 11.3 34.3 0.34 10.3 34.3 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal IFT57 PF10498.9 PVD23584.1 - 0.51 9.3 36.0 0.16 10.9 11.3 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 RasGAP_C PF03836.15 PVD23584.1 - 1.1 9.4 30.7 3.1 7.9 20.2 2.9 2 1 1 3 3 2 0 RasGAP C-terminus BicD PF09730.9 PVD23584.1 - 1.3 7.4 30.5 1.8 6.9 30.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Fez1 PF06818.15 PVD23584.1 - 1.3 9.4 35.1 1.1 9.6 32.5 1.9 1 1 0 1 1 1 0 Fez1 CALCOCO1 PF07888.11 PVD23584.1 - 2 7.2 38.4 2.8 6.7 38.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 PVD23584.1 - 2.4 7.4 27.3 6.6 6.0 27.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.19 PVD23584.1 - 2.8 5.6 44.2 5.8 4.6 44.2 1.4 1 1 0 1 1 1 0 Myosin tail HlyD_D23 PF16576.5 PVD23584.1 - 2.8 7.1 11.7 1.4 8.1 9.4 1.6 2 0 0 2 2 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Cluap1 PF10234.9 PVD23584.1 - 3.7 6.9 31.6 8.2 5.7 31.6 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF3584 PF12128.8 PVD23584.1 - 6.4 4.1 31.5 10 3.5 31.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4239 PF14023.6 PVD23584.1 - 6.5 6.4 8.2 15 5.2 8.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF1664 PF07889.12 PVD23584.1 - 6.6 6.8 27.2 0.33 11.0 11.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ADIP PF11559.8 PVD23584.1 - 7.4 6.6 46.4 1.4 8.9 12.4 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 PVD23584.1 - 8.3 4.6 37.8 14 3.9 37.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Presenilin PF01080.17 PVD23584.1 - 8.5 5.0 22.1 0.028 13.2 1.7 2.4 2 0 0 2 2 2 0 Presenilin PI3K_P85_iSH2 PF16454.5 PVD23584.1 - 8.5 5.9 34.9 16 5.1 20.0 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lipase PF00151.19 PVD23585.1 - 6e-95 318.4 0.0 7.8e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 PVD23585.1 - 2.3e-08 34.9 0.8 3.6e-08 34.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD23585.1 - 0.047 13.0 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 PVD23585.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Y_phosphatase PF00102.27 PVD23586.1 - 1.7e-141 469.7 0.6 1e-75 254.3 0.5 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 PVD23586.1 - 1.4e-09 37.8 0.8 0.00063 19.6 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD23586.1 - 0.00011 22.2 0.0 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family RIFIN PF02009.16 PVD23586.1 - 0.0011 19.0 0.8 0.0011 19.0 0.8 1.6 2 0 0 2 2 2 1 Rifin Yeast_MT PF11403.8 PVD23586.1 - 0.0046 17.5 10.9 0.0046 17.5 10.9 7.1 5 1 1 6 6 6 2 Yeast metallothionein SKG6 PF08693.10 PVD23586.1 - 0.048 13.1 5.6 0.092 12.2 5.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTPlike_phytase PF14566.6 PVD23586.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 PVD23586.1 - 0.099 12.2 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family EphA2_TM PF14575.6 PVD23586.1 - 0.15 13.0 0.0 0.37 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DEFB136 PF17333.2 PVD23586.1 - 3.8 7.5 48.7 0.48 10.4 1.2 6.4 6 1 0 6 6 6 0 Beta defensin 136 DEP PF00610.21 PVD23587.1 - 2.9e-15 56.1 0.0 5.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 PVD23587.1 - 5.7e-05 23.0 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain Stig1 PF04885.13 PVD23587.1 - 0.072 13.6 1.9 0.26 11.8 1.9 2.0 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Oxysterol_BP PF01237.18 PVD23588.1 - 3.6e-82 276.2 3.5 3.6e-80 269.6 3.5 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 PVD23588.1 - 5.2e-16 59.1 1.9 1.2e-15 57.9 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 PVD23588.1 - 9.9e-10 38.6 0.3 2.2e-09 37.4 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PVD23588.1 - 3.2e-06 27.5 9.6 7.4e-06 26.3 2.8 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 PVD23588.1 - 0.00043 20.5 0.1 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PVD23588.1 - 0.031 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 PH domain Sec3-PIP2_bind PF15277.6 PVD23588.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_9 PF15410.6 PVD23588.1 - 0.14 12.5 0.8 0.67 10.3 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain AAA PF00004.29 PVD23589.1 - 1.2e-32 113.1 0.0 1e-27 97.1 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 PVD23589.1 - 5e-19 68.2 0.2 1.7e-18 66.5 0.2 1.9 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 PVD23589.1 - 4.5e-09 36.0 0.0 1.5e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 PVD23589.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RRM_1 PF00076.22 PVD23589.1 - 0.12 12.2 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thiolase_N PF00108.23 PVD23590.1 - 6.4e-78 261.7 0.1 9.9e-78 261.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD23590.1 - 2.6e-45 153.1 0.0 1.3e-44 150.8 0.0 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PVD23590.1 - 4.4e-07 29.7 0.3 1.1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 PVD23590.1 - 0.01 14.6 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) 3HCDH_N PF02737.18 PVD23591.1 - 1.4e-58 197.7 0.6 3.4e-58 196.5 0.6 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 PVD23591.1 - 1.5e-38 132.5 0.0 3.2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 PVD23591.1 - 6.8e-34 116.4 0.0 8.5e-27 93.6 0.1 3.4 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 PVD23591.1 - 2.2e-26 93.2 0.0 4.4e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 PVD23591.1 - 0.086 13.0 0.1 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PVD23591.1 - 0.17 12.5 0.6 0.57 10.8 0.1 2.3 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NDK PF00334.19 PVD23593.1 - 6.9e-38 129.7 0.1 8.9e-38 129.4 0.1 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 7tm_1 PF00001.21 PVD23595.1 - 6.8e-38 130.5 3.2 8.9e-38 130.1 3.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23595.1 - 0.0012 18.6 13.1 0.0019 17.9 13.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23595.1 - 0.024 14.4 11.8 0.11 12.2 11.8 1.8 1 1 0 1 1 1 0 Olfactory receptor DUF4293 PF14126.6 PVD23595.1 - 4 7.7 11.0 0.24 11.6 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) 7tm_1 PF00001.21 PVD23597.1 - 2e-05 24.0 2.7 2.8e-05 23.6 2.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4472 PF14739.6 PVD23598.1 - 6.5e-31 107.2 17.2 6.5e-31 107.2 17.2 5.5 4 1 1 5 5 5 1 Domain of unknown function (DUF4472) Kinesin PF00225.23 PVD23598.1 - 2.9e-27 95.5 0.0 6.5e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD23598.1 - 7.7e-16 58.4 0.0 7.7e-16 58.4 0.0 3.0 4 0 0 4 4 4 1 Microtubule binding DUF724 PF05266.14 PVD23598.1 - 0.013 15.3 3.4 0.013 15.3 3.4 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF724) FUSC PF04632.12 PVD23598.1 - 0.08 11.5 9.5 0.063 11.8 3.5 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Scaffolding_pro PF11418.8 PVD23598.1 - 0.26 11.9 0.1 0.26 11.9 0.1 4.9 4 1 0 5 5 5 0 Phi29 scaffolding protein WD40 PF00400.32 PVD23599.1 - 3.1e-21 75.3 7.4 0.0017 19.1 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23599.1 - 7.8e-10 38.9 0.0 0.055 13.8 0.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD23599.1 - 0.00048 19.2 0.1 0.076 12.0 0.1 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD23599.1 - 0.00072 19.5 0.0 0.46 10.3 0.0 3.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apt1 PF10351.9 PVD23599.1 - 2.6 6.8 8.0 3.7 6.3 8.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 PVD23599.1 - 6.3 6.4 13.3 13 5.4 13.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM60A PF15396.6 PVD23599.1 - 9.2 6.2 8.8 24 4.8 8.8 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Rubella_E2 PF05749.11 PVD23600.1 - 0.0011 18.5 0.4 0.0011 18.5 0.4 1.9 2 0 0 2 2 2 1 Rubella membrane glycoprotein E2 Pkinase PF00069.25 PVD23603.1 - 1.6e-43 149.0 0.0 2.1e-26 92.9 0.0 4.9 4 2 1 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23603.1 - 3.6e-21 75.6 2.8 5.2e-10 39.0 0.0 3.7 2 1 1 3 3 3 2 Protein tyrosine kinase Rho_Binding PF08912.11 PVD23603.1 - 4.6e-15 56.2 16.8 4.6e-15 56.2 16.8 12.4 6 5 7 13 13 13 1 Rho Binding PH PF00169.29 PVD23603.1 - 1.2e-05 25.8 0.1 0.0026 18.2 0.0 3.0 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 PVD23603.1 - 0.00014 21.7 5.0 0.00026 20.8 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 PVD23603.1 - 0.0016 19.1 1.6 0.0049 17.5 1.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Cytochrome_C7 PF14522.6 PVD23603.1 - 0.065 13.2 2.5 0.54 10.3 2.5 2.7 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c RPA_C PF08784.11 PVD23604.1 - 7.8e-17 61.8 0.6 3.3e-16 59.8 0.2 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 PVD23604.1 - 3.7e-06 26.8 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 PVD23604.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 STN1_2 PF09170.10 PVD23604.1 - 0.015 15.5 0.1 2.1 8.5 0.0 2.4 1 1 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 TRAM_LAG1_CLN8 PF03798.16 PVD23605.1 - 7.1e-26 91.2 12.8 7.1e-26 91.2 12.8 1.3 2 0 0 2 2 2 1 TLC domain RabGAP-TBC PF00566.18 PVD23606.1 - 9.5e-56 188.8 0.4 9.5e-56 188.8 0.4 3.3 4 0 0 4 4 4 1 Rab-GTPase-TBC domain PH PF00169.29 PVD23606.1 - 4.7e-09 36.7 0.4 1.8e-08 34.8 0.4 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PVD23606.1 - 8.5e-06 26.0 0.1 4.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DUF4874 PF16173.5 PVD23607.1 - 0.06 13.0 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Myosin_tail_1 PF01576.19 PVD23608.1 - 1.5e-19 69.5 18.5 5.4e-16 57.7 9.3 2.0 1 1 1 2 2 2 2 Myosin tail TelA PF05816.11 PVD23608.1 - 0.0012 17.9 9.9 0.0015 17.6 9.9 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) COG2 PF06148.11 PVD23608.1 - 0.018 15.2 6.3 0.026 14.6 6.3 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.10 PVD23608.1 - 0.021 15.0 12.9 0.043 14.0 12.9 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.12 PVD23608.1 - 0.63 10.1 17.4 1.2 9.2 17.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 PVD23608.1 - 1.4 8.5 8.4 1 8.9 1.3 2.1 1 1 1 2 2 2 0 fzo-like conserved region APG6_N PF17675.1 PVD23608.1 - 3.1 8.4 16.1 5.3 7.6 16.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DASH_Dad3 PF08656.10 PVD23608.1 - 8.5 6.5 8.1 35 4.6 6.4 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad3 ERG4_ERG24 PF01222.17 PVD23610.1 - 4.9e-68 229.9 19.9 5.7e-68 229.6 19.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Neur_chan_LBD PF02931.23 PVD23611.1 - 1.8e-36 125.6 0.0 2.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD23611.1 - 2.5e-10 40.8 7.6 1.2e-07 32.0 1.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region EIF_2_alpha PF07541.12 PVD23612.1 - 8e-37 125.9 0.6 1.7e-36 124.8 0.6 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit Methyltransf_25 PF13649.6 PVD23612.1 - 6e-08 33.3 0.1 5.8e-07 30.1 0.0 2.8 4 0 0 4 4 3 1 Methyltransferase domain CARM1 PF11531.8 PVD23612.1 - 6.4e-08 32.8 0.1 1.5e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal Methyltransf_9 PF08003.11 PVD23612.1 - 3.2e-07 29.6 0.0 6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 PVD23612.1 - 1.8e-06 27.6 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD23612.1 - 3.2e-06 26.8 0.0 9.3e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain S1 PF00575.23 PVD23612.1 - 4.3e-06 27.0 0.7 9e-06 25.9 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Methyltransf_11 PF08241.12 PVD23612.1 - 1.7e-05 25.3 0.0 0.00018 22.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain PRMT5 PF05185.16 PVD23612.1 - 0.00023 21.1 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 PVD23612.1 - 0.0006 19.8 0.1 0.0095 15.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 PVD23612.1 - 0.0027 17.6 0.1 0.0051 16.7 0.1 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_23 PF13489.6 PVD23612.1 - 0.0035 17.2 0.0 0.027 14.3 0.0 2.5 1 1 1 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PVD23612.1 - 0.0036 17.0 0.0 0.0095 15.6 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PVD23612.1 - 0.015 16.0 0.0 0.14 12.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 PVD23612.1 - 0.017 14.5 0.1 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 PVD23612.1 - 0.021 14.6 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 PVD23612.1 - 0.088 11.9 0.0 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase Med8 PF10232.9 PVD23613.1 - 1.6e-56 191.5 2.7 1.9e-56 191.2 2.7 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Neuro_bHLH PF12533.8 PVD23613.1 - 0.26 12.5 6.8 0.19 12.9 5.0 1.7 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Ribosomal_L22 PF00237.19 PVD23613.1 - 0.45 10.8 2.4 1.5 9.1 2.0 1.8 1 1 1 2 2 2 0 Ribosomal protein L22p/L17e CBFD_NFYB_HMF PF00808.23 PVD23614.1 - 3.9e-22 78.3 1.3 2.8e-21 75.5 1.2 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PVD23614.1 - 3e-15 56.7 0.3 3e-15 56.7 0.3 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 PVD23614.1 - 0.056 13.8 0.1 0.056 13.8 0.1 2.1 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Pkinase PF00069.25 PVD23615.1 - 3.5e-48 164.3 0.0 5.7e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23615.1 - 1.2e-30 106.6 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.9 PVD23615.1 - 2.1e-21 76.1 0.1 4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Kinase-like PF14531.6 PVD23615.1 - 1.8e-05 24.2 0.0 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PVD23615.1 - 0.00016 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DSPc PF00782.20 PVD23615.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Seadorna_VP7 PF07387.11 PVD23615.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 PVD23615.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DnaJ PF00226.31 PVD23616.1 - 7.4e-08 32.4 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HAUS-augmin3 PF14932.6 PVD23617.1 - 2.3e-45 155.2 9.0 2.3e-45 155.2 9.0 2.4 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 GAS PF13851.6 PVD23617.1 - 0.0094 15.3 2.7 0.0094 15.3 2.7 3.6 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding MbeB_N PF04837.12 PVD23617.1 - 0.076 13.3 0.9 17 5.8 0.3 3.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF5446 PF17522.2 PVD23617.1 - 3.3 7.9 8.0 0.54 10.5 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5446) ACCA PF03255.14 PVD23617.1 - 9.8 6.0 7.7 5.9 6.8 0.3 3.3 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-C_C PF11699.8 PVD23618.1 - 1.5e-13 50.8 0.0 3.9e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 PVD23618.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain EF-hand_6 PF13405.6 PVD23619.1 - 2e-34 114.6 25.4 4e-06 26.3 0.0 8.0 7 1 1 8 8 8 6 EF-hand domain EF-hand_1 PF00036.32 PVD23619.1 - 2.8e-33 110.9 26.5 2.4e-07 29.8 0.1 7.5 8 0 0 8 8 8 6 EF hand EF-hand_7 PF13499.6 PVD23619.1 - 2.2e-32 111.3 26.4 6.6e-12 45.7 0.8 5.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 PVD23619.1 - 3.4e-18 65.2 22.7 8.5e-08 31.9 2.0 6.2 4 3 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 PVD23619.1 - 6.4e-18 63.4 31.6 8.4e-06 25.1 2.7 7.6 6 2 2 8 8 8 4 EF hand EF-hand_11 PF08976.11 PVD23619.1 - 0.00028 21.7 0.0 0.096 13.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PVD23619.1 - 0.00041 20.3 5.5 2 8.4 0.1 4.2 2 2 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 PVD23619.1 - 0.0011 18.9 0.3 0.32 10.9 0.0 2.8 2 1 1 3 3 3 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 PVD23619.1 - 0.0031 17.8 4.5 0.31 11.4 0.0 4.7 5 1 1 6 6 6 1 EF-hand domain p25-alpha PF05517.12 PVD23619.1 - 0.014 15.6 1.0 1 9.5 0.1 2.9 2 1 0 2 2 2 0 p25-alpha P-II PF00543.22 PVD23619.1 - 0.043 14.4 1.0 13 6.5 0.0 3.0 3 0 0 3 3 3 0 Nitrogen regulatory protein P-II HTH_54 PF18607.1 PVD23619.1 - 0.055 13.5 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 ParA helix turn helix domain Pam16 PF03656.13 PVD23619.1 - 0.077 13.0 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Pam16 EF-hand_14 PF17959.1 PVD23619.1 - 0.19 12.1 1.5 13 6.2 0.0 3.7 3 2 2 5 5 4 0 EF-hand domain DUF866 PF05907.13 PVD23620.1 - 6e-22 78.2 0.9 4.2e-12 46.2 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Rubredoxin PF00301.20 PVD23620.1 - 0.015 15.3 2.3 2.1 8.4 0.4 2.4 1 1 1 2 2 2 0 Rubredoxin zf-dskA_traR PF01258.17 PVD23620.1 - 0.084 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger DUF928 PF06051.12 PVD23620.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Pkinase PF00069.25 PVD23621.1 - 1.8e-76 257.0 0.0 2.3e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23621.1 - 1.1e-36 126.5 0.1 1.9e-36 125.7 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD23621.1 - 0.00027 20.0 0.1 0.00042 19.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PVD23621.1 - 0.051 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 PVD23621.1 - 0.057 12.7 0.0 0.17 11.2 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 PVD23621.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 PVD23622.1 - 1.1e-65 220.1 0.3 1.3e-65 220.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD23622.1 - 1.8e-35 121.8 0.3 2.4e-35 121.3 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD23622.1 - 2.5e-16 59.6 0.2 3e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD23622.1 - 2e-06 27.4 0.1 2.4e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD23622.1 - 8.4e-05 22.1 0.1 0.0001 21.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD23622.1 - 0.00037 20.1 0.3 0.0017 17.9 0.2 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD23622.1 - 0.00038 20.5 0.1 0.0006 19.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD23622.1 - 0.0032 17.4 0.3 0.75 9.7 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase DUF3963 PF13124.6 PVD23622.1 - 0.047 13.7 0.1 0.34 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) PduV-EutP PF10662.9 PVD23622.1 - 0.087 12.6 0.2 0.19 11.5 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PVD23622.1 - 0.21 12.0 0.0 0.24 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Tim17 PF02466.19 PVD23623.1 - 6.6e-06 26.5 9.3 1e-05 25.9 9.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MFS_2 PF13347.6 PVD23624.1 - 1.3e-96 323.8 23.2 1.5e-96 323.6 23.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 PVD23624.1 - 1.8e-14 53.4 13.8 2.3e-13 49.8 12.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Renin_r PF07850.14 PVD23624.1 - 0.013 16.0 1.7 0.34 11.5 0.0 2.9 2 0 0 2 2 2 0 Renin receptor-like protein RNF220 PF15926.5 PVD23627.1 - 2.8e-77 259.7 1.5 6e-77 258.6 1.5 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 PVD23627.1 - 2.7e-13 49.5 12.8 2.7e-13 49.5 12.8 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD23627.1 - 7.7e-05 22.5 9.6 7.7e-05 22.5 9.6 4.3 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD23627.1 - 0.00071 19.4 11.5 0.00071 19.4 11.5 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD23627.1 - 0.0015 18.4 10.3 0.0015 18.4 10.3 4.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD23627.1 - 0.0043 17.4 12.4 0.0043 17.4 12.4 4.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD23627.1 - 0.024 14.8 9.3 0.024 14.8 9.3 3.9 4 0 0 4 4 3 0 zinc finger of C3HC4-type, RING zf-C2H2_9 PF16293.5 PVD23627.1 - 0.044 13.6 4.1 5.9 6.8 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 PVD23627.1 - 0.094 13.6 15.2 2.6 9.1 0.1 5.3 3 1 2 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.12 PVD23627.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.7 3 1 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 PVD23627.1 - 0.33 11.0 21.2 0.15 12.2 10.0 3.3 3 0 0 3 3 3 0 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD23627.1 - 0.41 10.6 23.4 0.5 10.3 8.4 4.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 PVD23627.1 - 9.2 6.2 11.0 0.82 9.6 0.2 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif CoA_trans PF01144.23 PVD23631.1 - 6.9e-123 408.1 3.0 3.7e-77 258.6 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 PVD23631.1 - 0.00011 22.1 0.1 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Syntaxin PF00804.25 PVD23632.1 - 1e-15 58.0 10.3 1.4e-15 57.5 10.3 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 PVD23632.1 - 4e-09 36.3 10.7 4e-09 36.3 10.7 2.6 2 1 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 PVD23632.1 - 0.0011 18.8 0.7 0.39 10.5 0.2 2.8 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 PVD23632.1 - 0.0079 16.0 1.7 0.0079 16.0 1.7 3.0 3 0 0 3 3 3 1 Synaptobrevin Lge1 PF11488.8 PVD23632.1 - 0.027 14.6 0.3 0.027 14.6 0.3 2.8 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 NAGidase PF07555.13 PVD23632.1 - 1.6 8.0 5.7 0.21 10.9 0.9 1.8 2 1 1 3 3 3 0 beta-N-acetylglucosaminidase Troponin PF00992.20 PVD23632.1 - 2.9 8.2 11.1 0.076 13.3 3.3 2.3 3 1 0 3 3 3 0 Troponin Shisa PF13908.6 PVD23632.1 - 3 8.0 7.2 0.2 11.9 1.6 1.9 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Exonuc_VII_L PF02601.15 PVD23632.1 - 5.6 6.4 11.2 12 5.4 10.8 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 PVD23632.1 - 6 7.6 9.8 5.2 7.8 0.9 3.0 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF2951 PF11166.8 PVD23632.1 - 7.7 6.8 9.6 0.38 11.0 0.6 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2951) CoA_trans PF01144.23 PVD23633.1 - 1.3e-116 387.5 5.7 5.1e-73 245.1 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 PVD23633.1 - 7.7e-05 22.7 0.1 0.00013 21.9 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Dimer_Tnp_hAT PF05699.14 PVD23634.1 - 0.00063 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4874 PF16173.5 PVD23635.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Lipase PF00151.19 PVD23636.1 - 9.3e-13 48.2 0.0 1.1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 PVD23637.1 - 3.9e-75 253.3 1.1 5.1e-75 252.9 1.1 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 PVD23637.1 - 0.00027 21.5 0.1 0.00039 21.0 0.1 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain Lipase PF00151.19 PVD23638.1 - 3.2e-90 302.8 0.0 4.2e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 PVD23638.1 - 2.6e-11 44.1 0.0 4.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 PVD23638.1 - 0.0022 18.6 3.1 0.0022 18.6 3.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD23638.1 - 0.0074 16.0 0.2 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 PVD23638.1 - 0.044 13.3 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TGF_beta PF00019.20 PVD23639.1 - 3.3e-33 114.8 1.3 7.7e-33 113.6 1.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD23639.1 - 4.9e-26 92.0 0.1 8.8e-25 87.9 0.1 2.1 1 1 0 1 1 1 1 TGF-beta propeptide CRISPR_assoc PF08798.11 PVD23639.1 - 0.047 13.8 1.0 0.076 13.1 1.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein TSP_1 PF00090.19 PVD23640.1 - 5.2e-154 500.4 234.6 4.4e-14 52.4 9.6 15.1 14 0 0 14 14 14 14 Thrombospondin type 1 domain Lipase PF00151.19 PVD23640.1 - 7.4e-101 337.8 0.0 1.1e-100 337.3 0.0 1.2 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 PVD23640.1 - 6.4e-07 29.9 0.1 1.3e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Hepsin-SRCR PF09272.10 PVD23640.1 - 0.00012 22.6 0.0 0.00043 20.8 0.0 1.9 1 1 0 1 1 1 1 Hepsin, SRCR domain Abhydrolase_6 PF12697.7 PVD23640.1 - 0.00029 21.5 0.3 0.00073 20.2 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family EGF PF00008.27 PVD23640.1 - 0.0097 16.2 0.8 0.0097 16.2 0.8 5.5 4 1 0 4 4 4 1 EGF-like domain DUF900 PF05990.12 PVD23640.1 - 0.021 14.3 0.1 0.035 13.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 PVD23640.1 - 0.026 14.2 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD23640.1 - 0.11 11.7 0.3 0.18 11.0 0.3 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tctex-1 PF03645.13 PVD23641.1 - 8.3e-19 67.7 0.0 9.5e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF3289 PF11692.8 PVD23641.1 - 0.068 12.8 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) MT-A70 PF05063.14 PVD23643.1 - 1.4e-36 126.0 0.5 2.4e-35 122.0 0.0 2.2 2 0 0 2 2 2 1 MT-A70 N6-adenineMlase PF10237.9 PVD23643.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Amastin PF07344.11 PVD23644.1 - 0.0005 20.0 8.5 0.0005 20.0 8.5 2.3 1 1 1 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD23644.1 - 0.011 15.5 19.4 2.2 8.0 19.4 2.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD23644.1 - 0.019 14.9 13.6 0.043 13.7 13.6 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like EGF_MSP1_1 PF12946.7 PVD23644.1 - 0.58 10.3 2.3 2.5 8.2 0.2 2.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 L_HMGIC_fpl PF10242.9 PVD23644.1 - 0.63 10.2 14.6 7.4 6.7 14.6 2.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein 7tm_1 PF00001.21 PVD23645.1 - 1e-33 116.8 2.5 1.3e-33 116.4 2.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23645.1 - 2.6e-13 50.2 8.3 2.6e-13 50.2 8.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23645.1 - 8.5e-07 29.0 2.8 8.5e-07 29.0 2.8 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD23645.1 - 0.3 10.4 16.7 1.4 8.2 6.3 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD23646.1 - 7.2e-32 110.7 6.3 9.5e-32 110.3 6.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23646.1 - 2.1e-05 24.3 13.7 4.4e-05 23.2 13.7 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-RING-like PF08746.11 PVD23646.1 - 0.038 14.3 0.2 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 RING-like domain 7tm_1 PF00001.21 PVD23647.1 - 1.1e-22 80.6 16.9 1.5e-22 80.2 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD23648.1 - 5.1e-32 111.2 3.9 7.3e-32 110.7 3.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23648.1 - 2.2e-11 43.9 5.9 2.2e-11 43.9 5.9 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23648.1 - 1.3e-06 28.4 1.3 1.3e-06 28.4 1.3 2.0 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD23648.1 - 0.0084 15.5 11.8 0.016 14.6 1.0 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_1_2 PF00155.21 PVD23650.1 - 7.9e-07 28.6 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PVD23650.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 PVD23651.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DSL PF01414.19 PVD23652.1 - 2.3e-36 123.9 46.9 1.8e-14 53.7 6.8 12.4 10 2 4 14 14 14 4 Delta serrate ligand EGF PF00008.27 PVD23652.1 - 6.8e-20 71.0 103.5 1.8e-07 31.3 4.2 15.0 16 1 0 16 16 16 7 EGF-like domain hEGF PF12661.7 PVD23652.1 - 4.3e-09 36.7 26.5 6.5e-05 23.4 1.4 16.0 16 1 0 16 16 16 6 Human growth factor-like EGF SHP PF03579.13 PVD23653.1 - 0.077 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Small hydrophobic protein Adeno_E3_CR2 PF02439.15 PVD23653.1 - 0.13 12.0 2.3 0.27 11.0 2.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gemini_mov PF01708.16 PVD23653.1 - 0.16 11.8 0.2 0.87 9.4 0.0 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein PAP2 PF01569.21 PVD23654.1 - 8.4e-11 41.8 3.2 3.8e-09 36.4 3.2 2.5 1 1 0 1 1 1 1 PAP2 superfamily TetR_C_33 PF13305.6 PVD23654.1 - 0.1 13.3 0.1 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EptA_B_N PF08019.12 PVD23654.1 - 0.14 12.0 2.9 0.65 9.9 0.0 2.8 3 1 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB PAP2_C PF14360.6 PVD23654.1 - 7 7.3 7.7 0.25 11.9 0.4 2.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal ISK_Channel PF02060.15 PVD23657.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel RCR PF12273.8 PVD23657.1 - 0.021 15.4 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CSD PF00313.22 PVD23658.1 - 4.1e-09 36.2 0.0 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain ISK_Channel PF02060.15 PVD23659.1 - 0.016 14.9 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel RCR PF12273.8 PVD23659.1 - 0.021 15.5 0.0 0.028 15.1 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PRANC PF09372.10 PVD23660.1 - 0.064 13.6 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 PRANC domain Nudix_N PF12535.8 PVD23660.1 - 0.067 12.8 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal PA PF02225.22 PVD23661.1 - 5.8e-07 29.4 0.0 9.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PA domain BRCT PF00533.26 PVD23662.1 - 2.8e-21 75.7 2.5 1.4e-06 28.6 0.0 4.5 3 1 1 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD23662.1 - 2.2e-20 72.9 1.3 1.6e-07 31.6 0.0 4.8 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PVD23662.1 - 7.3e-20 70.7 0.7 9.4e-14 51.1 0.2 3.8 3 0 0 3 3 3 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 PVD23662.1 - 3.8e-08 33.1 0.5 3e-05 23.8 0.0 3.7 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 PVD23662.1 - 0.0054 16.8 0.6 5.4 7.2 0.1 3.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 PVD23662.1 - 0.015 15.6 1.5 0.097 13.0 0.1 3.0 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain DUF4738 PF15889.5 PVD23662.1 - 0.43 10.4 2.0 3.6 7.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) Aa_trans PF01490.18 PVD23663.1 - 6.3e-49 166.8 9.6 8e-49 166.4 9.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3611 PF12263.8 PVD23663.1 - 0.038 13.9 3.4 0.07 13.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) SLC3A2_N PF16028.5 PVD23663.1 - 0.15 11.7 3.1 0.4 10.3 3.1 1.7 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Pkinase PF00069.25 PVD23664.1 - 2.6e-55 187.6 0.4 7.1e-50 169.8 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23664.1 - 6.3e-31 107.6 0.0 1.3e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD23664.1 - 6e-06 25.5 0.3 1e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PVD23664.1 - 0.0003 20.2 0.1 0.00054 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD23664.1 - 0.00043 19.7 0.2 0.0019 17.6 0.2 2.0 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 PVD23664.1 - 0.072 12.1 0.5 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 PVD23664.1 - 0.25 11.2 3.7 0.64 9.9 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family HLH PF00010.26 PVD23665.1 - 2.6e-11 43.3 0.0 4.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 PVD23666.1 - 3e-16 59.1 0.1 5.8e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPP_enzyme_M_2 PF16582.5 PVD23668.1 - 0.066 12.9 0.2 1.7 8.3 0.0 2.0 1 1 1 2 2 2 0 Middle domain of thiamine pyrophosphate AMP-binding PF00501.28 PVD23671.1 - 2.8e-92 309.5 0.0 3.4e-92 309.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD23671.1 - 1.7e-21 76.9 0.1 3.1e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PVD23671.1 - 4.9e-19 68.0 0.2 1.4e-18 66.5 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Smg8_Smg9 PF10220.9 PVD23672.1 - 9.5 4.4 9.7 7.1 4.8 8.1 1.5 2 0 0 2 2 2 0 Smg8_Smg9 DUF1754 PF08555.10 PVD23673.1 - 5.3e-06 27.1 23.6 0.0033 18.2 23.6 2.2 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) NCKAP5 PF15246.6 PVD23673.1 - 0.0052 16.4 9.0 0.0064 16.1 9.0 1.2 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein UPF0160 PF03690.13 PVD23673.1 - 0.04 13.6 0.6 0.048 13.3 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Dishevelled PF02377.15 PVD23673.1 - 0.068 13.6 3.7 0.082 13.4 3.7 1.1 1 0 0 1 1 1 0 Dishevelled specific domain ATP-synt_DE PF00401.20 PVD23673.1 - 0.12 12.6 0.8 0.12 12.6 0.8 1.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SPATA6 PF14909.6 PVD23674.1 - 3.1e-52 176.4 0.0 4.7e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 AP_endonuc_2 PF01261.24 PVD23675.1 - 2.5e-08 33.6 0.1 2.4e-05 23.9 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Tctex-1 PF03645.13 PVD23676.1 - 3.7e-24 84.9 0.3 5e-24 84.5 0.3 1.2 1 0 0 1 1 1 1 Tctex-1 family SBP_bac_5 PF00496.22 PVD23676.1 - 0.039 12.9 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle cNMPbd_u2 PF16643.5 PVD23676.1 - 0.083 13.3 1.8 0.089 13.2 0.9 1.5 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein PAP_assoc PF03828.19 PVD23677.1 - 1.6e-27 95.5 0.1 1.2e-13 51.0 0.1 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PVD23677.1 - 1.1e-07 32.0 0.1 2.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC PF00098.23 PVD23677.1 - 5.5e-06 26.2 9.4 0.0014 18.6 2.5 2.7 2 0 0 2 2 2 2 Zinc knuckle Polbeta PF18765.1 PVD23677.1 - 0.00066 19.7 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase zf-C2H2_10 PF16588.5 PVD23677.1 - 0.015 15.0 0.2 0.015 15.0 0.2 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 PVD23677.1 - 0.21 11.5 4.1 0.81 9.6 4.1 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 PVD23677.1 - 0.86 9.5 15.0 0.022 14.6 2.0 3.0 3 0 0 3 3 3 0 Zinc knuckle EloA-BP1 PF15870.5 PVD23678.1 - 9.6e-55 185.3 0.4 9.6e-55 185.3 0.4 5.1 3 1 1 4 4 4 1 ElonginA binding-protein 1 Ank_2 PF12796.7 PVD23680.1 - 4.4e-29 100.9 6.8 5.9e-15 55.6 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23680.1 - 2.5e-19 69.1 2.5 1.1e-10 41.5 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23680.1 - 4.5e-15 54.3 3.5 1.3e-05 25.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PVD23680.1 - 1.8e-14 53.8 1.3 8.1e-10 39.0 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD23680.1 - 2.8e-14 52.8 2.6 6.2e-06 26.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat KN_motif PF12075.8 PVD23680.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 KN motif Pro_isomerase PF00160.21 PVD23681.1 - 7e-51 172.6 0.1 1.2e-50 171.8 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 PVD23681.1 - 1.6e-09 38.2 0.0 0.062 14.2 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23681.1 - 0.001 19.3 0.0 0.48 10.8 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD23681.1 - 0.027 13.4 0.1 3.1 6.7 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SR-25 PF10500.9 PVD23681.1 - 0.047 13.3 10.6 0.072 12.7 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Protocadherin PF08374.11 PVD23682.1 - 0.036 14.0 2.1 0.047 13.7 2.1 1.4 1 1 0 1 1 1 0 Protocadherin 2-oxoacid_dh PF00198.23 PVD23682.1 - 0.089 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) FlaG PF03646.15 PVD23682.1 - 0.24 11.6 2.6 0.26 11.5 1.2 1.8 1 1 1 2 2 2 0 FlaG protein Acyl_transf_3 PF01757.22 PVD23683.1 - 1e-15 57.7 25.9 1e-15 57.7 25.9 1.5 2 0 0 2 2 2 1 Acyltransferase family CD34_antigen PF06365.12 PVD23683.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Pro_isomerase PF00160.21 PVD23684.1 - 1.8e-49 168.0 0.1 3e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PVD23684.1 - 3.2e-14 52.5 0.0 5.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD23684.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Ank_2 PF12796.7 PVD23686.1 - 7.8e-18 64.8 0.1 6.2e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23686.1 - 1.4e-15 57.2 0.4 1.4e-06 28.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD23686.1 - 2.1e-13 50.5 0.2 6.5e-10 39.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD23686.1 - 2.5e-12 46.6 0.1 3.5e-06 27.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PVD23686.1 - 3.7e-11 42.2 0.1 2.4e-05 24.4 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Reeler PF02014.16 PVD23687.1 - 5.8e-28 98.2 0.2 8.9e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 Reeler domain UPRTase PF14681.6 PVD23688.1 - 4.5e-72 241.8 0.0 6.3e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 PVD23688.1 - 2.1e-32 112.4 0.1 3.1e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Polysacc_deac_1 PF01522.21 PVD23689.1 - 1.4e-11 44.3 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 PVD23690.1 - 1.5e-12 47.5 0.0 4.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase CBM_14 PF01607.24 PVD23690.1 - 9.9e-08 32.0 6.6 3.3e-07 30.3 6.6 2.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Neuroparsin PF07327.11 PVD23690.1 - 0.06 13.8 1.2 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Neuroparsin Mucin PF01456.17 PVD23690.1 - 0.24 11.4 17.6 0.46 10.5 17.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 PVD23691.1 - 1.3 7.5 5.8 3.2 6.2 5.7 1.5 1 1 0 1 1 1 0 Macoilin family Glyco_hydro_1 PF00232.18 PVD23692.1 - 3.2e-161 536.8 5.0 3.7e-161 536.6 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 EF-hand_7 PF13499.6 PVD23693.1 - 1.8e-20 73.2 34.7 3.5e-07 30.6 1.3 4.4 1 1 4 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 PVD23693.1 - 5.5e-20 69.4 13.3 0.0025 17.2 0.2 5.5 5 0 0 5 5 5 5 EF hand EF-hand_5 PF13202.6 PVD23693.1 - 5.1e-16 57.4 15.3 0.00034 20.0 0.2 5.8 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 PVD23693.1 - 3.5e-14 52.4 11.5 0.0094 15.8 0.2 4.8 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD23693.1 - 3.4e-13 48.4 9.9 0.039 13.9 0.3 5.5 5 0 0 5 5 5 5 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD23693.1 - 3.4e-06 27.3 9.9 0.003 17.9 0.4 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region AvrM_N PF18247.1 PVD23693.1 - 0.0069 16.3 1.2 0.37 10.8 0.2 2.6 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain RNase_T PF00929.24 PVD23693.1 - 0.0078 16.8 3.4 0.042 14.4 0.2 2.1 1 1 1 2 2 2 1 Exonuclease EF-hand_4 PF12763.7 PVD23693.1 - 0.022 14.7 9.2 0.36 10.8 0.4 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand OAM_dimer PF16554.5 PVD23693.1 - 0.12 12.8 0.4 0.57 10.7 0.0 2.2 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase PDEase_I PF00233.19 PVD23694.1 - 7.1e-75 251.8 3.8 5.8e-74 248.8 3.6 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PVD23694.1 - 1.1e-23 84.4 0.0 2.1e-16 60.8 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PVD23694.1 - 2.2e-16 60.4 0.0 4.7e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 PVD23694.1 - 6.6e-10 39.4 0.0 1.1e-06 29.0 0.0 2.8 2 1 0 2 2 2 2 GAF domain DUF484 PF04340.12 PVD23694.1 - 0.0011 18.7 0.6 0.069 12.8 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function, DUF484 SpoVT_C PF15714.5 PVD23694.1 - 0.038 14.0 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor YvfG PF09628.10 PVD23694.1 - 0.3 11.5 1.7 0.49 10.8 0.6 1.9 2 0 0 2 2 2 0 YvfG protein PAP2 PF01569.21 PVD23696.1 - 2.6e-24 85.5 2.2 6e-24 84.3 2.2 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 PVD23696.1 - 2.5e-08 33.8 3.1 4.5e-07 29.7 3.1 2.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 PVD23696.1 - 0.00054 20.4 4.4 0.00054 20.4 4.4 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal BRI3BP PF14965.6 PVD23696.1 - 0.04 13.5 0.7 0.04 13.5 0.7 1.9 2 1 0 2 2 2 0 Negative regulator of p53/TP53 Virul_fac_BrkB PF03631.15 PVD23696.1 - 0.11 12.1 6.6 0.94 9.0 1.3 2.3 2 0 0 2 2 2 0 Virulence factor BrkB DUF4203 PF13886.6 PVD23696.1 - 0.2 11.3 6.8 0.03 14.0 2.1 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) SPRY PF00622.28 PVD23697.1 - 4.4e-21 75.2 0.5 1.2e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 SPRY domain SOCS_box PF07525.16 PVD23697.1 - 1.1e-06 28.9 0.6 2.3e-06 27.9 0.2 1.7 2 0 0 2 2 2 1 SOCS box DUF974 PF06159.13 PVD23698.1 - 7.3e-63 212.6 0.0 1.2e-62 211.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 PVD23698.1 - 0.16 11.3 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 DUF3876 PF12992.7 PVD23700.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) SBF PF01758.16 PVD23701.1 - 5.7e-16 58.8 12.7 2e-15 57.0 9.7 2.5 1 1 1 2 2 2 2 Sodium Bile acid symporter family Arf PF00025.21 PVD23703.1 - 1e-65 220.5 11.0 2.1e-27 95.7 0.6 3.6 3 1 1 4 4 4 3 ADP-ribosylation factor family Ras PF00071.22 PVD23703.1 - 3.7e-11 42.9 3.3 0.003 17.2 0.0 3.5 2 2 1 3 3 3 3 Ras family SRPRB PF09439.10 PVD23703.1 - 0.00013 21.5 6.8 0.51 9.8 0.1 3.3 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit PCSK9_C3 PF18463.1 PVD23703.1 - 0.00017 21.8 1.1 1.1 9.5 0.1 3.2 2 0 0 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain MMR_HSR1_Xtn PF16897.5 PVD23703.1 - 0.00017 21.5 0.9 0.32 11.0 0.1 2.6 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain NOG1 PF06858.14 PVD23703.1 - 0.00029 20.5 1.2 1.3 8.9 0.1 3.2 2 0 0 2 2 2 2 Nucleolar GTP-binding protein 1 (NOG1) Gtr1_RagA PF04670.12 PVD23703.1 - 0.0033 16.8 12.9 0.43 9.9 1.0 3.6 2 2 2 4 4 4 2 Gtr1/RagA G protein conserved region CbiG_C PF01890.16 PVD23703.1 - 0.0044 17.6 2.7 9.4 6.8 0.0 3.7 3 1 0 3 3 3 1 Cobalamin synthesis G C-terminus SRI PF08236.11 PVD23703.1 - 0.012 15.7 2.5 1.3 9.2 0.6 2.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Roc PF08477.13 PVD23703.1 - 0.013 15.7 0.6 0.13 12.4 0.1 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase C1ORF64 PF15547.6 PVD23703.1 - 0.074 13.5 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein NACHT PF05729.12 PVD23703.1 - 0.087 12.7 5.9 0.93 9.4 0.0 2.8 2 2 0 2 2 2 0 NACHT domain Gly_radical PF01228.21 PVD23703.1 - 0.18 12.4 0.5 28 5.3 0.1 2.5 2 0 0 2 2 2 0 Glycine radical AAA_14 PF13173.6 PVD23703.1 - 0.28 11.2 1.6 0.56 10.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 PVD23703.1 - 0.48 9.5 10.1 8.6 5.4 0.1 3.8 3 1 0 4 4 4 0 G-protein alpha subunit ABC_tran PF00005.27 PVD23703.1 - 0.8 10.2 3.7 4.9 7.7 0.0 3.1 2 1 1 3 3 3 0 ABC transporter DUF3008 PF11450.8 PVD23703.1 - 1.4 9.2 6.9 1.2e+02 3.0 0.2 4.5 4 0 0 4 4 4 0 Protein of unknwon function (DUF3008) Toxin_30 PF08117.11 PVD23703.1 - 1.6 9.0 5.1 26 5.2 0.4 2.6 2 0 0 2 2 2 0 Ptu family Arf PF00025.21 PVD23705.1 - 1.3e-28 99.7 0.4 1.5e-28 99.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PVD23705.1 - 0.00011 21.9 0.1 0.00013 21.6 0.1 1.0 1 0 0 1 1 1 1 Ras family NOG1 PF06858.14 PVD23705.1 - 0.0055 16.5 0.2 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 PVD23705.1 - 0.022 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 PVD23705.1 - 0.033 13.5 0.1 0.037 13.4 0.1 1.0 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PCSK9_C3 PF18463.1 PVD23705.1 - 0.055 13.7 1.6 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain SRPRB PF09439.10 PVD23705.1 - 0.076 12.4 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit COX14 PF14880.6 PVD23706.1 - 0.16 11.8 0.4 0.48 10.3 0.4 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly TPR_2 PF07719.17 PVD23707.1 - 0.00042 20.2 2.0 0.048 13.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD23707.1 - 0.0024 18.6 0.0 0.19 12.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD23707.1 - 0.045 14.0 1.0 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PGP_phosphatase PF09419.10 PVD23707.1 - 0.084 12.5 0.2 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase TPR_10 PF13374.6 PVD23707.1 - 0.091 12.7 1.0 0.47 10.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD23707.1 - 0.2 11.5 3.3 2.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_15 PF12324.8 PVD23707.1 - 0.21 11.6 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase CARD PF00619.21 PVD23708.1 - 1e-12 47.9 0.4 5.8e-12 45.5 0.4 2.4 1 0 0 1 1 1 1 Caspase recruitment domain SAM_2 PF07647.17 PVD23708.1 - 2.1e-06 27.7 0.0 6.3e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD23708.1 - 0.00088 19.7 0.0 0.003 17.9 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AlbA_2 PF04326.14 PVD23708.1 - 0.0093 16.3 0.1 0.13 12.5 0.0 2.9 2 0 0 2 2 2 1 Putative DNA-binding domain SAM_Ste50p PF09235.10 PVD23708.1 - 0.044 14.0 0.1 0.17 12.1 0.1 2.1 1 0 0 1 1 1 0 Ste50p, sterile alpha motif TPR_14 PF13428.6 PVD23708.1 - 0.048 14.5 0.4 0.25 12.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 PVD23708.1 - 5.5 7.3 7.2 2 8.7 1.0 3.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4277 PF14104.6 PVD23709.1 - 0.00079 19.8 0.1 0.23 11.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4277) SYCP2_ARLD PF18581.1 PVD23709.1 - 0.16 11.9 1.7 0.34 10.9 0.6 2.2 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain BTB PF00651.31 PVD23710.1 - 2.4e-21 76.0 0.3 5.3e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD23710.1 - 2.8e-16 59.5 1.1 2.8e-16 59.5 1.1 2.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD23710.1 - 3.1e-15 55.5 9.3 2.5e-06 27.0 0.1 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_6 PF13964.6 PVD23710.1 - 2.6e-12 46.5 3.2 7.1e-05 22.9 0.0 4.9 5 1 1 6 6 6 2 Kelch motif Kelch_3 PF13415.6 PVD23710.1 - 3.5e-07 30.3 1.3 0.0039 17.4 0.2 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD23710.1 - 6.6e-05 22.7 7.6 0.52 10.4 3.6 4.3 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD23710.1 - 0.00023 21.1 3.2 0.024 14.6 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3342 PF11822.8 PVD23710.1 - 0.024 14.8 1.2 0.042 14.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) CCM2_C PF16545.5 PVD23711.1 - 2.2e-19 69.8 0.1 7.9e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology PID PF00640.23 PVD23711.1 - 0.0063 16.5 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF3652 PF12372.8 PVD23712.1 - 0.15 12.0 0.3 0.53 10.2 0.3 1.9 1 0 0 1 1 1 0 Huntingtin protein region F5_F8_type_C PF00754.25 PVD23714.1 - 4.4e-06 26.8 0.0 5.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 PVD23714.1 - 7.7e-06 26.0 0.4 1.4e-05 25.2 0.4 1.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal XRCC1_N PF01834.16 PVD23714.1 - 3.5e-05 23.8 0.1 4e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 XRCC1 N terminal domain ANAPC10 PF03256.16 PVD23714.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) zf-C2H2 PF00096.26 PVD23715.1 - 3.4e-16 58.7 30.3 0.00062 20.1 0.7 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD23715.1 - 1.1e-10 41.4 23.1 5.5e-05 23.4 0.6 5.7 5 0 0 5 5 5 3 Zinc-finger double domain TFIIA PF03153.13 PVD23715.1 - 0.0014 18.7 12.7 0.0014 18.7 12.7 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_8 PF15909.5 PVD23715.1 - 0.0095 16.2 16.4 0.038 14.3 0.7 3.6 3 1 0 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 PVD23715.1 - 0.017 15.9 44.4 0.019 15.8 0.7 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger FOXP-CC PF16159.5 PVD23715.1 - 0.17 12.6 0.2 0.17 12.6 0.2 6.6 4 1 4 8 8 8 0 FOXP coiled-coil domain Calpain_inhib PF00748.19 PVD23715.1 - 1.1 9.8 4.0 4 7.9 4.0 2.0 1 0 0 1 1 1 0 Calpain inhibitor zf-C2H2_aberr PF17017.5 PVD23715.1 - 1.8 8.7 11.2 27 4.9 0.1 4.2 1 1 4 5 5 5 0 Aberrant zinc-finger Ndc1_Nup PF09531.10 PVD23717.1 - 1.1e-41 143.3 0.5 2.7e-40 138.7 0.5 2.0 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RFX_DNA_binding PF02257.15 PVD23718.1 - 5.7e-33 113.4 0.5 1.5e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 PVD23718.1 - 0.023 15.2 0.1 0.088 13.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus D5 protein-like HisKA PF00512.25 PVD23718.1 - 0.044 13.8 2.9 0.52 10.4 0.2 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF2258 PF10015.9 PVD23718.1 - 0.18 12.0 0.1 0.47 10.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) SLATT_1 PF18181.1 PVD23718.1 - 0.76 9.7 3.6 0.79 9.7 0.9 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Ctr PF04145.15 PVD23719.1 - 2.3e-15 57.5 14.4 7.4e-13 49.4 10.7 2.1 1 1 1 2 2 2 2 Ctr copper transporter family DUF1516 PF07457.11 PVD23719.1 - 0.062 13.5 2.2 0.11 12.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) FA_desaturase PF00487.24 PVD23719.1 - 0.43 10.4 3.1 0.53 10.1 3.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase RseC_MucC PF04246.12 PVD23719.1 - 0.45 10.5 7.4 1.7 8.6 4.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ctr PF04145.15 PVD23720.1 - 8e-21 75.2 12.9 2.1e-15 57.7 5.0 2.2 1 1 1 2 2 2 2 Ctr copper transporter family DUF1218 PF06749.12 PVD23720.1 - 0.0057 17.1 1.8 0.01 16.4 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1218) MTABC_N PF16185.5 PVD23720.1 - 0.024 14.2 1.8 0.03 13.8 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Lys_export PF03956.13 PVD23720.1 - 0.063 12.8 4.8 0.083 12.4 4.8 1.1 1 0 0 1 1 1 0 Lysine exporter LysO AA_permease_C PF13906.6 PVD23720.1 - 0.45 10.6 4.7 1 9.5 4.7 1.7 1 0 0 1 1 1 0 C-terminus of AA_permease UCH PF00443.29 PVD23721.1 - 9.9e-48 162.9 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD23721.1 - 5.8e-13 49.1 0.1 5.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PVD23721.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 PVD23721.1 - 0.003 17.1 0.1 0.0092 15.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ras PF00071.22 PVD23723.1 - 2.2e-33 115.2 0.2 3.3e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD23723.1 - 2.7e-17 63.1 0.8 5e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD23723.1 - 1.6e-06 27.7 0.3 2.4e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD23723.1 - 0.001 18.7 0.4 0.0012 18.4 0.4 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 PVD23723.1 - 0.031 14.3 0.3 0.062 13.3 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 PVD23723.1 - 0.036 14.0 0.2 0.071 13.0 0.2 1.4 1 1 0 1 1 1 0 RsgA GTPase FeoB_Cyto PF17910.1 PVD23723.1 - 0.17 12.4 1.0 1.2 9.7 0.4 2.2 1 1 1 2 2 2 0 FeoB cytosolic helical domain Vasculin PF15337.6 PVD23724.1 - 7.8e-16 58.7 3.2 2.4e-15 57.1 3.2 1.9 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 G-patch_2 PF12656.7 PVD23724.1 - 0.77 9.9 0.0 0.77 9.9 0.0 3.0 4 0 0 4 4 4 0 G-patch domain EF-hand_2 PF09068.11 PVD23725.1 - 1.1e-26 93.4 0.7 2.4e-26 92.3 0.7 1.6 1 0 0 1 1 1 1 EF hand ZZ PF00569.17 PVD23725.1 - 2e-13 49.9 12.8 5.9e-13 48.4 12.8 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type WW PF00397.26 PVD23725.1 - 2.7e-05 24.2 0.4 5.9e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 WW domain Peptidase_M3 PF01432.20 PVD23726.1 - 1e-152 509.6 0.0 1.4e-152 509.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 PVD23726.1 - 0.014 14.1 3.2 0.0092 14.7 1.1 1.7 2 0 0 2 2 2 0 Angiotensin-converting enzyme PhaP_Bmeg PF09602.10 PVD23726.1 - 0.016 15.2 0.3 0.034 14.1 0.3 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CRM1_C PF08767.11 PVD23727.1 - 0.0025 17.1 2.2 0.0025 17.1 2.2 2.7 3 0 0 3 3 3 1 CRM1 C terminal IBN_N PF03810.19 PVD23728.1 - 0.00039 20.3 0.1 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain EST1_DNA_bind PF10373.9 PVD23728.1 - 0.046 13.2 4.7 0.035 13.6 2.6 1.8 1 1 1 2 2 2 0 Est1 DNA/RNA binding domain MFS_1 PF07690.16 PVD23729.1 - 1e-20 74.0 28.8 1.6e-15 56.9 11.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily KH_1 PF00013.29 PVD23731.1 - 3.4e-08 33.2 0.0 7.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 PVD23731.1 - 1.5e-05 24.7 0.3 1.5e-05 24.7 0.3 2.0 2 1 0 2 2 2 1 Qua1 domain Orn_Arg_deC_N PF02784.16 PVD23732.1 - 1e-77 260.9 0.0 1.3e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD23732.1 - 1.3e-15 57.4 0.0 1.5e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LRR_4 PF12799.7 PVD23734.1 - 1.4e-06 28.5 8.9 0.00025 21.4 0.6 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD23734.1 - 1.9e-06 27.5 0.0 7.4e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD23734.1 - 0.046 13.5 9.8 0.74 9.6 7.5 3.1 2 1 2 4 4 4 0 Leucine rich repeat Ank_2 PF12796.7 PVD23735.1 - 1.2e-33 115.6 12.6 8e-11 42.4 0.7 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23735.1 - 4.7e-29 100.1 15.9 2.2e-06 27.8 0.4 6.3 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23735.1 - 6.3e-28 93.7 13.8 0.0039 17.6 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 PVD23735.1 - 1.9e-27 95.2 12.6 2.1e-08 34.6 0.1 6.9 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD23735.1 - 1.3e-24 85.5 27.2 0.0035 17.7 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat BP28CT PF08146.12 PVD23736.1 - 2.9e-39 134.4 5.6 1.3e-38 132.3 5.6 2.3 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 PVD23736.1 - 0.00079 19.8 0.4 0.00079 19.8 0.4 6.3 7 2 1 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 PVD23736.1 - 0.018 15.4 11.1 0.4 11.1 0.0 4.9 6 0 0 6 6 6 0 HEAT repeats Ribosomal_S5_C PF03719.15 PVD23736.1 - 0.086 12.3 0.0 4.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain DUF445 PF04286.12 PVD23736.1 - 0.31 10.8 9.1 0.24 11.2 2.6 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) CABIT PF12736.7 PVD23737.1 - 6.3e-07 29.0 0.0 0.00057 19.3 0.0 3.1 2 1 1 3 3 3 3 Cell-cycle sustaining, positive selection, G-gamma PF00631.22 PVD23738.1 - 4.4e-17 61.9 0.0 5.2e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain 7tm_2 PF00002.24 PVD23739.1 - 6.4e-40 137.0 8.9 1.4e-35 122.8 4.1 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) GAIN PF16489.5 PVD23739.1 - 2.9e-25 89.0 1.5 4.4e-25 88.4 1.5 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Lectin_C PF00059.21 PVD23739.1 - 3.2e-17 63.2 0.7 3.2e-17 63.2 0.7 2.8 3 0 0 3 3 3 1 Lectin C-type domain GPS PF01825.21 PVD23739.1 - 3.8e-16 59.3 4.7 1.2e-15 57.7 4.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 PVD23739.1 - 0.0022 17.2 6.6 0.0059 15.8 6.6 1.7 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor INO80_Ies4 PF08193.11 PVD23739.1 - 6.7 6.6 16.8 6 6.8 14.1 2.2 2 0 0 2 2 2 0 INO80 complex subunit Ies4 UL45 PF05473.12 PVD23740.1 - 2.7e-11 43.5 1.1 3.5e-11 43.1 1.1 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD23740.1 - 2.7e-10 40.9 5.4 6.9e-10 39.6 5.4 1.7 1 1 0 1 1 1 1 Lectin C-type domain VWD PF00094.25 PVD23741.1 - 0.0017 18.6 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type D domain EB PF01683.18 PVD23741.1 - 0.14 12.5 19.7 0.095 13.0 3.0 2.9 2 0 0 2 2 2 0 EB module TM2 PF05154.16 PVD23742.1 - 2.6e-12 46.9 11.6 6.6e-11 42.4 9.4 3.1 3 0 0 3 3 3 1 TM2 domain GNT-I PF03071.15 PVD23743.1 - 3e-28 98.8 2.1 7.6e-17 61.2 0.3 2.9 1 1 1 2 2 2 2 GNT-I family ILEI PF15711.5 PVD23743.1 - 4.7e-25 87.9 0.2 1e-24 86.8 0.2 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer PAM2 PF07145.15 PVD23743.1 - 7.5 6.5 7.2 0.56 10.0 1.9 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region PDZ PF00595.24 PVD23744.1 - 2e-180 585.6 49.5 5.6e-20 71.5 0.2 12.4 12 0 0 12 12 12 12 PDZ domain PDZ_6 PF17820.1 PVD23744.1 - 5.5e-93 304.7 38.7 2.6e-10 40.0 0.1 12.5 12 0 0 12 12 12 12 PDZ domain PDZ_2 PF13180.6 PVD23744.1 - 6.2e-49 164.3 32.5 0.00068 19.9 0.0 12.6 12 0 0 12 12 12 12 PDZ domain Tricorn_PDZ PF14685.6 PVD23744.1 - 6.3e-06 26.1 16.3 6.9 6.7 0.1 9.2 10 0 0 10 10 10 2 Tricorn protease PDZ domain TMEM252 PF15664.5 PVD23744.1 - 0.74 9.5 6.7 4.7 6.9 0.7 2.7 1 1 0 2 2 2 0 Transmembrane protein 252 family TMEM52 PF14979.6 PVD23744.1 - 4.1 7.3 5.4 3.8 7.4 1.8 2.4 2 0 0 2 2 2 0 Transmembrane 52 DUF1488 PF07369.11 PVD23748.1 - 0.04 13.9 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) zf-C2H2_2 PF12756.7 PVD23749.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Sensor PF13796.6 PVD23749.1 - 0.5 10.4 3.5 0.81 9.7 3.5 1.3 1 0 0 1 1 1 0 Putative sensor L27_2 PF09045.10 PVD23750.1 - 7.4e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 L27_2 L27_1 PF09058.10 PVD23750.1 - 0.013 15.5 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 L27_1 PDZ PF00595.24 PVD23750.1 - 0.043 14.2 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.7 PVD23751.1 - 1.6e-50 169.6 3.2 1e-12 48.4 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD23751.1 - 7.5e-40 134.5 7.4 6.5e-08 32.7 0.1 7.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD23751.1 - 1.4e-39 134.0 4.8 5.9e-07 29.9 0.0 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23751.1 - 6e-36 118.4 9.2 0.00013 22.1 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 PVD23751.1 - 3.4e-33 112.6 14.6 1.2e-05 25.6 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Rhomboid_N PF12122.8 PVD23751.1 - 0.078 13.2 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease PDZ PF00595.24 PVD23752.1 - 4.8e-22 78.1 4.2 5.8e-13 49.0 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD23752.1 - 1.6e-21 75.9 0.7 9.3e-14 51.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PVD23752.1 - 1.8e-12 47.4 0.6 3.1e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain DUF3394 PF11874.8 PVD23752.1 - 0.12 12.1 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) RPEL PF02755.15 PVD23754.1 - 2.5e-28 96.9 12.6 1.2e-07 31.2 2.1 4.5 4 0 0 4 4 4 4 RPEL repeat PRCC PF10253.9 PVD23754.1 - 0.0014 19.5 0.7 0.0014 19.5 0.7 4.2 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SieB PF14163.6 PVD23754.1 - 0.64 9.5 2.4 9.5 5.7 0.5 3.2 1 1 3 4 4 4 0 Super-infection exclusion protein B JmjC PF02373.22 PVD23755.1 - 2.7e-43 147.0 0.9 1.1e-42 145.0 0.3 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 PVD23755.1 - 1e-28 99.7 7.1 1e-28 99.7 7.1 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 PVD23755.1 - 1.4e-23 82.3 2.8 8.7e-12 44.5 0.1 2.6 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 PVD23755.1 - 1.1e-13 51.3 4.9 1.1e-13 51.3 4.9 3.1 2 1 1 3 3 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 PVD23755.1 - 5.8e-12 44.9 6.6 5.8e-12 44.9 6.6 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PVD23755.1 - 3e-05 23.8 14.6 0.0015 18.3 4.4 3.0 2 0 0 2 2 2 2 PHD-finger DUF4537 PF15057.6 PVD23755.1 - 7.1e-05 22.8 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 PVD23755.1 - 0.00012 21.9 0.1 0.0097 15.7 0.0 2.9 2 1 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 PVD23755.1 - 0.0052 16.6 0.3 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 PVD23755.1 - 0.0065 16.1 1.0 0.015 15.0 0.2 2.0 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 SM-ATX PF14438.6 PVD23755.1 - 0.083 13.0 0.0 0.53 10.5 0.0 2.4 2 0 0 2 2 1 0 Ataxin 2 SM domain PHD_4 PF16866.5 PVD23755.1 - 0.32 11.1 12.2 0.25 11.4 4.1 3.2 2 0 0 2 2 2 0 PHD-finger zinc_ribbon_4 PF13717.6 PVD23755.1 - 0.74 9.8 4.4 0.48 10.4 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain RT_RNaseH_2 PF17919.1 PVD23756.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD23756.1 - 0.0015 18.8 0.2 0.0036 17.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RINGv PF12906.7 PVD23757.1 - 2.9e-09 36.9 0.7 2.9e-09 36.9 0.7 1.6 2 0 0 2 2 2 1 RING-variant domain 7tm_1 PF00001.21 PVD23758.1 - 2.9e-08 33.4 2.4 3.8e-08 33.0 2.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23758.1 - 0.051 13.0 0.2 0.064 12.6 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx ATG16 PF08614.11 PVD23759.1 - 0.039 14.2 1.7 0.058 13.6 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) NHL PF01436.21 PVD23759.1 - 0.05 13.7 0.1 38 4.6 0.0 3.7 3 0 0 3 3 3 0 NHL repeat 7tm_1 PF00001.21 PVD23760.1 - 9.6e-39 133.3 14.1 1.2e-38 132.9 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23760.1 - 1.4e-07 31.2 9.4 1.8e-07 30.9 9.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD23760.1 - 3.9e-07 30.0 12.0 5.2e-07 29.6 12.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD23760.1 - 0.00012 21.5 12.6 0.00023 20.6 12.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 PVD23760.1 - 0.00015 21.6 7.8 0.00015 21.6 7.8 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 PVD23760.1 - 0.0042 16.4 10.5 0.0042 16.4 10.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD23761.1 - 1.6e-25 89.9 18.8 2e-25 89.6 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23761.1 - 1.2e-08 35.0 9.2 1.2e-08 35.0 9.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 PVD23761.1 - 0.14 11.1 11.7 0.022 13.7 8.2 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srbc PF10316.9 PVD23761.1 - 0.46 9.9 13.0 0.12 11.9 8.0 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc DUF1394 PF07159.12 PVD23764.1 - 3e-84 282.9 0.6 3.3e-84 282.7 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DEPP PF15343.6 PVD23764.1 - 0.04 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Decidual protein induced by progesterone family GatB_N PF02934.15 PVD23766.1 - 0.12 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 GatB/GatE catalytic domain HLH PF00010.26 PVD23769.1 - 2.5e-09 36.9 0.1 2.5e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DHR10 PF18595.1 PVD23769.1 - 2.3 8.3 10.3 6.3 6.9 2.7 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain IPPT PF01715.17 PVD23770.1 - 2.1e-60 204.4 0.0 3.6e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 IPP transferase zf-C2H2_2 PF12756.7 PVD23770.1 - 0.00016 21.9 1.0 0.00037 20.8 1.0 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PVD23770.1 - 0.00029 21.0 0.7 0.00079 19.6 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 PVD23770.1 - 0.0057 16.5 0.2 0.0057 16.5 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.7 PVD23770.1 - 0.016 15.6 0.2 0.056 13.9 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type OrsD PF12013.8 PVD23770.1 - 0.12 12.8 2.5 0.5 10.8 0.7 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D F-box-like PF12937.7 PVD23771.1 - 0.0097 15.8 0.5 0.052 13.5 0.4 2.2 2 0 0 2 2 2 1 F-box-like SelP_N PF04592.14 PVD23772.1 - 2e-19 69.9 5.4 1.2e-09 37.9 2.6 2.1 1 1 1 2 2 2 2 Selenoprotein P, N terminal region WD40 PF00400.32 PVD23773.1 - 8.6e-41 137.2 18.2 3.3e-06 27.7 0.1 11.2 11 0 0 11 11 11 7 WD domain, G-beta repeat TRAPP PF04051.16 PVD23773.1 - 1.7e-27 95.9 0.0 3e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ANAPC4_WD40 PF12894.7 PVD23773.1 - 5.4e-21 74.7 1.9 0.0081 16.4 0.1 9.4 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain SH3_1 PF00018.28 PVD23773.1 - 1e-09 37.8 0.2 3.2e-09 36.3 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD23773.1 - 6e-07 29.2 0.2 1.8e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ge1_WD40 PF16529.5 PVD23773.1 - 1.1e-06 27.8 2.8 0.11 11.4 0.2 5.4 2 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD23773.1 - 3.5e-06 27.0 0.6 0.13 12.1 0.1 3.6 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A SH3_2 PF07653.17 PVD23773.1 - 0.00013 21.5 0.0 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nup160 PF11715.8 PVD23773.1 - 0.0012 17.6 0.4 0.9 8.1 0.1 3.9 3 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ PF01011.21 PVD23773.1 - 0.021 14.7 0.4 0.28 11.2 0.2 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat WD40 PF00400.32 PVD23774.1 - 7e-18 64.7 13.3 4e-09 37.0 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD23774.1 - 9.7e-05 22.6 0.4 0.095 13.0 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD23774.1 - 0.012 14.6 0.8 0.8 8.6 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_alt PF14077.6 PVD23774.1 - 0.017 15.0 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif PTP_tm PF18861.1 PVD23775.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mastoparan_2 PF08251.11 PVD23775.1 - 0.13 12.5 2.3 0.33 11.3 2.3 1.7 1 0 0 1 1 1 0 Mastoparan peptide LRR_9 PF14580.6 PVD23776.1 - 1.1e-87 292.0 1.1 1.6e-87 291.5 1.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PVD23776.1 - 3.4e-06 27.3 15.0 0.006 17.0 4.7 3.9 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD23776.1 - 0.01 15.5 12.0 0.021 14.6 2.5 3.1 2 1 3 5 5 5 0 Leucine rich repeat PPP4R2 PF09184.11 PVD23776.1 - 0.5 9.9 14.2 0.62 9.6 14.2 1.1 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 PVD23776.1 - 2.2 6.3 17.0 2.6 6.0 17.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Orthoreo_P10 PF07204.11 PVD23778.1 - 0.013 15.5 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 PVD23778.1 - 0.24 12.3 0.5 0.46 11.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD23778.1 - 8.3 6.4 6.7 0.24 11.3 0.6 1.6 2 0 0 2 2 2 0 Syndecan domain IMUP PF15761.5 PVD23779.1 - 0.41 11.3 4.6 0.51 11.1 0.2 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein CARD PF00619.21 PVD23781.1 - 2.6e-07 30.5 0.2 3.8e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Caspase recruitment domain Dysbindin PF04440.16 PVD23781.1 - 0.04 14.1 0.2 0.052 13.7 0.2 1.4 1 1 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF630 PF04783.12 PVD23781.1 - 0.061 13.5 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Methyltransf_28 PF02636.17 PVD23781.1 - 0.087 12.4 0.0 0.61 9.7 0.0 1.9 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TraB PF01963.17 PVD23783.1 - 7.4e-23 81.8 0.0 8.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 TraB family TraB PF01963.17 PVD23784.1 - 5.2e-20 72.4 0.0 1.5e-19 70.9 0.0 1.7 2 0 0 2 2 2 1 TraB family Aquarius_N PF16399.5 PVD23785.1 - 0 1014.2 3.8 0 1013.8 3.8 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 PVD23785.1 - 1.4e-28 100.4 0.0 2.9e-28 99.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 PVD23785.1 - 9.7e-25 87.3 0.0 2.4e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD23785.1 - 3.3e-08 34.0 0.2 7.5e-07 29.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD23785.1 - 1.2e-05 25.2 0.0 0.005 16.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 PVD23785.1 - 7.5e-05 22.8 0.1 0.00039 20.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD23785.1 - 0.00016 21.5 0.1 0.00091 19.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 PVD23785.1 - 0.0047 16.2 0.3 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RecA PF00154.21 PVD23785.1 - 0.0056 16.2 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 PVD23785.1 - 0.0087 16.5 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 PVD23785.1 - 0.011 15.3 0.1 0.044 13.3 0.0 2.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 PVD23785.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 PVD23785.1 - 0.022 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UvrD_C_2 PF13538.6 PVD23785.1 - 0.024 14.5 0.3 0.052 13.4 0.3 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DnaB_C PF03796.15 PVD23785.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 PVD23785.1 - 0.047 14.0 0.4 0.55 10.5 0.4 2.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD23785.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 PVD23785.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC Viral_helicase1 PF01443.18 PVD23785.1 - 0.2 11.4 0.1 7.1 6.3 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Tfb5 PF06331.12 PVD23785.1 - 0.27 11.3 1.8 3.8 7.6 0.2 2.5 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 LSM PF01423.22 PVD23786.1 - 8e-14 51.1 0.0 1.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 PVD23786.1 - 6.5 7.5 33.2 11 6.8 33.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ofd1_CTDD PF10637.9 PVD23787.1 - 2.8e-41 141.6 0.0 7e-40 137.0 0.0 2.3 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 PVD23787.1 - 1.9e-31 108.6 0.1 1.9e-26 92.5 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 PVD23787.1 - 2.8e-14 53.7 0.1 3.8e-12 47.0 0.0 2.8 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily RNA_pol_Rpb1_5 PF04998.17 PVD23788.1 - 4.8e-93 311.5 0.3 1e-92 310.4 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PVD23788.1 - 8.1e-66 221.3 0.0 2.2e-65 219.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PVD23788.1 - 1.3e-33 116.2 0.0 8.9e-33 113.4 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 PVD23788.1 - 3.5e-33 115.3 1.8 3.2e-32 112.1 0.1 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 PVD23788.1 - 1.1e-22 80.0 0.1 4.2e-22 78.1 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2368 PF10166.9 PVD23789.1 - 3.6e-43 146.4 0.1 4.3e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Pkinase PF00069.25 PVD23790.1 - 1.6e-19 70.3 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23790.1 - 4.5e-11 42.5 0.0 7.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Profilin PF00235.19 PVD23791.1 - 0.0028 17.9 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 Profilin CPSase_L_D2 PF02786.17 PVD23792.1 - 2.4e-109 363.8 0.5 1.8e-82 275.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 PVD23792.1 - 6e-51 171.6 0.0 1.3e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 PVD23792.1 - 5.6e-45 153.0 0.0 1.1e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 PVD23792.1 - 3e-42 144.5 0.0 8.6e-42 143.1 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 PVD23792.1 - 4e-36 124.0 0.1 9.5e-36 122.8 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 PVD23792.1 - 8.2e-35 120.2 0.0 2.4e-34 118.7 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 PVD23792.1 - 9.6e-17 61.0 0.0 5.3e-16 58.6 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 PVD23792.1 - 1.2e-16 60.9 1.0 2e-07 30.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PVD23792.1 - 5.5e-16 58.6 0.5 2.2e-09 37.1 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain Amidohydro_1 PF01979.20 PVD23792.1 - 8.2e-10 38.5 0.3 2.9e-09 36.7 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase family ATPgrasp_Ter PF15632.6 PVD23792.1 - 1e-09 38.2 0.1 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PVD23792.1 - 1.2e-07 31.9 0.4 0.00038 20.5 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 PVD23792.1 - 2.7e-06 27.3 0.1 0.00032 20.5 0.1 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 PVD23792.1 - 0.0013 18.6 0.0 0.79 9.5 0.0 3.5 3 0 0 3 3 3 1 DJ-1/PfpI family Ish1 PF10281.9 PVD23792.1 - 0.017 15.4 0.5 5 7.5 0.2 3.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein ATP-grasp_5 PF13549.6 PVD23792.1 - 0.047 13.1 0.1 4.3 6.7 0.2 2.4 2 0 0 2 2 2 0 ATP-grasp domain C1q PF00386.21 PVD23793.1 - 2e-19 70.0 0.4 3e-19 69.5 0.4 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD23793.1 - 0.033 14.1 0.4 0.033 14.1 0.4 1.6 2 0 0 2 2 2 0 BclA C-terminal domain DAGAT PF03982.13 PVD23793.1 - 0.063 12.2 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Lectin_N PF03954.14 PVD23793.1 - 0.07 12.9 1.0 0.1 12.3 1.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TMEM192 PF14802.6 PVD23793.1 - 0.076 12.1 0.1 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 TMEM192 family SlyX PF04102.12 PVD23793.1 - 0.14 12.7 0.4 0.26 11.9 0.4 1.3 1 0 0 1 1 1 0 SlyX RhoGAP PF00620.27 PVD23795.1 - 5.7e-45 152.8 0.3 2.3e-44 150.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 PVD23795.1 - 0.0016 18.7 1.0 0.0081 16.4 0.2 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Urb2 PF10441.9 PVD23795.1 - 0.2 11.6 5.0 0.54 10.2 5.0 1.7 1 1 0 1 1 1 0 Urb2/Npa2 family MRG PF05712.13 PVD23795.1 - 0.49 9.7 3.8 1.3 8.3 3.5 1.9 1 1 0 1 1 1 0 MRG 2-oxoacid_dh PF00198.23 PVD23796.1 - 1.4e-66 224.2 0.0 5.3e-61 206.0 0.0 2.4 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PVD23796.1 - 3.2e-17 62.1 0.1 6.4e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PVD23796.1 - 7.2e-15 55.0 0.0 1.4e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain RCC1 PF00415.18 PVD23797.1 - 6.7e-46 154.7 9.8 7.1e-09 36.2 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 PVD23797.1 - 2.9e-41 141.6 0.2 2.4e-21 76.3 0.3 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23797.1 - 1.3e-28 100.0 0.4 2.3e-16 59.9 0.3 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase RCC1_2 PF13540.6 PVD23797.1 - 6.1e-21 73.7 36.8 6.8e-06 25.7 0.6 7.5 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat TauD PF02668.16 PVD23798.1 - 9.1e-23 81.4 0.1 4.1e-19 69.4 0.1 2.3 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DUF1768 PF08719.11 PVD23799.1 - 8.2e-55 185.4 0.1 9.8e-55 185.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Surfac_D-trimer PF09006.11 PVD23799.1 - 0.095 12.6 0.0 0.75 9.7 0.0 2.2 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF1768 PF08719.11 PVD23800.1 - 2.9e-35 121.9 0.7 3.3e-35 121.7 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) bZIP_2 PF07716.15 PVD23802.1 - 3.7e-09 36.5 14.9 5.7e-09 35.9 14.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD23802.1 - 8.1e-06 25.9 16.3 1.3e-05 25.2 16.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF4456 PF14644.6 PVD23802.1 - 0.011 15.5 1.0 0.018 14.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) bZIP_Maf PF03131.17 PVD23802.1 - 0.025 15.1 9.4 0.038 14.5 9.4 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Cnn_1N PF07989.11 PVD23802.1 - 0.027 14.6 5.0 0.048 13.8 5.0 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 PVD23802.1 - 0.25 11.6 3.9 0.49 10.6 3.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4407 PF14362.6 PVD23802.1 - 0.39 10.0 5.0 0.48 9.7 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 PVD23802.1 - 2 8.8 6.9 3.4 8.1 6.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.15 PVD23803.1 - 4.5e-16 58.7 11.6 6.4e-16 58.2 11.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD23803.1 - 2.1e-06 27.7 5.3 3.4e-06 27.1 5.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor TFIIF_alpha PF05793.12 PVD23804.1 - 4.8e-110 368.6 81.0 5.7e-109 365.1 81.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HiaBD2 PF15403.6 PVD23805.1 - 0.11 13.0 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) VWC PF00093.18 PVD23806.1 - 8.9e-12 45.1 14.7 1.4e-11 44.6 14.5 1.4 1 1 0 1 1 1 1 von Willebrand factor type C domain PSP94 PF05825.11 PVD23806.1 - 0.00046 20.7 6.2 0.00054 20.5 6.2 1.2 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) TILa PF12714.7 PVD23806.1 - 0.0025 17.7 11.9 0.0025 17.7 11.9 1.4 1 1 0 1 1 1 1 TILa domain Amnionless PF14828.6 PVD23806.1 - 0.033 13.0 12.2 0.036 12.9 12.2 1.1 1 0 0 1 1 1 0 Amnionless An_peroxidase PF03098.15 PVD23807.1 - 3.5e-151 504.4 0.0 2.1e-137 458.9 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase I-set PF07679.16 PVD23807.1 - 1.7e-52 175.5 0.0 2.6e-17 62.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD23807.1 - 1.4e-49 166.5 0.1 5.2e-16 59.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD23807.1 - 1.2e-33 115.2 0.0 5.8e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.6 PVD23807.1 - 3.1e-29 100.5 4.4 1.8e-16 59.6 0.2 2.7 1 1 1 2 2 2 2 Leucine rich repeat ig PF00047.25 PVD23807.1 - 2.4e-23 82.1 0.0 7.8e-07 29.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 PVD23807.1 - 7.9e-14 51.6 7.1 1.6e-05 25.2 0.4 5.1 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) V-set PF07686.17 PVD23807.1 - 8.1e-12 45.3 0.4 0.00057 20.0 0.0 5.4 3 3 2 5 5 5 2 Immunoglobulin V-set domain LRR_5 PF13306.6 PVD23807.1 - 3.1e-08 33.6 0.0 8.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) C2-set_2 PF08205.12 PVD23807.1 - 9.3e-08 32.0 0.0 0.078 13.1 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD23807.1 - 1.1e-07 32.1 0.0 0.074 13.5 0.0 3.5 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_9 PF14580.6 PVD23807.1 - 1.7e-07 31.0 0.8 0.0033 16.9 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Ig_C17orf99 PF17736.1 PVD23807.1 - 0.00025 21.0 0.0 2.8 8.0 0.0 4.1 3 1 0 3 3 3 1 C17orf99 Ig domain Ig_6 PF18452.1 PVD23807.1 - 0.00053 19.5 0.0 4.9 6.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain LRRCT PF01463.24 PVD23807.1 - 0.066 13.8 0.0 0.33 11.6 0.0 2.4 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 PVD23807.1 - 3.6 8.5 7.7 6e+02 1.7 0.0 5.9 6 0 0 6 6 5 0 Leucine Rich Repeat DEAD_2 PF06733.15 PVD23809.1 - 7.2e-53 178.8 3.0 1.6e-52 177.7 3.0 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 PVD23809.1 - 8.7e-52 175.7 0.1 4e-51 173.6 0.0 2.3 2 0 0 2 2 1 1 Helicase C-terminal domain ResIII PF04851.15 PVD23809.1 - 3.1e-06 27.3 0.0 0.00031 20.8 0.0 2.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD23809.1 - 3.5e-05 23.6 0.3 0.0025 17.6 0.3 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase BAR PF03114.18 PVD23809.1 - 0.0056 16.4 2.6 0.088 12.4 0.2 3.0 3 0 0 3 3 3 1 BAR domain SNF2_N PF00176.23 PVD23809.1 - 0.0065 15.2 0.1 0.042 12.6 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 PVD23809.1 - 0.0067 16.3 8.0 0.027 14.4 8.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD23809.1 - 0.0068 16.2 8.8 0.02 14.7 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_25 PF13481.6 PVD23809.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD23809.1 - 0.042 13.3 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein CCM2_C PF16545.5 PVD23809.1 - 0.057 14.0 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology zf-C3HC4_3 PF13920.6 PVD23809.1 - 0.36 10.7 14.8 0.025 14.4 9.4 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD23809.1 - 0.47 10.3 10.3 1.2 9.0 10.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PVD23809.1 - 0.67 10.1 7.3 2.2 8.5 7.3 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 PVD23809.1 - 4.1 7.8 12.1 14 6.1 12.1 2.0 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PVD23809.1 - 5.2 7.1 12.2 13 5.8 12.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Stathmin PF00836.19 PVD23810.1 - 1.5e-48 164.2 46.1 2.1e-34 118.4 16.6 3.1 1 1 2 3 3 3 3 Stathmin family Ribonuc_2-5A PF06479.12 PVD23810.1 - 0.0012 19.0 6.9 0.0012 19.0 6.9 2.2 1 1 1 2 2 2 1 Ribonuclease 2-5A RE_Eco29kI PF09517.10 PVD23810.1 - 0.066 12.8 11.8 5.3 6.6 0.3 3.4 1 1 2 3 3 3 0 Eco29kI restriction endonuclease Fib_alpha PF08702.10 PVD23810.1 - 0.13 12.5 27.9 0.31 11.2 10.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4279 PF14106.6 PVD23810.1 - 0.21 11.8 10.9 0.11 12.7 1.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) Apolipoprotein PF01442.18 PVD23810.1 - 0.3 10.9 37.0 0.58 10.0 37.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TSLP PF15216.6 PVD23810.1 - 0.99 9.7 9.8 0.38 11.0 5.7 2.3 1 1 1 2 2 2 0 Thymic stromal lymphopoietin MMPL PF03176.15 PVD23810.1 - 5.6 5.8 5.1 1.2 8.0 0.3 1.9 1 1 1 2 2 2 0 MMPL family NIL PF09383.10 PVD23810.1 - 8.8 6.3 6.7 16 5.5 0.2 2.8 3 0 0 3 3 3 0 NIL domain Tubulin PF00091.25 PVD23812.1 - 3.7e-55 187.2 0.0 4.4e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD23812.1 - 0.00028 20.6 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 PVD23813.1 - 1.6e-178 589.8 0.2 6.1e-54 183.2 0.0 5.0 2 2 2 4 4 4 4 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD23813.1 - 1.7e-20 73.4 0.0 0.001 18.8 0.0 4.3 4 0 0 4 4 4 4 Tubulin domain DUF1484 PF07363.11 PVD23813.1 - 3.9e-07 31.1 0.0 11 7.1 0.0 4.4 4 0 0 4 4 4 2 Protein of unknown function (DUF1484) Tubulin_2 PF13809.6 PVD23813.1 - 5.1e-06 25.9 2.2 6.1 5.9 0.1 4.3 4 0 0 4 4 4 4 Tubulin like Lipase_3 PF01764.25 PVD23813.1 - 0.00036 20.4 0.0 9.1 6.1 0.0 4.0 4 0 0 4 4 4 1 Lipase (class 3) Aminotran_MocR PF12897.7 PVD23813.1 - 0.13 11.0 0.0 49 2.5 0.0 3.0 3 0 0 3 3 3 0 Alanine-glyoxylate amino-transferase ComS PF17584.2 PVD23813.1 - 0.14 11.7 0.0 30 4.2 0.0 2.8 2 0 0 2 2 2 0 Bacillus competence protein S Phage_DNA_bind PF02303.17 PVD23813.1 - 0.14 12.4 0.1 80 3.6 0.0 3.2 3 0 0 3 3 3 0 Helix-destabilising protein zf-AN1 PF01428.16 PVD23813.1 - 0.23 11.7 0.7 1.7e+02 2.5 0.0 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger Tubulin PF00091.25 PVD23814.1 - 4.2e-111 369.8 0.0 1.2e-54 185.6 0.0 2.0 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD23814.1 - 7e-09 35.6 0.0 0.0019 17.9 0.0 2.3 2 0 0 2 2 2 2 Tubulin domain DUF1484 PF07363.11 PVD23814.1 - 0.0026 18.7 0.0 5.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1484) Tubulin_2 PF13809.6 PVD23814.1 - 0.056 12.6 0.9 5.3 6.1 0.1 2.1 2 0 0 2 2 2 0 Tubulin like Phage_DNA_bind PF02303.17 PVD23814.1 - 0.075 13.3 0.0 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Helix-destabilising protein Tubulin PF00091.25 PVD23815.1 - 7.7e-55 186.1 0.0 9.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD23815.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Lig_chan-Glu_bd PF10613.9 PVD23817.1 - 2.8e-21 75.9 0.1 9.7e-21 74.1 0.1 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD23817.1 - 3e-18 66.1 0.5 5.4e-18 65.3 0.5 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD23817.1 - 5.9e-16 58.6 0.0 9.2e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Apt1 PF10351.9 PVD23818.1 - 0.068 12.0 8.6 0.11 11.3 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain STAC2_u1 PF16664.5 PVD23818.1 - 9 6.8 11.5 3.4 8.1 6.2 2.3 2 1 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Lectin_C PF00059.21 PVD23821.1 - 3.1e-17 63.3 15.0 2.5e-07 31.4 0.2 5.1 5 1 0 5 5 5 3 Lectin C-type domain UL45 PF05473.12 PVD23821.1 - 8.1e-10 38.7 12.2 9e-05 22.2 2.9 3.2 3 0 0 3 3 3 3 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 PVD23821.1 - 0.0001 21.6 5.3 0.083 12.2 0.1 3.5 3 1 1 4 4 4 2 Chordopoxvirus A33R protein Xlink PF00193.17 PVD23821.1 - 0.0024 18.2 4.1 5.9 7.4 0.3 4.2 3 1 1 4 4 4 2 Extracellular link domain BSD PF03909.17 PVD23823.1 - 3.8e-16 58.8 0.8 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 BSD domain XK-related PF09815.9 PVD23824.1 - 1.5e-46 159.0 9.2 1.4e-29 103.3 2.7 2.1 1 1 1 2 2 2 2 XK-related protein RrnaAD PF00398.20 PVD23825.1 - 7.1e-19 67.9 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PVD23825.1 - 0.05 14.3 0.0 0.29 11.9 0.0 2.1 2 1 2 4 4 4 0 Methyltransferase domain Methyltransf_PK PF05891.12 PVD23825.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Ank_2 PF12796.7 PVD23826.1 - 1.7e-116 381.0 35.2 1.4e-14 54.4 0.2 12.1 2 1 9 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.30 PVD23826.1 - 1e-92 300.8 36.2 4.6e-08 33.2 0.3 21.5 21 0 0 21 21 21 19 Ankyrin repeat Ank_4 PF13637.6 PVD23826.1 - 8e-92 300.5 22.5 7.7e-17 61.4 0.2 16.3 7 5 9 17 17 17 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD23826.1 - 6.5e-87 284.5 27.8 2.2e-11 43.8 0.0 18.5 8 5 10 18 18 18 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD23826.1 - 5.9e-85 269.0 21.6 4.7e-06 26.5 0.1 22.6 22 0 0 22 22 22 17 Ankyrin repeat Ion_trans PF00520.31 PVD23826.1 - 3.9e-09 36.1 22.9 1.2e-08 34.4 22.8 1.8 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PVD23826.1 - 0.69 8.5 15.1 5.8 5.5 15.1 2.1 1 1 0 1 1 1 0 Polycystin cation channel IPK PF03770.16 PVD23827.1 - 2.5e-55 187.4 0.0 3.5e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase IPK PF03770.16 PVD23829.1 - 1.5e-51 175.1 0.0 5.1e-51 173.4 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase SNARE PF05739.19 PVD23829.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 SNARE domain 4HBT PF03061.22 PVD23830.1 - 1.4e-16 60.6 0.4 2.1e-16 60.0 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 PVD23830.1 - 2.2e-05 24.8 0.0 2.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 PVD23830.1 - 0.0006 20.0 0.0 0.00079 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) VirE2 PF07229.12 PVD23830.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 VirE2 Galactosyl_T PF01762.21 PVD23831.1 - 1.9e-11 44.1 0.1 4.5e-11 42.9 0.0 1.6 2 1 0 2 2 2 1 Galactosyltransferase HECT PF00632.25 PVD23832.1 - 7.9e-50 170.1 0.0 1.5e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 PVD23832.1 - 9e-11 41.7 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 PVD23832.1 - 5.7e-07 29.7 0.2 2e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain 7tm_1 PF00001.21 PVD23833.1 - 1.7e-24 86.6 22.0 1.8e-23 83.2 22.0 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD23833.1 - 5.2e-07 29.5 13.6 1.1e-06 28.5 13.6 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD23833.1 - 0.00015 21.2 3.6 0.00015 21.2 3.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2477 PF10631.9 PVD23833.1 - 0.013 16.2 3.6 0.086 13.5 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) Peptidase_M28 PF04389.17 PVD23834.1 - 3.2e-41 141.2 0.0 4.9e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 PVD23834.1 - 0.00039 20.2 0.0 0.00048 19.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1854 PF08909.11 PVD23834.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) zf-RanBP PF00641.18 PVD23835.1 - 2.3e-13 49.2 19.2 1.5e-07 30.6 7.4 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 PVD23835.1 - 0.00018 21.3 3.4 0.21 11.5 0.7 2.4 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF572 PF04502.13 PVD23835.1 - 0.18 11.4 19.7 0.33 10.5 19.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1387 PF07139.11 PVD23835.1 - 0.66 9.6 28.8 1 9.0 28.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DZR PF12773.7 PVD23835.1 - 1.3 9.1 9.3 9.2 6.4 1.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon Nop14 PF04147.12 PVD23835.1 - 2.1 6.5 27.2 3.2 5.9 27.2 1.4 1 0 0 1 1 1 0 Nop14-like family FG-GAP PF01839.23 PVD23836.1 - 2.4e-30 104.3 29.0 4.8e-08 33.0 2.4 5.2 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 PVD23836.1 - 1.2e-14 54.6 11.7 1.8e-08 34.8 0.6 4.7 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Zn_dep_PLPC PF00882.18 PVD23836.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C TcdB_toxin_midN PF12256.8 PVD23836.1 - 0.0029 17.0 2.2 0.088 12.2 0.0 3.5 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region PNK3P PF08645.11 PVD23837.1 - 2.5e-56 189.8 0.0 4.6e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 PVD23837.1 - 1.5e-21 77.1 0.0 4.8e-12 46.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain 6PF2K PF01591.18 PVD23837.1 - 0.00017 21.0 0.0 0.032 13.5 0.0 2.4 1 1 1 2 2 2 2 6-phosphofructo-2-kinase KTI12 PF08433.10 PVD23837.1 - 0.00063 19.3 0.0 0.17 11.3 0.1 2.2 1 1 0 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 PVD23837.1 - 0.0069 15.7 0.0 0.75 9.0 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin AAA_22 PF13401.6 PVD23837.1 - 0.059 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nucleic_acid_bd PF13820.6 PVD23838.1 - 1.3e-25 90.0 0.3 3.3e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 Putative nucleic acid-binding region Annexin PF00191.20 PVD23840.1 - 2.4e-66 219.7 10.4 6.4e-24 83.8 0.2 5.0 4 1 0 4 4 4 4 Annexin MetOD1 PF18546.1 PVD23840.1 - 0.029 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Metanogen output domain 1 ubiquitin PF00240.23 PVD23841.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin family fn3 PF00041.21 PVD23842.1 - 2e-11 44.0 4.3 9.2e-05 22.7 0.7 4.5 4 0 0 4 4 4 2 Fibronectin type III domain ig PF00047.25 PVD23842.1 - 0.01 16.0 0.0 0.061 13.5 0.0 2.4 1 0 0 1 1 1 0 Immunoglobulin domain Cornifin PF02389.15 PVD23843.1 - 0.21 11.8 0.0 0.29 11.3 0.0 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family TSP_3 PF02412.18 PVD23843.1 - 2.9 7.6 10.1 1.3 8.7 5.1 2.8 2 1 0 2 2 2 0 Thrombospondin type 3 repeat Big_4 PF07532.11 PVD23844.1 - 0.03 14.1 0.1 0.95 9.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Big_3_5 PF16640.5 PVD23845.1 - 0.0046 17.1 0.0 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) fn3 PF00041.21 PVD23847.1 - 1.7e-13 50.7 15.9 5e-06 26.8 1.0 4.9 5 0 0 5 5 5 2 Fibronectin type III domain IL6Ra-bind PF09240.10 PVD23847.1 - 0.039 14.4 5.8 0.063 13.7 2.0 2.9 2 1 1 3 3 3 0 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 PVD23847.1 - 1.4 9.1 5.1 0.67 10.2 0.3 2.7 3 0 0 3 3 3 0 Erythropoietin receptor, ligand binding fn3 PF00041.21 PVD23851.1 - 5.2e-09 36.3 7.7 9.9e-09 35.4 0.1 4.4 5 0 0 5 5 5 1 Fibronectin type III domain GPI-anchored PF10342.9 PVD23851.1 - 0.0086 16.8 1.3 0.41 11.4 0.0 3.6 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Interfer-bind PF09294.10 PVD23851.1 - 0.014 15.7 1.6 0.26 11.6 0.0 2.9 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 PVD23851.1 - 0.037 14.6 0.1 0.037 14.6 0.1 2.7 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 PVD23851.1 - 0.19 12.3 0.6 13 6.4 0.0 2.8 2 1 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PAP2 PF01569.21 PVD23852.1 - 1.7e-10 40.8 6.4 5e-10 39.3 6.4 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF3087 PF11286.8 PVD23852.1 - 0.57 9.6 1.8 1.1 8.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) fn3 PF00041.21 PVD23854.1 - 9.7e-09 35.5 0.2 0.24 11.8 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.10 PVD23854.1 - 0.0047 17.2 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III CD34_antigen PF06365.12 PVD23854.1 - 0.049 13.2 0.1 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family fn3 PF00041.21 PVD23855.1 - 3.9e-07 30.3 10.1 0.0028 17.9 0.0 5.5 6 0 0 6 6 6 3 Fibronectin type III domain CARDB PF07705.11 PVD23855.1 - 0.24 11.7 3.9 72 3.7 0.1 3.7 3 0 0 3 3 3 0 CARDB fn3 PF00041.21 PVD23856.1 - 1.1e-10 41.7 3.5 0.047 14.0 0.0 5.4 5 0 0 5 5 5 3 Fibronectin type III domain Interfer-bind PF09294.10 PVD23856.1 - 0.012 15.9 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III ELO PF01151.18 PVD23857.1 - 7.7e-20 71.5 2.8 1e-19 71.1 2.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5578 PF17741.1 PVD23858.1 - 3.1e-84 282.6 0.5 4.7e-84 282.0 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 PVD23858.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Arm PF00514.23 PVD23858.1 - 0.0085 16.1 3.2 0.27 11.4 0.1 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD23858.1 - 0.0097 16.3 0.5 0.5 10.8 0.0 3.4 2 2 1 3 3 3 1 HEAT repeats DUF829 PF05705.14 PVD23859.1 - 5.5e-55 186.9 0.0 6.4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 PVD23859.1 - 0.0057 16.2 0.1 0.044 13.3 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PVD23859.1 - 0.078 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DSPc PF00782.20 PVD23860.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD23860.1 - 2e-08 34.1 0.1 3.7e-08 33.2 0.1 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PVD23860.1 - 4.2e-07 30.2 0.0 6.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 PVD23860.1 - 0.00026 20.6 0.0 0.0025 17.4 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PVD23860.1 - 0.00034 20.7 0.4 0.00053 20.0 0.4 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Glyco_trans_4_2 PF13477.6 PVD23860.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like DSPn PF14671.6 PVD23860.1 - 0.17 12.4 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half EF-hand_7 PF13499.6 PVD23861.1 - 3.2e-25 88.4 2.6 2.2e-15 56.9 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD23861.1 - 1.2e-23 80.8 7.4 4.2e-07 29.1 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PVD23861.1 - 2.9e-20 70.4 2.3 3.4e-06 26.6 0.1 4.9 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 PVD23861.1 - 2.1e-19 68.1 5.0 2.4e-05 23.6 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD23861.1 - 3.4e-17 62.0 4.7 4.7e-07 29.6 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD23861.1 - 0.00011 22.5 0.4 0.12 12.7 0.0 3.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD23861.1 - 0.017 15.1 0.9 4.3 7.3 0.0 3.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF1822 PF08852.11 PVD23861.1 - 0.086 11.9 0.0 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Dockerin_1 PF00404.18 PVD23861.1 - 0.13 12.5 1.0 42 4.5 0.0 3.4 3 1 0 3 3 3 0 Dockerin type I domain EF-hand_10 PF14788.6 PVD23861.1 - 0.27 11.1 0.7 19 5.2 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 PVD23864.1 - 1.7e-25 89.2 4.1 2.4e-15 56.7 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD23864.1 - 1.3e-21 74.5 9.3 1.7e-06 27.1 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD23864.1 - 4.4e-21 73.0 4.4 1.2e-05 24.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD23864.1 - 2.9e-16 58.1 8.8 2e-05 23.8 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 PVD23864.1 - 5.9e-15 54.9 7.8 1.3e-07 31.4 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD23864.1 - 9.9e-08 32.3 1.8 0.19 12.1 0.0 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD23864.1 - 1.4e-07 31.4 0.9 0.00085 19.2 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PVD23864.1 - 0.00047 20.0 1.6 0.12 12.2 0.0 3.5 3 1 1 4 4 4 1 EF hand DAG_kinase_N PF14513.6 PVD23864.1 - 0.0059 16.8 0.2 0.0064 16.7 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus LPD28 PF18843.1 PVD23864.1 - 0.014 15.0 0.2 0.065 12.9 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 28 NADPH_Ox PF08414.10 PVD23864.1 - 0.1 12.9 0.7 1.1 9.6 0.3 2.3 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase EF-hand_14 PF17959.1 PVD23864.1 - 0.14 12.5 1.1 2.6 8.5 0.1 2.9 3 1 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 PVD23864.1 - 0.46 10.7 4.9 0.84 9.9 0.3 2.5 1 1 1 2 2 2 0 Dockerin type I domain SGL PF08450.12 PVD23866.1 - 1.3e-76 257.4 0.7 1.5e-76 257.2 0.7 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PVD23866.1 - 0.0034 17.4 0.8 4.6 7.8 0.1 3.0 2 0 0 2 2 2 2 Two component regulator propeller Phytase-like PF13449.6 PVD23866.1 - 0.11 12.4 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 Esterase-like activity of phytase SGL PF08450.12 PVD23867.1 - 2.6e-68 230.3 1.1 3e-68 230.0 1.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PVD23867.1 - 0.0061 16.6 0.9 3.7 8.1 0.1 3.7 3 1 0 3 3 3 2 Two component regulator propeller SGL PF08450.12 PVD23868.1 - 6e-73 245.5 2.4 7.8e-73 245.1 2.4 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PVD23868.1 - 0.0015 18.5 1.3 1.6 9.2 0.0 3.2 3 0 0 3 3 3 2 Two component regulator propeller NHL PF01436.21 PVD23868.1 - 0.082 13.0 0.0 0.55 10.4 0.0 2.5 3 0 0 3 3 3 0 NHL repeat SGL PF08450.12 PVD23871.1 - 1.2e-60 205.2 0.3 1.7e-60 204.6 0.3 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PVD23871.1 - 0.19 12.1 0.7 76 4.1 0.0 3.8 4 0 0 4 4 4 0 Two component regulator propeller SGL PF08450.12 PVD23872.1 - 1.2e-112 375.4 5.9 3.8e-79 265.7 0.3 4.3 2 1 2 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region zf-H2C2_5 PF13909.6 PVD23872.1 - 0.002 17.8 6.0 0.073 12.8 0.1 3.7 3 0 0 3 3 3 1 C2H2-type zinc-finger domain NHL PF01436.21 PVD23872.1 - 0.031 14.3 0.2 10 6.4 0.0 3.1 2 0 0 2 2 2 0 NHL repeat Reg_prop PF07494.11 PVD23872.1 - 0.55 10.6 1.6 39 5.0 0.1 3.9 3 0 0 3 3 3 0 Two component regulator propeller PetG PF02529.15 PVD23873.1 - 2.3 8.1 3.5 4.3 7.3 3.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Methyltransf_15 PF09445.10 PVD23874.1 - 3.2e-39 134.1 0.0 6.7e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 PVD23874.1 - 9.4e-07 28.7 0.0 3.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD23874.1 - 1.5e-06 28.8 0.0 7.5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 PVD23874.1 - 8.3e-06 25.6 0.3 5e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 PVD23874.1 - 2.2e-05 24.3 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 PVD23874.1 - 0.0023 18.6 0.1 0.013 16.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PVD23874.1 - 0.0033 17.4 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD23874.1 - 0.016 14.8 0.0 0.066 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DNA_ligase_A_N PF04675.14 PVD23875.1 - 1.2e-39 136.4 0.4 1.9e-39 135.7 0.4 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 PVD23875.1 - 4.6e-23 81.9 0.0 8.7e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 PVD23875.1 - 1.5e-19 70.4 0.0 4e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.8 PVD23875.1 - 5.1e-14 52.1 1.4 1.2e-13 50.9 1.4 1.7 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.26 PVD23875.1 - 7e-06 26.3 0.0 0.00097 19.5 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD23875.1 - 2.8e-05 24.4 0.0 0.0041 17.5 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 PVD23875.1 - 0.0043 17.4 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 RNA ligase DUF664 PF04978.12 PVD23875.1 - 0.043 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF664) mRNA_cap_enzyme PF01331.19 PVD23875.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain NUDIX PF00293.28 PVD23876.1 - 3.8e-13 49.6 1.0 5.5e-13 49.1 1.0 1.3 1 0 0 1 1 1 1 NUDIX domain PQ-loop PF04193.14 PVD23877.1 - 7.6e-37 124.9 15.1 9.4e-20 70.2 2.3 2.7 2 0 0 2 2 2 2 PQ loop repeat zf-C2H2_2 PF12756.7 PVD23878.1 - 0.00043 20.6 0.8 0.0017 18.7 0.8 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PVD23878.1 - 0.012 16.0 2.0 0.015 15.7 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD23878.1 - 0.014 16.2 0.2 0.057 14.3 0.2 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Hid1 PF12722.7 PVD23878.1 - 6 4.9 8.4 7.9 4.5 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-C2H2_jaz PF12171.8 PVD23880.1 - 5.7e-09 36.0 3.6 1.7e-08 34.6 3.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DnaJ PF00226.31 PVD23880.1 - 1.6e-06 28.1 0.1 4.6e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_2 PF12756.7 PVD23880.1 - 0.00017 21.8 0.1 0.00043 20.6 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PVD23880.1 - 0.0002 21.6 3.4 0.0002 21.6 3.4 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PVD23880.1 - 0.16 12.9 0.3 0.16 12.9 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3258 PF11646.8 PVD23880.1 - 0.83 9.8 4.1 3.8 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3258 RGS PF00615.19 PVD23881.1 - 5.2e-20 71.9 8.4 1.4e-09 38.2 0.1 5.5 5 1 0 6 6 6 2 Regulator of G protein signaling domain STN1_2 PF09170.10 PVD23881.1 - 0.66 10.2 4.1 5.4 7.2 0.2 3.0 3 0 0 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 NCKAP5 PF15246.6 PVD23881.1 - 0.72 9.4 13.5 0.018 14.6 6.6 1.8 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Hydrolase PF00702.26 PVD23891.1 - 3.1e-06 27.6 0.0 4.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 PVD23892.1 - 1.4e-39 135.5 3.0 9.5e-34 116.6 0.1 2.0 1 1 1 2 2 2 2 Ferlin C-terminus Wzz PF02706.15 PVD23892.1 - 0.17 12.2 4.3 0.28 11.5 4.3 1.2 1 0 0 1 1 1 0 Chain length determinant protein Synaptobrevin PF00957.21 PVD23892.1 - 0.48 10.2 5.6 0.73 9.7 5.6 1.2 1 0 0 1 1 1 0 Synaptobrevin C2 PF00168.30 PVD23896.1 - 5.7e-60 200.0 0.6 1.4e-18 67.0 0.0 6.4 6 0 0 6 6 6 6 C2 domain FerI PF08151.12 PVD23896.1 - 7.6e-11 41.9 1.8 7e-10 38.9 1.8 2.4 1 1 0 1 1 1 1 FerI (NUC094) domain FerB PF08150.12 PVD23896.1 - 0.00019 21.9 0.2 0.00068 20.2 0.2 2.0 1 0 0 1 1 1 1 FerB (NUC096) domain Tfb5 PF06331.12 PVD23898.1 - 0.049 13.6 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 PITH PF06201.13 PVD23899.1 - 1.5e-36 125.9 0.0 2.5e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 PITH domain HMG_box PF00505.19 PVD23900.1 - 1.3e-24 86.4 2.9 3.2e-24 85.1 2.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD23900.1 - 3.9e-10 40.2 1.8 7.7e-10 39.2 1.8 1.5 1 0 0 1 1 1 1 HMG-box domain FAD-SLDH PF12318.8 PVD23901.1 - 0.093 12.8 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Porph_ging PF09697.10 PVD23901.1 - 0.12 12.9 0.6 0.26 11.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) SVWC PF15430.6 PVD23902.1 - 2.1e-06 27.9 7.2 5.3e-06 26.6 7.2 1.7 1 0 0 1 1 1 1 Single domain von Willebrand factor type C Ntox35 PF15534.6 PVD23902.1 - 0.092 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 35 PHD_3 PF13922.6 PVD23903.1 - 1.4e-18 67.0 11.7 1.4e-18 67.0 11.7 4.2 5 0 0 5 5 5 1 PHD domain of transcriptional enhancer, Asx ASXH PF13919.6 PVD23903.1 - 1.6e-14 54.1 0.9 1.6e-14 54.1 0.9 1.9 2 0 0 2 2 2 1 Asx homology domain PHD PF00628.29 PVD23903.1 - 0.95 9.4 10.3 1.9 8.4 10.3 1.4 1 0 0 1 1 1 0 PHD-finger TGF_beta PF00019.20 PVD23905.1 - 7.4e-12 46.2 1.5 2.9e-11 44.3 0.0 2.7 4 0 0 4 4 4 1 Transforming growth factor beta like domain DAN PF03045.15 PVD23905.1 - 0.00039 20.4 0.5 0.0012 18.9 0.1 2.1 2 1 0 2 2 2 1 DAN domain Galactosyl_T PF01762.21 PVD23906.1 - 1.6e-44 152.1 0.0 2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 PVD23907.1 - 7.7e-46 156.4 0.1 1.1e-45 155.9 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD23907.1 - 0.13 11.6 0.3 0.66 9.4 0.3 2.0 1 1 0 1 1 1 0 Fringe-like DAP_epimerase PF01678.19 PVD23907.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase DUF3807 PF12720.7 PVD23908.1 - 0.26 11.5 18.6 0.31 11.3 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Apt1 PF10351.9 PVD23908.1 - 0.39 9.5 20.9 0.45 9.3 20.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Roughex PF06020.11 PVD23908.1 - 0.5 9.4 12.5 0.56 9.2 12.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4667 PF15700.5 PVD23908.1 - 0.65 10.1 22.5 0.72 9.9 22.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Asp-B-Hydro_N PF05279.11 PVD23908.1 - 0.69 9.9 22.0 0.77 9.8 22.0 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 PVD23908.1 - 1.6 6.9 20.9 1.7 6.8 20.9 1.0 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 PVD23908.1 - 4.8 6.4 11.0 5.7 6.1 11.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF4674 PF15719.5 PVD23908.1 - 5.1 7.1 25.4 4.6 7.2 17.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) Presenilin PF01080.17 PVD23908.1 - 6.3 5.4 21.0 6.9 5.3 21.0 1.1 1 0 0 1 1 1 0 Presenilin MMM1 PF10296.9 PVD23908.1 - 9.7 5.1 15.3 24 3.8 15.3 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Galactosyl_T PF01762.21 PVD23909.1 - 1.3e-46 158.9 0.1 1.3e-46 158.9 0.1 1.9 2 1 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 PVD23909.1 - 0.001 18.6 0.2 0.0026 17.2 0.2 1.7 1 1 0 1 1 1 1 Fringe-like Mem_trans PF03547.18 PVD23909.1 - 0.019 13.4 0.5 0.02 13.3 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Apt1 PF10351.9 PVD23909.1 - 0.052 12.4 23.3 0.078 11.8 23.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glycos_transf_2 PF00535.26 PVD23909.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Macoilin PF09726.9 PVD23909.1 - 0.14 10.7 24.8 0.17 10.4 24.8 1.1 1 0 0 1 1 1 0 Macoilin family PAN_1 PF00024.26 PVD23910.1 - 9.6e-62 204.9 87.2 2.5e-09 37.0 3.1 9.4 9 0 0 9 9 9 9 PAN domain Ependymin PF00811.18 PVD23910.1 - 0.0022 18.2 1.2 0.086 13.1 0.0 3.8 3 0 0 3 3 3 1 Ependymin PAN_4 PF14295.6 PVD23910.1 - 0.0042 16.9 73.9 0.11 12.4 1.0 9.9 9 0 0 9 9 9 8 PAN domain Sgf11_N PF18519.1 PVD23910.1 - 2.4 7.8 4.9 11 5.6 0.1 3.4 3 0 0 3 3 3 0 SAGA-associated factor 11 N-terminal domain Neuroparsin PF07327.11 PVD23910.1 - 4 7.9 10.0 0.98 9.9 0.3 4.1 3 0 0 3 3 3 0 Neuroparsin 7tm_1 PF00001.21 PVD23912.1 - 1.7e-54 184.9 20.6 2.1e-54 184.6 20.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD23912.1 - 1.8e-06 27.5 20.4 8.5e-06 25.3 20.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD23912.1 - 2.2e-06 27.2 24.0 0.00083 18.7 3.1 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD23912.1 - 7.9e-05 22.4 16.2 7.9e-05 22.4 16.2 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD23912.1 - 0.063 13.0 21.3 0.035 13.8 11.3 2.4 2 1 0 2 2 2 0 Olfactory receptor RWD PF05773.22 PVD23913.1 - 1.6e-11 44.5 0.0 3.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF61 PF01886.16 PVD23913.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF61 DUF1115 PF06544.12 PVD23913.1 - 0.051 13.7 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) 7tm_1 PF00001.21 PVD23914.1 - 5.1e-54 183.4 15.7 6.8e-54 182.9 15.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD23914.1 - 1.6e-09 37.9 12.1 3.5e-09 36.8 12.1 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD23914.1 - 2.3e-07 30.7 8.4 2.3e-07 30.7 8.4 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD23914.1 - 0.0018 17.6 21.7 0.059 12.7 21.7 3.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4059 PF13268.6 PVD23914.1 - 2.3 8.7 10.7 0.33 11.4 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) SKG6 PF08693.10 PVD23915.1 - 0.81 9.1 4.7 1.5 8.3 4.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sulfotransfer_1 PF00685.27 PVD23916.1 - 2.1e-14 53.6 0.3 2.6e-14 53.3 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD23916.1 - 9.4e-11 42.5 0.1 1.4e-10 41.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD23917.1 - 5.5e-31 108.0 0.0 7.1e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD23917.1 - 3.9e-15 56.8 0.1 4.4e-09 37.0 0.2 2.2 1 1 1 2 2 2 2 Sulfotransferase family DUF1748 PF08520.10 PVD23918.1 - 0.055 13.4 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Ribosomal_L7Ae PF01248.26 PVD23919.1 - 6.4e-15 54.7 0.5 1.9e-11 43.5 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TyrRSs_C PF16714.5 PVD23919.1 - 0.034 14.0 0.1 0.41 10.5 0.0 2.0 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain R3H-assoc PF13902.6 PVD23920.1 - 1.1e-18 67.9 1.1 2.3e-18 66.9 1.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 PVD23920.1 - 1e-09 38.2 0.3 2.2e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 R3H domain FA_hydroxylase PF04116.13 PVD23921.1 - 4.1e-09 36.9 17.3 4.1e-09 36.9 17.3 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 7tm_1 PF00001.21 PVD23922.1 - 4.1e-18 65.6 10.3 5.1e-18 65.3 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD23922.1 - 0.00013 21.4 8.0 0.00034 20.0 8.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1129 PF06570.11 PVD23922.1 - 4.6 6.7 9.8 3.4 7.1 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Wzz PF02706.15 PVD23922.1 - 6.1 7.2 6.7 2 8.8 0.1 2.5 1 1 1 2 2 2 0 Chain length determinant protein NDUFA12 PF05071.16 PVD23926.1 - 6.7e-13 49.3 2.6 1.1e-12 48.6 2.6 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Adaptin_N PF01602.20 PVD23927.1 - 7.3e-121 404.3 12.1 6.7e-98 328.5 6.5 2.1 1 1 1 2 2 2 2 Adaptin N terminal region AP3D1 PF06375.11 PVD23927.1 - 2.2e-35 122.2 44.9 2e-32 112.7 9.2 3.5 3 0 0 3 3 3 3 AP-3 complex subunit delta-1 Cnd1 PF12717.7 PVD23927.1 - 3.4e-13 50.0 2.3 5.7e-09 36.2 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PVD23927.1 - 3.2e-06 26.9 0.2 0.73 10.3 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 PVD23927.1 - 1.4e-05 25.4 0.6 0.061 13.7 0.0 4.1 4 1 1 5 5 5 2 HEAT repeats SR-25 PF10500.9 PVD23927.1 - 0.00055 19.6 44.0 0.066 12.8 11.2 3.5 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein RTP1_C1 PF10363.9 PVD23927.1 - 0.00085 19.5 3.7 1.3 9.2 0.9 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 PVD23927.1 - 0.0018 18.6 0.1 0.2 12.1 0.3 3.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 PVD23927.1 - 0.026 15.1 0.4 0.78 10.4 0.1 3.3 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 PVD23927.1 - 0.25 11.5 0.6 96 3.2 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat POP1 PF06978.11 PVD23928.1 - 2.4e-38 132.2 16.0 8.5e-22 78.2 3.7 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 PVD23928.1 - 5.1e-29 100.5 0.7 9.5e-28 96.4 0.0 3.0 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T PF01571.21 PVD23928.1 - 0.01 15.3 0.0 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 Aminomethyltransferase folate-binding domain Tagatose_6_P_K PF08013.11 PVD23928.1 - 0.14 10.8 0.3 0.34 9.6 0.1 1.6 2 0 0 2 2 2 0 Tagatose 6 phosphate kinase Ribonuc_L-PSP PF01042.21 PVD23929.1 - 3e-40 137.0 1.2 3.5e-40 136.8 1.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pilus_CpaD PF09476.10 PVD23929.1 - 0.089 12.5 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Corona_6B_7B PF03262.13 PVD23929.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus 6B/7B protein SAM_2 PF07647.17 PVD23930.1 - 2.5e-10 40.3 0.2 4e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD23930.1 - 1.3e-07 32.0 0.4 1.9e-07 31.4 0.4 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 PVD23931.1 - 6.3e-17 61.8 0.8 8.9e-17 61.3 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD23931.1 - 9.6e-08 31.6 0.1 1.6e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 PVD23931.1 - 0.0023 17.3 0.2 0.0064 15.8 0.1 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 PVD23931.1 - 0.024 14.6 0.0 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD23931.1 - 0.068 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Laminin_EGF PF00053.24 PVD23933.1 - 4.8e-112 366.0 328.8 9.3e-10 38.5 11.9 20.3 18 4 1 19 19 19 16 Laminin EGF domain Laminin_G_2 PF02210.24 PVD23933.1 - 7e-68 227.0 4.6 2e-18 67.2 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 PVD23933.1 - 1.2e-65 219.6 2.0 1.5e-16 60.8 0.0 6.0 4 2 2 6 6 6 5 Laminin G domain Laminin_B PF00052.18 PVD23933.1 - 5.8e-57 191.4 0.0 1.9e-33 115.2 0.1 2.5 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_N PF00055.17 PVD23933.1 - 2.3e-48 164.8 0.0 3.8e-28 98.7 0.0 4.6 5 0 0 5 5 5 2 Laminin N-terminal (Domain VI) Laminin_G_3 PF13385.6 PVD23933.1 - 1e-17 64.7 3.0 0.0064 16.6 0.1 5.4 5 0 0 5 5 5 4 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 PVD23933.1 - 5.5e-05 23.2 1.0 5.5e-05 23.2 1.0 5.0 1 1 4 5 5 5 2 Laminin Domain II DUF1664 PF07889.12 PVD23933.1 - 0.99 9.5 19.7 0.018 15.0 2.7 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SesA PF17107.5 PVD23933.1 - 2.4 8.3 14.6 1.9 8.7 1.5 4.1 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4164 PF13747.6 PVD23933.1 - 6.1 7.2 22.2 0.0072 16.6 5.6 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF676 PF05057.14 PVD23934.1 - 2.8e-56 190.5 0.0 5.1e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 PVD23934.1 - 1.2e-17 64.2 0.1 4.2e-17 62.4 0.1 2.1 1 0 0 1 1 1 1 Protein FAM135 Palm_thioest PF02089.15 PVD23934.1 - 2.7e-07 30.7 0.0 6.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 PVD23934.1 - 1.2e-05 25.2 0.3 4.1e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Tugs PF17840.1 PVD23934.1 - 0.045 13.9 0.3 0.23 11.7 0.3 2.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain LCAT PF02450.15 PVD23934.1 - 0.13 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 PVD23934.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Mic1 PF07035.12 PVD23935.1 - 5.7e-69 230.8 2.2 1.5e-68 229.4 2.2 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Frigida PF07899.11 PVD23935.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Frigida-like protein ELO PF01151.18 PVD23936.1 - 1.2e-49 169.1 13.8 1.4e-49 168.9 13.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5090 PF17009.5 PVD23936.1 - 0.14 12.1 2.2 0.14 12.1 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) TTL PF03133.15 PVD23937.1 - 6.5e-82 275.0 1.8 8e-82 274.7 0.5 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD23937.1 - 4.9e-09 35.8 1.4 0.00013 21.4 0.0 3.6 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD23937.1 - 4.1e-05 23.0 0.0 0.025 13.9 0.0 2.9 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 PVD23937.1 - 0.00046 20.3 0.0 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 PVD23937.1 - 0.0044 16.6 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Thiolase_N PF00108.23 PVD23938.1 - 4.6e-17 62.2 0.3 3.7e-14 52.7 0.0 3.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD23938.1 - 8.3e-11 41.6 0.1 1.5e-09 37.6 0.1 2.8 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PVD23938.1 - 0.0002 21.0 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 PVD23938.1 - 0.0022 17.8 0.1 0.027 14.3 0.0 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DSBA PF01323.20 PVD23938.1 - 0.0045 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SpoVAD PF07451.11 PVD23938.1 - 0.01 14.5 0.0 0.045 12.5 0.0 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 PVD23938.1 - 0.015 15.4 1.4 9.1 6.3 0.0 3.7 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 PVD23939.1 - 1.1e-33 116.4 0.0 1.7e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD23939.1 - 1.6e-28 99.8 0.0 2.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 PVD23939.1 - 8e-25 87.3 0.6 1.9e-24 86.1 0.5 1.7 2 0 0 2 2 2 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 PVD23939.1 - 5.2e-07 30.0 0.0 9.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal KR PF08659.10 PVD23939.1 - 3.6e-06 27.0 0.1 6.7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 KR domain SCP2_2 PF13530.6 PVD23939.1 - 0.0007 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain THF_DHG_CYH_C PF02882.19 PVD23939.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GWT1 PF06423.12 PVD23941.1 - 1.3e-37 129.2 2.1 1.3e-37 129.2 2.1 3.0 4 0 0 4 4 4 1 GWT1 DNA_repr_REX1B PF14966.6 PVD23942.1 - 5.6e-16 59.0 3.2 7.9e-16 58.5 2.1 1.7 2 0 0 2 2 2 1 DNA repair REX1-B Snapin_Pallidin PF14712.6 PVD23942.1 - 0.015 15.7 0.5 0.03 14.7 0.3 1.6 1 1 0 1 1 1 0 Snapin/Pallidin MRP-L28 PF09812.9 PVD23942.1 - 0.046 13.9 0.3 0.056 13.6 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 NAC PF01849.18 PVD23943.1 - 2.3e-25 88.3 0.2 4.5e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 NAC domain HAMP PF00672.25 PVD23943.1 - 0.052 13.9 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 HAMP domain dCache_1 PF02743.18 PVD23943.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Cache domain SHNi-TPR PF10516.9 PVD23944.1 - 3.4e-14 52.0 8.0 5.5e-12 44.9 1.5 3.8 4 0 0 4 4 4 2 SHNi-TPR TPR_1 PF00515.28 PVD23944.1 - 1.3e-06 27.9 3.5 0.022 14.6 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD23944.1 - 4.3e-06 26.5 8.1 0.0007 19.6 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD23944.1 - 4.6e-05 23.2 10.4 0.053 13.7 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD23944.1 - 0.00011 22.5 3.4 0.00011 22.5 3.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD23944.1 - 0.013 15.2 7.9 7 6.4 1.7 5.2 3 1 1 4 4 4 0 TPR repeat TPR_14 PF13428.6 PVD23944.1 - 0.058 14.2 2.5 3.9 8.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD23944.1 - 0.21 12.3 3.1 8.2 7.3 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5113 PF17140.4 PVD23944.1 - 0.4 10.5 3.3 14 5.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) TPR_16 PF13432.6 PVD23944.1 - 0.45 11.2 2.3 11 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 PVD23945.1 - 2.7e-10 40.5 0.0 5.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 PVD23945.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain CABIT PF12736.7 PVD23947.1 - 1e-26 93.9 0.0 3.4e-26 92.2 0.0 1.8 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, Pneumo_att_G PF05539.11 PVD23947.1 - 2.4 7.7 7.4 4.3 6.8 7.4 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G EF-hand_7 PF13499.6 PVD23948.1 - 3e-23 82.1 8.4 6.6e-15 55.3 1.7 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD23948.1 - 9.6e-22 74.9 15.8 1.9e-07 30.2 0.1 5.5 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 PVD23948.1 - 1.9e-18 66.0 12.1 2.6e-08 33.6 0.5 4.7 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD23948.1 - 2.1e-17 61.7 6.7 4.7e-08 32.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD23948.1 - 8.9e-16 56.4 11.1 1.6e-06 27.5 0.1 5.8 5 1 1 6 6 6 3 EF-hand domain EF_assoc_2 PF08356.12 PVD23948.1 - 3.4e-05 23.7 0.0 9.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 EF hand associated SPARC_Ca_bdg PF10591.9 PVD23948.1 - 9.5e-05 22.7 1.6 0.00041 20.7 0.1 2.7 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD23948.1 - 0.00038 20.3 1.8 0.3 11.0 0.1 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 PVD23948.1 - 0.0074 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand PTS_2-RNA PF01885.16 PVD23948.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family EF-hand_11 PF08976.11 PVD23948.1 - 0.15 13.0 0.9 0.82 10.6 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain MFS_1 PF07690.16 PVD23949.1 - 1.4e-39 136.0 30.8 7.6e-35 120.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD23949.1 - 1.2e-05 24.4 19.1 0.0017 17.3 2.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 PVD23949.1 - 1.4e-05 24.1 1.7 0.03 13.2 0.0 2.4 2 1 0 2 2 2 2 MFS_1 like family SPC25 PF06703.11 PVD23949.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PRP38 PF03371.15 PVD23950.1 - 1.8e-43 148.4 0.2 2.3e-43 148.1 0.2 1.1 1 0 0 1 1 1 1 PRP38 family SRP-alpha_N PF04086.13 PVD23950.1 - 1.5 8.7 25.3 1.9 8.3 25.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AAA PF00004.29 PVD23951.1 - 5.1e-16 59.3 0.1 1.8e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 PVD23951.1 - 3.1e-13 49.5 0.1 1.6e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 PVD23951.1 - 4.2e-12 46.5 0.4 1.6e-11 44.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 PVD23951.1 - 1.1e-11 45.4 0.1 2.7e-10 40.9 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 PVD23951.1 - 8.2e-11 41.9 0.2 2.3e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 PVD23951.1 - 8.1e-05 23.0 0.2 0.00028 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD23951.1 - 0.00049 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PVD23951.1 - 0.001 18.4 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 PVD23951.1 - 0.0025 17.8 0.6 0.0098 15.8 0.1 2.4 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 PVD23951.1 - 0.035 14.0 0.5 0.72 9.7 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 PVD23951.1 - 0.037 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase TniB PF05621.11 PVD23951.1 - 0.041 13.3 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein tRNA-synt_2b PF00587.25 PVD23952.1 - 1.2e-36 126.3 0.0 1.8e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PVD23952.1 - 3.1e-09 36.8 0.0 8.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain MFS_1 PF07690.16 PVD23953.1 - 1.7e-38 132.5 32.1 2.2e-35 122.2 19.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PVD23953.1 - 0.00045 18.6 3.0 0.2 9.9 0.1 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family SMP_2 PF10144.9 PVD23953.1 - 0.024 14.3 0.3 0.06 13.0 0.3 1.6 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Actin PF00022.19 PVD23954.1 - 4e-152 506.5 0.0 1.3e-151 504.9 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 PVD23955.1 - 8.6e-130 433.0 0.0 2.6e-78 263.4 0.0 2.7 1 1 1 2 2 2 2 Actin Actin PF00022.19 PVD23956.1 - 7.5e-100 334.4 0.3 7.4e-47 159.9 0.0 3.7 2 1 1 3 3 3 3 Actin LURAP PF14854.6 PVD23957.1 - 0.01 15.8 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4530 PF15039.6 PVD23957.1 - 0.074 13.2 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) 3Beta_HSD PF01073.19 PVD23959.1 - 0.00045 19.3 0.0 0.00053 19.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PVD23959.1 - 0.0031 17.0 0.0 0.0036 16.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PVD23959.1 - 0.0044 16.5 0.0 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PVD23959.1 - 0.046 12.9 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LRR_4 PF12799.7 PVD23960.1 - 1.3e-14 54.1 6.1 3.2e-07 30.5 0.2 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD23960.1 - 2.9e-12 46.5 0.2 3.2e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD23960.1 - 0.00083 19.1 4.0 0.028 14.2 1.7 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PVD23960.1 - 0.003 17.9 0.7 88 4.3 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat PMT2_N PF17987.1 PVD23960.1 - 0.08 13.1 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal RTC PF01137.21 PVD23961.1 - 2.7e-87 291.6 1.0 3.1e-87 291.4 1.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PVD23961.1 - 3e-24 85.5 0.1 6e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Fe-S_biosyn PF01521.20 PVD23962.1 - 4.6e-19 68.7 0.0 5.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 PVD23962.1 - 0.0074 16.4 0.0 0.0097 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3853) KH_6 PF15985.5 PVD23963.1 - 4.7e-14 52.5 1.7 5.3e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 KH domain Ank_4 PF13637.6 PVD23964.1 - 3.2e-10 40.3 0.0 2e-07 31.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) BRCT PF00533.26 PVD23964.1 - 4.6e-10 39.7 0.0 4.7e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RNase_H PF00075.24 PVD23964.1 - 3.4e-08 33.8 0.0 8.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Ank_5 PF13857.6 PVD23964.1 - 4.1e-07 30.2 0.0 0.00018 21.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) RTT107_BRCT_5 PF16770.5 PVD23964.1 - 1.4e-06 28.1 0.0 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 PVD23964.1 - 2.7e-06 27.2 0.0 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Ank_2 PF12796.7 PVD23964.1 - 1.2e-05 25.8 0.0 0.00014 22.4 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD23964.1 - 4.8e-05 23.4 0.0 0.0007 19.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat BRCT_2 PF16589.5 PVD23964.1 - 0.00016 22.0 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ank PF00023.30 PVD23964.1 - 0.0015 18.9 1.4 0.037 14.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF4469 PF14734.6 PVD23964.1 - 0.019 15.1 0.1 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold ERAP1_C PF11838.8 PVD23964.1 - 0.19 11.2 1.2 1.3 8.5 0.2 2.7 3 0 0 3 3 3 0 ERAP1-like C-terminal domain Arf PF00025.21 PVD23965.1 - 1.1e-40 138.9 0.0 1.6e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PVD23965.1 - 1.3e-13 51.2 0.1 1.8e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PVD23965.1 - 4.9e-13 49.0 0.5 7.5e-09 35.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PVD23965.1 - 2.1e-12 46.9 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PVD23965.1 - 8.7e-08 32.2 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD23965.1 - 1.6e-07 31.0 0.1 1.9e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD23965.1 - 1.9e-06 27.4 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF4804 PF16062.5 PVD23965.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) Lipocalin_5 PF13924.6 PVD23966.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain RCC1 PF00415.18 PVD23967.1 - 0.14 12.8 19.3 1.2e+02 3.4 0.0 8.4 10 0 0 10 10 10 0 Regulator of chromosome condensation (RCC1) repeat Tmemb_170 PF10190.9 PVD23967.1 - 0.22 11.9 1.7 22 5.5 0.1 2.8 1 1 0 3 3 3 0 Putative transmembrane protein 170 zf-NOSIP PF15906.5 PVD23967.1 - 0.59 10.3 3.1 33 4.7 0.1 3.0 1 1 3 4 4 4 0 Zinc-finger of nitric oxide synthase-interacting protein P22_Cro PF14549.6 PVD23967.1 - 1.1 9.1 17.4 18 5.3 0.3 5.9 1 1 4 5 5 5 0 DNA-binding transcriptional regulator Cro RCC1_2 PF13540.6 PVD23967.1 - 1.3 8.9 22.6 49 3.9 0.1 8.1 5 1 5 10 10 10 0 Regulator of chromosome condensation (RCC1) repeat Sulfotransfer_2 PF03567.14 PVD23969.1 - 0.00093 19.2 0.4 0.0049 16.8 0.3 2.1 2 0 0 2 2 2 1 Sulfotransferase family TCR_zetazeta PF11628.8 PVD23969.1 - 0.15 11.7 1.1 79 3.0 0.0 3.2 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain RVT_1 PF00078.27 PVD23970.1 - 7.2e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 PVD23970.1 - 1.5e-06 27.8 56.6 0.00014 21.5 24.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.18 PVD23971.1 - 1.7e-24 85.3 93.5 9e-10 38.2 26.0 4.2 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) Rio2_N PF09202.11 PVD23971.1 - 5.6 7.2 11.3 65 3.9 0.0 5.8 1 1 4 5 5 5 0 Rio2, N-terminal Collagen PF01391.18 PVD23972.1 - 1.1e-10 41.1 28.7 1.8e-10 40.4 28.7 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Laminin_G_2 PF02210.24 PVD23972.1 - 0.023 15.3 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Laminin_G_3 PF13385.6 PVD23972.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Albumin_I PF08027.11 PVD23973.1 - 2.5 7.8 10.2 7.3 6.3 2.5 2.6 2 0 0 2 2 2 0 Albumin I chain b CarD_CdnL_TRCF PF02559.16 PVD23975.1 - 1e-11 45.4 20.9 3.5e+02 2.0 6.3 14.2 1 1 1 2 2 2 0 CarD-like/TRCF domain bMG1 PF17970.1 PVD23975.1 - 0.00077 19.5 7.2 41 4.3 0.0 7.0 2 1 4 8 8 8 2 Bacterial Alpha-2-macroglobulin MG1 domain DUF2824 PF11039.8 PVD23975.1 - 0.011 15.7 0.6 1.4e+02 2.4 0.0 5.5 5 1 0 6 6 6 0 Protein of unknown function (DUF2824) Neurensin PF14927.6 PVD23976.1 - 9e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Neurensin Ni_hydr_CYTB PF01292.20 PVD23976.1 - 0.052 13.1 0.2 0.077 12.6 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2976 PF11190.8 PVD23976.1 - 0.14 12.0 1.7 0.58 10.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) HOIP-UBA PF16678.5 PVD23978.1 - 0.14 12.1 0.0 57 3.7 0.0 4.0 2 1 2 4 4 4 0 HOIP UBA domain pair FlhD PF05247.13 PVD23978.1 - 4.9 7.5 16.8 6.1 7.2 0.1 5.3 4 2 0 5 5 5 0 Flagellar transcriptional activator (FlhD) AAA_assoc_2 PF16193.5 PVD23979.1 - 0.059 13.7 6.2 3.2 8.1 0.1 4.0 1 1 0 2 2 2 0 AAA C-terminal domain Toxin-deaminase PF14424.6 PVD23979.1 - 0.15 12.1 8.7 28 4.8 0.2 4.8 5 0 0 5 5 5 0 The BURPS668_1122 family of deaminases Methyltransf_30 PF05430.11 PVD23980.1 - 0.00026 20.9 0.3 48 3.8 0.0 4.9 2 2 3 5 5 5 0 S-adenosyl-L-methionine-dependent methyltransferase AAA_assoc_2 PF16193.5 PVD23980.1 - 0.0035 17.6 23.2 0.51 10.7 0.2 7.0 3 2 2 5 5 5 3 AAA C-terminal domain CEP44 PF15007.6 PVD23980.1 - 0.11 12.7 0.3 44 4.2 0.0 4.0 2 2 3 5 5 5 0 Centrosomal spindle body, CEP44 DRAT PF07357.11 PVD23980.1 - 0.46 9.6 3.0 3 7.0 0.1 2.4 2 1 0 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Methyltransf_30 PF05430.11 PVD23981.1 - 0.0012 18.7 0.1 29 4.6 0.0 5.2 2 2 2 5 5 5 1 S-adenosyl-L-methionine-dependent methyltransferase DUF1492 PF07374.11 PVD23981.1 - 0.009 16.2 0.4 84 3.4 0.0 5.6 2 2 6 8 8 8 0 Protein of unknown function (DUF1492) AAA_assoc_2 PF16193.5 PVD23981.1 - 1.6 9.1 31.5 3.9 7.9 0.6 8.9 2 2 6 9 9 9 0 AAA C-terminal domain AIG1 PF04548.16 PVD23982.1 - 7.2e-33 113.7 0.1 3.3e-25 88.7 0.0 3.1 3 0 0 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 PVD23982.1 - 2.9e-09 37.0 0.1 7.8e-07 29.2 0.0 2.6 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD23982.1 - 6.5e-05 22.6 0.3 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD23982.1 - 0.0004 20.5 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin family TniB PF05621.11 PVD23982.1 - 0.00096 18.6 0.0 0.048 13.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 PVD23982.1 - 0.0014 18.0 0.6 0.031 13.6 0.0 2.5 2 1 0 3 3 3 1 FtsK/SpoIIIE family AAA_24 PF13479.6 PVD23982.1 - 0.0024 17.6 0.9 0.59 9.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD23982.1 - 0.0054 16.3 0.1 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 PVD23982.1 - 0.011 16.3 0.7 0.28 11.7 0.2 2.4 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 PVD23982.1 - 0.02 15.4 1.0 3.8 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 PVD23982.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_10 PF12846.7 PVD23982.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain G-alpha PF00503.20 PVD23982.1 - 0.031 13.4 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 PVD23982.1 - 0.033 14.6 0.2 0.83 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 PVD23982.1 - 0.044 12.8 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 PVD23982.1 - 0.06 13.1 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 PVD23982.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 PVD23982.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 PVD23982.1 - 0.11 12.0 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 PVD23982.1 - 0.14 11.3 0.4 1 8.4 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PVD23982.1 - 0.15 12.5 0.1 2 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 PVD23983.1 - 5.4e-43 146.8 0.0 7.2e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23983.1 - 1.6e-10 41.1 0.0 4.6e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23983.1 - 2.3e-05 24.5 1.3 0.015 15.4 0.1 2.6 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 PVD23983.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 PVD23983.1 - 0.0017 18.3 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PVD23983.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD23983.1 - 0.01 16.3 2.5 0.029 14.9 2.5 1.9 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 PVD23983.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PVD23983.1 - 0.041 13.3 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GGDEF_2 PF17853.1 PVD23983.1 - 0.051 13.8 0.2 0.51 10.6 0.2 2.6 1 1 0 1 1 1 0 GGDEF-like domain AAA_22 PF13401.6 PVD23983.1 - 0.06 13.6 0.0 0.41 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD23983.1 - 0.16 12.4 0.5 0.97 9.8 0.5 2.4 1 1 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 PVD23984.1 - 1.2e-21 77.1 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23984.1 - 2e-09 37.6 0.0 5.6e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23984.1 - 6.8e-08 32.7 1.1 0.0022 18.1 0.6 2.7 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD23984.1 - 1.4e-05 25.1 0.3 2.1e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase Gtr1_RagA PF04670.12 PVD23984.1 - 0.00043 19.7 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PVD23984.1 - 0.0033 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RNA_helicase PF00910.22 PVD23984.1 - 0.0033 17.8 0.0 0.01 16.2 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 PVD23984.1 - 0.0045 16.7 1.2 0.25 11.1 0.7 2.5 1 1 1 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD23984.1 - 0.0083 16.6 1.2 0.015 15.8 0.9 1.6 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 PVD23984.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 PVD23984.1 - 0.037 13.4 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PVD23984.1 - 0.04 13.7 0.2 0.076 12.8 0.2 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 PVD23984.1 - 0.041 14.1 0.2 0.077 13.2 0.2 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD23984.1 - 0.045 14.0 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PVD23984.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 PVD23984.1 - 0.14 11.2 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 PVD23984.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 PVD23984.1 - 0.16 11.4 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 PVD23984.1 - 0.16 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 PVD23985.1 - 9.3e-19 67.6 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23985.1 - 3.1e-08 33.7 0.0 3.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD23985.1 - 9.7e-05 22.9 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD23985.1 - 0.00011 22.1 0.3 0.00017 21.5 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 PVD23985.1 - 0.012 16.1 0.7 0.02 15.4 0.5 1.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 PVD23985.1 - 0.013 15.5 3.2 0.028 14.5 0.4 2.0 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 PVD23985.1 - 0.047 13.1 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 PVD23985.1 - 0.06 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 PVD23985.1 - 0.063 12.3 0.1 0.078 12.0 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 PVD23985.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 PVD23985.1 - 0.16 11.5 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 PVD23986.1 - 6.9e-118 391.5 14.8 2.9e-29 101.9 0.1 5.0 4 1 1 5 5 5 5 AIG1 family MMR_HSR1 PF01926.23 PVD23986.1 - 1.4e-33 115.4 0.5 1.2e-06 28.6 0.1 5.6 5 0 0 5 5 5 4 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD23986.1 - 4e-17 62.6 3.5 0.003 17.5 0.1 4.7 4 0 0 4 4 4 4 RsgA GTPase ABC_tran PF00005.27 PVD23986.1 - 7.2e-12 46.0 3.9 0.0008 19.9 0.0 4.8 4 1 0 4 4 4 3 ABC transporter AAA_29 PF13555.6 PVD23986.1 - 2.8e-10 39.8 3.6 0.17 11.6 0.0 4.4 4 0 0 4 4 4 3 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD23986.1 - 3.7e-10 40.1 12.7 0.00033 20.8 0.1 5.9 4 3 1 5 5 5 2 Dynamin family Septin PF00735.18 PVD23986.1 - 3.2e-09 36.5 8.6 0.094 12.0 0.0 5.0 5 0 0 5 5 5 3 Septin FtsK_SpoIIIE PF01580.18 PVD23986.1 - 1.4e-08 34.4 6.4 0.027 13.8 0.0 4.6 5 0 0 5 5 4 3 FtsK/SpoIIIE family Roc PF08477.13 PVD23986.1 - 5.7e-08 33.0 6.0 1.4 9.1 0.0 5.9 5 2 1 6 6 5 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 PVD23986.1 - 1.1e-06 28.8 1.8 0.029 14.5 0.1 5.7 5 1 1 6 6 4 1 AAA domain AAA_24 PF13479.6 PVD23986.1 - 1.1e-06 28.5 1.1 1 9.1 0.0 4.7 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 PVD23986.1 - 1.6e-06 27.9 0.1 1.1 9.0 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain RNA_helicase PF00910.22 PVD23986.1 - 2e-06 28.1 0.8 1.6 9.2 0.0 5.2 4 0 0 4 4 4 1 RNA helicase Guanylate_kin PF00625.21 PVD23986.1 - 3.5e-06 26.8 1.6 0.8 9.4 0.0 4.7 4 0 0 4 4 4 2 Guanylate kinase IIGP PF05049.13 PVD23986.1 - 5.2e-06 25.8 0.3 0.84 8.6 0.2 3.6 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 PVD23986.1 - 7.3e-06 25.2 0.1 0.23 10.5 0.0 4.0 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_18 PF13238.6 PVD23986.1 - 1.3e-05 25.8 8.3 0.24 12.0 0.1 5.4 5 1 0 5 5 4 1 AAA domain PduV-EutP PF10662.9 PVD23986.1 - 1.5e-05 24.8 2.4 4.4 7.1 0.0 4.7 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PVD23986.1 - 2.5e-05 23.8 4.1 4 6.8 0.1 4.6 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PVD23986.1 - 2.5e-05 24.6 3.4 1.8 8.9 0.0 5.4 4 2 0 4 4 4 1 AAA domain AAA_16 PF13191.6 PVD23986.1 - 5.1e-05 23.7 0.3 4.9 7.5 0.0 4.8 4 2 0 4 4 4 0 AAA ATPase domain AAA_10 PF12846.7 PVD23986.1 - 6.2e-05 22.1 0.3 0.36 9.7 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain DUF815 PF05673.13 PVD23986.1 - 0.0003 20.0 1.5 1.2 8.2 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 PVD23986.1 - 0.00032 20.2 8.1 0.13 11.8 0.4 3.6 4 0 0 4 4 3 2 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 PVD23986.1 - 0.00057 18.9 0.2 1.4 7.7 0.0 3.7 4 0 0 4 4 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 PVD23986.1 - 0.00075 19.8 3.1 0.47 10.7 0.0 5.2 7 0 0 7 7 5 1 AAA domain G-alpha PF00503.20 PVD23986.1 - 0.0011 18.3 9.3 0.46 9.6 0.2 4.9 3 2 0 3 3 3 1 G-protein alpha subunit Sigma54_activ_2 PF14532.6 PVD23986.1 - 0.0024 18.0 0.0 17 5.5 0.0 4.0 4 0 0 4 4 3 0 Sigma-54 interaction domain Hpr_kinase_C PF07475.12 PVD23986.1 - 0.0041 16.7 0.6 9.6 5.7 0.0 3.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain G_path_suppress PF15991.5 PVD23986.1 - 0.0044 17.2 8.8 0.66 10.1 0.0 4.2 5 0 0 5 5 4 1 G-protein pathway suppressor Gtr1_RagA PF04670.12 PVD23986.1 - 0.0061 15.9 14.9 0.1 11.9 0.1 5.6 4 4 1 5 5 5 1 Gtr1/RagA G protein conserved region AAA PF00004.29 PVD23986.1 - 0.0083 16.5 1.7 32 5.0 0.0 4.6 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 PVD23986.1 - 0.0091 15.6 9.8 8.3 5.9 0.1 5.7 6 1 0 6 6 5 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 PVD23986.1 - 0.013 15.5 0.4 35 4.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 PVD23986.1 - 0.013 15.0 2.1 5.7 6.3 0.0 4.0 4 0 0 4 4 4 0 Poxvirus A32 protein DUF87 PF01935.17 PVD23986.1 - 0.022 14.9 18.6 1.2 9.1 0.0 5.8 7 0 0 7 7 6 0 Helicase HerA, central domain Ras PF00071.22 PVD23986.1 - 0.03 13.9 11.2 30 4.2 0.0 7.0 5 2 2 8 8 8 0 Ras family Arf PF00025.21 PVD23986.1 - 0.031 13.7 4.0 6.9 6.1 0.0 4.9 4 1 1 5 5 5 0 ADP-ribosylation factor family Myosin_TH1 PF06017.13 PVD23986.1 - 0.049 13.3 2.4 3.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Unconventional myosin tail, actin- and lipid-binding IstB_IS21 PF01695.17 PVD23986.1 - 0.052 13.3 0.1 31 4.2 0.0 3.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Rad17 PF03215.15 PVD23986.1 - 0.055 13.4 1.0 0.32 10.9 0.0 2.8 4 0 0 4 4 2 0 Rad17 P-loop domain TniB PF05621.11 PVD23986.1 - 0.073 12.5 5.0 5.3 6.4 0.0 4.3 6 0 0 6 6 4 0 Bacterial TniB protein SMC_N PF02463.19 PVD23986.1 - 0.097 12.1 5.4 4.2 6.7 0.1 4.0 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain DUF2075 PF09848.9 PVD23986.1 - 0.11 11.7 5.3 15 4.7 0.2 4.4 4 1 0 5 5 4 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 PVD23986.1 - 1.5 8.7 8.4 7.8 6.4 0.4 4.8 5 1 0 5 5 4 0 NACHT domain CobU PF02283.16 PVD23986.1 - 4.5 6.8 6.9 28 4.2 0.0 4.3 6 0 0 6 6 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AIG1 PF04548.16 PVD23987.1 - 2.9e-62 209.8 0.0 9.7e-48 162.3 0.0 2.2 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD23987.1 - 1.4e-14 54.1 0.3 2.7e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23987.1 - 2.2e-08 34.4 8.0 0.059 13.4 0.3 4.0 3 1 1 4 4 4 3 Dynamin family RsgA_GTPase PF03193.16 PVD23987.1 - 4.9e-06 26.5 4.7 0.031 14.2 0.1 2.6 2 1 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 PVD23987.1 - 1.1e-05 26.0 5.4 0.02 15.4 0.0 2.8 2 1 1 3 3 3 2 ABC transporter T2SSE PF00437.20 PVD23987.1 - 2.3e-05 23.6 0.1 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 PVD23987.1 - 4.3e-05 23.2 1.6 0.098 12.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 PVD23987.1 - 0.00039 20.0 0.3 0.72 9.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 PVD23987.1 - 0.00059 20.2 1.3 0.78 10.2 0.0 3.1 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.13 PVD23987.1 - 0.0011 18.2 0.5 0.08 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Roc PF08477.13 PVD23987.1 - 0.0014 18.9 0.7 0.25 11.6 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 PVD23987.1 - 0.0014 18.4 1.0 1.5 8.5 0.1 3.0 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 PVD23987.1 - 0.0014 18.4 0.5 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 PVD23987.1 - 0.0015 17.9 1.5 0.055 12.7 0.0 2.7 3 0 0 3 3 3 1 Septin AAA_22 PF13401.6 PVD23987.1 - 0.0018 18.6 3.1 0.78 10.0 0.0 2.9 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 PVD23987.1 - 0.0021 17.8 0.3 0.47 10.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain FeoB_N PF02421.18 PVD23987.1 - 0.003 17.1 0.1 0.082 12.4 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 PVD23987.1 - 0.0049 16.8 3.6 5.4 6.9 0.2 3.4 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.17 PVD23987.1 - 0.0056 16.8 10.8 3.5 7.7 0.8 3.3 2 1 1 3 3 3 2 Helicase HerA, central domain SMC_N PF02463.19 PVD23987.1 - 0.0069 15.8 0.7 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 PVD23987.1 - 0.011 16.3 5.5 1.4 9.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 PVD23987.1 - 0.013 14.8 0.7 4.1 6.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 PVD23987.1 - 0.02 15.3 2.1 2.1 8.7 1.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 PVD23987.1 - 0.026 14.0 0.6 1.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DAP3 PF10236.9 PVD23987.1 - 0.052 12.7 1.2 3.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.17 PVD23987.1 - 0.059 13.1 0.2 12 5.6 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 PVD23987.1 - 0.077 13.1 0.6 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 PVD23987.1 - 0.12 11.8 6.3 9 5.6 3.6 3.1 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 PVD23987.1 - 0.12 12.4 1.4 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PVD23987.1 - 0.13 11.5 2.1 7.6 5.8 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_10 PF12846.7 PVD23987.1 - 0.14 11.1 4.9 1.2 8.0 0.3 2.8 2 1 1 3 3 3 0 AAA-like domain Symplekin_C PF12295.8 PVD23987.1 - 0.14 12.2 0.3 0.2 11.7 0.3 1.2 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal AAA PF00004.29 PVD23987.1 - 0.21 12.0 1.0 5.9 7.3 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 PVD23987.1 - 0.42 9.7 4.0 2.1 7.4 0.2 2.6 1 1 0 2 2 2 0 G-protein alpha subunit IIGP PF05049.13 PVD23987.1 - 0.63 9.0 5.6 6.1 5.8 0.1 2.8 2 2 1 3 3 3 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 PVD23988.1 - 1.6e-36 125.6 0.0 2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23988.1 - 6.9e-08 32.6 0.1 1.4e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD23988.1 - 0.0069 16.3 0.3 0.016 15.2 0.3 1.6 1 0 0 1 1 1 1 RsgA GTPase Corona_M PF01635.18 PVD23988.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Dynamin_N PF00350.23 PVD23988.1 - 0.027 14.5 0.8 0.063 13.3 0.5 1.7 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 PVD23988.1 - 0.035 14.6 3.0 0.1 13.1 1.2 2.3 2 1 0 3 3 3 0 ABC transporter IIGP PF05049.13 PVD23988.1 - 0.08 12.0 0.2 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GGDEF_2 PF17853.1 PVD23988.1 - 0.11 12.7 0.1 0.51 10.6 0.0 1.9 1 1 0 2 2 2 0 GGDEF-like domain SMC_N PF02463.19 PVD23988.1 - 0.17 11.3 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AIG1 PF04548.16 PVD23989.1 - 1e-38 132.8 8.2 4e-29 101.5 0.2 3.1 3 0 0 3 3 3 3 AIG1 family MMR_HSR1 PF01926.23 PVD23989.1 - 1.8e-07 31.3 0.6 7.1e-06 26.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23989.1 - 4.2e-05 23.7 3.7 0.00066 19.8 0.0 3.0 3 1 0 3 3 3 1 Dynamin family Cofilin_ADF PF00241.20 PVD23989.1 - 0.00068 19.4 0.0 0.042 13.7 0.0 2.5 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein RsgA_GTPase PF03193.16 PVD23989.1 - 0.002 18.1 0.0 0.0065 16.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD23989.1 - 0.019 15.5 1.2 0.073 13.6 0.6 2.4 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.6 PVD23989.1 - 0.023 14.4 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 PVD23989.1 - 0.033 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain GFO_IDH_MocA PF01408.22 PVD23989.1 - 0.073 13.9 0.0 0.27 12.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AAA_7 PF12775.7 PVD23989.1 - 0.11 12.0 0.1 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Lectin_C PF00059.21 PVD23990.1 - 1.6e-18 67.4 3.7 1.4e-15 57.9 1.3 2.7 2 1 1 3 3 3 2 Lectin C-type domain UL45 PF05473.12 PVD23990.1 - 1.7e-09 37.6 1.2 7.3e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 PVD23990.1 - 0.00029 20.2 3.3 0.04 13.2 0.7 2.3 2 0 0 2 2 2 2 Chordopoxvirus A33R protein AIG1 PF04548.16 PVD23991.1 - 2e-06 27.3 0.1 2.8e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 AIG1 family DUF2207 PF09972.9 PVD23991.1 - 0.0028 16.5 0.1 0.0032 16.3 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Lectin_C PF00059.21 PVD23992.1 - 1e-18 68.1 6.6 4e-10 40.4 0.4 2.2 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD23992.1 - 0.0004 20.1 0.8 0.0041 16.8 0.1 2.2 1 1 1 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 PVD23992.1 - 0.028 13.7 0.3 0.044 13.1 0.3 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein AIG1 PF04548.16 PVD23993.1 - 3.4e-56 189.9 7.0 5.8e-24 84.6 0.5 4.2 2 2 2 4 4 4 4 AIG1 family MMR_HSR1 PF01926.23 PVD23993.1 - 1.6e-06 28.1 2.9 0.042 13.9 0.5 4.4 2 2 1 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23993.1 - 0.00029 20.9 0.5 4.1 7.4 0.1 3.9 3 1 1 4 4 4 2 Dynamin family T2SSE PF00437.20 PVD23993.1 - 0.039 13.0 0.1 0.93 8.5 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 PVD23993.1 - 0.072 12.8 0.6 1.7 8.5 0.4 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD23993.1 - 0.34 11.4 2.7 1.4 9.4 1.8 2.5 2 1 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 PVD23993.1 - 0.4 10.4 4.6 19 5.0 1.6 3.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 PVD23993.1 - 2 8.4 5.5 2.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain AIG1 PF04548.16 PVD23994.1 - 1.1e-44 152.3 0.3 1.4e-44 152.0 0.3 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23994.1 - 2e-11 44.0 0.1 4.5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23994.1 - 0.00018 21.6 2.9 0.43 10.6 1.1 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD23994.1 - 0.00049 20.0 1.6 0.00059 19.8 0.4 1.7 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 PVD23994.1 - 0.0042 16.5 0.1 0.0067 15.8 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 PVD23994.1 - 0.031 14.8 1.5 0.038 14.5 0.1 1.8 2 1 0 2 2 2 0 ABC transporter Septin PF00735.18 PVD23994.1 - 0.032 13.5 2.0 0.23 10.7 0.4 2.2 1 1 1 2 2 2 0 Septin SRPRB PF09439.10 PVD23994.1 - 0.034 13.6 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 PVD23994.1 - 0.04 13.4 0.1 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 PVD23994.1 - 0.093 13.1 0.1 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 PVD23994.1 - 1 9.4 5.0 2.8 8.0 1.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AIG1 PF04548.16 PVD23995.1 - 1.1e-26 93.5 0.0 1.3e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23995.1 - 1.2e-07 31.8 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23995.1 - 0.00045 20.3 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 PVD23995.1 - 0.00061 20.3 0.0 0.00061 20.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD23995.1 - 0.069 13.0 1.1 0.11 12.4 1.1 1.4 1 1 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 PVD23995.1 - 0.096 11.6 0.2 0.093 11.6 0.2 1.2 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 PVD23995.1 - 0.1 12.7 0.4 0.29 11.2 0.3 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 PVD23995.1 - 0.21 11.4 1.0 0.4 10.5 1.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 PVD23996.1 - 2.8e-47 160.8 0.0 3.7e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23996.1 - 2.2e-08 34.1 0.0 5.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD23996.1 - 0.0052 17.3 0.1 0.01 16.4 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 PVD23996.1 - 0.0052 16.9 1.9 0.07 13.2 0.3 2.6 3 0 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 PVD23996.1 - 0.012 15.5 3.3 0.017 15.0 1.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 PVD23996.1 - 0.12 12.7 0.1 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PVD23997.1 - 4.4e-20 71.9 0.0 5.5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 AIG1 family DUF3040 PF11239.8 PVD23997.1 - 0.03 14.6 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SPC12 PF06645.13 PVD23997.1 - 0.094 12.8 0.4 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) AIG1 PF04548.16 PVD23998.1 - 1.9e-33 115.6 0.1 2.4e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23998.1 - 1.7e-10 41.0 0.1 3.1e-10 40.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD23998.1 - 1.3e-06 28.6 0.3 2e-06 28.0 0.3 1.6 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 PVD23998.1 - 8.8e-05 23.0 0.1 0.00017 22.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD23998.1 - 0.001 19.0 1.0 0.0021 18.0 0.7 1.7 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PVD23998.1 - 0.0077 15.9 0.3 0.018 14.8 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Guanylate_kin PF00625.21 PVD23998.1 - 0.013 15.2 0.2 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase SRPRB PF09439.10 PVD23998.1 - 0.013 14.9 0.4 0.025 14.0 0.1 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SMC_N PF02463.19 PVD23998.1 - 0.015 14.8 0.2 0.038 13.4 0.1 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 PVD23998.1 - 0.018 14.7 0.2 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_15 PF13175.6 PVD23998.1 - 0.021 14.5 1.8 0.039 13.7 1.8 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 PVD23998.1 - 0.026 14.0 0.3 0.051 13.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_10 PF12846.7 PVD23998.1 - 0.046 12.6 0.2 0.067 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 PVD23998.1 - 0.05 13.9 0.1 0.12 12.6 0.1 1.6 1 1 1 2 2 2 0 AAA domain IIGP PF05049.13 PVD23998.1 - 0.058 12.4 0.4 0.12 11.5 0.4 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA PF00004.29 PVD23998.1 - 0.059 13.8 0.5 0.18 12.2 0.2 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PVD23998.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PVD23998.1 - 0.092 13.3 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 PVD23998.1 - 0.3 10.1 1.1 0.62 9.1 1.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.16 PVD23999.1 - 4.2e-24 85.1 0.0 4.7e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD23999.1 - 3.8e-07 30.2 0.0 4.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD23999.1 - 0.00045 20.2 0.1 0.00073 19.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PVD23999.1 - 0.0027 18.2 0.0 0.0029 18.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 PVD23999.1 - 0.0029 17.7 0.4 0.94 9.5 0.2 2.1 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.12 PVD23999.1 - 0.026 13.9 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD23999.1 - 0.027 14.7 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 PVD23999.1 - 0.047 13.2 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.22 PVD23999.1 - 0.071 12.7 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Ras family AIG1 PF04548.16 PVD24000.1 - 7.3e-70 234.6 1.3 1.2e-25 90.0 0.0 4.5 3 1 1 4 4 4 4 AIG1 family MMR_HSR1 PF01926.23 PVD24000.1 - 1.2e-21 77.0 0.0 9e-08 32.2 0.0 4.2 4 0 0 4 4 4 3 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD24000.1 - 3.8e-08 33.0 2.1 0.032 14.0 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD24000.1 - 3.4e-07 30.3 0.8 0.2 11.6 0.0 3.6 3 0 0 3 3 3 2 RsgA GTPase Septin PF00735.18 PVD24000.1 - 1.5e-06 27.7 3.4 0.017 14.4 0.0 3.5 4 0 0 4 4 3 2 Septin ABC_tran PF00005.27 PVD24000.1 - 1.6e-06 28.7 0.5 0.056 14.0 0.0 3.7 4 0 0 4 4 3 2 ABC transporter Dynamin_N PF00350.23 PVD24000.1 - 5e-06 26.7 9.0 0.18 11.8 0.0 4.9 4 1 1 5 5 5 3 Dynamin family AAA_18 PF13238.6 PVD24000.1 - 1.3e-05 25.8 2.2 0.085 13.4 0.0 4.4 3 1 1 4 4 4 1 AAA domain T2SSE PF00437.20 PVD24000.1 - 5.9e-05 22.3 0.1 0.19 10.8 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_7 PF12775.7 PVD24000.1 - 8.8e-05 22.1 0.2 0.047 13.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 PVD24000.1 - 0.00011 21.6 0.9 0.095 12.0 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family Sigma54_activat PF00158.26 PVD24000.1 - 0.00012 21.9 0.0 0.44 10.2 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain G-alpha PF00503.20 PVD24000.1 - 0.00032 20.0 2.4 0.66 9.1 0.0 4.1 5 0 0 5 5 5 1 G-protein alpha subunit AAA_24 PF13479.6 PVD24000.1 - 0.0005 19.9 0.3 0.88 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PVD24000.1 - 0.00091 19.6 0.0 3.3 8.1 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain Rad17 PF03215.15 PVD24000.1 - 0.0014 18.6 0.1 0.69 9.8 0.0 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 PVD24000.1 - 0.0018 18.6 0.6 1.4 9.2 0.0 3.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PVD24000.1 - 0.0024 18.3 0.1 5.4 7.5 0.0 3.1 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 PVD24000.1 - 0.0046 16.4 0.3 0.83 9.0 0.0 3.1 3 1 0 3 3 3 1 Bacterial TniB protein AAA_10 PF12846.7 PVD24000.1 - 0.006 15.5 1.4 0.21 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_33 PF13671.6 PVD24000.1 - 0.0099 16.0 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 PVD24000.1 - 0.011 15.4 0.3 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Cofilin_ADF PF00241.20 PVD24000.1 - 0.012 15.4 0.3 4.2 7.2 0.1 3.0 3 0 0 3 3 2 0 Cofilin/tropomyosin-type actin-binding protein GTP_EFTU PF00009.27 PVD24000.1 - 0.014 14.9 2.3 0.51 9.8 0.0 3.4 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain Roc PF08477.13 PVD24000.1 - 0.022 15.0 0.3 25 5.1 0.0 3.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PVD24000.1 - 0.045 13.1 0.4 17 4.6 0.0 3.3 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Bromodomain PF00439.25 PVD24000.1 - 0.061 13.4 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Bromodomain SMC_N PF02463.19 PVD24000.1 - 0.062 12.7 0.5 8.8 5.7 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Sigma54_activ_2 PF14532.6 PVD24000.1 - 0.072 13.2 0.9 5.8 7.0 0.0 3.2 4 0 0 4 4 2 0 Sigma-54 interaction domain AAA PF00004.29 PVD24000.1 - 0.11 12.9 0.0 27 5.2 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD24000.1 - 0.11 12.4 0.1 23 5.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.12 PVD24000.1 - 0.19 11.3 0.2 20 4.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IIGP PF05049.13 PVD24000.1 - 0.21 10.6 2.6 3 6.8 0.1 2.9 3 1 0 3 3 2 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 PVD24000.1 - 0.36 10.7 4.4 33 4.3 0.1 4.0 3 1 1 4 4 4 0 NACHT domain Pox_A32 PF04665.12 PVD24000.1 - 0.43 10.0 2.7 26 4.1 0.0 3.7 4 0 0 4 4 4 0 Poxvirus A32 protein DUF87 PF01935.17 PVD24000.1 - 4.4 7.3 7.2 6.6 6.8 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AIG1 PF04548.16 PVD24001.1 - 5.2e-51 173.0 7.7 2.6e-23 82.5 0.0 3.0 2 1 1 3 3 3 3 AIG1 family MMR_HSR1 PF01926.23 PVD24001.1 - 3.1e-14 53.0 1.6 6.9e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24001.1 - 2e-07 31.1 1.7 0.0089 15.9 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PVD24001.1 - 2.4e-06 27.7 5.1 0.17 11.9 0.1 3.6 4 0 0 4 4 4 2 Dynamin family Roc PF08477.13 PVD24001.1 - 6.8e-06 26.3 0.7 0.11 12.7 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 PVD24001.1 - 0.0001 21.5 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 PVD24001.1 - 0.00096 19.7 7.6 0.13 12.8 2.5 2.7 1 1 1 2 2 2 2 ABC transporter FeoB_N PF02421.18 PVD24001.1 - 0.001 18.6 0.8 0.38 10.3 0.0 3.1 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_24 PF13479.6 PVD24001.1 - 0.0011 18.7 0.4 0.45 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 PVD24001.1 - 0.0016 18.0 0.1 0.88 9.1 0.0 2.7 2 0 0 2 2 2 1 Ras family AAA_7 PF12775.7 PVD24001.1 - 0.0026 17.3 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 PVD24001.1 - 0.0034 17.8 1.6 1.1 9.6 0.3 2.4 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 PVD24001.1 - 0.0044 16.8 1.3 2.9 7.6 0.0 3.0 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 PVD24001.1 - 0.0059 16.4 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 PVD24001.1 - 0.013 15.2 0.4 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Actin_micro PF17003.5 PVD24001.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative actin-like family Septin PF00735.18 PVD24001.1 - 0.019 14.3 0.1 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Septin Sigma54_activat PF00158.26 PVD24001.1 - 0.019 14.7 0.1 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_PrkA PF08298.11 PVD24001.1 - 0.025 13.5 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain DUF815 PF05673.13 PVD24001.1 - 0.038 13.2 2.7 2.4 7.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF815) T2SSE PF00437.20 PVD24001.1 - 0.046 12.8 2.5 4.7 6.2 0.2 3.0 2 1 1 3 3 3 0 Type II/IV secretion system protein AAA_18 PF13238.6 PVD24001.1 - 0.048 14.2 4.1 3.1 8.3 1.3 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PVD24001.1 - 0.052 13.9 0.9 5 7.6 0.1 2.9 3 0 0 3 3 3 0 RNA helicase AAA_21 PF13304.6 PVD24001.1 - 0.067 13.0 0.3 6.1 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.12 PVD24001.1 - 0.069 12.5 0.0 6.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Guanylate_kin PF00625.21 PVD24001.1 - 0.086 12.5 1.0 7.7 6.2 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase DAP3 PF10236.9 PVD24001.1 - 0.12 11.5 0.8 3.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 HemS PF05171.12 PVD24001.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain FtsK_SpoIIIE PF01580.18 PVD24001.1 - 0.28 10.5 2.5 14 4.9 0.1 2.9 2 1 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 PVD24001.1 - 1.2 9.5 4.7 1.3e+02 3.0 4.6 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PVD24001.1 - 1.9 8.7 5.6 22 5.2 0.9 3.2 2 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 PVD24001.1 - 3.3 8.0 5.8 7.2 6.9 1.2 2.7 1 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 PVD24002.1 - 3e-13 49.6 0.2 4e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 AIG1 family CSD PF00313.22 PVD24003.1 - 0.00087 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain AIG1 PF04548.16 PVD24004.1 - 7.9e-52 175.7 0.0 9.2e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24004.1 - 2.9e-09 37.0 0.1 8.9e-09 35.4 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24004.1 - 0.00067 19.6 0.2 0.0016 18.4 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 PVD24004.1 - 0.0053 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 PVD24004.1 - 0.012 15.6 1.8 0.13 12.3 0.2 2.5 2 1 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 PVD24004.1 - 0.014 15.9 0.9 0.021 15.3 0.9 1.7 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 PVD24004.1 - 0.057 12.9 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.13 PVD24004.1 - 0.094 11.9 0.1 2 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 PVD24004.1 - 0.16 11.7 0.0 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 PVD24005.1 - 3.5e-29 101.6 0.0 4.3e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24005.1 - 0.00036 20.6 0.1 0.00053 20.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD24005.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PVD24005.1 - 0.041 14.2 0.0 0.28 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PVD24005.1 - 0.043 14.2 0.0 0.87 10.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 PVD24005.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 PVD24005.1 - 0.072 13.2 0.7 0.16 12.0 0.7 1.9 1 1 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 PVD24005.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 PVD24005.1 - 0.18 12.3 2.0 0.4 11.2 2.0 1.9 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.16 PVD24006.1 - 7.4e-32 110.4 0.0 9.2e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24006.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD24006.1 - 0.14 12.7 0.6 0.25 11.8 0.6 1.5 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.16 PVD24007.1 - 1e-06 28.2 0.2 1.2e-06 28.0 0.2 1.1 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 PVD24007.1 - 5.6e-05 23.1 0.1 5.6e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PVD24007.1 - 0.00037 21.0 0.2 0.00038 21.0 0.2 1.2 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 PVD24007.1 - 0.00041 20.4 0.1 0.00044 20.3 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 PVD24007.1 - 0.0057 16.1 0.0 0.0065 15.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 PVD24007.1 - 0.0059 16.7 0.2 0.0066 16.5 0.2 1.1 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 PVD24007.1 - 0.007 16.1 0.1 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 PVD24007.1 - 0.0077 15.5 0.0 0.0087 15.4 0.0 1.0 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 PVD24007.1 - 0.0087 15.6 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 PVD24007.1 - 0.0088 15.4 0.1 0.0091 15.4 0.1 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 PVD24007.1 - 0.028 13.5 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.20 PVD24007.1 - 0.036 13.2 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 PVD24007.1 - 0.047 14.2 0.2 0.049 14.2 0.2 1.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PVD24007.1 - 0.055 13.2 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 PVD24007.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Guanylate kinase AAA_28 PF13521.6 PVD24007.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 PVD24008.1 - 6.6e-08 32.1 2.7 7e-08 32.1 1.1 1.7 1 1 1 2 2 2 1 AIG1 family ABC_tran PF00005.27 PVD24008.1 - 0.00016 22.2 0.0 0.00019 22.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter IncE PF17627.2 PVD24008.1 - 0.00027 20.9 0.7 0.00042 20.3 0.7 1.2 1 0 0 1 1 1 1 Inclusion membrane protein E RsgA_GTPase PF03193.16 PVD24008.1 - 0.002 18.1 0.4 0.0028 17.6 0.4 1.4 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PVD24008.1 - 0.0024 17.9 0.6 0.0046 17.0 0.5 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24008.1 - 0.0085 16.2 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 PVD24008.1 - 0.044 13.5 0.1 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PVD24008.1 - 0.053 14.0 0.8 0.053 14.0 0.8 1.7 1 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 PVD24009.1 - 4.8e-72 241.7 3.5 1.8e-26 92.8 0.0 5.1 3 1 2 5 5 5 5 AIG1 family MMR_HSR1 PF01926.23 PVD24009.1 - 1.1e-21 77.0 0.8 1.1e-08 35.2 0.0 4.3 3 1 0 3 3 3 3 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24009.1 - 2.6e-13 50.2 4.4 0.00012 22.0 0.1 3.6 3 0 0 3 3 3 3 RsgA GTPase Dynamin_N PF00350.23 PVD24009.1 - 5e-13 49.4 7.4 0.0085 16.2 0.6 5.3 3 2 2 5 5 5 3 Dynamin family FtsK_SpoIIIE PF01580.18 PVD24009.1 - 1e-07 31.6 0.9 0.33 10.3 0.0 3.7 3 0 0 3 3 3 3 FtsK/SpoIIIE family ABC_tran PF00005.27 PVD24009.1 - 1.3e-07 32.2 3.6 0.18 12.3 1.7 3.8 3 1 0 3 3 3 3 ABC transporter Septin PF00735.18 PVD24009.1 - 2.6e-07 30.2 1.0 0.21 10.8 0.1 4.1 3 1 1 4 4 4 3 Septin AAA_29 PF13555.6 PVD24009.1 - 3.5e-07 29.9 3.1 0.51 10.1 0.2 3.6 3 0 0 3 3 3 3 P-loop containing region of AAA domain AAA_24 PF13479.6 PVD24009.1 - 2.4e-06 27.4 1.4 1.6 8.5 0.0 3.7 4 0 0 4 4 3 3 AAA domain AAA_22 PF13401.6 PVD24009.1 - 3.4e-06 27.4 0.1 0.35 11.1 0.0 3.8 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 PVD24009.1 - 4.1e-05 23.8 1.2 1.7 8.9 0.0 3.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 PVD24009.1 - 5.3e-05 22.8 0.3 0.15 11.5 0.0 3.6 3 1 0 3 3 3 1 Ferrous iron transport protein B AAA_18 PF13238.6 PVD24009.1 - 5.9e-05 23.6 3.4 1.5 9.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 PVD24009.1 - 7.7e-05 23.0 0.5 8.4 6.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 PVD24009.1 - 0.00012 22.6 0.0 4.9 7.5 0.0 4.0 3 1 0 3 3 3 1 AAA ATPase domain G-alpha PF00503.20 PVD24009.1 - 0.00018 20.8 1.7 0.3 10.2 0.0 3.8 4 0 0 4 4 4 1 G-protein alpha subunit AAA_33 PF13671.6 PVD24009.1 - 0.00066 19.9 0.1 7 6.8 0.0 4.2 4 1 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 PVD24009.1 - 0.0008 19.2 0.5 11 5.7 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 PVD24009.1 - 0.0017 17.9 2.2 2.3 7.6 0.1 3.4 3 0 0 3 3 3 1 Poxvirus A32 protein T2SSE PF00437.20 PVD24009.1 - 0.004 16.2 0.9 1.7 7.6 0.1 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein CobU PF02283.16 PVD24009.1 - 0.0085 15.7 3.2 1.3 8.6 0.1 4.1 5 0 0 5 5 5 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF815 PF05673.13 PVD24009.1 - 0.013 14.7 0.4 2.6 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 PVD24009.1 - 0.015 15.0 0.3 28 4.3 0.0 3.6 3 0 0 3 3 3 0 Guanylate kinase AAA_7 PF12775.7 PVD24009.1 - 0.019 14.5 0.4 3.6 7.1 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Hpr_kinase_C PF07475.12 PVD24009.1 - 0.063 12.8 0.2 34 3.9 0.0 3.3 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Arf PF00025.21 PVD24009.1 - 0.064 12.7 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family DctP PF03480.13 PVD24009.1 - 0.092 12.1 0.2 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Sigma54_activat PF00158.26 PVD24009.1 - 0.099 12.3 0.3 38 3.9 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain CPT PF07931.12 PVD24009.1 - 0.22 11.3 3.0 16 5.3 0.1 3.3 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 PVD24009.1 - 0.3 11.1 1.9 13 5.8 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_28 PF13521.6 PVD24009.1 - 0.36 11.1 5.6 10 6.3 0.0 5.0 6 1 1 7 7 6 0 AAA domain Gtr1_RagA PF04670.12 PVD24009.1 - 0.65 9.3 4.7 16 4.7 0.1 3.5 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region SMC_N PF02463.19 PVD24009.1 - 1.1 8.7 2.8 30 4.0 0.0 3.6 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AIG1 PF04548.16 PVD24010.1 - 8e-47 159.3 2.8 1.4e-26 93.2 0.0 3.0 3 0 0 3 3 3 3 AIG1 family MMR_HSR1 PF01926.23 PVD24010.1 - 8.5e-11 41.9 0.2 6.9e-08 32.6 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD24010.1 - 5.2e-05 22.9 0.1 0.074 12.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD24010.1 - 0.00024 21.2 0.8 0.49 10.4 0.1 2.9 3 0 0 3 3 3 2 Dynamin family AAA_24 PF13479.6 PVD24010.1 - 0.0012 18.6 0.4 0.19 11.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 PVD24010.1 - 0.0056 16.1 1.1 0.067 12.5 0.1 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 PVD24010.1 - 0.007 15.9 0.5 0.018 14.5 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 PVD24010.1 - 0.018 14.1 0.2 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 PVD24010.1 - 0.019 14.4 0.3 0.38 10.1 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PVD24010.1 - 0.041 13.8 0.5 0.1 12.5 0.5 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 PVD24010.1 - 0.043 12.7 0.3 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.18 PVD24010.1 - 0.045 13.0 1.8 0.059 12.6 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 PVD24010.1 - 0.074 13.6 5.0 3 8.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 PVD24010.1 - 0.087 12.9 0.4 1.5 8.9 0.0 2.8 2 1 1 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 PVD24010.1 - 0.087 13.3 4.0 0.92 10.0 0.6 3.1 3 1 0 3 3 3 0 ABC transporter Sigma54_activat PF00158.26 PVD24010.1 - 0.099 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 PVD24010.1 - 0.14 12.5 0.2 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PVD24010.1 - 0.16 12.4 0.8 2.7 8.3 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 PVD24010.1 - 0.25 10.9 1.9 0.59 9.6 0.1 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF3886 PF13025.6 PVD24010.1 - 1 9.6 6.0 15 5.8 0.2 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF3886) AIG1 PF04548.16 PVD24011.1 - 8.6e-15 54.6 3.3 4.9e-08 32.6 1.9 2.7 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD24011.1 - 5.3e-07 29.7 0.4 0.016 15.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24011.1 - 1.2e-06 28.5 0.9 0.017 15.0 0.5 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PVD24011.1 - 1.6e-05 24.6 0.3 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Septin PF00735.18 PVD24011.1 - 3.6e-05 23.2 0.3 0.037 13.3 0.2 2.5 2 0 0 2 2 2 2 Septin AAA_22 PF13401.6 PVD24011.1 - 4.9e-05 23.6 0.0 0.14 12.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 PVD24011.1 - 4.9e-05 23.9 8.8 0.045 14.3 0.1 3.9 4 1 0 4 4 3 2 ABC transporter AAA_18 PF13238.6 PVD24011.1 - 5.2e-05 23.8 1.8 0.23 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.18 PVD24011.1 - 0.00024 20.6 1.8 0.23 10.8 0.0 2.6 2 1 1 3 3 3 2 FtsK/SpoIIIE family Sigma54_activat PF00158.26 PVD24011.1 - 0.00038 20.2 0.6 0.87 9.3 0.0 3.1 2 1 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 PVD24011.1 - 0.001 19.4 0.2 0.96 9.9 0.1 3.2 3 0 0 3 3 3 1 RNA helicase G-alpha PF00503.20 PVD24011.1 - 0.0015 17.8 0.1 0.2 10.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 PVD24011.1 - 0.0017 18.6 0.8 0.26 11.5 0.3 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 PVD24011.1 - 0.0017 18.3 0.1 0.54 10.2 0.1 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 PVD24011.1 - 0.0017 18.6 0.1 0.22 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PVD24011.1 - 0.0045 16.7 0.2 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PVD24011.1 - 0.0082 16.2 6.0 0.44 10.6 0.1 3.1 4 0 0 4 4 2 2 Dynamin family AAA_16 PF13191.6 PVD24011.1 - 0.0088 16.4 0.2 3.6 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 PVD24011.1 - 0.01 15.6 0.6 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 PVD24011.1 - 0.016 14.3 1.9 2.8 6.9 0.2 2.5 1 1 1 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 PVD24011.1 - 0.017 14.9 0.2 2.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 PVD24011.1 - 0.017 14.6 0.2 0.55 9.6 0.2 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ig_2 PF13895.6 PVD24011.1 - 0.022 15.1 3.8 0.86 10.0 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Hpr_kinase_C PF07475.12 PVD24011.1 - 0.028 14.0 2.3 0.56 9.7 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_7 PF12775.7 PVD24011.1 - 0.03 13.8 1.2 1.4 8.4 0.1 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 PVD24011.1 - 0.034 13.8 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_33 PF13671.6 PVD24011.1 - 0.046 13.9 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 PVD24011.1 - 0.073 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Ras PF00071.22 PVD24011.1 - 0.073 12.7 0.2 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 PVD24011.1 - 0.077 12.0 0.3 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.6 PVD24011.1 - 0.12 12.1 1.5 4.9 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ig_3 PF13927.6 PVD24011.1 - 0.15 12.7 1.2 0.86 10.2 0.8 2.4 1 1 1 2 2 2 0 Immunoglobulin domain DUF3377 PF11857.8 PVD24011.1 - 0.24 11.3 1.8 0.61 10.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF87 PF01935.17 PVD24011.1 - 0.29 11.2 5.7 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Pox_A32 PF04665.12 PVD24011.1 - 1 8.8 4.4 11 5.4 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein NACHT PF05729.12 PVD24011.1 - 1.9 8.4 3.7 9.9 6.0 0.3 2.3 2 0 0 2 2 2 0 NACHT domain I-set PF07679.16 PVD24012.1 - 1.1e-14 54.2 0.2 0.028 14.5 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain V-set PF07686.17 PVD24012.1 - 3.4e-11 43.3 12.1 0.014 15.6 0.1 5.2 5 1 0 5 5 5 4 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD24012.1 - 3.5e-11 43.6 19.8 0.22 12.1 0.4 6.8 6 1 1 7 7 7 5 Immunoglobulin domain Ig_4 PF16680.5 PVD24012.1 - 2.9e-05 24.2 10.4 1.7 8.9 1.2 5.6 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.6 PVD24012.1 - 3.5e-05 24.1 19.7 1.8 8.9 0.5 6.3 6 3 0 6 6 6 4 Immunoglobulin domain ig PF00047.25 PVD24012.1 - 0.00058 20.0 22.3 0.9 9.8 0.1 7.1 7 2 0 8 8 8 3 Immunoglobulin domain V-set_2 PF15910.5 PVD24012.1 - 0.0026 17.8 1.7 4.1 7.5 0.0 3.8 3 1 0 3 3 3 2 ICOS V-set domain C2-set PF05790.15 PVD24012.1 - 0.008 16.3 5.1 2.5 8.4 0.6 4.2 5 0 0 5 5 5 2 Immunoglobulin C2-set domain AIG1 PF04548.16 PVD24013.1 - 5.7e-10 38.9 1.5 0.00023 20.5 0.3 3.5 2 1 1 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 PVD24013.1 - 3.2e-05 24.0 0.0 0.00033 20.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24013.1 - 0.012 15.6 0.1 0.77 9.8 0.1 2.4 1 1 0 1 1 1 0 Dynamin family PAS_8 PF13188.7 PVD24013.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain AIG1 PF04548.16 PVD24014.1 - 4.5e-33 114.4 0.2 5.5e-33 114.1 0.2 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24014.1 - 5.7e-09 36.1 0.2 8.4e-09 35.5 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24014.1 - 0.00014 21.8 0.3 0.00024 21.1 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 PVD24014.1 - 0.00064 19.2 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 PVD24014.1 - 0.0007 20.1 0.4 0.00082 19.9 0.4 1.4 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 PVD24014.1 - 0.0021 18.1 1.9 0.0043 17.1 0.9 1.8 1 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 PVD24014.1 - 0.036 13.6 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Guanylate_kin PF00625.21 PVD24014.1 - 0.036 13.7 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase DUF87 PF01935.17 PVD24014.1 - 0.046 13.8 0.2 0.095 12.8 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Septin PF00735.18 PVD24014.1 - 0.047 13.0 0.3 0.087 12.1 0.3 1.4 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.26 PVD24014.1 - 0.058 13.1 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 PVD24014.1 - 0.086 13.2 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 PVD24014.1 - 0.089 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 PVD24014.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 PVD24014.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PVD24014.1 - 0.27 11.7 0.7 0.68 10.4 0.7 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 PVD24015.1 - 2.3e-07 30.4 1.1 3.3e-07 29.9 1.1 1.2 1 0 0 1 1 1 1 AIG1 family TraG_N PF07916.11 PVD24015.1 - 0.033 13.1 0.2 0.034 13.0 0.2 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AIG1 PF04548.16 PVD24016.1 - 3.8e-65 219.2 5.1 6.8e-24 84.4 0.0 4.3 3 1 1 4 4 4 4 AIG1 family MMR_HSR1 PF01926.23 PVD24016.1 - 9.4e-26 90.1 0.3 4e-08 33.3 0.0 3.4 3 1 0 3 3 3 3 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24016.1 - 7e-14 52.2 9.7 5.4e-05 23.3 0.1 4.9 5 0 0 5 5 5 4 Dynamin family RsgA_GTPase PF03193.16 PVD24016.1 - 4.9e-10 39.6 3.3 0.0021 18.0 0.0 3.5 3 0 0 3 3 3 3 RsgA GTPase ABC_tran PF00005.27 PVD24016.1 - 2e-09 38.1 0.9 0.074 13.6 0.3 3.7 3 1 0 3 3 3 3 ABC transporter Roc PF08477.13 PVD24016.1 - 4.7e-08 33.3 1.1 0.066 13.4 0.0 3.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 PVD24016.1 - 2.6e-07 30.3 0.3 0.02 14.4 0.0 3.3 3 0 0 3 3 3 2 Ferrous iron transport protein B SRPRB PF09439.10 PVD24016.1 - 2.9e-07 30.1 1.3 0.59 9.5 0.0 3.6 3 0 0 3 3 3 3 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 PVD24016.1 - 3.7e-07 29.8 1.1 1.1 9.0 0.0 3.6 3 0 0 3 3 3 3 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 PVD24016.1 - 9.5e-07 28.4 0.1 0.17 11.2 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 PVD24016.1 - 2.6e-06 27.7 0.9 1.4 9.3 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.6 PVD24016.1 - 8.5e-06 26.1 2.1 0.2 11.9 0.2 3.7 3 1 0 3 3 3 1 AAA domain Septin PF00735.18 PVD24016.1 - 1.1e-05 24.8 3.6 0.7 9.1 0.1 4.3 3 1 1 4 4 4 1 Septin AAA_18 PF13238.6 PVD24016.1 - 1.5e-05 25.6 2.9 1 9.9 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_24 PF13479.6 PVD24016.1 - 1.6e-05 24.7 0.2 3.9 7.1 0.0 3.8 3 0 0 3 3 3 2 AAA domain Gtr1_RagA PF04670.12 PVD24016.1 - 2.7e-05 23.6 5.4 0.046 13.1 0.2 3.5 3 1 0 3 3 3 1 Gtr1/RagA G protein conserved region T2SSE PF00437.20 PVD24016.1 - 5.4e-05 22.4 0.2 0.16 11.0 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein G-alpha PF00503.20 PVD24016.1 - 5.4e-05 22.5 3.1 0.15 11.2 0.0 3.8 3 1 0 3 3 3 1 G-protein alpha subunit AAA_16 PF13191.6 PVD24016.1 - 0.00014 22.3 0.6 3.2 8.1 0.3 3.8 3 1 0 3 3 3 2 AAA ATPase domain PduV-EutP PF10662.9 PVD24016.1 - 0.00024 20.8 1.1 3 7.6 0.0 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 PVD24016.1 - 0.00072 19.1 0.8 2.5 7.5 0.0 3.4 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_7 PF12775.7 PVD24016.1 - 0.0016 18.0 1.7 1.7 8.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region Arf PF00025.21 PVD24016.1 - 0.0021 17.5 0.5 1.2 8.6 0.0 3.4 3 0 0 3 3 3 1 ADP-ribosylation factor family Sigma54_activat PF00158.26 PVD24016.1 - 0.0029 17.3 0.2 4.4 7.0 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain Guanylate_kin PF00625.21 PVD24016.1 - 0.0041 16.8 0.4 24 4.5 0.0 3.7 3 0 0 3 3 3 0 Guanylate kinase Ras PF00071.22 PVD24016.1 - 0.0072 15.9 1.2 2.1 7.9 0.0 3.5 4 0 0 4 4 3 1 Ras family CobU PF02283.16 PVD24016.1 - 0.018 14.6 3.2 0.64 9.6 0.1 3.2 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NTP_transferase PF00483.23 PVD24016.1 - 0.019 14.5 0.3 0.043 13.4 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase PRANC PF09372.10 PVD24016.1 - 0.052 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PRANC domain AAA_28 PF13521.6 PVD24016.1 - 0.055 13.7 1.9 10 6.3 0.0 4.3 5 0 0 5 5 5 0 AAA domain RNase_P_p30 PF01876.16 PVD24016.1 - 0.079 12.4 0.0 4.8 6.6 0.1 2.5 1 1 1 2 2 2 0 RNase P subunit p30 DUF815 PF05673.13 PVD24016.1 - 0.095 11.8 0.2 2.9 7.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 PVD24016.1 - 0.14 12.3 2.7 29 4.8 0.0 4.2 3 1 1 4 4 4 0 AAA domain CLP1_P PF16575.5 PVD24016.1 - 1 9.1 6.0 30 4.4 0.2 3.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CPT PF07931.12 PVD24016.1 - 1.7 8.5 6.2 10 5.9 0.2 3.2 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AIG1 PF04548.16 PVD24017.1 - 1.6e-30 106.0 0.0 1.8e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24017.1 - 5.5e-09 36.1 0.1 1.7e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24017.1 - 7.5e-05 22.7 1.3 9.1e-05 22.4 0.2 1.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD24017.1 - 0.00026 21.5 0.0 0.0004 20.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 PVD24017.1 - 0.00064 20.3 0.7 0.056 13.9 0.3 2.2 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 PVD24017.1 - 0.0017 18.4 0.6 0.0031 17.6 0.6 1.8 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 PVD24017.1 - 0.0055 16.2 1.0 0.013 15.0 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 PVD24017.1 - 0.013 15.8 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 PVD24017.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 PVD24017.1 - 0.063 13.0 0.2 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 PVD24017.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 PVD24017.1 - 0.17 11.4 0.8 2.3 7.7 0.2 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PVD24018.1 - 1.8e-30 105.9 0.4 3e-30 105.1 0.4 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24018.1 - 7.5e-09 35.7 0.4 1.4e-08 34.8 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24018.1 - 0.00021 21.4 2.7 0.00092 19.3 2.7 2.4 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 PVD24018.1 - 0.00084 19.3 0.5 0.00084 19.3 0.5 1.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD24018.1 - 0.0025 18.3 2.2 0.0049 17.4 2.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.7 PVD24018.1 - 0.005 15.8 0.5 0.0067 15.4 0.5 1.3 1 0 0 1 1 1 1 AAA-like domain FeoB_N PF02421.18 PVD24018.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 PVD24018.1 - 0.03 13.6 1.9 0.034 13.4 0.2 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 PVD24018.1 - 0.083 12.6 0.1 0.33 10.7 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PVD24018.1 - 0.13 12.6 0.7 6 7.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 PVD24018.1 - 0.16 11.3 1.1 1.3 8.3 0.2 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.6 PVD24018.1 - 4.6 7.7 11.4 17 5.8 11.4 1.8 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 PVD24019.1 - 2.3e-24 85.9 0.1 2.6e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24019.1 - 5.8e-07 29.6 0.1 9e-07 29.0 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24019.1 - 0.0002 21.3 0.0 0.00067 19.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD24019.1 - 0.0057 17.2 0.2 0.0064 17.0 0.2 1.3 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 PVD24019.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 PVD24019.1 - 0.049 13.3 0.1 0.26 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 PVD24019.1 - 0.057 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 PVD24019.1 - 0.15 12.1 2.8 1.8 8.6 2.8 2.4 1 1 0 1 1 1 0 Dynamin family AIG1 PF04548.16 PVD24020.1 - 7.1e-33 113.7 0.0 9.1e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD24020.1 - 1.6e-08 34.6 0.1 3.8e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24020.1 - 0.00017 21.5 0.8 0.00037 20.4 0.2 1.8 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD24020.1 - 0.00079 19.9 0.0 0.0013 19.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 PVD24020.1 - 0.0032 17.5 0.4 0.0078 16.3 0.4 1.6 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 PVD24020.1 - 0.012 15.0 0.1 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 PVD24020.1 - 0.012 15.3 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 PVD24020.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 PVD24020.1 - 0.037 14.4 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF2157 PF09925.9 PVD24020.1 - 0.038 13.8 0.6 0.054 13.3 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) AAA_23 PF13476.6 PVD24020.1 - 0.15 12.6 2.2 0.33 11.4 2.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD24020.1 - 0.2 11.2 0.1 0.37 10.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 PVD24021.1 - 1.6e-84 282.5 4.7 1.8e-26 92.8 0.0 4.2 3 1 1 4 4 4 4 AIG1 family MMR_HSR1 PF01926.23 PVD24021.1 - 2e-26 92.3 0.7 9.3e-08 32.2 0.1 3.5 3 0 0 3 3 3 3 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24021.1 - 1.3e-11 44.8 16.0 0.0015 18.6 0.0 5.5 4 2 1 5 5 5 3 Dynamin family RsgA_GTPase PF03193.16 PVD24021.1 - 4.3e-11 43.0 7.1 0.0053 16.7 0.1 3.7 3 0 0 3 3 3 3 RsgA GTPase FtsK_SpoIIIE PF01580.18 PVD24021.1 - 3.9e-08 32.9 0.6 0.26 10.6 0.0 3.7 3 0 0 3 3 3 3 FtsK/SpoIIIE family FeoB_N PF02421.18 PVD24021.1 - 6.2e-08 32.3 0.4 0.0038 16.8 0.1 3.3 3 0 0 3 3 3 2 Ferrous iron transport protein B AAA_29 PF13555.6 PVD24021.1 - 2.3e-07 30.4 1.2 0.74 9.6 0.1 3.5 3 0 0 3 3 3 3 P-loop containing region of AAA domain Septin PF00735.18 PVD24021.1 - 3.2e-07 29.9 5.2 0.083 12.2 0.1 4.2 3 1 1 4 4 4 3 Septin ABC_tran PF00005.27 PVD24021.1 - 3.6e-07 30.8 2.3 0.17 12.4 1.1 3.7 3 1 0 3 3 3 2 ABC transporter SRPRB PF09439.10 PVD24021.1 - 2.4e-06 27.1 2.1 0.69 9.3 0.1 3.5 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PVD24021.1 - 4.4e-06 27.0 1.0 0.38 11.0 0.3 4.1 3 1 0 3 3 3 2 AAA domain Roc PF08477.13 PVD24021.1 - 1.3e-05 25.4 7.2 0.51 10.6 0.1 4.5 4 1 1 5 5 5 3 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 PVD24021.1 - 2.9e-05 24.4 0.8 2.5 8.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase Gtr1_RagA PF04670.12 PVD24021.1 - 7.4e-05 22.2 0.1 0.027 13.8 0.0 3.4 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 PVD24021.1 - 8.7e-05 22.3 6.4 0.77 9.4 0.2 4.1 4 1 0 5 5 5 2 AAA domain AAA_18 PF13238.6 PVD24021.1 - 0.00034 21.2 6.5 0.6 10.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 PVD24021.1 - 0.00059 20.3 0.9 15 5.9 0.0 4.7 5 1 0 5 5 5 0 AAA ATPase domain Pox_A32 PF04665.12 PVD24021.1 - 0.00078 19.0 1.1 2.1 7.7 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A32 protein G-alpha PF00503.20 PVD24021.1 - 0.00099 18.4 6.1 0.1 11.7 0.0 4.0 3 1 0 3 3 3 1 G-protein alpha subunit T2SSE PF00437.20 PVD24021.1 - 0.0027 16.8 0.4 1.7 7.6 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein IIGP PF05049.13 PVD24021.1 - 0.0032 16.6 0.6 0.17 10.9 0.1 2.9 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 PVD24021.1 - 0.0038 17.0 0.7 9.5 6.0 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 PVD24021.1 - 0.0066 15.9 0.8 2.5 7.5 0.0 3.7 3 0 0 3 3 3 1 ADP-ribosylation factor family Guanylate_kin PF00625.21 PVD24021.1 - 0.012 15.3 1.1 14 5.4 0.1 3.6 3 0 0 3 3 3 0 Guanylate kinase CobU PF02283.16 PVD24021.1 - 0.013 15.0 4.2 1.1 8.8 0.0 4.0 5 1 0 5 5 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_33 PF13671.6 PVD24021.1 - 0.018 15.2 1.7 5 7.3 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 PVD24021.1 - 0.046 13.2 1.8 2.1 7.8 0.1 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD24021.1 - 0.068 12.9 0.1 3.3 7.4 0.0 3.4 3 1 1 4 4 4 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.12 PVD24021.1 - 0.079 12.5 1.2 22 4.5 0.0 3.5 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain Tcf25 PF04910.14 PVD24021.1 - 0.14 11.2 0.4 0.23 10.5 0.4 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 AAA_28 PF13521.6 PVD24021.1 - 2.3 8.5 5.5 8.6 6.6 0.0 4.2 6 0 0 6 6 5 0 AAA domain AIG1 PF04548.16 PVD24022.1 - 2.3e-63 213.3 0.0 4.2e-50 170.0 0.0 2.0 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD24022.1 - 4.3e-09 36.5 0.0 1.4e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24022.1 - 7.2e-06 26.2 1.8 0.058 13.4 1.1 2.8 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD24022.1 - 1.7e-05 24.8 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PVD24022.1 - 0.0034 17.9 0.1 0.0093 16.5 0.1 1.7 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 PVD24022.1 - 0.051 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Hema_HEFG PF02710.14 PVD24022.1 - 0.084 13.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein DUF2093 PF09866.9 PVD24022.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) PduV-EutP PF10662.9 PVD24022.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GerPC PF10737.9 PVD24022.1 - 0.24 11.5 1.3 0.48 10.5 1.3 1.4 1 0 0 1 1 1 0 Spore germination protein GerPC AIG1 PF04548.16 PVD24023.1 - 1.2e-24 86.8 0.5 2.1e-16 59.9 0.1 3.3 3 0 0 3 3 3 2 AIG1 family ABC_tran PF00005.27 PVD24023.1 - 0.093 13.2 0.0 0.23 12.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter HAD_SAK_2 PF18143.1 PVD24023.1 - 0.15 12.4 0.1 0.15 12.4 0.1 3.0 2 1 1 3 3 3 0 HAD domain in Swiss Army Knife RNA repair proteins Ldl_recept_a PF00057.18 PVD24024.1 - 0.00038 20.6 1.1 0.00038 20.6 1.1 4.0 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD24024.1 - 0.003 18.3 0.0 0.0072 17.0 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain Prok-RING_2 PF14445.6 PVD24024.1 - 0.14 12.4 3.1 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Neur_chan_LBD PF02931.23 PVD24025.1 - 2.2e-41 141.7 3.2 6.4e-21 74.8 0.2 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD24025.1 - 1.9e-18 67.4 12.4 1.3e-10 41.8 0.0 2.8 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region EB PF01683.18 PVD24025.1 - 1.2e-05 25.4 34.6 0.0024 18.1 4.2 4.4 3 1 1 4 4 4 3 EB module MNSV_P7B PF06692.11 PVD24025.1 - 0.14 12.2 1.6 2 8.5 0.1 2.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF4144 PF13642.6 PVD24025.1 - 3.5 8.3 5.7 3.6 8.2 0.4 2.9 2 1 0 3 3 3 0 protein structure with unknown function Neur_chan_LBD PF02931.23 PVD24026.1 - 1.6e-42 145.4 5.2 2.8e-42 144.6 5.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD24026.1 - 3e-10 40.6 12.3 1e-09 38.8 8.4 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD24027.1 - 4.9e-25 88.3 0.0 6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1180 PF06679.12 PVD24028.1 - 0.1 13.0 3.3 0.12 12.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PRIMA1 PF16101.5 PVD24029.1 - 0.26 11.3 12.2 0.41 10.7 12.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD24029.1 - 3.3 7.1 9.0 5.1 6.5 9.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EB PF01683.18 PVD24030.1 - 4e-09 36.6 70.8 6.5e-05 23.1 13.9 6.4 3 2 3 6 6 6 4 EB module SOG2 PF10428.9 PVD24031.1 - 7.4 5.7 12.0 8.5 5.4 12.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 PVD24032.1 - 6.2e-13 48.4 2.5 9.1e-13 47.9 0.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 PVD24032.1 - 4.5e-07 29.6 3.5 1.1e-06 28.4 0.1 2.8 2 1 0 2 2 2 1 F-box domain F-box_5 PF18511.1 PVD24032.1 - 0.085 12.4 0.5 0.25 10.9 0.5 1.8 1 0 0 1 1 1 0 F-box RVT_1 PF00078.27 PVD24033.1 - 0.00024 20.7 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5383 PF17355.2 PVD24034.1 - 0.19 12.1 0.1 0.19 12.1 0.1 5.9 4 2 1 5 5 5 0 Family of unknown function (DUF5383) PHR PF08005.12 PVD24034.1 - 0.95 10.1 4.5 22 5.7 2.1 3.4 3 0 0 3 3 3 0 PHR domain UPF0182 PF03699.13 PVD24034.1 - 2.9 5.9 4.4 5.2 5.1 4.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) zf-RING_2 PF13639.6 PVD24035.1 - 1.7e-09 37.8 7.6 1.7e-09 37.8 7.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD24035.1 - 3.1e-09 36.7 5.4 3.6e-09 36.5 3.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD24035.1 - 6.1e-09 35.6 5.4 6.1e-09 35.6 5.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD24035.1 - 5.1e-07 29.4 3.5 5.1e-07 29.4 3.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD24035.1 - 3.5e-06 27.1 6.9 7.7e-06 26.0 6.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD24035.1 - 1.3e-05 24.9 7.1 1.3e-05 24.9 7.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD24035.1 - 1.4e-05 24.8 5.4 1.4e-05 24.8 5.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD24035.1 - 5.4e-05 23.1 5.9 5.4e-05 23.1 5.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD24035.1 - 0.0086 16.1 3.2 0.0086 16.1 3.2 2.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PVD24035.1 - 0.021 15.1 5.6 0.24 11.7 5.6 2.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD24035.1 - 0.024 14.4 0.7 0.088 12.6 0.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger DUF1644 PF07800.12 PVD24035.1 - 0.096 12.8 1.4 0.44 10.6 1.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) NOB1_Zn_bind PF08772.11 PVD24035.1 - 0.31 11.2 0.2 0.31 11.2 0.2 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-TFIIIC PF12660.7 PVD24035.1 - 1.2 9.1 4.9 2.9 7.9 4.5 1.8 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_10 PF16685.5 PVD24035.1 - 2.8 8.1 7.6 1.4 9.1 3.0 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 Epiglycanin_TR PF05647.11 PVD24036.1 - 0.0013 18.6 24.6 0.0013 18.6 24.6 5.1 1 1 5 6 6 6 3 Tandem-repeating region of mucin, epiglycanin-like LEP503 PF15221.6 PVD24036.1 - 0.15 12.4 0.2 6.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 PrcB_C PF14343.6 PVD24036.1 - 8.9 6.5 10.4 19 5.5 0.9 3.3 1 1 3 4 4 4 0 PrcB C-terminal TFIIA PF03153.13 PVD24038.1 - 9.3 6.1 22.5 0.61 10.0 16.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_1_7 PF13843.6 PVD24039.1 - 2.2e-11 43.7 0.1 2.9e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 EB PF01683.18 PVD24040.1 - 1.7e-11 44.2 38.3 1e-05 25.7 9.0 4.3 4 0 0 4 4 4 3 EB module cEGF PF12662.7 PVD24040.1 - 0.13 12.2 23.7 0.091 12.7 3.4 3.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like EB PF01683.18 PVD24041.1 - 7.9e-11 42.1 104.8 0.015 15.6 11.2 8.4 2 2 6 8 8 8 8 EB module cEGF PF12662.7 PVD24041.1 - 2.2 8.3 30.4 1.6 8.7 0.8 5.9 6 0 0 6 6 6 0 Complement Clr-like EGF-like F-box-like PF12937.7 PVD24042.1 - 3e-09 36.6 0.4 7.9e-09 35.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD24042.1 - 7.7e-07 28.8 0.1 1.7e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD24042.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 F-box Trypsin PF00089.26 PVD24043.1 - 2.8e-29 102.5 0.0 2.8e-29 102.5 0.0 3.6 3 2 0 3 3 3 1 Trypsin EB PF01683.18 PVD24043.1 - 0.02 15.2 79.4 0.23 11.8 9.8 6.7 1 1 5 6 6 6 0 EB module Mso1_Sec1_bdg PF14475.6 PVD24043.1 - 0.69 9.5 2.8 30 4.3 0.1 3.2 3 0 0 3 3 3 0 Sec1-binding region of Mso1 zf-RING_2 PF13639.6 PVD24044.1 - 2.2e-09 37.5 7.5 2.2e-09 37.5 7.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD24044.1 - 2e-08 34.1 8.5 6e-08 32.6 7.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD24044.1 - 4.4e-08 32.9 5.9 4.4e-08 32.9 5.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD24044.1 - 1.1e-06 28.4 5.2 1.1e-06 28.4 5.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD24044.1 - 4.2e-06 26.8 7.4 1.1e-05 25.5 7.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD24044.1 - 5.4e-06 26.1 8.0 5.4e-06 26.1 8.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD24044.1 - 0.00033 20.4 7.4 0.00033 20.4 7.4 2.5 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD24044.1 - 0.00048 20.0 6.5 0.0015 18.4 6.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD24044.1 - 0.0025 17.8 3.7 0.0079 16.2 3.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CortBP2 PF09727.9 PVD24044.1 - 0.0053 16.7 4.7 0.0053 16.7 4.7 2.1 1 1 1 2 2 2 1 Cortactin-binding protein-2 zf-rbx1 PF12678.7 PVD24044.1 - 0.036 14.4 5.9 0.2 12.0 5.9 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 PVD24044.1 - 0.076 12.9 1.5 3.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PVD24044.1 - 2 8.3 5.2 8.3 6.3 5.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Med19 PF10278.9 PVD24044.1 - 3.8 7.4 11.5 6.9 6.6 11.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Borrelia_P83 PF05262.11 PVD24044.1 - 7.7 4.9 9.7 12 4.3 9.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein EB PF01683.18 PVD24045.1 - 1.9e-09 37.7 41.6 2.7e-05 24.4 7.0 3.2 2 1 1 3 3 3 3 EB module EGF_3 PF12947.7 PVD24045.1 - 0.0061 16.7 47.7 0.088 13.0 10.8 3.4 3 0 0 3 3 3 3 EGF domain cEGF PF12662.7 PVD24045.1 - 0.12 12.3 23.9 0.3 11.1 2.2 4.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 PVD24045.1 - 0.19 11.8 24.2 2.6 8.2 4.6 3.9 3 1 0 3 3 3 0 MSP1 EGF domain 1 Trypsin PF00089.26 PVD24046.1 - 4e-33 115.1 0.5 1e-31 110.5 0.0 2.7 2 1 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PVD24046.1 - 1.6e-05 25.8 0.0 4.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD24046.1 - 0.13 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sod_Cu PF00080.20 PVD24047.1 - 2e-34 118.8 3.2 3.2e-34 118.1 3.2 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Carn_acyltransf PF00755.20 PVD24049.1 - 1.7e-169 565.2 1.9 3.7e-127 425.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase EGF PF00008.27 PVD24050.1 - 1.5e-89 293.7 254.8 9.8e-09 35.4 7.2 20.4 20 1 0 20 20 20 18 EGF-like domain EGF_CA PF07645.15 PVD24050.1 - 1.7e-70 232.9 267.4 3.5e-07 30.3 5.7 21.6 14 5 8 22 22 22 16 Calcium-binding EGF domain hEGF PF12661.7 PVD24050.1 - 1.2e-55 184.3 254.0 4.1e-08 33.5 5.2 21.6 22 1 0 22 22 22 18 Human growth factor-like EGF EGF_2 PF07974.13 PVD24050.1 - 2.8e-24 85.1 301.3 0.00022 21.5 5.4 20.0 20 0 0 20 20 20 15 EGF-like domain EGF_3 PF12947.7 PVD24050.1 - 1.6e-17 63.4 207.3 0.0026 17.9 6.9 19.2 16 2 2 18 18 18 16 EGF domain DSL PF01414.19 PVD24050.1 - 9.1e-12 45.1 2.3 9.1e-12 45.1 2.3 12.9 11 2 2 13 13 13 1 Delta serrate ligand cEGF PF12662.7 PVD24050.1 - 1.7e-05 24.6 8.6 0.00012 21.9 1.7 18.9 20 2 0 20 20 20 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD24050.1 - 2.8 8.3 240.7 0.066 13.5 7.0 20.2 7 3 13 20 20 20 0 Coagulation Factor Xa inhibitory site zf-H2C2_2 PF13465.6 PVD24051.1 - 2.7e-25 87.6 45.8 2.9e-09 36.9 0.7 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD24051.1 - 3.1e-22 77.7 52.2 8.6e-07 29.1 3.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD24051.1 - 1.2e-19 69.3 49.8 0.0006 20.4 2.9 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD24051.1 - 2.1e-10 40.6 28.4 0.0039 17.4 0.6 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD24051.1 - 7.8e-07 28.9 41.3 0.0036 17.3 2.9 6.9 6 1 0 6 6 6 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PVD24051.1 - 1.1e-05 25.2 25.6 0.023 14.6 0.6 6.4 6 0 0 6 6 6 3 zinc-finger of a C2HC-type zf-met PF12874.7 PVD24051.1 - 2.3e-05 24.6 34.2 0.77 10.2 1.7 6.6 6 0 0 6 6 6 3 Zinc-finger of C2H2 type SET PF00856.28 PVD24051.1 - 3.3e-05 24.3 0.0 5.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-C2H2_11 PF16622.5 PVD24051.1 - 0.00024 20.8 33.3 0.0032 17.2 2.6 6.2 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PVD24051.1 - 0.0016 18.7 31.2 0.18 12.2 2.6 5.8 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 PVD24051.1 - 0.0022 18.2 24.7 1.4 9.3 8.4 3.7 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 PVD24051.1 - 0.0072 17.1 21.6 0.27 12.0 1.3 3.5 1 1 2 3 3 3 2 zinc-ribbon family zf-BED PF02892.15 PVD24051.1 - 0.015 15.3 39.5 2.6 8.1 2.1 6.3 1 1 5 6 6 6 0 BED zinc finger Zn-ribbon_8 PF09723.10 PVD24051.1 - 0.027 14.6 23.3 1.1 9.5 1.6 4.8 3 2 1 4 4 4 0 Zinc ribbon domain HNH_5 PF14279.6 PVD24051.1 - 0.073 12.9 17.4 6 6.8 0.1 5.6 5 1 0 5 5 5 0 HNH endonuclease PH_3 PF14593.6 PVD24051.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 1 0 PH domain DUF1835 PF08874.10 PVD24051.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) zf_UBZ PF18439.1 PVD24051.1 - 0.32 10.6 23.2 1.1 8.9 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger DUF2180 PF09947.9 PVD24051.1 - 0.4 10.7 5.8 8.5 6.4 0.0 3.4 2 1 1 4 4 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HE PF16278.5 PVD24051.1 - 1 9.9 33.2 1.1 9.7 3.0 6.0 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 PVD24051.1 - 1.4 9.0 28.6 13 6.0 0.3 6.6 7 0 0 7 7 7 0 XPA protein N-terminal DUF2256 PF10013.9 PVD24051.1 - 2.6 8.2 22.6 8.4 6.6 0.1 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 PVD24051.1 - 3.5 7.7 18.5 15 5.6 5.1 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sprouty PF05210.13 PVD24051.1 - 5.2 7.5 20.0 0.069 13.5 5.7 3.3 2 1 1 3 3 3 0 Sprouty protein (Spry) Zf_RING PF16744.5 PVD24051.1 - 5.7 7.1 21.2 8.5 6.6 0.3 5.6 2 1 4 6 6 6 0 KIAA1045 RING finger FYVE PF01363.21 PVD24051.1 - 6 7.1 35.0 47 4.2 11.0 4.5 1 1 1 2 2 2 0 FYVE zinc finger APT PF03440.14 PVD24053.1 - 0.09 12.7 0.2 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain Mfa1 PF17445.2 PVD24055.1 - 0.0061 16.6 0.4 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Mating factor A1 Endonuclease_7 PF02945.15 PVD24058.1 - 0.0087 16.0 0.4 2.9 7.9 0.2 2.5 2 0 0 2 2 2 2 Recombination endonuclease VII TMEM154 PF15102.6 PVD24058.1 - 0.024 14.5 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF4534 PF15049.6 PVD24058.1 - 0.03 14.1 0.9 0.068 12.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) 7TM_GPCR_Srd PF10317.9 PVD24058.1 - 0.036 13.3 1.7 2.4 7.3 0.7 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF4893 PF16233.5 PVD24058.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) ShK PF01549.24 PVD24059.1 - 3.2e-20 72.4 30.8 3.6e-10 40.2 11.5 3.0 2 0 0 2 2 2 2 ShK domain-like EphA2_TM PF14575.6 PVD24060.1 - 0.018 15.9 0.0 0.048 14.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 PVD24061.1 - 0.2 12.3 7.3 5.6 7.6 0.0 3.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Y_phosphatase PF00102.27 PVD24062.1 - 9.4e-19 67.9 3.4 7.1e-07 29.0 0.2 3.2 2 1 1 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 PVD24063.1 - 3.9e-52 177.1 0.8 5.1e-52 176.8 0.8 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF5385 PF17359.2 PVD24064.1 - 0.022 14.3 0.0 7.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) F5_F8_type_C PF00754.25 PVD24064.1 - 0.049 13.7 1.0 0.48 10.5 0.1 2.6 3 0 0 3 3 3 0 F5/8 type C domain SCIMP PF15050.6 PVD24064.1 - 0.066 13.7 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein Mito_fiss_reg PF05308.11 PVD24064.1 - 4.6 7.2 7.0 9.2 6.3 7.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator F5_F8_type_C PF00754.25 PVD24066.1 - 0.039 14.1 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 F5/8 type C domain Phage_Gp23 PF10669.9 PVD24066.1 - 0.048 14.0 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RhoGEF PF00621.20 PVD24067.1 - 1.3e-47 162.4 0.5 2.4e-47 161.5 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 PVD24067.1 - 4.6e-15 55.5 7.9 4.6e-15 55.5 7.9 2.2 3 0 0 3 3 3 1 FYVE zinc finger PH PF00169.29 PVD24067.1 - 5.2e-14 52.6 0.2 2.1e-10 41.1 0.1 3.0 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 PVD24067.1 - 0.032 14.7 1.3 0.4 11.1 1.3 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 PVD24067.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain T3SSipB PF16535.5 PVD24067.1 - 0.13 12.7 0.1 0.13 12.7 0.1 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB ADH_zinc_N PF00107.26 PVD24068.1 - 2.3e-28 98.8 0.4 8.6e-28 96.9 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD24068.1 - 4.6e-10 40.7 0.0 1.7e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase VGCC_alpha2 PF08473.11 PVD24069.1 - 1.4e-57 195.4 4.2 2.4e-57 194.7 4.2 1.3 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 PVD24069.1 - 7.4e-08 32.5 1.8 0.0015 18.4 0.0 2.5 2 1 0 2 2 2 2 Cache domain dCache_2 PF08269.11 PVD24069.1 - 0.039 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Cache domain VWA_N PF08399.11 PVD24070.1 - 1.7e-31 109.3 2.4 1.3e-30 106.4 0.6 2.4 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 PVD24070.1 - 9.6e-18 65.0 0.1 2e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD24070.1 - 9.9e-17 61.3 0.0 2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24070.1 - 1.3e-13 51.5 0.2 5.4e-13 49.5 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain SseB_C PF14581.6 PVD24070.1 - 0.044 13.9 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF2201 PF09967.9 PVD24070.1 - 0.15 12.2 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 VWA-like domain (DUF2201) M PF02370.16 PVD24070.1 - 0.3 11.8 2.7 0.82 10.4 2.7 1.7 1 0 0 1 1 1 0 M protein repeat Trypsin PF00089.26 PVD24071.1 - 2.1e-26 93.1 0.0 2.7e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD24071.1 - 0.0006 20.2 0.4 0.0013 19.1 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) TPR_1 PF00515.28 PVD24072.1 - 4.7e-10 38.9 0.0 0.052 13.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD24072.1 - 7.2e-08 32.0 0.4 0.069 13.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD24072.1 - 0.00053 19.8 1.2 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD24072.1 - 0.001 18.9 1.1 0.53 10.4 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD24072.1 - 0.0039 17.3 4.8 0.041 14.0 0.3 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD24072.1 - 0.004 17.4 4.4 0.094 13.0 0.0 3.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD24072.1 - 0.012 16.4 2.6 8 7.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD24072.1 - 0.012 15.8 0.0 15 6.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD24072.1 - 0.056 13.1 0.0 4 7.2 0.0 3.3 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 PVD24072.1 - 0.49 11.1 2.9 33 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PHR PF08005.12 PVD24074.1 - 7.1e-19 69.0 0.0 1.3e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 PVD24074.1 - 1.2e-17 64.1 0.0 3.8e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD24074.1 - 1e-05 25.6 0.8 4e-05 23.6 0.8 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch Pkinase_Tyr PF07714.17 PVD24076.1 - 1.3e-83 280.3 0.0 2.1e-82 276.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD24076.1 - 5.5e-37 127.6 0.0 9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ephrin_rec_like PF07699.13 PVD24076.1 - 1.6e-16 59.8 31.9 5.6e-09 35.6 4.1 3.8 3 0 0 3 3 3 2 Putative ephrin-receptor like Adeno_E3_CR2 PF02439.15 PVD24076.1 - 0.00044 19.9 3.6 0.00079 19.1 3.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 YqgF PF14639.6 PVD24076.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 SKG6 PF08693.10 PVD24076.1 - 0.17 11.3 2.5 0.35 10.3 2.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Bax1-I PF01027.20 PVD24078.1 - 1.8e-47 161.9 27.5 2e-47 161.7 27.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 OTU PF02338.19 PVD24079.1 - 4.3e-08 33.7 0.0 8.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 PVD24079.1 - 0.062 13.6 0.4 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Peptidase_C12 PF01088.21 PVD24080.1 - 1.2e-64 218.0 0.4 1.3e-63 214.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PVD24080.1 - 1.7e-15 56.6 0.2 5.3e-15 55.0 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases ALGX PF16822.5 PVD24080.1 - 0.065 12.9 2.1 0.082 12.6 0.1 2.1 3 0 0 3 3 3 0 SGNH hydrolase-like domain, acetyltransferase AlgX Macoilin PF09726.9 PVD24080.1 - 0.87 8.1 15.7 1.2 7.6 15.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF1840 PF08895.11 PVD24080.1 - 8.8 6.7 7.9 1.4 9.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) DmpG_comm PF07836.11 PVD24082.1 - 0.0013 18.2 0.3 1e+02 2.6 0.0 6.4 3 2 6 10 10 10 0 DmpG-like communication domain Fcf2 PF08698.11 PVD24082.1 - 0.24 11.8 0.8 34 4.9 0.2 3.5 1 1 1 2 2 2 0 Fcf2 pre-rRNA processing Pkinase PF00069.25 PVD24083.1 - 1.4e-10 41.0 0.0 3e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain TBK1_ULD PF18396.1 PVD24083.1 - 4.9e-07 29.6 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 PVD24083.1 - 0.022 14.0 0.0 0.2 10.9 0.0 2.1 1 1 1 2 2 2 0 Protein tyrosine kinase DUF1664 PF07889.12 PVD24083.1 - 0.073 13.1 1.4 3.1 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Trimer_CC PF08954.11 PVD24083.1 - 0.098 12.2 0.2 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 Trimerisation motif Syntaxin-6_N PF09177.11 PVD24083.1 - 0.1 13.2 1.5 0.49 11.0 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ADP_ribosyl_GH PF03747.14 PVD24084.1 - 7.1e-40 137.5 0.4 2.5e-20 73.4 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase DMP12 PF16779.5 PVD24084.1 - 0.044 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 DNA-mimic protein ADP_ribosyl_GH PF03747.14 PVD24085.1 - 9.7e-43 147.0 0.0 1.3e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_8 PF13855.6 PVD24085.1 - 1.1e-20 73.1 26.3 1.4e-09 37.6 2.5 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PVD24085.1 - 2.9e-13 49.8 9.5 3.1e-05 24.2 1.0 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD24085.1 - 0.0019 17.7 0.9 0.0051 16.3 0.9 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PVD24085.1 - 0.0057 16.6 9.7 0.16 12.1 0.2 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 PVD24085.1 - 0.015 15.7 17.1 1.8 9.4 0.3 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4675 PF15720.5 PVD24085.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) IMUP PF15761.5 PVD24085.1 - 4 8.2 4.9 7.5 7.3 4.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TraB PF01963.17 PVD24086.1 - 3.7e-32 112.3 0.0 5.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 TraB family Na_trans_assoc PF06512.13 PVD24086.1 - 0.092 13.0 5.6 0.14 12.4 5.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 PVD24086.1 - 0.11 11.9 4.8 0.15 11.5 4.8 1.2 1 0 0 1 1 1 0 SDA1 ACT_7 PF13840.6 PVD24086.1 - 0.13 12.1 0.2 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain Pox_Ag35 PF03286.14 PVD24086.1 - 0.16 11.8 3.3 0.25 11.1 3.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 PVD24086.1 - 0.2 9.9 1.2 0.24 9.7 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 PVD24086.1 - 1.2 8.7 9.9 17 4.9 8.2 2.2 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 PVD24086.1 - 1.2 7.2 7.5 1.6 6.9 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PVD24086.1 - 2.1 6.3 11.4 3 5.9 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4550 PF15084.6 PVD24087.1 - 6.9e-38 129.0 0.9 1.6e-37 127.8 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) RCDG1 PF15725.5 PVD24087.1 - 6.7 7.2 7.2 0.57 10.6 1.3 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein LicD PF04991.13 PVD24088.1 - 4.7e-22 79.2 0.2 2e-16 60.8 0.2 2.3 1 1 1 2 2 2 2 LicD family p450 PF00067.22 PVD24090.1 - 2.2e-10 39.9 0.0 2.7e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD24091.1 - 5.8e-59 200.1 0.0 6.8e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CLP1_P PF16575.5 PVD24093.1 - 8e-37 126.9 0.0 1.7e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 PVD24093.1 - 0.075 13.1 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 PVD24093.1 - 0.14 12.0 1.6 0.19 11.6 0.0 2.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea BORCS6 PF10157.9 PVD24094.1 - 2.7e-26 92.6 6.6 1.5e-17 64.2 0.4 2.8 2 1 1 3 3 3 2 BLOC-1-related complex sub-unit 6 Brix PF04427.18 PVD24095.1 - 1.6e-31 109.9 0.3 2.5e-31 109.3 0.3 1.3 1 0 0 1 1 1 1 Brix domain Isy1 PF06246.12 PVD24096.1 - 1.1e-95 320.0 8.7 1.3e-95 319.8 8.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family HHA PF05321.11 PVD24097.1 - 0.027 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 Haemolysin expression modulating protein Dicty_REP PF05086.12 PVD24097.1 - 1.6 6.6 4.4 2.3 6.1 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RhoGEF PF00621.20 PVD24098.1 - 3.6e-34 118.6 4.1 7.7e-34 117.5 4.1 1.6 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 PVD24098.1 - 5.7e-20 71.2 5.9 5.7e-20 71.2 5.9 2.7 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 PVD24098.1 - 1.6e-08 35.0 0.0 6.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 PVD24098.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_13 PF16652.5 PVD24098.1 - 0.081 12.7 1.2 8.6 6.2 1.2 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase_C PF00433.24 PVD24099.1 - 0.073 13.8 0.1 0.12 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain LRR_8 PF13855.6 PVD24101.1 - 1.8e-45 152.5 30.2 1e-15 57.2 5.9 6.1 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD24101.1 - 6e-27 93.3 29.3 3.2e-06 27.4 0.0 6.7 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24101.1 - 4e-14 52.7 0.2 9.4e-10 38.5 0.0 2.8 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD24101.1 - 4.4e-13 47.8 27.0 1.7 9.5 0.2 10.3 9 2 0 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.6 PVD24101.1 - 4.8e-08 32.4 32.4 1.1 9.5 0.1 9.3 10 0 0 10 10 10 6 Leucine Rich repeat LRR_9 PF14580.6 PVD24101.1 - 1.6e-05 24.5 9.1 0.31 10.5 0.1 3.5 1 1 1 3 3 3 3 Leucine-rich repeat CD225 PF04505.12 PVD24102.1 - 2.9e-07 30.5 0.2 5.3e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 PVD24102.1 - 0.049 13.4 0.5 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF4079 PF13301.6 PVD24102.1 - 0.053 13.7 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Amastin PF07344.11 PVD24102.1 - 0.056 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF2269 PF10027.9 PVD24102.1 - 0.08 13.0 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF4328 PF14219.6 PVD24102.1 - 0.56 9.7 3.8 1.7 8.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) DDE_5 PF13546.6 PVD24103.1 - 0.0014 18.0 1.0 0.0017 17.7 1.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.21 PVD24105.1 - 8.8e-42 143.2 21.2 1.2e-41 142.8 21.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD24105.1 - 7e-09 35.7 12.6 7e-09 35.7 12.6 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD24105.1 - 3.4e-08 33.2 21.4 4.8e-08 32.7 21.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_L29e PF01779.17 PVD24106.1 - 7.2e-16 58.2 1.1 7.2e-16 58.2 1.1 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family PadR PF03551.14 PVD24107.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family UvrB PF12344.8 PVD24107.1 - 0.32 10.9 1.5 4.3 7.3 0.6 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B Lectin_C PF00059.21 PVD24108.1 - 3.7e-14 53.4 1.3 1.3e-13 51.6 0.0 2.2 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 PVD24108.1 - 0.041 13.8 5.6 0.089 12.8 5.0 2.0 1 1 0 1 1 1 0 PAN domain PAN_4 PF14295.6 PVD24108.1 - 0.097 12.6 2.3 0.27 11.2 2.3 1.7 1 0 0 1 1 1 0 PAN domain EGF_MSP1_1 PF12946.7 PVD24108.1 - 5.5 7.1 7.3 16 5.7 0.2 2.8 3 0 0 3 3 3 0 MSP1 EGF domain 1 Lectin_C PF00059.21 PVD24109.1 - 5.6e-05 23.8 0.0 0.00017 22.3 0.0 1.8 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 PVD24109.1 - 0.096 12.7 5.8 0.29 11.1 2.2 2.4 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.6 PVD24109.1 - 2.1 8.3 6.3 3.3 7.7 3.3 2.7 2 1 0 2 2 2 0 PAN domain Lectin_C PF00059.21 PVD24110.1 - 8.6e-11 42.5 0.1 1.3e-10 42.0 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 PVD24110.1 - 0.1 11.9 0.4 0.43 9.8 0.1 2.0 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 PVD24111.1 - 2.6e-05 24.9 0.0 5.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD24112.1 - 4e-12 46.8 0.6 9.5e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 Lectin C-type domain Lectin_C PF00059.21 PVD24113.1 - 5.1e-07 30.4 0.1 1.4e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 Lectin C-type domain zf-UBP PF02148.19 PVD24115.1 - 1.9e-18 66.5 7.7 3.2e-18 65.8 7.7 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 PVD24115.1 - 0.00061 19.5 0.2 0.0012 18.5 0.2 1.5 1 0 0 1 1 1 1 Variant UBP zinc finger zinc_ribbon_9 PF14369.6 PVD24115.1 - 0.094 13.0 0.0 0.094 13.0 0.0 4.0 5 0 0 5 5 5 0 zinc-ribbon DUF4428 PF14471.6 PVD24115.1 - 0.35 10.8 5.4 8.2 6.4 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Ashwin PF15323.6 PVD24115.1 - 0.39 10.7 5.1 0.68 9.9 5.1 1.3 1 0 0 1 1 1 0 Developmental protein HypA PF01155.19 PVD24115.1 - 0.59 10.2 5.9 7.3 6.7 0.1 3.2 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-B_box PF00643.24 PVD24115.1 - 4 7.7 12.6 1.9 8.7 3.5 3.2 3 0 0 3 3 3 0 B-box zinc finger ArfGap PF01412.18 PVD24115.1 - 4.5 7.4 10.7 0.3 11.2 1.2 2.9 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf PIR PF00399.19 PVD24116.1 - 0.0031 17.0 1.7 0.0056 16.2 1.7 1.4 1 0 0 1 1 1 1 Yeast PIR protein repeat Hist_deacetyl PF00850.19 PVD24119.1 - 6.1e-148 492.3 0.1 6.4e-77 259.0 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain DUF2946 PF11162.8 PVD24119.1 - 0.23 12.1 2.5 0.28 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) PNMA PF14893.6 PVD24120.1 - 0.0002 20.9 0.1 0.00037 20.0 0.1 1.4 1 0 0 1 1 1 1 PNMA dUTPase PF00692.19 PVD24120.1 - 0.094 12.4 0.6 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 dUTPase Gelsolin PF00626.22 PVD24121.1 - 4e-41 138.8 0.1 4.6e-16 58.5 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat VWA_N PF08399.11 PVD24122.1 - 3.8e-31 108.1 3.0 4.6e-31 107.9 1.1 2.2 2 0 0 2 2 2 1 VWA N-terminal VWA_3 PF13768.6 PVD24122.1 - 1.9e-14 53.9 0.0 5.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD24122.1 - 1.3e-13 51.6 1.1 8e-13 49.0 0.5 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24122.1 - 6e-13 49.4 0.8 5.8e-12 46.2 0.6 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain dCache_1 PF02743.18 PVD24122.1 - 1.5e-06 28.2 0.2 0.048 13.4 0.0 3.7 3 1 0 3 3 3 2 Cache domain CobT_C PF11775.8 PVD24122.1 - 0.15 11.7 0.3 0.43 10.2 0.3 1.8 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain DUF3915 PF13054.6 PVD24123.1 - 1.7 8.7 4.1 2.6 8.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) EphA2_TM PF14575.6 PVD24126.1 - 0.012 16.4 0.0 0.096 13.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DR2241 PF18069.1 PVD24126.1 - 0.046 13.6 0.2 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 DR2241 stabilising domain DnaJ-X PF14308.6 PVD24126.1 - 0.06 12.8 1.2 2.7 7.4 0.2 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing DUF4381 PF14316.6 PVD24126.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.15 PVD24126.1 - 0.13 12.2 0.4 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.6 PVD24128.1 - 0.008 17.0 0.0 0.028 15.3 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF3948 PF13134.6 PVD24128.1 - 0.12 12.1 0.5 0.19 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Adeno_E3_CR2 PF02439.15 PVD24128.1 - 0.44 10.4 12.0 0.18 11.6 6.4 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SCAN PF02023.17 PVD24129.1 - 1.6e-13 50.3 0.2 2.8e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 SCAN domain Neurexophilin PF06312.12 PVD24129.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 PVD24129.1 - 0.18 12.6 0.0 0.5 11.2 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat vATP-synt_E PF01991.18 PVD24129.1 - 0.23 10.8 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit baeRF_family10 PF18854.1 PVD24129.1 - 1.1 9.5 5.9 0.53 10.5 0.1 2.9 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 10 ABC_tran PF00005.27 PVD24131.1 - 6.1e-50 169.3 0.0 2.8e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PVD24131.1 - 1e-40 139.9 36.3 9.8e-17 61.1 22.1 3.3 2 1 1 3 3 3 3 ABC-2 family transporter protein AAA_21 PF13304.6 PVD24131.1 - 1.2e-22 81.1 0.2 3e-08 33.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PVD24131.1 - 3.1e-05 24.6 2.5 0.037 14.5 0.3 2.3 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 PVD24131.1 - 0.00015 22.4 0.0 0.19 12.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SbcCD_C PF13558.6 PVD24131.1 - 0.0002 21.5 0.0 0.87 9.9 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 PVD24131.1 - 0.00046 19.7 0.0 5.2 6.4 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PVD24131.1 - 0.0032 17.4 0.5 0.27 11.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 PVD24131.1 - 0.0075 16.0 0.1 5.8 6.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PVD24131.1 - 0.0091 15.7 0.1 0.6 9.7 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 PVD24131.1 - 0.012 15.4 2.1 0.81 9.5 0.5 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PVD24131.1 - 0.018 14.3 0.1 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 PVD24131.1 - 0.052 13.8 2.0 2.7 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 PVD24131.1 - 0.095 12.5 3.3 0.3 10.9 0.2 2.5 3 0 0 3 3 3 0 MukB N-terminal SRP54 PF00448.22 PVD24131.1 - 0.1 12.2 4.3 1.2 8.8 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 PVD24131.1 - 0.12 12.0 2.4 1.5 8.5 0.2 2.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 PVD24131.1 - 0.16 12.0 0.2 18 5.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Kelch_1 PF01344.25 PVD24132.1 - 3.3e-42 141.8 2.7 6.1e-12 44.9 0.0 7.4 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 PVD24132.1 - 7.2e-36 121.3 0.1 2.6e-07 30.7 0.0 6.7 3 2 3 6 6 6 5 Kelch motif BACK PF07707.15 PVD24132.1 - 6.9e-28 96.8 0.3 6.9e-28 96.8 0.3 2.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 PVD24132.1 - 1.9e-26 92.5 0.0 3.4e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PVD24132.1 - 2.2e-25 88.4 0.0 0.0016 18.7 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD24132.1 - 2.1e-20 72.4 0.1 4.1e-05 23.5 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD24132.1 - 2.4e-20 71.7 0.0 0.003 17.5 0.0 7.2 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.6 PVD24132.1 - 1.3e-15 57.0 0.0 0.00013 21.9 0.0 5.8 6 0 0 6 6 6 3 Kelch motif ANF_receptor PF01094.28 PVD24132.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region Methyltransf_31 PF13847.6 PVD24133.1 - 8.3e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD24133.1 - 8.6e-14 52.0 0.0 2.2e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD24133.1 - 1.5e-13 51.3 0.0 1e-12 48.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD24133.1 - 3.3e-13 50.1 0.0 1.3e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD24133.1 - 1.9e-12 47.3 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD24133.1 - 5e-06 26.0 0.0 1.4e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 PVD24133.1 - 2.1e-05 24.2 0.0 9.6e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Nodulation protein S (NodS) Rrf2 PF02082.20 PVD24133.1 - 8.6e-05 22.8 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator CMAS PF02353.20 PVD24133.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 PVD24133.1 - 0.00016 22.6 0.0 0.0085 17.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD24133.1 - 0.00031 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 PVD24133.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 PVD24133.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 PVD24133.1 - 0.0044 16.6 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 PVD24133.1 - 0.038 13.6 0.0 0.085 12.4 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TRM13 PF05206.14 PVD24133.1 - 0.061 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_18 PF12847.7 PVD24133.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrmB PF01978.19 PVD24133.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_9 PF08003.11 PVD24133.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cu-oxidase_3 PF07732.15 PVD24134.1 - 2.1e-41 140.7 0.4 1.2e-40 138.2 0.3 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD24134.1 - 2.1e-35 121.5 10.3 4.9e-30 104.1 0.1 4.6 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 PVD24134.1 - 3.5e-26 92.2 0.4 4.2e-23 82.2 0.3 4.0 4 2 0 4 4 4 1 Multicopper oxidase Shisa PF13908.6 PVD24135.1 - 1.3e-05 25.5 1.1 1.7e-05 25.2 1.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PNTB PF02233.16 PVD24135.1 - 0.02 13.8 0.4 0.023 13.6 0.4 1.0 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit CYYR1 PF10873.8 PVD24135.1 - 0.055 13.9 19.5 0.19 12.1 19.5 1.8 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 PVD24135.1 - 0.61 11.0 2.0 1.2 10.1 2.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 PVD24136.1 - 0.0044 16.4 0.4 0.011 15.1 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMIE PF16038.5 PVD24136.1 - 0.01 15.7 0.7 0.02 14.7 0.7 1.4 1 0 0 1 1 1 0 TMIE protein Rhabdo_glycop PF00974.18 PVD24136.1 - 0.075 11.5 0.3 0.12 10.8 0.3 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PDR_assoc PF08370.11 PVD24136.1 - 0.19 11.5 0.3 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated WBP-1 PF11669.8 PVD24136.1 - 1.1 9.9 8.9 0.14 12.8 3.0 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 WBP-1 PF11669.8 PVD24138.1 - 0.0072 16.9 9.0 0.015 15.9 9.0 1.6 1 1 0 1 1 1 1 WW domain-binding protein 1 RCR PF12273.8 PVD24138.1 - 0.011 16.4 0.1 0.017 15.8 0.1 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red NCU-G1 PF15065.6 PVD24138.1 - 0.077 12.0 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 SCIMP PF15050.6 PVD24138.1 - 0.1 13.1 3.0 0.27 11.7 3.0 1.7 1 0 0 1 1 1 0 SCIMP protein EphA2_TM PF14575.6 PVD24138.1 - 0.11 13.4 1.7 0.15 12.9 1.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 PVD24138.1 - 0.33 11.0 3.2 9.6 6.3 1.6 2.3 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Collectrin PF16959.5 PVD24138.1 - 0.34 10.7 3.7 0.58 9.9 3.7 1.3 1 0 0 1 1 1 0 Renal amino acid transporter CD34_antigen PF06365.12 PVD24138.1 - 0.36 10.4 1.9 0.49 9.9 1.9 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 PVD24138.1 - 0.38 10.8 5.0 0.39 10.8 1.6 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment LRR19-TM PF15176.6 PVD24138.1 - 1.4 9.0 4.5 2.2 8.3 4.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Adeno_E3_CR2 PF02439.15 PVD24138.1 - 2.8 7.8 15.2 0.057 13.2 7.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 PVD24138.1 - 3 8.0 18.6 4.1 7.6 18.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Shisa PF13908.6 PVD24139.1 - 0.01 16.1 18.7 0.023 14.9 18.7 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 PVD24139.1 - 0.042 14.7 0.2 0.091 13.7 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 PVD24139.1 - 0.07 12.5 0.2 0.07 12.5 0.2 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Insulin_TMD PF17870.1 PVD24139.1 - 0.1 12.7 0.5 0.17 11.9 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMIE PF16038.5 PVD24139.1 - 0.13 12.2 6.7 0.26 11.2 6.7 1.5 1 0 0 1 1 1 0 TMIE protein RCR PF12273.8 PVD24139.1 - 0.13 12.9 6.4 0.97 10.1 6.4 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Collectrin PF16959.5 PVD24139.1 - 0.29 10.9 1.0 0.44 10.3 1.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter CD34_antigen PF06365.12 PVD24139.1 - 0.3 10.6 0.7 0.4 10.2 0.7 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.6 PVD24140.1 - 0.0054 17.0 1.3 0.0054 17.0 1.3 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 PVD24140.1 - 0.022 14.7 1.0 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF2970 PF11174.8 PVD24140.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF1275 PF06912.11 PVD24140.1 - 0.041 13.8 1.1 0.067 13.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Shisa PF13908.6 PVD24141.1 - 9.2e-05 22.8 0.1 9.2e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator ATP1G1_PLM_MAT8 PF02038.16 PVD24142.1 - 0.049 13.1 1.6 0.093 12.2 1.6 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Podoplanin PF05808.11 PVD24142.1 - 0.058 13.5 1.1 0.096 12.8 1.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF3185 PF11381.8 PVD24142.1 - 0.26 11.3 6.4 5.2 7.2 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) TMIE PF16038.5 PVD24143.1 - 0.00069 19.4 5.9 0.019 14.8 0.7 2.6 2 0 0 2 2 2 2 TMIE protein SKG6 PF08693.10 PVD24143.1 - 0.011 15.2 0.4 0.011 15.2 0.4 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4489 PF14879.6 PVD24143.1 - 0.046 13.8 11.0 0.14 12.2 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4489) DUF2976 PF11190.8 PVD24143.1 - 0.14 12.0 0.7 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) EphA2_TM PF14575.6 PVD24143.1 - 0.17 12.8 6.1 4.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 PVD24143.1 - 1.3 9.8 4.6 1.5 9.6 0.1 2.8 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 PVD24143.1 - 2.1 8.2 16.4 3.4 7.5 1.7 3.3 2 1 0 2 2 2 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 PVD24143.1 - 2.6 8.4 4.2 1 9.6 0.4 2.2 2 1 0 2 2 2 0 Protein melan-A Podoplanin PF05808.11 PVD24143.1 - 4.9 7.2 10.7 0.6 10.2 0.9 2.6 2 1 0 2 2 2 0 Podoplanin DUF3290 PF11694.8 PVD24144.1 - 0.037 14.0 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) EphA2_TM PF14575.6 PVD24144.1 - 0.046 14.6 0.3 0.26 12.2 0.0 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3382 PF11862.8 PVD24144.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Podoplanin PF05808.11 PVD24144.1 - 0.11 12.6 0.2 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Podoplanin FixQ PF05545.11 PVD24144.1 - 0.14 12.2 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SecE PF00584.20 PVD24144.1 - 1.1 9.2 5.0 1.1 9.2 2.6 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Shisa PF13908.6 PVD24146.1 - 1.7e-05 25.1 15.4 2.5e-05 24.6 15.4 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 PVD24146.1 - 0.068 13.4 1.2 0.15 12.3 0.2 1.8 1 1 1 2 2 2 0 Glycophorin A EphA2_TM PF14575.6 PVD24146.1 - 0.069 14.0 0.9 0.1 13.5 0.2 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD24146.1 - 0.098 12.7 0.4 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Collectrin PF16959.5 PVD24146.1 - 0.14 11.9 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Renal amino acid transporter TMIE PF16038.5 PVD24146.1 - 0.17 11.8 6.9 0.39 10.6 6.9 1.6 1 0 0 1 1 1 0 TMIE protein CD20 PF04103.15 PVD24146.1 - 0.22 11.6 11.2 0.53 10.4 11.2 1.6 1 1 0 1 1 1 0 CD20-like family DAG1 PF05454.11 PVD24146.1 - 0.51 9.7 2.1 0.35 10.2 0.4 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PIRT PF15099.6 PVD24146.1 - 0.55 9.8 2.0 0.82 9.3 2.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family RCR PF12273.8 PVD24146.1 - 2.2 8.9 11.0 0.95 10.1 6.3 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pentapeptide PF00805.22 PVD24148.1 - 1.8e-11 43.4 0.0 0.0043 16.7 0.0 3.4 1 1 2 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 PVD24148.1 - 0.00044 20.3 0.0 0.62 10.3 0.0 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) SICA_C PF12879.7 PVD24148.1 - 0.047 13.7 0.3 6.6 6.7 0.3 2.8 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain Pentapeptide_4 PF13599.6 PVD24148.1 - 0.11 12.7 0.0 4 7.7 0.0 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) SAM_PNT PF02198.16 PVD24148.1 - 1.3 9.0 6.5 2.7e+02 1.6 0.1 3.9 1 1 1 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Podoplanin PF05808.11 PVD24150.1 - 0.03 14.4 3.8 0.051 13.7 3.8 1.3 1 0 0 1 1 1 0 Podoplanin TMEM52 PF14979.6 PVD24150.1 - 0.072 13.0 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 WBP-1 PF11669.8 PVD24150.1 - 2.4 8.8 15.2 50 4.6 15.2 2.3 1 1 0 1 1 1 0 WW domain-binding protein 1 CYYR1 PF10873.8 PVD24151.1 - 0.0042 17.5 31.3 0.0042 17.5 31.3 2.3 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 K1377 PF15352.6 PVD24151.1 - 0.33 9.2 0.2 0.39 8.9 0.2 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy WBP-1 PF11669.8 PVD24151.1 - 1.1 9.9 9.8 8.5 7.1 9.8 2.4 1 1 0 1 1 1 0 WW domain-binding protein 1 CECR6_TMEM121 PF14997.6 PVD24152.1 - 1e-28 100.5 2.2 1.4e-28 100.0 2.2 1.1 1 0 0 1 1 1 1 CECR6/TMEM121 family MFS_1 PF07690.16 PVD24155.1 - 0.0025 16.8 17.0 0.0058 15.6 17.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2104 PF09877.9 PVD24155.1 - 0.1 12.8 6.9 0.052 13.8 4.1 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) EF-hand_1 PF00036.32 PVD24156.1 - 4.6e-12 44.6 0.4 2.8e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 PVD24156.1 - 1.5e-11 43.2 0.7 6.7e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD24156.1 - 1.2e-10 40.5 0.2 0.00081 19.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PVD24156.1 - 1.7e-09 38.0 0.8 1.1e-06 29.0 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD24156.1 - 0.012 15.5 0.7 0.075 12.9 0.3 2.1 1 1 1 2 2 2 0 EF-hand domain pair Dockerin_1 PF00404.18 PVD24156.1 - 0.014 15.6 1.9 0.48 10.7 0.2 2.5 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 PVD24156.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Caleosin related protein VCBS PF13517.6 PVD24156.1 - 0.073 13.7 3.3 0.48 11.1 3.3 2.4 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PVD24156.1 - 2.6 8.3 8.4 0.66 10.2 1.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat RtcB PF01139.17 PVD24157.1 - 1.3e-34 120.1 0.0 6.8e-30 104.6 0.0 2.1 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB Dehydratase_MU PF02288.15 PVD24157.1 - 0.1 12.5 0.1 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Dehydratase medium subunit Spore_III_AB PF09548.10 PVD24157.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ThiF PF00899.21 PVD24158.1 - 9.3e-59 198.7 0.0 1.3e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 PVD24158.1 - 3.5e-23 81.5 0.2 5.5e-23 80.9 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain Pyr_redox PF00070.27 PVD24158.1 - 0.0037 17.8 0.2 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UAE_UbL PF14732.6 PVD24158.1 - 0.0092 16.6 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 PVD24158.1 - 0.025 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 PVD24158.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F-box-like PF12937.7 PVD24159.1 - 1.2e-07 31.5 1.5 1.2e-07 31.5 1.5 2.6 3 0 0 3 3 3 1 F-box-like PI31_Prot_N PF11566.8 PVD24159.1 - 1.9e-05 24.5 0.0 4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box PF00646.33 PVD24159.1 - 0.00017 21.4 1.3 0.00017 21.4 1.3 2.1 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.11 PVD24159.1 - 0.14 12.7 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ins_P5_2-kin PF06090.12 PVD24160.1 - 2.6e-75 253.9 0.1 3.1e-75 253.7 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nfu_N PF08712.11 PVD24160.1 - 0.092 12.8 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal CwsA PF10814.8 PVD24161.1 - 0.017 15.3 0.0 0.095 12.9 0.0 1.9 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF3040 PF11239.8 PVD24161.1 - 0.031 14.5 2.0 5.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SLAC1 PF03595.17 PVD24161.1 - 0.037 13.3 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel Neurensin PF14927.6 PVD24161.1 - 0.054 13.2 0.5 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 Neurensin DUF2371 PF10177.9 PVD24161.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Guanylate_cyc PF00211.20 PVD24162.1 - 4.9e-29 101.3 0.2 8.3e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD24162.1 - 1e-26 93.7 0.3 3.3e-16 59.4 0.1 2.2 2 0 0 2 2 2 2 Heme NO binding associated HNOB PF07700.15 PVD24162.1 - 7.9e-22 78.0 0.0 1.6e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Haem-NO-binding zf-C3HC4_3 PF13920.6 PVD24163.1 - 1.3e-08 34.5 11.2 3.3e-08 33.3 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD24163.1 - 3.1e-08 33.3 14.5 3.1e-08 33.3 14.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD24163.1 - 1.3e-07 31.8 15.5 2.5e-07 30.9 14.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PVD24163.1 - 1.6e-05 24.6 14.6 1.6e-05 24.6 14.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD24163.1 - 5.7e-05 22.9 11.6 5.7e-05 22.9 11.6 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PVD24163.1 - 0.00013 22.1 10.3 0.00068 19.9 10.3 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-CCHH PF10283.9 PVD24163.1 - 0.00054 19.9 4.2 0.00054 19.9 4.2 2.3 2 0 0 2 2 2 1 PBZ domain zf-RING_UBOX PF13445.6 PVD24163.1 - 0.001 19.1 10.1 0.0031 17.5 10.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 PVD24163.1 - 0.0014 18.7 8.3 0.0014 18.7 8.3 2.1 3 0 0 3 3 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 PVD24163.1 - 0.003 17.4 4.9 0.0078 16.1 4.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 PVD24163.1 - 0.0048 16.8 12.6 0.0048 16.8 12.6 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD24163.1 - 0.11 12.7 15.1 0.29 11.3 15.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MLD PF11647.8 PVD24163.1 - 0.13 12.6 0.2 0.44 10.8 0.1 1.9 2 0 0 2 2 2 0 Membrane Localization Domain zf-RING_4 PF14570.6 PVD24163.1 - 0.21 11.4 10.2 0.64 9.9 10.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 PVD24163.1 - 0.25 11.5 3.0 0.7 10.0 3.0 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 PVD24163.1 - 8.7 6.5 9.2 2.1 8.5 5.5 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sushi PF00084.20 PVD24166.1 - 4.6e-07 30.3 1.2 7.4e-07 29.7 1.2 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Sacchrp_dh_C PF16653.5 PVD24167.1 - 3.3e-58 197.9 0.0 1.5e-57 195.7 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Cytochrom_B561 PF03188.16 PVD24167.1 - 5.4e-26 91.4 14.8 1.2e-25 90.2 14.8 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 AlaDh_PNT_N PF05222.15 PVD24167.1 - 7.1e-26 91.1 0.1 1.5e-25 90.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 PVD24167.1 - 1.8e-21 76.7 0.0 5.3e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 PVD24167.1 - 1.6e-07 30.8 0.0 6e-06 25.7 0.0 3.1 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 PVD24167.1 - 0.0043 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 PVD24167.1 - 0.037 14.1 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus IPTL-CTERM PF18203.1 PVD24167.1 - 0.04 13.8 0.8 0.17 11.8 0.8 2.1 1 0 0 1 1 1 0 IPTL-CTERM motif NAD_binding_3 PF03447.16 PVD24167.1 - 0.048 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Tubulin PF00091.25 PVD24169.1 - 4e-52 177.3 0.0 4.9e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD24169.1 - 0.00027 20.7 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4371 PF14291.6 PVD24170.1 - 2.9e-05 23.8 0.4 0.00081 19.1 0.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) Kelch_1 PF01344.25 PVD24172.1 - 2.1e-50 168.1 0.1 7.6e-09 35.0 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 PVD24172.1 - 4e-39 131.6 0.1 1e-07 32.0 0.0 6.7 3 2 4 7 7 7 6 Kelch motif Kelch_4 PF13418.6 PVD24172.1 - 7.6e-37 125.1 0.0 3.4e-07 30.1 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD24172.1 - 3.4e-26 91.0 0.0 6.8e-06 26.2 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD24172.1 - 3.4e-22 77.5 0.1 5.4e-05 23.0 0.0 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.6 PVD24172.1 - 2.7e-16 59.1 0.2 0.0038 17.2 0.0 6.3 7 0 0 7 7 7 4 Kelch motif DUF1668 PF07893.13 PVD24172.1 - 0.043 13.2 0.0 0.14 11.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) Hormone_recep PF00104.30 PVD24173.1 - 9.9e-35 120.0 0.2 1.9e-34 119.1 0.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD24173.1 - 5.3e-31 106.9 12.4 9.4e-31 106.1 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SUKH-4 PF14435.6 PVD24173.1 - 0.043 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 SUKH-4 immunity protein DUF563 PF04577.14 PVD24174.1 - 5.6e-23 82.2 0.1 9.7e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TMEM208_SND2 PF05620.11 PVD24175.1 - 4.5 7.0 6.2 3.9 7.2 2.0 2.2 1 1 2 3 3 3 0 SRP-independent targeting protein 2/TMEM208 TSP_3 PF02412.18 PVD24176.1 - 0.21 11.3 47.6 0.23 11.2 7.8 6.2 1 1 4 5 5 5 0 Thrombospondin type 3 repeat HSP90 PF00183.18 PVD24179.1 - 2.1e-227 756.1 27.8 3.5e-227 755.4 27.8 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PVD24179.1 - 3.6e-13 50.0 0.1 7.1e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PVD24179.1 - 1.2e-09 38.1 0.1 3.4e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_16 PF13191.6 PVD24180.1 - 1e-07 32.5 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PVD24180.1 - 4e-07 30.1 0.0 7.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF4062 PF13271.6 PVD24180.1 - 6.6e-06 26.4 0.0 3.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) AAA_22 PF13401.6 PVD24180.1 - 0.00095 19.4 0.0 0.0037 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 PVD24180.1 - 0.0027 17.6 0.1 0.79 9.6 0.0 2.3 2 0 0 2 2 2 2 Helicase DUF2188 PF09954.9 PVD24180.1 - 0.072 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DAP3 PF10236.9 PVD24180.1 - 0.078 12.1 0.0 0.39 9.8 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 PVD24180.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PVD24180.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PVD24180.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 PVD24180.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 PVD24180.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ldl_recept_a PF00057.18 PVD24181.1 - 1.2 9.4 4.5 0.27 11.5 0.9 1.9 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD24182.1 - 0.00014 22.0 1.1 0.00014 22.0 1.1 4.1 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD24183.1 - 1.1e-15 57.5 33.1 1.5e-05 25.1 1.6 5.2 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A LRR_4 PF12799.7 PVD24183.1 - 8.1e-06 26.1 13.9 0.00042 20.6 3.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD24183.1 - 8.2e-06 25.5 5.4 8.2e-06 25.5 5.4 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 PVD24183.1 - 0.081 13.5 6.1 0.11 13.1 0.7 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat WD40 PF00400.32 PVD24184.1 - 3e-36 122.8 11.4 4.6e-06 27.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD24184.1 - 3.8e-05 23.9 0.1 0.51 10.7 0.0 4.6 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain An_peroxidase PF03098.15 PVD24185.1 - 5.9e-137 457.4 0.0 1.7e-116 389.9 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase Kelch_1 PF01344.25 PVD24186.1 - 1.7e-36 123.5 6.3 2.7e-14 52.4 0.1 6.2 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD24186.1 - 3.3e-22 78.0 8.0 4.8e-06 26.7 0.0 6.7 2 2 4 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD24186.1 - 7.3e-21 73.3 2.5 1.6e-05 24.7 0.0 5.8 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 PVD24186.1 - 1.6e-20 73.4 0.1 3.1e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 PVD24186.1 - 3.5e-17 62.1 1.4 4.7e-05 23.3 0.0 6.3 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD24186.1 - 2e-16 59.8 3.9 0.0026 18.0 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.15 PVD24186.1 - 9.2e-15 54.6 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 PVD24186.1 - 3.2e-12 46.1 1.1 0.025 14.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Pkinase PF00069.25 PVD24187.1 - 6.1e-24 84.8 0.0 2.2e-21 76.4 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24187.1 - 2.3e-17 63.1 0.0 4e-12 46.0 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD24187.1 - 0.014 14.2 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase PAP_central PF04928.17 PVD24187.1 - 0.014 14.4 0.0 0.1 11.5 0.0 2.3 1 1 0 1 1 1 0 Poly(A) polymerase central domain Metallophos_2 PF12850.7 PVD24187.1 - 0.019 15.2 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DUF465 PF04325.13 PVD24187.1 - 0.019 15.0 1.7 0.052 13.6 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) PALP PF00291.25 PVD24188.1 - 2.7e-55 187.8 0.0 3.4e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme XFP_C PF09363.10 PVD24188.1 - 0.18 11.2 0.1 0.31 10.5 0.1 1.3 1 0 0 1 1 1 0 XFP C-terminal domain DUF1397 PF07165.11 PVD24190.1 - 0.011 15.1 10.5 0.023 14.1 10.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) DUF19 PF01579.18 PVD24190.1 - 0.018 14.9 7.6 0.038 13.8 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF19) MINDY_DUB PF04424.13 PVD24190.1 - 0.15 12.1 0.2 0.55 10.3 0.2 1.9 2 1 0 2 2 2 0 MINDY deubiquitinase ADH_zinc_N PF00107.26 PVD24191.1 - 9.5e-24 83.8 0.1 1.5e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24191.1 - 2e-16 59.9 0.0 6.4e-11 42.1 0.0 2.5 1 1 1 2 2 2 2 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 PVD24191.1 - 2.6e-07 31.8 0.0 4.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD24192.1 - 7.3e-05 23.8 0.0 7.7e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24193.1 - 3.3e-28 97.7 0.0 1e-27 96.2 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PVD24193.1 - 2.5e-14 53.3 0.0 4.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PVD24194.1 - 1.5e-22 79.9 0.0 2.7e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24194.1 - 4e-21 74.9 0.0 5.6e-16 58.4 0.0 2.5 1 1 1 2 2 2 2 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 PVD24194.1 - 1.9e-15 58.1 0.0 3.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24195.1 - 1.6e-28 98.7 0.0 3.6e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PVD24195.1 - 1.8e-24 86.2 0.1 2.9e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD24195.1 - 8.6e-13 49.5 0.0 1.4e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24196.1 - 3.7e-26 91.1 0.0 7e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PVD24196.1 - 7e-15 55.2 0.1 7.9e-14 51.8 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD24196.1 - 6.7e-08 33.7 0.1 1.3e-06 29.5 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PVD24197.1 - 5.6e-27 93.8 0.0 1.2e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PVD24197.1 - 2.9e-21 75.8 0.1 4.3e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD24197.1 - 4.2e-12 47.3 0.0 6.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2013 PF09431.10 PVD24201.1 - 6.5e-27 94.4 0.8 1.9e-26 92.9 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) SH3_9 PF14604.6 PVD24201.1 - 3.6e-10 39.5 0.0 1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD24201.1 - 1.7e-08 33.9 0.0 3.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD24201.1 - 1.5e-07 31.0 0.0 3.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 PVD24201.1 - 0.023 15.1 0.0 0.075 13.5 0.0 1.8 1 0 0 1 1 1 0 Helically-extended SH3 domain FXR_C3 PF16097.5 PVD24201.1 - 0.17 12.6 2.3 2.1 9.1 0.1 3.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 TPT PF03151.16 PVD24202.1 - 8.7e-18 64.7 16.0 9.9e-18 64.5 16.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD24202.1 - 5.3e-07 29.9 26.7 0.002 18.3 9.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family WBP-1 PF11669.8 PVD24202.1 - 0.097 13.3 0.1 0.28 11.8 0.1 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 PrmA PF06325.13 PVD24203.1 - 1.8e-08 34.1 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5_C PF17286.2 PVD24203.1 - 8.8e-07 29.0 0.2 1.7e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 PVD24203.1 - 3.8e-06 27.5 0.0 1.3e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 PVD24203.1 - 4.8e-06 26.5 0.1 7.9e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 PVD24203.1 - 9.1e-05 22.3 0.0 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PVD24203.1 - 0.00012 21.7 0.2 0.00023 20.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PVD24203.1 - 0.00016 21.7 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PVD24203.1 - 0.00021 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 PVD24203.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.16 PVD24203.1 - 0.0057 16.4 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 PVD24203.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 PVD24203.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_M90 PF06167.12 PVD24203.1 - 0.039 13.6 0.1 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 GidB PF02527.15 PVD24203.1 - 0.057 12.7 1.2 1 8.6 0.3 2.7 1 1 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.11 PVD24203.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 PVD24203.1 - 0.12 13.1 0.0 0.46 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RPN7 PF10602.9 PVD24204.1 - 7.3e-60 201.6 2.3 1.2e-59 200.9 2.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PVD24204.1 - 1.8e-17 63.8 0.1 9.3e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 PCI domain Enkurin PF13864.6 PVD24204.1 - 0.0094 16.4 2.1 0.053 13.9 2.2 2.1 2 0 0 2 2 2 1 Calmodulin-binding L31 PF09784.9 PVD24204.1 - 0.017 15.5 0.2 0.047 14.1 0.2 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF4363 PF14276.6 PVD24204.1 - 0.14 12.3 2.4 0.23 11.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Aldedh PF00171.22 PVD24205.1 - 1e-155 518.8 0.5 4e-154 513.5 0.5 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 PVD24205.1 - 2.5e-42 144.7 0.0 4.8e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PVD24205.1 - 6.2e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 PVD24205.1 - 2.6e-05 24.5 0.0 6.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 PVD24205.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DAGK_cat PF00781.24 PVD24207.1 - 1.5e-26 92.5 0.0 3.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FAM76 PF16046.5 PVD24207.1 - 0.049 13.0 11.2 0.21 10.9 11.2 2.0 1 0 0 1 1 1 0 FAM76 protein MscS_TM PF12794.7 PVD24207.1 - 3.5 6.4 7.9 8.1 5.2 7.9 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nuc_sug_transp PF04142.15 PVD24208.1 - 3.2e-127 424.0 24.4 3.8e-127 423.8 24.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PVD24208.1 - 2.1e-05 23.9 18.5 3.1e-05 23.3 17.9 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PVD24208.1 - 9e-05 22.7 32.6 0.0015 18.7 11.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 PVD24208.1 - 0.022 14.0 25.4 0.038 13.2 25.4 1.4 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport TPT PF03151.16 PVD24208.1 - 2.7 7.3 25.8 0.13 11.6 4.6 3.2 2 2 1 3 3 3 0 Triose-phosphate Transporter family DUF202 PF02656.15 PVD24208.1 - 5.5 7.5 11.0 0.8 10.2 2.0 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF202) CHCH PF06747.13 PVD24209.1 - 1.8e-08 34.3 4.9 1.8e-08 34.3 4.9 1.8 2 0 0 2 2 2 1 CHCH domain Urocanase PF01175.18 PVD24210.1 - 1.1e-85 286.5 0.1 2.9e-85 285.2 0.0 1.7 2 0 0 2 2 2 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 PVD24210.1 - 7.9e-79 263.7 4.6 1.5e-78 262.8 4.6 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 PVD24210.1 - 1.7e-57 192.6 0.4 2.2e-56 189.0 0.0 2.5 3 0 0 3 3 3 1 Urocanase N-terminal domain NUDIX PF00293.28 PVD24211.1 - 1.1e-07 31.9 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 PVD24211.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase FGE-sulfatase PF03781.16 PVD24212.1 - 5.6e-85 285.0 6.1 7.7e-85 284.6 6.1 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 SET PF00856.28 PVD24213.1 - 8.3e-21 75.1 0.2 1.6e-18 67.7 0.1 3.1 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 PVD24213.1 - 1.8e-09 38.2 10.7 1.8e-09 38.2 10.7 3.3 4 0 0 4 4 4 1 Pre-SET motif CxC1 PF18802.1 PVD24213.1 - 4.9e-09 36.3 0.1 4.9e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 PVD24213.1 - 1.1e-08 35.1 0.0 1.1e-08 35.1 0.0 2.3 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases Glyco_hydro_20 PF00728.22 PVD24214.1 - 4.1e-93 312.6 0.0 5.2e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 PVD24214.1 - 4.8e-25 88.1 0.0 1.3e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 PVD24214.1 - 3e-23 81.6 0.1 8.7e-23 80.1 0.0 1.9 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 PVD24214.1 - 4.3e-13 50.1 0.0 7.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GRDP-like PF07173.12 PVD24215.1 - 5.3e-49 166.5 4.2 7e-39 133.7 0.8 3.2 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like Alpha_L_fucos PF01120.17 PVD24216.1 - 1.3e-117 393.2 5.2 1.7e-117 392.8 5.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PVD24216.1 - 4.8e-25 87.9 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain zf-MYND PF01753.18 PVD24217.1 - 2.2e-10 40.5 20.6 5.7e-10 39.1 20.6 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 PVD24217.1 - 2.8 7.9 8.9 6.7 6.7 8.9 1.6 1 0 0 1 1 1 0 HIT zinc finger Sulfotransfer_3 PF13469.6 PVD24218.1 - 6.7e-12 46.3 1.2 5.2e-09 36.8 1.2 3.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD24218.1 - 1.8e-11 44.0 0.1 5.9e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 Sulfotransferase domain DUF3270 PF11674.8 PVD24218.1 - 0.14 12.4 0.3 0.28 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) B12D PF06522.11 PVD24219.1 - 0.066 13.0 0.1 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Sulfotransfer_3 PF13469.6 PVD24220.1 - 3.7e-10 40.6 0.3 4e-09 37.2 0.3 2.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD24220.1 - 4.9e-08 32.8 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD24221.1 - 1.1e-10 42.2 0.2 1.5e-08 35.3 0.2 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD24221.1 - 4.5e-10 39.5 0.0 1.8e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 PVD24222.1 - 2.7e-05 23.8 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD24224.1 - 2.2e-11 44.5 6.0 1.2e-06 29.1 0.0 3.3 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD24224.1 - 1.5e-10 41.0 0.1 3.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain SpoIIIAH PF12685.7 PVD24224.1 - 0.37 10.6 18.3 4.1 7.2 13.7 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein Astro_capsid_p PF12226.8 PVD24224.1 - 1.8 7.7 9.2 2.6 7.1 9.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 PVD24224.1 - 7.8 4.7 9.0 15 3.7 9.0 1.4 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 PVD24224.1 - 8.8 6.0 9.9 1.3e+02 2.2 0.0 2.4 2 0 0 2 2 2 0 FAM176 family SEFIR PF08357.11 PVD24225.1 - 1.7e-08 34.9 0.1 5.5e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 SEFIR domain DAG1 PF05454.11 PVD24225.1 - 0.0048 16.3 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) LRR_8 PF13855.6 PVD24228.1 - 4.9e-67 221.6 67.3 1.1e-08 34.7 0.7 14.2 8 4 7 15 15 15 13 Leucine rich repeat TIR PF01582.20 PVD24228.1 - 1.7e-40 138.6 0.4 7.3e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 TIR domain TIR_2 PF13676.6 PVD24228.1 - 4.4e-35 120.9 0.2 7.2e-17 62.1 0.1 2.7 2 0 0 2 2 2 2 TIR domain LRR_4 PF12799.7 PVD24228.1 - 1.1e-32 111.5 58.3 0.0011 19.3 0.2 15.6 12 4 4 16 16 16 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24228.1 - 4.4e-20 72.0 6.7 7.4e-07 29.2 0.0 6.0 4 2 1 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD24228.1 - 4e-11 42.7 17.6 0.39 10.2 0.3 7.7 4 2 1 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 PVD24228.1 - 2.1e-08 33.6 42.3 0.51 11.1 0.2 16.3 19 0 0 19 19 16 2 Leucine Rich Repeat DUF1863 PF08937.11 PVD24228.1 - 9.8e-07 29.1 0.0 0.031 14.6 0.0 3.3 2 2 1 3 3 3 2 MTH538 TIR-like domain (DUF1863) TPKR_C2 PF16920.5 PVD24228.1 - 0.098 12.8 13.5 0.28 11.4 0.6 3.4 4 0 0 4 4 4 0 Tyrosine-protein kinase receptor C2 Ig-like domain SEO_N PF14576.6 PVD24228.1 - 0.14 11.3 2.0 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 Sieve element occlusion N-terminus LRR_6 PF13516.6 PVD24228.1 - 3.5 7.9 43.3 15 5.9 0.0 13.8 16 0 0 16 16 15 0 Leucine Rich repeat LRR_8 PF13855.6 PVD24229.1 - 6.7e-37 125.1 33.8 1.8e-10 40.4 1.4 7.4 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 PVD24229.1 - 4.6e-20 71.4 33.7 0.0018 18.6 0.1 7.5 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD24229.1 - 1.2e-19 70.8 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24229.1 - 1.2e-16 61.3 0.0 3.1e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD24229.1 - 3.7e-10 39.6 13.9 0.072 12.6 0.7 4.5 2 1 1 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 PVD24229.1 - 6.1e-10 39.1 3.2 3.5e-05 23.8 0.0 3.6 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF1863 PF08937.11 PVD24229.1 - 0.00075 19.8 0.0 0.0021 18.4 0.0 1.7 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 PVD24229.1 - 0.00085 19.5 24.8 33 5.6 0.0 10.1 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD24229.1 - 0.0021 18.0 21.8 3.1 8.1 0.2 8.4 9 0 0 9 9 9 1 Leucine Rich repeat TPKR_C2 PF16920.5 PVD24229.1 - 0.89 9.7 3.7 0.6 10.3 0.6 2.5 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain TIR PF01582.20 PVD24230.1 - 3.2e-19 69.4 0.1 8.2e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 PVD24230.1 - 5e-18 65.8 0.1 9.4e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 PVD24230.1 - 0.0015 18.8 0.0 0.0084 16.4 0.0 2.3 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) MMU163 PF17119.5 PVD24230.1 - 0.53 9.4 1.7 0.89 8.7 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis LRR_8 PF13855.6 PVD24231.1 - 4e-32 109.8 30.5 2.2e-09 37.0 4.1 7.2 4 2 2 7 7 7 7 Leucine rich repeat TIR PF01582.20 PVD24231.1 - 6.2e-19 68.5 0.2 1.1e-18 67.7 0.2 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24231.1 - 1.3e-17 64.5 0.1 2.6e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD24231.1 - 1.5e-12 47.5 40.9 0.0028 18.0 3.3 8.8 4 2 3 9 9 9 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24231.1 - 6.5e-11 42.3 7.6 2.3e-08 34.1 0.4 4.2 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD24231.1 - 0.00048 19.7 13.5 0.1 12.1 0.3 4.3 1 1 2 4 4 4 3 Leucine-rich repeat DUF1863 PF08937.11 PVD24231.1 - 0.011 16.0 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TPKR_C2 PF16920.5 PVD24231.1 - 0.047 13.8 1.8 0.12 12.6 0.3 2.5 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 PVD24231.1 - 0.11 13.1 29.2 2 9.3 0.7 9.0 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD24231.1 - 8.3 6.8 25.0 19 5.6 0.1 9.0 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 PVD24232.1 - 5.9e-32 109.2 30.7 7.5e-06 25.6 0.5 7.1 5 2 1 6 6 6 6 Leucine rich repeat TIR PF01582.20 PVD24232.1 - 6.8e-19 68.3 0.2 1.4e-18 67.3 0.2 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24232.1 - 6.9e-18 65.4 0.2 1.8e-17 64.0 0.1 1.7 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 PVD24232.1 - 6.1e-12 45.6 44.6 0.0066 16.8 1.6 9.2 3 2 5 10 10 10 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24232.1 - 1.2e-11 44.7 6.3 3.2e-08 33.6 1.1 3.9 2 2 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD24232.1 - 4.1e-06 26.4 13.8 0.024 14.2 0.4 4.7 1 1 3 5 5 5 4 Leucine-rich repeat DUF1863 PF08937.11 PVD24232.1 - 0.00024 21.4 0.0 0.00082 19.7 0.0 1.8 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 PVD24232.1 - 0.039 14.5 20.5 36 5.5 0.2 8.5 7 1 0 7 7 7 0 Leucine Rich Repeat TPKR_C2 PF16920.5 PVD24232.1 - 0.088 13.0 0.3 0.088 13.0 0.3 2.3 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_8 PF13855.6 PVD24233.1 - 4.1e-34 116.2 32.6 2.7e-08 33.5 0.3 7.1 4 2 3 7 7 7 7 Leucine rich repeat TIR PF01582.20 PVD24233.1 - 6.7e-20 71.6 0.1 1.5e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24233.1 - 2.4e-18 66.9 0.1 5.9e-18 65.6 0.1 1.7 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 PVD24233.1 - 1.7e-12 47.3 37.8 0.0052 17.2 1.0 9.4 3 3 6 10 10 10 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24233.1 - 3.2e-10 40.1 9.2 8.7e-08 32.2 1.1 4.3 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD24233.1 - 6.8e-06 25.7 9.3 0.013 15.0 0.6 3.8 1 1 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 PVD24233.1 - 0.0071 16.3 19.6 19 5.6 0.1 9.0 9 0 0 9 9 9 1 Leucine Rich repeat DUF1863 PF08937.11 PVD24233.1 - 0.0092 16.3 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 PVD24233.1 - 1.1 10.1 20.2 53 4.9 0.5 8.7 8 0 0 8 8 8 0 Leucine Rich Repeat ThiF PF00899.21 PVD24234.1 - 2.6e-114 380.6 0.0 1.7e-75 253.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 PVD24234.1 - 2.5e-90 302.8 0.1 5.6e-90 301.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 PVD24234.1 - 1.9e-36 124.6 0.4 4e-36 123.6 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 PVD24234.1 - 4e-32 110.2 0.4 9e-32 109.1 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 PVD24234.1 - 1.4e-23 82.9 0.6 3.7e-23 81.5 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle End_beta_barrel PF12195.8 PVD24234.1 - 0.16 11.9 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase PAZ PF02170.22 PVD24234.1 - 0.16 11.8 0.4 0.35 10.7 0.4 1.5 1 0 0 1 1 1 0 PAZ domain E2_bind PF08825.10 PVD24234.1 - 0.17 12.1 1.1 0.34 11.1 0.4 1.9 2 0 0 2 2 2 0 E2 binding domain LRR_8 PF13855.6 PVD24235.1 - 4.7e-34 116.0 23.7 8.6e-08 31.8 3.0 7.4 5 2 3 8 8 8 8 Leucine rich repeat TIR PF01582.20 PVD24235.1 - 6.6e-20 71.6 0.1 1.1e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24235.1 - 2e-17 63.9 0.1 4e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD24235.1 - 4.7e-14 52.3 29.6 0.001 19.4 0.9 8.9 3 2 9 12 12 12 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD24235.1 - 1.5e-08 34.7 0.8 1.4e-06 28.3 0.1 3.2 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD24235.1 - 9.6e-08 31.7 8.1 0.16 11.5 0.4 4.8 2 1 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 PVD24235.1 - 0.00032 20.5 17.2 11 6.4 0.1 9.4 10 0 0 10 10 10 1 Leucine Rich repeat DUF1863 PF08937.11 PVD24235.1 - 0.004 17.5 0.0 0.016 15.5 0.0 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 PVD24235.1 - 0.27 11.9 21.7 23 6.0 0.3 8.8 10 0 0 10 10 10 0 Leucine Rich Repeat TPKR_C2 PF16920.5 PVD24235.1 - 2.1 8.6 6.0 0.32 11.2 1.3 2.1 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Cation_ATPase_C PF00689.21 PVD24236.1 - 7.2e-43 146.4 3.7 7.2e-43 146.4 3.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PVD24236.1 - 1.2e-32 112.9 4.7 2.5e-25 89.0 0.4 3.6 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 PVD24236.1 - 6.9e-18 64.5 0.0 1.6e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ATP_Ca_trans_C PF12424.8 PVD24236.1 - 8.8e-15 54.9 0.5 8.8e-15 54.9 0.5 2.2 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase_N PF00690.26 PVD24236.1 - 9.1e-15 54.1 0.0 2.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PVD24236.1 - 3.5e-14 53.6 0.1 5.6e-10 39.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PVD24236.1 - 4e-06 26.7 0.2 0.00025 20.9 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UPF0016 PF01169.19 PVD24236.1 - 0.47 10.8 3.1 0.43 10.9 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 TPR_2 PF07719.17 PVD24238.1 - 1.8e-14 52.6 1.5 0.001 19.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD24238.1 - 3.3e-11 42.5 0.7 4.5e-05 23.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD24238.1 - 1.2e-10 41.2 3.6 0.0043 17.8 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD24238.1 - 2.3e-10 40.9 0.5 4.2e-07 30.5 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD24238.1 - 7.3e-09 35.2 0.2 0.00043 20.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD24238.1 - 8e-09 35.9 3.6 0.00017 22.0 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD24238.1 - 2.4e-08 33.8 0.2 0.12 12.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Cupin_8 PF13621.6 PVD24238.1 - 2.4e-07 30.8 0.0 8.9e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain TPR_12 PF13424.6 PVD24238.1 - 3.4e-07 30.4 3.0 0.012 15.9 1.3 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD24238.1 - 3.7e-07 29.7 0.2 0.0006 19.4 0.1 2.8 2 1 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 PVD24238.1 - 5.5e-06 26.0 0.6 0.26 11.4 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD24238.1 - 0.0001 22.5 0.4 0.0021 18.2 0.5 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 JmjC PF02373.22 PVD24238.1 - 0.00033 21.1 0.0 0.00073 20.0 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase TPR_10 PF13374.6 PVD24238.1 - 0.0013 18.6 3.9 2.9 7.9 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Cupin_4 PF08007.12 PVD24238.1 - 0.0017 17.9 0.1 0.0038 16.7 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein HrpB1_HrpK PF09613.10 PVD24238.1 - 0.0024 17.5 0.2 0.43 10.2 0.1 2.9 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) PsbX PF06596.11 PVD24238.1 - 0.049 13.6 1.4 0.13 12.3 1.4 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) TPR_6 PF13174.6 PVD24238.1 - 0.087 13.5 0.9 4.4 8.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Cupin_1 PF00190.22 PVD24238.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin TPR_4 PF07721.14 PVD24238.1 - 0.22 12.3 1.0 1.9 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 PVD24240.1 - 5e-45 153.0 0.0 6.2e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24240.1 - 1.1e-14 54.7 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24240.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Mito_fiss_Elm1 PF06258.11 PVD24240.1 - 0.024 13.8 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Ras PF00071.22 PVD24241.1 - 8.8e-70 233.5 0.0 2.5e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PVD24241.1 - 2.1e-27 95.7 0.0 3.9e-15 56.1 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24241.1 - 4.2e-08 32.8 0.0 5.4e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD24241.1 - 3.9e-06 26.9 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD24241.1 - 0.0011 18.5 0.2 0.013 15.0 0.0 2.7 2 1 1 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.10 PVD24241.1 - 0.0048 16.4 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PVD24241.1 - 0.014 14.8 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 PVD24241.1 - 0.022 14.2 0.0 0.076 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 PVD24241.1 - 0.13 12.0 0.1 4.5 7.0 0.0 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 PVD24242.1 - 7.4e-52 175.2 0.0 9.3e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24242.1 - 5.4e-22 78.3 0.0 9.3e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24242.1 - 4.7e-06 26.2 0.0 7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD24242.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD24242.1 - 0.032 13.8 0.1 0.23 11.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 PVD24242.1 - 0.045 12.9 0.6 1.9 7.6 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 PVD24242.1 - 0.09 12.2 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein PepSY_TM PF03929.16 PVD24243.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region MAP17 PF15807.5 PVD24243.1 - 0.32 11.2 0.7 0.79 10.0 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pkinase PF00069.25 PVD24245.1 - 2.6e-38 131.9 0.0 4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24245.1 - 9.1e-33 113.6 0.0 1.5e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PVD24245.1 - 0.0005 19.7 0.0 0.91 9.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Death PF00531.22 PVD24245.1 - 0.003 17.7 0.1 0.0062 16.7 0.1 1.5 1 0 0 1 1 1 1 Death domain Kinase-like PF14531.6 PVD24245.1 - 0.13 11.6 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Mito_carr PF00153.27 PVD24246.1 - 4.9e-51 170.6 10.8 3.1e-22 78.3 0.3 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 PVD24246.1 - 0.00077 18.7 0.6 0.0017 17.6 0.6 1.5 1 1 0 1 1 1 1 Gammaproteobacterial serine protease Proteasome PF00227.26 PVD24247.1 - 1.8e-28 99.3 0.1 2e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Death PF00531.22 PVD24248.1 - 0.0089 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Death domain CBFD_NFYB_HMF PF00808.23 PVD24249.1 - 0.0017 18.6 0.1 0.0026 18.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 PVD24250.1 - 8.3e-60 202.4 0.1 1.4e-59 201.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24250.1 - 9.5e-47 159.4 0.1 1.8e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FR47 PF08445.10 PVD24250.1 - 1.8e-12 47.0 0.0 4.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Gly_acyl_tr_N PF06021.11 PVD24250.1 - 4.5e-11 43.2 1.1 3.1e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_1 PF00583.25 PVD24250.1 - 3.9e-08 33.5 0.0 1.2e-07 31.9 0.0 1.9 2 0 0 2 2 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD24250.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD24250.1 - 2.2e-06 28.0 0.0 1.2e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pkinase_fungal PF17667.1 PVD24250.1 - 0.00023 20.1 0.0 0.00023 20.1 0.0 2.9 2 1 0 2 2 1 1 Fungal protein kinase Acetyltransf_3 PF13302.7 PVD24250.1 - 0.00064 20.4 0.0 0.0015 19.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kinase-like PF14531.6 PVD24250.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GNAT_acetyltran PF12746.7 PVD24250.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 PVD24250.1 - 0.0034 17.1 0.0 0.0095 15.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Kdo PF06293.14 PVD24250.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD24250.1 - 0.017 15.0 0.0 3.9 7.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_9 PF13527.7 PVD24250.1 - 0.032 14.3 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 PVD24250.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Haspin_kinase PF12330.8 PVD24250.1 - 0.06 12.3 0.0 0.06 12.3 0.0 1.9 2 0 0 2 2 1 0 Haspin like kinase domain RIO1 PF01163.22 PVD24250.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Myb_DNA-binding PF00249.31 PVD24251.1 - 2.7e-25 88.3 11.8 4.6e-13 49.1 0.1 4.5 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD24251.1 - 1e-15 57.7 17.5 1.7e-08 34.6 0.1 4.3 4 0 0 4 4 4 3 Myb-like DNA-binding domain Atg29_N PF18388.1 PVD24251.1 - 0.025 14.4 2.6 0.077 12.8 2.6 1.8 1 0 0 1 1 1 0 Atg29 N-terminal domain ATP-grasp_2 PF08442.10 PVD24252.1 - 7e-48 162.9 0.3 1.3e-47 162.0 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 PVD24252.1 - 6.3e-25 87.8 0.4 1.1e-24 87.0 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Transglut_core PF01841.19 PVD24254.1 - 1.3e-05 25.6 0.1 2.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily TT_ORF2 PF02957.15 PVD24254.1 - 9.7 7.1 7.1 4.5 8.2 2.4 2.6 2 1 0 2 2 2 0 TT viral ORF2 DUF5320 PF17253.2 PVD24259.1 - 0.0015 19.5 1.2 0.0021 19.1 1.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5320) ToxN_toxin PF13958.6 PVD24259.1 - 0.037 14.3 0.5 0.045 14.0 0.5 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system CPP1-like PF11833.8 PVD24262.1 - 0.16 11.6 0.1 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like OSTbeta PF15048.6 PVD24262.1 - 0.34 11.1 2.3 0.51 10.5 2.3 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Fungal_trans_2 PF11951.8 PVD24262.1 - 0.44 9.3 3.6 0.26 10.1 1.0 1.6 1 1 1 2 2 2 0 Fungal specific transcription factor domain PLN_propep PF16485.5 PVD24267.1 - 0.047 13.4 0.5 0.072 12.8 0.5 1.3 1 0 0 1 1 1 0 Protealysin propeptide SSP160 PF06933.11 PVD24272.1 - 0.11 10.7 2.4 0.13 10.4 2.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SUIM_assoc PF16619.5 PVD24274.1 - 0.43 10.7 23.5 0.74 9.9 23.5 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PDGF_N PF04692.13 PVD24274.1 - 0.44 11.3 4.5 0.52 11.1 4.5 1.1 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Spt20 PF12090.8 PVD24274.1 - 0.73 9.4 19.9 0.76 9.3 19.9 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 PVD24274.1 - 0.73 9.0 18.1 0.81 8.8 18.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MscS_TM PF12794.7 PVD24274.1 - 0.75 8.6 5.1 0.76 8.6 5.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Folate_carrier PF01770.18 PVD24274.1 - 1.5 7.5 4.8 1.5 7.5 4.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF2572 PF10833.8 PVD24274.1 - 1.9 8.2 8.9 1.8 8.3 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Inj_translocase PF16928.5 PVD24274.1 - 2.4 7.6 14.3 2.6 7.4 14.3 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome DUF2722 PF10846.8 PVD24274.1 - 2.6 6.9 15.7 2.6 6.9 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 PVD24274.1 - 3.6 6.2 6.6 3.4 6.4 6.6 1.0 1 0 0 1 1 1 0 Presenilin Pex26 PF07163.12 PVD24274.1 - 4.1 6.6 7.2 4 6.7 7.2 1.0 1 0 0 1 1 1 0 Pex26 protein DUF4175 PF13779.6 PVD24274.1 - 4.2 5.2 10.7 3.8 5.3 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3464 PF11947.8 PVD24274.1 - 6.2 6.6 6.4 6.5 6.5 6.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4834 PF16118.5 PVD24274.1 - 6.6 7.8 11.8 7.4 7.6 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Tmemb_40 PF10160.9 PVD24276.1 - 3.1e-66 223.4 16.6 4e-66 223.1 16.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein DRMBL PF07522.14 PVD24277.1 - 4.6e-12 46.1 0.2 1.5e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 PVD24277.1 - 0.0024 17.4 0.1 0.006 16.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EB PF01683.18 PVD24278.1 - 1.2e-12 47.9 121.9 0.054 13.8 9.8 8.6 3 2 5 8 8 8 7 EB module EGF PF00008.27 PVD24278.1 - 1.4e-05 25.3 104.0 0.087 13.2 5.5 9.3 8 0 0 8 8 8 5 EGF-like domain S_locus_glycop PF00954.20 PVD24278.1 - 0.00062 20.3 93.0 0.01 16.4 3.4 8.1 8 0 0 8 8 8 5 S-locus glycoprotein domain cEGF PF12662.7 PVD24278.1 - 0.0064 16.4 65.2 1.2 9.1 1.8 9.2 8 0 0 8 8 8 7 Complement Clr-like EGF-like EGF_2 PF07974.13 PVD24278.1 - 0.015 15.7 129.4 0.18 12.2 7.2 10.2 8 3 0 8 8 8 0 EGF-like domain SopA_C PF13979.6 PVD24278.1 - 0.015 15.0 11.0 2.5 7.8 0.1 4.9 3 2 2 5 5 5 0 SopA-like catalytic domain EGF_3 PF12947.7 PVD24278.1 - 0.036 14.3 112.9 0.38 11.0 3.5 11.0 6 2 3 9 9 9 0 EGF domain Nitro_FeMo-Co PF02579.17 PVD24278.1 - 0.22 11.9 1.7 5.2 7.5 0.2 2.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor DUF4490 PF14892.6 PVD24279.1 - 6.6e-38 128.9 1.3 7.4e-38 128.8 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CLCA PF08434.11 PVD24280.1 - 5.8e-74 248.8 0.0 8.1e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 PVD24280.1 - 5.2e-21 75.7 0.1 8.9e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24280.1 - 1.1e-13 51.8 0.1 2.9e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD24280.1 - 4e-08 32.9 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 PVD24280.1 - 1.3e-07 31.7 0.1 7.6e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.11 PVD24280.1 - 4.9e-07 29.2 0.0 1.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) CLCA PF08434.11 PVD24281.1 - 7.6e-58 195.9 0.5 2.8e-56 190.8 0.5 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 PVD24281.1 - 2.4e-16 60.5 0.0 4.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24281.1 - 7.4e-13 49.1 0.0 2.3e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD24281.1 - 3.3e-08 33.2 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 PVD24281.1 - 0.026 13.7 0.1 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Rhabdo_glycop PF00974.18 PVD24281.1 - 0.054 11.9 0.0 0.083 11.3 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TMEM154 PF15102.6 PVD24281.1 - 0.06 13.2 0.4 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family TMEM132D_C PF15706.5 PVD24281.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term CLCA PF08434.11 PVD24282.1 - 6e-53 179.9 2.6 5.3e-51 173.5 2.6 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 PVD24282.1 - 4.1e-18 66.2 0.2 8.4e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24282.1 - 1.1e-12 48.5 0.2 4.8e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD24282.1 - 1.9e-07 30.7 0.1 3.6e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 PVD24282.1 - 0.031 13.5 0.0 0.1 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1194) VWA_3 PF13768.6 PVD24282.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Stevor PF17410.2 PVD24282.1 - 0.19 11.3 0.6 0.35 10.4 0.6 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CLCA PF08434.11 PVD24283.1 - 3e-44 151.3 0.5 4e-44 151.0 0.0 1.4 2 0 0 2 2 2 1 Calcium-activated chloride channel N terminal DUF809 PF05663.11 PVD24283.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF809) U3_snoRNA_assoc PF08297.11 PVD24283.1 - 6.9 7.5 13.6 2.1 9.1 10.7 1.7 2 0 0 2 2 2 0 U3 snoRNA associated CLCA PF08434.11 PVD24285.1 - 7.1e-37 127.2 1.5 9.4e-27 94.0 0.0 2.2 1 1 1 2 2 2 2 Calcium-activated chloride channel N terminal VWA PF00092.28 PVD24285.1 - 2e-14 54.2 0.3 4.5e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24285.1 - 3.7e-11 43.6 0.1 1.5e-10 41.7 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD24285.1 - 1e-05 25.1 0.2 3.1e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DUF3377 PF11857.8 PVD24285.1 - 0.0011 18.9 0.4 0.0034 17.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF1194 PF06707.11 PVD24285.1 - 0.014 14.6 0.1 0.032 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Hydrolase_4 PF12146.8 PVD24288.1 - 4.3e-74 248.8 0.0 5e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD24288.1 - 3.7e-17 62.8 0.4 3.5e-11 43.3 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD24288.1 - 3.3e-14 54.0 0.1 4e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PVD24288.1 - 0.00013 21.5 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 PVD24288.1 - 0.00013 21.7 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 PVD24288.1 - 0.00081 19.2 0.0 0.064 13.0 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 PVD24288.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 PVD24288.1 - 0.0021 17.9 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 PVD24288.1 - 0.0023 18.1 0.1 0.0035 17.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 PVD24288.1 - 0.0035 16.9 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 PVD24288.1 - 0.019 13.5 0.5 0.59 8.6 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 PVD24288.1 - 0.03 14.0 0.1 0.13 11.9 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 PVD24288.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PVD24288.1 - 0.096 12.5 0.0 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TTL PF03133.15 PVD24288.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family COG6 PF06419.11 PVD24289.1 - 1.1e-198 661.4 17.0 1.7e-132 442.8 0.3 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 Sec34 PF04136.15 PVD24289.1 - 0.00032 20.6 3.5 0.00032 20.6 3.5 2.8 2 1 1 3 3 3 1 Sec34-like family HMMR_N PF15905.5 PVD24289.1 - 0.0043 16.6 12.4 0.0068 15.9 12.4 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal PRONE PF03759.13 PVD24289.1 - 0.017 13.9 1.8 0.028 13.3 1.8 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) YabA PF06156.13 PVD24289.1 - 0.6 10.8 5.9 0.24 12.1 1.0 2.8 1 1 2 3 3 3 0 Initiation control protein YabA DUF489 PF04356.12 PVD24289.1 - 3.3 7.7 8.8 0.31 11.0 0.9 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF489) Muted PF14942.6 PVD24289.1 - 8 6.8 11.8 6.5 7.1 7.0 2.9 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Glyco_hydro_47 PF01532.20 PVD24290.1 - 2e-114 383.0 0.0 3.3e-114 382.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PDZ PF00595.24 PVD24291.1 - 2.5e-80 264.9 0.3 1.8e-14 53.8 0.1 7.2 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 PVD24291.1 - 3.4e-64 212.5 2.5 1.5e-10 40.7 0.0 6.3 6 0 0 6 6 6 6 PDZ domain PDZ_2 PF13180.6 PVD24291.1 - 8.2e-36 122.2 0.1 1.4e-05 25.3 0.0 6.5 6 0 0 6 6 6 6 PDZ domain Tricorn_PDZ PF14685.6 PVD24291.1 - 6.2e-09 35.7 0.6 0.98 9.4 0.0 6.0 6 0 0 6 6 6 3 Tricorn protease PDZ domain GRASP55_65 PF04495.14 PVD24291.1 - 1.3e-08 35.3 0.0 0.14 12.5 0.0 5.3 3 1 2 5 5 5 2 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 PVD24291.1 - 0.082 13.3 0.0 21 5.6 0.0 3.5 4 0 0 4 4 4 0 PDZ domain Androgen_recep PF02166.16 PVD24292.1 - 0.12 11.2 1.3 0.14 10.9 1.3 1.1 1 0 0 1 1 1 0 Androgen receptor 7tm_3 PF00003.22 PVD24296.1 - 1.1e-54 185.7 36.1 7.9e-54 182.9 34.6 2.1 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 PVD24296.1 - 1.5e-14 53.7 17.6 3.7e-14 52.4 17.6 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR ANF_receptor PF01094.28 PVD24296.1 - 0.057 12.5 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region ANF_receptor PF01094.28 PVD24297.1 - 1.5e-91 307.2 0.0 2.1e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD24297.1 - 3.1e-12 46.8 0.2 5e-12 46.1 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SMC_N PF02463.19 PVD24300.1 - 5.6e-53 179.6 54.0 1.4e-51 175.0 54.0 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PVD24300.1 - 6.5e-26 90.9 0.0 1.7e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 PVD24300.1 - 1.4e-16 61.2 11.9 1.4e-16 61.2 11.9 4.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 PVD24300.1 - 2.2e-14 54.4 31.0 2.2e-14 54.4 31.0 7.5 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 PVD24300.1 - 1.6e-11 44.6 0.1 8.4e-08 32.4 0.0 4.3 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD24300.1 - 2.2e-08 33.7 0.0 4.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 PVD24300.1 - 0.0062 16.5 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 PVD24300.1 - 0.052 13.8 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 PVD24300.1 - 0.13 12.5 1.4 6.7 7.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain Flagellin_C PF00700.21 PVD24300.1 - 0.52 10.7 10.5 11 6.5 0.4 4.7 3 2 0 3 3 3 0 Bacterial flagellin C-terminal helical region RIB43A PF05914.12 PVD24301.1 - 3.5e-150 499.9 58.5 3.9e-150 499.8 58.5 1.0 1 0 0 1 1 1 1 RIB43A Fringe PF02434.16 PVD24302.1 - 2.8e-06 26.9 0.1 1.1e-05 25.0 0.1 1.9 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 PVD24302.1 - 0.0011 18.8 0.1 0.012 15.5 0.1 2.0 1 1 1 2 2 2 1 Galactosyltransferase PhoPQ_related PF10142.9 PVD24305.1 - 2.2e-108 362.2 0.2 2.5e-108 362.0 0.2 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein PhoPQ_related PF10142.9 PVD24306.1 - 1.3e-90 303.7 2.6 5.9e-64 216.0 1.5 2.1 1 1 1 2 2 2 2 PhoPQ-activated pathogenicity-related protein PET PF06297.14 PVD24307.1 - 9e-29 99.6 0.2 2.6e-28 98.1 0.2 1.8 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 PVD24307.1 - 3e-26 91.4 46.6 2.9e-11 43.4 4.1 3.7 4 0 0 4 4 4 3 LIM domain zf-ribbon_3 PF13248.6 PVD24307.1 - 0.21 11.1 13.5 1.1 8.8 0.2 5.1 5 0 0 5 5 5 0 zinc-ribbon domain Frag1 PF10277.9 PVD24310.1 - 2e-31 109.3 8.5 2.5e-31 108.9 8.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Sh_2 PF17512.2 PVD24310.1 - 0.075 12.8 0.4 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein YtpI PF14007.6 PVD24310.1 - 3.7 7.7 9.8 0.23 11.6 3.4 2.2 2 0 0 2 2 2 0 YtpI-like protein VEGFR-2_TMD PF17988.1 PVD24310.1 - 4.1 6.9 6.6 1.2 8.7 0.1 2.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Peptidase_S9 PF00326.21 PVD24311.1 - 6.6e-38 130.3 0.0 1.4e-37 129.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PVD24311.1 - 1.3e-09 38.1 0.3 1.6e-05 24.7 0.3 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD24311.1 - 1.4e-06 27.8 0.0 5.2e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 PVD24311.1 - 9.7e-05 21.2 0.0 0.00021 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PVD24311.1 - 0.00014 21.8 0.0 0.00051 20.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold THAP PF05485.12 PVD24311.1 - 0.00099 20.0 0.0 0.0041 18.0 0.0 2.2 1 0 0 1 1 1 1 THAP domain DLH PF01738.18 PVD24311.1 - 0.0015 18.2 0.0 0.026 14.1 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 PVD24311.1 - 0.0026 18.4 0.1 0.0056 17.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 PVD24311.1 - 0.0077 15.1 0.2 0.018 13.8 0.0 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase S28 SIS_2 PF13580.6 PVD24311.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 SIS domain Esterase PF00756.20 PVD24311.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative esterase MRP-S32 PF10210.9 PVD24312.1 - 9.8e-09 35.7 0.1 9.8e-09 35.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Kelch_1 PF01344.25 PVD24313.1 - 3.7e-28 96.9 9.2 7.1e-09 35.1 0.0 6.1 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD24313.1 - 5.8e-26 89.9 7.0 2.9e-06 27.3 1.1 5.8 2 1 3 5 5 5 4 Kelch motif BTB PF00651.31 PVD24313.1 - 7.3e-26 90.6 0.8 3.4e-25 88.4 0.9 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 PVD24313.1 - 7.3e-21 73.3 3.6 4e-05 23.4 0.0 5.8 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 PVD24313.1 - 3e-18 65.6 4.2 1.7e-05 24.8 0.8 5.9 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD24313.1 - 1.6e-14 53.8 10.3 0.00014 22.0 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain BACK PF07707.15 PVD24313.1 - 1.3e-11 44.5 0.1 3.5e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 PVD24313.1 - 2e-10 40.4 3.1 0.011 15.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif BTB_3 PF16017.5 PVD24313.1 - 0.0037 17.4 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF4598 PF15370.6 PVD24314.1 - 1.9e-11 44.4 1.7 1.9e-11 44.4 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) MgtE PF01769.16 PVD24315.1 - 2.3e-51 173.4 25.2 2.1e-28 99.2 1.8 3.6 4 0 0 4 4 4 2 Divalent cation transporter Proton_antipo_N PF00662.20 PVD24315.1 - 2 8.5 6.2 4.3 7.5 0.5 3.0 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus ATG16 PF08614.11 PVD24316.1 - 0.029 14.6 67.4 0.071 13.3 13.7 4.4 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 PVD24316.1 - 0.03 14.8 64.1 0.046 14.2 27.1 4.3 1 1 3 4 4 4 0 Fez1 DUF812 PF05667.11 PVD24316.1 - 0.035 13.0 58.8 0.05 12.5 33.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) HOOK PF05622.12 PVD24316.1 - 0.21 9.7 54.7 0.1 10.8 7.9 3.1 2 1 1 3 3 3 0 HOOK protein Filament PF00038.21 PVD24316.1 - 0.24 11.0 52.4 0.28 10.7 6.0 4.4 3 1 1 4 4 4 0 Intermediate filament protein GAS PF13851.6 PVD24316.1 - 0.29 10.5 66.8 0.12 11.7 9.9 4.3 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 PVD24316.1 - 0.6 8.2 61.2 0.059 11.6 33.3 3.0 1 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 PVD24316.1 - 2.2 7.1 65.0 0.62 8.9 9.8 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein ERM PF00769.19 PVD24316.1 - 3.5 7.4 70.2 0.084 12.7 19.5 3.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2203 PF09969.9 PVD24316.1 - 4.8 7.9 41.3 0.3 11.8 2.9 5.2 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2203) EzrA PF06160.12 PVD24316.1 - 7.7 4.6 47.8 4.5 5.3 15.3 3.5 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 PVD24316.1 - 8.1 7.0 18.4 10 6.6 0.0 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein FHA PF00498.26 PVD24317.1 - 7.4e-17 61.5 0.0 1.5e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain CREPT PF16566.5 PVD24317.1 - 0.00027 21.2 16.9 0.00027 21.2 16.9 3.9 2 1 0 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour Yop-YscD_cpl PF16697.5 PVD24317.1 - 0.00097 19.4 0.0 0.0048 17.2 0.0 2.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3450 PF11932.8 PVD24317.1 - 0.0053 16.1 21.6 0.0053 16.1 21.6 3.9 2 1 2 4 4 3 1 Protein of unknown function (DUF3450) Lebercilin PF15619.6 PVD24317.1 - 0.01 15.5 61.6 0.014 15.1 40.4 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 PVD24317.1 - 0.036 14.3 62.8 0.15 12.3 12.8 4.1 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF2756 PF10956.8 PVD24317.1 - 0.043 14.3 1.5 0.043 14.3 1.5 3.1 3 2 0 3 3 1 0 Protein of unknown function (DUF2756) Rh5 PF18515.1 PVD24317.1 - 0.28 10.4 15.2 0.057 12.7 10.9 1.9 2 0 0 2 2 2 0 Rh5 coiled-coil domain DUF1664 PF07889.12 PVD24317.1 - 0.66 10.0 27.9 0.39 10.8 0.7 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD24317.1 - 1.2 9.2 65.0 0.48 10.5 26.7 4.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 PVD24317.1 - 1.6 9.1 40.3 0.43 11.0 16.6 4.2 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 PVD24317.1 - 2.6 7.1 47.2 0.019 14.1 2.6 3.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 PVD24317.1 - 5.2 5.8 50.0 12 4.6 50.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.21 PVD24317.1 - 6.9 6.2 53.7 93 2.4 31.9 2.7 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 PVD24317.1 - 8.8 5.1 61.0 0.11 11.4 27.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein SPA PF08616.10 PVD24318.1 - 1.8e-16 60.1 0.0 3.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 PVD24318.1 - 1.2e-08 35.1 3.0 4.1e-08 33.4 1.4 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 PVD24318.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 Transport protein Avl9 RAM PF15320.6 PVD24318.1 - 0.066 13.8 0.3 0.14 12.8 0.3 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Lectin_C PF00059.21 PVD24319.1 - 3.8e-10 40.5 1.3 9.1e-07 29.6 0.0 3.4 4 1 0 4 4 4 2 Lectin C-type domain PAN_1 PF00024.26 PVD24319.1 - 4.2e-10 39.4 9.6 0.00015 21.6 0.6 2.6 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PVD24319.1 - 1.7e-05 24.7 7.3 0.02 14.8 0.4 3.2 3 0 0 3 3 3 2 PAN domain MANEC PF07502.14 PVD24319.1 - 0.0063 16.8 6.2 1 9.7 0.2 3.6 3 0 0 3 3 3 2 MANEC domain PAN_3 PF08277.12 PVD24319.1 - 0.12 12.2 8.3 0.54 10.1 0.7 3.1 3 0 0 3 3 3 0 PAN-like domain Lectin_C PF00059.21 PVD24320.1 - 3.9e-09 37.2 0.2 0.00097 19.8 0.0 3.0 3 0 0 3 3 3 2 Lectin C-type domain PAN_1 PF00024.26 PVD24320.1 - 0.00025 20.9 1.7 0.00025 20.9 1.7 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 PVD24320.1 - 0.00065 19.6 0.8 0.0017 18.3 0.8 1.7 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 PVD24320.1 - 0.0033 17.6 0.5 0.73 10.2 0.2 2.5 2 0 0 2 2 2 2 MANEC domain COPI_C PF06957.11 PVD24321.1 - 0.024 13.4 1.8 0.03 13.1 1.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.12 PVD24321.1 - 0.036 12.3 6.3 0.034 12.4 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF35_N PF12172.8 PVD24321.1 - 0.044 13.7 3.1 0.23 11.4 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Nudix_N_2 PF14803.6 PVD24321.1 - 0.089 12.7 2.3 2.3 8.2 0.6 2.5 2 0 0 2 2 2 0 Nudix N-terminal SDA1 PF05285.12 PVD24321.1 - 0.099 12.1 6.0 0.1 12.0 6.0 1.1 1 0 0 1 1 1 0 SDA1 zf-RRN7 PF11781.8 PVD24321.1 - 0.22 11.3 19.3 0.23 11.2 0.8 3.8 3 1 1 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RRN3 PF05327.11 PVD24321.1 - 0.83 8.1 3.7 0.79 8.2 3.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-3CxxC_2 PF17180.4 PVD24322.1 - 4.1e-07 30.6 5.4 4.1e-07 30.6 5.4 1.9 2 0 0 2 2 2 1 Zinc-binding domain zf-3CxxC PF13695.6 PVD24322.1 - 0.024 15.1 3.9 0.024 15.1 3.9 2.1 1 1 1 2 2 2 0 Zinc-binding domain Patatin PF01734.22 PVD24323.1 - 3e-27 96.1 0.0 3e-27 96.1 0.0 5.0 2 1 0 3 3 3 1 Patatin-like phospholipase Herpes_BLLF1 PF05109.13 PVD24323.1 - 2.5e-11 42.4 471.2 0.03 12.3 37.1 12.4 1 1 11 12 12 12 11 Herpes virus major outer envelope glycoprotein (BLLF1) Flu_NS1 PF00600.19 PVD24323.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) zf-ribbon_3 PF13248.6 PVD24323.1 - 0.62 9.6 5.1 2 7.9 5.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain GCV_T PF01571.21 PVD24324.1 - 1.4e-83 280.2 0.0 1.7e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PVD24324.1 - 6.2e-20 70.9 0.0 1.3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain ING PF12998.7 PVD24325.1 - 3.9e-20 72.3 6.8 7e-20 71.5 5.9 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding BAG PF02179.16 PVD24325.1 - 0.0041 17.5 1.8 0.12 12.8 1.8 2.3 1 1 0 1 1 1 1 BAG domain Myosin_tail_1 PF01576.19 PVD24325.1 - 0.0054 14.6 12.1 0.0069 14.3 12.1 1.1 1 0 0 1 1 1 1 Myosin tail DUF445 PF04286.12 PVD24325.1 - 0.039 13.8 1.2 0.048 13.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mucin15 PF15672.5 PVD24325.1 - 0.19 11.2 8.8 0.27 10.7 8.8 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Pap_E4 PF02711.14 PVD24325.1 - 0.61 11.1 9.2 7.1 7.7 3.9 2.5 2 0 0 2 2 2 0 E4 protein DUF4200 PF13863.6 PVD24325.1 - 1.8 9.0 9.5 3.2 8.2 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HSCB_C PF07743.13 PVD24325.1 - 7.3 7.2 7.9 2.5 8.7 1.8 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain AIRS PF00586.24 PVD24326.1 - 1.4e-10 41.7 0.1 2.6e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 PVD24326.1 - 1.8e-05 24.9 0.2 0.13 12.4 0.1 2.3 1 1 1 2 2 2 2 AIR synthase related protein, C-terminal domain IMPDH PF00478.25 PVD24327.1 - 1.2e-129 432.3 2.4 1.5e-129 432.0 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 PVD24327.1 - 1.1e-13 51.3 1.2 3.5e-09 36.5 0.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase CBS PF00571.28 PVD24327.1 - 4.7e-11 43.0 0.1 7.2e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 PVD24327.1 - 5.7e-11 42.0 0.5 1.1e-10 41.2 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 PVD24327.1 - 1.2e-05 24.9 0.7 0.00023 20.7 0.1 2.2 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 PVD24327.1 - 0.00017 21.0 0.5 0.0003 20.2 0.5 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 PVD24327.1 - 0.0032 16.7 1.3 0.0054 15.9 1.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldolase PF01081.19 PVD24327.1 - 0.0074 15.7 0.3 0.43 10.0 0.0 2.9 3 0 0 3 3 3 1 KDPG and KHG aldolase DUF561 PF04481.12 PVD24327.1 - 0.011 14.9 0.8 0.026 13.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DHO_dh PF01180.21 PVD24327.1 - 0.018 14.2 3.0 0.021 14.1 0.3 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Dus PF01207.17 PVD24327.1 - 0.024 13.8 0.7 0.089 11.9 0.0 1.9 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 PVD24327.1 - 0.062 12.7 0.5 0.43 10.0 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dpy19 PF10034.9 PVD24327.1 - 0.066 11.4 0.0 0.25 9.5 0.0 1.7 2 0 0 2 2 2 0 Q-cell neuroblast polarisation NanE PF04131.14 PVD24327.1 - 0.096 11.9 1.0 12 5.0 0.1 2.6 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 PVD24327.1 - 0.15 11.2 0.2 6.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Neurexophilin PF06312.12 PVD24329.1 - 0.00021 20.9 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin EF-hand_7 PF13499.6 PVD24329.1 - 0.045 14.2 0.5 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Ig_2 PF13895.6 PVD24330.1 - 1.2e-05 25.5 0.1 0.0016 18.7 0.0 3.2 1 1 2 3 3 3 1 Immunoglobulin domain I-set PF07679.16 PVD24330.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 PVD24330.1 - 0.0078 16.2 0.2 0.22 11.6 0.0 2.9 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain V-set PF07686.17 PVD24330.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD24330.1 - 0.028 15.0 3.8 0.14 12.8 0.0 3.2 3 2 0 3 3 3 0 Immunoglobulin domain MarC PF01914.17 PVD24330.1 - 0.076 12.4 0.1 0.21 11.0 0.1 1.6 1 1 0 1 1 1 0 MarC family integral membrane protein V-set PF07686.17 PVD24331.1 - 0.00065 19.8 0.1 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD24331.1 - 0.0025 18.1 0.0 0.037 14.4 0.0 2.6 2 1 1 3 3 3 1 Immunoglobulin domain DUF885 PF05960.11 PVD24331.1 - 0.016 14.9 3.1 0.027 14.1 3.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ig_3 PF13927.6 PVD24331.1 - 0.017 15.7 0.0 0.9 10.2 0.0 3.3 2 1 0 2 2 2 0 Immunoglobulin domain Protocadherin PF08374.11 PVD24331.1 - 0.053 13.5 3.6 0.14 12.1 0.3 2.3 1 1 1 2 2 2 0 Protocadherin Izumo-Ig PF16706.5 PVD24331.1 - 0.063 13.3 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain ig PF00047.25 PVD24331.1 - 0.071 13.3 0.9 36 4.6 0.4 3.4 2 1 0 2 2 2 0 Immunoglobulin domain DUF2663 PF10864.8 PVD24331.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Syndecan PF01034.20 PVD24331.1 - 0.17 11.8 5.1 0.12 12.3 2.1 2.2 2 0 0 2 2 2 0 Syndecan domain Filament PF00038.21 PVD24333.1 - 0.015 14.9 9.0 0.015 14.9 9.0 1.8 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 PVD24333.1 - 0.017 15.3 6.8 0.12 12.6 0.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 PVD24333.1 - 0.019 13.9 13.4 0.03 13.2 13.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Zein-binding PF04576.15 PVD24333.1 - 0.025 14.8 10.7 0.23 11.7 2.8 2.5 1 1 1 2 2 2 0 Zein-binding Bacillus_HBL PF05791.11 PVD24333.1 - 0.096 12.5 1.6 0.14 11.9 1.6 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.8 PVD24333.1 - 0.11 12.6 6.4 0.17 12.0 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 PVD24333.1 - 0.21 11.1 7.5 0.27 10.8 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4515 PF14988.6 PVD24333.1 - 0.31 10.8 15.0 0.04 13.8 9.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) ING PF12998.7 PVD24333.1 - 0.36 11.5 8.2 0.6 10.7 4.6 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PKcGMP_CC PF16808.5 PVD24333.1 - 0.4 10.6 12.0 2 8.3 1.1 4.1 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ERM PF00769.19 PVD24333.1 - 0.51 10.1 19.2 0.32 10.8 17.5 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4094 PF13334.6 PVD24333.1 - 0.52 10.8 5.2 6 7.4 3.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 PVD24333.1 - 0.57 10.8 12.6 1.1 9.9 4.3 3.5 1 1 2 3 3 3 0 SlyX Nbl1_Borealin_N PF10444.9 PVD24333.1 - 1.5 8.5 7.0 10 5.9 1.5 2.5 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal Cnn_1N PF07989.11 PVD24333.1 - 2.1 8.6 11.1 2 8.7 7.3 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF16 PF01519.16 PVD24333.1 - 2.2 8.8 5.8 12 6.5 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FapA PF03961.13 PVD24333.1 - 2.5 6.6 7.9 4.7 5.7 7.8 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 PVD24333.1 - 3 7.0 6.9 2.4 7.3 4.7 1.7 1 1 1 2 2 2 0 TMPIT-like protein YabA PF06156.13 PVD24333.1 - 4.4 8.0 6.5 7.5 7.2 3.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 PVD24333.1 - 4.4 5.1 4.6 5.5 4.8 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFP_35_N PF07334.13 PVD24333.1 - 4.6 7.4 9.4 2.6 8.2 0.9 3.3 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus M PF02370.16 PVD24333.1 - 7.7 7.5 10.2 12 6.9 0.2 4.4 4 0 0 4 4 4 0 M protein repeat DivIC PF04977.15 PVD24333.1 - 8.4 6.2 15.1 45 3.9 0.1 3.4 1 1 2 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 PVD24333.1 - 8.7 6.7 17.9 3.9 7.8 9.2 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF3782 PF12644.7 PVD24333.1 - 9.5 6.5 7.6 5.2 7.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) STIMATE PF12400.8 PVD24334.1 - 8.7e-33 113.5 8.6 1.4e-32 112.9 8.6 1.3 1 0 0 1 1 1 1 STIMATE family DUF763 PF05559.11 PVD24334.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) HemY_N PF07219.13 PVD24334.1 - 1.2 9.4 3.3 8 6.7 0.0 2.8 3 0 0 3 3 3 0 HemY protein N-terminus MBT PF02820.18 PVD24335.1 - 3.2e-85 280.5 1.2 6.2e-22 77.7 0.1 4.4 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 PVD24335.1 - 1.6e-36 125.2 1.0 4.1e-36 123.9 1.0 1.7 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 PVD24335.1 - 1.2e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD24335.1 - 2.7e-06 27.4 0.0 5.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Agenet PF05641.12 PVD24335.1 - 0.0059 17.0 0.3 5.2 7.6 0.0 3.5 4 0 0 4 4 4 1 Agenet domain SAM_PNT PF02198.16 PVD24335.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Myb_DNA-binding PF00249.31 PVD24336.1 - 1e-17 64.0 5.9 3.1e-11 43.3 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.31 PVD24336.1 - 8.1e-17 61.1 2.8 1.1e-16 60.7 0.5 2.7 2 0 0 2 2 2 1 DnaJ domain RAC_head PF16717.5 PVD24336.1 - 6.3e-16 59.1 13.6 6.3e-16 59.1 13.6 4.3 6 1 0 6 6 6 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.6 PVD24336.1 - 2e-12 47.2 2.8 8.1e-08 32.4 0.3 3.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Peptidase_S66 PF02016.15 PVD24336.1 - 3.1 7.9 4.9 2.2 8.4 1.3 2.6 3 0 0 3 3 3 0 LD-carboxypeptidase N-terminal domain ADP_ribosyl_GH PF03747.14 PVD24337.1 - 4.1e-53 181.0 0.3 4.9e-53 180.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF2989 PF11207.8 PVD24337.1 - 0.00046 20.0 0.8 0.0014 18.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2989) Ninjurin PF04923.12 PVD24338.1 - 6e-21 74.3 4.6 1.1e-20 73.5 4.6 1.4 1 1 0 1 1 1 1 Ninjurin Ni_hydr_CYTB PF01292.20 PVD24338.1 - 0.017 14.7 0.2 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 RD3 PF14473.6 PVD24339.1 - 8.8e-34 116.2 0.2 1.2e-33 115.7 0.2 1.1 1 0 0 1 1 1 1 RD3 protein MLTR_LBD PF17765.1 PVD24339.1 - 0.011 15.8 0.1 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Ifi-6-16 PF06140.13 PVD24340.1 - 9.8e-21 73.5 39.4 5.9e-12 45.3 19.5 2.2 2 0 0 2 2 2 2 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 PVD24341.1 - 2.2e-19 69.1 61.4 2.7e-10 40.0 28.9 2.4 2 0 0 2 2 2 2 Interferon-induced 6-16 family IQ PF00612.27 PVD24341.1 - 6.6e-07 28.6 0.3 1.5e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif NPR3 PF03666.13 PVD24341.1 - 0.00043 19.2 10.2 0.0006 18.7 10.2 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 PVD24341.1 - 0.0007 19.8 3.8 0.00092 19.4 3.8 1.3 1 0 0 1 1 1 1 DDHD domain Pex14_N PF04695.13 PVD24341.1 - 0.00074 20.2 3.7 0.0016 19.1 3.7 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 PVD24341.1 - 0.00085 18.2 12.2 0.0013 17.6 12.2 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2151 PF10221.9 PVD24341.1 - 0.0011 17.7 7.6 0.0014 17.4 7.6 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator MAP7 PF05672.11 PVD24341.1 - 0.0026 17.4 41.3 0.0048 16.6 41.3 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family BUD22 PF09073.10 PVD24341.1 - 0.0028 17.1 23.3 0.0028 17.1 23.3 1.4 2 0 0 2 2 1 1 BUD22 Connexin PF00029.19 PVD24341.1 - 0.0052 16.6 11.9 0.0095 15.7 11.9 1.5 1 0 0 1 1 1 1 Connexin Pkinase_fungal PF17667.1 PVD24341.1 - 0.012 14.4 3.1 0.016 14.0 3.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase RNA_pol_Rpc4 PF05132.14 PVD24341.1 - 0.014 15.8 12.9 0.025 15.0 12.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 PVD24341.1 - 0.046 12.0 21.8 0.015 13.7 18.4 1.8 2 0 0 2 2 2 0 CDC45-like protein RP-C_C PF11800.8 PVD24341.1 - 0.059 13.5 10.1 0.098 12.7 10.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Cellulose_synt PF03552.14 PVD24341.1 - 0.067 11.7 1.4 0.076 11.5 1.4 1.2 1 0 0 1 1 1 0 Cellulose synthase Otopetrin PF03189.13 PVD24341.1 - 0.083 11.7 0.8 0.13 11.0 0.8 1.4 1 0 0 1 1 1 0 Otopetrin Ctr PF04145.15 PVD24341.1 - 0.085 13.5 4.1 0.26 11.9 4.1 1.8 2 0 0 2 2 1 0 Ctr copper transporter family Merozoite_SPAM PF07133.11 PVD24341.1 - 0.14 12.2 37.0 0.2 11.6 37.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RPOL_N PF14700.6 PVD24341.1 - 0.14 11.5 20.5 0.15 11.4 19.0 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Roughex PF06020.11 PVD24341.1 - 0.23 10.5 16.0 0.36 9.9 16.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SAPS PF04499.15 PVD24341.1 - 0.31 9.8 14.3 0.39 9.4 14.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 PVD24341.1 - 0.37 10.0 12.6 0.53 9.5 12.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 PVD24341.1 - 0.43 10.0 23.8 0.89 9.0 23.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF5427 PF10310.9 PVD24341.1 - 0.53 9.2 23.2 0.74 8.7 23.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIP PF07454.11 PVD24341.1 - 0.55 9.7 22.0 0.78 9.1 22.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM91_C PF14648.6 PVD24341.1 - 0.56 9.0 3.4 0.84 8.4 3.4 1.3 1 0 0 1 1 1 0 FAM91 C-terminus NARP1 PF12569.8 PVD24341.1 - 0.61 8.9 24.6 0.88 8.4 24.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nop14 PF04147.12 PVD24341.1 - 0.61 8.2 27.7 0.82 7.8 27.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.6 PVD24341.1 - 0.62 9.6 19.6 0.92 9.1 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 PVD24341.1 - 0.67 9.7 29.5 1.1 9.1 29.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5308 PF17233.2 PVD24341.1 - 0.77 10.0 12.4 0.03 14.5 6.3 1.7 2 0 0 2 2 1 0 Family of unknown function (DUF5308) DUF3807 PF12720.7 PVD24341.1 - 0.9 9.8 27.0 1.7 8.9 27.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CobT PF06213.12 PVD24341.1 - 0.97 8.8 35.1 1.6 8.1 35.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 PVD24341.1 - 1 8.7 25.3 1.4 8.2 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S64 PF08192.11 PVD24341.1 - 1.1 7.7 12.6 1.4 7.3 12.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Gti1_Pac2 PF09729.9 PVD24341.1 - 1.1 9.3 16.5 1.9 8.5 16.5 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2370 PF10176.9 PVD24341.1 - 1.1 8.8 6.5 1.9 8.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Spt20 PF12090.8 PVD24341.1 - 1.2 8.7 21.8 1.7 8.2 21.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF3292 PF11696.8 PVD24341.1 - 1.2 7.4 9.6 1.6 7.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Band_3_cyto PF07565.13 PVD24341.1 - 1.3 8.7 10.2 1.9 8.2 10.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CCDC53 PF10152.9 PVD24341.1 - 1.6 9.1 16.1 2.5 8.5 16.1 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2052 PF09747.9 PVD24341.1 - 2.3 8.3 30.3 3.6 7.7 30.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 PVD24341.1 - 2.4 8.1 13.2 3.8 7.5 13.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PTPRCAP PF15713.5 PVD24341.1 - 2.6 8.3 29.1 4.9 7.4 29.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Slu7 PF11708.8 PVD24341.1 - 2.6 7.7 26.4 4.1 7.1 26.4 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor LMBR1 PF04791.16 PVD24341.1 - 2.8 6.8 3.9 4.6 6.0 3.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF913 PF06025.12 PVD24341.1 - 3.9 6.3 15.5 5.7 5.8 15.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 PVD24341.1 - 4.3 5.3 27.6 6.2 4.8 27.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi GREB1 PF15782.5 PVD24341.1 - 4.5 4.3 11.7 5.9 3.9 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNase_H2_suC PF08615.11 PVD24341.1 - 4.5 7.4 13.4 2.2e+02 2.0 13.3 2.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CAF1 PF04857.20 PVD24341.1 - 4.6 6.3 11.4 6.8 5.8 11.4 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease BORG_CEP PF14957.6 PVD24341.1 - 5 8.3 14.5 9.7 7.4 14.5 1.4 1 0 0 1 1 1 0 Cdc42 effector SLC12 PF03522.15 PVD24341.1 - 5.1 6.0 19.4 6.9 5.6 19.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 eIF3_subunit PF08597.10 PVD24341.1 - 5.3 6.9 34.2 9.5 6.1 34.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Forkhead_N PF08430.12 PVD24341.1 - 5.4 7.6 5.5 1.4 9.6 0.2 2.2 2 0 0 2 2 2 0 Forkhead N-terminal region Afi1 PF07792.12 PVD24341.1 - 6.2 7.3 20.2 11 6.5 20.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PIEZO PF15917.5 PVD24341.1 - 6.4 6.2 24.9 12 5.4 24.9 1.3 1 0 0 1 1 1 0 Piezo FAM60A PF15396.6 PVD24341.1 - 6.9 6.6 17.6 11 5.9 17.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A EOS1 PF12326.8 PVD24341.1 - 6.9 6.6 7.0 15 5.5 7.0 1.6 1 0 0 1 1 1 0 N-glycosylation protein Paf1 PF03985.13 PVD24341.1 - 7.3 5.5 36.8 10 5.0 36.8 1.1 1 0 0 1 1 1 0 Paf1 Spore_coat_CotO PF14153.6 PVD24341.1 - 7.9 6.4 30.1 12 5.8 30.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.10 PVD24341.1 - 8.3 6.7 31.7 14 5.9 31.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hydin_ADK PF17213.3 PVD24341.1 - 8.5 6.6 12.8 17 5.7 12.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SelP_N PF04592.14 PVD24341.1 - 8.6 5.7 15.0 13 5.1 15.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TRAP_alpha PF03896.16 PVD24341.1 - 8.9 5.4 16.0 15 4.7 16.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ATP11 PF06644.11 PVD24341.1 - 9.1 6.0 20.9 13 5.4 20.9 1.2 1 0 0 1 1 1 0 ATP11 protein Pkinase PF00069.25 PVD24343.1 - 1.8e-08 34.1 0.0 1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24343.1 - 5.8e-07 29.1 0.0 1.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase 4PPT_N PF17837.1 PVD24343.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Ras PF00071.22 PVD24344.1 - 5.5e-59 198.4 0.3 6.7e-59 198.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24344.1 - 3.1e-21 75.8 0.0 5.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24344.1 - 4.5e-09 36.0 0.1 5.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD24344.1 - 6.1e-05 22.7 0.4 0.00012 21.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD24344.1 - 0.00049 20.2 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24344.1 - 0.00092 19.2 2.7 0.2 11.6 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 PVD24344.1 - 0.012 14.8 0.8 1.8 7.7 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ParA PF10609.9 PVD24344.1 - 0.11 11.9 0.2 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase DUF2955 PF11168.8 PVD24345.1 - 0.066 13.1 0.4 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) SNF2_N PF00176.23 PVD24346.1 - 2e-49 168.2 0.1 5.5e-49 166.8 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD24346.1 - 2.6e-15 56.7 0.0 7e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD24346.1 - 1.4e-07 31.7 0.0 1.4e-07 31.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PVD24346.1 - 0.0003 20.1 0.0 0.009 15.3 0.0 2.7 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 PVD24347.1 - 3.8e-15 56.0 7.3 1.3e-05 25.8 0.0 8.2 7 1 1 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD24347.1 - 4.8e-15 55.6 1.1 0.0005 20.3 0.0 6.1 2 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD24347.1 - 1.5e-05 24.9 0.6 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC3 PF12895.7 PVD24347.1 - 0.00034 20.8 7.8 0.25 11.6 0.4 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 WD40_like PF17005.5 PVD24347.1 - 0.00059 19.2 1.8 2.4 7.4 0.0 3.7 3 1 1 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 PVD24347.1 - 0.00083 18.5 1.3 0.37 9.8 0.0 4.4 3 3 1 4 4 4 1 Coatomer WD associated region Clathrin PF00637.20 PVD24347.1 - 0.00098 19.0 2.7 13 5.6 0.2 4.5 2 1 2 4 4 4 0 Region in Clathrin and VPS TPR_7 PF13176.6 PVD24347.1 - 0.0012 18.8 2.7 0.022 14.8 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PHTB1_N PF14727.6 PVD24347.1 - 0.0025 17.2 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 PTHB1 N-terminus TPR_14 PF13428.6 PVD24347.1 - 0.024 15.4 0.8 8.7 7.5 0.0 4.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD24347.1 - 0.034 14.2 18.0 0.038 14.1 0.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD24347.1 - 0.099 12.9 8.5 0.19 12.0 0.2 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD24347.1 - 0.1 12.0 1.7 7.5 5.8 0.0 3.2 3 0 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 PVD24347.1 - 0.16 11.9 2.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S51 PF03575.17 PVD24347.1 - 0.19 11.4 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S51 TPR_19 PF14559.6 PVD24347.1 - 0.35 11.4 2.3 26 5.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD24347.1 - 0.71 9.8 9.2 0.24 11.3 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD24347.1 - 2.2 8.7 8.1 0.47 10.8 0.4 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.11 PVD24348.1 - 6.4e-18 64.6 30.1 6.4e-18 64.6 30.1 3.5 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 PVD24348.1 - 1.8e-16 60.2 1.2 2.7e-14 53.2 0.0 3.1 3 1 1 4 4 4 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD24348.1 - 3.6e-14 52.6 0.1 5e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD24348.1 - 0.00023 21.1 0.6 0.18 11.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD24348.1 - 0.053 13.1 5.4 0.061 12.9 0.0 3.2 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain cobW PF02492.19 PVD24348.1 - 0.053 13.1 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2894 PF11445.8 PVD24348.1 - 3.2 8.2 11.2 0.68 10.4 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Dynamin_N PF00350.23 PVD24348.1 - 9 6.3 21.5 0.057 13.5 0.8 3.9 3 2 0 3 3 3 0 Dynamin family Bromodomain PF00439.25 PVD24349.1 - 3.8e-98 321.7 27.1 1.8e-21 76.0 0.3 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 PVD24349.1 - 5.6e-42 142.4 0.8 1.2e-20 73.5 0.2 2.5 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 PVD24349.1 - 3.1e-14 53.1 1.6 6.7e-14 52.1 0.2 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD24349.1 - 1.5e-10 41.5 1.4 1.5e-10 41.5 1.4 3.0 3 0 0 3 3 3 1 HMG-box domain DUF1640 PF07798.11 PVD24349.1 - 0.03 14.4 0.4 0.081 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DALR_1 PF05746.15 PVD24350.1 - 9.3e-17 61.3 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain GST_N_2 PF13409.6 PVD24351.1 - 3e-09 37.0 0.0 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PVD24351.1 - 3.3e-09 37.0 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD24351.1 - 5e-06 26.8 0.1 1.2e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD24351.1 - 7.3e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PVD24351.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pkinase PF00069.25 PVD24352.1 - 4.9e-76 255.6 0.0 7.3e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24352.1 - 2.4e-35 122.1 0.0 4e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD24352.1 - 4.8e-06 26.1 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD24352.1 - 1e-05 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PVD24352.1 - 0.00069 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PVD24352.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD24352.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase GST_C_5 PF16865.5 PVD24352.1 - 0.11 13.1 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tyrosinase PF00264.20 PVD24352.1 - 0.14 12.4 1.0 0.21 11.8 1.0 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase Tetraspanin PF00335.20 PVD24353.1 - 0.07 12.8 1.9 0.12 12.1 1.9 1.4 1 0 0 1 1 1 0 Tetraspanin family TMEM154 PF15102.6 PVD24355.1 - 0.0024 17.8 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF4013 PF13197.6 PVD24355.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Epiglycanin_C PF14654.6 PVD24355.1 - 0.017 15.2 0.6 0.039 14.0 0.1 1.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region PRIMA1 PF16101.5 PVD24355.1 - 0.048 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Comm PF15957.5 PVD24355.1 - 0.19 12.1 2.4 4.7 7.6 0.2 2.6 2 1 1 3 3 3 0 Commissureless ubiquitin PF00240.23 PVD24356.1 - 5.5e-08 32.5 0.0 8.1e-07 28.7 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PVD24356.1 - 1.2e-05 25.0 0.3 9.6e-05 22.1 0.0 2.7 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DUF4041 PF13250.6 PVD24356.1 - 0.069 13.0 0.3 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) zf_UBZ PF18439.1 PVD24356.1 - 0.088 12.4 0.1 0.32 10.6 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger MOSC PF03473.17 PVD24356.1 - 0.093 12.8 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 MOSC domain RNA_POL_M_15KD PF02150.16 PVD24356.1 - 0.095 12.6 0.8 0.23 11.4 0.8 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Ribosomal_L27e PF01777.18 PVD24356.1 - 0.81 10.1 6.5 0.35 11.2 2.5 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family IQ PF00612.27 PVD24356.1 - 9.4 6.3 7.5 0.26 11.2 0.2 2.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif ubiquitin PF00240.23 PVD24357.1 - 1.2e-08 34.6 0.0 2.8e-07 30.2 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PVD24357.1 - 1.1e-05 25.1 0.0 3.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Dynein_C PF18199.1 PVD24358.1 - 4.6e-116 387.4 0.0 2e-115 385.3 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 PVD24358.1 - 3.2e-114 382.1 18.3 3.2e-114 382.1 18.3 4.7 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PVD24358.1 - 1.7e-109 365.8 0.2 9.1e-82 274.6 0.0 3.9 3 1 1 4 4 4 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 PVD24358.1 - 7.4e-83 277.8 5.3 6.6e-70 235.4 0.0 3.3 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD24358.1 - 9.1e-83 276.2 0.2 6.9e-81 270.1 0.1 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_9 PF12781.7 PVD24358.1 - 4.3e-79 264.7 1.6 4.3e-79 264.7 1.6 3.2 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PVD24358.1 - 8.4e-66 220.8 0.0 4.6e-65 218.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD24358.1 - 6.1e-48 161.8 0.0 7.5e-46 155.1 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD24358.1 - 7.3e-48 163.3 9.2 7.3e-48 163.3 9.2 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PVD24358.1 - 1.9e-37 128.3 1.3 6.1e-36 123.4 0.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD24358.1 - 1.5e-18 66.8 0.9 2.3e-17 63.1 0.4 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PVD24358.1 - 1e-12 48.2 0.0 1.5e-07 31.5 0.0 4.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD24358.1 - 6.6e-06 26.6 0.1 0.23 11.9 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD24358.1 - 0.00024 21.4 3.1 5 7.4 0.0 5.2 5 0 0 5 5 4 1 AAA domain DUF4349 PF14257.6 PVD24358.1 - 0.0052 16.3 8.8 0.083 12.3 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4349) DUF1908 PF08926.11 PVD24358.1 - 0.0097 15.0 0.9 0.026 13.6 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) RNA_helicase PF00910.22 PVD24358.1 - 0.01 16.2 0.0 13 6.2 0.0 3.4 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PVD24358.1 - 0.013 15.9 0.7 9.2 6.6 0.0 4.0 4 0 0 4 4 3 0 AAA ATPase domain AAA_18 PF13238.6 PVD24358.1 - 0.041 14.4 0.1 0.59 10.7 0.0 3.2 2 0 0 2 2 1 0 AAA domain Baculo_PEP_C PF04513.12 PVD24358.1 - 0.44 10.6 10.8 5.2 7.1 0.1 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MDMPI_N PF11716.8 PVD24358.1 - 0.75 10.5 5.1 6.3 7.5 2.9 2.6 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Clr5 PF14420.6 PVD24358.1 - 1.8 8.8 7.8 1.1 9.5 0.5 3.9 3 0 0 3 3 3 0 Clr5 domain 7tm_1 PF00001.21 PVD24359.1 - 4.5e-35 121.2 7.1 4.5e-35 121.2 7.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD24359.1 - 0.0014 18.3 5.7 0.0035 17.0 4.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx NDUFA12 PF05071.16 PVD24360.1 - 1.7e-31 108.9 2.7 2e-31 108.7 2.7 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 AChE_tetra PF08674.10 PVD24360.1 - 1.3 8.8 4.3 0.56 10.0 0.9 2.0 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Ank_2 PF12796.7 PVD24361.1 - 2.1e-24 85.9 0.0 5.3e-15 55.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD24361.1 - 2.1e-19 69.6 0.3 3.3e-07 30.7 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD24361.1 - 8.4e-19 67.1 0.0 0.00026 21.3 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 PVD24361.1 - 4.1e-17 60.5 0.0 0.0018 18.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PVD24361.1 - 6.6e-16 58.2 0.1 3.6e-08 33.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 PVD24361.1 - 1.4e-09 38.3 0.1 2.3e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD24361.1 - 9.3e-08 32.1 0.1 1.8e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) wnt PF00110.19 PVD24362.1 - 1.4e-122 409.1 21.7 1.9e-122 408.7 21.7 1.2 1 0 0 1 1 1 1 wnt family HSP70 PF00012.20 PVD24364.1 - 1.7e-112 376.6 1.4 1.9e-112 376.4 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD24364.1 - 3.2e-10 39.4 0.6 1.9e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 PVD24364.1 - 0.0082 15.9 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PBP1_TM PF14812.6 PVD24365.1 - 0.00022 21.5 0.2 0.00046 20.5 0.2 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal NEMP PF10225.9 PVD24365.1 - 4.5 6.9 6.5 5.2 6.7 0.7 2.0 1 1 1 2 2 2 0 NEMP family TMEM52 PF14979.6 PVD24365.1 - 6.8 6.6 10.2 14 5.6 10.2 1.5 1 0 0 1 1 1 0 Transmembrane 52 DnaJ PF00226.31 PVD24366.1 - 1.5e-27 95.5 8.6 2.9e-27 94.6 8.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4446 PF14584.6 PVD24366.1 - 0.08 12.9 0.1 0.08 12.9 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SET PF00856.28 PVD24367.1 - 4.8e-22 79.1 0.1 4.8e-22 79.1 0.1 2.6 3 2 0 3 3 3 1 SET domain Pre-SET PF05033.16 PVD24367.1 - 7.2e-18 65.2 7.9 7.2e-18 65.2 7.9 2.9 3 1 0 3 3 3 1 Pre-SET motif Herpes_DNAp_acc PF04929.12 PVD24367.1 - 2.6 6.9 5.4 4.7 6.1 5.4 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HMG_box PF00505.19 PVD24369.1 - 1.3e-16 60.8 3.5 3.1e-16 59.5 3.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD24369.1 - 5e-09 36.6 4.3 1.4e-08 35.2 4.3 1.8 1 0 0 1 1 1 1 HMG-box domain zf-C2H2_4 PF13894.6 PVD24369.1 - 2.5e-06 27.9 7.0 0.026 15.4 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD24369.1 - 0.00034 20.9 7.7 0.064 13.7 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD24369.1 - 0.024 15.0 0.7 0.024 15.0 0.7 2.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_aberr PF17017.5 PVD24369.1 - 0.026 14.7 1.0 0.87 9.7 0.1 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 PVD24369.1 - 0.029 14.7 0.6 0.082 13.2 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon IBR PF01485.21 PVD24369.1 - 0.029 14.6 2.5 0.029 14.6 2.5 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain AAA_12 PF13087.6 PVD24370.1 - 3e-47 160.9 0.0 6.8e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD24370.1 - 7.7e-30 104.5 3.3 3.2e-14 53.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 PVD24370.1 - 5.9e-13 49.4 0.0 2e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD24370.1 - 1.2e-11 44.7 0.0 2.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 PVD24370.1 - 9e-07 28.7 0.0 0.00055 19.6 0.0 3.0 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PVD24370.1 - 6.3e-06 25.8 0.0 0.00069 19.1 0.0 2.4 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 PVD24370.1 - 7.4e-06 26.1 0.0 4.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 PVD24370.1 - 2.5e-05 24.4 2.2 2.5e-05 24.4 2.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PVD24370.1 - 4e-05 23.9 2.5 0.00012 22.3 2.0 2.1 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.6 PVD24370.1 - 0.0003 21.1 0.0 0.00091 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-met PF12874.7 PVD24370.1 - 0.00047 20.4 2.2 0.00058 20.2 0.8 2.0 2 0 0 2 2 1 1 Zinc-finger of C2H2 type Helicase_RecD PF05127.14 PVD24370.1 - 0.0024 17.7 0.6 0.041 13.7 0.0 2.7 3 0 0 3 3 3 1 Helicase zf-C2H2 PF00096.26 PVD24370.1 - 0.0031 17.9 0.7 0.0088 16.4 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type PIF1 PF05970.14 PVD24370.1 - 0.0066 15.7 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase Viral_helicase1 PF01443.18 PVD24370.1 - 0.022 14.5 0.0 6 6.5 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 PVD24370.1 - 0.024 15.1 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_11 PF16622.5 PVD24370.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PVD24370.1 - 0.054 14.4 0.2 0.16 12.9 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PhoH PF02562.16 PVD24370.1 - 0.057 12.9 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 PVD24370.1 - 0.064 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_6 PF13912.6 PVD24370.1 - 0.19 11.8 2.9 0.23 11.5 1.6 1.8 2 0 0 2 2 1 0 C2H2-type zinc finger Ldl_recept_a PF00057.18 PVD24371.1 - 3.7e-14 52.6 14.7 8.3e-14 51.5 14.7 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD24372.1 - 5e-46 154.6 74.1 4.5e-14 52.4 8.4 4.3 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A C1q PF00386.21 PVD24373.1 - 4.6e-20 72.1 0.3 2.2e-19 69.9 0.1 1.9 2 0 0 2 2 2 1 C1q domain Baculo_PEP_C PF04513.12 PVD24373.1 - 0.12 12.5 1.3 0.4 10.7 1.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ldl_recept_a PF00057.18 PVD24374.1 - 5.4e-34 116.1 47.8 3.8e-13 49.4 10.6 3.4 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD24375.1 - 1.3e-33 114.9 53.6 1.4e-12 47.6 8.0 3.9 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Pkinase PF00069.25 PVD24376.1 - 1.2e-60 205.1 0.0 1.6e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24376.1 - 4e-39 134.5 0.0 5.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD24376.1 - 0.0022 18.0 0.0 0.57 10.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD24376.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PVD24376.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 PVD24377.1 - 2.3e-53 181.3 0.0 2.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24377.1 - 1.3e-36 126.2 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD24377.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD24377.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PVD24377.1 - 0.11 12.4 0.0 0.86 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Usp PF00582.26 PVD24379.1 - 6.1e-13 49.5 0.0 9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Sulfate_transp PF00916.20 PVD24380.1 - 5.1e-85 285.5 9.3 6.7e-85 285.1 9.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD24380.1 - 9.1e-25 86.6 0.0 1.6e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD24380.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 STAS domain DUF5493 PF17597.2 PVD24380.1 - 0.1 12.9 2.8 0.13 12.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Ribosomal_L10 PF00466.20 PVD24381.1 - 0.0023 18.1 0.1 0.0028 17.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L10 Sulfate_transp PF00916.20 PVD24381.1 - 0.25 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Sulfate permease family Pkinase PF00069.25 PVD24382.1 - 4.8e-25 88.4 0.0 8.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24382.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ran_BP1 PF00638.18 PVD24383.1 - 1.7e-135 444.8 15.9 9e-45 151.9 2.7 4.8 4 0 0 4 4 4 4 RanBP1 domain zf-RanBP PF00641.18 PVD24383.1 - 1.2e-06 27.7 2.1 1.2e-06 27.7 2.1 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others IR1-M PF12185.8 PVD24383.1 - 2e-06 27.6 0.0 6.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Nup358/RanBP2 E3 ligase domain YlbD_coat PF14071.6 PVD24383.1 - 0.21 11.9 3.4 0.73 10.1 3.4 1.9 1 0 0 1 1 1 0 Putative coat protein DUF948 PF06103.11 PVD24383.1 - 0.58 10.4 3.8 2.6 8.4 3.8 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Med28 PF11594.8 PVD24383.1 - 4.4 7.4 8.5 0.69 10.0 3.9 2.1 2 0 0 2 2 2 0 Mediator complex subunit 28 Abhydrolase_1 PF00561.20 PVD24384.1 - 8.2e-19 68.2 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD24384.1 - 3.8e-13 50.6 0.0 5.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD24384.1 - 3.7e-09 36.2 0.2 8e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Viral_alk_exo PF01771.17 PVD24384.1 - 1.2e-06 27.6 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Viral alkaline exonuclease YqaJ PF09588.10 PVD24384.1 - 0.00025 21.2 0.3 0.00067 19.8 0.1 1.8 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain Peptidase_S28 PF05577.12 PVD24384.1 - 0.012 14.4 0.0 0.07 11.9 0.0 1.9 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Lipase PF00151.19 PVD24384.1 - 0.086 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase Y_phosphatase PF00102.27 PVD24385.1 - 2.1e-103 345.0 0.0 1.1e-73 247.6 0.0 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PVD24385.1 - 0.00051 20.2 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD24385.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PVD24385.1 - 0.007 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Adeno_E3_CR2 PF02439.15 PVD24385.1 - 0.022 14.5 1.0 0.04 13.7 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PVD24385.1 - 0.037 14.9 0.1 0.095 13.6 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD24385.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) F5_F8_type_C PF00754.25 PVD24385.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 F5/8 type C domain Stevor PF17410.2 PVD24385.1 - 0.087 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 PVD24385.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 PVD24385.1 - 0.87 9.7 6.9 1.9 8.6 6.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Baculo_11_kDa PF06143.11 PVD24385.1 - 1.1 8.9 3.1 2.4 7.8 3.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Exo_endo_phos_2 PF14529.6 PVD24386.1 - 0.055 13.3 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Y_phosphatase PF00102.27 PVD24387.1 - 2.8e-86 288.9 1.4 1.2e-76 257.4 0.4 3.3 2 1 1 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PVD24387.1 - 0.00087 19.4 0.0 0.0032 17.6 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 PVD24387.1 - 0.0093 15.8 0.0 0.047 13.5 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD24387.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 PVD24388.1 - 6.1e-48 163.4 0.2 1.9e-29 102.9 0.0 3.5 2 1 1 3 3 3 3 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 PVD24388.1 - 8.7e-05 22.6 1.8 9.9e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 F5/8 type C domain Y_phosphatase3 PF13350.6 PVD24388.1 - 0.0032 17.5 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Mucin PF01456.17 PVD24388.1 - 0.034 14.1 21.5 0.087 12.8 21.5 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein EphA2_TM PF14575.6 PVD24388.1 - 0.11 13.4 0.2 0.27 12.1 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cytadhesin_P30 PF07271.11 PVD24388.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 RIFIN PF02009.16 PVD24388.1 - 0.18 11.7 0.6 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 Rifin ABC2_membrane PF01061.24 PVD24389.1 - 4.4e-39 134.1 13.7 8.5e-39 133.1 13.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD24389.1 - 1.2e-20 74.4 0.0 2.5e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PVD24389.1 - 1.9e-05 23.9 8.2 1.9e-05 23.9 8.2 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PVD24389.1 - 0.0009 19.2 0.1 0.0022 17.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PVD24389.1 - 0.0042 17.4 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PVD24389.1 - 0.024 14.4 0.2 0.056 13.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PVD24389.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 PVD24389.1 - 0.027 14.6 0.1 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Septin PF00735.18 PVD24389.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 PVD24389.1 - 0.035 14.7 0.2 0.08 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 PVD24389.1 - 0.042 14.1 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD24389.1 - 0.042 14.2 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 PVD24389.1 - 0.042 13.4 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD24389.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PVD24389.1 - 0.15 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase LELP1 PF15042.6 PVD24390.1 - 0.46 10.9 12.7 0.15 12.5 4.1 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 SelP_N PF04592.14 PVD24390.1 - 1.6 8.1 17.3 2.5 7.5 17.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.16 PVD24390.1 - 6.2 6.1 8.6 7.6 5.8 8.6 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein zf-HC5HC2H_2 PF13832.6 PVD24392.1 - 1.7e-36 124.7 5.2 1.7e-36 124.7 5.2 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 PVD24392.1 - 7e-32 111.0 7.1 7e-32 111.0 7.1 3.4 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 PVD24392.1 - 7.4e-25 87.0 1.8 7.4e-25 87.0 1.8 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 PVD24392.1 - 3.6e-24 84.7 0.3 9.7e-24 83.3 0.3 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 PVD24392.1 - 7e-19 68.0 0.1 3.1e-18 66.0 0.1 2.2 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 PVD24392.1 - 1.1e-14 53.6 3.2 1.1e-14 53.6 3.2 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PVD24392.1 - 1.4e-08 34.4 23.9 1.9e-07 30.9 9.0 2.7 2 0 0 2 2 2 2 PHD-finger zf-C2H2_aberr PF17017.5 PVD24392.1 - 0.03 14.5 0.4 0.066 13.4 0.4 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger Ins_allergen_rp PF06757.13 PVD24392.1 - 0.034 14.1 0.3 0.09 12.7 0.3 1.7 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification C1_1 PF00130.22 PVD24392.1 - 2.7 7.9 17.1 0.056 13.3 2.6 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TSP_1 PF00090.19 PVD24393.1 - 7.3e-36 122.2 137.4 7.5e-09 35.7 8.2 12.2 10 2 1 11 11 11 8 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 PVD24393.1 - 2.1e-28 98.6 0.1 4.3e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 PVD24393.1 - 1.5e-22 80.4 0.2 5.8e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 PVD24393.1 - 1.7e-20 73.8 0.1 1.7e-20 73.8 0.1 2.4 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 PVD24393.1 - 3.3e-19 69.2 18.4 1.5e-18 67.0 10.7 7.4 6 2 1 8 8 8 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 PVD24393.1 - 3.3e-13 50.2 0.3 8.3e-13 48.9 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD24393.1 - 7.4e-09 35.8 0.6 1.6e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD24393.1 - 1.2e-08 35.5 0.0 2.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD24393.1 - 0.00013 21.6 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like GON PF08685.11 PVD24394.1 - 5.2e-57 193.0 0.6 3.1e-31 108.8 0.2 2.5 2 0 0 2 2 2 2 GON domain TSP_1 PF00090.19 PVD24394.1 - 8.9e-23 80.3 61.8 3.1e-08 33.7 5.5 5.8 6 0 0 6 6 6 4 Thrombospondin type 1 domain zf-H2C2_2 PF13465.6 PVD24395.1 - 0.0028 18.0 0.7 0.0081 16.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD24395.1 - 3 8.9 8.0 14 6.8 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Ank PF00023.30 PVD24399.1 - 2.2e-12 46.8 2.0 4e-06 27.0 0.1 3.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 PVD24399.1 - 4.7e-11 43.1 0.2 1.9e-08 34.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD24399.1 - 3.8e-09 36.0 0.1 0.00034 20.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PVD24399.1 - 2.4e-08 34.4 0.1 0.0015 19.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD24399.1 - 4.5e-06 26.8 0.2 0.0077 16.5 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-C2H2_6 PF13912.6 PVD24402.1 - 0.027 14.5 0.0 0.085 12.9 0.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD24402.1 - 0.14 12.6 2.0 17 6.1 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD24402.1 - 1.7 9.7 11.1 0.29 12.1 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Ribophorin_I PF04597.14 PVD24403.1 - 4.1e-143 477.7 6.1 5.6e-143 477.3 6.1 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 PVD24403.1 - 6.2e-06 26.8 2.4 1.5e-05 25.5 2.4 1.7 1 0 0 1 1 1 1 DNA repair REX1-B Rab5-bind PF09311.11 PVD24403.1 - 0.00034 20.1 4.4 0.00058 19.4 4.4 1.3 1 0 0 1 1 1 1 Rabaptin-like protein DUF4407 PF14362.6 PVD24403.1 - 0.0031 16.9 2.7 0.0048 16.3 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Requiem_N PF14051.6 PVD24403.1 - 0.0054 16.9 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. DUF2481 PF10654.9 PVD24403.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Phage_GP20 PF06810.11 PVD24403.1 - 0.1 12.4 2.5 0.19 11.5 2.5 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Syntaxin_2 PF14523.6 PVD24403.1 - 0.43 11.0 4.2 0.74 10.2 3.1 1.9 1 1 1 2 2 2 0 Syntaxin-like protein UPF0449 PF15136.6 PVD24403.1 - 4.3 7.9 5.6 2.7 8.5 3.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF737 PF05300.11 PVD24403.1 - 6.3 7.1 8.0 27 5.0 8.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF737) IBN_N PF03810.19 PVD24404.1 - 2.9e-11 43.1 0.0 9.1e-11 41.5 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PVD24404.1 - 9.3e-09 35.5 0.6 1.5e-06 28.4 0.0 4.2 5 0 0 5 5 5 1 Exportin 1-like protein Cse1 PF08506.10 PVD24404.1 - 6.7e-06 25.2 0.0 0.00017 20.6 0.2 2.5 3 0 0 3 3 3 1 Cse1 HEAT_EZ PF13513.6 PVD24404.1 - 0.00099 19.6 0.1 10 6.8 0.0 5.1 4 0 0 4 4 4 1 HEAT-like repeat RIX1 PF08167.12 PVD24404.1 - 0.0018 18.0 2.8 0.83 9.4 0.0 3.8 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis Na_trans_assoc PF06512.13 PVD24404.1 - 0.062 13.6 2.3 0.13 12.5 2.3 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Mu-like_Pro PF10123.9 PVD24404.1 - 0.13 11.8 0.1 0.59 9.6 0.1 1.9 2 0 0 2 2 2 0 Mu-like prophage I protein DUF3385 PF11865.8 PVD24404.1 - 0.14 12.1 4.0 13 5.6 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) DNA_pol_phi PF04931.13 PVD24404.1 - 0.2 9.7 9.7 0.43 8.6 9.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 PVD24404.1 - 0.51 9.4 7.5 0.81 8.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 PVD24404.1 - 7.2 5.8 6.8 11 5.2 6.8 1.1 1 0 0 1 1 1 0 BUD22 Bromo_TP PF07524.13 PVD24405.1 - 3.4e-20 71.8 0.0 5.9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 PVD24405.1 - 2.6e-11 43.2 9.7 6.6e-11 41.9 9.7 1.7 1 0 0 1 1 1 1 PHD-finger Bromo_TP_like PF17027.5 PVD24405.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Histone-fold protein PHD_2 PF13831.6 PVD24405.1 - 0.27 10.8 9.1 0.043 13.4 4.4 2.0 2 0 0 2 2 2 0 PHD-finger LicD PF04991.13 PVD24405.1 - 6.8 6.8 14.1 0.36 10.9 4.7 2.9 3 0 0 3 3 3 0 LicD family Arf PF00025.21 PVD24406.1 - 1.8e-53 180.6 0.0 2.2e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PVD24406.1 - 2.8e-12 46.9 0.0 4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD24406.1 - 4.1e-12 46.0 0.0 4.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PVD24406.1 - 1e-11 44.7 0.4 8.8e-06 25.1 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PVD24406.1 - 5.8e-08 32.4 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD24406.1 - 1.4e-07 31.5 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD24406.1 - 2.3e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD24406.1 - 0.00018 21.1 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 PVD24406.1 - 0.00048 19.6 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 PVD24406.1 - 0.014 15.7 0.0 0.048 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PVD24406.1 - 0.038 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD24406.1 - 0.041 13.8 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 PVD24406.1 - 0.06 13.7 0.0 0.81 10.0 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Septin PF00735.18 PVD24406.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 PVD24406.1 - 0.11 12.6 0.0 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 Dynamin family Rsa3 PF14615.6 PVD24406.1 - 0.11 12.0 0.7 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 Ribosome-assembly protein 3 FtsK_SpoIIIE PF01580.18 PVD24406.1 - 0.2 11.0 0.1 0.42 9.9 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.32 PVD24408.1 - 6.6e-45 150.2 34.1 8e-07 29.7 0.4 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 PVD24408.1 - 1.2e-11 44.3 2.6 2.7e-11 43.2 2.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD24408.1 - 5.8e-09 35.6 0.3 3e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 F-box domain Nup160 PF11715.8 PVD24408.1 - 6.5e-08 31.7 18.8 0.12 10.9 0.2 5.5 2 2 3 5 5 5 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 PVD24408.1 - 0.00041 20.2 0.4 0.0014 18.5 0.4 2.0 1 0 0 1 1 1 1 F-box EpCAM_N PF18635.1 PVD24408.1 - 0.00065 19.8 2.6 0.31 11.2 0.0 3.5 3 0 0 3 3 3 2 Epithelial cell adhesion molecule N-terminal domain WD40_like PF17005.5 PVD24408.1 - 0.0014 18.0 0.3 0.0067 15.8 0.3 2.1 1 1 0 1 1 1 1 WD40-like domain Mcl1_mid PF12341.8 PVD24408.1 - 0.0088 15.4 2.0 1.1 8.5 0.2 2.9 1 1 2 3 3 3 2 Minichromosome loss protein, Mcl1, middle region HARP PF07443.13 PVD24408.1 - 0.26 11.0 1.0 43 3.8 0.0 3.7 4 0 0 4 4 4 0 HepA-related protein (HARP) LAMTOR5 PF16672.5 PVD24409.1 - 1.9e-21 75.8 0.2 2e-21 75.7 0.2 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 PVD24409.1 - 0.015 15.0 0.1 0.031 14.1 0.1 1.6 1 1 0 1 1 1 0 Roadblock/LC7 domain 2-Hacid_dh_C PF02826.19 PVD24410.1 - 2.9e-23 82.2 0.0 1.1e-11 44.5 0.0 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PVD24410.1 - 0.0064 16.7 0.1 0.014 15.6 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PVD24410.1 - 0.07 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain N6-adenineMlase PF10237.9 PVD24410.1 - 0.08 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase F420_oxidored PF03807.17 PVD24410.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 PVD24410.1 - 0.15 12.4 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LisH PF08513.11 PVD24411.1 - 3.3e-05 23.7 1.0 0.00029 20.7 0.1 2.7 2 0 0 2 2 2 1 LisH ANAPC4_WD40 PF12894.7 PVD24411.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4_WD40 PF12894.7 PVD24412.1 - 0.0081 16.4 0.0 0.42 10.9 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD24412.1 - 0.049 14.5 0.2 7.6 7.6 0.1 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat eIF2A PF08662.11 PVD24412.1 - 0.094 12.6 0.1 7 6.5 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TTL PF03133.15 PVD24413.1 - 9.3e-73 244.9 1.4 9.3e-73 244.9 1.4 3.0 3 1 1 4 4 4 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD24413.1 - 9.9e-05 21.7 0.2 0.0086 15.3 0.0 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD24413.1 - 0.061 12.6 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp VirB7 PF17413.2 PVD24414.1 - 0.047 13.0 0.4 0.086 12.2 0.4 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 XRN_N PF03159.18 PVD24414.1 - 0.64 9.4 4.2 1.8 8.0 0.0 2.6 2 1 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus CN_hydrolase PF00795.22 PVD24417.1 - 2.3e-65 220.6 0.2 3e-65 220.2 0.2 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 PVD24417.1 - 5.4e-22 78.4 0.2 1.3e-21 77.2 0.2 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PVD24417.1 - 1.8e-05 25.2 0.1 3.6e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MTHFR PF02219.17 PVD24417.1 - 0.088 12.1 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase Kin17_mid PF10357.9 PVD24418.1 - 1.4e-49 167.2 1.8 1.4e-49 167.2 1.8 2.6 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PVD24418.1 - 1.3e-18 66.9 2.9 1.3e-18 66.9 2.9 2.2 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 PVD24418.1 - 0.00055 19.8 1.1 0.0074 16.2 0.1 2.8 2 0 0 2 2 2 1 KOW motif zf-met PF12874.7 PVD24418.1 - 0.0024 18.2 6.4 0.006 16.9 6.4 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD24418.1 - 0.0067 16.7 0.8 0.0067 16.7 0.8 2.8 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PVD24418.1 - 0.15 12.4 8.9 0.058 13.7 5.7 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Iso_dh PF00180.20 PVD24419.1 - 3.3e-28 98.8 0.0 4.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Transket_pyr PF02779.24 PVD24420.1 - 1e-45 155.6 0.0 1.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PVD24420.1 - 3.9e-41 139.8 0.1 7.5e-41 138.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ank_3 PF13606.6 PVD24420.1 - 8.3e-06 25.8 0.3 0.1 13.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PVD24420.1 - 2.7e-05 24.6 0.5 7.8e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD24420.1 - 0.00096 19.7 0.6 0.075 13.6 0.4 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD24420.1 - 0.0011 19.3 0.8 0.21 12.1 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PVD24420.1 - 0.071 13.4 1.0 6.5 7.2 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) PFOR_II PF17147.4 PVD24420.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II MSC PF09402.10 PVD24421.1 - 1.8e-27 96.7 2.5 2.9e-27 96.0 2.5 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RBM39linker PF15519.6 PVD24421.1 - 2e-05 25.6 0.9 0.0002 22.3 0.1 2.6 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein LEM PF03020.15 PVD24421.1 - 0.0035 16.9 0.9 0.011 15.2 0.2 2.2 2 1 0 2 2 2 1 LEM domain Ni_hydr_CYTB PF01292.20 PVD24421.1 - 0.034 13.7 0.3 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 PepSY_TM PF03929.16 PVD24421.1 - 0.038 13.7 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM region UPF0242 PF06785.11 PVD24421.1 - 0.059 13.5 0.2 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Chordopox_L2 PF05803.12 PVD24421.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.3 3 0 0 3 3 3 0 Chordopoxvirus L2 protein AAA_30 PF13604.6 PVD24422.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD24422.1 - 4.2e-05 24.0 0.0 7.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain GvpD PF07088.11 PVD24422.1 - 7.4e-05 21.6 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_19 PF13245.6 PVD24422.1 - 0.00016 22.0 0.0 0.00041 20.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PVD24422.1 - 0.00025 20.6 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 PVD24422.1 - 0.0004 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD24422.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 PVD24422.1 - 0.026 14.1 0.0 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PVD24422.1 - 0.041 13.7 0.3 0.086 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD24422.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 PVD24422.1 - 0.047 14.1 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 PVD24422.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gelsolin PF00626.22 PVD24423.1 - 4.1e-25 87.5 0.2 2.7e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Gelsolin repeat PV_NSP1 PF12433.8 PVD24423.1 - 0.12 12.7 1.2 0.95 9.8 0.1 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein 1 baeRF_family3 PF18845.1 PVD24423.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Gelsolin PF00626.22 PVD24424.1 - 2.3e-41 139.6 0.0 4.5e-15 55.3 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat Gelsolin PF00626.22 PVD24425.1 - 1.3e-43 146.7 0.1 1.5e-15 56.8 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat Copine PF07002.16 PVD24426.1 - 2.9e-80 268.8 0.3 8.9e-80 267.2 0.1 1.9 2 0 0 2 2 2 1 Copine PARP PF00644.20 PVD24426.1 - 6.6e-33 113.9 0.0 1.6e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PVD24426.1 - 3.2e-32 111.5 0.6 7e-32 110.4 0.6 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain vWA-TerF-like PF10138.9 PVD24426.1 - 1.6e-06 28.3 0.0 1.4e-05 25.3 0.0 2.2 2 1 0 2 2 2 1 vWA found in TerF C terminus PDEase_I PF00233.19 PVD24426.1 - 0.3 10.8 1.4 1.4 8.6 1.4 1.9 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase PARP PF00644.20 PVD24427.1 - 4.5e-47 160.2 0.0 9.2e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PVD24427.1 - 1.5e-43 148.1 0.5 3e-43 147.2 0.5 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PVD24427.1 - 1.2e-27 95.8 2.8 1.2e-27 95.8 2.8 2.2 2 0 0 2 2 2 1 WGR domain PAX PF00292.18 PVD24429.1 - 2.6e-62 208.3 0.7 4e-62 207.7 0.7 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 PVD24429.1 - 3.2e-05 24.5 0.4 0.01 16.5 0.0 2.5 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 PVD24429.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Cast PF10174.9 PVD24430.1 - 5.5e-118 395.3 139.3 1.2e-115 387.5 139.3 2.3 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.6 PVD24430.1 - 0.0039 16.6 27.5 0.0039 16.6 27.5 8.1 4 2 2 7 7 7 2 Growth-arrest specific micro-tubule binding SlyX PF04102.12 PVD24430.1 - 0.97 10.1 0.0 0.97 10.1 0.0 14.1 7 3 6 14 14 14 0 SlyX Rad52_Rad22 PF04098.15 PVD24431.1 - 5.8e-48 162.7 0.0 1.1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Flagellin_D3 PF08884.11 PVD24431.1 - 0.12 12.8 0.2 0.32 11.4 0.2 1.7 1 0 0 1 1 1 0 Flagellin D3 domain EGF_CA PF07645.15 PVD24432.1 - 5.1e-87 285.8 161.4 6.1e-11 42.3 8.5 12.3 12 1 1 13 13 13 11 Calcium-binding EGF domain cEGF PF12662.7 PVD24432.1 - 1e-57 191.6 106.1 1e-10 41.3 0.9 14.1 13 1 0 13 13 13 12 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD24432.1 - 3.8e-32 110.3 147.9 3.7e-09 36.7 4.3 12.5 9 3 2 11 11 11 8 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD24432.1 - 1.5e-16 60.4 141.7 1e-05 25.7 4.9 14.0 11 2 1 12 12 12 7 EGF-like domain EGF_3 PF12947.7 PVD24432.1 - 3.7e-13 49.4 137.8 0.0001 22.4 5.3 13.6 14 1 0 14 14 14 9 EGF domain hEGF PF12661.7 PVD24432.1 - 0.00011 22.7 11.1 0.0005 20.6 1.8 14.8 15 2 0 15 15 15 7 Human growth factor-like EGF adh_short PF00106.25 PVD24434.1 - 6.4e-35 120.4 0.4 8.7e-35 120.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD24434.1 - 2.3e-29 102.6 0.0 6.8e-29 101.1 0.3 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD24434.1 - 1e-08 35.3 1.6 4.2e-08 33.3 1.6 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD24434.1 - 0.0043 16.6 0.2 0.013 15.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD24434.1 - 0.16 11.0 0.1 0.49 9.4 0.1 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Atx10homo_assoc PF09759.9 PVD24435.1 - 1.9e-29 101.6 0.9 5.7e-29 100.0 0.9 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Codanin-1_C PF15296.6 PVD24437.1 - 0.025 14.7 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Codanin-1 C-terminus HicB-like_2 PF15970.5 PVD24437.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system KCNQ2_u3 PF16642.5 PVD24438.1 - 0.028 15.4 4.4 0.033 15.2 4.4 1.0 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 CcmD PF04995.14 PVD24438.1 - 2.1 8.5 4.9 3.1 8.0 2.7 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) wnt PF00110.19 PVD24439.1 - 1.8e-20 73.7 0.3 2.3e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 wnt family wnt PF00110.19 PVD24440.1 - 1.8e-60 205.2 22.6 1.9e-60 205.0 22.6 1.0 1 0 0 1 1 1 1 wnt family MbeD_MobD PF04899.12 PVD24441.1 - 2.4e-06 27.6 0.0 0.038 14.1 0.0 2.1 1 1 1 2 2 2 2 MbeD/MobD like Herpes_BLLF1 PF05109.13 PVD24441.1 - 0.034 12.2 3.2 0.035 12.1 3.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4688 PF15752.5 PVD24441.1 - 0.08 12.2 1.2 0.087 12.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) DUF1720 PF08226.11 PVD24441.1 - 0.14 12.6 4.7 0.18 12.2 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) wnt PF00110.19 PVD24442.1 - 2.7e-101 339.2 21.3 3.2e-101 339.0 21.3 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 PVD24443.1 - 7.9e-15 55.2 0.0 9.3e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 wnt family LRR_6 PF13516.6 PVD24448.1 - 1.1e-31 106.1 33.6 0.00071 19.4 0.0 12.1 13 0 0 13 13 13 10 Leucine Rich repeat LRR_4 PF12799.7 PVD24448.1 - 3.2e-20 71.9 24.0 0.0011 19.3 0.2 7.3 4 2 3 8 8 8 8 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PVD24448.1 - 1.2e-09 37.9 0.2 1.2e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 PVD24448.1 - 9.9e-09 34.8 20.7 0.11 12.3 0.3 7.6 5 3 3 8 8 8 5 Leucine rich repeat LRR_1 PF00560.33 PVD24448.1 - 1.4e-07 31.0 27.1 6.6 7.7 0.3 10.5 8 2 0 8 8 8 3 Leucine Rich Repeat F-box PF00646.33 PVD24448.1 - 1.6e-05 24.6 4.4 1.9e-05 24.4 0.1 3.2 2 0 0 2 2 2 1 F-box domain LRR_2 PF07723.13 PVD24448.1 - 0.0079 16.8 0.6 22 5.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 PVD24448.1 - 0.021 15.1 1.8 0.24 11.7 0.2 3.3 3 1 0 3 3 3 0 Ste50p, sterile alpha motif F5_F8_type_C PF00754.25 PVD24449.1 - 6.1e-05 23.1 0.0 9.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF2834 PF11196.8 PVD24449.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) DUF3180 PF11377.8 PVD24449.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) F5_F8_type_C PF00754.25 PVD24450.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 PVD24451.1 - 3.1e-14 53.2 0.1 0.00017 21.7 0.0 3.4 3 0 0 3 3 3 3 F5/8 type C domain DUF1654 PF07867.11 PVD24451.1 - 0.00015 21.4 0.0 5.6 6.8 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1654) DUF3331 PF11811.8 PVD24451.1 - 0.0022 17.8 1.9 2.4 8.1 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3331) nlz1 PF12402.8 PVD24451.1 - 0.034 14.6 0.1 5 7.6 0.0 3.1 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 UnbV_ASPIC PF07593.12 PVD24451.1 - 0.068 13.1 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 ASPIC and UnbV DUF1281_C PF18406.1 PVD24451.1 - 0.078 12.7 0.0 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Ferredoxin-like domain in Api92-like protein IMPa_N_2 PF18650.1 PVD24451.1 - 1.1 8.4 4.9 3.9 6.7 0.3 2.9 3 0 0 3 3 3 0 Immunomodulating metalloprotease N-terminal domain F5_F8_type_C PF00754.25 PVD24452.1 - 1.5e-09 38.1 0.1 1.3e-07 31.8 0.0 3.0 2 1 1 3 3 3 1 F5/8 type C domain CIMR PF00878.18 PVD24452.1 - 0.039 14.0 0.3 0.039 14.0 0.3 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Cytomega_TRL10 PF06084.11 PVD24452.1 - 0.11 12.5 1.0 6.7 6.7 0.1 3.1 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein F5_F8_type_C PF00754.25 PVD24453.1 - 8.2e-14 51.8 0.1 1.2e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain MACPF PF01823.19 PVD24454.1 - 3.7e-17 63.1 0.0 6.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 PVD24456.1 - 1.1e-21 77.9 0.0 1.5e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain SKG6 PF08693.10 PVD24456.1 - 0.0071 15.7 0.2 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 PVD24456.1 - 0.028 13.9 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity zf_C2H2_6 PF18450.1 PVD24457.1 - 0.18 11.6 0.8 0.39 10.5 0.8 1.6 1 0 0 1 1 1 0 Zinc Finger domain CECR6_TMEM121 PF14997.6 PVD24458.1 - 1.6e-35 122.7 4.4 1.6e-35 122.7 4.4 1.5 2 0 0 2 2 2 1 CECR6/TMEM121 family DUF981 PF06168.11 PVD24458.1 - 0.0022 18.0 0.5 0.0022 18.0 0.5 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF981) UPF0242 PF06785.11 PVD24459.1 - 0.0028 17.8 0.0 0.003 17.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CECR6_TMEM121 PF14997.6 PVD24459.1 - 0.0071 16.2 0.5 0.01 15.7 0.5 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family ABC_tran_Xtn PF12848.7 PVD24459.1 - 0.012 15.7 4.6 0.015 15.3 4.6 1.1 1 0 0 1 1 1 0 ABC transporter SieB PF14163.6 PVD24459.1 - 0.017 14.6 0.2 0.021 14.3 0.2 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4692 PF15763.5 PVD24459.1 - 0.023 15.2 0.1 0.026 15.0 0.1 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF2788 PF10981.8 PVD24459.1 - 0.071 13.1 2.1 0.088 12.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Ctr PF04145.15 PVD24459.1 - 0.11 13.2 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family CECR6_TMEM121 PF14997.6 PVD24460.1 - 1e-24 87.5 2.1 4.8e-24 85.3 0.2 2.1 1 1 1 2 2 2 1 CECR6/TMEM121 family DUF981 PF06168.11 PVD24460.1 - 0.014 15.4 1.1 0.018 14.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF981) COX15-CtaA PF02628.15 PVD24460.1 - 0.022 13.9 0.2 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Phage_holin_3_7 PF05449.11 PVD24460.1 - 0.13 12.3 2.6 0.16 12.0 0.2 2.4 2 1 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 CECR6_TMEM121 PF14997.6 PVD24461.1 - 5.1e-33 114.6 8.1 7.1e-33 114.1 8.1 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF4355 PF14265.6 PVD24461.1 - 1.3 9.2 3.7 2.1 8.6 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AdoHcyase PF05221.17 PVD24466.1 - 1.3e-121 405.4 0.0 2e-66 224.2 0.1 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PVD24466.1 - 1.1e-78 262.9 0.9 1.9e-78 262.1 0.9 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PVD24466.1 - 1.7e-09 37.3 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PVD24466.1 - 5.2e-05 22.9 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 PVD24466.1 - 0.0029 16.9 0.2 0.012 14.9 0.2 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 PVD24466.1 - 0.0047 17.2 0.2 0.011 16.0 0.2 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 PVD24466.1 - 0.0057 17.1 0.2 0.016 15.6 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 PVD24466.1 - 0.0058 16.7 0.1 0.016 15.3 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 PVD24466.1 - 0.022 14.5 0.6 0.35 10.6 0.1 2.2 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 PVD24466.1 - 0.067 11.9 0.0 0.22 10.2 0.0 1.7 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.21 PVD24466.1 - 0.074 12.3 0.7 0.25 10.6 0.7 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Nrf1_DNA-bind PF10491.9 PVD24467.1 - 1.9e-108 361.0 0.1 2.7e-108 360.6 0.1 1.2 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.9 PVD24467.1 - 0.028 15.1 19.3 0.11 13.1 2.1 3.9 2 1 1 3 3 3 0 Nrf1 activator activation site binding domain Cu_amine_oxidN2 PF02727.16 PVD24468.1 - 2e-07 31.1 0.0 3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 PVD24468.1 - 2e-07 30.3 0.1 2.9e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 PVD24469.1 - 2.2e-77 260.7 0.0 3.2e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Plant_NMP1 PF06694.11 PVD24469.1 - 5.7e-10 38.8 0.0 9.4e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) IFRD PF05004.13 PVD24470.1 - 1.6e-61 208.1 0.7 1.8e-61 207.9 0.7 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 PVD24470.1 - 2.7e-17 63.1 1.5 5.5e-17 62.1 1.5 1.6 1 0 0 1 1 1 1 Interferon-related protein conserved region VirK PF06903.12 PVD24470.1 - 0.041 14.0 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 VirK protein HEAT_EZ PF13513.6 PVD24470.1 - 0.23 12.0 1.6 0.45 11.1 0.3 2.1 2 0 0 2 2 2 0 HEAT-like repeat Sulfate_transp PF00916.20 PVD24474.1 - 8.9e-118 393.3 21.6 1.1e-117 393.0 21.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD24474.1 - 5.8e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain ATG7_N PF16420.5 PVD24475.1 - 3.8e-74 250.0 0.0 5.8e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 PVD24475.1 - 1.6e-47 161.9 0.0 4e-47 160.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family Kelch_3 PF13415.6 PVD24475.1 - 3.9e-33 113.1 1.7 1.2e-05 25.5 0.0 7.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD24475.1 - 6.9e-32 108.9 0.4 4.3e-05 23.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PVD24475.1 - 1.9e-25 88.6 0.0 3.4e-05 23.7 0.0 7.0 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD24475.1 - 3.9e-21 74.6 0.8 0.012 15.9 0.0 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PVD24475.1 - 1.1e-20 72.9 1.4 3e-05 23.5 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 PVD24475.1 - 2.1e-15 56.0 0.2 0.011 15.7 0.0 6.6 6 0 0 6 6 6 4 Kelch motif fn3 PF00041.21 PVD24475.1 - 7.8e-10 39.0 0.4 0.0024 18.2 0.0 3.9 4 0 0 4 4 4 2 Fibronectin type III domain Pkinase PF00069.25 PVD24476.1 - 9e-64 215.4 0.0 1.4e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24476.1 - 9.1e-38 130.0 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 PVD24476.1 - 7.4e-28 96.2 35.2 1.6e-14 53.5 10.4 3.0 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 PVD24476.1 - 1.2e-06 29.1 1.8 2.6e-06 28.0 1.8 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Zf_RING PF16744.5 PVD24476.1 - 0.01 15.9 13.2 0.18 12.0 3.2 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger FTA2 PF13095.6 PVD24476.1 - 0.034 13.8 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PVD24476.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 PVD24476.1 - 0.066 13.5 22.2 1 9.7 7.8 2.8 2 0 0 2 2 2 0 C1 domain Thioredoxin_8 PF13905.6 PVD24476.1 - 0.099 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Haspin_kinase PF12330.8 PVD24476.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain C2 PF00168.30 PVD24476.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 C2 domain APH PF01636.23 PVD24476.1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CpG_bind_C PF12269.8 PVD24480.1 - 7.1e-100 333.6 11.0 7.1e-100 333.6 11.0 3.1 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 PVD24480.1 - 5e-15 55.2 20.6 5e-15 55.2 20.6 4.1 4 1 1 5 5 5 1 CXXC zinc finger domain PHD PF00628.29 PVD24480.1 - 2.9e-08 33.5 14.0 2.9e-08 33.5 14.0 4.0 3 1 1 4 4 4 1 PHD-finger PHD_3 PF13922.6 PVD24480.1 - 0.0083 16.5 1.1 0.0083 16.5 1.1 3.1 4 0 0 4 4 4 1 PHD domain of transcriptional enhancer, Asx WGG PF10273.9 PVD24480.1 - 0.025 15.2 0.4 0.058 14.1 0.4 1.6 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 PRA1 PF03208.19 PVD24481.1 - 9.9e-37 125.7 6.1 1.1e-36 125.5 6.1 1.0 1 0 0 1 1 1 1 PRA1 family protein NnrS PF05940.12 PVD24481.1 - 0.0013 18.2 5.2 0.0015 18.0 5.2 1.1 1 0 0 1 1 1 1 NnrS protein EI24 PF07264.11 PVD24481.1 - 0.076 13.3 0.5 0.076 13.3 0.5 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Peptidase_U4 PF03419.13 PVD24481.1 - 0.11 11.8 6.8 0.17 11.1 6.8 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA GPI2 PF06432.11 PVD24481.1 - 1.2 8.6 5.3 0.84 9.0 4.1 1.3 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.24 PVD24481.1 - 5.1 6.8 8.0 11 5.8 7.9 1.5 1 1 1 2 2 2 0 Fatty acid desaturase SIP1 PF04938.12 PVD24482.1 - 1.2e-62 211.5 0.1 1.4e-62 211.3 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) RabGAP-TBC PF00566.18 PVD24483.1 - 1.2e-37 129.7 1.0 5.2e-37 127.6 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4682 PF15733.5 PVD24483.1 - 9.6e-13 48.8 1.1 9.6e-13 48.8 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4682) FEZ PF07763.13 PVD24483.1 - 0.011 15.5 0.2 0.011 15.5 0.2 2.5 3 0 0 3 3 3 0 FEZ-like protein CytochromB561_N PF09786.9 PVD24484.1 - 7.9e-71 239.8 0.4 1.2e-70 239.2 0.4 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal COG5 PF10392.9 PVD24485.1 - 1.3e-13 51.2 1.3 1.3e-13 51.2 1.3 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 PVD24485.1 - 1e-05 25.5 0.4 1e-05 25.5 0.4 2.4 3 0 0 3 3 3 1 Vps51/Vps67 DUF190 PF02641.15 PVD24485.1 - 0.031 14.6 0.2 0.08 13.3 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 DUF4132 PF13569.6 PVD24485.1 - 0.069 12.9 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF758 PF05527.11 PVD24485.1 - 0.074 13.0 3.1 0.14 12.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF758) CLZ PF16526.5 PVD24485.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 7TMR-HDED PF07697.11 PVD24485.1 - 0.22 11.6 8.5 0.35 10.9 2.0 2.6 1 1 0 2 2 2 0 7TM-HD extracellular Dus PF01207.17 PVD24486.1 - 3.2e-69 233.4 0.1 4e-69 233.1 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PVD24486.1 - 6.2e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 PVD24486.1 - 0.00047 19.5 0.0 0.00072 18.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Pkinase PF00069.25 PVD24487.1 - 1.3e-46 159.1 0.0 4e-46 157.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24487.1 - 1.2e-39 136.2 0.0 2.7e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PVD24487.1 - 5.9e-33 112.4 39.3 6.2e-11 41.9 1.3 6.8 2 1 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PVD24487.1 - 2.7e-30 103.9 42.0 1.7e-06 28.2 2.1 7.9 5 1 3 8 8 8 8 Leucine Rich repeats (2 copies) Roc PF08477.13 PVD24487.1 - 1.4e-26 93.1 0.0 1.6e-25 89.6 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 PVD24487.1 - 2.6e-23 82.8 0.0 6.1e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 PVD24487.1 - 6.7e-12 45.3 0.0 1.7e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_9 PF14580.6 PVD24487.1 - 2.4e-07 30.4 15.1 0.044 13.3 0.2 4.6 1 1 3 4 4 4 4 Leucine-rich repeat Ank_2 PF12796.7 PVD24487.1 - 1.8e-06 28.5 0.0 8.3e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) LRR_1 PF00560.33 PVD24487.1 - 2.7e-06 27.2 32.4 0.96 10.2 0.0 10.1 10 1 0 10 10 9 3 Leucine Rich Repeat Arf PF00025.21 PVD24487.1 - 0.0036 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_4 PF13637.6 PVD24487.1 - 0.006 17.1 0.0 0.036 14.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LRR_6 PF13516.6 PVD24487.1 - 0.0064 16.4 45.2 8.8 6.7 1.0 11.8 11 0 0 11 11 11 1 Leucine Rich repeat MMR_HSR1 PF01926.23 PVD24487.1 - 0.0073 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ank_3 PF13606.6 PVD24487.1 - 0.0099 16.3 0.0 9.5 7.2 0.0 3.4 2 0 0 2 2 2 0 Ankyrin repeat DUF3337 PF11816.8 PVD24487.1 - 0.028 14.3 0.3 0.072 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Ank_5 PF13857.6 PVD24487.1 - 0.037 14.3 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Gtr1_RagA PF04670.12 PVD24487.1 - 0.057 12.8 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PVD24487.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain An_peroxidase PF03098.15 PVD24488.1 - 4.3e-100 335.8 0.0 5.3e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Ank_5 PF13857.6 PVD24488.1 - 0.056 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD24488.1 - 0.067 13.8 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) An_peroxidase PF03098.15 PVD24489.1 - 5e-93 312.5 0.0 9.2e-55 186.2 0.0 2.0 2 0 0 2 2 2 2 Animal haem peroxidase WASH-7_N PF14745.6 PVD24490.1 - 8.3e-217 721.2 7.9 8.3e-217 721.2 7.9 2.0 2 0 0 2 2 2 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 PVD24490.1 - 3.9e-171 568.8 5.8 8.1e-171 567.8 5.8 1.5 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 PVD24490.1 - 2.3e-71 239.1 1.7 5.5e-71 237.9 1.7 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal ZapA PF05164.13 PVD24490.1 - 2.1 8.8 5.2 2.1 8.8 0.5 3.4 4 0 0 4 4 4 0 Cell division protein ZapA TRAM_LAG1_CLN8 PF03798.16 PVD24491.1 - 1.7e-11 44.2 21.4 1.7e-11 44.2 21.4 1.5 2 0 0 2 2 2 1 TLC domain ECH_1 PF00378.20 PVD24492.1 - 4e-49 167.2 0.2 4.4e-49 167.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD24492.1 - 3.2e-23 82.8 0.1 6e-21 75.3 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Fasciclin PF02469.22 PVD24493.1 - 3.7e-75 250.2 1.9 2.7e-17 63.2 0.1 6.0 5 1 0 5 5 5 5 Fasciclin domain EGF_3 PF12947.7 PVD24493.1 - 3e-42 142.5 240.6 1.4e-07 31.6 10.5 15.9 16 1 0 16 16 16 10 EGF domain FXa_inhibition PF14670.6 PVD24493.1 - 0.00011 22.5 22.3 0.00096 19.4 8.3 16.7 11 5 4 16 16 16 8 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 PVD24493.1 - 0.00015 21.9 19.1 0.00036 20.7 3.7 16.3 11 5 5 16 16 16 4 Calcium-binding EGF domain cEGF PF12662.7 PVD24493.1 - 0.0097 15.8 1.6 0.0097 15.8 1.6 16.2 17 0 0 17 17 17 8 Complement Clr-like EGF-like EGF PF00008.27 PVD24493.1 - 0.0098 16.2 5.2 0.0098 16.2 5.2 16.0 15 1 0 15 15 15 6 EGF-like domain Peptidase_M20 PF01546.28 PVD24494.1 - 2.9e-34 118.6 0.0 3.8e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PVD24494.1 - 2.9e-13 49.7 0.0 5.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PVD24494.1 - 0.00072 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Trypan_PARP PF05887.11 PVD24497.1 - 2.8 7.9 8.8 3.3 7.7 8.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 PVD24502.1 - 3.7e-36 124.8 3.1 5.9e-32 111.0 0.3 2.3 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD24503.1 - 3.9e-40 138.0 4.5 1.6e-34 119.5 0.1 3.1 3 0 0 3 3 2 2 Cytochrome P450 Caldesmon PF02029.15 PVD24503.1 - 1.5e-08 33.9 43.3 2.6e-08 33.1 43.3 1.4 1 0 0 1 1 1 1 Caldesmon Apt1 PF10351.9 PVD24503.1 - 0.0047 15.8 19.4 0.0066 15.4 19.4 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Mem_trans PF03547.18 PVD24503.1 - 0.034 12.6 1.3 0.038 12.4 1.3 1.3 1 0 0 1 1 1 0 Membrane transport protein SLC12 PF03522.15 PVD24503.1 - 0.083 11.9 30.9 0.15 11.1 30.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 PVD24503.1 - 0.26 10.0 32.8 0.47 9.2 32.8 1.4 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 PVD24503.1 - 0.51 9.4 23.8 0.81 8.7 23.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF262 PF03235.14 PVD24503.1 - 0.63 10.2 18.8 1.7 8.8 18.8 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF262 Hid1 PF12722.7 PVD24503.1 - 1.2 7.2 30.1 1.8 6.6 30.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PVD24503.1 - 1.5 7.0 59.4 0.4 8.9 56.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 PVD24503.1 - 2.1 6.4 54.2 3.2 5.9 54.2 1.2 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.22 PVD24504.1 - 6.8e-34 117.4 1.0 4.9e-33 114.6 0.9 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD24505.1 - 2.5e-37 128.7 3.9 4.4e-30 104.8 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 ALP_N PF17989.1 PVD24505.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Actin like proteins N terminal domain p450 PF00067.22 PVD24506.1 - 1e-36 126.7 6.7 1.7e-35 122.7 6.7 2.1 1 1 0 1 1 1 1 Cytochrome P450 Telomere_reg-2 PF10193.9 PVD24506.1 - 0.16 12.4 0.2 0.39 11.2 0.2 1.6 1 0 0 1 1 1 0 Telomere length regulation protein p450 PF00067.22 PVD24508.1 - 1.4e-38 132.9 3.9 1.9e-38 132.4 3.9 1.1 1 0 0 1 1 1 1 Cytochrome P450 YAF2_RYBP PF17219.3 PVD24509.1 - 3.2e-17 61.8 0.6 6.6e-17 60.8 0.6 1.6 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 PVD24509.1 - 1.3e-09 37.2 2.1 2.6e-09 36.2 2.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 PVD24509.1 - 0.0034 17.7 2.4 0.0074 16.6 1.8 1.8 2 0 0 2 2 2 1 C1 domain zf-HIT PF04438.16 PVD24509.1 - 0.51 10.3 4.4 0.82 9.6 4.4 1.2 1 0 0 1 1 1 0 HIT zinc finger Bmt2 PF11968.8 PVD24510.1 - 2.7e-05 24.1 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 FOXP-CC PF16159.5 PVD24512.1 - 3.3e-30 104.5 5.2 6.3e-30 103.6 5.2 1.5 1 0 0 1 1 1 1 FOXP coiled-coil domain Forkhead PF00250.18 PVD24512.1 - 1.3e-27 95.9 0.2 2.7e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain Zap1_zf2 PF18217.1 PVD24512.1 - 0.041 13.9 0.4 0.074 13.1 0.4 1.4 1 0 0 1 1 1 0 Zap1 zinc finger 2 APG6_N PF17675.1 PVD24512.1 - 0.13 12.8 0.9 0.2 12.2 0.1 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Adeno_E3_CR2 PF02439.15 PVD24514.1 - 0.012 15.3 3.3 0.023 14.5 3.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 PVD24514.1 - 0.032 14.5 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Homez PF11569.8 PVD24514.1 - 0.032 13.7 1.0 0.053 13.0 1.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Orthoreo_P10 PF07204.11 PVD24514.1 - 0.067 13.2 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SNF PF00209.18 PVD24515.1 - 8.3e-214 711.1 44.0 4.2e-213 708.8 44.0 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Exostosin PF03016.15 PVD24516.1 - 3.4e-08 33.0 0.0 5.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Glyco_trans_1_4 PF13692.6 PVD24516.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 UPF0020 PF01170.18 PVD24519.1 - 8.1e-27 94.2 0.0 7.5e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 PVD24519.1 - 6.5e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 2 0 0 2 2 2 1 THUMP domain AviRa PF11599.8 PVD24519.1 - 0.0015 18.0 0.1 0.005 16.3 0.0 1.9 2 0 0 2 2 2 1 RRNA methyltransferase AviRa N6_Mtase PF02384.16 PVD24519.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 N-6 DNA Methylase TBX PF12598.8 PVD24519.1 - 3.1 8.6 6.4 0.34 11.7 1.8 1.7 2 0 0 2 2 2 0 T-box transcription factor AAA_16 PF13191.6 PVD24520.1 - 2.2e-05 24.9 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 PVD24520.1 - 0.00028 20.7 0.0 0.00073 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PVD24520.1 - 0.00033 21.1 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD24520.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 PVD24520.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 PVD24520.1 - 0.0036 17.7 0.0 0.0067 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD24520.1 - 0.0036 17.8 0.0 0.0088 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PVD24520.1 - 0.0038 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 PVD24520.1 - 0.0039 17.5 0.0 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PVD24520.1 - 0.0086 16.6 0.0 0.023 15.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 PVD24520.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PVD24520.1 - 0.032 14.6 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 PVD24520.1 - 0.037 14.0 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 PVD24520.1 - 0.038 13.9 0.1 0.078 12.9 0.1 1.7 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 PVD24520.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PIF1 PF05970.14 PVD24520.1 - 0.046 12.9 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase KTI12 PF08433.10 PVD24520.1 - 0.058 12.8 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 PVD24520.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PVD24520.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 PVD24520.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 PVD24520.1 - 0.15 12.1 0.1 15 5.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain XhlA PF10779.9 PVD24521.1 - 2.6 8.3 3.5 5.1 7.4 3.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Mon1 PF03164.14 PVD24522.1 - 3.2e-149 497.4 2.6 3.8e-149 497.2 2.6 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S26e PF01283.19 PVD24522.1 - 0.07 13.6 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S26e PP2C PF00481.21 PVD24523.1 - 1.7e-27 96.7 0.0 4.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PVD24523.1 - 2.3e-06 27.7 0.0 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF4147 PF13660.6 PVD24524.1 - 1.9e-44 151.9 2.5 6.8e-34 117.4 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4147) MOFRL PF05161.13 PVD24524.1 - 7.2e-27 93.7 1.2 1.2e-26 93.0 1.2 1.4 1 0 0 1 1 1 1 MOFRL family DUF4147 PF13660.6 PVD24525.1 - 4.7e-72 242.3 0.1 7.9e-72 241.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 PVD24525.1 - 7.6e-35 119.4 1.2 1.5e-34 118.4 1.2 1.6 1 0 0 1 1 1 1 MOFRL family DUF896 PF05979.12 PVD24525.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) QslA_E PF18226.1 PVD24525.1 - 0.12 12.4 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 LasR-specific antiactivator QslA chain E VWA PF00092.28 PVD24526.1 - 8.9e-54 182.4 7.8 6.3e-29 101.5 1.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24526.1 - 1.3e-30 106.2 1.4 6e-14 52.6 0.1 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD24526.1 - 1.4e-12 47.8 0.6 7.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD24526.1 - 2.4e-12 46.7 2.6 4e-06 26.4 0.8 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF2201 PF09967.9 PVD24526.1 - 0.0001 22.4 1.1 0.27 11.4 0.1 2.7 2 0 0 2 2 2 2 VWA-like domain (DUF2201) Hypoth_Ymh PF09509.10 PVD24526.1 - 0.046 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) VWA PF00092.28 PVD24527.1 - 9.7e-24 84.5 1.3 9.7e-24 84.5 1.3 1.9 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24527.1 - 3.1e-14 53.5 3.4 1.1e-13 51.7 1.1 2.9 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD24527.1 - 0.0079 16.2 0.5 0.019 14.9 0.5 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Sulfatase PF00884.23 PVD24528.1 - 6.5e-73 245.8 0.0 1.4e-72 244.8 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 PVD24528.1 - 4e-26 92.2 0.4 6e-26 91.6 0.4 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 PVD24528.1 - 6.2e-07 29.3 0.3 1.3e-05 25.0 0.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 PVD24528.1 - 0.014 15.6 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Toxin_8 PF07365.12 PVD24528.1 - 0.62 10.3 2.5 9.4 6.5 1.2 2.4 2 0 0 2 2 2 0 Alpha conotoxin precursor Usp PF00582.26 PVD24530.1 - 1.7e-15 57.8 0.0 2.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4729 PF15866.5 PVD24530.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4729) 7tm_1 PF00001.21 PVD24531.1 - 3.6e-28 98.6 0.3 2.3e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD24531.1 - 2.2e-10 40.3 5.0 1.4e-05 24.6 0.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD24531.1 - 0.016 14.9 1.5 0.016 14.9 1.5 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Podoplanin PF05808.11 PVD24531.1 - 0.031 14.4 2.1 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 Podoplanin NERD PF08378.11 PVD24532.1 - 6.6e-06 26.5 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain DUF148 PF02520.17 PVD24532.1 - 0.069 13.3 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 S1FA PF04689.13 PVD24533.1 - 0.0061 16.7 0.1 0.0098 16.0 0.1 1.3 1 0 0 1 1 1 1 DNA binding protein S1FA F5_F8_type_C PF00754.25 PVD24533.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain MAP17 PF15807.5 PVD24533.1 - 0.026 14.7 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 PVD24533.1 - 0.076 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 FAM176 family OAD_gamma PF04277.13 PVD24533.1 - 0.087 13.4 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Globin PF00042.22 PVD24535.1 - 5.9e-22 78.3 0.2 9.1e-22 77.7 0.0 1.4 2 0 0 2 2 2 1 Globin Proteasome PF00227.26 PVD24536.1 - 7.3e-60 201.7 0.0 9.4e-60 201.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PVD24536.1 - 7.5e-14 51.1 0.0 1.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MARVEL PF01284.23 PVD24538.1 - 6e-21 75.0 9.9 7.4e-21 74.7 9.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF5418 PF17439.2 PVD24538.1 - 0.047 13.8 2.0 0.078 13.1 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5418) Chol_subst-bind PF09129.11 PVD24538.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding MTS PF05175.14 PVD24539.1 - 1.8e-14 53.6 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PVD24539.1 - 3.1e-11 43.8 0.0 5.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD24539.1 - 5.2e-11 42.6 0.0 6.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PVD24539.1 - 2e-08 34.1 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PVD24539.1 - 7.6e-08 33.0 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PVD24539.1 - 7.9e-07 28.9 0.1 2.1e-06 27.5 0.0 1.5 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 PVD24539.1 - 1.1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD24539.1 - 1.2e-06 28.4 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PVD24539.1 - 1.8e-06 27.6 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 PVD24539.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 PVD24539.1 - 0.00035 21.6 0.0 0.00079 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PVD24539.1 - 0.00065 18.8 0.0 0.00091 18.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 PVD24539.1 - 0.00069 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 PVD24539.1 - 0.0025 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD24539.1 - 0.0028 17.1 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 PVD24539.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MetW PF07021.12 PVD24539.1 - 0.0035 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 PVD24539.1 - 0.0041 17.1 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 PVD24539.1 - 0.033 14.8 0.0 0.078 13.6 0.0 1.7 1 0 0 1 1 1 0 PrmC N-terminal domain Methyltransf_2 PF00891.18 PVD24539.1 - 0.034 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 PVD24539.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_33 PF10017.9 PVD24539.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent N6_Mtase PF02384.16 PVD24539.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase LacAB_rpiB PF02502.18 PVD24539.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribose/Galactose Isomerase tRNA_U5-meth_tr PF05958.11 PVD24539.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Eco57I PF07669.11 PVD24539.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Ubie_methyltran PF01209.18 PVD24539.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PVD24539.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) F5_F8_type_C PF00754.25 PVD24543.1 - 0.0037 17.4 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain Apolipoprotein PF01442.18 PVD24544.1 - 0.11 12.3 0.5 0.15 11.9 0.5 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2207 PF09972.9 PVD24544.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Laminin_EGF PF00053.24 PVD24544.1 - 0.23 11.6 66.0 6.2 7.0 22.2 5.0 2 1 2 4 4 4 0 Laminin EGF domain Laminin_EGF PF00053.24 PVD24546.1 - 0.00071 19.7 194.6 2 8.6 6.3 11.9 1 1 11 12 12 12 3 Laminin EGF domain Sigma_reg_N PF13800.6 PVD24546.1 - 0.15 12.3 2.0 0.15 12.3 0.7 1.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Laminin_EGF PF00053.24 PVD24547.1 - 0.023 14.8 116.4 0.77 9.9 21.5 8.3 2 2 5 7 7 7 0 Laminin EGF domain Sigma_reg_N PF13800.6 PVD24547.1 - 0.058 13.7 1.4 0.067 13.5 0.6 1.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ig_2 PF13895.6 PVD24548.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 PVD24549.1 - 0.031 14.9 0.0 0.071 13.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain LAT PF15234.6 PVD24549.1 - 1 9.1 7.2 0.21 11.3 1.7 2.1 1 1 0 2 2 2 0 Linker for activation of T-cells V-set PF07686.17 PVD24550.1 - 0.00084 19.5 0.1 0.0022 18.1 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD24550.1 - 0.02 15.5 0.5 0.043 14.4 0.0 2.0 2 1 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 PVD24550.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain VIR_N PF15912.5 PVD24550.1 - 2.5 7.6 14.6 3.2 7.3 14.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Phenyl_P_gamma PF09662.10 PVD24551.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Ig_2 PF13895.6 PVD24552.1 - 0.031 14.6 0.4 0.076 13.4 0.0 2.0 2 1 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 PVD24552.1 - 0.042 14.4 0.5 0.17 12.5 0.2 2.3 3 1 0 3 3 3 0 Immunoglobulin domain RhoGEF PF00621.20 PVD24555.1 - 3.1e-27 96.0 0.0 4.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PVD24555.1 - 0.0018 18.7 0.0 0.0047 17.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 PVD24555.1 - 0.0021 18.2 0.0 0.009 16.1 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Aha1_N PF09229.11 PVD24555.1 - 0.049 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal ABC_membrane_2 PF06472.15 PVD24556.1 - 5.9e-97 324.3 11.4 8e-97 323.8 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PVD24556.1 - 7.2e-18 65.4 0.0 1.8e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PVD24556.1 - 7.9e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD24556.1 - 0.002 17.6 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PVD24556.1 - 0.0031 18.0 1.2 0.016 15.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PVD24556.1 - 0.0094 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Adeno_IVa2 PF02456.15 PVD24556.1 - 0.019 13.8 0.6 0.048 12.4 0.2 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_29 PF13555.6 PVD24556.1 - 0.022 14.5 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ARID PF01388.21 PVD24556.1 - 0.15 12.8 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain FAM212 PF15342.6 PVD24557.1 - 0.11 12.3 1.4 0.52 10.1 1.4 2.2 1 0 0 1 1 1 0 FAM212 family Sugar_tr PF00083.24 PVD24558.1 - 3.9e-80 269.9 11.9 3.2e-55 187.8 1.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD24558.1 - 8.1e-12 44.7 10.8 1.1e-11 44.3 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 PVD24558.1 - 0.39 11.3 10.2 0.96 10.0 10.2 1.7 1 1 0 1 1 1 0 Plexin repeat AAA PF00004.29 PVD24562.1 - 4.6e-11 43.3 0.0 1.1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Collagen PF01391.18 PVD24562.1 - 0.00024 20.8 14.2 0.0005 19.8 14.2 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) IQ PF00612.27 PVD24562.1 - 0.0017 18.0 0.8 0.0041 16.8 0.8 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 PVD24562.1 - 0.0069 16.8 0.4 0.037 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 PVD24562.1 - 0.026 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2344 PF10105.9 PVD24562.1 - 0.068 13.0 0.3 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) AP3D1 PF06375.11 PVD24562.1 - 0.67 10.2 14.3 3.1 8.0 14.3 2.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Holin_BhlA PF10960.8 PVD24562.1 - 1.3 9.1 3.7 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 BhlA holin family Bap31 PF05529.12 PVD24563.1 - 1.1e-16 61.0 0.2 1.1e-16 61.0 0.2 1.9 2 1 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 PVD24563.1 - 4.8e-14 52.1 7.4 4.8e-14 52.1 7.4 2.6 2 1 1 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain FHIPEP PF00771.20 PVD24563.1 - 0.00062 18.4 2.0 0.00081 18.0 2.0 1.0 1 0 0 1 1 1 1 FHIPEP family UPF0242 PF06785.11 PVD24563.1 - 0.0099 16.0 7.6 0.014 15.5 7.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF2937 PF11157.8 PVD24563.1 - 0.14 11.9 0.3 0.14 11.9 0.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) YabA PF06156.13 PVD24563.1 - 0.21 12.2 11.4 0.068 13.8 4.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA AAA_31 PF13614.6 PVD24563.1 - 0.22 11.4 1.6 0.3 11.0 1.6 1.2 1 0 0 1 1 1 0 AAA domain O-antigen_lig PF13425.6 PVD24563.1 - 0.31 9.8 2.5 0.37 9.5 2.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 PVD24563.1 - 0.38 9.1 1.1 0.43 8.9 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF948 PF06103.11 PVD24563.1 - 1.1 9.5 5.8 1.9 8.8 0.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 PVD24563.1 - 1.3 8.9 8.5 0.1 12.4 2.3 2.0 2 0 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 PVD24563.1 - 1.5 6.6 10.4 0.5 8.2 0.4 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 PVD24563.1 - 1.8 8.6 4.2 2.2 8.3 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3539 PF12058.8 PVD24563.1 - 2.4 8.4 5.4 0.85 9.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3539) MscS_TM PF12794.7 PVD24563.1 - 5.4 5.8 8.1 8.1 5.2 7.6 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF730 PF05325.11 PVD24563.1 - 9.8 6.2 9.8 2.1 8.4 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF730) DUF4876 PF16215.5 PVD24564.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4876) DUF3715 PF12509.8 PVD24565.1 - 2.8e-34 118.3 0.1 1.1e-32 113.1 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3715) TSP_1 PF00090.19 PVD24566.1 - 3.7e-43 145.5 75.7 3.6e-13 49.5 8.5 5.9 6 0 0 6 6 6 5 Thrombospondin type 1 domain CCDC66 PF15236.6 PVD24567.1 - 3.4e-25 88.7 29.0 3.4e-25 88.7 29.0 6.7 4 3 2 6 6 6 1 Coiled-coil domain-containing protein 66 MRP-L46 PF11788.8 PVD24568.1 - 2.8e-15 57.1 0.2 4.8e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 PVD24568.1 - 3.6e-05 23.8 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RPAP3_C PF13877.6 PVD24569.1 - 1.2e-21 77.1 0.2 3e-21 75.8 0.2 1.8 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 PVD24569.1 - 9.4e-18 63.2 3.6 4.9e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD24569.1 - 1e-13 50.3 2.5 0.00034 20.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD24569.1 - 4.2e-09 36.0 0.9 0.0027 17.3 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 PVD24569.1 - 5.1e-09 35.7 0.2 0.11 12.8 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD24569.1 - 4.2e-07 30.0 1.3 0.0041 17.2 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD24569.1 - 3.9e-05 24.2 0.5 0.077 13.7 1.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD24569.1 - 0.0005 20.7 1.0 2.5 9.1 0.4 3.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD24569.1 - 0.00067 19.9 1.6 0.04 14.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD24569.1 - 0.00088 19.1 0.2 0.029 14.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD24569.1 - 0.005 17.3 2.1 0.22 12.1 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD24569.1 - 0.0071 16.4 3.3 0.047 13.8 0.6 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 PVD24569.1 - 0.45 10.8 4.7 39 4.6 0.0 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ABC_trans_CmpB PF06541.11 PVD24570.1 - 1e-07 32.3 8.3 1.7e-07 31.6 8.3 1.3 1 0 0 1 1 1 1 Putative ABC-transporter type IV DUF3021 PF11457.8 PVD24570.1 - 0.051 13.9 3.3 0.075 13.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Lig_chan-Glu_bd PF10613.9 PVD24571.1 - 5.7e-25 87.7 0.0 9.8e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD24571.1 - 2.6e-24 85.8 0.0 6.3e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD24571.1 - 6.4e-18 65.0 0.0 1.3e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 UPF0242 PF06785.11 PVD24571.1 - 0.64 10.1 2.8 21 5.1 0.3 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF442 PF04273.13 PVD24572.1 - 1.4e-14 54.1 0.0 1.5e-05 25.0 0.0 3.4 3 0 0 3 3 3 3 Putative phosphatase (DUF442) DSPc PF00782.20 PVD24572.1 - 0.033 14.0 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PVD24572.1 - 0.08 13.1 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF442 PF04273.13 PVD24573.1 - 2.4e-09 37.2 0.0 2.6e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 Putative phosphatase (DUF442) PTPlike_phytase PF14566.6 PVD24573.1 - 0.0056 16.8 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 PVD24573.1 - 0.11 12.3 0.0 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD24573.1 - 0.12 11.9 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Cadherin PF00028.17 PVD24574.1 - 0 1525.1 155.4 4.1e-23 81.6 0.3 32.2 31 1 1 32 32 32 32 Cadherin domain Cadherin_3 PF16184.5 PVD24574.1 - 4.4e-51 171.6 85.6 0.001 19.0 0.4 29.9 30 2 3 33 33 33 17 Cadherin-like Cadherin_2 PF08266.12 PVD24574.1 - 5.3e-24 83.9 0.0 0.14 12.1 0.0 17.4 21 0 0 21 21 21 4 Cadherin-like Cadherin_4 PF17803.1 PVD24574.1 - 9.8e-09 35.7 454.3 0.011 16.4 4.6 33.2 31 1 1 32 32 32 19 Bacterial cadherin-like domain RMI1_C PF16099.5 PVD24574.1 - 0.0058 16.5 9.0 1.1 9.1 0.1 5.3 3 1 1 4 4 4 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Y_Y_Y PF07495.13 PVD24574.1 - 0.09 12.8 0.0 3.3e+02 1.3 0.0 6.4 8 0 0 8 8 8 0 Y_Y_Y domain DUF3377 PF11857.8 PVD24574.1 - 3.4 7.6 5.6 23 5.0 5.6 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) bZIP_2 PF07716.15 PVD24575.1 - 6.5e-11 42.1 11.0 1.4e-10 41.1 11.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD24575.1 - 0.0014 18.6 7.7 0.0034 17.4 7.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF3402 PF11882.8 PVD24576.1 - 2.7e-106 356.5 11.0 4.7e-67 227.1 1.3 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 PVD24576.1 - 2.5e-43 148.3 0.2 4.1e-43 147.6 0.2 1.3 1 0 0 1 1 1 1 N1221-like protein Toxin_26 PF08097.11 PVD24577.1 - 0.05 14.3 1.0 20 6.1 0.1 2.7 2 0 0 2 2 2 0 Conotoxin T-superfamily Tafi-CsgC PF10610.9 PVD24577.1 - 0.055 13.7 3.8 1.3 9.3 0.2 2.3 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein SLD5_C PF16922.5 PVD24577.1 - 0.22 11.7 0.0 96 3.3 0.0 3.1 3 0 0 3 3 3 0 DNA replication complex GINS protein SLD5 C-terminus zf-H2C2_2 PF13465.6 PVD24578.1 - 1.1e-15 57.3 62.9 0.00013 22.2 1.7 9.1 9 0 0 9 9 9 5 Zinc-finger double domain BTB PF00651.31 PVD24578.1 - 1.8e-14 53.9 0.1 8.6e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD24578.1 - 1.1e-13 51.2 0.2 3.3e-13 49.6 0.2 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2 PF00096.26 PVD24578.1 - 5e-11 42.4 73.0 0.00018 21.8 1.4 8.7 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD24578.1 - 2.5e-08 34.0 69.5 0.0069 17.1 1.5 8.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD24578.1 - 1.8e-05 24.9 19.1 0.026 14.8 0.2 5.6 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PVD24578.1 - 0.00015 21.4 2.2 0.00015 21.4 2.2 7.9 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 PVD24578.1 - 0.0028 17.2 21.3 0.13 11.9 0.0 4.9 4 1 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 PVD24578.1 - 0.011 16.1 6.9 0.067 13.5 2.5 2.9 2 0 0 2 2 2 0 BolA-like protein zf-met PF12874.7 PVD24578.1 - 0.018 15.5 0.2 0.018 15.5 0.2 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF4791 PF16039.5 PVD24578.1 - 0.031 13.8 0.9 0.074 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) TerY_C PF15616.6 PVD24578.1 - 0.039 14.1 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain GAGA PF09237.11 PVD24578.1 - 0.18 11.6 0.1 0.18 11.6 0.1 4.1 2 2 1 4 4 4 0 GAGA factor zf-piccolo PF05715.13 PVD24578.1 - 3.9 7.7 6.5 0.53 10.5 0.3 2.9 3 0 0 3 3 3 0 Piccolo Zn-finger HypA PF01155.19 PVD24578.1 - 6.8 6.8 14.1 4.4 7.4 3.5 3.2 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF563 PF04577.14 PVD24579.1 - 1.9e-23 83.7 0.2 2.9e-23 83.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FemAB PF02388.16 PVD24579.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 FemAB family Lig_chan-Glu_bd PF10613.9 PVD24579.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site MCM PF00493.23 PVD24580.1 - 4.7e-79 264.6 0.2 6.5e-70 234.7 0.0 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 PVD24580.1 - 2.2e-37 127.7 0.0 4e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PVD24580.1 - 3.2e-30 104.4 1.8 1.1e-29 102.7 1.8 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PVD24580.1 - 3.6e-18 66.1 0.6 1.3e-17 64.3 0.6 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 PVD24580.1 - 1.5e-13 51.3 17.1 3.6e-13 50.1 15.0 2.5 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 PVD24580.1 - 5.8e-05 22.6 0.0 0.0089 15.4 0.0 2.8 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PVD24580.1 - 0.00038 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 PVD24580.1 - 0.0013 18.6 0.2 0.0064 16.3 0.1 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 PVD24580.1 - 0.0037 17.1 0.0 0.032 14.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3045 PF11243.8 PVD24580.1 - 0.0083 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3045) AAA_2 PF07724.14 PVD24580.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zn-ribbon_8 PF09723.10 PVD24580.1 - 0.1 12.7 1.4 0.26 11.5 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 PVD24580.1 - 1.2 8.9 2.4 25 4.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Pkinase PF00069.25 PVD24581.1 - 2.6e-56 190.9 0.3 2.6e-56 190.9 0.3 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24581.1 - 1.4e-43 149.1 0.3 3.8e-43 147.6 0.3 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 PVD24581.1 - 3.2e-30 104.1 7.5 2.1e-23 82.3 3.0 2.6 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain Tn7_TnsC_Int PF11426.8 PVD24581.1 - 0.022 14.9 0.1 0.085 13.0 0.1 2.1 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC DUF2892 PF11127.8 PVD24582.1 - 0.17 11.9 1.6 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Yippee-Mis18 PF03226.14 PVD24584.1 - 0.013 15.7 0.1 0.038 14.2 0.1 1.8 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Kelch_1 PF01344.25 PVD24585.1 - 5.1e-38 128.4 3.4 8.9e-12 44.4 0.4 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 PVD24585.1 - 1.2e-26 92.1 3.3 4.9e-08 33.0 0.1 4.6 1 1 3 4 4 4 4 Kelch motif BACK PF07707.15 PVD24585.1 - 2e-23 82.4 0.4 3.4e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD24585.1 - 3.4e-18 65.5 7.6 1.5e-09 37.9 0.2 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD24585.1 - 4.5e-15 55.4 0.3 9.9e-06 25.5 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD24585.1 - 2.9e-12 46.0 2.6 0.00024 20.9 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 PVD24585.1 - 1.3e-09 37.8 6.9 0.00027 20.8 0.2 3.7 3 0 0 3 3 3 3 Kelch motif PRIMA1 PF16101.5 PVD24587.1 - 0.014 15.4 9.6 0.017 15.1 9.6 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD24587.1 - 0.024 14.1 3.6 0.023 14.2 3.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD24587.1 - 0.067 13.3 2.6 0.069 13.2 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Androgen_recep PF02166.16 PVD24587.1 - 0.22 10.3 2.3 0.25 10.1 2.3 1.1 1 0 0 1 1 1 0 Androgen receptor Lig_chan-Glu_bd PF10613.9 PVD24588.1 - 4.4e-34 117.1 0.0 6.6e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD24588.1 - 1.3e-30 106.2 0.0 2.7e-30 105.2 0.0 1.3 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD24588.1 - 1.2e-23 83.7 0.0 1.8e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans PF00520.31 PVD24588.1 - 0.057 12.6 2.9 0.06 12.6 1.1 1.9 2 0 0 2 2 2 0 Ion transport protein DUF805 PF05656.14 PVD24588.1 - 6.6 7.2 7.0 11 6.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF805) GRAM PF02893.20 PVD24589.1 - 4.6e-11 42.6 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 PVD24589.1 - 5.9e-08 32.6 3.9 2.7e-07 30.5 0.0 2.7 3 0 0 3 3 3 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 PVD24589.1 - 0.0006 19.3 1.4 0.0006 19.3 1.4 2.5 2 1 0 2 2 2 1 Plant protein of unknown function (DUF639) Vps36_ESCRT-II PF11605.8 PVD24589.1 - 0.00095 19.3 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Tmemb_cc2 PF10267.9 PVD24589.1 - 0.0019 17.4 3.8 0.0033 16.7 3.8 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Cortex-I_coil PF09304.10 PVD24589.1 - 0.034 14.4 5.9 0.087 13.0 5.9 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil Reticulon PF02453.17 PVD24589.1 - 0.21 11.6 1.8 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Reticulon Pex24p PF06398.11 PVD24589.1 - 2.8 6.8 13.5 0.47 9.4 8.4 2.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin NPR2 PF06218.11 PVD24590.1 - 9.4e-35 120.2 1.1 1.3e-32 113.1 1.1 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Pentapeptide PF00805.22 PVD24591.1 - 9.5e-39 130.6 27.5 7.2e-14 51.1 3.1 4.9 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PVD24591.1 - 5e-24 84.3 0.6 9.2e-11 41.8 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PVD24591.1 - 4.6e-21 74.7 0.0 3e-07 30.5 0.0 4.3 3 1 0 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 PVD24591.1 - 1.7e-19 70.0 0.0 2.9e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain KHA PF11834.8 PVD24591.1 - 5.3e-08 32.8 0.1 1.1e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB_3 PF16017.5 PVD24591.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 PVD24591.1 - 0.0092 16.2 0.0 0.023 14.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DNA_ligase_OB PF03120.16 PVD24591.1 - 0.17 11.8 0.1 14 5.6 0.1 2.9 2 1 1 3 3 3 0 NAD-dependent DNA ligase OB-fold domain Adaptin_N PF01602.20 PVD24592.1 - 1.8e-54 185.2 4.1 3.4e-34 118.3 0.1 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 PVD24592.1 - 4.9e-05 23.2 0.5 0.046 14.0 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 PVD24592.1 - 0.00033 20.8 9.1 0.011 15.8 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD24592.1 - 0.0017 18.7 0.3 0.23 11.9 0.0 3.3 2 0 0 2 2 2 1 HEAT repeats Cnd3 PF12719.7 PVD24592.1 - 0.0076 15.5 11.6 0.11 11.6 0.1 4.1 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Tti2 PF10521.9 PVD24592.1 - 1.6 8.2 8.0 0.52 9.8 0.2 3.2 4 0 0 4 4 4 0 Tti2 family SRP72 PF08492.12 PVD24593.1 - 2.1e-17 63.3 3.7 2.1e-17 63.3 3.7 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain F-box-like PF12937.7 PVD24593.1 - 2.4e-11 43.3 0.1 6.6e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 PVD24593.1 - 1.3e-10 40.5 14.6 0.041 13.9 0.1 9.2 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 PVD24593.1 - 3.8e-09 36.7 22.9 0.12 12.8 0.1 6.8 6 1 2 8 8 7 4 Leucine Rich repeats (2 copies) F-box PF00646.33 PVD24593.1 - 2.5e-07 30.4 0.2 5.8e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain TPR_14 PF13428.6 PVD24593.1 - 6.9e-07 29.6 6.2 0.22 12.4 0.1 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat LRR_8 PF13855.6 PVD24593.1 - 1.1e-06 28.3 4.5 0.13 12.1 0.0 5.7 5 1 1 6 6 6 2 Leucine rich repeat TPR_16 PF13432.6 PVD24593.1 - 2e-06 28.3 0.4 1.4 9.7 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD24593.1 - 3e-05 24.4 13.5 0.34 11.6 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PVD24593.1 - 0.0028 17.3 1.2 0.31 10.7 0.1 3.3 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) LRR_1 PF00560.33 PVD24593.1 - 0.0053 17.1 20.2 1.6 9.6 0.0 8.5 8 1 0 8 8 8 1 Leucine Rich Repeat TPR_MalT PF17874.1 PVD24593.1 - 0.0069 15.8 7.9 0.82 9.0 0.8 2.9 2 1 1 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 PVD24593.1 - 0.03 14.8 19.3 1 9.9 0.5 5.3 3 2 3 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 PVD24593.1 - 0.037 13.0 0.6 0.45 9.5 0.1 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 PVD24593.1 - 0.13 12.6 0.2 0.13 12.6 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD24593.1 - 0.26 11.0 14.1 0.076 12.7 0.9 3.8 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain H-K_ATPase_N PF09040.11 PVD24593.1 - 8 7.0 21.4 2 8.9 7.5 2.8 2 0 0 2 2 2 0 Gastric H+/K+-ATPase, N terminal domain ILEI PF15711.5 PVD24594.1 - 2e-46 156.4 0.9 2.5e-23 82.4 0.1 2.5 2 0 0 2 2 2 2 Interleukin-like EMT inducer GNT-I PF03071.15 PVD24594.1 - 9.2e-14 51.0 0.0 2.1e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 GNT-I family DUF4628 PF15429.6 PVD24595.1 - 0.054 13.2 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Corazonin PF17308.2 PVD24597.1 - 0.004 17.5 6.9 0.0044 17.4 6.9 1.2 1 0 0 1 1 1 1 Pro-corazonin Menin PF05053.13 PVD24597.1 - 0.065 11.6 6.1 0.065 11.6 6.1 1.0 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 PVD24597.1 - 0.073 13.6 10.4 0.093 13.3 10.4 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.8 PVD24597.1 - 1.3 9.0 11.3 1.6 8.7 11.3 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Orf78 PF06024.12 PVD24597.1 - 5.5 7.4 8.8 7.1 7.0 8.8 1.2 1 0 0 1 1 1 0 Orf78 (ac78) 7tm_3 PF00003.22 PVD24598.1 - 2.8e-61 207.3 25.0 2.8e-61 207.3 25.0 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD24598.1 - 8.5e-57 192.8 0.2 1.4e-56 192.1 0.0 1.4 2 0 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD24598.1 - 9.3e-07 28.8 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein NCD3G PF07562.14 PVD24598.1 - 0.00063 19.7 16.3 0.0014 18.5 9.9 2.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR CAAD PF14159.6 PVD24598.1 - 0.13 12.1 0.5 0.38 10.6 0.5 1.7 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ANF_receptor PF01094.28 PVD24599.1 - 5.9e-20 71.7 0.0 7.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region WD40 PF00400.32 PVD24600.1 - 9.8e-22 76.9 23.1 0.0012 19.7 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD24600.1 - 9.2e-08 32.3 5.6 0.13 12.6 0.0 4.2 2 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD24600.1 - 0.011 14.7 1.9 0.9 8.4 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cadherin PF00028.17 PVD24602.1 - 1.5e-170 554.2 31.1 3.3e-23 81.9 0.1 9.7 9 0 0 9 9 9 9 Cadherin domain 7tm_2 PF00002.24 PVD24602.1 - 3.5e-41 141.1 26.0 5.3e-41 140.5 26.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.24 PVD24602.1 - 3e-36 124.8 2.8 3.4e-20 72.9 0.0 3.5 4 0 0 4 4 4 2 Laminin G domain Laminin_G_1 PF00054.23 PVD24602.1 - 2.5e-22 79.5 0.0 7.5e-16 58.5 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain GAIN PF16489.5 PVD24602.1 - 8.4e-22 77.6 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Cadherin_2 PF08266.12 PVD24602.1 - 1e-10 41.3 0.1 0.61 10.0 0.0 7.9 8 0 0 8 8 8 2 Cadherin-like Laminin_EGF PF00053.24 PVD24602.1 - 1e-09 38.4 13.4 1e-09 38.4 13.4 8.6 6 2 2 8 8 7 2 Laminin EGF domain Cadherin_3 PF16184.5 PVD24602.1 - 7.1e-09 35.6 29.9 0.19 11.7 0.3 8.9 10 0 0 10 10 10 5 Cadherin-like EGF PF00008.27 PVD24602.1 - 2.6e-08 34.0 90.2 8.3e-05 22.8 9.7 8.3 7 1 0 7 7 5 5 EGF-like domain GPS PF01825.21 PVD24602.1 - 7.2e-05 23.2 4.9 7.2e-05 23.2 4.9 3.3 3 0 0 3 3 1 1 GPCR proteolysis site, GPS, motif RET_CLD1 PF17756.1 PVD24602.1 - 0.00059 20.1 0.0 0.24 11.7 0.0 4.3 4 0 0 4 4 4 1 RET Cadherin like domain 1 hEGF PF12661.7 PVD24602.1 - 0.0025 18.4 5.8 0.0025 18.4 5.8 7.9 8 0 0 8 8 8 3 Human growth factor-like EGF Peptidase_M16 PF00675.20 PVD24603.1 - 2.2e-55 186.7 0.0 3.5e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PVD24603.1 - 1.1e-36 126.5 0.0 1.7e-34 119.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain DEAD PF00270.29 PVD24604.1 - 1.7e-36 125.6 0.1 5.4e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD24604.1 - 3.1e-23 82.2 1.6 2.3e-22 79.5 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD24604.1 - 1.8e-07 31.3 0.0 8.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit B-block_TFIIIC PF04182.12 PVD24604.1 - 7.9e-05 22.7 0.1 0.01 16.0 0.0 3.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC AAA_19 PF13245.6 PVD24604.1 - 0.002 18.5 0.1 0.0081 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD24604.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 PVD24604.1 - 0.018 14.4 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DnaJ_CXXCXGXG PF00684.19 PVD24605.1 - 0.0075 16.6 24.3 0.0075 16.6 24.3 3.9 3 1 1 4 4 4 2 DnaJ central domain Anti-TRAP PF15777.5 PVD24605.1 - 0.022 14.7 2.3 0.022 14.7 2.3 3.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Elf1 PF05129.13 PVD24605.1 - 0.1 12.7 19.4 0.93 9.6 5.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like G-alpha PF00503.20 PVD24606.1 - 9.1e-124 413.2 2.7 1.1e-123 413.0 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD24606.1 - 7.7e-18 64.5 0.4 7.8e-13 48.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD24606.1 - 1.3e-05 24.7 3.4 0.0029 17.0 1.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD24606.1 - 0.00028 21.1 0.2 0.95 9.7 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 PVD24606.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 PVD24606.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 PVD24606.1 - 0.095 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 PVD24606.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 PVD24606.1 - 0.11 12.0 1.9 5.3 6.6 0.7 2.4 2 0 0 2 2 2 0 Ras family RabGAP-TBC PF00566.18 PVD24607.1 - 2.2e-29 102.7 2.5 1.4e-26 93.5 0.7 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PBP1_TM PF14812.6 PVD24607.1 - 2.7 8.4 7.3 1.2 9.6 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal G6PD_C PF02781.16 PVD24608.1 - 3.6e-115 384.1 0.0 4.9e-115 383.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PVD24608.1 - 9.1e-60 202.3 0.0 1.7e-59 201.4 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain LEM PF03020.15 PVD24609.1 - 1.4e-15 56.6 0.0 2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 LEM domain GlcNAc_2-epim PF07221.11 PVD24610.1 - 1.2e-40 139.8 0.2 1.6e-40 139.4 0.2 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 PVD24610.1 - 0.016 14.7 1.2 0.039 13.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 PX PF00787.24 PVD24611.1 - 8.7e-19 67.6 0.0 2.8e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 PVD24611.1 - 7.2e-07 28.8 0.0 5.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD24611.1 - 3.6e-06 26.5 0.0 9.3e-05 21.9 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain WH2 PF02205.20 PVD24611.1 - 7.5e-06 25.6 1.7 1.4e-05 24.7 1.0 1.9 2 0 0 2 2 2 1 WH2 motif DUF1682 PF07946.14 PVD24611.1 - 0.053 12.7 1.1 0.084 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAP PF07174.11 PVD24611.1 - 9.3 5.6 30.8 15 5.0 30.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Globin PF00042.22 PVD24613.1 - 5.3e-19 68.8 0.0 7.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Globin MlaC PF05494.12 PVD24613.1 - 0.08 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 MlaC protein Guanylate_kin PF00625.21 PVD24614.1 - 1.2e-11 44.7 0.0 2.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase WW PF00397.26 PVD24614.1 - 0.00072 19.6 0.0 0.0049 16.9 0.0 2.2 2 0 0 2 2 2 1 WW domain PDZ PF00595.24 PVD24614.1 - 0.015 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 PVD24615.1 - 0.0033 17.7 0.0 0.0044 17.3 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD24616.1 - 5.1e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD24616.1 - 0.011 15.5 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 PVD24617.1 - 1.1e-49 166.7 5.5 7.4e-17 61.5 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 PVD24617.1 - 1.6e-33 114.3 1.3 2.4e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PVD24617.1 - 1.6e-14 54.0 0.1 0.00044 20.5 0.3 3.3 2 1 1 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 PVD24617.1 - 1.9e-05 24.5 0.2 2.1 8.4 0.0 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 PVD24617.1 - 0.01 16.2 0.1 36 4.8 0.0 3.4 3 0 0 3 3 3 0 PDZ domain GTP_EFTU_D2 PF03144.25 PVD24617.1 - 0.055 13.9 0.3 7.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 2 DUF4200 PF13863.6 PVD24618.1 - 7.1e-35 120.0 18.7 7.1e-35 120.0 18.7 5.7 4 1 2 6 6 6 1 Domain of unknown function (DUF4200) Shisa PF13908.6 PVD24619.1 - 1.8e-07 31.6 0.3 2.6e-07 31.1 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 PVD24619.1 - 0.00058 20.5 1.2 0.0015 19.2 1.2 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 MLANA PF14991.6 PVD24619.1 - 0.0013 19.0 0.9 0.0013 19.0 0.9 2.4 3 0 0 3 3 2 1 Protein melan-A Prominin PF05478.11 PVD24619.1 - 0.01 13.8 3.0 0.014 13.3 3.0 1.1 1 0 0 1 1 1 0 Prominin Mucin PF01456.17 PVD24619.1 - 0.01 15.8 1.3 0.019 15.0 1.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein EphA2_TM PF14575.6 PVD24619.1 - 0.021 15.7 0.2 0.059 14.2 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 PVD24619.1 - 0.032 14.2 0.2 0.07 13.1 0.2 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Orthoreo_P10 PF07204.11 PVD24619.1 - 0.067 13.1 1.4 0.098 12.6 0.3 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 TraL PF07178.11 PVD24619.1 - 0.071 13.6 0.3 0.15 12.5 0.3 1.5 1 0 0 1 1 1 0 TraL protein DUF2371 PF10177.9 PVD24619.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Mid2 PF04478.12 PVD24619.1 - 0.099 12.5 1.2 0.17 11.7 1.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMIE PF16038.5 PVD24619.1 - 0.64 9.9 6.8 1.7 8.5 6.8 1.6 1 0 0 1 1 1 0 TMIE protein Adeno_E3_CR2 PF02439.15 PVD24619.1 - 3.7 7.4 16.2 0.4 10.5 9.9 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 zf-RING_2 PF13639.6 PVD24620.1 - 0.00072 19.8 1.9 0.0018 18.6 1.9 1.6 1 0 0 1 1 1 1 Ring finger domain DUF1644 PF07800.12 PVD24620.1 - 0.00093 19.3 1.7 0.0018 18.3 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-C3HC4_4 PF15227.6 PVD24620.1 - 0.026 14.7 3.0 0.049 13.8 3.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD24620.1 - 0.034 14.0 3.1 0.071 13.0 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD24620.1 - 0.048 13.7 0.7 0.11 12.6 0.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD24620.1 - 0.056 13.3 2.0 0.11 12.4 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PVD24620.1 - 0.32 10.8 2.9 0.9 9.4 2.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 PVD24620.1 - 0.46 10.4 3.2 1.1 9.2 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AARP2CN PF08142.12 PVD24621.1 - 0.046 13.8 6.0 2.2 8.4 0.0 4.2 4 0 0 4 4 4 0 AARP2CN (NUC121) domain TMEM52 PF14979.6 PVD24622.1 - 0.00069 19.6 0.8 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 Transmembrane 52 SieB PF14163.6 PVD24622.1 - 0.0081 15.7 0.7 0.19 11.2 0.1 2.2 2 0 0 2 2 2 1 Super-infection exclusion protein B HemY_N PF07219.13 PVD24622.1 - 0.01 16.0 0.5 0.018 15.2 0.5 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Orf78 PF06024.12 PVD24622.1 - 0.02 15.2 0.4 0.04 14.2 0.4 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 PVD24622.1 - 0.036 13.6 1.3 0.08 12.5 1.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Aerolysin PF01117.20 PVD24622.1 - 0.052 12.8 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 Aerolysin toxin 7TM_GPCR_Srw PF10324.9 PVD24622.1 - 0.063 12.6 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw EphA2_TM PF14575.6 PVD24622.1 - 0.16 12.9 0.0 0.42 11.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nrf1_DNA-bind PF10491.9 PVD24623.1 - 1.7e-14 54.1 0.0 3.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2841 PF11001.8 PVD24623.1 - 0.0018 18.3 0.2 0.0056 16.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) zf-C2H2 PF00096.26 PVD24626.1 - 0.079 13.5 3.0 0.22 12.0 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type RhoGAP PF00620.27 PVD24627.1 - 1e-43 148.8 0.2 3.5e-43 147.1 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 PVD24627.1 - 4e-14 52.6 2.7 4e-14 52.6 2.7 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 PVD24627.1 - 9.6e-14 50.7 0.0 2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD24627.1 - 1.4e-08 34.3 0.0 3.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD24627.1 - 1.7e-08 34.1 0.3 4.6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SopA PF13981.6 PVD24627.1 - 1 9.8 3.5 6.3 7.2 0.3 2.4 2 0 0 2 2 2 0 SopA-like central domain DUF4486 PF14858.6 PVD24630.1 - 1.3e-210 700.5 0.7 3.7e-143 477.9 1.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4486) TPR_2 PF07719.17 PVD24630.1 - 0.069 13.3 1.8 0.56 10.5 1.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD24630.1 - 0.12 12.7 2.4 88 3.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GTSE1_N PF15259.6 PVD24631.1 - 7.1e-17 61.9 0.1 7.1e-17 61.9 0.1 2.8 1 1 1 2 2 2 1 G-2 and S-phase expressed 1 CTK3 PF12243.8 PVD24632.1 - 0.004 17.1 5.7 0.39 10.7 0.4 2.5 1 1 1 2 2 2 2 CTD kinase subunit gamma CTK3 Sld5 PF05916.11 PVD24632.1 - 0.037 14.5 5.9 0.068 13.6 4.5 2.2 1 1 1 2 2 2 0 GINS complex protein 7tm_3 PF00003.22 PVD24637.1 - 2.5e-28 99.4 23.8 4.1e-28 98.7 23.8 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD24637.1 - 2.1e-13 50.1 0.0 4.2e-07 29.4 0.0 3.6 3 1 1 4 4 4 3 Receptor family ligand binding region TRAP-delta PF05404.12 PVD24640.1 - 6e-61 204.7 0.0 7.6e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) LRR_6 PF13516.6 PVD24642.1 - 7.8e-08 31.8 4.2 0.41 10.8 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat SKI PF01202.22 PVD24643.1 - 2.4e-33 115.5 0.1 1.2e-32 113.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Thr_synth_N PF14821.6 PVD24643.1 - 1e-12 48.0 0.0 3.8e-11 43.0 0.0 2.6 2 0 0 2 2 2 1 Threonine synthase N terminus AAA_18 PF13238.6 PVD24643.1 - 1.9e-06 28.5 0.0 4.9e-06 27.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 PVD24643.1 - 4.5e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PVD24643.1 - 0.00046 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 PVD24643.1 - 0.01 16.3 0.0 0.23 11.9 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 PVD24643.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 PVD24643.1 - 0.011 15.6 0.0 5 6.9 0.0 2.8 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_33 PF13671.6 PVD24643.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 PVD24643.1 - 0.035 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 PVD24643.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 1 1 1 2 2 2 0 Cytidylate kinase-like family AAA_22 PF13401.6 PVD24643.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4539 PF15072.6 PVD24644.1 - 5e-19 68.1 0.0 1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) CD20 PF04103.15 PVD24646.1 - 1.2e-11 44.9 9.2 2e-11 44.2 9.2 1.3 1 0 0 1 1 1 1 CD20-like family MJ1316 PF04457.12 PVD24647.1 - 3.7e-24 85.3 0.2 6.6e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain TAA-Trp-ring PF15401.6 PVD24647.1 - 0.074 13.5 7.8 0.14 12.7 7.8 1.4 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin AKAP7_NLS PF10469.9 PVD24648.1 - 3.5e-35 121.8 0.0 1.7e-34 119.6 0.0 1.7 1 1 1 2 2 2 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 PVD24648.1 - 3.8e-08 33.4 0.3 5.2e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PVD24648.1 - 0.012 15.7 0.5 0.14 12.4 0.0 2.3 2 1 0 2 2 2 0 LigT like Phosphoesterase AKAP7_NLS PF10469.9 PVD24649.1 - 5.6e-41 140.7 0.0 1.2e-40 139.6 0.0 1.6 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 PVD24649.1 - 1.8e-26 92.6 0.6 5.7e-26 91.1 0.6 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain RWD PF05773.22 PVD24649.1 - 7.8e-08 32.6 0.0 2.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 RWD domain 2_5_RNA_ligase2 PF13563.6 PVD24649.1 - 3.5e-06 27.0 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PVD24649.1 - 0.025 14.7 0.0 0.16 12.2 0.0 2.1 1 1 1 2 2 2 0 LigT like Phosphoesterase DUF5327 PF17261.2 PVD24649.1 - 0.99 10.2 6.0 1.3 9.8 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Y_phosphatase PF00102.27 PVD24650.1 - 4.1e-51 173.8 1.2 6.8e-51 173.1 1.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4328 PF14219.6 PVD24650.1 - 0.015 14.8 0.7 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) EphA2_TM PF14575.6 PVD24650.1 - 0.05 14.5 0.3 0.17 12.8 0.3 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 PVD24650.1 - 0.28 11.6 3.2 0.74 10.3 0.8 2.6 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein CcmD PF04995.14 PVD24650.1 - 0.89 9.7 3.4 1.7 8.8 3.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Stevor PF17410.2 PVD24650.1 - 3.4 7.1 5.2 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4690 PF15756.5 PVD24650.1 - 7.7 7.2 6.8 0.68 10.6 0.2 2.4 2 1 1 3 3 3 0 Small Novel Rich in Cartilage Y_phosphatase PF00102.27 PVD24651.1 - 3.4e-51 174.1 0.3 5.6e-51 173.4 0.3 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Insulin_TMD PF17870.1 PVD24651.1 - 0.00012 22.1 0.5 0.00021 21.3 0.5 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment GAPT PF11770.8 PVD24651.1 - 0.00013 21.9 0.8 0.019 14.8 0.2 4.2 3 2 1 4 4 4 1 GRB2-binding adapter (GAPT) Stevor PF17410.2 PVD24651.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TraL PF07178.11 PVD24652.1 - 0.025 15.0 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 TraL protein PHF5 PF03660.14 PVD24653.1 - 1.4 9.2 15.5 2.7 8.3 5.8 2.3 1 1 1 2 2 2 0 PHF5-like protein SKG6 PF08693.10 PVD24654.1 - 0.053 12.9 0.7 0.095 12.1 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TraL PF07178.11 PVD24654.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 TraL protein Y_phosphatase PF00102.27 PVD24655.1 - 8.9e-37 126.9 0.1 2.2e-36 125.6 0.1 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Insulin_TMD PF17870.1 PVD24655.1 - 0.00027 20.9 0.3 0.00055 19.9 0.3 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Stevor PF17410.2 PVD24655.1 - 0.013 15.0 1.2 0.016 14.8 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF2681 PF10883.8 PVD24655.1 - 0.024 15.0 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Syndecan PF01034.20 PVD24655.1 - 0.11 12.4 0.5 0.23 11.4 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain GAPT PF11770.8 PVD24655.1 - 0.49 10.3 5.8 0.93 9.3 0.2 2.7 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) PTP_tm PF18861.1 PVD24655.1 - 1.2 9.2 4.2 0.22 11.5 0.5 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DSL PF01414.19 PVD24655.1 - 2.4 8.5 34.1 1.9 8.8 9.2 3.1 2 1 1 3 3 3 0 Delta serrate ligand Y_phosphatase PF00102.27 PVD24656.1 - 1.9e-36 125.8 0.4 2.7e-36 125.3 0.4 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF983 PF06170.12 PVD24657.1 - 0.46 10.9 3.0 0.66 10.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF347 PF03988.12 PVD24658.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TRAF6_Z2 PF18048.1 PVD24658.1 - 0.42 10.7 7.4 2.7 8.2 1.4 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 PHF5 PF03660.14 PVD24658.1 - 1.2 9.3 19.6 13 6.1 12.7 2.4 1 1 1 2 2 2 0 PHF5-like protein VWA PF00092.28 PVD24659.1 - 8.2e-10 39.2 0.0 1.3e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD24659.1 - 3.2e-06 27.7 0.0 6.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TraL PF07178.11 PVD24660.1 - 0.082 13.4 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 TraL protein Y_phosphatase PF00102.27 PVD24661.1 - 1.3e-49 168.9 0.2 1.9e-49 168.4 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EphA2_TM PF14575.6 PVD24661.1 - 0.0041 18.0 0.0 0.47 11.4 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.8 PVD24661.1 - 0.0054 16.9 0.6 0.018 15.2 0.1 2.0 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Colicin_V PF02674.16 PVD24661.1 - 0.016 15.2 1.0 0.49 10.3 0.2 2.2 2 0 0 2 2 2 0 Colicin V production protein DUF4328 PF14219.6 PVD24661.1 - 0.031 13.8 1.9 0.16 11.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) Yip1 PF04893.17 PVD24661.1 - 0.051 13.3 0.5 1 9.0 0.1 2.1 2 0 0 2 2 2 0 Yip1 domain ECSCR PF15820.5 PVD24661.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator CPP1-like PF11833.8 PVD24661.1 - 0.26 10.9 0.7 10 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PTP_tm PF18861.1 PVD24661.1 - 0.88 9.5 2.5 22 5.0 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2530 PF10745.9 PVD24661.1 - 1.1 9.5 6.0 21 5.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Syndecan PF01034.20 PVD24661.1 - 8.8 6.3 8.0 1.9 8.4 3.0 2.2 2 0 0 2 2 2 0 Syndecan domain Y_phosphatase PF00102.27 PVD24664.1 - 5.8e-51 173.3 0.1 9.8e-51 172.6 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MAP17 PF15807.5 PVD24664.1 - 0.0042 17.3 0.5 0.0042 17.3 0.5 2.0 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 S1FA PF04689.13 PVD24664.1 - 0.034 14.3 0.2 0.077 13.2 0.2 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA OAD_gamma PF04277.13 PVD24664.1 - 8.6 7.0 8.0 1.7 9.3 3.6 2.2 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Y_phosphatase PF00102.27 PVD24665.1 - 9.1e-49 166.1 0.8 1.4e-48 165.5 0.2 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 PVD24665.1 - 0.00012 22.2 0.0 0.00035 20.7 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain EphA2_TM PF14575.6 PVD24665.1 - 0.00013 22.8 0.0 0.071 14.0 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD24665.1 - 0.00077 19.4 0.0 0.047 13.6 0.0 2.8 3 0 0 3 3 3 1 TMEM154 protein family Protocadherin PF08374.11 PVD24665.1 - 0.0032 17.5 0.1 0.0094 15.9 0.0 1.8 2 0 0 2 2 2 1 Protocadherin RIFIN PF02009.16 PVD24665.1 - 0.0058 16.6 3.6 0.083 12.8 0.0 2.5 2 0 0 2 2 2 1 Rifin DAP10 PF07213.11 PVD24665.1 - 0.0078 16.1 0.9 0.3 11.1 0.2 2.6 2 0 0 2 2 2 1 DAP10 membrane protein Syndecan PF01034.20 PVD24665.1 - 0.032 14.1 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Syndecan domain DUF2561 PF10812.8 PVD24665.1 - 0.1 12.6 0.7 0.2 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Miga PF10265.9 PVD24665.1 - 0.19 10.6 3.3 0.23 10.4 2.0 1.5 1 1 1 2 2 2 0 Mitoguardin Insulin_TMD PF17870.1 PVD24665.1 - 1.9 8.6 3.6 1.1 9.4 0.6 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment HTH_Tnp_Tc5 PF03221.16 PVD24666.1 - 0.00083 19.3 0.3 0.0015 18.5 0.3 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain F5_F8_type_C PF00754.25 PVD24667.1 - 8.5e-06 25.9 0.0 0.2 11.8 0.1 2.5 2 0 0 2 2 2 2 F5/8 type C domain Y_phosphatase PF00102.27 PVD24668.1 - 3.2e-64 216.7 7.8 4.3e-51 173.7 0.2 3.4 2 1 1 3 3 3 3 Protein-tyrosine phosphatase RVT_1 PF00078.27 PVD24668.1 - 1.7e-21 76.8 0.1 3.2e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EphA2_TM PF14575.6 PVD24668.1 - 1.9e-07 31.8 1.1 0.023 15.6 0.0 4.1 4 0 0 4 4 4 2 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD24668.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 4.1 5 0 0 5 5 4 1 Insulin receptor trans-membrane segment DUF4381 PF14316.6 PVD24668.1 - 0.0022 18.3 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DUF202 PF02656.15 PVD24668.1 - 0.013 16.0 9.0 5.1 7.6 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 PVD24668.1 - 0.054 12.3 2.2 5.8 5.5 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1043 PF06295.12 PVD24668.1 - 0.1 12.6 0.1 0.45 10.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Gram_pos_anchor PF00746.21 PVD24668.1 - 0.18 11.8 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Protocadherin PF08374.11 PVD24668.1 - 0.21 11.5 8.1 1.4 8.9 0.0 3.0 2 1 0 3 3 3 0 Protocadherin CcmD PF04995.14 PVD24668.1 - 0.73 10.0 7.5 2.9 8.0 1.6 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Syndecan PF01034.20 PVD24668.1 - 0.93 9.5 10.6 2.1 8.3 0.1 3.3 3 0 0 3 3 2 0 Syndecan domain Neur_chan_memb PF02932.16 PVD24668.1 - 1.3 9.0 8.8 0.24 11.4 1.4 2.6 3 0 0 3 3 2 0 Neurotransmitter-gated ion-channel transmembrane region TMEM154 PF15102.6 PVD24668.1 - 1.7 8.5 6.9 1.3 8.9 0.0 3.4 3 0 0 3 3 3 0 TMEM154 protein family DUF2367 PF10164.9 PVD24668.1 - 5.4 7.6 12.3 0.076 13.5 0.5 3.3 2 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2367) DUF2367 PF10164.9 PVD24669.1 - 0.065 13.7 0.3 0.15 12.6 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ribosomal_L29 PF00831.23 PVD24669.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein DUF2613 PF11021.8 PVD24669.1 - 8.6 6.6 6.7 32 4.7 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2367 PF10164.9 PVD24670.1 - 0.059 13.9 0.1 0.13 12.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Tail_VII PF17091.5 PVD24670.1 - 5.6 6.9 5.4 8.7 6.3 4.8 1.6 1 1 0 1 1 1 0 Inovirus G7P protein S1FA PF04689.13 PVD24672.1 - 0.018 15.2 0.2 0.031 14.4 0.2 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA OAD_gamma PF04277.13 PVD24672.1 - 0.041 14.5 0.2 0.086 13.4 0.0 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain F5_F8_type_C PF00754.25 PVD24672.1 - 0.056 13.6 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain MAP17 PF15807.5 PVD24672.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MH2 PF03166.14 PVD24674.1 - 1.1e-19 71.4 0.0 2.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 MH2 domain RNase_H PF00075.24 PVD24675.1 - 1.2e-12 48.2 0.1 6.7e-12 45.8 0.0 2.1 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 PVD24675.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Yeast_MT PF11403.8 PVD24677.1 - 0.37 11.4 11.2 0.25 11.9 8.9 1.9 1 1 0 1 1 1 0 Yeast metallothionein GRDP-like PF07173.12 PVD24678.1 - 6.6e-48 163.0 5.3 5.8e-40 137.2 2.1 2.3 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like Sugar_tr PF00083.24 PVD24679.1 - 5.6e-110 368.3 21.6 3e-82 276.9 9.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD24679.1 - 6.8e-28 97.6 22.5 4.3e-26 91.7 13.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PVD24679.1 - 0.004 15.6 1.2 0.0088 14.5 1.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PSI_integrin PF17205.3 PVD24679.1 - 0.0078 15.9 3.2 0.022 14.5 3.2 1.8 1 0 0 1 1 1 1 Integrin plexin domain B277 PF17623.2 PVD24679.1 - 3.2 6.8 7.0 1.2 8.2 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function Hydrolase PF00702.26 PVD24680.1 - 2e-14 54.4 0.0 2.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD24680.1 - 1e-13 52.1 0.0 1.8e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 PVD24680.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 PVD24680.1 - 0.039 14.1 0.0 9 6.3 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Laps PF10169.9 PVD24681.1 - 5.8e-29 101.2 21.8 7.3e-29 100.9 21.8 1.1 1 0 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 PVD24681.1 - 0.0008 19.6 5.2 0.0008 19.6 5.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Actin PF00022.19 PVD24682.1 - 1.9e-34 119.0 0.1 1.7e-19 69.7 0.0 3.0 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 PVD24682.1 - 3e-11 43.1 0.9 9.3e-05 21.8 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 PVD24682.1 - 0.00033 19.6 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF3682 PF12446.8 PVD24682.1 - 0.1 13.1 4.6 0.19 12.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Usp PF00582.26 PVD24683.1 - 9.5e-18 65.1 0.2 1.2e-17 64.7 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family Dot_icm_IcmQ PF09475.10 PVD24683.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Aminoglyc_resit PF10706.9 PVD24684.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Amidohydro_1 PF01979.20 PVD24685.1 - 1.5e-07 31.1 0.1 8.3e-07 28.6 0.0 2.0 1 1 2 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.11 PVD24685.1 - 4.5e-06 26.4 0.0 6.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF3338 PF11819.8 PVD24686.1 - 5.6e-34 117.0 4.0 5.6e-34 117.0 4.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.18 PVD24686.1 - 7.9e-20 71.4 3.2 1.5e-19 70.5 0.0 2.4 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 PVD24686.1 - 5.6e-17 61.9 0.2 1.4e-16 60.6 0.2 1.8 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 PVD24686.1 - 1.6e-07 31.1 0.1 6.8e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 FERM N-terminal domain BCAS2 PF05700.11 PVD24686.1 - 0.031 14.0 10.1 0.32 10.7 0.4 2.3 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SDP_N PF12278.8 PVD24687.1 - 0.58 10.3 4.5 0.12 12.5 0.8 1.8 2 0 0 2 2 2 0 Sex determination protein N terminal DUF3338 PF11819.8 PVD24689.1 - 1.4e-33 115.7 4.0 1.4e-33 115.7 4.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 PVD24689.1 - 2.9e-25 88.5 0.1 6.6e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD24689.1 - 1.3e-11 44.9 8.4 2.7e-07 31.0 0.1 4.4 3 1 1 4 4 4 2 FERM central domain FERM_N PF09379.10 PVD24689.1 - 2.9e-10 39.9 0.3 7.1e-10 38.7 0.3 1.6 1 0 0 1 1 1 1 FERM N-terminal domain BCAS2 PF05700.11 PVD24689.1 - 0.13 11.9 11.1 0.59 9.8 0.7 2.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Lyase_aromatic PF00221.19 PVD24690.1 - 2.1e-136 455.3 2.9 4.8e-72 243.1 0.7 3.0 1 1 2 3 3 3 3 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 PVD24690.1 - 1.3e-08 34.9 0.0 4.2e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins HECT PF00632.25 PVD24691.1 - 8.9e-93 311.1 1.2 1.4e-92 310.5 1.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 PVD24691.1 - 1.5e-84 284.1 0.0 9.7e-70 235.4 0.0 6.4 7 1 1 8 8 8 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 PVD24691.1 - 2.4e-25 89.7 9.9 2.9e-14 53.3 4.0 5.9 5 1 1 6 6 6 2 Domain of Unknown Function (DUF908) UBM PF14377.6 PVD24691.1 - 5.6e-20 70.1 10.0 2.5e-10 39.4 1.4 3.1 2 0 0 2 2 2 2 Ubiquitin binding region WWE PF02825.20 PVD24691.1 - 2.9e-11 43.8 0.4 1e-10 42.1 0.4 2.0 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 PVD24691.1 - 3.2e-09 36.5 0.0 1.1e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain LIN37 PF15306.6 PVD24692.1 - 4.6e-42 143.9 0.8 4.6e-42 143.9 0.8 2.5 2 0 0 2 2 2 1 LIN37 zf-C2H2 PF00096.26 PVD24692.1 - 6.8e-09 35.7 32.4 0.0014 18.9 4.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD24692.1 - 8.7e-06 26.2 37.9 0.0013 19.3 0.5 5.1 6 0 0 6 6 4 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD24692.1 - 0.00038 21.1 3.1 0.0063 17.2 0.3 3.1 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 PVD24692.1 - 0.006 17.2 3.6 0.99 10.1 0.0 3.4 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 PVD24692.1 - 0.011 16.1 0.3 0.011 16.1 0.3 6.2 8 0 0 8 8 7 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD24692.1 - 0.02 15.1 18.2 1.7 9.0 0.4 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 PVD24692.1 - 0.06 14.0 0.5 0.06 14.0 0.5 2.5 3 0 0 3 3 3 0 TRAF-type zinc finger IBR PF01485.21 PVD24692.1 - 0.48 10.7 4.6 6.1 7.2 0.2 3.5 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf_Hakai PF18408.1 PVD24692.1 - 0.81 9.4 12.3 8.3 6.2 0.6 3.6 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain GAGA PF09237.11 PVD24692.1 - 1.6 8.6 4.0 19 5.2 0.1 3.7 4 0 0 4 4 4 0 GAGA factor zf-BED PF02892.15 PVD24692.1 - 4.5 7.4 8.9 17 5.6 0.2 3.5 3 0 0 3 3 3 0 BED zinc finger RIBIOP_C PF04950.12 PVD24693.1 - 3.2e-119 397.7 0.0 6.2e-119 396.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PVD24693.1 - 9.1e-18 64.1 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain NUSAP PF16006.5 PVD24693.1 - 5.6 6.6 11.6 8.9 6.0 11.6 1.3 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein DUF2087 PF09860.9 PVD24695.1 - 0.11 12.7 1.3 0.2 11.8 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) tRNA_edit PF04073.15 PVD24699.1 - 1.5e-22 80.0 0.0 5.4e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 Aminoacyl-tRNA editing domain Alpha_L_fucos PF01120.17 PVD24700.1 - 1.8e-105 353.3 13.4 2.2e-104 349.7 13.4 2.0 1 1 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PVD24700.1 - 9.8e-16 58.1 0.3 1.9e-15 57.2 0.3 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 PVD24700.1 - 0.021 14.9 1.3 0.13 12.3 0.8 2.5 2 1 1 3 3 3 0 Lactococcus bacteriophage putative transcription regulator Chordopox_G3 PF06129.12 PVD24701.1 - 0.12 13.1 0.0 0.14 12.9 0.0 1.0 1 0 0 1 1 1 0 Chordopoxvirus G3 protein CHB_HEX PF03173.13 PVD24702.1 - 4.2e-07 29.8 0.0 5.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Putative carbohydrate binding domain Glyco_hydro_20 PF00728.22 PVD24702.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Det1 PF09737.9 PVD24702.1 - 0.16 11.0 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 ANF_receptor PF01094.28 PVD24703.1 - 3e-21 75.9 0.0 3.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD24703.1 - 0.00017 21.4 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Guanylate_cyc PF00211.20 PVD24705.1 - 3.7e-68 228.8 0.1 3.2e-66 222.5 0.1 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 PVD24705.1 - 3.6e-54 184.2 0.0 5.3e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD24705.1 - 9.8e-23 80.7 0.0 2.5e-18 66.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD24705.1 - 8.1e-19 68.0 0.1 2.3e-17 63.2 0.0 2.7 2 1 1 3 3 3 1 Protein kinase domain HNOBA PF07701.14 PVD24705.1 - 7.7e-05 22.2 0.6 0.00014 21.4 0.6 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 PVD24705.1 - 0.013 15.2 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Laminin_EGF PF00053.24 PVD24706.1 - 0.0019 18.3 18.1 0.0019 18.3 18.1 18.7 7 6 11 18 18 18 7 Laminin EGF domain WH2 PF02205.20 PVD24707.1 - 1.3e-09 37.6 0.9 2.7e-09 36.6 0.9 1.6 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 PVD24707.1 - 3.6e-06 26.7 10.4 5.3e-06 26.1 10.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 PVD24707.1 - 2.3e-05 23.9 0.0 0.023 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24707.1 - 0.044 13.1 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Mito_fiss_reg PF05308.11 PVD24707.1 - 0.52 10.4 7.1 0.82 9.7 7.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DEC-1_N PF04625.13 PVD24707.1 - 0.91 8.5 9.5 1.6 7.6 9.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Shisa PF13908.6 PVD24707.1 - 1.9 8.7 4.3 2.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PRIMA1 PF16101.5 PVD24707.1 - 3.3 7.8 17.2 7.7 6.6 12.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Usp PF00582.26 PVD24708.1 - 2e-25 90.0 0.0 2.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Beta-Casp PF10996.8 PVD24708.1 - 0.04 14.2 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Beta-Casp domain 7tm_1 PF00001.21 PVD24709.1 - 4.2e-10 39.4 24.4 4.6e-07 29.4 10.5 3.0 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD24709.1 - 0.0012 18.3 11.0 0.0012 18.3 11.0 2.9 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srw AIG1 PF04548.16 PVD24709.1 - 0.0029 17.0 5.5 4.9 6.4 0.0 3.9 4 0 0 4 4 4 3 AIG1 family MMU163 PF17119.5 PVD24709.1 - 0.065 12.4 0.4 0.16 11.1 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Plant_vir_prot PF01307.17 PVD24709.1 - 0.085 13.1 0.3 1.7 8.9 0.0 3.1 3 1 0 3 3 3 0 Plant viral movement protein Srg PF02118.21 PVD24709.1 - 0.65 9.6 31.9 0.16 11.6 5.5 3.0 2 1 0 2 2 2 0 Srg family chemoreceptor O_anti_polymase PF01901.16 PVD24709.1 - 0.83 8.9 9.5 2.8 7.1 0.4 2.5 2 1 0 2 2 2 0 Putative O-antigen polymerase DUF2569 PF10754.9 PVD24709.1 - 0.95 9.9 18.7 0.049 14.1 3.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Abhydrolase_9_N PF15420.6 PVD24709.1 - 1.6 8.7 14.2 0.2 11.6 1.7 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus SecE PF00584.20 PVD24709.1 - 2.2 8.3 12.5 1.9 8.5 0.1 4.1 4 0 0 4 4 3 0 SecE/Sec61-gamma subunits of protein translocation complex DUF973 PF06157.11 PVD24709.1 - 2.4 7.1 14.7 0.35 9.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) 7tm_1 PF00001.21 PVD24710.1 - 1.2e-45 155.9 2.0 1.4e-45 155.7 2.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD24710.1 - 4.2e-06 26.6 4.5 4.9e-06 26.4 4.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD24710.1 - 0.0058 16.0 1.2 0.007 15.8 1.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD24710.1 - 0.16 11.2 2.6 0.22 10.8 2.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DSPc PF00782.20 PVD24712.1 - 1.1e-12 47.9 0.0 6.2e-12 45.5 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD24712.1 - 1.4e-06 28.1 0.2 3e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD24712.1 - 0.00056 19.9 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 PVD24712.1 - 0.0047 16.6 0.4 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RhoGAP PF00620.27 PVD24712.1 - 0.011 15.5 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 RhoGAP domain PhyH PF05721.13 PVD24713.1 - 2.8e-51 174.8 0.0 3.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 PVD24713.1 - 0.056 13.2 0.1 0.53 10.0 0.1 2.4 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_20 PF00728.22 PVD24714.1 - 1.6e-93 313.9 0.0 2.3e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 PVD24714.1 - 4.9e-31 107.6 0.0 1.2e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Putative carbohydrate binding domain DUF3695 PF12494.8 PVD24714.1 - 2.4e-30 104.3 1.1 5.5e-30 103.2 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) CHB_HEX_C PF03174.13 PVD24714.1 - 6.5e-17 61.3 0.0 1.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 PVD24714.1 - 2.9e-12 47.5 0.0 5.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 PVD24714.1 - 0.00022 21.9 0.0 0.00051 20.7 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like CIMR PF00878.18 PVD24715.1 - 0.0021 18.1 13.8 0.011 15.8 0.7 3.0 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Ephrin_rec_like PF07699.13 PVD24715.1 - 0.013 15.2 68.9 0.11 12.2 1.5 7.7 5 1 1 7 7 7 0 Putative ephrin-receptor like UPF0242 PF06785.11 PVD24715.1 - 0.04 14.0 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus P53_TAD PF08563.11 PVD24715.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 P53 transactivation motif BTG PF07742.12 PVD24716.1 - 8.2e-38 128.8 0.0 1.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 BTG family UCH PF00443.29 PVD24717.1 - 5.5e-54 183.4 0.0 8.6e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CS PF04969.16 PVD24717.1 - 1.5e-12 48.4 4.4 2.2e-08 35.0 0.8 2.9 2 0 0 2 2 2 2 CS domain UCH_1 PF13423.6 PVD24717.1 - 7.5e-12 45.5 0.0 2.1e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 PVD24717.1 - 2.8e-07 30.5 17.4 2.8e-07 30.5 17.4 3.0 3 0 0 3 3 3 1 MYND finger USP7_C2 PF14533.6 PVD24717.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal RNA_pol_Rpc4 PF05132.14 PVD24718.1 - 0.19 12.1 5.7 0.25 11.8 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 PVD24718.1 - 0.59 9.9 21.9 0.71 9.7 21.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GBP_C PF02841.14 PVD24718.1 - 0.81 9.0 28.0 1 8.7 28.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Presenilin PF01080.17 PVD24718.1 - 1.3 7.7 18.6 1.5 7.5 18.6 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 PVD24718.1 - 1.7 8.7 8.6 2.4 8.3 8.6 1.2 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 PVD24718.1 - 3 6.8 11.8 3.4 6.6 11.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 PVD24718.1 - 4.4 5.5 32.1 5.1 5.3 32.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 PVD24718.1 - 4.6 6.0 13.0 5.4 5.8 13.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ALMT PF11744.8 PVD24718.1 - 6.2 5.5 11.3 6.5 5.5 11.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FancD2 PF14631.6 PVD24718.1 - 7.3 3.8 10.9 7.7 3.8 10.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2828 PF11443.8 PVD24718.1 - 7.5 4.5 17.1 9 4.2 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2151 PF10221.9 PVD24718.1 - 8.2 4.9 12.9 9.2 4.7 12.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator MDM10 PF12519.8 PVD24718.1 - 8.7 5.1 13.7 8.8 5.1 13.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ank_5 PF13857.6 PVD24719.1 - 1.3e-25 89.1 3.3 5.5e-10 39.3 0.1 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD24719.1 - 2e-22 79.3 1.7 1.3e-12 48.0 0.1 4.1 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD24719.1 - 3.5e-21 75.6 0.4 1.5e-10 41.5 0.2 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD24719.1 - 1.4e-17 63.3 0.7 0.00021 21.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD24719.1 - 8.9e-17 59.5 0.5 7.4e-05 22.9 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ge1_WD40 PF16529.5 PVD24719.1 - 0.075 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AMP-binding PF00501.28 PVD24720.1 - 5.8e-40 137.2 0.0 5.8e-40 137.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD24720.1 - 1.5e-07 32.3 0.0 6.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tim54 PF11711.8 PVD24720.1 - 0.41 9.4 2.4 0.65 8.7 2.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SMN PF06003.12 PVD24720.1 - 9.3 5.4 7.8 15 4.8 7.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TIR PF01582.20 PVD24721.1 - 3.3e-14 53.1 0.0 6.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD24721.1 - 7.2e-10 39.5 0.0 3.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 TIR domain LRR_8 PF13855.6 PVD24721.1 - 1.7e-06 27.7 4.4 1.8e-05 24.4 0.2 3.1 3 1 0 3 3 3 1 Leucine rich repeat YqzE PF14038.6 PVD24721.1 - 0.0074 16.3 4.7 1.7 8.7 1.0 2.5 2 0 0 2 2 2 2 YqzE-like protein LRR_4 PF12799.7 PVD24721.1 - 0.0092 16.4 4.0 0.51 10.8 0.6 3.8 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 PVD24721.1 - 0.0097 16.5 1.2 0.025 15.3 0.1 2.4 2 0 0 2 2 2 1 Leucine Rich Repeat Pyr_redox_2 PF07992.14 PVD24722.1 - 1.7e-69 234.3 2.1 1.7e-69 234.3 2.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PVD24722.1 - 2.2e-38 130.9 0.0 6.4e-38 129.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PVD24722.1 - 4.1e-19 68.9 4.7 1e-16 61.2 1.3 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD24722.1 - 1.3e-11 44.3 0.7 3e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PVD24722.1 - 5.9e-10 39.1 6.6 1.8e-08 34.2 0.0 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 PVD24722.1 - 6.1e-08 32.1 7.0 2.8e-06 26.7 1.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PVD24722.1 - 2.3e-07 30.4 5.6 0.016 14.5 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.24 PVD24722.1 - 3.9e-07 29.5 7.7 3.2e-06 26.5 0.2 2.8 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 PVD24722.1 - 2.4e-06 27.7 3.1 0.0013 18.9 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PVD24722.1 - 1.4e-05 24.0 9.1 0.0051 15.6 0.3 3.8 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 PVD24722.1 - 2.8e-05 23.4 1.8 0.073 12.2 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 PVD24722.1 - 0.0045 16.3 4.4 0.12 11.7 0.2 3.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PVD24722.1 - 0.011 15.0 0.8 0.035 13.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 PVD24722.1 - 0.026 14.1 9.3 2.7 7.5 0.0 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PVD24722.1 - 0.094 12.0 0.3 0.35 10.1 0.0 1.7 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 PVD24722.1 - 0.48 10.0 4.8 5 6.6 0.8 2.7 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 PVD24722.1 - 0.74 9.7 4.0 0.24 11.3 0.5 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TMPIT PF07851.13 PVD24723.1 - 0.00065 19.1 13.5 0.00065 19.1 13.5 12.2 2 2 6 11 11 11 3 TMPIT-like protein zf-met PF12874.7 PVD24723.1 - 0.16 12.4 0.1 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PVD24723.1 - 0.66 11.0 2.1 4.8 8.3 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Roc PF08477.13 PVD24724.1 - 9.2e-15 54.9 0.0 2.2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD24724.1 - 1.6e-12 47.3 0.0 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 PVD24724.1 - 3.1e-05 23.5 0.0 0.00014 21.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 PVD24724.1 - 0.016 15.6 0.0 0.063 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain WIF PF02019.18 PVD24726.1 - 1.7e-13 50.4 0.0 2.6e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.13 PVD24726.1 - 2.1e-12 47.1 41.9 5.8e-06 26.6 6.7 3.4 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.27 PVD24726.1 - 2.2e-09 37.4 40.9 6.2e-06 26.4 7.0 3.4 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 PVD24726.1 - 0.002 18.7 35.7 0.012 16.3 6.0 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF Laminin_EGF PF00053.24 PVD24726.1 - 1.9 8.7 33.9 3.7 7.8 7.2 3.4 2 1 1 3 3 3 0 Laminin EGF domain CBM_14 PF01607.24 PVD24727.1 - 6.9e-11 42.1 23.1 1.6e-07 31.4 2.9 4.4 4 1 0 4 4 4 3 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 PVD24727.1 - 0.026 14.2 7.6 0.44 10.2 0.2 3.2 2 1 0 3 3 3 0 Viral capsid protein 91 N-terminal CBM_14 PF01607.24 PVD24728.1 - 9.1e-11 41.8 26.3 1.4e-06 28.3 1.2 3.7 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain Synapsin_C PF02750.14 PVD24729.1 - 1.9e-102 341.1 0.0 2.6e-102 340.6 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 PVD24729.1 - 4.2e-36 123.3 0.0 4.1e-35 120.1 0.0 2.3 2 0 0 2 2 2 1 Synapsin, N-terminal domain Metal_resist PF13801.6 PVD24729.1 - 0.37 11.0 4.2 0.29 11.3 2.4 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF1041 PF06292.17 PVD24731.1 - 4.4e-33 113.8 2.2 1.9e-32 111.8 2.2 2.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.29 PVD24731.1 - 2.9e-10 40.6 0.1 9.4e-10 38.9 0.1 2.0 1 0 0 1 1 1 1 PH domain PHD PF00628.29 PVD24732.1 - 1.8e-07 30.9 14.4 4.5e-07 29.7 14.4 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 PVD24732.1 - 2.4e-06 28.1 2.0 2.4e-06 28.1 2.0 3.6 3 2 0 3 3 3 1 SET domain PHD_2 PF13831.6 PVD24732.1 - 0.037 13.6 11.2 0.096 12.3 11.2 1.7 1 0 0 1 1 1 0 PHD-finger HDNR PF15115.6 PVD24733.1 - 2.4e-21 76.7 0.9 3.2e-21 76.3 0.9 1.3 1 1 0 1 1 1 1 Domain of unknown function with conserved HDNR motif Innate_immun PF12782.7 PVD24734.1 - 7.8 5.9 10.6 0.046 13.2 1.8 1.6 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Pkinase PF00069.25 PVD24735.1 - 3e-61 207.1 0.1 6.6e-61 206.0 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24735.1 - 2.1e-46 158.3 0.2 3.8e-46 157.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD24735.1 - 4.1e-06 26.3 0.2 1.1e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD24735.1 - 0.0014 18.0 1.6 0.019 14.4 1.6 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD24735.1 - 0.0015 18.5 1.3 0.0059 16.6 1.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family SPOC PF07744.13 PVD24736.1 - 1.2e-36 125.9 0.0 1.8e-35 122.0 0.0 2.1 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 PVD24736.1 - 1.7e-28 98.3 0.0 4.3e-16 58.5 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD24736.1 - 0.00061 19.9 0.6 0.73 10.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 PVD24736.1 - 0.013 15.5 0.0 0.34 11.0 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Nup35_RRM_2 PF14605.6 PVD24736.1 - 0.096 12.7 0.1 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SMN PF06003.12 PVD24736.1 - 6.6 5.9 8.1 13 4.9 8.1 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pkinase PF00069.25 PVD24737.1 - 2.4e-65 220.5 0.0 3.5e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24737.1 - 4.5e-30 104.8 0.0 6.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD24737.1 - 2.6e-06 27.0 0.3 4.1e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD24737.1 - 0.00044 19.7 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD24737.1 - 0.0068 16.3 0.1 0.037 14.0 0.1 1.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 PVD24737.1 - 0.02 14.5 0.1 3 7.4 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PVD24737.1 - 0.069 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 PVD24737.1 - 0.069 12.7 1.3 0.076 12.6 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF4371 PF14291.6 PVD24738.1 - 3.8e-08 33.3 0.1 7.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 PVD24738.1 - 0.0047 16.7 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 PVD24738.1 - 0.021 14.7 0.2 0.048 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) VapB_antitoxin PF09957.9 PVD24739.1 - 0.0014 18.5 0.0 1.7e+02 2.2 0.0 5.4 6 0 0 6 6 6 0 Bacterial antitoxin of type II TA system, VapB dCMP_cyt_deam_1 PF00383.23 PVD24739.1 - 2.2 8.2 6.2 14 5.7 1.0 3.2 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region tRNA_bind PF01588.20 PVD24739.1 - 9.3 6.4 12.6 47 4.2 0.2 4.3 2 2 2 4 4 4 0 Putative tRNA binding domain Sugar_tr PF00083.24 PVD24740.1 - 5.2e-96 322.3 19.9 3.5e-81 273.4 12.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD24740.1 - 9.8e-29 100.4 18.9 9.8e-29 100.4 18.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 PVD24740.1 - 0.036 13.9 5.1 0.23 11.3 0.0 3.2 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Caveolin PF01146.17 PVD24741.1 - 1.6e-20 73.4 11.6 4.3e-19 68.8 8.8 2.0 1 1 1 2 2 2 2 Caveolin Thioredoxin_7 PF13899.6 PVD24742.1 - 2.4e-14 53.3 0.2 4.6e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 PVD24742.1 - 6.7e-14 51.4 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 PVD24742.1 - 9e-13 48.2 0.0 1.9e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 PVD24742.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 PVD24742.1 - 0.098 12.6 0.2 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF255 TAP_C PF03943.13 PVD24742.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain zf-CCCH_4 PF18044.1 PVD24743.1 - 1.6e-25 88.4 34.9 5.4e-09 35.6 3.2 4.7 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD24743.1 - 4.7e-22 77.3 38.8 1.9e-07 30.9 5.7 5.0 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 PVD24743.1 - 1.3e-17 63.2 31.6 3.1e-07 30.1 2.1 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PVD24743.1 - 4.6e-15 56.2 17.0 9.3e-05 23.1 0.6 4.7 3 1 1 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 PVD24743.1 - 2e-10 40.7 30.7 0.01 16.3 5.7 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PVD24743.1 - 2.5e-08 34.1 13.2 9.3e-08 32.3 3.3 3.4 3 0 0 3 3 3 1 Zinc-finger containing family zf-RING_2 PF13639.6 PVD24743.1 - 0.00015 22.0 12.3 0.00015 22.0 12.3 3.1 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 PVD24743.1 - 0.00072 19.4 12.5 0.00072 19.4 12.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD24743.1 - 0.0019 18.2 6.9 0.0054 16.7 6.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD24743.1 - 0.25 11.7 16.6 0.071 13.4 11.0 3.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD24743.1 - 0.26 11.1 5.9 0.8 9.5 5.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 PVD24743.1 - 0.66 10.0 16.3 0.14 12.2 11.7 2.4 2 0 0 2 2 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD24743.1 - 1.1 9.5 15.8 0.1 12.8 9.5 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD24743.1 - 2 8.3 12.2 25 4.8 11.8 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 PVD24744.1 - 7.7e-42 143.5 0.0 1.4e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24744.1 - 4.7e-29 101.5 0.0 1.1e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 PVD24744.1 - 1.1e-07 31.6 2.1 3.2e-07 30.2 0.2 2.4 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain TBK1_CCD1 PF18394.1 PVD24744.1 - 4.5e-06 26.4 11.8 5.3e-06 26.2 7.6 2.4 1 1 1 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 APH PF01636.23 PVD24744.1 - 0.058 13.3 0.3 6.1 6.7 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Snapin_Pallidin PF14712.6 PVD24744.1 - 6.6 7.2 12.7 8.1 7.0 0.1 4.4 4 0 0 4 4 4 0 Snapin/Pallidin Q_salvage PF10343.9 PVD24747.1 - 6.3e-67 226.1 0.0 9e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Trypsin PF00089.26 PVD24747.1 - 4.5e-38 131.3 0.1 8.1e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Trypsin DUF1688 PF07958.11 PVD24747.1 - 0.13 10.9 0.0 0.28 9.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1688) Ank_2 PF12796.7 PVD24748.1 - 1.8e-32 111.8 2.5 1e-09 38.8 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD24748.1 - 2.1e-31 107.0 8.7 1.5e-05 25.2 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 PVD24748.1 - 8.1e-30 102.8 4.6 4.9e-13 49.3 0.1 5.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD24748.1 - 1.2e-28 98.8 9.5 1.4e-07 31.6 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD24748.1 - 2.8e-28 94.8 10.4 7.8e-05 22.8 0.1 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ras PF00071.22 PVD24749.1 - 5.3e-59 198.5 0.9 6.1e-59 198.2 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24749.1 - 6.5e-36 123.2 0.5 9.2e-36 122.7 0.5 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24749.1 - 2.2e-15 56.5 0.2 2.7e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD24749.1 - 1e-05 25.0 0.1 1.3e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PVD24749.1 - 0.0014 18.4 0.4 0.096 12.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 PVD24749.1 - 0.0026 17.8 0.2 0.0038 17.2 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PVD24749.1 - 0.0039 17.2 0.2 0.007 16.4 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD24749.1 - 0.0056 17.1 0.2 0.014 15.8 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 PVD24749.1 - 0.0061 16.0 0.2 0.013 15.0 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PVD24749.1 - 0.0078 16.0 0.1 0.015 15.0 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PVD24749.1 - 0.015 15.6 0.4 0.03 14.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD24749.1 - 0.025 14.1 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PVD24749.1 - 0.046 13.6 1.5 3.4 7.6 0.1 2.4 1 1 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 PVD24749.1 - 0.053 13.5 0.3 0.14 12.1 0.3 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PVD24749.1 - 0.061 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 PVD24749.1 - 0.077 12.5 0.8 0.36 10.4 0.8 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 PVD24749.1 - 0.11 11.9 0.2 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein GST_C_3 PF14497.6 PVD24750.1 - 4.2e-16 59.0 0.0 6.2e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD24750.1 - 6.7e-12 45.5 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD24750.1 - 1.1e-10 41.7 0.0 2.7e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD24750.1 - 0.00082 19.3 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD24750.1 - 0.0015 18.9 0.0 0.0045 17.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD24751.1 - 2.1e-15 56.7 0.0 3.2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD24751.1 - 5.9e-13 49.0 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD24751.1 - 1.7e-12 47.4 0.0 3.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD24751.1 - 0.0024 18.2 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Soc PF16855.5 PVD24751.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Small outer capsid protein FUR PF01475.19 PVD24752.1 - 0.035 14.2 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Ferric uptake regulator family ANAPC2 PF08672.11 PVD24752.1 - 0.057 13.9 0.0 13 6.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 AGH PF17558.2 PVD24752.1 - 1.9 8.7 5.9 0.25 11.5 1.0 2.1 3 0 0 3 3 3 0 Androgenic gland hormone Sec7 PF01369.20 PVD24754.1 - 1.3e-66 223.8 0.1 2.4e-66 222.9 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 PVD24754.1 - 9.9e-61 203.7 0.7 9.9e-61 203.7 0.7 1.7 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 PVD24754.1 - 0.095 12.5 1.4 0.6 9.9 1.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PLU-1 PF08429.11 PVD24755.1 - 5.2e-91 305.3 6.8 5.2e-91 305.3 6.8 3.4 4 0 0 4 4 4 2 PLU-1-like protein JmjC PF02373.22 PVD24755.1 - 1.4e-42 144.7 0.7 3.4e-42 143.5 0.7 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 PVD24755.1 - 7e-17 61.9 0.1 1.9e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 PVD24755.1 - 7.4e-17 61.5 14.8 7.4e-17 61.5 14.8 2.9 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.17 PVD24755.1 - 3.9e-16 58.7 0.4 8.7e-16 57.6 0.4 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 PVD24755.1 - 1.9e-12 46.9 27.9 2.4e-08 33.8 2.1 3.1 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 PVD24755.1 - 0.04 13.5 6.9 0.24 11.0 5.7 2.5 2 0 0 2 2 2 0 PHD-finger CCDC-167 PF15188.6 PVD24756.1 - 0.015 15.6 0.2 0.015 15.6 0.2 5.1 4 1 1 5 5 5 0 Coiled-coil domain-containing protein 167 BING4CT PF08149.11 PVD24756.1 - 0.27 11.0 1.4 0.91 9.4 1.4 1.9 1 0 0 1 1 1 0 BING4CT (NUC141) domain Atg14 PF10186.9 PVD24756.1 - 0.63 9.1 34.7 0.033 13.3 0.5 3.2 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DIT1_PvcA PF05141.12 PVD24756.1 - 1.1 8.6 10.4 22 4.4 9.6 2.7 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein TPD52 PF04201.15 PVD24756.1 - 8 6.0 11.2 0.13 11.8 1.9 2.6 2 1 1 3 3 3 0 Tumour protein D52 family IFT57 PF10498.9 PVD24756.1 - 8.1 5.3 32.2 66 2.3 20.6 3.3 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 PVD24756.1 - 9.9 6.6 44.4 0.75 10.2 11.6 3.7 1 1 1 2 2 2 0 Fez1 Trypsin PF00089.26 PVD24757.1 - 2.1e-56 191.2 0.3 3.7e-56 190.4 0.3 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD24757.1 - 2.8e-06 28.3 0.1 6.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain CBM_14 PF01607.24 PVD24757.1 - 0.0069 16.5 3.1 0.0069 16.5 3.1 2.3 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain DUF316 PF03761.15 PVD24757.1 - 0.094 12.3 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 THOC7 PF05615.13 PVD24758.1 - 5.8e-36 123.7 12.1 5.8e-36 123.7 12.1 2.1 2 0 0 2 2 2 1 Tho complex subunit 7 Phage_1_1 PF08200.11 PVD24758.1 - 0.048 14.1 2.2 0.16 12.4 2.2 1.9 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Peptidase_S46 PF10459.9 PVD24758.1 - 0.074 11.7 13.6 0.087 11.5 13.6 1.0 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S10 PF00450.22 PVD24758.1 - 0.082 12.3 2.5 0.093 12.1 2.5 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase PDGF_N PF04692.13 PVD24758.1 - 0.11 13.3 0.3 0.11 13.3 0.3 3.2 1 1 2 3 3 3 0 Platelet-derived growth factor, N terminal region RasGAP_C PF03836.15 PVD24758.1 - 0.16 12.1 16.4 0.32 11.1 4.1 2.5 1 1 1 2 2 2 0 RasGAP C-terminus FUSC PF04632.12 PVD24758.1 - 0.18 10.3 6.7 0.23 10.0 6.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Biliv-reduc_cat PF09166.10 PVD24758.1 - 0.19 12.1 2.8 0.36 11.1 1.2 2.1 1 1 1 2 2 2 0 Biliverdin reductase, catalytic DUF4407 PF14362.6 PVD24758.1 - 0.27 10.5 12.0 0.42 9.9 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRCR_2 PF15494.6 PVD24758.1 - 0.34 11.5 2.3 0.54 10.8 0.4 2.0 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Exonuc_VII_L PF02601.15 PVD24758.1 - 0.48 10.0 14.0 0.56 9.7 14.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4239 PF14023.6 PVD24758.1 - 1.9 8.2 9.2 0.26 11.0 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Osteoregulin PF07175.11 PVD24758.1 - 2.3 8.4 8.8 2.5 8.3 5.2 2.1 1 1 1 2 2 2 0 Osteoregulin HAUS6_N PF14661.6 PVD24758.1 - 2.7 7.5 23.7 0.32 10.6 11.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 PVD24758.1 - 2.9 6.4 17.3 4.6 5.7 17.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Mod_r PF07200.13 PVD24758.1 - 3.2 7.8 27.4 1 9.4 10.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3347 PF11827.8 PVD24758.1 - 3.5 7.8 13.1 1.6 8.9 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) NPV_P10 PF05531.12 PVD24758.1 - 4.6 7.8 8.5 97 3.5 7.9 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 PVD24758.1 - 6 4.7 14.6 7.2 4.4 14.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 PVD24758.1 - 7 5.4 13.9 7.7 5.3 13.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FemAB PF02388.16 PVD24758.1 - 7.1 5.4 13.7 12 4.6 13.5 1.4 1 1 0 1 1 1 0 FemAB family SCA7 PF08313.12 PVD24759.1 - 6.7e-26 90.0 1.6 1.3e-25 89.0 1.6 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain OrsD PF12013.8 PVD24759.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Innate_immun PF12782.7 PVD24759.1 - 1 8.8 5.7 2 7.9 5.7 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SelP_N PF04592.14 PVD24759.1 - 6 6.2 10.3 12 5.3 10.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_C1 PF00112.23 PVD24760.1 - 7.9e-61 205.9 0.1 1.2e-60 205.3 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 PVD24760.1 - 5.3e-44 149.4 1.0 9.2e-44 148.6 1.0 1.4 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 PVD24760.1 - 2.8e-05 23.1 0.2 0.00097 18.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Arf PF00025.21 PVD24761.1 - 1.6e-44 151.4 0.1 1.8e-44 151.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PVD24761.1 - 5.3e-20 71.7 0.0 5.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24761.1 - 9.8e-17 61.3 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PVD24761.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD24761.1 - 3.1e-08 33.2 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD24761.1 - 3.1e-08 33.2 0.1 3.5e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PVD24761.1 - 6.3e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD24761.1 - 0.0072 16.4 0.0 2.7 8.0 0.1 2.2 1 1 1 2 2 2 2 Dynamin family Pkinase PF00069.25 PVD24763.1 - 4.3e-68 229.6 0.0 5.7e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24763.1 - 5.8e-32 111.0 0.0 8.8e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD24763.1 - 0.00032 20.1 0.6 0.00065 19.1 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD24763.1 - 0.0029 17.6 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD24763.1 - 0.0033 16.8 0.1 0.012 15.0 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PVD24763.1 - 0.015 14.3 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 PVD24763.1 - 0.035 13.7 0.2 0.074 12.6 0.2 1.6 1 1 0 1 1 1 0 RIO1 family RRM_7 PF16367.5 PVD24764.1 - 9.6e-33 112.2 0.1 2.6e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 PVD24764.1 - 1.1e-23 83.2 7.6 1.1e-23 83.2 7.6 2.9 4 0 0 4 4 4 1 Cytoplasmic polyadenylation element-binding protein ZZ domain CEBP1_N PF16368.5 PVD24764.1 - 8.4e-19 68.2 3.4 2.3e-14 53.7 0.1 2.5 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_1 PF00076.22 PVD24764.1 - 9.8e-07 28.5 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRODH PF18327.1 PVD24764.1 - 0.84 9.9 4.5 0.35 11.1 0.2 2.3 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain COMM_domain PF07258.14 PVD24765.1 - 7e-19 67.7 0.1 1.3e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 COMM domain WD40 PF00400.32 PVD24767.1 - 4.8e-09 36.7 18.3 0.00066 20.4 0.3 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat DUF4829 PF16111.5 PVD24767.1 - 1.8 9.3 5.5 0.59 10.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4829) EF-hand_7 PF13499.6 PVD24768.1 - 0.0046 17.4 0.0 6.5 7.3 0.1 3.5 2 0 0 2 2 2 2 EF-hand domain pair DUF4541 PF15074.6 PVD24769.1 - 0.00048 20.7 0.1 0.0011 19.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4541) FAM183 PF14886.6 PVD24769.1 - 0.0017 19.0 1.8 0.0059 17.3 1.8 2.2 1 1 0 1 1 1 1 FAM183A and FAM183B related F-box-like PF12937.7 PVD24770.1 - 2.3e-14 53.0 1.0 6e-14 51.7 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD24770.1 - 7.3e-12 44.9 0.6 7.3e-12 44.9 0.6 2.9 4 0 0 4 4 4 1 F-box domain LRR_4 PF12799.7 PVD24770.1 - 4.9e-09 36.3 2.1 0.001 19.4 0.3 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD24770.1 - 1.5e-07 30.9 13.6 0.062 13.4 0.1 4.7 4 0 0 4 4 4 3 Leucine Rich repeat Hemerythrin PF01814.23 PVD24770.1 - 6.6e-06 26.8 8.4 0.00043 20.9 2.1 2.4 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_1 PF00560.33 PVD24770.1 - 0.0014 18.9 10.7 0.66 10.8 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 PVD24770.1 - 1.2 9.0 6.8 18 5.2 0.4 3.7 2 2 1 3 3 3 0 Leucine rich repeat Pkinase PF00069.25 PVD24771.1 - 3.5e-58 197.0 0.0 4.3e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24771.1 - 2.1e-23 83.0 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD24771.1 - 1.5e-06 28.3 0.0 0.00026 21.0 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PVD24771.1 - 0.00068 19.3 1.5 0.0017 18.0 1.5 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PVD24771.1 - 0.0028 17.3 2.3 0.0045 16.6 2.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 PVD24771.1 - 0.012 15.1 1.9 0.036 13.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 PVD24771.1 - 0.056 12.8 1.0 0.089 12.1 1.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.20 PVD24773.1 - 1.2e-132 443.1 9.9 1.6e-132 442.8 9.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 PVD24773.1 - 2.6e-59 199.7 0.4 7e-59 198.3 0.4 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 PVD24773.1 - 6.5e-39 132.6 0.0 1.6e-38 131.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 PVD24773.1 - 6.7e-16 58.5 1.8 1.1e-06 28.9 0.0 6.1 3 2 4 7 7 7 2 HEAT repeats Cnd1 PF12717.7 PVD24773.1 - 1.1e-09 38.5 16.2 2.8e-06 27.5 0.4 4.6 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PVD24773.1 - 3e-05 23.9 5.7 12 6.5 0.4 6.6 6 0 0 6 6 6 2 HEAT repeat B2-adapt-app_C PF09066.10 PVD24773.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.6 PVD24773.1 - 0.3 11.6 5.3 3.8 8.1 0.2 4.8 5 1 2 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.16 PVD24773.1 - 0.78 10.6 2.3 22 6.1 0.1 4.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat RabGAP-TBC PF00566.18 PVD24774.1 - 8.9e-45 153.0 0.5 2.8e-44 151.4 0.5 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Histone_H2A_C PF16211.5 PVD24775.1 - 7.8e-14 51.1 0.2 7.4e-13 48.0 0.1 2.1 2 0 0 2 2 2 1 C-terminus of histone H2A Pyr_redox_2 PF07992.14 PVD24776.1 - 3.2e-56 190.7 0.0 4.6e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PVD24776.1 - 1.9e-29 102.1 0.1 3.2e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.24 PVD24776.1 - 8.1e-21 74.0 0.6 4e-20 71.8 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin Pyr_redox PF00070.27 PVD24776.1 - 2.1e-17 63.4 2.1 8.7e-13 48.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD24776.1 - 8.9e-14 51.4 0.1 2.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD24776.1 - 1.8e-08 33.9 0.3 4.7e-07 29.2 0.5 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 PVD24776.1 - 1.1e-05 25.1 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PVD24776.1 - 1.4e-05 24.4 0.1 2.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PVD24776.1 - 9.9e-05 21.7 0.0 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PVD24776.1 - 0.00016 20.5 0.5 0.00029 19.7 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 PVD24776.1 - 0.00022 20.9 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF836 PF05768.14 PVD24776.1 - 0.0008 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thi4 PF01946.17 PVD24776.1 - 0.0012 18.2 0.2 0.0027 17.0 0.2 1.6 1 0 0 1 1 1 1 Thi4 family Thioredoxin_3 PF13192.6 PVD24776.1 - 0.016 15.2 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin domain NAD_binding_8 PF13450.6 PVD24776.1 - 0.016 15.4 0.3 0.016 15.4 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thioredoxin_2 PF13098.6 PVD24776.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 PVD24776.1 - 0.058 13.6 0.6 7.1 6.8 0.2 3.0 2 1 1 3 3 3 0 Thioredoxin GST_N_3 PF13417.6 PVD24776.1 - 0.067 13.6 0.0 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Lycopene_cycl PF05834.12 PVD24776.1 - 0.14 11.1 0.4 0.25 10.4 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TraF PF13728.6 PVD24776.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein VirB3 PF05101.13 PVD24777.1 - 0.032 14.4 0.3 0.049 13.9 0.3 1.3 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Prefoldin PF02996.17 PVD24778.1 - 6.5e-19 68.0 1.3 8.2e-19 67.7 1.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 PVD24778.1 - 0.0026 17.7 1.2 1 9.3 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit YtzH PF14165.6 PVD24778.1 - 0.037 14.4 0.5 1.9 8.9 0.3 2.3 2 0 0 2 2 2 0 YtzH-like protein YojJ PF10372.9 PVD24778.1 - 2 8.6 5.3 15 5.8 0.2 2.8 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus EMC3_TMCO1 PF01956.16 PVD24779.1 - 2.3e-52 177.1 0.8 2.3e-52 177.1 0.8 1.9 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like TBK1_CCD1 PF18394.1 PVD24780.1 - 1e-27 97.3 15.9 2e-27 96.4 15.9 1.5 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase PF00069.25 PVD24780.1 - 1.1e-25 90.6 0.1 3.3e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24780.1 - 5.2e-22 78.4 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 PVD24780.1 - 9.6e-15 54.3 0.1 3.3e-14 52.6 0.1 1.9 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Kdo PF06293.14 PVD24780.1 - 2.2e-05 23.9 0.1 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ubiquitin PF00240.23 PVD24780.1 - 0.0008 19.1 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF3450 PF11932.8 PVD24780.1 - 0.0034 16.7 13.3 0.077 12.3 4.8 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) UxaC PF02614.14 PVD24780.1 - 0.0078 15.1 0.7 0.029 13.2 0.1 1.9 2 0 0 2 2 2 1 Glucuronate isomerase APH PF01636.23 PVD24780.1 - 0.023 14.6 0.5 9.9 6.0 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF885 PF05960.11 PVD24780.1 - 0.07 12.8 1.5 0.4 10.3 0.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) HisKA_3 PF07730.13 PVD24780.1 - 0.53 10.8 5.9 1.5 9.4 0.2 3.5 4 0 0 4 4 3 0 Histidine kinase DUF948 PF06103.11 PVD24780.1 - 0.71 10.2 11.2 18 5.7 0.4 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TIP120 PF08623.10 PVD24780.1 - 5.9 6.6 6.6 1.8 8.3 0.1 2.8 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF1664 PF07889.12 PVD24780.1 - 6.8 6.7 11.0 0.56 10.2 0.3 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Hormone_recep PF00104.30 PVD24782.1 - 1e-14 54.6 0.1 2.3e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hormone_recep PF00104.30 PVD24783.1 - 8.8e-20 71.2 4.8 1.5e-19 70.4 4.8 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor WD40 PF00400.32 PVD24784.1 - 1.7e-59 196.3 24.1 2.3e-08 34.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD24784.1 - 2.9e-20 72.4 0.3 4.4e-05 23.7 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD24784.1 - 9.4e-11 41.2 6.6 0.064 12.2 0.1 6.0 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD24784.1 - 8.7e-09 35.5 0.1 0.014 15.2 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 PVD24784.1 - 0.00023 19.6 0.1 0.047 12.0 0.1 2.5 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz UPF0184 PF03670.13 PVD24784.1 - 0.0018 18.7 0.1 0.004 17.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) WD40_like PF17005.5 PVD24784.1 - 0.0024 17.3 0.0 0.6 9.4 0.0 3.5 3 1 1 4 4 4 1 WD40-like domain HPS3_N PF14761.6 PVD24784.1 - 0.13 11.8 0.0 0.53 9.8 0.0 2.0 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Sulfotransfer_2 PF03567.14 PVD24785.1 - 7.3e-52 176.8 2.5 1.1e-51 176.3 2.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family Y_phosphatase PF00102.27 PVD24787.1 - 4.9e-101 337.2 0.1 1.6e-79 266.8 1.5 3.3 2 1 1 3 3 3 3 Protein-tyrosine phosphatase fn3 PF00041.21 PVD24787.1 - 9e-55 183.0 10.0 3.3e-17 62.6 1.0 4.4 3 1 1 4 4 4 4 Fibronectin type III domain DUF2369 PF10179.9 PVD24787.1 - 3.3e-05 24.2 0.3 0.0016 18.8 0.2 3.1 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 PVD24787.1 - 0.00016 21.5 1.2 0.051 13.5 0.0 3.6 3 1 0 3 3 3 1 Fibronectin-III type domain Pur_ac_phosph_N PF16656.5 PVD24787.1 - 0.0011 19.5 4.8 0.099 13.2 0.2 4.4 4 1 0 4 4 3 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD24787.1 - 0.0027 18.0 2.7 4 7.8 0.0 3.9 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.25 PVD24787.1 - 0.003 17.7 0.1 0.087 13.0 0.0 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD24787.1 - 0.003 17.9 0.0 0.012 15.9 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain DSPc PF00782.20 PVD24787.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PVD24787.1 - 0.0054 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD24787.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Ig_3 PF13927.6 PVD24787.1 - 0.0059 17.2 0.1 0.086 13.4 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 PVD24787.1 - 0.0059 16.8 0.5 0.049 13.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 PVD24787.1 - 0.029 14.4 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain LapA_dom PF06305.11 PVD24788.1 - 0.1 12.4 1.2 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Myelin_PLP PF01275.19 PVD24788.1 - 3.9 7.3 7.7 1.4 8.7 2.7 2.1 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) SKG6 PF08693.10 PVD24788.1 - 8.2 5.9 9.7 3.6 7.1 4.7 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_1 PF01344.25 PVD24789.1 - 5.9e-47 157.0 1.0 7.7e-09 35.0 0.2 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD24789.1 - 1.6e-27 94.8 1.8 6.3e-05 23.1 0.0 6.7 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD24789.1 - 1.4e-22 78.7 2.4 0.00099 19.0 0.7 5.9 5 0 0 5 5 5 5 Kelch motif BTB PF00651.31 PVD24789.1 - 1.2e-18 67.4 0.0 4.5e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD24789.1 - 5.5e-18 65.0 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD24789.1 - 2.2e-16 59.7 9.7 1.4e-05 25.2 0.2 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD24789.1 - 6.1e-16 58.2 1.4 0.074 13.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD24789.1 - 2.9e-15 55.9 2.9 0.0026 17.7 0.1 5.9 6 0 0 6 6 6 4 Kelch motif CENP-B_dimeris PF09026.10 PVD24789.1 - 2.8 8.4 10.6 8.6 6.8 10.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CIDE-N PF02017.15 PVD24790.1 - 2e-14 53.4 0.0 4.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 CIDE-N domain KHA PF11834.8 PVD24790.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel QRPTase_N PF02749.16 PVD24790.1 - 0.032 14.3 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Hist_deacetyl PF00850.19 PVD24791.1 - 1.1e-46 159.7 0.0 1.6e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF4228 PF14009.6 PVD24791.1 - 0.14 12.5 1.2 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) NAP PF00956.18 PVD24792.1 - 2.5e-18 66.2 19.1 1.4e-12 47.4 9.5 3.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 PVD24792.1 - 0.0014 18.6 3.5 0.0026 17.7 3.5 1.5 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 PVD24792.1 - 0.064 12.6 1.0 0.079 12.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 PVD24792.1 - 0.085 12.3 5.2 0.14 11.6 5.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CAP_N PF01213.19 PVD24794.1 - 1.8 8.0 6.6 2.1 7.8 6.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD24794.1 - 9.8 6.2 7.2 12 5.9 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator VGLL4 PF15245.6 PVD24795.1 - 5.7e-16 59.2 4.5 9.8e-15 55.2 1.8 2.9 2 1 1 3 3 3 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 PVD24795.1 - 3.7e-08 33.0 0.4 0.2 11.5 0.0 3.6 3 0 0 3 3 3 3 Vestigial/Tondu family SMN PF06003.12 PVD24795.1 - 5.8 6.1 12.1 0.15 11.3 5.4 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Sortilin-Vps10 PF15902.5 PVD24796.1 - 2.1e-85 287.2 3.4 2.7e-85 286.8 3.4 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PVD24796.1 - 1.4e-35 123.1 5.7 2.4e-35 122.4 5.7 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 PVD24796.1 - 3e-09 35.5 19.2 0.74 10.1 0.3 7.1 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_2 PF13088.6 PVD24796.1 - 9.7e-06 25.1 1.8 0.044 13.1 0.1 4.0 2 1 1 3 3 3 2 BNR repeat-like domain PSII_BNR PF14870.6 PVD24796.1 - 0.00012 21.5 1.3 0.022 14.0 0.1 3.8 3 1 1 4 4 4 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 PVD24796.1 - 0.18 12.0 1.1 2.6 8.3 0.1 3.6 2 0 0 2 2 2 0 BNR-Asp box repeat DUF4185 PF13810.6 PVD24796.1 - 0.19 10.9 4.5 0.23 10.6 1.1 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4185) ATP-synt PF00231.19 PVD24797.1 - 5.3e-78 262.6 0.2 6e-78 262.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase Radical_SAM_N PF08497.10 PVD24797.1 - 0.065 12.5 0.3 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 Radical SAM N-terminal RRM_1 PF00076.22 PVD24798.1 - 6.2e-07 29.1 0.9 1.4e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD24798.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif CENP-P PF13096.6 PVD24799.1 - 3e-13 49.8 0.1 5.2e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Cep57_MT_bd PF06657.13 PVD24799.1 - 0.041 14.3 5.5 0.15 12.5 5.5 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF1338 PF07063.13 PVD24799.1 - 0.1 11.7 0.5 1.4 8.0 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1338) MRP-S22 PF10245.9 PVD24802.1 - 3.5 7.3 4.5 39 3.9 0.1 3.4 1 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S22 DHHW PF14286.6 PVD24803.1 - 0.13 11.5 0.4 0.16 11.3 0.4 1.0 1 0 0 1 1 1 0 DHHW protein Trypan_PARP PF05887.11 PVD24803.1 - 0.4 10.7 2.3 0.51 10.3 2.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 PVD24803.1 - 1.8 8.3 5.9 2.3 8.0 5.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 PVD24803.1 - 3.8 6.2 6.9 4.1 6.1 6.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PVD24803.1 - 4 6.1 8.2 4.6 5.9 8.2 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 PVD24803.1 - 5.9 5.1 10.6 6.8 4.8 10.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3806 PF12713.7 PVD24804.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Ion_trans PF00520.31 PVD24805.1 - 6.2e-28 97.7 13.3 8e-28 97.3 13.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD24805.1 - 1.4e-17 63.8 0.0 3.3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.8 PVD24805.1 - 9.2e-15 53.9 8.5 1.6e-14 53.1 8.5 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans_2 PF07885.16 PVD24805.1 - 0.0019 18.1 2.2 0.0019 18.1 2.2 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 PVD24805.1 - 0.043 13.9 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 PVD24805.1 - 0.58 8.8 8.0 0.9 8.1 8.0 1.4 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.31 PVD24807.1 - 0.00082 18.7 0.0 0.00098 18.4 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein XK-related PF09815.9 PVD24807.1 - 0.094 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 XK-related protein DUF3399 PF11879.8 PVD24808.1 - 2.2e-06 28.0 0.4 2.6e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) MADF_DNA_bdg PF10545.9 PVD24811.1 - 7e-06 26.3 1.7 7e-06 26.3 1.7 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Sdh5 PF03937.16 PVD24811.1 - 0.44 10.5 3.2 4.1 7.4 0.2 3.1 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase MITF_TFEB_C_3_N PF15951.5 PVD24812.1 - 3e-23 83.1 6.7 7.8e-23 81.8 6.7 1.7 1 0 0 1 1 1 1 MITF/TFEB/TFEC/TFE3 N-terminus HLH PF00010.26 PVD24812.1 - 3.4e-15 55.7 2.1 8.2e-15 54.5 2.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LIM PF00412.22 PVD24813.1 - 1.7e-27 95.4 48.4 3.5e-12 46.4 7.5 4.3 4 1 1 5 5 5 3 LIM domain PET PF06297.14 PVD24813.1 - 2.2e-16 59.9 0.2 4.4e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 PET Domain DUF2256 PF10013.9 PVD24813.1 - 0.25 11.5 0.1 0.25 11.5 0.1 5.4 7 1 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1451 PF07295.11 PVD24813.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.7 4 0 0 4 4 4 0 Zinc-ribbon containing domain ST7 PF04184.12 PVD24815.1 - 1.6e-285 947.7 0.2 2.1e-285 947.3 0.2 1.2 1 0 0 1 1 1 1 ST7 protein TPR_14 PF13428.6 PVD24815.1 - 0.00044 20.8 3.9 0.78 10.7 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Clathrin PF00637.20 PVD24815.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_6 PF13174.6 PVD24815.1 - 0.0016 18.9 0.0 0.0076 16.8 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD24815.1 - 0.0044 17.6 0.2 0.75 10.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD24815.1 - 0.0044 17.0 0.1 0.83 9.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5588 PF17826.1 PVD24815.1 - 0.028 13.3 0.3 0.052 12.4 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5588) TPR_1 PF00515.28 PVD24815.1 - 0.1 12.5 0.2 24 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD24815.1 - 0.28 11.7 7.1 0.96 10.0 0.0 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 PVD24816.1 - 1.5e-111 372.5 0.3 2.6e-111 371.7 0.3 1.4 1 0 0 1 1 1 1 SAC3/GANP family MCM3AP_GANP PF16769.5 PVD24816.1 - 2.4e-79 267.5 21.7 3.3e-78 263.7 21.7 2.7 1 1 0 1 1 1 1 MCM3AP domain of GANP CSN8_PSD8_EIF3K PF10075.9 PVD24816.1 - 1.4e-08 34.9 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 PVD24816.1 - 0.00019 21.2 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD24816.1 - 0.0095 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PVD24816.1 - 0.053 13.5 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CID_GANP PF16766.5 PVD24816.1 - 7.8 6.8 14.4 7.5 6.8 3.6 3.4 4 0 0 4 4 4 0 Binding region of GANP to ENY2 S-methyl_trans PF02574.16 PVD24817.1 - 5.5e-20 72.3 0.1 2.7e-19 70.0 0.1 1.7 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Aldedh PF00171.22 PVD24818.1 - 2.8e-164 547.0 0.1 3.7e-164 546.6 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PVD24818.1 - 0.062 12.8 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TSGA13 PF14994.6 PVD24819.1 - 2e-25 89.7 5.4 2e-25 89.7 5.4 2.2 2 0 0 2 2 2 2 Testis-specific gene 13 protein SLATT_fungal PF18142.1 PVD24819.1 - 2.6 8.0 9.5 0.37 10.8 1.4 3.0 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain DUF4743 PF15916.5 PVD24820.1 - 4.5e-30 104.1 0.0 7.4e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 PVD24820.1 - 5.1e-05 23.3 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pro_isomerase PF00160.21 PVD24821.1 - 2.7e-54 183.7 0.0 3.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phosducin PF02114.16 PVD24822.1 - 6.3e-66 222.0 5.0 8.1e-65 218.4 5.0 2.0 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 PVD24822.1 - 4.4e-08 33.1 0.2 7.7e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Pox_A51 PF04948.13 PVD24822.1 - 0.03 13.2 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein SseB_C PF14581.6 PVD24822.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 SseB protein C-terminal domain L_HMGIC_fpl PF10242.9 PVD24823.1 - 1.1e-49 169.1 9.9 1.1e-49 169.1 9.9 1.3 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 PVD24823.1 - 0.00016 21.5 6.9 0.00042 20.2 6.9 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family MARVEL PF01284.23 PVD24823.1 - 0.45 10.5 15.8 0.95 9.5 15.5 1.7 1 1 0 1 1 1 0 Membrane-associating domain L_HMGIC_fpl PF10242.9 PVD24824.1 - 2.9e-21 76.5 1.9 2.9e-21 76.5 1.9 1.6 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein ORC5_C PF14630.6 PVD24825.1 - 2.6e-57 194.5 0.1 3.7e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus EGF_2 PF07974.13 PVD24825.1 - 2.4e-19 69.4 135.5 0.00016 22.0 11.5 8.1 7 0 0 7 7 7 6 EGF-like domain BNR PF02012.20 PVD24825.1 - 6.9e-14 49.6 49.6 0.053 13.5 0.4 14.0 14 0 0 14 14 13 6 BNR/Asp-box repeat AAA_16 PF13191.6 PVD24825.1 - 3.1e-12 47.2 0.0 5.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain CHB_HEX_C PF03174.13 PVD24825.1 - 5e-06 26.4 0.1 68 3.5 0.0 9.6 13 1 0 13 13 13 0 Chitobiase/beta-hexosaminidase C-terminal domain Reeler PF02014.16 PVD24825.1 - 7.4e-06 26.7 0.0 2.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Reeler domain EGF_Tenascin PF18720.1 PVD24825.1 - 1.3e-05 25.1 101.1 0.018 15.1 2.9 8.0 7 0 0 7 7 7 5 Tenascin EGF domain AAA_22 PF13401.6 PVD24825.1 - 8.6e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 PVD24825.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Torsin PIF1 PF05970.14 PVD24825.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Sortilin-Vps10 PF15902.5 PVD24825.1 - 0.17 10.7 3.3 75 1.9 0.0 6.3 8 0 0 8 8 8 0 Sortilin, neurotensin receptor 3, DUF4992 PF16383.5 PVD24825.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF667 PF05018.13 PVD24826.1 - 5.6e-35 120.7 0.1 1.1e-34 119.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) OCRE PF17780.1 PVD24826.1 - 0.11 12.6 0.3 0.26 11.3 0.3 1.7 1 0 0 1 1 1 0 OCRE domain Glyco_transf_90 PF05686.12 PVD24827.1 - 6.3e-103 344.7 2.7 8e-103 344.4 2.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 TMA7 PF09072.10 PVD24827.1 - 1.4e-20 73.9 14.5 3.9e-20 72.4 14.5 1.8 1 0 0 1 1 1 1 Translation machinery associated TMA7 Glyco_trans_1_2 PF13524.6 PVD24827.1 - 0.0075 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 LRR_8 PF13855.6 PVD24828.1 - 6.7e-42 141.1 55.5 9.7e-15 54.1 0.5 8.2 5 1 4 9 9 9 8 Leucine rich repeat LRR_5 PF13306.6 PVD24828.1 - 1.9e-18 66.7 23.8 1.8e-08 34.4 1.2 5.7 4 1 2 6 6 6 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD24828.1 - 8e-17 61.1 60.9 0.00047 20.5 0.4 10.9 6 3 2 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD24828.1 - 3.8e-06 26.7 40.1 0.7 10.7 0.0 12.2 13 1 0 13 13 13 3 Leucine Rich Repeat LRRNT PF01462.18 PVD24828.1 - 0.0016 18.0 0.1 0.0039 16.8 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 PVD24828.1 - 0.096 12.2 28.7 0.18 11.3 2.2 5.1 2 1 3 5 5 5 0 Leucine-rich repeat BicD PF09730.9 PVD24829.1 - 1.1e-184 615.9 73.2 1.1e-184 615.9 73.2 2.0 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF1759 PF03564.15 PVD24829.1 - 0.0073 16.3 5.0 0.0073 16.3 5.0 5.1 6 1 1 7 7 7 1 Protein of unknown function (DUF1759) SCO1-SenC PF02630.14 PVD24829.1 - 0.13 12.2 0.3 0.44 10.5 0.3 1.9 1 0 0 1 1 1 0 SCO1/SenC Spc7 PF08317.11 PVD24829.1 - 0.31 9.9 102.2 0.48 9.2 17.6 5.6 3 3 2 5 5 5 0 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 PVD24829.1 - 8.4 5.8 12.4 1.1 8.7 0.8 4.0 3 1 1 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative Carb_anhydrase PF00194.21 PVD24830.1 - 3.1e-54 184.2 0.2 3.9e-54 183.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase LIG3_BRCT PF16759.5 PVD24830.1 - 0.0082 16.4 0.3 6.7 7.1 0.0 3.2 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain Pkinase PF00069.25 PVD24831.1 - 3.5e-59 200.3 0.0 4.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24831.1 - 9.8e-25 87.3 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD24831.1 - 9.9e-07 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD24831.1 - 0.0012 18.8 0.1 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD24831.1 - 0.0073 15.3 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PVD24831.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 PVD24831.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 PVD24831.1 - 0.087 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ThiJ_like PF17124.5 PVD24831.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like SPRY PF00622.28 PVD24832.1 - 2.9e-22 79.0 0.1 6.3e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 PVD24832.1 - 9.2e-09 35.0 9.0 9.2e-09 35.0 9.0 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD24832.1 - 0.0032 17.3 8.8 0.0032 17.3 8.8 2.8 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD24832.1 - 0.0044 17.3 11.6 0.0044 17.3 11.6 2.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD24832.1 - 0.0056 16.5 11.3 0.0056 16.5 11.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IFT20 PF14931.6 PVD24832.1 - 0.031 14.4 0.0 0.031 14.4 0.0 2.4 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 Neuralized PF07177.12 PVD24832.1 - 0.059 13.4 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Neuralized Jnk-SapK_ap_N PF09744.9 PVD24832.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.4 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 zf-C3HC4 PF00097.25 PVD24832.1 - 0.76 9.7 20.1 0.023 14.6 12.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD24832.1 - 1.3 9.1 11.4 4.5 7.4 11.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD24832.1 - 3.3 7.9 9.1 15 5.8 9.1 2.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GDI PF00996.18 PVD24833.1 - 2e-204 679.1 0.0 2.5e-204 678.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor JHD PF17811.1 PVD24834.1 - 8e-28 97.0 0.2 8e-28 97.0 0.2 2.1 2 0 0 2 2 2 1 Jumonji helical domain JmjC PF02373.22 PVD24834.1 - 3.6e-09 37.1 1.7 1.5e-07 31.8 1.7 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 PVD24834.1 - 7.6e-09 35.3 10.7 1.6e-08 34.3 10.7 1.6 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 PVD24834.1 - 2.9e-08 33.8 1.4 1.6e-07 31.3 0.1 2.5 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.6 PVD24834.1 - 0.0099 15.4 4.7 0.024 14.2 4.7 1.7 1 0 0 1 1 1 1 PHD-finger TFIIE_alpha PF02002.17 PVD24834.1 - 0.099 12.5 0.0 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit PHD_4 PF16866.5 PVD24834.1 - 0.4 10.8 10.5 0.4 10.8 7.4 2.4 2 0 0 2 2 2 0 PHD-finger zf-TFIIB PF13453.6 PVD24834.1 - 9 5.7 6.5 2.1 7.8 2.4 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger FancD2 PF14631.6 PVD24835.1 - 0 1103.0 48.0 4.6e-135 451.9 15.1 3.0 1 1 2 3 3 3 3 Fanconi anaemia protein FancD2 nuclease CNOT11 PF10155.9 PVD24835.1 - 0.093 12.9 5.3 1.6 8.9 0.1 4.4 4 0 0 4 4 4 0 CCR4-NOT transcription complex subunit 11 MA3 PF02847.17 PVD24835.1 - 8.5 6.4 7.7 0.9 9.5 0.1 3.3 4 0 0 4 4 4 0 MA3 domain MDM1 PF15501.6 PVD24837.1 - 8.7e-65 219.9 35.8 8.7e-64 216.6 35.8 2.2 1 1 0 1 1 1 1 Nuclear protein MDM1 tRNA_Me_trans PF03054.16 PVD24838.1 - 1.5e-111 372.7 0.0 3.1e-55 187.4 0.0 2.0 1 1 1 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 PVD24838.1 - 7.3e-09 35.1 0.0 1.7e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 NAD synthase ThiI PF02568.14 PVD24838.1 - 5.7e-05 22.8 0.0 0.00014 21.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 PVD24838.1 - 0.0028 17.2 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 PVD24838.1 - 0.027 14.1 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase Serum_albumin PF00273.20 PVD24839.1 - 0.098 12.4 21.7 1.2 8.9 3.2 2.6 1 1 1 2 2 2 0 Serum albumin family 7tm_2 PF00002.24 PVD24840.1 - 1.1e-39 136.2 22.0 1.6e-39 135.6 22.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 PVD24840.1 - 1.1e-12 48.3 3.9 1.1e-12 48.3 3.9 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Frizzled PF01534.17 PVD24840.1 - 0.00032 19.8 12.1 0.00032 19.8 12.1 2.1 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region Lectin_C PF00059.21 PVD24840.1 - 0.00049 20.8 4.7 0.19 12.4 0.1 4.3 3 1 0 3 3 3 2 Lectin C-type domain Glu-tRNAGln PF02686.15 PVD24840.1 - 0.064 13.6 0.1 0.33 11.3 0.1 2.3 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit 7tm_1 PF00001.21 PVD24841.1 - 1.4e-33 116.4 12.3 1.7e-33 116.1 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD24841.1 - 2.2e-05 24.3 11.1 0.027 14.2 7.5 2.2 2 0 0 2 2 2 2 Olfactory receptor Phage_Gp23 PF10669.9 PVD24841.1 - 0.037 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4436 PF14494.6 PVD24841.1 - 0.24 10.6 5.7 0.13 11.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4436) Amnionless PF14828.6 PVD24841.1 - 0.67 8.7 3.2 9.7 4.9 0.1 2.1 1 1 0 2 2 2 0 Amnionless L_HMGIC_fpl PF10242.9 PVD24841.1 - 1.9 8.7 13.8 0.26 11.5 7.9 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Peptidase_M20 PF01546.28 PVD24842.1 - 3.6e-38 131.3 0.0 5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PVD24842.1 - 4.3e-15 55.6 0.0 7.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PVD24842.1 - 6.7e-05 22.7 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 FluMu_N PF17891.1 PVD24842.1 - 0.12 12.2 0.9 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain SHIPPO-rpt PF07004.12 PVD24843.1 - 0.0004 21.2 38.1 0.53 11.3 0.0 9.4 9 1 0 9 9 9 4 Sperm-tail PG-rich repeat Cytochrom_B559a PF00284.20 PVD24843.1 - 1.3 8.8 6.6 1e+02 2.8 0.1 5.0 5 0 0 5 5 5 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Hydrolase_like PF13242.6 PVD24844.1 - 2.5e-07 30.6 0.0 2.1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 HAD-hyrolase-like Peptidase_M1 PF01433.20 PVD24845.1 - 2.6e-42 144.9 0.0 4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PVD24845.1 - 4.3e-37 126.7 0.3 7.5e-37 125.9 0.3 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PVD24845.1 - 2.6e-12 47.3 0.0 1.1e-11 45.2 0.0 1.9 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain TMEM154 PF15102.6 PVD24846.1 - 0.0033 17.3 0.6 0.0046 16.9 0.6 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.8 PVD24846.1 - 0.0093 15.9 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 PVD24846.1 - 0.057 14.3 0.0 0.074 13.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 PVD24846.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF5305 PF17231.2 PVD24846.1 - 0.14 11.5 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) POT1 PF02765.17 PVD24847.1 - 7.5e-24 84.2 0.0 2.1e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 PVD24847.1 - 6.7e-10 39.0 0.0 3.6e-09 36.7 0.0 2.2 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein Usp PF00582.26 PVD24848.1 - 8.1e-19 68.5 1.7 1.7e-16 61.0 0.7 2.1 1 1 1 2 2 2 2 Universal stress protein family DUF2726 PF10881.8 PVD24848.1 - 0.034 14.1 0.3 0.17 11.7 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2726) DUF4145 PF13643.6 PVD24848.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) DUF1943 PF09172.11 PVD24848.1 - 0.12 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Usp PF00582.26 PVD24849.1 - 5.9e-15 56.0 0.0 6.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 PVD24850.1 - 0.0045 17.5 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 PVD24851.1 - 4.1e-05 24.1 0.0 5e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Beta-Casp PF10996.8 PVD24851.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 Beta-Casp domain Aminotran_1_2 PF00155.21 PVD24852.1 - 3e-32 112.2 0.0 1.1e-31 110.3 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PVD24852.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Rhodanese PF00581.20 PVD24854.1 - 1.9e-12 47.6 0.0 3.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 PVD24854.1 - 3e-11 43.3 0.0 6.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Dynamin_M PF01031.20 PVD24856.1 - 1e-86 290.7 1.8 1.2e-86 290.5 0.0 2.0 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 PVD24856.1 - 5.6e-50 169.7 0.2 6.7e-49 166.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 PVD24856.1 - 3.6e-31 107.1 5.9 8.7e-31 105.9 5.9 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Death PF00531.22 PVD24856.1 - 3.2e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Death domain MMR_HSR1 PF01926.23 PVD24856.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NUC202 PF08166.12 PVD24856.1 - 0.014 15.4 0.4 0.043 13.9 0.0 2.0 2 0 0 2 2 2 0 NUC202 domain AAA_16 PF13191.6 PVD24856.1 - 0.016 15.6 0.3 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain CENP-O PF09496.10 PVD24856.1 - 0.068 13.2 0.5 0.15 12.0 0.5 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component TFIIF_alpha PF05793.12 PVD24856.1 - 0.12 11.0 1.3 0.28 9.7 1.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Roc PF08477.13 PVD24856.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IMUP PF15761.5 PVD24856.1 - 5.3 7.8 12.6 0.034 14.8 3.8 1.8 2 0 0 2 2 1 0 Immortalisation up-regulated protein Usp PF00582.26 PVD24857.1 - 1.2e-27 97.2 0.0 1.5e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Ins145_P3_rec PF08709.11 PVD24858.1 - 8e-73 244.2 0.0 3.2e-72 242.2 0.1 2.0 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 PVD24858.1 - 2.3e-66 223.2 0.0 2.2e-64 216.8 0.0 2.7 2 0 0 2 2 2 1 MIR domain RYDR_ITPR PF01365.21 PVD24858.1 - 5.5e-33 114.1 25.3 6.3e-15 55.1 0.0 6.1 5 1 0 5 5 5 3 RIH domain RIH_assoc PF08454.11 PVD24858.1 - 2.2e-29 101.3 4.8 2.2e-29 101.3 4.8 4.8 4 0 0 4 4 4 2 RyR and IP3R Homology associated Ion_trans PF00520.31 PVD24858.1 - 1.8e-16 60.1 12.3 3.6e-16 59.1 12.3 1.5 1 0 0 1 1 1 1 Ion transport protein Pneumo_M2 PF07380.11 PVD24858.1 - 0.12 12.7 1.5 0.34 11.2 0.5 2.3 2 0 0 2 2 2 0 Pneumovirus M2 protein Pkinase_Tyr PF07714.17 PVD24859.1 - 1.1e-80 270.7 0.0 1.6e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD24859.1 - 2.6e-36 125.3 0.0 3.8e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PVD24859.1 - 1.3e-27 95.7 17.4 1.4e-13 50.7 0.6 5.7 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 PVD24859.1 - 1.3e-18 67.4 0.1 9.6e-15 55.0 0.0 3.2 2 0 0 2 2 2 2 TIG domain found in plexin Sema PF01403.19 PVD24859.1 - 7.1e-16 58.0 0.0 4.7e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 Sema domain PSI PF01437.25 PVD24859.1 - 5.9e-14 52.3 53.9 4.5e-06 27.1 12.9 3.8 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 PVD24859.1 - 8.1e-08 32.2 6.9 8.5e-06 25.7 0.1 4.1 4 0 0 4 4 4 2 TIG domain Transport_MerF PF11431.8 PVD24859.1 - 0.068 13.1 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Membrane transport protein MerF PSI_integrin PF17205.3 PVD24859.1 - 2.5 7.9 50.4 0.032 14.0 10.2 3.9 4 0 0 4 4 4 0 Integrin plexin domain LRR_8 PF13855.6 PVD24860.1 - 2e-60 200.4 72.1 2.5e-13 49.6 5.3 6.7 2 1 5 7 7 7 7 Leucine rich repeat I-set PF07679.16 PVD24860.1 - 2.7e-47 158.8 0.0 9.8e-19 67.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD24860.1 - 2.4e-45 153.0 2.7 2.7e-14 53.5 0.1 4.0 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD24860.1 - 9.9e-33 112.3 0.0 6.8e-10 39.1 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD24860.1 - 2.9e-30 104.3 0.3 5.9e-10 39.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 PVD24860.1 - 2.5e-23 82.5 0.0 1.1e-07 31.8 0.0 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD24860.1 - 1.8e-20 72.6 46.9 1.4e-05 25.3 1.2 7.9 1 1 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD24860.1 - 1e-14 54.4 19.1 7.4e-06 25.6 4.7 4.9 1 1 4 6 6 6 5 Leucine-rich repeat V-set PF07686.17 PVD24860.1 - 1.2e-12 47.9 4.3 0.12 12.6 0.0 6.2 3 3 2 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD24860.1 - 9.7e-12 44.8 8.7 0.00025 21.1 0.0 4.2 5 0 0 5 5 3 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD24860.1 - 1.3e-06 27.9 0.0 1.1 8.9 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRRCT PF01463.24 PVD24860.1 - 0.00088 19.6 0.0 0.0071 16.8 0.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain UL141 PF16758.5 PVD24860.1 - 0.0015 18.3 2.3 0.18 11.5 0.0 3.7 2 1 2 4 4 4 1 Herpes-like virus membrane glycoprotein UL141 LRR_1 PF00560.33 PVD24860.1 - 0.0082 16.6 31.9 2.8 8.8 0.8 9.3 10 1 0 10 10 9 2 Leucine Rich Repeat Receptor_2B4 PF11465.8 PVD24860.1 - 0.043 14.0 0.0 5.4 7.3 0.0 3.3 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 PVD24860.1 - 0.069 13.2 0.0 2 8.5 0.0 2.9 2 0 0 2 2 2 0 C17orf99 Ig domain Izumo-Ig PF16706.5 PVD24860.1 - 0.11 12.6 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain zf-piccolo PF05715.13 PVD24860.1 - 3.6 7.8 8.0 0.78 9.9 3.5 2.2 2 0 0 2 2 2 0 Piccolo Zn-finger EGF_CA PF07645.15 PVD24862.1 - 7.7e-12 45.2 30.2 6.5e-10 39.1 5.3 6.9 4 2 2 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 PVD24862.1 - 5.3e-05 23.0 43.9 0.0096 15.8 2.5 6.4 5 1 0 5 5 5 3 Complement Clr-like EGF-like Laminin_EGF PF00053.24 PVD24862.1 - 0.00023 21.2 12.2 0.00023 21.2 12.2 6.2 2 1 4 6 6 6 1 Laminin EGF domain hEGF PF12661.7 PVD24862.1 - 0.0022 18.6 1.2 0.0022 18.6 1.2 6.9 6 0 0 6 6 6 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 PVD24862.1 - 0.0034 17.4 1.2 0.0034 17.4 1.2 5.4 6 0 0 6 6 6 2 MSP1 EGF domain 1 EGF_3 PF12947.7 PVD24862.1 - 0.0045 17.2 5.0 0.0045 17.2 5.0 6.8 6 3 1 7 7 7 1 EGF domain Plasmod_Pvs28 PF06247.11 PVD24862.1 - 0.019 15.3 5.5 0.019 15.3 5.5 5.8 5 2 0 5 5 5 0 Pvs28 EGF domain EGF PF00008.27 PVD24862.1 - 0.035 14.4 2.0 0.035 14.4 2.0 7.0 7 2 0 7 7 7 0 EGF-like domain Exo_endo_phos_2 PF14529.6 PVD24863.1 - 0.00066 19.5 0.1 0.0021 17.9 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Fam20C PF06702.12 PVD24863.1 - 0.065 13.0 1.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Golgi casein kinase, C-terminal, Fam20 PPP4R2 PF09184.11 PVD24864.1 - 1.1e-58 199.1 0.1 1.3e-58 198.8 0.1 1.1 1 0 0 1 1 1 1 PPP4R2 RVT_1 PF00078.27 PVD24866.1 - 1.8e-18 66.9 0.0 2e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Esterase PF00756.20 PVD24867.1 - 0.098 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Exo_endo_phos_2 PF14529.6 PVD24868.1 - 1.4e-16 60.4 4.4 4.7e-15 55.5 0.2 3.0 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD24868.1 - 1.8e-11 44.0 0.0 3.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Y_phosphatase PF00102.27 PVD24870.1 - 3.4e-35 121.7 0.1 5.6e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD24870.1 - 4e-06 27.0 0.2 8.2e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 PVD24870.1 - 0.00012 21.9 0.1 0.00028 20.7 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PVD24870.1 - 0.00015 21.9 0.6 0.0007 19.7 0.1 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate RVT_1 PF00078.27 PVD24871.1 - 6e-31 107.7 0.0 6.9e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDZ PF00595.24 PVD24872.1 - 3.5e-14 52.9 0.2 2.1e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD24872.1 - 7.7e-14 51.3 0.3 2.7e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PVD24872.1 - 2.6e-05 24.4 0.0 7.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GIT1_C PF12205.8 PVD24872.1 - 0.018 15.1 0.6 0.3 11.2 1.5 2.4 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Actin PF00022.19 PVD24873.1 - 1.3e-49 168.9 0.0 1.4e-48 165.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PVD24873.1 - 1.6e-06 27.2 0.0 1.2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Ig_3 PF13927.6 PVD24874.1 - 5.4e-71 235.2 4.8 6.2e-12 45.9 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 PVD24874.1 - 3.1e-61 203.5 0.3 1.1e-10 41.4 0.0 7.1 8 0 0 8 8 8 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD24874.1 - 4.8e-52 174.2 8.3 9.1e-09 35.5 0.0 6.5 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 PVD24874.1 - 2.8e-41 139.6 3.5 2.6e-07 30.7 0.1 6.6 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 PVD24874.1 - 3.8e-26 91.4 16.2 0.0014 18.8 0.0 9.6 6 4 0 6 6 6 6 Immunoglobulin V-set domain fn3 PF00041.21 PVD24874.1 - 1.3e-20 73.5 15.3 1.9e-05 24.9 0.1 6.5 7 0 0 7 7 6 4 Fibronectin type III domain Ig_6 PF18452.1 PVD24874.1 - 5.1e-10 38.8 0.3 0.36 10.4 0.0 6.3 6 0 0 6 6 6 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD24874.1 - 4.1e-09 36.4 1.4 0.0055 16.7 0.0 5.1 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD24874.1 - 1.8e-06 27.9 0.1 0.068 13.2 0.0 4.7 5 0 0 5 5 5 2 C17orf99 Ig domain Lectin_C PF00059.21 PVD24874.1 - 0.0022 18.7 0.0 0.0083 16.8 0.0 2.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD24874.1 - 0.0026 17.4 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like PKD PF00801.20 PVD24874.1 - 0.014 15.2 6.9 0.015 15.1 0.3 4.2 5 0 0 5 5 5 0 PKD domain C2-set PF05790.15 PVD24874.1 - 0.026 14.7 0.1 3.4 7.9 0.0 4.4 6 0 0 6 6 6 0 Immunoglobulin C2-set domain ASC PF00858.24 PVD24875.1 - 3.5e-47 161.4 0.0 4.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel HLH PF00010.26 PVD24876.1 - 8.1e-15 54.5 1.8 1.8e-14 53.4 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LON_substr_bdg PF02190.16 PVD24876.1 - 6.5e-14 52.3 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Mid2 PF04478.12 PVD24878.1 - 0.069 13.0 0.9 0.17 11.7 0.9 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.13 PVD24878.1 - 0.63 8.8 4.8 1 8.1 4.8 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-GRF PF06839.12 PVD24879.1 - 1.7e-13 50.4 1.9 3.6e-13 49.4 1.9 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos PF03372.23 PVD24879.1 - 0.0012 18.4 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD24879.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Ets PF00178.22 PVD24880.1 - 1.6e-34 118.2 3.7 3.3e-34 117.2 3.7 1.5 1 0 0 1 1 1 1 Ets-domain Sial-lect-inser PF09264.10 PVD24880.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion SelP_N PF04592.14 PVD24880.1 - 0.13 11.6 17.9 0.23 10.8 17.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PNISR PF15996.5 PVD24880.1 - 0.22 11.8 6.1 0.46 10.7 6.1 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hydin_ADK PF17213.3 PVD24880.1 - 1.6 9.0 8.5 3 8.1 8.5 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 PVD24880.1 - 8.2 5.5 8.8 12 4.9 8.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UQ_con PF00179.26 PVD24881.1 - 1.9e-28 98.9 0.0 2.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NUDIX PF00293.28 PVD24882.1 - 9.9e-13 48.3 0.0 7e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Pkinase PF00069.25 PVD24883.1 - 8.5e-38 130.2 6.5 5.9e-20 71.7 0.4 3.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24883.1 - 5.5e-09 35.7 0.4 4.6e-07 29.4 0.3 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD24883.1 - 0.0073 15.1 2.2 0.0078 15.0 0.3 1.8 1 1 1 2 2 2 1 Fungal protein kinase CBM_14 PF01607.24 PVD24884.1 - 4.2e-10 39.6 6.2 9.1e-10 38.6 6.2 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Polysacc_deac_1 PF01522.21 PVD24884.1 - 4.5e-06 26.6 0.1 5.1e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase Cyclase PF04199.13 PVD24885.1 - 2.9e-35 121.5 0.2 3.7e-35 121.1 0.2 1.1 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 PVD24886.1 - 1.9e-35 122.0 0.1 2.5e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase CBM_14 PF01607.24 PVD24887.1 - 1.6e-08 34.6 4.3 2.6e-08 33.9 4.3 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Polysacc_deac_1 PF01522.21 PVD24888.1 - 2.1e-07 30.8 0.1 6.6e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase 7tm_1 PF00001.21 PVD24890.1 - 2.5e-05 23.7 0.3 3.6e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Na_H_Exchanger PF00999.21 PVD24890.1 - 0.031 13.1 0.3 0.039 12.7 0.3 1.0 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Nuc_sug_transp PF04142.15 PVD24891.1 - 2.8e-111 371.7 21.3 3.5e-111 371.4 21.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PVD24891.1 - 0.00035 20.8 10.0 0.00035 20.8 10.0 3.5 2 2 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 PVD24891.1 - 0.00047 19.4 1.9 0.00047 19.4 1.9 2.7 2 2 1 3 3 3 2 UAA transporter family Nairovirus_M PF07948.11 PVD24891.1 - 0.044 12.0 0.6 0.06 11.6 0.6 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Dynein_C PF18199.1 PVD24892.1 - 1.7e-113 378.9 0.0 2.6e-113 378.3 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 PVD24892.1 - 1.2e-63 213.8 0.0 2e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD24892.1 - 2.6e-44 150.1 0.0 4.7e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 PVD24892.1 - 0.029 13.5 0.0 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 ATP-binding dynein motor region AAA_6 PF12774.7 PVD24893.1 - 1.7e-150 500.5 0.0 9.1e-150 498.1 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD24893.1 - 4.7e-121 404.6 4.2 4.7e-121 404.6 4.2 3.0 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD24893.1 - 3.7e-93 311.6 3.2 5.7e-78 261.8 0.2 3.2 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD24893.1 - 1.6e-79 265.6 0.1 1.4e-77 259.3 0.0 3.0 3 1 0 3 3 3 1 P-loop containing dynein motor region AAA_9 PF12781.7 PVD24893.1 - 1.1e-67 227.4 0.0 1.1e-67 227.4 0.0 2.6 4 0 0 4 4 3 1 ATP-binding dynein motor region MT PF12777.7 PVD24893.1 - 2.8e-33 115.4 19.1 1.4e-22 80.2 0.2 2.8 2 1 1 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 PVD24893.1 - 2.5e-18 66.4 0.0 0.0017 18.3 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD24893.1 - 1.5e-17 63.6 2.0 2.9e-17 62.7 0.1 2.6 3 0 0 3 3 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 PVD24893.1 - 9.1e-13 48.4 0.1 4.6e-11 42.9 0.1 3.2 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PVD24893.1 - 3.3e-06 27.5 0.0 0.8 10.1 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD24893.1 - 0.00011 22.6 0.1 0.17 12.3 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD24893.1 - 0.0012 19.1 0.0 0.25 11.6 0.0 3.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PVD24893.1 - 0.0013 19.0 0.0 1.3 9.4 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 PVD24893.1 - 0.0023 18.4 0.2 2.2 8.8 0.0 4.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 PVD24893.1 - 0.0069 15.5 0.3 0.032 13.3 0.0 2.2 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 PVD24893.1 - 0.014 15.5 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD24893.1 - 0.034 13.9 0.1 3.1 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 PVD24893.1 - 0.038 13.7 0.1 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad60-SLD PF11976.8 PVD24893.1 - 0.096 12.5 0.3 27 4.7 0.1 3.5 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like DASH_Dam1 PF08653.10 PVD24893.1 - 0.13 12.1 1.8 0.41 10.5 0.3 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 PH_3 PF14593.6 PVD24893.1 - 4.6 7.4 6.1 9 6.5 0.1 3.7 4 0 0 4 4 4 0 PH domain KxDL PF10241.9 PVD24893.1 - 5.9 7.3 8.1 30 5.0 0.9 4.3 3 0 0 3 3 3 0 Uncharacterized conserved protein SOUL PF04832.12 PVD24894.1 - 6.8e-47 159.8 0.0 8.5e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.12 PVD24895.1 - 1.5e-25 90.3 0.0 1.8e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein Oleosin PF01277.17 PVD24896.1 - 0.045 13.5 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Oleosin PetL PF05115.14 PVD24896.1 - 0.22 11.5 1.5 0.42 10.6 1.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) VIT PF08487.10 PVD24897.1 - 1.2e-15 57.6 0.0 2.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 PVD24897.1 - 6.4e-07 29.8 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD24897.1 - 0.00013 22.0 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain 7tm_1 PF00001.21 PVD24898.1 - 1.7e-42 145.6 0.0 2.2e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD24898.1 - 1.3e-07 31.6 8.6 1.3e-07 31.6 8.6 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD24898.1 - 3.2e-05 23.5 1.5 3.2e-05 23.5 1.5 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 PVD24898.1 - 0.00064 19.2 14.5 0.13 11.6 0.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4663 PF15668.5 PVD24898.1 - 0.0043 16.2 0.2 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4663) 7tm_4 PF13853.6 PVD24898.1 - 0.0062 16.3 11.0 0.015 15.1 11.0 1.6 1 0 0 1 1 1 1 Olfactory receptor Renin_r PF07850.14 PVD24898.1 - 0.087 13.4 0.3 6.6 7.4 0.2 3.0 2 0 0 2 2 2 0 Renin receptor-like protein ResB PF05140.14 PVD24898.1 - 0.98 8.1 3.0 2.1 7.0 3.0 1.5 1 0 0 1 1 1 0 ResB-like family Serpentine_r_xa PF03383.15 PVD24898.1 - 3.6 7.5 9.7 2.4 8.1 6.3 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TUSC2 PF15000.6 PVD24899.1 - 5.4e-16 58.9 0.0 6.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Tumour suppressor candidate 2 MBOAT PF03062.19 PVD24900.1 - 7.8e-14 51.8 15.5 1.1e-13 51.2 15.4 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF4832 PF16116.5 PVD24901.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) Macoilin PF09726.9 PVD24902.1 - 0.00055 18.6 14.4 0.00055 18.6 14.4 1.7 2 0 0 2 2 2 1 Macoilin family RAP1 PF07218.11 PVD24902.1 - 0.061 11.6 10.1 0.1 10.9 10.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 PVD24902.1 - 0.19 11.1 2.8 0.36 10.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 PVD24902.1 - 0.24 11.5 16.4 0.12 12.4 13.2 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 PVD24902.1 - 0.72 9.9 13.8 2.1 8.4 13.8 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 PVD24902.1 - 3.3 8.4 12.0 6.1 7.6 0.8 2.7 1 1 1 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 PVD24902.1 - 8.4 5.9 9.5 16 4.9 9.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ESSS PF10183.9 PVD24903.1 - 7.9e-23 80.7 0.0 1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ThrE PF06738.12 PVD24903.1 - 0.18 11.1 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter Glyco_hydro_38N PF01074.22 PVD24905.1 - 4.6e-85 285.5 0.5 8.4e-85 284.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PVD24905.1 - 6.7e-59 199.5 0.0 1.1e-58 198.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PVD24905.1 - 5.3e-23 81.0 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PVD24905.1 - 7.3e-10 38.8 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_2_N PF02837.18 PVD24905.1 - 0.022 14.7 0.0 0.096 12.6 0.0 2.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain NDUF_B4 PF07225.12 PVD24906.1 - 2e-18 66.5 0.2 2.3e-18 66.3 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SPC12 PF06645.13 PVD24907.1 - 0.078 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PPC PF04151.15 PVD24907.1 - 3 9.0 8.6 12 7.1 0.4 3.9 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain RhoGEF PF00621.20 PVD24908.1 - 1.4e-15 58.0 2.5 1.6e-12 48.1 2.4 2.6 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 PVD24908.1 - 1.1e-10 41.6 0.1 2.9e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 PVD24908.1 - 0.00044 20.3 3.3 0.0037 17.4 0.2 3.5 4 0 0 4 4 4 1 Pleckstrin homology domain PH_16 PF17838.1 PVD24908.1 - 0.00078 19.3 2.2 0.0037 17.1 0.1 2.8 3 0 0 3 3 3 1 PH domain UPF0122 PF04297.14 PVD24908.1 - 0.013 15.7 0.2 0.04 14.1 0.2 1.8 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like PH_10 PF15411.6 PVD24908.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 PVD24908.1 - 0.06 13.3 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 PH domain IQCJ-SCHIP1 PF15157.6 PVD24908.1 - 0.083 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF4880 PF16220.5 PVD24908.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Mito_fiss_reg PF05308.11 PVD24909.1 - 0.27 11.3 1.3 0.28 11.2 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD24909.1 - 2.5 8.2 7.8 4 7.5 7.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD24909.1 - 3.7 6.9 6.7 4.4 6.7 6.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4691 PF15762.5 PVD24910.1 - 0.022 14.9 0.3 0.072 13.2 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4691) DUF3325 PF11804.8 PVD24910.1 - 0.052 13.7 1.2 0.052 13.7 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) CBM_14 PF01607.24 PVD24915.1 - 5.4e-48 161.0 62.5 2.1e-11 43.8 3.7 9.1 8 2 0 8 8 8 7 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD24916.1 - 6.3e-13 48.7 29.0 3.1e-06 27.3 0.7 5.5 3 2 1 5 5 5 4 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD24917.1 - 3.4e-47 158.4 80.1 4.4e-11 42.8 2.9 11.9 10 2 1 11 11 11 10 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD24918.1 - 2.3e-17 62.9 35.6 9.2e-06 25.7 3.2 5.6 5 0 0 5 5 5 4 Chitin binding Peritrophin-A domain Usp PF00582.26 PVD24919.1 - 1.5e-21 77.4 0.0 1.9e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Lectin_C PF00059.21 PVD24920.1 - 3.5e-14 53.4 0.3 6.3e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 PVD24920.1 - 0.026 14.5 1.0 0.026 14.5 1.0 2.0 2 0 0 2 2 2 0 PAN domain CRM1_repeat_3 PF18787.1 PVD24921.1 - 0.008 16.3 0.0 5.3 7.2 0.0 2.8 2 0 0 2 2 2 2 CRM1 / Exportin repeat 3 DUF1543 PF07566.12 PVD24921.1 - 0.061 13.1 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) GrpB PF04229.14 PVD24921.1 - 0.16 12.2 0.0 8.5 6.5 0.0 2.2 2 0 0 2 2 2 0 GrpB protein Sod_Fe_C PF02777.18 PVD24921.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Acyl-CoA_dh_1 PF00441.24 PVD24922.1 - 1.7e-10 41.3 0.1 4.7e-10 39.9 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PRIMA1 PF16101.5 PVD24922.1 - 0.04 14.0 2.2 0.077 13.0 2.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PAC1 PF16094.5 PVD24922.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 TPX2 PF06886.11 PVD24922.1 - 0.57 10.5 3.8 2.7 8.3 0.2 2.6 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) EGF PF00008.27 PVD24923.1 - 1.2e-38 131.0 136.3 8.9e-07 29.1 6.1 11.9 11 1 0 11 11 11 9 EGF-like domain DSL PF01414.19 PVD24923.1 - 5.5e-15 55.4 6.1 5.5e-15 55.4 6.1 8.6 4 1 5 9 9 9 2 Delta serrate ligand hEGF PF12661.7 PVD24923.1 - 2.7e-11 43.7 120.3 0.00034 21.1 4.9 13.1 13 1 0 13 13 13 7 Human growth factor-like EGF EGF_2 PF07974.13 PVD24923.1 - 0.025 15.0 4.1 0.025 15.0 4.1 12.0 12 0 0 12 12 12 0 EGF-like domain LapA_dom PF06305.11 PVD24923.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 PVD24923.1 - 0.2 12.5 3.9 0.42 11.5 0.0 3.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain BatA PF07584.11 PVD24923.1 - 0.28 11.6 0.1 0.53 10.7 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal SKG6 PF08693.10 PVD24923.1 - 8.6 5.9 7.7 15 5.1 7.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 PVD24924.1 - 2.7e-31 107.5 119.2 3.3e-05 24.1 10.0 9.7 10 0 0 10 10 10 8 EGF-like domain hEGF PF12661.7 PVD24924.1 - 8.9e-09 35.7 89.3 0.0089 16.6 7.0 10.2 9 1 1 10 10 10 7 Human growth factor-like EGF DSL PF01414.19 PVD24924.1 - 4.5e-08 33.3 1.9 4.5e-08 33.3 1.9 8.9 4 1 6 10 10 10 1 Delta serrate ligand ALMS_repeat PF18727.1 PVD24924.1 - 0.058 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Alstrom syndrome repeat Myc_target_1 PF15179.6 PVD24924.1 - 0.1 12.5 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Myc target protein 1 Caveolin PF01146.17 PVD24925.1 - 1.3e-34 119.0 0.7 1.4e-34 118.9 0.7 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 PVD24926.1 - 6.1e-35 120.1 0.6 7.2e-35 119.8 0.6 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 PVD24927.1 - 1.8e-43 147.7 0.2 2.2e-43 147.4 0.2 1.0 1 0 0 1 1 1 1 Caveolin MACPF PF01823.19 PVD24928.1 - 4.6e-16 59.5 0.0 8.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Kelch_4 PF13418.6 PVD24928.1 - 0.012 15.6 0.4 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF4690 PF15756.5 PVD24928.1 - 0.072 13.7 0.2 0.072 13.7 0.2 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage LRR_6 PF13516.6 PVD24929.1 - 3.4e-21 73.4 13.3 2.8e-05 23.8 0.1 6.0 5 1 1 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 PVD24929.1 - 2e-07 30.6 2.2 4.1 8.3 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat EF-hand_6 PF13405.6 PVD24929.1 - 0.00014 21.5 0.0 0.00061 19.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PVD24929.1 - 0.00049 19.4 0.0 0.0016 17.8 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 PVD24929.1 - 0.0082 15.6 0.8 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD24929.1 - 0.04 14.4 0.0 0.17 12.4 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair LRR_8 PF13855.6 PVD24929.1 - 0.065 13.0 9.5 3.7 7.4 0.0 4.5 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 PVD24929.1 - 0.098 13.1 0.5 0.098 13.1 0.5 3.8 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) HlyIII PF03006.20 PVD24930.1 - 1.4e-72 244.0 22.2 1.7e-72 243.8 22.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related CopD PF05425.13 PVD24930.1 - 0.0089 16.4 0.9 0.0089 16.4 0.9 2.6 3 0 0 3 3 3 1 Copper resistance protein D DUF4131 PF13567.6 PVD24930.1 - 9.5 5.8 15.6 0.37 10.4 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Ras PF00071.22 PVD24931.1 - 1.3e-42 145.1 0.0 1.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24931.1 - 2.3e-28 98.8 0.0 3.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24931.1 - 3.5e-13 49.4 0.0 4.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD24931.1 - 1.7e-05 24.9 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD24931.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD24931.1 - 0.0018 17.8 0.0 0.14 11.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 PVD24931.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 PVD24931.1 - 0.065 12.7 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region P3A PF08727.11 PVD24931.1 - 0.074 12.5 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like SRPRB PF09439.10 PVD24931.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Exo_endo_phos_2 PF14529.6 PVD24931.1 - 0.14 12.0 0.1 0.62 9.9 0.0 2.1 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Ras PF00071.22 PVD24932.1 - 5.1e-16 58.7 0.3 6.2e-16 58.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD24932.1 - 9.3e-16 58.1 0.5 1.2e-15 57.8 0.5 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24932.1 - 2.9e-05 23.6 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD24932.1 - 0.0038 17.3 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PVD24932.1 - 0.012 15.3 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PVD24932.1 - 0.027 13.9 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 PVD24932.1 - 0.044 13.1 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 PVD24932.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PVD24932.1 - 0.16 12.4 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain tRNA-synt_1 PF00133.22 PVD24936.1 - 5.3e-233 774.7 0.1 7.5e-233 774.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PVD24936.1 - 1.8e-23 83.2 0.0 7.3e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PVD24936.1 - 3.6e-13 49.0 0.5 0.0013 17.6 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PVD24936.1 - 0.12 11.7 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain CortBP2 PF09727.9 PVD24937.1 - 9.3e-74 247.5 17.1 9.3e-74 247.5 17.1 2.1 2 0 0 2 2 2 2 Cortactin-binding protein-2 DUF3037 PF11236.8 PVD24937.1 - 4.5 7.7 10.2 5.7 7.4 5.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) betaPIX_CC PF16523.5 PVD24937.1 - 4.8 7.1 23.8 0.21 11.4 2.7 3.7 3 1 1 4 4 4 0 betaPIX coiled coil Ank_2 PF12796.7 PVD24938.1 - 1.9e-23 82.9 6.4 1.1e-12 48.4 0.4 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD24938.1 - 5.8e-22 77.8 1.2 1.7e-07 31.6 0.0 5.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD24938.1 - 3.1e-15 56.0 2.5 2e-06 28.0 0.0 4.8 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD24938.1 - 1.1e-14 53.0 6.4 0.002 18.5 0.0 6.7 5 1 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PVD24938.1 - 9.5e-10 38.5 22.4 0.0052 17.2 0.1 6.8 7 1 0 7 7 7 4 Ankyrin repeat AAA_22 PF13401.6 PVD24938.1 - 0.00058 20.2 0.2 0.0082 16.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 PVD24938.1 - 0.045 14.2 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Secretin PF00263.21 PVD24939.1 - 0.015 14.9 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Pkinase PF00069.25 PVD24940.1 - 6e-48 163.5 0.1 8.8e-48 163.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24940.1 - 1.7e-34 119.3 0.1 2.5e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD24940.1 - 8.6e-06 24.8 0.0 1.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase PBD PF00786.28 PVD24940.1 - 0.0005 20.4 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 PVD24940.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PVD24940.1 - 0.097 12.6 0.1 0.69 9.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 PVD24940.1 - 0.14 11.7 0.0 2.5 7.6 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GRDP-like PF07173.12 PVD24942.1 - 4.3e-50 170.1 4.3 2.1e-41 141.9 1.0 3.1 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like WW PF00397.26 PVD24943.1 - 0.22 11.6 2.6 0.72 10.0 2.6 1.9 1 1 0 1 1 1 0 WW domain SH2 PF00017.24 PVD24944.1 - 5.1e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 PVD24944.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Ank_2 PF12796.7 PVD24945.1 - 5.6e-10 39.7 0.0 1.4e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD24945.1 - 1.1e-08 35.2 0.0 3.3e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD24945.1 - 1.2e-05 25.7 0.0 6.9e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD24945.1 - 2.9e-05 24.3 0.1 0.00014 22.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 PVD24945.1 - 0.0002 21.5 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat ADIP PF11559.8 PVD24945.1 - 0.0026 17.9 15.4 0.0026 17.9 15.4 3.5 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding MHC_I_2 PF14586.6 PVD24945.1 - 0.038 13.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 CCDC144C PF14915.6 PVD24946.1 - 5.6e-38 130.8 52.4 5.6e-38 130.8 52.4 4.9 1 1 3 5 5 5 2 CCDC144C protein coiled-coil region Fez1 PF06818.15 PVD24946.1 - 0.0015 19.0 19.2 0.0015 19.0 19.2 5.9 1 1 4 5 5 5 1 Fez1 Tho2 PF11262.8 PVD24946.1 - 0.0068 15.7 4.1 0.0068 15.7 4.1 6.7 3 3 4 7 7 7 1 Transcription factor/nuclear export subunit protein 2 Nup54_57_C PF18570.1 PVD24946.1 - 0.023 14.3 0.5 0.023 14.3 0.5 3.3 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain TK PF00265.18 PVD24946.1 - 1.5 8.7 5.6 0.71 9.7 1.7 2.5 2 2 2 4 4 4 0 Thymidine kinase HMMR_N PF15905.5 PVD24946.1 - 3.6 7.0 112.0 2.8 7.3 19.1 5.2 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor N-terminal PapC_N PF13954.6 PVD24946.1 - 9.9 6.2 12.0 3.2 7.8 0.6 4.1 4 0 0 4 4 4 0 PapC N-terminal domain Ras PF00071.22 PVD24947.1 - 1.1e-39 135.7 0.2 4.8e-39 133.6 0.2 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD24947.1 - 2.2e-27 95.7 0.1 3.3e-26 91.8 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD24947.1 - 2.7e-11 43.3 0.1 2.6e-10 40.1 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD24947.1 - 0.00029 20.5 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD24947.1 - 0.0005 20.1 0.0 0.00098 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD24947.1 - 0.0012 18.2 0.1 0.0028 17.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PVD24947.1 - 0.0018 18.1 0.1 0.27 11.0 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF1580 PF07618.11 PVD24947.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) CARD PF00619.21 PVD24948.1 - 1.5e-12 47.3 0.9 1.9e-12 47.0 0.9 1.1 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD24948.1 - 2.2e-06 27.6 0.2 2.9e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Caspase recruitment domain Retrotran_gag_2 PF14223.6 PVD24948.1 - 0.042 13.5 1.0 0.051 13.2 1.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ribosomal_L19 PF01245.20 PVD24948.1 - 0.06 13.3 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L19 Ank_2 PF12796.7 PVD24949.1 - 5.9e-29 100.5 6.5 3.2e-12 46.9 1.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD24949.1 - 1.8e-26 89.2 3.3 3.1e-05 24.0 0.1 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 PVD24949.1 - 6e-26 90.5 2.0 7.2e-10 39.2 0.5 4.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD24949.1 - 5.2e-25 86.8 3.5 2.3e-06 27.8 0.6 6.8 5 1 1 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 PVD24949.1 - 5.9e-19 67.9 6.7 2.3e-10 40.5 0.9 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 PVD24949.1 - 2.1e-11 44.0 0.0 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain UbiA PF01040.18 PVD24950.1 - 3.8e-53 180.4 14.2 4.7e-53 180.1 14.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 PVD24950.1 - 0.0013 18.5 0.6 0.0013 18.5 0.6 3.2 3 0 0 3 3 3 1 Oligosaccaryltransferase Sipho_Gp37 PF14594.6 PVD24951.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein MBD PF01429.19 PVD24952.1 - 1.4e-11 43.9 0.1 4.4e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain AT_hook PF02178.19 PVD24952.1 - 1.9 8.6 10.6 0.076 12.9 3.7 2.6 2 0 0 2 2 2 0 AT hook motif YABBY PF04690.13 PVD24952.1 - 7.6 7.1 9.0 3.5 8.2 0.3 3.3 2 1 0 2 2 2 0 YABBY protein WD40 PF00400.32 PVD24953.1 - 3.5e-11 43.5 11.6 0.056 14.3 0.4 7.9 7 1 1 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD24953.1 - 4.5e-10 39.7 0.1 0.03 14.6 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD24953.1 - 6.8e-05 22.3 0.3 0.01 15.2 0.4 2.2 1 1 1 2 2 2 2 WD40-like domain Apolipoprotein PF01442.18 PVD24954.1 - 0.034 14.0 1.4 0.15 11.9 1.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1048 PF06304.11 PVD24954.1 - 0.047 14.1 1.7 0.88 10.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1048) Sipho_Gp157 PF05565.11 PVD24954.1 - 0.078 13.0 1.0 0.2 11.7 1.0 1.7 1 1 0 1 1 1 0 Siphovirus Gp157 bZIP_2 PF07716.15 PVD24954.1 - 0.3 11.2 4.4 0.67 10.1 0.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF848 PF05852.11 PVD24954.1 - 1.1 9.3 4.2 16 5.5 0.2 3.0 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Ank_3 PF13606.6 PVD24955.1 - 0.00017 21.8 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PVD24955.1 - 0.066 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD24955.1 - 0.13 12.6 0.1 0.6 10.5 0.1 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Mgr1 PF08602.10 PVD24955.1 - 0.45 9.3 2.5 0.86 8.4 2.5 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit 7tm_1 PF00001.21 PVD24956.1 - 2.2e-19 69.8 2.6 2.7e-19 69.5 2.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD24956.1 - 0.0019 17.6 3.3 0.007 15.8 3.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4212 PF13937.6 PVD24956.1 - 0.045 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF5357 PF17310.2 PVD24956.1 - 0.32 9.5 2.4 0.53 8.8 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Pkinase PF00069.25 PVD24957.1 - 2.3e-68 230.4 0.0 3.6e-68 229.8 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24957.1 - 6.2e-28 97.8 0.0 7.8e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD24957.1 - 0.0022 17.0 0.0 0.0044 16.0 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD24957.1 - 0.031 13.6 0.2 0.16 11.3 0.0 2.1 2 1 1 3 3 3 0 Kinase-like APH PF01636.23 PVD24957.1 - 0.08 12.9 0.0 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD24957.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 PVD24957.1 - 0.2 10.6 0.1 0.36 9.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 PVD24959.1 - 4.3e-30 104.9 0.0 8.4e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD24959.1 - 2.4e-29 102.5 0.0 5.4e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Dynamin_N PF00350.23 PVD24959.1 - 2.5e-15 57.0 0.1 9.5e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PVD24959.1 - 1e-05 25.6 0.0 3.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24959.1 - 5.3e-05 23.2 0.1 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PVD24959.1 - 0.00066 20.2 0.4 0.0031 18.0 0.0 2.3 2 1 0 2 2 2 1 ABC transporter DUF659 PF04937.15 PVD24959.1 - 0.0042 17.0 0.1 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) AAA_29 PF13555.6 PVD24959.1 - 0.0076 16.0 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC1 PF03109.16 PVD24959.1 - 0.01 16.0 1.4 0.053 13.7 0.0 3.0 4 0 0 4 4 4 0 ABC1 family T2SSE PF00437.20 PVD24959.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 PVD24959.1 - 0.058 12.7 0.0 0.26 10.6 0.0 2.1 1 0 0 1 1 1 0 Zeta toxin AIG1 PF04548.16 PVD24959.1 - 0.16 11.3 0.4 2.1 7.6 0.2 2.7 2 1 1 3 3 3 0 AIG1 family AAA_23 PF13476.6 PVD24959.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.6 2 1 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 PVD24960.1 - 6.5e-19 68.6 0.0 1.9e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PVD24960.1 - 2.8e-07 30.6 0.0 9.5e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD24960.1 - 0.00095 19.1 0.9 0.0088 16.0 0.2 2.4 2 1 1 3 3 3 1 RsgA GTPase T2SSE PF00437.20 PVD24960.1 - 0.0015 17.7 0.3 0.0032 16.6 0.3 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein GTP_EFTU PF00009.27 PVD24960.1 - 0.0027 17.3 0.5 1.9 8.0 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PVD24960.1 - 0.011 16.2 0.0 0.03 14.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 PVD24960.1 - 0.014 14.8 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 PVD24960.1 - 0.017 14.0 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) IIGP PF05049.13 PVD24960.1 - 0.023 13.8 0.1 0.066 12.3 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 PVD24960.1 - 0.03 13.8 0.1 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF148 PF02520.17 PVD24960.1 - 0.052 13.7 0.5 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 FtsK_SpoIIIE PF01580.18 PVD24960.1 - 0.065 12.6 0.1 0.16 11.3 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 PVD24960.1 - 0.091 13.1 0.2 0.23 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PVD24960.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 PVD24961.1 - 1.9e-05 24.1 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD24961.1 - 0.00058 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LLC1 PF14945.6 PVD24961.1 - 0.04 14.5 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein GlutR_N PF05201.15 PVD24961.1 - 0.12 12.1 0.1 0.89 9.3 0.0 2.5 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain Fibrinogen_C PF00147.18 PVD24962.1 - 4.3e-09 36.5 0.2 6.4e-09 35.9 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD24962.1 - 8.8e-05 22.4 1.3 0.0002 21.2 1.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD24962.1 - 0.015 15.2 1.0 0.043 13.7 1.0 1.7 1 0 0 1 1 1 0 PAN domain Fibrinogen_C PF00147.18 PVD24963.1 - 9.8e-37 126.9 0.3 1.3e-36 126.4 0.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD24963.1 - 2.5e-06 27.3 3.5 5.9e-06 26.2 3.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD24963.1 - 0.003 17.4 1.0 0.014 15.3 1.0 2.2 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 PVD24963.1 - 0.0061 16.3 0.3 0.0061 16.3 0.3 2.2 2 0 0 2 2 2 1 PAN-like domain hEGF PF12661.7 PVD24963.1 - 0.043 14.4 5.0 0.043 14.4 5.0 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 PVD24963.1 - 0.044 14.2 4.3 0.044 14.2 4.3 2.9 3 0 0 3 3 3 0 EGF-like domain Fibrinogen_C PF00147.18 PVD24964.1 - 1.2e-34 120.0 0.3 1.7e-34 119.6 0.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD24964.1 - 0.0036 17.2 2.4 0.0081 16.1 2.4 1.6 1 0 0 1 1 1 1 PAN domain hEGF PF12661.7 PVD24964.1 - 0.013 16.1 4.4 0.017 15.7 2.0 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Fibrinogen_C PF00147.18 PVD24965.1 - 1.5e-14 54.4 0.0 2.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain UPF0126 PF03458.13 PVD24965.1 - 0.14 12.1 0.7 0.25 11.2 0.7 1.4 1 0 0 1 1 1 0 UPF0126 domain RIBIOP_C PF04950.12 PVD24966.1 - 3.1e-90 302.6 0.2 3.1e-90 302.6 0.2 2.7 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PVD24966.1 - 3.5e-34 116.7 1.3 1.2e-33 115.0 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 PVD24966.1 - 9.8e-07 28.5 0.0 0.00042 19.9 0.0 3.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD24966.1 - 0.0015 18.6 0.6 0.077 13.1 0.2 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 PVD24966.1 - 0.016 15.7 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PVD24966.1 - 0.039 14.3 0.0 0.87 10.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 PVD24966.1 - 0.067 12.7 0.1 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 PVD24966.1 - 0.077 12.7 0.1 0.32 10.7 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PVD24966.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.4 3 0 0 3 3 3 0 ABC transporter Cadherin PF00028.17 PVD24967.1 - 3.3e-09 37.1 0.1 0.00015 22.1 0.0 3.0 2 1 0 2 2 2 2 Cadherin domain DUF3138 PF11336.8 PVD24967.1 - 0.032 12.9 0.0 0.06 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) 7tm_2 PF00002.24 PVD24968.1 - 2.4e-28 99.1 11.1 2.7e-22 79.2 3.0 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) EGF PF00008.27 PVD24968.1 - 8e-16 58.0 136.8 0.00011 22.5 7.0 11.1 11 0 0 11 11 11 9 EGF-like domain EGF_2 PF07974.13 PVD24968.1 - 2.7e-07 30.8 137.1 0.008 16.5 7.0 10.9 10 1 0 10 10 10 8 EGF-like domain EGF_3 PF12947.7 PVD24968.1 - 0.0099 16.1 4.4 0.0099 16.1 4.4 10.4 9 1 0 9 9 9 5 EGF domain hEGF PF12661.7 PVD24968.1 - 0.011 16.3 5.7 0.011 16.3 5.7 11.7 10 2 0 10 10 10 0 Human growth factor-like EGF Arabino_trans_C PF14896.6 PVD24969.1 - 3 6.8 8.8 0.44 9.5 1.5 2.0 1 1 0 2 2 2 0 EmbC C-terminal domain 7tm_2 PF00002.24 PVD24970.1 - 1.4e-49 168.6 16.1 2e-49 168.1 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EGF PF00008.27 PVD24970.1 - 6.3e-17 61.6 109.4 1.8e-06 28.1 10.6 9.2 7 1 2 9 9 9 6 EGF-like domain GPS PF01825.21 PVD24970.1 - 1.7e-13 50.8 2.3 1.7e-13 50.8 2.3 4.9 6 0 0 6 6 6 1 GPCR proteolysis site, GPS, motif EGF_2 PF07974.13 PVD24970.1 - 1.2e-07 31.9 112.9 0.021 15.2 12.3 8.6 8 0 0 8 8 8 7 EGF-like domain Frizzled PF01534.17 PVD24970.1 - 9.9e-06 24.8 10.6 9.9e-06 24.8 10.6 2.0 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region EGF_3 PF12947.7 PVD24970.1 - 0.0002 21.5 26.9 0.0011 19.1 14.2 8.3 6 2 2 8 8 8 4 EGF domain hEGF PF12661.7 PVD24970.1 - 0.0044 17.6 97.3 0.0063 17.1 11.2 9.4 8 0 0 8 8 8 5 Human growth factor-like EGF Cadherin PF00028.17 PVD24971.1 - 0.011 16.1 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Cadherin domain GW PF13457.6 PVD24971.1 - 0.02 15.5 0.1 0.026 15.1 0.1 1.1 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain Gly_acyl_tr_N PF06021.11 PVD24973.1 - 2.3e-16 60.5 0.0 8.4e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase FR47 PF08445.10 PVD24973.1 - 9.7e-10 38.3 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 PVD24973.1 - 5.7e-06 26.6 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD24973.1 - 0.00026 20.9 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PVD24973.1 - 0.00061 20.5 0.0 0.9 10.2 0.0 2.4 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 PVD24973.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.7 PVD24973.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hist_deacetyl PF00850.19 PVD24974.1 - 8.5e-73 245.5 0.8 4.5e-72 243.1 0.0 2.4 4 0 0 4 4 4 1 Histone deacetylase domain IBR PF01485.21 PVD24974.1 - 4.1e-16 59.0 45.8 2.9e-11 43.4 8.1 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 PVD24974.1 - 0.00011 22.1 4.9 0.00011 22.1 4.9 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD24974.1 - 0.00029 20.7 4.1 0.00029 20.7 4.1 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD24974.1 - 0.00033 20.6 5.9 0.00033 20.6 5.9 4.6 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD24974.1 - 0.00081 19.7 4.7 0.00081 19.7 4.7 4.5 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD24974.1 - 0.002 17.9 5.4 0.002 17.9 5.4 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PROCT PF08084.11 PVD24974.1 - 2.2 8.2 4.3 0.59 10.1 0.2 2.1 2 0 0 2 2 2 0 PROCT (NUC072) domain AAA_12 PF13087.6 PVD24975.1 - 3.7e-46 157.3 0.0 1e-45 155.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PVD24975.1 - 4.4e-30 105.3 0.1 2.7e-15 56.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain S1-like PF14444.6 PVD24975.1 - 7.9e-24 83.4 0.1 1.6e-08 34.3 0.1 3.8 3 0 0 3 3 3 3 S1-like AAA_30 PF13604.6 PVD24975.1 - 7.5e-12 45.4 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD24975.1 - 1.5e-07 31.9 0.0 7.2e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 PVD24975.1 - 0.00041 20.0 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 PVD24975.1 - 0.0045 17.0 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 PVD24975.1 - 0.0089 15.5 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein PIF1 PF05970.14 PVD24975.1 - 0.042 13.0 0.2 8.3 5.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.14 PVD24975.1 - 0.095 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD24975.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD24975.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_N PF16745.5 PVD24975.1 - 0.11 12.2 0.7 17 5.2 0.1 2.9 2 0 0 2 2 2 0 RsgA N-terminal domain UvrD_C_2 PF13538.6 PVD24975.1 - 0.12 12.3 0.9 1 9.3 0.9 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain VWA PF00092.28 PVD24976.1 - 2.5e-05 24.6 0.0 4.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain WASH_WAHD PF11945.8 PVD24977.1 - 4.1e-93 312.1 0.1 6.1e-93 311.5 0.1 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 PVD24977.1 - 0.48 10.3 6.5 0.093 12.6 1.8 2.4 2 1 0 2 2 2 0 WH2 motif Peptidase_M24 PF00557.24 PVD24978.1 - 5.3e-42 143.9 0.1 6.9e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_polI_A34 PF08208.11 PVD24978.1 - 0.1 12.7 19.2 0.18 11.9 19.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 PVD24978.1 - 0.16 12.1 16.0 0.23 11.5 16.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Med19 PF10278.9 PVD24978.1 - 0.29 11.1 14.7 0.66 9.9 14.4 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 PVD24978.1 - 0.42 10.2 17.2 0.056 13.0 12.5 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.6 PVD24978.1 - 0.75 9.5 6.3 1.3 8.8 6.3 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 PVD24978.1 - 1.9 6.7 10.6 2.8 6.1 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PcfK PF14058.6 PVD24978.1 - 2 8.7 16.8 14 6.0 0.1 2.4 2 0 0 2 2 2 0 PcfK-like protein Presenilin PF01080.17 PVD24978.1 - 7.4 5.2 6.6 10 4.8 6.6 1.1 1 0 0 1 1 1 0 Presenilin OCRE PF17780.1 PVD24979.1 - 2.9e-18 65.6 17.4 2.9e-18 65.6 17.4 2.8 3 0 0 3 3 3 1 OCRE domain G-patch PF01585.23 PVD24979.1 - 3.4e-17 62.1 1.2 3.4e-17 62.1 1.2 1.9 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 PVD24979.1 - 9.8e-12 44.5 0.0 3.6e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 PVD24979.1 - 5e-10 39.3 3.4 5e-10 39.3 3.4 3.0 2 1 1 3 3 3 1 G-patch domain ABC2_membrane_3 PF12698.7 PVD24979.1 - 4.9 6.1 9.0 8 5.5 9.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SSF PF00474.17 PVD24980.1 - 1.1e-24 87.1 19.0 6.8e-17 61.4 1.1 3.3 2 1 2 4 4 4 2 Sodium:solute symporter family Cadherin PF00028.17 PVD24982.1 - 2.6e-07 31.0 0.0 7.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Cadherin domain F5_F8_type_C PF00754.25 PVD24984.1 - 0.00023 21.3 1.1 0.001 19.2 0.0 2.5 3 0 0 3 3 3 1 F5/8 type C domain DUF4551 PF15087.6 PVD24985.1 - 7.7e-98 328.9 0.1 3.7e-88 296.9 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4551) Aminotran_1_2 PF00155.21 PVD24986.1 - 8.2e-70 235.8 0.0 1.1e-69 235.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PVD24986.1 - 7.2e-08 31.4 0.0 1.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PVD24986.1 - 3e-06 26.4 0.0 7.2e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PVD24986.1 - 6.3e-05 22.4 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PVD24986.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fibrinogen_aC PF12160.8 PVD24986.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha C domain Apis_Csd PF11671.8 PVD24986.1 - 0.22 11.6 1.2 0.39 10.7 1.2 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Laminin_EGF PF00053.24 PVD24987.1 - 3e-97 318.6 238.0 7.4e-12 45.2 12.9 13.2 12 1 1 13 13 13 12 Laminin EGF domain Laminin_N PF00055.17 PVD24987.1 - 2.6e-61 207.2 6.5 6.9e-61 205.8 0.2 3.5 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_II PF06009.12 PVD24987.1 - 0.0041 17.1 2.0 0.0041 17.1 2.0 6.9 2 2 5 7 7 7 2 Laminin Domain II F5_F8_type_C PF00754.25 PVD24987.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Fib_alpha PF08702.10 PVD24987.1 - 0.2 11.8 43.3 0.11 12.7 2.6 5.5 2 2 4 6 6 6 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 PVD24987.1 - 3.9 7.5 37.9 4.3 7.4 2.1 6.6 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 PVD24987.1 - 4.7 7.1 16.5 0.072 13.0 0.4 4.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain PUB PF09409.10 PVD24988.1 - 6.5e-26 90.1 0.4 1.3e-25 89.1 0.4 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 PVD24988.1 - 1.3e-06 28.5 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain Metallophos PF00149.28 PVD24989.1 - 1.5e-18 68.0 1.2 3e-18 67.1 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PVD24989.1 - 2.3e-11 44.4 0.1 4.8e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PVD24989.1 - 4.8e-05 23.8 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 PVD24989.1 - 0.00068 19.9 0.0 0.0024 18.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 PVD24989.1 - 0.21 12.1 0.6 0.82 10.2 0.0 2.2 3 0 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain UDG PF03167.19 PVD24990.1 - 2.3e-15 56.9 0.0 8.2e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily BHD_3 PF10405.9 PVD24991.1 - 2.8e-24 85.3 0.0 5.7e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 PVD24991.1 - 4.2e-13 50.0 0.5 4.2e-13 50.0 0.5 5.7 6 2 0 6 6 6 1 Rad4 beta-hairpin domain 2 IN_DBD_C PF00552.21 PVD24992.1 - 0.24 10.7 3.7 9.7 5.6 0.1 3.2 3 0 0 3 3 3 0 Integrase DNA binding domain Synaptonemal_3 PF15191.6 PVD24992.1 - 0.59 9.9 7.0 11 5.8 1.1 4.0 2 1 2 4 4 4 0 Synaptonemal complex central element protein 3 DUF2374 PF09574.10 PVD24992.1 - 4.3 7.2 8.9 8.9 6.2 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) Baculo_LEF-10 PF07206.11 PVD24993.1 - 0.32 11.2 3.9 12 6.2 0.0 3.4 2 1 2 4 4 4 0 Baculovirus late expression factor 10 (LEF-10) Synaptonemal_3 PF15191.6 PVD24993.1 - 2.4 8.0 3.9 24 4.8 0.8 3.0 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Pkinase_Tyr PF07714.17 PVD24994.1 - 4.9e-57 193.2 0.8 8.1e-46 156.4 0.0 3.5 1 1 2 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PVD24994.1 - 1.7e-22 80.1 0.1 1.3e-20 73.9 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PVD24994.1 - 0.012 15.0 0.0 0.052 12.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like TonB_N PF16031.5 PVD24994.1 - 0.014 15.9 4.1 0.025 15.1 4.1 1.3 1 0 0 1 1 1 0 TonB polyproline region EphA2_TM PF14575.6 PVD24994.1 - 0.11 13.4 0.6 0.89 10.5 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 PVD24994.1 - 0.13 12.2 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 IBD PF10416.9 PVD24995.1 - 0.087 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Sema PF01403.19 PVD24996.1 - 3.4e-08 32.8 1.2 5.7e-08 32.0 1.2 1.5 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 PVD24996.1 - 1.4e-07 31.4 9.0 0.00032 20.7 1.5 4.4 4 0 0 4 4 4 2 IPT/TIG domain LAT PF15234.6 PVD24997.1 - 0.042 13.6 5.1 0.064 13.0 5.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF1397 PF07165.11 PVD24999.1 - 0.0048 16.3 2.4 0.0066 15.9 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) Pet191_N PF10203.9 PVD24999.1 - 0.23 11.8 3.8 0.14 12.5 1.3 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 AAA_6 PF12774.7 PVD25000.1 - 2.9e-149 496.5 0.1 1.8e-148 493.9 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD25000.1 - 1.3e-136 455.9 8.5 1.3e-136 455.9 8.5 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD25000.1 - 8.8e-108 360.1 0.7 5.6e-107 357.5 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD25000.1 - 5.5e-91 303.6 0.6 5.5e-91 303.6 0.6 2.6 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD25000.1 - 1.1e-78 263.0 0.1 3.1e-76 254.9 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 PVD25000.1 - 1.7e-65 221.0 0.1 1.7e-47 162.0 0.0 3.0 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 PVD25000.1 - 6.2e-65 218.0 0.1 3.2e-64 215.7 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD25000.1 - 9.6e-51 172.8 6.7 2.2e-50 171.6 6.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD25000.1 - 1.1e-45 154.6 0.0 1.1e-43 148.1 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD25000.1 - 9e-23 80.8 0.1 6.4e-22 78.0 0.1 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD25000.1 - 2.2e-18 66.6 0.0 1.4e-07 31.6 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD25000.1 - 7.9e-17 61.3 1.4 4.7e-16 58.8 1.1 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 PVD25000.1 - 7e-06 26.5 0.4 0.35 11.3 0.1 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD25000.1 - 0.0042 17.5 0.1 4.1 7.8 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 PVD25000.1 - 0.0048 17.2 0.0 4.8 7.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PVD25000.1 - 0.0055 17.2 0.0 0.097 13.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 PVD25000.1 - 0.022 15.1 0.0 11 6.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase rve_3 PF13683.6 PVD25000.1 - 0.058 13.2 0.2 0.71 9.7 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain Sigma54_activat PF00158.26 PVD25000.1 - 0.075 12.7 0.2 0.37 10.5 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 PVD25000.1 - 0.13 12.4 0.2 17 5.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.11 PVD25000.1 - 7 6.8 18.0 2 8.6 6.0 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) An_peroxidase PF03098.15 PVD25001.1 - 4.7e-95 319.2 0.0 8.3e-64 216.1 0.0 3.5 1 1 3 4 4 4 3 Animal haem peroxidase DUF1936 PF09151.10 PVD25001.1 - 0.073 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Lectin_C PF00059.21 PVD25002.1 - 1.5e-09 38.5 1.7 2.7e-09 37.7 1.7 1.4 1 0 0 1 1 1 1 Lectin C-type domain MFS_1 PF07690.16 PVD25003.1 - 6.5e-45 153.6 50.4 2.3e-42 145.2 37.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD25003.1 - 0.003 16.2 33.4 0.016 13.8 20.7 3.5 1 1 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.21 PVD25003.1 - 0.0043 15.9 4.3 0.0043 15.9 4.3 3.1 3 0 0 3 3 3 1 POT family YlaH PF14036.6 PVD25003.1 - 0.094 13.0 4.4 5.6 7.4 0.3 2.9 2 0 0 2 2 2 0 YlaH-like protein OATP PF03137.20 PVD25003.1 - 0.11 10.8 13.4 8.8 4.5 12.2 2.8 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_1 PF00583.25 PVD25004.1 - 2e-15 57.1 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD25004.1 - 6.1e-10 39.1 0.1 7.8e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD25004.1 - 4.9e-09 36.5 0.0 7.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PVD25004.1 - 3.9e-07 29.9 0.0 6.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PVD25004.1 - 0.00043 20.4 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 PVD25004.1 - 0.0056 16.6 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 PVD25004.1 - 0.011 15.3 0.2 0.018 14.5 0.2 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 PVD25004.1 - 0.021 15.5 0.0 0.033 14.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 PVD25004.1 - 0.036 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ CD34_antigen PF06365.12 PVD25005.1 - 0.035 13.7 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 CD34/Podocalyxin family TUDOR PF00567.24 PVD25006.1 - 7.1e-22 77.7 0.0 8.3e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 PVD25006.1 - 0.0012 19.3 0.3 0.0022 18.4 0.3 1.5 1 0 0 1 1 1 1 Agenet domain TUDOR PF00567.24 PVD25009.1 - 4.7e-17 62.1 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Tudor domain DUF727 PF05303.12 PVD25009.1 - 0.038 14.0 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Vezatin PF12632.7 PVD25010.1 - 4.7e-07 29.5 11.6 0.00023 20.6 0.4 3.3 2 1 1 3 3 3 2 Mysoin-binding motif of peroxisomes FAP206 PF12018.8 PVD25010.1 - 0.021 14.4 1.0 0.021 14.4 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF4835 PF16119.5 PVD25010.1 - 0.046 12.8 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) RepL PF05732.11 PVD25010.1 - 0.053 12.9 0.7 0.25 10.8 0.1 2.2 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) PMC2NT PF08066.12 PVD25010.1 - 0.32 11.7 2.1 4.4 8.1 0.0 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Phage_sheath_1C PF17482.2 PVD25011.1 - 0.033 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain ABC2_membrane_3 PF12698.7 PVD25012.1 - 7.6e-57 193.0 53.9 2.4e-40 138.7 20.7 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 PVD25012.1 - 1.7e-32 112.8 0.0 1e-22 81.1 0.0 2.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 PVD25012.1 - 5.8e-19 69.0 0.0 3.4e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PVD25012.1 - 0.00011 21.7 36.8 0.00094 18.7 11.6 4.6 6 0 0 6 6 6 2 ABC-2 type transporter SbcCD_C PF13558.6 PVD25012.1 - 0.00016 21.8 0.0 0.23 11.7 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 PVD25012.1 - 0.00022 20.8 0.0 0.29 10.5 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Acetyltransf_17 PF17668.1 PVD25012.1 - 0.055 14.3 0.1 0.99 10.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_23 PF13476.6 PVD25012.1 - 0.14 12.6 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_3 PF01171.20 PVD25012.1 - 0.19 11.5 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 PP-loop family ABC_tran PF00005.27 PVD25013.1 - 2.3e-23 83.2 0.0 3.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PVD25013.1 - 3.1e-08 33.1 12.5 3.1e-08 33.1 12.5 3.2 1 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 PVD25013.1 - 2.5e-06 27.5 0.5 0.0072 16.2 0.0 2.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PVD25013.1 - 0.0097 16.4 0.8 0.017 15.6 0.8 1.3 1 0 0 1 1 1 1 AAA domain MukB PF04310.12 PVD25013.1 - 0.025 14.4 0.3 0.047 13.5 0.3 1.4 1 0 0 1 1 1 0 MukB N-terminal SMC_N PF02463.19 PVD25013.1 - 0.027 13.9 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PVD25013.1 - 0.047 13.4 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 PVD25013.1 - 0.054 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 PVD25013.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD25013.1 - 0.18 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PVD25013.1 - 0.24 11.2 3.4 0.14 12.0 0.3 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane PF01061.24 PVD25013.1 - 1.9 7.8 28.7 1 8.8 14.5 3.3 2 1 0 3 3 3 0 ABC-2 type transporter ABC2_membrane_4 PF12730.7 PVD25013.1 - 9.6 6.1 15.8 14 5.6 0.1 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 PVD25014.1 - 1e-29 103.8 16.7 2.7e-29 102.4 16.7 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 PVD25014.1 - 1.6e-05 25.4 0.0 3.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 PVD25014.1 - 0.15 12.5 0.2 0.37 11.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 PVD25015.1 - 3.7e-08 33.5 0.0 5.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 PVD25015.1 - 0.0013 19.2 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter UDPGT PF00201.18 PVD25016.1 - 5.6e-71 239.8 0.0 1.1e-70 238.9 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD25016.1 - 7.2e-07 29.3 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 PVD25016.1 - 0.0031 16.8 0.3 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_trans_4_2 PF13477.6 PVD25016.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 PVD25016.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Mab-21 PF03281.14 PVD25017.1 - 5.4e-15 55.5 0.2 6.5e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 Mab-21 protein TFIIA PF03153.13 PVD25018.1 - 0.0086 16.1 7.3 0.0086 16.1 7.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PVD25018.1 - 0.16 11.6 19.6 0.21 11.2 19.6 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 PVD25018.1 - 4.6 6.3 14.4 6 6.0 14.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UDPGT PF00201.18 PVD25019.1 - 7.7e-72 242.7 0.0 1.3e-71 242.0 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD25019.1 - 5.6e-07 29.7 0.0 9.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 PVD25019.1 - 0.0024 17.2 0.2 0.09 12.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_trans_4_2 PF13477.6 PVD25019.1 - 0.0054 16.8 0.0 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like Mab-21 PF03281.14 PVD25020.1 - 0.00017 21.0 0.0 0.00039 19.8 0.1 1.5 2 0 0 2 2 2 1 Mab-21 protein LigT_PEase PF02834.16 PVD25020.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 LigT like Phosphoesterase Ninjurin PF04923.12 PVD25023.1 - 3.6e-30 103.9 2.1 4.1e-30 103.8 2.1 1.0 1 0 0 1 1 1 1 Ninjurin 7TM_GPCR_Srw PF10324.9 PVD25023.1 - 0.0078 15.5 0.2 0.0093 15.3 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2207 PF09972.9 PVD25023.1 - 0.15 10.8 0.5 0.15 10.8 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ion_trans PF00520.31 PVD25024.1 - 1.7e-37 129.0 10.7 2.2e-37 128.6 10.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD25024.1 - 4.8e-27 94.1 0.1 8.6e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD25024.1 - 2.6e-12 46.5 4.2 2.6e-12 46.5 4.2 2.2 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 PVD25024.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Ig_3 PF13927.6 PVD25026.1 - 1.3e-71 237.2 0.1 1e-17 64.5 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD25026.1 - 7.7e-70 231.0 0.4 7.2e-16 58.0 0.0 6.5 5 1 1 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD25026.1 - 5e-49 164.5 3.9 1.7e-12 47.5 0.0 6.9 6 1 1 7 7 7 5 Immunoglobulin domain ig PF00047.25 PVD25026.1 - 3.7e-44 148.8 0.2 1.1e-11 44.7 0.0 7.1 7 0 0 7 7 7 5 Immunoglobulin domain fn3 PF00041.21 PVD25026.1 - 3e-29 101.2 14.8 4.4e-09 36.6 1.8 6.3 6 0 0 6 6 6 4 Fibronectin type III domain V-set PF07686.17 PVD25026.1 - 1.3e-23 83.2 8.2 0.00012 22.2 0.3 9.1 6 5 1 7 7 7 3 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD25026.1 - 8.2e-12 45.4 0.0 0.038 14.4 0.0 4.7 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 PVD25026.1 - 3.6e-11 43.0 1.3 0.0045 17.0 0.0 6.3 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 PVD25026.1 - 4.6e-08 33.2 0.1 0.013 15.7 0.0 4.7 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD25026.1 - 1.5e-07 30.8 0.0 0.081 12.5 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin domain C1-set PF07654.15 PVD25026.1 - 0.0012 19.2 0.7 3.8 7.9 0.1 4.2 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 PVD25026.1 - 0.0026 17.8 0.2 5.5 7.1 0.0 3.9 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain fn3_2 PF16893.5 PVD25026.1 - 0.0034 17.5 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain DUF2207 PF09972.9 PVD25026.1 - 0.013 14.3 0.0 0.027 13.2 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BiPBP_C PF06832.12 PVD25026.1 - 0.036 14.1 0.0 6 7.0 0.0 3.1 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family E1-E2_ATPase PF00122.20 PVD25026.1 - 0.12 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 E1-E2 ATPase Pur_ac_phosph_N PF16656.5 PVD25026.1 - 2.6 8.7 10.5 0.39 11.3 0.5 3.9 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 PVD25027.1 - 5.3e-77 254.5 0.2 3e-18 66.2 0.1 6.5 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD25027.1 - 1.6e-74 246.0 0.0 2.2e-17 62.9 0.2 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD25027.1 - 5.7e-52 174.0 0.2 2.9e-12 46.7 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 PVD25027.1 - 1.4e-44 150.2 0.0 3.3e-12 46.4 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 PVD25027.1 - 1.5e-25 89.5 10.5 1e-05 25.6 0.3 10.5 7 5 1 8 8 8 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD25027.1 - 1.7e-12 47.3 0.3 0.00089 19.3 0.0 6.3 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD25027.1 - 2.4e-12 47.1 0.0 0.0055 17.1 0.0 4.8 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 PVD25027.1 - 6.5e-11 42.4 8.7 1.2e-05 25.6 2.9 4.5 3 1 0 3 3 3 2 Fibronectin type III domain Ig_4 PF16680.5 PVD25027.1 - 1.1e-08 35.2 0.6 0.008 16.4 0.0 4.9 5 1 0 5 5 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD25027.1 - 4.8e-08 32.4 0.0 0.033 13.7 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin domain C1-set PF07654.15 PVD25027.1 - 1.7e-05 25.1 0.1 1.5 9.2 0.1 4.6 5 0 0 5 5 4 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 PVD25027.1 - 0.00011 22.2 1.8 0.61 10.2 0.0 6.1 7 1 0 8 8 8 1 C17orf99 Ig domain Izumo-Ig PF16706.5 PVD25027.1 - 0.0047 17.0 0.1 11 6.1 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 PVD25027.1 - 0.075 13.1 0.0 15 5.7 0.0 3.0 3 0 0 3 3 2 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 PVD25027.1 - 0.14 12.3 0.0 5.9 7.1 0.1 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 MBD PF01429.19 PVD25028.1 - 8.8e-11 41.4 0.2 1.3e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Methyl-CpG binding domain AT_hook PF02178.19 PVD25028.1 - 0.087 12.7 6.1 0.31 11.1 6.1 1.9 1 0 0 1 1 1 0 AT hook motif Ank_2 PF12796.7 PVD25029.1 - 4e-32 110.7 4.2 3.9e-10 40.2 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD25029.1 - 2.5e-25 87.8 17.4 0.00028 21.2 0.1 9.5 8 1 1 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 PVD25029.1 - 1.8e-23 82.6 5.5 1e-05 25.9 0.0 7.8 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25029.1 - 3.9e-22 75.9 15.1 5.7e-05 23.2 0.0 9.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 PVD25029.1 - 1e-17 64.0 8.6 3.7e-05 23.9 0.0 7.1 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Viral_protease PF08715.10 PVD25031.1 - 2.1 7.6 3.9 0.51 9.6 0.2 1.8 3 0 0 3 3 3 0 Papain like viral protease Y_phosphatase PF00102.27 PVD25033.1 - 1.6e-23 83.5 5.3 3.9e-15 56.1 0.1 3.8 3 1 1 4 4 4 2 Protein-tyrosine phosphatase TMEM154 PF15102.6 PVD25033.1 - 3.3e-05 23.8 0.1 6.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PVD25033.1 - 0.00099 19.9 0.5 0.0039 18.0 0.1 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 PVD25033.1 - 0.001 19.2 0.5 0.0047 17.1 0.0 2.3 3 0 0 3 3 3 1 F5/8 type C domain CD34_antigen PF06365.12 PVD25033.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family PAT1 PF09770.9 PVD25034.1 - 4.3 5.5 57.3 5 5.3 57.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank_2 PF12796.7 PVD25035.1 - 9.7e-61 202.4 20.5 4.3e-11 43.2 0.8 8.8 8 0 0 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.30 PVD25035.1 - 9.8e-50 164.9 35.9 4.7e-06 26.8 0.2 16.1 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.6 PVD25035.1 - 1.5e-45 152.9 20.1 2.3e-06 28.0 0.1 13.2 8 3 6 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25035.1 - 4.5e-44 143.3 25.3 2.9e-05 24.1 0.0 15.5 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.6 PVD25035.1 - 1.6e-38 130.2 19.6 1.4e-07 31.6 0.0 11.1 6 2 6 12 12 12 8 Ankyrin repeats (many copies) CEP44 PF15007.6 PVD25035.1 - 0.02 15.1 0.4 32 4.7 0.0 4.1 3 2 2 5 5 5 0 Centrosomal spindle body, CEP44 TFIIA PF03153.13 PVD25035.1 - 0.03 14.3 26.5 0.046 13.7 26.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amidase_3 PF01520.18 PVD25035.1 - 0.04 14.0 0.0 8.1 6.5 0.0 2.9 3 0 0 3 3 3 0 N-acetylmuramoyl-L-alanine amidase GATase_7 PF13537.6 PVD25035.1 - 0.04 13.8 0.1 26 4.7 0.0 4.0 3 2 2 5 5 5 0 Glutamine amidotransferase domain PTS_EIIA_2 PF00359.22 PVD25035.1 - 0.053 13.4 4.1 3.1 7.7 0.2 2.7 3 0 0 3 3 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Dapper PF15268.6 PVD25035.1 - 0.054 12.3 15.3 0.079 11.8 15.3 1.1 1 0 0 1 1 1 0 Dapper Ndc1_Nup PF09531.10 PVD25035.1 - 7.3 5.2 15.1 12 4.5 15.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup I-set PF07679.16 PVD25036.1 - 9.2e-65 214.8 0.0 1.8e-16 60.0 0.0 6.8 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD25036.1 - 5.7e-64 212.7 0.0 3.8e-17 62.7 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 PVD25036.1 - 1e-42 144.3 0.2 4.1e-13 49.5 0.0 5.9 6 0 0 6 6 5 5 Immunoglobulin domain ig PF00047.25 PVD25036.1 - 1.4e-41 140.6 0.0 4.3e-11 42.8 0.0 6.9 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 PVD25036.1 - 1.4e-33 115.1 12.8 4.6e-09 36.5 0.0 6.5 6 1 0 6 6 6 5 Fibronectin type III domain V-set PF07686.17 PVD25036.1 - 2.1e-22 79.3 9.8 5.3e-05 23.3 0.3 9.6 8 5 0 8 8 6 3 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD25036.1 - 2.4e-09 37.5 0.1 0.053 13.9 0.0 4.5 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD25036.1 - 1.3e-08 34.2 0.2 0.04 13.5 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin domain Ig_4 PF16680.5 PVD25036.1 - 1.1e-07 32.0 1.7 0.0092 16.2 0.0 4.9 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD25036.1 - 1.3e-06 28.4 0.5 0.018 15.1 0.0 4.5 5 0 0 5 5 4 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD25036.1 - 3.3e-05 23.8 0.3 0.5 10.5 0.0 4.0 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 PVD25036.1 - 0.0006 20.0 0.0 0.55 10.5 0.0 4.1 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 C1-set PF07654.15 PVD25036.1 - 0.0065 16.8 0.7 3.4 8.1 0.1 4.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 PVD25036.1 - 0.022 15.3 6.9 0.056 14.0 0.1 4.5 5 0 0 5 5 4 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 PVD25036.1 - 0.026 14.7 0.0 1.2 9.3 0.0 3.1 3 0 0 3 3 3 0 Fibronectin type III domain Herpes_gE PF02480.16 PVD25036.1 - 0.03 13.1 0.1 13 4.4 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 PVD25036.1 - 0.13 12.3 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 C17orf99 Ig domain V-set_CD47 PF08204.11 PVD25036.1 - 0.17 11.9 0.4 62 3.6 0.0 3.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain I-set PF07679.16 PVD25037.1 - 1.1e-74 246.5 0.0 1.8e-16 60.0 0.0 6.8 7 0 0 7 7 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD25037.1 - 9e-74 244.1 0.0 3.8e-17 62.7 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 PVD25037.1 - 3.7e-50 168.2 0.1 4.1e-13 49.5 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 PVD25037.1 - 1.7e-48 162.7 0.0 4.2e-11 42.9 0.0 6.8 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 PVD25037.1 - 1.8e-34 117.9 12.1 4.3e-09 36.6 0.0 6.7 6 1 0 6 6 6 5 Fibronectin type III domain V-set PF07686.17 PVD25037.1 - 1.2e-23 83.3 8.5 0.00018 21.6 0.3 10.4 7 5 0 7 7 6 3 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD25037.1 - 6.7e-12 45.7 0.0 0.052 13.9 0.0 4.7 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD25037.1 - 8.7e-09 34.8 0.2 0.021 14.4 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin domain Ig_4 PF16680.5 PVD25037.1 - 3.7e-08 33.5 0.4 0.0092 16.2 0.0 4.9 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD25037.1 - 1e-07 31.9 0.3 0.018 15.1 0.0 5.1 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD25037.1 - 4e-05 23.6 0.2 0.52 10.4 0.0 3.9 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD25037.1 - 0.001 19.1 0.3 1.5 8.9 0.0 3.9 3 1 0 3 3 3 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 PVD25037.1 - 0.0065 16.6 0.0 5.9 7.1 0.1 4.1 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 C1-set PF07654.15 PVD25037.1 - 0.0085 16.5 1.3 3 8.3 0.1 4.0 4 0 0 4 4 2 1 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 PVD25037.1 - 0.035 14.7 7.8 0.087 13.4 0.1 4.8 5 0 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain DUF4834 PF16118.5 PVD25037.1 - 0.045 14.7 1.4 0.088 13.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) fn3_2 PF16893.5 PVD25037.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Fibronectin type III domain V-set_CD47 PF08204.11 PVD25037.1 - 0.17 11.8 0.4 79 3.2 0.0 3.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain DUF347 PF03988.12 PVD25037.1 - 0.22 11.8 1.3 0.52 10.5 1.3 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) BTB PF00651.31 PVD25039.1 - 2.6e-40 137.1 0.3 1.1e-19 70.7 0.2 3.2 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 PVD25039.1 - 5.9e-09 36.4 0.0 1.8e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25039.1 - 3.9e-08 33.7 0.1 1.1e-06 29.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD25039.1 - 9.6e-07 29.0 0.0 2.7e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25039.1 - 1e-05 25.5 0.1 0.01 16.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat BACK PF07707.15 PVD25039.1 - 0.00037 20.5 0.1 0.0011 19.0 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank PF00023.30 PVD25039.1 - 0.00072 19.9 0.0 0.0031 17.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 PVD25039.1 - 0.063 13.5 2.4 0.24 11.6 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3342) Adeno_E3_CR2 PF02439.15 PVD25040.1 - 0.0094 15.7 11.0 0.017 14.8 11.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PVD25040.1 - 0.043 14.7 0.0 0.043 14.7 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD25040.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.5 2 1 1 3 3 3 0 TMEM154 protein family Orthoreo_P10 PF07204.11 PVD25040.1 - 0.29 11.1 0.5 1.4 9.0 0.3 2.2 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 PVD25040.1 - 0.33 11.2 0.0 0.33 11.2 0.0 4.3 3 1 2 5 5 5 0 Wnt and FGF inhibitory regulator Syndecan PF01034.20 PVD25040.1 - 0.73 9.8 4.4 2 8.4 4.4 1.7 1 0 0 1 1 1 0 Syndecan domain RNase_T PF00929.24 PVD25041.1 - 1.4e-11 45.2 0.0 2.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 PVD25041.1 - 0.0021 17.8 0.0 0.015 15.0 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease UPF0542 PF15086.6 PVD25041.1 - 0.21 11.5 1.4 0.48 10.4 1.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF498 PF04430.14 PVD25042.1 - 3.2e-28 98.0 0.0 4.6e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) zf-C2H2 PF00096.26 PVD25043.1 - 7.1e-22 76.6 103.9 0.00033 20.9 2.3 12.1 12 0 0 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD25043.1 - 1.5e-10 41.0 89.2 3.8e-07 30.3 1.7 11.5 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD25043.1 - 9.9e-06 26.0 102.6 0.014 16.2 0.7 12.6 12 0 0 12 12 12 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD25043.1 - 0.00028 20.6 62.0 0.00077 19.2 4.6 8.6 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 PVD25043.1 - 0.51 10.7 39.4 0.24 11.7 2.4 6.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Ribosomal_L37ae PF01780.19 PVD25043.1 - 4.1 7.6 6.5 4.9 7.3 3.0 3.0 2 1 0 2 2 2 0 Ribosomal L37ae protein family ORC6 PF05460.13 PVD25044.1 - 0.0093 15.3 0.0 0.021 14.1 0.0 1.6 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) KinB_sensor PF16767.5 PVD25044.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Acyltransferase PF01553.21 PVD25045.1 - 4.4e-09 36.1 0.0 6.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Arg_tRNA_synt_N PF03485.16 PVD25045.1 - 0.037 14.6 0.0 0.055 14.1 0.0 1.2 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Copine PF07002.16 PVD25046.1 - 5.9e-70 235.1 0.0 3.8e-50 170.4 0.0 2.2 1 1 1 2 2 2 2 Copine C2 PF00168.30 PVD25046.1 - 1e-24 86.8 0.3 4.6e-14 52.6 0.0 2.7 2 1 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PVD25046.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus KDZ PF18758.1 PVD25046.1 - 0.12 11.9 0.1 0.37 10.4 0.1 1.8 1 1 0 2 2 2 0 Kyakuja-Dileera-Zisupton transposase Pox_Ag35 PF03286.14 PVD25047.1 - 2.2 8.1 6.7 4 7.2 6.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 PVD25047.1 - 2.7 7.3 7.3 4.5 6.5 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-T_N PF16171.5 PVD25047.1 - 7.6 5.3 6.0 12 4.7 6.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Ras PF00071.22 PVD25048.1 - 3.9e-57 192.4 0.0 4.6e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25048.1 - 1.4e-32 112.4 0.0 2.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD25048.1 - 1.1e-12 47.7 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD25048.1 - 3.7e-07 30.2 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD25048.1 - 2.8e-05 23.6 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PVD25048.1 - 7.1e-05 22.8 0.1 0.0032 17.4 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PVD25048.1 - 0.00012 21.7 0.1 0.013 15.0 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PVD25048.1 - 0.00033 20.4 0.1 0.12 12.2 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 PVD25048.1 - 0.0012 18.7 0.2 0.042 13.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 PVD25048.1 - 0.0015 18.2 0.0 0.0068 16.0 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 PVD25048.1 - 0.0016 17.8 0.5 0.02 14.2 0.1 2.1 2 1 0 2 2 2 1 Septin AAA_22 PF13401.6 PVD25048.1 - 0.0049 17.2 0.1 0.018 15.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 PVD25048.1 - 0.0097 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 PVD25048.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PVD25048.1 - 0.02 15.3 0.1 0.03 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 PVD25048.1 - 0.02 14.6 0.1 0.032 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PVD25048.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 PVD25048.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 PVD25048.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 PVD25048.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 PVD25048.1 - 0.083 12.0 0.6 0.18 10.9 0.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 PVD25048.1 - 0.09 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 PVD25048.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain OTU PF02338.19 PVD25049.1 - 2.8e-15 56.9 1.2 5.5e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PVD25049.1 - 0.0025 17.3 2.1 0.13 11.7 0.5 2.4 1 1 0 2 2 2 2 Peptidase C65 Otubain p450 PF00067.22 PVD25050.1 - 1.4e-17 63.6 5.9 1.1e-15 57.4 5.9 2.3 1 1 0 1 1 1 1 Cytochrome P450 HMG_box PF00505.19 PVD25051.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD25051.1 - 0.0038 17.8 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 PVD25052.1 - 3.3e-24 85.7 0.0 3.8e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25052.1 - 1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD25052.1 - 2.2e-07 30.4 0.0 2.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD25052.1 - 0.0079 16.1 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PVD25052.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 PVD25052.1 - 0.014 14.4 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PVD25052.1 - 0.017 14.5 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 PVD25052.1 - 0.032 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PVD25052.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 PVD25053.1 - 9.2e-05 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PVD25062.1 - 1.1e-21 77.2 3.7 1.3e-06 28.9 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD25062.1 - 1.4e-18 65.0 1.3 0.0014 18.9 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 PVD25062.1 - 2.1e-17 63.3 1.8 0.00072 20.1 0.0 6.9 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD25062.1 - 1.2e-15 57.1 1.6 0.00029 21.2 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PVD25062.1 - 1.3e-14 54.1 9.1 2.8e-05 24.3 0.1 7.0 6 2 1 7 7 7 4 Ankyrin repeats (many copies) zf-MYND PF01753.18 PVD25062.1 - 0.007 16.4 9.5 0.007 16.4 9.5 2.6 2 1 0 2 2 2 1 MYND finger G-patch PF01585.23 PVD25063.1 - 1.1e-12 47.6 2.3 2.1e-12 46.7 0.6 2.2 2 0 0 2 2 2 1 G-patch domain DUF1366 PF07104.11 PVD25063.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) CDC45 PF02724.14 PVD25063.1 - 0.26 9.5 3.4 0.34 9.2 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DIM1 PF02966.16 PVD25064.1 - 1.3e-52 177.1 0.1 1.5e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PVD25064.1 - 8.5e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UvrD_C PF13361.6 PVD25065.1 - 1.5e-13 50.9 0.6 1.4e-12 47.7 0.2 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PVD25065.1 - 2.8e-12 47.2 0.0 1e-11 45.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 PVD25065.1 - 1.1e-11 44.8 5.8 3.6e-09 36.6 0.1 3.6 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 PVD25065.1 - 4.8e-10 39.1 0.1 1.6e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PVD25065.1 - 1.4e-06 28.2 8.1 0.052 13.3 0.0 4.7 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase F-box PF00646.33 PVD25065.1 - 0.00013 21.7 0.3 0.00049 19.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PVD25065.1 - 0.0004 20.2 0.6 0.0011 18.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like AAA_22 PF13401.6 PVD25065.1 - 0.0054 17.0 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD25065.1 - 0.0077 16.0 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain CUB PF00431.20 PVD25066.1 - 4e-71 236.4 0.3 3.8e-28 98.0 0.0 3.4 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.26 PVD25066.1 - 2.4e-53 181.2 0.0 4.2e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin I-set PF07679.16 PVD25066.1 - 4.4e-18 65.1 0.0 8.4e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD25066.1 - 5.2e-17 62.2 0.0 5.4e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD25066.1 - 1.6e-15 57.0 0.0 6.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD25066.1 - 2.8e-13 50.0 0.0 1.7e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain EGF PF00008.27 PVD25066.1 - 1.2e-07 31.9 12.6 0.0039 17.5 0.3 3.4 2 1 0 2 2 2 2 EGF-like domain V-set PF07686.17 PVD25066.1 - 0.0015 18.7 0.3 40 4.4 0.0 4.4 2 2 0 4 4 4 0 Immunoglobulin V-set domain EGF_2 PF07974.13 PVD25066.1 - 0.0016 18.8 20.2 0.2 12.1 6.0 3.3 2 0 0 2 2 2 2 EGF-like domain Ig_6 PF18452.1 PVD25066.1 - 0.0054 16.3 0.1 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 PVD25066.1 - 0.05 14.0 0.0 0.47 10.9 0.0 2.3 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF316 PF03761.15 PVD25066.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 PVD25066.1 - 0.087 13.2 0.0 0.63 10.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1986) FXa_inhibition PF14670.6 PVD25066.1 - 0.12 12.7 15.5 0.49 10.7 5.0 3.1 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 PVD25066.1 - 2.1 8.6 16.7 4.6 7.5 3.7 2.8 1 1 1 2 2 2 0 Laminin EGF domain hEGF PF12661.7 PVD25066.1 - 2.2 9.0 13.1 16 6.3 5.3 4.1 2 1 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.7 PVD25066.1 - 5 7.1 11.3 4.5 7.3 0.5 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like DCB PF16213.5 PVD25067.1 - 3e-65 219.2 7.6 3e-65 219.2 7.6 2.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 PVD25067.1 - 1e-50 171.8 3.5 1.6e-50 171.1 0.2 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PVD25067.1 - 0.12 12.2 4.0 4.4 7.2 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Cache_3-Cache_2 PF17201.4 PVD25071.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain 7TM_GPCR_Srw PF10324.9 PVD25072.1 - 1.2e-40 139.8 25.7 1.5e-40 139.5 25.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD25072.1 - 3e-16 59.6 21.5 5.6e-16 58.7 21.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 PVD25072.1 - 0.062 13.6 14.5 0.51 10.7 0.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) PRIMA1 PF16101.5 PVD25073.1 - 0.0086 16.1 5.5 0.009 16.0 5.5 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD25073.1 - 0.067 12.7 3.6 0.07 12.6 3.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Androgen_recep PF02166.16 PVD25073.1 - 0.18 10.6 3.1 0.18 10.6 3.1 1.1 1 0 0 1 1 1 0 Androgen receptor Mito_fiss_reg PF05308.11 PVD25073.1 - 1.1 9.3 2.9 1 9.4 2.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Mon2_C PF16206.5 PVD25080.1 - 1.3e-243 810.6 0.4 8.1e-229 761.8 0.1 2.7 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 PVD25080.1 - 1.9e-13 50.0 0.0 6.7e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) HEAT PF02985.22 PVD25080.1 - 0.11 12.8 2.3 41 4.8 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat bZIP_2 PF07716.15 PVD25081.1 - 1.7e-08 34.4 14.5 1.7e-08 34.4 14.5 1.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD25081.1 - 0.63 10.2 14.9 0.98 9.6 14.9 1.4 1 1 0 1 1 1 0 bZIP transcription factor TatD_DNase PF01026.21 PVD25082.1 - 3e-57 193.9 1.9 1.4e-56 191.7 0.1 2.4 3 0 0 3 3 3 1 TatD related DNase ANF_receptor PF01094.28 PVD25083.1 - 1.1e-69 235.3 0.0 7.8e-35 120.6 0.0 2.4 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD25083.1 - 7.9e-25 88.2 0.1 2.1e-13 50.7 0.1 3.0 2 1 0 2 2 2 2 Periplasmic binding protein Fasciclin PF02469.22 PVD25084.1 - 7e-60 200.9 0.1 1e-30 106.6 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF1866 PF08952.11 PVD25084.1 - 0.12 12.2 0.0 1.3 8.9 0.0 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF1866) DEP PF00610.21 PVD25085.1 - 5.8e-13 48.7 0.0 1.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 PVD25085.1 - 7.5e-09 36.0 0.0 3.1e-06 27.6 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 PVD25085.1 - 0.0068 16.8 0.0 2 8.8 0.2 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain Sharpin_PH PF16764.5 PVD25085.1 - 0.026 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sharpin PH domain PH_6 PF15406.6 PVD25085.1 - 0.079 13.2 0.0 14 6.0 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain LSM PF01423.22 PVD25089.1 - 4.4e-15 55.1 0.4 5e-15 54.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain DNA_pol3_tau_5 PF12170.8 PVD25089.1 - 0.011 15.8 0.3 0.013 15.6 0.3 1.2 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha SAS-6_N PF16531.5 PVD25089.1 - 0.065 13.8 0.2 14 6.3 0.2 2.0 1 1 1 2 2 2 0 Centriolar protein SAS N-terminal DUF150_C PF17384.2 PVD25089.1 - 0.11 12.6 0.4 0.19 11.9 0.4 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Muskelin_N PF06588.11 PVD25090.1 - 2.6e-88 295.2 0.7 2.6e-88 295.2 0.7 1.7 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.6 PVD25090.1 - 1.2e-23 82.9 3.5 4.4e-08 33.2 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD25090.1 - 1.3e-16 60.4 4.6 0.00016 21.6 0.2 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD25090.1 - 6.4e-16 58.0 3.6 0.00025 21.2 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PVD25090.1 - 3.3e-11 42.6 10.3 0.00074 19.1 0.6 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PVD25090.1 - 1.8e-10 40.5 6.3 0.0013 18.7 0.1 6.2 7 0 0 7 7 7 2 Kelch motif F5_F8_type_C PF00754.25 PVD25090.1 - 1.4e-08 34.9 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.15 PVD25090.1 - 1.8e-07 30.8 8.8 0.048 13.7 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Sad1_UNC PF07738.13 PVD25090.1 - 0.0014 18.7 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EF-hand_6 PF13405.6 PVD25091.1 - 1.4e-15 55.8 2.1 0.00018 21.2 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD25091.1 - 3.2e-15 56.3 10.3 7.7e-08 32.7 0.8 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD25091.1 - 4.9e-14 50.7 6.5 0.00011 21.5 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD25091.1 - 2.5e-08 33.6 0.3 6.7e-05 22.6 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD25091.1 - 8.7e-08 31.3 0.4 0.012 15.1 0.0 3.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD25091.1 - 0.0063 16.8 2.2 0.21 11.9 1.5 2.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD25091.1 - 0.023 14.6 2.9 0.46 10.5 0.2 3.1 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand AICARFT_IMPCHas PF01808.18 PVD25091.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme ATP-synt_S1 PF05827.12 PVD25092.1 - 9.9e-28 96.8 0.2 1.8e-27 95.9 0.2 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Ribosom_S12_S23 PF00164.25 PVD25093.1 - 5.9e-53 177.3 0.7 7.4e-53 177.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SEFIR PF08357.11 PVD25094.1 - 3.9e-05 24.0 0.2 0.00043 20.6 0.1 2.1 2 0 0 2 2 2 1 SEFIR domain Y_Y_Y PF07495.13 PVD25094.1 - 0.17 11.8 0.1 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain BTB PF00651.31 PVD25097.1 - 8.6e-26 90.3 0.0 1.6e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD25097.1 - 6.3e-25 87.3 1.2 3.1e-24 85.0 0.3 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD25097.1 - 2.4e-24 84.7 4.8 7.1e-10 38.3 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PVD25097.1 - 7.9e-15 54.5 2.9 0.0088 16.3 0.0 6.0 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.6 PVD25097.1 - 6.1e-11 42.1 2.8 0.14 12.2 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD25097.1 - 2.3e-10 40.5 0.0 0.056 13.8 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD25097.1 - 4.2e-10 39.2 1.1 0.0028 17.6 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 PVD25097.1 - 2.4e-08 33.8 0.2 0.0029 17.6 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Ig_2 PF13895.6 PVD25098.1 - 1.5e-20 73.3 2.0 1.6e-12 47.6 0.1 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 PVD25098.1 - 2.5e-20 72.8 8.3 4.4e-15 56.0 0.1 5.0 4 1 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD25098.1 - 2.6e-14 53.1 0.1 3.4e-12 46.3 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 PVD25098.1 - 7.1e-12 45.3 11.6 4.5e-11 42.8 0.1 4.4 3 2 1 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD25098.1 - 4.2e-09 36.4 17.7 7.9e-05 22.6 0.0 4.7 3 2 1 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD25098.1 - 2.9e-07 30.8 0.4 9.3e-05 22.8 0.0 3.4 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 PVD25098.1 - 2.6e-05 24.4 5.5 1.4 9.1 0.0 4.8 3 2 1 4 4 4 2 Immunoglobulin V-set domain TMEM154 PF15102.6 PVD25098.1 - 0.0004 20.3 3.1 0.0011 18.9 3.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.17 PVD25098.1 - 0.0011 18.9 19.5 0.0011 18.9 19.5 1.9 2 0 0 2 2 1 1 Mucin-like glycoprotein Ig_4 PF16680.5 PVD25098.1 - 0.0024 18.1 0.6 0.084 13.1 0.0 3.1 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain SKG6 PF08693.10 PVD25098.1 - 0.0093 15.4 2.2 0.019 14.3 2.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 PVD25098.1 - 0.015 14.2 0.2 0.023 13.6 0.2 1.2 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 PVD25098.1 - 0.035 13.7 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Phage_Coat_B PF05356.11 PVD25098.1 - 0.05 13.5 0.5 0.099 12.6 0.5 1.5 1 0 0 1 1 1 0 Phage Coat protein B RIFIN PF02009.16 PVD25098.1 - 0.096 12.6 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Rifin DUF3439 PF11921.8 PVD25098.1 - 0.25 11.3 14.4 0.79 9.7 14.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 PVD25098.1 - 0.3 9.0 4.1 0.43 8.5 4.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5305 PF17231.2 PVD25098.1 - 0.32 10.4 3.8 0.63 9.4 3.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MGC-24 PF05283.11 PVD25098.1 - 0.41 11.1 14.6 0.16 12.4 11.1 2.2 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tir_receptor_C PF07489.11 PVD25098.1 - 9.3 6.2 15.6 68 3.3 12.8 2.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus S1FA PF04689.13 PVD25099.1 - 0.066 13.4 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DSL PF01414.19 PVD25099.1 - 0.96 9.8 15.0 1.3 9.4 5.5 2.4 2 0 0 2 2 2 0 Delta serrate ligand Rhodanese PF00581.20 PVD25100.1 - 1.4e-10 41.6 0.0 3.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Arrestin_N PF00339.29 PVD25102.1 - 9.2e-16 58.2 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD25102.1 - 5.1e-12 46.4 0.0 4e-11 43.5 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD25102.1 - 0.037 13.2 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 Rgp1 DUF19 PF01579.18 PVD25103.1 - 0.087 12.6 10.1 0.92 9.3 10.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF4455 PF14643.6 PVD25103.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) EphA2_TM PF14575.6 PVD25105.1 - 1.5 9.7 3.5 10 7.1 0.8 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UvrC_HhH_N PF08459.11 PVD25107.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal TMEM100 PF16311.5 PVD25111.1 - 0.0016 18.0 3.5 0.0021 17.7 0.8 2.0 1 1 1 2 2 2 1 Transmembrane protein 100 DUF3561 PF12084.8 PVD25111.1 - 0.026 14.5 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) TMEM154 PF15102.6 PVD25111.1 - 0.06 13.2 1.8 0.065 13.1 0.3 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF3377 PF11857.8 PVD25111.1 - 0.11 12.5 2.7 0.2 11.6 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2207 PF09972.9 PVD25111.1 - 0.11 11.3 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 PVD25111.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 PVD25111.1 - 0.2 12.6 1.6 0.72 10.8 0.6 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_31 PF01055.26 PVD25114.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Saf_2TM PF18303.1 PVD25114.1 - 0.18 11.4 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Glyco_hydro_31 PF01055.26 PVD25115.1 - 1.3e-12 47.6 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 B12D PF06522.11 PVD25117.1 - 0.077 12.8 0.7 0.42 10.4 1.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ac76 PF05814.11 PVD25118.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) Spectrin PF00435.21 PVD25120.1 - 0.07 13.6 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Spectrin repeat Spectrin PF00435.21 PVD25121.1 - 0.07 13.6 0.1 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 Spectrin repeat FlxA PF14282.6 PVD25121.1 - 0.082 12.9 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 FlxA-like protein MAD PF05557.13 PVD25121.1 - 0.12 10.7 2.4 0.16 10.3 2.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein V_ATPase_I PF01496.19 PVD25121.1 - 0.31 8.9 0.0 0.39 8.6 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 PVD25121.1 - 0.44 11.0 2.0 5.5 7.5 2.0 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 PVD25121.1 - 0.76 9.2 3.0 0.49 9.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TRIQK PF15168.6 PVD25122.1 - 0.094 12.6 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family FYVE_2 PF02318.16 PVD25122.1 - 0.22 11.7 1.5 0.44 10.8 1.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Molybdop_Fe4S4 PF04879.16 PVD25124.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain PSK_trans_fac PF07704.11 PVD25127.1 - 0.046 14.5 1.1 0.21 12.4 1.1 2.1 1 0 0 1 1 1 0 Rv0623-like transcription factor TFIIA PF03153.13 PVD25127.1 - 0.52 10.3 23.0 0.34 10.9 21.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDZ PF00595.24 PVD25128.1 - 4.8e-12 46.1 0.2 1.1e-11 44.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD25128.1 - 3e-10 39.8 0.1 5.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain ORC6 PF05460.13 PVD25128.1 - 1.9 7.7 9.6 3.7 6.7 9.6 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nucleo_P87 PF07267.11 PVD25128.1 - 9.4 4.9 8.7 16 4.2 8.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 C2 PF00168.30 PVD25129.1 - 1.6e-26 92.6 0.0 2.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.9 PVD25129.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins CD225 PF04505.12 PVD25130.1 - 1.3e-15 57.3 0.3 2.8e-14 53.0 0.2 2.1 2 0 0 2 2 2 1 Interferon-induced transmembrane protein VIT1 PF01988.19 PVD25130.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 VIT family NAPRTase PF04095.16 PVD25131.1 - 2e-70 237.1 0.0 2.6e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 PVD25131.1 - 2.4e-41 140.1 0.1 5e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) LIM PF00412.22 PVD25132.1 - 1.2e-09 38.2 5.8 2.1e-09 37.4 5.8 1.3 1 0 0 1 1 1 1 LIM domain GyrI-like PF06445.15 PVD25134.1 - 0.0017 18.7 0.1 0.0032 17.8 0.1 1.5 1 0 0 1 1 1 1 GyrI-like small molecule binding domain FixS PF03597.15 PVD25134.1 - 0.016 14.9 4.2 0.022 14.5 2.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Cass2 PF14526.6 PVD25134.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Integron-associated effector binding protein FYVE PF01363.21 PVD25135.1 - 2.6e-18 65.9 9.1 4.9e-18 65.0 4.9 2.5 2 0 0 2 2 2 1 FYVE zinc finger Rbsn PF11464.8 PVD25135.1 - 8e-16 57.5 4.3 2.5e-15 55.9 4.3 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 PVD25135.1 - 0.0028 17.9 0.4 0.0028 17.9 0.4 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_9 PF13901.6 PVD25135.1 - 0.0067 16.4 0.5 0.0067 16.4 0.5 2.1 3 0 0 3 3 3 1 Putative zinc-RING and/or ribbon DUF4228 PF14009.6 PVD25135.1 - 0.11 12.9 2.4 0.22 11.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) zf_C2H2_ZHX PF18387.1 PVD25135.1 - 0.7 9.6 2.3 2.7 7.7 0.1 2.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain L51_S25_CI-B8 PF05047.16 PVD25136.1 - 8.7e-12 44.8 0.1 1.6e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF5618 PF18498.1 PVD25136.1 - 0.11 12.6 0.1 21 5.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Arm_2 PF04826.13 PVD25137.1 - 5.7e-17 62.0 3.4 1.3e-16 60.9 3.4 1.6 1 1 0 1 1 1 1 Armadillo-like DCP1 PF06058.13 PVD25138.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Ion_trans PF00520.31 PVD25140.1 - 2.2e-247 816.3 86.8 1.5e-67 227.4 23.1 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 PVD25140.1 - 1.9e-31 108.1 0.0 5.7e-31 106.6 0.0 1.9 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 PVD25140.1 - 7.4e-29 99.3 0.1 2.4e-28 97.6 0.1 2.0 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 PVD25140.1 - 5e-10 38.6 93.2 4.9e-06 25.5 9.1 9.4 6 4 3 9 9 9 5 Polycystin cation channel CAC1F_C PF16885.5 PVD25140.1 - 2.6e-09 37.2 36.9 8e-08 32.3 0.0 4.2 4 1 0 4 4 4 2 Voltage-gated calcium channel subunit alpha, C-term GET2 PF08690.10 PVD25140.1 - 0.0047 16.6 0.6 0.0047 16.6 0.6 3.0 3 0 0 3 3 3 1 GET complex subunit GET2 Zip PF02535.22 PVD25140.1 - 0.4 9.8 4.3 44 3.2 3.5 3.7 2 1 0 2 2 2 0 ZIP Zinc transporter SieB PF14163.6 PVD25140.1 - 4.9 6.6 12.7 1.1 8.8 0.0 3.7 4 0 0 4 4 4 0 Super-infection exclusion protein B Y_phosphatase PF00102.27 PVD25141.1 - 2.6e-111 370.8 0.0 3.3e-76 256.0 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 PVD25141.1 - 1.6e-05 24.8 0.1 0.00088 19.1 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD25141.1 - 0.0057 16.6 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family LIDHydrolase PF10230.9 PVD25141.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PTPlike_phytase PF14566.6 PVD25141.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Ank_4 PF13637.6 PVD25142.1 - 5.2e-16 58.8 3.9 0.00014 22.3 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD25142.1 - 2.6e-15 56.7 0.5 5e-09 36.6 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD25142.1 - 9.1e-14 50.2 1.6 0.00083 19.6 0.2 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PVD25142.1 - 5.5e-12 45.7 1.0 0.00072 19.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD25142.1 - 2.9e-08 33.8 3.6 0.021 15.3 0.3 4.4 4 0 0 4 4 4 3 Ankyrin repeat SOCS_box PF07525.16 PVD25142.1 - 1.5e-05 25.3 1.1 3.6e-05 24.0 1.1 1.7 1 0 0 1 1 1 1 SOCS box Phage_T7_Capsid PF05396.11 PVD25142.1 - 0.24 11.8 0.1 1.4 9.3 0.0 2.2 2 1 1 3 3 3 0 Phage T7 capsid assembly protein CC2-LZ PF16516.5 PVD25143.1 - 1.5e-18 67.0 8.7 1.5e-18 67.0 8.7 6.6 3 2 1 6 6 6 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf_C2H2_10 PF18414.1 PVD25143.1 - 1.2e-06 27.9 2.0 2.3e-06 27.0 2.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger NEMO PF11577.8 PVD25143.1 - 2.8e-05 24.0 14.8 2.8e-05 24.0 14.8 5.8 5 1 1 6 6 6 1 NF-kappa-B essential modulator NEMO NAS PF03059.16 PVD25143.1 - 0.083 12.2 7.1 0.31 10.3 0.1 2.7 2 0 0 2 2 2 0 Nicotianamine synthase protein CEP63 PF17045.5 PVD25143.1 - 0.27 11.1 89.3 1.2 9.0 18.7 3.3 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Spc7 PF08317.11 PVD25143.1 - 0.41 9.5 93.9 1.7 7.5 23.1 5.4 2 2 3 5 5 5 0 Spc7 kinetochore protein APG6_N PF17675.1 PVD25143.1 - 2.2 8.8 106.0 0.18 12.3 15.1 5.5 2 2 2 5 5 5 0 Apg6 coiled-coil region F-actin_cap_A PF01267.17 PVD25146.1 - 6.9e-102 340.4 0.2 7.9e-102 340.2 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 PVD25146.1 - 0.038 13.6 0.8 0.057 13.0 0.8 1.3 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Ldl_recept_a PF00057.18 PVD25147.1 - 4.1e-20 71.7 24.4 1.6e-10 41.0 9.1 2.4 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD25148.1 - 4.1e-22 78.1 29.1 8.2e-12 45.1 12.6 2.1 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD25149.1 - 5.3e-25 87.3 34.3 1e-12 48.0 12.9 2.1 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD25150.1 - 2.7e-32 110.7 50.2 1.4e-12 47.6 15.1 3.1 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD25151.1 - 6.2e-20 71.1 39.0 2.7e-11 43.5 13.3 2.4 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Sugar_tr PF00083.24 PVD25153.1 - 7.6e-97 325.0 15.0 4.9e-66 223.4 0.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD25153.1 - 3.6e-23 82.1 10.1 1.5e-15 57.0 5.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD25153.1 - 0.001 17.7 19.3 0.016 13.8 6.4 3.3 2 2 0 2 2 2 2 MFS/sugar transport protein DUF2318 PF10080.9 PVD25153.1 - 0.069 13.3 2.7 0.12 12.5 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PUCC PF03209.15 PVD25153.1 - 0.49 9.3 8.2 0.52 9.3 0.0 3.0 3 1 0 3 3 3 0 PUCC protein 7tm_1 PF00001.21 PVD25154.1 - 7.9e-25 87.7 0.3 1.8e-24 86.5 0.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD25154.1 - 0.0004 20.1 4.6 0.00064 19.4 4.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD25154.1 - 0.02 14.3 4.5 0.02 14.3 2.5 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx SEFIR PF08357.11 PVD25155.1 - 3.6e-26 92.2 0.0 6.4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 SEFIR domain LPG_synthase_TM PF03706.13 PVD25155.1 - 0.065 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Glyco_transf_52 PF07922.11 PVD25155.1 - 0.23 10.7 0.1 1.3 8.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 52 Usp PF00582.26 PVD25156.1 - 3e-21 76.4 0.2 3.3e-21 76.3 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF1151 PF06625.11 PVD25157.1 - 5.6e-25 87.5 14.5 5.6e-25 87.5 14.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1151) SH3_2 PF07653.17 PVD25157.1 - 3.8e-08 32.9 0.0 6.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD25157.1 - 7e-07 28.8 2.0 8.2e-07 28.5 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 PVD25157.1 - 0.004 17.4 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain POPLD PF08170.12 PVD25157.1 - 0.75 10.2 2.8 0.65 10.4 1.1 1.7 2 0 0 2 2 2 0 POPLD (NUC188) domain Seryl_tRNA_N PF02403.22 PVD25158.1 - 0.0026 17.9 4.4 0.0026 17.9 4.4 2.4 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF3288 PF11691.8 PVD25158.1 - 0.31 11.1 3.8 1.4 9.0 0.8 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3288) She9_MDM33 PF05546.11 PVD25158.1 - 0.41 10.4 11.7 0.13 12.1 8.2 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family Fez1 PF06818.15 PVD25158.1 - 1.1 9.6 20.1 1.7 9.1 20.1 1.3 1 1 0 1 1 1 0 Fez1 HMMR_C PF15908.5 PVD25158.1 - 1.9 8.7 11.6 15 5.8 7.9 3.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Pantoate_ligase PF02569.15 PVD25158.1 - 1.9 7.6 8.2 0.29 10.3 3.9 1.7 1 1 1 2 2 2 0 Pantoate-beta-alanine ligase Peptidase_S46 PF10459.9 PVD25158.1 - 5 5.6 10.6 6.2 5.3 10.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Occludin_ELL PF07303.13 PVD25158.1 - 5.6 7.8 8.6 0.84 10.4 1.3 2.4 1 1 1 2 2 2 0 Occludin homology domain YusW PF14039.6 PVD25158.1 - 6.1 7.4 7.7 1.6 9.3 1.1 2.7 2 1 1 3 3 3 0 YusW-like protein MAGE PF01454.19 PVD25159.1 - 5e-25 88.5 0.0 1.5e-23 83.6 0.0 2.1 1 1 0 1 1 1 1 MAGE family BAR_3 PF16746.5 PVD25162.1 - 2.8e-59 200.7 15.5 4.3e-59 200.1 15.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PID PF00640.23 PVD25162.1 - 2.2e-17 63.4 0.6 6.7e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.29 PVD25162.1 - 3.1e-11 43.7 0.2 2.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 PH domain PTB PF08416.13 PVD25162.1 - 5.8e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_17 PF18012.1 PVD25162.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 PH domain PH_13 PF16652.5 PVD25162.1 - 0.027 14.3 0.1 0.085 12.7 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 PVD25162.1 - 0.041 14.3 0.1 0.23 11.8 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PID_2 PF14719.6 PVD25162.1 - 0.044 13.7 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) IBR PF01485.21 PVD25164.1 - 4.3e-11 42.9 34.3 4e-07 30.2 6.2 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 PVD25164.1 - 0.0045 17.1 25.1 1.5 9.0 4.1 3.8 3 1 0 3 3 3 3 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD25164.1 - 0.028 14.3 0.3 0.028 14.3 0.3 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PVD25164.1 - 0.86 9.5 36.4 1.7 8.5 1.6 4.6 4 1 1 5 5 5 0 RING/Ubox like zinc-binding domain PTS_IIA PF02255.16 PVD25165.1 - 0.1 12.6 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Transketolase_N PF00456.21 PVD25166.1 - 4.4e-47 160.6 0.0 7.2e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PVD25166.1 - 2.6e-35 121.7 0.1 5e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 PVD25166.1 - 4.5e-12 45.5 0.0 7.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PVD25166.1 - 1.8e-06 27.4 0.0 0.00061 19.1 0.0 2.8 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 PVD25166.1 - 6.2e-05 22.0 0.0 9.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.21 PVD25166.1 - 0.00011 22.0 0.0 0.0049 16.7 0.1 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 PVD25167.1 - 5.8e-31 107.0 0.1 6.6e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Saf-Nte_pilin PF09460.10 PVD25167.1 - 0.063 13.3 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Ribosomal_L18A PF01775.17 PVD25168.1 - 1.4e-54 183.4 0.1 1.7e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A US30 PF17624.2 PVD25168.1 - 0.05 12.7 0.2 0.064 12.3 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function Xpo1 PF08389.12 PVD25169.1 - 2e-35 122.1 0.9 2.2e-34 118.7 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_EZ PF13513.6 PVD25169.1 - 0.021 15.3 0.8 41 4.8 0.0 4.6 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 PVD25169.1 - 0.067 13.5 0.1 26 5.4 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 PVD25169.1 - 0.13 12.4 0.1 2.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2046 PF09755.9 PVD25170.1 - 0.061 12.6 0.3 0.097 11.9 0.3 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Dynamitin PF04912.14 PVD25171.1 - 0.0012 18.3 1.3 0.0016 17.9 1.3 1.1 1 0 0 1 1 1 1 Dynamitin DUF2046 PF09755.9 PVD25171.1 - 0.018 14.3 1.4 0.024 13.9 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cytochrom_CIII PF02085.16 PVD25171.1 - 0.098 13.0 0.6 0.18 12.2 0.6 1.4 1 0 0 1 1 1 0 Class III cytochrome C family DUF2046 PF09755.9 PVD25172.1 - 0.00018 20.8 9.3 0.05 12.8 1.1 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Cytochrom_CIII PF02085.16 PVD25172.1 - 0.0039 17.5 2.6 1 9.7 0.6 2.5 2 0 0 2 2 2 2 Class III cytochrome C family MCR_C PF04609.12 PVD25172.1 - 0.013 14.6 3.4 0.16 11.0 0.3 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Herpes_env PF01673.18 PVD25172.1 - 0.034 13.1 0.5 0.064 12.2 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein DUF411 PF04214.13 PVD25172.1 - 0.034 14.1 0.8 6.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF TSC22 PF01166.18 PVD25172.1 - 0.071 13.4 8.8 39 4.7 0.0 4.3 4 0 0 4 4 4 0 TSC-22/dip/bun family Lectin_N PF03954.14 PVD25172.1 - 0.096 12.4 11.8 0.16 11.7 2.3 3.2 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF2618 PF10940.8 PVD25172.1 - 0.32 10.8 4.2 7 6.5 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) HOOK PF05622.12 PVD25172.1 - 1.4 7.0 10.8 0.93 7.6 1.5 2.6 2 1 0 2 2 2 0 HOOK protein Cytochrom_c3_2 PF14537.6 PVD25172.1 - 2.5 8.6 7.3 11 6.6 0.1 2.9 3 0 0 3 3 2 0 Cytochrome c3 FlaF PF07309.11 PVD25172.1 - 2.8 8.0 5.9 18 5.4 0.3 2.5 2 0 0 2 2 2 0 Flagellar protein FlaF Myc-LZ PF02344.15 PVD25172.1 - 3.2 7.9 4.9 29 4.9 0.7 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Cytochrom_CIII PF02085.16 PVD25173.1 - 0.092 13.1 0.9 0.21 12.0 0.9 1.5 1 0 0 1 1 1 0 Class III cytochrome C family CCDC92 PF14916.6 PVD25174.1 - 0.5 10.2 2.4 1.1 9.0 0.1 2.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function HlyIII PF03006.20 PVD25175.1 - 2.2e-73 246.7 22.1 2.6e-73 246.4 22.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related CopD PF05425.13 PVD25175.1 - 0.0036 17.7 6.0 0.0049 17.2 0.9 2.8 3 0 0 3 3 3 1 Copper resistance protein D DUF4131 PF13567.6 PVD25175.1 - 2.5 7.8 16.2 0.2 11.3 0.6 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Polysacc_synt_C PF14667.6 PVD25175.1 - 3.6 7.6 17.7 0.1 12.6 1.0 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain MRP-S33 PF08293.11 PVD25177.1 - 6.8e-23 80.7 0.9 8e-23 80.5 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Guanylate_kin PF00625.21 PVD25178.1 - 5.4e-35 120.7 0.0 1.1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.7 PVD25178.1 - 3.8e-15 55.8 30.6 2.8e-06 27.5 4.3 5.7 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD25178.1 - 9.3e-13 48.0 2.7 9.3e-13 48.0 2.7 2.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 PVD25178.1 - 6.7e-12 45.0 30.1 0.00025 20.7 10.0 5.2 3 1 0 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 PVD25178.1 - 0.089 12.9 29.2 3 8.1 0.1 7.1 8 0 0 8 8 8 0 Leucine Rich repeat GTP_EFTU PF00009.27 PVD25179.1 - 2.5e-51 174.0 0.0 4.8e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FAM194 PF14977.6 PVD25179.1 - 2.7e-23 82.3 0.0 5.9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 FAM194 protein GTP_EFTU_D3 PF03143.17 PVD25179.1 - 3.8e-16 59.4 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 PVD25179.1 - 0.00059 19.9 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PVD25179.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain D123 PF07065.14 PVD25180.1 - 1e-95 320.4 0.0 1.2e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 PVD25180.1 - 3e-05 24.1 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 PVD25180.1 - 8.7e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 DUF5372 PF17342.2 PVD25180.1 - 0.0035 17.7 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5372) SNF PF00209.18 PVD25181.1 - 1.1e-200 667.8 28.2 1.8e-200 667.1 28.2 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family wnt PF00110.19 PVD25183.1 - 7.1e-61 206.5 23.8 7.9e-61 206.3 23.8 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 PVD25186.1 - 6.2e-54 183.7 1.2 7.4e-54 183.4 1.2 1.0 1 0 0 1 1 1 1 wnt family Sushi PF00084.20 PVD25188.1 - 5.2e-17 62.2 24.6 1.1e-05 25.9 0.3 6.4 7 0 0 7 7 7 4 Sushi repeat (SCR repeat) Trypsin PF00089.26 PVD25188.1 - 9.8e-07 28.8 0.2 8.6e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 Trypsin HRM PF02793.22 PVD25188.1 - 0.0084 16.4 1.5 0.0084 16.4 1.5 3.5 4 0 0 4 4 4 1 Hormone receptor domain LRR_4 PF12799.7 PVD25189.1 - 1.7e-16 60.1 18.0 2.5e-06 27.7 0.2 5.0 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD25189.1 - 2.5e-10 40.0 18.7 1.2e-06 28.2 7.1 4.6 4 1 1 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 PVD25189.1 - 3.7e-10 39.6 3.2 2.2e-05 24.1 0.7 2.7 1 1 1 2 2 2 2 Leucine-rich repeat PX PF00787.24 PVD25189.1 - 2.6e-06 27.4 0.2 6.9e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 PX domain LRR_6 PF13516.6 PVD25189.1 - 0.014 15.4 10.8 13 6.2 1.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_hydro_20 PF00728.22 PVD25190.1 - 4.1e-98 329.0 0.0 6.1e-98 328.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SNF PF00209.18 PVD25190.1 - 5e-52 177.3 31.1 6.3e-32 111.0 9.0 2.2 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family CHB_HEX PF03173.13 PVD25190.1 - 3.4e-25 88.6 0.0 1.5e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 PVD25190.1 - 8.6e-21 73.7 0.1 5.2e-20 71.2 0.0 2.4 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 PVD25190.1 - 1.2e-11 45.4 0.0 2.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 LZ_Tnp_IS66 PF13007.7 PVD25190.1 - 0.024 15.4 0.1 0.053 14.3 0.1 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Glycohydro_20b2 PF14845.6 PVD25190.1 - 0.045 14.4 0.0 0.091 13.4 0.0 1.5 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Cep3 PF16846.5 PVD25190.1 - 0.082 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Ninjurin PF04923.12 PVD25190.1 - 0.18 11.8 1.4 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Ninjurin cNMP_binding PF00027.29 PVD25191.1 - 2.6e-06 27.4 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TMEM132D_C PF15706.5 PVD25192.1 - 1.6 8.5 3.6 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PDZ PF00595.24 PVD25193.1 - 9.3e-24 83.6 5.0 9.8e-15 54.7 0.8 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD25193.1 - 2e-15 56.4 1.7 1.1e-07 31.5 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PVD25193.1 - 1.6e-14 54.0 2.7 2.6e-08 34.1 0.1 2.8 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 PVD25193.1 - 3.5e-05 23.7 0.9 0.017 15.1 0.1 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 PVD25193.1 - 0.066 13.6 0.2 4.4 7.7 0.0 2.5 2 0 0 2 2 2 0 PDZ domain DUF1908 PF08926.11 PVD25193.1 - 5.6 6.0 8.5 0.87 8.6 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) PDZ PF00595.24 PVD25194.1 - 3.7e-13 49.6 0.0 3.9e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD25194.1 - 5.2e-10 39.0 0.1 0.00061 19.6 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PVD25194.1 - 2.4e-05 24.6 0.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Death PF00531.22 PVD25194.1 - 0.00033 20.7 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 Death domain DIX PF00778.17 PVD25194.1 - 0.019 14.8 1.0 0.25 11.2 0.0 3.1 4 0 0 4 4 4 0 DIX domain DUF4097 PF13349.6 PVD25195.1 - 3.3e-13 49.6 12.5 7.5e-09 35.3 5.9 3.1 1 1 0 2 2 2 2 Putative adhesin tRNA_m1G_MT PF01746.21 PVD25196.1 - 1.7e-24 86.6 0.0 4.3e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase tRNA_m1G_MT PF01746.21 PVD25197.1 - 4.6e-24 85.2 0.0 1.2e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ank_2 PF12796.7 PVD25198.1 - 1.8e-44 150.2 10.3 9.3e-16 58.2 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25198.1 - 1e-34 118.4 5.9 5.6e-09 36.4 0.2 6.1 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD25198.1 - 2.7e-32 109.8 12.5 4.6e-07 30.0 0.0 7.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 PVD25198.1 - 4.9e-32 106.4 1.0 0.0043 17.4 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 PVD25198.1 - 1.2e-31 108.3 2.5 1.7e-06 28.2 0.1 7.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) AnkUBD PF18418.1 PVD25198.1 - 0.15 12.2 0.0 3.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain Mito_carr PF00153.27 PVD25199.1 - 1.2e-52 175.8 0.4 3.2e-23 81.4 0.0 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 PVD25199.1 - 0.076 13.1 0.0 20 5.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) UCH PF00443.29 PVD25200.1 - 2e-67 227.4 0.2 3.3e-67 226.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 PVD25200.1 - 2.9e-23 81.6 0.3 7.2e-23 80.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 PVD25200.1 - 1.4e-22 80.1 1.1 7.4e-22 77.8 0.3 2.7 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 PVD25200.1 - 1.2e-14 54.6 1.4 3.7e-09 36.6 0.4 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 PVD25200.1 - 3e-10 40.2 0.1 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal DUF1461 PF07314.11 PVD25200.1 - 0.0014 18.6 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1461) SDA1 PF05285.12 PVD25200.1 - 5.3 6.4 12.7 8.7 5.7 12.7 1.3 1 0 0 1 1 1 0 SDA1 Ribosomal_S27e PF01667.17 PVD25200.1 - 9.6 6.0 6.2 0.54 10.0 0.5 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 Foamy_virus_ENV PF03408.14 PVD25201.1 - 0.058 11.2 1.2 0.069 11.0 1.2 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein EphA2_TM PF14575.6 PVD25201.1 - 0.24 12.3 0.8 0.44 11.5 0.8 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAP PF07174.11 PVD25201.1 - 0.76 9.2 16.2 0.99 8.8 16.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CH PF00307.31 PVD25204.1 - 2.4e-16 59.9 0.2 3.2e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD25204.1 - 0.0052 16.6 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain BDV_P24 PF06595.11 PVD25204.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus P24 protein cpYpsA PF12694.7 PVD25204.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Filamin PF00630.19 PVD25205.1 - 2.1e-170 555.3 29.5 6.4e-18 65.5 0.1 11.1 11 0 0 11 11 11 11 Filamin/ABP280 repeat CH PF00307.31 PVD25205.1 - 1e-13 51.4 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Y_Y_Y PF07495.13 PVD25205.1 - 1.5e-07 31.3 3.5 0.58 10.1 0.0 5.9 6 0 0 6 6 6 3 Y_Y_Y domain PapC_N PF13954.6 PVD25205.1 - 0.00059 19.9 0.2 3.8 7.5 0.0 3.8 4 0 0 4 4 4 2 PapC N-terminal domain YtkA PF13115.6 PVD25205.1 - 0.0011 19.5 3.1 1.6e+02 3.0 0.0 7.0 7 0 0 7 7 7 0 YtkA-like Big_3 PF07523.12 PVD25205.1 - 0.0013 19.0 18.5 3 8.2 0.1 9.0 9 1 1 10 10 10 1 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 PVD25205.1 - 0.0097 16.2 17.6 17 5.8 0.0 7.7 9 0 0 9 9 9 0 Invasin, domain 3 CarbopepD_reg_2 PF13715.6 PVD25205.1 - 0.011 15.7 0.5 2 8.5 0.0 3.9 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Glyco_hydro_64 PF16483.5 PVD25205.1 - 0.018 14.4 0.1 0.042 13.1 0.1 1.6 1 0 0 1 1 1 0 Beta-1,3-glucanase Cadherin_5 PF17892.1 PVD25205.1 - 0.044 13.7 1.8 4.7 7.3 0.1 4.0 4 0 0 4 4 4 0 Cadherin-like domain DUF4369 PF14289.6 PVD25205.1 - 0.051 14.1 0.1 0.28 11.7 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Big_6 PF17936.1 PVD25205.1 - 0.053 13.8 10.0 0.76 10.1 0.1 5.9 6 1 0 7 7 7 0 Bacterial Ig domain Big_3_5 PF16640.5 PVD25205.1 - 0.092 12.9 22.2 0.25 11.6 1.4 7.6 8 1 1 9 9 9 0 Bacterial Ig-like domain (group 3) Filamin PF00630.19 PVD25206.1 - 3.2e-114 374.8 14.3 1.6e-19 70.7 0.1 9.1 8 1 0 8 8 8 8 Filamin/ABP280 repeat Y_Y_Y PF07495.13 PVD25206.1 - 1.4e-11 44.2 0.6 0.51 10.3 0.0 6.6 7 0 0 7 7 7 4 Y_Y_Y domain YtkA PF13115.6 PVD25206.1 - 2.2e-05 25.0 0.2 9.9 6.9 0.0 5.8 6 0 0 6 6 6 2 YtkA-like DUF5060 PF16586.5 PVD25206.1 - 7.3e-05 23.1 0.0 49 4.4 0.0 6.6 8 0 0 8 8 8 0 Domain of unknown function (DUF5060) EMP24_GP25L PF01105.24 PVD25206.1 - 0.038 13.9 0.2 10 6.0 0.0 4.6 6 1 2 8 8 8 0 emp24/gp25L/p24 family/GOLD ISAV_HA PF06215.11 PVD25206.1 - 0.11 11.7 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin TruD PF01142.18 PVD25207.1 - 6.9e-77 259.0 0.0 3.3e-72 243.6 0.0 2.8 2 2 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF3552 PF12072.8 PVD25208.1 - 2.7e-05 23.7 6.9 0.0064 15.9 1.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 PVD25208.1 - 0.0033 17.0 1.3 0.0049 16.5 1.3 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit LRR19-TM PF15176.6 PVD25208.1 - 0.052 13.5 2.0 0.77 9.8 2.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3450 PF11932.8 PVD25208.1 - 0.077 12.3 0.5 0.12 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 PVD25208.1 - 0.37 10.5 3.1 0.58 9.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Nup54 PF13874.6 PVD25208.1 - 0.42 10.7 5.6 0.96 9.6 5.6 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4472 PF14739.6 PVD25208.1 - 0.62 10.8 3.2 1.3 9.8 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) RGM_N PF06535.12 PVD25209.1 - 0.002 18.3 1.5 0.002 18.3 1.5 1.7 2 0 0 2 2 2 1 Repulsive guidance molecule (RGM) N-terminus Osteopontin PF00865.18 PVD25209.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Osteopontin CPG4 PF15481.6 PVD25209.1 - 4.5 8.0 12.0 0.1 13.2 2.8 2.4 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 tRNA-synt_1c PF00749.21 PVD25217.1 - 1.1e-112 376.0 0.0 2e-112 375.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PVD25217.1 - 8.6e-47 159.2 0.1 3.4e-46 157.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 PVD25217.1 - 1.2e-41 142.4 7.6 3.8e-21 75.8 1.5 2.4 1 1 1 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 PVD25217.1 - 9.8e-25 87.3 1.4 4.1e-24 85.3 1.4 2.1 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SurA_N PF09312.11 PVD25217.1 - 0.079 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Prp18 PF02840.15 PVD25218.1 - 3.4e-61 205.5 0.2 6.4e-61 204.6 0.2 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 PVD25218.1 - 1.7e-13 49.8 0.6 3.2e-13 49.0 0.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.6 PVD25218.1 - 0.0071 16.8 0.4 2.4 8.7 0.0 3.0 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain RHINO PF15319.6 PVD25218.1 - 0.035 14.2 1.1 0.072 13.1 1.1 1.4 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein ABC_tran PF00005.27 PVD25219.1 - 2.1e-34 119.0 0.0 3.2e-21 76.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PVD25219.1 - 1.8e-22 79.9 9.4 3e-22 79.2 9.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PVD25219.1 - 4.2e-12 46.5 0.2 2.1e-07 31.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PVD25219.1 - 0.0092 16.5 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 PVD25219.1 - 0.012 15.9 0.0 6.1 7.2 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.7 PVD25220.1 - 5.6e-17 61.9 16.6 7.1e-17 61.5 16.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 PVD25220.1 - 0.0017 17.7 11.8 0.0017 17.7 11.8 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 PVD25220.1 - 0.0017 17.8 14.6 0.0026 17.2 14.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter UPF0182 PF03699.13 PVD25220.1 - 1.3 7.1 8.5 1.6 6.8 8.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) IF4E PF01652.18 PVD25224.1 - 7.4e-43 146.1 0.3 9.5e-43 145.7 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IBR PF01485.21 PVD25225.1 - 3.7e-16 59.1 40.0 3e-10 40.1 9.3 4.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 PVD25225.1 - 0.0011 18.8 8.0 0.0011 18.8 8.0 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD25225.1 - 0.009 15.8 5.4 0.009 15.8 5.4 5.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD25225.1 - 0.011 16.0 6.4 0.011 16.0 6.4 4.1 3 0 0 3 3 3 0 Ring finger domain UQ_con PF00179.26 PVD25226.1 - 4e-07 29.8 0.0 6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 PVD25226.1 - 0.0092 16.3 0.2 0.01 16.1 0.2 1.4 1 0 0 1 1 1 1 Uteroglobin family Alginate_lyase PF05426.12 PVD25226.1 - 0.082 12.4 0.2 0.14 11.7 0.1 1.4 2 0 0 2 2 2 0 Alginate lyase zf-C3HC PF07967.13 PVD25227.1 - 5.1e-21 75.1 7.2 1.1e-17 64.4 0.5 2.6 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 PVD25227.1 - 6.5e-15 55.1 7.2 5e-14 52.2 1.1 3.0 3 1 0 3 3 3 2 Rsm1-like Yippee-Mis18 PF03226.14 PVD25227.1 - 0.14 12.4 2.3 3.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Kelch_6 PF13964.6 PVD25228.1 - 1.3e-28 98.3 8.0 8.2e-06 25.9 0.1 6.5 5 2 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PVD25228.1 - 2.4e-25 88.3 3.5 0.00053 20.2 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD25228.1 - 2.9e-25 88.0 6.0 4.9e-06 26.5 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD25228.1 - 2.6e-23 81.5 4.7 6.5e-05 22.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PVD25228.1 - 4.2e-23 80.7 4.3 1.9e-05 24.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD25228.1 - 1.3e-13 50.3 19.5 0.0021 18.0 0.1 7.7 6 2 0 6 6 6 5 Kelch motif Plexin_cytopl PF08337.12 PVD25229.1 - 8.7e-218 724.5 0.1 1.1e-217 724.1 0.1 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 PVD25229.1 - 1e-55 189.3 0.1 1.5e-55 188.7 0.1 1.3 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 PVD25229.1 - 3e-33 113.8 5.5 3.3e-07 30.3 0.1 6.7 7 0 0 7 7 7 4 IPT/TIG domain TIG_plexin PF17960.1 PVD25229.1 - 3.2e-20 71.9 0.3 1.3e-13 50.8 0.0 4.0 4 0 0 4 4 4 2 TIG domain PSI PF01437.25 PVD25229.1 - 4.6e-13 49.5 48.8 1.3e-07 32.1 12.6 3.7 3 0 0 3 3 3 3 Plexin repeat TIG_2 PF18020.1 PVD25229.1 - 2.5e-12 47.2 0.0 1.6e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 TIG domain found in plexin TGF_beta_GS PF08515.12 PVD25230.1 - 0.12 11.9 1.9 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif FAM176 PF14851.6 PVD25233.1 - 0.2 11.3 2.1 0.21 11.2 2.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF2299 PF10061.9 PVD25235.1 - 0.024 14.4 0.5 7.4 6.3 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) Glutaredoxin PF00462.24 PVD25235.1 - 0.33 11.2 1.8 0.86 9.9 0.2 2.4 2 1 1 3 3 3 0 Glutaredoxin YcgL PF05166.13 PVD25237.1 - 0.0021 18.3 0.1 2.9 8.3 0.0 2.4 2 0 0 2 2 2 2 YcgL domain KH_dom-like PF14714.6 PVD25238.1 - 0.042 14.2 0.3 0.088 13.1 0.3 1.6 1 1 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF3793 PF12672.7 PVD25239.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) GCS2 PF04107.13 PVD25240.1 - 0.15 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Usp PF00582.26 PVD25241.1 - 5.5e-24 85.3 0.0 6.8e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Fasciclin PF02469.22 PVD25242.1 - 1.2e-55 187.1 0.1 1.7e-27 96.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain C2 PF00168.30 PVD25243.1 - 4.6e-23 81.5 0.0 6.3e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain SecY PF00344.20 PVD25244.1 - 2e-78 263.8 11.5 2.6e-78 263.4 11.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 PVD25244.1 - 7.1e-18 64.2 0.3 2.2e-17 62.6 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p SdpI PF13630.6 PVD25244.1 - 0.059 13.5 0.3 0.059 13.5 0.3 3.9 5 1 0 5 5 5 0 SdpI/YhfL protein family TIP49 PF06068.13 PVD25245.1 - 3.5e-172 572.4 1.0 4.5e-172 572.1 1.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PVD25245.1 - 8e-23 80.4 0.3 2.9e-22 78.6 0.3 2.1 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PVD25245.1 - 6.8e-13 49.2 0.8 2.1e-08 34.6 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PVD25245.1 - 3.4e-11 43.1 0.3 2.2e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD25245.1 - 1.9e-06 28.2 0.2 0.023 15.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PVD25245.1 - 6.8e-05 22.9 0.1 0.0057 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD25245.1 - 9.7e-05 22.8 0.0 0.0007 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 PVD25245.1 - 0.00012 21.8 0.6 0.16 11.7 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 PVD25245.1 - 0.00053 20.5 0.0 0.0073 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PVD25245.1 - 0.00062 19.4 0.4 0.0024 17.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD25245.1 - 0.00096 19.5 3.4 0.024 14.9 3.4 2.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PVD25245.1 - 0.00096 18.6 0.2 0.063 12.6 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PVD25245.1 - 0.003 17.3 0.1 0.0099 15.6 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 PVD25245.1 - 0.0037 17.5 0.1 0.01 16.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PVD25245.1 - 0.0042 17.1 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD25245.1 - 0.0062 16.1 0.1 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 PVD25245.1 - 0.0086 16.1 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 PVD25245.1 - 0.0091 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 PVD25245.1 - 0.011 15.0 0.3 0.03 13.6 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 PVD25245.1 - 0.012 15.3 0.6 0.65 9.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PVD25245.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PVD25245.1 - 0.021 14.9 0.2 0.071 13.1 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PVD25245.1 - 0.021 15.0 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PVD25245.1 - 0.024 14.1 0.8 0.059 12.8 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 PVD25245.1 - 0.03 13.4 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 PVD25245.1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 PVD25245.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 PVD25245.1 - 0.097 12.8 0.1 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 PVD25245.1 - 0.14 12.6 1.0 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PVD25245.1 - 0.16 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Peptidase_M14 PF00246.24 PVD25247.1 - 6.2e-39 134.5 0.0 1e-38 133.8 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 PVD25247.1 - 2e-15 56.9 0.1 4e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Rho_Binding PF08912.11 PVD25249.1 - 0.2 12.5 6.4 0.41 11.5 5.4 2.2 1 1 0 1 1 1 0 Rho Binding DUF1664 PF07889.12 PVD25249.1 - 0.98 9.5 4.8 1.6 8.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YlqD PF11068.8 PVD25249.1 - 3.2 8.1 12.1 21 5.5 8.7 2.1 2 0 0 2 2 2 0 YlqD protein DUF1499 PF07386.11 PVD25250.1 - 1.2 9.7 8.3 0.22 12.1 3.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1499) DUF4549 PF15082.6 PVD25251.1 - 2.9e-53 179.5 2.9 8.5e-53 178.0 2.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) Kinesin PF00225.23 PVD25252.1 - 2.1e-97 326.0 3.9 2.2e-97 326.0 2.7 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD25252.1 - 4.4e-36 124.0 0.8 4.4e-36 124.0 0.8 2.1 2 1 0 2 2 2 1 Microtubule binding ArlS_N PF18719.1 PVD25252.1 - 0.0043 17.3 0.3 0.0043 17.3 0.3 2.8 3 0 0 3 3 3 1 ArlS sensor domain APG6_N PF17675.1 PVD25252.1 - 0.01 16.4 1.1 0.01 16.4 1.1 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF1296 PF06972.11 PVD25252.1 - 0.027 14.6 0.9 0.17 12.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) TolA_bind_tri PF16331.5 PVD25252.1 - 1.4 9.0 10.8 0.58 10.3 4.8 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation LMBR1 PF04791.16 PVD25252.1 - 2 7.2 6.0 3.5 6.4 6.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Lzipper-MIP1 PF14389.6 PVD25252.1 - 2.5 8.5 9.9 0.12 12.7 3.0 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 IFT46_B_C PF12317.8 PVD25252.1 - 3.2 7.4 9.0 0.34 10.6 1.9 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal ACCA PF03255.14 PVD25252.1 - 3.8 7.4 14.2 1.1 9.1 5.0 3.1 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GIDA_assoc PF13932.6 PVD25252.1 - 6.6 6.9 15.3 1.4 9.0 10.7 2.1 2 0 0 2 2 2 0 GidA associated domain Filament PF00038.21 PVD25252.1 - 7.2 6.1 25.3 0.037 13.6 9.2 2.7 2 1 0 3 3 3 0 Intermediate filament protein Abhydrolase_1 PF00561.20 PVD25253.1 - 2.2e-24 86.5 0.5 2.8e-18 66.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD25253.1 - 8.5e-18 65.8 0.6 1.1e-14 55.6 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD25253.1 - 5.1e-09 35.8 0.4 3.3e-05 23.3 0.2 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 PVD25253.1 - 0.0026 16.5 0.0 0.04 12.6 0.0 2.0 1 1 1 2 2 2 1 Ndr family DUF2048 PF09752.9 PVD25253.1 - 0.0051 16.0 0.1 0.0078 15.3 0.1 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Esterase_phd PF10503.9 PVD25253.1 - 0.0086 15.6 0.1 0.065 12.7 0.1 2.3 2 1 0 2 2 2 1 Esterase PHB depolymerase BAAT_C PF08840.11 PVD25253.1 - 0.01 15.7 0.2 0.077 12.9 0.1 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 PVD25253.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 PVD25253.1 - 0.05 12.3 0.0 0.54 8.9 0.0 2.0 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PVD25253.1 - 0.051 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 PVD25253.1 - 0.055 13.0 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family DFF-C PF09033.10 PVD25254.1 - 1.8e-14 54.0 1.3 1.9e-14 53.9 1.3 1.0 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain Kelch_1 PF01344.25 PVD25255.1 - 4.4e-34 115.8 8.0 1.2e-11 44.0 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PVD25255.1 - 3.2e-28 97.0 0.8 1.8e-07 31.2 0.0 4.5 3 1 1 4 4 4 4 Kelch motif BTB PF00651.31 PVD25255.1 - 5.4e-27 94.2 4.1 1e-26 93.3 2.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD25255.1 - 3.2e-19 68.9 1.7 2.7e-18 66.0 0.3 2.5 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD25255.1 - 2.1e-14 53.4 3.0 5e-05 23.5 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD25255.1 - 1.5e-09 37.4 1.4 0.26 11.3 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PVD25255.1 - 1.1e-06 28.4 0.2 0.62 10.1 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 PVD25255.1 - 1.3e-05 25.1 2.5 0.0052 16.8 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Abhydrolase_1 PF00561.20 PVD25257.1 - 1.7e-14 54.1 0.1 2.6e-14 53.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD25257.1 - 1.4e-12 48.7 0.0 1.8e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD25257.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Vta1 PF04652.16 PVD25257.1 - 0.022 14.7 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Vta1 like HypD PF01924.16 PVD25257.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Glyco_transf_4 PF13439.6 PVD25257.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Kelch_1 PF01344.25 PVD25258.1 - 5.5e-07 29.1 0.1 0.00055 19.5 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 PVD25258.1 - 0.00068 19.8 0.2 0.0023 18.1 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 PVD25258.1 - 0.016 15.5 0.0 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain DFF-C PF09033.10 PVD25259.1 - 1.8e-20 73.5 0.7 2.1e-20 73.3 0.7 1.1 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain Kelch_1 PF01344.25 PVD25260.1 - 4.2e-37 125.5 7.9 9.7e-12 44.3 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PVD25260.1 - 6.5e-29 99.2 0.8 1.5e-07 31.4 0.0 4.4 3 1 1 4 4 4 4 Kelch motif BTB PF00651.31 PVD25260.1 - 2.4e-27 95.4 1.9 4.7e-27 94.4 1.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 PVD25260.1 - 1.5e-15 57.0 2.1 4.1e-05 23.7 0.1 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD25260.1 - 4.4e-10 39.1 1.2 0.22 11.6 0.0 5.4 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PVD25260.1 - 5.7e-07 29.4 0.1 0.51 10.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 PVD25260.1 - 0.00027 20.9 8.2 0.0043 17.0 0.0 5.1 6 0 0 6 6 6 1 Galactose oxidase, central domain BACK PF07707.15 PVD25260.1 - 0.0015 18.6 0.2 0.028 14.5 0.1 2.5 1 1 2 3 3 3 1 BTB And C-terminal Kelch MITF_TFEB_C_3_N PF15951.5 PVD25261.1 - 0.021 15.5 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus GST_N PF02798.20 PVD25262.1 - 2.3e-09 37.4 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD25262.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD25262.1 - 0.016 15.9 0.0 0.04 14.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 PVD25263.1 - 6.2e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD25263.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD25263.1 - 0.0018 19.0 0.0 0.0028 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 PVD25263.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PRP4 PF08799.11 PVD25263.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GST_C_3 PF14497.6 PVD25264.1 - 4.8e-21 74.8 0.1 7.4e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD25264.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD25264.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD25264.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PVD25264.1 - 0.082 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PVD25264.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD25265.1 - 3.8e-22 78.3 0.1 5.2e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD25265.1 - 6.9e-06 26.3 0.1 3.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD25265.1 - 0.00012 22.2 0.1 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD25265.1 - 0.00054 19.9 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD25265.1 - 0.036 14.8 0.0 0.064 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 PVD25265.1 - 0.055 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Usp PF00582.26 PVD25266.1 - 5e-15 56.3 0.1 6.9e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family UPF0515 PF15135.6 PVD25268.1 - 4.4e-17 62.3 1.2 2.4e-08 33.7 0.9 2.0 1 1 1 2 2 2 2 Uncharacterised protein UPF0515 zf-3CxxC_2 PF17180.4 PVD25268.1 - 0.043 14.6 0.0 0.064 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding domain UPF0515 PF15135.6 PVD25269.1 - 1.4e-23 83.6 2.9 2.1e-14 53.5 0.8 2.7 2 1 1 3 3 3 2 Uncharacterised protein UPF0515 ALF PF03752.13 PVD25269.1 - 0.0078 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Short repeats of unknown function UPF0515 PF15135.6 PVD25270.1 - 1.9e-23 83.2 0.1 1.9e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 Usp PF00582.26 PVD25271.1 - 1.3e-21 77.6 0.1 1.7e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family YdjC PF04794.12 PVD25271.1 - 0.054 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 YdjC-like protein YtxH PF12732.7 PVD25271.1 - 0.18 12.4 0.0 0.18 12.4 0.0 1.6 2 0 0 2 2 2 0 YtxH-like protein Usp PF00582.26 PVD25272.1 - 8.6e-18 65.2 0.0 9.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family SUKH-3 PF14433.6 PVD25272.1 - 0.067 13.7 0.1 0.083 13.3 0.1 1.1 1 0 0 1 1 1 0 SUKH-3 immunity protein PAN_1 PF00024.26 PVD25273.1 - 0.0026 17.7 6.4 0.003 17.5 1.5 2.3 2 0 0 2 2 2 1 PAN domain Gemin7 PF11095.8 PVD25273.1 - 0.08 12.8 0.0 18 5.3 0.0 2.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) PAN_4 PF14295.6 PVD25273.1 - 0.092 12.7 1.4 0.25 11.3 1.4 1.8 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 PVD25275.1 - 3.9e-05 23.5 2.1 7.1e-05 22.7 2.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD25275.1 - 0.049 13.5 3.5 0.13 12.2 3.5 1.7 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 PVD25275.1 - 0.28 11.3 3.4 0.63 10.2 3.4 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 PVD25276.1 - 0.00021 21.2 2.8 0.0004 20.3 2.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD25276.1 - 0.32 10.9 5.4 0.69 9.9 5.4 1.5 1 0 0 1 1 1 0 PAN domain EF-hand_7 PF13499.6 PVD25277.1 - 3e-05 24.4 1.6 6.8e-05 23.2 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD25277.1 - 0.002 17.9 0.1 0.0088 15.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain TMEM43 PF07787.12 PVD25278.1 - 6.7e-54 182.9 3.2 9.2e-52 175.9 3.2 2.4 1 1 0 1 1 1 1 Transmembrane protein 43 TPH PF13868.6 PVD25279.1 - 0.00038 19.1 16.6 0.00053 18.6 16.6 1.2 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Atg14 PF10186.9 PVD25279.1 - 0.47 9.5 5.0 0.73 8.9 5.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RseA_C PF03873.13 PVD25279.1 - 0.66 10.2 8.0 0.28 11.4 3.0 2.8 2 1 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Y_phosphatase PF00102.27 PVD25280.1 - 7.8e-77 258.0 0.3 7.6e-25 87.8 0.0 4.2 4 0 0 4 4 4 4 Protein-tyrosine phosphatase DSPc PF00782.20 PVD25280.1 - 0.0019 18.0 0.0 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD25280.1 - 0.022 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GRA6 PF05084.13 PVD25281.1 - 0.013 15.5 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Y_phosphatase PF00102.27 PVD25282.1 - 8.2e-160 529.6 32.1 7e-41 140.3 6.5 10.2 7 2 1 8 8 8 8 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 PVD25282.1 - 3.5e-07 30.4 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 2 F5/8 type C domain TMEM154 PF15102.6 PVD25282.1 - 0.00027 20.9 1.7 0.82 9.6 0.4 2.8 2 0 0 2 2 2 2 TMEM154 protein family SCP_3 PF17844.1 PVD25282.1 - 0.012 15.3 5.7 2.7 7.8 0.1 3.6 3 0 0 3 3 3 0 Bacterial SCP ortholog DUF5456 PF17539.2 PVD25282.1 - 0.022 14.6 0.1 44 3.9 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5456) EphA2_TM PF14575.6 PVD25282.1 - 0.024 15.5 0.0 11 7.0 0.0 3.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PAP2 PF01569.21 PVD25282.1 - 0.057 13.2 0.2 17 5.2 0.1 2.8 2 0 0 2 2 2 0 PAP2 superfamily Y_phosphatase PF00102.27 PVD25283.1 - 1.9e-66 224.0 5.3 3.6e-44 151.1 0.7 2.7 2 1 1 3 3 3 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 PVD25283.1 - 7.7e-06 26.0 0.2 1.8e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 F5/8 type C domain SKG6 PF08693.10 PVD25283.1 - 0.095 12.1 6.2 0.18 11.3 6.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F5_F8_type_C PF00754.25 PVD25285.1 - 0.00011 22.4 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 PVD25286.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Yeast_MT PF11403.8 PVD25286.1 - 0.022 15.3 10.8 0.022 15.3 10.8 13.7 10 3 3 14 14 14 0 Yeast metallothionein rve_3 PF13683.6 PVD25286.1 - 0.073 12.9 0.0 10 6.0 0.0 3.1 3 0 0 3 3 3 0 Integrase core domain DUF5497 PF17601.2 PVD25286.1 - 0.2 12.0 0.2 33 4.9 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5497) DEFB136 PF17333.2 PVD25286.1 - 2.9 7.9 87.5 3.2 7.8 3.9 11.2 10 0 0 10 10 10 0 Beta defensin 136 F5_F8_type_C PF00754.25 PVD25287.1 - 2.7e-05 24.3 6.5 0.39 10.8 0.0 4.1 4 1 0 4 4 4 2 F5/8 type C domain Imm41 PF15592.6 PVD25287.1 - 0.14 12.5 3.7 36 4.7 0.1 3.2 3 0 0 3 3 3 0 Immunity protein 41 Ldl_recept_a PF00057.18 PVD25289.1 - 0.016 15.4 4.6 0.056 13.7 4.6 2.0 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF3377 PF11857.8 PVD25289.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) WBP-1 PF11669.8 PVD25289.1 - 0.069 13.8 0.0 0.2 12.3 0.0 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF515 PF04415.12 PVD25290.1 - 0.028 12.8 0.1 0.044 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SAP PF02037.27 PVD25291.1 - 9.2e-07 28.5 0.0 2.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 SAP domain Tim17 PF02466.19 PVD25292.1 - 4.6e-28 97.8 4.5 6.4e-28 97.4 4.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Shisa PF13908.6 PVD25293.1 - 0.21 11.8 0.0 0.24 11.6 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator VWA_CoxE PF05762.14 PVD25294.1 - 2.5e-05 23.8 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein FoP_duplication PF13865.6 PVD25294.1 - 6.5 7.4 7.7 12 6.5 7.7 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ARPC4 PF05856.12 PVD25295.1 - 1.2e-58 197.4 9.3 2.3e-43 147.7 4.4 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) Cadherin-like PF12733.7 PVD25296.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain Terminase_GpA PF05876.12 PVD25296.1 - 0.17 10.4 1.6 0.32 9.5 1.6 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) LRRFIP PF09738.9 PVD25298.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 LRRFIP family CCDC92 PF14916.6 PVD25299.1 - 0.19 11.5 2.7 0.94 9.3 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF4371 PF14291.6 PVD25300.1 - 2.9e-07 30.4 0.1 7.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4371) RVT_1 PF00078.27 PVD25301.1 - 1.1e-05 25.1 0.1 2e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CreA PF05981.12 PVD25301.1 - 0.022 14.7 1.4 4.9 7.1 0.0 2.2 1 1 1 2 2 2 0 CreA protein RVT_1 PF00078.27 PVD25302.1 - 5e-07 29.5 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2511 PF10709.9 PVD25302.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) Glyco_transf_10 PF00852.19 PVD25306.1 - 2.7e-36 124.9 0.0 1.3e-35 122.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD25306.1 - 3e-18 66.3 0.0 5.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal BaffR-Tall_bind PF09256.10 PVD25306.1 - 0.039 13.7 0.7 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Glyco_transf_10 PF00852.19 PVD25307.1 - 1.7e-51 174.5 0.0 2.4e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD25307.1 - 3.4e-21 75.8 0.0 7e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal 6PF2K PF01591.18 PVD25308.1 - 1.2e-80 270.0 0.1 1.7e-80 269.5 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PVD25308.1 - 2.4e-43 148.1 0.0 4e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 PVD25308.1 - 8e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PVD25308.1 - 0.046 13.0 0.0 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 PVD25308.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Baculo_VP91_N PF08475.10 PVD25309.1 - 0.027 14.2 0.3 0.043 13.5 0.3 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal F-box-like_2 PF13013.6 PVD25310.1 - 0.043 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Rif1_N PF12231.8 PVD25310.1 - 0.09 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Laminin_G_3 PF13385.6 PVD25311.1 - 7.6e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PVD25311.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Med20 PF08612.11 PVD25312.1 - 1.7e-43 148.6 0.0 2e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF4838 PF16126.5 PVD25312.1 - 0.02 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Pkinase PF00069.25 PVD25313.1 - 2.3e-28 99.3 0.0 5.3e-21 75.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25313.1 - 0.0047 16.2 0.1 1.2 8.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DUF4990 PF16380.5 PVD25313.1 - 0.093 12.8 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function LSM PF01423.22 PVD25316.1 - 9.1e-16 57.3 0.8 1.2e-15 57.0 0.8 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L2_C PF03947.18 PVD25317.1 - 1.1e-31 109.7 0.2 1.1e-31 109.7 0.2 2.2 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PVD25317.1 - 1.4e-23 82.6 0.2 2.7e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CBM_14 PF01607.24 PVD25318.1 - 1.1e-11 44.7 15.6 0.00015 21.8 0.2 3.5 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD25319.1 - 7e-20 70.9 12.6 2.4e-06 27.6 0.5 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 PVD25319.1 - 0.48 8.4 1.1 1 7.4 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Pkinase PF00069.25 PVD25320.1 - 2.1e-44 151.9 0.0 6.9e-44 150.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25320.1 - 1.6e-27 96.4 0.0 1.1e-26 93.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD25320.1 - 2.2e-06 27.2 0.0 7.2e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD25320.1 - 0.003 17.5 0.7 0.33 10.9 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family DUF4011 PF13195.6 PVD25320.1 - 0.0047 16.9 1.8 0.042 13.8 1.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4011) Pkinase_fungal PF17667.1 PVD25320.1 - 0.022 13.6 1.6 0.058 12.2 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase Guanylate_kin PF00625.21 PVD25320.1 - 0.11 12.1 2.5 1.2 8.8 0.1 2.5 1 1 1 2 2 2 0 Guanylate kinase Med9 PF07544.13 PVD25320.1 - 0.35 11.0 5.0 0.44 10.7 0.1 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Acyl-CoA_dh_1 PF00441.24 PVD25321.1 - 3e-40 137.9 0.4 2.6e-37 128.3 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PVD25321.1 - 2.6e-26 91.7 0.1 4.9e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD25321.1 - 3.5e-20 72.7 0.0 9.9e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD25321.1 - 1.1e-12 48.3 0.0 1.3e-11 44.9 0.0 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Tmemb_9 PF05434.11 PVD25322.1 - 0.039 13.9 1.8 0.051 13.5 1.8 1.2 1 0 0 1 1 1 0 TMEM9 Pex24p PF06398.11 PVD25322.1 - 0.045 12.7 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF5313 PF17240.2 PVD25322.1 - 0.13 12.7 2.5 0.17 12.3 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Anoctamin PF04547.12 PVD25322.1 - 0.17 10.7 0.2 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Phlebovirus_G2 PF07245.11 PVD25322.1 - 0.25 9.8 2.4 0.32 9.4 2.4 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 DUF929 PF06053.11 PVD25322.1 - 2.4 7.4 3.9 3.8 6.7 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3357 PF11837.8 PVD25322.1 - 8.9 6.8 7.4 78 3.8 7.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1877 PF08974.10 PVD25323.1 - 4.8 7.2 8.6 1.6 8.8 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) Ank_2 PF12796.7 PVD25324.1 - 1.3e-16 60.9 0.0 5.8e-07 30.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.31 PVD25324.1 - 3.1e-16 59.3 16.8 4.7e-16 58.8 16.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 PVD25324.1 - 7.1e-15 53.6 0.6 0.00013 22.1 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PVD25324.1 - 4.6e-14 52.1 0.4 2.8e-05 24.4 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PVD25324.1 - 2e-12 47.1 1.1 0.0015 18.8 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD25324.1 - 1.3e-11 44.8 0.2 0.00015 22.2 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 PVD25324.1 - 6.5e-09 35.0 15.6 7.2e-09 34.8 9.5 2.8 2 1 1 3 3 3 1 Polycystin cation channel COX7B PF05392.11 PVD25324.1 - 0.064 12.9 0.4 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Bac_export_2 PF01312.19 PVD25324.1 - 0.31 10.2 4.1 0.11 11.7 1.2 1.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Glyco_transf_43 PF03360.16 PVD25326.1 - 4.4e-70 235.7 0.0 3.2e-50 170.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 43 Glyco_transf_43 PF03360.16 PVD25327.1 - 6.3e-48 163.3 0.0 8e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 Methyltransf_21 PF05050.12 PVD25328.1 - 1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Tetraspanin PF00335.20 PVD25329.1 - 3.3e-21 76.1 7.2 2.7e-16 60.0 0.7 2.1 2 0 0 2 2 2 2 Tetraspanin family 7tm_1 PF00001.21 PVD25330.1 - 3.7e-17 62.5 0.0 5.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD25330.1 - 0.017 14.5 0.1 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 PVD25330.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx BSD PF03909.17 PVD25330.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 BSD domain Fasciclin PF02469.22 PVD25331.1 - 5.3e-45 152.8 0.2 9.7e-25 87.3 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain RexB PF15968.5 PVD25331.1 - 0.0017 18.8 0.1 0.0041 17.6 0.1 1.6 1 0 0 1 1 1 1 Membrane-anchored ion channel, Abi component ANF_receptor PF01094.28 PVD25332.1 - 8.1e-77 258.7 0.2 9.3e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD25332.1 - 4e-25 89.2 0.2 1.4e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein TMEM52 PF14979.6 PVD25332.1 - 0.077 12.9 0.4 0.33 10.9 0.4 2.1 1 0 0 1 1 1 0 Transmembrane 52 Rsc14 PF08586.10 PVD25332.1 - 1.1 10.1 3.6 7.4 7.4 2.0 2.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit HNOB PF07700.15 PVD25333.1 - 0.00012 22.1 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 Haem-NO-binding Guanylate_cyc PF00211.20 PVD25334.1 - 2.7e-44 151.0 0.6 2.4e-31 108.8 0.1 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD25334.1 - 4.1e-27 95.0 1.4 6e-27 94.5 1.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated HNOBA PF07701.14 PVD25335.1 - 1.8e-14 53.7 0.0 2.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 PVD25336.1 - 7.2e-64 214.8 0.0 1.1e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD25336.1 - 1.1e-26 93.7 2.4 1.6e-26 93.1 2.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated Ribosomal_L24e PF01246.20 PVD25338.1 - 3e-30 104.2 6.4 5.2e-30 103.5 6.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e tRNA-synt_2b PF00587.25 PVD25339.1 - 9.4e-40 136.5 0.2 1.9e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PVD25339.1 - 2.2e-17 63.2 2.6 2.2e-17 63.2 2.6 3.6 3 1 1 4 4 4 2 Seryl-tRNA synthetase N-terminal domain GCP_N_terminal PF17681.1 PVD25340.1 - 9.5e-35 120.7 0.2 4.2e-34 118.6 0.1 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 PVD25340.1 - 7.3e-32 111.0 16.9 2.3e-31 109.4 4.2 2.9 2 1 1 3 3 3 2 Gamma tubulin complex component C-terminal DUF1992 PF09350.10 PVD25340.1 - 0.69 10.1 3.9 1.8 8.8 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) DUF2939 PF11159.8 PVD25340.1 - 0.75 10.3 3.6 12 6.4 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Cofilin_ADF PF00241.20 PVD25341.1 - 1.6e-26 92.5 0.1 3.1e-23 81.9 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein HMG_box_2 PF09011.10 PVD25342.1 - 5.2e-34 116.7 17.4 3e-20 72.6 7.9 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 PVD25342.1 - 9.2e-30 102.9 14.9 1.8e-15 57.1 1.8 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.6 PVD25342.1 - 0.0091 16.0 14.8 0.025 14.6 2.9 2.8 1 1 1 2 2 2 2 HMG (high mobility group) box 5 MTBP_N PF14918.6 PVD25342.1 - 0.04 13.4 0.2 0.04 13.4 0.2 1.7 2 0 0 2 2 2 0 MDM2-binding Nore1-SARAH PF16517.5 PVD25343.1 - 1.1e-14 54.0 1.8 3.2e-14 52.5 1.8 1.9 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 PVD25343.1 - 1.5e-14 54.4 0.2 3.2e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 PVD25343.1 - 2.3e-12 46.6 11.2 4.8e-12 45.6 11.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 PVD25343.1 - 0.0035 17.7 0.1 0.0087 16.4 0.1 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 DUF4595 PF15283.6 PVD25343.1 - 0.13 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Pex26 PF07163.12 PVD25344.1 - 1.1e-33 116.9 0.5 1.2e-33 116.7 0.5 1.1 1 0 0 1 1 1 1 Pex26 protein TPR_MLP1_2 PF07926.12 PVD25345.1 - 0.00078 19.5 14.9 0.00078 19.5 14.9 7.7 2 1 6 8 8 8 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 PVD25345.1 - 0.0016 18.5 5.3 0.0016 18.5 5.3 9.0 3 2 6 9 9 9 5 Afadin- and alpha -actinin-Binding DUF2433 PF10360.9 PVD25345.1 - 9.8 6.3 6.8 3.4 7.8 1.2 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF2433) RRM_1 PF00076.22 PVD25346.1 - 3.7e-21 74.7 0.1 7.2e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD25346.1 - 4.5e-08 32.7 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PVD25346.1 - 2.8e-05 24.0 2.8 4.7e-05 23.3 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 PVD25346.1 - 0.00014 21.7 0.9 0.00027 20.9 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_8 PF11835.8 PVD25346.1 - 0.00076 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 RRM-like domain DNA_topoisoIV PF00521.20 PVD25346.1 - 0.0033 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A RRM_7 PF16367.5 PVD25346.1 - 0.0061 16.7 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_Rrp7 PF17799.1 PVD25346.1 - 0.017 15.0 3.1 1.3 8.8 0.0 2.7 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 PVD25346.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RNA_bind PF08675.11 PVD25346.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 RNA binding domain SET_assoc PF11767.8 PVD25346.1 - 0.13 11.9 0.4 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 PVD25346.1 - 0.41 10.8 4.1 5.8 7.1 0.1 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Cadherin PF00028.17 PVD25347.1 - 5e-165 536.5 53.5 1.7e-20 73.2 0.1 12.6 13 0 0 13 13 13 12 Cadherin domain Cadherin_3 PF16184.5 PVD25347.1 - 4.1e-23 81.5 29.0 0.0056 16.7 0.0 11.8 12 2 1 13 13 13 8 Cadherin-like Cadherin_2 PF08266.12 PVD25347.1 - 6e-14 51.6 0.0 0.34 10.8 0.0 7.5 7 0 0 7 7 7 4 Cadherin-like Cadherin_4 PF17803.1 PVD25347.1 - 0.0035 17.9 4.0 0.0035 17.9 4.0 13.9 12 4 0 13 13 13 4 Bacterial cadherin-like domain DUF4115 PF13464.6 PVD25347.1 - 0.16 12.2 4.2 1.7 8.9 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4115) Cadherin PF00028.17 PVD25348.1 - 2.3e-51 172.2 8.1 4.4e-16 59.1 0.8 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 PVD25348.1 - 0.0016 18.2 0.0 1.9 8.4 0.0 3.9 5 0 0 5 5 5 1 Cadherin-like NOB1_Zn_bind PF08772.11 PVD25348.1 - 0.055 13.6 0.2 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF5050 PF16472.5 PVD25348.1 - 0.068 12.4 1.0 0.083 12.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) DUF1282 PF06930.12 PVD25348.1 - 0.1 12.3 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Ependymin PF00811.18 PVD25349.1 - 0.015 15.5 3.8 2.9 8.2 0.1 4.5 2 2 0 2 2 2 0 Ependymin Kelch_1 PF01344.25 PVD25350.1 - 1.7e-79 261.2 21.3 1.6e-15 56.4 0.4 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 PVD25350.1 - 2.4e-49 164.1 6.3 3.7e-08 33.4 0.0 6.3 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD25350.1 - 5.1e-33 111.8 8.3 7.8e-05 22.5 0.1 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 PVD25350.1 - 6.3e-32 109.7 1.1 1.2e-31 108.9 0.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD25350.1 - 6.4e-30 102.8 7.3 1.1e-05 25.5 0.0 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD25350.1 - 2.2e-29 101.2 6.2 0.00011 22.1 0.0 6.2 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 PVD25350.1 - 1.1e-12 48.1 0.2 4.2e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 PVD25350.1 - 4.3e-11 42.5 12.6 0.059 13.4 0.2 5.9 6 0 0 6 6 6 4 Kelch motif DUF1668 PF07893.13 PVD25350.1 - 3.4e-05 23.4 0.0 0.0048 16.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1668) Glyoxal_oxid_N PF07250.11 PVD25350.1 - 0.024 13.8 0.4 0.98 8.6 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 PVD25350.1 - 0.083 13.4 8.7 52 4.5 0.1 5.7 6 0 0 6 6 6 0 PQQ-like domain Exo_endo_phos PF03372.23 PVD25351.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UCH PF00443.29 PVD25352.1 - 7.9e-40 137.0 0.0 1.1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD25352.1 - 3.4e-07 30.2 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase E_Pc_C PF06752.12 PVD25352.1 - 0.99 9.5 6.3 0.52 10.4 3.1 2.1 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus DUF4743 PF15916.5 PVD25353.1 - 0.017 15.1 0.0 4.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4743) ITI_HC_C PF06668.12 PVD25354.1 - 1.9e-09 37.5 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Glu_syn_central PF04898.14 PVD25355.1 - 0.039 13.4 0.1 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain fn3 PF00041.21 PVD25356.1 - 8.1e-33 112.6 4.9 1e-10 41.8 0.0 4.7 5 0 0 5 5 5 4 Fibronectin type III domain V-set PF07686.17 PVD25356.1 - 2.8e-13 50.0 0.3 7.4e-13 48.6 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD25356.1 - 6.4e-11 42.2 0.1 2.9e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD25356.1 - 8.4e-10 39.1 0.1 3.6e-09 37.1 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD25356.1 - 9.6e-09 35.3 0.2 2.2e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD25356.1 - 1.4e-08 34.9 2.9 1e-07 32.2 1.1 3.0 2 1 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD25356.1 - 0.013 15.7 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 bMG10 PF17973.1 PVD25356.1 - 0.016 15.4 0.2 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Ig_4 PF16680.5 PVD25356.1 - 0.017 15.4 1.5 1.1 9.5 0.2 3.0 2 1 1 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 PVD25356.1 - 0.023 15.3 0.4 2.8 8.6 0.0 3.8 3 1 1 4 4 4 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 PVD25356.1 - 0.08 13.1 0.0 0.65 10.2 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III domain Y_Y_Y PF07495.13 PVD25356.1 - 0.098 12.6 0.0 7.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Y_Y_Y domain Ig_6 PF18452.1 PVD25356.1 - 0.15 11.6 0.0 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain zf-RING_6 PF14835.6 PVD25357.1 - 1.5 8.8 3.0 53 3.8 0.1 3.2 1 1 2 3 3 3 0 zf-RING of BARD1-type protein RNA_pol_Rpb1_R PF05001.13 PVD25358.1 - 4.6 7.8 19.9 15 6.2 0.8 4.8 1 1 4 5 5 5 0 RNA polymerase Rpb1 C-terminal repeat fn3 PF00041.21 PVD25359.1 - 2.8e-17 62.8 0.3 4.7e-11 42.9 0.3 2.3 1 1 1 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.17 PVD25359.1 - 0.0048 16.7 0.3 0.013 15.4 0.1 1.7 1 1 1 2 2 2 1 Tissue factor fn3 PF00041.21 PVD25360.1 - 6.8e-13 48.8 5.5 1.2e-07 32.0 1.0 2.6 2 1 0 2 2 2 2 Fibronectin type III domain DUF1416 PF07210.12 PVD25361.1 - 0.039 13.8 1.8 3.2 7.7 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1416) Gp58 PF07902.11 PVD25361.1 - 0.063 11.6 0.0 0.071 11.4 0.0 1.0 1 0 0 1 1 1 0 gp58-like protein Ribosomal_L17 PF01196.19 PVD25361.1 - 0.13 13.2 5.6 50 4.9 0.7 4.2 1 1 3 4 4 4 0 Ribosomal protein L17 DUF913 PF06025.12 PVD25362.1 - 0.66 8.9 7.0 1.1 8.2 7.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 PVD25362.1 - 3.7 6.2 14.4 4.5 6.0 14.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LAP1C PF05609.12 PVD25362.1 - 5.3 6.0 10.4 5.9 5.9 10.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 PVD25362.1 - 10 4.9 5.7 11 4.8 5.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2608 PF11019.8 PVD25363.1 - 0.0054 16.2 3.2 1.5 8.2 0.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2608) Sec20 PF03908.13 PVD25363.1 - 0.056 13.4 0.2 0.25 11.3 0.1 1.9 1 1 1 2 2 2 0 Sec20 Methyltransf_25 PF13649.6 PVD25363.1 - 0.09 13.5 0.2 0.13 13.0 0.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain Baculo_LEF-10 PF07206.11 PVD25363.1 - 9.2 6.5 8.6 11 6.3 1.2 2.6 1 1 1 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) 7tm_1 PF00001.21 PVD25364.1 - 1.1e-48 165.8 9.1 1.5e-48 165.4 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD25364.1 - 3.1e-06 26.8 9.2 1.1e-05 25.0 9.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD25364.1 - 1.6e-05 24.8 4.5 0.00011 22.0 4.5 2.0 1 1 0 1 1 1 1 Olfactory receptor PIG-F PF06699.11 PVD25364.1 - 0.078 13.1 7.7 0.017 15.3 3.5 2.0 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F Trypsin PF00089.26 PVD25365.1 - 1.4e-11 44.6 0.0 4.5e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD25365.1 - 2e-08 35.3 0.0 4.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Gemini_AC4_5_2 PF08464.10 PVD25365.1 - 0.0048 16.8 1.5 0.011 15.6 1.5 1.6 1 0 0 1 1 1 1 Geminivirus AC4/5 conserved region Peptidase_S46 PF10459.9 PVD25365.1 - 1.4 7.5 10.1 0.051 12.2 0.5 2.4 3 0 0 3 3 3 0 Peptidase S46 Mcm10 PF09332.11 PVD25366.1 - 1.7e-79 267.9 30.1 1.8e-75 254.6 18.7 2.2 1 1 1 2 2 2 2 Mcm10 replication factor BDV_P10 PF06515.11 PVD25366.1 - 0.037 14.0 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Borna disease virus P10 protein Zn-ribbon_8 PF09723.10 PVD25366.1 - 0.8 9.9 5.4 1.4 9.1 2.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 PVD25366.1 - 2.6 8.0 5.0 5.1 7.0 0.1 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-H2C2_2 PF13465.6 PVD25366.1 - 8.6 7.0 19.0 4.6 7.8 5.6 4.7 4 0 0 4 4 4 0 Zinc-finger double domain MIF4G PF02854.19 PVD25367.1 - 7.1e-63 212.1 3.5 8.2e-36 123.6 0.0 2.6 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 PVD25367.1 - 2.5e-32 112.4 0.9 2.5e-32 112.4 0.9 2.4 1 1 1 2 2 2 1 Up-frameshift suppressor 2 RT_RNaseH PF17917.1 PVD25368.1 - 3.7e-06 27.2 0.0 9.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD25369.1 - 2e-14 53.6 0.0 1.7e-13 50.6 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 PVD25369.1 - 0.00027 21.4 0.0 0.00056 20.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PVD25369.1 - 0.0019 18.8 0.0 0.0042 17.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 PVD25369.1 - 0.049 13.6 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase HH_signal PF01085.18 PVD25370.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Sushi PF00084.20 PVD25371.1 - 8.6e-09 35.9 22.9 8.1e-06 26.3 4.4 4.4 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) HH_signal PF01085.18 PVD25371.1 - 1.2e-07 31.5 0.0 2.9e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Hedgehog amino-terminal signalling domain ChitinaseA_N PF08329.10 PVD25371.1 - 5.9e-05 22.7 0.7 5.3 6.7 0.1 4.7 4 0 0 4 4 4 3 Chitinase A, N-terminal domain fn3 PF00041.21 PVD25371.1 - 0.0002 21.7 28.7 0.19 12.1 0.1 10.4 13 0 0 13 13 13 3 Fibronectin type III domain Big_3_2 PF12245.8 PVD25371.1 - 0.032 14.5 0.3 3.3 8.0 0.0 3.8 3 0 0 3 3 3 0 Bacterial Ig-like domain Imp-YgjV PF10688.9 PVD25372.1 - 0.38 10.6 1.7 0.85 9.4 0.1 2.0 1 1 0 2 2 2 0 Bacterial inner membrane protein Nrap_D6 PF17407.2 PVD25373.1 - 5.6e-13 49.3 0.0 1.8e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 Big_9 PF17963.1 PVD25373.1 - 1.8e-09 38.2 1.8 1.1e-08 35.7 0.2 3.4 2 0 0 2 2 1 1 Bacterial Ig domain PAN_1 PF00024.26 PVD25373.1 - 2.8e-05 24.0 1.0 9.7e-05 22.3 1.0 1.9 1 0 0 1 1 1 1 PAN domain Cadherin_4 PF17803.1 PVD25373.1 - 9.3e-05 23.0 4.4 0.00064 20.3 0.3 4.0 3 0 0 3 3 3 1 Bacterial cadherin-like domain PAN_4 PF14295.6 PVD25373.1 - 0.0094 15.8 0.3 0.035 14.0 0.3 2.0 1 0 0 1 1 1 1 PAN domain Big_3_3 PF13750.6 PVD25373.1 - 0.018 14.7 2.4 0.6 9.7 0.0 4.5 5 1 0 5 5 5 0 Bacterial Ig-like domain (group 3) PAN_2 PF08276.11 PVD25373.1 - 0.035 14.2 0.3 0.14 12.3 0.3 2.0 1 0 0 1 1 1 0 PAN-like domain Avian_gp85 PF03708.14 PVD25373.1 - 0.07 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Cadherin_5 PF17892.1 PVD25373.1 - 0.075 13.0 0.4 0.29 11.1 0.0 2.2 2 0 0 2 2 1 0 Cadherin-like domain AIP3 PF03915.13 PVD25373.1 - 0.24 10.5 3.5 0.47 9.5 3.5 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 DUF2369 PF10179.9 PVD25373.1 - 0.36 11.2 2.8 5.2 7.5 0.0 4.1 5 0 0 5 5 2 0 Uncharacterised conserved protein (DUF2369) DUF4618 PF15397.6 PVD25373.1 - 1.5 8.2 5.0 0.99 8.8 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Ank_5 PF13857.6 PVD25374.1 - 2.2e-23 82.0 4.2 1.2e-09 38.2 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD25374.1 - 2.5e-22 79.3 1.6 1.9e-16 60.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25374.1 - 6.5e-22 77.6 1.5 1.6e-07 31.7 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25374.1 - 1.4e-18 65.1 0.8 3.6e-06 26.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PVD25374.1 - 4.8e-16 58.4 2.3 0.0003 21.1 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat DDE_Tnp_4 PF13359.6 PVD25375.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TMCO5 PF14992.6 PVD25375.1 - 5.4 6.5 6.1 6.3 6.3 6.1 1.1 1 0 0 1 1 1 0 TMCO5 family Methyltransf_21 PF05050.12 PVD25376.1 - 0.00098 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 PVD25377.1 - 2.8e-06 27.4 0.0 2.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase FkbM domain Gly_transf_sug PF04488.15 PVD25379.1 - 4.7e-08 33.6 0.1 1.4e-07 32.0 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PVD25379.1 - 0.024 13.9 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DAG1 PF05454.11 PVD25380.1 - 1.6e-52 178.7 15.8 2.4e-35 122.4 11.4 2.7 2 1 1 3 3 3 2 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 PVD25380.1 - 3.5e-21 75.6 0.2 6.8e-21 74.6 0.2 1.5 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 RCR PF12273.8 PVD25380.1 - 0.0014 19.3 0.7 0.0014 19.3 0.7 2.2 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red PRIMA1 PF16101.5 PVD25380.1 - 0.031 14.3 0.6 0.031 14.3 0.6 3.3 4 0 0 4 4 4 0 Proline-rich membrane anchor 1 MLANA PF14991.6 PVD25380.1 - 0.032 14.5 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Syndecan PF01034.20 PVD25380.1 - 0.17 11.9 1.4 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain Proton_antipo_C PF01010.19 PVD25380.1 - 0.23 11.0 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus RIFIN PF02009.16 PVD25380.1 - 0.24 11.3 0.7 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Rifin Glyco_transf_43 PF03360.16 PVD25382.1 - 1.7e-28 99.9 0.0 4.9e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 43 Glyco_transf_43 PF03360.16 PVD25383.1 - 2.1e-42 145.3 0.0 2.7e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_43 PF03360.16 PVD25386.1 - 1.1e-38 133.1 0.0 4e-38 131.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 43 NUSAP PF16006.5 PVD25390.1 - 3.5e-26 92.6 23.7 3.5e-26 92.6 23.7 2.7 2 1 0 2 2 2 1 Nucleolar and spindle-associated protein C2 PF00168.30 PVD25391.1 - 1.4e-33 115.2 2.8 1.8e-23 82.8 0.2 4.3 4 0 0 4 4 4 2 C2 domain SMP_LBD PF17047.5 PVD25391.1 - 9.2e-06 25.2 0.6 0.48 9.9 0.0 3.4 3 0 0 3 3 3 3 Synaptotagmin-like mitochondrial-lipid-binding domain BTB PF00651.31 PVD25392.1 - 8.1e-24 84.0 0.1 8.4e-14 51.7 0.1 3.6 2 2 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 PVD25392.1 - 4.1e-07 30.0 1.7 7.3e-07 29.2 0.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch MoaC PF01967.21 PVD25393.1 - 4.4e-53 179.0 4.8 7.5e-53 178.3 4.8 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 PVD25393.1 - 1.6e-40 138.0 0.0 3e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PVD25393.1 - 4.7e-12 46.6 0.0 1.1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily RVT_1 PF00078.27 PVD25394.1 - 5.3e-27 94.8 0.0 1.4e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHH PF10283.9 PVD25394.1 - 6e-12 45.3 8.3 6e-12 45.3 8.3 2.1 2 0 0 2 2 2 1 PBZ domain FHA_2 PF17913.1 PVD25394.1 - 0.00085 19.5 0.0 0.028 14.7 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PVD25394.1 - 0.052 13.9 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 PVD25394.1 - 0.079 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 FHA domain Aldedh PF00171.22 PVD25395.1 - 2e-118 395.8 3.7 2.8e-82 276.7 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 PVD25395.1 - 0.051 12.6 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 PVD25396.1 - 2.7e-21 76.1 0.0 5.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25396.1 - 0.00032 20.1 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PTPS PF01242.19 PVD25396.1 - 0.66 10.0 4.2 0.93 9.5 0.2 2.8 3 0 0 3 3 3 0 6-pyruvoyl tetrahydropterin synthase Bclx_interact PF08945.10 PVD25398.1 - 0.00013 21.6 0.9 0.0003 20.5 0.9 1.6 1 0 0 1 1 1 1 Bcl-x interacting, BH3 domain Bcl-2_BAD PF10514.9 PVD25398.1 - 0.038 14.5 0.2 0.069 13.6 0.2 1.4 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD BMF PF15185.6 PVD25398.1 - 0.039 13.7 1.2 0.049 13.4 0.4 1.6 1 1 1 2 2 2 0 Bcl-2-modifying factor, apoptosis eIF3_N PF09440.10 PVD25399.1 - 0.07 13.6 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain YabA PF06156.13 PVD25399.1 - 0.097 13.3 0.6 0.17 12.5 0.6 1.6 1 1 0 1 1 1 0 Initiation control protein YabA PACT_coil_coil PF10495.9 PVD25399.1 - 0.11 13.0 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fmp27_WPPW PF10359.9 PVD25399.1 - 0.16 10.8 0.5 0.18 10.6 0.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V-SNARE_C PF12352.8 PVD25399.1 - 0.37 11.1 5.1 1.6 9.1 1.4 3.2 2 2 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DivIC PF04977.15 PVD25399.1 - 0.47 10.2 5.5 3.1 7.7 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 PVD25399.1 - 0.63 10.2 3.0 0.89 9.7 1.2 2.1 1 1 1 2 2 2 0 Sperm tail C-terminal domain Mononeg_mRNAcap PF14318.6 PVD25399.1 - 0.84 8.8 5.3 1.1 8.4 3.3 1.8 1 1 1 2 2 2 0 Mononegavirales mRNA-capping region V APG6_N PF17675.1 PVD25399.1 - 1.7 9.2 7.5 6.9 7.2 7.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region SHE3 PF17078.5 PVD25399.1 - 6 6.5 8.0 0.94 9.1 3.4 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 PVD25399.1 - 8.5 6.7 11.9 1.1 9.6 3.5 2.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF2400 PF09674.10 PVD25400.1 - 0.0022 18.0 1.5 0.25 11.3 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) Spc7 PF08317.11 PVD25400.1 - 0.0061 15.5 10.8 0.061 12.2 6.1 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein SKA1 PF07160.12 PVD25400.1 - 0.0081 16.0 3.1 0.0081 16.0 3.1 1.7 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 PVD25400.1 - 0.009 16.5 6.6 0.049 14.1 2.1 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PVD25400.1 - 0.011 15.8 8.4 0.11 12.6 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TelA PF05816.11 PVD25400.1 - 0.03 13.4 8.5 0.093 11.8 8.5 1.9 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF3216 PF11505.8 PVD25400.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3216) IFT57 PF10498.9 PVD25400.1 - 0.065 12.2 8.0 0.021 13.8 5.1 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3450 PF11932.8 PVD25400.1 - 0.084 12.2 7.3 0.024 13.9 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 PVD25400.1 - 0.1 12.5 11.9 1.6 8.7 5.4 3.2 2 1 2 4 4 4 0 Prefoldin subunit PMC2NT PF08066.12 PVD25400.1 - 0.12 13.0 5.1 0.26 12.0 1.0 2.3 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Tmemb_cc2 PF10267.9 PVD25400.1 - 0.2 10.7 10.8 0.31 10.1 10.8 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CENP-F_leu_zip PF10473.9 PVD25400.1 - 0.31 11.1 17.5 0.15 12.1 11.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 PVD25400.1 - 0.36 10.7 6.6 0.21 11.4 3.4 2.2 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.6 PVD25400.1 - 0.36 11.2 11.2 0.25 11.7 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ParB PF08775.10 PVD25400.1 - 0.38 11.2 4.6 7.7 7.0 0.9 2.7 2 1 0 2 2 2 0 ParB family I_LWEQ PF01608.17 PVD25400.1 - 0.39 11.0 9.1 0.26 11.5 5.6 2.0 1 1 1 2 2 2 0 I/LWEQ domain Exonuc_VII_L PF02601.15 PVD25400.1 - 0.47 10.0 5.8 0.57 9.7 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MctB PF11382.8 PVD25400.1 - 0.48 10.1 3.0 8.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Snapin_Pallidin PF14712.6 PVD25400.1 - 0.52 10.8 16.7 0.2 12.1 5.6 3.2 2 1 1 3 3 3 0 Snapin/Pallidin AAA_13 PF13166.6 PVD25400.1 - 0.61 8.7 6.8 0.85 8.2 6.8 1.3 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 PVD25400.1 - 0.76 9.7 8.5 2.6 8.0 8.5 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF883 PF05957.13 PVD25400.1 - 0.76 10.4 7.2 1.5 9.5 1.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Macoilin PF09726.9 PVD25400.1 - 0.81 8.2 8.5 0.8 8.2 8.5 1.0 1 0 0 1 1 1 0 Macoilin family AAA_23 PF13476.6 PVD25400.1 - 0.88 10.0 7.9 1.5 9.3 7.9 1.3 1 1 0 1 1 1 0 AAA domain DUF16 PF01519.16 PVD25400.1 - 1.3 9.5 9.6 0.89 10.1 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 PVD25400.1 - 1.4 9.1 13.8 0.59 10.3 8.4 2.2 2 0 0 2 2 2 0 Tropomyosin like Spc24 PF08286.11 PVD25400.1 - 1.9 8.8 12.5 0.44 10.8 5.7 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 PVD25400.1 - 1.9 7.6 7.9 0.84 8.8 5.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 PVD25400.1 - 1.9 8.2 7.8 1.3 8.8 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 PVD25400.1 - 3.9 8.2 10.6 1.1 10.0 5.2 2.2 1 1 0 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 PVD25400.1 - 4.6 7.3 14.8 1.4 9.0 9.7 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 PVD25400.1 - 4.8 7.8 12.7 2.6 8.7 5.7 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 CEP209_CC5 PF16574.5 PVD25400.1 - 4.8 7.3 14.1 1.5 9.0 5.0 2.5 2 1 1 3 3 2 0 Coiled-coil region of centrosome protein CE290 Cnn_1N PF07989.11 PVD25400.1 - 5.3 7.3 10.9 6.6 7.0 6.9 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3552 PF12072.8 PVD25400.1 - 7.6 5.9 13.8 4.3 6.7 9.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) UPF0242 PF06785.11 PVD25400.1 - 8.9 6.4 12.6 33 4.5 12.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 PVD25400.1 - 9.1 7.0 12.1 14 6.4 7.0 2.9 2 1 0 2 2 2 0 SlyX FUSC PF04632.12 PVD25400.1 - 9.5 4.6 6.0 13 4.2 6.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family MDMPI_C PF07398.11 PVD25401.1 - 0.2 12.5 5.5 0.84 10.5 5.5 1.9 1 1 0 1 1 1 0 MDMPI C-terminal domain Exo_endo_phos_2 PF14529.6 PVD25402.1 - 1.5e-11 44.2 0.0 3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD25402.1 - 9.8e-07 28.5 0.1 2.8e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaphilin PF15290.6 PVD25402.1 - 0.074 12.7 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp CHASE8 PF17152.4 PVD25402.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain Pellino PF04710.14 PVD25403.1 - 3.1e-86 289.7 1.3 1.6e-74 251.1 0.1 2.1 1 1 1 2 2 2 2 Pellino SprT-like PF10263.9 PVD25403.1 - 2.3e-29 101.5 0.0 4.6e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Pkinase PF00069.25 PVD25404.1 - 3.8e-33 115.0 0.0 6e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25404.1 - 2.2e-21 76.3 0.0 3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD25404.1 - 1.2e-05 24.3 0.5 3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PVD25404.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B56 PF01603.20 PVD25405.1 - 5e-196 651.6 8.7 6.1e-196 651.3 8.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 PVD25405.1 - 0.0011 18.9 5.7 0.019 14.9 0.3 2.9 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RIH_assoc PF08454.11 PVD25405.1 - 0.0079 16.0 0.4 4.6 7.1 0.0 2.6 2 0 0 2 2 2 2 RyR and IP3R Homology associated SBF2 PF12335.8 PVD25405.1 - 0.061 12.9 1.5 0.16 11.5 0.0 2.3 2 1 0 2 2 2 0 Myotubularin protein LRR_8 PF13855.6 PVD25406.1 - 2.8e-09 36.6 12.5 5.6e-06 26.0 5.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD25406.1 - 0.0001 22.6 4.3 0.11 12.9 0.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) E1_dh PF00676.20 PVD25407.1 - 2.6e-107 358.2 0.0 3.3e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PVD25407.1 - 0.0042 16.3 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 PVD25407.1 - 0.0066 16.3 0.1 0.047 13.5 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_C97 PF05903.14 PVD25408.1 - 1.9e-42 144.7 0.0 2.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 PVD25408.1 - 0.023 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase YxiJ PF14176.6 PVD25408.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein PhoQ_Sensor PF08918.10 PVD25408.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoQ Sensor Ras PF00071.22 PVD25409.1 - 2.9e-41 140.8 0.1 3.4e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25409.1 - 1e-27 96.7 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD25409.1 - 2.4e-13 49.9 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD25409.1 - 5.8e-06 25.8 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 PVD25409.1 - 1.9e-05 24.6 0.4 0.0037 17.1 0.1 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 PVD25409.1 - 2.8e-05 23.6 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD25409.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD25409.1 - 0.00029 20.4 0.0 0.0029 17.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 PVD25409.1 - 0.0053 16.5 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD25409.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 PVD25409.1 - 0.0098 16.2 0.0 0.025 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PVD25409.1 - 0.021 14.7 0.0 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 PVD25409.1 - 0.041 13.6 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 PVD25409.1 - 0.058 12.6 0.2 0.58 9.3 0.2 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DLIC PF05783.11 PVD25409.1 - 0.064 12.1 0.0 4.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 PVD25409.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 PVD25409.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF4706 PF15797.5 PVD25410.1 - 3.6e-21 75.7 6.8 1.2e-20 74.0 1.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4706) Phage_spike PF18715.1 PVD25410.1 - 0.18 11.9 1.7 0.38 10.9 1.7 1.5 1 0 0 1 1 1 0 Phage spike trimer IMS PF00817.20 PVD25411.1 - 5.5e-48 162.8 0.1 9.9e-48 161.9 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 PVD25411.1 - 1.9e-13 49.7 2.1 2.1e-13 49.6 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 PVD25411.1 - 1.1e-12 48.7 0.0 3.6e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PVD25411.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Actino_peptide PF14408.6 PVD25411.1 - 0.15 12.2 0.6 0.51 10.5 0.6 2.0 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes RasGEF PF00617.19 PVD25412.1 - 7.1e-47 159.9 0.6 1.4e-46 158.9 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain C1_1 PF00130.22 PVD25412.1 - 8.5e-13 48.0 9.3 8.5e-13 48.0 9.3 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.20 PVD25412.1 - 6.1e-12 45.7 0.0 1.8e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif EF-hand_5 PF13202.6 PVD25412.1 - 3.3e-08 32.6 0.3 0.00086 18.7 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 PVD25412.1 - 3.2e-07 29.4 5.3 0.00097 18.5 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD25412.1 - 9.4e-07 28.3 2.1 0.00093 18.9 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PVD25412.1 - 4.5e-06 27.0 0.1 0.036 14.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair Csm1_N PF18504.1 PVD25412.1 - 0.012 15.9 0.4 0.034 14.5 0.4 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain Caldesmon PF02029.15 PVD25412.1 - 0.046 12.5 3.3 0.068 11.9 3.3 1.1 1 0 0 1 1 1 0 Caldesmon RhoGAP PF00620.27 PVD25413.1 - 2.1e-34 118.6 1.5 4.5e-34 117.5 0.8 2.1 2 0 0 2 2 2 1 RhoGAP domain Lectin_C_term PF18022.1 PVD25413.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain Clat_adaptor_s PF01217.20 PVD25415.1 - 1.5e-61 206.5 7.1 1.6e-61 206.4 7.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M14 PF00246.24 PVD25416.1 - 2.9e-28 99.5 0.1 3.6e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase pP_pnuc_1 PF18165.1 PVD25417.1 - 0.011 15.7 0.7 0.013 15.4 0.7 1.1 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease CENP-F_leu_zip PF10473.9 PVD25417.1 - 0.033 14.2 7.7 0.039 14.0 7.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1902 PF08972.11 PVD25417.1 - 0.042 13.9 0.9 0.071 13.1 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1902) IL2 PF00715.17 PVD25417.1 - 0.077 12.9 3.2 0.12 12.3 3.2 1.5 1 1 0 1 1 1 0 Interleukin 2 TrmO_C PF18389.1 PVD25417.1 - 0.67 10.1 4.7 0.6 10.3 3.2 1.7 1 1 1 2 2 2 0 TrmO C-terminal domain DUF3450 PF11932.8 PVD25417.1 - 0.87 8.8 12.4 1.3 8.3 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DAO PF01266.24 PVD25419.1 - 6.3e-22 78.6 0.0 7.7e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PVD25419.1 - 0.089 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAS_11 PF14598.6 PVD25420.1 - 6e-21 74.7 0.0 6.7e-18 64.9 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 PVD25420.1 - 4.2e-20 71.8 0.0 8.3e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PVD25420.1 - 2.4e-08 34.2 0.0 0.016 15.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 PVD25420.1 - 5.5e-08 32.8 0.1 1e-05 25.5 0.1 3.2 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.7 PVD25420.1 - 4.1e-05 23.8 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 PVD25420.1 - 0.0025 17.7 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_2 PF08446.11 PVD25420.1 - 0.071 13.8 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold Paired_CXXCH_1 PF09699.10 PVD25420.1 - 0.081 12.7 0.4 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) RNase_P_Rpp14 PF01900.19 PVD25421.1 - 0.17 12.1 3.6 0.25 11.6 1.2 2.7 2 0 0 2 2 2 0 Rpp14/Pop5 family Kunitz_BPTI PF00014.23 PVD25422.1 - 6.2e-20 71.2 17.8 7e-11 42.2 3.9 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF4648 PF15505.6 PVD25422.1 - 0.04 14.8 0.1 0.14 13.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Peptidase_M49 PF03571.15 PVD25426.1 - 6.6e-233 774.1 0.0 7.7e-233 773.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF966 PF06136.13 PVD25428.1 - 0.026 14.2 27.9 0.039 13.7 27.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF936 PF06075.12 PVD25428.1 - 0.1 11.5 24.9 0.12 11.2 24.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CAC1F_C PF16885.5 PVD25428.1 - 0.63 9.7 22.8 0.78 9.3 22.8 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term LAP1C PF05609.12 PVD25428.1 - 1.4 8.0 34.7 1.6 7.7 34.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Caldesmon PF02029.15 PVD25428.1 - 2.1 7.0 37.0 2.8 6.6 37.0 1.1 1 0 0 1 1 1 0 Caldesmon GREB1 PF15782.5 PVD25428.1 - 2.2 5.3 31.0 2.5 5.1 31.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 PVD25428.1 - 2.9 7.8 42.5 4.1 7.3 42.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PVD25428.1 - 7.7 5.1 23.7 8.8 4.9 23.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWI-SNF_Ssr4 PF08549.10 PVD25428.1 - 7.8 5.0 31.4 8.6 4.9 31.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PRIMA1 PF16101.5 PVD25429.1 - 0.014 15.4 11.9 0.028 14.5 11.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD25429.1 - 0.11 12.0 8.3 0.14 11.6 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD25429.1 - 0.12 12.4 4.6 0.18 11.8 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Glyco_hydro_38N PF01074.22 PVD25431.1 - 4.7e-87 292.0 6.2 8.2e-87 291.2 6.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PVD25431.1 - 3.6e-18 66.4 0.0 7.5e-12 45.8 0.0 3.0 2 1 1 3 3 3 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PVD25431.1 - 4.4e-16 58.8 1.0 9e-16 57.8 1.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain AAA_33 PF13671.6 PVD25432.1 - 9.2e-31 106.9 0.0 2.2e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 PVD25432.1 - 5.1e-14 51.6 1.6 1e-13 50.7 1.6 1.5 1 0 0 1 1 1 1 SAP domain SPRY PF00622.28 PVD25432.1 - 1.1e-10 41.7 0.0 3.2e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 SPRY domain Zeta_toxin PF06414.12 PVD25432.1 - 0.0002 20.7 0.2 0.00053 19.3 0.2 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 PVD25432.1 - 0.00095 19.7 0.1 0.0043 17.6 0.1 2.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 PVD25432.1 - 0.042 13.3 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 EF-hand_7 PF13499.6 PVD25433.1 - 8.3e-14 51.8 0.0 8.4e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD25433.1 - 5e-10 38.5 0.1 0.0023 17.7 0.0 4.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 PVD25433.1 - 1.5e-07 30.4 1.2 0.018 14.5 0.0 4.5 6 0 0 6 6 6 2 EF hand EF-hand_9 PF14658.6 PVD25433.1 - 2.8e-06 27.5 0.1 0.012 15.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD25433.1 - 4.1e-06 26.5 0.0 0.0065 16.3 0.0 3.1 3 1 1 4 4 4 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 PVD25433.1 - 0.0013 18.7 0.2 0.0033 17.5 0.2 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Dpoe2NT PF12213.8 PVD25433.1 - 0.029 14.7 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal CAAP1 PF15335.6 PVD25433.1 - 0.075 13.6 0.0 0.16 12.5 0.0 1.5 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Mcl1_mid PF12341.8 PVD25434.1 - 3e-99 332.1 0.0 5.6e-99 331.2 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 PVD25434.1 - 1.6e-11 44.6 15.0 0.00019 22.1 0.7 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25434.1 - 1.7e-07 31.4 3.2 0.00045 20.5 0.2 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 PVD25434.1 - 3.7e-06 27.3 0.1 1.3e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD25434.1 - 0.011 16.3 0.3 0.028 15.0 0.3 1.7 1 0 0 1 1 1 0 HMG-box domain Translin PF01997.16 PVD25436.1 - 2e-23 83.5 0.0 2.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Translin family Pur_ac_phosph_N PF16656.5 PVD25437.1 - 2.3e-20 73.0 0.1 3e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PVD25438.1 - 4.5e-18 65.9 0.0 9.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 PVD25438.1 - 2.3e-10 41.3 0.1 8.5e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PVD25439.1 - 4e-41 139.7 8.0 3.6e-20 72.6 0.3 3.5 3 0 0 3 3 3 2 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PVD25439.1 - 1.5e-31 108.9 7.6 5.3e-15 55.8 0.3 3.8 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 PVD25439.1 - 4.9e-25 89.2 20.6 1e-15 58.8 6.5 3.7 2 2 0 2 2 2 2 Calcineurin-like phosphoesterase fn3 PF00041.21 PVD25439.1 - 0.0011 19.3 7.0 0.075 13.4 0.2 3.5 4 0 0 4 4 4 2 Fibronectin type III domain PhoD PF09423.10 PVD25439.1 - 0.057 12.4 5.7 1.2 8.1 0.4 2.5 3 0 0 3 3 3 0 PhoD-like phosphatase Metallophos_C PF14008.6 PVD25440.1 - 9.1e-19 68.1 0.0 2.9e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 PVD25440.1 - 1.9e-15 57.9 0.4 1.9e-15 57.9 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PVD25440.1 - 3.3e-10 40.4 0.0 3.3e-10 40.4 0.0 2.8 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Hormone_2 PF00123.20 PVD25441.1 - 0.015 15.2 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 Peptide hormone Glyco_hydro_42 PF02449.15 PVD25444.1 - 0.065 12.6 0.4 0.31 10.3 0.2 2.0 1 1 1 2 2 2 0 Beta-galactosidase bZIP_1 PF00170.21 PVD25445.1 - 7e-08 32.5 11.6 1.5e-07 31.4 11.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor APC_N_CC PF16689.5 PVD25445.1 - 0.013 15.5 4.1 0.027 14.5 4.1 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF572 PF04502.13 PVD25445.1 - 0.027 14.1 4.0 0.036 13.7 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) bZIP_2 PF07716.15 PVD25445.1 - 0.044 13.9 17.3 0.074 13.1 12.2 3.2 2 1 1 3 3 3 0 Basic region leucine zipper bZIP_Maf PF03131.17 PVD25445.1 - 0.17 12.4 5.6 0.43 11.1 5.6 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.11 PVD25445.1 - 0.17 12.0 4.7 0.26 11.4 4.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 PVD25445.1 - 0.19 10.6 1.8 0.22 10.4 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 PVD25445.1 - 0.26 11.1 6.0 0.44 10.3 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 PVD25445.1 - 0.3 11.4 7.2 1.5 9.1 2.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 PVD25445.1 - 0.39 11.0 6.5 0.78 10.0 6.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 PVD25445.1 - 1.9 9.1 6.9 3 8.5 5.3 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Ank_2 PF12796.7 PVD25446.1 - 1.7e-33 115.0 0.8 1.7e-08 34.9 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25446.1 - 3.5e-27 94.4 2.7 1.6e-07 31.7 0.0 6.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25446.1 - 4.3e-27 91.2 1.2 0.0024 18.2 0.0 8.4 7 1 1 8 8 8 4 Ankyrin repeat Ank PF00023.30 PVD25446.1 - 7.1e-26 89.5 0.5 2.7e-05 24.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 PVD25446.1 - 3.3e-18 65.5 1.1 0.013 15.8 0.0 6.2 6 1 0 6 6 6 4 Ankyrin repeats (many copies) HTH_16 PF12645.7 PVD25446.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Kelch_1 PF01344.25 PVD25447.1 - 3.5e-62 205.8 10.3 1.5e-14 53.3 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD25447.1 - 1.2e-30 104.7 3.8 1.9e-09 37.4 0.0 6.4 3 1 4 7 7 7 5 Kelch motif Kelch_2 PF07646.15 PVD25447.1 - 8.6e-26 88.9 1.0 1.2e-05 25.1 0.0 6.2 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 PVD25447.1 - 5.8e-20 71.3 0.1 1.6e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD25447.1 - 5e-18 64.9 1.5 5.7e-05 23.0 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD25447.1 - 4.6e-12 45.9 5.0 0.059 13.7 0.0 5.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD25447.1 - 6.8e-11 41.9 12.3 0.011 15.7 0.2 5.8 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 PVD25447.1 - 2.9e-05 24.2 0.4 0.00017 21.8 0.1 2.3 2 1 1 3 3 3 1 BTB/POZ domain DUF5122 PF17164.4 PVD25447.1 - 0.078 13.3 3.1 28 5.1 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller EMP24_GP25L PF01105.24 PVD25448.1 - 1.6e-34 119.4 0.2 2.6e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bile_Hydr_Trans PF04775.14 PVD25448.1 - 2.2e-29 102.0 0.0 5.8e-29 100.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 PVD25448.1 - 2.2e-23 83.3 0.0 8.3e-23 81.4 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal SMC_N PF02463.19 PVD25448.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain BAAT_C PF08840.11 PVD25449.1 - 1.1e-29 103.9 0.0 1.8e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 PVD25449.1 - 1.8e-07 31.3 0.0 3.8e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 PVD25449.1 - 0.0022 17.6 0.1 0.02 14.4 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PVD25449.1 - 0.0036 16.8 0.1 0.071 12.6 0.1 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 PVD25449.1 - 0.036 13.5 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase RAP PF08373.10 PVD25449.1 - 0.057 13.5 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 RAP domain AXE1 PF05448.12 PVD25449.1 - 0.079 11.6 0.0 0.63 8.7 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) C1_2 PF03107.16 PVD25449.1 - 0.09 13.1 1.5 0.21 11.9 1.5 1.5 1 0 0 1 1 1 0 C1 domain Ank_4 PF13637.6 PVD25450.1 - 3.4e-13 49.8 0.0 3.8e-05 24.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD25450.1 - 2e-12 47.5 0.3 7e-11 42.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) CHB_HEX_C_1 PF13290.6 PVD25450.1 - 1e-10 41.4 0.1 2.6e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_5 PF13857.6 PVD25450.1 - 1.9e-09 37.6 0.1 2.7e-05 24.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Fn3_assoc PF13287.6 PVD25450.1 - 8.1e-09 35.5 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Fn3 associated Ank_3 PF13606.6 PVD25450.1 - 2.5e-08 33.5 0.0 0.11 13.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PVD25450.1 - 1.3e-07 31.7 0.5 0.085 13.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat RVP PF00077.20 PVD25450.1 - 0.036 14.4 0.1 0.41 11.0 0.0 2.6 1 1 1 2 2 2 0 Retroviral aspartyl protease TPR_2 PF07719.17 PVD25451.1 - 3.9e-15 54.6 1.5 0.00021 21.2 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD25451.1 - 9.8e-15 53.7 0.6 3.6e-05 23.4 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD25451.1 - 6.5e-12 44.7 0.1 0.0029 17.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD25451.1 - 1.4e-09 37.5 0.2 5.7e-05 22.7 0.1 3.7 2 1 2 4 4 4 2 TPR repeat TPR_7 PF13176.6 PVD25451.1 - 3.4e-09 36.1 6.2 0.047 13.7 0.0 5.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD25451.1 - 3.6e-07 30.4 4.4 0.00058 20.1 0.1 5.3 1 1 3 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD25451.1 - 4.8e-06 26.7 1.3 0.00021 21.4 0.3 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD25451.1 - 1.2e-05 25.7 2.6 1.2 10.2 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD25451.1 - 4.3e-05 23.6 1.3 0.17 12.0 0.0 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD25451.1 - 0.0003 21.4 1.6 0.12 13.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD25451.1 - 0.00052 19.8 4.2 0.14 12.1 0.0 4.9 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD25451.1 - 0.0009 19.5 0.6 0.19 12.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 PVD25451.1 - 0.00095 18.6 0.1 0.85 9.1 0.0 2.9 3 0 0 3 3 3 2 SHNi-TPR TPR_19 PF14559.6 PVD25451.1 - 0.0015 19.0 1.2 1.2 9.7 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD25451.1 - 0.42 11.4 4.4 41 5.1 0.0 4.7 5 2 1 6 6 4 0 Tetratricopeptide repeat FSIP1 PF15554.6 PVD25452.1 - 1.9e-62 211.7 26.0 3.5e-62 210.8 26.0 1.4 1 0 0 1 1 1 1 FSIP1 family SR-25 PF10500.9 PVD25452.1 - 0.012 15.2 3.6 0.012 15.2 3.6 3.0 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein AIF_C PF14721.6 PVD25452.1 - 0.96 9.8 3.2 3.8 7.9 3.2 2.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Secretin_N_2 PF07655.13 PVD25452.1 - 1.1 9.9 10.3 5.1 7.7 3.7 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain RNA_pol_Rpc4 PF05132.14 PVD25452.1 - 1.5 9.2 5.3 4.5 7.7 5.3 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 Fibrinogen_C PF00147.18 PVD25453.1 - 8.9e-45 153.2 12.5 1.1e-44 152.9 12.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Atu4866 PF11512.8 PVD25453.1 - 0.037 14.4 2.7 11 6.5 0.1 3.4 2 1 1 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 EF-hand_7 PF13499.6 PVD25454.1 - 1e-07 32.3 0.1 4.2e-07 30.3 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD25454.1 - 9e-07 28.3 0.0 0.00081 19.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD25454.1 - 2.6e-06 26.6 0.1 0.077 12.6 0.0 2.6 2 0 0 2 2 2 2 EF hand Glu-tRNAGln PF02686.15 PVD25454.1 - 0.016 15.5 0.3 0.032 14.5 0.3 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Nup54_C PF18437.1 PVD25454.1 - 0.03 14.2 1.7 0.37 10.7 0.9 2.8 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain EF-hand_8 PF13833.6 PVD25454.1 - 0.033 14.0 0.2 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD25454.1 - 0.039 14.3 0.5 0.65 10.3 0.1 2.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD25454.1 - 0.059 13.3 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Homeodomain PF00046.29 PVD25455.1 - 3.4e-13 49.2 0.9 6e-13 48.4 0.9 1.4 1 0 0 1 1 1 1 Homeodomain NAD_binding_1 PF00175.21 PVD25455.1 - 0.12 13.0 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Homeodomain PF00046.29 PVD25457.1 - 0.0012 18.6 2.3 0.0022 17.8 2.3 1.4 1 0 0 1 1 1 1 Homeodomain EF-hand_7 PF13499.6 PVD25458.1 - 8.5e-09 35.7 6.1 1.1e-08 35.4 5.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD25458.1 - 3.2e-08 32.9 2.4 0.00013 21.7 0.7 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD25458.1 - 9.6e-06 24.8 0.6 0.05 13.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD25458.1 - 0.015 15.2 1.3 0.25 11.2 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair Gluconate_2-dh3 PF13618.6 PVD25458.1 - 0.052 13.8 0.0 5.3 7.3 0.1 2.1 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 EF-hand_5 PF13202.6 PVD25458.1 - 0.071 12.6 0.4 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 EF hand DivIC PF04977.15 PVD25459.1 - 0.0091 15.7 0.3 0.0091 15.7 0.3 12.7 5 4 8 13 13 13 3 Septum formation initiator FlaC_arch PF05377.11 PVD25459.1 - 0.1 13.0 0.3 0.1 13.0 0.3 9.1 8 1 1 9 9 9 0 Flagella accessory protein C (FlaC) Receptor_IA-2 PF11548.8 PVD25459.1 - 1.6 8.8 9.5 0.044 13.8 1.0 2.9 3 0 0 3 3 3 0 Protein-tyrosine phosphatase receptor IA-2 Gal-bind_lectin PF00337.22 PVD25460.1 - 1e-146 481.5 12.4 1.1e-39 135.0 0.1 4.2 4 0 0 4 4 4 4 Galactoside-binding lectin Alginate_lyase2 PF08787.11 PVD25460.1 - 0.0047 16.8 0.1 6.3 6.6 0.0 3.2 3 0 0 3 3 3 2 Alginate lyase DUF1583 PF07622.11 PVD25460.1 - 0.027 13.2 0.8 0.61 8.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1583) PDDEXK_5 PF11645.8 PVD25460.1 - 0.071 13.1 0.1 3.5 7.6 0.0 3.0 4 0 0 4 4 4 0 PD-(D/E)XK endonuclease zf-CCHH PF10283.9 PVD25460.1 - 0.087 12.8 12.5 0.42 10.6 1.1 4.4 4 0 0 4 4 4 0 PBZ domain SRP40_C PF05022.12 PVD25460.1 - 0.16 12.8 0.0 26 5.7 0.0 2.5 2 0 0 2 2 2 0 SRP40, C-terminal domain DNA_pol3_beta PF00712.19 PVD25460.1 - 0.21 11.8 0.1 8 6.6 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain Glyco_hydro_31 PF01055.26 PVD25461.1 - 9.2e-145 483.2 3.9 1.5e-144 482.5 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 PVD25461.1 - 9.7e-24 83.5 0.1 1.5e-22 79.6 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 PVD25461.1 - 0.001 19.3 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF1581 PF07619.11 PVD25461.1 - 0.016 15.4 0.0 0.49 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Med12-LCEWAV PF12145.8 PVD25461.1 - 0.16 10.8 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DUF1682 PF07946.14 PVD25461.1 - 0.91 8.7 6.6 1.7 7.8 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAM176 PF14851.6 PVD25461.1 - 3 7.5 5.1 5.6 6.6 5.1 1.3 1 0 0 1 1 1 0 FAM176 family RhoGEF PF00621.20 PVD25462.1 - 9.6e-41 140.0 0.0 1.4e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PVD25462.1 - 6.2e-06 26.7 0.0 2.2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 PH domain Hrs_helical PF12210.8 PVD25462.1 - 0.066 13.8 1.5 0.18 12.4 1.5 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate dCMP_cyt_deam_1 PF00383.23 PVD25463.1 - 3.6e-11 42.8 0.1 8.3e-11 41.7 0.1 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PVD25463.1 - 7.4e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Secretin_N PF03958.17 PVD25463.1 - 0.049 14.0 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Bd3614-deam PF14439.6 PVD25463.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase MFS_1 PF07690.16 PVD25464.1 - 2.5e-25 89.2 24.6 2.5e-25 89.2 24.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2678 PF10856.8 PVD25464.1 - 0.081 12.9 6.3 1.4 8.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) CLP_protease PF00574.23 PVD25464.1 - 0.12 12.2 2.0 0.25 11.2 2.0 1.4 1 0 0 1 1 1 0 Clp protease RRP36 PF06102.12 PVD25465.1 - 1.8e-46 158.1 34.1 1.8e-46 158.1 34.1 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ANAPC2 PF08672.11 PVD25465.1 - 1.6 9.3 5.7 5.4 7.6 2.6 2.8 2 1 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Ureide_permease PF07168.11 PVD25465.1 - 4.1 6.1 8.1 6.4 5.4 8.1 1.3 1 0 0 1 1 1 0 Ureide permease FHA PF00498.26 PVD25467.1 - 2.7e-08 34.1 0.1 7.8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain PRIMA1 PF16101.5 PVD25467.1 - 0.053 13.6 8.9 1.2 9.2 0.6 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Yop-YscD_cpl PF16697.5 PVD25467.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain NPR1_interact PF15699.5 PVD25468.1 - 0.38 11.4 6.0 0.18 12.4 2.0 2.6 2 0 0 2 2 2 0 NPR1 interacting Macro PF01661.21 PVD25469.1 - 7.5e-40 135.7 0.6 1.4e-39 134.8 0.6 1.5 1 0 0 1 1 1 1 Macro domain DUF637 PF04830.13 PVD25469.1 - 0.0032 17.3 0.2 0.0062 16.4 0.2 1.4 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) Pkinase PF00069.25 PVD25470.1 - 1.3e-67 228.0 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25470.1 - 8.3e-44 149.8 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 PVD25470.1 - 9.4e-13 48.3 0.1 3e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 PVD25470.1 - 1.5e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PVD25470.1 - 1.6 8.3 4.6 0.46 10.1 0.2 2.2 2 0 0 2 2 2 0 RIO1 family EGF PF00008.27 PVD25471.1 - 2.2e-17 63.0 45.9 3.3e-07 30.5 8.3 4.0 4 0 0 4 4 4 3 EGF-like domain EGF_2 PF07974.13 PVD25471.1 - 2e-06 28.1 53.0 0.0086 16.4 11.7 3.9 4 1 0 4 4 4 3 EGF-like domain hEGF PF12661.7 PVD25471.1 - 0.00013 22.5 44.3 0.00027 21.4 7.4 4.9 4 1 0 4 4 4 3 Human growth factor-like EGF EGF_Tenascin PF18720.1 PVD25471.1 - 0.054 13.6 3.1 0.054 13.6 3.1 5.4 5 1 0 5 5 5 0 Tenascin EGF domain Laminin_EGF PF00053.24 PVD25471.1 - 4.1 7.6 37.2 4.7 7.4 5.6 4.4 2 1 2 4 4 4 0 Laminin EGF domain Bile_Hydr_Trans PF04775.14 PVD25472.1 - 1.1e-27 96.6 0.0 1.9e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 PVD25472.1 - 6.7e-26 91.5 0.0 1.3e-18 67.8 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Cyclase PF04199.13 PVD25473.1 - 2.2e-37 128.3 0.0 3.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase GFRP PF06399.13 PVD25473.1 - 3.3e-33 113.4 0.0 7.4e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) Beach PF02138.18 PVD25475.1 - 1.1e-42 146.4 0.3 2.8e-42 145.0 0.3 1.7 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 PVD25475.1 - 3.8e-11 43.4 7.8 0.0075 17.1 0.1 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25475.1 - 0.063 13.6 0.0 0.5 10.7 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 PVD25476.1 - 2.5e-17 62.6 0.4 4.7e-17 61.7 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ATG16 PF08614.11 PVD25476.1 - 0.019 15.2 2.6 0.039 14.2 2.6 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 PVD25476.1 - 0.03 14.9 3.1 0.031 14.9 1.9 1.7 2 0 0 2 2 2 0 SlyX CREPT PF16566.5 PVD25476.1 - 0.043 14.0 2.9 0.059 13.5 2.9 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PMBR PF09373.10 PVD25476.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat COE1_HLH PF16423.5 PVD25476.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain MPM1 PF17234.2 PVD25476.1 - 0.73 10.1 5.8 0.92 9.7 5.8 1.3 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Dehydrin PF00257.19 PVD25476.1 - 2.3 8.7 9.2 3.2 8.3 8.7 1.5 1 1 0 1 1 1 0 Dehydrin bZIP_2 PF07716.15 PVD25476.1 - 5.6 7.1 10.9 0.12 12.4 3.2 2.2 3 0 0 3 3 3 0 Basic region leucine zipper Dicer_dimer PF03368.14 PVD25477.1 - 0.0041 17.2 0.1 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain TSC22 PF01166.18 PVD25477.1 - 0.69 10.3 4.4 2.8 8.3 4.4 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Transglut_core PF01841.19 PVD25478.1 - 3.2e-05 24.3 0.0 0.00013 22.4 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF1484 PF07363.11 PVD25480.1 - 0.57 11.2 4.0 17 6.5 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1484) C2 PF00168.30 PVD25481.1 - 1.8e-27 95.6 0.0 2.1e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain BBS1 PF14779.6 PVD25482.1 - 2e-110 368.2 0.1 2.5e-109 364.6 0.0 2.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 PVD25482.1 - 1.1e-06 28.6 0.0 0.15 12.1 0.0 3.7 2 1 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 PVD25482.1 - 0.0015 18.0 0.0 0.0071 15.7 0.0 1.8 1 1 1 2 2 2 1 PTHB1 N-terminus PQQ_3 PF13570.6 PVD25482.1 - 0.0046 17.4 0.0 15 6.2 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain TcfC PF16967.5 PVD25482.1 - 0.023 14.2 0.1 0.59 9.7 0.0 2.9 3 0 0 3 3 3 0 E-set like domain ANAPC4_WD40 PF12894.7 PVD25482.1 - 0.081 13.2 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain ERCC4 PF02732.15 PVD25483.1 - 1.9e-17 63.9 0.1 4.1e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 ERCC4 domain Prenyltrans PF00432.21 PVD25484.1 - 7.6e-46 153.5 9.4 1.1e-11 44.3 0.6 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat BLM10_mid PF16507.5 PVD25485.1 - 1.8e-92 310.7 0.2 9.5e-91 305.0 0.1 2.8 2 1 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 PVD25485.1 - 4.5e-31 106.6 0.0 4.1e-30 103.5 0.0 2.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 PVD25485.1 - 4.6e-05 23.3 0.5 0.022 15.0 0.1 4.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 PVD25485.1 - 0.17 12.4 0.5 92 3.7 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat DHC_N1 PF08385.12 PVD25486.1 - 1.9e-117 393.3 20.0 4.5e-102 342.5 7.7 4.1 3 1 1 4 4 4 3 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PVD25486.1 - 1e-23 84.1 6.6 1e-23 84.1 6.6 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N2 PF08393.13 PVD25487.1 - 9.1e-77 258.8 1.3 5.9e-39 134.3 0.3 2.8 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PVD25487.1 - 1.2e-55 188.8 0.0 2e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 PVD25487.1 - 2.4e-06 28.0 0.2 1.3e-05 25.7 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PVD25487.1 - 0.00013 22.4 0.0 0.00048 20.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD25487.1 - 0.0019 18.5 0.6 0.013 15.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD25487.1 - 0.016 14.9 0.2 0.053 13.2 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PVD25487.1 - 0.022 14.5 0.3 0.12 12.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD25487.1 - 0.04 14.5 0.1 0.4 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 PVD25487.1 - 0.062 13.3 0.2 3.1 7.8 0.2 3.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PSK_trans_fac PF07704.11 PVD25487.1 - 0.1 13.4 2.1 3.2 8.6 0.0 3.5 3 0 0 3 3 3 0 Rv0623-like transcription factor RNA_helicase PF00910.22 PVD25487.1 - 0.13 12.6 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ALIX_LYPXL_bnd PF13949.6 PVD25487.1 - 0.31 10.3 5.9 0.11 11.8 0.3 2.7 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV AAA_23 PF13476.6 PVD25487.1 - 0.87 10.0 3.3 2.9 8.3 0.0 3.0 3 1 1 4 4 4 0 AAA domain AAA_9 PF12781.7 PVD25488.1 - 4.1e-72 241.9 0.0 4.1e-72 241.9 0.0 3.8 4 1 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 PVD25488.1 - 3.4e-69 233.1 0.0 1.7e-68 230.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 PVD25488.1 - 1e-65 221.9 0.0 5.2e-65 219.6 0.0 2.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 PVD25488.1 - 1.5e-43 148.4 0.0 2.9e-38 131.2 0.0 4.1 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 PVD25488.1 - 3.1e-41 141.5 14.0 5.2e-41 140.8 14.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PVD25488.1 - 9.1e-41 139.4 0.0 2.4e-40 138.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 PVD25488.1 - 7.5e-40 137.0 0.1 7.5e-40 137.0 0.1 2.0 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 PVD25488.1 - 1.3e-28 99.7 0.0 1.1e-12 48.1 0.0 4.6 4 0 0 4 4 3 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 PVD25488.1 - 2.7e-27 95.2 0.0 1e-25 90.1 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD25488.1 - 1.5e-19 70.3 0.0 9e-19 67.8 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 PVD25488.1 - 8.9e-14 51.9 0.5 0.0031 17.8 0.0 5.2 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.6 PVD25488.1 - 2.2e-12 47.3 0.6 0.00062 19.9 0.0 4.8 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 PVD25488.1 - 6.9e-11 42.7 0.0 0.0058 17.0 0.0 4.5 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PVD25488.1 - 2.1e-09 38.0 3.6 0.11 13.1 0.0 5.5 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 PVD25488.1 - 3.4e-09 37.3 0.1 0.29 11.5 0.0 5.4 5 0 0 5 5 4 2 AAA ATPase domain Mg_chelatase PF01078.21 PVD25488.1 - 1e-07 31.5 0.1 0.34 10.3 0.0 4.3 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 PVD25488.1 - 1.2e-07 31.1 0.0 0.019 14.0 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.6 PVD25488.1 - 3.3e-06 26.7 0.1 0.51 10.1 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.6 PVD25488.1 - 4.6e-06 26.7 0.0 1.3 9.0 0.0 4.5 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 PVD25488.1 - 3.1e-05 24.5 5.5 0.3 11.6 0.0 4.9 5 1 0 5 5 4 2 ABC transporter Rad17 PF03215.15 PVD25488.1 - 3.8e-05 23.7 0.0 0.91 9.4 0.0 4.0 3 0 0 3 3 3 1 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 PVD25488.1 - 8.7e-05 22.0 0.0 0.43 9.9 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 PVD25488.1 - 0.00012 22.3 0.0 0.00084 19.5 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain AAA_19 PF13245.6 PVD25488.1 - 0.00014 22.2 0.1 0.18 12.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PVD25488.1 - 0.00017 21.4 0.0 2.6 7.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PVD25488.1 - 0.00019 21.2 0.7 0.1 12.3 0.0 3.9 4 1 0 4 4 3 1 IstB-like ATP binding protein EF-hand_13 PF17958.1 PVD25488.1 - 0.00048 19.9 0.0 0.0015 18.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 PVD25488.1 - 0.001 19.5 8.2 0.028 14.9 0.0 5.3 3 1 2 5 5 4 2 EF-hand domain pair RNA_helicase PF00910.22 PVD25488.1 - 0.0021 18.4 0.1 3.9 7.9 0.0 4.4 5 0 0 5 5 3 1 RNA helicase AAA_25 PF13481.6 PVD25488.1 - 0.0041 16.7 0.1 0.19 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 PVD25488.1 - 0.011 15.4 0.2 18 5.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 PVD25488.1 - 0.013 15.4 0.1 7.9 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 PVD25488.1 - 0.014 15.3 0.1 0.46 10.3 0.1 3.2 3 0 0 3 3 3 0 Deoxynucleoside kinase NACHT PF05729.12 PVD25488.1 - 0.016 15.1 0.2 33 4.3 0.0 4.1 3 0 0 3 3 3 0 NACHT domain EF-hand_6 PF13405.6 PVD25488.1 - 0.025 14.5 1.3 11 6.3 0.0 3.9 4 0 0 4 4 2 0 EF-hand domain RuvB_N PF05496.12 PVD25488.1 - 0.04 13.7 0.1 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 PVD25488.1 - 0.071 13.1 0.0 23 5.0 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PVD25488.1 - 1.8 9.0 26.5 3.8 7.9 1.0 5.6 6 0 0 6 6 5 0 AAA domain DUF4710 PF15828.5 PVD25489.1 - 0.75 9.9 5.3 1.9 8.6 3.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4710) Pkinase PF00069.25 PVD25490.1 - 9.5e-75 251.4 0.0 1.5e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25490.1 - 5.8e-36 124.1 0.0 9.4e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 PVD25490.1 - 1.4e-15 57.4 8.2 9.7e-06 26.2 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Kinase-like PF14531.6 PVD25490.1 - 5.5e-07 29.2 0.0 9.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ANAPC4_WD40 PF12894.7 PVD25490.1 - 0.0035 17.6 0.1 22 5.5 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Atg8 PF02991.16 PVD25491.1 - 1.1e-39 134.8 0.4 1.3e-39 134.6 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 PVD25491.1 - 4.3e-05 23.9 0.1 6e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TALPID3 PF15324.6 PVD25492.1 - 1.6e-61 208.4 65.2 3e-55 187.6 65.2 2.2 1 1 0 1 1 1 1 Hedgehog signalling target IRF-2BP1_2 PF11261.8 PVD25495.1 - 5e-33 112.4 1.1 5e-33 112.4 1.1 1.7 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 PVD25495.1 - 0.0039 17.0 6.1 0.0094 15.8 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD25495.1 - 0.068 13.0 7.3 0.25 11.2 7.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TALPID3 PF15324.6 PVD25496.1 - 3.8e-27 94.5 10.7 3.8e-27 94.5 10.7 1.5 2 0 0 2 2 2 1 Hedgehog signalling target OmpH PF03938.14 PVD25496.1 - 5.4 7.4 14.7 0.51 10.7 8.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-Tim10_DDP PF02953.15 PVD25497.1 - 5.2e-16 58.0 3.3 8.3e-16 57.4 3.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tyr-DNA_phospho PF06087.12 PVD25498.1 - 8.5e-126 420.3 0.0 1.1e-125 419.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 PVD25498.1 - 5e-10 39.2 4.9 1.3e-09 37.8 4.9 1.7 1 0 0 1 1 1 1 PBZ domain zf-CCCH_4 PF18044.1 PVD25498.1 - 0.097 12.5 1.7 0.25 11.2 1.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Tnp_22_trimer PF17489.2 PVD25498.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain PAX PF00292.18 PVD25499.1 - 6.5e-67 223.2 0.3 8.8e-67 222.7 0.3 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 PVD25499.1 - 5e-07 29.3 0.0 1.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 PVD25499.1 - 1.6e-05 25.4 1.4 0.00048 20.7 0.0 2.7 2 1 1 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 PVD25499.1 - 0.0025 17.9 0.0 0.0099 16.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 PVD25499.1 - 0.0029 17.6 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 PVD25499.1 - 0.67 9.8 2.8 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Metallophos_C PF14008.6 PVD25501.1 - 6.2e-19 68.6 1.0 1.6e-18 67.3 0.0 2.3 2 1 1 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 PVD25501.1 - 2.4e-18 67.4 0.2 3.7e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lamp PF01299.17 PVD25502.1 - 3.9e-10 39.8 0.2 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 PVD25502.1 - 0.00022 21.0 0.1 0.0007 19.4 0.0 1.8 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Utp12 PF04003.12 PVD25504.1 - 2.4e-19 69.6 1.1 5.1e-19 68.6 1.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 PVD25504.1 - 2.9e-09 37.1 0.1 0.0031 17.8 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD25504.1 - 2.9e-07 31.0 13.6 0.0095 16.8 0.0 5.8 5 2 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 PVD25504.1 - 0.24 10.7 0.0 0.47 9.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Nucleoside_tran PF01733.18 PVD25505.1 - 1.2e-54 185.8 2.4 1.2e-54 185.8 2.4 2.6 1 1 0 2 2 2 1 Nucleoside transporter DUF4515 PF14988.6 PVD25506.1 - 3e-07 30.5 9.0 3e-07 30.5 9.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) PhyH PF05721.13 PVD25506.1 - 0.42 10.8 2.3 0.89 9.8 2.3 1.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Cupin_4 PF08007.12 PVD25506.1 - 6.9 6.0 11.7 2.3 7.6 5.6 2.3 1 1 1 2 2 2 0 Cupin superfamily protein Seadorna_VP6 PF07407.11 PVD25507.1 - 0.077 11.9 0.8 0.091 11.7 0.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein VCX_VCY PF15231.6 PVD25507.1 - 0.1 13.2 3.9 0.12 13.1 3.9 1.2 1 0 0 1 1 1 0 Variable charge X/Y family GDA1_CD39 PF01150.17 PVD25508.1 - 2.1e-55 188.1 0.1 5.7e-53 180.1 0.0 3.0 2 1 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 PVD25508.1 - 0.054 12.9 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Orn_Arg_deC_N PF02784.16 PVD25509.1 - 1.3e-43 149.2 0.0 1.3e-40 139.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Cofilin_ADF PF00241.20 PVD25509.1 - 7.4e-28 96.8 0.0 1.3e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Orn_DAP_Arg_deC PF00278.22 PVD25509.1 - 2.3e-09 37.4 0.0 8.3e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 PVD25509.1 - 1.3e-06 28.2 0.0 3.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain RyR PF02026.16 PVD25510.1 - 9e-121 394.4 3.0 1.9e-30 104.9 0.2 5.0 4 0 0 4 4 4 4 RyR domain RYDR_ITPR PF01365.21 PVD25510.1 - 2.5e-117 389.5 2.5 5.4e-61 205.6 0.3 3.1 2 0 0 2 2 2 2 RIH domain SPRY PF00622.28 PVD25510.1 - 1.4e-62 209.1 2.3 1.7e-22 79.8 0.0 3.6 3 0 0 3 3 3 3 SPRY domain MIR PF02815.19 PVD25510.1 - 2.7e-48 164.3 0.0 9.2e-47 159.3 0.0 2.5 2 0 0 2 2 2 1 MIR domain RR_TM4-6 PF06459.12 PVD25510.1 - 4.3e-41 141.6 0.1 4.3e-41 141.6 0.1 2.3 2 0 0 2 2 1 1 Ryanodine Receptor TM 4-6 Ins145_P3_rec PF08709.11 PVD25510.1 - 5.1e-38 130.4 0.9 1.5e-24 86.4 0.1 3.1 2 1 1 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 PVD25510.1 - 4.5e-32 109.9 1.0 1.4e-29 101.9 0.2 4.1 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ion_trans PF00520.31 PVD25510.1 - 3.9e-13 49.2 7.2 3.9e-13 49.2 7.2 2.2 2 0 0 2 2 1 1 Ion transport protein EF-hand_7 PF13499.6 PVD25510.1 - 3.1e-11 43.6 1.3 1.1e-10 41.7 1.3 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD25510.1 - 2.1e-09 36.3 1.4 0.0023 17.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD25510.1 - 1.7e-08 34.2 2.6 5.3e-08 32.6 0.8 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD25510.1 - 1e-07 31.1 0.1 0.01 15.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD25510.1 - 2e-06 27.2 0.5 0.0013 18.5 0.0 3.2 2 0 0 2 2 2 1 EF-hand domain ADP_ribosyl_GH PF03747.14 PVD25510.1 - 0.013 15.2 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase SPARC_Ca_bdg PF10591.9 PVD25510.1 - 0.16 12.3 2.2 0.26 11.6 0.6 2.2 2 0 0 2 2 1 0 Secreted protein acidic and rich in cysteine Ca binding region Bile_Hydr_Trans PF04775.14 PVD25511.1 - 2.3e-27 95.5 0.0 3.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 PVD25511.1 - 3e-08 33.8 0.0 7e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal XPG_N PF00752.17 PVD25512.1 - 1.2e-21 77.0 0.0 3.1e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 PVD25512.1 - 1.3e-18 67.2 0.0 4.7e-18 65.3 0.0 2.1 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 PVD25512.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing DUF4509 PF14970.6 PVD25514.1 - 1.9e-31 109.4 0.3 1.9e-31 109.4 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4509) ClpS PF02617.17 PVD25514.1 - 4e-22 77.8 1.0 1.3e-21 76.1 0.2 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 PVD25514.1 - 8.3e-22 77.1 10.8 8.3e-22 77.1 10.8 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) DUF4280 PF14107.6 PVD25515.1 - 0.0013 19.5 0.3 1.1 10.2 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4280) zf-C3HC4_2 PF13923.6 PVD25515.1 - 0.033 14.0 0.5 0.033 14.0 0.5 3.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Xol-1_GHMP-like PF09109.10 PVD25517.1 - 0.0091 15.9 1.0 0.014 15.2 1.0 1.3 1 1 0 1 1 1 1 Switch protein XOL-1, GHMP-like Arteri_nsp7a PF16749.5 PVD25517.1 - 0.033 14.4 0.2 0.092 12.9 0.2 1.8 1 1 1 2 2 2 0 Arterivirus nonstructural protein 7 alpha DUF5070 PF16802.5 PVD25517.1 - 0.16 11.9 0.6 0.28 11.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) RhoGEF PF00621.20 PVD25518.1 - 1.6e-29 103.5 0.4 3.6e-29 102.3 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain DASH_Dam1 PF08653.10 PVD25518.1 - 0.037 13.8 0.6 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 XhlA PF10779.9 PVD25518.1 - 0.29 11.4 0.9 0.67 10.2 0.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Kinesin PF00225.23 PVD25519.1 - 1.6e-45 155.5 0.0 3e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD25519.1 - 3.6e-10 40.0 0.0 6.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF5327 PF17261.2 PVD25519.1 - 1.4 9.7 10.0 0.12 13.2 2.4 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Adaptin_binding PF10199.9 PVD25519.1 - 3.4 8.3 15.9 2.6 8.7 1.5 3.8 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 PARM PF17061.5 PVD25520.1 - 0.25 11.5 5.7 0.29 11.3 5.7 1.1 1 0 0 1 1 1 0 PARM DUF5447 PF17525.2 PVD25520.1 - 4.7 7.7 11.7 1.1 9.8 6.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5447) Sporozoite_P67 PF05642.11 PVD25521.1 - 2.8 5.9 6.8 4.2 5.3 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CUB PF00431.20 PVD25525.1 - 3.4e-216 703.3 58.6 7.4e-19 68.1 0.1 19.4 16 3 3 19 19 19 17 CUB domain EphA2_TM PF14575.6 PVD25525.1 - 2.3e-09 38.0 0.4 0.13 13.2 0.0 3.6 3 0 0 3 3 3 3 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 PVD25525.1 - 5.2e-07 30.3 0.7 1.3 9.9 0.0 3.9 3 0 0 3 3 3 3 Cadherin cytoplasmic C-terminal Viral_DNA_Zn_bi PF03728.13 PVD25525.1 - 0.11 13.1 0.3 0.41 11.3 0.3 1.9 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain MARVEL PF01284.23 PVD25525.1 - 0.18 11.8 2.6 32 4.5 0.0 3.4 3 0 0 3 3 3 0 Membrane-associating domain DUF3147 PF11345.8 PVD25525.1 - 2 8.8 10.0 6.3 7.2 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) PTP_tm PF18861.1 PVD25525.1 - 2.4 8.1 13.2 5.5 6.9 0.7 3.5 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MscS_TM PF12794.7 PVD25525.1 - 6.2 5.6 5.8 16 4.2 0.7 2.9 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Insulin_TMD PF17870.1 PVD25525.1 - 7.1 6.8 16.7 3.4 7.8 0.8 3.7 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment CUB PF00431.20 PVD25526.1 - 1.7e-148 485.4 44.3 8.1e-19 68.0 0.3 14.8 14 1 1 15 15 15 14 CUB domain FlgT_M PF16539.5 PVD25526.1 - 0.0036 17.4 0.0 5.5 7.1 0.0 3.7 3 0 0 3 3 3 1 Flagellar assembly protein T, middle domain MORN_2 PF07661.13 PVD25526.1 - 0.048 13.9 3.2 41 4.9 0.1 4.9 4 0 0 4 4 4 0 MORN repeat variant CUB PF00431.20 PVD25527.1 - 1.6e-42 144.3 0.3 6.3e-15 55.5 0.0 3.1 3 0 0 3 3 3 3 CUB domain Amnionless PF14828.6 PVD25527.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless UL42 PF17638.2 PVD25528.1 - 0.076 13.0 0.1 0.076 13.0 0.1 2.0 2 1 1 3 3 3 0 HCMV UL42 TNFR_16_TM PF18422.1 PVD25528.1 - 0.24 11.4 0.6 0.39 10.7 0.6 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TMEM252 PF15664.5 PVD25529.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 252 family LST1 PF05083.13 PVD25529.1 - 5.1 7.4 5.7 8.3 6.8 5.6 1.5 1 1 0 1 1 1 0 LST-1 protein Shisa PF13908.6 PVD25530.1 - 0.0018 18.5 1.0 0.0018 18.5 1.0 2.7 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator MTP18 PF10558.9 PVD25530.1 - 0.0033 17.4 0.5 3.9 7.4 0.0 3.5 2 1 1 3 3 3 2 Mitochondrial 18 KDa protein (MTP18) H_PPase PF03030.16 PVD25530.1 - 0.07 11.8 0.1 0.096 11.3 0.1 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase TMEM154 PF15102.6 PVD25530.1 - 1.6 8.6 4.7 4.7 7.1 4.7 1.8 1 1 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.6 PVD25531.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 EGF PF00008.27 PVD25532.1 - 0.002 18.4 0.9 0.0047 17.2 0.9 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 PVD25532.1 - 0.029 15.0 1.5 0.16 12.6 1.5 2.4 1 0 0 1 1 1 0 Human growth factor-like EGF PMP1_2 PF08114.11 PVD25532.1 - 0.16 11.8 1.3 0.31 10.8 1.3 1.5 1 0 0 1 1 1 0 ATPase proteolipid family EGF_2 PF07974.13 PVD25532.1 - 0.18 12.2 1.2 0.46 10.9 1.2 1.7 1 0 0 1 1 1 0 EGF-like domain B12D PF06522.11 PVD25532.1 - 1.4 8.8 2.8 21 5.0 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit EGF PF00008.27 PVD25533.1 - 8.2e-20 70.8 53.7 6.1e-06 26.4 7.0 4.5 4 0 0 4 4 4 4 EGF-like domain TMEM51 PF15345.6 PVD25533.1 - 2.5e-08 34.1 4.0 0.0038 17.1 0.2 3.2 2 1 1 3 3 3 3 Transmembrane protein 51 hEGF PF12661.7 PVD25533.1 - 3.1e-08 33.9 52.5 0.00029 21.3 6.8 4.9 4 0 0 4 4 4 4 Human growth factor-like EGF EGF_2 PF07974.13 PVD25533.1 - 0.00048 20.4 63.1 0.0049 17.2 8.3 4.5 3 1 1 4 4 4 3 EGF-like domain EphA2_TM PF14575.6 PVD25533.1 - 0.0014 19.5 0.1 2.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DPPIV_N PF00930.21 PVD25533.1 - 0.0016 17.3 1.0 0.32 9.7 0.1 2.1 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Na_Ca_ex PF01699.24 PVD25533.1 - 0.002 18.1 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TMEM154 PF15102.6 PVD25533.1 - 0.01 15.7 2.2 1.6 8.7 0.3 2.8 2 1 1 3 3 3 0 TMEM154 protein family PIRT PF15099.6 PVD25533.1 - 0.022 14.4 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family YajC PF02699.15 PVD25533.1 - 0.2 11.5 0.4 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit RCR PF12273.8 PVD25533.1 - 0.24 12.0 1.9 18 6.0 0.0 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red XRCC4 PF06632.12 PVD25533.1 - 0.3 9.9 1.0 16 4.2 0.0 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 LapA_dom PF06305.11 PVD25533.1 - 0.56 10.1 2.7 13 5.7 0.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CcmD PF04995.14 PVD25533.1 - 7.2 6.8 5.1 12 6.1 0.7 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2207 PF09972.9 PVD25534.1 - 0.061 12.1 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Leader_Trp PF08255.11 PVD25534.1 - 0.16 12.0 2.1 0.35 10.9 2.1 1.6 1 0 0 1 1 1 0 Trp-operon Leader Peptide Dscam_C PF12355.8 PVD25534.1 - 1.6 9.7 7.0 0.96 10.4 4.5 1.9 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal OppC_N PF12911.7 PVD25534.1 - 5.6 7.0 5.8 4.6 7.3 0.0 2.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Sec10 PF07393.11 PVD25535.1 - 2.6e-129 432.7 6.8 1.1e-124 417.5 6.8 3.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 TPR_MLP1_2 PF07926.12 PVD25535.1 - 0.0021 18.1 0.9 0.0056 16.7 0.6 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 PVD25535.1 - 0.0063 16.5 0.8 0.36 10.8 0.8 2.8 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF2935 PF11155.8 PVD25535.1 - 0.032 14.6 0.1 1.8 8.9 0.0 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) ApoLp-III PF07464.11 PVD25535.1 - 0.072 13.2 1.9 1.2 9.3 0.6 3.4 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF2458 PF10454.9 PVD25535.1 - 0.35 10.5 5.0 0.31 10.7 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) AAA PF00004.29 PVD25536.1 - 2.9e-22 79.5 1.3 1.1e-21 77.6 0.5 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PVD25536.1 - 1.7e-10 40.7 0.2 3.2e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PVD25536.1 - 4.6e-09 35.9 0.4 8.9e-09 35.0 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_OB_N PF17758.1 PVD25536.1 - 0.0044 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_2 PF07724.14 PVD25536.1 - 0.0054 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) p31comet PF06581.12 PVD25537.1 - 1.6e-20 73.4 1.5 1.8e-19 70.0 0.3 2.1 2 0 0 2 2 2 2 Mad1 and Cdc20-bound-Mad2 binding NYN_YacP PF05991.11 PVD25537.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 YacP-like NYN domain KH_8 PF17903.1 PVD25538.1 - 0.00037 20.5 1.2 0.0019 18.3 0.1 2.4 2 0 0 2 2 2 1 Krr1 KH1 domain PhetRS_B1 PF18262.1 PVD25538.1 - 0.1 12.8 0.1 0.67 10.2 0.0 2.3 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain dsDNA_bind PF01984.20 PVD25538.1 - 0.15 12.3 2.7 0.33 11.3 2.7 1.7 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Coiled-coil_56 PF09813.9 PVD25538.1 - 0.76 9.9 4.5 0.32 11.1 0.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 CPBP PF02517.16 PVD25539.1 - 5.8e-16 58.7 8.1 5.8e-16 58.7 8.1 2.0 3 0 0 3 3 3 1 CPBP intramembrane metalloprotease Hemocyanin_N PF03722.14 PVD25539.1 - 0.057 13.9 0.2 0.18 12.4 0.0 1.8 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain CARD_2 PF16739.5 PVD25543.1 - 3.7e-05 23.6 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD PF00619.21 PVD25543.1 - 0.0098 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain ABC_tran_CTD PF16326.5 PVD25543.1 - 0.025 14.8 0.7 0.25 11.6 0.2 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF5519 PF17648.1 PVD25543.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) ParB_C PF18064.1 PVD25543.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal DUF5082 PF16888.5 PVD25543.1 - 0.13 12.5 0.0 5.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.12 PVD25543.1 - 0.76 10.4 3.4 15 6.3 0.2 2.8 3 0 0 3 3 3 0 SlyX Lig_chan-Glu_bd PF10613.9 PVD25544.1 - 1.8e-18 66.8 0.0 5.2e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD25544.1 - 4.3e-10 39.4 0.0 2.1e-09 37.2 0.0 2.2 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 adh_short PF00106.25 PVD25545.1 - 1.2e-20 73.8 0.9 2.2e-12 46.8 0.0 3.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD25545.1 - 5.4e-12 45.8 0.1 2.1e-07 30.7 0.0 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ECH_1 PF00378.20 PVD25546.1 - 2.4e-48 164.6 0.1 4.2e-48 163.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD25546.1 - 2.3e-27 96.4 0.1 1.8e-23 83.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase BACK PF07707.15 PVD25547.1 - 1.3e-21 76.6 1.0 1.3e-21 76.6 1.0 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD25547.1 - 1.8e-18 65.8 14.3 3.6e-08 32.8 0.0 6.1 5 2 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD25547.1 - 2.3e-17 62.6 1.8 0.0004 20.6 0.0 5.1 4 1 1 5 5 5 4 Kelch motif BTB PF00651.31 PVD25547.1 - 3.6e-17 62.6 0.3 1.1e-16 61.1 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 PVD25547.1 - 2.5e-12 46.2 6.4 1.8e-05 24.5 0.0 4.9 4 2 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 PVD25547.1 - 4.7e-09 36.1 5.6 0.057 13.4 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD25547.1 - 6.5e-06 26.3 5.8 0.0013 18.9 0.1 4.2 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD25547.1 - 0.0016 18.3 3.3 0.23 11.5 0.0 3.6 3 0 0 3 3 3 1 Kelch motif DUF3342 PF11822.8 PVD25547.1 - 0.0091 16.2 0.4 0.029 14.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) NFACT-R_1 PF05670.13 PVD25548.1 - 9.3e-35 119.6 0.0 9.3e-35 119.6 0.0 2.8 3 1 0 3 3 3 1 NFACT protein RNA binding domain NFACT-C PF11923.8 PVD25548.1 - 5.3e-31 106.7 0.1 5.3e-31 106.7 0.1 2.8 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 PVD25548.1 - 1e-30 106.9 9.4 1e-30 106.9 9.4 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Phage_CP76 PF06892.11 PVD25548.1 - 0.065 12.8 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) Fructosamin_kin PF03881.14 PVD25549.1 - 3.2e-25 88.9 2.3 4.5e-25 88.4 1.1 1.6 1 1 1 2 2 2 1 Fructosamine kinase APH PF01636.23 PVD25549.1 - 0.00019 21.4 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mito_carr PF00153.27 PVD25551.1 - 4.8e-40 135.4 0.2 1.6e-20 72.8 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein CUB PF00431.20 PVD25552.1 - 1.7e-51 173.2 3.3 1.1e-11 45.0 0.0 5.3 4 1 1 5 5 5 5 CUB domain Kunitz_BPTI PF00014.23 PVD25553.1 - 1.3e-18 66.9 4.6 2e-18 66.4 4.6 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Dak2 PF02734.17 PVD25553.1 - 0.014 15.3 0.3 0.024 14.6 0.3 1.3 1 0 0 1 1 1 0 DAK2 domain THEG4 PF15834.5 PVD25553.1 - 0.021 14.8 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 Peptidase_S46 PF10459.9 PVD25553.1 - 1.4 7.5 5.6 1.1 7.8 3.3 1.7 1 1 1 2 2 2 0 Peptidase S46 2OG-FeII_Oxy_3 PF13640.6 PVD25554.1 - 2.3e-20 73.3 0.0 6.9e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PVD25554.1 - 2.9e-11 43.9 0.0 7.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 PVD25554.1 - 1.8e-09 37.6 14.1 5.6e-09 36.0 14.1 1.9 1 0 0 1 1 1 1 MYND finger tRNA-synt_1c PF00749.21 PVD25555.1 - 1.5e-112 375.5 1.1 1.5e-112 375.5 1.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 PVD25555.1 - 2.3e-72 239.0 44.0 1.1e-20 73.5 2.2 5.0 5 0 0 5 5 5 4 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 PVD25555.1 - 3.1e-31 108.6 0.4 8.3e-31 107.2 0.4 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 PVD25555.1 - 1.9e-20 72.8 0.2 5.2e-20 71.4 0.2 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 PVD25555.1 - 1.1e-18 67.8 0.0 2.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PVD25555.1 - 1.6e-18 66.7 0.2 8.8e-18 64.2 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain GST_C_3 PF14497.6 PVD25555.1 - 2e-05 24.7 0.0 0.00012 22.2 0.0 2.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD25555.1 - 0.0011 19.1 0.0 0.007 16.6 0.0 2.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD25555.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CK_II_beta PF01214.18 PVD25555.1 - 0.051 13.4 0.6 0.44 10.3 0.1 2.3 1 1 1 2 2 2 0 Casein kinase II regulatory subunit HSD3 PF15244.6 PVD25556.1 - 1.4e-44 153.3 5.9 2.9e-26 93.0 4.2 2.5 2 0 0 2 2 2 2 Spermatogenesis-associated protein 7, or HSD3 zf-RING_2 PF13639.6 PVD25557.1 - 1.4e-10 41.4 10.0 2.6e-10 40.5 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD25557.1 - 2.5e-09 37.3 7.0 6.3e-09 36.0 7.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PVD25557.1 - 7.3e-08 32.2 10.0 1.4e-07 31.3 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD25557.1 - 5e-07 29.5 9.1 9.4e-07 28.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD25557.1 - 2.3e-06 27.5 5.9 4.6e-06 26.5 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD25557.1 - 1.3e-05 24.9 5.4 3.1e-05 23.7 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PVD25557.1 - 2.5e-05 23.8 3.7 4.9e-05 22.9 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 PVD25557.1 - 0.00024 21.0 8.2 0.00048 20.0 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PVD25557.1 - 0.00041 20.0 5.0 0.00041 20.0 5.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 PVD25557.1 - 0.0016 18.2 5.9 0.003 17.4 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD25557.1 - 0.026 14.6 6.2 0.17 12.0 6.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 PVD25557.1 - 0.062 13.4 3.9 0.15 12.2 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger Zf_RING PF16744.5 PVD25557.1 - 0.074 13.2 2.7 0.17 12.0 2.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 PVD25557.1 - 0.091 13.1 8.3 0.16 12.3 8.3 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 PVD25557.1 - 0.11 12.7 9.0 0.22 11.7 9.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PVD25557.1 - 0.14 12.4 5.9 0.066 13.4 3.3 1.8 2 0 0 2 2 1 0 FANCL C-terminal domain FeoB_C PF07664.12 PVD25557.1 - 0.3 10.8 2.4 0.7 9.6 0.6 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus zinc-ribbons_6 PF07191.12 PVD25557.1 - 1 9.4 4.4 1.7 8.7 4.4 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.6 PVD25557.1 - 2.1 8.6 6.3 11 6.3 6.9 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING YdjO PF14169.6 PVD25557.1 - 2.9 7.7 6.5 0.8 9.5 0.5 2.7 3 0 0 3 3 3 0 Cold-inducible protein YdjO MOSC_N PF03476.16 PVD25558.1 - 2.2e-31 108.2 0.0 3.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 PVD25558.1 - 6.2e-28 97.4 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain SMK-1 PF04802.15 PVD25559.1 - 3.7e-79 265.0 9.2 1.7e-78 262.9 9.8 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MOSC PF03473.17 PVD25559.1 - 1.7e-31 108.9 0.0 3.6e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 PVD25559.1 - 3.2e-14 52.8 0.0 5.7e-13 48.8 0.0 2.5 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Ran_BP1 PF00638.18 PVD25559.1 - 0.001 19.3 0.5 0.0021 18.3 0.0 1.8 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 PVD25559.1 - 0.009 15.9 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Collagen PF01391.18 PVD25559.1 - 0.34 10.7 3.0 0.53 10.1 3.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Bromo_TP_like PF17027.5 PVD25559.1 - 1.2 9.4 11.9 2.4 8.3 0.4 3.8 4 0 0 4 4 4 0 Histone-fold protein Costars PF14705.6 PVD25560.1 - 1e-30 105.7 0.0 1.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Costars TetR_C_13 PF16925.5 PVD25560.1 - 0.13 12.2 0.1 0.78 9.7 0.1 2.1 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CUB PF00431.20 PVD25562.1 - 1e-57 193.2 11.2 1.6e-20 73.5 0.7 3.4 4 0 0 4 4 4 3 CUB domain CUB_2 PF02408.20 PVD25562.1 - 0.00043 20.0 7.3 0.14 12.0 0.2 3.2 3 0 0 3 3 3 2 CUB-like domain Insulin_TMD PF17870.1 PVD25562.1 - 0.069 13.2 2.0 0.16 12.0 2.0 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 PVD25562.1 - 0.11 12.8 0.4 0.24 11.7 0.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 PVD25562.1 - 0.13 13.2 0.1 0.34 11.8 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD25562.1 - 0.43 10.5 1.8 0.84 9.6 1.8 1.4 1 0 0 1 1 1 0 Syndecan domain VWC PF00093.18 PVD25562.1 - 1.2 9.6 9.6 4.1 7.8 0.3 3.2 3 0 0 3 3 3 0 von Willebrand factor type C domain DUF4389 PF14333.6 PVD25562.1 - 6.9 6.7 6.7 2.7 8.0 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) CUB PF00431.20 PVD25563.1 - 2.5e-41 140.5 5.2 3.6e-13 49.8 0.1 3.2 2 1 1 3 3 3 3 CUB domain TMEM154 PF15102.6 PVD25563.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 PVD25563.1 - 0.07 14.0 0.5 0.19 12.6 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 PVD25563.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_S21e PF01249.18 PVD25563.1 - 0.12 12.5 0.4 0.28 11.3 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein S21e Cadherin_C_2 PF16492.5 PVD25563.1 - 0.12 13.1 1.2 0.28 12.0 0.2 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CUB_2 PF02408.20 PVD25563.1 - 0.67 9.7 3.8 1.4 8.7 0.5 2.9 3 0 0 3 3 3 0 CUB-like domain CYYR1 PF10873.8 PVD25564.1 - 0.19 12.2 2.7 0.14 12.6 1.3 1.5 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ASC PF00858.24 PVD25564.1 - 0.2 10.6 3.4 0.23 10.4 3.4 1.2 1 1 0 1 1 1 0 Amiloride-sensitive sodium channel Ribosomal_S30 PF04758.14 PVD25566.1 - 4e-18 65.3 11.6 5.8e-18 64.8 11.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 PVD25566.1 - 8.2e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PVD25566.1 - 0.018 15.6 0.0 0.029 14.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ExoD PF06055.12 PVD25566.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Bromo_TP PF07524.13 PVD25567.1 - 8.1e-23 80.2 0.4 2.2e-22 78.9 0.2 1.7 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 PVD25567.1 - 7e-19 68.1 1.3 1.9e-18 66.8 1.3 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 PVD25567.1 - 0.0034 17.5 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Histone-fold protein CENP-S PF15630.6 PVD25567.1 - 0.014 15.7 0.1 0.18 12.2 0.0 2.2 1 1 1 2 2 2 0 CENP-S protein TFIID-31kDa PF02291.15 PVD25567.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 PVD25567.1 - 0.096 12.8 0.1 0.44 10.7 0.0 2.0 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold Methyltransf_16 PF10294.9 PVD25568.1 - 9.3e-18 64.6 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 PVD25568.1 - 8.2e-05 23.2 0.0 0.0002 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD25568.1 - 0.0006 20.5 0.1 0.0034 18.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD25568.1 - 0.003 18.2 0.0 0.028 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PVD25568.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 PVD25568.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 PVD25568.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TMEM223 PF14640.6 PVD25569.1 - 2.9e-46 157.7 0.1 3.2e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 223 Ribosomal_S30 PF04758.14 PVD25570.1 - 1e-29 102.5 11.6 1.4e-29 102.0 11.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 PVD25570.1 - 8.5e-09 35.0 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family FHA PF00498.26 PVD25571.1 - 5e-17 62.0 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 PVD25571.1 - 2.8e-09 36.7 7.1 4.5e-09 36.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD25571.1 - 5.7e-09 35.7 9.0 1.1e-08 34.8 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD25571.1 - 1.9e-08 34.5 9.1 3.3e-08 33.7 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD25571.1 - 5.1e-08 32.7 9.8 1.1e-07 31.6 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 PVD25571.1 - 6.4e-06 26.4 0.4 5.6e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 PVD25571.1 - 1.4e-05 25.3 8.4 5e-05 23.5 8.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD25571.1 - 8.8e-05 22.5 4.1 0.00018 21.4 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD25571.1 - 9.2e-05 22.5 9.7 0.00022 21.3 9.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD25571.1 - 0.00011 22.1 9.0 0.0002 21.2 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 PVD25571.1 - 0.0012 18.9 7.5 0.0025 17.9 7.5 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PVD25571.1 - 0.012 15.6 1.0 0.027 14.5 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 PVD25571.1 - 0.015 15.1 5.5 0.026 14.4 5.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PVD25571.1 - 0.019 14.8 8.5 0.036 13.9 8.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD25571.1 - 0.083 12.7 6.2 0.19 11.5 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PVD25571.1 - 0.22 11.2 5.2 0.43 10.3 5.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger DUF2236 PF09995.9 PVD25572.1 - 1.5e-15 58.0 0.0 2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) 7tm_1 PF00001.21 PVD25574.1 - 1.3e-20 73.9 10.4 1.6e-20 73.5 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sru PF10322.9 PVD25574.1 - 0.00034 20.0 9.4 0.00051 19.5 9.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru Sigma_reg_N PF13800.6 PVD25574.1 - 0.0089 16.3 0.4 1.5 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma factor regulator N-terminal Srg PF02118.21 PVD25574.1 - 0.055 13.1 16.7 0.23 11.1 16.5 2.0 1 1 0 1 1 1 0 Srg family chemoreceptor Ac76 PF05814.11 PVD25574.1 - 0.14 12.2 2.5 4.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Orf76 (Ac76) CD34_antigen PF06365.12 PVD25574.1 - 0.17 11.4 0.8 0.24 10.9 0.1 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family Orf78 PF06024.12 PVD25574.1 - 0.45 10.8 1.5 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) 7tm_1 PF00001.21 PVD25575.1 - 2.2e-07 30.5 8.5 2.7e-07 30.2 8.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD25575.1 - 6.5e-05 22.4 7.0 8.7e-05 22.0 7.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM51 PF15345.6 PVD25575.1 - 0.039 13.8 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Srg PF02118.21 PVD25575.1 - 0.065 12.9 14.0 0.12 12.0 14.0 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor TPR_17 PF13431.6 PVD25576.1 - 3.3e-09 36.5 0.6 0.16 12.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD25576.1 - 0.00028 21.4 0.0 0.33 11.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD25576.1 - 0.0006 19.4 0.0 0.17 11.6 0.0 3.5 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 PVD25576.1 - 0.0058 16.4 2.0 9.4 6.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD25576.1 - 0.015 15.4 6.7 25 5.3 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD25576.1 - 0.021 15.0 2.5 0.23 11.7 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1726 PF08351.11 PVD25576.1 - 0.072 13.0 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) DUF4735 PF15882.5 PVD25577.1 - 9.5e-63 212.3 0.4 2e-53 181.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4735) XPG_I_2 PF12813.7 PVD25577.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing E1_DerP2_DerF2 PF02221.15 PVD25578.1 - 9.2e-19 68.2 1.6 1e-18 68.0 0.6 1.6 1 1 0 1 1 1 1 ML domain PDZ_6 PF17820.1 PVD25580.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD25580.1 - 1.9e-06 28.1 0.0 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD25580.1 - 0.00024 21.4 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 PVD25580.1 - 0.046 14.1 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Gcd10p PF04189.13 PVD25581.1 - 1.9e-53 181.5 1.3 3e-53 180.9 0.2 1.8 1 1 0 1 1 1 1 Gcd10p family Guanylate_kin PF00625.21 PVD25581.1 - 6.5e-48 162.8 0.0 1.7e-47 161.4 0.0 1.8 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 PVD25581.1 - 1.9e-12 47.4 2.0 4.7e-12 46.1 2.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD25581.1 - 1e-09 38.1 0.2 5.6e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 PDZ domain L27 PF02828.16 PVD25581.1 - 8.5e-09 35.1 0.7 6.2e-08 32.3 0.1 2.7 2 0 0 2 2 2 1 L27 domain SH3_2 PF07653.17 PVD25581.1 - 9.1e-07 28.5 0.0 4e-06 26.4 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain PDZ_2 PF13180.6 PVD25581.1 - 9.4e-06 25.9 0.4 4e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 PDZ domain L27_N PF09060.10 PVD25581.1 - 6.6e-05 22.9 0.1 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 L27_N SH3_1 PF00018.28 PVD25581.1 - 0.0064 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain START PF01852.19 PVD25582.1 - 2.6e-07 30.3 0.0 7e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 START domain Lactamase_B_6 PF16661.5 PVD25583.1 - 1.9e-63 213.4 0.0 2.3e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PVD25583.1 - 2.4e-05 24.0 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD25583.1 - 6e-05 23.1 0.1 7.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 PVD25583.1 - 0.00027 20.2 0.0 0.00072 18.8 0.0 1.7 1 1 0 1 1 1 1 Putative beta-lactamase-like family CPSF100_C PF13299.6 PVD25584.1 - 4.7e-35 121.3 0.1 1.5e-34 119.6 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 PVD25584.1 - 6.5e-21 74.7 0.0 1.5e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 PVD25584.1 - 7.7e-14 51.4 0.0 1.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain HTH_Tnp_IS630 PF01710.16 PVD25584.1 - 0.046 13.8 0.2 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 Transposase Adap_comp_sub PF00928.21 PVD25586.1 - 7.1e-48 163.3 0.1 1.1e-47 162.6 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Death PF00531.22 PVD25588.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Death domain Cep57_CLD_2 PF14197.6 PVD25588.1 - 0.003 17.6 5.9 0.0067 16.5 0.3 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 UPF0449 PF15136.6 PVD25588.1 - 0.042 14.3 1.8 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DegS PF05384.11 PVD25588.1 - 0.053 13.0 8.7 0.13 11.7 1.5 2.4 1 1 1 2 2 2 0 Sensor protein DegS Phage_GP20 PF06810.11 PVD25588.1 - 0.074 12.8 3.1 0.15 11.9 1.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Nup54 PF13874.6 PVD25588.1 - 0.13 12.4 1.0 0.43 10.7 1.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.9 PVD25588.1 - 0.13 12.3 6.8 0.15 12.1 1.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 PVD25588.1 - 0.2 11.7 6.2 5.8 7.0 1.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 PVD25588.1 - 0.31 11.3 3.3 2 8.7 0.3 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 PVD25588.1 - 0.33 11.0 4.3 8.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 PVD25588.1 - 0.63 9.4 6.3 1.3 8.3 4.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 PVD25588.1 - 0.7 10.4 5.5 1.4 9.4 4.5 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 PVD25588.1 - 0.72 10.0 5.6 3.3 7.9 1.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 PVD25588.1 - 1.6 9.4 9.2 3.5 8.3 0.6 3.6 3 0 0 3 3 3 0 SlyX PKcGMP_CC PF16808.5 PVD25588.1 - 1.8 8.5 14.5 2.7 7.9 1.6 3.4 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Val_tRNA-synt_C PF10458.9 PVD25588.1 - 2.1 8.7 5.1 0.77 10.1 1.3 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm HMMR_N PF15905.5 PVD25588.1 - 2.2 7.6 10.4 2 7.8 0.3 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Csm1_N PF18504.1 PVD25588.1 - 2.5 8.5 6.2 7.8 6.9 1.4 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Spectrin PF00435.21 PVD25588.1 - 3 8.4 6.0 9.9 6.7 0.5 2.7 3 0 0 3 3 3 0 Spectrin repeat DivIC PF04977.15 PVD25588.1 - 3.3 7.6 5.6 14 5.6 1.5 2.6 3 0 0 3 3 3 0 Septum formation initiator NBP1 PF08537.10 PVD25588.1 - 6.9 6.0 7.5 2.4 7.5 2.9 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 LRR_4 PF12799.7 PVD25589.1 - 8.3e-40 134.1 87.3 3.3e-05 24.2 0.0 13.6 11 1 0 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD25589.1 - 2e-39 134.9 43.5 3.3e-12 46.3 3.1 8.1 4 3 2 7 7 7 6 Leucine-rich repeat LRR_8 PF13855.6 PVD25589.1 - 4e-30 103.4 91.4 9.8e-09 34.8 0.6 13.3 8 4 7 15 15 15 13 Leucine rich repeat LRR_2 PF07723.13 PVD25589.1 - 0.018 15.7 5.6 13 6.7 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich Repeat DUF745 PF05335.13 PVD25589.1 - 0.49 10.1 2.3 0.92 9.2 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Glu-tRNAGln PF02686.15 PVD25590.1 - 0.074 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit PIP49_C PF12260.8 PVD25591.1 - 3.9e-06 26.6 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 PVD25591.1 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD25591.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EB PF01683.18 PVD25591.1 - 1.2 9.5 3.5 1.2 9.4 0.3 2.3 2 0 0 2 2 2 0 EB module WD40 PF00400.32 PVD25592.1 - 1.8e-25 88.7 21.3 0.00075 20.3 0.6 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25592.1 - 9.5e-09 35.4 3.3 0.033 14.5 0.1 5.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD25592.1 - 4.1e-07 29.6 1.7 0.0041 16.5 0.1 3.0 1 1 2 3 3 3 3 WD40-like domain F-box PF00646.33 PVD25592.1 - 5.4e-06 26.1 2.7 9.1e-06 25.4 1.7 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PVD25592.1 - 7.9e-06 25.7 0.8 1.4e-05 24.9 0.8 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 PVD25592.1 - 6.3e-05 21.8 9.5 0.92 8.1 0.2 4.9 3 3 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PVD25592.1 - 0.0022 17.0 1.5 0.02 13.9 0.1 2.7 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 PVD25592.1 - 0.006 16.2 2.1 0.11 12.1 1.5 2.2 1 1 2 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.6 PVD25592.1 - 0.024 14.6 0.2 1.8 8.6 0.0 3.4 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 PVD25592.1 - 0.041 13.8 0.1 0.41 10.5 0.0 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 PVD25592.1 - 0.088 12.8 0.0 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4381 PF14316.6 PVD25594.1 - 0.0075 16.5 0.1 0.0095 16.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) 7tm_1 PF00001.21 PVD25595.1 - 5.7e-25 88.1 23.1 7e-25 87.8 23.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD25595.1 - 4.3e-07 29.8 21.9 5.9e-07 29.4 21.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD25595.1 - 0.00014 21.4 24.8 0.00072 19.0 25.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4006 PF13179.6 PVD25595.1 - 0.12 12.3 1.1 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Galactosyl_T PF01762.21 PVD25597.1 - 0.0036 17.2 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 PVD25598.1 - 1.2e-07 31.7 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Lin-8 PF03353.15 PVD25599.1 - 0.87 9.1 10.4 1.4 8.5 10.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MOZ_SAS PF01853.18 PVD25600.1 - 2e-84 281.7 0.0 3.7e-84 280.8 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PVD25600.1 - 1.8e-24 85.1 4.5 1.8e-24 85.1 4.5 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 PVD25600.1 - 1.5e-19 69.6 0.0 3.2e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_16 PF13191.6 PVD25600.1 - 0.00027 21.4 0.1 0.0016 18.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 PVD25600.1 - 0.004 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NERD PF08378.11 PVD25600.1 - 0.014 15.9 0.0 0.043 14.3 0.0 1.9 1 0 0 1 1 1 0 Nuclease-related domain AAA_22 PF13401.6 PVD25600.1 - 0.022 15.0 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Acetyltransf_7 PF13508.7 PVD25600.1 - 0.059 13.8 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TsaE PF02367.17 PVD25600.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L39 PF00832.20 PVD25600.1 - 1.7 8.4 5.3 3.5 7.3 1.7 2.5 2 0 0 2 2 2 0 Ribosomal L39 protein Ras PF00071.22 PVD25601.1 - 1.5e-30 105.9 0.0 1.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25601.1 - 4.4e-10 39.8 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD25602.1 - 7.3e-31 106.9 0.0 1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25602.1 - 8.8e-15 55.0 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PVD25602.1 - 6.4e-07 29.4 0.0 9.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD25602.1 - 0.00045 19.8 0.2 0.0015 18.1 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 PVD25602.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rota_Capsid_VP6 PF00980.17 PVD25602.1 - 0.23 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 GBP_C PF02841.14 PVD25603.1 - 0.033 13.6 5.1 0.059 12.8 5.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ZapB PF06005.12 PVD25603.1 - 0.038 14.4 4.5 0.31 11.5 4.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB CdvA PF18822.1 PVD25603.1 - 0.069 13.0 4.9 0.042 13.7 1.9 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TSNAXIP1_N PF15739.5 PVD25603.1 - 0.79 10.1 6.2 0.22 11.9 2.8 1.9 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF724 PF05266.14 PVD25603.1 - 5.9 6.7 9.5 0.98 9.2 5.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Img2 PF05046.14 PVD25604.1 - 6.9e-18 64.7 0.1 1.4e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) APC1_C PF18122.1 PVD25604.1 - 1.9e-09 37.7 0.8 5.5e-06 26.4 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 PVD25604.1 - 8e-09 36.1 6.0 6.3e-08 33.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 PVD25604.1 - 0.0038 17.6 5.7 19 5.9 0.6 5.0 4 0 0 4 4 4 2 Proteasome/cyclosome repeat AbLIM_anchor PF16182.5 PVD25604.1 - 1.8 8.3 6.0 3.2 7.5 6.0 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM FYVE PF01363.21 PVD25605.1 - 4.1e-11 42.8 8.0 4.1e-11 42.8 8.0 2.4 2 0 0 2 2 2 1 FYVE zinc finger zf-B_box PF00643.24 PVD25605.1 - 0.00074 19.6 6.4 0.00074 19.6 6.4 2.9 2 1 1 3 3 3 2 B-box zinc finger AAA_lid_9 PF17871.1 PVD25605.1 - 0.043 13.7 1.0 0.043 13.7 1.0 3.1 3 2 0 3 3 3 0 AAA lid domain GTP_EFTU PF00009.27 PVD25606.1 - 8.7e-27 93.9 0.0 1.7e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PVD25606.1 - 1.9e-07 31.3 0.4 5.4e-07 29.9 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 PVD25606.1 - 0.00039 20.7 0.0 0.00077 19.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 PVD25606.1 - 0.00046 20.2 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PVD25606.1 - 0.0045 16.7 0.1 11 5.8 0.0 3.4 1 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 PVD25606.1 - 0.0077 15.8 0.1 4.2 6.9 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD25606.1 - 0.012 15.6 0.0 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 PVD25606.1 - 0.021 14.6 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 PVD25606.1 - 0.099 12.7 0.3 4 7.5 0.1 2.4 1 1 0 2 2 2 0 Dynamin family Arf PF00025.21 PVD25606.1 - 0.14 11.6 0.0 10 5.6 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family Lung_7-TM_R PF06814.13 PVD25607.1 - 1.6e-84 283.7 19.1 2.1e-84 283.3 19.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PVD25607.1 - 0.039 13.4 15.5 0.014 14.8 12.6 1.7 1 1 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Ndc80_HEC PF03801.13 PVD25607.1 - 0.66 9.6 2.6 0.4 10.3 0.3 1.8 2 0 0 2 2 2 0 HEC/Ndc80p family GCD14 PF08704.10 PVD25608.1 - 2.2e-90 302.6 0.2 2.8e-89 299.1 0.2 1.9 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PVD25608.1 - 6.9e-10 38.9 0.0 9.4e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD25608.1 - 0.00078 20.1 0.0 0.0015 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD25608.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 PVD25608.1 - 0.012 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 PVD25608.1 - 0.021 14.6 0.9 0.073 12.9 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_12 PF08242.12 PVD25608.1 - 0.045 14.5 0.0 0.083 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PVD25608.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SRF-TF PF00319.18 PVD25609.1 - 3.6e-06 26.4 1.7 6e-06 25.6 1.7 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_M28 PF04389.17 PVD25610.1 - 4.6e-59 199.4 0.0 7e-32 110.7 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M28 PriCT_2 PF08707.11 PVD25610.1 - 0.0057 17.0 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Primase C terminal 2 (PriCT-2) Nicastrin PF05450.15 PVD25610.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Polysacc_lyase PF14099.6 PVD25612.1 - 0.00086 19.2 1.2 0.0014 18.5 1.2 1.5 1 1 0 1 1 1 1 Polysaccharide lyase CC2D2AN-C2 PF15625.6 PVD25612.1 - 0.21 11.3 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain CBF PF03914.17 PVD25613.1 - 2e-42 145.2 0.1 5.2e-42 143.8 0.1 1.8 1 0 0 1 1 1 1 CBF/Mak21 family Gag_p30 PF02093.16 PVD25613.1 - 0.056 13.0 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Gag P30 core shell protein Phosphorylase PF00343.20 PVD25614.1 - 0 1013.2 1.2 2.7e-131 439.2 0.1 3.0 1 1 2 3 3 3 3 Carbohydrate phosphorylase cNMP_binding PF00027.29 PVD25615.1 - 1.2e-17 63.8 0.1 2.1e-06 27.7 0.0 4.5 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain SVIP PF15811.5 PVD25615.1 - 0.65 10.5 3.0 0.63 10.5 0.7 2.1 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Glyco_hydro_10 PF00331.20 PVD25617.1 - 4.2e-30 105.0 0.3 1.3e-23 83.6 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD25617.1 - 6.5e-11 42.6 0.1 3.8e-10 40.2 0.0 2.3 2 1 0 2 2 2 1 Carbohydrate binding domain Poxvirus_B22R_N PF13169.6 PVD25617.1 - 0.027 14.9 0.1 0.056 13.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal Tautomerase_2 PF14552.6 PVD25617.1 - 0.074 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Glyco_hydro_10 PF00331.20 PVD25618.1 - 4.9e-30 104.8 0.0 6.1e-24 84.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.20 PVD25619.1 - 3.5e-36 125.0 0.0 8.1e-17 61.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD25619.1 - 9.7e-14 51.8 0.0 3.3e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_10 PF00331.20 PVD25620.1 - 1.5e-42 145.9 0.8 2.8e-42 145.0 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD25620.1 - 2.7e-12 47.1 0.0 1.3e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain DnaJ PF00226.31 PVD25622.1 - 1.3e-18 66.9 0.3 1.3e-18 66.9 0.3 1.7 2 0 0 2 2 2 1 DnaJ domain Transp_cyt_pur PF02133.15 PVD25622.1 - 0.26 10.0 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin CutA1 PF03091.15 PVD25623.1 - 3.2e-39 132.8 0.0 3.6e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein HPD PF05044.12 PVD25624.1 - 4.8e-32 111.0 1.2 6.5e-32 110.5 1.2 1.1 1 0 0 1 1 1 1 Homeo-prospero domain HeLo PF14479.6 PVD25625.1 - 0.98 9.2 7.4 0.19 11.6 0.8 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation Biotin_lipoyl PF00364.22 PVD25626.1 - 6.6e-20 70.7 1.8 1.1e-19 70.0 1.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PVD25626.1 - 2.5e-07 30.4 0.7 4.2e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 PVD25626.1 - 0.0043 16.3 0.1 0.008 15.4 0.0 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 PVD25626.1 - 0.021 14.8 0.9 0.15 12.0 0.3 2.4 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.7 PVD25626.1 - 0.022 13.5 0.1 3.3 6.3 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.16 PVD25626.1 - 0.05 13.7 0.2 1.4 9.1 0.0 2.4 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 PVD25626.1 - 0.15 12.0 0.3 0.25 11.3 0.3 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein PYNP_C PF07831.13 PVD25626.1 - 0.17 11.5 1.2 4.2 7.1 0.1 2.9 2 1 1 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain 2-oxoacid_dh PF00198.23 PVD25627.1 - 1.5e-60 204.6 0.3 2.9e-36 125.1 0.0 2.0 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Lipid_DES PF08557.10 PVD25630.1 - 2.1e-23 81.5 1.3 4.8e-23 80.4 1.3 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 PVD25630.1 - 1e-13 51.8 3.4 1.3e-13 51.4 3.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase zf-C2H2 PF00096.26 PVD25631.1 - 8e-17 60.7 26.2 3e-05 24.2 0.4 4.8 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD25631.1 - 1.1e-14 54.0 23.0 8.5e-07 29.1 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD25631.1 - 1.5e-11 44.1 20.7 0.036 14.9 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD25631.1 - 0.011 16.0 10.9 0.27 11.6 0.6 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD25631.1 - 0.022 15.1 4.5 1.8 9.1 0.5 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.21 PVD25631.1 - 0.024 14.9 1.5 0.024 14.9 1.5 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Raffinose_syn PF05691.12 PVD25631.1 - 0.038 11.8 0.0 0.059 11.2 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_aberr PF17017.5 PVD25631.1 - 0.044 13.9 7.5 4.1 7.5 0.1 3.3 1 1 1 3 3 3 0 Aberrant zinc-finger CCAP PF11105.8 PVD25631.1 - 0.11 12.4 4.0 1.6 8.7 0.8 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-TRAF PF02176.18 PVD25631.1 - 0.15 12.8 12.5 8.8 7.1 0.1 3.4 1 1 2 3 3 3 0 TRAF-type zinc finger CHORD PF04968.12 PVD25631.1 - 0.34 11.6 11.3 12 6.7 2.1 3.6 1 1 3 4 4 4 0 CHORD FOXP-CC PF16159.5 PVD25631.1 - 0.37 11.5 2.4 21 5.9 0.9 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 PVD25631.1 - 0.69 9.7 7.9 5.3 6.9 0.4 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type Transpos_assoc PF13963.6 PVD25631.1 - 1.9 8.9 7.2 7.5 7.0 0.1 3.4 3 1 0 3 3 3 0 Transposase-associated domain zf_UBZ PF18439.1 PVD25631.1 - 1.9 8.1 3.8 4.5 6.9 0.2 3.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 PVD25631.1 - 4.3 7.7 6.6 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon Paf1 PF03985.13 PVD25632.1 - 1.8e-143 478.6 22.1 1.8e-143 478.6 22.1 1.8 1 1 1 2 2 2 1 Paf1 PKD_3 PF16820.5 PVD25632.1 - 0.017 14.8 1.7 0.067 13.0 0.6 2.3 2 0 0 2 2 2 0 PKD-like domain Med29 PF11568.8 PVD25633.1 - 6.7e-38 130.0 0.2 9.4e-38 129.6 0.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 APG5 PF04106.12 PVD25633.1 - 0.048 13.2 1.0 0.053 13.1 1.0 1.2 1 1 0 1 1 1 0 Autophagy protein Apg5 Reprolysin_5 PF13688.6 PVD25634.1 - 2.5e-19 70.2 0.4 4.2e-19 69.5 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD25634.1 - 1.1e-12 48.3 0.8 1.5e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD25634.1 - 2.1e-11 44.4 0.3 3.5e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD25634.1 - 4e-09 36.7 1.2 4e-09 36.7 1.2 2.3 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD25634.1 - 0.00017 21.3 0.5 0.00025 20.7 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD25634.1 - 0.01 16.6 6.7 0.01 16.6 6.7 2.2 2 0 0 2 2 2 0 Disintegrin Crystall PF00030.19 PVD25634.1 - 0.028 14.6 0.2 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 Beta/Gamma crystallin Peptidase_M57 PF12388.8 PVD25634.1 - 1.9 8.1 5.8 0.075 12.6 0.3 1.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Kelch_3 PF13415.6 PVD25635.1 - 1.7e-37 127.0 9.1 2e-07 31.1 0.1 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD25635.1 - 4.7e-35 119.3 5.1 1.5e-05 24.9 0.0 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD25635.1 - 8.3e-32 108.7 0.1 2.5e-05 24.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD25635.1 - 4.2e-20 70.9 11.5 0.00021 21.1 0.2 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.25 PVD25635.1 - 1.7e-19 69.1 12.0 1.4e-05 24.6 0.2 6.5 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 PVD25635.1 - 2.3e-15 56.2 11.3 0.094 13.0 0.0 6.6 5 1 1 6 6 6 6 Kelch motif RAG2 PF03089.14 PVD25635.1 - 0.061 12.3 0.1 5 6.0 0.0 3.5 3 1 1 4 4 4 0 Recombination activating protein 2 TauD PF02668.16 PVD25636.1 - 4e-36 125.2 0.0 5.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 PVD25636.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 CsiD LRR_6 PF13516.6 PVD25637.1 - 3.9e-14 51.4 26.7 0.0035 17.3 0.1 8.7 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 PVD25637.1 - 1.6e-05 25.2 16.1 0.0027 18.1 0.3 4.9 3 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD25637.1 - 0.088 12.6 17.8 3.9 7.3 2.5 5.7 3 2 1 4 4 4 0 Leucine rich repeat CwsA PF10814.8 PVD25637.1 - 0.34 11.1 2.9 0.76 10.0 2.9 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA LRR_1 PF00560.33 PVD25637.1 - 0.8 10.5 15.1 51 5.0 0.2 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 PVD25638.1 - 2.9e-17 62.9 0.0 1.1e-16 61.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25638.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD25638.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PVD25638.1 - 0.011 14.5 0.3 0.022 13.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase BCS1_N PF08740.11 PVD25639.1 - 1.5e-44 152.3 0.8 2.2e-44 151.7 0.8 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PVD25639.1 - 1.2e-09 38.7 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EAL PF00563.20 PVD25639.1 - 0.11 12.0 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 EAL domain DEAD PF00270.29 PVD25641.1 - 8.4e-34 116.9 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD25641.1 - 1.5e-10 41.4 0.4 1.8e-06 28.3 0.1 3.0 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 PVD25641.1 - 0.006 16.6 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PVD25641.1 - 0.0082 16.4 0.1 0.031 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain LpxB PF02684.15 PVD25641.1 - 0.14 10.9 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PhoH PF02562.16 PVD25641.1 - 0.14 11.5 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Globin PF00042.22 PVD25642.1 - 1.3e-06 28.9 0.0 1.9e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Globin Globin PF00042.22 PVD25643.1 - 5.6e-15 55.9 0.0 9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Globin UPF0552 PF10574.9 PVD25644.1 - 2.1e-56 190.8 0.0 2.4e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin ATP-synt_D PF01813.17 PVD25645.1 - 1.1e-74 250.5 9.8 1.6e-74 250.0 9.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF1796 PF08795.10 PVD25645.1 - 0.43 10.5 2.4 0.73 9.8 2.4 1.6 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Spectrin PF00435.21 PVD25646.1 - 0 1448.0 356.9 1.6e-23 83.2 2.6 33.4 32 2 0 32 32 32 31 Spectrin repeat CH PF00307.31 PVD25646.1 - 6e-45 151.9 8.3 2e-24 85.9 0.0 5.2 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.6 PVD25646.1 - 4.7e-18 65.7 0.3 3.3e-17 63.0 0.3 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 PVD25646.1 - 2.1e-10 41.0 2.7 1.2e-09 38.6 0.1 3.5 3 0 0 3 3 3 1 PH domain SH3_9 PF14604.6 PVD25646.1 - 3.9e-06 26.6 0.0 9.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD25646.1 - 8.4e-06 25.3 0.4 2.6e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 PVD25646.1 - 0.00012 22.2 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 PVD25646.1 - 0.00071 19.6 0.2 0.021 14.9 0.0 2.8 2 0 0 2 2 2 1 SH3 domain CAMSAP_CH PF11971.8 PVD25646.1 - 0.00085 19.1 0.0 0.064 13.1 0.0 3.2 2 0 0 2 2 2 1 CAMSAP CH domain AntA PF08346.12 PVD25646.1 - 0.0035 17.9 2.0 0.032 14.8 0.5 3.7 2 0 0 2 2 2 1 AntA/AntB antirepressor DUF5616 PF18481.1 PVD25646.1 - 0.037 14.3 10.1 3.6 7.9 0.1 7.0 7 1 0 7 7 7 0 Domain of unknown function (DUF5616) ABC_tran PF00005.27 PVD25647.1 - 1.9e-30 106.2 0.0 3.8e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PVD25647.1 - 1.9e-28 99.6 25.4 2.9e-28 99.0 25.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PVD25647.1 - 1.2e-10 41.7 0.2 7.9e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD25647.1 - 2.6e-05 23.8 0.0 0.053 13.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PVD25647.1 - 0.00038 21.0 0.1 0.00077 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PVD25647.1 - 0.00057 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD25647.1 - 0.00094 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane PF01061.24 PVD25647.1 - 0.0096 15.4 20.0 0.027 13.9 20.0 1.7 1 0 0 1 1 1 1 ABC-2 type transporter AAA_15 PF13175.6 PVD25647.1 - 0.028 14.1 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DLIC PF05783.11 PVD25647.1 - 0.029 13.2 0.0 0.062 12.1 0.0 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 PVD25647.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.25 PVD25648.1 - 9.4e-56 189.1 0.0 7.8e-55 186.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 PVD25648.1 - 1e-50 172.9 0.4 2.2e-50 171.8 0.0 1.7 2 0 0 2 2 2 1 CNH domain Pkinase_Tyr PF07714.17 PVD25648.1 - 1.9e-33 115.9 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_tran PF00005.27 PVD25648.1 - 2.6e-21 76.6 0.0 5.6e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PVD25648.1 - 6.4e-19 68.3 19.9 1e-18 67.6 19.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PVD25648.1 - 3.6e-09 36.9 0.0 3e-07 30.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase_fungal PF17667.1 PVD25648.1 - 0.00099 18.0 0.0 0.0026 16.6 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase RsgA_GTPase PF03193.16 PVD25648.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Kinase-like PF14531.6 PVD25648.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like AAA_16 PF13191.6 PVD25648.1 - 0.076 13.4 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain eIF_4EBP PF05456.11 PVD25648.1 - 0.13 12.3 1.4 18 5.3 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) AAA_30 PF13604.6 PVD25648.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PVD25649.1 - 3.4e-41 141.3 1.1 3e-34 118.6 0.4 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25649.1 - 9.7e-22 77.5 1.8 7.9e-20 71.2 0.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD25649.1 - 6.6e-06 25.3 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PVD25649.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 PVD25649.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD25649.1 - 0.083 12.2 0.3 0.15 11.4 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PVD25649.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase BRO1 PF03097.18 PVD25650.1 - 2.6e-25 89.0 0.3 3.1e-25 88.8 0.3 1.0 1 0 0 1 1 1 1 BRO1-like domain PAP1 PF08601.10 PVD25651.1 - 2.3 7.9 12.3 1.3 8.7 1.1 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 Mito_carr PF00153.27 PVD25652.1 - 3.7e-55 183.8 0.6 2.6e-20 72.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc34 PF05158.12 PVD25653.1 - 6.8e-68 229.5 7.6 1e-61 209.2 6.4 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RPA_C PF08784.11 PVD25653.1 - 4.9e-06 27.1 3.5 0.16 12.7 0.1 3.5 3 1 0 3 3 3 2 Replication protein A C terminal TrmB PF01978.19 PVD25653.1 - 6.5e-05 22.7 0.2 0.0005 19.9 0.1 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 PVD25653.1 - 0.013 15.1 0.8 0.013 15.1 0.8 3.1 4 1 0 4 4 4 0 Winged helix-turn-helix DNA-binding DUF4279 PF14106.6 PVD25653.1 - 0.013 15.7 0.0 0.28 11.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Rrf2 PF02082.20 PVD25653.1 - 0.017 15.5 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_47 PF16221.5 PVD25653.1 - 0.071 12.7 0.2 0.22 11.1 0.2 1.8 1 0 0 1 1 1 0 winged helix-turn-helix HTH_45 PF14947.6 PVD25653.1 - 0.085 12.9 2.2 0.36 10.9 0.5 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix GST_N PF02798.20 PVD25654.1 - 1.6e-10 41.2 0.0 3.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD25654.1 - 4.2e-10 39.8 0.0 1.3e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PVD25654.1 - 4.3e-10 39.9 0.0 8.9e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD25654.1 - 7.6e-10 38.9 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD25654.1 - 1.2e-05 25.4 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PVD25654.1 - 0.00054 20.1 0.0 0.0023 18.1 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 PVD25654.1 - 0.0028 17.7 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD25655.1 - 6.3e-16 58.6 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD25655.1 - 7.1e-15 55.1 0.0 1.5e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD25655.1 - 2e-14 53.7 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD25655.1 - 1.3e-07 31.7 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PVD25655.1 - 4.6e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 PVD25655.1 - 0.00043 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD25655.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RPAP1_C PF08620.10 PVD25656.1 - 4.3e-26 90.8 0.1 9.8e-26 89.7 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 PVD25656.1 - 1.6e-16 59.8 5.7 1.6e-16 59.8 5.7 2.4 3 0 0 3 3 3 1 RPAP1-like, N-terminal LRR_6 PF13516.6 PVD25658.1 - 1.1e-27 93.6 36.5 2.4e-07 30.3 0.2 10.1 10 0 0 10 10 10 7 Leucine Rich repeat LRR_8 PF13855.6 PVD25658.1 - 1.2e-06 28.1 25.4 0.72 9.7 0.4 7.6 3 2 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 PVD25658.1 - 0.007 16.7 11.9 1.3e+02 3.7 0.1 8.6 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_4 PF12799.7 PVD25658.1 - 0.013 15.9 27.3 2.8 8.5 1.3 7.2 4 2 6 10 10 10 0 Leucine Rich repeats (2 copies) HypF_C PF17788.1 PVD25658.1 - 0.021 15.5 0.9 0.11 13.2 0.5 2.3 2 0 0 2 2 2 0 HypF Kae1-like domain Glyco_hydro_100 PF12899.7 PVD25658.1 - 0.022 13.4 0.0 0.66 8.6 0.0 2.2 2 0 0 2 2 2 0 Alkaline and neutral invertase DUF3701 PF12482.8 PVD25658.1 - 0.034 14.2 0.1 13 5.9 0.0 3.8 2 1 1 3 3 3 0 Phage integrase protein K_channel_TID PF07941.11 PVD25659.1 - 0.27 11.7 4.2 0.5 10.9 4.2 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PAN_4 PF14295.6 PVD25660.1 - 9.1 6.3 9.6 0.18 11.7 1.0 2.4 2 0 0 2 2 2 0 PAN domain PAN_1 PF00024.26 PVD25661.1 - 0.0042 17.0 8.0 0.011 15.7 1.1 2.6 2 1 0 2 2 2 2 PAN domain UPF0179 PF03684.13 PVD25663.1 - 0.048 13.6 2.2 1 9.3 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0179) LPD39 PF18858.1 PVD25664.1 - 1.4 9.0 14.2 0.5 10.4 0.5 2.3 1 1 0 2 2 2 0 Large polyvalent protein associated domain 39 PAN_4 PF14295.6 PVD25664.1 - 1.8 8.5 7.6 0.079 12.9 0.9 2.2 2 0 0 2 2 2 0 PAN domain AAA_assoc_2 PF16193.5 PVD25666.1 - 0.27 11.6 1.7 1.7 9.0 0.3 2.7 1 1 2 3 3 3 0 AAA C-terminal domain Baculo_LEF-10 PF07206.11 PVD25666.1 - 2.1 8.6 8.0 17 5.7 0.0 3.7 1 1 2 3 3 3 0 Baculovirus late expression factor 10 (LEF-10) Methyltransf_30 PF05430.11 PVD25667.1 - 0.0038 17.1 0.1 44 4.0 0.0 5.1 3 2 4 7 7 7 2 S-adenosyl-L-methionine-dependent methyltransferase TPR_19 PF14559.6 PVD25668.1 - 0.26 11.8 5.6 0.51 10.9 3.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Baculo_LEF-10 PF07206.11 PVD25668.1 - 0.89 9.8 4.8 3.1 8.0 1.0 2.6 1 1 1 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) DMA PF03474.14 PVD25668.1 - 2.9 7.5 4.6 24 4.6 0.1 3.4 3 1 1 4 4 4 0 DMRTA motif DUF2156 PF09924.9 PVD25669.1 - 0.039 12.9 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF4209 PF13910.6 PVD25670.1 - 4.6e-21 74.9 0.0 7.4e-20 71.0 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4209) HSL_N PF06350.12 PVD25670.1 - 0.062 12.3 0.4 0.14 11.1 0.4 1.5 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus 7tm_1 PF00001.21 PVD25672.1 - 4.3e-37 127.9 12.3 6.8e-37 127.2 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD25672.1 - 6.5e-06 26.1 8.1 9.8e-06 25.5 8.1 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD25672.1 - 7.8e-06 25.5 10.1 1.1e-05 24.9 10.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD25672.1 - 1.6e-05 24.7 8.4 2.5e-05 24.1 8.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Clathrin_bdg PF15045.6 PVD25673.1 - 2.3e-11 43.5 0.1 1.4e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Ion_trans_2 PF07885.16 PVD25674.1 - 1e-11 44.6 2.3 7.2e-09 35.5 0.1 2.3 2 0 0 2 2 2 2 Ion channel Peptidase_M4 PF01447.18 PVD25675.1 - 4.6e-23 82.3 0.0 9.5e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 PVD25675.1 - 2.9e-08 33.7 0.0 7.5e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Laminin_G_3 PF13385.6 PVD25675.1 - 0.033 14.3 0.9 0.097 12.8 0.9 1.8 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Sel1 PF08238.12 PVD25676.1 - 4.2e-50 167.0 40.6 2.5e-09 37.5 0.3 12.7 13 0 0 13 13 13 11 Sel1 repeat Flu_M1_C PF08289.11 PVD25676.1 - 0.013 15.7 0.0 0.046 13.9 0.0 2.0 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AcrZ PF10766.9 PVD25676.1 - 0.2 11.3 0.4 0.61 9.7 0.1 1.9 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ AIP3 PF03915.13 PVD25678.1 - 0.02 14.0 1.5 0.021 13.9 1.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 FlaC_arch PF05377.11 PVD25678.1 - 0.085 13.3 0.7 0.17 12.3 0.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CARD_2 PF16739.5 PVD25679.1 - 4.5e-07 29.8 0.0 5.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Caspase recruitment domain CARD PF00619.21 PVD25679.1 - 4.3e-06 26.7 0.1 5.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Caspase recruitment domain DEP PF00610.21 PVD25680.1 - 0.033 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FH2 PF02181.23 PVD25682.1 - 3.3e-68 230.5 0.6 3.3e-68 230.5 0.6 2.8 2 1 1 3 3 3 1 Formin Homology 2 Domain Latarcin PF10279.9 PVD25682.1 - 0.0001 22.6 1.6 3.2 8.2 4.0 3.8 4 1 0 4 4 4 2 Latarcin precursor NT5C PF06941.12 PVD25682.1 - 0.16 11.9 0.7 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DivIC PF04977.15 PVD25682.1 - 0.62 9.9 13.7 0.38 10.6 2.3 3.1 3 0 0 3 3 3 0 Septum formation initiator Vir_act_alpha_C PF10400.9 PVD25682.1 - 1.9 9.2 12.9 13 6.6 1.4 3.8 4 0 0 4 4 4 0 Virulence activator alpha C-term V_ATPase_I PF01496.19 PVD25682.1 - 5 4.9 14.0 0.22 9.4 3.5 2.6 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family PspA_IM30 PF04012.12 PVD25682.1 - 6.1 6.4 19.3 11 5.5 4.6 2.9 2 1 0 2 2 2 0 PspA/IM30 family p450 PF00067.22 PVD25683.1 - 1.4e-135 452.6 0.0 2.5e-70 237.5 0.0 3.8 2 2 1 3 3 3 3 Cytochrome P450 MRP-L27 PF09809.9 PVD25683.1 - 0.045 13.6 0.0 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 p450 PF00067.22 PVD25684.1 - 1.4e-92 310.9 0.0 1.8e-92 310.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD25685.1 - 1.5e-151 505.3 6.4 4.2e-80 269.7 0.9 3.8 2 2 1 4 4 4 3 Cytochrome P450 DUF915 PF06028.11 PVD25685.1 - 0.0081 15.5 0.2 3.5 6.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) RIX1 PF08167.12 PVD25685.1 - 0.044 13.5 0.2 31 4.2 0.0 3.6 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Strep_SA_rep PF06696.11 PVD25685.1 - 2.6 8.1 6.4 4 7.5 0.7 2.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat p450 PF00067.22 PVD25686.1 - 0.001 17.9 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD25687.1 - 3.5e-224 744.7 0.4 1e-85 288.2 0.0 4.1 3 1 1 4 4 4 4 Cytochrome P450 RPA_interact_M PF14767.6 PVD25687.1 - 0.025 15.1 2.7 8.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Replication protein A interacting middle DUF915 PF06028.11 PVD25687.1 - 0.09 12.1 0.5 9.8 5.4 0.0 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) p450 PF00067.22 PVD25688.1 - 1.3e-66 225.3 9.0 2.4e-21 76.0 0.1 4.3 4 1 1 5 5 5 4 Cytochrome P450 MSP1b PF03429.13 PVD25688.1 - 0.009 14.2 0.1 0.74 7.8 0.0 2.1 2 0 0 2 2 2 2 Major surface protein 1B Duffy_binding PF05424.11 PVD25688.1 - 0.053 13.6 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Duffy binding domain COX14 PF14880.6 PVD25688.1 - 0.1 12.5 4.8 10 6.0 0.2 3.3 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Tim17 PF02466.19 PVD25688.1 - 0.13 12.6 0.2 22 5.5 0.0 2.6 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family MazG PF03819.17 PVD25688.1 - 0.15 12.2 0.1 9.9 6.4 0.0 2.7 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain p450 PF00067.22 PVD25689.1 - 3.8e-241 800.7 2.1 1.1e-77 261.8 0.1 4.1 3 1 1 4 4 4 4 Cytochrome P450 FAD_binding_7 PF03441.14 PVD25689.1 - 9.1e-59 198.3 0.2 1.6e-58 197.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PVD25689.1 - 1.1e-31 110.1 0.0 2.6e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Tim17 PF02466.19 PVD25689.1 - 1.8e-05 25.1 3.1 0.13 12.7 0.3 3.4 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family RPA_interact_M PF14767.6 PVD25689.1 - 0.014 15.9 5.5 29 5.3 0.1 3.9 3 0 0 3 3 3 0 Replication protein A interacting middle RecG_N PF17190.4 PVD25689.1 - 0.022 15.5 0.5 56 4.6 0.0 3.6 3 0 0 3 3 3 0 RecG N-terminal helical domain NTase_sub_bind PF08780.11 PVD25689.1 - 0.055 13.4 0.1 76 3.3 0.0 3.5 3 0 0 3 3 3 0 Nucleotidyltransferase substrate binding protein like Aminotran_5 PF00266.19 PVD25691.1 - 8e-11 41.5 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V UPF0020 PF01170.18 PVD25691.1 - 0.098 12.3 0.0 0.58 9.8 0.0 2.1 2 1 1 3 3 3 0 Putative RNA methylase family UPF0020 Pacs-1 PF10254.9 PVD25692.1 - 3.5e-152 507.2 0.0 6.7e-152 506.2 0.0 1.5 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein XAP5 PF04921.14 PVD25693.1 - 8.4e-83 278.0 28.5 1.5e-82 277.2 26.7 2.0 1 1 0 1 1 1 1 XAP5, circadian clock regulator DEC-1_N PF04625.13 PVD25693.1 - 0.5 9.3 3.9 0.75 8.7 3.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ank_2 PF12796.7 PVD25695.1 - 9.4e-18 64.6 0.0 4.7e-08 33.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD25695.1 - 2.7e-10 40.3 0.6 1.7 9.0 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD25695.1 - 7.2e-10 39.2 0.5 0.023 15.3 0.0 5.9 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25695.1 - 2e-09 36.9 0.8 0.12 13.0 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 PVD25695.1 - 2.1e-08 34.2 1.3 0.018 15.5 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat WD40 PF00400.32 PVD25696.1 - 9.4e-23 80.1 16.4 5.7e-07 30.1 0.1 6.8 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25696.1 - 7.2e-09 35.8 0.6 0.0045 17.2 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BTB PF00651.31 PVD25696.1 - 1.2e-08 35.2 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LisH_TPL PF17814.1 PVD25696.1 - 1.4e-05 24.6 0.1 3.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 PVD25696.1 - 0.0027 16.7 0.1 0.032 13.2 0.0 2.3 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4589 PF15252.6 PVD25696.1 - 0.006 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) CLTH PF10607.9 PVD25696.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Pectate_lyase22 PF14583.6 PVD25696.1 - 0.027 13.2 0.1 0.042 12.5 0.1 1.3 1 0 0 1 1 1 0 Oligogalacturonate lyase PD40 PF07676.12 PVD25696.1 - 0.042 13.8 2.0 22 5.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mab-21 PF03281.14 PVD25697.1 - 0.0027 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 PVD25700.1 - 5.3e-38 131.0 0.3 1e-37 130.0 0.3 1.4 1 1 0 1 1 1 1 Mab-21 protein Thyroglobulin_1 PF00086.18 PVD25700.1 - 0.0015 18.2 0.0 0.0015 18.2 0.0 2.8 3 1 0 3 3 3 1 Thyroglobulin type-1 repeat Cystatin PF00031.21 PVD25701.1 - 5.8e-05 23.3 0.1 0.00011 22.3 0.1 1.6 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 PVD25701.1 - 0.0047 17.2 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor p450 PF00067.22 PVD25702.1 - 3.4e-85 286.5 0.1 2e-83 280.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Pox_P4A PF03395.14 PVD25702.1 - 0.011 13.4 0.0 0.015 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein p450 PF00067.22 PVD25703.1 - 4.8e-117 391.5 0.0 6.2e-69 232.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Spore_III_AF PF09581.10 PVD25703.1 - 0.053 13.5 0.3 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) p450 PF00067.22 PVD25704.1 - 5.8e-70 236.3 0.0 6.8e-69 232.8 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.23 PVD25704.1 - 0.041 13.5 0.2 0.041 13.5 0.2 1.6 2 0 0 2 2 2 0 ABC transporter transmembrane region p450 PF00067.22 PVD25705.1 - 1.7e-143 478.7 0.1 2.7e-77 260.5 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 DUF4246 PF14033.6 PVD25705.1 - 0.037 13.1 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) USP7_ICP0_bdg PF12436.8 PVD25705.1 - 0.11 11.8 0.0 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 VCBS PF13517.6 PVD25706.1 - 1.7e-14 54.2 12.4 3.3e-07 30.8 0.8 6.0 4 2 2 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PVD25706.1 - 0.00036 20.6 19.4 0.82 9.9 0.1 6.1 6 0 0 6 6 6 4 FG-GAP repeat Keratin_2_head PF16208.5 PVD25706.1 - 0.0014 18.8 11.2 0.0029 17.8 11.2 1.5 1 0 0 1 1 1 1 Keratin type II head PQQ_2 PF13360.6 PVD25706.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Itfg2 PF15907.5 PVD25706.1 - 0.13 11.2 1.3 3.4 6.6 0.0 3.3 4 0 0 4 4 4 0 Integrin-alpha FG-GAP repeat-containing protein 2 TcdB_toxin_midN PF12256.8 PVD25706.1 - 0.28 10.5 1.9 38 3.6 0.0 3.8 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region TPR_2 PF07719.17 PVD25707.1 - 6.6e-20 69.6 7.7 0.0031 17.5 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD25707.1 - 7.4e-20 69.9 13.0 3.7e-06 26.5 0.2 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 PVD25707.1 - 1e-13 51.4 8.3 2.5e-05 24.5 0.4 5.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD25707.1 - 3.5e-13 48.6 6.2 0.2 12.0 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD25707.1 - 3.2e-10 39.9 4.7 0.029 15.2 0.0 6.1 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD25707.1 - 4e-09 35.9 9.1 0.71 10.0 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD25707.1 - 1.6e-08 34.3 4.1 0.029 14.7 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD25707.1 - 3.7e-08 33.8 4.5 0.05 14.1 0.0 5.0 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD25707.1 - 6.1e-08 32.2 5.6 0.4 10.4 0.2 6.1 5 1 1 6 6 6 3 TPR repeat TPR_6 PF13174.6 PVD25707.1 - 3.7e-07 30.4 7.6 3.8 8.3 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 PVD25707.1 - 9.6e-06 25.0 2.1 0.00011 21.5 1.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD25707.1 - 0.00029 21.4 4.0 1.3 9.7 0.0 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD25707.1 - 0.0047 17.1 13.3 0.25 11.6 1.4 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PVD25707.1 - 0.014 15.5 2.6 6.5 7.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5112 PF17139.4 PVD25707.1 - 0.017 14.6 0.5 4.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5112) FERM_M PF00373.18 PVD25709.1 - 1.8e-40 138.0 0.0 3.7e-40 137.0 0.0 1.6 1 1 0 1 1 1 1 FERM central domain PH PF00169.29 PVD25709.1 - 2.8e-06 27.8 0.7 6.2e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 PH domain Transket_pyr PF02779.24 PVD25710.1 - 6.3e-60 201.9 0.0 1.7e-59 200.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 PVD25710.1 - 2.9e-47 160.2 0.0 4.6e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 PVD25710.1 - 1.2e-42 146.0 0.0 2.4e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component PFOR_II PF17147.4 PVD25710.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF4477 PF14780.6 PVD25711.1 - 0.00014 21.5 0.6 0.00028 20.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) DUF4050 PF13259.6 PVD25711.1 - 0.027 14.8 0.9 0.039 14.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Propeptide_C1 PF08127.13 PVD25711.1 - 0.18 11.8 0.7 0.43 10.5 0.2 1.8 2 0 0 2 2 2 0 Peptidase family C1 propeptide zf-C3HC4_3 PF13920.6 PVD25712.1 - 2.4e-08 33.7 16.8 2.4e-08 33.7 16.8 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD25712.1 - 0.0004 20.2 16.1 0.0004 20.2 16.1 3.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 CLASP_N PF12348.8 PVD25713.1 - 5.6e-30 104.6 9.5 2.4e-12 46.9 0.0 4.4 4 0 0 4 4 4 4 CLASP N terminal HEAT_2 PF13646.6 PVD25713.1 - 1.3e-12 47.9 0.3 0.097 13.1 0.0 7.8 5 3 3 8 8 8 2 HEAT repeats HEAT PF02985.22 PVD25713.1 - 9.7e-12 44.1 6.1 1.6 9.2 0.0 10.2 13 0 0 13 13 10 3 HEAT repeat Cnd1 PF12717.7 PVD25713.1 - 1.8e-08 34.6 13.8 0.0069 16.4 1.2 6.3 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PVD25713.1 - 4.7e-08 33.5 1.4 1.1 9.9 0.2 6.0 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 PVD25713.1 - 7.8e-06 25.2 5.3 0.16 11.1 0.1 4.0 3 1 0 3 3 3 2 Dopey, N-terminal Adaptin_N PF01602.20 PVD25713.1 - 1.5e-05 23.8 15.3 0.016 13.8 0.4 3.8 3 1 0 3 3 3 3 Adaptin N terminal region VHS PF00790.19 PVD25713.1 - 0.00013 21.8 1.7 0.12 12.3 0.2 4.1 3 0 0 3 3 3 1 VHS domain NUC173 PF08161.12 PVD25713.1 - 0.00016 21.4 2.1 0.039 13.6 0.2 3.3 3 0 0 3 3 3 2 NUC173 domain HEAT_EZ PF13513.6 PVD25713.1 - 0.00075 20.0 5.0 0.11 13.1 0.0 6.1 7 0 0 7 7 6 1 HEAT-like repeat RTP1_C1 PF10363.9 PVD25713.1 - 0.003 17.7 7.8 0.23 11.7 0.1 5.8 4 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 PVD25713.1 - 0.06 13.3 11.8 0.34 10.8 0.1 5.3 6 1 0 6 6 6 0 UME (NUC010) domain TAN PF11640.8 PVD25713.1 - 0.07 13.3 1.1 61 3.7 0.0 4.7 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair CDRT4 PF15213.6 PVD25713.1 - 0.22 12.2 4.7 0.69 10.5 4.7 1.8 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Cnd3 PF12719.7 PVD25713.1 - 0.22 10.7 2.0 2.1 7.4 0.1 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.7 PVD25713.1 - 0.26 11.2 6.9 0.43 10.5 1.1 3.7 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CNRIP1 PF15043.6 PVD25714.1 - 7.1e-20 71.1 0.2 4.1e-12 45.9 0.1 2.0 2 0 0 2 2 2 2 CB1 cannabinoid receptor-interacting protein 1 IBR PF01485.21 PVD25716.1 - 3.7e-11 43.1 28.8 1.4e-08 34.8 5.6 4.5 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PVD25716.1 - 0.00045 20.5 2.6 0.00045 20.5 2.6 4.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD25716.1 - 0.00083 19.3 4.1 0.00083 19.3 4.1 3.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD25716.1 - 0.0016 18.3 1.3 0.0016 18.3 1.3 3.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD25716.1 - 0.0016 18.4 2.1 0.0016 18.4 2.1 3.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD25716.1 - 0.0026 17.6 2.0 0.0026 17.6 2.0 5.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD25716.1 - 0.0045 16.8 1.4 0.0045 16.8 1.4 5.1 3 3 2 5 5 5 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 PVD25716.1 - 0.027 14.6 7.5 0.37 10.9 0.7 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 PVD25716.1 - 2.2 8.5 29.4 3.6 7.8 9.9 4.5 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Kunitz_BPTI PF00014.23 PVD25717.1 - 3.4e-25 88.0 10.4 2.3e-17 63.0 6.5 2.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 PVD25719.1 - 1.6e-146 476.5 120.7 7.5e-19 67.7 8.8 8.8 8 0 0 8 8 8 8 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 PVD25719.1 - 1.9e-37 127.2 0.1 7.9e-10 38.7 0.0 4.5 3 1 1 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD25719.1 - 5.8e-36 122.9 9.6 1.8e-10 41.3 0.0 5.8 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 PVD25719.1 - 1.8e-25 89.1 8.2 9.9e-09 35.4 0.1 5.3 4 1 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 PVD25719.1 - 8.7e-18 64.3 0.9 5.3e-05 23.3 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_6 PF18452.1 PVD25719.1 - 1.2e-07 31.2 0.0 0.01 15.4 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD25719.1 - 4.3e-07 29.9 0.4 0.006 16.6 0.1 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD25719.1 - 3.3e-06 27.2 21.7 0.1 12.8 0.1 8.3 7 3 1 8 8 8 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD25719.1 - 2.7e-05 24.1 0.2 4.9 7.3 0.0 4.1 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain SAD_SRA PF02182.17 PVD25719.1 - 1.3 8.7 5.0 39 3.9 0.0 4.5 5 1 0 5 5 5 0 SAD/SRA domain Rad51 PF08423.11 PVD25728.1 - 1.2e-43 149.2 0.0 1.5e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PVD25728.1 - 2.6e-10 40.2 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PVD25728.1 - 7e-09 35.4 1.0 1.1e-07 31.4 1.0 2.2 1 1 0 1 1 1 1 KaiC RecA PF00154.21 PVD25728.1 - 9.1e-08 31.9 0.1 2.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_24 PF13479.6 PVD25728.1 - 2.9e-05 23.9 0.0 4.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PVD25728.1 - 4.1e-05 23.0 0.0 0.00045 19.6 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.6 PVD25728.1 - 0.0051 16.8 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD25728.1 - 0.031 14.6 0.1 0.073 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD25728.1 - 0.058 13.9 0.1 0.092 13.3 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRP54_N PF02881.19 PVD25728.1 - 0.16 12.2 0.6 4.8 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Ank_2 PF12796.7 PVD25729.1 - 2.8e-88 290.6 21.1 6.3e-15 55.5 0.5 14.4 7 2 5 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25729.1 - 2.7e-77 254.2 23.5 2.5e-08 34.3 0.5 18.9 14 5 7 21 21 21 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD25729.1 - 4.6e-55 183.0 23.9 5.7e-05 23.3 0.0 19.4 16 6 6 22 22 22 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25729.1 - 1.3e-52 169.6 31.1 0.0061 17.0 0.2 25.4 27 0 0 27 27 27 12 Ankyrin repeat Ank PF00023.30 PVD25729.1 - 7.7e-49 162.1 28.0 0.017 15.5 0.3 22.8 24 0 0 24 24 24 12 Ankyrin repeat PARP PF00644.20 PVD25729.1 - 1.2e-37 129.4 0.0 3.3e-37 128.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PVD25729.1 - 8.7e-25 87.4 1.5 1.8e-24 86.4 1.5 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PVD25729.1 - 8.1e-22 77.1 0.5 8.1e-22 77.1 0.5 2.2 2 0 0 2 2 2 1 WGR domain BSP_II PF05432.11 PVD25729.1 - 0.0047 16.7 4.4 0.014 15.1 4.4 1.7 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Mqo PF06039.15 PVD25729.1 - 0.097 11.2 0.1 0.46 9.0 0.1 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) EF1G PF00647.19 PVD25730.1 - 5.8e-44 148.5 2.0 1.3e-43 147.4 2.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 PVD25730.1 - 2.5e-16 59.8 0.0 7.9e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD25730.1 - 3.7e-14 52.7 0.0 3.7e-14 52.7 0.0 2.3 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD25730.1 - 7e-06 26.0 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD25730.1 - 1.1e-05 25.6 0.0 1.1e-05 25.6 0.0 2.3 3 0 0 3 3 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD25730.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CCSAP PF15748.5 PVD25730.1 - 0.062 13.5 8.9 0.11 12.7 8.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Mitofilin PF09731.9 PVD25730.1 - 0.18 10.6 9.5 0.25 10.2 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2201_N PF13203.6 PVD25730.1 - 0.21 11.1 3.5 0.33 10.5 3.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NARP1 PF12569.8 PVD25730.1 - 0.39 9.6 8.0 0.6 9.0 8.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 PVD25730.1 - 0.56 10.4 3.8 1 9.5 3.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal U79_P34 PF03064.16 PVD25730.1 - 1.2 8.4 6.5 1.9 7.8 6.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.12 PVD25730.1 - 2.1 8.1 10.0 3.1 7.5 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_1 PF00036.32 PVD25731.1 - 6.2e-27 91.1 16.7 9.7e-07 27.9 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 PVD25731.1 - 7e-25 87.3 4.3 1.2e-13 51.3 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD25731.1 - 1.8e-20 71.1 12.3 1.4e-05 24.6 0.2 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 PVD25731.1 - 4.7e-20 70.1 12.1 5.4e-05 22.5 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 PVD25731.1 - 4.6e-18 64.8 8.8 0.00015 21.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD25731.1 - 5.6e-08 33.1 0.1 0.0014 18.9 0.0 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD25731.1 - 5.5e-07 29.5 6.1 0.0012 18.8 0.4 3.6 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PVD25731.1 - 0.00031 21.0 0.1 0.05 13.9 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 PVD25731.1 - 0.057 13.3 2.5 10 6.0 0.1 3.4 2 2 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 PVD25731.1 - 1.5 9.1 6.9 2.7 8.2 1.4 3.2 1 1 2 3 3 3 0 Dockerin type I domain Lipase3_N PF03893.16 PVD25735.1 - 0.62 10.1 2.0 4 7.5 0.1 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region Ldl_recept_a PF00057.18 PVD25736.1 - 0.029 14.6 17.4 0.029 14.6 17.4 2.1 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Pkinase_Tyr PF07714.17 PVD25737.1 - 1.1e-90 303.5 0.0 1.5e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD25737.1 - 7.1e-38 130.5 0.0 1.2e-37 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD25737.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PWI PF01480.17 PVD25738.1 - 2.7e-14 53.2 0.3 5.7e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 PVD25738.1 - 2e-07 30.7 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 PVD25739.1 - 5.8e-15 55.1 25.9 5.2e-12 45.4 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPPK_C PF12555.8 PVD25739.1 - 0.13 12.3 1.2 0.53 10.4 1.2 2.0 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 PVD25740.1 - 1.2e-06 27.7 27.3 9.3e-05 21.5 8.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 PVD25741.1 - 1.3e-29 103.3 0.0 2.9e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD25741.1 - 1.4e-08 34.4 0.1 3.2e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PVD25741.1 - 1e-05 25.4 0.1 3.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 PVD25741.1 - 9.7e-05 22.2 0.1 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD25741.1 - 0.00087 19.6 0.2 0.059 13.6 0.2 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 PVD25741.1 - 0.0014 17.9 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 PVD25741.1 - 0.0018 18.3 0.0 0.0055 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PVD25741.1 - 0.0022 18.1 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PVD25741.1 - 0.0083 16.5 2.9 0.18 12.2 0.3 3.4 3 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 PVD25741.1 - 0.0086 15.5 0.3 0.042 13.2 0.3 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 PVD25741.1 - 0.011 15.2 0.0 6.2 6.2 0.0 3.3 3 1 1 4 4 4 0 Bacterial TniB protein IstB_IS21 PF01695.17 PVD25741.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MIT PF04212.18 PVD25741.1 - 0.018 15.1 1.8 0.055 13.5 1.8 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_14 PF13173.6 PVD25741.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP-bdg_M PF16360.5 PVD25741.1 - 0.07 13.7 0.9 1.1 9.9 0.1 2.9 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region RHD_DNA_bind PF00554.22 PVD25742.1 - 1.4e-08 34.9 0.1 4.2e-08 33.3 0.1 1.9 1 1 1 2 2 2 1 Rel homology DNA-binding domain DEAD PF00270.29 PVD25743.1 - 5.1e-36 124.1 0.0 9.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD25743.1 - 1.2e-27 96.5 0.1 8.4e-27 93.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD25743.1 - 0.00086 19.4 0.0 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD25743.1 - 0.0076 16.6 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD25743.1 - 0.024 14.9 0.5 0.25 11.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PVD25743.1 - 0.035 13.5 0.0 0.36 10.2 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein MgtE_N PF03448.17 PVD25743.1 - 0.12 13.0 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Helicase_RecD PF05127.14 PVD25743.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase FIBP PF05427.11 PVD25744.1 - 8.4e-116 387.2 1.6 1e-115 386.9 1.6 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) CNH PF00780.22 PVD25745.1 - 8.8e-55 186.2 0.4 1.7e-54 185.3 0.4 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 PVD25745.1 - 2.6e-54 184.4 0.0 8.7e-54 182.6 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25745.1 - 4.6e-29 101.5 0.0 1.1e-28 100.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase KELK PF15796.5 PVD25745.1 - 6.1e-16 58.6 18.1 6.1e-16 58.6 18.1 5.8 3 2 1 5 5 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase C1_1 PF00130.22 PVD25745.1 - 2.2e-09 37.1 10.8 4.6e-09 36.0 10.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DMPK_coil PF08826.10 PVD25745.1 - 5e-07 29.7 11.5 5e-07 29.7 11.5 6.9 4 3 2 6 6 5 1 DMPK coiled coil domain like PH PF00169.29 PVD25745.1 - 2.2e-06 28.1 0.7 2.6e-05 24.7 0.0 2.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 PVD25745.1 - 4.3e-06 26.3 0.0 4.3e-06 26.3 0.0 2.6 3 0 0 3 3 2 1 Kinase-like Pkinase_C PF00433.24 PVD25745.1 - 2.2e-05 25.1 1.2 8.9e-05 23.1 1.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF4201 PF13870.6 PVD25745.1 - 3.5e-05 23.6 6.2 3.5e-05 23.6 6.2 4.7 2 1 1 4 4 4 1 Domain of unknown function (DUF4201) PBD PF00786.28 PVD25745.1 - 0.00042 20.6 0.0 0.0018 18.6 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain ZapB PF06005.12 PVD25745.1 - 0.00076 19.9 6.9 0.00076 19.9 6.9 7.8 1 1 7 8 8 7 1 Cell division protein ZapB DUF2205 PF10224.9 PVD25745.1 - 0.0008 19.4 6.9 0.0008 19.4 6.9 5.0 5 2 2 7 7 7 1 Short coiled-coil protein APH PF01636.23 PVD25745.1 - 0.56 10.1 5.6 0.32 10.9 0.2 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1192 PF06698.11 PVD25745.1 - 1 9.5 11.6 19 5.4 1.5 4.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PHD PF00628.29 PVD25745.1 - 4.7 7.2 10.9 12 5.9 10.9 1.7 1 0 0 1 1 1 0 PHD-finger Str_synth PF03088.16 PVD25746.1 - 3.9e-27 94.2 0.0 2.1e-26 91.9 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 PVD25746.1 - 8.6e-17 61.5 0.0 1.7e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 PVD25746.1 - 0.00016 22.1 0.1 0.06 13.9 0.0 3.6 3 1 0 3 3 3 1 PQQ-like domain Arylesterase PF01731.20 PVD25746.1 - 0.00021 21.4 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 PVD25747.1 - 2.2e-19 69.4 0.0 9.1e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 PVD25747.1 - 4.9e-10 39.4 0.0 8.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FliH PF02108.16 PVD25747.1 - 0.0078 16.3 2.6 0.014 15.5 2.6 1.3 1 0 0 1 1 1 1 Flagellar assembly protein FliH NHL PF01436.21 PVD25747.1 - 0.018 15.0 0.0 9.9 6.4 0.0 3.3 2 0 0 2 2 2 0 NHL repeat Arylesterase PF01731.20 PVD25747.1 - 0.034 14.4 0.0 0.092 13.0 0.0 1.8 1 1 0 1 1 1 0 Arylesterase BTB PF00651.31 PVD25748.1 - 4.1e-24 85.0 0.2 4.6e-23 81.6 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD25748.1 - 2.4e-18 66.1 0.1 6.8e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 PVD25748.1 - 6.7e-16 58.6 0.1 5.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain Pkinase PF00069.25 PVD25749.1 - 9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25749.1 - 7.5e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD25749.1 - 0.043 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MNNL PF07657.13 PVD25750.1 - 1.6e-29 101.8 3.3 2e-29 101.4 3.3 1.1 1 0 0 1 1 1 1 N terminus of Notch ligand PRKCSH-like PF12999.7 PVD25750.1 - 0.00063 19.6 0.8 0.00081 19.2 0.8 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like EGF PF00008.27 PVD25751.1 - 9.2e-96 313.6 261.2 5.1e-11 42.7 4.8 18.3 18 0 0 18 18 18 14 EGF-like domain hEGF PF12661.7 PVD25751.1 - 2.9e-59 195.8 220.2 1.4e-07 31.8 7.0 19.4 19 0 0 19 19 19 14 Human growth factor-like EGF EGF_2 PF07974.13 PVD25751.1 - 2.8e-25 88.4 302.8 0.00023 21.5 11.6 19.5 19 0 0 19 19 19 15 EGF-like domain DSL PF01414.19 PVD25751.1 - 1.2e-22 80.0 4.3 1.2e-22 80.0 4.3 14.6 11 4 4 15 15 15 4 Delta serrate ligand EGF_CA PF07645.15 PVD25751.1 - 2.1e-20 72.6 255.9 0.0001 22.4 6.1 18.2 11 4 8 19 19 19 13 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD25751.1 - 0.043 14.1 228.1 0.034 14.4 2.3 18.3 8 3 9 17 17 17 0 Coagulation Factor Xa inhibitory site Arv1 PF04161.13 PVD25752.1 - 6.9e-43 147.3 5.4 8.5e-43 147.0 5.4 1.1 1 0 0 1 1 1 1 Arv1-like family Rpp20 PF12328.8 PVD25753.1 - 6.3e-18 65.1 0.1 1.5e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 PVD25753.1 - 1.3e-12 47.3 0.1 2e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Alba Dpy-30 PF05186.13 PVD25754.1 - 5.2e-21 74.1 0.1 6.2e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 PVD25754.1 - 0.0093 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PNP_UDP_1 PF01048.20 PVD25755.1 - 2.5e-51 174.2 0.0 3.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Seipin PF06775.14 PVD25756.1 - 1.6e-35 123.0 0.1 2.6e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MT-A70 PF05063.14 PVD25756.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 MT-A70 PAP_central PF04928.17 PVD25757.1 - 2.1e-113 377.4 0.0 2.9e-113 376.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PVD25757.1 - 1e-26 93.6 2.7 1.6e-18 67.0 0.2 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PVD25757.1 - 1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 PVD25757.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Tmemb_9 PF05434.11 PVD25757.1 - 0.15 12.0 0.5 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 TMEM9 Globin PF00042.22 PVD25758.1 - 1e-12 48.5 0.1 1.6e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Globin Bcl-2_BAD PF10514.9 PVD25759.1 - 5.4e-05 23.7 3.9 0.0001 22.8 3.9 1.4 1 0 0 1 1 1 1 Pro-apoptotic Bcl-2 protein, BAD Bclx_interact PF08945.10 PVD25759.1 - 0.047 13.5 1.3 0.18 11.6 1.3 2.1 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain FAM60A PF15396.6 PVD25759.1 - 3.5 7.6 7.7 1.9 8.4 2.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A LRR_6 PF13516.6 PVD25760.1 - 2.5e-08 33.3 20.7 0.097 12.8 0.3 6.3 6 0 0 6 6 6 4 Leucine Rich repeat EF-hand_7 PF13499.6 PVD25760.1 - 0.0004 20.8 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD25760.1 - 0.047 13.2 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 EF hand Antigen_Bd37 PF11641.8 PVD25760.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein MCM3AP_GANP PF16769.5 PVD25760.1 - 0.14 10.4 0.5 0.23 9.6 0.5 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP LRR_1 PF00560.33 PVD25760.1 - 0.24 12.1 8.5 38 5.4 0.3 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 PVD25760.1 - 0.96 10.0 3.0 9.5 6.8 0.2 3.1 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) zf-C3HC4 PF00097.25 PVD25761.1 - 4.3e-08 32.9 6.7 4.3e-08 32.9 6.7 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD25761.1 - 3.4e-07 30.2 6.7 3.4e-07 30.2 6.7 3.1 3 1 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD25761.1 - 6.3e-06 26.2 18.0 3.2e-05 24.0 5.2 3.5 4 0 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD25761.1 - 8.5e-06 26.0 7.6 8.5e-06 26.0 7.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD25761.1 - 5.9e-05 22.8 5.2 5.9e-05 22.8 5.2 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD25761.1 - 7.1e-05 22.9 8.6 7.1e-05 22.9 8.6 3.6 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD25761.1 - 0.00013 21.7 8.1 0.00013 21.7 8.1 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD25761.1 - 0.00032 20.5 5.5 0.00032 20.5 5.5 3.6 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 NHL PF01436.21 PVD25761.1 - 0.00049 20.0 0.0 2 8.6 0.0 3.8 3 0 0 3 3 3 1 NHL repeat zf-RING_5 PF14634.6 PVD25761.1 - 0.0017 18.3 6.3 0.0017 18.3 6.3 3.6 3 0 0 3 3 3 1 zinc-RING finger domain Pol_alpha_B_N PF08418.10 PVD25761.1 - 0.012 15.7 1.2 0.017 15.1 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PhoU_div PF01865.16 PVD25761.1 - 0.017 14.4 0.3 0.052 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF47 CEBP_ZZ PF16366.5 PVD25761.1 - 0.22 11.8 24.1 0.36 11.1 5.9 3.5 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1244 PF06844.11 PVD25761.1 - 0.33 11.1 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) DASH_Dad2 PF08654.10 PVD25761.1 - 0.7 10.3 5.1 2.4 8.6 0.2 2.4 1 1 0 2 2 2 0 DASH complex subunit Dad2 Eapp_C PF10238.9 PVD25761.1 - 1.1 9.3 16.1 0.96 9.5 4.1 3.5 2 1 0 3 3 3 0 E2F-associated phosphoprotein TMEM52 PF14979.6 PVD25762.1 - 0.2 11.6 5.9 1.3 8.9 0.6 3.2 2 1 1 3 3 3 0 Transmembrane 52 LELP1 PF15042.6 PVD25764.1 - 2.2 8.7 9.7 2.3 8.7 7.4 2.1 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Ocnus PF05005.15 PVD25765.1 - 4.4e-37 126.5 0.1 5.2e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) TPR_12 PF13424.6 PVD25766.1 - 4.8e-27 94.0 1.6 1.8e-10 40.9 0.0 5.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 PVD25766.1 - 7.8e-18 63.7 2.4 5.4e-05 22.9 1.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD25766.1 - 3.9e-15 54.9 18.5 0.0032 17.2 2.3 7.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD25766.1 - 6.8e-10 38.3 16.9 0.14 12.4 1.5 8.2 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD25766.1 - 1.1e-08 34.5 6.8 0.075 13.1 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF4062 PF13271.6 PVD25766.1 - 4.9e-08 33.2 0.0 1.7e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_MalT PF17874.1 PVD25766.1 - 1.1e-07 31.6 0.1 1.9e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region NACHT PF05729.12 PVD25766.1 - 1.9e-06 27.9 0.0 0.098 12.6 0.0 3.0 3 0 0 3 3 3 2 NACHT domain ATPase_2 PF01637.18 PVD25766.1 - 8.2e-05 22.6 1.0 0.056 13.3 0.0 3.6 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea TPR_16 PF13432.6 PVD25766.1 - 0.00029 21.4 0.0 7.3 7.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 PVD25766.1 - 0.002 18.7 0.0 0.0093 16.5 0.0 2.3 2 0 0 2 2 1 1 ABC transporter TPR_8 PF13181.6 PVD25766.1 - 0.0025 17.9 13.9 0.82 10.0 1.3 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD25766.1 - 0.0046 17.4 3.9 8.8 6.9 0.0 4.5 4 2 1 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 PVD25766.1 - 0.0049 17.3 0.0 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Adeno_IVa2 PF02456.15 PVD25766.1 - 0.0054 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 PVD25766.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 PVD25766.1 - 0.015 14.8 0.0 0.045 13.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD25766.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Lgl_C PF08596.10 PVD25766.1 - 0.018 13.8 0.1 0.036 12.8 0.1 1.4 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal TPR_17 PF13431.6 PVD25766.1 - 0.044 14.2 2.9 29 5.3 0.9 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat AAA PF00004.29 PVD25766.1 - 0.051 14.0 0.1 14 6.1 0.0 3.3 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD25766.1 - 0.054 13.8 0.0 1.4 9.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Pup PF05639.11 PVD25766.1 - 0.13 13.2 0.4 0.89 10.5 0.0 2.5 2 0 0 2 2 1 0 Pup-like protein PhoH PF02562.16 PVD25766.1 - 0.13 11.7 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RPN7 PF10602.9 PVD25766.1 - 0.15 11.8 5.5 2.4 7.8 0.0 3.2 2 1 1 3 3 2 0 26S proteasome subunit RPN7 DUF2225 PF09986.9 PVD25766.1 - 1.1 8.9 7.3 0.73 9.5 4.2 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) EF-hand_5 PF13202.6 PVD25767.1 - 4.9e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PVD25767.1 - 0.00037 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 PVD25767.1 - 0.0031 16.9 0.0 0.009 15.5 0.0 1.8 1 0 0 1 1 1 1 EF hand Cupin_7 PF12973.7 PVD25767.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 ChrR Cupin-like domain EF-hand_7 PF13499.6 PVD25767.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair ASC PF00858.24 PVD25768.1 - 2e-86 290.7 1.0 1.6e-65 221.9 0.2 2.1 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel DUF4175 PF13779.6 PVD25768.1 - 2.3 6.0 5.8 3.3 5.5 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Metallophos_2 PF12850.7 PVD25769.1 - 0.022 14.9 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PVD25769.1 - 0.051 14.1 0.0 0.058 13.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Pinin_SDK_N PF04697.13 PVD25770.1 - 4.7e-39 134.2 3.6 4.7e-39 134.2 3.6 3.6 3 1 0 4 4 4 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.13 PVD25770.1 - 7e-29 100.5 18.1 7e-29 100.5 18.1 4.1 3 1 1 4 4 4 1 pinin/SDK/memA/ protein conserved region GAPES1 PF17155.4 PVD25770.1 - 0.16 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain FtsJ PF01728.19 PVD25771.1 - 1.2e-26 93.9 0.0 5.7e-25 88.4 0.0 2.4 1 1 1 2 2 2 1 FtsJ-like methyltransferase G-patch PF01585.23 PVD25771.1 - 4e-15 55.4 5.8 7.3e-15 54.6 5.8 1.5 1 0 0 1 1 1 1 G-patch domain mRNA_cap_enzyme PF01331.19 PVD25771.1 - 0.00023 21.1 0.2 0.00046 20.1 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain G-patch_2 PF12656.7 PVD25771.1 - 0.00032 20.7 3.4 0.0007 19.6 3.4 1.6 1 0 0 1 1 1 1 G-patch domain 7tm_1 PF00001.21 PVD25772.1 - 1.2e-26 93.7 12.9 1.5e-26 93.3 12.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM132D_C PF15706.5 PVD25772.1 - 1.6 8.6 4.6 9.4 6.1 0.2 2.9 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 PVD25773.1 - 0.0088 16.9 0.3 0.022 15.6 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 PVD25773.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CbtA PF09490.10 PVD25773.1 - 0.054 13.3 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TMEM154 PF15102.6 PVD25773.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Zip PF02535.22 PVD25773.1 - 0.19 10.9 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter OB_NTP_bind PF07717.16 PVD25775.1 - 2.1e-21 76.1 0.0 5.4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PVD25775.1 - 5e-19 68.6 0.0 2e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PVD25775.1 - 9.5e-15 54.9 0.0 2.3e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD25775.1 - 7.8e-12 45.3 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 PVD25775.1 - 1.2e-07 32.0 0.0 8.6e-07 29.3 0.0 2.5 1 1 0 1 1 1 1 RWD domain zf-CCCH_4 PF18044.1 PVD25775.1 - 3e-05 23.7 4.5 6.3e-05 22.7 4.5 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD25775.1 - 0.00013 21.9 8.6 0.00025 21.0 8.6 1.5 1 0 0 1 1 1 1 Zinc finger domain UBA PF00627.31 PVD25775.1 - 0.00036 20.4 3.4 0.0054 16.6 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain zf-CCCH PF00642.24 PVD25775.1 - 0.0012 18.7 4.5 0.0037 17.2 4.5 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PVD25775.1 - 0.0031 18.2 0.2 0.013 16.2 0.2 2.0 1 0 0 1 1 1 1 Torus domain AAA_19 PF13245.6 PVD25775.1 - 0.0032 17.8 0.0 0.0075 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PVD25775.1 - 0.01 15.9 0.1 0.091 12.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 PVD25775.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 PVD25775.1 - 0.038 13.0 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 PVD25775.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 PVD25775.1 - 0.1 12.9 0.9 0.65 10.3 0.9 2.3 1 1 0 1 1 1 0 AAA domain Adap_comp_sub PF00928.21 PVD25776.1 - 1.2e-17 64.2 0.0 2.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Radial_spoke PF04712.12 PVD25776.1 - 4.1e-11 42.5 0.5 8.3e-09 34.9 0.4 2.9 1 1 2 3 3 3 3 Radial spokehead-like protein SKA2 PF16740.5 PVD25779.1 - 0.094 12.5 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FUSC-like PF12805.7 PVD25779.1 - 0.19 10.8 0.9 0.3 10.1 0.9 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Patched PF02460.18 PVD25783.1 - 2.2e-21 75.7 24.7 1.6e-11 43.1 11.6 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 PVD25783.1 - 6.7e-14 52.0 25.5 4.4e-10 39.6 9.5 2.3 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 PVD25783.1 - 1.5e-05 24.1 13.7 0.0013 17.7 2.0 2.5 2 1 0 2 2 2 2 MMPL family 7tm_1 PF00001.21 PVD25786.1 - 1.7e-13 50.5 1.0 1.7e-13 50.5 1.0 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Claudin_2 PF13903.6 PVD25786.1 - 0.0059 16.4 0.1 0.0066 16.2 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF5056 PF16479.5 PVD25786.1 - 0.36 11.1 2.6 0.53 10.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) CAP_N PF01213.19 PVD25787.1 - 0.28 10.6 7.3 0.048 13.2 3.3 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TFIIB PF00382.19 PVD25788.1 - 2.1e-28 98.1 0.2 2.5e-15 56.3 0.1 3.0 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 PVD25788.1 - 9.1e-26 90.1 16.4 9.1e-26 90.1 16.4 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 PVD25788.1 - 6.1e-11 41.7 3.4 1.5e-10 40.4 3.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 PVD25788.1 - 5e-07 29.5 0.4 0.00062 19.5 0.1 2.8 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 PVD25788.1 - 0.082 12.9 0.3 0.082 12.9 0.3 2.3 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 PVD25788.1 - 2.7 7.5 6.5 61 3.2 6.5 2.4 1 1 0 1 1 1 0 zinc-ribbon domain ABC_membrane PF00664.23 PVD25789.1 - 2.6e-66 224.1 6.4 3.6e-66 223.6 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD25789.1 - 1.2e-33 116.5 0.0 2.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD25789.1 - 2.2e-06 27.3 0.2 0.014 14.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PVD25789.1 - 0.0016 18.2 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD25789.1 - 0.0052 16.6 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PVD25789.1 - 0.0076 16.5 0.3 0.044 14.0 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD25789.1 - 0.012 16.0 0.1 0.043 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 PVD25789.1 - 0.031 14.0 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PVD25789.1 - 0.043 13.9 1.4 0.048 13.8 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3987 PF13148.6 PVD25789.1 - 0.044 12.8 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 PVD25789.1 - 0.084 13.4 0.1 0.38 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Yip1 PF04893.17 PVD25789.1 - 0.5 10.1 7.3 1.5 8.5 7.1 1.9 1 1 0 1 1 1 0 Yip1 domain DUF89 PF01937.19 PVD25791.1 - 1.3e-113 379.6 0.0 1.5e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acetyltransf_1 PF00583.25 PVD25792.1 - 0.0039 17.4 0.1 0.0063 16.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD25792.1 - 0.037 14.5 0.3 0.052 14.0 0.3 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD25792.1 - 0.037 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRIMA1 PF16101.5 PVD25792.1 - 0.046 13.8 11.9 0.065 13.3 11.9 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD25792.1 - 0.093 12.2 10.7 0.12 11.8 10.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MSA-2c PF12238.8 PVD25792.1 - 0.13 12.2 1.7 0.15 12.1 1.7 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Mito_fiss_reg PF05308.11 PVD25792.1 - 0.14 12.3 8.5 0.17 11.9 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PAP_PilO PF06864.12 PVD25792.1 - 0.59 8.9 1.8 0.7 8.7 1.8 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Ald_Xan_dh_C2 PF02738.18 PVD25793.1 - 3.6e-149 497.7 0.0 3.8e-112 375.5 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PVD25793.1 - 3e-31 108.0 0.8 5.9e-31 107.1 0.8 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 PVD25793.1 - 3.3e-30 104.3 0.0 1.1e-29 102.6 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 PVD25793.1 - 8e-30 103.8 0.0 1.7e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 PVD25793.1 - 7.7e-28 96.3 0.1 1.6e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C2 PF02738.18 PVD25794.1 - 3.7e-190 633.0 0.0 6.2e-190 632.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PVD25794.1 - 1.3e-47 161.7 0.0 2.9e-47 160.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD25794.1 - 8e-31 106.3 0.0 4.2e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 PVD25794.1 - 1.3e-29 102.8 0.7 2.7e-29 101.7 0.7 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD25794.1 - 1.3e-28 98.8 0.1 2.9e-28 97.7 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CBM9_1 PF06452.11 PVD25795.1 - 2e-06 27.8 3.5 4e-06 26.9 3.5 1.5 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 PVD25795.1 - 0.0018 18.0 0.7 0.0018 18.0 0.7 1.8 2 1 0 2 2 2 1 Carbohydrate-binding family 9 CBM9_1 PF06452.11 PVD25796.1 - 5.7e-07 29.6 0.8 1.2e-06 28.6 0.8 1.6 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like LRR_8 PF13855.6 PVD25797.1 - 3.4e-44 148.4 34.8 2.7e-11 43.0 0.1 6.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PVD25797.1 - 2.2e-21 75.6 30.3 8.7e-06 26.0 1.6 7.6 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD25797.1 - 8.9e-12 43.8 31.8 1.9 9.3 0.1 12.0 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_5 PF13306.6 PVD25797.1 - 4.8e-10 39.5 0.0 0.0053 16.7 0.0 4.1 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PVD25797.1 - 1.5e-09 37.1 36.9 0.11 12.7 0.9 10.6 10 1 1 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.6 PVD25797.1 - 1.6e-05 24.5 6.8 0.0096 15.4 0.3 3.3 2 2 2 4 4 4 3 Leucine-rich repeat fn3 PF00041.21 PVD25797.1 - 0.00013 22.2 0.0 0.00058 20.2 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain LRRNT PF01462.18 PVD25797.1 - 0.00053 19.6 0.3 0.00053 19.6 0.3 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain DUF3557 PF12078.8 PVD25797.1 - 0.061 13.3 2.1 1.1 9.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) PhyH PF05721.13 PVD25798.1 - 6.3e-21 75.6 0.0 1.1e-20 74.8 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF746 PF05344.11 PVD25799.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Cys_knot PF00007.22 PVD25803.1 - 2e-05 24.8 0.3 2e-05 24.8 0.3 1.6 2 0 0 2 2 2 1 Cystine-knot domain Opiods_neuropep PF01160.18 PVD25803.1 - 1.8 8.7 7.2 8.8 6.5 4.5 3.1 2 1 1 3 3 3 0 Vertebrate endogenous opioids neuropeptide DAN PF03045.15 PVD25804.1 - 6.3e-06 26.2 2.9 8.2e-06 25.8 2.9 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 PVD25804.1 - 0.00014 22.1 6.7 0.0002 21.6 6.7 1.2 1 0 0 1 1 1 1 Cystine-knot domain Hormone_6 PF00236.18 PVD25804.1 - 0.0036 17.2 5.1 0.005 16.8 5.1 1.3 1 0 0 1 1 1 1 Glycoprotein hormone Baculo_PEP_C PF04513.12 PVD25805.1 - 0.046 13.7 8.6 0.14 12.2 8.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_HK97_TLTM PF06120.11 PVD25805.1 - 0.16 11.1 9.0 0.14 11.4 4.9 2.1 1 1 1 2 2 2 0 Tail length tape measure protein FapA PF03961.13 PVD25805.1 - 0.22 10.1 10.4 0.22 10.1 9.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Rx_N PF18052.1 PVD25805.1 - 0.75 10.1 8.6 1.1 9.6 1.2 2.7 1 1 2 3 3 3 0 Rx N-terminal domain DUF4407 PF14362.6 PVD25805.1 - 1.7 7.9 10.0 5.8 6.2 10.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 PVD25805.1 - 1.9 8.5 25.4 0.053 13.6 16.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 PVD25805.1 - 4.5 7.3 21.5 0.096 12.8 13.8 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RP-C_C PF11800.8 PVD25805.1 - 6.9 6.7 12.1 21 5.1 11.6 2.1 1 1 0 1 1 1 0 Replication protein C C-terminal region Sterol-sensing PF12349.8 PVD25806.1 - 2.2e-15 56.8 30.5 3.8e-14 52.8 17.8 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 PVD25806.1 - 5.3e-13 48.0 30.6 1.4e-11 43.3 15.9 2.3 2 1 0 2 2 2 2 Patched family MMPL PF03176.15 PVD25806.1 - 0.0013 17.7 26.4 0.066 12.1 11.9 2.2 2 0 0 2 2 2 2 MMPL family Pox_I5 PF04713.12 PVD25806.1 - 0.63 10.1 6.8 0.21 11.7 1.3 3.2 3 0 0 3 3 3 0 Poxvirus protein I5 PARP_reg PF02877.14 PVD25807.1 - 4e-49 166.2 0.5 9.1e-49 165.1 0.5 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 PVD25807.1 - 3.5e-40 137.7 0.4 1.6e-38 132.3 0.0 2.6 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-PARP PF00645.18 PVD25807.1 - 3.4e-39 133.6 6.6 7.5e-20 71.6 0.7 3.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 PVD25807.1 - 4e-23 80.9 1.2 4e-23 80.9 1.2 2.1 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.15 PVD25807.1 - 2.3e-22 78.8 0.4 8.4e-22 77.0 0.4 2.1 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 PVD25807.1 - 0.012 16.0 0.2 0.072 13.5 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain CTNNBL PF08216.11 PVD25807.1 - 6.2 7.0 6.3 22 5.3 0.1 3.0 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear YIF1 PF03878.15 PVD25808.1 - 1.1e-74 251.0 6.1 1.3e-74 250.7 6.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 PVD25808.1 - 0.018 14.8 7.1 0.039 13.7 7.1 1.6 1 0 0 1 1 1 0 Yip1 domain WH1 PF00568.23 PVD25809.1 - 3.7e-31 107.3 0.1 5.3e-31 106.8 0.1 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 PVD25809.1 - 3.4e-16 58.5 2.5 5e-16 58.0 2.5 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.18 PVD25809.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 RanBP1 domain FMN_dh PF01070.18 PVD25810.1 - 1.1e-123 412.7 0.0 1.3e-123 412.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 PVD25810.1 - 1.8e-07 30.5 0.3 6.7e-07 28.6 0.2 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 PVD25810.1 - 2e-06 27.2 0.1 0.0011 18.2 0.0 2.6 2 1 1 3 3 3 2 Conserved region in glutamate synthase DHO_dh PF01180.21 PVD25810.1 - 0.00014 21.2 0.2 0.014 14.6 0.0 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.17 PVD25810.1 - 0.0003 20.0 0.2 0.045 12.8 0.1 2.9 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 PVD25810.1 - 0.0012 18.3 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 PVD25810.1 - 0.014 14.9 0.1 0.13 11.7 0.0 2.3 2 1 1 3 3 3 0 Histidine biosynthesis protein DUF3926 PF13080.6 PVD25810.1 - 0.017 15.0 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) NMO PF03060.15 PVD25810.1 - 0.17 11.3 2.3 4.5 6.6 0.3 2.2 1 1 1 2 2 2 0 Nitronate monooxygenase FAM177 PF14774.6 PVD25811.1 - 8.5e-39 132.5 0.4 1.2e-38 132.0 0.4 1.2 1 0 0 1 1 1 1 FAM177 family ZapB PF06005.12 PVD25811.1 - 0.015 15.7 0.2 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB ELM2 PF01448.24 PVD25811.1 - 0.069 13.9 2.8 0.17 12.6 0.2 2.2 2 0 0 2 2 2 0 ELM2 domain Phostensin_N PF13916.6 PVD25811.1 - 0.077 13.3 0.3 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Metallophos PF00149.28 PVD25812.1 - 1.4e-07 32.2 2.0 1.4e-07 32.2 2.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Presenilin PF01080.17 PVD25813.1 - 4.5e-119 397.8 0.0 4.5e-119 397.8 0.0 1.7 2 0 0 2 2 2 1 Presenilin GDA1_CD39 PF01150.17 PVD25814.1 - 1.2e-71 241.6 0.0 1.7e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 PVD25814.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ZFYVE21_C PF16696.5 PVD25815.1 - 7.4e-15 54.9 0.2 7.4e-15 54.9 0.2 1.4 2 0 0 2 2 2 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 PVD25815.1 - 1.2e-12 47.8 21.7 2e-12 47.0 21.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger RecR PF02132.15 PVD25815.1 - 0.27 10.8 0.2 0.27 10.8 0.2 3.9 3 1 0 3 3 3 0 RecR protein Kelch_4 PF13418.6 PVD25816.1 - 1.2e-15 57.2 17.5 6.9e-05 22.8 0.0 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD25816.1 - 5.7e-14 51.8 11.3 0.0047 17.2 0.8 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PVD25816.1 - 4.7e-13 49.1 12.7 0.0035 17.6 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD25816.1 - 2.3e-08 33.5 14.7 6.8e-05 22.4 0.0 5.8 5 2 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 PVD25816.1 - 1e-07 31.8 3.2 0.077 13.0 0.3 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 PVD25816.1 - 0.00062 19.6 10.3 0.013 15.4 0.0 5.1 5 2 0 5 5 5 2 Kelch motif CNRIP1 PF15043.6 PVD25817.1 - 1.7e-34 118.7 0.0 1.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 EGF PF00008.27 PVD25818.1 - 3.9e-119 388.3 353.7 3.5e-07 30.4 3.7 23.1 24 0 0 24 24 24 22 EGF-like domain hEGF PF12661.7 PVD25818.1 - 1.1e-50 168.6 322.2 6.9e-05 23.3 8.8 25.1 26 0 0 26 26 26 21 Human growth factor-like EGF EGF_CA PF07645.15 PVD25818.1 - 2.3e-41 139.7 311.2 0.0001 22.4 3.4 23.2 17 4 6 23 23 23 16 Calcium-binding EGF domain EGF_2 PF07974.13 PVD25818.1 - 3.8e-25 88.0 386.1 0.0042 17.4 7.0 24.1 24 0 0 24 24 24 20 EGF-like domain cEGF PF12662.7 PVD25818.1 - 1.3e-09 37.8 241.1 0.00065 19.6 3.4 25.6 23 3 0 23 23 23 13 Complement Clr-like EGF-like DSL PF01414.19 PVD25818.1 - 8.7e-08 32.3 7.0 8.7e-08 32.3 7.0 15.3 11 5 6 17 17 17 1 Delta serrate ligand SP_C-Propep PF08999.10 PVD25818.1 - 0.014 15.1 0.2 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EGF_3 PF12947.7 PVD25818.1 - 0.017 15.3 3.2 0.017 15.3 3.2 23.6 20 3 3 23 23 23 0 EGF domain Peptidase_S9 PF00326.21 PVD25820.1 - 4e-42 144.1 0.0 6.9e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PVD25820.1 - 5.8e-07 29.4 0.0 0.013 15.1 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 PVD25820.1 - 1.8e-06 27.4 0.1 0.026 13.8 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD25820.1 - 3e-05 23.8 0.2 0.23 11.1 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 PVD25820.1 - 5.2e-05 22.9 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 PVD25820.1 - 0.0012 18.7 0.1 0.79 9.7 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF5050 PF16472.5 PVD25820.1 - 0.0028 16.9 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) AXE1 PF05448.12 PVD25820.1 - 0.0043 15.8 0.2 0.069 11.8 0.0 2.4 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 PVD25820.1 - 0.0097 15.4 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 PVD25820.1 - 0.02 14.8 0.0 4.6 7.1 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 PVD25820.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD25821.1 - 9.2e-15 54.5 0.1 5.6e-12 45.4 0.0 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD25821.1 - 3.6e-08 34.3 0.9 1.4e-07 32.4 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD25821.1 - 4e-08 33.2 0.6 4.5e-07 29.8 0.6 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Vps16_C PF04840.12 PVD25821.1 - 1.5e-07 30.8 1.3 0.0058 15.7 0.1 2.3 2 0 0 2 2 2 2 Vps16, C-terminal region Peptidase_S9 PF00326.21 PVD25821.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family IL2 PF00715.17 PVD25821.1 - 0.053 13.5 1.3 0.072 13.0 0.1 1.8 2 0 0 2 2 2 0 Interleukin 2 PEP-utilisers_N PF05524.13 PVD25821.1 - 0.24 11.6 1.1 7.5 6.8 0.0 3.0 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Sld5 PF05916.11 PVD25822.1 - 0.00013 22.3 0.1 0.00029 21.3 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein Kinesin PF00225.23 PVD25824.1 - 1.5e-86 290.4 0.0 1.5e-86 290.4 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD25824.1 - 7.3e-12 45.5 0.0 7.3e-12 45.5 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 PVD25824.1 - 8.7e-05 22.7 0.5 0.0058 16.8 0.0 6.6 7 1 1 8 8 8 2 Kinesin-associated FHA PF00498.26 PVD25824.1 - 0.00013 22.3 0.1 0.00013 22.3 0.1 3.4 4 0 0 4 4 4 1 FHA domain Yop-YscD_cpl PF16697.5 PVD25824.1 - 0.00077 19.7 0.0 0.0053 17.0 0.0 2.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain 3-HAO PF06052.12 PVD25825.1 - 1.1e-63 213.4 0.2 2.1e-62 209.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 PVD25825.1 - 2e-09 37.0 0.0 3.7e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 PVD25825.1 - 4.6e-06 26.2 0.2 0.12 12.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 PVD25825.1 - 0.0027 17.6 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 PVD25825.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 Cupin 2OG-FeII_Oxy_5 PF13759.6 PVD25825.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ABC_trans_CmpB PF06541.11 PVD25826.1 - 2.6e-09 37.5 9.8 3.3e-09 37.2 9.8 1.1 1 0 0 1 1 1 1 Putative ABC-transporter type IV Eapp_C PF10238.9 PVD25827.1 - 2e-48 164.2 6.9 2e-48 164.2 6.9 2.6 2 1 0 2 2 2 1 E2F-associated phosphoprotein C1_4 PF07975.12 PVD25827.1 - 0.011 15.9 5.8 0.017 15.3 2.2 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain Yippee-Mis18 PF03226.14 PVD25827.1 - 0.078 13.2 5.5 0.34 11.1 5.5 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4083 PF13314.6 PVD25827.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) IBR PF01485.21 PVD25827.1 - 0.44 10.8 6.5 0.43 10.8 1.9 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain GAIN_A PF18619.1 PVD25827.1 - 7.2 6.9 8.9 29 5.0 0.4 3.1 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A WD40 PF00400.32 PVD25829.1 - 4.3e-37 125.5 20.2 0.0001 23.0 0.0 11.9 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25829.1 - 1.3e-10 41.5 0.4 0.00027 21.1 0.0 6.1 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 PVD25829.1 - 0.0039 16.5 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SgrR_N PF12793.7 PVD25829.1 - 0.097 12.9 0.3 0.24 11.6 0.3 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term WD40_like PF17005.5 PVD25829.1 - 0.11 11.8 0.0 53 3.0 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain C2 PF00168.30 PVD25830.1 - 1.5e-30 105.5 0.0 3e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD25830.1 - 0.082 12.5 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain NIF PF03031.18 PVD25831.1 - 4.2e-35 120.8 0.0 7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase OPA3 PF07047.12 PVD25831.1 - 1.9e-23 82.6 0.5 1.9e-23 82.6 0.5 1.8 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) SlyX PF04102.12 PVD25831.1 - 2.8 8.6 6.2 1.3 9.7 1.1 2.6 2 0 0 2 2 2 0 SlyX DUF16 PF01519.16 PVD25831.1 - 2.9 8.4 6.0 3.4 8.2 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 MNNL PF07657.13 PVD25841.1 - 3.8e-24 84.5 3.2 8.3e-24 83.4 3.2 1.6 1 0 0 1 1 1 1 N terminus of Notch ligand DSL PF01414.19 PVD25841.1 - 2.8e-22 78.8 11.7 2.8e-22 78.8 11.7 2.1 2 0 0 2 2 2 1 Delta serrate ligand ChaC PF04752.12 PVD25845.1 - 7.6e-52 176.0 0.0 1e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein SNF2_N PF00176.23 PVD25847.1 - 5.1e-69 232.6 0.6 1.4e-68 231.2 0.6 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 PVD25847.1 - 1.9e-47 160.9 24.8 1.9e-47 160.9 24.8 3.8 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 PVD25847.1 - 2.1e-17 63.4 0.0 8e-17 61.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD25847.1 - 8.1e-07 29.2 4.3 1.2e-05 25.4 0.0 4.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PVD25847.1 - 6e-05 22.4 0.0 6e-05 22.4 0.0 3.4 4 0 0 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 Glyco_transf_4 PF13439.6 PVD25847.1 - 0.21 11.6 2.4 1.1e+02 2.7 2.5 3.8 3 1 0 3 3 3 0 Glycosyltransferase Family 4 RRM_1 PF00076.22 PVD25848.1 - 1.5e-33 114.4 0.1 2.8e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD25848.1 - 0.00036 20.5 0.2 0.00036 20.5 0.2 2.7 2 1 1 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 PVD25848.1 - 0.00055 19.7 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PVD25848.1 - 0.0016 18.4 0.5 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 PVD25848.1 - 0.016 14.8 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 PVD25848.1 - 0.081 12.6 0.1 0.82 9.4 0.1 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated DUF936 PF06075.12 PVD25848.1 - 3.8 6.3 34.8 4.7 6.0 34.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.9 PVD25848.1 - 6.9 5.1 31.1 8.5 4.8 31.1 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 PVD25848.1 - 9.8 3.1 20.6 11 2.9 20.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FEZ PF07763.13 PVD25849.1 - 1.5e-85 286.8 15.7 2.2e-85 286.2 15.7 1.2 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 PVD25849.1 - 0.0086 16.1 13.5 0.13 12.3 2.3 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF5102) DUF4727 PF15856.5 PVD25849.1 - 0.072 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) BPL_N PF09825.9 PVD25849.1 - 1.2 8.1 4.0 2.1 7.3 4.0 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal GTP_EFTU PF00009.27 PVD25850.1 - 2.1e-32 112.3 7.7 7.5e-32 110.4 2.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PVD25850.1 - 4.6e-26 91.0 0.1 2.1e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PVD25850.1 - 8.9e-09 35.4 0.0 9.1e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD25850.1 - 2.7e-06 27.0 0.6 1e-05 25.1 0.1 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PVD25850.1 - 0.0012 18.9 0.1 0.0034 17.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU_D2 PF03144.25 PVD25850.1 - 0.0013 19.1 0.7 2.1 8.8 0.1 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.10 PVD25850.1 - 0.002 17.6 0.0 0.007 15.8 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PVD25850.1 - 0.0032 17.6 0.4 2.9 7.9 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AAA_26 PF13500.6 PVD25850.1 - 0.0064 16.3 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain SH3_2 PF07653.17 PVD25850.1 - 0.01 15.5 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain PduV-EutP PF10662.9 PVD25850.1 - 0.011 15.5 0.1 0.038 13.7 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 PVD25850.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 PVD25850.1 - 0.031 13.2 0.4 0.082 11.9 0.4 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MFS_1 PF07690.16 PVD25851.1 - 1.7e-10 40.4 30.6 3.1e-10 39.5 30.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 PVD25851.1 - 0.34 10.4 4.5 0.28 10.7 0.1 2.5 2 0 0 2 2 2 0 E1-E2 ATPase MFS_1 PF07690.16 PVD25852.1 - 4.2e-22 78.6 22.2 4.2e-22 78.6 22.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily GRIP PF01465.20 PVD25852.1 - 0.024 14.5 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 GRIP domain MRAP PF15183.6 PVD25852.1 - 0.68 9.9 5.4 1.4 8.9 0.5 3.1 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family MFS_1 PF07690.16 PVD25853.1 - 4.7e-10 38.9 34.7 7.7e-07 28.3 19.0 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily OppC_N PF12911.7 PVD25853.1 - 0.019 15.0 1.0 0.075 13.0 0.1 2.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C zf-C4 PF00105.18 PVD25855.1 - 1.4e-31 108.7 12.4 4.6e-31 107.1 12.4 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD25855.1 - 1.7e-23 83.3 0.3 3.1e-23 82.4 0.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD25859.1 - 3.7e-32 110.6 12.0 7.2e-32 109.7 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD25859.1 - 3.3e-14 53.0 0.1 6.4e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Mersacidin PF16934.5 PVD25860.1 - 0.028 14.2 2.3 0.039 13.7 2.3 1.2 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) DUF2057 PF09829.9 PVD25860.1 - 0.22 11.7 3.6 0.25 11.5 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Glycos_transf_2 PF00535.26 PVD25861.1 - 9.9e-27 93.8 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD25861.1 - 3.2e-14 53.3 7.1 4.7e-14 52.7 7.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PVD25861.1 - 1.1e-06 28.7 0.0 3.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD25861.1 - 5.4e-06 26.1 0.0 9.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 PVD25861.1 - 0.00047 20.8 0.9 0.027 15.2 0.7 2.5 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like PKD_3 PF16820.5 PVD25861.1 - 0.088 12.6 0.0 0.52 10.1 0.0 2.3 3 0 0 3 3 3 0 PKD-like domain Methyltransf_31 PF13847.6 PVD25862.1 - 4.1e-12 46.2 0.0 2.2e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PVD25862.1 - 2e-11 44.3 0.1 3.3e-10 40.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD25862.1 - 1.4e-10 41.3 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD25862.1 - 4.5e-10 40.1 0.2 3.7e-08 34.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD25862.1 - 3.3e-07 31.0 0.2 1.4e-05 25.7 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Sam68-YY PF16568.5 PVD25862.1 - 0.25 12.1 1.8 0.47 11.2 1.8 1.4 1 0 0 1 1 1 0 Tyrosine-rich domain of Sam68 TSNAXIP1_N PF15739.5 PVD25863.1 - 1e-19 70.9 6.7 1e-19 70.9 6.7 2.0 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus GAS PF13851.6 PVD25863.1 - 5e-05 22.7 19.7 0.0012 18.3 9.8 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding HALZ PF02183.18 PVD25863.1 - 0.0078 16.4 3.1 0.0078 16.4 3.1 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 PVD25863.1 - 0.038 13.9 13.1 0.054 13.4 12.3 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain bZIP_1 PF00170.21 PVD25863.1 - 0.07 13.2 8.9 0.046 13.8 4.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor NPV_P10 PF05531.12 PVD25863.1 - 0.21 12.1 2.3 5.8 7.5 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 PVD25863.1 - 0.62 10.7 6.3 5.7 7.6 0.4 3.6 4 0 0 4 4 4 0 SlyX V_ATPase_I PF01496.19 PVD25863.1 - 1.9 6.3 8.7 3.1 5.6 8.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 PVD25863.1 - 4.4 7.3 16.3 13 5.8 13.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 PVD25863.1 - 7.5 7.1 15.7 29 5.2 15.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region FragX_IP PF05994.11 PVD25864.1 - 0 1125.1 7.9 0 1120.3 4.7 2.1 1 1 1 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 PVD25864.1 - 5.9e-06 25.8 4.9 2.8e-05 23.5 4.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) BP28CT PF08146.12 PVD25864.1 - 0.033 14.0 0.3 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 BP28CT (NUC211) domain CD36 PF01130.21 PVD25865.1 - 3.2e-22 78.7 3.0 4.1e-12 45.4 0.1 4.0 4 0 0 4 4 4 4 CD36 family Ribonuclease_T2 PF00445.18 PVD25866.1 - 3.5e-46 157.7 2.5 4.4e-46 157.4 2.5 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4913 PF16259.5 PVD25866.1 - 0.044 13.9 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Ribonuclease_T2 PF00445.18 PVD25867.1 - 2.3e-38 132.2 0.0 2.7e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family HYLS1_C PF15311.6 PVD25868.1 - 3.1e-32 111.2 4.4 3.1e-32 111.2 4.4 2.0 2 1 1 3 3 3 1 Hydrolethalus syndrome protein 1 C-terminus Abhydrolase_2 PF02230.16 PVD25869.1 - 8.8e-36 123.7 0.0 9.6e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 PVD25869.1 - 3e-06 26.7 0.2 0.002 17.5 0.2 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD25869.1 - 4.1e-06 27.6 0.3 7e-06 26.8 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD25869.1 - 3.1e-05 23.7 0.2 5.6e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PVD25869.1 - 0.00073 19.4 0.0 0.00089 19.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 PVD25869.1 - 0.00079 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 PVD25869.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PVD25869.1 - 0.0017 17.9 0.2 0.16 11.4 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 PVD25869.1 - 0.013 15.4 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 PVD25869.1 - 0.017 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 PVD25869.1 - 0.022 14.4 0.0 0.07 12.8 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) MDMPI_C PF07398.11 PVD25869.1 - 0.045 14.6 0.0 0.073 13.9 0.0 1.3 1 0 0 1 1 1 0 MDMPI C-terminal domain Thioesterase PF00975.20 PVD25869.1 - 0.087 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 PVD25869.1 - 0.099 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Rubis-subs-bind PF09273.11 PVD25870.1 - 4.9e-27 95.2 1.4 9.3e-27 94.3 1.4 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PVD25870.1 - 1.1e-14 55.1 0.0 2.7e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 SET domain Hormone_1 PF00103.20 PVD25870.1 - 0.0049 16.6 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 Somatotropin hormone family Cyclin_N PF00134.23 PVD25871.1 - 1.1e-06 28.4 0.2 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PVD25871.1 - 0.0012 18.9 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 PVD25871.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain 7tm_3 PF00003.22 PVD25872.1 - 2.3e-44 151.9 24.9 3.2e-44 151.4 24.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EGF_3 PF12947.7 PVD25872.1 - 0.00078 19.6 3.1 0.0019 18.3 3.1 1.7 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 PVD25872.1 - 0.0079 16.4 4.1 0.0079 16.4 4.1 2.8 2 0 0 2 2 2 1 Calcium-binding EGF domain Osw5 PF17062.5 PVD25872.1 - 4.4 7.5 9.0 0.37 10.9 1.9 2.7 1 1 2 3 3 3 0 Outer spore wall 5 AhpC-TSA_2 PF13911.6 PVD25874.1 - 1.7e-11 44.2 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PVD25874.1 - 9.8e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Sec23_trunk PF04811.15 PVD25875.1 - 5e-78 262.0 0.0 8.1e-78 261.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PVD25875.1 - 1.4e-33 115.5 0.0 3.5e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PVD25875.1 - 6.3e-27 93.4 1.3 8.8e-27 92.9 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 PVD25875.1 - 3.2e-14 52.6 0.2 1e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 PVD25875.1 - 1.1e-07 31.8 1.8 2.3e-07 30.8 1.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger EF-hand_7 PF13499.6 PVD25876.1 - 2.5e-19 69.5 5.6 2.8e-14 53.3 3.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD25876.1 - 2.2e-18 64.5 2.5 2.5e-07 30.1 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PVD25876.1 - 3e-17 60.8 9.3 8.5e-07 28.1 0.5 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 PVD25876.1 - 1.3e-06 27.7 3.8 0.0044 16.5 0.1 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 PVD25876.1 - 6.5e-05 23.2 1.2 0.0012 19.2 0.6 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PVD25876.1 - 0.00014 21.6 9.1 0.00015 21.5 2.8 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 PVD25876.1 - 0.02 14.8 3.5 0.14 12.1 1.9 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DIMCO_N PF16844.5 PVD25876.1 - 0.022 15.1 0.1 0.065 13.6 0.1 1.9 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal RST PF12174.8 PVD25876.1 - 0.07 13.1 0.4 0.34 10.8 0.1 2.4 2 1 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain MHC_I PF00129.18 PVD25876.1 - 0.08 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 CIA30 PF08547.12 PVD25877.1 - 2e-40 138.4 0.2 2.6e-40 138.0 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 PVD25877.1 - 3.2e-06 27.2 0.2 6.4e-06 26.2 0.2 1.6 1 1 0 1 1 1 1 Carbohydrate binding domain (family 11) Acetyltransf_1 PF00583.25 PVD25878.1 - 9.4e-10 38.8 0.0 1.2e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD25878.1 - 2.2e-07 31.2 0.1 3.6e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD25878.1 - 3.1e-06 27.2 0.2 4.3e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 PVD25878.1 - 0.01 15.3 0.2 0.016 14.7 0.2 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Serpentine_r_xa PF03383.15 PVD25879.1 - 3.1e-06 27.2 0.4 4.1e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 PVD25879.1 - 5.8e-06 26.1 1.5 6.8e-06 25.9 1.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD25879.1 - 9.1e-05 22.2 2.4 0.00011 21.9 2.4 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 PVD25879.1 - 0.00088 18.7 1.5 0.0011 18.4 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD25880.1 - 6.5e-08 32.2 13.5 9.5e-08 31.7 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD25880.1 - 1e-05 25.4 8.7 1e-05 25.4 8.7 2.2 2 0 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD25880.1 - 0.0011 18.7 13.2 0.0011 18.7 13.2 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srx PF10328.9 PVD25882.1 - 0.00059 19.5 1.3 0.00089 19.0 1.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD25882.1 - 0.015 15.3 0.2 0.028 14.4 0.2 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa MFS_2 PF13347.6 PVD25882.1 - 0.047 12.3 3.5 0.066 11.8 3.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF3673 PF12425.8 PVD25883.1 - 0.00081 19.3 8.0 1.1e+02 2.8 0.0 7.8 9 0 0 9 9 9 0 Protein of unknown function (DUF3673) Integrase_Zn PF02022.19 PVD25883.1 - 0.00082 19.3 15.7 48 4.0 0.1 7.8 9 0 0 9 9 9 0 Integrase Zinc binding domain Sad1_UNC PF07738.13 PVD25883.1 - 0.0013 18.7 4.3 78 3.3 0.0 6.6 1 1 8 9 9 9 0 Sad1 / UNC-like C-terminal Phi-29_GP4 PF05464.11 PVD25883.1 - 0.017 15.4 22.1 1.1e+02 3.1 0.0 9.0 10 0 0 10 10 10 0 Phi-29-like late genes activator (early protein GP4) Ig_Tie2_1 PF10430.9 PVD25883.1 - 0.041 14.3 31.6 19 5.8 1.1 7.8 1 1 8 9 9 9 0 Tie-2 Ig-like domain 1 eIF2_C PF09173.11 PVD25883.1 - 0.061 13.6 21.2 1.7e+02 2.6 0.1 9.4 10 0 0 10 10 10 0 Initiation factor eIF2 gamma, C terminal AMP-binding_C_2 PF14535.6 PVD25883.1 - 1.3 9.3 13.8 2.1e+02 2.3 0.0 7.6 10 0 0 10 10 10 0 AMP-binding enzyme C-terminal domain Peptidase_Mx PF15887.5 PVD25883.1 - 1.7 8.0 5.7 15 4.9 0.0 4.5 4 1 1 5 5 5 0 Putative zinc-binding metallo-peptidase DUF5058 PF16481.5 PVD25883.1 - 3.1 7.4 8.8 48 3.5 0.0 5.4 3 1 3 7 7 7 0 Domain of unknown function (DUF5058) ESPR PF13018.6 PVD25883.1 - 7.6 6.4 33.2 1.1e+02 2.7 0.1 9.2 9 0 0 9 9 9 0 Extended Signal Peptide of Type V secretion system 7TM_GPCR_Srw PF10324.9 PVD25885.1 - 8.9e-09 35.1 18.0 2.6e-08 33.5 18.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD25885.1 - 4.2e-05 23.0 13.8 9.7e-05 21.8 13.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD25886.1 - 3.5e-10 39.7 10.1 5e-10 39.2 10.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD25886.1 - 1.8e-05 24.2 8.1 2.1e-05 24.0 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DHHC PF01529.20 PVD25886.1 - 3.1 7.9 10.2 1.5 8.9 7.2 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase 7TM_GPCR_Srw PF10324.9 PVD25887.1 - 1.8e-10 40.6 13.3 5e-10 39.2 13.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD25887.1 - 6.8e-07 28.9 8.1 8e-07 28.6 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NMN_transporter PF04973.12 PVD25887.1 - 0.002 18.1 5.9 0.0028 17.6 5.9 1.2 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter SecD-TM1 PF13721.6 PVD25887.1 - 0.077 13.5 0.6 0.13 12.7 0.3 1.6 1 1 0 1 1 1 0 SecD export protein N-terminal TM region DHHC PF01529.20 PVD25887.1 - 0.67 10.1 7.3 0.98 9.5 6.6 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4834 PF16118.5 PVD25887.1 - 5.1 8.1 5.8 0.73 10.8 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) 7tm_1 PF00001.21 PVD25888.1 - 9.9e-07 28.3 8.6 1.2e-06 28.1 8.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD25888.1 - 8e-05 22.4 12.4 9.8e-05 22.1 12.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD25888.1 - 0.0029 17.6 5.2 0.0045 17.0 5.2 1.4 1 1 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa Srg PF02118.21 PVD25888.1 - 0.0087 15.7 5.0 0.0087 15.7 5.0 1.6 1 1 0 1 1 1 1 Srg family chemoreceptor IlvB_leader PF08049.11 PVD25888.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 IlvB leader peptide DUF1622 PF07784.11 PVD25888.1 - 0.083 12.8 0.7 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) PNTB_4TM PF12769.7 PVD25888.1 - 0.19 12.2 3.2 0.23 12.0 0.4 2.3 1 1 1 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Ras PF00071.22 PVD25889.1 - 3.8e-27 94.9 0.0 4.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25889.1 - 2e-07 31.2 0.0 2.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Tmemb_170 PF10190.9 PVD25890.1 - 1.8e-21 76.5 1.9 3.1e-21 75.7 1.9 1.3 1 0 0 1 1 1 1 Putative transmembrane protein 170 Cep57_CLD_2 PF14197.6 PVD25890.1 - 0.0012 18.8 1.6 0.0012 18.8 1.6 10.9 8 3 5 13 13 13 1 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 PVD25890.1 - 0.022 14.6 0.3 14 5.6 0.0 4.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 PVD25890.1 - 0.55 9.1 84.7 0.036 12.9 6.0 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein Ank_2 PF12796.7 PVD25891.1 - 8.4e-61 202.5 10.3 2e-16 60.3 0.0 5.7 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD25891.1 - 4.8e-56 186.4 3.7 3.5e-13 49.8 0.1 9.4 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD25891.1 - 5.3e-49 163.7 7.3 2.9e-11 43.4 0.2 9.3 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD25891.1 - 1e-48 157.6 1.3 9.8e-07 28.6 0.0 11.3 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 PVD25891.1 - 1.6e-39 132.6 12.9 1.2e-05 25.5 0.1 11.2 10 1 1 11 11 11 6 Ankyrin repeat EF-hand_1 PF00036.32 PVD25891.1 - 3.7e-08 32.4 1.5 0.0023 17.4 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD25891.1 - 1.4e-07 31.9 0.2 3.9e-07 30.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD25891.1 - 2.8e-07 30.3 1.5 0.011 15.5 0.2 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD25891.1 - 4.6e-06 26.1 1.5 0.053 13.5 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD25891.1 - 0.18 11.4 3.0 8.3 6.1 0.3 2.6 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 PVD25892.1 - 2.2e-63 214.1 0.0 3.3e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25892.1 - 1.4e-26 93.3 0.0 2.8e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase bZIP_2 PF07716.15 PVD25892.1 - 1.6e-10 40.9 7.7 1.6e-10 40.9 7.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Kinase-like PF14531.6 PVD25892.1 - 3.4e-06 26.6 0.0 6.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD25892.1 - 0.0075 15.6 0.9 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 PVD25892.1 - 0.0095 16.0 7.7 0.0095 16.0 7.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor RIO1 PF01163.22 PVD25892.1 - 0.083 12.5 0.1 0.083 12.5 0.1 1.9 2 0 0 2 2 2 0 RIO1 family CRC_subunit PF08624.10 PVD25893.1 - 0.017 15.6 0.0 0.054 13.9 0.0 1.8 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit MRP-L46 PF11788.8 PVD25893.1 - 8.9 7.1 7.6 1.3e+02 3.3 5.1 3.1 2 1 1 3 3 3 0 39S mitochondrial ribosomal protein L46 DUF5600 PF18150.1 PVD25894.1 - 1.5e-27 96.3 0.8 2.9e-27 95.4 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 PVD25894.1 - 3.7e-19 68.6 0.9 5.8e-19 68.0 0.1 1.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD25894.1 - 0.00066 19.0 0.0 0.0024 17.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PVD25894.1 - 0.035 14.5 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 PVD25894.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 PVD25894.1 - 0.11 12.5 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain PUL PF08324.11 PVD25894.1 - 0.2 10.8 0.3 2.9 7.1 0.0 2.1 2 1 1 3 3 3 0 PUL domain EHD_N PF16880.5 PVD25895.1 - 5.1e-18 64.7 3.5 5.1e-18 64.7 3.5 1.8 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 PVD25895.1 - 1.4e-14 54.5 0.0 3.4e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PVD25895.1 - 5.2e-09 36.2 0.0 9.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 PVD25895.1 - 3.7e-05 24.3 1.2 8.9e-05 23.0 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) GTP_EFTU PF00009.27 PVD25895.1 - 0.00061 19.4 0.0 0.003 17.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 PVD25895.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 PVD25895.1 - 0.0055 16.9 0.0 0.91 9.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD25895.1 - 0.0057 16.6 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 PVD25895.1 - 0.0071 15.7 0.0 0.06 12.7 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PVD25895.1 - 0.02 14.4 0.0 0.99 8.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 PVD25895.1 - 0.024 14.3 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 PVD25895.1 - 0.1 12.2 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Ras family AIG1 PF04548.16 PVD25895.1 - 0.13 11.6 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 AIG1 family TsaE PF02367.17 PVD25895.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 PVD25895.1 - 0.16 11.2 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 PVD25895.1 - 0.17 12.2 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 PVD25896.1 - 2.5e-08 34.2 0.0 4.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Laminin_II PF06009.12 PVD25897.1 - 0.01 15.8 13.1 0.01 15.8 13.1 10.8 1 1 9 12 12 12 0 Laminin Domain II Cep57_CLD_2 PF14197.6 PVD25897.1 - 0.011 15.7 4.5 0.011 15.7 4.5 12.9 9 5 3 12 12 12 0 Centrosome localisation domain of PPC89 DUF3800 PF12686.7 PVD25897.1 - 0.013 16.1 7.3 6.9e+02 0.9 6.9 5.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4834 PF16118.5 PVD25897.1 - 0.16 13.0 0.1 0.16 13.0 0.1 7.9 8 1 0 8 8 8 0 Domain of unknown function (DUF4834) ABC_export PF16962.5 PVD25897.1 - 2 6.8 6.0 2.6 6.4 1.4 2.1 2 0 0 2 2 2 0 Putative ABC exporter Hydrolase PF00702.26 PVD25898.1 - 3.9e-07 30.6 0.7 4.2e-07 30.5 0.1 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PVD25898.1 - 4.5e-05 23.6 0.3 0.0027 17.8 0.0 2.7 2 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD25898.1 - 0.023 14.7 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like NOA36 PF06524.12 PVD25898.1 - 5.3 6.3 13.9 9.3 5.5 13.9 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_12 PF13424.6 PVD25899.1 - 2.5e-75 248.8 23.9 4.7e-21 74.9 0.9 5.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 PVD25899.1 - 1e-64 212.8 10.6 1.4e-15 56.6 0.0 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 PVD25899.1 - 1.2e-34 115.7 12.3 4.9e-06 26.2 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD25899.1 - 1.2e-29 100.8 30.0 1.6e-07 30.8 0.5 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 PVD25899.1 - 2.8e-22 77.0 26.4 0.00031 20.6 2.8 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD25899.1 - 2.1e-19 68.0 23.1 0.0017 18.4 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD25899.1 - 8.7e-15 55.1 8.2 0.00099 19.7 0.1 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD25899.1 - 5.8e-13 48.5 7.5 0.18 12.7 0.1 6.6 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD25899.1 - 1.7e-12 47.4 0.6 1.7e-12 47.4 0.6 2.8 3 1 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 PVD25899.1 - 3.8e-10 39.4 9.7 0.044 14.2 0.3 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 PVD25899.1 - 2.5e-09 36.9 0.0 11 7.0 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD25899.1 - 3.7e-09 36.9 11.1 0.0013 19.2 0.6 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD25899.1 - 3.9e-08 33.4 8.8 0.0011 19.2 0.1 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 PVD25899.1 - 2e-06 27.5 1.6 3.1e-06 26.8 0.6 1.9 2 1 0 2 2 1 1 Soluble NSF attachment protein, SNAP PPR PF01535.20 PVD25899.1 - 0.0015 18.6 7.3 0.39 11.1 0.0 5.7 7 0 0 7 7 5 1 PPR repeat TPR_3 PF07720.12 PVD25899.1 - 0.0046 16.9 13.5 3.9 7.6 0.4 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat HALZ PF02183.18 PVD25899.1 - 0.011 16.0 0.2 0.049 13.9 0.2 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Csm1_N PF18504.1 PVD25899.1 - 0.08 13.3 2.5 0.42 11.0 2.5 2.3 1 0 0 1 1 1 0 Csm1 N-terminal domain GHL5 PF14872.6 PVD25899.1 - 0.082 10.9 1.1 0.13 10.2 1.1 1.3 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF627 PF04781.12 PVD25899.1 - 0.094 12.7 4.1 4.3 7.4 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF627) YfdX PF10938.8 PVD25899.1 - 0.13 12.1 3.9 13 5.7 0.8 3.3 3 1 0 3 3 2 0 YfdX protein RhoGAP PF00620.27 PVD25899.1 - 0.2 11.5 1.3 1.6 8.6 0.2 2.7 1 1 1 2 2 2 0 RhoGAP domain Wzy_C_2 PF11846.8 PVD25899.1 - 0.26 11.2 1.4 35 4.2 0.1 3.9 3 1 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal PPR_2 PF13041.6 PVD25899.1 - 0.31 11.3 8.4 2 8.7 0.0 4.4 6 0 0 6 6 4 0 PPR repeat family DUF2225 PF09986.9 PVD25899.1 - 0.34 10.6 8.8 0.87 9.3 1.8 3.3 3 1 1 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 PVD25899.1 - 1.4 9.7 18.4 0.83 10.4 0.5 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1897 PF09005.10 PVD25899.1 - 1.5 8.4 4.3 9.3 5.8 0.2 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF1897) JIP_LZII PF16471.5 PVD25899.1 - 1.5 9.0 8.1 0.23 11.7 1.5 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PVD25899.1 - 2.6 8.2 11.3 1.4 9.1 0.3 4.1 3 1 1 4 4 4 0 bZIP transcription factor TPR_11 PF13414.6 PVD25899.1 - 6.5 6.5 30.1 0.16 11.7 0.3 6.3 7 0 0 7 7 6 0 TPR repeat eIF-5_eIF-2B PF01873.17 PVD25900.1 - 8e-42 141.8 0.2 2.1e-41 140.5 0.2 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 PVD25900.1 - 1.2e-21 76.7 2.0 1.2e-21 76.7 2.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon SRI PF08236.11 PVD25900.1 - 0.011 15.9 0.4 0.011 15.9 0.4 3.2 3 1 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain C2-set PF05790.15 PVD25900.1 - 0.049 13.8 0.7 0.14 12.3 0.7 1.7 1 0 0 1 1 1 0 Immunoglobulin C2-set domain ADD_DNMT3 PF17980.1 PVD25900.1 - 0.094 12.7 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Cyt-b5 PF00173.28 PVD25901.1 - 0.0013 18.8 0.1 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Vasohibin PF14822.6 PVD25902.1 - 5.5e-104 346.7 0.1 6.7e-104 346.4 0.1 1.1 1 0 0 1 1 1 1 Vasohibin Exo_endo_phos PF03372.23 PVD25903.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RyR PF02026.16 PVD25903.1 - 1.4 9.2 6.3 0.82 9.9 0.5 2.5 2 0 0 2 2 2 0 RyR domain Ras PF00071.22 PVD25904.1 - 1.9e-48 164.1 0.0 2.3e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD25904.1 - 5e-19 68.7 0.0 7.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD25904.1 - 0.00022 20.7 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 PVD25904.1 - 0.023 14.3 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Hfq PF17209.3 PVD25904.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SNF2_N PF00176.23 PVD25904.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain TniB PF05621.11 PVD25904.1 - 0.25 10.7 0.0 0.61 9.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein CCDC32 PF14989.6 PVD25906.1 - 5e-20 72.0 0.8 9.4e-20 71.2 0.8 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing 32 DUF563 PF04577.14 PVD25906.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) zf-C2H2 PF00096.26 PVD25908.1 - 5.8e-24 83.2 43.8 4.3e-05 23.7 3.0 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD25908.1 - 2.9e-16 59.1 45.6 6.8e-08 32.6 1.5 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD25908.1 - 2.2e-13 49.8 43.9 0.012 16.3 3.0 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD25908.1 - 2.8e-06 27.0 32.4 9.3e-05 22.1 5.0 4.6 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 PVD25908.1 - 0.0011 18.9 11.0 0.062 13.4 0.6 2.8 2 1 0 2 2 2 2 Zinc-finger DUF3268 PF11672.8 PVD25908.1 - 0.0015 18.8 11.2 0.057 13.8 0.4 2.3 2 0 0 2 2 2 2 zinc-finger-containing domain NOA36 PF06524.12 PVD25908.1 - 0.0021 17.4 8.1 0.0021 17.4 8.1 2.5 2 0 0 2 2 2 1 NOA36 protein GAGA PF09237.11 PVD25908.1 - 0.0048 16.7 7.7 0.19 11.5 0.5 2.9 2 1 1 3 3 3 2 GAGA factor zf-C2H2_jaz PF12171.8 PVD25908.1 - 0.035 14.4 28.5 2.2 8.7 2.0 5.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 PVD25908.1 - 0.38 11.2 11.5 17 5.9 1.5 3.7 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Di19 PF05605.12 PVD25908.1 - 4.1 7.8 25.2 0.35 11.2 5.3 3.2 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding A2L_zn_ribbon PF08792.10 PVD25910.1 - 0.01 15.5 0.2 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF5454 PF17535.2 PVD25910.1 - 0.17 11.3 0.1 0.23 10.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5454) PRIMA1 PF16101.5 PVD25915.1 - 0.29 11.2 2.5 0.5 10.4 2.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD25915.1 - 0.51 9.8 3.6 0.63 9.5 3.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SelP_N PF04592.14 PVD25915.1 - 0.81 9.0 5.5 1.1 8.7 5.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Holin_BlyA PF05102.12 PVD25916.1 - 4.8 7.2 6.1 6.7 6.7 6.1 1.2 1 0 0 1 1 1 0 holin, BlyA family DUF1336 PF07059.12 PVD25921.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) SRCR PF00530.18 PVD25922.1 - 1.7e-47 160.0 6.6 2.9e-18 66.2 1.2 3.5 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Kelch_4 PF13418.6 PVD25922.1 - 3.9e-19 68.4 6.9 5.4e-09 35.9 0.0 5.6 6 0 0 6 6 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD25922.1 - 2.1e-15 56.3 0.2 2.8e-05 24.0 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 PVD25922.1 - 4.7e-15 55.2 1.0 1.7e-07 31.3 0.0 3.8 3 0 0 3 3 3 2 Kelch motif SRCR_2 PF15494.6 PVD25922.1 - 5.5e-14 52.5 4.3 3.8e-06 27.3 0.2 3.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Kelch_3 PF13415.6 PVD25922.1 - 4.1e-13 49.3 8.7 2.2e-06 27.8 0.2 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD25922.1 - 2.1e-12 46.4 0.2 1.1e-05 24.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Hepsin-SRCR PF09272.10 PVD25922.1 - 8.1e-10 39.2 1.6 0.044 14.3 0.1 3.8 3 0 0 3 3 3 3 Hepsin, SRCR domain Kelch_2 PF07646.15 PVD25922.1 - 5.2e-09 35.7 0.4 0.012 15.6 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Beta_helix PF13229.6 PVD25922.1 - 3e-07 30.4 81.5 0.019 14.8 3.7 7.2 5 1 1 6 6 6 5 Right handed beta helix region Na_Ca_ex PF01699.24 PVD25922.1 - 0.09 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Sodium/calcium exchanger protein PPP4R2 PF09184.11 PVD25922.1 - 1.8 8.1 14.5 2.8 7.4 14.5 1.2 1 0 0 1 1 1 0 PPP4R2 GAPT PF11770.8 PVD25922.1 - 6 6.7 9.2 14 5.6 0.0 2.9 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) RVT_1 PF00078.27 PVD25925.1 - 0.002 17.7 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ETAA1 PF15350.6 PVD25926.1 - 2.9e-06 25.9 1.2 2.9e-06 25.9 1.2 1.8 2 0 0 2 2 2 1 Ewing's tumour-associated antigen 1 homologue PMT_4TMC PF16192.5 PVD25927.1 - 1.5e-50 171.5 9.0 1.5e-50 171.5 9.0 2.1 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 PVD25927.1 - 1.4e-29 103.4 16.0 2e-26 93.0 0.0 3.0 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 PVD25927.1 - 3e-24 85.9 0.4 7.1e-24 84.7 0.4 1.6 1 0 0 1 1 1 1 MIR domain RVT_1 PF00078.27 PVD25927.1 - 0.0002 20.9 0.1 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 PVD25927.1 - 0.0012 19.0 0.1 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4200 PF13863.6 PVD25928.1 - 7.8e-26 90.8 23.3 7.8e-26 90.8 23.3 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) Val_tRNA-synt_C PF10458.9 PVD25928.1 - 0.021 15.1 1.4 0.021 15.1 1.4 4.3 4 1 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm DUF4472 PF14739.6 PVD25928.1 - 0.68 10.7 27.5 0.084 13.6 12.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Pox_A11 PF05061.13 PVD25928.1 - 2.1 7.5 8.0 1.2 8.3 6.2 1.5 1 1 0 1 1 1 0 Poxvirus A11 Protein Acetyltransf_11 PF13720.6 PVD25928.1 - 7.7 7.1 6.6 3.4 8.2 0.6 3.0 2 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UPF0564 PF10595.9 PVD25929.1 - 3.7e-56 190.8 55.8 3.7e-56 190.8 55.8 2.5 3 1 1 4 4 4 1 Uncharacterised protein family UPF0564 SH3_1 PF00018.28 PVD25930.1 - 8.1e-12 44.6 0.5 1.9e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD25930.1 - 1.2e-11 44.3 0.4 2.4e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD25930.1 - 2.9e-11 42.9 0.0 6.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BUD22 PF09073.10 PVD25930.1 - 0.0082 15.5 28.4 0.014 14.8 28.4 1.3 1 0 0 1 1 1 1 BUD22 hSH3 PF14603.6 PVD25930.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 PVD25930.1 - 0.086 13.1 0.1 0.39 11.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Pox_Ag35 PF03286.14 PVD25930.1 - 0.095 12.5 23.3 0.032 14.0 19.7 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2052 PF09747.9 PVD25930.1 - 0.29 11.3 32.1 0.3 11.2 28.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 PVD25930.1 - 0.31 10.7 37.1 0.61 9.7 37.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-N PF05238.13 PVD25930.1 - 0.34 10.2 9.3 0.51 9.6 9.3 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 PVD25930.1 - 0.35 9.6 12.9 0.52 9.0 12.9 1.3 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 PVD25930.1 - 0.38 9.7 11.1 0.75 8.7 11.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 PVD25930.1 - 0.47 10.6 16.1 0.28 11.4 12.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 PVD25930.1 - 0.49 9.4 9.4 0.8 8.7 9.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 PVD25930.1 - 0.6 9.5 16.3 1.4 8.3 16.3 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 PVD25930.1 - 0.67 10.4 15.0 0.1 13.0 10.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF5523 PF17661.1 PVD25930.1 - 0.71 9.5 37.2 0.047 13.4 31.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Tim54 PF11711.8 PVD25930.1 - 0.72 8.6 18.9 1.8 7.3 18.9 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 PVD25930.1 - 0.86 8.9 31.2 0.039 13.3 23.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4820 PF16091.5 PVD25930.1 - 1.7 8.0 13.0 4.9 6.5 13.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF702 PF05142.12 PVD25930.1 - 2.4 8.6 5.9 19 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF702) DUF4045 PF13254.6 PVD25930.1 - 3 7.4 17.6 5.4 6.6 17.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CLN3 PF02487.17 PVD25930.1 - 3.1 6.8 7.7 5.1 6.0 7.7 1.3 1 0 0 1 1 1 0 CLN3 protein Endostatin PF06482.11 PVD25930.1 - 4.4 6.7 6.9 7 6.0 4.9 2.2 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin TFIIF_alpha PF05793.12 PVD25930.1 - 5.7 5.4 37.4 1.7 7.1 30.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NPR3 PF03666.13 PVD25930.1 - 6.3 5.5 14.6 15 4.2 14.6 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FYDLN_acid PF09538.10 PVD25930.1 - 7.4 7.3 24.3 0.35 11.6 15.7 2.7 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 PVD25930.1 - 9.1 6.0 30.1 0.63 9.8 24.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GOLD_2 PF13897.6 PVD25931.1 - 4.2e-46 156.9 2.1 4.2e-46 156.9 2.1 2.4 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 PVD25931.1 - 0.018 15.2 3.4 0.024 14.8 0.0 2.7 3 1 0 3 3 3 0 Acyl CoA binding protein Put_Phosphatase PF06888.12 PVD25931.1 - 0.074 12.4 2.2 0.15 11.4 2.2 1.5 1 0 0 1 1 1 0 Putative Phosphatase SOBP PF15279.6 PVD25931.1 - 1.1 9.8 11.7 1.8 9.1 11.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pox_Ag35 PF03286.14 PVD25931.1 - 2.8 7.7 11.0 0.36 10.6 4.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Epiglycanin_C PF14654.6 PVD25934.1 - 0.45 10.6 1.5 0.53 10.4 0.7 1.5 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region TcdA_TcdB PF12919.7 PVD25935.1 - 0.036 13.4 0.3 0.043 13.1 0.3 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MHYT PF03707.16 PVD25938.1 - 0.1 12.8 1.0 0.19 11.9 1.0 1.4 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Sid-5 PF17204.3 PVD25938.1 - 0.97 9.7 2.5 0.59 10.3 0.3 1.7 2 0 0 2 2 2 0 Sid-5 family SPRY PF00622.28 PVD25940.1 - 3.6e-17 62.6 2.3 1.2e-05 25.3 0.2 4.9 4 2 0 4 4 4 4 SPRY domain TIR_2 PF13676.6 PVD25940.1 - 0.0046 17.5 0.0 0.0092 16.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain Sulfotransfer_1 PF00685.27 PVD25941.1 - 3.7e-05 23.3 0.1 0.022 14.2 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain EF-hand_7 PF13499.6 PVD25942.1 - 1.3e-25 89.6 11.5 6.2e-12 45.8 1.7 5.7 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD25942.1 - 4.4e-25 86.0 16.5 0.0005 19.4 0.0 7.6 6 1 1 7 7 7 6 EF hand EF-hand_1 PF00036.32 PVD25942.1 - 9.6e-24 81.1 12.1 0.00059 19.2 0.0 6.9 5 2 2 7 7 7 6 EF hand EF-hand_6 PF13405.6 PVD25942.1 - 4.2e-23 79.3 13.1 0.00061 19.5 0.3 7.5 4 2 3 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 PVD25942.1 - 4.3e-21 74.5 4.1 7.4e-05 22.5 0.0 5.4 4 1 1 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD25942.1 - 4.5e-06 27.0 7.1 7.1 7.0 0.2 5.8 3 2 3 6 6 6 3 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 PVD25942.1 - 0.00014 22.1 1.0 0.055 13.6 0.1 2.9 3 1 0 3 3 3 2 p25-alpha EF-hand_4 PF12763.7 PVD25942.1 - 0.0084 16.0 6.5 1.3 9.0 0.0 4.3 5 0 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand DUF543 PF04418.12 PVD25942.1 - 0.18 11.8 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) NHL PF01436.21 PVD25942.1 - 4.8 7.4 10.4 70 3.7 0.4 4.1 1 1 5 6 6 6 0 NHL repeat EF-hand_7 PF13499.6 PVD25943.1 - 8.7e-21 74.2 9.2 7.1e-07 29.6 0.2 5.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD25943.1 - 8.6e-19 66.1 17.8 0.00094 18.6 0.1 7.6 8 0 0 8 8 8 5 EF hand EF-hand_1 PF00036.32 PVD25943.1 - 3e-18 63.9 18.8 0.0055 16.2 0.1 7.3 6 1 1 7 7 7 6 EF hand EF-hand_6 PF13405.6 PVD25943.1 - 1.3e-17 62.2 22.4 0.0099 15.7 0.3 8.1 5 3 3 8 8 8 7 EF-hand domain EF-hand_8 PF13833.6 PVD25943.1 - 8.8e-13 47.9 12.7 0.05 13.5 0.1 6.0 4 2 2 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD25943.1 - 0.00033 21.0 3.2 6.3 7.2 0.0 4.5 1 1 3 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD25943.1 - 0.00037 20.6 9.5 4.6 7.5 0.1 5.6 5 2 0 5 5 5 1 Dockerin type I domain EF-hand_4 PF12763.7 PVD25943.1 - 0.0099 15.8 1.9 17 5.4 0.2 4.1 3 2 2 5 5 5 1 Cytoskeletal-regulatory complex EF hand WYL_2 PF10902.8 PVD25943.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.9 3 0 0 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold EF-hand_5 PF13202.6 PVD25944.1 - 2.9e-10 39.1 4.6 5e-05 22.6 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.32 PVD25944.1 - 7.2e-09 34.6 0.1 0.0013 18.2 0.0 2.9 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD25944.1 - 1.2e-08 34.2 1.7 0.0016 18.2 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD25944.1 - 4.9e-07 30.1 0.2 0.0062 17.0 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD25944.1 - 0.00016 21.4 0.0 0.078 12.8 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD25944.1 - 0.041 14.2 0.1 2.2 8.6 0.1 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SLBB PF10531.9 PVD25944.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 SLBB domain Peptidase_M28 PF04389.17 PVD25945.1 - 2e-21 76.6 0.0 4.5e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 PVD25945.1 - 3.2e-17 62.8 0.0 3.2e-17 62.8 0.0 5.0 4 2 1 6 6 6 1 Transferrin receptor-like dimerisation domain Nicastrin PF05450.15 PVD25945.1 - 0.017 14.6 0.7 0.049 13.1 0.0 2.0 2 0 0 2 2 2 0 Nicastrin Peptidase_M20 PF01546.28 PVD25945.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Methyltransf_14 PF08484.11 PVD25945.1 - 0.16 11.8 1.1 5.7 6.7 0.0 3.0 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain DUF1664 PF07889.12 PVD25945.1 - 0.51 10.4 40.5 1.3 9.1 1.8 6.8 5 1 2 7 7 7 0 Protein of unknown function (DUF1664) Peptidase_M28 PF04389.17 PVD25946.1 - 4.1e-20 72.3 0.0 9.1e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD25946.1 - 1.3e-19 70.0 0.0 7.5e-09 35.5 0.0 2.7 2 0 0 2 2 2 2 PA domain TFR_dimer PF04253.15 PVD25946.1 - 2.7e-09 37.2 0.0 6.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain ATP-synt_G PF04718.15 PVD25946.1 - 0.02 15.7 0.3 15 6.5 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Peptidase_M20 PF01546.28 PVD25946.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mycobact_memb PF05423.13 PVD25946.1 - 0.073 13.0 0.1 9.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Mycobacterium membrane protein AA_permease_2 PF13520.6 PVD25946.1 - 0.14 10.9 0.1 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Amino acid permease Caudo_bapla_RBP PF08931.10 PVD25946.1 - 0.18 11.3 3.4 6 6.3 0.2 2.3 2 0 0 2 2 2 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head FadA PF09403.10 PVD25946.1 - 0.57 10.7 2.1 8.9 6.9 0.1 2.9 3 0 0 3 3 3 0 Adhesion protein FadA PA PF02225.22 PVD25947.1 - 2.7e-10 40.1 0.0 8.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 PVD25947.1 - 6.6e-05 22.7 0.2 0.00054 19.7 0.0 2.2 1 1 0 2 2 2 1 Peptidase family M28 PMP22_Claudin PF00822.20 PVD25948.1 - 2.7e-09 37.1 6.2 4.5e-09 36.4 6.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD25948.1 - 2.3e-05 24.2 6.2 2.3e-05 24.2 6.2 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD25948.1 - 0.021 14.7 5.7 0.048 13.6 5.7 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4199 PF13858.6 PVD25948.1 - 0.089 13.2 4.6 0.13 12.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Amastin PF07344.11 PVD25948.1 - 0.1 12.5 9.4 0.29 10.9 9.4 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF4184 PF13803.6 PVD25948.1 - 0.21 11.3 2.1 0.57 9.9 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) adh_short PF00106.25 PVD25950.1 - 1.6e-29 102.8 3.3 5.8e-29 100.9 0.1 3.0 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD25950.1 - 5.8e-18 65.3 0.1 2e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD25950.1 - 1.1e-08 35.2 0.1 2.5e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD25950.1 - 6e-08 32.4 0.0 9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PVD25950.1 - 0.001 19.3 0.2 0.0026 18.0 0.2 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 PVD25950.1 - 0.0028 17.7 0.1 0.0075 16.3 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 PVD25950.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 PVD25950.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 PVD25950.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PVD25950.1 - 0.061 12.4 0.0 0.22 10.6 0.0 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 PVD25950.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RmlD_sub_bind PF04321.17 PVD25950.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Proteasome PF00227.26 PVD25951.1 - 4.8e-45 153.4 0.1 6.7e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PVD25951.1 - 1.1e-13 50.5 0.1 2.1e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CENP-K PF11802.8 PVD25952.1 - 2.3e-46 158.5 15.6 2.8e-46 158.3 15.6 1.0 1 0 0 1 1 1 1 Centromere-associated protein K Dynein_C PF18199.1 PVD25952.1 - 7.6 5.6 13.0 2.8 7.1 10.1 1.6 1 1 1 2 2 2 0 Dynein heavy chain C-terminal domain ADH_N_2 PF16884.5 PVD25953.1 - 7.6e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PVD25953.1 - 1.8e-17 63.5 0.0 3.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD25953.1 - 1.4e-12 48.8 0.0 3.6e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMPK1_CBM PF16561.5 PVD25955.1 - 7.5e-25 87.0 0.6 1.4e-24 86.1 0.6 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 PVD25955.1 - 4e-05 23.9 0.0 7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ependymin PF00811.18 PVD25956.1 - 2.6e-20 73.0 0.0 3.2e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 PVD25957.1 - 5.5e-35 120.4 0.0 9.2e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Ependymin 7tm_1 PF00001.21 PVD25958.1 - 8.5e-31 107.2 15.6 1.4e-15 57.4 7.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD25958.1 - 7.8e-09 35.3 12.9 1.7e-07 30.9 8.7 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4014 PF13198.6 PVD25958.1 - 0.17 12.3 1.0 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) ABC1 PF03109.16 PVD25959.1 - 3.4e-34 117.5 0.0 7.7e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family CoiA PF06054.11 PVD25959.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family Cm_res_leader PF08077.11 PVD25959.1 - 0.35 11.1 1.0 1.1 9.6 0.2 2.3 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide KH_1 PF00013.29 PVD25960.1 - 4.5e-40 135.3 14.3 3.3e-15 55.7 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 PVD25960.1 - 8.3e-09 35.2 13.0 0.0014 18.4 1.5 3.4 2 1 1 3 3 3 3 KH domain KH_4 PF13083.6 PVD25960.1 - 3.8e-05 23.5 3.1 0.25 11.3 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 PVD25960.1 - 0.00042 20.3 6.3 0.85 9.7 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 PVD25960.1 - 0.011 15.7 0.1 2.2 8.4 0.0 2.9 3 0 0 3 3 3 0 KH-like RNA-binding domain 3HCDH_N PF02737.18 PVD25961.1 - 5.6e-40 137.1 0.0 7.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PVD25961.1 - 4.7e-07 30.1 0.0 2.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 PVD25961.1 - 6.8e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 PVD25961.1 - 0.00043 19.9 0.1 0.0014 18.3 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 PVD25961.1 - 0.0027 18.0 0.0 0.0068 16.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 PVD25961.1 - 0.0056 16.3 0.1 0.0088 15.6 0.1 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 PVD25961.1 - 0.0078 16.7 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 PVD25961.1 - 0.012 16.2 0.0 0.027 15.1 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 PVD25961.1 - 0.015 15.8 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 PVD25961.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD25961.1 - 0.025 13.3 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 PVD25961.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 PVD25961.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GEMIN8 PF15348.6 PVD25962.1 - 0.0041 17.5 0.2 0.0063 16.8 0.2 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 PDZ PF00595.24 PVD25963.1 - 1.8e-07 31.4 0.4 3.6e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD25963.1 - 0.00026 21.2 0.1 0.00049 20.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD25963.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PsbH PF00737.20 PVD25964.1 - 1.4 8.7 4.2 0.96 9.2 0.9 2.0 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Cyt-b5 PF00173.28 PVD25965.1 - 4.6e-13 49.1 0.1 7e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS_DHEX PF18148.1 PVD25966.1 - 5.3e-48 161.2 2.2 1.2e-47 160.1 0.8 2.3 3 0 0 3 3 3 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 PVD25966.1 - 3e-23 82.3 1.6 5.4e-23 81.5 0.2 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 PVD25966.1 - 2.1e-16 59.8 0.0 7.3e-16 58.0 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 PVD25966.1 - 8.7e-10 38.5 0.0 2.9e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 PVD25966.1 - 0.0016 18.2 0.2 0.0046 16.7 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain DUF2428 PF10350.9 PVD25967.1 - 5.1e-81 271.9 1.5 8e-81 271.3 0.1 2.2 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 PVD25967.1 - 0.00099 19.2 0.8 1.3 9.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat MyTH4 PF00784.17 PVD25968.1 - 2.3e-31 108.5 1.2 1.7e-30 105.7 1.2 2.3 1 1 0 1 1 1 1 MyTH4 domain PH PF00169.29 PVD25968.1 - 4.9e-26 91.3 0.3 1.1e-15 58.0 0.2 3.1 3 0 0 3 3 2 2 PH domain PH_11 PF15413.6 PVD25968.1 - 5.6e-09 36.4 1.5 2.2e-06 28.1 0.6 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PVD25968.1 - 1.9e-07 31.1 1.1 3.6e-06 27.0 0.2 2.9 2 1 1 3 3 3 1 PH domain PH_8 PF15409.6 PVD25968.1 - 0.00017 21.8 0.1 0.00054 20.2 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain FERM_M PF00373.18 PVD25968.1 - 0.00033 21.1 0.4 0.0013 19.2 0.0 2.1 2 0 0 2 2 2 1 FERM central domain PH_15 PF17339.2 PVD25968.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_6 PF15406.6 PVD25968.1 - 0.072 13.4 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain ADIP PF11559.8 PVD25968.1 - 0.44 10.6 13.6 0.046 13.8 7.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 PVD25968.1 - 2.1 7.6 9.9 0.22 10.9 4.9 1.8 2 0 0 2 2 2 0 FAM76 protein DUF3552 PF12072.8 PVD25968.1 - 2.3 7.6 10.4 5.3 6.4 10.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FERM_M PF00373.18 PVD25969.1 - 0.00016 22.1 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 FERM central domain SERTA PF06031.13 PVD25971.1 - 2.8e-13 49.3 1.1 6e-13 48.2 1.1 1.6 1 0 0 1 1 1 1 SERTA motif Rossmann-like PF10727.9 PVD25972.1 - 0.029 14.2 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Rossmann-like domain CstA PF02554.14 PVD25972.1 - 0.17 10.7 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA Methyltransf_11 PF08241.12 PVD25973.1 - 2.3e-10 41.0 0.1 7.6e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD25973.1 - 4.6e-06 27.2 0.1 1.5e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD25973.1 - 0.0044 16.9 0.0 0.47 10.3 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PVD25973.1 - 0.02 15.6 0.1 0.15 12.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF1858 PF08984.11 PVD25973.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) RasGEF PF00617.19 PVD25974.1 - 7.2e-48 163.1 0.0 1.6e-47 162.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PVD25974.1 - 1.6e-31 108.6 0.2 3.9e-31 107.4 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 PVD25974.1 - 3e-15 56.9 0.4 1.6e-14 54.6 0.0 2.4 2 0 0 2 2 2 1 RhoGEF domain Histone PF00125.24 PVD25974.1 - 1.8e-10 41.3 0.0 4.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH PF00169.29 PVD25974.1 - 5.6e-08 33.2 0.0 2e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 PVD25974.1 - 0.011 15.7 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 PH domain CM_2 PF01817.21 PVD25974.1 - 0.13 12.6 1.5 7 7.1 0.4 3.4 2 1 0 2 2 2 0 Chorismate mutase type II PH_10 PF15411.6 PVD25974.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Aida_C2 PF14186.6 PVD25975.1 - 2.4e-59 199.2 0.0 3.3e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 PVD25975.1 - 1.4e-21 76.8 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Aida N-terminus G6PD_bact PF10786.9 PVD25975.1 - 0.051 13.1 0.2 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) RHD_DNA_bind PF00554.22 PVD25976.1 - 5.4e-68 228.2 0.6 1e-67 227.3 0.6 1.5 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 PVD25976.1 - 5.9e-39 132.2 0.0 1e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain Glycos_transf_2 PF00535.26 PVD25977.1 - 1.7e-33 115.8 0.0 2.4e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD25977.1 - 7.1e-17 61.8 1.3 1.3e-16 61.1 1.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 PVD25977.1 - 3.3e-09 36.6 0.0 4.2e-08 33.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 PVD25977.1 - 1.8e-07 31.3 0.0 3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD25977.1 - 4.9e-07 29.3 0.3 1.2e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 PVD25977.1 - 0.085 12.4 0.1 7.1 6.2 0.1 2.8 1 1 2 3 3 3 0 Cytolethal distending toxin A/C domain Glycos_transf_2 PF00535.26 PVD25978.1 - 6.6e-34 117.2 0.0 1.1e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD25978.1 - 2.6e-10 40.6 0.3 5.1e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 PVD25978.1 - 2.7e-09 36.9 0.0 6.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Acetyltransf_1 PF00583.25 PVD25978.1 - 5.1e-07 29.9 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_transf_7C PF02709.14 PVD25978.1 - 1.7e-06 27.5 0.2 4.6e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PVD25978.1 - 2e-06 27.8 0.0 7e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Acetyltransf_10 PF13673.7 PVD25978.1 - 0.016 15.1 0.0 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Adenylsucc_synt PF00709.21 PVD25979.1 - 3.3e-174 579.7 0.0 3.7e-174 579.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase GRIP PF01465.20 PVD25980.1 - 1.3e-15 57.0 0.1 5.4e-15 55.0 0.1 2.2 1 0 0 1 1 1 1 GRIP domain BRE1 PF08647.11 PVD25980.1 - 0.004 17.2 4.7 0.004 17.2 4.7 8.1 5 2 2 8 8 8 2 BRE1 E3 ubiquitin ligase DUF3258 PF11646.8 PVD25980.1 - 0.0048 17.0 0.8 0.025 14.7 0.8 2.2 1 0 0 1 1 1 1 Protein of unknown function DUF3258 APG6_N PF17675.1 PVD25980.1 - 0.047 14.2 0.2 0.047 14.2 0.2 7.4 2 1 3 6 6 6 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 PVD25980.1 - 1.3 8.5 102.2 0.019 14.5 17.0 6.6 3 1 3 6 6 6 0 Golgin subfamily A member 5 UAA PF08449.11 PVD25981.1 - 5.7e-67 226.1 28.4 7.5e-67 225.7 28.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PVD25981.1 - 0.00097 19.3 2.6 0.00097 19.3 2.6 3.4 4 1 0 4 4 4 2 EamA-like transporter family Exo84_C PF16528.5 PVD25981.1 - 0.022 14.6 1.3 0.037 13.8 1.3 1.3 1 0 0 1 1 1 0 Exocyst component 84 C-terminal TPT PF03151.16 PVD25981.1 - 0.041 13.2 18.4 0.16 11.3 18.4 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family PRORP PF16953.5 PVD25982.1 - 2.7e-62 210.5 0.4 4.5e-62 209.7 0.4 1.3 1 0 0 1 1 1 1 Protein-only RNase P RNase_Zc3h12a PF11977.8 PVD25982.1 - 1e-05 25.4 0.1 0.0001 22.1 0.1 2.3 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_long PF17177.4 PVD25982.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 PVD25982.1 - 0.0091 16.1 0.1 0.12 12.5 0.0 2.2 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 PVD25982.1 - 0.057 13.6 0.1 0.35 11.1 0.0 2.3 3 0 0 3 3 3 0 PPR repeat family BTB PF00651.31 PVD25983.1 - 5.5e-22 78.1 0.5 1.1e-21 77.1 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD25983.1 - 1.1e-08 35.0 1.8 2.4e-08 34.0 1.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 PVD25983.1 - 0.0061 16.7 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Ole-e-6 PF09253.10 PVD25983.1 - 0.085 12.8 1.1 0.22 11.5 1.1 1.6 1 0 0 1 1 1 0 Pollen allergen ole e 6 DUF2428 PF10350.9 PVD25984.1 - 7.2e-46 156.6 4.5 9.8e-43 146.4 4.5 2.6 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 PVD25984.1 - 0.021 15.2 0.1 3.4 8.1 0.0 4.1 4 0 0 4 4 4 0 HEAT repeats CBFD_NFYB_HMF PF00808.23 PVD25985.1 - 6.2e-14 52.0 0.8 8.3e-14 51.6 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PVD25985.1 - 7.4e-11 42.5 0.6 8.3e-11 42.4 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PVD25985.1 - 0.032 14.3 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold FERM_M PF00373.18 PVD25986.1 - 2.8e-17 63.2 0.0 6.6e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 PVD25986.1 - 4.1e-16 59.1 0.0 1.1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 PVD25986.1 - 1.3e-10 41.0 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Striatin PF08232.12 PVD25987.1 - 2.2e-50 171.2 1.1 2.2e-50 171.2 1.1 2.6 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 PVD25987.1 - 4.6e-36 122.2 10.0 1.7e-08 35.0 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD25987.1 - 2e-09 37.6 0.2 0.0036 17.6 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD25987.1 - 0.0053 15.5 2.5 1.7 7.2 0.7 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD25987.1 - 0.01 14.6 0.0 5.6 5.6 0.0 3.0 1 1 1 3 3 3 0 Nup133 N terminal like DUF4482 PF14818.6 PVD25987.1 - 0.2 12.6 8.1 0.19 12.6 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) SAM_1 PF00536.30 PVD25988.1 - 4.7e-07 30.2 0.7 1.2e-06 28.8 0.2 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 PVD25988.1 - 0.00092 19.0 0.0 1.9 8.3 0.0 3.2 4 0 0 4 4 4 2 PHAT DUF4508 PF14969.6 PVD25988.1 - 0.002 18.3 0.2 0.0064 16.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) SAM_2 PF07647.17 PVD25988.1 - 0.016 15.3 0.4 0.057 13.5 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Ribosom_S12_S23 PF00164.25 PVD25989.1 - 2.4e-24 85.1 0.1 3.4e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 PVD25990.1 - 1e-66 220.9 0.3 4.5e-26 90.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad51 PF08423.11 PVD25991.1 - 1.6e-14 53.8 0.0 2.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PVD25991.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PVD25991.1 - 0.0027 17.1 0.2 0.004 16.5 0.2 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 PVD25991.1 - 0.11 12.0 0.6 0.35 10.3 0.3 1.8 1 1 1 2 2 2 0 recA bacterial DNA recombination protein Pkinase PF00069.25 PVD25992.1 - 7.5e-76 255.0 0.0 1.1e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD25992.1 - 4.7e-44 150.6 0.0 7.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 PVD25992.1 - 5.9e-20 70.8 0.0 1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 PVD25992.1 - 1.9e-06 27.4 0.0 5.8e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 PVD25992.1 - 0.00035 20.2 0.3 0.00072 19.2 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PVD25992.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD25992.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain UBA PF00627.31 PVD25992.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain UBA_2 PF08587.11 PVD25992.1 - 0.035 14.2 0.3 0.091 12.9 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YrbL-PhoP_reg PF10707.9 PVD25992.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RNase_PH PF01138.21 PVD25993.1 - 8.4e-31 107.2 0.4 4.6e-15 56.3 0.0 4.0 3 1 1 4 4 4 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PVD25993.1 - 2.8e-14 52.9 0.1 1.4e-09 37.9 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 PVD25993.1 - 5.8e-10 39.5 1.9 8.9e-10 38.9 0.7 2.1 2 0 0 2 2 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 PVD25993.1 - 3.2e-05 24.2 0.4 0.00051 20.3 0.2 2.6 2 0 0 2 2 2 1 S1 RNA binding domain Syntaxin-5_N PF11416.8 PVD25993.1 - 0.00011 21.4 0.1 0.0003 19.9 0.1 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 PVD25993.1 - 0.00055 19.7 17.6 0.06 13.0 0.8 3.5 2 1 0 3 3 3 2 Syntaxin KH_1 PF00013.29 PVD25993.1 - 0.00067 19.4 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 KH domain DUF2316 PF10078.9 PVD25993.1 - 0.014 15.6 1.7 11 6.3 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) SF-assemblin PF06705.11 PVD25993.1 - 0.049 13.0 8.0 0.14 11.4 3.0 2.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF16 PF01519.16 PVD25993.1 - 1.6 9.2 8.4 1.5 9.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 PVD25993.1 - 4.9 7.7 9.5 6.2 7.4 2.0 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LIM PF00412.22 PVD25994.1 - 8.6e-25 86.7 24.6 9.8e-13 48.1 8.3 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 PVD25994.1 - 6.8e-06 25.6 15.7 0.9 9.2 0.1 4.8 4 0 0 4 4 4 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD25994.1 - 0.012 15.8 25.3 1.4 9.1 0.3 4.5 4 0 0 4 4 4 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 PVD25994.1 - 0.028 14.3 2.6 0.028 14.3 2.6 3.7 2 2 2 4 4 4 0 Putative transposase DNA-binding domain DNA_ligase_ZBD PF03119.16 PVD25994.1 - 0.031 14.3 2.4 2.5 8.2 0.4 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Mss51 PF13824.6 PVD25994.1 - 0.038 14.1 0.7 0.038 14.1 0.7 3.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ACC PF17848.1 PVD25994.1 - 0.062 13.4 13.7 0.42 10.7 0.3 3.8 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DUF637 PF04830.13 PVD25994.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) SelR PF01641.18 PVD25994.1 - 0.14 12.2 7.5 1.9 8.6 1.1 2.3 2 0 0 2 2 2 0 SelR domain zinc_ribbon_2 PF13240.6 PVD25994.1 - 0.32 10.8 30.1 0.73 9.6 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain DZR PF12773.7 PVD25994.1 - 0.4 10.7 25.0 9.1 6.4 8.8 4.3 2 2 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 PVD25994.1 - 0.82 9.6 10.3 3.7 7.5 0.3 3.7 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-CCHC_5 PF14787.6 PVD25994.1 - 1.3 8.8 10.5 2.1 8.1 0.1 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger MqsA_antitoxin PF15731.5 PVD25994.1 - 1.5 8.9 5.8 13 5.9 0.1 3.0 2 2 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF2616 PF11077.8 PVD25994.1 - 6.6 6.4 9.5 5.2 6.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) TF_Zn_Ribbon PF08271.12 PVD25994.1 - 8.1 6.0 23.4 1.2 8.8 0.3 4.7 4 1 0 4 4 4 0 TFIIB zinc-binding Sgf11 PF08209.11 PVD25994.1 - 9.1 5.9 16.2 11 5.7 2.0 4.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) DUF5521 PF17659.1 PVD25995.1 - 1e-49 169.2 0.1 1.3e-49 168.9 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF4539 PF15072.6 PVD25995.1 - 0.034 14.2 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) zf-C2HC_2 PF13913.6 PVD25996.1 - 4.4e-18 64.7 7.7 9.5e-09 34.9 1.5 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 PVD25996.1 - 0.017 15.9 5.5 0.59 11.1 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.11 PVD25996.1 - 0.03 13.9 5.0 0.49 10.0 0.7 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 PVD25996.1 - 0.033 13.8 0.3 10 5.8 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 PVD25996.1 - 0.2 12.0 2.7 2.7 8.4 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 PVD25996.1 - 0.23 12.0 1.4 3.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 PVD25996.1 - 0.61 10.2 2.4 6 7.1 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 PVD25996.1 - 4.6 7.8 5.0 10 6.8 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain DNA_mis_repair PF01119.19 PVD25997.1 - 1.8e-13 50.2 0.1 3.5e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 PVD25997.1 - 7.9e-10 38.7 0.0 5.2e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 PVD25997.1 - 1.6e-08 35.0 0.0 4.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PVD25997.1 - 7.7e-05 22.5 0.0 0.00022 21.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cnl2_NKP2 PF09447.10 PVD25997.1 - 0.14 12.3 0.2 0.48 10.6 0.2 1.9 1 0 0 1 1 1 0 Cnl2/NKP2 family protein DUF1748 PF08520.10 PVD25998.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) 7tm_1 PF00001.21 PVD26000.1 - 0.015 14.6 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Toxin_37 PF11415.8 PVD26000.1 - 0.093 12.6 3.4 0.16 11.8 3.4 1.4 1 0 0 1 1 1 0 Antifungal peptide termicin S1 PF00575.23 PVD26001.1 - 7e-18 64.8 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 PVD26001.1 - 1.3e-15 57.5 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 PVD26001.1 - 4.5e-05 23.7 0.0 7.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 TTL PF03133.15 PVD26002.1 - 2.6e-91 305.8 0.1 5.2e-91 304.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD26002.1 - 1.4e-06 27.8 0.1 0.0097 15.2 0.0 3.4 3 0 0 3 3 3 2 YheC/D like ATP-grasp Spec3 PF15795.5 PVD26003.1 - 1.1e-05 25.8 0.3 2e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein RRM_5 PF13893.6 PVD26004.1 - 4e-53 178.3 0.2 1.9e-40 137.3 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PVD26004.1 - 3e-27 94.3 0.2 1.1e-07 31.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PVD26004.1 - 2.2e-11 43.8 0.0 7.5e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 PVD26004.1 - 9.1e-07 28.7 0.0 0.21 11.5 0.0 3.8 4 0 0 4 4 4 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PVD26004.1 - 9.7e-06 25.6 0.3 0.0088 16.1 0.0 3.4 4 0 0 4 4 4 2 Limkain b1 RL PF17797.1 PVD26004.1 - 0.00041 20.2 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 1 RL domain RRM_3 PF08777.11 PVD26004.1 - 0.00066 19.7 0.0 1.3 9.1 0.0 3.5 4 0 0 4 4 4 1 RNA binding motif DUF4523 PF15023.6 PVD26004.1 - 0.071 12.9 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Aldose_epim PF01263.20 PVD26005.1 - 1.3e-72 244.6 0.0 7.5e-71 238.9 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase TetR_C_33 PF13305.6 PVD26006.1 - 0.26 12.0 1.9 0.85 10.4 1.9 2.0 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Kazal_2 PF07648.15 PVD26007.1 - 1e-19 70.4 18.9 1.1e-10 41.5 5.0 3.2 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD26007.1 - 7.6e-15 54.7 16.5 7e-09 35.6 5.0 2.6 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain CDC45 PF02724.14 PVD26007.1 - 0.0023 16.3 12.1 0.0028 16.0 12.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Spt5_N PF11942.8 PVD26007.1 - 4.3 8.4 18.9 8.9 7.4 18.9 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal U79_P34 PF03064.16 PVD26007.1 - 5.2 6.3 16.1 9 5.6 16.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 IGFBP PF00219.18 PVD26009.1 - 0.00091 19.8 14.3 0.0014 19.3 14.3 1.2 1 0 0 1 1 1 1 Insulin-like growth factor binding protein HAT PF02184.16 PVD26010.1 - 1e-32 111.7 68.1 9.9e-12 44.6 1.3 14.4 14 2 0 14 14 14 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 PVD26010.1 - 4.3e-13 48.9 18.4 0.31 12.0 0.3 10.9 5 4 7 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26010.1 - 1.7e-12 47.7 0.0 0.17 12.4 0.0 6.5 5 2 0 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 PVD26010.1 - 3.7e-09 37.0 45.6 0.00014 22.0 4.5 6.1 3 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 PVD26010.1 - 5.4e-09 35.8 0.2 7.3e-05 22.9 0.0 4.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26010.1 - 0.00021 21.2 5.7 16 6.0 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD26010.1 - 0.0017 18.4 30.2 1.1 9.2 1.2 6.6 3 3 1 5 5 5 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 PVD26010.1 - 0.0084 16.1 18.3 4.9 7.5 0.1 8.4 11 0 0 11 11 11 2 Tetratricopeptide repeat MuF_C PF18819.1 PVD26010.1 - 0.033 14.2 2.2 5.6 7.0 0.1 3.6 3 0 0 3 3 3 0 Phage MuF-C-terminal domain U3_assoc_6 PF08640.11 PVD26010.1 - 0.039 14.0 0.6 0.039 14.0 0.6 7.2 5 4 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Imm49 PF15575.6 PVD26010.1 - 0.12 12.1 11.1 0.043 13.6 3.5 2.8 3 0 0 3 3 3 0 Immunity protein 49 TPR_12 PF13424.6 PVD26010.1 - 0.62 10.4 13.8 1.6 9.0 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD26010.1 - 1.8 8.8 7.5 46 4.3 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF4821 PF16092.5 PVD26011.1 - 6.2e-101 337.4 0.0 6.8e-92 307.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 PVD26011.1 - 0.00017 21.0 0.0 0.064 12.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_10 PF13673.7 PVD26011.1 - 0.11 12.5 0.1 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Met_synt_B12 PF02965.17 PVD26012.1 - 5.2e-99 331.1 0.1 2.8e-98 328.7 0.1 2.1 1 1 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 PVD26012.1 - 3e-63 214.2 0.0 5.7e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 PVD26012.1 - 2.1e-51 175.0 1.6 8.9e-51 172.9 0.1 2.7 4 0 0 4 4 4 1 Pterin binding enzyme B12-binding_2 PF02607.17 PVD26012.1 - 1.3e-24 86.4 0.0 4e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 PVD26012.1 - 9e-20 70.9 1.5 2.8e-19 69.3 0.6 2.3 3 1 1 4 4 4 1 B12 binding domain BtpA PF03437.15 PVD26012.1 - 0.024 14.1 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 BtpA family Cys_rich_CPCC PF14206.6 PVD26012.1 - 0.13 12.1 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Cysteine-rich CPCC C1q PF00386.21 PVD26013.1 - 3.6e-13 49.8 2.1 5.8e-13 49.2 2.1 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD26013.1 - 0.001 19.0 7.8 0.0025 17.7 7.8 1.6 1 0 0 1 1 1 1 BclA C-terminal domain ig PF00047.25 PVD26013.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain SH3_2 PF07653.17 PVD26014.1 - 5.1e-08 32.5 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD26014.1 - 3.7e-05 23.5 0.0 9.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Filament PF00038.21 PVD26014.1 - 9.4e-05 22.1 29.7 9.4e-05 22.1 29.7 4.4 2 1 1 3 3 3 1 Intermediate filament protein SH3_1 PF00018.28 PVD26014.1 - 0.00025 20.6 0.0 0.00072 19.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SID-1_RNA_chan PF13965.6 PVD26014.1 - 4.4 5.6 4.0 11 4.3 4.0 1.7 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sfi1_C PF10638.9 PVD26014.1 - 5 7.9 9.1 31 5.4 4.9 3.6 2 0 0 2 2 2 0 Spindle body associated protein C-terminus Homeodomain PF00046.29 PVD26015.1 - 1.6e-18 66.3 5.7 2.7e-18 65.5 5.7 1.4 1 0 0 1 1 1 1 Homeodomain CDC45 PF02724.14 PVD26015.1 - 0.096 11.0 4.7 0.15 10.3 4.7 1.3 1 0 0 1 1 1 0 CDC45-like protein TraT PF05818.12 PVD26015.1 - 1.7 8.3 3.8 0.44 10.2 0.3 1.7 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein CCDC106 PF15794.5 PVD26015.1 - 6.2 6.5 8.7 10 5.8 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 E1_DerP2_DerF2 PF02221.15 PVD26016.1 - 1.1e-19 71.2 0.4 1.8e-19 70.5 0.4 1.4 1 0 0 1 1 1 1 ML domain Lipocalin PF00061.23 PVD26016.1 - 3.1e-10 40.4 0.1 4.4e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 PVD26016.1 - 0.0029 17.5 0.8 0.0075 16.2 0.7 1.7 2 1 0 2 2 2 1 Lipocalin-like domain E1_DerP2_DerF2 PF02221.15 PVD26017.1 - 4.4e-37 127.5 8.2 3e-23 82.7 2.4 2.1 1 1 1 2 2 2 2 ML domain Dak1 PF02733.17 PVD26018.1 - 2.4e-101 338.7 0.8 2.4e-101 338.7 0.8 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 PVD26018.1 - 8.1e-44 149.6 7.1 1.8e-43 148.5 7.1 1.6 1 0 0 1 1 1 1 DAK2 domain E1_DerP2_DerF2 PF02221.15 PVD26018.1 - 4.1e-18 66.1 0.2 7.3e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 ML domain RecX PF02631.16 PVD26018.1 - 0.051 14.0 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RecX family Dak1 PF02733.17 PVD26019.1 - 7.8e-85 284.5 4.0 3.9e-54 183.6 1.3 2.1 1 1 1 2 2 2 2 Dak1 domain Dak2 PF02734.17 PVD26019.1 - 9.9e-45 152.5 2.0 1e-44 152.5 0.4 1.8 2 1 0 2 2 2 1 DAK2 domain GFO_IDH_MocA PF01408.22 PVD26020.1 - 2.5e-19 70.3 0.0 1.6e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD26020.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PLDc_3 PF13918.6 PVD26021.1 - 4.6e-29 101.3 0.4 7.6e-29 100.6 0.4 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 PVD26021.1 - 7.9e-19 67.9 0.9 3.1e-15 56.3 0.1 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 PVD26021.1 - 2.4e-11 43.3 3.6 9.5e-09 35.1 0.4 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif TPR_12 PF13424.6 PVD26022.1 - 1.8e-09 37.7 3.6 0.00026 21.2 0.2 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26022.1 - 7.6e-08 31.9 4.2 0.027 14.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD26022.1 - 8.8e-08 31.8 1.2 0.052 13.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD26022.1 - 1.5e-06 27.8 5.7 0.0078 16.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26022.1 - 3.4e-05 23.6 1.1 0.071 13.2 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26022.1 - 0.0019 18.2 3.6 3.4 8.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD26022.1 - 0.44 10.8 3.5 1.2 9.4 0.3 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PVD26022.1 - 0.7 10.7 3.6 7.4 7.4 0.1 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 PVD26024.1 - 2.1e-10 41.3 0.1 3.8e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MIT PF04212.18 PVD26024.1 - 0.0015 18.5 1.0 0.003 17.6 1.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain 2OG-FeII_Oxy_5 PF13759.6 PVD26024.1 - 0.018 15.5 0.2 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TPR_11 PF13414.6 PVD26024.1 - 0.31 10.8 1.0 0.68 9.7 0.1 2.0 2 0 0 2 2 2 0 TPR repeat Myb_DNA-binding PF00249.31 PVD26025.1 - 1.9e-09 37.5 0.0 1.9e-09 37.5 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD26025.1 - 6.3e-05 23.1 3.8 6.6e-05 23.1 0.0 3.0 4 0 0 4 4 4 1 Myb-like DNA-binding domain SWIRM PF04433.17 PVD26025.1 - 8.5e-05 22.8 0.0 0.00032 21.0 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain DUF2207 PF09972.9 PVD26025.1 - 1.3 7.7 4.6 1.9 7.1 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAS_11 PF14598.6 PVD26026.1 - 3.4e-16 59.4 1.7 6.3e-16 58.5 0.8 2.0 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 PVD26026.1 - 7.1e-10 39.0 0.0 2.3e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 PVD26026.1 - 0.087 12.8 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 PAS fold ABC_tran PF00005.27 PVD26028.1 - 2.3e-18 67.0 0.0 3.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 PVD26028.1 - 1.8e-11 44.0 0.1 2.5e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_16 PF13191.6 PVD26028.1 - 0.0014 19.1 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PVD26028.1 - 0.0039 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD26028.1 - 0.0082 15.9 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 PVD26028.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 PVD26028.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IIGP PF05049.13 PVD26028.1 - 0.052 12.6 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 PVD26028.1 - 0.053 13.2 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PVD26028.1 - 0.06 13.6 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 PVD26028.1 - 0.07 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 PVD26028.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 PVD26028.1 - 0.087 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD26028.1 - 0.12 11.9 0.1 0.34 10.4 0.1 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 PVD26028.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PRK PF00485.18 PVD26028.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 PVD26028.1 - 0.18 11.0 0.1 0.78 9.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 PVD26028.1 - 0.18 12.3 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 PVD26028.1 - 0.21 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF4187 PF13821.6 PVD26029.1 - 4.5e-20 71.2 5.1 1.1e-19 69.9 5.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 PVD26029.1 - 6.1e-14 51.6 0.2 1.3e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD26029.1 - 4.3e-07 29.9 4.1 9e-07 28.9 0.3 2.6 1 1 1 2 2 2 1 G-patch domain NINJA_B PF16136.5 PVD26029.1 - 0.0054 17.1 3.2 0.0054 17.1 3.2 2.6 3 0 0 3 3 3 1 Putative nuclear localisation signal Presenilin PF01080.17 PVD26029.1 - 0.54 9.0 6.0 0.71 8.6 6.0 1.3 1 0 0 1 1 1 0 Presenilin zf-C2H2_3rep PF18868.1 PVD26029.1 - 5.7 7.6 7.1 1.6 9.4 0.1 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2052 PF09747.9 PVD26030.1 - 1.9e-41 142.4 30.1 1.9e-41 142.4 30.1 2.7 3 1 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) Connexin PF00029.19 PVD26030.1 - 0.83 9.4 3.2 1.6 8.5 3.2 1.5 1 0 0 1 1 1 0 Connexin DUF1115 PF06544.12 PVD26030.1 - 2.8 8.0 6.9 1.5 8.9 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) zf-C4 PF00105.18 PVD26031.1 - 8e-42 141.5 35.5 6.9e-25 87.3 12.4 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) MCM PF00493.23 PVD26032.1 - 8.1e-62 208.2 0.1 1.6e-61 207.3 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 PVD26032.1 - 8.5e-29 99.8 2.6 3.4e-28 97.9 1.2 2.6 3 0 0 3 3 3 1 MCM AAA-lid domain TAP_C PF03943.13 PVD26032.1 - 7.8e-22 76.7 0.3 1.8e-21 75.5 0.3 1.7 1 0 0 1 1 1 1 TAP C-terminal domain Tap-RNA_bind PF09162.10 PVD26032.1 - 8.3e-21 73.6 0.0 1.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Tap, RNA-binding NTF2 PF02136.20 PVD26032.1 - 1.1e-08 35.6 0.8 2.2e-07 31.4 0.8 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mg_chelatase PF01078.21 PVD26032.1 - 5.2e-07 29.3 0.0 9.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI LRR_9 PF14580.6 PVD26032.1 - 0.003 17.1 0.5 0.0063 16.0 0.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PVD26032.1 - 0.0034 17.8 11.1 0.005 17.2 8.8 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) AAA_3 PF07726.11 PVD26032.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LRR_8 PF13855.6 PVD26032.1 - 0.065 13.0 8.7 0.25 11.2 8.6 2.1 1 1 0 1 1 1 0 Leucine rich repeat DUF4764 PF15961.5 PVD26033.1 - 1.5e-53 182.7 15.9 1.5e-53 182.7 15.9 4.1 2 2 0 3 3 3 1 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 PVD26033.1 - 0.91 10.1 3.0 0.43 11.1 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type PfkB PF00294.24 PVD26034.1 - 2.3e-49 168.3 1.2 2.6e-49 168.2 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PVD26034.1 - 1.4e-09 37.8 0.2 3.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase bZIP_2 PF07716.15 PVD26035.1 - 2.1e-15 56.5 13.1 5e-15 55.3 13.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper SR-25 PF10500.9 PVD26035.1 - 5e-05 23.0 13.3 8.8e-05 22.2 13.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.21 PVD26035.1 - 0.0004 20.4 9.2 0.0004 20.4 9.2 1.7 2 0 0 2 2 2 1 bZIP transcription factor IMUP PF15761.5 PVD26035.1 - 0.0021 18.7 7.1 0.0021 18.7 7.1 2.0 2 0 0 2 2 2 1 Immortalisation up-regulated protein SOBP PF15279.6 PVD26035.1 - 0.047 14.3 6.8 0.062 13.9 3.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein tRNA_anti-like PF12869.7 PVD26035.1 - 0.082 12.5 0.8 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 tRNA_anti-like bZIP_Maf PF03131.17 PVD26035.1 - 0.35 11.4 12.7 0.059 13.9 6.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Hid1 PF12722.7 PVD26035.1 - 3 5.9 8.1 3.7 5.5 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAML PF14963.6 PVD26035.1 - 6.9 6.7 8.5 11 6.0 8.5 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Proteasome PF00227.26 PVD26036.1 - 1.3e-40 138.9 0.0 2.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 PVD26037.1 - 1.2e-55 187.9 0.1 1.2e-55 187.9 0.1 1.3 2 0 0 2 2 2 1 Proteasome subunit LRR_6 PF13516.6 PVD26038.1 - 1.3e-22 77.8 18.5 0.0039 17.1 0.0 9.2 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 PVD26038.1 - 1.1e-09 37.5 0.2 3.7 8.5 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 PVD26038.1 - 1.3e-05 25.4 8.6 0.013 15.9 0.2 5.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD26038.1 - 0.0003 20.5 13.9 0.0027 17.4 1.9 5.0 3 2 2 5 5 5 3 Leucine rich repeat GTP_EFTU PF00009.27 PVD26039.1 - 6.2e-64 215.1 0.0 9.5e-64 214.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 PVD26039.1 - 1.2e-10 41.4 0.1 2.9e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PVD26039.1 - 2.2e-09 37.5 0.1 4.2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PVD26039.1 - 0.00042 20.4 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD26039.1 - 0.0056 16.2 0.1 0.04 13.5 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B EFG_IV PF03764.18 PVD26039.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV AvrPtoB_bdg PF16847.5 PVD26039.1 - 0.023 15.2 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.16 PVD26039.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family NRDE-2 PF08424.10 PVD26040.1 - 4.2e-90 302.1 1.5 4.2e-90 302.1 1.5 3.1 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 PVD26040.1 - 1.9e-08 34.4 0.2 0.14 13.1 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF1818 PF08848.11 PVD26040.1 - 0.12 12.4 1.2 5.8 7.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1818) Draxin PF15550.6 PVD26040.1 - 0.22 11.4 10.8 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Draxin STAT_bind PF02864.15 PVD26040.1 - 0.37 11.3 3.2 0.77 10.3 0.0 2.7 2 0 0 2 2 2 0 STAT protein, DNA binding domain ADP_PFK_GK PF04587.15 PVD26041.1 - 6.8e-135 449.9 0.0 8.2e-135 449.6 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region VWC PF00093.18 PVD26042.1 - 1.3e-35 121.5 131.1 3.9e-09 36.7 15.1 13.3 8 2 4 12 12 12 6 von Willebrand factor type C domain Antistasin PF02822.14 PVD26042.1 - 1.8e-07 31.7 51.2 0.00013 22.5 8.9 15.7 17 2 0 17 17 17 4 Antistasin family TILa PF12714.7 PVD26042.1 - 5e-05 23.2 25.3 8.9e-05 22.4 5.7 12.5 11 2 2 13 13 13 6 TILa domain PSP94 PF05825.11 PVD26042.1 - 0.02 15.4 0.6 0.02 15.4 0.6 9.3 7 3 3 10 10 10 0 Beta-microseminoprotein (PSP-94) DAG1 PF05454.11 PVD26042.1 - 0.045 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) IGFBP PF00219.18 PVD26043.1 - 1.4e-10 41.7 18.4 2.2e-10 41.0 18.4 1.3 1 0 0 1 1 1 1 Insulin-like growth factor binding protein tRNA-synt_1g PF09334.11 PVD26044.1 - 0.069 11.9 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) PDDEXK_1 PF12705.7 PVD26045.1 - 4e-07 30.2 0.0 4.9e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily NinD PF17466.2 PVD26045.1 - 0.15 12.1 0.4 0.38 10.9 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function PYC_OADA PF02436.18 PVD26046.1 - 9.4e-71 237.7 0.0 1.9e-70 236.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_D2 PF02786.17 PVD26046.1 - 1.7e-61 207.4 0.0 2.8e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PVD26046.1 - 9.5e-42 142.0 0.0 2.3e-41 140.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 PVD26046.1 - 4.9e-32 111.5 0.0 1.6e-31 109.9 0.0 1.8 2 0 0 2 2 2 1 HMGL-like Biotin_carb_C PF02785.19 PVD26046.1 - 7.2e-32 109.7 0.0 1.9e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PVD26046.1 - 1.2e-18 66.7 5.3 1.2e-18 66.7 5.3 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PVD26046.1 - 3.4e-08 33.2 1.0 8.8e-05 22.3 0.6 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 PVD26046.1 - 2.1e-07 30.7 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus NQRA PF05896.11 PVD26046.1 - 1.9e-05 24.3 0.5 3.5e-05 23.4 0.5 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_3 PF13437.6 PVD26046.1 - 0.00032 21.4 0.3 0.0054 17.4 0.5 2.8 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 PVD26046.1 - 0.00071 19.5 0.3 0.0039 17.1 0.3 2.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 PVD26046.1 - 0.016 14.4 0.3 2.7 7.2 0.1 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 PVD26046.1 - 0.12 12.2 0.4 0.36 10.7 0.4 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein PTE PF02126.18 PVD26046.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotriesterase family DUF2515 PF10720.9 PVD26046.1 - 0.15 11.2 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) Rap_GAP PF02145.15 PVD26047.1 - 6.4e-42 143.2 0.0 1.3e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Kunitz_BPTI PF00014.23 PVD26047.1 - 1.5e-09 37.9 2.3 1.5e-09 37.9 2.3 1.9 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3572 PF12096.8 PVD26047.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) SIX1_SD PF16878.5 PVD26050.1 - 2.1e-47 160.2 0.5 1.6e-46 157.4 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 PVD26050.1 - 2.5e-12 46.4 3.8 3.4e-12 46.0 1.5 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PVD26050.1 - 1.5e-10 40.8 1.2 4.4e-10 39.3 1.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 PVD26050.1 - 0.036 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 PVD26050.1 - 0.081 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3439 PF11921.8 PVD26051.1 - 1.4 8.9 23.9 3.6 7.6 23.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MGC-24 PF05283.11 PVD26051.1 - 3.3 8.2 14.5 2.1 8.8 8.9 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin YhhN PF07947.14 PVD26053.1 - 5.2e-34 117.5 14.1 8.1e-34 116.8 14.1 1.3 1 0 0 1 1 1 1 YhhN family Pox_P21 PF05313.12 PVD26053.1 - 0.19 11.3 0.2 0.19 11.3 0.2 2.4 2 1 1 3 3 3 0 Poxvirus P21 membrane protein YhhN PF07947.14 PVD26054.1 - 5e-33 114.3 8.3 5e-33 114.3 8.3 1.4 2 0 0 2 2 2 1 YhhN family Nramp PF01566.18 PVD26054.1 - 0.02 13.9 2.3 0.067 12.1 0.9 2.0 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein Glyco_hydro_59M PF17387.2 PVD26055.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 59 central domain Med7 PF05983.11 PVD26058.1 - 0.058 13.5 0.3 0.058 13.5 0.3 1.1 1 0 0 1 1 1 0 MED7 protein SIX1_SD PF16878.5 PVD26064.1 - 2.3e-49 166.5 0.1 4.7e-49 165.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 PVD26064.1 - 1.5e-14 53.6 1.6 1.8e-14 53.3 0.5 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PVD26064.1 - 8.3e-13 48.0 1.1 1.8e-12 46.9 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 PVD26064.1 - 0.0064 15.9 0.1 0.018 14.5 0.1 1.7 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 PVD26064.1 - 0.0097 16.0 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix YdaS_antitoxin PF15943.5 PVD26064.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4746 PF15928.5 PVD26066.1 - 0.12 11.8 4.4 0.17 11.3 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 PVD26066.1 - 1.2 7.9 4.8 1.5 7.6 4.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VWA_2 PF13519.6 PVD26071.1 - 1.7e-08 35.1 0.0 7.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PVD26071.1 - 3.1e-08 34.1 0.0 6.9e-08 32.9 0.0 1.6 1 1 1 2 2 2 1 von Willebrand factor type A domain Med25_VWA PF11265.8 PVD26071.1 - 6e-05 23.0 0.0 0.00029 20.7 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 PVD26071.1 - 0.00052 19.8 0.0 0.0039 16.9 0.0 2.1 1 1 1 2 2 2 1 Integrin beta chain VWA domain DUF2610 PF11020.8 PVD26071.1 - 0.028 14.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) VWA_2 PF13519.6 PVD26072.1 - 6.9e-05 23.4 0.0 0.00022 21.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PVD26072.1 - 0.004 17.4 0.0 0.02 15.2 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain EnY2 PF10163.9 PVD26072.1 - 0.016 15.6 1.2 0.033 14.5 0.4 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 UPF0270 PF06794.12 PVD26072.1 - 0.28 11.3 1.5 8.1 6.6 0.1 3.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0270) PIRT PF15099.6 PVD26073.1 - 0.0027 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Phage_holin_3_6 PF07332.11 PVD26073.1 - 0.016 15.2 0.9 0.024 14.7 0.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_2_4 PF16082.5 PVD26073.1 - 0.26 11.1 1.4 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like YlaH PF14036.6 PVD26073.1 - 0.27 11.6 2.9 0.43 10.9 2.9 1.2 1 0 0 1 1 1 0 YlaH-like protein DUF2721 PF11026.8 PVD26073.1 - 0.95 9.4 4.0 1.5 8.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2892 PF11127.8 PVD26073.1 - 5.1 7.2 7.5 14 5.8 7.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) KxDL PF10241.9 PVD26074.1 - 6.5e-05 23.1 23.1 0.00086 19.5 4.9 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein Leu_zip PF15294.6 PVD26074.1 - 0.00011 21.8 10.9 0.00011 21.8 10.9 2.1 1 1 1 2 2 2 1 Leucine zipper ATG16 PF08614.11 PVD26074.1 - 0.00022 21.5 36.9 0.00046 20.5 13.9 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 PVD26074.1 - 0.0011 18.6 14.0 0.0017 18.0 14.0 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF1664 PF07889.12 PVD26074.1 - 0.0012 18.9 18.7 0.005 16.9 2.0 2.9 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD26074.1 - 0.0014 18.7 28.8 0.0092 16.0 10.9 2.6 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 PVD26074.1 - 0.0014 17.3 16.9 0.0019 17.0 16.9 1.1 1 0 0 1 1 1 1 AAA domain Fzo_mitofusin PF04799.13 PVD26074.1 - 0.0016 18.0 3.9 0.0016 18.0 3.9 2.3 1 1 1 2 2 2 1 fzo-like conserved region WEMBL PF05701.11 PVD26074.1 - 0.0035 16.1 17.1 0.006 15.3 17.1 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3584 PF12128.8 PVD26074.1 - 0.0053 14.3 20.1 0.0066 14.0 20.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ZapB PF06005.12 PVD26074.1 - 0.011 16.1 6.7 0.011 16.1 6.7 3.5 1 1 1 2 2 1 0 Cell division protein ZapB CALCOCO1 PF07888.11 PVD26074.1 - 0.013 14.4 32.9 0.017 14.0 32.1 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 PVD26074.1 - 0.013 14.8 15.9 0.021 14.2 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 PVD26074.1 - 0.014 15.7 0.7 0.014 15.7 0.7 4.3 1 1 3 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIP3 PF03915.13 PVD26074.1 - 0.015 14.4 15.5 0.021 14.0 15.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 APG6_N PF17675.1 PVD26074.1 - 0.016 15.7 27.1 0.016 15.7 27.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 PVD26074.1 - 0.018 15.4 27.9 0.059 13.7 23.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MAD PF05557.13 PVD26074.1 - 0.02 13.3 23.7 0.031 12.7 23.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 PVD26074.1 - 0.02 13.8 30.6 0.33 9.8 17.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4763 PF15960.5 PVD26074.1 - 0.021 14.1 31.1 0.047 13.0 21.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) DASH_Dam1 PF08653.10 PVD26074.1 - 0.026 14.3 8.5 0.67 9.8 0.2 3.6 3 1 0 4 4 3 0 DASH complex subunit Dam1 FPP PF05911.11 PVD26074.1 - 0.028 12.6 25.5 0.058 11.6 25.5 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 PVD26074.1 - 0.034 13.4 28.4 0.079 12.3 15.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 PVD26074.1 - 0.041 14.1 25.4 0.032 14.4 10.0 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 PVD26074.1 - 0.043 13.4 26.1 0.75 9.3 11.0 2.4 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.7 PVD26074.1 - 0.061 13.5 32.8 0.1 12.7 31.7 1.8 1 1 1 2 2 1 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 PVD26074.1 - 0.065 13.5 33.2 0.94 9.7 22.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 AAA_32 PF13654.6 PVD26074.1 - 0.072 11.9 17.3 0.12 11.1 17.3 1.3 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 PVD26074.1 - 0.074 13.4 23.6 0.1 12.9 9.1 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 PVD26074.1 - 0.077 12.9 16.7 0.11 12.3 7.2 2.7 2 1 1 3 3 2 0 Sec8 exocyst complex component specific domain Borrelia_P83 PF05262.11 PVD26074.1 - 0.086 11.3 14.6 0.11 11.0 14.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF812 PF05667.11 PVD26074.1 - 0.099 11.5 26.7 0.29 10.0 21.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 PVD26074.1 - 0.1 12.7 34.6 4.6 7.3 32.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 PVD26074.1 - 0.11 10.3 34.2 1.4 6.6 34.4 1.9 1 1 0 1 1 1 0 Myosin tail TMF_DNA_bd PF12329.8 PVD26074.1 - 0.12 12.4 33.7 0.92 9.6 15.4 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.14 PVD26074.1 - 0.13 12.0 26.6 0.046 13.4 12.3 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF4618 PF15397.6 PVD26074.1 - 0.14 11.5 24.1 0.26 10.7 21.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 PVD26074.1 - 0.14 11.6 26.1 0.24 10.8 26.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 FUSC PF04632.12 PVD26074.1 - 0.14 10.6 8.4 0.18 10.3 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.6 PVD26074.1 - 0.15 12.4 24.5 0.65 10.3 4.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ABC_tran_CTD PF16326.5 PVD26074.1 - 0.15 12.3 28.2 0.27 11.5 1.9 4.1 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF713 PF05218.14 PVD26074.1 - 0.16 11.7 12.1 1.2 8.8 12.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF713) DUF745 PF05335.13 PVD26074.1 - 0.17 11.6 17.4 0.31 10.7 17.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TRAF_BIRC3_bd PF16673.5 PVD26074.1 - 0.2 11.5 22.0 0.47 10.3 5.1 4.2 1 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain ADIP PF11559.8 PVD26074.1 - 0.22 11.6 33.0 0.25 11.4 7.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.20 PVD26074.1 - 0.3 10.4 27.0 0.72 9.2 27.0 1.5 1 1 0 1 1 1 0 Tropomyosin Mod_r PF07200.13 PVD26074.1 - 0.31 11.2 27.1 0.8 9.8 9.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF87 PF01935.17 PVD26074.1 - 0.32 11.0 7.5 0.45 10.6 7.5 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain PCRF PF03462.18 PVD26074.1 - 0.35 10.7 20.2 0.67 9.8 7.4 2.1 1 1 1 2 2 2 0 PCRF domain Syntaxin-6_N PF09177.11 PVD26074.1 - 0.35 11.5 18.7 0.21 12.2 3.8 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF5082 PF16888.5 PVD26074.1 - 0.38 11.0 22.5 1.2 9.4 21.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Phage_GPO PF05929.11 PVD26074.1 - 0.39 10.3 19.5 0.97 9.0 13.0 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 PVD26074.1 - 0.43 9.9 32.6 1.1 8.6 7.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 PVD26074.1 - 0.44 8.6 33.6 1.2 7.2 9.8 1.9 1 1 1 2 2 2 0 HOOK protein DUF4162 PF13732.6 PVD26074.1 - 0.45 11.3 5.5 1.1 10.1 5.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4162) DUF2868 PF11067.8 PVD26074.1 - 0.47 9.9 6.5 0.68 9.4 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) FlaC_arch PF05377.11 PVD26074.1 - 0.47 10.9 23.9 0.13 12.7 1.0 4.5 1 1 3 4 4 3 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 PVD26074.1 - 0.53 10.7 26.5 0.62 10.5 23.3 2.3 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 PVD26074.1 - 0.62 10.7 31.5 1.1 9.9 9.0 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HrpB7 PF09486.10 PVD26074.1 - 0.64 10.4 16.6 2.7 8.4 16.4 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.6 PVD26074.1 - 0.65 10.0 30.0 0.13 12.3 6.0 2.1 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.12 PVD26074.1 - 0.66 10.0 20.8 2 8.5 3.4 2.9 1 1 2 3 3 3 0 Laminin Domain II MscS_porin PF12795.7 PVD26074.1 - 0.69 9.4 34.0 0.16 11.5 22.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FliJ PF02050.16 PVD26074.1 - 0.71 10.1 27.4 7 6.9 7.5 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein V_ATPase_I PF01496.19 PVD26074.1 - 0.73 7.7 22.0 0.22 9.4 2.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family RmuC PF02646.16 PVD26074.1 - 0.76 8.9 19.1 0.19 10.8 3.3 2.2 1 1 1 2 2 2 0 RmuC family EzrA PF06160.12 PVD26074.1 - 0.79 7.8 23.7 11 4.1 23.8 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Syntaxin_2 PF14523.6 PVD26074.1 - 0.81 10.1 23.3 2.6 8.4 6.5 2.4 1 1 1 2 2 2 0 Syntaxin-like protein TACC_C PF05010.14 PVD26074.1 - 0.84 9.4 25.4 3.8 7.2 25.4 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-C4H2 PF10146.9 PVD26074.1 - 0.94 9.7 19.8 0.032 14.5 12.6 2.1 2 1 1 3 3 2 0 Zinc finger-containing protein CREPT PF16566.5 PVD26074.1 - 1.1 9.5 22.8 0.49 10.6 7.2 2.9 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF948 PF06103.11 PVD26074.1 - 1.2 9.5 13.0 2.3 8.5 1.5 2.8 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 PVD26074.1 - 1.2 8.8 23.3 3.2 7.4 23.4 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein TBCA PF02970.16 PVD26074.1 - 1.5 9.2 24.3 0.52 10.7 7.8 2.5 1 1 1 2 2 2 0 Tubulin binding cofactor A TMPIT PF07851.13 PVD26074.1 - 1.6 7.9 20.4 0.25 10.5 8.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein Lebercilin PF15619.6 PVD26074.1 - 1.7 8.3 36.3 0.58 9.8 29.3 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SKA1 PF07160.12 PVD26074.1 - 1.7 8.5 20.3 4.2 7.1 6.0 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Vps54_N PF10475.9 PVD26074.1 - 1.8 7.8 15.2 2.9 7.1 2.1 2.1 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Cauli_AT PF03233.13 PVD26074.1 - 1.9 8.4 15.8 2.2 8.2 3.8 2.3 1 1 1 2 2 2 0 Aphid transmission protein Atg14 PF10186.9 PVD26074.1 - 2 7.4 27.7 3.1 6.8 14.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 PVD26074.1 - 2.3 9.0 23.9 3.7 8.3 5.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) COG2 PF06148.11 PVD26074.1 - 2.3 8.3 17.9 3.5 7.7 8.3 3.1 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HemX PF04375.14 PVD26074.1 - 2.4 7.3 28.6 1.6 7.9 6.0 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4226 PF10774.9 PVD26074.1 - 2.4 8.4 12.8 0.48 10.7 0.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4226) TolA_bind_tri PF16331.5 PVD26074.1 - 2.5 8.2 35.8 0.6 10.2 8.9 2.6 1 1 0 2 2 2 0 TolA binding protein trimerisation T3SS_needle_E PF08988.10 PVD26074.1 - 2.6 8.2 13.5 2.3 8.4 3.0 3.1 1 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle IFT57 PF10498.9 PVD26074.1 - 2.7 6.9 26.4 0.69 8.8 7.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4200 PF13863.6 PVD26074.1 - 3 8.3 28.7 84 3.6 28.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-F_N PF10481.9 PVD26074.1 - 3.2 7.3 32.3 0.45 10.1 2.1 3.0 1 1 2 3 3 3 0 Cenp-F N-terminal domain YPEB PF14620.6 PVD26074.1 - 3.4 6.9 20.3 2.4 7.4 1.8 2.2 1 1 1 2 2 2 0 YpeB sporulation ERM PF00769.19 PVD26074.1 - 3.4 7.4 31.2 0.14 11.9 20.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family T3SSipB PF16535.5 PVD26074.1 - 3.5 8.1 16.1 0.12 12.9 5.5 2.3 1 1 2 3 3 3 0 Type III cell invasion protein SipB FapA PF03961.13 PVD26074.1 - 3.5 6.1 26.0 3.7 6.0 8.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A XRN_M PF17846.1 PVD26074.1 - 3.6 6.5 10.1 4.7 6.0 10.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain HSBP1 PF06825.12 PVD26074.1 - 4 7.4 20.8 0.89 9.5 0.6 4.7 3 1 1 5 5 4 0 Heat shock factor binding protein 1 TMF_TATA_bd PF12325.8 PVD26074.1 - 4.1 7.6 28.6 14 5.9 1.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FliD_N PF02465.18 PVD26074.1 - 4.2 8.1 20.0 69 4.2 9.6 3.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SHE3 PF17078.5 PVD26074.1 - 4.2 7.0 25.1 0.65 9.7 12.3 2.6 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 PVD26074.1 - 4.3 7.1 22.5 6.7 6.5 16.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 PVD26074.1 - 5.9 7.9 32.1 9.8 7.1 20.3 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain HAUS-augmin3 PF14932.6 PVD26074.1 - 5.9 6.4 27.2 0.55 9.8 12.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 PVD26074.1 - 6.2 7.4 18.5 1.5e+02 2.9 8.3 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 PVD26074.1 - 6.2 6.9 37.2 0.8 9.8 16.2 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Prominin PF05478.11 PVD26074.1 - 6.7 4.5 17.4 0.76 7.7 11.6 1.7 1 1 0 1 1 1 0 Prominin DUF4349 PF14257.6 PVD26074.1 - 7 6.0 22.7 80 2.6 22.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2203 PF09969.9 PVD26074.1 - 7.3 7.3 18.2 16 6.2 6.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) NPBW PF15180.6 PVD26074.1 - 7.4 6.5 7.0 1.9 8.4 2.0 2.4 2 2 1 3 3 2 0 Neuropeptides B and W Tup_N PF08581.10 PVD26074.1 - 7.9 6.9 23.3 5.9 7.3 5.2 2.9 1 1 2 3 3 3 0 Tup N-terminal GSDH PF07995.11 PVD26075.1 - 2.6e-26 92.7 0.5 1.2e-25 90.6 0.5 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase GSDH PF07995.11 PVD26076.1 - 3.1e-36 125.4 0.0 5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 PVD26076.1 - 4.8e-07 29.8 13.4 7.8e-07 29.1 13.4 1.4 1 0 0 1 1 1 1 Folate receptor family Colicin_V PF02674.16 PVD26079.1 - 0.032 14.2 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 Colicin V production protein ECSCR PF15820.5 PVD26079.1 - 0.23 11.3 4.8 0.17 11.7 0.5 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator Ras PF00071.22 PVD26080.1 - 8.9e-68 227.0 1.1 1e-67 226.8 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD26080.1 - 1.1e-37 128.9 0.9 1.7e-37 128.3 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD26080.1 - 1.1e-17 64.0 0.1 1.4e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD26080.1 - 3.2e-07 30.4 0.9 0.0044 17.0 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD26080.1 - 4.8e-06 26.3 0.4 1.2e-05 24.9 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD26080.1 - 6.2e-06 25.7 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD26080.1 - 1.5e-05 24.6 0.1 2.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD26080.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 PVD26080.1 - 0.0012 19.3 0.1 0.13 12.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 PVD26080.1 - 0.005 16.4 0.1 0.026 14.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 PVD26080.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 PVD26080.1 - 0.018 14.8 0.1 1 9.1 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PVD26080.1 - 0.038 14.3 0.1 0.089 13.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PVD26080.1 - 0.041 13.4 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 PVD26080.1 - 0.054 12.8 0.1 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Septin ABC_tran PF00005.27 PVD26080.1 - 0.061 13.8 0.0 0.097 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PVD26080.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 PVD26080.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 PVD26080.1 - 0.076 11.6 0.1 0.16 10.6 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein TniB PF05621.11 PVD26080.1 - 0.091 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 PVD26080.1 - 0.11 12.9 1.4 1 9.8 0.3 2.5 1 1 1 2 2 2 0 RNA helicase Dioxygenase_N PF04444.14 PVD26080.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Cadherin-like PF12733.7 PVD26081.1 - 2e-13 50.7 0.2 3.5e-11 43.5 0.3 2.7 2 0 0 2 2 2 1 Cadherin-like beta sandwich domain TPR_11 PF13414.6 PVD26081.1 - 7.8e-09 35.1 1.2 0.0021 17.7 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 PVD26081.1 - 8.8e-08 32.3 2.6 0.0025 18.5 0.0 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26081.1 - 1.4e-06 28.7 5.7 0.036 14.6 0.5 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD26081.1 - 1.5e-06 28.2 1.7 0.087 13.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26081.1 - 2.1e-06 27.4 1.6 0.075 13.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD26081.1 - 1.1e-05 25.9 0.6 0.16 12.6 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD26081.1 - 2.1e-05 24.7 0.2 0.68 10.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26081.1 - 0.011 15.7 0.2 12 6.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD26081.1 - 0.015 15.6 0.1 24 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26081.1 - 0.02 15.1 5.8 0.29 11.4 0.0 5.2 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD26081.1 - 0.025 15.2 3.0 1.4 9.7 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD26081.1 - 0.026 14.3 2.6 1.1 9.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD26081.1 - 0.11 12.7 0.0 34 4.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD26081.1 - 0.19 11.7 0.2 25 4.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 PVD26082.1 - 5.7e-42 143.5 0.6 8.9e-42 142.8 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 PVD26082.1 - 1.8e-16 60.9 0.1 2.9e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal APG12 PF04110.13 PVD26082.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Rad51 PF08423.11 PVD26083.1 - 2.3e-131 436.7 0.1 2.8e-131 436.4 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PVD26083.1 - 1.4e-10 41.1 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 PVD26083.1 - 5.7e-10 39.1 0.1 8.3e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 PVD26083.1 - 3.6e-09 37.1 0.7 1.5e-08 35.1 0.9 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 PVD26083.1 - 8.3e-07 28.6 1.5 7.5e-06 25.5 1.5 2.2 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 PVD26083.1 - 0.0079 15.6 0.4 3.5 6.9 0.0 2.3 1 1 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_22 PF13401.6 PVD26083.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PVD26083.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PVD26083.1 - 0.047 13.9 1.3 0.048 13.9 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PVD26083.1 - 0.058 13.8 0.0 0.41 11.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HHH PF00633.23 PVD26083.1 - 0.076 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PI-PLC-X PF00388.19 PVD26084.1 - 5.9e-61 204.3 1.6 1.1e-60 203.4 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PVD26084.1 - 1.6e-41 141.3 0.4 1.6e-41 141.3 0.4 3.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 PVD26084.1 - 5.6e-38 129.8 0.2 1.5e-37 128.4 0.0 1.9 2 0 0 2 2 2 1 PH domain DUF1154 PF06631.11 PVD26084.1 - 5.3e-14 52.0 9.3 5.3e-14 52.0 9.3 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 PVD26084.1 - 1.9e-10 41.1 0.1 1.9e-10 41.1 0.1 3.3 4 0 0 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 PVD26084.1 - 1.5e-07 31.6 0.0 4.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain RNA_pol_A_bac PF01000.26 PVD26085.1 - 6.6e-29 100.5 0.0 1.7e-28 99.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PVD26085.1 - 4.2e-12 45.3 0.0 6.4e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MCLC PF05934.11 PVD26087.1 - 1.6 7.4 10.2 1.8 7.2 10.2 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) I-set PF07679.16 PVD26089.1 - 2.2e-80 264.8 0.0 3.1e-16 59.2 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26089.1 - 6.2e-79 260.6 0.0 1.6e-16 60.7 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase_Tyr PF07714.17 PVD26089.1 - 5.8e-62 209.3 0.0 9.7e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 PVD26089.1 - 4.1e-58 193.7 0.2 5.8e-11 42.6 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 PVD26089.1 - 8.7e-43 144.4 0.1 1.5e-09 37.9 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Pkinase PF00069.25 PVD26089.1 - 5.5e-29 101.3 0.0 8.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 PVD26089.1 - 8.3e-29 100.0 4.9 0.0068 16.6 0.0 10.2 7 3 1 8 8 8 7 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD26089.1 - 1.5e-16 59.6 0.0 9.3e-05 21.9 0.0 7.3 7 0 0 7 7 7 3 Immunoglobulin domain C2-set_2 PF08205.12 PVD26089.1 - 2.8e-12 46.5 0.7 0.12 12.4 0.0 6.2 7 0 0 7 7 6 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD26089.1 - 2.7e-08 34.1 0.3 4 7.9 0.0 6.3 6 1 0 6 6 6 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 PVD26089.1 - 6.5e-08 32.7 0.0 0.44 10.9 0.0 6.2 6 0 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD26089.1 - 6.7e-08 32.8 0.0 2.6 8.5 0.0 6.4 7 1 0 7 7 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD26089.1 - 1.5e-05 24.9 0.0 3.4 7.8 0.0 5.7 7 0 0 7 7 7 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD26089.1 - 0.00029 21.0 0.0 12 6.2 0.0 4.8 4 1 1 5 5 5 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 PVD26089.1 - 0.073 12.9 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 Kdo PF06293.14 PVD26089.1 - 0.19 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C4 PF00105.18 PVD26090.1 - 2.5e-41 140.0 39.8 5.7e-24 84.4 10.7 3.3 3 0 0 3 3 3 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD26090.1 - 6.4e-14 52.0 1.7 1.5e-13 50.8 1.7 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C2H2_jaz PF12171.8 PVD26090.1 - 3.8 7.9 8.4 0.35 11.2 1.5 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Beach PF02138.18 PVD26091.1 - 2.7e-108 361.6 0.2 4.5e-108 360.8 0.2 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 PVD26091.1 - 3.3e-14 52.8 0.0 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 PVD26091.1 - 0.00022 20.6 1.6 0.00053 19.3 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 PVD26091.1 - 0.026 15.4 12.4 2.1 9.4 0.6 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat RLL PF10036.9 PVD26092.1 - 1.2e-59 202.3 0.4 1.4e-59 202.0 0.4 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Ion_trans PF00520.31 PVD26093.1 - 2.1e-34 118.9 21.9 3e-34 118.3 21.9 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 PVD26093.1 - 2.1e-20 72.9 0.0 4.5e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 PVD26093.1 - 1.3e-13 50.8 0.0 2.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD26093.1 - 1.6e-08 34.4 10.2 6.1e-08 32.5 10.2 2.1 1 1 0 1 1 1 1 Ion channel PAS PF00989.25 PVD26093.1 - 2.6e-07 30.6 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 PVD26093.1 - 2.8e-06 27.5 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 PVD26093.1 - 0.00056 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PBC PF03792.13 PVD26093.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 PBC domain PAS_8 PF13188.7 PVD26093.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain Cupin_2 PF07883.11 PVD26093.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Hamartin PF04388.12 PVD26093.1 - 0.15 10.7 12.3 0.23 10.1 12.3 1.3 1 0 0 1 1 1 0 Hamartin protein EGF_3 PF12947.7 PVD26094.1 - 5.1e-64 212.2 178.2 1.1e-07 31.9 10.2 12.4 12 0 0 12 12 12 11 EGF domain Ldl_recept_b PF00058.17 PVD26094.1 - 1.7e-28 98.8 3.4 9.7e-10 38.8 0.0 5.4 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B G2F PF07474.12 PVD26094.1 - 5.2e-23 81.8 0.0 1.3e-22 80.5 0.0 1.6 2 0 0 2 2 2 1 G2F domain EGF PF00008.27 PVD26094.1 - 8.7e-21 73.9 160.4 7.7e-05 22.9 4.3 12.8 12 0 0 12 12 12 11 EGF-like domain EGF_MSP1_1 PF12946.7 PVD26094.1 - 1.7e-18 66.3 153.5 0.00011 22.2 5.1 12.1 12 0 0 12 12 12 9 MSP1 EGF domain 1 NIDO PF06119.14 PVD26094.1 - 1e-15 58.4 0.1 2.6e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 Nidogen-like hEGF PF12661.7 PVD26094.1 - 5.3e-13 49.1 123.8 0.00041 20.9 5.4 14.5 13 1 0 13 13 12 9 Human growth factor-like EGF cEGF PF12662.7 PVD26094.1 - 1.3e-12 47.4 120.8 2.7e-05 24.0 2.9 12.6 12 0 0 12 12 12 7 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD26094.1 - 5.8e-09 36.0 21.2 1.5e-08 34.7 8.8 13.0 7 3 5 12 12 9 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD26094.1 - 2.7e-06 27.6 7.3 2.7e-06 27.6 7.3 12.1 10 2 2 12 12 11 3 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 PVD26094.1 - 0.00022 21.5 99.8 0.049 13.9 3.9 10.6 9 1 1 10 10 10 5 Pvs28 EGF domain SGL PF08450.12 PVD26094.1 - 0.0093 15.6 0.5 0.16 11.6 0.5 3.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PVD26094.1 - 0.075 13.2 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 1 0 Arylesterase DUF745 PF05335.13 PVD26095.1 - 0.022 14.5 0.3 0.022 14.5 0.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF745) COG2 PF06148.11 PVD26095.1 - 0.59 10.2 9.0 5.5 7.1 2.7 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 PVD26095.1 - 1.4 9.0 6.2 3 7.9 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 PVD26095.1 - 1.6 7.9 8.6 1.2 8.3 0.2 2.8 1 1 0 2 2 2 0 Monopolar spindle protein 2 UPF0242 PF06785.11 PVD26095.1 - 1.9 8.6 16.6 4.5 7.3 10.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 PVD26095.1 - 5.7 5.7 17.0 3 6.6 8.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 PVD26095.1 - 8 5.9 15.2 10 5.6 9.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 PVD26095.1 - 8.8 6.6 11.6 6.8 7.0 1.0 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil TAF6_C PF07571.13 PVD26096.1 - 1.8e-14 53.8 0.0 4.2e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PVD26096.1 - 0.0005 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CCSAP PF15748.5 PVD26097.1 - 5.5e-22 79.2 11.2 6.6e-22 78.9 11.2 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Ras PF00071.22 PVD26098.1 - 3.7e-29 101.4 0.0 4.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD26098.1 - 1.8e-08 34.6 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD26098.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family 2OG-FeII_Oxy_3 PF13640.6 PVD26099.1 - 1.6e-21 77.0 0.0 3.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 PVD26099.1 - 2e-10 40.5 12.5 3.6e-10 39.7 12.5 1.4 1 0 0 1 1 1 1 MYND finger 2OG-FeII_Oxy_4 PF13661.6 PVD26099.1 - 3.9e-10 40.3 0.0 7.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EGF PF00008.27 PVD26100.1 - 2.9e-24 85.0 74.4 4.4e-06 26.9 10.9 5.7 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 PVD26100.1 - 1.4e-08 35.0 57.2 0.0029 18.2 3.4 6.1 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.13 PVD26100.1 - 4.5e-05 23.7 86.1 0.12 12.8 10.1 6.2 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 PVD26100.1 - 0.27 11.5 67.5 0.48 10.7 6.8 5.6 4 1 1 5 5 5 0 Calcium-binding EGF domain Actin PF00022.19 PVD26102.1 - 1.7e-44 152.1 0.0 3.2e-42 144.6 0.0 2.1 1 1 1 2 2 2 2 Actin EF-hand_7 PF13499.6 PVD26103.1 - 2.6e-16 59.8 0.1 8.1e-13 48.6 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD26103.1 - 7.6e-15 53.3 0.7 5.7e-08 31.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PVD26103.1 - 8.5e-14 51.2 0.5 2.6e-07 30.4 0.1 3.1 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD26103.1 - 2.5e-10 39.4 0.1 6.1e-08 32.0 0.1 3.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 PVD26103.1 - 1.1e-08 34.1 0.5 4.1e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PVD26103.1 - 1.3e-05 25.4 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 PVD26103.1 - 0.093 12.9 0.6 0.17 12.1 0.6 1.4 1 0 0 1 1 1 0 Dockerin type I domain DUF4575 PF15143.6 PVD26104.1 - 0.084 13.1 2.2 0.39 10.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4575) Dicty_REP PF05086.12 PVD26105.1 - 0.33 8.9 1.1 0.39 8.6 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YjbE PF11106.8 PVD26105.1 - 1.2 9.4 8.2 3 8.1 8.2 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE DUF2465 PF10239.9 PVD26106.1 - 3.7e-118 394.5 0.0 4.3e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) CotJB PF12652.7 PVD26106.1 - 0.11 12.8 0.1 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 CotJB protein CSN8_PSD8_EIF3K PF10075.9 PVD26107.1 - 1.9e-33 115.4 0.0 2.7e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PVD26107.1 - 2.1e-05 24.0 0.2 3.2e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family Pro_racemase PF05544.11 PVD26109.1 - 6.3e-95 317.9 0.0 7.1e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DAP_epimerase PF01678.19 PVD26109.1 - 0.014 15.5 0.7 0.1 12.8 0.0 2.3 2 1 0 2 2 2 0 Diaminopimelate epimerase Na_Ca_ex PF01699.24 PVD26110.1 - 1e-26 93.7 13.7 1.2e-26 93.5 13.7 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein ABC2_membrane PF01061.24 PVD26110.1 - 0.49 9.8 9.0 0.017 14.6 2.2 1.9 2 0 0 2 2 2 0 ABC-2 type transporter Pilin_PilX PF11530.8 PVD26111.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Minor type IV pilin, PilX TSR PF18487.1 PVD26111.1 - 0.095 12.9 1.7 0.18 12.1 1.7 1.4 1 0 0 1 1 1 0 Thrombospondin type 1 repeat Calx-beta PF03160.14 PVD26112.1 - 2.7e-56 187.9 7.8 3.1e-36 123.5 2.7 2.1 2 0 0 2 2 2 2 Calx-beta domain DUF4843 PF16132.5 PVD26112.1 - 0.0013 18.3 0.0 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4843) tRNA_bind PF01588.20 PVD26112.1 - 0.093 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative tRNA binding domain DUF2149 PF09919.9 PVD26112.1 - 0.13 12.6 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF3343 PF11823.8 PVD26114.1 - 0.014 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Comm PF15957.5 PVD26114.1 - 0.12 12.7 2.2 12 6.2 0.2 2.5 2 0 0 2 2 2 0 Commissureless DHHC PF01529.20 PVD26114.1 - 0.43 10.7 7.0 0.65 10.1 0.2 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase CCCAP PF15964.5 PVD26115.1 - 3.8e-62 210.6 92.4 5.8e-61 206.7 92.4 2.5 1 1 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Ion_trans PF00520.31 PVD26115.1 - 2.7e-37 128.3 55.7 1.6e-25 89.8 27.4 3.1 2 1 1 3 3 3 2 Ion transport protein EF-hand_7 PF13499.6 PVD26115.1 - 0.091 13.2 0.0 0.47 10.9 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain pair DUF4853 PF16145.5 PVD26115.1 - 1.1 9.4 5.2 2.8 8.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4853) MoCF_biosynth PF00994.24 PVD26116.1 - 2.9e-31 108.1 0.0 4.7e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 PVD26116.1 - 1.2e-30 106.3 0.2 2.3e-30 105.4 0.2 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) CAF20 PF17052.5 PVD26116.1 - 0.31 11.2 1.2 0.71 10.0 1.2 1.6 1 0 0 1 1 1 0 Cap associated factor MoCF_biosynth PF00994.24 PVD26117.1 - 2.6e-17 62.8 0.1 2.9e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain AP_endonuc_2 PF01261.24 PVD26117.1 - 0.03 13.8 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel MoeA_C PF03454.15 PVD26118.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF3515 PF12028.8 PVD26119.1 - 0.081 12.7 0.2 0.089 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) DUF1635 PF07795.11 PVD26124.1 - 0.025 14.5 0.2 0.056 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) WH1 PF00568.23 PVD26125.1 - 3e-13 49.7 0.0 5.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 WH1 domain ABC2_membrane PF01061.24 PVD26126.1 - 1.6e-32 112.6 19.3 2.4e-32 112.1 19.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD26126.1 - 7e-21 75.2 0.1 3.6e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 PVD26126.1 - 0.00098 18.8 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD26126.1 - 0.02 14.8 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PVD26126.1 - 0.081 13.3 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 PVD26126.1 - 0.084 12.2 0.1 0.82 9.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.7 PVD26126.1 - 0.24 10.5 17.6 0.43 9.6 17.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 PVD26126.1 - 0.28 11.7 0.0 0.48 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD26127.1 - 2.8e-25 89.4 0.0 5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PVD26127.1 - 1.5e-18 67.0 17.0 1.5e-18 67.0 17.0 1.5 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 PVD26127.1 - 4.1e-06 26.8 1.4 0.015 15.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 PVD26127.1 - 0.00032 20.5 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 CDR ABC transporter SMC_N PF02463.19 PVD26127.1 - 0.00081 18.9 0.1 0.54 9.7 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PVD26127.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD26127.1 - 0.022 15.2 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 PVD26127.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PVD26127.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 PVD26127.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 PVD26127.1 - 0.14 11.7 0.1 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD26128.1 - 1.6e-21 77.3 0.0 7e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 PVD26128.1 - 1.2e-14 54.3 15.9 4.1e-14 52.5 15.9 1.9 1 1 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 PVD26128.1 - 2.2e-08 34.3 0.3 0.0071 16.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD26128.1 - 1.1e-05 25.0 0.3 0.036 13.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PVD26128.1 - 0.00076 19.2 0.1 0.0024 17.6 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD26128.1 - 0.0012 19.2 0.1 0.0042 17.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PVD26128.1 - 0.0014 18.3 0.5 0.0062 16.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PVD26128.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PVD26128.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 PVD26128.1 - 0.014 15.1 0.1 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PDR_CDR PF06422.12 PVD26128.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 CDR ABC transporter NACHT PF05729.12 PVD26128.1 - 0.078 12.9 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Globin PF00042.22 PVD26129.1 - 6.5e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Globin ABC1 PF03109.16 PVD26130.1 - 1.4e-34 118.8 0.1 3.1e-34 117.7 0.1 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PVD26130.1 - 5.4e-05 22.7 0.2 0.00077 18.9 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 PVD26130.1 - 0.035 14.0 0.0 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family SKIP_SNW PF02731.15 PVD26131.1 - 3.3e-73 244.6 4.0 3.3e-73 244.6 4.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Branch PF02485.21 PVD26132.1 - 4.5e-33 114.8 0.0 6.7e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD26133.1 - 9.5e-35 120.3 0.0 1.3e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD26134.1 - 6.6e-38 130.6 0.0 8.9e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Fibrillarin PF01269.17 PVD26135.1 - 8.6e-77 257.3 0.3 2.1e-40 138.2 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin DEAD PF00270.29 PVD26136.1 - 2.1e-41 141.6 0.0 3.3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD26136.1 - 1.7e-28 99.2 0.7 1e-27 96.6 0.6 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PVD26136.1 - 0.0078 15.5 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CHASE3 PF05227.13 PVD26137.1 - 0.0011 18.9 1.8 0.017 15.0 1.3 2.1 2 0 0 2 2 2 1 CHASE3 domain FAM184 PF15665.5 PVD26137.1 - 0.002 17.9 9.5 0.002 17.9 9.5 1.9 1 1 1 2 2 2 1 Family with sequence similarity 184, A and B Prominin PF05478.11 PVD26137.1 - 0.022 12.7 6.2 0.027 12.4 6.2 1.0 1 0 0 1 1 1 0 Prominin bZIP_2 PF07716.15 PVD26137.1 - 0.026 14.6 16.0 0.44 10.7 1.3 3.8 3 1 1 4 4 4 0 Basic region leucine zipper DUF4254 PF14063.6 PVD26137.1 - 0.076 12.8 6.0 1.8 8.3 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4254) DivIC PF04977.15 PVD26137.1 - 0.21 11.4 15.8 0.45 10.3 0.6 3.7 3 1 0 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.9 PVD26137.1 - 0.23 11.4 18.7 0.14 12.1 6.9 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain Rit1_C PF17184.4 PVD26137.1 - 0.24 10.8 5.6 0.11 11.9 2.6 1.7 1 1 1 2 2 2 0 Rit1 N-terminal domain ABC_tran_CTD PF16326.5 PVD26137.1 - 0.28 11.4 16.7 22 5.4 0.1 3.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain MCC-bdg_PDZ PF10506.9 PVD26137.1 - 0.3 11.1 6.3 3.2 7.8 0.0 3.0 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome OmpH PF03938.14 PVD26137.1 - 0.58 10.5 14.8 0.17 12.2 7.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 PVD26137.1 - 0.63 10.2 19.4 0.99 9.6 0.9 4.2 2 1 2 4 4 4 0 bZIP transcription factor GIT_CC PF16559.5 PVD26137.1 - 0.74 9.7 11.8 2.5 8.0 0.3 3.5 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vps51 PF08700.11 PVD26137.1 - 1.3 9.2 7.2 2.5 8.2 4.0 2.3 1 1 1 2 2 2 0 Vps51/Vps67 Exonuc_VII_L PF02601.15 PVD26137.1 - 1.4 8.4 7.7 1.7 8.1 7.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_Mu_Gam PF07352.12 PVD26137.1 - 3.1 7.7 14.2 0.14 12.1 4.7 2.2 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein KxDL PF10241.9 PVD26137.1 - 4.1 7.8 10.7 2.9 8.2 2.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Rootletin PF15035.6 PVD26137.1 - 4.9 7.1 20.7 0.74 9.8 15.0 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 PVD26137.1 - 6.3 7.1 11.3 0.82 9.9 0.3 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper CENP-H PF05837.12 PVD26137.1 - 6.9 7.1 15.3 3.2 8.2 6.1 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Glyco_hydro_35 PF01301.19 PVD26138.1 - 6.8e-97 324.9 0.9 8.9e-97 324.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 PVD26138.1 - 7.9e-16 58.3 0.3 2.8e-15 56.5 0.1 2.0 2 1 0 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 PVD26138.1 - 0.00027 20.5 0.0 0.00062 19.3 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SRCR PF00530.18 PVD26141.1 - 1.4e-21 76.8 0.3 1.4e-21 76.8 0.3 2.6 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain EGF_CA PF07645.15 PVD26141.1 - 1.2e-05 25.4 7.2 1.2e-05 25.4 7.2 4.7 4 0 0 4 4 4 2 Calcium-binding EGF domain SRCR_2 PF15494.6 PVD26141.1 - 0.00026 21.4 0.2 0.0011 19.5 0.2 2.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain EGF PF00008.27 PVD26141.1 - 0.008 16.5 5.8 0.008 16.5 5.8 4.7 4 0 0 4 4 4 1 EGF-like domain SRCR PF00530.18 PVD26142.1 - 1.6e-19 70.3 0.1 1.6e-19 70.3 0.1 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain EGF_CA PF07645.15 PVD26142.1 - 2.8e-05 24.2 7.5 2.8e-05 24.2 7.5 4.6 5 0 0 5 5 5 2 Calcium-binding EGF domain SRCR_2 PF15494.6 PVD26142.1 - 0.0038 17.7 0.1 0.018 15.6 0.1 2.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain I-set PF07679.16 PVD26143.1 - 1.6e-99 326.2 0.0 3.5e-13 49.4 0.0 11.1 10 1 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26143.1 - 4.8e-99 325.1 9.9 6.5e-13 49.1 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain fn3 PF00041.21 PVD26143.1 - 6.1e-71 234.8 13.0 2.4e-14 53.4 0.5 6.7 6 0 0 6 6 6 6 Fibronectin type III domain ig PF00047.25 PVD26143.1 - 5.8e-64 212.3 6.4 2.2e-10 40.6 0.1 10.3 10 1 0 10 10 9 8 Immunoglobulin domain Ig_2 PF13895.6 PVD26143.1 - 3.8e-61 203.4 9.9 4.8e-08 33.2 0.0 9.9 9 1 0 9 9 9 9 Immunoglobulin domain V-set PF07686.17 PVD26143.1 - 7.9e-24 83.9 25.1 0.0018 18.4 0.0 12.5 8 7 1 10 10 10 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD26143.1 - 1.6e-20 72.9 1.4 0.054 13.6 0.0 8.5 8 0 0 8 8 8 5 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD26143.1 - 6.4e-16 57.6 0.1 0.17 11.5 0.0 7.0 7 0 0 7 7 7 4 Immunoglobulin domain C1-set PF07654.15 PVD26143.1 - 1.3e-10 41.5 0.7 0.037 14.4 0.0 5.8 6 0 0 6 6 5 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 PVD26143.1 - 2e-10 40.9 0.0 0.63 10.5 0.0 7.8 7 2 1 8 8 8 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 PVD26143.1 - 3.5e-10 39.8 0.1 0.11 12.5 0.0 7.3 8 0 0 8 8 7 1 C17orf99 Ig domain Ig_4 PF16680.5 PVD26143.1 - 2.9e-08 33.9 0.1 23 5.3 0.0 8.3 8 2 0 8 8 7 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD26143.1 - 3.5e-07 30.2 0.2 0.11 12.5 0.0 5.6 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD26143.1 - 2.3e-06 28.1 13.8 0.34 11.5 0.1 6.5 6 0 0 6 6 5 3 Purple acid Phosphatase, N-terminal domain C2-set PF05790.15 PVD26143.1 - 4.8e-05 23.4 0.2 2.4 8.4 0.0 4.5 3 1 1 4 4 4 1 Immunoglobulin C2-set domain Tissue_fac PF01108.17 PVD26143.1 - 5.6e-05 22.9 0.0 0.26 11.2 0.0 3.8 3 0 0 3 3 3 1 Tissue factor fn3_2 PF16893.5 PVD26143.1 - 0.0099 16.0 0.0 6.6 7.0 0.1 3.0 2 0 0 2 2 2 1 Fibronectin type III domain Receptor_2B4 PF11465.8 PVD26143.1 - 0.019 15.1 3.4 36 4.6 0.0 5.2 4 1 1 5 5 5 0 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 PVD26143.1 - 0.039 12.7 2.9 23 3.6 0.0 4.6 3 1 1 4 4 4 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.15 PVD26143.1 - 6.9 6.5 9.8 19 5.1 0.4 5.5 7 0 0 7 7 7 0 Adenovirus E3 region protein CR1 NDK PF00334.19 PVD26145.1 - 3.2e-25 88.7 0.0 3.3e-12 46.6 0.0 4.4 4 0 0 4 4 4 3 Nucleoside diphosphate kinase Tetraspanin PF00335.20 PVD26146.1 - 7.4e-26 91.3 6.2 1.2e-25 90.6 6.2 1.3 1 1 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 PVD26147.1 - 8.2e-19 68.2 14.2 1.6e-18 67.3 14.2 1.5 1 1 0 1 1 1 1 Tetraspanin family WBP-1 PF11669.8 PVD26147.1 - 0.068 13.8 3.1 0.065 13.9 1.7 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 SP_C-Propep PF08999.10 PVD26147.1 - 1.6 8.6 11.5 0.58 10.0 0.8 3.2 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide RSN1_7TM PF02714.15 PVD26148.1 - 1.5e-49 168.8 23.2 1.5e-49 168.8 23.2 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 PVD26148.1 - 1.4e-37 129.6 0.2 2e-37 129.1 0.2 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PVD26148.1 - 5.6e-13 48.9 0.3 5.6e-13 48.9 0.3 4.4 4 2 2 6 6 6 2 Late exocytosis, associated with Golgi transport YpmT PF17431.2 PVD26148.1 - 0.14 12.2 1.3 0.46 10.5 1.3 1.9 1 0 0 1 1 1 0 Uncharacterized YmpT-like DUF962 PF06127.11 PVD26148.1 - 1.2 9.2 10.2 0.33 11.1 0.7 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF962) PAXX PF15384.6 PVD26149.1 - 1e-25 90.6 0.3 1.2e-25 90.3 0.3 1.0 1 0 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 XLF PF09302.11 PVD26149.1 - 0.0035 17.5 0.3 0.01 16.0 0.4 1.7 1 1 1 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF5043 PF16446.5 PVD26149.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) WD40 PF00400.32 PVD26150.1 - 4.7e-56 185.5 74.0 6e-05 23.7 0.1 26.4 28 0 0 28 28 27 11 WD domain, G-beta repeat HELP PF03451.14 PVD26150.1 - 4.6e-52 173.8 1.1 1.8e-20 72.6 0.1 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 PVD26150.1 - 5.3e-38 129.2 6.2 1.3e-06 28.6 0.0 14.1 10 3 6 16 16 15 7 Anaphase-promoting complex subunit 4 WD40 domain PDZ PF00595.24 PVD26150.1 - 1.7e-16 60.3 0.5 4.6e-16 58.9 0.5 1.7 1 0 0 1 1 1 1 PDZ domain eIF2A PF08662.11 PVD26150.1 - 6.7e-11 42.4 1.6 0.12 12.2 0.0 8.0 7 2 2 9 9 9 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD26150.1 - 1.1e-08 34.5 0.4 3.4 6.5 0.0 7.1 7 2 0 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PVD26150.1 - 3.9e-07 28.9 0.1 1.4 7.3 0.0 5.7 6 1 1 7 7 7 3 Cytochrome D1 heme domain PDZ_6 PF17820.1 PVD26150.1 - 1.7e-05 24.6 0.0 5.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PSII_BNR PF14870.6 PVD26150.1 - 3.8e-05 23.1 0.1 1.5 8.0 0.0 3.8 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 PDZ_2 PF13180.6 PVD26150.1 - 8.4e-05 22.8 0.0 0.00026 21.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain WD40_like PF17005.5 PVD26150.1 - 9.1e-05 21.9 4.3 0.07 12.5 0.0 5.8 8 0 0 8 8 8 1 WD40-like domain PD40 PF07676.12 PVD26150.1 - 0.00047 20.0 0.1 37 4.4 0.1 6.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 PVD26150.1 - 0.00093 18.3 0.5 4.3 6.3 0.0 4.7 6 0 0 6 6 6 1 Coatomer WD associated region Nucleoporin_N PF08801.11 PVD26150.1 - 0.0049 15.7 0.0 4.3 6.0 0.0 3.9 4 0 0 4 4 4 1 Nup133 N terminal like YsaB PF13983.6 PVD26150.1 - 0.006 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 YsaB-like lipoprotein PI3K_C2 PF00792.24 PVD26150.1 - 0.013 15.4 0.9 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Nup160 PF11715.8 PVD26150.1 - 0.088 11.4 0.0 28 3.2 0.0 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 SAM_4 PF18017.1 PVD26151.1 - 2.5e-30 104.3 0.0 5e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 PVD26151.1 - 1.5e-06 28.1 13.3 1.5e-06 28.1 13.3 3.1 1 1 1 3 3 3 1 Family of unknown function (DUF5577) SAM_1 PF00536.30 PVD26151.1 - 0.00018 21.9 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD26151.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ins134_P3_kin PF05770.11 PVD26152.1 - 4.3e-27 94.9 0.0 7.1e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 PVD26152.1 - 7e-11 42.4 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain SIT PF15330.6 PVD26153.1 - 4.7 7.7 7.0 1.8 9.0 4.6 1.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TPR_2 PF07719.17 PVD26154.1 - 5.4e-21 73.0 11.5 0.0089 16.1 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD26154.1 - 1.6e-15 56.2 14.5 0.082 12.8 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26154.1 - 2.1e-15 55.6 14.2 0.034 14.4 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 PVD26154.1 - 1.3e-09 38.1 0.9 0.76 10.8 0.1 6.2 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD26154.1 - 1.6e-09 37.9 7.7 0.018 15.3 0.1 5.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26154.1 - 4.3e-09 36.8 7.8 0.046 14.2 0.4 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PVD26154.1 - 2.8e-08 33.3 6.5 1.4e-06 27.8 0.1 3.9 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 PVD26154.1 - 1.8e-07 31.7 5.3 0.035 14.7 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD26154.1 - 2.3e-06 27.6 0.6 8.8 7.0 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD26154.1 - 3.2e-05 24.1 12.4 0.00014 22.0 0.7 3.6 3 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PVD26154.1 - 0.00035 20.6 0.4 0.029 14.4 0.2 3.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 PVD26154.1 - 0.0015 17.8 1.6 0.003 16.8 1.4 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD26154.1 - 0.0027 17.2 8.8 0.043 13.2 0.2 2.7 2 1 1 3 3 3 2 Coatomer epsilon subunit TPR_9 PF13371.6 PVD26154.1 - 0.012 15.8 0.5 0.064 13.4 0.2 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD26154.1 - 0.026 14.8 0.6 0.53 10.7 0.3 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26154.1 - 1 9.5 7.6 20 5.5 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 PVD26154.1 - 1.1 9.7 10.5 1 9.8 0.6 3.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain KTSC PF13619.6 PVD26155.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 KTSC domain LRR_6 PF13516.6 PVD26156.1 - 6.2e-05 22.7 0.3 0.0011 18.8 0.0 2.8 3 0 0 3 3 3 1 Leucine Rich repeat DUF561 PF04481.12 PVD26156.1 - 0.025 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) LRR_6 PF13516.6 PVD26157.1 - 2e-14 52.3 5.0 0.0038 17.2 0.1 5.8 5 0 0 5 5 5 5 Leucine Rich repeat LRR_1 PF00560.33 PVD26157.1 - 3.3e-06 26.9 0.7 0.49 11.1 0.0 4.4 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 PVD26157.1 - 2.5e-05 23.9 2.8 0.00085 19.0 1.5 3.3 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 PVD26157.1 - 0.2 12.1 0.2 0.2 12.1 0.2 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD26158.1 - 4.3e-25 85.6 21.4 0.001 18.9 0.0 9.2 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 PVD26158.1 - 3.6e-07 29.8 10.7 5.2 8.0 0.0 7.3 6 2 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.7 PVD26158.1 - 0.018 15.5 18.0 2.4 8.7 0.1 5.9 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD26158.1 - 0.47 10.2 19.4 0.4 10.5 2.1 6.2 5 1 1 6 6 6 0 Leucine rich repeat PAS_11 PF14598.6 PVD26159.1 - 6.8e-20 71.3 0.0 1.2e-14 54.4 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 PVD26159.1 - 4.9e-19 68.4 0.0 1.9e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 PVD26159.1 - 2.9e-12 46.6 0.0 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PVD26159.1 - 3e-05 24.2 0.0 0.062 13.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 PVD26159.1 - 0.00017 21.8 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 PVD26159.1 - 0.0017 18.3 0.6 0.0037 17.2 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 PVD26160.1 - 1.9e-38 132.4 0.0 3.2e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26160.1 - 3.1e-26 92.2 0.0 5.5e-26 91.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD26160.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like CH PF00307.31 PVD26161.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain SAM_1 PF00536.30 PVD26162.1 - 5.6e-09 36.3 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD26162.1 - 1.7e-08 34.5 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) VPS9 PF02204.18 PVD26166.1 - 4.1e-22 78.4 0.0 9.9e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 PVD26166.1 - 1e-09 38.9 0.0 3.9e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 PVD26166.1 - 3.2e-08 33.6 0.0 8.3e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 SH2 domain FERM_f0 PF16511.5 PVD26166.1 - 0.0094 16.2 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Spectrin PF00435.21 PVD26167.1 - 0 1091.3 967.9 8.2e-13 48.8 2.7 92.2 87 5 6 94 94 94 77 Spectrin repeat CH PF00307.31 PVD26167.1 - 2.7e-44 149.8 0.1 1.7e-21 76.4 0.0 5.5 3 0 0 3 3 3 2 Calponin homology (CH) domain KASH PF10541.9 PVD26167.1 - 1.2e-19 70.3 5.4 2.6e-19 69.2 5.4 1.6 1 0 0 1 1 1 1 Nuclear envelope localisation domain CAMSAP_CH PF11971.8 PVD26167.1 - 6.7e-06 25.8 0.0 0.0077 16.0 0.0 3.8 2 0 0 2 2 2 2 CAMSAP CH domain KKLCAg1 PF15204.6 PVD26167.1 - 1.3 9.2 4.3 1.8 8.7 0.5 3.2 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 MetOD1 PF18546.1 PVD26167.1 - 4.6 7.2 11.0 11 6.0 1.3 6.0 4 0 0 4 4 4 0 Metanogen output domain 1 TBCC PF07986.12 PVD26168.1 - 2.4e-44 149.9 1.2 4.6e-44 149.0 1.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 PVD26168.1 - 1.3e-28 99.8 4.5 2.4e-28 98.9 4.5 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF4760 PF15956.5 PVD26168.1 - 0.099 12.8 2.0 0.23 11.6 0.9 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4760) Tetraspanin PF00335.20 PVD26169.1 - 1.7e-13 50.9 4.0 1.2e-12 48.1 4.0 2.0 1 1 0 1 1 1 1 Tetraspanin family EOS1 PF12326.8 PVD26169.1 - 0.0066 16.4 0.1 0.022 14.7 0.1 1.8 1 1 0 1 1 1 1 N-glycosylation protein zf-C4 PF00105.18 PVD26170.1 - 2.4e-41 140.0 35.6 2.2e-25 88.9 17.7 2.8 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) HECT PF00632.25 PVD26171.1 - 3.9e-72 243.3 0.0 1.2e-71 241.7 0.0 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 PVD26171.1 - 1.5e-22 79.6 4.1 3.6e-22 78.4 4.1 1.7 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.13 PVD26171.1 - 4.2e-18 65.6 0.0 1.6e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Ank_2 PF12796.7 PVD26171.1 - 1.5e-13 51.1 0.0 1.2e-09 38.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD26171.1 - 2e-10 40.7 0.0 4.6e-06 26.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD26171.1 - 9.3e-08 32.5 0.0 1.9e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26171.1 - 3.2e-07 30.1 0.0 0.077 13.6 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PVD26171.1 - 6.8e-07 29.5 0.0 0.00039 20.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat F5_F8_type_C PF00754.25 PVD26171.1 - 5.4e-05 23.3 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain Lipase_chap PF03280.14 PVD26171.1 - 0.0021 18.1 4.4 0.0055 16.7 4.4 1.7 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein DUF116 PF01976.17 PVD26172.1 - 2 7.9 7.3 1.1 8.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF116 MFS_1 PF07690.16 PVD26173.1 - 1.3e-13 50.6 43.5 1.5e-11 43.9 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 PVD26173.1 - 0.00026 19.6 9.0 0.0047 15.4 1.4 2.3 2 1 0 2 2 2 2 Transmembrane secretion effector ARL2_Bind_BART PF11527.8 PVD26174.1 - 9.8e-28 96.6 3.2 9.8e-28 96.6 3.2 2.1 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Tau95_N PF17682.1 PVD26174.1 - 0.49 10.6 4.6 0.12 12.6 0.8 2.1 2 0 0 2 2 2 0 Tau95 Triple barrel domain SNAPc19 PF15497.6 PVD26174.1 - 7.3 7.1 21.4 4.9 7.7 4.7 3.0 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Sas10_Utp3 PF04000.15 PVD26175.1 - 1.6e-19 70.3 0.1 1.6e-19 70.3 0.1 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF932 PF06067.11 PVD26175.1 - 0.0024 17.7 0.3 0.0035 17.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF932) HMMR_C PF15908.5 PVD26175.1 - 0.015 15.5 1.3 0.02 15.2 0.6 1.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Cpn60_TCP1 PF00118.24 PVD26176.1 - 3.1e-26 92.1 0.0 5e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_38N PF01074.22 PVD26177.1 - 1.5e-62 211.6 8.6 3.6e-46 157.8 0.6 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PVD26177.1 - 2.6e-22 79.9 0.0 4.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PVD26177.1 - 2.8e-17 62.6 0.7 1e-16 60.8 0.7 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain 7TM_GPCR_Srx PF10328.9 PVD26178.1 - 0.00057 19.6 6.3 0.00057 19.6 6.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD26178.1 - 0.0095 15.9 0.7 0.017 15.1 0.7 1.4 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 PVD26178.1 - 0.056 12.8 8.3 0.09 12.1 8.1 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD26179.1 - 8.1e-05 22.1 5.3 0.00011 21.6 5.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD26179.1 - 0.00021 21.0 7.6 0.00029 20.5 7.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD26179.1 - 0.096 12.3 8.4 0.47 10.1 8.4 1.9 1 1 0 1 1 1 0 Srg family chemoreceptor 7tm_1 PF00001.21 PVD26180.1 - 7e-06 25.6 4.3 8.5e-06 25.3 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 PVD26180.1 - 7.8e-05 22.7 1.3 0.00011 22.3 1.3 1.2 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 PVD26180.1 - 0.00028 20.6 8.1 0.00039 20.1 8.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD26180.1 - 0.041 13.5 7.9 0.23 11.1 7.9 1.9 1 1 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD26181.1 - 4.5e-05 23.2 6.7 7.4e-05 22.5 6.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD26181.1 - 0.0001 21.8 3.8 0.00015 21.2 3.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 PVD26181.1 - 0.0034 17.4 0.9 0.0061 16.5 0.9 1.5 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa DUF1758 PF05585.12 PVD26181.1 - 0.051 13.3 0.5 0.093 12.5 0.5 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) YibE_F PF07907.11 PVD26181.1 - 0.47 9.9 12.5 0.04 13.4 6.9 1.9 1 1 1 2 2 2 0 YibE/F-like protein 7tm_1 PF00001.21 PVD26182.1 - 0.00028 20.3 3.8 0.00046 19.6 3.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD26182.1 - 0.00073 19.2 7.0 0.0015 18.2 7.0 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx YibE_F PF07907.11 PVD26182.1 - 0.0073 15.8 5.4 0.0073 15.8 5.4 2.0 1 1 1 2 2 2 1 YibE/F-like protein Metallophos PF00149.28 PVD26183.1 - 1.3e-18 68.3 0.2 2.2e-18 67.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PVD26183.1 - 4.5e-15 56.3 0.4 1.3e-14 54.8 0.4 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PVD26183.1 - 3.2e-07 30.8 4.9 2.3e-05 24.9 0.3 2.8 2 1 1 3 3 3 2 Purple acid Phosphatase, N-terminal domain Acylphosphatase PF00708.18 PVD26184.1 - 2.6e-24 85.4 1.6 2.9e-24 85.3 1.6 1.0 1 0 0 1 1 1 1 Acylphosphatase Y_phosphatase PF00102.27 PVD26185.1 - 2.5e-72 243.3 1.6 3.3e-72 242.9 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FERM_M PF00373.18 PVD26185.1 - 5.2e-22 78.5 0.6 1.8e-21 76.7 0.1 2.3 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 PVD26185.1 - 1.4e-18 66.6 0.1 4e-18 65.1 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 PVD26185.1 - 3.1e-10 40.3 0.0 7.1e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.20 PVD26185.1 - 2.1e-05 24.3 0.0 6.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD26185.1 - 0.0036 17.3 2.5 0.0087 16.1 0.0 2.5 3 0 0 3 3 3 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD26185.1 - 0.019 15.1 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate CENP-F_N PF10481.9 PVD26186.1 - 7.1e-60 203.2 68.1 1.9e-31 109.9 22.8 8.2 4 2 3 8 8 8 2 Cenp-F N-terminal domain SHE3 PF17078.5 PVD26186.1 - 0.0081 15.9 17.3 0.0081 15.9 17.3 9.2 2 2 5 8 8 8 2 SWI5-dependent HO expression protein 3 DUF2774 PF11242.8 PVD26186.1 - 0.084 13.1 0.8 19 5.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) WD40_alt PF14077.6 PVD26186.1 - 0.85 9.5 17.9 0.53 10.2 0.3 6.7 4 1 1 5 5 5 0 Alternative WD40 repeat motif ATG16 PF08614.11 PVD26186.1 - 6.1 7.0 243.1 0.71 10.1 22.5 10.5 1 1 9 10 10 10 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 PVD26187.1 - 0.00042 20.5 20.6 0.00042 20.5 20.6 6.2 1 1 5 6 6 6 3 Tropomyosin like Fez1 PF06818.15 PVD26187.1 - 0.0079 16.7 98.9 0.48 10.9 22.0 5.1 1 1 2 4 4 4 2 Fez1 CENP-F_leu_zip PF10473.9 PVD26187.1 - 0.038 14.0 122.0 0.023 14.7 21.7 6.2 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 PVD26187.1 - 1.5 8.9 111.7 0.11 12.5 11.3 6.8 1 1 6 7 7 7 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 PVD26187.1 - 4.6 7.3 112.0 0.077 13.1 8.4 7.5 2 1 3 7 7 7 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 PVD26187.1 - 4.8 6.0 110.3 1.3 7.8 9.9 5.8 1 1 5 6 6 6 0 Spc7 kinetochore protein HrpF PF06266.12 PVD26187.1 - 6.1 7.2 7.8 14 6.1 0.4 3.7 4 0 0 4 4 4 0 HrpF protein Filament PF00038.21 PVD26187.1 - 6.4 6.3 98.7 0.069 12.7 10.1 6.8 1 1 4 6 6 6 0 Intermediate filament protein DUF1664 PF07889.12 PVD26187.1 - 9.5 6.3 64.9 0.13 12.3 7.6 7.7 1 1 6 7 7 7 0 Protein of unknown function (DUF1664) FPP PF05911.11 PVD26188.1 - 0.00015 20.1 34.3 0.00015 20.1 34.3 6.5 1 1 5 6 6 5 2 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 PVD26188.1 - 0.00022 21.3 221.0 0.025 14.6 17.6 10.2 2 2 8 10 10 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 PVD26188.1 - 0.00025 19.8 30.7 0.00025 19.8 30.7 6.1 1 1 5 6 6 6 2 AAA domain DUF1664 PF07889.12 PVD26188.1 - 0.0009 19.3 6.4 0.0009 19.3 6.4 12.0 2 2 10 13 13 12 4 Protein of unknown function (DUF1664) HMMR_N PF15905.5 PVD26188.1 - 0.007 15.9 26.4 0.007 15.9 26.4 7.7 1 1 7 8 8 6 3 Hyaluronan mediated motility receptor N-terminal zf-C4H2 PF10146.9 PVD26188.1 - 0.011 16.1 14.8 0.011 16.1 14.8 8.4 1 1 6 8 8 6 0 Zinc finger-containing protein Tropomyosin_1 PF12718.7 PVD26188.1 - 0.014 15.6 18.7 0.014 15.6 18.7 10.5 2 2 7 9 9 9 0 Tropomyosin like CALCOCO1 PF07888.11 PVD26188.1 - 0.016 14.1 185.8 0.025 13.5 36.0 5.4 1 1 3 5 5 5 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 PVD26188.1 - 0.11 12.3 195.4 0.026 14.4 22.1 6.9 1 1 6 7 7 7 0 Ezrin/radixin/moesin family Spc7 PF08317.11 PVD26188.1 - 0.17 10.7 201.5 0.025 13.5 23.0 9.0 1 1 8 10 10 9 0 Spc7 kinetochore protein Fez1 PF06818.15 PVD26188.1 - 0.82 10.1 178.6 0.049 14.1 16.3 7.9 1 1 7 8 8 8 0 Fez1 BRX_N PF13713.6 PVD26188.1 - 1.4 8.7 7.8 1.6 8.6 0.1 4.0 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain Golgin_A5 PF09787.9 PVD26188.1 - 2.1 7.8 199.4 0.047 13.1 22.4 7.1 1 1 6 7 7 7 0 Golgin subfamily A member 5 ATG16 PF08614.11 PVD26188.1 - 2.6 8.2 203.0 0.26 11.5 22.2 10.4 1 1 9 10 10 9 0 Autophagy protein 16 (ATG16) WD40_alt PF14077.6 PVD26188.1 - 4.4 7.2 11.4 2.3 8.2 0.3 5.3 4 0 0 4 4 3 0 Alternative WD40 repeat motif MAD PF05557.13 PVD26188.1 - 5.2 5.3 193.6 0.015 13.7 15.5 6.3 1 1 5 6 6 6 0 Mitotic checkpoint protein CbiX PF01903.17 PVD26188.1 - 5.5 7.4 8.4 52 4.2 0.2 4.9 4 0 0 4 4 3 0 CbiX Myosin_tail_1 PF01576.19 PVD26188.1 - 5.6 4.6 196.8 0.1 10.4 74.7 3.6 1 1 2 3 3 3 0 Myosin tail GAS PF13851.6 PVD26188.1 - 5.7 6.2 208.9 0.87 8.9 19.2 9.9 1 1 8 9 9 9 0 Growth-arrest specific micro-tubule binding 2OG-FeII_Oxy_2 PF13532.6 PVD26190.1 - 1e-09 38.9 0.0 1.7e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribonuclease_3 PF00636.26 PVD26191.1 - 2.9e-59 198.2 0.1 2.2e-33 115.0 0.0 4.0 4 0 0 4 4 4 2 Ribonuclease III domain PAZ PF02170.22 PVD26191.1 - 4.4e-36 123.7 0.2 1e-35 122.5 0.2 1.6 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 PVD26191.1 - 5.7e-25 87.3 0.1 2e-24 85.6 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 PVD26191.1 - 7.6e-23 81.1 0.1 3.5e-15 56.3 0.1 4.5 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 PVD26191.1 - 2e-14 53.9 0.0 5.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 PVD26191.1 - 0.00017 22.2 0.0 0.0019 18.9 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif DEAD PF00270.29 PVD26191.1 - 0.15 11.8 0.1 2 8.2 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase ETRAMP PF09716.10 PVD26192.1 - 0.059 13.4 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ferlin_C PF16165.5 PVD26193.1 - 0.95 9.4 4.9 1.2 9.1 4.9 1.2 1 0 0 1 1 1 0 Ferlin C-terminus RR_TM4-6 PF06459.12 PVD26193.1 - 1.2 8.9 7.5 1.3 8.8 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 PVD26193.1 - 3.1 6.0 8.3 3.2 5.9 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 PVD26193.1 - 3.7 7.2 4.8 4 7.1 4.8 1.1 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 PVD26193.1 - 4.1 6.1 6.0 4 6.1 6.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PVD26193.1 - 9.1 4.9 7.0 9.8 4.8 7.0 1.0 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.21 PVD26194.1 - 1.4e-108 363.3 0.0 9.8e-55 186.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PVD26194.1 - 2.6e-06 26.9 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 2 Beta-eliminating lyase Aminotran_5 PF00266.19 PVD26194.1 - 3.2e-06 26.3 0.0 0.032 13.2 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PVD26194.1 - 0.0013 18.1 0.0 3.1 7.0 0.0 3.2 2 2 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family AAA_lid_9 PF17871.1 PVD26194.1 - 0.0076 16.2 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 2 AAA lid domain CSN5_C PF18323.1 PVD26194.1 - 0.053 14.4 0.0 14 6.6 0.0 2.5 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Spec3 PF15795.5 PVD26195.1 - 3.7e-26 91.5 6.9 5.4e-26 90.9 6.9 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein Spec3 PF15795.5 PVD26196.1 - 4.3e-24 84.9 14.5 5.6e-24 84.5 14.5 1.1 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein RRM_1 PF00076.22 PVD26197.1 - 7.7e-12 44.9 0.5 1.1e-11 44.4 0.5 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PVD26197.1 - 2.5e-08 33.6 3.1 4.7e-08 32.8 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD26197.1 - 0.00013 21.7 1.8 0.00027 20.7 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 PVD26197.1 - 0.016 15.2 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 PVD26197.1 - 0.6 9.9 6.4 0.2 11.4 3.3 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RRM_1 PF00076.22 PVD26198.1 - 2.6e-18 65.6 0.6 3.7e-18 65.1 0.6 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PVD26198.1 - 2.5e-07 30.5 4.1 5e-07 29.5 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Limkain-b1 PF11608.8 PVD26198.1 - 0.00069 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Limkain b1 zf-CCHC_2 PF13696.6 PVD26198.1 - 0.001 18.8 3.4 0.0018 18.0 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Calcipressin PF04847.12 PVD26198.1 - 0.0024 17.6 0.1 0.0034 17.2 0.1 1.1 1 0 0 1 1 1 1 Calcipressin zf-CCHC_3 PF13917.6 PVD26198.1 - 0.0057 16.6 0.6 0.012 15.5 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 PVD26198.1 - 0.0086 16.2 0.0 0.039 14.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC_5 PF14787.6 PVD26198.1 - 0.02 14.6 3.6 0.038 13.7 3.6 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RRM_occluded PF16842.5 PVD26198.1 - 0.04 13.8 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PVD26198.1 - 0.051 13.6 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif eIF3g PF12353.8 PVD26198.1 - 0.15 12.5 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RRM_3 PF08777.11 PVD26198.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Ribosomal_S10 PF00338.22 PVD26199.1 - 2.7e-23 82.0 0.2 4.5e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e LRR_4 PF12799.7 PVD26200.1 - 5.8e-11 42.5 3.1 1e-05 25.8 0.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD26200.1 - 2.2e-07 30.6 0.0 5.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD26200.1 - 0.00018 21.2 2.1 0.00066 19.4 1.3 2.2 2 1 0 2 2 2 1 Leucine rich repeat Zein-binding PF04576.15 PVD26201.1 - 0.012 15.9 1.9 0.012 15.9 1.9 2.5 2 1 1 3 3 3 0 Zein-binding Fib_alpha PF08702.10 PVD26201.1 - 0.032 14.4 0.6 0.032 14.4 0.6 3.9 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.11 PVD26201.1 - 0.19 11.0 9.3 0.097 12.0 6.5 1.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Lectin_N PF03954.14 PVD26201.1 - 0.24 11.2 2.2 0.4 10.4 1.1 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 PVD26201.1 - 0.53 9.6 9.8 0.46 9.8 7.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 PVD26201.1 - 0.59 10.5 9.5 3.4 8.0 0.7 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family 5_nucleotid PF05761.14 PVD26201.1 - 0.68 8.8 5.6 1.4 7.8 5.6 1.5 1 0 0 1 1 1 0 5' nucleotidase family V_ATPase_I PF01496.19 PVD26201.1 - 0.79 7.6 6.6 1.2 6.9 6.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 PVD26201.1 - 1.4 9.4 10.0 0.9 10.0 1.3 3.5 3 1 1 4 4 4 0 Snapin/Pallidin DUF3450 PF11932.8 PVD26201.1 - 1.7 7.9 14.3 0.053 12.8 6.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) CP12 PF02672.15 PVD26201.1 - 2.4 9.0 5.4 2 9.2 1.5 2.7 2 1 1 3 3 3 0 CP12 domain CENP-H PF05837.12 PVD26201.1 - 2.8 8.4 17.7 5.8 7.4 11.0 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 PVD26201.1 - 2.9 8.2 22.9 1.9 8.7 9.7 4.4 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding HalX PF08663.10 PVD26201.1 - 3.1 8.2 16.7 0.19 12.1 4.0 4.1 4 0 0 4 4 4 0 HalX domain CorA PF01544.18 PVD26201.1 - 8.9 5.5 7.0 1.8 7.8 3.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein AMP-binding PF00501.28 PVD26202.1 - 6.6e-100 334.7 0.0 8.5e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD26202.1 - 1e-10 42.4 0.3 2.6e-10 41.1 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TTKRSYEDQ PF10212.9 PVD26203.1 - 1.1e-184 615.3 17.2 1.1e-184 615.3 17.2 2.2 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 PVD26203.1 - 1.1e-29 102.6 8.9 1.1e-29 102.6 8.9 5.6 6 1 0 6 6 6 1 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 PVD26203.1 - 0.0087 16.2 17.4 0.0087 16.2 17.4 5.8 4 2 1 5 5 5 2 Tropomyosin like Filament PF00038.21 PVD26203.1 - 0.4 10.2 57.3 0.064 12.8 0.9 4.2 4 1 0 4 4 4 0 Intermediate filament protein Aegerolysin PF06355.13 PVD26205.1 - 0.0061 16.6 2.6 12 6.0 0.0 3.2 3 0 0 3 3 3 3 Aegerolysin DUF5456 PF17539.2 PVD26205.1 - 0.015 15.1 0.3 29 4.5 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5456) DUF3836 PF12930.7 PVD26205.1 - 0.13 12.0 2.3 21 4.9 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF3836) amfpi-1 PF12190.8 PVD26205.1 - 0.75 10.4 9.4 6.7 7.4 0.3 3.7 3 0 0 3 3 3 0 Fungal protease inhibitor zf-C2H2 PF00096.26 PVD26206.1 - 2.4e-13 49.7 26.7 8.6e-05 22.8 4.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD26206.1 - 2.8e-10 40.1 25.7 0.001 19.7 3.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD26206.1 - 1.6e-09 37.8 30.0 1.5e-07 31.5 2.7 4.8 4 1 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 PVD26206.1 - 4.8e-07 29.9 12.4 0.021 15.2 0.7 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD26206.1 - 6.6e-07 29.2 14.5 0.015 15.2 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD26206.1 - 4.3e-05 23.7 12.1 0.051 13.9 0.9 3.7 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 PVD26206.1 - 0.031 13.9 9.7 4.6 6.9 0.1 4.2 3 1 1 4 4 4 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 PVD26206.1 - 0.46 10.8 12.0 3.8 7.9 3.8 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon DZR PF12773.7 PVD26206.1 - 1.8 8.7 7.3 8.1 6.6 1.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 PVD26206.1 - 2.1 8.5 11.1 8.4 6.6 0.9 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 PVD26206.1 - 3.2 7.8 11.1 21 5.2 0.4 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 PVD26206.1 - 3.2 8.1 15.3 4.4 7.7 1.8 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 PVD26206.1 - 3.6 7.5 11.0 0.6 10.0 3.0 2.6 1 1 1 2 2 2 0 GAGA factor Spectrin PF00435.21 PVD26207.1 - 1.1e-63 212.3 22.7 1.4e-20 73.7 5.5 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 PVD26207.1 - 1.5e-55 186.1 0.1 2.3e-28 98.5 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 PVD26207.1 - 2.9e-27 94.6 0.1 1.6e-26 92.2 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 PVD26207.1 - 1.9e-10 39.5 2.5 6.5e-05 22.2 0.1 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 PVD26207.1 - 5.8e-09 35.7 0.0 7.6e-08 32.1 0.1 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 PVD26207.1 - 2.8e-07 30.9 1.9 6.7e-07 29.7 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD26207.1 - 6.9e-07 28.7 0.3 0.012 15.4 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD26207.1 - 0.0004 20.2 0.0 0.0017 18.1 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair CtIP_N PF10482.9 PVD26207.1 - 0.014 15.5 2.5 0.014 15.5 2.5 3.4 3 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Terminase_4 PF05119.12 PVD26207.1 - 0.061 13.8 0.9 3.7 8.1 0.0 3.2 1 1 1 2 2 2 0 Phage terminase, small subunit VPS11_C PF12451.8 PVD26207.1 - 0.14 12.4 0.7 17 5.8 0.3 3.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal BLI1 PF17324.2 PVD26207.1 - 1.5 9.5 6.1 1.6 9.4 0.1 3.3 3 1 0 3 3 2 0 BLOC-1 interactor 1 PET117 PF15786.5 PVD26208.1 - 0.0013 18.9 2.3 0.002 18.3 2.3 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial EGF_MSP1_1 PF12946.7 PVD26209.1 - 2.9e-05 24.0 37.6 0.51 10.4 1.6 8.3 2 2 6 8 8 8 7 MSP1 EGF domain 1 fn3 PF00041.21 PVD26209.1 - 0.014 15.7 13.7 1.1 9.7 0.2 4.5 4 1 0 4 4 4 0 Fibronectin type III domain Lamprin PF06403.11 PVD26209.1 - 1 9.3 15.1 0.12 12.4 1.1 3.7 3 1 1 4 4 4 0 Lamprin TGF_beta PF00019.20 PVD26211.1 - 1.7e-37 128.6 1.2 3.5e-37 127.5 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD26211.1 - 4.8e-18 65.8 0.0 7.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide WD40 PF00400.32 PVD26213.1 - 3.9e-27 94.0 28.5 5.3e-07 30.2 0.2 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat F-box PF00646.33 PVD26213.1 - 4.1e-12 45.7 4.7 8.9e-12 44.6 4.7 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 PVD26213.1 - 2.2e-09 37.1 0.0 5.9e-06 25.8 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain F-box-like PF12937.7 PVD26213.1 - 2.3e-09 37.0 2.9 2.3e-09 37.0 2.9 2.0 2 0 0 2 2 2 1 F-box-like DUF4508 PF14969.6 PVD26213.1 - 6.2e-05 23.2 1.8 0.3 11.4 0.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) ANAPC4_WD40 PF12894.7 PVD26213.1 - 0.0024 18.2 0.0 0.47 10.8 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ISK_Channel PF02060.15 PVD26214.1 - 0.034 13.9 0.6 0.059 13.1 0.6 1.5 1 1 0 1 1 1 0 Slow voltage-gated potassium channel Pkinase PF00069.25 PVD26215.1 - 5.5e-70 235.7 0.0 9.5e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26215.1 - 3.9e-35 121.4 0.0 7.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 PVD26215.1 - 2.6e-26 91.2 22.7 4.9e-13 48.7 9.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 PVD26215.1 - 6.7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like C1_2 PF03107.16 PVD26215.1 - 2.6e-07 30.9 15.7 0.0011 19.2 3.0 2.5 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 PVD26215.1 - 9.9e-06 25.1 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 PVD26215.1 - 2e-05 25.0 0.1 5.6e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 PH domain zf-RING_9 PF13901.6 PVD26215.1 - 0.0029 17.6 15.6 0.019 14.9 1.6 2.5 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon APH PF01636.23 PVD26215.1 - 0.013 15.4 0.0 0.079 12.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 PVD26215.1 - 0.038 13.9 18.7 0.29 11.1 3.2 2.5 2 0 0 2 2 2 0 PHD-finger RIO1 PF01163.22 PVD26215.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family PHD_2 PF13831.6 PVD26215.1 - 0.37 10.4 9.9 0.57 9.8 0.6 2.8 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 PVD26215.1 - 0.57 10.4 12.5 0.62 10.3 3.9 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 PVD26215.1 - 2.3 8.2 16.3 2 8.4 2.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 E6 PF00518.17 PVD26215.1 - 5.9 7.4 11.5 10 6.6 1.2 2.5 2 0 0 2 2 2 0 Early Protein (E6) DUF382 PF04037.13 PVD26216.1 - 1.2e-58 196.8 1.4 1.2e-58 196.8 1.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 PVD26216.1 - 3.6e-19 68.4 3.1 1.7e-18 66.2 3.1 2.3 1 0 0 1 1 1 1 PSP Ribosomal_L11 PF00298.19 PVD26217.1 - 1.4e-25 89.5 0.1 3.1e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 PVD26217.1 - 3.3e-23 81.3 0.7 7.7e-23 80.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 PVD26218.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26218.1 - 3.1e-11 43.1 0.0 5.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 PVD26218.1 - 1.6e-10 40.3 0.1 0.032 14.5 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 PVD26218.1 - 1.8e-05 23.5 0.1 4.1e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PVD26218.1 - 2e-05 24.7 0.1 0.018 15.1 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PVD26218.1 - 5.9e-05 23.5 0.0 0.35 11.4 0.1 4.5 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 PVD26218.1 - 0.00079 19.8 0.0 0.045 14.2 0.0 2.8 1 1 1 2 2 2 1 HEAT repeats Kinase-like PF14531.6 PVD26218.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CLASP_N PF12348.8 PVD26218.1 - 0.017 14.7 0.2 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal U1snRNP70_N PF12220.8 PVD26218.1 - 1.7 9.3 5.3 3.8 8.2 2.4 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Inositol_P PF00459.25 PVD26219.1 - 2.3e-34 119.2 0.0 3e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FAM165 PF14981.6 PVD26219.1 - 0.085 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 FAM165 family LMBR1 PF04791.16 PVD26220.1 - 0.004 16.1 0.2 0.0054 15.7 0.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Synaptobrevin PF00957.21 PVD26220.1 - 0.1 12.4 1.0 5.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Synaptobrevin Tmemb_9 PF05434.11 PVD26220.1 - 1.4 8.8 5.2 0.28 11.0 0.3 2.1 2 0 0 2 2 2 0 TMEM9 DUF4619 PF15398.6 PVD26221.1 - 1e-08 35.1 14.3 1.2e-08 34.9 14.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) MAP7 PF05672.11 PVD26221.1 - 0.66 9.7 42.5 1.5 8.5 42.5 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Borrelia_P83 PF05262.11 PVD26221.1 - 6.3 5.2 20.9 7 5.0 20.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PLAT PF01477.23 PVD26222.1 - 3.9e-52 175.8 9.0 1.3e-18 67.6 0.1 4.3 3 1 0 4 4 4 3 PLAT/LH2 domain ATS3 PF06232.11 PVD26222.1 - 7.5e-08 32.3 0.0 0.047 13.6 0.0 3.4 3 0 0 3 3 3 3 Embryo-specific protein 3, (ATS3) LegC3_N PF18654.1 PVD26222.1 - 1.3 8.2 7.8 4.8 6.3 6.3 2.1 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Pox_A_type_inc PF04508.12 PVD26223.1 - 1.9e-05 24.3 0.1 1.9e-05 24.3 0.1 8.5 10 0 0 10 10 10 1 Viral A-type inclusion protein repeat HIP1_clath_bdg PF16515.5 PVD26223.1 - 0.0023 18.5 14.4 0.0023 18.5 14.4 23.8 7 7 15 24 24 24 2 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 PVD26223.1 - 0.0044 17.3 23.9 0.0044 17.3 23.9 17.9 2 2 10 14 14 14 1 Autophagy protein 16 (ATG16) PKHD_C PF18331.1 PVD26223.1 - 0.32 11.1 2.0 2.5 8.2 0.1 3.9 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain Tautomerase PF01361.21 PVD26223.1 - 0.37 10.8 1.8 1.7 8.6 1.2 2.5 2 0 0 2 2 2 0 Tautomerase enzyme DUF4894 PF16235.5 PVD26223.1 - 0.46 10.9 6.3 0.16 12.3 0.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4894) Ald_Xan_dh_C2 PF02738.18 PVD26224.1 - 1.4e-161 538.7 0.0 8e-97 325.0 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PVD26224.1 - 1.4e-30 106.3 0.0 3.5e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 PVD26224.1 - 1e-29 103.1 0.1 2.1e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 PVD26224.1 - 1e-25 89.9 0.0 2.9e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Tristanin_u2 PF16638.5 PVD26225.1 - 8.1 7.3 16.6 6.1 7.7 3.7 3.0 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Ank_4 PF13637.6 PVD26227.1 - 3.3e-08 33.9 0.5 2.1e-05 24.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26227.1 - 6.3e-08 33.1 0.3 5.4e-06 26.9 0.3 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD26227.1 - 4.1e-07 30.1 1.7 0.029 14.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PVD26227.1 - 3e-06 27.1 0.1 0.11 13.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD26227.1 - 3.4e-05 24.0 0.8 0.011 16.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26230.1 - 6.1e-29 100.4 11.1 2.8e-11 43.8 0.5 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26230.1 - 9e-19 65.6 7.7 0.00026 21.2 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD26230.1 - 4.1e-17 62.0 13.0 5.5e-05 23.4 0.3 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD26230.1 - 1.3e-16 60.7 8.8 2.3e-05 24.8 0.2 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD26230.1 - 7.7e-14 51.4 16.6 6.4e-05 23.2 0.7 5.5 6 0 0 6 6 6 4 Ankyrin repeat Methyltransf_31 PF13847.6 PVD26231.1 - 2.5e-06 27.4 0.0 2.9e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD26231.1 - 3.8e-05 23.6 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD26231.1 - 5.2e-05 23.8 0.0 9.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD26231.1 - 0.00025 21.7 0.0 0.00041 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Phenol_MetA_deg PF13557.6 PVD26231.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation HIT PF01230.23 PVD26233.1 - 1.6 9.5 4.3 11 6.8 2.2 3.1 3 1 0 3 3 3 0 HIT domain Ald_Xan_dh_C2 PF02738.18 PVD26234.1 - 2.3e-164 547.9 0.1 3.6e-104 349.2 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase CO_deh_flav_C PF03450.17 PVD26234.1 - 2.4e-33 114.4 0.0 1.6e-32 111.7 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 PVD26234.1 - 1.4e-31 109.6 0.0 5.2e-31 107.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 PVD26234.1 - 2.4e-30 105.1 0.1 4.7e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD26234.1 - 7.6e-28 96.4 0.1 1.6e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain ADAM_CR_2 PF17771.1 PVD26235.1 - 3.2e-17 62.8 4.7 3.2e-17 62.8 4.7 2.5 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 PVD26235.1 - 3.1e-12 46.8 0.1 5.1e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD26235.1 - 8.8e-10 39.1 0.1 1.5e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 PVD26235.1 - 1e-08 35.4 0.4 1.9e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD26235.1 - 6.3e-07 29.2 0.2 1e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD26235.1 - 0.00025 21.5 0.1 0.00046 20.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD26235.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Cystatin PF00031.21 PVD26238.1 - 7.6e-09 35.7 0.3 0.0029 17.8 0.0 2.3 2 0 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 PVD26238.1 - 0.00021 21.6 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Cystatin PF00031.21 PVD26239.1 - 4.7e-05 23.6 0.4 6.2e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.21 PVD26240.1 - 1.4e-10 41.3 0.2 0.00023 21.3 0.1 2.5 2 0 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 PVD26240.1 - 0.0042 17.4 0.0 2.3 8.6 0.0 2.3 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor CHASE4 PF05228.13 PVD26240.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain Cystatin PF00031.21 PVD26241.1 - 4.8e-16 58.8 0.3 0.0021 18.3 0.0 4.6 4 1 0 4 4 4 4 Cystatin domain SQAPI PF16845.5 PVD26241.1 - 0.0019 18.5 0.1 21 5.6 0.0 4.1 4 0 0 4 4 4 2 Aspartic acid proteinase inhibitor Asparaginase PF00710.20 PVD26242.1 - 1.3e-46 158.5 0.0 2.9e-46 157.4 0.0 1.6 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PVD26242.1 - 9.4e-31 106.4 0.1 2.1e-30 105.3 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 PVD26242.1 - 1.8e-26 92.2 11.7 2.3e-09 37.6 0.3 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26242.1 - 5.6e-22 78.1 5.9 4.6e-13 49.6 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD26242.1 - 4.4e-20 71.5 3.4 4.5e-09 36.4 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26242.1 - 1.2e-14 53.0 2.3 6.8e-06 26.0 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PVD26242.1 - 7.5e-13 48.3 14.0 2.3e-06 27.8 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeat Tam41_Mmp37 PF09139.11 PVD26243.1 - 9.6e-108 360.4 1.5 1.5e-107 359.8 0.4 1.7 2 0 0 2 2 2 1 Phosphatidate cytidylyltransferase, mitochondrial Complex1_LYR PF05347.15 PVD26243.1 - 1.5e-10 40.9 0.4 4.1e-10 39.6 0.4 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PVD26243.1 - 0.0071 17.1 1.8 0.012 16.3 0.2 2.2 2 0 0 2 2 2 1 Complex1_LYR-like Asparaginase_2 PF01112.18 PVD26244.1 - 9.8e-47 159.5 0.9 2.1e-46 158.4 0.9 1.5 1 0 0 1 1 1 1 Asparaginase SH3_9 PF14604.6 PVD26244.1 - 1.6e-07 31.1 0.0 5e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.9 PVD26244.1 - 4.7e-07 29.8 0.2 0.00027 20.7 0.0 3.1 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase SH3_2 PF07653.17 PVD26244.1 - 0.00088 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD26244.1 - 0.01 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 SH3 domain zf-TRAF PF02176.18 PVD26245.1 - 1.7e-15 57.4 34.8 4.5e-11 43.3 6.6 4.0 1 1 3 4 4 4 3 TRAF-type zinc finger Sina PF03145.16 PVD26245.1 - 3.9e-09 36.7 26.1 7e-06 26.1 2.7 3.5 1 1 2 3 3 3 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 PVD26245.1 - 1.6e-05 24.6 1.6 1.6e-05 24.6 1.6 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD26245.1 - 3e-05 23.8 1.7 3e-05 23.8 1.7 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD26245.1 - 5.2e-05 23.3 0.9 5.2e-05 23.3 0.9 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 PVD26245.1 - 6.9e-05 23.2 29.6 0.0034 17.8 13.6 3.8 2 1 2 4 4 4 2 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 PVD26245.1 - 0.00073 19.5 4.6 0.00073 19.5 4.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD26245.1 - 0.0035 17.6 2.9 0.0035 17.6 2.9 3.7 2 1 1 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD26245.1 - 0.0058 16.6 3.0 0.0058 16.6 3.0 3.6 3 0 0 3 3 3 1 zinc-RING finger domain U-box PF04564.15 PVD26245.1 - 0.097 12.9 0.2 2.1 8.6 0.0 3.0 3 0 0 3 3 3 0 U-box domain NPV_P10 PF05531.12 PVD26245.1 - 0.13 12.7 2.0 16 6.0 0.2 2.9 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MATH PF00917.26 PVD26245.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.9 1 1 0 1 1 1 0 MATH domain Spc24 PF08286.11 PVD26245.1 - 0.91 9.8 3.6 0.63 10.3 0.7 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.9 PVD26245.1 - 3.2 8.0 9.6 6.4 7.0 9.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 zf-TRAF PF02176.18 PVD26246.1 - 4.2e-14 53.0 37.2 3.8e-09 37.1 4.9 4.3 2 1 2 4 4 4 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 PVD26246.1 - 7.8e-06 26.3 35.4 0.007 16.8 9.3 4.1 3 1 1 4 4 4 3 TRAF-like zinc-finger Sina PF03145.16 PVD26246.1 - 0.00053 20.0 31.1 0.036 14.0 8.4 4.1 2 1 2 4 4 4 2 Seven in absentia protein family Laminin_II PF06009.12 PVD26246.1 - 0.0049 16.9 3.8 0.0087 16.1 3.8 1.4 1 0 0 1 1 1 1 Laminin Domain II HIP1_clath_bdg PF16515.5 PVD26246.1 - 0.041 14.5 8.1 0.083 13.5 8.1 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MATH PF00917.26 PVD26246.1 - 0.18 12.0 0.8 1.1 9.4 0.0 2.6 3 1 0 3 3 3 0 MATH domain DUF3584 PF12128.8 PVD26246.1 - 0.2 9.1 10.9 0.27 8.7 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) THP2 PF09432.10 PVD26246.1 - 0.27 11.3 1.4 0.47 10.5 1.4 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 PAS PF00989.25 PVD26246.1 - 0.5 10.4 3.6 0.65 10.0 2.0 2.0 1 1 1 2 2 2 0 PAS fold FlaC_arch PF05377.11 PVD26246.1 - 0.6 10.5 2.7 9.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 PVD26246.1 - 0.63 10.6 7.9 1.3 9.6 7.2 2.0 2 1 0 2 2 1 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 PVD26246.1 - 0.94 9.6 9.5 1.8 8.7 9.5 1.4 1 0 0 1 1 1 0 Tropomyosin like Seryl_tRNA_N PF02403.22 PVD26246.1 - 1.1 9.5 4.5 2 8.7 4.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 PVD26246.1 - 1.7 9.0 7.0 1.3e+02 3.0 0.0 3.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 PVD26246.1 - 1.7 8.7 5.9 3.7 7.6 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CLZ PF16526.5 PVD26246.1 - 2.4 8.6 5.0 9.1 6.7 5.0 2.0 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spectrin PF00435.21 PVD26246.1 - 2.4 8.7 9.0 6.9 7.2 9.0 1.7 1 0 0 1 1 1 0 Spectrin repeat DUF724 PF05266.14 PVD26246.1 - 4.9 6.9 7.4 8.7 6.1 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 PVD26246.1 - 6.5 7.0 6.6 40 4.5 6.6 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 zf-ACC PF17848.1 PVD26246.1 - 7.6 6.7 17.2 1.8 8.7 0.2 4.8 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain UPF0242 PF06785.11 PVD26246.1 - 7.6 6.6 10.8 12 5.9 10.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EF-hand_8 PF13833.6 PVD26248.1 - 1.6e-08 34.3 0.7 5e-08 32.7 0.7 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 PVD26248.1 - 2.1e-08 34.5 0.3 2.1e-08 34.5 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD26248.1 - 3.4e-07 29.3 0.3 1.1e-06 27.8 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 PVD26248.1 - 1.1e-05 24.7 0.2 2.6e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PVD26248.1 - 1.3e-05 24.7 0.5 0.00015 21.4 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PVD26248.1 - 0.22 11.5 3.0 0.51 10.3 0.1 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Gal-3-0_sulfotr PF06990.11 PVD26249.1 - 9.4e-33 113.7 4.2 6.3e-21 74.7 0.7 2.0 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD26249.1 - 0.0084 16.0 2.0 0.013 15.5 2.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Ribosomal_S27e PF01667.17 PVD26249.1 - 0.07 12.9 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 Thg1C PF14413.6 PVD26249.1 - 0.099 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain Gal-3-0_sulfotr PF06990.11 PVD26250.1 - 1.5e-49 169.0 5.0 4.9e-49 167.3 5.0 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Ribosomal_S27e PF01667.17 PVD26250.1 - 0.052 13.3 1.0 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Thg1C PF14413.6 PVD26250.1 - 0.1 12.7 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 Thg1 C terminal domain Claudin_3 PF06653.11 PVD26251.1 - 3.1e-05 24.0 16.8 4.9e-05 23.3 16.8 1.3 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 PVD26251.1 - 0.0042 16.9 16.7 0.056 13.2 11.3 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 PVD26251.1 - 0.1 12.1 0.2 0.1 12.1 0.2 2.3 1 1 1 2 2 2 0 Clc-like DUF1179 PF06678.11 PVD26251.1 - 0.89 9.6 2.0 2.6 8.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) DUF3566 PF12089.8 PVD26251.1 - 2.3 8.6 10.4 0.083 13.2 3.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) DUF5090 PF17009.5 PVD26251.1 - 2.8 7.9 7.7 0.69 9.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Pkinase_Tyr PF07714.17 PVD26252.1 - 6.2e-62 209.2 0.1 8.4e-62 208.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD26252.1 - 4.1e-24 85.4 0.0 5.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PVD26252.1 - 0.0015 17.5 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PVD26252.1 - 0.056 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PVD26252.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DUF5063 PF16702.5 PVD26252.1 - 0.16 12.4 0.1 0.24 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Pkinase_Tyr PF07714.17 PVD26253.1 - 1.6e-23 83.4 0.0 2.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD26253.1 - 6.6e-15 55.2 0.0 1.4e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_red_sm PF00268.21 PVD26253.1 - 0.0035 16.8 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TMEM190 PF15431.6 PVD26253.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 DUF3040 PF11239.8 PVD26254.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) APH_6_hur PF04655.14 PVD26255.1 - 0.074 12.4 0.0 0.083 12.3 0.0 1.0 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fe-S_biosyn PF01521.20 PVD26257.1 - 2.2e-15 56.8 0.0 3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF4594 PF15266.6 PVD26262.1 - 5e-13 49.8 13.9 5e-13 49.8 13.9 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4594) PAM2 PF07145.15 PVD26262.1 - 0.051 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF745 PF05335.13 PVD26265.1 - 0.00017 21.4 12.9 0.00017 21.4 12.9 6.3 5 1 1 6 6 6 4 Protein of unknown function (DUF745) KELK PF15796.5 PVD26265.1 - 0.00091 19.6 8.1 0.00091 19.6 8.1 12.3 2 2 10 14 14 14 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 PVD26265.1 - 0.0014 18.6 19.3 0.0014 18.6 19.3 9.4 3 2 7 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 PVD26265.1 - 0.0042 16.0 22.5 0.0042 16.0 22.5 7.6 3 2 6 9 9 9 3 Spc7 kinetochore protein YqjK PF13997.6 PVD26265.1 - 3.1 8.1 8.9 2.9 8.2 0.5 3.8 3 0 0 3 3 3 0 YqjK-like protein ResIII PF04851.15 PVD26266.1 - 1.1e-18 67.8 4.7 1.6e-18 67.3 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD26266.1 - 2.8e-17 63.0 0.1 3.8e-16 59.3 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Spt5_N PF11942.8 PVD26266.1 - 0.59 11.2 18.4 0.045 14.7 1.6 4.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4497 PF14924.6 PVD26267.1 - 6e-22 78.1 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) HPHLAWLY PF14925.6 PVD26268.1 - 0.00013 20.9 15.5 0.00013 20.9 15.5 3.7 2 2 1 3 3 3 2 Domain of unknown function SpoU_methylase PF00588.19 PVD26269.1 - 5e-26 91.6 0.0 1.2e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family SH3_9 PF14604.6 PVD26270.1 - 5.6e-08 32.5 0.0 1.7e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.9 PVD26270.1 - 1.2e-05 25.2 0.1 0.00054 19.8 0.1 2.4 1 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase SH3_2 PF07653.17 PVD26270.1 - 0.016 14.8 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain DivIC PF04977.15 PVD26270.1 - 0.023 14.5 6.8 1.9 8.3 0.1 3.8 3 1 1 4 4 4 0 Septum formation initiator Spore_III_AB PF09548.10 PVD26270.1 - 0.074 13.2 1.8 0.36 10.9 1.9 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SH3_1 PF00018.28 PVD26270.1 - 0.076 12.6 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 SH3 domain DUF4191 PF13829.6 PVD26270.1 - 0.11 11.8 3.0 0.87 8.9 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) Uds1 PF15456.6 PVD26270.1 - 0.34 11.1 11.6 0.92 9.7 9.5 2.6 2 1 0 2 2 2 0 Up-regulated During Septation Cob_adeno_trans PF01923.18 PVD26270.1 - 0.56 10.3 2.7 0.67 10.1 1.7 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF2203 PF09969.9 PVD26270.1 - 1.2 9.9 6.8 1.1 10.0 3.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) RBB1NT PF08169.11 PVD26271.1 - 1.4e-23 82.9 0.0 8.9e-23 80.3 0.0 2.6 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.21 PVD26271.1 - 8.6e-23 80.8 0.7 1.5e-22 80.1 0.1 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 PVD26271.1 - 3e-12 46.2 0.8 1e-11 44.5 0.8 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain TUDOR_5 PF18359.1 PVD26271.1 - 0.037 13.7 0.8 7.9 6.3 0.0 3.1 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 Tudor_2 PF18104.1 PVD26271.1 - 0.17 11.6 1.1 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Glyoxalase PF00903.25 PVD26272.1 - 9.5e-19 67.9 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PVD26272.1 - 3.3e-05 24.1 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PVD26272.1 - 0.0049 17.6 0.0 0.0067 17.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain AAA_6 PF12774.7 PVD26273.1 - 2.6e-155 516.3 0.0 8e-154 511.5 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD26273.1 - 2.6e-134 448.3 4.5 2.6e-134 448.3 4.5 3.3 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD26273.1 - 1.2e-92 310.0 2.8 1.7e-92 309.5 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PVD26273.1 - 7.5e-92 307.8 0.8 2.8e-91 306.0 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD26273.1 - 2e-80 269.1 3.8 1.6e-79 266.1 1.0 3.6 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PVD26273.1 - 4.6e-52 176.1 0.1 1.3e-50 171.5 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 PVD26273.1 - 2.9e-50 170.3 5.6 6.4e-29 100.8 0.0 6.8 5 1 0 5 5 5 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 PVD26273.1 - 5.1e-41 139.5 0.0 7.8e-39 132.5 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD26273.1 - 8e-37 127.0 3.6 1.6e-36 126.1 3.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 PVD26273.1 - 1.1e-14 54.4 0.1 4.4e-14 52.5 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD26273.1 - 1.8e-14 53.9 2.1 0.016 15.2 0.0 7.7 6 2 0 6 6 6 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD26273.1 - 1.2e-13 51.8 1.2 3.9e-05 24.1 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain Dynein_AAA_lid PF17852.1 PVD26273.1 - 1.9e-12 47.4 0.0 7.2e-11 42.3 0.0 3.6 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PVD26273.1 - 1.4e-09 38.5 1.7 0.11 12.9 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD26273.1 - 1.4e-08 35.1 3.8 0.047 14.0 0.1 5.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 PVD26273.1 - 3.3e-07 30.9 6.0 2.6 8.6 0.0 6.3 6 0 0 6 6 4 2 AAA domain RNA_helicase PF00910.22 PVD26273.1 - 5.9e-07 29.8 0.3 1.3 9.5 0.1 4.9 4 0 0 4 4 4 2 RNA helicase Rad17 PF03215.15 PVD26273.1 - 4.2e-06 26.8 1.2 4.1 7.3 0.0 5.0 4 0 0 4 4 4 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 PVD26273.1 - 1.8e-05 24.7 1.5 0.039 13.9 0.3 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 PVD26273.1 - 2.6e-05 23.9 0.3 2.3 8.0 0.1 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD26273.1 - 5.9e-05 23.6 9.5 0.063 13.8 0.4 5.1 5 0 0 5 5 3 1 ABC transporter RuvB_N PF05496.12 PVD26273.1 - 0.00087 19.1 1.0 13 5.5 0.0 3.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 PVD26273.1 - 0.0011 18.7 4.4 5.4 6.7 0.1 4.6 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 PVD26273.1 - 0.0012 19.0 3.1 24 5.1 0.0 5.4 5 0 0 5 5 4 0 AAA domain Sigma54_activat PF00158.26 PVD26273.1 - 0.0028 17.4 3.1 0.92 9.2 0.1 3.9 4 0 0 4 4 4 1 Sigma-54 interaction domain T2SSE PF00437.20 PVD26273.1 - 0.0034 16.5 2.4 0.76 8.8 0.0 3.6 4 0 0 4 4 3 1 Type II/IV secretion system protein TsaE PF02367.17 PVD26273.1 - 0.0075 16.3 5.8 1.3 9.1 0.1 4.4 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PVD26273.1 - 0.0078 16.6 5.5 0.35 11.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 PVD26273.1 - 0.0099 15.1 4.0 2 7.5 0.0 3.6 5 0 0 5 5 5 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PVD26273.1 - 0.085 12.2 8.9 0.42 10.0 0.0 4.2 5 0 0 5 5 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 PVD26273.1 - 0.14 11.5 2.8 7.1 5.9 0.0 3.9 4 0 0 4 4 4 0 Zeta toxin FtsK_SpoIIIE PF01580.18 PVD26273.1 - 0.18 11.1 0.9 4.1 6.7 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.6 PVD26273.1 - 0.47 10.2 6.1 25 4.5 0.1 4.1 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 PVD26273.1 - 1 9.6 5.0 0.88 9.8 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF745 PF05335.13 PVD26273.1 - 3.3 7.4 13.4 6.8 6.4 2.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Histone_H2A_C PF16211.5 PVD26274.1 - 1.8e-15 56.4 1.4 4.2e-15 55.2 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone_H2A_C PF16211.5 PVD26275.1 - 5.2e-21 74.1 1.1 1e-20 73.1 1.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PVD26275.1 - 1.6e-15 57.6 0.0 2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD26275.1 - 9.9e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PVD26276.1 - 9.6e-25 87.5 1.1 1.2e-24 87.2 1.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD26276.1 - 7.6e-07 29.3 0.7 1.8e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PVD26276.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 PVD26276.1 - 0.0031 17.6 0.2 0.0038 17.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-T_C PF15511.6 PVD26277.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 PVD26277.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PVD26277.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 PVD26277.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD26277.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PVD26277.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PVD26277.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 PVD26277.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF547 PF04784.14 PVD26278.1 - 4e-18 65.6 0.0 2.1e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF547 FYVE PF01363.21 PVD26278.1 - 3.1e-15 56.0 12.2 3.1e-15 56.0 12.2 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 PVD26278.1 - 0.29 11.4 6.0 1.6 8.9 6.0 2.3 1 0 0 1 1 1 0 FYVE-type zinc finger Pkinase PF00069.25 PVD26279.1 - 6.4e-64 215.9 0.1 1e-63 215.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26279.1 - 2.4e-39 135.2 0.0 3.5e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD26279.1 - 5.5e-07 29.2 0.0 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PVD26279.1 - 0.00017 20.7 0.1 0.00036 19.6 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD26279.1 - 0.028 14.4 0.5 0.12 12.3 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3552 PF12072.8 PVD26279.1 - 0.072 12.5 10.4 0.12 11.8 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) GCR1_C PF12550.8 PVD26279.1 - 1.8 8.9 6.0 0.35 11.2 1.9 1.9 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes PPR_2 PF13041.6 PVD26280.1 - 8.2e-26 89.9 0.3 1.5e-08 34.7 0.0 8.6 7 1 2 9 9 8 4 PPR repeat family PPR_3 PF13812.6 PVD26280.1 - 1.3e-21 76.4 4.6 2e-08 34.2 0.0 7.3 6 1 2 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 PVD26280.1 - 5e-17 60.9 6.1 0.012 15.8 0.0 10.5 11 0 0 11 11 10 3 PPR repeat PPR_1 PF12854.7 PVD26280.1 - 4.8e-14 51.8 0.0 9.8e-07 28.4 0.0 6.3 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 PVD26280.1 - 2.7e-13 49.8 0.0 5.4e-06 25.9 0.0 3.6 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_6 PF13174.6 PVD26280.1 - 5.2e-08 33.0 0.6 0.027 15.1 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26280.1 - 1.2e-06 28.9 7.5 1 9.9 0.2 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat SPO22 PF08631.10 PVD26280.1 - 4.7e-05 23.0 1.5 0.026 14.0 0.4 3.6 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 PVD26280.1 - 0.00064 20.3 0.4 34 5.6 0.0 7.0 7 1 1 8 8 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 PVD26280.1 - 0.0058 17.1 0.1 0.038 14.5 0.1 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4810) YfiO PF13525.6 PVD26280.1 - 0.028 14.1 0.7 0.073 12.8 0.7 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein Wzy_C_2 PF11846.8 PVD26280.1 - 0.081 12.8 1.3 40 4.1 0.0 3.9 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 PVD26280.1 - 0.19 12.1 2.0 31 5.0 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-G-binding_N PF07299.11 PVD26280.1 - 1 9.9 4.0 24 5.5 0.0 4.3 5 0 0 5 5 4 0 Elongation factor G-binding protein, N-terminal TPR_8 PF13181.6 PVD26280.1 - 1.7 9.1 5.2 19 5.8 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_1 PF01344.25 PVD26281.1 - 9.6e-40 133.9 9.8 1.7e-15 56.3 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 PVD26281.1 - 2.5e-25 88.2 8.1 2.4e-09 37.1 0.0 5.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD26281.1 - 5.8e-25 86.7 8.5 1.7e-10 40.8 0.0 4.7 3 1 2 5 5 5 4 Kelch motif Kelch_2 PF07646.15 PVD26281.1 - 4.1e-21 74.1 4.5 8.7e-08 31.9 0.4 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PVD26281.1 - 2.2e-17 62.8 6.2 7.8e-09 35.6 0.1 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD26281.1 - 1.4e-14 53.7 2.9 0.001 19.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif DSPc PF00782.20 PVD26284.1 - 1.8e-42 144.3 0.2 2.9e-42 143.6 0.2 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 PVD26284.1 - 1e-14 55.0 0.3 1.1e-10 41.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain PTPlike_phytase PF14566.6 PVD26284.1 - 2.6e-07 30.9 0.0 4.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PVD26284.1 - 0.00085 19.0 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase OST_P2 PF18235.1 PVD26284.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain PgaPase_1 PF06162.12 PVD26285.1 - 0.0063 16.3 0.9 0.015 15.1 0.9 1.6 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 UCH PF00443.29 PVD26286.1 - 2.3e-40 138.7 1.0 2.3e-40 138.7 1.0 2.6 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD26286.1 - 3.1e-26 92.7 3.4 3.1e-26 92.7 3.4 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 PVD26286.1 - 0.0038 17.4 0.1 8.9 6.9 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat DUF2019 PF09450.10 PVD26286.1 - 0.047 13.6 0.1 0.64 10.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) DUF2841 PF11001.8 PVD26286.1 - 0.056 13.5 0.1 0.056 13.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2841) DUF3464 PF11947.8 PVD26286.1 - 0.44 10.3 1.4 1.3 8.8 1.4 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AHSA1 PF08327.11 PVD26287.1 - 4.4e-20 72.2 0.0 9.1e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.11 PVD26287.1 - 1.5e-07 31.7 2.2 0.0025 18.0 0.1 2.4 1 1 1 2 2 2 2 Activator of Hsp90 ATPase, N-terminal Cyclase PF04199.13 PVD26287.1 - 0.17 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative cyclase LRR_6 PF13516.6 PVD26287.1 - 0.19 11.8 0.0 0.51 10.5 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeat Histone PF00125.24 PVD26289.1 - 3.5e-40 137.4 0.0 5.4e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 PVD26289.1 - 0.0024 18.2 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PVD26289.1 - 0.0081 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TPR_14 PF13428.6 PVD26290.1 - 1.2e-12 47.5 4.5 0.12 13.2 0.1 7.0 4 1 3 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 PVD26290.1 - 1.2e-05 25.5 0.4 1.2e-05 25.5 0.4 4.0 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 PVD26290.1 - 4.1e-05 24.0 0.3 0.53 10.8 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26290.1 - 0.00016 21.5 6.0 4.5 7.6 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD26290.1 - 0.0013 18.7 13.5 1.3 9.0 1.3 5.5 5 2 0 5 5 5 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 PVD26290.1 - 0.0013 19.3 1.4 0.074 13.7 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD26290.1 - 0.0015 18.8 5.2 1.3 9.4 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 PVD26290.1 - 0.014 14.6 16.5 0.045 12.9 0.6 4.9 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 PVD26290.1 - 0.018 15.6 6.0 28 5.6 0.1 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Pex14_N PF04695.13 PVD26290.1 - 0.02 15.5 4.9 0.042 14.5 0.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2_12 PF18658.1 PVD26290.1 - 0.021 14.4 0.3 0.057 13.0 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type TPR_8 PF13181.6 PVD26290.1 - 0.074 13.3 3.0 3.8 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 PVD26290.1 - 0.27 12.0 2.0 12 6.9 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26290.1 - 0.55 10.4 5.7 31 4.9 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3391 PF11871.8 PVD26290.1 - 1.2 9.7 4.8 6.2 7.4 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) CCDC85 PF10226.9 PVD26292.1 - 3.3e-64 216.1 8.7 4.5e-64 215.7 8.7 1.1 1 0 0 1 1 1 1 CCDC85 family ZapB PF06005.12 PVD26292.1 - 0.098 13.1 4.1 8 7.0 0.4 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 PVD26292.1 - 0.18 11.4 1.6 0.22 11.0 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rabaptin PF03528.15 PVD26292.1 - 0.85 8.3 8.5 2 7.0 1.4 2.2 1 1 1 2 2 2 0 Rabaptin DivIC PF04977.15 PVD26292.1 - 2.4 8.0 5.7 4.2 7.2 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator GTP_cyclohydroI PF01227.22 PVD26293.1 - 1.9e-56 190.3 0.1 2.2e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 PVD26293.1 - 0.059 13.5 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 QueF-like protein Glyco_hydro_18 PF00704.28 PVD26294.1 - 7.2e-63 213.2 0.0 9.4e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD26294.1 - 5.8e-07 29.6 1.1 9.7e-07 28.9 1.1 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF4849 PF16141.5 PVD26294.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 PMP22_Claudin PF00822.20 PVD26296.1 - 7.2e-06 26.0 13.1 1.2e-05 25.3 12.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD26296.1 - 5.4 6.7 21.3 4e+03 -2.6 21.3 2.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IFT43 PF15305.6 PVD26297.1 - 1.3e-41 142.0 3.4 1.3e-41 142.0 3.4 1.4 2 0 0 2 2 2 1 Intraflagellar transport protein 43 IQ PF00612.27 PVD26298.1 - 0.013 15.2 3.0 0.015 15.1 0.8 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Herpes_capsid PF06112.11 PVD26298.1 - 0.15 12.1 0.4 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GDWWSH PF15667.5 PVD26299.1 - 9e-13 48.2 0.5 1.2e-12 47.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function with motif GDWWSH Ank_2 PF12796.7 PVD26300.1 - 1.1e-55 186.1 8.6 7.1e-15 55.4 0.0 6.4 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD26300.1 - 4.3e-33 113.3 11.1 3e-07 30.8 0.0 8.2 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26300.1 - 2e-31 104.5 6.3 0.00043 20.5 0.0 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD26300.1 - 1.6e-26 92.0 11.6 6.7e-08 32.7 0.1 8.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD26300.1 - 2.6e-26 90.8 9.6 1.7e-05 25.1 0.1 8.3 6 1 2 8 8 8 6 Ankyrin repeat SOCS_box PF07525.16 PVD26300.1 - 0.00018 21.8 0.5 0.00056 20.2 0.1 2.1 2 0 0 2 2 2 1 SOCS box SART-1 PF03343.13 PVD26301.1 - 7.3e-138 460.9 29.9 7.3e-138 460.9 29.9 2.2 2 1 0 2 2 2 1 SART-1 family DUF4862 PF16154.5 PVD26301.1 - 0.0012 18.3 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4862) DUF445 PF04286.12 PVD26301.1 - 3.4 7.4 9.3 1.1 9.0 5.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) zf-TRAF PF02176.18 PVD26302.1 - 0.00011 22.8 6.4 0.0023 18.6 0.7 2.8 1 1 1 2 2 2 2 TRAF-type zinc finger ATG16 PF08614.11 PVD26302.1 - 0.00022 21.5 1.1 0.00032 21.0 1.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Sina PF03145.16 PVD26302.1 - 0.00094 19.2 0.3 0.0015 18.5 0.3 1.3 1 0 0 1 1 1 1 Seven in absentia protein family APG6_N PF17675.1 PVD26302.1 - 0.0032 18.0 0.6 0.0053 17.3 0.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region zf_UBZ PF18439.1 PVD26302.1 - 0.0038 16.8 0.5 1.4 8.6 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Macoilin PF09726.9 PVD26302.1 - 0.025 13.2 0.5 0.033 12.8 0.5 1.1 1 0 0 1 1 1 0 Macoilin family Mod_r PF07200.13 PVD26302.1 - 0.055 13.6 0.7 0.13 12.3 0.9 1.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 PVD26302.1 - 0.06 13.8 0.5 0.095 13.1 0.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) OmpH PF03938.14 PVD26302.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 PVD26302.1 - 0.097 13.1 2.4 0.22 12.0 2.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Fe_hyd_SSU PF02256.17 PVD26302.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Iron hydrogenase small subunit Zn-ribbon_8 PF09723.10 PVD26302.1 - 0.36 11.0 8.1 19 5.5 0.1 3.6 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 PVD26302.1 - 3.5 7.7 8.4 2.7 8.1 5.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Kelch_6 PF13964.6 PVD26303.1 - 4e-42 141.2 4.7 3.5e-10 39.8 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD26303.1 - 1.1e-38 129.7 10.4 2.8e-07 30.2 0.1 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PVD26303.1 - 3.2e-35 119.5 9.6 1.2e-09 37.5 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PVD26303.1 - 1e-33 115.0 10.9 1.5e-07 31.5 0.1 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD26303.1 - 1.9e-33 114.2 10.8 7.1e-07 29.1 0.2 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD26303.1 - 2.9e-29 100.6 8.6 3.7e-05 23.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif DUF1668 PF07893.13 PVD26303.1 - 0.0032 16.9 2.0 0.0037 16.7 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) Lig_chan PF00060.26 PVD26304.1 - 2.4e-28 98.9 0.3 3.5e-28 98.3 0.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD26304.1 - 1.1e-19 70.7 0.0 2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD26304.1 - 2.3e-17 63.2 0.0 3.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SLAC1 PF03595.17 PVD26304.1 - 0.0051 16.1 2.8 0.0086 15.4 2.8 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Ion_trans_2 PF07885.16 PVD26304.1 - 0.096 12.7 4.4 0.24 11.4 4.4 1.7 1 0 0 1 1 1 0 Ion channel Homeodomain PF00046.29 PVD26305.1 - 2e-22 78.8 1.3 2e-22 78.8 1.3 1.8 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 PVD26305.1 - 7e-05 22.5 3.8 0.00017 21.3 3.8 1.6 1 0 0 1 1 1 1 OAR domain DAZAP2 PF11029.8 PVD26305.1 - 0.18 12.7 2.0 0.54 11.2 2.0 1.8 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Metal_resist PF13801.6 PVD26305.1 - 2.8 8.2 7.6 3.8 7.7 0.6 3.2 3 1 0 3 3 3 0 Heavy-metal resistance OAR PF03826.17 PVD26306.1 - 0.0022 17.7 1.9 0.0034 17.2 1.9 1.3 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 PVD26307.1 - 4.1e-13 49.0 0.3 7.3e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 Homeodomain DUF2477 PF10631.9 PVD26308.1 - 0.27 11.9 1.9 0.99 10.1 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2477) Dpy-30 PF05186.13 PVD26309.1 - 2.6e-18 65.4 1.5 1.6e-17 62.9 0.6 2.7 3 0 0 3 3 3 1 Dpy-30 motif ADK PF00406.22 PVD26309.1 - 6.7e-17 62.0 0.2 9.4e-12 45.3 0.1 3.1 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 PVD26309.1 - 5e-09 36.7 14.4 6.4e-05 23.4 0.2 3.6 2 1 1 3 3 2 2 AAA domain AAA_18 PF13238.6 PVD26309.1 - 4e-05 24.2 0.2 4e-05 24.2 0.2 3.6 2 1 1 3 3 2 1 AAA domain Hydin_ADK PF17213.3 PVD26309.1 - 0.0011 19.3 6.6 0.0035 17.7 0.3 3.2 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain ATP_bind_1 PF03029.17 PVD26309.1 - 0.0025 17.6 1.3 0.21 11.4 0.0 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 PVD26309.1 - 0.003 18.0 2.7 0.017 15.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PVD26309.1 - 0.0044 17.5 1.2 0.095 13.1 0.1 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PVD26309.1 - 0.015 15.4 0.4 0.058 13.6 0.0 2.2 3 0 0 3 3 1 0 AAA domain 6PF2K PF01591.18 PVD26309.1 - 0.032 13.5 0.0 0.032 13.5 0.0 2.6 3 0 0 3 3 3 0 6-phosphofructo-2-kinase SWIB PF02201.18 PVD26309.1 - 0.072 13.0 0.2 3.1 7.7 0.2 3.1 2 0 0 2 2 2 0 SWIB/MDM2 domain AAA_22 PF13401.6 PVD26309.1 - 0.085 13.1 2.2 2.4 8.4 0.0 3.6 2 2 1 3 3 3 0 AAA domain AAA_28 PF13521.6 PVD26309.1 - 0.089 13.0 0.1 0.089 13.0 0.1 2.5 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 PVD26309.1 - 0.41 10.4 3.0 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Caldesmon PF02029.15 PVD26309.1 - 0.61 8.8 29.7 0.96 8.1 29.7 1.2 1 0 0 1 1 1 0 Caldesmon AAA_14 PF13173.6 PVD26309.1 - 1 9.4 4.2 1.5 8.8 0.0 3.2 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 PVD26309.1 - 1 9.8 4.6 0.71 10.4 0.0 2.8 3 0 0 3 3 2 0 ABC transporter DUF1840 PF08895.11 PVD26309.1 - 3.3 8.1 17.8 4.3 7.7 4.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) MCU PF04678.13 PVD26309.1 - 7.7 6.6 10.9 1.7 8.7 4.2 2.7 3 0 0 3 3 2 0 Mitochondrial calcium uniporter WD-3 PF09765.9 PVD26310.1 - 1.4e-33 116.4 0.1 1.8e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 PVD26310.1 - 1e-28 99.3 4.6 1.8e-28 98.5 4.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 PVD26310.1 - 1.9e-05 24.9 8.2 8.8e-05 22.8 8.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 PVD26310.1 - 0.011 16.0 1.6 0.021 15.1 1.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Atracotoxin PF05353.11 PVD26310.1 - 0.012 15.6 1.8 0.024 14.7 1.8 1.5 1 0 0 1 1 1 0 Delta Atracotoxin zf-rbx1 PF12678.7 PVD26310.1 - 0.029 14.7 7.4 0.15 12.4 7.4 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 PVD26310.1 - 0.3 11.3 4.9 0.55 10.4 4.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 PVD26310.1 - 0.56 10.3 7.6 2.1 8.5 3.9 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 PVD26310.1 - 0.73 10.2 3.9 3 8.2 3.9 2.1 1 1 0 1 1 1 0 RING-like domain adh_short PF00106.25 PVD26311.1 - 5.9e-20 71.5 2.9 1.3e-14 54.1 0.1 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD26311.1 - 1.3e-10 41.3 1.0 7.2e-09 35.5 0.0 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 PVD26311.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Transformer PF06495.11 PVD26312.1 - 0.15 12.2 15.0 0.59 10.2 15.0 2.0 1 0 0 1 1 1 0 Fruit fly transformer protein Zw10 PF06248.13 PVD26313.1 - 1.7e-118 396.6 13.3 2.7e-118 395.9 13.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Plus-3 PF03126.18 PVD26314.1 - 3.6e-35 120.8 0.6 1.2e-34 119.1 0.1 2.2 2 0 0 2 2 2 1 Plus-3 domain SpoU_methylase PF00588.19 PVD26314.1 - 0.15 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 SpoU rRNA Methylase family FYVE PF01363.21 PVD26315.1 - 2.3e-28 98.1 24.7 3.6e-16 59.1 9.7 5.7 4 2 0 4 4 4 2 FYVE zinc finger GBP PF02263.19 PVD26315.1 - 0.00036 19.9 0.1 0.00061 19.1 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AIG1 PF04548.16 PVD26315.1 - 0.0021 17.4 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD26315.1 - 0.0025 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-B_box PF00643.24 PVD26315.1 - 0.0073 16.4 11.2 0.0073 16.4 11.2 7.6 9 0 0 9 9 9 3 B-box zinc finger IBR PF01485.21 PVD26315.1 - 0.016 15.5 3.5 0.016 15.5 3.5 6.2 7 0 0 7 7 7 0 IBR domain, a half RING-finger domain V-SNARE_C PF12352.8 PVD26316.1 - 1.9e-17 63.3 6.0 1.9e-17 63.3 6.0 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PVD26316.1 - 6.1e-16 58.6 4.4 6.1e-16 58.6 4.4 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 PVD26316.1 - 1.8e-06 27.8 1.2 1.8e-06 27.8 1.2 2.1 2 1 0 2 2 2 1 Sec20 V-ATPase_G_2 PF16999.5 PVD26316.1 - 0.00016 22.1 1.8 0.00016 22.1 1.8 2.0 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit LMBR1 PF04791.16 PVD26316.1 - 0.051 12.5 1.2 0.066 12.1 1.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S46 PF10459.9 PVD26316.1 - 0.16 10.5 3.6 0.12 10.9 2.4 1.3 1 1 0 1 1 1 0 Peptidase S46 WXG100 PF06013.12 PVD26316.1 - 0.39 11.0 5.4 12 6.2 0.1 3.7 2 2 2 4 4 4 0 Proteins of 100 residues with WXG SKA2 PF16740.5 PVD26316.1 - 0.39 10.5 6.9 1.9 8.3 0.7 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TMPIT PF07851.13 PVD26316.1 - 1.8 7.8 6.9 2.1 7.5 1.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein YojJ PF10372.9 PVD26316.1 - 3.5 7.8 5.4 31 4.8 0.0 3.6 3 2 2 5 5 5 0 Bacterial membrane-spanning protein N-terminus CCDC-167 PF15188.6 PVD26316.1 - 3.5 8.0 13.7 1.1 9.7 0.4 3.7 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF883 PF05957.13 PVD26316.1 - 4 8.1 9.9 5.2 7.8 0.6 3.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Glyco_transf_43 PF03360.16 PVD26317.1 - 2.3e-73 246.4 0.0 3.2e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 AMP-binding PF00501.28 PVD26318.1 - 1.1e-54 185.7 0.0 1.4e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD26318.1 - 4e-10 40.5 0.0 1.5e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 PVD26319.1 - 6.6e-95 318.7 0.1 8e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 Amidase HEAT_2 PF13646.6 PVD26321.1 - 1.1e-11 45.0 16.7 0.026 14.9 0.1 8.2 8 1 0 8 8 8 4 HEAT repeats HEAT PF02985.22 PVD26321.1 - 2e-09 36.9 29.1 0.34 11.3 0.3 9.6 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.6 PVD26321.1 - 4.3e-06 27.1 20.5 1.7 9.2 0.2 9.1 9 1 0 9 9 9 3 HEAT-like repeat Cnd1 PF12717.7 PVD26321.1 - 0.0072 16.4 1.0 2 8.5 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 PVD26321.1 - 0.066 12.8 8.2 8.4 5.9 0.4 4.3 3 0 0 3 3 3 0 CLASP N terminal Sigma70_ner PF04546.13 PVD26321.1 - 0.23 11.3 0.5 17 5.2 0.3 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region RTP1_C1 PF10363.9 PVD26321.1 - 0.52 10.5 3.1 66 3.7 0.0 5.3 5 2 1 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 PVD26321.1 - 2.7 6.4 16.8 0.72 8.3 0.2 4.5 5 0 0 5 5 5 0 Adaptin N terminal region Arm PF00514.23 PVD26321.1 - 9.5 6.4 17.4 0.72 10.0 0.9 6.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TatD_DNase PF01026.21 PVD26322.1 - 5.6e-59 199.6 0.3 6.4e-59 199.4 0.3 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 PVD26322.1 - 0.019 14.3 0.8 0.77 9.0 0.3 2.1 1 1 1 2 2 2 0 Amidohydrolase family Mis14 PF08641.12 PVD26323.1 - 2.9e-06 27.6 2.3 3.2e-06 27.5 0.6 2.0 2 1 0 2 2 2 1 Kinetochore protein Mis14 like DUF4820 PF16091.5 PVD26326.1 - 0.1 11.9 1.7 0.12 11.8 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol_E_B PF04042.16 PVD26327.1 - 3.2e-49 167.1 0.3 4.7e-49 166.6 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 PVD26327.1 - 2.9e-28 98.0 0.1 5.1e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF4549 PF15082.6 PVD26327.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) NumbF PF06311.12 PVD26328.1 - 1.4e-32 112.1 4.2 1.2e-31 109.1 0.4 3.0 2 0 0 2 2 2 1 NUMB domain PID PF00640.23 PVD26328.1 - 1.7e-23 83.2 0.3 3.6e-23 82.2 0.3 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 PVD26328.1 - 0.0022 17.9 0.1 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD26328.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain HEAT PF02985.22 PVD26330.1 - 3e-10 39.5 6.1 0.38 11.1 0.0 7.7 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 PVD26330.1 - 0.0005 20.4 1.7 0.75 10.2 0.0 4.3 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 PVD26330.1 - 0.078 13.5 0.2 34 5.1 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat zf-C2H2 PF00096.26 PVD26331.1 - 5.3e-07 29.8 24.9 0.0017 18.7 3.3 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD26331.1 - 1.7e-05 25.0 19.4 0.002 18.5 0.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 PVD26331.1 - 0.00058 19.6 7.5 0.003 17.3 1.9 2.9 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PVD26331.1 - 0.00082 20.0 17.4 0.025 15.4 1.9 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 PVD26331.1 - 0.0019 18.5 16.5 0.25 11.8 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type GLTSCR1 PF15249.6 PVD26331.1 - 0.39 11.2 4.2 0.38 11.2 0.5 3.1 2 1 1 3 3 3 0 Conserved region of unknown function on GLTSCR protein zf-trcl PF13451.6 PVD26331.1 - 0.63 10.0 3.3 17 5.4 0.2 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain DUF3585 PF12130.8 PVD26332.1 - 8.5e-39 132.8 24.4 8.5e-39 132.8 24.4 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 PVD26332.1 - 7.4e-26 90.5 0.0 1.4e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain NT-C2 PF10358.9 PVD26332.1 - 1.7e-13 50.6 0.4 4.7e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CAMSAP_CH PF11971.8 PVD26332.1 - 3.8e-06 26.6 0.0 9.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain DUF1843 PF08898.10 PVD26332.1 - 0.042 14.3 0.0 0.042 14.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Homeodomain PF00046.29 PVD26336.1 - 0.12 12.3 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Homeodomain PRIMA1 PF16101.5 PVD26336.1 - 0.61 10.1 4.7 1.1 9.3 4.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cu2_monoox_C PF03712.15 PVD26338.1 - 4.1e-25 88.1 0.5 1e-24 86.8 0.5 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD26338.1 - 5.3e-24 84.9 1.7 5.3e-24 84.9 1.7 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Homeodomain PF00046.29 PVD26339.1 - 6.5e-13 48.3 0.8 9.6e-13 47.8 0.8 1.2 1 0 0 1 1 1 1 Homeodomain Mito_carr PF00153.27 PVD26340.1 - 7.8e-37 125.1 0.1 8.8e-19 67.2 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein TT_ORF2a PF08197.11 PVD26340.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 pORF2a truncated protein CNH PF00780.22 PVD26341.1 - 9.6e-22 77.9 0.1 2.1e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 PVD26341.1 - 2.2e-20 72.9 8.3 1.1e-13 51.4 0.6 4.4 4 1 1 5 5 5 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 PVD26341.1 - 2.3e-12 47.3 0.7 7.8e-12 45.6 0.7 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 PVD26341.1 - 1.9e-05 24.6 17.9 0.11 12.4 2.6 5.2 3 2 1 4 4 4 3 Region in Clathrin and VPS TPR_12 PF13424.6 PVD26341.1 - 0.03 14.6 0.8 6.1 7.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Spectrin PF00435.21 PVD26345.1 - 7.2e-292 945.7 178.8 4.6e-25 88.1 4.8 17.7 17 1 0 17 17 17 17 Spectrin repeat CH PF00307.31 PVD26345.1 - 1.6e-45 153.7 8.2 4.7e-24 84.7 0.1 4.0 3 0 0 3 3 3 2 Calponin homology (CH) domain PH_9 PF15410.6 PVD26345.1 - 1.6e-18 67.2 0.1 1e-17 64.6 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 PVD26345.1 - 3e-13 50.2 0.1 5e-12 46.3 0.0 2.8 2 0 0 2 2 2 1 PH domain CAMSAP_CH PF11971.8 PVD26345.1 - 2.3e-07 30.6 0.1 2.7e-05 23.9 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain DUF5616 PF18481.1 PVD26345.1 - 0.014 15.8 3.4 3.5 8.0 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5616) CnrY PF17524.2 PVD26345.1 - 9.7 6.5 6.7 1.6e+02 2.6 0.0 4.4 4 0 0 4 4 4 0 Anti-sigma factor CnrY Myb_DNA-binding PF00249.31 PVD26346.1 - 1.6e-15 57.0 0.0 1.1e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELM2 PF01448.24 PVD26346.1 - 1.2e-12 48.4 0.1 4.4e-12 46.5 0.1 2.1 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 PVD26346.1 - 2.4e-06 27.3 0.3 0.081 12.8 0.1 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PVD26346.1 - 3.7e-05 23.9 0.3 0.011 16.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain GATA PF00320.27 PVD26346.1 - 0.037 13.6 3.4 0.11 12.1 3.4 1.9 1 1 0 1 1 1 0 GATA zinc finger MFMR_assoc PF16596.5 PVD26346.1 - 6.1 7.3 14.8 3.3 8.2 0.2 3.4 3 0 0 3 3 3 0 Disordered region downstream of MFMR DRY_EERY PF09750.9 PVD26347.1 - 2.9e-40 137.7 0.0 2.9e-40 137.7 0.0 3.7 4 0 0 4 4 4 1 Alternative splicing regulator Rap_GAP PF02145.15 PVD26348.1 - 1.7e-68 229.8 0.3 2.7e-68 229.2 0.3 1.3 1 0 0 1 1 1 1 Rap/ran-GAP SPAR_C PF11881.8 PVD26348.1 - 4.5e-23 82.4 2.0 4.5e-23 82.4 2.0 2.2 2 0 0 2 2 2 1 C-terminal domain of SPAR protein PDZ PF00595.24 PVD26348.1 - 7.8e-06 26.2 0.1 2.3e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD26348.1 - 0.0004 20.2 0.1 0.0009 19.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Jnk-SapK_ap_N PF09744.9 PVD26348.1 - 0.079 13.2 2.8 0.25 11.5 2.8 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Retrotrans_gag PF03732.17 PVD26348.1 - 1.9 8.8 3.8 3 8.2 0.9 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Glycos_transf_2 PF00535.26 PVD26349.1 - 4.5e-27 94.9 0.1 6.9e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD26349.1 - 8.3e-20 71.3 0.4 1.6e-19 70.4 0.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 PVD26349.1 - 0.012 15.2 0.3 0.48 10.0 0.0 2.5 2 1 0 2 2 2 0 Cytolethal distending toxin A/C domain Glyco_tranf_2_2 PF10111.9 PVD26349.1 - 0.019 14.4 0.1 0.03 13.8 0.1 1.4 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Pecanex_C PF05041.15 PVD26350.1 - 1.1e-32 113.4 0.0 2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF5117 PF17148.4 PVD26350.1 - 0.0073 16.2 1.1 0.014 15.3 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5117) Med17 PF10156.9 PVD26351.1 - 0.00017 20.4 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF2491 PF10679.9 PVD26351.1 - 0.07 12.3 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) CRM1_C PF08767.11 PVD26353.1 - 8.5e-133 442.5 5.6 8.5e-133 442.5 5.6 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 PVD26353.1 - 6.1e-43 146.4 14.0 1.5e-41 141.9 1.3 5.3 5 1 0 5 5 5 2 Exportin 1-like protein CRM1_repeat_3 PF18787.1 PVD26353.1 - 4e-24 84.5 0.1 3.1e-23 81.6 0.0 2.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 PVD26353.1 - 1.6e-18 65.9 1.4 3.4e-18 64.8 1.4 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 PVD26353.1 - 5.5e-12 45.4 3.0 7.6e-12 45.0 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 PVD26353.1 - 0.0034 17.9 5.5 2.6 8.7 0.1 5.7 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region zf-H2C2_2 PF13465.6 PVD26354.1 - 3.6e-24 84.1 25.4 1e-07 32.0 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD26354.1 - 8.2e-22 76.4 25.4 6.9e-06 26.2 0.1 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD26354.1 - 9.8e-16 57.1 25.7 0.0039 17.9 2.0 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD26354.1 - 1.4e-07 31.7 7.2 0.00025 21.3 1.7 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD26354.1 - 8.8e-05 22.7 6.1 7.9 6.9 0.0 4.8 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 PVD26354.1 - 0.00018 21.7 2.5 0.38 10.9 0.1 3.7 1 1 2 3 3 3 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 PVD26354.1 - 0.00054 19.9 17.8 0.4 10.7 2.3 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD26354.1 - 0.0014 18.8 3.1 1.1 9.7 0.1 2.9 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Rep_fac-A_C PF08646.10 PVD26354.1 - 0.0018 18.0 0.1 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain zf-C2HC_2 PF13913.6 PVD26354.1 - 0.013 15.4 0.1 0.013 15.4 0.1 4.9 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 PVD26354.1 - 0.085 12.6 13.7 0.31 10.8 1.1 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 PVD26354.1 - 0.2 12.1 11.3 0.2 12.1 0.5 3.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 PVD26354.1 - 0.27 10.9 4.1 9.3 5.9 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 PVD26354.1 - 2.2 8.5 5.0 9.6 6.5 0.2 3.4 3 0 0 3 3 3 0 HNH endonuclease zf-H2C2_5 PF13909.6 PVD26354.1 - 4.2 7.2 15.6 6.8 6.6 0.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Ribosomal_S5_C PF03719.15 PVD26355.1 - 1.3e-18 66.2 0.0 2.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 PVD26355.1 - 6.5e-18 64.5 0.2 1.4e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF3671 PF12420.8 PVD26356.1 - 0.093 12.8 0.6 0.19 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DEAD PF00270.29 PVD26357.1 - 2.3e-38 131.7 0.0 3.5e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD26357.1 - 5.4e-29 100.8 0.4 1e-27 96.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD26357.1 - 2.4e-07 30.9 0.4 8.2e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD26357.1 - 0.00019 21.8 0.0 0.00051 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD26357.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 PVD26357.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 PVD26357.1 - 0.17 12.2 0.2 2.9 8.2 0.2 2.6 1 1 0 1 1 1 0 AAA domain HCV_NS4a PF01006.20 PVD26358.1 - 0.39 10.5 2.4 0.55 10.0 2.4 1.4 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Spectrin PF00435.21 PVD26359.1 - 0.00026 21.4 29.8 0.005 17.3 4.2 5.0 4 1 1 5 5 5 3 Spectrin repeat P66_CC PF16563.5 PVD26359.1 - 0.28 10.8 1.9 0.91 9.2 1.9 1.9 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 adh_short PF00106.25 PVD26360.1 - 9.3e-105 348.3 12.8 1.6e-36 125.6 0.2 4.5 3 3 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PVD26360.1 - 8e-76 254.7 3.1 3e-25 89.1 0.0 4.5 3 3 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_65m PF03632.15 PVD26360.1 - 3e-42 144.9 0.3 1.1e-36 126.5 0.3 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain KR PF08659.10 PVD26360.1 - 1.2e-24 87.2 6.1 9.6e-08 32.1 0.1 3.4 3 0 0 3 3 3 3 KR domain Epimerase PF01370.21 PVD26360.1 - 3.9e-09 36.3 1.5 0.049 13.1 0.0 3.7 3 1 0 3 3 3 3 NAD dependent epimerase/dehydratase family Hpr_kinase_C PF07475.12 PVD26360.1 - 1.2e-06 28.1 3.8 0.54 9.8 0.1 3.5 3 0 0 3 3 3 3 HPr Serine kinase C-terminal domain NAD_binding_10 PF13460.6 PVD26360.1 - 6.4e-06 26.2 1.2 0.064 13.2 0.1 3.7 3 0 0 3 3 3 1 NAD(P)H-binding EAV_GS PF01309.18 PVD26360.1 - 1.4e-05 24.8 0.0 0.57 9.8 0.0 3.6 3 0 0 3 3 3 1 Equine arteritis virus small envelope glycoprotein Toprim_4 PF13662.6 PVD26360.1 - 0.0022 18.4 0.1 39 4.8 0.0 4.0 3 0 0 3 3 3 0 Toprim domain Glyco_transf_4 PF13439.6 PVD26360.1 - 0.0025 17.8 0.0 0.75 9.8 0.0 4.1 5 0 0 5 5 5 1 Glycosyltransferase Family 4 DUF4162 PF13732.6 PVD26360.1 - 0.035 14.8 4.6 10 6.9 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4162) Herpes_UL52 PF03121.15 PVD26360.1 - 0.043 13.8 0.3 12 6.0 0.1 2.6 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase Med21 PF11221.8 PVD26360.1 - 0.084 13.1 5.3 24 5.1 0.1 3.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex F420H2_quin_red PF04075.14 PVD26360.1 - 0.12 12.5 1.4 33 4.6 0.0 3.3 3 0 0 3 3 3 0 F420H(2)-dependent quinone reductase LDcluster4 PF18306.1 PVD26360.1 - 1.4 8.4 5.2 8.8 5.9 0.1 3.1 3 0 0 3 3 3 0 SLOG cluster4 family Pkinase PF00069.25 PVD26361.1 - 7.5e-111 369.7 0.0 4.3e-66 223.0 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26361.1 - 1.8e-46 158.5 0.0 9.3e-31 107.0 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_C PF00433.24 PVD26361.1 - 5e-09 36.7 0.1 1.8e-08 35.0 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 PVD26361.1 - 3.7e-08 32.6 0.9 1.3e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 PVD26361.1 - 1.3e-07 31.3 0.0 0.002 17.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PVD26361.1 - 0.0014 17.7 0.3 0.0028 16.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD26361.1 - 0.0098 15.8 2.3 16 5.3 0.0 3.9 3 2 2 5 5 5 2 Phosphotransferase enzyme family FTA2 PF13095.6 PVD26361.1 - 0.035 13.7 0.1 9.2 5.8 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 HOOK PF05622.12 PVD26363.1 - 8.6e-14 50.6 73.2 8.6e-14 50.6 73.2 7.2 3 2 3 6 6 6 4 HOOK protein KASH_CCD PF14662.6 PVD26363.1 - 3.9e-06 26.8 69.3 3.3e-05 23.8 44.4 10.7 1 1 8 9 9 9 3 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 PVD26363.1 - 0.0019 18.2 14.8 0.0019 18.2 14.8 12.8 3 2 11 14 14 14 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 PVD26363.1 - 0.0054 17.2 21.9 0.0054 17.2 21.9 14.8 4 3 9 14 14 14 5 Apg6 coiled-coil region CAP_N PF01213.19 PVD26365.1 - 0.11 12.0 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPR_2 PF07719.17 PVD26366.1 - 2.1e-22 77.4 12.5 2.1e-05 24.3 0.0 9.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26366.1 - 2.3e-19 67.9 7.6 0.0012 18.9 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD26366.1 - 5.9e-14 52.1 19.3 6.2e-05 23.2 0.6 5.6 5 0 0 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PVD26366.1 - 6.6e-14 51.0 18.2 0.00022 20.9 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26366.1 - 8.1e-14 51.9 14.4 0.064 13.8 0.0 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD26366.1 - 1.2e-12 47.5 17.7 0.035 14.9 0.0 10.2 9 1 2 11 11 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD26366.1 - 2.3e-12 46.4 7.0 0.00069 19.8 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD26366.1 - 4e-12 46.3 29.2 1.1e-05 25.6 0.0 8.8 7 3 4 11 11 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD26366.1 - 1.6e-10 41.4 3.3 0.2 12.4 0.0 7.2 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD26366.1 - 1.6e-07 30.8 0.2 0.023 14.4 0.0 5.7 3 1 2 5 5 5 2 TPR repeat TPR_9 PF13371.6 PVD26366.1 - 6.9e-06 26.1 3.7 0.023 14.8 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD26366.1 - 3.8e-05 23.4 16.7 0.7 9.9 0.0 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD26366.1 - 0.00014 22.2 6.6 3.7 8.4 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 PVD26366.1 - 0.00024 20.0 0.9 0.016 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_7 PF13176.6 PVD26366.1 - 0.00082 19.2 8.2 14 6.0 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 PVD26366.1 - 0.0013 19.2 8.2 5.9 7.8 0.2 6.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 PVD26366.1 - 0.0043 16.8 1.8 0.1 12.3 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat-like domain ChAPs PF09295.10 PVD26366.1 - 0.012 14.6 3.8 1.2 8.1 0.1 3.1 3 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 PVD26366.1 - 6.2 7.2 8.1 7.8 6.9 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Homeodomain PF00046.29 PVD26368.1 - 4.1e-19 68.2 2.2 7.8e-19 67.3 2.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD26368.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain YesK PF14150.6 PVD26369.1 - 0.25 11.6 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 YesK-like protein PRKCSH PF07915.13 PVD26370.1 - 5.5e-28 97.8 5.2 2.3e-13 51.0 0.2 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PVD26370.1 - 1.3e-05 25.0 0.1 0.079 12.6 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein MOZ_SAS PF01853.18 PVD26371.1 - 2e-85 284.9 0.7 3.2e-85 284.3 0.7 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PVD26371.1 - 2.1e-19 68.8 3.2 2.1e-19 68.8 3.2 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 PVD26371.1 - 1.1e-17 63.7 0.0 4.9e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PVD26371.1 - 0.00066 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD26371.1 - 0.0037 17.5 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3720 PF12517.8 PVD26371.1 - 0.038 14.9 2.3 0.068 14.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Agenet PF05641.12 PVD26371.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Agenet domain Glyco_hydro_10 PF00331.20 PVD26372.1 - 3.9e-31 108.4 0.1 8.1e-31 107.3 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26372.1 - 7.2e-13 49.0 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_10 PF00331.20 PVD26373.1 - 5.9e-53 180.1 0.1 7.9e-53 179.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26373.1 - 7.3e-22 78.1 0.2 7.3e-22 78.1 0.2 2.6 3 0 0 3 3 3 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26373.1 - 0.00077 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26374.1 - 8.5e-53 179.5 0.1 1.2e-52 179.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26374.1 - 4e-09 36.8 0.1 2.3e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26374.1 - 0.0005 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26375.1 - 4.9e-26 91.6 3.5 1.3e-21 77.1 2.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26375.1 - 2.8e-12 47.1 1.7 6.3e-12 45.9 0.0 2.3 3 0 0 3 3 3 1 Carbohydrate binding domain Glyco_hydro_10 PF00331.20 PVD26376.1 - 9e-45 153.2 8.4 5.1e-44 150.7 8.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26376.1 - 4.7e-13 49.6 0.9 4.4e-12 46.4 0.1 2.8 3 0 0 3 3 3 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26376.1 - 0.00089 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26377.1 - 1.3e-43 149.3 6.7 1.8e-43 148.9 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26377.1 - 9e-13 48.7 0.0 2.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_10 PF00331.20 PVD26378.1 - 3.4e-48 164.4 8.1 4.5e-48 164.0 8.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26378.1 - 1.6e-12 47.9 1.8 3.7e-12 46.7 0.1 2.5 3 0 0 3 3 3 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26378.1 - 7.8e-05 22.3 0.8 0.0001 21.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26379.1 - 1.3e-17 63.9 6.8 4.2e-08 32.7 4.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26379.1 - 2e-13 50.8 0.1 5.7e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26379.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26381.1 - 2.7e-07 30.1 0.2 6.9e-06 25.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.20 PVD26383.1 - 3.2e-47 161.2 0.2 5.9e-47 160.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26383.1 - 4e-28 98.4 2.8 1.8e-13 51.0 0.0 3.1 2 1 1 3 3 3 2 Carbohydrate binding domain IN_DBD_C PF00552.21 PVD26383.1 - 0.034 13.4 0.7 13 5.2 0.0 3.5 4 0 0 4 4 4 0 Integrase DNA binding domain Peptidase_M4_C PF02868.15 PVD26384.1 - 9.8e-29 100.4 0.1 2.3e-28 99.2 0.1 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26384.1 - 2.9e-20 73.3 1.2 2.6e-18 66.9 0.3 2.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 PVD26384.1 - 2.2e-08 33.8 2.1 0.0017 18.1 0.3 3.1 2 0 0 2 2 2 2 Fungalysin/Thermolysin Propeptide Motif DUF4198 PF10670.9 PVD26384.1 - 0.0029 18.0 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4198) LytB_WW PF18342.1 PVD26384.1 - 0.075 13.2 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain YtkA PF13115.6 PVD26384.1 - 0.095 13.3 0.7 14 6.4 0.1 2.4 2 0 0 2 2 2 0 YtkA-like DUF3410 PF11890.8 PVD26384.1 - 0.14 12.0 0.4 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) DUF2403 PF10290.9 PVD26384.1 - 0.16 12.4 0.0 34 5.0 0.0 3.2 3 0 0 3 3 3 0 Glycine-rich protein domain (DUF2403) Tubulin_3 PF14881.6 PVD26384.1 - 0.28 10.9 1.8 18 4.9 0.1 2.7 2 0 0 2 2 2 0 Tubulin domain Peptidase_M4_C PF02868.15 PVD26385.1 - 2.9e-27 95.6 0.1 5.1e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26385.1 - 2.5e-06 28.1 1.1 2.5e-06 28.1 1.1 2.3 2 1 1 3 3 3 1 Thermolysin metallopeptidase, catalytic domain DUF3410 PF11890.8 PVD26385.1 - 0.14 12.0 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Peptidase_M4_C PF02868.15 PVD26386.1 - 9.3e-27 93.9 0.3 1.8e-26 93.0 0.3 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26386.1 - 2.9e-24 86.2 0.3 9.5e-24 84.6 0.3 1.9 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 PVD26386.1 - 0.00012 21.8 0.1 0.00041 20.1 0.1 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4 PF01447.18 PVD26387.1 - 1.5e-19 71.0 0.1 2.5e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 PVD26387.1 - 8.2e-17 61.6 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4_C PF02868.15 PVD26388.1 - 6.3e-29 101.0 0.1 1.1e-28 100.2 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26388.1 - 3.2e-26 92.6 1.0 8e-26 91.3 0.2 2.1 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 PVD26388.1 - 0.0088 15.9 0.2 0.025 14.4 0.2 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 PVD26389.1 - 1.7e-58 197.2 1.5 1.8e-28 99.5 0.0 2.6 2 0 0 2 2 2 2 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26389.1 - 1.3e-48 165.2 2.0 2.6e-23 83.1 0.1 3.3 3 0 0 3 3 3 2 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 PVD26389.1 - 6.4e-14 51.5 1.0 1.1e-06 28.3 0.2 3.1 2 0 0 2 2 2 2 Fungalysin/Thermolysin Propeptide Motif DUF3410 PF11890.8 PVD26389.1 - 0.00033 20.4 0.1 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3410) APAF1_C PF17908.1 PVD26389.1 - 0.071 13.1 3.9 6.1 6.8 0.2 2.5 2 0 0 2 2 2 0 APAF-1 helical domain DUF4198 PF10670.9 PVD26389.1 - 0.16 12.4 0.2 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Peptidase_M4 PF01447.18 PVD26390.1 - 8.2e-24 84.8 0.1 1.5e-23 84.0 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 PVD26390.1 - 1.2e-06 28.5 0.0 3.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.13 PVD26390.1 - 2.4e-05 24.1 0.1 6.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 PVD26392.1 - 5.6e-29 101.2 0.3 1.4e-28 99.9 0.1 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PVD26392.1 - 3.6e-25 89.2 0.2 2e-24 86.7 0.1 2.3 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 PVD26392.1 - 0.024 14.5 0.1 0.062 13.1 0.1 1.7 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF3410 PF11890.8 PVD26392.1 - 0.11 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DUF5063 PF16702.5 PVD26393.1 - 0.054 13.9 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) CUB PF00431.20 PVD26394.1 - 2.7e-19 69.5 0.2 6e-19 68.4 0.2 1.6 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 PVD26394.1 - 0.042 13.6 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 CUB-like domain Ank_2 PF12796.7 PVD26395.1 - 1e-56 189.5 9.0 4.4e-16 59.2 1.9 5.9 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 PVD26395.1 - 5.7e-45 149.9 21.0 8.6e-08 32.3 0.0 11.5 11 1 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 PVD26395.1 - 3.2e-38 129.6 13.0 4.7e-07 30.2 1.0 8.8 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26395.1 - 6.1e-36 118.4 18.9 0.00021 21.5 0.0 12.1 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 PVD26395.1 - 2.4e-35 120.1 19.5 3e-08 33.7 0.0 8.5 6 2 3 9 9 9 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD26395.1 - 0.00021 21.6 0.9 0.00055 20.2 0.9 1.8 1 0 0 1 1 1 1 SOCS box DUF3447 PF11929.8 PVD26395.1 - 0.026 14.5 0.0 1.2 9.1 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Lant_dehydr_C PF14028.6 PVD26395.1 - 0.041 13.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term SPG48 PF14764.6 PVD26395.1 - 0.045 14.2 0.1 45 4.6 0.0 3.5 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking DUF4205 PF13898.6 PVD26395.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Pkinase PF00069.25 PVD26396.1 - 3.5e-25 88.9 0.0 1.1e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain CBFD_NFYB_HMF PF00808.23 PVD26396.1 - 8e-14 51.7 0.9 1.4e-13 50.9 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MIT PF04212.18 PVD26396.1 - 4.3e-12 45.9 0.4 1.1e-11 44.7 0.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 PVD26396.1 - 5.5e-11 42.5 0.5 2.7e-10 40.2 0.8 2.0 2 0 0 2 2 2 1 PX domain Pkinase_Tyr PF07714.17 PVD26396.1 - 3.7e-08 33.0 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Histone PF00125.24 PVD26396.1 - 0.00045 20.6 1.0 0.00045 20.6 1.0 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Kinase-like PF14531.6 PVD26396.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BBS2_Mid PF14783.6 PVD26397.1 - 8.5e-05 22.6 0.1 0.048 13.7 0.0 3.3 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 PVD26397.1 - 0.0012 17.9 0.2 0.035 13.1 0.1 2.3 2 0 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 PVD26397.1 - 0.0051 16.9 0.4 0.023 14.8 0.4 2.2 1 0 0 1 1 1 1 FG-GAP repeat WD40 PF00400.32 PVD26397.1 - 0.019 15.8 0.8 7.7 7.6 0.0 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat VCBS PF13517.6 PVD26397.1 - 0.12 13.0 0.7 1.8 9.2 0.1 3.1 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3929 PF13066.6 PVD26397.1 - 0.25 11.4 1.3 0.59 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3929) Homeodomain PF00046.29 PVD26398.1 - 3e-16 59.0 0.6 5.2e-16 58.2 0.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD26398.1 - 2.4e-05 24.1 0.5 5.7e-05 22.9 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD26399.1 - 9.1e-15 54.2 3.2 1.8e-14 53.3 3.2 1.5 1 0 0 1 1 1 1 Homeodomain FANC_SAP PF18081.1 PVD26399.1 - 0.093 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain ATG_C PF09333.11 PVD26400.1 - 1.2e-29 102.5 0.1 2.8e-29 101.3 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 PVD26400.1 - 3.2e-07 30.2 0.1 2.1e-05 24.3 0.1 2.7 1 1 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 PVD26400.1 - 0.00032 20.5 0.0 0.00092 19.0 0.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal WD40 PF00400.32 PVD26401.1 - 1.5e-09 38.3 1.7 0.0002 22.1 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26401.1 - 4.9e-07 30.0 0.0 0.0079 16.5 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD26401.1 - 0.034 13.5 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 PVD26401.1 - 0.11 12.4 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Vps54 PF07928.12 PVD26402.1 - 9.7e-47 158.8 0.5 9.7e-47 158.8 0.5 2.8 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 PVD26402.1 - 1.4e-13 50.8 14.8 4.2e-13 49.2 10.8 2.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COMP PF11598.8 PVD26402.1 - 0.4 11.2 2.9 1.1 9.7 0.7 2.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein COG5 PF10392.9 PVD26402.1 - 0.7 10.1 10.2 0.049 13.8 3.8 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 PVD26402.1 - 1.8 8.4 10.9 0.49 10.3 6.5 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain UDPGP PF01704.18 PVD26403.1 - 5e-173 575.5 0.0 2.8e-171 569.7 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF2723 PF11028.8 PVD26404.1 - 8.2e-12 45.4 3.4 2.7e-11 43.7 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Pfg27 PF09216.10 PVD26404.1 - 0.043 13.6 0.9 0.13 12.1 0.4 1.9 2 0 0 2 2 2 0 Pfg27 Ldh_1_C PF02866.18 PVD26406.1 - 6.5e-39 133.5 0.1 1.3e-38 132.6 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PVD26406.1 - 9.9e-35 119.7 0.0 2.3e-34 118.5 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Frtz PF11768.8 PVD26407.1 - 1.6e-163 545.0 0.0 3.9e-140 467.7 0.0 3.0 1 1 2 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz DUF3906 PF13046.6 PVD26407.1 - 0.074 13.2 0.1 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) Mononeg_mRNAcap PF14318.6 PVD26407.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Myb_DNA-bind_5 PF13873.6 PVD26408.1 - 1.2e-13 50.9 0.5 2.5e-13 49.9 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ribosomal_S10 PF00338.22 PVD26408.1 - 2.7e-10 40.4 0.1 6.9e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Myb_DNA-bind_4 PF13837.6 PVD26408.1 - 1.9e-06 28.1 0.2 4.1e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD26408.1 - 0.00015 22.0 0.4 0.00036 20.8 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 PVD26408.1 - 0.0041 17.3 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PVD26408.1 - 0.0043 17.2 0.2 0.022 14.9 0.1 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 PVD26408.1 - 0.051 14.6 0.4 0.14 13.1 0.1 1.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD26409.1 - 4.5e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain B56 PF01603.20 PVD26411.1 - 4.1e-199 661.8 8.1 4.8e-199 661.5 8.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 PVD26413.1 - 8e-81 271.3 0.0 5.1e-36 124.4 0.0 4.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26413.1 - 1.9e-49 168.3 0.0 3.4e-21 75.7 0.0 5.0 4 1 0 4 4 4 4 Protein tyrosine kinase RWD PF05773.22 PVD26413.1 - 2.8e-17 63.1 0.3 2.8e-17 63.1 0.3 2.4 3 0 0 3 3 3 1 RWD domain HGTP_anticodon2 PF12745.7 PVD26413.1 - 2e-14 53.7 4.8 3e-14 53.2 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 PVD26413.1 - 2.4e-11 43.5 0.0 5.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 PVD26413.1 - 2e-06 27.3 0.0 0.058 12.7 0.0 3.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 PVD26413.1 - 0.00042 19.7 1.3 0.03 13.7 0.2 2.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HGTP_anticodon PF03129.20 PVD26413.1 - 0.00065 19.8 0.2 0.0062 16.7 0.1 2.5 2 0 0 2 2 2 1 Anticodon binding domain APH PF01636.23 PVD26413.1 - 0.025 14.5 2.2 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF1154 PF06631.11 PVD26413.1 - 0.51 10.4 5.8 1.6 8.8 5.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Phage_holin_8 PF16931.5 PVD26414.1 - 0.04 13.9 0.3 0.049 13.6 0.3 1.2 1 0 0 1 1 1 0 Putative phage holin Osw5 PF17062.5 PVD26414.1 - 0.12 12.5 1.0 0.16 12.1 1.0 1.4 1 0 0 1 1 1 0 Outer spore wall 5 7tm_1 PF00001.21 PVD26415.1 - 2.7e-18 66.3 0.0 3.1e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UCR_UQCRX_QCR9 PF05365.12 PVD26415.1 - 0.24 11.3 0.3 0.64 10.0 0.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Neur_chan_LBD PF02931.23 PVD26416.1 - 4.1e-35 121.2 0.2 6e-35 120.6 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Cript PF10235.9 PVD26416.1 - 6.8e-23 81.1 0.4 6.8e-23 81.1 0.4 1.8 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT Neur_chan_memb PF02932.16 PVD26416.1 - 0.084 12.9 0.5 0.084 12.9 0.5 2.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region PTS_2-RNA PF01885.16 PVD26417.1 - 1.2e-51 175.3 0.0 1.8e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RCC1 PF00415.18 PVD26418.1 - 9.5e-62 205.4 21.3 7.3e-11 42.5 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD26418.1 - 1.6e-18 66.0 52.1 1.5e-05 24.6 0.3 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.26 PVD26419.1 - 0.00036 20.4 0.2 0.00072 19.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C2H2_jaz PF12171.8 PVD26420.1 - 4e-06 27.0 0.6 1e-05 25.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Polysacc_synt_2 PF02719.15 PVD26420.1 - 0.013 14.7 0.2 0.022 13.9 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-met PF12874.7 PVD26420.1 - 0.023 15.1 0.4 0.023 15.1 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD26420.1 - 0.046 14.0 0.4 0.046 14.0 0.4 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3246 PF11596.8 PVD26420.1 - 3.6 7.0 9.5 0.22 10.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) FBA PF04300.13 PVD26421.1 - 2.1e-47 161.1 0.1 2.8e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.7 PVD26421.1 - 5.9e-13 48.5 3.2 1.1e-12 47.6 3.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD26421.1 - 9.1e-07 28.6 1.7 9.1e-07 28.6 1.7 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 PVD26422.1 - 0.0038 17.5 0.3 0.28 11.5 0.0 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PVD26422.1 - 0.0044 16.6 0.2 0.12 11.9 0.0 3.1 2 1 1 3 3 3 1 PQQ-like domain WD40 PF00400.32 PVD26422.1 - 0.018 15.9 0.1 5.5 8.0 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 PVD26422.1 - 0.051 14.1 0.0 0.96 10.0 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain WD40_like PF17005.5 PVD26422.1 - 0.075 12.3 0.3 8.4 5.6 0.0 2.4 1 1 0 2 2 2 0 WD40-like domain SNAP-25 PF00835.19 PVD26424.1 - 2.6e-22 78.9 0.8 2.6e-22 78.9 0.8 1.7 2 0 0 2 2 1 1 SNAP-25 family DUF5089 PF17002.5 PVD26424.1 - 0.00026 20.9 1.4 0.049 13.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) SNARE PF05739.19 PVD26424.1 - 0.00093 19.1 6.9 0.22 11.6 0.6 2.5 2 0 0 2 2 2 2 SNARE domain DUF16 PF01519.16 PVD26424.1 - 0.0031 18.0 2.3 0.69 10.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 PVD26424.1 - 0.0041 17.5 2.4 0.5 10.8 1.0 2.1 2 0 0 2 2 2 1 Snapin/Pallidin V-SNARE_C PF12352.8 PVD26424.1 - 0.0045 17.2 5.5 0.067 13.5 0.3 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 PVD26424.1 - 0.02 14.9 1.6 3 7.9 0.8 2.2 2 0 0 2 2 2 0 Laminin Domain II DivIC PF04977.15 PVD26424.1 - 0.024 14.4 4.8 0.088 12.6 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator DASH_Dad4 PF08650.10 PVD26424.1 - 0.028 14.4 1.7 2.8 8.0 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad4 Spc7 PF08317.11 PVD26424.1 - 0.036 13.0 2.3 0.58 9.0 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein SOAR PF16533.5 PVD26424.1 - 0.036 14.0 1.1 1.7 8.6 0.0 2.3 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4140 PF13600.6 PVD26424.1 - 0.044 14.2 0.2 11 6.6 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Duo1 PF08651.10 PVD26424.1 - 0.047 13.5 1.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Spectrin PF00435.21 PVD26424.1 - 0.062 13.8 1.2 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Spectrin repeat Phage_GP20 PF06810.11 PVD26424.1 - 0.062 13.1 2.2 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 RasGAP_C PF03836.15 PVD26424.1 - 0.069 13.3 1.9 3.5 7.8 1.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus RmuC PF02646.16 PVD26424.1 - 0.071 12.2 2.7 0.25 10.4 0.7 2.0 2 0 0 2 2 2 0 RmuC family SlyX PF04102.12 PVD26424.1 - 0.095 13.3 5.8 3.4 8.4 0.4 2.2 2 0 0 2 2 2 0 SlyX Rx_N PF18052.1 PVD26424.1 - 0.1 12.9 0.6 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 PVD26424.1 - 0.16 12.0 5.7 2.7 8.0 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 PVD26424.1 - 0.2 12.0 3.1 7.6 7.0 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 PVD26424.1 - 0.22 11.9 7.1 0.87 10.0 0.6 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3552 PF12072.8 PVD26424.1 - 0.25 10.7 4.6 5.2 6.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF948 PF06103.11 PVD26424.1 - 0.29 11.4 1.7 6.9 7.0 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 PVD26424.1 - 0.38 11.1 4.4 4.6 7.6 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 PVD26424.1 - 0.38 11.0 10.3 2.3 8.5 0.3 2.8 3 0 0 3 3 3 0 Haemolysin XhlA DUF4446 PF14584.6 PVD26424.1 - 0.41 10.6 2.8 13 5.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Muted PF14942.6 PVD26424.1 - 0.51 10.7 4.9 0.9 9.9 1.5 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF724 PF05266.14 PVD26424.1 - 0.97 9.2 3.6 2.2 8.1 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CNRIP1 PF15043.6 PVD26425.1 - 0.00021 20.8 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 CAP_GLY PF01302.25 PVD26427.1 - 2.8e-20 72.1 0.2 4.6e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 PVD26427.1 - 8.6e-13 48.3 10.1 6.3e-05 23.3 0.3 3.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD26427.1 - 5e-10 39.2 3.7 3.6e-08 33.1 0.6 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 PVD26427.1 - 3.4e-08 33.1 8.0 0.0093 15.7 0.2 3.8 3 1 0 3 3 3 3 Leucine rich repeat HECT PF00632.25 PVD26428.1 - 1.1e-73 248.5 0.3 1.7e-73 247.8 0.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 PVD26428.1 - 1.1e-10 42.3 0.3 2.6e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Filamin/ABP280 repeat Acyltransferase PF01553.21 PVD26429.1 - 2.3e-20 72.6 0.6 1.3e-19 70.2 0.0 2.4 3 0 0 3 3 3 1 Acyltransferase DUF2240 PF09999.9 PVD26429.1 - 0.013 15.1 0.6 0.14 11.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) UNC-79 PF14776.6 PVD26430.1 - 2.1e-189 630.7 10.8 6.5e-145 483.8 5.3 2.3 1 1 1 2 2 2 2 Cation-channel complex subunit UNC-79 HEAT PF02985.22 PVD26430.1 - 0.047 14.0 0.8 2.1 8.8 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat Thioredoxin PF00085.20 PVD26431.1 - 2.3e-13 50.0 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PVD26431.1 - 6e-05 22.5 0.0 9.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AsnC_trans_reg PF01037.21 PVD26431.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain SCIMP PF15050.6 PVD26431.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein Thioredoxin_3 PF13192.6 PVD26431.1 - 0.023 14.7 0.0 0.08 13.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.6 PVD26431.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin FRG2 PF15315.6 PVD26431.1 - 2.5 8.2 8.4 3.7 7.7 8.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Globin PF00042.22 PVD26432.1 - 7.6e-11 42.5 0.4 1.4e-10 41.7 0.1 1.5 2 0 0 2 2 2 1 Globin Thiamine_BP PF01910.17 PVD26432.1 - 0.14 12.1 0.1 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 Thiamine-binding protein GlgX_C PF18390.1 PVD26434.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Globin PF00042.22 PVD26435.1 - 9.1e-14 52.0 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.22 PVD26437.1 - 1.1e-15 58.1 0.7 1.4e-15 57.8 0.7 1.1 1 0 0 1 1 1 1 Globin DUF4536 PF15055.6 PVD26441.1 - 0.0077 16.4 1.0 0.014 15.6 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) SNF2_N PF00176.23 PVD26442.1 - 2e-29 102.4 0.4 3.6e-29 101.6 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD26442.1 - 2.5e-12 47.1 0.2 3e-11 43.6 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD26442.1 - 2.6e-08 34.1 0.0 2.4e-07 30.9 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit HNH PF01844.23 PVD26442.1 - 2.7e-08 33.8 7.3 1.5e-07 31.4 0.1 4.0 4 0 0 4 4 4 1 HNH endonuclease zf-RanBP PF00641.18 PVD26442.1 - 3.4e-06 26.2 2.4 3.4e-06 26.2 2.4 2.4 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others HNH_5 PF14279.6 PVD26442.1 - 0.024 14.5 3.1 0.11 12.4 0.1 2.9 2 0 0 2 2 2 0 HNH endonuclease DUF4412 PF14371.6 PVD26442.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) PAP2 PF01569.21 PVD26443.1 - 1.4e-15 57.3 2.7 5e-15 55.5 2.7 2.0 1 0 0 1 1 1 1 PAP2 superfamily Steroid_dh PF02544.16 PVD26443.1 - 0.36 10.8 4.6 0.28 11.2 0.8 2.6 3 1 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Lipase_2 PF01674.18 PVD26445.1 - 0.0017 17.9 0.9 0.64 9.5 0.1 2.6 2 2 0 2 2 2 2 Lipase (class 2) RuBisCO_large PF00016.20 PVD26445.1 - 0.024 13.8 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Imm2 PF14426.6 PVD26445.1 - 0.051 13.6 0.2 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Immunity protein Imm2 VEGFR-2_TMD PF17988.1 PVD26445.1 - 0.057 12.9 0.1 13 5.3 0.0 2.3 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain GnHR_trans PF12369.8 PVD26445.1 - 0.067 14.0 0.5 27 5.6 0.0 2.9 2 1 1 3 3 3 0 Gonadotropin hormone receptor transmembrane region TonB_C PF03544.14 PVD26446.1 - 0.046 14.2 0.2 6.1 7.4 0.0 2.4 1 1 1 2 2 2 0 Gram-negative bacterial TonB protein C-terminal Tyr_Deacylase PF02580.16 PVD26447.1 - 8.5e-52 175.5 0.0 1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TonB_2 PF13103.6 PVD26447.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TonB C terminal Hva1_TUDOR PF11160.8 PVD26449.1 - 0.42 10.8 2.1 0.68 10.1 0.9 1.9 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain ELM2 PF01448.24 PVD26451.1 - 2.9e-07 31.1 0.0 9e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain zf-C2H2_4 PF13894.6 PVD26451.1 - 6e-07 29.8 7.0 0.0076 17.0 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD26451.1 - 2.4e-06 27.7 7.5 0.004 17.5 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PVD26451.1 - 1.2e-05 25.1 8.9 0.011 15.7 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 PVD26451.1 - 0.00017 21.9 2.1 0.0084 16.5 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Myb_DNA-binding PF00249.31 PVD26451.1 - 0.00022 21.3 0.1 0.00036 20.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.8 PVD26451.1 - 0.0017 18.6 1.4 0.0058 16.9 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD26451.1 - 0.017 15.5 7.4 0.31 11.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain SMN PF06003.12 PVD26451.1 - 0.13 11.5 6.5 0.35 10.1 6.5 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Myb_DNA-bind_7 PF15963.5 PVD26451.1 - 0.15 12.0 0.4 0.32 10.9 0.4 1.5 1 0 0 1 1 1 0 Myb DNA-binding like zf-C2H2_2 PF12756.7 PVD26451.1 - 0.67 10.3 2.2 4.3 7.7 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PVD26452.1 - 3.2e-15 55.6 24.2 0.00046 20.5 2.0 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD26452.1 - 7.6e-14 51.2 18.1 0.0075 17.0 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD26452.1 - 1.8e-13 50.1 10.4 0.00024 21.0 1.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 PVD26452.1 - 1.7e-07 31.4 7.2 0.22 12.0 0.2 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD26452.1 - 6.8e-06 26.2 12.4 0.08 13.2 0.2 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 PVD26452.1 - 0.00083 19.2 0.1 0.00083 19.2 0.1 3.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 PVD26452.1 - 0.0022 18.4 32.7 0.0077 16.6 0.9 5.9 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_9 PF16293.5 PVD26452.1 - 0.0055 16.5 1.7 0.43 10.5 0.0 3.2 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 PVD26452.1 - 0.13 12.6 14.7 0.028 14.7 4.0 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD26452.1 - 0.27 11.0 13.6 4 7.3 0.6 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type PCI PF01399.27 PVD26452.1 - 1.6 9.3 5.3 2.1 8.9 3.3 2.2 2 1 0 2 2 2 0 PCI domain GBP PF02263.19 PVD26453.1 - 3.9e-95 318.0 0.0 5.2e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 PVD26453.1 - 0.00035 20.1 1.1 0.00056 19.4 1.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 PVD26453.1 - 0.008 16.6 0.2 0.024 15.0 0.0 1.9 2 0 0 2 2 2 1 T-lymphoma invasion and metastasis CC-Ex domain DUF2207 PF09972.9 PVD26453.1 - 0.03 13.1 0.1 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TcpE PF12648.7 PVD26453.1 - 0.13 12.8 1.3 0.35 11.4 1.3 1.6 1 0 0 1 1 1 0 TcpE family DUF2149 PF09919.9 PVD26453.1 - 0.67 10.2 3.3 26 5.1 1.6 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) LRR_6 PF13516.6 PVD26454.1 - 1.9e-19 68.0 24.0 0.002 18.1 0.3 8.8 9 0 0 9 9 8 6 Leucine Rich repeat EF-hand_7 PF13499.6 PVD26454.1 - 4.5e-09 36.6 8.4 7.9e-08 32.6 2.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD26454.1 - 2e-08 33.2 4.4 0.00037 19.8 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD26454.1 - 8.9e-08 31.5 2.8 0.0012 18.6 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD26454.1 - 6e-06 25.5 6.5 0.0025 17.2 0.9 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD26454.1 - 9.4e-06 25.4 2.5 0.012 15.5 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair LRR_1 PF00560.33 PVD26454.1 - 4.1e-05 23.5 6.4 1.2 9.9 0.1 6.6 5 3 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 PVD26454.1 - 0.00043 20.6 7.6 0.72 10.4 0.2 5.0 5 1 0 5 5 4 1 Leucine Rich repeats (2 copies) EF-hand_11 PF08976.11 PVD26454.1 - 0.014 16.2 0.0 0.031 15.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain LRR_8 PF13855.6 PVD26454.1 - 0.085 12.6 11.7 2.5 7.9 1.4 5.3 4 2 1 5 5 5 0 Leucine rich repeat DCD PF06559.11 PVD26454.1 - 0.089 11.6 0.0 5.6 5.6 0.0 2.3 2 0 0 2 2 2 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Fib_succ_major PF09603.10 PVD26454.1 - 0.14 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) DUF4106 PF13388.6 PVD26456.1 - 0.09 12.0 13.3 0.15 11.3 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TraT PF05818.12 PVD26458.1 - 0.048 13.3 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein RT_RNaseH_2 PF17919.1 PVD26459.1 - 7.9e-34 115.7 0.0 1.7e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD26459.1 - 8.6e-34 116.0 0.0 1.8e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD26459.1 - 2.5e-21 76.2 0.1 3.9e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PVD26459.1 - 5.8e-21 74.9 0.0 3.6e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 PVD26459.1 - 6.9e-20 70.9 0.6 1.6e-19 69.7 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 PVD26459.1 - 0.00024 21.0 2.6 0.00024 21.0 2.6 2.1 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 PVD26459.1 - 0.0012 18.6 0.0 0.0036 17.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain LolA_2 PF16584.5 PVD26459.1 - 0.0039 17.1 0.1 0.013 15.4 0.3 1.7 2 0 0 2 2 2 1 Outer membrane lipoprotein carrier protein LolA MLVIN_C PF18697.1 PVD26459.1 - 0.012 15.7 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain LCIB_C_CA PF18599.1 PVD26460.1 - 0.091 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases NUDE_C PF04880.13 PVD26466.1 - 0.088 13.3 3.6 0.093 13.2 3.6 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region bZIP_1 PF00170.21 PVD26467.1 - 3.7e-11 42.9 13.7 3.7e-11 42.9 13.7 1.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PVD26467.1 - 6e-08 32.7 15.9 6e-08 32.7 15.9 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD26467.1 - 0.00012 22.6 13.5 0.00017 22.0 13.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Sod_Ni PF09055.11 PVD26467.1 - 0.055 14.0 2.8 0.52 10.9 0.9 2.0 1 1 1 2 2 2 0 Nickel-containing superoxide dismutase RapA_C PF12137.8 PVD26467.1 - 0.067 12.2 7.4 0.078 12.0 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PI-PLC-Y PF00387.19 PVD26467.1 - 0.12 12.7 2.3 0.16 12.3 2.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain HIP1_clath_bdg PF16515.5 PVD26467.1 - 0.16 12.6 10.5 0.2 12.3 10.5 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BCAS2 PF05700.11 PVD26467.1 - 0.18 11.5 9.7 0.2 11.3 9.7 1.0 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) UPF0449 PF15136.6 PVD26467.1 - 0.21 12.1 5.4 0.3 11.6 5.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Prominin PF05478.11 PVD26467.1 - 0.27 9.1 4.5 0.29 9.0 4.5 1.0 1 0 0 1 1 1 0 Prominin Bac_export_2 PF01312.19 PVD26467.1 - 0.74 9.0 5.6 0.82 8.8 5.6 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family CENP-H PF05837.12 PVD26467.1 - 4.7 7.7 14.3 2.8 8.4 3.9 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 PVD26469.1 - 4.8e-07 29.8 15.2 9.1e-07 28.9 15.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD26469.1 - 7.3e-07 29.2 13.2 1.4e-06 28.3 13.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD26469.1 - 0.79 10.3 12.3 1.6 9.3 12.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SR-25 PF10500.9 PVD26469.1 - 2.2 7.8 14.4 1.3 8.5 3.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rrp44_CSD1 PF17216.3 PVD26470.1 - 0.17 11.6 2.7 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Rrp44-like cold shock domain bZIP_1 PF00170.21 PVD26473.1 - 2.6e-07 30.6 11.0 4.6e-07 29.9 11.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD26473.1 - 2.5e-06 27.9 14.9 7e-06 26.5 14.9 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.9 PVD26473.1 - 0.0022 16.6 6.8 0.003 16.2 6.8 1.1 1 0 0 1 1 1 1 Macoilin family bZIP_2 PF07716.15 PVD26473.1 - 0.03 14.4 19.2 0.24 11.5 19.2 2.3 1 1 0 1 1 1 0 Basic region leucine zipper Nsp1_C PF05064.13 PVD26473.1 - 0.39 10.5 3.1 0.82 9.5 3.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region M PF02370.16 PVD26473.1 - 2.4 9.0 8.5 0.64 10.8 1.2 2.6 1 1 1 2 2 2 0 M protein repeat EF-hand_1 PF00036.32 PVD26474.1 - 1.2e-28 96.5 11.4 3e-09 35.8 0.7 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD26474.1 - 8.4e-25 84.5 6.6 4.3e-09 35.6 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PVD26474.1 - 6.3e-23 81.0 3.5 1.8e-15 57.1 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD26474.1 - 5.6e-20 69.9 10.7 7.9e-08 31.5 0.8 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PVD26474.1 - 3.4e-12 46.0 9.8 9.3e-09 35.0 1.0 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 PVD26474.1 - 8.6e-08 32.4 0.2 5.3e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD26474.1 - 7e-05 23.1 0.2 0.13 12.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD26474.1 - 0.015 15.3 0.2 0.089 12.7 0.0 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 PVD26474.1 - 0.018 15.0 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 PVD26474.1 - 0.018 15.2 2.3 3.8 7.8 0.6 2.7 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 PVD26474.1 - 0.024 14.6 0.6 5.1 7.0 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein LXG PF04740.12 PVD26474.1 - 0.091 12.5 0.2 0.17 11.6 0.2 1.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily EF-hand_1 PF00036.32 PVD26476.1 - 3.3e-37 123.3 9.9 1.5e-09 36.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD26476.1 - 3.2e-32 110.8 1.5 4.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD26476.1 - 6.8e-29 99.5 9.3 6.2e-13 48.4 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD26476.1 - 2.2e-26 89.5 5.7 2.5e-09 36.3 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD26476.1 - 7.3e-24 82.2 7.3 1.4e-06 27.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PVD26476.1 - 5.4e-13 49.1 0.1 5.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PVD26476.1 - 5.8e-07 29.4 0.2 0.028 14.4 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PVD26476.1 - 1.2e-05 25.6 0.0 0.076 13.3 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PVD26476.1 - 7.3e-05 22.7 0.0 0.082 12.9 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 PVD26476.1 - 0.00041 20.4 0.2 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 PVD26476.1 - 0.00047 21.0 0.0 0.12 13.3 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 PVD26476.1 - 0.00097 18.8 2.9 0.0012 18.5 2.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Dockerin_1 PF00404.18 PVD26476.1 - 0.0033 17.6 4.8 0.22 11.7 0.5 3.0 1 1 2 3 3 3 1 Dockerin type I domain DUF3349 PF11829.8 PVD26476.1 - 0.0066 17.2 0.4 2.8 8.8 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 PVD26476.1 - 0.009 16.0 0.2 1.1 9.2 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 PVD26476.1 - 0.0096 16.2 0.5 3 8.2 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 PVD26476.1 - 0.01 16.3 0.0 3.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 PVD26476.1 - 0.018 15.2 2.5 2 8.6 2.5 2.9 1 1 0 1 1 1 0 RloB-like protein MotA_activ PF09114.10 PVD26476.1 - 0.025 14.7 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 PVD26476.1 - 0.03 13.5 0.1 1.2 8.3 0.0 2.2 1 1 0 2 2 2 0 Cache domain Poly_export PF02563.16 PVD26476.1 - 0.063 13.5 0.0 2 8.7 0.0 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 PVD26476.1 - 0.17 11.7 0.4 8.4 6.3 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain SHIPPO-rpt PF07004.12 PVD26477.1 - 4.8 8.3 17.6 8.6 7.5 0.4 5.3 5 2 0 5 5 5 0 Sperm-tail PG-rich repeat MTA_R1 PF17226.2 PVD26478.1 - 1.9e-31 108.0 4.7 4.6e-30 103.6 2.2 2.8 2 0 0 2 2 2 1 MTA R1 domain BAH PF01426.18 PVD26478.1 - 1.9e-31 108.4 0.3 1.8e-20 73.0 0.1 2.5 2 0 0 2 2 2 2 BAH domain ELM2 PF01448.24 PVD26478.1 - 9.2e-14 51.9 0.0 2.9e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 PVD26478.1 - 1.4e-07 31.0 7.6 1.4e-07 31.0 7.6 2.0 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-binding PF00249.31 PVD26478.1 - 5.2e-06 26.5 0.1 1.2e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 PVD26478.1 - 0.0048 17.3 3.1 0.0088 16.5 0.7 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Myb_DNA-bind_7 PF15963.5 PVD26478.1 - 0.01 15.7 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 Myb DNA-binding like ROS_MUCR PF05443.11 PVD26478.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Cpn60_TCP1 PF00118.24 PVD26479.1 - 1.7e-155 518.4 11.7 2.1e-155 518.1 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps52 PF04129.12 PVD26479.1 - 0.02 13.6 0.1 0.82 8.3 0.5 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family Peroxidase_ext PF11895.8 PVD26479.1 - 0.05 13.6 0.3 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Fungal peroxidase extension region WD40 PF00400.32 PVD26480.1 - 3.4e-21 75.1 14.3 3.5e-05 24.5 0.2 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26480.1 - 0.083 13.2 0.2 3.5 8.0 0.0 3.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Arginase PF00491.21 PVD26481.1 - 5.1e-40 137.7 0.2 3.9e-22 79.1 0.1 2.0 1 1 1 2 2 2 2 Arginase family SBP_bac_3 PF00497.20 PVD26482.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 PVD26482.1 - 1.6e-05 25.0 0.0 0.16 12.1 0.0 2.3 1 1 1 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD26482.1 - 0.041 13.0 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Lig_chan PF00060.26 PVD26483.1 - 4.8e-10 39.5 0.0 5.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel eIF-1a PF01176.19 PVD26486.1 - 1.6e-19 69.5 0.5 2.4e-19 68.9 0.5 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CDC45 PF02724.14 PVD26486.1 - 1.1 7.4 7.6 1.4 7.2 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BAF PF02961.14 PVD26487.1 - 1.3e-51 173.0 0.1 1.7e-41 140.6 0.3 2.0 1 1 1 2 2 2 2 Barrier to autointegration factor IMS_HHH PF11798.8 PVD26487.1 - 5.2e-05 23.3 0.0 0.5 10.8 0.0 2.5 2 0 0 2 2 2 2 IMS family HHH motif NOG1 PF06858.14 PVD26487.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) PH PF00169.29 PVD26488.1 - 1.8e-12 47.7 0.1 5.2e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD26488.1 - 1.6 9.2 8.2 0.43 11.0 2.2 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain DUF1664 PF07889.12 PVD26488.1 - 1.8 8.6 30.8 0.21 11.6 10.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Vip3A_N PF12495.8 PVD26488.1 - 2.6 7.9 8.4 15 5.4 0.3 2.5 1 1 0 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF948 PF06103.11 PVD26488.1 - 4.3 7.7 18.5 0.29 11.4 2.5 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ER_lumen_recept PF00810.18 PVD26490.1 - 0.1 13.4 3.3 0.23 12.3 3.3 1.5 1 1 0 1 1 1 0 ER lumen protein retaining receptor MARVEL PF01284.23 PVD26493.1 - 0.00052 20.1 17.0 0.0013 18.8 17.0 1.7 1 1 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.23 PVD26495.1 - 0.06 13.4 6.4 0.1 12.6 6.4 1.3 1 1 0 1 1 1 0 Membrane-associating domain Myco_arth_vir_N PF09610.10 PVD26496.1 - 0.46 10.6 8.5 0.14 12.2 1.1 2.8 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Lyase_1 PF00206.20 PVD26497.1 - 1.7e-114 382.4 0.0 2.2e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PVD26497.1 - 1.7e-24 86.0 0.1 4.4e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus FTHFS PF01268.19 PVD26498.1 - 2e-240 798.8 0.1 3.4e-240 798.0 0.1 1.4 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 PVD26498.1 - 7.1e-134 441.5 8.5 3.3e-67 224.8 0.6 2.9 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PVD26498.1 - 2.3e-65 218.1 6.6 1.6e-33 115.4 0.8 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BChl_A PF02327.17 PVD26498.1 - 0.018 13.8 0.2 7 5.3 0.0 3.0 3 0 0 3 3 3 0 Bacteriochlorophyll A protein RuvX PF03652.15 PVD26498.1 - 0.07 13.5 0.8 14 6.1 0.1 2.9 3 0 0 3 3 3 0 Holliday junction resolvase CbiA PF01656.23 PVD26498.1 - 0.14 12.2 0.0 0.63 10.1 0.0 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Redoxin PF08534.10 PVD26499.1 - 2.4e-28 98.7 0.0 3e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PVD26499.1 - 2.5e-13 50.1 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 PVD26499.1 - 0.047 13.8 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme RGS PF00615.19 PVD26500.1 - 4.1e-31 107.7 18.0 2.5e-08 34.2 3.3 5.0 4 1 0 4 4 4 4 Regulator of G protein signaling domain DUF2379 PF09543.10 PVD26500.1 - 0.018 15.3 0.4 0.24 11.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) Ion_trans_2 PF07885.16 PVD26501.1 - 2.4e-31 107.5 13.6 4e-16 58.7 1.2 2.5 2 1 0 2 2 2 2 Ion channel AbrB PF05145.12 PVD26501.1 - 0.0025 16.8 1.9 0.003 16.6 0.7 1.7 1 1 0 1 1 1 1 Transition state regulatory protein AbrB Ion_trans PF00520.31 PVD26501.1 - 0.014 14.7 10.0 0.025 13.8 0.5 2.4 1 1 1 2 2 2 0 Ion transport protein DUF2555 PF10742.9 PVD26501.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) DUF4112 PF13430.6 PVD26501.1 - 0.25 11.7 3.8 0.5 10.7 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Lig_chan PF00060.26 PVD26501.1 - 0.31 10.9 1.2 3 7.7 0.1 2.6 1 1 1 2 2 2 0 Ligand-gated ion channel Lung_7-TM_R PF06814.13 PVD26501.1 - 0.88 8.8 7.1 1.7 7.8 0.1 2.8 3 0 0 3 3 3 0 Lung seven transmembrane receptor DUF4203 PF13886.6 PVD26501.1 - 1.1 8.8 13.0 1.6 8.3 10.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) MpPF26 PF07666.11 PVD26501.1 - 2.1 8.5 11.7 3.2 7.9 1.0 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 DSPc PF00782.20 PVD26502.1 - 2.5e-16 59.7 0.0 3.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD26502.1 - 0.0049 16.5 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PVD26502.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Kinesin PF00225.23 PVD26503.1 - 2.1e-79 266.9 0.0 2.1e-79 266.9 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD26503.1 - 9.2e-26 90.6 0.2 6.1e-25 87.9 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding PX PF00787.24 PVD26503.1 - 5.3e-16 58.6 2.3 9.7e-16 57.8 0.1 2.6 2 0 0 2 2 2 1 PX domain FHA PF00498.26 PVD26503.1 - 1.3e-06 28.6 0.3 6.8e-05 23.1 0.0 3.3 3 0 0 3 3 3 1 FHA domain Kinesin_assoc PF16183.5 PVD26503.1 - 2.8e-05 24.4 1.8 0.0047 17.1 0.2 5.9 2 2 2 4 4 4 2 Kinesin-associated Yop-YscD_cpl PF16697.5 PVD26503.1 - 6.5e-05 23.2 0.1 0.00066 20.0 0.0 2.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Elf4 PF07011.11 PVD26503.1 - 0.87 9.5 6.3 4.3 7.3 0.2 3.5 3 0 0 3 3 3 0 Early Flowering 4 domain DSPc PF00782.20 PVD26504.1 - 1.9e-29 102.1 0.0 2.5e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SIS_2 PF13580.6 PVD26504.1 - 0.0003 20.8 0.1 0.00082 19.4 0.1 1.6 1 1 0 2 2 2 1 SIS domain Init_tRNA_PT PF04179.12 PVD26504.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain UPF0669 PF17065.5 PVD26505.1 - 1.2e-24 87.1 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 TBP PF00352.21 PVD26506.1 - 4e-67 222.2 0.4 2.6e-33 113.8 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PVD26506.1 - 2e-05 24.6 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) BACK PF07707.15 PVD26508.1 - 3.6e-33 113.7 0.5 7.7e-33 112.7 0.5 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 PVD26508.1 - 3.9e-31 106.3 3.1 1.9e-08 34.3 0.0 7.0 5 2 2 7 7 7 4 Kelch motif Kelch_1 PF01344.25 PVD26508.1 - 7.5e-27 92.7 3.6 8.3e-10 38.1 0.0 6.3 7 0 0 7 7 7 3 Kelch motif BTB PF00651.31 PVD26508.1 - 2.4e-26 92.1 0.6 4.8e-26 91.2 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 PVD26508.1 - 6.7e-17 61.2 1.8 9.7e-05 22.3 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD26508.1 - 1e-16 60.2 4.6 3.8e-05 23.5 0.0 6.0 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PVD26508.1 - 1.8e-09 37.4 3.3 0.00087 19.2 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 PVD26508.1 - 3.9e-08 33.4 0.2 0.0038 17.5 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF3342 PF11822.8 PVD26508.1 - 0.0016 18.6 0.1 0.0065 16.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) hEGF PF12661.7 PVD26510.1 - 0.017 15.7 0.2 0.017 15.7 0.2 2.5 2 1 0 2 2 2 0 Human growth factor-like EGF IPP-2 PF04979.14 PVD26510.1 - 0.53 11.0 2.3 0.39 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) GMC_oxred_N PF00732.19 PVD26511.1 - 3.7e-44 151.3 0.0 5.4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PVD26511.1 - 6.7e-43 146.6 0.0 1e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Tat PF00539.18 PVD26511.1 - 0.084 13.0 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) GMC_oxred_C PF05199.13 PVD26512.1 - 1.5e-45 155.3 0.0 2.2e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 PVD26512.1 - 3.6e-44 151.3 0.0 5.4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Tat PF00539.18 PVD26512.1 - 0.082 13.1 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) LURAP PF14854.6 PVD26513.1 - 1.4e-11 44.4 0.1 5e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Leucine rich adaptor protein EGF PF00008.27 PVD26514.1 - 5.5e-09 36.2 23.8 7.1e-09 35.8 9.8 8.4 8 0 0 8 8 8 5 EGF-like domain hEGF PF12661.7 PVD26514.1 - 1.3e-05 25.6 7.4 1.3e-05 25.6 7.4 10.3 11 0 0 11 11 11 2 Human growth factor-like EGF EGF_CA PF07645.15 PVD26514.1 - 0.0062 16.7 11.9 0.0062 16.7 11.9 6.5 6 1 1 7 7 7 2 Calcium-binding EGF domain VCX_VCY PF15231.6 PVD26515.1 - 1.2e-08 35.7 20.5 1.2 9.8 0.8 6.1 1 1 5 7 7 7 7 Variable charge X/Y family DUF240 PF03086.14 PVD26515.1 - 4.9e-06 26.4 12.0 0.13 12.2 0.4 5.8 1 1 4 5 5 5 3 Domain of unknown function (DUF240) DUF5553 PF17707.1 PVD26515.1 - 0.25 10.8 12.0 17 4.8 0.3 5.3 1 1 6 7 7 7 0 Family of unknown function (DUF5553) Flavi_DEAD PF07652.14 PVD26515.1 - 0.29 11.1 2.9 4 7.4 0.3 3.3 1 1 2 4 4 4 0 Flavivirus DEAD domain EGF PF00008.27 PVD26516.1 - 2.9e-16 59.4 64.6 2.7e-05 24.3 8.3 9.2 8 0 0 8 8 8 6 EGF-like domain MTH865 PF07747.11 PVD26516.1 - 1.7e-05 24.5 0.4 2.6 7.9 0.0 4.1 4 0 0 4 4 4 3 MTH865-like family hEGF PF12661.7 PVD26516.1 - 3.5e-05 24.3 57.0 0.0052 17.4 6.5 9.1 7 0 0 7 7 7 3 Human growth factor-like EGF UPF0669 PF17065.5 PVD26516.1 - 0.027 14.2 0.8 53 3.5 0.0 4.4 5 0 0 5 5 5 0 Putative cytokine, C6ORF120 DAN PF03045.15 PVD26517.1 - 1.2e-29 102.7 9.6 1.5e-29 102.3 9.6 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 PVD26517.1 - 0.0045 17.3 8.0 0.0065 16.7 8.0 1.2 1 0 0 1 1 1 1 Cystine-knot domain Spy1 PF11357.8 PVD26519.1 - 6.8e-41 139.6 1.7 8.5e-41 139.3 1.7 1.1 1 0 0 1 1 1 1 Cell cycle regulatory protein DUF1230 PF06799.11 PVD26519.1 - 0.18 11.9 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 ABC_membrane PF00664.23 PVD26520.1 - 1.6e-33 116.5 9.1 1.6e-33 116.5 9.1 2.8 3 1 1 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD26520.1 - 2.2e-31 109.2 0.6 1e-21 77.9 0.0 3.4 3 1 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 PVD26520.1 - 1.3e-07 31.7 0.1 0.0064 16.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 PVD26520.1 - 2.8e-07 30.2 5.7 0.69 9.3 0.4 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD26520.1 - 2.6e-06 27.5 2.5 0.28 11.0 1.2 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD26520.1 - 2.8e-05 23.8 2.7 0.042 13.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD26520.1 - 4.7e-05 23.8 0.1 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PVD26520.1 - 0.00025 21.0 2.4 0.007 16.3 0.4 2.4 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 PVD26520.1 - 0.00026 20.3 0.0 0.051 12.8 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain MeaB PF03308.16 PVD26520.1 - 0.00028 20.0 0.6 0.49 9.3 0.2 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PVD26520.1 - 0.00076 19.8 0.5 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 PVD26520.1 - 0.00083 19.0 0.0 0.46 10.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 PVD26520.1 - 0.0013 19.2 0.8 0.76 10.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PVD26520.1 - 0.0016 18.6 4.5 0.75 9.8 1.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 PVD26520.1 - 0.0038 17.3 2.2 0.036 14.1 0.2 2.6 2 0 0 2 2 2 1 Dynamin family ATP-synt_ab PF00006.25 PVD26520.1 - 0.0092 15.7 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 PVD26520.1 - 0.014 15.1 0.1 1.1 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PVD26520.1 - 0.04 12.8 0.5 1.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 PVD26520.1 - 0.048 13.2 0.4 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 PVD26520.1 - 0.051 12.6 0.0 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 PVD26520.1 - 0.053 13.2 0.3 1.8 8.2 0.1 3.0 4 0 0 4 4 4 0 AAA ATPase domain Roc PF08477.13 PVD26520.1 - 0.056 13.7 0.2 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 PVD26520.1 - 0.068 12.5 2.0 6.2 6.1 0.5 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 PVD26520.1 - 0.093 12.0 0.2 0.6 9.4 0.2 2.0 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 PVD26520.1 - 0.11 11.9 1.4 10 5.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 PVD26520.1 - 0.13 12.2 0.2 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.13 PVD26520.1 - 0.15 11.2 0.2 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 PVD26520.1 - 0.17 11.4 0.0 0.67 9.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 PVD26520.1 - 0.72 9.0 4.5 11 5.1 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain NACHT PF05729.12 PVD26520.1 - 0.76 9.7 2.1 7.2 6.5 0.1 2.6 2 1 0 2 2 2 0 NACHT domain Bap31_Bap29_C PF18035.1 PVD26523.1 - 0.038 14.0 0.3 0.075 13.0 0.3 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4193 PF13834.6 PVD26523.1 - 0.99 9.9 6.2 0.24 11.9 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4193) FXMR_C2 PF16098.5 PVD26523.1 - 1.7 9.2 5.6 0.29 11.7 0.9 2.1 3 0 0 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 Tyr_Deacylase PF02580.16 PVD26525.1 - 4.9e-31 108.2 0.0 6.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GpcrRhopsn4 PF10192.9 PVD26526.1 - 4.7e-52 176.9 25.2 5.9e-52 176.6 25.2 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Astacin PF01400.24 PVD26527.1 - 2.5e-59 200.1 0.1 3.9e-59 199.5 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 PVD26527.1 - 5.5e-22 78.2 0.0 1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 CUB domain Reprolysin_4 PF13583.6 PVD26527.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD26527.1 - 0.13 12.3 0.7 0.26 11.4 0.7 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD26527.1 - 0.22 12.1 4.1 0.42 11.1 1.6 2.6 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD26527.1 - 0.74 9.7 5.8 0.4 10.5 0.9 2.3 2 1 0 3 3 3 0 Matrixin TUDOR PF00567.24 PVD26528.1 - 1.4e-17 63.8 0.1 6.4e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Tudor domain Helicase_C PF00271.31 PVD26528.1 - 5.5e-14 52.5 0.0 1.7e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD26528.1 - 3e-12 46.6 0.7 6.5e-12 45.6 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 PVD26528.1 - 4.5e-11 43.0 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 PVD26528.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD26528.1 - 0.0021 18.4 0.1 0.0042 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PVD26528.1 - 0.0024 17.9 0.2 0.023 14.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 PVD26528.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein FtsK_SpoIIIE PF01580.18 PVD26528.1 - 0.02 14.2 0.0 0.79 9.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 PVD26528.1 - 0.032 14.2 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 PVD26528.1 - 0.047 13.6 0.0 0.32 10.9 0.0 2.3 2 1 0 2 2 2 0 NACHT domain ATPase PF06745.13 PVD26528.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 PVD26528.1 - 0.13 12.5 2.1 0.48 10.7 0.3 2.7 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 PVD26528.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Helicase zf-C2H2 PF00096.26 PVD26528.1 - 1.9 9.1 4.3 0.66 10.5 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA_23 PF13476.6 PVD26528.1 - 2.1 8.8 3.9 1.5 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain cwf21 PF08312.12 PVD26529.1 - 0.011 15.8 0.0 0.039 14.1 0.0 2.3 1 1 0 1 1 1 0 cwf21 domain Myc_N PF01056.18 PVD26529.1 - 0.076 12.9 0.6 0.1 12.5 0.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.6 PVD26529.1 - 0.21 11.8 2.8 0.39 11.0 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Rrp15p PF07890.12 PVD26532.1 - 0.001 19.4 0.4 0.001 19.4 0.4 1.5 2 0 0 2 2 2 1 Rrp15p Big_3_3 PF13750.6 PVD26532.1 - 0.032 13.9 0.2 0.035 13.7 0.2 1.0 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Gastrin PF00918.17 PVD26532.1 - 0.043 14.8 1.5 1.7 9.7 0.2 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Goodbye PF17109.5 PVD26532.1 - 0.045 14.2 2.8 1.8 9.0 0.3 2.0 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain GCIP PF13324.6 PVD26532.1 - 0.16 11.6 4.0 0.18 11.4 4.0 1.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cu_bind_like PF02298.17 PVD26533.1 - 0.00018 21.5 0.2 0.0005 20.0 0.2 1.7 1 0 0 1 1 1 1 Plastocyanin-like domain IL17R_fnIII_D1 PF16556.5 PVD26533.1 - 0.013 15.2 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 CHRD PF07452.12 PVD26533.1 - 0.073 14.0 0.8 33 5.5 0.0 3.6 4 1 0 4 4 4 0 CHRD domain 7tm_1 PF00001.21 PVD26535.1 - 2.4e-31 109.0 14.2 3.3e-31 108.6 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 PVD26535.1 - 2.3e-09 36.9 10.2 3.7e-06 26.6 0.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 PVD26535.1 - 4.3e-07 29.9 1.2 8.1e-07 29.1 1.2 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD26535.1 - 2.4 8.7 4.5 5.7 7.5 0.9 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) TFIIA PF03153.13 PVD26536.1 - 2.8e-75 254.9 34.9 1.5e-48 166.9 19.5 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 PVD26536.1 - 0.093 11.0 4.1 0.12 10.7 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 PVD26536.1 - 0.96 7.5 13.4 1.4 6.9 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 PVD26536.1 - 1 7.5 11.3 1.4 7.1 11.3 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 PVD26536.1 - 2.9 7.2 12.9 3.9 6.7 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 PVD26536.1 - 7.7 5.8 12.4 11 5.4 12.4 1.2 1 0 0 1 1 1 0 SDA1 PBSX_XtrA PF17356.2 PVD26537.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Kunitz_BPTI PF00014.23 PVD26538.1 - 4.7e-58 193.2 36.0 1.1e-19 70.4 2.8 4.0 4 0 0 4 4 4 3 Kunitz/Bovine pancreatic trypsin inhibitor domain WW PF00397.26 PVD26538.1 - 0.031 14.3 1.7 7.3 6.8 0.2 3.2 3 0 0 3 3 3 0 WW domain Abhydrolase_3 PF07859.13 PVD26539.1 - 6.6e-50 169.9 0.0 8.8e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD26539.1 - 2.3e-05 23.5 0.6 0.0001 21.4 0.7 1.8 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 PVD26539.1 - 0.00035 20.2 0.8 0.0036 16.9 0.8 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PVD26540.1 - 1.3e-42 146.1 0.1 2e-23 83.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 PVD26540.1 - 0.0064 15.4 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family PP2C PF00481.21 PVD26541.1 - 2.7e-68 230.4 0.0 1.2e-61 208.6 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_C PF07830.13 PVD26541.1 - 2.6e-27 95.1 0.2 4.1e-27 94.4 0.2 1.3 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Pecanex_C PF05041.15 PVD26542.1 - 1.4e-116 387.9 0.0 2.4e-116 387.1 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Pkinase_Tyr PF07714.17 PVD26543.1 - 1.9e-64 217.5 0.0 2.7e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD26543.1 - 3.9e-58 196.9 0.0 8e-58 195.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain SH3_1 PF00018.28 PVD26543.1 - 2.5e-12 46.2 0.0 5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD26543.1 - 4.8e-12 45.5 0.0 1.4e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD26543.1 - 1.7e-10 40.4 0.0 3.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_fungal PF17667.1 PVD26543.1 - 0.0044 15.9 0.7 0.0087 14.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD26543.1 - 0.15 11.9 1.2 1.2 9.0 0.0 2.5 1 1 2 3 3 3 0 Phosphotransferase enzyme family DUF3552 PF12072.8 PVD26543.1 - 0.17 11.3 10.6 0.29 10.5 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 PVD26543.1 - 0.87 9.9 7.6 1.6 9.0 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vac7 PF12751.7 PVD26543.1 - 2 7.8 10.0 0.7 9.3 5.9 2.2 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Anoctamin PF04547.12 PVD26544.1 - 0.31 9.8 0.5 0.43 9.4 0.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel G-patch PF01585.23 PVD26545.1 - 9.5e-15 54.2 0.7 2.1e-14 53.1 0.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD26545.1 - 2.6e-06 27.4 0.1 1.1e-05 25.4 0.1 2.1 1 0 0 1 1 1 1 G-patch domain Herpes_BLRF2 PF05812.12 PVD26545.1 - 0.0089 16.2 0.1 0.13 12.4 0.1 2.3 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein PAS_3 PF08447.12 PVD26546.1 - 9e-22 77.2 0.2 3.3e-15 56.1 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 PVD26546.1 - 1.5e-20 73.4 0.6 8.5e-15 54.9 0.2 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 PVD26546.1 - 1.1e-15 57.5 0.0 3.9e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PVD26546.1 - 2e-09 37.7 0.0 0.00048 20.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 PVD26546.1 - 3e-09 37.1 0.0 9.2e-05 22.6 0.0 2.8 3 0 0 3 3 3 2 PAS domain HIF-1a_CTAD PF08778.10 PVD26546.1 - 1.2e-07 31.2 0.1 3e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 PVD26546.1 - 2.5e-06 26.8 0.7 6.4e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 HLH PF00010.26 PVD26546.1 - 0.024 14.6 0.1 0.069 13.1 0.1 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain HNH_4 PF13395.6 PVD26546.1 - 0.04 13.8 0.0 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease SANTA PF09133.10 PVD26547.1 - 6.9e-17 61.7 0.0 2.2e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 PVD26547.1 - 9.7e-06 25.7 1.1 2.5e-05 24.3 1.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1299 PF06975.11 PVD26547.1 - 0.26 11.4 3.5 0.23 11.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Histone PF00125.24 PVD26548.1 - 8.5e-25 87.6 1.3 1e-24 87.4 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD26548.1 - 6e-07 29.7 1.1 9.2e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PVD26548.1 - 0.00061 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 PVD26548.1 - 0.0028 17.7 0.4 0.0032 17.5 0.4 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 PVD26548.1 - 0.092 12.4 0.9 6 6.5 0.5 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF1931 PF09123.11 PVD26548.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.24 PVD26549.1 - 1.6e-44 151.4 0.5 1.9e-44 151.2 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PVD26549.1 - 6.8e-05 23.0 0.1 9.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PVD26549.1 - 0.00028 21.2 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PVD26549.1 - 0.0094 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PVD26549.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 PVD26550.1 - 5.2e-21 74.1 1.1 1e-20 73.1 1.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PVD26550.1 - 1.6e-15 57.6 0.0 2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD26550.1 - 9.9e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fasciclin PF02469.22 PVD26551.1 - 7.9e-56 187.8 0.1 1.8e-30 105.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain VHP PF02209.19 PVD26551.1 - 0.026 14.6 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Villin headpiece domain Cation_efflux PF01545.21 PVD26552.1 - 1.1e-16 61.2 19.2 3.2e-16 59.7 19.2 1.8 1 1 0 1 1 1 1 Cation efflux family AAA PF00004.29 PVD26553.1 - 5.8e-73 243.5 0.2 1.5e-46 158.1 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD26553.1 - 1.7e-12 48.1 1.1 0.0031 17.9 0.0 4.7 2 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 PVD26553.1 - 9.9e-12 44.9 0.0 0.00011 22.0 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PVD26553.1 - 1.3e-09 38.2 2.6 0.0018 18.3 0.1 4.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD26553.1 - 1.7e-09 38.1 1.2 0.019 15.3 0.1 4.4 2 2 1 3 3 3 2 AAA domain Nucleolin_bd PF16725.5 PVD26553.1 - 1.2e-08 34.4 0.2 6.1e-07 29.0 0.0 2.8 2 0 0 2 2 2 1 Nucleolin binding domain AAA_33 PF13671.6 PVD26553.1 - 1.4e-08 35.0 0.0 0.0013 18.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 PVD26553.1 - 1.8e-08 34.7 0.0 2.7e-05 24.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 PVD26553.1 - 1.5e-07 31.1 0.0 0.00013 21.7 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain IstB_IS21 PF01695.17 PVD26553.1 - 2.4e-07 30.7 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 PVD26553.1 - 2.6e-07 31.2 1.7 0.044 14.3 0.0 4.0 3 1 0 3 3 3 2 ABC transporter RNA_helicase PF00910.22 PVD26553.1 - 4e-07 30.4 0.0 0.063 13.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 PVD26553.1 - 5e-07 30.3 0.0 0.009 16.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 PVD26553.1 - 6.3e-07 28.9 0.0 0.003 16.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 PVD26553.1 - 6.9e-07 28.9 0.2 0.054 12.9 0.0 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PVD26553.1 - 1.6e-06 27.8 2.1 3.7 7.1 0.0 4.4 2 2 1 4 4 4 1 AAA domain AAA_14 PF13173.6 PVD26553.1 - 2.1e-06 27.8 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PVD26553.1 - 4.2e-06 27.1 0.0 0.044 14.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 PVD26553.1 - 4.8e-06 26.6 2.7 0.015 15.3 0.0 3.9 3 1 1 4 4 4 2 Rad17 P-loop domain TsaE PF02367.17 PVD26553.1 - 2.5e-05 24.3 0.0 0.022 14.8 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PVD26553.1 - 3.4e-05 23.8 0.3 1 9.2 0.0 3.7 3 1 0 3 3 3 2 NACHT domain Viral_helicase1 PF01443.18 PVD26553.1 - 9.3e-05 22.3 0.3 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PVD26553.1 - 0.00013 21.6 0.0 0.085 12.4 0.0 3.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 PVD26553.1 - 0.00016 22.0 0.1 0.73 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PVD26553.1 - 0.00022 20.6 0.0 0.19 11.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 PVD26553.1 - 0.00039 20.5 0.0 0.095 12.8 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 PVD26553.1 - 0.00044 20.4 0.0 0.62 10.2 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 PVD26553.1 - 0.00093 19.6 7.4 0.055 13.9 0.0 4.0 5 0 0 5 5 3 1 AAA domain Sigma54_activat PF00158.26 PVD26553.1 - 0.0027 17.4 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 PVD26553.1 - 0.0028 16.9 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.22 PVD26553.1 - 0.0078 16.3 0.4 1.3 9.1 0.0 3.3 3 0 0 3 3 2 1 Shikimate kinase AAA_3 PF07726.11 PVD26553.1 - 0.01 15.7 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HycH PF07450.11 PVD26553.1 - 0.013 15.9 1.8 0.24 11.8 1.4 2.8 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH AAA_24 PF13479.6 PVD26553.1 - 0.014 15.2 0.0 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 PVD26553.1 - 0.019 14.7 0.9 6.8 6.4 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase Mu-like_Pro PF10123.9 PVD26553.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage I protein Parvo_NS1 PF01057.17 PVD26553.1 - 0.036 13.1 0.0 4.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CPT PF07931.12 PVD26553.1 - 0.043 13.7 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 PVD26553.1 - 0.049 13.1 0.0 6.4 6.2 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein ADK PF00406.22 PVD26553.1 - 0.066 13.3 0.1 2.2 8.4 0.0 2.9 2 0 0 2 2 2 0 Adenylate kinase AAA_29 PF13555.6 PVD26553.1 - 0.073 12.8 0.0 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 PVD26553.1 - 0.096 12.0 3.6 2.3 7.5 0.0 3.7 4 0 0 4 4 4 0 KaiC DUF2205 PF10224.9 PVD26553.1 - 0.37 10.8 3.6 0.45 10.6 1.8 2.1 1 1 0 1 1 1 0 Short coiled-coil protein CC2-LZ PF16516.5 PVD26553.1 - 0.67 10.4 8.1 3.5 8.1 8.1 2.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_11 PF13086.6 PVD26553.1 - 0.77 9.5 0.0 0.77 9.5 0.0 4.6 4 1 0 4 4 3 0 AAA domain DUF4407 PF14362.6 PVD26553.1 - 0.96 8.7 7.2 2.3 7.5 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD26553.1 - 3.5 7.1 13.1 0.31 10.6 4.7 2.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit AAA_23 PF13476.6 PVD26553.1 - 4.1 7.8 17.3 6.6 7.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain DUF1366 PF07104.11 PVD26553.1 - 7 6.4 6.4 8.5 6.1 0.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) Kinesin PF00225.23 PVD26554.1 - 1.8e-102 342.7 0.4 2.3e-102 342.4 0.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD26554.1 - 7.7e-27 94.1 0.0 1.5e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding GxGYxYP_N PF16216.5 PVD26554.1 - 0.052 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal FH2 PF02181.23 PVD26555.1 - 2.5e-91 306.6 12.7 2.6e-63 214.4 5.0 3.6 3 1 1 4 4 4 2 Formin Homology 2 Domain Drf_GBD PF06371.13 PVD26555.1 - 3.8e-44 150.5 0.1 3.8e-44 150.5 0.1 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PVD26555.1 - 1.9e-32 112.5 0.1 4.2e-31 108.1 0.0 4.6 5 1 1 6 6 6 2 Diaphanous FH3 Domain Peptidase_C13 PF01650.18 PVD26556.1 - 3e-86 289.1 5.3 7.9e-86 287.7 5.3 1.6 1 1 0 1 1 1 1 Peptidase C13 family AAA_23 PF13476.6 PVD26556.1 - 0.009 16.5 0.4 0.012 16.1 0.4 1.2 1 0 0 1 1 1 1 AAA domain RelB PF04221.12 PVD26556.1 - 0.018 15.0 0.0 0.069 13.1 0.0 1.9 1 0 0 1 1 1 0 RelB antitoxin MgsA_C PF12002.8 PVD26556.1 - 0.081 12.9 0.3 0.19 11.6 0.3 1.7 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF2722 PF10846.8 PVD26557.1 - 0.0084 15.1 16.1 0.0085 15.1 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PVD26557.1 - 0.049 13.2 21.5 0.049 13.2 21.5 1.1 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 PVD26557.1 - 0.093 11.4 17.6 0.095 11.4 17.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med3 PF11593.8 PVD26557.1 - 0.48 9.6 11.2 0.47 9.6 11.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 PVD26557.1 - 0.92 9.4 20.8 0.94 9.4 20.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TraT PF05818.12 PVD26557.1 - 1.1 8.9 8.8 1.3 8.7 8.8 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein FlaG PF03646.15 PVD26557.1 - 1.5 9.1 13.6 1.9 8.7 13.6 1.2 1 0 0 1 1 1 0 FlaG protein TERB2 PF15101.6 PVD26557.1 - 1.6 8.7 10.0 1.6 8.8 10.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FliP PF00813.20 PVD26557.1 - 3.8 7.4 4.0 3.8 7.3 4.0 1.1 1 0 0 1 1 1 0 FliP family eIF-3_zeta PF05091.12 PVD26557.1 - 4.8 6.0 13.9 5 6.0 13.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 PVD26557.1 - 5.1 6.8 8.9 5 6.8 8.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5345 PF17280.2 PVD26557.1 - 5.6 7.0 10.4 17 5.5 10.4 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5345) Neur_chan_memb PF02932.16 PVD26557.1 - 7.2 6.6 7.1 7.3 6.6 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.8 PVD26557.1 - 7.8 5.3 12.2 9.1 5.1 12.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dicty_REP PF05086.12 PVD26557.1 - 8 4.3 12.5 8.1 4.3 12.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein XRN_M PF17846.1 PVD26557.1 - 9.9 5.0 11.8 11 4.9 11.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain KDZ PF18758.1 PVD26558.1 - 2.5e-16 60.0 0.0 1.5e-15 57.4 0.0 2.2 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 PVD26558.1 - 3.5e-05 23.9 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 PVD26558.1 - 0.00032 20.8 0.0 0.00078 19.6 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 PVD26558.1 - 0.016 15.0 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases bMG6 PF17962.1 PVD26558.1 - 0.052 13.7 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 Dodecin PF07311.12 PVD26559.1 - 0.077 13.3 1.4 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 Dodecin SpoVS PF04232.12 PVD26559.1 - 0.18 11.6 1.9 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) Hyd_WA PF06462.12 PVD26560.1 - 8.5e-13 48.1 10.5 3.4e-07 30.1 0.4 5.4 6 0 0 6 6 6 3 Propeller Hyd_WA PF06462.12 PVD26561.1 - 1.2e-33 114.7 26.0 4.6e-08 32.9 0.1 9.9 9 1 0 9 9 9 7 Propeller BBS2_N PF14781.6 PVD26561.1 - 0.19 11.6 0.0 35 4.4 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Hyd_WA PF06462.12 PVD26562.1 - 2.2e-13 49.9 10.2 3.6e-07 30.0 0.4 4.0 4 1 0 4 4 4 3 Propeller Hyd_WA PF06462.12 PVD26563.1 - 5.7e-25 87.0 17.6 5.1e-10 39.2 0.6 6.7 7 1 0 7 7 7 5 Propeller Tachylectin PF14517.6 PVD26563.1 - 0.13 11.8 9.8 0.13 11.8 0.3 2.9 1 1 1 3 3 3 0 Tachylectin Hyd_WA PF06462.12 PVD26564.1 - 2.3e-28 97.9 21.0 1.6e-06 28.0 3.2 6.3 6 1 0 6 6 6 5 Propeller Collar PF07484.12 PVD26564.1 - 0.0036 17.3 0.8 1.3 9.0 0.0 3.6 4 0 0 4 4 4 2 Phage Tail Collar Domain RcnB PF11776.8 PVD26564.1 - 0.1 12.6 13.1 6.4 6.9 0.8 5.3 6 0 0 6 6 6 0 Nickel/cobalt transporter regulator Hyd_WA PF06462.12 PVD26565.1 - 2.5e-19 68.9 8.9 2.5e-06 27.4 0.0 5.3 5 1 0 5 5 5 3 Propeller RcnB PF11776.8 PVD26565.1 - 0.023 14.7 5.1 13 5.9 0.0 4.4 4 0 0 4 4 4 0 Nickel/cobalt transporter regulator Hyd_WA PF06462.12 PVD26566.1 - 1.9e-17 62.9 21.8 1.4e-08 34.5 1.0 6.3 6 1 0 6 6 6 5 Propeller RcnB PF11776.8 PVD26566.1 - 0.95 9.6 5.5 1e+02 3.1 0.0 4.3 4 0 0 4 4 4 0 Nickel/cobalt transporter regulator Hyd_WA PF06462.12 PVD26567.1 - 0.00027 20.9 0.0 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Propeller Hyd_WA PF06462.12 PVD26568.1 - 1.1e-13 50.9 6.5 1.4e-06 28.2 0.1 4.9 5 0 0 5 5 5 3 Propeller Hyd_WA PF06462.12 PVD26569.1 - 8.1e-23 80.1 9.7 8.5e-08 32.1 0.1 6.3 6 1 0 6 6 6 5 Propeller RcnB PF11776.8 PVD26569.1 - 0.58 10.3 7.9 2.8 8.0 0.4 4.6 5 1 0 5 5 5 0 Nickel/cobalt transporter regulator Myosin_head PF00063.21 PVD26570.1 - 1.5e-222 740.6 4.1 2.1e-222 740.1 4.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 PVD26570.1 - 7.1e-45 151.9 16.0 2.6e-27 95.4 1.0 3.2 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.18 PVD26570.1 - 2.5e-21 76.2 0.0 1.4e-12 48.1 0.0 4.2 2 1 1 3 3 3 3 FERM central domain RA PF00788.23 PVD26570.1 - 2e-06 28.4 0.0 6.4e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 PVD26570.1 - 2.7e-06 26.7 19.6 0.0058 16.3 1.7 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif FERM_N PF09379.10 PVD26570.1 - 1.3e-05 25.0 0.1 0.075 13.0 0.0 2.9 2 0 0 2 2 2 2 FERM N-terminal domain Ras_bdg_2 PF14847.6 PVD26570.1 - 0.0019 18.5 0.1 0.048 14.0 0.0 3.0 3 0 0 3 3 3 1 Ras-binding domain of Byr2 AAA_16 PF13191.6 PVD26570.1 - 0.088 13.2 0.9 0.29 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Radial_spoke_3 PF06098.11 PVD26570.1 - 0.57 9.4 14.4 1.2 8.3 14.4 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 Memo PF01875.17 PVD26573.1 - 1.2e-48 165.6 0.0 1.5e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Acetyltransf_1 PF00583.25 PVD26574.1 - 2.5e-05 24.5 0.0 5.1e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PVD26574.1 - 9.4e-05 22.3 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PVD26574.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD26574.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sds3 PF08598.11 PVD26575.1 - 1.4e-05 25.2 4.2 1.4e-05 25.2 4.2 2.1 1 1 1 2 2 2 1 Sds3-like Fibrinogen_C PF00147.18 PVD26577.1 - 3.4e-29 102.2 0.1 1.5e-25 90.3 0.0 2.3 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain bZIP_2 PF07716.15 PVD26579.1 - 2.3e-16 59.6 11.6 3.1e-16 59.2 11.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD26579.1 - 1.3e-05 25.2 8.4 1.9e-05 24.6 8.4 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD26579.1 - 0.027 15.0 4.6 0.038 14.5 4.6 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor DDE_1 PF03184.19 PVD26582.1 - 4.6e-36 124.1 0.0 1.2e-35 122.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PVD26582.1 - 2.1e-15 56.5 0.0 7.4e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 PVD26582.1 - 8.6e-07 28.6 0.0 2.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 PVD26582.1 - 0.05 14.2 0.4 0.29 11.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 PVD26582.1 - 0.064 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Ank_4 PF13637.6 PVD26585.1 - 6.3e-17 61.7 0.2 1.2e-12 48.0 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26585.1 - 6.7e-15 55.5 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26585.1 - 6.9e-15 53.7 0.3 4.5e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SH3_1 PF00018.28 PVD26585.1 - 8.9e-13 47.6 0.4 1.8e-12 46.6 0.4 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 PVD26585.1 - 1.3e-12 47.5 0.1 3.2e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PVD26585.1 - 1.5e-12 47.4 0.8 2.3e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.6 PVD26585.1 - 9.5e-11 41.4 0.1 2.2e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD26585.1 - 1.8e-09 37.1 0.1 6e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF1843 PF08898.10 PVD26585.1 - 0.43 11.1 5.0 0.72 10.4 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) AAA PF00004.29 PVD26586.1 - 1.1e-42 145.5 0.0 2.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD26586.1 - 4e-07 30.6 0.1 0.0014 19.1 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PVD26586.1 - 5.9e-06 26.3 0.0 5.8e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PVD26586.1 - 6.9e-06 26.3 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PVD26586.1 - 1.3e-05 25.4 0.6 0.0019 18.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 PVD26586.1 - 4.3e-05 23.3 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PVD26586.1 - 0.0017 18.9 0.0 0.0095 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PVD26586.1 - 0.0031 17.7 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD26586.1 - 0.0032 17.0 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD26586.1 - 0.0034 17.2 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 PVD26586.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PVD26586.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PVD26586.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PVD26586.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 PVD26586.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 PVD26586.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 PVD26586.1 - 0.025 15.3 0.5 0.063 14.0 0.5 1.7 1 0 0 1 1 1 0 Occludin homology domain GAS PF13851.6 PVD26586.1 - 0.039 13.3 5.2 0.069 12.5 5.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RNA_helicase PF00910.22 PVD26586.1 - 0.05 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ThiD2 PF17792.1 PVD26586.1 - 0.052 14.0 0.5 0.2 12.1 0.2 2.0 2 0 0 2 2 2 0 ThiD2 family AAA_11 PF13086.6 PVD26586.1 - 0.052 13.3 0.2 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PVD26586.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 PVD26586.1 - 0.085 12.4 0.3 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PVD26586.1 - 0.092 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PVD26586.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain CENP-Q PF13094.6 PVD26586.1 - 0.27 11.4 5.2 1.2 9.3 5.2 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ion_trans_2 PF07885.16 PVD26588.1 - 5.1e-19 68.0 16.5 9e-15 54.4 7.3 2.5 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.31 PVD26588.1 - 0.037 13.3 9.6 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 Ion transport protein DUF4044 PF13253.6 PVD26588.1 - 0.88 9.1 6.2 1.7 8.3 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Ion_trans_2 PF07885.16 PVD26590.1 - 4.8e-05 23.3 0.1 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 1 Ion channel FAD_binding_3 PF01494.19 PVD26591.1 - 1.1e-14 54.4 0.0 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 PVD26591.1 - 0.0017 17.5 0.0 0.012 14.6 0.0 2.1 2 1 0 2 2 2 1 Squalene epoxidase RVT_1 PF00078.27 PVD26592.1 - 3.9e-24 85.4 0.1 4.7e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF29 PF01724.16 PVD26592.1 - 0.0017 18.6 0.1 0.0024 18.1 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function DUF29 FAD_binding_3 PF01494.19 PVD26593.1 - 4.2e-12 46.0 0.0 4.6e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Kunitz_BPTI PF00014.23 PVD26595.1 - 2.8e-18 65.9 8.8 2.8e-18 65.9 8.8 2.2 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Ank_2 PF12796.7 PVD26596.1 - 3e-13 50.2 0.0 6.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26596.1 - 1.9e-11 43.1 0.0 0.00027 21.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PVD26596.1 - 6e-11 42.6 0.0 2.9e-07 30.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD26596.1 - 1.4e-09 38.0 0.0 0.0017 18.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD26596.1 - 2.1e-08 34.3 0.0 4e-06 27.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_20b PF02838.15 PVD26596.1 - 1.2e-07 32.6 0.0 3.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Dynein_light PF01221.18 PVD26597.1 - 2e-43 146.6 1.6 2.2e-43 146.5 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 PVD26598.1 - 2e-43 146.6 1.6 2.2e-43 146.5 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 PVD26599.1 - 1.8e-43 146.8 0.7 2e-43 146.6 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 PVD26599.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 48 Cyclin PF08613.11 PVD26600.1 - 5.7 7.3 5.9 1.2 9.4 0.3 2.4 1 1 1 2 2 2 0 Cyclin cNMP_binding PF00027.29 PVD26601.1 - 3.5e-17 62.2 0.0 7.1e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 PVD26601.1 - 3e-14 52.9 6.1 4.3e-14 52.3 6.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD26601.1 - 0.00027 20.8 5.8 0.00051 19.9 5.8 1.5 1 0 0 1 1 1 1 Ion channel Selenoprotein_S PF06936.11 PVD26601.1 - 0.31 10.8 3.7 1.3 8.8 3.7 2.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) ADIP PF11559.8 PVD26601.1 - 0.39 10.8 4.6 1.7 8.7 4.6 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PX PF00787.24 PVD26602.1 - 3.6e-17 62.4 0.4 9.9e-17 61.0 0.4 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 PVD26602.1 - 2.9e-12 46.6 18.6 1.3e-09 38.0 17.9 2.8 1 1 1 2 2 2 1 Vps5 C terminal like TMEM51 PF15345.6 PVD26602.1 - 0.052 13.4 2.1 0.088 12.6 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 BLYB PF05289.11 PVD26602.1 - 0.45 10.7 8.0 0.065 13.5 2.6 2.4 2 1 1 3 3 3 0 Borrelia hemolysin accessory protein FlxA PF14282.6 PVD26602.1 - 4.5 7.3 8.7 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 FlxA-like protein Claudin_2 PF13903.6 PVD26603.1 - 0.16 11.7 15.5 1.2 8.8 15.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF973 PF06157.11 PVD26603.1 - 0.16 11.0 11.6 0.2 10.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) ThrE PF06738.12 PVD26603.1 - 0.16 11.3 10.2 0.19 11.0 10.2 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter PelG PF16933.5 PVD26603.1 - 0.4 9.5 10.8 0.45 9.3 10.8 1.0 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) DUF2070 PF09843.9 PVD26603.1 - 0.68 8.1 6.4 0.82 7.9 6.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Clc-like PF07062.12 PVD26603.1 - 2.2 7.7 10.9 16 4.9 10.9 1.9 1 1 0 1 1 1 0 Clc-like DUF3810 PF12725.7 PVD26603.1 - 2.9 7.2 4.6 2.8 7.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4191 PF13829.6 PVD26603.1 - 3 7.1 8.1 1 8.7 5.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF2304 PF10066.9 PVD26603.1 - 3.7 7.8 9.7 9 6.6 9.7 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF3382 PF11862.8 PVD26603.1 - 3.9 7.8 10.6 0.22 11.8 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF4229 PF14012.6 PVD26603.1 - 4.3 7.5 11.9 0.35 11.0 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) MARVEL PF01284.23 PVD26603.1 - 4.8 7.2 12.1 11 6.0 12.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain PMP22_Claudin PF00822.20 PVD26603.1 - 4.8 7.0 14.1 10 6.0 14.1 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family S_4TM PF18159.1 PVD26603.1 - 5.1 6.3 5.2 0.9 8.8 1.4 1.6 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain DUF2061 PF09834.9 PVD26603.1 - 5.9 7.5 11.7 0.74 10.4 6.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) TPR_1 PF00515.28 PVD26606.1 - 6.3e-48 158.7 18.8 2.6e-07 30.2 1.1 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26606.1 - 1.2e-36 121.9 15.3 1.4e-06 27.9 1.5 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 PVD26606.1 - 1.4e-29 101.4 12.7 4.9e-12 45.3 0.4 6.1 4 1 2 6 6 6 4 TPR repeat TPR_8 PF13181.6 PVD26606.1 - 9.1e-27 91.0 17.0 0.00012 22.0 0.4 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 PVD26606.1 - 5.4e-19 68.3 10.1 5.7e-11 42.5 0.2 5.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26606.1 - 9.5e-18 64.5 8.6 8.8e-06 26.1 0.1 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 PVD26606.1 - 3.2e-17 61.8 1.3 0.033 15.0 0.0 6.5 3 3 4 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD26606.1 - 5.2e-17 62.2 0.8 0.00039 21.0 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 PVD26606.1 - 1.6e-16 59.9 4.0 6.1e-16 58.1 4.0 2.1 1 0 0 1 1 1 1 STI1 domain TPR_17 PF13431.6 PVD26606.1 - 1.2e-15 56.6 11.9 1.7e-05 24.9 0.0 6.8 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26606.1 - 6.9e-15 53.9 5.3 0.0011 18.9 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD26606.1 - 2.1e-11 43.8 0.0 0.005 17.0 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD26606.1 - 7.8e-11 41.9 11.1 0.054 14.2 0.1 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD26606.1 - 2.6e-09 36.6 6.2 0.0098 15.7 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD26606.1 - 8.8e-08 32.3 9.4 0.0061 16.8 2.6 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 PVD26606.1 - 2.5e-06 26.7 4.0 0.056 12.4 0.0 3.6 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 PVD26606.1 - 3.5e-05 23.2 3.0 0.012 14.9 0.3 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 PVD26606.1 - 0.00018 21.6 1.8 0.074 13.1 0.3 2.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 PVD26606.1 - 0.00026 20.7 9.2 2.2 7.9 0.1 4.2 2 1 1 4 4 4 1 Tetratricopeptide repeat-like domain DUF627 PF04781.12 PVD26606.1 - 0.00031 20.7 2.9 3.6 7.6 0.3 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF627) TPR_MalT PF17874.1 PVD26606.1 - 0.0051 16.2 0.4 0.013 14.9 0.4 1.7 1 1 0 1 1 1 1 MalT-like TPR region Fis1_TPR_C PF14853.6 PVD26606.1 - 0.0066 16.5 8.9 0.32 11.1 0.1 5.0 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 PVD26606.1 - 0.014 15.6 1.0 3 8.3 0.0 4.2 4 0 0 4 4 4 0 PPR repeat RPN7 PF10602.9 PVD26606.1 - 0.025 14.3 8.8 0.025 14.3 2.3 3.0 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_4 PF07721.14 PVD26606.1 - 0.051 14.2 0.0 4.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4363 PF14276.6 PVD26606.1 - 0.052 13.7 1.4 3 8.0 0.2 3.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4363) NRBF2_MIT PF17169.4 PVD26606.1 - 0.053 13.7 1.7 0.45 10.8 0.7 2.7 2 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 Mob_Pre PF01076.19 PVD26606.1 - 0.06 13.2 4.0 0.079 12.8 0.4 2.2 1 1 1 2 2 2 0 Plasmid recombination enzyme DUF357 PF04010.13 PVD26606.1 - 0.084 13.0 0.2 0.084 13.0 0.2 3.6 3 1 1 4 4 3 0 Protein of unknown function (DUF357) FAT PF02259.23 PVD26606.1 - 0.094 11.9 4.2 1.3 8.1 4.1 2.4 1 1 0 1 1 1 0 FAT domain DUF2240 PF09999.9 PVD26606.1 - 0.15 11.7 2.5 0.26 10.9 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2240) ChAPs PF09295.10 PVD26606.1 - 0.16 10.9 2.8 16 4.4 0.0 3.0 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Ciart PF15673.5 PVD26606.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor MIT PF04212.18 PVD26606.1 - 0.19 11.8 16.8 2.9 8.0 0.0 5.6 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 PVD26606.1 - 0.25 11.8 5.8 42 4.6 0.9 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation DUF5113 PF17140.4 PVD26606.1 - 0.36 10.6 4.9 5.5 6.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) Alpha-amylase PF00128.24 PVD26607.1 - 1.8e-45 156.0 4.4 6.6e-45 154.1 4.4 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 PVD26607.1 - 1.9e-29 101.0 0.3 3.6e-29 100.1 0.3 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus DUF4389 PF14333.6 PVD26607.1 - 4.1 7.4 6.4 8.5 6.4 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) 2OG-FeII_Oxy_2 PF13532.6 PVD26608.1 - 3.8e-31 108.8 0.0 8e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3586 PF12131.8 PVD26608.1 - 0.23 11.7 5.3 0.22 11.8 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3586) RRM_1 PF00076.22 PVD26609.1 - 1.5e-18 66.4 0.1 1.7e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD26609.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RL PF17797.1 PVD26609.1 - 0.066 13.2 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 RL domain Ank_2 PF12796.7 PVD26610.1 - 6.3e-88 289.5 32.7 5.2e-18 65.4 0.3 7.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD26610.1 - 2e-70 232.3 26.9 3.9e-13 49.6 0.3 9.9 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 PVD26610.1 - 5.4e-65 213.2 36.0 1.7e-06 28.2 0.0 14.1 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 PVD26610.1 - 2.6e-56 181.0 34.0 6.2e-05 23.1 0.0 14.7 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 PVD26610.1 - 3.4e-50 167.4 34.3 5.7e-07 29.7 0.2 12.2 4 2 8 12 12 12 11 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD26610.1 - 0.00028 21.2 2.5 0.00093 19.5 2.5 2.0 1 0 0 1 1 1 1 SOCS box DUF2520 PF10728.9 PVD26610.1 - 0.45 10.3 5.7 0.5 10.1 1.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2520) AAA PF00004.29 PVD26611.1 - 4.2e-62 208.4 0.0 4.3e-47 159.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD26611.1 - 4.7e-11 43.4 0.1 0.0055 17.1 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 PVD26611.1 - 1.5e-08 34.5 0.2 0.00041 20.1 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PVD26611.1 - 2e-07 31.1 0.1 0.014 15.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 PVD26611.1 - 7.3e-07 29.2 0.0 0.09 12.8 0.0 3.5 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PVD26611.1 - 4e-06 27.2 0.2 0.036 14.3 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.6 PVD26611.1 - 7.2e-06 25.9 1.1 0.083 12.6 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 PVD26611.1 - 9.8e-06 25.3 0.2 0.018 14.6 0.1 3.6 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 PVD26611.1 - 2.4e-05 24.7 0.0 0.054 13.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase TIP49 PF06068.13 PVD26611.1 - 2.5e-05 23.6 0.2 0.0081 15.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 PVD26611.1 - 2.9e-05 24.6 0.1 0.084 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PVD26611.1 - 3.2e-05 24.1 0.0 0.068 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 PVD26611.1 - 6e-05 23.0 0.3 0.0006 19.8 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 PVD26611.1 - 8.6e-05 22.7 0.0 0.33 11.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 PVD26611.1 - 8.7e-05 22.8 0.1 0.4 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PVD26611.1 - 0.00017 21.7 0.0 0.87 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 PVD26611.1 - 0.00024 21.0 0.0 0.88 9.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PVD26611.1 - 0.00025 21.0 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 PVD26611.1 - 0.0003 20.4 0.0 0.6 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 PVD26611.1 - 0.00034 20.1 0.1 0.025 14.0 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PVD26611.1 - 0.00061 19.6 0.1 0.03 14.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 PVD26611.1 - 0.00074 19.5 0.1 0.063 13.2 0.1 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 PVD26611.1 - 0.00079 19.4 0.1 1.6 8.6 0.0 3.0 3 1 0 4 4 3 1 NACHT domain DUF815 PF05673.13 PVD26611.1 - 0.0011 18.2 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 PVD26611.1 - 0.0015 18.9 0.4 2.3 8.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 PVD26611.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TniB PF05621.11 PVD26611.1 - 0.0038 16.7 0.1 0.97 8.8 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein Sigma54_activat PF00158.26 PVD26611.1 - 0.0052 16.5 0.0 1 9.1 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 PVD26611.1 - 0.0054 16.7 0.0 0.44 10.4 0.0 3.1 3 1 0 3 3 2 1 RsgA GTPase Sigma54_activ_2 PF14532.6 PVD26611.1 - 0.006 16.7 0.0 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 PVD26611.1 - 0.0077 15.9 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PVD26611.1 - 0.0078 15.5 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 PVD26611.1 - 0.009 16.5 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 PVD26611.1 - 0.013 14.8 0.1 0.54 9.6 0.0 2.7 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 PVD26611.1 - 0.025 13.7 0.0 3.9 6.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 PVD26611.1 - 0.027 14.9 0.0 3.4 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PVD26611.1 - 0.045 13.2 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 PVD26611.1 - 0.052 13.5 0.0 14 5.5 0.0 2.9 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 PVD26611.1 - 0.058 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SRP54 PF00448.22 PVD26611.1 - 0.14 11.8 0.1 0.93 9.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 PVD26611.1 - 0.19 11.4 0.2 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.15 PVD26612.1 - 5.3e-51 172.7 0.3 1.1e-50 171.7 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 PVD26612.1 - 2e-40 138.5 1.1 2.1e-35 122.1 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 PVD26612.1 - 5.9e-18 65.6 0.6 4e-09 36.9 0.1 3.2 2 1 1 3 3 3 2 Helicase C-terminal domain DnaB_2 PF07261.11 PVD26612.1 - 0.015 15.0 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment Phage_Gp17 PF17549.2 PVD26612.1 - 0.02 14.9 0.2 0.99 9.4 0.4 2.5 2 0 0 2 2 2 0 Gene Product 17 MtaB PF12176.8 PVD26612.1 - 0.19 10.5 0.7 0.34 9.6 0.7 1.3 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit DUF3341 PF11821.8 PVD26613.1 - 0.8 9.3 3.9 1 9.0 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) AAA_33 PF13671.6 PVD26614.1 - 5.9e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD26614.1 - 6.2e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 PVD26614.1 - 9e-05 21.9 0.0 9e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase KTI12 PF08433.10 PVD26614.1 - 0.00032 20.2 0.0 0.00079 18.9 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 PVD26614.1 - 0.043 13.1 0.1 0.14 11.4 0.1 1.8 1 1 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 PVD26615.1 - 6.2e-09 35.6 0.0 8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD26615.1 - 0.0041 16.5 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PVD26616.1 - 1.8e-22 80.0 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26616.1 - 3.4e-11 42.9 0.0 4.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD26616.1 - 0.00082 18.4 0.1 0.0046 15.9 0.1 1.9 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 PVD26616.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CUB PF00431.20 PVD26617.1 - 3e-07 30.8 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain Herpes_gE PF02480.16 PVD26617.1 - 0.026 13.3 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CUB PF00431.20 PVD26618.1 - 1.2e-07 32.0 0.0 2.3e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 CUB domain CUB PF00431.20 PVD26619.1 - 7.7e-14 52.0 0.2 1.9e-13 50.7 0.2 1.7 1 0 0 1 1 1 1 CUB domain CUE PF02845.16 PVD26619.1 - 0.013 15.2 0.1 2.1 8.1 0.0 3.7 4 0 0 4 4 4 0 CUE domain Orf78 PF06024.12 PVD26619.1 - 0.23 11.8 0.9 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) IBR PF01485.21 PVD26619.1 - 0.68 10.2 41.6 0.027 14.7 3.1 4.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain BUD22 PF09073.10 PVD26619.1 - 1.1 8.5 9.4 0.66 9.3 6.9 1.9 2 0 0 2 2 2 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 PVD26619.1 - 3.3 7.9 16.4 16 5.7 16.4 2.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 WSC PF01822.19 PVD26621.1 - 1.3e-15 57.3 19.6 3.5e-09 36.7 2.3 2.2 2 0 0 2 2 2 2 WSC domain Patched PF02460.18 PVD26622.1 - 0.014 13.5 0.6 0.019 13.0 0.6 1.1 1 0 0 1 1 1 0 Patched family Patched PF02460.18 PVD26623.1 - 4.8e-60 203.6 73.9 7.4e-20 70.7 4.5 5.5 5 0 0 5 5 5 5 Patched family Sterol-sensing PF12349.8 PVD26623.1 - 3.6e-22 78.9 80.0 4.5e-12 46.1 11.5 6.3 6 1 0 6 6 6 4 Sterol-sensing domain of SREBP cleavage-activation PSI_PsaJ PF01701.18 PVD26623.1 - 8.9e-06 26.1 4.8 0.048 14.2 0.5 3.8 2 0 0 2 2 2 2 Photosystem I reaction centre subunit IX / PsaJ DUF1829 PF08862.10 PVD26623.1 - 0.00069 20.0 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF1829 DGCR6 PF07324.11 PVD26623.1 - 0.13 11.9 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein Wzy_C PF04932.15 PVD26623.1 - 0.85 9.2 0.0 0.85 9.2 0.0 8.3 9 1 0 9 9 9 0 O-Antigen ligase Beta-lactamase PF00144.24 PVD26624.1 - 3.7e-22 79.0 0.0 5.5e-19 68.6 0.0 2.2 1 1 1 2 2 2 2 Beta-lactamase MCM PF00493.23 PVD26625.1 - 4.2e-100 333.5 0.0 6.8e-100 332.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PVD26625.1 - 9.4e-39 132.1 0.5 2.4e-38 130.8 0.5 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PVD26625.1 - 8.9e-29 99.8 0.7 4.7e-28 97.5 0.7 2.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PVD26625.1 - 1.7e-18 67.1 0.4 6.3e-18 65.3 0.4 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PVD26625.1 - 8e-06 25.4 0.0 0.00083 18.8 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PVD26625.1 - 5.3e-05 23.2 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PVD26625.1 - 0.035 14.0 0.0 0.087 12.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PVD26625.1 - 0.082 12.6 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain LRR_6 PF13516.6 PVD26627.1 - 3.3e-20 70.4 24.1 5e-05 23.0 0.3 7.9 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 PVD26627.1 - 4.5e-08 32.6 1.7 3.7 8.5 0.0 6.6 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 PVD26627.1 - 6e-05 22.7 18.4 0.013 15.2 2.9 5.2 2 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PVD26627.1 - 7.3e-05 23.1 14.4 0.095 13.2 0.1 4.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD26628.1 - 0.00023 21.0 8.2 2.4 8.4 0.1 6.3 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 PVD26628.1 - 0.0034 17.7 2.5 2.5 9.0 0.5 5.5 5 1 0 5 5 5 1 Leucine Rich Repeat DUF4667 PF15700.5 PVD26628.1 - 0.028 14.5 12.0 0.039 14.0 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) PI3K_1B_p101 PF10486.9 PVD26628.1 - 0.06 11.1 15.6 0.087 10.6 15.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LRR_4 PF12799.7 PVD26628.1 - 0.34 11.4 6.0 24 5.5 0.0 4.5 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) SR-25 PF10500.9 PVD26628.1 - 0.42 10.2 25.5 0.6 9.7 25.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4820 PF16091.5 PVD26628.1 - 0.47 9.8 6.8 0.76 9.1 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPP4R2 PF09184.11 PVD26628.1 - 1.9 8.0 14.3 2.5 7.6 14.3 1.1 1 0 0 1 1 1 0 PPP4R2 Macoilin PF09726.9 PVD26628.1 - 4.8 5.6 16.8 6.4 5.2 16.8 1.1 1 0 0 1 1 1 0 Macoilin family tRNA-synt_1b PF00579.25 PVD26629.1 - 3.3e-25 89.0 0.0 6.3e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4455 PF14643.6 PVD26629.1 - 0.049 12.3 0.1 0.07 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) WD40 PF00400.32 PVD26630.1 - 3.4e-17 62.5 6.1 0.00017 22.3 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26630.1 - 4.4e-08 33.3 0.0 0.057 13.7 0.0 3.3 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PVD26630.1 - 0.062 13.8 0.1 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain Thyroglobulin_1 PF00086.18 PVD26631.1 - 7.1e-32 108.9 18.4 2.1e-17 62.5 4.6 4.4 6 0 0 6 6 6 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 PVD26631.1 - 2.6e-22 79.3 9.7 6.3e-12 45.8 2.2 2.7 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 PVD26631.1 - 1.5e-08 33.6 0.0 1.5 8.5 0.0 4.4 4 0 0 4 4 4 4 EF hand Kazal_2 PF07648.15 PVD26631.1 - 1.2e-07 31.7 8.0 2.3e-07 30.8 6.2 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 PVD26631.1 - 6.4e-07 28.8 0.3 2.7 8.2 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain Kazal_1 PF00050.21 PVD26631.1 - 2.2e-06 27.6 3.6 2.2e-06 27.6 3.6 4.5 5 0 0 5 5 5 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 PVD26631.1 - 7.7e-05 23.1 4.3 0.053 14.0 0.6 3.3 2 1 0 3 3 3 1 EF-hand domain pair DIRP PF06584.13 PVD26631.1 - 0.0074 16.4 3.9 0.41 10.8 1.1 2.8 2 0 0 2 2 2 1 DIRP EF-hand_5 PF13202.6 PVD26631.1 - 0.061 12.8 0.8 3.4 7.3 0.0 3.7 4 0 0 4 4 4 0 EF hand Glyco_hydro_10 PF00331.20 PVD26633.1 - 5e-44 150.7 0.3 7.3e-44 150.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26633.1 - 4.6e-07 30.2 0.5 0.00081 19.7 0.5 2.4 1 1 0 1 1 1 1 Carbohydrate binding domain DM13 PF10517.9 PVD26633.1 - 0.018 15.6 0.8 1.1 9.9 0.0 2.7 2 1 1 3 3 3 0 Electron transfer DM13 Glyco_hydro_10 PF00331.20 PVD26634.1 - 7.8e-37 127.1 0.0 1.6e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26634.1 - 3.2e-08 33.9 0.0 5e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26634.1 - 0.0027 17.3 0.0 0.11 12.0 0.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolase catalytic core DUF1087 PF06465.13 PVD26634.1 - 0.11 12.5 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) YcaO_C PF18381.1 PVD26634.1 - 0.12 12.3 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 YcaO cyclodehydratase C-terminal domain Glyco_hydro_10 PF00331.20 PVD26635.1 - 2.5e-20 72.9 0.1 3.3e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26635.1 - 5e-07 30.1 0.0 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain WSC PF01822.19 PVD26636.1 - 3.6e-20 71.9 13.2 1.5e-13 50.7 0.7 3.3 4 0 0 4 4 4 2 WSC domain Ion_trans PF00520.31 PVD26637.1 - 4.4e-14 52.3 17.5 1.4e-13 50.6 17.5 1.8 1 1 0 1 1 1 1 Ion transport protein LSDAT_euk PF18139.1 PVD26637.1 - 1.7e-09 37.4 0.4 7.5e-09 35.4 0.0 2.2 3 0 0 3 3 3 1 SLOG in TRPM LSDAT_prok PF18171.1 PVD26637.1 - 4.9e-07 29.2 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote DUF4105 PF13387.6 PVD26637.1 - 0.04 13.6 0.2 1.6 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) CitMHS PF03600.16 PVD26637.1 - 0.51 9.5 4.1 0.92 8.6 4.1 1.3 1 0 0 1 1 1 0 Citrate transporter DsrC PF04358.13 PVD26637.1 - 1.1 9.8 6.6 0.35 11.4 1.8 2.8 3 0 0 3 3 3 0 DsrC like protein NPV_P10 PF05531.12 PVD26637.1 - 2.8 8.5 7.4 27 5.3 0.3 3.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BTB PF00651.31 PVD26638.1 - 5.3e-18 65.3 0.1 1.8e-17 63.6 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD26638.1 - 4.6e-11 42.7 0.7 4.6e-11 42.7 0.7 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 PVD26638.1 - 2.9e-09 36.9 0.0 3.9e-06 27.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD26638.1 - 1.8e-07 31.0 0.1 0.0029 17.6 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD26638.1 - 1e-06 28.2 0.0 0.0001 21.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 PVD26638.1 - 1e-06 28.8 0.0 0.013 15.8 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD26638.1 - 0.0015 18.5 0.0 0.0053 16.7 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Meis_PKNOX_N PF16493.5 PVD26639.1 - 1.6e-43 146.9 0.4 2.6e-43 146.3 0.4 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 PVD26639.1 - 1.2e-20 73.1 0.7 2.2e-20 72.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD26639.1 - 2.1e-08 33.9 0.3 4.8e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 Homeodomain SSP160 PF06933.11 PVD26646.1 - 0.004 15.4 11.0 0.0042 15.4 11.0 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 PVD26646.1 - 0.13 12.7 10.3 0.2 12.1 10.3 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.12 PVD26646.1 - 0.42 8.5 5.6 0.53 8.2 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 PVD26646.1 - 1.8 6.6 7.5 2 6.4 7.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PT PF04886.12 PVD26647.1 - 2.2 7.9 5.1 0.84 9.2 0.2 2.1 2 0 0 2 2 2 0 PT repeat GAPES2 PF17156.4 PVD26648.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Met_10 PF02475.16 PVD26652.1 - 2.4e-59 200.5 0.0 3.6e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 PVD26652.1 - 0.0036 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 PVD26652.1 - 0.0052 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 PVD26652.1 - 0.041 13.3 0.0 0.087 12.2 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 PVD26652.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Forkhead PF00250.18 PVD26655.1 - 1.5e-28 98.9 0.0 2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Forkhead domain Diphtheria_C PF02763.14 PVD26655.1 - 0.059 13.0 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 Diphtheria toxin, C domain Forkhead PF00250.18 PVD26656.1 - 8.1e-39 131.8 0.1 1.4e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain Diphtheria_C PF02763.14 PVD26656.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain Forkhead PF00250.18 PVD26657.1 - 1.5e-33 114.9 0.1 2.7e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain MAT1 PF06391.13 PVD26658.1 - 3e-61 206.8 17.2 3.9e-61 206.5 17.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF501 PF04417.12 PVD26658.1 - 0.047 13.5 3.0 0.092 12.5 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) PSII_Pbs27 PF13326.6 PVD26658.1 - 0.058 13.7 0.9 0.11 12.8 0.9 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF16 PF01519.16 PVD26658.1 - 1.5 9.3 10.9 1.6 9.2 9.7 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Ion_trans_2 PF07885.16 PVD26659.1 - 8.3e-36 121.8 15.3 8e-18 64.2 1.4 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 PVD26659.1 - 1e-06 28.2 3.8 0.00033 20.0 0.0 2.2 1 1 1 2 2 2 2 Ion transport protein Reticulon PF02453.17 PVD26659.1 - 0.027 14.4 0.0 0.027 14.4 0.0 2.5 3 1 0 3 3 3 0 Reticulon LRR_4 PF12799.7 PVD26660.1 - 6.1e-09 36.0 8.0 0.00044 20.6 0.2 4.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD26660.1 - 1.4e-08 34.4 7.4 2.3e-06 27.3 0.4 2.8 2 1 1 3 3 3 2 Leucine rich repeat SOCS_box PF07525.16 PVD26660.1 - 0.048 14.0 0.1 0.048 14.0 0.1 3.0 3 1 0 3 3 3 0 SOCS box LRR_1 PF00560.33 PVD26660.1 - 0.068 13.8 6.3 5.6 7.9 0.2 5.4 4 2 1 5 5 5 0 Leucine Rich Repeat BIRC6 PF12356.8 PVD26661.1 - 2e-39 134.8 0.8 2.6e-38 131.2 0.1 2.9 2 1 0 2 2 2 1 Baculoviral IAP repeat-containing protein 6 UQ_con PF00179.26 PVD26661.1 - 2.6e-30 104.9 0.1 8.1e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PVD26661.1 - 7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PVD26661.1 - 0.026 14.8 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 RWD domain BIR PF00653.21 PVD26662.1 - 1.3e-20 73.8 3.0 3.8e-20 72.3 3.0 1.9 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain WD40 PF00400.32 PVD26662.1 - 0.031 15.2 0.3 0.27 12.2 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26662.1 - 0.092 13.1 0.1 80 3.6 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ubiquitin_2 PF14560.6 PVD26663.1 - 2.6e-28 98.3 0.1 6.5e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 PVD26663.1 - 2.3e-14 53.1 1.0 3.9e-14 52.4 1.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain CA_like PF10563.9 PVD26663.1 - 0.035 14.0 0.8 0.061 13.2 0.8 1.4 1 0 0 1 1 1 0 Putative carbonic anhydrase Somatomedin_B PF01033.17 PVD26664.1 - 0.25 11.8 18.4 1 9.8 18.4 2.1 1 0 0 1 1 1 0 Somatomedin B domain DUF3525 PF12039.8 PVD26667.1 - 0.046 12.4 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) F-box-like PF12937.7 PVD26670.1 - 2.2e-07 30.7 0.6 5e-07 29.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD26670.1 - 0.00014 21.6 0.6 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain Asparaginase_2 PF01112.18 PVD26671.1 - 1.1e-09 37.8 0.1 1.1e-09 37.7 0.1 1.0 1 0 0 1 1 1 1 Asparaginase DUF834 PF05754.14 PVD26671.1 - 0.021 14.9 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Asparaginase_2 PF01112.18 PVD26672.1 - 1.5e-62 211.4 22.7 8e-34 117.0 11.8 2.5 1 1 1 2 2 2 2 Asparaginase G_glu_transpept PF01019.21 PVD26672.1 - 0.033 13.0 0.2 0.033 13.0 0.2 1.6 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase UBX PF00789.20 PVD26673.1 - 1.2e-23 83.1 0.1 2.3e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 PVD26673.1 - 6.2e-09 35.6 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Utp11 PF03998.13 PVD26673.1 - 0.0083 16.1 18.4 0.011 15.7 18.4 1.2 1 0 0 1 1 1 1 Utp11 protein zf-C2H2_2 PF12756.7 PVD26673.1 - 2.9 8.3 7.2 0.7 10.3 2.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 PVD26674.1 - 8.6e-48 163.0 0.0 1.8e-47 161.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 PVD26674.1 - 1.9e-32 110.9 25.9 5.5e-17 61.4 6.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 PVD26674.1 - 1.9e-22 79.8 0.0 1.1e-21 77.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 PVD26674.1 - 1.1e-12 48.1 0.1 2.3e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 PVD26674.1 - 6.1e-10 39.6 1.7 1.9e-09 38.1 0.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C1_2 PF03107.16 PVD26674.1 - 0.0044 17.3 17.5 0.2 12.0 4.4 2.6 2 0 0 2 2 2 2 C1 domain Zf_RING PF16744.5 PVD26674.1 - 0.0054 16.8 13.5 0.18 12.0 5.1 2.6 2 0 0 2 2 2 2 KIAA1045 RING finger zf-RING_9 PF13901.6 PVD26674.1 - 0.056 13.4 17.0 0.47 10.4 3.3 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 PVD26674.1 - 0.78 9.9 10.2 2.2 8.4 0.7 2.7 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 PVD26674.1 - 4.9 7.1 22.7 3.2 7.7 5.9 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 PVD26674.1 - 5.5 7.2 15.4 1.9 8.7 3.1 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger Abhydrolase_1 PF00561.20 PVD26675.1 - 2.5e-29 102.7 0.0 7.1e-29 101.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD26675.1 - 8.6e-21 75.6 0.0 1.1e-20 75.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD26675.1 - 8e-11 41.7 0.0 1.9e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PVD26675.1 - 2.9e-05 22.9 0.0 0.00011 21.0 0.0 1.7 1 1 0 1 1 1 1 Ndr family Glyco_transf_7C PF02709.14 PVD26675.1 - 0.075 12.7 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase DUF3663 PF12404.8 PVD26675.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase Abhydrolase_1 PF00561.20 PVD26676.1 - 2.5e-22 79.8 0.1 4.7e-22 78.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD26676.1 - 2.8e-14 54.3 0.0 3.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD26676.1 - 7.2e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PVD26676.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 PVD26676.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein BRE PF06113.12 PVD26678.1 - 4.2e-85 285.4 0.0 4.8e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Xpo1 PF08389.12 PVD26679.1 - 1.1e-17 64.5 4.5 3.9e-17 62.7 0.1 3.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 PVD26679.1 - 9.2e-08 31.9 0.0 3.9e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2721 PF11026.8 PVD26679.1 - 0.083 12.8 0.1 2.4 8.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) zf-C2H2_jaz PF12171.8 PVD26680.1 - 0.0019 18.4 0.1 0.0054 17.0 0.1 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD26680.1 - 0.0036 18.0 0.5 0.018 15.8 0.5 2.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD26680.1 - 0.0039 17.6 0.5 0.015 15.7 0.5 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type Dor1 PF04124.12 PVD26680.1 - 0.021 13.5 0.2 0.29 9.8 0.0 2.3 2 1 0 2 2 2 0 Dor1-like family DUF3402 PF11882.8 PVD26680.1 - 0.078 12.1 6.4 0.16 11.0 6.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3402) Ion_trans PF00520.31 PVD26681.1 - 3.2e-227 750.3 107.8 1.7e-68 230.5 21.6 5.1 4 1 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 PVD26681.1 - 9.7e-10 39.1 17.7 1.3e-09 38.7 1.8 4.3 3 1 0 3 3 3 1 Sodium ion transport-associated Na_trans_cytopl PF11933.8 PVD26681.1 - 8.4e-08 32.3 11.5 1.3e-05 25.1 11.5 2.7 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel PKD_channel PF08016.12 PVD26681.1 - 3.5e-05 22.7 87.4 0.017 13.8 14.5 8.4 5 3 1 6 6 6 4 Polycystin cation channel GPHH PF16905.5 PVD26681.1 - 0.018 14.8 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Phage_Gp23 PF10669.9 PVD26681.1 - 0.39 11.1 3.7 20 5.6 0.0 3.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) OAD_gamma PF04277.13 PVD26681.1 - 1.2 9.8 0.0 1.2 9.8 0.0 5.3 6 0 0 6 6 6 0 Oxaloacetate decarboxylase, gamma chain Conotoxin PF02950.17 PVD26681.1 - 9.4 7.3 7.6 4.2 8.5 0.0 3.8 3 0 0 3 3 3 0 Conotoxin OATP PF03137.20 PVD26682.1 - 3.8e-102 342.3 12.5 2.3e-86 290.3 1.4 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Med6 PF04934.14 PVD26682.1 - 3.4e-43 146.6 0.4 5.3e-43 146.0 0.4 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component MFS_1 PF07690.16 PVD26682.1 - 6.4e-14 51.6 24.9 3.4e-11 42.7 10.6 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD26682.1 - 0.95 9.6 11.2 0.083 13.0 6.1 1.9 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain WD40 PF00400.32 PVD26683.1 - 2.8e-13 50.1 8.3 0.0017 19.1 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 PVD26683.1 - 0.0011 18.9 0.1 6.4 6.6 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PVD26683.1 - 0.0073 16.6 0.0 2.7 8.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain XRN_M PF17846.1 PVD26684.1 - 1.5e-163 544.9 0.1 2e-163 544.5 0.1 1.1 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 PVD26684.1 - 4.5e-93 311.1 0.2 1.9e-92 309.1 0.0 2.1 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_4 PF14392.6 PVD26684.1 - 0.072 12.8 0.2 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Homeodomain PF00046.29 PVD26686.1 - 5e-20 71.1 5.6 7.5e-20 70.5 5.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD26686.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3510 PF12022.8 PVD26689.1 - 5e-37 127.1 0.4 1.3e-36 125.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 PVD26689.1 - 4.5e-35 120.6 1.7 3.4e-34 117.8 0.1 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 PVD26689.1 - 0.039 14.5 0.8 0.64 10.6 0.1 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Vps51 PF08700.11 PVD26689.1 - 0.055 13.6 0.3 0.6 10.2 0.0 2.9 2 1 0 2 2 2 0 Vps51/Vps67 DUF4795 PF16043.5 PVD26689.1 - 0.09 12.4 3.1 0.17 11.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 PVD26689.1 - 0.68 10.0 4.2 1.3 9.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_UBOX PF13445.6 PVD26690.1 - 1.5e-06 28.1 4.0 1.5e-06 28.1 4.0 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD26690.1 - 1.7e-06 28.1 1.5 1.7e-06 28.1 1.5 4.6 4 2 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD26690.1 - 1.8e-06 27.7 2.4 1.8e-06 27.7 2.4 4.1 4 2 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD26690.1 - 4.1e-06 26.5 3.1 4.1e-06 26.5 3.1 4.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD26690.1 - 5.7e-06 26.4 4.1 5.7e-06 26.4 4.1 4.2 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD26690.1 - 5.9e-06 26.1 2.0 5.9e-06 26.1 2.0 4.8 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD26690.1 - 0.0015 18.8 1.8 0.0015 18.8 1.8 4.2 4 1 0 4 4 4 1 Ring finger domain CEBP_ZZ PF16366.5 PVD26690.1 - 0.0032 17.7 5.5 0.0032 17.7 5.5 3.2 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Prok-RING_4 PF14447.6 PVD26690.1 - 0.008 16.0 2.8 0.008 16.0 2.8 4.2 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 DUF4637 PF15470.6 PVD26690.1 - 0.0084 15.9 1.7 0.016 14.9 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) FokI_C PF02980.16 PVD26690.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain fn3 PF00041.21 PVD26691.1 - 1.8e-08 34.6 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.6 PVD26691.1 - 0.00016 21.2 0.0 0.00054 19.5 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 PVD26692.1 - 1.3e-07 31.7 0.0 1.5e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 SPRY domain 7kD_DNA_binding PF02294.18 PVD26694.1 - 0.47 10.5 2.7 0.31 11.1 0.9 1.6 1 1 1 2 2 2 0 7kD DNA-binding domain PCMT PF01135.19 PVD26695.1 - 6.6e-80 267.8 0.1 7.8e-80 267.6 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PVD26695.1 - 7.3e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD26695.1 - 1.3e-05 25.8 0.0 2.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD26695.1 - 2.7e-05 23.6 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 PVD26695.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD26695.1 - 0.00035 21.2 0.1 0.0011 19.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD26695.1 - 0.00038 20.0 0.1 0.00094 18.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PVD26695.1 - 0.0029 17.1 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 PVD26695.1 - 0.0048 16.8 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD26695.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 PVD26695.1 - 0.22 11.0 0.4 0.5 9.9 0.3 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 MANEC PF07502.14 PVD26696.1 - 6.7e-14 51.9 6.9 6.7e-14 51.9 6.9 2.3 2 0 0 2 2 2 1 MANEC domain Ldl_recept_a PF00057.18 PVD26696.1 - 1.8e-06 28.0 4.7 1.8e-06 28.0 4.7 3.1 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A EB PF01683.18 PVD26696.1 - 4.7e-06 26.8 3.7 4.7e-06 26.8 3.7 3.1 3 0 0 3 3 3 1 EB module DUF1180 PF06679.12 PVD26696.1 - 1.4 9.3 4.9 0.58 10.6 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) PP1_inhibitor PF05361.12 PVD26697.1 - 2.3e-09 37.4 0.2 4.2e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor ECH_1 PF00378.20 PVD26698.1 - 3.5e-92 308.2 0.4 4.1e-92 308.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD26698.1 - 4.1e-38 131.7 1.5 1.6e-33 116.6 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PVD26698.1 - 0.01 15.8 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 DUF3624 PF12292.8 PVD26699.1 - 0.13 12.6 2.1 0.15 12.5 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) Sushi PF00084.20 PVD26702.1 - 3e-38 130.2 36.0 3.7e-10 40.3 1.4 5.5 5 0 0 5 5 5 5 Sushi repeat (SCR repeat) HRM PF02793.22 PVD26702.1 - 0.019 15.2 13.7 0.16 12.3 0.1 4.6 4 0 0 4 4 4 0 Hormone receptor domain EphA2_TM PF14575.6 PVD26702.1 - 0.033 15.1 0.1 0.84 10.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 PVD26702.1 - 0.037 13.9 0.6 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TMEM51 PF15345.6 PVD26702.1 - 0.049 13.5 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 cEGF PF12662.7 PVD26702.1 - 0.24 11.3 9.9 1.3 9.1 1.0 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like Zip PF02535.22 PVD26703.1 - 3.6e-36 125.1 21.4 7.6e-27 94.4 9.3 3.1 1 1 1 2 2 2 2 ZIP Zinc transporter Acyl_transf_3 PF01757.22 PVD26703.1 - 0.0054 15.8 0.9 0.0054 15.8 0.9 1.6 2 0 0 2 2 2 1 Acyltransferase family Branch PF02485.21 PVD26707.1 - 3.6e-32 111.8 0.1 5.7e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD26708.1 - 5.2e-09 36.0 0.1 9e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Nup84_Nup100 PF04121.13 PVD26708.1 - 0.085 10.9 0.0 0.099 10.7 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 MFS_1 PF07690.16 PVD26709.1 - 1.9e-20 73.1 18.1 2.6e-20 72.7 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 PVD26709.1 - 0.036 13.6 0.4 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CsoS2_M PF12288.8 PVD26710.1 - 0.032 13.7 3.8 0.049 13.0 3.8 1.3 1 1 0 1 1 1 0 Carboxysome shell peptide mid-region Bul1_C PF04426.12 PVD26710.1 - 1.5 8.1 10.5 6.6 6.1 10.5 1.8 1 1 0 1 1 1 0 Bul1 C terminus SERTA PF06031.13 PVD26711.1 - 3.6e-13 48.9 0.7 6e-13 48.2 0.7 1.4 1 0 0 1 1 1 1 SERTA motif Menin PF05053.13 PVD26712.1 - 1.6e-214 714.2 8.7 1.5e-197 658.1 0.3 2.0 1 1 1 2 2 2 2 Menin TPR_2 PF07719.17 PVD26712.1 - 0.13 12.4 0.5 0.46 10.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt5_N PF11942.8 PVD26712.1 - 0.54 11.3 13.5 1.4 9.9 13.5 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 PVD26712.1 - 1.8 6.8 10.5 2.7 6.2 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CLPTM1 PF05602.12 PVD26713.1 - 1.5e-149 498.7 8.2 1.8e-149 498.4 8.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 PVD26713.1 - 0.052 13.3 5.1 0.58 10.0 0.2 3.0 3 0 0 3 3 3 0 PQ loop repeat Helicase_C_4 PF13871.6 PVD26714.1 - 6.7e-112 373.6 0.2 1.1e-111 373.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue AAA_34 PF13872.6 PVD26714.1 - 2.3e-111 371.5 0.0 3.9e-111 370.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 UBZ_FAAP20 PF15750.5 PVD26714.1 - 0.0032 17.4 0.1 0.0074 16.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-binding zinc-finger ResIII PF04851.15 PVD26714.1 - 0.091 12.8 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HLH PF00010.26 PVD26715.1 - 1.9e-15 56.5 1.9 3.9e-15 55.5 1.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIF_alpha PF05793.12 PVD26715.1 - 0.074 11.6 15.9 0.019 13.6 12.1 1.7 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Luteo_Vpg PF01659.16 PVD26715.1 - 0.19 12.1 4.7 0.082 13.3 2.1 1.7 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein Macoilin PF09726.9 PVD26715.1 - 4.6 5.7 7.6 5.7 5.4 7.6 1.0 1 0 0 1 1 1 0 Macoilin family HLH PF00010.26 PVD26717.1 - 3.3e-15 55.8 0.1 5.5e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.9 PVD26718.1 - 2.5 6.6 21.6 2.9 6.3 21.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF4508 PF14969.6 PVD26719.1 - 7.2e-32 109.5 4.0 9.4e-32 109.1 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Sec3_C_2 PF15278.6 PVD26719.1 - 0.039 14.3 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DUF2158 PF09926.9 PVD26719.1 - 0.25 11.1 1.4 1.1 9.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) UTP25 PF06862.12 PVD26720.1 - 8.2e-173 575.5 6.9 1.1e-172 575.1 6.9 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 PVD26720.1 - 0.0017 18.1 0.0 0.16 11.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 PVD26721.1 - 1.9e-14 53.2 0.1 3.1e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD26721.1 - 0.00027 20.5 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) fn3 PF00041.21 PVD26722.1 - 1.3e-12 47.9 6.9 2.4e-05 24.6 0.1 4.1 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD26722.1 - 4.7e-06 27.1 5.8 0.047 14.2 0.1 3.5 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 PVD26722.1 - 0.00045 20.5 0.2 3.1 8.3 0.0 3.4 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) DUF2162 PF09930.9 PVD26722.1 - 0.096 12.1 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF4124 PF13511.6 PVD26722.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) SNAP PF14938.6 PVD26723.1 - 1.2e-109 366.1 21.4 1.4e-109 365.9 21.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 PVD26723.1 - 4.3e-08 33.3 13.3 9.8e-06 25.8 2.1 3.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26723.1 - 6.7e-05 22.7 16.7 0.029 14.5 0.1 5.5 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD26723.1 - 6.9e-05 22.6 9.2 0.1 12.7 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat NSF PF02071.20 PVD26723.1 - 0.00018 21.6 34.7 1.7 9.8 2.6 8.4 8 0 0 8 8 8 3 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 PVD26723.1 - 0.00024 21.0 14.2 0.33 11.3 0.1 5.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD26723.1 - 0.00037 20.9 9.0 0.049 14.3 0.0 4.5 4 1 1 5 5 4 1 Tetratricopeptide repeat Sel1 PF08238.12 PVD26723.1 - 0.0024 18.5 3.4 31 5.4 0.0 4.6 4 0 0 4 4 4 0 Sel1 repeat Spatacsin_C PF14649.6 PVD26723.1 - 0.0069 15.5 10.0 0.13 11.4 9.2 2.6 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_11 PF13414.6 PVD26723.1 - 0.014 15.1 16.9 0.15 11.7 0.0 4.6 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 PVD26723.1 - 0.014 15.2 8.2 3.2 7.8 0.1 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF2076 PF09849.9 PVD26723.1 - 0.016 15.3 1.1 0.028 14.5 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_1 PF00515.28 PVD26723.1 - 0.08 12.8 20.3 0.31 11.0 0.2 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD26723.1 - 0.13 13.2 5.4 14 6.8 0.0 4.2 4 1 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD26723.1 - 0.2 11.9 9.4 0.39 11.0 2.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PVD26723.1 - 1.2 9.7 9.5 1.9 9.0 1.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD26723.1 - 5.6 7.7 7.6 4.8 7.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Spc7 PF08317.11 PVD26724.1 - 0.00024 20.1 18.4 0.00035 19.6 18.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS38 PF17649.1 PVD26724.1 - 0.0074 15.2 6.5 0.0093 14.9 6.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Tup_N PF08581.10 PVD26724.1 - 0.0078 16.5 3.6 0.0078 16.5 3.6 3.1 2 1 0 2 2 2 1 Tup N-terminal CheZ PF04344.13 PVD26724.1 - 0.0089 16.0 10.0 0.015 15.3 10.0 1.3 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ KIP1 PF07765.12 PVD26724.1 - 0.023 14.8 6.2 0.023 14.8 6.2 2.6 1 1 1 2 2 2 0 KIP1-like protein YojJ PF10372.9 PVD26724.1 - 0.031 14.4 9.6 0.32 11.1 1.3 2.6 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Elf4 PF07011.11 PVD26724.1 - 0.042 13.8 0.3 0.091 12.7 0.3 1.6 1 0 0 1 1 1 0 Early Flowering 4 domain WDCP PF15390.6 PVD26724.1 - 0.047 12.1 5.8 0.054 11.9 5.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Lipase_GDSL PF00657.22 PVD26724.1 - 0.075 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Exonuc_VII_L PF02601.15 PVD26724.1 - 0.12 11.9 8.1 0.17 11.4 8.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2937 PF11157.8 PVD26724.1 - 0.17 11.6 0.8 1.3 8.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Spectrin PF00435.21 PVD26724.1 - 0.18 12.3 15.6 0.59 10.7 8.5 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF3138 PF11336.8 PVD26724.1 - 0.23 10.0 0.3 0.3 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PIN_8 PF18476.1 PVD26724.1 - 0.31 10.9 11.0 0.45 10.3 11.0 1.1 1 0 0 1 1 1 0 PIN like domain Fib_alpha PF08702.10 PVD26724.1 - 0.54 10.4 13.6 1.8 8.7 4.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 PVD26724.1 - 0.75 9.7 9.8 1.1 9.1 7.2 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3584 PF12128.8 PVD26724.1 - 0.76 7.2 18.6 0.97 6.9 18.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.7 PVD26724.1 - 1 9.5 28.6 1.9 8.6 26.0 2.1 1 1 0 1 1 1 0 Tropomyosin like V_ATPase_I PF01496.19 PVD26724.1 - 1.2 7.0 9.6 1.6 6.6 9.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 PVD26724.1 - 1.3 8.8 9.2 1.8 8.3 9.2 1.3 1 0 0 1 1 1 0 AAA domain DHHA1 PF02272.19 PVD26724.1 - 1.6 9.1 5.3 1.6 9.2 3.8 1.8 1 1 0 1 1 1 0 DHHA1 domain BLOC1_2 PF10046.9 PVD26724.1 - 1.7 9.0 15.0 0.4 11.0 4.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2259 PF10016.9 PVD26724.1 - 2.6 8.0 4.6 4.2 7.3 4.6 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Nup88 PF10168.9 PVD26724.1 - 3.4 5.4 15.2 4.6 4.9 15.2 1.1 1 0 0 1 1 1 0 Nuclear pore component CENP-F_leu_zip PF10473.9 PVD26724.1 - 3.4 7.7 30.8 92 3.0 21.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 PVD26724.1 - 4.3 6.1 9.3 5.3 5.8 9.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.6 PVD26724.1 - 4.4 5.8 13.9 5.6 5.5 13.9 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 PVD26724.1 - 4.4 6.6 24.7 16 4.7 24.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 PVD26724.1 - 5.2 7.1 13.0 14 5.8 7.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 PVD26724.1 - 5.3 7.1 6.8 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Sec20 PF03908.13 PVD26724.1 - 5.9 6.9 6.4 12 5.8 3.4 2.3 1 1 2 3 3 3 0 Sec20 TPR_MLP1_2 PF07926.12 PVD26724.1 - 6 7.0 24.3 6.6 6.8 4.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HSP70 PF00012.20 PVD26724.1 - 6.1 4.9 14.8 8.5 4.4 14.8 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF948 PF06103.11 PVD26724.1 - 6.2 7.2 5.7 37 4.7 5.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ARD PF03079.14 PVD26724.1 - 6.4 6.9 10.9 6.2 7.0 9.7 1.6 1 1 1 2 2 2 0 ARD/ARD' family Fmp27_WPPW PF10359.9 PVD26724.1 - 9.6 4.9 16.6 19 4.0 16.6 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_C2 PF00648.21 PVD26725.1 - 0.05 12.6 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease RAB3GAP2_C PF14656.6 PVD26727.1 - 5.4e-167 556.7 7.0 9.5e-167 555.8 7.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 PVD26727.1 - 2.1e-145 485.1 0.0 2.8e-145 484.7 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_C2 PF00648.21 PVD26727.1 - 1.2e-127 425.0 0.0 2.2e-127 424.2 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD26727.1 - 4.3e-49 166.4 0.0 8.1e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 PVD26727.1 - 1.3e-08 33.8 0.2 0.016 14.7 0.0 4.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD26727.1 - 2.1e-07 30.3 0.9 0.01 15.7 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 PVD26727.1 - 5.1e-06 26.2 2.4 1.7e-05 24.6 0.3 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 PVD26727.1 - 0.00015 22.1 1.0 0.019 15.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Fer4_7 PF12838.7 PVD26727.1 - 1.1 10.0 2.9 33 5.2 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 PVD26727.1 - 2.4 9.3 5.8 41 5.4 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain ERO1 PF04137.15 PVD26729.1 - 1.3e-115 386.4 1.3 1.8e-115 386.0 1.3 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Methyltransf_28 PF02636.17 PVD26730.1 - 6.9e-56 189.8 0.0 9e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase B9-C2 PF07162.11 PVD26731.1 - 1.8e-56 190.9 0.1 3.1e-56 190.2 0.1 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein RRM_1 PF00076.22 PVD26731.1 - 2e-22 78.8 0.2 1.6e-10 40.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD26731.1 - 1.6e-06 28.2 0.0 0.098 12.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD26731.1 - 3.1e-05 23.9 0.1 0.35 10.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 PVD26731.1 - 0.014 15.2 0.7 6.2 6.6 0.1 3.0 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 PVD26731.1 - 0.026 14.4 0.1 0.65 9.9 0.1 2.6 2 1 0 2 2 2 0 Occluded RNA-recognition motif SQHop_cyclase_C PF13243.6 PVD26731.1 - 0.17 10.9 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain FtsH_ext PF06480.15 PVD26733.1 - 1.1 9.6 3.3 0.72 10.2 0.1 2.3 3 0 0 3 3 3 0 FtsH Extracellular bZIP_1 PF00170.21 PVD26734.1 - 3.7e-06 26.9 11.6 7.4e-06 26.0 11.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD26734.1 - 1.8e-05 25.1 10.4 4.4e-05 23.9 10.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PVD26734.1 - 2.6e-05 24.2 13.5 6.5e-05 22.9 13.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Syntaxin-18_N PF10496.9 PVD26734.1 - 0.052 13.8 1.1 0.12 12.7 1.1 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF2514 PF10721.9 PVD26734.1 - 0.18 11.8 3.9 0.43 10.6 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) bZIP_2 PF07716.15 PVD26735.1 - 4.4e-09 36.3 17.5 8.1e-09 35.4 17.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD26735.1 - 1.7e-08 34.4 15.6 2.9e-08 33.7 15.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD26735.1 - 1.2e-05 25.8 10.3 2.9e-05 24.5 10.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 PVD26735.1 - 0.013 15.7 0.0 0.083 13.1 0.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 PVD26735.1 - 0.2 11.7 7.9 0.36 10.9 7.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 PVD26735.1 - 0.25 10.6 1.8 0.39 10.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.17 PVD26737.1 - 2.5e-06 27.9 14.1 4.4e-06 27.1 14.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PVD26737.1 - 1.5e-05 25.0 24.3 9.7e-05 22.4 24.3 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD26737.1 - 1.6e-05 24.9 19.6 2.7e-05 24.2 19.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_2 PF02230.16 PVD26740.1 - 3.4e-18 66.2 0.0 3.8e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PVD26740.1 - 1.1e-05 25.0 0.3 0.0093 15.5 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PVD26740.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD26740.1 - 0.00012 21.4 0.6 0.04 13.2 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 PVD26740.1 - 0.00014 21.8 0.1 0.0089 15.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 PVD26740.1 - 0.00017 21.2 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.20 PVD26740.1 - 0.0011 19.2 0.2 0.0021 18.2 0.1 1.5 1 1 1 2 2 2 1 Thioesterase domain Esterase PF00756.20 PVD26740.1 - 0.0055 16.4 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.9 PVD26740.1 - 0.0091 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 PVD26740.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 PVD26740.1 - 0.026 15.1 1.7 0.03 14.9 0.6 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Esterase_phd PF10503.9 PVD26740.1 - 0.061 12.8 0.2 0.21 11.0 0.2 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 PVD26740.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Forkhead PF00250.18 PVD26742.1 - 3.4e-36 123.4 0.1 6.9e-36 122.4 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Diphthami_syn_2 PF01902.17 PVD26743.1 - 1.3e-35 122.9 0.0 2.4e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 PVD26743.1 - 9e-20 70.9 0.0 2.4e-08 34.0 0.0 3.3 3 0 0 3 3 3 2 Endoribonuclease L-PSP Golgin_A5 PF09787.9 PVD26744.1 - 2.8e-116 388.3 26.3 2.8e-116 388.3 26.3 3.2 1 1 2 3 3 3 1 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 PVD26744.1 - 0.0018 18.8 13.7 0.0018 18.8 13.7 5.3 2 1 4 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 PVD26744.1 - 0.0052 16.8 17.4 0.0052 16.8 17.4 4.9 2 2 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Caskin-tail PF16632.5 PVD26744.1 - 0.011 16.1 2.3 0.011 16.1 2.3 3.6 3 2 1 4 4 4 0 C-terminal region of Caskin PKcGMP_CC PF16808.5 PVD26744.1 - 0.32 10.9 0.1 0.32 10.9 0.1 5.0 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 PVD26744.1 - 0.84 7.1 59.7 1.3 6.5 59.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Apolipoprotein PF01442.18 PVD26745.1 - 0.0024 17.8 0.1 0.005 16.7 0.1 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain RVT_1 PF00078.27 PVD26746.1 - 1.5e-31 109.7 0.0 2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD26747.1 - 1.6e-07 31.1 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Copper-fist PF00649.18 PVD26747.1 - 0.037 13.5 2.7 0.099 12.2 2.7 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC PF00098.23 PVD26747.1 - 0.038 14.1 1.9 0.087 12.9 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 PVD26748.1 - 4.1e-05 23.8 0.0 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein SCAN PF02023.17 PVD26748.1 - 0.00017 21.3 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 SCAN domain PNMA PF14893.6 PVD26748.1 - 0.00044 19.8 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 PNMA Lectin_C PF00059.21 PVD26749.1 - 0.0065 17.2 0.7 0.0077 16.9 0.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain VID27_N PF17748.1 PVD26749.1 - 0.034 14.0 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 VID27 N-terminal region DUF4611 PF15387.6 PVD26750.1 - 7.2e-06 26.1 4.1 9.1e-06 25.8 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.10 PVD26750.1 - 0.00045 20.3 1.6 0.0011 19.1 1.6 1.7 1 1 0 1 1 1 1 Gon7 family Sod_Cu PF00080.20 PVD26752.1 - 1.4e-18 67.5 0.6 2e-18 67.0 0.6 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 PVD26752.1 - 2.8e-10 40.5 0.1 6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Fn3-like PF14310.6 PVD26752.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III-like domain TPR_12 PF13424.6 PVD26753.1 - 4.1e-33 113.5 12.5 9.8e-18 64.2 0.2 5.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD26753.1 - 6e-33 111.8 10.9 1.4e-07 31.2 0.0 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD26753.1 - 3.5e-24 83.6 10.1 2.2e-05 24.1 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD26753.1 - 1.2e-20 71.9 9.6 0.00068 19.6 0.0 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD26753.1 - 1.8e-19 68.3 11.0 0.00048 20.1 0.1 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat DUF4062 PF13271.6 PVD26753.1 - 2.2e-16 60.0 0.0 1.2e-15 57.7 0.0 2.3 2 0 0 2 2 1 1 Domain of unknown function (DUF4062) TPR_7 PF13176.6 PVD26753.1 - 5.2e-16 57.4 13.5 0.0075 16.2 0.0 7.6 8 0 0 8 8 6 4 Tetratricopeptide repeat NACHT PF05729.12 PVD26753.1 - 2.2e-12 47.2 0.2 8.4e-12 45.3 0.0 2.1 2 0 0 2 2 1 1 NACHT domain TPR_17 PF13431.6 PVD26753.1 - 2.3e-10 40.1 0.8 0.06 13.8 0.1 6.6 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD26753.1 - 1e-09 38.3 8.4 9.5e-05 21.9 4.4 3.4 3 1 1 4 4 4 2 MalT-like TPR region AAA_16 PF13191.6 PVD26753.1 - 3e-09 37.5 0.9 2.6e-08 34.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_14 PF13428.6 PVD26753.1 - 3.5e-08 33.6 12.5 4 8.5 0.1 9.7 8 2 2 10 10 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD26753.1 - 4.3e-08 33.6 17.2 0.14 12.6 0.0 7.5 8 1 1 9 9 6 3 Tetratricopeptide repeat AAA_22 PF13401.6 PVD26753.1 - 4.7e-07 30.1 0.3 1.2e-05 25.6 0.0 3.2 2 1 0 3 3 2 1 AAA domain TPR_16 PF13432.6 PVD26753.1 - 6.7e-07 29.8 14.9 0.016 15.9 0.0 5.8 6 1 1 7 7 5 3 Tetratricopeptide repeat ATPase_2 PF01637.18 PVD26753.1 - 7.4e-06 26.0 0.0 2.6e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 PVD26753.1 - 0.00021 21.2 0.0 0.00063 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 PVD26753.1 - 0.0057 15.9 0.0 1.7 7.8 0.1 2.4 2 0 0 2 2 2 1 KAP family P-loop domain cobW PF02492.19 PVD26753.1 - 0.038 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TPR_6 PF13174.6 PVD26753.1 - 0.047 14.3 14.2 25 5.8 0.0 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF2075 PF09848.9 PVD26753.1 - 0.049 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_4 PF07721.14 PVD26753.1 - 0.05 14.3 12.5 5.2 8.0 0.2 6.0 6 0 0 6 6 4 0 Tetratricopeptide repeat AAA PF00004.29 PVD26753.1 - 0.052 14.0 0.1 0.92 9.9 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SNAP PF14938.6 PVD26753.1 - 0.064 12.7 1.2 0.42 10.0 0.1 2.9 2 2 2 4 4 4 0 Soluble NSF attachment protein, SNAP AAA_7 PF12775.7 PVD26753.1 - 0.082 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 PVD26753.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GvpD PF07088.11 PVD26753.1 - 0.17 10.4 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein Mt_ATP-synt_B PF05405.14 PVD26753.1 - 1.2 8.8 4.9 0.81 9.3 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PcF PF09461.10 PVD26753.1 - 6.7 7.2 6.4 32 5.0 1.1 3.0 2 0 0 2 2 2 0 Phytotoxin PcF protein Glycos_transf_2 PF00535.26 PVD26754.1 - 4.4e-29 101.5 0.0 6.5e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 PVD26754.1 - 2e-06 27.3 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PVD26754.1 - 1.7e-05 24.9 0.0 5.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD26754.1 - 0.0039 16.7 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 PVD26755.1 - 3.6e-07 30.5 0.4 4.1e-07 30.3 0.4 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 PVD26755.1 - 0.033 14.9 0.0 0.045 14.5 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like VitD-bind_III PF09164.10 PVD26757.1 - 0.0016 18.4 3.4 6.4 6.8 0.1 3.9 2 2 3 5 5 5 3 Vitamin D binding protein, domain III Yae1_N PF09811.9 PVD26757.1 - 0.0063 16.2 10.6 45 3.9 0.1 5.8 1 1 10 11 11 11 5 Essential protein Yae1, N terminal RR_TM4-6 PF06459.12 PVD26758.1 - 0.085 12.7 10.5 0.1 12.4 10.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TP53IP5 PF15331.6 PVD26758.1 - 0.22 11.6 12.7 0.32 11.1 12.7 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 PVD26758.1 - 0.29 9.8 17.3 0.35 9.6 17.3 1.1 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 PVD26758.1 - 0.46 10.5 9.3 0.5 10.4 9.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MDM10 PF12519.8 PVD26758.1 - 3.3 6.5 13.0 4.2 6.1 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Neur_chan_memb PF02932.16 PVD26758.1 - 4.7 7.2 11.4 6.5 6.7 11.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 PVD26758.1 - 5 5.8 13.9 5.6 5.6 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 PVD26758.1 - 5.1 5.1 12.3 5.3 5.0 12.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCM_bind PF09739.9 PVD26758.1 - 7.6 4.8 17.8 9.6 4.5 17.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4569 PF15133.6 PVD26758.1 - 8.9 5.9 9.2 9.8 5.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SIR2 PF02146.17 PVD26760.1 - 5.1e-57 192.6 0.0 7.6e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family EF-hand_1 PF00036.32 PVD26761.1 - 3e-37 123.4 9.3 1.2e-09 37.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD26761.1 - 2.2e-32 111.3 1.4 5.8e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD26761.1 - 1.9e-28 98.0 12.3 7.7e-13 48.1 0.1 4.6 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD26761.1 - 2.4e-26 89.4 5.3 3.1e-09 36.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD26761.1 - 1.3e-23 81.4 7.3 1.7e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PVD26761.1 - 1.3e-12 47.9 0.1 7.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PVD26761.1 - 3.7e-06 26.8 0.1 0.044 13.7 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PVD26761.1 - 1.1e-05 25.7 0.0 0.068 13.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PVD26761.1 - 5.9e-05 23.0 0.0 0.1 12.7 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 PVD26761.1 - 0.00028 21.7 0.0 0.054 14.4 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 PVD26761.1 - 0.00066 19.7 0.2 0.0028 17.7 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 PVD26761.1 - 0.00082 19.8 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 PVD26761.1 - 0.0042 17.4 0.2 1.3 9.4 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 Dockerin_1 PF00404.18 PVD26761.1 - 0.0046 17.1 4.5 0.37 11.0 0.3 3.2 1 1 2 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 PVD26761.1 - 0.013 15.4 0.4 0.84 9.5 0.2 3.1 1 1 0 1 1 1 0 Caleosin related protein DUF1103 PF06513.11 PVD26761.1 - 0.017 14.7 1.1 0.024 14.3 1.1 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 PVD26761.1 - 0.018 15.8 0.2 6.4 7.6 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) TerB PF05099.13 PVD26761.1 - 0.021 14.8 0.4 1.4 8.9 0.1 3.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Poly_export PF02563.16 PVD26761.1 - 0.1 12.8 0.0 2.5 8.4 0.0 2.7 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein dCache_2 PF08269.11 PVD26761.1 - 0.13 11.4 0.1 7.9 5.6 0.0 2.3 1 1 0 2 2 2 0 Cache domain MotA_activ PF09114.10 PVD26761.1 - 0.16 12.1 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Amdo_NSP PF12475.8 PVD26761.1 - 0.18 11.9 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Amdovirus non-structural protein EF-hand_1 PF00036.32 PVD26762.1 - 2e-21 73.9 1.8 2.5e-06 26.6 0.1 3.5 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD26762.1 - 9e-20 68.9 2.4 1.4e-05 24.6 0.2 3.9 3 2 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD26762.1 - 1.1e-18 65.8 5.6 8.8e-06 25.0 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD26762.1 - 7.7e-17 61.5 0.2 4.5e-10 39.8 1.3 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 PVD26762.1 - 1.1e-10 41.6 0.0 8.5e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD26762.1 - 2e-10 40.3 4.1 1.7e-05 24.5 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_14 PF17959.1 PVD26762.1 - 0.00043 20.6 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PVD26762.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 PVD26762.1 - 0.003 18.4 0.0 0.11 13.4 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain Toprim_2 PF13155.6 PVD26762.1 - 0.035 14.5 0.0 4.8 7.7 0.0 2.3 1 1 0 2 2 2 0 Toprim-like SPARC_Ca_bdg PF10591.9 PVD26762.1 - 0.13 12.6 0.0 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 PVD26762.1 - 0.14 12.0 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 EF hand Slx4 PF09494.10 PVD26762.1 - 0.17 11.9 0.0 1.7 8.7 0.0 2.3 1 1 1 2 2 2 0 Slx4 endonuclease DUF1456 PF07308.13 PVD26762.1 - 0.19 12.1 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 PVD26763.1 - 4.1e-14 51.0 0.5 2.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD26763.1 - 4.3e-12 46.3 0.2 7.7e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD26763.1 - 8.8e-12 44.7 0.3 1.1e-10 41.1 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD26763.1 - 3.5e-10 39.0 0.1 9.9e-08 31.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 PVD26763.1 - 3.7e-10 38.8 0.3 3.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.13 PVD26763.1 - 0.0027 17.7 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) TipE PF16972.5 PVD26763.1 - 0.013 14.7 0.8 0.015 14.5 0.8 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE EF-hand_9 PF14658.6 PVD26763.1 - 0.028 14.7 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_11 PF08976.11 PVD26763.1 - 0.066 14.1 0.1 0.15 12.9 0.1 1.7 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD26763.1 - 0.11 12.8 0.7 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 PVD26764.1 - 1.1e-11 43.4 0.6 2e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD26764.1 - 8.8e-10 37.7 0.3 9.5e-09 34.5 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PVD26764.1 - 4.6e-08 33.4 0.1 6.2e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD26764.1 - 4e-06 26.1 0.5 4.2e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PVD26764.1 - 2.1e-05 24.3 2.6 0.00027 20.7 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 PVD26764.1 - 0.00038 20.7 0.0 0.00051 20.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 PVD26764.1 - 0.054 13.8 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PVD26767.1 - 1.3e-25 89.6 1.2 3.3e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD26767.1 - 9.1e-25 84.3 5.4 8.3e-07 28.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PVD26767.1 - 9.5e-22 76.6 6.4 3.4e-09 36.4 0.3 4.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD26767.1 - 1.7e-18 64.9 3.8 9.9e-07 28.2 0.0 4.5 4 2 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 PVD26767.1 - 6.5e-09 34.9 4.0 0.0033 16.8 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 PVD26767.1 - 0.00019 21.7 0.1 0.028 14.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DUF3006 PF11213.8 PVD26767.1 - 0.01 16.0 6.4 8.9 6.6 0.5 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3006) EF-hand_4 PF12763.7 PVD26767.1 - 0.013 15.4 0.4 0.54 10.2 0.1 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 PVD26767.1 - 0.015 15.2 0.4 4.5 7.1 0.1 2.4 1 1 1 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 PVD26767.1 - 0.018 15.0 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein MotA_activ PF09114.10 PVD26767.1 - 0.02 15.0 0.1 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain EF-hand_11 PF08976.11 PVD26767.1 - 0.027 15.3 0.0 0.22 12.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain UPF0154 PF03672.13 PVD26767.1 - 0.042 13.9 0.0 10 6.3 0.0 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF3019 PF11456.8 PVD26767.1 - 0.11 13.0 1.4 0.42 11.1 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3019) GPHH PF16905.5 PVD26767.1 - 0.11 12.3 0.0 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_14 PF17959.1 PVD26767.1 - 0.13 12.6 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF2095 PF09868.9 PVD26767.1 - 0.51 10.3 5.5 0.11 12.5 0.6 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) Secretogranin_V PF05281.11 PVD26768.1 - 1.7e-38 132.5 1.3 2.6e-38 131.9 1.3 1.2 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) DDHD PF02862.17 PVD26769.1 - 1.3e-45 156.3 0.0 2.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 PVD26769.1 - 0.044 13.3 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ank_4 PF13637.6 PVD26770.1 - 2.2e-24 85.5 1.3 1.3e-16 60.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26770.1 - 5.3e-17 62.2 0.7 1.2e-16 61.0 0.8 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD26770.1 - 2.4e-15 56.4 2.5 9.5e-11 41.7 0.7 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26770.1 - 5.8e-15 53.9 0.8 4e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD26770.1 - 5.6e-13 48.7 4.9 1.2e-05 25.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat YrzK PF17449.2 PVD26770.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized YrzK-like Heme_oxygenase PF01126.20 PVD26772.1 - 1.1e-55 188.6 0.6 1.5e-55 188.2 0.6 1.2 1 0 0 1 1 1 1 Heme oxygenase Tetraspanin PF00335.20 PVD26773.1 - 2.5e-15 56.8 0.7 4e-15 56.2 0.7 1.2 1 0 0 1 1 1 1 Tetraspanin family Rhodanese PF00581.20 PVD26774.1 - 2.3e-29 102.0 0.0 9.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain PknH_C PF14032.6 PVD26775.1 - 0.038 13.8 4.2 53 3.6 0.1 4.0 1 1 3 4 4 4 0 PknH-like extracellular domain Tet_res_leader PF08050.12 PVD26775.1 - 0.21 11.5 3.6 1.6e+02 2.3 0.0 4.3 4 0 0 4 4 4 0 Tetracycline resistance leader peptide UPF0542 PF15086.6 PVD26775.1 - 5.6 7.0 6.0 1.5e+02 2.4 0.0 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 RT_RNaseH_2 PF17919.1 PVD26776.1 - 4.6e-25 87.6 0.7 1.3e-24 86.2 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD26776.1 - 1.6e-21 76.5 0.0 4.5e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD26776.1 - 1.7e-08 34.3 0.1 2.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 PVD26776.1 - 0.0015 18.5 1.2 0.0053 16.8 1.2 2.0 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 PVD26776.1 - 0.0082 16.7 0.4 0.049 14.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PVD26776.1 - 0.029 15.0 0.4 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC_4 PF14392.6 PVD26776.1 - 0.07 12.9 1.1 0.2 11.4 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF2703 PF10865.8 PVD26776.1 - 1.3 9.3 4.7 9.3 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) LSM PF01423.22 PVD26777.1 - 4.4e-18 64.7 0.4 5.9e-18 64.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 PVD26777.1 - 1.4 9.5 7.1 0.36 11.4 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) FKBP_C PF00254.28 PVD26778.1 - 2.7e-36 123.8 0.0 4.7e-36 123.0 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-AN1 PF01428.16 PVD26779.1 - 1.6e-06 28.2 6.5 1.6e-06 28.2 6.5 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.16 PVD26779.1 - 2.2e-06 27.5 4.3 2.2e-06 27.5 4.3 2.4 2 0 0 2 2 2 1 A20-like zinc finger DUF3563 PF12086.8 PVD26779.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) PIH1 PF08190.12 PVD26781.1 - 1.5e-55 187.2 1.1 2.6e-55 186.4 0.1 2.0 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 PVD26781.1 - 2e-27 95.5 0.1 5e-27 94.2 0.1 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain Bromodomain PF00439.25 PVD26781.1 - 3.4e-23 81.5 0.0 7.9e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain WAC_Acf1_DNA_bd PF10537.9 PVD26781.1 - 5.9e-22 78.1 0.1 6e-21 74.9 0.1 2.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 PVD26781.1 - 2e-14 53.9 0.0 2e-14 53.9 0.0 5.0 4 1 0 4 4 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 PVD26781.1 - 2.4e-12 46.9 2.8 4.5e-12 46.1 1.3 2.3 2 0 0 2 2 2 1 DDT domain PHD PF00628.29 PVD26781.1 - 1.4e-09 37.7 14.3 1.5e-08 34.4 7.8 3.2 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.6 PVD26781.1 - 5.5e-09 35.4 0.0 1.5e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 zf-HC5HC2H PF13771.6 PVD26781.1 - 0.00034 20.8 4.3 0.00092 19.4 3.0 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain Meckelin PF09773.9 PVD26781.1 - 0.074 11.1 0.2 0.17 9.9 0.2 1.5 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Zf_RING PF16744.5 PVD26781.1 - 1.7 8.8 5.9 6.7 6.9 5.9 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger Prim_Zn_Ribbon PF08273.12 PVD26781.1 - 1.9 8.9 5.4 20 5.5 0.2 3.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Atg14 PF10186.9 PVD26782.1 - 1.3e-40 139.5 12.0 1.6e-40 139.1 12.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HpaB_N PF11794.8 PVD26782.1 - 0.023 14.4 2.4 0.038 13.7 2.4 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Terminase_6C PF17289.2 PVD26782.1 - 0.064 13.3 1.0 0.1 12.7 1.0 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain AAA_13 PF13166.6 PVD26782.1 - 0.099 11.3 8.8 0.14 10.8 8.8 1.1 1 0 0 1 1 1 0 AAA domain DUF630 PF04783.12 PVD26782.1 - 0.46 10.7 10.2 0.4 10.9 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF630) TSC22 PF01166.18 PVD26782.1 - 0.57 10.5 5.5 1.8 9.0 1.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF745 PF05335.13 PVD26782.1 - 1.1 9.0 12.8 2.2 8.0 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 PVD26782.1 - 3.3 7.2 11.3 5.7 6.4 11.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 PVD26782.1 - 8.7 5.1 18.0 14 4.5 18.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AMPK1_CBM PF16561.5 PVD26783.1 - 4.8e-33 113.2 0.0 7.4e-33 112.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 PVD26783.1 - 2.9e-26 91.5 2.5 5.9e-26 90.5 2.5 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 PVD26783.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 PVD26783.1 - 0.18 12.4 0.0 0.42 11.2 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Redoxin PF08534.10 PVD26784.1 - 6.9e-21 74.5 0.2 8.6e-21 74.2 0.2 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PVD26784.1 - 5.9e-09 35.9 0.0 7.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RVT_1 PF00078.27 PVD26785.1 - 8.6e-10 38.5 0.1 9.2e-10 38.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mesd PF10185.9 PVD26785.1 - 0.019 14.9 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor CYLD_phos_site PF16607.5 PVD26786.1 - 0.011 15.6 0.7 0.019 14.8 0.1 1.7 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured Med1 PF10744.9 PVD26786.1 - 0.042 12.9 2.3 0.057 12.5 2.3 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Taxilin PF09728.9 PVD26786.1 - 0.11 11.7 15.1 0.012 14.8 10.0 1.8 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Exonuc_VII_L PF02601.15 PVD26786.1 - 0.57 9.7 6.0 0.78 9.3 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Exo_endo_phos PF03372.23 PVD26787.1 - 0.0048 16.5 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HrpB7 PF09486.10 PVD26788.1 - 0.022 15.2 13.1 0.047 14.1 13.1 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FemAB PF02388.16 PVD26788.1 - 0.8 8.5 3.8 1.6 7.6 3.8 1.3 1 0 0 1 1 1 0 FemAB family Spc24 PF08286.11 PVD26788.1 - 6.9 7.0 7.8 1.2 9.4 1.8 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L14 PF00238.19 PVD26789.1 - 6.9e-16 58.4 0.0 1.9e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e FAD_binding_3 PF01494.19 PVD26791.1 - 5.8e-18 65.2 0.0 3.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 PVD26791.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 PVD26791.1 - 0.0082 16.3 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD26791.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PVD26791.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CARD PF00619.21 PVD26792.1 - 1.2e-12 47.6 0.1 3.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 PVD26792.1 - 7.9e-07 29.0 0.0 0.033 14.2 0.1 2.3 2 0 0 2 2 2 2 Caspase recruitment domain TraT PF05818.12 PVD26792.1 - 0.086 12.5 0.5 0.15 11.8 0.5 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Carbam_trans_N PF02543.15 PVD26793.1 - 0.2 11.3 0.4 0.36 10.5 0.4 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Ank_2 PF12796.7 PVD26794.1 - 3.9e-78 258.1 20.5 9.9e-15 54.9 0.1 8.5 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD26794.1 - 8.8e-63 207.9 29.3 9e-09 35.7 0.2 13.3 5 4 9 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26794.1 - 4.1e-48 155.8 27.4 0.00019 21.6 0.1 16.5 17 0 0 17 17 17 12 Ankyrin repeat Ank_5 PF13857.6 PVD26794.1 - 1.7e-44 149.3 32.0 4.7e-06 26.8 0.2 12.0 6 4 6 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 PVD26794.1 - 3.7e-40 134.7 48.9 4.9e-05 23.6 0.1 15.4 15 1 1 16 16 16 13 Ankyrin repeat RVT_1 PF00078.27 PVD26795.1 - 0.00059 19.4 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD26796.1 - 0.0038 16.8 0.2 0.007 15.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 PVD26797.1 - 6e-09 35.9 23.5 0.00048 20.4 0.8 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD26797.1 - 6.8e-07 29.6 18.7 0.0048 17.6 1.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 PVD26797.1 - 1.3e-06 28.6 17.0 0.025 15.0 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD26797.1 - 5.2e-05 23.1 16.1 0.087 12.9 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD26797.1 - 0.012 15.9 17.8 2.6 8.4 0.3 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding MGC-24 PF05283.11 PVD26797.1 - 0.033 14.6 0.2 0.033 14.6 0.2 3.9 3 2 1 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf_UBZ PF18439.1 PVD26797.1 - 0.062 12.9 11.2 0.39 10.4 0.8 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 PVD26797.1 - 0.73 9.9 4.1 6.1 6.9 0.2 3.3 2 1 1 3 3 3 0 CpXC protein zinc-ribbons_6 PF07191.12 PVD26797.1 - 2.6 8.1 10.9 16 5.6 5.4 3.6 3 1 1 4 4 4 0 zinc-ribbons Pkinase PF00069.25 PVD26798.1 - 5.2e-72 242.4 1.0 6.3e-72 242.1 1.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26798.1 - 1.9e-42 145.3 0.2 2.4e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD26798.1 - 4.1e-08 32.9 0.0 6.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD26798.1 - 1.2e-05 24.8 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD26798.1 - 0.00056 19.0 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kei1 PF08552.11 PVD26798.1 - 0.68 9.8 2.7 1.1 9.2 2.7 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pkinase PF00069.25 PVD26799.1 - 9.4e-36 123.5 0.0 4.3e-32 111.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26799.1 - 1.6e-17 63.7 0.0 2.8e-15 56.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD26799.1 - 4.3e-06 26.3 0.0 1.4e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Atrophin-1 PF03154.15 PVD26799.1 - 0.00015 20.2 11.2 0.0002 19.9 11.2 1.1 1 0 0 1 1 1 1 Atrophin-1 family Haspin_kinase PF12330.8 PVD26799.1 - 0.0038 16.2 1.0 0.0062 15.5 0.9 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD26799.1 - 0.011 15.7 0.2 0.063 13.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3915 PF13054.6 PVD26799.1 - 0.27 11.2 10.0 0.5 10.4 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Phage_Gp23 PF10669.9 PVD26799.1 - 2.5 8.4 12.7 2.9 8.3 11.2 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.32 PVD26800.1 - 2.5e-10 40.8 18.3 0.0016 19.2 0.0 8.2 10 0 0 10 10 10 3 WD domain, G-beta repeat Nup160 PF11715.8 PVD26800.1 - 7.3e-05 21.6 0.2 0.69 8.5 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PVD26800.1 - 0.011 16.0 0.0 0.29 11.5 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PVD26800.1 - 0.017 13.9 0.2 1.8 7.2 0.1 2.6 2 1 0 2 2 2 0 Nup133 N terminal like PPP4R2 PF09184.11 PVD26800.1 - 0.24 10.9 5.6 0.42 10.2 5.6 1.2 1 0 0 1 1 1 0 PPP4R2 DUF3678 PF12435.8 PVD26800.1 - 8.3 5.9 8.7 30 4.1 8.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Peptidase_S8 PF00082.22 PVD26803.1 - 1.3e-30 106.7 7.0 7.9e-16 58.2 5.8 2.2 1 1 1 2 2 2 2 Subtilase family P_proprotein PF01483.20 PVD26803.1 - 6.4e-21 74.2 0.1 1.7e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 PVD26803.1 - 2.7e-11 44.1 0.7 5e-11 43.2 0.7 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Annexin PF00191.20 PVD26804.1 - 7.4e-52 173.3 4.2 1.6e-15 56.9 0.2 4.1 4 0 0 4 4 4 4 Annexin OST-HTH PF12872.7 PVD26804.1 - 0.053 13.4 0.1 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 OST-HTH/LOTUS domain SAM_Exu PF18609.1 PVD26804.1 - 0.089 12.9 3.7 0.15 12.2 0.1 2.8 4 0 0 4 4 4 0 Exuperantia SAM-like domain Annexin PF00191.20 PVD26805.1 - 2.2e-20 72.5 0.8 0.00018 21.5 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF1539 PF07560.11 PVD26805.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) KIAA1430 PF13879.6 PVD26806.1 - 8.6e-14 52.1 1.8 8.6e-14 52.1 1.8 1.8 2 0 0 2 2 1 1 KIAA1430 homologue CT47 PF15623.6 PVD26806.1 - 7.1e-06 26.1 2.4 7.1e-06 26.1 2.4 2.0 2 0 0 2 2 1 1 Cancer/testis gene family 47 PBP1_TM PF14812.6 PVD26806.1 - 0.0032 17.8 7.0 0.0032 17.8 7.0 3.1 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Radial_spoke PF04712.12 PVD26806.1 - 0.0086 15.1 10.8 0.0084 15.1 4.4 2.2 2 0 0 2 2 2 1 Radial spokehead-like protein Pox_Ag35 PF03286.14 PVD26806.1 - 0.018 14.8 14.9 0.083 12.7 4.6 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 PVD26806.1 - 0.038 13.3 23.2 0.046 13.0 8.4 2.2 2 0 0 2 2 2 0 NOA36 protein ANAPC15 PF15243.6 PVD26806.1 - 0.3 11.5 23.7 0.53 10.7 10.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RPN2_C PF18004.1 PVD26806.1 - 0.9 9.4 14.0 0.28 11.1 4.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain eIF3_subunit PF08597.10 PVD26806.1 - 1.1 9.1 20.8 0.17 11.8 9.8 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PTPRCAP PF15713.5 PVD26806.1 - 1.6 9.0 24.6 0.99 9.7 5.3 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 PVD26806.1 - 2.4 8.0 18.5 0.69 9.8 8.5 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.12 PVD26806.1 - 2.5 8.0 14.4 0.79 9.7 4.8 2.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PPP4R2 PF09184.11 PVD26806.1 - 4.4 6.8 19.8 1.4 8.5 8.5 2.1 2 0 0 2 2 2 0 PPP4R2 BNIP3 PF06553.12 PVD26806.1 - 4.9 6.8 8.8 0.13 11.9 2.0 1.7 2 0 0 2 2 2 0 BNIP3 TFB6 PF17110.5 PVD26806.1 - 5.8 6.6 10.0 1.5 8.6 2.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 PVD26806.1 - 5.8 6.9 27.9 0.63 10.1 8.0 2.7 1 1 1 2 2 2 0 RXT2-like, N-terminal CPSF100_C PF13299.6 PVD26806.1 - 6.1 7.0 7.2 4.3 7.5 1.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4484 PF14831.6 PVD26806.1 - 7.8 6.5 11.5 2.9 7.9 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DNA_pol_phi PF04931.13 PVD26806.1 - 8.5 4.3 25.1 0.4 8.7 12.8 2.2 2 0 0 2 2 2 0 DNA polymerase phi LRR_8 PF13855.6 PVD26807.1 - 6.1e-30 102.8 37.7 3e-08 33.3 3.7 7.1 4 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD26807.1 - 5.1e-15 55.3 41.6 0.0004 20.7 2.3 9.7 4 4 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD26807.1 - 4.3e-08 33.2 13.7 0.0005 20.0 3.0 3.9 2 2 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD26807.1 - 4.4e-05 23.1 10.1 0.014 14.9 0.1 3.9 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 PVD26807.1 - 0.0055 17.1 35.2 1.5 9.6 1.1 11.6 10 3 0 10 10 10 1 Leucine Rich Repeat DUF4325 PF14213.6 PVD26807.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) LRR_6 PF13516.6 PVD26807.1 - 1.3 9.2 0.0 1.3 9.2 0.0 10.9 12 0 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.6 PVD26809.1 - 2.1e-47 158.7 64.2 4.7e-08 32.7 0.0 11.7 8 3 3 11 11 11 9 Leucine rich repeat TIR PF01582.20 PVD26809.1 - 3.2e-29 101.9 3.2 2.5e-19 69.8 0.4 2.3 2 0 0 2 2 2 2 TIR domain TIR_2 PF13676.6 PVD26809.1 - 5.1e-24 85.1 0.3 3.1e-16 60.0 0.1 2.8 2 0 0 2 2 2 2 TIR domain LRR_4 PF12799.7 PVD26809.1 - 7.9e-17 61.1 70.6 0.0036 17.7 3.0 14.4 7 5 13 20 20 19 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD26809.1 - 7.6e-11 42.1 18.1 0.0029 17.6 2.1 6.3 4 2 1 5 5 5 3 BspA type Leucine rich repeat region (6 copies) DUF1863 PF08937.11 PVD26809.1 - 1.5e-06 28.5 0.7 0.0024 18.2 0.0 2.6 2 0 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) LRR_9 PF14580.6 PVD26809.1 - 1.1e-05 25.1 21.5 0.043 13.3 0.0 5.4 4 1 2 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 PVD26809.1 - 0.00039 20.6 53.2 0.88 10.4 0.8 16.7 17 3 0 17 17 16 3 Leucine Rich Repeat DUF4325 PF14213.6 PVD26809.1 - 0.007 16.1 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 2 STAS-like domain of unknown function (DUF4325) LRRCT PF01463.24 PVD26809.1 - 0.0099 16.4 0.1 1.4 9.6 0.1 3.5 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain TIR_3 PF18567.1 PVD26809.1 - 0.031 14.3 1.0 0.099 12.6 0.2 2.4 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain DUF1944 PF09175.10 PVD26809.1 - 0.12 12.2 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) Peptidase_M28 PF04389.17 PVD26810.1 - 1.9e-06 27.7 0.0 2.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.17 PVD26812.1 - 0.00037 20.3 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD26812.1 - 0.0071 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF5314 PF17241.2 PVD26812.1 - 0.12 12.0 0.3 0.28 10.8 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5314) Phage_GP20 PF06810.11 PVD26812.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Keratin_2_head PF16208.5 PVD26813.1 - 3.5e-07 30.5 23.6 0.00041 20.5 10.8 2.1 2 0 0 2 2 2 2 Keratin type II head KRTAP PF11759.8 PVD26813.1 - 1.6e-06 28.6 25.4 0.00088 19.8 12.0 2.3 2 0 0 2 2 2 2 Keratin-associated matrix MspA PF09203.11 PVD26813.1 - 0.00069 19.5 14.9 0.003 17.5 4.9 2.1 2 0 0 2 2 2 2 MspA OMP_b-brl PF13505.6 PVD26813.1 - 3.1 7.9 17.0 95 3.1 17.0 2.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain SRCR PF00530.18 PVD26814.1 - 3.4e-12 46.7 1.0 7.9e-12 45.6 1.0 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD26814.1 - 0.0019 18.7 0.2 0.064 13.8 0.0 2.8 3 0 0 3 3 3 1 Hepsin, SRCR domain eIF-3c_N PF05470.12 PVD26814.1 - 0.053 11.8 2.2 0.073 11.4 2.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SRCR_2 PF15494.6 PVD26814.1 - 0.053 14.1 0.3 0.22 12.1 0.1 2.1 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain CENP-B_dimeris PF09026.10 PVD26814.1 - 0.65 10.4 23.6 1.8 9.0 23.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 PVD26814.1 - 1.1 8.5 10.2 1.7 7.9 10.2 1.3 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 PVD26815.1 - 8.7e-41 139.9 0.0 9.9e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_5 PF12688.7 PVD26815.1 - 0.13 12.5 0.9 0.25 11.6 0.0 2.0 3 0 0 3 3 3 0 Tetratrico peptide repeat SRCR PF00530.18 PVD26816.1 - 8.7e-05 23.0 0.5 0.00019 21.8 0.2 1.8 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PVD26817.1 - 2.5e-17 63.2 0.2 1.3e-08 35.2 0.1 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ig_2 PF13895.6 PVD26817.1 - 3.6e-08 33.6 1.2 4.3e-07 30.2 0.2 2.5 1 1 1 2 2 2 1 Immunoglobulin domain RVT_1 PF00078.27 PVD26817.1 - 7.6e-08 32.1 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_3 PF13927.6 PVD26817.1 - 8.6e-08 32.7 0.5 5.3e-07 30.1 0.1 2.3 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD26817.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD26817.1 - 8.6e-07 29.1 0.1 3e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 PVD26817.1 - 0.048 13.8 1.1 2.2 8.5 1.1 2.3 1 1 0 1 1 1 0 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD26817.1 - 0.057 13.5 0.1 0.79 9.8 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain gag-asp_proteas PF13975.6 PVD26818.1 - 6.8e-05 23.3 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PNMA PF14893.6 PVD26818.1 - 0.00092 18.7 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 PNMA Asp_protease_2 PF13650.6 PVD26818.1 - 0.0061 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 PVD26818.1 - 0.056 13.5 3.0 0.13 12.4 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 PVD26818.1 - 0.069 13.5 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Exo_endo_phos_2 PF14529.6 PVD26819.1 - 0.083 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Fn3-like PF14310.6 PVD26819.1 - 0.15 12.2 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type III-like domain TSP_1 PF00090.19 PVD26820.1 - 1.2e-19 70.2 33.1 2.1e-11 43.9 18.1 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_3 PF13927.6 PVD26820.1 - 1.5e-18 67.1 9.6 5.9e-08 33.2 0.4 4.5 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD26820.1 - 1.2e-16 60.6 7.7 1.5e-05 25.0 0.2 4.6 5 1 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD26820.1 - 3.5e-11 43.3 19.0 1.1e-05 25.6 0.3 5.0 4 1 1 5 5 5 2 Immunoglobulin domain ig PF00047.25 PVD26820.1 - 3.2e-08 33.6 9.9 0.003 17.7 0.4 4.3 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD26820.1 - 2.7e-07 30.7 7.4 0.0021 18.2 0.1 4.7 4 2 1 5 5 5 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 PVD26820.1 - 0.033 14.2 0.2 2.8 8.0 0.1 2.9 2 0 0 2 2 2 0 C17orf99 Ig domain I-set PF07679.16 PVD26821.1 - 5.9e-13 48.7 0.7 3.8e-06 26.9 0.2 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26821.1 - 7.1e-10 39.4 1.5 2.1e-06 28.2 0.4 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD26821.1 - 8.7e-07 29.1 1.0 0.0069 16.6 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD26821.1 - 3.9e-06 27.1 2.7 3e-05 24.3 0.9 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD26821.1 - 0.00027 21.1 2.5 0.0018 18.4 0.6 2.6 2 1 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD26821.1 - 0.0071 16.5 0.2 2 8.7 0.1 2.3 2 0 0 2 2 2 2 Natural killer cell receptor 2B4 Cadherin-like PF12733.7 PVD26821.1 - 0.54 10.8 3.6 2.1 9.0 1.0 2.5 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain RNase_H PF00075.24 PVD26822.1 - 4.8e-13 49.5 0.0 1.5e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 PVD26822.1 - 0.005 16.6 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like I-set PF07679.16 PVD26824.1 - 6.8e-12 45.3 0.8 7.9e-05 22.6 0.1 3.0 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26824.1 - 6.2e-08 33.1 1.5 7.5e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD26824.1 - 2e-07 31.2 2.5 0.0098 16.1 0.1 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD26824.1 - 2e-05 24.8 2.8 0.00012 22.3 0.7 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD26824.1 - 0.0089 16.2 2.5 0.071 13.3 0.8 2.9 3 1 0 3 3 3 1 Immunoglobulin domain Ank_4 PF13637.6 PVD26826.1 - 5.5e-14 52.3 3.3 0.00022 21.7 0.1 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD26826.1 - 6.7e-13 47.6 2.7 0.00011 22.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PVD26826.1 - 6.9e-13 48.5 6.0 0.00017 21.8 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD26826.1 - 5.2e-12 45.6 2.6 5.3e-05 23.5 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 PVD26826.1 - 7.4e-12 45.7 1.9 0.00055 20.5 0.0 3.2 1 1 0 3 3 3 2 Ankyrin repeats (3 copies) DUF5535 PF17687.1 PVD26826.1 - 0.072 13.3 0.0 0.3 11.3 0.0 1.9 2 1 1 3 3 3 0 Family of unknown function (DUF5535) Ank_4 PF13637.6 PVD26827.1 - 3e-37 126.5 15.9 2.9e-06 27.7 0.0 10.3 5 5 3 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD26827.1 - 6.8e-37 125.1 21.0 2.2e-05 24.7 0.1 9.9 10 3 1 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26827.1 - 4.6e-32 110.5 13.9 2.4e-05 24.8 0.0 9.2 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26827.1 - 7.9e-32 105.7 11.0 0.072 13.7 0.0 14.2 14 0 0 14 14 14 8 Ankyrin repeat Ank PF00023.30 PVD26827.1 - 1.1e-27 95.2 16.6 0.00045 20.5 0.0 13.9 14 1 1 15 15 15 8 Ankyrin repeat RIC1 PF07064.13 PVD26827.1 - 0.051 13.0 1.7 3.5 7.0 0.0 3.9 5 0 0 5 5 5 0 RIC1 SPACA9 PF15120.6 PVD26827.1 - 0.3 10.9 5.4 3.1 7.5 0.1 3.5 4 0 0 4 4 4 0 Sperm acrosome-associated protein 9 Ank_5 PF13857.6 PVD26829.1 - 4.2e-23 81.1 0.8 1.1e-06 28.8 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD26829.1 - 1.7e-20 73.1 1.7 1.5e-06 28.6 0.0 6.5 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26829.1 - 2.7e-20 72.8 2.8 4.5e-07 30.4 0.2 4.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26829.1 - 1.4e-17 62.0 0.3 0.009 16.5 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PVD26829.1 - 9.9e-17 60.6 6.9 0.00021 21.6 0.0 7.5 8 1 0 8 8 8 5 Ankyrin repeat DUF2093 PF09866.9 PVD26830.1 - 0.11 12.0 3.4 93 2.6 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) Antimicrobial_1 PF08018.11 PVD26830.1 - 0.29 11.3 5.4 63 3.8 0.0 3.9 4 0 0 4 4 4 0 Frog antimicrobial peptide Ank_5 PF13857.6 PVD26831.1 - 8.5e-35 118.4 4.7 1.4e-06 28.5 0.0 6.2 5 1 0 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD26831.1 - 2.4e-27 95.3 8.2 1.2e-07 32.2 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD26831.1 - 3.2e-25 85.4 1.4 0.012 16.1 0.0 9.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 PVD26831.1 - 2.7e-24 85.2 6.6 0.00014 22.3 0.0 8.5 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD26831.1 - 4e-22 77.6 13.0 0.00027 21.2 0.0 9.6 11 0 0 11 11 11 6 Ankyrin repeat Herpes_UL51 PF04540.13 PVD26832.1 - 0.006 16.3 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL51 protein Mito_fiss_reg PF05308.11 PVD26832.1 - 0.054 13.6 5.4 0.061 13.4 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD26832.1 - 0.32 10.4 8.2 0.36 10.3 8.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cwf_Cwc_15 PF04889.12 PVD26833.1 - 8.5e-06 25.7 15.9 1.1e-05 25.4 15.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 PVD26833.1 - 0.0018 18.5 14.1 0.0024 18.1 14.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 PVD26833.1 - 0.0033 16.8 19.4 0.004 16.5 19.4 1.2 1 0 0 1 1 1 1 NOA36 protein PPP4R2 PF09184.11 PVD26833.1 - 0.0034 17.0 10.6 0.004 16.8 10.6 1.1 1 0 0 1 1 1 1 PPP4R2 BUD22 PF09073.10 PVD26833.1 - 0.032 13.6 7.3 0.037 13.4 7.3 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 PVD26833.1 - 0.048 13.7 8.9 0.07 13.1 8.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 PVD26833.1 - 0.12 11.7 12.6 0.17 11.3 12.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PVD26833.1 - 0.19 9.9 12.0 0.21 9.7 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 PVD26833.1 - 0.2 9.9 10.5 0.22 9.8 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 PVD26833.1 - 0.68 9.7 5.9 0.82 9.4 5.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3295 PF11702.8 PVD26833.1 - 1.2 8.4 13.4 1.4 8.2 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2076 PF09849.9 PVD26833.1 - 2.5 8.1 14.8 2.7 8.0 14.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRN3 PF05327.11 PVD26833.1 - 4.4 5.7 15.0 4.7 5.6 15.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIE_beta PF02186.15 PVD26836.1 - 0.081 13.2 0.0 98 3.3 0.0 3.5 4 0 0 4 4 4 0 TFIIE beta subunit core domain I-set PF07679.16 PVD26837.1 - 9.9e-13 48.0 0.5 3.3e-05 23.9 0.2 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26837.1 - 5.6e-09 36.5 0.4 7.7e-06 26.4 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD26837.1 - 1.6e-08 34.7 0.8 0.00055 20.1 0.1 2.6 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD26837.1 - 5.9e-07 29.7 2.3 6.6e-06 26.4 0.7 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD26837.1 - 0.00019 21.5 4.5 0.00024 21.2 0.9 2.3 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 PVD26837.1 - 0.039 13.5 0.3 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD26837.1 - 0.069 13.4 0.1 5.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TSP_1 PF00090.19 PVD26838.1 - 9.3e-10 38.6 10.9 9.3e-10 38.6 10.9 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain I-set PF07679.16 PVD26838.1 - 9.6e-07 28.8 0.0 0.016 15.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26838.1 - 6.8e-06 26.6 0.4 0.015 15.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD26838.1 - 0.00037 20.6 0.9 0.73 10.0 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD26838.1 - 0.0012 19.1 1.1 0.023 15.0 0.5 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ShK PF01549.24 PVD26838.1 - 0.0015 19.1 5.9 0.0015 19.1 5.9 2.6 3 0 0 3 3 3 1 ShK domain-like Ig_6 PF18452.1 PVD26838.1 - 0.064 12.8 0.2 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain OATP PF03137.20 PVD26839.1 - 2.4e-66 224.2 17.4 3.1e-66 223.8 17.4 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 PVD26839.1 - 6.6e-07 29.4 12.0 1.6e-06 28.1 12.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD26839.1 - 0.024 14.6 8.5 0.053 13.5 8.5 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain MFS_1 PF07690.16 PVD26839.1 - 0.1 11.5 18.5 0.06 12.3 5.1 2.7 2 1 0 2 2 2 0 Major Facilitator Superfamily Methyltransf_21 PF05050.12 PVD26840.1 - 1.8e-08 34.6 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 PVD26840.1 - 0.1 11.9 0.3 0.23 10.7 0.3 1.5 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein UDPGT PF00201.18 PVD26841.1 - 7e-75 252.7 0.6 9.9e-75 252.2 0.6 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26841.1 - 8.5e-06 25.8 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 PVD26842.1 - 0.00037 19.4 0.2 0.019 13.8 0.0 2.1 1 1 1 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26843.1 - 3.6e-60 204.2 0.1 4.8e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26843.1 - 3.3e-06 27.2 0.0 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain CTV_P13 PF06922.11 PVD26843.1 - 0.047 13.8 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein UDPGT PF00201.18 PVD26844.1 - 5.1e-31 108.0 0.0 8.1e-30 104.1 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26845.1 - 1.5e-48 165.9 0.1 1.4e-47 162.6 0.0 1.9 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26845.1 - 3.9e-05 23.7 0.0 0.00017 21.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 PVD26846.1 - 5.7e-74 249.7 0.1 9.3e-42 143.5 0.1 2.2 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26847.1 - 2.2e-37 129.0 0.1 3.1e-37 128.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase OATP PF03137.20 PVD26848.1 - 9.3e-131 436.8 19.4 9.9e-131 436.7 18.6 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family UDPGT PF00201.18 PVD26848.1 - 5.5e-43 147.5 0.0 9.1e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.16 PVD26848.1 - 2.3e-14 53.1 22.8 1.9e-12 46.8 10.3 4.0 4 1 0 4 4 4 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD26848.1 - 3.1e-06 27.2 12.2 9.6e-06 25.6 12.2 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD26848.1 - 0.26 11.3 10.9 0.2 11.7 8.6 2.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain UDPGT PF00201.18 PVD26849.1 - 1.5e-58 198.9 1.0 5e-37 127.8 0.0 3.0 1 1 1 3 3 3 3 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26850.1 - 4e-14 52.3 0.1 8.7e-13 47.9 0.0 2.0 1 1 1 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase ABC_tran PF00005.27 PVD26851.1 - 2e-30 106.1 0.0 3.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PVD26851.1 - 4e-27 95.6 7.6 4.6e-27 95.4 5.6 1.9 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 PVD26851.1 - 9.9e-08 31.7 0.0 3.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain Calc_CGRP_IAPP PF00214.19 PVD26851.1 - 0.007 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family MMR_HSR1 PF01926.23 PVD26851.1 - 0.016 15.3 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD26851.1 - 0.028 14.8 0.1 0.062 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 PVD26851.1 - 0.23 11.5 0.3 0.58 10.2 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_membrane PF00664.23 PVD26852.1 - 1e-33 117.2 13.4 1e-33 117.2 13.4 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD26852.1 - 2.7e-20 73.3 0.0 7.6e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD26852.1 - 0.00029 20.8 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 PVD26852.1 - 0.00052 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family SMC_N PF02463.19 PVD26852.1 - 0.00066 19.2 0.1 0.086 12.3 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD26852.1 - 0.0067 16.5 0.1 0.017 15.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 PVD26852.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PVD26852.1 - 0.053 13.9 0.1 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PVD26852.1 - 0.11 12.9 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TMEM154 PF15102.6 PVD26854.1 - 0.46 10.4 3.3 0.8 9.6 3.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family UDPGT PF00201.18 PVD26855.1 - 2.8e-102 343.1 0.5 9e-37 127.0 0.0 3.2 3 0 0 3 3 3 3 UDP-glucoronosyl and UDP-glucosyl transferase Fe_hyd_lg_C PF02906.14 PVD26855.1 - 0.00022 21.0 0.0 0.6 9.7 0.0 3.2 3 0 0 3 3 3 1 Iron only hydrogenase large subunit, C-terminal domain POC1 PF10450.9 PVD26855.1 - 0.0018 17.3 0.9 8.3 5.3 0.0 3.3 3 0 0 3 3 3 3 POC1 chaperone Glyco_transf_4 PF13439.6 PVD26855.1 - 0.024 14.7 0.4 15 5.6 0.0 3.4 4 0 0 4 4 4 0 Glycosyltransferase Family 4 Polysacc_deac_2 PF04748.13 PVD26855.1 - 0.073 12.3 0.0 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Glyco_transf_5 PF08323.11 PVD26855.1 - 0.1 12.3 0.0 18 4.9 0.0 2.5 2 0 0 2 2 2 0 Starch synthase catalytic domain RNA_pol_Rpo13 PF12136.8 PVD26855.1 - 0.61 10.0 3.5 89 3.1 0.1 3.2 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain OATP PF03137.20 PVD26857.1 - 1.4e-110 370.2 16.4 2.2e-60 204.5 0.1 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UDPGT PF00201.18 PVD26857.1 - 7.6e-26 91.0 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.16 PVD26857.1 - 4.7e-11 42.2 24.9 1.1e-06 27.9 5.2 3.8 3 1 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD26857.1 - 2.5e-06 27.5 12.0 6.1e-06 26.3 12.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD26857.1 - 0.018 15.1 6.5 0.046 13.7 6.5 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain CTV_P13 PF06922.11 PVD26857.1 - 0.075 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein Colicin_V PF02674.16 PVD26857.1 - 9 6.3 8.7 5.5 7.0 0.0 3.9 4 0 0 4 4 4 0 Colicin V production protein UDPGT PF00201.18 PVD26858.1 - 2.1e-37 129.1 0.0 3.9e-37 128.2 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26860.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26860.1 - 5.4e-07 29.7 0.0 6.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 PVD26861.1 - 4.8e-114 381.9 1.5 2.4e-57 194.9 0.1 3.0 2 1 1 3 3 3 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26861.1 - 4.8e-13 49.4 0.0 5.6e-06 26.4 0.0 3.1 4 0 0 4 4 4 2 Glycosyltransferase family 28 C-terminal domain Polysacc_deac_2 PF04748.13 PVD26861.1 - 0.012 14.8 0.0 7 5.8 0.0 2.9 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase Glyco_transf_4 PF13439.6 PVD26861.1 - 0.028 14.4 0.6 8.9 6.3 0.0 3.1 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 PVD26861.1 - 0.08 12.6 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Starch synthase catalytic domain Luteo_PO PF04662.13 PVD26861.1 - 0.15 11.7 0.3 14 5.3 0.1 2.5 2 0 0 2 2 2 0 Luteovirus P0 protein UDPGT PF00201.18 PVD26862.1 - 1.2e-78 265.2 0.9 1.5e-78 264.8 0.9 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26862.1 - 3.7e-07 30.3 0.0 1.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain CTV_P13 PF06922.11 PVD26862.1 - 0.14 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein UDPGT PF00201.18 PVD26863.1 - 3.7e-193 642.9 8.7 2.1e-65 221.5 0.8 3.1 2 1 1 3 3 3 3 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26863.1 - 3.4e-21 75.9 0.1 5.6e-06 26.4 0.0 3.9 5 0 0 5 5 5 3 Glycosyltransferase family 28 C-terminal domain CTV_P13 PF06922.11 PVD26863.1 - 0.019 15.0 1.1 5.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein Rad21_Rec8 PF04824.16 PVD26863.1 - 0.043 13.1 0.8 15 4.9 0.0 3.4 3 0 0 3 3 3 0 Conserved region of Rad21 / Rec8 like protein Polysacc_deac_2 PF04748.13 PVD26863.1 - 0.046 12.9 0.0 12 5.0 0.0 3.3 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase DUF4924 PF16271.5 PVD26863.1 - 0.053 13.5 4.7 8.3 6.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4924) Gp_dh_C PF02800.20 PVD26863.1 - 0.056 13.0 3.0 23 4.5 0.0 3.3 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Binary_toxB_2 PF17475.2 PVD26863.1 - 0.092 12.4 0.6 29 4.3 0.0 3.1 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA domain 2 Glyco_transf_4 PF13439.6 PVD26863.1 - 0.095 12.7 0.1 30 4.5 0.0 3.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 F-box PF00646.33 PVD26863.1 - 0.098 12.6 0.4 27 4.8 0.0 2.9 2 0 0 2 2 2 0 F-box domain Fe_hyd_lg_C PF02906.14 PVD26863.1 - 0.15 11.7 0.0 26 4.4 0.0 3.1 3 0 0 3 3 3 0 Iron only hydrogenase large subunit, C-terminal domain SH PF01445.17 PVD26863.1 - 0.29 11.1 3.8 7.4 6.6 0.0 4.2 4 0 0 4 4 4 0 Viral small hydrophobic protein HHH_3 PF12836.7 PVD26863.1 - 0.73 10.1 3.4 1.5e+02 2.7 0.1 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif RNA_pol_Rpo13 PF12136.8 PVD26863.1 - 1.6 8.7 3.5 1.3e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain UDPGT PF00201.18 PVD26864.1 - 2.5e-30 105.8 0.2 1.5e-20 73.5 0.0 3.7 3 1 1 4 4 4 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD26864.1 - 0.00059 19.8 0.0 0.0053 16.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase family 28 C-terminal domain DUF4467 PF14729.6 PVD26864.1 - 0.0021 18.4 0.0 0.83 10.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function with cystatin-like fold (DUF4467) Polysacc_deac_2 PF04748.13 PVD26864.1 - 0.01 15.1 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 2 Divergent polysaccharide deacetylase Glyco_transf_4 PF13439.6 PVD26864.1 - 0.01 15.9 0.5 5.2 7.0 0.1 3.0 2 2 0 2 2 2 0 Glycosyltransferase Family 4 IncF PF17626.2 PVD26864.1 - 0.062 13.7 1.3 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Inclusion membrane protein F Glyco_transf_5 PF08323.11 PVD26864.1 - 0.064 12.9 0.0 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Starch synthase catalytic domain UDPGT PF00201.18 PVD26865.1 - 6.1e-31 107.8 0.0 7.1e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD26866.1 - 2.6e-21 76.0 0.1 4.2e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase OATP PF03137.20 PVD26867.1 - 3.3e-35 121.4 8.9 4.4e-35 121.0 8.9 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 PVD26867.1 - 7.4e-07 29.2 12.8 7.4e-07 29.2 12.8 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD26867.1 - 0.024 14.7 10.7 0.061 13.3 10.7 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain SRCR PF00530.18 PVD26868.1 - 1.1e-08 35.4 0.2 1.1e-08 35.4 0.2 2.4 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain MgrB PF13998.6 PVD26868.1 - 0.4 10.6 1.8 0.47 10.4 0.1 2.0 2 0 0 2 2 2 0 MgrB protein Gal_Lectin PF02140.18 PVD26868.1 - 9.7 6.7 12.4 0.21 12.1 0.3 3.6 4 0 0 4 4 4 0 Galactose binding lectin domain MACPF PF01823.19 PVD26869.1 - 2.6e-16 60.4 0.9 8.4e-16 58.7 0.6 1.9 1 1 0 1 1 1 1 MAC/Perforin domain EB PF01683.18 PVD26869.1 - 0.015 15.6 7.1 0.015 15.6 7.1 2.7 2 2 0 2 2 2 0 EB module cEGF PF12662.7 PVD26869.1 - 0.026 14.4 1.4 0.067 13.1 1.4 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like PAN_2 PF08276.11 PVD26869.1 - 0.069 13.3 0.0 0.069 13.3 0.0 3.4 3 1 1 4 4 4 0 PAN-like domain PAN_3 PF08277.12 PVD26869.1 - 0.19 11.5 14.5 0.22 11.3 1.6 3.2 4 0 0 4 4 4 0 PAN-like domain PAN_4 PF14295.6 PVD26869.1 - 0.26 11.2 7.7 3.7 7.5 2.4 3.0 3 0 0 3 3 3 0 PAN domain I-set PF07679.16 PVD26870.1 - 3.6e-05 23.8 1.8 0.014 15.5 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD26870.1 - 0.011 16.1 1.7 0.68 10.3 0.1 2.8 3 0 0 3 3 3 0 Immunoglobulin domain ig PF00047.25 PVD26870.1 - 0.034 14.3 0.4 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain DUF3306 PF11748.8 PVD26870.1 - 0.037 14.9 0.3 0.061 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SKG6 PF08693.10 PVD26870.1 - 0.064 12.7 0.3 0.22 11.0 0.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ig_3 PF13927.6 PVD26870.1 - 1.2 9.8 6.4 14 6.3 0.3 2.9 3 0 0 3 3 3 0 Immunoglobulin domain MgrB PF13998.6 PVD26871.1 - 0.18 11.7 0.8 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 MgrB protein ABC_membrane PF00664.23 PVD26872.1 - 1e-56 192.7 16.6 9.5e-32 110.7 4.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD26872.1 - 5.7e-42 143.5 0.0 1.1e-27 97.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD26872.1 - 7.6e-09 35.3 0.0 6.2e-05 22.5 0.0 2.9 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Bestrophin PF01062.21 PVD26873.1 - 3.1e-59 200.8 10.5 6.9e-53 179.9 4.4 2.3 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel SRP-alpha_N PF04086.13 PVD26874.1 - 1.1e-56 193.0 19.0 1.5e-56 192.5 19.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 PVD26874.1 - 2.3e-48 164.4 0.4 1.5e-47 161.8 0.5 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 PVD26874.1 - 2.1e-08 34.3 1.8 4.3e-08 33.3 0.0 2.6 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 PVD26874.1 - 6.4e-05 22.1 0.1 0.00019 20.5 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 PVD26874.1 - 0.00016 21.8 0.0 0.00075 19.6 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain RINT1_TIP1 PF04437.13 PVD26874.1 - 0.00048 19.1 0.1 0.00078 18.5 0.1 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family NTPase_1 PF03266.15 PVD26874.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 PVD26874.1 - 0.0062 16.9 0.0 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Fer4_NifH PF00142.18 PVD26874.1 - 0.008 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Glyco_trans_A_1 PF09318.10 PVD26874.1 - 0.021 14.5 2.3 0.034 13.9 1.9 1.5 1 1 0 1 1 1 0 Glycosyl transferase 1 domain A MMR_HSR1 PF01926.23 PVD26874.1 - 0.09 12.9 0.2 0.98 9.5 0.2 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Urb2 PF10441.9 PVD26875.1 - 0.002 18.1 2.0 0.002 18.1 2.0 3.2 3 1 0 3 3 3 1 Urb2/Npa2 family RNA_pol_Rpb4 PF03874.16 PVD26875.1 - 5.3 7.4 6.9 10 6.5 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase Rpb4 Pou PF00157.17 PVD26876.1 - 1.6e-36 124.1 0.1 1.6e-36 124.1 0.1 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 PVD26876.1 - 5.1e-18 64.7 0.9 1.4e-17 63.2 0.9 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 PVD26876.1 - 0.064 13.6 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Miff PF05644.11 PVD26876.1 - 8 6.0 13.3 1.4 8.5 6.2 2.3 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF2710 PF10921.8 PVD26877.1 - 0.035 14.5 0.1 0.066 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) CCDC84 PF14968.6 PVD26878.1 - 5.4e-55 187.4 5.9 4.8e-54 184.3 5.9 2.1 1 1 0 1 1 1 1 Coiled coil protein 84 G_path_suppress PF15991.5 PVD26879.1 - 7.9e-54 183.7 42.7 7.2e-52 177.3 42.7 2.1 1 1 0 1 1 1 1 G-protein pathway suppressor MIF4G_like_2 PF09090.11 PVD26879.1 - 1.6 8.1 11.1 2.8 7.3 11.1 1.3 1 0 0 1 1 1 0 MIF4G like NBP1 PF08537.10 PVD26879.1 - 2.4 7.5 14.4 3.9 6.8 14.4 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Pkinase_Tyr PF07714.17 PVD26880.1 - 8.6e-93 310.3 0.0 1.3e-92 309.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD26880.1 - 3.6e-44 151.1 0.0 9.1e-44 149.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain I-set PF07679.16 PVD26880.1 - 2.8e-23 81.8 4.7 1.8e-09 37.5 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD26880.1 - 2.7e-22 79.2 12.3 2.2e-06 28.2 0.2 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 PVD26880.1 - 1.4e-14 54.0 12.3 6.6e-05 23.0 0.2 4.6 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD26880.1 - 2.6e-09 37.3 11.2 0.00063 20.0 0.2 4.2 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 PVD26880.1 - 7.3e-06 26.1 8.6 0.11 12.7 0.0 5.3 4 1 0 4 4 4 2 Immunoglobulin V-set domain Pkinase_fungal PF17667.1 PVD26880.1 - 0.00084 18.2 0.2 0.0019 17.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Chordopox_A13L PF05961.11 PVD26880.1 - 0.073 13.3 2.4 0.16 12.3 0.3 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF5385 PF17359.2 PVD26880.1 - 0.13 11.8 0.5 0.24 10.9 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Methyltransf_21 PF05050.12 PVD26882.1 - 8.6e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 PVD26882.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Met_10 PF02475.16 PVD26882.1 - 0.005 16.6 0.2 0.0066 16.2 0.2 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Lipase_GDSL_2 PF13472.6 PVD26883.1 - 5.5e-13 49.7 0.0 7.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PVD26883.1 - 3.5e-05 23.9 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 PVD26883.1 - 0.0012 19.0 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ABC2_membrane PF01061.24 PVD26884.1 - 2.2e-42 144.8 29.3 3.3e-42 144.3 29.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD26884.1 - 5.3e-27 95.0 0.0 8.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD26884.1 - 7.2e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD26884.1 - 1.4e-06 28.4 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PVD26884.1 - 2.3e-05 24.3 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PVD26884.1 - 0.00026 20.7 1.1 0.00075 19.2 0.4 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PVD26884.1 - 0.0026 18.3 0.0 0.0057 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD26884.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD26884.1 - 0.035 14.5 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PVD26884.1 - 0.062 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD26884.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 PVD26884.1 - 0.089 12.4 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 PVD26884.1 - 0.11 12.7 0.1 1.8 8.9 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 PVD26884.1 - 0.15 10.7 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 PVD26884.1 - 0.23 10.6 29.9 0.14 11.2 16.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein IQ PF00612.27 PVD26885.1 - 2.4e-35 117.0 13.8 3.3e-05 23.3 0.3 6.3 6 0 0 6 6 6 6 IQ calmodulin-binding motif Yop-YscD_cpl PF16697.5 PVD26885.1 - 1.3e-07 31.9 0.2 2 8.8 0.0 4.4 2 2 2 4 4 4 3 Inner membrane component of T3SS, cytoplasmic domain YadA_head PF05658.14 PVD26885.1 - 0.049 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin DUF1823 PF08853.11 PVD26885.1 - 0.12 12.6 0.3 3.9 7.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1823) Apolipoprotein PF01442.18 PVD26886.1 - 2.9e-05 24.0 35.3 2.9e-05 24.0 35.3 4.9 1 1 2 4 4 4 2 Apolipoprotein A1/A4/E domain IKKbetaNEMObind PF12179.8 PVD26886.1 - 0.083 12.9 0.7 23 5.2 0.0 3.9 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain RPA_interact_M PF14767.6 PVD26888.1 - 1.1 9.9 20.0 0.52 10.9 6.0 3.3 2 1 0 2 2 2 0 Replication protein A interacting middle Dak2 PF02734.17 PVD26888.1 - 8.1 6.3 7.3 35 4.2 0.1 2.5 2 0 0 2 2 2 0 DAK2 domain RsbRD_N PF14361.6 PVD26889.1 - 0.037 14.7 0.6 0.13 13.0 0.2 2.0 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain BTB PF00651.31 PVD26890.1 - 2.1e-20 73.0 0.2 3.7e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 PVD26890.1 - 7.4e-19 67.3 1.4 4.4e-07 30.0 0.1 5.3 2 1 3 5 5 5 3 Kelch motif BACK PF07707.15 PVD26890.1 - 5.3e-16 58.6 2.1 6.2e-16 58.4 0.4 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD26890.1 - 2.4e-11 43.0 1.6 0.0009 18.8 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 PVD26890.1 - 5.9e-11 41.9 2.5 5e-05 23.1 0.1 5.3 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PVD26890.1 - 9.8e-07 28.9 0.9 0.017 15.4 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD26890.1 - 1.2e-05 25.2 1.2 2.3 8.3 0.0 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD26890.1 - 1.7e-05 24.7 1.0 0.0074 16.3 0.1 4.0 3 1 0 3 3 3 1 Kelch motif DUF3342 PF11822.8 PVD26890.1 - 0.012 15.7 0.2 0.032 14.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.25 PVD26891.1 - 1.2e-66 224.8 0.0 2.4e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26891.1 - 4e-35 121.3 0.0 6.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD26891.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD26891.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD26891.1 - 0.024 13.4 0.0 0.024 13.4 0.0 2.3 2 1 0 2 2 2 0 Fungal protein kinase Macoilin PF09726.9 PVD26891.1 - 0.16 10.5 6.4 0.21 10.1 6.4 1.1 1 0 0 1 1 1 0 Macoilin family Colipase_C PF02740.14 PVD26893.1 - 0.69 10.1 12.3 5.8 7.2 3.0 3.1 2 1 0 2 2 2 0 Colipase, C-terminal domain Flexi_CP PF00286.20 PVD26893.1 - 2.6 8.0 7.1 9.9 6.1 0.4 3.0 3 1 0 3 3 3 0 Viral coat protein DAG1 PF05454.11 PVD26894.1 - 0.013 14.9 0.1 0.013 14.9 0.1 3.1 4 0 0 4 4 4 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 PVD26894.1 - 0.21 12.5 6.1 22 6.0 0.0 4.6 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain Endotoxin_C PF03944.14 PVD26895.1 - 0.01 16.2 0.0 4.1 7.7 0.0 2.3 2 0 0 2 2 2 0 delta endotoxin TMEM154 PF15102.6 PVD26896.1 - 0.047 13.6 0.6 0.091 12.7 0.6 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 PVD26896.1 - 0.062 12.1 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 PVD26897.1 - 7.2e-07 29.0 6.7 0.058 12.9 0.6 3.3 3 0 0 3 3 3 3 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 PVD26897.1 - 3e-06 27.2 1.6 1.2 9.0 0.0 3.6 3 0 0 3 3 3 3 TMEM154 protein family EphA2_TM PF14575.6 PVD26897.1 - 9.2e-05 23.2 2.4 3.7 8.5 0.0 4.3 4 0 0 4 4 3 1 Ephrin type-A receptor 2 transmembrane domain DUF3169 PF11368.8 PVD26897.1 - 0.00049 19.7 1.0 4.2 6.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3169) BatA PF07584.11 PVD26897.1 - 0.012 16.0 4.8 26 5.2 0.0 4.2 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal DUF5385 PF17359.2 PVD26897.1 - 0.031 13.9 2.1 14 5.2 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5385) YSIRK_signal PF04650.17 PVD26897.1 - 0.038 13.9 2.1 7.6 6.5 0.2 2.8 2 0 0 2 2 2 0 YSIRK type signal peptide DUF347 PF03988.12 PVD26897.1 - 0.053 13.7 5.9 12 6.2 0.2 3.5 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) DUF983 PF06170.12 PVD26897.1 - 0.054 13.9 2.5 53 4.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Adeno_E3_CR2 PF02439.15 PVD26897.1 - 0.059 13.1 24.6 1.2 8.9 0.5 3.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 PVD26897.1 - 0.064 13.5 0.1 68 3.8 0.0 3.5 3 0 0 3 3 3 0 Protein melan-A RIFIN PF02009.16 PVD26897.1 - 0.12 12.2 11.9 1.8 8.4 0.2 3.6 4 0 0 4 4 4 0 Rifin SmpA_OmlA PF04355.13 PVD26897.1 - 0.24 11.2 1.4 9.1 6.2 0.1 3.4 3 0 0 3 3 3 0 SmpA / OmlA family DUF4199 PF13858.6 PVD26897.1 - 0.41 11.0 5.2 21 5.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) EGF_3 PF12947.7 PVD26897.1 - 0.46 10.7 21.3 2.9 8.2 0.2 4.2 4 0 0 4 4 4 0 EGF domain ASFV_J13L PF05568.11 PVD26897.1 - 0.78 9.5 7.7 8.8 6.0 0.3 3.2 3 0 0 3 3 3 0 African swine fever virus J13L protein DUF3021 PF11457.8 PVD26897.1 - 2.5 8.4 8.0 10 6.5 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) FixQ PF05545.11 PVD26897.1 - 3.8 7.5 5.0 16 5.6 0.2 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ ApoC-I PF04691.12 PVD26897.1 - 6.8 6.7 6.6 5.8 6.9 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) EphA2_TM PF14575.6 PVD26899.1 - 0.004 18.0 0.0 2.2 9.2 0.1 2.9 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF1935 PF09149.10 PVD26899.1 - 0.0098 16.3 2.5 3.9 7.9 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1935) TMEM154 PF15102.6 PVD26899.1 - 0.014 15.3 0.2 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family 7TM_GPCR_Srv PF10323.9 PVD26899.1 - 0.019 14.3 2.2 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv BHD_1 PF10403.9 PVD26899.1 - 0.043 13.7 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 PapG_N PF03627.13 PVD26899.1 - 0.33 10.6 3.5 5.9 6.5 0.2 2.2 2 0 0 2 2 2 0 PapG carbohydrate binding domain Cadherin_C_2 PF16492.5 PVD26899.1 - 3.8 8.3 12.2 13 6.6 5.7 3.7 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal PMP1_2 PF08114.11 PVD26900.1 - 0.0043 16.7 0.1 0.0088 15.8 0.1 1.4 1 0 0 1 1 1 1 ATPase proteolipid family DUF4229 PF14012.6 PVD26900.1 - 0.02 15.0 0.5 0.038 14.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF5325 PF17259.2 PVD26900.1 - 0.033 14.0 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF4190 PF13828.6 PVD26900.1 - 0.087 12.6 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) GIDE PF12483.8 PVD26902.1 - 0.072 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase DUF4448 PF14610.6 PVD26904.1 - 0.0048 16.7 0.1 0.0064 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) MACPF PF01823.19 PVD26905.1 - 3.4e-15 56.7 0.0 5.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain PAN_4 PF14295.6 PVD26905.1 - 0.0003 20.7 1.4 0.00093 19.1 1.4 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PVD26905.1 - 0.0023 18.0 0.5 0.0023 18.0 0.5 2.1 2 0 0 2 2 2 1 PAN-like domain PAN_3 PF08277.12 PVD26905.1 - 0.21 11.4 5.2 0.083 12.7 0.6 2.6 3 0 0 3 3 3 0 PAN-like domain EB PF01683.18 PVD26905.1 - 0.85 10.0 16.5 0.058 13.7 8.4 3.2 2 1 1 3 3 3 0 EB module TMEM100 PF16311.5 PVD26906.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 DUF3112 PF11309.8 PVD26906.1 - 0.4 10.1 3.1 6.2 6.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) EphA2_TM PF14575.6 PVD26907.1 - 0.13 13.1 0.2 0.3 12.0 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4488 PF14869.6 PVD26908.1 - 9.5e-07 28.8 0.1 1.1 9.2 0.1 4.1 4 0 0 4 4 4 3 Domain of unknown function (DUF4488) Rax2 PF12768.7 PVD26908.1 - 3.5e-05 23.4 0.1 0.0011 18.5 0.0 2.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF749 PF05370.11 PVD26908.1 - 0.0072 16.4 0.2 0.82 9.8 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF749) Kunitz_legume PF00197.18 PVD26908.1 - 0.21 11.5 10.8 1.9 8.4 0.2 4.8 4 1 1 5 5 5 0 Trypsin and protease inhibitor LST1 PF05083.13 PVD26908.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 LST-1 protein PTS_2-RNA PF01885.16 PVD26909.1 - 0.083 12.9 0.0 8.1 6.5 0.0 2.3 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family EGF_3 PF12947.7 PVD26909.1 - 1.8 8.9 6.9 14 6.0 0.7 2.8 2 0 0 2 2 2 0 EGF domain BC10 PF06726.12 PVD26909.1 - 6.3 7.1 6.6 20 5.5 1.2 2.7 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 EphA2_TM PF14575.6 PVD26910.1 - 0.058 14.3 2.3 0.067 14.1 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3675 PF12428.8 PVD26910.1 - 0.36 11.4 1.4 8.4 7.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3675) Glycophorin_A PF01102.18 PVD26911.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.7 2 1 1 3 3 3 0 Glycophorin A DUF2757 PF10955.8 PVD26912.1 - 0.00011 22.4 0.1 0.84 9.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2757) APS-reductase_C PF12139.8 PVD26912.1 - 0.009 16.2 0.0 5.5 7.3 0.0 2.6 2 0 0 2 2 2 2 Adenosine-5'-phosphosulfate reductase beta subunit Cohesin PF00963.18 PVD26912.1 - 0.024 14.9 0.2 2.3 8.4 0.0 3.3 3 0 0 3 3 3 0 Cohesin domain LysR_substrate PF03466.20 PVD26912.1 - 0.028 13.8 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain DUF4834 PF16118.5 PVD26912.1 - 0.064 14.2 0.5 1.5 9.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4625 PF15418.6 PVD26912.1 - 0.07 13.4 1.3 4.3 7.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4625) Cadherin_5 PF17892.1 PVD26912.1 - 0.074 13.0 0.6 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Cadherin-like domain DUF2294 PF10057.9 PVD26912.1 - 0.098 12.8 0.6 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF3084 PF11283.8 PVD26912.1 - 0.33 11.0 5.6 1.4 9.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) MSG PF02349.15 PVD26912.1 - 3.5 7.9 11.5 10 6.4 1.3 3.2 3 0 0 3 3 3 0 Major surface glycoprotein Ribosomal_S13_N PF08069.12 PVD26913.1 - 0.8 9.8 4.8 18 5.5 0.2 2.9 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain Cornifin PF02389.15 PVD26913.1 - 4.8 7.4 18.2 7.7 6.7 5.6 3.4 2 1 1 3 3 3 0 Cornifin (SPRR) family RNA_pol_Rpc82 PF05645.13 PVD26914.1 - 5e-06 26.5 10.0 0.21 11.3 0.2 3.7 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 Glyco_hydro_65m PF03632.15 PVD26914.1 - 0.0067 15.3 2.5 1.4 7.7 0.1 3.1 3 0 0 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain DUF3377 PF11857.8 PVD26914.1 - 0.018 14.9 2.1 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Cyc-maltodext_N PF09087.11 PVD26914.1 - 0.78 10.1 5.1 39 4.6 0.1 4.4 4 0 0 4 4 4 0 Cyclomaltodextrinase, N-terminal TILa PF12714.7 PVD26914.1 - 2.8 7.9 11.8 23 5.0 0.4 3.5 3 0 0 3 3 3 0 TILa domain zf-C2H2 PF00096.26 PVD26915.1 - 8.3e-07 29.1 0.6 3.5e-06 27.2 0.6 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD26915.1 - 0.016 16.0 0.4 0.016 16.0 0.4 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD26915.1 - 0.077 13.5 7.7 0.49 10.9 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD26915.1 - 0.15 12.4 1.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SNF PF00209.18 PVD26916.1 - 2.8e-140 468.5 30.1 8.2e-132 440.5 26.5 2.3 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF5526 PF17664.1 PVD26917.1 - 8.1e-17 61.3 0.8 1.3e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5526) MRP-L27 PF09809.9 PVD26918.1 - 2e-22 79.2 0.1 2.9e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 JHY PF15261.6 PVD26919.1 - 1.3e-27 97.1 7.7 1.3e-27 97.1 7.7 3.4 4 0 0 4 4 4 1 Jhy protein Ig_3 PF13927.6 PVD26921.1 - 1.3e-62 208.3 9.4 6.7e-14 52.2 0.1 6.3 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD26921.1 - 5.8e-57 189.7 5.0 1.3e-09 38.0 0.1 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 PVD26921.1 - 9.7e-44 147.5 6.8 1.6e-07 31.4 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 PVD26921.1 - 4.4e-32 110.3 15.1 2.4e-09 37.4 0.0 8.0 6 3 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 PVD26921.1 - 7.7e-23 80.7 12.4 5.7e-05 23.3 0.0 8.1 6 2 1 8 8 8 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD26921.1 - 1.9e-10 40.6 1.3 0.16 12.1 0.0 4.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD26921.1 - 2.9e-10 40.0 0.7 4.7 7.3 0.0 6.5 6 0 0 6 6 6 3 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD26921.1 - 3.9e-07 29.5 1.6 0.44 10.1 0.0 5.2 6 0 0 6 6 6 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD26921.1 - 0.0023 17.9 0.8 2.3 8.3 0.0 4.0 4 1 0 4 4 4 1 C17orf99 Ig domain DUF5008 PF16400.5 PVD26921.1 - 0.12 12.5 0.0 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5008) Porphobil_deam PF01379.20 PVD26922.1 - 2.1e-73 246.2 0.0 3.5e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 PVD26922.1 - 8e-15 55.0 0.1 9e-14 51.6 0.1 2.6 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CCDC92 PF14916.6 PVD26922.1 - 0.063 13.0 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Prefoldin_2 PF01920.20 PVD26923.1 - 6.5e-28 96.8 1.5 8.3e-28 96.4 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.12 PVD26923.1 - 0.00017 21.6 2.2 0.0078 16.2 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Prefoldin PF02996.17 PVD26923.1 - 0.014 15.3 1.6 0.13 12.1 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit HDV_ag PF01517.18 PVD26923.1 - 0.028 14.2 2.1 0.028 14.2 2.1 1.7 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen OmpH PF03938.14 PVD26923.1 - 0.053 13.9 3.6 0.13 12.6 0.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF148 PF02520.17 PVD26923.1 - 0.062 13.4 1.5 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 pRN1_helical PF13010.6 PVD26923.1 - 0.074 13.0 0.6 0.15 12.0 0.4 1.6 2 0 0 2 2 2 0 Primase helical domain DegS PF05384.11 PVD26923.1 - 0.16 11.5 5.1 0.43 10.0 0.8 2.0 2 0 0 2 2 2 0 Sensor protein DegS Med9 PF07544.13 PVD26923.1 - 0.37 10.9 3.3 0.64 10.1 0.1 2.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Ig_3 PF13927.6 PVD26924.1 - 2.2e-11 44.2 1.4 0.00068 20.2 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 PVD26924.1 - 2.6e-11 43.7 1.2 0.0014 18.9 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 PVD26924.1 - 1.8e-10 40.8 0.3 0.0013 18.9 0.0 3.6 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD26924.1 - 3.2e-06 27.1 0.0 0.032 14.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD26924.1 - 5.1e-06 26.6 2.1 0.36 11.0 0.0 5.1 3 2 1 4 4 4 1 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD26924.1 - 0.082 12.5 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 PVD26925.1 - 2.7e-05 24.4 0.0 6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 PVD26925.1 - 9.1e-05 23.0 0.0 0.00016 22.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD26925.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD26925.1 - 0.027 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_6 PF18452.1 PVD26925.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 PVD26926.1 - 1.9e-27 95.6 3.4 1.3e-13 51.3 0.1 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD26926.1 - 2.3e-23 82.1 0.6 3.3e-11 43.1 0.2 3.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 PVD26926.1 - 3.5e-20 72.0 1.2 4.3e-10 39.6 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin domain fn3 PF00041.21 PVD26926.1 - 7.7e-19 67.8 7.6 9.8e-09 35.5 0.0 3.6 3 1 0 3 3 3 2 Fibronectin type III domain Ig_2 PF13895.6 PVD26926.1 - 6.8e-17 61.6 2.5 4e-08 33.5 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD26926.1 - 4.3e-06 26.7 0.1 0.0032 17.5 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set PF07686.17 PVD26926.1 - 5.8e-06 26.5 3.0 0.058 13.6 0.2 4.5 4 1 1 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD26926.1 - 0.00013 22.0 0.3 0.0015 18.6 0.1 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD26926.1 - 0.0002 21.9 10.5 0.83 10.3 0.0 3.4 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 PVD26926.1 - 0.00057 20.1 1.5 1.1 9.6 0.0 3.9 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 PVD26926.1 - 0.0036 17.3 0.1 3.5 7.7 0.0 3.0 3 0 0 3 3 3 2 C17orf99 Ig domain V-set_CD47 PF08204.11 PVD26926.1 - 0.0058 16.6 0.1 0.35 10.8 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain EccE PF11203.8 PVD26927.1 - 0.51 10.7 3.7 0.48 10.8 0.5 2.2 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PRIMA1 PF16101.5 PVD26930.1 - 0.17 11.9 10.3 0.2 11.7 10.3 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD26930.1 - 0.85 9.0 8.3 0.85 9.0 8.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD26930.1 - 1.4 9.0 6.0 1.4 9.0 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PALP PF00291.25 PVD26933.1 - 5.9e-61 206.4 0.0 8.4e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 PVD26933.1 - 2.6e-12 47.0 0.3 2.2e-08 34.4 0.1 3.1 3 0 0 3 3 3 2 CBS domain Methyltransf_12 PF08242.12 PVD26933.1 - 0.058 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 PVD26935.1 - 6.8e-13 48.9 12.4 0.00054 20.7 0.8 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26935.1 - 8.9e-10 38.7 0.1 0.013 15.8 0.0 4.4 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 PVD26935.1 - 0.0008 17.8 0.0 0.0014 17.0 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz BUD22 PF09073.10 PVD26935.1 - 0.25 10.6 7.4 0.35 10.1 7.4 1.1 1 0 0 1 1 1 0 BUD22 TMEM192 PF14802.6 PVD26936.1 - 2.1e-37 128.5 4.7 2.8e-37 128.1 4.7 1.1 1 0 0 1 1 1 1 TMEM192 family Y_phosphatase PF00102.27 PVD26938.1 - 3.7e-54 183.8 0.1 4.1e-30 105.1 0.1 2.8 3 0 0 3 3 3 2 Protein-tyrosine phosphatase EphA2_TM PF14575.6 PVD26938.1 - 0.0056 17.5 0.0 0.013 16.4 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 PVD26938.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 PVD26938.1 - 0.052 13.5 1.8 0.052 13.5 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family Pox_A14 PF05767.12 PVD26938.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3169 PF11368.8 PVD26938.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF443 PF04276.12 PVD26938.1 - 0.13 12.0 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Neur_chan_LBD PF02931.23 PVD26939.1 - 3.8e-49 167.0 6.9 5.5e-49 166.5 6.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD26939.1 - 2.7e-11 44.0 0.8 4.5e-11 43.3 0.8 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region BRAP2 PF07576.12 PVD26939.1 - 0.044 14.0 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 LIM_bind PF01803.16 PVD26939.1 - 0.083 12.4 0.7 0.66 9.5 0.2 2.0 2 0 0 2 2 2 0 LIM-domain binding protein Glyco_hydro_cc PF11790.8 PVD26940.1 - 0.019 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26941.1 - 1.2e-18 67.3 0.0 1.1e-15 57.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26941.1 - 2e-13 50.8 0.0 4.9e-12 46.3 0.0 3.0 4 0 0 4 4 4 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 PVD26941.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 PVD26942.1 - 2e-29 102.8 0.0 3.1e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 PVD26942.1 - 2e-11 44.3 0.6 2.6e-09 37.5 0.0 3.1 3 0 0 3 3 3 1 Carbohydrate binding domain Glyco_transf_21 PF13506.6 PVD26943.1 - 5.7e-49 165.9 0.0 8.3e-49 165.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 PVD26943.1 - 8e-20 71.7 0.0 1.2e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PVD26943.1 - 6.2e-10 39.3 0.7 1.1e-09 38.5 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Rax2 PF12768.7 PVD26943.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 PVD26943.1 - 0.031 14.2 1.1 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Cytadhesin_P30 PF07271.11 PVD26943.1 - 0.082 12.5 0.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytadhesin P30/P32 DUF5326 PF17260.2 PVD26943.1 - 9.7 6.4 8.9 40 4.5 0.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Ig_3 PF13927.6 PVD26944.1 - 0.0027 18.3 0.2 0.32 11.6 0.0 3.4 3 2 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD26944.1 - 0.0029 17.9 0.1 0.093 13.1 0.0 3.0 3 1 0 3 3 3 1 Immunoglobulin domain BAF PF02961.14 PVD26945.1 - 8e-27 93.5 4.1 8.3e-09 35.8 0.0 6.4 3 1 3 6 6 6 4 Barrier to autointegration factor V-set PF07686.17 PVD26945.1 - 7e-07 29.4 0.9 1.2 9.3 0.0 4.0 2 1 1 3 3 3 3 Immunoglobulin V-set domain I-set PF07679.16 PVD26945.1 - 5.7e-06 26.3 0.3 0.29 11.2 0.0 4.4 3 1 1 4 4 4 2 Immunoglobulin I-set domain ig PF00047.25 PVD26945.1 - 1.1e-05 25.5 5.2 0.041 14.1 0.1 4.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 PVD26945.1 - 8e-05 23.2 6.9 0.23 12.1 0.0 5.2 5 1 0 5 5 5 2 Immunoglobulin domain Ig_6 PF18452.1 PVD26945.1 - 0.0021 17.6 0.4 5 6.8 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain HHH_5 PF14520.6 PVD26945.1 - 0.029 15.0 0.0 0.4 11.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Izumo-Ig PF16706.5 PVD26945.1 - 0.065 13.3 0.1 5.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain IMS_HHH PF11798.8 PVD26945.1 - 0.15 12.5 0.0 0.55 10.7 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif Ig_4 PF16680.5 PVD26945.1 - 0.19 12.0 7.6 3.3 8.0 0.2 4.3 5 0 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain DUF4714 PF15833.5 PVD26946.1 - 0.057 13.4 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) TMEM154 PF15102.6 PVD26946.1 - 0.13 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 PVD26946.1 - 0.17 11.5 0.6 0.27 10.8 0.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.6 PVD26947.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family SIT PF15330.6 PVD26947.1 - 0.012 16.1 0.0 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DAG1 PF05454.11 PVD26947.1 - 0.039 13.3 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Cadherin_C_2 PF16492.5 PVD26947.1 - 0.14 12.9 2.0 0.9 10.3 0.1 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Ninjurin PF04923.12 PVD26947.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 2 0 0 2 2 2 0 Ninjurin Herpes_gE PF02480.16 PVD26949.1 - 0.00022 20.1 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 PVD26949.1 - 0.00046 20.1 1.5 0.27 11.1 0.0 2.8 3 0 0 3 3 3 2 TMEM154 protein family EphA2_TM PF14575.6 PVD26949.1 - 0.00073 20.4 5.5 0.44 11.5 0.0 3.1 3 1 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 PVD26949.1 - 0.0054 16.5 0.7 0.93 9.4 0.1 2.8 3 0 0 3 3 3 1 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 PVD26949.1 - 0.0076 16.2 0.1 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 Protocadherin MFS_2 PF13347.6 PVD26949.1 - 0.051 12.1 0.0 0.26 9.8 0.0 1.8 2 0 0 2 2 2 0 MFS/sugar transport protein DUF347 PF03988.12 PVD26949.1 - 0.078 13.2 1.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF5305 PF17231.2 PVD26949.1 - 0.11 11.9 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4381 PF14316.6 PVD26949.1 - 0.14 12.4 0.0 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4245 PF14030.6 PVD26949.1 - 0.23 11.4 2.0 6.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) DUF4051 PF13260.6 PVD26949.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Ig_2 PF13895.6 PVD26950.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Calcyon PF06387.11 PVD26950.1 - 0.04 13.9 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Ig_3 PF13927.6 PVD26950.1 - 0.066 13.8 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF3789 PF12664.7 PVD26950.1 - 1.5 8.6 6.3 1.5 8.6 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) RabGAP-TBC PF00566.18 PVD26951.1 - 2.8e-27 95.8 0.8 5.1e-27 94.9 0.8 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 PVD26951.1 - 0.0002 21.8 0.0 0.0012 19.3 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain Myosin_TH1 PF06017.13 PVD26951.1 - 0.00073 19.3 0.2 0.0021 17.8 0.0 1.8 1 1 1 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding DCA16 PF15349.6 PVD26951.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Cbl_N PF02262.16 PVD26952.1 - 7.5e-56 187.5 0.7 9.5e-56 187.2 0.7 1.1 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N2 PF02761.14 PVD26952.1 - 0.0061 17.3 0.8 0.016 15.9 0.3 2.0 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 PVD26953.1 - 3.3e-46 155.1 0.0 5.6e-46 154.3 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 PVD26953.1 - 2.4e-29 101.9 0.3 4.6e-29 101.0 0.3 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 PVD26953.1 - 1.5e-12 47.2 8.1 1.5e-12 47.2 8.1 2.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PVD26953.1 - 9.2e-11 41.4 7.6 9.2e-11 41.4 7.6 2.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD26953.1 - 7.8e-09 35.3 7.0 7.8e-09 35.3 7.0 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD26953.1 - 3e-07 30.7 7.9 3e-07 30.7 7.9 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD26953.1 - 2e-05 24.3 8.1 8.4e-05 22.3 8.1 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA PF00627.31 PVD26953.1 - 2.1e-05 24.3 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_UBOX PF13445.6 PVD26953.1 - 0.00099 19.1 6.0 0.00099 19.1 6.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD26953.1 - 0.003 17.5 9.9 0.003 17.5 9.9 2.4 3 0 0 3 3 1 1 zinc-RING finger domain SH2 PF00017.24 PVD26953.1 - 0.022 14.9 0.0 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 SH2 domain zf-rbx1 PF12678.7 PVD26953.1 - 0.06 13.6 7.1 0.16 12.2 7.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain UBA_3 PF09288.10 PVD26953.1 - 0.22 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain WD40 PF00400.32 PVD26954.1 - 3.6e-15 56.1 3.7 0.13 13.2 0.0 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD26954.1 - 7.6e-05 22.9 0.0 4.5 7.6 0.0 5.9 6 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 PVD26954.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 HELP motif Ig_3 PF13927.6 PVD26955.1 - 1.1e-07 32.3 0.8 8.5e-05 23.1 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD26955.1 - 0.041 14.0 0.6 4.8 7.4 0.1 2.8 2 1 0 2 2 2 0 Immunoglobulin domain Pkinase_Tyr PF07714.17 PVD26956.1 - 1.9e-49 168.3 0.1 8.9e-38 130.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 PVD26956.1 - 2.2e-36 120.7 21.2 0.00094 19.2 0.1 12.7 13 0 0 13 13 12 9 HEAT repeat HEAT_2 PF13646.6 PVD26956.1 - 1.3e-33 115.3 2.6 1.9e-13 50.6 0.0 6.1 3 1 2 5 5 5 5 HEAT repeats Pkinase PF00069.25 PVD26956.1 - 6.1e-21 75.0 0.0 2e-13 50.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 PVD26956.1 - 1.8e-20 73.3 3.2 3.3e-07 30.8 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD26956.1 - 1.3e-19 70.1 0.1 3.3e-10 39.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD26956.1 - 1.4e-16 60.5 4.8 5.9e-07 29.6 0.2 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD26956.1 - 2.7e-11 43.7 2.1 0.0016 18.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Vac14_Fab1_bd PF12755.7 PVD26956.1 - 5e-09 36.6 0.7 0.51 11.0 0.0 6.0 5 2 3 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 PVD26956.1 - 3e-08 34.0 3.0 0.19 12.3 0.1 6.7 6 1 1 7 7 6 2 HEAT-like repeat V-set PF07686.17 PVD26956.1 - 4.1e-08 33.4 1.1 0.0027 17.8 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain CLASP_N PF12348.8 PVD26956.1 - 6.3e-05 22.7 0.6 0.54 9.8 0.0 4.4 2 2 2 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 PVD26956.1 - 9.1e-05 22.5 4.3 0.058 13.4 0.2 3.7 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Ig_4 PF16680.5 PVD26956.1 - 0.0054 17.0 0.1 3.1 8.1 0.0 3.6 4 0 0 4 4 3 1 T-cell surface glycoprotein CD3 delta chain TAF6_C PF07571.13 PVD26956.1 - 0.0091 16.3 0.0 6.8 7.1 0.0 4.2 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain DUF3091 PF11291.8 PVD26956.1 - 0.15 12.2 0.0 0.77 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) Adeno_E3_CR1 PF02440.15 PVD26956.1 - 0.17 11.7 0.1 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 HLH PF00010.26 PVD26959.1 - 2.6e-12 46.5 0.3 5.7e-12 45.4 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MID_pPIWI_RE PF18157.1 PVD26959.1 - 1.3 9.3 5.2 3 8.1 0.1 2.6 1 1 1 2 2 2 0 MID domain of pPIWI_RE Presenilin PF01080.17 PVD26959.1 - 2.5 6.8 5.3 3.1 6.5 5.3 1.2 1 0 0 1 1 1 0 Presenilin EspB_PE PF18625.1 PVD26959.1 - 3.8 8.0 7.4 0.69 10.4 0.2 2.9 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain Ig_2 PF13895.6 PVD26960.1 - 1.6e-05 25.2 5.9 0.067 13.5 0.2 4.1 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 PVD26960.1 - 0.00014 22.0 0.6 0.7 10.1 0.1 3.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 PVD26960.1 - 0.00027 21.5 9.4 0.027 15.1 0.0 5.0 5 0 0 5 5 5 1 Immunoglobulin domain TMEM51 PF15345.6 PVD26960.1 - 0.0072 16.2 1.1 0.013 15.3 1.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Orf78 PF06024.12 PVD26960.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Ig_3 PF13927.6 PVD26961.1 - 0.0098 16.5 0.2 0.035 14.7 0.1 2.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 PVD26961.1 - 0.038 14.1 0.6 0.2 11.8 0.1 2.1 1 1 1 2 2 2 0 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD26961.1 - 0.3 11.4 2.2 4.7 7.6 0.5 3.0 1 1 1 2 2 2 0 Immunoglobulin domain IL3Ra_N PF18611.1 PVD26961.1 - 6.5 6.8 6.4 0.78 9.8 1.5 2.0 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain zf-C3HC4_3 PF13920.6 PVD26962.1 - 7.2e-09 35.4 10.5 1.5e-08 34.4 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD26962.1 - 1.3e-08 35.0 13.6 1.3e-08 35.0 13.6 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD26962.1 - 5.1e-08 32.7 13.2 1.2e-07 31.5 13.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD26962.1 - 1.7e-07 31.0 14.0 1.7e-07 31.0 14.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD26962.1 - 1.2e-06 28.4 11.5 1.2e-06 28.4 11.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD26962.1 - 1.6e-06 28.2 13.5 3.9e-06 26.9 13.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD26962.1 - 0.00012 22.0 11.8 0.00032 20.6 11.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD26962.1 - 0.00044 20.5 11.4 0.00044 20.5 11.4 2.3 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PVD26962.1 - 0.012 15.7 8.4 0.024 14.7 7.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PVD26962.1 - 0.15 11.8 7.4 0.38 10.6 7.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 PVD26962.1 - 0.16 11.9 16.0 1.1 9.1 15.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD26962.1 - 0.59 10.0 13.1 0.18 11.7 9.5 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 PVD26962.1 - 0.76 9.9 9.7 3.2 7.8 9.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2517 PF10725.9 PVD26962.1 - 1.4 8.7 3.6 0.99 9.2 0.2 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF2517) Zn_ribbon_17 PF17120.5 PVD26962.1 - 1.5 8.5 9.0 5.3 6.7 9.0 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYVE PF01363.21 PVD26962.1 - 1.5 9.0 8.0 4.1 7.6 8.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 PVD26962.1 - 7.1 6.9 11.2 1.9 8.8 5.7 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FANCL_C PF11793.8 PVD26962.1 - 8.4 6.6 10.0 31 4.8 8.2 2.5 2 0 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.8 PVD26962.1 - 8.8 6.2 8.1 16 5.4 8.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 PVD26964.1 - 1.2e-50 172.4 0.0 1.6e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD26964.1 - 2.2e-22 79.6 0.0 3.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 PVD26964.1 - 0.079 12.5 1.3 0.26 10.8 0.1 2.2 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF908 PF06012.12 PVD26964.1 - 1.4 8.2 8.1 2 7.7 2.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) APOBEC3 PF18771.1 PVD26965.1 - 2.2e-11 44.0 0.3 5.1e-11 42.8 0.2 1.6 1 1 1 2 2 2 1 APOBEC3 NAD1 PF18778.1 PVD26965.1 - 7e-11 42.5 0.2 5.8e-10 39.5 0.2 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 PVD26965.1 - 5.9e-10 39.3 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 PVD26965.1 - 8.7e-09 35.5 0.1 1e-07 32.1 0.1 2.1 1 1 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4 PF18775.1 PVD26965.1 - 3.4e-08 33.5 0.0 6.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 APOBEC4 APOBEC2 PF18772.1 PVD26965.1 - 1.2e-07 31.9 0.1 4.2e-07 30.2 0.2 1.7 2 0 0 2 2 2 1 APOBEC2 APOBEC4_like PF18774.1 PVD26965.1 - 2.7e-06 27.3 0.1 2e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 PVD26965.1 - 0.00015 21.9 0.1 0.00051 20.2 0.1 1.8 2 0 0 2 2 2 1 APOBEC1 NAD2 PF18782.1 PVD26965.1 - 0.00016 21.9 0.1 0.00024 21.2 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 dCMP_cyt_deam_1 PF00383.23 PVD26965.1 - 0.00079 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.6 PVD26965.1 - 0.0019 18.3 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase AID PF18767.1 PVD26965.1 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Activation induced deaminase Toxin-deaminase PF14424.6 PVD26965.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases BLACT_WH PF17778.1 PVD26965.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain APOBEC_N PF08210.11 PVD26966.1 - 3.1e-11 43.5 0.1 5.8e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 PVD26966.1 - 2.4e-10 40.8 0.3 9.1e-10 38.9 0.3 1.8 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 PVD26966.1 - 1e-09 38.7 0.1 1.9e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 PVD26966.1 - 6.7e-09 35.9 0.1 2e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4 PF18775.1 PVD26966.1 - 1.5e-08 34.7 0.1 3.8e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 APOBEC4 APOBEC2 PF18772.1 PVD26966.1 - 1.1e-07 32.1 0.2 2.4e-07 31.0 0.2 1.5 2 0 0 2 2 2 1 APOBEC2 dCMP_cyt_deam_1 PF00383.23 PVD26966.1 - 5.9e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC4_like PF18774.1 PVD26966.1 - 6e-06 26.2 0.1 4.5e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 PVD26966.1 - 1.1e-05 25.6 0.1 2.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 APOBEC1 NAD2 PF18782.1 PVD26966.1 - 1.1e-05 25.6 0.1 1.8e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 XOO_2897-deam PF14440.6 PVD26966.1 - 0.00036 20.6 0.5 0.0027 17.8 0.1 2.3 2 0 0 2 2 2 1 Xanthomonas XOO_2897-like deaminase MafB19-deam PF14437.6 PVD26966.1 - 0.034 13.9 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 MafB19-like deaminase eIF3m_C_helix PF18005.1 PVD26966.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix FYVE_2 PF02318.16 PVD26966.1 - 0.64 10.2 10.9 0.1 12.8 1.8 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger APOBEC_N PF08210.11 PVD26967.1 - 2.1e-34 119.0 1.3 2.3e-14 53.7 0.2 4.0 2 2 2 4 4 4 3 APOBEC-like N-terminal domain APOBEC3 PF18771.1 PVD26967.1 - 2.3e-33 115.2 6.4 5.4e-11 42.8 0.6 4.3 4 0 0 4 4 4 3 APOBEC3 NAD1 PF18778.1 PVD26967.1 - 5.2e-33 114.6 7.7 4.3e-11 43.2 1.0 4.2 4 1 0 4 4 4 3 Novel AID APOBEC clade 1 SNAD4 PF18750.1 PVD26967.1 - 2.5e-29 101.7 4.3 3.4e-09 36.8 0.1 4.1 4 0 0 4 4 4 3 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 PVD26967.1 - 2.4e-28 99.4 1.5 4.8e-09 36.5 0.2 3.6 4 0 0 4 4 4 3 APOBEC2 APOBEC4 PF18775.1 PVD26967.1 - 8.6e-24 83.5 2.0 1.4e-07 31.5 0.0 4.5 4 0 0 4 4 4 3 APOBEC4 APOBEC4_like PF18774.1 PVD26967.1 - 5.6e-19 68.4 1.8 2.9e-06 27.2 0.2 3.6 3 0 0 3 3 3 3 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 PVD26967.1 - 9.1e-19 68.2 1.6 2.2e-06 27.9 0.1 3.3 3 0 0 3 3 3 3 Novel AID APOBEC clade 2 APOBEC1 PF18769.1 PVD26967.1 - 1.8e-18 66.7 0.3 9.4e-05 22.6 0.0 4.0 4 0 0 4 4 4 3 APOBEC1 dCMP_cyt_deam_1 PF00383.23 PVD26967.1 - 3.2e-11 43.0 0.0 0.0072 16.2 0.0 3.3 3 0 0 3 3 3 3 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.6 PVD26967.1 - 5.2e-06 26.6 1.4 0.4 10.8 0.1 3.3 3 0 0 3 3 3 2 The BURPS668_1122 family of deaminases AID PF18767.1 PVD26967.1 - 5.4e-06 26.3 0.6 0.88 9.6 0.0 3.5 3 0 0 3 3 3 2 Activation induced deaminase FANCI_HD1 PF14679.6 PVD26967.1 - 0.008 16.1 0.6 0.77 9.8 0.2 2.7 2 0 0 2 2 2 1 FANCI helical domain 1 MafB19-deam PF14437.6 PVD26967.1 - 0.074 12.8 0.0 31 4.3 0.0 3.1 3 0 0 3 3 3 0 MafB19-like deaminase RBD PF02196.15 PVD26967.1 - 0.2 11.8 0.5 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Raf-like Ras-binding domain APOBEC3 PF18771.1 PVD26968.1 - 2.9e-11 43.6 0.1 4.9e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 APOBEC3 NAD1 PF18778.1 PVD26968.1 - 1.5e-10 41.5 0.9 3.2e-10 40.4 0.3 1.8 1 1 1 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 PVD26968.1 - 2.7e-10 40.4 0.2 4.3e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC4 PF18775.1 PVD26968.1 - 1.3e-08 34.8 0.1 3.1e-08 33.7 0.1 1.6 1 1 0 1 1 1 1 APOBEC4 SNAD4 PF18750.1 PVD26968.1 - 1.8e-08 34.5 1.3 4.2e-08 33.3 0.2 2.1 1 1 1 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 PVD26968.1 - 2.7e-07 30.8 0.2 6.6e-07 29.5 0.2 1.7 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 PVD26968.1 - 3.2e-05 24.1 0.2 5.4e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC1 PF18769.1 PVD26968.1 - 3.3e-05 24.1 2.0 0.00041 20.6 0.1 2.8 2 1 1 3 3 3 1 APOBEC1 APOBEC4_like PF18774.1 PVD26968.1 - 6e-05 23.0 1.3 0.00059 19.8 0.1 2.7 2 2 1 3 3 3 1 APOBEC4-like -AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 PVD26968.1 - 0.0028 17.5 0.1 0.0052 16.6 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1923 PF09083.10 PVD26968.1 - 0.096 12.4 0.7 51 3.7 0.0 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF1923) Toxin-deaminase PF14424.6 PVD26968.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases AID PF18767.1 PVD26968.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Activation induced deaminase AbiJ_NTD5 PF18865.1 PVD26968.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 APOBEC_N PF08210.11 PVD26969.1 - 1.6e-21 77.0 2.6 5.7e-11 42.6 0.3 2.3 2 0 0 2 2 2 2 APOBEC-like N-terminal domain NAD1 PF18778.1 PVD26969.1 - 2.8e-21 76.4 7.0 2e-10 41.0 1.5 3.5 2 2 0 2 2 2 2 Novel AID APOBEC clade 1 APOBEC4 PF18775.1 PVD26969.1 - 1.2e-20 73.4 4.0 3.4e-10 39.9 1.5 2.5 2 0 0 2 2 2 2 APOBEC4 APOBEC2 PF18772.1 PVD26969.1 - 6.2e-16 58.9 6.5 1e-06 28.9 2.4 3.5 2 2 1 3 3 3 2 APOBEC2 SNAD4 PF18750.1 PVD26969.1 - 1.5e-15 57.3 6.9 2.5e-07 30.8 1.5 3.4 2 2 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 PVD26969.1 - 4e-14 52.9 4.6 1.1e-06 28.8 0.1 2.3 2 0 0 2 2 2 2 APOBEC3 APOBEC4_like PF18774.1 PVD26969.1 - 4.2e-09 36.4 4.7 0.00018 21.4 0.7 4.2 2 2 0 2 2 2 2 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 PVD26969.1 - 1e-08 35.3 3.7 0.002 18.4 0.3 3.2 3 0 0 3 3 3 2 APOBEC1 NAD2 PF18782.1 PVD26969.1 - 1.4e-08 35.0 1.4 0.0015 18.7 0.6 2.2 2 0 0 2 2 2 2 Novel AID APOBEC clade 2 dCMP_cyt_deam_1 PF00383.23 PVD26969.1 - 0.0002 21.2 0.5 0.12 12.3 0.1 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.6 PVD26969.1 - 0.00021 21.4 1.1 0.036 14.2 0.4 2.6 2 0 0 2 2 2 1 The BURPS668_1122 family of deaminases AID PF18767.1 PVD26969.1 - 0.00023 21.1 2.2 0.2 11.7 0.0 3.1 4 0 0 4 4 4 2 Activation induced deaminase MafB19-deam PF14437.6 PVD26969.1 - 0.014 15.2 0.8 0.036 13.8 0.2 1.9 2 0 0 2 2 2 0 MafB19-like deaminase CAML PF14963.6 PVD26969.1 - 2.8 8.0 4.9 5.4 7.1 4.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand APOBEC_N PF08210.11 PVD26970.1 - 1.2e-22 80.7 1.9 1.6e-10 41.1 0.0 3.1 2 1 1 3 3 3 2 APOBEC-like N-terminal domain APOBEC4 PF18775.1 PVD26970.1 - 1.4e-21 76.4 5.0 6.8e-11 42.2 0.1 3.4 2 2 0 2 2 2 2 APOBEC4 NAD1 PF18778.1 PVD26970.1 - 4.7e-19 69.1 7.3 4.3e-08 33.4 0.1 4.3 1 1 2 3 3 3 2 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 PVD26970.1 - 5.6e-18 65.4 1.4 7.6e-10 39.0 0.1 2.6 2 0 0 2 2 2 2 APOBEC3 APOBEC2 PF18772.1 PVD26970.1 - 1.1e-17 64.7 1.9 1e-07 32.2 0.0 3.8 2 1 2 4 4 4 2 APOBEC2 SNAD4 PF18750.1 PVD26970.1 - 1.7e-16 60.4 3.0 2.1e-07 31.1 0.0 3.8 2 2 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 XOO_2897-deam PF14440.6 PVD26970.1 - 4.2e-12 46.0 0.6 6.7e-06 26.1 0.0 3.1 3 0 0 3 3 3 2 Xanthomonas XOO_2897-like deaminase APOBEC4_like PF18774.1 PVD26970.1 - 1e-09 38.4 0.6 8.3e-05 22.5 0.0 3.9 2 2 0 2 2 2 2 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 PVD26970.1 - 2.2e-09 37.7 0.6 0.0003 20.9 0.0 3.0 2 1 0 2 2 2 2 Novel AID APOBEC clade 2 APOBEC1 PF18769.1 PVD26970.1 - 3.3e-06 27.3 5.7 0.086 13.1 0.0 4.3 5 1 0 5 5 4 2 APOBEC1 dCMP_cyt_deam_1 PF00383.23 PVD26970.1 - 3.4e-06 26.9 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.6 PVD26970.1 - 2.3e-05 24.5 1.7 0.17 11.9 0.0 2.9 3 0 0 3 3 3 2 The BURPS668_1122 family of deaminases AID PF18767.1 PVD26970.1 - 0.00018 21.4 0.4 0.39 10.8 0.0 3.3 3 0 0 3 3 3 2 Activation induced deaminase RIF5_SNase_1 PF18187.1 PVD26970.1 - 0.054 13.2 0.0 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 TbRIF5 SNase domain 1 OTT_1508_deam PF14441.6 PVD26970.1 - 0.13 12.3 2.6 0.5 10.4 0.4 2.4 2 0 0 2 2 2 0 OTT_1508-like deaminase APOBEC4 PF18775.1 PVD26971.1 - 0.065 13.4 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 DHHC PF01529.20 PVD26972.1 - 1.3e-19 70.6 12.4 1.3e-19 70.6 12.4 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase UFC1 PF08694.11 PVD26973.1 - 1.4e-87 291.1 0.1 1.6e-87 290.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SLATT_5 PF18160.1 PVD26973.1 - 0.057 12.7 0.2 0.074 12.4 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Sel1 PF08238.12 PVD26974.1 - 4.8e-12 46.1 19.5 0.0018 18.9 0.2 7.7 8 0 0 8 8 8 5 Sel1 repeat Laminin_G_3 PF13385.6 PVD26974.1 - 2.9e-05 24.3 0.0 7.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Asp PF00026.23 PVD26975.1 - 1.8e-35 122.9 1.0 1.5e-14 54.2 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.6 PVD26975.1 - 1.3e-07 31.5 0.4 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PVD26975.1 - 4e-06 27.2 0.4 5.9e-05 23.4 0.0 2.7 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal LapA_dom PF06305.11 PVD26975.1 - 0.078 12.8 0.3 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 PVD26976.1 - 0.0015 19.4 0.1 0.0044 17.9 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SPR1 PF15356.6 PVD26977.1 - 0.032 14.7 1.1 0.042 14.4 1.1 1.3 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 FAM70 PF14967.6 PVD26977.1 - 0.15 11.5 1.7 0.18 11.3 1.7 1.2 1 0 0 1 1 1 0 FAM70 protein DUF1699 PF08004.11 PVD26978.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Ig_4 PF16680.5 PVD26979.1 - 0.049 13.9 1.5 0.065 13.5 0.1 1.9 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Mid2 PF04478.12 PVD26980.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 PVD26980.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family ArAE_2 PF10334.9 PVD26982.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 RVT_1 PF00078.27 PVD26983.1 - 6.5e-18 65.1 0.0 8.3e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 PVD26984.1 - 0.1 12.8 0.6 0.2 11.8 0.6 1.5 1 0 0 1 1 1 0 Immunoglobulin V-set domain TRAP_alpha PF03896.16 PVD26984.1 - 5.9 6.0 5.7 4.3 6.4 3.0 2.0 2 1 1 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit V-set PF07686.17 PVD26985.1 - 0.032 14.4 2.1 0.19 11.9 0.1 2.7 2 1 0 3 3 3 0 Immunoglobulin V-set domain ig PF00047.25 PVD26985.1 - 0.24 11.6 0.2 0.24 11.6 0.2 3.2 4 0 0 4 4 4 0 Immunoglobulin domain Ig_3 PF13927.6 PVD26985.1 - 0.45 11.1 4.1 3.3 8.4 0.0 3.2 2 1 1 3 3 3 0 Immunoglobulin domain Shisa PF13908.6 PVD26986.1 - 0.00012 22.4 3.4 0.12 12.6 0.8 2.3 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 PVD26986.1 - 0.011 16.6 2.9 0.83 10.6 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.17 PVD26986.1 - 0.028 14.6 0.1 0.063 13.4 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin V-set domain Vpu PF00558.19 PVD26986.1 - 0.035 13.9 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 0 Vpu protein HemY_N PF07219.13 PVD26986.1 - 0.07 13.3 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus EII-GUT PF03608.13 PVD26986.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Chordopox_A13L PF05961.11 PVD26986.1 - 0.36 11.1 0.1 0.36 11.1 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Vpu PF00558.19 PVD26987.1 - 0.0078 16.0 0.0 0.0078 16.0 0.0 2.9 3 0 0 3 3 3 1 Vpu protein EphA2_TM PF14575.6 PVD26987.1 - 0.014 16.2 2.7 0.39 11.6 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 PVD26987.1 - 0.024 14.9 0.0 0.024 14.9 0.0 2.5 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Ribosomal_60s PF00428.19 PVD26987.1 - 0.082 13.5 1.1 0.22 12.1 1.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Orthoreo_P10 PF07204.11 PVD26987.1 - 1 9.4 3.8 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 PRIMA1 PF16101.5 PVD26987.1 - 1.2 9.1 4.5 1.6 8.8 0.1 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 PVD26988.1 - 2.5e-07 31.5 1.1 6e-05 23.8 0.2 2.9 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 PVD26988.1 - 0.0011 17.9 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Amnionless Kunitz_legume PF00197.18 PVD26988.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin and protease inhibitor PRIMA1 PF16101.5 PVD26988.1 - 0.0021 18.1 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 Protocadherin PF08374.11 PVD26988.1 - 0.0024 17.9 0.2 0.1 12.6 0.0 2.2 2 0 0 2 2 2 1 Protocadherin Orthopox_A36R PF05950.11 PVD26988.1 - 0.027 14.6 2.2 0.87 9.7 0.1 2.5 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Phage_holin_3_6 PF07332.11 PVD26988.1 - 0.08 13.0 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MARVEL PF01284.23 PVD26988.1 - 0.11 12.6 3.8 0.17 11.9 0.1 2.5 2 1 1 3 3 3 0 Membrane-associating domain BaxI_1 PF12811.7 PVD26988.1 - 0.15 11.6 1.5 7.8 6.0 0.1 2.4 2 1 0 2 2 2 0 Bax inhibitor 1 like PDGLE PF13190.6 PVD26988.1 - 0.22 11.4 0.1 0.92 9.4 0.1 2.1 2 0 0 2 2 2 0 PDGLE domain DUF4131 PF13567.6 PVD26988.1 - 0.68 9.6 2.1 3.2 7.4 0.7 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) S1FA PF04689.13 PVD26988.1 - 1 9.6 0.0 1 9.6 0.0 2.3 3 0 0 3 3 3 0 DNA binding protein S1FA DUF4083 PF13314.6 PVD26988.1 - 5.7 7.0 7.1 30 4.6 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Ig_3 PF13927.6 PVD26989.1 - 3.3e-06 27.6 5.6 0.032 14.8 0.1 4.6 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD26989.1 - 1.6e-05 25.0 6.5 0.14 12.3 0.3 4.5 3 1 0 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 PVD26989.1 - 0.00043 20.3 0.2 0.56 10.3 0.2 3.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD26989.1 - 0.038 14.2 10.2 0.19 11.9 0.2 5.1 5 1 0 5 5 5 0 Immunoglobulin domain DUF3091 PF11291.8 PVD26989.1 - 0.042 14.0 2.3 8.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3091) Ig_2 PF13895.6 PVD26989.1 - 0.38 11.1 8.1 16 5.9 0.5 4.7 3 2 0 3 3 3 0 Immunoglobulin domain Marek_A PF02124.15 PVD26990.1 - 0.047 13.5 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A V-set PF07686.17 PVD26990.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain DUF1213 PF06740.12 PVD26990.1 - 1.3 9.7 4.7 2.7 8.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) CRR7 PF12095.8 PVD26992.1 - 0.18 12.3 0.3 0.56 10.7 0.3 1.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 fn3 PF00041.21 PVD26993.1 - 2.2e-07 31.1 0.2 3.8e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III domain AI-2E_transport PF01594.16 PVD26993.1 - 0.00019 20.7 0.2 0.00024 20.3 0.2 1.1 1 0 0 1 1 1 1 AI-2E family transporter DUF4448 PF14610.6 PVD26993.1 - 0.015 15.1 0.2 0.031 14.0 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Tissue_fac PF01108.17 PVD26993.1 - 0.062 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Tissue factor SKG6 PF08693.10 PVD26993.1 - 0.33 10.4 5.1 0.59 9.6 5.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sortilin-Vps10 PF15902.5 PVD26994.1 - 1.4e-99 333.9 0.7 2.2e-99 333.3 0.7 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Ldl_recept_a PF00057.18 PVD26994.1 - 1.5e-85 281.1 178.3 6.3e-13 48.7 11.5 11.2 11 0 0 11 11 11 9 Low-density lipoprotein receptor domain class A Sortilin_C PF15901.5 PVD26994.1 - 9.2e-33 114.0 0.1 9.2e-33 114.0 0.1 5.5 2 1 4 6 6 6 1 Sortilin, neurotensin receptor 3, C-terminal fn3 PF00041.21 PVD26994.1 - 9.9e-15 54.7 5.4 0.00054 20.2 0.1 5.0 3 1 1 4 4 4 4 Fibronectin type III domain Ldl_recept_b PF00058.17 PVD26994.1 - 1.4e-08 35.1 0.1 0.00011 22.6 0.0 4.5 4 0 0 4 4 4 1 Low-density lipoprotein receptor repeat class B BNR PF02012.20 PVD26994.1 - 0.00011 21.6 11.3 2.1 8.7 0.1 5.5 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_6 PF15899.5 PVD26994.1 - 0.0051 16.8 2.9 2.7 8.3 0.1 4.0 3 0 0 3 3 3 1 BNR-Asp box repeat SusE PF14292.6 PVD26994.1 - 3.8 7.8 5.3 22 5.4 0.2 3.8 3 1 1 4 4 4 0 SusE outer membrane protein DUF2053 PF09767.9 PVD26995.1 - 5.1e-41 140.5 0.9 5.1e-41 140.5 0.9 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) WD40 PF00400.32 PVD26996.1 - 3.1e-15 56.3 6.5 0.0043 17.9 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF5074 PF16819.5 PVD26996.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) HSL_N PF06350.12 PVD26997.1 - 7e-111 370.1 0.4 1.1e-110 369.5 0.4 1.3 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 PVD26997.1 - 5.4e-40 137.5 0.0 4.9e-30 105.0 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PVD26997.1 - 3.1e-07 29.6 0.0 6.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Ras PF00071.22 PVD26998.1 - 4.7e-26 91.3 0.1 7.7e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD26998.1 - 9.2e-11 42.0 0.0 2.6e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase XRN_N PF03159.18 PVD26998.1 - 0.024 14.1 0.2 0.34 10.3 0.2 2.1 1 1 1 2 2 2 0 XRN 5'-3' exonuclease N-terminus UCH PF00443.29 PVD27001.1 - 3.7e-72 242.9 0.1 5.2e-72 242.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD27001.1 - 5.5e-18 65.6 2.0 3.3e-17 63.1 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Whib PF02467.16 PVD27001.1 - 0.37 11.4 3.8 0.15 12.7 1.0 1.8 2 0 0 2 2 2 0 Transcription factor WhiB LRR_8 PF13855.6 PVD27002.1 - 3.8e-78 257.2 85.5 8.7e-15 54.2 2.4 7.0 3 2 6 9 9 9 8 Leucine rich repeat LRR_5 PF13306.6 PVD27002.1 - 2.8e-34 117.8 1.7 1.1e-09 38.4 0.0 4.3 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD27002.1 - 6.6e-33 112.2 53.6 5e-06 26.8 2.7 8.7 5 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD27002.1 - 4.1e-16 59.0 21.6 0.00011 21.7 1.5 5.3 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 PVD27002.1 - 9.1e-10 37.7 45.9 0.054 14.1 1.2 13.4 13 1 0 13 13 13 4 Leucine Rich Repeat fn3 PF00041.21 PVD27002.1 - 7.3e-08 32.7 0.9 1.9e-07 31.3 0.9 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD27002.1 - 0.0018 18.8 0.9 0.014 16.0 0.3 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain LRRNT PF01462.18 PVD27002.1 - 0.079 12.6 2.4 0.21 11.3 0.9 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PVD27002.1 - 0.086 12.9 46.6 1.8 8.9 0.5 10.5 11 0 0 11 11 11 0 Leucine Rich repeat NosD PF05048.13 PVD27002.1 - 0.95 8.7 5.2 0.54 9.5 0.6 2.2 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) TRAM_LAG1_CLN8 PF03798.16 PVD27003.1 - 2.6e-08 33.8 8.7 3.6e-08 33.4 8.7 1.2 1 0 0 1 1 1 1 TLC domain DUF4131 PF13567.6 PVD27003.1 - 0.0013 18.5 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) RIIa PF02197.17 PVD27004.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit 7tm_1 PF00001.21 PVD27006.1 - 6.5e-62 209.2 0.0 1.1e-61 208.5 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD27006.1 - 3.7e-12 46.2 10.5 4.1e-06 26.4 3.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD27006.1 - 3.4e-06 26.9 6.7 3.4e-06 26.9 6.7 2.2 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD27006.1 - 0.00025 20.9 4.8 0.04 13.7 2.0 2.5 2 1 1 3 3 3 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 PVD27006.1 - 0.0012 18.4 3.6 0.0012 18.4 3.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF996 PF06195.13 PVD27006.1 - 0.0015 18.8 6.8 0.0082 16.4 3.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF996) Saf_2TM PF18303.1 PVD27006.1 - 0.0016 18.0 0.1 0.0047 16.5 0.2 1.6 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain DUF418 PF04235.12 PVD27006.1 - 0.025 14.5 0.2 8 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DUF2207 PF09972.9 PVD27006.1 - 0.027 13.2 4.5 0.15 10.8 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Macoilin PF09726.9 PVD27006.1 - 1.2 7.6 4.2 1.7 7.1 4.2 1.2 1 0 0 1 1 1 0 Macoilin family OTU PF02338.19 PVD27008.1 - 2.2e-09 37.9 0.0 4.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease EFG_IV PF03764.18 PVD27008.1 - 1.6e-05 24.7 0.0 49 3.7 0.0 6.4 1 1 8 9 9 9 0 Elongation factor G, domain IV Peptidase_C65 PF10275.9 PVD27008.1 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase C65 Otubain T4bSS_IcmS PF12608.8 PVD27008.1 - 0.075 13.3 0.4 3.8 7.9 0.0 3.9 2 1 1 5 5 5 0 Type IVb secretion, IcmS, effector-recruitment Mesd PF10185.9 PVD27008.1 - 0.11 12.5 8.9 11 5.9 0.1 5.9 2 1 7 9 9 9 0 Chaperone for wingless signalling and trafficking of LDL receptor Gypsy PF07253.11 PVD27008.1 - 0.23 9.9 7.8 52 2.2 0.1 4.3 1 1 8 9 9 9 0 Gypsy protein RNase_H PF00075.24 PVD27009.1 - 1.9e-12 47.6 0.0 5.4e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 RNase H PLU-1 PF08429.11 PVD27010.1 - 0.0017 17.6 0.2 0.0026 17.0 0.2 1.2 1 0 0 1 1 1 1 PLU-1-like protein IFT46_B_C PF12317.8 PVD27010.1 - 0.087 12.5 3.3 0.14 11.9 1.5 1.9 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Exo_endo_phos_2 PF14529.6 PVD27011.1 - 0.00089 19.1 0.7 0.0052 16.6 0.0 2.3 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase Protamine_P2 PF00841.19 PVD27011.1 - 0.048 14.2 8.4 0.082 13.4 8.4 1.4 1 0 0 1 1 1 0 Sperm histone P2 YfcL PF08891.11 PVD27011.1 - 0.1 13.0 0.3 0.23 11.9 0.3 1.6 1 1 0 1 1 1 0 YfcL protein RVT_1 PF00078.27 PVD27013.1 - 1.4e-17 64.0 0.1 1.5e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3268 PF11672.8 PVD27013.1 - 0.077 13.3 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain EMI PF07546.13 PVD27015.1 - 5.6 7.8 7.4 19 6.1 0.8 2.8 3 0 0 3 3 3 0 EMI domain RVT_1 PF00078.27 PVD27017.1 - 3.8e-12 46.2 0.0 4.2e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OTU PF02338.19 PVD27018.1 - 1.1e-08 35.6 0.4 2.6e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PVD27018.1 - 0.02 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase C65 Otubain Tetraspanin PF00335.20 PVD27019.1 - 5.5e-33 114.6 14.2 7.6e-33 114.1 14.2 1.2 1 0 0 1 1 1 1 Tetraspanin family XPC-binding PF09280.11 PVD27020.1 - 0.11 12.2 1.0 0.32 10.7 1.0 1.8 1 0 0 1 1 1 0 XPC-binding domain 7tm_2 PF00002.24 PVD27021.1 - 4.6e-26 91.6 14.0 6e-26 91.2 14.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EI24 PF07264.11 PVD27022.1 - 2.1e-13 50.9 14.7 3.6e-13 50.1 14.7 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribosomal_S25 PF03297.15 PVD27023.1 - 4.7e-28 97.4 10.0 8.2e-28 96.6 10.0 1.4 1 1 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 PVD27023.1 - 0.00015 21.8 0.2 0.00024 21.2 0.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 PVD27023.1 - 0.003 17.4 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 PVD27023.1 - 0.025 14.4 0.3 0.036 13.9 0.3 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MORN PF02493.20 PVD27024.1 - 3e-39 130.6 48.4 1.1e-07 31.4 0.4 7.5 7 0 0 7 7 7 7 MORN repeat DUF3048_C PF17479.2 PVD27024.1 - 0.2 12.0 9.7 1.3 9.4 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain ABC_membrane PF00664.23 PVD27025.1 - 4.3e-54 184.0 17.3 2.7e-41 142.1 13.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27025.1 - 1.7e-48 164.6 0.1 4e-24 85.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27025.1 - 1.7e-10 40.7 4.3 0.00049 19.6 0.1 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27025.1 - 6.1e-07 30.0 0.1 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27025.1 - 3.5e-06 27.1 0.4 0.094 12.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27025.1 - 1.8e-05 24.7 0.4 0.07 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 PVD27025.1 - 0.00017 21.9 0.6 1.1 9.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PVD27025.1 - 0.00023 20.8 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 PVD27025.1 - 0.00059 19.5 0.2 0.027 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 PVD27025.1 - 0.00062 20.3 0.6 1 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 PVD27025.1 - 0.00081 19.3 0.3 1.9 8.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 PVD27025.1 - 0.0024 17.0 0.0 0.72 8.9 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 PVD27025.1 - 0.0032 16.8 0.0 0.37 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 PVD27025.1 - 0.0052 16.0 0.1 0.76 8.9 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 PVD27025.1 - 0.0053 16.6 0.2 0.085 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PVD27025.1 - 0.006 15.8 0.6 2.5 7.2 0.0 2.6 3 0 0 3 3 3 2 NB-ARC domain Dynamin_N PF00350.23 PVD27025.1 - 0.01 15.9 1.6 0.21 11.7 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 PVD27025.1 - 0.011 15.5 1.7 3.8 7.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 PVD27025.1 - 0.012 15.3 0.4 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 PVD27025.1 - 0.013 14.4 0.2 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 PVD27025.1 - 0.022 14.5 0.6 11 5.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 PVD27025.1 - 0.028 13.9 0.1 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 PVD27025.1 - 0.067 13.6 0.2 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 PVD27025.1 - 0.081 11.8 0.0 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_24 PF13479.6 PVD27025.1 - 0.099 12.4 0.2 5 6.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PVD27025.1 - 0.1 12.8 0.1 4.5 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PVD27025.1 - 0.11 12.9 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 PVD27025.1 - 0.59 10.1 2.9 35 4.4 0.0 3.8 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 PVD27025.1 - 0.88 9.6 7.0 2 8.4 0.5 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain VCBS PF13517.6 PVD27026.1 - 2.5e-12 47.2 1.0 5.6e-07 30.1 0.7 2.7 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PVD27026.1 - 1.9e-07 31.1 0.3 0.0032 17.5 0.4 3.2 3 0 0 3 3 3 2 FG-GAP repeat PliI PF16743.5 PVD27026.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Periplasmic lysozyme inhibitor of I-type lysozyme TcdB_toxin_midN PF12256.8 PVD27026.1 - 0.064 12.6 0.0 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.6 PVD27026.1 - 0.24 11.0 2.6 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 EF hand Homeodomain PF00046.29 PVD27027.1 - 3.4e-16 58.8 0.5 4.7e-16 58.4 0.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD27027.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Tetraspanin PF00335.20 PVD27028.1 - 3.7e-14 53.0 6.9 2.3e-12 47.1 3.5 2.1 1 1 1 2 2 2 2 Tetraspanin family Pox_A14 PF05767.12 PVD27028.1 - 0.39 10.9 3.9 0.84 9.8 3.9 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Myelin-PO_C PF10570.9 PVD27029.1 - 0.015 15.7 0.5 5.2 7.6 0.0 2.7 2 1 0 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region Ig_2 PF13895.6 PVD27030.1 - 2e-05 24.8 0.7 2e-05 24.8 0.7 4.6 6 0 0 6 6 6 2 Immunoglobulin domain Ig_3 PF13927.6 PVD27030.1 - 3.7e-05 24.2 15.7 0.00015 22.3 0.8 4.5 5 0 0 5 5 5 2 Immunoglobulin domain I-set PF07679.16 PVD27030.1 - 0.00011 22.2 0.2 0.0095 16.0 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin I-set domain MAP17 PF15807.5 PVD27030.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 V-set PF07686.17 PVD27030.1 - 3.6 7.8 8.9 35 4.6 0.1 5.0 6 0 0 6 6 6 0 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD27031.1 - 4.8e-08 33.5 13.8 3.2e-07 30.8 0.2 5.0 5 0 0 5 5 5 1 Immunoglobulin domain I-set PF07679.16 PVD27031.1 - 8.3e-07 29.0 0.7 0.00011 22.1 0.2 3.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD27031.1 - 4.2e-06 26.7 2.5 0.11 12.5 0.4 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 PVD27031.1 - 8.7e-05 22.8 0.6 8.7e-05 22.8 0.6 4.8 4 1 1 5 5 5 1 Immunoglobulin domain Imm57 PF15596.6 PVD27031.1 - 0.056 13.8 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Immunity protein 57 I-set PF07679.16 PVD27032.1 - 3.2e-06 27.1 2.4 6.9e-05 22.8 0.2 4.2 4 1 0 4 4 4 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27032.1 - 3.9e-06 27.4 0.6 3.9e-06 27.4 0.6 5.3 4 0 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27032.1 - 1e-05 25.8 0.3 1e-05 25.8 0.3 5.0 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 PVD27032.1 - 9.1e-05 22.6 4.6 0.00082 19.5 0.5 4.2 2 1 1 3 3 3 1 Immunoglobulin domain EphA2_TM PF14575.6 PVD27032.1 - 0.00038 21.3 0.0 1.6 9.7 0.0 2.9 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 PVD27032.1 - 0.0004 19.3 0.0 0.62 8.8 0.0 2.4 2 1 0 2 2 2 2 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 PVD27032.1 - 0.0013 18.6 4.1 0.027 14.4 0.0 3.8 4 0 0 4 4 3 1 TMEM154 protein family Baculo_11_kDa PF06143.11 PVD27032.1 - 0.0075 15.8 0.3 0.66 9.6 0.1 2.4 2 0 0 2 2 2 1 Baculovirus 11 kDa family ECSCR PF15820.5 PVD27032.1 - 0.0089 15.8 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator Ig_5 PF16681.5 PVD27032.1 - 0.01 16.2 1.5 0.074 13.5 0.1 3.1 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF4064 PF13273.6 PVD27032.1 - 0.025 14.9 0.2 5.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) PET PF06297.14 PVD27032.1 - 0.032 14.5 0.0 13 6.2 0.0 3.5 4 0 0 4 4 4 0 PET Domain Orf78 PF06024.12 PVD27032.1 - 0.037 14.3 1.9 2.2 8.7 0.0 3.6 4 0 0 4 4 4 0 Orf78 (ac78) DUF3377 PF11857.8 PVD27032.1 - 0.1 12.5 2.5 0.75 9.8 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) C2-set_2 PF08205.12 PVD27032.1 - 0.14 12.3 12.6 0.2 11.7 0.4 3.5 4 0 0 4 4 2 0 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD27032.1 - 0.22 11.6 0.6 1.9 8.6 0.0 2.9 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain VMA21 PF09446.10 PVD27032.1 - 7.2 6.8 8.2 12 6.1 0.8 3.0 3 0 0 3 3 3 0 VMA21-like domain Ig_3 PF13927.6 PVD27033.1 - 7.6e-11 42.5 24.3 7.5e-08 32.9 0.5 6.2 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 PVD27033.1 - 4.2e-07 29.9 15.3 0.016 15.3 0.4 5.1 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 PVD27033.1 - 5.2e-07 29.9 0.3 5.2e-07 29.9 0.3 6.0 6 2 0 6 6 6 2 Immunoglobulin domain I-set PF07679.16 PVD27033.1 - 7.5e-07 29.1 3.9 2.7e-05 24.2 0.3 3.9 3 1 0 3 3 3 1 Immunoglobulin I-set domain Self-incomp_S1 PF05938.11 PVD27033.1 - 0.00063 20.3 0.2 11 6.6 0.0 4.2 4 0 0 4 4 4 2 Plant self-incompatibility protein S1 ig PF00047.25 PVD27033.1 - 0.0056 16.8 0.6 0.0056 16.8 0.6 7.4 7 2 0 7 7 7 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27034.1 - 3.8e-10 40.2 8.6 5.4e-09 36.5 0.9 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD27034.1 - 3.5e-09 36.6 2.7 2.2e-07 30.8 0.8 3.3 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27034.1 - 1.5e-07 31.6 0.8 1.5e-07 31.6 0.8 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD27034.1 - 8.3e-06 25.9 6.9 2.4e-05 24.4 0.9 3.9 4 1 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27034.1 - 0.00014 21.8 8.1 0.01 15.8 0.3 3.2 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27034.1 - 0.57 10.4 6.5 8.8 6.5 0.1 3.7 3 1 1 4 4 4 0 Immunoglobulin V-set domain ICAM_N PF03921.14 PVD27034.1 - 0.72 9.6 4.4 0.17 11.6 0.4 2.1 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain I-set PF07679.16 PVD27036.1 - 0.041 14.0 1.3 4.8 7.3 0.0 3.3 2 1 1 3 3 3 0 Immunoglobulin I-set domain NFACT-C PF11923.8 PVD27036.1 - 0.061 13.2 0.1 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 NFACT protein C-terminal domain DUF2510 PF10708.9 PVD27036.1 - 0.2 11.4 0.5 14 5.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Presenilin PF01080.17 PVD27040.1 - 0.18 10.5 10.9 0.22 10.2 10.9 1.1 1 0 0 1 1 1 0 Presenilin SspB PF04386.13 PVD27040.1 - 0.59 10.0 18.7 0.29 11.0 5.4 2.0 2 0 0 2 2 2 0 Stringent starvation protein B DUF4834 PF16118.5 PVD27040.1 - 1.7 9.7 9.8 5.5 8.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CobT PF06213.12 PVD27040.1 - 1.8 7.9 28.1 0.54 9.6 8.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 PVD27040.1 - 2.4 6.9 16.2 2.9 6.6 16.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 PVD27040.1 - 3.8 6.4 8.4 4.6 6.2 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 PVD27040.1 - 7.9 6.4 10.1 0.42 10.6 0.3 2.0 1 1 1 2 2 2 0 Protein Family FAM60A SoxG PF04268.12 PVD27041.1 - 0.05 13.8 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family zf-C2H2_4 PF13894.6 PVD27042.1 - 0.006 17.3 3.0 1.2 10.2 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Myc_N PF01056.18 PVD27042.1 - 0.017 15.1 1.0 0.021 14.8 1.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 PVD27042.1 - 0.041 12.2 2.5 0.049 11.9 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-trcl PF13451.6 PVD27042.1 - 0.088 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C2H2 PF00096.26 PVD27042.1 - 0.092 13.2 2.6 10 6.8 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sporozoite_P67 PF05642.11 PVD27042.1 - 0.099 10.7 5.2 0.13 10.4 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 PVD27042.1 - 0.13 11.6 6.4 0.17 11.3 6.4 1.1 1 0 0 1 1 1 0 SDA1 zf-H2C2_2 PF13465.6 PVD27042.1 - 0.16 12.5 6.0 0.24 11.9 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain RNA_pol_Rpc4 PF05132.14 PVD27042.1 - 0.17 12.3 0.7 0.33 11.4 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zn_ribbon_SprT PF17283.2 PVD27042.1 - 0.4 10.6 2.9 11 6.1 0.0 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Nop14 PF04147.12 PVD27042.1 - 0.46 8.6 8.6 0.55 8.4 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 PVD27042.1 - 0.79 10.1 9.5 5.2 7.5 10.8 1.8 2 0 0 2 2 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 PVD27042.1 - 0.94 9.3 7.9 3.6 7.4 8.9 1.4 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 PVD27042.1 - 1.3 9.1 7.1 1.9 8.5 7.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 PVD27042.1 - 2.6 7.7 7.1 5.3 6.7 7.1 1.4 1 0 0 1 1 1 0 FAM176 family Ig_3 PF13927.6 PVD27043.1 - 2.9e-06 27.8 0.9 0.039 14.6 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD27043.1 - 6e-06 26.4 2.5 0.041 14.1 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 PVD27043.1 - 0.00067 19.8 1.7 2.8 8.2 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27043.1 - 0.0019 18.5 0.3 0.22 11.9 0.0 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ribosomal_L10 PF00466.20 PVD27044.1 - 0.051 13.7 0.6 0.12 12.5 0.6 1.7 1 0 0 1 1 1 0 Ribosomal protein L10 RelE PF06296.12 PVD27044.1 - 0.28 11.3 1.9 0.62 10.2 1.9 1.5 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system AAA_23 PF13476.6 PVD27044.1 - 7.2 7.1 9.4 9.8 6.6 9.4 1.2 1 0 0 1 1 1 0 AAA domain OATP PF03137.20 PVD27046.1 - 1.8e-102 343.4 13.3 1.2e-58 198.8 0.4 2.4 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 PVD27046.1 - 3.4e-08 33.5 11.4 3.4e-08 33.5 11.4 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain MFS_1 PF07690.16 PVD27046.1 - 2.6e-06 26.6 25.2 0.00089 18.3 3.3 4.1 4 1 0 4 4 4 3 Major Facilitator Superfamily Kazal_1 PF00050.21 PVD27046.1 - 0.011 15.7 6.1 0.011 15.7 6.1 1.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Phage_holin_3_6 PF07332.11 PVD27046.1 - 6.6 6.8 7.8 2.7 8.1 0.0 3.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III OATP PF03137.20 PVD27047.1 - 7.4e-30 103.7 0.2 9.6e-30 103.4 0.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD27047.1 - 1.9e-05 23.8 1.1 0.0027 16.7 0.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 PVD27047.1 - 0.07 13.4 0.2 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) OATP PF03137.20 PVD27048.1 - 5.2e-06 25.0 0.1 8.1e-06 24.4 0.1 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OATP PF03137.20 PVD27049.1 - 2.4e-10 39.4 0.6 9.6e-10 37.4 0.2 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2371 PF10177.9 PVD27049.1 - 0.056 13.6 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) OATP PF03137.20 PVD27050.1 - 1e-132 443.2 19.5 1.5e-132 442.7 19.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD27050.1 - 1.1e-17 64.0 37.6 2.6e-12 46.3 12.3 3.4 3 1 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD27050.1 - 3.7e-07 30.2 11.6 3.7e-07 30.2 11.6 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD27050.1 - 0.24 11.4 13.7 0.04 13.9 9.1 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF2834 PF11196.8 PVD27050.1 - 2.1 8.7 5.9 20 5.6 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) OATP PF03137.20 PVD27051.1 - 1.9e-123 412.7 21.9 2.6e-123 412.2 21.9 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD27051.1 - 1.4e-19 70.2 26.8 3.1e-13 49.4 9.5 3.5 3 1 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD27051.1 - 5.7e-07 29.6 9.6 5.7e-07 29.6 9.6 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD27051.1 - 0.00099 19.1 4.7 0.00099 19.1 4.7 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain LapA_dom PF06305.11 PVD27051.1 - 0.027 14.3 0.4 0.75 9.7 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 7tm_7 PF08395.12 PVD27052.1 - 5.8e-16 58.7 13.4 5.8e-16 58.7 13.4 1.4 1 1 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 PVD27052.1 - 2.9e-11 42.6 9.2 2.9e-11 42.6 9.2 1.3 1 1 0 1 1 1 1 Trehalose receptor 7tm_6 PF02949.20 PVD27052.1 - 7.4e-05 22.0 9.6 7.4e-05 22.0 9.6 1.5 1 1 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.12 PVD27053.1 - 0.00022 20.5 15.4 0.00047 19.5 15.3 1.4 1 1 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 PVD27053.1 - 0.039 12.6 7.3 0.034 12.8 6.0 1.4 1 1 0 1 1 1 0 Trehalose receptor DUF2207 PF09972.9 PVD27053.1 - 1.8 7.3 2.9 3.3 6.4 3.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CD20 PF04103.15 PVD27054.1 - 6.5e-07 29.6 2.0 9e-07 29.1 2.0 1.2 1 0 0 1 1 1 1 CD20-like family Podoplanin PF05808.11 PVD27055.1 - 0.24 11.5 0.4 20 5.3 0.3 2.7 2 1 0 2 2 2 0 Podoplanin Met_10 PF02475.16 PVD27055.1 - 0.26 11.0 1.1 0.39 10.4 1.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MIF PF01187.18 PVD27056.1 - 3.7e-21 75.6 0.0 4.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 PVD27056.1 - 0.014 15.3 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme CFAP91 PF14738.6 PVD27057.1 - 2.5e-63 212.7 10.9 2.5e-63 212.7 10.9 3.6 2 1 1 3 3 3 1 Cilia- and flagella-associated protein 91 DUF5624 PF18538.1 PVD27057.1 - 0.061 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Meis_PKNOX_N PF16493.5 PVD27058.1 - 1.3e-31 108.8 0.9 2.2e-31 108.0 0.9 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 PVD27058.1 - 1.1e-18 66.8 1.8 2.1e-18 65.9 1.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD27058.1 - 2e-07 30.7 0.4 3.9e-07 29.8 0.4 1.4 1 0 0 1 1 1 1 Homeodomain Complex1_49kDa PF00346.19 PVD27059.1 - 1.4e-107 358.9 0.0 5.4e-104 347.1 0.0 2.3 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 PVD27059.1 - 0.0022 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase BAG PF02179.16 PVD27060.1 - 4.8e-08 33.3 3.3 9.7e-08 32.3 3.3 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 PVD27060.1 - 1.1e-05 25.0 0.0 3.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family 4HB_MCP_1 PF12729.7 PVD27060.1 - 0.0024 17.4 4.6 0.0041 16.7 4.6 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Ubiquitin_5 PF18037.1 PVD27060.1 - 0.005 17.2 0.8 0.012 15.9 0.0 2.0 3 0 0 3 3 2 1 Ubiquitin-like domain Mod_r PF07200.13 PVD27060.1 - 0.0076 16.4 11.0 0.013 15.6 11.0 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 PVD27060.1 - 0.021 13.4 0.5 0.026 13.1 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBK1_ULD PF18396.1 PVD27060.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RSS_P20 PF11757.8 PVD27060.1 - 0.059 13.8 1.9 0.12 12.8 1.9 1.5 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain PilJ PF13675.6 PVD27060.1 - 0.1 12.6 0.6 0.18 11.8 0.2 1.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SKA2 PF16740.5 PVD27060.1 - 0.23 11.3 11.1 0.093 12.5 3.3 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 PVD27060.1 - 0.23 11.2 7.7 0.52 10.1 7.7 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SpecificRecomb PF10136.9 PVD27060.1 - 0.26 9.6 0.7 0.34 9.2 0.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase GLTP PF08718.11 PVD27060.1 - 0.3 11.3 1.6 1.9 8.8 1.6 2.2 2 1 0 2 2 2 0 Glycolipid transfer protein (GLTP) COG2 PF06148.11 PVD27060.1 - 0.67 10.0 5.7 0.48 10.5 1.6 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 PVD27060.1 - 1.3 7.8 11.5 3.4 6.5 9.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 PVD27060.1 - 2.3 8.7 9.6 2.4 8.7 2.0 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.17 PVD27060.1 - 3 7.8 9.3 6.3 6.7 0.4 3.3 1 1 2 3 3 3 0 Prefoldin subunit BST2 PF16716.5 PVD27060.1 - 6.3 7.5 13.4 7.4 7.2 4.6 3.2 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 CUB PF00431.20 PVD27061.1 - 1.9e-08 34.6 0.2 2.3e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 PVD27062.1 - 0.0015 18.8 0.0 0.0088 16.4 0.0 1.9 2 0 0 2 2 2 1 CUB domain CUB PF00431.20 PVD27063.1 - 0.0068 16.7 0.1 0.0096 16.3 0.1 1.4 1 1 0 1 1 1 1 CUB domain CRF-BP PF05428.11 PVD27063.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) NYN_YacP PF05991.11 PVD27063.1 - 0.15 11.9 0.0 11 5.9 0.0 2.1 1 1 1 2 2 2 0 YacP-like NYN domain adh_short PF00106.25 PVD27065.1 - 4.1e-35 121.0 0.0 5.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD27065.1 - 3.6e-18 66.0 0.0 5.4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD27065.1 - 5.6e-08 32.9 0.0 9.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD27065.1 - 0.0051 16.2 0.0 0.013 14.8 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) FOXP-CC PF16159.5 PVD27066.1 - 6e-05 23.6 16.5 0.054 14.1 0.2 5.0 4 1 1 5 5 5 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 PVD27066.1 - 0.00022 21.5 0.2 0.00022 21.5 0.2 4.4 4 1 0 4 4 4 1 Zinc-finger double domain zf-RING_7 PF02591.15 PVD27066.1 - 0.026 14.7 0.1 4 7.7 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain Prim_Zn_Ribbon PF08273.12 PVD27066.1 - 0.047 14.0 2.9 3.9 7.8 0.5 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C2H2_4 PF13894.6 PVD27066.1 - 0.6 11.1 24.4 0.81 10.7 0.5 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 PVD27066.1 - 1.8 8.7 14.6 1.6 8.8 6.2 2.7 2 1 0 2 2 2 0 Aberrant zinc-finger zf-UBP PF02148.19 PVD27066.1 - 4.4 7.7 20.9 5.9 7.3 3.9 4.0 2 2 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein COMPASS-Shg1 PF05205.12 PVD27067.1 - 0.063 14.0 0.1 0.11 13.2 0.1 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 OrsD PF12013.8 PVD27068.1 - 0.035 14.6 2.9 0.21 12.1 0.3 2.9 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_7 PF15269.6 PVD27068.1 - 0.042 13.9 5.6 1.5 9.0 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger zf-H2C2_5 PF13909.6 PVD27068.1 - 0.059 13.1 11.3 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD27068.1 - 0.63 10.6 12.8 5.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 PVD27068.1 - 0.86 9.3 5.9 5.1 6.8 3.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain BTB_2 PF02214.22 PVD27069.1 - 1.4e-15 57.4 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PVD27069.1 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Ank_5 PF13857.6 PVD27071.1 - 1.2e-28 98.8 9.4 7.3e-08 32.5 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27071.1 - 7.4e-22 77.7 4.8 2.7e-07 31.1 0.0 5.0 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27071.1 - 1.6e-21 75.7 7.7 0.0032 17.8 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 PVD27071.1 - 4.2e-21 75.0 7.2 0.00054 20.5 0.0 6.0 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD27071.1 - 8.3e-20 68.8 5.1 0.00067 19.9 0.0 8.6 10 0 0 10 10 10 4 Ankyrin repeat Propep_M14 PF02244.16 PVD27071.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Ank_5 PF13857.6 PVD27072.1 - 1.4e-21 76.3 3.4 7e-08 32.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27072.1 - 3.4e-18 66.0 0.9 0.00013 22.4 0.0 4.6 3 3 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD27072.1 - 2.1e-17 63.2 1.1 0.00028 21.4 0.0 5.2 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD27072.1 - 7.4e-17 61.0 1.2 0.023 15.1 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 PVD27072.1 - 1.1e-15 56.2 0.3 0.00065 20.0 0.0 7.5 9 0 0 9 9 9 3 Ankyrin repeat Propep_M14 PF02244.16 PVD27072.1 - 0.013 15.9 0.1 0.05 14.0 0.1 1.9 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Ank_5 PF13857.6 PVD27073.1 - 1.1e-25 89.4 11.8 9.4e-06 25.8 0.4 6.5 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD27073.1 - 4.3e-19 68.6 14.3 1.3e-05 25.7 0.0 8.0 4 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27073.1 - 1.5e-18 67.1 7.9 1.2e-06 29.1 0.4 5.1 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD27073.1 - 1.8e-15 55.5 8.5 0.39 11.4 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 PVD27073.1 - 1.4e-08 34.8 10.5 2.2 8.9 0.0 8.3 8 1 1 9 9 9 2 Ankyrin repeat RAP1 PF07218.11 PVD27074.1 - 0.012 13.9 0.3 0.013 13.8 0.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ank_5 PF13857.6 PVD27075.1 - 2.1e-25 88.4 22.0 2.2e-06 27.8 0.4 7.1 6 2 0 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD27075.1 - 2.5e-22 76.6 16.4 6e-05 23.1 0.0 10.0 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 PVD27075.1 - 4.2e-22 77.6 23.4 0.00011 22.4 0.1 9.6 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 PVD27075.1 - 8.1e-22 77.3 16.5 4e-06 27.3 0.1 8.0 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27075.1 - 5.6e-21 74.9 20.1 6.9e-06 26.6 3.9 5.7 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) DUF5535 PF17687.1 PVD27075.1 - 0.16 12.1 0.1 7.2 6.8 0.0 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5535) Ank_4 PF13637.6 PVD27076.1 - 1.8e-20 73.0 7.2 6.8e-05 23.4 0.0 6.0 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27076.1 - 4.2e-18 65.2 8.1 0.00024 21.3 0.1 5.0 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD27076.1 - 3.6e-17 62.0 6.9 0.0062 16.9 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 PVD27076.1 - 4.8e-17 60.3 5.3 0.0017 18.7 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 PVD27076.1 - 5.9e-17 62.0 6.6 0.00034 21.1 0.4 4.4 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Peptidase_M16 PF00675.20 PVD27076.1 - 0.025 14.6 0.0 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF3456 PF11938.8 PVD27076.1 - 0.039 14.5 0.2 0.072 13.6 0.2 1.4 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DSHCT PF08148.12 PVD27076.1 - 0.11 12.2 0.3 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 DSHCT (NUC185) domain Ank_4 PF13637.6 PVD27077.1 - 2.8e-17 62.8 9.1 2.5e-06 27.9 0.1 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27077.1 - 2.7e-14 53.5 13.7 5.7e-06 26.8 1.9 5.1 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD27077.1 - 3.7e-13 48.4 11.7 0.34 11.6 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD27077.1 - 2.4e-12 46.8 13.5 0.00012 22.3 0.4 5.6 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD27077.1 - 4.6e-12 45.8 19.9 0.00064 20.1 0.6 7.0 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD27078.1 - 1.6e-23 82.4 15.8 5.6e-08 32.9 0.4 5.2 4 2 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD27078.1 - 1.9e-23 82.5 18.5 9.8e-07 29.2 0.1 7.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD27078.1 - 1.7e-22 78.8 21.7 2e-05 24.8 0.1 8.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_2 PF12796.7 PVD27078.1 - 1.3e-20 73.8 12.8 1.5e-08 35.1 3.7 3.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD27078.1 - 1e-19 68.5 14.5 1.8e-05 24.8 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat DUF4865 PF16157.5 PVD27078.1 - 0.1 12.6 0.2 2.6 8.0 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4865) Ank_5 PF13857.6 PVD27079.1 - 4.3e-13 49.2 2.0 0.00045 20.5 0.1 5.9 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD27079.1 - 1.6e-11 44.5 7.1 0.3 11.7 0.0 7.1 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27079.1 - 2e-11 44.3 6.0 0.002 18.7 0.1 5.7 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27079.1 - 2.6e-09 37.1 3.3 0.57 10.7 0.0 7.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 PVD27079.1 - 6.9e-08 32.2 4.7 1.5 9.6 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat FAA_hydrolase_N PF09298.11 PVD27079.1 - 0.044 14.0 0.6 8.9 6.6 0.2 2.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal dUTPase PF00692.19 PVD27079.1 - 0.064 13.0 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 dUTPase Ank_4 PF13637.6 PVD27080.1 - 4.6e-65 215.2 40.2 1.5e-05 25.5 0.0 17.2 6 4 15 21 21 21 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27080.1 - 2.6e-58 194.5 48.4 8e-06 26.4 0.6 14.4 5 4 9 14 14 14 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD27080.1 - 1.7e-48 162.0 44.2 2.8e-05 24.3 0.2 16.3 14 4 2 16 16 16 12 Ankyrin repeats (many copies) Ank PF00023.30 PVD27080.1 - 1.1e-43 145.8 30.6 0.049 14.1 0.0 21.8 23 1 0 23 23 23 11 Ankyrin repeat Ank_3 PF13606.6 PVD27080.1 - 9.5e-40 130.1 31.8 0.17 12.6 0.0 22.0 26 0 0 26 26 24 10 Ankyrin repeat Transcrip_reg PF01709.20 PVD27080.1 - 4.8e-09 36.0 2.5 0.0025 17.3 0.0 3.5 4 0 0 4 4 4 2 Transcriptional regulator AGA2 PF17366.2 PVD27080.1 - 2.3e-05 24.0 0.9 0.23 11.2 0.1 2.6 2 0 0 2 2 2 2 A-agglutinin-binding subunit Aga2 Peptidase_S3 PF00944.19 PVD27080.1 - 0.0084 15.9 4.1 1.3 8.9 0.4 2.5 2 0 0 2 2 2 2 Alphavirus core protein Copper-bind PF00127.20 PVD27080.1 - 0.042 14.3 0.5 19 5.8 0.0 3.5 3 0 0 3 3 3 0 Copper binding proteins, plastocyanin/azurin family PPR PF01535.20 PVD27080.1 - 0.079 13.2 4.6 34 5.0 0.1 5.8 6 0 0 6 6 6 0 PPR repeat PPR_3 PF13812.6 PVD27080.1 - 0.082 13.0 0.0 1.5e+02 2.5 0.0 4.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF2408 PF10303.9 PVD27080.1 - 0.11 13.0 2.3 18 5.9 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2313 PF10076.9 PVD27080.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) ubiquitin PF00240.23 PVD27080.1 - 0.21 11.3 1.3 33 4.3 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin family EGF_3 PF12947.7 PVD27080.1 - 0.24 11.7 5.5 11 6.3 0.2 3.6 3 0 0 3 3 3 0 EGF domain PPR_2 PF13041.6 PVD27080.1 - 0.5 10.6 3.5 63 3.9 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family pRN1_helical PF13010.6 PVD27080.1 - 6 6.8 10.7 0.19 11.7 0.2 3.9 7 0 0 7 7 6 0 Primase helical domain DUF725 PF05267.12 PVD27080.1 - 6 6.9 11.8 6.4 6.8 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Ank_2 PF12796.7 PVD27081.1 - 4.6e-25 88.0 8.3 3.3e-06 27.6 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD27081.1 - 1.4e-23 83.0 8.4 2.5e-05 24.7 0.6 7.3 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27081.1 - 1e-22 79.9 12.6 1.2e-05 25.5 0.1 7.5 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD27081.1 - 1.1e-17 62.3 10.6 0.051 14.1 0.0 9.6 10 1 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 PVD27081.1 - 3.2e-17 62.1 13.8 0.027 14.9 0.3 8.7 9 0 0 9 9 9 5 Ankyrin repeat PPR PF01535.20 PVD27081.1 - 0.2 12.0 0.2 11 6.5 0.1 3.4 3 0 0 3 3 3 0 PPR repeat zf-GRF PF06839.12 PVD27084.1 - 7.9 6.7 8.8 12 6.1 0.2 3.7 3 0 0 3 3 3 0 GRF zinc finger zf-C2H2_6 PF13912.6 PVD27085.1 - 4.9e-07 29.6 25.1 0.00036 20.5 1.6 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger CpXC PF14353.6 PVD27085.1 - 2e-06 27.9 12.2 0.011 15.8 0.2 3.9 3 1 0 3 3 3 3 CpXC protein zf-C2H2 PF00096.26 PVD27085.1 - 4.2e-06 26.9 10.4 0.18 12.3 0.1 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27085.1 - 2.6e-05 24.7 22.8 0.054 14.3 0.2 6.1 7 0 0 7 7 5 3 C2H2-type zinc finger DNA_RNApol_7kD PF03604.13 PVD27085.1 - 0.00029 20.5 3.7 8.3 6.2 0.1 4.4 4 0 0 4 4 4 3 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 PVD27085.1 - 0.0071 15.9 0.3 15 5.2 0.0 3.6 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 PVD27085.1 - 0.011 15.4 9.9 4.9 7.0 0.2 4.5 6 0 0 6 6 6 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 PVD27085.1 - 0.05 13.7 8.5 13 6.0 0.0 4.2 4 0 0 4 4 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 PVD27085.1 - 0.13 12.7 4.3 38 4.9 0.1 4.2 4 0 0 4 4 4 0 Recombinase zinc beta ribbon domain FANCI_S1-cap PF14674.6 PVD27085.1 - 0.17 12.0 0.6 27 4.9 0.1 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap zf-C2H2_8 PF15909.5 PVD27085.1 - 3 8.2 13.4 7.3 7.0 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc ribbon Gal-3-0_sulfotr PF06990.11 PVD27086.1 - 5.3e-48 163.9 2.7 6.4e-48 163.6 2.7 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD27086.1 - 4.6e-05 23.4 0.1 0.00016 21.7 0.1 2.0 1 1 1 2 2 2 1 Sulfotransferase family zf-C2H2 PF00096.26 PVD27087.1 - 2.9e-63 206.9 121.6 1.7e-05 25.0 3.4 16.4 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27087.1 - 2.1e-50 165.0 118.4 0.00054 20.6 2.6 16.4 16 0 0 16 16 16 14 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD27087.1 - 1.2e-49 164.6 111.9 1.2e-09 38.1 0.7 16.1 16 0 0 16 16 16 12 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD27087.1 - 9.7e-20 70.1 113.8 0.0011 18.9 0.4 15.2 15 0 0 15 15 15 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD27087.1 - 3.1e-13 49.6 96.4 0.015 15.6 1.5 15.1 14 1 1 15 15 15 10 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 PVD27087.1 - 1.5e-07 31.4 63.9 0.0066 16.5 1.9 9.8 7 1 3 10 10 10 6 Zinc ribbon domain zf-met PF12874.7 PVD27087.1 - 0.00036 20.8 94.9 0.19 12.1 1.6 14.7 15 0 0 15 15 15 8 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD27087.1 - 0.0039 16.9 78.1 0.012 15.3 2.2 13.4 14 0 0 14 14 13 5 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 PVD27087.1 - 0.0073 17.0 59.0 0.16 12.6 3.3 9.1 3 3 3 7 7 7 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 PVD27087.1 - 0.017 14.9 1.4 0.017 14.9 1.4 15.1 14 4 0 14 14 13 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 PVD27087.1 - 0.039 14.3 62.3 0.11 12.8 8.1 7.5 3 2 5 8 8 8 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 PVD27087.1 - 0.16 12.8 71.0 0.59 10.9 2.2 8.1 2 2 8 10 10 10 0 zinc-ribbon family zf-C2H2 PF00096.26 PVD27088.1 - 2.4e-28 97.0 102.3 1.1e-05 25.6 0.6 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27088.1 - 2.8e-20 71.2 100.9 0.0034 18.1 0.5 12.7 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD27088.1 - 6e-07 29.6 73.0 0.051 13.9 3.0 12.0 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD27088.1 - 3e-05 24.3 89.9 0.005 17.2 1.3 12.8 13 1 0 13 13 13 6 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 PVD27088.1 - 0.048 13.3 0.1 0.048 13.3 0.1 9.3 7 2 3 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 PVD27088.1 - 0.11 13.2 39.8 6.8 7.4 0.4 8.5 4 1 5 9 9 9 0 Zinc finger C2H2-type, 3 repeats HNH_2 PF13391.6 PVD27088.1 - 0.48 10.6 3.1 2.4 8.3 1.7 2.8 2 0 0 2 2 2 0 HNH endonuclease GpcrRhopsn4 PF10192.9 PVD27089.1 - 7.1e-63 212.4 21.9 9.4e-63 212.0 21.9 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain CN_hydrolase PF00795.22 PVD27089.1 - 9.5e-62 208.7 0.0 1.5e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FA_hydroxylase PF04116.13 PVD27090.1 - 1.3e-07 32.0 2.5 1.4e-07 31.9 2.5 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Pkinase_Tyr PF07714.17 PVD27091.1 - 1.5e-69 234.2 0.0 2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD27091.1 - 4.2e-33 114.8 0.0 8.2e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 PVD27091.1 - 1.8e-20 73.3 0.9 2.6e-10 40.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27091.1 - 2.2e-15 56.7 2.4 4.5e-07 30.1 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD27091.1 - 8.3e-15 54.9 1.0 6.8e-08 32.7 0.0 4.1 3 1 1 4 4 4 3 Immunoglobulin V-set domain I-set PF07679.16 PVD27091.1 - 3.3e-12 46.3 0.0 0.00012 22.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD27091.1 - 2.2e-09 37.4 0.0 0.089 13.0 0.0 3.8 3 2 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 PVD27091.1 - 3.3e-05 23.8 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain DUF4244 PF14029.6 PVD27091.1 - 0.084 12.3 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Ig_6 PF18452.1 PVD27091.1 - 0.1 12.2 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain DUF4381 PF14316.6 PVD27091.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 PVD27091.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Peptidase_S8 PF00082.22 PVD27092.1 - 7.7e-40 137.0 2.3 7.7e-40 137.0 2.3 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 PVD27092.1 - 3.2e-19 68.8 0.0 8.6e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 PVD27092.1 - 1.9e-06 28.6 6.1 9.6e-06 26.3 2.3 2.8 2 1 0 2 2 2 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 PVD27092.1 - 0.036 14.6 0.1 0.036 14.6 0.1 1.7 2 0 0 2 2 2 0 N-terminal of Subtilase family DnaJ PF00226.31 PVD27093.1 - 2e-20 72.7 0.1 5.2e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain ig PF00047.25 PVD27096.1 - 1.6e-06 28.2 8.3 0.047 13.9 0.9 4.9 4 1 0 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.6 PVD27096.1 - 1.1e-05 25.9 10.9 0.049 14.2 0.5 4.9 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27096.1 - 2.4e-05 24.6 10.2 0.12 12.7 0.3 4.5 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD27096.1 - 0.0011 19.0 0.9 1.1 9.4 0.1 4.1 4 1 0 4 4 4 1 Immunoglobulin I-set domain RVT_1 PF00078.27 PVD27098.1 - 4.4e-07 29.6 0.0 5.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4347 PF14252.6 PVD27099.1 - 0.0066 16.3 0.1 15 5.4 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4347) NODP PF07684.12 PVD27099.1 - 0.0098 16.0 8.3 6.4 7.0 0.1 3.7 4 0 0 4 4 4 3 NOTCH protein FlgM PF04316.13 PVD27099.1 - 0.014 15.8 0.0 22 5.5 0.0 3.2 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM Me-amine-dh_L PF02975.14 PVD27099.1 - 0.42 11.1 8.4 1.2 9.6 0.5 3.3 2 1 1 3 3 3 0 Methylamine dehydrogenase, L chain Pox_TAA1 PF03295.14 PVD27100.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal Sec2p PF06428.11 PVD27102.1 - 0.0045 16.9 1.2 3.4 7.7 0.1 2.9 3 0 0 3 3 3 2 GDP/GTP exchange factor Sec2p TcdB_toxin_midN PF12256.8 PVD27102.1 - 0.067 12.5 0.0 42 3.4 0.0 3.4 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region TMEM154 PF15102.6 PVD27103.1 - 5.9e-05 23.0 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Alpha_GJ PF03229.13 PVD27103.1 - 0.00012 22.6 1.0 0.00012 22.6 1.0 1.8 2 0 0 2 2 2 1 Alphavirus glycoprotein J Shisa PF13908.6 PVD27103.1 - 0.00079 19.7 0.7 0.0031 17.8 0.7 1.8 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 PVD27103.1 - 0.00079 20.1 0.3 0.0021 18.7 0.0 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red BatD PF13584.6 PVD27103.1 - 0.0018 17.2 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance AJAP1_PANP_C PF15298.6 PVD27103.1 - 0.0074 16.5 1.1 0.012 15.9 1.1 1.4 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF3439 PF11921.8 PVD27103.1 - 0.023 14.6 2.1 0.056 13.4 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HemY_N PF07219.13 PVD27103.1 - 0.089 13.0 0.3 0.089 13.0 0.3 1.6 2 0 0 2 2 1 0 HemY protein N-terminus Cadherin_C_2 PF16492.5 PVD27103.1 - 0.16 12.8 3.1 0.53 11.1 0.1 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4381 PF14316.6 PVD27103.1 - 0.42 10.8 0.1 0.42 10.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.11 PVD27103.1 - 0.49 10.0 0.0 0.49 10.0 0.0 1.7 2 0 0 2 2 1 0 Baculovirus 11 kDa family Ig_3 PF13927.6 PVD27104.1 - 0.38 11.4 5.0 2.8 8.6 0.4 3.6 4 0 0 4 4 4 0 Immunoglobulin domain C2-set_2 PF08205.12 PVD27105.1 - 0.061 13.4 1.2 4.5 7.4 0.0 4.0 5 0 0 5 5 5 0 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27106.1 - 0.049 13.8 1.3 6.1 7.1 0.2 3.3 3 1 0 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.12 PVD27106.1 - 0.096 12.8 1.5 1.5 8.9 1.0 3.2 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain CytochromB561_N PF09786.9 PVD27109.1 - 0.0015 17.6 0.1 0.0022 17.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Sensor PF13796.6 PVD27109.1 - 0.026 14.6 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative sensor Myc_target_1 PF15179.6 PVD27109.1 - 0.027 14.4 2.3 0.21 11.5 0.1 2.2 1 1 1 2 2 2 0 Myc target protein 1 ig PF00047.25 PVD27110.1 - 0.0018 18.4 3.3 1.3 9.2 0.1 2.9 2 0 0 2 2 2 2 Immunoglobulin domain DUF485 PF04341.12 PVD27110.1 - 0.025 14.5 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Stevor PF17410.2 PVD27110.1 - 0.046 13.3 0.1 0.088 12.3 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PVD27110.1 - 0.089 13.7 0.4 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.6 PVD27111.1 - 0.0099 15.4 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) FixQ PF05545.11 PVD27111.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF485 PF04341.12 PVD27111.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Stevor PF17410.2 PVD27111.1 - 0.18 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Adeno_E3_CR2 PF02439.15 PVD27111.1 - 0.24 11.2 1.6 0.46 10.3 1.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.6 PVD27112.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF485 PF04341.12 PVD27112.1 - 0.034 14.1 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SKG6 PF08693.10 PVD27112.1 - 0.069 12.6 6.4 0.27 10.7 1.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Stevor PF17410.2 PVD27112.1 - 0.088 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3149 PF11346.8 PVD27112.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Ig_2 PF13895.6 PVD27113.1 - 0.0021 18.4 0.1 0.0033 17.7 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain SKG6 PF08693.10 PVD27113.1 - 0.5 9.8 5.0 4.4 6.8 0.7 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain zf-C2H2_jaz PF12171.8 PVD27114.1 - 0.04 14.2 2.2 5.2 7.5 0.9 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding Ets PF00178.22 PVD27115.1 - 1.8e-36 124.4 1.1 3.3e-36 123.6 1.1 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 PVD27115.1 - 4.5e-28 97.1 0.6 7.6e-28 96.3 0.6 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 PVD27115.1 - 0.14 12.0 0.2 1.4 8.8 0.1 2.4 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) C2 PF00168.30 PVD27116.1 - 1.4e-09 38.1 1.2 2.2e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 C2 domain TFIIA PF03153.13 PVD27116.1 - 4.1 7.3 19.6 4.7 7.1 16.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 PVD27117.1 - 1.5e-22 79.5 17.5 0.00035 21.3 0.4 9.3 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD27117.1 - 3.1e-11 43.4 2.9 0.14 12.5 0.1 6.8 6 3 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 PVD27118.1 - 0.00057 19.8 0.1 2.1 8.5 0.0 3.6 3 0 0 3 3 3 2 NHL repeat Apolipoprotein PF01442.18 PVD27118.1 - 1.4 8.7 12.0 0.22 11.3 7.7 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain zf-B_box PF00643.24 PVD27118.1 - 9.3 6.5 7.2 19 5.5 7.2 1.5 1 0 0 1 1 1 0 B-box zinc finger DHHC PF01529.20 PVD27119.1 - 1.1e-33 116.1 7.5 1.1e-33 116.1 7.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3925 PF13063.6 PVD27119.1 - 0.22 11.7 2.3 0.43 10.8 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) APP_E2 PF12925.7 PVD27120.1 - 1.2e-39 136.0 18.1 1.2e-39 136.0 18.1 3.1 2 1 0 2 2 2 1 E2 domain of amyloid precursor protein APP_N PF02177.16 PVD27120.1 - 1.3e-25 89.7 0.4 4.7e-24 84.7 0.0 3.0 2 1 1 3 3 3 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.9 PVD27120.1 - 2.4e-25 88.8 0.5 2.4e-25 88.8 0.5 2.5 2 0 0 2 2 2 1 Beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.7 PVD27120.1 - 8e-20 71.3 9.0 8e-20 71.3 9.0 2.3 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD Amnionless PF14828.6 PVD27120.1 - 2.1e-05 23.6 0.9 3.3e-05 22.9 0.9 1.3 1 0 0 1 1 1 1 Amnionless Zip PF02535.22 PVD27120.1 - 0.0096 15.2 1.3 0.019 14.2 1.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Cytokin_check_N PF10407.9 PVD27120.1 - 0.026 14.5 0.7 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Remorin_C PF03763.13 PVD27120.1 - 1.8 8.5 10.2 0.086 12.7 3.2 2.4 2 1 0 2 2 2 0 Remorin, C-terminal region MFS_1 PF07690.16 PVD27121.1 - 2.3e-49 168.2 49.1 6.3e-49 166.8 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_5 PF16085.5 PVD27121.1 - 0.23 11.6 4.5 0.78 9.9 4.5 1.9 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III Chlorovi_GP_rpt PF06598.11 PVD27121.1 - 5.7 7.1 7.0 9.2 6.4 2.6 2.6 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat RVT_1 PF00078.27 PVD27122.1 - 1.8e-15 57.1 0.1 2.6e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Synaptobrevin PF00957.21 PVD27122.1 - 0.059 13.2 0.3 0.26 11.1 0.1 2.1 1 1 1 2 2 2 0 Synaptobrevin V-set PF07686.17 PVD27123.1 - 6.7e-17 61.6 9.9 8.1e-06 26.0 0.1 4.8 4 0 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 PVD27123.1 - 9.1e-13 48.2 15.1 0.012 15.7 0.3 5.2 4 2 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.6 PVD27123.1 - 6.4e-12 45.9 16.4 0.014 15.9 1.0 5.2 4 1 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 PVD27123.1 - 7.3e-09 35.9 23.5 0.0016 18.7 0.8 5.9 5 1 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27123.1 - 1.4e-07 31.5 5.6 0.088 12.9 0.1 4.3 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain I-set PF07679.16 PVD27123.1 - 4.1e-07 30.0 8.2 0.029 14.4 0.1 4.7 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_6 PF18452.1 PVD27123.1 - 2.7e-05 23.6 0.3 0.21 11.2 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 PVD27123.1 - 0.00085 19.7 8.2 4.6 7.7 0.1 4.0 4 0 0 4 4 4 3 Immunoglobulin C1-set domain Egh16-like PF11327.8 PVD27123.1 - 0.0015 19.0 2.6 1.1 9.6 0.1 2.7 2 0 0 2 2 2 2 Egh16-like virulence factor BslA PF17735.1 PVD27123.1 - 0.0021 18.1 1.7 1.5 8.8 0.1 2.7 2 0 0 2 2 2 2 Biofilm surface layer A Ig_4 PF16680.5 PVD27123.1 - 0.015 15.6 9.4 11 6.3 0.1 4.7 5 0 0 5 5 4 0 T-cell surface glycoprotein CD3 delta chain DUF4307 PF14155.6 PVD27123.1 - 0.065 13.1 3.8 4.9 7.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) WWE PF02825.20 PVD27123.1 - 0.14 12.8 0.2 0.37 11.4 0.2 1.8 1 0 0 1 1 1 0 WWE domain Tudor_2 PF18104.1 PVD27123.1 - 0.62 9.8 2.8 1.1 9.0 0.1 2.7 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain V-set PF07686.17 PVD27124.1 - 1.9e-06 28.0 0.0 0.075 13.2 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 PVD27124.1 - 2.1e-05 24.5 0.0 0.33 11.0 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain Izumo-Ig PF16706.5 PVD27124.1 - 0.0017 18.4 0.0 0.63 10.1 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain ig PF00047.25 PVD27124.1 - 0.0064 16.6 0.2 0.59 10.3 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27124.1 - 0.0074 16.6 2.4 0.47 10.8 0.0 3.1 4 0 0 4 4 4 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27124.1 - 0.013 16.0 0.2 9.9 6.8 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 PVD27124.1 - 0.11 12.0 0.3 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain CUB PF00431.20 PVD27125.1 - 5.5e-40 136.1 7.9 7.4e-12 45.6 0.0 6.3 3 1 3 6 6 6 6 CUB domain DUF3558 PF12079.8 PVD27125.1 - 2.1e-05 24.6 0.9 0.55 10.2 0.1 4.0 2 1 0 3 3 3 2 Protein of unknown function (DUF3558) CUB_2 PF02408.20 PVD27125.1 - 0.01 15.6 16.3 1.3 8.8 0.0 5.2 2 1 3 5 5 5 0 CUB-like domain Myotoxins PF00819.17 PVD27125.1 - 1.5 9.1 3.3 49 4.3 0.0 3.4 4 0 0 4 4 4 0 Myotoxin, crotamine IL12p40_C PF10420.9 PVD27125.1 - 2.6 8.6 4.4 81 3.8 0.1 3.7 5 0 0 5 5 5 0 Cytokine interleukin-12p40 C-terminus CUB PF00431.20 PVD27126.1 - 5.4e-45 152.2 10.5 2.8e-11 43.7 0.0 5.9 2 1 4 6 6 6 5 CUB domain Phage_30_8 PF06019.11 PVD27126.1 - 5.1e-05 23.2 0.5 0.012 15.5 0.0 4.0 4 0 0 4 4 4 1 Phage GP30.8 protein CUB_2 PF02408.20 PVD27126.1 - 0.0068 16.2 24.0 1.2 9.0 1.0 5.9 3 3 2 6 6 6 4 CUB-like domain CUB PF00431.20 PVD27127.1 - 1.8e-52 176.3 11.2 4.3e-09 36.7 0.0 8.2 8 1 0 8 8 8 6 CUB domain CUB_2 PF02408.20 PVD27127.1 - 3.2e-14 52.7 11.7 0.03 14.1 0.1 5.8 5 0 0 5 5 5 5 CUB-like domain Macoilin PF09726.9 PVD27127.1 - 1.4 7.4 10.7 1.9 7.0 10.7 1.1 1 0 0 1 1 1 0 Macoilin family CUB PF00431.20 PVD27128.1 - 1.7e-44 150.6 9.2 3.1e-08 33.9 0.0 7.7 4 3 4 8 8 8 5 CUB domain V-set PF07686.17 PVD27128.1 - 4.7e-07 30.0 1.4 0.00015 21.9 0.1 3.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD27128.1 - 3.8e-06 27.4 16.5 0.35 11.5 1.0 6.8 7 0 0 7 7 7 2 Immunoglobulin domain CUB_2 PF02408.20 PVD27128.1 - 4.7e-06 26.4 15.2 0.34 10.7 0.1 6.5 4 1 2 6 6 6 3 CUB-like domain I-set PF07679.16 PVD27128.1 - 6.3e-05 23.0 1.2 0.16 12.0 0.1 4.1 4 0 0 4 4 4 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 PVD27128.1 - 8.2e-05 22.6 2.3 0.54 10.4 0.1 4.0 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain ig PF00047.25 PVD27128.1 - 0.00018 21.6 7.1 1.4 9.2 0.1 5.1 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27128.1 - 0.0095 16.3 15.3 1.3 9.4 0.4 6.9 7 1 0 7 7 7 2 Immunoglobulin domain Ig_6 PF18452.1 PVD27128.1 - 0.022 14.3 0.2 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Neocarzinostat PF00960.18 PVD27128.1 - 0.051 13.6 5.2 0.13 12.3 1.1 3.5 3 0 0 3 3 3 0 Neocarzinostatin family WWE PF02825.20 PVD27128.1 - 0.33 11.6 6.3 5.9 7.6 0.3 2.7 2 0 0 2 2 2 0 WWE domain bMG6 PF17962.1 PVD27128.1 - 0.41 10.8 3.5 0.66 10.1 0.2 2.6 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 C1-set PF07654.15 PVD27128.1 - 0.75 10.2 5.4 16 5.9 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin C1-set domain Plasmid_stab_B PF10784.9 PVD27129.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Plasmid stability protein IMUP PF15761.5 PVD27129.1 - 0.16 12.7 1.5 0.22 12.2 1.5 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein V-set PF07686.17 PVD27130.1 - 1.4e-06 28.4 0.3 4.1e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD27130.1 - 4.5e-05 23.7 4.1 1.6 9.2 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD27130.1 - 0.00029 21.0 0.4 0.072 13.3 0.0 2.7 1 1 1 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD27130.1 - 0.0011 18.9 0.4 0.5 10.5 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27130.1 - 0.0012 19.4 5.6 0.0059 17.2 0.9 2.9 2 2 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 PVD27130.1 - 0.21 12.0 2.5 7.5 7.0 0.0 3.5 4 0 0 4 4 4 0 Immunoglobulin C1-set domain Ig_2 PF13895.6 PVD27131.1 - 2.6e-07 30.9 2.1 0.19 12.1 0.2 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 PVD27131.1 - 1.1e-05 25.9 5.3 0.0057 17.2 0.5 3.2 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD27131.1 - 3.2e-05 24.1 1.0 0.00012 22.2 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 PVD27131.1 - 0.00081 19.4 0.3 0.43 10.7 0.1 2.9 3 1 0 3 3 3 2 Immunoglobulin I-set domain WWE PF02825.20 PVD27131.1 - 0.028 15.0 0.3 0.054 14.1 0.3 1.5 1 0 0 1 1 1 0 WWE domain C1-set PF07654.15 PVD27131.1 - 0.95 9.9 4.8 5.9 7.3 0.2 3.8 4 1 0 4 4 4 0 Immunoglobulin C1-set domain V-set PF07686.17 PVD27132.1 - 1.3e-06 28.5 0.6 3.8e-06 27.0 0.4 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD27132.1 - 0.0018 18.3 0.1 0.004 17.2 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD27132.1 - 0.0078 16.4 0.2 0.015 15.4 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27132.1 - 0.0095 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD27132.1 - 0.014 15.9 1.4 0.025 15.2 0.6 2.0 2 1 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 PVD27132.1 - 0.043 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF2207 PF09972.9 PVD27133.1 - 0.00056 18.8 0.0 0.00062 18.7 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Amnionless PF14828.6 PVD27133.1 - 0.001 18.0 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Amnionless Adeno_E3_CR2 PF02439.15 PVD27133.1 - 0.0014 18.4 1.1 0.0023 17.6 1.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 PVD27133.1 - 0.0048 16.8 0.3 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Syndecan domain EphA2_TM PF14575.6 PVD27133.1 - 0.0091 16.9 0.0 0.022 15.6 0.0 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD27133.1 - 0.01 16.1 0.1 0.045 14.0 0.0 2.0 2 1 0 2 2 2 0 Orf78 (ac78) SKG6 PF08693.10 PVD27133.1 - 0.092 12.2 7.3 0.15 11.5 7.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2970 PF11174.8 PVD27133.1 - 0.11 12.4 1.8 0.2 11.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) OAD_gamma PF04277.13 PVD27133.1 - 0.13 12.8 0.0 0.29 11.8 0.0 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Stevor PF17410.2 PVD27133.1 - 0.14 11.7 0.5 0.27 10.7 0.3 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4307 PF14155.6 PVD27133.1 - 0.24 11.2 2.7 8.6 6.2 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) V-set PF07686.17 PVD27133.1 - 0.53 10.5 5.3 0.24 11.6 2.6 1.8 2 0 0 2 2 1 0 Immunoglobulin V-set domain Branch PF02485.21 PVD27134.1 - 1.5e-25 90.2 0.0 2.6e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27135.1 - 5.3e-37 127.7 0.0 7.1e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27136.1 - 1.9e-36 125.9 0.0 2.7e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27137.1 - 1.4e-36 126.2 0.0 2.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27138.1 - 1.9e-34 119.3 0.1 4.1e-34 118.2 0.1 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27139.1 - 7e-36 124.0 0.0 1e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 PVD27140.1 - 7.5e-35 120.6 0.0 1.5e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Adeno_E3_CR2 PF02439.15 PVD27141.1 - 0.0011 18.7 1.3 0.0017 18.0 1.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 PVD27141.1 - 0.002 18.0 0.4 0.0026 17.7 0.4 1.2 1 0 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 PVD27141.1 - 0.0033 17.2 0.3 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator Amnionless PF14828.6 PVD27141.1 - 0.0038 16.1 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 PVD27141.1 - 0.015 16.1 0.0 0.03 15.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 PVD27141.1 - 0.019 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 PVD27141.1 - 0.03 14.2 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Rifin Sucrose_synth PF00862.19 PVD27141.1 - 0.03 12.6 0.1 0.039 12.3 0.1 1.1 1 0 0 1 1 1 0 Sucrose synthase DUF4448 PF14610.6 PVD27141.1 - 0.032 14.0 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 PVD27141.1 - 0.039 14.2 0.1 0.056 13.8 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Stevor PF17410.2 PVD27141.1 - 0.054 13.0 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Protocadherin PF08374.11 PVD27141.1 - 0.073 13.0 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin ASFV_J13L PF05568.11 PVD27141.1 - 0.084 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4381 PF14316.6 PVD27141.1 - 0.084 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zinc_ribbon_11 PF11682.8 PVD27141.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon BatD PF13584.6 PVD27141.1 - 0.13 11.0 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance SARAF PF06682.12 PVD27141.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Phage_Gp23 PF10669.9 PVD27141.1 - 0.43 10.9 3.5 0.36 11.2 1.3 1.7 1 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) VirB3 PF05101.13 PVD27142.1 - 0.14 12.4 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein FTH PF01827.27 PVD27143.1 - 5.8e-05 22.9 0.0 6 6.7 0.0 3.2 3 0 0 3 3 3 3 FTH domain EF-hand_7 PF13499.6 PVD27143.1 - 8.8e-05 22.9 0.0 4.6 7.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair Xrn1_D3 PF18194.1 PVD27143.1 - 0.017 15.2 1.2 40 4.4 0.0 3.2 3 0 0 3 3 3 0 Exoribonuclease 1 Domain-3 APS-reductase_C PF12139.8 PVD27143.1 - 0.071 13.3 0.0 1.2e+02 3.0 0.0 3.2 3 0 0 3 3 3 0 Adenosine-5'-phosphosulfate reductase beta subunit I-set PF07679.16 PVD27144.1 - 3e-09 36.8 0.6 0.00032 20.7 0.3 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27144.1 - 2.8e-08 34.2 4.6 1.9e-06 28.4 0.7 3.4 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27144.1 - 6.2e-06 26.5 0.8 6.2e-06 26.5 0.8 3.0 3 1 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD27144.1 - 0.0013 18.9 1.8 0.15 12.2 1.1 3.3 2 1 0 2 2 2 1 Immunoglobulin domain SUa-2TM PF18179.1 PVD27144.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF2975 PF11188.8 PVD27144.1 - 0.051 13.5 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4834 PF16118.5 PVD27144.1 - 0.056 14.4 0.6 0.19 12.7 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ECSCR PF15820.5 PVD27144.1 - 0.09 12.6 0.4 0.2 11.5 0.4 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Cadherin_C_2 PF16492.5 PVD27144.1 - 0.11 13.3 0.1 0.46 11.3 0.1 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Baculo_11_kDa PF06143.11 PVD27144.1 - 0.16 11.6 0.8 0.47 10.0 0.8 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.6 PVD27144.1 - 0.69 9.8 0.0 0.69 9.8 0.0 2.6 2 1 0 2 2 2 0 TMEM154 protein family I-set PF07679.16 PVD27145.1 - 4.7e-06 26.6 2.1 0.13 12.3 0.3 4.1 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27145.1 - 6.7e-05 23.4 16.7 0.003 18.1 1.9 4.1 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27145.1 - 0.00043 20.5 0.8 0.00043 20.5 0.8 3.9 3 2 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27146.1 - 3.1e-09 37.3 8.6 7.5e-08 32.9 0.3 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27146.1 - 2.3e-08 34.3 5.1 7.9e-07 29.3 0.2 3.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD27146.1 - 2.3e-07 30.8 0.1 0.00079 19.4 0.1 3.2 3 1 0 3 3 3 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD27146.1 - 0.00039 20.4 1.3 0.22 11.6 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27146.1 - 0.031 14.5 4.2 0.058 13.6 0.3 3.3 3 1 0 3 3 3 0 Immunoglobulin domain Ig_3 PF13927.6 PVD27147.1 - 2.3e-10 40.9 6.4 2.1e-05 25.0 0.2 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD27147.1 - 1.2e-07 31.7 0.1 0.0011 19.0 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27147.1 - 1.6e-05 25.2 4.0 0.0011 19.3 0.1 2.8 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD27147.1 - 0.00018 21.5 0.7 0.97 9.5 0.5 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27147.1 - 0.041 14.1 2.3 9.1 6.5 0.2 3.9 4 0 0 4 4 4 0 Immunoglobulin V-set domain I-set PF07679.16 PVD27148.1 - 1.6e-09 37.7 2.4 0.00079 19.4 0.1 4.6 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27148.1 - 1.3e-08 35.4 12.8 1.7e-06 28.5 1.4 4.4 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27148.1 - 4.6e-06 26.9 7.1 5.9e-06 26.5 0.7 3.2 4 0 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27148.1 - 3.1e-05 23.9 5.1 0.046 13.8 0.4 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27148.1 - 0.0011 19.1 11.1 0.58 10.4 0.7 4.3 4 1 0 4 4 4 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27148.1 - 0.036 14.1 0.9 0.19 11.8 0.1 2.6 3 0 0 3 3 3 0 C17orf99 Ig domain I-set PF07679.16 PVD27149.1 - 4.9e-09 36.1 6.5 0.00043 20.3 0.2 4.7 4 2 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27149.1 - 2.5e-08 34.4 16.7 6.3e-07 29.9 0.6 5.4 5 1 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27149.1 - 2.1e-07 31.1 8.9 5.4e-07 29.8 0.5 4.0 4 0 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27149.1 - 0.0001 22.3 2.8 0.18 11.9 0.2 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27149.1 - 0.00033 20.8 11.4 0.13 12.5 0.7 4.8 5 1 0 5 5 5 2 Immunoglobulin domain Ig_3 PF13927.6 PVD27150.1 - 2.3e-10 40.9 7.1 9.1e-07 29.4 0.3 3.8 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27150.1 - 4.7e-06 26.8 11.8 8.7e-06 26.0 0.4 4.2 3 1 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 PVD27150.1 - 2.9e-05 24.0 0.4 0.0018 18.3 0.0 3.4 3 1 0 3 3 3 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD27150.1 - 0.00028 20.9 0.4 0.39 10.8 0.0 3.1 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27150.1 - 0.018 15.2 4.9 1.3 9.3 0.7 4.2 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 PVD27151.1 - 2.3e-07 30.8 0.8 0.023 14.8 0.2 3.2 2 1 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD27151.1 - 8.7e-07 28.9 3.3 0.0023 18.0 0.7 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27151.1 - 2.1e-06 28.2 10.3 0.00086 19.9 2.2 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27151.1 - 0.00028 21.1 1.4 0.00028 21.1 1.4 3.1 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD27151.1 - 0.059 13.6 11.1 0.4 10.9 0.9 4.1 3 1 0 3 3 3 0 Immunoglobulin domain TMEM132D_C PF15706.5 PVD27151.1 - 0.19 11.5 0.8 0.48 10.2 0.4 1.8 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term V-set PF07686.17 PVD27151.1 - 1 9.6 7.2 5.3 7.2 0.4 3.7 2 1 1 3 3 3 0 Immunoglobulin V-set domain Protocadherin PF08374.11 PVD27151.1 - 4.4 7.2 7.7 0.62 10.0 1.4 2.3 2 1 0 2 2 2 0 Protocadherin Self-incomp_S1 PF05938.11 PVD27151.1 - 6.6 7.3 8.2 4.9 7.8 0.4 3.1 2 1 0 3 3 3 0 Plant self-incompatibility protein S1 I-set PF07679.16 PVD27153.1 - 4.1e-08 33.2 2.9 0.00031 20.8 0.3 4.6 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27153.1 - 7.6e-07 29.6 1.8 7.6e-07 29.6 1.8 4.7 4 1 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27153.1 - 1.2e-06 28.8 0.9 1.2e-06 28.8 0.9 4.7 4 2 1 5 5 5 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27153.1 - 8.5e-05 22.5 1.5 0.31 11.1 0.1 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27153.1 - 0.0011 19.1 9.0 0.073 13.2 1.1 4.9 3 1 0 3 3 3 1 Immunoglobulin domain Myelin-PO_C PF10570.9 PVD27153.1 - 0.13 12.7 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region V-set PF07686.17 PVD27153.1 - 6.9 6.9 9.2 18 5.6 0.3 4.8 3 1 0 3 3 3 0 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD27154.1 - 3.7e-06 27.4 10.6 1.6e-05 25.4 0.9 4.4 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27154.1 - 0.00017 21.8 1.0 0.00017 21.8 1.0 5.2 5 1 1 6 6 6 2 Immunoglobulin domain I-set PF07679.16 PVD27154.1 - 0.0002 21.4 4.3 0.1 12.7 1.0 3.7 3 1 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 PVD27154.1 - 0.00089 19.4 7.6 0.12 12.5 1.3 4.5 3 2 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD27154.1 - 0.012 15.7 4.6 0.041 13.9 1.1 3.4 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD27154.1 - 8 6.9 9.1 8.6 6.8 0.3 4.6 5 0 0 5 5 5 0 Immunoglobulin C1-set domain Ldl_recept_a PF00057.18 PVD27155.1 - 2.7e-19 69.1 62.7 1.1e-05 25.5 13.5 6.7 6 1 1 7 7 7 5 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD27155.1 - 0.0095 16.7 0.0 0.0095 16.7 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain I-set PF07679.16 PVD27156.1 - 1.6e-07 31.3 0.4 0.0054 16.8 0.1 4.1 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27156.1 - 2.1e-06 28.2 6.0 2.3e-05 24.9 0.5 4.2 4 0 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27156.1 - 0.00026 21.3 0.8 0.00026 21.3 0.8 4.4 5 0 0 5 5 5 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27156.1 - 0.0014 18.6 0.8 0.41 10.8 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27156.1 - 0.037 14.2 1.6 1.2 9.4 0.4 3.7 3 1 0 3 3 3 0 Immunoglobulin domain WGR PF05406.15 PVD27156.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 WGR domain TMEM100 PF16311.5 PVD27158.1 - 0.036 13.7 0.4 0.085 12.5 0.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 I-set PF07679.16 PVD27159.1 - 4.2e-07 29.9 0.6 0.03 14.4 0.1 4.4 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27159.1 - 1.5e-05 25.2 0.6 0.00012 22.3 0.6 2.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27159.1 - 5.5e-05 23.7 8.5 0.00067 20.2 0.5 4.1 4 2 0 4 4 4 2 Immunoglobulin domain RIFIN PF02009.16 PVD27160.1 - 3.8e-07 30.3 7.2 0.0058 16.6 1.8 2.3 2 0 0 2 2 2 2 Rifin Orf78 PF06024.12 PVD27160.1 - 0.00021 21.6 1.5 0.065 13.5 0.1 2.4 2 0 0 2 2 2 1 Orf78 (ac78) Insulin_TMD PF17870.1 PVD27160.1 - 0.00021 21.3 1.3 0.00021 21.3 1.3 2.6 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment Protocadherin PF08374.11 PVD27160.1 - 0.00051 20.1 6.9 0.029 14.4 1.2 2.4 2 0 0 2 2 2 2 Protocadherin DUF4064 PF13273.6 PVD27160.1 - 0.0023 18.2 0.7 1.4 9.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) Stevor PF17410.2 PVD27160.1 - 0.0031 17.1 4.6 0.13 11.8 0.1 3.0 3 0 0 3 3 3 1 Subtelomeric Variable Open Reading frame DUF3377 PF11857.8 PVD27160.1 - 0.0058 16.5 2.8 1.3 9.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3377) DAG1 PF05454.11 PVD27160.1 - 0.0059 16.0 5.0 0.14 11.6 0.4 2.2 2 0 0 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2207 PF09972.9 PVD27160.1 - 0.0072 15.1 0.0 0.69 8.6 0.0 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 PVD27160.1 - 0.0077 16.1 11.9 0.029 14.3 1.1 2.6 2 1 0 2 2 2 1 TMEM154 protein family Syndecan PF01034.20 PVD27160.1 - 0.028 14.3 10.3 0.8 9.7 2.5 2.5 2 0 0 2 2 2 0 Syndecan domain DUF4448 PF14610.6 PVD27160.1 - 0.04 13.7 0.3 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 PVD27160.1 - 0.058 14.3 14.8 0.06 14.2 1.8 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 PVD27160.1 - 0.11 12.1 13.3 0.12 11.9 3.5 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Adeno_E3_CR2 PF02439.15 PVD27160.1 - 0.14 11.9 14.1 0.074 12.8 4.4 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 PVD27160.1 - 0.22 11.8 3.0 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein melan-A Zf_RING PF16744.5 PVD27160.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.5 3 0 0 3 3 2 0 KIAA1045 RING finger ADAM_CR_2 PF17771.1 PVD27160.1 - 0.26 11.8 6.6 3.2 8.3 0.4 3.4 3 0 0 3 3 2 0 ADAM cysteine-rich domain DUF3810 PF12725.7 PVD27160.1 - 0.91 8.8 5.0 1.1 8.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) G3P_acyltransf PF02660.15 PVD27160.1 - 0.95 9.5 6.4 23 5.0 0.3 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase FeoB_associated PF12669.7 PVD27160.1 - 1.2 9.6 13.9 0.22 11.9 2.1 3.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein EGF_3 PF12947.7 PVD27160.1 - 3 8.1 10.9 4.7 7.5 1.2 3.5 3 0 0 3 3 2 0 EGF domain ECSCR PF15820.5 PVD27160.1 - 3.5 7.5 12.9 2.7 7.9 1.0 3.0 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator SKG6 PF08693.10 PVD27160.1 - 4.3 6.8 17.2 0.26 10.7 4.7 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DEC1 PF15859.5 PVD27161.1 - 0.049 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family MLANA PF14991.6 PVD27161.1 - 0.078 13.3 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein melan-A DUF1096 PF06493.11 PVD27161.1 - 6.2 7.4 8.2 0.35 11.4 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1096) DAG1 PF05454.11 PVD27162.1 - 0.0004 19.9 0.4 0.00078 18.9 0.4 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 PVD27162.1 - 0.0019 18.1 1.3 0.0027 17.6 0.1 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 PVD27162.1 - 0.017 15.1 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RIFIN PF02009.16 PVD27162.1 - 0.027 14.4 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 PVD27162.1 - 0.055 13.4 0.4 0.094 12.6 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 PVD27162.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Tetraspanin PF00335.20 PVD27162.1 - 0.11 12.2 1.2 0.14 11.9 1.2 1.4 1 1 0 1 1 1 0 Tetraspanin family TMEM51 PF15345.6 PVD27162.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FeoB_associated PF12669.7 PVD27162.1 - 0.12 12.7 4.8 0.32 11.4 4.8 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5305 PF17231.2 PVD27162.1 - 0.2 11.0 3.7 0.068 12.6 1.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF3377 PF11857.8 PVD27163.1 - 0.061 13.3 0.7 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Profilin PF00235.19 PVD27164.1 - 0.00017 21.8 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Profilin COMM_domain PF07258.14 PVD27166.1 - 0.033 14.3 2.1 4.4 7.5 0.2 2.7 2 0 0 2 2 2 0 COMM domain DUF1664 PF07889.12 PVD27166.1 - 4.4 7.4 7.4 1.5 8.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PH_16 PF17838.1 PVD27167.1 - 9.5e-44 148.2 0.0 1.7e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 PVD27167.1 - 1.4e-32 113.5 1.3 2.3e-32 112.7 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain C1_1 PF00130.22 PVD27167.1 - 2.8e-12 46.3 4.2 6.7e-12 45.1 4.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_13 PF16652.5 PVD27167.1 - 1.1e-06 28.6 0.1 1.1e-06 28.6 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 PVD27167.1 - 0.00069 20.1 0.1 0.0041 17.6 0.0 2.3 2 0 0 2 2 2 1 PH domain SR-25 PF10500.9 PVD27167.1 - 0.022 14.4 7.6 0.059 13.0 7.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein C1_2 PF03107.16 PVD27167.1 - 0.28 11.5 3.3 0.69 10.3 3.3 1.7 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 PVD27167.1 - 0.43 10.9 4.5 1.1 9.7 4.5 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 PVD27167.1 - 0.73 9.8 4.3 1.8 8.5 4.3 1.7 1 0 0 1 1 1 0 PHD-finger OAF PF14941.6 PVD27168.1 - 8.6e-56 189.1 0.2 1.2e-55 188.6 0.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator, Out at first MFS_1 PF07690.16 PVD27168.1 - 1.3e-41 142.7 44.2 2.8e-34 118.6 19.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PVD27168.1 - 0.0047 15.3 7.6 0.061 11.6 0.7 3.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Ldl_recept_a PF00057.18 PVD27169.1 - 4.7e-11 42.7 32.8 5.8e-07 29.6 3.6 4.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD27169.1 - 0.0021 18.8 0.0 0.0042 17.8 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD27170.1 - 8.3e-22 77.1 53.4 1.2e-06 28.6 2.6 6.0 5 1 0 5 5 5 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27170.1 - 1.3e-18 66.5 9.6 7.9e-08 31.9 0.3 4.8 4 1 1 5 5 5 3 Leucine rich repeat 7tm_1 PF00001.21 PVD27170.1 - 5.4e-09 35.8 10.6 5.6e-09 35.7 9.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 PVD27170.1 - 8.4e-09 35.6 9.9 0.0015 18.9 0.4 4.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD27170.1 - 1.4e-05 24.9 0.9 37 5.4 0.0 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD27170.1 - 0.00081 19.2 3.5 0.74 10.0 0.3 4.9 4 0 0 4 4 4 1 Leucine Rich repeat Toxin_27 PF08099.11 PVD27170.1 - 0.42 10.8 4.6 5.3 7.2 1.6 3.3 2 0 0 2 2 2 0 Scorpion calcine family Ldl_recept_a PF00057.18 PVD27171.1 - 3.5e-08 33.5 50.1 9.8e-07 28.9 3.7 6.0 6 0 0 6 6 6 3 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD27171.1 - 0.012 16.3 0.2 0.033 14.9 0.2 1.8 1 1 0 1 1 1 0 Lectin C-type domain Ldl_recept_a PF00057.18 PVD27172.1 - 6.1e-23 80.8 49.6 7.9e-07 29.2 2.6 4.9 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27172.1 - 4.3e-07 29.6 0.2 1.2e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat 7tm_1 PF00001.21 PVD27172.1 - 0.0012 18.3 1.6 0.0012 18.3 1.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Toxin_27 PF08099.11 PVD27172.1 - 0.0029 17.7 5.1 0.043 13.9 2.0 3.2 2 0 0 2 2 2 1 Scorpion calcine family Podovirus_Gp16 PF05894.12 PVD27172.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) LRR_4 PF12799.7 PVD27172.1 - 0.048 14.1 0.2 0.2 12.2 0.5 1.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD27172.1 - 0.13 12.9 0.4 0.97 10.2 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_5 PF13306.6 PVD27172.1 - 0.19 11.7 1.0 0.36 10.8 0.1 1.9 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Ldl_recept_a PF00057.18 PVD27173.1 - 2.5e-22 78.8 50.1 4.2e-08 33.3 8.9 5.0 6 0 0 6 6 6 4 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD27174.1 - 5.6e-20 71.3 37.2 6.1e-08 32.7 3.3 3.3 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Toxin_27 PF08099.11 PVD27174.1 - 0.62 10.2 8.8 0.86 9.8 1.1 3.1 3 0 0 3 3 3 0 Scorpion calcine family Ig_3 PF13927.6 PVD27175.1 - 2.1e-20 73.1 9.9 3.2e-15 56.5 0.4 3.5 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27175.1 - 2.2e-16 59.9 3.9 5.2e-11 42.7 0.4 2.6 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD27175.1 - 1.2e-12 47.7 6.7 1.1e-06 28.6 0.2 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27175.1 - 8e-12 45.2 8.7 1.7e-06 28.1 0.1 2.9 3 0 0 3 3 2 2 Immunoglobulin domain I-set PF07679.16 PVD27175.1 - 3.5e-11 43.0 0.0 4.5e-08 33.1 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain SKG6 PF08693.10 PVD27175.1 - 2.5e-09 36.4 8.3 5.8e-09 35.2 8.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain V-set PF07686.17 PVD27175.1 - 2.6e-07 30.8 3.7 0.0026 17.9 0.1 3.6 2 1 1 3 3 3 1 Immunoglobulin V-set domain TMEM154 PF15102.6 PVD27175.1 - 7.2e-07 29.2 1.8 7.2e-07 29.2 1.8 1.7 2 0 0 2 2 1 1 TMEM154 protein family Glycophorin_A PF01102.18 PVD27175.1 - 0.00014 22.0 1.0 0.00014 22.0 1.0 1.9 2 0 0 2 2 2 1 Glycophorin A Herpes_gE PF02480.16 PVD27175.1 - 0.00023 20.1 0.1 0.00037 19.4 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Ig_5 PF16681.5 PVD27175.1 - 0.0003 21.1 0.1 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Shisa PF13908.6 PVD27175.1 - 0.00065 20.0 0.5 0.00065 20.0 0.5 1.9 2 0 0 2 2 1 1 Wnt and FGF inhibitory regulator RIFIN PF02009.16 PVD27175.1 - 0.00077 19.5 0.4 0.0012 18.8 0.4 1.2 1 0 0 1 1 1 1 Rifin DUF3827 PF12877.7 PVD27175.1 - 0.00077 18.0 1.7 0.0012 17.3 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Ig_4 PF16680.5 PVD27175.1 - 0.001 19.3 0.2 0.0065 16.7 0.0 2.3 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain DUF4448 PF14610.6 PVD27175.1 - 0.0016 18.2 0.2 0.0031 17.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) C1-set PF07654.15 PVD27175.1 - 0.0032 17.8 3.1 2.1 8.8 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin C1-set domain EphA2_TM PF14575.6 PVD27175.1 - 0.0038 18.1 0.0 0.01 16.7 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 PVD27175.1 - 0.007 16.2 1.3 0.017 15.0 0.7 1.9 2 0 0 2 2 1 1 Endothelial cell-specific chemotaxis regulator Mid2 PF04478.12 PVD27175.1 - 0.0098 15.7 2.4 0.025 14.4 2.4 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Metallothio_Cad PF07846.11 PVD27175.1 - 0.012 15.7 0.2 0.04 14.0 0.2 1.9 1 0 0 1 1 1 0 Metallothionein family DUF5305 PF17231.2 PVD27175.1 - 0.027 13.9 0.8 0.052 12.9 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 PVD27175.1 - 0.029 13.1 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 PVD27175.1 - 0.042 14.0 4.5 0.2 11.8 5.2 1.8 2 0 0 2 2 1 0 Podoplanin Amnionless PF14828.6 PVD27175.1 - 0.042 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 PVD27175.1 - 0.047 14.0 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 PVD27175.1 - 0.048 13.4 8.7 0.085 12.6 8.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRRC37AB_C PF14914.6 PVD27175.1 - 0.062 13.2 0.1 0.099 12.6 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Insulin_TMD PF17870.1 PVD27175.1 - 0.17 11.9 5.0 0.31 11.1 5.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 PVD27175.1 - 1.2 9.1 3.3 2.5 8.1 3.3 1.4 1 0 0 1 1 1 0 Syndecan domain Ig_3 PF13927.6 PVD27176.1 - 8.4e-21 74.4 8.9 7e-15 55.4 0.5 4.6 4 0 0 4 4 4 2 Immunoglobulin domain Ldl_recept_a PF00057.18 PVD27176.1 - 8.1e-18 64.4 57.0 9.9e-05 22.5 0.4 6.4 6 0 0 6 6 6 5 Low-density lipoprotein receptor domain class A ig PF00047.25 PVD27176.1 - 1.3e-12 47.7 9.0 6.3e-06 26.3 0.1 3.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27176.1 - 1.5e-12 47.6 17.7 3.9e-09 36.7 0.5 4.5 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD27176.1 - 1.3e-11 44.4 0.1 6.5e-08 32.5 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 PVD27176.1 - 2.8e-11 43.3 2.5 1.7e-06 28.0 0.7 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27176.1 - 1.7e-06 28.1 10.2 0.011 15.9 0.1 4.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain Lectin_C PF00059.21 PVD27176.1 - 0.00016 22.4 0.0 0.00016 22.4 0.0 2.6 3 0 0 3 3 2 1 Lectin C-type domain LRR_8 PF13855.6 PVD27176.1 - 0.0012 18.6 3.1 0.0072 16.1 1.2 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PVD27176.1 - 0.032 14.6 1.0 0.14 12.6 1.0 2.2 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) C1-set PF07654.15 PVD27176.1 - 0.1 13.0 2.9 3 8.3 0.3 3.7 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_4 PF16680.5 PVD27176.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.7 3 0 0 3 3 2 0 T-cell surface glycoprotein CD3 delta chain Ldl_recept_a PF00057.18 PVD27177.1 - 1.8e-12 47.2 23.7 1.4e-06 28.4 15.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PTCB-BRCT PF12738.7 PVD27177.1 - 0.18 11.8 0.0 0.99 9.4 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain Ldl_recept_a PF00057.18 PVD27178.1 - 0.036 14.3 2.0 0.17 12.1 2.0 2.2 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ank_4 PF13637.6 PVD27179.1 - 4.8e-14 52.5 1.8 3.8e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27179.1 - 2.2e-10 40.6 1.2 3.6e-05 23.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27179.1 - 3.2e-10 40.4 0.8 0.00021 21.8 0.3 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD27179.1 - 8.4e-09 35.0 1.9 0.065 13.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PVD27179.1 - 1e-08 35.2 2.6 0.052 14.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Alfin PF12165.8 PVD27179.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Alfin MCC-bdg_PDZ PF10506.9 PVD27179.1 - 0.11 12.5 0.9 4.3 7.4 0.1 2.6 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ldl_recept_a PF00057.18 PVD27180.1 - 4.5e-17 62.0 50.7 2.8e-05 24.3 2.2 5.7 5 1 0 5 5 5 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27180.1 - 1.8e-12 46.8 7.7 1.3e-07 31.2 0.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD27180.1 - 9.6e-06 25.9 2.9 9.5e-05 22.7 0.4 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD27180.1 - 0.0082 16.1 1.1 1.1 9.5 0.1 3.5 3 0 0 3 3 3 1 Leucine Rich repeat PRKCSH-like PF12999.7 PVD27180.1 - 0.0083 15.9 14.0 0.0083 15.9 14.0 3.3 2 1 2 4 4 4 1 Glucosidase II beta subunit-like LRR_1 PF00560.33 PVD27180.1 - 0.04 14.4 1.9 23 6.0 0.1 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat Ldl_recept_a PF00057.18 PVD27181.1 - 9.1e-19 67.4 54.0 9e-06 25.8 11.4 5.6 5 1 0 5 5 5 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27181.1 - 4e-08 32.9 1.6 4.1e-07 29.7 2.6 2.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PVD27181.1 - 4.1e-07 30.2 0.8 4.1e-07 30.2 0.8 2.6 2 1 1 4 4 4 1 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 PVD27181.1 - 0.0048 16.3 0.1 0.0087 15.4 0.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.6 PVD27181.1 - 0.015 15.3 0.1 0.57 10.4 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 PVD27181.1 - 0.026 15.0 1.6 24 6.0 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 PVD27181.1 - 0.14 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Ldl_recept_a PF00057.18 PVD27182.1 - 2.5e-12 46.8 20.0 4.9e-07 29.9 8.5 3.4 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD27182.1 - 1.1e-06 29.3 0.0 1.3e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Lectin C-type domain PRKCSH-like PF12999.7 PVD27182.1 - 1.2 8.9 14.2 5.7 6.7 14.0 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 PVD27183.1 - 3.1e-21 75.3 61.1 1.2e-06 28.6 3.7 6.3 6 0 0 6 6 6 5 Low-density lipoprotein receptor domain class A LRR_4 PF12799.7 PVD27183.1 - 4e-07 30.3 12.9 0.00013 22.2 4.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD27183.1 - 9.7e-07 28.5 1.0 2.6e-06 27.1 1.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 PVD27183.1 - 0.033 14.7 0.7 2.3 9.1 0.6 3.7 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD27183.1 - 0.062 13.4 1.4 2.6 8.3 0.5 2.9 2 0 0 2 2 2 0 Leucine Rich repeat Ldl_recept_a PF00057.18 PVD27184.1 - 1.8e-11 44.0 35.7 0.00011 22.4 14.2 4.7 4 1 1 5 5 5 3 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27184.1 - 6.2e-09 35.5 2.5 2.4e-08 33.6 2.5 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD27184.1 - 2.1e-06 27.9 6.0 0.00089 19.6 1.1 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 PVD27184.1 - 0.013 16.3 1.8 0.016 15.9 0.0 2.1 2 0 0 2 2 2 0 Lectin C-type domain LRR_1 PF00560.33 PVD27184.1 - 0.038 14.5 1.0 26 5.9 0.2 3.9 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD27184.1 - 0.19 11.9 2.0 8.8 6.7 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Ldl_recept_a PF00057.18 PVD27185.1 - 6.3e-13 48.7 31.0 9e-05 22.6 14.2 4.4 3 1 1 4 4 4 3 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD27185.1 - 4.1e-09 36.1 2.6 1.4e-08 34.4 2.6 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD27185.1 - 9.3e-08 32.3 5.1 0.00012 22.4 0.6 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 PVD27185.1 - 8.5e-05 23.2 0.0 8.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Lectin C-type domain LRR_1 PF00560.33 PVD27185.1 - 0.024 15.1 1.1 22 6.1 0.2 4.0 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD27185.1 - 0.12 12.5 2.2 7.4 6.9 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Lectin_C PF00059.21 PVD27186.1 - 0.0011 19.6 0.2 0.0033 18.1 0.1 1.9 2 1 0 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD27186.1 - 0.11 12.7 0.7 0.11 12.7 0.7 2.3 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Keratin_B2 PF01500.17 PVD27188.1 - 0.012 15.6 34.1 0.084 12.9 20.0 2.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein CPG4 PF15481.6 PVD27188.1 - 0.035 14.7 17.8 0.42 11.3 0.6 4.2 1 1 2 4 4 4 0 Chondroitin proteoglycan 4 Baculo_PEP_C PF04513.12 PVD27188.1 - 0.12 12.4 1.8 15 5.6 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.27 PVD27189.1 - 2e-31 109.3 0.0 2.7e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ald_deCOase PF11266.8 PVD27189.1 - 0.2 11.4 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase AIG1 PF04548.16 PVD27190.1 - 2e-52 177.6 4.4 2.7e-52 177.2 0.0 2.7 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD27190.1 - 1e-05 25.6 0.0 1e-05 25.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase DDE_Tnp_1_7 PF13843.6 PVD27190.1 - 0.00057 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Transposase IS4 FeoB_N PF02421.18 PVD27190.1 - 0.011 15.2 0.1 0.033 13.7 0.1 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B BAH PF01426.18 PVD27190.1 - 0.017 15.0 0.0 0.075 12.9 0.0 1.9 1 1 0 1 1 1 0 BAH domain TetR PF13972.6 PVD27190.1 - 0.017 14.8 0.5 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 Bacterial transcriptional repressor ApoA-II PF04711.13 PVD27190.1 - 0.025 14.7 6.7 0.31 11.2 3.6 2.5 1 1 1 2 2 2 0 Apolipoprotein A-II (ApoA-II) AAA_7 PF12775.7 PVD27190.1 - 0.042 13.4 0.2 0.11 12.0 0.2 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 PVD27190.1 - 0.057 12.5 0.4 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Nup88 PF10168.9 PVD27190.1 - 0.61 7.8 23.4 0.97 7.2 23.4 1.2 1 0 0 1 1 1 0 Nuclear pore component RsgA_GTPase PF03193.16 PVD27190.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.8 2 1 1 3 3 2 0 RsgA GTPase LMBR1 PF04791.16 PVD27190.1 - 2.2 7.1 13.5 0.96 8.3 10.4 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 PVD27190.1 - 8.9 5.8 14.4 14 5.2 11.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF948 PF06103.11 PVD27190.1 - 9.2 6.6 6.8 64 3.9 6.7 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EphA2_TM PF14575.6 PVD27193.1 - 0.12 13.3 0.0 0.28 12.1 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD27194.1 - 0.0056 16.6 1.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family DUF5385 PF17359.2 PVD27194.1 - 0.0086 15.7 0.2 0.022 14.3 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Peptidase_S49_N PF08496.10 PVD27194.1 - 0.014 15.5 0.9 0.02 14.9 0.1 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SIT PF15330.6 PVD27194.1 - 0.024 15.1 0.2 0.99 9.9 0.0 2.6 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Tetraspanin PF00335.20 PVD27194.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Orbi_VP2 PF00898.17 PVD27194.1 - 0.042 11.6 0.0 0.067 10.9 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 EphA2_TM PF14575.6 PVD27194.1 - 0.088 13.7 0.3 0.24 12.3 0.3 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 PVD27194.1 - 0.096 12.5 0.7 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FeoB_associated PF12669.7 PVD27194.1 - 4.1 7.9 4.9 1.8 9.0 1.5 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Insulin_TMD PF17870.1 PVD27194.1 - 8.3 6.6 6.4 33 4.7 6.4 2.0 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 PVD27195.1 - 7.6e-06 25.9 0.8 1.2e-05 25.2 0.8 1.4 1 1 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 PVD27195.1 - 1.6e-05 25.0 0.0 1.9e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Rifin LRRC37AB_C PF14914.6 PVD27195.1 - 9.4e-05 22.4 0.2 0.00016 21.6 0.2 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Shisa PF13908.6 PVD27195.1 - 0.0031 17.8 0.1 0.0054 17.0 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Saf_2TM PF18303.1 PVD27195.1 - 0.0039 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain DAG1 PF05454.11 PVD27195.1 - 0.0048 16.3 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2207 PF09972.9 PVD27195.1 - 0.0057 15.5 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Orf78 PF06024.12 PVD27195.1 - 0.0067 16.7 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) BatD PF13584.6 PVD27195.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance EphA2_TM PF14575.6 PVD27195.1 - 0.024 15.5 2.0 0.038 14.9 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.6 PVD27195.1 - 0.031 14.3 0.2 0.062 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3377 PF11857.8 PVD27195.1 - 0.037 13.9 0.3 0.077 12.9 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF3377) SID-1_RNA_chan PF13965.6 PVD27195.1 - 0.039 12.4 0.1 0.049 12.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MLANA PF14991.6 PVD27195.1 - 0.049 13.9 0.7 1.3 9.3 0.1 2.5 2 1 1 3 3 3 0 Protein melan-A GEN1_C PF18380.1 PVD27195.1 - 0.058 14.3 0.3 0.12 13.2 0.3 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Peptidase_S49_N PF08496.10 PVD27195.1 - 0.067 13.3 2.8 0.56 10.3 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CCD PF07860.11 PVD27195.1 - 0.082 12.9 4.0 0.33 11.0 0.2 2.6 2 1 1 3 3 3 0 WisP family C-Terminal Region ECSCR PF15820.5 PVD27195.1 - 0.1 12.4 3.3 0.17 11.7 2.9 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF872 PF05915.12 PVD27195.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Syndecan PF01034.20 PVD27195.1 - 0.18 11.8 1.6 0.36 10.8 1.6 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 PVD27195.1 - 0.29 11.8 1.7 0.5 11.0 0.4 1.9 1 1 1 2 2 2 0 Small Novel Rich in Cartilage FeoB_associated PF12669.7 PVD27195.1 - 1.4 9.4 5.2 0.53 10.7 2.2 1.9 2 0 0 2 2 1 0 FeoB-associated Cys-rich membrane protein SIT PF15330.6 PVD27195.1 - 2.1 8.8 5.7 0.57 10.6 0.2 2.4 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT WRNPLPNID PF15017.6 PVD27195.1 - 2.9 8.9 7.1 0.47 11.4 3.4 1.6 2 0 0 2 2 1 0 Putative WW-binding domain and destruction box LAX PF15681.5 PVD27195.1 - 6.5 5.5 9.1 0.27 10.0 1.6 1.9 1 1 1 2 2 2 0 Lymphocyte activation family X NVEALA PF14055.6 PVD27195.1 - 8.7 6.4 9.5 8.5 6.4 0.3 3.0 4 0 0 4 4 3 0 NVEALA protein DIL PF01843.19 PVD27196.1 - 0.075 13.3 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 DIL domain Sid-5 PF17204.3 PVD27201.1 - 0.11 12.7 0.2 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Sid-5 family Ada_Zn_binding PF02805.16 PVD27203.1 - 0.081 13.0 0.6 0.85 9.7 0.5 2.3 2 0 0 2 2 2 0 Metal binding domain of Ada FAM176 PF14851.6 PVD27204.1 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.3 1 1 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 PVD27204.1 - 0.046 14.6 0.0 0.086 13.7 0.0 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2749 PF10907.8 PVD27204.1 - 0.046 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) CD34_antigen PF06365.12 PVD27204.1 - 0.051 13.2 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Myc_target_1 PF15179.6 PVD27204.1 - 0.086 12.7 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 Mid2 PF04478.12 PVD27204.1 - 0.36 10.6 1.7 0.52 10.1 1.1 1.4 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 PVD27204.1 - 3.7 7.0 11.5 7.4 6.1 11.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2852 PF11014.8 PVD27205.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) TMEM154 PF15102.6 PVD27206.1 - 0.0038 17.1 1.2 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF4519 PF15012.6 PVD27206.1 - 0.0083 16.3 1.2 0.017 15.3 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) Stevor PF17410.2 PVD27206.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 PVD27206.1 - 0.02 14.7 0.4 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 PVD27206.1 - 0.071 14.0 0.0 0.13 13.2 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 PVD27206.1 - 0.11 11.9 10.4 0.26 10.7 10.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 PVD27206.1 - 0.11 12.5 0.7 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RVT_1 PF00078.27 PVD27210.1 - 0.00027 20.5 0.1 0.00033 20.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNOBA PF07701.14 PVD27210.1 - 0.025 14.0 0.2 0.03 13.7 0.2 1.1 1 0 0 1 1 1 0 Heme NO binding associated Neur_chan_memb PF02932.16 PVD27211.1 - 1.5 8.8 4.1 2 8.4 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Adeno_E3_CR2 PF02439.15 PVD27212.1 - 0.0035 17.1 1.1 0.006 16.3 1.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Dicty_REP PF05086.12 PVD27213.1 - 3.2 5.6 16.5 4.2 5.2 16.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein rve PF00665.26 PVD27214.1 - 7.5e-20 71.3 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 PVD27214.1 - 7.5e-16 58.0 0.5 1.7e-15 56.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD27214.1 - 0.00023 21.3 0.5 0.00062 19.9 0.5 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF155 PF02582.14 PVD27214.1 - 0.09 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Ank_3 PF13606.6 PVD27215.1 - 2e-18 64.6 6.3 0.001 19.4 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PVD27215.1 - 3.2e-17 62.3 8.1 0.00011 22.4 0.0 6.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27215.1 - 2.8e-15 56.7 5.7 0.0028 18.2 0.2 4.8 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD27215.1 - 6.9e-14 52.0 10.1 5.1e-06 26.9 0.1 6.4 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD27215.1 - 6.3e-12 45.4 11.5 0.00085 19.7 0.0 7.1 6 1 1 7 7 7 4 Ankyrin repeat Protocadherin PF08374.11 PVD27216.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DUF4083 PF13314.6 PVD27216.1 - 0.031 14.2 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3139 PF11337.8 PVD27216.1 - 0.12 13.1 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF3827 PF12877.7 PVD27218.1 - 0.0011 17.4 0.5 0.0016 17.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) DUF3377 PF11857.8 PVD27218.1 - 0.0087 16.0 1.2 0.018 15.0 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.6 PVD27218.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 PVD27218.1 - 0.032 14.1 0.5 0.032 14.1 0.5 1.7 2 0 0 2 2 2 0 Rifin SP_C-Propep PF08999.10 PVD27218.1 - 0.045 13.5 0.4 0.084 12.7 0.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF5305 PF17231.2 PVD27218.1 - 0.064 12.7 0.1 0.064 12.7 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) SKG6 PF08693.10 PVD27218.1 - 0.08 12.4 8.1 0.19 11.1 8.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 PVD27218.1 - 0.14 12.2 5.5 0.26 11.4 5.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2897 PF11446.8 PVD27218.1 - 2.9 7.9 6.5 7.7 6.5 6.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Mid2 PF04478.12 PVD27219.1 - 0.0052 16.6 0.1 0.0081 16.0 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor FeoB_associated PF12669.7 PVD27219.1 - 0.063 13.7 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Chordopox_A13L PF05961.11 PVD27219.1 - 0.071 13.4 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SARAF PF06682.12 PVD27219.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 PVD27219.1 - 0.11 12.2 3.2 0.19 11.5 3.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5385 PF17359.2 PVD27219.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 PVD27219.1 - 0.14 11.6 0.3 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CBP_BcsF PF11120.8 PVD27219.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF SKG6 PF08693.10 PVD27220.1 - 0.00045 19.6 1.5 0.00099 18.5 1.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PFK PF00365.20 PVD27220.1 - 0.014 14.7 0.2 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Phosphofructokinase Rax2 PF12768.7 PVD27220.1 - 0.025 14.1 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Sarcoglycan_2 PF05510.13 PVD27220.1 - 0.063 12.0 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Syndecan PF01034.20 PVD27220.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Chordopox_A13L PF05961.11 PVD27220.1 - 0.085 13.1 0.3 0.17 12.1 0.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Glycophorin_A PF01102.18 PVD27220.1 - 0.091 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 PVD27220.1 - 0.1 13.5 0.0 0.23 12.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RVT_1 PF00078.27 PVD27221.1 - 3e-21 76.0 0.1 5.1e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_2 PF08356.12 PVD27221.1 - 0.042 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 EF hand associated PH PF00169.29 PVD27222.1 - 3.3e-14 53.3 1.1 1.6e-13 51.0 0.4 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 PVD27222.1 - 0.0058 16.9 0.2 0.015 15.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain FHA PF00498.26 PVD27222.1 - 0.077 13.4 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 FHA domain PH_11 PF15413.6 PVD27222.1 - 3.4 8.2 8.1 0.22 12.0 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain A_deaminase PF00962.22 PVD27223.1 - 5e-121 404.0 0.0 1.2e-120 402.8 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase zf-CCCH_6 PF18585.1 PVD27223.1 - 0.007 16.2 0.5 0.24 11.3 0.1 2.6 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 H_lectin PF09458.10 PVD27224.1 - 3.6e-05 23.9 0.6 7.3e-05 22.9 0.2 1.8 2 0 0 2 2 2 1 H-type lectin domain Colicin_V PF02674.16 PVD27224.1 - 0.0079 16.2 1.1 0.012 15.6 1.1 1.2 1 0 0 1 1 1 1 Colicin V production protein Abhydrolase_9_N PF15420.6 PVD27225.1 - 0.12 12.4 2.7 0.18 11.8 2.7 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus LapA_dom PF06305.11 PVD27225.1 - 0.21 11.4 0.3 0.48 10.3 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mobilization_B PF17511.2 PVD27226.1 - 0.27 11.6 6.1 2.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Mobilization protein B Nucleocapsid-N PF11030.8 PVD27227.1 - 0.16 11.9 20.0 1.1 9.2 0.5 4.0 1 1 2 4 4 4 0 Nucleocapsid protein N SAM_Exu PF18609.1 PVD27230.1 - 0.12 12.5 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Exuperantia SAM-like domain T3SSipB PF16535.5 PVD27230.1 - 0.12 12.8 1.9 0.16 12.4 1.9 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB CALM_bind PF16025.5 PVD27230.1 - 0.56 10.7 2.8 1.9 9.0 2.7 1.9 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Shal-type PF11601.8 PVD27231.1 - 0.0026 17.2 1.4 20 4.8 0.0 4.3 5 0 0 5 5 5 3 Shal-type voltage-gated potassium channels, N-terminal Mobilization_B PF17511.2 PVD27231.1 - 0.064 13.6 8.3 2.6 8.4 1.2 3.3 1 1 2 3 3 3 0 Mobilization protein B DUF2303 PF10065.9 PVD27232.1 - 4.5 6.3 7.8 12 4.9 1.8 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2303) Ribosomal_S19e PF01090.19 PVD27233.1 - 1.4e-56 190.0 0.0 1.7e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e TAP_C PF03943.13 PVD27233.1 - 0.22 11.2 0.2 2 8.1 0.0 2.1 2 0 0 2 2 2 0 TAP C-terminal domain Mobilization_B PF17511.2 PVD27234.1 - 0.26 11.7 2.0 0.45 10.9 1.4 1.7 1 1 1 2 2 2 0 Mobilization protein B zf-dskA_traR PF01258.17 PVD27234.1 - 1.6 8.8 11.3 4.1 7.4 0.0 4.9 6 0 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger Phostensin_N PF13916.6 PVD27234.1 - 3.4 8.1 12.9 4.2 7.8 0.7 2.9 1 1 2 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Exo_endo_phos_2 PF14529.6 PVD27236.1 - 4.5e-18 65.2 0.2 1.9e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD27236.1 - 2.3e-15 56.8 0.3 5.4e-15 55.5 0.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MutS_IV PF05190.18 PVD27236.1 - 0.028 14.7 0.1 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV DUF1932 PF09130.11 PVD27236.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Streptin-Immun PF11083.8 PVD27236.1 - 0.083 13.3 0.2 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein AAA_8 PF12780.7 PVD27237.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 HGD-D PF06050.13 PVD27237.1 - 0.077 12.8 0.1 0.083 12.6 0.1 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF1641 PF07849.11 PVD27237.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4574 PF15141.6 PVD27237.1 - 2.3 8.2 4.3 0.84 9.6 1.1 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 GTF2I PF02946.14 PVD27238.1 - 6.7e-11 42.1 0.1 1.4e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 GTF2I-like repeat Baculo_PEP_C PF04513.12 PVD27238.1 - 0.051 13.6 0.3 0.099 12.7 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 PVD27238.1 - 0.072 13.2 0.3 0.22 11.6 0.3 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF600 PF04634.12 PVD27238.1 - 0.076 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DUF1664 PF07889.12 PVD27238.1 - 0.63 10.1 5.2 0.2 11.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S19e PF01090.19 PVD27240.1 - 5.9e-57 191.2 0.0 6.8e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e TAP_C PF03943.13 PVD27240.1 - 0.1 12.3 0.2 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 TAP C-terminal domain HTH_IclR PF09339.10 PVD27240.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain IF3_C PF00707.22 PVD27240.1 - 0.13 12.2 0.1 7.8 6.5 0.0 2.7 2 1 1 3 3 3 0 Translation initiation factor IF-3, C-terminal domain Ig_3 PF13927.6 PVD27243.1 - 2.2e-14 53.8 9.9 8.1e-09 36.0 0.3 4.5 4 2 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27243.1 - 2.5e-14 53.4 1.3 2.1e-08 34.4 0.2 4.3 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 PVD27243.1 - 3.2e-14 52.9 7.6 2.6e-08 33.9 0.5 4.9 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD27243.1 - 1.5e-11 44.2 0.3 8.5e-09 35.4 0.1 4.1 5 0 0 5 5 4 1 Immunoglobulin I-set domain V-set PF07686.17 PVD27243.1 - 5.5e-10 39.4 2.9 0.1 12.8 0.0 4.8 4 1 1 5 5 5 2 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD27243.1 - 2.5e-05 24.6 1.5 0.00022 21.6 0.1 3.0 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 PVD27243.1 - 5.8e-05 23.1 3.4 0.15 12.1 0.1 3.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 PVD27243.1 - 0.0011 19.1 0.3 0.0078 16.5 0.1 2.5 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD27243.1 - 0.027 14.0 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Glycophorin_A PF01102.18 PVD27243.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Izumo-Ig PF16706.5 PVD27243.1 - 0.06 13.4 0.1 0.36 10.9 0.0 2.2 3 0 0 3 3 2 0 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD27243.1 - 0.062 13.1 0.0 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Ig_3 PF13927.6 PVD27244.1 - 0.0015 19.1 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD27244.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 PVD27244.1 - 0.016 15.3 0.0 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 PVD27244.1 - 0.097 12.7 0.0 2.4 8.3 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin I-set domain Ank_2 PF12796.7 PVD27245.1 - 8.1e-20 71.2 0.1 5.8e-10 39.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27245.1 - 2e-17 62.7 0.5 3.6e-06 27.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD27245.1 - 1.6e-13 49.5 3.3 3.3e-06 27.0 0.0 5.3 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PVD27245.1 - 3.2e-12 46.7 2.0 5.4e-05 23.7 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27245.1 - 1e-09 38.5 1.9 0.001 19.4 0.0 4.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) DUF4247 PF14042.6 PVD27245.1 - 5.2 7.8 7.3 12 6.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4247) Selenoprotein_S PF06936.11 PVD27246.1 - 3.8e-26 92.1 4.6 4.3e-26 91.9 4.6 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) DUF4238 PF14022.6 PVD27246.1 - 0.041 13.4 0.3 0.047 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF4407 PF14362.6 PVD27246.1 - 0.048 13.0 1.1 0.058 12.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4349 PF14257.6 PVD27246.1 - 0.34 10.3 3.8 0.24 10.8 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2721 PF11026.8 PVD27246.1 - 2 8.3 3.1 1.1 9.2 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) SMP_2 PF10144.9 PVD27247.1 - 0.047 13.3 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUF4437 PF14499.6 PVD27247.1 - 0.069 12.3 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Ank_2 PF12796.7 PVD27248.1 - 1.1e-26 93.2 0.1 4.5e-15 56.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD27248.1 - 7.5e-24 83.8 0.1 1.3e-09 38.4 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27248.1 - 1.4e-22 79.4 4.6 4.8e-09 36.3 0.1 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD27248.1 - 1.5e-21 74.2 0.8 2.3e-05 24.4 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 PVD27248.1 - 2.6e-19 68.7 2.3 0.00048 20.5 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat IFT46_B_C PF12317.8 PVD27249.1 - 2.6e-100 334.5 1.3 3.3e-100 334.2 1.3 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal RXT2_N PF08595.11 PVD27249.1 - 0.0089 16.1 2.7 0.016 15.2 2.7 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 PVD27249.1 - 0.027 14.8 9.3 0.053 13.9 9.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 PVD27249.1 - 0.082 12.6 2.9 0.18 11.4 2.9 1.6 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 PVD27249.1 - 0.12 12.1 9.9 0.21 11.3 9.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PVD27249.1 - 0.49 9.7 9.3 0.72 9.1 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 PVD27249.1 - 0.51 10.2 6.2 0.16 11.8 3.3 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 PVD27249.1 - 0.58 8.2 9.2 0.91 7.5 9.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 PVD27249.1 - 0.93 9.0 5.8 1.1 8.8 3.0 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 PVD27249.1 - 6.1 7.1 10.1 0.99 9.7 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3245 PF11595.8 PVD27249.1 - 7.2 7.1 12.5 16 6.0 12.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) Nas2_N PF18265.1 PVD27250.1 - 4.6e-33 113.0 0.2 6.7e-33 112.5 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 PVD27250.1 - 5e-08 33.1 0.0 8.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD27250.1 - 1e-07 31.7 0.8 1.8e-07 30.9 0.8 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD27250.1 - 1.7e-06 28.3 0.1 3.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 PVD27250.1 - 0.0069 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain TPR_1 PF00515.28 PVD27251.1 - 2.2e-42 141.2 15.4 1.7e-08 33.9 0.1 9.6 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 PVD27251.1 - 9.1e-37 122.2 15.8 1.5e-05 24.7 0.0 10.5 12 0 0 12 12 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 PVD27251.1 - 1.2e-31 108.1 0.2 4.3e-06 26.3 0.1 8.0 5 3 3 8 8 8 5 TPR repeat TPR_8 PF13181.6 PVD27251.1 - 1.2e-27 93.8 14.5 0.00016 21.7 0.1 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 PVD27251.1 - 5.5e-21 73.5 3.8 0.11 13.4 0.0 10.4 4 2 5 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 PVD27251.1 - 9.8e-19 67.4 11.0 0.00093 19.4 0.0 6.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 PVD27251.1 - 1e-17 63.1 8.7 0.074 13.5 0.0 9.5 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 PVD27251.1 - 2.1e-16 60.3 0.0 6e-05 23.6 0.0 6.4 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD27251.1 - 2.1e-14 52.4 4.1 0.0014 18.5 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD27251.1 - 7e-13 48.5 3.0 0.0052 16.9 0.3 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD27251.1 - 3.3e-12 46.7 13.8 0.00095 19.6 0.0 6.9 6 2 1 7 7 7 4 Tetratricopeptide repeat NARP1 PF12569.8 PVD27251.1 - 4.1e-08 32.6 6.5 0.02 13.8 0.0 3.5 2 1 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 PVD27251.1 - 1.9e-06 28.2 14.1 2 9.2 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD27251.1 - 2.1e-06 27.9 8.3 0.0023 18.1 0.2 5.2 4 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 PVD27251.1 - 0.0011 18.4 7.6 0.0013 18.2 1.0 3.2 2 2 2 4 4 4 1 MalT-like TPR region MAS20 PF02064.15 PVD27251.1 - 0.0016 18.5 3.3 6.5 6.9 0.0 4.6 4 1 0 4 4 4 1 MAS20 protein import receptor TPR_21 PF09976.9 PVD27251.1 - 0.0018 18.1 17.5 0.0021 17.8 2.3 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat-like domain PPR PF01535.20 PVD27251.1 - 0.003 17.7 1.3 5.3 7.5 0.0 4.5 4 0 0 4 4 4 1 PPR repeat MIT PF04212.18 PVD27251.1 - 0.0065 16.5 6.7 2 8.5 0.8 5.3 5 1 0 5 5 4 1 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 PVD27251.1 - 0.015 15.5 0.7 3.9 7.8 0.0 4.1 4 0 0 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 TPR_10 PF13374.6 PVD27251.1 - 0.016 15.1 12.8 0.44 10.5 0.0 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.9 PVD27251.1 - 0.025 14.3 5.2 0.084 12.6 0.3 3.3 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF627 PF04781.12 PVD27251.1 - 0.073 13.1 5.5 1.9 8.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TOM20_plant PF06552.12 PVD27251.1 - 0.075 12.8 3.9 4.5 7.0 0.0 3.8 2 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Exonuc_VII_S PF02609.16 PVD27251.1 - 0.28 11.3 5.2 1.6 8.9 0.2 4.4 6 0 0 6 6 5 0 Exonuclease VII small subunit BTAD PF03704.17 PVD27251.1 - 0.3 11.5 2.6 12 6.3 0.1 3.7 3 1 0 3 3 3 0 Bacterial transcriptional activator domain FAT PF02259.23 PVD27251.1 - 1 8.5 7.1 1.3 8.2 0.2 3.4 2 2 0 3 3 3 0 FAT domain PapG_N PF03627.13 PVD27252.1 - 0.019 14.7 0.0 0.021 14.5 0.0 1.0 1 0 0 1 1 1 0 PapG carbohydrate binding domain DUF3915 PF13054.6 PVD27264.1 - 0.033 14.2 1.2 0.051 13.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) VASt PF16016.5 PVD27267.1 - 2.2e-34 119.1 0.0 4.6e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 PVD27267.1 - 4.1e-27 94.3 0.2 8.3e-27 93.3 0.2 1.5 1 0 0 1 1 1 1 GRAM domain KRAB PF01352.27 PVD27267.1 - 0.16 11.6 1.7 0.43 10.3 1.7 1.7 1 0 0 1 1 1 0 KRAB box Sulfatase PF00884.23 PVD27268.1 - 9.4e-23 81.1 0.4 1.1e-22 80.8 0.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 PVD27268.1 - 0.0083 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 PVD27268.1 - 0.019 15.7 0.0 0.033 14.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase I-set PF07679.16 PVD27269.1 - 1.3e-12 47.6 0.4 0.11 12.5 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin I-set domain V-set PF07686.17 PVD27269.1 - 4.1e-11 43.0 13.3 0.065 13.4 1.1 5.0 4 1 0 4 4 4 4 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD27269.1 - 3.3e-10 40.4 19.0 0.13 12.9 1.1 5.6 4 3 0 4 4 4 4 Immunoglobulin domain DUF2034 PF10356.9 PVD27269.1 - 6.3e-05 22.5 0.0 0.081 12.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Ig_2 PF13895.6 PVD27269.1 - 7.1e-05 23.1 25.8 0.65 10.4 1.9 6.6 2 2 2 4 4 4 4 Immunoglobulin domain ig PF00047.25 PVD27269.1 - 0.001 19.2 13.2 5 7.4 0.2 5.2 4 4 0 4 4 4 3 Immunoglobulin domain DUF5626 PF18540.1 PVD27269.1 - 0.016 15.7 0.3 7.6 7.1 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5626) Izumo-Ig PF16706.5 PVD27269.1 - 0.02 15.0 0.1 11 6.1 0.0 4.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain PSI PF01437.25 PVD27269.1 - 0.02 15.4 0.7 28 5.3 0.0 3.5 3 0 0 3 3 3 0 Plexin repeat ASPRs PF17641.2 PVD27269.1 - 0.039 14.2 1.7 21 5.4 0.0 3.9 4 0 0 4 4 4 0 Ancylostoma-associated secreted protein related Sulfatase PF00884.23 PVD27271.1 - 1.8e-59 201.6 0.2 2.1e-59 201.5 0.2 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD27271.1 - 0.00013 21.7 2.3 0.0029 17.2 2.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD27271.1 - 0.066 12.3 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase PF00884.23 PVD27272.1 - 7e-16 58.5 0.0 3.5e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 PVD27272.1 - 2.1e-07 31.7 0.0 3.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD27272.1 - 0.0055 16.9 0.2 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase PF00884.23 PVD27273.1 - 2.9e-16 59.8 0.0 1.7e-11 44.1 0.0 2.1 1 1 1 2 2 2 2 Sulfatase SRCR PF00530.18 PVD27274.1 - 4.1e-60 200.5 6.0 3e-23 82.2 0.1 3.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD27274.1 - 6.9e-18 65.0 1.8 0.00029 21.3 0.1 3.4 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD27274.1 - 1.5e-08 35.2 0.0 0.025 15.1 0.0 3.3 3 0 0 3 3 3 3 Hepsin, SRCR domain MtmB PF05369.12 PVD27274.1 - 0.0011 17.9 0.0 0.8 8.4 0.0 2.2 2 0 0 2 2 2 2 Monomethylamine methyltransferase MtmB DUF1937 PF09152.10 PVD27274.1 - 0.0013 19.5 0.1 7.2 7.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1937) Viral_RdRp_C PF17501.2 PVD27274.1 - 0.067 13.6 0.3 4.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Viral RNA-directed RNA polymerase Usher_TcfC PF17271.2 PVD27274.1 - 0.87 8.3 2.8 13 4.4 0.5 2.1 2 0 0 2 2 2 0 TcfC Usher-like barrel domain Toxin_4 PF00706.17 PVD27274.1 - 6.4 7.3 8.0 1.2e+02 3.2 0.1 3.9 4 0 0 4 4 4 0 Anenome neurotoxin SRCR PF00530.18 PVD27275.1 - 3.8e-26 91.5 0.1 5.3e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD27275.1 - 2.7e-05 24.6 0.1 6.7e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Peptidase_S10 PF00450.22 PVD27276.1 - 3.3e-130 435.3 0.0 3.8e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 PVD27276.1 - 0.019 14.4 0.0 0.15 11.5 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Ependymin PF00811.18 PVD27277.1 - 4.6e-26 91.5 0.0 3.1e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Ependymin HMG_box_2 PF09011.10 PVD27278.1 - 1.1e-11 45.1 3.0 1.1e-11 45.1 3.0 3.0 2 1 1 3 3 3 1 HMG-box domain HMG_box PF00505.19 PVD27278.1 - 4e-09 36.8 6.5 4e-09 36.8 6.5 3.2 3 1 0 3 3 3 1 HMG (high mobility group) box Endonuc_Holl PF10107.9 PVD27278.1 - 0.0022 17.9 2.4 0.0022 17.9 2.4 1.7 2 0 0 2 2 2 1 Endonuclease related to archaeal Holliday junction resolvase ATLF PF07737.11 PVD27278.1 - 0.014 14.7 0.5 0.014 14.7 0.5 1.7 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain CagY_M PF07337.11 PVD27278.1 - 0.15 11.7 2.7 7.9 6.2 0.2 2.8 2 0 0 2 2 2 0 DC-EC Repeat Ependymin PF00811.18 PVD27280.1 - 1.6e-14 54.2 0.0 3.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 PVD27281.1 - 7.4e-31 107.0 4.0 5.3e-17 62.3 0.1 2.8 2 1 1 3 3 3 2 Ependymin S-l_SbsC_C PF18316.1 PVD27282.1 - 0.035 14.6 0.1 0.098 13.2 0.1 1.7 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Pre-SET PF05033.16 PVD27282.1 - 3.1 8.5 13.1 9.5 6.9 0.2 3.2 2 1 0 3 3 3 0 Pre-SET motif Orn_Arg_deC_N PF02784.16 PVD27283.1 - 2.3e-40 138.5 0.0 9.6e-40 136.5 0.0 1.8 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD27283.1 - 1.3e-15 57.4 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 PVD27284.1 - 3.7e-52 177.2 0.0 4.9e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD27284.1 - 4.9e-15 55.5 0.0 9.5e-15 54.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Complex1_51K PF01512.17 PVD27284.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Orn_DAP_Arg_deC PF00278.22 PVD27285.1 - 1.9e-10 40.8 0.0 2.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 PVD27286.1 - 5.8e-08 32.4 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_Arg_deC_N PF02784.16 PVD27287.1 - 1.1e-39 136.3 0.0 3.1e-39 134.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD27287.1 - 1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 PVD27288.1 - 1.3e-74 250.7 0.0 1.6e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD27288.1 - 6.9e-16 58.3 0.0 8.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 PVD27289.1 - 3.4e-53 180.6 0.0 4.6e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PVD27289.1 - 8.2e-14 51.6 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CxC6 PF18721.1 PVD27290.1 - 0.064 13.5 1.0 0.23 11.8 0.1 2.5 3 0 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases EIF_2_alpha PF07541.12 PVD27291.1 - 0.023 14.8 0.2 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit DUF4010 PF13194.6 PVD27291.1 - 0.057 13.1 0.2 0.083 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) C2-set_2 PF08205.12 PVD27292.1 - 0.00012 22.0 2.2 0.0089 16.1 0.1 2.8 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27292.1 - 0.0035 17.9 0.2 0.016 15.8 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Pkinase_Tyr PF07714.17 PVD27293.1 - 7.3e-25 87.7 0.7 2.2e-24 86.1 0.6 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD27293.1 - 1.1e-20 74.1 0.5 5.1e-20 71.9 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PVD27293.1 - 0.03 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HisG_C PF08029.11 PVD27293.1 - 0.049 13.8 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 HisG, C-terminal domain Retro_M PF02813.14 PVD27293.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral M domain Pkinase_Tyr PF07714.17 PVD27294.1 - 3.2e-43 147.9 0.1 4.5e-30 104.8 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD27294.1 - 8e-29 100.8 1.2 2.1e-22 79.7 0.1 3.2 2 1 1 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 PVD27294.1 - 0.00013 21.4 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 PVD27295.1 - 4.9e-40 137.4 0.3 2.4e-32 112.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD27295.1 - 2e-30 106.0 1.4 1.2e-26 93.7 0.4 2.5 2 0 0 2 2 2 2 Protein kinase domain KH_1 PF00013.29 PVD27295.1 - 0.0001 22.0 0.2 0.00023 20.9 0.2 1.6 1 0 0 1 1 1 1 KH domain DUF4448 PF14610.6 PVD27295.1 - 0.014 15.2 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3377 PF11857.8 PVD27295.1 - 0.11 12.5 0.5 0.29 11.1 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 PVD27295.1 - 0.32 11.1 1.6 0.74 9.9 1.6 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CBM_X2 PF03442.14 PVD27296.1 - 0.11 12.6 0.0 0.62 10.2 0.0 2.0 1 1 1 2 2 2 0 Carbohydrate binding domain X2 Phage_Coat_Gp8 PF05371.12 PVD27298.1 - 0.19 11.5 0.5 0.35 10.7 0.5 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 DUF4366 PF14283.6 PVD27298.1 - 0.33 11.0 2.0 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Plk4_PB2 PF18409.1 PVD27299.1 - 0.013 16.1 1.5 0.22 12.2 0.0 2.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Pkinase_Tyr PF07714.17 PVD27300.1 - 5.4e-14 52.1 0.0 9.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SCAN PF02023.17 PVD27300.1 - 3.2e-13 49.3 0.5 7e-13 48.2 0.5 1.6 1 0 0 1 1 1 1 SCAN domain Peptidase_C33 PF05412.12 PVD27300.1 - 0.018 15.1 0.0 0.068 13.2 0.0 2.0 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Pkinase PF00069.25 PVD27300.1 - 0.041 13.3 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein kinase domain CHAT PF12770.7 PVD27300.1 - 0.12 11.8 0.9 0.21 11.0 0.9 1.4 1 0 0 1 1 1 0 CHAT domain RVP PF00077.20 PVD27300.1 - 0.14 12.5 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease KH_1 PF00013.29 PVD27300.1 - 0.15 11.9 0.1 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 KH domain Asp_protease_2 PF13650.6 PVD27300.1 - 0.17 12.6 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease EVC2_like PF12297.8 PVD27302.1 - 0.011 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CENP-S PF15630.6 PVD27304.1 - 0.031 14.7 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 CENP-S protein Calici_MSP PF05752.11 PVD27304.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein fn3 PF00041.21 PVD27305.1 - 9.6e-20 70.7 0.2 6.2e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 PVD27305.1 - 8.2e-06 26.0 0.1 2.4e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 PVD27305.1 - 3.1e-05 24.0 0.1 7.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27305.1 - 0.00026 21.0 0.1 0.0007 19.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27305.1 - 0.0027 18.3 0.1 0.01 16.4 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27305.1 - 0.034 14.5 0.1 0.091 13.1 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD27305.1 - 0.11 12.7 1.4 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 RVT_1 PF00078.27 PVD27306.1 - 4.8e-27 94.9 0.1 7.2e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FRG PF08867.11 PVD27306.1 - 0.092 13.7 0.0 0.2 12.6 0.0 1.7 1 0 0 1 1 1 0 FRG domain 7tm_1 PF00001.21 PVD27307.1 - 0.041 13.2 1.3 4.4 6.6 0.0 2.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD27307.1 - 0.3 10.7 3.1 6 6.4 0.1 2.4 2 0 0 2 2 2 0 Srg family chemoreceptor SID-1_RNA_chan PF13965.6 PVD27308.1 - 6.4e-56 190.0 10.9 2.6e-28 98.8 1.9 3.1 1 1 2 3 3 3 3 dsRNA-gated channel SID-1 Claudin_2 PF13903.6 PVD27308.1 - 0.004 16.9 0.1 0.0064 16.3 0.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3149 PF11346.8 PVD27308.1 - 0.0061 16.1 0.2 0.019 14.6 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) DUF3852 PF12963.7 PVD27308.1 - 0.007 16.7 2.1 0.055 13.8 1.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3852) DUF2976 PF11190.8 PVD27308.1 - 0.024 14.4 1.3 0.06 13.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) IgGFc_binding PF17517.2 PVD27308.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 IgGFc binding protein DUF2207 PF09972.9 PVD27308.1 - 0.033 13.0 0.7 0.052 12.3 0.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DctQ PF04290.12 PVD27308.1 - 0.096 12.6 3.5 0.21 11.5 3.5 1.5 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component ABC_trans_CmpB PF06541.11 PVD27308.1 - 0.62 10.3 6.2 0.85 9.8 5.5 1.6 1 1 0 1 1 1 0 Putative ABC-transporter type IV Ceramidase PF05875.12 PVD27308.1 - 4.6 6.6 9.1 0.071 12.5 1.2 2.0 2 1 0 2 2 2 0 Ceramidase ECSCR PF15820.5 PVD27310.1 - 0.015 15.1 0.5 0.037 13.8 0.5 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator UPF0184 PF03670.13 PVD27310.1 - 0.057 13.8 2.4 0.1 13.0 0.3 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Orf78 PF06024.12 PVD27310.1 - 0.088 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Protocadherin PF08374.11 PVD27310.1 - 0.3 11.0 1.1 0.46 10.4 1.1 1.2 1 0 0 1 1 1 0 Protocadherin Pre-SET PF05033.16 PVD27311.1 - 0.0041 17.8 1.4 0.65 10.7 0.2 2.6 3 0 0 3 3 3 1 Pre-SET motif CD34_antigen PF06365.12 PVD27311.1 - 0.066 12.8 0.0 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family FA_hydroxylase PF04116.13 PVD27311.1 - 0.069 13.5 0.9 0.53 10.6 0.5 2.3 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily RL11D PF11088.8 PVD27311.1 - 0.16 12.3 2.6 0.45 10.8 0.0 2.7 2 2 1 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 RIFIN PF02009.16 PVD27311.1 - 0.21 11.4 0.7 0.25 11.2 0.1 1.5 2 0 0 2 2 2 0 Rifin Stevor PF17410.2 PVD27311.1 - 0.29 10.7 1.9 0.49 9.9 1.9 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ECSCR PF15820.5 PVD27311.1 - 1.8 8.5 6.0 0.13 12.1 0.7 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FeoB_C PF07664.12 PVD27311.1 - 7.6 6.3 7.4 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus CD34_antigen PF06365.12 PVD27317.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family GPHR_N PF12537.8 PVD27318.1 - 3.4e-28 97.5 0.2 8.4e-28 96.3 0.1 1.8 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal ABA_GPCR PF12430.8 PVD27318.1 - 2.6e-22 79.5 4.8 2.6e-22 79.5 4.8 2.1 3 1 0 3 3 3 1 Abscisic acid G-protein coupled receptor K-box PF01486.17 PVD27318.1 - 0.077 13.2 1.7 9.5 6.5 0.2 2.2 2 0 0 2 2 2 0 K-box region Gemini_mov PF01708.16 PVD27318.1 - 0.16 11.8 1.7 0.57 10.0 1.7 2.0 1 0 0 1 1 1 0 Geminivirus putative movement protein UCH PF00443.29 PVD27319.1 - 3.7e-47 161.0 0.2 6.5e-47 160.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD27319.1 - 4.4e-07 29.8 3.0 2e-05 24.4 3.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ig_2 PF13895.6 PVD27320.1 - 0.079 13.3 2.1 0.93 9.9 0.4 2.3 2 1 0 2 2 2 0 Immunoglobulin domain TPR_2 PF07719.17 PVD27322.1 - 1.7e-05 24.6 5.7 0.19 12.0 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 PVD27322.1 - 0.0043 17.4 1.1 0.012 15.9 1.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD27322.1 - 0.0083 16.4 0.3 0.021 15.1 0.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_19 PF14559.6 PVD27322.1 - 0.018 15.5 0.8 1.5 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD27322.1 - 0.022 14.6 1.3 4.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD27322.1 - 0.022 14.8 0.0 0.081 12.9 0.0 2.0 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 PVD27322.1 - 0.25 11.6 4.2 2.5 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD27322.1 - 1.2 9.6 3.8 47 4.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPH PF13868.6 PVD27323.1 - 4.4e-86 288.6 142.0 4.4e-86 288.6 142.0 2.2 2 0 0 2 2 2 2 Trichohyalin-plectin-homology domain GA-like PF17573.2 PVD27323.1 - 0.017 15.0 1.6 0.25 11.3 0.1 3.3 2 0 0 2 2 2 0 GA-like domain tRNA_SAD PF07973.14 PVD27324.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 PVD27324.1 - 0.00018 21.4 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain HLH PF00010.26 PVD27325.1 - 5.1e-18 64.8 0.2 9.3e-18 63.9 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rootletin PF15035.6 PVD27325.1 - 0.0031 17.5 2.7 0.0051 16.8 2.7 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 PVD27325.1 - 0.02 14.3 1.4 0.031 13.6 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 PVD27325.1 - 0.079 13.2 4.4 0.14 12.5 4.4 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 FlaC_arch PF05377.11 PVD27325.1 - 0.11 12.8 1.3 0.63 10.5 0.4 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Latarcin PF10279.9 PVD27325.1 - 0.27 11.7 1.8 0.44 11.0 1.8 1.4 1 0 0 1 1 1 0 Latarcin precursor MCC-bdg_PDZ PF10506.9 PVD27325.1 - 0.4 10.7 3.5 9.3 6.4 3.5 2.5 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cep57_CLD_2 PF14197.6 PVD27325.1 - 2.8 8.1 8.0 19 5.4 2.9 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 HSP70 PF00012.20 PVD27326.1 - 5.7e-69 232.9 80.3 1.4e-66 225.0 33.5 4.7 2 1 2 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.13 PVD27326.1 - 0.0013 17.6 0.7 0.052 12.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Calponin PF00402.18 PVD27327.1 - 1.7e-94 308.9 58.4 8.9e-14 50.8 2.2 7.5 7 0 0 7 7 7 7 Calponin family repeat CH PF00307.31 PVD27327.1 - 3.7e-18 65.7 0.0 5.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain PNP_UDP_1 PF01048.20 PVD27327.1 - 0.00052 19.3 6.0 8.9 5.5 0.0 5.2 2 2 3 5 5 5 1 Phosphorylase superfamily Beta-APP PF03494.13 PVD27327.1 - 0.72 9.7 23.0 46 4.0 0.2 7.7 7 1 0 7 7 7 0 Beta-amyloid peptide (beta-APP) Nup_retrotrp_bd PF10599.9 PVD27327.1 - 2.6 8.7 8.4 84 3.9 0.9 3.8 1 1 1 2 2 2 0 Retro-transposon transporting motif Thiamine_BP PF01910.17 PVD27327.1 - 3.2 7.7 4.0 26 4.8 0.0 4.1 6 0 0 6 6 6 0 Thiamine-binding protein Scramblase PF03803.15 PVD27329.1 - 7.8e-37 126.7 0.0 9.5e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Scramblase 7TM_GPCR_Srw PF10324.9 PVD27330.1 - 5.1e-17 62.1 12.0 6.1e-17 61.9 12.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD27330.1 - 1.8e-09 37.3 10.1 2.4e-09 36.9 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EVC2_like PF12297.8 PVD27330.1 - 0.005 15.6 0.2 0.0067 15.2 0.2 1.2 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein DUF4231 PF14015.6 PVD27330.1 - 0.076 13.5 0.4 0.21 12.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Gaa1 PF04114.14 PVD27330.1 - 0.29 10.1 6.7 0.34 9.9 6.7 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component 30K_MP_C_Ter PF11330.8 PVD27335.1 - 0.081 12.2 0.2 0.087 12.1 0.2 1.1 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins TraB PF01963.17 PVD27336.1 - 0.072 13.0 1.8 0.14 12.1 1.8 1.8 1 1 0 1 1 1 0 TraB family Ig_3 PF13927.6 PVD27337.1 - 1.7e-98 323.3 16.5 6.5e-16 58.7 0.0 9.9 10 0 0 10 10 9 9 Immunoglobulin domain I-set PF07679.16 PVD27337.1 - 1.1e-94 310.7 0.1 8.9e-17 61.0 0.0 10.6 10 1 0 10 10 10 9 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27337.1 - 3e-68 226.1 14.6 6.5e-12 45.6 0.0 9.9 9 1 0 9 9 9 9 Immunoglobulin domain ig PF00047.25 PVD27337.1 - 9.7e-61 202.0 13.1 7.1e-10 38.9 0.0 10.4 9 1 0 9 9 9 8 Immunoglobulin domain V-set PF07686.17 PVD27337.1 - 3e-25 88.5 23.6 0.0016 18.5 0.1 12.4 8 5 4 12 12 12 5 Immunoglobulin V-set domain fn3 PF00041.21 PVD27337.1 - 1.2e-14 54.4 0.3 2e-06 28.1 0.3 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_6 PF18452.1 PVD27337.1 - 4.7e-14 51.7 3.4 0.087 12.4 0.0 8.2 8 0 0 8 8 8 4 Immunoglobulin domain Ig_4 PF16680.5 PVD27337.1 - 3.4e-11 43.2 0.0 0.081 13.2 0.0 6.5 6 0 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD27337.1 - 4.6e-10 39.4 0.2 0.064 13.3 0.0 6.6 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD27337.1 - 6.1e-10 39.4 0.0 0.58 10.6 0.0 6.8 8 0 0 8 8 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD27337.1 - 2.4e-08 33.9 0.1 6.1 7.0 0.0 7.0 8 0 0 8 8 7 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD27337.1 - 0.0031 17.6 0.3 2.2 8.5 0.0 4.2 5 0 0 5 5 4 1 Immunoglobulin C2-set domain Ig_C17orf99 PF17736.1 PVD27337.1 - 0.0075 16.3 5.3 2.1 8.4 0.0 6.3 7 2 0 7 7 7 1 C17orf99 Ig domain Y_Y_Y PF07495.13 PVD27337.1 - 0.019 14.9 0.0 0.36 10.8 0.0 2.8 2 0 0 2 2 2 0 Y_Y_Y domain Big_3_5 PF16640.5 PVD27337.1 - 0.054 13.7 1.2 18 5.6 0.1 4.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) C1-set PF07654.15 PVD27337.1 - 0.062 13.7 1.8 36 4.8 0.0 4.8 5 0 0 5 5 4 0 Immunoglobulin C1-set domain PCSK9_C1 PF18459.1 PVD27337.1 - 0.88 9.8 4.9 6.8 6.9 0.0 4.4 6 0 0 6 6 4 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain zf-H2C2_2 PF13465.6 PVD27338.1 - 3.7e-59 194.7 93.5 7.9e-08 32.4 0.1 12.5 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.26 PVD27338.1 - 1.5e-38 129.1 107.6 9.1e-06 25.8 0.2 12.3 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27338.1 - 8e-29 97.8 98.8 8.8e-05 23.0 0.1 12.0 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD27338.1 - 7.8e-13 48.1 81.2 0.02 14.9 1.1 12.6 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD27338.1 - 3.2e-06 27.3 64.6 0.2 12.0 1.4 10.2 9 2 1 10 10 10 6 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 PVD27338.1 - 5.9e-06 26.9 39.0 0.17 12.7 0.1 6.9 3 1 3 6 6 6 3 zinc-ribbon family zf-H2C2_5 PF13909.6 PVD27338.1 - 0.00018 21.2 5.5 0.0022 17.7 0.6 11.5 11 2 0 11 11 11 5 C2H2-type zinc-finger domain zf-met PF12874.7 PVD27338.1 - 0.0041 17.5 77.8 0.032 14.6 1.9 10.9 11 0 0 11 11 10 5 Zinc-finger of C2H2 type DUF3268 PF11672.8 PVD27338.1 - 0.013 15.9 31.1 0.22 11.8 1.9 5.6 3 2 3 6 6 6 0 zinc-finger-containing domain GAGA PF09237.11 PVD27338.1 - 0.02 14.7 14.7 9.9 6.1 0.0 6.5 3 1 4 7 7 7 0 GAGA factor zf-C2HE PF16278.5 PVD27338.1 - 0.022 15.2 0.5 0.022 15.2 0.5 9.1 7 3 4 11 11 9 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 PVD27338.1 - 0.023 14.4 0.1 0.054 13.3 0.3 9.2 11 0 0 11 11 11 0 zinc-finger C2H2-type HTH_18 PF12833.7 PVD27338.1 - 0.63 10.3 6.5 16 5.8 0.1 4.7 5 2 0 5 5 4 0 Helix-turn-helix domain COX5B PF01215.19 PVD27338.1 - 1.9 8.2 6.4 7.3 6.3 0.3 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Vb BTB PF00651.31 PVD27339.1 - 1.5e-23 83.1 2.0 2.9e-23 82.2 0.2 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27339.1 - 6e-16 57.8 8.8 0.0027 17.2 0.0 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 PVD27339.1 - 1.7e-12 47.2 1.9 0.073 13.4 0.0 6.1 4 2 2 6 6 6 3 Kelch motif BACK PF07707.15 PVD27339.1 - 8.4e-12 45.1 4.3 8.4e-12 45.1 4.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 PVD27339.1 - 5e-11 42.3 0.3 0.021 14.8 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PVD27339.1 - 3.9e-10 39.6 0.1 0.4 10.7 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD27339.1 - 2.3e-08 33.7 0.2 0.003 17.5 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 PVD27339.1 - 0.02 15.2 0.6 11 6.4 0.0 3.7 4 1 0 4 4 4 0 Galactose oxidase, central domain SID-1_RNA_chan PF13965.6 PVD27340.1 - 4.4e-155 517.5 22.5 1.9e-106 356.9 3.9 4.1 2 1 2 4 4 4 4 dsRNA-gated channel SID-1 BTB PF00651.31 PVD27341.1 - 4.2e-19 68.8 0.0 7.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27341.1 - 9.1e-19 66.8 4.7 1.5e-05 24.4 0.0 7.2 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.6 PVD27341.1 - 3.1e-13 49.5 0.3 0.029 14.4 0.0 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD27341.1 - 1.2e-12 47.3 5.1 0.0063 16.4 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PVD27341.1 - 1.5e-11 44.1 3.0 0.18 12.1 0.1 5.7 4 2 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PVD27341.1 - 1.5e-07 31.2 3.9 0.053 13.5 0.0 5.1 4 1 1 5 5 5 2 Kelch motif BACK PF07707.15 PVD27341.1 - 0.00013 22.0 1.1 0.00037 20.6 0.6 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD27341.1 - 0.00022 21.4 0.8 10 6.5 0.0 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain BTB PF00651.31 PVD27342.1 - 1.7e-23 82.9 0.5 5.4e-23 81.3 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27342.1 - 1.7e-21 75.5 8.9 9.9e-07 28.2 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD27342.1 - 2.7e-14 52.8 0.9 0.007 16.6 0.0 4.8 4 0 0 4 4 4 4 Kelch motif BACK PF07707.15 PVD27342.1 - 2e-11 43.9 1.6 9e-11 41.8 0.5 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 PVD27342.1 - 2.9e-11 42.9 2.4 0.22 11.5 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PVD27342.1 - 5.3e-09 35.9 0.3 1.3 9.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PVD27342.1 - 0.0032 17.5 3.9 1.6 8.8 0.1 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF3342 PF11822.8 PVD27342.1 - 0.0071 16.5 0.3 0.014 15.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_3 PF13415.6 PVD27342.1 - 0.0083 16.4 1.6 15 6.0 0.1 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain CoA_trans PF01144.23 PVD27342.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase BTB PF00651.31 PVD27343.1 - 1.3e-21 76.9 0.0 2.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD27343.1 - 2.8e-13 49.9 2.7 3.5e-13 49.5 1.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD27343.1 - 2.4e-12 46.2 8.5 0.023 14.3 0.3 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PVD27343.1 - 1.5e-11 44.1 2.2 0.014 15.7 0.0 5.1 4 1 2 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD27343.1 - 2.8e-11 42.9 0.7 0.0059 16.5 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PVD27343.1 - 9.2e-11 41.6 1.7 0.74 9.9 0.0 6.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD27343.1 - 4.1e-10 39.4 1.1 0.011 15.7 0.0 4.0 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PVD27343.1 - 0.0012 19.1 1.3 4.9 7.6 0.1 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain BTB PF00651.31 PVD27344.1 - 1.6e-21 76.6 0.0 4.3e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 PVD27344.1 - 6.4e-15 54.8 0.8 0.011 16.0 0.0 5.7 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PVD27344.1 - 3.9e-14 52.0 5.9 0.023 14.3 0.0 7.1 6 1 0 6 6 6 4 Kelch motif BACK PF07707.15 PVD27344.1 - 1.8e-13 50.5 1.4 5.3e-13 49.0 1.4 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD27344.1 - 2.9e-13 49.6 0.4 0.12 12.4 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD27344.1 - 1.4e-11 43.9 0.1 0.0015 18.4 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PVD27344.1 - 1.6e-11 43.9 0.8 0.0016 18.4 0.0 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PVD27344.1 - 5.3e-05 23.4 1.2 4.5 7.7 0.0 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Patched PF02460.18 PVD27345.1 - 1.2e-110 371.0 22.4 1.6e-110 370.5 22.4 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD27345.1 - 1.4e-30 106.1 8.9 1.4e-30 106.1 8.9 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation BTB PF00651.31 PVD27345.1 - 5.8e-16 58.7 0.1 1.9e-15 57.1 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27345.1 - 1.3e-15 56.6 2.4 1.6e-08 34.0 0.0 4.5 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 PVD27345.1 - 7.8e-14 51.0 0.1 0.0025 17.7 0.0 4.2 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 PVD27345.1 - 1.7e-12 47.1 2.4 4.9e-05 23.5 0.1 3.9 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 PVD27345.1 - 3.7e-10 39.6 0.1 0.0015 18.4 0.0 4.0 2 1 1 3 3 3 3 Kelch motif BACK PF07707.15 PVD27345.1 - 4.1e-10 39.7 2.1 6e-10 39.1 0.3 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD27345.1 - 0.00015 22.0 0.3 1.4 9.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain ACR_tran PF00873.19 PVD27345.1 - 0.23 9.0 18.6 0.47 8.1 18.6 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.15 PVD27345.1 - 2.4 7.0 30.9 2.4 7.0 6.4 2.2 2 0 0 2 2 2 0 MMPL family ketoacyl-synt PF00109.26 PVD27347.1 - 2e-50 171.7 7.0 4.8e-35 121.3 4.6 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 PVD27347.1 - 1.1e-45 156.5 0.0 1.8e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 PVD27347.1 - 2.8e-22 79.3 0.0 6.4e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 PVD27347.1 - 2e-17 63.3 0.0 4.3e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 PVD27347.1 - 1.2e-13 51.4 0.4 3.7e-13 49.9 0.1 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 PVD27347.1 - 1.5e-06 27.8 0.5 2.7e-06 26.9 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 PVD27348.1 - 9.5e-24 84.3 0.1 2.9e-11 43.6 0.0 2.6 1 1 1 2 2 2 2 KR domain PP-binding PF00550.25 PVD27348.1 - 3.6e-06 27.2 0.2 9.9e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD27348.1 - 4e-05 23.2 0.0 8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD27348.1 - 0.063 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF4898 PF16239.5 PVD27348.1 - 0.13 12.3 0.8 0.4 10.6 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) BTB PF00651.31 PVD27349.1 - 3.4e-23 82.0 0.0 8e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27349.1 - 1.5e-17 62.9 3.4 0.012 15.1 0.0 7.3 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 PVD27349.1 - 1.1e-15 57.4 0.1 3.2e-05 23.8 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD27349.1 - 1.8e-15 56.6 1.6 0.0036 17.5 0.0 5.9 4 2 2 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD27349.1 - 1.1e-13 50.5 1.5 0.0094 15.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 PVD27349.1 - 4.3e-12 46.0 0.9 4.3e-12 46.0 0.9 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 PVD27349.1 - 6.7e-10 38.7 3.1 0.098 12.7 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PVD27349.1 - 1.4e-05 25.2 2.7 0.25 11.7 0.0 5.7 5 1 0 5 5 5 1 Galactose oxidase, central domain BTB PF00651.31 PVD27350.1 - 9.5e-22 77.3 0.1 2.5e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 PVD27350.1 - 2.7e-17 62.4 4.2 4.8e-05 23.5 0.0 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 PVD27350.1 - 3.6e-16 58.5 14.6 0.0002 20.9 0.0 6.3 6 1 0 6 6 6 4 Kelch motif BACK PF07707.15 PVD27350.1 - 2.1e-14 53.5 3.2 2.1e-14 53.5 3.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 PVD27350.1 - 1.1e-11 44.2 8.3 0.0043 17.0 0.1 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PVD27350.1 - 2.9e-11 43.1 8.8 0.0066 16.4 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PVD27350.1 - 3.9e-08 33.2 7.4 0.65 10.1 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Pigment_DH PF06324.11 PVD27350.1 - 0.23 11.6 0.9 0.86 9.8 0.9 2.0 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Kelch_3 PF13415.6 PVD27350.1 - 0.5 10.7 4.9 37 4.8 0.0 4.6 6 0 0 6 6 6 0 Galactose oxidase, central domain BTB PF00651.31 PVD27351.1 - 2.3e-24 85.7 0.0 5e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27351.1 - 8e-21 73.4 1.4 4.7e-06 26.1 0.0 7.4 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 PVD27351.1 - 4.1e-19 68.3 0.5 7.3e-05 22.7 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD27351.1 - 2.4e-17 62.5 1.2 1.8e-05 24.9 0.0 6.1 4 2 2 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD27351.1 - 1.1e-15 56.9 0.8 0.0034 17.3 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PVD27351.1 - 2.5e-12 46.5 0.8 0.0029 17.6 0.0 5.4 4 1 1 5 5 5 2 Kelch motif BACK PF07707.15 PVD27351.1 - 2.4e-11 43.6 3.2 2.4e-11 43.6 3.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD27351.1 - 1.6e-07 31.4 2.4 0.68 10.3 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain DUF3342 PF11822.8 PVD27351.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) BTB PF00651.31 PVD27352.1 - 1.9e-22 79.6 0.0 3.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 PVD27352.1 - 1.9e-14 52.9 9.9 0.018 14.6 0.1 7.2 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 PVD27352.1 - 4e-14 51.9 1.6 0.00014 21.7 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PVD27352.1 - 2.4e-13 49.8 0.2 0.04 14.2 0.0 5.6 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD27352.1 - 2.7e-13 49.7 1.8 0.073 13.1 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD27352.1 - 7.3e-13 48.2 0.6 0.0028 17.6 0.1 5.4 4 1 1 5 5 5 4 Kelch motif BACK PF07707.15 PVD27352.1 - 7e-10 38.9 4.1 1.4e-09 37.9 4.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD27352.1 - 0.00015 21.9 3.5 0.14 12.5 0.0 5.1 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD27353.1 - 1.2e-10 40.8 3.8 5.3e-05 22.7 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD27353.1 - 6.1e-06 26.1 0.0 0.056 13.5 0.0 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD27353.1 - 2.2e-05 24.3 0.5 0.083 12.9 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 PVD27353.1 - 3e-05 23.8 0.5 0.17 11.9 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 PVD27353.1 - 9.8e-05 22.5 2.5 0.23 11.8 0.2 3.1 2 2 1 3 3 3 2 Kelch motif BTB PF00651.31 PVD27354.1 - 4.8e-16 59.0 0.1 1e-15 57.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 PVD27354.1 - 2.1e-13 50.0 0.5 2.4e-07 30.8 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 PVD27354.1 - 2.9e-12 45.9 1.7 0.00014 21.4 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 PVD27354.1 - 1.2e-09 38.0 0.0 0.0091 16.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 PVD27354.1 - 2.3e-09 36.8 0.3 0.093 12.7 0.0 3.6 3 0 0 3 3 3 3 Kelch motif BACK PF07707.15 PVD27354.1 - 3.3e-06 27.2 0.1 6.5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD27354.1 - 9e-06 25.6 0.0 0.019 15.0 0.0 3.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD27354.1 - 0.00032 20.9 0.2 2.2 8.7 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD27355.1 - 1.7e-18 66.2 0.8 0.0025 18.1 0.1 5.4 3 2 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 PVD27355.1 - 3.1e-15 55.5 0.5 0.003 17.1 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 PVD27355.1 - 1.2e-11 44.3 0.3 0.014 15.4 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PVD27355.1 - 2e-11 43.4 0.7 0.0012 18.7 0.0 4.7 5 0 0 5 5 5 3 Kelch motif BACK PF07707.15 PVD27355.1 - 1.3e-09 38.0 2.9 1.3e-09 38.0 2.9 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD27355.1 - 1.7e-09 37.6 0.1 0.31 11.1 0.1 4.9 4 2 0 4 4 4 3 Galactose oxidase, central domain BTB PF00651.31 PVD27355.1 - 3.2e-09 37.0 0.2 7.6e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 PVD27355.1 - 9.6e-05 22.6 0.3 29 5.1 0.0 4.8 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD27356.1 - 4.7e-16 58.1 7.8 5.7e-07 29.0 0.1 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 PVD27356.1 - 7.2e-15 54.7 1.4 1e-06 28.8 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 PVD27356.1 - 5.8e-11 41.9 0.8 0.0022 17.9 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 PVD27356.1 - 8.5e-08 32.0 0.0 0.016 15.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD27356.1 - 8.1e-05 22.6 2.8 2.9 8.0 0.0 4.5 3 2 0 3 3 3 2 Galactose oxidase, central domain Cerato-platanin PF07249.12 PVD27356.1 - 0.045 13.9 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Cerato-platanin Kelch_3 PF13415.6 PVD27356.1 - 0.045 14.0 0.1 18 5.7 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain C1-set PF07654.15 PVD27357.1 - 0.0034 17.7 0.0 0.008 16.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 PVD27357.1 - 0.0063 16.6 0.1 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27357.1 - 0.069 13.7 0.0 0.39 11.3 0.0 2.2 1 1 1 2 2 2 0 Immunoglobulin domain DUF3246 PF11596.8 PVD27357.1 - 0.69 9.3 13.8 0.47 9.9 7.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Glyco_transf_92 PF01697.27 PVD27358.1 - 3e-21 76.3 0.0 4.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD27358.1 - 0.039 14.5 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PVD27359.1 - 2.4e-52 178.2 0.0 4e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD27359.1 - 4.1e-08 33.6 0.0 0.1 13.1 0.0 3.8 3 0 0 3 3 3 3 Glycosyl transferase family 2 DND1_DSRM PF14709.7 PVD27359.1 - 0.00051 20.2 0.0 12 6.2 0.0 3.4 3 0 0 3 3 3 1 double strand RNA binding domain from DEAD END PROTEIN 1 YoeB_toxin PF06769.14 PVD27359.1 - 0.001 19.0 0.0 19 5.4 0.0 3.5 3 0 0 3 3 3 2 YoeB-like toxin of bacterial type II toxin-antitoxin system DUF302 PF03625.14 PVD27359.1 - 0.0019 18.1 0.0 19 5.3 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function DUF302 RAG2_PHD PF13341.6 PVD27359.1 - 0.0023 18.0 0.5 26 4.9 0.0 3.4 3 0 0 3 3 3 0 RAG2 PHD domain Crp PF00325.20 PVD27359.1 - 0.0026 17.3 0.0 14 5.4 0.0 3.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, crp family Ig_3 PF13927.6 PVD27360.1 - 0.00011 22.8 0.2 0.0025 18.4 0.0 2.7 2 2 1 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27360.1 - 0.00019 21.7 0.3 0.0061 16.9 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD27360.1 - 0.00023 21.3 0.0 0.00065 19.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27360.1 - 0.00082 19.4 0.1 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 C17orf99 Ig domain C2-set_2 PF08205.12 PVD27360.1 - 0.0094 16.0 0.1 7 6.8 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ChitinaseA_N PF08329.10 PVD27360.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain DDE_1 PF03184.19 PVD27361.1 - 4.8e-21 75.2 0.3 4.1e-16 59.1 0.1 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PVD27361.1 - 1.7e-08 34.4 0.0 5.3e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 PVD27361.1 - 6e-06 25.8 0.9 1.2e-05 24.8 0.9 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 PVD27361.1 - 0.0015 18.2 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 PVD27361.1 - 0.01 15.9 0.8 0.019 15.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 PVD27361.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.6 PVD27361.1 - 0.028 14.2 0.2 0.14 11.9 0.1 2.2 2 1 1 3 3 3 0 DDE superfamily endonuclease MarR PF01047.22 PVD27361.1 - 0.04 13.9 0.3 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 PVD27361.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2161 PF09929.9 PVD27361.1 - 0.082 13.0 0.8 8.9 6.5 0.4 2.5 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Sigma70_r4 PF04545.16 PVD27361.1 - 0.087 12.4 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 PVD27361.1 - 0.094 13.2 2.5 0.37 11.3 0.4 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain O-antigen_lig PF13425.6 PVD27361.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein zf-CCHC PF00098.23 PVD27362.1 - 1.9e-07 30.8 4.1 1.9e-07 30.8 4.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 PVD27362.1 - 0.01 15.7 0.6 0.029 14.2 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_4 PF13717.6 PVD27362.1 - 0.047 13.6 0.2 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain RVP PF00077.20 PVD27362.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zinc-ribbons_6 PF07191.12 PVD27362.1 - 0.073 13.1 0.8 4.5 7.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-CCHC_2 PF13696.6 PVD27362.1 - 0.55 10.1 5.0 0.97 9.3 5.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 PVD27363.1 - 1.6e-23 83.4 0.0 3.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1891 PF09004.10 PVD27363.1 - 2.9e-07 30.0 1.8 5.1e-07 29.2 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) KH_1 PF00013.29 PVD27363.1 - 9.9e-05 22.1 0.0 0.00055 19.7 0.0 2.2 2 0 0 2 2 2 1 KH domain Myosin_tail_1 PF01576.19 PVD27364.1 - 1.5e-43 148.9 33.2 2.4e-30 105.2 19.7 2.0 1 1 1 2 2 2 2 Myosin tail Sec8_exocyst PF04048.14 PVD27364.1 - 0.0033 17.3 0.6 0.0033 17.3 0.6 1.8 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF724 PF05266.14 PVD27364.1 - 2.4 7.9 22.7 2.9 7.7 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YAF2_RYBP PF17219.3 PVD27365.1 - 0.00021 20.8 0.3 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 Yaf2/RYBP C-terminal binding motif AAA_19 PF13245.6 PVD27365.1 - 0.0017 18.7 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PVD27365.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 PVD27365.1 - 0.032 14.6 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 PVD27365.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PVD27365.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD27365.1 - 0.098 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF3377 PF11857.8 PVD27366.1 - 0.053 13.4 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4448 PF14610.6 PVD27366.1 - 0.06 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3827 PF12877.7 PVD27366.1 - 0.064 11.6 0.2 0.08 11.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PMP1_2 PF08114.11 PVD27366.1 - 0.35 10.7 1.3 1.2 8.9 1.6 1.8 2 0 0 2 2 2 0 ATPase proteolipid family Gelsolin PF00626.22 PVD27367.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Transposase_22 PF02994.14 PVD27368.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 L1 transposable element RBD-like domain IFT57 PF10498.9 PVD27368.1 - 0.0013 17.8 0.4 0.0021 17.1 0.4 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 FliD_N PF02465.18 PVD27368.1 - 0.0067 17.1 1.0 0.015 16.0 0.6 1.7 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.9 PVD27368.1 - 0.0076 16.3 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HBS1_N PF08938.10 PVD27368.1 - 0.0096 16.2 0.4 4.6 7.6 0.0 2.4 2 0 0 2 2 2 2 HBS1 N-terminus Filament PF00038.21 PVD27368.1 - 0.015 14.9 0.4 0.024 14.2 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF5550 PF17704.1 PVD27368.1 - 0.032 14.4 1.2 0.32 11.1 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5550) Spc7 PF08317.11 PVD27368.1 - 0.047 12.6 0.2 0.074 11.9 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 PVD27368.1 - 0.047 13.0 0.1 0.087 12.2 0.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 PVD27368.1 - 0.059 13.4 1.7 0.19 11.8 0.8 2.4 2 1 0 2 2 2 0 TolA binding protein trimerisation WXG100 PF06013.12 PVD27368.1 - 0.11 12.7 1.8 0.36 11.1 0.4 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Exo_endo_phos PF03372.23 PVD27369.1 - 1.8e-06 27.7 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD27369.1 - 0.034 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD27370.1 - 7.7e-16 58.3 0.3 1.8e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) IFN-gamma PF00714.17 PVD27370.1 - 0.075 12.9 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Interferon gamma MLVIN_C PF18697.1 PVD27371.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Folliculin PF11704.8 PVD27371.1 - 0.87 9.4 4.7 1.4 8.8 4.7 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Flot PF15975.5 PVD27371.1 - 1.4 9.1 18.7 5 7.3 18.7 1.9 1 1 0 1 1 1 0 Flotillin SPT16 PF08644.11 PVD27371.1 - 9.9 6.3 13.3 7.6 6.7 1.1 2.5 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) p450 PF00067.22 PVD27372.1 - 3.5e-83 279.9 0.0 4e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEM154 PF15102.6 PVD27373.1 - 3.3e-06 27.0 0.8 0.00019 21.4 0.2 2.3 2 0 0 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 PVD27373.1 - 0.0016 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Rifin Shisa PF13908.6 PVD27373.1 - 0.0039 17.5 0.7 0.0077 16.5 0.7 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 PVD27373.1 - 0.0094 16.2 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 Glycophorin A BatD PF13584.6 PVD27373.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Mucin15 PF15672.5 PVD27373.1 - 0.024 14.1 0.5 0.05 13.1 0.5 1.5 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 EphA2_TM PF14575.6 PVD27373.1 - 0.026 15.4 0.1 0.084 13.8 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 PVD27373.1 - 0.05 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 SCIMP protein 7TM_GPCR_Srv PF10323.9 PVD27373.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Syndecan PF01034.20 PVD27373.1 - 0.096 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain Bac_A_amyl_C PF18612.1 PVD27373.1 - 0.1 12.4 0.6 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial Alpha amylase C-terminal domain Adeno_E3_CR2 PF02439.15 PVD27373.1 - 0.81 9.5 6.6 0.3 10.9 1.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DSL PF01414.19 PVD27373.1 - 0.92 9.8 6.2 2.3 8.5 0.2 3.3 3 0 0 3 3 3 0 Delta serrate ligand Orf78 PF06024.12 PVD27375.1 - 0.026 14.8 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 PVD27375.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.6 PVD27375.1 - 0.11 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 SCIMP protein Syndecan PF01034.20 PVD27375.1 - 0.14 12.1 0.7 0.28 11.1 0.7 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 PVD27377.1 - 0.0047 16.3 1.2 0.007 15.8 0.4 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SAP130_C PF16014.5 PVD27377.1 - 0.07 12.2 0.1 0.099 11.7 0.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus C1-set PF07654.15 PVD27378.1 - 0.61 10.5 3.6 2.9 8.3 0.3 2.7 3 0 0 3 3 3 0 Immunoglobulin C1-set domain DUF4366 PF14283.6 PVD27379.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CRA_rpt PF07046.11 PVD27379.1 - 0.12 12.6 0.5 0.21 11.7 0.5 1.3 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Asp_protease_2 PF13650.6 PVD27380.1 - 9.6e-05 23.0 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PVD27380.1 - 0.0024 18.4 0.0 0.0046 17.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 PVD27380.1 - 0.0039 17.2 0.2 0.0087 16.1 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle 2-Hacid_dh_C PF02826.19 PVD27381.1 - 1.9e-45 154.4 0.0 2.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD27381.1 - 1.4e-30 105.7 0.0 1.6e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 PVD27381.1 - 0.0016 17.8 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 PVD27381.1 - 0.01 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 PVD27381.1 - 0.043 14.3 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PVD27381.1 - 0.072 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3188 PF11384.8 PVD27382.1 - 0.35 10.6 2.3 18 5.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) MFS_1 PF07690.16 PVD27383.1 - 1.4e-35 122.9 27.3 5.5e-22 78.2 3.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 PVD27383.1 - 2.4e-05 23.8 22.3 0.009 15.3 2.9 2.7 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 PVD27383.1 - 0.00053 18.9 11.0 0.081 11.8 0.0 2.3 2 0 0 2 2 2 2 MFS_1 like family Sulf_coat_C PF12193.8 PVD27383.1 - 0.25 11.4 1.8 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal UPF0259 PF06790.11 PVD27383.1 - 0.25 11.1 2.0 0.47 10.2 2.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0259) MFS_1 PF07690.16 PVD27384.1 - 1.7e-34 119.3 29.4 2.2e-20 72.9 8.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD27384.1 - 1.1e-08 34.8 19.2 3.3e-07 29.9 6.0 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 PVD27384.1 - 0.022 13.4 6.4 0.044 12.4 6.4 1.5 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Methyltransf_23 PF13489.6 PVD27385.1 - 0.034 14.0 0.0 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Ogr_Delta PF04606.12 PVD27385.1 - 0.045 13.7 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger MFS_1 PF07690.16 PVD27386.1 - 2.2e-39 135.4 48.6 4.4e-24 85.1 7.5 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 PVD27386.1 - 1.3e-07 31.3 7.9 1.3e-07 31.3 7.9 2.7 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 PVD27386.1 - 0.00034 19.3 5.7 0.00034 19.3 5.7 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein ATG22 PF11700.8 PVD27386.1 - 0.0084 14.8 4.7 0.015 14.0 4.7 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Gate PF07670.14 PVD27386.1 - 0.14 12.4 6.6 0.26 11.6 0.0 3.2 2 1 0 2 2 2 0 Nucleoside recognition zf-C4 PF00105.18 PVD27387.1 - 9e-19 67.7 9.5 3.6e-15 56.2 9.5 2.9 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD27387.1 - 5.1e-13 49.1 0.3 1e-12 48.1 0.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD27388.1 - 1e-12 48.3 9.3 1e-12 48.3 9.3 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD27388.1 - 4.1e-12 46.1 0.1 1.1e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hormone_recep PF00104.30 PVD27389.1 - 9.5e-13 48.2 0.5 2e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD27389.1 - 0.003 18.0 7.9 0.017 15.6 7.9 2.2 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.18 PVD27390.1 - 9.1e-25 86.9 14.2 2.2e-24 85.7 14.2 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD27390.1 - 2.9e-09 36.8 0.0 9.6e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PDCD9 PF07147.12 PVD27391.1 - 7.3e-08 32.0 0.1 3.7e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) mTERF PF02536.14 PVD27392.1 - 1.1e-05 24.5 0.1 1.3e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 mTERF FAM91_N PF14647.6 PVD27392.1 - 0.029 13.7 0.1 0.035 13.4 0.1 1.0 1 0 0 1 1 1 0 FAM91 N-terminus Patched PF02460.18 PVD27393.1 - 1.5e-112 377.3 17.0 2.5e-112 376.5 17.0 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD27393.1 - 3.3e-26 91.9 10.9 3.3e-26 91.9 10.9 3.2 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 PVD27393.1 - 0.034 11.8 11.6 0.065 10.9 11.6 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Patched PF02460.18 PVD27394.1 - 2.3e-129 432.9 6.2 2.8e-129 432.6 6.2 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PVD27394.1 - 4.1e-30 104.6 6.4 4.1e-30 104.6 6.4 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 PVD27394.1 - 0.26 10.2 28.3 0.68 8.8 10.1 3.1 3 0 0 3 3 3 0 MMPL family ACR_tran PF00873.19 PVD27394.1 - 0.33 8.5 17.6 0.71 7.5 17.6 1.5 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SKG6 PF08693.10 PVD27395.1 - 0.0055 16.1 3.4 0.01 15.2 3.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 PVD27395.1 - 0.078 12.8 2.3 0.14 12.0 2.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 PVD27395.1 - 0.16 12.1 0.5 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Podoplanin Trypan_PARP PF05887.11 PVD27397.1 - 0.00053 20.0 6.3 0.00086 19.3 6.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NERD PF08378.11 PVD27397.1 - 0.0041 17.6 0.0 0.045 14.2 0.0 2.1 2 0 0 2 2 2 1 Nuclease-related domain DEC-1_N PF04625.13 PVD27397.1 - 0.43 9.6 4.7 0.6 9.1 4.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TALPID3 PF15324.6 PVD27397.1 - 2.7 5.5 6.6 3.6 5.1 6.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target KH_1 PF00013.29 PVD27398.1 - 4.8e-12 45.5 0.0 7.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 KH domain BMC PF00936.19 PVD27398.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 BMC domain KH_2 PF07650.17 PVD27398.1 - 0.13 12.1 0.2 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 KH domain KH_1 PF00013.29 PVD27399.1 - 3.1e-06 26.9 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 PVD27399.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_2 PF07650.17 PVD27399.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 KH domain KH_1 PF00013.29 PVD27400.1 - 3.1e-13 49.3 0.1 5.4e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PVD27400.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 KH domain ketoacyl-synt PF00109.26 PVD27401.1 - 2.9e-63 213.8 0.1 3.1e-41 141.6 0.0 3.1 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PVD27401.1 - 4.1e-49 166.9 0.0 8.5e-49 165.9 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 PVD27401.1 - 3.7e-45 154.8 0.0 6.3e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 PVD27401.1 - 1.1e-35 122.1 0.3 2.7e-35 120.9 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 PVD27401.1 - 7.7e-28 97.6 0.0 1.3e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 PVD27401.1 - 1.8e-12 47.7 0.0 4.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 PVD27401.1 - 1.8e-10 41.0 0.7 5.3e-10 39.5 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD27401.1 - 2.6e-08 33.6 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD27401.1 - 1e-05 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD27402.1 - 3.7e-49 167.1 0.0 5.9e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PVD27402.1 - 1e-10 41.4 0.0 2.2e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 PVD27402.1 - 1.4e-10 41.3 0.2 3.1e-10 40.3 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 PVD27402.1 - 8.5e-09 35.3 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 PVD27402.1 - 0.012 14.7 0.0 0.027 13.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ketoacyl-synt PF00109.26 PVD27403.1 - 4.1e-84 282.1 0.2 6.5e-84 281.4 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PVD27403.1 - 4e-29 101.0 2.8 1.6e-21 76.5 0.1 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PVD27403.1 - 1e-05 25.1 0.6 1e-05 25.1 0.6 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.21 PVD27403.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain zf-C2H2_4 PF13894.6 PVD27404.1 - 5.3e-19 67.3 68.0 0.0098 16.7 0.6 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD27404.1 - 1.9e-18 65.8 62.4 0.00051 20.3 0.5 9.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD27404.1 - 2.1e-18 65.9 76.9 1.9e-07 31.2 3.9 10.5 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD27404.1 - 5e-07 29.6 2.6 2.2e-05 24.3 0.3 9.0 9 1 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD27404.1 - 1.3e-06 28.5 35.1 0.65 10.4 0.6 8.8 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 PVD27404.1 - 0.0045 17.3 0.6 0.0045 17.3 0.6 3.9 3 1 1 4 4 4 1 zinc-finger-containing domain GAGA PF09237.11 PVD27404.1 - 0.014 15.2 13.5 5.8 6.8 0.2 4.9 4 0 0 4 4 4 0 GAGA factor Zn-C2H2_12 PF18112.1 PVD27404.1 - 0.48 10.9 7.5 8.2 7.0 0.6 4.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain FYVE PF01363.21 PVD27404.1 - 1.6 8.9 42.3 5.6 7.2 2.7 6.0 2 2 1 3 3 3 0 FYVE zinc finger Herpes_UL73 PF03554.13 PVD27409.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF2694 PF10904.8 PVD27409.1 - 0.098 12.7 0.3 0.34 11.0 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2694) PDEase_I PF00233.19 PVD27419.1 - 9.1e-80 267.8 1.1 1.2e-79 267.4 1.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PVD27419.1 - 0.04 14.1 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 HD domain ABC_membrane PF00664.23 PVD27421.1 - 4.8e-17 62.5 7.4 4.8e-17 62.5 7.4 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF347 PF03988.12 PVD27421.1 - 2.4 8.4 5.8 25 5.1 0.4 3.6 4 0 0 4 4 4 0 Repeat of Unknown Function (DUF347) ABC_tran PF00005.27 PVD27422.1 - 1.4e-44 152.0 0.0 6.2e-18 65.6 0.0 3.4 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 PVD27422.1 - 2.8e-44 151.8 14.8 3.2e-36 125.4 10.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 PVD27422.1 - 3.7e-05 23.8 0.3 0.34 11.0 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 PVD27422.1 - 5e-05 22.8 1.5 0.14 11.6 0.1 4.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27422.1 - 0.00018 21.9 0.1 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 PVD27422.1 - 0.0005 20.2 0.4 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 PVD27422.1 - 0.0019 17.8 0.6 0.12 12.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PVD27422.1 - 0.0032 17.4 1.5 0.51 10.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 PVD27422.1 - 0.01 15.5 4.2 0.35 10.6 0.1 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PVD27422.1 - 0.017 15.4 0.3 3.1 8.1 0.2 2.8 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 PVD27422.1 - 0.043 13.3 0.2 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 PVD27422.1 - 0.044 13.4 1.1 0.35 10.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 PVD27422.1 - 0.052 13.3 1.5 6 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 PVD27422.1 - 0.061 13.4 4.5 0.39 10.8 0.3 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 PVD27422.1 - 0.077 13.5 0.4 19 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 PVD27422.1 - 0.08 12.7 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 PVD27422.1 - 0.083 12.8 0.1 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 PVD27422.1 - 0.12 12.0 0.1 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PVD27422.1 - 0.15 11.0 0.0 9.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 PVD27422.1 - 0.22 12.0 0.1 8.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD27423.1 - 3.1e-08 34.2 0.0 4.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD27423.1 - 0.00093 18.7 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PVD27423.1 - 0.024 13.4 0.0 0.026 13.4 0.0 1.0 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF1815 PF08844.10 PVD27423.1 - 0.025 14.6 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) DEAD PF00270.29 PVD27423.1 - 0.052 13.3 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase ABC_membrane PF00664.23 PVD27424.1 - 1.4e-59 202.0 39.2 4.1e-35 121.8 19.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27424.1 - 5.3e-39 133.9 0.1 1.3e-26 93.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27424.1 - 1.7e-06 27.6 0.1 0.0019 17.7 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain CbiA PF01656.23 PVD27424.1 - 0.01 15.9 0.0 1.3 9.1 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 PVD27424.1 - 0.041 14.0 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 PVD27424.1 - 0.068 13.3 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 PVD27424.1 - 0.15 11.7 0.1 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 PVD27424.1 - 0.2 11.4 0.9 2.5 7.8 0.9 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase ABC_membrane PF00664.23 PVD27425.1 - 4.4e-59 200.4 43.1 3.7e-40 138.3 20.5 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27425.1 - 7.7e-32 110.7 1.1 1.1e-21 77.7 0.0 3.0 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 PVD27425.1 - 6.2e-06 26.3 0.4 0.049 13.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 PVD27425.1 - 7.1e-06 25.6 2.2 0.15 11.4 0.2 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27425.1 - 5.7e-05 23.6 0.1 0.0092 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PVD27425.1 - 7.5e-05 22.7 0.8 0.0033 17.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 PVD27425.1 - 0.00017 21.2 1.1 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 PVD27425.1 - 0.00072 20.1 6.6 0.33 11.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 PVD27425.1 - 0.00092 19.1 0.2 0.35 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 PVD27425.1 - 0.0065 15.6 1.4 2 7.4 0.0 3.2 2 1 0 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 PVD27425.1 - 0.014 14.9 0.1 1.9 8.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 PVD27425.1 - 0.015 14.3 0.7 0.47 9.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 PVD27425.1 - 0.017 14.8 0.0 0.77 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PVD27425.1 - 0.023 14.8 0.2 0.023 14.8 0.2 3.2 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 PVD27425.1 - 0.027 14.6 0.2 0.027 14.6 0.2 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain NB-ARC PF00931.22 PVD27425.1 - 0.029 13.6 0.4 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.7 PVD27425.1 - 0.035 13.0 0.2 5 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 PVD27425.1 - 0.039 14.2 0.1 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain FAM76 PF16046.5 PVD27425.1 - 0.06 12.7 1.8 0.12 11.7 1.8 1.4 1 0 0 1 1 1 0 FAM76 protein Zeta_toxin PF06414.12 PVD27425.1 - 0.066 12.5 0.4 0.3 10.3 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 PVD27425.1 - 0.069 12.7 1.0 0.47 10.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 PVD27425.1 - 0.11 12.2 0.1 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 PVD27425.1 - 0.12 11.9 0.2 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain LptF_LptG PF03739.14 PVD27425.1 - 3 6.6 17.9 13 4.5 3.0 3.8 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG AAA_15 PF13175.6 PVD27425.1 - 8.3 6.0 9.3 1.3 8.6 0.1 3.3 3 1 0 3 3 2 0 AAA ATPase domain ABC_tran PF00005.27 PVD27426.1 - 1.5e-09 38.4 0.0 2.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD27426.1 - 0.00015 21.3 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PVD27426.1 - 0.023 13.5 0.0 0.028 13.2 0.0 1.0 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DEAD PF00270.29 PVD27426.1 - 0.023 14.4 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-C4 PF00105.18 PVD27427.1 - 4.8e-24 84.6 12.5 1.1e-23 83.5 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD27427.1 - 0.00026 20.7 0.5 0.00049 19.7 0.5 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Vps36-NZF-N PF16988.5 PVD27427.1 - 0.072 12.5 1.3 5.1 6.6 0.3 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ABC_membrane PF00664.23 PVD27428.1 - 8.5e-54 183.0 31.9 1.3e-43 149.6 16.3 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27428.1 - 1.1e-47 162.0 2.4 4.4e-28 98.5 0.0 3.6 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 PVD27428.1 - 2.5e-07 30.4 8.5 0.01 15.3 0.1 4.4 2 2 2 5 5 5 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27428.1 - 9e-07 29.0 1.2 0.038 14.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27428.1 - 3.3e-05 23.9 1.6 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PVD27428.1 - 0.00013 22.4 0.3 0.24 11.7 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 PVD27428.1 - 0.0013 18.9 2.4 0.011 15.8 0.2 2.6 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 PVD27428.1 - 0.0015 17.8 3.5 0.12 11.6 0.3 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 PVD27428.1 - 0.0043 17.6 1.6 1.5 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 PVD27428.1 - 0.006 15.8 0.4 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 PVD27428.1 - 0.0066 16.2 3.3 1.2 8.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD27428.1 - 0.007 16.2 3.6 1.6 8.5 0.0 3.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 PVD27428.1 - 0.016 14.9 0.3 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD27428.1 - 0.03 14.0 5.3 1.5 8.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PVD27428.1 - 0.041 14.2 1.2 9.1 6.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PVD27428.1 - 0.083 12.4 1.5 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 PVD27428.1 - 0.089 13.0 0.6 18 5.6 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 PVD27428.1 - 0.11 11.2 0.6 0.23 10.3 0.6 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF87 PF01935.17 PVD27428.1 - 0.17 12.0 7.5 2.4 8.2 1.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 PVD27428.1 - 0.29 10.8 1.1 15 5.2 0.1 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.22 PVD27428.1 - 0.7 9.0 3.6 4.5 6.4 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 PVD27428.1 - 0.76 8.7 4.2 2.8 6.8 1.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB C2-set_2 PF08205.12 PVD27429.1 - 0.00025 21.1 0.0 0.19 11.8 0.0 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Hid1 PF12722.7 PVD27429.1 - 0.11 10.6 10.4 0.16 10.0 10.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phage_Gp23 PF10669.9 PVD27429.1 - 2.2 8.7 5.6 1.8 8.9 0.1 2.8 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) V-set PF07686.17 PVD27432.1 - 0.043 14.0 0.5 23 5.2 0.1 3.2 3 0 0 3 3 3 0 Immunoglobulin V-set domain DUF357 PF04010.13 PVD27432.1 - 0.12 12.4 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Kringle PF00051.18 PVD27434.1 - 7.1e-36 122.4 38.5 6.1e-12 45.7 3.1 4.4 4 0 0 4 4 4 4 Kringle domain DUF3719 PF12516.8 PVD27434.1 - 0.0085 15.8 0.0 5.8 6.7 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3719) RAG2_PHD PF13341.6 PVD27434.1 - 0.036 14.1 2.9 1.6 8.9 0.1 2.7 2 0 0 2 2 2 0 RAG2 PHD domain PAS_7 PF12860.7 PVD27434.1 - 0.11 12.6 0.0 24 5.1 0.0 2.5 2 0 0 2 2 2 0 PAS fold MC1 PF05854.11 PVD27434.1 - 0.21 11.9 0.2 47 4.4 0.0 2.8 2 0 0 2 2 2 0 Non-histone chromosomal protein MC1 Ig_3 PF13927.6 PVD27436.1 - 1.7e-48 163.1 2.9 2.2e-11 44.2 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 PVD27436.1 - 4.6e-35 119.8 0.6 4.6e-07 30.1 0.1 5.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 PVD27436.1 - 5e-34 116.2 0.0 4.2e-10 39.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 PVD27436.1 - 1.3e-23 82.9 0.2 0.00012 22.2 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 PVD27436.1 - 2e-17 63.0 0.1 1.4e-07 31.4 0.0 5.3 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27436.1 - 9.8e-13 48.2 1.4 2.7e-05 24.3 0.0 5.2 5 1 1 6 6 6 2 Immunoglobulin V-set domain C1-set PF07654.15 PVD27436.1 - 5.8e-06 26.6 0.8 0.064 13.6 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 PVD27436.1 - 0.0025 17.8 0.0 2.5 8.2 0.0 2.8 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 PVD27436.1 - 0.0029 18.0 8.2 3.2 8.2 0.0 6.1 6 2 0 6 6 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD27436.1 - 0.0048 17.1 2.3 40 4.6 0.0 5.7 6 1 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 PVD27436.1 - 0.089 13.0 0.0 7.4 6.8 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 PVD27436.1 - 0.11 12.4 0.0 2.2 8.3 0.0 2.9 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain DUF4795 PF16043.5 PVD27437.1 - 3.3e-09 36.7 8.8 3.3e-09 36.7 8.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) UvrD-helicase PF00580.21 PVD27437.1 - 0.024 14.2 3.9 0.04 13.4 3.9 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Pox_A11 PF05061.13 PVD27437.1 - 0.23 10.7 6.5 3.2 6.9 0.1 2.7 2 1 0 2 2 2 0 Poxvirus A11 Protein HTH_IclR PF09339.10 PVD27437.1 - 0.36 10.7 1.5 3.3 7.6 0.4 3.0 4 0 0 4 4 4 0 IclR helix-turn-helix domain ATAD4 PF15321.6 PVD27437.1 - 3.5 9.0 7.3 8.8 7.7 0.0 2.6 1 1 0 2 2 2 0 ATPase family AAA domain containing 4 DUF3847 PF12958.7 PVD27438.1 - 0.024 14.7 0.9 0.15 12.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Laminin_II PF06009.12 PVD27439.1 - 0.034 14.2 4.1 0.21 11.6 2.1 2.2 1 1 1 2 2 2 0 Laminin Domain II RmuC PF02646.16 PVD27439.1 - 0.034 13.3 2.2 0.044 12.9 0.9 1.7 1 1 1 2 2 2 0 RmuC family DUF4315 PF14193.6 PVD27439.1 - 0.055 13.5 0.1 0.4 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) NPV_P10 PF05531.12 PVD27439.1 - 0.11 13.0 5.9 0.42 11.1 2.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 PVD27439.1 - 0.21 11.4 5.3 0.12 12.2 1.4 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Tropomyosin_1 PF12718.7 PVD27439.1 - 0.49 10.5 4.3 0.89 9.7 4.3 1.5 1 1 0 1 1 1 0 Tropomyosin like Syntaxin_2 PF14523.6 PVD27439.1 - 1.1 9.7 5.8 1.7 9.1 1.5 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Holin_BhlA PF10960.8 PVD27439.1 - 1.5 8.8 4.5 1.7 8.7 2.3 2.2 1 1 1 2 2 2 0 BhlA holin family DUF1664 PF07889.12 PVD27439.1 - 2 8.5 5.7 2.3 8.3 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 PVD27439.1 - 3.6 7.8 8.2 0.54 10.5 3.9 1.9 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CwfJ_C_1 PF04677.15 PVD27440.1 - 1.6e-37 128.1 1.5 2.6e-37 127.4 1.5 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 PVD27440.1 - 2.7e-20 73.1 1.1 6.5e-19 68.7 1.1 3.1 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 PVD27441.1 - 2.6e-37 127.4 1.5 4.8e-37 126.5 1.5 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 PVD27441.1 - 1.8e-31 108.9 0.1 1.8e-31 108.9 0.1 3.4 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Mit_KHE1 PF10173.9 PVD27441.1 - 4.1 7.4 18.2 0.23 11.5 12.0 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related V-set PF07686.17 PVD27442.1 - 0.0018 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 PVD27442.1 - 0.0064 16.6 0.1 0.023 14.9 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27442.1 - 0.007 16.9 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27442.1 - 0.01 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27442.1 - 0.028 14.7 0.1 0.056 13.8 0.1 1.5 1 1 0 1 1 1 0 Immunoglobulin domain NADH_u_ox_C PF12853.7 PVD27442.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit fn3 PF00041.21 PVD27443.1 - 4.4e-05 23.8 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain TMEM154 PF15102.6 PVD27443.1 - 0.023 14.6 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family OATP PF03137.20 PVD27444.1 - 4.4e-118 394.9 9.1 3e-99 332.8 5.5 2.0 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD27444.1 - 1.5e-16 60.3 28.4 7.8e-14 51.4 11.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Pam17 PF08566.10 PVD27444.1 - 0.091 12.6 1.1 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Colicin_V PF02674.16 PVD27444.1 - 5.6 6.9 14.7 0.1 12.6 0.6 3.9 4 1 0 4 4 4 0 Colicin V production protein Kringle PF00051.18 PVD27445.1 - 4.6e-16 58.9 4.2 4.6e-16 58.9 4.2 2.0 2 0 0 2 2 2 1 Kringle domain V-set PF07686.17 PVD27447.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin V-set domain RSN1_TM PF13967.6 PVD27447.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF4231 PF14015.6 PVD27447.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) EphA2_TM PF14575.6 PVD27447.1 - 0.18 12.7 0.0 0.33 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD27447.1 - 0.23 11.6 4.5 0.47 10.6 4.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PARM PF17061.5 PVD27447.1 - 0.55 10.3 7.3 0.97 9.5 7.3 1.3 1 0 0 1 1 1 0 PARM FUN14 PF04930.15 PVD27447.1 - 5.9 7.4 6.0 5.5 7.5 0.0 2.3 2 0 0 2 2 2 0 FUN14 family TIG PF01833.24 PVD27448.1 - 3.3e-133 434.1 147.2 2.7e-15 56.2 1.1 16.5 17 0 0 17 17 17 13 IPT/TIG domain G8 PF10162.9 PVD27448.1 - 1.9e-50 170.1 0.0 1.4e-23 83.3 0.0 3.8 3 0 0 3 3 3 2 G8 domain Beta_helix PF13229.6 PVD27448.1 - 1.7e-05 24.7 22.1 3.8e-05 23.6 0.0 5.4 3 2 0 3 3 3 2 Right handed beta helix region PA14 PF07691.12 PVD27448.1 - 0.023 14.5 1.1 2.5 7.9 0.1 2.9 2 0 0 2 2 2 0 PA14 domain DUF4173 PF13777.6 PVD27449.1 - 0.00042 19.8 10.5 0.22 10.9 0.3 4.9 1 1 3 4 4 4 4 Domain of unknown function (DUF4173) AbiEi_4 PF13338.6 PVD27449.1 - 0.13 12.4 3.4 1.6e+02 2.6 0.1 5.6 1 1 4 5 5 5 0 Transcriptional regulator, AbiEi antitoxin Glucodextran_B PF09136.10 PVD27449.1 - 0.2 12.0 2.5 3.9 7.9 0.8 2.1 1 1 1 2 2 2 0 Glucodextranase, domain B DUF4764 PF15961.5 PVD27449.1 - 1.8 7.2 8.7 2.1 7.0 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Tetraspanin PF00335.20 PVD27450.1 - 2.1e-08 34.2 16.4 2.8e-07 30.5 16.4 2.5 1 1 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 PVD27451.1 - 4.8e-14 52.6 17.0 1e-12 48.3 17.0 2.3 1 1 0 1 1 1 1 Tetraspanin family DUF2157 PF09925.9 PVD27451.1 - 0.043 13.6 1.6 0.069 12.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4064 PF13273.6 PVD27451.1 - 0.62 10.4 14.0 0.091 13.0 6.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) MFS_1 PF07690.16 PVD27452.1 - 0.0028 16.7 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_14 PF01607.24 PVD27453.1 - 6.6e-07 29.4 1.9 9e-07 29.0 1.9 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 PVD27453.1 - 0.011 13.9 0.5 0.014 13.5 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SCAN PF02023.17 PVD27454.1 - 1.6e-08 34.2 0.0 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 PVD27454.1 - 0.04 14.0 1.8 0.081 13.0 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 PVD27454.1 - 0.14 12.8 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease VWA PF00092.28 PVD27455.1 - 2.8e-28 99.3 0.1 3.8e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD27455.1 - 8.4e-14 52.1 0.4 7.4e-13 49.1 0.4 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD27455.1 - 0.035 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF99 PF01949.16 PVD27455.1 - 0.14 11.5 0.3 24 4.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF99 VWA PF00092.28 PVD27456.1 - 1.2e-33 116.8 0.1 1.7e-33 116.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD27456.1 - 2.7e-15 56.9 0.1 5e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD27456.1 - 8e-13 48.3 11.0 0.0015 18.6 1.3 3.8 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain VWA_3 PF13768.6 PVD27456.1 - 0.0013 18.7 0.2 0.0037 17.2 0.2 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Pribosyl_synth PF14572.6 PVD27456.1 - 0.02 14.9 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain VWA_CoxE PF05762.14 PVD27456.1 - 0.027 13.9 4.1 0.078 12.4 4.1 1.6 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1194 PF06707.11 PVD27456.1 - 1.1 8.5 4.3 5.7 6.1 4.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1194) VWA PF00092.28 PVD27457.1 - 8.8e-38 130.3 1.0 1.9e-37 129.2 0.8 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD27457.1 - 1.4e-15 57.8 0.2 2.9e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD27457.1 - 2.6e-14 53.1 18.8 7.1e-06 26.1 0.3 3.9 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain Ets PF00178.22 PVD27458.1 - 5.5e-34 116.5 0.2 8.9e-34 115.8 0.2 1.3 1 0 0 1 1 1 1 Ets-domain Ets PF00178.22 PVD27459.1 - 8.5e-36 122.3 0.3 1.6e-35 121.4 0.3 1.4 1 0 0 1 1 1 1 Ets-domain Nop52 PF05997.12 PVD27460.1 - 1e-50 172.5 0.2 2.4e-50 171.3 0.1 1.6 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Ammonium_transp PF00909.21 PVD27461.1 - 1.5e-74 251.1 17.5 1.8e-74 250.8 17.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family BTG PF07742.12 PVD27462.1 - 6.9e-34 116.2 0.0 1.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 BTG family Hormone_recep PF00104.30 PVD27463.1 - 3.4e-28 98.7 0.3 4.8e-28 98.1 0.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPR_5 PF12688.7 PVD27464.1 - 0.036 14.3 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat SID-1_RNA_chan PF13965.6 PVD27465.1 - 1.9e-222 740.0 22.2 2.5e-222 739.6 22.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 rve PF00665.26 PVD27466.1 - 1.5e-16 60.6 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RAMPs PF03787.15 PVD27466.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 RAMP superfamily DUF2688 PF10892.8 PVD27466.1 - 0.12 11.8 0.9 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) VWA PF00092.28 PVD27470.1 - 7e-09 36.2 0.0 1.5e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.20 PVD27470.1 - 8.7e-05 23.0 12.4 0.00047 20.7 4.1 3.4 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) cEGF PF12662.7 PVD27470.1 - 0.06 13.3 6.5 0.097 12.6 0.7 3.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like fn3 PF00041.21 PVD27471.1 - 1e-09 38.6 8.8 0.042 14.2 0.0 8.9 11 0 0 11 11 11 3 Fibronectin type III domain PKD PF00801.20 PVD27471.1 - 2.3 8.1 13.1 2.2 8.2 0.1 6.3 7 0 0 7 7 7 0 PKD domain PIH1_CS PF18201.1 PVD27472.1 - 9.3e-13 48.4 0.7 1.6e-12 47.7 0.7 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 PVD27472.1 - 4.9e-05 22.9 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain DUF493 PF04359.14 PVD27472.1 - 0.049 14.2 0.1 0.094 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF493) NKAP PF15692.5 PVD27473.1 - 4.8e-13 49.6 3.6 4.8e-13 49.6 3.6 2.3 1 1 1 2 2 2 1 NF-kappa-B-activating protein Spem1 PF15670.5 PVD27473.1 - 1.3 8.5 6.3 2 7.9 6.3 1.3 1 1 0 1 1 1 0 Spermatid maturation protein 1 PIH1_CS PF18201.1 PVD27474.1 - 1.3e-12 47.9 0.9 2.4e-12 47.1 0.9 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 PVD27474.1 - 1.3e-11 44.2 0.3 4.2e-11 42.6 0.3 1.8 1 1 0 1 1 1 1 PIH1 N-terminal domain Ig_3 PF13927.6 PVD27478.1 - 7.9e-65 215.4 21.4 8.1e-15 55.2 2.4 6.8 6 1 1 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 PVD27478.1 - 8.6e-53 176.6 17.0 4.1e-14 52.7 0.1 6.4 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD27478.1 - 4.9e-52 173.9 9.0 4.7e-11 42.6 0.1 7.4 5 2 1 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 PVD27478.1 - 2.7e-41 139.6 17.8 1.2e-08 35.0 0.3 7.0 6 2 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 PVD27478.1 - 5.2e-19 68.4 26.1 5.3e-07 29.8 0.1 9.2 6 4 2 9 9 9 3 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD27478.1 - 1.5e-17 63.8 0.4 0.0017 18.7 0.0 5.9 6 0 0 6 6 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3 PF00041.21 PVD27478.1 - 1.1e-12 48.1 3.8 6.7e-12 45.6 0.0 3.7 4 0 0 4 4 4 1 Fibronectin type III domain Ig_6 PF18452.1 PVD27478.1 - 4.1e-12 45.5 0.1 0.015 14.9 0.0 5.6 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 PVD27478.1 - 1e-11 44.9 2.2 0.061 13.6 0.0 6.2 6 1 0 6 6 6 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD27478.1 - 1.3e-11 44.4 7.1 8.1e-08 32.2 0.0 4.6 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD27478.1 - 6.2e-10 39.0 0.0 2.8 8.1 0.0 5.6 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27478.1 - 3.8e-07 30.1 3.0 1.5 8.9 0.1 6.2 6 0 0 6 6 6 1 C17orf99 Ig domain V-set_CD47 PF08204.11 PVD27478.1 - 5.3e-06 26.4 3.6 3.6 7.6 0.0 5.7 6 0 0 6 6 6 1 CD47 immunoglobulin-like domain C1-set PF07654.15 PVD27478.1 - 0.0055 17.0 11.3 0.7 10.3 0.0 5.5 5 2 0 5 5 4 1 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 PVD27478.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.8 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain DUF4051 PF13260.6 PVD27480.1 - 0.048 13.4 0.1 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) HMG_box PF00505.19 PVD27481.1 - 1.5e-16 60.5 0.2 3e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD27481.1 - 6.5e-08 33.0 0.2 1.2e-07 32.2 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain DUF2028 PF09667.10 PVD27481.1 - 9.1e-07 29.0 1.6 4.7e-06 26.7 1.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2028) Dicty_CTDC PF00526.18 PVD27482.1 - 0.014 15.3 1.5 0.1 12.5 0.1 2.5 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat LELP1 PF15042.6 PVD27482.1 - 0.22 11.9 7.9 0.26 11.7 6.8 1.7 1 1 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 ATP-synt_F6 PF05511.11 PVD27483.1 - 5.5e-29 100.5 0.1 5.7e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 PVD27483.1 - 0.034 14.1 0.4 0.22 11.5 0.4 2.0 1 1 0 1 1 1 0 ATP synthase complex subunit h Ets PF00178.22 PVD27484.1 - 4.6e-35 119.9 0.8 1e-34 118.9 0.8 1.6 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.8 PVD27484.1 - 1.2e-32 111.9 0.7 2.3e-32 111.0 0.7 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 PVD27484.1 - 4.1e-29 100.4 0.1 9.2e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain MACPF PF01823.19 PVD27485.1 - 2.9e-16 60.2 0.0 1.3e-15 58.0 0.0 2.0 2 1 0 2 2 2 1 MAC/Perforin domain EB PF01683.18 PVD27485.1 - 0.00033 20.9 2.0 0.00033 20.9 2.0 2.9 3 0 0 3 3 3 1 EB module PAN_4 PF14295.6 PVD27485.1 - 0.00067 19.5 0.3 0.00067 19.5 0.3 4.1 4 0 0 4 4 4 1 PAN domain zf-ZPR1 PF03367.13 PVD27486.1 - 2.4e-103 342.7 0.7 3e-56 189.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 PVD27486.1 - 0.09 12.9 3.7 2 8.6 0.1 2.6 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type UPF0547 PF10571.9 PVD27486.1 - 2.7 8.2 10.9 10 6.3 2.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Porin_3 PF01459.22 PVD27487.1 - 1.2e-73 248.0 0.2 1.3e-73 247.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.8 PVD27487.1 - 0.012 14.6 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 APOBEC4 PF18775.1 PVD27488.1 - 0.007 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 APOBEC4 PI-PLC-X PF00388.19 PVD27488.1 - 0.029 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Varsurf_PPLC PF03490.13 PVD27488.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C PT PF04886.12 PVD27490.1 - 1.8e-09 37.0 3.8 0.091 12.3 0.4 5.2 2 2 2 4 4 4 4 PT repeat DUF3194 PF11419.8 PVD27490.1 - 0.00014 22.2 1.6 8.2 6.9 0.2 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3194) MspA PF09203.11 PVD27490.1 - 0.011 15.6 5.6 16 5.3 5.6 2.9 1 1 0 1 1 1 0 MspA TMEM154 PF15102.6 PVD27490.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family FtsL PF04999.13 PVD27490.1 - 0.29 11.2 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Cell division protein FtsL DUF4744 PF15918.5 PVD27491.1 - 0.0044 17.8 10.9 0.0044 17.8 10.9 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) SNAP PF14938.6 PVD27491.1 - 0.027 13.9 0.2 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PMG PF05287.12 PVD27492.1 - 7e-05 22.9 43.6 0.0017 18.4 37.3 2.5 1 1 1 2 2 2 2 PMG protein Pentapeptide_4 PF13599.6 PVD27492.1 - 0.00022 21.3 4.8 0.11 12.7 0.3 2.9 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) Keratin_B2_2 PF13885.6 PVD27492.1 - 0.0019 18.1 56.3 0.45 10.5 8.3 4.4 1 1 1 2 2 2 1 Keratin, high sulfur B2 protein NHase_beta PF02211.15 PVD27492.1 - 0.21 11.6 0.0 33 4.4 0.0 3.1 1 1 1 2 2 2 0 Nitrile hydratase beta subunit LolA_like PF17131.4 PVD27492.1 - 8.3 6.1 5.5 6.6e+02 -0.1 5.5 3.5 1 1 0 1 1 1 0 Outer membrane lipoprotein-sorting protein DUF3439 PF11921.8 PVD27494.1 - 0.024 14.6 2.4 0.024 14.6 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4175 PF13779.6 PVD27494.1 - 0.42 8.5 3.4 0.23 9.3 1.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) LPG_synthase_TM PF03706.13 PVD27496.1 - 0.027 14.0 0.2 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region LapA_dom PF06305.11 PVD27496.1 - 0.059 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 PVD27498.1 - 5.6e-28 97.7 0.0 1.2e-27 96.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD27498.1 - 5.5e-24 85.0 0.0 8e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD27498.1 - 0.0061 16.5 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4448 PF14610.6 PVD27499.1 - 0.029 14.2 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RAMP PF04901.13 PVD27499.1 - 0.057 13.4 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Receptor activity modifying family TMEM154 PF15102.6 PVD27499.1 - 0.087 12.7 1.3 0.13 12.1 1.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.18 PVD27501.1 - 0.0075 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A LapA_dom PF06305.11 PVD27501.1 - 0.025 14.4 1.7 0.062 13.1 1.7 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain 7tm_1 PF00001.21 PVD27501.1 - 0.053 12.8 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) CPP1-like PF11833.8 PVD27501.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TMEM154 PF15102.6 PVD27501.1 - 0.098 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Fibrinogen_C PF00147.18 PVD27502.1 - 1.2e-23 84.1 3.3 1.3e-23 84.0 3.3 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MACPF PF01823.19 PVD27503.1 - 3.3e-19 69.8 0.0 6.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 MAC/Perforin domain EB PF01683.18 PVD27503.1 - 2.1e-06 27.9 10.0 6.9e-05 23.1 1.3 4.4 5 0 0 5 5 5 2 EB module PAN_3 PF08277.12 PVD27503.1 - 9.9e-05 22.1 7.8 0.023 14.5 1.5 2.9 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.11 PVD27503.1 - 0.00098 19.2 0.1 0.00098 19.2 0.1 3.7 5 0 0 5 5 5 1 PAN-like domain SP_C-Propep PF08999.10 PVD27503.1 - 0.023 14.5 5.3 0.065 13.0 5.3 1.8 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PAN_4 PF14295.6 PVD27503.1 - 0.024 14.5 0.4 0.024 14.5 0.4 3.4 3 0 0 3 3 3 0 PAN domain STAG PF08514.11 PVD27503.1 - 0.43 10.5 4.0 1.1 9.2 0.5 2.8 2 0 0 2 2 2 0 STAG domain Fibrinogen_C PF00147.18 PVD27504.1 - 4e-26 92.2 3.0 4.2e-26 92.1 3.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Shisa PF13908.6 PVD27505.1 - 0.0018 18.5 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 PVD27505.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 PVD27505.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 PVD27505.1 - 0.11 12.0 1.0 0.21 11.2 1.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 PVD27505.1 - 0.16 12.8 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-Di19 PF05605.12 PVD27506.1 - 1.2e-05 25.5 2.8 0.053 13.8 1.0 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 PVD27506.1 - 0.00041 20.7 0.3 0.00041 20.7 0.3 4.1 4 1 0 4 4 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD27506.1 - 0.053 14.0 0.1 0.053 14.0 0.1 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type ARS2 PF04959.13 PVD27506.1 - 0.15 12.4 0.3 0.15 12.4 0.3 2.2 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf_UBZ PF18439.1 PVD27506.1 - 0.18 11.4 0.2 0.18 11.4 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-DNA_Pol PF08996.10 PVD27506.1 - 0.33 10.7 4.3 17 5.1 1.6 3.0 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.6 PVD27506.1 - 0.44 11.5 0.2 0.44 11.5 0.2 4.5 5 0 0 5 5 4 0 C2H2-type zinc finger FYDLN_acid PF09538.10 PVD27506.1 - 0.48 11.1 0.1 0.48 11.1 0.1 2.7 2 1 2 4 4 3 0 Protein of unknown function (FYDLN_acid) Rpr2 PF04032.16 PVD27506.1 - 0.55 10.5 8.6 5.3 7.4 0.2 2.8 2 2 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC_2 PF13913.6 PVD27506.1 - 1.2 9.1 5.9 17 5.4 4.2 2.9 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Nudix_N_2 PF14803.6 PVD27506.1 - 1.6 8.7 10.0 2 8.4 0.2 3.5 3 0 0 3 3 3 0 Nudix N-terminal IBR PF01485.21 PVD27506.1 - 2.1 8.6 13.4 0.16 12.2 3.5 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 PVD27506.1 - 3.8 7.1 10.9 0.8 9.3 0.5 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-CCHC_5 PF14787.6 PVD27506.1 - 7.5 6.4 9.1 1.7 8.4 2.1 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-TRAF PF02176.18 PVD27506.1 - 7.8 7.3 11.7 0.91 10.3 0.3 2.9 2 1 1 3 3 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 PVD27507.1 - 4.8e-23 80.5 60.0 1.4e-08 34.7 0.3 7.9 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD27507.1 - 2.4e-15 56.0 79.5 1.2e-06 28.6 1.8 7.9 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27507.1 - 1.4e-13 50.4 70.5 0.00041 20.9 1.0 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-Di19 PF05605.12 PVD27507.1 - 3.1e-05 24.2 10.3 0.00034 20.8 2.0 6.3 4 2 2 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 PVD27507.1 - 0.00046 20.5 3.2 0.019 15.4 0.4 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 PVD27507.1 - 0.0034 17.1 0.2 0.0034 17.1 0.2 8.8 8 3 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 PVD27507.1 - 0.018 15.1 0.3 0.018 15.1 0.3 7.9 9 0 0 9 9 9 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD27508.1 - 4.2e-34 115.5 51.7 2.1e-08 34.2 1.2 9.2 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.26 PVD27508.1 - 1.2e-23 82.1 60.0 0.00029 21.1 0.5 8.6 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27508.1 - 5.2e-21 73.5 57.3 0.0013 19.4 0.4 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD27508.1 - 6.6e-11 41.9 40.1 0.0012 18.8 0.1 7.9 8 0 0 8 8 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD27508.1 - 2.9e-08 33.8 29.3 0.0096 16.2 0.1 7.2 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD27508.1 - 0.0038 17.5 1.8 0.0038 17.5 1.8 5.3 2 2 2 5 5 5 1 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 PVD27508.1 - 0.0044 16.9 30.3 0.088 12.7 0.2 6.2 3 3 3 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.7 PVD27508.1 - 0.011 16.1 32.7 0.88 10.0 0.1 7.3 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD27508.1 - 0.033 14.0 30.2 0.094 12.5 0.2 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 PVD27508.1 - 0.07 13.9 18.8 0.85 10.4 0.4 4.3 2 1 1 3 3 3 0 zinc-ribbon family DUF3268 PF11672.8 PVD27508.1 - 0.094 13.0 0.5 0.094 13.0 0.5 3.7 2 1 2 5 5 4 0 zinc-finger-containing domain DUF2321 PF10083.9 PVD27508.1 - 0.099 12.3 9.0 1.5 8.5 0.2 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) ADK_lid PF05191.14 PVD27508.1 - 0.11 12.5 20.1 0.14 12.1 0.5 4.6 3 2 0 3 3 3 0 Adenylate kinase, active site lid Actin_micro PF17003.5 PVD27508.1 - 0.13 11.4 0.0 0.13 11.4 0.0 4.7 1 1 3 4 4 4 0 Putative actin-like family BolA PF01722.18 PVD27508.1 - 0.14 12.5 7.2 8.5 6.7 0.2 4.6 4 1 2 6 6 5 0 BolA-like protein Elf1 PF05129.13 PVD27508.1 - 0.17 12.0 24.9 0.033 14.2 2.2 4.5 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like ARS2 PF04959.13 PVD27508.1 - 0.18 12.2 3.7 4.5 7.6 0.9 2.4 2 0 0 2 2 2 0 Arsenite-resistance protein 2 GAGA PF09237.11 PVD27508.1 - 0.24 11.3 7.5 8.9 6.2 0.2 4.0 3 1 1 4 4 4 0 GAGA factor zf_UBZ PF18439.1 PVD27508.1 - 1.3 8.7 0.0 0.24 11.0 0.5 7.1 8 1 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD27508.1 - 1.3 9.2 0.0 1.3 9.2 0.0 5.9 4 2 1 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD27508.1 - 2.2 8.6 33.3 4.8 7.6 8.6 6.3 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.7 PVD27508.1 - 3.4 7.9 22.1 0.44 10.7 0.3 5.4 6 0 0 6 6 6 0 Zinc-binding Rpr2 PF04032.16 PVD27508.1 - 4.8 7.5 23.1 1.6 9.0 0.7 4.6 2 2 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.21 PVD27508.1 - 6.4 7.0 37.1 12 6.1 1.6 5.1 1 1 3 4 4 4 0 FYVE zinc finger Zn_ribbon_SprT PF17283.2 PVD27508.1 - 6.8 6.7 26.8 1.1 9.2 0.4 5.8 5 1 1 6 6 5 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 PVD27508.1 - 9.6 5.9 15.0 24 4.6 0.1 4.9 4 2 1 5 5 5 0 MYST family zinc finger domain zf-C2H2_4 PF13894.6 PVD27509.1 - 6.2e-16 57.7 31.3 0.0013 19.4 3.0 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD27509.1 - 2.6e-13 49.6 30.8 0.0049 17.3 0.9 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD27509.1 - 5.6e-11 42.4 14.3 0.011 16.0 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD27509.1 - 8.4e-11 41.8 43.8 0.00033 20.9 2.4 6.8 6 1 0 6 6 6 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD27509.1 - 4.4e-09 36.1 27.0 3.8e-05 23.6 2.3 5.9 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 PVD27509.1 - 0.0002 21.6 21.6 1.4 9.4 0.1 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD27509.1 - 0.00041 20.0 11.0 0.0086 15.8 0.0 3.9 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PVD27509.1 - 0.00065 20.0 14.3 0.0073 16.6 0.7 4.2 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 PVD27509.1 - 0.0047 17.6 5.6 0.0047 17.6 5.6 1.9 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 PVD27509.1 - 0.0053 17.0 12.4 0.17 12.2 6.4 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon RNA_POL_M_15KD PF02150.16 PVD27509.1 - 0.025 14.5 6.9 0.19 11.6 0.2 3.8 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zinc_ribbon_15 PF17032.5 PVD27509.1 - 0.082 13.7 6.8 0.32 11.8 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_9 PF16293.5 PVD27509.1 - 0.49 10.3 0.1 0.49 10.3 0.1 3.7 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 PVD27509.1 - 0.91 9.6 0.0 0.91 9.6 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger domain Zn-C2H2_12 PF18112.1 PVD27509.1 - 2.5 8.7 0.0 2.5 8.7 0.0 3.9 4 1 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 PVD27510.1 - 3.4e-07 30.5 5.8 0.0039 17.9 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD27510.1 - 0.00013 22.2 6.9 0.0053 17.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD27510.1 - 0.02 15.2 3.7 1.3 9.4 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 PVD27510.1 - 0.11 12.8 2.3 15 5.9 0.1 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 PVD27510.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger Ig_2 PF13895.6 PVD27511.1 - 3.5e-127 415.0 50.4 1.4e-12 47.8 0.3 14.2 13 1 1 14 14 14 14 Immunoglobulin domain Ig_3 PF13927.6 PVD27511.1 - 3.4e-124 405.7 47.6 1.3e-09 38.5 0.3 14.6 14 0 0 14 14 14 14 Immunoglobulin domain I-set PF07679.16 PVD27511.1 - 8.2e-88 288.6 18.1 3e-09 36.8 0.0 18.7 14 10 0 14 14 14 14 Immunoglobulin I-set domain ig PF00047.25 PVD27511.1 - 3.7e-62 206.5 44.7 2.2e-05 24.5 0.0 16.7 14 4 0 14 14 14 13 Immunoglobulin domain Ig_4 PF16680.5 PVD27511.1 - 4.8e-33 113.3 16.2 0.0082 16.4 0.1 12.0 12 0 0 12 12 12 8 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD27511.1 - 1.1e-28 99.4 3.6 0.00091 19.6 0.1 11.8 12 0 0 12 12 12 6 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 PVD27511.1 - 4.9e-27 94.3 58.4 0.0015 18.7 0.0 22.3 15 11 10 25 25 25 6 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD27511.1 - 4.6e-23 80.5 0.0 0.039 13.5 0.0 12.0 13 0 0 13 13 13 6 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27511.1 - 1e-18 67.2 0.4 0.7 10.0 0.0 10.8 12 0 0 12 12 12 4 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD27511.1 - 1.7e-11 44.1 1.6 1.7 8.9 0.0 8.6 10 1 0 10 10 9 3 Immunoglobulin C2-set domain fn3 PF00041.21 PVD27511.1 - 2.8e-10 40.4 0.0 8.3e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Ig_C17orf99 PF17736.1 PVD27511.1 - 0.00031 20.7 12.1 2.1 8.5 0.0 9.5 10 1 0 10 10 9 1 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 PVD27511.1 - 0.0019 18.0 0.9 20 5.0 0.0 5.9 6 0 0 6 6 6 0 Adenovirus E3 region protein CR1 C1-set PF07654.15 PVD27511.1 - 0.0046 17.3 1.9 38 4.8 0.0 5.2 4 0 0 4 4 4 0 Immunoglobulin C1-set domain ICAM_N PF03921.14 PVD27511.1 - 0.0072 16.0 44.7 0.23 11.2 0.2 10.5 12 0 0 12 12 11 3 Intercellular adhesion molecule (ICAM), N-terminal domain V-set_CD47 PF08204.11 PVD27511.1 - 0.024 14.6 7.7 17 5.4 0.1 6.6 6 1 1 7 7 7 0 CD47 immunoglobulin-like domain GPI-anchored PF10342.9 PVD27511.1 - 0.18 12.6 3.2 0.67 10.8 0.1 3.7 4 1 0 4 4 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ig_3 PF13927.6 PVD27512.1 - 5.5e-31 107.0 11.5 1.8e-11 44.4 1.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27512.1 - 2.5e-28 98.2 9.7 8.8e-10 38.8 0.8 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD27512.1 - 1.1e-23 83.1 4.4 1.1e-06 28.6 0.2 5.1 3 3 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD27512.1 - 3.9e-20 71.8 10.4 1.4e-06 28.4 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 PVD27512.1 - 1.3e-12 47.7 5.5 0.0002 21.6 0.2 3.2 3 0 0 3 3 3 3 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 PVD27512.1 - 3.3e-11 43.3 14.7 0.042 14.0 0.1 5.5 3 3 3 6 6 6 4 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD27512.1 - 5.5e-11 42.7 1.6 0.0051 17.2 0.2 3.2 3 0 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD27512.1 - 8e-06 25.3 0.0 0.15 11.7 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27512.1 - 3.1e-05 23.9 0.2 5.7 7.1 0.0 3.4 3 0 0 3 3 3 3 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD27512.1 - 0.0036 17.1 0.2 3.3 7.6 0.0 3.0 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 UL141 PF16758.5 PVD27512.1 - 0.0044 16.8 0.5 1.2 8.8 0.0 2.7 3 1 0 3 3 3 1 Herpes-like virus membrane glycoprotein UL141 Pilin PF00114.19 PVD27512.1 - 0.0075 17.2 7.1 3.4 8.6 0.6 3.5 2 1 1 3 3 3 1 Pilin (bacterial filament) ICAM_N PF03921.14 PVD27512.1 - 0.012 15.2 5.1 0.95 9.2 0.2 3.4 3 0 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain Invasin_D3 PF09134.10 PVD27512.1 - 0.022 15.0 1.7 14 6.0 0.1 3.3 3 0 0 3 3 3 0 Invasin, domain 3 Ig_2 PF13895.6 PVD27513.1 - 2e-22 79.3 11.1 5.1e-11 42.7 1.4 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 PVD27513.1 - 2.6e-19 69.6 11.2 7.4e-08 32.9 1.1 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD27513.1 - 4.6e-19 68.3 4.1 1.7e-05 24.8 0.3 4.9 2 2 1 3 3 3 3 Immunoglobulin I-set domain Ig_4 PF16680.5 PVD27513.1 - 1.6e-10 41.0 3.2 0.004 17.4 0.7 3.2 2 1 1 3 3 3 3 T-cell surface glycoprotein CD3 delta chain ig PF00047.25 PVD27513.1 - 2e-10 40.7 12.2 0.013 15.6 0.2 4.3 2 2 1 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 PVD27513.1 - 1.1e-08 34.5 0.0 0.27 10.8 0.0 3.6 2 2 1 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 PVD27513.1 - 1.7e-07 31.6 0.5 0.023 15.1 0.1 3.1 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 PVD27513.1 - 0.00023 21.3 9.1 0.026 14.7 1.1 4.3 2 2 1 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD27513.1 - 0.0047 17.0 0.1 8.5 6.5 0.0 3.3 2 1 1 3 3 3 1 Izumo-like Immunoglobulin domain Pilin PF00114.19 PVD27513.1 - 0.069 14.1 3.6 7.5 7.5 0.1 2.5 2 1 1 3 3 3 0 Pilin (bacterial filament) C2-set_2 PF08205.12 PVD27513.1 - 0.085 12.9 3.1 4.2 7.5 0.1 3.0 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain zf-CCCH PF00642.24 PVD27514.1 - 2e-13 49.9 16.5 1.7e-06 27.8 6.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 PVD27514.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PVD27514.1 - 5e-05 23.9 8.2 0.021 15.5 0.2 2.8 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 PVD27514.1 - 8.5e-05 22.5 14.0 0.032 14.3 2.6 2.5 2 0 0 2 2 2 2 Zinc finger domain PRP38_assoc PF12871.7 PVD27514.1 - 0.0055 17.3 32.9 0.01 16.4 32.9 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nup35_RRM_2 PF14605.6 PVD27514.1 - 0.021 14.8 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 PVD27514.1 - 0.1 12.8 4.1 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family GRP PF07172.11 PVD27514.1 - 0.31 11.8 18.9 0.56 10.9 18.9 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF445 PF04286.12 PVD27516.1 - 0.081 12.7 7.9 0.15 11.8 2.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF3827 PF12877.7 PVD27517.1 - 0.00016 20.2 0.0 0.00018 20.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) CitMHS PF03600.16 PVD27517.1 - 0.0021 17.3 0.0 0.0021 17.3 0.0 1.1 1 0 0 1 1 1 1 Citrate transporter Adeno_E3_CR2 PF02439.15 PVD27517.1 - 0.018 14.8 5.0 0.034 13.9 5.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PVD27517.1 - 0.023 15.6 0.0 0.037 14.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD27517.1 - 0.046 13.6 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 PVD27517.1 - 0.08 12.9 3.5 0.077 13.0 1.5 1.8 1 1 1 2 2 2 0 Protocadherin Collectrin PF16959.5 PVD27517.1 - 0.096 12.4 1.0 0.18 11.6 1.0 1.4 1 0 0 1 1 1 0 Renal amino acid transporter SdpI PF13630.6 PVD27517.1 - 0.63 10.2 9.2 3.2 7.9 1.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2970 PF11174.8 PVD27517.1 - 2.6 8.0 10.3 0.66 9.9 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) TPPK_C PF12555.8 PVD27517.1 - 3.8 7.6 9.6 0.75 9.9 4.4 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal EphA2_TM PF14575.6 PVD27518.1 - 9e-09 36.1 0.0 0.0047 17.8 0.0 2.8 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 PVD27518.1 - 1.6e-06 27.9 2.7 0.006 16.2 0.3 2.3 2 0 0 2 2 2 2 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 PVD27518.1 - 5.2e-06 26.4 2.1 0.039 13.9 0.4 2.5 2 0 0 2 2 2 2 TMEM154 protein family Amnionless PF14828.6 PVD27518.1 - 2.7e-05 23.2 0.0 0.083 11.7 0.0 2.2 2 0 0 2 2 2 2 Amnionless DUF3852 PF12963.7 PVD27518.1 - 0.0001 22.6 8.0 0.0058 16.9 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3852) RTX PF02382.15 PVD27518.1 - 0.00026 20.8 4.5 0.038 13.7 0.6 2.2 2 0 0 2 2 2 2 N-terminal domain in RTX protein Protocadherin PF08374.11 PVD27518.1 - 0.00027 21.0 5.8 0.11 12.4 0.7 2.3 2 0 0 2 2 2 2 Protocadherin DUF4446 PF14584.6 PVD27518.1 - 0.00055 19.9 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) Cadherin_C_2 PF16492.5 PVD27518.1 - 0.00058 20.6 0.3 2.8 8.8 0.0 3.3 4 0 0 4 4 2 1 Cadherin cytoplasmic C-terminal DUF4381 PF14316.6 PVD27518.1 - 0.00074 19.8 0.0 0.86 9.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Myc_target_1 PF15179.6 PVD27518.1 - 0.0012 18.8 0.3 2 8.3 0.0 2.6 2 0 0 2 2 2 2 Myc target protein 1 Phage_holin_3_6 PF07332.11 PVD27518.1 - 0.002 18.1 3.3 0.81 9.7 0.4 2.2 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III MscL PF01741.18 PVD27518.1 - 0.0021 18.3 1.0 1.3 9.3 0.1 2.3 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL DUF1180 PF06679.12 PVD27518.1 - 0.0031 18.0 4.1 0.71 10.3 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) SBD PF17882.1 PVD27518.1 - 0.0031 17.3 1.1 4.8 7.0 0.0 3.1 3 0 0 3 3 3 0 OAA-family lectin sugar binding domain OSTbeta PF15048.6 PVD27518.1 - 0.0034 17.5 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein DUF5305 PF17231.2 PVD27518.1 - 0.0058 16.0 2.7 1 8.7 0.4 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5305) DUF973 PF06157.11 PVD27518.1 - 0.0098 15.0 6.4 0.51 9.3 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF973) LapA_dom PF06305.11 PVD27518.1 - 0.011 15.5 1.2 1.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4328 PF14219.6 PVD27518.1 - 0.012 15.2 0.2 6.9 6.2 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4328) SCIMP PF15050.6 PVD27518.1 - 0.014 15.8 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 SCIMP protein Edc3_linker PF16598.5 PVD27518.1 - 0.014 16.0 4.6 2.1 9.1 0.3 2.5 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Izumo-Ig PF16706.5 PVD27518.1 - 0.017 15.2 0.0 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain STE3 PF02076.15 PVD27518.1 - 0.021 14.0 0.7 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Pheromone A receptor DUF697 PF05128.12 PVD27518.1 - 0.024 14.4 2.9 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) DUF1918 PF08940.11 PVD27518.1 - 0.036 13.7 0.0 18 5.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) MtrC PF04211.13 PVD27518.1 - 0.036 13.1 16.8 0.14 11.1 3.2 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C CcmD PF04995.14 PVD27518.1 - 0.039 14.0 5.5 1.9 8.6 1.1 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3169 PF11368.8 PVD27518.1 - 0.052 13.1 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) C2-set_2 PF08205.12 PVD27518.1 - 0.053 13.6 18.9 10 6.2 0.5 5.7 3 3 2 5 5 5 0 CD80-like C2-set immunoglobulin domain RIFIN PF02009.16 PVD27518.1 - 0.054 13.4 8.5 0.22 11.4 0.1 2.4 2 1 0 2 2 2 0 Rifin Syndecan PF01034.20 PVD27518.1 - 0.063 13.2 6.6 1 9.3 0.1 2.6 2 0 0 2 2 2 0 Syndecan domain TDRP PF15683.5 PVD27518.1 - 0.07 13.1 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Testis development-related protein MotA_ExbB PF01618.16 PVD27518.1 - 0.075 12.8 3.6 0.3 10.9 0.4 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF4692 PF15763.5 PVD27518.1 - 0.085 13.3 0.0 26 5.3 0.0 2.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF2207 PF09972.9 PVD27518.1 - 0.097 11.4 0.1 8.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glycolipid_bind PF06475.11 PVD27518.1 - 0.1 12.1 2.1 3.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Putative glycolipid-binding Zip PF02535.22 PVD27518.1 - 0.1 11.8 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter Baculo_11_kDa PF06143.11 PVD27518.1 - 0.16 11.6 3.7 5.8 6.6 0.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family SseC PF04888.12 PVD27518.1 - 0.19 11.3 3.6 5.3 6.5 0.2 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ig PF00047.25 PVD27518.1 - 0.21 11.8 19.9 7.4 6.8 0.4 5.3 3 2 2 5 5 5 0 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 PVD27518.1 - 0.44 10.3 14.1 1 9.2 3.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2755 PF10954.8 PVD27518.1 - 0.8 9.7 6.7 9.1 6.3 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF1043 PF06295.12 PVD27518.1 - 1.5 8.9 2.8 37 4.3 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF2270 PF10028.9 PVD27518.1 - 9.1 5.8 8.1 6.1 6.4 1.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2270) DUF4166 PF13761.6 PVD27519.1 - 0.02 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) ig PF00047.25 PVD27519.1 - 0.11 12.6 15.2 2.5 8.3 1.5 4.1 3 2 1 4 4 4 0 Immunoglobulin domain C2-set_2 PF08205.12 PVD27519.1 - 0.27 11.3 8.6 5.4 7.2 0.5 3.9 3 2 1 4 4 4 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27521.1 - 0.019 15.6 14.0 0.39 11.4 1.8 3.3 3 1 0 3 3 3 0 Immunoglobulin domain ig PF00047.25 PVD27521.1 - 0.089 13.0 12.2 0.83 9.9 2.1 3.3 2 1 1 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.12 PVD27521.1 - 0.15 12.2 9.8 4.9 7.3 0.0 3.7 2 2 2 4 4 4 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27522.1 - 0.00071 20.1 9.8 0.27 11.9 0.8 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD27522.1 - 0.005 17.0 11.7 1.8 8.8 3.7 3.7 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD27522.1 - 0.062 13.4 9.4 2.8 8.1 0.1 3.9 2 2 1 3 3 3 0 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27523.1 - 0.007 16.5 0.8 6.1 7.1 0.2 3.3 2 2 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 PVD27523.1 - 0.045 14.4 2.9 0.92 10.2 1.2 2.7 2 0 0 2 2 2 0 Immunoglobulin domain DUF3421 PF11901.8 PVD27523.1 - 0.093 12.7 0.0 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) Stevor PF17410.2 PVD27524.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PVD27524.1 - 0.024 15.5 0.2 0.051 14.5 0.2 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 PVD27524.1 - 0.15 12.7 5.6 0.48 11.0 2.4 2.8 2 1 0 2 2 2 0 Immunoglobulin domain RTX PF02382.15 PVD27524.1 - 0.27 10.9 1.3 0.36 10.5 1.3 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein ig PF00047.25 PVD27524.1 - 0.39 10.9 4.3 7.9 6.7 3.1 2.6 1 1 1 2 2 2 0 Immunoglobulin domain Lectin_C PF00059.21 PVD27525.1 - 7e-10 39.6 1.6 1.6e-08 35.3 0.3 2.2 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 PVD27525.1 - 0.00095 18.9 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27526.1 - 5e-17 62.6 0.4 6.6e-17 62.2 0.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD27527.1 - 8.5e-14 52.2 0.1 1.1e-13 51.9 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27527.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like FLYWCH PF04500.16 PVD27528.1 - 2.2e-09 37.3 0.5 2.2e-09 37.3 0.5 3.1 2 0 0 2 2 2 1 FLYWCH zinc finger domain SBD PF17882.1 PVD27528.1 - 8.5e-06 25.6 3.1 0.24 11.2 0.4 4.2 3 1 0 3 3 3 2 OAA-family lectin sugar binding domain SKG6 PF08693.10 PVD27528.1 - 0.00011 21.6 5.8 0.00022 20.6 5.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1918 PF08940.11 PVD27528.1 - 0.00033 20.2 0.0 15 5.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) DUF4944 PF16302.5 PVD27528.1 - 0.00061 19.8 0.3 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4944) Phage_holin_3_6 PF07332.11 PVD27528.1 - 0.0045 17.0 0.2 0.0075 16.3 0.2 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III C2-set_2 PF08205.12 PVD27528.1 - 0.0048 16.9 31.9 5.4 7.1 3.4 7.3 5 4 0 5 5 5 3 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.6 PVD27528.1 - 0.012 15.6 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family Glycolipid_bind PF06475.11 PVD27528.1 - 0.015 14.8 5.5 6.8 6.2 0.2 3.4 3 0 0 3 3 3 0 Putative glycolipid-binding TolB_N PF04052.13 PVD27528.1 - 0.036 14.2 0.0 83 3.4 0.0 3.2 3 0 0 3 3 3 0 TolB amino-terminal domain Stevor PF17410.2 PVD27528.1 - 0.037 13.6 0.2 0.067 12.7 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame dsrm PF00035.26 PVD27528.1 - 0.047 14.4 2.3 71 4.2 0.1 3.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif EphA2_TM PF14575.6 PVD27528.1 - 0.087 13.7 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DNA_pol_B_N PF18094.1 PVD27528.1 - 0.21 12.2 2.7 12 6.5 0.0 4.0 4 2 0 4 4 3 0 DNA polymerase beta N-terminal domain DUF4333 PF14230.6 PVD27528.1 - 0.38 11.0 17.4 25 5.2 0.0 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4333) cpYpsA PF12694.7 PVD27528.1 - 1.1 9.0 4.3 6.5 6.5 0.2 3.1 2 1 1 3 3 3 0 Circularly permutated YpsA SLOG family Stevor PF17410.2 PVD27529.1 - 0.0088 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PVD27529.1 - 0.0097 16.8 0.0 0.028 15.3 0.0 1.9 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TrbM PF07424.11 PVD27529.1 - 0.014 15.3 2.4 2.6 8.0 0.1 2.7 2 1 0 2 2 2 0 TrbM TMEM154 PF15102.6 PVD27529.1 - 0.046 13.6 0.1 0.097 12.6 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 PVD27529.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Rifin Stevor PF17410.2 PVD27530.1 - 0.0015 18.1 0.3 0.0027 17.3 0.3 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PVD27530.1 - 0.0018 19.1 0.1 0.004 18.0 0.0 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 PVD27530.1 - 0.0053 16.7 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 PVD27530.1 - 0.007 16.3 1.0 0.016 15.1 1.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family DUF456 PF04306.13 PVD27530.1 - 0.016 15.5 0.2 0.028 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Adeno_E3_CR2 PF02439.15 PVD27530.1 - 0.025 14.3 1.3 0.042 13.6 1.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 PVD27530.1 - 0.046 12.5 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 PVD27530.1 - 0.05 13.5 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 PVD27530.1 - 0.054 12.9 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PGF-CTERM PF18204.1 PVD27530.1 - 0.32 11.0 3.3 0.67 10.0 3.3 1.6 1 0 0 1 1 1 0 PGF-CTERM motif ig PF00047.25 PVD27530.1 - 0.38 11.0 11.9 13 6.0 1.0 3.8 3 1 0 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.12 PVD27530.1 - 3.3 7.9 11.0 5.4 7.2 0.5 3.9 3 2 2 5 5 5 0 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.6 PVD27531.1 - 0.0091 16.9 0.3 0.014 16.2 0.3 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PhoR PF11808.8 PVD27531.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR MHYT PF03707.16 PVD27531.1 - 0.036 14.2 0.6 0.057 13.6 0.6 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat MACPF PF01823.19 PVD27532.1 - 4.4e-39 134.7 0.2 5.7e-19 69.0 0.0 2.6 3 0 0 3 3 3 2 MAC/Perforin domain Fibrinogen_C PF00147.18 PVD27532.1 - 1.1e-09 38.5 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_3 PF08277.12 PVD27532.1 - 4.8e-08 32.7 24.2 0.013 15.3 1.2 4.8 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 PVD27532.1 - 8.8e-08 32.2 20.9 0.00047 20.2 0.6 4.5 4 0 0 4 4 4 2 PAN-like domain PAN_4 PF14295.6 PVD27532.1 - 8.6e-07 28.8 23.8 0.048 13.6 0.4 4.8 4 0 0 4 4 4 4 PAN domain DUF3878 PF12994.7 PVD27532.1 - 0.015 14.8 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3878) CSG2 PF16965.5 PVD27532.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Aida_N PF08910.10 PVD27532.1 - 0.067 13.6 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 Aida N-terminus Borrelia_P83 PF05262.11 PVD27532.1 - 0.35 9.3 4.9 0.61 8.5 4.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 PVD27532.1 - 9.6 4.4 19.0 15 3.7 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein MACPF PF01823.19 PVD27533.1 - 1.1e-19 71.4 0.0 1.9e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 MAC/Perforin domain PAN_4 PF14295.6 PVD27533.1 - 0.0001 22.1 6.8 0.026 14.4 0.2 2.9 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 PVD27533.1 - 0.0001 22.0 7.9 0.0087 15.8 0.9 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.11 PVD27533.1 - 0.0024 18.0 0.3 0.0024 18.0 0.3 3.0 3 0 0 3 3 3 2 PAN-like domain EB PF01683.18 PVD27533.1 - 0.013 15.7 8.8 0.013 15.7 8.8 2.7 2 1 0 2 2 2 0 EB module Fibrinogen_C PF00147.18 PVD27534.1 - 4.7e-10 39.6 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_4 PF14295.6 PVD27534.1 - 2.1e-07 30.8 10.3 0.002 18.0 0.5 2.8 2 0 0 2 2 2 2 PAN domain EB PF01683.18 PVD27534.1 - 0.00037 20.7 1.6 0.00037 20.7 1.6 3.3 3 1 0 3 3 3 1 EB module PAN_3 PF08277.12 PVD27534.1 - 0.0042 16.9 22.7 0.033 14.0 0.9 3.4 3 1 0 3 3 3 2 PAN-like domain PAN_2 PF08276.11 PVD27534.1 - 0.012 15.7 0.4 0.012 15.7 0.4 3.3 3 0 0 3 3 3 0 PAN-like domain MANEC PF07502.14 PVD27534.1 - 0.28 11.5 15.0 2.8 8.3 1.2 2.8 1 1 1 2 2 2 0 MANEC domain MACPF PF01823.19 PVD27535.1 - 1.4e-34 120.0 0.0 2.4e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 MAC/Perforin domain PAN_4 PF14295.6 PVD27535.1 - 0.00032 20.5 9.3 0.019 14.9 0.3 2.7 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27535.1 - 0.00035 20.6 8.1 0.00067 19.7 0.1 2.8 2 0 0 2 2 2 1 PAN-like domain PAN_3 PF08277.12 PVD27535.1 - 0.0047 16.7 14.2 0.13 12.1 0.7 3.5 3 0 0 3 3 3 2 PAN-like domain Fibrinogen_C PF00147.18 PVD27536.1 - 7.8e-11 42.2 0.0 2e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_4 PF14295.6 PVD27536.1 - 6.6e-07 29.1 10.6 0.0033 17.3 0.7 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 PVD27536.1 - 1.2e-06 28.4 17.3 0.00077 19.4 2.8 2.9 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 PVD27536.1 - 0.0027 17.8 7.1 0.021 14.9 0.4 2.7 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.12 PVD27536.1 - 0.0056 16.5 18.2 0.066 13.0 1.1 3.2 3 1 0 3 3 3 2 PAN-like domain EB PF01683.18 PVD27536.1 - 6.2 7.2 21.8 0.026 14.8 8.3 3.1 3 1 0 3 3 3 0 EB module MACPF PF01823.19 PVD27537.1 - 1.8e-21 77.2 0.0 3.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain PAN_1 PF00024.26 PVD27537.1 - 7.6e-10 38.6 21.5 0.00022 21.1 1.0 3.9 4 0 0 4 4 4 3 PAN domain PAN_4 PF14295.6 PVD27537.1 - 0.00011 22.0 22.9 0.023 14.6 3.2 4.0 4 0 0 4 4 4 3 PAN domain EB PF01683.18 PVD27537.1 - 0.00041 20.6 0.7 0.00041 20.6 0.7 3.1 3 0 0 3 3 3 1 EB module PAN_2 PF08276.11 PVD27537.1 - 0.0023 18.0 13.1 0.058 13.5 0.3 3.7 3 0 0 3 3 3 2 PAN-like domain PAN_3 PF08277.12 PVD27537.1 - 0.0051 16.6 22.3 0.011 15.5 1.1 4.0 4 0 0 4 4 4 2 PAN-like domain MACPF PF01823.19 PVD27538.1 - 3.7e-18 66.4 0.0 6.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain PAN_3 PF08277.12 PVD27538.1 - 2.9e-06 27.0 7.9 0.0048 16.7 1.0 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_1 PF00024.26 PVD27538.1 - 0.0002 21.3 17.5 0.02 14.9 6.6 2.4 1 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PVD27538.1 - 0.00057 19.7 9.5 0.056 13.3 0.3 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27538.1 - 0.0086 16.2 1.1 0.0086 16.2 1.1 3.1 2 1 1 3 3 3 1 PAN-like domain MACPF PF01823.19 PVD27539.1 - 4.7e-24 85.7 0.2 2.2e-18 67.2 0.0 2.9 3 0 0 3 3 3 2 MAC/Perforin domain PAN_3 PF08277.12 PVD27539.1 - 0.0002 21.1 7.5 0.013 15.3 1.0 2.7 2 0 0 2 2 2 2 PAN-like domain EB PF01683.18 PVD27539.1 - 0.00026 21.2 1.1 0.00026 21.2 1.1 3.0 3 0 0 3 3 3 1 EB module PAN_4 PF14295.6 PVD27539.1 - 0.00036 20.4 7.6 0.072 13.0 0.3 2.8 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27539.1 - 0.011 15.8 0.1 0.011 15.8 0.1 3.2 3 0 0 3 3 3 0 PAN-like domain DUF2828 PF11443.8 PVD27539.1 - 1.7 6.6 8.9 1.9 6.4 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) MACPF PF01823.19 PVD27540.1 - 4e-18 66.3 0.0 1.1e-17 64.9 0.0 1.6 1 1 0 1 1 1 1 MAC/Perforin domain PAN_3 PF08277.12 PVD27540.1 - 2e-05 24.3 7.2 0.0085 15.9 0.9 2.8 2 0 0 2 2 2 2 PAN-like domain EB PF01683.18 PVD27540.1 - 0.00011 22.4 1.4 0.00011 22.4 1.4 3.1 3 0 0 3 3 3 1 EB module PAN_4 PF14295.6 PVD27540.1 - 0.00015 21.6 8.0 0.014 15.3 0.4 2.9 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27540.1 - 0.00017 21.6 0.2 0.00017 21.6 0.2 3.1 3 0 0 3 3 3 2 PAN-like domain MACPF PF01823.19 PVD27541.1 - 4.4e-19 69.4 0.0 1.2e-18 68.0 0.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain PAN_3 PF08277.12 PVD27541.1 - 0.0024 17.6 10.3 0.3 10.9 0.6 3.0 2 1 0 2 2 2 2 PAN-like domain EB PF01683.18 PVD27541.1 - 0.0036 17.5 9.7 0.0036 17.5 9.7 2.8 2 1 0 2 2 2 1 EB module PAN_4 PF14295.6 PVD27541.1 - 0.0051 16.7 8.4 0.68 9.9 2.4 2.8 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27541.1 - 0.0079 16.3 0.2 0.0079 16.3 0.2 2.7 3 0 0 3 3 3 1 PAN-like domain DUF2828 PF11443.8 PVD27541.1 - 5.9 4.8 8.1 10 4.1 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Fibrinogen_C PF00147.18 PVD27542.1 - 1.3e-11 44.7 0.0 1.5e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MACPF PF01823.19 PVD27543.1 - 1.9e-17 64.1 0.0 3.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain PAN_1 PF00024.26 PVD27543.1 - 0.0099 15.8 5.1 0.4 10.7 0.2 3.1 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27543.1 - 0.01 15.9 0.2 0.01 15.9 0.2 3.3 3 0 0 3 3 3 0 PAN-like domain PAN_3 PF08277.12 PVD27543.1 - 0.019 14.7 13.1 0.38 10.6 0.6 3.3 3 1 0 3 3 3 0 PAN-like domain PAN_4 PF14295.6 PVD27543.1 - 0.1 12.5 12.9 1.1 9.2 2.7 3.3 3 0 0 3 3 3 0 PAN domain PDGF PF00341.17 PVD27543.1 - 0.89 9.9 6.6 0.3 11.4 1.3 2.8 3 0 0 3 3 3 0 PDGF/VEGF domain DUF2457 PF10446.9 PVD27544.1 - 0.1 11.7 11.4 0.16 11.0 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 PVD27544.1 - 0.15 10.2 1.2 0.24 9.5 1.2 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 PVD27544.1 - 0.45 9.0 3.1 0.81 8.2 3.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 PVD27544.1 - 0.47 8.5 7.8 0.63 8.1 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 PVD27544.1 - 0.49 10.8 16.3 1.4 9.4 16.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Utp14 PF04615.13 PVD27544.1 - 0.74 8.3 2.4 1.2 7.6 2.4 1.2 1 0 0 1 1 1 0 Utp14 protein Cwf_Cwc_15 PF04889.12 PVD27544.1 - 1.3 8.7 15.0 0.085 12.6 10.0 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ANAPC9 PF12856.7 PVD27544.1 - 2 8.6 6.0 27 5.0 2.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 Sigma70_ner PF04546.13 PVD27544.1 - 2.5 7.9 5.3 0.37 10.6 1.3 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Spt5_N PF11942.8 PVD27544.1 - 3.1 8.9 13.6 0.89 10.6 10.5 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SKG6 PF08693.10 PVD27545.1 - 0.41 10.1 3.4 0.83 9.1 3.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EB PF01683.18 PVD27546.1 - 8.4e-06 26.0 10.8 1.1e-05 25.7 8.7 2.2 1 1 1 2 2 2 1 EB module Fibrinogen_C PF00147.18 PVD27546.1 - 7.9e-05 22.6 0.2 0.00012 21.9 0.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 PVD27546.1 - 0.0013 19.1 6.7 0.0013 19.1 6.7 2.6 3 0 0 3 3 3 1 EGF-like domain Toxin_23 PF08093.11 PVD27546.1 - 0.028 14.6 8.1 0.032 14.4 4.7 2.7 2 0 0 2 2 2 0 Magi 5 toxic peptide family PAN_1 PF00024.26 PVD27546.1 - 0.95 9.5 10.4 3.4 7.7 10.3 2.1 1 1 0 1 1 1 0 PAN domain PAN_2 PF08276.11 PVD27547.1 - 0.00017 21.6 0.6 0.00017 21.6 0.6 2.6 3 0 0 3 3 3 1 PAN-like domain PAN_3 PF08277.12 PVD27547.1 - 0.0013 18.5 13.1 0.17 11.7 4.9 3.0 2 1 0 2 2 2 2 PAN-like domain GcnA_N PF18229.1 PVD27547.1 - 0.24 11.5 0.9 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain PAN_4 PF14295.6 PVD27547.1 - 0.46 10.4 6.2 0.81 9.6 0.4 2.8 2 0 0 2 2 2 0 PAN domain MACPF PF01823.19 PVD27548.1 - 1e-21 78.0 0.0 1.6e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain EB PF01683.18 PVD27548.1 - 8e-05 22.8 1.2 8e-05 22.8 1.2 2.9 3 0 0 3 3 3 1 EB module PAN_3 PF08277.12 PVD27548.1 - 9.2e-05 22.2 7.1 0.0084 15.9 1.1 2.9 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.6 PVD27548.1 - 0.00083 19.2 8.2 0.048 13.6 0.2 2.9 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27548.1 - 0.0024 17.9 0.2 0.0024 17.9 0.2 3.0 3 0 0 3 3 3 1 PAN-like domain MACPF PF01823.19 PVD27549.1 - 1.1e-24 87.7 0.8 2.9e-24 86.3 0.8 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Hyd_WA PF06462.12 PVD27550.1 - 2.3e-12 46.7 4.7 0.00012 22.0 0.2 4.1 4 0 0 4 4 4 3 Propeller MACPF PF01823.19 PVD27551.1 - 4.1e-25 89.1 1.3 8.5e-25 88.1 1.3 1.5 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 PVD27552.1 - 1.9e-23 83.7 2.9 4.1e-23 82.6 2.9 1.6 1 0 0 1 1 1 1 MAC/Perforin domain Hyd_WA PF06462.12 PVD27553.1 - 1.6e-09 37.5 9.0 0.00034 20.5 0.1 4.1 4 0 0 4 4 4 2 Propeller CARDB PF07705.11 PVD27554.1 - 0.059 13.6 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 CARDB Hyd_WA PF06462.12 PVD27555.1 - 4.1e-10 39.5 7.1 0.00025 21.0 0.2 4.0 4 0 0 4 4 4 2 Propeller Jiraiya PF15038.6 PVD27555.1 - 0.23 10.9 1.8 0.35 10.3 1.8 1.2 1 0 0 1 1 1 0 Jiraiya Ig_3 PF13927.6 PVD27556.1 - 1.8e-18 66.9 26.7 4e-05 24.1 0.2 7.6 8 0 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 PVD27556.1 - 8.5e-14 51.7 23.0 0.0036 17.6 0.1 7.4 7 1 0 7 7 7 4 Immunoglobulin domain PT PF04886.12 PVD27556.1 - 4e-12 45.5 30.2 1.5e-11 43.6 30.2 2.1 1 0 0 1 1 1 1 PT repeat I-set PF07679.16 PVD27556.1 - 2.3e-09 37.2 1.2 0.74 9.9 0.0 7.2 7 1 0 7 7 7 2 Immunoglobulin I-set domain V-set PF07686.17 PVD27556.1 - 4.8e-05 23.5 8.9 0.29 11.3 0.1 6.9 6 1 0 6 6 6 2 Immunoglobulin V-set domain CABIT PF12736.7 PVD27556.1 - 0.0037 16.6 0.0 0.011 15.0 0.0 1.8 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, ig PF00047.25 PVD27556.1 - 0.0087 16.2 18.8 1.1 9.4 0.1 6.1 6 0 0 6 6 6 2 Immunoglobulin domain PCC_BT PF18140.1 PVD27556.1 - 0.096 13.0 0.5 5.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain Ig_4 PF16680.5 PVD27556.1 - 0.12 12.6 0.7 33 4.8 0.0 3.8 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain DUF4106 PF13388.6 PVD27556.1 - 0.45 9.7 8.4 0.76 8.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) 7tm_1 PF00001.21 PVD27557.1 - 3.5e-15 56.1 21.7 5.1e-15 55.5 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MACPF PF01823.19 PVD27558.1 - 5.2e-16 59.4 0.0 7.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain PAN_2 PF08276.11 PVD27558.1 - 4.6e-06 26.6 7.1 2.7e-05 24.2 0.3 2.7 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.12 PVD27558.1 - 7.5e-06 25.7 8.1 0.0074 16.1 0.9 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.6 PVD27558.1 - 0.00016 21.5 8.7 0.01 15.7 0.6 2.8 2 0 0 2 2 2 2 PAN domain Ig_3 PF13927.6 PVD27559.1 - 4.7e-07 30.3 5.8 1.9e-05 25.2 1.4 3.8 3 1 1 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27559.1 - 0.00014 22.1 3.0 0.00052 20.3 1.4 2.5 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD27559.1 - 0.00025 21.2 1.1 0.00025 21.2 1.1 3.0 4 0 0 4 4 4 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27559.1 - 0.0022 18.0 0.5 0.0095 16.0 0.2 2.1 2 0 0 2 2 2 1 C17orf99 Ig domain DUF5383 PF17355.2 PVD27559.1 - 0.014 15.8 0.0 0.042 14.2 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) C2-set_2 PF08205.12 PVD27559.1 - 0.018 15.1 1.2 1.3 9.1 0.9 3.2 2 1 1 3 3 3 0 CD80-like C2-set immunoglobulin domain DUF5344 PF17279.2 PVD27561.1 - 0.0051 17.3 0.7 24 5.6 0.0 4.1 3 1 1 4 4 4 1 Family of unknown function (DUF5344) DUF761 PF05553.11 PVD27561.1 - 0.013 15.0 0.6 0.39 10.3 0.0 3.0 2 0 0 2 2 2 0 Cotton fibre expressed protein REJ PF02010.15 PVD27562.1 - 0.013 14.3 0.0 1 8.1 0.0 2.5 1 1 1 2 2 2 0 REJ domain cEGF PF12662.7 PVD27562.1 - 0.021 14.8 3.0 0.12 12.4 0.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like PKD_channel PF08016.12 PVD27563.1 - 2.2e-72 244.1 1.9 2.2e-72 244.1 1.9 1.8 2 0 0 2 2 2 1 Polycystin cation channel GPS PF01825.21 PVD27563.1 - 4.4e-07 30.3 5.3 2.2e-06 28.1 5.3 2.3 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif AATase PF07247.12 PVD27563.1 - 0.018 13.6 0.2 0.03 12.9 0.2 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase PLAT PF01477.23 PVD27563.1 - 0.035 14.7 0.1 0.12 12.9 0.1 2.0 1 0 0 1 1 1 0 PLAT/LH2 domain DUF2207 PF09972.9 PVD27563.1 - 3.7 6.2 10.2 3.6 6.2 0.1 3.0 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) FGGY_N PF00370.21 PVD27564.1 - 5.7e-69 232.4 0.0 8.3e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PVD27564.1 - 3e-67 226.2 1.1 5.3e-67 225.4 1.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pilosulin PF17499.2 PVD27564.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Ant venom peptides Ldl_recept_b PF00058.17 PVD27565.1 - 5.5e-19 68.4 13.4 3.1e-06 27.6 0.0 9.6 10 0 0 10 10 10 4 Low-density lipoprotein receptor repeat class B Sushi PF00084.20 PVD27565.1 - 0.032 14.8 0.4 0.032 14.8 0.4 2.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) PH_6 PF15406.6 PVD27565.1 - 0.18 12.1 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Ank_2 PF12796.7 PVD27566.1 - 2.9e-44 149.5 3.1 5.4e-16 59.0 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27566.1 - 6.5e-28 95.9 1.9 1.4e-07 31.6 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 PVD27566.1 - 1.2e-21 74.4 0.5 0.00016 21.9 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PVD27566.1 - 2.3e-20 72.7 0.7 4.9e-07 30.2 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD27566.1 - 1e-15 57.5 0.6 2.3e-07 30.9 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 PVD27566.1 - 3.8e-13 49.6 0.3 9.3e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD27566.1 - 7.5e-11 42.0 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Exonuc_VII_L PF02601.15 PVD27566.1 - 2.3 7.7 5.6 3.6 7.1 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 PVD27566.1 - 7.4 6.8 8.5 14 5.9 8.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Ig_3 PF13927.6 PVD27567.1 - 6.2e-50 167.7 6.9 3.8e-12 46.6 0.1 5.2 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD27567.1 - 1.3e-46 156.5 0.0 1.2e-11 44.5 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27567.1 - 5.2e-38 129.2 0.3 2.1e-09 37.6 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 PVD27567.1 - 3.9e-28 97.5 0.0 6.3e-08 32.7 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 PVD27567.1 - 7.9e-19 67.8 0.8 1e-09 38.6 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 PVD27567.1 - 2.4e-17 63.1 0.5 0.00037 20.6 0.0 6.5 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD27567.1 - 8.1e-08 31.7 0.0 0.4 10.3 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27567.1 - 7.2e-07 29.2 0.0 0.15 12.1 0.0 3.9 4 1 1 5 5 5 2 C17orf99 Ig domain Ig_4 PF16680.5 PVD27567.1 - 8.2e-07 29.2 0.0 0.16 12.2 0.0 4.3 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD27567.1 - 0.0071 16.4 0.1 2.6 8.2 0.0 3.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.13 PVD27567.1 - 0.018 15.0 0.4 2.8 8.0 0.0 2.8 3 0 0 3 3 3 0 Y_Y_Y domain V-set PF07686.17 PVD27569.1 - 0.00083 19.5 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD27569.1 - 0.025 15.2 0.1 0.045 14.4 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 PVD27569.1 - 0.087 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain Strabismus PF06638.11 PVD27574.1 - 3.5e-198 659.4 3.5 9.2e-168 559.0 1.0 2.1 1 1 1 2 2 2 2 Strabismus protein CDT1_C PF16679.5 PVD27574.1 - 0.11 13.0 0.5 0.26 11.7 0.5 1.7 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain MtN3_slv PF03083.16 PVD27574.1 - 0.26 11.4 3.8 0.55 10.3 3.8 1.5 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF2207 PF09972.9 PVD27574.1 - 4.8 5.8 5.8 2.3 6.9 3.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DIX PF00778.17 PVD27575.1 - 7.7e-22 76.9 0.0 1.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 DIX domain CH PF00307.31 PVD27575.1 - 7.6e-16 58.2 0.0 2.6e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD27575.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 CAMSAP CH domain TetR_C_13 PF16925.5 PVD27575.1 - 0.18 11.7 2.4 0.8 9.7 2.4 2.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4407 PF14362.6 PVD27575.1 - 0.23 10.8 11.8 0.62 9.4 11.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HisKA_2 PF07568.12 PVD27575.1 - 0.62 10.2 5.4 8.2 6.6 2.1 3.7 1 1 1 2 2 2 0 Histidine kinase ALMT PF11744.8 PVD27575.1 - 1.1 8.0 10.5 0.36 9.6 6.2 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter ADIP PF11559.8 PVD27575.1 - 1.2 9.2 26.3 0.051 13.7 14.7 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 PVD27575.1 - 2 7.0 12.6 3 6.4 12.6 1.2 1 0 0 1 1 1 0 AAA domain Nif11 PF07862.11 PVD27575.1 - 3.5 8.0 8.3 1.5 9.2 0.2 3.4 3 0 0 3 3 3 0 Nif11 domain DUF641 PF04859.12 PVD27575.1 - 4.9 7.5 20.3 6.1 7.2 7.3 3.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GAS PF13851.6 PVD27575.1 - 6.7 6.0 33.3 1.8 7.9 11.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 PVD27575.1 - 8.6 6.8 32.0 1.3 9.4 7.7 4.6 2 1 2 4 4 4 0 Csm1 N-terminal domain zf-CXXC PF02008.20 PVD27576.1 - 1e-11 44.6 18.0 1e-11 44.6 18.0 5.3 5 0 0 5 5 5 1 CXXC zinc finger domain PHD PF00628.29 PVD27576.1 - 2e-11 43.6 76.3 1.6e-07 31.1 13.2 5.0 4 1 1 5 5 5 3 PHD-finger FYRN PF05964.14 PVD27577.1 - 2.5e-11 43.2 0.0 5.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 PVD27577.1 - 4.7e-11 42.8 9.2 2.3e-10 40.6 9.2 2.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PVD27577.1 - 4.1e-08 33.4 12.7 1.2e-07 31.9 12.7 1.9 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-3CxxC_2 PF17180.4 PVD27578.1 - 0.016 15.9 0.3 0.058 14.1 0.3 2.0 1 0 0 1 1 1 0 Zinc-binding domain zf-C2H2_jaz PF12171.8 PVD27578.1 - 0.039 14.3 0.6 0.17 12.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PVD27578.1 - 0.085 13.3 0.3 0.37 11.3 0.3 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type SET PF00856.28 PVD27579.1 - 1.5e-24 87.3 0.6 5.1e-24 85.5 0.6 1.9 1 1 0 1 1 1 1 SET domain FYRC PF05965.14 PVD27579.1 - 8.8e-23 80.3 0.0 2.4e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus zf-RING_UBOX PF13445.6 PVD27580.1 - 5.3e-12 45.6 8.3 1.4e-11 44.2 8.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD27580.1 - 2.9e-09 36.6 7.0 2.9e-09 36.6 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD27580.1 - 7.3e-09 35.7 6.3 7.3e-09 35.7 6.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD27580.1 - 2.7e-07 30.8 7.9 2.7e-07 30.8 7.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD27580.1 - 4.5e-06 26.4 10.0 4.5e-06 26.4 10.0 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD27580.1 - 1.6e-05 24.6 7.2 1.6e-05 24.6 7.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD27580.1 - 4.7e-05 23.2 6.4 4.7e-05 23.2 6.4 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD27580.1 - 7.5e-05 22.6 9.4 7.5e-05 22.6 9.4 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-B_box PF00643.24 PVD27580.1 - 0.0011 19.1 3.9 0.0011 19.1 3.9 3.2 3 1 0 3 3 3 1 B-box zinc finger Spc7 PF08317.11 PVD27580.1 - 0.0037 16.2 2.6 0.0055 15.6 2.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-H2C2_2 PF13465.6 PVD27580.1 - 0.0058 17.0 0.8 0.53 10.8 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain GAGA PF09237.11 PVD27580.1 - 0.0073 16.1 12.1 0.097 12.5 0.5 4.1 3 1 1 4 4 4 1 GAGA factor zf-Nse PF11789.8 PVD27580.1 - 0.0073 16.1 7.5 0.0082 15.9 5.9 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PVD27580.1 - 0.017 15.0 1.4 0.053 13.4 1.4 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ELF PF03317.13 PVD27580.1 - 0.079 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 ELF protein U-box PF04564.15 PVD27580.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 U-box domain Zn-C2H2_12 PF18112.1 PVD27580.1 - 0.15 12.5 2.3 16 6.0 0.2 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF745 PF05335.13 PVD27580.1 - 0.19 11.4 3.7 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CK_II_beta PF01214.18 PVD27580.1 - 0.85 9.4 4.8 2.8 7.7 0.3 2.6 2 1 1 3 3 3 0 Casein kinase II regulatory subunit zinc_ribbon_4 PF13717.6 PVD27580.1 - 1.7 8.6 6.7 2.4 8.2 0.0 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_11 PF17123.5 PVD27580.1 - 4.1 7.2 7.3 0.4 10.5 2.3 2.1 2 0 0 2 2 1 0 RING-like zinc finger IBR PF01485.21 PVD27580.1 - 7.7 6.8 12.2 1.1 9.5 2.0 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain ATP-gua_PtransN PF02807.15 PVD27581.1 - 0.0078 16.6 8.5 3.2 8.2 0.5 5.8 2 2 3 5 5 5 1 ATP:guanido phosphotransferase, N-terminal domain Antig_Caf1 PF09255.10 PVD27581.1 - 0.17 12.0 9.6 14 5.8 0.2 4.5 2 2 2 5 5 5 0 Caf1 Capsule antigen C1q PF00386.21 PVD27582.1 - 1.1e-09 38.5 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 C1q domain I-set PF07679.16 PVD27584.1 - 5.1e-22 77.7 1.2 1.1e-07 31.8 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27584.1 - 1.1e-21 77.2 1.1 5.6e-10 39.7 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27584.1 - 7.3e-14 51.9 0.7 5.9e-05 23.3 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD27584.1 - 1.1e-13 51.2 1.9 1.7e-05 24.9 0.0 3.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 PVD27584.1 - 1.7e-11 44.1 7.0 0.0004 20.5 0.0 4.4 4 1 0 4 4 4 2 Immunoglobulin domain Ig_6 PF18452.1 PVD27584.1 - 1.4e-06 27.8 0.0 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.16 PVD27584.1 - 1.2e-05 24.3 0.8 0.065 12.0 0.1 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.12 PVD27584.1 - 0.076 13.1 1.9 0.26 11.4 0.0 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain F5_F8_type_C PF00754.25 PVD27585.1 - 1.5e-21 76.9 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain CBM_14 PF01607.24 PVD27585.1 - 6.5e-05 23.0 9.9 0.00022 21.3 9.9 1.9 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CUE PF02845.16 PVD27586.1 - 3.6e-06 26.6 0.0 7.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain Ig_3 PF13927.6 PVD27587.1 - 4.6e-22 78.4 0.7 1.1e-05 25.9 0.2 5.9 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 PVD27587.1 - 3.2e-20 72.2 0.5 4.6e-07 30.1 0.2 4.9 4 1 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 PVD27587.1 - 9.1e-20 70.5 0.4 4.9e-07 29.7 0.0 6.2 6 0 0 6 6 6 3 Immunoglobulin I-set domain fn3 PF00041.21 PVD27587.1 - 5.3e-12 45.9 0.1 1.3e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.25 PVD27587.1 - 2.1e-07 31.0 5.4 0.0086 16.2 0.1 5.1 5 1 0 5 5 5 1 Immunoglobulin domain V-set PF07686.17 PVD27587.1 - 1.5e-05 25.1 3.7 0.028 14.6 0.3 4.8 4 1 0 4 4 4 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 PVD27587.1 - 3.1e-05 24.5 0.5 0.00027 21.5 0.1 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 PVD27587.1 - 0.0014 18.5 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 Tissue factor C2-set_2 PF08205.12 PVD27587.1 - 0.0049 16.9 0.1 4.6 7.4 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD27587.1 - 0.016 15.2 0.0 1 9.5 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain fn3_4 PF16794.5 PVD27587.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 Fibronectin-III type domain RIFIN PF02009.16 PVD27587.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Rifin SMP_LBD PF17047.5 PVD27587.1 - 0.15 11.5 0.0 0.55 9.7 0.0 1.8 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Ig_4 PF16680.5 PVD27587.1 - 0.39 11.0 1.4 4.2 7.7 0.0 3.1 3 0 0 3 3 2 0 T-cell surface glycoprotein CD3 delta chain T4_deiodinase PF00837.17 PVD27588.1 - 2.9e-22 79.1 0.0 3.2e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Adap_comp_sub PF00928.21 PVD27589.1 - 2.5e-26 92.6 0.0 3.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PVD27589.1 - 3.3e-08 33.6 0.5 6.1e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain CDC37_N PF03234.14 PVD27589.1 - 0.033 15.1 1.6 1.3 10.0 0.0 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Ig_3 PF13927.6 PVD27590.1 - 2.5e-176 572.7 99.9 1.3e-13 51.4 0.8 17.4 17 0 0 17 17 17 16 Immunoglobulin domain I-set PF07679.16 PVD27590.1 - 2.7e-148 482.5 15.9 9e-12 44.9 0.0 17.1 17 1 0 17 17 17 15 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27590.1 - 1.6e-119 390.5 86.5 4.1e-08 33.4 0.2 17.0 17 0 0 17 17 17 16 Immunoglobulin domain ig PF00047.25 PVD27590.1 - 1.4e-112 368.1 70.4 9.6e-09 35.3 0.1 17.1 17 1 0 17 17 17 15 Immunoglobulin domain V-set PF07686.17 PVD27590.1 - 7.2e-71 235.3 75.9 7.2e-06 26.1 0.1 25.5 16 13 2 18 18 17 14 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD27590.1 - 2.1e-25 88.6 1.6 2.5 8.2 0.0 14.7 15 0 0 15 15 15 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD27590.1 - 1.1e-22 79.9 35.8 3.4e-07 30.2 0.1 14.0 14 0 0 14 14 14 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD27590.1 - 4.1e-22 78.3 20.9 0.039 14.3 0.0 13.8 15 0 0 15 15 14 8 Immunoglobulin C1-set domain Ig_6 PF18452.1 PVD27590.1 - 1.6e-16 59.6 4.1 1.5 8.5 0.0 12.2 14 0 0 14 14 14 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD27590.1 - 1.3e-14 54.0 20.7 0.033 14.2 0.0 14.3 14 3 0 14 14 14 3 C17orf99 Ig domain DUF3887 PF13026.6 PVD27590.1 - 0.002 18.9 0.5 19 6.1 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) DUF3085 PF11284.8 PVD27590.1 - 0.0086 16.4 0.5 22 5.5 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3085) Adeno_E3_CR1 PF02440.15 PVD27590.1 - 0.03 14.1 12.4 1.3 8.9 0.0 8.1 10 0 0 10 10 10 0 Adenovirus E3 region protein CR1 ANAPC4_WD40 PF12894.7 PVD27590.1 - 0.062 13.6 0.0 42 4.5 0.0 5.5 7 0 0 7 7 7 0 Anaphase-promoting complex subunit 4 WD40 domain Orf78 PF06024.12 PVD27590.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 PVD27590.1 - 0.15 12.0 0.0 0.63 9.9 0.0 2.1 1 0 0 1 1 1 0 TMEM154 protein family CitF PF04223.12 PVD27590.1 - 6.6 5.5 13.0 5.9 5.7 0.5 3.3 3 0 0 3 3 3 0 Citrate lyase, alpha subunit (CitF) SOCS_box PF07525.16 PVD27591.1 - 0.00086 19.6 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD27592.1 - 7.6e-58 192.2 7.9 8.8e-09 35.7 0.0 10.6 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27592.1 - 1.1e-52 176.6 8.6 2.7e-13 50.3 0.0 7.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27592.1 - 1e-43 145.9 24.7 0.00017 21.9 0.2 12.3 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 PVD27592.1 - 2.1e-43 141.3 11.3 0.0061 17.0 0.0 12.4 12 1 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 PVD27592.1 - 6.7e-37 125.1 14.3 1e-06 28.9 0.0 9.3 6 3 2 8 8 8 7 Ankyrin repeats (many copies) VCBS PF13517.6 PVD27593.1 - 1.1e-08 35.5 8.5 0.0059 17.2 0.2 4.2 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PVD27593.1 - 2.5e-06 27.5 18.1 0.053 13.7 1.1 5.0 4 0 0 4 4 4 3 FG-GAP repeat PQQ PF01011.21 PVD27593.1 - 0.00047 20.0 0.0 0.051 13.5 0.0 3.6 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_2 PF13360.6 PVD27593.1 - 0.0023 17.5 0.0 0.021 14.4 0.0 2.3 1 1 2 3 3 3 1 PQQ-like domain EF-hand_1 PF00036.32 PVD27593.1 - 0.056 13.0 1.2 0.73 9.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 PVD27593.1 - 0.52 9.9 0.0 0.52 9.9 0.0 2.6 3 0 0 3 3 3 0 EF hand E1-E2_ATPase PF00122.20 PVD27594.1 - 3.4e-45 153.8 2.0 8.5e-45 152.5 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PVD27594.1 - 5.3e-40 137.1 0.0 5.3e-40 137.1 0.0 2.9 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 PVD27594.1 - 4.4e-22 78.0 0.0 7.9e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PVD27594.1 - 1.2e-18 66.5 0.0 2.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PVD27594.1 - 2.3e-16 60.7 0.0 1.2e-10 42.1 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4401 PF14351.6 PVD27594.1 - 0.031 13.6 0.2 0.031 13.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) HAD PF12710.7 PVD27594.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MgtE PF01769.16 PVD27594.1 - 0.6 10.5 7.7 3 8.3 5.3 2.6 2 0 0 2 2 2 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 PVD27594.1 - 7.6 6.6 7.9 50 4.0 4.6 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III E1-E2_ATPase PF00122.20 PVD27595.1 - 4.1e-42 143.8 0.2 4.1e-42 143.8 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PVD27595.1 - 4.6e-24 84.3 0.1 8e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 PVD27595.1 - 6.9e-22 78.0 2.4 8.4e-20 71.2 0.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PVD27595.1 - 3.1e-20 73.4 0.0 5.2e-18 66.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PVD27595.1 - 3e-17 62.1 0.0 5.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PVD27595.1 - 1.7e-05 24.7 4.2 0.00053 19.8 0.3 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD27595.1 - 0.054 13.9 0.1 0.26 11.7 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MgtE PF01769.16 PVD27595.1 - 0.33 11.4 8.9 0.85 10.0 4.7 2.4 2 0 0 2 2 2 0 Divalent cation transporter Cytochrome-c551 PF10643.9 PVD27595.1 - 0.8 9.2 3.1 5.7 6.5 1.0 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Sdh_cyt PF01127.22 PVD27595.1 - 1.6 8.8 5.0 0.64 10.1 1.5 2.1 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phage_holin_3_6 PF07332.11 PVD27595.1 - 2.7 8.1 11.8 13 5.9 0.6 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 PVD27595.1 - 3.1 6.5 7.4 9.3 4.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cation_ATPase_N PF00690.26 PVD27596.1 - 5e-05 22.9 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Chorismate_bind PF00425.18 PVD27596.1 - 0.035 13.7 0.1 0.038 13.5 0.1 1.0 1 0 0 1 1 1 0 chorismate binding enzyme Cation_ATPase_C PF00689.21 PVD27597.1 - 7.4e-45 152.9 0.1 7.4e-45 152.9 0.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PVD27597.1 - 1.7e-43 148.3 0.7 1.7e-43 148.3 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PVD27597.1 - 3.5e-19 69.9 0.0 4.7e-10 40.1 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PVD27597.1 - 2e-17 62.6 0.0 3.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PVD27597.1 - 2.8e-06 27.2 0.7 0.00059 19.7 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PVD27597.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 PVD27597.1 - 0.11 12.8 0.1 0.73 10.2 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MgtE PF01769.16 PVD27597.1 - 0.17 12.3 9.7 0.71 10.3 4.7 2.7 3 0 0 3 3 3 0 Divalent cation transporter RTP PF02334.16 PVD27597.1 - 0.48 11.1 2.2 1.1 10.0 2.2 1.5 1 0 0 1 1 1 0 Replication terminator protein ApeC PF16977.5 PVD27599.1 - 8.3e-34 117.3 0.1 1.1e-31 110.4 0.1 2.3 1 1 0 1 1 1 1 C-terminal domain of apextrin MACPF PF01823.19 PVD27599.1 - 7.7e-08 32.7 0.0 4.5e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 MAC/Perforin domain CBM_14 PF01607.24 PVD27600.1 - 0.0013 18.9 8.9 0.0013 18.9 8.9 2.7 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain gp32 PF08804.10 PVD27600.1 - 0.42 10.7 4.5 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 gp32 DNA binding protein like Nop14 PF04147.12 PVD27600.1 - 4.8 5.3 13.7 6.5 4.8 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family CBM_14 PF01607.24 PVD27601.1 - 1.9e-08 34.4 5.3 1.9e-08 34.4 5.3 1.5 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain TSP_1 PF00090.19 PVD27602.1 - 3.4e-157 510.6 350.6 8e-11 42.0 8.0 19.1 19 0 0 19 19 19 18 Thrombospondin type 1 domain CBM_14 PF01607.24 PVD27603.1 - 3e-07 30.5 5.2 5.2e-07 29.7 5.2 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain NmrA PF05368.13 PVD27604.1 - 4.3e-18 65.7 0.0 5.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PVD27604.1 - 0.00086 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PVD27604.1 - 0.16 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RhoGAP PF00620.27 PVD27605.1 - 2.8e-16 59.7 0.0 7.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.24 PVD27605.1 - 4.9e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 PX domain DHC_N1 PF08385.12 PVD27606.1 - 3.9e-44 151.2 0.3 5.5e-44 150.8 0.3 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 E2F_CC-MB PF16421.5 PVD27606.1 - 0.11 12.9 0.1 0.82 10.1 0.0 2.2 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain DHC_N2 PF08393.13 PVD27607.1 - 3.9e-85 286.4 9.0 3.9e-85 286.4 9.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 PVD27607.1 - 6.5e-72 242.9 0.0 6.5e-72 242.9 0.0 2.4 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PVD27607.1 - 1.4e-59 201.7 0.1 3.6e-55 187.2 0.2 3.0 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 PVD27607.1 - 7.6e-45 152.6 0.0 9.7e-35 119.7 0.0 3.6 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_C PF18199.1 PVD27607.1 - 7.5e-41 140.3 0.6 2.8e-40 138.5 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD27607.1 - 1.2e-39 136.3 1.3 2.1e-37 128.9 0.1 3.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD27607.1 - 6.2e-29 100.7 0.0 7.1e-28 97.2 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 PVD27607.1 - 5.4e-26 91.4 0.0 9.5e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD27607.1 - 8.4e-20 71.0 3.0 2.5e-16 59.8 0.0 3.7 4 0 0 4 4 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD27607.1 - 8.3e-17 61.5 0.9 3.3e-16 59.6 0.2 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD27607.1 - 3.4e-16 59.3 0.0 1.2e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD27607.1 - 7.3e-12 45.5 0.5 0.0018 18.3 0.0 4.9 5 0 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD27607.1 - 9.9e-09 35.8 0.1 0.011 16.2 0.0 4.8 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 PVD27607.1 - 3.9e-06 27.2 0.3 0.1 12.8 0.0 4.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 PVD27607.1 - 1.2e-05 25.3 0.7 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_lid_11 PF18198.1 PVD27607.1 - 4.3e-05 23.4 0.0 0.00031 20.6 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PVD27607.1 - 0.00013 22.4 0.0 1.7 9.1 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PVD27607.1 - 0.00037 20.9 0.0 0.28 11.6 0.0 3.5 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.6 PVD27607.1 - 0.0012 19.2 0.0 2 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PVD27607.1 - 0.0027 17.6 0.7 3.8 7.4 0.0 4.2 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 PVD27607.1 - 0.0047 16.9 0.0 2 8.2 0.0 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 PVD27607.1 - 0.015 15.4 0.6 12 6.1 0.0 4.5 4 0 0 4 4 4 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 PVD27607.1 - 0.026 14.3 0.1 1.7 8.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 PVD27607.1 - 0.042 14.1 0.0 4.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 PVD27607.1 - 0.071 12.5 0.0 8.3 5.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 PVD27607.1 - 0.075 12.7 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD27607.1 - 0.083 13.4 11.5 1.3 9.6 0.0 4.3 4 0 0 4 4 2 0 ABC transporter Viral_helicase1 PF01443.18 PVD27607.1 - 0.12 12.1 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FliT PF05400.13 PVD27607.1 - 1.3 9.8 6.1 3.3 8.6 3.0 3.6 2 0 0 2 2 1 0 Flagellar protein FliT Laminin_II PF06009.12 PVD27607.1 - 3.5 7.7 6.8 1.6 8.7 0.5 3.9 3 0 0 3 3 2 0 Laminin Domain II YabA PF06156.13 PVD27607.1 - 4.6 7.9 9.3 9.5 6.9 2.8 4.6 2 1 0 2 2 2 0 Initiation control protein YabA Pex19 PF04614.12 PVD27608.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Pex19 protein family Complex1_49kDa PF00346.19 PVD27609.1 - 3.9e-96 321.3 0.0 5.7e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 PVD27609.1 - 0.028 13.3 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Bud13 PF09736.9 PVD27610.1 - 1.1e-49 168.5 8.5 1.1e-49 168.5 8.5 4.7 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex DUF3654 PF12376.8 PVD27610.1 - 1.8 8.7 8.1 1.2 9.4 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) MRP-L28 PF09812.9 PVD27611.1 - 3.4e-45 154.1 9.0 3.7e-45 153.9 9.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Tho1_MOS11_C PF18592.1 PVD27611.1 - 0.64 9.9 6.0 0.54 10.1 1.8 2.4 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain RRM_1 PF00076.22 PVD27612.1 - 5.4e-16 58.2 0.1 9.6e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF347 PF03988.12 PVD27615.1 - 0.086 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Phage_spike PF18715.1 PVD27616.1 - 0.079 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage spike trimer ABC_membrane PF00664.23 PVD27617.1 - 4.1e-22 79.1 4.7 1.8e-09 37.7 0.0 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27617.1 - 4.1e-21 75.9 1.4 4.8e-21 75.7 0.1 1.8 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 PVD27617.1 - 0.00032 20.8 0.3 0.0023 18.0 0.2 2.1 2 0 0 2 2 2 1 Dynamin family SMC_N PF02463.19 PVD27617.1 - 0.0013 18.2 1.5 0.41 10.0 0.5 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27617.1 - 0.0017 18.4 0.1 0.0037 17.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27617.1 - 0.0025 18.2 0.0 0.0064 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PVD27617.1 - 0.0052 16.7 0.4 0.01 15.8 0.4 1.4 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 PVD27617.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 PVD27617.1 - 0.22 11.3 0.4 0.56 10.0 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 PVD27617.1 - 0.23 11.5 0.8 0.49 10.4 0.8 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 PVD27618.1 - 2.3e-19 70.3 0.0 9.7e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD27618.1 - 8.3e-05 22.1 1.7 0.0065 15.9 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 PVD27618.1 - 0.0072 16.1 0.6 0.58 9.9 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase IstB_IS21 PF01695.17 PVD27618.1 - 0.018 14.8 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 PVD27618.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PVD27618.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_membrane PF00664.23 PVD27619.1 - 1.5e-69 234.8 25.8 1.7e-35 123.0 10.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27619.1 - 6.7e-47 159.4 6.8 1.4e-29 103.3 0.0 3.9 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PVD27619.1 - 6.2e-11 42.2 0.0 3.9e-05 23.2 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27619.1 - 6.7e-07 29.4 1.1 0.0069 16.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27619.1 - 2.5e-06 28.0 0.4 0.017 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PVD27619.1 - 0.00025 21.0 0.2 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 PVD27619.1 - 0.0013 18.9 3.6 0.61 10.1 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain GTP_EFTU PF00009.27 PVD27619.1 - 0.0026 17.3 0.0 0.037 13.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PVD27619.1 - 0.01 16.1 1.8 4.5 7.6 0.0 3.5 2 1 0 2 2 2 0 AAA domain CSD PF00313.22 PVD27619.1 - 0.011 15.6 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain AAA_7 PF12775.7 PVD27619.1 - 0.012 15.1 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 PVD27619.1 - 0.02 14.6 2.4 2 8.2 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 PVD27619.1 - 0.049 13.4 0.1 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MTABC_N PF16185.5 PVD27619.1 - 0.079 12.5 8.8 0.038 13.5 4.0 2.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Dynamin_N PF00350.23 PVD27619.1 - 0.079 13.0 7.4 0.058 13.5 2.2 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 PVD27619.1 - 0.11 12.7 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD27619.1 - 0.22 11.8 2.1 18 5.6 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 PVD27619.1 - 0.23 11.0 0.6 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 PVD27619.1 - 0.27 10.8 0.7 26 4.3 0.2 2.9 2 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 PVD27619.1 - 0.81 10.1 3.1 31 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 PVD27620.1 - 9.5e-71 238.6 23.4 1.3e-35 123.4 8.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27620.1 - 5.8e-49 166.1 0.2 5.8e-26 91.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27620.1 - 1.2e-08 34.6 7.8 0.00039 19.9 0.1 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27620.1 - 2e-06 27.8 0.7 0.048 13.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27620.1 - 3.1e-06 27.7 2.4 0.026 14.9 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 PVD27620.1 - 0.00062 20.0 1.5 2.5 8.4 0.6 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PVD27620.1 - 0.0029 17.3 2.5 1.1 9.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD27620.1 - 0.0029 17.5 2.6 0.17 11.7 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 PVD27620.1 - 0.025 14.1 0.1 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 PVD27620.1 - 0.038 14.2 0.3 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 PVD27620.1 - 0.044 13.9 0.2 0.044 13.9 0.2 2.7 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 PVD27620.1 - 0.049 13.4 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD27620.1 - 0.077 12.2 1.3 8.9 5.4 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 PVD27620.1 - 0.11 11.4 0.3 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 PVD27620.1 - 0.17 11.1 1.3 15 4.8 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 PVD27620.1 - 1.4 8.9 12.3 1.1 9.3 0.4 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 PVD27620.1 - 1.8 8.3 4.9 19 4.9 0.3 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_membrane PF00664.23 PVD27621.1 - 1.8e-71 241.0 30.6 7.7e-43 147.1 12.7 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27621.1 - 4.6e-52 176.2 0.1 1.5e-29 103.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27621.1 - 1.9e-09 37.3 6.0 0.0003 20.3 0.1 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27621.1 - 2.4e-07 31.3 0.3 0.0069 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27621.1 - 1.7e-06 28.1 1.5 0.019 15.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27621.1 - 0.0013 18.7 3.9 0.1 12.5 0.5 2.8 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PVD27621.1 - 0.0037 17.5 0.8 2.4 8.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PVD27621.1 - 0.0082 15.9 3.3 0.5 10.1 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 PVD27621.1 - 0.014 14.9 0.3 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 PVD27621.1 - 0.014 15.1 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD27621.1 - 0.015 15.5 0.7 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 PVD27621.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.9 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 PVD27621.1 - 0.021 14.4 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 PVD27621.1 - 0.14 11.1 2.8 5.2 6.0 0.4 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 PVD27621.1 - 0.17 10.7 0.3 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 PVD27621.1 - 0.24 10.7 2.4 8.4 5.6 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 PVD27621.1 - 0.25 11.0 1.5 4.7 6.9 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 PVD27621.1 - 0.33 10.6 2.0 26 4.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 PVD27621.1 - 1.5 8.8 12.6 0.24 11.4 0.4 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 PVD27622.1 - 5.5e-53 179.1 0.2 1.6e-29 103.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PVD27622.1 - 2.8e-35 122.3 14.4 3.5e-34 118.7 8.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 PVD27622.1 - 2.6e-08 33.6 7.9 0.00029 20.3 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27622.1 - 5.2e-06 27.0 0.2 0.016 15.6 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27622.1 - 5e-05 23.4 2.2 0.19 11.8 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27622.1 - 0.00073 19.5 1.1 0.22 11.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 PVD27622.1 - 0.0013 18.9 3.0 0.39 10.8 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 PVD27622.1 - 0.0043 16.8 3.2 1.6 8.5 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Roc PF08477.13 PVD27622.1 - 0.034 14.4 0.2 7.5 6.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 PVD27622.1 - 0.049 13.1 0.5 11 5.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 PVD27622.1 - 0.063 12.8 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 PVD27622.1 - 0.096 12.4 0.1 3.5 7.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 PVD27622.1 - 0.12 12.0 0.0 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 PVD27622.1 - 0.18 12.0 3.7 11 6.3 0.1 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PVD27622.1 - 0.24 11.5 6.2 0.32 11.1 1.2 2.5 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 PVD27622.1 - 1.9 8.2 3.9 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC_membrane PF00664.23 PVD27623.1 - 3e-09 36.9 6.7 3e-09 36.9 6.7 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF2618 PF10940.8 PVD27623.1 - 2.2 8.2 7.1 0.12 12.2 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) Aldo_ket_red PF00248.21 PVD27624.1 - 6.3e-58 196.3 0.0 7e-56 189.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 PVD27625.1 - 1.4e-60 205.3 28.9 6.7e-42 144.0 15.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27625.1 - 1.8e-22 80.3 6.3 8e-07 29.6 0.0 4.0 3 1 1 4 4 4 3 ABC transporter SMC_N PF02463.19 PVD27625.1 - 6.3e-07 29.1 2.4 0.0012 18.3 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 PVD27625.1 - 9.6e-05 22.5 0.1 0.00024 21.2 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PVD27625.1 - 0.0033 17.5 0.5 0.011 15.9 0.5 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27625.1 - 0.015 15.2 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PVD27625.1 - 0.022 15.2 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 PVD27625.1 - 0.03 13.9 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PVD27625.1 - 0.15 12.3 0.2 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 PVD27626.1 - 7.8e-76 255.3 29.2 8.3e-40 137.2 14.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27626.1 - 2.4e-53 180.3 0.1 4.7e-30 104.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PVD27626.1 - 7.9e-09 35.3 7.0 0.0004 19.9 0.1 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27626.1 - 1.5e-06 28.2 1.1 0.0064 16.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27626.1 - 2.4e-06 28.1 0.3 0.0046 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PVD27626.1 - 0.00019 21.4 0.7 0.039 13.9 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 PVD27626.1 - 0.00027 21.1 3.5 0.37 10.8 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 PVD27626.1 - 0.0028 17.2 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 PVD27626.1 - 0.011 16.0 2.6 2 8.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PVD27626.1 - 0.012 14.5 0.3 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 PVD27626.1 - 0.014 15.1 1.9 1.5 8.6 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD27626.1 - 0.015 15.4 5.3 0.023 14.8 1.0 2.6 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 PVD27626.1 - 0.018 14.6 0.2 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 PVD27626.1 - 0.055 12.4 0.3 3.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PVD27626.1 - 0.092 12.5 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PVD27626.1 - 0.11 11.7 0.6 4.8 6.3 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Roc PF08477.13 PVD27626.1 - 0.19 11.9 0.5 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 PVD27626.1 - 0.23 11.1 0.8 34 4.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 PVD27626.1 - 0.32 10.3 1.4 7.7 5.8 0.1 2.7 2 0 0 2 2 2 0 AIG1 family NB-ARC PF00931.22 PVD27626.1 - 0.79 8.9 2.5 4.2 6.5 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain GlpM PF06942.12 PVD27626.1 - 9.2 6.7 9.9 31 5.1 2.0 3.0 2 0 0 2 2 2 0 GlpM protein ABC_membrane PF00664.23 PVD27627.1 - 7.2e-24 84.9 4.8 7.2e-24 84.9 4.8 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27627.1 - 8.6e-20 71.7 0.4 2.3e-19 70.3 0.1 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PVD27627.1 - 0.00066 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27627.1 - 0.0014 18.7 0.1 0.0034 17.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 PVD27627.1 - 0.0071 15.8 3.1 0.68 9.3 0.4 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain GTP_EFTU PF00009.27 PVD27627.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2075 PF09848.9 PVD27627.1 - 0.068 12.4 0.4 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 PVD27627.1 - 0.078 12.9 3.1 0.054 13.4 0.9 1.8 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 PVD27627.1 - 0.15 12.1 6.1 0.039 14.0 2.5 1.8 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 PVD27627.1 - 2.1 8.4 6.0 0.35 10.9 1.4 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 PVD27628.1 - 9.5e-28 97.4 0.2 1.9e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 PVD27628.1 - 7.4e-07 28.8 1.4 5.7e-05 22.7 0.2 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 PVD27628.1 - 0.00056 19.6 0.2 0.0012 18.5 0.2 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_24 PF13479.6 PVD27628.1 - 0.013 15.2 0.2 0.042 13.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD27628.1 - 0.051 14.0 0.2 0.12 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27628.1 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 PVD27628.1 - 0.099 12.7 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 PVD27628.1 - 0.18 11.6 0.1 5 6.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD27628.1 - 0.21 11.8 1.1 3.1 8.1 0.8 2.4 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 PVD27629.1 - 2.6e-74 250.3 31.3 1.2e-39 136.6 17.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27629.1 - 8.8e-53 178.5 0.3 2.5e-29 102.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27629.1 - 1.5e-08 34.3 8.1 0.00036 20.0 0.1 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27629.1 - 1.9e-06 28.4 0.3 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27629.1 - 2.4e-06 27.6 1.4 0.0068 16.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 PVD27629.1 - 0.0008 19.6 3.4 0.5 10.4 0.8 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 PVD27629.1 - 0.001 19.0 1.7 0.081 12.8 0.3 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 PVD27629.1 - 0.0026 17.3 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 PVD27629.1 - 0.0045 17.1 3.1 0.014 15.5 0.3 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 PVD27629.1 - 0.0093 16.2 2.8 3.2 8.0 0.0 3.6 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 PVD27629.1 - 0.02 14.5 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 PVD27629.1 - 0.021 14.6 2.4 1.5 8.6 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 PVD27629.1 - 0.033 13.1 0.3 4.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 PVD27629.1 - 0.041 12.9 0.3 2 7.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PVD27629.1 - 0.042 13.6 0.0 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD27629.1 - 0.14 12.3 0.9 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 PVD27629.1 - 0.37 9.9 1.9 3.9 6.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 PVD27629.1 - 1.5 8.6 4.0 10 5.8 0.3 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 PVD27629.1 - 1.6 8.4 3.1 36 4.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 PVD27630.1 - 0.0073 16.0 0.8 0.018 14.7 0.8 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 PVD27631.1 - 2.4e-62 211.1 19.1 2.1e-35 122.7 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27631.1 - 1.8e-54 184.0 0.2 3.2e-30 105.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27631.1 - 1.2e-11 44.5 0.4 0.00038 20.0 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD27631.1 - 5.2e-07 29.7 1.3 0.0081 16.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27631.1 - 1e-06 29.3 0.2 0.0075 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PVD27631.1 - 5.1e-05 23.2 0.6 0.025 14.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 PVD27631.1 - 0.00098 19.3 2.9 0.34 11.0 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain GTP_EFTU PF00009.27 PVD27631.1 - 0.0013 18.4 0.1 0.026 14.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PVD27631.1 - 0.0037 17.6 2.3 2.6 8.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PVD27631.1 - 0.0049 16.9 0.3 0.0049 16.9 0.3 2.8 3 0 0 3 3 3 1 Dynamin family AAA_7 PF12775.7 PVD27631.1 - 0.0062 16.1 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 PVD27631.1 - 0.0083 15.9 3.2 0.74 9.6 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 PVD27631.1 - 0.012 15.3 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD27631.1 - 0.013 15.7 0.5 3 8.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 PVD27631.1 - 0.042 14.0 0.0 0.89 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PVD27631.1 - 0.07 12.7 0.2 17 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD27631.1 - 0.13 11.4 1.6 4.1 6.5 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 PVD27631.1 - 0.21 12.1 3.0 19 5.7 0.1 3.0 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 PVD27631.1 - 0.34 10.6 3.3 7.3 6.3 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 PVD27631.1 - 0.38 10.1 1.7 4.7 6.5 0.1 2.3 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 PVD27631.1 - 0.46 10.1 2.1 1.3 8.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 PVD27631.1 - 0.53 10.0 2.2 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein SSF PF00474.17 PVD27632.1 - 3.2e-31 108.6 27.0 8.3e-31 107.2 27.0 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family DUF1744 PF08490.12 PVD27633.1 - 4e-115 384.6 2.8 3.8e-114 381.4 2.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 PVD27633.1 - 1.3e-68 231.6 0.1 2.8e-68 230.5 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 PVD27633.1 - 2.1e-14 53.1 0.1 1.3e-13 50.5 0.1 2.4 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 PVD27633.1 - 1.7e-09 37.7 0.1 4.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 PVD27633.1 - 8.4e-06 25.9 0.2 5.5e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 RNase_H superfamily KIX PF02172.16 PVD27634.1 - 2.3e-07 31.0 0.6 4.7e-07 30.0 0.6 1.5 1 0 0 1 1 1 1 KIX domain DNA_pol_B_exo1 PF03104.19 PVD27634.1 - 5.4e-05 22.5 0.0 9.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain KIX_2 PF16987.5 PVD27634.1 - 0.026 14.5 0.2 0.061 13.3 0.2 1.7 1 0 0 1 1 1 0 KIX domain Glycos_transf_4 PF00953.21 PVD27636.1 - 7.6e-36 123.5 13.1 7.6e-36 123.5 13.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 4 zf-C2H2_4 PF13894.6 PVD27636.1 - 0.063 14.1 0.3 0.22 12.4 0.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger VWA_2 PF13519.6 PVD27637.1 - 9.7e-09 35.8 1.1 1.1e-07 32.4 0.3 2.9 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PVD27637.1 - 1.8e-08 34.8 1.5 5.5e-08 33.3 0.1 2.5 2 2 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD27637.1 - 0.013 14.9 0.7 0.098 12.0 0.7 2.2 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Bromo_TP_like PF17027.5 PVD27637.1 - 0.03 14.5 2.9 0.11 12.6 0.4 2.4 2 0 0 2 2 2 0 Histone-fold protein NAT PF04768.13 PVD27637.1 - 0.096 12.3 2.4 2.2 7.9 0.1 3.0 2 1 0 3 3 3 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Plk4_PB2 PF18409.1 PVD27637.1 - 0.4 11.4 2.3 0.83 10.4 0.3 2.5 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 CooT PF10133.9 PVD27637.1 - 1.3 9.4 4.7 3.4 8.0 1.2 3.2 3 0 0 3 3 3 0 CO dehydrogenase accessory protein CooT ATP-synt_ab PF00006.25 PVD27638.1 - 6.3e-108 359.3 0.0 8.6e-108 358.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PVD27638.1 - 5.3e-44 149.0 0.0 9.7e-44 148.1 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 PVD27638.1 - 9.6e-14 51.7 4.5 2.3e-13 50.5 4.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Acetyltransf_1 PF00583.25 PVD27639.1 - 4.5e-16 59.1 0.1 5.7e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD27639.1 - 2.5e-10 40.6 0.1 3.5e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD27639.1 - 4.6e-09 36.3 0.1 6.3e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PVD27639.1 - 1.3e-05 25.0 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 PVD27639.1 - 4.2e-05 23.7 0.4 7.8e-05 22.8 0.4 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PVD27639.1 - 0.00023 20.9 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PVD27639.1 - 0.00049 20.8 0.0 0.00068 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PVD27639.1 - 0.0035 17.4 0.0 0.0079 16.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain WH2 PF02205.20 PVD27639.1 - 0.1 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 WH2 motif Peptidase_M1_N PF17900.1 PVD27640.1 - 5.1e-42 144.2 0.1 6.8e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 PVD27640.1 - 1.7e-10 40.9 0.2 2.9e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain SprT-like PF10263.9 PVD27640.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 SprT-like family VWA_2 PF13519.6 PVD27641.1 - 1.2e-07 32.3 0.1 1.5e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD27641.1 - 9e-06 26.0 0.1 1e-05 25.8 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain T3SS_needle_E PF08988.10 PVD27641.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DUF2023 PF09633.10 PVD27641.1 - 0.1 12.7 0.2 3.1 8.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2023) Acetyltransf_1 PF00583.25 PVD27642.1 - 1.1e-15 57.8 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD27642.1 - 3.3e-10 40.2 0.1 4.6e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD27642.1 - 1.9e-08 34.3 0.1 2.4e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PVD27642.1 - 6.9e-06 25.9 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 PVD27642.1 - 3.7e-05 23.9 0.0 4.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PVD27642.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PVD27642.1 - 0.00029 21.5 0.0 0.00043 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PVD27642.1 - 0.031 14.3 0.0 0.054 13.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF762 PF05555.11 PVD27642.1 - 0.035 13.7 0.1 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) Peptidase_M1_N PF17900.1 PVD27643.1 - 1.2e-36 126.7 0.1 1.4e-36 126.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 PVD27644.1 - 5e-38 130.8 2.6 6.1e-38 130.6 2.6 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Aminopep PF10023.9 PVD27644.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative aminopeptidase SprT-like PF10263.9 PVD27644.1 - 0.0086 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family BSP PF04450.12 PVD27644.1 - 0.051 13.4 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M48 PF01435.18 PVD27644.1 - 0.071 12.9 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 ERAP1_C PF11838.8 PVD27645.1 - 2.8e-24 86.2 1.1 3.1e-24 86.1 0.4 1.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD27645.1 - 4.1e-07 29.8 1.7 0.0026 17.3 0.3 2.2 1 1 1 2 2 2 2 Peptidase family M1 domain Post_transc_reg PF13797.6 PVD27645.1 - 0.0059 16.4 0.4 0.27 11.1 0.2 2.4 2 0 0 2 2 2 1 Post-transcriptional regulator TAD2 PF18521.1 PVD27645.1 - 0.1 12.6 0.7 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Transactivation domain 2 DUF5553 PF17707.1 PVD27646.1 - 0.03 13.8 0.2 0.067 12.6 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5553) RP-C_C PF11800.8 PVD27646.1 - 0.033 14.3 0.1 0.056 13.5 0.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Curto_V2 PF07325.11 PVD27647.1 - 0.53 10.2 8.1 0.038 13.9 1.8 2.2 1 1 1 2 2 2 0 Curtovirus V2 protein Oxidored_molyb PF00174.19 PVD27648.1 - 1.3e-37 129.1 0.1 7.7e-25 87.5 0.0 2.6 2 1 1 3 3 3 2 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PVD27648.1 - 1.7e-37 128.5 0.2 3.2e-37 127.6 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FYRN PF05964.14 PVD27648.1 - 8.1e-21 73.6 0.2 2e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus Cyt-b5 PF00173.28 PVD27648.1 - 6.1e-11 42.3 0.1 1.3e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ORC6 PF05460.13 PVD27648.1 - 0.0027 17.1 1.0 0.035 13.4 1.8 1.9 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) CPSF100_C PF13299.6 PVD27648.1 - 0.075 13.2 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 PVD27648.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 PVD27655.1 - 2.9e-85 280.5 0.0 2.7e-18 65.8 0.0 6.3 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27655.1 - 2.8e-81 268.2 1.8 2.4e-15 56.9 0.0 6.5 7 0 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 PVD27655.1 - 7.6e-49 164.0 0.0 2.8e-09 37.2 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 PVD27655.1 - 1.3e-43 147.0 0.0 1e-09 38.5 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 PVD27655.1 - 1.2e-38 131.4 6.6 8.8e-17 61.2 1.2 3.7 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 PVD27655.1 - 9.7e-30 103.0 4.3 1.3e-06 28.5 0.0 9.7 6 4 2 8 8 8 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD27655.1 - 1.2e-16 60.6 0.6 0.0047 17.0 0.0 5.7 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD27655.1 - 3.4e-11 42.5 0.0 0.0026 17.3 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain C1-set PF07654.15 PVD27655.1 - 0.0061 16.9 0.0 16 6.0 0.0 4.0 3 0 0 3 3 3 0 Immunoglobulin C1-set domain fn3_4 PF16794.5 PVD27655.1 - 0.0072 16.2 0.1 0.54 10.2 0.0 2.8 2 1 0 2 2 2 1 Fibronectin-III type domain Izumo-Ig PF16706.5 PVD27655.1 - 0.014 15.4 0.2 45 4.2 0.0 4.1 5 0 0 5 5 4 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD27655.1 - 0.019 15.5 7.4 0.02 15.5 0.2 3.7 3 1 1 4 4 3 0 Purple acid Phosphatase, N-terminal domain Homeobox_KN PF05920.11 PVD27655.1 - 0.17 11.8 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain SSF PF00474.17 PVD27656.1 - 6e-35 120.9 21.3 8.7e-35 120.4 21.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family NHL PF01436.21 PVD27658.1 - 1.8e-11 43.5 5.2 1.4e-05 24.8 0.0 4.6 5 0 0 5 5 5 3 NHL repeat zf-C3HC4 PF00097.25 PVD27658.1 - 2e-06 27.6 10.8 2e-06 27.6 10.8 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD27658.1 - 3.1e-06 27.1 11.1 3.1e-06 27.1 11.1 3.1 2 0 0 2 2 2 1 RING-type zinc-finger SGL PF08450.12 PVD27658.1 - 3.3e-06 26.9 0.4 0.049 13.2 0.0 3.4 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 PVD27658.1 - 5.7e-06 26.4 20.2 1.7e-05 24.9 8.2 5.1 4 1 1 5 5 4 2 B-box zinc finger DUF3583 PF12126.8 PVD27658.1 - 1.6e-05 24.6 0.4 1.6e-05 24.6 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) zf-RING_5 PF14634.6 PVD27658.1 - 0.00044 20.2 11.5 0.00044 20.2 11.5 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD27658.1 - 0.00069 19.7 10.4 0.00069 19.7 10.4 3.3 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD27658.1 - 0.0012 19.1 14.2 0.0012 19.1 14.2 3.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD27658.1 - 0.0056 16.5 11.4 0.0056 16.5 11.4 3.7 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) HSCB_C PF07743.13 PVD27658.1 - 0.89 10.1 4.0 1.1 9.8 2.7 2.0 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain zf-UBP_var PF17807.1 PVD27658.1 - 1.5 8.7 10.5 0.71 9.7 0.5 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Ribosomal_L17 PF01196.19 PVD27659.1 - 1.7e-11 44.8 0.0 2.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 7tm_1 PF00001.21 PVD27661.1 - 7.4e-49 166.4 5.8 9.9e-49 166.0 5.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD27661.1 - 3.2e-09 36.8 11.2 7.7e-09 35.6 11.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD27661.1 - 3.5e-07 29.9 7.1 1.1e-06 28.3 7.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD27661.1 - 0.0001 22.1 8.8 0.00015 21.6 8.8 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF621 PF04789.15 PVD27661.1 - 0.082 12.1 12.3 0.13 11.4 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Maelstrom PF13017.6 PVD27662.1 - 4e-34 118.2 0.0 5.3e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box PF00505.19 PVD27662.1 - 1.5e-10 41.3 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD27662.1 - 2.4e-10 40.8 0.0 1.5e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 HMG-box domain Fibrillin_U_N PF18193.1 PVD27662.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.5 3 0 0 3 3 3 0 Fibrillin 1 unique N-terminal domain Ank_2 PF12796.7 PVD27663.1 - 8e-20 71.2 0.4 7.7e-07 29.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD27663.1 - 1.7e-19 69.3 0.5 0.039 14.4 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PVD27663.1 - 1.1e-16 61.0 0.0 0.00027 21.4 0.0 4.9 2 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD27663.1 - 1.5e-14 52.6 0.1 0.091 13.4 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PVD27663.1 - 2.7e-13 49.8 2.6 0.013 15.9 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) ABC_membrane PF00664.23 PVD27664.1 - 5.4e-70 236.2 36.0 2.3e-36 125.9 14.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27664.1 - 1.9e-53 180.6 0.4 1.9e-29 102.9 0.1 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 PVD27664.1 - 4.1e-09 36.2 8.7 0.00029 20.4 0.2 4.3 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD27664.1 - 6.1e-07 30.0 0.3 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD27664.1 - 7.2e-06 26.1 1.7 0.073 13.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD27664.1 - 0.00025 21.0 0.5 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PVD27664.1 - 0.0011 19.3 0.9 2.3 8.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PVD27664.1 - 0.0037 17.0 2.1 0.59 9.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 PVD27664.1 - 0.0051 16.6 0.0 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD27664.1 - 0.0068 15.9 0.3 3.9 6.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 PVD27664.1 - 0.021 14.9 9.2 0.47 10.5 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Roc PF08477.13 PVD27664.1 - 0.031 14.5 0.3 8.4 6.6 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PVD27664.1 - 0.052 13.1 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.6 PVD27664.1 - 0.1 12.4 1.1 12 5.5 0.0 3.6 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 PVD27664.1 - 0.16 11.5 0.6 0.99 9.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 PVD27664.1 - 0.17 10.8 0.5 7.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 PVD27664.1 - 0.37 10.0 1.4 9 5.5 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 PVD27664.1 - 0.58 9.9 2.5 31 4.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PVD27664.1 - 0.67 10.0 10.8 0.038 14.1 0.7 2.9 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 PVD27664.1 - 1.1 9.7 6.2 10 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain YwiC PF14256.6 PVD27664.1 - 4.7 7.5 11.6 11 6.3 0.4 4.0 3 1 1 4 4 4 0 YwiC-like protein Defensin_5 PF18251.1 PVD27666.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal defensin Copsin VanW PF04294.13 PVD27666.1 - 0.099 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 VanW like protein ABC_membrane PF00664.23 PVD27667.1 - 2.3e-61 207.9 22.3 5.7e-38 131.1 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27667.1 - 1.6e-32 112.9 0.1 3.9e-20 72.8 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD27667.1 - 1.6e-10 40.8 0.7 0.0001 21.8 0.0 3.3 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PVD27667.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PVD27667.1 - 0.0027 17.8 0.0 0.0091 16.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD27667.1 - 0.0054 17.1 0.2 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 PVD27667.1 - 0.0065 16.5 1.2 0.0065 16.5 1.2 1.9 2 0 0 2 2 2 1 Dynamin family Smim3 PF17307.2 PVD27667.1 - 0.046 13.2 1.6 0.12 11.9 1.6 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 GTP_EFTU PF00009.27 PVD27667.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 PVD27667.1 - 0.1 12.4 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 PVD27667.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 PVD27667.1 - 0.16 12.2 0.3 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MTABC_N PF16185.5 PVD27668.1 - 0.0076 15.8 5.2 0.015 14.8 5.2 1.4 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region Mac PF12464.8 PVD27669.1 - 0.025 14.8 1.0 1.9 8.8 0.1 3.0 3 0 0 3 3 3 0 Maltose acetyltransferase Quaking_NLS PF16551.5 PVD27669.1 - 1.3 8.7 7.5 4.8 6.9 0.4 3.5 3 0 0 3 3 3 0 Putative nuclear localisation signal of quaking MFS_1 PF07690.16 PVD27670.1 - 7.6e-46 156.6 25.6 2.2e-28 99.2 0.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 PVD27670.1 - 4.3e-07 28.8 16.0 0.00065 18.4 5.1 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 PVD27670.1 - 0.0006 18.8 19.6 0.16 10.8 4.8 3.1 2 1 0 2 2 2 2 MFS_1 like family DUF3169 PF11368.8 PVD27670.1 - 0.21 11.1 0.0 0.21 11.1 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) EphA2_TM PF14575.6 PVD27671.1 - 0.0071 17.2 0.1 0.019 15.9 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 PVD27671.1 - 0.018 15.0 0.1 0.018 15.0 0.1 1.7 2 0 0 2 2 2 0 Protocadherin Syndecan PF01034.20 PVD27671.1 - 0.065 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain ig PF00047.25 PVD27671.1 - 0.28 11.4 4.8 8.1 6.7 2.1 3.8 3 0 0 3 3 3 0 Immunoglobulin domain TMEM154 PF15102.6 PVD27671.1 - 1.6 8.6 6.6 0.087 12.7 0.8 1.9 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.11 PVD27671.1 - 8.4 6.5 13.8 0.51 10.4 1.8 2.8 3 0 0 3 3 3 0 Podoplanin Ig_3 PF13927.6 PVD27672.1 - 0.05 14.2 4.9 0.16 12.6 0.0 3.5 3 1 1 4 4 4 0 Immunoglobulin domain FSA_C PF10479.9 PVD27672.1 - 1.8 6.6 4.6 2.7 6.0 4.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ig_2 PF13895.6 PVD27673.1 - 1.4e-11 44.5 12.1 0.0014 18.9 0.7 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.6 PVD27673.1 - 3.4e-11 43.6 12.4 5.2e-06 27.0 0.7 5.0 4 1 1 5 5 5 3 Immunoglobulin domain Protocadherin PF08374.11 PVD27673.1 - 0.0012 18.9 1.3 0.019 15.0 0.3 2.4 2 0 0 2 2 2 1 Protocadherin I-set PF07679.16 PVD27673.1 - 0.0052 16.8 0.3 5.6 7.1 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain HemX PF04375.14 PVD27673.1 - 0.01 15.1 1.8 0.015 14.6 1.8 1.3 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase EphA2_TM PF14575.6 PVD27673.1 - 0.018 15.9 1.0 0.036 14.9 0.3 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WSS_VP PF12175.8 PVD27673.1 - 0.063 12.7 0.7 0.12 11.8 0.7 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP ig PF00047.25 PVD27673.1 - 0.07 13.3 9.7 0.82 9.9 0.8 4.3 4 1 0 4 4 4 0 Immunoglobulin domain PsaF PF17550.2 PVD27673.1 - 0.085 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function Podoplanin PF05808.11 PVD27674.1 - 0.00011 22.4 1.8 0.00065 19.8 0.0 2.1 2 0 0 2 2 2 1 Podoplanin FtsL PF04999.13 PVD27674.1 - 0.0063 16.5 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Cell division protein FtsL ECSCR PF15820.5 PVD27674.1 - 0.044 13.6 1.5 0.087 12.7 1.5 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator GWT1 PF06423.12 PVD27674.1 - 0.076 13.1 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 GWT1 DUF202 PF02656.15 PVD27674.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4690 PF15756.5 PVD27674.1 - 0.19 12.3 1.5 0.7 10.5 0.1 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 PVD27674.1 - 0.82 9.9 5.2 0.17 12.1 0.9 2.0 1 1 1 2 2 2 0 Glycophorin A Syndecan PF01034.20 PVD27674.1 - 4 7.4 5.9 7.8 6.5 5.9 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 PVD27675.1 - 7.9e-06 25.8 1.5 7.9e-06 25.8 1.5 2.0 2 0 0 2 2 2 1 TMEM154 protein family Sarcoglycan_2 PF05510.13 PVD27675.1 - 0.0026 16.6 0.1 0.004 16.0 0.1 1.2 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Insulin_TMD PF17870.1 PVD27675.1 - 0.0051 16.9 2.7 0.018 15.1 2.7 1.9 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Protocadherin PF08374.11 PVD27675.1 - 0.007 16.4 0.2 0.28 11.1 0.1 2.5 2 0 0 2 2 2 1 Protocadherin LAP1C PF05609.12 PVD27675.1 - 0.0083 15.3 0.5 0.013 14.6 0.5 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) EphA2_TM PF14575.6 PVD27675.1 - 0.012 16.4 0.1 0.037 14.9 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4293 PF14126.6 PVD27675.1 - 0.021 15.1 0.2 0.04 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DAG1 PF05454.11 PVD27675.1 - 0.022 14.1 2.3 0.037 13.4 1.8 1.6 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Pilin_N PF07790.11 PVD27675.1 - 0.043 14.7 3.8 0.16 12.9 3.8 2.0 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Ig_3 PF13927.6 PVD27675.1 - 0.066 13.8 0.2 0.066 13.8 0.2 3.6 2 1 1 3 3 3 0 Immunoglobulin domain DUF4064 PF13273.6 PVD27675.1 - 0.074 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Sigma_reg_N PF13800.6 PVD27675.1 - 0.087 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Orf78 PF06024.12 PVD27675.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF5385 PF17359.2 PVD27675.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RIFIN PF02009.16 PVD27675.1 - 0.49 10.2 3.3 0.24 11.3 0.2 1.8 2 0 0 2 2 2 0 Rifin DUF2771 PF10969.8 PVD27675.1 - 4.4 7.3 7.7 11 6.1 3.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2771) GAPT PF11770.8 PVD27677.1 - 0.0052 16.6 0.2 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 GRB2-binding adapter (GAPT) Adeno_E3_CR2 PF02439.15 PVD27677.1 - 0.0066 16.2 5.8 0.0066 16.2 5.8 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 RIFIN PF02009.16 PVD27677.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 PVD27677.1 - 0.026 14.4 0.3 0.065 13.2 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 PVD27677.1 - 0.04 14.2 0.0 0.04 14.2 0.0 2.0 3 0 0 3 3 1 0 Orf78 (ac78) Stevor PF17410.2 PVD27677.1 - 0.04 13.4 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame BatA PF07584.11 PVD27677.1 - 0.081 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal EphA2_TM PF14575.6 PVD27677.1 - 0.086 13.7 2.0 0.3 12.0 1.8 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD27677.1 - 0.088 12.9 2.7 0.23 11.5 2.7 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SKG6 PF08693.10 PVD27677.1 - 0.45 10.0 13.2 0.019 14.3 6.8 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF5385 PF17359.2 PVD27677.1 - 0.61 9.6 3.4 1.1 8.7 3.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2613 PF11021.8 PVD27677.1 - 1.3 9.1 8.3 10 6.4 8.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TMEM154 PF15102.6 PVD27677.1 - 3.2 7.7 17.2 89 3.0 17.2 2.8 1 1 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 PVD27679.1 - 0.0035 17.2 1.0 0.005 16.7 1.0 1.2 1 0 0 1 1 1 1 Syndecan domain UPF0016 PF01169.19 PVD27679.1 - 0.0046 17.3 0.2 0.006 16.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 DUF5453 PF17534.2 PVD27679.1 - 0.012 15.6 0.5 0.014 15.3 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Amnionless PF14828.6 PVD27679.1 - 0.028 13.3 0.0 0.028 13.3 0.0 1.0 1 0 0 1 1 1 0 Amnionless Insulin_TMD PF17870.1 PVD27679.1 - 0.029 14.4 1.3 0.041 13.9 1.3 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 PVD27679.1 - 0.029 15.2 0.0 0.031 15.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD27679.1 - 0.038 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family PUCC PF03209.15 PVD27679.1 - 0.059 12.4 0.0 0.067 12.2 0.0 1.0 1 0 0 1 1 1 0 PUCC protein ig PF00047.25 PVD27680.1 - 0.00079 19.6 2.1 0.064 13.4 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27680.1 - 0.018 15.6 8.6 1.6 9.4 0.3 3.7 2 2 1 3 3 3 0 Immunoglobulin domain TMEM154 PF15102.6 PVD27681.1 - 0.00012 22.0 7.2 0.00045 20.1 0.7 3.1 3 0 0 3 3 3 1 TMEM154 protein family CD34_antigen PF06365.12 PVD27681.1 - 0.00034 20.3 0.3 0.002 17.8 0.0 2.2 3 0 0 3 3 3 1 CD34/Podocalyxin family DUF5305 PF17231.2 PVD27681.1 - 0.00043 19.8 0.3 0.88 8.9 0.1 3.2 3 0 0 3 3 3 1 Family of unknown function (DUF5305) PRIMA1 PF16101.5 PVD27681.1 - 0.00066 19.7 2.4 2.9 7.9 0.0 3.6 3 0 0 3 3 3 1 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 PVD27681.1 - 0.00083 20.2 12.5 0.22 12.4 0.6 4.0 3 1 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD27681.1 - 0.0041 17.4 5.2 0.005 17.1 0.1 3.1 4 0 0 4 4 4 1 Orf78 (ac78) DAG1 PF05454.11 PVD27681.1 - 0.0068 15.8 7.4 0.024 14.0 0.3 2.6 3 0 0 3 3 3 1 Dystroglycan (Dystrophin-associated glycoprotein 1) UL42 PF17638.2 PVD27681.1 - 0.0085 16.1 7.0 0.032 14.2 0.2 3.5 3 0 0 3 3 3 1 HCMV UL42 DUF4448 PF14610.6 PVD27681.1 - 0.03 14.1 0.3 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Epiglycanin_C PF14654.6 PVD27681.1 - 0.082 13.0 2.4 1 9.5 0.0 2.9 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2207 PF09972.9 PVD27681.1 - 0.096 11.4 1.6 2.9 6.6 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) LRR19-TM PF15176.6 PVD27681.1 - 0.098 12.7 1.4 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF1180 PF06679.12 PVD27681.1 - 0.11 12.9 0.5 2.2 8.6 0.2 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1180) SieB PF14163.6 PVD27681.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.5 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF2140 PF09911.9 PVD27681.1 - 0.11 12.0 3.2 1 8.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4690 PF15756.5 PVD27681.1 - 0.12 13.0 0.2 0.12 13.0 0.2 3.4 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Orai-1 PF07856.12 PVD27681.1 - 0.25 11.0 3.3 4.8 6.8 1.0 2.9 2 1 0 2 2 2 0 Mediator of CRAC channel activity DUF4229 PF14012.6 PVD27681.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.9 4 0 0 4 4 3 0 Protein of unknown function (DUF4229) LapA_dom PF06305.11 PVD27681.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.1 4 0 0 4 4 2 0 Lipopolysaccharide assembly protein A domain Shisa PF13908.6 PVD27681.1 - 1.1 9.4 12.8 0.93 9.7 0.5 3.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 PVD27681.1 - 1.4 9.9 6.8 4.9 8.2 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 PVD27681.1 - 7.8 7.3 13.9 3.7 8.4 0.9 4.3 4 1 0 4 4 3 0 Cadherin cytoplasmic C-terminal Sigma_reg_N PF13800.6 PVD27681.1 - 9.5 6.6 13.4 3.9 7.8 0.9 3.7 4 0 0 4 4 3 0 Sigma factor regulator N-terminal Ig_3 PF13927.6 PVD27682.1 - 3e-05 24.5 11.4 0.084 13.5 0.6 3.1 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD27682.1 - 0.00064 19.8 12.1 0.26 11.5 1.8 3.7 2 2 1 3 3 3 3 Immunoglobulin domain Baculo_8kDa PF06096.11 PVD27682.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein EphA2_TM PF14575.6 PVD27683.1 - 6.3e-12 46.2 20.9 0.03 15.2 0.0 7.7 8 0 0 8 8 8 4 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 PVD27683.1 - 4.1e-08 33.7 120.0 0.16 12.6 1.0 21.3 22 0 0 22 22 20 6 Immunoglobulin domain RIFIN PF02009.16 PVD27683.1 - 1.9e-05 24.8 10.0 0.16 11.8 0.8 4.1 5 0 0 5 5 4 3 Rifin Protocadherin PF08374.11 PVD27683.1 - 6e-05 23.1 18.3 0.55 10.2 0.2 5.8 6 0 0 6 6 6 3 Protocadherin DUF4808 PF16066.5 PVD27683.1 - 0.00072 20.1 0.0 1.6 9.3 0.0 3.8 3 0 0 3 3 2 1 Domain of unknown function (DUF4808) ig PF00047.25 PVD27683.1 - 0.001 19.2 83.8 0.25 11.6 0.0 19.1 17 6 1 18 18 18 5 Immunoglobulin domain Stevor PF17410.2 PVD27683.1 - 0.0017 17.9 12.0 1.7 8.1 0.0 4.9 5 0 0 5 5 5 3 Subtelomeric Variable Open Reading frame Cadherin_C_2 PF16492.5 PVD27683.1 - 0.0047 17.7 2.9 26 5.6 0.0 5.5 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal Ninjurin PF04923.12 PVD27683.1 - 0.013 15.4 0.5 40 4.2 0.0 4.1 4 0 0 4 4 4 0 Ninjurin MAP17 PF15807.5 PVD27683.1 - 0.04 14.2 0.8 91 3.3 0.0 4.0 4 0 0 4 4 4 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PTP_tm PF18861.1 PVD27683.1 - 0.052 13.5 10.5 5.5 6.9 0.6 3.8 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J C1-set PF07654.15 PVD27683.1 - 0.15 12.4 26.9 17 5.9 0.2 9.1 9 0 0 9 9 7 0 Immunoglobulin C1-set domain PepSY_TM PF03929.16 PVD27683.1 - 0.16 11.6 0.1 43 3.6 0.0 3.4 4 0 0 4 4 4 0 PepSY-associated TM region TMEM154 PF15102.6 PVD27683.1 - 0.33 10.9 24.6 1 9.3 0.5 5.2 5 0 0 5 5 5 0 TMEM154 protein family ArsP_1 PF03773.13 PVD27683.1 - 0.48 9.5 9.5 11 5.0 0.1 3.9 4 0 0 4 4 4 0 Predicted permease ECSCR PF15820.5 PVD27683.1 - 0.81 9.5 20.5 3.1 7.7 0.1 5.6 6 0 0 6 6 6 0 Endothelial cell-specific chemotaxis regulator T4SS_CagC PF16943.5 PVD27683.1 - 2.1 8.6 11.4 2.2 8.5 0.0 4.7 5 0 0 5 5 4 0 Cag pathogenicity island, type IV secretory system LPG_synthase_TM PF03706.13 PVD27683.1 - 2.2 7.7 7.3 25 4.3 0.1 4.3 4 0 0 4 4 4 0 Lysylphosphatidylglycerol synthase TM region DUF4199 PF13858.6 PVD27683.1 - 2.4 8.5 9.1 24 5.3 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4199) MnhB PF04039.13 PVD27683.1 - 5.6 7.3 8.5 7.7 6.8 0.1 4.3 5 0 0 5 5 4 0 Domain related to MnhB subunit of Na+/H+ antiporter Cornifin PF02389.15 PVD27684.1 - 2.2e-17 63.5 63.5 1.1e-05 25.6 14.6 6.4 2 1 6 8 8 8 7 Cornifin (SPRR) family PH_11 PF15413.6 PVD27685.1 - 5 7.6 5.3 8 6.9 1.4 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain DUF5305 PF17231.2 PVD27686.1 - 0.0003 20.3 0.6 0.0003 20.3 0.6 2.9 2 1 1 3 3 3 1 Family of unknown function (DUF5305) Insulin_TMD PF17870.1 PVD27686.1 - 0.0015 18.6 0.2 0.0028 17.7 0.2 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment TMEM154 PF15102.6 PVD27686.1 - 0.0017 18.2 3.9 0.0017 18.2 3.9 4.7 3 1 1 4 4 4 1 TMEM154 protein family DUF4690 PF15756.5 PVD27686.1 - 0.0034 18.0 4.4 0.0034 18.0 4.4 4.5 3 2 0 4 4 4 1 Small Novel Rich in Cartilage PARM PF17061.5 PVD27686.1 - 0.0054 16.9 44.5 0.0054 16.9 44.5 3.3 3 1 0 3 3 3 1 PARM DUF2207 PF09972.9 PVD27686.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 PVD27686.1 - 8.1 6.2 13.2 19 5.0 10.3 2.3 1 1 1 2 2 2 0 Rifin C2-set_2 PF08205.12 PVD27690.1 - 2.2e-06 27.6 0.6 0.065 13.3 0.1 4.1 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 PVD27690.1 - 0.019 15.5 13.4 0.16 12.6 0.1 4.3 3 2 0 3 3 3 0 Immunoglobulin domain C1-set PF07654.15 PVD27690.1 - 0.19 12.1 7.7 0.46 10.9 0.3 3.7 4 0 0 4 4 4 0 Immunoglobulin C1-set domain ig PF00047.25 PVD27691.1 - 3.6e-07 30.3 24.6 0.81 9.9 0.3 9.9 9 2 0 9 9 9 5 Immunoglobulin domain C2-set_2 PF08205.12 PVD27691.1 - 0.0001 22.3 18.2 4.2 7.5 0.1 9.6 10 1 0 10 10 10 3 CD80-like C2-set immunoglobulin domain Imm26 PF15428.6 PVD27691.1 - 0.0078 16.4 0.0 0.84 9.9 0.0 2.5 2 0 0 2 2 2 1 Immunity protein 26 fn3 PF00041.21 PVD27691.1 - 0.077 13.3 0.3 45 4.5 0.0 3.9 4 0 0 4 4 4 0 Fibronectin type III domain DUF4064 PF13273.6 PVD27692.1 - 0.049 13.9 0.1 0.067 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ig_3 PF13927.6 PVD27693.1 - 7.2e-12 45.7 71.6 4.8e-09 36.7 0.1 15.4 13 5 4 17 17 17 5 Immunoglobulin domain I-set PF07679.16 PVD27693.1 - 2.6e-09 37.0 2.1 0.00032 20.7 0.0 5.5 4 1 0 4 4 4 2 Immunoglobulin I-set domain ig PF00047.25 PVD27693.1 - 8.4e-05 22.7 30.3 0.0017 18.5 0.0 9.0 9 1 1 10 10 10 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27693.1 - 0.00029 21.1 0.0 0.00029 21.1 0.0 13.8 10 4 4 16 16 16 2 Immunoglobulin domain Mub_B2 PF17966.1 PVD27693.1 - 2.4 8.9 28.1 5.9 7.7 0.2 7.4 6 2 0 6 6 6 0 Mub B2-like domain MACPF PF01823.19 PVD27694.1 - 4.5e-15 56.3 0.0 6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain RNF111_N PF15303.6 PVD27694.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DDE_Tnp_1_7 PF13843.6 PVD27696.1 - 3.4e-104 348.9 0.0 1.3e-57 195.8 0.0 2.1 2 0 0 2 2 2 2 Transposase IS4 TA_inhibitor PF17574.2 PVD27696.1 - 0.36 10.9 1.7 33 4.6 0.0 2.7 3 0 0 3 3 3 0 Inhibitor of toxin/antitoxin system (Gp4.5) Corona_NS3b PF03053.14 PVD27696.1 - 0.41 10.4 2.2 11 5.7 0.1 2.2 2 0 0 2 2 2 0 ORF3b coronavirus protein Antimicrobial_4 PF08024.11 PVD27696.1 - 7.5 6.7 6.7 2.7 8.1 0.8 2.4 2 0 0 2 2 2 0 Ant antimicrobial peptide DDE_Tnp_1_7 PF13843.6 PVD27697.1 - 5.9e-57 193.6 0.0 8.5e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DUF3969 PF13108.6 PVD27697.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) DDE_Tnp_1_7 PF13843.6 PVD27698.1 - 1.2e-57 195.8 0.0 1.7e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 PVD27698.1 - 4.5 8.2 17.1 2.6 8.9 14.0 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon bZIP_2 PF07716.15 PVD27699.1 - 4.8e-08 33.0 14.3 7.6e-08 32.3 14.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD27699.1 - 0.03 14.4 11.3 0.051 13.7 11.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 PVD27699.1 - 0.22 12.0 8.5 0.39 11.3 8.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 PVD27700.1 - 4.9e-08 32.9 14.6 7.5e-08 32.3 14.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD27700.1 - 0.11 12.6 10.9 0.18 11.9 10.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor Hox9_act PF04617.13 PVD27700.1 - 0.12 13.1 2.4 0.38 11.5 2.4 1.9 1 1 0 1 1 1 0 Hox9 activation region Mx_ML PF17536.2 PVD27701.1 - 0.052 13.3 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal Ig_3 PF13927.6 PVD27702.1 - 2.8e-07 31.0 5.2 0.1 13.2 0.1 3.8 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD27702.1 - 0.0068 16.6 5.0 1.4 9.2 0.3 4.4 4 1 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD27702.1 - 0.024 14.7 7.6 8 6.6 0.4 5.0 4 2 0 4 4 4 0 CD80-like C2-set immunoglobulin domain Glycophorin_A PF01102.18 PVD27702.1 - 0.047 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Acyl-CoA_dh_M PF02770.19 PVD27702.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Ig_3 PF13927.6 PVD27703.1 - 1.8e-17 63.7 46.8 0.24 12.0 0.1 16.1 15 1 0 15 15 15 3 Immunoglobulin domain TMEM154 PF15102.6 PVD27703.1 - 4.5e-11 42.8 6.4 0.0051 16.7 0.2 4.4 4 0 0 4 4 4 3 TMEM154 protein family DUF3377 PF11857.8 PVD27703.1 - 4.6e-08 32.9 7.2 0.0015 18.5 0.7 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF3377) ig PF00047.25 PVD27703.1 - 2.2e-07 31.0 30.0 3.6 7.8 0.0 12.1 10 2 0 10 10 10 1 Immunoglobulin domain V-set PF07686.17 PVD27703.1 - 4.4e-07 30.0 5.1 1.1 9.4 0.0 6.5 6 0 0 6 6 5 1 Immunoglobulin V-set domain DUF4064 PF13273.6 PVD27703.1 - 3.1e-06 27.4 8.1 0.032 14.5 0.6 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF4064) Csm1 PF12539.8 PVD27703.1 - 2e-05 25.2 0.0 14 6.4 0.0 5.3 5 0 0 5 5 5 0 Chromosome segregation protein Csm1/Pcs1 DUF4448 PF14610.6 PVD27703.1 - 2.4e-05 24.2 5.5 0.062 13.1 0.3 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4448) RCR PF12273.8 PVD27703.1 - 0.00037 21.2 0.7 6.4 7.5 0.0 4.9 5 0 0 5 5 4 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 PVD27703.1 - 0.00064 20.5 4.1 3.9 8.4 0.0 4.3 4 0 0 4 4 4 1 Ephrin type-A receptor 2 transmembrane domain Cytochrome-c551 PF10643.9 PVD27703.1 - 0.001 18.7 0.0 0.73 9.4 0.0 2.6 2 0 0 2 2 2 1 Photosystem P840 reaction-centre cytochrome c-551 DUF2207 PF09972.9 PVD27703.1 - 0.0019 17.0 1.5 2.5 6.8 0.0 3.8 4 0 0 4 4 4 1 Predicted membrane protein (DUF2207) C2-set_2 PF08205.12 PVD27703.1 - 0.002 18.2 18.5 5.2 7.2 0.2 12.0 15 1 0 15 15 11 1 CD80-like C2-set immunoglobulin domain Sigma_reg_N PF13800.6 PVD27703.1 - 0.023 15.0 7.9 9.5 6.6 0.0 4.5 4 0 0 4 4 4 0 Sigma factor regulator N-terminal SID-1_RNA_chan PF13965.6 PVD27703.1 - 0.027 12.9 10.7 0.53 8.6 0.9 3.2 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 PVD27703.1 - 0.034 15.1 1.6 4.9 8.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Ctr PF04145.15 PVD27703.1 - 0.039 14.6 0.2 0.45 11.1 0.0 2.6 3 0 0 3 3 3 0 Ctr copper transporter family Plasmod_Pvs28 PF06247.11 PVD27703.1 - 0.04 14.2 4.6 9.9 6.6 0.5 4.2 2 0 0 2 2 2 0 Pvs28 EGF domain ECSCR PF15820.5 PVD27703.1 - 0.059 13.2 10.5 0.97 9.3 0.4 4.2 4 0 0 4 4 3 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 PVD27703.1 - 0.072 13.4 6.8 4.2 7.7 0.1 3.5 4 0 0 4 4 3 0 Orf78 (ac78) FeThRed_A PF02941.15 PVD27703.1 - 0.12 12.5 0.0 8.5 6.6 0.0 3.5 3 0 0 3 3 3 0 Ferredoxin thioredoxin reductase variable alpha chain MLANA PF14991.6 PVD27703.1 - 0.13 12.5 1.2 9.7 6.5 0.0 3.1 4 0 0 4 4 2 0 Protein melan-A DUF5305 PF17231.2 PVD27703.1 - 0.14 11.5 9.7 1.1 8.6 0.3 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5305) DUF5385 PF17359.2 PVD27703.1 - 0.15 11.6 0.9 8.4 5.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) BCHF PF07284.11 PVD27703.1 - 0.21 11.6 1.6 0.25 11.4 0.1 1.9 2 0 0 2 2 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF4519 PF15012.6 PVD27703.1 - 0.21 11.8 10.1 2.4 8.4 2.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FixQ PF05545.11 PVD27703.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.6 4 0 0 4 4 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4808 PF16066.5 PVD27703.1 - 0.26 11.8 0.9 42 4.7 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4808) Chordopox_A13L PF05961.11 PVD27703.1 - 0.26 11.5 1.4 7.2 6.9 0.4 3.5 3 0 0 3 3 3 0 Chordopoxvirus A13L protein DUF4330 PF14221.6 PVD27703.1 - 0.27 11.4 4.4 24 5.1 0.0 3.9 4 0 0 4 4 3 0 Domain of unknown function (DUF4330) DUF485 PF04341.12 PVD27703.1 - 0.38 10.7 7.7 0.88 9.6 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function, DUF485 PMP1_2 PF08114.11 PVD27703.1 - 1.3 8.8 10.7 5.9 6.7 1.0 3.6 3 0 0 3 3 3 0 ATPase proteolipid family DUF4051 PF13260.6 PVD27703.1 - 2.4 8.0 6.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Ig_3 PF13927.6 PVD27704.1 - 1.2e-08 35.5 3.8 0.035 14.7 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 PVD27704.1 - 0.00021 21.3 8.1 6.6 6.9 0.3 5.2 3 2 2 5 5 5 3 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27704.1 - 0.0014 18.8 2.4 1.3 9.3 0.1 3.5 4 0 0 4 4 4 2 Immunoglobulin domain DUF2434 PF10361.9 PVD27704.1 - 0.069 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Ig_4 PF16680.5 PVD27704.1 - 0.45 10.8 2.6 3.7 7.9 0.0 3.1 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 PVD27705.1 - 2.1e-32 111.5 81.5 3.8e-09 37.0 0.9 19.8 18 5 3 21 21 21 7 Immunoglobulin domain I-set PF07679.16 PVD27705.1 - 1.2e-28 99.0 1.1 1.4e-06 28.3 0.0 11.2 12 1 1 13 13 12 4 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27705.1 - 2.3e-21 75.9 67.4 1.1e-06 28.9 0.3 16.3 15 5 5 20 20 19 4 Immunoglobulin domain ig PF00047.25 PVD27705.1 - 1.3e-11 44.5 27.3 0.0066 16.6 0.1 12.3 12 1 0 12 12 12 3 Immunoglobulin domain C2-set_2 PF08205.12 PVD27705.1 - 0.0031 17.5 22.9 4.4 7.4 0.0 10.6 12 0 0 12 12 10 2 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.6 PVD27705.1 - 0.0047 17.8 1.0 0.27 12.2 0.0 2.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 PVD27705.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.7 2 0 0 2 2 2 0 Podoplanin DAP10 PF07213.11 PVD27705.1 - 0.016 15.1 0.0 1.5 8.9 0.0 3.4 2 0 0 2 2 2 0 DAP10 membrane protein Syndecan PF01034.20 PVD27705.1 - 0.037 14.0 6.0 0.28 11.1 0.5 2.6 2 0 0 2 2 2 0 Syndecan domain DUF5518 PF17647.1 PVD27705.1 - 0.082 13.1 8.0 1.2 9.3 1.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5518) Stevor PF17410.2 PVD27705.1 - 0.15 11.6 0.1 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame V-set PF07686.17 PVD27705.1 - 0.24 11.6 9.6 7.7 6.7 0.1 6.3 6 0 0 6 6 5 0 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 PVD27705.1 - 0.31 11.1 0.0 0.31 11.1 0.0 8.9 10 1 1 11 11 10 0 C17orf99 Ig domain EphA2_TM PF14575.6 PVD27706.1 - 3.4e-06 27.8 0.1 0.084 13.8 0.0 3.3 2 1 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain AAA_19 PF13245.6 PVD27706.1 - 0.0034 17.7 0.1 0.7 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain Orthoreo_P10 PF07204.11 PVD27706.1 - 0.016 15.2 0.4 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF2207 PF09972.9 PVD27706.1 - 0.028 13.2 0.1 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 PVD27706.1 - 0.13 12.1 6.3 0.82 9.6 0.1 2.8 1 1 0 2 2 2 0 TMEM154 protein family Shisa PF13908.6 PVD27707.1 - 0.19 12.0 4.0 0.076 13.3 0.4 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 PVD27707.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.1 1 1 1 2 2 2 0 TMEM154 protein family Ig_2 PF13895.6 PVD27708.1 - 1.2e-05 25.5 7.1 0.018 15.3 2.4 2.5 2 0 0 2 2 2 2 Immunoglobulin domain TMEM51 PF15345.6 PVD27708.1 - 0.00065 19.6 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM154 PF15102.6 PVD27708.1 - 0.004 17.1 0.1 0.004 17.1 0.1 2.4 2 1 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 PVD27708.1 - 0.012 15.4 0.5 0.073 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 PVD27708.1 - 0.04 13.5 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4051 PF13260.6 PVD27708.1 - 0.16 11.7 0.5 0.32 10.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) TMEM154 PF15102.6 PVD27709.1 - 0.00038 20.4 0.5 0.0006 19.7 0.1 1.5 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 PVD27709.1 - 0.011 15.6 2.2 0.011 15.6 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 PVD27709.1 - 0.027 15.4 0.7 0.05 14.5 0.7 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 PVD27709.1 - 0.027 14.3 0.6 0.05 13.4 0.6 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 PVD27709.1 - 0.047 14.0 1.3 0.06 13.6 0.2 1.7 2 0 0 2 2 2 0 Orf78 (ac78) Protocadherin PF08374.11 PVD27709.1 - 0.058 13.4 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Protocadherin Alpha_adaptin_C PF02296.16 PVD27709.1 - 0.14 12.3 0.0 0.55 10.4 0.0 1.9 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Shisa PF13908.6 PVD27709.1 - 0.64 10.2 4.3 1.1 9.5 4.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 PVD27709.1 - 5.6 6.8 5.8 2.4 7.9 2.8 1.7 2 0 0 2 2 2 0 Rifin Ig_3 PF13927.6 PVD27710.1 - 3.3e-05 24.4 3.0 0.00038 21.0 3.0 2.7 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD27710.1 - 0.00042 20.4 3.7 0.21 11.8 0.5 3.0 1 1 1 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27710.1 - 0.00053 20.3 2.1 0.0018 18.6 2.1 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27710.1 - 0.00057 19.9 1.9 0.24 11.5 1.9 2.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 PVD27710.1 - 0.0042 17.3 0.1 0.012 15.8 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD27710.1 - 0.076 13.3 2.1 0.53 10.6 0.0 3.0 2 1 1 3 3 3 0 T-cell surface glycoprotein CD3 delta chain UPF0223 PF05256.12 PVD27710.1 - 0.12 12.8 1.2 2.5 8.5 0.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0223) C2-set_2 PF08205.12 PVD27710.1 - 0.12 12.5 4.7 0.099 12.7 1.6 2.4 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.6 PVD27711.1 - 0.04 13.8 0.2 0.097 12.6 0.1 1.7 1 1 1 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.16 PVD27712.1 - 0.0009 18.1 0.4 0.0018 17.1 0.1 1.6 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF3377 PF11857.8 PVD27712.1 - 0.003 17.5 1.1 0.0067 16.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Amnionless PF14828.6 PVD27712.1 - 0.0065 15.4 0.2 0.0097 14.8 0.1 1.3 1 1 0 1 1 1 1 Amnionless SIT PF15330.6 PVD27712.1 - 0.027 14.9 0.0 0.16 12.4 0.0 2.3 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT PIRT PF15099.6 PVD27712.1 - 0.036 13.6 0.1 0.083 12.5 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family EphA2_TM PF14575.6 PVD27712.1 - 0.045 14.6 0.5 0.12 13.3 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SID-1_RNA_chan PF13965.6 PVD27712.1 - 0.07 11.5 0.1 0.094 11.1 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM154 PF15102.6 PVD27712.1 - 0.075 12.9 1.5 0.078 12.9 0.2 1.7 2 0 0 2 2 2 0 TMEM154 protein family Stevor PF17410.2 PVD27712.1 - 0.084 12.4 3.1 0.072 12.6 0.5 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 PVD27712.1 - 0.13 12.4 3.7 0.23 11.5 3.7 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ASFV_J13L PF05568.11 PVD27712.1 - 1.2 8.8 6.2 0.25 11.1 2.6 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein Orf78 PF06024.12 PVD27712.1 - 2.4 8.5 4.1 0.9 9.9 0.1 2.1 2 1 0 2 2 2 0 Orf78 (ac78) zf-H2C2_2 PF13465.6 PVD27713.1 - 1.4e-69 227.6 89.4 6.6e-08 32.6 1.6 16.1 15 0 0 15 15 15 11 Zinc-finger double domain Myb_DNA-bind_5 PF13873.6 PVD27713.1 - 1.5e-55 185.2 31.5 1.1e-14 54.2 5.1 5.7 5 0 0 5 5 5 5 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.26 PVD27713.1 - 8.4e-44 145.6 106.0 5.3e-05 23.5 0.4 15.0 14 0 0 14 14 14 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27713.1 - 2e-31 106.0 107.6 0.0025 18.5 0.4 15.7 15 0 0 15 15 14 12 C2H2-type zinc finger Myb_DNA-bind_4 PF13837.6 PVD27713.1 - 1e-16 61.1 25.5 0.002 18.4 1.7 5.8 5 0 0 5 5 5 5 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD27713.1 - 3e-08 33.9 24.2 0.098 13.0 0.5 5.7 5 0 0 5 5 5 4 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3268 PF11672.8 PVD27713.1 - 0.0072 16.6 0.1 0.0072 16.6 0.1 6.8 5 2 4 9 9 9 4 zinc-finger-containing domain zf-met PF12874.7 PVD27713.1 - 0.019 15.4 70.6 0.25 11.8 0.5 13.3 14 0 0 14 14 14 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD27713.1 - 0.021 14.6 0.0 0.021 14.6 0.0 10.3 12 0 0 12 12 10 0 zinc-finger C2H2-type Myb_DNA-binding PF00249.31 PVD27713.1 - 1.4 9.2 11.8 33 4.8 0.6 5.3 5 0 0 5 5 5 0 Myb-like DNA-binding domain zf-C2H2_6 PF13912.6 PVD27713.1 - 3.8 7.6 90.9 0.038 14.0 0.8 12.8 13 0 0 13 13 11 0 C2H2-type zinc finger HTH_32 PF13565.6 PVD27713.1 - 5.2 7.7 9.3 28 5.4 0.8 4.0 4 0 0 4 4 4 0 Homeodomain-like domain ALMT PF11744.8 PVD27717.1 - 9.2 5.0 6.1 11 4.7 6.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ig_3 PF13927.6 PVD27720.1 - 1.2e-84 278.9 26.8 1.8e-12 47.7 0.0 9.7 10 0 0 10 10 9 9 Immunoglobulin domain I-set PF07679.16 PVD27720.1 - 1.4e-70 233.4 9.0 1.1e-13 51.1 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27720.1 - 7.1e-67 221.7 20.7 1.1e-09 38.5 0.0 9.3 9 0 0 9 9 9 9 Immunoglobulin domain C2-set_2 PF08205.12 PVD27720.1 - 8e-48 160.5 5.0 2.1e-10 40.5 0.6 8.5 8 0 0 8 8 8 6 CD80-like C2-set immunoglobulin domain ig PF00047.25 PVD27720.1 - 2.2e-40 136.7 17.0 2.8e-06 27.4 0.3 9.6 9 1 0 9 9 9 7 Immunoglobulin domain C1-set PF07654.15 PVD27720.1 - 2.3e-18 66.4 10.6 0.00013 22.2 0.0 8.4 8 1 0 8 8 8 4 Immunoglobulin C1-set domain fn3 PF00041.21 PVD27720.1 - 5e-13 49.2 0.0 3.7e-12 46.4 0.0 2.7 2 0 0 2 2 1 1 Fibronectin type III domain V-set PF07686.17 PVD27720.1 - 1.6e-12 47.5 29.2 0.027 14.6 0.1 11.7 8 6 2 11 11 11 5 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD27720.1 - 9.5e-09 35.5 5.5 17 5.9 0.0 9.2 8 3 0 8 8 8 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD27720.1 - 5.5e-08 33.0 9.3 6.1 7.2 0.1 9.9 8 4 0 8 8 8 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD27720.1 - 0.0012 18.9 0.3 5.7 7.1 0.0 4.7 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD27720.1 - 0.02 15.1 2.0 3.8 7.8 0.0 4.9 6 0 0 6 6 5 0 Immunoglobulin C2-set domain DUF5060 PF16586.5 PVD27720.1 - 0.038 14.4 0.1 0.15 12.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) Herpes_gp2 PF05955.11 PVD27720.1 - 0.072 12.6 0.7 0.24 10.9 0.2 2.0 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Collar PF07484.12 PVD27721.1 - 0.032 14.2 1.5 2.6 8.1 0.1 2.8 2 1 0 2 2 2 0 Phage Tail Collar Domain RNA_pol_Rpb8 PF03870.15 PVD27723.1 - 6.4e-19 68.5 0.0 6.7e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Dor1 PF04124.12 PVD27724.1 - 4.3e-96 321.5 0.9 5.8e-96 321.1 0.9 1.2 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 PVD27724.1 - 0.47 9.7 4.3 1.1 8.5 0.9 2.5 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Ig_3 PF13927.6 PVD27725.1 - 1e-41 141.4 0.1 3.6e-13 49.9 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD27725.1 - 1.9e-36 124.0 0.0 4.8e-14 52.2 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27725.1 - 1.4e-31 108.6 0.0 9.2e-12 45.1 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 PVD27725.1 - 2.3e-25 88.6 2.0 5.3e-07 29.7 0.0 5.3 5 1 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 PVD27725.1 - 8.5e-22 77.3 0.0 3.5e-13 49.7 0.1 2.8 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 PVD27725.1 - 2.5e-16 59.8 4.3 0.0073 16.5 0.0 7.4 4 3 2 6 6 6 4 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD27725.1 - 1.2e-09 38.5 0.0 0.048 14.1 0.0 4.6 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD27725.1 - 9.9e-08 32.1 0.0 0.02 15.1 0.0 4.2 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD27725.1 - 3.8e-07 30.1 0.1 0.004 17.2 0.0 3.9 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD27725.1 - 4.9e-07 29.2 0.0 0.41 10.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD27725.1 - 2.9e-06 27.3 0.0 0.48 10.5 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 PVD27725.1 - 3.3e-05 22.8 0.2 0.02 13.7 0.0 3.6 3 1 0 3 3 3 1 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.12 PVD27725.1 - 0.0029 17.6 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family TNFR_16_TM PF18422.1 PVD27725.1 - 0.0043 17.0 1.6 0.0077 16.2 1.6 1.3 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain MAP17 PF15807.5 PVD27725.1 - 0.0044 17.2 0.4 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PRIMA1 PF16101.5 PVD27725.1 - 0.0047 17.0 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 PVD27725.1 - 0.02 15.7 1.1 0.025 15.4 0.0 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 PVD27725.1 - 0.083 13.2 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 LST-1 protein CKS PF01111.19 PVD27732.1 - 2.2e-38 130.4 0.8 2.8e-38 130.0 0.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sdh_cyt PF01127.22 PVD27733.1 - 1.9e-17 63.4 4.6 2.2e-17 63.2 4.6 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1143 PF06608.11 PVD27734.1 - 2e-18 66.8 7.4 2.2e-13 50.5 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1143) DUF4819 PF16090.5 PVD27735.1 - 3.9e-19 68.5 0.0 7.9e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4819) DUF4537 PF15057.6 PVD27735.1 - 1.6e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) HMG_box PF00505.19 PVD27736.1 - 3.9e-16 59.2 2.3 9.9e-16 57.9 2.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD27736.1 - 5e-07 30.2 1.0 1.4e-06 28.8 1.0 1.8 1 0 0 1 1 1 1 HMG-box domain Nicastrin PF05450.15 PVD27737.1 - 3.8e-54 183.6 0.4 5.3e-54 183.1 0.4 1.2 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 PVD27737.1 - 5.7e-54 182.6 0.0 1.5e-53 181.2 0.0 1.8 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 PVD27737.1 - 9e-08 32.0 0.1 1.5e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nrap_D5 PF17406.2 PVD27737.1 - 0.079 12.7 0.0 1 9.1 0.0 2.6 3 0 0 3 3 3 0 Nrap protein PAP/OAS1-like domain 5 7tm_1 PF00001.21 PVD27738.1 - 2.7e-18 66.3 0.2 2.5e-07 30.3 0.0 3.1 3 0 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) PalH PF08733.10 PVD27738.1 - 0.0099 14.9 5.8 0.17 10.9 0.9 3.1 3 0 0 3 3 3 2 PalH/RIM21 Saf_2TM PF18303.1 PVD27738.1 - 0.19 11.3 0.1 0.58 9.7 0.0 1.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF485 PF04341.12 PVD27738.1 - 0.26 11.2 12.4 0.1 12.6 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF485 zf-LITAF-like PF10601.9 PVD27738.1 - 8.1 6.8 7.7 14 6.1 0.6 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.21 PVD27739.1 - 1.4e-07 31.1 9.0 7.3e-06 25.5 0.1 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD27739.1 - 0.11 11.8 5.0 0.67 9.2 0.3 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4199 PF13858.6 PVD27739.1 - 0.32 11.4 1.9 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF4692 PF15763.5 PVD27739.1 - 1.7 9.1 6.0 4.5 7.7 0.6 2.4 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) 7tm_1 PF00001.21 PVD27741.1 - 2.5e-20 72.9 1.3 3.9e-20 72.3 1.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 PVD27741.1 - 0.0011 19.2 2.3 0.82 10.0 0.0 3.8 4 0 0 4 4 4 1 Orf78 (ac78) DUF4338 PF14236.6 PVD27741.1 - 0.028 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) DUF4922 PF16269.5 PVD27741.1 - 0.072 12.9 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) 7tm_1 PF00001.21 PVD27742.1 - 1.4e-15 57.3 1.9 1.8e-15 57.0 1.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD27743.1 - 1.5e-18 67.1 7.6 2.1e-18 66.6 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD27743.1 - 1.3e-06 28.0 10.2 2.1e-06 27.3 10.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD27743.1 - 0.011 15.0 10.3 0.019 14.3 10.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2633 PF11119.8 PVD27743.1 - 0.015 15.2 0.3 0.039 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) 7tm_4 PF13853.6 PVD27743.1 - 0.027 14.2 11.2 0.06 13.1 11.3 1.6 1 1 0 1 1 1 0 Olfactory receptor INSIG PF07281.12 PVD27743.1 - 0.06 13.0 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) SPC25 PF06703.11 PVD27743.1 - 0.11 12.3 0.2 0.27 11.0 0.1 1.7 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Syndecan PF01034.20 PVD27743.1 - 2.4 8.2 5.3 3.5 7.6 0.3 3.0 3 0 0 3 3 3 0 Syndecan domain 7tm_1 PF00001.21 PVD27744.1 - 2.3e-17 63.2 8.6 2.4e-16 59.9 0.1 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD27745.1 - 2.4e-20 73.0 10.9 1.4e-17 63.9 2.4 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD27745.1 - 0.00092 18.7 20.2 0.0021 17.5 12.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2208 PF09973.9 PVD27745.1 - 0.16 11.5 1.1 0.41 10.2 1.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF1772 PF08592.11 PVD27745.1 - 2.7 8.3 6.1 1.5 9.1 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.21 PVD27746.1 - 4.1 6.6 5.6 36 3.6 0.0 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD27747.1 - 2.2e-10 40.3 0.1 5.1e-05 22.7 0.1 2.0 1 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Innexin PF00876.18 PVD27747.1 - 0.05 12.9 0.0 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Innexin STE3 PF02076.15 PVD27747.1 - 0.061 12.5 2.5 0.98 8.6 0.0 2.8 3 0 0 3 3 3 0 Pheromone A receptor Saf_2TM PF18303.1 PVD27747.1 - 0.08 12.5 2.1 12 5.5 0.2 2.9 3 1 0 3 3 3 0 SAVED-fused 2TM effector domain zf-LITAF-like PF10601.9 PVD27747.1 - 0.21 11.9 2.6 7.2 7.0 0.2 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2613 PF11021.8 PVD27747.1 - 3.5 7.8 4.7 53 4.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) 7tm_1 PF00001.21 PVD27748.1 - 0.00032 20.1 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD27749.1 - 9.1e-07 28.5 0.0 9.3e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD27750.1 - 1.4e-22 80.3 7.4 2.6e-22 79.4 7.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UbiA PF01040.18 PVD27750.1 - 0.029 13.7 0.2 1.5 8.1 0.1 2.4 2 1 0 2 2 2 0 UbiA prenyltransferase family PRA1 PF03208.19 PVD27750.1 - 0.11 12.2 6.9 0.45 10.1 0.4 3.3 3 0 0 3 3 3 0 PRA1 family protein DUF4834 PF16118.5 PVD27750.1 - 0.39 11.7 0.1 0.39 11.7 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 PVD27750.1 - 0.49 10.6 0.0 0.49 10.6 0.0 2.8 3 0 0 3 3 3 0 HemY protein N-terminus Shisa PF13908.6 PVD27750.1 - 0.53 10.5 11.1 2.5 8.3 0.1 3.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator RFX_DNA_binding PF02257.15 PVD27751.1 - 1.1e-33 115.7 0.1 3.4e-33 114.1 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 PVD27751.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like Synaptobrevin PF00957.21 PVD27751.1 - 0.027 14.2 0.3 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF900 PF05990.12 PVD27751.1 - 0.14 11.6 0.1 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4064 PF13273.6 PVD27752.1 - 0.05 13.9 0.7 0.092 13.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) IspA PF04279.15 PVD27752.1 - 0.06 13.5 0.1 0.091 12.9 0.1 1.2 1 0 0 1 1 1 0 Intracellular septation protein A Ldl_recept_a PF00057.18 PVD27754.1 - 2.1e-17 63.0 26.4 7.6e-10 38.9 10.8 2.5 2 1 1 3 3 3 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD27755.1 - 2.2e-09 37.4 15.1 3.4e-09 36.8 15.1 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A NHL PF01436.21 PVD27756.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.9 2 0 0 2 2 2 0 NHL repeat Ldl_recept_a PF00057.18 PVD27757.1 - 5.6e-19 68.1 37.0 5.4e-10 39.3 10.9 3.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD27758.1 - 2.6e-29 101.1 43.3 3.7e-10 39.8 9.5 3.1 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DUF4051 PF13260.6 PVD27758.1 - 0.14 11.9 0.7 0.29 10.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Pkinase PF00069.25 PVD27761.1 - 3.9e-74 249.4 0.0 5.5e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD27761.1 - 1.2e-41 142.7 0.0 1.8e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD27761.1 - 8.8e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD27761.1 - 0.00027 20.0 0.0 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain ETF PF01012.21 PVD27762.1 - 5.2e-48 163.3 0.6 8e-48 162.7 0.6 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HARE-HTH PF05066.13 PVD27762.1 - 0.0021 18.4 0.4 1.9 9.0 0.0 3.4 2 1 1 3 3 3 1 HB1, ASXL, restriction endonuclease HTH domain HTH_Crp_2 PF13545.6 PVD27762.1 - 0.042 13.8 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain DUF2288 PF10052.9 PVD27762.1 - 0.049 13.7 0.2 0.091 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Mnd1 PF03962.15 PVD27762.1 - 0.21 11.9 1.2 2.3 8.6 0.2 2.6 2 0 0 2 2 2 0 Mnd1 HTH domain Pkinase PF00069.25 PVD27764.1 - 6.7e-74 248.6 0.0 1e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD27764.1 - 1.4e-41 142.5 0.0 2.2e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD27764.1 - 4.9e-06 26.1 0.0 8.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD27764.1 - 0.00097 18.5 1.6 0.0025 17.2 1.6 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD27764.1 - 0.0025 16.8 0.1 0.0025 16.8 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain KA1 PF02149.19 PVD27764.1 - 0.027 14.3 0.0 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 Kinase associated domain 1 Phasin PF05597.11 PVD27764.1 - 0.13 12.3 0.0 6.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlxA PF14282.6 PVD27764.1 - 0.67 10.0 8.9 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 FlxA-like protein PriC PF07445.12 PVD27764.1 - 2.4 8.1 11.7 6.3 6.7 0.7 3.0 3 0 0 3 3 3 0 Primosomal replication protein priC TSP_1 PF00090.19 PVD27765.1 - 8.3e-17 61.1 35.5 5.3e-09 36.2 15.4 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain I-set PF07679.16 PVD27765.1 - 4.4e-11 42.7 0.2 2.3e-05 24.4 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27765.1 - 9.7e-11 42.1 7.4 7.7e-06 26.4 0.1 4.4 3 1 1 4 4 4 2 Immunoglobulin domain ig PF00047.25 PVD27765.1 - 5.9e-06 26.4 0.2 5.9e-06 26.4 0.2 4.4 5 0 0 5 5 5 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27765.1 - 0.00023 21.4 0.1 0.00023 21.4 0.1 5.2 6 1 0 6 6 5 1 Immunoglobulin domain DUF5385 PF17359.2 PVD27765.1 - 0.00029 20.5 0.4 0.00052 19.6 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5385) EVC2_like PF12297.8 PVD27765.1 - 0.0095 14.7 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein Myc_target_1 PF15179.6 PVD27765.1 - 0.014 15.3 0.5 0.057 13.3 0.1 2.1 2 0 0 2 2 2 0 Myc target protein 1 EphA2_TM PF14575.6 PVD27765.1 - 0.029 15.2 0.0 0.075 13.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.6 PVD27765.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4330) Sulf_transp PF04143.14 PVD27765.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Sulphur transport DUF4328 PF14219.6 PVD27765.1 - 0.054 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF5305 PF17231.2 PVD27765.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MFS_Mycoplasma PF07672.13 PVD27765.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Orf78 PF06024.12 PVD27765.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Flagellin_D3 PF08884.11 PVD27765.1 - 0.27 11.6 4.5 6.7 7.2 0.1 3.1 2 1 0 2 2 2 0 Flagellin D3 domain TMEM154 PF15102.6 PVD27765.1 - 2.8 7.8 4.8 0.89 9.5 0.4 2.2 1 1 1 2 2 2 0 TMEM154 protein family TSP_1 PF00090.19 PVD27766.1 - 2.4e-10 40.5 11.0 6e-10 39.2 11.0 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain TSP_1 PF00090.19 PVD27767.1 - 2.8e-20 72.3 40.9 2.2e-10 40.6 15.8 3.3 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 PVD27767.1 - 6.9e-05 23.4 1.2 0.00011 22.8 0.8 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27767.1 - 0.00017 21.8 0.2 0.00017 21.8 0.2 2.3 2 2 0 3 3 3 1 Immunoglobulin domain DUF4964 PF16334.5 PVD27767.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) SRCR PF00530.18 PVD27768.1 - 3.1e-22 79.0 8.5 2e-12 47.5 0.4 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain I-set PF07679.16 PVD27768.1 - 4.2e-10 39.5 0.0 8.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27768.1 - 1.2e-08 35.1 0.1 3.5e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD27768.1 - 2.5e-08 34.0 0.1 5.2e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27768.1 - 7.2e-08 32.9 0.1 2.3e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD27768.1 - 0.0013 18.9 4.2 0.12 12.5 1.0 3.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain EF-hand_5 PF13202.6 PVD27769.1 - 1.3e-05 24.5 2.2 0.0074 15.7 0.1 3.9 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 PVD27769.1 - 8.2e-05 23.0 6.6 0.046 14.2 0.5 3.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD27769.1 - 0.00014 21.6 7.7 0.016 15.1 0.2 3.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD27769.1 - 0.00017 21.3 11.2 0.055 13.4 0.6 3.6 3 2 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PVD27769.1 - 0.0077 15.7 11.9 0.06 12.9 0.1 3.7 4 0 0 4 4 4 2 EF hand Caleosin PF05042.13 PVD27769.1 - 0.068 13.1 0.6 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 Caleosin related protein Claudin_2 PF13903.6 PVD27771.1 - 8.6e-12 45.2 11.5 1.5e-11 44.4 11.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD27771.1 - 2.8e-06 27.6 8.5 4.6e-06 26.9 8.5 1.3 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 PVD27771.1 - 4.1e-06 26.8 12.3 6.8e-06 26.0 12.3 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD27771.1 - 8.8e-05 22.5 8.8 0.00038 20.5 8.8 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like MgtE PF01769.16 PVD27771.1 - 0.17 12.2 10.5 0.38 11.1 0.3 2.4 2 1 0 2 2 2 0 Divalent cation transporter Clc-like PF07062.12 PVD27771.1 - 0.6 9.5 17.2 1.2e+02 2.0 17.2 2.7 1 1 0 1 1 1 0 Clc-like DUF4199 PF13858.6 PVD27771.1 - 9.3 6.6 9.1 5.8 7.3 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) ABC_tran PF00005.27 PVD27772.1 - 8.6e-22 78.1 0.0 1.7e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PVD27772.1 - 4e-17 62.4 1.9 6.9e-17 61.6 1.9 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PVD27772.1 - 1.3e-13 51.4 0.5 9.4e-10 38.8 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PVD27772.1 - 1.7e-10 40.7 1.7 2.7e-10 40.0 1.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter SMC_N PF02463.19 PVD27772.1 - 0.013 15.0 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 PVD27772.1 - 0.017 14.5 0.3 4.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PVD27772.1 - 0.046 13.6 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 PVD27772.1 - 0.059 13.8 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0182 PF03699.13 PVD27772.1 - 0.098 10.8 0.1 0.13 10.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) AAA_33 PF13671.6 PVD27772.1 - 0.13 12.4 0.2 2.4 8.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PVD27772.1 - 0.22 11.4 0.4 0.47 10.3 0.4 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Polysacc_syn_2C PF08485.10 PVD27773.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal SnAPC_2_like PF11035.8 PVD27774.1 - 1.8e-19 71.1 0.6 1.1e-08 35.6 0.0 3.2 1 1 1 3 3 3 3 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Myb_DNA-binding PF00249.31 PVD27774.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain SPATA1_C PF15743.5 PVD27774.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus DUF262 PF03235.14 PVD27774.1 - 0.093 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 Pkinase PF00069.25 PVD27775.1 - 3.7e-68 229.8 0.0 4.3e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD27775.1 - 1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD27775.1 - 6.9e-07 28.9 0.0 4.3e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 PVD27775.1 - 0.00098 19.1 0.0 0.008 16.1 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD27775.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PVD27775.1 - 0.047 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_8 PF13855.6 PVD27776.1 - 2.5e-22 78.4 26.8 4.5e-09 35.9 1.9 5.3 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PVD27776.1 - 8.8e-19 67.3 36.6 9.3e-06 25.9 1.1 5.9 2 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD27776.1 - 4.1e-05 23.1 16.2 0.038 13.5 0.2 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PVD27776.1 - 4.5e-05 23.4 33.0 3 8.7 1.0 8.7 7 2 0 7 7 7 3 Leucine Rich Repeat DNA_ligase_ZBD PF03119.16 PVD27776.1 - 1.2 9.3 3.9 1.7 8.8 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain HAUS5 PF14817.6 PVD27777.1 - 1e-49 169.9 30.3 2.7e-26 92.5 4.0 2.0 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 5 Bacillus_HBL PF05791.11 PVD27777.1 - 0.024 14.5 5.8 6.7 6.5 0.1 3.7 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1054 PF06335.12 PVD27777.1 - 0.066 13.1 6.8 0.26 11.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1054) T4_Rnl2_C PF18043.1 PVD27777.1 - 0.37 11.0 0.1 0.37 11.0 0.1 2.5 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal PTH2 PF01981.16 PVD27777.1 - 4 7.8 6.2 30 4.9 0.4 3.1 3 0 0 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 Csm2_III-A PF03750.13 PVD27777.1 - 5.5 7.9 11.2 0.75 10.7 0.5 3.7 2 1 2 4 4 4 0 Csm2 Type III-A LRR_4 PF12799.7 PVD27778.1 - 4.3e-08 33.3 11.2 0.021 15.3 0.0 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD27778.1 - 1.4e-07 31.1 1.3 0.002 17.7 0.0 4.0 2 1 2 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.6 PVD27778.1 - 2e-06 27.4 3.9 0.035 13.9 0.0 4.3 3 1 1 4 4 4 2 Leucine rich repeat ubiquitin PF00240.23 PVD27778.1 - 3.8e-05 23.4 0.0 9.2e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PVD27778.1 - 0.0054 17.2 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.6 PVD27778.1 - 0.0097 15.9 0.6 15 5.9 0.0 3.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 PVD27778.1 - 0.18 12.5 0.9 56 4.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Pex19 PF04614.12 PVD27779.1 - 9.4e-43 146.7 14.6 9.4e-43 146.7 14.6 2.6 2 1 0 2 2 2 1 Pex19 protein family DUF3450 PF11932.8 PVD27779.1 - 0.038 13.3 0.2 0.038 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FliT PF05400.13 PVD27779.1 - 0.08 13.8 8.4 7.7 7.4 0.3 3.5 3 1 0 3 3 3 0 Flagellar protein FliT DUF4487 PF14868.6 PVD27779.1 - 0.09 11.6 0.2 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) mTERF PF02536.14 PVD27779.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 mTERF DUF445 PF04286.12 PVD27779.1 - 0.66 9.7 2.6 2.6 7.7 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) zf-C2H2 PF00096.26 PVD27780.1 - 1.6e-21 75.5 65.7 4.1e-06 26.9 1.0 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD27780.1 - 6.4e-16 57.7 60.7 0.00019 22.0 0.4 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD27780.1 - 6.1e-14 51.7 63.7 0.00012 22.3 4.4 9.1 9 0 0 9 9 9 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 PVD27780.1 - 1.8e-06 27.6 34.0 0.00094 18.9 0.5 6.0 6 0 0 6 6 6 3 C2H2-type zinc-finger domain GAGA PF09237.11 PVD27780.1 - 4.8e-05 23.1 6.7 0.055 13.3 0.1 3.8 2 1 1 3 3 3 2 GAGA factor zf-met PF12874.7 PVD27780.1 - 0.00047 20.5 32.0 1.7 9.1 0.2 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD27780.1 - 0.0065 16.2 0.1 0.0065 16.2 0.1 7.2 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD27780.1 - 0.0068 16.4 0.4 0.0068 16.4 0.4 7.5 6 1 1 7 7 7 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD27780.1 - 0.38 11.4 29.0 1.9 9.2 0.5 5.4 1 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 PVD27780.1 - 1 10.2 24.9 0.66 10.8 0.6 4.2 2 1 3 5 5 5 0 zinc-ribbon family zf-C2H2_8 PF15909.5 PVD27780.1 - 1.1 9.6 30.3 0.075 13.3 6.8 4.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon BolA PF01722.18 PVD27780.1 - 1.5 9.2 5.0 1.2 9.5 0.1 3.1 2 1 1 3 3 3 0 BolA-like protein zf-Dof PF02701.15 PVD27780.1 - 2.3 8.4 18.1 1.3 9.3 3.7 4.0 3 1 1 4 4 4 0 Dof domain, zinc finger zf-dskA_traR PF01258.17 PVD27780.1 - 2.5 8.1 6.9 3.3 7.7 0.0 3.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.10 PVD27780.1 - 3 8.1 27.7 0.79 9.9 0.1 5.3 4 1 2 6 6 6 0 Zinc ribbon domain Sulfotransfer_1 PF00685.27 PVD27781.1 - 1.7e-36 126.1 0.1 2.6e-35 122.2 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain BTB PF00651.31 PVD27781.1 - 3.1e-17 62.8 0.0 1.2e-15 57.7 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Sulfotransfer_3 PF13469.6 PVD27781.1 - 2.6e-07 31.3 1.5 1.9e-06 28.4 0.1 2.6 3 0 0 3 3 3 1 Sulfotransferase family PUB_1 PF18486.1 PVD27781.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain CarboxypepD_reg PF13620.6 PVD27782.1 - 1e-46 157.1 6.2 1.9e-07 31.3 0.2 9.8 9 0 0 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 PVD27782.1 - 1.5e-20 73.5 10.5 0.0096 16.1 0.1 9.1 9 0 0 9 9 9 5 SdrD B-like domain DUF2012 PF09430.10 PVD27782.1 - 4.2e-20 72.1 0.0 0.0015 18.6 0.0 7.8 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 PVD27782.1 - 5.8e-18 64.7 13.1 8.1e-06 25.8 0.2 8.7 8 0 0 8 8 8 3 CarboxypepD_reg-like domain SpaA PF17802.1 PVD27782.1 - 4.1e-11 43.0 4.7 0.97 9.8 0.0 8.0 6 2 1 7 7 7 3 Prealbumin-like fold domain fn3_3 PF14686.6 PVD27782.1 - 1.1e-09 38.0 7.4 0.00044 20.0 0.1 7.0 8 0 0 8 8 8 2 Polysaccharide lyase family 4, domain II DUF2846 PF11008.8 PVD27782.1 - 0.00039 20.4 2.5 1.4 9.0 0.0 5.4 5 0 0 5 5 5 1 Protein of unknown function (DUF2846) MetallophosN PF16371.5 PVD27782.1 - 0.0046 17.2 3.9 0.087 13.1 0.1 4.6 5 0 0 5 5 5 1 N terminal of Calcineurin-like phosphoesterase Y_Y_Y PF07495.13 PVD27782.1 - 0.01 15.8 3.9 28 4.8 0.0 6.0 7 0 0 7 7 7 0 Y_Y_Y domain fn3 PF00041.21 PVD27782.1 - 0.099 13.0 0.1 4.2 7.8 0.0 3.6 4 0 0 4 4 3 0 Fibronectin type III domain EMP24_GP25L PF01105.24 PVD27782.1 - 0.12 12.3 0.6 43 4.0 0.1 4.2 3 1 1 4 4 4 0 emp24/gp25L/p24 family/GOLD Big_1 PF02369.16 PVD27782.1 - 2.4 8.2 7.0 17 5.5 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 1) XRCC1_N PF01834.16 PVD27783.1 - 6e-54 182.1 0.7 1e-53 181.3 0.1 1.7 2 0 0 2 2 2 1 XRCC1 N terminal domain BRCT_2 PF16589.5 PVD27783.1 - 9.2e-21 74.1 0.0 1.8e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PVD27783.1 - 5.7e-18 65.1 0.0 1.5e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PVD27783.1 - 3.4e-09 36.5 0.0 4.6e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 PVD27783.1 - 1e-07 32.2 0.0 5.5e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Hormone_recep PF00104.30 PVD27784.1 - 0.00028 20.5 0.3 0.00037 20.1 0.3 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LytTR PF04397.15 PVD27784.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 LytTr DNA-binding domain DUF4393 PF14337.6 PVD27784.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) zf-C4 PF00105.18 PVD27785.1 - 1.6e-19 70.2 15.1 3.2e-19 69.1 15.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD27785.1 - 3.2e-08 33.4 0.1 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF4371 PF14291.6 PVD27787.1 - 0.00061 19.5 0.1 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) SH3_2 PF07653.17 PVD27787.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF5448 PF17526.2 PVD27787.1 - 0.029 14.5 0.6 0.42 10.8 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5448) Ig_3 PF13927.6 PVD27788.1 - 2.4e-22 79.3 22.2 5.8e-09 36.4 1.9 6.9 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 PVD27788.1 - 1.3e-16 60.5 1.0 0.0038 17.3 0.0 7.3 6 1 0 6 6 6 4 Immunoglobulin I-set domain ig PF00047.25 PVD27788.1 - 2.9e-14 53.0 20.5 0.0025 17.9 1.4 6.9 6 1 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 PVD27788.1 - 4.3e-14 52.6 28.8 0.0015 18.9 0.0 6.7 6 1 1 7 7 7 5 Immunoglobulin domain C2-set_2 PF08205.12 PVD27788.1 - 1.8e-09 37.5 17.0 0.013 15.6 0.3 5.2 4 2 0 4 4 4 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27788.1 - 7.3e-06 26.1 11.3 0.71 10.1 0.2 6.7 6 2 0 7 7 7 2 Immunoglobulin V-set domain EphA2_TM PF14575.6 PVD27788.1 - 0.025 15.5 2.1 0.077 13.9 0.8 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 PVD27788.1 - 0.088 12.7 0.5 0.14 12.0 0.5 1.2 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 PVD27788.1 - 0.15 11.9 3.9 0.32 10.8 3.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 PVD27788.1 - 0.2 11.6 1.3 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 Protocadherin Ig_3 PF13927.6 PVD27789.1 - 1.1e-24 86.8 30.1 2.4e-05 24.9 0.6 9.9 8 1 1 9 9 9 6 Immunoglobulin domain Ig_2 PF13895.6 PVD27789.1 - 8.4e-19 67.7 46.8 9.8e-06 25.8 0.8 9.8 10 1 0 10 10 10 5 Immunoglobulin domain I-set PF07679.16 PVD27789.1 - 8.8e-17 61.0 6.2 0.00017 21.6 0.0 7.3 7 0 0 7 7 6 3 Immunoglobulin I-set domain ig PF00047.25 PVD27789.1 - 8.8e-11 41.8 24.1 0.0026 17.9 0.1 10.6 10 1 2 12 12 10 3 Immunoglobulin domain DUF4448 PF14610.6 PVD27789.1 - 0.00012 21.9 0.1 0.22 11.3 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF4448) TMEM154 PF15102.6 PVD27789.1 - 0.00031 20.7 2.5 0.62 10.0 0.0 2.9 2 0 0 2 2 2 2 TMEM154 protein family C2-set_2 PF08205.12 PVD27789.1 - 0.00061 19.8 19.0 4.8 7.3 0.0 8.2 8 1 0 8 8 8 1 CD80-like C2-set immunoglobulin domain DUF5305 PF17231.2 PVD27789.1 - 0.0036 16.7 4.4 0.27 10.6 1.4 3.2 3 0 0 3 3 3 1 Family of unknown function (DUF5305) HemY_N PF07219.13 PVD27789.1 - 0.0055 16.9 2.6 0.4 10.9 0.2 2.3 2 0 0 2 2 2 1 HemY protein N-terminus Nefa_Nip30_N PF10187.9 PVD27789.1 - 0.0064 16.8 2.8 2.2 8.7 0.2 2.3 2 0 0 2 2 2 2 N-terminal domain of NEFA-interacting nuclear protein NIP30 Stevor PF17410.2 PVD27789.1 - 0.013 15.1 1.8 1.1 8.8 0.7 2.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 PVD27789.1 - 0.03 14.6 0.8 6.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Cadherin_C_2 PF16492.5 PVD27789.1 - 0.051 14.3 3.3 2.3 9.0 0.1 3.5 3 0 0 3 3 2 0 Cadherin cytoplasmic C-terminal DUF2207 PF09972.9 PVD27789.1 - 0.078 11.7 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) V-set PF07686.17 PVD27789.1 - 0.089 13.0 11.8 13 6.0 0.0 7.1 7 1 1 8 8 8 0 Immunoglobulin V-set domain LAX PF15681.5 PVD27789.1 - 0.1 11.4 11.1 0.022 13.6 1.9 2.5 2 0 0 2 2 2 0 Lymphocyte activation family X DUF4307 PF14155.6 PVD27789.1 - 0.18 11.6 3.0 6.7 6.6 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) EphA2_TM PF14575.6 PVD27789.1 - 0.24 12.3 0.6 41 5.1 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD27789.1 - 0.36 11.2 3.5 8.5 6.7 0.5 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Spec3 PF15795.5 PVD27789.1 - 0.69 10.5 8.2 6 7.5 1.7 2.8 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein DUF4328 PF14219.6 PVD27789.1 - 0.79 9.3 8.8 0.21 11.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) MgtE PF01769.16 PVD27789.1 - 0.86 10.0 5.7 15 6.0 0.8 2.6 2 0 0 2 2 2 0 Divalent cation transporter DUF202 PF02656.15 PVD27789.1 - 1.7 9.1 5.0 26 5.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Sigma70_ner PF04546.13 PVD27790.1 - 0.0015 18.5 9.9 0.0015 18.5 9.9 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region PPP4R2 PF09184.11 PVD27790.1 - 0.015 14.9 17.5 0.019 14.6 17.5 1.1 1 0 0 1 1 1 0 PPP4R2 RPA43_OB PF17875.1 PVD27790.1 - 1.8 9.2 3.8 2.5 8.8 3.8 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RVT_1 PF00078.27 PVD27793.1 - 3.9e-22 78.9 0.0 3.4e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_3 PF13927.6 PVD27794.1 - 1.2e-25 89.9 18.7 4.3e-06 27.2 0.1 6.7 7 0 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 PVD27794.1 - 1.2e-21 76.9 28.8 6.2e-07 29.7 0.4 6.4 7 0 0 7 7 7 4 Immunoglobulin domain I-set PF07679.16 PVD27794.1 - 1.7e-17 63.2 1.8 3.9e-06 26.8 0.0 6.5 5 1 0 5 5 5 4 Immunoglobulin I-set domain ig PF00047.25 PVD27794.1 - 2.1e-06 27.8 21.8 0.028 14.6 0.2 7.9 9 2 1 10 10 10 4 Immunoglobulin domain V-set PF07686.17 PVD27794.1 - 2.6e-05 24.4 13.6 0.047 13.9 0.0 6.9 7 1 0 7 7 7 3 Immunoglobulin V-set domain zf-C3HC4_3 PF13920.6 PVD27795.1 - 6.5e-07 29.1 13.8 1.2e-06 28.3 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 PVD27795.1 - 1.4e-06 28.8 0.0 0.0026 18.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD27795.1 - 6.2e-05 23.3 0.1 0.0059 17.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 PVD27795.1 - 0.0068 16.7 0.0 0.31 11.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD27795.1 - 0.023 15.3 0.0 0.075 13.6 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Prok-RING_4 PF14447.6 PVD27795.1 - 0.037 13.9 15.4 0.067 13.1 15.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ig PF00047.25 PVD27796.1 - 8.8e-06 25.8 0.5 3.7e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27796.1 - 0.00022 21.7 2.5 0.00039 20.9 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.6 PVD27796.1 - 0.00033 20.6 0.0 0.00033 20.6 0.0 3.2 3 1 0 4 4 4 1 TMEM154 protein family Ig_2 PF13895.6 PVD27796.1 - 0.0051 17.1 0.0 0.018 15.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27796.1 - 0.012 15.7 0.0 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain LCE6A PF15858.5 PVD27796.1 - 0.014 16.2 0.7 0.014 16.2 0.7 3.5 3 1 0 3 3 3 0 Late cornified envelope protein 6A family V-set PF07686.17 PVD27796.1 - 0.048 13.8 0.1 0.22 11.7 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain TMEM52 PF14979.6 PVD27796.1 - 0.064 13.2 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 0 Transmembrane 52 LRRC37AB_C PF14914.6 PVD27796.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain Allexi_40kDa PF05549.11 PVD27797.1 - 0.027 14.0 0.7 0.027 14.0 0.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Mei5_like PF17021.5 PVD27797.1 - 0.059 13.4 2.2 0.16 12.0 2.2 1.7 1 0 0 1 1 1 0 Putative double-strand recombination repair-like Ig_3 PF13927.6 PVD27798.1 - 1.7e-06 28.5 39.8 0.14 12.8 0.7 7.4 6 2 0 6 6 6 5 Immunoglobulin domain TMEM154 PF15102.6 PVD27798.1 - 4.8e-06 26.5 0.1 0.021 14.7 0.0 3.0 3 0 0 3 3 3 2 TMEM154 protein family EphA2_TM PF14575.6 PVD27798.1 - 9.5e-06 26.4 0.0 0.11 13.4 0.0 3.0 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 PVD27798.1 - 4.6e-05 23.3 0.2 0.049 13.6 0.2 2.6 2 0 0 2 2 2 2 DAP10 membrane protein ig PF00047.25 PVD27798.1 - 0.00033 20.8 1.5 0.00033 20.8 1.5 7.6 6 4 2 8 8 8 1 Immunoglobulin domain RNA_pol_A_bac PF01000.26 PVD27798.1 - 0.004 17.5 0.1 7.7 6.9 0.1 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain Adeno_E3_CR2 PF02439.15 PVD27798.1 - 0.0099 15.6 14.1 0.18 11.6 2.8 2.9 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 PRIMA1 PF16101.5 PVD27798.1 - 0.019 15.0 0.5 0.46 10.5 0.0 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF4064 PF13273.6 PVD27798.1 - 0.03 14.6 2.2 1 9.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Syndecan PF01034.20 PVD27798.1 - 0.039 13.9 2.1 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Syndecan domain DUF5385 PF17359.2 PVD27798.1 - 0.072 12.6 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Rax2 PF12768.7 PVD27798.1 - 0.088 12.3 0.4 14 5.1 0.1 2.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity EGF_3 PF12947.7 PVD27798.1 - 0.23 11.7 7.7 2.7 8.3 1.1 3.8 2 0 0 2 2 2 0 EGF domain DUF4834 PF16118.5 PVD27798.1 - 0.3 12.1 2.2 13 6.8 0.0 3.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) DUF347 PF03988.12 PVD27798.1 - 0.51 10.6 4.6 3.5 7.9 0.7 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) RIFIN PF02009.16 PVD27798.1 - 4.6 7.1 9.0 2 8.2 0.1 3.2 4 0 0 4 4 4 0 Rifin Amnionless PF14828.6 PVD27799.1 - 8.2e-10 38.1 7.1 0.052 12.4 0.1 5.2 4 1 1 5 5 5 4 Amnionless TMEM154 PF15102.6 PVD27799.1 - 3.8e-09 36.6 8.1 0.03 14.2 0.0 5.8 6 0 0 6 6 5 3 TMEM154 protein family EphA2_TM PF14575.6 PVD27799.1 - 3.9e-09 37.2 12.7 0.22 12.4 0.1 6.0 6 0 0 6 6 5 3 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 PVD27799.1 - 1.2e-07 32.3 59.6 0.013 16.1 2.2 10.4 9 2 0 9 9 9 5 Immunoglobulin domain DAP10 PF07213.11 PVD27799.1 - 4.3e-06 26.6 7.8 0.0023 17.8 0.5 4.1 4 0 0 4 4 4 2 DAP10 membrane protein DUF2207 PF09972.9 PVD27799.1 - 1.3e-05 24.2 0.3 8.6 5.0 0.0 5.2 4 1 2 6 6 6 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 PVD27799.1 - 2.7e-05 24.4 15.4 0.28 11.5 0.4 5.4 5 0 0 5 5 5 2 Protein of unknown function (DUF4064) CD99L2 PF12301.8 PVD27799.1 - 0.00045 20.6 4.6 1.7 8.9 0.1 4.0 3 0 0 3 3 3 2 CD99 antigen like protein 2 Ig_2 PF13895.6 PVD27799.1 - 0.0012 19.2 54.1 0.011 16.0 0.8 10.0 11 1 0 11 11 10 3 Immunoglobulin domain DUF4690 PF15756.5 PVD27799.1 - 0.0017 18.9 23.7 0.31 11.6 0.1 6.2 6 0 0 6 6 5 2 Small Novel Rich in Cartilage Yip1 PF04893.17 PVD27799.1 - 0.0043 16.8 6.4 6.1 6.5 0.0 4.9 5 0 0 5 5 5 1 Yip1 domain DUF5305 PF17231.2 PVD27799.1 - 0.0066 15.9 16.9 0.44 9.9 0.1 5.2 5 0 0 5 5 5 2 Family of unknown function (DUF5305) DUF4366 PF14283.6 PVD27799.1 - 0.013 15.6 11.7 3.2 7.8 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4366) SIT PF15330.6 PVD27799.1 - 0.021 15.3 0.0 11 6.5 0.0 4.1 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT CbtA PF09490.10 PVD27799.1 - 0.081 12.7 2.3 8.6 6.0 0.0 3.9 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtA) BPD_transp_2 PF02653.16 PVD27799.1 - 0.1 11.8 12.1 1.6 7.8 0.0 4.5 5 0 0 5 5 5 0 Branched-chain amino acid transport system / permease component ABC2_membrane_3 PF12698.7 PVD27799.1 - 0.12 11.5 1.1 14 4.7 0.1 3.2 4 0 0 4 4 4 0 ABC-2 family transporter protein DUF347 PF03988.12 PVD27799.1 - 0.15 12.2 15.6 5.2 7.3 1.0 5.2 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) CwsA PF10814.8 PVD27799.1 - 0.15 12.2 2.1 9.2 6.4 0.3 2.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA TraT PF05818.12 PVD27799.1 - 0.2 11.4 6.1 0.51 10.0 0.1 3.7 3 1 0 3 3 3 0 Enterobacterial TraT complement resistance protein PRIMA1 PF16101.5 PVD27799.1 - 0.25 11.4 0.0 0.25 11.4 0.0 5.1 7 0 0 7 7 6 0 Proline-rich membrane anchor 1 I-set PF07679.16 PVD27799.1 - 0.31 11.1 15.9 8.4 6.5 0.1 7.0 8 0 0 8 8 6 0 Immunoglobulin I-set domain V-set PF07686.17 PVD27799.1 - 1.8 8.7 15.6 2.4 8.4 0.3 4.7 4 0 0 4 4 4 0 Immunoglobulin V-set domain DUF2062 PF09835.9 PVD27799.1 - 3.7 7.4 11.3 25 4.7 0.0 4.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2062) Syndecan PF01034.20 PVD27799.1 - 4.6 7.2 34.6 3 7.8 2.7 5.4 5 0 0 5 5 5 0 Syndecan domain DUF5385 PF17359.2 PVD27799.1 - 4.9 6.7 9.3 13 5.3 0.0 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5385) DUF5007 PF16398.5 PVD27800.1 - 0.056 13.1 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) C1q PF00386.21 PVD27801.1 - 6e-15 55.6 0.0 6.6e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain PA14 PF07691.12 PVD27801.1 - 0.0017 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 PA14 domain C1q PF00386.21 PVD27802.1 - 3.9e-14 53.0 0.1 4.6e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 C1q domain Amnionless PF14828.6 PVD27803.1 - 2.8e-05 23.1 0.0 0.21 10.4 0.0 3.1 3 0 0 3 3 3 1 Amnionless RCR PF12273.8 PVD27803.1 - 4.2e-05 24.2 0.1 0.33 11.6 0.1 4.0 3 0 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red DUF5305 PF17231.2 PVD27803.1 - 4.6e-05 22.9 2.4 3 7.2 0.0 4.0 4 0 0 4 4 4 2 Family of unknown function (DUF5305) EphA2_TM PF14575.6 PVD27803.1 - 8.5e-05 23.4 3.9 5.9 7.9 2.6 4.1 4 1 0 4 4 3 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD27803.1 - 0.00028 20.7 7.1 3.8 7.5 3.0 3.6 3 0 0 3 3 3 1 Syndecan domain DUF2207 PF09972.9 PVD27803.1 - 0.00069 18.5 0.1 6.6 5.4 0.0 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MSP1a PF11670.8 PVD27803.1 - 0.0048 16.2 0.0 6.1 6.1 0.0 3.3 4 0 0 4 4 4 1 Major surface protein 1a (MSP1a) Adeno_E3_CR2 PF02439.15 PVD27803.1 - 0.0076 16.0 30.9 0.084 12.6 3.3 3.5 3 0 0 3 3 3 3 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 PVD27803.1 - 0.009 15.9 8.9 22 5.0 0.1 4.3 4 0 0 4 4 4 0 TMEM154 protein family DUF4064 PF13273.6 PVD27803.1 - 0.0093 16.2 6.1 12 6.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 PVD27803.1 - 0.015 15.7 3.5 4 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Yip1 PF04893.17 PVD27803.1 - 0.025 14.3 0.7 27 4.4 0.0 3.1 3 0 0 3 3 3 0 Yip1 domain Trep_Strep PF09605.10 PVD27803.1 - 0.026 14.5 8.8 1 9.3 0.2 3.0 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CYSTM PF12734.7 PVD27803.1 - 0.028 14.7 0.0 24 5.3 0.0 3.3 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance DUF4381 PF14316.6 PVD27803.1 - 0.033 14.4 0.0 74 3.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Cadherin_C_2 PF16492.5 PVD27803.1 - 0.044 14.5 0.0 56 4.6 0.0 3.9 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal Plasmod_dom_1 PF09715.10 PVD27803.1 - 0.064 13.3 0.1 29 4.8 0.0 3.0 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF1161 PF06649.12 PVD27803.1 - 0.065 13.4 0.5 36 4.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1161) DUF443 PF04276.12 PVD27803.1 - 0.071 12.9 1.3 42 3.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF443) TMEM132D_C PF15706.5 PVD27803.1 - 0.071 12.9 0.0 34 4.3 0.0 3.2 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Glycoprotein_G PF00802.19 PVD27803.1 - 0.13 11.6 6.7 0.32 10.3 5.4 2.2 3 0 0 3 3 3 0 Pneumovirus attachment glycoprotein G DUF5385 PF17359.2 PVD27803.1 - 0.28 10.7 5.9 6.8 6.2 0.1 3.5 4 0 0 4 4 3 0 Family of unknown function (DUF5385) Stevor PF17410.2 PVD27803.1 - 0.28 10.7 7.5 5.3 6.5 0.1 3.4 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame BatA PF07584.11 PVD27803.1 - 0.37 11.2 5.5 41 4.6 0.1 3.3 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF4006 PF13179.6 PVD27803.1 - 1.1 9.2 5.9 64 3.6 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) PGF-CTERM PF18204.1 PVD27803.1 - 1.8 8.6 16.5 3.5 7.7 1.7 3.6 3 0 0 3 3 3 0 PGF-CTERM motif DUF347 PF03988.12 PVD27803.1 - 4.6 7.5 11.4 33 4.8 0.1 3.3 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) MAP17 PF15807.5 PVD27803.1 - 7.6 6.8 5.4 3e+02 1.6 0.2 3.3 4 0 0 4 4 4 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Amnionless PF14828.6 PVD27804.1 - 4.4e-11 42.3 4.1 0.092 11.6 0.0 5.7 5 1 1 6 6 6 3 Amnionless EphA2_TM PF14575.6 PVD27804.1 - 3.9e-10 40.5 8.1 0.58 11.1 0.0 6.1 5 1 1 6 6 5 3 Ephrin type-A receptor 2 transmembrane domain Trs65 PF12735.7 PVD27804.1 - 5.9e-09 35.8 1.6 0.058 12.8 0.0 4.2 4 0 0 4 4 4 2 TRAPP trafficking subunit Trs65 Herpes_gE PF02480.16 PVD27804.1 - 7.7e-09 34.8 0.0 0.0023 16.8 0.0 4.3 5 0 0 5 5 4 2 Alphaherpesvirus glycoprotein E SIT PF15330.6 PVD27804.1 - 2.8e-07 31.0 0.0 0.37 11.3 0.0 4.7 4 0 0 4 4 4 1 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 PVD27804.1 - 8.5e-06 25.7 7.9 0.99 9.3 0.0 5.3 5 0 0 5 5 4 1 TMEM154 protein family Stevor PF17410.2 PVD27804.1 - 1.8e-05 24.4 8.5 1.3 8.6 0.1 4.5 4 0 0 4 4 4 2 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 PVD27804.1 - 2.1e-05 23.5 0.6 4.5 5.9 0.0 5.3 5 0 0 5 5 5 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 PVD27804.1 - 0.00036 20.4 37.5 0.14 12.1 0.0 6.3 6 0 0 6 6 6 3 Syndecan domain Oxidored_q3 PF00499.20 PVD27804.1 - 0.00043 20.0 0.0 10 5.8 0.0 4.9 5 0 0 5 5 5 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ig PF00047.25 PVD27804.1 - 0.00056 20.0 25.0 3.7 7.8 0.1 9.1 6 2 1 7 7 7 1 Immunoglobulin domain RCR PF12273.8 PVD27804.1 - 0.00066 20.3 4.8 5.7 7.6 0.2 5.1 4 0 0 4 4 4 0 Chitin synthesis regulation, resistance to Congo red DcuC PF03606.15 PVD27804.1 - 0.0014 17.1 0.0 0.71 8.3 0.0 3.1 3 0 0 3 3 3 1 C4-dicarboxylate anaerobic carrier C1-set PF07654.15 PVD27804.1 - 0.0015 18.9 28.2 0.32 11.4 1.4 6.6 6 0 0 6 6 5 2 Immunoglobulin C1-set domain Glycophorin_A PF01102.18 PVD27804.1 - 0.002 18.3 16.5 1.4 9.2 0.0 5.9 6 0 0 6 6 5 1 Glycophorin A DUF5385 PF17359.2 PVD27804.1 - 0.01 15.4 9.2 17 4.9 0.1 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5385) DUF4371 PF14291.6 PVD27804.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) TctB PF07331.11 PVD27804.1 - 0.018 15.3 2.6 2.6 8.3 0.0 4.4 5 0 0 5 5 5 0 Tripartite tricarboxylate transporter TctB family BatA PF07584.11 PVD27804.1 - 0.021 15.2 8.6 38 4.7 0.3 4.5 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal DUF5305 PF17231.2 PVD27804.1 - 0.021 14.2 10.0 9.5 5.6 0.0 6.0 6 0 0 6 6 6 0 Family of unknown function (DUF5305) ASFV_J13L PF05568.11 PVD27804.1 - 0.029 14.1 9.8 5.7 6.7 0.3 5.0 5 0 0 5 5 5 0 African swine fever virus J13L protein PepSY_TM PF03929.16 PVD27804.1 - 0.044 13.5 0.1 26 4.3 0.0 4.1 4 0 0 4 4 4 0 PepSY-associated TM region Ni_hydr_CYTB PF01292.20 PVD27804.1 - 0.051 13.2 0.5 93 2.5 0.0 4.5 5 0 0 5 5 5 0 Prokaryotic cytochrome b561 DUF4064 PF13273.6 PVD27804.1 - 0.052 13.8 22.4 6.5 7.1 0.3 5.5 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) DUF2367 PF10164.9 PVD27804.1 - 0.07 13.6 2.1 15 6.2 0.0 4.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) C2-set_2 PF08205.12 PVD27804.1 - 0.11 12.5 25.5 3.1 7.9 0.1 9.1 8 1 0 8 8 8 0 CD80-like C2-set immunoglobulin domain DUF443 PF04276.12 PVD27804.1 - 0.12 12.1 13.0 0.97 9.2 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF443) DUF4381 PF14316.6 PVD27804.1 - 0.13 12.5 6.1 76 3.5 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4381) DUF2158 PF09926.9 PVD27804.1 - 0.17 11.7 1.3 10 6.0 0.1 2.9 3 0 0 3 3 2 0 Uncharacterized small protein (DUF2158) DUF3827 PF12877.7 PVD27804.1 - 0.18 10.1 8.8 7.6 4.8 0.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3827) DUF780 PF05611.11 PVD27804.1 - 0.28 12.0 5.6 28 5.6 0.4 3.9 3 0 0 3 3 3 0 Caenorhabditis elegans protein of unknown function (DUF780) OAD_gamma PF04277.13 PVD27804.1 - 0.37 11.4 7.6 35 5.1 0.0 5.4 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain Ig_2 PF13895.6 PVD27804.1 - 0.44 10.9 52.1 0.88 10.0 1.3 9.3 11 0 0 11 11 7 0 Immunoglobulin domain PsaL PF02605.15 PVD27804.1 - 0.47 10.1 10.5 81 2.8 0.0 5.7 5 1 1 6 6 6 0 Photosystem I reaction centre subunit XI TRP PF06011.12 PVD27804.1 - 0.56 8.9 9.6 23 3.6 0.1 4.7 5 0 0 5 5 5 0 Transient receptor potential (TRP) ion channel S1FA PF04689.13 PVD27804.1 - 1.1 9.5 17.9 1.3 9.2 0.3 5.3 5 0 0 5 5 5 0 DNA binding protein S1FA ODV-E18 PF10717.9 PVD27804.1 - 1.1 9.2 10.7 37 4.3 0.2 4.8 4 0 0 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 Rax2 PF12768.7 PVD27804.1 - 3 7.2 8.2 14 5.0 0.0 4.3 5 0 0 5 5 4 0 Cortical protein marker for cell polarity Phage_holin_3_6 PF07332.11 PVD27804.1 - 4 7.5 18.8 30 4.7 0.9 5.1 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III KleE PF17394.2 PVD27804.1 - 4.6 7.5 8.2 1.4e+02 2.7 0.1 4.9 5 0 0 5 5 5 0 Uncharacterized KleE stable inheritance protein RIFIN PF02009.16 PVD27804.1 - 9 6.1 18.0 3.6 7.4 0.1 4.8 5 0 0 5 5 4 0 Rifin Ig_3 PF13927.6 PVD27805.1 - 1.1e-30 106.1 46.2 9.1e-06 26.2 0.2 12.2 10 1 1 11 11 11 8 Immunoglobulin domain I-set PF07679.16 PVD27805.1 - 1.1e-29 102.3 14.1 9.9e-07 28.7 0.1 10.2 10 0 0 10 10 10 5 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27805.1 - 4.9e-29 100.5 37.7 6.4e-07 29.6 1.0 8.9 8 0 0 8 8 8 6 Immunoglobulin domain ig PF00047.25 PVD27805.1 - 6.3e-20 71.2 34.1 0.031 14.4 0.2 12.0 11 1 0 11 11 11 7 Immunoglobulin domain C2-set_2 PF08205.12 PVD27805.1 - 7.4e-09 35.6 26.5 0.014 15.5 0.2 9.1 9 1 0 9 9 9 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27805.1 - 1.4e-05 25.2 30.9 2.6 8.3 0.8 11.4 11 3 2 13 13 13 3 Immunoglobulin V-set domain DUF4448 PF14610.6 PVD27805.1 - 0.0013 18.6 4.1 0.13 12.0 0.2 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4448) LAX PF15681.5 PVD27805.1 - 0.0046 15.8 3.4 0.047 12.5 1.4 2.4 2 0 0 2 2 2 1 Lymphocyte activation family X DUF5305 PF17231.2 PVD27805.1 - 0.006 16.0 0.5 0.46 9.8 0.0 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5305) PCNA_N PF00705.18 PVD27805.1 - 0.023 14.4 0.0 8.8 6.1 0.0 2.8 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain EphA2_TM PF14575.6 PVD27805.1 - 0.096 13.6 1.5 19 6.2 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 PVD27805.1 - 0.13 12.5 1.3 2.1 8.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Orf78 PF06024.12 PVD27805.1 - 0.15 12.3 0.9 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Ig_C17orf99 PF17736.1 PVD27805.1 - 0.21 11.7 9.5 7.7 6.6 0.0 4.7 5 0 0 5 5 4 0 C17orf99 Ig domain MAP17 PF15807.5 PVD27805.1 - 0.28 11.4 1.2 5.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HemY_N PF07219.13 PVD27805.1 - 0.49 10.6 4.1 14 6.0 0.6 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Stevor PF17410.2 PVD27805.1 - 0.66 9.5 4.6 0.84 9.1 0.3 2.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF3357 PF11837.8 PVD27805.1 - 0.9 10.0 3.1 4.4 7.8 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) I-set PF07679.16 PVD27806.1 - 5.6e-36 122.5 6.0 2.9e-08 33.6 0.1 10.5 9 1 0 9 9 9 6 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27806.1 - 2.3e-33 114.6 46.5 1e-07 32.4 2.6 11.2 10 2 0 10 10 10 7 Immunoglobulin domain ig PF00047.25 PVD27806.1 - 1.8e-22 79.3 33.3 0.0029 17.7 0.0 11.8 9 3 1 10 10 10 7 Immunoglobulin domain Ig_2 PF13895.6 PVD27806.1 - 6.6e-22 77.6 42.5 0.00012 22.4 0.1 9.5 9 0 0 9 9 8 5 Immunoglobulin domain V-set PF07686.17 PVD27806.1 - 6.4e-18 64.9 21.3 0.0025 18.0 0.0 10.9 10 2 0 11 11 11 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD27806.1 - 3.5e-07 30.2 26.9 0.013 15.5 0.2 7.9 8 1 0 8 8 7 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD27806.1 - 2e-06 27.8 4.4 4.9 7.3 0.0 7.3 8 0 0 8 8 7 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD27806.1 - 1.6e-05 24.4 1.4 0.78 9.4 0.0 5.4 5 0 0 5 5 5 1 Immunoglobulin domain DUF4448 PF14610.6 PVD27806.1 - 0.00011 22.1 3.5 0.052 13.3 0.1 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 PVD27806.1 - 0.0034 17.3 1.2 0.026 14.5 0.1 2.5 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 PVD27806.1 - 0.015 15.6 1.3 0.72 10.2 0.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) MAP17 PF15807.5 PVD27806.1 - 0.053 13.8 0.7 0.46 10.7 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 C2-set PF05790.15 PVD27806.1 - 0.093 12.9 11.3 8.9 6.6 0.0 6.2 8 0 0 8 8 7 0 Immunoglobulin C2-set domain DUF4191 PF13829.6 PVD27806.1 - 0.32 10.3 4.7 1.4 8.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Vpu PF00558.19 PVD27806.1 - 1 9.2 6.0 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 Vpu protein DUF4059 PF13268.6 PVD27806.1 - 1.1 9.7 6.8 0.91 10.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Myc_target_1 PF15179.6 PVD27806.1 - 2.4 8.0 6.6 0.24 11.3 0.1 2.6 3 0 0 3 3 2 0 Myc target protein 1 Pox_EPC_I2-L1 PF12575.8 PVD27806.1 - 6.8 7.0 6.7 14 6.0 0.5 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 I-set PF07679.16 PVD27808.1 - 7.3e-14 51.6 1.8 1.8e-07 31.2 0.1 4.6 4 2 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27808.1 - 1.5e-10 41.5 17.1 1.4e-06 28.8 0.7 5.0 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 PVD27808.1 - 9.4e-08 32.2 7.2 0.0025 17.9 0.2 4.8 4 2 0 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 PVD27808.1 - 1.7e-06 28.1 16.3 0.00045 20.3 0.3 5.0 5 1 1 6 6 6 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27808.1 - 1.1e-05 25.7 10.2 9.5e-05 22.7 0.3 3.6 3 1 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27808.1 - 0.0041 17.1 0.6 4 7.6 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain HemY_N PF07219.13 PVD27808.1 - 0.12 12.6 0.4 0.21 11.8 0.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus I-set PF07679.16 PVD27809.1 - 1.3e-48 163.0 22.1 1.5e-08 34.6 0.1 16.8 18 2 0 18 18 16 8 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27809.1 - 1.2e-45 154.0 81.8 3.1e-07 30.9 2.8 18.2 18 0 0 18 18 18 9 Immunoglobulin domain Ig_2 PF13895.6 PVD27809.1 - 6.9e-34 116.0 68.4 6.2e-05 23.3 0.2 14.5 13 0 0 13 13 13 9 Immunoglobulin domain ig PF00047.25 PVD27809.1 - 2.9e-25 88.2 60.8 0.00098 19.3 0.0 17.0 16 1 0 16 16 16 8 Immunoglobulin domain C2-set_2 PF08205.12 PVD27809.1 - 2.1e-13 50.2 47.6 0.0018 18.3 0.1 13.6 15 0 0 15 15 12 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27809.1 - 1.6e-12 47.6 55.9 0.33 11.1 0.1 18.8 22 0 0 22 22 20 4 Immunoglobulin V-set domain DUF4448 PF14610.6 PVD27809.1 - 0.00014 21.7 6.2 0.024 14.4 0.3 5.0 4 2 0 4 4 4 1 Protein of unknown function (DUF4448) B_solenoid_ydck PF18836.1 PVD27809.1 - 0.00072 19.3 3.6 7 6.7 0.0 5.2 5 0 0 5 5 5 1 Beta solenoid repeat from YDCK Izumo-Ig PF16706.5 PVD27809.1 - 0.0012 18.9 10.1 56 3.9 0.0 9.3 11 0 0 11 11 10 0 Izumo-like Immunoglobulin domain DUF2207 PF09972.9 PVD27809.1 - 0.0094 14.8 0.1 0.18 10.6 0.0 3.0 4 0 0 4 4 4 1 Predicted membrane protein (DUF2207) DUF1652 PF07865.11 PVD27809.1 - 0.051 13.4 0.2 22 4.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) MAP17 PF15807.5 PVD27809.1 - 0.08 13.2 3.6 30 4.9 0.1 3.4 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Stevor PF17410.2 PVD27809.1 - 0.1 12.1 7.0 4.3 6.8 0.6 3.2 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame Atg29_N PF18388.1 PVD27809.1 - 0.14 12.0 0.4 0.77 9.6 0.1 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain EphA2_TM PF14575.6 PVD27809.1 - 0.21 12.5 8.5 48 4.9 0.3 4.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD27809.1 - 0.28 11.5 9.6 37 4.7 1.0 4.2 4 0 0 4 4 4 0 Orf78 (ac78) TMEM154 PF15102.6 PVD27809.1 - 0.32 10.9 3.7 17 5.3 0.0 3.6 3 0 0 3 3 3 0 TMEM154 protein family MgtE PF01769.16 PVD27809.1 - 0.55 10.6 10.7 18 5.7 0.6 4.0 4 0 0 4 4 4 0 Divalent cation transporter HemY_N PF07219.13 PVD27809.1 - 0.61 10.3 17.1 5.4 7.3 0.0 4.1 4 0 0 4 4 4 0 HemY protein N-terminus DUF4234 PF14018.6 PVD27809.1 - 2 8.6 6.5 43 4.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) DUF4191 PF13829.6 PVD27809.1 - 4.4 6.6 8.9 10 5.4 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF4381 PF14316.6 PVD27809.1 - 7.2 6.8 12.9 11 6.2 0.9 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) LRR19-TM PF15176.6 PVD27809.1 - 9 6.4 6.1 28 4.8 0.3 2.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain SRCR PF00530.18 PVD27810.1 - 7.4e-26 90.6 5.6 5.3e-11 42.9 0.1 3.5 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Ribosomal_L13 PF00572.18 PVD27810.1 - 0.1 12.9 0.0 15 5.9 0.0 3.0 2 1 1 3 3 3 0 Ribosomal protein L13 EF-hand_7 PF13499.6 PVD27811.1 - 9.7e-18 64.4 10.6 0.041 14.3 0.0 6.6 4 4 2 6 6 6 6 EF-hand domain pair EF-hand_1 PF00036.32 PVD27811.1 - 4.8e-16 57.0 18.8 0.0087 15.5 0.1 7.6 6 2 2 8 8 8 5 EF hand EF-hand_5 PF13202.6 PVD27811.1 - 4.1e-13 48.2 19.8 0.00079 18.8 0.1 7.5 7 1 1 8 8 8 6 EF hand EF-hand_6 PF13405.6 PVD27811.1 - 3.8e-12 45.1 13.8 0.23 11.5 0.0 7.5 6 2 2 8 8 8 4 EF-hand domain EF-hand_8 PF13833.6 PVD27811.1 - 8.2e-12 44.8 10.1 0.56 10.1 0.0 6.6 4 2 2 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27811.1 - 0.00036 20.8 0.4 3.5 8.0 0.0 4.4 2 2 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD27811.1 - 0.00038 20.6 0.6 8 6.7 0.0 5.1 6 0 0 6 6 6 1 Dockerin type I domain Excalibur PF05901.11 PVD27811.1 - 0.041 14.5 6.6 33 5.2 0.0 4.6 4 1 0 4 4 4 0 Excalibur calcium-binding domain DUF4478 PF14793.6 PVD27811.1 - 0.15 12.0 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases EF-hand_4 PF12763.7 PVD27811.1 - 0.15 12.0 0.3 8.9 6.3 0.0 2.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TMEM173 PF15009.6 PVD27812.1 - 0.23 10.6 0.1 0.3 10.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 EF-hand_8 PF13833.6 PVD27813.1 - 1.3e-07 31.3 8.9 0.00049 19.9 0.5 3.8 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD27813.1 - 3.1e-07 29.4 11.2 0.0016 17.8 0.2 5.0 3 2 2 5 5 5 2 EF hand EF-hand_7 PF13499.6 PVD27813.1 - 3.9e-07 30.4 11.4 0.0013 19.1 1.1 4.8 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD27813.1 - 5.1e-07 28.9 15.4 0.0017 17.7 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PVD27813.1 - 2.8e-05 23.7 11.6 1.3 9.2 0.1 5.8 5 1 1 6 6 6 3 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD27813.1 - 0.071 13.4 0.6 21 5.5 0.0 3.6 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Keratin_2_head PF16208.5 PVD27813.1 - 0.089 12.9 19.0 0.18 11.9 19.0 1.4 1 0 0 1 1 1 0 Keratin type II head EF-hand_4 PF12763.7 PVD27813.1 - 0.38 10.7 1.6 27 4.8 0.2 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TetR_C_21 PF17926.1 PVD27813.1 - 0.89 9.7 3.8 24 5.1 0.1 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain I-set PF07679.16 PVD27814.1 - 3.4e-16 59.1 0.1 1.9e-09 37.5 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27814.1 - 4e-15 56.2 0.9 8.1e-09 36.0 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27814.1 - 1.4e-09 38.2 0.2 7.8e-08 32.6 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD27814.1 - 7e-08 32.5 0.6 0.0023 18.1 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD27814.1 - 2e-07 31.1 0.2 0.0065 16.6 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 PVD27814.1 - 0.0075 16.0 0.1 0.94 9.3 0.0 2.6 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 PGBA_N PF15436.6 PVD27814.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal EF-hand_1 PF00036.32 PVD27815.1 - 4.6e-10 38.3 5.8 0.00044 19.6 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 PVD27815.1 - 5.6e-10 39.5 4.6 1.8e-06 28.3 1.3 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD27815.1 - 1e-09 37.5 3.5 0.0039 16.6 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 PVD27815.1 - 4.3e-06 26.2 6.9 0.019 14.9 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 PVD27815.1 - 8.8e-05 22.3 3.4 0.18 11.7 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair Dockerin_1 PF00404.18 PVD27815.1 - 0.59 10.4 5.4 14 6.0 0.0 3.3 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_1 PF00036.32 PVD27816.1 - 2.3e-11 42.4 6.8 0.0019 17.6 0.1 3.8 3 2 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD27816.1 - 3.3e-11 43.5 1.6 2.3e-05 24.8 0.7 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD27816.1 - 2.9e-09 36.0 5.0 0.0087 15.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD27816.1 - 5.8e-09 35.2 4.6 0.036 14.0 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PVD27816.1 - 2.9e-05 23.8 1.5 0.18 11.7 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair ATPgrasp_N PF18130.1 PVD27816.1 - 0.024 15.2 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp N-terminal domain FG-GAP PF01839.23 PVD27816.1 - 0.062 13.5 3.0 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 FG-GAP repeat EF-hand_1 PF00036.32 PVD27817.1 - 5.3e-10 38.1 5.0 0.00015 21.0 0.1 3.4 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD27817.1 - 3.7e-09 36.9 1.3 4.3e-07 30.3 1.3 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD27817.1 - 8e-07 28.3 3.6 0.006 16.0 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD27817.1 - 1.7e-06 27.8 1.3 0.003 17.4 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD27817.1 - 5.1e-06 26.0 4.5 0.4 10.7 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain SRCR PF00530.18 PVD27818.1 - 2.9e-28 98.3 9.4 3.2e-16 59.6 0.5 3.1 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ig_2 PF13895.6 PVD27818.1 - 2.3e-07 31.1 2.2 7.4e-07 29.4 2.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD27818.1 - 1.9e-05 25.2 5.5 2.2e-05 25.0 2.5 2.6 3 1 0 3 3 3 1 Immunoglobulin domain SRCR_2 PF15494.6 PVD27818.1 - 5.1e-05 23.7 2.5 0.0015 19.0 0.4 2.4 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain ig PF00047.25 PVD27818.1 - 0.0013 18.8 1.0 0.019 15.1 1.0 2.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD27818.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF108 PF01958.18 PVD27818.1 - 0.094 13.1 0.4 4.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF108 MACPF PF01823.19 PVD27819.1 - 1.2e-21 77.8 0.1 2.5e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Fibrinogen_C PF00147.18 PVD27819.1 - 0.0094 15.8 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MACPF PF01823.19 PVD27820.1 - 1.2e-22 81.1 2.5 1.2e-22 81.0 0.1 2.2 2 1 0 2 2 2 1 MAC/Perforin domain PAN_4 PF14295.6 PVD27820.1 - 0.00095 19.0 9.3 0.016 15.1 1.3 2.7 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 PVD27820.1 - 0.3 10.9 16.4 0.33 10.8 2.2 3.1 3 0 0 3 3 3 0 PAN-like domain Fibrinogen_C PF00147.18 PVD27821.1 - 2.4e-13 50.4 2.9 3.1e-13 50.0 2.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SRCR PF00530.18 PVD27822.1 - 2e-10 41.1 0.9 5.6e-10 39.6 0.3 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27822.1 - 2.4e-07 31.3 0.1 7.1e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27822.1 - 2.8e-06 27.3 0.1 1.5e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27822.1 - 0.00046 20.5 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain MACPF PF01823.19 PVD27823.1 - 2.6e-22 79.9 0.1 7.6e-22 78.4 0.1 1.8 1 1 0 1 1 1 1 MAC/Perforin domain PAN_4 PF14295.6 PVD27823.1 - 0.0003 20.6 8.4 0.065 13.1 2.5 2.8 2 0 0 2 2 2 2 PAN domain EB PF01683.18 PVD27823.1 - 0.013 15.8 8.2 0.013 15.8 8.2 2.5 2 2 0 2 2 2 0 EB module PAN_3 PF08277.12 PVD27823.1 - 0.54 10.1 15.8 2.1 8.2 1.8 3.1 3 0 0 3 3 3 0 PAN-like domain SRCR PF00530.18 PVD27824.1 - 2.6e-14 53.5 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PVD27825.1 - 1e-72 240.9 22.0 7.3e-17 61.7 0.8 7.8 8 0 0 8 8 8 7 Scavenger receptor cysteine-rich domain I-set PF07679.16 PVD27825.1 - 3.8e-12 46.1 0.1 8e-09 35.5 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain SRCR_2 PF15494.6 PVD27825.1 - 8.4e-12 45.5 5.3 6.6e-05 23.4 0.1 4.3 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27825.1 - 4.1e-11 43.3 1.4 4.9e-08 33.4 0.1 3.6 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD27825.1 - 1.1e-07 32.0 0.6 0.004 17.3 0.2 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 PVD27825.1 - 1.4e-07 31.6 0.3 4.2e-06 26.8 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27825.1 - 3.2e-07 30.6 1.5 6.4e-06 26.4 0.1 3.3 3 0 0 3 3 3 1 Immunoglobulin domain DUF3837 PF12939.7 PVD27825.1 - 0.054 13.9 0.0 7.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF5397 PF17375.2 PVD27825.1 - 0.054 13.2 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5397) Hepsin-SRCR PF09272.10 PVD27825.1 - 0.33 11.5 18.0 0.25 11.9 0.2 4.2 5 0 0 5 5 5 0 Hepsin, SRCR domain zinc_ribbon_13 PF09855.9 PVD27825.1 - 6.2 7.1 8.2 24 5.2 0.2 4.2 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) SRCR PF00530.18 PVD27826.1 - 7.8e-50 167.5 8.3 7.2e-17 61.7 0.0 5.2 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain I-set PF07679.16 PVD27826.1 - 2.5e-38 130.0 0.5 1.2e-10 41.3 0.0 6.2 6 0 0 6 6 6 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27826.1 - 1.8e-31 108.6 12.2 1.4e-08 35.2 0.0 7.2 7 0 0 7 7 7 3 Immunoglobulin domain Ig_2 PF13895.6 PVD27826.1 - 1.7e-27 95.5 11.1 1.1e-08 35.3 0.1 6.0 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 PVD27826.1 - 1e-15 57.6 14.2 4.2e-06 26.8 0.0 5.7 5 2 1 6 6 6 3 Immunoglobulin domain V-set PF07686.17 PVD27826.1 - 4.1e-11 43.0 11.5 0.016 15.4 0.2 6.8 5 3 0 5 5 5 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD27826.1 - 7.4e-09 35.6 0.2 0.37 10.9 0.0 4.2 4 0 0 4 4 4 3 Izumo-like Immunoglobulin domain SRCR_2 PF15494.6 PVD27826.1 - 1.8e-05 25.2 5.4 0.27 11.8 0.2 4.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ig_C17orf99 PF17736.1 PVD27826.1 - 0.0023 17.9 3.7 1.8 8.6 0.0 5.0 5 1 0 5 5 5 1 C17orf99 Ig domain Proteasom_PSMB PF10508.9 PVD27826.1 - 0.1 11.1 0.7 3.5 6.0 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Tobravirus_2B PF05271.11 PVD27826.1 - 0.11 12.4 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Tobravirus 2B protein YmzC PF14157.6 PVD27826.1 - 0.17 11.9 0.1 12 6.1 0.0 2.9 2 0 0 2 2 2 0 YmzC-like protein V4R PF02830.18 PVD27826.1 - 0.24 11.4 0.9 45 4.1 0.0 3.2 3 0 0 3 3 3 0 V4R domain Staphylcoagulse PF04022.12 PVD27826.1 - 5 6.8 4.9 40 3.8 0.6 2.7 2 0 0 2 2 2 0 Staphylocoagulase repeat Syndecan PF01034.20 PVD27826.1 - 6.6 6.7 5.5 8.1 6.5 0.6 2.9 3 0 0 3 3 3 0 Syndecan domain EF-hand_1 PF00036.32 PVD27827.1 - 2.3e-23 79.9 25.2 0.00028 20.2 0.2 7.3 5 2 2 7 7 7 6 EF hand EF-hand_5 PF13202.6 PVD27827.1 - 3.6e-22 76.8 36.1 6.8e-05 22.2 0.4 7.3 5 2 2 7 7 7 7 EF hand EF-hand_6 PF13405.6 PVD27827.1 - 9.1e-19 65.7 21.6 0.008 16.0 0.0 7.3 5 2 2 7 7 7 6 EF-hand domain EF-hand_7 PF13499.6 PVD27827.1 - 6.9e-17 61.7 22.4 1.1e-07 32.1 2.2 5.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PVD27827.1 - 6.2e-14 51.6 21.7 0.018 14.9 0.8 6.6 4 2 3 7 7 7 5 EF-hand domain pair MHC_I PF00129.18 PVD27827.1 - 0.0072 15.9 0.7 2 8.0 0.2 2.3 2 0 0 2 2 2 2 Class I Histocompatibility antigen, domains alpha 1 and 2 TcdB_toxin_midN PF12256.8 PVD27827.1 - 0.55 9.6 5.3 14 5.0 0.1 3.7 3 2 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region SHOCT PF09851.9 PVD27827.1 - 0.95 9.3 4.8 0.32 10.8 0.4 2.6 3 0 0 3 3 3 0 Short C-terminal domain DUF2722 PF10846.8 PVD27827.1 - 8.9 5.1 6.8 12 4.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EF-hand_5 PF13202.6 PVD27828.1 - 1.8e-14 52.5 10.1 0.00026 20.4 0.0 4.2 3 1 1 4 4 4 4 EF hand EF-hand_1 PF00036.32 PVD27828.1 - 1.6e-13 49.2 7.8 0.0011 18.3 0.0 4.2 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD27828.1 - 4.3e-10 38.7 6.0 0.0065 16.3 0.4 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD27828.1 - 1e-09 38.7 2.2 6.7e-07 29.7 2.1 3.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD27828.1 - 5e-05 23.1 10.2 0.2 11.5 0.4 4.0 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27828.1 - 0.13 12.6 0.1 9.7 6.5 0.0 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD27828.1 - 2.3 8.5 11.5 15 5.9 0.1 4.0 2 2 2 4 4 4 0 Dockerin type I domain EF-hand_6 PF13405.6 PVD27829.1 - 5.1e-08 32.2 8.8 0.0032 17.3 0.7 3.2 2 1 1 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PVD27829.1 - 7.5e-08 31.5 11.1 0.00081 18.8 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 PVD27829.1 - 5.1e-07 28.8 11.3 0.0015 18.0 0.5 3.3 2 1 1 3 3 3 3 EF hand EF-hand_7 PF13499.6 PVD27829.1 - 5.7e-07 29.9 6.0 3.5e-06 27.4 6.0 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD27829.1 - 0.0084 15.9 9.1 0.31 10.9 0.3 3.1 2 1 1 3 3 3 2 EF-hand domain pair Excalibur PF05901.11 PVD27829.1 - 0.0085 16.7 3.0 7.1 7.3 0.1 3.4 3 0 0 3 3 3 1 Excalibur calcium-binding domain Ig_3 PF13927.6 PVD27830.1 - 4.5e-08 33.6 0.0 0.014 16.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD27830.1 - 7.4e-06 26.1 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27830.1 - 1.2e-05 25.6 0.4 0.082 13.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain SRCR PF00530.18 PVD27830.1 - 0.014 15.8 2.4 2.4 8.7 0.4 2.5 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain DiSB-ORF2_chro PF16506.5 PVD27830.1 - 0.23 11.5 2.7 20 5.3 0.2 2.9 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses SLATT_5 PF18160.1 PVD27830.1 - 0.41 10.0 3.2 16 4.7 0.1 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 MACPF PF01823.19 PVD27831.1 - 4.8e-18 66.0 0.0 8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain EB PF01683.18 PVD27831.1 - 0.00019 21.7 1.2 0.00019 21.7 1.2 3.1 3 0 0 3 3 3 1 EB module PAN_3 PF08277.12 PVD27831.1 - 0.00067 19.4 8.7 0.021 14.6 1.1 3.2 3 0 0 3 3 3 2 PAN-like domain PAN_4 PF14295.6 PVD27831.1 - 0.00098 19.0 9.6 0.078 12.9 0.3 3.6 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 PVD27831.1 - 0.004 17.2 0.2 0.004 17.2 0.2 3.1 4 0 0 4 4 4 1 PAN-like domain Hyd_WA PF06462.12 PVD27831.1 - 0.15 12.1 4.9 0.87 9.6 0.0 3.4 3 0 0 3 3 3 0 Propeller EF-hand_5 PF13202.6 PVD27832.1 - 2.1e-11 42.7 10.0 0.00033 20.0 0.1 3.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PVD27832.1 - 6.5e-11 41.3 6.8 0.026 14.4 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD27832.1 - 4.7e-10 39.8 2.7 9.1e-07 29.3 1.3 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD27832.1 - 2.9e-09 35.8 9.2 0.00071 19.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD27832.1 - 5.8e-09 35.7 4.3 0.00075 19.3 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27832.1 - 0.00049 20.4 1.4 2.2 8.6 0.0 3.2 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Excalibur PF05901.11 PVD27832.1 - 0.41 11.3 2.3 90 3.8 0.0 3.7 4 0 0 4 4 4 0 Excalibur calcium-binding domain SHOCT PF09851.9 PVD27832.1 - 0.58 10.0 0.1 0.58 10.0 0.1 1.9 2 0 0 2 2 2 0 Short C-terminal domain Dockerin_1 PF00404.18 PVD27832.1 - 1.1 9.5 7.5 17 5.7 0.2 3.5 3 1 0 4 4 4 0 Dockerin type I domain Hyd_WA PF06462.12 PVD27833.1 - 0.00026 20.9 0.1 0.00026 20.9 0.1 2.8 3 0 0 3 3 3 1 Propeller MACPF PF01823.19 PVD27834.1 - 2.5e-19 70.2 0.0 4.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain EB PF01683.18 PVD27834.1 - 9.1e-05 22.7 1.3 9.1e-05 22.7 1.3 3.0 3 0 0 3 3 3 1 EB module PAN_3 PF08277.12 PVD27834.1 - 0.00011 21.9 7.6 0.0082 15.9 0.9 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.6 PVD27834.1 - 0.00025 20.9 7.3 0.036 14.0 0.3 2.9 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD27834.1 - 0.0017 18.4 0.2 0.0017 18.4 0.2 3.0 3 0 0 3 3 3 2 PAN-like domain Sulfatase PF00884.23 PVD27835.1 - 4.7e-76 256.1 0.0 9.1e-76 255.2 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 PVD27835.1 - 1.1e-28 100.4 0.5 1.8e-28 99.7 0.5 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 PVD27835.1 - 3.3e-07 30.2 0.8 3.6e-06 26.8 0.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 PVD27835.1 - 0.0011 19.3 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) EF-hand_6 PF13405.6 PVD27836.1 - 1e-22 78.0 40.5 0.0043 16.9 0.0 9.3 8 2 2 10 10 10 8 EF-hand domain EF-hand_7 PF13499.6 PVD27836.1 - 1.2e-20 73.7 20.4 1.7e-07 31.6 0.1 5.9 2 2 3 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD27836.1 - 2.2e-15 55.0 41.1 0.0015 18.0 0.0 9.4 9 1 1 10 10 10 5 EF hand EF-hand_5 PF13202.6 PVD27836.1 - 5.7e-12 44.5 39.0 0.0026 17.2 0.0 8.4 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 PVD27836.1 - 6.2e-06 26.0 22.5 0.02 14.7 0.1 6.3 5 2 2 7 7 7 2 EF-hand domain pair MetallophosN PF16371.5 PVD27836.1 - 0.0058 16.9 1.7 8.7 6.7 0.0 4.2 4 1 1 5 5 5 1 N terminal of Calcineurin-like phosphoesterase SPARC_Ca_bdg PF10591.9 PVD27836.1 - 0.02 15.2 10.9 8.8 6.7 0.3 5.8 3 3 3 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_30_8 PF06019.11 PVD27836.1 - 0.091 12.7 0.1 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Phage GP30.8 protein PepSY_like PF11396.8 PVD27836.1 - 0.13 12.8 0.1 5.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like EF-hand_7 PF13499.6 PVD27837.1 - 6e-22 77.9 45.3 0.00014 22.3 1.0 13.3 6 6 6 12 12 12 7 EF-hand domain pair EF-hand_1 PF00036.32 PVD27837.1 - 1.9e-18 64.5 62.8 0.022 14.3 0.2 16.8 13 5 5 18 18 18 11 EF hand EF-hand_6 PF13405.6 PVD27837.1 - 1.8e-16 58.6 78.1 0.034 14.1 0.1 18.3 12 9 8 20 20 20 9 EF-hand domain EF-hand_5 PF13202.6 PVD27837.1 - 1.3e-10 40.2 62.5 0.03 13.8 0.2 15.2 16 1 1 17 17 17 6 EF hand EF-hand_8 PF13833.6 PVD27837.1 - 6.4e-05 22.7 39.0 0.058 13.2 0.1 11.6 11 4 2 14 14 14 4 EF-hand domain pair FcoT PF10862.8 PVD27837.1 - 0.021 14.4 0.0 6 6.4 0.0 2.8 2 0 0 2 2 2 0 FcoT-like thioesterase domain SPARC_Ca_bdg PF10591.9 PVD27837.1 - 0.46 10.8 20.6 53 4.2 0.0 9.8 9 5 3 12 12 12 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 PVD27838.1 - 2.2e-09 37.6 11.2 0.0028 18.0 4.2 5.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD27838.1 - 4.7e-08 32.0 24.0 0.047 13.3 0.4 6.5 5 1 1 6 6 6 3 EF hand EF-hand_5 PF13202.6 PVD27838.1 - 1.5e-06 27.4 33.8 0.048 13.2 0.2 7.3 8 0 0 8 8 8 4 EF hand EF-hand_6 PF13405.6 PVD27838.1 - 3.8e-06 26.4 28.6 0.047 13.6 0.4 6.9 6 1 2 8 8 8 3 EF-hand domain FcoT PF10862.8 PVD27838.1 - 0.00027 20.6 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 2 FcoT-like thioesterase domain EF-hand_8 PF13833.6 PVD27838.1 - 0.0003 20.6 11.3 1.7 8.6 0.1 4.8 5 1 0 5 5 5 3 EF-hand domain pair HALZ PF02183.18 PVD27838.1 - 0.0004 20.5 0.1 0.83 9.9 0.0 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper Glycos_transf_2 PF00535.26 PVD27838.1 - 0.044 13.6 0.1 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 RGP PF03214.13 PVD27838.1 - 0.14 11.3 0.0 14 4.7 0.0 2.1 2 0 0 2 2 2 0 Reversibly glycosylated polypeptide Gasdermin PF04598.12 PVD27838.1 - 0.16 11.3 0.0 18 4.7 0.0 2.1 2 0 0 2 2 2 0 Gasdermin pore forming domain EF-hand_7 PF13499.6 PVD27839.1 - 1.2e-11 44.9 19.5 0.0073 16.7 0.3 6.5 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_1 PF00036.32 PVD27839.1 - 8.6e-09 34.3 32.9 0.082 12.5 0.2 10.2 8 1 2 10 10 10 5 EF hand EF-hand_5 PF13202.6 PVD27839.1 - 7.4e-08 31.6 41.3 0.034 13.6 1.1 10.6 12 0 0 12 12 12 4 EF hand EF-hand_6 PF13405.6 PVD27839.1 - 4.5e-06 26.2 46.1 0.4 10.7 0.3 11.3 8 3 4 12 12 12 4 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD27839.1 - 0.0027 18.0 6.6 3.8 7.9 0.2 5.5 6 1 0 6 6 6 2 Secreted protein acidic and rich in cysteine Ca binding region FcoT PF10862.8 PVD27839.1 - 0.064 12.9 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 FcoT-like thioesterase domain EF-hand_8 PF13833.6 PVD27839.1 - 0.084 12.7 24.7 1.7 8.5 0.0 7.5 6 2 2 8 8 8 0 EF-hand domain pair EF-hand_1 PF00036.32 PVD27840.1 - 1.3e-17 61.9 23.9 0.0024 17.3 0.0 8.4 6 2 2 8 8 8 6 EF hand EF-hand_7 PF13499.6 PVD27840.1 - 4.8e-15 55.8 17.9 0.0084 16.5 0.0 7.3 3 3 3 7 7 7 6 EF-hand domain pair EF-hand_5 PF13202.6 PVD27840.1 - 1.5e-13 49.5 33.9 0.0029 17.0 0.0 8.9 9 1 1 10 10 10 6 EF hand EF-hand_6 PF13405.6 PVD27840.1 - 1.4e-12 46.5 35.3 0.013 15.3 0.0 9.4 8 3 3 11 11 11 6 EF-hand domain EF-hand_8 PF13833.6 PVD27840.1 - 7.4e-12 44.9 21.4 0.043 13.7 0.0 7.3 6 2 2 8 8 8 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27840.1 - 0.00057 20.2 1.6 7 7.0 0.0 4.8 3 2 2 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region FcoT PF10862.8 PVD27840.1 - 0.043 13.4 0.0 2.2 7.9 0.0 2.8 3 0 0 3 3 3 0 FcoT-like thioesterase domain EF-hand_9 PF14658.6 PVD27840.1 - 0.14 12.5 0.5 34 4.9 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_4 PF12763.7 PVD27840.1 - 0.72 9.8 6.5 31 4.6 0.0 4.4 3 2 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand BSP_II PF05432.11 PVD27841.1 - 0.017 14.8 9.1 0.024 14.4 9.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.16 PVD27841.1 - 0.052 12.8 1.8 0.071 12.3 1.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNase_H2_suC PF08615.11 PVD27841.1 - 0.091 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4972 PF16342.5 PVD27841.1 - 0.096 12.4 2.1 0.17 11.6 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Radial_spoke PF04712.12 PVD27841.1 - 0.18 10.7 4.3 0.24 10.3 4.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein GRP PF07172.11 PVD27841.1 - 0.21 12.3 0.3 0.44 11.3 0.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family Myc_N PF01056.18 PVD27841.1 - 0.22 11.4 4.9 0.34 10.8 4.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Paf1 PF03985.13 PVD27841.1 - 0.59 9.1 6.4 0.84 8.6 6.4 1.3 1 0 0 1 1 1 0 Paf1 DUF2076 PF09849.9 PVD27841.1 - 1.2 9.1 4.6 1.7 8.6 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 PVD27841.1 - 3.4 5.7 11.1 5 5.1 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Spt5_N PF11942.8 PVD27841.1 - 5.2 8.1 13.6 8.4 7.4 13.6 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal EF-hand_1 PF00036.32 PVD27842.1 - 4.4e-14 50.9 4.1 0.00091 18.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD27842.1 - 1e-12 46.9 2.8 0.00026 20.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PVD27842.1 - 2.9e-12 46.8 2.2 8e-07 29.4 0.8 3.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD27842.1 - 1.2e-10 40.4 6.4 2e-05 23.9 0.2 4.3 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD27842.1 - 2.1e-08 33.9 0.6 0.0027 17.5 0.1 3.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 PVD27842.1 - 3.8e-05 23.5 0.7 0.01 15.7 0.1 2.8 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD27842.1 - 0.0011 19.3 0.1 1.2 9.5 0.2 3.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 PVD27842.1 - 0.18 11.7 1.1 17 5.3 0.1 2.2 2 0 0 2 2 2 0 Caleosin related protein EF-hand_6 PF13405.6 PVD27843.1 - 1.9e-11 42.9 1.6 0.0041 16.9 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PVD27843.1 - 3.2e-10 38.8 5.7 0.018 14.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD27843.1 - 4.2e-09 36.7 3.7 0.087 13.3 0.0 3.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD27843.1 - 6.9e-07 28.5 0.6 0.059 12.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PVD27843.1 - 0.00021 21.0 1.0 5.7 6.9 0.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27843.1 - 0.027 14.8 0.4 6.8 7.1 0.2 3.1 1 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region OATP PF03137.20 PVD27844.1 - 1e-111 373.9 13.6 4.3e-81 272.8 9.3 2.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD27844.1 - 4.8e-12 45.5 32.3 3.9e-07 29.3 7.5 4.1 3 2 1 4 4 4 3 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD27844.1 - 1.3e-06 28.4 12.3 4.7e-06 26.6 12.3 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD27844.1 - 0.066 13.2 8.6 0.2 11.7 8.6 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF1068 PF06364.12 PVD27844.1 - 1.5 8.7 3.6 4 7.3 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) EF-hand_1 PF00036.32 PVD27845.1 - 4.9e-18 63.3 35.7 0.0017 17.8 0.1 11.2 10 1 1 11 11 11 6 EF hand EF-hand_7 PF13499.6 PVD27845.1 - 7.9e-16 58.3 26.1 2.2e-05 24.8 0.5 8.3 3 3 3 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.6 PVD27845.1 - 1.9e-10 39.8 54.2 0.0052 16.6 0.1 13.0 12 3 3 15 15 15 6 EF-hand domain EF-hand_5 PF13202.6 PVD27845.1 - 2.8e-10 39.2 40.4 0.0008 18.8 0.1 10.6 11 1 1 12 12 12 4 EF hand SPARC_Ca_bdg PF10591.9 PVD27845.1 - 2e-05 24.9 6.6 31 4.9 0.1 7.4 4 2 2 7 7 7 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PVD27845.1 - 0.00017 21.4 25.4 1.5 8.7 0.5 8.9 8 2 2 10 10 10 3 EF-hand domain pair FcoT PF10862.8 PVD27845.1 - 0.0043 16.7 0.0 2.5 7.7 0.0 3.0 3 0 0 3 3 3 2 FcoT-like thioesterase domain DUF3911 PF13050.6 PVD27845.1 - 0.015 15.4 1.5 0.2 11.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3911) Fn_bind PF02986.14 PVD27845.1 - 0.11 12.3 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Fibronectin binding repeat EF-hand_6 PF13405.6 PVD27846.1 - 3.9e-13 48.2 9.8 0.00062 19.5 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 PVD27846.1 - 5e-13 47.6 10.7 0.00024 20.4 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 PVD27846.1 - 6.4e-12 44.4 10.8 0.00017 20.9 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD27846.1 - 7.2e-11 42.4 9.8 5e-06 26.9 1.0 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 PVD27846.1 - 7.9e-09 35.2 13.7 0.004 17.0 0.1 5.2 3 1 2 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD27846.1 - 0.044 14.1 0.3 15 5.9 0.1 2.8 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region SRCR PF00530.18 PVD27847.1 - 4e-23 81.8 6.5 9.6e-15 54.9 0.3 2.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27847.1 - 2.9e-05 24.6 0.0 0.0001 22.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27847.1 - 3.4e-05 24.1 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27847.1 - 0.00024 21.1 0.0 0.00062 19.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain SRCR_2 PF15494.6 PVD27847.1 - 0.0005 20.6 0.4 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain ig PF00047.25 PVD27847.1 - 0.0016 18.6 0.0 0.0051 17.0 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain DUF281 PF03436.13 PVD27847.1 - 2 8.9 5.6 2.7 8.5 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Rpr2 PF04032.16 PVD27849.1 - 0.06 13.6 1.3 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Rsbr_N PF08678.10 PVD27849.1 - 0.13 12.3 0.9 0.24 11.5 0.9 1.4 1 0 0 1 1 1 0 Rsbr N terminal SRCR PF00530.18 PVD27850.1 - 1.4e-16 60.8 0.2 4.3e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27850.1 - 1.5e-10 41.5 0.2 1.9e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD27850.1 - 4.7e-07 29.9 0.0 0.00098 19.2 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27850.1 - 2.7e-06 27.6 0.3 0.0071 16.7 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD27850.1 - 0.00032 20.7 0.0 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin I-set domain SRCR_2 PF15494.6 PVD27850.1 - 0.1 13.1 0.1 0.33 11.5 0.1 2.0 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PVD27851.1 - 3.3e-15 56.4 0.2 1.4e-08 35.1 0.1 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27851.1 - 3.1e-07 30.9 0.1 5.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD27851.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD27851.1 - 0.00016 21.8 0.0 0.00043 20.4 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27851.1 - 0.0007 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain NAD_binding_9 PF13454.6 PVD27851.1 - 0.03 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Integrase_H2C2 PF17921.1 PVD27852.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DMAP_binding PF06464.11 PVD27852.1 - 0.041 14.7 4.7 0.041 14.7 4.7 1.6 2 0 0 2 2 2 0 DMAP1-binding Domain Asp_protease_2 PF13650.6 PVD27852.1 - 0.12 13.0 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease PVL_ORF50 PF07768.11 PVD27852.1 - 0.15 12.4 3.0 0.28 11.5 3.0 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family ApoO PF09769.9 PVD27852.1 - 0.2 11.6 1.7 1.9 8.4 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein O DUF4337 PF14235.6 PVD27852.1 - 2.9 8.0 5.2 1.1 9.4 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) KfrA_N PF11740.8 PVD27852.1 - 3.1 8.5 10.9 1.6 9.5 7.1 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term LCD1 PF09798.9 PVD27852.1 - 3.8 5.9 4.8 5.2 5.5 4.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SRCR PF00530.18 PVD27853.1 - 1.5e-33 115.3 0.4 7.9e-12 45.6 0.0 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD27853.1 - 8.6e-30 103.2 6.3 4.3e-06 27.2 0.1 5.1 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD27853.1 - 4.9e-21 74.6 0.3 0.0015 18.6 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 PVD27853.1 - 2.1e-20 72.7 0.0 0.00015 21.8 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 PVD27853.1 - 1.5e-19 70.1 0.6 0.0047 17.2 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain MBG_2 PF18676.1 PVD27853.1 - 2.2e-05 25.0 0.1 33 5.2 0.0 4.7 4 0 0 4 4 4 0 MBG domain (YGX type) SRCR_2 PF15494.6 PVD27853.1 - 5e-05 23.8 0.1 0.73 10.4 0.0 3.3 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD27853.1 - 0.0042 17.2 2.5 24 5.2 0.1 5.8 5 3 0 5 5 5 0 Immunoglobulin V-set domain SP_C-Propep PF08999.10 PVD27853.1 - 0.088 12.6 0.1 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide Hepsin-SRCR PF09272.10 PVD27853.1 - 0.095 13.2 0.5 22 5.6 0.1 2.7 2 0 0 2 2 2 0 Hepsin, SRCR domain DUF530 PF04409.12 PVD27853.1 - 0.1 11.0 0.0 9.4 4.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF530) DUF2613 PF11021.8 PVD27853.1 - 7 6.9 8.3 18 5.5 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Ig_3 PF13927.6 PVD27854.1 - 5.1e-16 59.0 0.4 1.3e-06 28.9 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain SRCR PF00530.18 PVD27854.1 - 3.4e-15 56.4 0.0 8.7e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ig_2 PF13895.6 PVD27854.1 - 1.5e-11 44.5 0.9 5e-05 23.6 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD27854.1 - 2.2e-11 43.7 0.1 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD27854.1 - 1.6e-10 41.0 0.0 0.00043 20.4 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain SRCR_2 PF15494.6 PVD27854.1 - 0.0072 16.8 0.6 0.021 15.4 0.1 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain MBG_2 PF18676.1 PVD27854.1 - 0.0077 16.8 0.0 4.8 7.9 0.0 2.6 2 0 0 2 2 2 2 MBG domain (YGX type) Hepsin-SRCR PF09272.10 PVD27854.1 - 0.042 14.4 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Hepsin, SRCR domain Izumo-Ig PF16706.5 PVD27854.1 - 0.082 13.0 1.8 16 5.6 0.0 3.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain EphA2_TM PF14575.6 PVD27855.1 - 4.5e-05 24.2 0.0 0.045 14.6 0.0 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 PVD27855.1 - 0.00033 21.0 0.7 0.28 11.4 0.1 2.2 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator 7tm_1 PF00001.21 PVD27855.1 - 0.0064 15.8 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR19-TM PF15176.6 PVD27855.1 - 0.0092 16.0 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain SID-1_RNA_chan PF13965.6 PVD27855.1 - 0.012 14.0 1.7 1.9 6.8 0.1 2.0 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF2254 PF10011.9 PVD27855.1 - 0.017 13.9 0.2 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) OAD_gamma PF04277.13 PVD27855.1 - 0.022 15.4 0.2 0.022 15.4 0.2 2.3 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain O-antigen_lig PF13425.6 PVD27855.1 - 0.025 13.4 0.4 1.7 7.3 0.1 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein FAM176 PF14851.6 PVD27855.1 - 0.035 13.8 3.9 0.19 11.4 0.0 2.8 2 1 1 3 3 3 0 FAM176 family DUF443 PF04276.12 PVD27855.1 - 0.048 13.5 0.6 1.5 8.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) HemY_N PF07219.13 PVD27855.1 - 0.058 13.6 0.3 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 HemY protein N-terminus PEN-2 PF10251.9 PVD27855.1 - 0.065 13.7 0.7 0.092 13.2 0.0 1.5 2 0 0 2 2 1 0 Presenilin enhancer-2 subunit of gamma secretase LapA_dom PF06305.11 PVD27855.1 - 0.067 13.0 6.0 0.16 11.8 0.8 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2149 PF09919.9 PVD27855.1 - 0.068 13.4 2.0 0.55 10.5 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) AJAP1_PANP_C PF15298.6 PVD27855.1 - 0.078 13.2 1.3 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Serinc PF03348.15 PVD27855.1 - 0.097 11.6 0.1 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4446 PF14584.6 PVD27855.1 - 0.12 12.4 1.5 8.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Amnionless PF14828.6 PVD27855.1 - 0.15 10.9 0.1 4.1 6.1 0.0 2.0 2 0 0 2 2 2 0 Amnionless Sigma_reg_N PF13800.6 PVD27855.1 - 0.24 11.7 1.5 2 8.8 0.5 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DAG1 PF05454.11 PVD27855.1 - 0.33 10.3 3.1 5.6 6.3 0.8 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Baculo_11_kDa PF06143.11 PVD27855.1 - 3.3 7.4 5.6 6.7 6.4 2.8 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family I-set PF07679.16 PVD27856.1 - 2.7e-07 30.5 0.0 7.6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27856.1 - 2.6e-06 27.9 0.8 3.1e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD27856.1 - 3.9e-05 23.9 0.3 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD27856.1 - 0.0012 19.0 0.1 0.0047 17.1 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Syndecan PF01034.20 PVD27859.1 - 0.0037 17.2 0.1 0.0083 16.0 0.1 1.6 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 PVD27859.1 - 0.0065 17.3 0.2 0.013 16.4 0.2 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Glycoprotein_G PF00802.19 PVD27859.1 - 0.026 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Nudix_N PF12535.8 PVD27859.1 - 0.12 12.0 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal I-set PF07679.16 PVD27860.1 - 5.7e-09 35.9 5.9 2.8e-06 27.3 0.3 4.4 3 1 1 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD27860.1 - 2e-07 31.5 17.5 6.2e-07 29.9 0.4 4.8 5 0 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27860.1 - 1.2e-06 28.8 0.2 1.2e-06 28.8 0.2 4.9 4 1 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27860.1 - 0.00036 20.5 1.3 0.019 15.0 0.1 3.2 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain EphA2_TM PF14575.6 PVD27860.1 - 0.00053 20.8 0.1 0.00053 20.8 0.1 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Cytadhesin_P30 PF07271.11 PVD27860.1 - 0.0068 16.0 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 ig PF00047.25 PVD27860.1 - 0.014 15.6 0.3 0.014 15.6 0.3 4.9 5 0 0 5 5 5 0 Immunoglobulin domain Zip PF02535.22 PVD27860.1 - 0.069 12.3 1.3 0.13 11.4 1.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Syndecan PF01034.20 PVD27860.1 - 0.11 12.5 0.7 0.28 11.1 0.3 1.9 2 0 0 2 2 2 0 Syndecan domain Ig_6 PF18452.1 PVD27860.1 - 0.2 11.2 1.4 1.8 8.2 0.3 2.9 2 0 0 2 2 2 0 Immunoglobulin domain MAP17 PF15807.5 PVD27860.1 - 0.73 10.1 0.0 0.73 10.1 0.0 2.7 1 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 PVD27860.1 - 4.2 7.0 8.7 0.2 11.3 1.0 2.2 1 1 1 2 2 2 0 FAM176 family Ig_3 PF13927.6 PVD27861.1 - 5.4e-08 33.3 8.3 1.1e-05 25.9 1.2 4.7 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 PVD27861.1 - 5.3e-07 29.6 3.0 5e-06 26.5 0.3 3.5 4 0 0 4 4 4 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27861.1 - 9.2e-05 22.7 0.4 9.2e-05 22.7 0.4 4.1 4 1 1 5 5 5 1 Immunoglobulin domain UPF0051 PF01458.17 PVD27861.1 - 0.064 12.9 0.4 0.49 10.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein family (UPF0051) Ig_3 PF13927.6 PVD27862.1 - 3.2e-10 40.4 13.5 1.4e-06 28.8 1.0 4.8 4 1 1 5 5 5 3 Immunoglobulin domain I-set PF07679.16 PVD27862.1 - 6.7e-10 38.9 1.2 2.3e-05 24.4 0.1 3.9 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD27862.1 - 4.9e-07 30.0 13.5 7.6e-07 29.4 0.3 4.7 4 1 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 PVD27862.1 - 2.3e-05 24.5 12.9 0.012 15.7 0.3 5.5 5 1 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD27862.1 - 8.5e-05 22.5 0.3 0.049 13.7 0.0 3.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD27863.1 - 7.9e-12 45.6 15.7 1.7e-08 34.9 1.2 3.9 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD27863.1 - 2.4e-11 43.5 2.5 1.6e-07 31.3 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 PVD27863.1 - 1.2e-08 35.0 9.7 2.9e-05 24.2 0.1 4.6 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD27863.1 - 9.7e-08 32.2 14.6 4.7e-06 26.8 0.5 4.7 3 2 1 4 4 4 2 Immunoglobulin domain EphA2_TM PF14575.6 PVD27863.1 - 0.0012 19.7 0.1 0.0029 18.4 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 PVD27863.1 - 0.004 16.0 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Amnionless C2-set_2 PF08205.12 PVD27863.1 - 0.0049 16.9 2.5 0.61 10.2 0.4 3.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD27863.1 - 0.023 14.9 9.7 0.11 12.7 0.6 5.0 4 2 0 4 4 4 0 Immunoglobulin V-set domain S1FA PF04689.13 PVD27863.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA CYYR1 PF10873.8 PVD27863.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.7 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Exo_endo_phos_2 PF14529.6 PVD27864.1 - 5.7e-08 32.6 0.2 9.1e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD27864.1 - 6.4e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH_2 PF17919.1 PVD27865.1 - 3.4e-30 104.0 0.0 1e-29 102.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD27865.1 - 4.9e-25 87.8 0.0 1.2e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD27865.1 - 7e-24 84.6 0.0 1.4e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PVD27865.1 - 9.6e-20 71.0 0.0 2.2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 PVD27865.1 - 6.8e-16 58.1 0.6 1.4e-15 57.1 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD27865.1 - 0.0004 20.5 0.5 0.00097 19.3 0.5 1.7 1 0 0 1 1 1 1 H2C2 zinc finger ClpB_D2-small PF10431.9 PVD27865.1 - 0.16 12.0 0.3 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein IMUP PF15761.5 PVD27865.1 - 0.18 12.5 3.0 0.38 11.5 3.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Ank_2 PF12796.7 PVD27866.1 - 7.1e-20 71.4 0.1 1.7e-09 38.1 0.0 5.6 5 2 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD27866.1 - 5.9e-14 52.2 3.0 0.018 15.6 0.3 7.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD27866.1 - 9.7e-10 38.6 2.9 3.3e-09 36.9 2.9 2.0 1 0 0 1 1 1 1 SOCS box Ank_3 PF13606.6 PVD27866.1 - 2.4e-09 36.6 2.8 0.0053 17.1 0.0 8.2 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 PVD27866.1 - 2.7e-07 30.7 11.4 0.0031 17.9 0.1 7.8 9 1 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 PVD27866.1 - 4.1e-05 23.8 6.0 2 8.9 0.2 6.9 6 2 1 8 8 8 1 Ankyrin repeats (many copies) Arrestin_N PF00339.29 PVD27867.1 - 3.1e-22 79.2 0.0 1.3e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD27867.1 - 1.9e-19 70.4 0.0 4e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD27867.1 - 0.00024 20.4 0.2 0.0033 16.7 0.1 2.2 2 0 0 2 2 2 1 Rgp1 Vps26 PF03643.15 PVD27867.1 - 0.0041 16.2 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 OTCace PF00185.24 PVD27868.1 - 2.2e-51 174.0 0.0 3.8e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 PVD27868.1 - 1.5e-34 119.2 0.0 7.1e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain EF-hand_2 PF09068.11 PVD27869.1 - 6.3e-41 139.4 0.1 1.5e-40 138.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 PVD27869.1 - 8.8e-40 135.0 0.0 2.5e-39 133.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 PVD27869.1 - 1.4e-16 60.0 5.9 3e-16 59.0 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type WW PF00397.26 PVD27869.1 - 7.7e-08 32.3 0.3 1.3e-07 31.6 0.3 1.4 1 0 0 1 1 1 1 WW domain Spectrin PF00435.21 PVD27869.1 - 5.8e-07 30.0 3.8 5.8e-07 30.0 3.8 3.4 2 1 0 2 2 2 1 Spectrin repeat C1_2 PF03107.16 PVD27869.1 - 6.4e-05 23.2 4.3 0.00016 21.9 4.3 1.6 1 0 0 1 1 1 1 C1 domain 4HB_MCP_1 PF12729.7 PVD27869.1 - 0.0082 15.7 7.6 0.018 14.6 3.4 2.5 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction Miff PF05644.11 PVD27869.1 - 0.013 15.1 6.8 0.023 14.3 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff SOGA PF11365.8 PVD27869.1 - 0.026 15.6 14.1 1.2 10.3 6.2 3.9 2 1 3 5 5 4 0 Protein SOGA bZIP_1 PF00170.21 PVD27869.1 - 0.035 14.2 12.4 0.16 12.1 4.7 3.0 3 0 0 3 3 2 0 bZIP transcription factor HALZ PF02183.18 PVD27869.1 - 0.13 12.5 12.1 1.9 8.8 2.6 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 PVD27869.1 - 0.17 12.1 19.7 0.035 14.3 12.4 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1319 PF07028.11 PVD27869.1 - 0.31 11.3 3.4 3.7 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) FPP PF05911.11 PVD27869.1 - 0.63 8.1 14.8 0.46 8.6 10.7 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 PVD27869.1 - 0.77 9.6 15.9 0.32 10.8 3.8 3.6 3 0 0 3 3 3 0 Septum formation initiator Sipho_Gp157 PF05565.11 PVD27869.1 - 1.8 8.5 7.2 8.8 6.3 0.4 3.0 3 0 0 3 3 3 0 Siphovirus Gp157 DUF5082 PF16888.5 PVD27869.1 - 2.5 8.4 12.4 8.6 6.7 2.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF3958 PF13125.6 PVD27869.1 - 2.9 8.2 12.9 0.32 11.2 5.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) KASH_CCD PF14662.6 PVD27869.1 - 3.3 7.5 17.1 2.5 7.9 11.4 3.0 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 PVD27869.1 - 4.5 8.0 16.2 3.1 8.5 3.9 3.4 2 1 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 PVD27869.1 - 4.7 7.5 16.2 70 3.7 13.0 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 PVD27869.1 - 5.7 6.2 12.3 1.4 8.2 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 PVD27869.1 - 9.5 6.6 15.3 0.28 11.5 3.6 3.0 3 0 0 3 3 2 0 TSC-22/dip/bun family Spectrin PF00435.21 PVD27870.1 - 2.6e-163 532.5 251.2 1.6e-13 51.0 8.7 22.5 21 1 1 22 22 22 22 Spectrin repeat CH PF00307.31 PVD27870.1 - 3.1e-25 88.5 0.2 4.5e-20 71.9 0.0 3.8 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF2935 PF11155.8 PVD27870.1 - 4.7e-07 30.2 22.5 3.9 7.8 0.0 13.3 9 6 1 10 10 10 2 Domain of unknown function (DUF2935) CAMSAP_CH PF11971.8 PVD27870.1 - 5.9e-05 22.8 0.0 0.00018 21.2 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain CLZ PF16526.5 PVD27870.1 - 0.00064 20.0 1.8 0.00064 20.0 1.8 16.5 16 5 4 20 20 20 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SchA_CurD PF04486.12 PVD27870.1 - 0.093 12.8 0.7 5.6 7.1 0.0 3.4 2 0 0 2 2 2 0 SchA/CurD like domain BRCT_assoc PF12820.7 PVD27870.1 - 1.2 8.9 12.0 1.7 8.4 0.1 4.8 5 0 0 5 5 5 0 Serine-rich domain associated with BRCT DUF725 PF05267.12 PVD27870.1 - 1.6 8.7 5.2 3.2 7.8 0.1 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF725) SNF2_N PF00176.23 PVD27871.1 - 1.3e-55 188.5 0.1 7.7e-55 186.0 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 PVD27871.1 - 2.4e-09 37.4 0.0 6e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CUE PF02845.16 PVD27871.1 - 4.9e-06 26.1 0.1 0.011 15.4 0.1 2.9 2 0 0 2 2 2 2 CUE domain DEAD PF00270.29 PVD27871.1 - 9.4e-06 25.5 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.7 PVD27871.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HDA2-3 PF11496.8 PVD27871.1 - 0.059 12.5 0.7 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 PET PF06297.14 PVD27871.1 - 0.073 13.4 0.5 0.37 11.1 0.1 2.4 2 0 0 2 2 2 0 PET Domain DIL PF01843.19 PVD27871.1 - 0.092 13.0 0.3 0.092 13.0 0.3 3.4 4 0 0 4 4 4 0 DIL domain HHH PF00633.23 PVD27871.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_C2 PF00648.21 PVD27872.1 - 6e-08 32.1 0.0 3e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Calpain family cysteine protease Globin PF00042.22 PVD27872.1 - 1e-05 26.0 0.1 0.17 12.4 0.0 2.5 2 0 0 2 2 2 2 Globin IQ PF00612.27 PVD27872.1 - 7.2e-05 22.2 1.4 0.00021 20.8 1.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif CDC45 PF02724.14 PVD27872.1 - 4.2 5.5 6.8 12 4.0 6.8 1.8 1 0 0 1 1 1 0 CDC45-like protein CEP209_CC5 PF16574.5 PVD27873.1 - 3.5e-38 130.7 19.7 3.5e-38 130.7 19.7 19.5 10 7 9 21 21 21 1 Coiled-coil region of centrosome protein CE290 KASH_CCD PF14662.6 PVD27873.1 - 0.0032 17.3 26.4 0.0032 17.3 26.4 20.2 5 3 15 21 21 21 3 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 PVD27873.1 - 0.0075 16.7 26.4 0.0075 16.7 26.4 18.2 1 1 10 11 11 11 4 Fez1 TSC22 PF01166.18 PVD27873.1 - 0.05 13.9 0.1 0.05 13.9 0.1 25.2 27 5 5 32 32 32 0 TSC-22/dip/bun family MtrG PF04210.13 PVD27873.1 - 0.34 10.8 1.1 44 4.0 0.2 4.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LRR_8 PF13855.6 PVD27875.1 - 8.7e-72 236.8 87.3 1.2e-13 50.6 5.5 13.1 6 3 8 14 14 14 12 Leucine rich repeat LRR_4 PF12799.7 PVD27875.1 - 3.4e-36 122.7 80.8 1.5e-05 25.2 3.1 15.2 15 1 1 16 16 16 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD27875.1 - 7.5e-23 80.9 0.1 6.2e-08 32.7 0.2 4.2 4 0 0 4 4 4 3 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 PVD27875.1 - 8.4e-19 68.0 0.0 1.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD27875.1 - 1.3e-14 54.8 0.0 3.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD27875.1 - 3.4e-11 43.0 30.0 0.00063 19.3 1.3 8.1 2 2 7 10 10 10 6 Leucine-rich repeat LRR_1 PF00560.33 PVD27875.1 - 0.00038 20.6 61.2 0.18 12.5 0.8 16.1 16 2 0 16 16 16 3 Leucine Rich Repeat FNIP PF05725.12 PVD27875.1 - 0.005 17.0 0.6 0.2 11.9 0.5 3.6 3 1 0 3 3 3 1 FNIP Repeat DUF1863 PF08937.11 PVD27875.1 - 0.094 13.0 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_8 PF13855.6 PVD27876.1 - 4.6e-98 321.0 80.4 2.9e-16 59.0 2.8 13.1 8 5 7 15 15 15 14 Leucine rich repeat LRR_4 PF12799.7 PVD27876.1 - 7.7e-51 169.2 60.2 1.2e-05 25.5 1.2 14.5 11 1 1 13 13 13 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD27876.1 - 2.2e-30 105.2 0.1 1.3e-07 31.6 0.0 6.9 4 1 2 7 7 7 4 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 PVD27876.1 - 1.9e-20 73.4 0.5 4.4e-20 72.2 0.5 1.6 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD27876.1 - 4.2e-17 62.8 0.1 1e-16 61.6 0.1 1.7 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD27876.1 - 2e-16 58.0 58.4 6.6 7.7 0.0 19.8 20 0 0 20 20 20 5 Leucine Rich Repeat LRR_9 PF14580.6 PVD27876.1 - 3.7e-08 33.1 24.6 0.38 10.2 0.2 7.9 3 2 5 9 9 9 6 Leucine-rich repeat DUF1863 PF08937.11 PVD27876.1 - 0.00048 20.5 0.4 0.0014 19.0 0.4 1.7 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRRNT PF01462.18 PVD27876.1 - 0.17 11.6 11.1 0.11 12.2 1.2 4.5 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PVD27876.1 - 3 8.1 0.0 3 8.1 0.0 16.1 20 0 0 20 20 20 0 Leucine Rich repeat DUF4096 PF13340.6 PVD27877.1 - 0.00014 22.0 16.9 0.18 12.0 0.4 4.4 1 1 6 7 7 7 7 Putative transposase of IS4/5 family (DUF4096) DUF4219 PF13961.6 PVD27877.1 - 0.0035 17.0 16.0 1.7e+02 2.0 0.0 9.3 10 0 0 10 10 10 0 Domain of unknown function (DUF4219) RFC1 PF08519.12 PVD27877.1 - 0.92 9.7 16.8 5.5 7.1 2.2 5.0 1 1 3 4 4 4 0 Replication factor RFC1 C terminal domain DUF4573 PF15140.6 PVD27879.1 - 2.8e-05 24.0 0.0 0.00024 20.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) PTS_EIIB PF00367.20 PVD27879.1 - 0.028 13.9 11.6 10 5.7 0.2 5.2 2 2 4 6 6 6 0 phosphotransferase system, EIIB Caskin1-CID PF16600.5 PVD27879.1 - 0.068 13.7 14.9 3.7 8.2 0.7 4.6 1 1 1 2 2 2 0 Caskin1 CASK-interaction domain LSM14 PF12701.7 PVD27879.1 - 0.29 11.3 4.4 11 6.2 0.8 2.7 1 1 1 2 2 2 0 Scd6-like Sm domain NMT1_3 PF16868.5 PVD27879.1 - 0.54 9.6 3.3 1.5 8.2 0.5 2.1 1 1 1 2 2 2 0 NMT1-like family Galactosyl_T PF01762.21 PVD27881.1 - 3e-42 144.7 0.0 4.1e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase TssN PF17555.2 PVD27881.1 - 0.078 12.3 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2593 PF10767.9 PVD27881.1 - 0.096 12.8 1.1 0.21 11.7 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Fringe PF02434.16 PVD27881.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Fringe-like MMS22L_N PF14910.6 PVD27882.1 - 2.7e-54 184.8 9.1 4e-48 164.4 2.7 2.9 2 1 1 3 3 3 2 S-phase genomic integrity recombination mediator, N-terminal MMS22L_C PF14911.6 PVD27882.1 - 4.9e-33 114.7 0.6 9.2e-33 113.8 0.2 1.7 2 0 0 2 2 2 1 S-phase genomic integrity recombination mediator, C-terminal COesterase PF00135.28 PVD27883.1 - 1.8e-133 446.1 0.0 2.2e-133 445.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD27883.1 - 0.00011 22.1 1.5 0.00065 19.6 1.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold INCENP_ARK-bind PF03941.15 PVD27884.1 - 1.7e-19 69.5 1.3 1.7e-19 69.5 1.3 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region RVT_1 PF00078.27 PVD27885.1 - 2.4e-27 95.9 0.0 4.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_2 PF08356.12 PVD27885.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 EF hand associated Exo_endo_phos PF03372.23 PVD27885.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD27885.1 - 0.093 12.6 0.2 0.33 10.8 0.2 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD27886.1 - 0.00061 19.4 0.7 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 PVD27887.1 - 5.3e-58 195.2 0.5 6.6e-58 194.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD27887.1 - 1.8e-19 70.1 0.0 3.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD27887.1 - 9.3e-11 41.5 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD27887.1 - 0.00013 21.6 0.1 0.00031 20.3 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD27887.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD27887.1 - 0.00075 19.1 0.3 0.0015 18.0 0.3 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 PVD27887.1 - 0.0019 18.0 2.5 0.012 15.4 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 PVD27887.1 - 0.085 12.8 4.3 2.9 7.8 0.2 2.3 1 1 0 2 2 2 0 RsgA GTPase Adaptin_N PF01602.20 PVD27888.1 - 4.9e-113 378.4 6.0 7.1e-113 377.9 6.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 PVD27888.1 - 3e-59 198.6 1.3 7.2e-59 197.4 0.1 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 PVD27888.1 - 2e-58 196.3 0.1 5.5e-58 194.8 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 PVD27888.1 - 3.1e-10 39.4 0.4 0.021 15.1 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 PVD27888.1 - 6.7e-10 39.2 4.4 6.1e-06 26.4 0.1 4.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD27888.1 - 2.3e-08 34.3 0.3 0.028 14.8 0.0 5.1 3 3 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 PVD27888.1 - 1.5e-06 28.5 0.7 0.54 10.8 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat MMS19_N PF14500.6 PVD27888.1 - 0.00013 21.7 0.5 0.24 11.0 0.0 3.2 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 PVD27888.1 - 0.0037 17.2 0.8 3.2 7.9 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat SAD_SRA PF02182.17 PVD27889.1 - 9.7e-55 184.6 0.0 1.7e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain CUB PF00431.20 PVD27890.1 - 1.5e-37 128.3 0.1 4.1e-22 78.6 0.1 2.5 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 PVD27890.1 - 8.8 6.6 18.1 1.3 9.3 5.4 3.1 2 1 1 3 3 3 0 Low-density lipoprotein receptor domain class A Ank_2 PF12796.7 PVD27891.1 - 0.0048 17.5 0.2 1.3 9.6 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD27891.1 - 0.0053 17.2 0.1 12 6.8 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat CAP_GLY PF01302.25 PVD27892.1 - 1.8e-12 47.1 0.2 3.8e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain XhlA PF10779.9 PVD27892.1 - 1.6 9.0 9.3 0.22 11.7 3.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA ZapB PF06005.12 PVD27892.1 - 8.8 6.8 38.2 0.057 13.9 4.4 4.7 4 0 0 4 4 4 0 Cell division protein ZapB E1_DerP2_DerF2 PF02221.15 PVD27893.1 - 2.3e-14 54.0 0.2 3.1e-14 53.6 0.2 1.1 1 0 0 1 1 1 1 ML domain zf_CCCH_4 PF18345.1 PVD27893.1 - 0.17 12.0 1.8 6 7.1 0.0 2.7 3 0 0 3 3 3 0 Zinc finger domain Lectin_C PF00059.21 PVD27895.1 - 1.6e-18 67.4 0.9 2.2e-18 66.9 0.6 1.4 1 1 0 1 1 1 1 Lectin C-type domain CAP_N PF01213.19 PVD27895.1 - 0.002 17.6 1.9 0.0025 17.4 1.9 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PknG_rubred PF16919.5 PVD27895.1 - 0.02 15.1 0.6 0.026 14.7 0.1 1.5 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Mito_fiss_reg PF05308.11 PVD27895.1 - 0.058 13.5 3.4 0.076 13.1 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD27895.1 - 0.1 12.6 7.2 0.19 11.8 7.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM171 PF15471.6 PVD27895.1 - 1.1 8.2 3.5 1.6 7.7 3.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Androgen_recep PF02166.16 PVD27895.1 - 3.3 6.5 4.6 5.2 5.8 4.6 1.2 1 0 0 1 1 1 0 Androgen receptor Lectin_C PF00059.21 PVD27897.1 - 1.2e-51 173.9 4.5 3.3e-17 63.2 0.7 3.2 3 0 0 3 3 3 3 Lectin C-type domain RVT_1 PF00078.27 PVD27897.1 - 4e-17 62.5 0.0 6.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UL45 PF05473.12 PVD27897.1 - 0.00067 19.4 3.4 0.061 13.0 0.1 2.4 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27898.1 - 3.4e-19 69.6 2.9 1.7e-10 41.6 0.1 2.4 2 1 1 3 3 3 2 Lectin C-type domain UL45 PF05473.12 PVD27898.1 - 0.00053 19.7 0.1 0.0007 19.3 0.1 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Bac_chlorC PF02043.17 PVD27898.1 - 0.11 12.5 0.6 8.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Lectin_C PF00059.21 PVD27899.1 - 1.3e-16 61.3 0.2 1.8e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27899.1 - 0.00014 21.5 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27900.1 - 6.8e-16 58.9 0.0 1.2e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27900.1 - 0.00034 20.3 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27901.1 - 6e-15 55.9 0.1 9.1e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27901.1 - 5.3e-06 26.2 0.2 8.9e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like BRO1 PF03097.18 PVD27901.1 - 0.00012 21.1 0.0 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Lectin_C PF00059.21 PVD27902.1 - 3.6e-16 59.8 0.1 8.5e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD27903.1 - 1.8e-20 73.7 0.4 2.3e-20 73.3 0.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27903.1 - 0.00035 20.3 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27904.1 - 1.1e-06 29.4 0.0 1.3e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD27905.1 - 2.4e-15 57.2 0.1 3.9e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27905.1 - 0.0026 17.4 0.5 0.0026 17.4 0.5 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD27906.1 - 5.8e-14 52.7 0.7 8.5e-14 52.2 0.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27906.1 - 0.00033 20.4 0.1 0.00048 19.8 0.1 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 PVD27906.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 PVD27907.1 - 5.2e-29 101.2 0.3 6.8e-13 49.3 0.0 2.9 3 1 0 3 3 3 2 Lectin C-type domain UL45 PF05473.12 PVD27907.1 - 2.2 7.9 8.8 0.037 13.7 1.4 2.0 2 2 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like 7tm_3 PF00003.22 PVD27908.1 - 1.5e-47 162.3 12.8 2.6e-47 161.6 12.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD27908.1 - 9.3e-35 120.4 0.1 5.1e-20 71.9 0.1 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD27908.1 - 0.0066 16.2 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 Periplasmic binding protein Lectin_C PF00059.21 PVD27910.1 - 6.1e-08 33.4 3.8 9.2e-08 32.8 3.8 1.3 1 1 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 PVD27911.1 - 9.6e-42 141.8 2.9 3.4e-14 53.1 0.1 4.7 5 0 0 5 5 5 4 CUB domain Ldl_recept_a PF00057.18 PVD27911.1 - 0.00035 20.7 8.4 0.00035 20.7 8.4 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD27912.1 - 1.4e-07 31.8 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 CUB domain CTD PF12815.7 PVD27919.1 - 0.032 14.8 18.7 0.36 11.4 18.9 2.1 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 PT PF04886.12 PVD27920.1 - 1.1e-08 34.5 17.6 2.2e-08 33.5 17.6 1.5 1 0 0 1 1 1 1 PT repeat Yae1_N PF09811.9 PVD27921.1 - 7.2e-06 25.6 6.6 1.1e-05 25.0 6.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Peptidase_C78 PF07910.13 PVD27922.1 - 3.9e-24 85.3 0.0 6.3e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 LRR_6 PF13516.6 PVD27923.1 - 1.1e-12 46.9 5.0 0.55 10.4 0.0 6.8 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 PVD27923.1 - 2.7e-08 33.9 4.0 0.00044 20.6 0.1 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD27923.1 - 0.00052 20.2 7.6 14 6.7 2.1 5.6 3 3 0 3 3 3 2 Leucine Rich Repeat ArfGap PF01412.18 PVD27924.1 - 2.4e-30 105.0 1.0 2.4e-30 105.0 1.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RA PF00788.23 PVD27925.1 - 4.1e-39 133.1 0.0 3.1e-19 69.4 0.0 3.3 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 PVD27925.1 - 6e-33 113.2 1.6 6e-33 113.2 1.6 2.1 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 PVD27925.1 - 1.6e-16 60.4 0.4 1.6e-16 60.4 0.4 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PVD27925.1 - 3.4e-10 39.6 0.3 1.3e-09 37.7 0.2 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD27925.1 - 2.9e-06 27.5 0.1 9.2e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain FHA PF00498.26 PVD27925.1 - 0.00015 22.0 0.0 0.00046 20.5 0.0 1.9 1 0 0 1 1 1 1 FHA domain CUB PF00431.20 PVD27926.1 - 4e-15 56.1 0.0 6.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 CUB domain 7tm_1 PF00001.21 PVD27927.1 - 3.5e-07 29.8 17.5 5.3e-07 29.2 17.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD27927.1 - 1.5e-05 24.5 20.3 0.00073 19.0 6.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD27927.1 - 0.0019 17.9 14.5 0.0085 15.7 14.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-CCHC PF00098.23 PVD27929.1 - 1.9e-10 40.3 16.0 2e-05 24.4 5.3 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 PVD27929.1 - 0.0015 18.2 6.2 0.2 11.4 0.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 PVD27929.1 - 0.01 15.6 8.7 0.18 11.7 1.9 3.0 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 PVD27929.1 - 0.78 10.1 8.9 0.44 10.9 0.7 3.0 3 0 0 3 3 3 0 DnaJ central domain NTP_transf_7 PF07984.12 PVD27930.1 - 2e-159 530.0 3.5 2.5e-159 529.7 3.5 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Myb_DNA-binding PF00249.31 PVD27930.1 - 0.0007 19.7 0.9 0.0069 16.6 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD27930.1 - 0.073 13.3 1.2 0.27 11.5 0.1 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain Transket_pyr PF02779.24 PVD27932.1 - 1.5e-42 145.3 0.0 2.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PVD27932.1 - 1.4e-32 112.2 0.0 3e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain ATE_C PF04377.15 PVD27933.1 - 1.2e-49 168.3 0.6 2.2e-49 167.5 0.6 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 PVD27933.1 - 2e-25 89.0 1.0 4.1e-25 88.0 1.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus LIAS_N PF16881.5 PVD27933.1 - 0.24 11.8 1.0 19 5.7 0.1 2.7 2 1 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family BTB PF00651.31 PVD27934.1 - 2.1e-33 114.9 0.7 4e-16 59.2 0.0 3.9 3 1 1 4 4 4 3 BTB/POZ domain BACK PF07707.15 PVD27934.1 - 0.022 14.8 0.0 0.093 12.8 0.0 2.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch TFIID-31kDa PF02291.15 PVD27934.1 - 0.07 13.2 0.1 0.66 10.1 0.0 2.4 2 1 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RCC1_2 PF13540.6 PVD27934.1 - 0.081 12.8 0.5 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat SPECT1 PF18680.1 PVD27934.1 - 1.7 8.2 5.2 0.6 9.7 0.8 2.3 3 0 0 3 3 3 0 Plasmodium host cell traversal SPECT1 Hist_deacetyl PF00850.19 PVD27935.1 - 7.9e-82 275.2 0.0 1.1e-81 274.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HMG_box PF00505.19 PVD27936.1 - 1.7e-21 76.4 19.4 1.1e-13 51.4 1.5 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD27936.1 - 2.7e-16 59.9 12.2 5.4e-10 39.7 4.9 2.5 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 PVD27936.1 - 9.9e-05 23.0 9.7 0.0067 17.0 0.3 3.1 1 1 2 3 3 3 2 YABBY protein Ndc80_HEC PF03801.13 PVD27937.1 - 1.6e-46 157.8 0.0 3.6e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 PVD27937.1 - 3.8e-13 49.3 0.4 3.8e-13 49.3 0.4 4.9 4 2 0 5 5 5 1 Domain of unknown function (DUF5595) GAS PF13851.6 PVD27937.1 - 1 8.6 47.3 0.031 13.6 13.8 3.7 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding HpcH_HpaI PF03328.14 PVD27938.1 - 2.7e-47 160.7 0.1 3.4e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 PVD27938.1 - 1.1e-08 34.6 0.3 9.8e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3755 PF12579.8 PVD27938.1 - 0.02 14.5 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) CRAL_TRIO_2 PF13716.6 PVD27939.1 - 1.3e-39 135.5 2.9 2.5e-39 134.6 2.9 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 PVD27939.1 - 2.4e-35 121.6 0.1 4.2e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 PVD27939.1 - 4.2e-08 33.1 1.7 1.3e-07 31.5 1.7 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain Lipocalin_2 PF08212.12 PVD27940.1 - 2.5e-20 72.9 0.0 3.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 PVD27940.1 - 3.8e-15 56.4 0.0 4.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 PVD27940.1 - 0.0024 17.4 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 PVD27940.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Triabin DUF4371 PF14291.6 PVD27943.1 - 2e-05 24.3 0.6 0.00013 21.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) Viral_alk_exo PF01771.17 PVD27943.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral alkaline exonuclease DUF668 PF05003.12 PVD27943.1 - 0.068 13.6 1.5 0.42 11.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF668) SAG PF04092.13 PVD27943.1 - 1.8 9.4 5.0 2.6 8.8 1.0 2.8 2 1 0 2 2 2 0 SRS domain Pentapeptide_4 PF13599.6 PVD27945.1 - 5.8e-11 42.4 48.4 0.00083 19.5 1.7 11.5 5 4 4 9 9 9 6 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 PVD27945.1 - 0.068 12.8 0.0 62 3.4 0.0 5.9 7 0 0 7 7 7 0 Pentapeptide repeats (8 copies) Transposase_28 PF04195.12 PVD27945.1 - 0.72 10.1 6.0 8.7 6.7 0.1 5.9 5 0 0 5 5 5 0 Putative gypsy type transposon 7tm_3 PF00003.22 PVD27946.1 - 2.5e-25 89.6 7.7 4e-23 82.4 1.5 2.1 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR PhoLip_ATPase_C PF16212.5 PVD27946.1 - 0.2 11.4 6.9 0.061 13.1 2.9 1.8 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal ANF_receptor PF01094.28 PVD27947.1 - 3.3e-53 181.1 3.7 4.9e-53 180.5 3.7 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD27947.1 - 1.1e-15 58.2 0.0 2.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Periplasmic binding protein Peptidase_M20 PF01546.28 PVD27947.1 - 2.3e-09 37.2 0.4 4.7e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PVD27947.1 - 0.0032 17.4 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain ANF_receptor PF01094.28 PVD27948.1 - 1.5e-53 182.2 1.6 2.1e-53 181.7 1.6 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD27948.1 - 2e-41 142.3 16.1 4e-41 141.3 16.1 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 PVD27948.1 - 3.5e-09 36.8 0.0 7.4e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein ACT_7 PF13840.6 PVD27948.1 - 0.00028 20.6 2.5 0.00073 19.3 0.0 2.7 3 0 0 3 3 3 1 ACT domain ISPD_C PF18706.1 PVD27948.1 - 0.017 14.8 1.3 3.4 7.3 0.5 2.4 2 0 0 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF2231 PF09990.9 PVD27948.1 - 0.1 13.1 5.9 0.054 13.9 2.8 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Atrophin-1 PF03154.15 PVD27950.1 - 4.6 5.4 8.0 4.7 5.4 8.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family Presenilin PF01080.17 PVD27950.1 - 7.9 5.1 6.0 8.6 5.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin Tiam_CC_Ex PF18385.1 PVD27952.1 - 4.9e-37 126.2 0.0 1.4e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain RhoGEF PF00621.20 PVD27952.1 - 2.2e-34 119.3 4.7 4.2e-34 118.4 4.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PVD27952.1 - 2.4e-17 63.3 0.4 1.6e-14 54.3 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 PVD27952.1 - 2.7e-11 43.9 0.0 6.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RBD PF02196.15 PVD27952.1 - 4.5e-09 36.2 0.0 1.4e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Raf-like Ras-binding domain PDZ PF00595.24 PVD27952.1 - 5.3e-08 33.1 0.1 7e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PVD27952.1 - 2.1e-07 30.7 0.0 5.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD27952.1 - 0.00037 20.8 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 PVD27952.1 - 0.00087 19.7 0.3 0.1 13.0 0.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain TUG-UBL1 PF11470.8 PVD27952.1 - 0.0082 16.4 0.0 0.034 14.4 0.0 2.1 1 0 0 1 1 1 1 TUG ubiquitin-like domain BIR PF00653.21 PVD27954.1 - 1.6e-21 76.7 3.0 2.9e-16 59.9 0.3 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain BIR PF00653.21 PVD27955.1 - 6.3e-31 106.8 1.5 4.2e-15 56.1 0.5 3.0 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD27955.1 - 2.9e-10 39.9 9.2 2.9e-10 39.9 9.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD27955.1 - 0.00078 19.2 10.4 0.0027 17.5 10.4 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Hormone_recep PF00104.30 PVD27956.1 - 1.9e-29 102.7 0.0 2.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PLDc_2 PF13091.6 PVD27957.1 - 6.5e-15 55.2 0.5 1.7e-09 37.7 0.2 3.3 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PVD27957.1 - 1.8e-14 53.2 0.7 9.5e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 PVD27957.1 - 1.8e-12 47.2 8.3 1.2e-10 41.3 2.8 3.3 3 1 0 3 3 3 2 PX domain PH PF00169.29 PVD27957.1 - 0.0034 17.9 1.8 0.015 15.8 0.2 2.9 2 1 0 2 2 2 1 PH domain SAGA-Tad1 PF12767.7 PVD27957.1 - 0.25 11.1 5.7 1.1 9.0 5.7 2.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Tetraspanin PF00335.20 PVD27958.1 - 3.6e-53 180.6 27.0 7e-46 156.8 9.7 2.1 2 0 0 2 2 2 2 Tetraspanin family DUF5316 PF17247.2 PVD27958.1 - 0.00055 19.9 4.8 0.57 10.2 0.4 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5316) RNA_pol_N PF01194.17 PVD27958.1 - 0.044 14.1 0.2 11 6.4 0.0 2.9 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Glyco_transf_36 PF06165.11 PVD27960.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 36 7tm_1 PF00001.21 PVD27961.1 - 0.0033 16.8 0.7 0.0037 16.6 0.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD27961.1 - 0.0068 15.8 0.9 0.0087 15.5 0.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ABC2_membrane_2 PF12679.7 PVD27961.1 - 0.012 14.9 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TM_GPCR_Srx PF10328.9 PVD27961.1 - 0.02 14.5 4.0 0.025 14.2 4.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srx PF10328.9 PVD27963.1 - 1.4e-05 24.8 2.2 1.6e-05 24.7 2.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD27963.1 - 0.0012 18.2 1.4 0.0014 18.0 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD27963.1 - 0.0021 17.4 1.7 0.0025 17.2 1.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD27963.1 - 0.018 14.7 1.8 0.023 14.4 1.8 1.3 1 1 0 1 1 1 0 Srg family chemoreceptor Serpentine_r_xa PF03383.15 PVD27963.1 - 0.12 12.4 2.0 0.14 12.1 2.0 1.1 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Lectin_C PF00059.21 PVD27964.1 - 2.7e-17 63.5 0.3 3.6e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27964.1 - 2.2e-05 24.2 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like LSR PF05624.14 PVD27964.1 - 0.0044 17.0 1.8 0.0082 16.1 1.8 1.4 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) Lectin_C PF00059.21 PVD27965.1 - 1.6e-15 57.8 0.0 3.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD27965.1 - 0.0014 18.3 0.2 0.0023 17.6 0.2 1.6 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like LSR PF05624.14 PVD27965.1 - 0.0028 17.6 1.3 0.0058 16.6 1.3 1.5 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) Mrpl_C PF18502.1 PVD27965.1 - 0.045 14.0 0.1 0.17 12.2 0.0 1.8 1 1 1 2 2 2 0 54S ribosomal protein L8 C-terminal domain P5CR_dimer PF14748.6 PVD27965.1 - 0.14 12.4 0.3 1.2 9.5 0.3 2.2 1 1 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Lon_2 PF13337.6 PVD27965.1 - 0.21 10.1 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease 7TM_GPCR_Srx PF10328.9 PVD27966.1 - 9.5e-06 25.4 0.4 1.1e-05 25.2 0.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD27966.1 - 0.00074 18.9 0.3 0.00093 18.6 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD27966.1 - 0.0051 16.2 0.6 0.006 15.9 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD27966.1 - 0.012 15.3 0.3 0.014 15.1 0.3 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srt PF10321.9 PVD27966.1 - 0.062 12.3 1.4 0.077 12.0 1.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt MBT PF02820.18 PVD27967.1 - 1.3e-53 179.2 0.0 1.8e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 mbt repeat SLED PF12140.8 PVD27967.1 - 6.5e-37 126.5 0.2 1.1e-36 125.8 0.2 1.3 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 PVD27967.1 - 1.4e-11 44.6 0.3 2.5e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD27967.1 - 2.1e-05 24.5 0.1 5e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD27967.1 - 0.0077 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Med14 PF08638.11 PVD27968.1 - 5.6e-64 215.1 0.5 2.9e-63 212.7 0.1 2.3 2 0 0 2 2 2 1 Mediator complex subunit MED14 Apc13p PF05839.11 PVD27968.1 - 1.8e-12 47.3 1.3 3.8e-12 46.2 1.3 1.6 1 0 0 1 1 1 1 Apc13p protein Ldl_recept_a PF00057.18 PVD27969.1 - 3e-05 24.1 2.9 3e-05 24.1 2.9 3.1 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD27969.1 - 0.00023 21.5 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 CUB domain Lectin_C PF00059.21 PVD27969.1 - 0.00032 21.4 0.0 0.00083 20.1 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain PRKCSH-like PF12999.7 PVD27969.1 - 0.69 9.7 6.1 1.9 8.3 6.1 1.7 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CUB PF00431.20 PVD27970.1 - 3.1e-10 40.4 0.0 8.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 PVD27971.1 - 2.2e-07 31.2 0.1 5.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 PVD27971.1 - 5e-07 29.8 11.4 7.2e-05 22.9 4.3 3.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD27971.1 - 0.0033 18.1 0.0 0.0091 16.7 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD27972.1 - 1.3e-11 45.1 0.0 4.6e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Lectin C-type domain CUB PF00431.20 PVD27972.1 - 1.1e-07 32.2 0.1 0.00014 22.2 0.0 3.3 3 0 0 3 3 3 1 CUB domain Ldl_recept_a PF00057.18 PVD27972.1 - 1e-06 28.8 30.4 0.0031 17.7 4.4 4.4 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Fer4_15 PF13459.6 PVD27972.1 - 5.4 7.8 7.6 26 5.7 0.5 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain BIR PF00653.21 PVD27973.1 - 1.1e-40 138.1 3.8 2.4e-22 79.4 1.4 3.2 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD27973.1 - 4.8e-12 45.6 12.9 4.8e-12 45.6 12.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD27973.1 - 5.2e-05 23.0 14.4 5.8e-05 22.9 12.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD27973.1 - 0.044 13.7 16.2 0.14 12.0 16.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4241 PF14025.6 PVD27973.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) zf-RING_UBOX PF13445.6 PVD27973.1 - 0.69 10.0 8.8 0.9 9.6 7.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 PVD27973.1 - 1.2 9.1 18.9 0.12 12.3 13.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain ABC_membrane PF00664.23 PVD27974.1 - 2.1e-71 240.8 36.1 1.4e-40 139.7 5.8 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD27974.1 - 6e-51 172.6 5.3 2e-28 99.6 0.0 3.8 3 0 0 3 3 3 2 ABC transporter RsgA_GTPase PF03193.16 PVD27974.1 - 5.3e-07 29.7 0.3 9.8e-05 22.3 0.1 2.8 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PVD27974.1 - 6.8e-06 26.1 0.2 0.046 13.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD27974.1 - 0.00021 21.0 0.5 0.095 12.5 0.1 3.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 PVD27974.1 - 0.0032 17.2 0.1 0.05 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD27974.1 - 0.013 15.9 5.4 0.74 10.2 0.1 3.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_10 PF12846.7 PVD27974.1 - 0.05 12.5 0.3 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 PVD27974.1 - 0.055 13.0 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PVD27974.1 - 0.065 12.1 2.0 0.45 9.4 0.1 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FKBP_N_2 PF18023.1 PVD27974.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 BDBT FKBP like N-terminal DUF87 PF01935.17 PVD27974.1 - 0.18 11.9 0.0 0.18 11.9 0.0 4.6 5 0 0 5 5 5 0 Helicase HerA, central domain AAA_22 PF13401.6 PVD27974.1 - 0.2 11.9 7.1 3.3 8.0 0.0 4.6 4 1 0 4 4 4 0 AAA domain LapA_dom PF06305.11 PVD27974.1 - 0.27 11.1 2.6 1.3 8.8 0.4 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AAA_23 PF13476.6 PVD27974.1 - 0.99 9.9 11.9 8.9 6.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain RBD PF02196.15 PVD27975.1 - 2.8e-06 27.3 10.5 42 4.3 0.0 9.9 4 4 3 8 8 8 5 Raf-like Ras-binding domain HrpB7 PF09486.10 PVD27977.1 - 3.5 8.0 8.4 47 4.3 0.5 3.5 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) MIG-14_Wnt-bd PF06664.12 PVD27978.1 - 9.4e-96 320.5 35.1 9.4e-96 320.5 35.1 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion HEAT_EZ PF13513.6 PVD27979.1 - 8.3e-05 23.0 0.1 0.073 13.6 0.0 2.9 2 0 0 2 2 2 2 HEAT-like repeat DUF5066 PF16728.5 PVD27979.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) HEAT_2 PF13646.6 PVD27979.1 - 0.066 13.6 0.6 16 6.0 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 PVD27979.1 - 1.3 9.4 8.5 8 7.0 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat zf-C4pol PF14260.6 PVD27980.1 - 0.2 12.1 0.0 0.4 11.2 0.0 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Glyco_hydro_3 PF00933.21 PVD27981.1 - 5e-43 147.7 0.0 3.5e-41 141.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 PVD27981.1 - 4.4e-41 141.1 0.0 6.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 PVD27981.1 - 2.4e-13 50.0 0.8 9.3e-13 48.1 0.7 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 PVD27981.1 - 0.085 13.2 8.9 0.89 9.9 5.1 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF11 Glyco_hydro_3_C PF01915.22 PVD27982.1 - 1.3e-44 152.7 0.0 2e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PVD27982.1 - 1.5e-38 132.9 0.0 9.2e-19 67.9 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 PVD27982.1 - 2.5e-14 53.1 0.5 5.5e-14 52.0 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 PVD27982.1 - 0.062 13.6 6.3 0.32 11.3 6.3 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF11 Creatinase_N_2 PF16189.5 PVD27983.1 - 6.9e-45 153.0 0.4 3.3e-44 150.8 0.1 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 PVD27983.1 - 1.9e-39 135.5 0.0 2.9e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 PVD27983.1 - 9.1e-19 67.3 2.2 2e-18 66.2 2.2 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PVD27983.1 - 4.2e-15 56.6 0.0 2.4e-11 44.4 0.0 2.6 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Malic_M PF03949.15 PVD27984.1 - 8e-97 323.5 0.2 1.9e-96 322.3 0.1 1.6 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 PVD27984.1 - 3.5e-82 274.6 0.0 5.2e-82 274.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mito_carr PF00153.27 PVD27985.1 - 2.3e-64 213.3 0.2 2.1e-23 82.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SDF PF00375.18 PVD27985.1 - 0.086 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Tropomyosin_1 PF12718.7 PVD27986.1 - 0.001 19.2 16.0 0.001 19.2 16.0 5.3 3 2 2 5 5 5 2 Tropomyosin like AAA_13 PF13166.6 PVD27986.1 - 0.44 9.1 51.5 2.8 6.5 17.2 2.4 1 1 1 2 2 2 0 AAA domain WD40_alt PF14077.6 PVD27986.1 - 2.7 7.9 9.0 11 5.9 0.3 3.4 3 1 0 3 3 3 0 Alternative WD40 repeat motif MFS_1 PF07690.16 PVD27987.1 - 5.1e-29 101.3 44.5 1.4e-19 70.2 27.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD27987.1 - 3.4e-07 29.9 3.8 3.4e-07 29.9 3.8 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2160 PF09928.9 PVD27987.1 - 8.8 6.7 8.2 1.6 9.1 1.7 2.6 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2160) Glyco_hydro_3 PF00933.21 PVD27988.1 - 1.8e-46 159.0 0.0 5.1e-46 157.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 PVD27988.1 - 3.3e-40 138.2 0.0 5.1e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 PVD27988.1 - 5.4e-07 29.6 0.2 1.2e-06 28.6 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Big_3_5 PF16640.5 PVD27988.1 - 0.21 11.8 2.2 0.97 9.7 0.1 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Glyco_hydro_3_C PF01915.22 PVD27989.1 - 2.3e-39 135.5 0.0 3.6e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 PVD27989.1 - 3.2e-10 40.0 0.5 6e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Big_3_5 PF16640.5 PVD27989.1 - 0.081 13.1 2.5 0.24 11.6 0.5 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF11 PF01345.18 PVD27989.1 - 3.9 7.8 8.4 2.4 8.5 6.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF11 Sporozoite_P67 PF05642.11 PVD27990.1 - 0.015 13.5 5.0 0.017 13.2 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HgmA PF04209.13 PVD27992.1 - 2.6e-219 728.2 0.0 7.9e-219 726.6 0.0 1.7 2 0 0 2 2 2 1 homogentisate 1,2-dioxygenase GMC_oxred_C PF05199.13 PVD27992.1 - 2e-17 64.0 0.5 6.5e-10 39.7 0.1 2.6 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 PVD27992.1 - 3.8e-11 42.9 0.0 5.5e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase DUF4071 PF13281.6 PVD27993.1 - 1.1e-143 478.7 0.1 1.9e-142 474.7 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 PVD27993.1 - 4.1e-67 226.3 0.0 8.1e-67 225.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD27993.1 - 2.4e-43 148.3 0.0 4.6e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD27993.1 - 0.0023 16.8 0.1 0.0081 15.0 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PVD27993.1 - 0.0043 16.6 0.1 0.0099 15.4 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 PVD27993.1 - 0.035 13.4 0.1 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like TPR_11 PF13414.6 PVD27993.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 TPR repeat CARD PF00619.21 PVD27994.1 - 4.9e-12 45.7 4.5 7.1e-12 45.2 1.0 3.2 3 0 0 3 3 3 1 Caspase recruitment domain CARD_2 PF16739.5 PVD27994.1 - 1e-07 31.8 0.4 1.9e-06 27.7 0.1 3.3 3 0 0 3 3 3 1 Caspase recruitment domain SUB1_ProdP9 PF18213.1 PVD27994.1 - 0.091 12.6 0.0 0.41 10.5 0.0 2.1 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EGF_CA PF07645.15 PVD27995.1 - 0.0011 19.2 10.5 0.14 12.4 2.3 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 PVD27995.1 - 0.0063 16.7 6.9 0.5 10.6 0.1 2.5 2 0 0 2 2 2 2 EGF domain hEGF PF12661.7 PVD27995.1 - 0.038 14.6 15.5 0.18 12.5 2.3 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF cEGF PF12662.7 PVD27995.1 - 0.064 13.2 7.8 0.73 9.8 0.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD27995.1 - 0.068 13.5 10.8 0.06 13.6 1.5 2.4 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD27995.1 - 0.099 13.0 13.1 2 8.8 2.4 2.6 2 0 0 2 2 2 0 EGF-like domain Herpes_UL31 PF02718.14 PVD27995.1 - 0.12 11.4 0.2 0.19 10.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL31-like protein RhoGEF PF00621.20 PVD27996.1 - 1.6e-08 35.0 0.0 2.1e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 RhoGEF domain SEN1_N PF12726.7 PVD27996.1 - 0.015 13.5 0.2 0.016 13.4 0.2 1.1 1 0 0 1 1 1 0 SEN1 N terminal Pro_isomerase PF00160.21 PVD27997.1 - 9.2e-38 130.0 0.0 1.7e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PVD27997.1 - 5.7e-16 58.1 0.2 2.9e-15 55.8 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hva1_TUDOR PF11160.8 PVD27997.1 - 2.3 8.5 4.6 0.76 10.0 0.7 2.3 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain H_lectin PF09458.10 PVD27998.1 - 4.2e-15 55.7 0.1 8e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 H-type lectin domain Glyco_hydro_3 PF00933.21 PVD28000.1 - 1.1e-12 48.0 0.0 1.2e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain TAFA PF12020.8 PVD28000.1 - 0.046 14.2 0.1 0.066 13.7 0.1 1.3 1 0 0 1 1 1 0 TAFA family H_lectin PF09458.10 PVD28001.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 H-type lectin domain CtIP_N PF10482.9 PVD28001.1 - 0.004 17.2 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain HALZ PF02183.18 PVD28001.1 - 0.012 15.9 0.5 0.04 14.2 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 PVD28001.1 - 0.033 14.4 0.1 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 PVD28001.1 - 0.042 14.2 0.2 12 6.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 PVD28001.1 - 0.045 14.1 0.1 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 PVD28001.1 - 0.074 13.5 0.2 3.4 8.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF717 PF05338.12 PVD28001.1 - 0.079 13.1 1.1 21 5.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF717) DUF35_N PF12172.8 PVD28001.1 - 0.088 12.7 0.1 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Nnf1 PF03980.14 PVD28001.1 - 0.1 13.0 1.7 2 8.8 0.2 2.2 1 1 1 2 2 2 0 Nnf1 Snapin_Pallidin PF14712.6 PVD28001.1 - 0.11 13.0 0.5 1.4 9.4 0.2 2.2 2 0 0 2 2 2 0 Snapin/Pallidin bZIP_1 PF00170.21 PVD28001.1 - 0.15 12.2 2.0 0.3 11.2 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF3138 PF11336.8 PVD28001.1 - 0.37 9.3 0.7 0.61 8.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) CDI PF02234.19 PVD28003.1 - 2.8e-09 37.0 0.2 8.3e-09 35.5 0.2 1.9 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor EB PF01683.18 PVD28006.1 - 8.2e-08 32.4 18.1 0.00022 21.5 7.3 2.2 1 1 1 2 2 2 2 EB module Mdv1 PF11542.8 PVD28006.1 - 0.17 11.9 1.0 3.9 7.5 0.1 2.5 3 0 0 3 3 3 0 Mitochondrial division protein 1 Dickkopf_N PF04706.12 PVD28006.1 - 0.97 10.0 16.4 0.36 11.3 7.9 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region TIL PF01826.17 PVD28006.1 - 9.7 6.5 17.6 0.27 11.5 6.3 2.4 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain WD40 PF00400.32 PVD28007.1 - 2.9e-13 50.1 12.7 2e-06 28.4 0.1 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 PVD28007.1 - 0.00015 20.6 5.7 0.0085 14.8 0.1 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Biopterin_H PF00351.21 PVD28010.1 - 7.5e-163 541.3 0.2 9e-163 541.0 0.2 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_7 PF13499.6 PVD28011.1 - 4.8e-18 65.4 6.8 2.3e-11 44.0 0.1 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD28011.1 - 3.2e-14 51.3 3.1 0.00042 19.7 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD28011.1 - 2.7e-13 48.7 0.6 0.00085 19.1 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PVD28011.1 - 1.2e-06 28.2 3.1 0.00016 21.4 0.0 3.5 2 1 2 4 4 4 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 PVD28011.1 - 0.00084 19.4 2.9 0.0093 16.0 0.0 3.4 3 1 1 4 4 4 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 PVD28011.1 - 0.01 16.2 0.3 3.9 7.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain DUF3859 PF12975.7 PVD28011.1 - 0.067 13.2 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3859) SPARC_Ca_bdg PF10591.9 PVD28011.1 - 0.07 13.5 0.4 0.87 9.9 0.0 2.6 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 PVD28011.1 - 0.088 12.3 0.0 0.088 12.3 0.0 2.8 3 1 1 4 4 4 0 EF hand Ras PF00071.22 PVD28012.1 - 1.7e-55 187.0 0.0 2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28012.1 - 8e-31 106.8 0.0 1.2e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28012.1 - 2.8e-17 62.7 0.0 3.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD28012.1 - 8.1e-09 35.2 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD28012.1 - 3.1e-05 24.0 0.0 4.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD28012.1 - 0.035 14.0 0.0 2.3 8.1 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase ABC_sub_bind PF04392.12 PVD28012.1 - 0.26 10.5 0.0 0.36 10.0 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Bcl-2 PF00452.19 PVD28013.1 - 4.7e-08 33.6 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family PRIMA1 PF16101.5 PVD28013.1 - 3 7.9 5.9 6.7 6.8 5.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Bcl-2 PF00452.19 PVD28014.1 - 0.00015 22.4 0.6 0.0006 20.4 0.0 2.4 3 0 0 3 3 3 1 Apoptosis regulator proteins, Bcl-2 family HBB PF06777.11 PVD28014.1 - 0.048 13.3 0.3 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Helical and beta-bridge domain Ribosomal_L17 PF01196.19 PVD28014.1 - 0.43 11.5 1.9 1.2 10.1 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L17 Ribosomal_L23 PF00276.20 PVD28015.1 - 2.9e-09 37.2 0.1 4.8e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Toprim PF01751.22 PVD28015.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Toprim domain WD40 PF00400.32 PVD28016.1 - 1.7e-11 44.4 18.3 0.066 14.1 0.2 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28016.1 - 3.1e-08 33.8 0.0 0.0015 18.8 0.0 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 PVD28017.1 - 8.3e-06 25.7 0.1 1.7e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 PVD28018.1 - 5.2e-11 42.3 2.5 5.2e-11 42.3 2.5 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CCDC144C PF14915.6 PVD28018.1 - 0.072 12.2 0.4 0.096 11.8 0.4 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ANTH PF07651.16 PVD28019.1 - 1.1e-78 264.1 0.0 1.4e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 PVD28019.1 - 8.6e-12 45.2 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain APG6_N PF17675.1 PVD28019.1 - 3.4 8.2 8.0 18 5.8 8.0 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region H_lectin PF09458.10 PVD28020.1 - 0.00034 20.8 0.0 0.00054 20.1 0.0 1.3 1 0 0 1 1 1 1 H-type lectin domain RhoGAP PF00620.27 PVD28022.1 - 3.5e-18 65.9 0.0 5.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain NicO PF03824.16 PVD28022.1 - 1.8 7.8 14.2 3.5 6.9 14.2 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 PVD28022.1 - 3.4 7.0 27.7 1.5 8.2 23.1 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Dpy19 PF10034.9 PVD28023.1 - 6.2e-208 692.1 10.1 7.2e-208 691.9 10.1 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation TMEM40 PF15817.5 PVD28023.1 - 1.6 8.5 6.9 1 9.1 0.2 3.0 3 0 0 3 3 3 0 Transmembrane protein 40 family WD40 PF00400.32 PVD28024.1 - 6.8e-54 178.6 24.4 5.8e-07 30.1 0.5 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28024.1 - 2.2e-20 72.7 1.1 8.6e-05 22.8 0.0 7.6 2 2 7 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PVD28024.1 - 5.6e-15 55.6 1.9 1.3e-14 54.4 1.9 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 PVD28024.1 - 8.3e-09 34.8 0.3 1.4 7.8 0.0 6.8 2 2 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PVD28024.1 - 2.9e-07 30.1 0.2 0.076 12.3 0.0 3.5 3 0 0 3 3 3 3 WD40-like domain Nup160 PF11715.8 PVD28024.1 - 0.017 13.8 4.2 1.8 7.1 0.1 4.8 5 2 1 6 6 6 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 PVD28024.1 - 0.091 11.7 0.2 8.4 5.2 0.0 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 PVD28024.1 - 0.12 12.3 0.0 9.1 6.4 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat ANF_receptor PF01094.28 PVD28025.1 - 1.2e-40 139.7 0.2 4.8e-38 131.2 0.2 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 PVD28025.1 - 2.4e-37 128.1 0.0 5.8e-37 126.8 0.0 1.7 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD28025.1 - 5.5e-31 107.1 0.0 1.2e-30 106.0 0.0 1.6 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD28025.1 - 1.9e-22 79.8 0.0 9e-22 77.6 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 PVD28025.1 - 5e-16 58.4 2.4 5.4e-16 58.3 0.9 1.9 2 0 0 2 2 2 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.6 PVD28025.1 - 1.4e-11 44.7 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.16 PVD28025.1 - 0.019 14.9 0.7 0.055 13.4 0.7 1.8 1 0 0 1 1 1 0 Ion channel DUF2390 PF09523.10 PVD28025.1 - 0.05 13.9 2.0 0.12 12.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Hydrolase_6 PF13344.6 PVD28026.1 - 4.5e-25 87.7 0.1 2.9e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD28026.1 - 2.8e-13 49.7 0.0 5.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PVD28026.1 - 2.7e-07 30.8 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD28026.1 - 3.6e-05 24.2 0.0 0.00015 22.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 PVD28026.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) TilS PF09179.11 PVD28027.1 - 0.013 15.9 0.6 0.013 15.9 0.6 2.5 3 0 0 3 3 3 0 TilS substrate binding domain Androgen_recep PF02166.16 PVD28027.1 - 0.37 9.6 4.3 0.52 9.1 4.3 1.1 1 0 0 1 1 1 0 Androgen receptor Ldl_recept_a PF00057.18 PVD28028.1 - 0.00043 20.4 5.8 0.00084 19.5 5.8 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A adh_short PF00106.25 PVD28029.1 - 5.8e-49 166.2 0.0 7.6e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD28029.1 - 2.3e-32 112.4 0.0 3.1e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD28029.1 - 4.8e-14 52.7 0.1 7.5e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD28029.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 PVD28029.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 PVD28029.1 - 0.048 13.5 0.2 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 PVD28030.1 - 1.7e-62 211.0 0.0 2.1e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD28030.1 - 7e-52 175.7 0.2 9.3e-52 175.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD28030.1 - 6.6e-12 45.7 0.1 9.7e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 KR domain C_GCAxxG_C_C PF09719.10 PVD28030.1 - 0.023 15.0 0.1 0.051 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) PID PF00640.23 PVD28032.1 - 1.1e-18 67.6 1.2 1.5e-18 67.2 0.8 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 PVD28032.1 - 1e-13 51.6 0.4 1.7e-13 50.8 0.4 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD28032.1 - 2.1e-06 27.9 0.1 4.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain A_thal_3526 PF09713.10 PVD28032.1 - 0.033 14.5 0.5 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) ATP-cone PF03477.16 PVD28032.1 - 0.082 13.5 0.0 2.2 8.9 0.0 2.4 2 0 0 2 2 2 0 ATP cone domain HLH PF00010.26 PVD28035.1 - 6.4e-18 64.5 0.7 1.3e-17 63.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 PVD28039.1 - 2e-17 62.9 1.1 3.1e-17 62.3 1.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Topoisom_bac PF01131.20 PVD28039.1 - 0.07 12.1 0.1 0.091 11.7 0.1 1.1 1 0 0 1 1 1 0 DNA topoisomerase Cas9-BH PF16593.5 PVD28039.1 - 0.18 11.6 1.3 0.34 10.7 1.3 1.4 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Rpr2 PF04032.16 PVD28040.1 - 1.4 9.3 7.4 0.52 10.6 5.1 1.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HLH PF00010.26 PVD28042.1 - 4.9e-20 71.2 1.0 4.9e-20 71.2 1.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Voldacs PF03517.13 PVD28042.1 - 0.00095 19.3 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF3824 PF12868.7 PVD28045.1 - 0.063 13.9 4.8 0.8 10.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4695 PF15766.5 PVD28046.1 - 2.3e-08 34.2 0.2 3.5e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4695) RCC1 PF00415.18 PVD28047.1 - 1.6e-68 227.2 23.5 2.1e-11 44.3 0.0 8.6 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD28047.1 - 4.1e-46 153.9 23.7 4.6e-09 35.8 1.5 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 PVD28047.1 - 2.8e-06 26.8 0.0 1.1e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD28047.1 - 3.1e-06 26.8 0.0 7.8e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 PVD28048.1 - 8.9e-54 182.6 0.0 5.2e-53 180.1 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD28048.1 - 2.8e-20 72.7 0.0 1e-19 70.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD28048.1 - 0.003 16.4 0.0 0.0065 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD28048.1 - 0.0036 17.2 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD28048.1 - 0.0067 15.8 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD28048.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PVD28048.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PVD28048.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family eIF2_C PF09173.11 PVD28049.1 - 5.5e-37 125.9 2.4 6.2e-37 125.7 0.4 2.1 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 PVD28049.1 - 1.9e-22 79.7 0.3 1.7e-21 76.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PVD28049.1 - 1.2e-12 48.0 0.4 3.1e-12 46.7 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 PVD28049.1 - 7.9e-05 22.6 0.5 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PVD28049.1 - 0.0049 16.9 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 PVD28049.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Peptidase_M50 PF02163.22 PVD28050.1 - 2.7e-15 56.3 0.0 3.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 FtsX PF02687.21 PVD28050.1 - 1.4 9.4 6.4 3.4 8.2 0.4 2.4 2 0 0 2 2 2 0 FtsX-like permease family DUF948 PF06103.11 PVD28053.1 - 0.082 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Macoilin PF09726.9 PVD28054.1 - 8.4e-214 712.0 50.6 8.9e-213 708.6 50.6 1.9 1 1 0 1 1 1 1 Macoilin family PKcGMP_CC PF16808.5 PVD28054.1 - 0.0042 16.9 1.5 0.0042 16.9 1.5 4.3 3 1 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 PVD28054.1 - 0.0056 16.1 36.6 0.029 13.7 22.8 2.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 PVD28054.1 - 0.01 15.8 8.5 0.01 15.8 8.5 5.2 5 1 0 5 5 5 0 TATA element modulatory factor 1 DNA binding RskA PF10099.9 PVD28054.1 - 0.041 14.2 6.6 4.6 7.5 0.1 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CENP-F_leu_zip PF10473.9 PVD28054.1 - 0.18 11.9 33.6 0.56 10.2 10.9 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 PVD28054.1 - 0.19 11.5 31.3 0.17 11.7 0.8 3.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2613 PF11021.8 PVD28054.1 - 0.78 9.9 6.6 2.5 8.3 6.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF3040 PF11239.8 PVD28054.1 - 1.4 9.3 3.8 1.2e+02 3.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Lzipper-MIP1 PF14389.6 PVD28054.1 - 9.7 6.6 37.2 3 8.2 2.8 6.1 3 2 3 6 6 6 0 Leucine-zipper of ternary complex factor MIP1 Cpn60_TCP1 PF00118.24 PVD28055.1 - 3.4e-152 507.5 11.6 3.9e-152 507.3 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RAG1_imp_bd PF12560.8 PVD28056.1 - 0.012 15.2 0.2 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 RAG1 importin binding DGCR6 PF07324.11 PVD28057.1 - 1.7e-27 96.3 3.3 3e-26 92.3 0.4 1.9 1 1 1 2 2 2 2 DiGeorge syndrome critical region 6 (DGCR6) protein TMEM247 PF15444.6 PVD28057.1 - 0.35 10.9 3.7 7 6.6 0.6 2.0 1 1 1 2 2 2 0 Transmembrane protein 247 LicD PF04991.13 PVD28058.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 LicD family GST_C PF00043.25 PVD28059.1 - 0.00019 21.6 0.1 0.00084 19.5 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD28059.1 - 0.00039 20.5 0.1 0.003 17.7 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD28059.1 - 0.042 13.9 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 PVD28059.1 - 0.071 13.0 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TPR_14 PF13428.6 PVD28060.1 - 2.3e-05 24.8 4.2 0.2 12.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD28060.1 - 0.014 15.6 3.2 0.74 10.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD28060.1 - 0.037 13.8 2.8 14 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 PVD28060.1 - 0.043 12.8 1.2 0.38 9.7 0.2 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 PVD28060.1 - 0.053 13.8 17.1 1 9.6 1.2 4.9 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PVD28060.1 - 0.11 12.8 16.7 0.37 11.1 1.0 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28060.1 - 0.11 13.0 1.4 8.3 7.0 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD28060.1 - 0.15 12.2 19.0 0.49 10.6 0.0 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD28060.1 - 0.18 12.1 4.1 2 8.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD28060.1 - 0.32 11.7 3.5 2.3 8.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3H1 PF10650.9 PVD28062.1 - 6.8e-09 35.3 1.6 1.6e-08 34.1 1.6 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_14 PF13428.6 PVD28062.1 - 9.2e-05 22.9 2.6 2.5 9.2 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD28062.1 - 0.00022 21.1 2.5 11 6.5 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28062.1 - 0.00035 21.0 1.4 0.026 15.0 0.1 4.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD28062.1 - 0.0021 18.3 6.1 13 6.2 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD28062.1 - 0.025 14.6 0.3 30 4.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD28062.1 - 0.034 14.3 0.0 33 5.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD28062.1 - 0.41 10.8 9.9 2.9 8.1 0.6 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD28062.1 - 4.2 8.0 5.0 61 4.3 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Neprosin_AP PF14365.6 PVD28063.1 - 0.058 13.9 0.1 0.077 13.5 0.1 1.2 1 0 0 1 1 1 0 Neprosin activation peptide Spond_N PF06468.13 PVD28064.1 - 1.7e-73 246.9 0.4 3.4e-73 245.9 0.4 1.5 1 0 0 1 1 1 1 Spondin_N Reeler PF02014.16 PVD28064.1 - 3.4e-16 60.2 0.2 1.2e-15 58.4 0.0 1.9 2 0 0 2 2 2 1 Reeler domain TSP_1 PF00090.19 PVD28064.1 - 8.2e-15 54.8 19.2 6.8e-10 39.0 5.0 3.4 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF3592 PF12158.8 PVD28064.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF5330 PF17264.2 PVD28064.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5330) SNAD4 PF18750.1 PVD28064.1 - 0.46 10.6 2.1 1.8 8.7 0.1 2.6 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 Kunitz_BPTI PF00014.23 PVD28065.1 - 3e-19 69.0 6.1 3e-19 69.0 6.1 2.5 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TSP_1 PF00090.19 PVD28065.1 - 1e-18 67.2 29.0 2.3e-12 46.9 10.3 4.3 2 1 2 4 4 4 2 Thrombospondin type 1 domain Squash PF00299.18 PVD28065.1 - 0.042 13.9 6.5 0.3 11.2 6.5 2.6 1 0 0 1 1 1 0 Squash family serine protease inhibitor Glyco_transf_41 PF13844.6 PVD28065.1 - 0.7 8.3 10.4 0.91 7.9 10.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 IQ PF00612.27 PVD28066.1 - 0.0016 18.1 1.0 0.0035 17.0 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif HTH_22 PF13309.6 PVD28066.1 - 0.068 13.3 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 HTH domain LANC_like PF05147.13 PVD28067.1 - 1.9e-20 72.8 0.0 1.3e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Voltage_CLC PF00654.20 PVD28067.1 - 0.051 12.8 0.6 5.8 6.0 0.3 2.1 2 0 0 2 2 2 0 Voltage gated chloride channel DUF3585 PF12130.8 PVD28068.1 - 5.7e-41 139.8 14.6 5.7e-41 139.8 14.6 3.4 3 0 0 3 3 3 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 PVD28068.1 - 1.4e-19 70.3 0.0 3.6e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD28068.1 - 2.5e-08 33.6 0.0 7.3e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain FAD_binding_3 PF01494.19 PVD28068.1 - 2.1e-05 24.0 0.0 5.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 PVD28068.1 - 0.00032 19.9 0.0 0.0006 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD28068.1 - 0.00062 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD28068.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD28068.1 - 0.0051 15.6 0.2 0.016 14.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein LIM PF00412.22 PVD28068.1 - 0.052 13.8 6.6 0.11 12.8 6.6 1.5 1 0 0 1 1 1 0 LIM domain FAD_oxidored PF12831.7 PVD28068.1 - 0.12 11.7 1.5 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PVD28068.1 - 0.14 12.4 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thioredoxin_16 PF18569.1 PVD28068.1 - 0.15 12.2 0.2 0.5 10.5 0.2 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain FAD_binding_3 PF01494.19 PVD28069.1 - 4.2e-07 29.5 0.1 6.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PVD28069.1 - 3.6e-05 23.2 0.4 5.6e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD28069.1 - 5.3e-05 22.5 0.2 8.2e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD28069.1 - 6.6e-05 22.3 0.2 0.00018 20.8 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD28069.1 - 0.0035 16.1 0.2 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 PVD28069.1 - 0.01 16.4 0.1 0.03 14.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PVD28069.1 - 0.013 14.8 0.4 0.02 14.3 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 PVD28069.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 PVD28069.1 - 0.074 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 PVD28069.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 PVD28069.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3585 PF12130.8 PVD28070.1 - 1.6e-26 93.0 24.1 1.6e-26 93.0 24.1 2.6 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 PVD28070.1 - 3e-13 49.9 0.0 1e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.22 PVD28070.1 - 2e-05 24.7 5.6 5.2e-05 23.4 5.6 1.7 1 0 0 1 1 1 1 LIM domain CAMSAP_CH PF11971.8 PVD28070.1 - 0.0014 18.5 0.0 0.0041 16.9 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain DUF1885 PF08968.10 PVD28070.1 - 0.0038 17.3 0.8 0.0038 17.3 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1885) HIT PF01230.23 PVD28071.1 - 1.8e-13 51.1 0.0 4.1e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 PVD28071.1 - 6e-11 42.8 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DENN PF02141.21 PVD28072.1 - 3.1e-53 180.5 1.5 6.4e-53 179.5 1.5 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 PVD28072.1 - 4.3e-25 88.2 3.5 7.1e-22 77.8 0.6 3.3 3 0 0 3 3 3 2 RUN domain dDENN PF03455.19 PVD28072.1 - 1.3e-16 60.3 0.4 1.3e-16 60.3 0.4 2.2 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 PVD28072.1 - 5e-13 49.6 0.0 1.5e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain PLAT PF01477.23 PVD28072.1 - 2.3e-11 44.3 0.0 4.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain VWC PF00093.18 PVD28073.1 - 2.3e-179 581.8 763.3 1.2e-11 44.8 14.2 34.5 33 1 1 34 34 34 30 von Willebrand factor type C domain VWD PF00094.25 PVD28073.1 - 1.4e-34 119.7 0.8 2.7e-34 118.7 0.2 1.8 2 0 0 2 2 2 1 von Willebrand factor type D domain TILa PF12714.7 PVD28073.1 - 2.6e-34 116.9 544.4 9.9e-05 22.2 7.7 34.2 31 2 1 33 33 33 26 TILa domain Vault PF01505.18 PVD28073.1 - 0.13 12.5 0.5 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Major Vault Protein repeat domain Kunitz_BPTI PF00014.23 PVD28074.1 - 1e-31 108.9 28.4 9.1e-18 64.2 8.4 3.7 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Tyrosinase PF00264.20 PVD28074.1 - 5.7e-27 95.5 8.0 1.9e-18 67.6 3.4 3.5 2 1 0 2 2 2 2 Common central domain of tyrosinase EGF PF00008.27 PVD28074.1 - 5.2e-08 33.0 17.9 2.2e-06 27.8 7.4 7.8 9 0 0 9 9 9 2 EGF-like domain VWC PF00093.18 PVD28074.1 - 3.5e-05 24.0 9.8 3.5e-05 24.0 9.8 8.0 7 1 2 9 9 9 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 PVD28074.1 - 9.9 6.0 42.2 0.26 11.0 1.2 5.7 5 0 0 5 5 5 0 Pacifastin inhibitor (LCMII) Y_phosphatase PF00102.27 PVD28075.1 - 1.9e-55 188.0 0.5 2.9e-55 187.4 0.5 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yeast_MT PF11403.8 PVD28075.1 - 0.063 13.9 11.3 0.14 12.7 11.3 1.5 1 0 0 1 1 1 0 Yeast metallothionein PulG PF11773.8 PVD28076.1 - 0.084 12.7 0.2 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Ank_2 PF12796.7 PVD28077.1 - 9.3e-21 74.2 2.2 2.1e-08 34.7 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SAM_1 PF00536.30 PVD28077.1 - 6.8e-19 68.1 0.1 1.6e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_4 PF13637.6 PVD28077.1 - 8.6e-15 54.9 1.0 7.1e-06 26.5 0.0 5.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) SAM_2 PF07647.17 PVD28077.1 - 5.8e-14 51.9 0.1 7.4e-13 48.4 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 PVD28077.1 - 4e-13 49.3 2.2 1.2e-05 25.5 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD28077.1 - 7.7e-13 47.4 0.7 0.23 12.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PVD28077.1 - 5.5e-12 45.6 4.3 0.049 14.1 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat PDZ_6 PF17820.1 PVD28077.1 - 4.4e-11 42.4 1.1 1.1e-09 38.0 0.1 3.4 4 0 0 4 4 4 1 PDZ domain PDZ PF00595.24 PVD28077.1 - 5.9e-10 39.4 0.2 2.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD28077.1 - 0.022 15.1 0.0 0.098 13.0 0.0 2.2 1 0 0 1 1 1 0 PDZ domain Ras PF00071.22 PVD28078.1 - 4.8e-39 133.6 0.0 5.8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28078.1 - 1.7e-32 112.2 0.0 2.6e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28078.1 - 2.3e-10 40.2 0.0 3.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD28078.1 - 7.4e-07 28.8 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD28078.1 - 1e-05 25.2 0.0 0.00054 19.5 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD28078.1 - 6.1e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 PVD28078.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 PVD28078.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 PVD28078.1 - 0.041 13.3 0.0 0.52 9.7 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PVD28078.1 - 0.068 13.1 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gly_acyl_tr_C PF08444.10 PVD28078.1 - 0.088 13.0 0.1 3.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region AAA_16 PF13191.6 PVD28078.1 - 0.093 13.1 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PhyH PF05721.13 PVD28079.1 - 2.2e-08 34.6 0.0 1.1e-07 32.4 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 PVD28079.1 - 0.03 14.7 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Integrase_H2C2 PF17921.1 PVD28080.1 - 3.1e-14 52.8 0.1 5.3e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3551 PF12071.8 PVD28081.1 - 0.011 15.7 1.2 1.3 9.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) DUF1936 PF09151.10 PVD28082.1 - 2 8.4 15.9 4.6 7.2 0.0 5.9 7 0 0 7 7 7 0 Domain of unknown function (DUF1936) DUF3551 PF12071.8 PVD28082.1 - 3.5 7.7 28.9 3.8 7.6 0.2 7.5 8 0 0 8 8 8 0 Protein of unknown function (DUF3551) BSMAP PF12280.8 PVD28086.1 - 0.004 17.4 2.7 1.7 8.8 0.0 2.5 2 1 0 2 2 2 2 Brain specific membrane anchored protein Spo7_2_N PF15407.6 PVD28088.1 - 0.019 14.6 0.0 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 PRKCSH-like PF12999.7 PVD28088.1 - 0.052 13.4 0.2 6.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like Caenor_Her-1 PF09232.10 PVD28088.1 - 0.13 12.4 1.8 1.9 8.6 0.5 2.4 2 0 0 2 2 2 0 Caenorhabditis elegans Her-1 UPF0370 PF13980.6 PVD28088.1 - 0.19 11.8 0.1 25 5.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DUF5437 PF17505.2 PVD28088.1 - 0.59 10.2 4.6 14 5.8 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5437) p450 PF00067.22 PVD28090.1 - 7.3e-41 140.4 0.6 2.2e-23 82.7 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 TPR_1 PF00515.28 PVD28091.1 - 2.8e-42 140.9 17.4 1.6e-07 30.8 0.1 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 PVD28091.1 - 1.2e-36 121.9 18.3 4.2e-05 23.3 0.0 12.8 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 PVD28091.1 - 5.9e-32 109.8 19.9 1.2e-08 35.2 0.0 9.7 5 2 5 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 PVD28091.1 - 4.7e-27 94.3 0.0 1.6e-06 28.6 0.0 7.8 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 PVD28091.1 - 1.9e-26 90.9 21.9 0.00075 20.0 0.0 11.7 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28091.1 - 2.4e-24 85.6 2.0 0.0016 18.9 0.0 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD28091.1 - 2.7e-24 83.3 28.3 0.019 15.2 0.0 12.5 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 PVD28091.1 - 3.5e-24 83.0 12.8 0.0037 17.2 0.0 11.6 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 PVD28091.1 - 2.6e-19 68.2 0.0 0.0057 17.4 0.0 10.1 6 3 5 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD28091.1 - 2.8e-17 62.1 4.9 5.3e-05 22.8 0.0 8.0 6 1 2 8 8 8 2 TPR repeat ANAPC3 PF12895.7 PVD28091.1 - 2e-15 56.8 16.1 3.6e-05 23.9 2.0 6.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PVD28091.1 - 9.8e-11 41.7 0.0 0.0063 16.6 0.0 6.1 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD28091.1 - 1.3e-09 37.7 10.5 9.7 6.8 0.0 9.1 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2225 PF09986.9 PVD28091.1 - 2.2e-08 34.1 10.7 2.9e-05 23.9 0.4 4.3 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 PVD28091.1 - 9.7e-08 31.7 12.8 0.076 12.9 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 PVD28091.1 - 2e-06 27.7 13.2 0.00053 19.7 2.0 3.5 3 1 0 3 3 2 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 PVD28091.1 - 4.9e-06 26.1 0.2 0.22 10.9 0.0 4.3 2 1 1 4 4 4 1 MalT-like TPR region RPN7 PF10602.9 PVD28091.1 - 2.1e-05 24.3 8.9 0.0072 16.0 0.0 5.5 3 2 3 6 6 6 1 26S proteasome subunit RPN7 DUF3808 PF10300.9 PVD28091.1 - 0.00028 19.8 0.4 0.00028 19.8 0.4 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF3808) Coatomer_E PF04733.14 PVD28091.1 - 0.0007 19.1 3.2 0.08 12.3 0.0 4.0 4 1 0 4 4 4 1 Coatomer epsilon subunit TPR_4 PF07721.14 PVD28091.1 - 0.0016 18.9 0.0 10 7.1 0.0 4.7 5 0 0 5 5 2 0 Tetratricopeptide repeat Sel1 PF08238.12 PVD28091.1 - 0.0034 18.0 7.8 13 6.6 0.3 5.8 5 0 0 5 5 5 0 Sel1 repeat TPR_15 PF13429.6 PVD28091.1 - 0.0059 15.9 18.5 0.1 11.8 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 PVD28091.1 - 0.0069 16.8 2.3 4.4 7.7 0.1 4.9 3 1 2 5 5 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 PVD28091.1 - 0.0079 16.5 6.1 3.6 8.0 0.0 5.7 4 2 2 6 6 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PVD28091.1 - 0.034 13.8 0.0 9.8 5.8 0.0 3.3 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 PVD28091.1 - 0.052 13.8 4.6 17 5.9 0.0 6.0 7 0 0 7 7 5 0 PPR repeat DUF4810 PF16068.5 PVD28091.1 - 0.064 13.8 5.2 9.8 6.8 0.0 5.7 6 2 1 7 7 5 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.6 PVD28091.1 - 0.96 9.6 11.4 51 4.0 0.1 6.0 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 PVD28091.1 - 2.3 8.3 19.2 24 5.0 0.2 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat WDCP PF15390.6 PVD28092.1 - 6.6e-58 196.7 20.4 2.6e-29 102.2 3.5 3.0 1 1 1 2 2 2 2 WD repeat and coiled-coil-containing protein family Macro PF01661.21 PVD28092.1 - 5.4e-17 61.9 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Macro domain CRAL_TRIO_2 PF13716.6 PVD28092.1 - 6.9e-14 52.2 0.2 1.6e-13 51.0 0.2 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 PVD28092.1 - 0.0054 16.5 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain TRAF_BIRC3_bd PF16673.5 PVD28092.1 - 0.084 12.7 0.4 0.17 11.7 0.4 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain C1_1 PF00130.22 PVD28093.1 - 0.039 13.9 4.1 0.13 12.2 4.1 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.8 PVD28093.1 - 0.039 14.1 2.4 0.16 12.2 2.4 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 PVD28093.1 - 0.059 13.3 4.0 0.31 11.0 4.0 2.3 1 0 0 1 1 1 0 PHD-finger HEAT PF02985.22 PVD28093.1 - 0.25 11.7 5.7 8.2 7.0 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat Zf_RING PF16744.5 PVD28093.1 - 0.43 10.7 5.7 2.4 8.3 5.7 2.3 1 0 0 1 1 1 0 KIAA1045 RING finger Syja_N PF02383.18 PVD28095.1 - 2.4e-76 257.1 0.0 5.1e-76 256.0 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain SASA PF03629.18 PVD28096.1 - 1.2e-13 51.3 0.0 3.2e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD28097.1 - 6e-14 52.2 0.0 1.8e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase GST_N_2 PF13409.6 PVD28098.1 - 2.3e-24 85.4 0.1 1.9e-22 79.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD28098.1 - 4.8e-14 52.1 0.0 1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD28098.1 - 1.2e-06 28.6 0.1 2.2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD28098.1 - 1.2e-05 25.4 0.1 2.8e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PVD28098.1 - 8.5e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD28098.1 - 0.0021 18.4 0.2 0.034 14.5 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.22 PVD28100.1 - 9.6e-48 159.9 1.0 1.3e-17 63.3 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 PVD28100.1 - 5.5e-25 87.1 0.0 1.3e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 PVD28100.1 - 2.8e-07 30.6 0.1 0.88 9.7 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 PVD28100.1 - 1.9e-05 24.2 0.0 7.7e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD28100.1 - 3e-05 23.8 0.1 0.34 10.8 0.1 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF1866 PF08952.11 PVD28100.1 - 0.0016 18.3 0.0 1.1 9.1 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1866) RRM_3 PF08777.11 PVD28100.1 - 0.026 14.6 2.0 0.042 13.9 0.5 2.1 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 PVD28100.1 - 0.13 12.3 0.1 17 5.5 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 PVD28100.1 - 0.13 11.9 0.5 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated DUF5115 PF17142.4 PVD28100.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) RRM_1 PF00076.22 PVD28101.1 - 1.7e-23 82.2 0.0 2e-13 49.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 PVD28101.1 - 4.1e-10 39.5 0.4 8.7e-10 38.4 0.4 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 PVD28101.1 - 0.00092 19.3 0.1 0.56 10.3 0.0 3.5 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 PVD28101.1 - 0.001 19.1 0.5 0.013 15.5 0.1 2.6 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 PVD28101.1 - 0.0011 19.0 0.5 1.7 8.7 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 PVD28101.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) ADH_zinc_N_2 PF13602.6 PVD28102.1 - 3.1e-05 25.0 0.0 0.00012 23.2 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD28102.1 - 8.8e-05 22.3 0.2 0.00017 21.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PVD28102.1 - 0.0003 20.8 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PH_13 PF16652.5 PVD28103.1 - 8.6e-54 181.6 0.0 8.6e-54 181.6 0.0 2.7 3 1 0 3 3 1 1 Pleckstrin homology domain SH3_9 PF14604.6 PVD28103.1 - 1.9e-53 178.1 6.1 3.2e-17 62.1 0.1 6.2 6 0 0 6 6 6 5 Variant SH3 domain SH3_1 PF00018.28 PVD28103.1 - 7e-53 176.0 8.7 6.2e-16 57.7 0.1 5.4 5 0 0 5 5 5 5 SH3 domain RhoGEF PF00621.20 PVD28103.1 - 2.3e-43 148.6 0.7 2.3e-43 148.6 0.7 2.2 2 0 0 2 2 1 1 RhoGEF domain SH3_2 PF07653.17 PVD28103.1 - 1.4e-42 143.1 0.2 3.1e-11 42.8 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain C2 PF00168.30 PVD28103.1 - 8.4e-19 67.8 0.0 1.7e-17 63.6 0.0 2.8 3 0 0 3 3 3 1 C2 domain EF-hand_4 PF12763.7 PVD28103.1 - 1.2e-15 57.3 0.0 2.4e-07 30.7 0.0 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD28103.1 - 1.4e-06 27.4 0.5 0.024 14.2 0.1 2.9 2 0 0 2 2 2 2 EF hand PH PF00169.29 PVD28103.1 - 0.00015 22.3 0.0 0.00047 20.6 0.0 1.9 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 PVD28103.1 - 0.0023 17.7 0.7 0.7 10.0 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 PVD28103.1 - 0.0031 17.3 1.0 0.17 11.7 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD28103.1 - 0.0038 16.6 0.1 0.71 9.5 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD28103.1 - 0.043 14.3 0.1 5.8 7.4 0.1 3.4 3 0 0 3 3 2 0 EF-hand domain pair Dockerin_1 PF00404.18 PVD28103.1 - 0.16 12.2 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain GPHH PF16905.5 PVD28106.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Exo_endo_phos PF03372.23 PVD28107.1 - 3e-19 69.5 0.0 4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD28107.1 - 0.024 14.5 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase T2SSM PF04612.12 PVD28107.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1213 PF06740.12 PVD28107.1 - 0.87 10.2 3.8 2.1 9.0 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) Ank_2 PF12796.7 PVD28108.1 - 4.7e-22 78.4 0.9 1e-09 38.8 0.4 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD28108.1 - 2.4e-20 70.4 10.1 0.0021 18.4 0.1 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 PVD28108.1 - 8.4e-19 67.7 4.7 0.00012 22.5 0.1 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD28108.1 - 1.5e-13 50.7 5.9 0.0011 19.2 0.2 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD28108.1 - 1.9e-11 43.9 16.4 0.013 15.9 0.6 6.8 7 0 0 7 7 7 3 Ankyrin repeat SOCS_box PF07525.16 PVD28108.1 - 0.098 13.0 5.6 0.093 13.1 2.0 2.3 2 0 0 2 2 2 0 SOCS box CHD5 PF04420.14 PVD28109.1 - 1.3e-12 47.9 0.2 1.6e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 CHD5-like protein Lebercilin PF15619.6 PVD28110.1 - 4.6e-51 173.2 49.4 4.6e-51 173.2 49.4 3.6 3 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease SH3BGR PF04908.15 PVD28111.1 - 5.7e-22 77.7 0.3 5.7e-22 77.7 0.3 3.8 3 2 2 5 5 5 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 PVD28111.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.9 3 1 1 4 4 4 0 Glutaredoxin UPRTase PF14681.6 PVD28113.1 - 7.1e-53 179.1 0.0 8.9e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 PVD28113.1 - 0.0043 16.6 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain APG6_N PF17675.1 PVD28114.1 - 0.0072 16.9 22.0 0.0072 16.9 22.0 9.9 2 2 6 9 9 9 3 Apg6 coiled-coil region Filament PF00038.21 PVD28115.1 - 0.0066 16.1 8.9 0.0066 16.1 8.9 9.7 1 1 8 10 10 10 3 Intermediate filament protein ADIP PF11559.8 PVD28115.1 - 0.0093 16.1 18.1 0.0093 16.1 18.1 11.9 4 3 10 14 14 14 3 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 PVD28115.1 - 0.015 15.1 2.0 0.015 15.1 2.0 10.2 2 2 9 11 11 11 0 Protein of unknown function (DUF724) Spc7 PF08317.11 PVD28115.1 - 0.16 10.8 167.3 0.019 13.9 15.2 8.3 1 1 7 9 9 9 0 Spc7 kinetochore protein DUF2939 PF11159.8 PVD28115.1 - 0.43 11.0 2.3 7.6 7.0 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Glu-tRNAGln PF02686.15 PVD28115.1 - 1.4 9.2 6.1 13 6.2 0.9 4.1 2 1 1 3 3 3 0 Glu-tRNAGln amidotransferase C subunit ATG16 PF08614.11 PVD28116.1 - 0.00039 20.7 91.4 0.018 15.2 12.1 6.3 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 PVD28116.1 - 0.025 14.9 3.9 0.025 14.9 3.9 10.0 5 3 5 11 11 11 0 Csm1 N-terminal domain KASH_CCD PF14662.6 PVD28116.1 - 0.028 14.2 95.4 0.11 12.3 14.9 5.4 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH Ribosomal_L31 PF01197.18 PVD28116.1 - 0.035 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L31 Filament PF00038.21 PVD28116.1 - 2.1 7.9 75.9 0.0066 16.1 35.5 3.8 1 1 2 3 3 3 0 Intermediate filament protein CALCOCO1 PF07888.11 PVD28116.1 - 2.9 6.7 82.2 0.037 12.9 18.2 4.2 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 PVD28116.1 - 8.5 5.2 91.8 0.13 11.2 6.8 5.0 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF948 PF06103.11 PVD28117.1 - 0.0054 17.0 48.1 0.6 10.4 2.8 8.2 5 2 1 7 7 7 6 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 PVD28117.1 - 0.0076 16.3 14.1 0.0076 16.3 14.1 9.4 2 2 5 9 9 9 2 Designed helical repeat protein 10 domain Fez1 PF06818.15 PVD28117.1 - 0.066 13.7 115.5 0.027 14.9 20.0 6.7 1 1 5 6 6 6 0 Fez1 PLAC9 PF15205.6 PVD28117.1 - 0.77 10.2 4.7 17 5.9 0.2 3.6 3 0 0 3 3 3 0 Placenta-specific protein 9 Coat_F PF07875.12 PVD28118.1 - 0.2 11.9 4.7 0.82 9.9 1.1 4.3 2 0 0 2 2 2 0 Coat F domain T2SS_PulS_OutS PF09691.10 PVD28118.1 - 1.9 8.7 7.4 0.92 9.7 0.4 4.0 3 0 0 3 3 3 0 Type II secretion system pilotin lipoprotein (PulS_OutS) DUF713 PF05218.14 PVD28119.1 - 0.0098 15.6 5.3 0.019 14.7 4.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF713) FlgT_C PF16538.5 PVD28119.1 - 0.048 14.2 1.0 0.11 13.0 1.0 1.6 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain KH_9 PF17904.1 PVD28119.1 - 0.048 14.0 3.2 4.5 7.7 0.1 3.1 2 1 1 3 3 3 0 FMRP KH0 domain GED PF02212.18 PVD28119.1 - 4.4 7.5 10.3 2.1 8.5 0.3 3.4 2 1 2 4 4 4 0 Dynamin GTPase effector domain TMF_TATA_bd PF12325.8 PVD28120.1 - 0.00023 21.3 10.0 0.00023 21.3 10.0 10.0 4 2 6 10 10 10 5 TATA element modulatory factor 1 TATA binding Cons_hypoth95 PF03602.15 PVD28120.1 - 0.01 15.5 0.4 0.01 15.5 0.4 2.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 ATG16 PF08614.11 PVD28120.1 - 0.45 10.7 138.0 0.026 14.8 28.7 8.2 4 2 2 7 7 7 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 PVD28120.1 - 9.9 4.9 124.6 0.14 11.0 17.1 6.9 3 2 4 7 7 7 0 Spc7 kinetochore protein Spc7 PF08317.11 PVD28121.1 - 0.00051 19.0 16.2 0.00051 19.0 16.2 23.0 4 3 18 24 24 24 20 Spc7 kinetochore protein ACC_central PF08326.12 PVD28122.1 - 1.7e-253 843.2 7.3 2.1e-253 842.9 7.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 PVD28122.1 - 1.1e-171 571.8 0.0 1.7e-171 571.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain Glyco_transf_7N PF13733.6 PVD28122.1 - 1.9e-52 176.5 0.1 4.2e-52 175.3 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 CPSase_L_D2 PF02786.17 PVD28122.1 - 2.7e-51 174.1 0.0 6.5e-51 172.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PVD28122.1 - 9e-33 113.1 0.1 2.3e-32 111.8 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Glyco_transf_7C PF02709.14 PVD28122.1 - 9.8e-26 89.2 0.3 2.5e-25 87.9 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Biotin_carb_C PF02785.19 PVD28122.1 - 8.4e-21 74.1 0.0 5.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PVD28122.1 - 4.6e-11 42.4 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PVD28122.1 - 0.0025 17.4 0.0 0.006 16.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SEN1_N PF12726.7 PVD28122.1 - 0.0042 15.4 0.2 0.0074 14.6 0.2 1.3 1 0 0 1 1 1 1 SEN1 N terminal ATP-grasp_3 PF02655.14 PVD28122.1 - 0.0064 16.5 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Fz PF01392.22 PVD28125.1 - 7.8e-31 107.0 4.9 1.1e-30 106.5 4.9 1.2 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 PVD28126.1 - 4.6e-103 344.7 22.7 7e-86 288.2 14.7 2.0 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 PVD28126.1 - 0.00013 21.2 5.3 0.00013 21.2 5.3 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GRP PF07172.11 PVD28126.1 - 0.13 13.0 22.8 0.25 12.1 22.8 1.5 1 0 0 1 1 1 0 Glycine rich protein family HemY_N PF07219.13 PVD28126.1 - 8.3 6.7 6.8 18 5.6 0.1 2.9 3 0 0 3 3 3 0 HemY protein N-terminus GAS PF13851.6 PVD28129.1 - 0.0045 16.4 2.6 0.0066 15.8 2.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 PVD28129.1 - 0.018 15.7 2.1 0.038 14.7 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) WD40 PF00400.32 PVD28130.1 - 5.1e-30 103.1 8.6 2.2e-09 37.8 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28130.1 - 1.9e-09 37.7 0.0 0.11 12.8 0.0 4.7 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PVD28130.1 - 2.9e-05 23.8 0.1 0.00017 21.3 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 PVD28130.1 - 3.5e-05 22.9 0.6 0.15 11.0 0.0 3.2 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 PVD28130.1 - 0.0055 16.6 0.0 0.44 10.6 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 PVD28130.1 - 0.046 14.2 1.2 1.6 9.3 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain PD40 PF07676.12 PVD28130.1 - 0.1 12.6 0.1 40 4.3 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Reprolysin_2 PF13574.6 PVD28131.1 - 1.2e-30 106.8 1.5 2.3e-30 106.0 1.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD28131.1 - 1.2e-26 94.1 1.7 4.2e-26 92.3 1.3 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD28131.1 - 4e-15 56.4 0.9 9e-15 55.3 0.4 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 PVD28131.1 - 3.5e-13 50.0 0.2 6.7e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 PVD28131.1 - 5e-12 45.9 1.4 1.2e-11 44.6 1.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD28131.1 - 8.7e-08 32.8 24.9 8.7e-08 32.8 24.9 3.4 3 0 0 3 3 3 1 Disintegrin Peptidase_M66 PF10462.9 PVD28131.1 - 0.0066 15.4 0.1 0.014 14.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase M66 UPF0370 PF13980.6 PVD28131.1 - 0.029 14.4 3.7 0.17 11.9 4.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) NDUF_B8 PF05821.11 PVD28132.1 - 1.8e-49 168.0 5.7 2.2e-49 167.7 5.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF3298 PF11738.8 PVD28132.1 - 0.23 12.5 1.7 0.41 11.7 0.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) DUF4139 PF13598.6 PVD28133.1 - 6.3e-53 179.6 0.0 8.6e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 PVD28133.1 - 1.3e-24 86.5 2.5 1.3e-24 86.5 2.5 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) 7tm_1 PF00001.21 PVD28134.1 - 0.0011 18.4 9.8 0.03 13.7 9.8 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD28134.1 - 0.0024 17.7 0.2 0.0024 17.7 0.2 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD28134.1 - 0.0027 17.1 0.2 0.0027 17.1 0.2 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD28134.1 - 0.0074 15.9 10.1 0.028 14.0 3.1 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 PVD28134.1 - 0.03 13.8 11.2 0.089 12.3 11.2 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc UL45 PF05473.12 PVD28134.1 - 8.7 5.9 7.9 63 3.1 7.9 2.2 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Arf PF00025.21 PVD28135.1 - 1.5e-33 115.7 0.0 3.5e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PVD28135.1 - 4.7e-10 39.2 0.1 1.8e-06 27.4 0.0 3.1 3 0 0 3 3 3 2 G-protein alpha subunit Ras PF00071.22 PVD28135.1 - 3.1e-05 23.6 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28135.1 - 3.9e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AhpC-TSA PF00578.21 PVD28136.1 - 9.3e-36 122.5 0.0 1.3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 PVD28136.1 - 5.6e-13 48.5 0.3 1.1e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 PVD28136.1 - 7.4e-13 48.4 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin LPMO_10 PF03067.15 PVD28138.1 - 5.7e-34 118.5 0.7 7.6e-34 118.1 0.7 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Pepdidase_M14_N PF18027.1 PVD28138.1 - 0.038 14.4 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain zf-C3HC4_3 PF13920.6 PVD28139.1 - 3.2e-13 49.3 16.2 4.8e-13 48.8 16.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28139.1 - 0.0001 22.1 15.3 0.00018 21.3 15.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD28139.1 - 0.043 14.2 17.9 0.071 13.5 17.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PVD28139.1 - 0.12 12.3 16.5 0.21 11.6 16.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Fe-ADH_2 PF13685.6 PVD28140.1 - 0.22 11.2 0.8 0.26 10.9 0.8 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF2671 PF10877.8 PVD28142.1 - 0.23 11.3 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) BIR PF00653.21 PVD28143.1 - 3e-52 175.2 19.7 1.2e-20 74.0 3.9 3.9 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD28143.1 - 4.4e-12 45.7 15.4 4.4e-12 45.7 15.4 2.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28143.1 - 0.0012 18.6 15.3 0.0012 18.6 15.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Bombinin PF05298.11 PVD28143.1 - 0.063 13.0 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Bombinin NuA4 PF09340.10 PVD28144.1 - 7.6e-27 93.0 0.7 7.6e-27 93.0 0.7 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 QWRF PF04484.12 PVD28144.1 - 0.035 13.8 2.0 0.04 13.7 2.0 1.1 1 0 0 1 1 1 0 QWRF family PX PF00787.24 PVD28145.1 - 3.1e-21 75.5 0.0 3.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 PX domain AFG1_ATPase PF03969.16 PVD28146.1 - 2.2e-108 362.4 0.2 5.6e-104 347.9 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 PVD28146.1 - 2.5e-05 24.2 1.5 0.69 9.7 0.0 3.7 4 0 0 4 4 4 2 Bacterial dnaA protein AAA_16 PF13191.6 PVD28146.1 - 0.00028 21.3 0.5 0.076 13.4 0.6 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 PVD28146.1 - 0.0015 19.0 0.0 0.0051 17.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PVD28146.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PVD28146.1 - 0.025 14.9 0.0 0.077 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PVD28146.1 - 0.026 14.6 0.0 0.096 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD28146.1 - 0.047 13.6 0.1 0.16 11.9 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Retrotrans_gag PF03732.17 PVD28147.1 - 0.00023 21.4 0.0 0.00057 20.1 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Ras PF00071.22 PVD28148.1 - 8.4e-15 54.7 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 PVD28148.1 - 0.0043 16.6 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain C8 PF08742.11 PVD28149.1 - 0.055 13.9 1.2 0.13 12.7 1.2 1.7 1 0 0 1 1 1 0 C8 domain MutS_V PF00488.21 PVD28152.1 - 1.9e-83 279.1 0.2 4.8e-83 277.8 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 PVD28152.1 - 7.9e-36 124.1 2.3 2.2e-35 122.6 0.9 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 PVD28152.1 - 7.6e-21 74.3 3.5 2e-20 72.9 3.5 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PVD28152.1 - 1.8e-16 60.7 3.4 4.8e-16 59.3 0.0 3.3 4 0 0 4 4 4 1 MutS domain II MutS_I PF01624.20 PVD28152.1 - 5.6e-11 42.7 0.0 1.5e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 PVD28152.1 - 0.00075 19.1 0.5 0.0029 17.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain zf-C4H2 PF10146.9 PVD28153.1 - 7.3e-76 255.2 15.9 8.5e-76 255.0 15.9 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein ETC_C1_NDUFA5 PF04716.14 PVD28153.1 - 0.0053 16.5 1.0 0.015 15.1 1.0 1.7 1 0 0 1 1 1 1 ETC complex I subunit conserved region DZR PF12773.7 PVD28153.1 - 0.0079 16.2 0.7 0.014 15.4 0.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon Occludin_ELL PF07303.13 PVD28153.1 - 0.017 15.8 2.7 0.017 15.8 2.7 1.9 2 0 0 2 2 2 0 Occludin homology domain zf-C3HC4_3 PF13920.6 PVD28153.1 - 0.059 13.2 4.2 0.12 12.3 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PVD28153.1 - 0.09 12.6 2.7 0.24 11.2 2.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PVD28153.1 - 0.29 10.8 4.4 0.17 11.5 2.2 1.7 2 0 0 2 2 2 0 P-11 zinc finger DUF4404 PF14357.6 PVD28153.1 - 0.41 11.3 11.4 0.4 11.3 7.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) FapA PF03961.13 PVD28153.1 - 1.2 7.6 5.4 1.8 7.1 5.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 PVD28153.1 - 1.7 9.3 10.8 0.27 11.9 0.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CREPT PF16566.5 PVD28153.1 - 3.6 7.7 14.3 4.2 7.5 9.9 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PPP1R32 PF15691.5 PVD28154.1 - 1.1e-152 509.0 9.3 1.2e-152 508.8 9.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 Brix PF04427.18 PVD28155.1 - 1.1e-36 126.8 0.3 1.1e-36 126.8 0.3 1.7 2 0 0 2 2 2 1 Brix domain Aa_trans PF01490.18 PVD28156.1 - 7.9e-73 245.5 25.9 8.9e-73 245.3 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 PVD28157.1 - 5e-61 206.6 21.5 6.2e-61 206.3 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_3_7 PF05449.11 PVD28157.1 - 0.84 9.7 7.7 5.8 7.0 0.2 3.3 3 0 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 GCV_T PF01571.21 PVD28158.1 - 0.0066 15.8 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain zf-B_box PF00643.24 PVD28159.1 - 1.4e-08 34.8 4.1 1.4e-08 34.8 4.1 5.4 8 1 0 8 8 8 2 B-box zinc finger NHL PF01436.21 PVD28159.1 - 6.7e-07 29.0 3.8 0.67 10.1 0.1 3.8 3 0 0 3 3 3 3 NHL repeat zf-RING_UBOX PF13445.6 PVD28159.1 - 5.2e-05 23.2 1.8 5.2e-05 23.2 1.8 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD28159.1 - 7.3e-05 22.6 3.9 7.3e-05 22.6 3.9 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28159.1 - 0.00057 20.2 4.2 0.00057 20.2 4.2 4.8 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD28159.1 - 0.00092 19.0 2.0 0.00092 19.0 2.0 4.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD28159.1 - 0.0014 18.5 3.6 0.0014 18.5 3.6 4.8 4 2 0 4 4 4 1 zinc-RING finger domain zf-RING_6 PF14835.6 PVD28159.1 - 0.0047 16.8 1.3 0.0047 16.8 1.3 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zinc_ribbon_4 PF13717.6 PVD28159.1 - 6.2 6.8 11.3 25 4.9 0.1 4.7 4 0 0 4 4 4 0 zinc-ribbon domain Arm PF00514.23 PVD28160.1 - 3.5e-83 271.4 16.0 3e-13 49.3 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 PVD28160.1 - 5.6e-26 90.8 1.0 2e-25 89.1 1.0 2.0 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 PVD28160.1 - 4.7e-19 67.7 0.1 4e-18 64.7 0.3 2.4 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_EZ PF13513.6 PVD28160.1 - 4e-18 65.5 2.1 1.8e-06 28.3 0.1 5.5 5 1 0 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 PVD28160.1 - 6e-18 65.0 2.6 7.3e-06 26.3 0.0 6.2 1 1 6 7 7 7 7 HEAT repeats HEAT PF02985.22 PVD28160.1 - 8.1e-13 47.4 1.8 0.0016 18.5 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat V-ATPase_H_C PF11698.8 PVD28160.1 - 1.5e-05 25.1 0.0 0.17 12.0 0.1 3.4 3 0 0 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.20 PVD28160.1 - 9.2e-05 21.2 0.0 0.0027 16.3 0.0 2.4 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 PVD28160.1 - 0.00073 19.6 0.1 3 7.9 0.1 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 PVD28160.1 - 0.0012 19.0 1.4 5.3 7.4 0.0 5.0 5 1 2 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 UxaC PF02614.14 PVD28160.1 - 0.0045 15.9 0.0 3 6.6 0.0 2.7 3 0 0 3 3 3 2 Glucuronate isomerase ParcG PF10274.9 PVD28160.1 - 0.077 13.1 0.2 9.8 6.3 0.1 3.1 2 1 0 3 3 3 0 Parkin co-regulated protein Peptidase_C78 PF07910.13 PVD28160.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C78 FOP_dimer PF09398.10 PVD28161.1 - 3e-24 85.1 0.3 8.8e-24 83.6 0.3 1.8 1 0 0 1 1 1 1 FOP N terminal dimerisation domain EF-hand_7 PF13499.6 PVD28161.1 - 7.5e-11 42.3 5.2 7.5e-11 42.3 5.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD28161.1 - 5.1e-09 35.4 6.9 1.9e-05 24.2 1.6 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PVD28161.1 - 1.9e-07 30.1 7.0 4.1e-05 22.8 1.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 PVD28161.1 - 6.7e-05 22.2 10.7 0.00031 20.1 1.0 3.4 3 0 0 3 3 3 2 EF hand LisH_2 PF16045.5 PVD28161.1 - 0.00031 19.7 0.0 0.00071 18.5 0.0 1.7 1 0 0 1 1 1 1 LisH EF-hand_8 PF13833.6 PVD28161.1 - 0.0043 16.9 4.7 0.69 9.8 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain pair PNISR PF15996.5 PVD28162.1 - 1.1e-46 159.7 19.9 1.1e-46 159.7 19.9 6.5 3 1 2 6 6 6 1 Arginine/serine-rich protein PNISR PRIMA1 PF16101.5 PVD28162.1 - 0.87 9.6 5.3 5.1 7.2 5.3 2.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_11 PF08241.12 PVD28163.1 - 7.9e-21 74.5 0.0 1.5e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD28163.1 - 7.5e-16 58.6 0.1 1.4e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD28163.1 - 3.4e-15 56.2 0.0 4.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD28163.1 - 4e-14 52.8 0.0 6.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD28163.1 - 2.4e-12 47.5 0.0 4.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD28163.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PVD28163.1 - 3e-07 30.0 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 PVD28163.1 - 8e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 PVD28163.1 - 0.00015 21.2 0.3 0.00024 20.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 PVD28163.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GidB PF02527.15 PVD28163.1 - 0.0027 17.0 0.7 0.025 13.9 0.7 2.0 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G NodS PF05401.11 PVD28163.1 - 0.0037 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 PVD28163.1 - 0.0049 16.7 0.1 0.0071 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 PVD28163.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 PVD28163.1 - 0.0077 16.2 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 PVD28163.1 - 0.059 13.5 0.1 0.092 12.9 0.1 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1704 PF08014.11 PVD28164.1 - 0.00041 19.5 0.1 0.13 11.2 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1704) N6-adenineMlase PF10237.9 PVD28165.1 - 6.3e-55 185.4 0.0 8.2e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 PVD28165.1 - 0.0055 16.4 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 ABC_membrane PF00664.23 PVD28166.1 - 4.8e-38 131.4 8.3 6.5e-38 130.9 8.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD28166.1 - 1.9e-33 115.9 0.0 3.9e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD28166.1 - 0.00027 20.5 1.8 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD28166.1 - 0.0056 17.1 0.1 0.018 15.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD28166.1 - 0.0082 16.4 0.1 0.054 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PVD28166.1 - 0.014 15.1 0.4 0.043 13.6 0.4 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 PVD28166.1 - 0.017 14.3 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 PVD28166.1 - 0.02 15.0 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 PVD28166.1 - 0.027 14.2 0.1 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 PVD28166.1 - 0.049 12.7 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 PVD28166.1 - 0.064 13.0 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD28166.1 - 0.085 12.6 0.0 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD28166.1 - 0.092 12.2 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region HRI1 PF16815.5 PVD28166.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein HRI1 AAA_28 PF13521.6 PVD28166.1 - 0.098 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 PVD28166.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 PVD28166.1 - 0.11 11.8 0.3 0.97 8.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 PVD28166.1 - 0.15 12.2 0.1 1 9.5 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase SASA PF03629.18 PVD28167.1 - 3.3e-16 59.6 0.2 6.5e-16 58.6 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase PDZ_6 PF17820.1 PVD28169.1 - 3.1e-13 49.3 0.1 4.9e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD28169.1 - 5.9e-10 39.4 0.0 8.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD28169.1 - 9.9e-08 32.2 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 PVD28169.1 - 0.0057 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain RhoGEF PF00621.20 PVD28170.1 - 4.4e-12 46.6 0.3 9.3e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain Homeodomain PF00046.29 PVD28171.1 - 0.0078 16.0 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Inj_translocase PF16928.5 PVD28171.1 - 0.015 14.8 0.4 0.02 14.3 0.4 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome UBA PF00627.31 PVD28176.1 - 2.1e-05 24.3 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_S21 PF00716.17 PVD28177.1 - 0.4 10.3 6.2 0.49 10.0 6.2 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) PA-IL PF07828.12 PVD28178.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 PA-IL-like protein SASA PF03629.18 PVD28180.1 - 1e-15 58.0 0.1 1.9e-15 57.1 0.1 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF728 PF05304.12 PVD28180.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF728) SASA PF03629.18 PVD28181.1 - 2e-13 50.5 0.1 8.7e-13 48.4 0.1 2.0 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase PHY PF00360.20 PVD28181.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Phytochrome region SASA PF03629.18 PVD28182.1 - 5.9e-14 52.3 0.0 1.5e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD28183.1 - 8.2e-15 55.1 0.0 1.6e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase WAP PF00095.21 PVD28184.1 - 0.0031 17.8 6.6 0.0082 16.5 6.6 1.7 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' 7TM_GPCR_Srx PF10328.9 PVD28185.1 - 0.0043 16.7 7.6 0.0068 16.1 7.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx WH1 PF00568.23 PVD28187.1 - 0.031 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Asp_Glu_race_2 PF14669.6 PVD28188.1 - 0.045 13.4 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative aspartate racemase IRS PF02174.17 PVD28189.1 - 1.2e-22 79.7 0.0 2e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) FAD_binding_7 PF03441.14 PVD28190.1 - 5.3e-78 261.1 1.6 7.6e-78 260.6 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PVD28190.1 - 1.5e-45 155.1 0.0 4e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Suf PF05843.14 PVD28191.1 - 1.1e-49 170.1 20.3 3.7e-37 128.9 1.2 6.5 4 2 2 6 6 6 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 PVD28191.1 - 0.0079 16.9 4.8 8.9 7.4 0.0 6.2 4 2 3 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 PVD28191.1 - 0.0088 15.2 9.2 0.81 8.7 0.2 4.5 2 1 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 PVD28191.1 - 1.1 10.0 5.0 2.4 9.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 PVD28191.1 - 3.8 7.5 7.2 10 6.2 0.1 4.0 4 1 0 4 4 4 0 HAT (Half-A-TPR) repeat TFIID-18kDa PF02269.16 PVD28192.1 - 5.1e-35 119.4 0.4 1.2e-34 118.2 0.4 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DnaJ_C PF01556.18 PVD28192.1 - 2.3e-28 99.2 0.2 2.4e-27 95.9 0.1 2.1 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 PVD28192.1 - 2.1e-07 30.9 2.2 3.5e-07 30.2 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain SF3a60_bindingd PF12108.8 PVD28192.1 - 0.015 15.2 0.4 0.041 13.8 0.4 1.8 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain LMSTEN PF07988.12 PVD28192.1 - 0.095 12.2 0.3 0.095 12.2 0.3 1.8 2 0 0 2 2 2 0 LMSTEN motif ASH PF15780.5 PVD28193.1 - 3.4e-21 75.3 5.5 0.0028 17.8 0.0 7.2 7 0 0 7 7 7 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PVD28193.1 - 1.4e-15 57.3 2.5 9.3e-09 35.4 0.1 4.8 5 0 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 PVD28193.1 - 4.5e-08 33.2 4.5 0.0057 16.9 0.1 4.9 5 0 0 5 5 5 2 Transmembrane protein 131-like DUF1573 PF07610.11 PVD28193.1 - 8.2e-08 32.2 1.0 0.4 10.7 0.1 5.7 5 0 0 5 5 5 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 PVD28193.1 - 5.4e-07 29.4 4.6 0.13 12.2 0.1 6.2 7 0 0 7 7 7 2 MSP (Major sperm protein) domain DUF538 PF04398.12 PVD28193.1 - 0.13 12.7 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF538 Cadherin PF00028.17 PVD28193.1 - 0.15 12.5 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Cadherin domain SRP40_C PF05022.12 PVD28194.1 - 4.1e-29 101.2 3.1 1.4e-28 99.5 3.1 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain BAF250_C PF12031.8 PVD28195.1 - 9.5e-100 333.1 2.1 1.4e-99 332.5 2.1 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 PVD28195.1 - 4.4e-17 62.5 0.0 1.2e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain UvrD_C_2 PF13538.6 PVD28196.1 - 2.2e-07 30.6 2.4 1e-06 28.4 1.7 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PVD28196.1 - 0.0049 16.6 0.4 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 PVD28197.1 - 0.0027 17.4 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD28197.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 PVD28198.1 - 4.3e-77 259.5 30.7 1.1e-43 149.9 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD28198.1 - 1.4e-55 187.6 0.1 5.1e-32 111.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD28198.1 - 3.8e-10 39.6 1.7 0.00052 19.5 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD28198.1 - 2.1e-06 27.8 0.2 0.063 13.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD28198.1 - 6.5e-05 22.6 0.9 0.2 11.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 PVD28198.1 - 0.00048 20.3 1.6 1.1 9.2 0.1 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 PVD28198.1 - 0.00051 20.0 0.4 0.58 10.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 PVD28198.1 - 0.0011 19.2 0.7 1.6 9.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD28198.1 - 0.0013 19.1 0.5 2.3 8.6 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 PVD28198.1 - 0.0087 15.6 0.1 4.7 6.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 PVD28198.1 - 0.01 15.1 1.0 0.44 9.8 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 PVD28198.1 - 0.024 14.2 0.1 8.7 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 PVD28198.1 - 0.024 13.5 0.0 0.05 12.4 0.0 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_21 PF13304.6 PVD28198.1 - 0.041 13.7 1.8 8.8 6.0 0.0 4.0 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 PVD28198.1 - 0.044 13.5 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD28198.1 - 0.058 13.6 0.4 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 PVD28198.1 - 0.064 12.4 0.6 2.7 7.1 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 PVD28198.1 - 0.089 12.5 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 PVD28198.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.6 3 0 0 3 3 2 0 Dynamin family ATP_bind_1 PF03029.17 PVD28198.1 - 0.13 12.0 0.2 4.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 PVD28198.1 - 0.19 11.6 0.1 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 PVD28198.1 - 0.68 9.6 2.5 16 5.1 0.2 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 PVD28198.1 - 1.8 9.1 8.1 28 5.1 0.3 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PVD28198.1 - 3.4 7.5 4.9 8.1 6.3 0.1 3.1 3 0 0 3 3 3 0 NACHT domain DUF2870 PF11069.8 PVD28199.1 - 2.4e-41 140.0 2.9 2.4e-41 140.0 2.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) FAM176 PF14851.6 PVD28200.1 - 8.3e-07 28.8 0.2 2.7e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 FAM176 family IncE PF17627.2 PVD28200.1 - 0.029 14.4 0.5 1.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Inclusion membrane protein E Gal_Lectin PF02140.18 PVD28203.1 - 1.5e-19 70.2 7.5 1.1e-17 64.2 0.7 3.8 4 1 0 4 4 4 2 Galactose binding lectin domain PLAC8 PF04749.17 PVD28206.1 - 4.5e-08 34.0 21.4 4.5e-08 34.0 21.4 3.7 3 1 0 3 3 3 1 PLAC8 family 3HCDH_N PF02737.18 PVD28207.1 - 5.9e-44 150.1 0.0 1.2e-43 149.1 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PVD28207.1 - 3.4e-11 43.6 0.1 6.6e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 PVD28207.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 PVD28207.1 - 5.5e-05 23.4 0.0 0.00013 22.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PVD28207.1 - 0.0004 20.9 0.0 0.001 19.6 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 PVD28207.1 - 0.0031 17.1 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 PVD28207.1 - 0.035 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 PVD28207.1 - 0.063 14.1 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 PVD28207.1 - 0.13 11.8 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Myb_Cef PF11831.8 PVD28210.1 - 1e-72 244.6 4.0 1e-72 244.6 4.0 3.3 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 PVD28210.1 - 1.1e-19 70.3 4.9 1.6e-11 44.2 1.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD28210.1 - 1.5e-18 66.7 6.0 1.1e-12 47.9 3.0 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Adeno_PIX PF03955.14 PVD28210.1 - 0.1 12.8 0.6 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Myosin_tail_1 PF01576.19 PVD28211.1 - 8.6e-35 119.9 20.0 1.1e-34 119.5 20.0 1.0 1 0 0 1 1 1 1 Myosin tail RVP PF00077.20 PVD28211.1 - 0.00049 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Med21 PF11221.8 PVD28211.1 - 0.036 14.3 4.1 0.036 14.3 4.1 2.8 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Asp_protease_2 PF13650.6 PVD28211.1 - 0.04 14.6 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Filament PF00038.21 PVD28211.1 - 0.066 12.8 14.1 0.095 12.3 14.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein gag-asp_proteas PF13975.6 PVD28211.1 - 0.067 13.8 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TMPIT PF07851.13 PVD28211.1 - 0.21 10.8 2.1 0.31 10.2 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.19 PVD28211.1 - 0.25 11.1 19.4 0.4 10.5 19.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4472 PF14739.6 PVD28211.1 - 0.55 11.0 15.2 0.074 13.8 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 PVD28211.1 - 0.86 10.1 23.9 0.63 10.6 11.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PVD28211.1 - 3.7 7.8 15.7 0.44 10.8 7.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CSD PF00313.22 PVD28214.1 - 0.00021 21.1 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Ras PF00071.22 PVD28218.1 - 5.3e-19 68.4 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28218.1 - 3.4e-16 59.6 0.0 2e-15 57.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28218.1 - 1.2e-10 41.1 0.0 2.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD28218.1 - 5.3e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD28218.1 - 0.00018 20.9 0.1 0.00058 19.3 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD28218.1 - 0.00058 19.3 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CLZ PF16526.5 PVD28218.1 - 0.015 15.6 0.7 18 5.7 0.0 3.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dynamin_N PF00350.23 PVD28218.1 - 0.022 14.8 0.2 3.4 7.7 0.1 2.9 1 1 1 2 2 2 0 Dynamin family AAA_23 PF13476.6 PVD28218.1 - 0.28 11.7 4.9 18 5.7 0.0 3.3 2 1 0 3 3 3 0 AAA domain 7tm_2 PF00002.24 PVD28219.1 - 6.8e-46 156.5 22.6 1e-45 155.9 22.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) LRR_8 PF13855.6 PVD28219.1 - 3.2e-23 81.3 2.6 8.1e-16 57.5 0.9 2.7 1 1 1 2 2 2 2 Leucine rich repeat GPS PF01825.21 PVD28219.1 - 1.6e-14 54.2 4.3 1.6e-14 54.2 4.3 2.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PVD28219.1 - 3.2e-10 40.1 5.6 8.2e-05 22.9 0.1 4.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD28219.1 - 6.2e-08 32.7 1.3 2.2e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD28219.1 - 4.8e-05 23.3 6.5 0.13 12.9 0.1 5.6 5 0 0 5 5 4 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD28219.1 - 0.0013 18.6 6.1 0.087 12.9 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 PVD28219.1 - 0.016 14.7 0.2 0.064 12.8 0.2 1.9 1 1 1 2 2 2 0 Leucine-rich repeat UPAR_LY6_2 PF16975.5 PVD28219.1 - 0.042 14.1 11.5 0.17 12.1 11.5 2.1 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF3634 PF12321.8 PVD28219.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) DUF2420 PF10336.9 PVD28219.1 - 0.1 12.6 0.3 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Vta1 PF04652.16 PVD28220.1 - 3.4e-53 179.5 3.7 4.3e-53 179.2 3.7 1.1 1 0 0 1 1 1 1 Vta1 like Amidase PF01425.21 PVD28222.1 - 8.4e-58 196.4 0.7 7.8e-57 193.2 0.7 1.9 1 1 0 1 1 1 1 Amidase OTU PF02338.19 PVD28223.1 - 3.7e-13 50.1 0.0 2.6e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease zf-A20 PF01754.16 PVD28223.1 - 0.00015 21.6 4.9 0.00015 21.6 4.9 5.3 5 0 0 5 5 5 3 A20-like zinc finger Sec2p PF06428.11 PVD28224.1 - 2.6e-10 40.1 7.5 7.6e-10 38.6 7.5 1.8 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Tmemb_cc2 PF10267.9 PVD28224.1 - 2.5e-06 26.9 0.1 2.5e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 PVD28224.1 - 0.00089 19.3 7.9 0.00089 19.3 7.9 1.7 2 0 0 2 2 2 1 SPX domain PEP-utilisers_N PF05524.13 PVD28224.1 - 0.17 12.1 4.8 0.35 11.1 4.8 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PA26 PF04636.13 PVD28225.1 - 1.3e-160 535.2 11.5 1.2e-99 334.3 4.4 2.0 1 1 1 2 2 2 2 PA26 p53-induced protein (sestrin) CMD PF02627.20 PVD28225.1 - 2.2e-05 24.4 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CENP-B_N PF04218.13 PVD28225.1 - 0.16 11.7 0.2 0.34 10.6 0.2 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain RhoGEF PF00621.20 PVD28226.1 - 1.7e-31 109.9 0.5 3.7e-31 108.8 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF4347 PF14252.6 PVD28226.1 - 2.6e-07 30.6 0.0 1.7e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4347) F-box PF00646.33 PVD28226.1 - 3.7e-07 29.9 0.7 1.1e-06 28.3 0.7 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PVD28226.1 - 4.1e-07 29.8 1.9 8.9e-07 28.7 1.9 1.6 1 0 0 1 1 1 1 F-box-like DUF4508 PF14969.6 PVD28226.1 - 0.0011 19.2 2.4 0.0087 16.3 2.2 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4508) IQ_SEC7_PH PF16453.5 PVD28226.1 - 0.03 14.3 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF3292 PF11696.8 PVD28226.1 - 0.045 12.1 0.2 0.082 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Dpy-30 PF05186.13 PVD28226.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Dpy-30 motif Glyco_transf_92 PF01697.27 PVD28227.1 - 3.4e-33 115.4 0.0 8.6e-33 114.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 PVD28228.1 - 2.9e-40 138.6 0.3 4.4e-40 138.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28228.1 - 1.1e-05 25.9 0.0 2.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PVD28229.1 - 4.8e-73 246.0 6.0 1.1e-38 133.4 1.8 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28229.1 - 6.6e-12 45.8 0.3 8.4e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 RNA_pol_Rpb1_3 PF04983.18 PVD28229.1 - 0.0048 16.8 0.1 3.6 7.5 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 3 FragX_IP PF05994.11 PVD28229.1 - 0.0069 14.5 0.3 2 6.4 0.1 2.1 2 0 0 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF3782 PF12644.7 PVD28229.1 - 0.0075 16.4 0.0 7.7 6.7 0.0 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3782) COP23 PF14218.6 PVD28229.1 - 0.11 12.3 0.0 19 5.0 0.0 2.6 2 0 0 2 2 2 0 Circadian oscillating protein COP23 DUF2153 PF09921.9 PVD28229.1 - 0.11 12.3 1.1 2.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) CHASE9 PF17153.4 PVD28229.1 - 0.16 12.1 0.8 9.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular Glyco_transf_92 PF01697.27 PVD28230.1 - 1.4e-19 70.8 0.0 2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 CH PF00307.31 PVD28231.1 - 1.2e-21 76.9 0.0 2.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 PVD28231.1 - 1.4e-09 37.4 0.6 2e-09 36.9 0.6 1.3 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 PVD28231.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain GTF2I PF02946.14 PVD28234.1 - 3e-12 46.4 0.1 6.7e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 GTF2I-like repeat BIR PF00653.21 PVD28235.1 - 9e-27 93.5 9.3 3.3e-19 69.3 0.5 3.1 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD28235.1 - 6.7e-09 35.5 2.1 6.7e-09 35.5 2.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28235.1 - 0.00023 20.9 1.1 0.00023 20.9 1.1 2.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 PVD28235.1 - 0.00046 20.2 0.3 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 C3HC zinc finger-like Pkinase PF00069.25 PVD28237.1 - 4.6e-47 160.6 0.0 4.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD28237.1 - 9.2e-26 90.7 0.0 9.6e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD28237.1 - 3.9e-09 36.2 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD28237.1 - 4.8e-06 26.1 0.2 6.2e-06 25.7 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD28237.1 - 0.00039 19.5 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD28237.1 - 0.00045 20.2 0.0 0.00058 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PVD28237.1 - 0.0011 18.6 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PVD28237.1 - 0.0017 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PVD28237.1 - 0.086 11.6 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 PVD28237.1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S20p PF01649.18 PVD28237.1 - 0.15 12.7 0.0 0.22 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 DUF3482 PF11981.8 PVD28239.1 - 0.019 14.4 1.4 0.022 14.1 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) PAN_1 PF00024.26 PVD28240.1 - 8e-19 67.4 31.3 9.3e-09 35.1 1.9 4.4 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 PVD28240.1 - 0.00011 22.1 24.7 0.19 11.6 0.7 5.0 4 1 1 5 5 5 4 PAN domain PAN_2 PF08276.11 PVD28240.1 - 8.1 6.7 34.1 0.11 12.7 1.3 5.0 3 2 1 5 5 5 0 PAN-like domain D_CNTX PF17492.2 PVD28240.1 - 9.7 6.5 13.0 3.8 7.8 3.3 3.5 3 0 0 3 3 3 0 Delta Ctenitoxins Sulfatase PF00884.23 PVD28241.1 - 1.9e-59 201.6 0.1 2.5e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 PVD28241.1 - 8e-06 25.7 0.0 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function Sulfatase_C PF14707.6 PVD28241.1 - 2.2e-05 25.2 0.0 3.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 PVD28241.1 - 2.3e-05 24.2 0.3 0.00017 21.3 0.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD28241.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 PVD28241.1 - 0.0021 16.8 0.0 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4763 PF15960.5 PVD28241.1 - 0.012 15.0 0.2 0.017 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4976 PF16347.5 PVD28241.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) zf-C2H2 PF00096.26 PVD28242.1 - 1.5e-20 72.5 66.5 0.00016 21.9 0.3 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD28242.1 - 2.7e-17 62.0 65.9 0.0065 17.2 2.5 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD28242.1 - 3.2e-16 58.9 60.5 8e-06 26.1 2.9 8.2 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD28242.1 - 2.8e-05 24.3 38.8 0.35 11.2 0.2 8.1 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 PVD28242.1 - 0.00076 19.5 30.0 0.019 15.0 0.9 5.6 3 2 1 4 4 4 3 BED zinc finger zf-C2H2_6 PF13912.6 PVD28242.1 - 0.00084 19.3 54.4 0.0052 16.8 0.2 7.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 PVD28242.1 - 1.2 9.6 47.8 0.5 10.8 1.6 8.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD28242.1 - 3.4 7.5 19.1 6.1 6.7 0.6 5.3 4 0 0 4 4 4 0 zinc-finger C2H2-type VPS13 PF16908.5 PVD28243.1 - 1.4e-61 208.4 6.2 4e-61 206.8 1.5 3.6 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PVD28243.1 - 1.4e-52 178.8 0.0 6.1e-51 173.4 0.0 2.5 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 PVD28243.1 - 4.6e-41 140.8 5.5 3.4e-33 115.0 0.1 5.7 6 1 0 6 6 6 3 Repeating coiled region of VPS13 Chorein_N PF12624.7 PVD28243.1 - 3.9e-35 120.5 1.0 1.5e-34 118.6 1.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PVD28243.1 - 8.6e-24 84.3 5.5 2e-20 73.3 0.8 3.8 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal UBA PF00627.31 PVD28243.1 - 1.2e-07 31.5 0.1 2.7e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain SUIM_assoc PF16619.5 PVD28243.1 - 1.2 9.3 8.0 1 9.5 4.8 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_7 PF13499.6 PVD28244.1 - 1.4e-05 25.5 0.7 2.4e-05 24.7 0.7 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD28244.1 - 4.7e-05 22.6 2.7 0.0019 17.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PVD28244.1 - 0.0051 17.1 0.1 0.0093 16.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 PVD28244.1 - 0.073 12.9 0.5 0.33 10.8 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair Snapin_Pallidin PF14712.6 PVD28244.1 - 0.15 12.5 0.7 0.37 11.2 0.1 1.8 1 1 1 2 2 2 0 Snapin/Pallidin CMS1 PF14617.6 PVD28247.1 - 9e-30 103.8 19.4 1.3e-28 100.0 19.4 2.6 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 PVD28247.1 - 1.8e-05 24.6 0.2 2.9e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 PVD28247.1 - 1.4 7.1 8.9 2 6.6 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FRG2 PF15315.6 PVD28247.1 - 5.5 7.1 13.5 2.7 8.2 8.7 2.4 3 0 0 3 3 3 0 Facioscapulohumeral muscular dystrophy candidate 2 Presenilin PF01080.17 PVD28247.1 - 7.5 5.2 7.3 10 4.7 7.3 1.1 1 0 0 1 1 1 0 Presenilin Sulfatase PF00884.23 PVD28248.1 - 7.3e-38 130.7 0.2 2.1e-35 122.6 0.0 2.0 2 0 0 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 PVD28249.1 - 0.03 15.1 0.0 0.042 14.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF485 PF04341.12 PVD28252.1 - 0.37 10.8 4.9 0.79 9.7 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Glyco_hydro_56 PF01630.18 PVD28253.1 - 3.3e-74 249.9 0.3 5.5e-74 249.2 0.3 1.2 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 PVD28253.1 - 0.0033 17.7 0.7 0.018 15.3 0.7 2.2 1 1 0 1 1 1 1 EGF-like domain DUF1889 PF08986.10 PVD28253.1 - 0.036 14.5 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) EGF_2 PF07974.13 PVD28253.1 - 0.053 13.9 3.2 0.95 9.9 3.2 2.7 1 1 0 1 1 1 0 EGF-like domain Glyco_hydro_56 PF01630.18 PVD28254.1 - 1.4e-82 277.4 0.0 4.4e-82 275.8 0.0 1.6 1 1 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.13 PVD28254.1 - 0.15 12.5 11.7 1.9 8.9 1.5 3.3 3 0 0 3 3 3 0 EGF-like domain EGF PF00008.27 PVD28254.1 - 0.55 10.6 5.7 9.3 6.7 0.4 3.0 3 0 0 3 3 3 0 EGF-like domain Glyco_hydro_47 PF01532.20 PVD28255.1 - 2.9e-155 517.7 2.5 3.5e-155 517.4 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 PVD28255.1 - 0.2 11.1 2.9 0.5 9.8 0.9 2.6 2 1 1 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Phage_TTP_12 PF16461.5 PVD28260.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP SOBP PF15279.6 PVD28262.1 - 4.5e-37 129.4 17.2 4.5e-37 129.4 17.2 3.3 2 1 0 2 2 2 1 Sine oculis-binding protein UCR_Fe-S_N PF10399.9 PVD28262.1 - 0.041 13.2 1.4 0.095 12.1 1.4 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal zf-FCS PF06467.14 PVD28262.1 - 0.38 10.7 3.2 0.87 9.6 3.2 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif SAP18 PF06487.12 PVD28264.1 - 8.1e-19 68.2 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GCP_C_terminal PF04130.13 PVD28265.1 - 1.8e-77 260.8 15.0 2.1e-77 260.6 12.4 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PVD28265.1 - 1.4e-52 179.3 4.2 4.1e-37 128.5 0.5 3.3 2 1 1 3 3 3 2 Gamma tubulin complex component N-terminal DUF1778 PF08681.11 PVD28265.1 - 0.13 12.3 0.9 0.71 9.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) DUF4241 PF14025.6 PVD28266.1 - 0.16 12.2 0.1 0.44 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Peptidase_C48 PF02902.19 PVD28267.1 - 1.1e-38 133.2 0.0 3e-38 131.8 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KRE1 PF17056.5 PVD28267.1 - 0.051 13.3 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 WD40 PF00400.32 PVD28268.1 - 6.5e-25 86.9 4.4 0.00049 20.9 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28268.1 - 2.8e-07 30.7 0.0 0.021 15.1 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_19 PF14559.6 PVD28268.1 - 1.5e-06 28.6 0.2 0.004 17.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD28268.1 - 1e-05 25.1 0.1 0.00021 20.9 0.2 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 PVD28268.1 - 2e-05 24.4 5.6 0.38 11.0 0.0 4.4 4 1 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD28268.1 - 0.00011 22.4 2.3 0.0014 18.8 1.4 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PVD28268.1 - 0.00012 21.8 8.4 0.13 12.1 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD28268.1 - 0.00066 20.2 0.0 1.2 9.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD28268.1 - 0.0013 19.3 0.1 0.62 11.0 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD28268.1 - 0.0017 18.6 0.0 1.8 9.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD28268.1 - 0.0017 18.6 1.9 2.5 8.4 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 PVD28268.1 - 0.0021 18.0 0.5 0.0048 16.9 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD28268.1 - 0.0087 16.2 0.1 0.17 12.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HEPN PF05168.14 PVD28268.1 - 0.038 14.1 0.7 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 HEPN domain BTB PF00651.31 PVD28269.1 - 6.3e-21 74.7 0.3 1.9e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD28269.1 - 4.7e-17 62.0 3.0 9.5e-15 54.6 1.3 2.9 2 0 0 2 2 2 2 BTB And C-terminal Kelch SdpA PF17418.2 PVD28269.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation delaying protein SdpA Eclosion PF04736.12 PVD28269.1 - 0.13 12.0 0.6 2.6 7.8 0.1 2.7 2 1 0 2 2 2 0 Eclosion hormone CUE PF02845.16 PVD28270.1 - 8.3e-16 57.4 0.4 2.1e-15 56.1 0.1 1.8 2 0 0 2 2 2 1 CUE domain C2 PF00168.30 PVD28270.1 - 0.00012 22.3 0.0 0.18 12.1 0.0 2.3 1 1 1 2 2 2 2 C2 domain HTH_8 PF02954.19 PVD28270.1 - 0.12 12.2 0.7 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family PAPA-1 PF04795.12 PVD28270.1 - 0.2 12.5 0.1 1.2 10.0 0.0 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region DND1_DSRM PF14709.7 PVD28271.1 - 2.5e-14 53.3 0.1 6.9e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 PVD28271.1 - 2.9e-14 53.5 0.1 2.9e-14 53.5 0.1 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif G-patch PF01585.23 PVD28271.1 - 9.5e-14 51.0 3.1 2.1e-13 49.9 3.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD28271.1 - 0.0025 17.9 0.3 0.0025 17.9 0.3 2.9 2 0 0 2 2 2 1 G-patch domain S1-P1_nuclease PF02265.16 PVD28272.1 - 0.014 15.3 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 S1/P1 Nuclease 7tm_1 PF00001.21 PVD28273.1 - 0.004 16.5 1.2 0.0057 16.0 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD28274.1 - 4.2e-05 23.0 0.1 5.3e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD28274.1 - 0.005 16.2 0.0 0.005 16.2 0.0 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD28274.1 - 0.018 14.7 1.3 0.034 13.8 1.3 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Rtt106_N PF18215.1 PVD28276.1 - 0.068 12.9 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain FAM117 PF15388.6 PVD28277.1 - 0.0053 16.2 7.5 0.0077 15.7 7.5 1.1 1 0 0 1 1 1 1 Protein Family FAM117 Methyltransf_FA PF12248.8 PVD28277.1 - 0.11 12.9 0.0 1 9.7 0.0 2.2 1 1 0 1 1 1 0 Farnesoic acid 0-methyl transferase DUF2613 PF11021.8 PVD28277.1 - 2.8 8.1 5.3 9.6 6.4 5.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Spaetzle PF16077.5 PVD28280.1 - 0.069 13.7 5.0 0.17 12.4 5.0 1.7 1 1 0 1 1 1 0 Spaetzle Calici_coat_C PF08435.11 PVD28280.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Peptidase_C4 PF00863.19 PVD28283.1 - 2.7 7.2 5.4 86 2.3 0.2 3.9 2 1 1 4 4 4 0 Peptidase family C4 DUF3246 PF11596.8 PVD28285.1 - 6.8 6.1 8.0 17 4.7 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF5302 PF17227.2 PVD28286.1 - 1.9 9.6 5.3 3.2 8.8 3.5 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5302) Aminotran_1_2 PF00155.21 PVD28287.1 - 2.6e-43 148.6 0.0 3.7e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PVD28287.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase LpoB PF13036.6 PVD28287.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB PIG-U PF06728.13 PVD28288.1 - 6.1e-107 358.0 31.7 7.8e-107 357.6 31.7 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 PVD28288.1 - 0.0047 16.7 23.1 0.0089 15.8 23.1 1.7 1 1 0 1 1 1 1 8TM Microsporidial transmembrane domain Peptidase_C1 PF00112.23 PVD28290.1 - 8.6e-54 182.9 1.1 8.6e-54 182.9 1.1 2.1 2 1 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD28290.1 - 5.2e-09 36.4 2.3 5.2e-09 36.4 2.3 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD28290.1 - 0.0041 15.9 0.5 0.0041 15.9 0.5 1.7 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 PVD28291.1 - 5.9e-82 275.0 3.2 9e-82 274.4 3.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD28291.1 - 2.2e-13 50.4 4.9 3.9e-13 49.6 4.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD28291.1 - 0.0013 17.6 2.9 0.011 14.5 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 PVD28292.1 - 2.3e-83 279.6 6.5 3.2e-83 279.1 6.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD28292.1 - 1.6e-09 38.0 1.5 2.9e-09 37.2 1.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD28292.1 - 0.00012 21.0 8.5 0.0042 15.9 0.5 2.9 3 0 0 3 3 3 2 Peptidase C1-like family ParcG PF10274.9 PVD28293.1 - 1.1e-83 279.8 0.0 1.3e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Ribosomal_S15 PF00312.22 PVD28294.1 - 2.1e-15 56.7 2.3 2.1e-15 56.7 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 DNA_primase_S PF01896.19 PVD28294.1 - 0.071 13.2 1.5 0.13 12.3 1.5 1.6 1 1 0 1 1 1 0 DNA primase small subunit HLH PF00010.26 PVD28296.1 - 5.1e-12 45.6 3.8 1.1e-11 44.5 3.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FUSC PF04632.12 PVD28296.1 - 0.92 8.0 4.7 1.2 7.6 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_2 PF12796.7 PVD28297.1 - 6.2e-16 58.8 5.6 1.9e-09 38.0 3.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD28297.1 - 5.3e-13 49.2 0.8 1.7e-08 34.9 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Chromo PF00385.24 PVD28297.1 - 6.9e-13 48.3 2.3 1.7e-12 47.0 2.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 PVD28297.1 - 1.3e-12 47.6 1.9 0.0043 17.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 PVD28297.1 - 1.9e-12 47.1 1.0 4e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD28297.1 - 6.9e-12 44.5 0.7 0.017 15.6 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Tudor-knot PF11717.8 PVD28297.1 - 0.16 11.9 1.2 0.39 10.7 0.4 2.1 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Fer2 PF00111.27 PVD28298.1 - 2.7e-08 33.6 0.1 3.5e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3449 PF11931.8 PVD28299.1 - 1.4e-74 249.9 0.7 1.4e-74 249.9 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 PVD28299.1 - 3e-30 103.6 1.7 8.1e-30 102.3 1.7 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 PVD28299.1 - 2.6e-22 79.1 4.8 6.8e-22 77.8 4.8 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 EBV-NA3 PF05009.12 PVD28299.1 - 0.047 13.2 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SF3a60_bindingd PF12108.8 PVD28299.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain zf-met PF12874.7 PVD28299.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MGC-24 PF05283.11 PVD28300.1 - 2e-11 44.5 0.1 5.3e-11 43.1 0.0 1.7 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF702 PF05142.12 PVD28300.1 - 0.0064 17.0 0.5 0.0097 16.4 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Topoisom_I_N PF02919.15 PVD28300.1 - 0.093 12.2 1.0 0.14 11.7 1.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment MGC-24 PF05283.11 PVD28301.1 - 2e-06 28.3 10.9 2e-06 28.3 10.9 2.5 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR19-TM PF15176.6 PVD28301.1 - 0.034 14.2 0.1 0.085 12.9 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Fibritin_C PF07921.12 PVD28301.1 - 0.085 13.0 13.9 0.081 13.1 3.5 2.8 1 1 2 3 3 3 0 Fibritin C-terminal region RIFIN PF02009.16 PVD28301.1 - 0.25 11.2 4.2 0.31 10.9 4.2 1.1 1 0 0 1 1 1 0 Rifin PCC_BT PF18140.1 PVD28301.1 - 0.69 10.3 6.2 1.2 9.5 6.2 1.5 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Glyoxalase PF00903.25 PVD28302.1 - 2.8e-09 37.2 0.0 0.0039 17.4 0.1 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PVD28302.1 - 0.0092 16.2 0.3 0.26 11.6 0.0 2.8 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 PVD28304.1 - 1.1e-07 32.1 0.5 0.034 14.3 0.0 3.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pro_isomerase PF00160.21 PVD28305.1 - 4.8e-43 147.2 0.0 6.5e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_jaz PF12171.8 PVD28305.1 - 0.095 13.0 0.6 0.22 11.8 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Tctex-1 PF03645.13 PVD28306.1 - 2.3e-18 66.3 0.2 3.2e-18 65.9 0.2 1.2 1 0 0 1 1 1 1 Tctex-1 family Agglutinin_C PF18021.1 PVD28306.1 - 0.087 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Agglutinin C-terminal SASA PF03629.18 PVD28307.1 - 3.4e-12 46.5 0.0 1.1e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Fibrinogen_BP PF08017.11 PVD28308.1 - 1.2e-16 60.1 85.3 6.4e-12 44.6 41.4 5.8 1 1 5 6 6 6 4 Fibrinogen binding protein HMG_box PF00505.19 PVD28309.1 - 0.031 14.7 1.0 0.19 12.2 0.9 2.4 1 1 1 2 2 2 0 HMG (high mobility group) box GTF2I PF02946.14 PVD28309.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat Las1 PF04031.13 PVD28310.1 - 3.7e-39 134.3 0.4 6.3e-39 133.5 0.4 1.4 1 0 0 1 1 1 1 Las1-like SH2 PF00017.24 PVD28312.1 - 0.19 11.8 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 SH2 domain PDZ_6 PF17820.1 PVD28313.1 - 1e-11 44.5 0.1 2e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD28313.1 - 2.9e-09 37.1 0.1 5.8e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD28313.1 - 3e-07 30.7 0.1 7e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 PDZ domain RhoGEF PF00621.20 PVD28313.1 - 2e-05 24.9 0.0 0.002 18.4 0.0 2.4 1 1 1 2 2 2 1 RhoGEF domain PH PF00169.29 PVD28313.1 - 0.00024 21.6 0.0 0.00056 20.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 PVD28313.1 - 0.04 13.8 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 PH domain Tricorn_PDZ PF14685.6 PVD28313.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain Thiolase_N PF00108.23 PVD28315.1 - 1.2e-35 123.2 1.6 1.4e-35 122.9 1.6 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD28316.1 - 2e-50 169.6 1.0 3.3e-50 168.9 1.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 PVD28316.1 - 5.1e-50 170.2 0.1 8.1e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III_C PF08541.10 PVD28316.1 - 0.031 14.4 1.9 0.036 14.2 0.2 2.0 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Myosin_head PF00063.21 PVD28317.1 - 2.2e-238 792.9 2.1 2.2e-238 792.9 2.1 2.0 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 PVD28317.1 - 4.2e-43 145.2 0.4 5e-42 141.8 0.1 2.8 2 0 0 2 2 2 1 Myosin VI cargo binding domain Myosin_N PF02736.19 PVD28317.1 - 0.00055 19.7 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 PVD28317.1 - 0.032 14.5 5.5 0.65 10.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD28317.1 - 0.035 14.5 0.0 0.035 14.5 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain Baculo_PEP_C PF04513.12 PVD28317.1 - 1.6 8.7 6.6 3.5 7.7 6.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus VIT PF08487.10 PVD28318.1 - 4.9e-43 145.8 0.0 1.3e-42 144.5 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PVD28318.1 - 4.1e-24 85.3 0.0 9.5e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PARP PF00644.20 PVD28318.1 - 1.5e-23 83.4 1.4 1.7e-19 70.2 0.0 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain VIT_2 PF13757.6 PVD28318.1 - 2.9e-15 55.9 0.6 7.4e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 PVD28318.1 - 4.3e-11 43.4 0.0 9.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD28318.1 - 2.5e-08 34.5 0.0 6.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain BRCT PF00533.26 PVD28318.1 - 5e-08 33.2 0.1 1.9e-07 31.3 0.0 2.2 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD28318.1 - 2.7e-06 27.7 0.2 1e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain VWA_CoxE PF05762.14 PVD28318.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein PTCB-BRCT PF12738.7 PVD28318.1 - 0.0016 18.3 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Glyco_hydro_2 PF00703.21 PVD28318.1 - 0.24 12.1 1.0 15 6.3 0.0 3.4 3 0 0 3 3 3 0 Glycosyl hydrolases family 2 Glyco_transf_92 PF01697.27 PVD28320.1 - 5.7e-38 131.0 0.2 9.2e-38 130.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28320.1 - 0.00079 19.9 0.9 0.009 16.5 0.1 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Bcl-2 PF00452.19 PVD28323.1 - 6.6e-10 39.6 0.2 1.2e-09 38.8 0.2 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Peptidase_C10 PF01640.17 PVD28323.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase C10 family HEXIM PF15313.6 PVD28324.1 - 0.059 13.6 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein vATP-synt_E PF01991.18 PVD28325.1 - 4.1e-62 209.2 13.6 5.5e-62 208.7 13.6 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Cytochrome_cB PF11783.8 PVD28325.1 - 0.022 14.6 0.2 0.027 14.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial DUF4288 PF14119.6 PVD28325.1 - 0.06 13.8 1.8 0.16 12.4 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) ThrE PF06738.12 PVD28325.1 - 0.15 11.4 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Ras PF00071.22 PVD28326.1 - 8.1e-16 58.0 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 PVD28326.1 - 0.0025 17.3 0.1 0.0037 16.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_31 PF13614.6 PVD28326.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRORP PF16953.5 PVD28326.1 - 0.13 11.7 0.3 0.77 9.2 0.1 1.9 1 1 1 2 2 2 0 Protein-only RNase P Smg8_Smg9 PF10220.9 PVD28328.1 - 0.0033 15.8 0.0 0.0046 15.4 0.0 1.1 1 0 0 1 1 1 1 Smg8_Smg9 ABC_tran PF00005.27 PVD28328.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 PVD28328.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DRIM PF07539.12 PVD28329.1 - 7.9e-145 483.6 3.0 7.9e-145 483.6 3.0 4.7 3 2 0 3 3 3 1 Down-regulated in metastasis CTP_synth_N PF06418.14 PVD28329.1 - 1e-121 405.3 0.2 1.7e-121 404.5 0.2 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 PVD28329.1 - 1.6e-53 181.3 0.0 4.2e-53 179.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PVD28329.1 - 5.4e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 PVD28329.1 - 0.00099 19.2 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain HEAT PF02985.22 PVD28329.1 - 0.0062 16.7 0.0 56 4.4 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat DUF4062 PF13271.6 PVD28330.1 - 1e-12 48.2 0.0 3.8e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.12 PVD28330.1 - 1.8e-09 37.7 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 PVD28330.1 - 2.9e-08 34.3 0.2 1.7e-06 28.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD28330.1 - 6e-07 29.8 0.0 5e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 PVD28330.1 - 0.00035 20.6 0.0 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 PVD28330.1 - 0.0031 16.8 0.0 0.0079 15.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.17 PVD28330.1 - 0.0095 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF4219 PF13961.6 PVD28330.1 - 0.037 13.7 1.0 0.12 12.1 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) AAA_19 PF13245.6 PVD28330.1 - 0.14 12.5 0.0 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3322 PF11795.8 PVD28330.1 - 0.23 11.4 3.5 0.78 9.7 0.0 3.2 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Tub PF01167.18 PVD28331.1 - 1.1e-92 310.1 0.0 1.6e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Tub family Tub_N PF16322.5 PVD28331.1 - 2.7e-05 24.7 13.5 0.00029 21.3 13.4 2.1 1 1 0 1 1 1 1 Tubby N-terminal Tim17 PF02466.19 PVD28332.1 - 3.4e-09 37.1 0.2 1.8e-08 34.8 0.1 2.1 3 0 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family YhhN PF07947.14 PVD28332.1 - 0.0053 16.4 0.2 0.0086 15.7 0.2 1.4 1 0 0 1 1 1 1 YhhN family DUF4131 PF13567.6 PVD28332.1 - 0.36 10.5 2.2 1.8 8.2 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) C1q PF00386.21 PVD28333.1 - 3.3e-21 75.8 0.0 4.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 C1q domain 7tm_1 PF00001.21 PVD28334.1 - 3.1e-36 125.1 8.0 4e-36 124.7 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD28334.1 - 3.8e-05 23.6 9.7 8.1e-05 22.5 9.7 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 PVD28334.1 - 6e-05 22.5 10.4 0.00012 21.6 10.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 PVD28334.1 - 0.00055 19.4 9.5 0.00083 18.8 9.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD28334.1 - 0.0024 17.6 17.0 0.0074 15.9 17.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4448 PF14610.6 PVD28337.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Y_phosphatase PF00102.27 PVD28338.1 - 9.8e-42 143.1 0.3 2.8e-41 141.7 0.3 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD28338.1 - 4.2e-35 120.0 28.4 2.4e-08 34.2 0.3 8.6 7 1 0 7 7 7 6 Fibronectin type III domain EB PF01683.18 PVD28338.1 - 6.9e-05 23.1 3.7 0.00028 21.1 3.7 2.1 1 0 0 1 1 1 1 EB module SKG6 PF08693.10 PVD28338.1 - 0.01 15.2 1.2 0.025 14.0 1.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_4 PF13418.6 PVD28339.1 - 2.4e-24 85.1 17.5 4.7e-11 42.5 0.3 4.7 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD28339.1 - 1e-18 67.1 18.5 4.1e-05 23.7 0.6 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD28339.1 - 3.6e-15 55.3 11.9 2.4e-08 33.4 0.1 4.0 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 PVD28339.1 - 5.5e-13 48.7 11.8 3.4e-06 27.1 0.1 4.8 3 2 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 PVD28339.1 - 9.2e-12 44.7 6.3 0.00077 19.4 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 PVD28339.1 - 3.2e-09 36.4 11.3 0.0016 18.3 0.1 4.6 5 0 0 5 5 5 3 Kelch motif Cadherin PF00028.17 PVD28340.1 - 8.8e-37 125.5 14.0 1.1e-07 32.2 0.1 7.5 6 1 0 6 6 6 6 Cadherin domain DAG1 PF05454.11 PVD28340.1 - 0.00016 21.1 0.5 0.00047 19.6 0.5 1.7 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.12 PVD28340.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 PVD28340.1 - 0.0098 15.8 8.0 0.013 15.4 1.4 2.8 2 1 0 2 2 2 1 TMEM154 protein family DUF5305 PF17231.2 PVD28340.1 - 0.011 15.2 1.2 0.35 10.2 0.3 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 PVD28340.1 - 0.025 15.4 0.0 0.066 14.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 PVD28340.1 - 0.026 14.8 0.1 0.087 13.1 0.1 1.9 1 0 0 1 1 1 0 Glycophorin A YajC PF02699.15 PVD28340.1 - 0.045 13.6 0.2 0.15 12.0 0.2 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit Shisa PF13908.6 PVD28340.1 - 0.051 13.8 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Mito_fiss_reg PF05308.11 PVD28340.1 - 0.061 13.4 7.3 0.17 12.0 7.3 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator S1FA PF04689.13 PVD28340.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA CHASE PF03924.13 PVD28340.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 CHASE domain DUF4446 PF14584.6 PVD28340.1 - 0.073 13.1 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ninjurin PF04923.12 PVD28340.1 - 0.074 13.0 1.5 0.23 11.4 0.2 2.4 2 0 0 2 2 2 0 Ninjurin DUF4064 PF13273.6 PVD28340.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) LPG_synthase_TM PF03706.13 PVD28340.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region PIRT PF15099.6 PVD28340.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4381 PF14316.6 PVD28340.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CAP_N PF01213.19 PVD28340.1 - 1.2 8.6 13.9 2.5 7.5 13.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cadherin PF00028.17 PVD28341.1 - 1e-70 234.2 52.2 3.6e-07 30.6 0.1 17.4 14 7 1 15 15 15 14 Cadherin domain Cadherin_3 PF16184.5 PVD28341.1 - 2.1e-11 43.8 42.1 0.023 14.7 0.4 9.8 9 0 0 9 9 9 5 Cadherin-like CD34_antigen PF06365.12 PVD28341.1 - 0.00044 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family DAG1 PF05454.11 PVD28341.1 - 0.0017 17.8 0.5 0.0078 15.6 0.1 2.2 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) MOSC PF03473.17 PVD28341.1 - 0.0026 17.8 1.8 14 5.7 0.0 5.3 6 0 0 6 6 6 1 MOSC domain PIRT PF15099.6 PVD28341.1 - 0.014 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Y_Y_Y PF07495.13 PVD28341.1 - 2.2 8.3 14.1 19 5.3 0.1 7.0 7 0 0 7 7 7 0 Y_Y_Y domain DUF1643 PF07799.12 PVD28341.1 - 2.7 8.2 4.7 8.7 6.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1643) Cadherin_pro PF08758.11 PVD28341.1 - 5.2 7.3 7.9 33 4.7 0.3 5.0 5 0 0 5 5 5 0 Cadherin prodomain like Lir1 PF07207.11 PVD28341.1 - 5.9 7.2 8.2 5 7.4 0.2 3.2 3 0 0 3 3 3 0 Light regulated protein Lir1 Cadherin PF00028.17 PVD28342.1 - 1.5e-82 272.1 67.2 9.6e-07 29.2 0.0 20.4 19 5 0 19 19 19 16 Cadherin domain DUF3006 PF11213.8 PVD28342.1 - 0.00025 21.2 0.8 17 5.7 0.0 5.4 6 0 0 6 6 6 1 Protein of unknown function (DUF3006) Cadherin_pro PF08758.11 PVD28342.1 - 0.023 14.9 0.9 14 5.9 0.0 4.2 3 0 0 3 3 3 0 Cadherin prodomain like Pinin_SDK_memA PF04696.13 PVD28342.1 - 0.061 13.4 2.0 0.13 12.3 2.0 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4064 PF13273.6 PVD28342.1 - 0.084 13.2 1.2 0.26 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF5585 PF17823.1 PVD28343.1 - 6.1e-05 22.2 0.0 6.1e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF5585) Cadherin_C_2 PF16492.5 PVD28343.1 - 0.0078 16.9 0.6 0.021 15.6 0.1 1.9 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal SH3_4 PF06347.13 PVD28343.1 - 0.091 12.6 0.5 18 5.2 0.1 3.1 3 0 0 3 3 3 0 Bacterial SH3 domain Cadherin PF00028.17 PVD28344.1 - 1.5e-38 131.2 14.3 1.2e-07 32.1 0.1 7.4 6 1 0 6 6 6 5 Cadherin domain DAG1 PF05454.11 PVD28344.1 - 0.00018 21.0 0.2 0.00052 19.5 0.2 1.7 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.12 PVD28344.1 - 0.00085 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 PVD28344.1 - 0.012 15.5 8.7 0.023 14.6 2.8 3.1 2 1 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 PVD28344.1 - 0.029 15.3 0.0 0.07 14.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_pro PF08758.11 PVD28344.1 - 0.031 14.5 0.3 4.6 7.5 0.0 3.7 4 0 0 4 4 3 0 Cadherin prodomain like Shisa PF13908.6 PVD28344.1 - 0.032 14.5 0.1 0.11 12.7 0.1 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 PVD28344.1 - 0.032 14.5 0.1 0.095 12.9 0.1 1.8 1 0 0 1 1 1 0 Glycophorin A YajC PF02699.15 PVD28344.1 - 0.048 13.5 0.2 0.16 11.9 0.2 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit S1FA PF04689.13 PVD28344.1 - 0.066 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA CHASE PF03924.13 PVD28344.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 CHASE domain DUF4064 PF13273.6 PVD28344.1 - 0.068 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4446 PF14584.6 PVD28344.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LPG_synthase_TM PF03706.13 PVD28344.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Ninjurin PF04923.12 PVD28344.1 - 0.11 12.5 1.3 0.24 11.3 0.2 2.1 2 0 0 2 2 2 0 Ninjurin PIRT PF15099.6 PVD28344.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4381 PF14316.6 PVD28344.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Mito_fiss_reg PF05308.11 PVD28344.1 - 0.82 9.7 9.8 2.1 8.4 9.8 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD28344.1 - 2.1 7.7 15.0 4.6 6.6 15.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cadherin PF00028.17 PVD28345.1 - 3e-79 261.5 66.4 2.5e-07 31.0 0.1 21.1 17 7 1 19 19 19 16 Cadherin domain DAG1 PF05454.11 PVD28345.1 - 0.00066 19.1 0.1 0.0023 17.4 0.1 1.9 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.12 PVD28345.1 - 0.00078 19.1 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF249 PF03158.13 PVD28345.1 - 0.013 15.2 1.4 58 3.3 0.0 4.8 5 0 0 5 5 5 0 Multigene family 530 protein PIRT PF15099.6 PVD28345.1 - 0.022 14.3 0.0 0.064 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Sina PF03145.16 PVD28345.1 - 0.094 12.6 7.7 10 6.0 0.0 4.5 5 0 0 5 5 5 0 Seven in absentia protein family DUF2380 PF09533.10 PVD28345.1 - 0.12 11.9 2.4 0.46 10.1 0.4 2.4 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) EphA2_TM PF14575.6 PVD28345.1 - 0.13 13.2 0.0 0.32 11.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MRP_L53 PF10780.9 PVD28345.1 - 0.72 10.1 13.7 57 4.0 0.1 6.1 6 0 0 6 6 6 0 39S ribosomal protein L53/MRP-L53 CAP_N PF01213.19 PVD28345.1 - 1.3 8.4 3.0 2.3 7.6 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PVD28345.1 - 1.4 9.0 6.2 3.9 7.5 4.4 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Cadherin PF00028.17 PVD28346.1 - 1.8e-56 188.6 35.9 4.7e-08 33.4 0.1 12.2 10 3 0 10 10 10 10 Cadherin domain Y_Y_Y PF07495.13 PVD28346.1 - 0.0088 16.0 4.3 9.6 6.2 0.3 5.6 5 0 0 5 5 5 1 Y_Y_Y domain DUF1583 PF07622.11 PVD28346.1 - 0.012 14.4 0.1 0.039 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1583) UDPG_MGDP_dh_C PF03720.15 PVD28346.1 - 0.16 12.4 0.3 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sina PF03145.16 PVD28346.1 - 0.39 10.6 2.6 27 4.6 0.0 3.5 4 1 1 5 5 5 0 Seven in absentia protein family Cadherin_pro PF08758.11 PVD28346.1 - 0.5 10.6 4.8 3.4 7.9 0.1 4.1 4 2 0 4 4 4 0 Cadherin prodomain like SEF14_adhesin PF06443.11 PVD28346.1 - 2.4 8.0 4.6 15 5.4 0.1 3.8 4 0 0 4 4 4 0 SEF14-like adhesin Cadherin PF00028.17 PVD28347.1 - 2.5e-32 111.1 31.3 6.7e-08 32.9 0.1 9.3 6 3 3 9 9 9 8 Cadherin domain DUF4064 PF13273.6 PVD28347.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Cadherin PF00028.17 PVD28348.1 - 5e-10 39.7 0.5 3.3e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain CD34_antigen PF06365.12 PVD28348.1 - 0.00027 20.6 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family DAG1 PF05454.11 PVD28348.1 - 0.00027 20.4 0.6 0.0011 18.4 0.3 1.9 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 PVD28348.1 - 0.0056 16.6 1.5 0.0056 16.6 1.5 2.9 2 1 0 2 2 2 1 TMEM154 protein family CitMHS PF03600.16 PVD28348.1 - 0.024 13.9 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter Pinin_SDK_memA PF04696.13 PVD28348.1 - 0.039 14.0 0.4 0.083 13.0 0.4 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Amnionless PF14828.6 PVD28348.1 - 0.041 12.7 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless PIRT PF15099.6 PVD28348.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Glycophorin_A PF01102.18 PVD28348.1 - 0.074 13.3 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Glycophorin A Ninjurin PF04923.12 PVD28348.1 - 0.087 12.8 2.3 0.13 12.2 0.3 2.0 2 0 0 2 2 2 0 Ninjurin DUF2207 PF09972.9 PVD28348.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 PVD28348.1 - 0.12 12.6 1.1 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 PVD28348.1 - 0.13 13.2 0.1 0.36 11.7 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.13 PVD28348.1 - 0.18 12.0 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4446 PF14584.6 PVD28348.1 - 0.2 11.6 0.6 0.43 10.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) NUDIX PF00293.28 PVD28349.1 - 8.8e-17 61.4 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF5585 PF17823.1 PVD28349.1 - 0.0002 20.4 0.0 0.0002 20.4 0.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5585) NUDIX_2 PF13869.6 PVD28349.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Nucleotide hydrolase Cadherin_C_2 PF16492.5 PVD28349.1 - 0.017 15.8 0.1 0.067 13.9 0.1 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 PVD28349.1 - 1.1 9.1 7.7 1.2 9.1 0.0 2.5 1 1 1 2 2 2 0 TMEM154 protein family SOCS_box PF07525.16 PVD28350.1 - 3.9e-10 39.9 4.5 1.1e-09 38.5 4.5 1.8 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD28350.1 - 7.7e-07 29.5 0.3 0.00045 20.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3453 PF11935.8 PVD28350.1 - 0.0015 18.2 1.4 0.0022 17.7 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Ank_2 PF12796.7 PVD28350.1 - 0.0037 17.8 0.2 0.072 13.7 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD28350.1 - 0.037 14.6 0.6 0.83 10.4 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat CUTL PF16557.5 PVD28350.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB FANCI_S2 PF14676.6 PVD28350.1 - 0.27 11.5 1.8 7.2 6.9 0.1 2.9 2 1 1 3 3 3 0 FANCI solenoid 2 Ank PF00023.30 PVD28350.1 - 0.39 11.2 3.2 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Cadherin PF00028.17 PVD28351.1 - 1.4e-25 89.5 0.1 4.1e-08 33.6 0.0 3.7 3 0 0 3 3 3 3 Cadherin domain CD34_antigen PF06365.12 PVD28351.1 - 0.00028 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family Cadherin_3 PF16184.5 PVD28351.1 - 0.0083 16.1 7.8 0.89 9.6 0.1 4.6 4 1 1 5 5 5 1 Cadherin-like EphA2_TM PF14575.6 PVD28351.1 - 0.013 16.3 0.1 0.034 15.0 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PVD28351.1 - 0.028 14.3 1.5 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 51 HemY_N PF07219.13 PVD28351.1 - 0.064 13.5 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.6 PVD28351.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family S1FA PF04689.13 PVD28351.1 - 0.2 11.8 0.1 0.47 10.6 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA DUF1494 PF07379.11 PVD28352.1 - 0.046 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) DUF3185 PF11381.8 PVD28352.1 - 9.2 6.4 7.9 1.2e+02 2.8 4.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) Gal_Lectin PF02140.18 PVD28353.1 - 0.00034 21.0 3.8 0.00034 21.0 3.8 2.3 2 0 0 2 2 2 1 Galactose binding lectin domain EphA2_TM PF14575.6 PVD28353.1 - 0.037 14.9 0.0 0.1 13.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IL1_propep PF02394.16 PVD28353.1 - 0.11 13.5 0.4 0.26 12.2 0.4 1.6 1 0 0 1 1 1 0 Interleukin-1 propeptide DAP10 PF07213.11 PVD28353.1 - 1.3 9.1 4.2 0.43 10.6 0.2 2.2 2 0 0 2 2 2 0 DAP10 membrane protein Importin_rep_6 PF18829.1 PVD28356.1 - 0.016 15.3 0.3 0.019 15.1 0.3 1.1 1 0 0 1 1 1 0 Importin repeat 6 Pkinase PF00069.25 PVD28357.1 - 8.2e-63 212.2 0.4 2.3e-61 207.5 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD28357.1 - 6.6e-29 101.0 0.1 1.3e-20 73.8 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PVD28357.1 - 0.0007 19.6 0.6 0.0093 15.9 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD28357.1 - 0.0021 17.4 0.2 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PVD28357.1 - 0.0025 16.9 0.1 0.0042 16.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain UBA PF00627.31 PVD28357.1 - 0.036 14.0 1.1 0.065 13.1 0.1 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Pox_ser-thr_kin PF05445.11 PVD28357.1 - 0.067 12.2 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 PVD28357.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YBD PF17725.1 PVD28358.1 - 1.2e-76 257.2 0.6 1.7e-76 256.7 0.6 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 PVD28358.1 - 1.9e-27 95.1 0.0 4.4e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Dimer_Tnp_hAT PF05699.14 PVD28359.1 - 0.054 13.3 0.3 0.23 11.3 0.1 2.2 2 1 0 2 2 2 0 hAT family C-terminal dimerisation region Coiled-coil_56 PF09813.9 PVD28359.1 - 0.67 10.0 3.6 0.25 11.4 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 CH PF00307.31 PVD28362.1 - 2.2e-21 76.1 1.6 1.5e-14 54.1 1.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF1938 PF09153.10 PVD28362.1 - 0.008 16.2 0.8 0.047 13.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1938) DUF957 PF06117.11 PVD28362.1 - 0.02 14.4 0.9 0.039 13.5 0.9 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) RecG_N PF17190.4 PVD28362.1 - 0.042 14.6 1.5 0.082 13.6 0.2 2.2 3 1 0 3 3 3 0 RecG N-terminal helical domain HD_assoc PF13286.6 PVD28362.1 - 0.059 13.9 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain CAMSAP_CH PF11971.8 PVD28362.1 - 0.089 12.6 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain TspO_MBR PF03073.15 PVD28363.1 - 4.7e-51 172.4 10.8 5.3e-51 172.2 10.8 1.0 1 0 0 1 1 1 1 TspO/MBR family Cyd_oper_YbgE PF09600.10 PVD28363.1 - 1.5 9.3 8.9 0.41 11.0 5.8 1.8 2 1 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) PhoH PF02562.16 PVD28365.1 - 0.00019 21.0 0.0 0.00025 20.6 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 PVD28365.1 - 0.00028 20.7 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 PVD28365.1 - 0.00085 19.0 0.1 0.0017 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD28365.1 - 0.0096 16.3 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 PVD28365.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PVD28365.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PVD28365.1 - 0.035 13.4 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_8 PF12780.7 PVD28365.1 - 0.061 12.6 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_22 PF13401.6 PVD28365.1 - 0.083 13.2 0.1 0.38 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PVD28365.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PVD28365.1 - 0.14 12.1 0.2 0.21 11.5 0.2 1.6 1 1 0 1 1 1 0 NACHT domain DUF815 PF05673.13 PVD28365.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PVD28365.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Ras PF00071.22 PVD28365.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Ras family DSPc PF00782.20 PVD28366.1 - 8.1e-41 139.0 0.0 1.5e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 PVD28366.1 - 1.5e-07 31.9 0.0 3.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 PVD28366.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NifU_N PF01592.16 PVD28368.1 - 1.3e-53 180.6 0.5 2.5e-51 173.2 0.5 2.0 1 1 0 1 1 1 1 NifU-like N terminal domain Proteasome PF00227.26 PVD28368.1 - 0.073 12.6 0.1 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Proteasome subunit zf-RING_14 PF17978.1 PVD28369.1 - 4.9e-36 123.0 9.5 4.9e-36 123.0 9.5 3.1 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_12 PF17976.1 PVD28369.1 - 2.6e-22 78.8 5.4 2.6e-22 78.8 5.4 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain ubiquitin PF00240.23 PVD28369.1 - 5.9e-09 35.6 0.0 9.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family IBR PF01485.21 PVD28369.1 - 5.3e-08 33.0 6.2 5.3e-08 33.0 6.2 4.4 2 1 2 4 4 4 1 IBR domain, a half RING-finger domain Ubiquitin_5 PF18037.1 PVD28369.1 - 0.0078 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Morc6_S5 PF17942.1 PVD28371.1 - 2.9e-64 215.3 2.8 3.2e-39 134.2 0.5 2.7 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 PVD28371.1 - 1.8e-31 107.9 20.5 3.4e-16 59.0 5.0 2.9 3 0 0 3 3 3 2 CW-type Zinc Finger HATPase_c_3 PF13589.6 PVD28371.1 - 2.3e-19 69.6 0.0 2.8e-08 33.7 0.0 3.1 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2184 PF09950.9 PVD28371.1 - 0.018 14.4 0.2 3.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) HATPase_c PF02518.26 PVD28371.1 - 0.14 12.7 0.0 13 6.3 0.0 3.0 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_C2 PF14533.6 PVD28372.1 - 1.8e-69 233.6 1.4 2.2e-69 233.3 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 PVD28372.1 - 1.8e-32 112.6 0.0 5.2e-32 111.1 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Phlebovirus_G1 PF07243.11 PVD28372.1 - 0.15 10.4 0.1 0.22 9.9 0.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 SET PF00856.28 PVD28373.1 - 1.9e-06 28.4 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PVD28373.1 - 0.012 16.3 0.3 0.022 15.5 0.3 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding DNA_pol_B PF00136.21 PVD28374.1 - 7.8e-91 305.1 0.0 1.1e-90 304.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PVD28374.1 - 8.9e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PVD28374.1 - 0.0001 22.7 4.2 0.00059 20.3 4.2 2.4 1 1 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF4683 PF15735.5 PVD28374.1 - 5 6.7 28.0 0.0068 16.1 3.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4683) DNA_pol_B_exo1 PF03104.19 PVD28376.1 - 2.8e-09 36.6 0.1 4.2e-08 32.7 0.0 2.5 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain T-box PF00907.22 PVD28377.1 - 3.8e-49 167.4 0.0 7.4e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 T-box Glyco_hydro_36C PF16874.5 PVD28377.1 - 0.046 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain 5_nucleotid_C PF02872.18 PVD28378.1 - 2.4e-43 148.1 0.0 4.4e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PVD28378.1 - 6.2e-13 49.7 0.0 1.2e-12 48.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3215 PF11503.8 PVD28378.1 - 0.014 15.3 0.0 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) PGA_cap PF09587.10 PVD28378.1 - 0.29 10.5 1.6 6.5 6.1 1.6 2.3 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap 5_nucleotid_C PF02872.18 PVD28379.1 - 5.4e-44 150.2 0.0 9.2e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PVD28379.1 - 3e-13 50.7 0.0 5.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAM150 PF15129.6 PVD28380.1 - 0.041 14.0 2.1 0.079 13.1 2.1 1.4 1 0 0 1 1 1 0 FAM150 family FAM176 PF14851.6 PVD28380.1 - 0.51 10.0 10.2 1.5 8.4 3.4 2.1 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 PVD28380.1 - 1.1 9.5 14.6 3.4 8.0 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Presenilin PF01080.17 PVD28380.1 - 2.9 6.6 3.4 3.2 6.4 3.4 1.1 1 0 0 1 1 1 0 Presenilin Popeye PF04831.13 PVD28381.1 - 2.3e-32 112.1 3.0 3.5e-32 111.5 3.0 1.3 1 0 0 1 1 1 1 Popeye protein conserved region AbiEi_4 PF13338.6 PVD28381.1 - 0.1 12.7 0.2 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Med6 PF04934.14 PVD28381.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 MED6 mediator sub complex component Myb_DNA-bind_4 PF13837.6 PVD28382.1 - 4.9e-06 26.8 0.2 4.9e-06 26.8 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NAM-associated PF14303.6 PVD28382.1 - 0.00017 22.4 6.2 0.00029 21.6 6.2 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF601 PF04642.12 PVD28382.1 - 0.027 14.0 2.0 0.041 13.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Myb_DNA-bind_6 PF13921.6 PVD28382.1 - 0.035 14.4 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF5529 PF17669.1 PVD28383.1 - 0.00035 20.7 2.9 0.00071 19.7 2.9 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5529) zf-CCHC PF00098.23 PVD28383.1 - 0.00038 20.4 0.9 0.0011 18.9 0.9 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD28383.1 - 0.0037 17.0 1.1 0.0081 16.0 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PVD28383.1 - 0.043 13.6 0.3 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Med6 PF04934.14 PVD28384.1 - 0.059 13.2 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 MED6 mediator sub complex component Popeye PF04831.13 PVD28387.1 - 0.00025 21.2 0.2 0.43 10.7 0.4 2.3 1 1 1 2 2 2 2 Popeye protein conserved region Popeye PF04831.13 PVD28388.1 - 1.9e-35 122.0 0.3 2.9e-35 121.5 0.3 1.2 1 0 0 1 1 1 1 Popeye protein conserved region zf-C3HC4 PF00097.25 PVD28390.1 - 0.00035 20.4 11.7 0.00035 20.4 11.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD28390.1 - 0.0017 18.5 11.7 0.0042 17.2 11.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD28390.1 - 0.0032 17.3 13.4 0.0032 17.3 13.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD28390.1 - 0.0088 15.9 14.3 0.0088 15.9 14.3 2.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28390.1 - 0.014 15.3 13.5 0.014 15.3 13.5 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PVD28390.1 - 0.47 10.6 14.0 0.23 11.6 10.1 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 PVD28390.1 - 0.47 10.8 21.4 0.044 14.1 16.2 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 PVD28390.1 - 0.69 10.0 16.9 2 8.5 16.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_hydro_3 PF00933.21 PVD28391.1 - 1.5e-35 123.1 0.0 3.5e-34 118.6 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 PVD28391.1 - 2.2e-34 119.2 0.0 4.4e-33 114.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 PVD28391.1 - 2.3e-13 50.1 0.0 8.1e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain RWD PF05773.22 PVD28392.1 - 6.2e-25 87.8 5.3 1.1e-24 86.9 5.3 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 PVD28392.1 - 0.00026 21.4 6.6 0.00081 19.8 6.0 2.2 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 TAF4 PF05236.14 PVD28392.1 - 0.024 14.4 0.9 0.031 14.0 0.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2326 PF10088.9 PVD28392.1 - 0.29 10.8 4.6 0.19 11.4 2.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) MRP-S31 PF15433.6 PVD28393.1 - 4.9e-80 269.6 1.4 5.8e-80 269.3 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DUF4701 PF15773.5 PVD28393.1 - 0.004 16.2 8.7 0.0057 15.7 8.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4701) AF-4 PF05110.13 PVD28393.1 - 0.011 13.8 10.9 0.015 13.4 10.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM104 PF15434.6 PVD28393.1 - 0.72 10.4 6.5 0.24 12.0 3.3 1.9 2 0 0 2 2 2 0 Family 104 Glyco_transf_7N PF13733.6 PVD28394.1 - 5.6e-52 174.9 0.0 8.4e-52 174.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD28394.1 - 4.3e-26 90.4 0.1 7.7e-26 89.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase IN_DBD_C PF00552.21 PVD28394.1 - 0.034 13.4 0.6 0.075 12.3 0.6 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain RWD PF05773.22 PVD28396.1 - 7e-08 32.8 3.6 2.1e-05 24.8 1.0 2.7 2 1 1 3 3 3 2 RWD domain DFRP_C PF16543.5 PVD28396.1 - 3.8e-07 30.5 10.3 1.8e-06 28.3 9.9 2.5 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 MRP-S31 PF15433.6 PVD28397.1 - 6.2e-80 269.2 1.5 7.5e-80 269.0 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DUF4701 PF15773.5 PVD28397.1 - 0.0035 16.4 8.6 0.005 15.9 8.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4701) FAM104 PF15434.6 PVD28397.1 - 0.51 10.9 6.7 0.17 12.4 3.4 1.9 2 0 0 2 2 2 0 Family 104 Chorion_2 PF03964.15 PVD28397.1 - 0.7 10.8 5.4 1.6 9.6 0.2 2.6 2 0 0 2 2 2 0 Chorion family 2 Glyco_transf_7N PF13733.6 PVD28398.1 - 3e-51 172.6 0.0 4.4e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD28398.1 - 1.5e-27 95.1 0.1 2.9e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF1981 PF09324.10 PVD28400.1 - 4.6e-07 29.6 0.2 6e-06 26.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 PVD28400.1 - 0.00054 19.9 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TM140 PF14985.6 PVD28400.1 - 0.0023 17.5 0.7 0.0043 16.6 0.0 1.7 2 0 0 2 2 2 1 TM140 protein family DCB PF16213.5 PVD28400.1 - 0.0024 17.6 2.3 0.0049 16.6 0.5 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 RYDR_ITPR PF01365.21 PVD28400.1 - 7.9 5.8 7.0 4.6 6.6 1.1 2.9 3 0 0 3 3 3 0 RIH domain ERM PF00769.19 PVD28401.1 - 3e-44 151.7 63.0 3e-44 151.7 63.0 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 PVD28401.1 - 1.7e-26 92.4 0.0 5.1e-26 90.9 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD28401.1 - 1.4e-24 86.7 0.3 1.4e-24 86.7 0.3 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 PVD28401.1 - 4.9e-14 52.0 0.1 1.5e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain NolV PF06635.12 PVD28402.1 - 0.025 14.0 0.4 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein NolV DUF3987 PF13148.6 PVD28402.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribosomal_S9 PF00380.19 PVD28404.1 - 1.5e-11 44.9 0.1 4.1e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 HSA PF07529.13 PVD28404.1 - 0.077 13.3 2.9 0.22 11.9 2.9 1.7 1 0 0 1 1 1 0 HSA Globin PF00042.22 PVD28405.1 - 9.4e-15 55.1 0.0 1.4e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.22 PVD28406.1 - 3.6e-18 66.1 0.3 4.8e-18 65.7 0.3 1.2 1 0 0 1 1 1 1 Globin TetR_C_11 PF16859.5 PVD28406.1 - 0.15 12.4 1.3 1.1 9.6 0.6 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF21 PF01595.20 PVD28407.1 - 1.2e-32 113.0 1.4 2e-32 112.3 1.4 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PVD28407.1 - 0.14 12.6 3.0 2.1 8.9 1.1 2.9 2 1 0 2 2 2 0 CBS domain BRICHOS PF04089.14 PVD28408.1 - 1.7e-08 34.6 0.0 4.7e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 BRICHOS domain MFS_1 PF07690.16 PVD28409.1 - 4.7e-15 55.4 22.8 2.8e-09 36.4 1.6 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 PVD28409.1 - 0.05 12.4 15.3 0.059 12.2 13.2 2.0 1 1 1 2 2 2 0 MFS_1 like family DUF282 PF03380.14 PVD28409.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.5 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 RNA_polI_A34 PF08208.11 PVD28410.1 - 0.004 17.3 12.9 0.004 17.3 12.9 2.4 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 zf-B_box PF00643.24 PVD28413.1 - 5.8e-08 32.8 13.9 5.8e-08 32.8 13.9 4.4 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 PVD28413.1 - 0.00085 19.2 4.6 0.00085 19.2 4.6 3.9 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD28413.1 - 0.0027 17.6 6.7 0.0027 17.6 6.7 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DHC_N1 PF08385.12 PVD28413.1 - 0.14 10.7 0.8 0.82 8.2 0.1 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 zf-Sec23_Sec24 PF04810.15 PVD28413.1 - 0.98 9.5 0.0 0.98 9.5 0.0 4.0 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger Bd3614-deam PF14439.6 PVD28413.1 - 1.5 8.9 9.3 1.8 8.6 3.4 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase 7TM_GPCR_Srw PF10324.9 PVD28414.1 - 0.00047 19.5 0.2 0.00055 19.3 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2407_C PF13373.6 PVD28414.1 - 0.038 14.2 0.1 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 DUF2407 C-terminal domain 7TM_GPCR_Srx PF10328.9 PVD28415.1 - 1.7e-06 27.9 6.3 3.3e-06 26.9 6.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 PVD28415.1 - 0.0014 17.7 3.2 0.0016 17.4 3.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt Srg PF02118.21 PVD28415.1 - 0.0079 15.9 8.8 0.021 14.5 8.8 1.6 1 1 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srw PF10324.9 PVD28415.1 - 0.011 15.1 3.8 0.015 14.6 3.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD28415.1 - 0.011 15.1 7.3 0.014 14.8 7.3 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD28416.1 - 0.00012 21.6 16.0 0.00022 20.6 16.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD28416.1 - 0.0052 16.4 13.4 0.0052 16.4 13.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx IlvB_leader PF08049.11 PVD28416.1 - 0.3 11.1 3.6 0.92 9.5 3.6 1.8 1 0 0 1 1 1 0 IlvB leader peptide 7TM_GPCR_Srx PF10328.9 PVD28417.1 - 2.5e-05 24.1 14.8 5.7e-05 22.9 14.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx IlvB_leader PF08049.11 PVD28417.1 - 0.034 14.1 1.5 0.11 12.4 1.5 1.9 1 0 0 1 1 1 0 IlvB leader peptide DUF2407_C PF13373.6 PVD28417.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.7 1 1 0 1 1 1 0 DUF2407 C-terminal domain 7TM_GPCR_Srx PF10328.9 PVD28418.1 - 1.3e-06 28.3 10.7 2.5e-06 27.3 10.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD28418.1 - 0.048 13.0 13.8 0.087 12.1 13.8 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sulfatase PF00884.23 PVD28419.1 - 5.1e-69 233.0 0.3 7e-69 232.6 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD28419.1 - 8.1e-06 25.7 0.2 0.00028 20.6 0.1 2.7 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD28419.1 - 0.0072 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF4994 PF16385.5 PVD28419.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 PVD28419.1 - 0.15 12.8 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Glyco_hydro_3 PF00933.21 PVD28420.1 - 9.1e-82 275.0 0.0 3e-46 158.2 0.0 3.9 2 2 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 PVD28420.1 - 1.2e-69 234.4 0.0 1.6e-36 126.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 PVD28420.1 - 1.4e-20 73.2 3.7 7.3e-11 42.0 0.2 3.8 5 0 0 5 5 5 2 Fibronectin type III-like domain DUF3602 PF12223.8 PVD28420.1 - 0.0052 17.4 0.5 6.2 7.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3602) ZipA_C PF04354.13 PVD28420.1 - 0.15 11.9 0.3 21 5.0 0.0 2.3 2 0 0 2 2 2 0 ZipA, C-terminal FtsZ-binding domain TGT PF01702.18 PVD28420.1 - 0.21 10.7 0.0 31 3.6 0.0 2.8 3 0 0 3 3 3 0 Queuine tRNA-ribosyltransferase YccV-like PF08755.11 PVD28421.1 - 6.5e-30 103.5 0.2 1.6e-29 102.3 0.2 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like ADH_zinc_N PF00107.26 PVD28421.1 - 3.5e-20 72.3 0.3 7e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD28421.1 - 8.5e-11 41.7 0.0 3e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PVD28421.1 - 4e-09 37.6 0.0 8.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PVD28421.1 - 0.12 11.6 0.5 0.23 10.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 PVD28422.1 - 1.8e-24 86.2 0.5 3.4e-24 85.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD28422.1 - 1.5e-13 52.0 0.0 3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD28422.1 - 1.3e-11 44.4 0.1 4.5e-11 42.6 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ferritin PF00210.24 PVD28423.1 - 4e-37 127.3 2.9 4.6e-37 127.1 2.9 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 PVD28423.1 - 1.5e-05 25.4 0.4 1.9e-05 25.1 0.4 1.3 1 0 0 1 1 1 1 Rubrerythrin MRP-S33 PF08293.11 PVD28423.1 - 0.039 14.2 0.3 0.081 13.2 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 FCH PF00611.23 PVD28423.1 - 0.19 12.0 1.0 0.42 10.9 1.0 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Ferritin PF00210.24 PVD28424.1 - 2.1e-40 137.9 2.6 2.5e-40 137.7 2.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 PVD28424.1 - 2.9e-05 24.5 0.3 3.7e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Rubrerythrin Gal-bind_lectin PF00337.22 PVD28425.1 - 1.7e-13 50.3 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin zf-C3HC4_3 PF13920.6 PVD28426.1 - 4.3e-16 58.5 33.2 5.7e-09 35.7 8.1 3.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28426.1 - 2.8e-08 33.5 32.6 6.2e-05 22.8 9.3 2.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 BIR PF00653.21 PVD28426.1 - 0.037 14.7 0.3 0.037 14.7 0.3 3.2 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain Vfa1 PF08432.10 PVD28426.1 - 5.3 7.3 5.7 11 6.3 0.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 BIR PF00653.21 PVD28428.1 - 0.018 15.7 0.1 0.047 14.3 0.1 1.8 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28431.1 - 1.1e-25 90.0 0.2 4e-20 72.2 0.3 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28432.1 - 1.3e-05 25.7 3.7 1.3e-05 25.7 3.7 1.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28433.1 - 2.1e-15 57.1 0.3 4.9e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28434.1 - 4e-17 62.6 3.4 1.3e-12 48.1 3.1 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28435.1 - 2.2e-26 92.3 0.2 6.6e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-ribbon_3 PF13248.6 PVD28435.1 - 0.1 12.0 0.6 7.2 6.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Sugar_tr PF00083.24 PVD28436.1 - 1.1e-25 90.4 15.2 1.7e-25 89.8 15.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD28436.1 - 2.5e-16 59.6 21.1 2.5e-16 59.6 21.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 PVD28436.1 - 0.002 17.5 10.6 0.0046 16.3 10.6 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 PVD28437.1 - 4.1e-27 95.1 3.4 2.5e-19 69.5 0.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD28437.1 - 5.9e-15 55.0 20.5 2.5e-09 36.5 6.0 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PVD28437.1 - 0.029 12.8 5.1 0.058 11.8 0.2 2.3 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF5345 PF17280.2 PVD28437.1 - 0.06 13.3 0.2 0.24 11.4 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5345) VIT1 PF01988.19 PVD28437.1 - 6 6.7 9.1 1.9 8.3 0.9 2.7 3 0 0 3 3 3 0 VIT family DUF4706 PF15797.5 PVD28438.1 - 3.6e-21 75.7 6.8 1.2e-20 74.0 1.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4706) Phage_spike PF18715.1 PVD28438.1 - 0.18 11.9 1.7 0.38 10.9 1.7 1.5 1 0 0 1 1 1 0 Phage spike trimer IMS PF00817.20 PVD28439.1 - 7e-24 84.5 0.1 1e-23 84.0 0.1 1.3 1 1 0 1 1 1 1 impB/mucB/samB family Dcc1 PF09724.9 PVD28439.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 DUF1805 PF08827.11 PVD28439.1 - 0.1 12.9 0.2 0.47 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Pkinase PF00069.25 PVD28440.1 - 1.5e-144 480.2 0.0 3.2e-71 239.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD28440.1 - 2e-76 256.7 0.0 5.7e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD28440.1 - 5.9e-12 45.5 0.0 3.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PVD28440.1 - 2.6e-11 43.3 0.0 5.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PVD28440.1 - 7.8e-08 31.5 0.0 0.0053 15.6 0.0 2.5 3 0 0 3 3 3 2 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PVD28440.1 - 9e-07 28.6 0.1 0.0085 15.6 0.0 3.2 2 1 1 3 3 3 2 PhoP regulatory network protein YrbL APH PF01636.23 PVD28440.1 - 1.6e-05 24.9 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 PVD28440.1 - 5e-05 23.9 1.5 0.0002 22.0 1.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 PVD28440.1 - 0.00016 20.7 0.2 0.011 14.7 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 PVD28440.1 - 0.00026 20.7 0.0 2.6 7.6 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PVD28440.1 - 0.025 14.2 0.3 0.99 9.0 0.0 2.6 3 0 0 3 3 3 0 RIO1 family tRNA-synt_1f PF01921.18 PVD28440.1 - 0.051 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Glycos_transf_3 PF00591.21 PVD28441.1 - 8.2e-26 91.1 0.5 1.3e-25 90.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 PVD28441.1 - 7.8e-22 76.9 0.1 1.5e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain TRAPPC10 PF12584.8 PVD28442.1 - 6e-12 45.5 0.0 1.9e-11 43.9 0.0 1.9 1 1 1 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 PVD28442.1 - 1.3e-06 28.2 0.6 2.1e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 Foie gras liver health family 1 TPR_14 PF13428.6 PVD28442.1 - 0.02 15.7 0.2 0.14 13.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat 3HCDH_N PF02737.18 PVD28443.1 - 6.7e-47 159.7 0.0 9.2e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PVD28443.1 - 2e-13 50.8 0.0 4.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 PVD28443.1 - 0.00021 20.9 0.2 0.00041 20.0 0.2 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 PVD28443.1 - 0.00026 21.2 0.1 0.00052 20.2 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PVD28443.1 - 0.00072 19.0 0.1 0.0012 18.3 0.1 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PVD28443.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 PVD28443.1 - 0.0046 16.6 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 PVD28443.1 - 0.039 13.2 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD28443.1 - 0.073 13.6 0.1 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PVD28443.1 - 0.09 12.1 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 PVD28443.1 - 0.17 11.3 0.1 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 PVD28444.1 - 1e-44 152.6 0.0 1.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PVD28444.1 - 3.1e-11 43.7 0.6 6.9e-11 42.6 0.1 1.9 2 1 1 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PVD28444.1 - 5.6e-07 29.9 0.0 8.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 PVD28444.1 - 1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PVD28444.1 - 2.5e-05 24.3 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 PVD28444.1 - 0.00039 19.8 0.0 0.00072 19.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 PVD28444.1 - 0.0023 18.1 0.0 0.0076 16.3 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PVD28444.1 - 0.0038 17.6 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 PVD28444.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 PVD28444.1 - 0.023 15.3 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 PVD28444.1 - 0.046 13.9 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PVD28444.1 - 0.049 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PVD28444.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PVD28444.1 - 0.063 12.9 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 PVD28444.1 - 0.15 11.7 0.1 0.35 10.4 0.1 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 PVD28446.1 - 4.2e-31 108.2 0.0 4.9e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PVD28446.1 - 0.00062 20.0 0.0 0.001 19.3 0.0 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 PVD28446.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PVD28446.1 - 0.03 14.3 0.2 0.099 12.6 0.0 1.8 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Kinesin PF00225.23 PVD28447.1 - 1.4e-81 274.1 0.0 4e-80 269.3 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD28447.1 - 4.1e-36 124.2 0.0 8.4e-36 123.1 0.0 1.5 1 1 0 1 1 1 1 Microtubule binding THOC7 PF05615.13 PVD28447.1 - 0.002 18.4 1.0 0.0037 17.5 1.0 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 YabA PF06156.13 PVD28447.1 - 0.044 14.4 0.2 12 6.6 0.7 3.3 2 1 0 2 2 2 0 Initiation control protein YabA T2SSE PF00437.20 PVD28447.1 - 0.07 12.2 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ala_racemase_N PF01168.20 PVD28448.1 - 9.5e-13 48.3 0.1 1.2e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF871 PF05913.11 PVD28448.1 - 0.0032 16.7 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) T4_neck-protein PF11649.8 PVD28448.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Virus neck protein DHHC PF01529.20 PVD28449.1 - 4.9e-35 120.5 12.6 4.9e-35 120.5 12.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Fer4_10 PF13237.6 PVD28449.1 - 0.039 14.1 0.8 0.15 12.2 0.8 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain COQ7 PF03232.13 PVD28449.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF1358 PF07096.11 PVD28450.1 - 1e-34 119.0 0.1 1.2e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Lectin_C PF00059.21 PVD28451.1 - 1.1e-16 61.5 0.1 2.8e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Lectin C-type domain DUF1664 PF07889.12 PVD28451.1 - 0.041 13.9 12.4 0.49 10.4 0.3 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) KxDL PF10241.9 PVD28451.1 - 0.094 13.0 2.2 0.66 10.3 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein Fib_alpha PF08702.10 PVD28451.1 - 0.15 12.2 13.2 4.8 7.4 7.0 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 PVD28451.1 - 0.22 11.8 12.1 5.7 7.3 0.7 5.1 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 PVD28451.1 - 0.41 9.2 2.4 0.64 8.5 1.3 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 PVD28451.1 - 0.81 7.5 5.5 0.52 8.2 3.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Plk4_PB2 PF18409.1 PVD28451.1 - 1.5 9.5 4.0 16 6.2 0.9 3.1 1 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 DUF489 PF04356.12 PVD28451.1 - 3.4 7.7 6.4 5.2 7.0 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF1640 PF07798.11 PVD28451.1 - 8.3 6.4 11.1 4.2 7.4 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Neur_chan_LBD PF02931.23 PVD28452.1 - 1.5e-53 181.5 2.0 1.9e-53 181.1 2.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD28452.1 - 2.3e-10 40.9 1.1 9.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region zf-RING_UBOX PF13445.6 PVD28454.1 - 8.6e-07 28.9 3.5 8.6e-07 28.9 3.5 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD28454.1 - 0.00011 22.0 3.4 0.00011 22.0 3.4 4.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD28454.1 - 0.00014 21.9 12.0 0.00014 21.9 12.0 4.2 6 0 0 6 6 6 2 B-box zinc finger zf-RING_5 PF14634.6 PVD28454.1 - 0.00014 21.7 3.0 0.00014 21.7 3.0 4.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD28454.1 - 0.00018 21.7 1.6 0.00018 21.7 1.6 4.5 4 0 0 4 4 4 1 Ring finger domain TRAP_alpha PF03896.16 PVD28454.1 - 0.00076 18.8 0.6 0.00076 18.8 0.6 1.8 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit zf-C3HC4_2 PF13923.6 PVD28454.1 - 0.0037 17.1 2.1 0.0037 17.1 2.1 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Mrr_cat PF04471.12 PVD28454.1 - 0.0084 16.1 2.5 0.017 15.2 1.5 2.1 2 1 0 2 2 2 1 Restriction endonuclease RNA_pol_Rpb6 PF01192.22 PVD28454.1 - 0.12 12.3 1.1 2.4 8.1 0.4 2.7 2 1 0 2 2 2 0 RNA polymerase Rpb6 DUF948 PF06103.11 PVD28454.1 - 0.72 10.2 3.2 9.7 6.5 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) C1q PF00386.21 PVD28455.1 - 2.7e-09 37.3 0.8 8.2e-09 35.8 0.8 1.9 1 1 0 1 1 1 1 C1q domain zf-RING_UBOX PF13445.6 PVD28455.1 - 1.1e-06 28.5 3.6 1.1e-06 28.5 3.6 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD28455.1 - 5e-05 23.1 1.8 5e-05 23.1 1.8 3.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD28455.1 - 0.00018 21.6 12.0 0.00018 21.6 12.0 3.9 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 PVD28455.1 - 0.0002 21.3 3.0 0.0002 21.3 3.0 4.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD28455.1 - 0.00023 21.5 1.6 0.00023 21.5 1.6 4.5 4 0 0 4 4 4 1 Ring finger domain TRAP_alpha PF03896.16 PVD28455.1 - 0.0009 18.5 0.9 0.0009 18.5 0.9 1.8 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit zf-C3HC4_2 PF13923.6 PVD28455.1 - 0.0046 16.8 2.1 0.0046 16.8 2.1 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Mrr_cat PF04471.12 PVD28455.1 - 0.21 11.6 1.4 0.57 10.2 0.8 2.0 2 1 0 2 2 2 0 Restriction endonuclease C1q PF00386.21 PVD28456.1 - 9.4e-19 67.9 5.5 1.8e-09 37.8 0.3 2.6 2 0 0 2 2 2 2 C1q domain zf-RING_UBOX PF13445.6 PVD28456.1 - 1.1e-11 44.6 10.7 3.3e-07 30.2 0.8 4.9 5 0 0 5 5 3 2 RING-type zinc-finger zf-B_box PF00643.24 PVD28456.1 - 5.6e-08 32.8 78.1 0.00063 19.8 11.2 7.0 7 0 0 7 7 7 4 B-box zinc finger zf-RING_5 PF14634.6 PVD28456.1 - 1.2e-06 28.4 16.8 0.00012 22.0 5.7 7.5 5 3 0 5 5 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD28456.1 - 1.9e-06 27.6 10.6 0.00018 21.3 2.1 6.6 8 0 0 8 8 6 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28456.1 - 3.7e-06 27.2 9.7 0.0002 21.6 1.9 8.2 8 0 0 8 8 6 2 Ring finger domain Mrr_cat PF04471.12 PVD28456.1 - 4e-06 26.8 3.7 0.056 13.5 0.3 3.3 2 0 0 2 2 2 2 Restriction endonuclease zf-C3HC4_2 PF13923.6 PVD28456.1 - 0.0013 18.5 11.4 0.0048 16.7 2.1 6.8 8 0 0 8 8 6 2 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb6 PF01192.22 PVD28456.1 - 0.0018 18.1 6.4 0.69 9.9 0.2 4.5 4 0 0 4 4 4 1 RNA polymerase Rpb6 PA14 PF07691.12 PVD28456.1 - 0.0037 17.1 0.2 3.1 7.6 0.0 2.6 2 0 0 2 2 2 2 PA14 domain DUF1444 PF07285.11 PVD28456.1 - 0.05 13.2 3.1 2.2 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1444) TRAP_alpha PF03896.16 PVD28456.1 - 0.096 11.9 6.9 0.014 14.6 1.2 2.5 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Macro_2 PF14519.6 PVD28456.1 - 0.11 11.8 0.3 11 5.2 0.1 2.3 2 0 0 2 2 2 0 Macro-like domain Ins134_P3_kin PF05770.11 PVD28456.1 - 0.12 11.9 2.7 11 5.4 0.1 2.9 3 0 0 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Potassium_chann PF11404.8 PVD28456.1 - 0.17 11.7 1.9 21 5.0 0.1 3.0 2 0 0 2 2 2 0 Potassium voltage-gated channel RNA_pol_Rpc4 PF05132.14 PVD28456.1 - 0.51 10.8 4.7 1.8 9.0 2.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_27 PF13514.6 PVD28456.1 - 1.7 8.2 10.6 1.1 8.7 0.6 2.9 3 0 0 3 3 3 0 AAA domain CobD_Cbib PF03186.13 PVD28456.1 - 6.5 5.9 8.9 12 5.0 1.6 2.5 2 0 0 2 2 2 0 CobD/Cbib protein zf-B_box PF00643.24 PVD28457.1 - 1.1e-05 25.5 28.9 0.00037 20.6 11.3 3.2 3 0 0 3 3 3 2 B-box zinc finger C1q PF00386.21 PVD28457.1 - 0.00045 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 C1q domain RNA_pol_Rpb6 PF01192.22 PVD28457.1 - 0.0066 16.3 1.1 0.38 10.7 0.3 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 Mrr_cat PF04471.12 PVD28457.1 - 0.019 14.9 3.6 0.027 14.5 2.2 2.0 2 1 0 2 2 2 0 Restriction endonuclease E7 PF00527.18 PVD28457.1 - 0.023 14.9 1.9 0.023 14.9 1.9 3.4 4 0 0 4 4 4 0 E7 protein, Early protein AAA_27 PF13514.6 PVD28457.1 - 1.2 8.6 4.7 0.36 10.4 0.6 1.9 2 0 0 2 2 2 0 AAA domain IBR PF01485.21 PVD28457.1 - 1.5 9.1 23.8 1.4 9.2 5.7 3.2 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain HLH PF00010.26 PVD28458.1 - 1.2e-12 47.5 4.8 2e-12 46.9 4.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.16 PVD28458.1 - 8e-10 39.8 0.3 8e-10 39.8 0.3 3.3 1 1 0 2 2 2 1 Myogenic Basic domain Mem_trans PF03547.18 PVD28458.1 - 0.024 13.0 0.8 0.029 12.8 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.9 PVD28458.1 - 0.04 12.5 8.7 0.048 12.2 8.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 PVD28458.1 - 0.46 9.3 7.7 0.56 9.0 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SelP_N PF04592.14 PVD28458.1 - 5.9 6.2 18.7 9.7 5.5 18.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 PVD28458.1 - 10 4.8 8.9 14 4.3 8.9 1.1 1 0 0 1 1 1 0 Presenilin 7TM_GPCR_Srx PF10328.9 PVD28459.1 - 0.00026 20.7 13.8 0.00037 20.2 13.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TctB PF07331.11 PVD28459.1 - 0.74 10.1 4.9 4.7 7.5 2.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF5408 PF17402.2 PVD28459.1 - 1.3 8.9 5.7 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5408) APH PF01636.23 PVD28463.1 - 4.5e-18 66.0 0.0 1.4e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family TPR_12 PF13424.6 PVD28464.1 - 1.9e-25 88.9 12.7 3e-11 43.5 0.1 5.5 2 2 3 6 6 6 6 Tetratricopeptide repeat Rapsyn_N PF10579.9 PVD28464.1 - 8.3e-21 73.9 0.1 1.1e-16 60.6 0.0 3.3 3 0 0 3 3 3 2 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.6 PVD28464.1 - 1.4e-16 59.2 8.6 0.001 18.9 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD28464.1 - 1.7e-16 59.2 12.5 0.0012 18.6 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD28464.1 - 2.1e-15 55.5 13.7 0.29 11.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD28464.1 - 1.9e-11 43.9 8.0 6.2e-06 25.8 0.1 2.9 1 1 1 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 PVD28464.1 - 6.4e-09 35.3 6.6 0.19 12.0 0.0 5.5 7 0 0 7 7 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28464.1 - 1.2e-07 32.1 7.5 0.0053 17.2 0.0 5.7 4 3 2 6 6 6 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 PVD28464.1 - 1.2e-06 28.7 3.2 3.8e-06 27.1 3.2 2.0 1 0 0 1 1 1 1 Ring finger domain TPR_10 PF13374.6 PVD28464.1 - 5.4e-06 26.1 10.3 0.082 12.8 0.0 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat SNAP PF14938.6 PVD28464.1 - 8.2e-05 22.2 1.2 0.13 11.7 0.0 2.3 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 PVD28464.1 - 9.3e-05 22.4 0.1 0.9 9.7 0.0 3.0 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat zf-RING_5 PF14634.6 PVD28464.1 - 0.00011 22.1 2.1 0.0003 20.7 2.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD28464.1 - 0.00012 21.9 1.7 0.00027 20.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD28464.1 - 0.0017 18.1 1.7 0.005 16.7 1.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3856 PF12968.7 PVD28464.1 - 0.0027 17.8 2.5 2.7 8.0 0.0 4.5 2 1 3 5 5 5 1 Domain of Unknown Function (DUF3856) zf-RING_UBOX PF13445.6 PVD28464.1 - 0.0031 17.5 2.3 0.0096 15.9 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 PVD28464.1 - 0.0031 17.3 1.3 0.015 15.1 1.3 2.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TPR_11 PF13414.6 PVD28464.1 - 0.011 15.4 3.7 75 3.1 0.0 5.9 7 0 0 7 7 7 0 TPR repeat TPR_16 PF13432.6 PVD28464.1 - 0.02 15.5 13.1 2.1 9.0 0.3 5.5 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 PVD28464.1 - 0.031 13.5 0.7 2.5 7.2 0.0 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD28464.1 - 0.042 14.7 15.6 8.4 7.5 0.0 7.5 5 2 4 9 9 9 0 Tetratricopeptide repeat DUF4807 PF16065.5 PVD28464.1 - 0.044 13.4 5.4 0.1 12.3 0.1 3.7 4 1 2 6 6 6 0 Domain of unknown function (DUF4807) ComR_TPR PF18710.1 PVD28464.1 - 0.081 12.5 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 ComR tetratricopeptide SAM_2 PF07647.17 PVD28466.1 - 9.5e-14 51.3 0.0 1.9e-07 31.1 0.0 2.7 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD28466.1 - 9.9e-13 48.3 0.0 2.1e-06 28.0 0.0 3.1 2 1 1 3 3 3 2 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 PVD28466.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SAM_2 PF07647.17 PVD28467.1 - 3.9e-13 49.3 0.0 9.1e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD28467.1 - 1.1e-12 48.2 0.0 3e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 PVD28467.1 - 0.034 14.1 1.5 0.084 12.9 0.1 2.2 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) TFIIE_alpha PF02002.17 PVD28468.1 - 8.3e-23 80.2 3.4 1.7e-22 79.2 3.4 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 PVD28468.1 - 8.1e-18 64.5 2.5 8.1e-18 64.5 2.5 2.1 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 PVD28468.1 - 9.6e-07 28.2 0.4 2e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding PyrI_C PF02748.15 PVD28468.1 - 0.06 13.3 2.5 3.3 7.7 0.3 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RNase_H2-Ydr279 PF09468.10 PVD28468.1 - 0.11 12.7 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF5635 PF18685.1 PVD28468.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Zn-ribbon_8 PF09723.10 PVD28468.1 - 0.16 12.1 1.0 0.46 10.6 1.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain C1_2 PF03107.16 PVD28468.1 - 0.66 10.3 2.4 3.2 8.2 2.6 1.9 1 1 1 2 2 2 0 C1 domain Ras PF00071.22 PVD28469.1 - 7.5e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD28469.1 - 3.3e-20 72.5 0.0 2.3e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28469.1 - 4e-11 42.7 0.0 1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD28469.1 - 2.2e-06 27.2 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD28469.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD28469.1 - 0.0038 17.8 0.2 0.0085 16.6 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PVD28469.1 - 0.0063 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PVD28469.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PVD28469.1 - 0.017 15.1 0.1 0.12 12.3 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 PVD28469.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 PVD28469.1 - 0.025 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain SRPRB PF09439.10 PVD28469.1 - 0.032 13.7 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PVD28469.1 - 0.045 13.5 0.0 4.5 7.0 0.0 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 PVD28469.1 - 0.056 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 PVD28469.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 PVD28469.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD28469.1 - 0.17 12.1 0.1 0.49 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain BIR PF00653.21 PVD28470.1 - 3.3e-22 78.9 0.6 3.7e-15 56.3 0.3 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 PVD28470.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 C3HC zinc finger-like AAA_12 PF13087.6 PVD28471.1 - 6.9e-53 179.2 0.0 6.9e-53 179.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 PVD28471.1 - 7.4e-53 180.0 1.0 7.4e-53 180.0 1.0 6.2 5 3 0 6 6 6 1 AAA domain AAA_19 PF13245.6 PVD28471.1 - 3.8e-09 37.0 0.2 1.1e-07 32.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD28471.1 - 4.8e-09 36.2 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 PVD28471.1 - 0.00078 19.3 0.3 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 PVD28471.1 - 0.004 17.2 4.3 0.016 15.2 0.0 4.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 PVD28471.1 - 0.046 13.5 0.0 0.046 13.5 0.0 5.7 7 0 0 7 7 7 0 Viral (Superfamily 1) RNA helicase zf-H2C2_5 PF13909.6 PVD28471.1 - 0.65 9.8 6.9 8.9 6.2 2.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PAE PF03283.13 PVD28472.1 - 2.3e-35 122.4 0.0 2.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase GATase_2 PF00310.21 PVD28473.1 - 1.1e-153 511.9 0.0 2e-153 511.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 PVD28473.1 - 5e-152 506.3 0.0 5e-152 506.3 0.0 2.2 3 0 0 3 3 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 PVD28473.1 - 5.4e-111 370.6 0.0 1.3e-108 362.8 0.0 2.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 PVD28473.1 - 2.4e-79 265.4 2.2 2.5e-79 265.3 0.9 1.7 2 0 0 2 2 2 1 GXGXG motif Pyr_redox_2 PF07992.14 PVD28473.1 - 2.2e-27 96.1 0.1 2.5e-26 92.6 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 PVD28473.1 - 8.3e-21 73.9 0.0 1.9e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 PVD28473.1 - 5.6e-10 39.3 0.0 3.1e-08 33.7 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PVD28473.1 - 9.1e-09 35.0 0.1 0.00036 19.9 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD28473.1 - 1.3e-07 32.0 1.8 0.001 19.6 0.2 3.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 PVD28473.1 - 1.4e-06 27.9 2.7 8.4e-06 25.3 0.2 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 PVD28473.1 - 3.4e-06 26.9 0.0 0.00021 21.0 0.1 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD28473.1 - 3.2e-05 23.2 2.9 0.00051 19.2 0.2 3.2 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 PVD28473.1 - 5.4e-05 22.1 0.1 5.4e-05 22.1 0.1 2.9 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 PVD28473.1 - 8.5e-05 22.1 0.2 8.5e-05 22.1 0.2 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 PVD28473.1 - 0.00066 18.9 1.6 0.13 11.3 0.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 PVD28473.1 - 0.0014 18.0 1.8 0.0064 15.8 0.1 2.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 PVD28473.1 - 0.0015 17.7 0.2 1.4 7.9 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 PVD28473.1 - 0.0022 18.4 0.0 3.3 8.2 0.2 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PVD28473.1 - 0.0064 15.8 1.7 0.0078 15.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 PVD28473.1 - 0.0065 15.8 0.0 0.73 9.1 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 PVD28473.1 - 0.01 14.3 0.0 0.48 8.8 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 PVD28473.1 - 0.011 14.7 0.4 0.079 12.0 0.2 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase ApbA PF02558.16 PVD28473.1 - 0.017 14.8 0.2 0.043 13.5 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PTS_EIIA_1 PF00358.20 PVD28473.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NAD_Gly3P_dh_N PF01210.23 PVD28473.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 PVD28473.1 - 0.21 11.6 0.4 2.1 8.3 0.1 2.9 3 0 0 3 3 2 0 FAD-NAD(P)-binding Adaptin_N PF01602.20 PVD28475.1 - 7.9e-64 216.1 9.2 9.4e-64 215.8 9.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PVD28475.1 - 2.4e-32 112.2 7.7 4.8e-30 104.7 0.3 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD28475.1 - 8.8e-11 42.1 0.4 8.4e-05 22.9 0.2 4.7 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 PVD28475.1 - 8.8e-06 25.6 7.9 0.89 10.0 0.1 6.9 8 0 0 8 8 8 2 HEAT repeat RTP1_C1 PF10363.9 PVD28475.1 - 0.0055 16.9 0.6 0.75 10.0 0.0 3.7 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 PVD28475.1 - 0.025 14.3 0.0 0.34 10.6 0.0 2.7 3 1 1 4 4 4 0 DNA alkylation repair enzyme HEAT_EZ PF13513.6 PVD28475.1 - 0.03 14.8 1.3 2.6 8.7 0.2 4.4 5 1 1 6 6 6 0 HEAT-like repeat Nipped-B_C PF12830.7 PVD28475.1 - 0.04 13.9 1.6 0.23 11.4 0.4 2.5 2 2 0 2 2 2 0 Sister chromatid cohesion C-terminus CLASP_N PF12348.8 PVD28475.1 - 0.12 11.9 1.1 12 5.4 0.0 3.3 3 1 0 3 3 3 0 CLASP N terminal RHD_dimer PF16179.5 PVD28476.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Rel homology dimerisation domain NST1 PF13945.6 PVD28477.1 - 0.00026 21.1 14.7 0.00034 20.8 14.7 1.1 1 0 0 1 1 1 1 Salt tolerance down-regulator Myc_target_1 PF15179.6 PVD28477.1 - 0.0049 16.8 0.6 0.0067 16.3 0.6 1.2 1 0 0 1 1 1 1 Myc target protein 1 RPOL_N PF14700.6 PVD28477.1 - 0.0075 15.7 0.7 0.0087 15.5 0.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF1644 PF07800.12 PVD28477.1 - 0.026 14.6 2.5 0.036 14.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DUF1754 PF08555.10 PVD28477.1 - 0.038 14.8 11.3 0.055 14.3 11.3 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Menin PF05053.13 PVD28477.1 - 0.044 12.2 6.3 0.05 12.0 6.3 1.0 1 0 0 1 1 1 0 Menin Corazonin PF17308.2 PVD28477.1 - 0.17 12.3 10.0 0.27 11.6 10.0 1.2 1 0 0 1 1 1 0 Pro-corazonin TUSC2 PF15000.6 PVD28477.1 - 0.27 11.5 3.7 0.43 10.9 3.7 1.2 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Ureide_permease PF07168.11 PVD28477.1 - 0.47 9.2 1.8 0.55 8.9 1.8 1.1 1 0 0 1 1 1 0 Ureide permease DUF3464 PF11947.8 PVD28477.1 - 0.62 9.8 4.3 0.9 9.3 4.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Methyltransf_12 PF08242.12 PVD28477.1 - 0.69 10.7 2.6 1.1 10.0 2.6 1.4 1 0 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 PVD28477.1 - 0.95 8.2 4.7 1.1 7.9 4.7 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 PVD28477.1 - 1.3 7.8 4.4 1.5 7.6 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HDA2-3 PF11496.8 PVD28477.1 - 1.3 8.1 8.0 1.7 7.7 8.0 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Sec62 PF03839.16 PVD28477.1 - 1.8 8.0 5.3 2.3 7.7 5.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 PVD28477.1 - 2 8.4 5.2 2.8 8.0 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal O-antigen_lig PF13425.6 PVD28477.1 - 2.1 7.1 2.7 2.5 6.8 2.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4834 PF16118.5 PVD28477.1 - 2.5 9.1 10.1 4 8.5 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PAS PF00989.25 PVD28478.1 - 1.4e-11 44.3 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 PVD28478.1 - 2.9e-05 24.3 0.0 6.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 PVD28478.1 - 0.00016 21.9 0.1 0.00034 20.8 0.1 1.6 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 PVD28478.1 - 0.063 13.5 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 PVD28479.1 - 1.1e-05 25.7 0.1 2.7e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 PVD28479.1 - 0.053 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain MdoG PF04349.12 PVD28482.1 - 0.066 12.1 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Insulin PF00049.18 PVD28483.1 - 1.1e-07 32.7 2.6 2e-07 31.9 2.6 1.4 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Nop14 PF04147.12 PVD28485.1 - 0.14 10.3 8.1 0.12 10.6 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PVD28485.1 - 0.94 7.5 21.2 0.87 7.6 21.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 PVD28485.1 - 4.6 6.3 29.8 4.7 6.2 29.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 PVD28485.1 - 5.1 5.3 11.6 4.6 5.4 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 PVD28485.1 - 6.2 5.0 6.1 5.6 5.2 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PapD-like PF14874.6 PVD28486.1 - 1.3e-06 28.5 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF5348 PF17295.2 PVD28486.1 - 0.17 11.8 0.1 0.39 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) ADH_zinc_N PF00107.26 PVD28487.1 - 5.2e-17 62.1 0.0 8.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD28487.1 - 1.2e-08 36.0 0.0 2.9e-07 31.6 0.0 2.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD28487.1 - 2.1e-08 34.0 0.0 6.5e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.6 PVD28487.1 - 0.00098 19.6 0.0 0.1 13.1 0.0 2.7 1 1 1 2 2 2 2 CoA binding domain CCSAP PF15748.5 PVD28488.1 - 0.12 12.5 21.9 0.16 12.2 21.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Nop14 PF04147.12 PVD28488.1 - 4.6 5.3 24.2 5.8 5.0 24.2 1.2 1 0 0 1 1 1 0 Nop14-like family PA26 PF04636.13 PVD28488.1 - 4.7 6.0 10.7 5.7 5.7 10.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Bromodomain PF00439.25 PVD28489.1 - 3.6e-37 126.3 0.1 3.3e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 PVD28489.1 - 4.2e-37 125.5 16.7 7.6e-06 26.6 0.0 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28489.1 - 3e-14 53.1 0.3 4.3e-05 23.7 0.2 5.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD28489.1 - 0.016 14.2 0.2 3.4 6.6 0.0 3.6 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Auxin_resp PF06507.13 PVD28489.1 - 0.057 13.7 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Auxin response factor Prenyltransf PF01255.19 PVD28490.1 - 2.3e-73 246.5 0.1 2.9e-73 246.1 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase BCDHK_Adom3 PF10436.9 PVD28490.1 - 0.054 13.3 0.6 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Tmemb_161AB PF10268.9 PVD28491.1 - 1.4e-178 594.4 15.8 1.7e-178 594.1 15.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB DUF4492 PF14899.6 PVD28491.1 - 0.018 15.0 0.6 0.071 13.0 0.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) HD_4 PF13328.6 PVD28492.1 - 0.0039 16.9 0.1 0.024 14.4 0.1 2.2 2 0 0 2 2 2 1 HD domain DNA_alkylation PF08713.11 PVD28492.1 - 0.13 11.9 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme EF-hand_6 PF13405.6 PVD28493.1 - 2.7e-06 26.8 1.3 0.0018 18.0 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD28493.1 - 4.3e-06 27.1 0.3 0.026 15.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD28493.1 - 0.00024 20.5 1.0 0.0072 15.8 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 PVD28493.1 - 0.019 14.5 0.1 0.019 14.5 0.1 2.2 2 0 0 2 2 2 0 EF hand Galactosyl_T PF01762.21 PVD28494.1 - 1.2e-45 155.8 0.0 1.4e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD28494.1 - 3.6e-05 23.3 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fringe-like UEV PF05743.13 PVD28495.1 - 2.6e-79 262.9 1.9 3e-40 136.9 0.1 2.5 2 0 0 2 2 2 2 UEV domain Proteasome PF00227.26 PVD28495.1 - 5.3e-51 172.8 0.0 1.1e-50 171.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit Vps23_core PF09454.10 PVD28495.1 - 1e-27 95.9 1.1 1e-27 95.9 1.1 2.5 2 0 0 2 2 2 1 Vps23 core domain Proteasome_A_N PF10584.9 PVD28495.1 - 5.6e-12 45.1 0.0 1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UQ_con PF00179.26 PVD28495.1 - 4.8e-07 29.5 1.9 0.0024 17.5 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme FOXP-CC PF16159.5 PVD28495.1 - 0.014 16.0 1.0 0.042 14.5 1.0 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain FapA PF03961.13 PVD28495.1 - 0.11 11.1 4.2 0.087 11.4 2.0 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A TBD PF12845.7 PVD28495.1 - 1.2 9.0 4.6 0.89 9.5 0.2 2.5 2 0 0 2 2 2 0 TBD domain Spc24 PF08286.11 PVD28495.1 - 5.6 7.3 8.3 0.74 10.1 3.7 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Biopterin_H PF00351.21 PVD28496.1 - 2.9e-178 592.0 0.0 3.6e-178 591.6 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 PVD28496.1 - 3.3e-07 30.0 0.0 1.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 ACT domain HS1_rep PF02218.15 PVD28497.1 - 1.4e-121 396.4 78.1 1.5e-21 76.4 5.9 7.6 7 0 0 7 7 7 7 Repeat in HS1/Cortactin SH3_9 PF14604.6 PVD28497.1 - 5.3e-19 67.8 0.1 1.1e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD28497.1 - 1.2e-16 60.1 1.8 1.3e-16 59.9 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD28497.1 - 1e-11 44.3 0.0 2.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 PVD28497.1 - 5.1e-08 33.3 7.8 3.6 8.0 0.0 7.0 1 1 6 7 7 7 4 TMEM210 family SPESP1 PF15754.5 PVD28497.1 - 0.00069 18.9 3.6 0.0013 17.9 3.6 1.4 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 His_Phos_1 PF00300.22 PVD28498.1 - 1e-25 90.6 0.7 1.8e-22 80.0 0.1 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) K1377 PF15352.6 PVD28500.1 - 0.0016 16.8 0.0 0.0016 16.8 0.0 7.4 4 2 2 7 7 7 4 Susceptibility to monomelic amyotrophy HECT PF00632.25 PVD28501.1 - 4.3e-87 292.4 0.0 7.1e-87 291.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 PVD28501.1 - 1.5e-38 131.3 12.2 2.2e-16 60.2 1.5 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD28501.1 - 3e-33 113.7 12.4 6.5e-15 55.3 0.6 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD28501.1 - 1.4e-29 98.8 3.8 5.3e-06 26.4 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 PVD28501.1 - 1.9e-28 98.2 6.5 5.6e-12 45.6 0.1 5.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD28501.1 - 2.6e-24 84.6 7.5 2.1e-06 27.9 0.6 6.7 7 0 0 7 7 7 5 Ankyrin repeat TRAPP PF04051.16 PVD28502.1 - 2.6e-33 114.8 0.0 2.9e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component OSTMP1 PF09777.9 PVD28503.1 - 6.3e-31 107.6 9.2 2.2e-22 79.6 1.5 2.1 1 1 1 2 2 2 2 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.6 PVD28503.1 - 0.016 15.1 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 CECR6/TMEM121 family GATA PF00320.27 PVD28503.1 - 0.065 12.9 0.9 3.6 7.3 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger ADIP PF11559.8 PVD28504.1 - 0.0004 20.5 11.7 0.0004 20.5 11.7 10.6 2 1 10 12 12 12 5 Afadin- and alpha -actinin-Binding zf-C3HC4_3 PF13920.6 PVD28505.1 - 1.3e-06 28.2 4.6 2.5e-06 27.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD28505.1 - 2.8e-05 24.0 5.2 6e-05 22.9 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD28505.1 - 3.5e-05 23.6 5.8 8.1e-05 22.4 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28505.1 - 5e-05 23.1 3.8 0.0001 22.1 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD28505.1 - 5.2e-05 23.5 6.3 0.00013 22.2 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD28505.1 - 0.00042 20.3 4.2 0.0042 17.1 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 PVD28505.1 - 0.00093 18.9 2.8 0.0021 17.8 2.8 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 PVD28505.1 - 0.001 19.1 3.9 0.0024 18.0 3.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD28505.1 - 0.0027 17.5 7.4 0.015 15.2 7.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 PVD28505.1 - 0.1 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Gln-synt_C PF00120.24 PVD28507.1 - 1.8e-57 194.9 0.3 8.4e-55 186.1 0.1 2.1 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PVD28507.1 - 0.04 13.6 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 PVD28508.1 - 1.6e-69 234.5 0.0 2.1e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 PVD28508.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 PVD28508.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Acyl-CoA_dh_C PF12806.7 PVD28508.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Gln-synt_C PF00120.24 PVD28509.1 - 5.9e-67 226.1 0.0 8.8e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PVD28509.1 - 0.0024 17.6 0.0 0.0088 15.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 PVD28509.1 - 0.003 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Actin PF00022.19 PVD28510.1 - 3.6e-80 269.6 0.0 8.5e-79 265.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PVD28510.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein WD40 PF00400.32 PVD28511.1 - 7.8e-22 77.2 8.3 7e-07 29.8 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28511.1 - 0.00062 20.0 0.6 0.02 15.2 0.3 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD28511.1 - 0.0012 17.5 6.2 0.24 10.0 0.1 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Gln-synt_C PF00120.24 PVD28512.1 - 3.2e-69 233.6 0.0 4.7e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 PVD28512.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 PVD28512.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 PVD28513.1 - 1.3e-69 234.8 0.0 1.9e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 PVD28513.1 - 0.0084 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 PVD28513.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 PVD28514.1 - 2e-50 171.8 0.4 3.7e-47 161.0 0.0 2.1 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 PVD28514.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Dmrt1 PF12374.8 PVD28519.1 - 0.11 12.9 1.2 0.19 12.2 0.1 1.9 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Homeodomain PF00046.29 PVD28522.1 - 2.4e-19 68.9 0.5 3.6e-19 68.3 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Pou PF00157.17 PVD28522.1 - 0.0012 18.8 1.6 0.002 18.1 0.7 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain GHMP_kinases_N PF00288.26 PVD28522.1 - 0.0012 19.0 1.0 0.0012 19.0 1.0 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain Homeobox_KN PF05920.11 PVD28522.1 - 0.0095 15.8 0.0 0.0095 15.8 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain DUF521 PF04412.13 PVD28522.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) HTH_18 PF12833.7 PVD28526.1 - 0.06 13.6 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PDCD7 PF16021.5 PVD28527.1 - 0.0046 16.1 7.2 0.0049 16.0 7.2 1.1 1 0 0 1 1 1 1 Programmed cell death protein 7 Tim54 PF11711.8 PVD28527.1 - 0.028 13.2 5.2 0.034 12.9 5.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 PVD28527.1 - 0.047 12.0 10.6 0.05 11.9 10.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PVD28527.1 - 0.083 11.6 4.0 0.097 11.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 PVD28527.1 - 0.093 13.2 5.6 0.12 12.8 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SLC12 PF03522.15 PVD28527.1 - 0.097 11.7 3.1 0.12 11.4 3.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PTPRCAP PF15713.5 PVD28527.1 - 0.15 12.3 10.7 0.21 11.9 10.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 PVD28527.1 - 0.21 11.4 10.1 0.25 11.1 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4569 PF15133.6 PVD28527.1 - 0.23 11.1 3.8 0.27 10.9 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Vfa1 PF08432.10 PVD28527.1 - 0.32 11.3 13.2 0.42 10.9 13.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM163 PF15069.6 PVD28527.1 - 0.5 10.8 6.5 1.2 9.6 6.5 1.6 1 1 0 1 1 1 0 FAM163 family NARP1 PF12569.8 PVD28527.1 - 0.58 9.0 10.7 0.68 8.8 10.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 PVD28527.1 - 0.88 9.6 2.3 0.96 9.5 2.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4484 PF14831.6 PVD28527.1 - 0.92 9.5 6.2 1.6 8.8 6.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Zip PF02535.22 PVD28527.1 - 1.5 8.0 4.0 1.7 7.8 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM119 PF15724.5 PVD28527.1 - 1.6 8.7 5.8 2 8.4 5.8 1.1 1 0 0 1 1 1 0 TMEM119 family Hid1 PF12722.7 PVD28527.1 - 2.2 6.3 4.6 2.4 6.2 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 PVD28527.1 - 3.2 7.5 8.3 3.9 7.2 8.3 1.2 1 0 0 1 1 1 0 Connexin MAP17 PF15807.5 PVD28527.1 - 3.2 8.0 8.7 4.7 7.5 8.7 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RNA_polI_A34 PF08208.11 PVD28527.1 - 3.8 7.6 23.8 5.1 7.1 23.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 VIR_N PF15912.5 PVD28527.1 - 4.1 6.9 8.3 5.1 6.6 8.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal V_ATPase_I PF01496.19 PVD28527.1 - 4.7 5.0 5.6 5 4.9 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TssC PF17541.2 PVD28528.1 - 0.13 11.1 0.1 0.14 11.0 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Utp11 PF03998.13 PVD28532.1 - 1.8e-53 182.0 25.0 1.8e-53 182.0 25.0 2.8 3 0 0 3 3 3 1 Utp11 protein Peptidase_S8 PF00082.22 PVD28532.1 - 1.9e-40 139.0 5.7 2.6e-40 138.5 5.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 PVD28532.1 - 3e-22 78.4 0.0 6.4e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 PVD28532.1 - 1.7e-16 60.8 1.2 1.7e-16 60.8 1.2 2.8 2 0 0 2 2 2 1 Peptidase S8 pro-domain Y_phosphatase PF00102.27 PVD28533.1 - 2.8e-71 239.8 0.0 8.5e-71 238.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD28533.1 - 1.4e-43 147.1 25.0 1.4e-09 38.2 2.0 10.7 10 1 0 10 10 10 7 Fibronectin type III domain DUF2369 PF10179.9 PVD28533.1 - 5e-12 46.0 0.6 0.0029 17.9 0.0 4.9 5 0 0 5 5 5 3 Uncharacterised conserved protein (DUF2369) Tissue_fac PF01108.17 PVD28533.1 - 9.2e-06 25.5 1.2 0.061 13.2 0.0 3.4 2 0 0 2 2 2 2 Tissue factor PTP_tm PF18861.1 PVD28533.1 - 0.00027 21.0 1.4 0.045 13.8 0.4 4.3 3 2 0 3 3 3 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J PTPlike_phytase PF14566.6 PVD28533.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate FAM176 PF14851.6 PVD28533.1 - 0.047 13.4 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 0 FAM176 family DSPc PF00782.20 PVD28533.1 - 0.064 13.1 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Arylsulfotran_N PF17425.2 PVD28533.1 - 0.89 9.6 8.5 1.5 8.9 0.0 4.9 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain Podoplanin PF05808.11 PVD28533.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.9 4 1 0 4 4 4 0 Podoplanin MFS_1 PF07690.16 PVD28534.1 - 1.6e-23 83.2 40.8 9.1e-23 80.7 36.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily 7tm_3 PF00003.22 PVD28536.1 - 1.4e-54 185.3 16.5 1.4e-54 185.3 16.5 1.4 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 PVD28536.1 - 2e-13 50.0 8.5 2e-13 50.0 8.5 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR ANF_receptor PF01094.28 PVD28536.1 - 2.5e-07 30.2 0.0 3.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region HemY_N PF07219.13 PVD28536.1 - 0.54 10.5 1.5 17 5.6 0.0 2.7 2 0 0 2 2 2 0 HemY protein N-terminus SelP_N PF04592.14 PVD28536.1 - 2.6 7.4 19.5 4.6 6.6 19.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ANF_receptor PF01094.28 PVD28537.1 - 1.2e-60 205.5 0.0 1.7e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD28537.1 - 6.7e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein BNIP2 PF12496.8 PVD28539.1 - 0.3 11.5 7.1 0.66 10.4 3.6 2.5 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 BTB_2 PF02214.22 PVD28540.1 - 6.7e-19 68.0 0.0 1.6e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FapA PF03961.13 PVD28540.1 - 0.0065 15.1 2.0 0.0079 14.9 2.0 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A BTB_3 PF16017.5 PVD28540.1 - 0.019 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 PVD28540.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Spectrin PF00435.21 PVD28540.1 - 0.48 10.9 9.8 0.1 13.1 5.9 1.8 2 0 0 2 2 2 0 Spectrin repeat TMPIT PF07851.13 PVD28540.1 - 2.2 7.4 5.1 6.2 6.0 4.8 1.6 1 1 1 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 PVD28540.1 - 4.4 5.1 5.8 6.2 4.6 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sugar_tr PF00083.24 PVD28541.1 - 8.6e-35 120.5 17.7 1.3e-34 119.9 17.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD28541.1 - 1.1e-22 80.5 34.6 2.5e-16 59.6 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCR_6-4kD PF08997.10 PVD28541.1 - 0.035 14.0 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein SLATT_fungal PF18142.1 PVD28541.1 - 9 6.3 7.8 5.9 6.9 3.1 2.8 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Sugar_tr PF00083.24 PVD28542.1 - 1.5e-69 235.1 78.2 4e-33 114.9 15.0 5.2 3 2 2 5 5 5 5 Sugar (and other) transporter MFS_1 PF07690.16 PVD28542.1 - 6.1e-47 160.3 141.8 2.8e-13 49.5 40.7 6.7 3 3 3 6 6 6 6 Major Facilitator Superfamily CENP-B_dimeris PF09026.10 PVD28542.1 - 0.17 12.3 1.3 0.41 11.1 1.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Penaeidin PF05927.11 PVD28542.1 - 0.19 12.5 2.2 94 3.9 0.0 4.9 4 0 0 4 4 4 0 Penaeidin Crl PF07417.12 PVD28542.1 - 1.9 8.6 6.3 3.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Sigma factor-binding transcriptional regulator Crl GlpM PF06942.12 PVD28542.1 - 4.5 7.7 16.4 2.3 8.7 2.0 4.8 4 0 0 4 4 4 0 GlpM protein CLN3 PF02487.17 PVD28542.1 - 4.8 6.1 28.8 0.31 10.0 2.6 4.0 4 0 0 4 4 4 0 CLN3 protein baeRF_family10 PF18854.1 PVD28543.1 - 2.3 8.4 6.7 12 6.1 6.7 2.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 ADH_zinc_N PF00107.26 PVD28544.1 - 3e-20 72.5 0.2 5.2e-20 71.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD28544.1 - 9.8e-16 59.0 0.0 1.7e-15 58.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD28544.1 - 5.1e-09 36.0 0.0 4.3e-08 33.0 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TDH PF03347.13 PVD28544.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin zf-RanBP PF00641.18 PVD28545.1 - 9.5e-07 28.0 2.8 2.5e-06 26.7 2.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HIP1_clath_bdg PF16515.5 PVD28545.1 - 3.3 8.4 9.0 0.88 10.2 5.8 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WD40 PF00400.32 PVD28546.1 - 1.9e-28 98.1 13.6 2e-07 31.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PVD28546.1 - 4e-28 97.5 1.5 4e-27 94.3 0.3 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 PVD28546.1 - 2.6e-05 24.4 2.3 0.012 15.9 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD28546.1 - 0.00011 22.2 0.9 0.014 15.3 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A EF-hand_4 PF12763.7 PVD28547.1 - 3.1e-22 78.5 0.0 2.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PVD28547.1 - 1.1e-05 24.7 0.0 0.0017 17.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD28547.1 - 4.6e-05 23.8 0.0 0.0014 19.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD28547.1 - 0.0016 18.2 0.0 0.6 10.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD28547.1 - 0.017 14.6 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_10 PF14788.6 PVD28547.1 - 0.074 12.9 0.3 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 EF hand Thiolase_N PF00108.23 PVD28548.1 - 4.9e-98 327.6 2.8 7.6e-98 327.0 2.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD28548.1 - 2.1e-12 46.8 0.4 2.7e-11 43.2 0.0 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PVD28548.1 - 1.1e-06 28.5 5.2 2.5e-06 27.3 3.4 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 PVD28548.1 - 0.21 11.4 0.8 10 6.0 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ank_2 PF12796.7 PVD28549.1 - 4.1e-33 113.8 8.0 4.4e-15 56.0 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD28549.1 - 1.6e-30 104.7 7.3 2.4e-09 37.3 0.6 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD28549.1 - 8.3e-28 96.4 7.3 2.7e-07 31.0 0.2 6.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 PVD28549.1 - 1.2e-27 95.1 4.5 0.00021 21.6 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 PVD28549.1 - 4.5e-20 69.6 2.3 0.00048 20.4 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat DUF1664 PF07889.12 PVD28549.1 - 0.12 12.4 1.1 0.33 11.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD28549.1 - 0.26 11.1 6.3 0.55 10.1 6.3 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BTB PF00651.31 PVD28551.1 - 8.9e-22 77.4 0.0 1.7e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD28551.1 - 9.7e-08 32.1 0.0 6e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch SRCR PF00530.18 PVD28552.1 - 6.1e-56 187.1 15.8 2.1e-16 60.3 0.1 5.2 4 1 1 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD28552.1 - 1.7e-16 60.5 2.5 0.00028 21.3 0.1 3.8 3 1 1 4 4 4 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD28552.1 - 2.5e-08 34.4 0.4 0.05 14.1 0.0 3.6 4 0 0 4 4 4 3 Hepsin, SRCR domain Prok-RING_1 PF14446.6 PVD28552.1 - 7.5 6.6 10.6 6.2 6.8 0.1 3.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 ASC PF00858.24 PVD28553.1 - 2.7e-54 184.8 13.5 4.1e-53 180.9 9.3 4.3 2 2 1 3 3 3 2 Amiloride-sensitive sodium channel EphA2_TM PF14575.6 PVD28554.1 - 0.011 16.6 0.3 0.023 15.6 0.3 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD28554.1 - 0.03 14.2 0.3 0.06 13.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.6 PVD28554.1 - 0.03 14.5 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 PVD28554.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SID-1_RNA_chan PF13965.6 PVD28554.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_19 PF13245.6 PVD28555.1 - 0.00043 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD28555.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 PVD28555.1 - 0.047 13.2 0.0 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 PVD28555.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 PVD28555.1 - 0.084 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 PVD28555.1 - 0.089 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.22 PVD28556.1 - 1.2e-19 70.5 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Y_phosphatase PF00102.27 PVD28557.1 - 2.7e-13 50.0 0.1 9.1e-06 25.4 0.2 2.3 1 1 1 2 2 2 2 Protein-tyrosine phosphatase EphA2_TM PF14575.6 PVD28557.1 - 0.0014 19.4 0.0 0.0034 18.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 PVD28557.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E BatA PF07584.11 PVD28557.1 - 0.051 13.9 0.4 0.11 12.9 0.4 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal LPG_synthase_TM PF03706.13 PVD28557.1 - 0.065 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TarH PF02203.15 PVD28557.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Syndecan PF01034.20 PVD28557.1 - 0.35 10.8 1.4 0.62 10.0 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain fn3 PF00041.21 PVD28558.1 - 2.8e-56 187.8 46.4 1.9e-08 34.5 0.1 14.0 11 4 0 11 11 11 9 Fibronectin type III domain Y_phosphatase PF00102.27 PVD28558.1 - 1.9e-35 122.5 0.0 4.9e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2369 PF10179.9 PVD28558.1 - 1.8e-18 66.7 10.0 0.056 13.8 0.0 8.1 8 0 0 8 8 8 5 Uncharacterised conserved protein (DUF2369) RNA_pol_Rpb6 PF01192.22 PVD28558.1 - 1e-11 44.5 0.1 2e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pur_ac_phosph_N PF16656.5 PVD28558.1 - 3.2e-06 27.6 54.6 0.042 14.4 0.1 11.2 10 3 1 11 11 11 4 Purple acid Phosphatase, N-terminal domain PTP_tm PF18861.1 PVD28558.1 - 5.8e-06 26.4 3.4 2.6 8.0 0.0 5.2 6 0 0 6 6 6 3 Transmembrane domain of protein tyrosine phosphatase, receptor type J Tissue_fac PF01108.17 PVD28558.1 - 0.095 12.6 0.1 0.095 12.6 0.1 4.9 6 0 0 6 6 6 0 Tissue factor EphA2_TM PF14575.6 PVD28558.1 - 0.14 13.0 0.0 0.44 11.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LPG_synthase_TM PF03706.13 PVD28558.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region BatA PF07584.11 PVD28558.1 - 0.17 12.3 0.2 0.38 11.1 0.2 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Y_phosphatase PF00102.27 PVD28559.1 - 6e-79 264.9 0.4 1.7e-78 263.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD28559.1 - 3e-17 62.7 23.4 1.8e-09 37.8 5.8 6.8 6 1 0 6 6 6 3 Fibronectin type III domain DSPc PF00782.20 PVD28559.1 - 2.9e-07 30.3 0.2 1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD28559.1 - 0.00069 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Big_10 PF17964.1 PVD28559.1 - 0.0012 18.9 3.7 0.026 14.5 1.0 2.6 2 0 0 2 2 2 1 Bacterial Ig domain PTPlike_phytase PF14566.6 PVD28559.1 - 0.024 14.8 0.0 0.076 13.1 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate YebO PF13974.6 PVD28559.1 - 0.05 13.7 1.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 YebO-like protein SKG6 PF08693.10 PVD28559.1 - 0.24 10.8 2.1 0.65 9.5 2.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 PVD28559.1 - 0.29 10.9 1.4 0.62 9.9 1.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EB PF01683.18 PVD28559.1 - 1.4 9.2 11.3 0.022 15.0 3.5 2.1 2 0 0 2 2 2 0 EB module Y_phosphatase PF00102.27 PVD28560.1 - 4.5e-28 98.4 0.1 2.6e-17 63.2 0.0 2.5 2 1 1 3 3 3 2 Protein-tyrosine phosphatase EphA2_TM PF14575.6 PVD28560.1 - 0.0031 18.4 0.1 0.007 17.2 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1673 PF07895.11 PVD28560.1 - 0.039 13.7 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) ECSCR PF15820.5 PVD28560.1 - 0.12 12.2 1.1 0.3 10.9 0.5 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF3522 PF12036.8 PVD28560.1 - 0.12 12.6 0.8 0.2 11.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Adeno_E3_CR2 PF02439.15 PVD28560.1 - 0.12 12.1 3.4 0.33 10.8 3.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 PVD28560.1 - 0.2 11.7 8.2 0.24 11.5 4.3 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Stevor PF17410.2 PVD28560.1 - 0.36 10.3 3.0 0.59 9.6 3.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FeoB_associated PF12669.7 PVD28560.1 - 5.3 7.5 4.7 13 6.3 4.7 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SKG6 PF08693.10 PVD28560.1 - 5.9 6.4 11.6 12 5.4 11.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 7tm_1 PF00001.21 PVD28561.1 - 2.7e-40 138.4 21.1 3.3e-40 138.1 21.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Exo_endo_phos PF03372.23 PVD28562.1 - 6.2e-12 45.5 0.0 8.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Insulin PF00049.18 PVD28564.1 - 5.5e-09 36.9 1.5 9.2e-09 36.2 1.5 1.4 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family TSP_3 PF02412.18 PVD28565.1 - 0.00073 19.2 5.9 0.31 10.8 0.5 2.6 2 0 0 2 2 2 2 Thrombospondin type 3 repeat Spore-coat_CotD PF11122.8 PVD28565.1 - 3.8 8.4 6.1 17 6.3 0.1 2.7 3 0 0 3 3 3 0 Inner spore coat protein D TMEM52 PF14979.6 PVD28568.1 - 0.01 15.7 0.5 0.024 14.6 0.5 1.6 1 0 0 1 1 1 0 Transmembrane 52 TMIE PF16038.5 PVD28568.1 - 0.018 14.9 0.1 0.042 13.7 0.0 1.7 1 1 0 1 1 1 0 TMIE protein EGF_alliinase PF04863.13 PVD28568.1 - 0.034 14.6 0.4 0.087 13.2 0.4 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain EGF_2 PF07974.13 PVD28568.1 - 8.8 6.8 8.3 1.1 9.7 3.1 2.3 2 0 0 2 2 2 0 EGF-like domain TFIID-18kDa PF02269.16 PVD28570.1 - 1e-24 86.3 0.5 2.1e-24 85.3 0.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Runt PF00853.19 PVD28571.1 - 4.7e-46 155.5 0.1 5.4e-46 155.3 0.1 1.1 1 0 0 1 1 1 1 Runt domain VIR_N PF15912.5 PVD28572.1 - 0.0048 16.5 8.0 0.0082 15.8 8.0 1.4 1 0 0 1 1 1 1 Virilizer, N-terminal AalphaY_MDB PF04611.12 PVD28572.1 - 0.13 12.2 1.7 0.18 11.8 0.2 1.9 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region Amidase PF01425.21 PVD28573.1 - 1.8e-126 422.7 0.0 2.1e-90 303.9 0.0 2.0 2 0 0 2 2 2 2 Amidase Utp14 PF04615.13 PVD28574.1 - 7.9e-118 395.1 61.7 2.6e-63 214.8 36.0 2.3 1 1 1 2 2 2 2 Utp14 protein TTL PF03133.15 PVD28575.1 - 1.5e-76 257.4 0.3 2.7e-76 256.5 0.3 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD28575.1 - 4e-05 23.0 0.1 0.00084 18.7 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD28575.1 - 0.0034 16.7 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2249 PF10006.9 PVD28575.1 - 0.043 13.7 0.8 0.11 12.3 0.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) 7tm_1 PF00001.21 PVD28576.1 - 5.7e-37 127.5 5.8 6.9e-37 127.2 5.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD28576.1 - 1.4e-08 34.4 7.6 1.9e-08 34.0 7.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD28576.1 - 3.1e-07 30.0 4.3 6.1e-07 29.0 4.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 PVD28576.1 - 0.0041 16.9 0.7 0.0041 16.9 0.7 1.7 2 0 0 2 2 2 1 Olfactory receptor DUF1418 PF07214.12 PVD28576.1 - 0.15 11.9 0.6 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SecE PF00584.20 PVD28576.1 - 0.41 10.6 3.3 2 8.4 0.1 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2207 PF09972.9 PVD28576.1 - 4.9 5.8 7.0 2.6 6.7 1.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF908 PF06012.12 PVD28577.1 - 0.0023 17.4 5.6 0.0025 17.3 5.6 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Zip PF02535.22 PVD28577.1 - 0.069 12.4 1.8 0.076 12.2 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 PVD28577.1 - 0.58 9.5 17.9 0.97 8.8 17.9 1.5 1 1 0 1 1 1 0 Selenoprotein P, N terminal region Mucin PF01456.17 PVD28577.1 - 0.68 9.9 32.8 1.1 9.3 32.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 PVD28577.1 - 4.3 5.8 8.0 5.1 5.5 8.0 1.0 1 0 0 1 1 1 0 Macoilin family MGC-24 PF05283.11 PVD28577.1 - 5.2 7.5 17.0 11 6.5 17.0 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1387 PF07139.11 PVD28577.1 - 7.7 6.2 8.4 9.5 5.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) C2 PF00168.30 PVD28579.1 - 4.6e-38 129.7 0.0 6.8e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 PVD28579.1 - 1.6e-05 24.9 0.0 0.014 15.3 0.0 2.7 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 NT-C2 PF10358.9 PVD28579.1 - 0.071 12.8 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 PVD28581.1 - 2.1e-34 117.9 0.0 3.4e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD28581.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain NUC205 PF08168.11 PVD28582.1 - 0.033 13.7 0.3 0.72 9.4 0.1 2.8 1 1 1 2 2 2 0 NUC205 domain HSP20 PF00011.21 PVD28584.1 - 6.2e-18 64.8 0.0 2e-09 37.5 0.0 3.0 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD28584.1 - 0.00035 20.1 0.0 0.0027 17.2 0.0 2.3 2 0 0 2 2 2 1 HSP20-like domain found in ArsA BssB_TutG PF18512.1 PVD28584.1 - 0.089 12.7 4.8 0.062 13.2 1.5 2.5 3 0 0 3 3 3 0 Benzylsuccinate synthase beta subunit ATP-synt_B PF00430.18 PVD28584.1 - 3.6 7.7 6.9 2.1 8.5 3.1 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF1126 PF06565.12 PVD28585.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.7 1 1 0 1 1 1 1 DUF1126 PH-like domain EF-hand_7 PF13499.6 PVD28585.1 - 0.0024 18.3 0.3 0.0024 18.3 0.3 2.6 4 0 0 4 4 4 1 EF-hand domain pair ApoL PF05461.11 PVD28585.1 - 0.04 13.3 0.2 0.062 12.6 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein L EF-hand_6 PF13405.6 PVD28585.1 - 0.58 10.2 3.3 5 7.3 0.0 3.6 5 0 0 5 5 5 0 EF-hand domain eIF3_N PF09440.10 PVD28586.1 - 0.21 12.0 0.7 0.32 11.4 0.7 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain VWC PF00093.18 PVD28590.1 - 1.6e-20 73.2 40.7 3e-07 30.7 5.2 4.2 1 1 3 4 4 4 4 von Willebrand factor type C domain Pacifastin_I PF05375.13 PVD28590.1 - 9e-19 66.9 50.2 3.3e-07 29.9 10.8 4.5 4 0 0 4 4 4 4 Pacifastin inhibitor (LCMII) TILa PF12714.7 PVD28590.1 - 3.8e-14 52.4 42.0 8.9e-06 25.6 6.2 4.1 2 1 2 4 4 4 4 TILa domain Fucose_iso_C PF02952.17 PVD28590.1 - 0.015 15.0 0.4 0.029 14.1 0.4 1.6 1 1 0 1 1 1 0 L-fucose isomerase, C-terminal domain CFC PF09443.10 PVD28590.1 - 4.9 7.1 38.3 1.1 9.2 0.4 4.7 4 0 0 4 4 4 0 Cripto_Frl-1_Cryptic (CFC) 5_nucleotid PF05761.14 PVD28591.1 - 2.7e-61 207.9 0.2 3.8e-61 207.4 0.2 1.2 1 0 0 1 1 1 1 5' nucleotidase family Pacifastin_I PF05375.13 PVD28591.1 - 2.8e-10 39.7 18.4 4e-08 32.8 5.7 2.6 2 0 0 2 2 2 2 Pacifastin inhibitor (LCMII) VWC PF00093.18 PVD28591.1 - 8.8e-08 32.4 12.0 0.00027 21.2 3.8 2.5 1 1 1 2 2 2 2 von Willebrand factor type C domain TILa PF12714.7 PVD28591.1 - 1.7e-06 27.8 14.0 0.00046 20.1 4.5 2.5 2 0 0 2 2 2 2 TILa domain CFC PF09443.10 PVD28591.1 - 0.04 13.8 15.4 0.59 10.0 4.5 2.6 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Antistasin PF02822.14 PVD28591.1 - 5.7 7.7 11.6 3.9 8.2 0.4 3.0 2 0 0 2 2 2 0 Antistasin family Collagen_mid PF15984.5 PVD28592.1 - 3.3e-08 33.5 2.9 6.9e-05 22.7 3.4 3.1 1 1 1 2 2 2 1 Bacterial collagen, middle region DUF948 PF06103.11 PVD28592.1 - 1.7e-05 25.0 7.5 0.0068 16.6 4.0 3.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 PVD28592.1 - 7.4e-05 22.6 0.3 0.011 15.5 0.5 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 PVD28592.1 - 9.8e-05 22.7 12.0 0.15 12.5 0.1 3.1 1 1 2 3 3 3 3 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 PVD28592.1 - 0.00091 19.3 0.3 0.0048 16.9 0.3 2.0 1 1 1 2 2 2 1 Laminin Domain II DUF1664 PF07889.12 PVD28592.1 - 0.0012 18.9 1.8 0.53 10.3 2.9 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PVD28592.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PVD28592.1 - 0.0032 18.0 10.2 60 4.3 10.2 3.5 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.11 PVD28592.1 - 0.0033 17.5 0.0 0.13 12.4 0.4 2.6 1 1 2 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 PVD28592.1 - 0.0079 16.2 0.1 2.3 8.2 0.1 2.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TFR_dimer PF04253.15 PVD28592.1 - 0.011 15.9 0.1 10 6.2 0.0 3.1 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain DUF5082 PF16888.5 PVD28592.1 - 0.017 15.4 1.5 0.062 13.6 1.0 2.2 3 1 1 4 4 2 0 Domain of unknown function (DUF5082) Nup88 PF10168.9 PVD28592.1 - 0.021 12.7 0.0 0.03 12.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore component DegS PF05384.11 PVD28592.1 - 0.029 13.8 2.9 0.05 13.1 2.9 1.3 1 0 0 1 1 1 0 Sensor protein DegS CdvA PF18822.1 PVD28592.1 - 0.038 13.8 0.1 0.24 11.3 0.4 2.1 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Phasin PF05597.11 PVD28592.1 - 0.04 13.9 2.3 0.6 10.1 2.2 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF148 PF02520.17 PVD28592.1 - 0.04 14.0 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF677 PF05055.12 PVD28592.1 - 0.044 12.7 1.4 0.071 12.0 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Cauli_AT PF03233.13 PVD28592.1 - 0.045 13.7 0.2 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 Aphid transmission protein FlaC_arch PF05377.11 PVD28592.1 - 0.056 13.8 3.5 3.3 8.2 2.1 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF445 PF04286.12 PVD28592.1 - 0.062 13.1 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Spc7 PF08317.11 PVD28592.1 - 0.063 12.1 0.2 0.086 11.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec20 PF03908.13 PVD28592.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Sec20 ISG65-75 PF11727.8 PVD28592.1 - 0.12 11.6 0.4 0.26 10.5 0.3 1.7 1 1 1 2 2 2 0 Invariant surface glycoprotein RRF PF01765.19 PVD28592.1 - 0.14 12.1 3.7 0.14 12.1 2.5 1.5 2 0 0 2 2 2 0 Ribosome recycling factor DUF5098 PF17023.5 PVD28592.1 - 0.18 10.8 0.8 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) HisKA PF00512.25 PVD28592.1 - 0.21 11.6 1.6 9.4 6.4 0.3 3.1 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain SPO22 PF08631.10 PVD28592.1 - 0.28 10.6 0.1 0.37 10.2 0.1 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF4455 PF14643.6 PVD28592.1 - 0.35 9.5 1.1 0.44 9.1 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF1542 PF07564.11 PVD28592.1 - 0.41 10.8 4.1 12 6.1 2.0 2.7 2 2 0 2 2 2 0 Domain of Unknown Function (DUF1542) Synaptobrevin PF00957.21 PVD28592.1 - 1.1 9.1 7.3 1.8 8.4 3.8 2.9 2 2 3 5 5 5 0 Synaptobrevin Mce4_CUP1 PF11887.8 PVD28592.1 - 1.2 8.5 4.9 2.1 7.7 0.6 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF615 PF04751.14 PVD28592.1 - 1.4 8.9 2.8 2.6 8.0 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) DUF2992 PF11208.8 PVD28593.1 - 0.011 16.0 13.0 0.011 16.0 13.0 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF2992) DUF948 PF06103.11 PVD28593.1 - 0.84 9.9 19.0 0.55 10.5 5.6 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 PVD28593.1 - 2.5 8.4 38.3 0.24 11.7 7.2 6.3 3 2 2 5 5 5 0 Homeobox associated leucine zipper GAS PF13851.6 PVD28593.1 - 2.6 7.3 61.1 0.39 10.0 17.2 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Methyltransf_32 PF13679.6 PVD28594.1 - 1.7e-26 93.1 3.8 4.6e-25 88.5 3.8 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD28594.1 - 4.1e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD28594.1 - 7.4e-05 23.4 0.0 0.00029 21.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD28594.1 - 0.0039 16.8 0.0 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PVD28594.1 - 0.0039 17.0 0.1 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD28594.1 - 0.018 15.7 0.0 0.066 13.9 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PVD28594.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 PVD28594.1 - 0.065 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 GGDEF_2 PF17853.1 PVD28594.1 - 0.38 11.0 2.5 0.96 9.7 2.5 1.7 1 0 0 1 1 1 0 GGDEF-like domain NERD PF08378.11 PVD28595.1 - 0.0057 17.1 0.0 0.0075 16.7 0.0 1.1 1 0 0 1 1 1 1 Nuclease-related domain Homeodomain PF00046.29 PVD28597.1 - 1.8e-12 46.9 0.9 3.1e-12 46.1 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD28597.1 - 0.0063 16.4 0.4 0.012 15.5 0.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 PVD28597.1 - 0.1 12.1 0.3 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez FAM198 PF15051.6 PVD28598.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAM198 protein LRR_8 PF13855.6 PVD28599.1 - 8.1e-49 163.2 55.0 2.1e-15 56.2 4.9 6.1 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD28599.1 - 4e-28 97.0 40.2 1.5e-07 31.6 1.9 7.9 4 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD28599.1 - 1e-18 67.5 1.3 1.3e-06 28.3 0.0 3.4 1 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD28599.1 - 2e-16 58.0 36.0 0.035 14.6 0.2 11.7 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 PVD28599.1 - 1.4e-06 27.9 38.7 1.8 8.8 0.4 10.3 10 0 0 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.6 PVD28599.1 - 1.2e-05 24.9 15.6 0.029 13.9 1.2 4.0 1 1 3 4 4 4 3 Leucine-rich repeat SAM_3 PF18016.1 PVD28599.1 - 1.3 8.9 3.8 9.2 6.2 0.1 3.6 3 1 1 4 4 4 0 SAM domain (Sterile alpha motif) WW PF00397.26 PVD28600.1 - 1.1e-09 38.1 0.6 2.1e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 WW domain Spc7 PF08317.11 PVD28600.1 - 0.0038 16.2 7.4 0.0038 16.2 7.4 6.2 3 1 3 6 6 6 2 Spc7 kinetochore protein 7tm_6 PF02949.20 PVD28600.1 - 7.7 5.5 5.7 38 3.2 2.2 2.8 2 0 0 2 2 2 0 7tm Odorant receptor Coprogen_oxidas PF01218.18 PVD28601.1 - 4.8e-141 468.7 0.5 5.5e-141 468.5 0.5 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PAE PF03283.13 PVD28602.1 - 6.9e-44 150.4 0.1 2.6e-21 76.1 0.0 2.3 1 1 1 2 2 2 2 Pectinacetylesterase SRP-alpha_N PF04086.13 PVD28602.1 - 3.5 7.5 7.6 5.6 6.8 7.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ras PF00071.22 PVD28606.1 - 0.0038 16.8 0.0 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 Ras family H_lectin PF09458.10 PVD28607.1 - 1.9e-16 60.0 2.2 2.3e-16 59.7 2.2 1.1 1 0 0 1 1 1 1 H-type lectin domain ChitinaseA_N PF08329.10 PVD28607.1 - 0.0055 16.4 0.4 0.0074 15.9 0.4 1.1 1 0 0 1 1 1 1 Chitinase A, N-terminal domain 7tm_1 PF00001.21 PVD28609.1 - 5e-15 55.5 6.4 6.8e-15 55.1 6.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD28609.1 - 5.1e-05 23.0 0.8 6.4e-05 22.7 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD28609.1 - 0.002 17.9 1.5 0.0024 17.7 0.5 1.5 1 1 0 1 1 1 1 Olfactory receptor DUF667 PF05018.13 PVD28610.1 - 0.6 9.8 1.6 22 4.7 0.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF667) RIP PF00161.19 PVD28610.1 - 2.7 7.5 4.3 0.72 9.4 0.1 2.2 3 0 0 3 3 3 0 Ribosome inactivating protein DUF4407 PF14362.6 PVD28610.1 - 5.7 6.2 6.7 13 5.0 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Y_phosphatase PF00102.27 PVD28611.1 - 8.7e-76 254.6 1.8 9.3e-76 254.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD28611.1 - 2.5e-38 130.3 37.6 4.5e-11 42.9 0.1 9.6 9 0 0 9 9 9 8 Fibronectin type III domain DUF3377 PF11857.8 PVD28611.1 - 0.00016 21.5 1.3 0.00051 19.9 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DSPc PF00782.20 PVD28611.1 - 0.00037 20.3 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTP_tm PF18861.1 PVD28611.1 - 0.0069 16.4 6.0 0.053 13.5 6.0 2.5 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J RIFIN PF02009.16 PVD28611.1 - 0.013 15.4 2.4 0.021 14.8 0.0 2.1 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 PVD28611.1 - 0.031 15.1 0.0 0.087 13.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Y_phosphatase3 PF13350.6 PVD28611.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TMEM154 PF15102.6 PVD28611.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 PVD28611.1 - 0.06 13.7 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 PVD28611.1 - 3 8.2 9.2 4.6 7.6 8.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) GFO_IDH_MocA PF01408.22 PVD28612.1 - 0.0023 18.7 2.0 0.029 15.2 0.0 2.9 2 1 1 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4011 PF13195.6 PVD28612.1 - 0.091 12.7 2.9 0.14 12.0 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Dict-STAT-coil PF09267.10 PVD28612.1 - 0.35 11.3 10.0 14 6.1 0.0 3.4 2 1 1 3 3 3 0 Dictyostelium STAT, coiled coil Radical_SAM PF04055.21 PVD28613.1 - 2.2e-31 109.5 0.1 6.1e-31 108.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 PVD28613.1 - 3.1e-22 78.4 0.0 5.9e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 PVD28613.1 - 5.7e-11 42.3 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Sua5_yciO_yrdC PF01300.18 PVD28614.1 - 1.8e-37 128.5 0.0 2.5e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Pkinase PF00069.25 PVD28615.1 - 8.8e-61 205.6 0.1 6e-60 202.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD28615.1 - 3.3e-35 121.6 0.0 7.1e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD28615.1 - 7.6e-08 32.0 0.0 1.8e-07 30.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PVD28615.1 - 0.0046 16.3 0.1 0.0087 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GMC_oxred_C PF05199.13 PVD28617.1 - 5.1e-29 101.6 0.7 6.1e-29 101.4 0.7 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF2974 PF11187.8 PVD28618.1 - 0.00052 19.6 0.2 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) FliD_N PF02465.18 PVD28618.1 - 0.21 12.3 1.3 4.5 8.0 0.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Matrilin_ccoil PF10393.9 PVD28618.1 - 0.27 11.1 2.8 0.55 10.1 0.4 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DASH_Duo1 PF08651.10 PVD28618.1 - 0.58 10.0 4.7 8 6.3 0.0 3.0 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF4140 PF13600.6 PVD28618.1 - 0.8 10.2 3.3 7.8 7.0 1.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 PVD28618.1 - 0.88 9.6 5.7 1.7 8.7 1.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 PVD28618.1 - 1 9.7 4.7 8.2 6.8 0.8 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain Matrilin_ccoil PF10393.9 PVD28619.1 - 0.0088 15.9 0.4 0.0088 15.9 0.4 1.6 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin AcylCoA_dehyd_C PF12186.8 PVD28619.1 - 0.095 12.8 0.4 0.18 11.9 0.4 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Flagellin_N PF00669.20 PVD28619.1 - 0.13 12.3 0.3 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region 7tm_1 PF00001.21 PVD28621.1 - 3.1e-40 138.2 20.9 4.2e-40 137.7 20.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LLGL PF08366.13 PVD28623.1 - 1.5e-35 121.7 0.1 5.5e-35 119.9 0.0 2.1 2 0 0 2 2 2 1 LLGL2 Lgl_C PF08596.10 PVD28623.1 - 6.6e-07 28.4 0.1 5.4e-06 25.4 0.0 2.5 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 PVD28623.1 - 6.4e-05 23.2 1.2 4.3 7.7 0.0 5.7 4 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD28623.1 - 0.00013 22.7 9.4 5 8.2 0.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Synaptobrevin PF00957.21 PVD28623.1 - 0.0011 18.7 0.1 0.0011 18.7 0.1 1.8 2 0 0 2 2 2 1 Synaptobrevin DUF2442 PF10387.9 PVD28623.1 - 0.022 15.0 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) CSTF2_hinge PF14327.6 PVD28624.1 - 8.3e-31 106.3 5.7 8.3e-31 106.3 5.7 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 PVD28624.1 - 7.4e-20 70.3 14.1 2.9e-19 68.3 11.3 2.6 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 PVD28624.1 - 9.7e-11 41.3 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma70_r4_2 PF08281.12 PVD28624.1 - 0.22 11.2 0.6 7.6 6.3 0.3 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Glyco_transf_7N PF13733.6 PVD28626.1 - 7.9e-51 171.2 0.0 1.2e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD28626.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4618 PF15397.6 PVD28627.1 - 8.7e-06 25.3 20.2 1.8e-05 24.3 20.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4515 PF14988.6 PVD28627.1 - 0.11 12.3 24.2 0.071 12.9 8.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) P22_AR_N PF10547.9 PVD28627.1 - 0.14 12.5 6.0 0.056 13.8 2.2 2.0 1 1 1 2 2 2 0 P22_AR N-terminal domain DUF4407 PF14362.6 PVD28627.1 - 3.2 7.0 8.9 4.6 6.5 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 PVD28627.1 - 3.7 7.9 18.6 0.92 9.8 9.7 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-L PF13092.6 PVD28627.1 - 6.3 7.0 8.3 3.8 7.7 0.1 2.2 1 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 HEPN PF05168.14 PVD28628.1 - 1.9e-17 63.5 0.0 3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 HEPN domain CENP-B_dimeris PF09026.10 PVD28628.1 - 0.051 14.0 0.8 0.051 14.0 0.8 2.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ebola_NP PF05505.12 PVD28628.1 - 0.62 8.3 3.8 0.88 7.8 3.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein HATPase_c_3 PF13589.6 PVD28632.1 - 0.00062 19.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ku_C PF03730.14 PVD28632.1 - 0.33 11.7 2.4 0.98 10.2 2.4 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm zf-C4 PF00105.18 PVD28635.1 - 1.3e-25 89.6 13.6 2.2e-25 88.9 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 PVD28635.1 - 9.3 6.7 14.7 0.18 12.1 3.1 2.8 1 1 2 3 3 3 0 C1 domain Hormone_recep PF00104.30 PVD28636.1 - 7e-24 84.6 2.1 3.1e-23 82.4 2.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LicD PF04991.13 PVD28637.1 - 1.8e-12 47.9 0.0 5.3e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 LicD family SNAD3 PF18749.1 PVD28637.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Snf7 PF03357.21 PVD28638.1 - 2.1e-36 125.1 29.9 3.2e-36 124.5 29.9 1.2 1 0 0 1 1 1 1 Snf7 FliG_N PF14842.6 PVD28638.1 - 0.021 15.3 2.5 0.021 15.3 2.5 2.3 1 1 2 3 3 3 0 FliG N-terminal domain hDGE_amylase PF14701.6 PVD28638.1 - 1.5 7.8 9.6 2.1 7.3 9.6 1.4 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain NifQ PF04891.12 PVD28638.1 - 4.9 7.5 7.5 0.64 10.4 0.9 2.0 2 0 0 2 2 2 0 NifQ Ras PF00071.22 PVD28639.1 - 4.9e-42 143.3 0.0 1.2e-41 142.1 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD28639.1 - 1.9e-18 66.8 0.0 4.3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28639.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD28639.1 - 0.0097 16.0 0.1 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 PVD28639.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 PVD28639.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD28639.1 - 0.04 13.5 0.0 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PVD28639.1 - 0.068 12.9 0.1 3.2 7.5 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 PVD28639.1 - 0.11 11.6 0.0 7.5 5.6 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Ribosomal_L24e PF01246.20 PVD28640.1 - 1e-30 105.7 0.9 1e-30 105.7 0.9 2.3 2 1 1 3 3 3 1 Ribosomal protein L24e Band_3_cyto PF07565.13 PVD28640.1 - 1.4 8.7 5.7 1.7 8.4 5.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ISG65-75 PF11727.8 PVD28640.1 - 1.6 7.9 12.4 2.1 7.5 12.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein fn3 PF00041.21 PVD28641.1 - 8.4e-06 26.1 0.1 3e-05 24.3 0.1 2.1 1 0 0 1 1 1 1 Fibronectin type III domain IQ PF00612.27 PVD28641.1 - 2e-05 24.0 1.2 4.7e-05 22.8 1.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4200 PF13863.6 PVD28641.1 - 0.36 11.2 5.9 2 8.8 2.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4061 PF13270.6 PVD28642.1 - 5.9e-10 39.3 0.1 1.3e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) baeRF_family12 PF18856.1 PVD28642.1 - 0.69 10.5 3.6 0.49 11.0 1.4 1.7 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 MFS_1 PF07690.16 PVD28644.1 - 1.5e-18 66.9 21.9 2.1e-16 59.8 6.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Med13_N PF11597.8 PVD28644.1 - 0.049 13.0 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Orai-1 PF07856.12 PVD28644.1 - 0.091 12.4 0.5 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Mediator of CRAC channel activity COX14 PF14880.6 PVD28644.1 - 3.3 7.6 8.4 12 5.8 0.2 4.5 4 1 1 5 5 5 0 Cytochrome oxidase c assembly FHA PF00498.26 PVD28645.1 - 6.1e-18 64.9 0.1 1.1e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD28645.1 - 4.9e-05 23.6 0.0 0.003 17.8 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain UPF0242 PF06785.11 PVD28645.1 - 2.4 8.2 8.4 4 7.5 8.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 PVD28645.1 - 6.3 5.5 8.6 8.5 5.1 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-1a PF01176.19 PVD28646.1 - 2.4e-21 75.3 0.0 4.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 BLOC1S3 PF15753.5 PVD28646.1 - 1.6e-11 44.6 2.2 3.2e-11 43.7 2.2 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4592 PF15262.6 PVD28646.1 - 0.57 10.9 3.0 1 10.0 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Calcipressin PF04847.12 PVD28647.1 - 1.4e-17 64.1 1.8 1.5e-17 64.0 1.8 1.1 1 0 0 1 1 1 1 Calcipressin Ank_2 PF12796.7 PVD28650.1 - 9.9e-36 122.2 7.4 2.4e-14 53.7 0.3 3.7 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD28650.1 - 1.1e-32 112.0 6.7 5.7e-10 39.5 0.3 5.6 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD28650.1 - 1.5e-25 88.5 19.5 0.0016 18.8 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 PVD28650.1 - 3.5e-24 82.2 10.4 0.034 14.7 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD28650.1 - 2.2e-22 78.8 12.9 8.9e-07 29.1 0.1 6.0 2 1 6 8 8 8 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD28650.1 - 1.1e-07 32.1 2.0 1.1e-07 32.1 2.0 1.9 2 0 0 2 2 2 1 SOCS box PSD2 PF07624.11 PVD28650.1 - 0.14 11.9 0.1 0.47 10.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) zf-H2C2_2 PF13465.6 PVD28653.1 - 4.7e-29 99.5 35.1 2.1e-07 31.0 0.6 6.0 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD28653.1 - 5.1e-18 64.5 40.5 1.1e-05 25.6 3.0 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD28653.1 - 3.3e-12 46.2 37.4 0.00057 20.5 2.4 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD28653.1 - 9.4e-07 28.7 10.7 6.7e-05 22.8 2.4 5.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD28653.1 - 2.7e-05 24.3 21.1 0.016 15.5 0.1 5.8 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD28653.1 - 0.0018 18.6 28.2 0.029 14.8 0.7 6.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type BolA PF01722.18 PVD28653.1 - 0.033 14.5 1.9 17 5.8 0.2 3.3 1 1 1 3 3 3 0 BolA-like protein Zn-ribbon_8 PF09723.10 PVD28653.1 - 0.32 11.1 12.2 3.3 7.9 1.2 4.1 3 1 0 3 3 3 0 Zinc ribbon domain zf-MYST PF17772.1 PVD28653.1 - 0.54 9.9 4.1 2.6 7.7 0.1 3.2 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 PVD28653.1 - 1.2 9.0 21.4 0.11 12.3 0.7 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 PVD28653.1 - 1.7 9.4 10.5 6.7 7.4 1.2 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 PVD28653.1 - 3.2 8.1 20.0 2.4 8.6 3.9 4.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 PVD28653.1 - 6.4 6.9 10.1 1.2e+03 -0.4 10.1 2.9 1 1 0 1 1 1 0 Double zinc ribbon DSPc PF00782.20 PVD28654.1 - 4.7e-36 123.5 0.2 8.7e-36 122.7 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD28654.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PVD28654.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ank_4 PF13637.6 PVD28655.1 - 2e-10 41.0 3.7 7.7e-07 29.6 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD28655.1 - 5e-07 29.5 6.3 0.00033 20.9 0.3 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PVD28655.1 - 8.5e-07 29.1 1.1 8.7e-05 22.7 0.2 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD28655.1 - 1e-06 29.2 1.1 0.00019 21.9 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD28655.1 - 3.3e-05 24.1 6.1 0.00062 20.1 0.8 3.4 2 0 0 2 2 2 1 Ankyrin repeat WD40 PF00400.32 PVD28656.1 - 5.1e-07 30.3 13.7 0.2 12.6 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 PVD28656.1 - 0.001 19.5 0.1 8.3 7.0 0.0 3.9 4 0 0 4 4 4 2 PQQ-like domain DUF346 PF03984.13 PVD28656.1 - 0.11 12.3 1.7 3 7.7 0.1 3.2 3 0 0 3 3 3 0 Repeat of unknown function (DUF346) DUF4732 PF15876.5 PVD28657.1 - 0.0056 16.8 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4732) DUF3854 PF12965.7 PVD28657.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Biopterin_H PF00351.21 PVD28658.1 - 7.6e-25 87.6 1.1 8.5e-25 87.5 0.1 1.6 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 PVD28658.1 - 5.4e-05 22.9 0.2 9.1e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 PVD28658.1 - 0.0036 17.9 1.9 0.0064 17.1 1.1 1.8 2 0 0 2 2 2 1 ACT domain Biopterin_H PF00351.21 PVD28659.1 - 4.8e-71 239.5 0.0 5.4e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Cullin PF00888.22 PVD28660.1 - 6.5e-184 613.0 10.0 8.7e-184 612.6 10.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PVD28660.1 - 2.5e-18 65.9 4.7 6.4e-18 64.5 4.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 PVD28660.1 - 0.054 13.7 2.2 0.18 12.0 0.4 2.5 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Prefoldin PF02996.17 PVD28661.1 - 3.1e-33 114.2 0.1 4.9e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 PVD28661.1 - 0.052 13.5 0.4 2.5 8.1 0.0 2.6 2 1 0 2 2 2 0 Prefoldin subunit DUF1359 PF07097.11 PVD28661.1 - 0.093 13.0 0.9 0.7 10.2 0.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1359) RabGAP-TBC PF00566.18 PVD28662.1 - 2.1e-47 161.5 7.0 3.4e-47 160.9 7.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.22 PVD28663.1 - 1.8e-56 190.2 0.0 2.1e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28663.1 - 3.7e-36 124.0 0.0 5.7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28663.1 - 4.8e-14 52.2 0.0 5.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD28663.1 - 0.00067 19.1 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD28663.1 - 0.00095 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD28663.1 - 0.0073 16.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD28663.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain GCFC PF07842.12 PVD28664.1 - 5.9e-82 275.4 15.3 5.9e-82 275.4 15.3 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 PVD28664.1 - 6.3e-20 71.5 3.1 1.8e-19 70.0 3.1 1.8 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 PVD28664.1 - 1.4e-15 56.9 2.2 2.6e-15 56.0 2.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD28664.1 - 0.00092 19.3 1.2 0.0022 18.1 1.2 1.7 1 0 0 1 1 1 1 G-patch domain Rab5-bind PF09311.11 PVD28664.1 - 0.0077 15.7 5.7 0.3 10.5 5.9 2.3 1 1 0 1 1 1 1 Rabaptin-like protein DNA_gyraseA_C PF03989.13 PVD28664.1 - 0.14 11.7 0.2 0.32 10.5 0.2 1.6 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Baculo_PEP_C PF04513.12 PVD28665.1 - 0.0048 16.9 2.4 0.011 15.8 2.4 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 PVD28665.1 - 0.012 15.2 4.1 0.012 15.2 4.1 1.6 2 0 0 2 2 2 0 Intermediate filament protein Sipho_Gp157 PF05565.11 PVD28665.1 - 0.12 12.3 2.8 0.24 11.4 2.8 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 Laminin_II PF06009.12 PVD28665.1 - 0.19 11.7 4.8 0.37 10.8 4.8 1.4 1 0 0 1 1 1 0 Laminin Domain II Allexi_40kDa PF05549.11 PVD28665.1 - 0.36 10.3 5.9 0.046 13.2 0.9 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein Selenoprotein_S PF06936.11 PVD28665.1 - 0.71 9.7 4.0 0.18 11.6 0.6 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1664 PF07889.12 PVD28665.1 - 0.79 9.8 5.4 2.1 8.4 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 PVD28665.1 - 0.8 10.1 3.9 1.4 9.4 1.4 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 PVD28665.1 - 2.2 6.3 12.8 0.25 9.4 7.7 1.8 2 0 0 2 2 2 0 HOOK protein TEX13 PF15186.6 PVD28665.1 - 2.7 7.7 8.4 0.93 9.2 4.5 2.0 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Jnk-SapK_ap_N PF09744.9 PVD28665.1 - 3.5 7.9 11.4 0.086 13.1 4.3 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Phage_GPO PF05929.11 PVD28665.1 - 3.5 7.2 8.1 0.25 10.9 2.6 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 PVD28665.1 - 4.1 7.6 12.5 0.16 12.2 5.7 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 PVD28665.1 - 7.2 6.7 17.5 0.44 10.6 7.6 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 PVD28665.1 - 8.4 6.9 15.3 0.15 12.6 7.5 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 RR_TM4-6 PF06459.12 PVD28666.1 - 0.54 10.0 7.0 0.64 9.8 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SNase PF00565.17 PVD28667.1 - 3.9e-08 33.7 0.0 5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Exo_endo_phos PF03372.23 PVD28668.1 - 3.6e-05 23.4 0.0 6.6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD28668.1 - 0.01 15.6 0.0 0.072 12.9 0.0 2.1 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase SNase PF00565.17 PVD28669.1 - 1.1e-46 157.8 0.5 1.6e-17 63.9 0.0 4.2 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 PVD28669.1 - 4.3e-29 101.0 0.0 1.1e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 PVD28669.1 - 0.07 13.6 0.0 2 9.0 0.0 2.9 2 0 0 2 2 2 0 Agenet domain Iron_permease PF04120.12 PVD28669.1 - 0.15 11.8 0.0 9.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Low affinity iron permease SDF PF00375.18 PVD28670.1 - 3.2e-05 23.1 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 PVD28671.1 - 1.2e-34 120.0 6.3 1.7e-34 119.5 6.3 1.3 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family CheF-arch PF04283.12 PVD28671.1 - 0.009 15.8 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Chemotaxis signal transduction system protein F from archaea DUF4064 PF13273.6 PVD28671.1 - 0.85 9.9 13.6 4.4 7.6 13.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) BIR PF00653.21 PVD28672.1 - 1e-19 71.0 1.8 1e-19 71.0 1.8 2.9 2 1 1 3 3 3 1 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD28672.1 - 5.1e-14 51.9 8.6 5.1e-14 51.9 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28672.1 - 1.9e-06 27.7 9.0 1.9e-06 27.7 9.0 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD28672.1 - 0.00043 20.6 10.7 0.00043 20.6 10.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD28672.1 - 0.0061 16.4 12.4 0.015 15.2 12.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD28672.1 - 0.18 11.9 4.7 0.58 10.2 4.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28672.1 - 0.33 10.9 15.4 0.064 13.2 10.7 2.2 2 1 0 2 2 2 0 zinc-RING finger domain DUF1644 PF07800.12 PVD28672.1 - 4.3 7.4 9.5 11 6.0 0.5 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1644) zf-C2H2 PF00096.26 PVD28673.1 - 5.5e-15 54.9 27.0 0.00047 20.4 0.3 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD28673.1 - 1.4e-11 44.1 27.8 0.0045 17.7 1.3 5.7 5 1 1 6 6 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD28673.1 - 8.9e-09 35.4 20.7 0.00013 22.2 0.1 5.8 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD28673.1 - 9.9e-06 25.7 2.0 1.9 8.9 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD28673.1 - 0.00071 19.9 4.0 4.5 7.8 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-BED PF02892.15 PVD28673.1 - 0.001 19.1 17.2 0.011 15.7 0.2 4.0 4 0 0 4 4 4 2 BED zinc finger zf-C2H2_2 PF12756.7 PVD28673.1 - 0.029 14.7 6.0 16 5.9 0.1 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 PVD28673.1 - 0.032 14.1 0.4 0.79 9.6 0.0 2.9 2 0 0 2 2 2 0 HNH endonuclease Talin_middle PF09141.10 PVD28673.1 - 0.056 13.5 0.4 0.094 12.7 0.4 1.2 1 0 0 1 1 1 0 Talin, middle domain zf-C2H2_6 PF13912.6 PVD28673.1 - 0.097 12.7 17.8 6.7 6.8 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 PVD28673.1 - 0.098 12.2 0.5 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-MYST PF17772.1 PVD28673.1 - 1.2 8.8 3.5 62 3.3 0.0 4.0 4 0 0 4 4 4 0 MYST family zinc finger domain ADK_lid PF05191.14 PVD28673.1 - 9.1 6.4 10.2 1.4e+02 2.5 10.2 2.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid Radial_spoke_3 PF06098.11 PVD28674.1 - 3.3e-97 325.2 20.3 3.2e-96 322.0 20.3 2.0 1 1 0 1 1 1 1 Radial spoke protein 3 MCU PF04678.13 PVD28674.1 - 0.25 11.4 4.6 0.5 10.4 4.6 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter CemA PF03040.14 PVD28674.1 - 0.51 10.2 3.9 0.91 9.4 3.9 1.3 1 0 0 1 1 1 0 CemA family DUF2052 PF09747.9 PVD28674.1 - 2.5 8.2 15.3 0.88 9.7 9.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) WD40 PF00400.32 PVD28675.1 - 1.2e-15 57.7 4.8 0.0014 19.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28675.1 - 1.1e-06 28.9 0.1 0.22 11.8 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 PVD28675.1 - 0.043 13.5 0.2 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF4585 PF15232.6 PVD28675.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) NAD_synthase PF02540.17 PVD28676.1 - 1.8e-25 89.5 0.0 6.4e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 PVD28676.1 - 2.3e-17 63.2 0.0 4.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 PVD28676.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase Alb1 PF09135.11 PVD28676.1 - 0.18 12.7 3.5 0.37 11.7 3.5 1.5 1 0 0 1 1 1 0 Alb1 C2 PF00168.30 PVD28677.1 - 1.9e-52 175.8 0.0 2.7e-27 95.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD28677.1 - 3.4e-05 23.4 0.1 0.41 10.2 0.1 2.9 3 0 0 3 3 3 2 CEP76 C2 domain PI3K_C2 PF00792.24 PVD28677.1 - 0.0098 15.8 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 X PF00739.19 PVD28677.1 - 0.084 13.0 0.1 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Trans-activation protein X zf-C3HC4_3 PF13920.6 PVD28678.1 - 1.8e-11 43.7 16.1 1.8e-11 43.7 16.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 PVD28678.1 - 5.6e-07 30.1 0.4 5.6e-07 30.1 0.4 3.2 3 0 0 3 3 3 1 Inhibitor of Apoptosis domain Prok-RING_4 PF14447.6 PVD28678.1 - 8.5e-05 22.3 13.8 0.00019 21.2 13.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD28678.1 - 0.21 12.0 18.0 0.62 10.5 18.0 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PVD28678.1 - 4.6 7.3 19.2 1.5 8.8 15.8 2.0 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 PVD28679.1 - 0.00014 21.8 8.4 0.00045 20.2 2.1 3.8 3 1 1 4 4 4 2 Double zinc ribbon DUF5038 PF16441.5 PVD28679.1 - 0.00034 20.7 0.4 11 6.0 0.0 3.4 1 1 1 3 3 3 3 Domain of unknown function (DUF5038) zinc_ribbon_2 PF13240.6 PVD28679.1 - 0.018 14.8 0.4 0.018 14.8 0.4 4.1 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 PVD28679.1 - 1 9.3 7.5 0.87 9.6 0.1 3.9 4 0 0 4 4 4 0 Nudix N-terminal zf-ribbon_3 PF13248.6 PVD28679.1 - 3.2 7.3 21.1 1 8.9 0.2 4.8 4 1 1 5 5 5 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 PVD28679.1 - 3.4 7.8 12.6 2.4 8.2 0.2 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain PNMA PF14893.6 PVD28680.1 - 0.008 15.6 0.1 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 PNMA DUF1759 PF03564.15 PVD28680.1 - 0.064 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.17 PVD28680.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 PVD28681.1 - 2.4e-06 27.2 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PVD28682.1 - 7.3e-30 103.0 0.1 1.2e-28 99.1 0.0 3.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD28682.1 - 4e-28 97.8 1.6 5.6e-27 94.1 0.1 3.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD28682.1 - 0.0002 21.0 0.0 0.00063 19.3 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_5 PF13102.6 PVD28682.1 - 0.088 13.2 0.8 3.2 8.1 0.0 3.4 3 0 0 3 3 3 0 Phage integrase SAM-like domain zf-C3HC4_3 PF13920.6 PVD28683.1 - 0.00013 21.7 7.6 0.00013 21.7 7.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD28683.1 - 0.00078 19.4 12.2 0.011 15.7 8.6 3.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD28683.1 - 0.0011 18.7 14.2 0.071 13.0 10.8 3.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GCIP PF13324.6 PVD28683.1 - 0.0032 17.1 8.9 0.0091 15.6 8.9 1.8 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Prok-RING_4 PF14447.6 PVD28683.1 - 0.005 16.7 7.4 0.005 16.7 7.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF3677 PF12432.8 PVD28683.1 - 0.0053 17.0 4.3 0.01 16.1 0.2 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) Siva PF05458.12 PVD28683.1 - 0.0084 15.8 0.3 0.021 14.5 0.3 1.6 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-C3HC4 PF00097.25 PVD28683.1 - 0.022 14.6 16.6 0.11 12.4 10.9 3.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28683.1 - 0.023 15.0 12.5 0.065 13.6 9.3 3.3 2 0 0 2 2 2 0 Ring finger domain Sigma70_ner PF04546.13 PVD28683.1 - 0.37 10.7 15.5 0.45 10.4 13.3 2.3 2 0 0 2 2 1 0 Sigma-70, non-essential region zf-RING_UBOX PF13445.6 PVD28683.1 - 0.52 10.4 7.9 3.7 7.7 7.9 2.6 1 0 0 1 1 1 0 RING-type zinc-finger RXT2_N PF08595.11 PVD28683.1 - 1.1 9.3 10.2 3.9 7.5 10.2 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 PVD28683.1 - 1.1 9.7 16.8 4.5 7.7 16.8 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_10 PF16685.5 PVD28683.1 - 1.9 8.7 7.6 5.2 7.3 3.6 3.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 FAM176 PF14851.6 PVD28683.1 - 1.9 8.2 6.0 5.1 6.8 6.0 1.7 1 0 0 1 1 1 0 FAM176 family UPF0547 PF10571.9 PVD28683.1 - 2.3 8.4 4.9 0.43 10.7 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 PVD28683.1 - 5.9 7.0 12.5 4.4 7.4 8.6 2.8 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 PVD28683.1 - 8.5 6.5 11.3 12 6.1 6.0 3.1 2 0 0 2 2 2 0 Double zinc ribbon ANF_receptor PF01094.28 PVD28684.1 - 2.4e-44 151.9 0.0 4.9e-44 150.9 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD28684.1 - 1.4e-34 119.9 17.3 7.1e-26 91.4 8.5 2.5 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 PVD28684.1 - 1e-14 55.0 0.0 9.8e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein CD225 PF04505.12 PVD28685.1 - 0.0033 17.5 1.0 0.0047 17.0 1.0 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Herpes_glycop PF01528.16 PVD28685.1 - 0.039 12.8 0.5 0.039 12.8 0.5 1.5 1 1 1 2 2 2 0 Herpesvirus glycoprotein M PB1 PF00564.24 PVD28686.1 - 3.6e-10 39.6 0.2 5.6e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 PB1 domain KAR9 PF08580.10 PVD28686.1 - 0.012 14.2 1.5 0.014 14.0 1.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GTP_EFTU_D2 PF03144.25 PVD28686.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 TFIIA PF03153.13 PVD28686.1 - 4.5 7.2 24.5 5.8 6.8 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0240 PF06784.11 PVD28687.1 - 1.2e-48 165.4 2.2 1.5e-48 165.2 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) ELMO_CED12 PF04727.13 PVD28687.1 - 0.071 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 ELMO/CED-12 family Catalase PF00199.19 PVD28688.1 - 5.8e-168 558.9 2.4 8.1e-151 502.5 1.6 2.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 PVD28688.1 - 4.5e-21 74.8 0.0 1.5e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive AT_hook PF02178.19 PVD28689.1 - 0.018 14.9 3.0 0.07 13.0 3.0 2.1 1 0 0 1 1 1 0 AT hook motif zf-H2C2_5 PF13909.6 PVD28690.1 - 6.8e-23 80.1 82.7 3.4e-07 29.9 0.5 11.0 10 1 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD28690.1 - 3.3e-18 65.0 89.6 0.00054 20.3 0.7 10.6 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD28690.1 - 1.3e-15 57.0 72.9 1.4e-05 25.3 0.6 12.0 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD28690.1 - 1.6e-12 47.1 79.9 0.17 12.8 0.4 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-Di19 PF05605.12 PVD28690.1 - 0.0015 18.8 52.4 0.025 14.8 5.1 6.6 4 2 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 PVD28690.1 - 0.0055 17.4 3.6 0.0055 17.4 3.6 5.1 2 1 4 6 6 6 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_3 PF13878.6 PVD28690.1 - 0.056 13.3 0.1 0.056 13.3 0.1 4.8 4 1 1 5 5 5 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_2 PF12756.7 PVD28690.1 - 1.7 9.1 58.0 13 6.2 15.1 8.5 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 PVD28690.1 - 2.8 7.0 46.0 1.2 8.2 1.1 7.0 2 2 5 7 7 7 0 Putative actin-like family TPR_2 PF07719.17 PVD28691.1 - 1.9e-32 108.7 6.9 2.1e-07 30.5 0.0 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat DUF1736 PF08409.11 PVD28691.1 - 1.6e-31 108.1 0.5 4.2e-31 106.8 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 PVD28691.1 - 2.6e-31 106.2 13.7 1e-07 31.5 0.1 8.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD28691.1 - 6.5e-30 102.5 8.0 2e-08 33.7 0.0 8.8 8 1 1 9 9 9 7 TPR repeat TPR_8 PF13181.6 PVD28691.1 - 5.6e-28 94.8 0.3 6.6e-05 22.8 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD28691.1 - 8.4e-28 96.8 1.4 7e-13 49.0 0.0 5.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 PVD28691.1 - 2.6e-24 83.8 12.8 0.00039 20.6 0.0 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28691.1 - 1.6e-22 79.8 11.9 2.4e-06 27.9 0.1 7.4 2 1 5 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 PVD28691.1 - 2e-21 76.1 9.6 0.00012 22.3 0.0 7.1 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD28691.1 - 3.9e-17 61.5 8.8 0.17 12.8 0.0 9.4 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 PVD28691.1 - 9e-14 51.1 0.0 0.041 14.5 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD28691.1 - 1.2e-12 47.7 4.5 0.0049 17.0 0.2 5.8 2 1 4 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 PVD28691.1 - 9.1e-12 44.1 4.6 0.037 14.1 0.0 6.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD28691.1 - 6.7e-09 35.3 10.4 0.13 12.2 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD28691.1 - 2.6e-08 33.7 5.4 0.0001 21.9 0.1 4.0 2 1 2 4 4 4 2 Coatomer epsilon subunit ANAPC3 PF12895.7 PVD28691.1 - 2e-07 31.1 4.2 0.24 11.6 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PVD28691.1 - 5.4e-06 26.4 0.8 0.36 10.9 0.1 4.8 4 1 1 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 PVD28691.1 - 2.2e-05 24.0 4.5 0.00059 19.3 0.2 2.6 2 0 0 2 2 2 1 MalT-like TPR region NARP1 PF12569.8 PVD28691.1 - 0.00041 19.4 3.6 0.012 14.6 0.1 3.1 3 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 PVD28691.1 - 0.00044 19.5 1.2 0.24 10.6 0.1 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PVD28691.1 - 0.01 15.5 0.5 0.32 10.6 0.0 3.3 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 PVD28691.1 - 0.012 16.1 2.8 3.9 8.4 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD28691.1 - 0.015 15.0 4.8 0.65 9.7 0.0 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain BTAD PF03704.17 PVD28691.1 - 0.046 14.2 0.4 0.38 11.2 0.1 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 PVD28691.1 - 0.071 13.4 9.0 15 6.0 0.2 5.0 3 2 3 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 PVD28691.1 - 0.072 12.5 2.0 18 4.6 0.1 3.4 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP PknG_TPR PF16918.5 PVD28691.1 - 0.13 11.0 0.1 5.2 5.7 0.0 2.5 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Sel1 PF08238.12 PVD28691.1 - 0.18 12.5 1.4 13 6.7 0.1 4.1 4 0 0 4 4 3 0 Sel1 repeat ANAPC5 PF12862.7 PVD28691.1 - 1.2 9.2 4.1 40 4.4 1.4 3.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 ECSCR PF15820.5 PVD28693.1 - 0.12 12.3 1.4 0.13 12.1 0.3 1.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 PVD28693.1 - 0.3 12.0 1.3 0.46 11.4 1.3 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Astacin PF01400.24 PVD28694.1 - 8.8e-28 97.2 2.6 1.1e-25 90.4 0.6 2.2 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Kringle PF00051.18 PVD28694.1 - 5.1e-18 65.2 7.6 2.3e-17 63.1 7.6 2.1 1 1 0 1 1 1 1 Kringle domain Peptidase_M10 PF00413.24 PVD28694.1 - 0.0011 18.9 0.3 0.18 11.7 0.0 2.3 2 0 0 2 2 2 2 Matrixin SPATIAL PF15256.6 PVD28694.1 - 0.83 10.0 5.9 1.2 9.4 5.9 1.3 1 0 0 1 1 1 0 SPATIAL C1q PF00386.21 PVD28696.1 - 3.5e-13 49.9 0.0 6.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 C1q domain DUF1664 PF07889.12 PVD28696.1 - 0.00063 19.8 0.1 0.0039 17.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 PVD28696.1 - 0.002 18.0 1.1 0.0056 16.5 1.0 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 PVD28696.1 - 0.0023 18.5 1.0 0.32 11.7 0.1 2.2 1 1 1 2 2 2 1 Initiation control protein YabA Leu_zip PF15294.6 PVD28696.1 - 0.0045 16.5 0.1 0.0087 15.6 0.1 1.4 1 1 0 1 1 1 1 Leucine zipper Dor1 PF04124.12 PVD28696.1 - 0.0062 15.3 0.0 0.0076 15.0 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family GAS PF13851.6 PVD28696.1 - 0.0087 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 PVD28696.1 - 0.011 15.4 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 PVD28696.1 - 0.035 13.0 0.1 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PVD28696.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 PVD28696.1 - 0.092 13.2 1.1 3.1 8.3 0.8 2.7 2 1 0 2 2 2 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 PVD28696.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_1 PF00170.21 PVD28696.1 - 0.13 12.4 1.5 7.6 6.7 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Laminin_II PF06009.12 PVD28696.1 - 0.14 12.1 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II HMMR_C PF15908.5 PVD28696.1 - 0.15 12.3 0.7 8.7 6.6 0.1 2.5 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal UPF0449 PF15136.6 PVD28696.1 - 0.15 12.6 0.3 7.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.12 PVD28696.1 - 0.16 12.1 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 PVD28696.1 - 0.17 11.6 0.4 0.51 10.1 0.4 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 PVD28696.1 - 0.25 11.8 0.5 19 5.7 0.1 2.6 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 PVD28696.1 - 0.27 11.3 1.7 12 6.0 0.8 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4515 PF14988.6 PVD28696.1 - 0.31 10.8 0.8 21 4.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) HAP1_N PF04849.13 PVD28696.1 - 0.8 8.8 3.1 8.5 5.5 0.1 2.1 1 1 0 2 2 2 0 HAP1 N-terminal conserved region HALZ PF02183.18 PVD28696.1 - 2.5 8.4 4.9 4 7.7 1.2 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_UBOX PF13445.6 PVD28697.1 - 9.9e-09 35.1 0.7 9.9e-09 35.1 0.7 3.3 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD28697.1 - 3.2e-05 23.7 1.1 3.2e-05 23.7 1.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD28697.1 - 4.2e-05 23.4 7.8 4.2e-05 23.4 7.8 3.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD28697.1 - 4.9e-05 23.6 2.0 4.9e-05 23.6 2.0 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD28697.1 - 0.00046 20.0 1.0 0.00046 20.0 1.0 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD28697.1 - 0.0034 17.5 1.8 0.0034 17.5 1.8 3.5 2 1 2 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 PVD28697.1 - 0.0055 16.4 1.8 0.02 14.6 1.8 2.0 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 PVD28697.1 - 0.0061 16.4 1.0 0.0061 16.4 1.0 2.6 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-HIT PF04438.16 PVD28697.1 - 0.091 12.6 14.9 0.87 9.5 11.1 3.1 2 1 0 2 2 2 0 HIT zinc finger ArfGap PF01412.18 PVD28697.1 - 0.23 11.5 4.4 0.59 10.2 4.4 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf C1_4 PF07975.12 PVD28697.1 - 0.33 11.2 9.6 0.52 10.6 5.2 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain C1_2 PF03107.16 PVD28697.1 - 0.67 10.3 13.0 0.076 13.3 7.5 2.2 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 PVD28697.1 - 1.7 8.7 19.2 6.1 7.0 11.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 PVD28697.1 - 2.6 8.1 14.2 3.3 7.8 8.8 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain Siva PF05458.12 PVD28697.1 - 3.4 7.3 11.0 7.9 6.1 6.2 2.3 1 1 1 2 2 2 0 Cd27 binding protein (Siva) C1q PF00386.21 PVD28698.1 - 2.5e-12 47.1 0.0 9e-12 45.3 0.0 2.1 2 0 0 2 2 1 1 C1q domain CENP-F_leu_zip PF10473.9 PVD28698.1 - 1.7e-06 28.1 26.3 0.016 15.3 9.7 4.5 2 1 3 5 5 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_UBOX PF13445.6 PVD28698.1 - 1.2e-05 25.3 3.0 1.2e-05 25.3 3.0 2.3 3 0 0 3 3 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28698.1 - 2.2e-05 24.3 6.4 2.2e-05 24.3 6.4 2.7 2 1 0 2 2 1 1 zinc-RING finger domain HALZ PF02183.18 PVD28698.1 - 2.5e-05 24.4 23.6 0.024 14.8 0.2 6.9 6 2 1 7 7 7 1 Homeobox associated leucine zipper ATG16 PF08614.11 PVD28698.1 - 8.8e-05 22.8 8.2 8.8e-05 22.8 8.2 5.2 3 2 2 5 5 5 1 Autophagy protein 16 (ATG16) zf-B_box PF00643.24 PVD28698.1 - 0.00095 19.3 9.3 0.00095 19.3 9.3 4.0 4 1 0 4 4 3 1 B-box zinc finger TolA_bind_tri PF16331.5 PVD28698.1 - 0.0021 18.1 25.9 0.7 10.0 0.4 6.6 3 1 3 7 7 6 2 TolA binding protein trimerisation KASH_CCD PF14662.6 PVD28698.1 - 0.0061 16.4 9.8 0.0061 16.4 9.8 4.6 3 1 0 4 4 2 1 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 PVD28698.1 - 0.0062 16.6 3.7 0.0062 16.6 3.7 5.7 4 1 1 6 6 5 2 Afadin- and alpha -actinin-Binding zf-C3HC4 PF00097.25 PVD28698.1 - 0.0076 16.1 6.6 0.0076 16.1 6.6 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28698.1 - 0.0099 16.2 10.3 0.0099 16.2 10.3 3.2 2 1 0 2 2 2 1 Ring finger domain DUF2730 PF10805.8 PVD28698.1 - 0.01 15.9 16.3 0.02 15.0 0.5 5.2 3 2 1 5 5 5 0 Protein of unknown function (DUF2730) ERM PF00769.19 PVD28698.1 - 0.01 15.6 0.7 0.01 15.6 0.7 4.3 3 2 1 4 4 4 0 Ezrin/radixin/moesin family ZapB PF06005.12 PVD28698.1 - 0.014 15.9 17.4 16 6.0 0.1 5.8 2 1 3 5 5 5 0 Cell division protein ZapB zf-RING_11 PF17123.5 PVD28698.1 - 0.025 14.3 1.9 0.11 12.3 2.0 2.2 1 1 0 1 1 1 0 RING-like zinc finger PI3K_P85_iSH2 PF16454.5 PVD28698.1 - 0.066 12.8 23.6 21 4.7 4.9 5.6 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BRE1 PF08647.11 PVD28698.1 - 0.074 13.1 22.5 2.1 8.5 1.6 4.8 2 1 2 5 5 5 0 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 PVD28698.1 - 0.11 12.2 23.1 0.066 13.0 7.9 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) HMMR_C PF15908.5 PVD28698.1 - 0.12 12.6 19.3 5.6 7.2 0.1 5.6 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor C-terminal TRAF_BIRC3_bd PF16673.5 PVD28698.1 - 0.13 12.1 3.3 0.38 10.6 1.2 2.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF148 PF02520.17 PVD28698.1 - 0.21 11.7 6.9 3.4 7.8 0.0 3.7 3 1 1 4 4 3 0 Domain of unknown function DUF148 APG6_N PF17675.1 PVD28698.1 - 0.28 11.7 32.0 1.5 9.4 0.2 5.2 2 2 2 4 4 3 0 Apg6 coiled-coil region YabA PF06156.13 PVD28698.1 - 0.7 10.6 23.8 5.7 7.6 1.2 5.9 2 1 4 6 6 6 0 Initiation control protein YabA Taxilin PF09728.9 PVD28698.1 - 0.75 8.9 23.5 0.0082 15.3 10.8 3.2 2 1 1 3 3 3 0 Myosin-like coiled-coil protein DUF5082 PF16888.5 PVD28698.1 - 1.1 9.5 19.8 1.5 9.1 6.2 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) PI_PP_I PF18363.1 PVD28698.1 - 1.1 9.4 3.7 34 4.7 0.2 3.8 1 1 2 4 4 4 0 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 PVD28698.1 - 1.4 9.0 26.4 0.095 12.7 3.9 4.8 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 PVD28698.1 - 2.9 7.2 26.7 0.39 10.0 3.6 4.5 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 PVD28698.1 - 3.6 7.8 19.0 5.5 7.2 0.1 5.4 2 2 3 5 5 5 0 Centrosomin N-terminal motif 1 CEBP_ZZ PF16366.5 PVD28698.1 - 4.3 7.7 13.9 4.6 7.5 1.0 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Siva PF05458.12 PVD28698.1 - 4.4 7.0 15.0 1.5 8.5 2.3 2.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DivIC PF04977.15 PVD28698.1 - 5.2 6.9 31.6 5.1 6.9 0.1 7.1 3 1 5 8 8 7 0 Septum formation initiator Prok-RING_4 PF14447.6 PVD28698.1 - 7.9 6.4 22.0 1.8 8.5 5.7 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 C1q PF00386.21 PVD28699.1 - 2.1e-08 34.4 0.3 6.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 C1q domain RapA_C PF12137.8 PVD28699.1 - 0.0057 15.7 5.9 0.01 14.9 5.9 1.3 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal zf-C3HC4 PF00097.25 PVD28699.1 - 0.013 15.4 7.2 0.013 15.4 7.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD28699.1 - 0.031 14.3 7.2 0.099 12.7 7.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger 7TM_GPCR_Srx PF10328.9 PVD28700.1 - 0.00033 20.4 14.4 0.033 13.8 3.2 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD28700.1 - 0.00074 18.9 11.0 0.031 13.6 1.8 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Phage_holin_Dp1 PF16938.5 PVD28700.1 - 0.0013 18.9 0.2 1.8 8.8 0.0 2.7 2 0 0 2 2 2 2 Putative phage holin Dp-1 7TM_GPCR_Srt PF10321.9 PVD28700.1 - 0.045 12.7 14.5 0.15 11.0 3.9 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt MPC PF03650.13 PVD28700.1 - 0.34 11.1 3.1 1.7 8.8 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers MgtC PF02308.16 PVD28700.1 - 0.37 11.2 5.9 3.4 8.0 1.4 2.5 1 1 1 2 2 2 0 MgtC family Pkr1 PF08636.10 PVD28700.1 - 5.7 7.2 8.5 18 5.5 0.9 2.6 2 0 0 2 2 2 0 ER protein Pkr1 TNF PF00229.18 PVD28702.1 - 5.2e-14 52.3 0.0 1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 PVD28703.1 - 6.6e-18 64.9 0.0 1.5e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF4190 PF13828.6 PVD28703.1 - 0.092 12.5 1.3 0.14 11.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF2973 PF11189.8 PVD28703.1 - 0.18 11.9 0.3 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) TNF PF00229.18 PVD28704.1 - 6.3e-06 26.2 0.5 1.1e-05 25.3 0.5 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 PVD28705.1 - 2.5e-20 72.7 0.3 4.3e-20 72.0 0.3 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family VirB8 PF04335.13 PVD28705.1 - 0.25 11.2 1.6 0.47 10.3 1.6 1.4 1 0 0 1 1 1 0 VirB8 protein TNF PF00229.18 PVD28706.1 - 7.5e-13 48.5 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Rax2 PF12768.7 PVD28706.1 - 0.033 13.6 0.4 0.062 12.7 0.4 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF761 PF05553.11 PVD28706.1 - 0.035 13.6 2.5 2.1 7.9 0.9 2.3 2 0 0 2 2 2 0 Cotton fibre expressed protein TNF PF00229.18 PVD28707.1 - 9.5e-18 64.4 0.1 2.5e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family BIR PF00653.21 PVD28708.1 - 1.6e-07 31.9 0.4 2.8e-07 31.1 0.4 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Hairy_orange PF07527.13 PVD28710.1 - 2.5e-08 34.0 0.1 1.1e-07 32.0 0.1 2.2 1 0 0 1 1 1 1 Hairy Orange DZR PF12773.7 PVD28711.1 - 0.0014 18.6 7.4 0.01 15.8 7.3 2.4 1 1 1 2 2 2 2 Double zinc ribbon CBM_20 PF00686.19 PVD28711.1 - 0.0071 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain zinc_ribbon_2 PF13240.6 PVD28711.1 - 0.11 12.3 10.5 0.69 9.7 3.6 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 PVD28711.1 - 3.8 7.1 10.7 0.67 9.5 2.8 3.0 3 0 0 3 3 3 0 zinc-ribbon domain AAA_22 PF13401.6 PVD28712.1 - 4.8e-06 26.9 4.3 0.0098 16.2 0.0 5.9 6 0 0 6 6 6 1 AAA domain AAA PF00004.29 PVD28712.1 - 1.1e-05 25.9 0.1 0.0073 16.7 0.0 3.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prok-RING_4 PF14447.6 PVD28712.1 - 0.00012 21.8 7.6 0.00039 20.2 7.6 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 AAA_5 PF07728.14 PVD28712.1 - 0.00019 21.4 0.5 0.0049 16.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PVD28712.1 - 0.00022 20.8 0.3 0.012 15.1 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region ABC_tran PF00005.27 PVD28712.1 - 0.0014 19.2 0.1 0.008 16.7 0.0 2.4 2 0 0 2 2 1 1 ABC transporter zf-RING_5 PF14634.6 PVD28712.1 - 0.0026 17.7 11.8 0.004 17.1 9.0 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD28712.1 - 0.011 16.0 10.7 0.052 13.9 10.7 2.3 1 0 0 1 1 1 0 Ring finger domain NACHT PF05729.12 PVD28712.1 - 0.024 14.6 0.9 6.7 6.6 0.1 3.6 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 PVD28712.1 - 0.038 14.4 0.4 1.8 8.9 0.0 3.8 3 0 0 3 3 3 0 AAA ATPase domain Siva PF05458.12 PVD28712.1 - 0.083 12.6 0.3 0.22 11.2 0.3 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) MCM PF00493.23 PVD28712.1 - 0.14 11.3 0.0 0.45 9.6 0.0 1.9 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 PVD28712.1 - 0.14 12.6 0.1 7.1 7.1 0.0 3.4 3 0 0 3 3 2 0 RNA helicase Sigma54_activ_2 PF14532.6 PVD28712.1 - 0.19 11.8 4.5 1.8 8.7 0.0 4.5 5 0 0 5 5 5 0 Sigma-54 interaction domain zf-C3HC4_2 PF13923.6 PVD28712.1 - 0.82 9.6 17.2 0.052 13.4 10.0 3.0 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 PVD28712.1 - 1 9.4 7.0 5.5 7.1 7.0 2.3 1 0 0 1 1 1 0 zinc-ribbons zf-RING_UBOX PF13445.6 PVD28712.1 - 2.9 8.0 8.1 11 6.1 8.1 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD28712.1 - 7.2 6.6 16.2 0.48 10.3 10.0 2.5 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PVD28712.1 - 7.5 6.7 10.9 3.9 7.6 6.3 2.8 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 PVD28712.1 - 9.5 6.5 8.4 37 4.6 8.4 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ANF_receptor PF01094.28 PVD28713.1 - 1e-22 80.8 0.0 1.9e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 PVD28714.1 - 0.00048 19.3 0.0 0.00048 19.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD28714.1 - 0.0044 16.7 0.0 0.0046 16.7 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 PVD28715.1 - 4.3e-20 72.5 4.8 4.9e-20 72.3 4.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Phage_holin_5_2 PF16079.5 PVD28715.1 - 0.16 12.3 2.8 0.99 9.8 0.5 2.1 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V LapA_dom PF06305.11 PVD28715.1 - 0.83 9.5 3.4 0.6 10.0 0.6 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 7tm_3 PF00003.22 PVD28716.1 - 5.3e-18 65.6 0.5 6.3e-18 65.4 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4006 PF13179.6 PVD28716.1 - 1.2 9.0 3.5 3 7.8 1.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) CD225 PF04505.12 PVD28717.1 - 0.012 15.7 1.3 0.018 15.2 1.3 1.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Herpes_glycop PF01528.16 PVD28717.1 - 0.031 13.1 0.5 0.031 13.1 0.5 1.5 1 1 1 2 2 2 0 Herpesvirus glycoprotein M UPF0240 PF06784.11 PVD28718.1 - 7.4e-49 166.2 2.1 8.9e-49 165.9 2.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Catalase PF00199.19 PVD28719.1 - 3.9e-195 648.3 0.1 4.7e-195 648.1 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PVD28719.1 - 4.5e-21 74.8 0.0 1.5e-20 73.2 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive AlphaC_N PF08829.10 PVD28720.1 - 0.019 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha C protein N terminal BIR PF00653.21 PVD28720.1 - 0.076 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28721.1 - 2.8e-11 43.9 0.0 5.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Macoilin PF09726.9 PVD28721.1 - 7.3 5.0 6.0 8.3 4.8 6.0 1.0 1 0 0 1 1 1 0 Macoilin family zf-C3HC4_3 PF13920.6 PVD28722.1 - 7.7e-08 32.1 9.6 1.3e-07 31.3 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28722.1 - 0.05 13.5 9.9 0.093 12.6 9.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD28722.1 - 0.19 11.7 8.9 0.41 10.6 8.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain RT_RNaseH_2 PF17919.1 PVD28723.1 - 1.9e-14 53.5 0.0 3.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD28723.1 - 1.6e-07 31.5 0.1 4.2e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase 7TM_GPCR_Srw PF10324.9 PVD28724.1 - 1.2e-08 34.6 4.3 1.6e-08 34.2 4.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD28724.1 - 0.0049 16.3 3.9 0.007 15.8 3.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD28724.1 - 0.028 13.8 1.0 0.036 13.4 1.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ndc1_Nup PF09531.10 PVD28724.1 - 0.22 10.2 3.2 0.25 10.0 3.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_UBOX PF13445.6 PVD28725.1 - 1.3e-06 28.3 5.8 1.3e-06 28.3 5.8 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28725.1 - 1.1e-05 25.3 6.0 1.1e-05 25.3 6.0 3.1 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD28725.1 - 0.00084 19.2 6.2 0.00084 19.2 6.2 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD28725.1 - 0.0011 19.1 6.5 0.0011 19.1 6.5 3.2 4 0 0 4 4 2 1 B-box zinc finger DUF2730 PF10805.8 PVD28725.1 - 0.0016 18.5 2.7 0.0088 16.1 0.5 4.3 2 1 3 5 5 5 2 Protein of unknown function (DUF2730) zf-RING_2 PF13639.6 PVD28725.1 - 0.0016 18.7 22.6 0.0028 18.0 8.1 2.8 2 1 0 2 2 2 1 Ring finger domain CENP-F_leu_zip PF10473.9 PVD28725.1 - 0.0026 17.8 32.2 0.11 12.5 7.7 4.1 3 1 1 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.21 PVD28725.1 - 0.01 16.1 4.6 0.01 16.1 4.6 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain SYCE1 PF15233.6 PVD28725.1 - 0.013 15.5 1.2 0.013 15.5 1.2 3.3 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 Leu_zip PF15294.6 PVD28725.1 - 0.022 14.3 21.1 0.043 13.3 15.5 2.6 2 1 0 2 2 2 0 Leucine zipper DUF211 PF02680.14 PVD28725.1 - 0.052 13.7 0.3 0.22 11.7 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 Prefoldin_3 PF13758.6 PVD28725.1 - 0.1 12.7 14.7 0.12 12.4 0.6 3.9 3 1 1 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.20 PVD28725.1 - 0.16 12.0 0.2 0.16 12.0 0.2 4.8 3 3 1 4 4 4 0 Prefoldin subunit PI_PP_I PF18363.1 PVD28725.1 - 0.21 11.8 6.4 0.92 9.7 1.8 2.9 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain UPF0242 PF06785.11 PVD28725.1 - 0.22 11.6 25.5 2.2 8.4 0.7 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 PVD28725.1 - 0.52 10.5 29.4 0.053 13.7 1.2 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4686 PF15742.5 PVD28725.1 - 0.94 8.5 27.6 0.037 13.2 4.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) zf-C3HC4_4 PF15227.6 PVD28725.1 - 0.96 9.7 15.9 4.6 7.5 7.1 3.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1664 PF07889.12 PVD28725.1 - 0.97 9.5 24.2 1.7 8.7 1.4 4.7 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) zf-CHY PF05495.12 PVD28725.1 - 1 9.9 8.6 0.61 10.6 4.0 2.7 1 1 1 2 2 2 0 CHY zinc finger DASH_Dad4 PF08650.10 PVD28725.1 - 1.7 8.7 7.8 3.8 7.5 0.7 3.5 3 0 0 3 3 2 0 DASH complex subunit Dad4 CC2-LZ PF16516.5 PVD28725.1 - 2 8.8 14.5 0.77 10.2 5.1 3.2 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Latarcin PF10279.9 PVD28725.1 - 2.8 8.4 10.2 0.11 13.0 0.9 3.0 3 1 0 3 3 3 0 Latarcin precursor Rx_N PF18052.1 PVD28725.1 - 5 7.5 18.5 0.55 10.5 2.2 4.2 2 1 2 4 4 4 0 Rx N-terminal domain KASH_CCD PF14662.6 PVD28725.1 - 6.8 6.5 29.9 0.12 12.2 16.8 3.1 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4094 PF13334.6 PVD28725.1 - 8.2 6.9 12.3 8.6 6.9 0.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4094) C1q PF00386.21 PVD28726.1 - 1.2e-09 38.4 1.8 5.9e-09 36.2 0.0 2.4 2 1 0 3 3 3 1 C1q domain HALZ PF02183.18 PVD28726.1 - 0.019 15.2 1.3 0.019 15.2 1.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper HMMR_C PF15908.5 PVD28726.1 - 0.026 14.8 8.6 0.15 12.3 2.5 2.3 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal V_ATPase_I PF01496.19 PVD28726.1 - 0.084 10.8 3.6 0.097 10.6 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 PVD28726.1 - 0.096 12.7 14.0 0.39 10.8 7.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_I PF06008.14 PVD28726.1 - 0.1 12.3 14.4 0.4 10.3 14.3 1.9 1 1 1 2 2 2 0 Laminin Domain I YabA PF06156.13 PVD28726.1 - 0.13 12.9 13.7 0.59 10.8 5.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 PVD28726.1 - 0.14 12.3 17.9 0.54 10.4 1.6 3.6 1 1 2 3 3 3 0 TolA binding protein trimerisation KASH_CCD PF14662.6 PVD28726.1 - 0.21 11.4 18.1 0.028 14.2 8.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 PVD28726.1 - 0.23 11.5 18.5 2.3 8.2 18.5 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF572 PF04502.13 PVD28726.1 - 0.27 10.8 7.0 0.34 10.5 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4618 PF15397.6 PVD28726.1 - 0.47 9.8 16.7 1.3 8.4 16.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CLZ PF16526.5 PVD28726.1 - 0.65 10.4 10.4 0.25 11.7 3.3 3.2 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 PVD28726.1 - 0.67 10.5 14.4 4.5 7.8 2.1 3.4 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 PVD28726.1 - 0.76 8.6 16.1 1.5 7.7 12.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 PVD28726.1 - 0.95 8.8 16.6 1.7 7.9 16.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.13 PVD28726.1 - 1 10.1 8.5 0.73 10.6 1.4 2.9 1 1 2 3 3 3 0 Occludin homology domain Fib_alpha PF08702.10 PVD28726.1 - 1.1 9.5 13.9 0.85 9.8 11.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 PVD28726.1 - 1.2 9.7 19.0 0.25 11.8 6.4 3.2 1 1 2 3 3 3 0 Cell division protein ZapB DUF2730 PF10805.8 PVD28726.1 - 1.3 9.1 7.1 3.2 7.9 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 PVD28726.1 - 2.5 8.5 13.1 8.7 6.7 13.2 1.7 1 1 0 1 1 1 0 Fez1 FlaC_arch PF05377.11 PVD28726.1 - 2.9 8.3 16.2 2.5 8.6 4.2 3.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 PVD28726.1 - 3.6 7.4 12.9 9.3 6.0 12.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) HAUS-augmin3 PF14932.6 PVD28726.1 - 3.9 7.0 14.8 8 5.9 14.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 AATF-Che1 PF13339.6 PVD28726.1 - 4.1 8.1 10.7 19 5.9 10.7 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Prefoldin PF02996.17 PVD28726.1 - 4.5 7.2 14.1 0.14 12.0 0.8 3.3 2 1 1 3 3 3 0 Prefoldin subunit ATG16 PF08614.11 PVD28726.1 - 5.2 7.2 16.1 12 6.0 16.1 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 PVD28726.1 - 6.1 7.0 12.9 13 6.0 0.1 3.8 2 1 2 4 4 4 0 bZIP transcription factor UPF0449 PF15136.6 PVD28726.1 - 7.2 7.2 13.0 2.9 8.4 5.2 3.0 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 SLX9 PF15341.6 PVD28726.1 - 7.8 6.9 8.4 15 6.0 8.4 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3450 PF11932.8 PVD28726.1 - 9.1 5.5 17.9 2 7.7 11.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rootletin PF15035.6 PVD28726.1 - 9.2 6.2 14.9 3.3 7.7 6.9 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cnn_1N PF07989.11 PVD28726.1 - 9.7 6.4 14.9 1.4 9.1 4.1 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 zf-RING_UBOX PF13445.6 PVD28727.1 - 7.6e-07 29.1 6.2 7.6e-07 29.1 6.2 3.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28727.1 - 9.1e-06 25.5 6.6 9.1e-06 25.5 6.6 3.5 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD28727.1 - 0.00079 19.2 6.9 0.00079 19.2 6.9 3.5 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28727.1 - 0.0016 18.8 9.3 0.0016 18.8 9.3 3.2 3 1 0 3 3 3 1 Ring finger domain zf-B_box PF00643.24 PVD28727.1 - 0.016 15.3 10.6 0.016 15.3 10.6 4.1 5 0 0 5 5 5 0 B-box zinc finger S8_pro-domain PF16470.5 PVD28727.1 - 0.032 15.0 0.2 0.085 13.6 0.2 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain MADF_DNA_bdg PF10545.9 PVD28727.1 - 0.07 13.4 0.7 0.2 12.0 0.5 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4449 PF14613.6 PVD28727.1 - 0.37 10.9 3.0 0.55 10.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Prefoldin_3 PF13758.6 PVD28727.1 - 0.44 10.6 5.8 0.06 13.4 0.7 2.2 3 0 0 3 3 3 0 Prefoldin subunit IBR PF01485.21 PVD28727.1 - 1.4 9.2 22.3 0.28 11.5 11.9 4.0 2 2 1 3 3 3 0 IBR domain, a half RING-finger domain C1q PF00386.21 PVD28728.1 - 9e-08 32.4 2.6 2.3e-07 31.0 0.0 2.9 3 1 1 4 4 3 1 C1q domain zf-RING_UBOX PF13445.6 PVD28728.1 - 5.6e-07 29.5 6.2 1.2e-06 28.4 5.2 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28728.1 - 2.1e-05 24.4 5.2 2.1e-05 24.4 5.2 3.0 2 2 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 PVD28728.1 - 0.00073 19.6 6.5 0.00073 19.6 6.5 3.2 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD28728.1 - 0.0012 18.6 5.9 0.0012 18.6 5.9 3.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28728.1 - 0.0015 18.8 7.1 0.0015 18.8 7.1 3.0 2 1 0 2 2 2 1 Ring finger domain CENP-F_leu_zip PF10473.9 PVD28728.1 - 0.0023 17.9 25.2 0.0051 16.8 12.2 2.9 3 0 0 3 3 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.21 PVD28728.1 - 0.013 15.7 5.6 0.013 15.7 5.6 3.5 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain SYCE1 PF15233.6 PVD28728.1 - 0.037 14.1 19.0 0.061 13.4 2.9 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Latarcin PF10279.9 PVD28728.1 - 0.083 13.3 5.1 0.3 11.5 1.6 2.7 1 1 1 2 2 2 0 Latarcin precursor S8_pro-domain PF16470.5 PVD28728.1 - 0.28 12.0 1.2 0.53 11.1 0.2 1.9 2 0 0 2 2 1 0 Peptidase S8 pro-domain DUF1664 PF07889.12 PVD28728.1 - 0.28 11.2 17.0 0.11 12.5 5.4 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) YabA PF06156.13 PVD28728.1 - 0.56 10.9 15.1 2.4 8.8 5.0 3.3 2 1 1 3 3 3 0 Initiation control protein YabA BNIP2 PF12496.8 PVD28728.1 - 0.63 10.5 4.1 26 5.2 0.0 2.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Prefoldin_3 PF13758.6 PVD28728.1 - 0.89 9.6 10.0 1.1 9.3 0.3 3.7 3 1 0 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 PVD28728.1 - 1.1 8.1 21.1 0.14 11.0 10.4 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 PVD28728.1 - 2.3 8.6 22.2 0.77 10.1 6.7 2.8 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 PVD28728.1 - 3 8.0 22.0 0.082 13.0 4.2 4.7 2 1 2 4 4 4 0 TolA binding protein trimerisation UPF0242 PF06785.11 PVD28728.1 - 3.3 7.8 23.0 0.71 9.9 1.8 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 PVD28728.1 - 3.4 7.5 16.3 0.13 12.1 5.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Phage_HK97_TLTM PF06120.11 PVD28728.1 - 3.8 6.6 15.5 0.2 10.8 8.7 2.1 2 0 0 2 2 2 0 Tail length tape measure protein ATG16 PF08614.11 PVD28728.1 - 4 7.6 27.8 2.9 8.1 4.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HMMR_C PF15908.5 PVD28728.1 - 4.3 7.6 11.3 2.6 8.3 2.4 2.9 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal zf-CHY PF05495.12 PVD28728.1 - 6.8 7.3 12.5 0.53 10.8 4.7 3.1 1 1 1 2 2 2 0 CHY zinc finger zf-C3HC4_4 PF15227.6 PVD28728.1 - 7.2 6.9 18.2 6.1 7.1 7.1 3.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING C1q PF00386.21 PVD28729.1 - 5.7e-09 36.3 2.0 3.7e-08 33.6 0.0 2.9 3 0 0 3 3 3 1 C1q domain zf-RING_UBOX PF13445.6 PVD28729.1 - 3.2e-07 30.2 4.1 3.2e-07 30.2 4.1 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28729.1 - 6.5e-06 26.0 4.9 6.5e-06 26.0 4.9 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 PVD28729.1 - 0.0004 20.5 6.9 0.0004 20.5 6.9 3.3 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD28729.1 - 0.00057 19.7 19.5 0.00073 19.4 5.7 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF724 PF05266.14 PVD28729.1 - 0.0028 17.5 3.5 0.0028 17.5 3.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF724) zf-RING_2 PF13639.6 PVD28729.1 - 0.0039 17.5 7.8 0.0039 17.5 7.8 2.9 2 1 0 2 2 2 1 Ring finger domain IBR PF01485.21 PVD28729.1 - 0.0053 17.0 4.6 0.0053 17.0 4.6 3.1 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain DUF2730 PF10805.8 PVD28729.1 - 0.13 12.3 12.3 0.1 12.7 1.7 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) HALZ PF02183.18 PVD28729.1 - 0.18 12.0 5.1 0.29 11.4 1.4 3.2 3 0 0 3 3 2 0 Homeobox associated leucine zipper Latarcin PF10279.9 PVD28729.1 - 0.52 10.8 12.5 0.065 13.7 3.4 3.1 3 0 0 3 3 3 0 Latarcin precursor DUF1664 PF07889.12 PVD28729.1 - 0.89 9.6 21.9 1.2 9.2 3.5 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 PVD28729.1 - 1 9.6 24.8 0.28 11.4 14.3 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 PVD28729.1 - 2 8.5 31.9 3.1 7.8 3.3 3.2 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-CHY PF05495.12 PVD28729.1 - 2.8 8.5 11.8 0.49 10.9 4.8 3.1 1 1 2 3 3 3 0 CHY zinc finger DUF4094 PF13334.6 PVD28729.1 - 3.1 8.3 6.4 0.67 10.4 1.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Eapp_C PF10238.9 PVD28729.1 - 4.4 7.4 12.8 0.039 14.0 1.8 3.1 3 0 0 3 3 3 0 E2F-associated phosphoprotein zf-C3HC4_4 PF15227.6 PVD28729.1 - 5.3 7.3 16.7 14 5.9 8.4 3.6 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING C1q PF00386.21 PVD28730.1 - 1.1e-27 96.7 5.7 1.3e-11 44.8 0.0 4.7 5 0 0 5 5 5 3 C1q domain zf-B_box PF00643.24 PVD28730.1 - 0.00067 19.8 28.3 0.0033 17.5 8.6 3.2 3 0 0 3 3 3 2 B-box zinc finger BclA_C PF18573.1 PVD28730.1 - 0.0016 18.4 1.2 0.29 11.0 0.0 3.5 3 1 0 3 3 3 1 BclA C-terminal domain OCRE PF17780.1 PVD28730.1 - 0.0034 17.4 0.0 11 6.1 0.0 3.5 3 0 0 3 3 3 1 OCRE domain PA14 PF07691.12 PVD28730.1 - 0.034 14.0 0.0 24 4.7 0.0 3.4 3 0 0 3 3 3 0 PA14 domain HALZ PF02183.18 PVD28730.1 - 1.1 9.6 8.3 0.42 10.9 1.1 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lip_prot_lig_C PF10437.9 PVD28730.1 - 1.6 8.8 7.4 2.2 8.3 0.1 3.4 4 1 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus CENP-F_leu_zip PF10473.9 PVD28730.1 - 3.1 7.8 76.4 2 8.4 14.3 6.4 5 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.6 PVD28731.1 - 0.0056 16.9 8.2 0.008 16.4 8.2 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-B_box PF00643.24 PVD28731.1 - 0.012 15.7 16.8 0.012 15.7 16.8 2.6 2 1 0 2 2 2 0 B-box zinc finger COG2 PF06148.11 PVD28731.1 - 0.015 15.3 8.4 0.22 11.6 1.7 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lebercilin PF15619.6 PVD28731.1 - 0.022 14.4 9.5 0.15 11.7 2.7 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-RING_2 PF13639.6 PVD28731.1 - 0.031 14.6 6.0 0.031 14.6 6.0 2.5 2 0 0 2 2 2 0 Ring finger domain SYCE1 PF15233.6 PVD28731.1 - 0.14 12.2 8.8 0.18 11.8 7.3 1.9 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 NPV_P10 PF05531.12 PVD28731.1 - 0.2 12.2 7.8 3.8 8.0 0.5 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PVD28731.1 - 0.31 11.1 7.4 0.68 10.0 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 PVD28731.1 - 0.32 11.0 13.0 0.15 12.1 2.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PVD28731.1 - 0.43 11.0 3.3 13 6.3 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 PVD28731.1 - 0.93 8.9 13.9 1.7 8.0 13.9 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 FlxA PF14282.6 PVD28731.1 - 1.5 8.9 11.5 5.2 7.1 0.8 2.6 1 1 0 2 2 2 0 FlxA-like protein DASH_Dad2 PF08654.10 PVD28731.1 - 5.2 7.6 9.2 1.8 9.0 2.0 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad2 Retrotrans_gag PF03732.17 PVD28732.1 - 0.00016 21.9 0.3 0.00047 20.4 0.1 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 PVD28732.1 - 0.0035 17.4 1.2 0.0035 17.4 1.2 1.8 2 0 0 2 2 2 1 Zinc knuckle C1q PF00386.21 PVD28733.1 - 3e-10 40.4 0.0 6.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 C1q domain zf-B_box PF00643.24 PVD28733.1 - 1e-06 28.8 5.6 2.5e-06 27.5 5.6 1.7 1 0 0 1 1 1 1 B-box zinc finger ADIP PF11559.8 PVD28733.1 - 0.0042 17.2 2.7 0.0042 17.2 2.7 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 PVD28733.1 - 0.0066 16.3 6.4 0.0066 16.3 6.4 2.3 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH EspB_PE PF18625.1 PVD28733.1 - 0.02 15.3 1.5 0.093 13.2 0.3 2.2 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Prefoldin_3 PF13758.6 PVD28733.1 - 0.057 13.5 1.1 0.72 9.9 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 PVD28733.1 - 0.14 12.8 8.4 7.9 7.2 0.1 3.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF2046 PF09755.9 PVD28733.1 - 0.2 10.9 10.5 0.092 12.0 4.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) zf-HIT PF04438.16 PVD28733.1 - 0.21 11.5 6.5 0.3 11.0 4.0 2.3 2 0 0 2 2 2 0 HIT zinc finger Leu_zip PF15294.6 PVD28733.1 - 0.4 10.2 10.9 0.19 11.2 6.5 2.0 2 0 0 2 2 2 0 Leucine zipper HALZ PF02183.18 PVD28733.1 - 0.6 10.4 3.7 0.46 10.7 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4795 PF16043.5 PVD28733.1 - 0.86 9.2 14.0 0.21 11.2 7.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ZapB PF06005.12 PVD28733.1 - 0.86 10.1 8.6 1.1 9.7 3.5 2.9 2 1 0 2 2 2 0 Cell division protein ZapB SYCE1 PF15233.6 PVD28733.1 - 0.92 9.6 9.5 0.19 11.8 0.3 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 CENP-F_leu_zip PF10473.9 PVD28733.1 - 0.94 9.5 11.3 0.2 11.7 0.3 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_C PF15908.5 PVD28733.1 - 1.3 9.3 9.5 1.1 9.6 0.7 2.9 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal PRKG1_interact PF15898.5 PVD28733.1 - 1.9 9.4 8.6 5.5 8.0 0.1 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF334 PF03904.13 PVD28733.1 - 2.6 7.5 7.6 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF4140 PF13600.6 PVD28733.1 - 2.9 8.4 6.4 12 6.5 0.9 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lectin_N PF03954.14 PVD28733.1 - 3.1 7.6 8.0 0.93 9.2 4.6 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Tnp_zf-ribbon_2 PF13842.6 PVD28733.1 - 6 7.8 7.7 18 6.2 7.7 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon FlaC_arch PF05377.11 PVD28733.1 - 8.3 6.9 6.4 53 4.3 2.4 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) C1q PF00386.21 PVD28734.1 - 2.1e-07 31.2 0.0 7.1e-07 29.5 0.0 1.9 2 0 0 2 2 1 1 C1q domain zf-B_box PF00643.24 PVD28734.1 - 0.0011 19.1 10.6 0.0011 19.1 10.6 2.1 2 0 0 2 2 2 1 B-box zinc finger TPR_MLP1_2 PF07926.12 PVD28734.1 - 0.0021 18.1 1.1 0.0021 18.1 1.1 3.2 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 PVD28734.1 - 0.0097 15.5 12.4 0.0097 15.5 12.4 2.6 2 1 1 3 3 3 1 Leucine zipper CENP-Q PF13094.6 PVD28734.1 - 0.029 14.6 13.7 0.84 9.8 5.9 2.8 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.9 PVD28734.1 - 0.1 12.6 20.8 1.3 9.0 1.2 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Collagen_mid PF15984.5 PVD28734.1 - 0.13 12.0 0.5 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial collagen, middle region IBR PF01485.21 PVD28734.1 - 0.13 12.5 9.3 0.52 10.6 9.3 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ribonuc_2-5A PF06479.12 PVD28734.1 - 0.15 12.2 1.1 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease 2-5A WD40_alt PF14077.6 PVD28734.1 - 0.18 11.7 1.9 4.3 7.3 0.1 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif Filament PF00038.21 PVD28734.1 - 0.18 11.3 14.1 0.063 12.8 4.6 2.1 2 0 0 2 2 2 0 Intermediate filament protein HMMR_C PF15908.5 PVD28734.1 - 0.23 11.7 6.3 0.7 10.1 6.3 1.8 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Spc7 PF08317.11 PVD28734.1 - 2.5 6.9 17.6 0.56 9.0 9.8 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein zf-HIT PF04438.16 PVD28734.1 - 3 7.8 19.4 0.49 10.3 12.0 3.1 2 1 0 2 2 2 0 HIT zinc finger Cnn_1N PF07989.11 PVD28734.1 - 4.6 7.5 13.1 1.2 9.3 4.2 3.4 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 PVD28734.1 - 6.8 6.9 18.8 4.1 7.6 3.9 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 PVD28734.1 - 7.7 7.3 7.3 3.5 8.4 0.6 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) PARP PF00644.20 PVD28735.1 - 6.1e-22 78.2 2.7 1.5e-20 73.7 2.7 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD28735.1 - 1.8e-12 47.3 0.1 8.5e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 Macro domain WWE PF02825.20 PVD28735.1 - 6.6e-05 23.4 0.2 0.00022 21.8 0.2 2.0 1 0 0 1 1 1 1 WWE domain YqgF PF14639.6 PVD28735.1 - 0.49 10.2 2.8 5.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 SLS PF14611.6 PVD28735.1 - 2.2 8.0 8.7 1.6 8.5 3.9 2.9 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Sulfatase PF00884.23 PVD28736.1 - 0.00067 19.1 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4371 PF14291.6 PVD28737.1 - 0.00017 21.3 0.1 0.00029 20.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HTH_11 PF08279.12 PVD28737.1 - 0.14 12.1 0.2 0.38 10.7 0.2 1.7 1 0 0 1 1 1 0 HTH domain C1q PF00386.21 PVD28738.1 - 1.2e-12 48.1 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 C1q domain zf-RING_UBOX PF13445.6 PVD28738.1 - 1e-05 25.5 7.3 1e-05 25.5 7.3 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28738.1 - 5e-05 23.2 6.4 5e-05 23.2 6.4 4.0 3 2 0 4 4 4 1 zinc-RING finger domain Img2 PF05046.14 PVD28738.1 - 0.00064 20.0 0.7 0.024 14.9 0.1 2.9 1 1 2 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) zf-B_box PF00643.24 PVD28738.1 - 0.0011 19.0 9.4 0.0011 19.0 9.4 4.4 5 0 0 5 5 4 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD28738.1 - 0.0022 17.9 6.5 0.0022 17.9 6.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD28738.1 - 0.0026 18.0 7.0 0.0026 18.0 7.0 3.8 4 1 0 4 4 3 1 Ring finger domain CorA PF01544.18 PVD28738.1 - 0.014 14.8 11.6 0.084 12.2 0.8 3.0 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PVD28738.1 - 0.051 13.6 9.7 2.3 8.2 2.4 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4286 PF14114.6 PVD28738.1 - 0.056 13.9 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Prefoldin_3 PF13758.6 PVD28738.1 - 0.12 12.5 3.1 2.4 8.2 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit Apolipoprotein PF01442.18 PVD28738.1 - 0.24 11.3 17.9 0.72 9.7 8.0 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.11 PVD28738.1 - 0.44 10.4 16.5 0.4 10.5 0.3 3.5 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) OmpH PF03938.14 PVD28738.1 - 0.73 10.2 17.4 15 5.9 5.7 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Plasmid_RAQPRD PF09686.10 PVD28738.1 - 2 8.7 6.0 6.3 7.1 0.1 3.7 3 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) C1_2 PF03107.16 PVD28738.1 - 4.3 7.7 17.6 0.13 12.6 7.0 3.4 3 0 0 3 3 3 0 C1 domain ZapB PF06005.12 PVD28738.1 - 5.8 7.4 13.9 0.94 10.0 0.2 3.5 3 1 0 3 3 3 0 Cell division protein ZapB Muted PF14942.6 PVD28738.1 - 8.3 6.7 16.1 3 8.2 1.2 3.1 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein C1q PF00386.21 PVD28739.1 - 3.3e-10 40.2 0.0 7.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 C1q domain zf-RING_UBOX PF13445.6 PVD28739.1 - 1.1e-06 28.6 9.5 1.1e-06 28.6 9.5 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD28739.1 - 8e-06 25.7 8.3 8e-06 25.7 8.3 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 PVD28739.1 - 0.00062 19.9 8.7 0.00062 19.9 8.7 3.7 5 0 0 5 5 2 1 B-box zinc finger zf-RING_2 PF13639.6 PVD28739.1 - 0.0007 19.9 23.9 0.001 19.3 10.0 3.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PVD28739.1 - 0.00091 19.0 7.0 0.00091 19.0 7.0 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prefoldin_3 PF13758.6 PVD28739.1 - 0.00096 19.2 2.1 0.061 13.4 0.3 2.9 2 1 0 2 2 2 1 Prefoldin subunit Lectin_N PF03954.14 PVD28739.1 - 0.0014 18.4 3.1 0.0014 18.4 3.1 3.8 4 1 0 4 4 4 1 Hepatic lectin, N-terminal domain Lant_dehydr_C PF14028.6 PVD28739.1 - 0.0014 18.3 1.1 0.0025 17.4 1.1 1.3 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term Focal_AT PF03623.13 PVD28739.1 - 0.007 16.4 3.9 0.007 16.4 3.9 2.9 2 1 1 3 3 3 1 Focal adhesion targeting region zf-RING_11 PF17123.5 PVD28739.1 - 0.012 15.4 4.2 0.022 14.5 2.7 2.5 2 0 0 2 2 2 0 RING-like zinc finger PUB PF09409.10 PVD28739.1 - 0.018 14.9 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 PUB domain Img2 PF05046.14 PVD28739.1 - 0.02 15.2 0.1 0.075 13.3 0.1 1.9 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) zf-C3HC4_2 PF13923.6 PVD28739.1 - 0.02 14.7 4.7 0.02 14.7 4.7 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.16 PVD28739.1 - 0.033 14.0 16.2 0.024 14.5 6.7 3.6 3 0 0 3 3 3 0 HIT zinc finger Baculo_PEP_C PF04513.12 PVD28739.1 - 0.067 13.2 10.7 0.7 9.9 2.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus dCache_1 PF02743.18 PVD28739.1 - 0.18 11.6 1.2 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Cache domain YabA PF06156.13 PVD28739.1 - 0.27 11.9 15.3 2.9 8.6 2.7 3.5 2 1 1 3 3 3 0 Initiation control protein YabA C1_2 PF03107.16 PVD28739.1 - 0.97 9.8 20.3 0.12 12.7 6.6 3.7 2 1 1 3 3 3 0 C1 domain YhfH PF14149.6 PVD28739.1 - 1.1 9.2 7.9 2e+02 2.1 7.9 3.2 1 1 0 1 1 1 0 YhfH-like protein zf-C3HC4_4 PF15227.6 PVD28739.1 - 1.8 8.8 17.6 4 7.7 9.2 3.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING HDAC4_Gln PF12203.8 PVD28739.1 - 2 8.6 8.4 0.4 10.9 3.6 2.3 2 0 0 2 2 1 0 Glutamine rich N terminal domain of histone deacetylase 4 FlaC_arch PF05377.11 PVD28739.1 - 2.2 8.7 10.5 7.4 7.1 0.7 4.1 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HypA PF01155.19 PVD28739.1 - 2.6 8.1 14.7 0.62 10.1 0.9 3.6 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OmpH PF03938.14 PVD28739.1 - 3.5 8.0 15.8 9 6.6 2.5 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3037 PF11236.8 PVD28739.1 - 3.8 7.9 7.7 3.6 8.0 0.1 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3037) CorA PF01544.18 PVD28739.1 - 4.6 6.5 13.9 2.5 7.3 1.4 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein zinc_ribbon_10 PF10058.9 PVD28739.1 - 5.1 6.9 8.7 19 5.0 0.1 3.8 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NPV_P10 PF05531.12 PVD28739.1 - 5.1 7.6 14.7 22 5.6 0.1 4.2 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Cnn_1N PF07989.11 PVD28739.1 - 6.7 7.0 14.5 1.4 9.1 1.7 3.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Muted PF14942.6 PVD28739.1 - 9.6 6.5 20.0 0.93 9.8 5.5 2.7 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein ApoL PF05461.11 PVD28740.1 - 5.5e-12 45.6 14.5 2.3e-06 27.2 0.2 3.4 1 1 1 3 3 3 3 Apolipoprotein L DUF334 PF03904.13 PVD28740.1 - 0.011 15.3 0.1 0.033 13.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF4709 PF15821.5 PVD28740.1 - 0.032 14.5 3.9 0.39 11.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) AAA_15 PF13175.6 PVD28740.1 - 0.034 13.9 0.4 0.059 13.1 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF2207 PF09972.9 PVD28740.1 - 0.036 12.8 2.2 0.29 9.9 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) SseC PF04888.12 PVD28740.1 - 0.28 10.7 24.7 0.71 9.4 12.3 3.1 2 1 1 3 3 3 0 Secretion system effector C (SseC) like family Ldl_recept_a PF00057.18 PVD28741.1 - 1.8e-12 47.2 34.3 1.3e-05 25.2 0.6 4.2 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD28741.1 - 0.0016 19.1 1.9 0.0037 18.0 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain DIOX_N PF14226.6 PVD28742.1 - 1.5e-19 70.8 0.0 4.3e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PVD28742.1 - 3.9e-13 49.8 0.0 2e-12 47.5 0.0 2.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAH PF02671.21 PVD28742.1 - 5.3e-09 36.1 0.0 5.5 7.2 0.0 5.6 4 0 0 4 4 4 4 Paired amphipathic helix repeat TAD2 PF18521.1 PVD28742.1 - 3e-05 23.7 6.4 14 5.8 0.1 4.8 4 0 0 4 4 4 0 Transactivation domain 2 Myosin-VI_CBD PF16521.5 PVD28742.1 - 0.00092 19.2 0.3 20 5.2 0.0 3.7 3 0 0 3 3 3 0 Myosin VI cargo binding domain MIF4G_like_2 PF09090.11 PVD28742.1 - 0.0022 17.5 1.6 22 4.4 0.0 4.7 5 0 0 5 5 5 0 MIF4G like UPF0370 PF13980.6 PVD28742.1 - 0.0034 17.4 0.1 28 4.8 0.0 3.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) HEAT PF02985.22 PVD28742.1 - 0.014 15.6 0.0 1.3e+02 3.2 0.0 5.2 4 0 0 4 4 4 0 HEAT repeat V-ATPase_H_C PF11698.8 PVD28742.1 - 0.014 15.5 0.7 4.2 7.5 0.1 4.1 2 0 0 2 2 2 0 V-ATPase subunit H PAD_M PF08527.10 PVD28742.1 - 0.028 14.1 6.9 22 4.7 0.1 4.5 4 0 0 4 4 4 0 Protein-arginine deiminase (PAD) middle domain HEAT_2 PF13646.6 PVD28742.1 - 0.033 14.6 11.1 44 4.6 0.1 5.8 5 0 0 5 5 5 0 HEAT repeats Ribosomal_S21 PF01165.20 PVD28742.1 - 0.06 13.1 1.9 60 3.5 0.0 4.2 4 0 0 4 4 4 0 Ribosomal protein S21 DUF4071 PF13281.6 PVD28742.1 - 0.15 11.1 17.1 3.5 6.6 0.3 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4071) Creb_binding PF09030.10 PVD28742.1 - 0.19 12.4 11.4 37 5.1 0.2 4.5 4 0 0 4 4 4 0 Creb binding INSC_LBD PF16748.5 PVD28742.1 - 0.23 10.9 13.8 29 4.2 0.0 5.8 6 0 0 6 6 6 0 Inscuteable LGN-binding domain MethyTransf_Reg PF10119.9 PVD28742.1 - 0.49 11.1 6.1 1.8e+02 3.0 0.1 5.7 6 0 0 6 6 5 0 Predicted methyltransferase regulatory domain MMS19_N PF14500.6 PVD28742.1 - 5.7 6.4 27.0 8.6 5.9 1.1 6.3 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II PAH PF02671.21 PVD28743.1 - 0.00065 19.8 0.1 2.5 8.3 0.0 3.2 2 0 0 2 2 2 2 Paired amphipathic helix repeat TAD2 PF18521.1 PVD28743.1 - 0.0097 15.8 0.9 6.1 7.0 0.1 2.9 2 0 0 2 2 2 2 Transactivation domain 2 Goodbye PF17109.5 PVD28743.1 - 0.015 15.7 0.1 13 6.3 0.0 3.4 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain HEAT_2 PF13646.6 PVD28743.1 - 0.25 11.8 2.1 36 4.8 0.1 3.4 2 0 0 2 2 2 0 HEAT repeats MMS19_N PF14500.6 PVD28743.1 - 2.3 7.7 15.5 6 6.4 1.1 4.1 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II MethyTransf_Reg PF10119.9 PVD28743.1 - 2.6 8.8 4.6 73 4.2 0.1 4.7 5 0 0 5 5 5 0 Predicted methyltransferase regulatory domain Creb_binding PF09030.10 PVD28743.1 - 2.6 8.7 4.4 33 5.2 0.2 2.8 3 0 0 3 3 3 0 Creb binding DUF4071 PF13281.6 PVD28743.1 - 3.5 6.6 7.4 6.6 5.7 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4071) HLH PF00010.26 PVD28744.1 - 3.5e-17 62.1 3.4 8.6e-17 60.8 3.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_Tnp_4 PF13359.6 PVD28746.1 - 4.9e-18 65.3 0.0 6.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 PVD28746.1 - 0.00057 19.5 0.0 0.00077 19.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 PVD28746.1 - 0.058 13.0 0.2 0.27 10.9 0.2 1.9 1 1 0 1 1 1 0 Transposase DDE domain RMI1_N PF08585.12 PVD28747.1 - 2.5e-48 164.7 3.4 4.4e-47 160.6 0.0 2.7 2 0 0 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 PVD28747.1 - 1.4e-27 96.3 0.4 4.1e-27 94.8 0.4 1.8 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold HbrB PF08539.11 PVD28748.1 - 4e-12 46.4 1.8 3.1e-10 40.3 0.1 2.3 1 1 1 2 2 2 2 HbrB-like DUF4699 PF15770.5 PVD28749.1 - 0.049 13.4 0.4 0.052 13.3 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Arm PF00514.23 PVD28750.1 - 0.0011 19.0 12.2 0.39 10.8 0.3 6.1 6 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PVD28750.1 - 9.3 6.9 13.0 53 4.5 1.6 5.3 5 1 1 6 6 6 0 HEAT-like repeat SVIP PF15811.5 PVD28751.1 - 5e-27 94.2 4.4 5.5e-27 94.0 4.4 1.0 1 0 0 1 1 1 1 Small VCP/p97-interacting protein DUF3295 PF11702.8 PVD28751.1 - 0.002 17.6 0.2 0.0024 17.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) U79_P34 PF03064.16 PVD28751.1 - 0.062 12.6 3.4 0.066 12.6 3.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TAL_FSA PF00923.19 PVD28752.1 - 3.2e-88 295.8 0.2 3.7e-88 295.6 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FYVE PF01363.21 PVD28753.1 - 0.039 14.1 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 FYVE zinc finger Phospholip_A2_1 PF00068.19 PVD28755.1 - 1.8e-19 70.2 17.8 2.8e-19 69.6 17.8 1.2 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 PVD28755.1 - 0.0017 18.6 15.7 0.19 12.0 9.0 2.6 1 1 1 2 2 2 2 Phospholipase A2 LURAP PF14854.6 PVD28758.1 - 3.2e-05 23.8 0.3 3.2e-05 23.8 0.3 1.8 2 0 0 2 2 2 1 Leucine rich adaptor protein DUF4530 PF15039.6 PVD28758.1 - 0.0064 16.6 0.2 0.014 15.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) FAM167 PF11652.8 PVD28758.1 - 0.027 14.9 2.2 0.067 13.7 2.2 1.6 1 0 0 1 1 1 0 FAM167 DUF3035 PF11233.8 PVD28758.1 - 0.18 12.1 0.7 0.33 11.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Macoilin PF09726.9 PVD28758.1 - 0.19 10.3 1.0 0.26 9.8 1.0 1.1 1 0 0 1 1 1 0 Macoilin family CUB PF00431.20 PVD28760.1 - 2.9e-67 223.9 6.6 8e-20 71.2 0.0 4.3 4 0 0 4 4 4 4 CUB domain Phytochelatin PF05023.14 PVD28762.1 - 7.5e-88 293.3 0.0 3.1e-87 291.3 0.0 1.9 2 0 0 2 2 2 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 PVD28762.1 - 0.049 14.2 0.0 0.51 10.9 0.0 2.2 1 1 0 1 1 1 0 Peptidase_C39 like family CRIC_ras_sig PF10534.9 PVD28763.1 - 3.9e-21 75.0 0.3 1.1e-20 73.6 0.3 1.9 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras PH PF00169.29 PVD28763.1 - 4e-15 56.2 2.0 8.2e-15 55.2 0.5 2.3 2 0 0 2 2 2 1 PH domain SAM_1 PF00536.30 PVD28763.1 - 6.5e-12 45.7 2.0 7.2e-12 45.6 0.1 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD28763.1 - 6.6e-12 45.4 0.1 2e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 PVD28763.1 - 5.4e-11 42.7 0.2 1.3e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD28763.1 - 2.3e-10 40.2 0.0 5.8e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 PVD28763.1 - 0.00017 22.0 5.6 0.00075 19.9 5.6 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PDZ_2 PF13180.6 PVD28763.1 - 0.0044 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SAM_PNT PF02198.16 PVD28763.1 - 0.046 13.7 0.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain adh_short_C2 PF13561.6 PVD28764.1 - 1.7e-40 139.0 0.2 1.1e-26 93.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD28764.1 - 2.9e-35 121.5 0.2 3.8e-35 121.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD28764.1 - 6.6e-09 35.9 0.1 1e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 KR domain ATP-gua_Ptrans PF00217.19 PVD28765.1 - 3.4e-83 278.3 0.0 4.5e-83 277.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 PVD28765.1 - 9.4e-26 90.0 0.0 1.9e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.19 PVD28766.1 - 3.5e-254 837.0 3.8 1.5e-83 279.5 0.0 5.9 5 1 0 5 5 5 5 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 PVD28766.1 - 1.6e-112 368.0 0.8 1.3e-28 99.2 0.0 4.5 4 0 0 4 4 4 4 ATP:guanido phosphotransferase, N-terminal domain TEX33 PF15400.6 PVD28766.1 - 0.00074 20.0 1.1 5.4 7.5 0.0 4.2 4 0 0 4 4 4 2 Testis-expressed sequence 33 protein family PsbK PF02533.15 PVD28766.1 - 0.0078 16.3 11.3 0.67 10.1 0.1 4.0 4 0 0 4 4 4 2 Photosystem II 4 kDa reaction centre component NOD PF06816.13 PVD28766.1 - 0.066 12.8 2.2 1.4e+02 2.2 0.0 4.8 5 0 0 5 5 5 0 NOTCH protein TB PF00683.17 PVD28766.1 - 0.075 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 TB domain SIR4_SID PF16991.5 PVD28766.1 - 0.11 12.5 7.4 4.4 7.3 0.1 3.5 4 0 0 4 4 4 0 Sir4 SID domain DUF3158 PF11358.8 PVD28766.1 - 0.62 9.8 3.6 22 4.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3158) DUF3886 PF13025.6 PVD28766.1 - 8.7 6.6 15.1 0.6 10.3 0.4 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3886) LRR_8 PF13855.6 PVD28767.1 - 3.7e-10 39.4 1.7 2.1e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat Ldl_recept_a PF00057.18 PVD28767.1 - 2e-09 37.5 31.5 2.4e-06 27.6 0.6 4.7 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A LRR_4 PF12799.7 PVD28767.1 - 5.7e-05 23.4 0.2 0.18 12.3 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 PVD28767.1 - 0.00072 20.3 1.8 0.0024 18.6 1.8 2.0 1 1 0 1 1 1 1 Lectin C-type domain CUB_2 PF02408.20 PVD28767.1 - 0.0052 16.6 1.5 0.18 11.6 1.4 2.6 2 0 0 2 2 2 1 CUB-like domain LRR_9 PF14580.6 PVD28767.1 - 0.16 11.4 0.2 0.35 10.3 0.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeat zf-C3HC4_3 PF13920.6 PVD28768.1 - 2.8e-12 46.3 12.6 4e-12 45.8 12.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD28768.1 - 0.00096 19.0 12.4 0.0016 18.2 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 PVD28768.1 - 0.016 15.5 6.8 0.031 14.6 6.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 PVD28768.1 - 1 9.4 15.0 3.2 7.8 15.1 1.7 1 1 1 2 2 2 0 zinc-RING finger domain BIR PF00653.21 PVD28769.1 - 2.5e-09 37.6 0.0 6.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain SPG48 PF14764.6 PVD28769.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking BIR PF00653.21 PVD28770.1 - 3.4e-10 40.4 1.9 5.2e-10 39.8 1.9 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.21 PVD28771.1 - 3.2e-10 40.5 0.3 5.8e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain MAGI_u1 PF16663.5 PVD28771.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI BIR PF00653.21 PVD28772.1 - 9.5e-25 87.1 4.6 2.4e-19 69.7 0.2 2.8 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain Cucumo_2B PF03263.13 PVD28772.1 - 0.058 13.9 2.7 8.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Cucumovirus protein 2B RNA_pol_N PF01194.17 PVD28772.1 - 0.19 12.0 3.5 9.5 6.6 0.3 3.1 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit CCDC-167 PF15188.6 PVD28772.1 - 0.9 9.9 3.4 0.53 10.7 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-C3HC4_3 PF13920.6 PVD28773.1 - 2.5e-07 30.4 8.3 2.5e-07 30.4 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 PVD28773.1 - 3e-05 24.6 9.5 0.0098 16.5 0.1 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain Prok-RING_4 PF14447.6 PVD28773.1 - 0.017 15.0 7.3 0.037 13.9 7.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PRKG1_interact PF15898.5 PVD28773.1 - 0.092 13.7 1.8 0.2 12.6 1.8 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain STAT1_TAZ2bind PF12162.8 PVD28773.1 - 0.11 12.1 1.2 0.31 10.7 1.2 1.8 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain zf-RING_5 PF14634.6 PVD28773.1 - 3.5 7.7 9.9 9.4 6.3 9.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain BIR PF00653.21 PVD28774.1 - 1e-28 99.7 12.3 9.1e-19 67.9 0.3 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD28774.1 - 2.7e-07 30.3 8.4 2.7e-07 30.3 8.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1421 PF07223.11 PVD28774.1 - 0.002 17.9 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain (DUF1421) Prok-RING_4 PF14447.6 PVD28774.1 - 0.87 9.5 13.7 0.028 14.3 7.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Tcp11 PF05794.13 PVD28775.1 - 2.2e-101 340.2 7.2 2.5e-101 339.9 7.2 1.0 1 0 0 1 1 1 1 T-complex protein 11 Nucleolin_bd PF16725.5 PVD28775.1 - 0.05 13.3 0.2 0.19 11.4 0.2 1.9 1 0 0 1 1 1 0 Nucleolin binding domain DEP PF00610.21 PVD28776.1 - 3.5e-15 55.8 1.2 5.1e-14 52.1 0.1 2.9 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF148 PF02520.17 PVD28776.1 - 0.035 14.2 0.1 0.13 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF148 Ion_trans PF00520.31 PVD28777.1 - 3.5e-53 180.3 53.3 6.8e-28 97.5 29.0 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PVD28777.1 - 0.12 11.0 53.1 0.0049 15.6 21.0 5.9 2 2 0 2 2 2 0 Polycystin cation channel Presenilin PF01080.17 PVD28779.1 - 1.3 7.7 3.1 2.4 6.8 3.1 1.4 1 0 0 1 1 1 0 Presenilin zf-B_box PF00643.24 PVD28782.1 - 0.018 15.2 0.4 0.04 14.1 0.4 1.6 1 0 0 1 1 1 0 B-box zinc finger zf-B_box PF00643.24 PVD28783.1 - 0.0069 16.5 0.2 0.014 15.5 0.2 1.5 1 0 0 1 1 1 1 B-box zinc finger WAP PF00095.21 PVD28784.1 - 5e-13 49.2 33.6 5.1e-08 33.2 12.2 4.5 6 0 0 6 6 6 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF4432 PF14486.6 PVD28784.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) RhoGEF PF00621.20 PVD28786.1 - 5.4e-05 23.5 0.1 9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 PVD28787.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 PH domain RA PF00788.23 PVD28787.1 - 0.09 13.4 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PH PF00169.29 PVD28787.1 - 0.14 12.6 0.2 0.36 11.4 0.2 1.7 1 1 0 1 1 1 0 PH domain RhoGAP PF00620.27 PVD28789.1 - 2.2e-29 102.2 0.4 4.3e-29 101.3 0.4 1.4 1 0 0 1 1 1 1 RhoGAP domain Cystatin PF00031.21 PVD28793.1 - 1.7e-14 53.8 0.0 1.9e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 PVD28793.1 - 0.015 15.6 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Gal-bind_lectin PF00337.22 PVD28794.1 - 1.1e-09 37.9 0.0 3.7e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 PVD28795.1 - 3.9e-08 32.9 0.0 7.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Galactoside-binding lectin ApoL PF05461.11 PVD28796.1 - 1.9e-07 30.7 1.7 2.9e-07 30.1 1.7 1.2 1 0 0 1 1 1 1 Apolipoprotein L Gal-bind_lectin PF00337.22 PVD28796.1 - 0.00076 19.0 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 Galactoside-binding lectin TraT PF05818.12 PVD28796.1 - 2.9 7.5 4.7 0.74 9.5 0.2 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein ApoL PF05461.11 PVD28797.1 - 4e-20 72.4 16.0 5.3e-12 45.7 1.8 2.4 2 1 0 2 2 2 2 Apolipoprotein L DUF2207 PF09972.9 PVD28797.1 - 0.014 14.2 0.3 2.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ApoL PF05461.11 PVD28798.1 - 6e-09 35.7 2.6 1.2e-08 34.7 2.6 1.4 1 1 0 1 1 1 1 Apolipoprotein L SseC PF04888.12 PVD28798.1 - 1.8 8.1 16.7 2.4 7.7 15.5 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Cystatin PF00031.21 PVD28799.1 - 1.3e-12 47.8 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ApoL PF05461.11 PVD28800.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein L DUF3040 PF11239.8 PVD28800.1 - 0.0011 19.2 5.8 0.16 12.2 0.7 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3040) Trp_oprn_chp PF09534.10 PVD28800.1 - 0.0021 17.9 5.1 0.0038 17.0 5.1 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2721 PF11026.8 PVD28800.1 - 0.0072 16.2 0.6 0.66 9.9 0.2 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2721) DUF2207 PF09972.9 PVD28800.1 - 0.011 14.5 0.0 0.026 13.3 0.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SseC PF04888.12 PVD28800.1 - 0.028 14.0 0.1 0.028 14.0 0.1 2.1 1 1 0 2 2 2 0 Secretion system effector C (SseC) like family C1q PF00386.21 PVD28801.1 - 9.4e-11 42.0 0.0 2.5e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 C1q domain APG6_N PF17675.1 PVD28801.1 - 0.016 15.8 1.6 0.016 15.8 1.6 4.8 2 1 1 3 3 2 0 Apg6 coiled-coil region DUF3509 PF12021.8 PVD28801.1 - 0.059 13.1 4.8 15 5.4 0.5 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3509) Apolipoprotein PF01442.18 PVD28801.1 - 0.12 12.3 32.8 0.54 10.1 11.6 4.2 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 PVD28801.1 - 0.12 12.7 31.3 1.2 9.6 0.6 8.0 5 1 4 9 9 8 0 Flagella accessory protein C (FlaC) Filament PF00038.21 PVD28801.1 - 0.23 11.0 45.0 0.16 11.5 0.6 3.6 2 1 1 3 3 3 0 Intermediate filament protein DUF4327 PF14217.6 PVD28801.1 - 0.35 11.1 7.1 39 4.5 0.1 4.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4327) Myosin_tail_1 PF01576.19 PVD28801.1 - 0.77 7.5 46.9 0.16 9.8 31.3 2.7 2 1 0 2 2 2 0 Myosin tail YabA PF06156.13 PVD28801.1 - 0.79 10.4 40.5 0.12 13.0 2.2 6.9 3 1 4 7 7 7 0 Initiation control protein YabA Pro_sub2 PF18513.1 PVD28801.1 - 1.8 8.8 10.4 6.2 7.1 0.4 3.5 3 1 1 4 4 4 0 Prodomain subtilisin 2 COG2 PF06148.11 PVD28801.1 - 2.1 8.5 29.5 3.4 7.8 2.6 6.4 3 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 HsbA PF12296.8 PVD28801.1 - 2.9 8.3 7.7 2.6 8.5 0.0 4.2 4 1 1 5 5 5 0 Hydrophobic surface binding protein A CENP-F_leu_zip PF10473.9 PVD28801.1 - 6.4 6.8 45.8 0.28 11.2 3.7 5.5 3 1 2 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SseC PF04888.12 PVD28802.1 - 0.0048 16.5 1.2 0.0048 16.5 1.2 6.7 7 2 0 7 7 7 2 Secretion system effector C (SseC) like family Herpes_US9 PF06072.11 PVD28802.1 - 0.054 13.4 0.1 0.22 11.4 0.1 2.1 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2207 PF09972.9 PVD28802.1 - 0.064 12.0 18.7 0.51 9.0 0.1 4.6 3 2 2 5 5 5 0 Predicted membrane protein (DUF2207) UPF0767 PF15990.5 PVD28802.1 - 0.15 12.2 2.1 37 4.6 0.0 3.6 3 0 0 3 3 3 0 UPF0767 family Baculo_PEP_C PF04513.12 PVD28802.1 - 0.29 11.2 12.3 0.86 9.6 0.6 5.0 5 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhaP_Bmeg PF09602.10 PVD28802.1 - 0.38 10.7 17.4 0.38 10.7 0.2 4.3 4 1 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) GldM_N PF12081.8 PVD28802.1 - 0.77 9.8 6.4 2.2 8.3 6.4 1.8 1 0 0 1 1 1 0 GldM N-terminal domain MCU PF04678.13 PVD28802.1 - 0.96 9.5 3.9 15 5.7 0.0 3.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DASH_Dad2 PF08654.10 PVD28802.1 - 1.1 9.8 9.1 2.9 8.4 1.3 3.8 2 1 0 3 3 3 0 DASH complex subunit Dad2 Baculo_p24 PF05073.12 PVD28802.1 - 1.6 8.5 10.2 1.9 8.3 0.2 3.3 3 0 0 3 3 3 0 Baculovirus P24 capsid protein Hemerythrin PF01814.23 PVD28802.1 - 3.5 8.3 6.8 42 4.8 0.0 4.0 4 0 0 4 4 3 0 Hemerythrin HHE cation binding domain Anoctamin PF04547.12 PVD28803.1 - 2e-105 353.3 8.7 2.8e-59 201.2 0.0 2.3 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 PVD28803.1 - 1.2e-61 208.3 1.7 1.9e-61 207.7 1.7 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF1179 PF06678.11 PVD28804.1 - 0.048 13.6 0.1 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) C2 PF00168.30 PVD28805.1 - 4.5e-53 177.9 0.2 2.3e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD28805.1 - 8.3e-05 22.2 0.0 0.065 12.8 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain DUF4982 PF16355.5 PVD28805.1 - 0.03 14.3 0.5 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4982) PTEN_C2 PF10409.9 PVD28805.1 - 0.044 13.5 1.4 3.9 7.2 0.0 2.9 2 1 1 3 3 3 0 C2 domain of PTEN tumour-suppressor protein Tenui_NS4 PF03300.13 PVD28805.1 - 0.048 13.1 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 Transglut_C PF00927.22 PVD28805.1 - 0.11 12.6 0.3 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain EB PF01683.18 PVD28806.1 - 9.4e-05 22.6 2.3 9.4e-05 22.6 2.3 2.5 2 0 0 2 2 2 1 EB module TIL PF01826.17 PVD28806.1 - 0.017 15.3 2.2 0.017 15.3 2.2 2.6 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain hEGF PF12661.7 PVD28806.1 - 0.039 14.6 0.5 0.039 14.6 0.5 3.4 3 0 0 3 3 3 0 Human growth factor-like EGF Hid1 PF12722.7 PVD28806.1 - 0.19 9.8 4.3 0.23 9.5 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.6 PVD28808.1 - 9.1 6.7 7.7 19 5.7 7.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-B_box PF00643.24 PVD28809.1 - 1.3e-09 38.0 3.1 1.3e-09 38.0 3.1 2.6 2 0 0 2 2 2 1 B-box zinc finger Reg_prop PF07494.11 PVD28809.1 - 0.071 13.4 0.0 0.32 11.3 0.0 2.2 1 0 0 1 1 1 0 Two component regulator propeller MutH PF02976.15 PVD28809.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH NHL PF01436.21 PVD28809.1 - 0.15 12.1 0.1 1 9.5 0.0 2.5 2 0 0 2 2 2 0 NHL repeat Apolipoprotein PF01442.18 PVD28809.1 - 0.27 11.1 4.8 0.48 10.3 4.8 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4515 PF14988.6 PVD28809.1 - 3.9 7.3 7.9 0.57 10.0 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Calponin PF00402.18 PVD28811.1 - 1.6e-12 46.8 4.2 2.5e-12 46.2 4.2 1.3 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 PVD28811.1 - 4.9e-11 42.8 0.0 8.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Methyltrn_RNA_3 PF02598.17 PVD28812.1 - 1.3e-93 313.6 0.0 2.6e-93 312.7 0.0 1.4 2 0 0 2 2 2 1 Putative RNA methyltransferase Connexin PF00029.19 PVD28812.1 - 0.043 13.6 0.6 0.074 12.8 0.6 1.3 1 0 0 1 1 1 0 Connexin DUF5548 PF17702.1 PVD28812.1 - 0.12 12.1 0.6 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5548) EMC3_TMCO1 PF01956.16 PVD28812.1 - 2.8 7.6 4.7 4.5 7.0 4.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like VWA_2 PF13519.6 PVD28813.1 - 0.0011 19.6 0.4 0.0011 19.6 0.4 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain DDRGK PF09756.9 PVD28814.1 - 0.5 9.9 9.3 1.7 8.2 9.3 1.9 1 0 0 1 1 1 0 DDRGK domain AAA_5 PF07728.14 PVD28815.1 - 3.8e-10 39.9 0.0 2.7e-09 37.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 PVD28815.1 - 8.8e-07 29.0 0.0 5.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Methyltransf_23 PF13489.6 PVD28815.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bap31_Bap29_C PF18035.1 PVD28815.1 - 0.38 10.8 1.9 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain 7tm_1 PF00001.21 PVD28816.1 - 2.3e-06 27.2 20.2 9.2e-06 25.2 4.7 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.6 PVD28816.1 - 3.7 7.9 7.1 0.51 10.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) AAA_5 PF07728.14 PVD28817.1 - 3.4e-106 351.0 0.0 3.4e-25 88.7 0.0 7.4 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 PVD28817.1 - 1.5e-52 176.2 0.2 2.4e-17 63.1 0.0 5.2 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 PVD28817.1 - 2.9e-33 114.1 0.0 2.5e-32 111.1 0.0 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 PVD28817.1 - 1.2e-25 89.8 0.0 9.1e-08 32.0 0.0 6.8 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD28817.1 - 1.6e-25 90.4 15.1 0.00077 19.9 0.4 7.9 6 2 1 7 7 7 6 AAA ATPase domain AAA_7 PF12775.7 PVD28817.1 - 1.2e-24 86.8 0.5 1.3e-05 24.8 0.0 7.7 8 0 0 8 8 8 5 P-loop containing dynein motor region AAA PF00004.29 PVD28817.1 - 5.9e-23 81.7 0.3 4.3e-05 24.0 0.0 6.8 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PVD28817.1 - 3e-17 63.4 0.7 0.031 14.8 0.0 6.5 6 0 0 6 6 6 3 ABC transporter TsaE PF02367.17 PVD28817.1 - 1.8e-16 60.3 0.9 0.073 13.1 0.0 6.3 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PVD28817.1 - 1.2e-15 58.0 10.5 0.00058 20.1 0.0 7.5 7 1 0 7 7 7 3 AAA domain Dynein_heavy PF03028.15 PVD28817.1 - 2.9e-15 56.4 0.0 0.019 15.0 0.0 6.6 6 0 0 6 6 6 2 Dynein heavy chain region D6 P-loop domain AAA_14 PF13173.6 PVD28817.1 - 5.4e-15 55.6 0.0 0.074 13.1 0.0 6.9 6 1 1 7 7 7 2 AAA domain AAA_30 PF13604.6 PVD28817.1 - 7.2e-15 55.2 0.4 0.015 15.0 0.0 6.9 7 0 0 7 7 7 2 AAA domain Sigma54_activat PF00158.26 PVD28817.1 - 1.7e-14 53.9 0.1 0.016 15.0 0.0 6.1 5 1 0 5 5 5 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PVD28817.1 - 2e-13 50.7 0.2 0.00024 21.2 0.0 5.4 5 0 0 5 5 5 2 Sigma-54 interaction domain NACHT PF05729.12 PVD28817.1 - 6.4e-13 49.0 5.5 0.033 14.1 0.0 6.7 6 0 0 6 6 6 3 NACHT domain AAA_18 PF13238.6 PVD28817.1 - 1.3e-12 48.4 3.2 0.2 12.2 0.0 6.7 6 0 0 6 6 6 2 AAA domain DUF815 PF05673.13 PVD28817.1 - 3.5e-11 42.7 2.3 0.045 12.9 0.0 6.2 6 0 0 6 6 6 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 PVD28817.1 - 6.4e-11 42.3 0.2 0.93 9.2 0.0 6.9 7 0 0 7 7 7 2 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 PVD28817.1 - 2e-10 40.1 0.1 0.048 12.6 0.0 7.5 8 1 0 8 8 8 1 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 PVD28817.1 - 2.5e-10 39.9 2.8 3.4 7.5 0.1 6.5 6 0 0 6 6 6 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 PVD28817.1 - 6.4e-10 38.8 7.3 1.7 8.0 0.0 8.0 8 1 1 9 9 8 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 PVD28817.1 - 3.8e-09 36.7 3.3 3.5 7.5 0.1 6.8 7 0 0 7 7 6 0 RsgA GTPase ATPase PF06745.13 PVD28817.1 - 9.2e-08 31.7 0.0 0.055 12.8 0.0 4.3 4 1 0 4 4 4 2 KaiC RNA_helicase PF00910.22 PVD28817.1 - 9.9e-08 32.3 0.7 0.56 10.6 0.0 6.0 6 0 0 6 6 6 1 RNA helicase AAA_33 PF13671.6 PVD28817.1 - 1.3e-07 31.9 5.4 0.75 9.9 0.0 6.4 6 1 0 6 6 6 1 AAA domain AAA_28 PF13521.6 PVD28817.1 - 1.5e-07 31.8 5.0 0.75 10.0 0.0 6.2 6 0 0 6 6 6 1 AAA domain Roc PF08477.13 PVD28817.1 - 2.7e-07 30.8 5.3 2.3 8.5 0.0 6.2 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 PVD28817.1 - 3.6e-07 30.1 0.1 7.8 6.2 0.0 4.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_8 PF12780.7 PVD28817.1 - 6.1e-07 29.0 5.3 1.6 8.0 0.1 6.6 6 2 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_25 PF13481.6 PVD28817.1 - 6.7e-07 29.1 6.2 0.33 10.5 0.0 6.2 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 PVD28817.1 - 7.6e-07 28.6 1.1 3.1 7.0 0.0 6.0 6 1 0 6 6 6 0 Zeta toxin Viral_helicase1 PF01443.18 PVD28817.1 - 2.2e-06 27.6 1.2 0.77 9.4 0.1 4.9 5 0 0 5 5 4 2 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 PVD28817.1 - 3.3e-06 26.9 5.3 0.1 12.3 0.0 5.7 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 PVD28817.1 - 5.1e-06 26.3 0.5 0.87 9.2 0.0 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain TniB PF05621.11 PVD28817.1 - 1e-05 25.1 0.0 0.45 9.9 0.0 5.4 6 0 0 6 6 6 1 Bacterial TniB protein CPT PF07931.12 PVD28817.1 - 1.3e-05 25.2 7.6 0.084 12.7 0.1 7.0 6 1 0 6 6 6 1 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 PVD28817.1 - 1.6e-05 24.9 1.0 6.6 6.8 0.0 5.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_23 PF13476.6 PVD28817.1 - 3.9e-05 24.3 0.6 1.2 9.6 0.0 5.1 6 1 0 6 6 4 1 AAA domain T2SSE PF00437.20 PVD28817.1 - 6.7e-05 22.1 3.1 2.3 7.2 0.0 5.4 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_24 PF13479.6 PVD28817.1 - 7.3e-05 22.6 1.2 18 5.0 0.1 6.0 6 1 0 6 6 6 0 AAA domain AAA_19 PF13245.6 PVD28817.1 - 8.9e-05 22.9 9.4 7.1 7.0 0.1 5.8 7 0 0 7 7 5 0 AAA domain MCM PF00493.23 PVD28817.1 - 0.00014 21.0 0.1 1.2 8.2 0.0 4.3 4 0 0 4 4 4 1 MCM P-loop domain DEAD PF00270.29 PVD28817.1 - 0.00023 21.0 0.1 13 5.5 0.0 4.5 4 0 0 4 4 4 0 DEAD/DEAH box helicase Bac_DnaA PF00308.18 PVD28817.1 - 0.00041 20.2 0.1 69 3.2 0.0 5.2 5 0 0 5 5 5 0 Bacterial dnaA protein ResIII PF04851.15 PVD28817.1 - 0.00045 20.3 0.0 2.2 8.3 0.0 4.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 PVD28817.1 - 0.0014 18.4 4.7 11 5.7 0.1 5.2 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 PVD28817.1 - 0.0025 17.8 1.0 7.3 6.5 0.0 4.0 4 0 0 4 4 3 0 Rad17 P-loop domain ATPase_2 PF01637.18 PVD28817.1 - 0.0028 17.6 0.0 30 4.4 0.0 5.2 6 0 0 6 6 5 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 PVD28817.1 - 0.0048 16.8 0.0 5.2 6.8 0.0 4.4 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 PVD28817.1 - 0.0085 15.3 2.2 12 4.9 0.0 4.6 5 1 0 5 5 5 0 TIP49 P-loop domain PhoH PF02562.16 PVD28817.1 - 0.018 14.5 0.1 10 5.5 0.0 3.3 4 0 0 4 4 2 0 PhoH-like protein AAA_15 PF13175.6 PVD28817.1 - 0.018 14.7 0.0 11 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.19 PVD28817.1 - 0.021 14.4 5.5 0.72 9.4 0.0 4.4 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 PVD28817.1 - 0.079 12.8 6.0 21 4.9 0.0 5.5 6 0 0 6 6 6 0 Deoxynucleoside kinase Ras PF00071.22 PVD28817.1 - 0.09 12.4 3.5 14 5.2 0.0 4.6 5 0 0 5 5 5 0 Ras family DnaB_C PF03796.15 PVD28817.1 - 0.18 11.1 2.7 16 4.7 0.0 4.2 5 0 0 5 5 5 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 PVD28817.1 - 0.35 10.2 1.6 22 4.3 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 PVD28817.1 - 0.84 9.5 10.1 13 5.6 0.0 5.6 7 0 0 7 7 5 0 NTPase Gtr1_RagA PF04670.12 PVD28817.1 - 2.5 7.4 5.8 3.7 6.8 0.0 3.8 6 0 0 6 6 3 0 Gtr1/RagA G protein conserved region Ist1 PF03398.14 PVD28818.1 - 2.4e-64 216.2 0.9 2.9e-64 215.9 0.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway VWA PF00092.28 PVD28819.1 - 1.8e-20 73.9 0.0 2.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD28819.1 - 3.6e-09 37.2 0.0 4.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain PsbP PF01789.16 PVD28819.1 - 0.028 14.5 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 PsbP CUB PF00431.20 PVD28821.1 - 0.0051 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 CUB domain Gal_Lectin PF02140.18 PVD28821.1 - 0.012 16.0 4.9 0.029 14.8 4.9 1.7 1 0 0 1 1 1 0 Galactose binding lectin domain RIFIN PF02009.16 PVD28822.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 PVD28822.1 - 0.18 11.9 3.9 0.078 13.1 0.9 1.9 2 0 0 2 2 2 0 Podoplanin TMEM154 PF15102.6 PVD28822.1 - 0.27 11.1 1.1 0.79 9.6 1.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family Gal_Lectin PF02140.18 PVD28822.1 - 0.39 11.2 4.2 1 9.9 4.2 1.8 1 0 0 1 1 1 0 Galactose binding lectin domain DUF4153 PF13687.6 PVD28822.1 - 1.3 8.6 4.5 1.9 8.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) DUF229 PF02995.17 PVD28823.1 - 0.0002 20.1 0.0 0.00027 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) SIMPL PF04402.14 PVD28824.1 - 1.2e-24 87.9 0.2 1.4e-24 87.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) T4_baseplate PF12322.8 PVD28824.1 - 0.019 14.4 3.1 0.044 13.3 0.5 2.0 1 1 0 2 2 2 0 T4 bacteriophage base plate protein ORC3_N PF07034.11 PVD28825.1 - 9.6e-88 294.5 3.4 9.6e-88 294.5 3.4 2.8 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 PVD28825.1 - 2.6e-18 66.5 0.0 5.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal RelB PF04221.12 PVD28825.1 - 0.063 13.2 0.0 7.3 6.6 0.0 2.6 2 0 0 2 2 2 0 RelB antitoxin DUF4375 PF14300.6 PVD28825.1 - 0.1 12.8 0.6 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Xpo1 PF08389.12 PVD28826.1 - 1.9e-26 92.9 0.6 1.5e-24 86.8 0.0 4.1 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 PVD28826.1 - 0.00012 21.9 0.4 0.00045 20.1 0.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain STAG PF08514.11 PVD28826.1 - 0.054 13.4 0.0 0.25 11.3 0.0 2.1 1 0 0 1 1 1 0 STAG domain CCDC53 PF10152.9 PVD28827.1 - 6.8e-46 156.5 0.0 8.7e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex ABC_tran_CTD PF16326.5 PVD28827.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain ALS2CR8 PF15299.6 PVD28828.1 - 6.3e-43 147.2 0.4 1.1e-42 146.4 0.4 1.3 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SYF2 PF08231.12 PVD28829.1 - 2.2e-49 167.9 20.4 2.2e-49 167.9 20.4 2.7 3 0 0 3 3 3 1 SYF2 splicing factor GTF2I PF02946.14 PVD28829.1 - 2.9e-17 62.5 0.0 7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 GTF2I-like repeat DUF3504 PF12012.8 PVD28830.1 - 1.6e-23 83.4 0.1 4.2e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Cementoin PF10511.9 PVD28830.1 - 0.18 12.2 0.3 0.62 10.4 0.3 1.9 1 0 0 1 1 1 0 Trappin protein transglutaminase binding domain DUF3504 PF12012.8 PVD28831.1 - 4.4e-14 52.7 1.1 6e-14 52.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) LAP2alpha PF11560.8 PVD28831.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha UPF0183 PF03676.14 PVD28831.1 - 0.074 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) Ank_2 PF12796.7 PVD28833.1 - 4.4e-08 33.6 0.0 0.0015 19.1 0.0 3.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD28833.1 - 4.7e-07 29.6 1.4 1 10.1 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 PVD28833.1 - 2e-05 25.0 0.4 0.46 11.1 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD28833.1 - 0.00065 20.0 1.5 18 5.8 0.0 4.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD28833.1 - 0.047 14.2 4.1 16 6.2 0.1 4.7 5 1 0 5 5 5 0 Ankyrin repeat TIP41 PF04176.13 PVD28834.1 - 5.5e-66 221.3 1.4 6.8e-66 221.0 1.4 1.1 1 0 0 1 1 1 1 TIP41-like family PTN_MK_C PF01091.18 PVD28836.1 - 1.7e-28 98.8 21.7 3.8e-12 46.4 6.6 3.2 2 1 1 3 3 3 3 PTN/MK heparin-binding protein family, C-terminal domain TSP_1 PF00090.19 PVD28836.1 - 1.9 8.8 25.5 0.11 12.8 1.1 4.3 4 0 0 4 4 4 0 Thrombospondin type 1 domain TSP_1 PF00090.19 PVD28837.1 - 0.002 18.3 4.8 0.017 15.3 0.4 2.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain PTN_MK_C PF01091.18 PVD28837.1 - 0.05 14.0 4.7 0.26 11.7 0.4 2.3 2 1 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Peptidase_C78 PF07910.13 PVD28838.1 - 1.4e-45 155.3 0.0 2.1e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Cid2 PF09774.9 PVD28838.1 - 0.12 12.8 8.3 0.28 11.6 1.5 3.0 2 1 0 2 2 2 0 Caffeine-induced death protein 2 Arm PF00514.23 PVD28839.1 - 8.4e-79 257.5 19.0 4.3e-12 45.6 0.0 9.1 8 1 0 8 8 8 8 Armadillo/beta-catenin-like repeat SYF2 PF08231.12 PVD28839.1 - 1.1e-51 175.4 19.8 1.1e-51 175.4 19.8 2.9 3 0 0 3 3 3 1 SYF2 splicing factor IBB PF01749.20 PVD28839.1 - 9.1e-24 83.7 3.0 9.1e-24 83.7 3.0 3.4 4 1 0 4 4 3 1 Importin beta binding domain Arm_3 PF16186.5 PVD28839.1 - 1.3e-22 79.1 1.0 4.3e-22 77.4 1.0 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 PVD28839.1 - 1.2e-20 73.6 5.7 3.6e-05 24.2 0.0 6.2 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 PVD28839.1 - 5.2e-18 65.2 0.0 2.2e-05 24.7 0.0 4.9 2 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 PVD28839.1 - 7.8e-17 59.9 2.3 0.03 14.6 0.0 7.7 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 PVD28839.1 - 0.00042 19.9 1.0 0.11 12.0 0.1 3.5 3 0 0 3 3 3 1 Armadillo-like V-ATPase_H_C PF11698.8 PVD28839.1 - 0.0029 17.7 0.0 0.23 11.6 0.0 3.4 3 0 0 3 3 3 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 PVD28839.1 - 0.0082 16.2 1.2 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 PVD28839.1 - 0.01 16.5 0.1 6.8 7.7 0.0 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat CTNNBL PF08216.11 PVD28839.1 - 6.4 7.0 7.9 5.5 7.2 0.0 4.5 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear zf-Sec23_Sec24 PF04810.15 PVD28840.1 - 1.6e-06 28.1 0.4 2.8e-06 27.3 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.15 PVD28840.1 - 4.5e-06 26.4 0.3 0.00023 20.8 0.3 3.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.6 PVD28840.1 - 7.4e-06 26.6 0.4 0.0053 17.4 0.4 3.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Sec23_BS PF08033.12 PVD28840.1 - 0.0041 17.8 0.0 0.013 16.2 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Cpn60_TCP1 PF00118.24 PVD28840.1 - 0.029 13.0 0.0 0.051 12.2 0.0 1.4 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family WD40 PF00400.32 PVD28843.1 - 1.5e-20 73.1 13.2 8.4e-05 23.3 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 PVD28843.1 - 0.003 16.3 6.2 4.4 5.8 2.0 4.2 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD28843.1 - 0.021 13.6 0.6 5 5.7 0.3 2.8 1 1 1 2 2 2 0 Nup133 N terminal like MBT PF02820.18 PVD28843.1 - 0.13 12.6 0.2 12 6.3 0.0 3.1 2 1 1 3 3 3 0 mbt repeat ANAPC4_WD40 PF12894.7 PVD28843.1 - 0.56 10.5 5.4 4.9 7.5 1.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NAD_binding_10 PF13460.6 PVD28844.1 - 0.02 14.8 2.0 0.077 12.9 2.0 2.0 1 0 0 1 1 1 0 NAD(P)H-binding T7SS_ESX_EspC PF10824.8 PVD28844.1 - 1.2 9.6 6.4 0.99 9.9 2.9 2.7 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Pyridox_oxase_2 PF12766.7 PVD28844.1 - 2.4 8.8 4.8 3.4 8.4 2.0 2.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 PVD28845.1 - 6.2e-07 28.7 0.3 7.4e-07 28.4 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FbpC_C_terminal PF17845.1 PVD28845.1 - 0.03 14.4 0.1 0.082 13.0 0.1 1.8 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain Forkhead PF00250.18 PVD28849.1 - 9e-12 45.1 0.0 1.9e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.5 PVD28849.1 - 1.7e-06 28.3 1.0 1.7e-06 28.3 1.0 2.5 2 0 0 2 2 2 1 Transactivation domain of FOXO protein family HDV_ag PF01517.18 PVD28849.1 - 0.029 14.2 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen SPO22 PF08631.10 PVD28850.1 - 2.2e-06 27.4 12.2 4.1e-05 23.2 2.6 3.8 3 1 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 PVD28850.1 - 0.049 13.8 3.1 8 6.9 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat GP46 PF07409.12 PVD28850.1 - 0.093 12.5 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Phage protein GP46 NiFe-hyd_HybE PF11939.8 PVD28850.1 - 0.32 10.9 2.0 1.8 8.5 0.3 2.3 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE Frizzled PF01534.17 PVD28851.1 - 8.2e-32 110.5 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 PVD28851.1 - 1e-31 109.8 2.2 1.8e-31 109.1 2.2 1.3 1 0 0 1 1 1 1 Fz domain DUF2516 PF10724.9 PVD28851.1 - 0.14 12.4 0.1 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Mid1 PF12929.7 PVD28851.1 - 2.3 7.3 5.3 7.4 5.6 0.1 2.1 1 1 1 2 2 2 0 Stretch-activated Ca2+-permeable channel component NPBW PF15180.6 PVD28852.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Neuropeptides B and W Microcephalin PF12258.8 PVD28853.1 - 0.045 13.0 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 Microcephalin protein Tim17 PF02466.19 PVD28858.1 - 1.4e-06 28.6 2.6 2.5e-06 27.8 2.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MnhB PF04039.13 PVD28858.1 - 3.9 7.8 8.4 2.8 8.3 1.2 2.6 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter PDT PF00800.18 PVD28859.1 - 0.088 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydratase NHL PF01436.21 PVD28860.1 - 1.5e-11 43.7 0.2 3.2e-09 36.4 0.1 2.5 2 0 0 2 2 2 2 NHL repeat zf-FCS PF06467.14 PVD28861.1 - 5.7e-26 90.2 73.3 4.2e-10 39.4 5.1 8.6 9 0 0 9 9 9 6 MYM-type Zinc finger with FCS sequence motif YHS PF04945.13 PVD28861.1 - 5.8e-05 23.1 28.2 0.11 12.6 0.1 7.5 8 0 0 8 8 8 4 YHS domain RRM_1 PF00076.22 PVD28862.1 - 2e-30 104.4 0.1 1.1e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 PVD28862.1 - 4.3e-25 87.7 6.3 9.1e-25 86.6 6.3 1.6 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_3 PF08777.11 PVD28862.1 - 0.0024 17.9 8.7 0.31 11.1 0.0 3.5 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 PVD28862.1 - 0.034 14.3 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 PVD28862.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mobilization_B PF17511.2 PVD28863.1 - 0.044 14.2 0.2 0.054 13.9 0.2 1.1 1 0 0 1 1 1 0 Mobilization protein B rRNA_proc-arch PF13234.6 PVD28863.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain DUF99 PF01949.16 PVD28864.1 - 0.21 11.0 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF99 Integrase_H2C2 PF17921.1 PVD28865.1 - 1.4e-07 31.5 0.2 2.8e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 PVD28866.1 - 3.7e-30 103.9 0.0 6.4e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD28866.1 - 7.2e-25 87.3 0.0 1.2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD28866.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 PVD28867.1 - 1.8e-21 75.5 37.6 3.3e-05 24.1 1.6 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD28867.1 - 1.2e-19 69.6 37.9 2.2e-05 24.6 2.0 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PVD28867.1 - 2.1e-13 49.9 26.3 0.00032 20.6 4.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.6 PVD28867.1 - 1.4e-12 47.3 48.2 0.0015 19.2 1.5 5.9 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD28867.1 - 7e-07 28.9 16.3 0.015 15.1 1.0 4.9 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-met PF12874.7 PVD28867.1 - 2.8e-06 27.5 36.5 0.078 13.4 1.2 5.8 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2HE PF16278.5 PVD28867.1 - 5.1e-05 23.6 24.5 0.003 18.0 0.3 4.9 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 PVD28867.1 - 7.1e-05 23.0 29.0 0.049 13.9 0.3 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 PVD28867.1 - 0.0043 16.9 17.0 1.6 8.6 0.3 5.1 3 1 2 5 5 5 3 C2H2 type zinc-finger (1 copy) FKBP_N_2 PF18023.1 PVD28867.1 - 0.027 14.6 4.0 13 5.9 0.0 3.7 2 1 2 4 4 4 0 BDBT FKBP like N-terminal zf-C2H2_2 PF12756.7 PVD28867.1 - 0.041 14.2 39.6 0.18 12.1 0.6 5.3 3 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) CLAMP PF14769.6 PVD28867.1 - 0.11 13.0 3.5 10 6.6 0.1 2.8 1 1 2 3 3 3 0 Flagellar C1a complex subunit C1a-32 zf-TFIIB PF13453.6 PVD28867.1 - 2.5 7.5 8.7 1.6 8.1 0.8 3.0 3 0 0 3 3 3 0 Transcription factor zinc-finger Ogr_Delta PF04606.12 PVD28867.1 - 6 6.9 26.8 4.3 7.4 0.1 5.7 3 1 3 6 6 6 0 Ogr/Delta-like zinc finger 7TM_GPCR_Srx PF10328.9 PVD28868.1 - 0.00031 20.5 0.2 0.0004 20.1 0.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD28868.1 - 0.054 13.2 0.1 0.062 12.9 0.1 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srw PF10324.9 PVD28869.1 - 7.5e-09 35.3 14.5 1.2e-08 34.7 14.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD28869.1 - 2.5e-06 27.0 11.3 3.8e-06 26.4 11.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD28869.1 - 0.00018 21.2 11.1 0.00018 21.2 11.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD28869.1 - 0.00028 20.6 7.3 0.00028 20.6 7.3 2.2 2 0 0 2 2 2 1 Srg family chemoreceptor Baculo_11_kDa PF06143.11 PVD28869.1 - 0.15 11.7 3.4 6.1 6.5 3.6 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family SHR3_chaperone PF08229.11 PVD28869.1 - 0.18 10.8 5.7 0.049 12.6 2.3 1.8 2 0 0 2 2 2 0 ER membrane protein SH3 DUF3566 PF12089.8 PVD28869.1 - 1.7 9.1 15.0 0.33 11.3 5.8 2.7 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) 7TM_GPCR_Srw PF10324.9 PVD28870.1 - 3.5e-08 33.1 10.2 6.9e-08 32.1 10.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD28870.1 - 0.00011 21.7 4.2 0.00014 21.3 4.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GWT1 PF06423.12 PVD28870.1 - 0.35 11.0 7.2 1.2 9.2 7.2 1.8 1 1 0 1 1 1 0 GWT1 7TM_GPCR_Srw PF10324.9 PVD28871.1 - 8.5e-11 41.7 12.7 1.5e-10 40.9 12.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD28871.1 - 2.7e-05 23.6 8.1 4.5e-05 22.9 8.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD28871.1 - 0.0015 18.3 7.4 0.0015 18.3 7.4 1.9 1 1 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD28871.1 - 0.0017 18.0 11.6 0.002 17.8 10.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3592 PF12158.8 PVD28871.1 - 0.28 11.2 1.3 0.46 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Renin_r PF07850.14 PVD28871.1 - 2.1 9.0 7.7 1.1 9.9 4.5 2.0 1 1 1 2 2 2 0 Renin receptor-like protein Virul_fac_BrkB PF03631.15 PVD28871.1 - 2.4 7.7 10.4 0.99 9.0 1.2 2.3 1 1 1 2 2 2 0 Virulence factor BrkB 7TM_GPCR_Srx PF10328.9 PVD28872.1 - 0.00015 21.5 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD28872.1 - 0.0012 18.6 0.2 0.0015 18.3 0.2 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7tm_1 PF00001.21 PVD28872.1 - 0.0047 16.3 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srz PF10325.9 PVD28872.1 - 0.029 13.7 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Serpentine_r_xa PF03383.15 PVD28872.1 - 0.067 13.2 0.0 0.076 13.0 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srw PF10324.9 PVD28873.1 - 1.6e-09 37.5 12.8 2.9e-09 36.7 12.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD28873.1 - 3.5e-05 23.3 7.6 8.4e-05 22.0 7.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD28873.1 - 0.00013 21.8 6.2 0.00013 21.8 6.2 2.1 2 0 0 2 2 2 1 Srg family chemoreceptor 7tm_1 PF00001.21 PVD28875.1 - 1.1e-06 28.3 18.1 5.5e-05 22.6 9.2 2.5 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD28875.1 - 4.2e-06 26.6 29.8 0.0012 18.6 6.4 2.9 2 1 1 3 3 3 2 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD28875.1 - 3.8e-05 23.4 29.7 0.02 14.5 7.6 2.8 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx IlvB_leader PF08049.11 PVD28875.1 - 0.064 13.2 6.9 4 7.4 0.1 3.6 3 0 0 3 3 3 0 IlvB leader peptide SHR3_chaperone PF08229.11 PVD28875.1 - 0.095 11.7 8.6 0.067 12.2 0.9 3.1 3 0 0 3 3 3 0 ER membrane protein SH3 Ferric_reduct PF01794.19 PVD28875.1 - 0.6 10.2 19.0 0.21 11.7 2.8 3.9 2 2 2 4 4 4 0 Ferric reductase like transmembrane component DUF3566 PF12089.8 PVD28875.1 - 1.3 9.4 22.9 2.3 8.6 5.4 4.1 4 0 0 4 4 4 0 Transmembrane domain of unknown function (DUF3566) DUF4834 PF16118.5 PVD28875.1 - 2.1 9.4 7.5 4.9 8.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Renin_r PF07850.14 PVD28875.1 - 3.1 8.5 12.5 4.6 7.9 1.7 3.0 3 0 0 3 3 3 0 Renin receptor-like protein Baculo_11_kDa PF06143.11 PVD28875.1 - 9 6.0 13.0 3.6 7.2 2.7 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1736 PF08409.11 PVD28876.1 - 7e-27 93.2 0.9 3.3e-26 91.1 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) RCR PF12273.8 PVD28876.1 - 0.17 12.6 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TPR_2 PF07719.17 PVD28877.1 - 5.1e-33 110.5 13.5 6.3e-06 25.9 0.2 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD28877.1 - 7.9e-28 95.1 9.7 1.3e-06 28.0 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD28877.1 - 2.6e-25 86.5 2.3 0.00018 21.5 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 PVD28877.1 - 7.2e-21 72.6 13.7 0.0038 17.1 0.3 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 PVD28877.1 - 8.5e-21 73.4 4.4 0.00013 21.6 0.0 6.9 5 2 2 7 7 7 4 TPR repeat TPR_16 PF13432.6 PVD28877.1 - 6.9e-20 71.4 24.5 3.1e-07 30.9 0.7 5.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 PVD28877.1 - 1.5e-19 70.0 27.5 0.0015 18.8 3.4 6.5 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 PVD28877.1 - 7.4e-19 66.7 14.0 0.00084 19.6 0.1 8.3 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD28877.1 - 1.6e-16 59.6 20.5 0.0022 18.7 1.0 7.3 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 PVD28877.1 - 6.4e-13 48.1 33.0 0.027 14.4 0.8 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 PVD28877.1 - 3.4e-11 43.5 10.6 0.0071 16.8 0.0 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD28877.1 - 2.3e-09 37.1 13.3 2e-07 30.7 8.5 2.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 PVD28877.1 - 3.3e-07 30.3 27.4 0.035 14.7 4.2 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat NARP1 PF12569.8 PVD28877.1 - 1.4e-06 27.5 4.7 6.7e-06 25.3 0.4 2.7 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 PVD28877.1 - 5.5e-05 23.0 11.2 0.1 12.3 0.2 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 PVD28877.1 - 0.0002 20.7 10.4 0.00036 19.8 5.4 3.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD28877.1 - 0.0014 18.7 14.3 3.7 7.8 4.8 4.7 2 2 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD28877.1 - 0.0016 19.0 10.2 0.53 11.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 PVD28877.1 - 0.0019 18.5 6.8 0.15 12.4 0.0 4.0 1 1 3 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 PVD28877.1 - 0.0021 17.5 2.3 1.5 8.2 0.0 3.0 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 PVD28877.1 - 0.0023 18.1 6.1 0.027 14.7 0.1 4.1 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 PVD28877.1 - 0.0024 17.5 1.5 0.039 13.6 0.1 2.9 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 PVD28877.1 - 0.0028 17.1 3.5 0.019 14.4 0.2 2.9 2 1 2 4 4 4 1 Coatomer epsilon subunit MIT PF04212.18 PVD28877.1 - 0.0035 17.4 1.7 2.6 8.2 0.0 3.9 4 1 1 5 5 3 1 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 PVD28877.1 - 0.0088 15.8 3.0 0.062 13.0 0.3 3.0 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) 2_5_RNA_ligase2 PF13563.6 PVD28877.1 - 0.018 14.9 0.2 0.038 13.9 0.2 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily TPPII_N PF12583.8 PVD28877.1 - 0.046 14.3 5.6 0.068 13.7 0.2 3.5 4 1 1 5 5 4 0 Tripeptidyl peptidase II N terminal TPR_5 PF12688.7 PVD28877.1 - 0.15 12.3 3.9 0.48 10.7 1.2 2.8 1 1 2 3 3 3 0 Tetratrico peptide repeat HemY_N PF07219.13 PVD28877.1 - 0.24 11.6 8.8 1.2 9.4 0.0 3.8 3 1 0 3 3 3 0 HemY protein N-terminus LRR_6 PF13516.6 PVD28878.1 - 3.9e-09 35.8 19.8 0.24 11.5 0.1 6.8 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 PVD28878.1 - 0.5 10.9 14.4 1.7 9.2 1.7 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD28878.1 - 0.91 9.3 11.7 0.21 11.4 2.4 3.8 2 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 PVD28878.1 - 0.95 10.3 12.2 21 6.2 0.1 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat PUFD PF16553.5 PVD28879.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Lig_chan PF00060.26 PVD28882.1 - 5e-57 191.9 0.1 7.7e-57 191.3 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 PVD28882.1 - 7.4e-40 137.1 0.1 2.2e-25 89.5 0.0 2.5 1 1 1 2 2 2 2 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 PVD28882.1 - 5.6e-33 113.6 0.0 1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD28882.1 - 2e-19 69.9 0.0 3.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 PVD28882.1 - 0.012 15.3 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Lig_chan PF00060.26 PVD28883.1 - 0.0054 16.6 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 Ligand-gated ion channel EphA2_TM PF14575.6 PVD28883.1 - 0.094 13.6 0.4 0.18 12.7 0.4 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 PVD28883.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Lig_chan-Glu_bd PF10613.9 PVD28884.1 - 4.7e-41 139.6 0.1 1.4e-40 138.1 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD28884.1 - 1.8e-34 119.4 0.5 5.4e-18 65.2 0.1 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Lig_chan PF00060.26 PVD28884.1 - 1.7e-28 99.3 0.0 3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD28884.1 - 2.5e-11 43.5 0.0 4.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 RNR_Alpha PF17975.1 PVD28884.1 - 0.022 15.3 0.3 0.17 12.4 0.1 2.6 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain CopK PF11525.8 PVD28884.1 - 0.24 11.1 0.9 0.52 10.0 0.9 1.5 1 0 0 1 1 1 0 Copper resistance protein K Pkinase_Tyr PF07714.17 PVD28885.1 - 1.2e-60 205.0 0.0 2.1e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD28885.1 - 1.6e-54 185.1 0.0 4.5e-54 183.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 PVD28885.1 - 0.0015 18.5 0.0 0.064 13.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family CENP-H PF05837.12 PVD28885.1 - 0.23 11.9 7.7 0.13 12.6 4.5 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 PVD28885.1 - 1.2 8.9 4.8 3.3 7.5 2.3 2.3 1 1 1 2 2 2 0 Septum formation initiator GCFC PF07842.12 PVD28886.1 - 1.2e-30 107.1 0.1 4.9e-30 105.1 0.1 2.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein UPF0242 PF06785.11 PVD28886.1 - 0.012 15.7 1.4 0.012 15.7 1.4 4.4 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus OKR_DC_1_C PF03711.15 PVD28886.1 - 1.9 8.8 3.6 7.4 6.9 2.3 2.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain SAND PF01342.21 PVD28887.1 - 1.5e-28 98.3 0.1 4e-28 96.9 0.1 1.8 1 0 0 1 1 1 1 SAND domain ATP_bind_2 PF03668.15 PVD28887.1 - 0.13 11.5 1.8 0.2 10.9 1.8 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family PAT1 PF09770.9 PVD28888.1 - 1.1e-09 37.3 15.7 1.5e-07 30.2 0.0 4.2 4 1 0 4 4 4 3 Topoisomerase II-associated protein PAT1 EF-hand_9 PF14658.6 PVD28889.1 - 3.1e-17 62.6 0.1 7e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain KASH_CCD PF14662.6 PVD28889.1 - 1.9e-06 27.9 42.2 1.9e-06 27.9 42.2 3.5 2 2 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 PVD28889.1 - 0.0012 18.5 18.8 0.0012 18.5 18.8 3.3 2 1 1 3 3 3 2 Leucine zipper GvpL_GvpF PF06386.11 PVD28889.1 - 0.37 10.7 11.6 1.3 8.8 11.6 1.9 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TetR_C_2 PF08361.11 PVD28889.1 - 1.9 8.6 5.8 0.59 10.3 0.7 2.8 3 0 0 3 3 3 0 MAATS-type transcriptional repressor, C-terminal region DUF1877 PF08974.10 PVD28889.1 - 2 8.5 8.3 4.8 7.2 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) DUF812 PF05667.11 PVD28889.1 - 5.5 5.8 43.3 9.9 4.9 3.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 PVD28889.1 - 10 6.2 25.6 1.2 9.1 6.5 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) MRVI1 PF05781.12 PVD28891.1 - 1.2e-42 146.4 6.9 1.2e-42 146.4 6.9 2.9 1 1 1 2 2 2 1 MRVI1 protein Baculo_PEP_C PF04513.12 PVD28891.1 - 0.0081 16.2 0.8 2.5 8.1 0.1 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SPOUT_MTase PF02590.17 PVD28891.1 - 0.43 10.6 3.5 0.26 11.2 0.2 2.2 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase FlaC_arch PF05377.11 PVD28891.1 - 1.4 9.3 4.9 4.1 7.9 0.3 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ras PF00071.22 PVD28892.1 - 7.1e-21 74.5 0.0 9.2e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD28892.1 - 0.0072 16.5 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD28892.1 - 0.061 12.8 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD28892.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Dopey_N PF04118.14 PVD28894.1 - 9.7e-88 294.2 5.2 2e-63 214.3 0.1 2.7 1 1 1 2 2 2 2 Dopey, N-terminal Nitrate_red_del PF02613.15 PVD28894.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Nitrate reductase delta subunit MOLO1 PF17175.4 PVD28895.1 - 3.4e-24 85.2 0.1 4.6e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 PVD28895.1 - 1.9e-06 28.1 0.0 5.4e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 TPM domain DUF4028 PF13220.6 PVD28896.1 - 0.14 12.0 0.8 22 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) ANAPC4_WD40 PF12894.7 PVD28897.1 - 0.074 13.4 0.0 0.29 11.5 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM247 PF15444.6 PVD28897.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 DUF4482 PF14818.6 PVD28897.1 - 0.14 13.1 2.8 0.3 12.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) Complex1_LYR PF05347.15 PVD28897.1 - 0.45 10.6 4.2 5.9 7.0 4.2 2.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) HA2 PF04408.23 PVD28898.1 - 1.9e-21 76.4 0.1 4.6e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD28898.1 - 5.9e-21 74.6 0.1 1.8e-20 73.1 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD28898.1 - 5e-16 59.0 0.0 1.4e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PVD28898.1 - 1.2e-05 25.6 0.0 4.1e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 PVD28898.1 - 0.0002 21.2 0.3 0.00052 19.8 0.3 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PVD28898.1 - 0.0083 16.5 0.2 0.023 15.1 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD28898.1 - 0.013 15.2 0.5 0.029 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD28898.1 - 0.024 15.2 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 PVD28898.1 - 0.034 14.1 0.8 1.9 8.5 0.6 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit LIM PF00412.22 PVD28899.1 - 9.3e-59 195.5 96.6 1.9e-12 47.2 4.9 7.2 7 0 0 7 7 7 6 LIM domain PET PF06297.14 PVD28899.1 - 1.3e-25 89.5 0.0 2.9e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 PET Domain Cpn60_TCP1 PF00118.24 PVD28903.1 - 3.5e-149 497.6 11.8 4e-149 497.4 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Monellin PF09200.10 PVD28903.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Monellin TUDOR PF00567.24 PVD28904.1 - 2.1e-107 353.9 6.8 1.1e-25 90.1 0.0 6.7 5 1 1 6 6 6 6 Tudor domain SMN PF06003.12 PVD28904.1 - 6.1e-10 38.8 0.0 0.011 15.0 0.0 4.4 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) DUF4537 PF15057.6 PVD28904.1 - 5.8e-09 36.0 1.8 0.22 11.5 0.0 5.1 4 1 0 4 4 4 3 Domain of unknown function (DUF4537) zf-B_box PF00643.24 PVD28904.1 - 9.1e-08 32.1 5.4 2.4e-07 30.8 5.4 1.8 1 0 0 1 1 1 1 B-box zinc finger Spectrin PF00435.21 PVD28904.1 - 1.2e-06 28.9 2.6 1.5e-05 25.4 2.5 2.9 3 0 0 3 3 3 1 Spectrin repeat Agenet PF05641.12 PVD28904.1 - 8.7e-06 26.1 1.2 0.14 12.6 0.0 4.7 4 0 0 4 4 4 1 Agenet domain zf-UBR PF02207.20 PVD28904.1 - 0.0088 16.2 3.3 0.028 14.6 3.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF5063 PF16702.5 PVD28904.1 - 0.29 11.5 3.1 13 6.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5063) Phosphodiest PF01663.22 PVD28905.1 - 7.3e-64 216.6 0.1 8.6e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD28905.1 - 0.0001 21.8 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 PVD28905.1 - 0.013 14.9 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.17 PVD28905.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 PVD28906.1 - 1e-69 235.9 0.9 1.3e-69 235.5 0.9 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD28906.1 - 4e-06 26.5 0.0 3.8e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 PVD28906.1 - 0.00017 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 PVD28906.1 - 0.033 12.8 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PglZ PF08665.12 PVD28906.1 - 0.035 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 PglZ domain ADK PF00406.22 PVD28907.1 - 1.2e-53 181.2 12.9 6.1e-23 81.6 0.1 6.5 6 0 0 6 6 6 4 Adenylate kinase AAA_17 PF13207.6 PVD28907.1 - 1.5e-24 86.9 52.5 1.7e-09 38.3 0.0 9.6 8 2 2 10 10 7 5 AAA domain FAP206 PF12018.8 PVD28907.1 - 9.6e-19 67.9 21.3 5e-07 29.5 0.0 7.4 8 0 0 8 8 7 3 Domain of unknown function AAA_33 PF13671.6 PVD28907.1 - 2.5e-16 60.1 1.8 0.0005 20.3 0.0 5.4 5 0 0 5 5 4 4 AAA domain AAA_18 PF13238.6 PVD28907.1 - 1.1e-14 55.1 20.0 4.1e-06 27.4 0.0 7.3 6 2 0 6 6 6 4 AAA domain AAA_22 PF13401.6 PVD28907.1 - 1.4e-12 48.1 0.4 0.084 13.2 0.0 5.1 4 0 0 4 4 4 3 AAA domain YHS PF04945.13 PVD28907.1 - 4.4e-12 45.9 1.4 0.03 14.4 0.1 4.8 4 0 0 4 4 4 3 YHS domain AAA PF00004.29 PVD28907.1 - 4.3e-09 36.9 15.4 0.0021 18.5 0.0 5.5 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD28907.1 - 1e-08 35.7 18.6 0.0057 17.0 0.2 6.8 7 0 0 7 7 7 2 AAA ATPase domain AAA_14 PF13173.6 PVD28907.1 - 2.8e-08 33.8 0.3 5.3 7.1 0.0 4.9 4 0 0 4 4 4 1 AAA domain Hydin_ADK PF17213.3 PVD28907.1 - 8.7e-08 32.7 8.1 8.7e-08 32.7 8.1 7.0 7 2 0 7 7 4 1 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 PVD28907.1 - 3.3e-07 30.2 2.6 0.31 10.7 0.0 4.9 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.22 PVD28907.1 - 5.1e-07 30.1 1.0 2.7 8.4 0.0 5.6 5 0 0 5 5 5 1 RNA helicase NACHT PF05729.12 PVD28907.1 - 8.8e-07 29.0 1.9 0.00091 19.2 0.0 4.4 4 0 0 4 4 4 1 NACHT domain MMR_HSR1 PF01926.23 PVD28907.1 - 1.8e-06 28.0 1.0 0.41 10.8 0.0 4.2 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA_28 PF13521.6 PVD28907.1 - 3.1e-06 27.5 0.8 0.0016 18.7 0.0 7.2 7 1 0 7 7 5 4 AAA domain Roc PF08477.13 PVD28907.1 - 6.9e-06 26.3 0.7 1.5 9.1 0.0 4.6 4 1 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 PVD28907.1 - 2.8e-05 24.2 1.5 0.25 11.3 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 PVD28907.1 - 8.8e-05 22.3 9.8 0.033 13.9 0.1 5.6 6 0 0 6 6 4 1 Cytidylate kinase ABC_tran PF00005.27 PVD28907.1 - 9e-05 23.0 15.0 0.21 12.1 0.3 5.7 6 0 0 6 6 4 2 ABC transporter KTI12 PF08433.10 PVD28907.1 - 0.00022 20.8 3.5 0.22 11.0 1.3 4.3 4 0 0 4 4 3 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 PVD28907.1 - 0.0003 20.6 0.0 0.12 12.1 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RuvB_N PF05496.12 PVD28907.1 - 0.00049 19.9 0.5 1.4 8.6 0.0 3.6 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 PVD28907.1 - 0.00052 20.0 0.8 6.8 6.6 0.0 3.9 4 0 0 4 4 3 0 NTPase Mg_chelatase PF01078.21 PVD28907.1 - 0.0063 15.9 0.3 4.5 6.6 0.0 4.0 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 PVD28907.1 - 0.0065 16.4 0.3 42 4.0 0.0 4.2 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 PVD28907.1 - 0.02 14.8 0.1 0.82 9.6 0.0 3.5 3 1 0 3 3 3 0 RsgA GTPase TsaE PF02367.17 PVD28907.1 - 0.036 14.1 0.0 8.7 6.4 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_26 PF13500.6 PVD28907.1 - 0.056 13.3 1.9 0.35 10.7 1.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PVD28907.1 - 0.087 13.2 0.3 11 6.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.9 PVD28907.1 - 0.094 12.5 0.1 39 4.0 0.0 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 PVD28907.1 - 0.18 11.2 0.5 5.4 6.4 0.0 3.3 4 0 0 4 4 3 0 Poxvirus A32 protein Taxilin PF09728.9 PVD28908.1 - 1.4e-98 329.9 61.7 2e-98 329.4 61.7 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Virulence_fact PF13769.6 PVD28908.1 - 1.1 9.5 7.1 1.7 8.9 2.8 3.1 2 0 0 2 2 2 0 Virulence factor Headcase PF16002.5 PVD28909.1 - 5.9e-69 231.5 10.0 2.8e-63 213.0 10.7 2.3 2 0 0 2 2 2 2 Headcase protein HECA PF15353.6 PVD28909.1 - 1.9e-45 153.3 5.6 1.9e-45 153.3 5.6 1.8 2 0 0 2 2 2 1 Headcase protein family homologue BSD PF03909.17 PVD28911.1 - 3.3e-16 59.0 0.7 3.3e-16 59.0 0.7 2.1 2 0 0 2 2 2 1 BSD domain Mt_ATP-synt_B PF05405.14 PVD28911.1 - 0.0094 15.6 0.2 0.0094 15.6 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Methyltransf_32 PF13679.6 PVD28911.1 - 0.21 11.6 1.3 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain PAC1 PF16094.5 PVD28912.1 - 1.2e-68 231.3 1.0 2e-68 230.6 1.0 1.3 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Endostatin PF06482.11 PVD28912.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_M48_N PF16491.5 PVD28913.1 - 2.7e-66 222.9 10.4 2.7e-66 222.9 10.4 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 PVD28913.1 - 4.5e-57 193.0 0.0 9.4e-57 192.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 CDC45 PF02724.14 PVD28913.1 - 0.00018 20.0 6.5 0.00025 19.5 6.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.22 PVD28913.1 - 0.0024 17.2 0.2 0.0049 16.1 0.2 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter SpoIIIAH PF12685.7 PVD28913.1 - 0.11 12.3 3.0 0.17 11.7 3.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 PVD28913.1 - 0.31 11.4 3.4 0.48 10.8 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 PVD28913.1 - 0.38 10.5 6.9 0.68 9.7 6.9 1.4 1 0 0 1 1 1 0 Coilin N-terminus Connexin PF00029.19 PVD28913.1 - 0.49 10.1 3.2 0.21 11.3 0.2 1.9 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 PVD28913.1 - 1.6 8.5 9.8 2.5 7.8 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 PVD28913.1 - 5.3 5.7 5.9 7.4 5.2 5.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 tRNA_U5-meth_tr PF05958.11 PVD28914.1 - 1.4e-10 40.7 0.1 4.2e-10 39.1 0.1 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PVD28914.1 - 5.3e-07 29.5 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD28914.1 - 7.3e-05 22.4 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PVD28914.1 - 0.00014 21.4 1.9 0.00023 20.6 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PVD28914.1 - 0.0011 19.6 0.1 0.0025 18.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PVD28914.1 - 0.0023 17.9 0.1 0.0053 16.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD28914.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 PVD28914.1 - 0.023 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 PVD28914.1 - 0.061 12.9 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 PVD28914.1 - 0.062 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 PVD28914.1 - 0.08 12.3 0.3 0.16 11.2 0.3 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Bcl-2 PF00452.19 PVD28915.1 - 3.9e-25 88.4 1.1 1.2e-24 86.8 0.1 2.0 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Exo_endo_phos PF03372.23 PVD28916.1 - 3.8e-08 33.1 0.2 0.00035 20.2 0.0 2.4 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD28916.1 - 2.3e-05 24.2 0.9 0.24 11.3 0.1 3.3 2 2 0 2 2 2 2 Endonuclease-reverse transcriptase CarS-like PF01864.17 PVD28916.1 - 0.00019 21.5 0.9 0.071 13.1 0.2 2.3 2 0 0 2 2 2 2 CDP-archaeol synthase NADH_B2 PF14813.6 PVD28917.1 - 3.7e-27 93.9 3.6 7.2e-27 93.0 3.6 1.5 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF4537 PF15057.6 PVD28918.1 - 3.5e-26 91.6 0.0 7.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) VWA_3 PF13768.6 PVD28918.1 - 6.5e-11 42.4 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD28918.1 - 1.1e-06 29.2 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD28918.1 - 1.5e-05 25.4 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PVD28918.1 - 0.048 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein UPF0489 PF12640.7 PVD28919.1 - 0.023 14.9 2.7 0.045 14.0 2.7 1.6 1 0 0 1 1 1 0 UPF0489 domain DUF1298 PF06974.13 PVD28920.1 - 1e-10 41.7 0.0 2.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 PVD28920.1 - 4.4e-06 26.7 0.5 2.7e-05 24.1 0.5 2.3 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain GLTSCR1 PF15249.6 PVD28920.1 - 0.15 12.5 1.2 0.38 11.2 1.2 1.7 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein polyprenyl_synt PF00348.17 PVD28922.1 - 1.3e-19 70.2 0.0 1.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MCD PF05292.11 PVD28923.1 - 8.3e-99 330.3 0.0 1.1e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 PVD28923.1 - 1.9e-17 63.2 0.1 5.2e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain MCD PF05292.11 PVD28925.1 - 6.1e-08 32.5 0.0 6.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Retrotrans_gag PF03732.17 PVD28926.1 - 0.00042 20.5 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Glyco_transf_92 PF01697.27 PVD28927.1 - 5.2e-32 111.5 0.0 9.4e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28927.1 - 0.0036 17.8 0.5 0.0086 16.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Hepatitis_core PF00906.20 PVD28927.1 - 0.083 12.4 0.1 0.083 12.4 0.1 1.7 2 0 0 2 2 2 0 Hepatitis core antigen DUF4799 PF16056.5 PVD28927.1 - 0.31 10.1 5.2 0.094 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4799) Pyr_redox_2 PF07992.14 PVD28928.1 - 9.3e-31 107.1 0.2 3.6e-16 59.3 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD28928.1 - 3e-08 33.3 0.6 0.0022 17.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 PVD28928.1 - 2e-07 30.8 0.0 4.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain FAD_binding_2 PF00890.24 PVD28928.1 - 0.00033 19.8 0.7 0.14 11.2 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 PVD28928.1 - 0.0017 18.9 0.2 0.22 12.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD28928.1 - 0.0038 17.4 0.2 0.011 15.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 PVD28928.1 - 0.0047 16.1 0.1 1.2 8.2 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 PVD28928.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PVD28928.1 - 0.014 14.6 0.1 0.032 13.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 PVD28928.1 - 0.018 14.1 0.6 0.055 12.5 0.2 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 PVD28928.1 - 0.029 14.8 0.2 1.5 9.3 0.1 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 PVD28928.1 - 0.078 11.7 0.3 0.27 9.9 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 PVD28928.1 - 0.079 13.0 0.1 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 PVD28928.1 - 0.1 11.7 1.8 2.2 7.3 0.9 2.4 1 1 1 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PVD28928.1 - 0.36 10.1 2.6 0.48 9.7 1.2 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Insulin PF00049.18 PVD28929.1 - 3.6e-11 43.9 0.7 4.7e-11 43.5 0.7 1.2 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 PVD28929.1 - 0.00049 20.0 2.9 0.23 11.5 0.4 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Glyco_transf_92 PF01697.27 PVD28933.1 - 1.6e-44 152.6 0.0 2.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28933.1 - 6.6e-05 23.4 0.1 0.00014 22.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Acetyltransf_7 PF13508.7 PVD28933.1 - 0.12 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_92 PF01697.27 PVD28934.1 - 6.1e-46 157.2 0.0 9.3e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD28934.1 - 0.00083 19.8 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Fam20C PF06702.12 PVD28935.1 - 3e-07 30.5 0.6 6.7e-06 26.1 0.6 2.1 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 Orthopox_A43R PF06517.11 PVD28935.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A43R protein DUF1661 PF07877.11 PVD28938.1 - 0.066 12.9 4.2 0.12 12.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DNA_pol_A PF00476.20 PVD28941.1 - 2.3e-104 349.5 0.2 4.2e-104 348.6 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 PVD28941.1 - 1.2e-16 61.0 0.0 2.1e-15 57.0 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD28941.1 - 3.1e-11 43.6 3.6 6.6e-10 39.3 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DNA_pol_P_Exo PF18049.1 PVD28941.1 - 0.029 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo DUF4332 PF14229.6 PVD28941.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) CS PF04969.16 PVD28942.1 - 8.5e-17 61.9 0.2 2.8e-16 60.3 0.0 2.0 2 0 0 2 2 1 1 CS domain Nudc_N PF14050.6 PVD28942.1 - 8.5e-13 48.1 0.6 2e-12 46.9 0.1 1.9 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. NuDC PF16273.5 PVD28942.1 - 3.1e-10 40.4 31.1 3.1e-10 40.4 31.1 3.0 2 2 1 3 3 2 1 Nuclear distribution C domain Allexi_40kDa PF05549.11 PVD28942.1 - 0.23 11.0 4.7 0.16 11.5 0.8 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Hid1 PF12722.7 PVD28942.1 - 0.38 8.8 14.5 0.6 8.2 14.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 PVD28942.1 - 0.65 8.7 11.6 1 8.0 11.6 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_L22 PF00237.19 PVD28942.1 - 1.8 8.8 6.8 3.4 7.9 6.8 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Atg14 PF10186.9 PVD28942.1 - 1.9 7.5 9.6 3.3 6.7 9.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Borrelia_P83 PF05262.11 PVD28942.1 - 2.3 6.6 27.0 0.032 12.7 20.2 1.4 2 0 0 2 2 2 0 Borrelia P83/100 protein XRN_M PF17846.1 PVD28942.1 - 2.5 7.0 18.4 0.1 11.5 12.5 1.6 2 0 0 2 2 2 0 Xrn1 helical domain V_ATPase_I PF01496.19 PVD28942.1 - 3.9 5.3 10.9 6 4.6 10.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 PVD28942.1 - 6.7 5.6 16.1 0.21 10.6 9.8 1.6 2 0 0 2 2 2 0 Solute carrier family 12 Nup192 PF11894.8 PVD28943.1 - 0 1157.3 3.5 0 1156.9 3.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Tub PF01167.18 PVD28945.1 - 4.8e-33 114.9 0.0 1.8e-27 96.6 0.1 2.6 2 1 0 2 2 2 2 Tub family ANAPC4_WD40 PF12894.7 PVD28945.1 - 1.6e-09 38.0 0.8 0.0012 19.1 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PVD28945.1 - 0.012 13.6 0.0 0.024 12.7 0.0 1.5 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.12 PVD28945.1 - 0.049 13.6 0.5 7.8 6.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mucin PF01456.17 PVD28945.1 - 0.05 13.6 32.3 0.1 12.6 32.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 PVD28945.1 - 0.12 10.5 14.9 0.17 9.9 14.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sec-ASP3 PF15432.6 PVD28945.1 - 0.15 12.2 0.3 0.59 10.3 0.1 2.0 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 WD40 PF00400.32 PVD28945.1 - 0.18 12.7 4.1 2 9.4 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat SOCS_box PF07525.16 PVD28945.1 - 0.22 11.9 3.0 0.45 10.9 3.0 1.6 1 0 0 1 1 1 0 SOCS box DUF3527 PF12043.8 PVD28945.1 - 0.54 9.8 2.3 0.57 9.7 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3527) WD40 PF00400.32 PVD28946.1 - 9.8e-27 92.7 10.7 6.2e-08 33.2 1.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28946.1 - 6.6e-15 55.2 0.0 0.0032 17.7 0.0 5.2 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 PVD28946.1 - 9.1e-07 28.7 0.3 7.4 6.6 0.1 4.6 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 PVD28946.1 - 0.0001 22.3 0.8 0.11 12.4 0.0 3.5 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 PVD28946.1 - 0.00046 19.3 0.0 1.6 7.7 0.0 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 PVD28946.1 - 0.0011 18.6 2.0 6.5 6.5 0.0 4.7 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature eIF2A PF08662.11 PVD28946.1 - 0.0027 17.6 0.0 0.93 9.3 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 PVD28946.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region DUF4994 PF16385.5 PVD28948.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function Sulfatase PF00884.23 PVD28948.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 PVD28948.1 - 0.034 14.9 0.0 0.046 14.4 0.0 1.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD28948.1 - 0.22 11.8 0.0 0.51 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) 7tm_1 PF00001.21 PVD28949.1 - 3.6e-28 98.6 7.5 5.4e-28 98.0 7.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 PVD28949.1 - 0.00014 21.5 1.6 0.00031 20.4 1.6 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD28949.1 - 0.00062 20.1 1.4 0.002 18.5 1.4 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) 7tm_4 PF13853.6 PVD28949.1 - 0.83 9.3 8.3 2.1 8.0 8.3 1.7 1 1 0 1 1 1 0 Olfactory receptor LRR_8 PF13855.6 PVD28950.1 - 8e-50 166.5 42.6 3.4e-13 49.1 4.7 5.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD28950.1 - 2.2e-21 75.5 14.0 3.5e-05 24.1 0.3 6.6 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 PVD28950.1 - 2.6e-21 76.2 5.5 3.9e-21 75.5 5.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 PVD28950.1 - 3.2e-16 59.4 0.1 6.6e-07 29.3 0.6 2.8 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD28950.1 - 1.4e-08 34.1 12.0 0.37 11.5 0.1 8.7 7 2 1 9 9 9 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD28950.1 - 1.5e-08 34.3 8.3 0.0068 15.9 1.1 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 PVD28950.1 - 4.8e-05 23.1 20.3 4.4 7.6 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat 7TM_GPCR_Srsx PF10320.9 PVD28950.1 - 0.0023 17.4 7.4 0.0041 16.5 7.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRRNT PF01462.18 PVD28950.1 - 0.018 14.7 3.0 0.047 13.4 3.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Folliculin PF11704.8 PVD28951.1 - 4.5e-08 33.2 0.2 1.2e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport HAUS-augmin3 PF14932.6 PVD28952.1 - 0.27 10.8 3.2 0.25 10.9 1.1 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 RNB PF00773.19 PVD28953.1 - 2.2e-20 73.3 2.0 4.7e-20 72.2 2.0 1.6 1 1 0 1 1 1 1 RNB domain AbiH PF14253.6 PVD28953.1 - 0.3 10.9 1.4 0.42 10.4 0.8 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH AAA_12 PF13087.6 PVD28954.1 - 1.3e-46 158.8 0.0 2.2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD28954.1 - 1.9e-15 57.4 0.6 3.1e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain PKD PF00801.20 PVD28954.1 - 2.5e-13 49.7 23.5 6.7e-06 25.9 0.8 6.2 6 0 0 6 6 6 3 PKD domain UvrD_C PF13361.6 PVD28954.1 - 1.4e-06 27.9 0.0 1.6e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 PVD28954.1 - 3.5e-05 23.5 0.0 0.00013 21.7 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PVD28954.1 - 0.0006 19.6 0.2 0.42 10.3 0.0 2.9 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 PVD28954.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ASH PF15780.5 PVD28954.1 - 0.0047 17.1 3.5 5.8 7.2 0.1 4.4 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AAA_19 PF13245.6 PVD28954.1 - 0.031 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3723 PF12520.8 PVD28954.1 - 0.083 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) REJ PF02010.15 PVD28955.1 - 2.7e-44 151.7 1.0 3.9e-44 151.2 0.3 1.6 2 0 0 2 2 2 1 REJ domain PLAT PF01477.23 PVD28955.1 - 6.6e-16 58.9 0.0 1.7e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain PKD_channel PF08016.12 PVD28956.1 - 4.5e-11 42.1 0.7 9.5e-11 41.0 0.1 1.9 2 0 0 2 2 2 1 Polycystin cation channel PKD_channel PF08016.12 PVD28957.1 - 1.5e-25 89.8 15.9 4.9e-24 84.8 10.9 2.0 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 PVD28957.1 - 2.7e-08 33.4 21.1 6.9e-08 32.0 21.1 1.5 1 1 0 1 1 1 1 Ion transport protein Cytochrome-c551 PF10643.9 PVD28957.1 - 2.8 7.5 7.8 4.1 6.9 7.8 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 PKD PF00801.20 PVD28958.1 - 9.4e-18 63.8 43.1 0.00015 21.6 5.7 9.8 7 2 1 9 9 9 6 PKD domain DUF824 PF05688.11 PVD28958.1 - 1.2e-05 25.0 1.0 3.2 7.6 0.0 3.9 4 0 0 4 4 4 3 Salmonella repeat of unknown function (DUF824) Rdx PF10262.9 PVD28958.1 - 0.0004 20.5 0.5 38 4.6 0.0 5.0 4 1 0 4 4 4 0 Rdx family Peripla_BP_7 PF18610.1 PVD28958.1 - 0.028 14.5 0.9 48 4.2 0.0 4.1 4 0 0 4 4 4 0 Periplasmic binding protein domain DUF3553 PF12073.8 PVD28958.1 - 0.24 11.1 1.6 43 3.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3553) PKD_3 PF16820.5 PVD28958.1 - 0.41 10.4 14.6 7.7 6.4 0.1 6.7 7 0 0 7 7 7 0 PKD-like domain Cthe_2159 PF14262.6 PVD28958.1 - 2.8 7.2 4.9 42 3.3 0.1 3.1 3 0 0 3 3 3 0 Carbohydrate-binding domain-containing protein Cthe_2159 Germane PF10646.9 PVD28958.1 - 9.2 7.1 6.8 18 6.2 0.2 3.7 3 0 0 3 3 3 0 Sporulation and spore germination PLAT PF01477.23 PVD28960.1 - 7.1e-07 29.8 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain PKD_channel PF08016.12 PVD28961.1 - 1.4e-79 267.8 14.7 1.4e-79 267.8 14.7 1.8 3 0 0 3 3 3 1 Polycystin cation channel Ion_trans PF00520.31 PVD28961.1 - 1.4e-13 50.6 25.7 1.4e-13 50.6 25.7 2.8 3 0 0 3 3 3 2 Ion transport protein REJ PF02010.15 PVD28962.1 - 2.6e-11 43.0 0.0 6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 REJ domain PKD PF00801.20 PVD28962.1 - 2.6e-06 27.2 38.1 0.085 12.7 0.6 10.8 10 2 1 11 11 11 4 PKD domain SpuA_C PF18033.1 PVD28962.1 - 0.4 10.8 2.0 40 4.3 0.1 4.0 3 1 0 3 3 3 0 SpuA C-terminal PKD_channel PF08016.12 PVD28963.1 - 2.2e-70 237.5 22.2 2.2e-70 237.5 22.2 3.5 3 1 0 3 3 3 1 Polycystin cation channel PLAT PF01477.23 PVD28963.1 - 1.7e-15 57.6 0.0 4.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 PVD28963.1 - 2.3e-13 50.0 19.4 2.3e-13 50.0 19.4 3.4 4 0 0 4 4 4 1 Ion transport protein GPS PF01825.21 PVD28963.1 - 1.9 9.0 5.5 6.7 7.3 5.5 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif Ferritin PF00210.24 PVD28964.1 - 5e-38 130.2 0.6 5.8e-38 130.0 0.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 PVD28964.1 - 0.00032 21.1 0.1 0.0004 20.8 0.1 1.2 1 0 0 1 1 1 1 Rubrerythrin BTB_3 PF16017.5 PVD28965.1 - 1.7e-50 169.5 0.0 3.3e-50 168.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 PVD28965.1 - 0.0054 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Flot PF15975.5 PVD28966.1 - 0.26 11.5 37.5 5.1 7.3 0.3 7.6 3 1 5 8 8 8 0 Flotillin Lipocalin_2 PF08212.12 PVD28967.1 - 4.3e-13 49.4 0.0 7.3e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 PVD28967.1 - 2.4e-06 27.8 0.0 3.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PKD_channel PF08016.12 PVD28968.1 - 2.4e-73 247.3 4.6 2.4e-73 247.3 4.6 1.9 3 0 0 3 3 3 1 Polycystin cation channel PLAT PF01477.23 PVD28968.1 - 4.4e-15 56.3 0.0 9.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 PVD28968.1 - 9.6e-12 44.6 5.3 9.6e-12 44.6 5.3 2.8 4 0 0 4 4 4 1 Ion transport protein REJ PF02010.15 PVD28969.1 - 2.2e-20 72.9 0.0 8.3e-12 44.6 0.0 2.7 1 1 1 2 2 2 2 REJ domain WAP PF00095.21 PVD28969.1 - 1.3e-14 54.2 36.0 1.6e-07 31.6 18.2 3.3 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 PVD28969.1 - 3.6e-06 27.2 15.1 5.7e-05 23.4 5.1 3.8 4 0 0 4 4 4 2 Lustrin, cysteine-rich repeated domain PKD PF00801.20 PVD28969.1 - 0.00047 20.0 25.7 0.054 13.4 3.3 6.4 7 0 0 7 7 7 3 PKD domain Lustrin_cystein PF14625.6 PVD28970.1 - 1.8e-11 44.2 17.1 2.1e-07 31.2 3.6 4.4 4 1 0 4 4 4 2 Lustrin, cysteine-rich repeated domain WAP PF00095.21 PVD28970.1 - 2.9e-08 34.0 17.9 2.9e-08 34.0 17.9 4.3 4 1 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' RolB_RolC PF02027.17 PVD28970.1 - 0.031 13.9 0.0 0.074 12.7 0.0 1.6 2 0 0 2 2 2 0 RolB/RolC glucosidase family WAP PF00095.21 PVD28971.1 - 4.3e-08 33.4 17.6 4.3e-08 33.4 17.6 3.7 3 1 1 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 PVD28971.1 - 4.1e-06 27.1 5.9 4.1e-06 27.1 5.9 4.0 2 1 1 3 3 3 1 Lustrin, cysteine-rich repeated domain WAP PF00095.21 PVD28972.1 - 2.4e-08 34.2 13.7 2.4e-08 34.2 13.7 5.1 4 2 0 5 5 5 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 PVD28973.1 - 1.6e-08 34.7 15.9 1.6e-08 34.7 15.9 3.2 3 1 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 PVD28973.1 - 5e-06 26.8 5.9 5e-06 26.8 5.9 3.8 3 1 1 4 4 4 1 Lustrin, cysteine-rich repeated domain WAP PF00095.21 PVD28974.1 - 2.2e-18 66.3 52.6 3e-08 33.9 12.3 10.0 8 2 2 10 10 10 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 PVD28975.1 - 3.9e-08 33.6 12.9 3.9e-08 33.6 12.9 7.7 4 1 3 7 7 7 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' PDEase_I PF00233.19 PVD28977.1 - 4.5e-64 216.4 3.2 4e-61 206.8 0.0 2.9 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Staphylcoagulse PF04022.12 PVD28977.1 - 0.031 13.8 0.1 0.086 12.4 0.1 1.7 1 0 0 1 1 1 0 Staphylocoagulase repeat SOBP PF15279.6 PVD28978.1 - 1.1 9.8 8.2 0.64 10.6 4.4 2.2 2 1 0 2 2 2 0 Sine oculis-binding protein DUF2868 PF11067.8 PVD28979.1 - 0.92 9.0 5.0 1.3 8.5 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) TcpE PF12648.7 PVD28981.1 - 0.44 11.1 3.3 3.8 8.1 0.0 2.3 2 0 0 2 2 2 0 TcpE family PIH1 PF08190.12 PVD28984.1 - 2.1e-36 124.9 0.0 3e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 PVD28984.1 - 4.2e-18 65.6 0.0 7.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain Aldedh PF00171.22 PVD28985.1 - 1.7e-156 521.4 0.0 6.3e-114 381.0 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 PVD28985.1 - 5.7e-09 35.7 0.1 1.5e-07 31.1 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF3046 PF11248.8 PVD28986.1 - 0.0091 16.4 0.0 5.3 7.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3046) OCIA PF07051.11 PVD28986.1 - 0.023 14.7 0.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF5395 PF17373.2 PVD28986.1 - 0.082 13.6 0.4 24 5.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5395) LURAP PF14854.6 PVD28988.1 - 0.00023 21.1 0.4 0.00023 21.1 0.4 2.0 2 0 0 2 2 2 1 Leucine rich adaptor protein DHR10 PF18595.1 PVD28988.1 - 0.087 12.9 0.6 0.15 12.2 0.2 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF716 PF04819.12 PVD28989.1 - 2.8e-25 88.6 5.0 6.1e-25 87.5 5.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF716) PGA2 PF07543.12 PVD28989.1 - 0.13 12.2 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Ytp1 PF10355.9 PVD28989.1 - 0.25 10.5 4.0 0.062 12.5 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (Ytp1) Chs7 PF12271.8 PVD28989.1 - 0.34 10.3 4.9 0.49 9.7 0.3 2.1 1 1 1 2 2 2 0 Chitin synthase export chaperone NUP50 PF08911.11 PVD28990.1 - 0.54 11.0 0.0 0.54 11.0 0.0 2.7 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) SHIPPO-rpt PF07004.12 PVD28991.1 - 1.2e-13 51.2 25.9 0.0036 18.1 0.2 6.8 6 2 0 6 6 6 5 Sperm-tail PG-rich repeat WD40 PF00400.32 PVD28992.1 - 3.8e-08 33.9 2.5 9.6e-05 23.1 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD28992.1 - 0.0098 16.2 0.0 0.93 9.8 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RabGAP-TBC PF00566.18 PVD28993.1 - 5.3e-54 183.1 1.8 7.7e-54 182.6 1.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Bacillus_HBL PF05791.11 PVD28994.1 - 0.064 13.1 0.7 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Med2 PF11214.8 PVD28994.1 - 0.17 12.0 0.5 1 9.6 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 ApoA-II PF04711.13 PVD28994.1 - 0.32 11.2 1.8 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Retrotrans_gag PF03732.17 PVD28994.1 - 8.3 6.8 6.4 33 4.9 0.0 3.6 3 1 1 4 4 4 0 Retrotransposon gag protein 7tm_2 PF00002.24 PVD28995.1 - 3.7e-13 49.3 12.4 6.9e-13 48.4 12.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 PVD28995.1 - 4.5e-06 26.9 8.4 3.9e-05 23.9 8.4 2.7 1 0 0 1 1 1 1 Somatomedin B domain DUF4434 PF14488.6 PVD28996.1 - 0.0021 18.1 0.0 3.1 7.8 0.0 3.7 4 0 0 4 4 4 3 Domain of unknown function (DUF4434) GMC_oxred_N PF00732.19 PVD28997.1 - 1.5e-75 254.3 0.0 1.9e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PVD28997.1 - 4.1e-40 137.6 0.1 6.2e-40 137.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PVD28997.1 - 5.1e-05 22.5 0.2 7.9e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 PVD28997.1 - 5.4e-05 22.5 0.1 0.074 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 PVD28997.1 - 0.00041 20.0 0.2 0.004 16.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PVD28997.1 - 0.00055 20.1 0.1 0.0017 18.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PVD28997.1 - 0.00093 18.5 0.0 0.0038 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD28997.1 - 0.0022 17.3 0.1 0.11 11.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PVD28997.1 - 0.0032 16.7 0.1 0.006 15.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GMC_oxred_N PF00732.19 PVD28998.1 - 2e-74 250.6 0.0 2.6e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PVD28998.1 - 3.6e-41 141.0 0.1 5.7e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 PVD28998.1 - 5.5e-05 22.4 0.0 0.049 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 PVD28998.1 - 0.00022 20.4 0.1 0.00022 20.4 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PVD28998.1 - 0.00045 19.6 0.0 0.0036 16.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD28998.1 - 0.00055 20.1 0.3 0.0013 18.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD28998.1 - 0.0006 19.5 0.3 0.016 14.9 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PVD28998.1 - 0.0069 15.7 0.3 0.39 9.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PVD28998.1 - 0.066 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 PVD28998.1 - 0.14 10.8 0.1 0.25 10.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 PVD28999.1 - 1.2e-117 393.5 0.0 1.4e-117 393.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29000.1 - 5.7e-115 384.7 0.1 6.7e-115 384.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29001.1 - 8.7e-111 370.9 0.0 1e-110 370.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29002.1 - 4.2e-115 385.1 0.0 4.8e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.19 PVD29003.1 - 4.1e-20 72.0 0.1 9.7e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 PVD29003.1 - 2.2e-12 46.8 1.1 3.2e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 PVD29003.1 - 6.5e-05 22.7 0.3 0.00082 19.2 0.0 2.7 3 0 0 3 3 3 1 Biotin protein ligase C terminal domain MOLO1 PF17175.4 PVD29004.1 - 4.9e-19 68.6 0.0 7.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Pkinase_Tyr PF07714.17 PVD29005.1 - 1.1e-91 306.7 0.0 1.7e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 PVD29005.1 - 7.4e-53 176.9 32.5 7.8e-09 35.8 0.1 9.7 9 0 0 9 9 9 8 Fibronectin type III domain Pkinase PF00069.25 PVD29005.1 - 2.1e-38 132.2 0.0 3.5e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.5 PVD29005.1 - 5.7e-09 36.4 18.6 0.27 11.8 0.4 7.7 8 0 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 PVD29005.1 - 0.035 13.9 3.5 0.32 10.9 0.0 3.5 3 0 0 3 3 3 0 Tissue factor RSD-2 PF07547.13 PVD29005.1 - 0.13 12.8 0.2 26 5.4 0.0 2.9 2 0 0 2 2 2 0 RSD-2 N-terminal domain PDZ PF00595.24 PVD29006.1 - 1.4e-15 57.4 0.5 3.5e-15 56.1 0.5 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD29006.1 - 2.1e-06 27.5 0.1 5.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD29006.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain BBP1_C PF15272.6 PVD29006.1 - 0.12 12.1 2.9 0.27 11.1 2.9 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal NYD-SP28_assoc PF14775.6 PVD29006.1 - 0.51 10.5 7.5 2.8 8.1 0.1 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 PVD29006.1 - 0.81 9.8 4.7 0.45 10.6 0.4 2.7 2 1 1 3 3 3 0 Basic region leucine zipper YabA PF06156.13 PVD29006.1 - 1.1 9.9 6.7 8 7.2 1.2 2.8 1 1 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 PVD29006.1 - 2.1 8.9 15.6 0.76 10.3 6.7 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region KLRAQ PF10205.9 PVD29006.1 - 5.4 7.3 10.7 3.5 7.9 1.2 3.1 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein DivIC PF04977.15 PVD29006.1 - 8.8 6.2 10.4 3.4 7.5 0.4 2.9 3 1 0 3 3 3 0 Septum formation initiator RhoGAP PF00620.27 PVD29007.1 - 2e-23 82.9 0.0 3.7e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain INPP5B_PH PF16776.5 PVD29007.1 - 4.1e-23 81.7 0.1 6.9e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Exo_endo_phos PF03372.23 PVD29007.1 - 7.3e-15 55.1 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 PVD29008.1 - 7.4e-71 239.3 0.0 9.6e-70 235.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FANCAA PF15146.6 PVD29008.1 - 0.00015 21.0 0.8 0.00035 19.8 0.8 1.6 1 0 0 1 1 1 1 Fanconi anemia-associated DUF5540 PF17694.1 PVD29008.1 - 0.11 13.0 0.0 0.39 11.3 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Vg_Tdu PF07545.14 PVD29010.1 - 2.8e-19 68.6 0.2 5.1e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family FAM181 PF15238.6 PVD29010.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 FAM181 TT_ORF2 PF02957.15 PVD29011.1 - 0.088 13.7 0.0 0.15 13.0 0.0 1.4 1 1 0 1 1 1 0 TT viral ORF2 Pkinase PF00069.25 PVD29013.1 - 9.2e-20 71.1 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29013.1 - 6.7e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD29013.1 - 0.043 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.22 PVD29014.1 - 3.6e-30 103.6 15.0 3.5e-15 55.6 0.1 5.7 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD29014.1 - 0.011 15.9 0.0 0.38 10.9 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif RRM_Rrp7 PF17799.1 PVD29014.1 - 0.11 12.3 7.5 0.14 11.9 0.0 3.8 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain SASA PF03629.18 PVD29015.1 - 5.7e-15 55.6 0.0 8.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase BON PF04972.17 PVD29015.1 - 0.059 13.7 0.2 15 6.0 0.2 3.0 3 0 0 3 3 3 0 BON domain SASA PF03629.18 PVD29016.1 - 4.7e-16 59.1 0.0 6.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD29017.1 - 1.1e-14 54.7 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD29018.1 - 2.1e-15 57.0 0.0 3.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD29019.1 - 1.3e-12 47.9 0.0 2.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 PVD29020.1 - 2.3e-14 53.6 0.0 3.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Glyco_transf_64 PF09258.10 PVD29021.1 - 8.7e-76 254.4 0.1 1.4e-75 253.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 PVD29021.1 - 7.3e-36 123.9 0.0 1.2e-31 110.1 0.0 2.1 1 1 1 2 2 2 2 Exostosin family Lipase_3 PF01764.25 PVD29022.1 - 3.8e-13 49.5 0.0 9.9e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF3377 PF11857.8 PVD29023.1 - 0.22 11.4 1.9 0.5 10.3 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) LRR19-TM PF15176.6 PVD29023.1 - 0.35 10.9 0.9 0.87 9.6 0.0 2.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain T-box PF00907.22 PVD29025.1 - 6.4e-76 254.7 0.1 8.8e-76 254.3 0.1 1.2 1 0 0 1 1 1 1 T-box Mito_fiss_reg PF05308.11 PVD29026.1 - 0.099 12.7 3.8 0.097 12.7 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD29026.1 - 0.34 10.9 16.1 0.44 10.6 16.1 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD29026.1 - 2.5 7.5 11.0 3 7.2 11.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3915 PF13054.6 PVD29028.1 - 0.13 12.3 1.8 0.14 12.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) STAR_dimer PF16544.5 PVD29030.1 - 1.2e-23 82.4 0.5 2.4e-23 81.4 0.5 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 PVD29030.1 - 3.4e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 KH domain Epimerase PF01370.21 PVD29031.1 - 6.3e-46 156.8 0.0 5.2e-44 150.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD29031.1 - 2.1e-11 43.8 1.8 4e-05 23.2 0.0 2.8 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PVD29031.1 - 2e-07 30.4 0.0 2.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PVD29031.1 - 0.00012 21.4 1.2 0.0011 18.2 0.0 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PVD29031.1 - 0.13 11.4 0.1 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Acyl-CoA_dh_1 PF00441.24 PVD29032.1 - 1.2e-45 155.4 1.9 1.8e-45 154.8 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD29032.1 - 3.1e-31 108.3 0.3 6.4e-31 107.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD29032.1 - 2.9e-24 85.1 0.0 6.1e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD29032.1 - 3.5e-22 79.1 1.7 3.6e-22 79.1 0.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF525 PF04379.14 PVD29033.1 - 3.3e-21 75.3 0.0 5.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 PVD29033.1 - 1.4e-13 50.5 0.2 3.3e-13 49.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD29033.1 - 1.6e-08 34.2 0.1 3.5e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain SMI1_KNR4 PF09346.10 PVD29033.1 - 0.00029 21.2 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box_4 PF15966.5 PVD29033.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box Duffy_binding PF05424.11 PVD29033.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Duffy binding domain p450 PF00067.22 PVD29034.1 - 1e-11 44.3 0.0 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29035.1 - 8.2e-98 328.1 0.0 9.1e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Styelin PF17562.2 PVD29035.1 - 0.075 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Styelin Neurexophilin PF06312.12 PVD29036.1 - 0.0029 17.1 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 Neurexophilin Filamin PF00630.19 PVD29036.1 - 0.0082 17.0 0.0 0.016 16.0 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF4519 PF15012.6 PVD29036.1 - 0.87 9.8 4.9 1.8 8.8 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) NGF PF00243.18 PVD29037.1 - 4e-20 72.1 4.9 5.9e-20 71.6 4.9 1.2 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 PVD29037.1 - 0.046 14.2 5.0 0.074 13.6 5.0 1.3 1 0 0 1 1 1 0 Spaetzle ARID PF01388.21 PVD29038.1 - 9.4e-26 90.3 0.0 2.8e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 PVD29038.1 - 2.1e-08 34.6 0.2 6.8e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain WD40 PF00400.32 PVD29039.1 - 2.2e-16 59.9 7.9 0.00055 20.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD29039.1 - 1e-06 28.9 1.4 0.00016 21.9 0.6 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD29039.1 - 0.00014 20.6 0.2 0.49 9.0 0.3 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD29039.1 - 0.039 12.7 0.0 0.22 10.2 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like CDC37_C PF08564.10 PVD29040.1 - 2.6e-16 59.6 0.1 2.6e-16 59.6 0.1 3.9 3 2 2 5 5 5 1 Cdc37 C terminal domain CDC37_M PF08565.11 PVD29040.1 - 3e-11 43.3 9.3 1.3e-08 34.8 0.1 3.3 2 1 1 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 PVD29040.1 - 2e-07 31.9 19.6 3.7e-07 31.1 17.6 2.4 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding UBM PF14377.6 PVD29040.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Sec20 PF03908.13 PVD29040.1 - 0.16 11.9 1.2 0.41 10.6 1.2 1.7 1 0 0 1 1 1 0 Sec20 Hemagglutinin PF00509.18 PVD29040.1 - 0.29 9.5 3.0 0.15 10.4 1.1 1.4 2 0 0 2 2 2 0 Haemagglutinin V_ATPase_I PF01496.19 PVD29040.1 - 3 5.6 11.8 3.9 5.3 11.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family D5_N PF08706.11 PVD29040.1 - 3.6 7.8 8.1 43 4.4 6.8 2.5 1 1 0 1 1 1 0 D5 N terminal like TFIID_20kDa PF03847.13 PVD29041.1 - 2.9e-33 114.1 3.0 4e-33 113.7 3.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 PVD29041.1 - 9.6e-06 26.0 0.1 1.7e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD29041.1 - 1.5e-05 25.2 0.1 2.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PVD29041.1 - 4.8e-05 23.4 0.1 6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Tic110 PF16940.5 PVD29041.1 - 0.0033 16.0 0.1 0.0041 15.7 0.1 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter CENP-T_C PF15511.6 PVD29041.1 - 0.046 13.9 0.3 0.075 13.2 0.3 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 PVD29041.1 - 0.069 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF4 PF05236.14 PVD29041.1 - 0.091 12.5 1.2 0.13 12.0 0.2 1.6 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family EF-hand_11 PF08976.11 PVD29042.1 - 3.2e-76 252.9 29.4 1.7e-17 64.2 0.3 12.2 12 0 0 12 12 12 11 EF-hand domain EF-hand_7 PF13499.6 PVD29042.1 - 8e-49 164.0 63.3 2.6e-05 24.6 0.3 13.5 12 1 1 13 13 13 12 EF-hand domain pair EF-hand_1 PF00036.32 PVD29042.1 - 2.6e-40 133.0 33.4 3.1e-05 23.2 0.2 18.0 19 0 0 19 19 19 10 EF hand EF-hand_6 PF13405.6 PVD29042.1 - 2.2e-38 126.9 51.0 6.4e-05 22.6 0.5 17.4 18 0 0 18 18 17 9 EF-hand domain EF-hand_8 PF13833.6 PVD29042.1 - 1.4e-19 69.6 31.2 0.0085 15.9 0.0 13.1 12 2 2 14 14 14 8 EF-hand domain pair EF-hand_5 PF13202.6 PVD29042.1 - 2.9e-17 61.3 25.5 0.00014 21.2 0.3 10.6 13 0 0 13 13 12 3 EF hand EF-hand_9 PF14658.6 PVD29042.1 - 8.4e-09 35.6 1.8 1.8 8.9 0.0 7.5 9 0 0 9 9 9 2 EF-hand domain DUF5580 PF17743.1 PVD29042.1 - 1.3e-07 30.5 4.7 0.084 11.4 0.0 5.1 3 2 2 5 5 5 2 Family of unknown function (DUF5580) GPHH PF16905.5 PVD29042.1 - 1.5e-06 27.8 0.0 0.00014 21.5 0.0 4.1 4 0 0 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated Dockerin_1 PF00404.18 PVD29042.1 - 0.0002 21.5 0.5 0.13 12.5 0.0 4.9 5 0 0 5 5 5 1 Dockerin type I domain EF-hand_4 PF12763.7 PVD29042.1 - 0.00088 19.2 7.0 0.37 10.8 0.1 5.7 7 0 0 7 7 6 1 Cytoskeletal-regulatory complex EF hand DUF2666 PF10869.8 PVD29042.1 - 0.0039 17.4 3.8 65 3.7 0.0 6.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2666) TerB PF05099.13 PVD29042.1 - 0.027 14.4 0.5 19 5.2 0.1 3.8 2 1 1 3 3 3 0 Tellurite resistance protein TerB DUF3511 PF12023.8 PVD29042.1 - 0.028 14.3 0.3 12 5.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) RPN13_C PF16550.5 PVD29042.1 - 0.048 13.8 0.0 1.5 9.0 0.0 3.3 2 0 0 2 2 2 0 UCH-binding domain Caleosin PF05042.13 PVD29042.1 - 0.13 12.2 15.0 27 4.6 0.1 8.6 11 2 1 12 12 11 0 Caleosin related protein UPF0175 PF03683.13 PVD29042.1 - 0.16 11.7 0.8 21 4.9 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0175) ORF6N PF10543.9 PVD29042.1 - 8.9 6.6 9.1 1.4 9.1 0.1 4.2 5 0 0 5 5 4 0 ORF6N domain Glyco_hydro_99 PF16317.5 PVD29043.1 - 4.9e-106 354.7 0.2 6.1e-106 354.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 PVD29043.1 - 0.004 16.7 0.2 0.02 14.3 0.1 1.9 1 1 1 2 2 2 1 Glycosyltransferase WbsX DUF5010 PF16402.5 PVD29043.1 - 0.032 13.0 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Glyco_hydro_71 PF03659.14 PVD29043.1 - 0.049 12.4 0.4 0.067 12.0 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Isochorismatase PF00857.20 PVD29043.1 - 0.17 12.1 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Isochorismatase family CTD_bind PF04818.13 PVD29044.1 - 2.1e-16 60.5 0.3 5e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 PVD29044.1 - 3.5e-10 39.6 0.0 6.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD29044.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif CDC45 PF02724.14 PVD29044.1 - 3.4 5.8 22.8 5.8 5.1 22.8 1.3 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 PVD29044.1 - 7.2 5.3 9.9 13 4.5 9.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sod_Cu PF00080.20 PVD29045.1 - 1.2e-45 155.2 5.5 1.4e-45 154.9 5.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3713 PF12506.8 PVD29046.1 - 0.26 11.6 2.4 6.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) RNase_Zc3h12a PF11977.8 PVD29048.1 - 1.4e-63 213.3 0.0 3.4e-63 212.1 0.0 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 PVD29048.1 - 1.8e-12 47.0 0.4 4.4e-12 45.7 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 PVD29048.1 - 6.4e-05 22.7 7.3 0.00011 21.9 7.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger PRORP PF16953.5 PVD29048.1 - 0.037 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH PF00642.24 PVD29048.1 - 0.046 13.7 4.3 0.11 12.4 4.3 1.6 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PVD29048.1 - 3 8.5 8.2 5.5 7.6 8.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger p450 PF00067.22 PVD29049.1 - 3e-69 234.0 0.0 3.9e-35 121.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD29050.1 - 2.1e-37 129.0 0.0 2.6e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 PVD29051.1 - 7.1e-13 48.3 0.7 1.2e-12 47.6 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PDZ PF00595.24 PVD29053.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PWI PF01480.17 PVD29054.1 - 7.2e-28 96.7 0.1 1.3e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 PWI domain SLC35F PF06027.12 PVD29055.1 - 3.8e-98 328.7 20.8 4.6e-98 328.4 20.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 PVD29055.1 - 1.3e-14 54.5 29.5 6e-08 32.9 16.1 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PVD29055.1 - 1.1e-08 34.7 17.2 1.7e-08 34.0 17.2 1.3 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 PVD29055.1 - 1.3e-08 34.2 11.4 2.7e-08 33.2 2.3 2.3 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 PVD29055.1 - 0.0082 15.3 10.1 0.025 13.7 9.4 2.2 1 1 0 1 1 1 1 Magnesium transporter NIPA Halogen_Hydrol PF10112.9 PVD29055.1 - 2.4 8.1 5.3 0.51 10.3 0.3 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2101 PF09874.9 PVD29055.1 - 6.4 6.4 16.0 0.35 10.5 2.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) zf-C3HC4_3 PF13920.6 PVD29056.1 - 2.9e-12 46.3 8.0 2.9e-12 46.3 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 PVD29056.1 - 3.4e-06 26.8 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RanBP PF00641.18 PVD29056.1 - 0.0097 15.2 2.1 0.0097 15.2 2.1 2.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 PVD29056.1 - 0.21 11.6 12.6 2.8 8.0 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 PVD29056.1 - 0.59 10.0 15.2 0.32 10.9 6.5 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD29056.1 - 0.84 10.0 15.1 0.18 12.2 7.0 2.7 2 0 0 2 2 2 0 Ring finger domain NAD_binding_1 PF00175.21 PVD29057.1 - 1.9e-14 54.2 0.0 3.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PVD29057.1 - 4e-14 52.8 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PVD29057.1 - 0.00023 21.3 0.2 0.00056 20.1 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CS PF04969.16 PVD29057.1 - 0.15 13.1 0.6 0.57 11.2 0.6 2.1 1 1 0 1 1 1 0 CS domain DUF4713 PF15831.5 PVD29057.1 - 0.69 10.4 5.7 2 8.9 2.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Cyt-b5 PF00173.28 PVD29058.1 - 0.00063 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_6 PF12774.7 PVD29059.1 - 1.3e-161 537.1 2.0 2e-159 529.9 0.0 3.6 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD29059.1 - 2.6e-146 487.8 11.1 2.6e-146 487.8 11.1 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD29059.1 - 1.4e-103 345.7 0.1 4.1e-103 344.2 0.0 1.9 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD29059.1 - 2e-80 268.6 0.1 4.3e-77 257.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 PVD29059.1 - 1.3e-31 109.4 0.0 5.1e-31 107.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD29059.1 - 1.9e-29 102.8 4.1 3.9e-29 101.8 4.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 PVD29059.1 - 2.2e-20 72.7 0.1 1.8e-19 69.8 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PVD29059.1 - 7.4e-15 55.2 0.0 0.0025 17.8 0.0 6.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD29059.1 - 8.9e-07 29.4 0.4 0.37 11.2 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PVD29059.1 - 0.00056 20.5 0.1 0.036 14.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 PVD29059.1 - 0.0013 19.2 1.3 39 4.6 0.0 5.5 5 0 0 5 5 5 0 AAA ATPase domain AAA_30 PF13604.6 PVD29059.1 - 0.0046 16.7 0.2 2.6 7.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD29059.1 - 0.009 16.3 5.3 8.4 6.7 0.0 5.0 5 0 0 5 5 4 0 AAA domain Microtub_bd PF16796.5 PVD29059.1 - 0.017 15.1 0.0 0.098 12.6 0.0 2.4 1 0 0 1 1 1 0 Microtubule binding ResIII PF04851.15 PVD29059.1 - 0.031 14.3 0.4 0.64 10.0 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD29059.1 - 0.048 13.4 0.1 18 5.0 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 PVD29059.1 - 0.091 11.8 1.3 6.9 5.6 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 PVD29059.1 - 0.1 13.0 0.0 18 5.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase PhoH PF02562.16 PVD29059.1 - 0.13 11.7 0.0 0.13 11.7 0.0 3.1 4 0 0 4 4 3 0 PhoH-like protein Methyltransf_23 PF13489.6 PVD29059.1 - 0.14 12.0 0.0 0.58 10.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain CusF_Ec PF11604.8 PVD29059.1 - 0.16 12.0 0.2 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF DUF853 PF05872.12 PVD29059.1 - 0.19 10.3 1.6 17 3.8 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) FUSC PF04632.12 PVD29059.1 - 0.85 8.1 4.6 2 6.9 4.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Dynein_C PF18199.1 PVD29060.1 - 2.2e-100 335.8 0.4 4.7e-78 262.5 0.0 2.4 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD29060.1 - 3.5e-68 229.0 1.2 1.6e-66 223.6 0.2 2.9 2 1 1 3 3 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PVD29060.1 - 2e-58 196.8 0.0 3.5e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD29060.1 - 3.3e-46 156.3 0.0 2.5e-45 153.4 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD29060.1 - 7.8e-13 48.2 1.1 1.3e-12 47.4 1.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF812 PF05667.11 PVD29060.1 - 0.0047 15.9 1.4 0.0092 14.9 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 PVD29060.1 - 0.0083 15.0 1.2 0.0083 15.0 1.2 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 PVD29060.1 - 0.018 14.8 2.2 0.033 13.9 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1064 PF06356.11 PVD29060.1 - 0.17 12.2 0.1 2 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) ATG16 PF08614.11 PVD29060.1 - 0.32 11.2 5.7 0.67 10.1 5.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 PVD29060.1 - 0.66 10.0 8.5 0.76 9.8 6.8 2.0 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain Mod_r PF07200.13 PVD29060.1 - 0.7 10.0 4.5 0.23 11.5 0.9 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Sec34 PF04136.15 PVD29060.1 - 1 9.2 3.3 0.72 9.7 0.7 1.9 2 0 0 2 2 2 0 Sec34-like family GAS PF13851.6 PVD29060.1 - 3.6 6.9 8.9 0.18 11.1 3.0 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 PVD29060.1 - 4.5 6.5 6.5 0.28 10.5 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 PVD29060.1 - 4.5 7.6 6.7 6.6 7.0 0.7 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 PVD29060.1 - 4.6 7.7 11.6 7.5 7.1 2.9 3.0 2 1 0 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 PVD29060.1 - 6.2 7.2 7.9 0.29 11.5 1.9 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 PVD29060.1 - 8.5 6.5 10.3 3 8.0 4.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_6 PF12774.7 PVD29061.1 - 2.9e-163 542.5 0.2 9.7e-160 530.9 0.0 3.2 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD29061.1 - 2.1e-142 474.9 10.5 2.1e-142 474.9 10.5 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD29061.1 - 1.7e-100 335.7 1.1 6.8e-100 333.7 0.0 2.8 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PVD29061.1 - 4.9e-98 328.1 0.1 2.1e-96 322.8 0.0 3.6 2 1 1 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD29061.1 - 3.8e-91 304.1 0.1 9.9e-89 296.2 0.0 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD29061.1 - 8.3e-79 263.3 0.1 1.4e-74 249.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD29061.1 - 3.7e-56 189.4 0.1 1.2e-55 187.8 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD29061.1 - 7.1e-48 163.4 11.9 1.3e-47 162.5 11.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD29061.1 - 2.4e-42 143.8 0.0 2.6e-40 137.2 0.2 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD29061.1 - 1.3e-28 99.7 0.9 5.4e-28 97.7 0.1 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD29061.1 - 1.3e-19 70.2 0.0 8.1e-19 67.7 0.0 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD29061.1 - 1.7e-18 67.0 0.0 0.00012 22.1 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD29061.1 - 1.3e-07 32.1 0.2 0.52 10.7 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD29061.1 - 2.1e-06 28.0 1.0 0.06 13.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 PVD29061.1 - 1.9e-05 25.2 0.1 0.049 14.2 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 PVD29061.1 - 5.9e-05 23.5 2.5 0.67 10.3 0.0 4.7 5 0 0 5 5 4 1 AAA ATPase domain Mg_chelatase PF01078.21 PVD29061.1 - 0.00012 21.6 0.1 0.43 9.9 0.0 3.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 PVD29061.1 - 0.0011 18.2 0.3 0.13 11.3 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 PVD29061.1 - 0.0013 18.5 4.1 1.1 8.9 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PVD29061.1 - 0.0049 17.0 0.5 17 5.5 0.0 4.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PVD29061.1 - 0.019 15.4 2.0 27 5.2 0.0 4.5 5 0 0 5 5 3 0 RNA helicase ABC_tran PF00005.27 PVD29061.1 - 0.038 14.5 0.0 2.5 8.6 0.0 3.4 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.26 PVD29061.1 - 0.054 13.2 0.2 0.56 9.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Laminin_II PF06009.12 PVD29061.1 - 0.1 12.6 11.6 2.4 8.2 0.2 4.1 3 0 0 3 3 3 0 Laminin Domain II TsaE PF02367.17 PVD29061.1 - 0.12 12.4 1.9 18 5.4 0.1 3.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 PVD29061.1 - 0.21 10.2 3.0 15 4.0 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 PVD29061.1 - 0.24 11.7 4.2 22 5.4 0.1 4.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 PVD29061.1 - 0.27 10.7 2.9 3.9 6.9 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein SRP54 PF00448.22 PVD29061.1 - 1.9 8.1 6.1 14 5.3 0.0 3.8 3 1 1 4 4 4 0 SRP54-type protein, GTPase domain T3SSipB PF16535.5 PVD29061.1 - 3.5 8.1 12.0 0.89 10.0 4.1 3.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB Acyl-CoA_dh_2 PF08028.11 PVD29061.1 - 7.3 6.9 6.3 20 5.4 6.3 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ResIII PF04851.15 PVD29061.1 - 7.6 6.5 8.6 1.2 9.1 0.0 3.6 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit Fibrinogen_C PF00147.18 PVD29062.1 - 1.2e-15 57.9 2.6 4.8e-13 49.4 1.4 2.3 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD29062.1 - 0.0062 16.5 2.6 0.019 14.9 2.6 1.9 1 0 0 1 1 1 1 PAN domain EGF_Tenascin PF18720.1 PVD29062.1 - 0.019 15.0 1.8 0.019 15.0 1.8 2.3 2 0 0 2 2 2 0 Tenascin EGF domain Laminin_EGF PF00053.24 PVD29062.1 - 4.2 7.6 8.0 6.1 7.1 3.4 2.7 2 0 0 2 2 2 0 Laminin EGF domain LRR_6 PF13516.6 PVD29063.1 - 1.8e-21 74.3 15.7 0.0009 19.1 0.0 8.5 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 PVD29063.1 - 0.00028 21.2 10.8 0.018 15.4 0.2 4.7 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD29063.1 - 0.0019 18.5 11.8 10 7.1 0.0 6.9 9 0 0 9 9 9 1 Leucine Rich Repeat EF-hand_1 PF00036.32 PVD29063.1 - 0.0028 17.1 0.0 0.051 13.2 0.0 2.7 2 0 0 2 2 2 1 EF hand LRR_8 PF13855.6 PVD29063.1 - 0.092 12.5 13.3 4.6 7.1 0.2 5.6 4 2 0 4 4 4 0 Leucine rich repeat TrbE PF11100.8 PVD29063.1 - 0.24 11.7 0.5 0.53 10.5 0.5 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbE tRNA-synt_1b PF00579.25 PVD29064.1 - 1.5e-26 93.4 0.0 2.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EphA2_TM PF14575.6 PVD29065.1 - 0.00076 20.3 0.2 0.0063 17.4 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PVD29065.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 1.9 2 0 0 2 2 2 1 Transmembrane protein 51 SIT PF15330.6 PVD29065.1 - 0.0029 18.0 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Glycophorin_A PF01102.18 PVD29065.1 - 0.0079 16.4 3.8 0.0079 16.4 3.8 3.1 1 1 2 3 3 2 1 Glycophorin A TMEM132D_C PF15706.5 PVD29065.1 - 0.0084 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Plasmodium_Vir PF05795.11 PVD29065.1 - 0.012 15.1 2.8 0.034 13.6 2.8 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Orf78 PF06024.12 PVD29065.1 - 0.012 15.9 0.2 0.036 14.4 0.2 1.8 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 PVD29065.1 - 0.081 12.8 29.1 51 3.7 29.1 3.2 1 1 0 1 1 1 0 TMEM154 protein family Peptidase_M56 PF05569.11 PVD29065.1 - 0.14 11.4 0.3 0.26 10.5 0.3 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 RIFIN PF02009.16 PVD29065.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 PVD29065.1 - 0.47 9.6 23.6 0.77 8.9 23.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Adeno_E3_CR2 PF02439.15 PVD29065.1 - 0.72 9.7 3.5 1.4 8.7 3.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1180 PF06679.12 PVD29065.1 - 3.9 7.9 20.9 36 4.7 20.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 PVD29068.1 - 0.044 13.2 7.0 0.074 12.5 7.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 PVD29068.1 - 0.073 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3042 PF11240.8 PVD29068.1 - 0.083 12.9 1.7 0.15 12.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Mid2 PF04478.12 PVD29068.1 - 0.11 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 PVD29068.1 - 0.11 13.4 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 PVD29068.1 - 0.23 10.3 1.1 0.31 9.8 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Hamartin PF04388.12 PVD29069.1 - 0.22 10.2 6.2 0.23 10.1 6.2 1.1 1 0 0 1 1 1 0 Hamartin protein Pertactin PF03212.14 PVD29069.1 - 0.27 11.2 2.3 0.83 9.6 0.8 2.5 2 1 0 2 2 2 0 Pertactin RPS31 PF17067.5 PVD29069.1 - 2.6 8.3 9.5 5.5 7.2 8.9 1.9 2 0 0 2 2 2 0 Ribosomal protein S31e Kazal_1 PF00050.21 PVD29071.1 - 1e-25 89.5 30.5 2.3e-09 37.1 8.1 3.7 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PVD29071.1 - 3.7e-21 75.0 34.9 7.7e-08 32.3 2.8 4.0 4 2 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD29072.1 - 7.9e-133 432.4 224.7 4.8e-09 36.1 7.8 18.6 5 4 13 18 18 18 18 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PVD29072.1 - 3e-102 334.6 240.3 2.7e-07 30.6 6.8 18.8 17 1 1 18 18 18 18 Kazal-type serine protease inhibitor domain Wtap PF17098.5 PVD29073.1 - 3.8e-62 208.8 16.4 3.8e-62 208.8 16.4 2.5 1 1 1 2 2 2 1 WTAP/Mum2p family YabA PF06156.13 PVD29073.1 - 0.00043 20.9 1.7 0.00043 20.9 1.7 3.7 1 1 2 3 3 3 1 Initiation control protein YabA KxDL PF10241.9 PVD29073.1 - 0.0099 16.1 3.9 0.0099 16.1 3.9 4.6 3 2 2 5 5 5 1 Uncharacterized conserved protein T2SSF PF00482.23 PVD29073.1 - 0.034 14.1 2.1 6.4 6.8 0.0 2.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Bcr-Abl_Oligo PF09036.10 PVD29073.1 - 0.35 10.9 11.1 0.35 10.9 0.4 3.6 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain AAA_13 PF13166.6 PVD29073.1 - 0.54 8.8 15.7 0.86 8.2 15.7 1.4 1 0 0 1 1 1 0 AAA domain DUF5082 PF16888.5 PVD29073.1 - 0.61 10.4 13.5 0.27 11.5 7.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF3018 PF11455.8 PVD29073.1 - 0.69 9.9 5.1 9.6 6.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) ADIP PF11559.8 PVD29073.1 - 1.6 8.8 29.4 0.28 11.3 3.7 3.6 1 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 PVD29073.1 - 5.4 7.6 33.5 1.3e+02 3.1 17.7 3.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 PVD29073.1 - 8.2 6.5 16.9 0.58 10.2 4.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Sod_Fe_C PF02777.18 PVD29074.1 - 1.4e-35 121.6 0.0 2.9e-35 120.5 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PVD29074.1 - 3.9e-33 113.8 2.2 7.3e-33 112.9 2.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribosomal_L44 PF00935.19 PVD29075.1 - 3e-37 127.0 11.7 5.5e-37 126.1 11.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 SMAP PF15477.6 PVD29076.1 - 2.8e-07 31.4 0.2 2.8e-07 31.4 0.2 1.6 2 0 0 2 2 2 1 Small acidic protein family Merozoite_SPAM PF07133.11 PVD29077.1 - 0.024 14.7 21.3 0.024 14.6 21.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RNA_polI_A34 PF08208.11 PVD29077.1 - 0.26 11.3 16.7 0.3 11.2 16.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 PVD29077.1 - 5.4 5.2 13.8 6 5.0 13.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PVD29077.1 - 9.1 4.9 9.8 9.3 4.9 9.8 1.0 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 PVD29078.1 - 1.1e-80 270.8 0.5 1.6e-80 270.3 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29078.1 - 5.9e-48 163.4 0.3 8.4e-48 162.9 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD29078.1 - 3.8e-07 29.7 0.1 7.5e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 PVD29078.1 - 2.6e-05 23.9 0.3 4.7e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PVD29078.1 - 0.00011 21.1 0.0 0.00011 21.1 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 PVD29078.1 - 0.00013 21.4 0.1 0.00021 20.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3504 PF12012.8 PVD29078.1 - 0.00094 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) YrbL-PhoP_reg PF10707.9 PVD29078.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 PVD29078.1 - 2.3 7.1 6.5 0.077 11.9 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 PVD29079.1 - 1.7e-34 119.4 2.1 2e-34 119.2 2.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29079.1 - 8.4e-22 77.7 0.9 1e-21 77.4 0.9 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GrpE PF01025.19 PVD29080.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 GrpE UPF0302 PF08864.10 PVD29080.1 - 0.089 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 UPF0302 domain Mid2 PF04478.12 PVD29080.1 - 0.22 11.4 4.2 0.43 10.4 4.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.6 PVD29080.1 - 0.48 10.6 12.3 0.056 13.7 7.3 1.9 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Cyt_bd_oxida_II PF02322.15 PVD29080.1 - 0.67 9.3 8.6 0.86 8.9 8.6 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF4389 PF14333.6 PVD29080.1 - 0.95 9.4 8.8 2 8.4 8.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) TMEM192 PF14802.6 PVD29080.1 - 1.8 7.6 9.1 4.3 6.3 9.2 1.5 2 0 0 2 2 2 0 TMEM192 family DUF2681 PF10883.8 PVD29080.1 - 4.6 7.7 8.4 7.5 7.0 5.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DAGK_acc PF00609.19 PVD29081.1 - 5.7e-46 156.8 0.0 9.5e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PVD29081.1 - 2.8e-26 91.6 0.0 6.7e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PVD29081.1 - 5.1e-14 51.9 19.4 1.3e-10 41.0 12.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 PVD29081.1 - 2.4e-13 50.4 0.2 5.1e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD29081.1 - 7.6e-12 45.2 0.1 5e-05 23.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD29081.1 - 7.5e-10 38.8 0.2 0.00016 22.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PVD29081.1 - 7.6e-09 35.9 0.1 1e-05 26.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29081.1 - 2.6e-08 33.5 0.1 0.00039 20.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_1 PF14446.6 PVD29081.1 - 1.4 8.9 11.5 0.021 14.7 2.1 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 bZIP_1 PF00170.21 PVD29082.1 - 7.5 6.7 8.7 8.8 6.5 0.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 PVD29083.1 - 2.5e-06 28.0 1.4 6.3e-06 26.7 1.4 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region PRKG1_interact PF15898.5 PVD29083.1 - 5.5e-05 24.0 14.0 5.5e-05 24.0 14.0 3.1 3 1 0 3 3 2 1 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 PVD29083.1 - 0.00091 19.1 10.3 0.0018 18.1 10.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Csm1_N PF18504.1 PVD29083.1 - 0.0018 18.6 10.7 0.0036 17.6 10.0 1.9 1 1 0 1 1 1 1 Csm1 N-terminal domain SHE3 PF17078.5 PVD29083.1 - 0.0027 17.5 10.2 0.0052 16.5 10.2 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 PVD29083.1 - 0.032 14.3 15.2 0.088 12.8 15.2 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3287 PF11690.8 PVD29083.1 - 0.033 13.9 0.6 0.088 12.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF812 PF05667.11 PVD29083.1 - 0.11 11.3 12.6 0.026 13.4 8.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Bcr-Abl_Oligo PF09036.10 PVD29083.1 - 0.13 12.3 1.9 0.29 11.2 1.9 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain GPS2_interact PF15784.5 PVD29083.1 - 0.13 12.7 7.3 0.53 10.8 7.3 2.1 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Prominin PF05478.11 PVD29083.1 - 0.22 9.4 4.5 0.28 9.1 4.5 1.1 1 0 0 1 1 1 0 Prominin DUF2730 PF10805.8 PVD29083.1 - 1.2 9.3 5.4 2.4 8.3 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ADIP PF11559.8 PVD29083.1 - 1.6 8.8 15.2 4 7.5 15.2 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NRBF2 PF08961.10 PVD29083.1 - 1.9 8.1 19.7 2.9 7.4 8.5 2.9 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 PVD29083.1 - 1.9 8.6 14.7 0.31 11.1 10.6 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2205 PF10224.9 PVD29083.1 - 2.3 8.3 9.7 5.4 7.1 9.7 1.6 1 0 0 1 1 1 0 Short coiled-coil protein FemAB PF02388.16 PVD29083.1 - 2.8 6.7 5.8 4.9 5.9 5.8 1.3 1 0 0 1 1 1 0 FemAB family ZapB PF06005.12 PVD29083.1 - 4.1 7.9 20.4 0.45 11.0 2.9 2.5 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 PVD29083.1 - 4.8 5.0 5.3 7.9 4.3 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 PVD29083.1 - 5.9 6.7 18.4 4.3 7.2 5.2 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 PVD29083.1 - 8.9 6.4 7.1 16 5.6 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 PVD29084.1 - 3.9e-33 113.9 3.4 6.7e-18 65.1 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29084.1 - 6e-32 109.6 4.3 2.1e-14 53.7 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29084.1 - 4.6e-29 100.1 12.8 3.3e-13 49.6 0.5 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD29084.1 - 3e-26 90.7 9.5 6.5e-05 23.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PVD29084.1 - 7.9e-26 87.3 2.1 2.7e-06 27.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat PRKG1_interact PF15898.5 PVD29084.1 - 1.5e-21 77.2 18.4 1.5e-21 77.2 18.4 5.8 6 1 0 6 6 6 1 cGMP-dependent protein kinase interacting domain Pyr_redox PF00070.27 PVD29084.1 - 0.08 13.5 0.5 0.62 10.7 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nitroreductase PF00881.24 PVD29084.1 - 0.1 12.7 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Nitroreductase family DUF2408 PF10303.9 PVD29084.1 - 0.41 11.2 9.6 0.18 12.4 3.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NYD-SP28_assoc PF14775.6 PVD29084.1 - 0.41 10.8 4.7 0.63 10.2 3.6 2.0 1 1 0 1 1 1 0 Sperm tail C-terminal domain Globin PF00042.22 PVD29085.1 - 6.6e-18 65.3 0.0 1.2e-17 64.5 0.0 1.4 2 0 0 2 2 2 1 Globin E1_DerP2_DerF2 PF02221.15 PVD29086.1 - 6.2e-12 46.1 0.0 7.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ML domain Anoctamin PF04547.12 PVD29087.1 - 5e-154 513.4 18.1 6e-154 513.2 18.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PVD29087.1 - 1.3e-66 224.6 0.1 2.2e-66 223.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 PVD29087.1 - 1.4 7.6 10.2 0.24 10.1 0.4 2.8 2 2 0 2 2 2 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 PVD29088.1 - 1.3e-35 123.0 19.6 1.9e-35 122.5 19.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4078 PF13300.6 PVD29088.1 - 1.9e-24 85.8 5.9 1.9e-24 85.8 5.9 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) Tctex-1 PF03645.13 PVD29089.1 - 1.1e-25 89.8 0.5 1.3e-25 89.6 0.5 1.1 1 0 0 1 1 1 1 Tctex-1 family RNase_J_C PF17770.1 PVD29089.1 - 0.072 14.1 0.0 0.21 12.7 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain p450 PF00067.22 PVD29090.1 - 4.3e-36 124.7 0.0 5.2e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29091.1 - 1.9e-23 83.0 0.0 2.3e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metal_resist PF13801.6 PVD29091.1 - 0.088 13.0 0.5 0.13 12.5 0.5 1.2 1 0 0 1 1 1 0 Heavy-metal resistance p450 PF00067.22 PVD29092.1 - 1.2e-11 44.1 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29093.1 - 7.6e-14 51.3 0.0 8.9e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29094.1 - 2.1e-13 49.8 0.0 9.3e-11 41.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD29095.1 - 1.8e-23 83.0 0.0 2.2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29096.1 - 1.4e-11 43.8 0.0 1.7e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUSC PF04632.12 PVD29096.1 - 0.13 10.8 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family p450 PF00067.22 PVD29097.1 - 1.3e-18 67.0 0.0 1.5e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29098.1 - 1.9e-99 333.5 0.0 2.1e-35 122.4 0.0 3.4 3 1 0 3 3 3 3 Cytochrome P450 DUF1495 PF07381.11 PVD29098.1 - 1.1e-05 25.2 0.2 0.46 10.3 0.0 3.4 3 0 0 3 3 3 1 Winged helix DNA-binding domain (DUF1495) ThiS-like PF14453.6 PVD29098.1 - 0.00017 21.5 0.0 8.3 6.5 0.0 3.6 3 0 0 3 3 3 1 ThiS-like ubiquitin SIR4_SID PF16991.5 PVD29098.1 - 0.00043 20.4 8.1 2.5 8.1 0.2 3.8 4 0 0 4 4 4 3 Sir4 SID domain TPP_enzyme_M PF00205.22 PVD29098.1 - 0.0016 18.2 0.0 4.3 7.1 0.0 3.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Sigma70_r1_2 PF00140.20 PVD29098.1 - 0.02 14.9 2.2 13 5.9 0.0 4.0 4 0 0 4 4 4 0 Sigma-70 factor, region 1.2 PRA-PH PF01503.17 PVD29098.1 - 0.039 14.4 0.3 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase NIBRIN_BRCT_II PF16508.5 PVD29098.1 - 0.056 13.8 1.1 4.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein FAD_binding_3 PF01494.19 PVD29098.1 - 0.079 12.2 0.1 7.1 5.8 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain tRNA_synt_1c_R1 PF04558.15 PVD29098.1 - 0.083 12.9 0.1 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF1378 PF07125.11 PVD29098.1 - 0.098 12.8 0.4 72 3.7 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1378) DUF5588 PF17826.1 PVD29098.1 - 0.13 11.1 0.6 10 4.9 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5588) MAS20 PF02064.15 PVD29098.1 - 0.16 12.0 0.1 33 4.6 0.0 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3666 PF12408.8 PVD29098.1 - 0.35 10.1 2.8 3.6 6.9 0.2 3.5 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase DUF347 PF03988.12 PVD29098.1 - 2.2 8.5 5.9 65 3.8 0.3 3.4 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) p450 PF00067.22 PVD29099.1 - 1.6e-68 231.6 0.0 1.2e-34 119.9 0.0 4.3 3 2 1 4 4 4 4 Cytochrome P450 ThiS-like PF14453.6 PVD29099.1 - 0.0062 16.5 0.1 11 6.1 0.0 3.3 3 0 0 3 3 3 2 ThiS-like ubiquitin DUF1378 PF07125.11 PVD29099.1 - 0.0065 16.6 1.6 25 5.1 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1378) HBD PF18534.1 PVD29099.1 - 0.0093 16.1 0.0 7.8 6.7 0.0 3.5 4 0 0 4 4 4 1 Helical bundle domain DUF2281 PF10047.9 PVD29099.1 - 0.042 14.5 0.4 7.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) PRA-PH PF01503.17 PVD29099.1 - 0.1 13.0 0.3 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF347 PF03988.12 PVD29099.1 - 1.8 8.8 11.4 24 5.2 0.4 3.4 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Antimicrobial22 PF16047.5 PVD29099.1 - 2.8 7.9 4.4 65 3.5 0.1 3.3 3 0 0 3 3 3 0 Frog antimicrobial peptide p450 PF00067.22 PVD29100.1 - 1.2e-28 100.1 0.1 6.2e-28 97.7 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29101.1 - 1.3e-35 123.1 0.0 1.6e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Taeniidae_ag PF05596.11 PVD29101.1 - 0.36 10.8 3.4 3.4 7.7 0.2 3.4 3 1 1 4 4 4 0 Taeniidae antigen p450 PF00067.22 PVD29103.1 - 6.3e-22 78.0 0.0 7.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF815 PF05673.13 PVD29103.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) p450 PF00067.22 PVD29104.1 - 1.1e-26 93.6 0.0 1.3e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.27 PVD29105.1 - 3.2e-13 49.7 0.0 3.6e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 PVD29106.1 - 1e-17 64.0 0.1 6.1e-17 61.5 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29107.1 - 1.5e-15 57.0 0.0 1.7e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29108.1 - 2.8e-11 42.8 0.0 3.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metal_resist PF13801.6 PVD29108.1 - 0.16 12.1 0.4 0.21 11.8 0.4 1.1 1 0 0 1 1 1 0 Heavy-metal resistance p450 PF00067.22 PVD29109.1 - 1.4e-22 80.1 0.0 1.6e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29110.1 - 6.7e-11 41.6 0.0 7.1e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29111.1 - 8.3e-10 38.0 0.0 8.4e-10 38.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29112.1 - 6.8e-12 44.9 0.0 8.2e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29113.1 - 6.4e-12 45.0 0.0 7.6e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29114.1 - 7.5e-25 87.6 0.0 8.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29115.1 - 1.5e-76 258.0 0.0 3.3e-37 128.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SIR4_SID PF16991.5 PVD29115.1 - 0.0063 16.6 1.7 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 Sir4 SID domain HBD PF18534.1 PVD29115.1 - 0.0094 16.1 0.3 12 6.1 0.0 3.3 4 0 0 4 4 4 2 Helical bundle domain DUF5588 PF17826.1 PVD29115.1 - 0.016 14.1 0.5 4.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Sigma54_activat PF00158.26 PVD29115.1 - 0.017 14.9 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Asp23 PF03780.13 PVD29115.1 - 0.065 13.7 0.3 10 6.6 0.0 2.3 2 0 0 2 2 2 0 Asp23 family, cell envelope-related function PRA-PH PF01503.17 PVD29115.1 - 0.11 12.9 0.0 26 5.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DNA_pol_B_exo2 PF10108.9 PVD29115.1 - 0.12 12.1 0.1 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ParD PF09386.10 PVD29115.1 - 0.19 12.1 0.1 28 5.2 0.0 2.5 2 0 0 2 2 2 0 Antitoxin ParD p450 PF00067.22 PVD29116.1 - 3.5e-37 128.2 0.0 4.3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2963 PF11178.8 PVD29116.1 - 4.3 7.1 6.6 15 5.4 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) p450 PF00067.22 PVD29117.1 - 2.9e-33 115.3 0.0 3.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29118.1 - 2.7e-12 46.2 0.1 3.3e-12 45.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4611 PF15387.6 PVD29118.1 - 9.5e-05 22.5 0.1 0.00047 20.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) DB_JBP1 PF18526.1 PVD29118.1 - 0.059 13.3 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain Vinculin PF01044.19 PVD29118.1 - 0.2 9.8 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Vinculin family BIR PF00653.21 PVD29120.1 - 1.4e-25 89.7 10.6 7.1e-20 71.4 0.4 3.3 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD29120.1 - 3e-12 46.2 9.0 3e-12 46.2 9.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD29120.1 - 0.00044 20.0 8.2 0.0019 18.1 8.2 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 PVD29120.1 - 0.28 11.6 6.2 0.74 10.2 6.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_UBOX PF13445.6 PVD29120.1 - 0.69 10.0 3.6 2.6 8.2 3.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC PF07967.13 PVD29120.1 - 1.5 8.8 5.1 2.2 8.3 0.0 3.1 3 1 0 3 3 3 0 C3HC zinc finger-like HSP20 PF00011.21 PVD29121.1 - 3.6e-26 91.3 0.2 4.4e-26 91.0 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD29121.1 - 4.4e-05 23.0 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Cupredoxin_1 PF13473.6 PVD29121.1 - 0.049 13.8 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain HSP20 PF00011.21 PVD29122.1 - 1.3e-26 92.7 0.4 1.6e-26 92.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD29122.1 - 1.5e-06 27.6 0.1 3.5e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Crystallin PF00525.18 PVD29122.1 - 6.2e-05 23.1 0.1 0.0001 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal Cupredoxin_1 PF13473.6 PVD29122.1 - 0.069 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain HSP20 PF00011.21 PVD29123.1 - 1.3e-28 99.2 0.7 1.6e-28 98.9 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD29123.1 - 9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Crystallin PF00525.18 PVD29123.1 - 0.055 13.6 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal HSP20 PF00011.21 PVD29124.1 - 8.4e-27 93.3 0.1 1e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD29124.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 PVD29125.1 - 1.4e-27 95.8 0.3 1.7e-27 95.6 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 PVD29125.1 - 2.9e-05 24.1 0.1 4.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 PVD29125.1 - 0.0043 16.6 0.0 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA MAP7 PF05672.11 PVD29126.1 - 2.4e-19 69.6 73.7 2.4e-19 69.6 73.7 3.6 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family COesterase PF00135.28 PVD29127.1 - 6.9e-20 71.4 0.0 7.7e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 PVD29128.1 - 6.9e-73 246.3 0.0 8.4e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD29128.1 - 1.2e-08 35.1 0.8 1.6e-07 31.4 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 PVD29128.1 - 0.049 12.5 0.1 0.1 11.5 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme E1_DerP2_DerF2 PF02221.15 PVD29129.1 - 4.2e-27 95.2 1.0 2.7e-13 50.5 0.4 2.5 2 1 0 2 2 2 2 ML domain DUF1091 PF06477.13 PVD29129.1 - 3.5e-07 30.6 0.4 0.043 14.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1091) Nepo_coat PF03391.15 PVD29129.1 - 0.022 14.2 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Nepovirus coat protein, central domain Mo-nitro_C PF06967.11 PVD29129.1 - 0.073 13.0 3.0 2.8 8.0 0.6 2.5 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Defensin_4 PF07936.12 PVD29129.1 - 0.26 11.2 3.4 9.9 6.1 0.1 3.4 3 0 0 3 3 3 0 Potassium-channel blocking toxin E1_DerP2_DerF2 PF02221.15 PVD29130.1 - 1.8e-07 31.7 1.8 2.9e-07 31.0 0.1 2.1 2 1 0 2 2 2 1 ML domain MG4 PF17789.1 PVD29130.1 - 0.032 14.4 0.4 0.095 12.9 0.4 1.7 1 0 0 1 1 1 0 Macroglobulin domain MG4 CGGC PF08821.11 PVD29130.1 - 0.17 12.1 1.7 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 CGGC domain DnaJ PF00226.31 PVD29132.1 - 3.3e-14 52.8 0.2 3.3e-14 52.8 0.2 2.8 2 1 0 2 2 2 1 DnaJ domain Carn_acyltransf PF00755.20 PVD29135.1 - 2.3e-198 660.5 0.0 3e-198 660.2 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tmp39 PF10271.9 PVD29135.1 - 3.4e-58 197.7 0.2 6.3e-58 196.8 0.2 1.3 1 0 0 1 1 1 1 Putative transmembrane protein CPT_N PF16484.5 PVD29135.1 - 3.8e-23 81.2 0.2 8.4e-23 80.1 0.2 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus DUF3558 PF12079.8 PVD29135.1 - 0.00017 21.6 0.3 0.00031 20.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) HRM PF02793.22 PVD29136.1 - 1.8e-08 34.5 0.1 4.2e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 PVD29137.1 - 2.6e-30 105.5 30.7 4e-28 98.4 30.7 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 PVD29137.1 - 3.9e-11 43.3 3.8 1.1e-10 41.8 3.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF485 PF04341.12 PVD29137.1 - 4.7 7.2 16.8 0.25 11.3 8.2 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF485 LapA_dom PF06305.11 PVD29137.1 - 7.6 6.4 8.8 12 5.8 0.5 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Npa1 PF11707.8 PVD29138.1 - 3.2e-46 158.3 5.8 3.2e-46 158.3 5.8 2.2 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 PVD29138.1 - 6.8e-44 149.9 0.6 6.8e-44 149.9 0.6 2.9 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Snf7 PF03357.21 PVD29139.1 - 1.1e-09 38.1 8.0 1.1e-09 38.1 8.0 1.4 2 0 0 2 2 2 1 Snf7 DMSP_lyase PF16867.5 PVD29139.1 - 0.2 11.3 1.0 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase DUF1664 PF07889.12 PVD29139.1 - 0.28 11.2 5.4 0.082 13.0 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) M20_dimer PF07687.14 PVD29140.1 - 1.2e-09 38.0 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 PVD29140.1 - 3.1e-05 23.8 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PVD29141.1 - 4.5e-11 42.6 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 PVD29141.1 - 4.2e-05 23.3 0.0 6.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 p450 PF00067.22 PVD29142.1 - 1.5e-108 363.5 0.0 1.7e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29143.1 - 2.7e-11 42.9 0.0 3.1e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29144.1 - 1.6e-11 43.6 0.0 1.9e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29145.1 - 3e-12 46.0 0.0 3.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD29146.1 - 2.1e-09 36.6 0.1 5.9e-09 35.2 0.0 1.5 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD29147.1 - 2.2e-19 69.6 0.0 3.9e-19 68.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb2_6 PF00562.28 PVD29148.1 - 2.1e-122 408.9 0.0 3.2e-122 408.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PVD29148.1 - 6.5e-56 189.1 0.3 1e-55 188.5 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 PVD29148.1 - 3.8e-35 120.1 0.4 1e-34 118.8 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 PVD29148.1 - 9.1e-29 99.5 1.4 2e-28 98.4 1.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 PVD29148.1 - 6.7e-26 91.1 0.3 1.4e-25 90.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 PVD29148.1 - 4.9e-21 74.7 0.1 1.7e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 PVD29148.1 - 3.2e-12 46.8 1.3 1.1e-11 45.1 1.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N_2 PF13602.6 PVD29149.1 - 8.5e-22 78.6 0.0 1.4e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PVD29149.1 - 8.5e-14 51.7 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD29149.1 - 8.6e-09 35.3 0.0 3.9e-08 33.1 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAM76 PF16046.5 PVD29150.1 - 3.4e-80 269.6 18.2 4.1e-80 269.3 18.2 1.0 1 0 0 1 1 1 1 FAM76 protein MPS2 PF17060.5 PVD29150.1 - 0.0051 16.1 2.7 0.0072 15.6 2.7 1.4 1 0 0 1 1 1 1 Monopolar spindle protein 2 KASH_CCD PF14662.6 PVD29150.1 - 0.022 14.6 16.7 0.22 11.3 6.4 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CC2-LZ PF16516.5 PVD29150.1 - 0.032 14.6 8.9 0.032 14.6 8.9 2.3 2 1 1 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YgbA_NO PF11756.8 PVD29150.1 - 0.042 14.2 7.9 0.12 12.8 7.9 1.8 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter DUF1677 PF07911.13 PVD29150.1 - 0.044 14.2 0.2 0.044 14.2 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) Jnk-SapK_ap_N PF09744.9 PVD29150.1 - 0.045 14.0 10.5 0.11 12.7 10.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Aminopep PF10023.9 PVD29150.1 - 0.055 12.8 1.4 0.078 12.3 1.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase TMF_DNA_bd PF12329.8 PVD29150.1 - 0.072 13.1 20.8 0.71 9.9 13.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 PVD29150.1 - 0.33 11.0 17.8 0.39 10.8 14.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 PVD29150.1 - 0.36 11.2 13.6 0.58 10.5 13.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TSC22 PF01166.18 PVD29150.1 - 0.67 10.3 7.4 4.1 7.8 1.1 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family GAS PF13851.6 PVD29150.1 - 0.97 8.7 18.0 4.8 6.5 18.0 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 PVD29150.1 - 0.98 9.2 17.3 1.4 8.7 4.8 2.7 2 1 1 3 3 3 0 Septum formation initiator Vfa1 PF08432.10 PVD29150.1 - 1.3 9.3 11.5 6.2 7.1 6.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Prefoldin_2 PF01920.20 PVD29150.1 - 3.1 7.8 21.6 0.4 10.7 6.9 2.9 2 1 0 3 3 3 0 Prefoldin subunit DUF2614 PF11023.8 PVD29150.1 - 6.2 6.9 7.0 13 5.9 0.9 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain ZapB PF06005.12 PVD29150.1 - 6.4 7.3 18.1 8.6 6.9 3.0 3.0 2 1 1 3 3 3 0 Cell division protein ZapB FlaC_arch PF05377.11 PVD29150.1 - 6.6 7.2 8.6 6 7.3 2.6 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_CLD PF14073.6 PVD29152.1 - 2.8e-48 164.3 18.0 2.8e-48 164.3 18.0 2.6 2 1 1 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 PVD29152.1 - 9.6e-15 54.8 2.1 9.6e-15 54.8 2.1 3.5 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Tsi6 PF18660.1 PVD29152.1 - 0.15 12.1 1.1 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 Tsi6 XhlA PF10779.9 PVD29152.1 - 8.1 6.7 18.4 7 6.9 0.7 4.4 4 0 0 4 4 4 0 Haemolysin XhlA tRNA-synt_1b PF00579.25 PVD29153.1 - 3.4e-39 134.9 0.0 4.7e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Telomere_Sde2_2 PF13297.6 PVD29153.1 - 0.00077 19.1 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal tRNA-synt_1b PF00579.25 PVD29154.1 - 8.8e-72 241.9 0.0 1.2e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 PVD29154.1 - 2.6e-29 101.2 0.0 6.9e-29 99.8 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain PhoH PF02562.16 PVD29154.1 - 0.12 11.8 0.0 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Acyltransf_C PF16076.5 PVD29155.1 - 8.8e-21 73.8 0.1 1.8e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 PVD29155.1 - 1.7e-15 56.8 0.0 3.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ABC_tran_CTD PF16326.5 PVD29156.1 - 0.022 15.0 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain zf-C2H2 PF00096.26 PVD29156.1 - 1.3 9.6 3.4 0.67 10.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type E2F_TDP PF02319.20 PVD29157.1 - 8.1e-39 131.5 0.6 9.7e-21 73.6 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 PVD29157.1 - 0.00051 19.9 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB CH PF00307.31 PVD29162.1 - 2e-06 27.9 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD29162.1 - 0.05 13.4 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 CAMSAP CH domain AAA PF00004.29 PVD29165.1 - 3.8e-07 30.6 0.1 1.4e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD29165.1 - 7.5e-07 29.5 0.3 5.9e-05 23.4 0.4 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD29165.1 - 6e-06 26.8 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PVD29165.1 - 1.8e-05 24.7 0.0 5.7e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PVD29165.1 - 2.4e-05 24.0 0.1 0.0033 17.0 0.0 3.0 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PVD29165.1 - 0.00015 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 PVD29165.1 - 0.00085 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 PVD29165.1 - 0.0015 18.7 0.0 0.0052 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD29165.1 - 0.0015 18.9 0.6 0.0039 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PVD29165.1 - 0.0017 18.8 1.5 0.012 16.1 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 PVD29165.1 - 0.003 17.3 0.0 0.0087 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PVD29165.1 - 0.0032 17.5 0.0 0.0078 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 PVD29165.1 - 0.0054 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 PVD29165.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 PVD29165.1 - 0.012 15.9 0.0 0.042 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD29165.1 - 0.024 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 PVD29165.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Torsin ResIII PF04851.15 PVD29165.1 - 0.059 13.4 0.0 0.9 9.5 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 PVD29165.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 PVD29165.1 - 0.098 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 PVD29165.1 - 0.11 12.3 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.14 PVD29165.1 - 0.13 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Lon_2 PF13337.6 PVD29165.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF2730 PF10805.8 PVD29165.1 - 0.22 11.6 7.8 0.23 11.6 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 PVD29165.1 - 0.73 10.3 8.8 0.14 12.6 2.6 2.6 3 0 0 3 3 2 0 Fez1 PRKG1_interact PF15898.5 PVD29165.1 - 1.3 9.9 10.4 10 7.1 3.3 3.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 PVD29165.1 - 1.5 7.6 6.2 3.9 6.3 2.6 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 PVD29165.1 - 8 7.2 12.5 0.68 10.6 1.7 3.2 4 0 0 4 4 2 0 Initiation control protein YabA EF-hand_1 PF00036.32 PVD29166.1 - 5.2e-11 41.3 19.4 2.8e-05 23.3 0.3 4.4 3 2 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD29166.1 - 5.3e-09 36.4 11.8 0.0015 18.9 1.1 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD29166.1 - 6.3e-09 35.1 14.5 0.0042 16.9 0.2 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PVD29166.1 - 3.4e-05 23.6 10.3 0.033 14.0 0.0 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD29166.1 - 5.3e-05 22.5 13.8 0.018 14.5 0.2 4.4 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 PVD29166.1 - 0.0015 18.4 0.9 1.2 9.2 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PVD29166.1 - 0.028 14.6 1.1 5.4 7.3 0.0 3.0 2 2 1 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 PVD29166.1 - 0.36 11.2 2.0 27 5.1 0.3 3.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region p450 PF00067.22 PVD29167.1 - 4.6e-39 134.4 0.0 8.3e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.32 PVD29167.1 - 8.8e-18 62.5 16.7 5.4e-05 22.5 0.1 7.5 7 3 1 8 8 8 5 EF hand EF-hand_7 PF13499.6 PVD29167.1 - 5.6e-14 52.4 15.3 3.5e-07 30.6 0.5 7.3 5 2 2 7 7 7 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD29167.1 - 3.8e-12 45.1 16.9 0.0047 16.8 0.1 8.3 7 1 1 8 8 8 4 EF-hand domain EF-hand_5 PF13202.6 PVD29167.1 - 2.5e-10 39.4 15.5 0.042 13.3 0.0 7.2 7 1 1 8 8 8 5 EF hand EF-hand_8 PF13833.6 PVD29167.1 - 8.6e-10 38.3 6.6 0.00023 21.0 0.1 5.5 4 1 1 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD29167.1 - 0.062 13.6 0.3 26 5.2 0.0 3.7 4 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Inhibitor_I34 PF10466.9 PVD29167.1 - 0.92 10.2 3.6 5 7.8 0.3 3.0 2 1 1 3 3 3 0 Saccharopepsin inhibitor I34 p450 PF00067.22 PVD29168.1 - 1.3e-38 133.0 0.0 1.5e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF229 PF02995.17 PVD29169.1 - 1.9e-112 376.4 0.0 2.9e-112 375.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD29169.1 - 0.001 18.5 0.2 0.0036 16.7 0.0 1.7 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 PVD29169.1 - 0.027 14.1 0.0 0.07 12.7 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD29169.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SCP2 PF02036.17 PVD29170.1 - 4e-19 69.0 0.1 7.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Band_7 PF01145.25 PVD29170.1 - 2.5e-17 63.4 0.1 4e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Alkyl_sulf_C PF14864.6 PVD29170.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DUF2076 PF09849.9 PVD29170.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ldl_recept_a PF00057.18 PVD29171.1 - 3.9e-14 52.6 36.1 2.3e-06 27.7 2.4 4.3 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD29171.1 - 5.6e-07 30.3 0.5 1.8e-06 28.6 0.5 1.9 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 PVD29172.1 - 1.3e-14 54.4 0.2 1.9e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 PVD29172.1 - 0.022 14.5 0.8 0.17 11.7 0.2 2.6 2 1 1 3 3 3 0 CUB-like domain GATase_6 PF13522.6 PVD29172.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Ldl_recept_a PF00057.18 PVD29173.1 - 1.5e-11 44.3 29.5 7.3e-07 29.3 0.9 3.2 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A p450 PF00067.22 PVD29174.1 - 6.9e-12 44.9 0.0 8.1e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metal_resist PF13801.6 PVD29174.1 - 0.2 11.9 0.4 0.26 11.5 0.4 1.1 1 0 0 1 1 1 0 Heavy-metal resistance CUB PF00431.20 PVD29175.1 - 1.9e-11 44.2 0.0 4.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 CUB domain Lectin_C PF00059.21 PVD29175.1 - 0.00098 19.8 0.0 0.0022 18.7 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain FGE-sulfatase PF03781.16 PVD29175.1 - 0.014 15.0 0.1 0.16 11.5 0.0 2.1 1 1 1 2 2 2 0 Sulfatase-modifying factor enzyme 1 Ldl_recept_a PF00057.18 PVD29175.1 - 0.094 13.0 2.5 0.3 11.4 2.5 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD29176.1 - 1e-16 61.2 0.0 6.5e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 PVD29176.1 - 4.7e-11 42.7 18.0 9.8e-08 32.1 0.5 3.9 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD29176.1 - 0.00039 21.1 0.1 0.00094 19.9 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Hemopexin PF00045.19 PVD29177.1 - 1.6e-14 53.6 0.8 6.9e-09 35.5 0.0 3.7 3 0 0 3 3 3 2 Hemopexin CUB PF00431.20 PVD29177.1 - 7.4e-13 48.8 0.0 8.3e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 CUB domain Lectin_C PF00059.21 PVD29177.1 - 0.00033 21.4 0.3 0.00084 20.1 0.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD29177.1 - 0.09 13.0 2.1 0.23 11.7 2.1 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Elf4 PF07011.11 PVD29177.1 - 0.49 10.3 1.9 0.72 9.8 0.5 2.0 2 0 0 2 2 2 0 Early Flowering 4 domain Hemopexin PF00045.19 PVD29178.1 - 1.1e-25 89.2 3.9 3.2e-08 33.4 0.0 6.8 6 0 0 6 6 6 5 Hemopexin CUB PF00431.20 PVD29178.1 - 4e-13 49.7 0.0 8.7e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 CUB domain Lectin_C PF00059.21 PVD29178.1 - 0.0018 19.0 0.0 0.0048 17.6 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD29178.1 - 0.043 14.0 1.2 0.12 12.6 1.2 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD29179.1 - 0.00036 21.2 0.0 0.0006 20.5 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD29179.1 - 0.0094 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like CUB PF00431.20 PVD29180.1 - 1.6e-11 44.5 0.0 7.6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 PVD29181.1 - 7.4e-12 45.3 17.8 4.8e-07 29.9 0.2 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Podoplanin PF05808.11 PVD29182.1 - 0.0011 19.0 0.3 0.0022 18.1 0.3 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 PVD29182.1 - 0.0064 15.9 4.2 0.011 15.1 4.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ADH_N PF08240.12 PVD29183.1 - 2e-27 95.2 0.1 3.8e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PVD29183.1 - 3.3e-23 82.1 0.4 2.2e-22 79.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD29183.1 - 9e-07 28.6 0.2 2.3e-06 27.2 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 PVD29183.1 - 0.00014 21.3 0.3 0.00022 20.6 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 PVD29183.1 - 0.0029 17.7 0.8 0.014 15.5 0.8 2.2 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SBP_bac_3 PF00497.20 PVD29183.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Pyr_redox_2 PF07992.14 PVD29183.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 PVD29183.1 - 0.11 13.6 0.0 0.19 12.8 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Mt_ATP-synt_B PF05405.14 PVD29184.1 - 3.8e-32 111.2 4.0 3.8e-32 111.2 4.0 1.7 3 0 0 3 3 3 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GerPC PF10737.9 PVD29184.1 - 0.34 10.9 8.0 0.7 9.9 8.0 1.4 1 0 0 1 1 1 0 Spore germination protein GerPC SH3_9 PF14604.6 PVD29185.1 - 3.2e-12 46.1 0.1 9e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PVD29185.1 - 3e-08 33.1 0.1 7.8e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 SH3 domain KAR9 PF08580.10 PVD29185.1 - 2.7 6.4 11.1 1.4 7.4 9.1 1.4 1 1 0 1 1 1 0 Yeast cortical protein KAR9 SAM_decarbox PF01536.16 PVD29186.1 - 2e-105 352.7 1.9 2.3e-105 352.5 1.3 1.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 PVD29187.1 - 1.3e-57 195.1 0.0 1.8e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29187.1 - 3.9e-21 75.5 0.1 8.4e-21 74.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PVD29187.1 - 0.0037 16.7 0.2 0.009 15.4 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD29187.1 - 0.0093 15.9 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family THAP PF05485.12 PVD29190.1 - 2.2e-13 50.9 1.8 2.2e-13 50.9 1.8 2.5 2 0 0 2 2 2 1 THAP domain VWC PF00093.18 PVD29192.1 - 1.1e-05 25.6 6.6 1.9e-05 24.9 6.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type C domain Amnionless PF14828.6 PVD29192.1 - 5.9e-05 22.1 3.6 5.9e-05 22.1 3.6 1.0 1 0 0 1 1 1 1 Amnionless EGF_CA PF07645.15 PVD29195.1 - 3e-18 65.7 21.9 1.3e-09 38.0 8.8 2.6 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 PVD29195.1 - 5.3e-08 32.9 22.7 0.00017 21.7 3.9 2.7 2 1 0 2 2 2 2 EGF domain EGF PF00008.27 PVD29195.1 - 0.0001 22.5 17.5 0.028 14.7 7.6 2.9 1 1 1 2 2 2 2 EGF-like domain hEGF PF12661.7 PVD29195.1 - 0.00055 20.5 12.1 0.0056 17.3 2.5 3.2 2 1 1 3 3 3 2 Human growth factor-like EGF Ig_6 PF18452.1 PVD29195.1 - 0.048 13.2 1.9 4.2 7.0 0.5 2.4 2 0 0 2 2 2 0 Immunoglobulin domain cEGF PF12662.7 PVD29195.1 - 0.057 13.4 3.4 0.057 13.4 3.4 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD29195.1 - 0.62 10.4 19.3 0.087 13.1 8.3 2.7 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site VWC PF00093.18 PVD29196.1 - 1.5e-11 44.4 32.2 5.4e-09 36.2 17.3 3.3 2 1 0 3 3 3 2 von Willebrand factor type C domain CFC PF09443.10 PVD29196.1 - 0.012 15.5 22.5 0.36 10.7 8.7 3.2 2 1 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) 7tm_1 PF00001.21 PVD29198.1 - 2.3e-15 56.6 13.6 3e-15 56.3 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD29199.1 - 1.7e-05 24.3 3.7 1.7e-05 24.3 3.7 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) PEMT PF04191.13 PVD29199.1 - 0.048 14.0 0.2 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Herpes_BMRF2 PF04633.12 PVD29199.1 - 0.13 11.5 7.2 0.59 9.3 7.2 1.8 1 1 0 1 1 1 0 Herpesvirus BMRF2 protein SHIPPO-rpt PF07004.12 PVD29200.1 - 6.6e-15 55.2 27.6 0.0002 22.1 0.0 6.2 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 PVD29201.1 - 9.4e-17 61.1 29.4 0.00056 20.7 3.9 6.4 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat Luciferase_N PF05295.11 PVD29203.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain APG5 PF04106.12 PVD29204.1 - 6.9e-60 202.5 1.3 9.9e-60 201.9 1.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Snf7 PF03357.21 PVD29206.1 - 7.5e-45 152.6 29.8 7.5e-45 152.6 29.8 1.4 1 1 1 2 2 2 1 Snf7 FapA PF03961.13 PVD29206.1 - 1.2 7.7 12.1 1.4 7.4 12.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2570 PF10828.8 PVD29206.1 - 1.8 8.4 19.6 1.1 9.1 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF3349 PF11829.8 PVD29206.1 - 4.7 8.1 8.4 0.54 11.1 1.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) CSD PF00313.22 PVD29207.1 - 2.7e-70 232.2 16.7 8e-15 54.4 0.0 9.3 9 0 0 9 9 9 8 'Cold-shock' DNA-binding domain S1-like PF14444.6 PVD29207.1 - 6.2e-14 51.7 5.7 0.0085 16.0 0.0 6.8 7 0 0 7 7 7 4 S1-like CusF_Ec PF11604.8 PVD29207.1 - 5e-08 32.8 4.2 3.9 7.5 0.0 7.8 9 0 0 9 9 9 2 Copper binding periplasmic protein CusF SUZ-C PF12901.7 PVD29207.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 SUZ-C motif MazE_antitoxin PF04014.18 PVD29207.1 - 0.021 14.8 0.5 14 5.7 0.0 4.4 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF2196 PF09962.9 PVD29207.1 - 0.027 14.4 1.9 0.87 9.6 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2196) RsgA_N PF16745.5 PVD29207.1 - 0.035 13.9 6.9 40 4.1 0.0 6.5 8 0 0 8 8 8 0 RsgA N-terminal domain Cyclophil_like2 PF18050.1 PVD29207.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Cyclophilin-like family Methyltransf_25 PF13649.6 PVD29209.1 - 6.5e-13 49.2 0.2 2.2e-12 47.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD29209.1 - 1.6e-10 41.5 0.1 4.9e-10 39.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 PVD29209.1 - 8.3e-10 38.5 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PVD29209.1 - 8.3e-10 38.6 0.1 2e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD29209.1 - 2.3e-07 30.1 0.1 3.6e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 PVD29209.1 - 4.2e-07 29.7 0.0 8.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PVD29209.1 - 3.4e-05 23.7 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD29209.1 - 0.00011 22.8 0.1 0.00044 20.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD29209.1 - 0.00046 19.6 0.1 0.00077 18.9 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 PVD29209.1 - 0.001 19.1 1.2 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PVD29209.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PVD29209.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 PVD29209.1 - 0.0051 17.8 0.1 0.042 14.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 PVD29209.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 PVD29209.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5_C PF17286.2 PVD29209.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PCMT PF01135.19 PVD29209.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) C2 PF00168.30 PVD29210.1 - 1.2e-39 134.8 0.1 2.4e-20 72.7 0.1 2.3 2 0 0 2 2 2 2 C2 domain Orexin PF02072.15 PVD29212.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Prepro-orexin FYVE_2 PF02318.16 PVD29214.1 - 4.1e-19 69.0 5.1 5.4e-19 68.6 5.1 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 PVD29214.1 - 0.018 15.2 4.4 0.033 14.4 4.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ribosomal_L29 PF00831.23 PVD29214.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal L29 protein FliT PF05400.13 PVD29214.1 - 0.059 14.2 1.1 0.14 12.9 1.0 1.7 2 0 0 2 2 2 0 Flagellar protein FliT Macoilin PF09726.9 PVD29214.1 - 0.14 10.7 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Macoilin family DZR PF12773.7 PVD29214.1 - 0.24 11.4 5.8 38 4.4 5.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 PVD29214.1 - 0.51 10.5 8.6 0.92 9.7 8.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 PVD29214.1 - 1.5 8.7 13.0 4 7.4 13.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OSCP PF00213.18 PVD29215.1 - 2.8e-46 157.8 0.1 3.6e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit MIP PF00230.20 PVD29216.1 - 4.2e-46 157.5 5.4 5.1e-46 157.2 5.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L19 PF01245.20 PVD29218.1 - 3.1e-15 56.1 0.1 6.7e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 HrpB7 PF09486.10 PVD29218.1 - 0.009 16.4 1.6 0.009 16.4 1.6 1.8 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 PVD29219.1 - 1.6e-24 86.7 0.4 7.5e-12 45.2 0.9 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29219.1 - 5.7e-11 42.2 0.8 0.00027 20.3 0.9 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD29219.1 - 0.00012 21.5 0.1 0.0052 16.1 0.1 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD29219.1 - 0.0048 15.7 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD29219.1 - 0.03 13.3 0.1 0.062 12.2 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PVD29219.1 - 0.1 12.5 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD29219.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 PVD29220.1 - 0.096 13.6 0.1 0.4 11.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3328 PF11807.8 PVD29220.1 - 0.66 9.7 2.1 0.55 10.0 0.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3328) TMEM154 PF15102.6 PVD29220.1 - 1.5 8.7 5.7 3.1 7.7 5.3 1.8 1 1 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 PVD29220.1 - 6.3 7.0 10.9 0.12 12.6 3.0 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Chromo PF00385.24 PVD29221.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2_4 PF13894.6 PVD29222.1 - 0.015 16.1 0.8 0.015 16.1 0.8 6.2 4 1 1 5 5 5 0 C2H2-type zinc finger Macoilin PF09726.9 PVD29222.1 - 5 5.6 17.7 6.4 5.2 17.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF3087 PF11286.8 PVD29223.1 - 5.9 6.3 6.8 0.59 9.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) LicD PF04991.13 PVD29224.1 - 3.7e-16 60.0 8.1 1.3e-12 48.3 1.9 2.9 2 1 0 3 3 3 2 LicD family DUF3958 PF13125.6 PVD29224.1 - 0.058 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Methyltransf_4 PF02390.17 PVD29224.1 - 0.15 11.5 0.2 0.33 10.4 0.2 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF872 PF05915.12 PVD29225.1 - 2.4e-30 105.1 0.0 2.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DsbD PF02683.15 PVD29225.1 - 0.0025 17.8 0.4 0.0031 17.4 0.4 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF3040 PF11239.8 PVD29225.1 - 0.0061 16.8 0.9 0.013 15.7 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Cation_ATPase_C PF00689.21 PVD29225.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.9 PVD29225.1 - 0.079 11.7 0.0 0.085 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.6 PVD29225.1 - 0.17 12.0 3.5 0.3 11.2 3.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF5381 PF17353.2 PVD29225.1 - 0.23 11.2 1.1 0.35 10.6 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DUF2065 PF09838.9 PVD29225.1 - 1.9 8.5 7.9 0.13 12.3 1.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) E1_dh PF00676.20 PVD29226.1 - 1.5e-164 546.2 3.5 3.8e-81 272.3 0.0 3.1 2 1 0 2 2 2 2 Dehydrogenase E1 component PfkB PF00294.24 PVD29226.1 - 9.3e-23 81.0 0.0 2.1e-13 50.3 0.1 2.3 1 1 1 2 2 2 2 pfkB family carbohydrate kinase DXP_synthase_N PF13292.6 PVD29226.1 - 8.6e-11 41.5 1.4 0.00024 20.4 0.1 2.4 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 PVD29226.1 - 4e-07 29.9 7.1 0.002 18.0 0.9 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1186 PF06685.11 PVD29226.1 - 0.036 13.4 1.3 5.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) IR1-M PF12185.8 PVD29226.1 - 0.041 13.8 0.1 9.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain BCL9 PF11502.8 PVD29226.1 - 1.6 8.6 3.3 4.3 7.2 3.3 1.7 1 0 0 1 1 1 0 B-cell lymphoma 9 protein E1_dh PF00676.20 PVD29227.1 - 1.7e-105 352.2 2.1 4.9e-104 347.5 0.0 2.0 1 1 0 2 2 2 2 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PVD29227.1 - 0.00054 19.2 0.1 0.00099 18.4 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 PVD29227.1 - 0.0013 18.5 0.6 0.0025 17.6 0.6 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2717 PF10911.8 PVD29227.1 - 0.053 13.2 0.0 7.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2717) TPR_14 PF13428.6 PVD29229.1 - 5.1e-12 45.6 0.1 0.0091 16.7 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD29229.1 - 1.5e-11 43.5 0.9 0.00013 21.8 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD29229.1 - 6e-11 41.8 1.2 3.3e-06 26.7 0.1 3.6 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.6 PVD29229.1 - 1.2e-10 41.7 1.4 7.1e-05 23.2 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD29229.1 - 2.3e-10 39.8 0.1 0.006 16.7 0.0 4.8 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD29229.1 - 7e-10 39.1 2.9 0.0013 19.0 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD29229.1 - 3.1e-09 36.3 3.8 0.00021 21.0 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD29229.1 - 2.8e-08 33.9 0.2 0.021 15.1 0.0 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PVD29229.1 - 1.3e-07 31.5 1.9 0.8 10.2 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD29229.1 - 3.5e-07 29.8 2.8 0.082 13.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD29229.1 - 1e-06 29.0 0.1 0.22 12.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD29229.1 - 1.6e-05 25.4 0.4 0.073 13.7 0.2 3.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 PVD29229.1 - 3.8e-05 23.9 1.3 3 8.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD29229.1 - 0.00021 20.6 0.3 0.0065 15.7 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD29229.1 - 0.00033 20.4 5.3 0.2 11.6 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 PVD29229.1 - 0.0019 17.2 0.2 0.92 8.3 0.0 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 PVD29229.1 - 0.0072 16.0 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 PVD29229.1 - 0.0079 16.3 0.4 4 7.7 0.0 3.0 2 1 2 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD29229.1 - 0.022 14.2 0.1 0.049 13.0 0.0 1.5 1 1 1 2 2 2 0 Coatomer epsilon subunit Type_III_YscG PF09477.10 PVD29229.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) SRP_TPR_like PF17004.5 PVD29229.1 - 0.094 12.7 0.1 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Putative TPR-like repeat Ank_5 PF13857.6 PVD29230.1 - 0.00011 22.4 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD29230.1 - 0.00014 22.4 0.1 0.0003 21.3 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29230.1 - 0.00056 20.4 0.1 0.053 14.1 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ribosomal_L1 PF00687.21 PVD29231.1 - 1.4e-42 145.7 3.6 1.7e-42 145.5 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 PVD29231.1 - 0.0027 17.8 1.5 0.0056 16.7 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function TIG_plexin PF17960.1 PVD29231.1 - 0.1 12.6 0.2 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 TIG domain UCH PF00443.29 PVD29232.1 - 2.3e-38 132.1 1.6 4.4e-38 131.2 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD29232.1 - 3.9e-27 95.7 1.7 1.5e-26 93.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.11 PVD29232.1 - 0.12 12.4 3.7 0.46 10.5 3.7 2.0 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD29232.1 - 0.92 9.6 12.4 2.1 8.4 12.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PVD29232.1 - 9.1 5.7 9.8 22 4.4 9.8 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SASRP1 PF15160.6 PVD29233.1 - 6.3e-14 52.2 1.2 8.3e-10 38.7 0.1 2.1 1 1 1 2 2 2 2 Spermatogenesis-associated serine-rich protein 1 MFS_1 PF07690.16 PVD29234.1 - 1.5e-19 70.1 28.5 1.7e-17 63.4 29.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD29234.1 - 6.9e-11 41.7 22.6 3.8e-10 39.2 22.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 PVD29235.1 - 1.7e-21 76.6 23.7 2.5e-21 76.1 23.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD29235.1 - 2e-17 63.2 67.4 6.1e-15 55.0 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.11 PVD29235.1 - 0.045 13.5 2.7 0.17 11.6 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Sugar_tr PF00083.24 PVD29236.1 - 6.4e-37 127.5 20.3 2.7e-18 66.1 3.4 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 PVD29236.1 - 2.4e-19 69.5 35.2 9.5e-11 41.2 5.4 3.6 4 0 0 4 4 4 3 Major Facilitator Superfamily DUF1440 PF07274.12 PVD29236.1 - 0.0011 19.3 3.2 0.77 10.1 0.3 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1440) PRRSV_2b PF07069.11 PVD29236.1 - 0.0013 19.2 5.7 9.4 6.8 0.1 4.2 3 0 0 3 3 3 2 Porcine reproductive and respiratory syndrome virus 2b AmiS_UreI PF02293.15 PVD29236.1 - 0.0013 18.7 16.7 0.27 11.2 0.1 3.8 4 0 0 4 4 4 3 AmiS/UreI family transporter PMP1_2 PF08114.11 PVD29236.1 - 0.0041 16.8 11.0 2.7 7.8 1.0 4.1 4 0 0 4 4 4 3 ATPase proteolipid family TPR_10 PF13374.6 PVD29236.1 - 0.05 13.5 0.2 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2905 PF11146.8 PVD29236.1 - 0.57 10.4 12.8 0.69 10.1 0.7 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2905) Sugar_tr PF00083.24 PVD29237.1 - 5e-18 65.2 12.5 8.2e-18 64.5 12.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD29237.1 - 2e-09 36.8 20.5 3.7e-09 36.0 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UK PF02512.14 PVD29237.1 - 0.025 15.1 0.3 35 5.0 0.0 3.7 3 0 0 3 3 3 0 Virulence determinant AviRa PF11599.8 PVD29237.1 - 0.043 13.3 2.1 13 5.1 0.1 3.2 3 0 0 3 3 3 0 RRNA methyltransferase AviRa FAM72 PF14976.6 PVD29237.1 - 2.6 8.2 9.5 3.7 7.7 0.8 3.0 3 0 0 3 3 3 0 FAM72 protein Zwint PF15556.6 PVD29238.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ZW10 interactor 7tm_1 PF00001.21 PVD29240.1 - 1.9e-15 56.9 2.3 1e-14 54.5 0.2 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29240.1 - 0.00025 20.5 5.5 0.043 13.2 1.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zn-ribbon_14 PF16503.5 PVD29242.1 - 1.9e-18 65.7 2.3 1.9e-18 65.7 2.3 2.0 2 0 0 2 2 2 1 Zinc-ribbon ATP_bind_3 PF01171.20 PVD29242.1 - 7e-08 32.4 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 PVD29242.1 - 0.025 14.1 2.1 0.025 14.1 2.1 3.0 3 0 0 3 3 3 0 RecR protein CTU2 PF10288.9 PVD29242.1 - 0.1 12.9 3.2 0.47 10.7 3.1 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 HLH PF00010.26 PVD29243.1 - 3.9e-13 49.1 0.6 9.9e-13 47.8 0.3 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain CC PF04942.14 PVD29244.1 - 0.94 9.7 13.3 1.1e+02 3.1 0.3 6.1 2 2 4 7 7 7 0 CC domain Exo_endo_phos PF03372.23 PVD29244.1 - 6.5 6.2 5.4 4.6e+02 0.1 5.4 3.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Insulin PF00049.18 PVD29245.1 - 0.0018 19.3 3.1 0.0033 18.4 3.1 1.6 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family CHORD PF04968.12 PVD29247.1 - 9.8e-46 154.3 14.7 3.5e-25 88.5 7.8 2.7 2 0 0 2 2 2 2 CHORD Methyltransf_22 PF13383.6 PVD29247.1 - 1.2e-15 57.8 0.8 5.5e-15 55.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain CS PF04969.16 PVD29247.1 - 4.8e-09 37.1 0.1 9.2e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 CS domain BTK PF00779.19 PVD29247.1 - 3.9 7.4 13.8 2.1 8.2 0.5 3.4 3 1 0 3 3 3 0 BTK motif DHC_N1 PF08385.12 PVD29248.1 - 1.2e-92 311.4 6.5 3.9e-79 266.8 1.0 6.0 6 2 0 6 6 5 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PVD29248.1 - 1.5e-88 297.6 7.3 1.5e-88 297.6 7.3 6.3 7 1 0 7 7 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PVD29248.1 - 4.8e-63 213.1 0.0 3.6e-47 160.9 0.0 3.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 PVD29248.1 - 1.1e-44 153.0 0.0 4.2e-44 151.0 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD29248.1 - 9e-44 149.7 0.5 1.9e-42 145.4 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD29248.1 - 5.9e-42 143.2 0.9 5.1e-37 127.1 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_9 PF12781.7 PVD29248.1 - 7.3e-27 93.9 1.7 7.3e-27 93.9 1.7 2.9 2 0 0 2 2 1 1 ATP-binding dynein motor region Sec63 PF02889.16 PVD29248.1 - 3.4e-18 65.7 3.0 3.3e-10 39.6 0.6 2.7 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 PVD29248.1 - 2.7e-16 59.4 0.3 8.9e-16 57.8 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain Dynein_AAA_lid PF17852.1 PVD29248.1 - 3.2e-16 59.6 1.1 2.8e-14 53.3 0.0 4.1 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PVD29248.1 - 2.9e-11 43.9 0.1 0.0091 16.4 0.0 4.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_11 PF18198.1 PVD29248.1 - 7.3e-11 42.2 0.1 5.1e-10 39.4 0.0 2.6 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD29248.1 - 8.9e-09 35.5 0.0 0.028 14.4 0.0 4.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD29248.1 - 2.5e-07 31.2 12.4 0.0011 19.3 0.0 6.5 7 0 0 7 7 5 2 AAA ATPase domain AAA_18 PF13238.6 PVD29248.1 - 3e-07 31.1 0.9 0.043 14.4 0.0 5.3 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 PVD29248.1 - 5.6e-07 29.9 4.4 0.29 11.4 0.0 5.2 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 PVD29248.1 - 1e-05 25.5 0.2 0.18 11.7 0.0 3.1 2 0 0 2 2 2 2 RsgA GTPase AAA_lid_1 PF17857.1 PVD29248.1 - 1e-05 25.6 0.1 9.2e-05 22.6 0.1 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 PVD29248.1 - 1.6e-05 24.5 5.6 0.016 14.9 0.0 3.9 5 0 0 5 5 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 PVD29248.1 - 8e-05 22.4 0.7 2.8 7.6 0.0 3.8 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 PVD29248.1 - 8.5e-05 21.8 0.5 0.093 11.9 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) TsaE PF02367.17 PVD29248.1 - 0.00012 22.0 0.6 1.2 9.2 0.0 3.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PVD29248.1 - 0.00032 21.0 0.6 9.9 6.5 0.0 4.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PVD29248.1 - 0.00035 20.9 1.2 1.6 9.1 0.0 4.7 4 0 0 4 4 4 1 RNA helicase Mg_chelatase PF01078.21 PVD29248.1 - 0.00061 19.2 1.2 0.047 13.1 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PVD29248.1 - 0.002 18.2 1.3 0.055 13.5 0.0 4.0 5 0 0 5 5 5 1 AAA domain Sigma54_activat PF00158.26 PVD29248.1 - 0.0027 17.4 0.8 0.28 10.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 PVD29248.1 - 0.0038 17.0 0.0 7.3 6.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 PVD29248.1 - 0.0083 16.3 1.1 6 7.0 0.0 4.5 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 PVD29248.1 - 0.012 16.1 0.0 0.012 16.1 0.0 4.9 5 0 0 5 5 3 0 ABC transporter Septin PF00735.18 PVD29248.1 - 0.02 14.2 7.1 0.2 10.9 0.1 2.9 3 0 0 3 3 2 0 Septin AIG1 PF04548.16 PVD29248.1 - 0.022 14.1 0.5 5.9 6.2 0.0 3.1 2 0 0 2 2 2 0 AIG1 family FtsK_SpoIIIE PF01580.18 PVD29248.1 - 0.024 14.0 2.4 1.3 8.4 0.1 3.0 3 0 0 3 3 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 PVD29248.1 - 0.025 14.5 9.7 1 9.2 0.1 4.3 4 0 0 4 4 3 0 NTPase Rad17 PF03215.15 PVD29248.1 - 0.038 13.9 0.7 14 5.5 0.1 3.9 3 0 0 3 3 3 0 Rad17 P-loop domain T2SSE PF00437.20 PVD29248.1 - 0.077 12.1 0.1 3.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 PVD29248.1 - 0.087 12.5 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 PVD29248.1 - 0.3 11.0 4.6 1.4 8.8 0.0 4.0 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 PVD29248.1 - 0.87 9.1 4.1 1.8 8.1 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PVD29248.1 - 1.7 8.5 7.7 8.8 6.2 0.0 4.5 5 0 0 5 5 4 0 NACHT domain NOT2_3_5 PF04153.18 PVD29249.1 - 5.9e-34 117.0 0.6 1.1e-33 116.1 0.6 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family PCI PF01399.27 PVD29250.1 - 1.7e-10 41.3 0.0 4.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain DUF5344 PF17279.2 PVD29250.1 - 0.037 14.6 0.1 0.37 11.4 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF4298 PF14131.6 PVD29250.1 - 1.3 9.1 5.0 7.9 6.5 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) UCH PF00443.29 PVD29251.1 - 1.8e-47 162.0 0.0 3.5e-47 161.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PVD29251.1 - 3.3e-18 65.8 3.0 3.3e-18 65.8 3.0 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_9 PF14369.6 PVD29251.1 - 0.097 12.9 2.9 0.29 11.4 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon RRM_1 PF00076.22 PVD29252.1 - 7.5e-14 51.3 0.0 1.1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD29252.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RcpC PF16976.5 PVD29253.1 - 0.033 14.2 1.0 0.12 12.5 0.2 2.1 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Ank_2 PF12796.7 PVD29254.1 - 1.4e-96 317.2 24.0 3.6e-17 62.7 2.4 8.7 3 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29254.1 - 8.2e-91 297.3 28.8 1.3e-12 47.9 0.0 11.4 7 3 6 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29254.1 - 1.3e-83 273.9 30.3 3.1e-11 43.3 0.7 13.0 3 1 11 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29254.1 - 1.2e-78 249.6 27.7 1.2e-05 25.2 0.0 17.3 18 0 0 18 18 18 13 Ankyrin repeat Ank PF00023.30 PVD29254.1 - 4.3e-75 245.1 35.0 4.9e-07 29.9 0.2 15.9 16 1 0 16 16 16 13 Ankyrin repeat Ion_trans PF00520.31 PVD29254.1 - 3.3e-09 36.4 0.0 4.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Sacchrp_dh_NADP PF03435.18 PVD29254.1 - 0.1 12.9 0.6 4.6 7.5 0.0 3.4 2 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain GATase_7 PF13537.6 PVD29254.1 - 0.11 12.3 0.0 34 4.4 0.0 3.8 4 0 0 4 4 4 0 Glutamine amidotransferase domain WBP-1 PF11669.8 PVD29255.1 - 0.15 12.8 2.1 0.25 12.0 1.3 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 ABC_tran PF00005.27 PVD29256.1 - 1.3e-29 103.4 0.0 2.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD29256.1 - 0.00021 20.8 0.1 0.0014 18.1 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 PVD29256.1 - 0.054 12.8 0.3 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 PVD29256.1 - 0.074 13.1 0.3 0.28 11.3 0.2 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 PVD29256.1 - 0.21 11.3 1.0 9.5 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 PVD29256.1 - 0.29 11.2 1.1 0.59 10.2 1.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 PVD29256.1 - 1.2 8.8 4.2 7.9 6.1 0.2 2.9 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 PVD29257.1 - 3.6e-28 98.5 52.9 9e-22 77.5 34.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD29257.1 - 8.9e-27 94.0 20.0 1.5e-26 93.3 20.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2070 PF09843.9 PVD29257.1 - 4.5 5.4 23.8 1.4 7.1 9.9 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2070) HSP20 PF00011.21 PVD29258.1 - 3.3e-21 75.3 0.0 4.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD29258.1 - 0.0007 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA RRM_1 PF00076.22 PVD29259.1 - 3.1e-54 180.7 0.8 1.5e-16 59.9 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PVD29259.1 - 6.6e-07 29.3 0.0 0.62 10.1 0.0 3.8 3 0 0 3 3 3 2 RNA binding domain RRM_7 PF16367.5 PVD29259.1 - 1.8e-05 24.8 0.0 0.072 13.2 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 PVD29259.1 - 0.0022 18.2 3.0 7.7 6.7 0.3 4.2 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 PVD29259.1 - 0.0056 16.7 0.1 6.9 6.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 PVD29259.1 - 0.24 11.6 3.3 2.9 8.2 0.0 3.3 4 0 0 4 4 4 0 BRCA1-associated protein 2 PepSY_2 PF13670.6 PVD29260.1 - 0.23 11.5 3.6 0.32 11.0 3.6 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RRM_1 PF00076.22 PVD29261.1 - 2.6e-15 56.0 0.0 6e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD29261.1 - 0.00035 20.6 0.0 0.00082 19.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif EF-hand_1 PF00036.32 PVD29261.1 - 0.18 11.5 2.0 8.7 6.2 0.1 3.3 3 0 0 3 3 3 0 EF hand Med19 PF10278.9 PVD29261.1 - 7.8 6.4 15.4 11 5.8 5.4 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Sugar_tr PF00083.24 PVD29262.1 - 6.6e-05 22.0 0.0 0.00014 20.9 0.0 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter SID-1_RNA_chan PF13965.6 PVD29266.1 - 6.2 5.1 16.9 1.3e+02 0.7 16.9 2.1 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4148 PF13663.6 PVD29267.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) SpoIIIAH PF12685.7 PVD29267.1 - 0.2 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Pro-rich PF15240.6 PVD29268.1 - 7.4e-06 26.4 5.4 8.9e-06 26.1 5.4 1.0 1 0 0 1 1 1 1 Proline-rich GRP PF07172.11 PVD29268.1 - 4.6 8.0 16.1 51 4.6 16.1 2.1 1 1 0 1 1 1 0 Glycine rich protein family DUF4148 PF13663.6 PVD29269.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) BNR_6 PF15899.5 PVD29270.1 - 0.026 14.5 6.6 84 3.7 0.1 4.3 4 0 0 4 4 4 0 BNR-Asp box repeat KCNQ_channel PF03520.14 PVD29271.1 - 1.9e-27 96.3 4.9 7.1e-27 94.5 4.8 1.9 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 PVD29271.1 - 1.1e-25 90.3 15.8 1.6e-25 89.8 15.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD29271.1 - 2.3e-12 46.7 8.5 2.3e-12 46.7 8.5 2.5 2 0 0 2 2 2 1 Ion channel 7tm_7 PF08395.12 PVD29271.1 - 1.6 7.8 13.7 2.3 7.3 0.3 2.7 1 1 0 2 2 2 0 7tm Chemosensory receptor Lig_chan PF00060.26 PVD29271.1 - 2 8.3 5.1 0.23 11.3 0.2 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel CD225 PF04505.12 PVD29271.1 - 6.7 6.9 6.9 1 9.6 0.1 2.8 3 0 0 3 3 3 0 Interferon-induced transmembrane protein adh_short_C2 PF13561.6 PVD29272.1 - 2.4e-43 148.4 0.3 3.7e-43 147.7 0.3 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD29272.1 - 1.3e-41 142.3 0.3 1.6e-41 141.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 PVD29272.1 - 9.2e-06 25.7 0.4 1.7e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 PVD29272.1 - 3.4e-05 23.8 0.1 4.4e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 PVD29272.1 - 0.00026 20.9 0.3 0.00044 20.2 0.3 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 PVD29272.1 - 0.012 15.0 0.5 0.016 14.5 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2099 PF09872.9 PVD29272.1 - 0.091 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Phos_pyr_kin PF08543.12 PVD29273.1 - 1.5e-20 73.6 0.0 2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 PVD29273.1 - 4.2e-14 52.6 0.1 8.6e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase KCNQ_channel PF03520.14 PVD29274.1 - 2.8e-25 89.3 0.5 5.4e-25 88.3 0.5 1.5 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 PVD29274.1 - 1.3e-24 86.8 14.2 2e-24 86.2 14.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD29274.1 - 3.1e-12 46.3 4.5 3.1e-12 46.3 4.5 2.7 3 0 0 3 3 3 1 Ion channel DUF2798 PF11391.8 PVD29274.1 - 0.015 15.3 1.1 0.015 15.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) GCR1_C PF12550.8 PVD29274.1 - 0.072 13.4 0.4 1 9.7 0.0 2.5 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes Sensor PF13796.6 PVD29274.1 - 0.13 12.3 0.0 0.13 12.3 0.0 2.3 2 1 0 2 2 2 0 Putative sensor Lig_chan PF00060.26 PVD29274.1 - 1.2 8.9 5.7 0.16 11.8 0.3 2.2 2 1 0 2 2 2 0 Ligand-gated ion channel IQ PF00612.27 PVD29274.1 - 5.7 7.0 6.7 0.57 10.1 0.8 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif CD225 PF04505.12 PVD29274.1 - 6.1 7.1 7.7 1.5 9.0 0.1 3.6 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Lectin_C PF00059.21 PVD29277.1 - 2e-16 60.7 2.6 2.5e-16 60.3 2.6 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD29277.1 - 0.031 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like p450 PF00067.22 PVD29278.1 - 7.7e-43 146.9 0.1 9.9e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Oscp1 PF10188.9 PVD29279.1 - 9.7e-76 253.8 11.8 1.5e-75 253.1 11.8 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 Methyltr_RsmB-F PF01189.17 PVD29280.1 - 2.4e-28 99.1 0.0 3.1e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PVD29280.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 PVD29281.1 - 7.9e-18 64.5 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PVD29281.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B GTSE1_N PF15259.6 PVD29281.1 - 0.09 13.0 0.6 0.18 12.0 0.6 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 RWD PF05773.22 PVD29281.1 - 0.18 12.1 0.1 0.4 11.0 0.0 1.6 2 0 0 2 2 2 0 RWD domain Pkinase PF00069.25 PVD29282.1 - 4e-67 226.4 0.0 7.3e-67 225.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29282.1 - 1e-41 143.0 0.0 1.6e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD29282.1 - 5.1e-09 35.9 0.0 1.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD29282.1 - 0.0013 17.6 0.9 0.0022 16.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase T3SS_basalb_I PF17001.5 PVD29282.1 - 0.54 10.9 4.8 0.38 11.4 0.2 2.9 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI 7TM_GPCR_Srh PF10318.9 PVD29283.1 - 0.0016 17.6 0.3 0.0023 17.0 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Y_phosphatase PF00102.27 PVD29284.1 - 8.7e-23 81.1 0.6 6.5e-12 45.5 0.0 2.6 1 1 1 2 2 2 2 Protein-tyrosine phosphatase IL2RB_N1 PF18707.1 PVD29286.1 - 1.3 9.6 19.3 9.6 6.8 7.1 3.9 3 1 0 3 3 3 0 Interleukin-2 receptor subunit beta N-terminal domain 1 fn3 PF00041.21 PVD29287.1 - 2.7e-06 27.6 3.1 0.065 13.6 0.1 4.8 5 0 0 5 5 5 3 Fibronectin type III domain IL3Ra_N PF18611.1 PVD29287.1 - 1.2 9.1 7.0 0.19 11.7 1.6 2.5 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain Y_phosphatase PF00102.27 PVD29288.1 - 1.4e-53 181.9 1.5 2.7e-47 161.3 0.0 2.9 2 1 1 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.21 PVD29288.1 - 2.7e-06 27.6 3.9 0.91 9.9 0.5 5.8 5 1 1 6 6 6 3 Fibronectin type III domain PLDc_N PF13396.6 PVD29288.1 - 0.03 14.3 0.5 0.054 13.4 0.5 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal IL3Ra_N PF18611.1 PVD29288.1 - 0.24 11.4 5.2 0.082 12.9 1.7 2.1 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain 7tm_1 PF00001.21 PVD29289.1 - 3.5e-53 180.6 19.6 5.8e-53 179.9 19.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29289.1 - 7.9e-09 35.3 14.1 1.5e-08 34.3 14.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD29289.1 - 7.6e-08 32.4 13.4 3.1e-07 30.4 13.4 2.1 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD29289.1 - 0.034 13.8 24.8 0.032 13.9 20.6 2.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Pox_A9 PF04835.12 PVD29289.1 - 0.99 9.6 4.6 0.24 11.5 0.6 2.1 2 0 0 2 2 2 0 A9 protein conserved region p450 PF00067.22 PVD29290.1 - 1.1e-55 189.2 0.1 7.3e-37 127.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 7tm_1 PF00001.21 PVD29292.1 - 0.019 14.3 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD29293.1 - 6e-07 29.1 0.1 6.8e-07 28.9 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD29294.1 - 4.2e-08 32.8 1.3 4.2e-08 32.8 1.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) TTL PF03133.15 PVD29295.1 - 2.6e-50 171.2 0.0 9.1e-46 156.3 0.0 2.5 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family DEAD PF00270.29 PVD29295.1 - 9.9e-50 168.7 1.5 1.4e-49 168.2 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD29295.1 - 9.7e-24 83.9 0.0 1.6e-22 80.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PVD29295.1 - 2.9e-12 46.6 2.0 6.9e-12 45.4 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) STI1 PF17830.1 PVD29295.1 - 5.5e-06 26.2 0.3 2.7e-05 24.0 0.2 2.2 1 1 1 2 2 2 2 STI1 domain AAA_30 PF13604.6 PVD29295.1 - 0.0063 16.2 0.0 0.14 11.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 PVD29295.1 - 0.1 11.9 4.9 0.047 13.0 1.9 1.9 2 1 0 2 2 2 0 SecA DEAD-like domain SET PF00856.28 PVD29295.1 - 1.4 9.3 3.4 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 SET domain C2 PF00168.30 PVD29296.1 - 7.2e-51 170.8 0.1 7e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 C2 domain CD34_antigen PF06365.12 PVD29297.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family PRIMA1 PF16101.5 PVD29297.1 - 0.25 11.4 1.2 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Potassium_chann PF11404.8 PVD29297.1 - 0.39 10.6 0.2 0.39 10.6 0.2 2.2 2 0 0 2 2 2 0 Potassium voltage-gated channel Glycoprotein_G PF00802.19 PVD29301.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.3 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G PT PF04886.12 PVD29301.1 - 0.096 12.2 0.4 0.37 10.4 0.4 2.0 1 0 0 1 1 1 0 PT repeat 7tm_1 PF00001.21 PVD29303.1 - 2.6e-39 135.2 17.2 3.9e-39 134.6 17.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD29303.1 - 0.051 13.2 15.9 0.013 15.2 6.9 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx uDENN PF03456.18 PVD29304.1 - 0.038 14.7 1.2 0.038 14.7 1.2 4.0 4 0 0 4 4 4 0 uDENN domain Kazal_1 PF00050.21 PVD29304.1 - 1.7 8.7 39.6 1.8 8.6 1.2 6.7 6 1 1 7 7 7 0 Kazal-type serine protease inhibitor domain RL10P_insert PF17777.1 PVD29305.1 - 0.022 14.8 0.1 4.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P Kazal_1 PF00050.21 PVD29305.1 - 8.7 6.4 10.0 2.5 8.2 2.2 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF5572 PF17733.1 PVD29306.1 - 0.82 9.6 5.0 36 4.3 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5572) SKG6 PF08693.10 PVD29307.1 - 6.8e-06 25.4 0.3 1.3e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DHC_N2 PF08393.13 PVD29308.1 - 3.6e-118 395.2 5.9 3.6e-118 395.2 5.9 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PVD29308.1 - 9.1e-105 350.2 0.0 3.3e-68 230.1 0.0 2.6 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 PVD29308.1 - 3.6e-98 328.6 0.0 3.6e-98 328.6 0.0 2.7 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD29308.1 - 1.9e-80 270.0 0.0 7.3e-80 268.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 PVD29308.1 - 1.2e-55 187.8 0.1 2.9e-55 186.5 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 PVD29308.1 - 1.2e-53 181.3 4.0 2.2e-49 167.4 0.2 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_9 PF12781.7 PVD29308.1 - 1.1e-52 178.4 7.1 8.1e-36 123.2 0.0 4.6 3 1 1 4 4 4 2 ATP-binding dynein motor region DHC_N1 PF08385.12 PVD29308.1 - 2.7e-41 141.9 0.1 2.7e-41 141.9 0.1 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 PVD29308.1 - 7e-41 140.4 12.6 7e-41 140.4 12.6 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD29308.1 - 3.6e-40 136.8 0.0 1.7e-39 134.6 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 PVD29308.1 - 9.3e-22 77.1 0.0 8.3e-21 74.1 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PVD29308.1 - 4.4e-19 68.9 0.0 2.4e-06 27.6 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PVD29308.1 - 1.1e-14 54.6 0.0 7.8e-14 51.9 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PVD29308.1 - 5e-06 27.0 0.1 5.1 7.5 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD29308.1 - 9.8e-05 22.6 2.8 19 5.5 0.0 5.6 5 0 0 5 5 5 0 AAA domain AAA_16 PF13191.6 PVD29308.1 - 0.0032 17.9 0.1 23 5.3 0.0 5.0 4 0 0 4 4 4 0 AAA ATPase domain ERK-JNK_inhib PF15002.6 PVD29308.1 - 0.0045 16.7 0.6 0.66 9.6 0.0 2.7 2 0 0 2 2 2 1 ERK and JNK pathways, inhibitor Sigma54_activat PF00158.26 PVD29308.1 - 0.017 14.8 0.0 2.1 8.0 0.0 3.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 PVD29308.1 - 0.068 13.4 1.3 21 5.4 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PVD29308.1 - 0.36 11.3 1.7 18 5.8 0.0 4.0 4 0 0 4 4 4 0 ABC transporter DHC_N1 PF08385.12 PVD29309.1 - 7.6e-109 364.9 5.0 7.6e-109 364.9 5.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 Methyltransf_11 PF08241.12 PVD29309.1 - 0.14 12.8 0.2 1.2 9.9 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain zf-C2H2 PF00096.26 PVD29310.1 - 5.4e-27 92.7 39.9 9.1e-05 22.7 1.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD29310.1 - 2e-21 75.4 37.9 1.5e-05 25.2 0.3 6.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD29310.1 - 4.1e-17 61.4 35.7 0.0078 17.0 0.9 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD29310.1 - 1.1e-08 35.2 19.9 0.00048 20.4 2.7 4.2 1 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PVD29310.1 - 0.019 15.0 35.5 0.23 11.5 0.3 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD29310.1 - 0.06 13.7 17.9 8.5 6.8 0.2 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 PVD29310.1 - 0.18 11.9 21.1 3 8.0 0.4 5.8 1 1 5 6 6 6 0 Aberrant zinc-finger zf_ZIC PF18366.1 PVD29310.1 - 0.21 11.7 16.7 21 5.3 0.1 6.0 5 1 1 6 6 6 0 Zic proteins zinc finger domain 40S_S4_C PF16121.5 PVD29311.1 - 1.1e-27 95.3 0.0 1.9e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus Ribosomal_S4e PF00900.20 PVD29311.1 - 2.5e-24 85.0 0.4 6.7e-24 83.6 0.4 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 PVD29311.1 - 4.8e-18 65.0 4.0 1.4e-17 63.5 4.0 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain KOW PF00467.29 PVD29311.1 - 8.1e-06 25.6 0.3 8.1e-06 25.6 0.3 2.2 3 0 0 3 3 3 1 KOW motif Malic_M PF03949.15 PVD29312.1 - 8.6e-80 267.7 0.1 2.1e-77 259.9 0.1 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PVD29312.1 - 1.3e-77 259.7 0.0 2.2e-77 259.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF384 PF04064.13 PVD29312.1 - 0.17 11.7 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Laminin_I PF06008.14 PVD29316.1 - 0.52 10.0 9.3 0.13 12.0 1.3 2.2 2 0 0 2 2 2 0 Laminin Domain I Spc24 PF08286.11 PVD29316.1 - 0.94 9.7 3.8 0.58 10.4 0.2 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 PVD29316.1 - 6.3 6.9 12.5 2.6 8.1 0.7 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WD40 PF00400.32 PVD29317.1 - 8.4e-36 121.4 15.0 3.7e-06 27.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD29317.1 - 1.3e-11 44.7 0.7 0.36 11.2 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PVD29317.1 - 0.0029 17.2 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 PQQ-like domain Na_K-ATPase PF00287.18 PVD29318.1 - 5e-16 58.7 0.0 6.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Big_9 PF17963.1 PVD29318.1 - 0.04 14.7 0.6 0.21 12.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig domain Lectin_C PF00059.21 PVD29319.1 - 9.7e-18 64.9 0.4 1.8e-17 64.0 0.4 1.4 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 PVD29319.1 - 0.035 13.4 0.3 0.046 13.0 0.3 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 PVD29320.1 - 4.9e-19 69.0 0.1 6.2e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD29321.1 - 7.8e-18 65.2 0.3 1.5e-17 64.3 0.3 1.5 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD29321.1 - 8.7e-06 25.5 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF780 PF05611.11 PVD29322.1 - 3.7 8.4 5.7 0.37 11.6 0.6 2.0 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) PLAC8 PF04749.17 PVD29324.1 - 5.7e-07 30.5 9.5 1.1e-06 29.5 9.5 1.5 1 1 0 1 1 1 1 PLAC8 family zf-C2H2 PF00096.26 PVD29325.1 - 1.2e-13 50.6 69.0 3.5e-06 27.2 2.7 9.4 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD29325.1 - 2e-11 43.8 53.5 5.9e-06 26.5 5.2 8.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD29325.1 - 2.7e-09 37.1 64.4 0.0014 19.3 1.6 9.6 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD29325.1 - 3.3e-05 23.6 1.1 3.3e-05 23.6 1.1 7.5 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-met PF12874.7 PVD29325.1 - 0.0014 19.0 0.4 0.0014 19.0 0.4 6.9 7 0 0 7 7 7 2 Zinc-finger of C2H2 type DUF5462 PF17547.2 PVD29325.1 - 0.0056 16.1 1.0 0.029 13.7 0.9 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5462) zf-C2H2_11 PF16622.5 PVD29325.1 - 0.023 14.4 1.0 0.023 14.4 1.0 4.4 6 0 0 6 6 6 0 zinc-finger C2H2-type AT_hook PF02178.19 PVD29325.1 - 3.1 8.0 20.0 5.2 7.3 5.7 2.6 2 0 0 2 2 2 0 AT hook motif Cyclin_N PF00134.23 PVD29328.1 - 2e-38 131.0 2.1 3.4e-38 130.2 2.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PVD29328.1 - 7.4e-23 80.9 2.3 5.4e-20 71.7 0.0 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain Exo_endo_phos PF03372.23 PVD29330.1 - 4.1e-09 36.3 0.0 1.7e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5365 PF17326.2 PVD29330.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) SNF2_N PF00176.23 PVD29332.1 - 4.3e-95 318.4 1.5 6.3e-95 317.8 1.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 PVD29332.1 - 0.00041 20.2 9.9 0.00041 20.2 9.9 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD29332.1 - 0.00045 20.5 11.6 0.00045 20.5 11.6 4.2 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 PVD29332.1 - 0.0005 19.9 10.3 0.0005 19.9 10.3 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD29332.1 - 0.0012 18.9 9.0 0.0012 18.9 9.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger TPR_12 PF13424.6 PVD29332.1 - 0.0042 17.4 0.4 0.032 14.5 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat PHD PF00628.29 PVD29332.1 - 0.0091 15.9 8.3 0.0091 15.9 8.3 3.5 3 0 0 3 3 2 1 PHD-finger Helicase_C PF00271.31 PVD29332.1 - 0.017 15.4 0.1 2.5 8.5 0.0 2.6 1 1 1 2 2 2 0 Helicase conserved C-terminal domain Prok-RING_1 PF14446.6 PVD29332.1 - 0.041 13.8 0.3 0.041 13.8 0.3 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 TPR_10 PF13374.6 PVD29332.1 - 0.048 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RasGEF_N PF00618.20 PVD29332.1 - 0.058 13.6 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 RasGEF N-terminal motif TPR_1 PF00515.28 PVD29332.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 PVD29332.1 - 8.9 6.6 23.3 0.039 14.1 9.0 3.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING HLH PF00010.26 PVD29337.1 - 9.4e-06 25.5 1.1 1.1e-05 25.2 1.1 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.12 PVD29339.1 - 3.4e-26 91.4 0.4 1.2e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 PVD29339.1 - 1.5e-19 70.2 0.2 9.2e-14 51.5 0.1 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 PVD29339.1 - 9.7e-16 57.8 0.0 1.6e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 PVD29339.1 - 0.00048 20.3 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 PVD29339.1 - 0.00096 19.4 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold SUIM_assoc PF16619.5 PVD29340.1 - 3.5 7.8 20.9 1.8 8.7 0.9 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 BIR PF00653.21 PVD29341.1 - 2.4e-24 85.8 16.0 2.4e-20 73.0 2.5 3.4 3 1 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD29341.1 - 3.4e-11 42.8 13.1 3.4e-11 42.8 13.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD29341.1 - 0.0003 20.6 11.5 0.001 18.9 11.5 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_2 PF12796.7 PVD29342.1 - 4.1e-20 72.1 3.5 1.1e-05 26.0 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD29342.1 - 3.2e-19 68.7 2.3 2e-06 28.0 0.0 7.1 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD29342.1 - 1.8e-14 53.8 4.9 7.9e-05 23.1 0.0 6.8 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29342.1 - 4.6e-11 41.9 5.8 0.53 11.0 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 PVD29342.1 - 5.3e-11 42.4 7.1 0.0035 17.7 0.1 7.3 9 0 0 9 9 9 2 Ankyrin repeat LPMO_10 PF03067.15 PVD29343.1 - 0.011 16.4 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 PVD29345.1 - 2.5e-26 93.5 0.9 3.8e-26 92.9 0.9 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sec63 PF02889.16 PVD29347.1 - 1.1e-147 490.1 0.1 1.5e-77 260.3 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PVD29347.1 - 1.8e-52 177.7 3.3 5.5e-27 94.7 0.5 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 PVD29347.1 - 2.4e-24 86.2 0.0 1.1e-11 45.1 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PVD29347.1 - 1.1e-15 57.9 0.1 2.1e-07 31.2 0.0 3.4 3 0 0 3 3 2 2 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 PVD29347.1 - 2.8e-10 40.4 0.0 2.8e-10 40.4 0.0 2.6 3 0 0 3 3 2 1 N-terminal helicase PWI domain AAA_22 PF13401.6 PVD29347.1 - 6.2e-07 29.8 1.5 0.0089 16.3 0.1 3.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PVD29347.1 - 1.5e-06 28.1 0.0 0.0042 16.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 PVD29347.1 - 0.00031 19.9 0.0 0.38 9.7 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 PVD29347.1 - 0.00051 20.4 0.5 0.29 11.4 0.4 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PVD29347.1 - 0.0025 17.3 0.2 0.41 10.1 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_7 PF12775.7 PVD29347.1 - 0.0033 17.0 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region UvrD-helicase PF00580.21 PVD29347.1 - 0.063 12.8 0.2 0.58 9.6 0.1 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 PVD29347.1 - 0.11 12.3 0.6 1 9.1 0.0 2.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.6 PVD29347.1 - 5 7.6 7.9 11 6.5 0.0 3.5 3 0 0 3 3 2 0 AAA domain EF-hand_7 PF13499.6 PVD29348.1 - 5e-21 74.9 13.4 3.8e-10 40.1 0.3 7.7 7 1 0 7 7 7 4 EF-hand domain pair EF-hand_8 PF13833.6 PVD29348.1 - 1.3e-16 60.2 8.4 5.9e-08 32.4 0.1 6.3 6 1 1 7 7 7 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD29348.1 - 1.7e-15 55.5 14.6 0.018 14.9 0.0 8.9 8 1 1 9 9 9 4 EF-hand domain EF-hand_1 PF00036.32 PVD29348.1 - 1.4e-14 52.5 9.8 0.0074 15.8 0.2 8.4 8 1 1 9 9 9 3 EF hand EF-hand_11 PF08976.11 PVD29348.1 - 2.4e-13 50.9 3.8 0.023 15.6 0.0 6.7 7 0 0 7 7 7 2 EF-hand domain DUF5580 PF17743.1 PVD29348.1 - 0.00081 18.1 0.3 0.44 9.0 0.0 3.2 3 0 0 3 3 3 1 Family of unknown function (DUF5580) THB PF18362.1 PVD29348.1 - 0.054 13.1 0.2 0.51 10.0 0.1 2.7 3 0 0 3 3 3 0 Tri-helix bundle domain EF-hand_9 PF14658.6 PVD29348.1 - 0.058 13.7 0.3 42 4.5 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 PVD29348.1 - 0.083 12.4 4.2 1.1 8.9 0.2 3.5 3 0 0 3 3 3 0 EF hand DEAD PF00270.29 PVD29354.1 - 3.4e-44 150.7 0.3 9.3e-44 149.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD29354.1 - 5.8e-25 87.8 0.5 3.3e-24 85.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VWA PF00092.28 PVD29354.1 - 4.7e-19 69.3 0.0 1.2e-18 68.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4217 PF13959.6 PVD29354.1 - 1.9e-17 63.2 0.1 4.4e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PVD29354.1 - 5.4e-07 29.8 0.0 1.9e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VWA_2 PF13519.6 PVD29354.1 - 3.7e-06 27.6 0.0 3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Baculo_gp41 PF04700.12 PVD29354.1 - 0.029 14.1 0.1 0.074 12.8 0.1 1.7 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region 7tm_2 PF00002.24 PVD29355.1 - 7.3e-49 166.3 23.6 1.3e-48 165.4 23.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cadherin PF00028.17 PVD29355.1 - 4.6e-26 91.1 17.4 0.00089 19.7 0.0 8.6 8 1 0 8 8 8 5 Cadherin domain GPS PF01825.21 PVD29355.1 - 2.1e-12 47.3 3.2 7.5e-12 45.6 3.2 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 PVD29355.1 - 1.1e-10 41.3 1.3 2.3e-10 40.3 1.3 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain fn3 PF00041.21 PVD29355.1 - 1.8e-06 28.2 1.1 1.2e-05 25.5 0.6 2.8 2 0 0 2 2 2 1 Fibronectin type III domain SQAPI PF16845.5 PVD29355.1 - 0.039 14.3 0.2 1.5 9.2 0.1 3.1 3 0 0 3 3 3 0 Aspartic acid proteinase inhibitor SusE PF14292.6 PVD29355.1 - 0.14 12.4 4.6 0.15 12.3 0.3 3.4 3 0 0 3 3 3 0 SusE outer membrane protein Big_9 PF17963.1 PVD29355.1 - 7 7.5 59.3 0.018 15.8 2.8 8.3 7 1 1 8 8 8 0 Bacterial Ig domain LOH1CR12 PF10158.9 PVD29359.1 - 6.1e-35 120.1 1.1 8.2e-35 119.7 1.1 1.2 1 0 0 1 1 1 1 Tumour suppressor protein Uteroglobin PF01099.17 PVD29359.1 - 0.028 14.7 0.5 0.053 13.9 0.4 1.4 1 1 0 1 1 1 0 Uteroglobin family RhoGEF PF00621.20 PVD29359.1 - 0.037 14.3 0.2 0.058 13.6 0.2 1.3 1 0 0 1 1 1 0 RhoGEF domain BLOC1_2 PF10046.9 PVD29359.1 - 0.048 13.9 0.7 0.087 13.1 0.7 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 PVD29359.1 - 0.086 12.9 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Terminase_4 PF05119.12 PVD29359.1 - 0.14 12.6 0.2 0.42 11.1 0.2 1.9 1 1 1 2 2 2 0 Phage terminase, small subunit POX PF07526.11 PVD29359.1 - 0.19 12.3 1.0 0.24 12.0 0.3 1.5 2 0 0 2 2 2 0 Associated with HOX DUF2841 PF11001.8 PVD29359.1 - 0.57 10.3 3.5 0.42 10.7 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2841) DUF4452 PF14618.6 PVD29359.1 - 2.4 8.0 5.6 0.86 9.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) SAPS PF04499.15 PVD29360.1 - 1.2e-85 288.2 9.5 2.2e-54 185.0 1.0 3.1 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein NPH3 PF03000.14 PVD29360.1 - 0.0049 16.6 0.2 0.013 15.2 0.1 1.7 2 0 0 2 2 2 1 NPH3 family HEAT_2 PF13646.6 PVD29360.1 - 0.03 14.7 0.1 0.26 11.7 0.1 2.3 1 1 0 1 1 1 0 HEAT repeats Macro PF01661.21 PVD29361.1 - 9.4e-46 154.7 0.2 6.8e-29 100.3 0.2 3.7 3 0 0 3 3 3 3 Macro domain SCAN PF02023.17 PVD29361.1 - 2.5e-13 49.6 0.6 1e-12 47.7 0.6 2.2 1 0 0 1 1 1 1 SCAN domain Neurokinin_B PF03823.14 PVD29361.1 - 0.1 12.7 1.3 0.34 11.0 1.3 1.9 1 0 0 1 1 1 0 Neurokinin B zf-RING_2 PF13639.6 PVD29362.1 - 1.3e-08 35.0 13.9 1.3e-08 35.0 13.9 3.5 4 1 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 PVD29362.1 - 0.0001 21.9 14.1 0.0001 21.9 14.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PVD29362.1 - 0.00052 20.2 13.1 0.00052 20.2 13.1 4.0 5 1 0 5 5 5 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PVD29362.1 - 0.0028 17.4 13.7 0.0028 17.4 13.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HeH PF12949.7 PVD29362.1 - 0.01 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain zf-RING_UBOX PF13445.6 PVD29362.1 - 3.2 7.8 20.3 0.22 11.6 13.2 2.8 2 1 0 2 2 2 0 RING-type zinc-finger HscB_4_cys PF18256.1 PVD29362.1 - 5.5 6.9 8.1 0.4 10.5 2.1 2.3 2 1 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif NRBF2 PF08961.10 PVD29363.1 - 1.4e-08 34.6 9.8 3.4e-08 33.3 1.8 2.7 1 1 1 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator CENP-F_leu_zip PF10473.9 PVD29363.1 - 0.014 15.4 3.1 0.014 15.4 3.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAT PF03127.14 PVD29363.1 - 0.034 14.5 0.1 0.034 14.5 0.1 2.5 3 1 0 3 3 3 0 GAT domain Microtub_bind PF13931.6 PVD29363.1 - 0.11 12.9 3.4 0.93 9.9 0.2 2.4 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Fungal_TACC PF12709.7 PVD29363.1 - 0.43 11.0 4.2 0.29 11.6 0.3 2.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 PVD29363.1 - 1.2 9.6 9.1 0.087 13.4 2.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PVD29363.1 - 8.9 6.6 12.7 0.48 10.7 0.4 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DTC PF18102.1 PVD29364.1 - 7.1e-35 120.0 0.0 7.9e-29 100.5 0.0 2.5 1 1 1 2 2 2 2 Deltex C-terminal domain Macro PF01661.21 PVD29364.1 - 1.2e-21 76.9 0.0 3.2e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Macro domain zf-C3HC4_2 PF13923.6 PVD29364.1 - 7.2e-09 35.3 12.4 2.2e-08 33.8 12.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD29364.1 - 3.1e-08 33.8 9.7 3.1e-08 33.8 9.7 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD29364.1 - 2.5e-07 30.6 12.0 2.5e-07 30.6 12.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD29364.1 - 2.6e-07 30.4 7.8 2.6e-07 30.4 7.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD29364.1 - 4.2e-07 30.0 10.6 4.2e-07 30.0 10.6 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD29364.1 - 3.5e-06 26.8 11.7 3.5e-06 26.8 11.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 PVD29364.1 - 2.2e-05 24.5 7.2 8.5e-05 22.6 7.2 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 PVD29364.1 - 0.00011 22.1 10.1 0.00011 22.1 10.1 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD29364.1 - 0.0014 18.8 7.5 0.0014 18.8 7.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PVD29364.1 - 0.026 14.3 10.1 0.11 12.2 10.4 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PVD29364.1 - 0.049 13.5 13.2 0.89 9.5 13.2 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD29364.1 - 0.15 11.8 4.6 0.54 10.1 4.6 2.0 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 PVD29364.1 - 1.9 8.5 13.5 20 5.3 13.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon Amino_oxidase PF01593.24 PVD29367.1 - 3.6e-75 254.0 0.0 4.9e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD29367.1 - 8.7e-13 48.3 0.1 1.7e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PVD29367.1 - 0.00084 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PVD29367.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PVD29367.1 - 0.0014 18.0 0.5 0.0025 17.1 0.5 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 PVD29367.1 - 0.0079 16.2 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PVD29367.1 - 0.0085 15.4 0.5 0.016 14.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD29367.1 - 0.011 14.8 0.3 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 PVD29367.1 - 0.018 13.7 0.1 0.06 12.0 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 PVD29367.1 - 0.024 15.2 0.1 0.074 13.6 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PVD29367.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PVD29367.1 - 0.046 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 PVD29367.1 - 0.11 10.8 0.1 0.17 10.2 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DDRGK PF09756.9 PVD29369.1 - 4.4e-64 215.6 30.7 4.4e-64 215.6 30.7 1.6 2 0 0 2 2 2 1 DDRGK domain FeoC PF09012.10 PVD29369.1 - 0.00061 19.8 0.2 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 FeoC like transcriptional regulator RNA_polI_A34 PF08208.11 PVD29369.1 - 0.072 13.2 22.5 0.12 12.4 22.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Draxin PF15550.6 PVD29369.1 - 0.12 12.2 14.2 0.15 11.9 14.2 1.1 1 0 0 1 1 1 0 Draxin DDHD PF02862.17 PVD29369.1 - 0.15 12.2 2.3 0.18 11.9 2.3 1.4 1 0 0 1 1 1 0 DDHD domain Nop53 PF07767.11 PVD29369.1 - 0.15 11.4 34.7 0.22 10.8 34.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.9 PVD29369.1 - 0.27 9.7 6.7 0.3 9.5 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 PVD29369.1 - 0.33 10.9 12.5 0.46 10.4 12.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4604 PF15377.6 PVD29369.1 - 0.34 11.3 26.7 0.48 10.8 26.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Nop14 PF04147.12 PVD29369.1 - 0.38 8.9 30.7 0.47 8.6 30.7 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 PVD29369.1 - 0.93 9.3 21.6 1.5 8.6 21.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PVD29369.1 - 1.5 7.5 13.7 1.9 7.2 13.7 1.2 1 0 0 1 1 1 0 Presenilin DUF3347 PF11827.8 PVD29369.1 - 2.4 8.3 18.9 2 8.6 17.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Hid1 PF12722.7 PVD29369.1 - 4.2 5.4 11.4 4.7 5.2 11.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 PVD29369.1 - 4.4 5.1 10.8 5 4.9 10.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 PVD29369.1 - 7.4 6.3 15.7 11 5.7 15.7 1.3 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 PVD29369.1 - 7.5 5.2 16.7 10 4.8 16.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RhoGAP PF00620.27 PVD29370.1 - 3.8e-24 85.3 0.5 8.2e-24 84.2 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain Tae4 PF14113.6 PVD29371.1 - 1.3e-07 31.9 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase effector protein 4 RVT_1 PF00078.27 PVD29372.1 - 1.1e-19 70.8 0.0 1.4e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ETC_C1_NDUFA5 PF04716.14 PVD29373.1 - 1.9e-06 27.6 3.4 18 5.2 0.0 6.5 7 0 0 7 7 7 2 ETC complex I subunit conserved region C4bp_oligo PF18453.1 PVD29373.1 - 0.00032 20.8 8.4 83 3.5 0.0 6.1 6 0 0 6 6 6 0 Oligomerization domain of C4b-binding protein alpha RHIM PF12721.7 PVD29373.1 - 0.00065 20.1 6.1 51 4.5 0.2 6.7 6 2 0 6 6 6 0 RIP homotypic interaction motif MRF_C1 PF13887.6 PVD29373.1 - 0.00068 18.7 0.9 90 2.3 0.0 5.4 6 0 0 6 6 6 0 Myelin gene regulatory factor -C-terminal domain 1 Rrf2 PF02082.20 PVD29373.1 - 0.0022 18.3 1.0 1.2e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 Transcriptional regulator DUF3247 PF11607.8 PVD29373.1 - 0.0028 17.9 3.1 44 4.4 0.0 5.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3247) Colipase-like PF15083.6 PVD29374.1 - 8.1e-12 45.1 41.2 1.7 8.8 2.3 13.7 4 3 13 17 17 17 10 Colipase-like Lectin_C PF00059.21 PVD29376.1 - 1.1e-07 32.6 0.0 2.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD29377.1 - 4.2e-15 56.4 0.8 5.6e-15 56.0 0.8 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD29378.1 - 1.2e-16 61.4 0.4 2e-16 60.6 0.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF4573 PF15140.6 PVD29379.1 - 1.1e-21 77.4 20.5 3.9e-12 46.3 6.4 3.6 1 1 1 3 3 3 3 Domain of unknown function (DUF4573) NUT PF12881.7 PVD29379.1 - 2.8e-07 29.4 30.8 0.0032 16.0 4.4 3.5 1 1 1 3 3 3 3 NUT protein Glutenin_hmw PF03157.13 PVD29379.1 - 0.19 10.1 61.0 2.3 6.6 61.0 2.0 1 1 0 1 1 1 0 High molecular weight glutenin subunit Amelogenin PF02948.15 PVD29379.1 - 1.8 9.2 37.6 2.5 8.7 6.9 3.3 1 1 2 3 3 3 0 Amelogenin Exo_endo_phos_2 PF14529.6 PVD29380.1 - 0.00069 19.5 0.6 0.0035 17.2 0.6 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Lectin_C PF00059.21 PVD29381.1 - 5.4e-08 33.5 0.5 9.4e-08 32.8 0.5 1.4 1 0 0 1 1 1 1 Lectin C-type domain RVT_1 PF00078.27 PVD29381.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lectin_C PF00059.21 PVD29382.1 - 1.1e-17 64.8 1.7 1.1e-17 64.7 0.4 1.6 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.12 PVD29382.1 - 6.1e-05 22.7 0.0 6.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like 7tm_1 PF00001.21 PVD29384.1 - 8.3e-79 264.6 0.1 1.3e-78 264.0 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29384.1 - 5.3e-10 39.1 12.9 6e-06 25.8 10.2 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD29384.1 - 7.1e-05 22.6 11.1 0.00017 21.3 11.1 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD29384.1 - 0.014 15.1 11.2 0.019 14.7 7.0 2.4 2 1 0 2 2 2 0 Olfactory receptor DUF3671 PF12420.8 PVD29384.1 - 8.7 6.5 6.6 9.6 6.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function 7tm_1 PF00001.21 PVD29386.1 - 6.6e-77 258.4 21.0 8.5e-77 258.0 21.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29386.1 - 2e-10 40.5 20.6 2.6e-10 40.1 20.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD29386.1 - 1.2e-06 28.3 14.0 1.2e-06 28.3 14.0 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD29386.1 - 0.00011 22.1 18.0 0.0056 16.5 18.0 2.6 1 1 0 1 1 1 1 Olfactory receptor Ni_hydr_CYTB PF01292.20 PVD29386.1 - 0.0045 16.6 4.0 0.33 10.5 1.1 2.3 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 Git3 PF11710.8 PVD29386.1 - 0.064 13.0 13.2 0.13 12.0 13.2 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Prolamin_like PF05617.11 PVD29387.1 - 0.099 12.8 0.6 1.1 9.5 0.6 2.3 1 1 1 2 2 2 0 Prolamin-like Cmc1 PF08583.10 PVD29387.1 - 0.74 9.9 3.4 14 5.8 0.1 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Hyd_WA PF06462.12 PVD29389.1 - 8e-15 54.5 18.9 1.6e-07 31.2 2.0 5.8 5 2 0 5 5 5 4 Propeller Hyd_WA PF06462.12 PVD29390.1 - 7e-17 61.1 13.9 0.00015 21.7 0.7 5.7 6 0 0 6 6 6 4 Propeller CCDC53 PF10152.9 PVD29390.1 - 0.0029 18.0 0.3 0.0036 17.8 0.3 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Coilin_N PF15862.5 PVD29390.1 - 0.0047 16.7 0.2 0.0062 16.3 0.2 1.2 1 0 0 1 1 1 1 Coilin N-terminus RcnB PF11776.8 PVD29390.1 - 0.0077 16.3 0.9 8.8 6.5 0.1 3.8 4 0 0 4 4 4 1 Nickel/cobalt transporter regulator Spt20 PF12090.8 PVD29390.1 - 0.1 12.2 22.9 0.13 11.8 22.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 PVD29390.1 - 0.36 11.8 7.1 0.66 11.0 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 PVD29390.1 - 1.2 9.1 19.0 1.5 8.7 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PVD29390.1 - 1.2 8.0 22.2 1.7 7.5 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 PVD29390.1 - 1.3 8.9 9.5 1.7 8.5 9.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 PVD29390.1 - 2.9 7.6 5.5 4.7 6.9 5.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 PVD29390.1 - 3.4 5.4 15.2 5 4.9 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.13 PVD29390.1 - 3.6 8.2 15.2 6 7.5 15.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 PVD29390.1 - 4.6 5.9 6.8 6.6 5.4 6.8 1.2 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 PVD29390.1 - 4.8 6.9 9.2 12 5.7 8.5 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Hyd_WA PF06462.12 PVD29391.1 - 1e-20 73.4 34.4 1.6e-08 34.4 0.6 6.4 7 0 0 7 7 7 5 Propeller RcnB PF11776.8 PVD29391.1 - 0.0063 16.5 2.9 5.3 7.2 0.0 4.9 5 0 0 5 5 5 1 Nickel/cobalt transporter regulator Hyd_WA PF06462.12 PVD29392.1 - 1.2e-26 92.4 25.0 1.5e-07 31.2 2.7 6.0 6 0 0 6 6 6 5 Propeller PIN_11 PF18479.1 PVD29392.1 - 0.082 13.1 1.4 8.4 6.6 0.2 2.5 2 0 0 2 2 2 0 PIN like domain Hyd_WA PF06462.12 PVD29393.1 - 6.5e-26 90.0 32.9 1.4e-08 34.6 1.2 6.8 6 1 0 6 6 6 5 Propeller Sugar_transport PF06800.12 PVD29393.1 - 1.8 7.8 7.8 6 6.1 0.1 2.6 3 0 0 3 3 3 0 Sugar transport protein Lectin_leg-like PF03388.13 PVD29394.1 - 1.2e-81 273.4 0.4 1.6e-81 273.1 0.4 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 PVD29394.1 - 1.7e-07 31.5 0.0 2.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin Laminin_G_2 PF02210.24 PVD29394.1 - 0.052 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Laminin G domain Lectin_legB PF00139.19 PVD29394.1 - 0.066 12.7 0.0 4.9 6.6 0.0 2.2 1 1 1 2 2 2 0 Legume lectin domain ABC_membrane PF00664.23 PVD29394.1 - 0.096 12.3 0.8 1.9 8.1 0.5 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region 4HB_MCP_1 PF12729.7 PVD29394.1 - 0.19 11.3 0.6 0.28 10.7 0.6 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2140 PF09911.9 PVD29394.1 - 0.23 11.0 0.3 0.39 10.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF872 PF05915.12 PVD29395.1 - 6.6e-18 65.0 1.5 7.6e-18 64.8 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Phage_holin_3_6 PF07332.11 PVD29395.1 - 0.016 15.2 4.2 0.02 14.9 4.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 PVD29395.1 - 0.25 11.7 3.8 0.44 10.9 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Hexokinase_2 PF03727.16 PVD29396.1 - 0.00013 21.5 0.3 0.00017 21.1 0.3 1.1 1 0 0 1 1 1 1 Hexokinase CC2-LZ PF16516.5 PVD29397.1 - 9.9e-10 38.7 10.1 9.9e-10 38.7 10.1 5.5 3 2 3 6 6 6 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator EABR PF12180.8 PVD29397.1 - 0.00012 21.6 3.0 0.00028 20.4 3.0 1.7 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 Lebercilin PF15619.6 PVD29397.1 - 0.0019 17.9 16.5 0.0019 17.9 16.5 5.2 2 1 2 5 5 5 3 Ciliary protein causing Leber congenital amaurosis disease Rad50_zn_hook PF04423.14 PVD29397.1 - 0.012 15.4 0.6 0.012 15.4 0.6 3.9 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 PVD29397.1 - 0.068 14.0 0.4 0.33 11.9 0.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger DUF5082 PF16888.5 PVD29397.1 - 1.2 9.5 29.6 0.41 10.9 9.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5082) SH3_3 PF08239.11 PVD29398.1 - 6.1e-23 80.9 0.1 4e-09 36.6 0.1 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_4 PF06347.13 PVD29398.1 - 1.5e-05 24.7 0.3 0.023 14.5 0.5 3.5 3 1 0 3 3 3 1 Bacterial SH3 domain Tudor_RapA PF18337.1 PVD29398.1 - 2.5e-05 24.4 0.2 2.4 8.4 0.0 3.3 3 0 0 3 3 3 3 RapA N-terminal Tudor like domain Amidase_2 PF01510.25 PVD29398.1 - 0.0079 16.6 6.0 0.33 11.4 0.0 3.1 2 2 1 3 3 3 2 N-acetylmuramoyl-L-alanine amidase Diedel PF13164.6 PVD29398.1 - 0.008 16.6 4.9 0.039 14.4 0.5 3.8 1 1 2 3 3 3 1 Diedel WHH PF14414.6 PVD29398.1 - 0.06 13.2 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH HisG PF01634.18 PVD29398.1 - 0.16 11.9 0.8 17 5.4 0.0 2.5 2 1 1 3 3 3 0 ATP phosphoribosyltransferase RANK_CRD_2 PF18278.1 PVD29398.1 - 6.4 7.0 7.7 15 5.8 0.1 3.8 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Amidase_2 PF01510.25 PVD29399.1 - 2e-07 31.5 0.3 2.8e-07 31.1 0.3 1.4 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase SH3_3 PF08239.11 PVD29399.1 - 0.00036 20.7 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_2 PF01510.25 PVD29400.1 - 3.5e-35 121.2 3.7 7.7e-18 65.2 0.4 2.4 2 0 0 2 2 2 2 N-acetylmuramoyl-L-alanine amidase SH3_3 PF08239.11 PVD29400.1 - 6.3e-10 39.2 0.7 2.4e-07 30.9 0.8 4.2 5 1 0 5 5 5 2 Bacterial SH3 domain SH3_4 PF06347.13 PVD29400.1 - 3 7.7 8.2 0.84 9.5 0.8 3.3 3 1 0 3 3 3 0 Bacterial SH3 domain SH3_3 PF08239.11 PVD29401.1 - 0.0026 18.0 0.6 0.0034 17.6 0.6 1.2 1 0 0 1 1 1 1 Bacterial SH3 domain COX2_TM PF02790.15 PVD29401.1 - 0.044 13.9 1.0 0.059 13.5 1.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DuoxA PF10204.9 PVD29401.1 - 0.1 11.6 2.7 0.13 11.2 2.7 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor ResIII PF04851.15 PVD29402.1 - 1.5e-20 73.9 0.0 6e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 PVD29402.1 - 1.5e-17 63.9 0.1 3.2e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 PVD29402.1 - 1.5e-16 60.7 0.2 1.5e-16 60.7 0.2 2.2 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain DEAD PF00270.29 PVD29402.1 - 2.8e-16 59.8 0.0 2e-15 57.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD29402.1 - 3.8e-15 56.2 0.2 1.2e-14 54.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PVD29402.1 - 6.1e-05 23.4 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain SWI2_SNF2 PF18766.1 PVD29402.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 PVD29402.1 - 0.0031 17.0 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein CheY-binding PF09078.11 PVD29402.1 - 0.0064 16.6 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 CheY binding AAA_22 PF13401.6 PVD29402.1 - 0.046 14.0 0.0 0.19 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 PVD29402.1 - 0.11 11.3 0.0 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein CARD_2 PF16739.5 PVD29402.1 - 0.11 12.5 0.0 8.4 6.5 0.0 3.4 3 0 0 3 3 3 0 Caspase recruitment domain ResIII PF04851.15 PVD29403.1 - 4.6e-23 82.1 0.0 1.4e-22 80.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 PVD29403.1 - 1e-22 80.5 4.6 2.7e-22 79.2 4.6 1.8 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.29 PVD29403.1 - 9.4e-19 67.8 0.1 6.1e-18 65.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase RIG-I_C PF18119.1 PVD29403.1 - 4.3e-16 59.2 2.5 4.3e-16 59.2 2.5 2.5 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain Helicase_C PF00271.31 PVD29403.1 - 7.9e-16 58.4 0.1 2.8e-14 53.4 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PVD29403.1 - 3.1e-09 37.3 0.0 0.00018 21.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain SWI2_SNF2 PF18766.1 PVD29403.1 - 6.1e-05 22.8 0.1 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_11 PF13086.6 PVD29403.1 - 0.00021 21.1 3.7 0.00065 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PVD29403.1 - 0.0026 17.2 0.0 0.024 14.1 0.0 2.6 2 1 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 PVD29403.1 - 0.0096 15.7 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Not3 PF04065.15 PVD29403.1 - 0.089 12.2 12.6 0.24 10.8 5.4 2.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component UvrD-helicase PF00580.21 PVD29403.1 - 0.19 11.2 6.5 0.19 11.2 0.6 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DNApol3-delta_C PF09115.10 PVD29403.1 - 2.5 8.6 6.5 30 5.2 0.4 3.6 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal DUF778 PF05608.12 PVD29403.1 - 2.5 8.4 4.0 6.5 7.1 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF778) VWC PF00093.18 PVD29404.1 - 0.15 12.4 86.1 0.12 12.7 18.5 5.1 5 1 0 5 5 5 0 von Willebrand factor type C domain Herpes_BLLF1 PF05109.13 PVD29407.1 - 1 7.2 314.8 0.023 12.7 35.2 8.9 1 1 8 9 9 9 0 Herpes virus major outer envelope glycoprotein (BLLF1) PI3_PI4_kinase PF00454.27 PVD29409.1 - 4.9e-60 203.4 0.0 6.4e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 PVD29409.1 - 0.075 12.9 5.2 0.13 12.1 5.2 1.3 1 0 0 1 1 1 0 Janus-atracotoxin FF PF01846.19 PVD29410.1 - 6.3e-70 231.2 50.7 6.6e-15 55.0 2.7 6.5 6 0 0 6 6 6 6 FF domain WW PF00397.26 PVD29410.1 - 1.5e-23 82.6 20.8 5.5e-08 32.8 4.5 4.1 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 PVD29410.1 - 0.0028 18.3 28.0 0.0028 18.3 2.2 5.1 3 2 1 4 4 4 3 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 PVD29410.1 - 0.053 13.8 12.6 1.7 8.9 3.3 4.4 4 1 1 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain Glyco_hydro_20 PF00728.22 PVD29411.1 - 1.3e-06 28.1 0.5 4.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20 PF00728.22 PVD29412.1 - 6e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20 PF00728.22 PVD29413.1 - 3.2e-07 30.1 3.7 3.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 PVD29413.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) DRMBL PF07522.14 PVD29414.1 - 7.8e-29 100.1 0.0 2.4e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 PVD29414.1 - 0.00076 19.1 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD29414.1 - 0.036 14.1 0.3 0.087 12.8 0.3 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily ETF PF01012.21 PVD29414.1 - 0.16 11.8 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain bZIP_1 PF00170.21 PVD29416.1 - 0.0039 17.3 5.4 0.015 15.4 5.4 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD29416.1 - 0.045 13.8 3.7 0.15 12.1 3.7 1.9 1 0 0 1 1 1 0 Basic region leucine zipper DUF2681 PF10883.8 PVD29416.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) bZIP_Maf PF03131.17 PVD29416.1 - 4.6 7.8 10.2 0.19 12.2 2.4 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Peptidase_S10 PF00450.22 PVD29417.1 - 1.9e-86 291.1 1.9 2.6e-86 290.7 1.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 PVD29417.1 - 0.089 13.4 0.0 0.3 11.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family 7tm_2 PF00002.24 PVD29418.1 - 8.7e-69 231.5 21.6 1.1e-68 231.2 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) zf-TRAF_2 PF15965.5 PVD29419.1 - 0.021 15.2 0.8 0.048 14.1 0.8 1.5 1 0 0 1 1 1 0 TRAF-like zinc-finger M_domain PF12938.7 PVD29419.1 - 0.036 13.9 0.3 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 M domain of GW182 Polysacc_synt_C PF14667.6 PVD29421.1 - 0.016 15.2 0.6 0.016 15.2 0.6 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Arm PF00514.23 PVD29422.1 - 1.9e-35 119.8 22.3 3.8e-08 33.1 0.0 9.0 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD29422.1 - 1.1e-11 44.9 15.9 0.0062 16.9 0.6 5.7 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 PVD29422.1 - 2.1e-11 43.0 9.7 0.045 14.0 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 PVD29422.1 - 2.7e-11 43.8 0.9 0.034 14.2 0.0 4.8 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 PVD29422.1 - 5e-08 32.9 0.2 0.35 10.6 0.0 4.0 2 1 1 4 4 4 3 DNA alkylation repair enzyme HEAT_EZ PF13513.6 PVD29422.1 - 3.1e-07 30.7 16.6 0.013 16.0 0.9 6.5 4 2 3 7 7 7 3 HEAT-like repeat CHASE6_C PF17150.4 PVD29422.1 - 1.9e-05 25.3 0.8 18 6.1 0.0 6.3 6 0 0 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 PVD29422.1 - 2.3e-05 23.1 2.0 0.0011 17.5 0.2 2.9 1 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 PVD29422.1 - 0.00012 20.8 6.0 0.11 11.0 0.7 3.5 2 1 0 3 3 3 3 Adaptin N terminal region RICTOR_V PF14668.6 PVD29422.1 - 0.0033 17.6 0.0 2.2 8.6 0.0 4.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RTP1_C1 PF10363.9 PVD29422.1 - 0.022 14.9 0.6 0.22 11.7 0.2 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 PVD29422.1 - 0.026 15.2 5.5 12 6.9 0.1 4.5 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat CelTOS PF18659.1 PVD29422.1 - 0.19 12.2 1.4 30 5.1 0.1 2.9 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites API5 PF05918.11 PVD29422.1 - 0.25 10.1 4.7 7.8 5.2 0.6 3.3 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) DUF3731 PF12531.8 PVD29422.1 - 0.26 11.1 5.5 4.7 7.0 0.2 3.2 3 0 0 3 3 3 0 DNA-K related protein Mid2 PF04478.12 PVD29422.1 - 0.34 10.7 4.5 0.49 10.2 1.8 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Longin_2 PF18639.1 PVD29422.1 - 0.47 10.3 5.2 12 5.8 0.2 3.0 3 0 0 3 3 3 0 Yeast longin domain COMM_domain PF07258.14 PVD29423.1 - 4.1e-19 68.5 0.1 5.7e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 COMM domain EMP24_GP25L PF01105.24 PVD29424.1 - 1.5e-50 171.7 0.3 1.8e-50 171.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF658 PF04936.12 PVD29424.1 - 0.011 15.4 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) SdrD_B PF17210.3 PVD29424.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 SdrD B-like domain Macro PF01661.21 PVD29425.1 - 9.2e-56 187.0 0.3 9.8e-26 90.1 0.0 3.9 3 0 0 3 3 3 3 Macro domain PARP PF00644.20 PVD29425.1 - 2.7e-26 92.4 1.8 5.4e-25 88.1 1.0 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain NID PF07292.13 PVD29425.1 - 3.4e-06 27.6 18.1 1.3 9.7 0.2 8.2 8 2 1 9 9 9 3 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 PVD29425.1 - 2.2e-05 24.2 2.8 0.16 11.8 0.0 5.4 5 1 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWE PF02825.20 PVD29425.1 - 0.00014 22.4 0.5 0.00046 20.7 0.5 2.0 1 0 0 1 1 1 1 WWE domain Nup35_RRM_2 PF14605.6 PVD29425.1 - 0.031 14.3 0.0 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SAM_2 PF07647.17 PVD29425.1 - 0.061 13.4 0.0 0.29 11.3 0.0 2.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Com_YlbF PF06133.11 PVD29425.1 - 5.4 7.7 11.7 2.1 9.0 1.9 3.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Macro PF01661.21 PVD29426.1 - 2.4e-59 198.5 0.4 8.4e-32 109.7 0.1 4.5 3 0 0 3 3 3 3 Macro domain PARP PF00644.20 PVD29426.1 - 3.5e-24 85.5 0.4 5.3e-23 81.6 0.4 3.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29426.1 - 3.6e-08 33.9 0.1 2e-07 31.5 0.1 2.4 1 0 0 1 1 1 1 WWE domain RRM_1 PF00076.22 PVD29426.1 - 0.0023 17.7 0.0 0.03 14.1 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A PF00476.20 PVD29427.1 - 3.9e-110 368.4 0.1 3.9e-110 368.4 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 PVD29427.1 - 8.5e-05 22.1 1.0 0.003 17.0 0.4 2.7 1 1 1 2 2 2 2 DNA polymerase nu pseudo-exo IBV_3A PF03617.13 PVD29427.1 - 0.0021 18.0 1.0 0.0063 16.5 1.0 1.8 1 0 0 1 1 1 1 IBV 3A protein Macro PF01661.21 PVD29428.1 - 1.5e-25 89.5 0.0 5.1e-25 87.8 0.0 2.0 1 0 0 1 1 1 1 Macro domain Biotin_carb_C PF02785.19 PVD29428.1 - 0.089 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain PARP PF00644.20 PVD29429.1 - 2e-25 89.5 0.1 1.6e-24 86.6 0.1 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29429.1 - 0.0001 22.8 0.0 0.00041 20.9 0.0 2.1 1 0 0 1 1 1 1 WWE domain SLS PF14611.6 PVD29429.1 - 0.0041 17.0 1.0 0.0041 17.0 1.0 2.4 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator APC_u13 PF16634.5 PVD29429.1 - 0.043 13.7 0.4 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr and SAMP ART-PolyVal PF18760.1 PVD29429.1 - 0.25 12.4 2.4 3.5 8.7 0.0 3.3 3 0 0 3 3 3 0 ADP-Ribosyltransferase in polyvalent proteins Macro PF01661.21 PVD29431.1 - 1.3e-33 115.5 0.0 8e-17 61.4 0.0 3.8 4 0 0 4 4 4 2 Macro domain PARP PF00644.20 PVD29431.1 - 3.8e-22 78.8 0.6 2.4e-21 76.2 0.6 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29431.1 - 0.0019 18.7 0.2 0.0067 17.0 0.2 2.0 1 0 0 1 1 1 1 WWE domain PARP PF00644.20 PVD29432.1 - 1.4e-06 28.0 0.1 5.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29432.1 - 0.001 19.6 0.1 0.0047 17.5 0.1 2.3 1 0 0 1 1 1 1 WWE domain Tub PF01167.18 PVD29432.1 - 0.013 15.3 0.1 0.058 13.1 0.1 2.1 1 0 0 1 1 1 0 Tub family NID PF07292.13 PVD29432.1 - 0.015 15.9 3.8 15 6.3 0.0 5.0 4 1 1 5 5 5 0 Nmi/IFP 35 domain (NID) PARP PF00644.20 PVD29433.1 - 1.7e-25 89.8 1.8 1.7e-24 86.5 1.8 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SBP56 PF05694.11 PVD29433.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Macro PF01661.21 PVD29434.1 - 1.4e-27 96.0 0.2 1.1e-26 93.2 0.0 2.7 2 0 0 2 2 2 1 Macro domain UN_NPL4 PF11543.8 PVD29434.1 - 1.5 9.4 4.9 8.1 7.0 0.3 3.1 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Macro PF01661.21 PVD29437.1 - 1.3e-35 122.0 0.4 6.6e-18 64.9 0.0 2.8 3 0 0 3 3 3 2 Macro domain PARP PF00644.20 PVD29437.1 - 2.2e-24 86.1 1.1 1.2e-23 83.7 1.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF982 PF06169.12 PVD29437.1 - 0.075 13.1 0.0 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF982) PARP PF00644.20 PVD29438.1 - 5.7e-23 81.5 0.0 5.7e-22 78.3 0.0 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD29438.1 - 8.2e-17 61.3 0.0 1.9e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Macro domain WWE PF02825.20 PVD29438.1 - 2.1e-06 28.2 2.4 1.2e-05 25.8 0.2 3.2 2 0 0 2 2 2 1 WWE domain RRM_1 PF00076.22 PVD29438.1 - 0.0026 17.5 0.0 0.12 12.3 0.0 3.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3107 PF11305.8 PVD29438.1 - 0.052 13.8 0.4 1.7 9.0 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Nup35_RRM_2 PF14605.6 PVD29439.1 - 2.4e-10 40.2 0.3 0.0075 16.3 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 PVD29439.1 - 1.7e-06 27.8 1.6 3.5 7.5 0.3 5.5 5 1 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 PVD29439.1 - 4.3e-06 27.3 5.0 0.15 12.7 0.1 6.2 5 2 2 7 7 7 1 Nmi/IFP 35 domain (NID) DUF2808 PF10989.8 PVD29439.1 - 0.0012 18.9 0.7 3.4 7.6 0.1 3.2 2 1 0 3 3 3 2 Protein of unknown function (DUF2808) DUF5050 PF16472.5 PVD29439.1 - 0.065 12.5 0.5 0.29 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) PrcB_C PF14343.6 PVD29439.1 - 0.096 12.8 5.3 7.1 6.8 0.8 4.0 3 1 0 3 3 3 0 PrcB C-terminal DUF4283 PF14111.6 PVD29440.1 - 3.8e-07 29.7 0.0 0.0039 16.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4283) NID PF07292.13 PVD29440.1 - 9.5e-05 23.0 3.8 7.7 7.2 0.1 5.3 4 1 0 4 4 4 1 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 PVD29440.1 - 0.0048 16.7 0.2 0.036 13.9 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4923 PF16270.5 PVD29440.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Barwin PF00967.17 PVD29441.1 - 0.037 13.9 0.2 0.045 13.6 0.2 1.1 1 0 0 1 1 1 0 Barwin family CaM_bdg_C0 PF10562.9 PVD29444.1 - 1.8 8.7 6.1 0.24 11.5 1.9 1.7 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF1308 PF07000.11 PVD29447.1 - 2.8e-62 209.5 0.1 5.1e-62 208.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) I-set PF07679.16 PVD29447.1 - 8.1e-44 147.6 0.0 3.9e-14 52.5 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD29447.1 - 3.5e-41 139.7 0.1 2e-13 50.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain DUF5614 PF18474.1 PVD29447.1 - 2e-35 122.1 0.1 5.2e-35 120.8 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5614) ig PF00047.25 PVD29447.1 - 2.6e-27 94.8 0.1 9.3e-09 35.3 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD29447.1 - 4.5e-24 84.6 0.1 2.1e-09 37.6 0.0 4.4 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD29447.1 - 4.4e-18 65.4 2.2 6.1e-06 26.4 0.0 5.0 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD29447.1 - 3.1e-09 36.3 0.0 0.0058 16.2 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 PVD29447.1 - 2.9e-05 24.1 2.3 0.0028 17.7 0.0 3.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 PVD29447.1 - 0.022 13.5 0.4 2.1 7.0 0.2 2.8 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 PVD29447.1 - 0.07 13.2 0.1 6.1 7.0 0.0 3.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain CoaE PF01121.20 PVD29448.1 - 6.1e-32 110.7 0.0 1.1e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 PVD29448.1 - 2.1e-09 37.7 0.2 3.3e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase-like AAA_18 PF13238.6 PVD29448.1 - 0.041 14.4 0.0 0.09 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain HCMV_UL124 PF17609.2 PVD29448.1 - 0.21 11.8 0.8 0.43 10.8 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function cNMP_binding PF00027.29 PVD29449.1 - 3.3e-14 52.7 0.4 1.7e-12 47.2 0.1 2.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Rrp15p PF07890.12 PVD29449.1 - 7.5 6.9 8.0 0.74 10.1 2.2 2.2 2 0 0 2 2 2 0 Rrp15p MMR_HSR1 PF01926.23 PVD29450.1 - 2.4e-47 159.7 0.0 8.8e-23 80.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP1_OBG PF01018.22 PVD29450.1 - 8.8e-30 103.3 25.2 6.3e-16 58.3 10.0 3.6 2 2 0 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 PVD29450.1 - 3.8e-21 75.3 0.5 4e-09 36.2 0.0 3.1 4 0 0 4 4 3 2 Ferrous iron transport protein B ABC_tran PF00005.27 PVD29450.1 - 1e-05 26.1 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter cobW PF02492.19 PVD29450.1 - 1.8e-05 24.4 0.1 2 8.0 0.0 4.1 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 PVD29450.1 - 0.00015 21.9 7.1 1.5 8.9 0.8 5.2 3 2 0 4 4 4 2 Dynamin family DUF2813 PF11398.8 PVD29450.1 - 0.0074 15.6 0.0 9.1 5.4 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) MeaB PF03308.16 PVD29450.1 - 0.011 14.7 0.6 19 4.1 0.0 3.8 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 PVD29450.1 - 0.011 16.2 0.0 11 6.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF1397 PF07165.11 PVD29450.1 - 0.028 13.9 5.2 11 5.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1397) RILP PF11461.8 PVD29450.1 - 0.033 14.4 0.6 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Rab interacting lysosomal protein AAA_21 PF13304.6 PVD29450.1 - 0.09 12.6 0.1 15 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1203 PF06718.11 PVD29450.1 - 0.1 12.9 0.0 21 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) DALR_1 PF05746.15 PVD29450.1 - 0.1 12.8 1.0 10 6.3 0.1 2.4 2 0 0 2 2 2 0 DALR anticodon binding domain MMR_HSR1_Xtn PF16897.5 PVD29450.1 - 0.14 12.2 0.5 7.1 6.7 0.1 2.8 2 2 0 2 2 2 0 C-terminal region of MMR_HSR1 domain NOG1 PF06858.14 PVD29450.1 - 0.15 11.9 0.6 16 5.4 0.1 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) DUF3479 PF11965.8 PVD29450.1 - 0.15 12.1 0.3 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) NusA_N PF08529.11 PVD29450.1 - 0.22 11.9 0.8 5 7.5 0.1 2.4 2 0 0 2 2 2 0 NusA N-terminal domain AAA_15 PF13175.6 PVD29450.1 - 4.5 6.9 6.6 19 4.8 0.4 2.8 2 2 0 2 2 2 0 AAA ATPase domain Amidohydro_2 PF04909.14 PVD29451.1 - 4.2e-64 217.1 0.1 4.7e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase SH3BP5 PF05276.14 PVD29452.1 - 9e-74 248.2 22.1 1.3e-73 247.7 22.1 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) UvsY PF11056.8 PVD29452.1 - 0.51 10.7 4.7 5.6 7.3 0.5 2.3 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Syntaxin-6_N PF09177.11 PVD29452.1 - 1.2 9.7 10.7 13 6.4 2.7 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SRCR PF00530.18 PVD29453.1 - 1.4e-33 115.4 6.9 1.8e-17 63.7 1.2 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD29453.1 - 3.7e-11 43.4 2.7 3.1e-05 24.4 0.8 2.9 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD29453.1 - 5.4e-05 23.7 0.5 0.027 15.0 0.0 2.9 3 0 0 3 3 3 2 Hepsin, SRCR domain GAS PF13851.6 PVD29453.1 - 0.00096 18.6 0.9 0.0034 16.8 0.4 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding YecR PF13992.6 PVD29453.1 - 0.005 17.1 0.6 3.6 8.0 0.0 2.4 2 0 0 2 2 2 2 YecR-like lipoprotein Prominin PF05478.11 PVD29453.1 - 0.035 12.1 0.6 0.083 10.8 0.6 1.6 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 PVD29453.1 - 0.17 11.9 3.7 1.2 9.2 0.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 PVD29453.1 - 4.4 7.1 8.7 17 5.2 0.1 3.3 2 1 0 3 3 3 0 PIN like domain Ldh_2 PF02615.14 PVD29455.1 - 4e-98 328.7 1.0 1e-53 182.6 0.0 2.0 1 1 1 2 2 2 2 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 PVD29456.1 - 1.3e-75 254.7 0.2 1.3e-48 165.8 0.0 2.0 1 1 1 2 2 2 2 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 PVD29457.1 - 1.6e-11 43.9 0.1 1.8e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Phi-29_GP16_7 PF06720.11 PVD29459.1 - 0.058 13.2 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DNA_pol_viral_N PF00242.17 PVD29459.1 - 0.066 12.7 0.3 0.065 12.7 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Fucokinase PF07959.12 PVD29459.1 - 0.078 11.9 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Ldh_2 PF02615.14 PVD29460.1 - 1.3e-98 330.2 4.4 6.4e-88 295.1 0.8 2.0 1 1 1 2 2 2 2 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 PVD29461.1 - 5.2e-94 315.1 0.1 6.1e-94 314.9 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF4213 PF13938.6 PVD29461.1 - 0.41 10.9 1.5 1.3 9.3 1.5 1.9 1 1 0 1 1 1 0 Putative heavy-metal chelation Ldh_2 PF02615.14 PVD29462.1 - 0.00014 21.2 0.4 0.00018 20.8 0.4 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 PVD29463.1 - 1.7e-116 389.1 0.0 2e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Peptidase_C2 PF00648.21 PVD29464.1 - 3.2e-41 141.3 0.1 7.2e-40 136.9 0.0 2.2 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 PVD29464.1 - 5.4e-13 48.8 7.8 8.4e-10 38.6 1.5 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 PVD29464.1 - 1.5e-09 38.2 0.1 3.3e-06 27.4 0.0 3.0 2 1 0 2 2 2 2 Calpain large subunit, domain III TPR_1 PF00515.28 PVD29464.1 - 0.0092 15.8 5.2 1.7 8.6 0.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD29464.1 - 0.043 14.1 2.3 1.2 9.4 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD29464.1 - 0.06 13.5 5.3 1.4 9.2 0.1 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat 7tm_2 PF00002.24 PVD29465.1 - 1.6e-29 103.0 12.7 1.6e-29 103.0 12.7 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD29465.1 - 1.8e-10 41.0 2.8 3.6e-10 40.0 2.8 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF5360 PF17314.2 PVD29465.1 - 0.25 11.4 8.7 0.73 9.9 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5360) LRR_8 PF13855.6 PVD29466.1 - 3.9e-20 71.4 0.0 2.2e-09 37.0 0.0 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 PVD29466.1 - 5.2e-09 36.2 0.2 9.7e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) TILa PF12714.7 PVD29466.1 - 0.035 14.0 0.7 0.078 12.9 0.7 1.5 1 0 0 1 1 1 0 TILa domain dsrm PF00035.26 PVD29467.1 - 1.8e-39 134.3 2.8 1.6e-16 60.7 0.0 3.3 3 0 0 3 3 3 3 Double-stranded RNA binding motif Staufen_C PF16482.5 PVD29467.1 - 3.4e-14 52.9 0.4 4.6e-11 42.9 0.1 3.1 3 0 0 3 3 3 1 Staufen C-terminal domain DND1_DSRM PF14709.7 PVD29467.1 - 2.5e-10 40.5 7.7 0.0012 19.1 0.8 4.6 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.16 PVD29467.1 - 0.15 12.5 3.6 2.3 8.6 0.4 2.4 2 0 0 2 2 2 0 LPP20 lipoprotein SH3_5 PF08460.10 PVD29467.1 - 0.16 12.1 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain ABC_membrane PF00664.23 PVD29468.1 - 2.3e-39 135.7 12.3 3.3e-39 135.2 12.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD29468.1 - 3.9e-35 121.3 0.0 6.5e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MTABC_N PF16185.5 PVD29468.1 - 1.4e-05 24.7 0.9 1.4e-05 24.7 0.9 2.0 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_16 PF13191.6 PVD29468.1 - 0.0017 18.8 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PVD29468.1 - 0.0018 17.9 0.1 0.0059 16.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 PVD29468.1 - 0.006 16.9 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PVD29468.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 PVD29468.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 PVD29468.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 PVD29468.1 - 0.034 13.9 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PVD29468.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PVD29468.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 PVD29468.1 - 0.098 12.1 0.1 0.27 10.6 0.1 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD29468.1 - 0.13 12.3 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 PVD29468.1 - 0.13 12.6 0.1 1.1 9.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PVD29468.1 - 0.16 12.0 0.2 1.3 9.0 0.0 2.5 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPTA PF01239.22 PVD29469.1 - 2.1e-52 173.4 10.1 2.3e-12 46.2 0.3 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 PVD29469.1 - 0.015 16.1 0.4 1e+02 4.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat GBR2_CC PF18455.1 PVD29469.1 - 0.015 15.4 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain RAI16-like PF10257.9 PVD29470.1 - 3.5e-101 338.7 0.0 4.8e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein HEAT_2 PF13646.6 PVD29470.1 - 0.13 12.6 0.0 0.83 10.1 0.0 2.3 1 0 0 1 1 1 0 HEAT repeats 7tm_1 PF00001.21 PVD29474.1 - 3.7e-82 275.6 0.0 8e-82 274.5 0.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD29474.1 - 1.9e-06 27.9 2.1 0.00022 21.0 1.4 2.3 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD29474.1 - 6.4e-05 22.7 6.6 6.4e-05 22.7 6.6 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CLN3 PF02487.17 PVD29474.1 - 0.0019 17.3 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 2 CLN3 protein DUF3504 PF12012.8 PVD29476.1 - 7.3e-19 68.3 0.0 1.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) YfkD PF14167.6 PVD29476.1 - 0.2 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 YfkD-like protein DUF3446 PF11928.8 PVD29476.1 - 6.2 7.2 11.7 5.6 7.3 1.7 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain Tnp_zf-ribbon_2 PF13842.6 PVD29477.1 - 0.00012 22.8 6.4 0.00023 21.9 6.4 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon zinc_ribbon_10 PF10058.9 PVD29477.1 - 0.067 12.9 2.1 0.13 12.0 2.1 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4407 PF14362.6 PVD29478.1 - 1.2 8.5 4.5 2.1 7.6 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gly_acyl_tr_N PF06021.11 PVD29479.1 - 1e-08 35.6 0.0 2.8e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_1 PF00583.25 PVD29479.1 - 1.8e-05 24.9 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PVD29479.1 - 3.6e-05 23.7 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 PVD29479.1 - 0.0012 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 PVD29479.1 - 0.0013 18.9 0.0 0.0071 16.5 0.0 2.2 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.7 PVD29479.1 - 0.04 14.4 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD29480.1 - 1.5e-13 51.0 0.0 5.1e-11 42.8 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PVD29480.1 - 3.5e-12 46.6 0.0 1.2e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 PVD29480.1 - 3.3e-11 43.1 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD29480.1 - 3.2e-10 40.0 0.0 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PVD29480.1 - 0.00018 21.4 0.1 0.0011 18.9 0.1 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 PVD29480.1 - 0.028 14.6 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ORC6 PF05460.13 PVD29481.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SDA1 PF05285.12 PVD29482.1 - 0.11 11.9 35.7 0.24 10.8 35.7 1.5 1 0 0 1 1 1 0 SDA1 PrmC_N PF17827.1 PVD29482.1 - 0.87 10.2 6.5 0.09 13.4 0.6 2.4 2 0 0 2 2 2 0 PrmC N-terminal domain CDC45 PF02724.14 PVD29482.1 - 5.1 5.3 29.6 73 1.4 30.4 2.1 2 0 0 2 2 2 0 CDC45-like protein BUD22 PF09073.10 PVD29482.1 - 9.3 5.5 38.2 0.031 13.6 28.2 1.9 2 0 0 2 2 2 0 BUD22 Tim54 PF11711.8 PVD29482.1 - 9.5 4.9 13.1 23 3.6 13.1 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM193_C PF15914.5 PVD29483.1 - 2.2e-16 59.3 2.6 2.2e-16 59.3 2.6 1.9 2 0 0 2 2 2 1 FAM193 family C-terminal SRP-alpha_N PF04086.13 PVD29483.1 - 3.5 7.5 38.6 2.3 8.1 23.6 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal LRR_8 PF13855.6 PVD29484.1 - 5.8e-15 54.8 5.2 9.2e-13 47.8 3.6 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD29484.1 - 3.2e-09 36.9 10.7 2.8e-05 24.4 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD29484.1 - 0.014 15.9 15.4 0.67 10.7 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 PVD29484.1 - 0.045 13.3 0.4 0.12 11.9 0.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeat SieB PF14163.6 PVD29484.1 - 0.33 10.4 3.9 0.39 10.2 0.1 2.5 3 0 0 3 3 3 0 Super-infection exclusion protein B MRC1 PF09444.10 PVD29488.1 - 0.2 12.2 7.4 0.031 14.8 3.0 1.8 2 0 0 2 2 2 0 MRC1-like domain Hormone_5 PF00184.17 PVD29489.1 - 1.6e-24 86.5 27.6 1.6e-24 86.5 27.6 1.8 2 0 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Ank_5 PF13857.6 PVD29491.1 - 9.4e-111 360.4 37.4 8.2e-15 54.7 0.2 15.3 6 5 9 15 15 15 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD29491.1 - 1e-108 356.1 48.1 1.9e-16 60.4 0.2 11.4 3 3 8 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.30 PVD29491.1 - 2e-105 341.0 46.5 1.3e-07 31.8 0.2 19.3 20 0 0 20 20 19 15 Ankyrin repeat Ank_4 PF13637.6 PVD29491.1 - 3.6e-102 333.5 29.8 4.5e-12 46.2 0.0 16.0 6 5 10 16 16 16 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29491.1 - 5.5e-97 305.9 30.7 1.8e-06 27.8 0.0 19.5 20 0 0 20 20 19 15 Ankyrin repeat RRM_1 PF00076.22 PVD29491.1 - 8.6e-58 192.1 0.0 6.9e-21 73.9 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PARP PF00644.20 PVD29491.1 - 1.6e-25 89.9 0.9 1.7e-23 83.2 0.9 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 PVD29491.1 - 3.4e-13 49.5 0.3 8.2e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD29491.1 - 5.4e-13 49.2 0.5 1.2e-12 48.0 0.5 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_7 PF16367.5 PVD29491.1 - 8.3e-06 25.8 0.0 0.27 11.4 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD29491.1 - 0.00016 21.6 0.4 0.18 11.8 0.1 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PVD29491.1 - 0.00028 20.7 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 PVD29491.1 - 0.00055 20.2 2.4 1.9 8.7 0.1 3.9 4 0 0 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 PVD29491.1 - 0.00079 19.4 0.1 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif CitG PF01874.16 PVD29491.1 - 0.0056 16.4 0.4 2.2 7.8 0.1 2.9 2 0 0 2 2 2 1 ATP:dephospho-CoA triphosphoribosyl transferase DUF5567 PF17722.1 PVD29491.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5567) SLD5_C PF16922.5 PVD29492.1 - 1.1e-18 67.1 0.6 7.5e-18 64.5 0.0 2.2 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 PVD29492.1 - 7.8e-05 23.1 2.1 0.00017 22.0 1.6 1.8 1 1 1 2 2 2 1 GINS complex protein CBM_21 PF03370.13 PVD29494.1 - 1.6e-27 95.9 0.1 2.4e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 PVD29494.1 - 1.7e-11 44.5 0.1 3.9e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) 7tm_1 PF00001.21 PVD29496.1 - 1.7e-31 109.6 10.0 2.2e-31 109.2 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD29496.1 - 2.3e-06 27.4 5.3 4.1e-06 26.6 5.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD29496.1 - 9.5e-06 25.5 4.5 9.5e-06 25.5 4.5 1.9 1 1 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srv PF10323.9 PVD29496.1 - 1e-05 25.0 6.9 1.9e-05 24.2 6.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 PVD29497.1 - 9.8e-14 51.3 1.8 9.8e-14 51.3 1.8 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29497.1 - 1e-05 25.0 1.9 1.8e-05 24.3 1.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD29497.1 - 0.013 15.3 3.5 0.019 14.7 3.5 1.2 1 0 0 1 1 1 0 Olfactory receptor TMEM132D_C PF15706.5 PVD29497.1 - 0.044 13.6 0.5 0.14 12.0 0.2 2.0 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PLAC8 PF04749.17 PVD29497.1 - 0.59 11.2 4.2 1.4 9.9 4.2 1.6 1 1 0 1 1 1 0 PLAC8 family Pkinase PF00069.25 PVD29498.1 - 7e-25 87.9 0.0 3.6e-16 59.3 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29498.1 - 6.4e-11 42.0 0.0 8.4e-08 31.8 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Baculo_LEF5 PF04838.12 PVD29498.1 - 0.024 14.7 1.8 0.036 14.1 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 DUF2797 PF10977.8 PVD29499.1 - 0.011 15.6 1.2 0.014 15.3 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) PKD PF00801.20 PVD29502.1 - 1.2e-74 246.1 74.0 3.5e-10 39.6 1.4 17.5 18 0 0 18 18 18 12 PKD domain REJ PF02010.15 PVD29502.1 - 3.1e-74 250.4 1.9 3.1e-74 250.4 1.9 2.2 2 0 0 2 2 2 1 REJ domain PKD_channel PF08016.12 PVD29502.1 - 5e-24 84.8 0.0 2.3e-23 82.6 0.0 2.1 1 1 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 PVD29502.1 - 3.8e-18 66.2 0.0 9.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain GPS PF01825.21 PVD29502.1 - 5.6e-09 36.4 7.8 3.2e-08 34.0 7.8 2.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Y_Y_Y PF07495.13 PVD29502.1 - 2.1e-05 24.4 3.1 4.2 7.4 0.1 6.9 8 0 0 8 8 8 1 Y_Y_Y domain PKD_3 PF16820.5 PVD29502.1 - 0.055 13.2 5.4 56 3.6 0.0 5.7 6 0 0 6 6 6 0 PKD-like domain Ricin_B_lectin PF00652.22 PVD29504.1 - 3.3e-09 37.1 0.1 0.00026 21.2 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 PVD29504.1 - 6.4e-09 35.8 0.0 9.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 PVD29504.1 - 7.3e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Homeodomain PF00046.29 PVD29505.1 - 1.5e-22 79.1 6.4 2.3e-22 78.6 6.4 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 PVD29505.1 - 2e-08 33.8 2.4 3.8e-08 32.9 2.4 1.5 1 0 0 1 1 1 1 OAR domain Mito_fiss_reg PF05308.11 PVD29505.1 - 0.12 12.4 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Enkurin PF13864.6 PVD29506.1 - 1.7e-28 98.9 6.0 1.7e-28 98.9 6.0 1.9 2 0 0 2 2 2 1 Calmodulin-binding Ras_bdg_2 PF14847.6 PVD29506.1 - 0.025 14.9 0.2 0.047 14.0 0.2 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 RDM PF11002.8 PVD29507.1 - 0.045 13.8 0.5 0.086 12.9 0.5 1.4 1 0 0 1 1 1 0 RFPL defining motif (RDM) PDE4_UCR PF18100.1 PVD29507.1 - 0.5 11.0 4.0 15 6.2 1.4 3.2 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) PI3K_1B_p101 PF10486.9 PVD29508.1 - 0.013 13.3 0.1 0.018 12.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1415 PF07209.12 PVD29512.1 - 0.073 12.8 1.7 0.071 12.9 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) DASH_Duo1 PF08651.10 PVD29512.1 - 0.078 12.8 0.5 21 4.9 0.0 3.2 3 1 1 4 4 4 0 DASH complex subunit Duo1 DHO_dh PF01180.21 PVD29513.1 - 0.003 16.8 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase RbsD_FucU PF05025.13 PVD29514.1 - 1.4e-39 135.6 0.0 1.5e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Syntaxin-18_N PF10496.9 PVD29515.1 - 3.5e-19 68.8 1.1 3.5e-19 68.8 1.1 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 PVD29515.1 - 0.25 11.7 6.1 0.15 12.4 2.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NOA36 PF06524.12 PVD29516.1 - 0.00016 21.1 12.8 0.00019 20.8 12.8 1.2 1 0 0 1 1 1 1 NOA36 protein PPP4R2 PF09184.11 PVD29516.1 - 0.0032 17.1 4.7 0.0032 17.1 4.7 1.1 1 0 0 1 1 1 1 PPP4R2 TFB6 PF17110.5 PVD29516.1 - 0.031 14.0 1.2 0.039 13.7 1.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 PVD29516.1 - 0.038 13.9 6.0 0.044 13.6 6.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 PVD29516.1 - 0.082 11.2 7.6 0.091 11.0 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 PVD29516.1 - 0.1 12.6 6.8 0.13 12.3 6.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 PVD29516.1 - 0.1 12.3 15.8 0.14 11.8 15.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 PVD29516.1 - 0.16 11.6 5.2 0.28 10.8 5.2 1.4 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 PVD29516.1 - 0.2 11.1 9.3 0.22 10.9 9.3 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 PVD29516.1 - 0.28 9.7 8.2 0.34 9.4 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ANAPC15 PF15243.6 PVD29516.1 - 0.31 11.4 12.3 0.44 11.0 12.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.12 PVD29516.1 - 0.52 8.4 10.6 0.63 8.2 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family GCIP PF13324.6 PVD29516.1 - 0.71 9.4 6.9 0.97 9.0 6.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 PVD29516.1 - 0.79 8.8 24.9 1 8.4 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 PVD29516.1 - 0.89 7.6 5.5 0.99 7.4 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 PVD29516.1 - 1 7.4 20.1 1.3 7.0 20.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 PVD29516.1 - 2.7 7.2 9.6 3.2 7.0 9.6 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 PVD29516.1 - 3.7 6.4 5.9 4.1 6.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MADF_DNA_bdg PF10545.9 PVD29519.1 - 0.038 14.3 0.3 0.072 13.4 0.3 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF5527 PF17665.1 PVD29519.1 - 0.066 12.7 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) MMS19_N PF14500.6 PVD29520.1 - 1.8e-56 191.6 0.3 1.8e-56 191.6 0.3 3.8 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 PVD29520.1 - 2.8e-41 142.0 14.9 7.1e-41 140.7 9.0 3.2 1 1 0 2 2 2 1 RNAPII transcription regulator C-terminal FIBP PF05427.11 PVD29520.1 - 0.0032 16.8 1.3 0.0078 15.5 1.3 1.6 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Peptidase_C69 PF03577.15 PVD29521.1 - 1e-05 24.7 0.0 1.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 PVD29521.1 - 0.00046 20.0 0.0 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Macro PF01661.21 PVD29522.1 - 7.7e-73 242.1 0.2 1.2e-28 99.6 0.1 4.9 4 0 0 4 4 4 4 Macro domain PARP PF00644.20 PVD29522.1 - 2e-17 63.5 1.4 1.2e-16 60.9 1.1 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29522.1 - 2.6e-05 24.7 0.1 0.00011 22.7 0.1 2.2 1 0 0 1 1 1 1 WWE domain SLS PF14611.6 PVD29522.1 - 0.00045 20.1 1.9 0.35 10.7 0.2 2.7 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator UreE_N PF02814.15 PVD29522.1 - 0.065 12.8 1.3 51 3.6 0.1 3.6 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain KH_1 PF00013.29 PVD29522.1 - 0.23 11.3 0.7 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 KH domain PARP PF00644.20 PVD29523.1 - 1.3e-19 70.6 0.5 4.7e-13 49.2 0.3 2.3 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29523.1 - 0.0036 17.9 2.7 0.0058 17.2 0.1 2.6 3 0 0 3 3 3 1 WWE domain YqgF PF14639.6 PVD29523.1 - 0.0065 16.3 2.3 0.045 13.5 2.3 2.2 1 1 1 2 2 2 1 Holliday-junction resolvase-like of SPT6 YqaH PF17448.2 PVD29523.1 - 0.11 12.8 1.5 0.25 11.7 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized YqaH-like Macro PF01661.21 PVD29524.1 - 4.2e-44 149.4 9.1 1.9e-16 60.2 0.0 6.5 4 2 1 5 5 5 4 Macro domain Glyco_hydro_4 PF02056.16 PVD29524.1 - 0.03 13.9 0.1 3.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase EspB PF05802.11 PVD29524.1 - 0.035 14.1 0.2 9.6 6.1 0.0 3.1 1 1 2 3 3 3 0 Enterobacterial EspB protein NPV_P10 PF05531.12 PVD29525.1 - 0.018 15.5 2.0 0.084 13.4 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 PVD29525.1 - 0.025 15.0 0.3 0.042 14.2 0.3 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 PVD29525.1 - 0.025 14.8 1.6 0.038 14.2 1.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 PVD29525.1 - 0.049 13.7 1.3 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 PVD29525.1 - 0.065 13.3 0.2 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Taxilin PF09728.9 PVD29525.1 - 0.086 12.0 0.1 0.25 10.5 0.1 1.6 2 0 0 2 2 2 0 Myosin-like coiled-coil protein SlyX PF04102.12 PVD29525.1 - 0.49 11.1 2.4 4.4 8.0 0.0 2.7 2 1 1 3 3 3 0 SlyX Snapin_Pallidin PF14712.6 PVD29525.1 - 0.67 10.4 2.8 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Macro PF01661.21 PVD29526.1 - 6.4e-83 274.6 5.9 5.9e-29 100.5 0.1 6.3 4 2 1 5 5 5 5 Macro domain PARP PF00644.20 PVD29526.1 - 3.1e-29 102.0 10.3 5.5e-21 75.1 5.1 4.0 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 PVD29526.1 - 0.00016 21.4 0.1 2 8.3 0.0 4.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWE PF02825.20 PVD29526.1 - 0.0039 17.8 0.3 0.014 15.9 0.3 2.1 1 0 0 1 1 1 1 WWE domain Macro PF01661.21 PVD29527.1 - 6e-65 216.6 6.5 1.2e-30 106.0 0.0 4.7 5 0 0 5 5 5 3 Macro domain PARP PF00644.20 PVD29527.1 - 1.2e-25 90.2 2.5 3.3e-25 88.8 2.5 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 PVD29527.1 - 0.049 13.5 0.1 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rdx PF10262.9 PVD29527.1 - 0.094 12.9 0.1 9.7 6.5 0.0 3.7 3 0 0 3 3 3 0 Rdx family PTS_2-RNA PF01885.16 PVD29527.1 - 0.095 12.7 2.4 1.1 9.3 0.1 3.2 3 0 0 3 3 3 0 RNA 2'-phosphotransferase, Tpt1 / KptA family KH_1 PF00013.29 PVD29527.1 - 0.32 10.8 2.2 1.8 8.5 0.2 3.3 3 0 0 3 3 3 0 KH domain Sun2_CC2 PF18580.1 PVD29527.1 - 1.3 9.3 6.8 26 5.1 0.3 4.6 4 0 0 4 4 4 0 SUN2 coiled coil domain 2 SLS PF14611.6 PVD29527.1 - 1.8 8.3 11.3 0.98 9.2 2.5 3.7 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Macro PF01661.21 PVD29528.1 - 3.4e-39 133.5 6.9 4.2e-13 49.4 0.1 4.6 3 1 0 3 3 3 3 Macro domain PARP PF00644.20 PVD29528.1 - 2.6e-16 59.8 0.5 5.8e-16 58.7 0.5 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29528.1 - 0.0091 16.6 0.0 0.047 14.3 0.0 2.3 1 0 0 1 1 1 1 WWE domain SLS PF14611.6 PVD29528.1 - 0.56 10.0 7.1 1.2 8.9 0.6 3.1 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator NID PF07292.13 PVD29529.1 - 0.00016 22.2 1.2 22 5.8 0.0 5.4 5 0 0 5 5 5 3 Nmi/IFP 35 domain (NID) SLS PF14611.6 PVD29529.1 - 0.15 11.9 5.8 0.031 14.1 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator PARP PF00644.20 PVD29530.1 - 1.5e-22 80.2 4.3 3.1e-21 75.9 4.3 2.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD29530.1 - 5.4e-17 61.9 0.3 1e-13 51.3 0.1 2.8 2 0 0 2 2 2 2 Macro domain WWE PF02825.20 PVD29530.1 - 0.00034 21.1 0.5 0.0026 18.3 0.1 2.7 3 0 0 3 3 3 1 WWE domain SLS PF14611.6 PVD29530.1 - 0.0032 17.3 3.1 1.3 8.8 0.0 3.2 2 1 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator RRM_1 PF00076.22 PVD29530.1 - 0.012 15.4 0.1 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4482 PF14818.6 PVD29531.1 - 0.0087 16.9 1.4 0.02 15.7 1.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4482) YabA PF06156.13 PVD29531.1 - 0.012 16.3 0.6 0.24 12.0 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 PVD29531.1 - 0.11 12.3 1.1 0.23 11.3 0.3 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 CENP-Q PF13094.6 PVD29531.1 - 0.13 12.4 0.5 0.22 11.7 0.5 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SKA1 PF07160.12 PVD29532.1 - 0.0019 18.1 11.8 0.046 13.6 8.0 2.1 1 1 0 2 2 2 2 Spindle and kinetochore-associated protein 1 YjcZ PF13990.6 PVD29532.1 - 0.072 12.5 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 YjcZ-like protein Baculo_PEP_C PF04513.12 PVD29532.1 - 0.075 13.1 3.8 0.21 11.6 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRI3BP PF14965.6 PVD29532.1 - 0.09 12.3 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Syntaxin-6_N PF09177.11 PVD29532.1 - 0.091 13.3 4.3 1.2 9.7 1.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Apolipoprotein PF01442.18 PVD29532.1 - 0.13 12.1 6.5 0.21 11.4 0.6 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain YabA PF06156.13 PVD29532.1 - 0.17 12.5 5.6 19 5.9 0.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 PVD29532.1 - 0.27 10.6 1.9 6.4 6.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 PVD29532.1 - 0.34 11.0 5.8 0.83 9.8 1.2 2.7 2 1 0 2 2 2 0 bZIP transcription factor 7tm_6 PF02949.20 PVD29532.1 - 0.38 9.8 1.2 0.51 9.4 0.6 1.5 1 1 0 1 1 1 0 7tm Odorant receptor TACC_C PF05010.14 PVD29532.1 - 1.3 8.8 13.7 2 8.2 10.3 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APG17 PF04108.12 PVD29532.1 - 1.7 7.7 10.5 9.5 5.2 0.2 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 NPV_P10 PF05531.12 PVD29532.1 - 1.8 9.1 7.4 8.7 6.9 0.3 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 PVD29532.1 - 2 8.8 5.7 10 6.5 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 PVD29532.1 - 6.6 6.3 9.5 4.4 6.8 0.3 2.7 3 0 0 3 3 3 0 fzo-like conserved region DUF4482 PF14818.6 PVD29533.1 - 0.035 15.0 2.7 0.089 13.7 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) YabA PF06156.13 PVD29533.1 - 0.05 14.2 1.2 0.73 10.5 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA CENP-Q PF13094.6 PVD29533.1 - 0.99 9.6 4.4 1.5 9.0 4.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit T6SS_VasJ PF16989.5 PVD29534.1 - 0.0014 18.2 0.1 0.0018 17.8 0.1 1.1 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ SlyX PF04102.12 PVD29535.1 - 0.062 13.9 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 PVD29536.1 - 0.0064 16.7 1.0 0.01 16.1 1.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 PVD29536.1 - 0.031 14.7 0.1 3.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 PVD29536.1 - 0.14 12.9 0.1 22 5.8 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin_2 PF01920.20 PVD29536.1 - 0.15 12.0 0.7 2.2 8.3 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit bZIP_2 PF07716.15 PVD29536.1 - 1.1 9.4 3.7 1.2 9.2 0.7 2.2 2 0 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 PVD29537.1 - 0.034 14.8 0.0 0.4 11.3 0.0 2.2 2 0 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.12 PVD29537.1 - 0.14 12.2 2.0 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 PVD29537.1 - 0.14 11.2 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 TraD_N PF12615.8 PVD29538.1 - 0.3 11.9 1.3 1.5 9.7 0.2 2.4 2 1 1 3 3 3 0 F sex factor protein N terminal PARP PF00644.20 PVD29539.1 - 7.2e-23 81.2 6.2 5.5e-21 75.0 6.2 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain NID PF07292.13 PVD29540.1 - 0.011 16.3 0.1 40 4.9 0.0 3.6 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Macro PF01661.21 PVD29541.1 - 2.1e-64 214.8 10.3 6e-33 113.4 0.1 4.0 4 0 0 4 4 4 3 Macro domain PARP PF00644.20 PVD29541.1 - 3.7e-25 88.7 4.3 1.6e-24 86.6 4.3 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD29541.1 - 0.00033 21.2 0.7 0.00033 21.2 0.7 2.7 3 0 0 3 3 3 1 WWE domain DUF4482 PF14818.6 PVD29542.1 - 0.0083 17.0 1.3 0.017 16.0 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4482) YabA PF06156.13 PVD29542.1 - 0.012 16.2 0.6 0.26 11.9 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CENP-Q PF13094.6 PVD29542.1 - 0.084 13.1 0.7 0.14 12.3 0.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SKA1 PF07160.12 PVD29542.1 - 0.16 11.8 1.3 0.33 10.8 0.7 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4050 PF13259.6 PVD29543.1 - 0.062 13.6 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Psu PF07455.11 PVD29543.1 - 0.098 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) YabA PF06156.13 PVD29543.1 - 0.18 12.5 2.5 8.3 7.1 1.1 2.2 2 0 0 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 PVD29544.1 - 2.7e-05 24.2 4.6 0.001 19.0 1.5 2.2 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF4201 PF13870.6 PVD29544.1 - 0.0055 16.5 3.6 0.14 11.9 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Phage_lysis PF03245.13 PVD29544.1 - 0.034 14.3 0.3 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Cob_adeno_trans PF01923.18 PVD29544.1 - 0.06 13.5 0.7 0.3 11.2 0.3 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Baculo_PEP_C PF04513.12 PVD29544.1 - 0.063 13.3 3.8 0.21 11.6 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 PVD29544.1 - 0.081 13.5 5.0 1 9.9 1.6 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlgN PF05130.12 PVD29544.1 - 0.12 12.9 3.4 0.72 10.4 0.9 2.2 2 0 0 2 2 2 0 FlgN protein Spc29 PF17082.5 PVD29544.1 - 0.13 12.1 0.9 0.74 9.6 0.4 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 Cauli_AT PF03233.13 PVD29544.1 - 0.15 12.0 3.7 0.58 10.1 2.0 2.2 2 0 0 2 2 2 0 Aphid transmission protein YjcZ PF13990.6 PVD29544.1 - 0.15 11.4 0.8 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 YjcZ-like protein DUF1157 PF06636.11 PVD29544.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) Fzo_mitofusin PF04799.13 PVD29544.1 - 0.18 11.3 4.8 4.4 6.8 0.3 2.4 2 0 0 2 2 2 0 fzo-like conserved region APG17 PF04108.12 PVD29544.1 - 0.24 10.5 7.6 3.3 6.7 3.0 2.0 1 1 0 2 2 2 0 Autophagy protein Apg17 YrzO PF14142.6 PVD29544.1 - 0.3 11.0 4.2 12 5.9 0.5 2.5 2 0 0 2 2 2 0 YrzO-like protein PCRF PF03462.18 PVD29544.1 - 0.33 10.8 3.0 1.5 8.7 2.3 1.9 2 0 0 2 2 2 0 PCRF domain bZIP_1 PF00170.21 PVD29544.1 - 0.38 10.9 4.2 1.9 8.6 0.5 2.6 2 1 0 2 2 2 0 bZIP transcription factor Apolipoprotein PF01442.18 PVD29544.1 - 0.73 9.7 10.6 0.21 11.4 0.6 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain YabA PF06156.13 PVD29544.1 - 0.74 10.5 7.6 19 5.9 0.0 2.7 2 1 0 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 PVD29544.1 - 0.91 9.3 8.2 3.9 7.3 4.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.20 PVD29544.1 - 0.92 9.5 10.5 9.5 6.2 7.2 2.6 2 1 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 PVD29544.1 - 1 9.6 7.4 2.3 8.4 1.9 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SSFA2_C PF14723.6 PVD29544.1 - 1.3 8.9 5.5 3.1 7.7 1.4 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Osmo_CC PF08946.10 PVD29544.1 - 1.4 9.2 7.1 1 9.7 4.3 2.2 2 2 0 2 2 2 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 PVD29544.1 - 1.6 9.2 7.9 8.7 6.9 0.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 PVD29544.1 - 1.7 9.4 4.6 4.9 7.9 1.9 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF948 PF06103.11 PVD29544.1 - 1.7 8.9 7.2 10 6.5 0.2 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 PVD29544.1 - 2.7 8.0 9.5 6 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) T6SS_VasJ PF16989.5 PVD29545.1 - 0.01 15.3 0.1 0.019 14.5 0.0 1.4 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ATG16 PF08614.11 PVD29547.1 - 0.011 16.0 0.3 0.017 15.4 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4988 PF16378.5 PVD29547.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function ZapB PF06005.12 PVD29547.1 - 0.039 14.4 0.0 3.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB LpxD PF04613.14 PVD29547.1 - 0.19 11.5 0.3 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD ABC_tran_CTD PF16326.5 PVD29547.1 - 0.26 11.5 1.1 9.7 6.5 0.3 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SKA2 PF16740.5 PVD29548.1 - 0.11 12.3 0.4 5.2 6.9 0.2 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 PVD29548.1 - 0.41 10.9 2.1 5.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MetallophosN PF16371.5 PVD29549.1 - 0.019 15.2 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase SlyX PF04102.12 PVD29549.1 - 0.044 14.4 0.0 1.2 9.8 0.0 2.2 2 0 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.12 PVD29549.1 - 0.056 13.5 0.8 0.57 10.2 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 PVD29549.1 - 0.14 11.2 0.0 10 5.1 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 CoA_binding PF02629.19 PVD29550.1 - 3.8e-32 110.8 0.4 3.8e-32 110.8 0.4 2.3 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 PVD29550.1 - 6.4e-22 78.0 0.1 1.1e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PVD29550.1 - 5.4e-08 32.7 0.1 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 PVD29550.1 - 1.8e-05 25.2 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ala_racemase_N PF01168.20 PVD29551.1 - 1.3e-21 77.2 0.0 1.7e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fumble PF03630.14 PVD29552.1 - 1.3e-118 396.0 0.1 2.8e-84 283.1 0.0 2.0 2 0 0 2 2 2 2 Fumble SpoU_methylase PF00588.19 PVD29552.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 SpoU rRNA Methylase family Ank_4 PF13637.6 PVD29553.1 - 1.8e-28 98.5 1.0 4.2e-08 33.6 0.0 6.0 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD29553.1 - 1.5e-23 83.1 0.0 6.3e-12 45.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD29553.1 - 3.7e-17 61.9 2.8 0.19 12.3 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 PVD29553.1 - 4e-17 62.1 0.5 4.3e-07 30.1 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29553.1 - 1.3e-15 56.0 2.4 0.032 14.8 0.0 7.1 6 1 0 6 6 6 5 Ankyrin repeat SOCS_box PF07525.16 PVD29553.1 - 7e-05 23.1 11.6 0.00013 22.2 11.6 1.5 1 0 0 1 1 1 1 SOCS box Glyoxalase_6 PF18029.1 PVD29553.1 - 0.043 14.6 0.1 1.8 9.4 0.1 2.6 2 1 0 2 2 2 0 Glyoxalase-like domain ATP-synt_ab PF00006.25 PVD29554.1 - 3.8e-67 226.1 0.0 5.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PVD29554.1 - 2.6e-13 50.3 0.1 6e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LRR_6 PF13516.6 PVD29555.1 - 0.031 14.3 6.7 5.3 7.4 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 PVD29555.1 - 4 8.4 10.3 19 6.3 0.6 5.5 4 2 0 4 4 4 0 Leucine Rich Repeat Glyco_transf_11 PF01531.16 PVD29556.1 - 1.2e-21 77.3 0.0 2.6e-18 66.3 0.1 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 11 DUF3011 PF11218.8 PVD29557.1 - 7.6e-09 35.8 0.0 2.4e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3011) Hamartin PF04388.12 PVD29557.1 - 4.3 5.9 16.3 5.1 5.6 16.3 1.1 1 0 0 1 1 1 0 Hamartin protein Organ_specific PF10950.8 PVD29557.1 - 4.3 8.1 6.4 11 6.7 6.3 1.7 1 1 0 1 1 1 0 Organ specific protein PH PF00169.29 PVD29558.1 - 1e-14 54.9 0.5 1.5e-14 54.3 0.5 1.3 1 0 0 1 1 1 1 PH domain Ig_3 PF13927.6 PVD29560.1 - 1.6e-08 35.0 0.0 3.5e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD29560.1 - 1.7e-08 34.4 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain IGFBP PF00219.18 PVD29560.1 - 4.3e-08 33.7 22.1 4.3e-08 33.7 22.1 2.0 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.15 PVD29560.1 - 7.8e-08 32.3 0.3 7.8e-08 32.3 0.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD29560.1 - 6.4e-06 26.1 1.4 6.4e-06 26.1 1.4 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain ig PF00047.25 PVD29560.1 - 0.00028 21.0 0.0 0.00049 20.2 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD29560.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain NHL PF01436.21 PVD29563.1 - 7.2e-28 95.2 9.0 2.1e-06 27.5 0.0 8.8 9 1 0 9 9 9 6 NHL repeat Thioredoxin_8 PF13905.6 PVD29563.1 - 1.3e-12 47.8 0.2 4.1e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 PVD29563.1 - 4.8e-06 26.4 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 PVD29563.1 - 0.0012 18.8 0.0 0.13 12.3 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin SGL PF08450.12 PVD29563.1 - 0.046 13.3 0.0 13 5.3 0.0 3.5 2 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PVD29563.1 - 0.08 13.2 0.0 19 5.5 0.0 3.6 5 0 0 5 5 5 0 Arylesterase Cupin_8 PF13621.6 PVD29564.1 - 3.6e-24 85.9 0.2 9.2e-24 84.5 0.2 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PVD29564.1 - 8.2e-11 42.3 0.1 8.2e-11 42.3 0.1 2.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 PVD29564.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Sod_Cu PF00080.20 PVD29565.1 - 1.7e-40 138.5 0.1 2.6e-12 47.1 0.1 6.3 6 0 0 6 6 6 6 Copper/zinc superoxide dismutase (SODC) I-set PF07679.16 PVD29566.1 - 4.1e-31 106.9 0.1 1.4e-17 63.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD29566.1 - 3.9e-27 94.7 3.3 4.4e-15 56.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD29566.1 - 2e-24 85.7 0.1 5e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD29566.1 - 6.7e-21 74.3 7.7 2e-13 50.3 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD29566.1 - 8.9e-13 48.4 1.4 0.0019 18.3 0.2 4.4 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD29566.1 - 4.6e-06 27.0 0.4 0.00048 20.5 0.1 2.6 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD29566.1 - 6.2e-06 26.2 0.0 0.092 12.8 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD29566.1 - 2e-05 24.7 0.1 0.00074 19.7 0.1 2.7 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Rhabdo_glycop PF00974.18 PVD29566.1 - 0.0013 17.3 1.8 0.0021 16.6 0.0 1.9 2 0 0 2 2 2 1 Rhabdovirus spike glycoprotein TMEM52 PF14979.6 PVD29566.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 Transmembrane 52 C2-set_2 PF08205.12 PVD29566.1 - 0.0034 17.4 12.9 0.0079 16.2 0.0 4.1 3 1 1 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD29566.1 - 0.0065 16.0 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set_CD47 PF08204.11 PVD29566.1 - 0.0075 16.2 0.9 0.38 10.7 0.2 2.7 1 1 1 2 2 2 1 CD47 immunoglobulin-like domain C1-set PF07654.15 PVD29566.1 - 0.032 14.6 0.3 3.8 7.9 0.1 3.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain DUF2749 PF10907.8 PVD29567.1 - 0.012 15.7 2.5 0.028 14.6 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) Kazal_1 PF00050.21 PVD29570.1 - 1.4e-15 57.0 21.2 7.2e-07 29.1 4.8 5.1 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PVD29570.1 - 9.7e-12 44.8 44.8 5.2e-07 29.7 4.1 6.3 5 1 0 5 5 5 3 Kazal-type serine protease inhibitor domain DnaJ PF00226.31 PVD29572.1 - 8.3e-29 99.5 2.6 1.2e-28 99.0 2.6 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 PVD29572.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein UBA_2 PF08587.11 PVD29572.1 - 0.18 12.0 1.3 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) CLP1_P PF16575.5 PVD29573.1 - 2.8e-57 193.5 0.0 4.9e-57 192.8 0.0 1.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 PVD29573.1 - 4.8e-33 114.1 0.3 7.9e-33 113.4 0.3 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 PVD29573.1 - 0.0038 17.3 0.1 0.038 14.1 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.23 PVD29573.1 - 0.0087 16.1 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CTV_P13 PF06922.11 PVD29573.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein ATP_bind_1 PF03029.17 PVD29573.1 - 0.057 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CLP1_N PF16573.5 PVD29573.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor Integrin_beta PF00362.18 PVD29574.1 - 3e-103 344.8 0.0 4.4e-103 344.3 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 PVD29574.1 - 1.3e-22 79.2 0.3 2.4e-22 78.3 0.3 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 PVD29574.1 - 1.5e-19 70.3 10.7 1.5e-19 70.3 10.7 3.4 3 0 0 3 3 3 1 Integrin beta tail domain I-EGF_1 PF18372.1 PVD29574.1 - 5.4e-10 39.2 6.1 5.4e-10 39.2 6.1 5.7 6 0 0 6 6 6 3 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 PVD29574.1 - 1e-08 34.8 7.9 1e-08 34.8 7.9 3.7 3 0 0 3 3 3 1 Integrin plexin domain EGF_2 PF07974.13 PVD29574.1 - 1.8e-06 28.2 35.7 3.8e-05 24.0 9.6 5.4 4 1 0 4 4 4 3 EGF-like domain Integrin_beta PF00362.18 PVD29575.1 - 1e-59 202.2 0.1 3.9e-42 144.6 0.0 2.3 1 1 1 2 2 2 2 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 PVD29575.1 - 6.8e-19 68.1 9.0 6.8e-19 68.1 9.0 4.5 4 2 0 4 4 4 1 Integrin beta tail domain Integrin_b_cyt PF08725.11 PVD29575.1 - 8.5e-14 51.0 0.8 1.8e-13 50.0 0.8 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 PVD29575.1 - 1.5e-10 40.9 5.0 1.5e-10 40.9 5.0 6.4 6 0 0 6 6 6 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 PVD29575.1 - 5.8e-07 29.8 52.8 6.1e-05 23.3 14.1 6.8 7 1 1 8 8 8 4 EGF-like domain Viral_Beta_CD PF04530.12 PVD29575.1 - 2.9 8.2 0.0 2.9 8.2 0.0 3.7 4 0 0 4 4 4 0 Viral Beta C/D like family Integrin_beta PF00362.18 PVD29577.1 - 2.6e-72 243.5 0.1 2.3e-59 201.0 0.0 2.1 1 1 1 2 2 2 2 Integrin beta chain VWA domain I-EGF_1 PF18372.1 PVD29577.1 - 8.3e-09 35.4 5.2 8.3e-09 35.4 5.2 3.2 3 0 0 3 3 3 1 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 PVD29577.1 - 1.2e-08 34.6 11.7 5.4e-08 32.5 11.7 2.2 1 0 0 1 1 1 1 Integrin plexin domain VWA PF00092.28 PVD29577.1 - 0.0002 21.6 0.0 0.0029 17.9 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain EGF_2 PF07974.13 PVD29577.1 - 0.0085 16.4 6.5 0.0085 16.4 6.5 3.8 4 0 0 4 4 4 1 EGF-like domain EGF_2 PF07974.13 PVD29578.1 - 4.1e-09 36.6 38.5 2.7e-07 30.8 13.1 4.2 4 0 0 4 4 4 2 EGF-like domain Integrin_b_cyt PF08725.11 PVD29578.1 - 0.00015 21.4 0.2 0.00023 20.8 0.2 1.2 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 PVD29578.1 - 0.0048 17.0 9.5 0.0048 17.0 9.5 3.7 4 0 0 4 4 4 2 Integrin beta epidermal growth factor like domain 1 Peptidase_C14 PF00656.22 PVD29579.1 - 1.7e-41 142.8 0.0 2.2e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain WH2 PF02205.20 PVD29580.1 - 3.2e-11 42.7 0.5 8.3e-11 41.4 0.5 1.8 1 0 0 1 1 1 1 WH2 motif Mem_trans PF03547.18 PVD29581.1 - 7.9e-17 60.7 3.3 3.1e-16 58.7 0.5 2.9 3 1 0 3 3 3 1 Membrane transport protein DEP PF00610.21 PVD29581.1 - 1.4e-16 60.3 0.2 2.7e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2868 PF11067.8 PVD29581.1 - 2.9e-05 23.8 0.5 0.06 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2868) SIT PF15330.6 PVD29581.1 - 0.97 9.9 0.0 0.97 9.9 0.0 2.7 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RhoGAP PF00620.27 PVD29582.1 - 1.6e-47 161.1 0.1 1.6e-47 161.1 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH_9 PF15410.6 PVD29582.1 - 2.5e-14 53.7 0.1 7.2e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ_6 PF17820.1 PVD29582.1 - 1.2e-10 41.1 0.0 2.8e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 PVD29582.1 - 1.4e-10 41.6 0.2 3.7e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 PVD29582.1 - 3.8e-07 30.4 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD29582.1 - 0.00037 20.8 0.1 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain DUF1708 PF08101.11 PVD29582.1 - 0.0074 15.5 0.2 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) PH_11 PF15413.6 PVD29582.1 - 0.028 14.9 0.1 0.23 11.9 0.1 2.7 1 0 0 1 1 1 0 Pleckstrin homology domain Nramp PF01566.18 PVD29584.1 - 2.6e-110 368.8 5.8 4e-110 368.2 5.8 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Nramp PF01566.18 PVD29585.1 - 5.3e-44 150.6 0.1 5.3e-44 150.6 0.1 2.2 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein WD40 PF00400.32 PVD29585.1 - 9.4e-05 23.1 15.5 0.93 10.5 0.0 7.2 8 0 0 8 8 8 2 WD domain, G-beta repeat DUF1992 PF09350.10 PVD29586.1 - 4.1e-23 81.3 0.0 8.7e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 PVD29587.1 - 8.5e-12 45.0 0.1 1.2e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 PVD29587.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 A repeated domain in UCH-protein Pkinase PF00069.25 PVD29588.1 - 4.1e-26 91.9 0.0 7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29588.1 - 1.1e-07 31.4 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD29588.1 - 0.0028 17.1 1.3 0.0028 17.1 1.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PVD29589.1 - 5.6e-23 81.6 0.0 9.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29589.1 - 8.1e-05 22.0 0.0 0.00022 20.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD29589.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD29589.1 - 0.00096 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD29589.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_10 PF00852.19 PVD29590.1 - 2e-38 131.9 0.0 2e-38 131.9 0.0 2.8 3 1 0 3 3 3 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD29590.1 - 2.9e-20 72.8 0.0 1.1e-19 70.9 0.0 2.1 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal zf-H2C2_2 PF13465.6 PVD29590.1 - 2.8e-19 68.6 27.3 1.1e-05 25.6 2.9 6.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD29590.1 - 3.7e-12 46.0 41.7 0.011 16.2 1.1 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29590.1 - 1.2e-08 35.0 44.4 0.0063 17.3 2.7 6.6 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD29590.1 - 0.00042 20.2 1.4 0.00042 20.2 1.4 6.4 6 1 0 6 6 6 2 C2H2-type zinc finger zf-Di19 PF05605.12 PVD29590.1 - 0.018 15.3 13.5 0.28 11.5 2.2 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PVD29590.1 - 0.067 13.5 32.5 0.36 11.2 0.5 5.4 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD29590.1 - 0.079 13.4 0.6 0.079 13.4 0.6 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type CpXC PF14353.6 PVD29590.1 - 0.43 10.6 11.7 1.4 9.0 0.9 4.1 1 1 2 3 3 3 0 CpXC protein Ribosomal_L31 PF01197.18 PVD29590.1 - 0.56 10.5 5.3 12 6.2 0.0 3.6 1 1 1 3 3 3 0 Ribosomal protein L31 zf_UBZ PF18439.1 PVD29590.1 - 1.4 8.6 14.2 21 4.8 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 PVD29590.1 - 4.7 7.5 22.3 8.7 6.6 1.3 5.7 4 1 1 5 5 5 0 AN1-like Zinc finger zf-C2H2 PF00096.26 PVD29591.1 - 4.4e-10 39.5 14.6 0.00029 21.1 0.1 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29591.1 - 8.3e-10 38.7 11.6 0.00015 22.3 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 PVD29591.1 - 9.5e-07 29.0 4.8 0.013 15.8 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD29591.1 - 1.9e-05 24.6 6.4 0.0073 16.3 0.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD29591.1 - 0.0002 21.7 15.5 0.012 16.0 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 PVD29591.1 - 0.0029 17.9 6.6 0.06 13.7 0.5 2.7 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 PVD29591.1 - 0.004 17.4 1.9 0.0054 17.0 1.9 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 PVD29591.1 - 0.0049 17.3 5.6 0.0055 17.1 0.2 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 PVD29591.1 - 0.013 16.2 3.2 0.046 14.4 0.3 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 PVD29591.1 - 0.022 14.4 1.2 2.8 7.7 0.0 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 PVD29591.1 - 0.036 14.4 6.0 0.53 10.6 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 PVD29591.1 - 0.054 12.7 1.2 0.49 9.5 1.2 1.9 1 1 0 1 1 1 0 Putative actin-like family DUF629 PF04780.12 PVD29591.1 - 0.23 9.9 1.3 6 5.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Elf1 PF05129.13 PVD29591.1 - 0.29 11.2 5.5 7.2 6.7 0.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like FYVE PF01363.21 PVD29591.1 - 3.1 8.0 10.7 0.11 12.6 3.1 2.1 1 1 1 2 2 2 0 FYVE zinc finger LSM PF01423.22 PVD29592.1 - 5.2e-16 58.1 0.3 8e-16 57.5 0.3 1.3 1 0 0 1 1 1 1 LSM domain AhpC-TSA PF00578.21 PVD29593.1 - 1.4e-39 134.8 0.0 1.8e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PVD29593.1 - 2e-16 60.0 0.0 2.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 PVD29593.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC 7tm_1 PF00001.21 PVD29594.1 - 1.3e-06 28.0 12.0 1.3e-06 28.0 12.0 2.5 1 1 2 3 3 3 1 7 transmembrane receptor (rhodopsin family) Lsr2 PF11774.8 PVD29594.1 - 0.17 12.1 1.3 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Lsr2 Kelch_1 PF01344.25 PVD29595.1 - 1.2e-49 165.6 14.9 1.8e-14 53.0 0.0 5.5 4 1 1 5 5 5 5 Kelch motif BTB PF00651.31 PVD29595.1 - 6.3e-27 94.0 0.4 1.2e-26 93.1 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD29595.1 - 2.3e-24 85.4 0.7 2.3e-24 85.4 0.7 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 PVD29595.1 - 1.8e-20 72.5 11.4 2.7e-08 33.8 0.0 5.3 2 1 3 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PVD29595.1 - 3.7e-14 52.0 7.6 7.3e-06 25.7 0.0 5.4 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PVD29595.1 - 2e-12 46.9 9.3 4.4e-06 26.6 0.0 4.8 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD29595.1 - 8e-10 38.8 2.6 0.00026 21.2 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD29595.1 - 1.4e-08 34.5 7.4 0.31 11.1 0.0 5.4 4 1 1 5 5 5 3 Kelch motif DUF3342 PF11822.8 PVD29595.1 - 0.00072 19.7 0.6 0.0025 18.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) dNK PF01712.19 PVD29596.1 - 2.4e-20 73.3 0.0 4.3e-20 72.5 0.0 1.4 1 1 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 PVD29596.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 Thymidylate kinase Peptidase_M19 PF01244.21 PVD29597.1 - 8.4e-113 376.7 0.0 9.9e-113 376.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_23 PF13489.6 PVD29598.1 - 2.8e-18 66.3 0.0 4.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD29598.1 - 7.4e-17 61.9 0.0 2.1e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD29598.1 - 3e-15 56.7 0.0 6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD29598.1 - 7.6e-14 52.1 0.0 1.5e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD29598.1 - 6.6e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD29598.1 - 1.8e-08 34.0 0.0 3.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PVD29598.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 PVD29598.1 - 0.0028 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 PVD29598.1 - 0.041 13.5 0.0 0.087 12.4 0.0 1.5 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 PVD29598.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.6 PVD29598.1 - 0.17 12.9 0.0 0.43 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PDCD2_C PF04194.13 PVD29599.1 - 1.4e-46 158.7 9.5 3.5e-44 151.0 3.2 2.7 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 PVD29599.1 - 2.4e-07 30.7 16.4 2.4e-07 30.7 16.4 3.1 3 0 0 3 3 3 1 MYND finger DUF4773 PF15998.5 PVD29601.1 - 4.8e-18 65.8 3.8 7.6e-18 65.2 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Tetraspanin PF00335.20 PVD29602.1 - 5.9e-24 85.0 6.3 9.4e-24 84.4 4.9 1.9 2 0 0 2 2 2 1 Tetraspanin family DUF2157 PF09925.9 PVD29602.1 - 0.00024 20.9 0.0 0.027 14.3 0.0 2.4 1 1 1 2 2 2 1 Predicted membrane protein (DUF2157) Abhydrolase_9_N PF15420.6 PVD29602.1 - 0.0098 15.9 2.1 2.6 8.0 0.0 3.5 3 1 0 3 3 3 1 Alpha/beta-hydrolase family N-terminus DUF2207 PF09972.9 PVD29602.1 - 0.052 12.3 0.3 0.071 11.9 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5345 PF17280.2 PVD29602.1 - 0.69 9.9 0.0 0.69 9.9 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF4307 PF14155.6 PVD29602.1 - 1.1 9.1 4.0 7 6.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF4131 PF13567.6 PVD29602.1 - 2.9 7.5 6.1 57 3.3 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF872 PF05915.12 PVD29602.1 - 9.2 6.5 6.3 5.8 7.1 0.1 2.5 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Phage_holin_3_6 PF07332.11 PVD29602.1 - 9.2 6.3 12.6 0.21 11.6 3.1 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SMC_N PF02463.19 PVD29603.1 - 1.5e-49 168.5 39.7 3.5e-48 163.9 39.7 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PVD29603.1 - 1.7e-21 76.7 0.0 5.2e-21 75.1 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PVD29603.1 - 1.5e-12 48.0 16.9 1.6e-06 28.2 0.4 3.9 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PVD29603.1 - 4.4e-07 30.0 74.4 0.00043 20.1 44.6 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 PVD29603.1 - 1.2e-05 25.9 60.4 1.2e-05 25.9 60.4 7.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 PVD29603.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 PVD29603.1 - 0.0069 16.4 2.5 0.29 11.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Ferritin PF00210.24 PVD29604.1 - 4e-27 94.9 0.8 4e-26 91.6 0.8 2.0 1 1 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 PVD29604.1 - 0.0016 18.9 0.3 0.0027 18.1 0.3 1.4 1 0 0 1 1 1 1 Rubrerythrin Codanin-1_C PF15296.6 PVD29604.1 - 0.16 12.0 0.7 0.49 10.5 0.1 2.0 3 0 0 3 3 3 0 Codanin-1 C-terminus Ferritin PF00210.24 PVD29605.1 - 1.8e-18 66.8 1.5 2.1e-08 34.2 0.4 2.1 2 0 0 2 2 2 2 Ferritin-like domain zf-C4 PF00105.18 PVD29606.1 - 6.3e-23 81.0 13.0 1.1e-22 80.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29606.1 - 5.1e-05 22.9 0.4 9.8e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor GRAB PF10375.9 PVD29606.1 - 0.0055 16.5 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain zf-RRPl_C4 PF17026.5 PVD29606.1 - 0.061 13.4 5.8 0.12 12.5 5.8 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type ATP-synt_E_2 PF08112.11 PVD29606.1 - 0.088 13.1 0.6 0.31 11.3 0.6 1.9 1 1 0 1 1 1 0 ATP synthase epsilon subunit zf-RING_2 PF13639.6 PVD29606.1 - 0.64 10.4 7.2 13 6.2 7.2 2.4 1 1 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 PVD29606.1 - 2.1 8.3 9.1 0.16 11.8 3.7 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sec8_exocyst PF04048.14 PVD29607.1 - 6.3e-17 61.8 1.8 3.4e-16 59.4 1.8 2.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 PVD29607.1 - 3.6e-05 23.2 6.2 0.00014 21.3 6.2 2.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 PVD29607.1 - 0.00018 20.2 15.4 0.00031 19.4 8.0 2.9 2 1 1 3 3 3 2 Centromere/kinetochore Zw10 DUF2451 PF10474.9 PVD29607.1 - 0.0023 17.7 1.8 0.019 14.8 0.0 3.4 4 1 0 4 4 4 1 Protein of unknown function C-terminus (DUF2451) DASH_Duo1 PF08651.10 PVD29607.1 - 0.0064 16.2 0.3 0.0064 16.2 0.3 3.5 3 0 0 3 3 3 1 DASH complex subunit Duo1 DUF1515 PF07439.11 PVD29607.1 - 0.038 14.0 1.2 0.53 10.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Dor1 PF04124.12 PVD29607.1 - 0.64 8.7 16.6 0.01 14.6 6.6 2.9 3 0 0 3 3 3 0 Dor1-like family KxDL PF10241.9 PVD29607.1 - 1 9.6 6.2 28 5.1 2.1 3.5 2 0 0 2 2 2 0 Uncharacterized conserved protein COG2 PF06148.11 PVD29607.1 - 3.7 7.6 6.8 18 5.4 1.4 4.4 4 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 PVD29607.1 - 5.6 7.7 6.0 17 6.1 0.2 4.1 4 0 0 4 4 4 0 SlyX Fib_alpha PF08702.10 PVD29607.1 - 5.9 7.1 7.9 6.6 6.9 1.2 4.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family EF-hand_6 PF13405.6 PVD29608.1 - 0.00056 19.6 1.4 0.0011 18.7 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PVD29608.1 - 0.003 17.4 0.0 0.02 14.7 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD29608.1 - 0.0063 16.0 0.4 0.0063 16.0 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PVD29608.1 - 0.0082 15.6 0.7 0.0082 15.6 0.7 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD29608.1 - 0.014 15.8 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair zf-RING_UBOX PF13445.6 PVD29609.1 - 1.5e-06 28.1 9.0 3.8e-06 26.8 9.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD29609.1 - 3.1e-05 23.7 10.0 6.5e-05 22.7 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD29609.1 - 0.00014 21.7 10.8 0.00027 20.7 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD29609.1 - 0.0048 17.0 10.4 0.011 15.8 10.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD29609.1 - 0.048 13.5 8.0 0.09 12.7 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD29609.1 - 0.076 13.4 10.8 0.19 12.1 10.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PVD29609.1 - 0.092 12.7 9.9 0.21 11.6 9.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain NHL PF01436.21 PVD29610.1 - 1.2e-07 31.4 0.3 0.25 11.4 0.0 4.7 4 0 0 4 4 4 2 NHL repeat DUF3583 PF12126.8 PVD29610.1 - 0.0001 21.9 3.6 0.00016 21.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.24 PVD29610.1 - 0.00011 22.3 9.3 0.00011 22.3 9.3 2.0 2 0 0 2 2 2 1 B-box zinc finger SGL PF08450.12 PVD29610.1 - 0.018 14.6 0.0 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SbcD_C PF12320.8 PVD29610.1 - 0.15 12.3 1.4 0.28 11.5 0.9 1.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Spond_N PF06468.13 PVD29611.1 - 4.7e-62 209.5 0.1 7e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 PVD29611.1 - 9.3e-11 41.8 6.8 9.3e-11 41.8 6.8 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Glyco_hydro_18 PF00704.28 PVD29612.1 - 2.3e-141 471.1 0.0 1.4e-69 235.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Sigma70_r1_2 PF00140.20 PVD29612.1 - 0.024 14.7 0.3 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 5_nucleotid PF05761.14 PVD29613.1 - 2.6e-132 442.0 0.0 3.9e-132 441.4 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase family Glyco_hydro_18 PF00704.28 PVD29613.1 - 1.4e-85 287.8 0.0 2.2e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 PVD29614.1 - 9.6e-20 70.8 33.9 1.5e-16 60.3 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PWWP PF00855.17 PVD29615.1 - 1.9e-10 41.0 0.0 7.1e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 PWWP domain WD40 PF00400.32 PVD29616.1 - 3e-21 75.3 3.4 1.7e-06 28.6 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD29616.1 - 5.8e-07 29.7 0.0 4.2 7.7 0.0 4.5 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain 7tm_1 PF00001.21 PVD29617.1 - 7.3e-31 107.5 3.8 9.8e-31 107.0 3.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29617.1 - 8.8e-07 28.6 3.6 1.4e-06 27.9 3.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD29617.1 - 2.6e-06 27.4 1.8 3.8e-06 26.9 1.8 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD29617.1 - 1.1e-05 25.2 5.9 1.7e-05 24.6 5.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD29618.1 - 1.2e-15 57.6 0.4 1.8e-15 57.0 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Transcrip_reg PF01709.20 PVD29619.1 - 2.5e-53 181.0 0.4 2.8e-53 180.8 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator zf-C4 PF00105.18 PVD29620.1 - 4.2e-21 75.2 12.1 7.5e-21 74.4 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29620.1 - 4.7e-10 39.4 1.5 1.8e-09 37.5 1.5 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 PVD29620.1 - 0.0018 18.4 5.3 0.0042 17.2 5.3 1.6 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF2318 PF10080.9 PVD29620.1 - 0.0066 16.5 0.9 0.013 15.6 0.9 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) TraY PF05509.11 PVD29620.1 - 0.038 14.0 0.2 0.085 12.9 0.2 1.5 1 0 0 1 1 1 0 TraY domain Prok-RING_1 PF14446.6 PVD29620.1 - 0.36 10.8 6.0 0.042 13.8 1.6 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C4 PF00105.18 PVD29621.1 - 2.3e-20 72.8 14.4 2.3e-20 72.8 14.4 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29621.1 - 8e-07 28.8 0.7 1.6e-06 27.9 0.7 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 PVD29621.1 - 0.019 15.1 7.3 0.028 14.5 5.5 2.2 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 PVD29621.1 - 0.027 14.4 2.6 0.027 14.4 2.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ATP-synt_E_2 PF08112.11 PVD29621.1 - 0.13 12.5 0.8 6.2 7.2 0.2 2.4 1 1 1 2 2 2 0 ATP synthase epsilon subunit Parvo_NS1 PF01057.17 PVD29621.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 zf-C4 PF00105.18 PVD29622.1 - 2.2e-22 79.3 14.3 6.1e-22 77.9 14.3 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29622.1 - 3.2e-06 26.9 3.9 6.1e-05 22.7 0.0 2.6 3 0 0 3 3 3 2 Ligand-binding domain of nuclear hormone receptor MotB_plug PF13677.6 PVD29622.1 - 0.068 12.8 0.3 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB zf-RRPl_C4 PF17026.5 PVD29622.1 - 3.8 7.6 12.2 5.6 7.1 10.1 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type LIM_bind PF01803.16 PVD29623.1 - 2.2e-55 187.8 0.9 6e-42 143.8 0.1 2.5 1 1 1 2 2 2 2 LIM-domain binding protein zf-C4 PF00105.18 PVD29623.1 - 6.7e-22 77.7 12.9 1.6e-21 76.6 12.9 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) LID PF17916.1 PVD29623.1 - 3.7e-17 61.7 2.2 7.2e-17 60.7 2.2 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) Hormone_recep PF00104.30 PVD29623.1 - 1.1e-05 25.2 1.0 2.4e-05 24.0 0.0 2.0 3 0 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 PVD29623.1 - 0.034 14.3 4.7 0.065 13.3 4.7 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2318 PF10080.9 PVD29623.1 - 0.079 13.1 4.3 0.16 12.1 4.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PCI PF01399.27 PVD29624.1 - 5.3e-13 49.4 0.2 5.3e-13 49.4 0.2 2.7 3 1 0 3 3 3 1 PCI domain DUF4903 PF16246.5 PVD29624.1 - 3.7 7.2 6.9 0.24 11.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4903) AAA_10 PF12846.7 PVD29625.1 - 0.071 12.0 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Herpes_BTRF1 PF04682.12 PVD29625.1 - 0.076 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region ATP-synt_ab PF00006.25 PVD29626.1 - 1.9e-61 207.5 0.0 2.6e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PVD29626.1 - 5.2e-22 78.1 0.4 1.1e-21 77.0 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 PVD29626.1 - 0.0042 16.3 0.4 0.0074 15.5 0.1 1.5 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 PVD29626.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 PVD29626.1 - 0.02 15.3 0.0 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PVD29626.1 - 0.033 14.1 0.1 0.075 12.9 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 PVD29626.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 PVD29626.1 - 0.12 12.7 0.9 0.31 11.4 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD29626.1 - 0.18 12.2 0.1 0.69 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PVD29626.1 - 0.18 12.3 0.1 0.49 10.9 0.1 1.7 1 0 0 1 1 1 0 ABC transporter DnaJ PF00226.31 PVD29627.1 - 4e-15 55.7 0.8 1.7e-14 53.7 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 PVD29627.1 - 5.2e-15 55.0 0.0 2.1e-14 53.1 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 PVD29627.1 - 2.5e-12 45.9 2.2 5.2e-05 23.0 1.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD29627.1 - 9.5e-11 41.1 2.3 0.00027 20.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD29627.1 - 6.5e-10 38.4 0.9 0.002 18.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat RRM_occluded PF16842.5 PVD29627.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif TPR_12 PF13424.6 PVD29627.1 - 3.1e-06 27.4 0.2 8.8e-06 25.9 0.2 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD29627.1 - 0.00014 22.4 0.2 0.00043 20.9 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 PVD29627.1 - 0.00083 19.6 0.2 0.00083 19.6 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger containing family TPR_17 PF13431.6 PVD29627.1 - 0.0012 19.1 0.4 2.5 8.7 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD29627.1 - 0.0054 16.6 0.7 2.8 7.9 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD29627.1 - 0.0083 16.1 0.9 2.2 8.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD29627.1 - 0.021 14.5 0.6 1.6 8.5 0.5 3.1 2 1 1 3 3 3 0 TPR repeat TPR_19 PF14559.6 PVD29627.1 - 0.021 15.3 1.3 0.063 13.8 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_5 PF13893.6 PVD29627.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PVD29627.1 - 0.035 14.2 6.5 0.077 13.1 6.5 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 PVD29627.1 - 0.056 13.4 2.2 0.11 12.4 2.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SPEG_u2 PF16650.5 PVD29627.1 - 0.059 13.6 0.3 1.8 8.8 0.3 3.0 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein ANAPC3 PF12895.7 PVD29627.1 - 0.069 13.4 0.3 0.35 11.1 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PVD29627.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD29627.1 - 0.084 13.7 0.6 10 7.2 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat CENP-C_mid PF15620.6 PVD29627.1 - 0.11 12.5 32.0 0.24 11.3 32.0 1.5 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region zf-CCCH_4 PF18044.1 PVD29627.1 - 0.27 11.1 5.4 0.52 10.2 5.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger TPR_6 PF13174.6 PVD29627.1 - 0.51 11.1 2.0 11 6.9 0.7 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5009 PF16401.5 PVD29628.1 - 1.3e-06 28.1 5.7 1e-05 25.1 5.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) DUF2537 PF10801.8 PVD29628.1 - 0.02 15.1 0.2 0.02 15.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) COX7a PF02238.15 PVD29628.1 - 0.3 11.5 3.9 2.7 8.5 0.1 3.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DUF3021 PF11457.8 PVD29628.1 - 7.1 7.0 20.7 0.44 10.9 3.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Laminin_G_2 PF02210.24 PVD29629.1 - 7e-09 36.3 0.0 9.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 PVD29629.1 - 2.9e-05 24.3 0.0 0.00015 22.0 0.0 2.0 1 1 0 1 1 1 1 Laminin G domain Jnk-SapK_ap_N PF09744.9 PVD29630.1 - 2.3 8.4 9.4 0.19 11.9 3.6 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Shugoshin_C PF07557.11 PVD29631.1 - 2.3e-10 40.1 4.2 2.3e-10 40.1 4.2 2.8 2 0 0 2 2 2 1 Shugoshin C terminus Glyco_hydro_3_C PF01915.22 PVD29631.1 - 0.0041 17.1 0.1 0.017 15.0 0.1 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MICSWaP PF17018.5 PVD29631.1 - 0.041 13.4 0.6 0.14 11.7 0.4 1.9 2 0 0 2 2 2 0 Spore wall protein Nucleos_tra2_C PF07662.13 PVD29632.1 - 6.3e-76 254.8 3.6 6.3e-76 254.8 3.6 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD29632.1 - 4.7e-25 88.0 0.5 4.7e-25 88.0 0.5 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD29632.1 - 2.7e-07 30.8 4.8 2.7e-07 30.8 4.8 2.9 3 0 0 3 3 3 1 Nucleoside recognition Lectin_C PF00059.21 PVD29632.1 - 8.6e-07 29.7 1.3 1.5e-06 28.9 0.3 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ig_3 PF13927.6 PVD29633.1 - 6.7e-22 77.9 0.5 1.5e-09 38.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD29633.1 - 1.6e-21 76.1 0.0 2.7e-11 43.4 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD29633.1 - 3.6e-18 65.5 0.0 7.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD29633.1 - 8.4e-14 51.7 0.4 6.8e-07 29.5 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD29633.1 - 2.3e-06 27.6 0.1 0.042 13.9 0.1 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 PVD29633.1 - 0.00027 21.1 0.1 0.19 12.0 0.0 3.6 2 1 2 4 4 4 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 PVD29633.1 - 0.00045 20.4 5.8 0.054 13.7 0.1 3.4 2 1 0 3 3 3 2 Immunoglobulin V-set domain V-set_2 PF15910.5 PVD29633.1 - 0.033 14.3 0.1 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 ICOS V-set domain Adeno_E3_CR1 PF02440.15 PVD29633.1 - 0.061 13.1 0.2 1.3 8.9 0.1 2.5 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 PVD29633.1 - 0.076 12.6 0.1 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 PVD29633.1 - 0.12 12.4 0.1 15 5.7 0.1 2.9 2 1 1 3 3 3 0 Izumo-like Immunoglobulin domain I-set PF07679.16 PVD29634.1 - 2.7e-12 46.6 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD29634.1 - 1.6e-11 44.7 0.4 2e-11 44.3 0.4 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD29634.1 - 1.6e-08 34.8 0.2 2.1e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD29634.1 - 0.00018 21.6 0.8 0.00029 21.0 0.8 1.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 PVD29634.1 - 0.00033 21.0 0.0 0.00041 20.7 0.0 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 PVD29634.1 - 0.0018 18.3 0.3 0.005 16.9 0.3 1.8 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 PVD29634.1 - 0.002 18.3 0.3 0.003 17.7 0.3 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD29634.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.4 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 PVD29635.1 - 2.7e-07 31.1 0.0 4.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD29635.1 - 1.9e-05 24.7 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD29635.1 - 0.00026 21.1 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD29635.1 - 0.0037 17.3 0.0 0.0066 16.5 0.0 1.4 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 PVD29635.1 - 0.0076 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain SAG PF04092.13 PVD29635.1 - 0.11 13.3 0.0 0.45 11.3 0.0 1.8 1 1 0 1 1 1 0 SRS domain Peptidase_M16_M PF16187.5 PVD29637.1 - 1.6e-97 326.2 0.1 3.7e-97 325.0 0.1 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PVD29637.1 - 1.5e-40 138.6 0.0 2.9e-39 134.4 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PVD29637.1 - 3.1e-35 121.9 0.0 1.1e-18 67.9 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF1269 PF06897.12 PVD29638.1 - 0.023 15.0 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MccV PF17508.2 PVD29638.1 - 0.052 14.1 0.2 0.057 14.0 0.2 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin DUF1542 PF07564.11 PVD29638.1 - 0.077 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Gly-zipper_Omp PF13488.6 PVD29638.1 - 0.15 12.1 9.7 0.3 11.1 9.7 1.5 1 1 0 1 1 1 0 Glycine zipper Thioredoxin PF00085.20 PVD29641.1 - 1.1e-06 28.6 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 PVD29641.1 - 0.036 14.0 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 PVD29641.1 - 0.037 14.5 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain FA_desaturase PF00487.24 PVD29642.1 - 9.6e-24 84.6 23.0 1.5e-23 83.9 22.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 PVD29642.1 - 3.7e-15 55.1 0.6 3.7e-15 55.1 0.6 1.8 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) DUF2062 PF09835.9 PVD29642.1 - 0.037 13.9 0.5 0.072 12.9 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Caveolin PF01146.17 PVD29642.1 - 0.061 13.3 0.0 0.83 9.6 0.0 2.4 2 1 0 2 2 2 0 Caveolin Metallopep PF12044.8 PVD29642.1 - 0.073 11.7 1.9 0.1 11.2 1.9 1.1 1 0 0 1 1 1 0 Putative peptidase family eRF1_3 PF03465.15 PVD29643.1 - 3e-39 134.0 1.2 1.1e-38 132.2 0.2 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 PVD29643.1 - 2.1e-28 99.3 0.0 6.7e-17 62.1 0.0 2.4 1 1 1 2 2 2 2 eRF1 domain 2 eRF1_1 PF03463.15 PVD29643.1 - 3.6e-16 59.3 0.0 6.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.26 PVD29643.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Vac7 PF12751.7 PVD29643.1 - 0.47 9.9 2.0 16 4.8 0.1 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Acyltransferase PF01553.21 PVD29644.1 - 3.2e-11 43.0 0.0 9.3e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase CUE PF02845.16 PVD29644.1 - 2.1e-05 24.1 0.1 4.7e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 CUE domain zf-RRN7 PF11781.8 PVD29645.1 - 7.2e-05 22.4 1.1 7.2e-05 22.4 1.1 2.0 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 AbLIM_anchor PF16182.5 PVD29645.1 - 0.00099 19.0 2.8 0.00099 19.0 2.8 1.9 2 0 0 2 2 2 1 Putative adherens-junction anchoring region of AbLIM TPR_2 PF07719.17 PVD29646.1 - 2.8e-05 23.9 8.6 2.9 8.2 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD29646.1 - 0.00076 19.7 6.3 0.06 13.6 0.3 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PVD29646.1 - 0.012 15.9 13.0 5.4 7.4 0.1 6.2 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD29646.1 - 0.014 15.9 3.9 2.1 8.9 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD29646.1 - 1.1 9.3 5.1 4.8 7.2 0.3 3.4 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_8 PF13181.6 PVD29646.1 - 6.6 7.2 0.0 6.6 7.2 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD29647.1 - 0.00014 21.7 4.8 0.0079 16.2 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD29647.1 - 0.0063 16.8 1.6 1.3 9.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD29647.1 - 0.096 13.6 0.2 2.2 9.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD29647.1 - 0.14 12.5 11.5 0.23 11.8 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD29647.1 - 0.72 9.8 2.6 15 5.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD29647.1 - 7.7 6.5 9.7 4.9 7.1 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 PVD29648.1 - 7.1e-54 183.3 0.0 9.9e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 PVD29649.1 - 1.7e-14 53.4 0.8 4.2e-14 52.2 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD29649.1 - 8.7e-09 35.0 3.2 9.8e-08 31.7 1.1 3.3 3 0 0 3 3 3 1 F-box domain Zip PF02535.22 PVD29650.1 - 9.8e-57 192.6 1.2 1.1e-56 192.5 1.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Aldo_ket_red PF00248.21 PVD29651.1 - 8.9e-71 238.5 0.1 2.6e-46 158.1 0.0 4.3 2 2 1 3 3 3 3 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 PVD29651.1 - 0.0056 16.9 0.2 2.5 8.4 0.0 3.5 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain SOCS PF12610.8 PVD29651.1 - 0.0077 16.6 0.0 25 5.4 0.0 3.3 3 0 0 3 3 3 1 Suppressor of cytokine signalling DUF2293 PF10056.9 PVD29651.1 - 0.048 13.9 0.4 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) HTH_24 PF13412.6 PVD29651.1 - 0.083 12.5 0.5 57 3.4 0.0 4.2 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding RRM_4 PF10598.9 PVD29651.1 - 0.095 13.0 0.0 25 5.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 Aldo_ket_red PF00248.21 PVD29652.1 - 1.2e-28 100.2 0.0 1.5e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sulfotransfer_1 PF00685.27 PVD29653.1 - 5.9e-26 91.5 2.4 5e-14 52.4 0.1 4.0 2 2 1 3 3 3 3 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD29653.1 - 2.2e-19 70.7 7.9 3.4e-08 34.1 0.9 5.4 2 2 2 4 4 4 3 Sulfotransferase family Josephin PF02099.17 PVD29653.1 - 0.025 14.7 0.5 6.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Josephin SRPRB PF09439.10 PVD29653.1 - 0.13 11.7 0.0 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RNase_T PF00929.24 PVD29656.1 - 7.9e-15 55.8 0.1 1.5e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 Exonuclease SAP PF02037.27 PVD29656.1 - 0.068 13.0 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 SAP domain DUF4307 PF14155.6 PVD29657.1 - 0.016 15.0 0.1 0.044 13.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Prominin PF05478.11 PVD29659.1 - 7e-35 120.2 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Prominin Hemolysin_N PF12563.8 PVD29659.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 Hemolytic toxin N terminal Baculo_PEP_C PF04513.12 PVD29659.1 - 2.5 8.1 7.1 5.8 6.9 0.6 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4744 PF15918.5 PVD29660.1 - 2.3 9.1 11.3 6.4 7.7 2.6 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4744) Adhes-Ig_like PF09085.10 PVD29660.1 - 2.5 8.3 9.3 42 4.3 0.2 3.6 1 1 1 2 2 2 0 Adhesion molecule, immunoglobulin-like 7tm_1 PF00001.21 PVD29661.1 - 2.4e-60 204.1 2.3 3.3e-60 203.6 2.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29661.1 - 2.8e-09 36.7 1.5 3.8e-09 36.3 1.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD29661.1 - 2.8e-06 27.2 8.6 5.8e-06 26.1 8.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD29661.1 - 4.9e-06 26.5 1.7 4.9e-06 26.5 1.7 1.4 1 1 0 1 1 1 1 Olfactory receptor ABC2_membrane_2 PF12679.7 PVD29661.1 - 0.013 14.8 0.5 2.6 7.3 0.0 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 PVD29661.1 - 0.031 13.4 1.8 0.68 9.0 0.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein CitMHS PF03600.16 PVD29661.1 - 0.043 13.0 0.6 0.059 12.6 0.6 1.2 1 0 0 1 1 1 0 Citrate transporter 7TM_GPCR_Srbc PF10316.9 PVD29661.1 - 0.37 10.2 9.5 0.27 10.7 8.2 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 PVD29662.1 - 6.9e-21 74.7 0.0 6.9e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29662.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.9 PVD29662.1 - 0.0055 15.7 0.3 0.007 15.4 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt LRRFIP PF09738.9 PVD29663.1 - 8e-28 97.8 6.7 8e-28 97.8 6.7 4.5 3 2 1 4 4 4 1 LRRFIP family TPR_MLP1_2 PF07926.12 PVD29664.1 - 4.6e-06 26.7 18.5 9.9e-06 25.6 18.5 1.5 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 PVD29664.1 - 6.2e-05 21.8 12.1 7.4e-05 21.5 12.1 1.0 1 0 0 1 1 1 1 Macoilin family APG6_N PF17675.1 PVD29664.1 - 0.00011 22.7 18.5 0.00013 22.5 18.5 1.0 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 PVD29664.1 - 0.00082 18.8 15.7 0.0032 16.8 15.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 PVD29664.1 - 0.00087 19.5 16.0 0.0012 19.1 16.0 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 GAS PF13851.6 PVD29664.1 - 0.00097 18.5 15.2 0.0013 18.1 15.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 PVD29664.1 - 0.0011 19.5 5.8 0.0014 19.1 5.8 1.3 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF4200 PF13863.6 PVD29664.1 - 0.0014 19.0 18.2 0.0016 18.8 18.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 PVD29664.1 - 0.0018 17.2 14.7 0.0021 17.0 14.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein CC2-LZ PF16516.5 PVD29664.1 - 0.0037 17.6 12.6 0.0037 17.6 12.6 1.4 1 1 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Laminin_II PF06009.12 PVD29664.1 - 0.0037 17.3 9.0 0.0044 17.0 9.0 1.0 1 0 0 1 1 1 1 Laminin Domain II Phage_GP20 PF06810.11 PVD29664.1 - 0.0058 16.4 15.1 0.026 14.3 7.3 2.0 1 1 1 2 2 2 1 Phage minor structural protein GP20 DUF5082 PF16888.5 PVD29664.1 - 0.0078 16.5 9.5 0.018 15.3 8.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Prominin PF05478.11 PVD29664.1 - 0.0097 13.9 5.6 0.011 13.8 5.6 1.0 1 0 0 1 1 1 1 Prominin CCDC144C PF14915.6 PVD29664.1 - 0.0098 15.0 10.4 0.0098 15.0 10.4 1.9 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region FlxA PF14282.6 PVD29664.1 - 0.012 15.6 10.7 0.019 15.0 10.7 1.3 1 0 0 1 1 1 0 FlxA-like protein LPP PF04728.13 PVD29664.1 - 0.017 15.5 9.0 0.019 15.4 1.2 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 PVD29664.1 - 0.019 15.0 10.3 0.14 12.2 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 PVD29664.1 - 0.019 15.3 8.6 0.04 14.3 1.1 2.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 PVD29664.1 - 0.021 14.8 17.9 0.038 14.0 17.9 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOGA PF11365.8 PVD29664.1 - 0.025 15.7 12.8 0.072 14.2 11.6 1.9 1 1 1 2 2 2 0 Protein SOGA ERM PF00769.19 PVD29664.1 - 0.027 14.3 17.6 0.031 14.1 17.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4349 PF14257.6 PVD29664.1 - 0.027 13.9 11.4 0.037 13.5 11.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Spc24 PF08286.11 PVD29664.1 - 0.03 14.6 15.3 0.13 12.5 6.7 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 PVD29664.1 - 0.032 14.0 17.9 0.55 10.0 7.8 2.3 1 1 2 3 3 3 0 Septum formation initiator BRE1 PF08647.11 PVD29664.1 - 0.041 13.9 16.9 0.11 12.6 15.5 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 PVD29664.1 - 0.042 14.3 21.4 0.8 10.2 9.9 2.0 1 1 1 2 2 2 0 Cell division protein ZapB CALCOCO1 PF07888.11 PVD29664.1 - 0.043 12.7 14.6 0.043 12.7 14.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 PVD29664.1 - 0.044 13.9 16.9 0.14 12.3 1.3 2.9 2 1 1 3 3 3 0 bZIP transcription factor HemX PF04375.14 PVD29664.1 - 0.044 13.1 12.2 0.052 12.8 12.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GIT_CC PF16559.5 PVD29664.1 - 0.049 13.5 11.6 0.24 11.3 7.9 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 PVD29664.1 - 0.05 13.4 17.1 0.084 12.7 17.1 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HMMR_C PF15908.5 PVD29664.1 - 0.054 13.7 11.9 0.75 10.0 1.3 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal AAA_13 PF13166.6 PVD29664.1 - 0.055 12.1 9.6 0.054 12.1 9.6 1.0 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.6 PVD29664.1 - 0.055 13.9 15.3 0.26 11.8 14.6 1.9 1 1 0 1 1 1 0 Snapin/Pallidin IFT20 PF14931.6 PVD29664.1 - 0.056 13.6 12.2 0.08 13.1 12.2 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 YlqD PF11068.8 PVD29664.1 - 0.056 13.8 11.6 0.077 13.4 11.6 1.3 1 0 0 1 1 1 0 YlqD protein TMPIT PF07851.13 PVD29664.1 - 0.057 12.7 9.7 0.067 12.4 9.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 PVD29664.1 - 0.059 12.9 12.7 0.074 12.6 12.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 T3SSipB PF16535.5 PVD29664.1 - 0.06 13.8 7.6 0.067 13.7 7.6 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF4164 PF13747.6 PVD29664.1 - 0.061 13.6 14.2 0.1 12.9 14.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF745 PF05335.13 PVD29664.1 - 0.069 12.9 12.0 0.081 12.6 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 PVD29664.1 - 0.071 13.3 17.9 0.14 12.3 10.5 2.0 1 1 1 2 2 2 0 Tropomyosin like THOC7 PF05615.13 PVD29664.1 - 0.073 13.3 14.5 0.1 12.9 14.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 FlgN PF05130.12 PVD29664.1 - 0.075 13.5 11.3 0.093 13.2 11.3 1.1 1 0 0 1 1 1 0 FlgN protein DUF2968 PF11180.8 PVD29664.1 - 0.075 12.7 14.3 0.12 12.0 14.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) HALZ PF02183.18 PVD29664.1 - 0.077 13.2 18.3 0.68 10.2 0.9 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper Phlebovirus_NSM PF07246.11 PVD29664.1 - 0.088 12.2 8.7 0.12 11.7 8.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 PVD29664.1 - 0.09 13.1 15.4 0.099 13.0 15.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 PVD29664.1 - 0.092 13.5 6.7 0.12 13.1 6.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF5595 PF18077.1 PVD29664.1 - 0.093 12.8 12.8 0.78 9.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) LRRFIP PF09738.9 PVD29664.1 - 0.097 12.1 16.4 0.25 10.8 7.1 2.0 1 1 1 2 2 2 0 LRRFIP family Prefoldin_2 PF01920.20 PVD29664.1 - 0.11 12.5 17.1 1.4 8.9 4.8 2.3 1 1 1 2 2 2 0 Prefoldin subunit PV-1 PF06637.11 PVD29664.1 - 0.11 11.3 11.5 0.13 11.1 11.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) HIP1_clath_bdg PF16515.5 PVD29664.1 - 0.12 12.9 16.6 0.15 12.7 16.6 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 PVD29664.1 - 0.13 12.5 8.4 0.18 12.0 8.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 PVD29664.1 - 0.13 12.3 17.1 0.3 11.1 17.1 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 PVD29664.1 - 0.14 12.3 15.4 1.2 9.4 2.8 2.6 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II PCRF PF03462.18 PVD29664.1 - 0.15 12.0 9.0 0.14 12.0 9.0 1.0 1 0 0 1 1 1 0 PCRF domain DivIVA PF05103.13 PVD29664.1 - 0.17 12.0 14.2 6 7.0 14.2 2.1 1 1 0 1 1 1 0 DivIVA protein ApoO PF09769.9 PVD29664.1 - 0.17 11.8 2.8 0.21 11.6 2.8 1.2 1 0 0 1 1 1 0 Apolipoprotein O FH2 PF02181.23 PVD29664.1 - 0.17 11.0 9.3 0.2 10.7 9.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain TMF_TATA_bd PF12325.8 PVD29664.1 - 0.17 12.1 15.8 0.51 10.6 15.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.17 PVD29664.1 - 0.19 12.3 15.8 1.4 9.5 8.6 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor MCRS_N PF13325.6 PVD29664.1 - 0.19 11.7 9.7 0.23 11.5 9.7 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Borrelia_orfA PF02414.15 PVD29664.1 - 0.19 11.3 7.3 0.22 11.2 7.3 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF4407 PF14362.6 PVD29664.1 - 0.21 10.9 11.0 0.26 10.6 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Siah-Interact_N PF09032.11 PVD29664.1 - 0.22 11.9 15.0 6.6 7.1 14.7 2.1 1 1 1 2 2 2 0 Siah interacting protein, N terminal ATG16 PF08614.11 PVD29664.1 - 0.23 11.7 17.5 0.3 11.3 17.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) WXG100 PF06013.12 PVD29664.1 - 0.23 11.7 7.4 7.2 6.9 5.6 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 PVD29664.1 - 0.23 11.7 14.4 2.5 8.4 5.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nup88 PF10168.9 PVD29664.1 - 0.26 9.1 14.3 0.27 9.0 14.3 1.0 1 0 0 1 1 1 0 Nuclear pore component YabA PF06156.13 PVD29664.1 - 0.27 11.9 11.4 0.71 10.6 11.4 1.7 1 1 0 1 1 1 0 Initiation control protein YabA ISG65-75 PF11727.8 PVD29664.1 - 0.27 10.4 7.9 0.3 10.3 7.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein PRKG1_interact PF15898.5 PVD29664.1 - 0.28 12.1 16.0 0.89 10.5 7.7 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 PVD29664.1 - 0.32 10.8 12.3 0.41 10.5 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1204 PF06721.11 PVD29664.1 - 0.33 10.4 12.7 0.38 10.2 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Fzo_mitofusin PF04799.13 PVD29664.1 - 0.34 10.4 10.9 1.6 8.2 10.2 1.8 1 1 0 1 1 1 0 fzo-like conserved region HAUS6_N PF14661.6 PVD29664.1 - 0.34 10.5 12.4 0.4 10.2 12.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 PVD29664.1 - 0.34 9.4 10.9 0.38 9.3 10.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 PVD29664.1 - 0.35 11.6 11.0 0.58 10.9 11.0 1.4 1 1 0 1 1 1 0 Occludin homology domain SlyX PF04102.12 PVD29664.1 - 0.36 11.5 13.1 0.68 10.6 6.5 2.2 1 1 1 2 2 2 0 SlyX Sec20 PF03908.13 PVD29664.1 - 0.36 10.8 5.3 0.25 11.3 2.4 1.8 1 1 1 2 2 2 0 Sec20 Ax_dynein_light PF10211.9 PVD29664.1 - 0.38 10.7 17.3 3.4 7.6 16.2 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain Lipoprotein_20 PF13942.6 PVD29664.1 - 0.38 10.7 13.3 0.64 9.9 13.3 1.4 1 1 0 1 1 1 0 YfhG lipoprotein DUF4201 PF13870.6 PVD29664.1 - 0.39 10.4 17.4 6.8 6.4 16.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 PVD29664.1 - 0.4 11.1 17.3 0.71 10.2 17.3 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 PVD29664.1 - 0.4 11.2 6.7 29 5.2 6.7 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 PVD29664.1 - 0.41 10.1 16.1 1.1 8.7 16.1 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Spectrin PF00435.21 PVD29664.1 - 0.42 11.1 13.6 0.71 10.4 13.6 1.4 1 1 0 1 1 1 0 Spectrin repeat Dor1 PF04124.12 PVD29664.1 - 0.45 9.1 8.9 0.52 8.9 8.9 1.0 1 0 0 1 1 1 0 Dor1-like family V_ATPase_I PF01496.19 PVD29664.1 - 0.48 8.3 7.7 0.49 8.2 7.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dCache_2 PF08269.11 PVD29664.1 - 0.52 9.4 8.4 0.61 9.2 8.4 1.1 1 0 0 1 1 1 0 Cache domain Nup54 PF13874.6 PVD29664.1 - 0.52 10.4 12.9 0.78 9.8 12.0 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF812 PF05667.11 PVD29664.1 - 0.56 9.0 14.3 0.68 8.7 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cluap1 PF10234.9 PVD29664.1 - 0.61 9.4 14.6 1.4 8.2 13.4 1.7 1 1 1 2 2 2 0 Clusterin-associated protein-1 Rho_Binding PF08912.11 PVD29664.1 - 0.61 10.9 17.6 0.97 10.3 7.8 2.1 1 1 1 2 2 2 0 Rho Binding XhlA PF10779.9 PVD29664.1 - 0.64 10.3 11.1 11 6.3 10.1 2.5 1 1 0 1 1 1 0 Haemolysin XhlA Sec2p PF06428.11 PVD29664.1 - 0.65 10.0 16.7 4.3 7.4 16.7 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Fmp27_WPPW PF10359.9 PVD29664.1 - 0.76 8.6 10.6 0.83 8.4 10.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tweety PF04906.13 PVD29664.1 - 0.77 8.4 2.7 0.87 8.2 2.7 1.1 1 0 0 1 1 1 0 Tweety FUSC PF04632.12 PVD29664.1 - 0.79 8.2 4.7 0.79 8.2 4.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 PVD29664.1 - 0.84 9.2 8.7 1.1 8.8 8.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 PVD29664.1 - 0.97 8.9 9.6 1 8.8 9.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 PVD29664.1 - 1.1 9.8 15.3 3.2 8.3 9.2 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 PVD29664.1 - 1.1 9.4 18.1 4.9 7.2 18.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1451 PF07295.11 PVD29664.1 - 1.1 9.3 8.8 1.2 9.1 8.8 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF4337 PF14235.6 PVD29664.1 - 1.2 9.3 11.8 2.9 8.0 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) TMF_DNA_bd PF12329.8 PVD29664.1 - 1.2 9.2 19.2 0.7 9.9 15.7 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 PVD29664.1 - 1.3 9.0 14.3 5.7 6.9 1.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit Fungal_TACC PF12709.7 PVD29664.1 - 1.3 9.5 14.3 1.2 9.6 1.0 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins CCDC-167 PF15188.6 PVD29664.1 - 1.3 9.4 14.6 4.5 7.7 14.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 5_nucleotid PF05761.14 PVD29664.1 - 1.5 7.7 7.9 1.5 7.6 7.9 1.1 1 0 0 1 1 1 0 5' nucleotidase family GrpE PF01025.19 PVD29664.1 - 1.6 8.4 16.1 4.2 7.0 8.1 2.0 1 1 1 2 2 2 0 GrpE Swi5 PF07061.11 PVD29664.1 - 1.7 8.8 13.4 5.3 7.2 6.4 2.1 1 1 1 2 2 2 0 Swi5 Cnn_1N PF07989.11 PVD29664.1 - 1.8 8.8 16.4 6 7.1 1.6 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CASP_C PF08172.12 PVD29664.1 - 1.8 7.8 14.5 4.1 6.7 7.8 2.0 1 1 1 2 2 2 0 CASP C terminal DUF948 PF06103.11 PVD29664.1 - 2.1 8.7 4.9 47 4.3 4.9 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TEX13 PF15186.6 PVD29664.1 - 2.5 7.8 12.1 3.2 7.4 12.1 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Nas2_N PF18265.1 PVD29664.1 - 2.8 7.9 10.7 6.2 6.8 4.3 2.2 1 1 1 2 2 2 0 Nas2 N_terminal domain Tho2 PF11262.8 PVD29664.1 - 3.1 6.9 10.9 3.4 6.8 10.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KfrA_N PF11740.8 PVD29664.1 - 3.1 8.5 15.9 49 4.7 15.9 2.0 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF16 PF01519.16 PVD29664.1 - 3.1 8.3 11.5 12 6.4 11.5 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cauli_AT PF03233.13 PVD29664.1 - 3.3 7.6 10.5 3.1 7.7 3.5 2.0 1 1 1 2 2 2 0 Aphid transmission protein BST2 PF16716.5 PVD29664.1 - 3.7 8.2 17.3 24 5.6 8.7 2.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF4446 PF14584.6 PVD29664.1 - 3.9 7.5 9.4 30 4.6 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) FemAB PF02388.16 PVD29664.1 - 4 6.2 10.4 4.4 6.1 10.4 1.1 1 0 0 1 1 1 0 FemAB family Atg14 PF10186.9 PVD29664.1 - 4 6.4 14.9 4.7 6.2 14.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mei5 PF10376.9 PVD29664.1 - 4.4 7.1 17.0 6 6.7 9.7 2.1 1 1 1 2 2 2 0 Double-strand recombination repair protein DUF1043 PF06295.12 PVD29664.1 - 4.8 7.2 12.5 3.5 7.7 9.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4391 PF14335.6 PVD29664.1 - 5.2 6.7 13.9 13 5.4 4.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) BBS2_C PF14782.6 PVD29664.1 - 5.4 5.7 15.4 1.8 7.2 1.4 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Med30 PF11315.8 PVD29664.1 - 5.8 7.1 12.9 8.3 6.6 5.5 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 LMBR1 PF04791.16 PVD29664.1 - 5.9 5.7 7.3 7.1 5.4 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cep57_CLD_2 PF14197.6 PVD29664.1 - 6 7.0 19.0 9.5 6.4 1.5 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CorA PF01544.18 PVD29664.1 - 6.1 6.1 7.8 13 5.0 7.8 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-H PF05837.12 PVD29664.1 - 6.4 7.2 16.6 4.4 7.7 7.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) E2F_CC-MB PF16421.5 PVD29664.1 - 8.9 6.8 11.7 9 6.7 5.6 2.1 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain DUF3847 PF12958.7 PVD29664.1 - 9.6 6.4 18.7 2.6 8.2 11.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Aldo_ket_red PF00248.21 PVD29665.1 - 1.9e-41 142.2 0.0 3.8e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cytochrom_B561 PF03188.16 PVD29666.1 - 7.4e-40 136.3 9.9 7.4e-40 136.3 9.9 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 PVD29666.1 - 0.00028 20.9 0.2 0.00028 20.9 0.2 2.9 1 1 2 3 3 3 1 Tight junction protein, Claudin-like RIFIN PF02009.16 PVD29666.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Rifin DUF4293 PF14126.6 PVD29666.1 - 1.9 8.7 9.1 3.6 7.8 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4293) Hol_Tox PF16935.5 PVD29666.1 - 3.2 7.9 5.1 4.3 7.5 0.4 2.6 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Ost4 PF10215.9 PVD29666.1 - 4.4 7.2 9.2 5.4 6.9 1.5 2.8 2 0 0 2 2 2 0 Oligosaccaryltransferase RCC1 PF00415.18 PVD29670.1 - 4.9e-35 119.9 9.2 7e-12 45.8 0.7 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD29670.1 - 2e-15 56.1 20.2 1.6e-06 27.7 3.8 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 PVD29670.1 - 0.028 14.3 0.0 6.4 6.7 0.1 2.7 2 1 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain VWA_2 PF13519.6 PVD29671.1 - 3.3e-21 75.9 0.9 1.5e-20 73.8 0.1 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 PVD29671.1 - 3.6e-09 35.9 5.3 0.00082 19.1 0.6 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif Ssl1 PF04056.14 PVD29671.1 - 1.2e-08 35.0 0.2 2e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 PVD29671.1 - 0.043 13.6 7.9 0.47 10.3 0.1 3.2 2 1 1 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif TPPII_N PF12583.8 PVD29671.1 - 0.12 13.0 0.4 0.12 13.0 0.4 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal PID PF00640.23 PVD29671.1 - 0.31 11.1 1.3 0.85 9.6 0.2 2.3 2 1 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) OB_NTP_bind PF07717.16 PVD29672.1 - 4.6e-26 91.0 0.0 1.6e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD29672.1 - 7.5e-07 29.5 0.2 2.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 PVD29672.1 - 0.0044 17.3 1.4 0.15 12.3 0.1 2.5 1 1 1 2 2 2 2 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD29673.1 - 2.6e-25 88.6 0.0 6.9e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD29673.1 - 6.6e-13 49.0 0.0 2e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 PVD29673.1 - 3.9e-11 43.1 0.1 9.5e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RSRP PF17069.5 PVD29673.1 - 0.65 9.5 44.5 1.4 8.5 44.5 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC53 PF10152.9 PVD29673.1 - 9.2 6.7 13.9 12 6.3 0.4 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MMR_HSR1 PF01926.23 PVD29674.1 - 1.7e-15 57.1 0.0 8.6e-14 51.6 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD29674.1 - 1e-07 31.6 0.5 3.7e-06 26.5 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD29674.1 - 1.8e-07 31.2 1.3 0.0014 18.5 0.0 2.7 2 1 1 3 3 3 2 RsgA GTPase AIG1 PF04548.16 PVD29674.1 - 4.4e-05 22.9 0.2 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Exo_endo_phos_2 PF14529.6 PVD29674.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Septin PF00735.18 PVD29674.1 - 0.0064 15.8 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Septin G-alpha PF00503.20 PVD29674.1 - 0.014 14.6 0.0 5.1 6.1 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 PVD29674.1 - 0.018 14.8 0.3 5.4 6.7 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 PVD29674.1 - 0.024 13.7 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 PVD29674.1 - 0.028 14.5 0.5 3.8 7.5 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA_24 PF13479.6 PVD29674.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD29674.1 - 0.1 13.2 0.0 0.29 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Integrin_alpha2 PF08441.12 PVD29675.1 - 6e-28 97.9 0.3 3.4e-11 42.7 0.0 3.4 1 1 2 3 3 3 3 Integrin alpha FG-GAP PF01839.23 PVD29675.1 - 8.9e-14 51.3 4.8 0.00017 21.7 0.1 3.7 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 PVD29675.1 - 1.6e-06 28.6 3.9 0.05 14.2 0.7 3.6 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 PVD29675.1 - 0.1 12.7 3.5 0.22 11.6 3.5 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Cadherin_C_2 PF16492.5 PVD29675.1 - 0.53 11.1 0.0 0.53 11.1 0.0 2.8 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal PRIMA1 PF16101.5 PVD29675.1 - 5.4 7.1 5.8 51 3.9 3.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 zf-C2H2 PF00096.26 PVD29676.1 - 7e-10 38.8 6.8 6.2e-05 23.2 0.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD29676.1 - 2.9e-06 26.9 0.6 2.9e-06 26.9 0.6 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD29676.1 - 0.00014 22.4 9.5 0.4 11.6 0.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger IRF-2BP1_2 PF11261.8 PVD29676.1 - 0.008 15.7 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger Luteo_Vpg PF01659.16 PVD29676.1 - 0.06 13.7 0.7 0.14 12.5 0.7 1.6 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein zf-H2C2_2 PF13465.6 PVD29676.1 - 0.13 12.7 0.8 0.13 12.7 0.8 3.9 4 0 0 4 4 4 0 Zinc-finger double domain DUF4958 PF16319.5 PVD29678.1 - 0.15 10.0 0.0 0.17 9.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) zf-C2H2 PF00096.26 PVD29679.1 - 2.2e-15 56.1 42.5 0.0042 17.5 2.0 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29679.1 - 6.2e-08 32.8 47.1 0.024 15.4 0.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger Elf1 PF05129.13 PVD29679.1 - 0.00027 20.9 0.3 0.00027 20.9 0.3 3.3 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like zf-Di19 PF05605.12 PVD29679.1 - 0.00054 20.2 21.6 0.0011 19.3 0.6 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 PVD29679.1 - 0.013 15.1 12.9 1.7 8.3 0.1 5.0 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger DUF4451 PF14616.6 PVD29679.1 - 0.014 15.6 1.9 0.014 15.6 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) DUF629 PF04780.12 PVD29679.1 - 0.047 12.2 4.2 0.64 8.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 PVD29679.1 - 0.065 13.0 34.9 0.2 11.4 0.7 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type TF_Zn_Ribbon PF08271.12 PVD29679.1 - 0.089 12.3 2.4 35 4.0 0.0 3.9 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2_6 PF13912.6 PVD29679.1 - 0.12 12.5 0.1 0.12 12.5 0.1 5.7 6 0 0 6 6 5 0 C2H2-type zinc finger Rubredoxin PF00301.20 PVD29679.1 - 0.25 11.4 6.9 25 5.0 0.7 4.3 3 1 0 3 3 3 0 Rubredoxin zf_C2H2_ZHX PF18387.1 PVD29679.1 - 0.28 10.9 8.5 4.6 7.0 0.2 3.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_2 PF13240.6 PVD29679.1 - 0.31 10.8 7.6 2.8 7.8 0.1 4.2 3 0 0 3 3 3 0 zinc-ribbon domain Ephrin_rec_like PF07699.13 PVD29679.1 - 0.43 10.4 0.1 0.43 10.4 0.1 6.3 6 0 0 6 6 6 0 Putative ephrin-receptor like FYVE_2 PF02318.16 PVD29679.1 - 0.43 10.8 19.1 1.9 8.7 1.0 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger zf-C2H2_2 PF12756.7 PVD29679.1 - 0.89 9.9 0.1 0.73 10.2 0.6 4.9 4 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PVD29679.1 - 1.2 9.6 23.7 0.31 11.5 0.4 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 PVD29679.1 - 2 9.2 21.3 4.3 8.2 1.1 3.4 3 0 0 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.5 PVD29679.1 - 2 8.9 8.6 5.7 7.5 0.0 3.4 4 0 0 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 PVD29680.1 - 9.8e-07 28.9 12.2 0.0039 17.6 1.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29680.1 - 0.00018 22.1 11.6 0.064 14.1 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 PVD29680.1 - 0.0087 16.2 6.1 0.36 11.0 0.8 2.5 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD29680.1 - 0.011 16.0 3.4 0.16 12.4 0.0 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 PVD29680.1 - 0.012 15.4 0.3 0.65 9.9 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease zf-LYAR PF08790.11 PVD29680.1 - 0.073 13.0 1.5 5.8 6.9 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-CCHC_2 PF13696.6 PVD29680.1 - 0.074 12.9 0.5 0.16 11.8 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF629 PF04780.12 PVD29680.1 - 0.088 11.3 3.5 1.8 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 PVD29680.1 - 0.097 12.3 0.4 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF4428 PF14471.6 PVD29680.1 - 0.098 12.6 0.1 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) PHM7_cyt PF14703.6 PVD29680.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter zf-Di19 PF05605.12 PVD29680.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD29680.1 - 2.2 8.1 11.6 0.07 12.9 4.4 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 PVD29680.1 - 3.5 8.2 11.5 13 6.5 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-AN1 PF01428.16 PVD29680.1 - 4.1 7.7 10.1 4.7 7.5 2.2 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2 PF00096.26 PVD29681.1 - 4e-08 33.3 14.5 0.00031 21.0 2.3 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29681.1 - 7.9e-06 26.3 13.6 0.0031 18.2 1.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 PVD29681.1 - 5.4e-05 22.9 2.8 0.012 15.4 0.3 2.6 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 PVD29681.1 - 0.0017 18.2 0.9 0.0017 18.2 0.9 3.5 3 0 0 3 3 3 1 zinc-finger of a C2HC-type DUF2256 PF10013.9 PVD29681.1 - 0.0062 16.6 3.6 0.5 10.5 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 PVD29681.1 - 0.019 15.0 4.1 2 8.5 0.4 2.3 1 1 1 2 2 2 0 CpXC protein zf-met PF12874.7 PVD29681.1 - 0.021 15.2 7.2 4.9 7.7 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD29681.1 - 0.049 13.9 6.2 1.7 9.0 0.5 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 PVD29681.1 - 0.063 13.5 5.6 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon HypA PF01155.19 PVD29681.1 - 0.068 13.2 0.7 0.096 12.7 0.7 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cript PF10235.9 PVD29681.1 - 0.079 13.5 1.1 0.88 10.2 0.1 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT FdhE PF04216.12 PVD29681.1 - 0.095 12.6 1.5 0.12 12.2 1.5 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation GcpE PF04551.14 PVD29681.1 - 0.13 11.3 1.0 1.8 7.6 0.1 2.0 1 1 1 2 2 2 0 GcpE protein Terminase_GpA PF05876.12 PVD29681.1 - 0.15 10.6 3.0 0.19 10.2 3.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cys_rich_CPXG PF14255.6 PVD29681.1 - 0.17 11.8 2.9 2.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.7 PVD29681.1 - 0.17 11.9 12.1 1.7 8.7 11.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 PVD29681.1 - 0.17 12.3 0.8 0.17 12.3 0.8 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 PVD29681.1 - 0.19 11.2 5.7 2.4 7.7 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain UBZ_FAAP20 PF15750.5 PVD29681.1 - 0.3 11.0 5.7 0.39 10.7 0.5 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Zn-ribbon_8 PF09723.10 PVD29681.1 - 0.51 10.5 8.2 3.8 7.7 8.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 PVD29681.1 - 0.93 9.1 5.2 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Ogr_Delta PF04606.12 PVD29681.1 - 1.3 9.1 0.1 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 PVD29681.1 - 1.6 9.3 9.3 1.2 9.7 0.6 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Prok-RING_1 PF14446.6 PVD29681.1 - 2.1 8.3 11.0 5 7.1 6.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_SprT PF17283.2 PVD29681.1 - 2.5 8.1 11.9 1.3 9.0 2.2 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 PVD29681.1 - 3.3 8.4 5.3 7.5 7.3 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2 PF00096.26 PVD29682.1 - 4.5e-12 45.7 43.8 0.013 15.9 1.0 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29682.1 - 5.3e-08 33.1 39.5 0.063 14.1 0.9 6.0 5 0 0 5 5 5 5 C2H2-type zinc finger zf-BED PF02892.15 PVD29682.1 - 2.8e-05 24.1 26.9 0.41 10.7 0.6 5.4 5 0 0 5 5 5 4 BED zinc finger zf-C2H2_11 PF16622.5 PVD29682.1 - 0.00055 19.6 37.0 0.61 9.9 6.9 5.9 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 PVD29682.1 - 0.0072 16.7 31.4 1.2 9.7 1.9 6.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2HC_2 PF13913.6 PVD29682.1 - 0.087 12.8 0.5 0.087 12.8 0.5 6.2 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 PVD29682.1 - 0.23 12.2 15.8 3.8 8.2 1.5 4.2 3 2 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats XPA_N PF01286.18 PVD29682.1 - 0.28 11.3 12.5 5 7.3 0.0 4.8 5 0 0 5 5 5 0 XPA protein N-terminal zf-met PF12874.7 PVD29682.1 - 1.6 9.3 21.4 3.9 8.0 0.1 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 PVD29682.1 - 2.1 9.1 21.7 1.8 9.4 2.0 3.4 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_6 PF13912.6 PVD29682.1 - 2.4 8.2 19.9 0.31 11.1 2.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger CpXC PF14353.6 PVD29682.1 - 3.1 7.9 18.2 4.9 7.2 0.2 4.5 3 2 1 4 4 4 0 CpXC protein Zn-ribbon_8 PF09723.10 PVD29682.1 - 3.4 7.9 29.3 27 5.0 2.8 5.4 3 2 1 4 4 4 0 Zinc ribbon domain DUF2256 PF10013.9 PVD29682.1 - 9.1 6.5 17.0 12 6.1 0.1 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2 PF00096.26 PVD29683.1 - 0.00028 21.2 75.6 0.046 14.2 0.6 13.0 13 0 0 13 13 13 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD29683.1 - 0.014 15.8 0.2 0.014 15.8 0.2 11.5 12 0 0 12 12 12 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 PVD29683.1 - 0.023 14.4 47.5 0.12 12.2 0.1 8.7 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PVD29683.1 - 0.45 11.5 87.8 0.044 14.6 2.2 13.0 13 0 0 13 13 13 0 C2H2-type zinc finger zf-met PF12874.7 PVD29683.1 - 0.75 10.3 0.0 0.75 10.3 0.0 8.0 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 PVD29683.1 - 4.5 7.5 8.0 17 5.6 0.6 4.1 3 0 0 3 3 3 0 Zinc-binding zf-C2H2 PF00096.26 PVD29684.1 - 1.1e-09 38.1 8.5 1.5e-05 25.2 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29684.1 - 5.5e-06 26.8 8.5 0.013 16.3 0.3 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 PVD29684.1 - 0.015 15.7 0.1 0.015 15.7 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD29684.1 - 0.076 13.3 1.2 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD29684.1 - 0.13 12.8 0.5 0.13 12.8 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain HypA PF01155.19 PVD29684.1 - 0.26 11.3 2.4 0.36 10.9 2.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 PVD29684.1 - 0.42 10.4 12.0 2.4 8.0 4.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 PVD29684.1 - 0.45 10.7 6.9 7.7 6.7 0.1 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD29684.1 - 0.5 10.7 4.9 4.4 7.7 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 PVD29684.1 - 0.82 9.6 3.2 13 5.8 0.1 2.7 2 1 1 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 PVD29684.1 - 7.6 6.6 11.8 13 5.9 4.8 2.3 1 1 1 2 2 2 0 BED zinc finger FLYWCH PF04500.16 PVD29687.1 - 4.3e-09 36.4 11.1 6.2e-09 35.8 3.1 2.7 3 0 0 3 3 2 1 FLYWCH zinc finger domain zf-C2H2_6 PF13912.6 PVD29687.1 - 2.8e-06 27.2 2.5 0.017 15.1 0.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD29687.1 - 1.3e-05 25.4 11.0 0.005 17.2 0.0 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29687.1 - 6.9e-05 23.4 19.6 0.0021 18.7 0.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD29687.1 - 0.00051 19.7 5.5 0.0035 17.0 0.2 3.2 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 PVD29687.1 - 0.0028 18.3 0.3 2.5 8.8 0.0 2.7 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 PVD29687.1 - 0.024 14.9 0.4 0.024 14.9 0.4 2.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 PVD29687.1 - 0.03 14.7 1.1 5.5 7.4 0.1 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 PVD29687.1 - 0.037 14.5 3.4 0.55 10.7 0.0 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 PVD29687.1 - 0.1 12.5 17.9 0.28 11.1 2.6 4.3 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf_C2H2_10 PF18414.1 PVD29687.1 - 0.66 9.6 3.6 4.2 7.0 0.5 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-C2HC_2 PF13913.6 PVD29687.1 - 4 7.5 9.7 1.2 9.1 1.6 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 PVD29688.1 - 0.00023 20.8 1.4 0.00023 20.8 1.4 1.9 2 1 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD29688.1 - 0.0031 17.9 8.1 0.023 15.2 1.0 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type OrsD PF12013.8 PVD29688.1 - 0.0057 17.1 3.5 0.006 17.0 3.0 1.3 1 1 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 PVD29688.1 - 0.039 14.8 0.9 0.039 14.8 0.9 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PVD29688.1 - 0.25 11.7 4.7 0.27 11.6 1.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 PVD29688.1 - 2.9 8.5 6.5 2.1 8.9 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 PVD29689.1 - 0.00013 22.2 10.4 0.047 14.2 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD29689.1 - 0.00089 19.0 4.2 0.0016 18.1 4.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD29689.1 - 0.0012 19.5 11.4 0.084 13.7 2.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_12 PF18658.1 PVD29689.1 - 0.012 15.2 1.2 0.024 14.2 0.5 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD29689.1 - 0.014 15.4 7.8 0.053 13.5 0.2 2.9 3 1 0 3 3 3 0 C2H2-type zinc finger Lar_restr_allev PF14354.6 PVD29689.1 - 0.11 12.9 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf_C2H2_ZHX PF18387.1 PVD29689.1 - 0.12 12.1 0.4 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 PVD29689.1 - 0.37 11.2 2.3 0.39 11.1 0.5 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 PVD29689.1 - 0.48 10.2 6.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 PVD29689.1 - 0.64 10.6 4.1 1.5 9.4 4.1 1.6 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-H2C2_2 PF13465.6 PVD29689.1 - 4 8.0 8.3 4.5 7.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 PVD29690.1 - 2.7e-09 37.0 32.2 0.026 15.0 1.8 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29690.1 - 9.1e-09 35.4 32.4 0.04 14.8 1.6 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD29690.1 - 0.00013 22.2 27.0 0.0019 18.5 0.4 6.0 6 0 0 6 6 5 3 Zinc-finger double domain zf-met PF12874.7 PVD29690.1 - 0.013 15.9 15.6 1.4 9.4 0.3 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 PVD29690.1 - 0.024 14.8 13.5 3.1 8.0 0.5 4.1 2 2 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 PVD29690.1 - 0.14 12.2 0.5 0.14 12.2 0.5 5.8 5 2 1 6 6 6 0 BED zinc finger DUF1451 PF07295.11 PVD29690.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.8 4 0 0 4 4 4 0 Zinc-ribbon containing domain HNH_5 PF14279.6 PVD29690.1 - 0.29 11.0 10.1 4.2 7.3 2.8 4.4 4 1 0 4 4 4 0 HNH endonuclease zf-met2 PF12907.7 PVD29690.1 - 0.52 10.5 5.2 0.46 10.7 1.0 2.6 2 0 0 2 2 2 0 Zinc-binding PyrI_C PF02748.15 PVD29690.1 - 0.65 10.0 6.4 0.4 10.6 0.2 3.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 PVD29690.1 - 0.7 10.3 18.8 1.7 9.0 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.6 PVD29690.1 - 0.79 9.5 9.5 22 4.9 5.0 3.9 2 1 1 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 PVD29690.1 - 1.3 9.4 19.6 5.8 7.3 1.4 4.3 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 PVD29690.1 - 4 7.4 13.5 63 3.6 0.2 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2H2 PF00096.26 PVD29691.1 - 1.9e-24 84.7 70.5 3.8e-05 23.9 0.6 9.5 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29691.1 - 1.2e-19 69.3 72.1 0.00048 20.7 0.4 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD29691.1 - 1.2e-07 31.6 1.5 0.00045 20.1 0.2 8.1 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD29691.1 - 1.5e-05 24.6 48.9 0.0013 18.4 3.0 6.4 7 0 0 7 7 7 4 zinc-finger C2H2-type zf-BED PF02892.15 PVD29691.1 - 0.0005 20.0 32.3 0.085 12.9 1.5 7.1 7 0 0 7 7 7 3 BED zinc finger zf-C2H2_jaz PF12171.8 PVD29691.1 - 0.0089 16.3 31.0 0.15 12.4 1.1 6.2 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD29691.1 - 0.012 16.0 0.2 0.012 16.0 0.2 10.0 12 0 0 12 12 11 0 Zinc-finger double domain GAGA PF09237.11 PVD29691.1 - 0.21 11.4 26.7 1.3 8.9 0.1 6.9 8 0 0 8 8 8 0 GAGA factor CxC5 PF18718.1 PVD29691.1 - 0.55 10.3 0.0 0.55 10.3 0.0 3.9 3 1 0 3 3 3 0 CxC5 like cysteine cluster associated with KDZ transposases zf-met PF12874.7 PVD29691.1 - 1.9 9.0 38.6 4.6 7.8 0.3 7.9 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 PVD29691.1 - 2.2 9.0 28.7 0.24 12.1 1.3 5.9 3 2 2 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 PVD29692.1 - 8.6e-12 44.8 55.2 0.0017 18.7 9.0 7.7 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD29692.1 - 5.8e-11 42.3 54.1 0.036 14.9 7.2 8.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD29692.1 - 0.0022 17.9 0.2 0.0022 17.9 0.2 7.0 7 0 0 7 7 7 4 C2H2-type zinc finger GAGA PF09237.11 PVD29692.1 - 0.0047 16.7 11.4 0.21 11.4 0.4 4.4 5 0 0 5 5 5 2 GAGA factor zf-Di19 PF05605.12 PVD29692.1 - 0.0093 16.2 1.1 0.0093 16.2 1.1 5.7 5 1 0 5 5 5 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 PVD29692.1 - 0.011 15.7 24.8 0.25 11.4 2.2 6.1 5 1 0 5 5 5 0 BED zinc finger BolA PF01722.18 PVD29692.1 - 0.034 14.4 1.0 4.7 7.6 0.0 3.9 4 1 0 4 4 4 0 BolA-like protein zf-C2H2_3rep PF18868.1 PVD29692.1 - 0.21 12.3 23.2 0.39 11.4 5.1 5.8 5 2 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 PVD29692.1 - 3.1 8.3 43.8 0.16 12.4 1.1 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 PVD29692.1 - 3.2 7.9 17.4 0.28 11.3 0.3 5.1 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2HE PF16278.5 PVD29692.1 - 3.3 8.2 19.3 3.6 8.1 0.8 5.4 5 1 1 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger HTH_psq PF05225.16 PVD29694.1 - 1.4e-05 24.7 1.8 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 PVD29694.1 - 0.056 13.6 0.2 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2 PF00096.26 PVD29695.1 - 4.6e-06 26.8 11.6 0.022 15.2 0.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 PVD29695.1 - 3.1e-05 23.6 8.3 0.11 12.3 0.0 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PVD29695.1 - 0.00053 20.6 15.3 0.0092 16.7 0.2 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 PVD29695.1 - 0.017 15.6 0.2 0.049 14.1 0.0 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 PVD29695.1 - 0.04 12.5 1.2 0.063 11.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-met PF12874.7 PVD29695.1 - 0.089 13.2 7.4 2.1 8.8 0.3 3.3 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 PVD29695.1 - 0.093 12.9 2.2 0.39 10.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-binding zf-UBR PF02207.20 PVD29695.1 - 0.26 11.5 7.7 0.57 10.4 7.7 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_6 PF13912.6 PVD29695.1 - 0.34 11.0 6.1 1.6 8.8 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD29695.1 - 0.42 11.0 2.5 4.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 PVD29695.1 - 4.7 7.6 8.7 6.7 7.1 1.0 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 PVD29695.1 - 7.5 6.9 6.3 8.9 6.7 2.4 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 PVD29699.1 - 1.3e-07 31.8 20.1 0.034 15.0 0.5 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD29699.1 - 1.4e-07 31.6 19.0 0.0026 18.1 2.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 PVD29699.1 - 2.1e-06 27.9 11.3 0.0023 18.2 2.8 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 PVD29699.1 - 3.7e-05 23.9 8.3 0.019 15.4 0.6 4.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 PVD29699.1 - 0.00039 20.7 19.6 0.0062 16.9 3.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 PVD29699.1 - 0.0022 17.7 6.1 0.0046 16.7 1.1 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD29699.1 - 0.052 13.6 18.9 0.11 12.5 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 PVD29699.1 - 0.088 12.7 0.7 7.8 6.4 0.0 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 PVD29699.1 - 0.098 12.8 2.4 0.63 10.2 0.6 2.6 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 PVD29699.1 - 0.16 12.3 14.4 13 6.2 0.9 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 PVD29699.1 - 1.1 10.0 4.8 5.3 7.9 4.7 2.2 1 1 0 1 1 1 0 zinc-ribbon family EXOSC1 PF10447.9 PVD29699.1 - 1.4 9.5 3.8 0.98 10.1 0.6 2.4 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 DZR PF12773.7 PVD29699.1 - 1.5 8.9 7.3 5.3 7.2 4.6 2.5 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 PVD29699.1 - 2 8.5 7.7 37 4.5 0.4 3.7 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.6 PVD29699.1 - 2.1 8.3 7.7 3 7.9 4.2 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 HypA PF01155.19 PVD29699.1 - 2.2 8.3 5.2 9.5 6.3 4.2 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 PVD29699.1 - 2.8 8.3 18.8 0.52 10.7 3.8 3.7 2 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 PVD29699.1 - 2.9 8.0 14.8 25 5.0 2.2 3.8 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.11 PVD29699.1 - 4.2 7.4 7.5 8.4 6.4 1.6 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 PVD29699.1 - 4.7 6.7 7.5 14 5.3 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 PVD29699.1 - 9.9 5.9 6.1 8 6.2 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger WD40 PF00400.32 PVD29700.1 - 2.2e-15 56.8 21.7 0.001 19.8 0.1 10.2 11 0 0 11 11 11 6 WD domain, G-beta repeat VSP PF03302.13 PVD29702.1 - 0.17 10.7 0.9 0.28 10.0 0.9 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein EF1_GNE PF00736.19 PVD29703.1 - 2.5e-36 123.7 1.8 2.5e-36 123.7 1.8 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 PVD29703.1 - 2.2e-10 40.8 1.0 2.2e-10 40.8 1.0 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.4 PVD29703.1 - 0.0023 17.7 0.0 0.0071 16.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD29703.1 - 0.0028 17.8 0.4 0.0078 16.4 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain ANAPC15 PF15243.6 PVD29703.1 - 0.024 15.0 0.9 3.7 8.0 0.1 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 TT_ORF2 PF02957.15 PVD29703.1 - 0.052 14.5 0.5 0.091 13.7 0.5 1.4 1 0 0 1 1 1 0 TT viral ORF2 DUF937 PF06078.11 PVD29703.1 - 0.081 13.5 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Molybdopterin PF00384.22 PVD29704.1 - 3.8e-75 253.5 0.0 5.5e-74 249.7 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 PVD29704.1 - 1.6e-16 59.5 0.1 4.4e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 PVD29704.1 - 7e-15 54.8 0.3 7e-15 54.8 0.3 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 PVD29704.1 - 1.8e-12 47.7 0.1 4.5e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 PVD29704.1 - 1.4e-08 34.5 0.2 1.4e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 PVD29704.1 - 0.0012 18.5 0.3 0.46 10.2 0.0 2.8 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain AA_permease_2 PF13520.6 PVD29705.1 - 6.1e-36 124.2 17.0 7.4e-36 123.9 17.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD29705.1 - 7.6e-20 71.0 17.6 1e-19 70.6 17.6 1.0 1 0 0 1 1 1 1 Amino acid permease RRM_1 PF00076.22 PVD29707.1 - 9.2e-20 70.3 0.0 1.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 PVD29707.1 - 0.059 12.9 38.6 0.077 12.6 38.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DEAD PF00270.29 PVD29708.1 - 2.7e-20 72.9 0.2 6.6e-20 71.6 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PVD29708.1 - 9.1e-19 68.1 1.0 2.5e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CARD_2 PF16739.5 PVD29708.1 - 8e-16 57.8 6.2 3.5e-12 46.1 0.2 3.1 3 1 1 4 4 4 2 Caspase recruitment domain SWI2_SNF2 PF18766.1 PVD29708.1 - 7.5e-07 29.0 2.0 5.2e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 PVD29708.1 - 0.00011 22.5 0.1 0.0092 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD29708.1 - 0.00014 22.2 1.6 0.016 15.5 0.1 3.2 2 2 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PVD29708.1 - 0.0062 15.8 1.1 0.04 13.2 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 PVD29708.1 - 0.0066 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 PVD29708.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 PVD29708.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD29708.1 - 0.028 14.2 0.0 0.13 11.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain Transket_pyr PF02779.24 PVD29708.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain NACHT PF05729.12 PVD29708.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PSD4 PF07631.11 PVD29708.1 - 0.66 10.5 4.4 0.69 10.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) UvrD-helicase PF00580.21 PVD29708.1 - 8.1 5.9 8.8 0.76 9.2 0.1 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain RIG-I_C-RD PF11648.8 PVD29709.1 - 3.7e-31 107.8 3.7 2.2e-30 105.3 0.5 2.3 2 0 0 2 2 2 1 C-terminal domain of RIG-I Helicase_C PF00271.31 PVD29709.1 - 5.9e-19 68.5 0.2 2.4e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RIG-I_C PF18119.1 PVD29709.1 - 2e-14 53.8 0.1 2e-14 53.8 0.1 3.0 2 1 1 3 3 3 1 RIG-I receptor C-terminal domain Yippee-Mis18 PF03226.14 PVD29709.1 - 0.006 16.8 0.7 0.02 15.1 0.7 1.9 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Selenoprotein_S PF06936.11 PVD29709.1 - 0.21 11.4 1.9 0.38 10.6 1.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Transferrin PF00405.17 PVD29710.1 - 2.9e-138 460.6 0.6 2e-78 263.9 0.0 2.1 2 0 0 2 2 2 2 Transferrin PRELI PF04707.14 PVD29710.1 - 4.6e-44 150.0 0.0 8.4e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 PRELI-like family Phosphonate-bd PF12974.7 PVD29710.1 - 3.4e-12 46.5 0.0 3.6e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 PVD29711.1 - 8.3e-43 146.7 23.8 2.7e-42 145.0 23.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 PVD29711.1 - 0.33 9.8 22.2 4.5 6.0 11.8 3.7 2 1 0 2 2 2 0 MFS_1 like family DUF4293 PF14126.6 PVD29711.1 - 2.2 8.5 8.8 10 6.4 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) TUDOR PF00567.24 PVD29712.1 - 3.8e-19 68.9 0.2 4e-18 65.6 0.0 2.7 2 0 0 2 2 2 1 Tudor domain zf-CCHC PF00098.23 PVD29712.1 - 0.0034 17.4 0.9 0.0084 16.2 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Tudor-knot PF11717.8 PVD29712.1 - 0.0054 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-CCHC_3 PF13917.6 PVD29712.1 - 0.0057 16.6 1.3 0.015 15.3 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle CybS PF05328.12 PVD29713.1 - 4.5e-21 74.9 3.9 6e-21 74.5 3.9 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Kinesin PF00225.23 PVD29714.1 - 2.5e-99 332.4 0.6 5.7e-99 331.2 0.6 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD29714.1 - 4.8e-18 65.5 0.3 1.8e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 PVD29714.1 - 4.7e-07 30.1 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 PVD29714.1 - 0.00018 21.7 0.2 0.00018 21.7 0.2 4.4 3 1 1 4 4 4 1 Kinesin-associated Yop-YscD_cpl PF16697.5 PVD29714.1 - 0.00047 20.4 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 PVD29714.1 - 0.0015 18.9 0.1 0.0015 18.9 0.1 2.7 3 0 0 3 3 3 1 Kinesin protein 1B AAA_32 PF13654.6 PVD29714.1 - 0.002 17.0 6.5 0.017 13.9 5.4 2.2 2 0 0 2 2 2 1 AAA domain DUF2095 PF09868.9 PVD29714.1 - 0.019 14.9 1.4 0.042 13.8 1.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DUF883 PF05957.13 PVD29714.1 - 0.14 12.8 2.8 0.66 10.6 2.8 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 PVD29714.1 - 0.41 10.7 6.3 0.92 9.6 6.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Homeodomain PF00046.29 PVD29715.1 - 1.6e-21 75.9 6.6 2.5e-21 75.3 6.6 1.3 1 0 0 1 1 1 1 Homeodomain Casein_kappa PF00997.18 PVD29715.1 - 0.027 14.6 0.3 0.041 14.0 0.3 1.2 1 0 0 1 1 1 0 Kappa casein Homeobox_KN PF05920.11 PVD29715.1 - 0.073 13.0 0.3 0.19 11.6 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain T4SS_CagC PF16943.5 PVD29716.1 - 0.25 11.5 4.1 0.54 10.4 1.0 2.5 2 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system Orf78 PF06024.12 PVD29716.1 - 0.44 10.9 1.9 14 6.0 1.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) ODV-E18 PF10717.9 PVD29716.1 - 1.5 8.8 3.6 2.2 8.2 1.7 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2116 PF09889.9 PVD29716.1 - 9 6.4 8.1 30 4.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Homeodomain PF00046.29 PVD29717.1 - 2.1e-21 75.5 8.0 4.1e-21 74.6 8.0 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD29717.1 - 0.00034 20.0 1.1 0.00056 19.3 0.2 1.8 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PVD29717.1 - 0.013 15.4 0.3 0.013 15.4 0.3 2.2 2 1 0 2 2 2 0 Homeobox KN domain Flu_NS2 PF00601.19 PVD29717.1 - 0.053 13.8 1.4 0.15 12.4 1.1 2.1 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) UPF0172 PF03665.13 PVD29717.1 - 0.063 13.3 0.2 0.077 13.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) YdaS_antitoxin PF15943.5 PVD29717.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CPSase_L_D3 PF02787.19 PVD29717.1 - 0.089 13.1 1.1 0.13 12.7 1.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MAM PF00629.23 PVD29718.1 - 2.3e-24 86.1 0.0 3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu CCDC92 PF14916.6 PVD29719.1 - 0.0047 16.7 7.4 0.14 12.0 0.1 3.6 3 1 1 4 4 4 2 Coiled-coil domain of unknown function ATG16 PF08614.11 PVD29719.1 - 0.028 14.7 27.6 0.063 13.5 9.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 PVD29719.1 - 0.12 12.7 15.5 0.065 13.5 1.3 3.8 3 1 0 4 4 4 0 ABC transporter C-terminal domain AAA_31 PF13614.6 PVD29719.1 - 0.24 11.3 6.9 0.12 12.2 1.7 2.2 1 1 1 2 2 2 0 AAA domain Filament PF00038.21 PVD29719.1 - 0.52 9.8 24.0 0.93 9.0 15.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 PVD29719.1 - 0.96 8.3 25.4 0.23 10.3 11.0 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein HalX PF08663.10 PVD29719.1 - 1.2 9.5 11.1 1.5 9.2 0.3 4.3 4 1 0 4 4 4 0 HalX domain NPV_P10 PF05531.12 PVD29719.1 - 1.9 9.0 12.0 3.2 8.3 0.9 3.7 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein BBS1 PF14779.6 PVD29719.1 - 4 6.8 6.7 2 7.8 4.2 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 Fez1 PF06818.15 PVD29719.1 - 7.5 7.0 25.9 1.1 9.6 6.6 2.8 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 PVD29719.1 - 9 7.0 26.9 36 5.1 8.9 3.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Glycos_transf_2 PF00535.26 PVD29720.1 - 8.9e-30 103.7 0.0 1.5e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD29720.1 - 4.6e-15 56.0 4.1 8.8e-15 55.1 4.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PVD29720.1 - 6.2e-05 23.0 0.0 9.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD29720.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 PVD29720.1 - 0.0018 19.0 0.1 0.21 12.3 0.1 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like zf-C4 PF00105.18 PVD29721.1 - 2.6e-22 79.1 12.3 6.6e-22 77.8 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29721.1 - 1.1e-12 48.0 0.6 5.1e-12 45.8 0.6 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.16 PVD29721.1 - 2.2 8.6 5.5 4.2 7.8 0.6 2.7 2 0 0 2 2 2 0 C1 domain zf-C4 PF00105.18 PVD29722.1 - 2.8e-22 78.9 12.7 6.6e-22 77.8 12.7 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29722.1 - 2.8e-06 27.1 0.8 9.7e-06 25.3 0.8 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SPATIAL PF15256.6 PVD29722.1 - 0.054 13.8 0.2 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 SPATIAL MCM_bind PF09739.9 PVD29723.1 - 6.2e-186 619.3 0.0 7.1e-186 619.1 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 PVD29723.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain BCIP PF13862.6 PVD29724.1 - 7.2e-45 153.3 3.6 1.2e-44 152.6 3.6 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF4421 PF14391.6 PVD29724.1 - 0.06 12.7 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) MazG PF03819.17 PVD29724.1 - 0.094 12.9 4.2 0.39 10.9 0.1 2.5 1 1 1 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain HA2 PF04408.23 PVD29725.1 - 2.2e-24 85.8 0.2 4.8e-24 84.7 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD29725.1 - 1.4e-22 79.8 0.1 4.7e-22 78.2 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD29725.1 - 1.1e-12 48.2 0.0 3.4e-12 46.7 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD29725.1 - 2e-08 34.2 0.2 4e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PVD29725.1 - 7e-06 26.4 0.1 1.8e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD29725.1 - 1.6e-05 25.2 0.2 0.00012 22.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 PVD29725.1 - 0.0011 18.6 0.2 0.0055 16.4 0.2 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 PVD29725.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 PVD29725.1 - 0.0063 16.5 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PVD29725.1 - 0.0086 15.8 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PVD29725.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 PVD29725.1 - 0.026 14.1 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 PVD29725.1 - 0.038 14.5 0.7 0.41 11.2 0.0 2.7 3 0 0 3 3 3 0 ABC transporter HTH_IclR PF09339.10 PVD29725.1 - 0.047 13.5 0.2 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain NACHT PF05729.12 PVD29725.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 PVD29725.1 - 0.062 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 PVD29725.1 - 0.072 12.8 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 PVD29725.1 - 0.1 12.4 0.3 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 PVD29725.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase2 PF18747.1 PVD29725.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 THEG PF14912.6 PVD29726.1 - 4.6e-49 164.7 21.5 1.2e-14 54.5 0.1 6.4 5 2 2 7 7 7 7 Testicular haploid expressed repeat HIG_1_N PF04588.13 PVD29727.1 - 1.6e-20 73.0 0.9 2e-20 72.7 0.9 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Lectin_C PF00059.21 PVD29728.1 - 8e-61 203.5 23.7 1.7e-15 57.6 0.3 4.6 3 1 2 5 5 5 4 Lectin C-type domain Chordopox_A33R PF05966.12 PVD29728.1 - 0.33 10.2 4.6 0.79 9.0 0.2 2.6 3 0 0 3 3 3 0 Chordopoxvirus A33R protein UL45 PF05473.12 PVD29728.1 - 8.4 6.0 16.9 0.15 11.6 1.7 4.4 4 1 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD29729.1 - 4e-15 56.5 0.0 8.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 PVD29730.1 - 1.1e-83 277.1 34.1 7.6e-14 52.4 0.2 7.6 7 0 0 7 7 7 7 Lectin C-type domain UL45 PF05473.12 PVD29730.1 - 1.1e-07 31.7 9.9 1.2e-05 25.1 0.6 5.1 5 0 0 5 5 5 2 UL45 protein, carbohydrate-binding C-type lectin-like BACK PF07707.15 PVD29730.1 - 3.8e-06 26.9 0.4 8.6e-06 25.8 0.4 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Xlink PF00193.17 PVD29730.1 - 1.6 9.1 9.2 3.1 8.2 0.1 5.3 6 1 1 7 7 7 0 Extracellular link domain DUF747 PF05346.11 PVD29731.1 - 9.1e-105 350.6 20.1 1.3e-104 350.1 20.1 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 PVD29731.1 - 1.5 9.9 0.0 1.5 9.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) U-box PF04564.15 PVD29732.1 - 2.3e-16 59.7 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4 PF00097.25 PVD29732.1 - 0.00017 21.4 13.5 0.00066 19.5 13.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD29732.1 - 0.00057 20.2 12.3 0.0033 17.7 12.3 2.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD29732.1 - 0.0011 18.9 13.7 0.0011 18.9 13.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 PVD29732.1 - 0.0027 17.5 10.7 0.0068 16.2 10.7 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 PVD29732.1 - 0.0053 16.6 11.5 0.027 14.3 11.5 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD29732.1 - 0.033 14.0 14.6 0.099 12.5 14.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD29732.1 - 0.14 12.3 9.2 0.24 11.4 7.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DUF1272 PF06906.11 PVD29732.1 - 6.7 6.9 12.1 20 5.4 12.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HTH_Tnp_1 PF01527.20 PVD29733.1 - 7.2e-13 48.7 18.7 2 8.8 0.0 11.3 10 3 2 12 12 12 4 Transposase HTH_23 PF13384.6 PVD29733.1 - 3e-12 46.0 12.8 0.59 10.0 0.3 8.4 9 0 0 9 9 9 5 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 PVD29733.1 - 3.4e-06 27.2 9.8 5.4 7.2 0.1 6.4 6 0 0 6 6 6 3 Helix-turn-helix of insertion element transposase HTH_28 PF13518.6 PVD29733.1 - 2.7e-05 24.2 18.5 0.13 12.4 0.2 7.0 7 0 0 7 7 7 3 Helix-turn-helix domain HTH_29 PF13551.6 PVD29733.1 - 0.00024 21.0 13.8 16 5.6 0.0 7.7 8 0 0 8 8 8 1 Winged helix-turn helix HTH_17 PF12728.7 PVD29733.1 - 0.013 15.6 0.7 37 4.6 0.0 4.2 5 0 0 5 5 5 0 Helix-turn-helix domain Lectin_C PF00059.21 PVD29734.1 - 0.00022 21.9 2.2 0.023 15.4 0.0 3.7 3 1 1 4 4 4 2 Lectin C-type domain Lectin_C PF00059.21 PVD29735.1 - 0.017 15.8 4.1 0.2 12.4 0.0 3.0 2 1 1 3 3 3 0 Lectin C-type domain PAN_1 PF00024.26 PVD29735.1 - 1.1 9.3 18.7 0.12 12.3 11.4 2.5 2 0 0 2 2 2 0 PAN domain Homeodomain PF00046.29 PVD29737.1 - 2.1e-21 75.5 5.2 3.3e-21 74.9 5.2 1.3 1 0 0 1 1 1 1 Homeodomain PBP1_TM PF14812.6 PVD29737.1 - 3 8.3 20.2 3.3 8.1 3.7 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Heme_oxygenase PF01126.20 PVD29738.1 - 2e-56 191.0 1.0 2.7e-56 190.6 1.0 1.2 1 0 0 1 1 1 1 Heme oxygenase Gp-FAR-1 PF05823.12 PVD29738.1 - 0.053 13.9 1.2 0.68 10.3 0.1 2.6 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Heme_oxygenase PF01126.20 PVD29739.1 - 1.1e-57 195.1 0.7 1.6e-57 194.6 0.7 1.2 1 0 0 1 1 1 1 Heme oxygenase WD40 PF00400.32 PVD29740.1 - 1e-11 45.2 2.2 2.8 9.0 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD29740.1 - 0.0038 17.5 0.0 15 5.9 0.0 4.7 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_2_N PF02837.18 PVD29741.1 - 0.023 14.6 0.4 0.039 13.9 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Pkinase PF00069.25 PVD29743.1 - 1.3e-57 195.2 1.5 1.9e-57 194.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29743.1 - 2e-32 112.5 0.1 7.1e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase zf-UBR PF02207.20 PVD29744.1 - 5.1e-18 65.0 9.3 5.1e-18 65.0 9.3 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) HscB_4_cys PF18256.1 PVD29744.1 - 0.021 14.7 0.2 0.068 13.0 0.2 2.0 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif BRCT PF00533.26 PVD29745.1 - 2.7e-12 46.9 1.1 1.2e-05 25.6 0.0 3.6 3 1 0 3 3 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD29745.1 - 3.9e-11 43.2 0.0 0.0001 22.7 0.0 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4 PF00097.25 PVD29745.1 - 2.5e-06 27.3 18.4 2.5e-06 27.2 15.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD29745.1 - 2.8e-06 27.1 15.6 1e-05 25.2 15.6 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD29745.1 - 4.2e-06 26.5 12.8 1.3e-05 24.9 12.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD29745.1 - 1.5e-05 25.0 12.0 2.4e-05 24.3 10.4 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 PVD29745.1 - 3.5e-05 23.6 3.6 0.00013 21.8 3.6 2.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 PVD29745.1 - 3.7e-05 24.0 15.4 0.00017 21.9 15.4 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD29745.1 - 3.9e-05 23.7 14.9 0.00018 21.6 14.9 2.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD29745.1 - 5.3e-05 23.1 14.8 0.00019 21.3 14.8 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 PVD29745.1 - 0.00048 19.9 9.2 0.0026 17.5 9.2 2.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 PVD29745.1 - 0.0023 18.0 7.7 0.011 15.8 7.7 2.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 PVD29745.1 - 0.031 14.1 13.3 0.1 12.5 13.3 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PVD29745.1 - 0.11 12.8 9.9 0.83 10.0 9.9 2.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PVD29745.1 - 0.46 10.6 4.6 1.6 8.9 4.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ras PF00071.22 PVD29746.1 - 6.5e-38 129.9 0.0 9.1e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD29746.1 - 1.7e-21 76.7 0.0 4.1e-21 75.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD29746.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD29746.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD29746.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NIF PF03031.18 PVD29747.1 - 4.7e-29 101.2 0.2 7.3e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 PVD29747.1 - 1e-05 25.2 0.1 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PVD29747.1 - 0.00032 21.1 0.4 0.0095 16.4 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PVD29747.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Pox_Ag35 PF03286.14 PVD29747.1 - 0.38 10.5 2.0 0.71 9.6 2.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 PVD29747.1 - 9.8 6.6 11.6 45 4.5 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prominin PF05478.11 PVD29748.1 - 5.6e-105 352.1 7.6 3.2e-37 128.0 2.8 3.0 1 1 1 3 3 3 3 Prominin Tweety PF04906.13 PVD29748.1 - 2.5e-05 23.1 12.2 0.0012 17.7 0.0 3.5 4 0 0 4 4 4 2 Tweety Baculo_PEP_C PF04513.12 PVD29748.1 - 0.0014 18.7 22.8 0.15 12.1 11.2 4.5 2 2 3 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2207 PF09972.9 PVD29748.1 - 0.048 12.4 0.0 0.048 12.4 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF999 PF06198.11 PVD29748.1 - 0.07 13.1 0.2 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF999) H-kinase_dim PF02895.14 PVD29748.1 - 0.091 13.2 1.9 19 5.7 0.0 3.6 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain TMF_TATA_bd PF12325.8 PVD29748.1 - 0.099 12.9 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MetW PF07021.12 PVD29748.1 - 0.11 12.0 0.2 0.78 9.3 0.1 2.1 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW Syntaxin PF00804.25 PVD29748.1 - 0.14 11.9 1.5 0.38 10.4 0.4 2.1 2 0 0 2 2 2 0 Syntaxin Sec34 PF04136.15 PVD29748.1 - 0.2 11.5 2.1 0.72 9.7 0.5 2.7 3 0 0 3 3 3 0 Sec34-like family AIP3 PF03915.13 PVD29748.1 - 0.25 10.4 7.6 0.41 9.7 1.1 2.6 2 1 0 2 2 2 0 Actin interacting protein 3 Dynactin_p22 PF07426.11 PVD29748.1 - 0.3 11.0 1.3 0.54 10.1 0.1 2.1 3 0 0 3 3 3 0 Dynactin subunit p22 APG17 PF04108.12 PVD29748.1 - 0.37 9.9 3.1 1.1 8.3 0.5 2.2 2 1 0 2 2 2 0 Autophagy protein Apg17 Fib_alpha PF08702.10 PVD29748.1 - 0.48 10.6 8.5 1.8 8.8 0.8 3.6 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 PVD29748.1 - 1.3 9.3 10.3 0.87 9.9 0.2 4.5 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 PVD29748.1 - 3.3 7.8 6.6 2.3 8.3 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 PVD29748.1 - 7.3 6.0 7.3 2.1 7.8 1.7 2.4 2 1 1 3 3 3 0 Allexivirus 40kDa protein Fringe PF02434.16 PVD29749.1 - 1.7e-13 50.6 0.9 1.2e-12 47.8 0.9 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD29749.1 - 4.6e-10 39.7 0.0 4.9e-06 26.5 0.1 2.7 1 1 2 3 3 3 2 Galactosyltransferase Prominin PF05478.11 PVD29751.1 - 1.5e-06 26.5 0.1 0.00069 17.7 0.0 2.3 2 0 0 2 2 2 2 Prominin DUF1870 PF08965.10 PVD29751.1 - 0.1 12.6 0.0 0.54 10.3 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1870) SUIM_assoc PF16619.5 PVD29751.1 - 0.28 11.3 13.3 0.13 12.4 10.2 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pea-VEAacid PF08111.11 PVD29751.1 - 0.35 11.3 1.7 1.2 9.6 1.2 2.2 2 0 0 2 2 2 0 Pea-VEAacid family PspB PF06667.12 PVD29751.1 - 0.97 9.5 0.0 0.97 9.5 0.0 2.5 2 0 0 2 2 2 0 Phage shock protein B M_domain PF12938.7 PVD29751.1 - 2.1 8.1 16.5 3.6 7.3 16.5 1.3 1 0 0 1 1 1 0 M domain of GW182 Prominin PF05478.11 PVD29752.1 - 7.8e-110 368.1 19.4 6.1e-77 259.3 12.3 3.4 2 1 1 3 3 3 2 Prominin Tweety PF04906.13 PVD29752.1 - 6.5e-05 21.8 13.1 0.0048 15.6 0.0 3.5 3 0 0 3 3 3 2 Tweety Dynamin_M PF01031.20 PVD29752.1 - 0.0059 15.9 0.4 0.18 11.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region Yip1 PF04893.17 PVD29752.1 - 0.0096 15.7 4.3 0.084 12.6 0.4 3.0 3 1 1 4 4 4 1 Yip1 domain ETRAMP PF09716.10 PVD29752.1 - 0.016 15.2 0.1 2.4 8.3 0.0 3.7 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Oxidored_q3 PF00499.20 PVD29752.1 - 0.044 13.5 3.3 0.11 12.2 0.4 2.8 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CRIC_ras_sig PF10534.9 PVD29752.1 - 0.12 12.6 2.4 0.81 9.9 0.0 3.2 3 0 0 3 3 3 0 Connector enhancer of kinase suppressor of ras RPW8 PF05659.11 PVD29752.1 - 0.39 10.4 2.5 1.4 8.6 0.4 2.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TORC_C PF12886.7 PVD29752.1 - 0.82 10.3 4.1 18 6.0 0.1 3.8 4 0 0 4 4 4 0 Transducer of regulated CREB activity, C terminus Fringe PF02434.16 PVD29754.1 - 2.2e-14 53.5 0.5 1.2e-13 51.1 0.5 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD29754.1 - 7.3e-11 42.2 0.0 2.1e-06 27.7 0.3 2.8 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 PVD29755.1 - 3e-13 49.8 0.3 8.9e-12 45.0 0.7 2.6 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 PVD29755.1 - 4.5e-08 33.2 0.0 0.00075 19.4 0.1 2.6 1 1 1 3 3 3 2 Galactosyltransferase Peptidase_S51 PF03575.17 PVD29756.1 - 5.2e-08 32.8 0.0 1.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S51 SLATT_4 PF18186.1 PVD29756.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Lysyl_oxidase PF01186.17 PVD29758.1 - 1.6e-85 285.9 1.6 7.6e-75 251.1 0.6 2.4 2 0 0 2 2 2 2 Lysyl oxidase SRCR PF00530.18 PVD29758.1 - 5.6e-42 142.3 17.7 2.5e-23 82.4 0.7 3.1 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD29758.1 - 3.3e-07 30.8 4.9 0.011 16.2 1.0 3.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD29758.1 - 0.026 15.0 0.8 5.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Hepsin, SRCR domain Hamartin PF04388.12 PVD29758.1 - 3.8 6.0 10.2 4.7 5.8 10.2 1.1 1 0 0 1 1 1 0 Hamartin protein 7tm_1 PF00001.21 PVD29759.1 - 2.4e-42 145.1 27.4 3.1e-42 144.7 27.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) US10 PF17617.2 PVD29759.1 - 5.7 7.0 8.6 2.3 8.3 5.7 1.9 1 1 1 2 2 2 0 Viral unique short region 10 FAM53 PF15242.6 PVD29760.1 - 5.5e-17 62.5 20.4 2e-16 60.7 20.4 1.9 1 1 0 1 1 1 1 Family of FAM53 DPCD PF14913.6 PVD29761.1 - 0.017 14.5 0.4 0.027 13.8 0.4 1.2 1 0 0 1 1 1 0 DPCD protein family Cullin PF00888.22 PVD29762.1 - 4.9e-15 55.2 0.7 5.9e-15 54.9 0.7 1.1 1 0 0 1 1 1 1 Cullin family GLTP PF08718.11 PVD29762.1 - 0.032 14.5 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Helicase_IV_N PF12462.8 PVD29762.1 - 0.14 12.1 1.2 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal ParcG PF10274.9 PVD29764.1 - 6.6e-40 137.2 0.0 8.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HEAT_EZ PF13513.6 PVD29764.1 - 0.043 14.3 0.5 0.59 10.7 0.1 2.4 1 1 1 2 2 2 0 HEAT-like repeat TPR_2 PF07719.17 PVD29765.1 - 0.00038 20.4 13.9 0.16 12.2 0.5 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD29765.1 - 0.0069 16.9 10.4 0.93 10.1 0.4 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD29765.1 - 0.2 11.9 15.7 0.48 10.8 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Mitoc_mL59 PF18126.1 PVD29765.1 - 2 8.7 5.2 2.9 8.2 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein mL59 TPR_12 PF13424.6 PVD29765.1 - 8.9 6.7 18.0 0.59 10.5 1.9 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat QVR PF17064.5 PVD29766.1 - 7.3e-05 22.9 9.0 0.00025 21.2 9.0 1.9 1 1 0 1 1 1 1 Sleepless protein NSP10 PF09401.10 PVD29766.1 - 0.012 15.7 0.3 0.034 14.2 0.2 1.7 1 1 1 2 2 2 0 RNA synthesis protein NSP10 CENP-B_dimeris PF09026.10 PVD29767.1 - 0.0004 20.7 3.8 0.00052 20.3 3.8 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FYDLN_acid PF09538.10 PVD29767.1 - 0.0019 18.8 5.2 0.002 18.8 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) DUF2052 PF09747.9 PVD29767.1 - 0.0064 16.6 8.7 0.0067 16.6 8.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 PVD29767.1 - 0.013 15.1 6.1 0.015 15.0 6.1 1.1 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 PVD29767.1 - 0.028 13.5 11.6 0.026 13.5 11.6 1.1 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 PVD29767.1 - 0.037 13.9 5.3 0.042 13.8 5.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4471 PF14740.6 PVD29767.1 - 0.041 13.1 2.2 0.045 13.0 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4637 PF15470.6 PVD29767.1 - 0.044 13.5 8.4 0.047 13.4 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 PVD29767.1 - 0.047 11.9 9.3 0.047 11.9 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 PVD29767.1 - 0.052 13.7 3.9 0.057 13.6 3.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BSP_II PF05432.11 PVD29767.1 - 0.062 13.0 11.1 0.065 12.9 11.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NARP1 PF12569.8 PVD29767.1 - 0.067 12.1 4.6 0.064 12.1 4.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPA43_OB PF17875.1 PVD29767.1 - 0.071 13.7 2.2 0.065 13.9 2.2 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Pox_Ag35 PF03286.14 PVD29767.1 - 0.072 12.9 7.1 0.074 12.8 7.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PI3K_1B_p101 PF10486.9 PVD29767.1 - 0.072 10.9 4.0 0.07 10.9 4.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 PVD29767.1 - 0.076 11.1 12.3 0.077 11.1 12.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 PVD29767.1 - 0.078 12.7 10.2 0.083 12.6 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PPL5 PF18168.1 PVD29767.1 - 0.11 11.8 2.0 0.12 11.7 2.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF3464 PF11947.8 PVD29767.1 - 0.14 11.9 3.4 0.15 11.8 3.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MCU PF04678.13 PVD29767.1 - 0.16 12.0 2.8 0.19 11.8 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Eapp_C PF10238.9 PVD29767.1 - 0.17 12.0 5.7 0.2 11.7 5.7 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Radial_spoke PF04712.12 PVD29767.1 - 0.2 10.5 8.1 0.19 10.7 8.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RXT2_N PF08595.11 PVD29767.1 - 0.21 11.6 7.0 0.23 11.5 7.0 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 PVD29767.1 - 0.21 9.8 8.8 0.21 9.8 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 PVD29767.1 - 0.24 11.2 6.4 0.23 11.2 6.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Astro_capsid_p PF12226.8 PVD29767.1 - 0.26 10.4 5.1 0.27 10.4 5.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Phage_Gp23 PF10669.9 PVD29767.1 - 0.39 11.1 6.9 0.43 10.9 6.9 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RNA_pol_Rpc4 PF05132.14 PVD29767.1 - 0.48 10.8 3.9 0.52 10.7 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 MscS_TM PF12794.7 PVD29767.1 - 0.56 9.0 6.1 0.64 8.8 6.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Connexin PF00029.19 PVD29767.1 - 0.58 9.9 3.3 0.63 9.8 3.3 1.1 1 0 0 1 1 1 0 Connexin DUF2457 PF10446.9 PVD29767.1 - 0.6 9.2 14.8 0.67 9.0 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Roughex PF06020.11 PVD29767.1 - 0.68 9.0 6.8 0.69 8.9 6.8 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 PVD29767.1 - 0.72 8.6 3.1 0.7 8.6 3.1 1.0 1 0 0 1 1 1 0 Presenilin Fmp27 PF10344.9 PVD29767.1 - 1.2 7.2 3.3 1.1 7.2 3.3 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 OAD_gamma PF04277.13 PVD29767.1 - 1.2 9.8 4.5 1.6 9.3 4.5 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TRAP_alpha PF03896.16 PVD29767.1 - 1.4 8.1 6.3 1.4 8.0 6.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 PVD29767.1 - 1.5 7.3 6.6 1.4 7.4 6.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EIIBC-GUT_N PF03612.14 PVD29767.1 - 1.6 8.4 3.8 1.7 8.3 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Zip PF02535.22 PVD29767.1 - 2.1 7.5 3.0 2.4 7.3 3.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TFB6 PF17110.5 PVD29767.1 - 2.1 8.1 9.2 2.6 7.8 9.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CobT PF06213.12 PVD29767.1 - 2.2 7.6 16.0 2.9 7.2 16.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HSP90 PF00183.18 PVD29767.1 - 2.3 7.0 9.8 2.4 6.9 9.8 1.0 1 0 0 1 1 1 0 Hsp90 protein HECT PF00632.25 PVD29768.1 - 5.4e-46 157.5 0.0 8.4e-33 114.2 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) NLE PF08154.12 PVD29768.1 - 0.031 14.8 0.0 0.081 13.5 0.0 1.7 1 0 0 1 1 1 0 NLE (NUC135) domain DUF5034 PF16437.5 PVD29768.1 - 0.17 11.9 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) Ank_2 PF12796.7 PVD29769.1 - 1.2e-38 131.6 11.6 1.7e-13 50.9 0.2 5.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29769.1 - 2.2e-36 123.7 4.6 1.7e-11 44.4 0.1 8.4 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29769.1 - 3.4e-26 88.4 8.1 0.007 16.8 0.0 10.0 9 2 1 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 PVD29769.1 - 2.5e-21 75.5 6.4 1.5e-10 41.1 0.7 6.9 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD29769.1 - 2e-20 72.3 8.7 0.00047 20.5 0.0 8.4 7 1 1 8 8 8 5 Ankyrin repeat Amino_oxidase PF01593.24 PVD29770.1 - 5.4e-63 213.8 0.1 9e-62 209.8 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD29770.1 - 3.8e-14 52.7 2.6 9.6e-14 51.4 1.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PVD29770.1 - 2.3e-07 30.3 0.3 3.9e-07 29.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PVD29770.1 - 8.7e-06 25.5 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PVD29770.1 - 0.0001 21.6 3.9 0.00036 19.8 1.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PVD29770.1 - 0.001 18.5 0.3 0.0015 18.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PVD29770.1 - 0.0014 17.9 1.5 0.0023 17.2 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PVD29770.1 - 0.0042 16.4 1.3 0.0042 16.4 1.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 PVD29770.1 - 0.009 16.1 2.2 0.018 15.1 0.2 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 PVD29770.1 - 0.014 14.7 0.3 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 PVD29770.1 - 0.014 15.9 2.4 0.037 14.6 2.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD29770.1 - 0.019 13.7 2.2 0.043 12.5 2.2 1.6 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PVD29770.1 - 0.046 13.0 0.6 0.082 12.1 0.6 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 PVD29770.1 - 0.056 12.2 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 MCRA family IlvN PF07991.12 PVD29770.1 - 0.074 12.6 0.3 0.18 11.3 0.3 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 PVD29770.1 - 0.19 10.8 7.0 0.14 11.2 4.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 PVD29770.1 - 0.45 10.5 5.1 7.3 6.6 0.9 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 PVD29770.1 - 0.67 8.9 3.3 3.4 6.6 1.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 PVD29771.1 - 6.3e-38 131.2 0.0 1.5e-33 116.8 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Tetraspanin PF00335.20 PVD29772.1 - 7.9e-12 45.4 6.0 1e-11 45.0 6.0 1.0 1 0 0 1 1 1 1 Tetraspanin family TIC20 PF16166.5 PVD29772.1 - 0.034 13.9 0.4 0.041 13.7 0.4 1.1 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like PepSY_TM PF03929.16 PVD29772.1 - 0.19 11.4 0.7 0.25 11.0 0.7 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Glyco_transf_11 PF01531.16 PVD29773.1 - 8.9e-20 71.1 0.0 3.6e-18 65.8 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 11 NodZ PF05830.11 PVD29773.1 - 0.069 12.0 0.1 0.2 10.5 0.1 1.8 2 1 0 2 2 2 0 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PVD29773.1 - 0.27 9.8 0.3 3.1 6.3 0.0 2.4 3 0 0 3 3 3 0 Xyloglucan fucosyltransferase Tetraspanin PF00335.20 PVD29774.1 - 1.1e-38 133.2 6.6 2e-38 132.4 6.6 1.4 1 0 0 1 1 1 1 Tetraspanin family LapA_dom PF06305.11 PVD29774.1 - 3.9 7.4 5.2 1.3 8.9 0.2 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain IBN_N PF03810.19 PVD29775.1 - 4.4e-11 42.5 0.5 2e-10 40.4 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.11 PVD29775.1 - 0.009 15.2 2.1 0.075 12.2 0.5 2.5 2 0 0 2 2 2 1 CRM1 C terminal Rep_fac_C PF08542.11 PVD29775.1 - 0.022 15.2 0.1 2.7 8.4 0.0 4.0 5 0 0 5 5 5 0 Replication factor C C-terminal domain TetR_C_5 PF08360.11 PVD29775.1 - 0.074 13.2 0.1 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Sulfate_transp PF00916.20 PVD29776.1 - 1.2e-96 323.8 22.4 1.2e-96 323.8 22.4 1.5 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 PVD29776.1 - 3e-19 68.8 0.0 8.8e-19 67.3 0.0 1.9 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD29776.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 STAS domain DUF5336 PF17270.2 PVD29776.1 - 9.7 5.8 12.8 0.56 9.8 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5336) Sulfate_transp PF00916.20 PVD29777.1 - 1e-23 83.8 0.3 1.1e-23 83.6 0.3 1.0 1 0 0 1 1 1 1 Sulfate permease family Tim17 PF02466.19 PVD29777.1 - 0.016 15.6 0.1 0.25 11.7 0.0 2.2 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Sulfate_transp PF00916.20 PVD29778.1 - 1.3e-75 254.6 16.8 1.3e-75 254.6 16.8 1.3 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 PVD29778.1 - 7.4e-17 61.1 0.1 1.4e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain PHO4 PF01384.20 PVD29778.1 - 0.25 10.3 19.3 0.057 12.5 4.7 2.2 2 0 0 2 2 2 0 Phosphate transporter family BC10 PF06726.12 PVD29778.1 - 2.7 8.3 5.5 6.1 7.1 1.5 2.8 2 1 0 2 2 2 0 Bladder cancer-related protein BC10 Phage_holin_Dp1 PF16938.5 PVD29778.1 - 3.8 7.8 6.9 14 6.0 0.2 2.9 2 0 0 2 2 2 0 Putative phage holin Dp-1 fragilysinNterm PF16376.5 PVD29779.1 - 0.079 12.7 0.0 7.3 6.3 0.0 2.7 2 0 0 2 2 2 0 N-terminal domain of fragilysin Cwf_Cwc_15 PF04889.12 PVD29779.1 - 0.23 11.2 4.4 0.54 9.9 4.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein p450 PF00067.22 PVD29780.1 - 9.7e-98 327.9 0.1 1.5e-97 327.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Wzy_C PF04932.15 PVD29781.1 - 0.34 10.5 7.1 4.3 6.9 0.8 3.3 3 0 0 3 3 3 0 O-Antigen ligase Creatinase_N_2 PF16189.5 PVD29782.1 - 2.6e-49 167.4 0.3 5.2e-49 166.4 0.3 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 PVD29782.1 - 2.8e-44 151.3 0.0 4.5e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 PVD29782.1 - 1.3e-23 82.8 0.0 4.7e-23 81.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PVD29782.1 - 1.3e-18 68.0 0.0 2.1e-13 51.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Velvet PF11754.8 PVD29782.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Velvet factor LRR_8 PF13855.6 PVD29783.1 - 5.1e-16 58.2 33.1 8.4e-08 31.9 8.0 4.2 1 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PVD29783.1 - 1.6e-10 41.0 37.8 0.00088 19.6 2.9 5.6 1 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD29783.1 - 0.00019 21.0 15.9 0.0095 15.5 1.6 3.1 2 1 1 3 3 3 3 Leucine-rich repeat TBPIP PF07106.13 PVD29784.1 - 6.8e-26 90.0 1.5 1.4e-25 89.0 0.7 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 PVD29784.1 - 7e-13 48.5 0.2 3.3e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 Leucine zipper with capping helix domain GAS PF13851.6 PVD29784.1 - 0.028 13.8 15.6 0.046 13.1 15.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 PVD29784.1 - 0.088 12.4 7.3 0.12 11.9 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Utp11 PF03998.13 PVD29784.1 - 0.13 12.2 11.4 0.18 11.7 11.4 1.2 1 0 0 1 1 1 0 Utp11 protein ER PF01133.17 PVD29784.1 - 0.16 12.0 0.9 0.41 10.7 0.2 2.1 2 0 0 2 2 2 0 Enhancer of rudimentary DivIC PF04977.15 PVD29784.1 - 0.26 11.1 13.3 0.27 11.0 3.2 2.6 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.8 PVD29784.1 - 0.58 10.5 15.6 1.1 9.6 15.6 1.5 1 0 0 1 1 1 0 YlqD protein Ribosomal_L30_N PF08079.12 PVD29784.1 - 0.82 10.0 11.8 0.16 12.3 5.5 2.5 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain DUF4972 PF16342.5 PVD29784.1 - 1 9.1 5.0 1.8 8.3 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) GrpE PF01025.19 PVD29784.1 - 1.1 8.9 11.1 3.7 7.2 11.1 1.9 1 1 0 1 1 1 0 GrpE YabA PF06156.13 PVD29784.1 - 8.2 7.1 11.5 6.6 7.4 6.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA SH2 PF00017.24 PVD29785.1 - 1.5e-12 47.5 0.0 3.4e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 SH2 domain Xan_ur_permease PF00860.20 PVD29786.1 - 1.9e-64 217.8 33.3 7.1e-64 215.9 33.3 1.7 1 1 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 PVD29787.1 - 7.9e-66 222.3 25.3 5.4e-65 219.6 25.3 1.9 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 PVD29787.1 - 5.6 7.4 14.3 2.3 8.7 0.7 3.6 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 PVD29789.1 - 4e-62 210.2 18.4 2.2e-59 201.1 16.6 2.1 1 1 1 2 2 2 2 Permease family Cytochrom_B_C PF00032.17 PVD29789.1 - 5 7.5 7.5 16 5.9 1.9 2.9 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Ferric_reduct PF01794.19 PVD29789.1 - 9.4 6.4 11.5 1.3 9.1 6.0 2.3 2 1 1 3 3 3 0 Ferric reductase like transmembrane component SSF PF00474.17 PVD29790.1 - 1.8e-27 96.3 12.7 2.8e-27 95.6 12.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 PVD29792.1 - 1.4e-11 43.9 6.9 3.1e-07 29.6 0.2 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family RIIa PF02197.17 PVD29793.1 - 0.013 15.1 0.0 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF3077 PF11275.8 PVD29793.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) SSF PF00474.17 PVD29794.1 - 3.8e-09 35.9 1.7 3.8e-09 35.9 1.7 1.3 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 PVD29795.1 - 1.7e-15 56.8 23.0 3.7e-11 42.5 4.4 4.3 2 2 2 4 4 4 4 Sodium:solute symporter family DUF2085 PF09858.9 PVD29795.1 - 0.063 13.8 0.7 0.64 10.5 0.7 2.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) DUF4539 PF15072.6 PVD29795.1 - 0.12 12.4 1.5 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) ISK_Channel PF02060.15 PVD29795.1 - 0.17 11.6 0.9 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Chlam_vir PF05475.11 PVD29795.1 - 0.57 9.9 3.1 3.7 7.3 0.2 2.6 2 0 0 2 2 2 0 Pgp3 C-terminal domain DUF4118 PF13493.6 PVD29795.1 - 1.6 8.6 16.5 1.6 8.6 0.3 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4118) SSF PF00474.17 PVD29796.1 - 1.1e-26 93.7 18.7 1.1e-26 93.7 18.7 1.6 1 1 1 2 2 2 1 Sodium:solute symporter family Lectin_C PF00059.21 PVD29796.1 - 1.9e-05 25.3 0.3 6.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain Prominin PF05478.11 PVD29796.1 - 2.8 5.8 26.0 3.6 5.4 24.6 1.9 1 1 0 1 1 1 0 Prominin DUF4407 PF14362.6 PVD29796.1 - 8.2 5.7 30.7 5.8 6.2 18.9 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) SSF PF00474.17 PVD29797.1 - 3e-38 131.7 23.1 3.7e-38 131.4 23.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family TMF_TATA_bd PF12325.8 PVD29798.1 - 0.007 16.6 3.7 0.007 16.6 3.7 3.7 3 1 2 5 5 5 1 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 PVD29798.1 - 0.026 14.3 9.1 0.12 12.1 1.8 3.8 2 1 1 3 3 3 0 Septum formation initiator DALR_1 PF05746.15 PVD29798.1 - 0.054 13.7 0.1 0.054 13.7 0.1 2.3 3 0 0 3 3 3 0 DALR anticodon binding domain FapA PF03961.13 PVD29798.1 - 0.33 9.5 2.8 0.83 8.2 2.8 1.7 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 PVD29798.1 - 0.39 11.0 9.5 0.1 12.8 3.9 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.8 PVD29798.1 - 1 9.5 9.2 0.54 10.4 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 PVD29798.1 - 5.5 7.5 7.5 1.8 9.0 0.3 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.6 PVD29798.1 - 6.3 6.1 20.7 0.049 13.0 10.9 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tubulin PF00091.25 PVD29799.1 - 1.3e-53 182.2 0.0 1.5e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD29799.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain HLH PF00010.26 PVD29800.1 - 1.9e-17 63.0 0.3 3.2e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 PVD29801.1 - 1.3e-08 34.6 0.2 1.3e-08 34.5 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29801.1 - 0.00085 18.7 0.2 0.00087 18.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Striatin PF08232.12 PVD29801.1 - 0.077 13.6 0.1 0.079 13.5 0.1 1.1 1 0 0 1 1 1 0 Striatin family Pkinase PF00069.25 PVD29802.1 - 3.4e-48 164.3 0.0 4.4e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29802.1 - 2.3e-20 73.0 0.0 2.7e-19 69.5 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD29802.1 - 0.0033 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD29802.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 PVD29802.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SatRNA_48 PF17485.2 PVD29802.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein SPATA48 PF15073.6 PVD29803.1 - 3.9e-41 140.3 0.2 6.6e-41 139.6 0.2 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Dpy19 PF10034.9 PVD29804.1 - 4e-205 682.9 15.6 4.3e-115 385.4 17.0 2.0 1 1 1 2 2 2 2 Q-cell neuroblast polarisation SAM_Exu PF18609.1 PVD29804.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Exuperantia SAM-like domain HisKA PF00512.25 PVD29805.1 - 0.066 13.3 1.1 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain LAX PF15681.5 PVD29805.1 - 0.093 11.5 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X zf-C4 PF00105.18 PVD29807.1 - 3e-22 78.8 26.8 1.9e-14 53.9 10.7 2.8 2 1 1 3 3 3 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29807.1 - 6.7e-20 71.6 0.4 1.2e-19 70.7 0.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EF-hand_6 PF13405.6 PVD29808.1 - 2.8e-06 26.8 0.0 0.00026 20.7 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 PVD29808.1 - 1.6e-05 25.3 0.1 0.0019 18.6 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD29808.1 - 0.00026 20.3 0.0 0.032 13.8 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PVD29808.1 - 0.002 17.5 0.0 0.0096 15.4 0.0 2.0 2 0 0 2 2 2 1 EF hand DNA_pol3_a_NII PF11490.8 PVD29808.1 - 0.39 10.6 0.0 0.39 10.6 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II Phosphodiest PF01663.22 PVD29809.1 - 1.6e-76 258.2 2.4 1.9e-76 258.0 2.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD29809.1 - 1.5e-08 34.4 0.2 0.00022 20.7 0.0 2.5 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 PVD29809.1 - 0.0011 18.4 0.1 0.0025 17.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 PVD29809.1 - 0.0075 16.4 0.2 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 PglZ domain DUF229 PF02995.17 PVD29809.1 - 0.16 10.5 0.1 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 PVD29810.1 - 5.7e-64 216.9 9.0 7.8e-42 144.1 3.2 2.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD29810.1 - 1.5e-09 37.7 1.4 8.5e-06 25.4 0.1 2.6 2 1 0 2 2 2 2 Sulfatase Parvo_NS1 PF01057.17 PVD29810.1 - 0.015 14.4 0.3 0.025 13.7 0.3 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Phosphodiest PF01663.22 PVD29811.1 - 2.2e-45 155.8 3.1 3.6e-38 132.1 1.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 PVD29812.1 - 4.6e-11 42.3 22.7 2.4e-08 33.3 10.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PVD29812.1 - 5 5.3 11.5 1.4 7.1 7.5 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD29813.1 - 2.7e-07 29.9 9.4 3.3e-07 29.6 9.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_r1t_holin PF16945.5 PVD29813.1 - 0.49 10.6 4.5 7.7 6.8 0.0 3.1 3 0 0 3 3 3 0 Putative lactococcus lactis phage r1t holin FtsX PF02687.21 PVD29813.1 - 5.9 7.4 10.6 14 6.3 10.6 1.7 1 1 0 1 1 1 0 FtsX-like permease family Ank_2 PF12796.7 PVD29814.1 - 7.6e-22 77.7 0.1 4.2e-11 43.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29814.1 - 4.2e-21 75.0 0.5 3.2e-09 37.1 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29814.1 - 8.5e-13 48.3 0.0 9.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD29814.1 - 6.6e-12 45.3 2.2 0.0028 18.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PVD29814.1 - 2.3e-11 42.8 0.2 0.0037 17.6 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat Enolase_C PF00113.22 PVD29815.1 - 1.4e-44 152.5 0.0 2.2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PVD29815.1 - 6.5e-15 55.5 0.5 4.8e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 Enolase, N-terminal domain SopD PF11047.8 PVD29815.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Salmonella outer protein D EzrA PF06160.12 PVD29816.1 - 6.4e-05 21.3 62.8 0.0045 15.2 14.2 3.6 1 1 1 3 3 3 3 Septation ring formation regulator, EzrA Filament PF00038.21 PVD29816.1 - 8.4e-05 22.3 59.4 0.034 13.7 44.6 3.3 1 1 1 2 2 2 2 Intermediate filament protein MscS_porin PF12795.7 PVD29816.1 - 0.00057 19.5 39.8 0.0066 16.0 16.0 3.5 3 0 0 3 3 3 2 Mechanosensitive ion channel porin domain Mod_r PF07200.13 PVD29816.1 - 0.00095 19.3 7.3 0.00095 19.3 7.3 4.9 2 1 3 5 5 4 1 Modifier of rudimentary (Mod(r)) protein RskA PF10099.9 PVD29816.1 - 0.0013 19.1 0.9 0.0032 17.8 0.1 2.0 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Baculo_PEP_C PF04513.12 PVD29816.1 - 0.0023 18.0 14.9 0.0053 16.8 3.6 3.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 PVD29816.1 - 0.0037 16.7 0.4 0.0037 16.7 0.4 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4407) SOGA PF11365.8 PVD29816.1 - 0.0078 17.3 8.5 0.0078 17.3 8.5 4.8 1 1 3 5 5 5 1 Protein SOGA GrpE PF01025.19 PVD29816.1 - 0.012 15.2 5.1 0.012 15.2 5.1 5.8 2 2 4 6 6 6 0 GrpE DUF1657 PF07870.11 PVD29816.1 - 0.029 14.3 0.9 0.029 14.3 0.9 6.5 7 0 0 7 7 7 0 Protein of unknown function (DUF1657) TPR_MLP1_2 PF07926.12 PVD29816.1 - 0.048 13.7 70.9 0.13 12.4 19.6 5.4 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein NuA4 PF09340.10 PVD29816.1 - 0.063 13.2 0.0 0.063 13.2 0.0 4.5 4 0 0 4 4 4 0 Histone acetyltransferase subunit NuA4 PRIMA1 PF16101.5 PVD29816.1 - 0.067 13.2 4.1 0.16 12.0 4.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 OmpH PF03938.14 PVD29816.1 - 0.1 12.9 54.8 0.28 11.5 14.9 4.1 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 PVD29816.1 - 0.19 12.2 0.3 0.19 12.2 0.3 7.0 5 3 1 6 6 6 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 PVD29816.1 - 0.3 11.1 45.2 0.27 11.2 16.4 4.3 4 0 0 4 4 4 0 FlxA-like protein PI3K_P85_iSH2 PF16454.5 PVD29816.1 - 0.44 10.1 57.3 0.037 13.6 22.5 3.4 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NeA_P2 PF12312.8 PVD29816.1 - 0.47 9.9 1.9 1.3 8.4 0.2 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein FPP PF05911.11 PVD29816.1 - 0.56 8.3 61.3 1.6 6.8 24.5 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 PVD29816.1 - 0.81 8.6 53.6 0.24 10.3 6.8 4.2 3 1 1 4 4 4 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 PVD29816.1 - 0.84 10.1 56.7 3 8.3 23.7 3.6 1 1 2 3 3 3 0 Fez1 Spc7 PF08317.11 PVD29816.1 - 1 8.1 61.3 0.26 10.1 21.0 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein PilJ PF13675.6 PVD29816.1 - 1.2 9.2 20.3 8.2 6.5 7.4 4.4 3 2 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3584 PF12128.8 PVD29816.1 - 2.2 5.7 56.3 5.4 4.4 31.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 PVD29816.1 - 2.6 8.2 59.8 0.5 10.6 7.3 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 PVD29816.1 - 4 6.8 67.5 1.3 8.3 18.5 3.7 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 PVD29816.1 - 6.2 7.0 67.7 0.43 10.8 4.8 5.1 1 1 4 5 5 5 0 JNK_SAPK-associated protein-1 YabA PF06156.13 PVD29816.1 - 6.6 7.4 50.6 14 6.4 13.0 5.7 2 2 1 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 PVD29816.1 - 7 6.5 50.1 0.067 13.0 6.8 5.7 3 2 2 5 5 5 0 Septum formation initiator WXG100 PF06013.12 PVD29816.1 - 7.8 6.8 23.8 2.5 8.4 0.4 6.1 4 2 0 4 4 4 0 Proteins of 100 residues with WXG DUF2043 PF09740.9 PVD29818.1 - 5.5e-33 113.8 0.0 1.8e-32 112.2 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) MYCBPAP PF14646.6 PVD29818.1 - 1.8e-05 23.9 5.4 0.059 12.3 0.0 3.1 2 1 0 3 3 3 2 MYCBP-associated protein family POTRA_1 PF08478.10 PVD29818.1 - 0.072 13.4 3.3 2.7 8.4 0.1 3.2 3 0 0 3 3 3 0 POTRA domain, FtsQ-type CK1gamma_C PF12605.8 PVD29818.1 - 0.2 12.9 1.4 0.74 11.0 1.4 2.1 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal MYCBPAP PF14646.6 PVD29819.1 - 5.6e-27 94.8 1.9 3e-25 89.1 0.0 2.4 1 1 0 2 2 2 2 MYCBP-associated protein family MYCBPAP PF14646.6 PVD29820.1 - 8.3e-23 81.0 0.0 2.7e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 MYCBP-associated protein family CBM_14 PF01607.24 PVD29821.1 - 8.7e-12 45.0 22.3 0.00031 20.8 5.3 3.9 2 1 1 3 3 3 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD29824.1 - 0.11 12.6 11.6 0.53 10.5 0.2 2.5 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD29825.1 - 0.002 18.3 10.9 0.021 15.0 4.5 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain PapJ PF14855.6 PVD29825.1 - 0.23 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Lig_chan-Glu_bd PF10613.9 PVD29826.1 - 4.3e-32 110.7 0.0 1.5e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD29826.1 - 5.5e-32 110.7 0.1 1e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD29826.1 - 2.1e-21 76.4 0.0 2.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD29826.1 - 2.3e-05 23.7 1.7 0.00013 21.2 1.7 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region Ion_trans_2 PF07885.16 PVD29826.1 - 0.00079 19.3 0.1 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 Ion channel Homeodomain PF00046.29 PVD29827.1 - 7.4e-10 38.5 0.0 9.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Homeodomain DUF2316 PF10078.9 PVD29827.1 - 0.074 13.3 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Homez PF11569.8 PVD29827.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ank_2 PF12796.7 PVD29828.1 - 6.7e-39 132.4 0.4 2.7e-12 47.1 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29828.1 - 2.6e-31 107.6 3.9 2.1e-06 28.2 0.1 6.1 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29828.1 - 4.4e-26 90.6 6.7 2.7e-09 37.1 0.1 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD29828.1 - 1.4e-23 80.4 5.0 0.00026 21.2 0.0 8.0 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 PVD29828.1 - 2.5e-23 81.4 2.9 9.4e-06 25.9 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Reprolysin PF01421.19 PVD29829.1 - 2.3e-13 50.5 0.1 1.9e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 PVD29829.1 - 6.3e-12 45.8 6.5 6.3e-12 45.8 6.5 3.1 3 1 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 PVD29829.1 - 2.9e-10 40.7 0.6 6.1e-10 39.7 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD29829.1 - 2.3e-09 37.7 2.9 2.3e-09 37.7 2.9 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD29829.1 - 6.4e-06 26.2 0.5 1.3e-05 25.1 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD29829.1 - 3.4e-05 23.6 0.4 7.7e-05 22.4 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD29829.1 - 0.054 13.3 0.2 0.076 12.8 0.2 1.3 1 0 0 1 1 1 0 Matrixin Astacin PF01400.24 PVD29829.1 - 0.055 13.1 0.1 0.055 13.1 0.1 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) PLAC PF08686.11 PVD29829.1 - 0.82 10.5 14.5 0.35 11.7 6.0 3.0 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Laminin_G_1 PF00054.23 PVD29830.1 - 1.6e-05 25.1 1.4 0.0021 18.3 0.1 2.5 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 PVD29830.1 - 0.00014 22.4 0.4 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 Laminin G domain Laminin_G_3 PF13385.6 PVD29830.1 - 0.00043 20.5 1.2 0.00043 20.5 1.2 3.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily LLGL PF08366.13 PVD29830.1 - 0.0091 16.3 0.0 12 6.3 0.0 3.3 3 0 0 3 3 3 2 LLGL2 HOCHOB PF17943.1 PVD29830.1 - 0.0094 16.7 0.6 5.2 7.8 0.1 2.5 2 0 0 2 2 2 2 Homeobox-cysteine loop-homeobox Big_5 PF13205.6 PVD29830.1 - 0.74 10.5 5.3 3.2 8.5 2.4 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain CBM_14 PF01607.24 PVD29830.1 - 3 8.1 36.5 0.15 12.2 2.3 6.3 5 2 2 7 7 7 0 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD29831.1 - 5.2e-10 39.3 13.5 7.8e-05 22.8 9.2 3.4 2 1 1 3 3 3 2 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 PVD29831.1 - 1.5 8.5 8.2 5.5 6.6 0.3 2.8 2 1 1 3 3 3 0 Viral capsid protein 91 N-terminal SDF PF00375.18 PVD29832.1 - 1.3e-126 422.7 29.0 1.7e-126 422.4 29.0 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1356 PF07092.12 PVD29833.1 - 5.3e-26 91.3 1.3 6.5e-26 91.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LRR_8 PF13855.6 PVD29834.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 PVD29835.1 - 4.3e-103 337.1 94.5 3.3e-16 58.8 2.5 10.1 4 4 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 PVD29835.1 - 3e-34 116.5 61.1 6.2e-06 26.5 0.6 11.9 5 4 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD29835.1 - 2.9e-32 111.3 0.4 7e-10 39.0 0.2 4.5 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 PVD29835.1 - 3.1e-31 107.3 137.6 1.6e-08 34.7 3.7 11.3 12 0 0 12 12 9 7 EGF-like domain LRR_9 PF14580.6 PVD29835.1 - 6.2e-25 87.7 19.8 6e-07 29.1 1.2 5.7 4 2 1 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 PVD29835.1 - 4e-22 77.4 36.8 8.1e-09 34.9 2.2 7.4 6 0 0 6 6 6 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.23 PVD29835.1 - 5.2e-22 78.5 0.0 8.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 PVD29835.1 - 4.1e-19 69.4 0.1 7.2e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 PVD29835.1 - 1.8e-15 56.9 60.7 1.4e-06 28.7 1.7 13.6 15 0 0 15 15 11 6 Human growth factor-like EGF LRRCT PF01463.24 PVD29835.1 - 1.5e-13 50.1 7.6 0.084 13.5 0.1 6.2 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain EGF_CA PF07645.15 PVD29835.1 - 0.00023 21.3 23.5 0.00072 19.7 8.1 10.7 8 2 3 11 11 9 4 Calcium-binding EGF domain LRR_1 PF00560.33 PVD29835.1 - 0.0006 20.0 47.3 4.8 8.1 1.4 15.4 16 4 0 16 16 14 3 Leucine Rich Repeat EGF_2 PF07974.13 PVD29835.1 - 0.0051 17.1 11.0 0.0051 17.1 11.0 12.2 13 1 0 13 13 11 5 EGF-like domain COMPASS-Shg1 PF05205.12 PVD29836.1 - 3.9e-20 72.5 0.2 3.9e-20 72.5 0.2 3.8 4 1 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component shg1 Ly49 PF08391.10 PVD29836.1 - 1.4 9.3 9.9 0.16 12.3 2.8 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Mito_carr PF00153.27 PVD29837.1 - 2.2e-65 216.6 2.1 1.7e-21 75.9 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PVD29837.1 - 0.069 12.3 0.5 6.2 5.9 0.1 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease KH_1 PF00013.29 PVD29838.1 - 0.00049 19.9 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 KH domain Phosphodiest PF01663.22 PVD29839.1 - 1.6e-70 238.5 1.7 1.9e-70 238.3 1.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PVD29839.1 - 9.2e-07 28.5 0.3 0.02 14.3 0.0 2.2 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 PVD29839.1 - 0.00078 18.9 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 PVD29840.1 - 3e-63 214.6 0.3 3.7e-63 214.3 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 PVD29840.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Ig_3 PF13927.6 PVD29842.1 - 9.2e-15 55.0 0.0 2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD29842.1 - 8.8e-13 48.1 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD29842.1 - 2.5e-09 37.3 0.0 6.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD29842.1 - 2.6e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD29842.1 - 0.0006 20.0 0.1 0.15 12.2 0.0 2.6 1 1 1 2 2 2 1 Immunoglobulin V-set domain EGF_2 PF07974.13 PVD29842.1 - 0.00094 19.5 11.1 0.00094 19.5 11.1 4.5 5 1 0 5 5 5 1 EGF-like domain hEGF PF12661.7 PVD29842.1 - 0.0045 17.6 9.0 0.0045 17.6 9.0 5.5 6 0 0 6 6 6 1 Human growth factor-like EGF C2-set_2 PF08205.12 PVD29842.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain EGF PF00008.27 PVD29842.1 - 2.6 8.4 20.3 0.03 14.6 8.1 4.0 3 1 1 4 4 4 0 EGF-like domain PARP PF00644.20 PVD29843.1 - 2.3e-24 86.1 0.0 6.6e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD29843.1 - 6.1e-18 65.0 0.3 1.6e-17 63.6 0.1 1.9 2 0 0 2 2 2 1 Macro domain WWE PF02825.20 PVD29843.1 - 0.00021 21.8 0.3 0.00091 19.8 0.3 2.2 1 0 0 1 1 1 1 WWE domain NID PF07292.13 PVD29843.1 - 0.48 11.1 2.1 14 6.4 0.0 3.7 3 1 0 3 3 3 0 Nmi/IFP 35 domain (NID) Macro PF01661.21 PVD29844.1 - 9.2e-19 67.6 0.0 2.2e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Macro domain PARP PF00644.20 PVD29844.1 - 4.2e-18 65.6 1.4 7.5e-09 35.5 0.3 3.3 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 PVD29844.1 - 0.00019 21.2 0.2 0.12 12.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD29844.1 - 0.0049 16.7 0.0 0.26 11.2 0.0 2.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PVD29844.1 - 0.0052 16.8 0.9 2.1 8.4 0.0 3.7 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif NID PF07292.13 PVD29844.1 - 0.042 14.5 3.8 11 6.8 0.0 4.9 6 0 0 6 6 6 0 Nmi/IFP 35 domain (NID) WWE PF02825.20 PVD29844.1 - 0.12 13.0 0.1 0.67 10.6 0.1 2.4 2 0 0 2 2 2 0 WWE domain PARP PF00644.20 PVD29845.1 - 3.6e-25 88.7 1.5 1.1e-24 87.1 1.5 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD29845.1 - 1e-17 64.3 0.4 3.5e-17 62.6 0.0 2.3 2 0 0 2 2 2 1 Macro domain NID PF07292.13 PVD29845.1 - 1.4e-14 54.5 7.0 0.18 12.5 0.0 8.6 7 2 0 7 7 7 4 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 PVD29845.1 - 1.4e-14 53.6 3.2 0.019 14.8 0.0 6.6 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWE PF02825.20 PVD29845.1 - 0.00041 20.9 0.7 0.0015 19.1 0.7 2.0 1 0 0 1 1 1 1 WWE domain RRM_occluded PF16842.5 PVD29845.1 - 0.0084 16.0 0.0 12 5.8 0.0 4.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif Exotox-A_cataly PF09009.10 PVD29845.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Exotoxin A catalytic Tox-ART-HYD1 PF15633.6 PVD29845.1 - 0.12 13.1 0.0 0.59 10.8 0.0 2.3 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase DUF1522 PF07482.11 PVD29845.1 - 0.16 12.3 1.8 0.19 12.0 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) UCH_1 PF13423.6 PVD29846.1 - 3.3e-75 253.7 4.2 3.3e-75 253.7 4.2 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 PVD29846.1 - 1.3e-18 68.1 0.0 3.3e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Exonuclease zf-C2H2 PF00096.26 PVD29846.1 - 2.2e-12 46.7 47.8 0.0012 19.2 0.6 6.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD29846.1 - 8.9e-10 38.6 31.9 0.00038 20.8 0.3 6.0 5 0 0 5 5 5 4 Zinc-finger double domain UCH PF00443.29 PVD29846.1 - 9.2e-07 28.6 0.6 1.3e-05 24.8 0.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase eIF2A PF08662.11 PVD29846.1 - 5.3e-05 23.2 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A zf-C2H2_4 PF13894.6 PVD29846.1 - 0.00011 22.8 54.1 0.041 14.7 0.6 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-CCCH_2 PF14608.6 PVD29846.1 - 0.041 14.4 2.1 0.14 12.7 2.1 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C2H2_11 PF16622.5 PVD29846.1 - 0.52 10.1 43.8 0.0075 16.0 3.5 5.8 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-CCHH PF10283.9 PVD29846.1 - 1.7 8.7 6.3 4.3 7.4 6.3 1.7 1 0 0 1 1 1 0 PBZ domain Defensin_4 PF07936.12 PVD29847.1 - 2.1 8.3 5.4 2.2 8.3 0.2 2.3 1 1 1 2 2 2 0 Potassium-channel blocking toxin Citrate_bind PF16114.5 PVD29848.1 - 3.6e-92 306.7 0.1 6.4e-92 305.9 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 PVD29848.1 - 3.4e-24 85.6 0.0 2.1e-21 76.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 PVD29848.1 - 5.9e-17 61.9 0.1 1.3e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 PVD29848.1 - 9.8e-13 48.6 0.0 2.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 PVD29848.1 - 9.3e-12 44.9 0.2 1.8e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 PVD29848.1 - 1.1e-05 25.2 0.1 4.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain NAD_binding_3 PF03447.16 PVD29848.1 - 0.12 13.1 0.1 9.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 PVD29848.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TM2 PF05154.16 PVD29849.1 - 5.2e-14 52.3 8.6 8e-14 51.7 8.6 1.3 1 0 0 1 1 1 1 TM2 domain TRAM_LAG1_CLN8 PF03798.16 PVD29850.1 - 4.4e-36 124.5 15.5 5.6e-36 124.1 15.5 1.1 1 0 0 1 1 1 1 TLC domain FAM176 PF14851.6 PVD29850.1 - 0.039 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 FAM176 family DAN PF03045.15 PVD29852.1 - 0.0012 18.9 3.4 0.0016 18.4 3.4 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 PVD29852.1 - 0.01 16.1 6.1 0.013 15.7 6.1 1.2 1 0 0 1 1 1 0 Cystine-knot domain Ank_4 PF13637.6 PVD29853.1 - 7.1e-25 87.1 3.1 3.1e-11 43.6 0.1 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD29853.1 - 9.8e-24 83.8 10.3 1.4e-08 35.2 0.2 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD29853.1 - 1.4e-22 79.0 6.5 6.3e-08 32.7 0.5 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PVD29853.1 - 8.2e-22 75.0 1.3 1e-06 28.5 0.3 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PVD29853.1 - 1.8e-16 60.0 2.1 3e-07 30.6 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Pkinase PF00069.25 PVD29855.1 - 2.1e-57 194.5 0.0 6.2e-57 193.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29855.1 - 1.8e-38 132.4 0.5 5.8e-38 130.6 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 PVD29855.1 - 1.6e-06 28.3 0.0 2.2e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD29855.1 - 1.8e-06 27.5 0.1 7.3e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD29855.1 - 2.9e-06 26.3 0.1 1e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD29855.1 - 7.7e-06 25.1 0.2 7.7e-06 25.1 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 PVD29855.1 - 9.4e-06 25.3 0.1 2.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Arm PF00514.23 PVD29855.1 - 3e-05 23.9 6.4 0.011 15.8 0.1 4.9 4 1 2 6 6 6 2 Armadillo/beta-catenin-like repeat Choline_kinase PF01633.20 PVD29855.1 - 0.094 12.3 0.7 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 PVD29856.1 - 1.2e-12 47.4 0.0 2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MGC-24 PF05283.11 PVD29859.1 - 0.00041 20.8 8.3 0.00041 20.8 8.3 3.1 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.6 PVD29859.1 - 0.014 15.5 4.9 0.036 14.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 PVD29859.1 - 0.039 13.8 10.3 0.093 12.6 0.0 2.1 2 0 0 2 2 2 0 Rifin PSI PF01437.25 PVD29859.1 - 0.57 10.8 16.8 0.23 12.0 13.8 1.9 2 0 0 2 2 2 0 Plexin repeat SAP130_C PF16014.5 PVD29859.1 - 2.6 7.1 11.6 4.3 6.3 11.6 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Atrophin-1 PF03154.15 PVD29859.1 - 4.7 5.4 14.7 7.9 4.6 14.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family HalOD1 PF18545.1 PVD29860.1 - 0.012 15.9 0.0 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Halobacterial output domain 1 Pox_I5 PF04713.12 PVD29860.1 - 0.074 13.1 0.5 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Poxvirus protein I5 DUF3285 PF11688.8 PVD29860.1 - 0.093 12.7 6.3 0.095 12.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Calc_CGRP_IAPP PF00214.19 PVD29860.1 - 0.15 12.4 0.3 1.3 9.4 0.1 2.1 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family Integrin_alpha2 PF08441.12 PVD29861.1 - 9.8e-71 239.0 0.0 1.3e-70 238.6 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 PVD29861.1 - 6.7e-09 35.7 12.7 5.6e-06 26.4 0.3 3.6 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 PVD29861.1 - 6.4e-06 26.7 8.0 0.0041 17.7 0.3 3.3 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 PVD29861.1 - 0.02 14.8 1.5 0.056 13.5 1.5 1.8 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Syndecan PF01034.20 PVD29861.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 PVD29863.1 - 3.5e-53 180.6 0.0 2.2e-50 171.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29863.1 - 1.8e-24 86.4 0.0 5.1e-24 85.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD29863.1 - 0.0002 20.8 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD29863.1 - 0.023 13.7 0.0 0.023 13.7 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain PCI PF01399.27 PVD29863.1 - 0.097 13.2 0.3 0.22 12.0 0.3 1.5 1 0 0 1 1 1 0 PCI domain Pkinase_fungal PF17667.1 PVD29863.1 - 0.18 10.5 0.0 0.18 10.5 0.0 3.1 2 1 0 2 2 2 0 Fungal protein kinase Inositol_P PF00459.25 PVD29864.1 - 5.7e-31 108.0 0.4 1.9e-28 99.8 0.1 2.0 2 0 0 2 2 2 2 Inositol monophosphatase family Ras PF00071.22 PVD29865.1 - 8.1e-31 106.8 2.9 9.4e-26 90.3 0.2 2.4 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PVD29865.1 - 1.6e-07 31.6 0.5 0.0091 16.2 0.1 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD29865.1 - 1.9e-05 24.7 2.0 0.038 13.9 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 PVD29865.1 - 0.0063 16.0 0.1 0.045 13.2 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Med1 PF10744.9 PVD29866.1 - 4.7e-49 167.6 0.2 1.2e-48 166.2 0.2 1.8 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 zf-DBF PF07535.12 PVD29867.1 - 1.5e-14 53.8 2.8 1.5e-14 53.8 2.8 2.3 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.26 PVD29867.1 - 1e-05 25.8 0.0 4.2e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain MAM PF00629.23 PVD29867.1 - 0.028 14.4 1.6 0.083 12.8 1.6 1.8 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu DUF4208 PF13907.6 PVD29867.1 - 0.56 10.7 3.6 33 5.0 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) WD40 PF00400.32 PVD29868.1 - 1.1e-05 26.0 9.5 0.044 14.7 0.1 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat PAP2 PF01569.21 PVD29869.1 - 2.3e-13 50.1 2.0 2.3e-13 50.1 2.0 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 PVD29869.1 - 0.00012 21.8 8.3 0.00012 21.8 8.3 2.6 2 1 0 2 2 2 1 PAP2 superfamily PsbI PF02532.14 PVD29869.1 - 7 6.7 8.9 1.1 9.2 1.2 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) RskA PF10099.9 PVD29870.1 - 0.089 13.1 0.2 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Pkinase PF00069.25 PVD29871.1 - 2.9e-66 223.5 0.0 4.5e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD29871.1 - 5.2e-34 117.7 0.0 8.4e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 PVD29871.1 - 9.4e-21 74.3 1.4 2.3e-20 73.0 1.4 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 PVD29871.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD29871.1 - 2.6e-05 23.2 0.0 0.00014 20.7 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 PVD29871.1 - 0.017 14.7 0.6 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PVD29871.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.21 PVD29872.1 - 8.7e-78 261.3 0.0 2e-77 260.1 0.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29872.1 - 7e-08 32.2 9.2 2.4e-05 23.9 6.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4374 PF14298.6 PVD29872.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) Paramyxo_C PF01692.18 PVD29872.1 - 2.7 7.3 4.4 0.64 9.4 0.4 1.8 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C DEAD PF00270.29 PVD29875.1 - 2.1e-42 144.9 0.2 6.5e-42 143.3 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD29875.1 - 6.2e-32 110.2 0.0 2e-31 108.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD29875.1 - 5.5e-07 29.7 0.0 1.6e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PVD29875.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain HEM4 PF02602.15 PVD29876.1 - 1.9e-40 138.7 0.0 3.2e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD 7tm_1 PF00001.21 PVD29881.1 - 3.3e-12 46.3 13.9 2.9e-09 36.7 5.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) EcoRI_methylase PF13651.6 PVD29881.1 - 0.0045 16.3 0.0 0.0065 15.7 0.0 1.1 1 0 0 1 1 1 1 Adenine-specific methyltransferase EcoRI 7TM_GPCR_Srx PF10328.9 PVD29881.1 - 0.079 12.6 9.8 0.043 13.5 6.6 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-HC5HC2H_2 PF13832.6 PVD29882.1 - 1e-28 99.7 12.3 1e-28 99.7 12.3 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PVD29882.1 - 4e-20 71.9 9.9 4e-20 71.9 9.9 3.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 PVD29882.1 - 9.8e-14 50.6 5.3 9.8e-14 50.6 5.3 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PVD29882.1 - 1.8e-08 34.1 10.0 1.8e-08 34.1 10.0 3.4 3 1 0 3 3 3 1 PHD-finger DivIC PF04977.15 PVD29882.1 - 0.57 10.0 3.8 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator PGA2 PF07543.12 PVD29882.1 - 0.8 9.7 7.7 0.035 14.1 2.0 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Thiolase_N PF00108.23 PVD29883.1 - 3.4e-70 236.4 2.4 4.4e-70 236.0 2.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD29883.1 - 6.3e-47 158.3 0.2 1.5e-46 157.0 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PVD29883.1 - 6.1e-05 22.7 0.3 0.0002 21.0 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 PVD29883.1 - 0.00094 19.0 0.4 1 9.2 0.1 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 PVD29883.1 - 0.029 14.5 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RNA_polI_A34 PF08208.11 PVD29883.1 - 0.044 13.9 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ank_2 PF12796.7 PVD29884.1 - 2.1e-22 79.5 1.6 4.3e-14 52.9 0.2 2.9 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD29884.1 - 8.8e-22 76.9 2.6 1.1e-08 35.1 0.1 4.1 3 1 2 5 5 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD29884.1 - 2.4e-19 69.5 3.7 8.1e-14 51.8 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD29884.1 - 1.5e-16 60.0 0.5 0.00022 21.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PVD29884.1 - 1.2e-12 46.8 0.7 0.019 15.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Filament PF00038.21 PVD29884.1 - 0.011 15.3 14.6 0.015 14.9 3.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein FAM76 PF16046.5 PVD29884.1 - 0.034 13.5 14.0 0.032 13.6 2.9 2.3 1 1 1 2 2 2 0 FAM76 protein DUF1192 PF06698.11 PVD29884.1 - 0.034 14.2 2.7 0.08 13.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.7 PVD29884.1 - 0.036 14.2 19.5 0.45 10.7 8.4 2.4 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.8 PVD29884.1 - 0.13 12.3 18.9 0.61 10.1 3.3 3.8 2 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 PVD29884.1 - 0.15 12.4 18.9 0.27 11.6 2.6 3.9 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF3584 PF12128.8 PVD29884.1 - 1.7 6.1 14.8 2.4 5.6 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 PVD29884.1 - 2 8.4 11.4 16 5.4 0.1 4.7 4 1 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 PVD29884.1 - 2.5 8.5 14.6 0.31 11.4 0.9 3.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 PVD29884.1 - 3 8.0 19.9 0.69 10.1 10.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 PVD29884.1 - 3.4 7.4 15.8 6.2 6.6 4.4 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4140 PF13600.6 PVD29884.1 - 3.5 8.1 5.7 42 4.7 1.1 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 PVD29884.1 - 3.7 7.7 12.7 4.5 7.5 3.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 PVD29884.1 - 4.1 7.4 8.1 2.8 8.0 2.6 2.4 2 0 0 2 2 2 0 FlxA-like protein Nnf1 PF03980.14 PVD29884.1 - 4.4 7.7 10.8 11 6.4 0.8 2.8 2 1 0 2 2 2 0 Nnf1 DUF4407 PF14362.6 PVD29884.1 - 4.4 6.6 7.7 9 5.5 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 PVD29884.1 - 4.9 7.6 16.2 5.6 7.4 4.3 2.5 1 1 1 2 2 2 0 Fez1 DivIC PF04977.15 PVD29884.1 - 5.5 6.8 15.8 0.97 9.2 1.5 3.5 3 1 0 3 3 3 0 Septum formation initiator Ldr_toxin PF13940.6 PVD29886.1 - 3.1 7.9 5.4 0.69 10.0 1.5 2.0 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system 7tm_1 PF00001.21 PVD29887.1 - 8.8e-20 71.1 13.2 1.2e-19 70.7 13.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29887.1 - 3.5e-05 23.3 12.3 0.0087 15.4 0.0 3.0 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Wzy_C PF04932.15 PVD29887.1 - 7.8e-05 22.4 4.0 0.093 12.4 0.2 2.4 2 0 0 2 2 2 2 O-Antigen ligase Srg PF02118.21 PVD29887.1 - 0.00014 21.6 9.1 0.00014 21.6 9.1 2.0 2 0 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 PVD29887.1 - 0.00047 19.9 14.5 0.00097 18.8 14.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 PVD29887.1 - 0.012 15.1 16.7 0.021 14.4 16.7 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.15 PVD29887.1 - 0.013 15.5 2.6 0.013 15.5 2.6 2.6 2 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Cytochrom_C_asm PF01578.20 PVD29887.1 - 4.5 7.0 14.9 55 3.4 14.6 2.8 1 1 0 1 1 1 0 Cytochrome C assembly protein 7tm_1 PF00001.21 PVD29888.1 - 1.2e-19 70.7 18.9 1.4e-19 70.5 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD29888.1 - 1.5e-05 24.8 13.2 1.5e-05 24.8 13.2 2.0 2 0 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srw PF10324.9 PVD29888.1 - 6.7e-05 22.3 23.7 0.11 11.7 23.7 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD29888.1 - 0.001 18.7 21.3 0.0036 17.0 20.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD29888.1 - 0.0047 16.9 1.3 0.0047 16.9 1.3 2.7 2 2 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa Wzy_C PF04932.15 PVD29888.1 - 0.011 15.3 13.8 0.099 12.3 0.1 3.0 2 1 0 2 2 2 0 O-Antigen ligase Phage_holin_3_6 PF07332.11 PVD29888.1 - 1.9 8.5 18.9 0.18 11.9 0.3 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III T4SS_CagC PF16943.5 PVD29888.1 - 6.4 7.0 6.9 2.7 8.2 1.1 2.7 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system 7tm_1 PF00001.21 PVD29889.1 - 8.1e-33 113.9 48.6 1.2e-18 67.4 19.1 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29889.1 - 0.0066 15.8 33.2 1.3 8.3 15.7 4.2 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw PsiB PF06290.11 PVD29889.1 - 0.036 13.5 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) DUF1478 PF07349.11 PVD29889.1 - 0.11 12.4 7.0 0.28 11.0 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1478) Calcyon PF06387.11 PVD29889.1 - 0.82 9.6 3.9 3.9 7.4 2.3 2.7 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) 7TM_GPCR_Srsx PF10320.9 PVD29889.1 - 1.7 8.0 47.5 2 7.7 18.1 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD29890.1 - 7.4e-07 28.7 4.1 7.4e-07 28.7 4.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD29890.1 - 0.0021 17.4 6.0 0.0021 17.4 6.0 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Phage_holin_3_6 PF07332.11 PVD29890.1 - 0.14 12.2 11.5 1.1 9.3 5.6 2.6 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DHHC PF01529.20 PVD29890.1 - 0.41 10.7 9.9 0.049 13.7 2.7 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase AIMP2_LysRS_bd PF16780.5 PVD29890.1 - 0.52 10.1 2.3 1.9 8.3 0.2 2.3 1 1 1 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain 7tm_1 PF00001.21 PVD29891.1 - 1.1e-19 70.8 18.0 1.4e-19 70.4 18.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29891.1 - 2.3e-10 40.2 13.4 9.5e-09 35.0 4.5 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw STE3 PF02076.15 PVD29891.1 - 1.5e-05 24.4 4.3 1.5e-05 24.4 4.3 1.9 2 1 0 2 2 2 1 Pheromone A receptor 7TM_GPCR_Srx PF10328.9 PVD29891.1 - 0.00063 19.4 16.6 0.0013 18.5 16.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DHHC PF01529.20 PVD29891.1 - 0.012 15.8 3.4 0.012 15.8 3.4 2.5 2 1 1 3 3 3 0 DHHC palmitoyltransferase Acyl_transf_3 PF01757.22 PVD29891.1 - 0.012 14.7 5.0 0.014 14.5 5.0 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF2070 PF09843.9 PVD29891.1 - 0.017 13.4 3.7 0.017 13.5 2.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3671 PF12420.8 PVD29891.1 - 0.054 13.6 4.2 0.066 13.3 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function 7TM_GPCR_Srsx PF10320.9 PVD29891.1 - 0.063 12.6 15.8 0.12 11.7 15.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx TraS PF10624.9 PVD29891.1 - 0.19 11.7 6.3 0.096 12.6 4.1 1.7 1 1 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF898 PF05987.13 PVD29891.1 - 1.2 8.2 11.9 3 6.8 11.8 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.6 PVD29891.1 - 1.4 8.5 6.3 0.14 11.8 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Chromate_transp PF02417.15 PVD29891.1 - 2.3 8.3 10.4 8.5 6.5 10.4 2.0 1 1 0 1 1 1 0 Chromate transporter Serpentine_r_xa PF03383.15 PVD29891.1 - 2.5 8.0 16.0 0.045 13.7 3.0 2.3 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Yip1 PF04893.17 PVD29891.1 - 5.5 6.7 16.8 12 5.6 3.3 2.7 1 1 1 2 2 2 0 Yip1 domain DUF456 PF04306.13 PVD29891.1 - 6.3 7.1 11.8 0.26 11.6 4.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF456) DUF4381 PF14316.6 PVD29891.1 - 7.9 6.7 5.9 0.91 9.8 0.3 2.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4381) 7tm_1 PF00001.21 PVD29892.1 - 9.6e-17 61.2 24.1 1.2e-16 60.9 24.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29892.1 - 1.4e-10 41.0 19.3 4.4e-09 36.0 19.3 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD29892.1 - 2.8e-07 30.2 23.9 5.4e-07 29.3 23.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD29893.1 - 2.1e-15 56.8 29.0 2.6e-15 56.5 29.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29893.1 - 4.9e-10 39.2 21.1 2.7e-08 33.5 21.1 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD29893.1 - 7e-07 28.9 24.8 9.1e-07 28.5 24.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD29894.1 - 1e-14 54.5 21.9 1.3e-14 54.2 21.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29894.1 - 1.3e-08 34.5 22.0 8.9e-07 28.5 22.0 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD29894.1 - 1.5e-07 31.1 22.5 3.5e-07 29.9 22.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF973 PF06157.11 PVD29894.1 - 0.0038 16.3 1.3 0.0038 16.3 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF973) CcmH PF03918.14 PVD29894.1 - 0.091 12.1 0.4 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein TraS PF10624.9 PVD29894.1 - 0.42 10.5 5.3 0.11 12.4 1.3 2.0 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS 7tm_1 PF00001.21 PVD29895.1 - 3.1e-16 59.5 21.5 4e-16 59.1 21.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29895.1 - 1.8e-08 34.1 16.7 1.6e-06 27.7 16.7 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4064 PF13273.6 PVD29895.1 - 0.066 13.5 0.2 0.066 13.5 0.2 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.21 PVD29896.1 - 9.6e-17 61.2 23.7 1.1e-16 60.9 23.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29896.1 - 1.1e-10 41.3 21.3 6.5e-09 35.5 21.3 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD29896.1 - 4.9e-07 29.4 27.0 2.1e-06 27.3 26.8 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YajC PF02699.15 PVD29896.1 - 0.062 13.2 0.4 0.22 11.4 0.4 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit SIT PF15330.6 PVD29896.1 - 0.11 13.0 0.5 4.6 7.7 0.0 2.7 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF898 PF05987.13 PVD29896.1 - 4.2 6.3 14.1 0.015 14.3 1.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) 7tm_1 PF00001.21 PVD29897.1 - 3.2e-09 36.5 10.0 3.7e-09 36.3 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD29898.1 - 1.3e-19 70.6 11.7 1.6e-19 70.3 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29898.1 - 7.6e-09 35.3 9.8 9.5e-09 35.0 9.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD29898.1 - 3e-06 27.1 10.4 4.6e-06 26.4 10.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD29898.1 - 7.2e-06 25.5 10.8 0.00034 20.0 10.8 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw YajC PF02699.15 PVD29898.1 - 0.044 13.7 0.4 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit BatD PF13584.6 PVD29898.1 - 0.7 8.6 1.6 0.65 8.7 0.1 1.6 1 1 1 2 2 2 0 Oxygen tolerance 7tm_1 PF00001.21 PVD29899.1 - 4e-13 49.3 26.5 5.2e-13 48.9 26.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29899.1 - 5.7e-06 25.9 19.7 5.7e-06 25.9 19.7 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD29899.1 - 1.5e-05 24.5 19.1 0.0011 18.3 19.1 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD29900.1 - 3.1e-15 56.2 24.5 4e-15 55.9 24.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD29900.1 - 6.6e-10 38.8 21.8 5.7e-09 35.7 21.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD29900.1 - 7.8e-06 25.5 26.6 2.9e-05 23.6 26.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YajC PF02699.15 PVD29900.1 - 0.23 11.3 0.9 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit 7TM_GPCR_Srw PF10324.9 PVD29901.1 - 7.4e-05 22.2 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF456 PF04306.13 PVD29901.1 - 0.00023 21.4 0.3 0.00031 21.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) 7tm_1 PF00001.21 PVD29901.1 - 0.0023 17.3 0.2 0.0026 17.1 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 PVD29901.1 - 0.0052 16.0 0.9 0.0069 15.6 0.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 PVD29902.1 - 2.4e-18 66.4 22.0 3.2e-18 66.0 22.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF456 PF04306.13 PVD29902.1 - 0.0024 18.2 0.4 0.0024 18.2 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF456) 7TM_GPCR_Srx PF10328.9 PVD29902.1 - 0.0032 17.2 15.2 0.0032 17.2 15.2 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD29902.1 - 0.019 14.3 24.8 0.06 12.7 24.8 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx SOCS PF12610.8 PVD29902.1 - 0.024 15.0 1.1 0.15 12.5 0.0 2.5 3 0 0 3 3 3 0 Suppressor of cytokine signalling PRIMA1 PF16101.5 PVD29902.1 - 0.069 13.2 0.1 0.069 13.2 0.1 2.3 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 CbtB PF09489.10 PVD29902.1 - 0.77 9.9 8.7 3.4 7.8 0.3 3.5 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF4064 PF13273.6 PVD29902.1 - 3.3 8.0 9.1 3.2 8.1 2.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.21 PVD29903.1 - 1e-19 70.9 24.5 1.2e-19 70.6 24.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29903.1 - 1.3e-05 24.7 24.5 2.6e-05 23.8 24.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF456 PF04306.13 PVD29903.1 - 0.00047 20.5 1.4 0.00047 20.5 1.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF456) 7TM_GPCR_Srx PF10328.9 PVD29903.1 - 0.0052 16.5 13.8 0.0052 16.5 13.8 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PRIMA1 PF16101.5 PVD29903.1 - 8 6.5 7.1 0.47 10.5 0.2 2.4 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Integrin_alpha2 PF08441.12 PVD29905.1 - 1.6e-42 146.0 2.6 3.1e-42 145.1 2.6 1.5 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 PVD29905.1 - 8.6e-14 51.4 8.7 2.9e-09 36.9 0.1 3.5 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 PVD29905.1 - 3.2e-05 24.4 1.1 0.00077 20.0 0.5 3.1 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha2 PF08441.12 PVD29906.1 - 2.7e-36 125.5 0.1 3.8e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 PVD29906.1 - 3.7e-15 55.7 15.4 5.5e-10 39.2 0.5 3.8 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 PVD29906.1 - 9.6e-06 26.1 1.8 0.00061 20.3 1.4 3.5 3 1 2 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Herpes_U47 PF05467.11 PVD29906.1 - 0.23 9.6 6.3 3.1 5.8 2.2 2.1 2 0 0 2 2 2 0 Herpesvirus glycoprotein U47 Integrin_alpha2 PF08441.12 PVD29907.1 - 1.4e-17 63.7 0.2 2e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 PVD29907.1 - 4.5e-14 52.3 6.2 2.6e-07 30.6 0.0 3.5 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 PVD29907.1 - 8e-07 29.6 0.2 0.00012 22.6 0.2 3.4 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha2 PF08441.12 PVD29908.1 - 1.9e-53 182.0 4.1 2.7e-48 165.0 1.1 2.2 2 0 0 2 2 2 2 Integrin alpha FG-GAP PF01839.23 PVD29908.1 - 3.8e-13 49.3 15.3 6.9e-08 32.5 0.2 3.9 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 PVD29908.1 - 0.0003 21.3 7.6 0.00046 20.7 1.1 3.8 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 PVD29908.1 - 0.033 14.4 11.1 1.5 9.2 1.4 4.2 4 0 0 4 4 4 0 FG-GAP repeat Collectrin PF16959.5 PVD29908.1 - 0.47 10.2 1.8 1.3 8.8 1.8 1.7 1 0 0 1 1 1 0 Renal amino acid transporter Integrin_alpha2 PF08441.12 PVD29910.1 - 4.2e-14 52.3 0.2 8.6e-13 48.0 0.0 2.2 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 PVD29910.1 - 8.3e-11 41.8 9.3 3.4e-08 33.5 0.3 3.8 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 PVD29910.1 - 0.00068 20.2 0.0 0.15 12.7 0.0 3.4 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Thr_synth_N PF14821.6 PVD29911.1 - 3.9e-20 71.8 0.1 9e-19 67.5 0.0 2.8 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.25 PVD29911.1 - 1e-13 51.4 0.0 5.2e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBFB_NFYA PF02045.15 PVD29911.1 - 3.8e-13 49.8 3.2 8e-13 48.8 3.2 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Fe-ADH_2 PF13685.6 PVD29911.1 - 0.053 13.2 0.7 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Rax2 PF12768.7 PVD29911.1 - 0.065 12.7 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity LSM PF01423.22 PVD29912.1 - 5.3e-22 77.3 0.1 5.8e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain ENTH PF01417.20 PVD29914.1 - 6.8e-46 155.4 0.1 1.1e-45 154.7 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PVD29914.1 - 4.8e-06 25.8 0.0 7.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain WD40 PF00400.32 PVD29915.1 - 1.6e-32 111.0 12.4 0.0027 18.5 0.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD29915.1 - 2.4e-16 59.8 0.0 0.0018 18.6 0.0 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD29915.1 - 3.2e-09 36.9 0.0 0.041 13.7 0.0 5.2 2 2 1 5 5 5 4 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 PVD29915.1 - 0.0034 16.5 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Lactonase PF10282.9 PVD29915.1 - 0.034 13.4 0.0 0.23 10.7 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller PP_kinase_C PF13090.6 PVD29915.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Frtz PF11768.8 PVD29915.1 - 0.11 10.9 0.1 5.4 5.2 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz TTL PF03133.15 PVD29916.1 - 1.7e-96 322.8 0.4 3.5e-96 321.8 0.4 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD29916.1 - 1.3e-05 24.6 2.4 0.0015 17.8 0.0 3.0 2 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD29916.1 - 0.025 13.9 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 PVD29916.1 - 0.074 13.1 0.1 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain zf-B_box PF00643.24 PVD29917.1 - 6.1e-11 42.3 8.9 6.1e-11 42.3 8.9 4.8 4 1 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD29917.1 - 1.7e-09 37.5 7.5 1.7e-09 37.5 7.5 3.9 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD29917.1 - 1.5e-08 34.4 8.6 1.5e-08 34.4 8.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD29917.1 - 4.3e-08 32.9 10.7 4.3e-08 32.9 10.7 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD29917.1 - 4.5e-08 32.9 7.8 4.5e-08 32.9 7.8 3.4 2 1 1 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD29917.1 - 1.2e-07 31.4 9.5 1.2e-07 31.4 9.5 4.1 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD29917.1 - 1.7e-07 31.5 9.6 1.7e-07 31.5 9.6 3.9 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD29917.1 - 2e-07 31.0 9.5 2e-07 31.0 9.5 3.9 3 2 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD29917.1 - 0.00024 20.9 10.4 0.00024 20.9 10.4 3.9 4 1 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD29917.1 - 0.0056 16.5 6.9 0.0056 16.5 6.9 3.8 3 2 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 PVD29917.1 - 0.0077 16.1 4.8 0.0077 16.1 4.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Exonuc_VII_L PF02601.15 PVD29917.1 - 0.019 14.5 1.4 0.027 14.0 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 PVD29917.1 - 0.28 11.8 5.0 0.7 10.5 5.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PriA_C PF18074.1 PVD29917.1 - 0.87 10.4 2.3 2.4 9.0 0.3 2.2 1 1 0 2 2 2 0 Primosomal protein N C-terminal domain TPH PF13868.6 PVD29918.1 - 5.4e-14 51.5 115.5 5.4e-14 51.5 115.5 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Put_Phosphatase PF06888.12 PVD29919.1 - 3.8e-74 249.0 0.0 4.3e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 PVD29919.1 - 4.8e-08 33.6 0.5 1.4e-07 32.1 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD29919.1 - 0.00036 20.9 0.0 0.041 14.2 0.0 2.6 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PVD29919.1 - 0.0033 17.5 0.5 13 5.8 0.0 3.1 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase MobB PF03205.14 PVD29919.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 2-Hacid_dh_C PF02826.19 PVD29920.1 - 2.7e-57 193.0 0.0 4.6e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD29920.1 - 4.3e-40 136.5 0.1 6.3e-40 135.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PVD29920.1 - 0.01 16.0 0.1 0.045 13.9 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 PVD29920.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 PVD29920.1 - 0.19 12.3 2.0 17 6.1 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Gp_dh_N PF00044.24 PVD29920.1 - 0.28 11.5 1.2 4.1 7.8 0.3 2.5 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ZU5 PF00791.20 PVD29921.1 - 2.4e-11 43.8 0.0 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 ZU5 domain TNFR_c6 PF00020.18 PVD29921.1 - 0.00029 21.2 5.8 0.00029 21.2 5.8 2.5 2 0 0 2 2 2 1 TNFR/NGFR cysteine-rich region Homeodomain PF00046.29 PVD29922.1 - 2.6e-11 43.2 0.8 4.4e-11 42.4 0.8 1.3 1 0 0 1 1 1 1 Homeodomain FAM176 PF14851.6 PVD29922.1 - 0.07 12.8 0.3 0.076 12.7 0.3 1.1 1 0 0 1 1 1 0 FAM176 family zf-3CxxC PF13695.6 PVD29923.1 - 5.7e-09 36.4 6.4 9.8e-09 35.6 6.4 1.4 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 PVD29923.1 - 0.0005 20.7 13.5 0.0018 19.0 13.5 2.0 1 1 0 1 1 1 1 Zinc-binding domain FYVE_2 PF02318.16 PVD29923.1 - 0.022 15.0 5.5 0.042 14.1 5.5 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger DUF35_N PF12172.8 PVD29923.1 - 0.58 10.1 0.0 0.58 10.1 0.0 3.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-3CxxC_2 PF17180.4 PVD29925.1 - 5.7e-13 49.4 5.3 5.7e-13 49.4 5.3 2.8 1 1 2 3 3 3 1 Zinc-binding domain zf-3CxxC PF13695.6 PVD29925.1 - 3.5e-10 40.2 5.6 3.5e-10 40.2 5.6 2.3 2 1 0 2 2 2 1 Zinc-binding domain RNA_pol_Rpc4 PF05132.14 PVD29925.1 - 0.13 12.7 4.9 0.17 12.3 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 KIAA1328 PF15369.6 PVD29925.1 - 0.21 11.4 10.9 1 9.1 10.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 Sec62 PF03839.16 PVD29925.1 - 0.29 10.6 6.0 0.36 10.3 6.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 PVD29925.1 - 0.57 8.9 6.0 0.55 9.0 6.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 PVD29925.1 - 1 8.5 3.1 0.96 8.6 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 PVD29925.1 - 1.1 7.5 9.1 1.3 7.3 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TMPIT PF07851.13 PVD29925.1 - 2.5 7.2 4.8 3.3 6.9 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Suv3_N PF18114.1 PVD29926.1 - 4.8e-45 152.5 0.1 1.2e-44 151.2 0.1 1.7 1 0 0 1 1 1 1 Suv3 helical N-terminal domain SUV3_C PF12513.8 PVD29926.1 - 2.5e-16 59.3 0.0 6.4e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 PVD29926.1 - 9.9e-16 57.3 1.0 2e-15 56.3 1.0 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 PVD29926.1 - 6.4e-12 45.8 0.0 3.8e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ALMS_motif PF15309.6 PVD29927.1 - 2.1e-29 102.7 17.5 2.1e-29 102.7 17.5 6.1 5 2 0 5 5 5 1 ALMS motif PRIMA1 PF16101.5 PVD29927.1 - 0.77 9.8 4.9 2.7 8.1 4.9 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mtc PF03820.17 PVD29928.1 - 2.4e-126 421.0 1.1 3e-126 420.7 1.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Fringe PF02434.16 PVD29929.1 - 3.7e-14 52.8 1.1 2.4e-13 50.1 1.1 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD29929.1 - 3.4e-07 30.3 0.1 0.00052 19.9 0.2 2.3 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 PVD29930.1 - 7.2e-09 35.4 0.2 1e-08 34.9 0.2 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD29930.1 - 3.6e-05 23.7 0.1 7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Galactosyltransferase TPD52 PF04201.15 PVD29931.1 - 2.3 7.8 7.2 0.3 10.7 0.4 2.6 2 0 0 2 2 2 0 Tumour protein D52 family EF-hand_1 PF00036.32 PVD29932.1 - 8.7e-21 71.9 6.5 3.9e-07 29.1 0.4 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PVD29932.1 - 3e-19 69.3 4.2 8.4e-16 58.2 1.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD29932.1 - 4.3e-17 60.5 4.8 9.4e-08 31.4 0.2 3.2 2 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PVD29932.1 - 6.6e-15 53.8 6.0 3.7e-06 26.2 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PVD29932.1 - 4.5e-14 52.0 4.3 1.1e-06 28.4 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD29932.1 - 2.8e-07 30.8 1.9 3.5e-06 27.3 0.3 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD29932.1 - 5e-06 26.4 2.3 0.01 15.7 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PVD29932.1 - 0.00022 21.0 2.7 0.00063 19.5 0.3 2.3 2 1 0 2 2 2 1 EF hand PMBR PF09373.10 PVD29932.1 - 0.001 19.1 0.0 0.66 10.2 0.0 3.1 3 0 0 3 3 3 1 Pseudomurein-binding repeat TerB PF05099.13 PVD29932.1 - 0.0028 17.6 0.3 0.027 14.4 0.0 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_9 PF14658.6 PVD29932.1 - 0.017 15.5 0.2 0.049 14.0 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain DUF5580 PF17743.1 PVD29932.1 - 0.039 12.5 0.0 0.039 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) CagS PF16707.5 PVD29932.1 - 0.039 14.0 0.1 0.058 13.4 0.1 1.4 1 1 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori EF-hand_11 PF08976.11 PVD29932.1 - 0.061 14.2 0.1 0.096 13.6 0.1 1.4 1 1 1 2 2 2 0 EF-hand domain Hpt PF01627.23 PVD29932.1 - 0.11 12.7 0.2 0.4 11.0 0.1 1.7 2 0 0 2 2 2 0 Hpt domain PRESAN PF09687.10 PVD29932.1 - 0.16 12.5 2.6 0.32 11.5 0.2 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal UPF0154 PF03672.13 PVD29932.1 - 0.17 11.9 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) HLH PF00010.26 PVD29933.1 - 2.1e-17 62.8 3.1 3.2e-17 62.2 3.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 PVD29933.1 - 3.8e-13 50.7 1.1 8e-13 49.7 0.8 1.7 1 1 1 2 2 2 1 Neuronal helix-loop-helix transcription factor Ank_2 PF12796.7 PVD29934.1 - 2.1e-08 34.6 0.0 7.4e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29934.1 - 0.00012 22.6 0.0 0.83 10.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD29934.1 - 0.0045 17.4 0.0 3.2 8.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PVD29934.1 - 0.035 14.7 0.0 44 5.1 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 PVD29934.1 - 0.047 14.0 0.0 0.42 11.0 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeats (many copies) RPEL PF02755.15 PVD29934.1 - 0.2 11.4 1.2 13 5.7 0.6 2.4 2 0 0 2 2 2 0 RPEL repeat BBIP10 PF14777.6 PVD29935.1 - 5.3e-30 102.8 8.0 6.1e-30 102.6 8.0 1.0 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 PhzC-PhzF PF02567.16 PVD29936.1 - 5.6e-33 114.6 0.0 3.7e-18 66.0 0.0 2.8 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein Sigma70_r3 PF04539.16 PVD29936.1 - 0.13 12.3 0.1 0.69 10.1 0.1 1.9 1 1 1 2 2 2 0 Sigma-70 region 3 zf-C4 PF00105.18 PVD29937.1 - 6.3e-20 71.4 10.6 1.7e-19 70.1 10.6 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29937.1 - 0.00027 20.6 0.9 0.0012 18.5 0.9 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cytochrome_C7 PF14522.6 PVD29937.1 - 0.15 12.1 1.4 0.36 10.9 1.4 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-RRPl_C4 PF17026.5 PVD29937.1 - 9.8 6.3 9.3 0.88 9.7 3.5 2.3 3 1 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type SNRNP27 PF08648.12 PVD29938.1 - 2.1e-28 98.2 3.5 2.7e-28 97.8 3.5 1.2 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RVT_1 PF00078.27 PVD29939.1 - 2e-30 105.9 0.0 3.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 PVD29939.1 - 2.6e-16 59.2 0.3 1.1e-15 57.2 0.4 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNRNP27 PF08648.12 PVD29939.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 2.2 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins RRM_7 PF16367.5 PVD29939.1 - 0.012 15.7 0.1 0.059 13.5 0.1 2.3 1 1 0 1 1 1 0 RNA recognition motif Dimer_Tnp_hAT PF05699.14 PVD29940.1 - 0.024 14.4 0.1 1.2 9.0 0.1 2.5 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region Dynein_C PF18199.1 PVD29941.1 - 1.4e-10 40.9 0.0 1.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 PVD29942.1 - 5.2e-75 253.0 4.0 5.2e-75 253.0 4.0 4.7 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PVD29942.1 - 4.7e-61 206.6 0.1 2.8e-30 105.4 0.0 4.5 3 1 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 PVD29942.1 - 3.2e-39 134.8 2.7 7.2e-39 133.7 0.0 3.1 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 PVD29942.1 - 2e-31 108.9 0.0 9.8e-23 80.6 0.0 3.6 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_C PF18199.1 PVD29942.1 - 1.8e-26 93.1 0.2 6.4e-26 91.3 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD29942.1 - 3.8e-25 88.3 0.5 1.9e-13 50.1 0.0 4.8 4 1 0 4 4 4 3 ATP-binding dynein motor region MT PF12777.7 PVD29942.1 - 3.5e-23 82.2 2.5 6.5e-21 74.7 0.1 2.4 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD29942.1 - 2.6e-16 59.8 0.0 2.6e-14 53.3 0.0 3.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD29942.1 - 4.8e-14 52.6 1.1 3.9e-13 49.6 0.1 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD29942.1 - 3.6e-13 49.7 0.0 0.0012 18.9 0.0 4.1 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD29942.1 - 2.9e-10 40.8 0.0 0.14 12.5 0.0 4.8 3 0 0 3 3 3 3 AAA ATPase domain AAA PF00004.29 PVD29942.1 - 4.8e-09 36.7 0.0 0.0096 16.3 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD29942.1 - 2.1e-08 34.5 0.0 0.32 11.3 0.0 4.4 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 PVD29942.1 - 5e-08 33.6 0.0 0.16 12.5 0.0 4.6 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 PVD29942.1 - 1.3e-06 28.9 0.1 0.18 12.3 0.0 4.5 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 PVD29942.1 - 1.8e-06 28.3 0.0 1 9.7 0.0 4.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 PVD29942.1 - 4.2e-06 27.0 0.1 0.35 11.0 0.0 3.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 PVD29942.1 - 1e-05 25.5 0.0 0.13 12.1 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 PVD29942.1 - 1.8e-05 24.5 0.0 0.67 9.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_lid_11 PF18198.1 PVD29942.1 - 3.5e-05 23.7 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain TsaE PF02367.17 PVD29942.1 - 4.6e-05 23.4 0.0 4.6 7.3 0.1 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_1 PF17857.1 PVD29942.1 - 5.9e-05 23.2 0.1 0.043 14.0 0.0 3.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_28 PF13521.6 PVD29942.1 - 8e-05 22.9 0.0 2.3 8.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 PVD29942.1 - 9.6e-05 22.7 0.0 2.4 8.6 0.0 4.2 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 PVD29942.1 - 0.00016 21.2 0.3 2.1 7.7 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PVD29942.1 - 0.00026 20.6 0.4 0.036 13.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 PVD29942.1 - 0.0011 18.9 0.1 5.3 6.9 0.0 4.0 3 0 0 3 3 3 0 NACHT domain Rad17 PF03215.15 PVD29942.1 - 0.0018 18.2 0.7 1.2 9.0 0.2 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 PVD29942.1 - 0.017 15.2 0.0 1.3 9.1 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 PVD29942.1 - 0.022 14.5 1.7 16 5.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 PVD29942.1 - 0.023 14.6 0.6 27 4.6 0.0 4.0 3 0 0 3 3 3 0 NTPase cobW PF02492.19 PVD29942.1 - 0.033 13.8 0.4 7.8 6.0 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 PVD29942.1 - 0.037 13.8 0.2 8.7 6.1 0.1 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 PVD29942.1 - 0.074 12.7 0.2 9.8 5.7 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 PVD29942.1 - 0.074 12.8 0.0 15 5.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Roc PF08477.13 PVD29942.1 - 0.11 12.7 0.2 70 3.7 0.0 3.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF3287 PF11690.8 PVD29942.1 - 0.12 12.1 2.5 0.32 10.7 1.1 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3287) PhoH PF02562.16 PVD29942.1 - 0.14 11.6 0.0 24 4.3 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Ank_2 PF12796.7 PVD29943.1 - 3e-23 82.2 9.9 0.00012 22.6 0.0 6.1 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29943.1 - 1.8e-20 73.0 6.1 0.00026 21.5 0.0 7.9 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29943.1 - 4.1e-15 55.7 3.7 0.041 14.2 0.0 7.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Dpy-30 PF05186.13 PVD29943.1 - 2.8e-12 46.1 0.1 6.7e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif Ank_3 PF13606.6 PVD29943.1 - 1.8e-09 37.0 9.1 4.2 8.3 0.1 9.5 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 PVD29943.1 - 9e-09 35.4 5.0 0.21 12.1 0.0 7.2 7 1 0 7 7 7 3 Ankyrin repeat Macro PF01661.21 PVD29944.1 - 1.4e-06 28.3 0.0 8.3e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Macro domain AA_kinase PF00696.28 PVD29945.1 - 1.9e-38 132.4 0.6 3.7e-38 131.5 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.22 PVD29945.1 - 1.1e-13 50.6 0.3 2.6e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Corona_S2 PF01601.16 PVD29945.1 - 0.057 11.9 1.1 0.092 11.2 1.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3088 PF11287.8 PVD29945.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) ACT_6 PF13740.6 PVD29945.1 - 0.1 12.6 0.2 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 ACT domain LETM1 PF07766.13 PVD29946.1 - 5.8e-103 343.9 7.2 5.8e-103 343.9 7.2 3.4 4 1 1 5 5 5 1 LETM1-like protein EF-hand_1 PF00036.32 PVD29946.1 - 0.02 14.4 1.8 0.46 10.2 0.8 3.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 PVD29946.1 - 0.024 14.6 0.2 1.2 9.3 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain EZH2_N PF18601.1 PVD29946.1 - 2 8.8 5.4 1.9 8.9 0.0 3.5 3 0 0 3 3 3 0 EZH2 N-terminal domain Rhomboid PF01694.22 PVD29947.1 - 1.1e-19 70.9 3.4 1.8e-19 70.3 3.4 1.3 1 0 0 1 1 1 1 Rhomboid family DUF89 PF01937.19 PVD29947.1 - 0.0019 17.2 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF89 TMPIT PF07851.13 PVD29947.1 - 4.6 6.4 7.1 0.16 11.2 0.5 1.8 2 0 0 2 2 2 0 TMPIT-like protein RNase_P_p30 PF01876.16 PVD29948.1 - 1.6e-57 194.5 0.4 2e-57 194.1 0.4 1.1 1 0 0 1 1 1 1 RNase P subunit p30 WD40 PF00400.32 PVD29949.1 - 1.1e-31 108.4 13.7 5e-07 30.3 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 PVD29949.1 - 8.2e-25 86.4 1.6 1.6e-24 85.5 1.6 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 PVD29949.1 - 7.9e-10 38.9 2.5 0.047 14.0 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 PVD29949.1 - 2.9e-09 36.7 0.2 7.5e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD29949.1 - 2e-07 30.7 0.0 5.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 PVD29949.1 - 2.6e-06 26.4 6.7 0.057 12.1 0.1 4.1 2 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 PVD29949.1 - 4.2e-05 23.0 0.5 0.0036 16.7 0.4 2.5 1 1 1 2 2 2 1 WD40-like domain F-box_5 PF18511.1 PVD29949.1 - 0.011 15.3 0.3 0.039 13.5 0.3 2.0 1 1 0 1 1 1 0 F-box eIF2A PF08662.11 PVD29949.1 - 0.049 13.5 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 PVD29949.1 - 0.064 12.0 1.8 4.5 5.9 0.1 3.5 1 1 2 3 3 3 0 Nup133 N terminal like DUF5046 PF16465.5 PVD29949.1 - 0.093 12.2 0.0 12 5.2 0.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) RNase_HII PF01351.18 PVD29950.1 - 9.9e-55 185.5 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII CBF PF03914.17 PVD29951.1 - 9.9e-28 97.3 1.8 3.8e-27 95.4 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 PVD29951.1 - 9e-20 70.9 0.1 9e-20 70.9 0.1 2.7 2 1 0 2 2 2 1 Nucleolar complex-associated protein XRN_N PF03159.18 PVD29951.1 - 0.014 14.8 0.8 0.032 13.6 0.8 1.6 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus CHD5 PF04420.14 PVD29951.1 - 0.92 9.4 8.9 0.99 9.3 7.2 1.9 2 1 0 2 2 2 0 CHD5-like protein DSBA PF01323.20 PVD29952.1 - 0.24 11.2 7.3 0.15 11.8 4.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain FMN_bind_2 PF04299.12 PVD29954.1 - 0.0014 18.4 0.2 0.0046 16.7 0.2 1.9 1 0 0 1 1 1 1 Putative FMN-binding domain CC190 PF15768.5 PVD29954.1 - 0.66 10.0 3.1 1.1 9.2 3.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Macoilin PF09726.9 PVD29954.1 - 2.3 6.7 4.7 3.1 6.2 4.7 1.1 1 0 0 1 1 1 0 Macoilin family PACT_coil_coil PF10495.9 PVD29955.1 - 4.6e-23 81.6 0.3 4.6e-23 81.6 0.3 9.2 6 0 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ATG16 PF08614.11 PVD29955.1 - 0.0011 19.3 13.9 0.0011 19.3 13.9 28.7 12 9 12 26 26 26 2 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 PVD29955.1 - 0.0076 16.3 0.4 0.0076 16.3 0.4 14.6 15 0 0 15 15 15 2 Protein of unknown function (DUF1192) NPH-II PF12011.8 PVD29955.1 - 0.066 13.1 0.1 0.43 10.4 0.1 2.5 1 0 0 1 1 1 0 RNA helicase NPH-II Filament PF00038.21 PVD29956.1 - 0.00049 19.8 118.0 0.0083 15.7 34.4 7.1 2 1 2 5 5 5 4 Intermediate filament protein DUF2853 PF11015.8 PVD29957.1 - 0.11 13.1 3.0 0.13 12.9 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2853) DUF2461 PF09365.10 PVD29957.1 - 0.29 11.1 8.6 0.16 11.9 0.5 2.9 3 1 0 3 3 3 0 Conserved hypothetical protein (DUF2461) DUF4407 PF14362.6 PVD29957.1 - 1.1 8.5 38.9 0.31 10.4 8.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3864 PF12980.7 PVD29957.1 - 4.3 7.7 6.2 11 6.4 0.1 3.6 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3864) Lipase_2 PF01674.18 PVD29957.1 - 4.5 6.7 6.1 5.2 6.5 0.7 2.2 2 0 0 2 2 2 0 Lipase (class 2) DUF123 PF01986.16 PVD29957.1 - 9.8 6.8 13.3 1.2 9.7 2.1 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF123 Fez1 PF06818.15 PVD29958.1 - 0.0014 19.1 93.9 0.052 14.0 19.5 6.5 1 1 5 6 6 6 4 Fez1 Filament PF00038.21 PVD29958.1 - 0.0051 16.4 34.4 0.0051 16.4 34.4 6.3 1 1 2 5 5 5 1 Intermediate filament protein TMF_DNA_bd PF12329.8 PVD29958.1 - 0.0054 16.7 5.9 0.0054 16.7 5.9 11.8 5 3 7 12 12 12 3 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 PVD29958.1 - 0.01 15.9 12.4 0.01 15.9 12.4 9.4 5 2 4 9 9 9 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 PVD29958.1 - 0.014 15.6 13.2 0.014 15.6 13.2 7.4 1 1 3 6 6 6 0 Autophagy protein 16 (ATG16) SL4P PF17618.2 PVD29958.1 - 1 9.5 5.8 9.2 6.4 0.3 3.9 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein PDEase_I PF00233.19 PVD29959.1 - 1.1e-81 274.1 0.8 2.7e-81 272.8 0.8 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PVD29959.1 - 1.5e-34 119.5 0.0 2.7e-17 63.6 0.0 3.3 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PVD29959.1 - 2.2e-12 47.4 0.0 3.4e-07 30.6 0.0 2.9 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 PVD29959.1 - 1e-07 32.4 0.0 0.48 10.8 0.1 4.3 3 1 0 3 3 3 3 GAF domain DUF484 PF04340.12 PVD29959.1 - 0.05 13.3 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 zf-C4 PF00105.18 PVD29961.1 - 1.5e-19 70.2 17.1 4e-19 68.8 17.1 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD29961.1 - 4.2e-07 29.8 0.1 1.3e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor YhfH PF14149.6 PVD29961.1 - 0.022 14.7 2.1 1.1 9.3 0.1 2.9 2 0 0 2 2 2 0 YhfH-like protein zf-RRPl_C4 PF17026.5 PVD29961.1 - 0.041 14.0 10.2 0.074 13.2 10.2 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C4 PF00105.18 PVD29962.1 - 4e-21 75.2 15.5 1.2e-20 73.8 15.5 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Prok-RING_1 PF14446.6 PVD29962.1 - 0.009 15.9 5.9 0.009 15.9 5.9 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RRPl_C4 PF17026.5 PVD29962.1 - 0.1 12.7 12.6 0.066 13.3 9.9 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Hormone_2 PF00123.20 PVD29962.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Peptide hormone Ank_3 PF13606.6 PVD29963.1 - 6.4e-13 47.6 0.5 0.00059 20.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 PVD29963.1 - 7.1e-13 48.4 0.3 6.3e-06 26.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 PVD29963.1 - 2.4e-12 47.3 0.0 6.2e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD29963.1 - 1.4e-10 41.4 0.3 9.6e-05 22.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD29963.1 - 1.3e-09 38.1 0.0 0.0021 18.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TPPK_C PF12555.8 PVD29965.1 - 0.36 10.9 1.5 0.88 9.7 1.5 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal RasGEF PF00617.19 PVD29967.1 - 3.5e-22 79.5 0.0 7.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain FERM_M PF00373.18 PVD29967.1 - 2e-12 47.6 0.5 6.9e-12 45.8 0.5 1.9 1 1 0 1 1 1 1 FERM central domain DUF349 PF03993.12 PVD29967.1 - 0.3 11.4 2.2 0.76 10.1 2.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF3915 PF13054.6 PVD29969.1 - 0.048 13.7 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PI-PLC-X PF00388.19 PVD29971.1 - 9.2e-63 210.2 0.0 1.9e-62 209.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 PVD29971.1 - 1.5e-07 31.7 0.0 4.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 PVD29971.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.5 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family MRI PF15325.6 PVD29971.1 - 1.8 9.7 5.8 7.1 7.8 1.9 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection PI-PLC-Y PF00387.19 PVD29972.1 - 1.5e-29 102.7 0.2 3.4e-29 101.5 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.23 PVD29972.1 - 3.1e-28 98.3 0.0 6.1e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.30 PVD29972.1 - 3.5e-08 33.7 0.1 1.3e-07 31.8 0.1 2.0 1 0 0 1 1 1 1 C2 domain TUG-UBL1 PF11470.8 PVD29972.1 - 0.036 14.3 0.0 9 6.6 0.0 2.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain PI3K_rbd PF00794.18 PVD29972.1 - 0.053 13.7 0.0 4.1 7.6 0.0 3.0 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain Ephrin_rec_like PF07699.13 PVD29973.1 - 7.3e-37 124.9 174.0 2.4e-06 27.2 3.8 15.1 1 1 17 18 18 18 16 Putative ephrin-receptor like NCD3G PF07562.14 PVD29973.1 - 7.1 6.7 142.0 0.66 10.0 6.5 12.9 5 2 10 15 15 15 0 Nine Cysteines Domain of family 3 GPCR Mut7-C PF01927.16 PVD29975.1 - 0.016 15.3 0.3 0.022 14.8 0.3 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain COS PF18568.1 PVD29975.1 - 0.21 11.6 0.2 0.66 10.0 0.1 1.8 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain 7tm_1 PF00001.21 PVD29976.1 - 1.1e-49 169.2 16.1 1.6e-49 168.7 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29976.1 - 3.3e-08 33.2 15.1 4.7e-08 32.7 15.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cir_N PF10197.9 PVD29979.1 - 2.3e-15 56.5 3.6 2.3e-15 56.5 3.6 3.0 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 PVD29979.1 - 0.0017 18.2 0.2 0.0045 16.8 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Pentapeptide_4 PF13599.6 PVD29980.1 - 0.0036 17.4 30.2 23 5.2 0.1 8.5 4 2 3 7 7 7 6 Pentapeptide repeats (9 copies) Carb_anhydrase PF00194.21 PVD29982.1 - 6.4e-82 274.9 0.0 7.2e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD29983.1 - 4.3e-85 285.3 0.0 5.1e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Xan_ur_permease PF00860.20 PVD29984.1 - 1.7e-89 300.2 24.8 2.2e-89 299.9 24.8 1.1 1 0 0 1 1 1 1 Permease family Colicin_D PF11429.8 PVD29984.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Colicin D Mab-21 PF03281.14 PVD29985.1 - 9.4e-44 149.9 5.2 9.3e-27 94.1 0.0 2.8 3 0 0 3 3 3 2 Mab-21 protein Focal_AT PF03623.13 PVD29985.1 - 0.052 13.5 1.4 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region Complex1_LYR PF05347.15 PVD29985.1 - 0.14 12.3 0.1 31 4.7 0.0 2.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) D123 PF07065.14 PVD29986.1 - 3.3e-22 79.0 0.3 8.2e-22 77.7 0.3 1.6 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 PVD29986.1 - 0.0005 19.9 0.1 0.0019 18.1 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 PVD29986.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DUF745 PF05335.13 PVD29986.1 - 0.2 11.4 0.2 0.34 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NARG2_C PF10505.9 PVD29987.1 - 1.8e-35 122.4 0.0 5e-35 120.9 0.0 1.7 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus 7tm_1 PF00001.21 PVD29988.1 - 1.3e-70 237.8 14.9 1.6e-70 237.5 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD29988.1 - 1.3e-08 34.6 16.3 2e-08 34.0 16.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD29988.1 - 9.6e-06 25.4 16.7 9.6e-06 25.4 16.7 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2970 PF11174.8 PVD29988.1 - 0.033 14.0 3.3 0.18 11.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) MgtE PF01769.16 PVD29988.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.5 2 1 0 2 2 2 0 Divalent cation transporter Secretin_N_2 PF07655.13 PVD29989.1 - 0.23 12.0 14.9 0.45 11.1 14.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Kelch_1 PF01344.25 PVD29990.1 - 8.3e-44 146.9 1.5 1.8e-12 46.6 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PVD29990.1 - 8.8e-37 124.2 5.0 1.6e-11 44.1 0.0 5.3 2 2 3 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PVD29990.1 - 1.2e-25 89.2 2.1 1.4e-05 25.2 0.0 5.4 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD29990.1 - 4.2e-23 80.4 2.1 5.8e-08 32.4 0.0 5.3 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 PVD29990.1 - 7.6e-22 77.1 0.5 2.3e-07 30.7 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD29990.1 - 1.3e-18 66.5 0.1 8.9e-05 22.4 0.0 4.4 4 0 0 4 4 4 3 Kelch motif SNAPc_SNAP43 PF09808.9 PVD29991.1 - 3e-55 187.1 0.8 3e-55 187.1 0.8 2.2 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF1741 PF08427.10 PVD29992.1 - 3e-81 272.5 5.4 3.9e-81 272.1 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Occludin_ELL PF07303.13 PVD29992.1 - 0.17 12.6 0.6 1.4 9.7 0.0 2.7 3 0 0 3 3 3 0 Occludin homology domain Sel1 PF08238.12 PVD29993.1 - 1.3e-07 32.0 7.2 0.0062 17.2 0.3 3.5 3 1 0 3 3 3 2 Sel1 repeat RabGAP-TBC PF00566.18 PVD29994.1 - 8.2e-49 166.2 0.0 8.2e-49 166.2 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TF_Zn_Ribbon PF08271.12 PVD29995.1 - 3.2e-07 29.8 13.0 0.00047 19.6 3.5 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding TFIIB PF00382.19 PVD29995.1 - 0.0002 21.4 0.1 0.79 9.8 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Lar_restr_allev PF14354.6 PVD29995.1 - 0.00044 20.6 3.4 0.39 11.1 0.3 2.5 2 0 0 2 2 2 2 Restriction alleviation protein Lar DZR PF12773.7 PVD29995.1 - 0.0079 16.2 3.7 0.48 10.5 0.2 2.7 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 PVD29995.1 - 0.032 13.7 5.0 11 5.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain TackOD1 PF18551.1 PVD29995.1 - 0.1 12.2 2.5 8.6 6.0 0.3 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DUF2318 PF10080.9 PVD29995.1 - 0.27 11.4 2.6 1.2 9.2 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DnaJ_CXXCXGXG PF00684.19 PVD29995.1 - 2.1 8.8 5.8 2.1 8.8 0.7 2.6 2 0 0 2 2 2 0 DnaJ central domain GATA PF00320.27 PVD29995.1 - 2.8 7.6 6.1 3.6 7.3 0.7 2.8 3 0 0 3 3 3 0 GATA zinc finger zf-ISL3 PF14690.6 PVD29995.1 - 2.9 8.6 6.5 43 4.9 0.3 3.6 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Nudix_N_2 PF14803.6 PVD29995.1 - 3.2 7.8 7.6 1.1 9.2 0.3 2.9 2 2 0 2 2 2 0 Nudix N-terminal UPF0547 PF10571.9 PVD29995.1 - 3.9 7.6 9.9 59 3.9 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 PVD29995.1 - 5.9 7.1 9.9 20 5.4 0.1 4.0 3 1 2 5 5 5 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 PVD29995.1 - 8.2 6.5 7.4 18 5.4 0.6 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PKcGMP_CC PF16808.5 PVD29997.1 - 0.032 14.1 0.3 0.032 14.1 0.3 8.9 9 0 0 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase baeRF_family2 PF18844.1 PVD29997.1 - 0.48 10.5 0.0 0.48 10.5 0.0 3.6 5 0 0 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 2 TUDOR PF00567.24 PVD29998.1 - 4.6e-90 297.9 0.1 2.1e-25 89.1 0.0 4.6 4 0 0 4 4 4 4 Tudor domain RRM_1 PF00076.22 PVD29998.1 - 6.6e-11 41.9 0.0 2.2e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.18 PVD29998.1 - 2.9e-07 30.5 19.8 7.1e-07 29.2 19.8 1.8 1 0 0 1 1 1 1 MYND finger Agenet PF05641.12 PVD29998.1 - 4.1e-06 27.2 0.0 8.5 6.9 0.0 4.7 4 0 0 4 4 4 2 Agenet domain SMN PF06003.12 PVD29998.1 - 7.8e-06 25.3 5.5 0.037 13.3 0.0 4.7 6 0 0 6 6 6 3 Survival motor neuron protein (SMN) RRM_5 PF13893.6 PVD29998.1 - 0.0011 18.6 0.0 0.0043 16.6 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HIT PF04438.16 PVD29998.1 - 0.0034 17.2 15.5 0.0088 15.9 15.5 1.7 1 0 0 1 1 1 1 HIT zinc finger Tudor_4 PF18358.1 PVD29998.1 - 0.023 14.3 1.3 4 7.1 0.1 3.4 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain DBD_Tnp_Hermes PF10683.9 PVD29998.1 - 0.073 12.8 0.1 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain RRM_7 PF16367.5 PVD29998.1 - 0.088 12.9 1.1 0.31 11.2 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif MDMPI_C PF07398.11 PVD29998.1 - 0.21 12.5 0.1 0.7 10.8 0.1 1.9 1 0 0 1 1 1 0 MDMPI C-terminal domain DUF3652 PF12372.8 PVD29999.1 - 1.7e-15 56.6 5.7 2.3e-15 56.2 1.0 2.8 2 0 0 2 2 2 1 Huntingtin protein region NAD_binding_9 PF13454.6 PVD29999.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HEAT PF02985.22 PVD29999.1 - 0.086 13.1 0.0 0.82 10.1 0.0 2.8 1 0 0 1 1 1 0 HEAT repeat HEAT_EZ PF13513.6 PVD29999.1 - 0.13 12.8 0.2 3.4 8.3 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 PVD30000.1 - 7.4e-06 25.8 0.8 0.14 12.5 0.1 3.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 PVD30000.1 - 0.033 14.6 0.3 1.4 9.3 0.1 2.7 3 0 0 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 PVD30000.1 - 0.055 14.1 0.1 1.5 9.4 0.0 2.4 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PVD30000.1 - 0.12 10.9 0.7 0.39 9.2 0.8 1.6 1 1 1 2 2 2 0 Adaptin N terminal region PTP_N PF12453.8 PVD30000.1 - 0.15 11.8 0.3 0.35 10.6 0.3 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Peptidase_M19 PF01244.21 PVD30001.1 - 3.7e-106 354.9 0.0 2.4e-105 352.2 0.0 2.4 3 0 0 3 3 3 1 Membrane dipeptidase (Peptidase family M19) LSDAT_euk PF18139.1 PVD30001.1 - 8.4e-73 245.0 0.0 1.3e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 PVD30001.1 - 8.3e-22 77.4 0.0 2.7e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 PVD30001.1 - 9.2e-08 31.6 22.7 2e-07 30.5 22.7 1.5 1 0 0 1 1 1 1 Ion transport protein 7tm_1 PF00001.21 PVD30003.1 - 0.00052 19.4 0.1 0.00077 18.9 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Myosin_head PF00063.21 PVD30004.1 - 1.4e-204 681.2 10.2 2.6e-105 353.1 0.2 3.1 1 1 2 3 3 3 3 Myosin head (motor domain) Myosin_TH1 PF06017.13 PVD30004.1 - 2.1e-39 135.1 0.1 3.9e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_16 PF13191.6 PVD30004.1 - 0.032 14.6 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 PVD30004.1 - 0.034 13.4 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 PVD30004.1 - 0.081 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain fn3 PF00041.21 PVD30005.1 - 3.5e-11 43.3 1.6 2.1e-05 24.8 0.1 3.6 3 1 0 3 3 3 3 Fibronectin type III domain Pkinase_Tyr PF07714.17 PVD30006.1 - 4.9e-95 317.7 0.0 6.3e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD30006.1 - 3.9e-42 144.4 0.0 4.2e-28 98.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 PVD30006.1 - 0.088 11.6 0.2 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 PVD30006.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Packaging_FI PF14000.6 PVD30006.1 - 0.85 10.1 3.4 0.3 11.5 0.2 1.9 2 0 0 2 2 2 0 DNA packaging protein FI 7tm_2 PF00002.24 PVD30007.1 - 2.7e-15 56.3 4.9 3.9e-15 55.8 4.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HMG_box PF00505.19 PVD30008.1 - 3.4e-13 49.8 6.9 8.8e-13 48.5 6.9 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD30008.1 - 5.7e-09 36.5 5.3 5.7e-09 36.5 5.3 1.9 2 0 0 2 2 2 1 HMG-box domain DivIC PF04977.15 PVD30008.1 - 0.0053 16.5 1.4 0.0053 16.5 1.4 3.0 3 1 0 4 4 4 1 Septum formation initiator ZapB PF06005.12 PVD30008.1 - 0.042 14.3 1.0 0.042 14.3 1.0 2.6 3 0 0 3 3 3 0 Cell division protein ZapB CENP-H PF05837.12 PVD30008.1 - 0.085 13.3 5.6 3.2 8.2 2.0 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HMG_box_5 PF14887.6 PVD30008.1 - 0.085 12.8 0.3 0.085 12.8 0.3 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 UPF0449 PF15136.6 PVD30008.1 - 0.55 10.7 5.9 1.2 9.6 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Methyltransf_25 PF13649.6 PVD30009.1 - 1.1e-07 32.4 0.0 1.9e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD30009.1 - 1.4e-07 32.1 0.0 2.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD30009.1 - 2.8e-06 26.9 0.0 5.9e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PVD30009.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD30009.1 - 0.0024 18.6 0.0 0.0038 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PVD30009.1 - 0.0073 16.2 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 PVD30009.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain 7tm_2 PF00002.24 PVD30010.1 - 2.9e-31 108.6 6.4 3.9e-31 108.2 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30011.1 - 3.3e-09 36.9 1.3 4.8e-09 36.4 0.2 1.9 2 0 0 2 2 2 1 Hormone receptor domain Neuralized PF07177.12 PVD30016.1 - 8.8e-94 311.4 0.0 3.6e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 PVD30016.1 - 5.4e-13 48.6 13.3 9.5e-13 47.8 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD30016.1 - 0.00018 21.3 12.9 0.00034 20.4 12.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD30016.1 - 0.36 10.7 12.1 0.72 9.7 12.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 PVD30017.1 - 4.5e-36 124.2 0.0 2.7e-35 121.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30017.1 - 7.5e-25 87.8 0.0 4.6e-24 85.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30017.1 - 9.2e-07 28.9 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD30017.1 - 5.6e-06 26.0 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ArgJ PF01960.18 PVD30017.1 - 0.013 14.2 0.1 0.025 13.3 0.0 1.3 1 1 0 1 1 1 0 ArgJ family Sacchrp_dh_NADP PF03435.18 PVD30017.1 - 0.021 15.1 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Acyltransferase PF01553.21 PVD30017.1 - 0.079 12.6 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Acyltransferase THF_DHG_CYH_C PF02882.19 PVD30017.1 - 0.12 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EGF_CA PF07645.15 PVD30019.1 - 6e-09 36.0 9.8 6e-09 36.0 9.8 2.5 3 0 0 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.7 PVD30019.1 - 0.00041 20.2 6.7 0.0097 15.8 0.6 3.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD30019.1 - 0.0011 19.1 13.6 0.0013 18.8 7.9 2.9 2 0 0 2 2 2 1 EGF domain FXa_inhibition PF14670.6 PVD30019.1 - 0.0066 16.7 5.1 0.0066 16.7 5.1 3.3 3 2 1 4 4 4 1 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 PVD30019.1 - 0.0081 16.4 6.7 0.032 14.5 6.7 2.1 1 1 0 1 1 1 1 Pvs28 EGF domain hEGF PF12661.7 PVD30019.1 - 0.012 16.2 1.0 0.012 16.2 1.0 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 PVD30019.1 - 0.026 14.8 5.0 0.026 14.8 5.0 3.1 2 0 0 2 2 2 0 EGF-like domain Kinesin PF00225.23 PVD30020.1 - 5.2e-114 380.6 0.0 5.2e-114 380.6 0.0 3.4 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD30020.1 - 7.6e-24 84.4 0.0 7.6e-24 84.4 0.0 2.9 3 1 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 PVD30020.1 - 5.5e-11 43.0 1.4 5.5e-11 43.0 1.4 5.9 2 2 2 5 5 5 1 Kinesin-associated microtubule-binding BTAD PF03704.17 PVD30020.1 - 0.0057 17.1 10.4 0.0094 16.4 1.5 3.1 2 0 0 2 2 2 1 Bacterial transcriptional activator domain zf-C3HC4_3 PF13920.6 PVD30021.1 - 1.2e-09 37.9 6.4 2.9e-09 36.6 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30021.1 - 0.0012 18.8 9.2 0.002 18.0 8.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Peptidase_U49 PF10463.9 PVD30021.1 - 0.017 14.9 0.9 0.023 14.4 0.9 1.3 1 0 0 1 1 1 0 Peptidase U49 zf-RING_2 PF13639.6 PVD30021.1 - 0.07 13.5 12.2 0.093 13.1 10.5 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 PVD30021.1 - 1.3 8.9 8.8 3.6 7.5 8.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.17 PVD30021.1 - 4.1 7.4 10.2 30 4.6 0.3 3.5 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_3 PF13920.6 PVD30022.1 - 1.3e-09 37.7 7.3 2.1e-09 37.1 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD30022.1 - 0.00055 19.8 7.0 0.00088 19.1 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD30022.1 - 0.0088 16.0 10.9 0.018 15.0 10.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD30022.1 - 0.025 14.9 9.3 0.045 14.1 9.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PVD30022.1 - 4 7.4 10.4 8.9 6.2 10.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C4 PF00105.18 PVD30023.1 - 1.2e-21 76.9 15.9 3e-21 75.7 15.9 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD30023.1 - 6.7e-13 48.7 4.1 1.4e-12 47.6 4.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor APO_RNA-bind PF05634.11 PVD30023.1 - 0.014 14.8 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 APO RNA-binding Ank_2 PF12796.7 PVD30029.1 - 5.6e-10 39.7 4.4 3.2e-05 24.4 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD30029.1 - 1.8e-06 28.4 0.1 0.00032 21.2 0.0 2.6 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD30029.1 - 5.4e-05 23.4 0.7 0.00098 19.5 0.3 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 PVD30029.1 - 0.00018 21.7 0.2 0.3 11.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PVD30029.1 - 0.027 14.8 0.6 2.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Amidinotransf PF02274.17 PVD30030.1 - 1.6e-13 50.5 0.0 3.2e-11 42.9 0.0 2.6 1 1 0 1 1 1 1 Amidinotransferase HEAT_2 PF13646.6 PVD30031.1 - 1.2e-22 80.0 0.6 1.2e-08 35.2 0.4 5.4 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 PVD30031.1 - 3.1e-11 42.5 6.1 1.4 9.4 0.1 7.4 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.6 PVD30031.1 - 5.5e-06 26.8 0.6 0.12 13.0 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat RICTOR_V PF14668.6 PVD30031.1 - 0.1 12.8 0.1 0.4 10.9 0.1 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 CTP_transf_like PF01467.26 PVD30033.1 - 3e-09 37.2 0.0 3.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Nop14 PF04147.12 PVD30034.1 - 1e-195 652.6 43.7 1.4e-124 417.3 6.8 2.5 1 1 1 2 2 2 2 Nop14-like family Noc2 PF03715.13 PVD30034.1 - 0.0051 16.1 1.1 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Noc2p family AIF-MLS PF14962.6 PVD30034.1 - 0.56 10.2 6.4 1.9 8.5 6.4 1.7 1 1 0 1 1 1 0 Mitochondria Localisation Sequence Tmpp129 PF10272.9 PVD30035.1 - 7.5e-94 314.9 1.3 8.9e-94 314.7 1.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor DUF3577 PF12101.8 PVD30035.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3577) HVSL PF09749.9 PVD30035.1 - 0.014 14.8 0.3 0.023 14.1 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein SET PF00856.28 PVD30036.1 - 4.9e-14 53.1 0.0 9.8e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PVD30036.1 - 1.7e-05 24.8 8.2 1.7e-05 24.8 8.2 2.4 3 0 0 3 3 3 1 MYND finger zf_C2H2_10 PF18414.1 PVD30036.1 - 0.028 14.0 0.9 0.028 14.0 0.9 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF2256 PF10013.9 PVD30036.1 - 0.88 9.7 5.8 3.9 7.7 3.1 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Cu-oxidase_2 PF07731.14 PVD30037.1 - 3.1e-46 156.5 39.0 1.1e-12 47.9 1.1 12.8 11 2 0 11 11 11 10 Multicopper oxidase Cu-oxidase_3 PF07732.15 PVD30037.1 - 9.1e-37 125.7 18.3 3.2e-09 36.8 0.0 8.5 9 0 0 9 9 9 5 Multicopper oxidase Cupredoxin_1 PF13473.6 PVD30037.1 - 0.037 14.1 0.0 36 4.5 0.0 3.6 3 0 0 3 3 3 0 Cupredoxin-like domain Hydrolase_like PF13242.6 PVD30038.1 - 3.1e-22 78.4 0.0 7.4e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 PVD30038.1 - 2.1e-17 63.1 0.0 3.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD30038.1 - 1.4e-12 48.4 0.3 3e-09 37.5 0.2 3.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PVD30038.1 - 1.3e-07 31.9 0.0 1.5e-05 25.1 0.0 2.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 PVD30038.1 - 0.0039 16.8 0.0 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Nuf2 PF03800.14 PVD30038.1 - 0.13 12.3 0.0 3.7 7.7 0.0 2.3 1 1 0 1 1 1 0 Nuf2 family 7tm_1 PF00001.21 PVD30039.1 - 3.4e-73 246.2 0.5 4.6e-73 245.8 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30039.1 - 1.2e-08 34.6 11.9 1.8e-07 30.8 11.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD30039.1 - 1.9e-07 31.0 8.9 3.8e-07 30.0 8.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD30039.1 - 2e-05 24.5 6.4 2e-05 24.5 6.4 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 PVD30039.1 - 4.8 6.5 12.6 0.2 11.0 6.2 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 PVD30040.1 - 2e-06 27.3 0.9 3.1e-06 26.7 0.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rogdi_lz PF10259.9 PVD30041.1 - 0.043 13.3 2.6 0.071 12.6 0.7 2.0 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein EAP30 PF04157.16 PVD30041.1 - 0.061 12.6 1.2 0.093 12.0 1.2 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family YlqD PF11068.8 PVD30041.1 - 0.072 13.5 1.0 0.13 12.6 1.0 1.4 1 0 0 1 1 1 0 YlqD protein TMF_TATA_bd PF12325.8 PVD30041.1 - 0.2 11.9 3.2 0.37 11.0 3.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-Di19 PF05605.12 PVD30042.1 - 2.6e-19 69.2 5.3 2.6e-19 69.2 5.3 2.1 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 PVD30042.1 - 3.5e-11 42.7 6.2 3.5e-11 42.7 6.2 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C6H2 PF15801.5 PVD30042.1 - 0.39 11.1 0.3 0.39 11.1 0.3 4.0 3 1 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding adh_short PF00106.25 PVD30043.1 - 1.8e-07 30.9 0.2 3.9e-07 29.7 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30043.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PVD30043.1 - 0.00093 18.7 0.0 0.0033 16.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4523 PF15023.6 PVD30044.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) KdgT PF03812.13 PVD30045.1 - 0.018 14.4 0.0 1.1 8.6 0.0 2.3 3 0 0 3 3 3 0 2-keto-3-deoxygluconate permease Ribosomal_L7Ae PF01248.26 PVD30045.1 - 0.16 11.7 0.0 4.1 7.2 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Gal-3-0_sulfotr PF06990.11 PVD30047.1 - 3e-12 46.1 0.2 3.6e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 PVD30048.1 - 1.2e-18 67.2 0.1 1.5e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD30048.1 - 7.4e-05 22.8 0.1 0.00011 22.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family OppC_N PF12911.7 PVD30048.1 - 0.056 13.4 0.7 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Gal-3-0_sulfotr PF06990.11 PVD30049.1 - 4.6e-42 144.3 0.4 6.1e-42 143.9 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD30049.1 - 2.6e-05 24.3 0.0 4.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 PVD30050.1 - 3.1e-49 168.0 6.4 3.9e-49 167.6 6.4 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD30050.1 - 3.9e-07 30.2 0.5 8.6e-07 29.1 0.5 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 PVD30050.1 - 0.0013 19.1 0.7 0.0028 18.1 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase family Lectin_C PF00059.21 PVD30051.1 - 3.9e-09 37.2 3.1 3.9e-09 37.2 3.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 PVD30051.1 - 0.015 15.2 4.6 0.015 15.2 4.6 1.9 1 1 1 2 2 2 0 PAN domain PAN_4 PF14295.6 PVD30051.1 - 0.13 12.2 0.4 0.13 12.2 0.4 3.0 3 0 0 3 3 3 0 PAN domain RRM_1 PF00076.22 PVD30052.1 - 0.00056 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C69 PF03577.15 PVD30053.1 - 3.1e-08 33.0 0.0 7e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 PVD30053.1 - 0.017 14.8 0.0 0.089 12.5 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Patatin PF01734.22 PVD30055.1 - 5.4e-28 98.6 0.0 9.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase BTB_2 PF02214.22 PVD30055.1 - 0.038 14.3 0.4 1.7 9.1 0.1 2.5 2 0 0 2 2 2 0 BTB/POZ domain Patatin PF01734.22 PVD30056.1 - 5.9e-27 95.2 0.0 9.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_1 PF00036.32 PVD30056.1 - 1.4e-05 24.3 0.1 4.1e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PVD30056.1 - 2e-05 24.1 0.5 6.9e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PVD30056.1 - 0.0002 21.7 0.1 0.00069 20.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair RuvA_C PF07499.13 PVD30056.1 - 0.0013 19.1 0.0 0.018 15.5 0.1 2.3 2 0 0 2 2 2 1 RuvA, C-terminal domain EF-hand_8 PF13833.6 PVD30056.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DivIVA PF05103.13 PVD30056.1 - 0.13 12.3 1.9 35 4.5 0.0 3.2 3 0 0 3 3 3 0 DivIVA protein EF-hand_5 PF13202.6 PVD30056.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.7 1 0 0 1 1 1 0 EF hand YL1 PF05764.13 PVD30059.1 - 0.31 11.1 16.4 0.31 11.1 16.4 1.0 1 0 0 1 1 1 0 YL1 nuclear protein YqfQ PF14181.6 PVD30059.1 - 5.4 7.2 7.7 6.3 7.0 7.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein Ribosomal_L28e PF01778.17 PVD30060.1 - 2.2e-34 118.6 1.0 2.2e-34 118.6 1.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 PVD30060.1 - 6.9e-21 74.7 0.8 6.9e-21 74.7 0.8 1.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region NRDE-2 PF08424.10 PVD30060.1 - 0.069 12.3 1.7 0.084 12.0 1.7 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference zf-CCHC_5 PF14787.6 PVD30061.1 - 0.0096 15.6 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger An_peroxidase PF03098.15 PVD30062.1 - 2.6e-167 557.6 0.0 4.2e-167 556.9 0.0 1.3 1 1 0 1 1 1 1 Animal haem peroxidase TSP_1 PF00090.19 PVD30062.1 - 3.6e-14 52.7 42.5 1.3e-05 25.3 9.2 3.6 3 0 0 3 3 3 3 Thrombospondin type 1 domain MFS_1 PF07690.16 PVD30063.1 - 0.022 13.7 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 PVD30064.1 - 3.5e-13 49.2 25.1 3e-09 36.3 10.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF805 PF05656.14 PVD30064.1 - 5 7.6 6.1 6.1 7.3 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Mlh1_C PF16413.5 PVD30065.1 - 6e-96 321.0 0.0 9.3e-96 320.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 PVD30065.1 - 5.1e-32 110.0 1.0 1.2e-31 108.8 0.5 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PVD30065.1 - 4.1e-14 52.6 0.0 1e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PVD30065.1 - 2.9e-07 31.0 0.1 2.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 PVD30065.1 - 0.046 13.5 0.4 6 6.6 0.1 2.7 3 0 0 3 3 3 0 MutL C terminal dimerisation domain WD40 PF00400.32 PVD30066.1 - 1.5e-13 51.0 1.5 0.026 15.4 0.0 5.9 4 0 0 4 4 4 3 WD domain, G-beta repeat NACHT PF05729.12 PVD30066.1 - 4.6e-13 49.4 0.2 1.5e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 PVD30066.1 - 2e-06 28.3 0.0 7.6e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF4062 PF13271.6 PVD30066.1 - 3.5e-06 27.3 0.0 2.1e-05 24.8 0.0 2.4 2 0 0 2 2 1 1 Domain of unknown function (DUF4062) ATPase_2 PF01637.18 PVD30066.1 - 1.7e-05 24.9 0.0 0.00016 21.7 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ANAPC4_WD40 PF12894.7 PVD30066.1 - 0.00053 20.2 0.4 18 5.7 0.0 5.1 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 PVD30066.1 - 0.00098 19.4 0.0 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD30066.1 - 0.0053 16.3 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 PVD30066.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD30066.1 - 0.11 13.1 0.0 0.54 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 PVD30066.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TRC8_N PF13705.6 PVD30067.1 - 6.7e-126 421.1 47.2 7.8e-126 420.9 47.2 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-C3HC4_2 PF13923.6 PVD30067.1 - 5e-11 42.3 4.9 1.1e-10 41.2 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD30067.1 - 2.4e-10 40.6 6.3 5.6e-10 39.4 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD30067.1 - 1.7e-08 34.2 5.5 3.4e-08 33.2 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD30067.1 - 2.1e-08 33.9 4.2 4.1e-08 33.0 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD30067.1 - 2.5e-07 30.5 5.6 5.7e-07 29.3 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD30067.1 - 5.2e-07 29.8 8.5 4.3e-06 26.9 8.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD30067.1 - 3.2e-06 27.1 2.4 7.6e-06 25.9 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD30067.1 - 6.1e-06 26.1 6.1 1.2e-05 25.1 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PVD30067.1 - 1.8e-05 24.4 3.1 6.1e-05 22.7 3.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PVD30067.1 - 0.00048 20.1 5.6 0.0038 17.2 5.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 PVD30067.1 - 0.0035 16.7 0.7 0.0051 16.2 0.7 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Zn_ribbon_17 PF17120.5 PVD30067.1 - 0.13 11.9 10.8 0.027 14.1 6.6 2.1 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 PVD30067.1 - 0.35 11.0 3.2 0.92 9.7 3.2 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 PVD30067.1 - 0.87 9.8 6.5 11 6.3 6.5 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 PVD30067.1 - 0.95 9.6 5.9 2.6 8.3 5.9 1.8 1 0 0 1 1 1 0 RING-variant domain TRC8_N PF13705.6 PVD30068.1 - 1.1e-131 440.2 37.8 1.3e-131 440.0 37.8 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-C3HC4_2 PF13923.6 PVD30068.1 - 1.8e-09 37.3 7.3 1.8e-09 37.3 7.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD30068.1 - 2.6e-09 37.3 8.4 8.1e-09 35.7 8.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD30068.1 - 2.6e-06 27.6 10.2 1.8e-05 24.9 10.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PVD30068.1 - 5.1e-05 23.1 6.9 5.1e-05 23.1 6.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD30068.1 - 0.00012 21.8 5.6 0.00012 21.8 5.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD30068.1 - 0.00086 19.1 5.9 0.00086 19.1 5.9 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD30068.1 - 0.0013 18.7 2.3 0.0049 16.9 2.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD30068.1 - 0.0017 18.3 8.0 0.0017 18.3 8.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD30068.1 - 0.012 15.7 5.9 0.047 13.7 5.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PVD30068.1 - 0.015 15.0 4.6 0.015 15.0 4.6 2.0 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 PVD30068.1 - 0.11 12.2 8.0 0.34 10.6 8.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PVD30068.1 - 1.4 9.2 6.9 4.6 7.5 6.9 2.0 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PVD30068.1 - 2.4 8.4 8.0 13 6.0 8.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 PVD30068.1 - 5.3 7.3 9.5 0.7 10.1 3.3 2.6 3 0 0 3 3 2 0 zinc RING finger of MSL2 zf-H2C2_2 PF13465.6 PVD30069.1 - 4.4e-36 121.7 61.7 7.3e-08 32.5 1.7 9.1 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 PVD30069.1 - 3.1e-31 106.1 67.2 7.8e-06 26.1 1.0 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD30069.1 - 3.5e-24 83.4 63.8 0.0019 18.9 0.7 8.7 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 PVD30069.1 - 3.1e-13 49.6 50.3 0.011 16.1 0.5 9.3 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD30069.1 - 1.5e-11 44.2 36.2 0.35 11.2 1.3 8.5 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD30069.1 - 0.00013 21.9 55.6 0.026 14.5 3.8 8.6 8 0 0 8 8 8 4 C2H2-type zinc finger GAGA PF09237.11 PVD30069.1 - 0.0063 16.3 4.5 0.0063 16.3 4.5 5.5 3 1 2 6 6 6 1 GAGA factor C1_4 PF07975.12 PVD30069.1 - 0.062 13.5 31.9 2 8.7 3.9 5.9 3 1 3 6 6 6 0 TFIIH C1-like domain BolA PF01722.18 PVD30069.1 - 0.24 11.7 7.3 3.7 7.9 0.2 4.0 2 1 1 4 4 4 0 BolA-like protein zf_UBZ PF18439.1 PVD30069.1 - 2.8 7.6 26.7 0.8 9.3 0.2 6.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Sortilin-Vps10 PF15902.5 PVD30070.1 - 3e-54 184.5 0.0 5.1e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PVD30070.1 - 3.8e-35 121.7 3.4 5.4e-35 121.2 3.4 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 PVD30070.1 - 4.8e-18 64.8 7.9 3e-11 43.0 1.4 2.6 2 0 0 2 2 2 2 PKD domain DUF4448 PF14610.6 PVD30070.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) BNR PF02012.20 PVD30070.1 - 0.92 9.8 12.1 3.6 8.0 0.7 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat Ribosomal_L26 PF16906.5 PVD30071.1 - 8.2e-29 99.9 0.6 1.1e-28 99.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 PVD30071.1 - 2.5e-07 30.4 10.2 6.8e-07 29.0 9.6 2.2 1 1 0 1 1 1 1 KOW motif SspH PF08141.12 PVD30071.1 - 0.0069 16.5 1.5 0.014 15.5 0.4 2.0 1 1 1 2 2 2 1 Small acid-soluble spore protein H family TatD_DNase PF01026.21 PVD30071.1 - 0.096 12.0 0.3 0.15 11.4 0.3 1.4 1 1 0 1 1 1 0 TatD related DNase PIP49_C PF12260.8 PVD30072.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Nucleos_tra2_C PF07662.13 PVD30073.1 - 4.6e-75 252.0 3.7 8.8e-75 251.1 3.7 1.5 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Telomerase_RBD PF12009.8 PVD30073.1 - 1.4e-30 106.1 6.1 1.4e-30 106.1 6.1 2.9 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain Nucleos_tra2_N PF01773.20 PVD30073.1 - 5.8e-24 84.5 0.9 2e-23 82.8 0.9 1.9 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus RVT_1 PF00078.27 PVD30073.1 - 6.1e-07 29.2 0.1 0.00077 19.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Gate PF07670.14 PVD30073.1 - 0.0067 16.7 7.6 0.0067 16.7 7.6 2.3 2 0 0 2 2 2 1 Nucleoside recognition YMF19 PF02326.15 PVD30073.1 - 0.76 10.6 6.3 0.32 11.8 2.0 2.8 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF4205 PF13898.6 PVD30074.1 - 9.1e-121 403.0 0.0 1.4e-120 402.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) FOP_dimer PF09398.10 PVD30074.1 - 0.00032 20.9 0.2 0.00097 19.3 0.2 1.8 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Kelch_4 PF13418.6 PVD30075.1 - 1.4e-28 98.6 3.3 1.7e-08 34.3 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain LCM PF04072.14 PVD30075.1 - 2.7e-28 99.2 0.0 6.6e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 PVD30075.1 - 2.1e-23 81.8 2.6 2.2e-05 24.3 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PVD30075.1 - 1.6e-15 56.7 2.6 0.22 11.8 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PVD30075.1 - 1.3e-10 40.7 3.1 0.011 15.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD30075.1 - 1.4e-08 34.4 6.0 0.074 13.1 0.1 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PVD30075.1 - 4e-07 30.2 0.1 4e-07 30.2 0.1 5.0 7 0 0 7 7 7 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 PVD30075.1 - 0.00086 18.6 0.0 0.012 14.8 0.0 2.6 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus RAG2 PF03089.14 PVD30075.1 - 0.0068 15.4 0.1 0.062 12.3 0.0 2.3 1 1 0 1 1 1 1 Recombination activating protein 2 Polyketide_cyc PF03364.20 PVD30076.1 - 1.2e-24 87.0 0.1 1.3e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PVD30076.1 - 6.4e-05 23.3 0.0 7.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Aa_trans PF01490.18 PVD30077.1 - 1.6e-63 214.8 31.4 2e-63 214.5 31.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PVD30077.1 - 3 6.8 28.5 0.088 11.8 17.1 2.8 1 1 2 3 3 3 0 Tryptophan/tyrosine permease family BCHF PF07284.11 PVD30077.1 - 4.4 7.3 16.5 0.57 10.2 3.6 3.5 2 1 2 4 4 4 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Sterol-sensing PF12349.8 PVD30078.1 - 8.2e-50 168.6 9.5 1.5e-49 167.7 9.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 PVD30078.1 - 3.4e-20 71.8 1.6 5.3e-20 71.1 1.6 1.3 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 PVD30078.1 - 6.5e-19 67.9 6.7 2.5e-06 28.1 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD30078.1 - 5.1e-07 29.9 0.0 0.023 15.0 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD30078.1 - 7.1e-05 21.6 0.0 0.5 9.0 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 PVD30078.1 - 0.06 12.9 0.0 0.44 10.1 0.0 2.2 3 0 0 3 3 3 0 PQQ-like domain GCR1_C PF12550.8 PVD30078.1 - 0.17 12.3 0.1 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Rer1 PF03248.13 PVD30078.1 - 0.31 10.8 6.1 2 8.1 0.3 3.1 3 0 0 3 3 3 0 Rer1 family Baculo_11_kDa PF06143.11 PVD30078.1 - 0.61 9.7 0.0 0.61 9.7 0.0 3.8 5 0 0 5 5 5 0 Baculovirus 11 kDa family WBP-1 PF11669.8 PVD30079.1 - 0.019 15.6 18.9 0.13 12.9 18.9 2.4 1 1 0 1 1 1 0 WW domain-binding protein 1 EF-hand_1 PF00036.32 PVD30080.1 - 5.3e-20 69.4 3.3 1e-06 27.9 0.2 3.1 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 PVD30080.1 - 3e-15 54.9 4.1 6.7e-07 28.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PVD30080.1 - 3.5e-15 56.2 3.6 9.9e-12 45.2 0.8 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD30080.1 - 4.7e-14 51.0 1.3 2.7e-05 23.7 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PVD30080.1 - 6.6e-11 41.9 5.2 8.1e-05 22.4 0.6 2.4 1 1 2 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD30080.1 - 4e-06 27.1 0.8 0.00011 22.5 0.1 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 PVD30080.1 - 9.2e-06 24.5 0.1 1e-05 24.3 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 PVD30080.1 - 5.5e-05 22.9 4.0 0.003 17.4 0.6 2.6 1 1 1 2 2 2 2 EF hand RHH_7 PF16777.5 PVD30080.1 - 0.00051 20.4 0.3 0.00069 19.9 0.3 1.2 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG EF-hand_4 PF12763.7 PVD30080.1 - 0.0018 18.2 0.9 0.0088 16.0 0.4 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Glyco_hydro_46 PF01374.18 PVD30080.1 - 0.05 13.2 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 CCD48 PF15799.5 PVD30080.1 - 0.061 11.6 0.0 0.069 11.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF1456 PF07308.13 PVD30080.1 - 0.11 12.8 1.1 11 6.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) UIM PF02809.20 PVD30081.1 - 0.043 13.8 0.2 0.043 13.8 0.2 2.5 3 0 0 3 3 3 0 Ubiquitin interaction motif EF-hand_7 PF13499.6 PVD30082.1 - 0.042 14.3 0.3 0.3 11.6 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair Sel1 PF08238.12 PVD30082.1 - 0.051 14.3 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Sel1 repeat DUF2244 PF10003.9 PVD30082.1 - 6.2 6.5 5.7 0.69 9.6 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Ribosomal_L7Ae PF01248.26 PVD30083.1 - 2.3e-26 91.4 0.0 3.6e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PVD30083.1 - 0.00019 21.5 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF643 PF04867.12 PVD30083.1 - 0.016 15.8 0.3 0.023 15.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF643) DUF5305 PF17231.2 PVD30083.1 - 0.023 14.1 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RRM_1 PF00076.22 PVD30084.1 - 3.4e-45 151.7 0.6 1e-19 70.1 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD30084.1 - 0.00027 20.7 0.0 0.22 11.4 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 PVD30084.1 - 0.0011 19.0 0.4 1.3 9.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif DUF4878 PF12870.7 PVD30084.1 - 0.22 11.8 9.5 3.8 7.8 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4878) TROVE PF05731.11 PVD30085.1 - 5.2e-102 342.2 1.3 8.2e-102 341.5 1.3 1.2 1 0 0 1 1 1 1 TROVE domain WD40 PF00400.32 PVD30085.1 - 4.3e-64 210.9 72.5 9.9e-07 29.4 0.2 17.8 17 0 0 17 17 17 12 WD domain, G-beta repeat DUF4062 PF13271.6 PVD30085.1 - 9.8e-20 70.7 0.0 1.2e-18 67.2 0.0 2.9 3 0 0 3 3 2 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.7 PVD30085.1 - 2.3e-16 59.9 5.9 0.029 14.7 0.0 9.7 3 1 7 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD30085.1 - 9.6e-11 41.2 6.1 0.076 12.0 0.1 7.5 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein APAF1_C PF17908.1 PVD30085.1 - 1.9e-08 34.4 0.7 6.7e-08 32.6 0.4 2.1 2 0 0 2 2 2 1 APAF-1 helical domain eIF2A PF08662.11 PVD30085.1 - 4.9e-06 26.5 1.5 0.85 9.5 0.0 4.9 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 PVD30085.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 PVD30085.1 - 0.00012 21.5 0.2 0.11 11.8 0.0 3.6 3 0 0 3 3 3 1 WD40-like domain AAA_16 PF13191.6 PVD30085.1 - 0.00013 22.4 0.0 0.00052 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.6 PVD30085.1 - 0.01 15.5 2.3 0.033 13.8 0.1 2.7 2 0 0 2 2 2 0 PQQ-like domain ABC_tran PF00005.27 PVD30085.1 - 0.029 14.9 0.2 0.079 13.5 0.2 1.7 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 PVD30085.1 - 0.04 13.1 0.2 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain PQQ PF01011.21 PVD30085.1 - 0.043 13.8 2.1 3.1 7.9 0.1 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat Ploopntkinase3 PF18751.1 PVD30085.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 PVD30085.1 - 0.06 13.4 0.7 0.19 11.8 0.7 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 PVD30085.1 - 0.081 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C30 PF05409.13 PVD30085.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 AAA_22 PF13401.6 PVD30085.1 - 0.092 13.0 0.1 0.81 10.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain PQQ_3 PF13570.6 PVD30085.1 - 0.1 13.1 8.4 4.7 7.8 0.1 4.8 4 1 1 5 5 5 0 PQQ-like domain Roc PF08477.13 PVD30085.1 - 0.36 11.1 1.6 8.3 6.7 0.1 3.4 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PBP1_TM PF14812.6 PVD30085.1 - 2.3 8.7 6.7 8.2 6.9 6.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Homeodomain PF00046.29 PVD30086.1 - 4.7e-21 74.4 2.0 8.6e-21 73.5 2.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD30086.1 - 0.0093 15.9 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF5546 PF17700.1 PVD30086.1 - 0.016 15.6 4.2 0.034 14.5 4.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5546) RRN3 PF05327.11 PVD30086.1 - 0.079 11.5 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Siah-Interact_N PF09032.11 PVD30086.1 - 0.086 13.2 1.6 0.16 12.3 0.2 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal ANAPC4_WD40 PF12894.7 PVD30087.1 - 0.0021 18.3 0.0 0.026 14.8 0.0 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD30087.1 - 0.0024 18.6 0.9 0.2 12.6 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.8 PVD30087.1 - 0.017 13.8 0.1 0.022 13.4 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 PVD30087.1 - 0.056 12.7 0.0 0.26 10.5 0.0 1.8 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 PVD30087.1 - 0.079 12.5 0.1 0.2 11.2 0.1 1.7 1 1 0 1 1 1 0 PQQ-like domain TPR_2 PF07719.17 PVD30088.1 - 9.4e-26 87.8 25.8 0.00087 19.2 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 PVD30088.1 - 2.2e-24 83.6 24.0 0.00041 20.3 0.0 10.4 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD30088.1 - 1.1e-23 82.0 33.2 2.3e-05 24.0 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 PVD30088.1 - 7.5e-20 69.9 20.1 0.0032 18.1 0.1 9.2 8 1 1 9 9 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 PVD30088.1 - 2.7e-16 59.9 9.1 9.2e-16 58.2 2.4 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_6 PF13174.6 PVD30088.1 - 2.2e-10 40.5 24.1 0.22 12.2 0.3 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD30088.1 - 2.2e-10 41.0 23.6 0.00017 22.2 0.0 8.2 6 3 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD30088.1 - 3.8e-10 40.1 24.5 0.04 14.4 0.1 8.1 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD30088.1 - 2.4e-09 36.7 16.7 3.4e-07 29.8 0.1 6.4 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.6 PVD30088.1 - 6.1e-09 36.0 28.5 0.0035 17.6 0.7 7.0 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 PVD30088.1 - 4.8e-08 32.5 20.8 1.5 9.0 0.2 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD30088.1 - 1e-07 31.8 12.9 0.049 14.0 0.0 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD30088.1 - 4.8e-05 23.5 26.9 1.7 8.9 0.1 6.1 5 2 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PVD30088.1 - 0.019 15.1 12.3 0.033 14.3 0.1 5.1 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD30088.1 - 0.023 14.6 17.2 48 4.0 0.7 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TIR_2 PF13676.6 PVD30089.1 - 0.00036 21.1 0.0 0.001 19.7 0.0 1.8 1 0 0 1 1 1 1 TIR domain Exo_endo_phos PF03372.23 PVD30091.1 - 3.8e-06 26.6 0.0 6.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Homeodomain PF00046.29 PVD30093.1 - 6.6e-22 77.1 1.1 1.6e-21 75.9 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD30093.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PVD30093.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 PVD30093.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PXA PF02194.15 PVD30095.1 - 2.8e-45 154.5 4.8 1.3e-43 149.1 4.7 3.1 2 1 0 2 2 2 1 PXA domain EF-hand_1 PF00036.32 PVD30095.1 - 8.4e-34 112.6 12.8 6.8e-05 22.1 0.0 8.9 5 3 3 8 8 8 8 EF hand Nexin_C PF08628.12 PVD30095.1 - 3.5e-26 92.0 0.0 1.9e-25 89.6 0.0 2.4 2 0 0 2 2 1 1 Sorting nexin C terminal EF-hand_7 PF13499.6 PVD30095.1 - 6.7e-25 87.3 3.0 1.6e-05 25.3 0.0 7.8 4 3 2 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 PVD30095.1 - 8.9e-25 84.5 16.2 0.00089 19.0 0.0 9.2 7 2 2 9 9 9 7 EF-hand domain EF-hand_5 PF13202.6 PVD30095.1 - 1.4e-23 81.2 21.0 0.00047 19.5 0.0 8.5 8 1 1 9 9 9 6 EF hand PX PF00787.24 PVD30095.1 - 1.3e-21 76.7 0.0 4.4e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 PVD30095.1 - 3.6e-18 65.9 0.6 1.1e-17 64.4 0.6 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain EF-hand_8 PF13833.6 PVD30095.1 - 6.5e-18 64.3 14.6 0.0014 18.4 0.2 7.8 6 2 2 8 8 8 6 EF-hand domain pair Dockerin_1 PF00404.18 PVD30095.1 - 1.7e-05 24.9 5.3 13 6.1 0.0 6.4 5 2 1 6 6 6 1 Dockerin type I domain DUF3900 PF13039.6 PVD30095.1 - 0.0082 16.1 0.8 5 7.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3900) DNA_mis_repair PF01119.19 PVD30096.1 - 1.8e-23 82.5 0.0 4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PVD30096.1 - 8.9e-11 41.8 0.2 2.2e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 PVD30096.1 - 1.1e-10 41.7 1.3 1.1e-10 41.7 1.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD30096.1 - 8.1e-07 29.6 2.4 8.1e-07 29.6 2.4 2.3 2 0 0 2 2 2 1 HMG-box domain HATPase_c PF02518.26 PVD30096.1 - 3.3e-06 27.6 0.0 8.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin PF00085.20 PVD30097.1 - 3.4e-92 303.2 2.4 2.3e-31 107.8 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 PVD30097.1 - 5e-26 91.7 8.4 2e-19 70.3 2.2 4.5 3 1 1 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 PVD30097.1 - 3.7e-13 49.5 0.3 6e-05 22.5 0.0 4.2 2 2 2 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PVD30097.1 - 5.5e-12 45.8 1.3 0.17 12.2 0.0 6.8 4 3 2 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.6 PVD30097.1 - 9.5e-12 44.9 0.1 0.016 15.4 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 PVD30097.1 - 1.2e-11 45.0 5.9 0.006 17.0 0.0 5.1 3 2 0 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 PVD30097.1 - 5.6e-10 38.8 2.8 2.6e-05 23.4 0.1 3.4 2 1 1 3 3 3 3 Calsequestrin AhpC-TSA PF00578.21 PVD30097.1 - 2.4e-09 37.1 2.5 0.03 14.2 0.0 5.1 4 1 2 6 6 6 3 AhpC/TSA family TraF PF13728.6 PVD30097.1 - 4.3e-06 26.7 0.0 1.3 8.8 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 PVD30097.1 - 0.00017 21.6 0.0 3.6 7.7 0.0 3.8 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_9 PF14595.6 PVD30097.1 - 0.00019 21.2 0.2 8.1 6.2 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin HyaE PF07449.11 PVD30097.1 - 0.0058 16.6 0.0 4 7.4 0.0 3.0 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF3228 PF11539.8 PVD30097.1 - 0.033 13.7 0.0 27 4.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3228) DSBA PF01323.20 PVD30097.1 - 0.035 13.9 4.6 20 4.9 0.1 4.8 4 2 2 6 6 6 0 DSBA-like thioredoxin domain DUF3000 PF11452.8 PVD30097.1 - 0.05 13.1 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3000) Thioredoxin_4 PF13462.6 PVD30097.1 - 0.59 10.3 2.3 74 3.4 0.1 3.9 3 1 1 4 4 4 0 Thioredoxin CENP-B_dimeris PF09026.10 PVD30097.1 - 7.5 7.0 10.8 18 5.8 10.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PDZ PF00595.24 PVD30098.1 - 1.7e-37 127.6 9.2 5.7e-12 45.8 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 PVD30098.1 - 1.2e-16 60.2 0.3 1.7e-06 27.7 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PVD30098.1 - 9.4e-16 57.9 2.5 1.7e-05 25.1 0.1 3.9 3 0 0 3 3 3 3 PDZ domain Par3_HAL_N_term PF12053.8 PVD30098.1 - 1.6e-13 50.6 0.4 4.3e-13 49.3 0.4 1.7 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Xan_ur_permease PF00860.20 PVD30099.1 - 3.1e-76 256.6 30.7 3.1e-75 253.3 30.7 1.9 1 1 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 PVD30100.1 - 9.5e-74 248.4 31.0 1.4e-72 244.6 31.0 2.0 1 1 0 1 1 1 1 Permease family Noc2 PF03715.13 PVD30100.1 - 0.24 10.6 0.5 0.39 9.9 0.5 1.2 1 0 0 1 1 1 0 Noc2p family HLH PF00010.26 PVD30101.1 - 1.6e-15 56.7 0.8 2.5e-15 56.2 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 PVD30101.1 - 0.0021 18.2 0.2 0.0033 17.5 0.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GDH_N PF12466.8 PVD30101.1 - 0.085 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal DUF1682 PF07946.14 PVD30101.1 - 0.2 10.8 3.2 0.35 10.0 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NOA36 PF06524.12 PVD30101.1 - 1.6 8.0 10.3 2.5 7.3 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein HLH PF00010.26 PVD30102.1 - 4.1e-15 55.5 2.1 6.1e-15 54.9 2.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 PVD30103.1 - 3.8e-10 40.2 10.9 0.00022 22.0 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD30103.1 - 0.00057 20.1 0.0 0.066 13.5 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Hist_deacetyl PF00850.19 PVD30107.1 - 1.2e-81 274.6 0.0 1.2e-81 274.6 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylase domain TFIIA PF03153.13 PVD30107.1 - 0.001 19.1 9.6 0.001 19.1 9.6 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3016 PF11454.8 PVD30107.1 - 5.5 6.7 8.9 0.43 10.3 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) KNOX1 PF03790.13 PVD30108.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 KNOX1 domain adh_short PF00106.25 PVD30110.1 - 8.8e-18 64.5 0.2 2.8e-16 59.6 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30110.1 - 6.4e-08 32.4 0.0 0.009 15.6 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase VBS PF08913.10 PVD30112.1 - 0.099 13.1 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Vinculin Binding Site GST_C_3 PF14497.6 PVD30114.1 - 9.9e-22 77.0 0.0 1.6e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD30114.1 - 5.7e-06 26.5 0.0 9.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD30114.1 - 0.0015 18.6 0.1 0.0037 17.2 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PVD30114.1 - 0.042 14.2 0.1 0.31 11.4 0.0 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF3786 PF12654.7 PVD30114.1 - 0.092 12.3 0.1 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Pribosyltran PF00156.27 PVD30115.1 - 2.6e-25 88.8 0.0 3.3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PVD30115.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Phage_F PF02305.17 PVD30115.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) PRTase_2 PF15609.6 PVD30115.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase VWD PF00094.25 PVD30116.1 - 6.3e-93 309.2 7.6 7.1e-31 107.6 0.0 3.6 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 PVD30116.1 - 7.3e-45 151.3 46.6 4.4e-17 62.3 9.9 9.1 9 0 0 9 9 9 3 C8 domain TIL PF01826.17 PVD30116.1 - 9.7e-25 86.6 94.0 4.5e-12 46.0 20.0 12.3 12 0 0 12 12 12 4 Trypsin Inhibitor like cysteine rich domain Mucin2_WxxW PF13330.6 PVD30116.1 - 6.5e-20 71.7 1.5 6.5e-20 71.7 1.5 5.9 7 2 2 9 9 9 1 Mucin-2 protein WxxW repeating region DUF1521 PF07481.11 PVD30116.1 - 2.3e-05 24.4 0.0 0.0005 20.1 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1521) VWC PF00093.18 PVD30116.1 - 0.00082 19.6 9.3 0.00082 19.6 9.3 12.5 6 4 4 10 10 10 2 von Willebrand factor type C domain Mucin2_WxxW PF13330.6 PVD30117.1 - 6.8e-199 645.4 81.9 2.6e-20 73.0 0.2 14.5 14 0 0 14 14 14 13 Mucin-2 protein WxxW repeating region F5_F8_type_C PF00754.25 PVD30117.1 - 6.2e-160 524.1 17.1 1.5e-26 93.0 0.0 7.8 7 0 0 7 7 7 7 F5/8 type C domain Ldl_recept_a PF00057.18 PVD30117.1 - 4.2e-07 30.1 5.3 4.2e-07 30.1 5.3 5.3 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A VWC PF00093.18 PVD30117.1 - 0.0001 22.5 11.6 0.0001 22.5 11.6 8.7 7 1 0 7 7 7 2 von Willebrand factor type C domain UPA PF17217.3 PVD30117.1 - 0.089 12.7 0.3 13 5.7 0.0 3.8 4 0 0 4 4 4 0 UPA domain 7tm_2 PF00002.24 PVD30118.1 - 2.5e-64 216.9 29.1 3.1e-64 216.6 29.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF5134 PF17197.4 PVD30118.1 - 0.092 12.6 4.4 5.6 6.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) DUF2749 PF10907.8 PVD30118.1 - 0.15 12.2 0.1 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Nucleos_tra2_C PF07662.13 PVD30119.1 - 2.5e-61 207.1 0.3 2.5e-61 207.1 0.3 2.9 2 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30119.1 - 5.1e-22 78.2 1.1 5.1e-22 78.2 1.1 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD30119.1 - 1e-07 32.2 7.8 1e-07 32.2 7.8 2.5 3 0 0 3 3 3 1 Nucleoside recognition Orf78 PF06024.12 PVD30119.1 - 0.014 15.7 4.2 0.56 10.5 0.0 3.4 3 0 0 3 3 3 0 Orf78 (ac78) Nucleos_tra2_C PF07662.13 PVD30120.1 - 2.7e-72 243.0 4.8 2.7e-72 243.0 4.8 2.8 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30120.1 - 5.8e-22 78.1 2.7 5.8e-22 78.1 2.7 3.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD30120.1 - 1.1e-06 28.9 8.1 1.1e-06 28.9 8.1 3.3 4 2 0 4 4 4 1 Nucleoside recognition Vma12 PF11712.8 PVD30120.1 - 0.0081 16.2 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Orf78 PF06024.12 PVD30120.1 - 0.028 14.7 4.0 4.4 7.6 0.0 3.5 3 0 0 3 3 3 0 Orf78 (ac78) HAGH_C PF16123.5 PVD30121.1 - 4.3e-20 72.0 0.1 7.8e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PVD30121.1 - 1.7e-13 51.0 1.3 1.3e-12 48.1 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 PVD30121.1 - 1.5e-05 24.9 0.6 7.3e-05 22.7 0.4 2.2 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PVD30121.1 - 9.5e-05 22.0 0.4 0.0005 19.6 0.3 2.1 1 1 1 2 2 2 1 Beta-lactamase superfamily domain RasGEF PF00617.19 PVD30122.1 - 6.2e-23 81.9 0.1 1.2e-22 81.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PVD30122.1 - 2.7e-10 40.4 0.2 7.2e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF4551 PF15087.6 PVD30122.1 - 6.2 5.5 12.6 1.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) KIND PF16474.5 PVD30124.1 - 6.5e-13 49.0 4.2 7.8e-08 32.4 0.0 3.6 3 1 1 4 4 4 2 Kinase non-catalytic C-lobe domain Pkinase PF00069.25 PVD30124.1 - 0.00084 18.8 0.0 5.9 6.2 0.0 4.1 4 0 0 4 4 4 2 Protein kinase domain Pentapeptide_4 PF13599.6 PVD30125.1 - 9.7e-39 131.4 21.0 4.8e-05 23.4 0.7 8.3 1 1 6 8 8 8 8 Pentapeptide repeats (9 copies) Nucleos_tra2_C PF07662.13 PVD30125.1 - 4.7e-35 121.3 1.0 8.9e-35 120.4 1.0 1.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30125.1 - 2.5e-23 82.5 1.8 2.5e-23 82.5 1.8 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Keratin_B2 PF01500.17 PVD30125.1 - 3.3 7.7 97.4 73 3.3 11.2 8.7 2 2 1 3 3 3 0 Keratin, high sulfur B2 protein DUF1360 PF07098.11 PVD30126.1 - 0.53 10.3 2.6 0.52 10.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Nucleos_tra2_C PF07662.13 PVD30127.1 - 3e-55 187.3 3.5 5.4e-55 186.4 3.5 1.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus DEAD PF00270.29 PVD30127.1 - 1.8e-51 174.4 0.0 4e-51 173.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD30127.1 - 2e-28 99.0 0.0 5e-27 94.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nucleos_tra2_N PF01773.20 PVD30127.1 - 1.9e-23 82.8 2.4 1.9e-23 82.8 2.4 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus ResIII PF04851.15 PVD30127.1 - 0.00019 21.5 0.4 0.00082 19.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit hEGF PF12661.7 PVD30128.1 - 0.0076 16.9 7.2 0.022 15.4 7.2 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 PVD30128.1 - 0.01 16.2 16.0 0.012 16.0 14.7 1.8 2 0 0 2 2 2 0 EGF-like domain DUF4982 PF16355.5 PVD30128.1 - 0.32 11.0 1.2 28 4.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4982) EGF PF00008.27 PVD30128.1 - 4.1 7.8 13.4 1.8 8.9 10.8 1.8 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 PVD30129.1 - 0.0039 17.5 15.1 0.0085 16.4 15.1 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 PVD30129.1 - 0.013 16.1 7.2 0.013 16.1 7.2 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 PVD30129.1 - 1.2 9.5 13.3 0.75 10.2 11.0 1.9 2 0 0 2 2 2 0 EGF-like domain VWD PF00094.25 PVD30130.1 - 9.8e-11 42.2 4.4 9.8e-11 42.2 4.4 2.5 2 0 0 2 2 2 1 von Willebrand factor type D domain Rad33 PF08730.10 PVD30130.1 - 0.14 12.2 0.9 0.39 10.7 0.4 2.1 2 0 0 2 2 2 0 Rad33 hEGF PF12661.7 PVD30130.1 - 0.18 12.5 12.5 0.63 10.8 8.6 4.4 2 0 0 2 2 2 0 Human growth factor-like EGF Polysacc_synt_4 PF04669.13 PVD30131.1 - 3.3e-23 82.2 1.3 8.7e-22 77.6 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis SnoaL PF07366.12 PVD30131.1 - 0.1 12.4 0.1 4.9 7.0 0.0 2.2 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase HMG_box PF00505.19 PVD30132.1 - 1.3e-19 70.4 0.5 3.3e-19 69.0 0.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD30132.1 - 3.8e-15 56.2 0.1 1.1e-14 54.8 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain zf-C2H2_jaz PF12171.8 PVD30132.1 - 0.0088 16.3 2.0 0.024 14.9 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PVD30132.1 - 0.012 16.0 1.0 0.012 16.0 1.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MlaC PF05494.12 PVD30132.1 - 0.042 13.6 0.4 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 MlaC protein zf-C3HC PF07967.13 PVD30132.1 - 0.34 11.0 5.0 0.12 12.4 2.1 1.8 2 0 0 2 2 2 0 C3HC zinc finger-like DASH_Dad2 PF08654.10 PVD30132.1 - 0.55 10.7 6.9 1.2 9.7 0.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad2 zf_C2H2_6 PF18450.1 PVD30132.1 - 1.1 9.1 6.1 0.26 11.0 1.9 2.1 2 0 0 2 2 2 0 Zinc Finger domain zf-met PF12874.7 PVD30132.1 - 1.8 9.0 8.9 0.11 12.9 3.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-NF-X1 PF01422.17 PVD30133.1 - 7.3e-11 41.9 96.0 6.8e-06 26.0 11.2 14.8 16 1 0 16 16 16 7 NF-X1 type zinc finger IL4 PF00727.18 PVD30134.1 - 0.046 14.0 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Interleukin 4 RPE65 PF03055.15 PVD30135.1 - 9e-75 252.6 0.0 1.1e-74 252.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF745 PF05335.13 PVD30136.1 - 0.00015 21.6 1.9 0.00015 21.6 1.9 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF745) Ndufs5 PF10200.9 PVD30136.1 - 0.013 15.7 0.6 0.053 13.8 0.6 2.0 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF948 PF06103.11 PVD30136.1 - 0.013 15.7 1.7 0.62 10.4 0.0 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) GM_CSF PF01109.17 PVD30136.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Hemerythrin PF01814.23 PVD30136.1 - 0.13 12.9 0.1 0.13 12.9 0.1 3.1 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Laminin_II PF06009.12 PVD30136.1 - 0.61 10.1 9.1 6 6.9 1.4 3.3 3 0 0 3 3 3 0 Laminin Domain II MnmE_helical PF12631.7 PVD30136.1 - 0.92 9.6 12.5 5 7.2 12.5 2.2 1 1 0 1 1 1 0 MnmE helical domain Rootletin PF15035.6 PVD30136.1 - 1 9.3 15.0 0.28 11.2 10.2 2.4 2 2 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.12 PVD30136.1 - 3.3 7.7 5.7 10 6.1 0.2 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Xan_ur_permease PF00860.20 PVD30137.1 - 1.4e-71 241.2 26.4 2.3e-71 240.6 26.4 1.2 1 0 0 1 1 1 1 Permease family DUF2206 PF09971.9 PVD30137.1 - 0.79 8.4 6.6 1.4 7.6 6.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Bap31 PF05529.12 PVD30137.1 - 1.2 9.0 3.1 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region OapA_N PF08525.11 PVD30137.1 - 3.6 7.6 6.7 0.56 10.2 0.9 2.9 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Granulin PF00396.18 PVD30140.1 - 6.2e-124 404.1 311.6 1.2e-15 57.6 24.7 15.9 15 3 3 18 18 18 10 Granulin SHS2_FTSA PF02491.20 PVD30140.1 - 0.079 13.4 0.0 32 5.0 0.0 3.9 6 0 0 6 6 6 0 SHS2 domain inserted in FTSA DUF92 PF01940.16 PVD30141.1 - 1.1e-63 214.8 7.7 1.6e-63 214.3 7.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 VWD PF00094.25 PVD30142.1 - 5.9e-29 101.4 23.1 2.4e-11 44.2 0.1 6.2 6 1 0 6 6 6 3 von Willebrand factor type D domain EGF_Tenascin PF18720.1 PVD30142.1 - 8.8e-06 25.7 9.6 8.8e-06 25.7 9.6 7.3 8 0 0 8 8 8 3 Tenascin EGF domain EGF_2 PF07974.13 PVD30142.1 - 0.00091 19.5 37.7 0.0013 19.1 13.9 8.3 8 0 0 8 8 8 4 EGF-like domain EphA2_TM PF14575.6 PVD30142.1 - 0.0093 16.8 0.1 0.024 15.5 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD30142.1 - 0.013 15.4 0.0 0.013 15.4 0.0 3.1 2 1 1 3 3 3 0 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD30142.1 - 0.018 15.8 0.3 0.32 11.8 0.1 3.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CD34_antigen PF06365.12 PVD30142.1 - 0.058 13.0 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 CD34/Podocalyxin family VWD PF00094.25 PVD30143.1 - 5.9e-31 107.9 12.3 1.9e-10 41.2 0.0 5.0 4 0 0 4 4 4 4 von Willebrand factor type D domain EGF_Tenascin PF18720.1 PVD30143.1 - 1.2e-07 31.6 77.3 2e-05 24.5 12.5 7.5 6 0 0 6 6 6 4 Tenascin EGF domain EGF_2 PF07974.13 PVD30143.1 - 0.004 17.5 12.7 0.004 17.5 12.7 8.2 8 0 0 8 8 8 4 EGF-like domain DUF982 PF06169.12 PVD30143.1 - 0.023 14.7 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) PAN_1 PF00024.26 PVD30144.1 - 4.5e-22 77.8 26.3 5.3e-09 35.9 3.6 6.8 6 0 0 6 6 6 3 PAN domain VWD PF00094.25 PVD30144.1 - 6.6e-19 68.7 16.2 6.1e-15 55.8 0.0 4.7 5 0 0 5 5 5 2 von Willebrand factor type D domain EGF_2 PF07974.13 PVD30144.1 - 0.0015 18.8 14.3 0.0015 18.8 14.3 8.5 10 0 0 10 10 10 3 EGF-like domain F5_F8_type_C PF00754.25 PVD30144.1 - 0.0024 18.0 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 F5/8 type C domain FPN1 PF06963.12 PVD30146.1 - 2e-111 372.7 11.8 2.8e-111 372.2 11.8 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Imm58 PF15581.6 PVD30146.1 - 0.017 15.2 0.6 10 6.3 0.1 2.9 2 0 0 2 2 2 0 Immunity protein 58 Phageshock_PspD PF09584.10 PVD30146.1 - 0.064 13.3 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) DUF3951 PF13131.6 PVD30146.1 - 0.071 13.3 0.5 0.42 10.8 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Pox_A14 PF05767.12 PVD30146.1 - 1.7 8.9 6.5 0.19 11.9 0.4 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Gemini_mov PF01708.16 PVD30146.1 - 2.3 8.0 5.4 0.78 9.5 0.2 2.9 3 0 0 3 3 3 0 Geminivirus putative movement protein FPN1 PF06963.12 PVD30147.1 - 2.4e-245 814.0 14.2 9.1e-133 443.0 3.7 3.3 2 2 0 2 2 2 2 Ferroportin1 (FPN1) Trypan_glycop PF00913.19 PVD30147.1 - 0.32 10.2 3.5 10 5.3 0.1 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Phage_holin_4_2 PF04020.13 PVD30147.1 - 0.46 11.2 17.3 0.16 12.7 2.3 3.5 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV EIID-AGA PF03613.14 PVD30147.1 - 1.2 8.3 19.2 1.1 8.4 0.2 4.1 4 0 0 4 4 4 0 PTS system mannose/fructose/sorbose family IID component DUF3185 PF11381.8 PVD30147.1 - 1.5 8.9 6.8 18 5.4 0.2 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF347 PF03988.12 PVD30147.1 - 1.8 8.8 13.6 1 9.6 1.6 4.3 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) TPP_enzyme_N PF02776.18 PVD30148.1 - 2.2e-44 151.1 0.0 3.3e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PVD30148.1 - 2.5e-37 127.7 0.0 1.4e-36 125.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PVD30148.1 - 5e-12 45.9 0.5 2.3e-11 43.7 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NMT1_3 PF16868.5 PVD30148.1 - 0.069 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 NMT1-like family TSP_1 PF00090.19 PVD30149.1 - 2.9e-16 59.4 130.3 4.3e-08 33.3 9.6 9.5 9 1 0 9 9 9 6 Thrombospondin type 1 domain TIL PF01826.17 PVD30149.1 - 1.4e-05 25.2 35.2 0.00044 20.4 7.2 13.3 9 5 5 14 14 14 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 PVD30149.1 - 0.00016 21.9 19.0 0.00016 21.9 19.0 11.7 6 4 2 8 8 8 1 von Willebrand factor type C domain NAD_binding_5 PF07994.12 PVD30164.1 - 0.5 9.7 3.6 11 5.3 0.3 2.1 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase TTC5_OB PF16669.5 PVD30165.1 - 1.2 8.8 5.8 13 5.5 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain DUF1892 PF08987.10 PVD30166.1 - 1.6 9.0 36.6 24 5.2 0.8 6.8 6 0 0 6 6 6 0 Protein of unknown function (DUF1892) Ribosomal_60s PF00428.19 PVD30166.1 - 6.6 7.4 25.3 1.2e+02 3.4 0.2 7.5 6 0 0 6 6 6 0 60s Acidic ribosomal protein VWD PF00094.25 PVD30167.1 - 5.1e-26 91.8 9.4 1.1e-11 45.3 2.3 3.9 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 PVD30167.1 - 1.7e-18 66.8 27.5 7.8e-11 42.2 8.0 5.5 6 1 0 6 6 6 2 C8 domain Ldl_recept_a PF00057.18 PVD30167.1 - 2e-16 59.9 49.8 4.6e-09 36.3 11.4 7.5 6 1 1 7 7 7 3 Low-density lipoprotein receptor domain class A TIL PF01826.17 PVD30167.1 - 4.1e-09 36.6 20.0 4.1e-09 36.6 20.0 10.8 7 3 3 10 10 10 2 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 PVD30167.1 - 0.0034 17.6 13.0 0.0034 17.6 13.0 11.2 5 4 6 11 11 11 1 von Willebrand factor type C domain DUF4968 PF16338.5 PVD30167.1 - 0.079 13.3 0.5 0.58 10.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) EGF_2 PF07974.13 PVD30168.1 - 5.6e-05 23.4 9.5 0.00011 22.5 9.5 1.5 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 PVD30168.1 - 0.0003 21.0 6.1 0.0012 19.1 6.1 2.0 1 1 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 PVD30168.1 - 0.096 12.8 6.1 0.17 12.1 6.1 1.3 1 0 0 1 1 1 0 Laminin EGF domain hEGF PF12661.7 PVD30168.1 - 0.1 13.3 7.1 0.1 13.3 7.1 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF MFS_1 PF07690.16 PVD30169.1 - 2.4e-13 49.8 49.6 1e-06 28.0 24.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily DSPc PF00782.20 PVD30170.1 - 7.7e-41 139.0 0.1 1.2e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 PVD30170.1 - 1.9e-08 34.8 0.0 3.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Y_phosphatase PF00102.27 PVD30170.1 - 0.00024 20.8 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PVD30170.1 - 0.021 15.1 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 PVD30170.1 - 0.061 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Abhydrolase_3 PF07859.13 PVD30171.1 - 1.4e-88 296.2 6.6 2.9e-43 148.2 0.1 4.1 2 2 2 4 4 4 4 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD30171.1 - 1.6e-12 47.4 0.1 0.00048 19.7 0.0 4.2 4 0 0 4 4 4 3 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PVD30171.1 - 1.6e-06 28.9 10.9 0.001 19.7 1.4 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family COesterase PF00135.28 PVD30171.1 - 1.8e-06 27.1 0.9 1.9e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.9 PVD30171.1 - 2.2e-05 24.0 1.3 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase DUF2974 PF11187.8 PVD30171.1 - 0.005 16.4 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) AXE1 PF05448.12 PVD30171.1 - 0.01 14.5 1.3 0.2 10.3 0.0 2.5 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 PVD30171.1 - 0.024 13.5 0.1 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Chlorophyllase enzyme Thioesterase PF00975.20 PVD30171.1 - 0.16 12.1 0.2 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Thioesterase domain Homeodomain PF00046.29 PVD30172.1 - 9.2e-23 79.9 3.8 1.6e-22 79.1 3.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD30172.1 - 0.08 12.9 2.2 0.1 12.5 0.1 2.2 3 0 0 3 3 3 0 Homeobox KN domain HTH_28 PF13518.6 PVD30172.1 - 0.2 11.8 2.7 0.99 9.6 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain EGF_Tenascin PF18720.1 PVD30173.1 - 2.9 8.0 6.1 0.56 10.3 2.0 1.9 2 0 0 2 2 2 0 Tenascin EGF domain Homeodomain PF00046.29 PVD30174.1 - 1.2e-21 76.2 3.4 2.2e-21 75.5 3.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD30174.1 - 0.051 13.5 1.9 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 Homeobox KN domain CDC45 PF02724.14 PVD30174.1 - 0.45 8.7 4.5 0.5 8.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.28 PVD30176.1 - 4.2e-49 168.0 0.1 2.6e-48 165.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DEAD PF00270.29 PVD30177.1 - 5.4e-16 58.9 0.0 6.9e-15 55.2 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.23 PVD30177.1 - 1.8e-14 53.4 0.1 1.5e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 HRDC domain HTH_40 PF14493.6 PVD30177.1 - 2.9e-11 43.7 0.0 1.4e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain RecQ_Zn_bind PF16124.5 PVD30177.1 - 1.8e-09 38.2 1.5 4.8e-09 36.8 1.5 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 PVD30177.1 - 6e-09 36.2 0.0 2.3e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD30177.1 - 6.5e-05 23.0 0.0 0.00062 19.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma70_r4_2 PF08281.12 PVD30177.1 - 9.1e-05 22.1 0.4 0.0009 18.9 0.3 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 RQC PF09382.10 PVD30177.1 - 0.086 12.6 0.0 0.79 9.5 0.0 2.4 1 1 0 1 1 1 0 RQC domain Cut12 PF11500.8 PVD30177.1 - 1.5 8.8 5.7 22 5.0 1.6 2.7 2 0 0 2 2 2 0 Spindle pole body formation-associated protein 7tm_1 PF00001.21 PVD30178.1 - 4e-49 167.3 7.9 6.5e-49 166.6 7.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD30178.1 - 1.5e-07 31.4 8.2 2.1e-06 27.7 7.6 2.6 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD30178.1 - 5.4e-07 29.3 8.8 2.4e-06 27.1 8.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD30178.1 - 0.00065 19.1 13.3 0.077 12.3 7.8 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD30178.1 - 0.0093 15.6 9.6 0.026 14.2 9.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PLAC8 PF04749.17 PVD30178.1 - 0.15 13.1 4.0 0.35 11.9 0.5 3.0 3 0 0 3 3 3 0 PLAC8 family PH PF00169.29 PVD30180.1 - 1.2e-28 99.7 0.2 2.1e-14 53.9 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 PVD30180.1 - 1.8e-12 47.6 1.2 6.5e-08 33.0 0.2 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 PVD30180.1 - 1.7e-09 38.1 0.1 0.0041 17.5 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 PVD30180.1 - 2.4e-08 34.1 6.8 0.00018 21.7 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 PVD30180.1 - 0.00019 21.7 0.0 0.052 13.9 0.0 3.0 2 1 1 3 3 3 1 Plant pleckstrin homology-like region PH_13 PF16652.5 PVD30180.1 - 0.0036 17.1 0.1 2.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain DUF4162 PF13732.6 PVD30180.1 - 0.026 15.2 0.0 1 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) PH_6 PF15406.6 PVD30180.1 - 0.12 12.7 0.0 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Beta-lactamase PF00144.24 PVD30181.1 - 8e-52 176.5 0.1 1.2e-51 175.9 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD30182.1 - 2e-56 191.7 0.4 2.5e-56 191.3 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD30183.1 - 5.7e-51 173.7 0.3 7.6e-51 173.3 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD30184.1 - 2.4e-55 188.1 0.0 3.5e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase CD225 PF04505.12 PVD30185.1 - 0.07 13.3 0.7 0.19 11.9 0.7 1.7 1 0 0 1 1 1 0 Interferon-induced transmembrane protein RRM_1 PF00076.22 PVD30186.1 - 4.3e-08 32.9 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHH_8 PF17723.1 PVD30186.1 - 0.073 13.3 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family AIM5 PF17050.5 PVD30186.1 - 0.26 12.1 1.2 4.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 Dynactin_p62 PF05502.13 PVD30187.1 - 2.2 7.0 13.7 2.8 6.6 13.7 1.1 1 0 0 1 1 1 0 Dynactin p62 family ING PF12998.7 PVD30187.1 - 8.2 7.1 21.1 1.2 9.8 13.4 2.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding EXOSC1 PF10447.9 PVD30188.1 - 5.8e-15 55.9 0.4 1.9e-12 47.7 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 PVD30188.1 - 3.2e-10 39.6 0.2 7.6e-10 38.4 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Fra10Ac1 PF09725.9 PVD30189.1 - 1.5e-55 186.6 4.9 3e-55 185.6 4.9 1.5 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 PriA_CRR PF18319.1 PVD30189.1 - 0.031 14.2 0.9 0.058 13.4 0.9 1.5 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain DUF4718 PF15842.5 PVD30189.1 - 0.22 11.3 6.8 0.019 14.7 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) HLH PF00010.26 PVD30190.1 - 6.7e-20 70.8 0.0 6.7e-20 70.8 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 PVD30190.1 - 0.0055 16.3 0.2 0.0089 15.7 0.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HLH PF00010.26 PVD30191.1 - 8e-19 67.4 1.7 1.1e-18 66.9 1.7 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4205 PF13898.6 PVD30192.1 - 7.1e-58 196.2 0.1 9.3e-54 182.6 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_6 PF13405.6 PVD30192.1 - 0.0077 16.1 0.0 0.06 13.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PVD30192.1 - 0.054 13.3 0.1 1.6 8.6 0.2 2.6 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 PVD30192.1 - 0.17 12.4 0.3 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair BNIP3 PF06553.12 PVD30193.1 - 5e-26 91.6 5.8 2.9e-25 89.1 5.8 1.8 1 1 0 1 1 1 1 BNIP3 Arf PF00025.21 PVD30194.1 - 9.3e-42 142.4 0.0 1.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PVD30194.1 - 2.1e-10 40.4 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD30194.1 - 5.8e-09 36.2 0.0 8.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PVD30194.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PVD30194.1 - 6.6e-05 22.4 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD30194.1 - 0.0051 16.4 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD30194.1 - 0.0097 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase G-alpha PF00503.20 PVD30194.1 - 0.015 14.5 0.0 0.05 12.8 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 PVD30194.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arabinose_Iso_C PF11762.8 PVD30194.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain 7tm_1 PF00001.21 PVD30195.1 - 1e-19 70.9 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30195.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD30195.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.0 1 0 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srw PF10324.9 PVD30195.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD30196.1 - 5.1e-31 108.0 7.9 6.1e-31 107.7 7.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30196.1 - 5.4e-07 29.3 7.0 6.4e-07 29.0 7.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD30196.1 - 9.7e-05 22.2 2.0 0.0001 22.2 2.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD30196.1 - 0.0042 16.7 5.4 0.0052 16.5 5.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRR_9 PF14580.6 PVD30200.1 - 1e-13 51.2 5.8 6.9e-13 48.5 5.7 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 PVD30200.1 - 7.7e-11 42.1 23.5 9.4e-05 22.7 5.5 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD30200.1 - 1.3e-05 24.9 19.8 0.00017 21.2 8.3 3.3 1 1 3 4 4 4 4 Leucine rich repeat V-SNARE PF05008.15 PVD30200.1 - 0.1 13.0 5.6 0.25 11.7 0.1 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus LRR_1 PF00560.33 PVD30200.1 - 8.3 7.4 17.7 17 6.4 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 PVD30201.1 - 8e-32 110.6 0.0 6.5e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30201.1 - 1.1e-17 64.2 0.0 1e-09 38.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase PQQ_2 PF13360.6 PVD30201.1 - 0.00028 20.5 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 PVD30201.1 - 0.0085 16.0 0.0 0.84 9.7 0.0 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat FTA2 PF13095.6 PVD30201.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Synaptonemal_3 PF15191.6 PVD30202.1 - 0.02 14.7 0.4 0.029 14.1 0.4 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 zf-H3C2 PF16721.5 PVD30202.1 - 0.033 14.6 0.2 0.054 13.9 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding LMP PF04778.12 PVD30202.1 - 0.046 13.6 0.6 0.06 13.3 0.6 1.2 1 0 0 1 1 1 0 LMP repeated region NHL PF01436.21 PVD30203.1 - 2.1e-16 59.0 0.6 1.4e-05 24.8 0.0 5.8 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 PVD30203.1 - 0.00024 20.8 0.0 0.014 15.0 0.0 2.9 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PVD30203.1 - 0.00095 18.4 0.0 0.039 13.1 0.0 3.0 3 0 0 3 3 3 1 6-bladed beta-propeller DUF5082 PF16888.5 PVD30203.1 - 0.0069 16.7 5.9 0.018 15.4 3.9 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Apolipoprotein PF01442.18 PVD30203.1 - 0.14 12.0 1.2 0.27 11.1 1.2 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 PVD30203.1 - 0.74 9.3 4.4 0.32 10.5 1.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit ATP-synt_E_2 PF08112.11 PVD30203.1 - 0.84 10.0 3.4 20 5.5 2.9 3.3 3 1 1 4 4 4 0 ATP synthase epsilon subunit Flagellin_C PF00700.21 PVD30203.1 - 9 6.7 6.8 1.6 9.1 1.0 2.6 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Phasin PF05597.11 PVD30203.1 - 9.9 6.2 7.0 0.64 10.0 0.6 2.4 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FANCI_HD2 PF14680.6 PVD30204.1 - 3.6e-78 262.1 6.9 3.6e-78 262.1 6.9 2.4 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S4 PF14678.6 PVD30204.1 - 3.7e-71 239.2 2.8 4.4e-71 238.9 0.4 2.3 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_S2 PF14676.6 PVD30204.1 - 7.6e-51 172.7 0.3 7.6e-51 172.7 0.3 3.8 3 1 1 4 4 4 1 FANCI solenoid 2 FANCI_S3 PF14677.6 PVD30204.1 - 5.2e-39 134.2 0.9 5.2e-39 134.2 0.9 2.8 3 1 1 4 4 4 1 FANCI solenoid 3 FANCI_HD1 PF14679.6 PVD30204.1 - 4.9e-24 84.1 1.3 2.8e-23 81.7 0.2 2.9 2 0 0 2 2 2 1 FANCI helical domain 1 FANCI_S1 PF14675.6 PVD30204.1 - 0.0032 17.1 0.8 0.034 13.7 0.2 2.7 2 0 0 2 2 2 1 FANCI solenoid 1 Gal4_dimer PF03902.13 PVD30204.1 - 0.14 12.4 1.6 1.6 8.9 0.1 3.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain MTBP_N PF14918.6 PVD30204.1 - 0.19 11.1 3.4 0.53 9.7 2.4 2.2 2 0 0 2 2 2 0 MDM2-binding GvpK PF05121.12 PVD30204.1 - 0.95 9.5 6.2 1.8 8.6 1.0 3.1 2 0 0 2 2 2 0 Gas vesicle protein K GEN1_C PF18380.1 PVD30204.1 - 7.2 7.6 10.2 22 6.0 10.2 1.8 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DNA_pol_B_palm PF14792.6 PVD30205.1 - 1.4e-35 121.9 0.0 2.8e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 PVD30205.1 - 4e-21 74.9 0.0 7.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 PVD30205.1 - 2.3e-20 72.2 0.2 6.9e-20 70.6 0.2 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 PVD30205.1 - 2.7e-19 69.3 0.0 7.8e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.26 PVD30205.1 - 2.7e-05 24.4 0.1 8.4e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 PVD30205.1 - 0.00012 22.6 0.0 0.21 12.2 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT_2 PF16589.5 PVD30205.1 - 0.00057 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PVD30205.1 - 0.0045 16.9 0.1 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain NTP_transf_2 PF01909.23 PVD30205.1 - 0.0056 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_3 PF12836.7 PVD30205.1 - 0.064 13.5 0.0 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.8 PVD30205.1 - 0.082 13.2 0.0 11 6.3 0.0 2.6 1 1 0 2 2 2 0 Pathogenicity locus Amino_oxidase PF01593.24 PVD30206.1 - 2.1e-13 50.4 0.0 9.2e-13 48.3 0.0 2.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD30206.1 - 1.4e-05 25.2 0.0 0.00044 20.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD30206.1 - 0.0057 16.3 0.2 0.28 10.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase SR-25 PF10500.9 PVD30207.1 - 0.003 17.2 8.1 0.003 17.2 8.1 9.6 6 3 1 8 8 8 1 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 PVD30208.1 - 6.7e-158 513.7 50.6 1.3e-17 64.1 1.4 14.9 1 1 12 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD30208.1 - 7.7e-143 463.2 56.8 6.2e-14 52.2 0.4 20.6 10 5 9 21 21 21 21 Ankyrin repeats (many copies) Ank PF00023.30 PVD30208.1 - 2.3e-124 400.9 84.7 4e-08 33.4 0.4 28.0 27 1 1 28 28 28 25 Ankyrin repeat Ank_5 PF13857.6 PVD30208.1 - 1.3e-115 375.9 71.2 2.4e-11 43.6 0.4 22.2 8 6 15 23 23 23 22 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD30208.1 - 2.2e-115 362.4 57.5 2.6e-05 24.2 0.0 28.3 28 0 0 28 28 28 24 Ankyrin repeat GATase_7 PF13537.6 PVD30208.1 - 0.055 13.4 0.0 20 5.1 0.0 4.8 4 1 1 5 5 5 0 Glutamine amidotransferase domain UDPG_MGDP_dh_C PF03720.15 PVD30208.1 - 0.17 12.4 0.1 54 4.3 0.0 4.7 4 1 1 5 5 5 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF1604 PF07713.13 PVD30208.1 - 0.35 10.7 1.0 40 4.1 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1604) Prok-RING_1 PF14446.6 PVD30208.1 - 1.3 9.0 6.7 19 5.3 0.1 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Vinculin PF01044.19 PVD30209.1 - 7.7e-62 209.8 27.1 6.5e-27 94.2 4.3 4.4 3 2 0 4 4 4 4 Vinculin family Serendipity_A PF05482.12 PVD30209.1 - 1e-05 24.4 1.4 1e-05 24.4 1.4 2.1 2 0 0 2 2 2 1 Serendipity locus alpha protein (SRY-A) SUFU_C PF12470.8 PVD30210.1 - 4.9e-74 248.8 0.1 6.4e-74 248.4 0.1 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 PVD30210.1 - 4.1e-46 157.1 0.0 6.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Presenilin PF01080.17 PVD30210.1 - 4.7 5.9 5.5 7.1 5.3 5.5 1.2 1 0 0 1 1 1 0 Presenilin Actin PF00022.19 PVD30211.1 - 5.3e-99 331.6 0.0 4.8e-98 328.4 0.0 1.9 1 1 0 1 1 1 1 Actin DUF4188 PF13826.6 PVD30211.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) Glyco_hydro_63 PF03200.16 PVD30212.1 - 1.9e-208 693.2 1.5 2.3e-208 692.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 PVD30212.1 - 4e-18 66.3 0.0 1.2e-17 64.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 PVD30212.1 - 0.00048 19.2 0.0 0.00088 18.3 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 PVD30212.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Trehalase RVT_1 PF00078.27 PVD30212.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.28 PVD30213.1 - 5.3e-62 209.8 1.4 1.8e-57 194.8 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD30213.1 - 9.3e-11 42.6 0.1 4.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD30214.1 - 1.1e-46 159.4 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD30214.1 - 1e-18 68.0 0.0 2.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD30215.1 - 4.6e-39 134.2 0.0 5.8e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1294 PF06961.13 PVD30216.1 - 0.2 11.9 1.2 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) 7tm_1 PF00001.21 PVD30216.1 - 1.8 7.8 15.6 9.1 5.5 15.6 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1658 PF07871.11 PVD30217.1 - 0.27 11.2 1.8 0.53 10.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) RRM_1 PF00076.22 PVD30219.1 - 1.3e-43 146.7 0.1 2.4e-13 49.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD30219.1 - 2.2e-07 30.9 0.0 0.11 12.6 0.0 4.0 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 PVD30219.1 - 0.00031 20.3 0.0 0.36 10.4 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD30219.1 - 0.0025 17.9 0.1 10 6.3 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD30219.1 - 0.0032 17.4 0.3 0.59 10.2 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 PVD30219.1 - 0.018 15.0 0.0 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 RL domain RRM_occluded PF16842.5 PVD30219.1 - 0.094 12.6 0.0 0.87 9.5 0.0 2.5 4 0 0 4 4 4 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PVD30219.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 EAF PF09816.9 PVD30220.1 - 4.8e-16 59.0 0.1 1.1e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ion_trans PF00520.31 PVD30221.1 - 5.8e-36 124.0 6.8 8e-36 123.5 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 PVD30221.1 - 3.1e-18 66.0 0.0 6.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 PVD30221.1 - 3.7e-12 46.1 0.0 7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD30221.1 - 2.8e-11 43.2 0.7 2.8e-11 43.2 0.7 2.1 2 0 0 2 2 2 1 Ion channel PAS PF00989.25 PVD30221.1 - 3.2e-10 40.0 0.0 8.4e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 PVD30221.1 - 2.2e-05 24.7 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 PVD30221.1 - 0.00085 19.6 0.0 0.0096 16.2 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 PVD30221.1 - 0.018 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS domain IRK PF01007.20 PVD30221.1 - 0.037 13.8 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF2281 PF10047.9 PVD30222.1 - 0.03 15.0 0.0 0.057 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) DUF4010 PF13194.6 PVD30222.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) SUIM_assoc PF16619.5 PVD30222.1 - 0.081 13.0 10.2 0.27 11.3 5.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_7 PF13499.6 PVD30224.1 - 1.6e-09 38.1 0.4 0.00026 21.4 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD30224.1 - 1.2e-08 33.9 0.3 2e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD30224.1 - 8.2e-08 31.6 0.1 4.4e-06 26.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PVD30224.1 - 5.1e-07 28.9 0.0 1.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 PVD30224.1 - 0.0012 18.6 0.5 2.3 8.1 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair Ferritin PF00210.24 PVD30225.1 - 1.4e-12 47.7 0.2 1.9e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain S1 PF00575.23 PVD30226.1 - 1.1e-40 137.8 30.8 9.1e-09 35.5 0.4 12.1 12 2 0 12 12 11 8 S1 RNA binding domain TPR_19 PF14559.6 PVD30226.1 - 5.2e-11 42.9 0.0 0.0017 18.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD30226.1 - 1.7e-10 41.4 0.0 0.0034 18.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD30226.1 - 2e-08 34.4 3.6 1.4 10.0 0.0 6.1 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD30226.1 - 0.0019 18.1 1.0 20 5.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD30226.1 - 0.005 17.1 1.2 1.9 8.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat S1_2 PF13509.6 PVD30226.1 - 0.0078 16.2 0.9 22 5.2 0.0 4.9 4 1 0 4 4 4 0 S1 domain Coatomer_E PF04733.14 PVD30226.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_6 PF13174.6 PVD30226.1 - 0.038 14.6 4.6 91 4.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 PVD30226.1 - 0.19 10.9 6.3 1.7 7.8 3.7 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TRAM PF01938.20 PVD30226.1 - 0.3 11.1 8.6 2.6 8.1 0.1 5.9 7 1 1 8 8 8 0 TRAM domain Mad3_BUB1_I PF08311.12 PVD30226.1 - 0.38 10.8 1.4 0.95 9.5 0.3 2.3 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TACC_C PF05010.14 PVD30227.1 - 4.7e-39 134.3 34.0 1.2e-38 133.0 34.0 1.7 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal WD40_alt PF14077.6 PVD30227.1 - 0.36 10.7 4.4 0.31 10.9 0.7 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif Svs_4_5_6 PF17381.2 PVD30227.1 - 0.48 11.4 4.8 3.9e+02 2.1 0.0 6.7 6 1 0 6 6 6 0 Seminal vesicle secretory proteins 4/5/6 DUF1515 PF07439.11 PVD30227.1 - 2 8.5 10.1 0.076 13.0 1.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) MFS_1 PF07690.16 PVD30228.1 - 1.7e-20 73.2 26.8 1.7e-20 73.2 26.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 PVD30230.1 - 0.0034 16.7 0.1 0.0039 16.4 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) bZIP_1 PF00170.21 PVD30231.1 - 0.0019 18.3 0.4 0.0061 16.6 0.4 1.9 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 PVD30231.1 - 0.0026 18.0 1.9 0.0026 18.0 1.9 2.4 2 1 1 3 3 2 1 TSC-22/dip/bun family DivIC PF04977.15 PVD30231.1 - 0.0038 17.0 2.1 0.0038 17.0 2.1 2.8 2 1 1 3 3 3 1 Septum formation initiator DUF5320 PF17253.2 PVD30231.1 - 0.012 16.7 0.8 0.012 16.7 0.8 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5320) TPR_MLP1_2 PF07926.12 PVD30231.1 - 0.018 15.1 1.6 0.018 15.1 1.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.12 PVD30231.1 - 0.025 14.7 0.3 0.025 14.7 0.3 2.4 2 1 1 3 3 3 0 MbeD/MobD like EAP30 PF04157.16 PVD30231.1 - 0.038 13.3 0.3 0.038 13.3 0.3 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family YabA PF06156.13 PVD30231.1 - 0.083 13.5 2.9 0.15 12.7 0.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 PVD30231.1 - 0.089 13.1 0.7 0.089 13.1 0.7 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 PVD30231.1 - 0.11 11.8 7.3 0.16 11.3 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nuc_deoxyrib_tr PF05014.15 PVD30231.1 - 0.17 11.9 0.7 0.32 11.0 0.7 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Cnn_1N PF07989.11 PVD30231.1 - 0.25 11.5 2.0 0.43 10.8 0.2 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 PVD30231.1 - 0.32 11.2 5.0 0.81 10.0 0.6 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 PVD30231.1 - 0.65 10.9 4.6 1.4 9.9 0.7 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain NRBF2 PF08961.10 PVD30231.1 - 1.1 8.9 4.3 0.26 10.9 0.8 1.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator KfrA_N PF11740.8 PVD30231.1 - 2.6 8.7 16.7 4.6 8.0 1.4 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term bZIP_2 PF07716.15 PVD30231.1 - 3.3 7.9 13.6 0.25 11.4 2.6 3.1 2 1 1 3 3 3 0 Basic region leucine zipper ZapB PF06005.12 PVD30231.1 - 4.7 7.7 15.5 1.3e+02 3.1 15.5 2.4 1 1 0 1 1 1 0 Cell division protein ZapB TFIIA PF03153.13 PVD30231.1 - 5.4 6.9 15.8 6.5 6.6 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADIP PF11559.8 PVD30231.1 - 6.7 6.8 11.6 0.39 10.8 1.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2457 PF10446.9 PVD30233.1 - 2.4e-06 27.0 17.9 2.8e-06 26.7 17.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 PVD30233.1 - 0.00016 20.1 19.5 0.00019 19.9 19.5 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 PVD30233.1 - 0.00025 21.3 16.4 0.00031 20.9 16.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 PVD30233.1 - 0.0067 14.7 21.1 0.0075 14.6 21.1 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 PVD30233.1 - 0.011 15.2 22.5 0.013 14.9 22.5 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 PVD30233.1 - 0.046 12.3 15.5 0.049 12.2 15.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 PVD30233.1 - 0.061 12.7 15.4 0.068 12.5 15.4 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 PVD30233.1 - 0.15 10.2 33.4 0.2 9.7 33.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 PVD30233.1 - 0.25 9.9 18.1 0.27 9.8 18.1 1.1 1 0 0 1 1 1 0 Utp14 protein RPN2_C PF18004.1 PVD30233.1 - 0.25 11.3 7.9 0.32 10.9 7.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 PVD30233.1 - 0.33 10.3 17.6 0.44 9.9 17.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.11 PVD30233.1 - 0.84 8.0 15.1 0.88 7.9 15.1 1.2 1 0 0 1 1 1 0 SGT1 protein TRM13 PF05206.14 PVD30233.1 - 1.1 8.7 10.6 5.2 6.5 10.3 1.9 1 1 1 2 2 2 0 Methyltransferase TRM13 DUF3295 PF11702.8 PVD30233.1 - 2.2 7.6 16.9 2.7 7.2 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RPA43_OB PF17875.1 PVD30233.1 - 2.6 8.7 6.0 3.7 8.2 6.0 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RNA_pol_Rpc4 PF05132.14 PVD30233.1 - 2.8 8.4 5.5 4.4 7.7 5.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pes-10 PF07149.11 PVD30233.1 - 3.6 6.5 16.9 3.9 6.4 16.9 1.2 1 0 0 1 1 1 0 Pes-10 Roughex PF06020.11 PVD30233.1 - 5.7 5.9 13.0 7.4 5.6 13.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC27 PF09507.10 PVD30233.1 - 9 5.6 21.2 11 5.3 21.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CoaE PF01121.20 PVD30234.1 - 1.1e-57 194.6 0.0 1.4e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 PVD30234.1 - 0.0078 16.8 0.0 0.05 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD30234.1 - 0.018 15.2 0.0 0.13 12.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain TT1725 PF18324.1 PVD30234.1 - 0.096 12.8 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Hypothetical protein TT1725 RRM_1 PF00076.22 PVD30235.1 - 0.0042 16.9 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMT_C PF02799.15 PVD30236.1 - 2.2e-39 135.2 1.2 2.6e-20 72.9 1.0 2.2 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Presenilin PF01080.17 PVD30236.1 - 0.4 9.4 1.5 0.46 9.2 1.5 1.2 1 0 0 1 1 1 0 Presenilin EF-hand_1 PF00036.32 PVD30238.1 - 9.3e-13 46.7 0.9 2e-06 26.9 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PVD30238.1 - 5.7e-12 45.9 8.3 7.3e-12 45.6 3.3 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD30238.1 - 3.9e-11 41.9 1.3 5.2e-06 26.0 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PVD30238.1 - 2.7e-07 30.3 2.0 0.0064 16.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD30238.1 - 2.8e-07 29.7 1.5 4.9e-05 22.6 0.0 3.2 4 0 0 4 4 4 1 EF hand DUF773 PF05600.12 PVD30238.1 - 0.027 13.2 0.0 0.031 13.0 0.0 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 EF-hand_9 PF14658.6 PVD30238.1 - 0.056 13.8 1.4 0.58 10.5 0.5 2.4 2 0 0 2 2 2 0 EF-hand domain Sugar_tr PF00083.24 PVD30239.1 - 3.1e-96 323.0 21.3 3.8e-96 322.7 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD30239.1 - 5e-33 114.5 47.6 1.5e-31 109.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PVD30239.1 - 1.8e-06 26.5 9.0 1.5e-05 23.5 3.6 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 PVD30239.1 - 3.9e-05 23.1 3.3 3.9e-05 23.1 3.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FAP206 PF12018.8 PVD30240.1 - 1.6e-101 339.5 5.9 2.8e-101 338.7 5.9 1.4 1 0 0 1 1 1 1 Domain of unknown function Calc_CGRP_IAPP PF00214.19 PVD30240.1 - 0.26 11.7 1.1 6.8 7.1 0.1 3.2 3 1 1 4 4 4 0 Calcitonin / CGRP / IAPP family DOCK_N PF16172.5 PVD30241.1 - 4.8e-91 305.5 0.3 1e-90 304.4 0.3 1.6 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 PVD30241.1 - 8.5e-53 179.8 9.2 1.7e-32 112.8 0.5 3.0 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 PVD30241.1 - 3e-49 167.5 0.1 2e-48 164.8 0.1 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 PVD30241.1 - 1.1e-07 31.6 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD30241.1 - 2.1e-07 30.4 0.2 6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PVD30241.1 - 1.5e-05 24.6 0.1 6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain VHP PF02209.19 PVD30242.1 - 8e-14 51.4 1.8 1.5e-13 50.6 1.8 1.5 1 0 0 1 1 1 1 Villin headpiece domain PAC1 PF16094.5 PVD30242.1 - 0.16 11.1 2.3 0.24 10.5 2.3 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 GST_N_4 PF17172.4 PVD30243.1 - 1.9e-28 99.1 0.0 3.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PVD30243.1 - 1.3e-20 73.0 0.0 2.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PVD30243.1 - 2.6e-10 40.7 0.0 3.6e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 PVD30243.1 - 1.3e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD30243.1 - 0.00027 21.1 0.0 0.0007 19.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD30243.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lambda_Kil PF06301.11 PVD30244.1 - 0.19 11.4 1.1 0.31 10.7 0.2 1.7 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein SNF PF00209.18 PVD30245.1 - 0.006 15.3 0.0 0.0074 15.0 0.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CARD_2 PF16739.5 PVD30246.1 - 7.2e-10 38.7 0.3 1.8e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 PVD30246.1 - 0.0089 16.2 0.1 0.057 13.6 0.0 2.3 3 0 0 3 3 3 1 Death domain CARD_2 PF16739.5 PVD30247.1 - 1.4e-07 31.4 0.4 8.9e-07 28.8 0.1 2.5 3 0 0 3 3 3 1 Caspase recruitment domain CARD_2 PF16739.5 PVD30248.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Caspase recruitment domain BORG_CEP PF14957.6 PVD30248.1 - 0.11 13.7 10.5 0.077 14.2 6.7 2.1 2 0 0 2 2 2 0 Cdc42 effector Anillin PF08174.11 PVD30250.1 - 2.2e-47 161.0 0.0 3.4e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 PVD30250.1 - 1.4e-12 48.0 0.4 4.3e-12 46.5 0.1 1.9 2 0 0 2 2 2 1 PH domain HR1 PF02185.16 PVD30250.1 - 9.7e-06 25.6 1.3 2e-05 24.6 1.3 1.5 1 0 0 1 1 1 1 Hr1 repeat DASH_Ask1 PF08655.10 PVD30250.1 - 0.12 12.2 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Ask1 F-box-like PF12937.7 PVD30252.1 - 8.9e-08 31.9 1.4 2.1e-07 30.7 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD30252.1 - 0.00026 20.8 0.3 0.00065 19.5 0.3 1.6 1 0 0 1 1 1 1 F-box domain Ion_trans_2 PF07885.16 PVD30253.1 - 4.6e-37 125.8 31.1 2e-19 69.3 2.2 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 PVD30253.1 - 1.4e-06 27.7 16.8 0.00047 19.5 1.1 2.3 2 0 0 2 2 2 2 Ion transport protein DUF883 PF05957.13 PVD30253.1 - 0.021 15.4 1.2 0.021 15.4 1.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2451 PF10474.9 PVD30253.1 - 0.043 13.6 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) IRK PF01007.20 PVD30253.1 - 0.39 10.5 0.1 0.39 10.5 0.1 3.1 3 1 1 4 4 4 0 Inward rectifier potassium channel transmembrane domain DUF2393 PF09624.10 PVD30253.1 - 1.2 9.1 5.5 0.13 12.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) OAD_gamma PF04277.13 PVD30253.1 - 8.6 7.0 8.4 1.1 10.0 0.4 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SAD_SRA PF02182.17 PVD30254.1 - 6.6e-59 198.1 0.3 1.4e-58 197.0 0.3 1.5 1 0 0 1 1 1 1 SAD/SRA domain TTD PF12148.8 PVD30254.1 - 2.1e-53 180.3 0.6 4.6e-53 179.3 0.6 1.5 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 ubiquitin PF00240.23 PVD30254.1 - 1.7e-13 50.1 0.5 3.5e-13 49.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family PHD PF00628.29 PVD30254.1 - 6.8e-12 45.1 12.0 6.8e-12 45.1 12.0 3.5 3 1 0 3 3 1 1 PHD-finger zf-C3HC4_2 PF13923.6 PVD30254.1 - 1e-06 28.5 12.9 1e-06 28.5 12.9 3.4 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PVD30254.1 - 7e-06 25.8 4.4 7e-06 25.8 4.4 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 PVD30254.1 - 8.7e-06 25.8 15.2 8.7e-06 25.8 15.2 3.4 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD30254.1 - 7.2e-05 22.6 15.1 7.2e-05 22.6 15.1 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD30254.1 - 0.00011 22.0 10.9 0.00011 22.0 10.9 4.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD30254.1 - 0.0007 19.9 13.1 0.0007 19.9 13.1 3.3 2 1 1 3 3 3 2 Ring finger domain Rad60-SLD PF11976.8 PVD30254.1 - 0.0013 18.6 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_5 PF14634.6 PVD30254.1 - 0.0028 17.6 13.0 0.0028 17.6 13.0 3.4 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD30254.1 - 0.0049 16.9 11.3 0.0049 16.9 11.3 3.2 2 1 0 2 2 1 1 RING-type zinc-finger Agenet PF05641.12 PVD30254.1 - 0.0093 16.4 0.0 1.6 9.3 0.0 2.8 2 0 0 2 2 2 1 Agenet domain Zona_pellucida PF00100.23 PVD30257.1 - 3.3e-09 36.9 0.0 4.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain WBP-1 PF11669.8 PVD30259.1 - 0.00011 22.8 7.8 0.00064 20.3 6.0 2.2 1 1 1 2 2 2 1 WW domain-binding protein 1 KSHV_K1 PF11049.8 PVD30259.1 - 0.057 13.4 2.1 0.11 12.5 2.1 1.4 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus TMEM52 PF14979.6 PVD30259.1 - 1.7 8.5 8.3 41 4.1 8.3 2.2 1 1 0 1 1 1 0 Transmembrane 52 AlbA_2 PF04326.14 PVD30260.1 - 1.3e-09 38.4 0.0 4.2e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Putative DNA-binding domain AAA_12 PF13087.6 PVD30261.1 - 0.00063 19.4 0.0 0.003 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PVD30261.1 - 0.012 15.5 0.1 0.043 13.6 0.0 2.0 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 PVD30261.1 - 0.043 13.2 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SH3_9 PF14604.6 PVD30262.1 - 5.4e-18 64.6 0.1 1.1e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD30262.1 - 8.2e-17 60.5 0.2 1.6e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD30262.1 - 1.8e-14 53.2 0.0 3.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 PVD30262.1 - 6.8e-13 48.7 0.1 6.8e-13 48.7 0.1 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 PVD30262.1 - 0.0027 17.3 6.0 0.0027 17.3 6.0 1.8 2 0 0 2 2 2 1 Vps5 C terminal like HR1 PF02185.16 PVD30262.1 - 0.0067 16.5 6.3 0.034 14.3 0.2 2.8 2 0 0 2 2 2 1 Hr1 repeat betaPIX_CC PF16523.5 PVD30262.1 - 0.026 14.3 2.5 0.05 13.4 0.1 2.7 2 1 0 2 2 2 0 betaPIX coiled coil HGAL PF15666.5 PVD30262.1 - 0.059 13.5 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Germinal center-associated lymphoma HD_assoc PF13286.6 PVD30262.1 - 0.43 11.1 4.0 0.55 10.8 0.5 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain PhaP_Bmeg PF09602.10 PVD30262.1 - 1.2 9.1 15.6 30 4.5 0.1 4.3 2 1 1 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TipAS PF07739.13 PVD30262.1 - 1.5 9.4 9.6 0.65 10.6 2.2 3.7 1 1 3 4 4 4 0 TipAS antibiotic-recognition domain CS PF04969.16 PVD30263.1 - 3.6e-06 27.9 0.0 5.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.27 PVD30264.1 - 4.4e-47 160.0 0.0 8.7e-23 81.4 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PVD30264.1 - 2.8e-20 72.2 1.1 2.8e-20 72.2 1.1 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 PVD30264.1 - 5.4e-20 72.4 4.1 5.8e-05 23.1 0.0 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD30264.1 - 2.6e-09 36.8 0.3 0.033 13.6 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PVD30264.1 - 2e-07 31.1 0.1 0.011 15.5 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PVD30264.1 - 2.6e-06 27.1 0.0 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 PVD30264.1 - 1.3e-05 25.3 0.1 0.23 11.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 PVD30264.1 - 2.9e-05 24.1 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD30264.1 - 5.1e-05 23.3 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 PVD30264.1 - 6.8e-05 23.4 0.0 0.12 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PVD30264.1 - 0.00011 22.7 0.0 0.44 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 PVD30264.1 - 0.00012 22.6 8.2 0.011 16.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 PVD30264.1 - 0.00012 22.3 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PVD30264.1 - 0.00075 19.8 0.0 0.62 10.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PVD30264.1 - 0.0057 16.7 0.2 0.88 9.6 0.0 3.0 3 0 0 3 3 2 1 Dynamin family NACHT PF05729.12 PVD30264.1 - 0.0074 16.2 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF2813 PF11398.8 PVD30264.1 - 0.0097 15.2 0.1 0.86 8.8 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA PF00004.29 PVD30264.1 - 0.01 16.2 0.1 1.9 8.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 PVD30264.1 - 0.015 14.9 0.7 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 PVD30264.1 - 0.017 15.2 0.0 6 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 PVD30264.1 - 0.017 14.8 0.0 0.74 9.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD30264.1 - 0.019 14.1 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 PVD30264.1 - 0.028 14.2 0.0 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 PVD30264.1 - 0.037 13.2 0.0 4.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MukB PF04310.12 PVD30264.1 - 0.039 13.7 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal AAA_5 PF07728.14 PVD30264.1 - 0.056 13.5 0.1 7.6 6.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PVD30264.1 - 0.073 12.6 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PVD30264.1 - 0.087 12.9 0.1 2.2 8.3 0.0 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_30 PF13604.6 PVD30264.1 - 0.09 12.5 0.0 1.2 8.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PVD30264.1 - 0.1 13.0 0.0 4 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 PVD30264.1 - 0.11 11.8 0.0 0.81 8.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 PVD30264.1 - 0.27 10.2 1.3 22 3.9 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UCH PF00443.29 PVD30265.1 - 1.4e-43 149.3 0.4 1.1e-37 129.9 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD30265.1 - 1.7e-21 77.2 4.5 1.8e-21 77.1 1.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 PVD30265.1 - 0.00065 20.1 0.0 0.0097 16.4 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 PVD30265.1 - 0.12 12.6 0.0 0.48 10.7 0.0 2.0 1 0 0 1 1 1 0 TUG ubiquitin-like domain KH_1 PF00013.29 PVD30266.1 - 5.5e-62 205.5 12.1 1e-15 57.3 0.0 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 PVD30266.1 - 2e-16 59.6 13.6 4e-05 23.4 0.5 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 PVD30266.1 - 5.3e-15 55.0 1.5 0.019 14.8 0.1 4.7 4 0 0 4 4 4 4 KH domain MOEP19 PF16005.5 PVD30266.1 - 6.7e-06 26.0 0.2 0.57 10.2 0.0 4.0 5 0 0 5 5 5 2 KH-like RNA-binding domain RRM_1 PF00076.22 PVD30266.1 - 7.1e-06 25.8 0.0 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.6 PVD30266.1 - 1.8e-05 24.7 12.8 0.15 12.1 0.2 4.4 4 0 0 4 4 4 4 NusA-like KH domain RRM_occluded PF16842.5 PVD30266.1 - 0.0042 16.9 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 Occluded RNA-recognition motif CooC_C PF15976.5 PVD30266.1 - 0.11 12.6 1.5 34 4.6 0.0 3.8 4 0 0 4 4 4 0 CS1-pili formation C-terminal Ras PF00071.22 PVD30267.1 - 1.3e-54 184.2 0.0 1.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD30267.1 - 5e-21 75.1 0.0 6.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD30267.1 - 3.6e-09 36.3 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD30267.1 - 8.6e-09 35.2 0.1 2.7e-08 33.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD30267.1 - 4.5e-05 23.4 0.0 0.051 13.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PVD30267.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD30267.1 - 0.00098 18.7 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 PVD30267.1 - 0.0011 18.4 0.1 0.0013 18.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PVD30267.1 - 0.0019 18.1 0.8 0.013 15.3 0.1 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 PVD30267.1 - 0.056 12.7 0.0 0.24 10.6 0.0 1.9 1 1 0 2 2 2 0 Septin AAA_16 PF13191.6 PVD30267.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 PVD30267.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 PVD30267.1 - 0.16 12.0 0.1 0.64 10.1 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase_Tyr PF07714.17 PVD30268.1 - 8e-77 258.0 0.0 1.8e-71 240.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase I-set PF07679.16 PVD30268.1 - 5.1e-41 138.6 0.0 8.6e-17 61.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD30268.1 - 2.4e-36 124.2 0.2 1.9e-12 47.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Pkinase PF00069.25 PVD30268.1 - 5.9e-36 124.2 0.1 9e-34 117.0 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain ig PF00047.25 PVD30268.1 - 8.2e-23 80.4 0.0 2.7e-07 30.6 0.0 3.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD30268.1 - 5.1e-21 74.8 0.1 3.1e-07 30.6 0.0 3.6 2 1 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD30268.1 - 2.2e-13 50.4 0.5 0.013 15.7 0.0 5.1 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD30268.1 - 1.3e-07 31.0 0.2 0.011 15.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 PVD30268.1 - 2.7e-07 30.9 0.0 0.087 13.2 0.0 3.5 2 1 1 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 PVD30268.1 - 7.2e-07 29.2 0.3 0.0043 17.1 0.0 3.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD30268.1 - 0.00024 21.1 0.0 1.6 8.9 0.0 3.6 2 1 1 3 3 3 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD30268.1 - 0.0015 18.8 0.0 2.5 8.4 0.0 3.4 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain 5_nucleotid PF05761.14 PVD30270.1 - 3.9e-147 490.9 0.5 4.6e-147 490.6 0.5 1.0 1 0 0 1 1 1 1 5' nucleotidase family JAKMIP_CC3 PF16034.5 PVD30271.1 - 1.3e-19 71.0 21.4 1.3e-19 71.0 21.4 24.0 7 6 12 19 19 19 1 JAKMIP CC3 domain SH3_2 PF07653.17 PVD30271.1 - 5.2e-08 32.5 0.0 0.00063 19.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PVD30271.1 - 3.6e-05 23.5 0.1 0.13 12.2 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PVD30271.1 - 0.026 14.1 0.0 6.1 6.5 0.0 2.8 2 0 0 2 2 2 0 SH3 domain Patatin PF01734.22 PVD30272.1 - 1.5e-27 97.2 0.0 2.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF5040 PF16443.5 PVD30272.1 - 0.0079 15.6 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5040) Acetyltransf_13 PF13880.6 PVD30275.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF1449 PF07290.11 PVD30276.1 - 0.024 14.2 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) EF-hand_7 PF13499.6 PVD30282.1 - 4.7e-16 59.0 0.2 8.7e-09 35.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD30282.1 - 3.2e-15 54.5 0.3 2.1e-06 26.9 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD30282.1 - 9.6e-13 47.0 0.3 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD30282.1 - 2.1e-10 39.6 0.2 0.00074 18.9 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD30282.1 - 5.6e-09 35.7 1.9 0.00047 19.9 0.2 2.7 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD30282.1 - 0.0025 18.1 0.3 0.16 12.3 0.0 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD30282.1 - 0.049 13.6 0.3 8.2 6.4 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand AAA_23 PF13476.6 PVD30283.1 - 0.016 15.8 6.8 0.016 15.8 6.8 2.6 2 1 0 2 2 2 0 AAA domain Luteo_PO PF04662.13 PVD30283.1 - 0.082 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Luteovirus P0 protein DUF2500 PF10694.9 PVD30283.1 - 0.42 11.1 1.9 45 4.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) Atg14 PF10186.9 PVD30283.1 - 0.58 9.2 9.0 1.4 8.0 9.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 PVD30283.1 - 3.7 7.4 17.4 0.042 13.7 3.9 3.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain MA3 PF02847.17 PVD30284.1 - 1.6e-46 156.9 0.4 4e-27 94.4 0.2 2.1 2 0 0 2 2 2 2 MA3 domain PNP_phzG_C PF10590.9 PVD30285.1 - 2.5e-20 72.3 0.5 4.1e-20 71.6 0.5 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region zf-4CXXC_R1 PF10497.9 PVD30286.1 - 9.5e-17 61.1 3.7 1.7e-16 60.3 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-FCS PF06467.14 PVD30286.1 - 0.067 13.1 5.3 0.14 12.1 5.3 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Endonuclease_7 PF02945.15 PVD30286.1 - 0.097 12.6 2.2 0.18 11.7 2.2 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII Xan_ur_permease PF00860.20 PVD30287.1 - 3.7e-69 233.3 10.7 1e-65 221.9 2.9 2.2 2 0 0 2 2 2 2 Permease family Xan_ur_permease PF00860.20 PVD30288.1 - 1.7e-63 214.7 22.3 6.6e-63 212.7 21.4 2.2 1 1 0 1 1 1 1 Permease family DUF2516 PF10724.9 PVD30288.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) MFS_MOT1 PF16983.5 PVD30288.1 - 5.9 7.3 18.2 0.87 10.0 2.1 3.5 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily EF-hand_1 PF00036.32 PVD30289.1 - 2.8e-23 79.7 12.3 9.1e-06 24.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD30289.1 - 6.8e-23 80.9 3.3 3e-11 43.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD30289.1 - 2.1e-21 74.4 8.7 6.6e-05 22.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD30289.1 - 1.2e-20 71.6 6.8 7.8e-05 22.3 0.2 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PVD30289.1 - 2e-17 62.8 9.5 2.2e-07 30.6 0.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD30289.1 - 9.6e-06 25.9 0.2 0.021 15.1 0.1 3.0 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD30289.1 - 0.0012 19.0 0.1 5.4 7.3 0.0 3.4 4 0 0 4 4 4 2 Dockerin type I domain EF-hand_4 PF12763.7 PVD30289.1 - 0.0046 16.9 0.2 0.11 12.4 0.0 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_13 PF17958.1 PVD30289.1 - 0.015 15.1 0.0 33 4.4 0.0 3.8 3 1 1 4 4 4 0 EF-hand domain DnaJ PF00226.31 PVD30290.1 - 5.1e-24 84.2 2.3 1.7e-23 82.5 2.3 2.0 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 PVD30290.1 - 2e-12 47.1 9.3 4.7e-07 29.9 0.3 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD30290.1 - 0.0066 16.7 9.1 0.09 13.0 0.0 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain OrsD PF12013.8 PVD30290.1 - 0.019 15.4 0.1 0.053 14.0 0.1 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D IFP_35_N PF07334.13 PVD30290.1 - 0.059 13.4 2.7 0.14 12.2 2.7 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus WBP-1 PF11669.8 PVD30290.1 - 0.17 12.5 0.4 3.2 8.4 0.0 2.9 3 0 0 3 3 3 0 WW domain-binding protein 1 Chitin_synth_2 PF03142.15 PVD30292.1 - 4.5e-23 81.7 16.6 1.3e-20 73.6 7.1 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD30292.1 - 1.8e-15 57.4 1.3 1.8e-15 57.4 1.3 3.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD30292.1 - 2.6e-06 27.5 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 PVD30293.1 - 6.9e-06 24.9 1.2 1.1e-05 24.3 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD30293.1 - 7.2e-05 22.8 0.1 7.2e-05 22.8 0.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD30293.1 - 0.037 13.9 1.5 0.084 12.7 1.6 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 PVD30294.1 - 0.009 14.7 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase 7TM_GPCR_Srw PF10324.9 PVD30297.1 - 4.4e-23 82.0 0.7 5.5e-23 81.7 0.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD30297.1 - 6.5e-06 25.7 0.1 8.3e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD30298.1 - 2.2e-10 40.3 9.0 2.2e-10 40.3 9.0 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD30298.1 - 1.4e-06 27.8 3.5 2.9e-06 26.8 3.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HSF_DNA-bind PF00447.17 PVD30299.1 - 1.6e-12 47.9 0.1 3.3e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PDZ PF00595.24 PVD30300.1 - 4.7e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD30300.1 - 2.1e-07 30.7 1.0 3.5e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD30300.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RBD PF02196.15 PVD30301.1 - 7.9e-31 106.0 0.0 9.5e-21 73.7 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 PVD30301.1 - 1.1e-29 103.1 0.5 3.3e-29 101.6 0.5 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain zf-tcix PF14952.6 PVD30302.1 - 6.9e-22 76.8 4.3 1.5e-21 75.7 4.3 1.6 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 PVD30302.1 - 0.035 13.6 1.7 0.08 12.4 1.7 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.6 PVD30302.1 - 0.66 9.5 3.3 0.58 9.6 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Snf7 PF03357.21 PVD30303.1 - 4.3e-21 75.3 10.1 1.1e-20 74.0 10.1 1.7 1 1 0 1 1 1 1 Snf7 DUF948 PF06103.11 PVD30303.1 - 0.0099 16.1 9.9 0.34 11.2 1.2 3.6 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) DUF1542 PF07564.11 PVD30303.1 - 0.82 9.8 4.6 1.1 9.4 0.0 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1542) Phage_integr_3 PF16795.5 PVD30303.1 - 2 8.3 6.7 3.5 7.5 0.6 2.3 1 1 1 2 2 2 0 Archaeal phage integrase FYVE PF01363.21 PVD30304.1 - 4.2e-21 74.9 9.7 4.2e-21 74.9 9.7 3.7 3 1 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 PVD30304.1 - 0.22 11.7 12.8 0.021 15.1 6.8 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger HOOK PF05622.12 PVD30305.1 - 5.7e-05 21.5 10.4 5.7e-05 21.5 10.4 2.1 1 1 1 2 2 2 1 HOOK protein CARD_2 PF16739.5 PVD30305.1 - 0.00011 22.1 2.4 0.00032 20.6 0.1 2.6 2 0 0 2 2 2 1 Caspase recruitment domain Spc7 PF08317.11 PVD30305.1 - 0.00059 18.8 8.3 0.00059 18.8 8.3 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Laminin_II PF06009.12 PVD30305.1 - 0.0055 16.7 14.9 0.0055 16.7 14.9 3.2 2 1 1 3 3 3 1 Laminin Domain II MAD PF05557.13 PVD30305.1 - 0.0058 15.1 35.7 0.015 13.7 6.8 2.3 1 1 1 2 2 2 2 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 PVD30305.1 - 0.0065 16.4 12.3 0.0065 16.4 12.3 4.0 2 1 2 4 4 4 2 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 PVD30305.1 - 0.015 14.5 32.7 0.023 13.9 32.7 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF812 PF05667.11 PVD30305.1 - 0.031 13.2 37.0 0.067 12.1 37.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 PVD30305.1 - 0.045 13.8 40.3 0.032 14.2 5.3 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 PVD30305.1 - 0.091 12.5 33.3 0.11 12.2 31.7 1.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4763 PF15960.5 PVD30305.1 - 0.2 10.9 38.9 0.03 13.6 9.2 3.5 2 1 3 5 5 5 0 Domain of unknown function (DUF4763) TPR_MLP1_2 PF07926.12 PVD30305.1 - 0.21 11.7 39.7 1 9.4 31.0 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 PVD30305.1 - 0.23 11.7 28.8 0.36 11.1 27.7 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein FUSC PF04632.12 PVD30305.1 - 0.39 9.2 12.3 4 5.9 12.0 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family EzrA PF06160.12 PVD30305.1 - 0.45 8.6 27.8 0.048 11.8 7.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA MscS_porin PF12795.7 PVD30305.1 - 0.63 9.5 42.1 1.2 8.6 41.8 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain CALCOCO1 PF07888.11 PVD30305.1 - 0.75 8.6 39.8 0.45 9.3 37.2 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlgN PF05130.12 PVD30305.1 - 1.6 9.2 29.1 1.7 9.2 14.7 2.6 1 1 1 2 2 2 0 FlgN protein Rab5-bind PF09311.11 PVD30305.1 - 1.8 7.9 38.9 0.061 12.7 12.1 3.1 1 1 2 3 3 3 0 Rabaptin-like protein Tropomyosin_1 PF12718.7 PVD30305.1 - 2.1 8.5 37.4 0.27 11.4 12.6 2.5 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.11 PVD30305.1 - 2.1 8.5 40.4 5.9 7.1 32.5 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 PVD30305.1 - 3.2 7.3 42.6 0.047 13.4 3.4 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 PVD30305.1 - 3.8 7.3 40.0 0.58 9.9 29.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 PVD30305.1 - 5.5 7.2 40.6 1.3 9.2 29.1 2.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 PVD30305.1 - 5.7 5.9 37.1 1.4 7.9 12.7 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 PVD30305.1 - 8 6.9 26.5 0.26 11.6 6.4 4.7 2 1 3 5 5 5 0 TSC-22/dip/bun family BRE1 PF08647.11 PVD30305.1 - 9.2 6.4 39.8 1.4 9.1 11.5 3.5 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 PVD30305.1 - 9.2 5.6 40.0 11 5.4 31.7 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 PVD30305.1 - 9.4 7.2 40.5 66 4.5 16.5 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 PVD30305.1 - 9.8 5.5 40.9 1.9 7.8 24.1 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CARD PF00619.21 PVD30306.1 - 2.5e-07 30.6 0.1 2.5e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 PVD30306.1 - 1.4e-06 28.2 0.1 4.9e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 Caspase recruitment domain Tropomyosin PF00261.20 PVD30306.1 - 0.0029 17.0 25.3 0.0029 17.0 25.3 3.3 1 1 2 3 3 3 2 Tropomyosin Viral_DNA_Zn_bi PF03728.13 PVD30306.1 - 0.16 12.6 6.0 0.1 13.2 2.8 2.3 1 1 1 2 2 2 0 Viral DNA-binding protein, zinc binding domain DUF3584 PF12128.8 PVD30306.1 - 0.72 7.3 48.3 0.37 8.2 46.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Hemagglutinin PF00509.18 PVD30306.1 - 6.3 5.1 11.7 1.8 6.9 8.3 1.6 1 1 1 2 2 2 0 Haemagglutinin Ifi-6-16 PF06140.13 PVD30308.1 - 2.4e-33 113.9 96.0 1e-12 47.8 18.9 3.5 3 0 0 3 3 3 3 Interferon-induced 6-16 family IQ PF00612.27 PVD30308.1 - 8.7e-07 28.2 0.3 2.6e-06 26.7 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif CENP-N PF05238.13 PVD30308.1 - 0.00068 19.0 3.1 0.0012 18.3 3.1 1.4 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Pex14_N PF04695.13 PVD30308.1 - 0.00069 20.3 5.7 0.00069 20.3 5.7 2.5 3 0 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 PVD30308.1 - 0.0012 17.7 12.0 0.0012 17.7 12.0 1.8 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.11 PVD30308.1 - 0.0025 17.3 8.5 0.0062 16.0 8.4 1.6 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Paf1 PF03985.13 PVD30308.1 - 0.0054 15.8 25.5 0.0054 15.8 25.5 1.8 2 0 0 2 2 2 1 Paf1 Roughex PF06020.11 PVD30308.1 - 0.009 15.2 12.5 0.016 14.4 12.5 1.4 1 0 0 1 1 1 1 Drosophila roughex protein DUF5308 PF17233.2 PVD30308.1 - 0.02 15.2 8.1 0.05 13.8 5.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) MTP18 PF10558.9 PVD30308.1 - 0.027 14.4 0.4 0.078 12.9 0.4 1.9 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Sporozoite_P67 PF05642.11 PVD30308.1 - 0.027 12.6 22.3 0.15 10.1 22.4 1.9 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Ctr PF04145.15 PVD30308.1 - 0.099 13.3 7.9 0.1 13.2 4.3 2.6 2 0 0 2 2 2 0 Ctr copper transporter family SAPS PF04499.15 PVD30308.1 - 0.11 11.3 13.2 0.18 10.6 13.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Connexin PF00029.19 PVD30308.1 - 0.12 12.1 17.8 0.029 14.1 13.7 2.0 2 0 0 2 2 2 0 Connexin Otopetrin PF03189.13 PVD30308.1 - 0.13 11.1 0.4 0.21 10.3 0.4 1.4 1 0 0 1 1 1 0 Otopetrin GREB1 PF15782.5 PVD30308.1 - 0.17 9.0 8.4 0.22 8.6 8.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_11 PF13086.6 PVD30308.1 - 0.25 11.1 21.0 0.032 14.0 16.7 1.6 2 0 0 2 2 1 0 AAA domain FancD2 PF14631.6 PVD30308.1 - 0.26 8.7 15.6 0.38 8.1 15.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Gti1_Pac2 PF09729.9 PVD30308.1 - 0.28 11.2 17.0 0.5 10.4 14.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Spt20 PF12090.8 PVD30308.1 - 0.31 10.6 19.9 0.54 9.8 19.9 1.3 1 0 0 1 1 1 0 Spt20 family SID-1_RNA_chan PF13965.6 PVD30308.1 - 0.37 9.1 4.0 0.59 8.5 4.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.12 PVD30308.1 - 0.42 10.9 17.1 0.34 11.1 11.7 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Serinc PF03348.15 PVD30308.1 - 0.45 9.4 8.4 0.88 8.4 8.4 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 PVD30308.1 - 0.52 8.4 15.9 0.84 7.7 15.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RPOL_N PF14700.6 PVD30308.1 - 0.68 9.3 24.9 0.031 13.7 16.3 2.6 3 0 0 3 3 2 0 DNA-directed RNA polymerase N-terminal DNA_pol_phi PF04931.13 PVD30308.1 - 0.88 7.6 25.0 1.5 6.8 25.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 PVD30308.1 - 1 8.3 13.6 0.24 10.3 10.4 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 PVD30308.1 - 1 9.1 34.5 0.026 14.4 27.2 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 PVD30308.1 - 1.5 8.9 32.6 0.4 10.8 27.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4776 PF16003.5 PVD30308.1 - 1.6 7.6 20.3 0.19 10.7 16.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) Nop53 PF07767.11 PVD30308.1 - 1.7 8.0 35.7 0.26 10.6 30.1 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) AAA_23 PF13476.6 PVD30308.1 - 1.8 9.0 26.0 3.3 8.1 26.0 1.5 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.16 PVD30308.1 - 1.9 7.9 25.8 1 8.8 23.4 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 RRN3 PF05327.11 PVD30308.1 - 2 6.9 12.7 3.3 6.1 12.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PNISR PF15996.5 PVD30308.1 - 2 8.6 33.7 1.4 9.2 28.4 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RNA_pol_Rpc4 PF05132.14 PVD30308.1 - 2.8 8.3 21.7 0.047 14.1 13.1 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Endostatin PF06482.11 PVD30308.1 - 3.7 6.9 11.0 7 6.0 11.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2370 PF10176.9 PVD30308.1 - 3.7 7.1 6.7 7.8 6.1 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TP53IP5 PF15331.6 PVD30308.1 - 4 7.5 16.2 1 9.5 12.6 1.7 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 XRN_M PF17846.1 PVD30308.1 - 6.6 5.6 15.2 11 4.8 15.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain NARP1 PF12569.8 PVD30308.1 - 6.7 5.5 27.8 13 4.6 27.8 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.12 PVD30308.1 - 9.6 5.0 19.8 15 4.4 19.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3807 PF12720.7 PVD30308.1 - 9.9 6.4 33.5 4.2 7.6 28.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Ifi-6-16 PF06140.13 PVD30309.1 - 3.4e-11 42.9 24.0 5.1e-11 42.3 20.7 2.5 2 0 0 2 2 2 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 PVD30310.1 - 1.8e-08 34.2 31.8 3e-08 33.5 31.8 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 PVD30311.1 - 0.0026 17.6 18.0 0.0039 17.1 18.0 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ig_3 PF13927.6 PVD30313.1 - 2.8e-58 194.4 20.4 1.8e-14 54.1 0.1 6.2 6 0 0 6 6 5 5 Immunoglobulin domain I-set PF07679.16 PVD30313.1 - 5.9e-56 186.5 16.5 2.7e-16 59.4 0.0 6.8 8 1 0 8 8 8 4 Immunoglobulin I-set domain fn3 PF00041.21 PVD30313.1 - 8.7e-43 144.6 10.8 3e-09 37.1 0.3 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 PVD30313.1 - 8.2e-39 131.8 18.1 1.2e-10 41.5 0.0 6.1 5 1 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 PVD30313.1 - 4.5e-36 122.9 6.4 3.8e-08 33.4 0.1 6.2 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 PVD30313.1 - 9.8e-16 57.9 16.4 0.0016 18.6 0.0 8.4 5 4 1 7 7 7 5 Immunoglobulin V-set domain Bravo_FIGEY PF13882.6 PVD30313.1 - 6.6e-10 40.2 4.5 6.6e-10 40.2 4.5 3.1 3 1 0 3 3 1 1 Bravo-like intracellular region C2-set_2 PF08205.12 PVD30313.1 - 1.9e-06 27.9 6.0 0.016 15.3 0.0 5.1 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain DUF2207 PF09972.9 PVD30313.1 - 1.9e-06 26.9 0.1 6e-05 22.0 0.0 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Ig_6 PF18452.1 PVD30313.1 - 2e-06 27.3 0.0 0.22 11.1 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Herpes_gE PF02480.16 PVD30313.1 - 0.00012 21.0 0.1 4 6.1 0.0 4.3 3 1 1 5 5 5 2 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 PVD30313.1 - 0.00017 21.5 0.4 1.8 8.6 0.0 3.8 3 1 0 3 3 3 2 C17orf99 Ig domain Interfer-bind PF09294.10 PVD30313.1 - 0.00049 20.4 4.2 3.5 8.0 0.0 5.9 6 1 1 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.15 PVD30313.1 - 0.00053 20.1 1.6 4 7.7 0.0 4.2 4 0 0 4 4 3 1 Immunoglobulin C2-set domain Ig_4 PF16680.5 PVD30313.1 - 0.0012 19.0 6.1 3.9 7.8 0.1 4.9 5 1 0 5 5 4 1 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 PVD30313.1 - 0.0014 18.6 0.0 5.7 7.1 0.0 4.1 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family DUF4870 PF09685.10 PVD30313.1 - 0.018 15.2 0.6 0.018 15.2 0.6 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4870) Hum_adeno_E3A PF05393.11 PVD30313.1 - 0.048 13.6 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein ASFV_J13L PF05568.11 PVD30313.1 - 0.062 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 African swine fever virus J13L protein MFS_2 PF13347.6 PVD30313.1 - 0.087 11.4 0.0 0.087 11.4 0.0 1.6 2 0 0 2 2 2 0 MFS/sugar transport protein Pur_ac_phosph_N PF16656.5 PVD30313.1 - 0.1 13.2 5.7 0.4 11.3 0.1 4.5 5 0 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain LRR19-TM PF15176.6 PVD30313.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ATG27 PF09451.10 PVD30313.1 - 0.12 12.2 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 27 DUF3784 PF12650.7 PVD30313.1 - 8.3 6.7 10.3 0.051 13.8 1.5 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF3784) Abhydrolase_6 PF12697.7 PVD30314.1 - 3.9e-05 24.4 0.2 0.00015 22.5 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD30314.1 - 0.0015 18.2 0.0 0.0039 16.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PVD30314.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PVD30314.1 - 0.0042 16.4 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 PVD30314.1 - 0.051 13.1 0.1 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Pkinase_Tyr PF07714.17 PVD30315.1 - 5.3e-59 199.6 0.1 8.2e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD30315.1 - 1e-56 192.3 0.0 1.7e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 PVD30315.1 - 1.5e-18 66.6 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 PVD30315.1 - 3.4e-11 42.9 5.0 6.6e-11 41.9 5.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 PVD30315.1 - 1.2e-08 34.6 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 PVD30315.1 - 3.2e-05 24.1 5.6 8.6e-05 22.8 5.6 1.8 1 0 0 1 1 1 1 RING-like domain Pkinase_fungal PF17667.1 PVD30315.1 - 0.00096 18.0 0.2 0.0016 17.3 0.2 1.6 1 1 0 1 1 1 1 Fungal protein kinase DUF812 PF05667.11 PVD30315.1 - 0.012 14.6 1.1 0.024 13.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Kdo PF06293.14 PVD30315.1 - 0.022 14.1 0.7 0.041 13.2 0.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TUG-UBL1 PF11470.8 PVD30315.1 - 0.03 14.6 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 TUG ubiquitin-like domain APH PF01636.23 PVD30315.1 - 0.06 13.3 0.0 0.19 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_2 PF03107.16 PVD30315.1 - 0.11 12.9 2.5 0.33 11.3 2.5 1.9 1 0 0 1 1 1 0 C1 domain OmpH PF03938.14 PVD30315.1 - 0.82 10.0 3.3 1.6 9.1 3.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PHD PF00628.29 PVD30315.1 - 1 9.3 4.9 2.7 8.0 4.9 1.7 1 0 0 1 1 1 0 PHD-finger DHR10 PF18595.1 PVD30315.1 - 2.5 8.2 7.5 12 5.9 7.5 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TMEM154 PF15102.6 PVD30317.1 - 0.0003 20.7 0.3 0.0003 20.7 0.3 3.6 1 1 2 3 3 2 1 TMEM154 protein family SKG6 PF08693.10 PVD30317.1 - 0.00065 19.0 10.1 0.0021 17.4 10.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 PVD30317.1 - 0.0015 18.5 0.2 0.0026 17.7 0.2 1.3 1 0 0 1 1 1 1 Rifin Collectrin PF16959.5 PVD30317.1 - 0.0086 15.9 2.1 0.016 15.0 2.1 1.4 1 0 0 1 1 1 1 Renal amino acid transporter DUF2569 PF10754.9 PVD30317.1 - 0.011 16.2 0.1 0.07 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4519 PF15012.6 PVD30317.1 - 0.053 13.7 2.1 0.086 13.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Orf78 PF06024.12 PVD30317.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF3377 PF11857.8 PVD30317.1 - 0.057 13.4 0.6 0.1 12.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF5305 PF17231.2 PVD30317.1 - 0.059 12.8 0.3 0.11 11.9 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 PVD30317.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 PVD30317.1 - 0.08 13.8 0.1 0.21 12.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 PVD30317.1 - 0.26 11.1 8.1 0.47 10.3 8.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 PVD30317.1 - 6.8 6.7 5.5 12 5.9 5.5 1.3 1 0 0 1 1 1 0 Syndecan domain Globin PF00042.22 PVD30319.1 - 1e-07 32.5 1.0 4.6e-07 30.4 0.3 1.9 1 1 1 2 2 2 2 Globin EGF PF00008.27 PVD30321.1 - 1.9e-05 24.9 8.3 4.8e-05 23.6 8.3 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 PVD30321.1 - 0.00072 20.1 2.4 0.00072 20.1 2.4 2.9 3 0 0 3 3 3 1 Human growth factor-like EGF cEGF PF12662.7 PVD30321.1 - 1.6 8.8 5.5 2.2 8.3 4.0 2.2 2 1 0 2 2 2 0 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD30321.1 - 1.6 9.0 5.4 4.4 7.6 5.4 1.8 1 0 0 1 1 1 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 PVD30321.1 - 9.2 6.5 11.3 6.7 6.9 7.5 2.5 2 1 0 2 2 2 0 Laminin EGF domain Kelch_1 PF01344.25 PVD30322.1 - 4.9e-67 221.3 12.3 2.7e-17 62.0 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD30322.1 - 1.2e-41 139.6 8.0 1.4e-09 37.9 0.0 6.5 2 1 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD30322.1 - 7.4e-29 98.6 7.7 5.9e-08 32.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 PVD30322.1 - 5.6e-27 94.2 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 PVD30322.1 - 6.4e-23 80.5 8.3 0.00035 20.5 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 PVD30322.1 - 5.9e-21 74.5 1.0 2.1e-20 72.7 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 PVD30322.1 - 1.9e-18 66.3 10.8 4.3e-07 30.0 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD30322.1 - 7.2e-14 51.4 11.0 0.00067 19.6 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Forkhead PF00250.18 PVD30323.1 - 1.7e-12 47.4 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Herpes_LMP1 PF05297.11 PVD30323.1 - 5.1 6.2 6.5 8.2 5.5 6.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ras PF00071.22 PVD30324.1 - 1.8e-93 310.5 0.0 1.8e-54 183.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PVD30324.1 - 9.9e-40 135.5 0.0 1.1e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD30324.1 - 6.9e-15 54.9 0.0 2.6e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD30324.1 - 8.7e-08 31.9 0.0 0.00086 18.9 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD30324.1 - 0.0032 16.9 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MeaB PF03308.16 PVD30324.1 - 0.0048 15.9 0.2 0.46 9.4 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB LAG1-DNAbind PF09271.11 PVD30324.1 - 0.0086 16.7 0.4 0.93 10.1 0.2 2.2 2 0 0 2 2 2 1 LAG1, DNA binding PK_C PF02887.16 PVD30324.1 - 0.057 13.7 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain SRPRB PF09439.10 PVD30324.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit VASP_tetra PF08776.11 PVD30324.1 - 0.091 12.3 5.3 2.1 8.0 0.4 2.5 2 0 0 2 2 2 0 VASP tetramerisation domain Ldh_1_N PF00056.23 PVD30324.1 - 0.17 12.0 0.0 89 3.2 0.0 3.1 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.7 PVD30325.1 - 6.5e-35 120.5 0.0 1.1e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PVD30325.1 - 8.3e-09 35.5 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD30325.1 - 0.021 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4371 PF14291.6 PVD30325.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Pkinase PF00069.25 PVD30327.1 - 2.7e-63 213.8 0.0 3.4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30327.1 - 7.6e-37 127.0 0.0 1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD30327.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PVD30327.1 - 6.4e-07 29.1 0.2 9.3e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PVD30327.1 - 2.9e-06 26.8 1.3 7.4e-06 25.5 1.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD30327.1 - 1.5e-05 24.1 0.7 2.1e-05 23.7 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD30327.1 - 0.002 18.1 0.2 0.015 15.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD30327.1 - 0.014 14.2 0.3 0.029 13.2 0.3 1.3 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PVD30327.1 - 0.088 12.4 0.4 0.24 11.0 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 PVD30327.1 - 0.19 11.3 1.0 4.8 6.7 0.3 2.4 1 1 1 2 2 2 0 Choline/ethanolamine kinase WH1 PF00568.23 PVD30328.1 - 7.6e-31 106.3 0.3 1.2e-30 105.7 0.3 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 PVD30328.1 - 5.9e-14 51.4 4.5 2.6e-06 27.0 0.1 3.0 2 0 0 2 2 2 2 WH2 motif Sacchrp_dh_C PF16653.5 PVD30329.1 - 2.9e-51 175.1 0.2 4.4e-30 105.7 0.1 2.1 1 1 1 2 2 2 2 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 PVD30329.1 - 9.1e-07 29.2 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 PVD30330.1 - 1.1e-57 196.1 0.0 5.6e-57 193.9 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Ldl_recept_a PF00057.18 PVD30330.1 - 6e-12 45.6 10.0 1.3e-11 44.5 10.0 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Vwaint PF14624.6 PVD30330.1 - 0.69 10.1 2.9 4.7 7.4 0.1 2.7 3 0 0 3 3 3 0 VWA / Hh protein intein-like Ldl_recept_a PF00057.18 PVD30331.1 - 4e-14 52.5 32.4 2.5e-11 43.6 13.2 3.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD30332.1 - 4.1e-21 74.9 35.3 1.1e-10 41.5 16.6 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Toxin_23 PF08093.11 PVD30332.1 - 3.8 7.7 16.6 2.6 8.3 0.5 4.7 3 1 1 4 4 4 0 Magi 5 toxic peptide family Ldl_recept_a PF00057.18 PVD30333.1 - 0.035 14.3 0.2 0.071 13.3 0.2 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD30334.1 - 9.7e-19 67.3 30.9 5.7e-13 48.8 11.6 3.1 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRA PF18491.1 PVD30334.1 - 0.17 12.0 0.0 21 5.2 0.0 2.2 2 0 0 2 2 2 0 SET and RING associated domain Ldl_recept_a PF00057.18 PVD30335.1 - 1.5e-38 130.7 65.1 5.3e-13 48.9 12.7 4.1 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD30336.1 - 6.7e-35 119.0 52.2 2.7e-12 46.7 10.6 3.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD30337.1 - 8.9e-196 633.8 358.3 1.4e-12 47.6 13.0 19.3 19 0 0 19 19 19 19 Low-density lipoprotein receptor domain class A DUF3357 PF11837.8 PVD30337.1 - 0.00086 19.7 1.0 14 6.2 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3357) ABC_membrane_2 PF06472.15 PVD30337.1 - 2.3 7.6 5.9 66 2.8 0.0 3.6 4 0 0 4 4 4 0 ABC transporter transmembrane region 2 DUF3290 PF11694.8 PVD30337.1 - 2.9 7.9 6.6 89 3.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3290) UPF0242 PF06785.11 PVD30337.1 - 5.8 7.0 5.3 1.7e+02 2.2 0.1 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Pentapeptide_4 PF13599.6 PVD30338.1 - 2e-33 114.4 25.6 5.1e-05 23.4 0.4 9.2 3 1 7 10 10 10 8 Pentapeptide repeats (9 copies) MIEAP PF16026.5 PVD30339.1 - 1.4e-48 165.8 0.1 7.2e-48 163.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondria-eating protein DivIC PF04977.15 PVD30339.1 - 0.71 9.7 2.5 0.8 9.5 1.0 1.8 2 0 0 2 2 2 0 Septum formation initiator CCDC142 PF14923.6 PVD30340.1 - 1.5e-73 248.1 8.7 2.1e-73 247.6 8.7 1.1 1 0 0 1 1 1 1 Coiled-coil protein 142 DUF3984 PF13136.6 PVD30340.1 - 0.018 14.5 0.3 0.028 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DNA_pol_B_palm PF14792.6 PVD30341.1 - 3.4e-12 46.6 0.1 1.4e-11 44.6 0.0 2.0 2 1 0 2 2 2 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 PVD30341.1 - 0.0039 17.4 0.0 0.03 14.6 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain DNA_pol_lambd_f PF10391.9 PVD30341.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 PVD30342.1 - 1.2e-05 25.4 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb 7tm_1 PF00001.21 PVD30343.1 - 6.2e-09 35.6 8.8 8e-09 35.2 8.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CT47 PF15623.6 PVD30344.1 - 0.047 13.5 0.1 0.054 13.3 0.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Menin PF05053.13 PVD30345.1 - 0.0046 15.4 3.8 0.0053 15.2 3.8 1.1 1 0 0 1 1 1 1 Menin Stevor PF17410.2 PVD30345.1 - 0.0071 15.9 2.4 0.0092 15.6 2.4 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 PVD30345.1 - 0.13 12.6 0.9 0.21 11.9 0.9 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF3464 PF11947.8 PVD30345.1 - 0.32 10.7 1.0 0.45 10.3 1.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4834 PF16118.5 PVD30345.1 - 1.3 10.0 4.3 1.9 9.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) 7tm_1 PF00001.21 PVD30346.1 - 8.9e-07 28.5 0.7 1.6e-06 27.7 0.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30346.1 - 0.015 14.7 1.3 0.023 14.1 1.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Rcd1 PF04078.13 PVD30347.1 - 2.6e-127 423.5 2.0 3.4e-127 423.1 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like APG9 PF04109.16 PVD30348.1 - 1e-166 555.7 18.9 1.2e-166 555.5 18.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.24 PVD30348.1 - 0.11 12.5 0.9 0.17 11.8 0.3 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Abhydrolase_1 PF00561.20 PVD30349.1 - 2.1e-32 112.8 0.0 4.2e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD30349.1 - 7.8e-12 45.0 0.0 1.6e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD30349.1 - 7.5e-10 39.8 0.3 1e-09 39.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 PVD30349.1 - 0.00067 18.4 0.0 0.00097 17.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 PVD30349.1 - 0.0036 17.4 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 PVD30349.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 PVD30349.1 - 0.028 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 PVD30349.1 - 0.094 12.6 0.0 0.92 9.3 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase FAD_binding_7 PF03441.14 PVD30350.1 - 6.4e-76 254.3 1.1 9.3e-76 253.8 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PVD30350.1 - 2.9e-42 144.5 0.0 4.8e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Linker_histone PF00538.19 PVD30351.1 - 0.00032 21.0 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family Macoilin PF09726.9 PVD30354.1 - 0.7 8.4 10.2 0.76 8.3 10.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 PVD30354.1 - 1.8 7.8 6.8 2.8 7.2 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM117 PF15388.6 PVD30355.1 - 2.3e-51 175.1 14.4 3.1e-51 174.7 14.4 1.1 1 0 0 1 1 1 1 Protein Family FAM117 Rep_fac-A_3 PF08661.11 PVD30357.1 - 2.5e-19 69.6 0.0 2.7e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Mce4_CUP1 PF11887.8 PVD30357.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative zinc_ribbon_16 PF17034.5 PVD30358.1 - 7.7e-21 74.6 10.9 2.1e-20 73.2 10.9 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family DUF3134 PF11332.8 PVD30359.1 - 0.026 14.8 0.2 0.026 14.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) FUSC PF04632.12 PVD30359.1 - 0.53 8.7 20.0 0.54 8.7 8.7 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 PVD30359.1 - 0.56 10.6 57.9 1.2 9.5 13.8 3.2 1 1 2 3 3 3 0 Fez1 DUF3037 PF11236.8 PVD30359.1 - 1.1 9.7 20.2 1.7 9.1 4.6 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3037) TACC_C PF05010.14 PVD30359.1 - 2 8.2 60.6 1.4 8.6 37.1 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 PVD30359.1 - 3.5 6.9 73.5 0.64 9.3 19.8 3.8 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 PVD30359.1 - 6.4 6.8 21.1 0.56 10.3 3.4 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRKG1_interact PF15898.5 PVD30359.1 - 6.4 7.7 64.8 0.048 14.6 11.2 5.4 1 1 4 5 5 5 0 cGMP-dependent protein kinase interacting domain SPA PF08616.10 PVD30361.1 - 1.5e-11 44.2 0.1 3.1e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 PVD30361.1 - 6.9e-10 39.0 0.2 5.4e-09 36.0 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 PVD30361.1 - 8.5e-08 31.3 0.1 3.5e-05 22.7 0.1 2.1 1 1 1 2 2 2 2 Transport protein Avl9 Imm68 PF15583.6 PVD30361.1 - 0.03 14.5 0.1 0.051 13.8 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 68 Bromodomain PF00439.25 PVD30362.1 - 1.6e-13 50.5 0.4 4.5e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 Bromodomain Rhodanese PF00581.20 PVD30363.1 - 1.4e-09 38.4 0.0 3.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain DUF1378 PF07125.11 PVD30363.1 - 0.078 13.2 0.5 0.2 11.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) MOZ_SAS PF01853.18 PVD30364.1 - 1.5e-75 252.8 1.5 2.6e-75 252.0 1.5 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PVD30364.1 - 9.7e-15 53.9 1.2 9.7e-15 53.9 1.2 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2HC PF01530.18 PVD30364.1 - 2.1e-12 47.0 7.0 6.8e-12 45.4 7.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 PVD30364.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metal_resist PF13801.6 PVD30364.1 - 0.6 10.3 3.9 1 9.5 3.9 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Aldo_ket_red PF00248.21 PVD30365.1 - 2.5e-34 118.8 0.0 3.9e-24 85.4 0.0 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family Sulfotransfer_1 PF00685.27 PVD30365.1 - 1.3e-17 64.2 0.0 7.6e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD30365.1 - 2.4e-09 37.9 0.1 9.2e-08 32.7 0.1 2.6 1 1 0 1 1 1 1 Sulfotransferase family DUF3627 PF12299.8 PVD30365.1 - 0.072 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) cNMP_binding PF00027.29 PVD30366.1 - 1.7e-22 79.3 1.2 3.5e-13 49.4 0.1 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain HCV_capsid PF01543.17 PVD30366.1 - 0.11 12.7 2.8 0.3 11.3 2.8 1.7 1 0 0 1 1 1 0 Hepatitis C virus capsid protein zf-RING_11 PF17123.5 PVD30367.1 - 4.6e-06 26.3 4.0 0.00033 20.3 0.1 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_2 PF13639.6 PVD30367.1 - 9.6e-06 25.8 5.7 0.004 17.4 0.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 PVD30367.1 - 0.0028 17.4 4.7 0.11 12.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD30367.1 - 0.21 11.7 4.7 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD30367.1 - 0.29 11.1 6.0 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30367.1 - 0.82 9.7 8.9 8.2 6.5 0.4 2.6 2 1 0 2 2 2 0 zinc-RING finger domain DAN PF03045.15 PVD30368.1 - 4e-05 23.6 4.8 4e-05 23.6 4.8 1.6 2 0 0 2 2 2 1 DAN domain UPF0047 PF01894.17 PVD30369.1 - 1.4e-34 118.7 0.0 1.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Peptidase_C2 PF00648.21 PVD30370.1 - 3.1e-84 282.5 0.1 4.4e-84 282.0 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease WD40 PF00400.32 PVD30371.1 - 2.5e-07 31.3 2.1 9.1e-05 23.2 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD30371.1 - 0.00011 22.4 0.0 0.62 10.4 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD30371.1 - 0.011 15.6 0.0 0.62 9.9 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PVD30371.1 - 0.1 12.6 0.0 13 5.8 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BTB_2 PF02214.22 PVD30373.1 - 8.8e-19 67.7 0.1 3e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ubiquitin_3 PF14836.6 PVD30373.1 - 4.8e-07 29.7 0.0 1.5e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 PVD30373.1 - 2.5e-05 24.8 0.3 0.0019 18.7 0.2 2.7 2 1 0 2 2 2 1 DUSP domain BTB_3 PF16017.5 PVD30373.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Exonuc_VII_L PF02601.15 PVD30373.1 - 0.068 12.7 5.0 0.11 12.1 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF713 PF05218.14 PVD30373.1 - 0.13 12.0 7.1 0.22 11.3 5.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF713) UPF0242 PF06785.11 PVD30373.1 - 0.21 11.7 11.6 0.42 10.7 11.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Asp-B-Hydro_N PF05279.11 PVD30373.1 - 2.3 8.3 10.1 3.4 7.7 10.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FapA PF03961.13 PVD30373.1 - 3.9 6.0 6.6 5.5 5.5 6.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vps51 PF08700.11 PVD30375.1 - 6.3e-25 87.1 4.1 6.3e-25 87.1 4.1 2.7 4 0 0 4 4 3 1 Vps51/Vps67 Sec5 PF15469.6 PVD30375.1 - 1.9e-22 80.0 7.3 3e-22 79.4 5.7 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 PVD30375.1 - 3.3e-14 52.3 10.2 6.6e-14 51.4 10.2 1.5 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 PVD30375.1 - 1e-07 31.6 11.9 1e-07 31.6 11.9 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 PVD30375.1 - 4.6e-05 23.5 2.2 4.6e-05 23.5 2.2 3.6 3 1 1 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 PVD30375.1 - 0.0032 16.5 10.7 0.0063 15.5 10.7 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.9 PVD30375.1 - 0.0062 16.7 3.7 0.0062 16.7 3.7 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 PVD30375.1 - 0.042 13.7 6.4 0.051 13.5 1.8 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.13 PVD30375.1 - 0.047 14.4 0.5 0.047 14.4 0.5 3.2 1 1 3 4 4 4 0 Occludin homology domain MutS_III PF05192.18 PVD30375.1 - 0.11 12.8 6.0 0.22 11.7 4.9 1.9 1 1 1 2 2 2 0 MutS domain III zf-C4H2 PF10146.9 PVD30375.1 - 0.12 12.6 14.4 0.21 11.9 2.4 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein YxiJ PF14176.6 PVD30375.1 - 0.28 11.7 3.7 0.14 12.7 0.8 2.1 2 0 0 2 2 1 0 YxiJ-like protein DASH_Dam1 PF08653.10 PVD30375.1 - 0.32 10.8 4.0 0.26 11.1 0.3 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 MCPsignal PF00015.21 PVD30375.1 - 0.39 10.5 3.6 0.37 10.6 0.9 2.2 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0449 PF15136.6 PVD30375.1 - 1.1 9.8 6.9 1.1 9.8 0.6 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Med10 PF09748.9 PVD30375.1 - 1.9 8.5 5.9 1.7 8.6 0.4 3.4 3 2 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex GIT_CC PF16559.5 PVD30375.1 - 2.9 7.8 7.4 0.37 10.7 1.1 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Laminin_II PF06009.12 PVD30375.1 - 3.8 7.5 7.0 1.9 8.5 1.6 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF2115 PF09888.9 PVD30375.1 - 9.6 6.7 11.4 0.99 9.9 3.9 2.9 2 1 2 4 4 3 0 Uncharacterized protein conserved in archaea (DUF2115) Dynactin PF12455.8 PVD30376.1 - 1.2e-75 254.4 13.6 1.2e-75 254.4 13.6 4.4 3 2 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 PVD30376.1 - 6.7e-23 80.5 1.7 1.1e-22 79.7 1.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain RGP PF03214.13 PVD30376.1 - 0.09 11.9 1.5 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Reversibly glycosylated polypeptide ATG16 PF08614.11 PVD30376.1 - 8 6.6 111.6 0.63 10.2 12.4 7.4 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) Thermopsin PF05317.11 PVD30377.1 - 0.053 13.0 0.4 0.077 12.5 0.4 1.1 1 0 0 1 1 1 0 Thermopsin RRN3 PF05327.11 PVD30377.1 - 0.22 10.0 20.2 3.1e+02 -0.4 20.2 2.0 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-LYAR PF08790.11 PVD30377.1 - 0.22 11.4 2.7 0.6 10.1 2.7 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Vinculin PF01044.19 PVD30378.1 - 2.3e-284 946.3 34.2 1.6e-192 642.3 21.0 2.1 1 1 1 2 2 2 2 Vinculin family I_LWEQ PF01608.17 PVD30378.1 - 0.0076 16.5 4.2 0.0076 16.5 4.2 6.2 5 1 1 6 6 6 3 I/LWEQ domain D123 PF07065.14 PVD30378.1 - 0.012 14.7 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 D123 OmpH PF03938.14 PVD30378.1 - 0.042 14.2 15.8 1.7 9.0 0.0 5.3 5 0 0 5 5 5 0 Outer membrane protein (OmpH-like) T4_neck-protein PF11649.8 PVD30378.1 - 0.41 9.9 2.5 5.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Virus neck protein DivIC PF04977.15 PVD30378.1 - 1.5 8.7 5.4 0.44 10.4 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF1876 PF08962.11 PVD30378.1 - 1.9 8.5 7.6 0.76 9.8 0.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1876) DUF948 PF06103.11 PVD30378.1 - 2.2 8.6 8.7 27 5.1 0.1 4.8 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) THOC7 PF05615.13 PVD30378.1 - 8 6.8 9.8 2.8 8.2 0.3 3.9 4 0 0 4 4 4 0 Tho complex subunit 7 NAGidase PF07555.13 PVD30379.1 - 1.8e-68 231.1 0.0 2.7e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase NAGidase PF07555.13 PVD30380.1 - 1.1e-79 267.8 0.0 1.6e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Clathrin-link PF09268.10 PVD30380.1 - 2.6 7.5 4.2 0.68 9.4 0.3 2.1 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Pkinase_Tyr PF07714.17 PVD30381.1 - 4.5e-51 173.6 0.0 7.8e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD30381.1 - 2e-22 79.9 0.0 3.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Laminin_EGF PF00053.24 PVD30381.1 - 0.0031 17.6 2.1 0.0031 17.6 2.1 3.2 3 0 0 3 3 3 1 Laminin EGF domain Protocadherin PF08374.11 PVD30381.1 - 0.029 14.3 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 PVD30381.1 - 0.15 13.0 0.1 0.42 11.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Aminotran_1_2 PF00155.21 PVD30382.1 - 3.6e-77 260.0 0.0 3e-57 194.4 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Paz_1 PF18349.1 PVD30382.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 PAZ domain MFS_1 PF07690.16 PVD30383.1 - 5.3e-10 38.8 22.7 1.3e-09 37.5 12.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD30383.1 - 0.0015 17.9 4.7 0.0015 17.9 4.7 1.6 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB FtsX PF02687.21 PVD30383.1 - 0.63 10.5 8.4 4.7 7.7 8.4 2.4 1 1 0 1 1 1 0 FtsX-like permease family EVC2_like PF12297.8 PVD30384.1 - 2.1e-49 168.4 37.5 2.1e-49 168.4 37.5 3.9 3 1 0 3 3 3 1 Ellis van Creveld protein 2 like protein Methyltransf_12 PF08242.12 PVD30384.1 - 3.4 8.5 5.4 34 5.3 0.1 4.2 3 0 0 3 3 3 0 Methyltransferase domain Glycos_trans_3N PF02885.17 PVD30385.1 - 0.17 11.8 6.0 7.9 6.4 0.1 4.0 4 0 0 4 4 4 0 Glycosyl transferase family, helical bundle domain Mito_fiss_reg PF05308.11 PVD30388.1 - 0.21 11.6 6.6 0.23 11.5 6.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C4 PF00105.18 PVD30396.1 - 2.8e-11 43.7 0.9 4.3e-11 43.1 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RPA_interact_C PF14768.6 PVD30396.1 - 0.015 15.9 0.3 0.02 15.5 0.3 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal zf-CHY PF05495.12 PVD30396.1 - 0.037 14.5 1.1 0.049 14.1 1.1 1.2 1 0 0 1 1 1 0 CHY zinc finger C1_1 PF00130.22 PVD30396.1 - 0.044 13.7 2.8 0.074 13.0 2.8 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 PVD30396.1 - 0.048 13.7 1.9 0.08 13.0 1.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 PVD30396.1 - 0.1 12.8 0.5 0.1 12.8 0.5 1.8 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_2 PF03107.16 PVD30396.1 - 0.17 12.2 3.2 0.27 11.6 3.2 1.3 1 0 0 1 1 1 0 C1 domain Hormone_recep PF00104.30 PVD30397.1 - 4e-15 55.9 0.1 7.5e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD30397.1 - 3.2e-07 30.7 7.5 5.3e-07 30.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF777 PF05606.11 PVD30397.1 - 0.031 14.0 0.6 0.91 9.3 0.3 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) SelK_SelG PF10961.8 PVD30397.1 - 1.5 9.5 6.0 3 8.5 6.0 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Integrase_H2C2 PF17921.1 PVD30403.1 - 5e-20 71.4 0.4 9e-20 70.5 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5320 PF17253.2 PVD30408.1 - 6.1 8.0 16.6 14 6.8 14.7 2.0 1 1 0 2 2 2 0 Family of unknown function (DUF5320) HLH PF00010.26 PVD30410.1 - 2.4e-11 43.4 0.3 8.3e-11 41.7 0.3 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KASH_CCD PF14662.6 PVD30410.1 - 0.0024 17.7 2.9 0.004 17.0 2.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH YscO-like PF16789.5 PVD30410.1 - 0.022 14.8 3.4 0.04 13.9 3.4 1.4 1 0 0 1 1 1 0 YscO-like protein G-gamma PF00631.22 PVD30410.1 - 0.066 13.2 0.3 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 GGL domain Gal-3-0_sulfotr PF06990.11 PVD30411.1 - 9.7e-20 70.8 0.2 6.6e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 PVD30412.1 - 4.4e-11 42.3 0.1 5.5e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD30412.1 - 0.064 13.1 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase family Pkinase PF00069.25 PVD30413.1 - 3.3e-68 229.9 0.0 3.8e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30413.1 - 3.1e-35 121.7 0.0 3.6e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD30413.1 - 4.2e-05 22.7 0.0 0.00044 19.3 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD30413.1 - 0.0014 18.0 0.0 0.049 12.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 PVD30413.1 - 0.0034 16.5 0.1 0.005 15.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PVD30413.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 PVD30413.1 - 0.061 12.9 0.1 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWIB PF02201.18 PVD30414.1 - 1.1e-23 82.9 0.1 2.3e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Sar8_2 PF03058.14 PVD30416.1 - 0.099 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Sar8.2 family Peptidase_M10 PF00413.24 PVD30417.1 - 5.5e-24 84.8 0.4 9e-24 84.1 0.4 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 PVD30417.1 - 3.2e-08 33.4 16.2 0.0013 18.7 1.0 4.3 4 0 0 4 4 4 2 Hemopexin Reprolysin_5 PF13688.6 PVD30417.1 - 0.00024 21.3 0.1 0.00038 20.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 PVD30417.1 - 0.0034 16.1 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_4 PF13583.6 PVD30417.1 - 0.011 15.4 1.5 0.026 14.2 0.1 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 PVD30417.1 - 0.015 14.5 0.2 0.027 13.7 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 PVD30417.1 - 0.043 13.8 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Spectrin_like PF18373.1 PVD30417.1 - 0.075 13.1 0.0 0.97 9.5 0.0 2.5 2 0 0 2 2 2 0 Spectrin like domain Astacin PF01400.24 PVD30417.1 - 0.08 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 PVD30417.1 - 0.1 13.2 1.9 0.17 12.4 1.9 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD30418.1 - 1.6e-07 31.3 0.0 1.8e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 PVD30419.1 - 1.9e-06 28.0 0.1 1.5e-05 25.1 0.0 2.3 2 1 0 2 2 2 1 Putative peptidoglycan binding domain Dicty_REP PF05086.12 PVD30419.1 - 0.17 9.8 0.5 0.18 9.8 0.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IGF2_C PF08365.11 PVD30419.1 - 0.19 11.8 10.2 0.9 9.6 2.7 2.8 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide LRR_8 PF13855.6 PVD30422.1 - 2.9e-18 65.4 3.8 7.3e-15 54.5 1.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat 7tm_2 PF00002.24 PVD30422.1 - 9.2e-14 51.3 10.1 2.7e-13 49.8 10.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) LRR_4 PF12799.7 PVD30422.1 - 8.5e-11 41.9 8.1 1.3e-05 25.5 1.5 3.1 3 0 0 3 3 2 2 Leucine Rich repeats (2 copies) GPS PF01825.21 PVD30422.1 - 2.1e-10 41.0 0.0 5.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_5 PF13306.6 PVD30422.1 - 7.7e-08 32.4 0.0 7.7e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 PVD30422.1 - 9e-08 32.6 0.0 7.7e-07 29.6 0.0 2.7 2 0 0 2 2 1 1 Immunoglobulin domain I-set PF07679.16 PVD30422.1 - 1.2e-07 31.7 0.1 2.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD30422.1 - 2.9e-07 30.6 1.4 6.9e-07 29.4 0.1 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 PVD30422.1 - 0.00056 19.5 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 PVD30422.1 - 0.013 15.9 3.3 1.1 10.1 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat C2-set_2 PF08205.12 PVD30422.1 - 0.049 13.7 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 1 0 CD80-like C2-set immunoglobulin domain HRM PF02793.22 PVD30422.1 - 0.06 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Hormone receptor domain V-set PF07686.17 PVD30422.1 - 0.098 12.8 0.5 0.58 10.4 0.0 2.7 3 0 0 3 3 2 0 Immunoglobulin V-set domain WTF PF03303.13 PVD30422.1 - 4.7 6.9 10.7 47 3.6 0.0 3.5 2 1 1 3 3 3 0 WTF protein Ribosomal_L27e PF01777.18 PVD30424.1 - 2e-37 127.4 9.8 2.7e-37 127.0 9.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 PVD30424.1 - 0.0029 17.5 0.5 0.0054 16.6 0.5 1.5 1 0 0 1 1 1 1 KOW motif TRAM_LAG1_CLN8 PF03798.16 PVD30425.1 - 1.4e-42 145.7 27.1 1.7e-42 145.4 27.1 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 PVD30425.1 - 1.2e-09 37.9 0.2 2.2e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD30425.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PVD30425.1 - 0.061 13.2 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain Y_phosphatase PF00102.27 PVD30426.1 - 6.3e-63 212.5 6.4 8.3e-49 166.3 0.2 2.6 2 1 1 3 3 3 2 Protein-tyrosine phosphatase Receptor_IA-2 PF11548.8 PVD30426.1 - 3.8e-08 33.2 0.0 9.2e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 DUF4381 PF14316.6 PVD30426.1 - 0.021 15.1 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM51 PF15345.6 PVD30426.1 - 0.034 14.0 0.2 0.086 12.7 0.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 CD34_antigen PF06365.12 PVD30426.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family CcmD PF04995.14 PVD30426.1 - 0.065 13.3 1.5 0.18 11.9 1.5 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Miga PF10265.9 PVD30426.1 - 0.087 11.8 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 Mitoguardin Neur_chan_memb PF02932.16 PVD30426.1 - 0.35 10.9 0.9 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Podoplanin PF05808.11 PVD30426.1 - 1.6 8.8 3.6 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Podoplanin TP2 PF01254.18 PVD30427.1 - 0.017 15.7 6.3 0.042 14.4 1.5 2.1 1 1 1 2 2 2 0 Nuclear transition protein 2 Na_Ca_ex PF01699.24 PVD30430.1 - 3.2e-50 170.0 51.1 2.3e-28 99.1 19.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2157 PF09925.9 PVD30430.1 - 8.4 6.2 21.0 0.37 10.6 0.5 4.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Slu7 PF11708.8 PVD30431.1 - 1.5e-98 329.8 10.7 1.5e-98 329.8 10.7 2.7 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 PVD30431.1 - 0.016 15.3 4.0 0.033 14.3 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 PVD30431.1 - 0.02 14.7 1.2 0.046 13.6 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 PVD30431.1 - 0.032 14.0 1.0 0.089 12.5 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Vfa1 PF08432.10 PVD30431.1 - 3.3 8.0 30.1 0.41 10.9 13.9 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 UPF0054 PF02130.17 PVD30432.1 - 1.1e-30 106.1 0.1 1.3e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF2478 PF10649.9 PVD30432.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) SOCS_box PF07525.16 PVD30433.1 - 9.9e-09 35.4 0.2 3.3e-08 33.7 0.2 1.9 1 0 0 1 1 1 1 SOCS box Ank_3 PF13606.6 PVD30433.1 - 0.092 13.4 0.0 6.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Gal-3-0_sulfotr PF06990.11 PVD30434.1 - 2.3e-23 82.7 7.1 1.5e-18 66.9 3.5 2.1 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Glycos_transf_2 PF00535.26 PVD30435.1 - 4e-39 134.1 0.0 1e-38 132.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD30435.1 - 9.8e-29 100.2 2.7 1.5e-28 99.5 2.7 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PVD30435.1 - 2e-09 37.7 0.0 7.6e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD30435.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 PVD30435.1 - 0.00014 22.6 1.2 0.8 10.5 1.2 2.7 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 PVD30435.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Casc1_N PF15927.5 PVD30435.1 - 8.5 6.0 20.4 17 5.0 20.4 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus U79_P34 PF03064.16 PVD30435.1 - 9.1 5.6 11.4 22 4.3 11.4 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 7tm_2 PF00002.24 PVD30438.1 - 3e-72 242.8 12.7 3.7e-72 242.5 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30438.1 - 0.012 15.9 0.1 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 Hormone receptor domain Reeler PF02014.16 PVD30439.1 - 4.2e-19 69.6 0.8 4.2e-19 69.6 0.8 1.6 2 0 0 2 2 2 1 Reeler domain DOMON PF03351.17 PVD30439.1 - 2.4e-12 47.1 0.3 5.4e-12 46.0 0.3 1.6 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 PVD30439.1 - 1.1e-06 28.8 2.7 2e-06 28.0 2.0 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 PVD30439.1 - 0.0033 17.6 0.9 0.0087 16.2 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 PVD30439.1 - 0.0089 15.6 9.3 0.11 12.1 0.8 2.7 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 MucB_RseB PF03888.14 PVD30439.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Slu7 PF11708.8 PVD30440.1 - 5.3e-64 216.6 6.4 1.5e-62 211.8 0.3 3.7 4 1 1 5 5 5 2 Pre-mRNA splicing Prp18-interacting factor VIT1 PF01988.19 PVD30440.1 - 0.1 12.4 0.4 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 VIT family AP3D1 PF06375.11 PVD30440.1 - 0.71 10.1 21.9 0.15 12.3 15.8 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 HA2 PF04408.23 PVD30440.1 - 0.74 10.1 3.7 3.1 8.1 3.7 2.1 1 1 0 1 1 1 0 Helicase associated domain (HA2) CDC45 PF02724.14 PVD30440.1 - 1.8 6.8 10.7 3 6.0 10.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 PVD30440.1 - 5.9 7.2 19.6 0.027 14.8 8.3 2.5 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Reeler PF02014.16 PVD30441.1 - 3.7e-27 95.6 0.2 8.2e-27 94.5 0.1 1.6 2 0 0 2 2 2 1 Reeler domain DOMON PF03351.17 PVD30441.1 - 1.2e-11 44.9 0.1 2.8e-11 43.7 0.1 1.7 1 1 0 1 1 1 1 DOMON domain Reeler PF02014.16 PVD30442.1 - 3.7e-07 30.9 0.1 5.7e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Reeler domain p450 PF00067.22 PVD30443.1 - 8.9e-28 97.2 0.2 2e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 UDG PF03167.19 PVD30444.1 - 1.9e-22 79.9 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily zf-RING_UBOX PF13445.6 PVD30446.1 - 2.1e-09 37.2 2.6 5.4e-09 35.9 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD30446.1 - 6.7e-07 29.4 1.0 6.7e-07 29.4 1.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD30446.1 - 1.5e-06 28.0 2.2 3.3e-06 26.9 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD30446.1 - 1.5e-06 27.9 2.5 3.3e-06 26.8 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD30446.1 - 3.3e-06 26.9 1.2 3.3e-06 26.9 1.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30446.1 - 7.2e-06 25.9 4.8 1.9e-05 24.5 4.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD30446.1 - 2.1e-05 24.3 1.7 4.6e-05 23.2 1.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD30446.1 - 0.0009 19.5 6.6 0.0025 18.1 6.6 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 PVD30446.1 - 0.025 14.4 0.9 0.057 13.3 0.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 PVD30446.1 - 0.095 12.5 0.7 0.095 12.5 0.7 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 PVD30446.1 - 0.16 12.1 1.7 0.43 10.7 1.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 PVD30446.1 - 1.2 9.3 5.6 2.5 8.3 5.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 PVD30446.1 - 2.6 8.2 6.1 8.9 6.4 6.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 PVD30446.1 - 3.4 8.0 8.4 40 4.5 4.9 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD30446.1 - 6.4 6.7 7.0 7.5 6.4 4.6 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-H2C2_5 PF13909.6 PVD30447.1 - 8.5e-10 38.2 24.2 7.9e-06 25.5 4.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD30447.1 - 1.4e-05 25.3 12.9 0.021 15.2 2.1 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD30447.1 - 0.0066 16.8 28.0 0.026 15.0 2.2 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 PVD30447.1 - 0.042 13.5 7.0 0.37 10.4 3.0 2.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PUB PF09409.10 PVD30447.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 PUB domain zf-C2H2_7 PF15269.6 PVD30447.1 - 0.44 10.7 3.6 2.9 8.1 0.6 2.5 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_4 PF13894.6 PVD30447.1 - 1.8 9.6 20.1 1.1 10.3 4.0 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 PVD30447.1 - 6 7.4 7.0 0.39 11.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OrsD PF12013.8 PVD30447.1 - 8.7 6.8 12.7 36 4.8 10.6 3.1 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D CH_2 PF06294.11 PVD30448.1 - 6.5e-30 103.1 0.1 1.2e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PVD30448.1 - 2.5e-13 49.7 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 PVD30448.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain PKcGMP_CC PF16808.5 PVD30448.1 - 0.0075 16.1 1.9 0.018 14.9 0.5 2.5 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Adaptin_binding PF10199.9 PVD30448.1 - 0.076 13.6 1.2 6.2 7.4 0.1 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SlyX PF04102.12 PVD30448.1 - 0.078 13.6 4.9 1.9 9.2 0.1 2.5 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 PVD30448.1 - 0.088 12.8 2.7 2.1 8.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 PVD30448.1 - 0.3 11.2 7.9 4.2 7.5 0.4 2.4 2 0 0 2 2 2 0 Tropomyosin like CH_2 PF06294.11 PVD30449.1 - 4.1e-19 68.5 0.1 8.2e-19 67.5 0.0 1.5 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PVD30449.1 - 0.00053 19.8 0.3 0.00086 19.1 0.0 1.5 2 0 0 2 2 2 1 CAMSAP CH domain PKcGMP_CC PF16808.5 PVD30449.1 - 0.0043 16.9 0.8 0.0043 16.9 0.8 2.9 2 1 1 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SPATA24 PF15175.6 PVD30449.1 - 0.048 13.5 3.7 0.091 12.7 1.8 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 PBP PF01161.20 PVD30450.1 - 3.8e-10 40.2 0.0 4.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein OTU PF02338.19 PVD30451.1 - 1.9e-31 109.2 0.0 3.7e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease AnkUBD PF18418.1 PVD30451.1 - 2.7e-27 94.7 0.0 5.3e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain zf-RanBP PF00641.18 PVD30451.1 - 0.0031 16.8 43.0 0.015 14.6 7.4 4.1 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others MGAT2 PF05060.14 PVD30452.1 - 8.2e-92 307.9 7.5 6.5e-77 258.9 2.0 2.1 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Methyltransf_22 PF13383.6 PVD30453.1 - 2.9e-17 63.1 0.9 3.8e-17 62.7 0.9 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD30453.1 - 4.4e-06 26.8 0.0 6.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain FAM178 PF14816.6 PVD30455.1 - 4.9e-49 167.3 7.2 1.1e-48 166.1 7.2 1.5 1 0 0 1 1 1 1 Family of unknown function, FAM178 PDZ PF00595.24 PVD30455.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Dynactin_p22 PF07426.11 PVD30455.1 - 0.052 13.4 2.4 0.58 10.0 0.2 2.9 2 0 0 2 2 2 0 Dynactin subunit p22 DUF3213 PF11491.8 PVD30455.1 - 0.1 12.8 0.3 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) UPF0731 PF14982.6 PVD30456.1 - 0.13 12.4 1.1 0.54 10.5 0.1 2.2 2 0 0 2 2 2 0 UPF0731 family PDZ PF00595.24 PVD30457.1 - 0.093 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Toxin_TOLIP PF00087.21 PVD30458.1 - 0.015 15.5 0.7 0.023 15.0 0.7 1.3 1 0 0 1 1 1 0 Snake toxin and toxin-like protein LANC_like PF05147.13 PVD30460.1 - 6e-87 291.5 0.2 6.9e-87 291.3 0.2 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 PVD30460.1 - 0.0031 16.6 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 TPR_8 PF13181.6 PVD30460.1 - 0.13 12.5 4.9 18 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat C5-epim_C PF06662.13 PVD30460.1 - 3.9 6.9 9.3 2.3 7.7 0.4 3.0 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus LANC_like PF05147.13 PVD30461.1 - 2.7e-84 282.7 0.0 3.4e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 PVD30461.1 - 0.028 13.5 0.3 0.12 11.4 0.2 1.9 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 PVD30461.1 - 0.055 13.0 0.2 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Cpn60_TCP1 PF00118.24 PVD30462.1 - 6.1e-70 236.2 14.3 3.5e-66 223.8 11.6 2.7 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family 4HB_MCP_1 PF12729.7 PVD30462.1 - 0.097 12.2 2.2 0.73 9.3 0.3 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Cpn10 PF00166.21 PVD30463.1 - 6.4e-19 67.8 0.6 1.3e-18 66.8 0.6 1.6 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Mago-bind PF09282.10 PVD30463.1 - 2e-15 56.4 0.9 3.6e-15 55.5 0.9 1.5 1 0 0 1 1 1 1 Mago binding rRNA_proc-arch PF13234.6 PVD30463.1 - 0.013 15.4 9.7 0.019 14.9 9.7 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain DUF573 PF04504.14 PVD30463.1 - 0.11 13.2 5.7 0.26 11.9 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF573 Rotamase_2 PF13145.6 PVD30463.1 - 0.13 13.1 6.9 0.066 14.0 3.8 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Neur_chan_memb PF02932.16 PVD30463.1 - 0.18 11.9 1.3 0.19 11.8 1.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpecificRecomb PF10136.9 PVD30463.1 - 0.3 9.4 0.2 0.36 9.1 0.2 1.0 1 0 0 1 1 1 0 Site-specific recombinase AAA_23 PF13476.6 PVD30463.1 - 0.31 11.5 12.9 0.45 11.0 12.9 1.3 1 0 0 1 1 1 0 AAA domain Baculo_F PF12259.8 PVD30463.1 - 0.57 8.6 6.9 0.66 8.4 6.9 1.0 1 0 0 1 1 1 0 Baculovirus F protein Integrin_alpha2 PF08441.12 PVD30464.1 - 8.3e-86 288.7 0.3 1e-85 288.4 0.3 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 PVD30464.1 - 1.2e-24 86.1 19.5 4.6e-10 39.4 6.6 3.9 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 PVD30464.1 - 7.7e-12 45.6 3.1 8.9e-06 26.2 0.6 3.8 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 PVD30464.1 - 0.0059 16.5 1.3 0.0059 16.5 1.3 2.0 2 0 0 2 2 2 1 Integrin alpha cytoplasmic region Protocadherin PF08374.11 PVD30464.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Protocadherin Collectrin PF16959.5 PVD30464.1 - 0.087 12.6 0.3 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Renal amino acid transporter HisK_sensor PF18698.1 PVD30464.1 - 0.13 12.7 1.9 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Histidine kinase sensor domain DUF842 PF05811.13 PVD30465.1 - 3.8e-24 84.9 10.4 4.6e-24 84.6 10.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ACDC PF14733.6 PVD30465.1 - 0.0027 18.0 1.0 0.0037 17.6 1.0 1.1 1 0 0 1 1 1 1 AP2-coincident C-terminal zf-Tim10_DDP PF02953.15 PVD30465.1 - 0.013 15.2 9.8 0.24 11.1 9.8 2.1 1 1 0 1 1 1 0 Tim10/DDP family zinc finger YlqD PF11068.8 PVD30465.1 - 0.059 13.7 0.1 0.065 13.6 0.1 1.1 1 0 0 1 1 1 0 YlqD protein Vanabin-2 PF11437.8 PVD30465.1 - 0.074 13.2 10.5 0.14 12.3 10.6 1.5 1 1 0 1 1 1 0 Vanadium-binding protein 2 WD40 PF00400.32 PVD30466.1 - 3.4e-07 30.8 6.4 0.37 11.7 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4506 PF14958.6 PVD30467.1 - 2.8e-24 85.2 0.1 7.2e-24 83.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) SARS_lipid_bind PF09399.10 PVD30467.1 - 0.04 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 SARS lipid binding protein Ifi-6-16 PF06140.13 PVD30467.1 - 0.14 12.1 2.0 0.26 11.2 1.2 1.8 2 0 0 2 2 2 0 Interferon-induced 6-16 family BAMBI PF06211.12 PVD30468.1 - 1.8e-14 53.9 8.0 2.8e-12 46.8 2.7 2.3 1 1 1 2 2 2 2 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.23 PVD30468.1 - 0.00092 20.3 12.6 0.016 16.3 12.6 2.3 1 1 0 1 1 1 1 Activin types I and II receptor domain DUF1180 PF06679.12 PVD30468.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAP_N PF01213.19 PVD30470.1 - 0.019 14.5 5.2 0.019 14.5 5.2 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD30470.1 - 0.11 12.6 5.7 0.047 13.8 3.3 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD30470.1 - 4.1 7.4 12.8 0.51 10.4 6.2 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RCDG1 PF15725.5 PVD30470.1 - 7.5 7.1 10.9 73 3.9 0.0 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Pkinase_Tyr PF07714.17 PVD30476.1 - 1.4e-62 211.3 0.0 2.1e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD30476.1 - 2e-54 184.7 0.0 4.2e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 PVD30476.1 - 3.5e-13 49.5 0.1 1.2e-12 47.7 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD30476.1 - 3.3e-12 46.7 0.1 7.1e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD30476.1 - 0.021 14.8 0.7 0.042 13.8 0.1 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF3552 PF12072.8 PVD30476.1 - 0.036 13.5 5.8 0.059 12.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SAM_4 PF18017.1 PVD30476.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NHL PF01436.21 PVD30477.1 - 1.7e-47 157.1 18.8 6.6e-10 38.5 0.1 6.5 6 0 0 6 6 6 5 NHL repeat DUF5128 PF17170.4 PVD30477.1 - 8.8e-18 64.5 9.5 1.5e-07 30.9 0.7 3.7 3 1 0 3 3 3 3 6-bladed beta-propeller SGL PF08450.12 PVD30477.1 - 4.3e-13 49.4 0.9 0.0006 19.5 0.1 3.3 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 PVD30477.1 - 3.1e-07 30.3 7.4 3.1e-07 30.3 7.4 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD30477.1 - 3.1e-07 30.1 6.7 3.1e-07 30.1 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Lactonase PF10282.9 PVD30477.1 - 1.8e-06 27.5 0.4 0.00067 19.0 0.1 2.5 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller zf-C3HC4_3 PF13920.6 PVD30477.1 - 4.3e-05 23.3 19.9 0.00011 22.0 7.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD30477.1 - 4.9e-05 23.1 8.8 4.9e-05 23.1 8.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30477.1 - 9.2e-05 22.3 6.5 9.2e-05 22.3 6.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD30477.1 - 0.00012 22.1 8.2 0.00012 22.1 8.2 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Phytase-like PF13449.6 PVD30477.1 - 0.00016 21.7 0.6 0.69 9.8 0.0 4.1 4 1 0 4 4 4 1 Esterase-like activity of phytase zf-RING_2 PF13639.6 PVD30477.1 - 0.00026 21.3 8.4 0.00026 21.3 8.4 2.4 2 0 0 2 2 2 1 Ring finger domain TolB_like PF15869.5 PVD30477.1 - 0.0004 19.7 0.0 0.013 14.8 0.0 2.1 1 1 1 2 2 2 2 TolB-like 6-blade propeller-like SBBP PF06739.11 PVD30477.1 - 0.00056 19.8 0.0 7.5 6.6 0.0 4.0 3 0 0 3 3 3 1 Beta-propeller repeat Arylesterase PF01731.20 PVD30477.1 - 0.0081 16.3 0.0 4.6 7.5 0.0 3.7 4 0 0 4 4 4 1 Arylesterase zf-RING_11 PF17123.5 PVD30477.1 - 0.018 14.8 2.1 0.018 14.8 2.1 2.4 2 0 0 2 2 1 0 RING-like zinc finger Apolipoprotein PF01442.18 PVD30477.1 - 0.023 14.6 2.5 0.036 13.9 2.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 PVD30477.1 - 0.088 12.8 0.7 0.18 11.8 0.7 1.4 1 0 0 1 1 1 0 Laminin Domain II DASH_Spc19 PF08287.11 PVD30477.1 - 5 7.0 10.0 0.28 11.1 4.4 1.7 2 0 0 2 2 2 0 Spc19 Kelch_1 PF01344.25 PVD30478.1 - 2.7e-46 154.9 0.0 2e-13 49.7 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PVD30478.1 - 7.7e-28 95.8 0.3 1.6e-08 34.6 0.0 5.6 2 2 3 5 5 5 4 Kelch motif Kelch_2 PF07646.15 PVD30478.1 - 8.5e-18 63.6 0.0 2.1e-05 24.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 PVD30478.1 - 5.1e-15 55.2 0.3 0.0017 18.3 0.0 4.9 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PVD30478.1 - 2.9e-12 46.5 0.0 0.14 12.5 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.15 PVD30478.1 - 5.9e-10 39.2 0.2 9.5e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 PVD30478.1 - 5.3e-09 35.9 0.0 0.78 9.8 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Varsurf_PPLC PF03490.13 PVD30478.1 - 0.014 15.3 0.3 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 Variant-surface-glycoprotein phospholipase C DUF1668 PF07893.13 PVD30478.1 - 0.016 14.6 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) Avl9 PF09794.9 PVD30479.1 - 1.4e-122 409.1 0.0 9.8e-122 406.3 0.0 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 PVD30479.1 - 4.7e-09 36.2 0.0 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 PVD30479.1 - 1.1e-08 35.0 0.6 2.8e-06 27.1 0.2 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 PVD30479.1 - 0.0003 20.8 1.6 0.052 13.5 0.5 3.1 3 1 0 3 3 3 1 DENN (AEX-3) domain Afi1 PF07792.12 PVD30479.1 - 0.0081 16.6 0.0 0.0081 16.6 0.0 3.2 4 0 0 4 4 4 1 Docking domain of Afi1 for Arf3 in vesicle trafficking PARP PF00644.20 PVD30480.1 - 1.5e-19 70.4 0.5 1.7e-18 67.0 0.5 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UBA_4 PF14555.6 PVD30480.1 - 3.2e-05 23.6 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain ART-PolyVal PF18760.1 PVD30480.1 - 0.036 15.1 1.1 0.12 13.4 0.0 2.4 3 0 0 3 3 3 0 ADP-Ribosyltransferase in polyvalent proteins TPR_19 PF14559.6 PVD30481.1 - 8e-17 61.5 0.4 8.2e-06 26.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD30481.1 - 7.3e-14 51.1 0.1 0.00033 20.8 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD30481.1 - 1e-13 50.3 6.5 0.0044 17.0 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD30481.1 - 3.2e-12 45.7 7.1 0.013 15.3 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD30481.1 - 3.7e-12 45.4 10.1 0.041 14.1 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD30481.1 - 1e-10 41.5 3.6 0.4 11.6 0.0 5.4 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD30481.1 - 5.4e-09 35.6 1.2 1.3 8.8 0.1 5.2 3 1 2 5 5 5 4 TPR repeat TPR_9 PF13371.6 PVD30481.1 - 1e-08 35.1 0.0 5.6e-06 26.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD30481.1 - 9.4e-07 29.4 0.0 0.084 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD30481.1 - 2.6e-05 24.4 2.4 0.035 14.4 0.0 5.1 4 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD30481.1 - 4.1e-05 23.7 0.3 0.17 12.1 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PVD30481.1 - 8.4e-05 22.6 1.6 0.13 12.3 0.1 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PVD30481.1 - 0.00011 22.7 2.4 0.047 14.1 0.2 3.5 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_6 PF13174.6 PVD30481.1 - 0.0012 19.3 2.5 19 6.2 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD30481.1 - 0.0014 18.6 0.5 25 5.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 PVD30481.1 - 0.0037 16.2 1.4 1.8 7.4 0.0 3.2 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 PVD30481.1 - 0.0094 15.2 0.2 11 5.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD30481.1 - 0.012 15.0 1.6 0.68 9.2 0.0 3.1 3 1 1 4 4 4 0 MalT-like TPR region ChAPs PF09295.10 PVD30481.1 - 0.035 13.1 0.1 4.8 6.1 0.0 2.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 PVD30481.1 - 0.047 12.9 0.4 3.2 6.9 0.0 2.7 2 1 1 3 3 3 0 FAT domain Coatomer_E PF04733.14 PVD30481.1 - 0.089 12.2 0.2 3.8 6.8 0.0 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit Pkinase PF00069.25 PVD30482.1 - 1.8e-39 135.7 0.0 2.4e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30482.1 - 1.4e-21 77.0 0.0 3.5e-14 52.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD30482.1 - 2.7e-05 23.6 0.0 0.00023 20.6 0.0 2.1 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 PVD30482.1 - 0.0038 17.2 0.0 0.017 15.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Dynamitin PF04912.14 PVD30483.1 - 1.7e-113 379.9 22.2 1.9e-113 379.7 22.2 1.0 1 0 0 1 1 1 1 Dynamitin DUF948 PF06103.11 PVD30483.1 - 0.0088 16.3 14.4 1.1 9.6 1.0 4.2 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) Peptidase_C11 PF03415.14 PVD30483.1 - 0.017 14.6 1.1 0.029 13.8 1.1 1.6 1 0 0 1 1 1 0 Clostripain family DUF4649 PF15507.6 PVD30483.1 - 0.022 14.7 0.1 0.062 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) FlaC_arch PF05377.11 PVD30483.1 - 0.025 15.0 13.5 2.6 8.5 0.2 5.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 PVD30483.1 - 0.026 14.6 13.1 0.99 9.4 0.3 3.5 4 0 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugarporin_N PF11471.8 PVD30483.1 - 0.052 13.5 1.7 8.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CorA PF01544.18 PVD30483.1 - 0.061 12.6 14.0 2.6 7.3 0.2 3.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein HALZ PF02183.18 PVD30483.1 - 0.074 13.3 4.5 17 5.8 0.5 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper CDPS PF16715.5 PVD30483.1 - 0.078 12.6 3.4 0.13 11.9 0.3 2.4 2 1 0 2 2 2 0 Cyclodipeptide synthase Spectrin PF00435.21 PVD30483.1 - 0.12 12.9 19.0 0.38 11.3 0.4 4.2 2 1 3 5 5 5 0 Spectrin repeat Allexi_40kDa PF05549.11 PVD30483.1 - 0.15 11.5 13.5 3.9 6.9 2.8 3.4 2 1 1 3 3 3 0 Allexivirus 40kDa protein DUF1664 PF07889.12 PVD30483.1 - 0.19 11.8 15.1 1.2 9.1 1.9 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Kri1 PF05178.12 PVD30483.1 - 0.2 12.2 8.6 4.7 7.8 0.0 3.8 3 1 0 3 3 3 0 KRI1-like family Occludin_ELL PF07303.13 PVD30483.1 - 0.21 12.3 20.7 0.22 12.3 2.4 4.3 3 1 0 4 4 4 0 Occludin homology domain Methyltransf_32 PF13679.6 PVD30483.1 - 0.25 11.3 7.1 8.1 6.4 6.4 3.2 2 1 0 2 2 2 0 Methyltransferase domain DUF4795 PF16043.5 PVD30483.1 - 0.32 10.6 24.3 0.063 12.9 4.6 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) TFR_dimer PF04253.15 PVD30483.1 - 0.52 10.4 7.4 4.5 7.4 0.3 3.6 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain PMC2NT PF08066.12 PVD30483.1 - 0.57 10.9 5.8 2.4 8.9 2.0 3.5 3 1 1 4 4 3 0 PMC2NT (NUC016) domain HalX PF08663.10 PVD30483.1 - 0.61 10.5 9.4 1.4 9.3 0.3 4.4 3 1 2 5 5 4 0 HalX domain Fib_alpha PF08702.10 PVD30483.1 - 0.67 10.1 17.5 0.37 11.0 3.5 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family zf-ZPR1 PF03367.13 PVD30483.1 - 0.74 9.6 7.6 0.18 11.6 0.8 3.1 2 1 2 4 4 4 0 ZPR1 zinc-finger domain COG2 PF06148.11 PVD30483.1 - 1.2 9.3 14.6 11 6.2 0.6 3.7 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 PVD30483.1 - 1.2 9.7 20.8 0.086 13.3 1.3 4.4 2 1 0 2 2 1 0 Cell division protein ZapB DUF16 PF01519.16 PVD30483.1 - 1.2 9.7 17.4 3.2 8.3 0.1 3.9 2 1 0 2 2 1 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 PVD30483.1 - 1.4 9.0 20.5 2.2 8.4 0.7 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein SKA2 PF16740.5 PVD30483.1 - 1.9 8.3 25.7 0.1 12.4 1.6 4.5 4 1 0 4 4 4 0 Spindle and kinetochore-associated protein 2 H-kinase_dim PF02895.14 PVD30483.1 - 2.1 8.8 7.6 1.8 9.0 0.2 3.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Osmo_CC PF08946.10 PVD30483.1 - 2.2 8.6 7.0 0.33 11.3 0.3 3.1 4 0 0 4 4 3 0 Osmosensory transporter coiled coil FUSC PF04632.12 PVD30483.1 - 2.5 6.5 8.4 2.2 6.7 0.8 2.2 1 1 0 2 2 2 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 PVD30483.1 - 2.8 8.2 19.8 2.8 8.2 0.7 4.3 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain RecG_N PF17190.4 PVD30483.1 - 3 8.6 15.4 8.1 7.3 0.3 3.9 3 1 0 3 3 3 0 RecG N-terminal helical domain DUF2205 PF10224.9 PVD30483.1 - 4.3 7.4 11.8 0.16 12.0 0.6 3.8 2 1 1 4 4 4 0 Short coiled-coil protein DUF2408 PF10303.9 PVD30483.1 - 4.5 7.8 16.9 5.4 7.6 7.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) ZnuA PF01297.17 PVD30483.1 - 4.6 6.6 12.5 2 7.7 0.9 3.8 3 1 1 4 4 4 0 Zinc-uptake complex component A periplasmic DASH_Dad3 PF08656.10 PVD30483.1 - 5.1 7.3 13.2 0.47 10.6 0.2 4.1 3 1 0 3 3 3 0 DASH complex subunit Dad3 MFS_1 PF07690.16 PVD30484.1 - 2e-42 145.4 30.3 1e-41 143.0 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD30484.1 - 2.1e-08 33.5 8.5 2.1e-08 33.5 8.5 3.6 2 2 2 4 4 4 2 Sugar (and other) transporter DUF2826 PF11442.8 PVD30484.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2826) Citrate_synt PF00285.21 PVD30485.1 - 2.3e-107 359.2 0.0 3.9e-107 358.4 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Spindle_Spc25 PF08234.12 PVD30485.1 - 7.1e-06 26.1 0.1 1.8e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Occludin_ELL PF07303.13 PVD30485.1 - 5.5 7.8 7.3 0.83 10.4 1.6 2.4 1 1 1 2 2 2 0 Occludin homology domain CREPT PF16566.5 PVD30485.1 - 6.1 7.0 10.6 1.3 9.2 4.8 2.6 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Ras PF00071.22 PVD30486.1 - 1.6e-57 193.7 0.3 2e-57 193.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD30486.1 - 1.7e-37 128.3 0.1 2.6e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD30486.1 - 1.3e-18 67.0 0.2 1.6e-18 66.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD30486.1 - 3.9e-07 30.2 0.0 6.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD30486.1 - 5.2e-06 26.0 0.1 6.1e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD30486.1 - 8.4e-06 25.5 0.5 0.00011 21.8 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD30486.1 - 7.4e-05 22.7 0.1 0.0095 15.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 PVD30486.1 - 0.00024 20.9 0.1 0.00045 20.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 PVD30486.1 - 0.00077 18.9 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PVD30486.1 - 0.0019 18.6 0.1 0.0031 17.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PVD30486.1 - 0.0027 18.0 0.0 0.0081 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 PVD30486.1 - 0.0087 15.9 0.3 0.067 13.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF5035 PF16438.5 PVD30486.1 - 0.013 15.4 0.5 0.099 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5035) AAA_7 PF12775.7 PVD30486.1 - 0.013 15.0 0.2 0.031 13.8 0.0 1.7 2 1 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 PVD30486.1 - 0.014 15.9 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PVD30486.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 PVD30486.1 - 0.049 12.7 0.1 0.098 11.7 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain Septin PF00735.18 PVD30486.1 - 0.052 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin TniB PF05621.11 PVD30486.1 - 0.054 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein CENP-M PF11111.8 PVD30486.1 - 0.064 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ECSIT PF06239.11 PVD30487.1 - 3.2e-76 255.4 0.8 4.8e-76 254.8 0.8 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 PVD30487.1 - 9.2e-40 136.0 0.0 1.7e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein DUF2875 PF11394.8 PVD30487.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) Methyltransf_23 PF13489.6 PVD30488.1 - 2e-13 50.5 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD30488.1 - 4.3e-13 49.8 0.0 6.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD30488.1 - 1e-12 48.6 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD30488.1 - 1.5e-09 37.8 0.0 4.5e-09 36.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD30488.1 - 2.2e-09 37.8 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD30488.1 - 0.00014 21.3 0.0 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PVD30488.1 - 0.00092 18.8 0.0 0.0018 17.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.11 PVD30488.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 PVD30488.1 - 0.18 12.8 0.0 0.29 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rif1_N PF12231.8 PVD30491.1 - 1.3e-35 123.1 8.2 8.3e-25 87.6 1.0 3.7 2 1 1 3 3 3 3 Rap1-interacting factor 1 N terminal RAWUL PF16207.5 PVD30492.1 - 9e-15 55.1 0.2 1.4e-14 54.5 0.2 1.3 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Myc_N PF01056.18 PVD30492.1 - 0.016 15.1 8.9 0.022 14.6 8.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 PVD30492.1 - 1.2 8.7 8.1 1.6 8.3 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 PVD30492.1 - 4.1 6.0 8.2 5.1 5.6 8.2 1.1 1 0 0 1 1 1 0 Hamartin protein YjbH PF06082.11 PVD30497.1 - 0.21 10.3 2.5 0.36 9.6 2.5 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH RAWUL PF16207.5 PVD30499.1 - 2e-16 60.4 0.1 4.3e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 PVD30499.1 - 0.00093 19.0 3.1 0.0018 18.0 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD30499.1 - 0.004 17.5 1.2 0.0078 16.5 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD30499.1 - 0.027 14.3 2.5 0.049 13.5 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD30499.1 - 0.064 13.1 5.1 0.13 12.2 5.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD30499.1 - 0.14 12.5 1.8 0.28 11.5 1.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD30499.1 - 0.47 10.4 3.2 0.88 9.6 3.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RAWUL PF16207.5 PVD30501.1 - 3.9e-14 53.1 0.0 6.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like PIP5K PF01504.18 PVD30502.1 - 9.6e-78 261.2 0.1 1.9e-77 260.2 0.1 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ricin_B_lectin PF00652.22 PVD30503.1 - 2.5e-23 82.7 5.3 3.8e-23 82.1 5.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Tubulin PF00091.25 PVD30503.1 - 3.2e-19 69.9 0.0 6.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Glyco_transf_7C PF02709.14 PVD30503.1 - 5.8e-05 22.7 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 PVD30503.1 - 0.00017 21.5 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 RicinB_lectin_2 PF14200.6 PVD30503.1 - 0.0067 17.1 0.8 0.13 13.0 0.3 2.4 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like HLH PF00010.26 PVD30504.1 - 2.5e-14 53.0 3.9 2.5e-14 53.0 3.9 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2937 PF11157.8 PVD30504.1 - 0.42 10.3 1.7 0.6 9.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) WD40 PF00400.32 PVD30506.1 - 1.1e-15 57.7 7.4 2.8e-05 24.8 0.1 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 PVD30506.1 - 1.5e-05 24.5 17.3 1.5e-05 24.5 17.3 2.7 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 PVD30506.1 - 2.9e-05 24.3 2.2 1.4 9.3 0.1 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DZR PF12773.7 PVD30506.1 - 0.82 9.8 12.8 2.3 8.3 12.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_16 PF17034.5 PVD30506.1 - 6.8 6.9 21.3 1.3e+03 -0.5 21.3 3.2 1 1 0 1 1 1 0 Zinc-ribbon like family KOG2701 PF09762.9 PVD30507.1 - 3e-42 144.9 0.0 3e-42 144.9 0.0 4.1 2 1 1 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) SDH_beta PF03315.15 PVD30507.1 - 0.045 14.1 2.9 0.13 12.6 2.7 1.9 1 1 0 1 1 1 0 Serine dehydratase beta chain KH_5 PF13184.6 PVD30507.1 - 0.045 13.8 1.7 0.07 13.2 0.3 2.0 2 0 0 2 2 2 0 NusA-like KH domain SLATT_1 PF18181.1 PVD30507.1 - 0.41 10.6 6.2 11 5.9 0.9 3.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 YfhO PF09586.10 PVD30507.1 - 3.5 5.7 7.2 4.8 5.3 7.2 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CHGN PF05679.16 PVD30508.1 - 3.9e-140 468.1 1.6 4.6e-140 467.9 1.6 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase PH PF00169.29 PVD30509.1 - 9.1e-08 32.6 0.1 2.6e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 PVD30509.1 - 3.1e-05 24.0 0.4 7.8e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 SH2 domain DHDPS PF00701.22 PVD30510.1 - 7.3e-57 192.3 0.0 8.8e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_red PF03358.15 PVD30510.1 - 0.086 12.6 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 NADPH-dependent FMN reductase DHquinase_I PF01487.15 PVD30510.1 - 0.13 12.5 0.1 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Type I 3-dehydroquinase DHO_dh PF01180.21 PVD30510.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase C2 PF00168.30 PVD30511.1 - 1e-76 253.8 0.3 1.7e-13 50.7 0.0 8.5 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 PVD30511.1 - 2.6e-30 104.8 0.1 6.2e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 FerB (NUC096) domain FerA PF08165.11 PVD30511.1 - 1.9e-19 69.4 0.6 4.4e-19 68.2 0.6 1.7 1 0 0 1 1 1 1 FerA (NUC095) domain FerI PF08151.12 PVD30511.1 - 6.9e-19 67.7 0.4 1.9e-18 66.3 0.4 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain Pex24p PF06398.11 PVD30511.1 - 3.5e-09 36.1 21.9 1.3e-05 24.4 2.4 3.2 3 0 0 3 3 3 2 Integral peroxisomal membrane peroxin Ferlin_C PF16165.5 PVD30511.1 - 1.1e-07 31.9 5.5 6e-07 29.5 0.1 2.7 2 1 1 3 3 3 2 Ferlin C-terminus dsRBD2 PF17842.1 PVD30511.1 - 0.015 15.5 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DND1_DSRM PF14709.7 PVD30511.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Synaphin PF05835.12 PVD30512.1 - 1.2e-06 28.9 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Synaphin protein zf-C3HC4_3 PF13920.6 PVD30516.1 - 3.4e-07 30.0 7.6 3.4e-07 30.0 7.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD30516.1 - 0.00029 20.6 3.5 0.00029 20.6 3.5 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_14 PF17978.1 PVD30516.1 - 0.31 11.5 7.2 0.52 10.8 5.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RIIa PF02197.17 PVD30518.1 - 0.0059 16.3 0.7 0.0059 16.3 0.7 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit zf-H2C2_2 PF13465.6 PVD30520.1 - 4.2e-08 33.3 25.2 2.1e-05 24.8 0.9 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD30520.1 - 8.2e-08 32.3 26.1 0.0032 17.8 0.5 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD30520.1 - 0.0023 18.6 27.1 0.33 11.9 2.1 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD30520.1 - 0.0059 16.3 1.0 0.0059 16.3 1.0 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.7 PVD30520.1 - 0.014 15.8 0.9 0.014 15.8 0.9 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD30520.1 - 8.5 6.2 11.6 0.6 9.9 0.2 3.5 4 0 0 4 4 4 0 zinc-finger C2H2-type Methyltransf_25 PF13649.6 PVD30521.1 - 3.3e-07 30.9 0.0 7.2e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD30521.1 - 8.6e-05 23.1 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD30521.1 - 0.00031 21.4 0.0 0.00051 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD30521.1 - 0.0016 18.1 0.0 0.0045 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PVD30521.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PVD30521.1 - 0.0097 15.4 0.0 0.02 14.4 0.0 1.5 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 PVD30521.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.6 PVD30521.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 PVD30522.1 - 1.5e-06 28.8 0.0 3.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD30522.1 - 0.00032 21.3 0.0 0.00066 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD30522.1 - 0.0026 18.5 0.0 0.005 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD30522.1 - 0.0067 16.3 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PVD30522.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 PVD30522.1 - 0.04 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 PVD30522.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 PVD30522.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 PVD30523.1 - 9.2e-36 123.1 0.0 1.2e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30523.1 - 9.9e-26 90.7 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 PVD30523.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF2976 PF11190.8 PVD30523.1 - 0.058 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) LRR_4 PF12799.7 PVD30524.1 - 8.6e-14 51.4 13.3 0.11 13.0 0.0 8.9 9 2 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD30524.1 - 9.7e-10 37.7 18.0 0.77 10.0 0.0 11.2 13 2 1 14 14 14 3 Leucine Rich repeat LRR_1 PF00560.33 PVD30524.1 - 0.021 15.3 16.0 3.7 8.5 0.1 8.6 8 3 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD30524.1 - 0.049 13.4 7.2 0.54 10.1 0.1 5.7 6 2 0 6 6 6 0 Leucine rich repeat PKK PF12474.8 PVD30525.1 - 7.1e-56 188.2 92.8 1.3e-31 109.6 41.5 6.7 4 1 2 6 6 6 2 Polo kinase kinase Pkinase PF00069.25 PVD30525.1 - 9.9e-53 179.2 0.0 9.9e-53 179.2 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30525.1 - 5.5e-42 143.8 2.5 1.2e-41 142.7 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase DEAD PF00270.29 PVD30526.1 - 5.8e-46 156.5 0.5 1.8e-44 151.6 0.0 2.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD30526.1 - 1.1e-30 106.2 0.0 6e-30 103.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD30526.1 - 0.00067 19.7 0.2 0.0031 17.5 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 PVD30526.1 - 0.0029 17.6 1.8 0.0029 17.6 1.8 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 PVD30526.1 - 0.013 15.2 1.0 0.027 14.2 1.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger ERCC3_RAD25_C PF16203.5 PVD30526.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC_6 PF15288.6 PVD30526.1 - 0.16 11.8 0.2 0.47 10.3 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 PVD30526.1 - 0.59 9.9 3.3 0.29 10.9 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle IRS PF02174.17 PVD30527.1 - 3.7e-21 74.9 0.1 8.3e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 PVD30527.1 - 1.2e-07 32.2 1.6 4.8e-07 30.2 0.5 2.6 2 1 0 2 2 2 1 PH domain PH_6 PF15406.6 PVD30527.1 - 0.25 11.6 3.8 0.31 11.3 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain MCM_bind PF09739.9 PVD30527.1 - 0.28 9.6 8.2 7.5 4.9 10.4 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Sec62 PF03839.16 PVD30527.1 - 0.71 9.3 8.9 1.5 8.3 8.9 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 PVD30527.1 - 1.3 8.2 5.9 3.1 6.9 6.2 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter MADF_DNA_bdg PF10545.9 PVD30529.1 - 3.5e-19 68.9 6.9 6.4e-19 68.1 6.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 PVD30529.1 - 1.9e-05 24.6 4.0 5e-05 23.3 4.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PVD30529.1 - 0.0012 19.1 5.2 0.0012 19.1 5.2 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD30529.1 - 0.0039 17.4 1.7 0.0098 16.1 1.7 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.6 PVD30530.1 - 2.4e-13 49.7 11.2 3.5e-13 49.2 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD30530.1 - 1.6e-05 24.6 13.5 2.6e-05 24.0 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD30530.1 - 0.00012 22.3 12.2 0.00019 21.7 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PVD30530.1 - 0.00075 19.3 10.8 0.0013 18.6 10.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD30530.1 - 0.0022 17.8 13.0 0.0035 17.2 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1640 PF07798.11 PVD30530.1 - 0.012 15.7 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) ORF6C PF10552.9 PVD30530.1 - 0.032 14.3 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 ORF6C domain zf-RING_5 PF14634.6 PVD30530.1 - 0.048 13.6 12.9 0.074 13.0 12.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PseudoU_synth_1 PF01416.20 PVD30531.1 - 5.7e-09 36.4 0.0 1.4e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF1992 PF09350.10 PVD30531.1 - 0.008 16.3 0.9 0.045 13.9 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) AAA PF00004.29 PVD30532.1 - 4.7e-43 146.8 0.0 9.2e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD30532.1 - 1.8e-12 46.8 0.0 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PVD30532.1 - 5e-07 29.6 0.7 1.2e-06 28.3 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PVD30532.1 - 5.6e-07 29.8 0.0 1.3e-06 28.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PVD30532.1 - 2.3e-06 27.6 0.0 1e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD30532.1 - 3e-06 27.7 0.1 6e-05 23.5 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 PVD30532.1 - 9.3e-05 22.2 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD30532.1 - 0.0002 21.7 2.2 0.0069 16.7 0.3 2.7 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 PVD30532.1 - 0.0012 19.4 0.2 0.013 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 PVD30532.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PVD30532.1 - 0.002 17.4 0.0 0.0047 16.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PVD30532.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PVD30532.1 - 0.0065 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 PVD30532.1 - 0.007 15.8 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 PVD30532.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Filament PF00038.21 PVD30532.1 - 0.01 15.4 0.5 0.018 14.7 0.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein ATPase PF06745.13 PVD30532.1 - 0.012 14.9 0.2 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 KaiC RILP PF11461.8 PVD30532.1 - 0.015 15.5 2.2 0.031 14.5 2.2 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_28 PF13521.6 PVD30532.1 - 0.018 15.3 0.4 0.032 14.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 PVD30532.1 - 0.022 14.5 0.1 0.11 12.2 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 PVD30532.1 - 0.029 14.1 0.0 0.075 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD30532.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 PVD30532.1 - 0.04 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APG6_N PF17675.1 PVD30532.1 - 0.04 14.4 1.9 0.078 13.5 1.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF815 PF05673.13 PVD30532.1 - 0.042 13.0 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 PVD30532.1 - 0.05 13.2 0.2 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PVD30532.1 - 0.052 13.3 0.3 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PVD30532.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 PVD30532.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 PVD30532.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 PVD30532.1 - 0.088 13.2 0.1 0.53 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PVD30532.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 PVD30532.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 PVD30532.1 - 0.26 11.4 5.2 0.72 10.0 5.2 1.8 1 0 0 1 1 1 0 Hr1 repeat FlxA PF14282.6 PVD30532.1 - 0.77 9.8 3.0 1.4 8.9 2.0 1.8 2 0 0 2 2 2 0 FlxA-like protein MscS_porin PF12795.7 PVD30532.1 - 1.1 8.7 7.7 1.8 8.0 7.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Laminin_G_2 PF02210.24 PVD30533.1 - 9.9e-12 45.5 0.6 2.2e-05 25.0 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD30533.1 - 7.4e-06 26.2 0.1 0.063 13.5 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain IMD PF08397.11 PVD30533.1 - 0.0086 15.5 0.3 0.0086 15.5 0.3 2.8 3 0 0 3 3 3 1 IRSp53/MIM homology domain DUF4908 PF16252.5 PVD30533.1 - 0.028 14.0 2.0 0.025 14.1 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) MetOD2 PF18548.1 PVD30533.1 - 0.29 11.3 11.1 0.53 10.4 0.4 3.1 3 0 0 3 3 3 0 Metanogen output domain 2 DUF948 PF06103.11 PVD30533.1 - 0.42 10.9 8.6 6.1 7.2 0.4 3.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FOXP-CC PF16159.5 PVD30533.1 - 1 10.0 4.5 1.2 9.9 0.5 3.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Med9 PF07544.13 PVD30533.1 - 1.6 8.9 12.9 0.68 10.1 0.3 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 START PF01852.19 PVD30535.1 - 9.4e-15 54.6 1.0 1.3e-14 54.1 1.0 1.2 1 0 0 1 1 1 1 START domain DAGK_cat PF00781.24 PVD30536.1 - 1.4e-21 76.4 0.0 2.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 PVD30536.1 - 0.0079 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RGM_C PF06534.13 PVD30536.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus DEAD PF00270.29 PVD30537.1 - 3.9e-45 153.8 0.0 8.7e-45 152.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD30537.1 - 1.6e-27 96.1 0.0 5.5e-27 94.3 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD30537.1 - 0.00073 19.6 0.1 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PVD30537.1 - 0.0042 16.3 0.0 0.0042 16.3 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S30AE PF02482.19 PVD30537.1 - 0.3 11.9 3.1 11 6.9 0.5 2.9 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Mpp10 PF04006.12 PVD30537.1 - 0.43 9.0 24.7 0.63 8.4 24.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Sec63 PF02889.16 PVD30538.1 - 1.2e-175 581.7 7.7 1.7e-93 312.5 0.8 2.5 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 PVD30538.1 - 2.9e-54 183.5 0.1 3.2e-26 92.2 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 PVD30538.1 - 2.4e-35 121.1 0.1 2.4e-35 121.1 0.1 2.5 3 0 0 3 3 2 1 N-terminal helicase PWI domain ResIII PF04851.15 PVD30538.1 - 2.3e-27 96.1 0.0 6.7e-13 49.0 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PVD30538.1 - 4.2e-18 65.7 0.2 6.1e-08 33.0 0.0 4.8 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PVD30538.1 - 3.8e-07 30.5 0.0 0.076 13.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PVD30538.1 - 1.9e-06 27.7 0.3 0.029 14.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 PVD30538.1 - 0.0014 17.8 0.0 0.89 8.5 0.0 2.8 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_11 PF13086.6 PVD30538.1 - 0.0021 17.9 0.5 0.16 11.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 PVD30538.1 - 0.0032 17.0 0.0 0.76 9.2 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein SWI2_SNF2 PF18766.1 PVD30538.1 - 0.006 16.3 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF603 PF04645.12 PVD30538.1 - 0.0079 15.9 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF603 TcA_RBD PF18518.1 PVD30538.1 - 0.015 15.6 0.1 0.55 10.5 0.0 2.7 2 0 0 2 2 2 0 TcA receptor binding domain UvrD-helicase PF00580.21 PVD30538.1 - 0.079 12.5 0.0 14 5.1 0.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 PVD30538.1 - 0.091 12.3 0.0 7.6 6.0 0.0 3.2 2 1 1 3 3 3 0 P-loop containing dynein motor region SWIB PF02201.18 PVD30539.1 - 8.3e-25 86.5 0.3 2.2e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 PVD30539.1 - 0.0059 16.5 1.9 0.0088 15.9 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain LAP1C PF05609.12 PVD30539.1 - 0.49 9.4 15.2 0.56 9.2 15.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 PVD30539.1 - 2.3 5.2 14.4 2.6 5.1 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DSPc PF00782.20 PVD30540.1 - 3.4e-15 56.0 0.0 5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PVD30540.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PVD30540.1 - 0.043 13.4 0.1 0.092 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase TIR_2 PF13676.6 PVD30541.1 - 1.7e-22 80.3 0.5 1.8e-15 57.6 0.1 3.5 3 1 0 3 3 3 2 TIR domain STALD PF18185.1 PVD30541.1 - 0.0021 17.4 0.1 0.071 12.4 0.0 2.8 2 0 0 2 2 2 1 Sir2- and TIR-associating SLOG family LDcluster4 PF18306.1 PVD30541.1 - 0.15 11.7 0.0 0.58 9.7 0.0 1.9 1 1 0 1 1 1 0 SLOG cluster4 family TIR PF01582.20 PVD30541.1 - 0.22 11.3 1.3 14 5.4 0.0 2.7 2 1 0 2 2 2 0 TIR domain p450 PF00067.22 PVD30542.1 - 3.3e-34 118.4 0.0 1.6e-19 70.1 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 Pox_C4_C10 PF03336.13 PVD30542.1 - 0.082 12.0 0.3 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Poxvirus C4/C10 protein Snf7 PF03357.21 PVD30545.1 - 1.4e-33 115.9 21.3 3e-33 114.9 21.1 1.6 1 1 0 1 1 1 1 Snf7 YqaH PF17448.2 PVD30545.1 - 0.0086 16.4 3.3 0.027 14.8 0.6 2.3 1 1 1 2 2 2 1 Uncharacterized YqaH-like HD_4 PF13328.6 PVD30545.1 - 0.06 13.1 7.0 0.025 14.3 4.5 1.6 1 1 0 1 1 1 0 HD domain PSD4 PF07631.11 PVD30545.1 - 0.23 12.0 4.7 0.32 11.5 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1592) DUF155 PF02582.14 PVD30545.1 - 0.46 10.6 3.4 0.79 9.8 3.4 1.5 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 VSG_B PF13206.6 PVD30545.1 - 0.76 9.0 6.5 1.2 8.3 6.4 1.6 1 1 0 1 1 1 0 Trypanosomal VSG domain Ank_2 PF12796.7 PVD30546.1 - 1.6e-31 108.7 6.2 1.1e-12 48.4 0.3 4.6 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD30546.1 - 2.6e-29 100.4 5.7 5.9e-05 23.3 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 PVD30546.1 - 3.2e-28 97.7 4.3 7.6e-09 36.0 0.0 6.5 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD30546.1 - 2.3e-27 94.7 5.3 5.9e-10 39.2 0.0 7.0 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD30546.1 - 9.4e-27 90.1 12.8 0.00014 22.0 0.0 8.8 10 0 0 10 10 10 6 Ankyrin repeat SOCS_box PF07525.16 PVD30546.1 - 2.8e-11 43.6 5.0 6.9e-11 42.3 5.0 1.7 1 0 0 1 1 1 1 SOCS box JmjC PF02373.22 PVD30548.1 - 1.8e-12 47.7 0.0 8.3e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 PVD30548.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain C1_2 PF03107.16 PVD30548.1 - 0.18 12.1 6.8 0.5 10.7 6.8 1.8 1 0 0 1 1 1 0 C1 domain zf-C5HC2 PF02928.16 PVD30548.1 - 0.4 11.1 11.8 0.96 9.9 11.8 1.6 1 0 0 1 1 1 0 C5HC2 zinc finger Zn_ribbon_17 PF17120.5 PVD30548.1 - 7.4 6.3 11.5 17 5.1 11.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TB2_DP1_HVA22 PF03134.19 PVD30552.1 - 9.4e-28 96.0 9.3 1.8e-27 95.1 9.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 PVD30552.1 - 0.1 12.9 2.2 0.17 12.1 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Aminotran_3 PF00202.21 PVD30553.1 - 1.8e-90 303.5 0.1 3.4e-62 210.4 0.0 3.0 2 1 1 3 3 3 3 Aminotransferase class-III Aminotran_1_2 PF00155.21 PVD30553.1 - 0.045 12.9 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II zf-H2C2_2 PF13465.6 PVD30554.1 - 1.5e-32 110.5 33.2 1.3e-08 34.9 0.3 6.7 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD30554.1 - 1.2e-30 104.2 34.7 9.1e-07 29.0 0.8 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD30554.1 - 2.3e-14 53.2 9.8 0.028 14.7 0.0 5.1 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD30554.1 - 4.5e-12 45.9 22.0 0.049 14.0 0.1 5.7 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 PVD30554.1 - 3.7e-11 42.6 22.6 0.033 14.0 0.9 5.7 5 0 0 5 5 5 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD30554.1 - 1.1e-10 41.4 30.7 0.00036 21.1 1.5 7.1 7 0 0 7 7 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD30554.1 - 9.6e-10 38.2 25.7 0.0026 17.7 1.0 6.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD30554.1 - 1.1e-05 25.1 25.6 0.0015 18.2 0.8 5.1 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PVD30554.1 - 0.002 18.4 18.7 0.58 10.5 0.2 5.3 1 1 4 5 5 5 1 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 PVD30554.1 - 0.014 15.1 10.3 0.74 9.7 0.0 4.1 1 1 3 4 4 4 0 GAGA factor zf-C2H2_9 PF16293.5 PVD30554.1 - 0.029 14.2 7.2 0.96 9.3 0.1 4.5 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 PVD30554.1 - 0.43 10.7 10.9 1.8 8.7 1.3 3.9 3 2 1 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 PVD30554.1 - 0.68 10.0 15.8 1.8 8.6 3.6 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_15 PF17032.5 PVD30554.1 - 0.96 10.2 13.3 2.2 9.1 0.4 3.4 2 1 4 6 6 6 0 zinc-ribbon family zf-C2HC_2 PF13913.6 PVD30554.1 - 1.1 9.2 15.7 17 5.4 0.1 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Elf1 PF05129.13 PVD30554.1 - 1.4 9.0 10.2 0.17 11.9 0.7 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 PVD30554.1 - 1.8 8.6 20.4 0.074 13.0 4.5 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain HypA PF01155.19 PVD30554.1 - 1.8 8.6 7.0 1.5 8.9 1.6 2.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 PVD30554.1 - 3.3 8.0 10.9 1.1 9.5 1.9 3.0 1 1 3 4 4 4 0 TFIIH C1-like domain FdhE PF04216.12 PVD30554.1 - 4.1 7.2 7.8 0.19 11.6 0.6 2.1 2 1 1 3 3 2 0 Protein involved in formate dehydrogenase formation DUF2225 PF09986.9 PVD30554.1 - 8.1 6.1 10.0 2 8.1 0.2 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DZR PF12773.7 PVD30554.1 - 9.7 6.3 12.7 3.4 7.8 1.9 3.1 1 1 1 2 2 2 0 Double zinc ribbon Aldo_ket_red PF00248.21 PVD30555.1 - 8.9e-47 159.7 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_2 PF00535.26 PVD30556.1 - 1.2e-36 126.1 0.0 1.9e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD30556.1 - 8.3e-21 74.6 0.8 1.3e-20 73.9 0.8 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 PVD30556.1 - 4.1e-08 33.4 0.0 7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD30556.1 - 3.8e-06 26.6 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD30556.1 - 5.6e-05 22.7 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ank_2 PF12796.7 PVD30557.1 - 2e-23 82.8 0.3 7.5e-13 48.9 0.0 6.3 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 PVD30557.1 - 8.2e-22 76.6 0.6 1.8e-06 28.1 0.0 7.7 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD30557.1 - 8.2e-21 73.8 0.2 5.5e-05 23.4 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD30557.1 - 1.6e-19 67.9 0.8 8.5e-05 22.7 0.0 8.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 PVD30557.1 - 2.2e-19 69.6 7.1 0.00021 21.8 0.0 7.6 4 1 3 7 7 7 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD30557.1 - 4.2e-05 23.8 1.0 0.00012 22.3 1.0 1.8 1 0 0 1 1 1 1 SOCS box DUF2368 PF10166.9 PVD30557.1 - 0.069 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) bZIP_1 PF00170.21 PVD30558.1 - 2.9e-18 65.7 14.8 7.1e-18 64.5 14.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 PVD30558.1 - 3e-16 58.6 2.2 7.9e-16 57.3 2.2 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 PVD30558.1 - 2.8e-07 30.5 12.8 2.8e-07 30.5 12.8 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD30558.1 - 0.011 16.3 5.6 0.011 16.3 5.6 2.0 2 1 0 2 2 2 0 bZIP Maf transcription factor ASD2 PF08687.11 PVD30558.1 - 0.043 13.4 5.4 0.049 13.2 0.4 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF4988 PF16378.5 PVD30558.1 - 0.16 11.6 1.9 0.35 10.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function Rh5 PF18515.1 PVD30558.1 - 0.44 9.8 5.3 0.14 11.4 1.7 1.8 2 0 0 2 2 2 0 Rh5 coiled-coil domain adh_short PF00106.25 PVD30559.1 - 3.6e-37 127.7 0.0 4.7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30559.1 - 1.3e-23 83.8 0.0 1.8e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD30560.1 - 1.6e-29 102.7 0.0 1.9e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30560.1 - 1.5e-20 73.7 0.0 2e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD30562.1 - 2.2e-70 236.1 0.0 7.4e-38 130.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30562.1 - 4.2e-50 170.5 0.0 1.6e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30562.1 - 1.2e-06 28.6 0.0 0.0066 16.4 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF3155 PF11352.8 PVD30562.1 - 0.017 15.5 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) Fe-S_biosyn PF01521.20 PVD30562.1 - 0.1 12.8 0.2 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Iron-sulphur cluster biosynthesis DUF3611 PF12263.8 PVD30562.1 - 0.54 10.1 3.1 8.4 6.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) adh_short PF00106.25 PVD30563.1 - 3.9e-49 166.8 0.0 2.2e-30 105.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30563.1 - 6.8e-39 133.8 0.0 4.1e-24 85.4 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30563.1 - 0.016 15.1 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 KR domain CBM_10 PF02013.16 PVD30563.1 - 9.9 6.7 7.0 7.4 7.1 0.0 3.3 4 0 0 4 4 4 0 Cellulose or protein binding domain Eno-Rase_NADH_b PF12242.8 PVD30564.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 PVD30564.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 PVD30565.1 - 6.4e-70 234.6 0.0 6.9e-36 123.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30565.1 - 3.7e-50 170.7 0.0 4.5e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3155 PF11352.8 PVD30565.1 - 0.0043 17.4 0.0 9.6 6.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3155) adh_short PF00106.25 PVD30566.1 - 5.1e-29 101.1 0.0 7.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30566.1 - 1.2e-21 77.4 0.0 1.6e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30566.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD30566.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 PVD30567.1 - 3.4e-28 98.4 0.0 4.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30567.1 - 1.8e-21 76.8 0.0 2.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30567.1 - 0.0036 17.3 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD30567.1 - 0.011 15.1 0.0 0.038 13.4 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 PVD30568.1 - 1e-26 93.6 0.0 2e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30568.1 - 9.9e-18 64.5 0.0 1.9e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD30569.1 - 1.1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30569.1 - 1.4e-22 80.4 0.0 1.9e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YL1_C PF08265.11 PVD30570.1 - 3.9e-11 42.5 0.0 9.1e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain YL1_C PF08265.11 PVD30572.1 - 4.1e-08 32.9 0.1 1.1e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 YL1 nuclear protein C-terminal domain Neur_chan_LBD PF02931.23 PVD30573.1 - 3.2e-35 121.5 1.7 2.6e-28 99.0 1.6 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD30573.1 - 5.5e-16 59.3 3.2 5.5e-16 59.3 3.2 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 PVD30574.1 - 1.5e-10 41.6 0.0 1.6e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LRR_4 PF12799.7 PVD30575.1 - 2.2e-15 56.5 35.6 0.00057 20.2 0.1 8.7 3 2 8 11 11 11 8 Leucine Rich repeats (2 copies) UBX PF00789.20 PVD30575.1 - 4.7e-15 55.6 0.0 9.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain LRR_6 PF13516.6 PVD30575.1 - 5.4e-09 35.4 28.8 0.14 12.2 0.1 9.9 11 0 0 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.6 PVD30575.1 - 4.2e-07 29.6 31.4 0.0018 18.0 0.6 6.7 1 1 9 11 11 10 8 Leucine rich repeat DUF4230 PF14014.6 PVD30575.1 - 0.005 17.1 2.7 4.7 7.5 2.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4230) LRR_1 PF00560.33 PVD30575.1 - 1.1 10.0 23.9 12 6.9 0.7 8.2 9 2 0 9 9 9 0 Leucine Rich Repeat Peptidase_S10 PF00450.22 PVD30576.1 - 8.2e-81 272.5 0.9 8.2e-81 272.5 0.9 2.2 2 0 0 2 2 2 1 Serine carboxypeptidase Dus PF01207.17 PVD30576.1 - 1.3e-43 149.3 2.2 1.3e-43 149.2 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 PVD30576.1 - 0.0013 18.5 2.0 0.0013 18.5 2.0 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger PEP_mutase PF13714.6 PVD30576.1 - 0.003 17.0 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Speriolin_C PF15059.6 PVD30576.1 - 0.082 13.0 1.1 0.22 11.6 1.1 1.7 1 0 0 1 1 1 0 Speriolin C-terminus zf-CCCH PF00642.24 PVD30576.1 - 1.1 9.2 24.8 0.04 13.8 5.3 3.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD30576.1 - 3 8.0 20.1 0.87 9.7 6.9 2.8 2 0 0 2 2 2 0 Zinc finger domain Prothymosin PF03247.14 PVD30576.1 - 9.6 6.7 15.5 2.3 8.7 2.6 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Acyltransferase PF01553.21 PVD30577.1 - 1.3e-20 73.3 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RIG-I_C-RD PF11648.8 PVD30578.1 - 5e-20 71.9 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 PVD30578.1 - 8e-20 71.2 0.4 3.2e-19 69.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CARD_2 PF16739.5 PVD30578.1 - 4e-17 62.0 0.4 6.6e-09 35.6 0.0 3.2 2 1 1 3 3 3 2 Caspase recruitment domain DEAD PF00270.29 PVD30578.1 - 7.9e-15 55.1 0.3 2.4e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PVD30578.1 - 2.5e-07 30.9 0.0 6.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD30578.1 - 0.00026 21.3 0.2 0.001 19.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain RIG-I_C PF18119.1 PVD30578.1 - 0.0003 20.8 3.6 0.0005 20.1 0.3 3.0 2 1 0 2 2 2 1 RIG-I receptor C-terminal domain CARD PF00619.21 PVD30578.1 - 0.0028 17.7 1.4 0.78 9.8 0.1 3.5 3 0 0 3 3 3 1 Caspase recruitment domain AAA_22 PF13401.6 PVD30578.1 - 0.0029 17.9 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 PVD30578.1 - 0.039 13.1 0.1 0.085 12.1 0.1 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Syntaxin_2 PF14523.6 PVD30578.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.2 3 0 0 3 3 3 0 Syntaxin-like protein UvrD-helicase PF00580.21 PVD30578.1 - 0.18 11.3 1.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Cu-oxidase_3 PF07732.15 PVD30579.1 - 1.7e-20 73.2 2.6 9.3e-07 28.9 0.0 4.1 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD30579.1 - 3e-16 59.4 14.9 1.6e-08 34.4 4.0 5.8 5 2 0 5 5 5 3 Multicopper oxidase SoxE PF06525.11 PVD30579.1 - 0.13 11.7 0.1 0.52 9.8 0.0 2.0 3 0 0 3 3 3 0 Sulfocyanin (SoxE) domain TFIIA PF03153.13 PVD30579.1 - 0.53 10.2 15.3 0.93 9.4 15.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF21 PF01595.20 PVD30580.1 - 1.4e-39 135.6 1.3 1.4e-39 135.6 1.3 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PVD30580.1 - 0.00073 19.9 1.4 0.18 12.2 0.4 3.0 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 PVD30580.1 - 0.024 14.7 0.0 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Synaptobrevin PF00957.21 PVD30581.1 - 5.3e-15 55.0 0.3 8.1e-15 54.4 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PVD30581.1 - 3e-12 46.4 0.1 1.1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain XRN1_D1 PF18332.1 PVD30581.1 - 0.054 13.3 0.1 0.09 12.5 0.1 1.5 1 1 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain DUF4203 PF13886.6 PVD30582.1 - 1.8e-39 135.5 36.6 2.3e-39 135.2 36.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4094 PF13334.6 PVD30582.1 - 0.37 11.2 3.8 27 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) zf-CCHH PF10283.9 PVD30583.1 - 9.6e-26 89.4 14.7 1.8e-13 50.2 1.0 2.6 2 0 0 2 2 2 2 PBZ domain PARP PF00644.20 PVD30583.1 - 1.1e-15 57.7 0.2 2.8e-14 53.2 0.0 2.4 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain BRCT_2 PF16589.5 PVD30583.1 - 9.3e-06 26.0 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-CCCH PF00642.24 PVD30583.1 - 0.34 10.9 8.3 3 7.9 0.6 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Reticulon PF02453.17 PVD30584.1 - 2.9e-06 27.3 8.2 4.6e-06 26.7 8.2 1.3 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 PVD30584.1 - 0.0028 17.1 8.1 0.005 16.3 8.1 1.4 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) T6PP_N PF18572.1 PVD30584.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Wzy_C PF04932.15 PVD30584.1 - 6.2 6.4 6.5 3.2 7.4 0.7 2.2 2 0 0 2 2 2 0 O-Antigen ligase ABC2_membrane PF01061.24 PVD30584.1 - 9.8 5.5 17.5 1.5 8.2 2.0 2.3 2 0 0 2 2 2 0 ABC-2 type transporter Tubulin PF00091.25 PVD30585.1 - 3.8e-70 236.1 0.0 5.9e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD30585.1 - 3.8e-49 166.1 0.3 7.4e-49 165.1 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PVD30585.1 - 0.00036 20.8 0.0 0.0015 18.8 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PVD30585.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 PVD30585.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Hrs_helical PF12210.8 PVD30585.1 - 0.27 11.8 1.6 0.67 10.5 1.6 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FH2 PF02181.23 PVD30586.1 - 6.3e-102 341.5 9.8 6.3e-102 341.5 9.8 2.8 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD30586.1 - 4.5e-40 137.4 16.1 4.5e-40 137.4 16.1 2.7 2 1 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PVD30586.1 - 4.9e-28 98.0 5.7 4.9e-28 98.0 5.7 4.4 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Waikav_capsid_1 PF12264.8 PVD30586.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Lant_dehydr_N PF04738.13 PVD30586.1 - 0.3 9.1 6.0 0.58 8.2 6.0 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus ZapD PF07072.11 PVD30586.1 - 0.43 10.3 8.4 1.3 8.7 8.4 1.9 1 0 0 1 1 1 0 Cell division protein Med9 PF07544.13 PVD30586.1 - 1.9 8.6 18.2 0.23 11.6 4.3 3.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mito_fiss_reg PF05308.11 PVD30586.1 - 2.7 8.0 30.6 0.26 11.3 0.5 4.1 2 1 1 3 3 3 0 Mitochondrial fission regulator Mt_ATP-synt_D PF05873.12 PVD30586.1 - 3.4 7.5 14.0 0.058 13.2 3.1 2.8 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Baculo_PEP_C PF04513.12 PVD30586.1 - 6.7 6.7 6.1 3.6 7.6 1.8 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aldedh PF00171.22 PVD30587.1 - 5.6e-129 430.6 0.0 7.4e-129 430.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CM_1 PF07736.11 PVD30588.1 - 0.16 12.4 1.5 0.42 11.0 1.5 1.7 1 0 0 1 1 1 0 Chorismate mutase type I RPAP1_N PF08621.10 PVD30588.1 - 7.1 6.5 12.0 3.3 7.5 1.9 3.5 3 0 0 3 3 3 0 RPAP1-like, N-terminal zf-C2H2_2 PF12756.7 PVD30589.1 - 2.1e-07 31.2 1.4 0.043 14.2 0.0 3.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PVD30589.1 - 2.4e-07 30.9 8.4 2.5e-06 27.7 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD30589.1 - 1.4e-05 25.2 10.6 0.002 18.4 0.0 4.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 PVD30589.1 - 0.0011 18.3 7.5 0.057 12.6 0.3 3.2 2 1 1 3 3 3 2 Putative actin-like family EntA_Immun PF08951.10 PVD30589.1 - 0.011 16.1 2.5 0.014 15.7 0.5 2.1 2 0 0 2 2 2 0 Enterocin A Immunity GA-like PF17573.2 PVD30589.1 - 0.031 14.2 0.9 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 GA-like domain zf-C2H2_4 PF13894.6 PVD30589.1 - 0.17 12.8 7.8 18 6.5 0.6 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.12 PVD30589.1 - 0.31 11.2 2.4 2 8.6 0.0 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 PVD30590.1 - 5.8e-34 116.5 23.2 5.6e-27 94.0 6.9 3.5 3 1 0 3 3 2 2 C2H2 type zinc-finger (2 copies) Cytochrom_C PF00034.21 PVD30590.1 - 8.1e-13 49.3 0.2 2.6e-12 47.7 0.0 2.1 2 0 0 2 2 1 1 Cytochrome c zf-C2H2_jaz PF12171.8 PVD30590.1 - 8.4e-13 48.2 9.6 1.7e-10 40.9 2.4 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD30590.1 - 8.8e-09 35.5 7.0 3.9e-08 33.4 3.6 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Cytochrome_CBB3 PF13442.6 PVD30590.1 - 5.8e-06 26.5 0.5 2.9e-05 24.3 0.5 2.3 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III zf-C2H2_6 PF13912.6 PVD30590.1 - 0.00057 19.8 1.9 0.00057 19.8 1.9 3.2 4 0 0 4 4 3 1 C2H2-type zinc finger Cytochrom_C550 PF14495.6 PVD30590.1 - 0.00068 19.4 0.0 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain zf-C2H2 PF00096.26 PVD30590.1 - 0.0016 18.8 2.5 0.0016 18.8 2.5 4.7 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD30590.1 - 0.01 16.6 0.9 0.01 16.6 0.9 4.7 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD30590.1 - 1 10.1 8.3 0.45 11.2 2.1 2.6 2 1 1 3 3 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 PVD30590.1 - 1.1 9.2 5.3 14 5.7 0.3 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-DBF PF07535.12 PVD30590.1 - 4.8 7.4 8.7 0.35 11.0 0.2 2.8 3 0 0 3 3 3 0 DBF zinc finger Ribosomal_L37ae PF01780.19 PVD30591.1 - 9.6e-42 141.0 10.6 1.1e-41 140.8 10.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rsm1 PF08600.10 PVD30591.1 - 0.027 14.6 0.3 0.034 14.3 0.3 1.3 1 0 0 1 1 1 0 Rsm1-like zf-BED PF02892.15 PVD30591.1 - 0.084 12.9 3.7 2.4 8.3 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 PVD30591.1 - 0.096 12.7 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 PVD30591.1 - 0.098 13.1 0.9 4.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain MRNIP PF15749.5 PVD30591.1 - 0.77 10.5 4.7 24 5.7 0.9 2.6 1 1 2 3 3 3 0 MRN-interacting protein Aldo_ket_red PF00248.21 PVD30593.1 - 2.5e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Galactosyl_T PF01762.21 PVD30594.1 - 4.5e-34 118.0 0.0 6.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 PVD30595.1 - 5e-37 127.6 0.0 6.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase F-box-like PF12937.7 PVD30596.1 - 2.2e-11 43.5 2.8 1.7e-10 40.6 0.2 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 PVD30596.1 - 7.2e-08 32.1 0.1 6e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 PVD30596.1 - 0.074 12.6 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 F-box Reprolysin PF01421.19 PVD30597.1 - 9.8e-44 149.7 0.2 1.2e-42 146.0 0.2 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD30597.1 - 6e-16 59.2 0.4 6e-16 59.2 0.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM_CR PF08516.12 PVD30597.1 - 1.1e-12 48.4 0.2 1.1e-12 48.4 0.2 3.4 3 0 0 3 3 3 1 ADAM cysteine-rich Reprolysin_3 PF13582.6 PVD30597.1 - 7.4e-12 45.9 0.3 1.8e-11 44.6 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD30597.1 - 1.9e-09 37.7 0.3 4.8e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD30597.1 - 2.2e-07 31.6 22.2 2.2e-07 31.6 22.2 2.7 3 0 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 PVD30597.1 - 1.6e-06 27.9 1.9 4.9e-06 26.3 1.9 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Zincin_1 PF06262.11 PVD30597.1 - 0.0075 16.3 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M66 PF10462.9 PVD30597.1 - 0.023 13.6 0.5 0.04 12.9 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 PVD30597.1 - 0.098 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Matrixin Peroxin-3 PF04882.12 PVD30599.1 - 3.4 6.6 8.7 4.8 6.1 8.7 1.2 1 0 0 1 1 1 0 Peroxin-3 CDC45 PF02724.14 PVD30599.1 - 6.7 4.9 9.0 7.1 4.8 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.28 PVD30600.1 - 1.1e-35 122.6 0.1 5.4e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain tRNA-synt_2e PF02091.15 PVD30600.1 - 7.4e-05 22.1 0.2 0.19 11.0 0.1 2.6 3 0 0 3 3 3 2 Glycyl-tRNA synthetase alpha subunit Sigma70_r3 PF04539.16 PVD30600.1 - 0.026 14.6 0.9 9.8 6.4 0.1 2.7 3 0 0 3 3 3 0 Sigma-70 region 3 Aldo_ket_red PF00248.21 PVD30601.1 - 8e-41 140.1 0.1 2.5e-35 122.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF953 PF06110.11 PVD30601.1 - 0.054 13.1 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Sec15 PF04091.12 PVD30603.1 - 2.7e-96 322.7 0.9 2.7e-96 322.7 0.9 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Zw10 PF06248.13 PVD30603.1 - 0.0078 14.8 0.7 0.016 13.8 0.7 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps51 PF08700.11 PVD30603.1 - 0.0096 16.0 3.3 0.017 15.2 0.0 3.0 3 0 0 3 3 3 1 Vps51/Vps67 Exo70 PF03081.15 PVD30603.1 - 0.11 11.5 4.2 0.15 11.1 0.1 2.9 3 1 1 4 4 4 0 Exo70 exocyst complex subunit Ras PF00071.22 PVD30604.1 - 2e-43 147.8 0.1 2.3e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD30604.1 - 1e-27 96.8 0.0 1.7e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD30604.1 - 1.7e-12 47.1 0.0 2.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD30604.1 - 4.7e-07 29.4 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD30604.1 - 0.0076 16.3 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 PVD30604.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PVD30604.1 - 0.073 13.0 0.0 9.1 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Aldolase_II PF00596.21 PVD30605.1 - 4.2e-50 170.3 0.2 7e-50 169.5 0.2 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PrmC_N PF17827.1 PVD30605.1 - 0.14 12.8 0.1 0.41 11.3 0.1 1.8 1 0 0 1 1 1 0 PrmC N-terminal domain Anillin_N PF16018.5 PVD30605.1 - 0.62 10.7 9.5 3.5 8.3 1.5 2.9 2 0 0 2 2 2 0 Anillin N-terminus Rhodanese PF00581.20 PVD30606.1 - 1.6e-07 31.8 0.0 1.6e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 PVD30608.1 - 4.2e-40 136.7 0.0 5.3e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 PVD30608.1 - 5.8e-05 23.3 0.0 9.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PVD30608.1 - 0.00057 19.5 0.0 0.00072 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PVD30608.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Myotub-related PF06602.14 PVD30608.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 PVD30608.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD30608.1 - 0.2 11.6 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family COPIIcoated_ERV PF07970.12 PVD30609.1 - 4.6e-33 114.9 0.4 8.2e-33 114.1 0.4 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PVD30609.1 - 4.5e-08 33.3 0.1 4.5e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Haspin_kinase PF12330.8 PVD30610.1 - 3.6e-69 233.5 0.0 5.5e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 PVD30610.1 - 1.8e-06 27.5 0.0 1.1e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PVD30610.1 - 0.038 13.9 0.0 0.19 11.6 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family TFIIF_alpha PF05793.12 PVD30610.1 - 1.1 7.8 13.2 1.7 7.1 13.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Homeodomain PF00046.29 PVD30613.1 - 9.8e-06 25.3 1.7 1.4e-05 24.8 1.7 1.3 1 0 0 1 1 1 1 Homeodomain DUF2931 PF11153.8 PVD30613.1 - 0.16 11.6 0.1 0.17 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) NOA36 PF06524.12 PVD30613.1 - 1.9 7.7 7.0 2 7.6 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein Mtc PF03820.17 PVD30616.1 - 4e-49 167.4 4.1 5.3e-49 167.0 4.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF2222 PF09984.9 PVD30616.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) DB PF01682.19 PVD30617.1 - 0.028 14.7 2.3 0.04 14.2 2.3 1.3 1 1 0 1 1 1 0 DB module ECSCR PF15820.5 PVD30618.1 - 0.0085 15.9 1.2 1.2 9.0 0.2 2.3 1 1 0 2 2 2 2 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 PVD30618.1 - 0.023 14.7 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Protocadherin FAM176 PF14851.6 PVD30618.1 - 0.06 13.0 0.4 0.2 11.3 0.1 1.9 1 1 0 2 2 2 0 FAM176 family EphA2_TM PF14575.6 PVD30618.1 - 0.095 13.6 0.6 0.12 13.3 0.6 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ShK PF01549.24 PVD30619.1 - 3.6e-12 46.6 39.2 0.00011 22.7 8.0 3.2 3 0 0 3 3 3 3 ShK domain-like Rubredoxin_2 PF18073.1 PVD30620.1 - 0.19 11.5 3.3 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain GCIP PF13324.6 PVD30621.1 - 7.5e-09 35.6 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Cadherin_C_2 PF16492.5 PVD30621.1 - 0.013 16.3 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RhoGAP PF00620.27 PVD30622.1 - 1.1e-32 113.0 0.1 1.1e-32 113.0 0.1 1.6 2 0 0 2 2 2 1 RhoGAP domain LCE6A PF15858.5 PVD30622.1 - 0.005 17.6 1.7 0.016 16.0 1.7 1.8 1 0 0 1 1 1 1 Late cornified envelope protein 6A family Virul_Fac PF10139.9 PVD30622.1 - 0.0067 14.7 0.1 0.0087 14.3 0.1 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor 7tm_1 PF00001.21 PVD30624.1 - 2.5e-08 33.6 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD30624.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2700 PF10912.8 PVD30624.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) Herpes_capsid PF06112.11 PVD30624.1 - 5.5 7.0 9.0 9.5 6.3 9.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein LRR_8 PF13855.6 PVD30626.1 - 1.9e-18 66.0 29.5 4.2e-08 32.8 3.4 7.0 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 PVD30626.1 - 8e-10 38.8 33.9 0.015 15.7 2.4 8.8 5 2 6 11 11 11 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD30626.1 - 1.4e-07 32.1 0.0 3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD30626.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD30626.1 - 4.6e-05 23.4 21.4 0.67 10.7 0.0 10.5 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 PVD30626.1 - 0.025 14.6 24.9 8.8 6.7 0.1 10.0 11 0 0 11 11 11 0 Leucine Rich repeat FNIP PF05725.12 PVD30626.1 - 0.15 12.3 0.0 3.5 7.9 0.0 2.8 1 1 0 1 1 1 0 FNIP Repeat LMF1 PF06762.14 PVD30627.1 - 4e-139 464.5 13.4 8.2e-71 239.4 1.1 2.4 2 1 1 3 3 3 2 Lipase maturation factor UPF0154 PF03672.13 PVD30627.1 - 0.058 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TIR_2 PF13676.6 PVD30628.1 - 1.4e-08 35.4 0.0 2.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD30628.1 - 3.7e-07 30.1 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD30629.1 - 5.8e-09 35.6 0.0 7.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD30629.1 - 0.00032 21.0 0.1 0.096 13.2 0.1 2.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD30629.1 - 0.0019 17.7 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat TPKR_C2 PF16920.5 PVD30629.1 - 0.032 14.4 0.7 0.073 13.2 0.4 1.8 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 PVD30629.1 - 0.1 13.2 0.1 21 6.2 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Tetraspanin PF00335.20 PVD30630.1 - 9.2e-58 195.7 20.0 3.5e-35 121.8 7.3 2.6 3 0 0 3 3 3 2 Tetraspanin family DUF4199 PF13858.6 PVD30630.1 - 0.014 15.8 4.8 0.014 15.8 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DNA_pol_A PF00476.20 PVD30634.1 - 1.1e-53 182.7 0.0 1.7e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNApol_Exo PF18136.1 PVD30634.1 - 1.9e-33 115.8 0.6 3e-33 115.2 0.6 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNApol_Exo PF18136.1 PVD30635.1 - 8.2e-54 182.6 0.6 2.2e-53 181.2 0.1 1.7 1 1 1 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DUF829 PF05705.14 PVD30635.1 - 1.5e-19 70.9 0.0 2.9e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) HRM PF02793.22 PVD30637.1 - 8.2e-09 35.6 1.2 8.2e-09 35.6 1.2 1.8 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.24 PVD30639.1 - 1.4e-21 76.9 9.9 1.2e-15 57.5 0.4 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30639.1 - 0.0023 18.2 0.4 0.0046 17.2 0.1 1.6 2 0 0 2 2 2 1 Hormone receptor domain SMRP1 PF15181.6 PVD30639.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 7tm_2 PF00002.24 PVD30640.1 - 4.1e-18 65.6 0.0 5.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Tmemb_185A PF10269.9 PVD30640.1 - 0.033 13.9 0.2 0.046 13.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein 7tm_2 PF00002.24 PVD30641.1 - 1.9e-19 69.9 4.5 2.8e-19 69.4 4.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30641.1 - 0.0016 18.7 0.4 0.0029 17.8 0.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain HRM PF02793.22 PVD30642.1 - 1.3e-07 31.8 0.1 2.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Hormone receptor domain DC_STAMP PF07782.13 PVD30643.1 - 6.2e-16 58.8 0.1 1.8e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 DC-STAMP-like protein NiFeSe_Hases PF00374.19 PVD30643.1 - 0.011 14.7 0.5 0.016 14.1 0.5 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase GST_C_5 PF16865.5 PVD30643.1 - 0.025 15.2 0.0 0.062 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4062 PF13271.6 PVD30644.1 - 3.4e-10 40.1 0.2 1.8e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) TPR_12 PF13424.6 PVD30644.1 - 9.5e-09 35.4 0.3 0.01 16.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 PVD30644.1 - 9e-08 32.7 0.0 4.3e-07 30.5 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 PVD30644.1 - 3.9e-06 26.9 0.0 9.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain MIF4G PF02854.19 PVD30644.1 - 0.0018 18.0 1.2 0.96 9.0 0.0 3.6 3 0 0 3 3 3 1 MIF4G domain AAA_22 PF13401.6 PVD30644.1 - 0.023 15.0 0.0 0.086 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 PVD30644.1 - 0.025 13.8 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 PVD30644.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SPOB_a PF14689.6 PVD30644.1 - 0.11 12.2 0.6 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain MeaB PF03308.16 PVD30644.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 PVD30644.1 - 0.13 12.4 0.0 0.92 9.6 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF4519 PF15012.6 PVD30644.1 - 0.71 10.1 2.6 15 5.8 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4062 PF13271.6 PVD30645.1 - 3.5e-10 40.1 0.2 2e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) TPR_12 PF13424.6 PVD30645.1 - 4.6e-08 33.2 0.2 0.02 15.1 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 PVD30645.1 - 7.6e-08 32.9 0.0 3.4e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PVD30645.1 - 9.7e-07 28.8 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MIF4G PF02854.19 PVD30645.1 - 0.003 17.2 0.9 2.4 7.8 0.0 3.7 4 0 0 4 4 4 1 MIF4G domain AAA_30 PF13604.6 PVD30645.1 - 0.033 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD30645.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 PVD30645.1 - 0.076 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 PVD30645.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SPOB_a PF14689.6 PVD30645.1 - 0.13 12.0 0.6 3 7.6 0.0 2.9 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain MMR_HSR1 PF01926.23 PVD30645.1 - 0.13 12.3 0.0 1.9 8.6 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase 7tm_2 PF00002.24 PVD30647.1 - 7.6e-76 254.6 13.5 1e-75 254.2 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30647.1 - 1.7e-19 69.9 6.1 5e-19 68.4 6.1 1.9 1 0 0 1 1 1 1 Hormone receptor domain Reprolysin PF01421.19 PVD30648.1 - 1.4e-39 136.1 0.0 1.4e-39 136.1 0.0 2.1 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 PVD30648.1 - 1.5e-27 96.6 2.7 2.9e-27 95.6 2.7 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.12 PVD30648.1 - 1.8e-26 92.8 6.7 1.8e-26 92.8 6.7 3.3 3 1 0 4 4 2 1 ADAM cysteine-rich Disintegrin PF00200.23 PVD30648.1 - 2e-18 67.0 26.0 2e-18 67.0 26.0 3.7 5 0 0 5 5 1 1 Disintegrin Reprolysin_5 PF13688.6 PVD30648.1 - 1.2e-11 45.2 0.0 5.4e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD30648.1 - 1.2e-10 42.0 0.1 3.9e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD30648.1 - 3e-05 23.8 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD30648.1 - 3e-05 24.0 0.1 7.4e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 PVD30648.1 - 3.3e-05 24.1 10.5 3.3e-05 24.1 10.5 5.2 5 0 0 5 5 4 1 EGF-like domain Protocadherin PF08374.11 PVD30648.1 - 0.0014 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Protocadherin Peptidase_M43 PF05572.13 PVD30648.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A AP3D1 PF06375.11 PVD30648.1 - 1.3 9.2 5.5 2.4 8.4 1.5 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Kunitz_BPTI PF00014.23 PVD30649.1 - 4.1e-17 62.1 11.3 5.9e-17 61.7 11.3 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain BTB PF00651.31 PVD30650.1 - 6.9e-30 103.5 0.3 1.4e-15 57.5 0.1 3.4 3 0 0 3 3 3 3 BTB/POZ domain Ras PF00071.22 PVD30650.1 - 2e-19 69.8 0.0 4.7e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PVD30650.1 - 3.2e-05 24.1 0.0 8.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cofilin_ADF PF00241.20 PVD30651.1 - 1.9e-21 76.1 0.1 4.4e-21 74.9 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 PVD30651.1 - 3.6e-16 58.7 0.2 6.6e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD30651.1 - 1.3e-14 53.5 0.3 2.9e-14 52.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD30651.1 - 6.2e-10 38.6 0.0 1.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DUF3336 PF11815.8 PVD30651.1 - 3.7 7.3 14.9 1.9 8.2 12.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3336) ALMT PF11744.8 PVD30651.1 - 8.7 5.1 10.5 13 4.5 10.5 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter HflK_N PF12221.8 PVD30652.1 - 0.014 15.4 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal RAWUL PF16207.5 PVD30653.1 - 1.2e-09 38.6 0.3 1.9e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like RAWUL PF16207.5 PVD30654.1 - 5.9e-12 46.1 0.3 9.7e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF3337 PF11816.8 PVD30654.1 - 0.0042 17.0 0.4 0.01 15.7 0.1 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) DERM PF14704.6 PVD30655.1 - 3.4e-19 69.8 0.0 4.5e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Dermatopontin Cpn60_TCP1 PF00118.24 PVD30656.1 - 2.1e-134 448.9 2.4 4.6e-134 447.7 2.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DERM PF14704.6 PVD30656.1 - 9.3e-17 61.9 2.3 1.8e-16 61.0 2.3 1.4 1 0 0 1 1 1 1 Dermatopontin GDA1_CD39 PF01150.17 PVD30657.1 - 1.5e-98 330.3 0.4 1.9e-98 329.9 0.4 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4064 PF13273.6 PVD30657.1 - 0.011 15.9 4.3 0.3 11.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FtsX PF02687.21 PVD30657.1 - 0.29 11.6 2.7 12 6.5 0.8 2.5 2 0 0 2 2 2 0 FtsX-like permease family ARID PF01388.21 PVD30658.1 - 2.4e-18 66.6 0.1 6.1e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rhodanese PF00581.20 PVD30658.1 - 2.7e-11 43.9 0.0 1e-10 42.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain zf-RING_2 PF13639.6 PVD30659.1 - 1.5e-12 47.6 13.9 4e-12 46.3 13.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD30659.1 - 2e-07 31.2 9.1 2e-07 31.2 9.1 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD30659.1 - 8.5e-07 28.6 9.6 2.2e-06 27.3 9.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD30659.1 - 1.1e-05 25.1 13.5 2.6e-05 24.0 13.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD30659.1 - 5.7e-05 22.9 12.7 0.00011 21.9 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30659.1 - 6.4e-05 22.8 11.5 0.00012 21.9 11.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD30659.1 - 0.00076 19.3 11.3 0.0014 18.4 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PVD30659.1 - 0.0029 17.6 4.9 0.0079 16.2 4.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PVD30659.1 - 0.028 14.4 9.3 0.073 13.1 9.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PVD30659.1 - 0.27 10.9 10.1 0.51 10.0 10.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PVD30659.1 - 1.2 9.4 7.5 3 8.1 7.5 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 PVD30659.1 - 8.1 6.7 12.8 16 5.8 12.8 1.5 1 0 0 1 1 1 0 RING-variant domain MAP65_ASE1 PF03999.12 PVD30660.1 - 3.3e-117 392.7 36.9 4.3e-117 392.3 36.9 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DMPK_coil PF08826.10 PVD30660.1 - 0.12 12.5 0.3 0.12 12.5 0.3 5.6 6 0 0 6 6 6 0 DMPK coiled coil domain like NPH3 PF03000.14 PVD30661.1 - 2.8e-22 79.6 3.3 2.5e-13 50.3 0.4 2.3 1 1 1 2 2 2 2 NPH3 family BTB PF00651.31 PVD30661.1 - 3.7e-11 43.3 0.0 1.4e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain FAM212 PF15342.6 PVD30661.1 - 0.15 11.9 0.7 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 FAM212 family Glyco_hydro_59 PF02057.15 PVD30662.1 - 8e-112 373.3 2.6 1.1e-111 372.8 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 PVD30662.1 - 7.1e-48 161.6 0.1 1.5e-47 160.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain UBD PF16455.5 PVD30663.1 - 2.6e-38 130.4 0.0 4.3e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 PVD30663.1 - 5e-14 51.8 0.0 7.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD30663.1 - 1.3e-05 24.9 0.1 2.8e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PVD30663.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 PVD30663.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WD40 PF00400.32 PVD30664.1 - 8.3e-08 32.8 9.5 0.022 15.6 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD30664.1 - 1.4e-06 28.5 0.0 0.003 17.8 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MSP7_C PF12948.7 PVD30664.1 - 0.19 12.4 4.1 0.44 11.2 4.1 1.5 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Fez1 PF06818.15 PVD30665.1 - 5.4e-18 66.2 25.0 8.3e-18 65.6 6.9 2.3 2 0 0 2 2 2 2 Fez1 PKcGMP_CC PF16808.5 PVD30665.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 2.5 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 PVD30665.1 - 0.0057 17.2 13.9 0.0057 17.2 13.9 2.6 2 0 0 2 2 2 1 Apg6 coiled-coil region KASH_CCD PF14662.6 PVD30665.1 - 0.0065 16.3 31.1 0.016 15.0 15.6 3.4 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH RNA_lig_T4_1 PF09511.10 PVD30665.1 - 0.064 13.1 5.1 0.25 11.2 0.3 2.2 2 0 0 2 2 2 0 RNA ligase FapA PF03961.13 PVD30665.1 - 0.35 9.4 11.8 0.018 13.7 0.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Nmad5 PF18757.1 PVD30665.1 - 0.43 10.7 8.0 0.1 12.8 0.7 2.4 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 TryThrA_C PF12319.8 PVD30665.1 - 3.3 7.1 10.3 1.5 8.2 2.5 2.2 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal JAKMIP_CC3 PF16034.5 PVD30665.1 - 3.4 7.6 21.5 6.1 6.7 6.9 2.7 2 0 0 2 2 2 0 JAKMIP CC3 domain Homeodomain PF00046.29 PVD30666.1 - 3.3e-20 71.7 3.4 6.1e-20 70.8 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD30666.1 - 0.025 14.0 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 PVD30666.1 - 0.082 12.8 0.1 5.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeodomain PF00046.29 PVD30668.1 - 1.1e-08 34.7 0.5 2.1e-08 33.9 0.5 1.5 1 0 0 1 1 1 1 Homeodomain 7tm_2 PF00002.24 PVD30673.1 - 9.3e-40 136.5 4.3 1.2e-39 136.1 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 PVD30673.1 - 1.7e-06 27.4 5.8 2.2e-06 27.0 5.8 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 PVD30673.1 - 0.0032 16.6 5.4 0.0044 16.1 5.4 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Phage_holin_5_2 PF16079.5 PVD30673.1 - 0.017 15.5 0.2 0.055 13.8 0.2 1.9 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Herpes_UL73 PF03554.13 PVD30673.1 - 0.33 11.0 5.7 1 9.4 0.3 2.7 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Lectin_C PF00059.21 PVD30674.1 - 5.7e-08 33.5 0.0 9.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD30674.1 - 0.089 12.4 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-C3HC4_3 PF13920.6 PVD30675.1 - 0.00023 21.0 7.9 0.00056 19.7 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IFT57 PF10498.9 PVD30675.1 - 0.0018 17.3 9.7 0.0018 17.3 9.7 1.6 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 zf-RING_UBOX PF13445.6 PVD30675.1 - 0.0022 18.0 6.2 0.0063 16.5 6.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger CENP-F_leu_zip PF10473.9 PVD30675.1 - 0.0066 16.5 15.8 0.016 15.3 15.8 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4 PF00097.25 PVD30675.1 - 0.0098 15.7 9.0 0.013 15.3 6.9 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD30675.1 - 0.032 14.2 8.9 0.1 12.6 8.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 PVD30675.1 - 0.037 14.4 9.6 0.11 12.9 9.6 1.9 1 0 0 1 1 1 0 Ring finger domain DUF3450 PF11932.8 PVD30675.1 - 0.041 13.2 12.7 0.1 11.9 12.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prok-RING_4 PF14447.6 PVD30675.1 - 0.088 12.7 9.8 0.11 12.4 7.6 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD30675.1 - 0.22 11.4 8.8 1.1 9.1 9.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 PVD30675.1 - 0.45 9.0 16.6 0.62 8.5 15.9 1.4 1 1 0 1 1 1 0 Macoilin family zf-RING_10 PF16685.5 PVD30675.1 - 0.78 9.9 10.9 0.25 11.5 7.0 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Yuri_gagarin PF15934.5 PVD30675.1 - 1.1 9.1 16.2 0.49 10.2 9.9 2.5 1 1 1 2 2 2 0 Yuri gagarin GAS PF13851.6 PVD30675.1 - 1.1 8.5 28.9 0.058 12.7 20.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 PVD30675.1 - 1.4 8.8 11.5 1 9.3 3.7 2.5 1 1 1 2 2 2 0 Sec34-like family zf-C3HC4_4 PF15227.6 PVD30675.1 - 5.3 7.3 7.1 19 5.5 7.2 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Syntaxin PF00804.25 PVD30675.1 - 5.6 6.6 18.5 0.065 12.9 10.0 2.0 3 0 0 3 3 3 0 Syntaxin FYVE PF01363.21 PVD30675.1 - 5.8 7.1 8.7 4.8e+02 1.0 8.8 3.3 1 1 0 1 1 1 0 FYVE zinc finger APC_N_CC PF16689.5 PVD30675.1 - 9.2 6.4 11.3 2.6 8.2 0.8 3.4 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1295 PF06966.12 PVD30676.1 - 5.4e-61 206.1 5.3 6.3e-61 205.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 PVD30676.1 - 2.8e-05 24.1 1.1 2.8e-05 24.1 1.1 2.5 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 PVD30676.1 - 0.00013 22.4 0.5 0.00089 19.6 0.0 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 PVD30676.1 - 0.002 16.9 4.4 0.0065 15.3 4.4 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 PVD30676.1 - 0.0056 17.1 0.5 0.025 15.0 0.0 2.4 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FERM_C PF09380.10 PVD30683.1 - 4.4e-19 68.7 0.0 7.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD30683.1 - 5.2e-19 68.8 0.1 5.2e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 PVD30683.1 - 3.9e-14 52.3 0.6 7.9e-14 51.4 0.6 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 PVD30683.1 - 1.8e-13 50.3 11.7 1.8e-13 50.3 11.7 2.7 2 0 0 2 2 2 1 FERM adjacent (FA) TT_ORF1 PF02956.14 PVD30683.1 - 3.8 6.1 9.2 6.2 5.4 9.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 YwiC PF14256.6 PVD30684.1 - 3.9 7.8 5.5 1.1 9.6 0.9 2.0 2 0 0 2 2 2 0 YwiC-like protein PEHE PF15275.6 PVD30685.1 - 3.5e-21 76.2 1.8 3.5e-21 76.2 1.8 2.8 2 1 1 3 3 3 1 PEHE domain MSL1_dimer PF16801.5 PVD30685.1 - 0.013 15.2 8.6 0.045 13.5 8.6 1.9 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 WD40 PF00400.32 PVD30686.1 - 5e-33 112.6 28.0 5.9e-07 30.1 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 PVD30686.1 - 2e-19 69.8 0.6 4e-19 68.9 0.6 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 PVD30686.1 - 4.7e-05 23.6 6.5 0.071 13.4 0.2 4.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_4 PF08386.10 PVD30686.1 - 0.12 12.5 0.2 0.52 10.5 0.1 2.0 2 0 0 2 2 2 0 TAP-like protein Nup160 PF11715.8 PVD30686.1 - 0.27 9.8 7.9 0.42 9.2 1.4 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 RhoGAP PF00620.27 PVD30687.1 - 3.8e-47 159.9 0.1 6.7e-47 159.1 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 PVD30687.1 - 6.5e-08 33.0 0.1 1.9e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 PVD30687.1 - 1.8e-07 30.6 0.3 5e-07 29.2 0.3 1.8 1 0 0 1 1 1 1 SH3 domain WW PF00397.26 PVD30687.1 - 6.8e-07 29.3 5.0 0.0065 16.5 0.8 2.5 2 0 0 2 2 2 2 WW domain SH3_9 PF14604.6 PVD30687.1 - 7.9e-07 28.8 0.6 2e-06 27.6 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain RPEL PF02755.15 PVD30687.1 - 4.9e-06 26.1 0.1 8.9e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 RPEL repeat PH_9 PF15410.6 PVD30687.1 - 3.9e-05 24.0 0.0 8.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PVD30687.1 - 0.054 13.9 0.2 0.19 12.1 0.2 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.22 PVD30689.1 - 2.2e-75 254.2 0.2 2.9e-75 253.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRS1 PF04939.12 PVD30689.1 - 0.14 12.0 0.4 3.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Ribosome biogenesis regulatory protein (RRS1) FERM_M PF00373.18 PVD30690.1 - 4.1e-23 82.0 0.2 8.4e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PVD30690.1 - 1.2e-21 76.4 0.4 8.6e-20 70.5 0.2 2.3 2 0 0 2 2 2 2 FERM N-terminal domain DUF1853 PF08907.11 PVD30690.1 - 0.029 14.1 0.2 0.059 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) Y_phosphatase PF00102.27 PVD30691.1 - 7.9e-65 218.7 0.1 1.6e-64 217.7 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 PVD30691.1 - 1.4e-26 92.7 0.2 4.5e-26 91.1 0.2 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD30691.1 - 2.7e-22 79.4 0.2 8.9e-22 77.7 0.2 2.0 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PVD30691.1 - 3.6e-20 71.7 0.6 6.4e-19 67.7 0.2 2.5 2 0 0 2 2 2 1 FERM N-terminal domain PDZ PF00595.24 PVD30691.1 - 5.8e-19 68.2 0.0 1.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FA PF08736.11 PVD30691.1 - 9.5e-16 57.6 10.7 2.6e-15 56.2 10.7 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) PDZ_6 PF17820.1 PVD30691.1 - 3.6e-05 23.5 0.0 7.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 PVD30691.1 - 0.0022 17.8 0.0 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD30691.1 - 0.0034 17.4 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ_2 PF13180.6 PVD30691.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PTPlike_phytase PF14566.6 PVD30691.1 - 0.11 12.6 0.6 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF1180 PF06679.12 PVD30692.1 - 0.0066 16.9 0.2 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Wzy_C_2 PF11846.8 PVD30692.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Kisspeptin PF15152.6 PVD30692.1 - 1.6 9.6 3.7 2.6 8.9 0.5 2.9 2 1 1 3 3 3 0 Kisspeptin SPATA24 PF15175.6 PVD30693.1 - 5.6e-29 101.3 24.3 8e-29 100.8 24.3 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Spc7 PF08317.11 PVD30693.1 - 0.16 10.8 25.0 0.087 11.7 22.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 PVD30693.1 - 0.43 10.0 27.8 0.62 9.5 27.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2730 PF10805.8 PVD30693.1 - 0.57 10.3 12.5 0.48 10.5 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4806 PF16064.5 PVD30693.1 - 0.95 9.8 9.9 4 7.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) FUSC PF04632.12 PVD30693.1 - 1.5 7.3 5.2 1.9 7.0 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 PVD30693.1 - 1.8 7.1 11.1 2.4 6.7 11.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CREPT PF16566.5 PVD30693.1 - 2.3 8.4 22.1 6.1 7.0 8.2 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 PVD30693.1 - 2.7 7.3 11.6 4.1 6.7 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 PVD30693.1 - 3.2 7.8 26.6 0.03 14.4 14.2 2.4 1 1 1 2 2 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 PVD30693.1 - 3.4 7.7 18.0 0.03 14.3 4.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 PVD30693.1 - 6.3 5.6 9.0 7.8 5.3 9.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 PVD30693.1 - 8.7 6.4 32.0 2.8 8.0 18.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup_retrotrp_bd PF10599.9 PVD30695.1 - 0.017 15.7 1.2 0.036 14.7 1.2 1.4 1 0 0 1 1 1 0 Retro-transposon transporting motif Methyltransf_FA PF12248.8 PVD30697.1 - 9.5e-18 64.4 0.1 3e-17 62.8 0.1 1.8 1 1 1 2 2 2 1 Farnesoic acid 0-methyl transferase FTCD_N PF07837.12 PVD30698.1 - 6e-64 215.1 0.0 1.1e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 PVD30698.1 - 1.5e-52 177.5 0.4 3.1e-52 176.5 0.1 1.6 2 0 0 2 2 2 1 Formiminotransferase domain FTCD_C PF04961.12 PVD30698.1 - 1.2e-35 122.9 0.3 1.5e-25 90.0 0.1 2.5 1 1 1 2 2 2 2 Formiminotransferase-cyclodeaminase Bromodomain PF00439.25 PVD30699.1 - 1.2e-06 28.5 0.0 3.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 PVD30699.1 - 0.00013 22.3 0.1 0.00013 22.3 0.1 3.8 4 2 0 4 4 4 1 PWWP domain zf-MYND PF01753.18 PVD30699.1 - 0.0065 16.5 22.5 0.0065 16.5 22.5 3.8 3 1 0 3 3 3 1 MYND finger PHD PF00628.29 PVD30699.1 - 0.009 15.9 8.3 0.009 15.9 8.3 4.3 3 1 1 4 4 4 1 PHD-finger PET10 PF17316.2 PVD30699.1 - 0.14 11.7 3.7 0.36 10.3 3.7 1.7 1 0 0 1 1 1 0 Petite colonies protein 10 Mitofilin PF09731.9 PVD30699.1 - 2 7.1 36.2 3.1 6.5 36.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Rpr2 PF04032.16 PVD30699.1 - 3.5 8.0 15.2 0.24 11.7 7.5 3.2 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Spore_III_AB PF09548.10 PVD30699.1 - 4.9 7.2 16.5 0.087 12.9 6.6 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) ARGLU PF15346.6 PVD30699.1 - 8.4 6.3 34.1 0.065 13.1 18.0 2.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 His_Phos_2 PF00328.22 PVD30700.1 - 1.5e-24 87.1 0.1 7.8e-14 51.8 0.0 3.2 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) DAG1 PF05454.11 PVD30700.1 - 0.19 11.1 0.3 0.41 10.0 0.1 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Kinesin PF00225.23 PVD30701.1 - 7.9e-113 376.8 0.6 7.9e-113 376.8 0.6 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD30701.1 - 2.2e-26 92.6 2.5 4.5e-26 91.6 0.0 2.9 2 1 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 PVD30701.1 - 0.11 11.4 99.8 0.26 10.1 26.7 4.5 2 1 2 4 4 4 0 Spc7 kinetochore protein ANAPC16 PF17256.2 PVD30701.1 - 4.5 7.7 6.8 1.8 9.0 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, subunit 16 DUF4283 PF14111.6 PVD30702.1 - 0.094 12.2 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) V-SNARE_C PF12352.8 PVD30702.1 - 0.095 13.0 0.9 13 6.2 0.2 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.14 PVD30702.1 - 0.098 12.4 3.0 0.11 12.1 0.5 2.3 2 1 0 2 2 2 0 Laminin Domain I Pkinase PF00069.25 PVD30705.1 - 1.7e-59 201.4 0.0 2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30705.1 - 3.6e-45 154.3 0.1 5.1e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 PVD30705.1 - 8.3e-21 74.0 0.2 1.6e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 PVD30705.1 - 2.8e-05 23.1 0.0 4.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD30705.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD30705.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3294 PF07957.11 PVD30705.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) L27 PF02828.16 PVD30706.1 - 0.42 10.4 3.7 0.51 10.1 0.1 3.0 3 0 0 3 3 3 0 L27 domain MBOAT PF03062.19 PVD30707.1 - 6.5e-40 137.6 33.9 9.7e-40 137.0 33.9 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PVD30707.1 - 0.0042 17.3 5.0 0.0042 17.3 5.0 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Ribosomal_L36e PF01158.18 PVD30708.1 - 0.03 14.6 1.2 0.054 13.7 0.3 1.9 2 0 0 2 2 2 0 Ribosomal protein L36e Retrotrans_gag PF03732.17 PVD30708.1 - 0.13 12.6 1.7 0.35 11.2 1.7 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein Striatin PF08232.12 PVD30708.1 - 0.26 11.9 7.7 0.42 11.2 7.7 1.3 1 0 0 1 1 1 0 Striatin family Phosducin PF02114.16 PVD30708.1 - 0.46 9.4 7.6 0.76 8.7 7.6 1.4 1 1 0 1 1 1 0 Phosducin Glyco_transf_92 PF01697.27 PVD30711.1 - 8.2e-33 114.1 0.0 1.6e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD30711.1 - 1.7e-05 25.2 0.0 6.1e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 7tm_1 PF00001.21 PVD30712.1 - 6.3e-27 94.5 4.4 7.5e-27 94.3 4.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD30712.1 - 3.3e-09 36.5 19.6 1.8e-05 24.2 1.5 3.0 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD30712.1 - 4.6e-05 22.9 5.2 4.6e-05 22.9 5.2 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD30712.1 - 0.0004 20.1 10.4 0.0004 20.1 10.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Glyco_transf_92 PF01697.27 PVD30713.1 - 1.6e-32 113.2 0.0 2.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD30713.1 - 1.1e-05 25.9 0.0 3.9e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cnd3 PF12719.7 PVD30714.1 - 4.5e-70 236.2 2.1 4.5e-70 236.2 2.1 3.3 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 PVD30714.1 - 8e-12 44.4 5.9 1.1 9.7 0.0 8.2 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 PVD30714.1 - 8.5e-09 35.7 2.3 0.028 14.8 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats UVR PF02151.19 PVD30714.1 - 4.2e-05 23.2 2.5 0.00011 21.8 2.5 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif HEAT_EZ PF13513.6 PVD30714.1 - 5e-05 23.7 2.0 0.12 12.9 0.2 4.6 3 1 1 4 4 4 2 HEAT-like repeat HlyD_2 PF12700.7 PVD30714.1 - 0.0056 15.5 3.3 0.0094 14.7 3.3 1.2 1 0 0 1 1 1 1 HlyD family secretion protein DUF5560 PF17715.1 PVD30714.1 - 0.1 12.0 0.4 0.2 11.1 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Cnd1 PF12717.7 PVD30714.1 - 0.6 10.1 16.9 0.22 11.5 0.1 5.3 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF4404 PF14357.6 PVD30714.1 - 1 10.0 9.2 12 6.6 0.6 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) c-SKI_SMAD_bind PF08782.10 PVD30715.1 - 8.9e-06 25.9 0.1 2.8e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Ski_Sno PF02437.17 PVD30715.1 - 0.034 13.9 0.2 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 SKI/SNO/DAC family Peptidase_M13_N PF05649.13 PVD30717.1 - 2.5e-73 248.0 0.0 3.2e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD30717.1 - 2.6e-63 213.3 0.1 4.6e-63 212.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 PVD30717.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 DEP PF00610.21 PVD30718.1 - 1.6e-06 28.1 0.2 2e-05 24.6 0.2 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Membr_traf_MHD PF10540.9 PVD30718.1 - 0.021 15.0 3.5 2.5 8.2 0.2 3.0 1 1 1 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 PVD30718.1 - 0.08 13.4 0.4 0.47 10.9 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Neur_chan_LBD PF02931.23 PVD30719.1 - 1.4e-10 41.0 3.9 2.2e-10 40.4 3.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Conotoxin PF02950.17 PVD30719.1 - 0.012 16.6 0.5 5.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Conotoxin Neur_chan_memb PF02932.16 PVD30719.1 - 0.037 14.1 9.6 0.087 12.9 9.6 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 PVD30719.1 - 1.4 9.0 9.4 1.1 9.4 2.4 2.4 1 1 0 2 2 2 0 GWT1 DUF2070 PF09843.9 PVD30719.1 - 8.7 4.5 13.4 13 3.9 13.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NHL PF01436.21 PVD30720.1 - 9.2e-09 34.9 1.3 1.9 8.7 0.0 5.7 6 0 0 6 6 6 3 NHL repeat zf-B_box PF00643.24 PVD30720.1 - 0.0014 18.7 8.8 0.0014 18.7 8.8 2.1 2 0 0 2 2 2 1 B-box zinc finger DASH_Spc19 PF08287.11 PVD30720.1 - 0.0076 16.2 7.5 0.45 10.4 1.9 2.3 1 1 1 2 2 2 2 Spc19 Laminin_II PF06009.12 PVD30720.1 - 0.085 12.9 1.3 0.14 12.2 0.3 1.8 1 1 1 2 2 2 0 Laminin Domain II PRiA4_ORF3 PF07929.11 PVD30720.1 - 0.13 12.0 0.4 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein ING PF12998.7 PVD30720.1 - 1.3 9.6 6.8 9.3 6.9 3.3 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_C48 PF02902.19 PVD30722.1 - 5.8e-44 150.5 1.8 5.8e-44 150.5 1.8 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 PVD30722.1 - 0.00011 21.0 4.7 0.019 13.7 4.7 2.2 1 1 0 1 1 1 1 Vaccinia virus I7 processing peptidase Neuraminidase PF18413.1 PVD30722.1 - 0.034 13.8 0.5 0.076 12.7 0.5 1.5 1 0 0 1 1 1 0 Neuraminidase-like domain Peptidase_C5 PF00770.18 PVD30722.1 - 0.17 11.6 0.7 0.34 10.6 0.7 1.4 1 0 0 1 1 1 0 Adenovirus endoprotease Nucleos_tra2_C PF07662.13 PVD30723.1 - 2e-58 197.7 7.0 2e-58 197.7 7.0 2.7 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30723.1 - 1e-21 77.3 2.9 1e-21 77.3 2.9 3.3 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD30723.1 - 3.2e-05 24.2 8.5 3.2e-05 24.2 8.5 3.6 4 0 0 4 4 4 1 Nucleoside recognition FNIP_N PF14636.6 PVD30724.1 - 0.087 13.8 1.0 0.13 13.2 0.2 1.6 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Nucleos_tra2_C PF07662.13 PVD30725.1 - 6.4e-76 254.8 6.3 6.4e-76 254.8 6.3 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30725.1 - 1.6e-20 73.5 2.5 1.6e-20 73.5 2.5 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD30725.1 - 2.3e-05 24.6 10.3 2.3e-05 24.6 10.3 3.0 3 0 0 3 3 3 1 Nucleoside recognition Cyt-b5 PF00173.28 PVD30726.1 - 5.4e-14 52.1 0.3 1.1e-13 51.1 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltr_RsmB-F PF01189.17 PVD30727.1 - 3.6e-44 150.8 0.0 5.1e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 PVD30727.1 - 1.3e-05 25.0 0.0 4.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 PVD30727.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 PVD30727.1 - 0.0049 17.5 0.0 0.017 15.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD30727.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 PVD30727.1 - 0.21 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin VWC PF00093.18 PVD30728.1 - 8.8e-05 22.7 32.3 0.033 14.5 11.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type C domain TRAPPC-Trs85 PF12739.7 PVD30730.1 - 0.059 12.3 0.4 0.075 12.0 0.4 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ribosomal_60s PF00428.19 PVD30730.1 - 0.11 13.1 0.2 0.11 13.1 0.2 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HLH PF00010.26 PVD30731.1 - 1.1e-16 60.5 0.3 1.8e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 PVD30731.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain DUF773 PF05600.12 PVD30731.1 - 0.37 9.5 5.6 0.057 12.2 0.4 1.8 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 zf-C2H2_assoc2 PF16624.5 PVD30731.1 - 8.6 7.5 10.8 5.8 8.0 6.9 2.7 1 1 1 2 2 2 0 Unstructured region upstream of a zinc-finger HLH PF00010.26 PVD30732.1 - 1.1e-16 60.5 0.3 2.2e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 PVD30732.1 - 0.0077 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 PVD30732.1 - 0.023 13.4 0.4 0.031 13.0 0.4 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 VWC PF00093.18 PVD30734.1 - 9e-05 22.7 6.5 9e-05 22.7 6.5 2.3 2 1 1 3 3 3 1 von Willebrand factor type C domain SOG2 PF10428.9 PVD30734.1 - 0.16 11.2 14.5 0.18 11.0 14.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4648 PF15505.6 PVD30734.1 - 0.66 10.9 3.5 37 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) VWC PF00093.18 PVD30736.1 - 0.95 9.8 13.3 0.58 10.5 10.8 2.0 2 0 0 2 2 2 0 von Willebrand factor type C domain Prp19 PF08606.11 PVD30740.1 - 0.0028 17.6 0.2 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like MtrG PF04210.13 PVD30740.1 - 0.12 12.3 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cullin PF00888.22 PVD30741.1 - 1.7e-160 535.7 6.6 2.4e-160 535.1 6.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PVD30741.1 - 1.5e-26 92.2 2.4 4.6e-26 90.6 2.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 PVD30741.1 - 0.051 14.2 0.1 0.17 12.5 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_20 PF12840.7 PVD30741.1 - 0.15 12.2 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_1 PF00515.28 PVD30742.1 - 1.4e-37 125.9 23.1 5.9e-07 29.0 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 PVD30742.1 - 8.3e-32 106.7 21.5 5.9e-05 22.9 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat RPAP3_C PF13877.6 PVD30742.1 - 1.1e-17 64.3 0.0 5.1e-17 62.2 0.0 2.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_12 PF13424.6 PVD30742.1 - 9.3e-16 57.9 16.7 0.00012 22.3 0.0 7.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD30742.1 - 4.1e-14 51.5 19.1 0.0023 18.0 0.1 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD30742.1 - 1.9e-12 46.6 17.6 6.1e-06 25.8 0.1 6.9 5 2 2 7 7 7 4 TPR repeat TPR_9 PF13371.6 PVD30742.1 - 1.5e-10 41.0 5.3 0.037 14.2 0.2 4.8 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 PVD30742.1 - 1.7e-10 41.4 0.1 0.11 13.2 0.0 4.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 PVD30742.1 - 2.4e-10 40.8 4.3 0.017 15.6 1.6 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD30742.1 - 2.1e-08 34.0 22.8 0.0013 19.0 0.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD30742.1 - 2.1e-08 34.3 11.0 0.33 11.9 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD30742.1 - 3.8e-08 32.8 10.7 0.12 12.5 0.3 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD30742.1 - 8.1e-07 29.0 17.3 0.0029 17.6 0.5 4.9 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 PVD30742.1 - 9.7e-06 25.9 15.1 2.2 9.1 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat BTAD PF03704.17 PVD30742.1 - 9.8e-06 26.1 3.0 0.00048 20.6 0.9 3.6 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 PVD30742.1 - 0.00021 21.1 3.4 0.096 12.6 0.3 5.0 6 0 0 6 6 3 1 Tetratricopeptide repeat Phospholamban PF04272.14 PVD30742.1 - 0.029 13.9 0.4 23 4.6 0.0 3.8 3 0 0 3 3 3 0 Phospholamban MIT PF04212.18 PVD30742.1 - 0.041 14.0 0.1 0.041 14.0 0.1 6.3 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 PVD30742.1 - 0.42 10.7 3.6 6.7 6.8 0.3 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Pribosyl_synth PF14572.6 PVD30743.1 - 2.1e-38 132.2 0.4 4.7e-34 118.0 0.3 2.0 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PVD30743.1 - 4.2e-10 39.4 0.2 5.3e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PVD30743.1 - 0.0033 16.9 0.2 0.0043 16.5 0.2 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 PVD30743.1 - 0.012 15.7 0.8 0.018 15.0 0.5 1.5 1 1 0 1 1 1 0 Chlorosome envelope protein C CDK5_activator PF03261.15 PVD30744.1 - 2.7e-104 349.6 14.2 1e-97 328.0 5.8 2.0 1 1 1 2 2 2 2 Cyclin-dependent kinase 5 activator protein AA_kinase PF00696.28 PVD30746.1 - 7.3e-07 29.0 0.0 8.2e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Methyltransf_16 PF10294.9 PVD30747.1 - 1.2e-06 28.4 0.1 2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PVD30747.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_T4_N PF04491.12 PVD30747.1 - 0.2 11.5 1.3 0.39 10.6 1.3 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus zf-TFIIIC PF12660.7 PVD30748.1 - 2e-07 30.9 2.4 2e-07 30.9 2.4 2.5 2 1 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 PVD30748.1 - 0.025 14.9 0.5 18 5.7 0.0 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FYVE_2 PF02318.16 PVD30748.1 - 0.34 11.1 9.4 1.8 8.8 1.9 3.0 2 0 0 2 2 2 0 FYVE-type zinc finger bVLRF1 PF18826.1 PVD30749.1 - 8.5e-53 178.2 1.6 1e-52 178.0 0.0 2.0 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor VATC PF18716.1 PVD30749.1 - 9.7e-11 41.3 6.9 9.7e-11 41.3 6.9 2.2 3 0 0 3 3 3 1 Vms1-associating treble clef domain Kunitz_BPTI PF00014.23 PVD30750.1 - 3.9e-134 436.9 121.9 9.2e-20 70.6 7.8 10.0 6 3 3 9 9 9 9 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3915 PF13054.6 PVD30750.1 - 0.00046 20.2 4.9 0.0012 18.8 4.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Peptidase_S49_N PF08496.10 PVD30750.1 - 0.7 9.9 3.2 1.2 9.2 3.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Atrophin-1 PF03154.15 PVD30750.1 - 2.5 6.3 7.0 3.9 5.6 7.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family Kunitz_BPTI PF00014.23 PVD30751.1 - 6.5e-37 125.5 14.9 2.5e-20 72.5 5.4 2.0 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 PVD30752.1 - 1e-56 189.0 35.3 9.1e-20 70.6 7.6 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Kelch_3 PF13415.6 PVD30752.1 - 0.0056 16.9 8.3 1.4 9.3 0.2 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain EF-hand_6 PF13405.6 PVD30752.1 - 0.032 14.2 0.1 10 6.4 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain Kelch_4 PF13418.6 PVD30752.1 - 0.59 10.2 5.0 20 5.3 0.0 3.5 3 1 0 3 3 3 0 Galactose oxidase, central domain WW PF00397.26 PVD30752.1 - 1.3 9.1 2.7 20 5.4 0.1 2.7 3 0 0 3 3 3 0 WW domain Trypan_PARP PF05887.11 PVD30753.1 - 0.0016 18.4 35.1 0.014 15.3 33.7 2.2 1 1 2 3 3 3 3 Procyclic acidic repetitive protein (PARP) TGF_beta PF00019.20 PVD30756.1 - 9.1e-15 55.5 0.5 2.6e-14 54.1 0.5 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Aldo_ket_red PF00248.21 PVD30758.1 - 1.1e-63 215.1 0.0 1.3e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 PVD30759.1 - 1.3e-42 144.3 12.4 2.4e-16 60.1 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD30759.1 - 4.8e-35 119.5 14.2 4.9e-09 36.6 0.1 7.2 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD30759.1 - 1.5e-31 104.9 13.9 0.00059 20.1 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 PVD30759.1 - 2.9e-31 106.5 12.6 0.00068 20.0 0.0 8.2 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD30759.1 - 1.7e-27 95.1 10.2 6.1e-06 26.4 0.1 7.0 2 1 3 7 7 7 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD30759.1 - 2.5e-08 34.1 0.4 7.2e-08 32.7 0.4 1.8 1 0 0 1 1 1 1 SOCS box CRR7 PF12095.8 PVD30759.1 - 0.5 10.9 1.6 3.1 8.3 0.1 2.9 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 RPN6_N PF18055.1 PVD30760.1 - 5.6e-35 120.2 1.3 5.6e-35 120.2 1.3 2.5 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 PVD30760.1 - 1.4e-18 67.3 0.5 4e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 PVD30760.1 - 1.8e-14 53.2 0.6 4.9e-14 51.7 0.6 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 PVD30760.1 - 0.00029 21.1 8.0 0.00068 19.9 1.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 PVD30760.1 - 0.041 13.6 0.5 0.041 13.6 0.5 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 PVD30760.1 - 0.075 13.2 0.0 40 4.7 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD30760.1 - 0.25 11.9 7.6 0.58 10.7 1.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD30760.1 - 1.7 8.9 3.9 19 5.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SAP PF02037.27 PVD30761.1 - 3.8e-14 52.0 2.1 1.2e-13 50.5 2.1 1.9 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 PVD30761.1 - 3e-07 30.1 18.0 0.00025 20.8 0.1 4.8 4 1 1 5 5 5 4 Tho1/MOS11 C-terminal domain NMT1_3 PF16868.5 PVD30761.1 - 0.012 15.1 1.4 1.3 8.3 0.1 2.2 1 1 1 2 2 2 0 NMT1-like family Telomere_Sde2_2 PF13297.6 PVD30761.1 - 0.018 14.7 0.2 0.018 14.7 0.2 3.1 3 0 0 3 3 3 0 Telomere stability C-terminal PASTA PF03793.19 PVD30761.1 - 0.021 14.7 0.9 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 PASTA domain HeH PF12949.7 PVD30761.1 - 0.026 14.3 0.1 0.089 12.5 0.1 2.0 1 1 0 1 1 1 0 HeH/LEM domain SR-25 PF10500.9 PVD30761.1 - 0.04 13.5 9.0 0.063 12.9 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med24_N PF11277.8 PVD30762.1 - 8.4e-249 828.5 16.6 2.3e-248 827.1 16.6 1.6 1 1 0 1 1 1 1 Mediator complex subunit 24 N-terminal zf-C2H2 PF00096.26 PVD30763.1 - 1.3e-19 69.5 85.7 0.00038 20.8 0.9 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD30763.1 - 1.3e-14 53.6 80.1 0.0006 20.4 0.4 9.5 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD30763.1 - 6.3e-14 51.7 70.8 0.0011 19.3 3.6 10.3 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD30763.1 - 3.7e-07 30.0 6.2 5.5e-05 23.1 0.6 8.9 10 0 0 10 10 10 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD30763.1 - 6.5e-05 22.6 2.5 6.5e-05 22.6 2.5 8.6 9 1 0 9 9 9 3 C2H2-type zinc-finger domain BEX PF04538.12 PVD30763.1 - 0.0092 16.6 4.4 0.03 14.9 4.4 1.9 1 0 0 1 1 1 1 Brain expressed X-linked like family zf-met2 PF12907.7 PVD30763.1 - 0.18 11.9 0.1 0.18 11.9 0.1 4.1 5 0 0 5 5 5 0 Zinc-binding C1_2 PF03107.16 PVD30763.1 - 0.22 11.9 0.1 0.22 11.9 0.1 8.2 5 3 2 7 7 7 0 C1 domain zf-C2H2_jaz PF12171.8 PVD30763.1 - 1.1 9.6 58.9 0.7 10.3 0.2 8.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding TRAF6_Z2 PF18048.1 PVD30763.1 - 3.5 7.8 14.5 6.1 7.0 5.0 3.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 RasGEF PF00617.19 PVD30764.1 - 4e-50 170.5 2.4 2e-48 164.9 0.2 2.4 2 0 0 2 2 2 1 RasGEF domain Ras PF00071.22 PVD30764.1 - 6.7e-40 136.3 0.0 1.2e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Ras family cNMP_binding PF00027.29 PVD30764.1 - 1.4e-33 114.9 0.0 4.8e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Roc PF08477.13 PVD30764.1 - 1e-24 87.1 0.0 2.4e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DEP PF00610.21 PVD30764.1 - 5.1e-21 74.5 2.5 1.5e-20 73.0 1.3 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 PVD30764.1 - 8e-11 42.1 0.6 2.8e-10 40.4 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Arf PF00025.21 PVD30764.1 - 1.4e-08 34.4 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD30764.1 - 0.00014 21.4 0.0 0.00034 20.0 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PVD30764.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cNMP_binding PF00027.29 PVD30765.1 - 3.2e-20 72.0 0.0 2.3e-16 59.6 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain IMUP PF15761.5 PVD30766.1 - 0.58 10.9 6.8 2.4 8.9 1.0 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein PDZ_6 PF17820.1 PVD30767.1 - 0.023 14.5 0.9 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 PDZ domain PDZ_2 PF13180.6 PVD30767.1 - 0.031 14.6 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain GcnA_N PF18229.1 PVD30767.1 - 0.17 12.0 0.4 13 5.9 0.0 2.6 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain AKAP95 PF04988.12 PVD30768.1 - 0.0076 16.5 0.3 0.0076 16.5 0.3 1.4 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) Agouti PF05039.12 PVD30768.1 - 7.8 7.3 10.7 0.77 10.5 1.4 2.1 1 1 1 2 2 2 0 Agouti protein F5_F8_type_C PF00754.25 PVD30769.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.6 1 1 0 1 1 1 1 F5/8 type C domain SUFU_C PF12470.8 PVD30770.1 - 0.037 14.1 0.1 0.039 14.0 0.1 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Agouti PF05039.12 PVD30770.1 - 6.7 7.5 10.2 0.91 10.3 1.2 2.1 1 1 1 2 2 2 0 Agouti protein TRAP-gamma PF07074.12 PVD30770.1 - 7 6.2 6.4 10 5.6 2.8 1.9 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) F5_F8_type_C PF00754.25 PVD30771.1 - 0.00016 21.7 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain EndoU_bacteria PF14436.6 PVD30772.1 - 0.039 14.3 25.8 39 4.6 1.2 5.9 1 1 1 2 2 2 0 Bacterial EndoU nuclease F5_F8_type_C PF00754.25 PVD30773.1 - 1e-08 35.4 0.6 1.1e-05 25.6 0.1 4.5 5 0 0 5 5 5 1 F5/8 type C domain NiFe_hyd_SSU_C PF14720.6 PVD30773.1 - 0.0014 19.0 13.1 3 8.3 0.0 5.3 5 0 0 5 5 5 3 NiFe/NiFeSe hydrogenase small subunit C-terminal zf-HC3 PF16827.5 PVD30773.1 - 5.5 7.3 6.8 5.9 7.2 0.1 3.9 4 0 0 4 4 4 0 zinc-finger F5_F8_type_C PF00754.25 PVD30774.1 - 6.4e-08 32.8 10.2 2.6e-05 24.4 0.0 6.4 6 1 0 6 6 6 2 F5/8 type C domain NiFe_hyd_SSU_C PF14720.6 PVD30774.1 - 0.0006 20.1 4.6 9.9 6.6 0.0 4.3 4 0 0 4 4 4 3 NiFe/NiFeSe hydrogenase small subunit C-terminal Mis12 PF05859.12 PVD30775.1 - 0.0006 19.9 0.9 0.00074 19.6 0.9 1.1 1 0 0 1 1 1 1 Mis12 protein Spt20 PF12090.8 PVD30775.1 - 0.0063 16.2 18.2 0.0063 16.2 18.2 1.0 1 0 0 1 1 1 1 Spt20 family DUF4834 PF16118.5 PVD30775.1 - 0.013 16.4 2.9 0.013 16.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 PVD30775.1 - 0.025 14.4 5.6 0.026 14.3 5.6 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF5421 PF17458.2 PVD30775.1 - 0.083 12.3 8.0 0.077 12.4 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Orf78 PF06024.12 PVD30775.1 - 0.22 11.9 1.9 0.25 11.6 1.9 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TFIIA PF03153.13 PVD30775.1 - 0.28 11.1 17.4 0.27 11.2 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PigN PF04987.14 PVD30775.1 - 0.29 10.0 0.3 0.31 9.8 0.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) EIIBC-GUT_N PF03612.14 PVD30775.1 - 0.44 10.3 4.3 0.46 10.2 4.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med3 PF11593.8 PVD30775.1 - 0.84 8.8 15.0 0.86 8.7 15.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 PVD30775.1 - 2.4 6.8 6.3 2.3 6.9 6.3 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 PVD30775.1 - 5.5 5.8 22.7 6 5.7 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 PVD30775.1 - 6.4 6.5 8.9 3.5 7.4 7.6 1.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Androgen_recep PF02166.16 PVD30775.1 - 8.3 5.1 16.2 7.8 5.2 16.2 1.0 1 0 0 1 1 1 0 Androgen receptor Bindin PF02084.15 PVD30776.1 - 0.54 10.5 2.8 0.7 10.1 2.8 1.1 1 0 0 1 1 1 0 Bindin 7tm_1 PF00001.21 PVD30778.1 - 1.1e-63 215.0 18.9 1.7e-63 214.4 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30778.1 - 1e-09 38.1 20.4 1.5e-09 37.6 20.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Piezo_RRas_bdg PF12166.8 PVD30778.1 - 0.12 11.6 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Spore_III_AB PF09548.10 PVD30778.1 - 0.16 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mtp PF03821.16 PVD30778.1 - 0.71 9.4 7.5 0.085 12.4 2.5 1.8 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter FA_hydroxylase PF04116.13 PVD30778.1 - 2.9 8.3 7.2 0.84 10.0 1.3 2.8 2 1 1 3 3 3 0 Fatty acid hydroxylase superfamily 7tm_1 PF00001.21 PVD30779.1 - 8.3e-54 182.7 27.2 8.3e-54 182.7 27.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD30779.1 - 1.1e-15 57.7 26.3 1.7e-15 57.1 26.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD30779.1 - 9.6e-11 41.8 26.7 1.4e-10 41.3 26.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD30779.1 - 0.031 14.0 18.0 0.048 13.4 18.0 1.4 1 1 0 1 1 1 0 Olfactory receptor DUF2116 PF09889.9 PVD30779.1 - 0.15 12.1 0.3 0.15 12.1 0.3 4.2 4 0 0 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PAM2 PF07145.15 PVD30786.1 - 2.3e-06 26.9 0.3 5e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF4862 PF16154.5 PVD30786.1 - 0.13 11.6 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) 7tm_1 PF00001.21 PVD30787.1 - 3.8e-26 92.0 24.7 1.9e-24 86.4 24.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD30787.1 - 8.9e-10 38.6 12.7 8.9e-10 38.6 12.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD30787.1 - 0.00016 21.2 18.0 0.00019 20.9 18.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD30787.1 - 0.0056 16.5 9.0 0.024 14.4 9.0 2.1 1 1 0 1 1 1 1 Olfactory receptor MORN PF02493.20 PVD30788.1 - 1.1e-18 65.9 19.9 1.7e-05 24.4 0.3 4.8 5 0 0 5 5 5 4 MORN repeat HTH_psq PF05225.16 PVD30789.1 - 1.7e-14 53.3 0.1 1.4e-12 47.1 0.0 2.7 2 0 0 2 2 2 2 helix-turn-helix, Psq domain Cnd2 PF05786.14 PVD30790.1 - 3.2e-133 446.1 16.9 4.2e-133 445.7 16.9 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 PVD30790.1 - 0.00011 22.4 1.7 0.00015 21.9 0.2 2.0 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Mei5 PF10376.9 PVD30791.1 - 2.9e-12 46.9 14.1 9.7e-12 45.2 14.1 2.1 1 1 0 1 1 1 1 Double-strand recombination repair protein Mei5_like PF17021.5 PVD30791.1 - 1.9e-06 27.9 0.5 2.8e-06 27.3 0.5 1.3 1 0 0 1 1 1 1 Putative double-strand recombination repair-like RRM_7 PF16367.5 PVD30793.1 - 1.9e-36 124.1 0.0 1.5e-34 118.0 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 PVD30793.1 - 2.7e-20 72.4 7.4 7.2e-20 71.0 7.4 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 PVD30793.1 - 9.3e-12 44.6 0.0 1.5e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 PVD30793.1 - 0.034 13.9 0.5 0.089 12.6 0.5 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-B_box PF00643.24 PVD30793.1 - 1.8 8.8 7.8 5.4 7.3 7.8 1.8 1 0 0 1 1 1 0 B-box zinc finger RINGv PF12906.7 PVD30796.1 - 6.8e-15 54.9 10.7 6.8e-15 54.9 10.7 1.9 2 0 0 2 2 2 1 RING-variant domain DUF2517 PF10725.9 PVD30796.1 - 0.00079 19.1 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 PVD30796.1 - 0.0034 17.7 6.5 0.0034 17.7 6.5 2.1 2 1 0 2 2 2 1 Ring finger domain zf-CSL PF05207.13 PVD30796.1 - 0.06 13.1 2.0 0.15 11.8 2.0 1.7 1 0 0 1 1 1 0 CSL zinc finger FANCL_C PF11793.8 PVD30796.1 - 0.13 12.5 9.5 0.044 14.0 6.6 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 PVD30796.1 - 0.33 10.8 5.9 1.3 8.8 5.9 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 PVD30796.1 - 0.43 10.5 9.1 1 9.3 9.1 1.7 1 0 0 1 1 1 0 PHD-finger PRIMA1 PF16101.5 PVD30797.1 - 2.8 8.0 8.2 4.4 7.4 8.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MnhB PF04039.13 PVD30798.1 - 0.026 14.8 0.2 0.038 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter Thaumatin PF00314.17 PVD30800.1 - 0.022 14.4 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 Thaumatin family Cep3 PF16846.5 PVD30800.1 - 0.29 9.6 0.0 0.34 9.3 0.0 1.0 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Claudin_2 PF13903.6 PVD30802.1 - 8e-06 25.7 8.5 1.2e-05 25.2 8.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Apt1 PF10351.9 PVD30802.1 - 0.002 17.1 0.1 0.002 17.1 0.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF389 PF04087.14 PVD30802.1 - 0.014 15.5 2.7 0.014 15.5 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF389) DPM3 PF08285.11 PVD30802.1 - 0.055 13.7 0.8 0.13 12.5 0.8 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Got1 PF04178.12 PVD30802.1 - 0.097 13.1 9.3 0.19 12.1 9.3 1.6 1 0 0 1 1 1 0 Got1/Sft2-like family UPF0182 PF03699.13 PVD30802.1 - 0.1 10.7 4.2 0.14 10.2 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DuoxA PF10204.9 PVD30802.1 - 0.24 10.4 10.5 0.054 12.5 7.3 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor DHHC PF01529.20 PVD30802.1 - 0.74 9.9 12.8 2.2 8.4 12.2 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase CDC45 PF02724.14 PVD30802.1 - 1.5 7.0 5.2 2.3 6.4 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Period_C PF12114.8 PVD30802.1 - 2.5 7.6 11.1 3.8 7.0 11.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Med28 PF11594.8 PVD30803.1 - 2.7e-09 37.2 2.5 4.3e-09 36.5 2.5 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 DUF16 PF01519.16 PVD30803.1 - 0.16 12.5 2.8 0.26 11.8 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3824 PF12868.7 PVD30803.1 - 0.64 10.7 16.6 0.97 10.1 16.6 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DHHC PF01529.20 PVD30804.1 - 7.6e-34 116.7 9.6 7.6e-34 116.7 9.6 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Linker_histone PF00538.19 PVD30805.1 - 0.0048 17.2 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family NPR3 PF03666.13 PVD30805.1 - 2.9 6.6 8.1 4.2 6.0 8.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4246 PF14033.6 PVD30806.1 - 0.071 12.2 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) DUF3524 PF12038.8 PVD30807.1 - 3.9e-09 36.6 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Kelch_6 PF13964.6 PVD30808.1 - 4.6e-23 80.7 24.0 1.9e-05 24.7 0.3 7.3 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PVD30808.1 - 8.2e-15 54.1 15.6 0.00037 20.0 0.3 7.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PVD30808.1 - 1.8e-14 53.1 19.1 2.1e-05 24.3 0.1 7.2 6 2 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD30808.1 - 1.8e-14 53.4 22.7 0.005 16.8 0.0 8.0 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD30808.1 - 2.9e-13 49.5 22.9 4.9e-05 23.2 0.3 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PVD30808.1 - 1.2e-07 31.8 26.3 0.038 14.3 0.2 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain PSI PF01437.25 PVD30808.1 - 8.6e-07 29.4 28.1 3.5e-05 24.3 9.4 8.3 8 2 0 8 8 8 5 Plexin repeat Laminin_EGF PF00053.24 PVD30808.1 - 4.4e-05 23.5 42.4 0.00064 19.8 17.3 8.3 6 2 1 9 9 9 2 Laminin EGF domain ER_lumen_recept PF00810.18 PVD30808.1 - 0.25 12.1 2.4 0.55 11.0 2.4 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor T-box PF00907.22 PVD30809.1 - 1e-78 263.8 0.0 5.7e-54 183.2 0.0 2.5 2 0 0 2 2 2 2 T-box PPPI_inhib PF14895.6 PVD30809.1 - 0.086 12.0 2.1 3.7 6.6 0.2 2.2 2 0 0 2 2 2 0 Protein phosphatase 1 inhibitor cNMP_binding PF00027.29 PVD30811.1 - 6.1e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 PVD30812.1 - 8.6e-09 35.4 0.0 3e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain IMS PF00817.20 PVD30812.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family Peptidase_S49_N PF08496.10 PVD30813.1 - 0.18 11.8 1.0 0.28 11.3 0.5 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal CD225 PF04505.12 PVD30814.1 - 0.026 14.6 0.3 0.071 13.3 0.3 1.8 1 1 0 1 1 1 0 Interferon-induced transmembrane protein DUF2721 PF11026.8 PVD30814.1 - 4.1 7.3 7.2 3.1 7.7 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) PAN_1 PF00024.26 PVD30815.1 - 1.6e-09 37.6 3.5 4.9e-09 36.0 1.8 2.6 2 0 0 2 2 2 1 PAN domain Lectin_C PF00059.21 PVD30815.1 - 1.6e-08 35.3 0.1 1.6e-08 35.3 0.1 2.2 3 0 0 3 3 3 1 Lectin C-type domain HisK_sensor PF18698.1 PVD30815.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase sensor domain DUF4430 PF14478.6 PVD30816.1 - 1.8e-08 34.8 0.0 3.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) DUF4430 PF14478.6 PVD30817.1 - 8.9e-09 35.8 0.0 1.3e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Acetyltransf_1 PF00583.25 PVD30817.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4430 PF14478.6 PVD30818.1 - 6.3e-07 29.9 0.0 7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) GCV_H PF01597.19 PVD30819.1 - 1.6e-09 37.7 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein TGF_beta PF00019.20 PVD30820.1 - 1.8e-24 86.7 1.9 3.5e-24 85.8 1.9 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD30820.1 - 1.3e-08 34.9 0.0 3.3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 TGF-beta propeptide DUF4062 PF13271.6 PVD30821.1 - 1.8e-11 44.2 0.0 9.3e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) NACHT PF05729.12 PVD30821.1 - 2.5e-10 40.5 0.0 5.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 PVD30821.1 - 5.7e-08 33.3 0.0 3.6e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain PQQ_2 PF13360.6 PVD30821.1 - 2.5e-06 27.3 0.2 1.6 8.3 0.0 4.7 2 1 1 4 4 4 1 PQQ-like domain WD40 PF00400.32 PVD30821.1 - 4.1e-05 24.3 1.0 0.067 14.1 0.1 4.3 4 0 0 4 4 3 1 WD domain, G-beta repeat ATPase_2 PF01637.18 PVD30821.1 - 0.00023 21.2 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APAF1_C PF17908.1 PVD30821.1 - 0.0012 18.9 0.2 0.0035 17.3 0.2 1.8 1 0 0 1 1 1 1 APAF-1 helical domain AAA PF00004.29 PVD30821.1 - 0.0065 16.9 0.0 0.036 14.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD30821.1 - 0.0067 16.7 0.0 0.029 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF5046 PF16465.5 PVD30821.1 - 0.017 14.6 0.7 2.1 7.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5046) DPPIV_N PF00930.21 PVD30821.1 - 0.13 11.0 0.1 0.64 8.7 0.0 2.2 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mob1_phocein PF03637.17 PVD30822.1 - 4.8e-34 117.8 0.1 6.4e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family An_peroxidase PF03098.15 PVD30823.1 - 6.5e-105 351.7 0.0 7.4e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase ExoD PF06055.12 PVD30823.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD 7tm_1 PF00001.21 PVD30826.1 - 1.1e-15 57.7 19.2 1.4e-15 57.3 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD30826.1 - 1.1e-06 28.2 12.8 7.8e-06 25.4 0.5 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD30826.1 - 0.0055 16.4 24.0 0.086 12.4 22.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Phage_holin_3_6 PF07332.11 PVD30826.1 - 0.013 15.5 0.5 0.013 15.5 0.5 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM154 PF15102.6 PVD30826.1 - 0.033 14.1 0.1 0.096 12.6 0.0 1.8 1 1 0 1 1 1 0 TMEM154 protein family PRIMA1 PF16101.5 PVD30826.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 7tm_2 PF00002.24 PVD30827.1 - 1.8e-56 191.2 17.8 2.9e-56 190.5 17.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30827.1 - 2.1e-12 47.1 3.1 4.7e-12 46.0 3.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain Alba PF01918.21 PVD30828.1 - 3.4e-17 62.0 0.4 5.5e-17 61.3 0.4 1.4 1 0 0 1 1 1 1 Alba Neur_chan_memb PF02932.16 PVD30828.1 - 0.27 11.3 3.6 0.32 11.0 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.19 PVD30828.1 - 3.3 6.5 6.9 4.8 6.0 6.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Bcl-2 PF00452.19 PVD30829.1 - 7.2e-30 103.6 0.1 1.1e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 PVD30829.1 - 5.8e-05 22.8 0.9 8.3e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 PVD30829.1 - 0.053 14.2 0.0 0.08 13.6 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like HSP70 PF00012.20 PVD30831.1 - 3e-106 356.0 0.3 1e-83 281.6 0.2 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 PVD30831.1 - 1.7e-17 63.2 0.3 3.4e-17 62.3 0.3 1.5 1 1 0 1 1 1 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 PVD30831.1 - 0.00075 19.1 0.6 0.49 9.8 0.0 2.9 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 PVD30831.1 - 0.00094 18.5 0.1 0.0038 16.5 0.0 2.0 2 1 0 2 2 2 1 StbA protein FtsA PF14450.6 PVD30831.1 - 0.0028 18.0 0.1 0.33 11.4 0.0 2.9 2 1 0 2 2 2 1 Cell division protein FtsA DDR PF08841.10 PVD30831.1 - 0.029 13.4 0.2 0.69 8.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Raco_middle PF17651.1 PVD30831.1 - 0.06 13.0 0.3 17 5.1 0.0 2.8 3 0 0 3 3 3 0 RACo middle region TROVE PF05731.11 PVD30832.1 - 1.2e-48 166.3 1.0 3.8e-46 158.1 1.0 2.4 1 1 0 1 1 1 1 TROVE domain MRP-63 PF14978.6 PVD30832.1 - 2.1 9.0 5.3 0.36 11.5 1.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 TROVE PF05731.11 PVD30833.1 - 1.4e-54 185.9 1.8 6.9e-51 173.7 0.3 2.5 2 1 1 3 3 3 2 TROVE domain TROVE PF05731.11 PVD30834.1 - 1.4e-45 156.2 0.0 3.7e-43 148.2 0.0 2.3 1 1 0 1 1 1 1 TROVE domain DUF808 PF05661.12 PVD30834.1 - 0.15 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Nucleoside_tran PF01733.18 PVD30835.1 - 2.1e-71 240.8 15.3 2.1e-71 240.8 15.3 2.1 2 1 0 2 2 2 1 Nucleoside transporter DUF3439 PF11921.8 PVD30837.1 - 0.11 12.5 7.4 0.11 12.5 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Hexokinase_2 PF03727.16 PVD30838.1 - 7.6e-86 287.4 0.0 1.1e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 PVD30838.1 - 2.4e-71 239.8 0.0 3.4e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase AAA_lid_3 PF17862.1 PVD30838.1 - 0.12 12.2 0.2 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA+ lid domain cobW PF02492.19 PVD30838.1 - 0.16 11.5 1.2 0.34 10.5 1.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Hexokinase_2 PF03727.16 PVD30839.1 - 2.4e-82 276.0 0.0 3.4e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 PVD30839.1 - 3.2e-33 115.3 0.8 9e-28 97.5 0.0 2.3 1 1 1 2 2 2 2 Hexokinase PGM_PMM_III PF02880.16 PVD30839.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ACBP PF00887.19 PVD30841.1 - 3.9e-29 100.7 2.0 5.7e-29 100.2 2.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Sulfotransfer_1 PF00685.27 PVD30842.1 - 1e-05 25.2 0.6 3.2e-05 23.6 0.3 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD30842.1 - 5.5e-05 23.6 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family CoA_transf_3 PF02515.17 PVD30843.1 - 1.2e-125 419.5 0.0 1.3e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 PVD30843.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PLAC8 PF04749.17 PVD30844.1 - 5.2e-20 72.3 6.3 6.6e-20 72.0 6.3 1.1 1 0 0 1 1 1 1 PLAC8 family Kelch_1 PF01344.25 PVD30845.1 - 3.5e-28 96.9 3.2 1.3e-06 27.8 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD30845.1 - 2.7e-22 78.5 1.4 0.00017 21.5 0.1 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD30845.1 - 6.5e-22 77.0 3.6 6.9e-05 23.0 0.0 5.1 3 1 1 4 4 4 4 Kelch motif Kelch_3 PF13415.6 PVD30845.1 - 3.1e-17 62.4 0.5 0.0022 18.3 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD30845.1 - 9.6e-16 57.4 3.2 0.00032 20.6 0.2 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 PVD30845.1 - 5.4e-10 38.8 13.2 0.056 13.4 0.5 5.8 5 1 0 5 5 5 4 Kelch motif Clathrin PF00637.20 PVD30846.1 - 6.7e-21 74.7 0.3 6.7e-21 74.7 0.3 3.0 3 1 1 4 4 4 1 Region in Clathrin and VPS Vps39_2 PF10367.9 PVD30846.1 - 1.7e-05 25.2 0.1 4.6e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 ANAPC4_WD40 PF12894.7 PVD30846.1 - 0.0024 18.1 0.7 1.8 8.9 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 PVD30846.1 - 0.0037 17.3 0.3 0.0037 17.3 0.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD30846.1 - 0.01 16.1 0.4 0.01 16.1 0.4 2.3 3 0 0 3 3 2 0 Ring finger domain WD40 PF00400.32 PVD30846.1 - 0.015 16.1 0.0 0.056 14.3 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_11 PF17123.5 PVD30846.1 - 0.02 14.6 0.9 0.02 14.6 0.9 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 PVD30846.1 - 0.067 13.1 1.9 0.2 11.5 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.6 PVD30846.1 - 0.15 12.2 0.2 47 4.3 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 PVD30846.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.8 3 0 0 3 3 2 0 Zinc-finger zf-RING_5 PF14634.6 PVD30846.1 - 0.25 11.3 4.6 0.74 9.8 2.1 2.8 2 1 1 3 3 3 0 zinc-RING finger domain TPR_1 PF00515.28 PVD30846.1 - 0.5 10.3 4.9 3 7.8 0.9 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD30846.1 - 0.71 10.1 3.5 5.5 7.4 1.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD30846.1 - 0.84 10.0 5.5 10 6.5 0.7 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 PVD30846.1 - 2.5 8.0 8.5 0.7 9.8 3.2 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD30846.1 - 4.1 7.8 5.4 10 6.5 3.3 2.6 2 1 1 3 3 3 0 RING-H2 zinc finger domain Pou PF00157.17 PVD30847.1 - 1.1e-29 102.2 0.1 2.5e-29 101.0 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 PVD30847.1 - 9.1e-17 60.7 1.0 3.4e-16 58.8 1.0 2.0 1 0 0 1 1 1 1 Homeodomain HOCHOB PF17943.1 PVD30847.1 - 0.0041 17.8 0.1 0.0075 17.0 0.1 1.4 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox HTH_31 PF13560.6 PVD30847.1 - 0.0073 16.6 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 PVD30847.1 - 0.12 12.4 0.1 29 4.8 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix Homeobox_KN PF05920.11 PVD30847.1 - 0.16 11.9 0.0 0.49 10.3 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain HECT PF00632.25 PVD30848.1 - 1.1e-100 337.1 0.0 1.5e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 PVD30848.1 - 1.6e-34 118.3 1.0 3e-34 117.4 1.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 PVD30848.1 - 7.9e-32 109.2 1.7 1.1e-28 99.1 0.4 2.5 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 PVD30848.1 - 6e-18 64.6 0.0 2.3e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.30 PVD30848.1 - 2.2e-09 37.5 0.0 5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 PVD30849.1 - 1.3e-19 70.5 0.4 2e-13 50.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD30849.1 - 3.1e-19 68.5 2.2 3.4e-05 24.1 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PVD30849.1 - 3.4e-19 68.6 5.3 5.8e-08 32.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD30849.1 - 1e-16 59.3 0.3 6.6e-05 23.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PVD30849.1 - 2.6e-16 59.8 0.3 6.7e-11 42.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) BRCT PF00533.26 PVD30849.1 - 4.8e-10 39.7 0.1 3.1e-07 30.7 0.0 3.2 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD30849.1 - 5.1e-08 33.2 0.0 0.0045 17.4 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain zf-RING_6 PF14835.6 PVD30849.1 - 6.4e-06 25.9 2.7 6.4e-06 25.9 2.7 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein RTT107_BRCT_5 PF16770.5 PVD30849.1 - 0.018 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 PVD30849.1 - 0.12 12.3 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain WD40 PF00400.32 PVD30850.1 - 9.5e-25 86.4 21.7 0.0063 17.3 0.1 10.8 11 0 0 11 11 11 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 PVD30850.1 - 0.0013 17.6 0.1 0.0041 15.9 0.0 1.9 3 0 0 3 3 3 1 Nup133 N terminal like DOMON PF03351.17 PVD30851.1 - 3.2e-15 56.5 0.7 7e-14 52.1 0.0 2.6 2 1 0 2 2 2 1 DOMON domain Mucin2_WxxW PF13330.6 PVD30852.1 - 1.8e-124 406.9 80.4 1.9e-17 63.8 0.1 10.1 10 0 0 10 10 10 8 Mucin-2 protein WxxW repeating region F5_F8_type_C PF00754.25 PVD30852.1 - 2e-27 95.8 0.0 2e-27 95.8 0.0 2.7 4 0 0 4 4 4 1 F5/8 type C domain Ldl_recept_a PF00057.18 PVD30852.1 - 1e-05 25.6 8.4 1e-05 25.6 8.4 8.1 8 0 0 8 8 8 1 Low-density lipoprotein receptor domain class A TIL PF01826.17 PVD30852.1 - 3.7e-05 23.9 13.4 3.7e-05 23.9 13.4 13.2 14 2 0 14 14 14 1 Trypsin Inhibitor like cysteine rich domain TTSSLRR PF12468.8 PVD30852.1 - 3.2 8.1 14.0 3.8 7.8 0.2 6.0 6 0 0 6 6 6 0 Type III secretion system leucine rich repeat protein Mucin2_WxxW PF13330.6 PVD30853.1 - 3.8e-34 117.4 18.7 2e-15 57.3 4.8 3.2 3 0 0 3 3 3 3 Mucin-2 protein WxxW repeating region NHL PF01436.21 PVD30853.1 - 0.002 18.1 0.9 7.3 6.8 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Ntox50 PF15542.6 PVD30853.1 - 0.071 13.9 0.0 24 5.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial toxin 50 Mucin2_WxxW PF13330.6 PVD30854.1 - 2.4e-85 281.5 62.6 1.1e-14 55.0 4.2 6.3 6 0 0 6 6 6 6 Mucin-2 protein WxxW repeating region F5_F8_type_C PF00754.25 PVD30854.1 - 3.7e-59 198.4 1.9 1.3e-21 77.0 0.1 3.7 2 1 1 3 3 3 3 F5/8 type C domain Ntox50 PF15542.6 PVD30854.1 - 0.00093 20.0 0.0 1.4e+02 3.3 0.0 4.8 5 0 0 5 5 5 0 Bacterial toxin 50 IL13 PF03487.13 PVD30854.1 - 0.0095 15.7 5.4 21 4.9 0.1 4.4 4 0 0 4 4 4 1 Interleukin-13 BsuBI_PstI_RE_N PF17728.1 PVD30854.1 - 0.026 14.4 0.0 1.8e+02 2.0 0.0 4.1 4 0 0 4 4 4 0 BsuBI/PstI restriction endonuclease HTH domain F5_F8_type_C PF00754.25 PVD30855.1 - 1.3e-19 70.5 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain OMP_b-brl_2 PF13568.6 PVD30855.1 - 0.00038 20.5 0.0 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain F5_F8_type_C PF00754.25 PVD30857.1 - 2.9e-35 121.2 7.7 1.4e-14 54.3 0.1 3.3 3 0 0 3 3 3 3 F5/8 type C domain F5_F8_type_C PF00754.25 PVD30858.1 - 1.4e-24 86.7 0.1 3.1e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain Mucin2_WxxW PF13330.6 PVD30858.1 - 5.6e-21 75.2 0.1 1.3e-20 74.0 0.1 1.6 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region TPP_enzyme_M PF00205.22 PVD30858.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Mucin2_WxxW PF13330.6 PVD30859.1 - 2.4e-15 57.1 0.3 2.9e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region VWD PF00094.25 PVD30860.1 - 4.8e-44 150.4 13.4 9.7e-30 103.9 0.7 3.6 2 1 1 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 PVD30860.1 - 6.2e-32 109.8 44.2 4.9e-16 58.9 10.1 8.4 8 0 0 8 8 8 3 C8 domain Mucin2_WxxW PF13330.6 PVD30860.1 - 3.1e-30 104.8 12.4 1.6e-19 70.5 3.7 6.9 8 1 0 8 8 8 2 Mucin-2 protein WxxW repeating region TIL PF01826.17 PVD30860.1 - 6.7e-28 96.7 95.6 8.2e-13 48.4 19.3 12.3 11 2 0 11 11 11 4 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 PVD30860.1 - 3.4e-06 27.3 22.9 8.5e-06 26.0 7.2 13.3 8 4 4 12 12 12 4 von Willebrand factor type C domain DUF1521 PF07481.11 PVD30860.1 - 0.0073 16.3 0.2 0.02 14.9 0.2 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1521) RhoGAP PF00620.27 PVD30862.1 - 6.1e-38 130.0 0.0 1.3e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 PVD30862.1 - 1.3e-08 34.6 3.2 1.3e-08 34.6 3.2 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Dynamitin PF04912.14 PVD30862.1 - 0.00032 20.1 4.3 0.00049 19.5 4.3 1.2 1 0 0 1 1 1 1 Dynamitin Ax_dynein_light PF10211.9 PVD30862.1 - 0.12 12.3 9.9 0.23 11.4 9.9 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain GAGBD PF16828.5 PVD30862.1 - 0.21 11.7 3.5 0.39 10.8 3.5 1.4 1 0 0 1 1 1 0 GAG-binding domain on surface antigen EAP30 PF04157.16 PVD30864.1 - 8e-66 221.7 0.6 1.5e-65 220.8 0.0 1.6 2 0 0 2 2 2 1 EAP30/Vps36 family SH3_2 PF07653.17 PVD30866.1 - 0.16 11.6 0.4 0.31 10.8 0.4 1.5 1 0 0 1 1 1 0 Variant SH3 domain Asn_synthase PF00733.21 PVD30867.1 - 3.3e-84 283.6 0.6 9.8e-51 173.5 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PVD30867.1 - 2.5e-26 92.0 0.0 5.4e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PVD30867.1 - 3.2e-20 72.7 0.0 6.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 PVD30867.1 - 6.1e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 PVD30867.1 - 0.0043 15.9 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 PVD30867.1 - 0.0095 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 PVD30867.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Rox3 PF08633.10 PVD30868.1 - 0.32 11.3 2.4 1.3 9.3 2.1 1.9 1 1 1 2 2 2 0 Rox3 mediator complex subunit MFS_1 PF07690.16 PVD30869.1 - 3.5e-11 42.6 62.2 1.4e-07 30.8 33.5 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily 7TM_GPCR_Srab PF10292.9 PVD30869.1 - 0.036 13.0 3.4 0.93 8.4 0.0 3.4 3 0 0 3 3 3 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Tom6 PF17112.5 PVD30869.1 - 2.9 7.5 5.9 16 5.1 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom6, fungal DUF1072 PF06380.11 PVD30869.1 - 4.2 7.3 7.4 31 4.5 0.8 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) MtN3_slv PF03083.16 PVD30869.1 - 6.5 6.9 15.2 1.1 9.3 2.8 4.1 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Proteasome PF00227.26 PVD30870.1 - 3.6e-44 150.5 0.0 4.1e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SQHop_cyclase_C PF13243.6 PVD30871.1 - 4.1e-57 193.7 0.0 5.4e-51 173.6 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 PVD30871.1 - 6.8e-49 166.5 0.0 3.6e-42 144.5 0.0 4.4 4 1 1 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 PVD30871.1 - 8.7e-40 134.2 9.1 2.2e-11 43.3 0.0 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 PVD30871.1 - 0.00027 20.1 0.0 0.17 10.9 0.1 3.1 2 1 1 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 PVD30871.1 - 0.0014 18.0 0.0 7 5.9 0.0 3.8 2 1 1 3 3 3 2 Pectic acid lyase Histone PF00125.24 PVD30872.1 - 6.5e-20 71.8 0.1 7.2e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PVD30872.1 - 5.5e-07 29.8 0.1 8.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PVD30872.1 - 0.00063 20.2 0.0 0.00091 19.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-T_C PF15511.6 PVD30872.1 - 0.023 14.8 0.1 0.038 14.1 0.1 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 PVD30872.1 - 0.035 14.3 0.1 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) ANAPC4_WD40 PF12894.7 PVD30873.1 - 2.3e-29 101.5 0.1 2.1e-05 24.8 0.0 6.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD30873.1 - 5.4e-25 87.2 18.5 1.3e-06 29.0 0.8 7.1 6 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 PVD30873.1 - 4.1e-12 46.4 0.0 4.5e-07 29.9 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PVD30873.1 - 9.9e-07 28.5 0.1 0.00044 20.1 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 PVD30873.1 - 2.3e-05 22.7 0.1 0.0021 16.1 0.0 2.3 1 1 1 2 2 2 2 IKI3 family Coatomer_WDAD PF04053.14 PVD30873.1 - 0.0001 21.5 0.0 0.3 10.1 0.0 3.1 2 1 1 3 3 3 2 Coatomer WD associated region Ge1_WD40 PF16529.5 PVD30873.1 - 0.0004 19.5 0.6 4.2 6.2 0.0 4.0 2 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PVD30873.1 - 0.00089 17.9 0.0 0.096 11.2 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 PVD30873.1 - 0.0023 16.6 0.2 0.0058 15.3 0.1 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 PVD30873.1 - 0.0053 15.6 0.4 4.6 5.9 0.1 2.9 2 1 0 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DPPIV_N PF00930.21 PVD30873.1 - 0.022 13.5 0.0 1 8.1 0.0 2.5 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phage_tail_X PF05489.12 PVD30873.1 - 0.04 13.6 0.3 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Protein X VID27 PF08553.10 PVD30873.1 - 0.056 12.5 0.0 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 PVD30873.1 - 0.094 12.0 0.0 5.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ank_2 PF12796.7 PVD30874.1 - 4.4e-22 78.5 0.4 1.5e-11 44.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD30874.1 - 2.8e-20 70.3 0.8 0.004 17.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PVD30874.1 - 9.7e-19 67.5 6.7 1.7e-05 25.3 0.6 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD30874.1 - 1.9e-14 53.5 1.0 2.5e-06 27.6 0.2 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD30874.1 - 2.5e-14 52.9 0.6 0.0015 18.9 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat fn3 PF00041.21 PVD30874.1 - 1.2e-05 25.5 0.2 3.8e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD30874.1 - 0.0028 18.2 0.1 0.007 16.9 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD30874.1 - 0.011 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Glyco_transf_7C PF02709.14 PVD30875.1 - 4.9e-27 93.4 0.2 1.1e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 PVD30875.1 - 5.5e-22 77.8 0.0 7.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 PVD30875.1 - 0.021 14.3 0.1 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 CHGN PF05679.16 PVD30875.1 - 0.057 12.2 0.1 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase Clr2_transil PF16761.5 PVD30875.1 - 0.14 13.0 1.5 1.6 9.6 0.0 2.5 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 UQ_con PF00179.26 PVD30876.1 - 7.1e-13 48.4 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NUC173 PF08161.12 PVD30877.1 - 8.8e-65 218.2 12.6 5.9e-64 215.5 0.2 4.8 4 1 2 6 6 6 2 NUC173 domain Katanin_con80 PF13925.6 PVD30877.1 - 5e-05 23.4 1.2 0.00035 20.7 0.4 2.7 2 0 0 2 2 2 1 con80 domain of Katanin V-ATPase_H_N PF03224.14 PVD30877.1 - 0.34 10.2 10.6 1.3 8.3 1.3 4.0 3 1 1 4 4 4 0 V-ATPase subunit H DUF4042 PF13251.6 PVD30877.1 - 0.47 10.1 4.2 20 4.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) HEAT PF02985.22 PVD30877.1 - 1.2 9.6 3.8 4 8.0 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.8 PVD30877.1 - 1.3 8.6 13.3 0.097 12.2 1.5 4.0 4 0 0 4 4 4 0 CLASP N terminal Mitofilin PF09731.9 PVD30878.1 - 2.1e-139 466.2 24.0 2.6e-139 465.9 24.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein MADF_DNA_bdg PF10545.9 PVD30878.1 - 0.0047 17.2 1.9 0.0047 17.2 1.9 3.7 1 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like FAT PF02259.23 PVD30879.1 - 4.9e-61 206.9 8.4 4.9e-61 206.9 8.4 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 PVD30879.1 - 3.7e-14 53.2 0.0 1.3e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PVD30879.1 - 3.2e-06 26.9 0.1 1.1e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 FATC domain ACDC PF14733.6 PVD30879.1 - 0.016 15.5 0.2 0.14 12.5 0.2 2.7 1 0 0 1 1 1 0 AP2-coincident C-terminal DUF717 PF05338.12 PVD30879.1 - 0.099 12.8 1.0 1.7 8.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF717) 7tm_2 PF00002.24 PVD30882.1 - 1.4e-46 158.8 8.8 1.8e-46 158.4 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30883.1 - 4e-08 33.4 3.3 4e-08 33.4 3.3 1.8 2 1 0 2 2 2 1 Hormone receptor domain 7tm_1 PF00001.21 PVD30885.1 - 4.4e-54 183.6 24.1 5.4e-54 183.3 24.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD30885.1 - 1.7e-09 37.5 16.0 2.3e-09 37.1 16.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 PVD30885.1 - 0.001 18.7 21.7 0.0035 17.0 20.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD30885.1 - 0.0078 16.0 16.5 0.013 15.3 16.5 1.5 1 1 0 1 1 1 1 Olfactory receptor Herpes_US9 PF06072.11 PVD30885.1 - 0.48 10.3 3.0 4.6 7.2 0.5 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Nucleos_tra2_C PF07662.13 PVD30886.1 - 8.3e-38 130.3 2.3 2.2e-34 119.1 1.5 2.5 2 0 0 2 2 2 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD30886.1 - 5.6e-24 84.5 1.0 2.5e-23 82.5 1.0 2.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus F5_F8_type_C PF00754.25 PVD30887.1 - 6.9e-12 45.6 0.1 6.5e-09 36.0 0.0 3.5 3 0 0 3 3 3 2 F5/8 type C domain Phenol_hyd_sub PF06099.11 PVD30887.1 - 0.062 13.3 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Phenol hydroxylase subunit PARM PF17061.5 PVD30887.1 - 1.9 8.6 20.4 0.57 10.3 4.2 2.3 2 0 0 2 2 2 0 PARM Tetraspanin PF00335.20 PVD30888.1 - 4.1e-12 46.3 0.6 6.6e-12 45.6 0.6 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4514 PF14986.6 PVD30888.1 - 2.1 8.4 4.1 0.56 10.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) 7tm_1 PF00001.21 PVD30889.1 - 5.3e-10 39.1 10.1 5.8e-10 38.9 6.6 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD30889.1 - 5.7e-06 26.1 5.3 6.7e-06 25.9 5.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD30889.1 - 0.00022 20.7 7.1 0.0003 20.2 7.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD30890.1 - 2.2e-36 125.5 27.9 8.4e-19 67.9 11.9 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD30890.1 - 1.3e-09 38.1 33.0 9.4e-05 22.2 12.1 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD30890.1 - 3.6e-08 33.1 34.0 7.4e-05 22.3 13.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx LAB_N PF07578.11 PVD30890.1 - 0.01 15.9 1.7 0.62 10.2 0.2 3.0 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain HECT_2 PF09814.9 PVD30892.1 - 2.8e-41 141.6 9.6 3.3e-40 138.1 9.6 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Vault PF01505.18 PVD30897.1 - 2.7e-47 158.6 2.1 9.4e-13 48.1 0.0 4.7 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 PVD30897.1 - 5.8e-46 155.3 0.4 1.1e-45 154.5 0.4 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 PVD30897.1 - 4.1e-31 106.8 0.1 7.7e-28 96.3 0.1 2.5 2 0 0 2 2 2 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 PVD30897.1 - 5.2e-23 80.9 0.7 3.6e-22 78.2 0.1 2.5 2 0 0 2 2 2 1 Major Vault Protein repeat domain Vault_2 PF17794.1 PVD30897.1 - 6.9e-12 45.6 0.1 5.5e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain DUF3196 PF11428.8 PVD30897.1 - 0.028 14.0 0.2 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) DUF3601 PF12208.8 PVD30897.1 - 0.034 14.2 0.0 51 4.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) EGF_3 PF12947.7 PVD30900.1 - 0.02 15.1 6.0 0.02 15.1 6.0 2.0 2 1 0 2 2 2 0 EGF domain EB PF01683.18 PVD30900.1 - 0.22 11.8 7.7 0.43 10.9 7.7 1.5 1 0 0 1 1 1 0 EB module hEGF PF12661.7 PVD30900.1 - 2 9.2 8.2 1.3 9.8 5.6 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.15 PVD30900.1 - 9.8 6.5 10.1 32 4.8 10.1 1.9 1 1 0 1 1 1 0 Calcium-binding EGF domain 7tm_1 PF00001.21 PVD30904.1 - 6.6e-37 127.3 16.3 8.5e-37 126.9 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD30904.1 - 0.13 11.5 15.1 1.7 7.8 15.1 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD30904.1 - 0.82 9.2 16.1 0.045 13.4 10.3 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx MMADHC PF10229.9 PVD30905.1 - 6e-37 127.9 0.2 1.6e-26 93.7 0.0 2.0 1 1 1 2 2 2 2 Methylmalonic aciduria and homocystinuria type D protein adh_short PF00106.25 PVD30907.1 - 8.8e-24 84.0 0.1 1.7e-23 83.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD30907.1 - 8.4e-11 41.9 0.1 2.7e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD30907.1 - 0.029 14.3 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 KR domain CX PF01705.19 PVD30907.1 - 0.18 12.4 0.0 35 5.1 0.0 2.4 2 0 0 2 2 2 0 CX module Glyco_hydro_35 PF01301.19 PVD30908.1 - 9.9e-55 186.4 0.0 1.2e-54 186.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 PVD30908.1 - 4.5e-06 27.2 0.3 6.4e-05 23.5 0.0 2.7 3 1 1 4 4 4 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 PVD30908.1 - 0.064 12.6 0.1 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_35 PF01301.19 PVD30909.1 - 5.5e-112 374.5 0.1 7e-112 374.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 PVD30909.1 - 4.8e-10 39.3 0.3 2e-09 37.3 0.3 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 PVD30909.1 - 0.0003 21.3 0.6 0.0016 19.0 0.0 2.5 3 1 0 3 3 3 1 Beta-galactosidase jelly roll domain CLAMP PF14769.6 PVD30910.1 - 2.6e-23 82.3 0.4 7.2e-23 80.9 0.4 1.8 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF2097 PF09870.9 PVD30910.1 - 0.02 15.1 2.9 5.1 7.4 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) FDX-ACB PF03147.14 PVD30910.1 - 0.055 13.9 1.8 0.89 10.0 0.1 3.0 2 2 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Cactin_mid PF10312.9 PVD30910.1 - 0.51 10.0 10.0 2.8 7.6 2.2 2.3 2 0 0 2 2 2 0 Conserved mid region of cactin DJ-1_PfpI PF01965.24 PVD30911.1 - 3.5e-06 26.9 0.0 1.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Acyl-CoA_dh_1 PF00441.24 PVD30912.1 - 3.4e-37 127.9 0.2 6e-37 127.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD30912.1 - 1.8e-25 89.8 0.0 4.1e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD30912.1 - 2.1e-23 82.3 0.0 3.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD30912.1 - 1.6e-21 76.9 0.0 3.1e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2652 PF10851.8 PVD30912.1 - 0.028 14.6 0.2 0.071 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) HpaB_N PF11794.8 PVD30912.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal YtzH PF14165.6 PVD30912.1 - 0.15 12.5 1.2 1.9 8.9 0.1 2.6 2 0 0 2 2 2 0 YtzH-like protein K_oxygenase PF13434.6 PVD30913.1 - 0.044 12.9 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-H2C2_5 PF13909.6 PVD30915.1 - 0.00028 20.6 1.5 0.045 13.5 0.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD30915.1 - 1.2 10.2 42.7 0.6 11.1 4.9 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD30915.1 - 3.7 7.9 17.7 0.23 11.8 7.8 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 PVD30915.1 - 6.1 7.4 14.5 0.35 11.3 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PVD30916.1 - 1.2 10.1 9.7 0.22 12.4 2.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Rab15_effector PF15208.6 PVD30917.1 - 0.25 10.6 2.3 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Rab15 effector Aldo_ket_red PF00248.21 PVD30917.1 - 0.38 9.9 4.6 2.8 7.1 4.6 2.2 1 1 0 1 1 1 0 Aldo/keto reductase family DUF2052 PF09747.9 PVD30918.1 - 0.0037 17.4 11.9 0.0038 17.4 11.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 PVD30918.1 - 0.019 14.8 5.5 0.016 15.0 5.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Serinc PF03348.15 PVD30918.1 - 0.02 13.9 4.6 0.022 13.7 4.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paf1 PF03985.13 PVD30918.1 - 0.036 13.1 15.6 0.038 13.0 15.6 1.0 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 PVD30918.1 - 0.061 13.0 10.3 0.068 12.8 10.3 1.1 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 PVD30918.1 - 0.067 12.9 3.7 0.059 13.1 3.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Nucleoside_tran PF01733.18 PVD30918.1 - 0.072 12.5 4.1 0.085 12.2 4.1 1.0 1 0 0 1 1 1 0 Nucleoside transporter RR_TM4-6 PF06459.12 PVD30918.1 - 0.11 12.4 9.1 0.1 12.4 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 PVD30918.1 - 0.11 12.8 1.9 0.12 12.6 1.9 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) CPSF100_C PF13299.6 PVD30918.1 - 0.12 12.6 7.1 0.12 12.5 7.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GOLD_2 PF13897.6 PVD30918.1 - 0.21 12.1 3.9 0.24 11.9 3.9 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DDHD PF02862.17 PVD30918.1 - 0.23 11.6 3.7 0.21 11.7 3.7 1.1 1 0 0 1 1 1 0 DDHD domain CTU2 PF10288.9 PVD30918.1 - 0.32 11.3 7.1 0.37 11.0 7.1 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Connexin PF00029.19 PVD30918.1 - 0.38 10.5 7.2 0.43 10.3 7.2 1.1 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 PVD30918.1 - 0.4 10.4 6.9 0.42 10.3 6.9 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CLN3 PF02487.17 PVD30918.1 - 0.49 9.4 5.2 0.53 9.3 5.2 1.0 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 PVD30918.1 - 0.54 9.7 10.8 0.58 9.6 10.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ctr PF04145.15 PVD30918.1 - 0.56 10.8 1.5 0.62 10.7 1.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Sporozoite_P67 PF05642.11 PVD30918.1 - 0.57 8.2 5.3 0.62 8.1 5.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 PVD30918.1 - 0.58 8.4 11.1 0.6 8.3 11.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 PVD30918.1 - 0.65 8.9 5.9 0.6 9.0 5.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 PVD30918.1 - 0.68 9.1 7.0 0.72 9.0 7.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 PVD30918.1 - 0.88 8.3 8.4 0.81 8.4 8.4 1.0 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 PVD30918.1 - 0.98 7.8 2.5 1 7.7 2.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FPN1 PF06963.12 PVD30918.1 - 1.2 7.6 2.4 1.2 7.6 2.4 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Spt20 PF12090.8 PVD30918.1 - 2 8.0 15.3 2.4 7.7 15.3 1.2 1 0 0 1 1 1 0 Spt20 family Folate_carrier PF01770.18 PVD30918.1 - 2.1 7.0 4.7 2.5 6.8 4.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 PVD30918.1 - 2.6 5.9 8.5 2.6 5.8 8.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Roughex PF06020.11 PVD30918.1 - 2.7 7.0 13.0 2.7 7.0 13.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PigN PF04987.14 PVD30918.1 - 3 6.6 3.8 3.3 6.5 3.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Cnd2 PF05786.14 PVD30918.1 - 3 6.4 14.2 3.4 6.2 14.2 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 AIF_C PF14721.6 PVD30918.1 - 3.2 8.1 7.5 3.7 7.9 7.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.12 PVD30918.1 - 3.6 6.9 18.6 3.9 6.8 18.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PTPRCAP PF15713.5 PVD30918.1 - 3.7 7.8 16.9 4.2 7.7 16.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ferlin_C PF16165.5 PVD30918.1 - 4.3 7.3 6.1 4.7 7.1 6.1 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Zip PF02535.22 PVD30918.1 - 7.9 5.6 5.5 8.8 5.4 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.8 PVD30918.1 - 8.8 6.1 7.7 10 5.8 7.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3682 PF12446.8 PVD30918.1 - 10 6.6 29.2 15 6.1 29.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) 7tm_2 PF00002.24 PVD30919.1 - 3.4e-24 85.5 3.0 8e-19 67.9 0.4 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) Gp-FAR-1 PF05823.12 PVD30920.1 - 0.027 14.8 0.4 0.042 14.2 0.1 1.5 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Planc_extracel PF07595.12 PVD30921.1 - 0.37 10.7 2.5 4.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Planctomycete extracellular COE1_DBD PF16422.5 PVD30923.1 - 4.6e-123 409.1 1.2 6.2e-123 408.7 1.2 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 PVD30923.1 - 1e-30 105.2 0.6 1.9e-30 104.3 0.6 1.5 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 PVD30923.1 - 6.1e-13 48.7 0.3 1.2e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 IPT/TIG domain Trypsin PF00089.26 PVD30924.1 - 5.9e-36 124.4 0.0 9.3e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD30924.1 - 0.0026 18.7 0.0 0.0043 17.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain SEA PF01390.20 PVD30924.1 - 0.019 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 SEA domain DUF1986 PF09342.11 PVD30924.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 PVD30925.1 - 6.4e-47 160.2 0.0 8.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD30925.1 - 0.0076 17.2 0.2 0.03 15.2 0.2 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Eclosion PF04736.12 PVD30925.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Eclosion hormone SEA PF01390.20 PVD30926.1 - 0.091 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 SEA domain Trypsin PF00089.26 PVD30928.1 - 5.2e-25 88.6 0.0 3.4e-24 85.9 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD30928.1 - 0.011 16.6 0.0 0.025 15.5 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Glycophorin_A PF01102.18 PVD30929.1 - 4 7.7 5.7 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Glycophorin A DDHD PF02862.17 PVD30931.1 - 2.9e-47 161.7 0.4 7.7e-47 160.3 0.0 1.8 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 PVD30931.1 - 2.1e-08 34.6 6.2 0.00059 20.4 0.4 2.8 1 1 1 2 2 2 2 WWE domain SAM_1 PF00536.30 PVD30931.1 - 3.8e-06 27.2 0.8 8.7e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) REC1 PF18501.1 PVD30931.1 - 0.43 10.4 5.1 0.19 11.6 2.3 1.7 2 0 0 2 2 2 0 Alpha helical recognition lobe domain AAA_23 PF13476.6 PVD30931.1 - 7.3 7.0 9.9 15 6.0 9.9 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PVD30932.1 - 8.7e-26 90.8 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD30932.1 - 1.8e-14 53.6 0.0 2.3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD30932.1 - 1.6e-09 37.1 0.1 2.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Homeodomain PF00046.29 PVD30936.1 - 2.4e-21 75.3 4.7 4.6e-21 74.4 4.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD30936.1 - 0.12 12.3 1.1 0.43 10.5 0.2 2.3 2 0 0 2 2 2 0 Homeobox KN domain DUF4627 PF15425.6 PVD30937.1 - 0.0064 16.1 0.8 0.0064 16.1 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4627) Homeodomain PF00046.29 PVD30939.1 - 3.8e-22 77.9 4.7 6.6e-22 77.1 4.7 1.4 1 0 0 1 1 1 1 Homeodomain TPX2 PF06886.11 PVD30939.1 - 0.027 14.7 2.3 0.054 13.7 2.3 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Homeobox_KN PF05920.11 PVD30939.1 - 0.052 13.5 1.2 0.094 12.6 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain Mito_fiss_reg PF05308.11 PVD30940.1 - 1 9.4 4.4 1.4 9.0 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Androgen_recep PF02166.16 PVD30940.1 - 3.3 6.4 5.9 4.1 6.2 5.9 1.1 1 0 0 1 1 1 0 Androgen receptor Rad21_Rec8_N PF04825.13 PVD30941.1 - 1.4e-15 57.4 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein RVT_1 PF00078.27 PVD30942.1 - 4.8e-15 55.7 0.0 1e-08 35.0 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 PVD30947.1 - 1.1e-15 57.6 9.3 3.2e-12 46.4 0.6 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD30947.1 - 1.8e-06 28.1 0.5 1.8e-06 28.1 0.5 3.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PVD30947.1 - 3e-05 23.8 2.0 0.00032 20.5 0.5 4.4 5 1 2 7 7 7 2 Myb DNA-binding like SLIDE PF09111.10 PVD30947.1 - 0.0029 17.6 4.4 4 7.5 0.1 3.9 3 1 1 4 4 4 2 SLIDE DUF4530 PF15039.6 PVD30947.1 - 0.13 12.4 3.1 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) BBL5 PF07289.11 PVD30948.1 - 4.8e-146 486.1 0.0 5.3e-146 485.9 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 PVD30948.1 - 3.5e-06 27.1 0.0 0.0076 16.4 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 PVD30948.1 - 2.6e-05 24.0 0.2 0.27 11.1 0.0 3.1 3 0 0 3 3 3 2 GRAM domain Voldacs PF03517.13 PVD30948.1 - 0.0035 17.5 0.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling bPH_3 PF14470.6 PVD30948.1 - 0.0079 16.5 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain PH_TFIIH PF08567.11 PVD30948.1 - 0.031 14.6 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain U6-snRNA_bdg PF10596.9 PVD30948.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 MFS_1 PF07690.16 PVD30949.1 - 4.1e-22 78.6 25.4 6e-21 74.7 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GRIP PF01465.20 PVD30950.1 - 0.00033 20.5 0.1 0.0016 18.3 0.1 2.4 1 0 0 1 1 1 1 GRIP domain DUF575 PF04746.12 PVD30950.1 - 0.51 10.6 2.1 22 5.4 0.1 4.3 2 0 0 2 2 2 0 Protein of unknown function (DUF575) PP1_bind PF15276.6 PVD30951.1 - 5.6e-14 52.2 3.0 5.6e-14 52.2 3.0 4.6 2 0 0 2 2 2 1 Protein phosphatase 1 binding FHA PF00498.26 PVD30951.1 - 9.9e-12 45.0 0.1 2.5e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD30951.1 - 8.4e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SH2 PF00017.24 PVD30952.1 - 1.4e-10 41.1 0.1 3.2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FF PF01846.19 PVD30953.1 - 8e-41 138.0 29.9 3.1e-13 49.7 0.1 7.0 7 0 0 7 7 7 6 FF domain WW PF00397.26 PVD30953.1 - 1.2e-19 70.1 14.4 5.3e-10 39.2 1.9 2.8 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 PVD30953.1 - 1.6 9.0 6.5 3.7 7.9 0.9 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain SNF2_N PF00176.23 PVD30954.1 - 1.3e-16 60.3 0.2 1.9e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.14 PVD30954.1 - 0.00056 19.9 0.1 0.0025 17.8 0.0 2.0 2 1 0 2 2 2 1 Flavivirus DEAD domain ResIII PF04851.15 PVD30954.1 - 0.0013 18.8 0.1 0.0097 15.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PVD30954.1 - 0.0023 18.3 0.1 0.015 15.6 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain FF PF01846.19 PVD30955.1 - 1.7e-32 111.3 26.1 3e-13 49.7 0.1 7.0 8 0 0 8 8 8 5 FF domain WW PF00397.26 PVD30955.1 - 1.9e-10 40.7 1.9 5.1e-10 39.3 1.9 1.8 1 0 0 1 1 1 1 WW domain SNF2_N PF00176.23 PVD30956.1 - 1.1e-29 103.3 0.2 1.9e-29 102.5 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 PVD30956.1 - 3.9e-17 61.6 0.1 9e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 HepA-related protein (HARP) Helicase_C PF00271.31 PVD30956.1 - 1.2e-14 54.6 0.0 5.8e-14 52.4 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD30956.1 - 2.4e-06 27.7 0.0 1.3e-05 25.2 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 PVD30956.1 - 0.0012 18.8 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 PVD30957.1 - 7.1e-123 408.6 0.9 4.8e-122 405.9 1.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PVD30957.1 - 1.3e-12 48.1 0.0 3.9e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PVD30957.1 - 3.3e-11 43.5 0.1 8.6e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 PVD30957.1 - 4.5e-05 23.6 0.0 0.00013 22.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 PVD30957.1 - 0.00072 18.4 0.0 0.00098 17.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4354 PF14263.6 PVD30957.1 - 0.0032 17.3 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4354) AAA_22 PF13401.6 PVD30957.1 - 0.034 14.4 0.1 0.16 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_34 PF13872.6 PVD30957.1 - 0.075 11.9 0.1 0.2 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Cryptochrome_C PF12546.8 PVD30957.1 - 0.23 12.1 1.5 0.76 10.4 0.4 2.3 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal AIP3 PF03915.13 PVD30962.1 - 1.9e-26 93.1 20.1 5.5e-18 65.3 8.8 2.7 3 0 0 3 3 3 2 Actin interacting protein 3 Baculo_PEP_C PF04513.12 PVD30962.1 - 0.013 15.5 3.6 0.11 12.5 0.5 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PVD30962.1 - 2.4 8.2 5.0 15 5.6 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TBCA PF02970.16 PVD30962.1 - 3.7 7.9 14.5 0.59 10.5 3.7 3.5 3 1 1 4 4 4 0 Tubulin binding cofactor A DUF1319 PF07028.11 PVD30962.1 - 5.8 7.2 6.0 2.2 8.5 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) CBS PF00571.28 PVD30963.1 - 3.3e-28 97.9 8.4 1.1e-08 35.4 0.1 4.6 5 0 0 5 5 5 3 CBS domain CENP-F_leu_zip PF10473.9 PVD30966.1 - 0.00045 20.3 16.4 0.00045 20.3 16.4 2.6 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 PVD30966.1 - 0.0017 18.1 3.6 0.0017 18.1 3.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 PVD30966.1 - 0.011 15.9 22.4 0.011 15.9 22.4 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FPP PF05911.11 PVD30966.1 - 0.048 11.9 28.9 2.2 6.4 28.9 2.1 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil NPV_P10 PF05531.12 PVD30966.1 - 0.19 12.2 8.9 2.4 8.7 0.3 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 PVD30966.1 - 0.2 10.5 31.7 1.1 8.0 31.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DPM3 PF08285.11 PVD30966.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.6 2 1 1 3 3 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) UPF0242 PF06785.11 PVD30966.1 - 0.55 10.3 34.0 0.51 10.4 10.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 PVD30966.1 - 0.61 10.6 38.1 3.1 8.3 16.6 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 PVD30966.1 - 0.87 9.6 21.3 2.1 8.4 4.9 3.9 2 1 2 4 4 4 0 Laminin Domain II Rx_N PF18052.1 PVD30966.1 - 1.7 9.0 19.7 12 6.2 0.0 3.9 2 1 2 4 4 4 0 Rx N-terminal domain GAS PF13851.6 PVD30966.1 - 1.7 7.9 31.5 0.024 14.0 8.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 PVD30966.1 - 2.2 7.5 35.5 1.2 8.4 11.4 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 PVD30966.1 - 3.3 7.9 38.2 2.3 8.4 10.3 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Filament PF00038.21 PVD30966.1 - 3.8 7.0 33.0 0.034 13.7 12.0 2.7 1 1 1 2 2 2 0 Intermediate filament protein DHR10 PF18595.1 PVD30966.1 - 7.8 6.6 41.1 0.048 13.7 11.1 3.9 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 PVD30966.1 - 8.3 6.2 23.1 0.38 10.5 5.4 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 ParA PF10609.9 PVD30967.1 - 1.1e-80 270.6 0.1 1.9e-80 269.9 0.1 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PVD30967.1 - 2.2e-12 47.1 0.0 5e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PVD30967.1 - 7.1e-10 39.1 0.0 8.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 PVD30967.1 - 1.2e-09 37.9 0.1 4.9e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PVD30967.1 - 4.9e-06 26.0 0.5 2.1e-05 23.9 0.1 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase MeaB PF03308.16 PVD30967.1 - 0.00019 20.5 0.2 0.00032 19.8 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 PVD30967.1 - 0.00023 20.7 0.1 0.00089 18.8 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 PVD30967.1 - 0.00025 20.7 0.1 0.00046 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PVD30967.1 - 0.00042 20.2 0.1 0.00074 19.4 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase SRP54 PF00448.22 PVD30967.1 - 0.00047 19.9 0.1 0.027 14.1 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 PVD30967.1 - 0.0022 17.5 0.1 0.0056 16.2 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 PVD30967.1 - 0.0027 17.5 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 PVD30967.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Zeta_toxin PF06414.12 PVD30967.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 PVD30967.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 PVD30967.1 - 0.019 15.5 0.1 0.032 14.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD30967.1 - 0.022 15.2 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 PVD30967.1 - 0.026 14.4 0.8 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PVD30967.1 - 0.027 14.4 0.4 0.2 11.5 0.2 2.2 2 1 1 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 PVD30967.1 - 0.028 13.6 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 PVD30967.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PVD30967.1 - 0.046 13.5 0.1 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 PVD30967.1 - 0.07 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 NTPase GTP_EFTU PF00009.27 PVD30967.1 - 0.077 12.5 0.3 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.9 PVD30967.1 - 0.082 11.8 0.1 2.6 6.8 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Hpr_kinase_C PF07475.12 PVD30967.1 - 0.095 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 PVD30967.1 - 0.096 12.7 0.4 0.56 10.2 0.5 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PVD30967.1 - 0.13 12.1 1.3 0.3 11.0 0.4 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 PVD30967.1 - 0.19 11.2 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein MFS_2 PF13347.6 PVD30968.1 - 1.4e-11 43.6 9.2 1.8e-11 43.3 9.2 1.2 1 1 0 1 1 1 1 MFS/sugar transport protein Guanylate_cyc PF00211.20 PVD30969.1 - 1.9e-104 347.0 2.2 4.9e-57 192.5 0.4 3.3 2 1 1 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 PVD30969.1 - 6.9e-89 298.9 2.5 6.9e-89 298.9 2.5 2.3 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 PVD30969.1 - 2.3e-13 50.6 0.2 5.1e-13 49.5 0.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Na_Ca_ex PF01699.24 PVD30970.1 - 3.9e-27 95.1 17.3 3.8e-26 91.8 11.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zf-C2H2 PF00096.26 PVD30971.1 - 7.2e-18 64.0 16.0 1.6e-06 28.2 3.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD30971.1 - 1.5e-17 63.1 20.7 2.8e-09 37.0 0.3 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD30971.1 - 1e-12 47.7 13.9 0.00012 22.7 2.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PVD30971.1 - 3.7e-05 23.5 8.5 0.23 11.4 0.3 3.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 PVD30971.1 - 7.5e-05 22.6 7.6 0.004 17.1 1.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD30971.1 - 0.00013 22.2 2.8 0.41 11.0 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 PVD30971.1 - 0.023 14.6 1.0 0.074 13.1 0.6 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-met PF12874.7 PVD30971.1 - 0.026 14.9 6.3 0.54 10.7 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD30971.1 - 0.049 13.4 5.4 6.6 6.6 0.4 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type Zf_RING PF16744.5 PVD30971.1 - 0.078 13.1 0.8 4.9 7.3 0.1 2.5 1 1 1 2 2 2 0 KIAA1045 RING finger zf-BED PF02892.15 PVD30971.1 - 0.083 12.9 5.7 0.19 11.8 2.0 2.6 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_15 PF17032.5 PVD30971.1 - 0.27 12.0 2.6 0.76 10.6 0.5 2.3 1 1 2 3 3 3 0 zinc-ribbon family C1_2 PF03107.16 PVD30971.1 - 0.4 11.0 5.1 13 6.2 2.0 3.1 2 1 0 2 2 2 0 C1 domain zf-C2H2_3rep PF18868.1 PVD30971.1 - 0.55 10.9 3.2 14 6.4 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 PVD30971.1 - 0.74 10.2 5.1 2.2 8.6 0.3 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 PVD30971.1 - 1 8.4 3.1 13 4.8 3.1 2.0 1 1 0 1 1 1 0 Putative actin-like family zf_ZIC PF18366.1 PVD30971.1 - 1.5 9.0 4.0 20 5.4 0.7 2.7 2 1 1 3 3 2 0 Zic proteins zinc finger domain HNH PF01844.23 PVD30971.1 - 3.5 7.9 8.9 3.2 8.0 0.3 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-C2HE PF16278.5 PVD30971.1 - 3.7 8.1 5.3 6.4 7.3 0.6 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 PVD30971.1 - 4.9 6.9 5.8 1.3 8.7 1.1 2.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RRN7 PF11781.8 PVD30971.1 - 8.7 6.1 8.3 6.3 6.6 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-AN1 PF01428.16 PVD30971.1 - 9 6.6 7.9 31 4.8 1.6 2.7 1 1 0 2 2 2 0 AN1-like Zinc finger PCO_ADO PF07847.12 PVD30973.1 - 9.8e-50 168.8 0.0 1.3e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 PCO_ADO BAR PF03114.18 PVD30974.1 - 4.2e-13 49.5 6.5 5.8e-13 49.0 6.5 1.3 1 0 0 1 1 1 1 BAR domain Vps5 PF09325.10 PVD30974.1 - 8.5e-06 25.5 3.2 8.5e-06 25.5 3.2 1.9 1 1 1 3 3 3 1 Vps5 C terminal like Allexi_40kDa PF05549.11 PVD30974.1 - 0.053 13.0 1.3 0.069 12.7 1.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Tnp_22_trimer PF17489.2 PVD30974.1 - 0.22 11.5 2.9 17 5.5 0.1 3.0 3 0 0 3 3 3 0 L1 transposable element trimerization domain Snapin_Pallidin PF14712.6 PVD30974.1 - 1.8 9.0 9.4 4 7.9 0.1 3.1 3 2 1 4 4 4 0 Snapin/Pallidin G-alpha PF00503.20 PVD30976.1 - 7.4e-88 295.1 0.3 9.2e-88 294.8 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD30976.1 - 3e-15 56.1 0.1 1.7e-10 40.6 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 PVD30976.1 - 0.00099 19.3 0.3 1.3 9.2 0.1 3.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 PVD30976.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 PVD30976.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 PVD30976.1 - 0.047 13.8 0.0 9.9 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 PVD30976.1 - 0.051 13.6 0.6 0.67 10.0 0.3 2.6 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PVD30976.1 - 0.085 13.1 0.0 0.38 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD30976.1 - 0.085 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PVD30976.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 PVD30976.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD30976.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 PVD30977.1 - 5.1e-21 75.2 0.0 6.5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD30977.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family TsaE PF02367.17 PVD30977.1 - 0.021 14.8 0.5 0.22 11.5 0.5 2.1 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PVD30977.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 PVD30977.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase IIGP PF05049.13 PVD30977.1 - 0.027 13.6 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.6 PVD30977.1 - 0.029 14.6 0.0 0.12 12.6 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD30977.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD30977.1 - 0.054 14.0 0.1 0.089 13.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 PVD30977.1 - 0.059 13.3 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 PVD30977.1 - 0.078 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PVD30977.1 - 0.083 12.2 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 PVD30977.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ndr PF03096.14 PVD30978.1 - 1.6e-80 269.8 0.1 2e-80 269.5 0.1 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 PVD30978.1 - 0.0064 16.2 0.0 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD30978.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_34 PF11312.8 PVD30978.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.3 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase His_Phos_2 PF00328.22 PVD30980.1 - 3.1e-28 99.2 0.2 4.2e-25 88.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Aminotran_5 PF00266.19 PVD30981.1 - 5.5e-39 134.2 0.0 1.9e-36 125.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V zf-C2H2 PF00096.26 PVD30981.1 - 1.2e-06 28.7 19.2 0.0011 19.3 2.6 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type RBFA PF02033.18 PVD30981.1 - 6.3e-06 26.6 15.2 2.6 8.5 0.2 5.8 1 1 4 6 6 6 5 Ribosome-binding factor A zf-C2H2_11 PF16622.5 PVD30981.1 - 0.00025 20.7 16.7 0.012 15.4 3.5 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 PVD30981.1 - 0.00032 21.3 19.0 0.016 16.0 2.0 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PVD30981.1 - 0.17 11.6 9.2 0.55 9.9 1.1 3.2 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 PVD30981.1 - 0.26 11.6 6.1 0.46 10.8 0.6 3.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TpcC PF12642.7 PVD30981.1 - 1.6 8.5 5.2 0.5 10.1 0.7 2.2 1 1 1 2 2 2 0 Conjugative transposon protein TcpC zf-C2H2_6 PF13912.6 PVD30981.1 - 1.8 8.7 9.9 0.22 11.5 0.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger His_Phos_2 PF00328.22 PVD30982.1 - 7.1e-19 68.4 0.1 3.2e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) 7tm_2 PF00002.24 PVD30985.1 - 2.8e-72 243.0 16.7 4e-72 242.4 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD30985.1 - 1.4e-14 54.1 4.0 1.4e-14 54.1 4.0 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF2628 PF10947.8 PVD30985.1 - 3.9 7.9 14.9 1.1 9.7 9.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) P34-Arc PF04045.14 PVD30986.1 - 3.8e-96 321.4 2.4 4.9e-96 321.1 2.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc CxC3 PF18804.1 PVD30990.1 - 5.4e-10 39.1 0.2 8.9e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 PVD30990.1 - 0.0055 16.9 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Aldo_ket_red PF00248.21 PVD30990.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD30991.1 - 1.5e-66 224.6 0.0 1.9e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Carn_acyltransf PF00755.20 PVD30992.1 - 1.6e-112 377.1 0.0 1.8e-98 330.7 0.0 2.5 1 1 2 3 3 3 3 Choline/Carnitine o-acyltransferase TMIE PF16038.5 PVD30993.1 - 2.9e-22 78.3 1.8 5.6e-22 77.4 1.8 1.5 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 PVD30993.1 - 0.0028 17.9 0.4 0.0051 17.1 0.4 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Cytadhesin_P30 PF07271.11 PVD30993.1 - 0.009 15.6 0.2 0.011 15.4 0.2 1.1 1 0 0 1 1 1 1 Cytadhesin P30/P32 LRR19-TM PF15176.6 PVD30993.1 - 0.048 13.7 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Peptidase_S49_N PF08496.10 PVD30993.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF575 PF04746.12 PVD30993.1 - 0.59 10.4 2.9 0.64 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF575) ShK PF01549.24 PVD30995.1 - 2.8e-23 82.1 59.0 8.5e-07 29.4 9.9 4.1 4 0 0 4 4 4 4 ShK domain-like TACC_C PF05010.14 PVD30996.1 - 3.6e-54 183.6 36.7 3.6e-54 183.6 36.7 1.6 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APG6_N PF17675.1 PVD30996.1 - 0.00022 21.8 22.3 0.00022 21.8 22.3 3.2 1 1 2 3 3 3 1 Apg6 coiled-coil region Fib_alpha PF08702.10 PVD30996.1 - 0.0054 16.9 14.6 0.0054 16.9 14.6 3.0 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 PVD30996.1 - 0.012 16.2 40.9 0.69 10.6 7.6 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IFT57 PF10498.9 PVD30996.1 - 0.11 11.4 30.3 0.16 10.9 30.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2185 PF09951.9 PVD30996.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2185) DUF948 PF06103.11 PVD30996.1 - 0.2 11.9 20.7 0.59 10.4 4.3 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 PVD30996.1 - 0.28 10.5 41.5 0.047 13.0 30.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_DE PF00401.20 PVD30996.1 - 0.5 10.7 15.1 0.14 12.5 5.6 3.3 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HMMR_N PF15905.5 PVD30996.1 - 0.52 9.7 45.6 0.36 10.2 28.9 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 PVD30996.1 - 0.61 8.0 19.8 1.5 6.7 19.8 1.6 1 1 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 PVD30996.1 - 0.75 9.8 16.2 3.5 7.7 2.1 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2277 PF10041.9 PVD30996.1 - 2.5 8.5 6.4 4 7.9 1.0 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2277) DUF1993 PF09351.10 PVD30996.1 - 3.9 7.6 13.7 2.8 8.1 3.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1993) FAM184 PF15665.5 PVD30996.1 - 3.9 7.2 46.1 0.11 12.3 24.8 3.0 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Syntaxin-6_N PF09177.11 PVD30996.1 - 5.2 7.7 24.1 7.6 7.2 7.2 3.9 2 1 2 4 4 4 0 Syntaxin 6, N-terminal FUSC PF04632.12 PVD30996.1 - 6.8 5.1 13.2 3.4 6.1 5.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 PVD30996.1 - 7.9 6.5 27.1 0.94 9.5 4.3 3.3 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) ASH PF15780.5 PVD30997.1 - 8.2e-07 29.2 0.0 0.017 15.3 0.1 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PVD30997.1 - 9.6e-07 28.9 0.0 4.3e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 PVD30997.1 - 0.015 15.2 0.2 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 MSP (Major sperm protein) domain TMEM131_like PF12371.8 PVD30997.1 - 0.16 12.3 2.0 0.56 10.5 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 131-like Thioesterase PF00975.20 PVD30998.1 - 6e-27 95.2 0.0 9.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 PVD30998.1 - 0.00013 22.6 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD30998.1 - 0.00014 21.2 0.0 0.00083 18.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD30998.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PVD30998.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 PVD30998.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 PVD30998.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 PVD30998.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.16 PVD30999.1 - 3.7e-10 39.3 1.7 3.7e-10 39.3 1.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Neur_chan_LBD PF02931.23 PVD31000.1 - 9.5e-68 227.9 0.5 1.5e-34 119.3 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31000.1 - 1.6e-07 31.7 1.2 1.6e-07 31.7 1.2 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF5534 PF17686.1 PVD31000.1 - 0.095 13.0 1.9 11 6.3 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5534) DUF2842 PF11003.8 PVD31000.1 - 0.22 11.8 7.6 7.6 6.9 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) MscS_TM PF12794.7 PVD31000.1 - 0.91 8.3 9.3 0.11 11.3 3.6 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Neur_chan_LBD PF02931.23 PVD31001.1 - 5.8e-29 101.1 0.3 7.1e-29 100.8 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31001.1 - 2.8e-07 30.8 1.9 3.9e-07 30.4 1.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD31002.1 - 1.4e-38 132.5 3.4 1.9e-38 132.1 3.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31002.1 - 3.5e-09 37.1 4.0 3.5e-09 37.1 4.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD31003.1 - 2.4e-25 89.3 0.2 2.4e-21 76.2 0.3 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31003.1 - 5.7e-16 59.3 6.1 5.7e-16 59.3 6.1 2.1 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD31004.1 - 5.5e-30 104.4 0.4 8.6e-30 103.8 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31004.1 - 6.3e-13 49.3 11.6 3e-11 43.8 5.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4436 PF14494.6 PVD31004.1 - 0.0059 15.9 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) LRR_8 PF13855.6 PVD31005.1 - 2.4e-13 49.6 6.2 2.1e-11 43.4 0.5 3.0 2 1 1 3 3 3 3 Leucine rich repeat Ig_3 PF13927.6 PVD31005.1 - 1.7e-10 41.4 0.1 4.1e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD31005.1 - 3.7e-07 30.1 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD31005.1 - 3e-06 27.5 0.1 7.9e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 PVD31005.1 - 3.5e-05 23.7 2.2 0.26 12.0 0.1 5.2 4 1 0 4 4 4 1 Leucine Rich Repeat LRRNT PF01462.18 PVD31005.1 - 0.00013 21.5 5.0 0.00013 21.5 5.0 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PVD31005.1 - 0.00023 21.5 8.6 0.27 11.7 1.6 4.1 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD31005.1 - 0.0033 17.4 0.2 0.0058 16.6 0.2 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 PVD31005.1 - 0.007 16.5 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD31005.1 - 0.15 12.2 0.1 0.46 10.7 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin V-set domain E1_DerP2_DerF2 PF02221.15 PVD31006.1 - 0.073 13.5 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 ML domain zf-C4 PF00105.18 PVD31007.1 - 1.7e-23 82.8 14.3 3.7e-23 81.7 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD31007.1 - 1.4e-11 44.4 6.5 2.8e-11 43.4 6.5 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF5424 PF17462.2 PVD31007.1 - 0.0023 17.9 1.9 0.09 12.7 0.1 2.8 2 1 1 3 3 3 1 Family of unknown function (DUF5424) zf-RRPl_C4 PF17026.5 PVD31007.1 - 0.47 10.6 12.0 0.29 11.3 8.4 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type RPA_interact_C PF14768.6 PVD31007.1 - 1.6 9.3 10.4 16 6.2 7.3 2.7 2 0 0 2 2 2 0 Replication protein A interacting C-terminal zf-C4 PF00105.18 PVD31008.1 - 1.4e-25 89.5 9.6 4.1e-25 88.0 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD31008.1 - 9.4e-09 35.1 0.8 2.2e-08 33.9 0.8 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Transp_Tc5_C PF04236.15 PVD31008.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.0 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain zf-RRPl_C4 PF17026.5 PVD31008.1 - 6.2 7.0 10.9 0.46 10.6 5.1 2.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C4 PF00105.18 PVD31009.1 - 1.6e-22 79.7 15.1 3.3e-22 78.7 15.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD31009.1 - 1.3e-06 28.2 5.8 2e-06 27.6 2.7 2.7 3 1 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor DUF3565 PF12088.8 PVD31009.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3565) zf-RRPl_C4 PF17026.5 PVD31009.1 - 2.4 8.3 14.8 0.57 10.3 7.7 2.6 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C4 PF00105.18 PVD31010.1 - 4.5e-07 30.2 3.0 7.6e-07 29.5 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PGM_PMM_I PF02878.16 PVD31011.1 - 9.8e-19 67.4 0.1 1.6e-08 34.4 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 PVD31011.1 - 1.2e-11 44.6 0.3 3.4e-11 43.2 0.3 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 PVD31011.1 - 3.3e-05 24.1 0.1 8.7e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PVD31011.1 - 0.06 14.0 1.4 0.66 10.6 0.7 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II An_peroxidase PF03098.15 PVD31012.1 - 3.8e-122 408.6 0.0 3.6e-63 214.0 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase Lectin_C PF00059.21 PVD31016.1 - 2.8e-24 85.9 1.3 1.5e-11 45.0 0.5 2.5 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD31016.1 - 7.5e-06 25.7 0.2 1.4e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like ShK PF01549.24 PVD31016.1 - 3.5e-05 24.2 4.8 3.5e-05 24.2 4.8 3.5 3 0 0 3 3 3 1 ShK domain-like Chordopox_A33R PF05966.12 PVD31016.1 - 0.0025 17.1 1.1 0.004 16.4 0.5 1.6 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 PVD31017.1 - 7.4e-21 74.9 0.4 4.6e-09 37.0 0.0 3.6 2 1 1 3 3 3 3 Lectin C-type domain ApeC PF16977.5 PVD31017.1 - 1.5e-20 74.0 1.3 1.5e-20 74.0 1.3 3.6 3 1 1 4 4 4 1 C-terminal domain of apextrin CUB PF00431.20 PVD31017.1 - 1.8e-11 44.3 0.0 4.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 CUB domain Kringle PF00051.18 PVD31017.1 - 2.4e-08 34.2 0.3 2.4e-08 34.2 0.3 2.4 2 0 0 2 2 2 1 Kringle domain Astacin PF01400.24 PVD31017.1 - 1.2e-06 28.2 0.0 0.0018 17.9 0.0 2.5 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) ShK PF01549.24 PVD31017.1 - 0.019 15.5 7.2 0.053 14.1 5.2 3.0 2 0 0 2 2 2 0 ShK domain-like Xlink PF00193.17 PVD31017.1 - 0.041 14.3 0.3 4.1 7.8 0.0 3.5 3 0 0 3 3 3 0 Extracellular link domain Pox_A11 PF05061.13 PVD31018.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein ABC_membrane PF00664.23 PVD31019.1 - 7.7e-76 255.3 27.9 2e-40 139.2 4.6 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 PVD31019.1 - 3.8e-53 179.7 0.1 7.9e-31 107.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD31019.1 - 1e-13 51.3 0.5 5.1e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PVD31019.1 - 1.7e-08 33.7 0.3 4.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class SbcCD_C PF13558.6 PVD31019.1 - 1.2e-05 25.5 0.5 0.43 10.9 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 PVD31019.1 - 1.9e-05 25.1 0.8 0.00031 21.2 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD31019.1 - 0.00012 22.3 0.3 0.074 13.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 PVD31019.1 - 0.00033 21.1 0.7 14 6.1 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 PVD31019.1 - 0.00039 20.3 0.0 0.56 10.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PVD31019.1 - 0.00091 18.8 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 PVD31019.1 - 0.0025 17.8 0.2 0.13 12.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 PVD31019.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ATP-synt_ab PF00006.25 PVD31019.1 - 0.0052 16.5 1.1 0.019 14.7 0.0 2.5 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain CRAL_TRIO PF00650.20 PVD31019.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO domain AAA_29 PF13555.6 PVD31019.1 - 0.028 14.2 0.4 0.067 13.0 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 PVD31019.1 - 0.039 13.9 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 PVD31019.1 - 0.073 12.8 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1_C PF08438.10 PVD31019.1 - 0.17 12.5 0.2 3.4 8.3 0.0 2.6 2 0 0 2 2 2 0 GTPase of unknown function C-terminal AAA_25 PF13481.6 PVD31019.1 - 0.25 10.9 1.6 2.9 7.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain Rubella_Capsid PF05750.11 PVD31021.1 - 0.061 12.9 0.2 0.065 12.8 0.2 1.0 1 0 0 1 1 1 0 Rubella capsid protein ABC_membrane PF00664.23 PVD31022.1 - 2.1e-126 421.2 34.6 1.4e-65 221.7 13.8 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD31022.1 - 6e-73 243.8 0.2 6.4e-37 127.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD31022.1 - 3.1e-17 62.8 0.0 1.1e-06 28.2 0.0 3.5 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PVD31022.1 - 8.3e-11 41.3 0.2 2.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 PVD31022.1 - 5e-10 40.0 2.4 0.00042 20.7 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PVD31022.1 - 2.1e-09 37.8 0.3 0.00091 19.5 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 PVD31022.1 - 1.7e-06 28.0 0.2 0.39 10.5 0.0 4.1 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PVD31022.1 - 1.9e-06 27.6 0.0 0.0049 16.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 PVD31022.1 - 2.1e-06 27.1 5.7 0.04 13.2 0.0 4.1 5 0 0 5 5 3 2 Zeta toxin RsgA_GTPase PF03193.16 PVD31022.1 - 8.3e-06 25.8 0.1 0.087 12.7 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 PVD31022.1 - 8.5e-06 25.9 4.5 0.18 12.1 0.4 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 PVD31022.1 - 1.4e-05 25.1 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 PVD31022.1 - 4.1e-05 23.6 0.2 0.58 10.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PVD31022.1 - 8.8e-05 22.3 5.5 0.22 11.2 0.4 3.4 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 PVD31022.1 - 0.00021 21.2 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Viral_helicase1 PF01443.18 PVD31022.1 - 0.00024 20.9 0.0 0.39 10.4 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 PVD31022.1 - 0.00025 21.3 0.7 1.6 9.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 PVD31022.1 - 0.00043 20.0 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 PVD31022.1 - 0.00061 19.5 3.6 0.4 10.3 0.0 3.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 PVD31022.1 - 0.00074 18.8 0.0 0.44 9.7 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit AAA_29 PF13555.6 PVD31022.1 - 0.00076 19.2 4.1 0.67 9.7 0.4 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.29 PVD31022.1 - 0.0016 18.9 7.1 1.7 9.1 0.2 4.6 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 PVD31022.1 - 0.0037 17.0 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 PVD31022.1 - 0.0039 16.4 0.1 0.93 8.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 PVD31022.1 - 0.0048 17.4 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PVD31022.1 - 0.0081 16.2 0.0 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 PVD31022.1 - 0.0093 16.3 0.1 8.8 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase HCV_NS5a_1b PF08301.13 PVD31022.1 - 0.025 15.1 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b AAA_33 PF13671.6 PVD31022.1 - 0.031 14.4 0.0 13 6.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PVD31022.1 - 0.042 13.2 0.0 2 7.8 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 PVD31022.1 - 0.046 14.0 1.2 3.6 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 PVD31022.1 - 0.062 12.9 0.1 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 PVD31022.1 - 0.081 13.0 0.1 22 5.0 0.0 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 PVD31022.1 - 0.091 12.7 0.3 7.9 6.3 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 PVD31022.1 - 0.11 13.0 1.0 17 5.8 0.1 3.3 2 1 0 2 2 2 0 AAA domain Herpes_US12 PF05363.12 PVD31022.1 - 0.16 12.7 0.1 1.2 9.8 0.0 2.5 2 0 0 2 2 1 0 Herpesvirus US12 family NB-ARC PF00931.22 PVD31022.1 - 0.29 10.3 3.4 12 4.9 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain DUF2852 PF11014.8 PVD31022.1 - 6.4 6.9 10.5 1.9 8.6 0.1 3.6 4 1 1 5 5 2 0 Protein of unknown function (DUF2852) 3HCDH_N PF02737.18 PVD31023.1 - 4.4e-40 137.5 0.3 2.6e-35 121.9 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 PVD31023.1 - 3.1e-34 118.4 0.0 5.5e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 PVD31023.1 - 3.2e-30 104.6 0.0 4.4e-20 72.1 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 PVD31023.1 - 1.1e-19 71.1 0.0 2.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 PVD31023.1 - 0.0005 20.3 0.3 0.0012 19.0 0.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 PVD31023.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PVD31023.1 - 0.0035 17.9 0.2 0.008 16.7 0.2 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PVD31023.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 PVD31023.1 - 0.0082 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD31023.1 - 0.0085 15.7 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 PVD31023.1 - 0.014 15.7 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 PVD31023.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 PVD31023.1 - 0.03 14.7 0.1 0.097 13.1 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 PVD31023.1 - 0.047 14.3 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 PVD31023.1 - 0.058 13.5 0.5 0.25 11.4 0.1 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.7 PVD31024.1 - 7.8e-08 32.1 3.0 3e-07 30.2 3.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD31024.1 - 3.5e-06 26.7 0.7 3.5e-06 26.7 0.7 2.3 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 PVD31024.1 - 6.1e-06 25.9 2.2 4.5 7.6 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat F-box_4 PF15966.5 PVD31024.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 2.2 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 PVD31024.1 - 0.012 16.0 14.1 1 9.9 0.2 5.5 3 1 5 8 8 8 0 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 PVD31025.1 - 4.4e-29 101.6 6.7 1.8e-23 83.2 1.9 3.2 3 0 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31025.1 - 1.1e-10 41.4 24.8 4e-07 29.7 13.0 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31025.1 - 1.3e-07 31.6 15.6 1.3e-07 31.6 15.6 2.2 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Amnionless PF14828.6 PVD31025.1 - 0.0076 15.1 0.7 0.1 11.4 0.1 2.2 2 0 0 2 2 2 1 Amnionless DUF4006 PF13179.6 PVD31025.1 - 0.62 10.0 9.8 6 6.9 2.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF4006) TUDOR PF00567.24 PVD31026.1 - 7.4e-48 161.6 0.0 1.1e-23 83.6 0.0 3.2 2 1 0 2 2 2 2 Tudor domain SMN PF06003.12 PVD31026.1 - 9e-07 28.4 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) Agenet PF05641.12 PVD31026.1 - 6.9e-06 26.4 0.9 0.61 10.6 0.1 3.4 3 0 0 3 3 3 2 Agenet domain SAWADEE PF16719.5 PVD31026.1 - 0.00016 21.7 0.2 0.09 12.8 0.0 2.9 3 0 0 3 3 3 2 SAWADEE domain DUF4537 PF15057.6 PVD31026.1 - 0.00063 19.8 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DUF1325 PF07039.11 PVD31026.1 - 0.05 13.7 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 SGF29 tudor-like domain Tap-RNA_bind PF09162.10 PVD31026.1 - 0.082 12.8 0.4 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 Tap, RNA-binding Tudor_4 PF18358.1 PVD31026.1 - 0.16 11.6 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain fn3 PF00041.21 PVD31027.1 - 0.00025 21.3 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain 7tm_1 PF00001.21 PVD31028.1 - 9e-13 48.1 6.1 1.6e-12 47.3 6.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31028.1 - 1.3e-06 28.0 7.0 2e-06 27.4 7.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31028.1 - 0.00049 19.8 5.9 0.00071 19.3 5.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF872 PF05915.12 PVD31028.1 - 0.0074 16.5 2.2 0.92 9.7 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF872) TMC PF07810.13 PVD31028.1 - 0.3 11.7 3.0 0.54 10.9 3.0 1.4 1 0 0 1 1 1 0 TMC domain DUF4006 PF13179.6 PVD31028.1 - 0.84 9.6 2.9 0.91 9.5 1.4 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF4006) HMG_box PF00505.19 PVD31029.1 - 7.5e-05 23.1 0.7 0.00014 22.2 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box TUDOR PF00567.24 PVD31030.1 - 8.2e-69 229.3 1.2 1.3e-25 89.8 0.0 6.3 4 1 2 6 6 6 6 Tudor domain Agenet PF05641.12 PVD31030.1 - 4.3e-06 27.1 5.2 0.21 12.1 0.1 5.3 5 0 0 5 5 5 2 Agenet domain DUF4537 PF15057.6 PVD31030.1 - 0.0001 22.3 0.2 0.98 9.5 0.1 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF4537) SAWADEE PF16719.5 PVD31030.1 - 0.00014 21.9 0.7 0.22 11.5 0.0 4.0 4 0 0 4 4 4 2 SAWADEE domain SMN PF06003.12 PVD31030.1 - 0.00048 19.5 0.0 1.1 8.5 0.0 2.7 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) Cu-oxidase PF00394.22 PVD31030.1 - 0.021 15.0 0.5 39 4.3 0.1 4.3 5 0 0 5 5 5 0 Multicopper oxidase PrgU PF09627.10 PVD31030.1 - 0.077 13.0 0.1 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 PrgU-like protein Tudor_4 PF18358.1 PVD31030.1 - 0.16 11.6 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 7tm_1 PF00001.21 PVD31031.1 - 5.9e-32 111.0 29.4 4.8e-15 55.6 1.2 4.2 3 1 1 4 4 4 4 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31031.1 - 7.3e-10 38.7 34.3 0.00052 19.5 6.8 3.7 4 0 0 4 4 4 3 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31031.1 - 1.2e-06 28.4 28.4 1.9e-05 24.4 6.8 3.4 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF2583 PF10762.9 PVD31031.1 - 9.9 6.7 6.1 5.1 7.6 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) 7tm_1 PF00001.21 PVD31032.1 - 3.2e-26 92.2 13.4 4.1e-26 91.9 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31032.1 - 1.6e-14 53.9 18.7 1.5e-10 40.9 9.3 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31032.1 - 2.2e-07 30.8 12.8 2.2e-07 30.8 12.8 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SH3_1 PF00018.28 PVD31033.1 - 1.1e-51 172.1 12.4 7.2e-13 47.9 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 PVD31033.1 - 4.2e-45 151.2 1.9 5.2e-09 35.7 0.0 6.0 6 0 0 6 6 6 5 Variant SH3 domain SH3_9 PF14604.6 PVD31033.1 - 1.3e-43 146.6 9.6 8.5e-09 35.1 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_3 PF08239.11 PVD31033.1 - 1.5e-20 73.2 19.4 2.6e-05 24.4 0.6 6.0 6 0 0 6 6 6 4 Bacterial SH3 domain PX PF00787.24 PVD31033.1 - 5.9e-16 58.5 0.0 1.8e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_4 PF06347.13 PVD31033.1 - 4.9e-12 45.5 16.9 0.0053 16.6 0.1 5.5 5 0 0 5 5 5 4 Bacterial SH3 domain Helicase_C PF00271.31 PVD31033.1 - 8.1e-11 42.2 0.9 1.6e-07 31.6 0.1 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD31033.1 - 7.6e-10 38.8 0.6 7.3e-09 35.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ShK PF01549.24 PVD31033.1 - 9.8e-07 29.2 64.2 0.075 13.6 9.5 6.2 5 0 0 5 5 5 4 ShK domain-like SH3_16 PF18348.1 PVD31033.1 - 3.3e-05 23.6 16.6 0.22 11.4 0.2 4.9 5 0 0 5 5 5 3 Bacterial dipeptidyl-peptidase Sh3 domain HHH_5 PF14520.6 PVD31033.1 - 0.00013 22.5 0.0 0.00032 21.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SH3_6 PF12913.7 PVD31033.1 - 0.019 14.5 5.2 1.3 8.6 0.2 3.5 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) SH3_10 PF17902.1 PVD31033.1 - 0.024 14.7 6.9 0.29 11.2 0.1 4.3 5 0 0 5 5 5 0 SH3 domain DUF4332 PF14229.6 PVD31033.1 - 0.035 14.3 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) ISG65-75 PF11727.8 PVD31034.1 - 1.5 8.0 5.9 25 4.0 0.0 3.1 3 0 0 3 3 3 0 Invariant surface glycoprotein MFS_1 PF07690.16 PVD31035.1 - 2.9e-10 39.6 44.6 4e-06 26.0 24.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Herp-Cyclin PF09241.10 PVD31037.1 - 0.34 11.6 1.6 0.91 10.2 1.6 1.7 1 0 0 1 1 1 0 Herpesviridae viral cyclin 7tm_1 PF00001.21 PVD31038.1 - 3.7e-08 33.0 0.2 4.1e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD31039.1 - 1.9e-20 73.3 4.6 2.6e-20 72.8 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD31039.1 - 0.00032 20.2 6.8 0.0097 15.3 0.7 2.2 1 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD31039.1 - 0.0028 17.0 0.1 0.0046 16.3 0.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Abhydrolase_9_N PF15420.6 PVD31039.1 - 0.013 15.5 3.0 0.032 14.2 2.9 1.7 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Oxidored_q3 PF00499.20 PVD31039.1 - 0.048 13.4 1.5 0.068 12.9 0.6 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 7tm_4 PF13853.6 PVD31039.1 - 0.17 11.6 3.2 0.39 10.4 3.2 1.7 1 1 0 1 1 1 0 Olfactory receptor DUF3671 PF12420.8 PVD31039.1 - 0.2 11.7 0.9 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function Phage_terminase PF10668.9 PVD31041.1 - 0.0047 16.9 0.0 0.025 14.6 0.0 2.3 1 0 0 1 1 1 1 Phage terminase small subunit CENP-H PF05837.12 PVD31041.1 - 0.011 16.1 18.3 0.011 16.1 18.3 10.5 2 2 8 11 11 11 0 Centromere protein H (CENP-H) Serpin PF00079.20 PVD31042.1 - 1.2e-59 202.6 0.0 2e-58 198.5 0.0 2.5 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Dyp_perox PF04261.12 PVD31043.1 - 5.6e-41 140.6 0.0 9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Dyp-type peroxidase family GrpE PF01025.19 PVD31043.1 - 7.4e-22 77.8 3.0 1.5e-21 76.7 3.0 1.4 1 0 0 1 1 1 1 GrpE HMMR_C PF15908.5 PVD31043.1 - 0.015 15.5 1.4 0.038 14.2 1.4 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF998 PF06197.13 PVD31043.1 - 0.04 13.5 3.4 0.064 12.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Phage_TAC_8 PF10666.9 PVD31043.1 - 0.13 12.6 2.0 2.2 8.6 1.2 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 CLZ PF16526.5 PVD31043.1 - 0.33 11.3 4.5 1.3 9.4 4.5 2.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MFS_1 PF07690.16 PVD31044.1 - 2.1e-39 135.4 33.8 5.1e-38 130.9 32.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 PVD31044.1 - 0.0011 17.4 0.2 0.002 16.5 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) MFS_1_like PF12832.7 PVD31044.1 - 1 8.1 19.2 0.74 8.6 4.6 2.2 1 1 1 2 2 2 0 MFS_1 like family Xan_ur_permease PF00860.20 PVD31045.1 - 7.8e-62 209.2 28.3 1.1e-61 208.7 28.3 1.2 1 0 0 1 1 1 1 Permease family CAP_N PF01213.19 PVD31046.1 - 0.28 10.6 6.7 0.32 10.5 6.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD31046.1 - 0.47 10.5 4.2 0.56 10.2 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Sulfotransfer_1 PF00685.27 PVD31048.1 - 3.9e-16 59.3 0.1 4.1e-14 52.7 0.3 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31048.1 - 1.8e-15 57.9 0.8 5.1e-08 33.6 0.8 3.2 1 1 1 2 2 2 2 Sulfotransferase family Cu-oxidase_3 PF07732.15 PVD31049.1 - 3.2e-19 69.1 1.2 1.2e-05 25.4 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD31049.1 - 1.6e-18 66.8 12.0 1.5e-14 53.9 1.6 5.5 5 2 0 5 5 5 2 Multicopper oxidase Lenti_VIF_2 PF07401.12 PVD31050.1 - 0.33 10.3 1.1 14 5.0 0.2 2.2 2 0 0 2 2 2 0 Bovine Lentivirus VIF protein LRR_8 PF13855.6 PVD31051.1 - 0.0007 19.3 2.2 0.35 10.7 1.6 3.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 PVD31051.1 - 0.0055 16.7 0.2 5.9 7.2 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 PVD31051.1 - 0.022 15.2 3.3 2.6 8.6 0.4 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD31052.1 - 0.0011 18.8 7.0 0.13 12.4 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 PVD31052.1 - 0.075 12.8 7.3 0.32 10.8 1.1 4.5 2 2 1 3 3 3 0 Leucine rich repeat PHD_4 PF16866.5 PVD31052.1 - 0.084 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 PHD-finger tRNA_NucTran2_2 PF13735.6 PVD31052.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative CARD_2 PF16739.5 PVD31053.1 - 2.6e-06 27.3 0.2 9.1e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 Caspase recruitment domain CLTH PF10607.9 PVD31056.1 - 3.2e-30 105.0 0.3 5e-30 104.4 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain 2-Hacid_dh_C PF02826.19 PVD31057.1 - 1.4e-55 187.4 0.0 2.4e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD31057.1 - 2.1e-29 101.9 0.0 2.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PVD31057.1 - 0.0025 18.0 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF677 PF05055.12 PVD31058.1 - 0.0075 15.2 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Ribosomal_S18 PF01084.20 PVD31059.1 - 0.00029 21.0 0.1 0.00076 19.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 EKR PF10371.9 PVD31059.1 - 0.11 12.3 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function ELMO_CED12 PF04727.13 PVD31060.1 - 1e-30 107.2 0.0 2.4e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family RNA_pol_Rpb2_6 PF00562.28 PVD31061.1 - 4.2e-125 417.9 0.0 5.6e-125 417.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PVD31061.1 - 9.1e-69 231.0 0.0 1.3e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 PVD31061.1 - 6e-55 185.8 0.0 1.7e-54 184.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 PVD31061.1 - 6e-25 87.2 0.0 1.5e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PVD31061.1 - 1.9e-23 82.5 0.3 5.6e-23 81.0 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.20 PVD31061.1 - 1.9e-22 79.4 0.2 5.6e-22 78.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 PVD31061.1 - 8.4e-18 64.7 1.2 2e-17 63.5 1.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Syja_N PF02383.18 PVD31062.1 - 8.9e-71 238.8 0.0 1.1e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ribosomal_S10 PF00338.22 PVD31062.1 - 0.13 12.5 0.5 1.9 8.8 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein S10p/S20e 7tm_1 PF00001.21 PVD31063.1 - 5.4e-72 242.3 8.2 5.4e-72 242.3 8.2 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31063.1 - 3.1e-12 46.4 20.8 2.3e-09 37.0 11.3 2.5 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31063.1 - 1.7e-06 27.9 20.3 1.7e-06 27.9 20.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD31063.1 - 0.05 13.3 10.1 0.13 12.0 7.8 2.2 2 0 0 2 2 2 0 Olfactory receptor 7tm_1 PF00001.21 PVD31065.1 - 2.2e-72 243.6 6.9 2.2e-72 243.6 6.9 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31065.1 - 3.2e-12 46.4 20.8 2.3e-09 37.0 11.3 2.5 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31065.1 - 1.7e-06 27.9 20.3 1.7e-06 27.9 20.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD31065.1 - 0.054 13.2 10.2 0.13 12.0 7.8 2.2 2 0 0 2 2 2 0 Olfactory receptor Carb_anhydrase PF00194.21 PVD31066.1 - 9.7e-69 231.7 0.3 1.2e-63 215.1 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase FAM60A PF15396.6 PVD31066.1 - 0.099 12.6 3.2 0.15 12.0 3.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF1168 PF06658.12 PVD31066.1 - 0.64 9.8 7.9 1.4 8.8 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Syja_N PF02383.18 PVD31067.1 - 4.4e-12 46.0 0.1 4.7e-12 45.9 0.1 1.0 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 PVD31069.1 - 7.7e-11 41.7 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase HSP70 PF00012.20 PVD31070.1 - 4.7e-258 857.3 15.6 6.8e-258 856.8 15.6 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD31070.1 - 5.3e-14 51.8 0.3 3e-11 42.7 0.0 2.4 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 PVD31070.1 - 0.0025 18.2 4.5 3.1 8.3 0.1 4.0 3 2 0 3 3 3 2 Cell division protein FtsA FIVAR PF07554.13 PVD31070.1 - 0.086 13.6 5.5 0.36 11.6 2.2 3.1 2 1 0 2 2 2 0 FIVAR domain Acyltransferase PF01553.21 PVD31071.1 - 8.2e-21 74.0 0.1 1.6e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase His_Phos_1 PF00300.22 PVD31071.1 - 3.8e-15 56.1 0.0 6.7e-09 35.7 0.0 3.1 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) FYVE PF01363.21 PVD31072.1 - 1.2e-11 44.5 13.9 1.2e-11 44.5 13.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger Pex24p PF06398.11 PVD31072.1 - 8.9e-09 34.8 1.8 1.3e-08 34.2 1.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FYVE_2 PF02318.16 PVD31072.1 - 3.9e-05 23.8 5.1 9.6e-05 22.6 5.1 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger DUF639 PF04842.12 PVD31072.1 - 0.00042 19.8 3.2 0.00054 19.4 1.3 1.9 1 1 1 2 2 2 1 Plant protein of unknown function (DUF639) SdpI PF13630.6 PVD31072.1 - 0.24 11.6 3.1 0.55 10.4 3.1 1.6 1 0 0 1 1 1 0 SdpI/YhfL protein family LST1 PF05083.13 PVD31072.1 - 0.55 10.5 3.5 1 9.7 0.4 2.5 2 0 0 2 2 2 0 LST-1 protein Transglut_core PF01841.19 PVD31076.1 - 3.9e-17 62.7 0.0 1.3e-07 32.1 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase-like superfamily Big_3_4 PF13754.6 PVD31076.1 - 0.019 14.7 0.0 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function PPC PF04151.15 PVD31076.1 - 0.076 14.1 1.3 23 6.1 0.1 3.9 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain GDA1_CD39 PF01150.17 PVD31077.1 - 2.5e-110 369.1 0.0 2.7e-98 329.4 0.0 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Baculo_11_kDa PF06143.11 PVD31077.1 - 0.057 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family XhlA PF10779.9 PVD31078.1 - 0.0021 18.2 1.5 0.0054 16.9 0.5 2.2 1 1 1 2 2 2 2 Haemolysin XhlA Dynactin_p22 PF07426.11 PVD31078.1 - 0.0094 15.8 4.8 0.32 10.8 1.3 2.9 2 1 1 3 3 3 2 Dynactin subunit p22 PspA_IM30 PF04012.12 PVD31078.1 - 0.018 14.6 2.4 0.018 14.6 2.4 1.6 1 1 0 1 1 1 0 PspA/IM30 family Sec20 PF03908.13 PVD31078.1 - 0.11 12.5 3.4 0.22 11.5 0.1 2.6 2 1 0 2 2 2 0 Sec20 FapA PF03961.13 PVD31078.1 - 0.12 11.0 3.5 0.12 10.9 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HlyD_2 PF12700.7 PVD31078.1 - 1.9 7.1 8.2 0.8 8.4 5.6 1.5 1 1 1 2 2 2 0 HlyD family secretion protein YabA PF06156.13 PVD31078.1 - 2 9.1 4.9 4.1 8.1 1.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PWWP PF00855.17 PVD31080.1 - 1.3e-29 102.4 9.8 5.5e-16 58.8 0.1 3.3 3 0 0 3 3 3 2 PWWP domain SET PF00856.28 PVD31080.1 - 3.9e-19 69.7 0.1 3.9e-19 69.7 0.1 3.6 5 1 0 5 5 5 1 SET domain AWS PF17907.1 PVD31080.1 - 2.5e-15 56.2 6.2 2.5e-15 56.2 6.2 3.3 4 0 0 4 4 4 1 AWS domain PHD PF00628.29 PVD31080.1 - 3.1e-13 49.4 74.2 0.00037 20.3 11.0 6.6 5 1 1 6 6 6 5 PHD-finger C5HCH PF17982.1 PVD31080.1 - 7.4e-12 45.2 7.5 7.4e-12 45.2 7.5 4.5 5 0 0 5 5 5 1 NSD Cys-His rich domain zf-HC5HC2H PF13771.6 PVD31080.1 - 0.00079 19.6 1.7 0.00079 19.6 1.7 7.7 4 2 3 7 7 7 4 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PVD31080.1 - 0.0013 18.9 1.6 0.0013 18.9 1.6 6.7 4 1 3 7 7 7 3 PHD-zinc-finger like domain HMG_box PF00505.19 PVD31080.1 - 0.0064 16.9 0.1 0.0064 16.9 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box Trypsin_2 PF13365.6 PVD31081.1 - 5.9e-31 108.4 1.2 1.4e-30 107.2 1.2 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PVD31081.1 - 2.1e-12 47.4 0.0 6.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 PVD31081.1 - 9.2e-12 45.1 0.0 3.7e-11 43.2 0.0 2.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD31081.1 - 1.5e-08 34.4 0.0 4.1e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD31081.1 - 3.5e-07 30.5 0.1 8.9e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 PVD31081.1 - 6.3e-07 29.6 0.2 0.17 12.2 0.0 5.4 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Tricorn_PDZ PF14685.6 PVD31081.1 - 0.0006 19.7 0.1 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 PVD31081.1 - 0.037 12.7 0.8 5.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 PVD31081.1 - 0.18 11.0 0.7 13 4.9 0.1 2.2 1 1 1 2 2 2 0 Equine arteritis virus serine endopeptidase S32 PAS_3 PF08447.12 PVD31082.1 - 2.5e-20 72.5 0.0 7.8e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 PVD31082.1 - 5.7e-15 55.4 0.0 1.4e-09 38.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 PVD31082.1 - 5.6e-10 39.2 0.0 0.00075 19.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 PVD31082.1 - 0.00054 20.2 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain AP-5_subunit_s1 PF15001.6 PVD31083.1 - 6.2e-40 137.3 0.0 7.1e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 MCM6_C PF18263.1 PVD31083.1 - 0.0052 17.0 0.1 0.77 10.0 0.3 2.1 2 0 0 2 2 2 2 MCM6 C-terminal winged-helix domain FTA4 PF13093.6 PVD31083.1 - 0.0085 16.0 0.1 0.047 13.6 0.1 1.9 2 0 0 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nop PF01798.18 PVD31085.1 - 4.2e-63 212.9 0.0 4.2e-63 212.9 0.0 3.6 3 1 1 4 4 4 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PVD31085.1 - 5.3e-17 62.0 0.0 4e-16 59.2 0.0 2.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain LptE PF04390.12 PVD31085.1 - 0.095 13.4 0.3 0.5 11.1 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide-assembly DUF4081 PF13312.6 PVD31086.1 - 0.068 13.4 0.4 0.38 11.0 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4081) FAA_hydrolase PF01557.18 PVD31087.1 - 2.2e-70 236.7 0.0 2.6e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_M17 PF00883.21 PVD31088.1 - 3e-65 220.5 0.0 3.9e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain MFS_1 PF07690.16 PVD31089.1 - 7.1e-11 41.6 9.6 7.1e-11 41.6 9.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.8 PVD31089.1 - 4.5 7.6 0.0 4.5 7.6 0.0 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF3007) F-box-like PF12937.7 PVD31090.1 - 2.7e-11 43.2 3.2 3.7e-11 42.7 0.7 2.7 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 PVD31090.1 - 4.1e-08 32.6 4.9 0.011 15.7 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 PVD31090.1 - 3.1e-06 26.9 1.4 2.3e-05 24.2 1.4 2.6 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 PVD31090.1 - 0.001 19.4 13.2 0.82 10.2 0.2 6.6 5 1 3 8 8 8 2 Leucine Rich repeats (2 copies) ASH PF15780.5 PVD31091.1 - 3.4e-10 40.0 11.8 0.0004 20.5 0.7 8.5 9 1 0 9 9 9 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PVD31091.1 - 6.3e-10 39.1 0.1 0.055 13.6 0.0 5.5 5 0 0 5 5 5 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 PVD31091.1 - 2.6e-05 24.0 1.7 26 4.7 0.0 6.7 8 0 0 8 8 8 2 MSP (Major sperm protein) domain DUF11 PF01345.18 PVD31091.1 - 0.036 14.4 1.3 1.9 8.8 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 PrmA PF06325.13 PVD31092.1 - 2.1e-12 47.0 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD31092.1 - 1.5e-10 40.9 0.1 4.4e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 PVD31092.1 - 6.7e-10 38.9 0.0 8.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 PVD31092.1 - 4.5e-09 36.9 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 PVD31092.1 - 1.6e-07 31.0 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 PVD31092.1 - 2.4e-07 30.7 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD31092.1 - 1e-05 26.0 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD31092.1 - 2.3e-05 25.0 0.0 5.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PVD31092.1 - 0.00038 20.2 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 PVD31092.1 - 0.00061 19.1 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 N-6 DNA Methylase Met_10 PF02475.16 PVD31092.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF43 PF01861.16 PVD31092.1 - 0.0021 17.3 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain PCMT PF01135.19 PVD31092.1 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 PVD31092.1 - 0.0055 15.7 0.1 0.0077 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 PVD31092.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6-adenineMlase PF10237.9 PVD31092.1 - 0.04 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_4 PF02390.17 PVD31092.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DNA_methylase PF00145.17 PVD31092.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_5 PF01795.19 PVD31092.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family GTP_EFTU PF00009.27 PVD31093.1 - 1.1e-45 155.6 0.0 1.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 PVD31093.1 - 3.4e-38 131.0 15.0 6e-38 130.2 15.0 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 PVD31093.1 - 8.4e-22 77.0 0.0 2.2e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 PVD31093.1 - 9.7e-18 64.1 0.0 2.2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 PVD31093.1 - 1.2e-13 51.2 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PVD31093.1 - 4.5e-07 29.9 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PVD31093.1 - 0.0022 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 PVD31093.1 - 0.018 15.3 0.0 0.23 11.7 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 PVD31093.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin 7tm_2 PF00002.24 PVD31094.1 - 2.3e-13 50.0 4.9 3e-13 49.6 4.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD31094.1 - 2.6e-13 50.1 2.9 4.3e-13 49.3 2.9 1.3 1 0 0 1 1 1 1 Hormone receptor domain PG_isomerase_N PF18353.1 PVD31094.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.5 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain 7tm_2 PF00002.24 PVD31095.1 - 1.9e-22 79.7 5.4 2.7e-22 79.3 5.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) VirB3 PF05101.13 PVD31095.1 - 0.026 14.8 2.2 0.061 13.6 2.2 1.6 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein FA_desaturase PF00487.24 PVD31096.1 - 1.1e-13 51.7 10.7 1.5e-13 51.2 10.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CLTH PF10607.9 PVD31097.1 - 3.3e-35 121.1 0.2 1e-34 119.6 0.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 PVD31097.1 - 3.5e-06 26.9 0.2 8.7e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 PVD31097.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 PVD31097.1 - 0.0036 17.6 0.4 0.012 15.9 0.4 2.0 1 0 0 1 1 1 1 Ring finger domain DUF2205 PF10224.9 PVD31097.1 - 0.021 14.8 4.9 0.89 9.6 0.0 3.3 2 1 1 3 3 3 0 Short coiled-coil protein zf-RING_5 PF14634.6 PVD31097.1 - 0.063 13.2 0.3 0.21 11.6 0.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF1664 PF07889.12 PVD31097.1 - 0.074 13.1 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UDPGT PF00201.18 PVD31098.1 - 4.2e-05 22.6 0.0 5.1e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF4517 PF15006.6 PVD31099.1 - 8.4e-20 71.5 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) zf-C2H2_4 PF13894.6 PVD31100.1 - 9.7e-15 54.0 63.7 0.033 15.0 0.6 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD31100.1 - 1.2e-10 41.3 77.3 0.058 13.9 1.4 10.0 10 1 0 10 10 10 8 Zinc finger, C2H2 type zf-met PF12874.7 PVD31100.1 - 3.4e-07 30.4 46.2 0.00055 20.2 3.1 7.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD31100.1 - 0.00027 20.9 48.6 0.085 12.9 0.2 8.6 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD31100.1 - 0.0007 19.3 24.5 0.0091 15.7 0.1 5.6 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 PVD31100.1 - 0.0013 19.1 7.4 0.014 15.8 0.4 8.5 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD31100.1 - 0.01 16.1 39.1 0.049 13.9 2.9 7.6 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding DUF3482 PF11981.8 PVD31100.1 - 0.91 8.9 3.6 0.31 10.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) HCO3_cotransp PF00955.21 PVD31101.1 - 7.3e-143 477.0 3.1 9.6e-143 476.7 3.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 PVD31102.1 - 2.9e-70 237.1 0.0 3.9e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain HCO3_cotransp PF00955.21 PVD31102.1 - 1.6e-25 89.9 0.2 1.3e-20 73.7 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family SF3b1 PF08920.10 PVD31104.1 - 6.9e-43 145.9 50.9 2.5e-40 137.6 19.7 5.7 1 1 3 4 4 4 3 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 PVD31104.1 - 3.1e-10 40.4 1.5 0.39 11.3 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 PVD31104.1 - 1.5e-09 37.2 8.1 0.7 10.3 0.1 8.5 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 PVD31104.1 - 3.2e-09 37.0 5.1 0.032 14.6 0.0 7.4 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 PVD31104.1 - 3.5e-06 27.5 1.3 0.67 10.6 0.0 4.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PVD31104.1 - 0.00042 20.4 11.3 1.5 8.9 0.0 6.4 7 2 1 9 9 9 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 PVD31104.1 - 0.0016 18.1 0.8 5.4 6.5 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 PVD31104.1 - 0.0058 16.5 4.4 9.9 6.0 0.2 5.2 3 1 2 5 5 5 1 Domain of unknown function (DUF3385) UME PF08064.13 PVD31104.1 - 0.011 15.6 3.1 3.7 7.5 0.0 5.3 5 2 1 6 6 6 0 UME (NUC010) domain DNA_pol_phi PF04931.13 PVD31104.1 - 0.018 13.2 0.1 2.7 6.0 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi TAF6_C PF07571.13 PVD31104.1 - 0.022 15.0 0.1 1.8 8.9 0.0 3.5 3 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain NUC173 PF08161.12 PVD31104.1 - 0.026 14.2 0.5 6.2 6.4 0.0 4.3 2 2 1 5 5 5 0 NUC173 domain UNC45-central PF11701.8 PVD31104.1 - 0.04 13.9 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF1428 PF07237.11 PVD31104.1 - 0.051 13.8 0.1 0.38 11.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) Dor1 PF04124.12 PVD31104.1 - 0.067 11.9 0.3 2.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Dor1-like family DRIM PF07539.12 PVD31104.1 - 0.071 11.4 0.2 6.4 4.9 0.0 3.2 2 1 1 3 3 3 0 Down-regulated in metastasis DUF4047 PF13256.6 PVD31104.1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) HAGH_C PF16123.5 PVD31105.1 - 2e-29 101.9 0.5 3.1e-29 101.3 0.5 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PVD31105.1 - 2.2e-10 40.9 3.4 1.7e-09 38.0 2.2 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PVD31105.1 - 0.002 17.6 0.1 0.0076 15.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BTB_2 PF02214.22 PVD31106.1 - 3.6e-17 62.5 2.0 3.8e-17 62.4 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain DUF4200 PF13863.6 PVD31106.1 - 0.0063 16.9 8.4 0.0063 16.9 8.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) DUF737 PF05300.11 PVD31106.1 - 0.031 14.6 1.2 0.055 13.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) BTB_3 PF16017.5 PVD31106.1 - 0.096 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF3552 PF12072.8 PVD31106.1 - 0.13 11.7 11.7 0.2 11.0 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Nup54 PF13874.6 PVD31106.1 - 0.81 9.8 5.2 1.6 8.8 5.2 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Exonuc_VII_L PF02601.15 PVD31106.1 - 1.6 8.3 3.7 2.4 7.6 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 PVD31107.1 - 0.18 11.6 5.6 0.25 11.1 5.6 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_LBD PF02931.23 PVD31108.1 - 4.7e-61 206.0 4.4 6.2e-61 205.6 4.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Exo_endo_phos PF03372.23 PVD31108.1 - 0.017 14.6 0.1 0.24 10.9 0.0 2.2 2 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Phage-tail_2 PF09096.10 PVD31109.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 Chal_sti_synt_N PF00195.19 PVD31109.1 - 0.32 10.4 2.4 0.91 8.9 2.4 1.7 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Adaptin_binding PF10199.9 PVD31109.1 - 9 6.9 10.2 1.5e+02 3.0 10.0 3.1 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 zf-B_box PF00643.24 PVD31110.1 - 4e-10 39.7 19.6 2.6e-06 27.5 4.3 2.5 2 0 0 2 2 2 2 B-box zinc finger Tht1 PF04163.12 PVD31110.1 - 0.0015 17.4 0.4 0.0023 16.8 0.4 1.3 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Syntaxin-6_N PF09177.11 PVD31110.1 - 0.0017 18.9 1.3 0.0029 18.1 0.2 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Sec34 PF04136.15 PVD31110.1 - 0.033 14.1 0.6 0.033 14.1 0.6 3.6 2 1 1 4 4 4 0 Sec34-like family DUF3583 PF12126.8 PVD31110.1 - 0.067 12.6 1.5 0.093 12.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF148 PF02520.17 PVD31110.1 - 0.088 12.9 2.3 0.18 11.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 PVD31110.1 - 0.27 11.3 7.6 6 6.9 3.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 PVD31110.1 - 0.29 11.4 1.3 1.1 9.5 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CEBP_ZZ PF16366.5 PVD31110.1 - 0.49 10.7 10.5 0.15 12.3 3.1 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Exonuc_VII_L PF02601.15 PVD31110.1 - 0.58 9.7 3.2 0.84 9.1 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 PVD31110.1 - 0.63 10.3 6.7 2.2 8.5 2.1 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil FlgN PF05130.12 PVD31110.1 - 2 8.9 10.5 2.7 8.5 8.1 2.3 2 1 0 2 2 2 0 FlgN protein zf-HIT PF04438.16 PVD31110.1 - 5.4 7.0 7.1 9.1 6.2 0.3 2.7 2 0 0 2 2 2 0 HIT zinc finger Peptidase_M13 PF01431.21 PVD31116.1 - 2.6e-60 203.5 0.0 5e-60 202.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD31116.1 - 1.3e-19 71.1 0.0 5.2e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M13 NRN1 PF15056.6 PVD31117.1 - 7.2e-05 22.8 0.5 0.059 13.5 0.1 2.6 2 0 0 2 2 2 2 Neuritin protein family DUF19 PF01579.18 PVD31117.1 - 0.00013 21.8 3.4 0.0016 18.2 3.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF19) FlgH PF02107.16 PVD31117.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein DUF19 PF01579.18 PVD31118.1 - 0.00013 21.8 8.4 0.051 13.4 4.1 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF19) SwrA PF17423.2 PVD31118.1 - 0.052 13.5 0.2 0.26 11.3 0.1 2.2 1 1 1 2 2 2 0 Swarming motility protein Glyoxalase PF00903.25 PVD31119.1 - 1.2e-07 32.0 0.1 4.3e-05 23.7 0.1 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PVD31119.1 - 1.6e-07 31.6 0.0 0.00044 20.5 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PVD31119.1 - 0.05 13.7 0.0 6.4 6.9 0.0 2.4 3 0 0 3 3 3 0 Glyoxalase-like domain DUF2353 PF09789.9 PVD31120.1 - 1.2e-08 34.7 2.1 1.2e-08 34.7 2.1 2.8 2 2 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) 7TMR-HDED PF07697.11 PVD31120.1 - 7.1 6.7 11.2 1.2 9.2 4.9 2.2 2 0 0 2 2 2 0 7TM-HD extracellular Reeler PF02014.16 PVD31122.1 - 4.3e-16 59.8 1.1 4.3e-16 59.8 1.1 1.7 2 0 0 2 2 2 1 Reeler domain DOMON PF03351.17 PVD31122.1 - 1.7e-15 57.4 0.8 2.4e-15 56.9 0.1 1.6 2 0 0 2 2 2 1 DOMON domain Avidin PF01382.17 PVD31122.1 - 0.12 12.9 0.5 0.26 11.8 0.5 1.6 1 0 0 1 1 1 0 Avidin family Reeler PF02014.16 PVD31123.1 - 4.2e-16 59.9 1.4 1.4e-15 58.2 0.2 2.1 2 0 0 2 2 2 1 Reeler domain DOMON PF03351.17 PVD31123.1 - 2.6e-15 56.7 0.2 5.3e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 DOMON domain Gal-3-0_sulfotr PF06990.11 PVD31124.1 - 1.3e-53 182.4 6.8 1.7e-53 182.0 6.8 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD31124.1 - 5.2e-06 26.6 1.9 7.3e-05 22.8 1.9 2.2 1 1 0 1 1 1 1 Sulfotransferase family LapA_dom PF06305.11 PVD31125.1 - 0.085 12.7 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GSG-1 PF07803.11 PVD31125.1 - 0.086 12.8 0.1 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 GSG1-like protein DUF4448 PF14610.6 PVD31125.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Man-6-P_recep PF02157.15 PVD31126.1 - 1.4e-15 57.1 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 PVD31126.1 - 3.7e-15 56.5 0.0 4.8e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 RCR PF12273.8 PVD31126.1 - 0.047 14.3 0.7 0.11 13.1 0.7 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3556 PF12077.8 PVD31126.1 - 0.093 11.1 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Tetraspanin PF00335.20 PVD31127.1 - 2.9e-08 33.7 15.4 7.3e-08 32.4 2.2 2.1 1 1 1 2 2 2 2 Tetraspanin family Phage_holin_3_6 PF07332.11 PVD31127.1 - 1.9 8.5 5.4 0.23 11.5 1.2 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TarH PF02203.15 PVD31127.1 - 2.2 8.1 3.6 3.7 7.4 3.6 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Man-6-P_recep PF02157.15 PVD31128.1 - 9.7e-91 303.3 16.2 8.1e-13 48.0 0.5 7.3 6 1 1 7 7 7 7 Mannose-6-phosphate receptor ATG27 PF09451.10 PVD31128.1 - 3.8e-64 217.1 8.5 6.4e-09 36.0 0.0 7.8 5 2 2 7 7 7 7 Autophagy-related protein 27 S1FA PF04689.13 PVD31128.1 - 0.001 19.2 39.4 0.24 11.5 0.8 7.1 7 0 0 7 7 7 4 DNA binding protein S1FA Pcc1 PF09341.10 PVD31128.1 - 0.086 13.0 0.1 13 6.0 0.1 3.0 2 0 0 2 2 2 0 Transcription factor Pcc1 Podoplanin PF05808.11 PVD31128.1 - 0.15 12.2 29.9 4.4 7.4 0.5 6.8 7 0 0 7 7 7 0 Podoplanin Kelch_1 PF01344.25 PVD31129.1 - 4.3e-17 61.4 13.3 3.9e-10 39.1 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 PVD31129.1 - 8.2e-06 25.9 6.8 0.13 12.6 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 PVD31129.1 - 2.8e-05 23.9 2.6 0.081 12.9 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 PVD31129.1 - 0.029 14.4 3.7 0.074 13.1 0.1 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD31129.1 - 0.062 13.3 2.8 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 PVD31130.1 - 2e-77 254.6 13.1 8.7e-15 54.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD31130.1 - 3.9e-46 153.9 7.1 9.3e-13 48.0 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD31130.1 - 7.6e-31 104.9 1.4 8e-08 32.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PVD31130.1 - 3.4e-26 91.0 7.8 4e-05 23.8 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD31130.1 - 3.6e-22 78.1 4.6 0.00079 19.4 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD31130.1 - 9.2e-18 63.8 7.9 4e-06 26.7 0.3 6.4 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 PVD31130.1 - 2.2e-08 34.1 0.1 3.7e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 PVD31131.1 - 3.7e-27 94.8 0.0 6e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD31131.1 - 4.1e-08 33.2 0.6 1.1e-07 31.9 0.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch TGFb_propeptide PF00688.18 PVD31133.1 - 2.5e-06 27.4 0.1 4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 TGF-beta propeptide Glycos_transf_2 PF00535.26 PVD31134.1 - 9.4e-16 58.1 0.0 2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD31134.1 - 6e-13 49.2 0.9 1e-12 48.4 0.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 PVD31134.1 - 6e-05 23.7 0.0 0.29 11.9 0.0 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 PVD31134.1 - 0.042 13.5 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 PVD31134.1 - 0.11 12.0 0.2 1.4 8.5 0.1 2.2 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Glycos_transf_2 PF00535.26 PVD31135.1 - 3.1e-26 92.2 0.0 5.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD31135.1 - 9.9e-15 54.9 2.2 1.5e-14 54.4 2.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PVD31135.1 - 2.7e-06 26.9 0.1 6.2e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PVD31135.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 PVD31135.1 - 0.0034 18.1 0.2 0.23 12.2 0.1 2.4 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like UL45 PF05473.12 PVD31135.1 - 0.012 15.3 0.4 0.047 13.3 0.1 2.1 2 1 1 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Glyco_tranf_2_2 PF10111.9 PVD31135.1 - 0.083 12.3 0.2 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 AD PF09793.9 PVD31136.1 - 5.1e-24 84.2 0.4 8.4e-24 83.5 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 PVD31136.1 - 0.008 15.7 1.5 0.096 12.2 1.5 2.0 1 1 0 1 1 1 1 Gemin6 protein CzcE PF16986.5 PVD31136.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE DHR10 PF18595.1 PVD31137.1 - 0.0071 16.4 1.7 0.0097 16.0 1.7 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF3804 PF12707.7 PVD31137.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) TEX12 PF15219.6 PVD31137.1 - 0.056 13.8 1.1 0.12 12.7 1.1 1.6 1 1 0 1 1 1 0 Testis-expressed 12 RNA_pol_Rpb2_6 PF00562.28 PVD31138.1 - 1e-116 390.2 0.0 3.3e-116 388.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PVD31138.1 - 9.6e-39 133.0 0.1 1.3e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 PVD31138.1 - 3.1e-28 97.7 0.0 6.6e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PVD31138.1 - 1.1e-19 70.6 0.0 2.7e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 PVD31138.1 - 2.2e-19 69.2 0.0 8.6e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 PVD31138.1 - 3.6e-08 33.3 0.0 6.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 C1q PF00386.21 PVD31140.1 - 3e-15 56.6 0.5 3.9e-15 56.2 0.5 1.2 1 0 0 1 1 1 1 C1q domain EspB_PE PF18625.1 PVD31140.1 - 0.11 13.0 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain MFS_1 PF07690.16 PVD31141.1 - 2.2e-51 174.8 35.4 1.4e-48 165.6 33.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Guanylate_cyc PF00211.20 PVD31142.1 - 1.1e-38 132.8 0.1 1.6e-38 132.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 PVD31143.1 - 1.7e-65 220.1 0.1 1.6e-60 203.8 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 PVD31143.1 - 2.9e-05 24.5 0.1 5.2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) AC_N PF16214.5 PVD31143.1 - 3.7e-05 23.0 0.0 3.7e-05 23.0 0.0 2.8 4 0 0 4 4 4 1 Adenylyl cyclase N-terminal extracellular and transmembrane region TBK1_ULD PF18396.1 PVD31143.1 - 0.13 12.2 0.1 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain DUF2374 PF09574.10 PVD31143.1 - 4.4 7.2 7.2 2.4 8.0 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Dendrin PF15498.6 PVD31144.1 - 0.043 12.6 0.0 0.052 12.3 0.0 1.0 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin AC_N PF16214.5 PVD31145.1 - 5.4e-09 35.7 1.4 5.4e-09 35.7 1.4 2.1 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region Yae1_N PF09811.9 PVD31146.1 - 1.1e-10 41.0 0.3 1.8e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Sbi-IV PF11621.8 PVD31146.1 - 0.04 14.3 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI RBD PF02196.15 PVD31148.1 - 1.4e-05 25.1 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 PVD31148.1 - 0.00018 21.7 0.1 0.00038 20.6 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain Cobl PF09469.10 PVD31148.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain Ig_3 PF13927.6 PVD31149.1 - 2.6e-09 37.5 2.5 3.8e-05 24.2 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD31149.1 - 1.4e-05 25.2 1.8 4.4e-05 23.6 0.2 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD31149.1 - 0.00067 19.9 8.8 2.5 8.5 2.3 4.2 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD31149.1 - 0.0076 16.4 1.7 0.02 15.0 0.4 2.3 2 1 0 2 2 2 1 Immunoglobulin domain Lep_receptor_Ig PF06328.11 PVD31149.1 - 0.026 14.5 0.8 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 Ig-like C2-type domain IgGFc_binding PF17517.2 PVD31149.1 - 0.035 13.4 0.2 0.054 12.8 0.2 1.3 1 0 0 1 1 1 0 IgGFc binding protein Ribophorin_I PF04597.14 PVD31149.1 - 0.044 13.0 0.9 0.053 12.7 0.0 1.5 2 0 0 2 2 2 0 Ribophorin I ig PF00047.25 PVD31150.1 - 9.2e-09 35.4 0.4 0.00015 21.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 PVD31150.1 - 2e-07 31.5 0.2 0.0091 16.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD31150.1 - 0.00078 19.6 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD31150.1 - 0.0048 16.9 0.2 3.9 7.6 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 PVD31150.1 - 0.023 15.0 1.0 9.4 6.6 0.1 3.6 2 1 1 3 3 3 0 Immunoglobulin domain C1-set PF07654.15 PVD31150.1 - 0.024 15.0 1.5 4 7.9 0.0 3.6 3 1 0 3 3 3 0 Immunoglobulin C1-set domain I-set PF07679.16 PVD31150.1 - 0.035 14.2 0.0 0.3 11.2 0.0 2.5 3 1 0 3 3 3 0 Immunoglobulin I-set domain PilN PF05137.13 PVD31150.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) DUF1682 PF07946.14 PVD31151.1 - 9.5e-50 169.6 7.4 9.5e-50 169.6 7.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Ig_3 PF13927.6 PVD31152.1 - 0.0003 21.3 0.6 0.45 11.1 0.0 3.4 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD31152.1 - 0.0031 17.5 0.5 0.16 12.1 0.2 3.2 3 1 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD31152.1 - 0.0079 16.5 0.3 5.4 7.4 0.2 3.9 3 2 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 PVD31152.1 - 0.031 14.4 0.0 0.75 10.0 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin V-set domain BIR PF00653.21 PVD31155.1 - 7.6e-29 100.2 19.6 5.9e-18 65.3 0.1 4.2 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 PVD31155.1 - 1.3e-10 40.9 7.5 1.3e-10 40.9 7.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD31155.1 - 6.6e-06 25.9 8.4 6.6e-06 25.9 8.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 PVD31155.1 - 0.7 9.9 10.8 1.7 8.7 0.0 3.4 3 1 0 3 3 3 0 C3HC zinc finger-like DUF3099 PF11298.8 PVD31156.1 - 0.94 9.7 3.5 32 4.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Nse4_C PF08743.10 PVD31157.1 - 5.4e-31 106.7 0.1 1.2e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 PVD31157.1 - 6.7e-07 29.3 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE XH PF03469.14 PVD31157.1 - 0.065 13.1 0.6 0.14 12.0 0.6 1.6 1 0 0 1 1 1 0 XH domain PTS_2-RNA PF01885.16 PVD31157.1 - 0.068 13.2 0.2 0.16 12.0 0.2 1.5 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Arg_decarbox_C PF17944.1 PVD31157.1 - 0.18 12.4 0.4 2.2 8.9 0.0 2.9 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension p450 PF00067.22 PVD31158.1 - 1.4e-54 185.6 0.0 1.7e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_B562 PF07361.11 PVD31158.1 - 0.16 12.7 0.1 2.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b562 7tm_2 PF00002.24 PVD31159.1 - 3.4e-39 134.6 12.4 5.4e-24 84.8 1.9 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD31159.1 - 2.6e-16 59.7 5.8 4.6e-16 58.9 5.8 1.4 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 PVD31160.1 - 2.3e-26 92.6 7.4 3.5e-26 92.0 7.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 PVD31160.1 - 0.0017 18.6 0.1 0.0031 17.8 0.1 1.4 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 PVD31161.1 - 3.1e-06 26.7 0.2 4.3e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Glyco_hydro_1 PF00232.18 PVD31162.1 - 0 1785.7 32.3 8.1e-174 578.3 4.8 6.0 4 2 2 6 6 6 6 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 PVD31162.1 - 9.9e-10 39.1 0.8 1.2 9.5 0.0 6.3 7 0 0 7 7 7 3 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.18 PVD31162.1 - 0.0012 18.3 14.6 1.2 8.5 0.1 5.1 4 1 0 4 4 4 3 Cellulase (glycosyl hydrolase family 5) DUF3258 PF11646.8 PVD31162.1 - 0.0041 17.2 0.1 2.5 8.3 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function DUF3258 SAM_Exu PF18609.1 PVD31162.1 - 0.042 13.9 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Exuperantia SAM-like domain LPD16 PF18830.1 PVD31162.1 - 0.9 9.5 4.0 17 5.5 0.0 3.2 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 16 Glyco_hydro_1 PF00232.18 PVD31163.1 - 2.3e-30 105.4 0.1 2.6e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 PVD31163.1 - 0.0037 16.7 0.0 0.0037 16.7 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2326 PF10088.9 PVD31163.1 - 0.029 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) DUF3258 PF11646.8 PVD31163.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Glyco_hydro_1 PF00232.18 PVD31164.1 - 0 1903.3 24.3 8e-155 515.7 2.5 5.0 4 1 1 5 5 5 5 Glycosyl hydrolase family 1 Cellulase PF00150.18 PVD31164.1 - 5.4e-11 42.5 5.4 0.13 11.7 0.0 7.2 8 0 0 8 8 8 4 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 PVD31164.1 - 0.0018 17.8 0.0 15 5.1 0.0 4.2 4 0 0 4 4 4 2 Glycosyl hydrolase catalytic core KSHV_K1 PF11049.8 PVD31164.1 - 0.05 13.5 1.6 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Glycos_transf_2 PF00535.26 PVD31164.1 - 0.073 12.9 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 Lactamase_B_2 PF12706.7 PVD31165.1 - 1.9e-05 24.3 0.2 0.00011 21.8 0.2 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BppU_IgG PF18667.1 PVD31165.1 - 0.092 12.9 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Baseplate upper protein immunoglobulin like domain Lactamase_B PF00753.27 PVD31165.1 - 0.1 12.6 1.9 0.15 12.1 0.9 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily WD40 PF00400.32 PVD31166.1 - 6.8e-21 74.2 0.7 8.3e-07 29.6 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD31166.1 - 1.5e-06 28.4 0.0 0.0053 17.0 0.0 3.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD31166.1 - 0.00064 19.7 0.2 0.069 13.0 0.0 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rhomboid_SP PF12595.8 PVD31166.1 - 0.19 11.0 0.6 0.41 10.0 0.6 1.4 1 0 0 1 1 1 0 Rhomboid serine protease FtsX_ECD PF18075.1 PVD31166.1 - 0.33 11.6 5.8 0.97 10.1 4.8 2.1 2 0 0 2 2 2 0 FtsX extracellular domain RabGAP-TBC PF00566.18 PVD31167.1 - 4.2e-57 193.3 0.1 6.5e-57 192.6 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LsmAD PF06741.13 PVD31168.1 - 3.2e-19 69.2 5.1 3.2e-19 69.2 5.1 2.0 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.15 PVD31168.1 - 0.001 18.6 0.7 0.001 18.6 0.7 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region TPR_12 PF13424.6 PVD31169.1 - 4.4e-108 353.7 104.4 3.8e-15 55.9 1.5 17.1 14 1 6 20 20 20 14 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31169.1 - 1.3e-100 322.3 65.0 7.2e-06 25.7 0.1 24.7 26 0 0 26 26 24 22 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31169.1 - 2.1e-91 296.3 69.1 5e-05 22.9 0.0 25.2 27 0 0 27 27 26 21 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31169.1 - 1.1e-63 206.1 49.8 9.7e-05 22.3 0.5 24.7 25 0 0 25 25 25 13 Tetratricopeptide repeat CHAT PF12770.7 PVD31169.1 - 8.2e-61 205.9 0.5 1.8e-60 204.8 0.5 1.6 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 PVD31169.1 - 6.3e-60 194.5 80.7 0.001 19.0 0.1 27.0 28 0 0 28 28 27 18 Tetratricopeptide repeat TPR_10 PF13374.6 PVD31169.1 - 1e-54 181.0 66.4 0.00019 21.2 0.0 22.8 24 0 0 24 24 22 13 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD31169.1 - 1.1e-20 74.3 75.5 4.1e-10 39.6 1.4 8.7 3 1 5 8 8 8 7 MalT-like TPR region TPR_11 PF13414.6 PVD31169.1 - 5.4e-16 58.0 30.0 2.2e-05 24.1 0.1 17.2 20 3 2 22 22 22 3 TPR repeat Rapsyn_N PF10579.9 PVD31169.1 - 1.1e-15 57.4 24.4 0.13 12.3 0.1 12.4 10 3 2 13 13 12 5 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 PVD31169.1 - 1.3e-15 56.3 40.3 1 10.2 0.1 17.1 17 0 0 17 17 16 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD31169.1 - 3.6e-13 49.1 52.9 0.82 10.7 0.8 20.4 19 4 3 23 23 21 4 Tetratricopeptide repeat RPN7 PF10602.9 PVD31169.1 - 8.5e-08 32.1 16.3 0.11 12.2 0.1 8.3 3 2 7 10 10 10 3 26S proteasome subunit RPN7 TPR_17 PF13431.6 PVD31169.1 - 5.1e-07 29.6 43.4 0.0099 16.2 0.2 15.5 17 0 0 17 17 15 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD31169.1 - 1.2e-05 25.9 64.0 0.0038 17.8 0.3 15.5 13 4 3 16 16 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31169.1 - 0.00023 21.6 71.6 0.016 15.7 0.2 14.8 12 5 6 19 19 17 4 Tetratricopeptide repeat PPR PF01535.20 PVD31169.1 - 0.00028 20.9 6.9 26 5.4 0.0 8.1 7 0 0 7 7 7 0 PPR repeat TPR_6 PF13174.6 PVD31169.1 - 0.011 16.3 37.6 50 4.8 0.0 16.7 21 0 0 21 21 18 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD31169.1 - 0.027 14.6 45.2 3.2 8.0 0.0 14.2 10 5 6 17 17 16 0 Tetratricopeptide repeat MIT PF04212.18 PVD31169.1 - 0.091 12.8 17.5 3.3 7.8 0.0 8.2 8 1 1 9 9 9 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.12 PVD31169.1 - 0.15 12.0 5.7 0.39 10.7 0.4 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF627) ANAPC5 PF12862.7 PVD31169.1 - 0.41 10.7 38.8 1.3 9.1 0.0 10.8 11 4 1 12 12 10 0 Anaphase-promoting complex subunit 5 CN_hydrolase PF00795.22 PVD31170.1 - 8.2e-48 163.0 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AP_endonuc_2 PF01261.24 PVD31170.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PP2C PF00481.21 PVD31171.1 - 4.5e-61 206.7 0.0 8.5e-61 205.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PVD31171.1 - 0.0071 16.0 0.0 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C SUIM_assoc PF16619.5 PVD31171.1 - 0.64 10.1 2.7 0.53 10.4 0.1 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_3 PF13606.6 PVD31172.1 - 2.3e-07 30.5 3.1 0.59 10.9 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 PVD31172.1 - 2.7e-07 31.1 2.3 0.0062 17.1 0.2 4.0 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD31172.1 - 0.0002 21.9 0.6 4.7 7.9 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD31172.1 - 0.014 15.7 0.7 3.4 8.1 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 PVD31172.1 - 1 9.9 8.3 59 4.4 0.1 4.9 6 0 0 6 6 6 0 Ankyrin repeat CCDC74_C PF14917.6 PVD31173.1 - 2e-37 128.4 2.0 2e-37 128.4 2.0 2.7 2 1 1 3 3 3 1 Coiled coil protein 74, C terminal CCDC92 PF14916.6 PVD31173.1 - 1.8e-22 78.8 1.5 1.8e-22 78.8 1.5 2.8 3 0 0 3 3 3 1 Coiled-coil domain of unknown function PTPlike_phytase PF14566.6 PVD31173.1 - 0.0086 16.2 0.0 0.0086 16.2 0.0 2.5 2 1 0 2 2 2 1 Inositol hexakisphosphate bZIP_1 PF00170.21 PVD31173.1 - 0.02 15.0 7.0 0.91 9.7 0.1 4.1 3 1 0 3 3 3 0 bZIP transcription factor WD40_alt PF14077.6 PVD31173.1 - 0.02 14.7 2.8 0.26 11.2 0.0 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif betaPIX_CC PF16523.5 PVD31173.1 - 0.066 13.0 0.6 0.066 13.0 0.6 3.6 4 1 0 4 4 4 0 betaPIX coiled coil DivIC PF04977.15 PVD31173.1 - 0.19 11.5 11.5 6.4 6.6 0.1 3.8 3 0 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 PVD31173.1 - 0.62 7.9 9.9 0.83 7.5 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT_CC PF16559.5 PVD31173.1 - 0.63 10.0 10.1 2.2 8.2 0.2 3.5 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KLRAQ PF10205.9 PVD31173.1 - 0.82 9.9 12.0 2.5 8.4 1.7 3.2 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein SlyX PF04102.12 PVD31173.1 - 1.6 9.4 19.3 22 5.7 1.4 4.8 3 1 1 4 4 4 0 SlyX VPS11_C PF12451.8 PVD31173.1 - 5.7 7.3 6.9 0.53 10.6 1.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Fib_alpha PF08702.10 PVD31173.1 - 6.1 7.0 14.6 6.4 7.0 6.7 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Uds1 PF15456.6 PVD31173.1 - 8.3 6.6 16.5 1.1 9.4 9.7 3.0 2 2 0 2 2 2 0 Up-regulated During Septation Rep_fac_C PF08542.11 PVD31174.1 - 1.7e-26 92.5 0.0 4.3e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 PVD31174.1 - 1.6e-12 48.0 0.1 3.6e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PVD31174.1 - 3.5e-12 46.4 0.0 9.9e-11 41.7 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 PVD31174.1 - 4.5e-06 26.7 0.0 9.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD31174.1 - 1.7e-05 25.3 0.1 0.0012 19.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 PVD31174.1 - 3.8e-05 23.5 0.0 8.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD31174.1 - 4.6e-05 23.7 0.1 0.088 13.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PVD31174.1 - 4.6e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 PVD31174.1 - 5.4e-05 22.7 0.0 0.00078 18.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 PVD31174.1 - 6.7e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 PVD31174.1 - 7.9e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD31174.1 - 0.00029 21.2 0.2 0.00095 19.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 PVD31174.1 - 0.00042 20.6 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 PVD31174.1 - 0.0009 19.0 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 PVD31174.1 - 0.0019 17.8 0.1 0.0069 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD31174.1 - 0.0022 18.5 0.1 0.009 16.6 0.0 1.9 1 1 0 2 2 2 1 AAA domain TniB PF05621.11 PVD31174.1 - 0.0023 17.4 0.1 2.1 7.7 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein AAA_5 PF07728.14 PVD31174.1 - 0.0035 17.3 0.2 0.015 15.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PVD31174.1 - 0.0039 16.9 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 PVD31174.1 - 0.004 16.9 0.5 0.51 10.1 0.0 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase MipZ PF09140.11 PVD31174.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_3 PF07726.11 PVD31174.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PVD31174.1 - 0.041 14.3 0.1 0.28 11.6 0.0 2.4 2 1 0 2 2 1 0 RNA helicase DUF4597 PF15366.6 PVD31174.1 - 0.042 13.6 0.5 12 5.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) NTPase_1 PF03266.15 PVD31174.1 - 0.048 13.6 0.4 0.2 11.6 0.1 2.1 1 1 0 2 2 2 0 NTPase DUF815 PF05673.13 PVD31174.1 - 0.048 12.8 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MeaB PF03308.16 PVD31174.1 - 0.052 12.5 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 PVD31174.1 - 0.059 13.6 0.3 0.16 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 PVD31174.1 - 0.064 12.5 0.6 1.5 8.0 0.6 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 PVD31174.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DNA_pol3_delta PF06144.13 PVD31174.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CBM_14 PF01607.24 PVD31175.1 - 3.7e-55 183.9 59.0 5.4e-12 45.7 4.2 5.3 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD31176.1 - 3.3e-08 33.6 3.2 6.2e-08 32.7 3.2 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD31177.1 - 3.4e-14 52.7 2.2 5.5e-14 52.1 2.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain VKOR PF07884.14 PVD31178.1 - 1.2e-14 54.5 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family IU_nuc_hydro PF01156.19 PVD31179.1 - 1.3e-67 228.5 0.1 1.7e-67 228.2 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Clathrin_propel PF01394.20 PVD31180.1 - 3.1e-07 30.4 0.1 0.075 13.4 0.0 4.8 5 0 0 5 5 5 3 Clathrin propeller repeat ketoacyl-synt PF00109.26 PVD31181.1 - 4.1e-84 282.1 0.0 2e-83 279.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PVD31181.1 - 2.7e-50 170.8 0.4 6.7e-50 169.5 0.4 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 PVD31181.1 - 2.2e-45 155.5 0.1 3.9e-45 154.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 PVD31181.1 - 7.1e-38 130.5 0.3 1.4e-37 129.6 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 PVD31181.1 - 6.1e-35 119.8 0.1 1.5e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 PVD31181.1 - 9.1e-15 55.1 0.0 2.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 PVD31181.1 - 1.3e-09 38.3 0.2 4.3e-09 36.6 0.2 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD31181.1 - 2.9e-08 33.4 0.1 6.2e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Condensation PF00668.20 PVD31181.1 - 3.7e-08 32.5 0.0 9.8e-08 31.1 0.0 1.6 2 0 0 2 2 2 1 Condensation domain Thiolase_N PF00108.23 PVD31181.1 - 4.1e-06 26.4 0.1 8.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 PVD31181.1 - 1.9e-05 24.4 0.1 4.3e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Drf_FH1 PF06346.12 PVD31182.1 - 0.23 11.2 15.8 0.78 9.5 3.5 2.2 2 0 0 2 2 2 0 Formin Homology Region 1 YqzE PF14038.6 PVD31183.1 - 0.64 10.1 3.5 75 3.4 0.1 3.4 2 1 1 3 3 3 0 YqzE-like protein Ion_trans PF00520.31 PVD31185.1 - 7.8e-38 130.1 14.0 1.2e-37 129.5 14.0 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD31185.1 - 7.1e-25 87.2 0.4 1.8e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD31185.1 - 2.4e-11 43.4 9.5 2.4e-11 43.4 9.5 2.1 2 0 0 2 2 2 1 Ion channel SOG2 PF10428.9 PVD31186.1 - 7.5 5.6 31.7 11 5.1 31.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 PVD31187.1 - 1.6e-14 53.6 28.4 5e-10 38.8 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bcl-2 PF00452.19 PVD31187.1 - 0.095 13.4 0.1 0.32 11.7 0.1 1.9 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DIL PF01843.19 PVD31188.1 - 0.069 13.4 0.5 1.7 8.9 0.1 2.8 3 0 0 3 3 3 0 DIL domain Fringe PF02434.16 PVD31189.1 - 1.8e-54 184.8 0.0 3e-45 154.6 0.0 2.1 2 0 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 PVD31189.1 - 0.0029 17.4 0.0 13 5.6 0.0 3.3 2 1 1 3 3 3 2 Galactosyltransferase Glycos_transf_2 PF00535.26 PVD31189.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 2OG-FeII_Oxy_2 PF13532.6 PVD31190.1 - 1.5e-21 77.5 0.0 5.3e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DTC PF18102.1 PVD31191.1 - 2.1e-53 180.0 0.0 5.3e-53 178.7 0.0 1.7 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 PVD31191.1 - 6.8e-34 116.3 2.3 1.3e-15 57.8 0.0 2.5 2 0 0 2 2 2 2 WWE domain zf-RING_2 PF13639.6 PVD31191.1 - 0.00024 21.4 8.5 0.00048 20.4 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD31191.1 - 0.0015 18.4 9.8 0.0026 17.6 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD31191.1 - 0.0016 18.4 6.1 0.0036 17.3 6.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD31191.1 - 0.021 15.1 7.1 0.048 14.0 7.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF2403 PF10290.9 PVD31191.1 - 0.086 13.3 0.2 0.29 11.6 0.2 1.8 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) zf-C3HC4_2 PF13923.6 PVD31191.1 - 4 7.4 10.2 0.27 11.1 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 PVD31191.1 - 9.4 6.3 10.4 6.1 6.8 0.6 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Lebercilin PF15619.6 PVD31192.1 - 0.00024 20.8 12.5 0.00034 20.3 12.5 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease VPS38 PF17649.1 PVD31192.1 - 0.0038 16.2 3.7 0.0051 15.7 3.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 IFT57 PF10498.9 PVD31192.1 - 0.0049 15.9 11.8 0.007 15.4 11.8 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tektin PF03148.14 PVD31192.1 - 0.0069 15.2 11.4 0.0094 14.7 11.4 1.1 1 0 0 1 1 1 1 Tektin family Atg14 PF10186.9 PVD31192.1 - 0.045 12.8 5.5 0.055 12.6 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 PVD31192.1 - 0.049 12.5 13.7 0.071 12.0 13.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 PVD31192.1 - 0.05 13.1 10.9 0.07 12.6 10.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 PVD31192.1 - 0.052 12.9 11.1 0.079 12.3 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.14 PVD31192.1 - 0.055 13.8 7.1 0.084 13.2 7.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Filament PF00038.21 PVD31192.1 - 0.091 12.3 12.5 0.18 11.4 12.5 1.4 1 1 0 1 1 1 0 Intermediate filament protein YlqD PF11068.8 PVD31192.1 - 0.1 13.0 11.9 0.18 12.2 11.9 1.4 1 0 0 1 1 1 0 YlqD protein Spc7 PF08317.11 PVD31192.1 - 0.11 11.4 13.8 0.15 10.9 13.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 PVD31192.1 - 0.11 12.6 8.0 0.18 11.8 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 PVD31192.1 - 0.11 11.5 8.4 0.15 11.1 8.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1043 PF06295.12 PVD31192.1 - 0.16 11.9 7.0 0.26 11.3 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) USP8_interact PF08941.10 PVD31192.1 - 0.22 11.3 3.6 0.36 10.6 3.6 1.5 1 0 0 1 1 1 0 USP8 interacting DUF641 PF04859.12 PVD31192.1 - 0.28 11.5 12.3 1.9 8.9 12.3 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Phlebovirus_NSM PF07246.11 PVD31192.1 - 0.34 10.2 6.7 0.45 9.8 6.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMPIT PF07851.13 PVD31192.1 - 0.39 9.9 8.6 0.51 9.5 8.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 PVD31192.1 - 0.4 9.5 3.6 0.5 9.2 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 PVD31192.1 - 0.44 9.1 7.3 0.57 8.7 7.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 PVD31192.1 - 0.45 10.5 12.2 0.17 11.9 8.8 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 PVD31192.1 - 0.48 11.2 5.0 0.84 10.4 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Lipoprotein_7 PF01540.16 PVD31192.1 - 0.6 9.4 5.4 0.74 9.0 5.4 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein FAM76 PF16046.5 PVD31192.1 - 0.65 9.3 6.2 0.98 8.7 6.2 1.2 1 0 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 PVD31192.1 - 0.79 9.9 18.1 2.4 8.3 18.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 PVD31192.1 - 0.83 10.1 14.1 2 8.8 14.1 1.6 1 1 0 1 1 1 0 Fez1 zf-C4H2 PF10146.9 PVD31192.1 - 0.97 9.7 12.5 1.4 9.1 12.5 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF948 PF06103.11 PVD31192.1 - 1.7 8.9 6.6 1.6 9.0 1.8 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 PVD31192.1 - 3 8.0 11.6 4.5 7.4 11.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 PVD31192.1 - 3.8 5.4 7.6 4.3 5.2 7.6 1.0 1 0 0 1 1 1 0 Prominin OEP PF02321.18 PVD31192.1 - 4.2 7.1 12.3 6.1 6.6 12.3 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein HemX PF04375.14 PVD31192.1 - 5.4 6.2 14.6 7.5 5.7 14.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_II PF06009.12 PVD31192.1 - 5.8 6.9 13.3 15 5.6 13.3 1.6 1 1 0 1 1 1 0 Laminin Domain II UPF0242 PF06785.11 PVD31192.1 - 6.2 6.9 16.7 11 6.1 16.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 PVD31192.1 - 8.6 6.4 17.3 17 5.5 16.8 1.8 1 1 0 1 1 1 0 FlxA-like protein Tim17 PF02466.19 PVD31193.1 - 1.5e-25 89.7 7.8 1.9e-25 89.4 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 PVD31193.1 - 0.021 14.6 3.7 2 8.2 4.4 2.4 2 1 0 2 2 2 0 YMGG-like Gly-zipper Romo1 PF10247.9 PVD31193.1 - 2.2 8.7 18.9 0.46 10.9 4.9 2.9 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 FAM101 PF15068.6 PVD31194.1 - 1.9e-12 47.6 2.4 2.5e-12 47.2 2.4 1.1 1 0 0 1 1 1 1 FAM101 family SNF PF00209.18 PVD31196.1 - 1.3e-38 133.0 7.4 2.4e-38 132.1 7.4 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family YrvL PF14184.6 PVD31196.1 - 0.059 13.5 5.5 0.033 14.3 2.8 1.7 2 0 0 2 2 2 0 Regulatory protein YrvL DUF3767 PF12597.8 PVD31196.1 - 0.072 12.9 1.4 0.1 12.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) SNF PF00209.18 PVD31197.1 - 1.5e-78 264.8 11.1 1.8e-78 264.5 11.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3432 PF11914.8 PVD31198.1 - 0.013 15.7 15.7 0.08 13.2 11.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Alpha-amylase_C PF02806.18 PVD31199.1 - 0.11 12.9 2.1 32 5.1 1.6 3.3 1 1 1 2 2 2 0 Alpha amylase, C-terminal all-beta domain I-set PF07679.16 PVD31200.1 - 4.6e-40 135.6 0.0 1.1e-18 67.0 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD31200.1 - 1.5e-31 108.8 0.1 4e-14 53.0 0.0 3.0 3 0 0 3 3 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD31200.1 - 3.7e-24 84.8 0.2 1.8e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain CH PF00307.31 PVD31200.1 - 6.7e-23 81.0 0.1 1.5e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain ig PF00047.25 PVD31200.1 - 6.7e-19 67.9 0.1 1.3e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Smoothelin PF12510.8 PVD31200.1 - 7.6e-12 45.1 1.3 1.8e-11 43.9 1.3 1.6 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein V-set PF07686.17 PVD31200.1 - 5.3e-09 36.2 2.5 0.016 15.4 0.0 4.9 2 2 2 4 4 4 2 Immunoglobulin V-set domain CAMSAP_CH PF11971.8 PVD31200.1 - 7e-07 29.0 0.1 4.3e-06 26.5 0.1 2.2 3 0 0 3 3 3 1 CAMSAP CH domain C2-set_2 PF08205.12 PVD31200.1 - 0.00012 22.0 3.0 0.083 13.0 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD31200.1 - 0.0019 18.5 0.3 1 9.8 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 PVD31200.1 - 0.0021 17.6 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain GTP1_OBG PF01018.22 PVD31200.1 - 0.09 12.4 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 GTP1/OBG YqaJ PF09588.10 PVD31200.1 - 0.16 12.1 3.6 0.37 10.9 3.6 1.5 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain Smoothelin PF12510.8 PVD31202.1 - 4e-07 30.0 3.0 6.4e-07 29.3 3.0 1.3 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein Smoothelin PF12510.8 PVD31203.1 - 0.022 14.8 0.2 0.046 13.8 0.2 1.5 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein WD40 PF00400.32 PVD31204.1 - 3.6e-54 179.5 18.8 1.1e-08 35.5 0.3 9.2 8 0 0 8 8 8 7 WD domain, G-beta repeat HECT PF00632.25 PVD31204.1 - 1.7e-16 60.6 0.0 3.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC4_WD40 PF12894.7 PVD31204.1 - 1.4e-12 47.8 1.0 0.1 12.9 0.0 5.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD31204.1 - 9.6e-07 27.8 2.8 0.15 10.7 0.0 5.1 3 2 2 5 5 5 4 Nucleoporin Nup120/160 LisH PF08513.11 PVD31204.1 - 0.027 14.4 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 LisH INTS5_N PF14837.6 PVD31204.1 - 0.028 14.0 1.2 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Nucleoporin_N PF08801.11 PVD31204.1 - 0.061 12.1 0.0 2.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like Cpn60_TCP1 PF00118.24 PVD31205.1 - 1.4e-122 409.8 3.8 1.6e-105 353.6 4.2 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Terminase_2 PF03592.16 PVD31205.1 - 0.11 13.0 0.6 0.21 12.1 0.6 1.5 1 0 0 1 1 1 0 Terminase small subunit FAD_binding_3 PF01494.19 PVD31206.1 - 2.9e-09 36.6 0.0 4.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 PVD31206.1 - 3.3e-05 22.9 0.0 0.00066 18.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase SE PF08491.10 PVD31206.1 - 0.0032 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 PVD31206.1 - 0.0045 16.1 0.0 0.047 12.7 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 PVD31206.1 - 0.0054 16.4 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase IP_trans PF02121.18 PVD31207.1 - 1.4e-108 362.1 0.2 1.7e-108 361.9 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Arm PF00514.23 PVD31208.1 - 1.7e-11 43.7 0.4 0.073 13.1 0.0 6.8 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat BTB PF00651.31 PVD31208.1 - 4.7e-07 30.0 0.3 2.4e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain KAP PF05804.12 PVD31208.1 - 0.018 13.2 1.8 5.9 4.9 0.1 2.9 3 1 0 3 3 3 0 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 PVD31208.1 - 0.023 15.2 1.7 5.5 7.6 0.0 4.6 4 1 1 5 5 5 0 HEAT-like repeat PUL PF08324.11 PVD31208.1 - 0.042 13.1 0.5 0.14 11.4 0.1 2.1 2 0 0 2 2 2 0 PUL domain HEAT_2 PF13646.6 PVD31208.1 - 0.14 12.6 0.6 1.1 9.6 0.1 2.9 2 0 0 2 2 2 0 HEAT repeats PDZ PF00595.24 PVD31209.1 - 3.7e-11 43.2 0.0 1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD31209.1 - 2.9e-09 36.6 0.0 5.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD31209.1 - 0.0026 18.0 0.6 0.012 15.9 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PNISR PF15996.5 PVD31209.1 - 0.44 10.8 15.4 0.6 10.4 15.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR FAP PF07174.11 PVD31209.1 - 0.47 9.9 6.3 2.9 7.3 6.3 1.9 1 1 0 1 1 1 0 Fibronectin-attachment protein (FAP) PI3K_1B_p101 PF10486.9 PVD31209.1 - 2 6.1 7.7 2.3 5.9 7.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FCP1_C PF09309.10 PVD31209.1 - 4.9 6.9 18.7 8.4 6.2 18.7 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Presenilin PF01080.17 PVD31209.1 - 9.5 4.9 9.1 11 4.6 9.1 1.1 1 0 0 1 1 1 0 Presenilin Myosin_head PF00063.21 PVD31210.1 - 2.1e-115 386.5 0.0 1.2e-114 384.0 0.0 2.4 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 PVD31210.1 - 3.3e-18 65.0 166.6 8.7e-18 63.6 142.8 2.9 1 1 1 2 2 2 2 Myosin tail IQ PF00612.27 PVD31210.1 - 0.0039 16.9 0.0 0.012 15.3 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 PVD31210.1 - 0.23 11.8 0.0 0.23 11.8 0.0 5.5 3 2 0 3 3 3 0 AAA ATPase domain DUF4079 PF13301.6 PVD31211.1 - 7.3 6.7 11.5 2.6 8.2 8.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Trypsin PF00089.26 PVD31212.1 - 1.2e-64 218.2 2.7 2.6e-64 217.1 2.7 1.6 1 0 0 1 1 1 1 Trypsin MAM PF00629.23 PVD31212.1 - 8.8e-41 139.5 2.1 3.9e-20 72.4 0.3 2.6 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu CUB PF00431.20 PVD31212.1 - 1.2e-17 64.2 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 CUB domain DUF1986 PF09342.11 PVD31212.1 - 6.4e-10 39.4 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 PVD31212.1 - 5.6e-06 26.5 12.2 1.5e-05 25.1 12.2 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A UQ_con PF00179.26 PVD31213.1 - 1.5e-14 53.8 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FKBP_C PF00254.28 PVD31214.1 - 5e-14 52.4 0.0 1.7e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PVD31214.1 - 2.9e-12 45.8 1.6 3.8e-05 23.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31214.1 - 5.3e-07 29.3 1.8 0.0099 15.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31214.1 - 0.00013 21.9 2.3 0.18 12.1 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31214.1 - 0.00018 21.3 0.2 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31214.1 - 0.0022 18.5 0.1 1.1 9.9 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 PVD31214.1 - 0.0055 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 PVD31214.1 - 0.01 16.1 1.3 1.9 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 PVD31214.1 - 0.024 14.3 0.6 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 PVD31214.1 - 0.029 15.2 0.0 0.29 12.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UCH PF00443.29 PVD31214.1 - 0.085 12.3 0.4 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPR_16 PF13432.6 PVD31214.1 - 0.11 13.1 0.2 2.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD31214.1 - 0.13 12.5 1.1 4.6 7.5 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 PVD31214.1 - 0.28 11.3 5.6 0.069 13.2 1.3 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 PVD31214.1 - 0.32 11.0 1.7 0.73 9.9 1.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 PVD31215.1 - 9.1e-59 199.0 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31215.1 - 1.2e-27 96.9 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 PVD31215.1 - 0.15 11.7 1.2 2 8.0 0.3 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1232 PF06803.12 PVD31215.1 - 0.16 11.8 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Thioredoxin_8 PF13905.6 PVD31216.1 - 2.6e-32 111.0 0.0 1.8e-27 95.5 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin PF00085.20 PVD31216.1 - 7.4e-10 38.7 0.0 3.5e-06 26.9 0.0 3.3 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 PVD31216.1 - 2e-09 37.8 0.0 4.1e-05 24.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 PVD31216.1 - 1.7e-08 34.3 0.0 4.2e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 PVD31216.1 - 8.7e-08 32.1 0.0 4.4e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.6 PVD31216.1 - 5.4e-07 29.7 0.1 1.1e-05 25.4 0.0 2.8 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PVD31216.1 - 0.0037 17.4 0.0 0.036 14.2 0.0 2.6 3 1 0 3 3 3 1 Thioredoxin-like TraF PF13728.6 PVD31216.1 - 0.021 14.7 0.0 13 5.5 0.0 3.3 3 1 0 3 3 3 0 F plasmid transfer operon protein SCO1-SenC PF02630.14 PVD31216.1 - 0.024 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Thioredoxin_9 PF14595.6 PVD31216.1 - 0.075 12.8 0.0 1.2 8.9 0.0 2.8 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 PVD31216.1 - 0.12 12.1 0.0 7.4 6.2 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin Cu2_monoox_C PF03712.15 PVD31217.1 - 1.4e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD31218.1 - 0.0006 20.1 0.0 0.00064 20.0 0.0 1.1 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Endonuclease_1 PF04231.13 PVD31218.1 - 0.039 13.6 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Endonuclease I Prokineticin PF06607.11 PVD31219.1 - 2.7e-05 24.4 12.1 0.00081 19.7 4.7 2.2 2 0 0 2 2 2 2 Prokineticin MLTD_N PF06474.12 PVD31219.1 - 0.0011 19.1 1.2 2 8.7 0.1 2.6 2 0 0 2 2 2 2 MltD lipid attachment motif Dickkopf_N PF04706.12 PVD31219.1 - 0.0035 17.8 25.3 0.0075 16.7 6.4 2.7 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region RNase_PH_C PF03725.15 PVD31219.1 - 0.0062 16.5 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 CX PF01705.19 PVD31219.1 - 0.85 10.2 7.5 11 6.7 0.9 2.6 2 0 0 2 2 2 0 CX module Colipase-like PF15083.6 PVD31219.1 - 1.6 8.9 20.4 7.8 6.7 7.1 2.4 1 1 1 2 2 2 0 Colipase-like Ras PF00071.22 PVD31220.1 - 6.4e-39 133.2 0.0 7.8e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31220.1 - 6.2e-17 61.9 0.0 9.2e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31220.1 - 2.2e-05 24.0 0.0 3.7e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD31220.1 - 0.0019 17.8 0.0 0.0044 16.6 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PVD31220.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD31220.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Fib_alpha PF08702.10 PVD31222.1 - 4.6e-06 26.9 12.9 0.00031 20.9 3.6 2.7 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 PVD31222.1 - 1.8e-05 24.7 19.1 0.022 14.8 2.0 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PVD31222.1 - 2.1e-05 24.6 11.5 0.12 12.5 2.9 3.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus GPS2_interact PF15784.5 PVD31222.1 - 0.00075 19.9 31.9 11 6.5 1.0 9.0 1 1 4 5 5 5 0 G-protein pathway suppressor 2-interacting domain Sec3_C PF09763.9 PVD31222.1 - 0.002 16.6 0.1 0.67 8.3 0.0 2.9 3 0 0 3 3 3 1 Exocyst complex component Sec3 FlaC_arch PF05377.11 PVD31222.1 - 0.0044 17.4 0.5 17 5.9 0.1 4.1 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) CCDC53 PF10152.9 PVD31222.1 - 0.0065 16.9 0.1 5.7 7.3 0.1 3.2 2 1 1 3 3 3 1 Subunit CCDC53 of WASH complex FliD_C PF07195.12 PVD31222.1 - 0.0086 15.5 6.4 6.7 6.0 0.4 4.0 1 1 3 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF724 PF05266.14 PVD31222.1 - 0.0091 15.8 0.0 3 7.6 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF724) Tropomyosin PF00261.20 PVD31222.1 - 0.013 14.9 0.8 8.2 5.7 0.1 3.0 1 1 0 2 2 2 0 Tropomyosin HsbA PF12296.8 PVD31222.1 - 0.019 15.4 7.8 0.56 10.6 0.6 3.8 2 1 1 3 3 3 0 Hydrophobic surface binding protein A SlyX PF04102.12 PVD31222.1 - 0.042 14.5 4.7 7.7 7.2 0.1 3.7 2 1 0 3 3 3 0 SlyX Csm1_N PF18504.1 PVD31222.1 - 0.047 14.0 0.5 36 4.8 0.0 4.4 4 2 1 5 5 5 0 Csm1 N-terminal domain DUF3287 PF11690.8 PVD31222.1 - 0.055 13.2 28.6 2.4 7.9 5.8 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF3287) Uds1 PF15456.6 PVD31222.1 - 0.12 12.6 7.7 8.4 6.6 3.4 3.9 1 1 2 3 3 3 0 Up-regulated During Septation Tropomyosin_1 PF12718.7 PVD31222.1 - 0.14 12.3 0.0 15 5.7 0.0 2.5 1 1 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 PVD31222.1 - 0.15 12.6 13.7 24 5.5 3.5 4.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein MPS2 PF17060.5 PVD31222.1 - 0.16 11.2 5.0 2.9 7.1 1.5 2.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 FAM76 PF16046.5 PVD31222.1 - 0.16 11.3 10.6 2.4 7.4 0.6 3.7 2 1 2 4 4 4 0 FAM76 protein DUF16 PF01519.16 PVD31222.1 - 0.27 11.7 5.5 21 5.7 2.3 3.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 E2R135 PF11570.8 PVD31222.1 - 0.35 11.2 2.9 51 4.1 0.1 4.0 1 1 2 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 MitMem_reg PF13012.6 PVD31222.1 - 0.8 10.1 3.5 83 3.6 3.5 3.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Prefoldin_3 PF13758.6 PVD31222.1 - 1.9 8.6 29.8 7.4 6.7 1.0 5.5 3 3 1 4 4 4 0 Prefoldin subunit DUF4164 PF13747.6 PVD31222.1 - 4.4 7.6 17.6 6.1 7.2 2.5 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) IFT57 PF10498.9 PVD31222.1 - 4.5 6.1 6.7 3.4 6.6 1.6 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 XhlA PF10779.9 PVD31222.1 - 4.6 7.5 17.6 8.6 6.7 0.5 4.7 3 3 1 4 4 4 0 Haemolysin XhlA HCMV_UL139 PF12507.8 PVD31222.1 - 5.4 7.4 11.8 11 6.5 0.2 4.0 1 1 3 4 4 4 0 Human Cytomegalovirus UL139 protein MTABC_N PF16185.5 PVD31224.1 - 1.9e-41 142.2 6.5 1.9e-41 142.2 6.5 2.9 3 1 0 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 PVD31224.1 - 6.2e-34 117.9 12.2 6.2e-34 117.9 12.2 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD31224.1 - 1.5e-20 74.1 0.0 2.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PVD31224.1 - 0.0063 16.2 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD31224.1 - 0.0081 16.6 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 PVD31224.1 - 0.015 14.9 0.0 0.036 13.6 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD31224.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PVD31224.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PVD31224.1 - 0.051 14.1 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PVD31224.1 - 0.17 11.9 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ATG16 PF08614.11 PVD31225.1 - 0.00013 22.3 39.4 0.0067 16.7 17.4 2.8 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 PVD31225.1 - 0.1 12.6 46.3 0.03 14.3 10.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 PVD31225.1 - 0.12 12.1 29.9 0.12 12.0 7.3 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 FAM76 PF16046.5 PVD31225.1 - 0.28 10.5 36.0 0.23 10.8 11.3 3.2 1 1 2 3 3 3 0 FAM76 protein RNA_pol_Rpb2_2 PF04561.14 PVD31225.1 - 0.35 10.5 12.1 0.33 10.5 3.9 2.3 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 2 DUF3584 PF12128.8 PVD31225.1 - 0.38 8.2 38.5 0.05 11.1 28.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 PVD31225.1 - 1.9 7.7 29.9 61 2.8 29.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 PVD31225.1 - 3.2 8.0 34.1 0.044 14.0 5.7 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.6 PVD31225.1 - 3.5 7.8 32.0 1 9.5 19.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fez1 PF06818.15 PVD31225.1 - 5.9 7.3 36.3 2.5 8.5 14.7 2.6 1 1 2 3 3 3 0 Fez1 DUF1192 PF06698.11 PVD31225.1 - 7.7 6.7 13.2 0.12 12.4 0.9 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) UPF0242 PF06785.11 PVD31225.1 - 7.8 6.6 37.4 6 6.9 13.5 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 PVD31225.1 - 9.4 5.6 37.6 2.1 7.7 28.7 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATP_bind_1 PF03029.17 PVD31226.1 - 1.7e-86 290.0 0.1 1.9e-86 289.8 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PVD31226.1 - 0.0015 19.1 0.0 0.0039 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PVD31226.1 - 0.0024 18.2 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.18 PVD31226.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 PVD31226.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 PVD31226.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 PVD31226.1 - 0.016 15.6 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PVD31226.1 - 0.03 14.2 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 PVD31226.1 - 0.03 14.7 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD31226.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD31226.1 - 0.072 13.4 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD31226.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 PVD31226.1 - 0.097 12.6 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD31226.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 PVD31226.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 PVD31226.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ADK PF00406.22 PVD31226.1 - 0.15 12.2 0.1 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase P21-Arc PF04062.14 PVD31227.1 - 2.1e-69 233.0 0.0 2.4e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DDE_Tnp_1 PF01609.21 PVD31227.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Tox-URI2 PF15653.6 PVD31227.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 URI fold toxin 2 Myb_DNA-bind_4 PF13837.6 PVD31228.1 - 4.3e-12 46.2 1.2 1.2e-11 44.8 1.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD31228.1 - 0.00035 20.8 0.3 0.00035 20.8 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 PVD31228.1 - 0.0028 17.9 0.4 0.0075 16.5 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD31228.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain POX PF07526.11 PVD31228.1 - 0.081 13.5 0.3 5.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Associated with HOX YebO PF13974.6 PVD31228.1 - 2.8 8.1 5.9 8.8 6.5 5.9 1.8 1 0 0 1 1 1 0 YebO-like protein DDE_Tnp_4 PF13359.6 PVD31229.1 - 3.5e-16 59.3 0.0 6.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 PVD31230.1 - 9.7e-15 54.2 0.1 1.5e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M-inducer_phosp PF06617.13 PVD31230.1 - 0.19 11.0 1.1 0.24 10.6 1.1 1.1 1 0 0 1 1 1 0 M-phase inducer phosphatase CPSase_L_D2 PF02786.17 PVD31231.1 - 1.5e-76 256.6 0.2 2.8e-76 255.7 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PVD31231.1 - 2.1e-47 160.2 1.0 6.3e-47 158.7 0.3 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PVD31231.1 - 4.9e-36 123.1 0.0 1.2e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PVD31231.1 - 4.3e-16 58.5 1.1 2.2e-15 56.2 0.9 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PVD31231.1 - 4e-11 42.8 0.1 1e-10 41.5 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PVD31231.1 - 5.9e-09 35.7 0.4 2.5e-08 33.7 0.3 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 PVD31231.1 - 1.3e-06 28.5 1.0 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 PVD31231.1 - 2.3e-06 27.3 4.4 0.027 14.3 0.1 3.1 4 0 0 4 4 4 2 Biotin-lipoyl like HlyD_3 PF13437.6 PVD31231.1 - 5.1e-05 23.9 1.0 0.17 12.6 0.0 3.5 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.11 PVD31231.1 - 0.0012 18.4 0.5 0.027 14.0 0.0 2.7 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 PVD31231.1 - 0.0064 15.8 0.2 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 PVD31231.1 - 0.013 14.7 0.8 1.8 7.7 0.0 2.7 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ntox43 PF15537.6 PVD31231.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 43 GARS_A PF01071.19 PVD31231.1 - 0.12 12.1 0.3 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 PVD31231.1 - 0.19 11.7 1.0 1.4 8.9 0.3 2.8 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain F-box-like PF12937.7 PVD31232.1 - 7.2e-12 45.0 4.2 1.7e-11 43.8 4.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 PVD31232.1 - 6.6e-11 42.6 6.1 0.00037 21.2 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box PF00646.33 PVD31232.1 - 4.1e-08 32.9 2.9 1.2e-07 31.5 2.9 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD31232.1 - 0.0067 16.3 0.8 0.024 14.5 0.8 1.9 1 0 0 1 1 1 1 F-box BBS2_Mid PF14783.6 PVD31232.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region NAD_binding_8 PF13450.6 PVD31233.1 - 4e-17 62.2 0.2 1.3e-16 60.6 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PVD31233.1 - 7.9e-15 55.1 0.0 6.2e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 PVD31233.1 - 8.2e-14 51.5 0.0 5.2e-10 39.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 PVD31233.1 - 4.7e-07 29.5 0.3 8.3e-07 28.7 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 PVD31233.1 - 1.8e-06 27.8 3.4 0.00051 19.7 3.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 PVD31233.1 - 1.6e-05 24.3 0.0 7.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PVD31233.1 - 1.7e-05 24.2 1.3 2.7e-05 23.6 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD31233.1 - 6.6e-05 22.3 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD31233.1 - 9.4e-05 21.3 2.0 0.00018 20.4 2.0 1.4 1 0 0 1 1 1 1 HI0933-like protein GMC_oxred_N PF00732.19 PVD31233.1 - 0.00071 19.0 0.4 0.0031 16.9 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 PVD31233.1 - 0.003 16.9 0.4 0.0049 16.2 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD31233.1 - 0.003 18.1 0.4 0.0089 16.6 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 PVD31233.1 - 0.0036 16.2 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 MCRA family GDI PF00996.18 PVD31233.1 - 0.0043 15.6 0.2 0.23 9.9 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor GIDA PF01134.22 PVD31233.1 - 0.018 14.2 2.4 0.027 13.5 2.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PHD_4 PF16866.5 PVD31234.1 - 8.2e-19 67.5 9.5 8.2e-19 67.5 9.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-CXXC PF02008.20 PVD31234.1 - 1.4e-13 50.7 23.3 1.4e-13 50.7 23.3 2.4 2 0 0 2 2 2 1 CXXC zinc finger domain F-box-like PF12937.7 PVD31234.1 - 1.3e-06 28.2 3.7 3.2e-06 26.9 3.7 1.6 1 0 0 1 1 1 1 F-box-like JHD PF17811.1 PVD31234.1 - 1.6e-06 28.6 2.3 8.9e-06 26.2 0.1 2.9 3 0 0 3 3 3 1 Jumonji helical domain LRR_4 PF12799.7 PVD31234.1 - 0.0001 22.6 1.8 0.52 10.8 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 PVD31234.1 - 0.00015 21.5 0.5 0.00015 21.5 0.5 2.6 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 PVD31234.1 - 0.029 14.4 6.3 2.4 8.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 PVD31234.1 - 0.76 9.6 6.1 15 5.5 0.8 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 PVD31234.1 - 7.6 7.5 9.1 1.1e+02 4.0 0.1 5.2 3 2 0 3 3 3 0 Leucine Rich Repeat Orai-1 PF07856.12 PVD31235.1 - 1.3e-45 155.2 3.7 1.5e-45 155.0 3.7 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF5367 PF17329.2 PVD31235.1 - 0.051 13.7 2.1 0.13 12.4 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF4492 PF14899.6 PVD31235.1 - 0.064 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) SLATT_5 PF18160.1 PVD31235.1 - 0.14 11.5 0.4 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF202 PF02656.15 PVD31235.1 - 0.59 10.6 5.2 0.67 10.4 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3624 PF12292.8 PVD31235.1 - 2.1 8.8 6.7 3.7 8.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) 7tm_1 PF00001.21 PVD31235.1 - 2.2 7.5 9.2 0.48 9.7 4.4 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Syndecan PF01034.20 PVD31235.1 - 3.9 7.5 4.7 55 3.8 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain DUF2207 PF09972.9 PVD31235.1 - 4.7 5.9 5.8 5.3 5.7 5.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MORN PF02493.20 PVD31236.1 - 1.3e-32 109.7 45.0 4.7e-07 29.3 0.8 7.0 7 0 0 7 7 7 6 MORN repeat DUF4028 PF13220.6 PVD31236.1 - 0.22 11.3 4.3 0.2 11.5 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4028) Kazal_2 PF07648.15 PVD31237.1 - 2.7e-08 33.8 10.1 4.6e-05 23.4 4.6 2.7 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD31237.1 - 2.6e-06 27.3 10.6 4.1e-05 23.5 5.4 2.5 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Sulfotransfer_1 PF00685.27 PVD31238.1 - 1.6e-20 73.7 0.2 1.3e-19 70.7 0.1 1.8 1 1 1 2 2 2 2 Sulfotransferase domain NIF3 PF01784.18 PVD31239.1 - 5.1e-57 193.3 0.0 6.9e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) MFS_1 PF07690.16 PVD31240.1 - 7.1e-38 130.4 24.7 7.1e-38 130.4 24.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 PVD31240.1 - 1.1e-15 57.0 15.3 6.2e-06 24.8 0.7 4.1 3 1 1 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 PVD31240.1 - 1.4e-14 53.9 14.2 2.1e-14 53.3 7.7 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD31240.1 - 1.5e-08 33.6 22.9 2.8e-06 26.1 5.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein OppC_N PF12911.7 PVD31240.1 - 0.72 9.9 3.2 2.9 7.9 0.0 3.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Tetraspanin PF00335.20 PVD31240.1 - 6.7 6.4 8.1 16 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetraspanin family RasGAP PF00616.19 PVD31241.1 - 3.3e-29 102.1 1.8 3e-23 82.6 0.2 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 PVD31241.1 - 6.1e-23 81.5 0.1 2.3e-22 79.7 0.1 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 PVD31241.1 - 0.0019 18.2 0.3 0.0019 18.2 0.3 3.8 4 1 0 4 4 4 1 Cell morphogenesis C-terminal HTH_37 PF13744.6 PVD31241.1 - 0.069 13.1 0.7 0.83 9.6 0.2 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain CRAL_TRIO PF00650.20 PVD31241.1 - 3.1 7.5 9.1 0.31 10.8 0.4 3.7 4 0 0 4 4 4 0 CRAL/TRIO domain Anp1 PF03452.14 PVD31242.1 - 1.1e-52 179.0 0.0 1.5e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 PVD31242.1 - 8.4e-08 32.2 0.0 2.2e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 CAP59_mtransfer PF11735.8 PVD31242.1 - 0.0005 19.8 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_3 PF13641.6 PVD31242.1 - 0.00076 19.4 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PVD31242.1 - 0.0025 18.3 0.0 0.0051 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 NTP_transf_3 PF12804.7 PVD31242.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain ATP_bind_2 PF03668.15 PVD31242.1 - 0.082 12.2 0.0 0.75 9.0 0.0 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family RGS PF00615.19 PVD31243.1 - 2.6e-30 105.1 8.7 3.7e-12 46.5 0.4 3.3 3 0 0 3 3 3 3 Regulator of G protein signaling domain Glyco_hydro_1 PF00232.18 PVD31244.1 - 0 1096.3 9.8 8.1e-171 568.4 2.9 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Cellulase PF00150.18 PVD31244.1 - 1.7e-06 27.7 2.1 0.0014 18.1 0.1 3.2 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 PVD31244.1 - 2.5e-05 24.7 0.4 2.2 8.6 0.0 4.4 4 0 0 4 4 4 2 GDSL-like Lipase/Acylhydrolase family DUF3258 PF11646.8 PVD31244.1 - 0.0022 18.1 0.1 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function DUF3258 DUF604 PF04646.12 PVD31244.1 - 0.082 12.3 0.0 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF604 DUF1168 PF06658.12 PVD31245.1 - 5.6e-41 139.5 24.0 1.1e-40 138.6 24.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4775 PF16001.5 PVD31245.1 - 0.11 11.9 22.1 0.13 11.7 22.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Pox_Ag35 PF03286.14 PVD31245.1 - 0.2 11.4 18.3 0.36 10.6 18.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.16 PVD31245.1 - 8.6 6.3 13.2 52 3.8 13.2 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 PVD31245.1 - 9.9 6.1 15.8 14 5.7 15.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CBM_14 PF01607.24 PVD31246.1 - 2e-22 79.1 19.0 2.7e-14 53.0 4.8 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.27 PVD31247.1 - 4e-20 72.4 0.0 4.2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31247.1 - 0.041 14.2 0.1 0.079 13.3 0.0 1.5 1 1 1 2 2 2 0 Sulfotransferase family Innexin PF00876.18 PVD31251.1 - 1.4e-80 271.3 21.8 1.6e-80 271.1 21.8 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 PVD31252.1 - 1.6e-79 267.8 23.8 1.8e-79 267.6 23.8 1.0 1 0 0 1 1 1 1 Innexin DUF1911 PF08929.10 PVD31252.1 - 0.027 15.3 0.1 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Abhydrolase_1 PF00561.20 PVD31253.1 - 3.8e-06 26.7 0.0 0.00018 21.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD31253.1 - 0.00023 20.5 0.0 0.00042 19.7 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PVD31253.1 - 0.015 14.9 0.0 0.25 10.9 0.0 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Guanylate_cyc_2 PF09778.9 PVD31255.1 - 8e-72 241.0 2.0 9.1e-72 240.8 2.0 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 PVD31255.1 - 1.9e-07 31.7 0.0 2.6e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 PVD31255.1 - 5.1e-05 23.1 0.0 0.00043 20.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase C39 family DUF3335 PF11814.8 PVD31255.1 - 0.00056 19.4 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 PVD31255.1 - 0.0027 17.7 0.1 2.2 8.3 0.0 2.3 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 RuBisCO_small PF00101.20 PVD31255.1 - 0.091 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain CRAL_TRIO PF00650.20 PVD31256.1 - 2.1e-26 92.5 0.1 6e-23 81.3 0.1 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain GOLD_2 PF13897.6 PVD31256.1 - 8.1e-06 26.4 0.7 0.0044 17.5 0.1 2.9 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 PVD31256.1 - 0.003 17.7 2.1 0.003 17.7 2.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain EMP24_GP25L PF01105.24 PVD31256.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PriA_3primeBD PF17764.1 PVD31256.1 - 0.071 13.0 0.9 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 3′ DNA-binding domain (3′BD) Chromo_shadow PF01393.19 PVD31256.1 - 0.081 13.0 1.6 5.3 7.2 0.3 2.5 2 0 0 2 2 2 0 Chromo shadow domain IL17 PF06083.11 PVD31257.1 - 2.1e-11 44.1 2.1 4.2e-11 43.2 2.1 1.5 1 0 0 1 1 1 1 Interleukin-17 DUF3678 PF12435.8 PVD31257.1 - 0.5 9.8 3.6 21 4.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3678) Glyoxalase PF00903.25 PVD31258.1 - 8.1e-18 64.9 0.8 2.2e-14 53.8 0.1 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PVD31258.1 - 3.9e-11 43.2 0.3 2.3e-05 24.6 0.3 3.1 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 PVD31258.1 - 1.7e-05 25.0 0.1 5.3e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 PVD31258.1 - 0.00064 19.9 1.0 1.1 9.3 0.0 2.8 2 1 1 3 3 3 2 Glyoxalase-like domain HTH_Mga PF08280.11 PVD31258.1 - 0.007 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Glyoxalase_6 PF18029.1 PVD31258.1 - 0.073 13.9 0.3 0.17 12.7 0.1 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain zf-CCCH_4 PF18044.1 PVD31259.1 - 2.6e-05 23.9 6.3 6.2e-05 22.7 6.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 PVD31259.1 - 0.00018 22.2 2.9 0.00028 21.6 0.1 2.5 3 0 0 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 PVD31259.1 - 0.015 15.3 9.8 0.04 14.0 9.8 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 PVD31259.1 - 0.018 15.0 4.2 0.04 13.8 4.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GTP_EFTU PF00009.27 PVD31260.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2207 PF09972.9 PVD31260.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MMR_HSR1 PF01926.23 PVD31260.1 - 0.021 14.9 0.0 0.11 12.5 0.0 1.9 1 1 0 2 2 2 0 50S ribosome-binding GTPase RED_C PF07807.11 PVD31260.1 - 0.034 14.6 0.5 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 RED-like protein C-terminal region NAD_synthase PF02540.17 PVD31260.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD synthase RNase_J_C PF17770.1 PVD31260.1 - 0.095 13.8 1.6 0.27 12.3 0.3 2.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain BLOC1_2 PF10046.9 PVD31260.1 - 3.1 8.2 7.0 2.4 8.5 0.7 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SNF PF00209.18 PVD31261.1 - 1e-196 654.7 32.5 1.2e-196 654.5 32.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3624 PF12292.8 PVD31261.1 - 3.5 8.1 7.7 0.71 10.3 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) DUF202 PF02656.15 PVD31261.1 - 6.2 7.3 9.4 14 6.3 2.0 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Cir_N PF10197.9 PVD31265.1 - 8.6e-08 32.2 9.8 8.6e-08 32.2 9.8 5.4 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR SR-25 PF10500.9 PVD31265.1 - 2.7 7.6 32.6 0.82 9.2 18.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3105 PF11303.8 PVD31266.1 - 1.3e-33 115.9 0.3 2.7e-33 114.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3105) PS_Dcarbxylase PF02666.15 PVD31267.1 - 5.3e-63 212.2 0.0 6.2e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 PVD31267.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit DUF3556 PF12077.8 PVD31268.1 - 0.047 12.1 0.1 0.054 11.9 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Med31 PF05669.12 PVD31270.1 - 1.6e-38 130.6 8.6 2.3e-38 130.1 8.6 1.2 1 0 0 1 1 1 1 SOH1 Phage-A118_gp45 PF10653.9 PVD31270.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 INTS2 PF14750.6 PVD31271.1 - 0 1344.2 23.3 0 1344.0 23.3 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 HAUS-augmin3 PF14932.6 PVD31271.1 - 0.036 13.6 1.7 0.059 12.9 0.2 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2999 PF11212.8 PVD31271.1 - 0.16 12.3 0.7 1.5 9.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Trypsin PF00089.26 PVD31272.1 - 2.1e-41 142.2 0.0 4.6e-28 98.5 0.0 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 PVD31272.1 - 4.8e-07 30.8 0.0 1.1e-06 29.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Carb_anhydrase PF00194.21 PVD31273.1 - 4.3e-84 282.0 0.0 7.7e-84 281.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Es2 PF09751.9 PVD31274.1 - 9.2e-78 262.9 6.4 9.2e-78 262.9 6.4 2.2 2 0 0 2 2 2 2 Nuclear protein Es2 DUF647 PF04884.14 PVD31275.1 - 4.2e-97 324.5 3.4 5.8e-97 324.1 3.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis tRNA_anti-codon PF01336.25 PVD31275.1 - 0.039 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Pkinase_Tyr PF07714.17 PVD31276.1 - 2.6e-53 181.0 0.0 5.4e-53 179.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD31276.1 - 8.6e-43 146.6 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 PVD31276.1 - 4.7e-33 114.1 6.0 9e-33 113.2 6.0 1.5 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 PVD31276.1 - 0.00093 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.22 PVD31276.1 - 0.0042 16.9 8.6 0.0047 16.8 7.4 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 PVD31276.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family zf-RING-like PF08746.11 PVD31276.1 - 0.017 15.5 5.7 0.042 14.2 5.7 1.7 1 0 0 1 1 1 0 RING-like domain Kdo PF06293.14 PVD31276.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 PVD31276.1 - 1.5 9.2 4.7 3.3 8.1 4.7 1.6 1 0 0 1 1 1 0 Ring finger domain Usp PF00582.26 PVD31277.1 - 7.8e-26 91.3 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family HutP PF09021.11 PVD31277.1 - 0.02 15.2 0.2 0.027 14.8 0.2 1.2 1 0 0 1 1 1 0 HutP WD40 PF00400.32 PVD31278.1 - 3.1e-12 46.8 6.2 0.0017 19.1 0.0 6.4 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD31278.1 - 1e-08 35.3 0.0 8.4e-05 22.8 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD31278.1 - 0.00022 20.3 0.0 0.013 14.5 0.0 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD31278.1 - 0.013 15.4 0.1 0.081 12.8 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF551 PF04448.12 PVD31280.1 - 0.011 16.7 20.6 11 7.0 0.4 6.6 5 0 0 5 5 5 0 Protein of unknown function (DUF551) Melibiase_2 PF16499.5 PVD31280.1 - 0.06 12.5 0.2 7.1 5.7 0.0 3.1 3 0 0 3 3 3 0 Alpha galactosidase A RPN5_C PF18098.1 PVD31280.1 - 0.24 11.5 0.7 20 5.4 0.2 2.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Ion_trans_2 PF07885.16 PVD31282.1 - 2.4e-31 107.5 8.0 6.3e-16 58.1 1.9 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 PVD31282.1 - 0.0035 16.6 0.1 0.24 10.6 0.0 2.6 3 0 0 3 3 3 2 Ion transport protein SMBP PF16785.5 PVD31283.1 - 1.7 8.9 66.9 0.27 11.5 4.0 7.2 2 1 6 8 8 8 0 Small metal-binding protein 7tm_1 PF00001.21 PVD31284.1 - 2.9e-06 26.8 21.2 4.8e-06 26.1 21.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD31284.1 - 3.6e-06 26.5 18.8 0.00025 20.4 10.1 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Sru PF10322.9 PVD31284.1 - 0.029 13.7 15.0 0.039 13.3 14.4 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru MHC_I_3 PF16497.5 PVD31284.1 - 0.095 12.2 1.3 0.15 11.5 1.3 1.3 1 0 0 1 1 1 0 MHC-I family domain EST1_DNA_bind PF10373.9 PVD31284.1 - 0.098 12.1 1.0 0.17 11.3 1.0 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF3169 PF11368.8 PVD31284.1 - 2.2 7.7 9.9 0.17 11.4 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4680 PF15730.5 PVD31285.1 - 3.6 7.9 8.3 1.4 9.2 5.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4680) 7TM_GPCR_Srw PF10324.9 PVD31287.1 - 8.2e-08 31.9 8.4 3.2e-06 26.6 0.6 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD31287.1 - 9e-07 28.5 19.3 1.7e-06 27.6 19.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DIM PF08194.12 PVD31288.1 - 0.1 12.8 0.8 0.1 12.8 0.8 3.1 2 1 0 2 2 2 0 DIM protein Tmemb_9 PF05434.11 PVD31288.1 - 0.98 9.3 11.5 0.062 13.2 6.5 1.6 1 1 1 2 2 2 0 TMEM9 ODV-E18 PF10717.9 PVD31288.1 - 1.6 8.7 10.0 0.063 13.2 1.8 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 7tm_1 PF00001.21 PVD31290.1 - 7.7e-10 38.5 19.6 1.1e-09 38.1 19.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD31290.1 - 3.9e-09 36.2 16.9 9.7e-08 31.6 7.8 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD31291.1 - 1.3e-08 34.5 19.5 2.1e-08 33.8 19.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD31291.1 - 4.4e-08 32.8 17.2 6.5e-07 28.9 6.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw PhrC_PhrF PF11131.8 PVD31291.1 - 0.33 10.6 2.0 0.81 9.3 2.0 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling Plasmodium_Vir PF05795.11 PVD31293.1 - 0.53 9.7 1.1 0.64 9.4 1.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 PVD31293.1 - 1 8.3 4.2 1.4 7.8 4.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 PVD31293.1 - 2.9 6.1 8.0 3.3 5.9 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sulfotransfer_1 PF00685.27 PVD31295.1 - 4.1e-28 98.6 0.0 4.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31295.1 - 0.00013 22.4 0.0 0.00019 21.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD31296.1 - 2.1e-32 112.7 0.1 1.2e-28 100.3 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31296.1 - 1.3e-05 25.7 0.0 5e-05 23.8 0.0 1.8 1 1 1 2 2 2 1 Sulfotransferase family CCAP PF11105.8 PVD31297.1 - 0.14 12.1 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Sulfotransfer_1 PF00685.27 PVD31299.1 - 9.9e-40 136.7 0.3 1.2e-38 133.1 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain DNA_pol_delta_4 PF04081.13 PVD31299.1 - 2e-18 67.0 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Sulfotransfer_3 PF13469.6 PVD31299.1 - 1.6e-07 31.9 0.0 1.8e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family FMO-like PF00743.19 PVD31303.1 - 6.4e-169 562.8 0.0 2.3e-118 395.9 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PVD31303.1 - 7.7e-19 68.1 0.1 1.1e-11 44.5 0.0 3.7 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD31303.1 - 1.9e-10 40.4 0.3 4.7e-06 26.0 0.0 4.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 PVD31303.1 - 6e-08 32.3 0.0 0.00039 19.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD31303.1 - 0.0043 17.6 1.1 0.093 13.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 PVD31303.1 - 0.03 14.4 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 PVD31303.1 - 0.052 13.5 0.3 9 6.3 0.0 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 PVD31303.1 - 0.06 12.6 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 PVD31303.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 PVD31303.1 - 0.085 13.3 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding POB3_N PF17292.2 PVD31304.1 - 5e-30 103.8 0.1 1.4e-24 86.3 0.1 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 PVD31304.1 - 1.1e-24 86.1 0.2 4.9e-24 84.0 0.2 2.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 PVD31304.1 - 3.8e-23 81.7 0.0 1.1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like HMG_box PF00505.19 PVD31304.1 - 9.2e-23 80.5 5.1 9.2e-23 80.5 5.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD31304.1 - 4.3e-12 46.5 4.5 4.3e-12 46.5 4.5 2.5 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 PVD31304.1 - 0.013 16.0 7.3 0.021 15.4 6.2 1.9 1 1 0 1 1 1 0 YABBY protein KTSC PF13619.6 PVD31304.1 - 0.037 13.8 0.1 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 KTSC domain Asparaginase_2 PF01112.18 PVD31305.1 - 0.062 12.3 0.1 7 5.6 0.0 2.3 2 0 0 2 2 2 0 Asparaginase Lipocalin PF00061.23 PVD31306.1 - 7.7e-10 39.1 1.3 8e-10 39.1 1.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 PVD31306.1 - 0.014 15.3 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family DUF5565 PF17720.1 PVD31306.1 - 0.093 11.6 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Peptidase_M10 PF00413.24 PVD31307.1 - 1.6e-50 171.0 0.2 7.3e-50 168.9 0.1 1.9 2 0 0 2 2 2 1 Matrixin PG_binding_1 PF01471.18 PVD31307.1 - 2.3e-09 37.3 0.1 6.5e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 PVD31307.1 - 3.2e-07 30.2 10.3 4.4e-05 23.3 0.5 4.3 4 0 0 4 4 4 2 Hemopexin Astacin PF01400.24 PVD31307.1 - 0.00016 21.4 0.2 0.075 12.6 0.2 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 PVD31307.1 - 0.0037 16.3 0.4 0.0066 15.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 PVD31307.1 - 0.018 15.6 0.2 0.043 14.3 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 PVD31307.1 - 0.036 13.3 0.6 0.062 12.5 0.6 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 PVD31307.1 - 0.039 13.6 1.2 0.071 12.7 1.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SSP160 PF06933.11 PVD31307.1 - 0.051 11.8 7.2 0.073 11.3 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Reprolysin_5 PF13688.6 PVD31307.1 - 0.065 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 PVD31307.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M57 PF12388.8 PVD31307.1 - 0.5 9.9 2.7 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Mucin PF01456.17 PVD31307.1 - 9.9 6.2 14.9 18 5.3 14.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 PVD31308.1 - 4.1e-76 255.8 0.0 6.4e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31308.1 - 2.2e-41 141.8 0.0 4.3e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 PVD31308.1 - 1.2e-11 43.8 18.5 0.0043 17.2 0.0 6.8 7 0 0 7 7 5 4 HEAT repeat HEAT_2 PF13646.6 PVD31308.1 - 1.3e-11 44.8 0.1 0.00013 22.3 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 PVD31308.1 - 2.2e-10 40.8 7.4 0.0039 17.7 0.0 5.6 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.23 PVD31308.1 - 2.5e-07 30.5 12.2 7.5e-05 22.6 0.1 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 PVD31308.1 - 1e-06 28.9 4.1 0.0022 18.1 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 PVD31308.1 - 6.3e-05 22.4 0.0 0.00039 19.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD31308.1 - 0.0025 16.7 0.0 0.0045 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Atx10homo_assoc PF09759.9 PVD31308.1 - 0.0027 17.7 0.5 0.048 13.7 0.1 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 PVD31308.1 - 0.056 14.0 0.0 0.32 11.6 0.0 2.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Haspin_kinase PF12330.8 PVD31308.1 - 0.062 12.2 0.0 0.16 10.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PVD31308.1 - 0.15 12.0 0.0 0.5 10.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family U3snoRNP10 PF12397.8 PVD31308.1 - 0.19 12.1 3.1 1.2 9.5 0.9 3.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 RasGEF_N_2 PF14663.6 PVD31308.1 - 3.1 8.2 6.0 7.5 7.0 0.7 3.6 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_L18p PF00861.22 PVD31310.1 - 2.1e-07 31.3 0.0 2.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast STN1_2 PF09170.10 PVD31311.1 - 4.4e-11 43.3 0.2 6.7e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 PVD31311.1 - 1.9e-06 27.7 0.0 4.8e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 PVD31311.1 - 4.2e-05 22.6 0.0 0.00011 21.3 0.0 1.7 1 1 0 1 1 1 1 Telomere regulation protein Stn1 GntR PF00392.21 PVD31311.1 - 0.067 12.8 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Peptidase_M10 PF00413.24 PVD31312.1 - 2.2e-56 190.1 0.0 3.1e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 PVD31312.1 - 1.1e-14 54.0 2.7 4.8e-10 39.2 0.7 3.6 3 0 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.18 PVD31312.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 PVD31312.1 - 0.00066 19.3 0.3 0.84 9.2 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 PVD31312.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 PVD31312.1 - 0.017 14.1 0.2 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 PVD31312.1 - 0.027 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 PVD31312.1 - 0.05 14.1 1.5 0.074 13.6 0.2 2.0 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF716 PF04819.12 PVD31313.1 - 3.6e-05 23.4 2.7 3.6e-05 23.4 2.7 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF716) DUF716 PF04819.12 PVD31314.1 - 5.2e-13 48.8 4.6 9.3e-13 48.0 4.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) Pyr_redox_2 PF07992.14 PVD31315.1 - 9.7e-57 192.4 0.3 1.4e-56 191.9 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 PVD31315.1 - 6.1e-20 71.0 0.3 1.3e-19 69.9 0.3 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 PVD31315.1 - 8.7e-11 42.2 0.8 9.5e-07 29.3 0.1 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD31315.1 - 2.4e-10 40.2 0.6 2.6e-09 36.8 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 PVD31315.1 - 2.8e-10 40.1 0.0 1.2e-09 38.0 0.0 2.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 PVD31315.1 - 1.3e-08 35.2 0.0 5.8e-08 33.2 0.0 2.2 2 0 0 2 2 1 1 Reductase C-terminal PIG-L PF02585.17 PVD31315.1 - 1.1e-06 29.3 0.0 2.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HI0933_like PF03486.14 PVD31315.1 - 0.00064 18.5 0.0 0.53 8.9 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein DUF2704 PF10866.8 PVD31315.1 - 0.012 15.5 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2704) NAD_binding_8 PF13450.6 PVD31315.1 - 0.029 14.6 0.1 0.077 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PVD31315.1 - 0.078 12.0 1.0 2.1 7.4 0.2 3.2 2 1 1 3 3 3 0 FAD binding domain DEAD PF00270.29 PVD31316.1 - 1.6e-44 151.8 0.0 2.9e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD31316.1 - 6e-24 84.5 0.0 2.6e-22 79.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PVD31316.1 - 8.7e-22 77.1 0.0 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PVD31316.1 - 4e-05 23.7 0.8 8.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PVD31316.1 - 0.016 15.5 0.1 0.093 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyoxalase_3 PF13468.6 PVD31316.1 - 0.021 15.0 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Helicase_C_2 PF13307.6 PVD31316.1 - 0.44 10.7 0.0 0.44 10.7 0.0 2.6 3 1 1 4 4 4 0 Helicase C-terminal domain Baculo_helicase PF04735.12 PVD31317.1 - 0.9 7.0 3.3 0.81 7.1 0.2 1.9 2 0 0 2 2 2 0 Baculovirus DNA helicase 14-3-3 PF00244.20 PVD31318.1 - 5.4e-107 356.3 3.1 6.3e-107 356.1 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF722 PF05263.11 PVD31318.1 - 0.038 14.2 1.7 0.072 13.3 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Spb1_C PF07780.12 PVD31319.1 - 4.9e-54 183.2 26.3 6.8e-54 182.7 26.3 1.1 1 0 0 1 1 1 1 Spb1 C-terminal domain FtsJ PF01728.19 PVD31320.1 - 2.9e-54 183.8 0.1 6.6e-54 182.7 0.1 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 PVD31320.1 - 1.7e-43 148.3 19.8 1.7e-43 148.3 19.8 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3381) eIF-3c_N PF05470.12 PVD31321.1 - 1.4e-226 753.4 23.1 2.9e-226 752.4 23.1 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 PVD31321.1 - 3e-12 47.0 2.0 1.1e-11 45.2 0.1 2.9 3 0 0 3 3 3 1 PCI domain SR-25 PF10500.9 PVD31321.1 - 4 7.0 16.9 0.17 11.4 10.6 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L6e PF01159.19 PVD31322.1 - 1.6e-38 131.6 0.4 1.6e-38 131.6 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e TFIIF_alpha PF05793.12 PVD31323.1 - 0.54 8.8 11.2 0.73 8.4 11.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPX PF03105.19 PVD31323.1 - 1.1 9.1 14.0 2.3 8.0 14.0 1.5 1 1 0 1 1 1 0 SPX domain TPD52 PF04201.15 PVD31324.1 - 0.00078 19.1 5.0 0.0018 17.9 5.0 1.6 1 0 0 1 1 1 1 Tumour protein D52 family Gp-FAR-1 PF05823.12 PVD31324.1 - 0.036 14.4 1.1 0.069 13.5 1.1 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2572 PF10833.8 PVD31324.1 - 0.1 12.4 3.2 12 5.6 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2572) DUF3782 PF12644.7 PVD31324.1 - 0.2 11.9 1.4 0.48 10.6 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) DUF724 PF05266.14 PVD31324.1 - 0.24 11.2 6.0 0.52 10.1 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SieB PF14163.6 PVD31324.1 - 0.39 10.2 3.0 0.29 10.6 1.0 1.8 1 1 1 2 2 2 0 Super-infection exclusion protein B bZIP_1 PF00170.21 PVD31324.1 - 0.43 10.7 7.4 0.07 13.2 3.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF4094 PF13334.6 PVD31324.1 - 1.1 9.8 4.5 2.6 8.5 3.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) MafB19-deam PF14437.6 PVD31325.1 - 2.6e-22 79.1 0.1 3.2e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 PVD31325.1 - 4.5e-21 74.6 1.1 6.6e-21 74.1 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NAD1 PF18778.1 PVD31325.1 - 2.3e-05 24.6 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 PVD31325.1 - 3e-05 24.2 0.1 4.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 PVD31325.1 - 3.2e-05 24.0 0.1 5.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 PVD31325.1 - 3.7e-05 23.8 0.1 5.7e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 APOBEC3 APOBEC_N PF08210.11 PVD31325.1 - 0.00018 21.4 0.1 0.00026 20.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 PVD31325.1 - 0.0016 18.4 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 PVD31325.1 - 0.0028 17.8 0.1 0.0042 17.2 0.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 Inv-AAD PF18785.1 PVD31325.1 - 0.0097 15.8 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 PVD31325.1 - 0.015 15.4 1.9 0.15 12.2 1.7 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase Pyr_redox_2 PF07992.14 PVD31326.1 - 1.2e-47 162.6 0.0 3.1e-47 161.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 PVD31326.1 - 9e-12 45.9 0.1 1.6e-11 45.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox PF00070.27 PVD31326.1 - 2e-07 31.5 0.1 4.5e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Metallophos_2 PF12850.7 PVD31326.1 - 2.3e-05 24.7 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 PVD31326.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Pyr_redox_3 PF13738.6 PVD31326.1 - 0.03 13.6 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3313 PF11769.8 PVD31326.1 - 0.033 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) NAD_binding_9 PF13454.6 PVD31326.1 - 0.038 14.0 0.1 1.4 8.9 0.0 2.5 1 1 1 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 PVD31326.1 - 0.17 10.9 0.4 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sulfotransfer_1 PF00685.27 PVD31327.1 - 2.5e-16 60.0 0.0 3.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31327.1 - 3.3e-12 47.3 0.0 8.1e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 PVD31327.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase domain Rad51 PF08423.11 PVD31328.1 - 2.5e-07 30.2 0.0 3.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 Nudix_hydro PF18290.1 PVD31329.1 - 1e-26 92.7 0.1 1.7e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 PVD31329.1 - 1.5e-22 80.1 0.0 2.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain YabA PF06156.13 PVD31330.1 - 0.0061 17.2 1.0 0.0061 17.2 1.0 5.9 3 1 1 4 4 4 1 Initiation control protein YabA DUF4250 PF14056.6 PVD31330.1 - 0.018 15.0 0.6 0.018 15.0 0.6 5.2 6 1 1 7 7 7 0 Domain of unknown function (DUF4250) DUF1664 PF07889.12 PVD31330.1 - 1.6 8.8 27.8 2.7 8.1 3.3 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) FKBP_N PF01346.18 PVD31330.1 - 4 8.4 10.6 1.1 10.3 0.0 3.4 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TPR_2 PF07719.17 PVD31331.1 - 2.9e-15 55.1 19.2 0.011 15.8 0.2 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31331.1 - 2.2e-14 53.7 11.5 0.0014 19.1 0.0 6.6 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31331.1 - 6.2e-13 48.0 18.1 0.0068 16.2 0.6 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD31331.1 - 9.1e-10 38.5 12.5 0.25 12.3 0.2 7.6 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD31331.1 - 1.1e-09 38.5 14.1 0.026 14.8 0.4 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31331.1 - 1.1e-09 37.7 8.1 0.0032 17.4 0.2 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD31331.1 - 7.7e-09 36.1 8.1 0.57 10.9 0.2 6.2 5 2 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31331.1 - 3.1e-08 33.2 12.0 0.44 10.9 0.1 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD31331.1 - 1.4e-07 31.6 22.3 1.1 9.5 0.1 6.5 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PVD31331.1 - 0.00018 21.9 11.4 19 6.1 0.2 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD31331.1 - 0.00087 19.1 8.8 1.6 8.7 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF4919 PF16266.5 PVD31331.1 - 0.0011 19.0 2.0 0.31 11.0 0.2 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4919) TPR_11 PF13414.6 PVD31331.1 - 0.0014 18.3 2.8 0.47 10.2 0.0 4.8 5 0 0 5 5 5 1 TPR repeat TPR_15 PF13429.6 PVD31331.1 - 0.0046 16.2 4.8 0.47 9.6 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat HECW1_helix PF18436.1 PVD31331.1 - 0.016 15.3 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 ChAPs PF09295.10 PVD31331.1 - 0.029 13.4 0.5 0.24 10.4 0.1 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 PVD31331.1 - 0.072 13.3 7.4 0.27 11.4 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD31331.1 - 0.78 9.8 4.0 1.3 9.1 0.5 3.0 1 1 3 4 4 4 0 Putative TPR-like repeat RPN7 PF10602.9 PVD31331.1 - 2.1 8.0 6.6 5 6.8 0.3 3.4 2 2 0 3 3 3 0 26S proteasome subunit RPN7 PPR PF01535.20 PVD31331.1 - 4.9 7.6 5.2 83 3.8 0.1 4.7 6 0 0 6 6 5 0 PPR repeat PTH2 PF01981.16 PVD31332.1 - 2.7e-47 159.9 0.2 3.6e-47 159.5 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rsm22 PF09243.10 PVD31332.1 - 0.092 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PTS_2-RNA PF01885.16 PVD31333.1 - 1.3e-12 48.2 0.1 3.3e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family LRR_4 PF12799.7 PVD31333.1 - 3.2e-05 24.2 12.5 0.0049 17.2 3.7 3.9 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD31333.1 - 3.6e-05 23.5 5.1 0.6 10.3 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 PVD31333.1 - 0.09 13.4 4.9 79 4.4 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD31333.1 - 0.17 11.7 8.3 6.6 6.6 0.1 3.8 2 1 2 4 4 4 0 Leucine rich repeat NPR3 PF03666.13 PVD31334.1 - 1.4e-38 132.9 4.7 4e-31 108.3 3.0 2.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 PVD31334.1 - 0.0054 15.5 0.4 0.037 12.8 0.1 2.3 2 1 0 2 2 2 1 Nitrogen permease regulator 2 DUF2615 PF11027.8 PVD31335.1 - 1.9e-37 127.6 0.0 2.1e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) LIM PF00412.22 PVD31336.1 - 7.5e-07 29.3 0.6 2.4e-06 27.7 0.6 1.9 1 0 0 1 1 1 1 LIM domain ECH_2 PF16113.5 PVD31336.1 - 0.23 10.9 5.8 0.36 10.3 5.8 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase SieB PF14163.6 PVD31336.1 - 1.6 8.2 3.5 2.6 7.5 3.5 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B CemA PF03040.14 PVD31336.1 - 2.3 8.1 4.5 3.5 7.5 4.5 1.2 1 0 0 1 1 1 0 CemA family DUF2009 PF09418.10 PVD31336.1 - 2.6 7.0 4.6 4.2 6.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) HTH_32 PF13565.6 PVD31336.1 - 6.2 7.5 10.4 1.6 9.4 3.7 2.6 1 1 1 2 2 2 0 Homeodomain-like domain Glyco_transf_21 PF13506.6 PVD31337.1 - 9.5e-48 161.9 0.0 1.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 PVD31337.1 - 2.5e-23 83.2 0.0 3.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PVD31337.1 - 3.8e-08 33.5 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 MGAT2 PF05060.14 PVD31339.1 - 7.4e-103 344.3 3.1 8.6e-103 344.0 3.1 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) ubiquitin PF00240.23 PVD31340.1 - 1.7e-09 37.3 0.0 0.0007 19.3 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin family Ank_2 PF12796.7 PVD31340.1 - 2.7e-05 24.7 0.0 0.00042 20.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD31340.1 - 0.00018 22.0 0.1 0.064 13.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Rad60-SLD PF11976.8 PVD31340.1 - 0.019 14.8 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 PVD31340.1 - 0.079 13.7 0.1 14 6.4 0.0 2.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD MGAT2 PF05060.14 PVD31341.1 - 6.2e-103 344.5 2.8 7.4e-103 344.3 2.8 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) ketoacyl-synt PF00109.26 PVD31342.1 - 7.4e-83 278.0 0.0 1.4e-82 277.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PVD31342.1 - 1.1e-52 178.5 0.0 2.5e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 PVD31342.1 - 1.3e-50 172.7 0.0 2.7e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 PVD31342.1 - 6.1e-33 113.4 0.0 1.4e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 PVD31342.1 - 1.2e-28 100.2 0.0 2.9e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 PVD31342.1 - 1e-14 54.9 0.0 2.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 PVD31342.1 - 9.2e-09 35.0 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 PVD31342.1 - 6.9e-08 32.7 0.1 2.1e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 PVD31342.1 - 2.6e-07 30.4 0.0 5.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 PVD31342.1 - 1.3e-05 24.8 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Condensation PF00668.20 PVD31342.1 - 0.064 11.9 0.0 0.32 9.6 0.0 2.1 2 0 0 2 2 2 0 Condensation domain Nucleoside_tran PF01733.18 PVD31343.1 - 2.2e-51 175.1 14.5 5.9e-32 111.3 0.3 2.5 3 0 0 3 3 3 2 Nucleoside transporter Med19 PF10278.9 PVD31344.1 - 3.1e-60 203.1 11.1 4.5e-60 202.6 11.1 1.2 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 THOC2_N PF16134.5 PVD31344.1 - 0.22 10.1 7.3 0.31 9.6 7.3 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RNA_pol_Rpc4 PF05132.14 PVD31344.1 - 0.74 10.2 9.2 1.2 9.5 9.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 PVD31344.1 - 1.3 9.2 12.6 1.9 8.7 12.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Connexin PF00029.19 PVD31344.1 - 8.4 6.1 6.9 12 5.6 6.9 1.2 1 0 0 1 1 1 0 Connexin V-SNARE_C PF12352.8 PVD31345.1 - 0.0017 18.6 4.0 0.021 15.1 0.1 3.6 2 1 2 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus FapA PF03961.13 PVD31345.1 - 0.071 11.7 1.8 0.091 11.4 1.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4357 PF14267.6 PVD31345.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) PSP PF04046.16 PVD31346.1 - 1.3e-17 63.4 1.6 2.8e-17 62.3 1.6 1.6 1 0 0 1 1 1 1 PSP Castor1_N PF18700.1 PVD31346.1 - 0.08 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Beta_helix PF13229.6 PVD31348.1 - 4.2e-15 55.9 22.5 8.7e-10 38.7 12.4 3.0 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.13 PVD31348.1 - 2.1e-08 33.7 14.4 0.00037 19.8 11.8 3.0 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) SpoU_methylas_C PF12105.8 PVD31348.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal DUF4128 PF13554.6 PVD31348.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function DUF5587 PF17825.1 PVD31348.1 - 0.9 6.7 1.4 1.3 6.2 1.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5587) Beta_helix PF13229.6 PVD31349.1 - 1.2e-10 41.5 19.4 3.1e-09 36.9 12.5 3.2 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.13 PVD31349.1 - 0.00021 20.6 9.6 0.0033 16.7 10.1 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF5587 PF17825.1 PVD31349.1 - 0.72 7.1 1.2 0.98 6.6 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5587) Beta_helix PF13229.6 PVD31350.1 - 1.1e-15 57.8 21.2 4.9e-10 39.5 11.4 3.0 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.13 PVD31350.1 - 2.6e-07 30.2 11.9 0.00056 19.2 8.2 3.0 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF4128 PF13554.6 PVD31350.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function SpoU_methylas_C PF12105.8 PVD31350.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Beta_helix PF13229.6 PVD31351.1 - 2.6e-13 50.1 25.0 6.9e-08 32.5 7.5 2.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 PVD31351.1 - 2.6e-06 26.9 18.2 0.0015 17.9 14.9 2.4 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF4140 PF13600.6 PVD31351.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Beta_helix PF13229.6 PVD31352.1 - 4e-15 56.0 18.8 7.8e-09 35.6 13.1 2.8 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 PVD31352.1 - 2.1e-07 30.5 12.4 0.0021 17.3 8.8 3.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 PVD31352.1 - 0.38 10.6 5.3 0.63 9.8 0.0 2.8 3 0 0 3 3 3 0 Pectate lyase superfamily protein DUF5587 PF17825.1 PVD31352.1 - 0.88 6.8 1.7 1.2 6.3 1.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5587) Ion_trans_2 PF07885.16 PVD31354.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Ion channel Ion_trans_2 PF07885.16 PVD31356.1 - 6e-19 67.8 2.5 9.3e-19 67.2 2.5 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PVD31356.1 - 0.0033 16.7 1.7 0.0048 16.2 1.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD31357.1 - 3.4e-28 97.4 11.5 9.9e-19 67.1 4.0 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 PVD31357.1 - 0.38 10.0 8.3 0.057 12.6 2.7 2.0 2 0 0 2 2 2 0 Ion transport protein UNC-93 PF05978.16 PVD31358.1 - 0.00098 18.9 6.3 0.00098 18.9 6.3 2.5 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sulfotransfer_1 PF00685.27 PVD31359.1 - 2.5e-05 23.9 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain UbiD PF01977.16 PVD31359.1 - 0.088 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Ank_2 PF12796.7 PVD31360.1 - 8.8e-15 55.1 1.9 6.7e-12 45.8 0.5 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD31360.1 - 1.1e-14 54.1 5.7 5.9e-06 26.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD31360.1 - 1.7e-12 46.3 2.4 0.00065 20.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PVD31360.1 - 4e-10 40.0 1.9 0.00035 21.1 0.1 3.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD31360.1 - 8.1e-10 38.8 5.4 0.0045 17.3 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Invas_SpaK PF03519.14 PVD31360.1 - 0.078 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Invasion protein B family Na_sulph_symp PF00939.19 PVD31361.1 - 6.7e-92 309.0 9.9 1.2e-91 308.2 9.9 1.3 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31361.1 - 1.1e-42 146.3 41.4 7.1e-21 74.7 6.0 3.2 2 1 1 3 3 3 3 Citrate transporter Sds3 PF08598.11 PVD31362.1 - 1e-19 71.4 5.0 1.6e-19 70.8 5.0 1.3 1 0 0 1 1 1 1 Sds3-like SpoIIE PF07228.12 PVD31362.1 - 1.5e-14 54.4 0.0 2.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PVD31362.1 - 8e-09 35.5 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PVD31362.1 - 2.2e-08 34.0 0.0 2e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C LCD1 PF09798.9 PVD31362.1 - 0.85 8.1 12.7 0.14 10.6 1.1 2.1 2 0 0 2 2 2 0 DNA damage checkpoint protein DER1 PF04511.15 PVD31363.1 - 2.5e-73 246.1 15.1 2.9e-73 245.9 15.1 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 PVD31363.1 - 0.011 15.4 0.0 0.011 15.4 0.0 2.0 1 1 1 2 2 2 0 Oleosin PI3Ka PF00613.20 PVD31364.1 - 5.9e-29 100.8 0.4 5.1e-28 97.7 0.0 2.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PVD31364.1 - 2e-26 93.4 0.2 6.3e-25 88.4 0.1 2.7 1 1 1 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NADHdh_A3 PF14987.6 PVD31364.1 - 0.11 12.9 0.0 0.39 11.0 0.0 2.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Na_Ca_ex PF01699.24 PVD31365.1 - 3.2e-46 157.0 46.0 6.3e-25 87.9 18.4 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Stathmin PF00836.19 PVD31366.1 - 0.00027 20.9 8.6 0.00048 20.1 8.6 1.4 1 1 0 1 1 1 1 Stathmin family MTP18 PF10558.9 PVD31367.1 - 2.5e-20 73.2 2.3 1.9e-09 37.7 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_62 PF03664.13 PVD31367.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Fig1 PF12351.8 PVD31367.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 BRICHOS PF04089.14 PVD31368.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain PLAT PF01477.23 PVD31369.1 - 1.1e-11 45.4 0.6 2.8e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 PLAT/LH2 domain PKD_channel PF08016.12 PVD31369.1 - 3.6e-08 32.5 0.1 3.6e-08 32.5 0.1 2.8 3 1 0 3 3 3 1 Polycystin cation channel zf-C2H2_4 PF13894.6 PVD31369.1 - 7.4e-05 23.3 27.0 0.12 13.3 1.5 5.6 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD31369.1 - 0.00057 20.1 2.9 0.43 10.9 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PVD31369.1 - 0.0025 18.2 20.0 0.21 12.1 1.4 5.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD31369.1 - 0.0082 15.9 1.1 0.0082 15.9 1.1 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain FOXP-CC PF16159.5 PVD31369.1 - 0.017 15.7 0.3 0.051 14.2 0.3 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain ApoC-I PF04691.12 PVD31369.1 - 0.2 11.6 0.3 0.54 10.2 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) zf-C2H2_2 PF12756.7 PVD31369.1 - 0.57 10.5 4.6 2.2 8.6 4.6 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 PVD31369.1 - 3.1 8.4 14.2 5.1 7.7 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double domain OrsD PF12013.8 PVD31369.1 - 3.9 7.9 8.5 0.51 10.8 0.6 3.0 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D NYD-SP28 PF14772.6 PVD31371.1 - 2.4e-30 104.6 16.7 2.4e-30 104.6 16.7 5.6 2 1 3 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 PVD31371.1 - 1.2e-09 38.1 5.9 1.2e-09 38.1 5.9 4.6 4 0 0 4 4 4 2 Sperm tail C-terminal domain Baculo_PEP_C PF04513.12 PVD31371.1 - 0.43 10.6 12.2 0.54 10.3 1.0 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 PVD31371.1 - 0.87 9.8 37.9 0.077 13.2 6.9 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Cass2 PF14526.6 PVD31371.1 - 1.4 9.1 13.4 0.81 9.8 0.6 4.1 2 2 0 4 4 4 0 Integron-associated effector binding protein DUF948 PF06103.11 PVD31371.1 - 7.7 6.8 8.5 4.8 7.5 0.9 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NUC153 PF08159.12 PVD31372.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.6 3 1 1 4 4 4 0 NUC153 domain Metallophos_2 PF12850.7 PVD31373.1 - 4.7e-15 56.2 0.2 5.6e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PVD31373.1 - 0.051 14.1 0.2 0.083 13.4 0.2 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase FAM216B PF15107.6 PVD31374.1 - 3.4e-06 26.9 0.1 3.4e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 FAM216B protein family HEAT_2 PF13646.6 PVD31375.1 - 9.3e-14 51.6 1.5 1.6e-05 25.2 0.1 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 PVD31375.1 - 2.3e-10 39.8 2.8 0.064 13.5 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 PVD31375.1 - 0.00015 22.2 1.3 3.3 8.3 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 PVD31375.1 - 0.0021 18.1 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 TIR_2 PF13676.6 PVD31375.1 - 0.0029 18.2 0.0 0.0055 17.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 PVD31375.1 - 0.0032 17.5 0.1 6.8 6.9 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 PVD31375.1 - 1.1 10.1 4.2 56 4.8 0.0 4.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Kelch_3 PF13415.6 PVD31376.1 - 7.8e-47 156.8 5.1 4.1e-09 36.5 0.0 7.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD31376.1 - 2.5e-43 145.4 8.2 4.1e-07 29.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PVD31376.1 - 1.1e-40 137.4 8.4 1.2e-07 31.7 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD31376.1 - 4.3e-38 128.4 8.8 8.7e-08 32.2 0.1 6.5 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 PVD31376.1 - 3.7e-36 123.7 0.0 1.4e-19 70.3 0.0 3.2 2 1 1 3 3 3 2 BTB/POZ domain Kelch_5 PF13854.6 PVD31376.1 - 4.7e-35 119.0 6.1 2.1e-06 27.6 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD31376.1 - 3.6e-24 83.7 8.5 5.2e-07 29.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 PVD31376.1 - 7.6e-05 22.8 0.1 0.0043 17.1 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch RAG2 PF03089.14 PVD31376.1 - 0.01 14.9 0.2 0.38 9.7 0.0 3.1 3 2 1 4 4 4 0 Recombination activating protein 2 p450 PF00067.22 PVD31377.1 - 5.2e-100 335.4 0.2 7.5e-100 334.9 0.1 1.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD31378.1 - 1.8e-95 320.4 0.0 2.3e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD31379.1 - 2e-34 119.2 0.1 2.2e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD31380.1 - 5.3e-117 391.4 0.0 6.4e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD31381.1 - 1.9e-63 214.9 0.2 2.1e-63 214.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD31382.1 - 9.5e-99 331.2 0.5 1.1e-97 327.7 0.1 1.9 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD31383.1 - 1.8e-122 409.4 0.0 2.2e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRAL_TRIO PF00650.20 PVD31384.1 - 7.8e-42 142.7 0.1 1.3e-41 142.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 PVD31384.1 - 5.8e-13 49.5 0.1 1.1e-05 26.0 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 PVD31384.1 - 3e-07 30.7 0.0 7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD31384.1 - 7.8e-06 26.0 0.3 1.8e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PEP_mutase PF13714.6 PVD31385.1 - 3.8e-65 219.7 0.0 4.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 PVD31385.1 - 0.00011 20.9 0.0 0.0043 15.6 0.0 2.0 1 1 0 2 2 2 2 Isocitrate lyase family Bac_luciferase PF00296.20 PVD31385.1 - 0.039 13.4 0.5 33 3.8 0.1 3.1 2 1 1 3 3 3 0 Luciferase-like monooxygenase bZIP_1 PF00170.21 PVD31386.1 - 3e-10 40.0 16.2 9.3e-10 38.5 16.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD31386.1 - 2.7e-09 37.0 14.3 2.7e-09 37.0 14.3 2.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD31386.1 - 7.1e-07 29.7 13.5 7.1e-07 29.7 13.5 1.7 2 0 0 2 2 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 PVD31386.1 - 0.00029 20.9 4.9 0.00079 19.5 4.9 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ZapB PF06005.12 PVD31386.1 - 0.0025 18.2 3.0 0.0025 18.2 3.0 2.2 3 0 0 3 3 2 1 Cell division protein ZapB KASH_CCD PF14662.6 PVD31386.1 - 0.0047 16.8 9.8 0.0096 15.8 9.8 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4718 PF15842.5 PVD31386.1 - 0.0047 16.7 2.1 0.0047 16.7 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4718) eIF-6 PF01912.18 PVD31386.1 - 0.03 13.7 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 eIF-6 family NRBF2 PF08961.10 PVD31386.1 - 0.045 13.4 5.5 0.11 12.1 5.5 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator FAM76 PF16046.5 PVD31386.1 - 0.17 11.2 6.4 0.38 10.1 6.4 1.5 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 PVD31386.1 - 0.41 10.5 5.1 0.78 9.5 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 PVD31386.1 - 0.42 11.3 4.8 1.2 9.8 4.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 PVD31386.1 - 0.45 10.3 5.0 1.1 9.1 5.0 1.6 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 PVD31386.1 - 1.8 8.9 8.9 1.6 9.1 4.7 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family Cep57_MT_bd PF06657.13 PVD31386.1 - 2 9.0 9.1 14 6.3 0.1 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 PVD31386.1 - 3.5 8.2 11.6 1.5 9.4 8.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Sulfotransfer_1 PF00685.27 PVD31387.1 - 3.5e-42 144.7 0.5 2e-41 142.2 0.5 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31387.1 - 6.1e-10 39.9 0.1 1.8e-07 31.8 0.1 2.2 1 1 0 2 2 2 2 Sulfotransferase family ColG_sub PF18496.1 PVD31387.1 - 0.049 13.8 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Cu2_monoox_C PF03712.15 PVD31388.1 - 5.2e-25 87.8 1.0 1.4e-24 86.4 1.0 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD31388.1 - 9.5e-25 87.3 0.1 9.5e-25 87.3 0.1 2.1 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF2040 PF09745.9 PVD31391.1 - 2.2e-31 108.4 21.3 2.2e-31 108.4 21.3 3.4 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) ABC2_membrane_3 PF12698.7 PVD31391.1 - 0.26 10.4 0.3 0.39 9.8 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein SNF PF00209.18 PVD31393.1 - 3.7e-221 735.3 33.2 5.7e-221 734.7 33.2 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family IL17 PF06083.11 PVD31394.1 - 7.7e-12 45.5 0.2 1.6e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 Interleukin-17 ORC4_C PF14629.6 PVD31394.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus MFS_1 PF07690.16 PVD31395.1 - 1.3e-35 123.0 47.0 1.8e-31 109.4 24.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD31395.1 - 1.7e-10 40.3 16.7 3.3e-09 36.1 3.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 PVD31395.1 - 0.00025 20.5 5.3 0.00025 20.5 5.3 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 PVD31396.1 - 1.6e-64 217.8 0.0 9e-64 215.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31396.1 - 1.1e-28 100.3 0.0 1.9e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 PVD31396.1 - 2e-17 63.6 3.9 6.1e-17 62.0 3.9 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 PVD31396.1 - 0.00018 22.0 0.1 0.00037 20.9 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 PVD31396.1 - 0.00092 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD31396.1 - 0.05 12.4 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YiiD_C PF09500.10 PVD31396.1 - 0.3 10.9 1.0 37 4.1 0.1 3.2 3 0 0 3 3 3 0 Putative thioesterase (yiiD_Cterm) SET PF00856.28 PVD31402.1 - 1.9e-18 67.4 0.5 1.9e-18 67.4 0.5 5.0 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 PVD31402.1 - 1.8e-08 34.1 0.1 4.4e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 PVD31402.1 - 4e-07 30.3 3.0 4e-07 30.3 3.0 6.1 5 2 1 6 6 6 2 COMPASS (Complex proteins associated with Set1p) component N NHL PF01436.21 PVD31404.1 - 2.9e-07 30.2 7.7 0.0026 17.7 0.1 4.3 4 0 0 4 4 4 2 NHL repeat zf-B_box PF00643.24 PVD31405.1 - 0.14 12.3 8.8 0.23 11.7 8.8 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF948 PF06103.11 PVD31405.1 - 3.6 7.9 6.6 2.7e+02 1.9 6.6 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_12 PF13087.6 PVD31406.1 - 1.4e-48 165.2 0.0 2.6e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PVD31406.1 - 1.1e-23 84.3 0.3 3.6e-13 49.9 0.0 2.8 2 1 1 3 3 3 2 AAA domain Dna2 PF08696.11 PVD31406.1 - 3.5e-22 79.2 1.5 2.1e-18 66.9 0.4 2.6 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_30 PF13604.6 PVD31406.1 - 1.8e-09 37.6 0.0 7.8e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD31406.1 - 9.8e-07 29.2 0.0 6.3e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PVD31406.1 - 0.0016 17.7 0.0 0.0086 15.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 PVD31406.1 - 0.052 13.9 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 PVD31406.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.6 PVD31406.1 - 0.08 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PVD31406.1 - 0.088 12.5 0.1 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 PVD31406.1 - 0.11 12.6 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF83 Helicase_RecD PF05127.14 PVD31406.1 - 0.11 12.3 0.0 0.57 10.0 0.0 2.2 2 1 0 2 2 2 0 Helicase CbiA PF01656.23 PVD31406.1 - 0.15 12.1 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arm PF00514.23 PVD31408.1 - 1.2e-33 114.1 19.7 7.4e-06 25.8 0.0 9.2 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 PVD31408.1 - 2.4e-12 46.2 2.1 4.5e-12 45.3 2.1 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 PVD31408.1 - 2.2e-10 40.8 0.2 0.091 13.2 0.0 5.3 4 2 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 PVD31408.1 - 1.8e-06 28.3 11.8 0.0073 16.8 0.0 5.4 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.22 PVD31408.1 - 1.9e-06 27.6 9.8 1 9.8 0.2 7.3 8 0 0 8 8 8 1 HEAT repeat V-ATPase_H_N PF03224.14 PVD31408.1 - 1.3e-05 24.7 0.3 0.0013 18.1 0.0 2.4 2 1 0 2 2 2 1 V-ATPase subunit H IBB PF01749.20 PVD31408.1 - 1.6e-05 25.2 2.4 1.6e-05 25.2 2.4 2.1 2 0 0 2 2 2 1 Importin beta binding domain RICTOR_V PF14668.6 PVD31408.1 - 0.0034 17.6 1.2 0.6 10.4 0.0 4.2 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 PVD31408.1 - 0.0072 16.3 0.2 12 5.8 0.1 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3361) SAPS PF04499.15 PVD31408.1 - 0.053 12.3 0.2 0.27 10.0 0.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HEAT_PBS PF03130.16 PVD31408.1 - 6 7.8 14.7 1.6 9.6 0.1 5.7 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat MazG-like PF12643.7 PVD31409.1 - 5.8e-14 52.1 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 PVD31409.1 - 4.9e-06 26.6 0.1 1.7e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.11 PVD31409.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 dUTPase PspB PF06667.12 PVD31410.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B DUF4381 PF14316.6 PVD31410.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PSI PF01437.25 PVD31410.1 - 0.39 11.3 4.8 6.6 7.4 4.8 2.4 1 1 0 1 1 1 0 Plexin repeat EMI PF07546.13 PVD31410.1 - 0.49 11.2 10.3 0.14 13.0 6.7 2.0 2 0 0 2 2 2 0 EMI domain Lectin_C PF00059.21 PVD31411.1 - 0.00017 22.3 0.0 0.00027 21.6 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Mago-bind PF09282.10 PVD31411.1 - 0.23 11.3 0.7 0.53 10.2 0.1 1.9 2 0 0 2 2 2 0 Mago binding RVP PF00077.20 PVD31414.1 - 9.6e-06 25.8 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 PVD31414.1 - 0.047 14.3 0.0 0.094 13.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ubie_methyltran PF01209.18 PVD31415.1 - 1.2e-31 109.9 0.0 1.5e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PVD31415.1 - 3.7e-12 46.7 0.0 6.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD31415.1 - 2e-08 34.8 0.0 4.5e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD31415.1 - 0.0054 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRAPPC9-Trs120 PF08626.11 PVD31415.1 - 0.046 11.1 0.1 0.05 11.0 0.1 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Methyltransf_12 PF08242.12 PVD31415.1 - 0.047 14.4 0.0 0.082 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MGC-24 PF05283.11 PVD31415.1 - 0.074 13.5 0.9 0.11 13.0 0.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPR_5 PF12688.7 PVD31415.1 - 0.093 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Ubie_methyltran PF01209.18 PVD31416.1 - 3e-84 282.0 0.0 5.7e-84 281.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PVD31416.1 - 1.6e-18 67.1 0.0 3.4e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD31416.1 - 4.8e-16 59.2 0.0 1.5e-15 57.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD31416.1 - 5.4e-09 36.0 0.0 1.4e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD31416.1 - 9.2e-07 29.5 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD31416.1 - 0.00035 20.4 0.0 0.00059 19.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PVD31416.1 - 0.013 15.4 0.0 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 PVD31416.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 PVD31416.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 PVD31416.1 - 0.078 13.0 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF4042 PF13251.6 PVD31417.1 - 3.3e-49 167.0 10.1 5.8e-32 110.9 0.9 4.2 3 2 1 4 4 4 2 Domain of unknown function (DUF4042) HEAT PF02985.22 PVD31417.1 - 2.3e-10 39.8 16.4 0.021 15.1 0.1 8.2 9 0 0 9 9 8 4 HEAT repeat HEAT_2 PF13646.6 PVD31417.1 - 1e-09 38.6 3.0 0.015 15.7 0.1 6.3 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 PVD31417.1 - 3.8e-07 30.5 9.3 0.034 14.7 0.3 6.8 5 1 3 8 8 8 3 HEAT-like repeat Arm PF00514.23 PVD31417.1 - 1.4e-05 25.0 10.4 0.02 15.0 0.2 5.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PVD31417.1 - 0.0034 16.0 12.5 0.067 11.7 0.3 3.7 3 1 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 PVD31417.1 - 0.0069 16.6 1.6 1.2 9.3 0.1 3.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 PVD31417.1 - 0.03 14.6 0.4 6.2 7.2 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DNA_pol3_gamma3 PF12169.8 PVD31417.1 - 0.036 14.0 1.3 0.21 11.5 0.2 2.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Tti2 PF10521.9 PVD31417.1 - 0.061 12.9 0.1 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Tti2 family Cnd1 PF12717.7 PVD31417.1 - 2.3 8.2 9.9 5.9 6.9 0.1 4.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ANTH PF07651.16 PVD31418.1 - 3.4e-62 210.0 0.0 3.4e-62 210.0 0.0 4.4 3 1 0 4 4 4 2 ANTH domain I_LWEQ PF01608.17 PVD31418.1 - 4.7e-52 176.3 5.7 4.7e-52 176.3 5.7 7.0 4 1 3 7 7 7 1 I/LWEQ domain PX PF00787.24 PVD31418.1 - 0.23 11.5 3.3 16 5.5 0.1 3.8 3 0 0 3 3 3 0 PX domain Baculo_PEP_C PF04513.12 PVD31418.1 - 0.26 11.3 41.8 0.17 11.9 5.0 5.9 6 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus BCL9 PF11502.8 PVD31418.1 - 2.4 8.0 8.0 4.1 7.3 2.2 3.8 3 0 0 3 3 3 0 B-cell lymphoma 9 protein DUF1589 PF07628.11 PVD31419.1 - 0.068 13.3 0.2 0.071 13.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) Ion_trans PF00520.31 PVD31420.1 - 9.3e-13 48.0 20.2 1.2e-12 47.6 20.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ran_BP1 PF00638.18 PVD31421.1 - 6.1e-28 97.5 1.9 8.9e-28 97.0 1.9 1.3 1 0 0 1 1 1 1 RanBP1 domain AAA_25 PF13481.6 PVD31422.1 - 1.8e-24 86.4 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain tRNA_U5-meth_tr PF05958.11 PVD31422.1 - 9.6e-17 61.0 2.0 4.1e-16 58.9 0.5 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PVD31422.1 - 5.4e-11 42.5 0.3 1.1e-10 41.5 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD31422.1 - 9e-10 39.1 0.2 2.7e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain DnaB_C PF03796.15 PVD31422.1 - 3.5e-08 33.1 0.0 9e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain MTS PF05175.14 PVD31422.1 - 4e-07 29.7 0.1 8.2e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PVD31422.1 - 4.6e-06 26.2 0.1 8.5e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.10 PVD31422.1 - 5.3e-06 26.1 0.3 1.1e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase ATPase PF06745.13 PVD31422.1 - 9.9e-06 25.1 0.0 3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 KaiC Methyltransf_32 PF13679.6 PVD31422.1 - 1.2e-05 25.3 0.4 2.5e-05 24.3 0.4 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PVD31422.1 - 2.5e-05 24.0 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 PVD31422.1 - 6e-05 22.5 0.3 0.00012 21.5 0.3 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PVD31422.1 - 8.5e-05 22.1 0.4 0.00016 21.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 PVD31422.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 PVD31422.1 - 0.00018 22.1 0.1 0.0004 21.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain AAA_16 PF13191.6 PVD31422.1 - 0.00037 20.9 0.0 0.0013 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Methyltransf_23 PF13489.6 PVD31422.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AAA_29 PF13555.6 PVD31422.1 - 0.0012 18.5 0.1 0.0082 15.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 PVD31422.1 - 0.0017 18.7 0.1 0.0068 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain N6_N4_Mtase PF01555.18 PVD31422.1 - 0.0042 16.8 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 DNA methylase AAA_23 PF13476.6 PVD31422.1 - 0.0056 17.2 0.1 0.013 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain Methyltransf_18 PF12847.7 PVD31422.1 - 0.01 15.7 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain T2SSE PF00437.20 PVD31422.1 - 0.013 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AviRa PF11599.8 PVD31422.1 - 0.028 13.9 0.4 0.058 12.8 0.4 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa CMAS PF02353.20 PVD31422.1 - 0.054 12.8 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 PVD31422.1 - 0.09 12.5 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Lysine methyltransferase ABC_tran PF00005.27 PVD31422.1 - 0.11 13.0 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 PVD31422.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GMP_PDE_delta PF05351.11 PVD31423.1 - 1.7e-70 236.2 1.5 2.5e-70 235.6 1.5 1.3 1 0 0 1 1 1 1 GMP-PDE, delta subunit Glyco_transf_22 PF03901.17 PVD31425.1 - 4e-19 69.2 3.3 6.5e-19 68.5 3.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TPR_16 PF13432.6 PVD31425.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31425.1 - 0.078 13.1 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 PVD31426.1 - 4.1e-07 29.6 5.2 1.3e-05 24.6 0.3 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Mog1 PF04603.12 PVD31427.1 - 1.6e-37 129.0 0.0 2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rhodanese PF00581.20 PVD31428.1 - 6.6e-07 29.8 0.0 1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 PVD31428.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ldh_1_C PF02866.18 PVD31429.1 - 3.7e-53 179.9 0.0 5e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PVD31429.1 - 3.4e-16 59.6 0.1 6.4e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain IFT20 PF14931.6 PVD31430.1 - 3.2e-41 140.2 5.6 3.9e-41 140.0 5.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 RhoGEF PF00621.20 PVD31430.1 - 0.009 16.3 0.3 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 RhoGEF domain Fib_alpha PF08702.10 PVD31430.1 - 0.27 11.4 4.5 1.5 9.0 0.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1635 PF07795.11 PVD31430.1 - 2.6 7.9 6.2 1.9 8.3 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) BTB_2 PF02214.22 PVD31431.1 - 4e-11 43.1 0.0 7.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.22 PVD31432.1 - 3.9e-14 52.2 0.0 6.9e-12 45.0 0.0 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.27 PVD31432.1 - 5.8e-13 48.9 0.2 3.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain RRM_3 PF08777.11 PVD31432.1 - 0.0089 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Sulfotransfer_3 PF13469.6 PVD31432.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family 2OG-FeII_Oxy_3 PF13640.6 PVD31433.1 - 8.2e-09 36.2 0.0 2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 PVD31433.1 - 0.0017 18.3 0.0 0.49 10.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 PVD31433.1 - 0.0081 16.6 0.0 0.072 13.6 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 PVD31434.1 - 9.1e-78 261.3 0.2 1.3e-77 260.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PVD31434.1 - 1.7e-21 76.6 0.6 8.2e-21 74.4 0.0 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 PVD31434.1 - 1.5e-16 60.9 0.1 1.7e-09 37.7 0.2 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 PVD31434.1 - 9.5e-13 48.4 1.8 1.9e-09 37.8 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD31434.1 - 1.3e-12 46.3 1.2 6.7e-06 25.3 0.5 3.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD31434.1 - 8.1e-11 41.0 0.9 0.00029 20.5 0.3 4.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PVD31434.1 - 1.2e-07 31.5 2.2 0.44 10.4 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD31434.1 - 6.5e-07 28.6 7.7 0.00016 21.0 0.2 3.2 3 0 0 3 3 3 2 EF hand Ubiquitin_3 PF14836.6 PVD31434.1 - 1.7e-05 24.7 0.1 4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3439 PF11921.8 PVD31434.1 - 0.2 11.7 4.8 0.49 10.4 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DJ-1_PfpI PF01965.24 PVD31435.1 - 2.2e-17 63.4 0.0 2.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Ras PF00071.22 PVD31436.1 - 3.5e-31 108.0 0.0 4.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31436.1 - 5.2e-22 78.3 0.0 7.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31436.1 - 4.5e-05 23.0 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD31436.1 - 0.00046 20.2 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 PVD31436.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 PVD31436.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PVD31436.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD31436.1 - 0.049 13.9 0.1 0.099 12.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 PVD31436.1 - 0.051 12.7 0.0 1.4 8.0 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Ras PF00071.22 PVD31437.1 - 1.6e-25 89.6 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31437.1 - 2.1e-13 50.5 0.1 5e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31437.1 - 0.0037 16.7 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD31437.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain QRPTase_C PF01729.19 PVD31438.1 - 5.9e-26 91.2 0.3 8e-26 90.8 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 PVD31438.1 - 0.00051 20.1 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Methyltransf_30 PF05430.11 PVD31438.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Ribul_P_3_epim PF00834.19 PVD31438.1 - 0.14 11.5 0.4 4.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family BRAP2 PF07576.12 PVD31439.1 - 1.7e-23 82.7 0.2 3.3e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 PVD31439.1 - 1e-21 77.0 5.0 3.7e-21 75.2 5.0 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 PVD31439.1 - 1.5e-08 34.8 6.8 1.5e-08 34.8 6.8 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD31439.1 - 1.6e-07 31.0 6.1 5.6e-07 29.3 6.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD31439.1 - 4.6e-06 26.4 4.6 1.7e-05 24.6 4.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD31439.1 - 4.8e-05 23.5 5.0 4.8e-05 23.5 5.0 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD31439.1 - 6.3e-05 22.9 4.0 6.3e-05 22.9 4.0 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD31439.1 - 0.00012 22.1 5.5 0.00036 20.5 4.6 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 PVD31439.1 - 0.00013 21.6 4.6 0.00061 19.5 4.6 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PVD31439.1 - 0.025 14.6 3.8 0.065 13.3 3.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 PVD31439.1 - 0.099 12.4 2.8 0.31 10.8 0.7 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger MnmE_helical PF12631.7 PVD31439.1 - 0.14 12.3 6.3 0.26 11.4 6.3 1.3 1 0 0 1 1 1 0 MnmE helical domain DUF1204 PF06721.11 PVD31439.1 - 0.23 10.9 6.9 0.53 9.7 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Baculo_PEP_C PF04513.12 PVD31439.1 - 0.36 10.9 8.4 0.44 10.6 5.8 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_3 PF13920.6 PVD31439.1 - 0.66 9.9 16.8 0.44 10.5 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.8 PVD31439.1 - 1.6 7.9 12.5 9.8 5.4 12.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 PVD31439.1 - 1.7 8.7 30.1 0.02 14.9 22.3 1.7 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 PVD31439.1 - 2.1 7.2 6.2 3.7 6.3 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1993 PF09351.10 PVD31439.1 - 2.2 8.4 7.9 7.1 6.7 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) zf-C3H2C3 PF17122.5 PVD31439.1 - 5 7.2 9.5 0.057 13.5 1.3 2.1 2 0 0 2 2 1 0 Zinc-finger Tup_N PF08581.10 PVD31439.1 - 5.9 7.3 12.9 6.5 7.1 1.4 2.5 1 1 1 2 2 2 0 Tup N-terminal Spc7 PF08317.11 PVD31439.1 - 6.5 5.5 20.3 2.7 6.8 4.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein cwf21 PF08312.12 PVD31439.1 - 8.1 6.7 12.0 0.74 10.0 1.9 3.2 2 1 0 2 2 2 0 cwf21 domain 5HT_transport_N PF03491.13 PVD31440.1 - 0.097 12.9 0.1 0.73 10.1 0.1 2.1 1 1 1 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Sulfotransfer_1 PF00685.27 PVD31441.1 - 7.8e-53 179.7 0.8 4.6e-51 173.8 0.8 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31441.1 - 3.6e-05 24.3 0.1 0.00013 22.4 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family DUF4184 PF13803.6 PVD31441.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) DUF953 PF06110.11 PVD31443.1 - 4.5e-39 132.7 0.3 9.6e-38 128.5 0.3 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 PVD31443.1 - 0.063 13.1 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Glyco_transf_92 PF01697.27 PVD31444.1 - 3.6e-11 43.2 0.0 6.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 SH3_2 PF07653.17 PVD31445.1 - 1.5e-27 95.0 0.0 5.1e-08 32.5 0.0 4.0 3 1 1 4 4 4 3 Variant SH3 domain SH3_9 PF14604.6 PVD31445.1 - 9e-27 92.7 2.0 2.8e-10 39.9 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 PVD31445.1 - 6.2e-14 51.3 0.2 0.0024 17.4 0.0 4.0 3 0 0 3 3 3 3 SH3 domain fn3 PF00041.21 PVD31445.1 - 7.1e-09 35.9 0.8 0.00054 20.3 0.1 4.8 3 1 0 3 3 3 2 Fibronectin type III domain SUIM_assoc PF16619.5 PVD31445.1 - 0.0013 18.7 7.2 0.0013 18.7 7.2 5.8 6 1 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 SOGA PF11365.8 PVD31445.1 - 0.0025 18.9 10.9 0.0025 18.9 10.9 9.0 5 3 4 9 9 9 1 Protein SOGA bZIP_1 PF00170.21 PVD31445.1 - 0.0037 17.3 6.4 0.0037 17.3 6.4 10.6 6 3 6 12 12 12 4 bZIP transcription factor Glyco_hydro_44 PF12891.7 PVD31445.1 - 0.0047 16.9 1.5 0.016 15.1 1.5 1.9 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Pur_ac_phosph_N PF16656.5 PVD31445.1 - 0.08 13.5 0.0 0.91 10.1 0.0 2.8 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Na_sulph_symp PF00939.19 PVD31446.1 - 1.8e-76 258.1 21.1 9.5e-48 163.4 6.8 2.0 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31446.1 - 1.1e-39 136.4 22.1 2e-22 79.7 5.2 2.3 2 0 0 2 2 2 2 Citrate transporter DctM PF06808.12 PVD31446.1 - 4.8e-05 22.4 6.7 4.8e-05 22.4 6.7 2.9 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component DSPc PF00782.20 PVD31447.1 - 4.4e-35 120.4 0.1 8.8e-35 119.4 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 PVD31447.1 - 1.5e-06 28.0 0.4 3.4e-06 26.9 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 PVD31447.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GAF PF01590.26 PVD31448.1 - 2.2e-06 28.3 0.0 0.00013 22.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain Dpy-30 PF05186.13 PVD31448.1 - 5.2e-05 22.8 1.5 0.038 13.7 0.2 3.0 2 0 0 2 2 2 2 Dpy-30 motif EF-hand_6 PF13405.6 PVD31448.1 - 9.3e-05 22.1 5.8 0.00023 20.8 0.1 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 PVD31448.1 - 0.00031 20.1 0.2 0.00031 20.1 0.2 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 PVD31448.1 - 0.0005 20.5 2.2 0.061 13.8 0.0 4.1 4 1 0 4 4 4 1 EF-hand domain pair Pan3_PK PF18101.1 PVD31448.1 - 0.05 13.6 0.7 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Pan3 Pseudokinase domain EF-hand_8 PF13833.6 PVD31448.1 - 1.3 9.0 6.4 0.13 12.1 0.3 2.7 3 0 0 3 3 3 0 EF-hand domain pair RNA_binding PF01877.17 PVD31448.1 - 9.4 6.5 9.6 3.8 7.8 0.1 3.8 4 0 0 4 4 4 0 RNA binding Na_sulph_symp PF00939.19 PVD31450.1 - 2.8e-78 264.1 28.7 1.5e-74 251.8 12.2 2.6 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31450.1 - 1.6e-22 80.1 13.6 6.3e-19 68.3 6.4 4.1 3 1 1 4 4 4 2 Citrate transporter Na_sulph_symp PF00939.19 PVD31451.1 - 3.6e-97 326.4 17.6 4.7e-97 326.0 17.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31451.1 - 9.4e-39 133.4 47.8 5.4e-17 61.9 2.2 3.2 2 1 1 3 3 3 3 Citrate transporter Glycos_transf_1 PF00534.20 PVD31454.1 - 1.4e-14 54.0 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD31454.1 - 1.1e-12 48.6 0.0 1.9e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PVD31454.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Biotin_lipoyl PF00364.22 PVD31454.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF4416 PF14385.6 PVD31454.1 - 0.039 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Ras PF00071.22 PVD31455.1 - 0.00059 19.5 0.0 0.00072 19.2 0.0 1.1 1 0 0 1 1 1 1 Ras family DDE_Tnp_4 PF13359.6 PVD31456.1 - 8.8e-13 48.2 0.0 2.4e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PVD31456.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain CBM_14 PF01607.24 PVD31457.1 - 2.5e-17 62.8 15.7 6.9e-09 35.7 5.7 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Myb_DNA-bind_5 PF13873.6 PVD31457.1 - 6.4e-11 42.2 4.6 6.4e-11 42.2 4.6 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PVD31457.1 - 0.00018 21.8 3.1 0.00042 20.7 3.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 PVD31457.1 - 0.022 15.0 1.1 0.046 13.9 1.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain CBM_14 PF01607.24 PVD31458.1 - 1.4e-13 50.8 15.5 2e-09 37.5 5.5 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD31459.1 - 6.6e-20 71.0 12.6 1.4e-11 44.4 4.7 2.5 1 1 0 2 2 2 2 Chitin binding Peritrophin-A domain NatB_MDM20 PF09797.9 PVD31460.1 - 3.1e-80 270.0 2.8 7.6e-58 196.3 0.1 2.9 3 0 0 3 3 3 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 PVD31460.1 - 2e-11 44.2 6.3 0.024 15.1 0.4 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD31460.1 - 1.4e-06 28.6 1.3 0.021 15.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD31460.1 - 5.3e-06 26.8 10.3 0.41 11.6 0.0 6.5 4 1 3 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 PVD31460.1 - 1e-05 24.7 0.2 1e-05 24.7 0.2 2.7 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 PVD31460.1 - 4.3e-05 24.1 0.3 1.3 9.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31460.1 - 0.00011 22.0 5.7 0.0086 16.1 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31460.1 - 0.0027 17.6 0.0 0.61 10.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 PVD31460.1 - 0.016 15.7 3.3 0.58 10.6 0.4 3.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 PVD31460.1 - 0.083 12.1 6.8 0.85 8.8 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPPII_N PF12583.8 PVD31460.1 - 0.17 12.5 0.3 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_12 PF13424.6 PVD31460.1 - 0.18 12.2 6.3 12 6.3 0.4 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD31460.1 - 0.47 10.6 2.4 55 3.9 0.0 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 PVD31460.1 - 1.3 9.3 12.2 6.5 7.1 0.1 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PVD31460.1 - 9.4 6.9 7.7 1.3e+02 3.3 0.4 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Surp PF01805.20 PVD31461.1 - 1.3e-30 105.1 1.9 5.1e-16 58.4 0.3 2.8 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 PVD31461.1 - 3.1e-30 105.2 1.4 3.1e-30 105.2 1.4 5.1 4 1 0 4 4 4 1 Alternative splicing regulator PNISR PF15996.5 PVD31461.1 - 0.001 19.4 6.3 0.001 19.4 6.3 5.1 3 2 2 5 5 5 1 Arginine/serine-rich protein PNISR Vma12 PF11712.8 PVD31462.1 - 1.3e-16 60.9 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase CDPS PF16715.5 PVD31462.1 - 0.019 14.6 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase PseudoU_synth_2 PF00849.22 PVD31463.1 - 2.3e-30 105.8 1.0 4.6e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF5320 PF17253.2 PVD31465.1 - 2.5 9.2 15.2 3.3 8.8 7.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ion_trans PF00520.31 PVD31469.1 - 3.2e-15 56.0 5.3 9.8e-15 54.4 5.3 1.8 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD31469.1 - 4.4e-08 33.0 5.4 4.4e-08 33.0 5.4 2.5 2 1 0 2 2 2 1 Ion channel PKD_channel PF08016.12 PVD31469.1 - 4.9e-05 22.2 1.5 0.051 12.2 0.1 2.0 2 0 0 2 2 2 2 Polycystin cation channel SecE PF00584.20 PVD31469.1 - 1.7 8.6 10.0 5.3 7.1 2.8 2.6 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex BLOC1_2 PF10046.9 PVD31471.1 - 0.15 12.3 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CBM_14 PF01607.24 PVD31472.1 - 8.6e-18 64.3 19.0 3.2e-10 40.0 7.6 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain DUF2457 PF10446.9 PVD31477.1 - 9.7 5.2 11.1 11 5.0 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IP_trans PF02121.18 PVD31481.1 - 6.3e-113 376.4 0.1 9.2e-113 375.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 PVD31481.1 - 1.5e-39 136.5 0.9 1.2e-38 133.5 0.0 2.6 2 0 0 2 2 2 1 DDHD domain LNS2 PF08235.13 PVD31481.1 - 6.5e-05 22.5 0.1 0.0017 17.9 0.1 2.3 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hamartin PF04388.12 PVD31481.1 - 3.2 6.3 7.8 6.9 5.2 7.8 1.4 1 0 0 1 1 1 0 Hamartin protein DEK_C PF08766.11 PVD31482.1 - 4.6e-06 26.5 1.7 9.1e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 DEK C terminal domain CHZ PF09649.10 PVD31482.1 - 1.8e-05 24.1 0.1 4.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone domain CHZ RAG1_imp_bd PF12560.8 PVD31482.1 - 0.012 15.2 1.0 0.023 14.3 1.0 1.4 1 0 0 1 1 1 0 RAG1 importin binding TFIIF_alpha PF05793.12 PVD31482.1 - 0.027 13.1 16.3 0.029 13.0 16.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Septin PF00735.18 PVD31483.1 - 1.5e-110 368.9 0.1 2.6e-110 368.1 0.1 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 PVD31483.1 - 0.0015 18.1 0.1 1.4 8.4 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Spc7 PF08317.11 PVD31483.1 - 0.052 12.4 3.5 0.1 11.5 2.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3552 PF12072.8 PVD31483.1 - 0.059 12.8 5.0 0.11 11.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) UBA_e1_thiolCys PF10585.9 PVD31483.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Septin PF00735.18 PVD31484.1 - 7.5e-122 406.0 1.1 1.1e-121 405.5 1.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 PVD31484.1 - 3.7e-09 36.7 0.5 1.6e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD31484.1 - 4.2e-07 30.0 0.2 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PVD31484.1 - 6.1e-06 25.9 2.6 0.0031 17.1 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PVD31484.1 - 4.4e-05 22.9 0.0 0.00012 21.5 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 PVD31484.1 - 7.4e-05 22.4 1.4 0.00014 21.6 0.0 2.1 2 1 1 3 3 3 1 Ras family Roc PF08477.13 PVD31484.1 - 0.0004 20.6 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 PVD31484.1 - 0.00056 20.5 2.0 0.011 16.2 2.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 PVD31484.1 - 0.0015 18.3 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 PVD31484.1 - 0.0024 17.9 6.1 0.49 10.4 0.1 3.0 2 1 0 3 3 3 2 Dynamin family ABC_tran PF00005.27 PVD31484.1 - 0.0028 18.1 2.5 0.0032 18.0 0.3 2.1 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PVD31484.1 - 0.0085 16.5 0.1 0.021 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 PVD31484.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD31484.1 - 0.016 15.5 2.5 0.025 14.9 0.0 2.6 3 2 0 3 3 3 0 AAA domain FeoB_N PF02421.18 PVD31484.1 - 0.019 14.5 0.1 0.081 12.5 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PEP-utilisers_N PF05524.13 PVD31484.1 - 0.019 15.1 0.9 3.9 7.7 0.1 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal AAA_29 PF13555.6 PVD31484.1 - 0.03 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 PVD31484.1 - 0.056 13.7 0.0 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PVD31484.1 - 0.15 12.4 0.1 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 PVD31484.1 - 0.3 10.8 2.5 0.42 10.3 0.4 2.4 2 1 0 2 2 2 0 AAA domain cwf21 PF08312.12 PVD31485.1 - 6.1e-15 55.1 2.4 2e-14 53.5 2.4 2.0 1 0 0 1 1 1 1 cwf21 domain SRRM_C PF15230.6 PVD31485.1 - 1.6e-10 41.4 32.0 1.6e-10 41.4 32.0 9.5 3 1 5 8 8 8 1 Serine/arginine repetitive matrix protein C-terminus HTH_12 PF08461.10 PVD31485.1 - 0.039 13.9 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Peptidase_C2 PF00648.21 PVD31487.1 - 3.5e-104 348.0 0.1 4.4e-104 347.7 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD31487.1 - 4e-39 134.1 0.0 6.2e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III CTX_RstB PF07459.11 PVD31488.1 - 0.14 12.4 1.2 1.1 9.6 0.8 2.2 2 0 0 2 2 2 0 CTX phage RstB protein Serglycin PF04360.12 PVD31489.1 - 0.049 13.6 1.6 0.086 12.8 1.6 1.4 1 0 0 1 1 1 0 Serglycin Nup88 PF10168.9 PVD31490.1 - 2.4e-44 151.3 26.0 2.6e-44 151.2 26.0 1.0 1 0 0 1 1 1 1 Nuclear pore component Spc7 PF08317.11 PVD31490.1 - 0.0028 16.6 7.9 0.0028 16.6 7.9 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein APG17 PF04108.12 PVD31490.1 - 0.0039 16.4 5.3 0.0039 16.4 5.3 2.4 1 1 1 2 2 2 1 Autophagy protein Apg17 Lectin_N PF03954.14 PVD31490.1 - 0.0067 16.2 8.4 0.012 15.3 5.6 2.2 1 1 1 2 2 2 2 Hepatic lectin, N-terminal domain DivIVA PF05103.13 PVD31490.1 - 0.013 15.6 4.7 0.013 15.6 4.7 2.5 1 1 1 2 2 2 0 DivIVA protein YtxH PF12732.7 PVD31490.1 - 0.027 15.0 2.6 2.3 8.8 0.8 2.4 2 1 0 2 2 2 0 YtxH-like protein Bacillus_HBL PF05791.11 PVD31490.1 - 0.029 14.2 10.7 0.041 13.7 8.4 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF725 PF05267.12 PVD31490.1 - 0.049 13.6 1.3 0.1 12.6 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF725) Noelin-1 PF12308.8 PVD31490.1 - 0.065 13.2 10.7 0.15 12.1 3.0 2.9 1 1 2 3 3 3 0 Neurogenesis glycoprotein CLZ PF16526.5 PVD31490.1 - 0.13 12.6 17.1 0.087 13.2 3.8 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IFT57 PF10498.9 PVD31490.1 - 0.21 10.5 21.6 0.041 12.8 14.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 STAT_alpha PF01017.20 PVD31490.1 - 0.21 11.5 19.4 0.025 14.5 5.9 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain TMPIT PF07851.13 PVD31490.1 - 0.28 10.4 14.2 0.13 11.5 11.4 1.8 1 1 1 2 2 2 0 TMPIT-like protein O-FucT PF10250.9 PVD31490.1 - 0.43 10.2 4.0 0.54 9.9 4.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DUF3450 PF11932.8 PVD31490.1 - 0.54 9.5 20.4 0.15 11.3 6.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FliJ PF02050.16 PVD31490.1 - 0.73 10.1 25.9 0.17 12.1 3.9 3.1 1 1 2 3 3 3 0 Flagellar FliJ protein UPF0242 PF06785.11 PVD31490.1 - 0.89 9.6 29.7 0.27 11.3 22.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 PVD31490.1 - 1.5 6.7 11.5 2 6.3 11.5 1.3 1 0 0 1 1 1 0 Prominin DUF16 PF01519.16 PVD31490.1 - 1.9 9.0 23.4 2.4 8.7 6.6 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 MPS2 PF17060.5 PVD31490.1 - 3.6 6.8 18.6 4.7 6.4 18.6 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Laminin_II PF06009.12 PVD31490.1 - 4.5 7.3 14.5 1.5 8.8 7.9 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PVD31490.1 - 4.6 7.3 16.5 0.64 10.1 6.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 PVD31490.1 - 6.2 6.4 11.2 26 4.3 11.1 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 PVD31490.1 - 7.4 7.1 29.6 4.7 7.7 4.2 2.4 1 1 2 3 3 3 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 PVD31490.1 - 8.1 5.9 17.9 17 4.9 17.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 PVD31490.1 - 9.6 5.0 9.6 12 4.7 9.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nup88 PF10168.9 PVD31491.1 - 6.2e-86 288.8 2.5 1.5e-48 165.2 0.1 2.0 1 1 1 2 2 2 2 Nuclear pore component Capsid_VP7 PF17071.5 PVD31491.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 1 1 1 2 2 2 0 Outer capsid protein VP7 CUT PF02376.15 PVD31493.1 - 8.7e-77 253.3 0.2 1.4e-25 89.2 0.0 3.8 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 PVD31493.1 - 4.7e-16 58.4 0.1 4.7e-16 58.4 0.1 3.2 4 0 0 4 4 4 1 Homeodomain Homeobox_KN PF05920.11 PVD31493.1 - 0.00014 21.7 0.3 0.00064 19.6 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_ISL3 PF13542.6 PVD31493.1 - 0.15 11.5 0.0 0.96 8.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SBDS_C PF09377.10 PVD31493.1 - 0.26 11.3 2.3 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 SBDS protein C-terminal domain HTH_ABP1_N PF18107.1 PVD31493.1 - 0.41 10.4 0.0 0.41 10.4 0.0 4.8 6 0 0 6 6 6 0 Fission yeast centromere protein N-terminal domain CASP_C PF08172.12 PVD31494.1 - 3e-55 187.3 7.8 2.6e-54 184.2 7.8 2.0 1 1 0 1 1 1 1 CASP C terminal DUF2205 PF10224.9 PVD31494.1 - 0.00058 19.8 3.4 0.00058 19.8 3.4 1.7 2 0 0 2 2 2 1 Short coiled-coil protein Golgin_A5 PF09787.9 PVD31494.1 - 0.0014 18.1 0.7 0.0014 18.1 0.7 2.9 2 1 1 3 3 3 1 Golgin subfamily A member 5 NDUF_B8 PF05821.11 PVD31494.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) IFT57 PF10498.9 PVD31494.1 - 0.018 14.0 4.1 0.02 13.9 1.3 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.8 PVD31494.1 - 0.19 11.8 7.3 0.98 9.5 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 PVD31494.1 - 0.32 10.9 5.7 0.078 12.9 2.2 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CtIP_N PF10482.9 PVD31494.1 - 0.32 11.0 8.1 0.11 12.6 2.8 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Nodulin_late PF07127.11 PVD31494.1 - 0.32 11.3 1.3 0.5 10.7 1.3 1.2 1 0 0 1 1 1 0 Late nodulin protein APG6_N PF17675.1 PVD31494.1 - 0.43 11.1 8.1 1.2 9.6 2.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 PVD31494.1 - 0.77 10.4 6.7 2.1 9.0 1.4 2.7 2 1 0 2 2 2 0 SlyX DUF4200 PF13863.6 PVD31494.1 - 0.94 9.9 8.5 0.16 12.4 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ZapB PF06005.12 PVD31494.1 - 1.8 9.1 8.6 1.3 9.5 1.1 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 PVD31494.1 - 5 7.0 10.4 0.83 9.5 2.1 2.5 2 1 0 2 2 2 0 Septum formation initiator L_HMGIC_fpl PF10242.9 PVD31497.1 - 2.1e-11 44.3 0.2 3.5e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PAN_1 PF00024.26 PVD31498.1 - 2.3e-09 37.1 10.9 5.2e-06 26.3 1.0 3.3 2 1 1 3 3 3 2 PAN domain PAN_4 PF14295.6 PVD31498.1 - 2.4e-06 27.4 6.5 0.0095 15.8 0.4 2.9 2 0 0 2 2 2 2 PAN domain EB PF01683.18 PVD31498.1 - 0.69 10.3 13.8 0.032 14.5 4.0 3.2 3 0 0 3 3 3 0 EB module Ras PF00071.22 PVD31502.1 - 1.6e-24 86.3 0.1 6.8e-24 84.3 0.1 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD31502.1 - 9.2e-12 45.2 0.0 2.6e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31502.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF4265 PF14085.6 PVD31502.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) DUF4429 PF14472.6 PVD31503.1 - 0.015 15.8 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) Lipocalin PF00061.23 PVD31503.1 - 0.02 15.1 2.0 0.033 14.4 2.0 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Ras PF00071.22 PVD31504.1 - 1.5e-37 128.7 0.0 2.8e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31504.1 - 5e-19 68.7 0.0 1.2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Sulfotransfer_3 PF13469.6 PVD31504.1 - 4.2e-12 46.9 0.0 3.9e-10 40.5 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD31504.1 - 1.3e-10 41.3 0.1 3.2e-10 39.9 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Arf PF00025.21 PVD31504.1 - 5e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD31504.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 PVD31504.1 - 0.11 12.8 0.1 0.31 11.3 0.1 1.8 1 0 0 1 1 1 0 Mid domain of argonaute Tcp10_C PF07202.13 PVD31505.1 - 1.9e-84 282.0 7.9 2.9e-84 281.4 5.4 2.4 1 1 1 2 2 2 2 T-complex protein 10 C-terminus TSC22 PF01166.18 PVD31505.1 - 0.0028 17.9 18.9 0.4 11.0 1.4 3.8 3 0 0 3 3 3 3 TSC-22/dip/bun family Shugoshin_N PF07558.11 PVD31505.1 - 0.005 16.7 6.9 0.27 11.1 1.6 2.6 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 PVD31505.1 - 0.039 14.2 24.9 0.63 10.2 17.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 PVD31505.1 - 0.5 9.7 15.7 0.63 9.3 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 PVD31505.1 - 0.86 8.4 27.8 8.1 5.2 17.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PVD31505.1 - 1.5 8.8 25.0 15 5.7 24.0 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 PVD31505.1 - 2 8.9 33.3 18 5.9 18.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region CtIP_N PF10482.9 PVD31505.1 - 2.7 8.1 19.3 2.8 8.0 17.6 1.9 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Lebercilin PF15619.6 PVD31505.1 - 3.6 7.2 31.1 2.2e+03 -1.9 30.8 2.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WD40_alt PF14077.6 PVD31505.1 - 5.1 7.0 9.2 42 4.1 1.4 3.7 3 1 0 3 3 3 0 Alternative WD40 repeat motif DUF4527 PF15030.6 PVD31505.1 - 5.6 6.3 10.3 0.16 11.3 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4527) DivIC PF04977.15 PVD31505.1 - 8.2 6.3 21.9 0.82 9.5 1.0 4.2 2 1 2 4 4 4 0 Septum formation initiator Carb_anhydrase PF00194.21 PVD31507.1 - 5.5e-87 291.5 0.0 6.7e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CUB PF00431.20 PVD31508.1 - 2.3e-97 320.9 6.0 5.5e-18 65.3 0.0 6.2 5 1 1 6 6 6 6 CUB domain Fer4_17 PF13534.6 PVD31508.1 - 0.0046 17.5 5.5 2.5 8.7 0.2 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Adeno_E3_CR2 PF02439.15 PVD31508.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SBP PF03110.14 PVD31508.1 - 0.093 13.0 0.4 59 4.1 0.0 3.4 3 0 0 3 3 3 0 SBP domain TMEM154 PF15102.6 PVD31508.1 - 0.18 11.7 0.0 0.18 11.7 0.0 3.7 4 1 0 5 5 5 0 TMEM154 protein family MTHFR_C PF12225.8 PVD31508.1 - 0.23 11.1 3.1 43 3.9 0.1 3.9 3 0 0 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal Fer4_8 PF13183.6 PVD31508.1 - 2.5 8.6 5.6 32 5.0 0.1 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain C2 PF00168.30 PVD31509.1 - 4.1e-25 88.1 0.1 1.4e-15 57.5 0.0 4.4 3 1 0 3 3 3 2 C2 domain Membr_traf_MHD PF10540.9 PVD31509.1 - 0.044 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain GDPD PF03009.17 PVD31510.1 - 3e-20 73.1 0.1 3.6e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3437 PF11919.8 PVD31510.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Pkinase PF00069.25 PVD31511.1 - 1.7e-71 240.7 0.0 2.2e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31511.1 - 6.2e-33 114.2 0.0 8.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 PVD31511.1 - 3e-14 53.1 0.1 6.2e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 PVD31511.1 - 1.3e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD31511.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 PVD31511.1 - 0.0029 17.9 0.0 0.028 14.7 0.0 2.6 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 PVD31511.1 - 0.044 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PVD31511.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MAAL_N PF05034.13 PVD31511.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus APH PF01636.23 PVD31511.1 - 0.24 11.3 0.0 0.37 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.22 PVD31512.1 - 2.7e-82 277.0 0.0 3.2e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.21 PVD31513.1 - 2.9e-15 56.3 16.4 3.9e-15 55.9 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD31513.1 - 1.5e-13 50.7 13.6 2.2e-13 50.2 13.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD31513.1 - 3.3e-07 30.2 13.8 5.6e-07 29.5 13.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5337 PF17272.2 PVD31513.1 - 0.014 15.3 1.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF805 PF05656.14 PVD31513.1 - 3.9 7.9 9.6 2.3 8.7 1.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Glyco_hydro_2_C PF02836.17 PVD31514.1 - 9.3e-85 284.4 0.1 1.2e-84 284.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 PVD31514.1 - 1.2e-25 90.3 2.2 1.1e-24 87.2 0.8 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 PVD31514.1 - 3.6e-06 27.6 0.1 6.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 PVD31514.1 - 0.0041 17.7 0.8 0.013 16.0 0.5 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_2_C PF02836.17 PVD31515.1 - 1.1e-81 274.3 0.1 1.5e-81 273.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 PVD31515.1 - 7.8e-24 84.5 0.4 2e-23 83.1 0.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 PVD31515.1 - 5.8e-05 23.7 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 PVD31515.1 - 0.012 16.2 0.4 0.037 14.6 0.4 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Cellulase PF00150.18 PVD31515.1 - 0.042 13.3 0.4 0.3 10.5 0.4 2.2 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 PVD31516.1 - 3.3e-89 299.0 0.1 4.8e-83 278.7 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 PVD31516.1 - 6.1e-29 101.1 0.6 2.1e-23 83.1 0.4 3.5 4 0 0 4 4 4 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 PVD31516.1 - 2.9e-09 37.6 0.1 0.00011 22.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 PVD31516.1 - 0.018 15.6 1.8 0.054 14.1 0.4 2.6 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain FGGY_N PF00370.21 PVD31517.1 - 2.9e-29 102.3 1.0 2e-28 99.6 1.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 PVD31517.1 - 0.013 15.0 0.1 0.021 14.3 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family VWA_3 PF13768.6 PVD31517.1 - 0.029 14.3 0.0 0.09 12.7 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain ROK PF00480.20 PVD31517.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 ROK family FlgD_ig PF13860.6 PVD31517.1 - 0.12 12.3 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain DUF3099 PF11298.8 PVD31518.1 - 0.07 13.3 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) TMPIT PF07851.13 PVD31519.1 - 1.6e-139 464.7 16.1 1.9e-139 464.4 16.1 1.0 1 0 0 1 1 1 1 TMPIT-like protein eIF3_subunit PF08597.10 PVD31519.1 - 0.0013 18.7 0.3 0.0023 17.9 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF19 PF01579.18 PVD31519.1 - 0.0038 17.0 4.0 0.0077 16.0 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF19) LTXXQ PF07813.12 PVD31519.1 - 0.033 14.9 2.9 0.047 14.4 2.0 1.8 1 1 0 1 1 1 0 LTXXQ motif family protein DUF2193 PF09959.9 PVD31519.1 - 0.055 11.9 0.2 0.084 11.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) EII-Sor PF03609.14 PVD31519.1 - 0.23 10.8 0.1 0.23 10.8 0.1 2.5 2 1 0 2 2 2 0 PTS system sorbose-specific iic component DUF948 PF06103.11 PVD31519.1 - 0.25 11.6 1.0 1 9.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMEM107 PF14995.6 PVD31519.1 - 1.1 9.7 8.0 0.29 11.6 1.7 2.4 2 0 0 2 2 2 0 Transmembrane protein DUF1043 PF06295.12 PVD31519.1 - 1.8 8.6 5.7 4 7.5 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3128 PF11326.8 PVD31519.1 - 5 7.6 6.1 63 4.0 6.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DAO PF01266.24 PVD31520.1 - 1.6e-51 176.0 0.0 1.8e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PVD31520.1 - 2.5e-05 23.7 0.0 0.00053 19.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD31520.1 - 9.6e-05 21.7 0.0 0.0029 16.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PVD31520.1 - 0.00012 21.3 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PVD31520.1 - 0.00032 19.9 0.0 0.00073 18.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PVD31520.1 - 0.0014 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PVD31520.1 - 0.0033 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 PVD31520.1 - 0.0038 16.0 0.0 0.064 12.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 PVD31520.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PVD31520.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 PVD31520.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 PVD31521.1 - 3.3e-71 239.7 0.0 5.2e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31521.1 - 3.2e-35 121.7 0.0 4.5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PVD31521.1 - 2.4e-10 40.9 4.3 2.4e-10 40.9 4.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 PVD31521.1 - 5.9e-06 25.8 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PVD31521.1 - 0.00039 20.1 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PVD31521.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PVD31521.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PVD31521.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PVD31521.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 PVD31522.1 - 1.1e-68 231.5 0.0 1.5e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31522.1 - 3.8e-34 118.1 0.0 5.4e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PVD31522.1 - 1.1e-10 42.0 8.0 1.8e-10 41.3 5.6 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 PVD31522.1 - 3.1e-05 23.5 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD31522.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PVD31522.1 - 0.018 14.7 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PVD31522.1 - 0.03 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PVD31522.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PVD31522.1 - 0.13 11.3 0.0 0.62 9.1 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 HEAT PF02985.22 PVD31523.1 - 1.3e-46 152.5 34.8 0.00049 20.1 0.0 23.8 25 0 0 25 25 23 7 HEAT repeat HEAT_EZ PF13513.6 PVD31523.1 - 2.7e-37 126.7 47.9 0.00017 22.0 0.1 21.6 19 4 3 23 23 23 10 HEAT-like repeat HEAT_2 PF13646.6 PVD31523.1 - 1.8e-32 111.5 25.7 0.0002 21.7 0.0 14.8 10 5 8 18 18 17 8 HEAT repeats Adaptin_N PF01602.20 PVD31523.1 - 2.1e-21 76.1 1.0 7.8e-06 24.7 0.0 8.3 5 2 0 6 6 6 4 Adaptin N terminal region Cnd1 PF12717.7 PVD31523.1 - 2.4e-21 76.4 1.4 0.07 13.2 0.0 10.6 7 2 4 12 12 12 6 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 PVD31523.1 - 1.4e-16 60.8 0.5 0.00029 20.5 0.0 9.4 10 1 1 11 11 11 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 PVD31523.1 - 1.6e-10 41.4 0.0 0.7 10.5 0.0 9.3 10 2 2 12 12 11 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 PVD31523.1 - 4.4e-10 40.0 7.7 0.53 10.4 0.1 8.7 8 2 1 9 9 9 2 Parkin co-regulated protein Gcn1_N PF12074.8 PVD31523.1 - 2.1e-09 37.2 5.9 8.6e-07 28.6 1.1 4.9 5 1 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal UME PF08064.13 PVD31523.1 - 6.3e-09 35.7 12.0 0.03 14.2 0.0 10.4 12 1 0 12 12 12 2 UME (NUC010) domain DUF937 PF06078.11 PVD31523.1 - 8.9e-07 29.6 2.0 8.9 6.9 0.0 6.4 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF937) TAF6_C PF07571.13 PVD31523.1 - 1.3e-05 25.4 1.6 30 5.0 0.0 8.1 7 2 1 8 8 7 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 PVD31523.1 - 0.00049 20.0 19.0 18 5.5 0.2 9.8 9 1 0 9 9 8 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 PVD31523.1 - 0.00052 19.3 27.0 0.3 10.2 0.1 10.0 8 3 4 12 12 12 1 RNAPII transcription regulator C-terminal TIP120 PF08623.10 PVD31523.1 - 0.00089 19.1 0.4 2.5 7.9 0.0 5.4 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 PVD31523.1 - 0.001 19.0 3.2 1.3 8.9 0.0 5.9 7 1 0 7 7 5 1 Domain of unknown function (DUF3385) DUF4611 PF15387.6 PVD31523.1 - 0.046 13.9 0.2 1.8 8.8 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Tti2 PF10521.9 PVD31523.1 - 0.18 11.3 6.9 11 5.4 0.0 5.8 6 0 0 6 6 6 0 Tti2 family RTP1_C1 PF10363.9 PVD31523.1 - 0.36 11.0 8.4 2.6e+02 1.8 0.0 8.2 8 2 1 9 9 9 0 Required for nuclear transport of RNA pol II C-terminus 1 EF-hand_4 PF12763.7 PVD31524.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Cadherin_tail PF15974.5 PVD31524.1 - 0.11 12.8 2.2 0.59 10.5 2.2 2.3 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Pkinase PF00069.25 PVD31525.1 - 7.1e-70 235.4 0.0 1.5e-69 234.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31525.1 - 3.9e-31 108.3 0.0 3.9e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD31525.1 - 0.0014 17.6 0.2 0.0028 16.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PVD31525.1 - 0.01 15.2 0.2 0.025 13.9 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD31525.1 - 0.29 11.0 4.3 1.2 9.0 0.2 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family Tubulin PF00091.25 PVD31526.1 - 1.3e-49 169.1 0.0 1.8e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 PVD31526.1 - 0.15 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like ATP_bind_1 PF03029.17 PVD31529.1 - 2e-79 266.8 0.5 2.7e-79 266.4 0.0 1.4 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 PVD31529.1 - 3.6e-05 23.8 0.0 0.00016 21.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD31529.1 - 4.1e-05 24.0 0.2 0.00029 21.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 PVD31529.1 - 5.9e-05 22.7 1.4 0.23 11.0 1.2 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PVD31529.1 - 0.0002 21.7 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PVD31529.1 - 0.00038 20.6 0.3 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 PVD31529.1 - 0.00072 19.0 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit NACHT PF05729.12 PVD31529.1 - 0.00086 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 PVD31529.1 - 0.0017 17.9 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 PVD31529.1 - 0.0018 17.8 0.0 0.049 13.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD31529.1 - 0.0019 18.1 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase SRP54 PF00448.22 PVD31529.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 PVD31529.1 - 0.0027 18.3 0.2 0.017 15.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain G-alpha PF00503.20 PVD31529.1 - 0.0042 16.3 0.4 0.044 12.9 0.0 2.3 2 1 0 2 2 2 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 PVD31529.1 - 0.0043 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 PVD31529.1 - 0.0052 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 PVD31529.1 - 0.0079 15.5 0.5 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 PVD31529.1 - 0.0088 15.6 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 PVD31529.1 - 0.011 16.1 0.1 0.029 14.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain CLP1_P PF16575.5 PVD31529.1 - 0.011 15.5 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 PVD31529.1 - 0.014 15.5 0.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 PVD31529.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PVD31529.1 - 0.02 14.9 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PVD31529.1 - 0.021 14.6 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 PVD31529.1 - 0.021 13.8 0.2 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 PVD31529.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 PVD31529.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 PVD31529.1 - 0.038 14.2 0.0 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UvrD-helicase PF00580.21 PVD31529.1 - 0.039 13.5 0.9 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_28 PF13521.6 PVD31529.1 - 0.039 14.2 0.4 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 PVD31529.1 - 0.039 13.6 0.3 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 PVD31529.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 PVD31529.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 PVD31529.1 - 0.063 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 PVD31529.1 - 0.075 13.4 0.0 0.96 9.9 0.0 2.6 2 1 0 2 2 2 0 RNA helicase Ras PF00071.22 PVD31529.1 - 0.099 12.2 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 PVD31529.1 - 0.1 12.3 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 PVD31529.1 - 0.11 11.8 1.2 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_7 PF12775.7 PVD31529.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region dNK PF01712.19 PVD31529.1 - 0.12 12.2 1.9 0.49 10.2 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase ATPase_2 PF01637.18 PVD31529.1 - 0.15 12.0 1.5 0.71 9.7 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 PVD31529.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Dynamin_N PF00350.23 PVD31529.1 - 0.16 12.0 5.6 19 5.3 0.0 3.9 3 1 1 4 4 3 0 Dynamin family AAA_14 PF13173.6 PVD31529.1 - 0.18 11.8 1.6 0.57 10.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain FKBP_N PF01346.18 PVD31529.1 - 0.35 11.9 4.1 0.28 12.1 0.7 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase U1snRNP70_N PF12220.8 PVD31529.1 - 1.1 10.0 11.2 0.13 12.9 4.8 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UBN_AB PF14075.6 PVD31529.1 - 1.2 8.8 6.8 1.5 8.5 1.9 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain LPD5 PF18799.1 PVD31529.1 - 2.6 8.5 10.8 0.33 11.4 5.6 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 SlyX PF04102.12 PVD31530.1 - 2 9.1 17.9 2.1 9.0 6.3 4.2 2 1 2 4 4 4 0 SlyX EMP24_GP25L PF01105.24 PVD31530.1 - 9.6 6.1 13.4 11 5.9 2.9 2.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Cob_adeno_trans PF01923.18 PVD31531.1 - 1.3e-56 191.3 0.0 1.5e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Flagellar_rod PF05149.12 PVD31531.1 - 0.027 13.9 0.7 0.054 13.0 0.7 1.5 1 0 0 1 1 1 0 Paraflagellar rod protein CSN5_C PF18323.1 PVD31531.1 - 0.1 13.5 0.0 0.16 12.9 0.0 1.5 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Pox_A_type_inc PF04508.12 PVD31531.1 - 9 6.3 6.6 0.7 9.8 0.1 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat BTB_2 PF02214.22 PVD31533.1 - 4.1e-15 55.9 0.0 6.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_1 PF00685.27 PVD31534.1 - 4.2e-44 151.0 5.4 3.5e-32 112.0 2.4 3.1 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31534.1 - 3.8e-11 43.8 0.7 3.2e-06 27.7 0.2 3.1 2 1 1 3 3 3 2 Sulfotransferase family DUF2544 PF11245.8 PVD31534.1 - 0.0014 18.1 0.1 0.96 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2544) DUF4849 PF16141.5 PVD31534.1 - 0.01 15.1 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 FGE-sulfatase PF03781.16 PVD31534.1 - 0.018 14.6 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Sulfatase-modifying factor enzyme 1 IKKbetaNEMObind PF12179.8 PVD31534.1 - 0.021 14.9 0.1 19 5.4 0.0 3.3 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain LupA PF18242.1 PVD31534.1 - 0.032 13.9 0.0 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Legionella ubiquitin-specific protease A domain Glyc_hyd_38C_2 PF18230.1 PVD31534.1 - 0.075 13.2 0.4 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal sub-domain SF3A3 PF16837.5 PVD31534.1 - 0.099 13.2 0.6 6.6 7.3 0.2 2.8 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 BRK PF07533.16 PVD31534.1 - 0.18 11.4 0.4 30 4.3 0.1 2.8 2 0 0 2 2 2 0 BRK domain SIR2 PF02146.17 PVD31535.1 - 1.8e-51 174.6 0.0 2.6e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Nudix_N_2 PF14803.6 PVD31535.1 - 0.078 12.9 0.6 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Nudix N-terminal WD40 PF00400.32 PVD31536.1 - 1.6e-11 44.6 5.4 5.1e-06 27.1 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 PVD31536.1 - 0.017 13.9 0.0 0.87 8.3 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Ribosomal_L50 PF10501.9 PVD31537.1 - 7.4e-13 48.6 0.9 8.3e-13 48.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal subunit 39S BCAS2 PF05700.11 PVD31538.1 - 6.7e-56 189.2 10.4 6.4e-51 173.0 5.4 2.0 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) EzrA PF06160.12 PVD31538.1 - 0.0034 15.6 3.9 0.005 15.1 3.6 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 PVD31538.1 - 0.0038 16.7 6.0 0.0038 16.7 6.0 1.3 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF3450 PF11932.8 PVD31538.1 - 0.0053 16.1 4.3 0.007 15.7 3.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) TACC_C PF05010.14 PVD31538.1 - 0.027 14.3 6.8 0.059 13.2 5.4 1.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 PVD31538.1 - 0.029 14.2 2.6 0.041 13.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 PVD31538.1 - 0.066 12.5 0.9 0.09 12.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 PVD31538.1 - 0.07 13.5 4.2 0.1 12.9 0.3 2.4 3 0 0 3 3 2 0 Csm1 N-terminal domain Mt_ATP-synt_B PF05405.14 PVD31538.1 - 0.077 12.6 3.4 0.12 12.0 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sirohm_synth_C PF14823.6 PVD31538.1 - 0.11 12.1 2.0 0.24 11.1 2.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal PRKG1_interact PF15898.5 PVD31538.1 - 0.25 12.3 8.9 0.38 11.7 7.5 1.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMCO5 PF14992.6 PVD31538.1 - 0.4 10.2 6.9 0.45 10.1 6.0 1.5 1 1 0 1 1 1 0 TMCO5 family FlaC_arch PF05377.11 PVD31538.1 - 0.74 10.3 4.1 2.2 8.7 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YdjC PF04794.12 PVD31539.1 - 7.2e-57 193.0 0.0 8.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein GLE1 PF07817.13 PVD31540.1 - 2.8e-75 252.8 0.0 2.8e-75 252.8 0.0 2.5 2 1 0 2 2 2 1 GLE1-like protein Vac_Fusion PF02346.16 PVD31540.1 - 0.13 11.9 3.8 4.6 6.9 2.2 3.5 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Piwi PF02171.17 PVD31541.1 - 5.1e-88 295.2 1.1 5.7e-88 295.1 0.1 1.6 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 PVD31541.1 - 1.5e-34 118.7 0.5 3.8e-34 117.4 0.5 1.6 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 PVD31541.1 - 1.9e-06 28.5 0.0 7.4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 PVD31541.1 - 0.0015 18.8 0.1 0.041 14.2 0.0 3.1 3 0 0 3 3 3 1 Argonaute linker 2 domain WD40 PF00400.32 PVD31542.1 - 5.1e-09 36.6 5.0 0.022 15.6 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD31542.1 - 4.6e-05 23.6 0.4 0.76 10.1 0.1 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Phospholip_B PF04916.13 PVD31543.1 - 1.3e-120 403.5 4.9 2.6e-113 379.4 2.3 2.0 1 1 1 2 2 2 2 Phospholipase B Phage_gp53 PF11246.8 PVD31543.1 - 0.028 14.1 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 Base plate wedge protein 53 zf-H2C2_5 PF13909.6 PVD31544.1 - 1.5e-21 75.8 29.5 4e-08 32.9 0.6 5.3 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD31544.1 - 2.1e-12 46.9 54.5 0.00052 20.3 0.3 9.4 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2 PF00096.26 PVD31544.1 - 1.2e-09 38.1 66.0 0.0012 19.2 1.5 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD31544.1 - 2.6e-09 37.1 59.8 0.097 13.6 0.4 9.6 9 0 0 9 9 9 6 C2H2-type zinc finger Sushi PF00084.20 PVD31546.1 - 0.00041 20.9 1.4 0.00081 19.9 1.4 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) PAXIP1_C PF15364.6 PVD31547.1 - 1.4e-23 83.7 3.4 1.9e-23 83.2 3.4 1.2 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4684 PF15736.5 PVD31547.1 - 0.027 13.1 4.7 0.044 12.5 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Pkinase PF00069.25 PVD31548.1 - 3.5e-64 216.7 0.0 4.7e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31548.1 - 3.4e-32 111.8 0.0 5.7e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD31548.1 - 0.00046 19.3 0.2 0.00068 18.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD31548.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD31548.1 - 0.0021 17.5 0.0 0.0049 16.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD31548.1 - 0.019 14.4 0.3 0.032 13.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDUF_B4 PF07225.12 PVD31548.1 - 0.031 14.2 0.1 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Choline_kinase PF01633.20 PVD31548.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Thioredoxin_4 PF13462.6 PVD31549.1 - 0.0071 16.5 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin C-C_Bond_Lyase PF15617.6 PVD31549.1 - 0.054 12.6 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Auts2 PF15336.6 PVD31550.1 - 8e-27 94.8 13.0 8e-27 94.8 13.0 5.5 5 2 1 6 6 6 2 Autism susceptibility gene 2 protein RR_TM4-6 PF06459.12 PVD31553.1 - 0.018 14.9 1.8 0.019 14.8 1.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Transglut_core2 PF13369.6 PVD31554.1 - 2.8e-33 114.7 0.0 5.2e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 PVD31554.1 - 9.7e-26 90.1 1.2 3.7e-25 88.3 0.5 2.3 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Mre11_DNA_bind PF04152.14 PVD31554.1 - 0.16 12.3 1.1 0.32 11.3 1.1 1.4 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DnaJ PF00226.31 PVD31555.1 - 4e-16 58.9 0.0 9.4e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 PVD31555.1 - 1.2e-11 44.5 2.1 1.5e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin zf-CSL PF05207.13 PVD31555.1 - 2.9e-10 39.7 11.7 6.6e-10 38.6 11.7 1.7 1 0 0 1 1 1 1 CSL zinc finger zf-TRAF PF02176.18 PVD31556.1 - 3.3e-38 130.2 37.2 9.4e-16 58.3 8.3 4.5 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C2HC_2 PF13913.6 PVD31556.1 - 0.034 14.1 0.2 0.034 14.1 0.2 3.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-TRAF_2 PF15965.5 PVD31556.1 - 0.1 13.1 36.5 0.4 11.2 4.0 5.1 2 1 4 6 6 6 0 TRAF-like zinc-finger DUF2318 PF10080.9 PVD31556.1 - 0.5 10.5 10.5 0.77 9.9 0.7 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-CHCC PF10276.9 PVD31556.1 - 2.7 8.1 7.8 0.28 11.3 0.9 2.8 2 0 0 2 2 2 0 Zinc-finger domain Acyl-CoA_dh_1 PF00441.24 PVD31558.1 - 2.4e-39 134.9 2.3 2.6e-39 134.8 2.3 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD31558.1 - 7.8e-19 68.3 0.2 8.9e-19 68.1 0.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.22 PVD31559.1 - 1.1e-14 53.9 0.1 1.4e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain Med13_C PF06333.12 PVD31560.1 - 4.4e-101 338.4 0.1 4.4e-101 338.4 0.1 3.9 5 0 0 5 5 5 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 PVD31560.1 - 1.1e-63 215.3 0.0 2.3e-63 214.3 0.0 1.6 1 0 0 1 1 1 1 MID domain of medPIWI Med13_N PF11597.8 PVD31560.1 - 3.8e-26 92.2 0.2 9.6e-26 90.9 0.2 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Apt1 PF10351.9 PVD31561.1 - 1.5e-96 324.1 23.3 2.1e-67 228.1 13.7 2.8 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 PVD31561.1 - 1.7e-28 99.7 0.0 6.2e-28 97.9 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 PVD31561.1 - 6.6e-10 39.1 0.5 3.1e-09 36.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) T6PP_N PF18572.1 PVD31561.1 - 0.011 15.5 1.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-M PF11111.8 PVD31562.1 - 2e-45 154.1 0.0 5.4e-45 152.7 0.0 1.8 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Sin3_corepress PF08295.12 PVD31562.1 - 0.44 10.7 8.0 0.43 10.7 0.4 3.8 2 0 0 2 2 2 0 Sin3 family co-repressor HSBP1 PF06825.12 PVD31562.1 - 0.97 9.3 18.5 0.014 15.3 3.3 4.5 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Carb_anhydrase PF00194.21 PVD31563.1 - 6.4e-108 360.1 3.4 1.7e-36 126.0 0.3 3.1 2 1 1 3 3 3 3 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD31564.1 - 7.2e-17 61.8 0.2 8.7e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD31565.1 - 3.3e-67 226.7 0.4 6.1e-67 225.8 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD31566.1 - 2.7e-65 220.4 0.0 3.1e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD31567.1 - 3e-95 318.6 0.1 3.4e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CBM_14 PF01607.24 PVD31570.1 - 2.1e-07 31.0 16.1 9.5e-05 22.5 4.7 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Fez1 PF06818.15 PVD31571.1 - 0.0098 16.4 27.4 0.0098 16.4 27.4 9.7 1 1 9 10 10 10 3 Fez1 NiFe-hyd_HybE PF11939.8 PVD31571.1 - 1.1 9.2 7.4 0.51 10.2 2.4 3.3 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE Med15 PF09606.10 PVD31572.1 - 3.5e-106 356.8 48.6 2.8e-85 287.6 41.7 2.0 1 1 1 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal KIX PF02172.16 PVD31572.1 - 0.0021 18.3 0.2 0.012 15.9 0.1 2.2 2 0 0 2 2 2 1 KIX domain KIX_2 PF16987.5 PVD31572.1 - 0.036 14.1 0.2 0.21 11.6 0.1 2.5 2 1 0 2 2 2 0 KIX domain E1-E2_ATPase PF00122.20 PVD31575.1 - 8.8e-56 188.3 0.5 8.8e-56 188.3 0.5 4.1 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PVD31575.1 - 8.8e-45 152.6 5.3 8.8e-45 152.6 5.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PVD31575.1 - 2e-21 77.2 0.0 1.3e-20 74.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PVD31575.1 - 1.1e-20 73.4 0.0 2.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PVD31575.1 - 4.2e-13 48.8 0.1 1.3e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 PVD31575.1 - 7.4e-08 33.0 0.0 5.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PVD31575.1 - 1.7e-06 28.0 1.0 0.00012 21.9 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SPC12 PF06645.13 PVD31575.1 - 0.048 13.8 1.9 0.16 12.1 0.1 2.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GHL6 PF14871.6 PVD31575.1 - 0.065 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 LAL_C2 PF18603.1 PVD31575.1 - 2.4 8.4 4.6 1.6 9.0 0.1 2.8 3 1 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Med15 PF09606.10 PVD31576.1 - 1.3e-07 30.8 0.2 1.8e-07 30.3 0.1 1.3 1 1 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Sperm_Ag_HE2 PF05324.13 PVD31577.1 - 0.086 13.3 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Sperm antigen HE2 7tm_1 PF00001.21 PVD31578.1 - 5.4e-06 25.9 3.2 2.5e-05 23.8 3.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Chitin_synth_2 PF03142.15 PVD31579.1 - 2.3e-21 76.0 12.1 5.7e-19 68.1 5.8 3.0 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD31579.1 - 2.1e-14 53.9 7.0 2.1e-14 53.9 7.0 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD31579.1 - 0.00039 20.4 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PVD31579.1 - 0.00094 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sulfotransfer_2 PF03567.14 PVD31581.1 - 2.1e-25 90.1 3.7 2.8e-22 79.8 0.0 2.8 3 0 0 3 3 3 2 Sulfotransferase family Mucin PF01456.17 PVD31581.1 - 0.015 15.3 7.1 0.028 14.4 7.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 PVD31581.1 - 0.86 9.6 7.8 2 8.4 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4871 PF16167.5 PVD31581.1 - 2.5 8.1 5.2 1.3e+02 2.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4871) UNC-93 PF05978.16 PVD31583.1 - 4.6e-10 39.4 12.6 4.6e-10 39.4 12.6 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 PVD31583.1 - 1.2e-06 27.8 3.0 1.2e-06 27.8 3.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MAPEG PF01124.18 PVD31584.1 - 2.3e-15 56.6 1.8 3.1e-15 56.2 1.8 1.1 1 0 0 1 1 1 1 MAPEG family Guanylate_kin PF00625.21 PVD31585.1 - 1.5e-37 129.1 0.1 3.8e-33 114.7 0.0 2.3 1 1 1 2 2 2 2 Guanylate kinase L27 PF02828.16 PVD31585.1 - 3.5e-12 45.9 0.0 7.7e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 L27 domain PDZ PF00595.24 PVD31585.1 - 4.9e-10 39.6 0.3 9.8e-10 38.7 0.3 1.5 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 PVD31585.1 - 6.4e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD31585.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 PVD31585.1 - 3.4e-06 26.8 0.0 9.5e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain RsgA_GTPase PF03193.16 PVD31585.1 - 1.3e-05 25.2 0.0 3.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase PDZ_2 PF13180.6 PVD31585.1 - 6.7e-05 23.1 0.1 0.00018 21.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 PVD31585.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.23 PVD31585.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 PVD31585.1 - 0.12 11.8 0.1 9.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 PVD31585.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 PVD31585.1 - 0.19 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.24 PVD31586.1 - 1.1e-36 126.5 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Innexin PF00876.18 PVD31586.1 - 0.046 13.0 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Innexin SdrD_B PF17210.3 PVD31586.1 - 0.071 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 SdrD B-like domain Jnk-SapK_ap_N PF09744.9 PVD31587.1 - 2.1e-33 115.7 19.9 2.1e-33 115.7 19.9 3.0 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 PVD31587.1 - 4.3e-15 55.7 1.9 4.3e-15 55.7 1.9 3.9 3 1 0 3 3 3 1 Rab interacting lysosomal protein ADIP PF11559.8 PVD31587.1 - 0.0093 16.1 14.4 0.0093 16.1 14.4 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Filament PF00038.21 PVD31587.1 - 0.86 9.1 44.7 0.029 14.0 8.3 3.2 1 1 2 3 3 3 0 Intermediate filament protein GIT_CC PF16559.5 PVD31587.1 - 1 9.3 13.3 0.54 10.2 2.5 3.6 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 PVD31587.1 - 6 7.0 27.9 0.13 12.3 1.8 4.7 2 1 2 4 4 4 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 PVD31588.1 - 3.1e-32 112.0 18.4 3.1e-32 112.0 18.4 3.0 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 PVD31588.1 - 3.3e-11 43.2 2.3 3.3e-11 43.2 2.3 3.8 3 1 0 3 3 3 2 Rab interacting lysosomal protein Bap31_Bap29_C PF18035.1 PVD31588.1 - 0.00023 21.1 0.6 0.028 14.4 0.8 4.9 5 1 0 5 5 5 2 Bap31/Bap29 cytoplasmic coiled-coil domain Golgin_A5 PF09787.9 PVD31588.1 - 0.65 9.4 40.7 0.53 9.7 36.5 2.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 PKcGMP_CC PF16808.5 PVD31588.1 - 0.83 9.6 9.8 2.2 8.2 0.7 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PRKG1_interact PF15898.5 PVD31588.1 - 9.5 7.2 40.4 0.085 13.8 7.6 4.3 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain AAA_34 PF13872.6 PVD31589.1 - 8.9e-144 478.0 0.0 1.3e-143 477.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 PVD31589.1 - 2.5e-120 401.3 0.1 4.3e-120 400.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 PVD31589.1 - 1.8e-06 28.1 0.0 5.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SR-25 PF10500.9 PVD31589.1 - 0.0011 18.6 17.5 0.0011 18.6 17.5 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Helicase_C PF00271.31 PVD31589.1 - 0.021 15.2 0.0 0.078 13.3 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SET PF00856.28 PVD31590.1 - 6.1e-21 75.5 0.1 3.5e-20 73.1 0.1 2.2 1 1 0 1 1 1 1 SET domain Membralin PF09746.9 PVD31590.1 - 0.074 12.1 0.6 0.11 11.5 0.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein SAF PF08666.12 PVD31590.1 - 0.17 12.5 0.0 1.2 9.8 0.0 2.4 3 0 0 3 3 3 0 SAF domain Ndc1_Nup PF09531.10 PVD31590.1 - 0.21 10.2 2.2 0.26 9.9 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAP PF07174.11 PVD31591.1 - 0.079 12.4 17.9 0.09 12.2 17.9 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PPP4R2 PF09184.11 PVD31593.1 - 0.0031 17.2 11.6 0.0031 17.2 11.6 1.2 1 0 0 1 1 1 1 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 PVD31593.1 - 0.0052 17.1 15.0 0.0059 16.9 15.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 PVD31593.1 - 0.0062 15.9 16.7 0.007 15.7 16.7 1.1 1 0 0 1 1 1 1 NOA36 protein SDA1 PF05285.12 PVD31593.1 - 0.007 15.8 10.8 0.007 15.8 10.8 1.1 1 0 0 1 1 1 1 SDA1 Voldacs PF03517.13 PVD31593.1 - 0.011 15.8 6.3 0.016 15.4 6.3 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Dicty_REP PF05086.12 PVD31593.1 - 0.044 11.8 4.7 0.041 11.9 4.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RXT2_N PF08595.11 PVD31593.1 - 0.053 13.6 8.8 0.068 13.2 8.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2722 PF10846.8 PVD31593.1 - 0.054 12.4 4.8 0.057 12.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleo_P87 PF07267.11 PVD31593.1 - 0.077 11.8 4.5 0.07 12.0 4.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sporozoite_P67 PF05642.11 PVD31593.1 - 0.091 10.8 5.4 0.099 10.7 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 PVD31593.1 - 0.11 10.7 15.5 0.11 10.7 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 PVD31593.1 - 0.21 10.5 2.7 0.19 10.7 2.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SspB PF04386.13 PVD31593.1 - 0.28 11.1 7.2 0.41 10.5 7.2 1.2 1 0 0 1 1 1 0 Stringent starvation protein B TFB6 PF17110.5 PVD31593.1 - 0.68 9.7 6.0 0.75 9.5 6.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4746 PF15928.5 PVD31593.1 - 0.78 9.1 13.9 0.86 9.0 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 PVD31593.1 - 1.4 7.7 16.4 1.7 7.5 16.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Presenilin PF01080.17 PVD31593.1 - 2.2 6.9 4.6 2.1 7.0 3.8 1.5 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 PVD31593.1 - 2.7 6.2 18.0 3.4 5.9 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 PVD31593.1 - 5.4 6.3 8.0 6.9 6.0 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP1_TM PF14812.6 PVD31593.1 - 5.5 7.4 15.2 9 6.7 15.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 PVD31593.1 - 9 5.4 5.3 10 5.2 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sulfotransfer_1 PF00685.27 PVD31594.1 - 1.4e-31 109.9 0.0 4.6e-30 105.0 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31594.1 - 0.029 14.8 0.0 3.4 8.0 0.0 2.2 1 1 0 2 2 2 0 Sulfotransferase family Pro_isomerase PF00160.21 PVD31595.1 - 4.2e-52 176.6 0.0 7.5e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PVD31595.1 - 2.4e-09 37.0 10.5 5.1e-08 32.6 0.2 2.4 2 1 0 2 2 2 2 Rtf2 RING-finger zf-NOSIP PF15906.5 PVD31595.1 - 0.0018 18.4 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 PVD31595.1 - 0.031 14.1 0.0 0.17 11.8 0.0 2.2 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Cas6b_N PF17955.1 PVD31595.1 - 0.072 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Cas6b N-terminal domain DUF5121 PF17165.4 PVD31595.1 - 0.098 13.1 1.4 0.44 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5121) 7tm_1 PF00001.21 PVD31596.1 - 2.1e-22 79.7 6.6 2.5e-22 79.5 6.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD31596.1 - 3.4e-06 26.6 3.0 5.2e-06 26.0 3.0 1.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4271 PF14093.6 PVD31596.1 - 0.003 17.5 0.2 0.77 9.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4271) TMEM223 PF14640.6 PVD31596.1 - 0.37 10.9 2.8 0.56 10.4 0.7 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 Neur_chan_LBD PF02931.23 PVD31597.1 - 6.9e-42 143.3 2.0 1.1e-41 142.7 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD31597.1 - 3.2e-08 33.9 7.7 1.2e-06 28.8 5.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region SMAP PF15477.6 PVD31598.1 - 4.8e-15 56.3 0.7 4.8e-15 56.3 0.7 2.2 2 1 0 2 2 2 1 Small acidic protein family UPF0492 PF15744.5 PVD31598.1 - 0.0025 17.1 4.7 0.0031 16.8 4.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 DUF3460 PF11943.8 PVD31598.1 - 3.7 7.9 6.6 0.4 11.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Zip PF02535.22 PVD31599.1 - 0.13 11.5 2.4 0.14 11.3 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 PVD31599.1 - 0.18 10.0 20.5 0.22 9.7 20.5 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 PVD31599.1 - 0.29 9.9 6.6 0.36 9.5 6.6 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 PVD31599.1 - 0.29 9.6 11.6 0.34 9.4 11.6 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 PVD31599.1 - 0.6 9.7 27.3 0.89 9.1 27.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 PVD31599.1 - 1.2 7.9 13.2 1.5 7.6 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 PVD31599.1 - 2.7 6.0 9.2 3.3 5.7 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PVD31599.1 - 6.5 4.9 13.7 8.2 4.6 13.7 1.2 1 0 0 1 1 1 0 CDC45-like protein AMP-binding PF00501.28 PVD31600.1 - 1.7e-40 138.9 0.0 2.5e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 PVD31600.1 - 2.3e-09 37.0 4.2 4.3e-09 36.1 4.2 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 PVD31600.1 - 0.01 16.8 0.2 0.065 14.2 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain KASH_CCD PF14662.6 PVD31602.1 - 0.21 11.4 0.3 0.29 10.9 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH WD40 PF00400.32 PVD31603.1 - 2.4e-14 53.5 1.0 0.0014 19.4 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat CDP-OH_P_transf PF01066.21 PVD31604.1 - 3.4e-11 43.8 1.5 3.4e-11 43.8 1.5 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SSF PF00474.17 PVD31605.1 - 6.8e-113 377.6 25.1 1.6e-93 313.8 11.1 2.2 1 1 1 2 2 2 2 Sodium:solute symporter family DUF1129 PF06570.11 PVD31605.1 - 0.16 11.4 0.0 0.16 11.4 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 PVD31605.1 - 9.5 5.8 7.5 1.8 8.2 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Denso_VP4 PF02336.15 PVD31607.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Capsid protein VP4 Yippee-Mis18 PF03226.14 PVD31609.1 - 1.2e-12 48.0 0.6 1.4e-12 47.7 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 PVD31609.1 - 0.035 14.3 1.7 0.037 14.2 0.5 1.5 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling 7tm_1 PF00001.21 PVD31610.1 - 2.2e-21 76.4 0.0 4.3e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gp5_C PF06715.12 PVD31610.1 - 0.85 9.9 4.3 0.39 11.0 1.4 2.0 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) DUF2207 PF09972.9 PVD31610.1 - 1.4 7.6 3.3 3.1 6.5 1.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) GIDA PF01134.22 PVD31611.1 - 3.9e-119 398.2 0.0 2e-117 392.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Na_sulph_symp PF00939.19 PVD31611.1 - 6e-82 276.2 30.6 1.3e-49 169.5 14.4 2.1 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region GIDA_assoc PF13932.6 PVD31611.1 - 3.3e-54 184.3 0.1 5.4e-54 183.6 0.1 1.3 1 0 0 1 1 1 1 GidA associated domain CitMHS PF03600.16 PVD31611.1 - 2.3e-32 112.4 49.3 6.4e-16 58.4 12.2 2.8 2 1 1 3 3 3 3 Citrate transporter FAD_oxidored PF12831.7 PVD31611.1 - 4.9e-08 32.7 1.5 7.8e-08 32.1 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD31611.1 - 1.3e-07 31.1 5.3 0.0018 17.5 2.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PVD31611.1 - 0.00021 20.7 1.6 0.00057 19.2 1.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PVD31611.1 - 0.0016 17.8 0.2 0.0032 16.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF572 PF04502.13 PVD31611.1 - 0.0056 16.3 0.2 0.0084 15.8 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) RSN1_TM PF13967.6 PVD31611.1 - 0.0093 15.7 2.1 0.046 13.5 0.1 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Pyr_redox PF00070.27 PVD31611.1 - 0.013 16.1 0.3 0.037 14.6 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PVD31611.1 - 0.035 12.8 0.9 0.057 12.1 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein TRAPP PF04051.16 PVD31611.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Pyr_redox_3 PF13738.6 PVD31611.1 - 0.12 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amastin PF07344.11 PVD31611.1 - 2.8 7.8 10.8 0.12 12.2 0.1 3.2 3 0 0 3 3 3 0 Amastin surface glycoprotein TSP_1 PF00090.19 PVD31613.1 - 6.6e-09 35.8 3.6 1.3e-08 34.9 3.6 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain Ig_3 PF13927.6 PVD31615.1 - 0.011 16.3 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 PVD31615.1 - 0.12 12.5 0.0 9.5 6.5 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin domain Clathrin PF00637.20 PVD31619.1 - 3.4e-193 633.3 48.4 6e-34 117.0 3.3 9.1 8 1 1 9 9 9 8 Region in Clathrin and VPS Clathrin_propel PF01394.20 PVD31619.1 - 1.2e-48 161.2 3.3 1.1e-07 31.8 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 PVD31619.1 - 2e-34 117.3 2.0 6.6e-34 115.6 1.2 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 PVD31619.1 - 5.3e-13 48.1 0.1 1.8e-12 46.4 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 PVD31619.1 - 1.1e-07 31.3 6.2 1.1e-05 24.7 0.1 4.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 PVD31619.1 - 2.1e-05 24.2 9.5 0.89 9.7 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31619.1 - 2.6e-05 24.6 3.7 0.34 11.4 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD31619.1 - 0.00034 20.8 2.2 0.32 11.2 0.0 5.7 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD31619.1 - 0.00071 20.2 9.1 5.7 8.0 0.1 7.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31619.1 - 0.0066 16.5 10.9 1.9 8.8 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD31619.1 - 0.022 15.1 0.6 42 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31619.1 - 0.46 10.4 0.0 0.46 10.4 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Med21 PF11221.8 PVD31620.1 - 6.1e-29 101.1 7.2 2.2e-28 99.3 7.2 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.11 PVD31620.1 - 8.9e-05 21.7 1.9 0.00012 21.3 1.9 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) MCD PF05292.11 PVD31620.1 - 0.045 13.3 0.2 0.072 12.7 0.2 1.3 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain FUSC PF04632.12 PVD31620.1 - 0.37 9.3 3.1 0.44 9.0 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 PVD31620.1 - 0.42 10.7 5.4 0.49 10.5 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 PVD31620.1 - 1.8 8.9 12.9 0.35 11.2 8.9 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.19 PVD31621.1 - 4.2e-26 91.3 15.2 6.2e-26 90.8 15.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 PVD31621.1 - 0.0099 14.4 0.6 0.011 14.2 0.6 1.0 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein Malectin PF11721.8 PVD31622.1 - 1.7e-40 138.8 0.0 2.3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Malectin domain EB PF01683.18 PVD31623.1 - 0.015 15.6 0.1 0.02 15.2 0.1 1.4 1 0 0 1 1 1 0 EB module RWD PF05773.22 PVD31625.1 - 2.7e-17 63.1 0.0 9.4e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 PVD31625.1 - 8.1e-07 29.3 9.2 5.5e-06 26.6 9.2 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PVD31625.1 - 1.9e-05 24.3 10.6 4.3e-05 23.2 10.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PVD31625.1 - 0.0017 18.2 6.2 0.0085 16.0 6.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD31625.1 - 0.0036 17.3 0.7 0.0036 17.3 0.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD31625.1 - 0.0042 17.0 10.1 0.012 15.5 10.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Papo_T_antigen PF02380.15 PVD31625.1 - 0.0089 16.1 3.2 0.022 14.9 3.2 1.6 1 0 0 1 1 1 1 T-antigen specific domain zf-C3HC4_2 PF13923.6 PVD31625.1 - 0.27 11.1 10.5 0.045 13.6 4.9 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNTTIP1_dimer PF18192.1 PVD31626.1 - 2e-25 88.9 0.9 3.5e-25 88.1 0.9 1.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain adh_short_C2 PF13561.6 PVD31627.1 - 1.4e-49 168.7 0.0 2.1e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD31627.1 - 1.5e-47 161.6 0.1 2.1e-47 161.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF525 PF04379.14 PVD31627.1 - 1.4e-28 98.9 0.3 2.5e-28 98.1 0.3 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 PVD31627.1 - 8.9e-12 45.4 0.5 2.7e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like KR PF08659.10 PVD31627.1 - 1.9e-08 34.4 0.1 3.3e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Sulfotransfer_1 PF00685.27 PVD31628.1 - 3.5e-32 111.9 0.2 1.1e-31 110.3 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31628.1 - 0.0031 17.9 0.1 0.0067 16.8 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family Colipase_C PF02740.14 PVD31630.1 - 1.4e-12 47.6 12.8 0.00014 21.9 1.4 3.4 3 0 0 3 3 3 3 Colipase, C-terminal domain MIT_LIKE_ACTX PF17556.2 PVD31630.1 - 0.011 16.3 20.9 0.22 12.2 0.6 4.0 4 0 0 4 4 4 0 MIT-like atracotoxin family Prokineticin PF06607.11 PVD31630.1 - 0.017 15.4 19.1 0.11 12.8 6.1 3.5 1 1 2 3 3 3 0 Prokineticin zf-U11-48K PF05253.12 PVD31630.1 - 7.5 6.6 0.0 7.5 6.6 0.0 5.7 9 0 0 9 9 9 0 U11-48K-like CHHC zinc finger RRM_1 PF00076.22 PVD31631.1 - 5.9e-31 106.1 0.2 2.2e-16 59.4 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 PVD31631.1 - 5.6e-05 22.5 1.0 0.00012 21.4 1.0 1.5 1 0 0 1 1 1 1 Lsm interaction motif LSM_int_assoc PF16605.5 PVD31631.1 - 0.00017 21.7 4.9 0.0005 20.1 4.9 1.8 1 0 0 1 1 1 1 LSM-interacting associated unstructured RRM_7 PF16367.5 PVD31631.1 - 0.11 12.6 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif RNase_H2-Ydr279 PF09468.10 PVD31631.1 - 0.16 12.1 1.4 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Suf PF05843.14 PVD31631.1 - 0.29 11.1 12.6 1.6 8.7 0.0 4.2 4 2 0 4 4 4 0 Suppressor of forked protein (Suf) GPCR_chapero_1 PF11904.8 PVD31631.1 - 3 7.2 9.1 0.11 11.9 2.4 1.9 2 0 0 2 2 2 0 GPCR-chaperone DASH_Spc19 PF08287.11 PVD31631.1 - 8.5 6.2 15.9 4.8 7.1 0.0 3.4 3 0 0 3 3 3 0 Spc19 mit_SMPDase PF14724.6 PVD31632.1 - 2.5e-105 353.2 0.3 3.8e-105 352.6 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase VWD PF00094.25 PVD31633.1 - 2.3e-19 70.2 4.1 1.2e-08 35.4 0.0 4.4 4 0 0 4 4 4 3 von Willebrand factor type D domain Ldl_recept_a PF00057.18 PVD31633.1 - 6.8e-17 61.4 51.3 6.9e-09 35.8 8.7 10.4 10 1 1 11 11 11 3 Low-density lipoprotein receptor domain class A C8 PF08742.11 PVD31633.1 - 8.3e-09 35.8 19.3 1.1e-06 28.9 7.3 5.4 5 0 0 5 5 5 2 C8 domain TIL PF01826.17 PVD31633.1 - 3.4e-08 33.6 15.9 3.4e-08 33.6 15.9 13.5 10 2 3 13 13 13 2 Trypsin Inhibitor like cysteine rich domain TSP_1 PF00090.19 PVD31634.1 - 4.3e-05 23.6 8.5 4.3e-05 23.6 8.5 5.1 5 0 0 5 5 5 3 Thrombospondin type 1 domain Phospholip_A2_2 PF05826.12 PVD31635.1 - 8.2e-20 70.8 1.5 9.3e-20 70.7 1.5 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 PVD31635.1 - 1.5 9.3 8.2 3.9 8.0 8.2 1.8 1 1 0 1 1 1 0 Phospholipase A2 PALP PF00291.25 PVD31636.1 - 1.2e-59 202.1 0.5 1.9e-59 201.5 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF438 PF04282.13 PVD31636.1 - 0.012 15.5 1.6 0.096 12.6 1.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF438) Death PF00531.22 PVD31637.1 - 2.6e-06 27.5 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Death domain LPMO_10 PF03067.15 PVD31638.1 - 1.3e-12 48.8 0.0 2.5e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-RRN7 PF11781.8 PVD31638.1 - 0.044 13.5 0.3 0.13 12.0 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SAM_2 PF07647.17 PVD31643.1 - 3.5e-26 91.1 0.0 1.3e-12 47.6 0.0 3.2 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD31643.1 - 2e-18 66.6 0.1 2.5e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 PVD31643.1 - 1.2e-11 45.2 0.1 5.2e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 PVD31643.1 - 0.011 15.6 0.0 0.084 12.7 0.1 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD31643.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Arm PF00514.23 PVD31643.1 - 0.034 14.2 2.0 20 5.4 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HA2 PF04408.23 PVD31644.1 - 9.8e-14 51.6 0.4 6e-13 49.0 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 PVD31644.1 - 2.5e-06 27.4 0.1 1.4e-05 24.9 0.1 2.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD31644.1 - 5.3e-05 23.5 0.5 0.01 16.2 0.1 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 PVD31644.1 - 0.0017 18.1 0.0 0.0051 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD31644.1 - 0.0017 18.6 4.8 0.0048 17.2 0.1 3.6 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.9 PVD31644.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 PVD31644.1 - 0.014 14.3 1.5 3 6.7 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain AAA_23 PF13476.6 PVD31644.1 - 0.015 15.8 8.8 0.28 11.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain Helicase_RecD PF05127.14 PVD31644.1 - 0.02 14.8 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 Helicase RsgA_GTPase PF03193.16 PVD31644.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 PVD31644.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD31644.1 - 0.11 13.0 2.1 0.25 11.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter DUF87 PF01935.17 PVD31644.1 - 0.27 11.3 1.6 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain RRM_1 PF00076.22 PVD31645.1 - 7.9e-05 22.4 0.7 0.0018 18.1 0.1 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.6 PVD31646.1 - 0.0066 15.9 2.4 0.7 9.5 0.2 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 PVD31646.1 - 0.0091 15.9 6.6 1 9.4 0.2 4.2 3 1 1 4 4 4 2 EF-hand domain Nucleolin_bd PF16725.5 PVD31646.1 - 0.013 15.1 2.9 0.029 14.0 0.1 2.2 2 0 0 2 2 2 0 Nucleolin binding domain EF-hand_7 PF13499.6 PVD31646.1 - 0.018 15.5 1.3 0.31 11.5 0.6 2.7 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 PVD31646.1 - 0.061 12.9 6.8 0.72 9.5 0.2 3.7 4 0 0 4 4 4 0 EF hand Na_sulph_symp PF00939.19 PVD31647.1 - 2.6e-80 270.8 6.6 3.4e-80 270.4 6.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31647.1 - 1.7e-36 126.0 27.2 6.2e-18 65.0 0.4 3.0 2 1 1 3 3 3 3 Citrate transporter Sec1 PF00995.23 PVD31648.1 - 1.7e-124 417.2 0.0 1.9e-124 417.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RabGAP-TBC PF00566.18 PVD31649.1 - 1.7e-36 125.9 6.8 2.8e-34 118.7 2.7 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 PVD31649.1 - 8.1e-35 119.8 0.1 6e-34 117.0 0.0 2.7 2 1 1 3 3 3 1 Rab-binding domain (RBD) RUN PF02759.19 PVD31649.1 - 2.6e-32 111.6 0.4 8.8e-32 109.9 0.4 2.0 1 0 0 1 1 1 1 RUN domain Methyltransf_11 PF08241.12 PVD31650.1 - 2.6e-20 72.8 0.0 4.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD31650.1 - 6.2e-19 68.5 0.0 1.4e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD31650.1 - 4.8e-14 52.4 0.0 6.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD31650.1 - 1.2e-11 45.2 0.0 1.9e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD31650.1 - 2.2e-08 34.1 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD31650.1 - 1.5e-07 31.1 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PVD31650.1 - 1.6e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 PVD31650.1 - 1.8e-05 24.7 0.0 6.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 PVD31650.1 - 2.2e-05 24.2 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 PVD31650.1 - 0.00041 19.9 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 PVD31650.1 - 0.00053 19.5 0.0 0.0022 17.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 PVD31650.1 - 0.0054 16.2 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD31650.1 - 0.0087 15.6 0.0 0.031 13.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 PVD31650.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TPMT PF05724.11 PVD31650.1 - 0.013 15.2 0.0 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 PVD31650.1 - 0.015 15.3 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 PVD31650.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW KH_8 PF17903.1 PVD31650.1 - 0.045 13.8 0.0 0.94 9.6 0.0 2.3 2 0 0 2 2 2 0 Krr1 KH1 domain DUF938 PF06080.12 PVD31650.1 - 0.11 12.2 0.0 0.64 9.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF938) DUF4404 PF14357.6 PVD31651.1 - 0.039 14.6 0.0 0.17 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PRIMA1 PF16101.5 PVD31651.1 - 0.3 11.1 4.9 0.59 10.2 4.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Collagen PF01391.18 PVD31652.1 - 2.3e-12 46.4 36.5 1.8e-06 27.6 13.9 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) EMI PF07546.13 PVD31652.1 - 4.2 8.2 11.3 0.77 10.6 6.3 2.2 2 1 0 2 2 2 0 EMI domain GIT1_C PF12205.8 PVD31653.1 - 1e-38 132.0 1.4 1e-38 132.0 1.4 2.7 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term ArfGap PF01412.18 PVD31653.1 - 6.7e-28 97.1 1.4 9.4e-28 96.6 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 PVD31653.1 - 5.3e-25 86.7 4.3 5.5e-13 48.3 0.1 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT_CC PF16559.5 PVD31653.1 - 1.6e-13 50.3 10.5 1.3e-12 47.4 3.2 3.2 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Ank_2 PF12796.7 PVD31653.1 - 2.5e-09 37.6 0.0 1.2e-08 35.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD31653.1 - 1e-06 29.2 0.1 0.0028 18.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD31653.1 - 1.8e-06 28.1 0.1 6.7e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD31653.1 - 0.015 15.7 0.0 6.6 7.6 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 PVD31653.1 - 0.016 15.6 0.1 3.9 8.1 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat TTRAP PF14203.6 PVD31653.1 - 0.023 14.7 0.7 0.21 11.6 0.1 2.8 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein COG2 PF06148.11 PVD31653.1 - 0.06 13.4 9.2 0.48 10.5 1.0 3.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0449 PF15136.6 PVD31653.1 - 0.085 13.3 5.5 11 6.6 0.5 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 COG6 PF06419.11 PVD31653.1 - 0.72 8.0 8.4 0.19 9.9 2.6 2.2 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 YabA PF06156.13 PVD31653.1 - 1.1 9.9 9.2 0.59 10.8 3.2 3.0 3 0 0 3 3 2 0 Initiation control protein YabA ATG16 PF08614.11 PVD31653.1 - 1.2 9.3 13.3 2.4 8.3 2.4 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 PVD31653.1 - 2.6 8.0 12.2 0.05 13.6 3.3 2.5 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Dzip-like_N PF13815.6 PVD31653.1 - 2.8 7.9 6.0 1.5 8.8 0.8 2.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal TPR_MLP1_2 PF07926.12 PVD31653.1 - 4.2 7.4 12.8 0.48 10.5 1.3 3.2 4 0 0 4 4 3 0 TPR/MLP1/MLP2-like protein MnmE_helical PF12631.7 PVD31653.1 - 5.3 7.2 8.8 2.4 8.3 0.3 2.7 1 1 2 3 3 3 0 MnmE helical domain ParB PF08775.10 PVD31653.1 - 9.7 6.7 7.3 3.6 8.1 0.1 3.3 3 0 0 3 3 3 0 ParB family TMEM132 PF16070.5 PVD31654.1 - 1.2e-92 311.0 0.1 1.7e-92 310.4 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_N PF15705.5 PVD31654.1 - 1e-12 48.0 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132D_C PF15706.5 PVD31654.1 - 2.1e-07 30.6 0.0 4.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Arrestin_C PF02752.22 PVD31654.1 - 0.043 14.3 0.0 0.7 10.4 0.0 2.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain T2SS-T3SS_pil_N PF13629.6 PVD31654.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Pilus formation protein N terminal region ANF_receptor PF01094.28 PVD31655.1 - 1.8e-167 556.9 0.8 5.9e-37 127.6 0.0 5.2 5 0 0 5 5 5 5 Receptor family ligand binding region 7tm_3 PF00003.22 PVD31655.1 - 1.2e-30 107.0 20.2 2.8e-30 105.8 20.2 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 PVD31655.1 - 8.2e-23 81.6 13.1 6.3e-07 29.4 0.8 6.0 6 0 0 6 6 6 5 Periplasmic binding protein ANF_receptor PF01094.28 PVD31656.1 - 6.5e-142 472.8 28.8 4e-39 134.7 0.8 5.2 5 0 0 5 5 5 5 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD31656.1 - 2.1e-35 123.0 20.7 3.5e-10 40.1 0.1 5.8 5 1 0 5 5 5 5 Periplasmic binding protein 7tm_3 PF00003.22 PVD31656.1 - 2.3e-29 102.8 17.0 4.5e-29 101.8 17.0 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Competence PF03772.16 PVD31656.1 - 0.01 15.1 0.2 0.01 15.1 0.2 2.5 2 0 0 2 2 2 0 Competence protein Sugar_tr PF00083.24 PVD31657.1 - 3.9e-37 128.2 23.0 4.9e-37 127.9 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD31657.1 - 1.7e-33 116.0 39.2 2.5e-25 89.1 16.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD31657.1 - 0.0084 14.7 3.2 0.0084 14.7 3.2 4.6 2 2 1 4 4 4 3 MFS/sugar transport protein VWA PF00092.28 PVD31658.1 - 3.2e-13 50.3 0.1 3.5e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD31658.1 - 8.4e-08 32.8 0.0 9.2e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain FSH1 PF03959.13 PVD31658.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Astacin PF01400.24 PVD31659.1 - 1e-62 211.2 0.0 1.5e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 PVD31659.1 - 9.4e-23 80.9 0.0 1.7e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu CUB PF00431.20 PVD31659.1 - 8.4e-16 58.3 0.0 1.5e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 PVD31659.1 - 1.3e-14 54.1 26.7 4e-10 39.7 13.2 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Sushi PF00084.20 PVD31659.1 - 1.9e-07 31.6 0.4 5.2e-07 30.2 0.4 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) VWA PF00092.28 PVD31660.1 - 2e-90 301.7 8.2 7.8e-40 137.0 0.8 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 PVD31660.1 - 2e-35 121.7 2.4 1.8e-18 67.1 0.3 3.5 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD31660.1 - 2.3e-12 47.1 0.6 9e-05 22.5 0.1 3.8 3 1 0 3 3 3 2 von Willebrand factor type A domain vWA-TerF-like PF10138.9 PVD31660.1 - 4.6e-08 33.4 3.9 0.00093 19.3 0.4 2.9 3 0 0 3 3 3 2 vWA found in TerF C terminus Copine PF07002.16 PVD31660.1 - 0.0037 16.7 0.5 1.5 8.2 0.1 3.0 3 0 0 3 3 3 1 Copine NOG1 PF06858.14 PVD31660.1 - 0.0081 15.9 0.0 15 5.5 0.1 4.2 4 0 0 4 4 4 1 Nucleolar GTP-binding protein 1 (NOG1) CxC1 PF18802.1 PVD31660.1 - 0.044 13.9 0.4 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Metalloenzyme PF01676.18 PVD31660.1 - 0.067 12.5 0.1 5 6.4 0.0 2.6 3 0 0 3 3 3 0 Metalloenzyme superfamily ILEI PF15711.5 PVD31660.1 - 0.2 12.1 0.8 1.4 9.5 0.4 2.6 3 0 0 3 3 3 0 Interleukin-like EMT inducer Mucin PF01456.17 PVD31660.1 - 0.96 9.4 22.8 0.49 10.4 19.7 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Sulfatase PF00884.23 PVD31661.1 - 4.1e-53 180.8 0.0 1.4e-52 179.0 0.0 1.8 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD31661.1 - 1.1e-14 54.6 4.3 7.3e-10 39.0 1.4 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 PVD31661.1 - 0.0026 18.5 0.0 0.007 17.1 0.1 1.7 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase STI1 PF17830.1 PVD31661.1 - 0.0035 17.2 0.2 0.17 11.8 0.1 2.5 2 0 0 2 2 2 1 STI1 domain DUF1501 PF07394.12 PVD31661.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase PF00884.23 PVD31662.1 - 4.6e-40 137.9 0.2 2.3e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 PVD31662.1 - 1.8e-12 47.4 1.0 1.7e-09 37.9 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 PVD31662.1 - 2.4e-07 30.7 0.0 1.8e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 PVD31662.1 - 0.12 11.4 0.0 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.6 PVD31662.1 - 0.12 13.1 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD31662.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function ABC_tran PF00005.27 PVD31663.1 - 1.5e-29 103.3 0.0 3.1e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PVD31663.1 - 2.2e-29 102.4 21.9 3.2e-29 101.8 21.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 PVD31663.1 - 6.1e-05 23.0 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PVD31663.1 - 0.00024 20.8 0.2 0.00094 18.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 PVD31663.1 - 0.00044 19.7 0.7 0.36 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PVD31663.1 - 0.0005 19.8 0.6 0.02 14.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PVD31663.1 - 0.0011 18.9 0.1 0.0023 17.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 PVD31663.1 - 0.0024 18.4 0.0 0.0079 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD31663.1 - 0.0029 18.0 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 PVD31663.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PVD31663.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 PVD31663.1 - 0.025 14.8 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PVD31663.1 - 0.034 14.6 0.0 0.089 13.2 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PVD31663.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD31663.1 - 0.12 12.2 0.1 0.83 9.4 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 PVD31663.1 - 0.22 11.8 0.1 0.42 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 PVD31664.1 - 9.9e-30 103.8 20.3 1.4e-29 103.3 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD31664.1 - 3.5e-28 98.6 28.8 4.3e-18 65.4 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 PVD31665.1 - 2.5e-93 312.1 0.0 3.3e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD31665.1 - 5.2e-39 134.2 0.0 1.3e-38 132.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 PVD31665.1 - 1.7e-21 76.6 3.4 4.2e-10 40.1 1.2 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD31665.1 - 4e-18 65.3 0.5 7.1e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD31665.1 - 1.2e-14 54.4 3.4 7.3e-07 29.4 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD31665.1 - 1.7e-13 50.5 5.7 7.6e-06 26.0 0.1 3.2 2 1 1 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD31665.1 - 2.2e-13 50.3 5.4 0.00011 22.3 0.3 4.4 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD31665.1 - 4.8e-05 23.5 0.2 0.33 11.2 0.0 2.6 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD31665.1 - 0.00023 21.5 0.8 0.053 13.9 0.1 2.7 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 PVD31665.1 - 0.0008 19.4 2.6 0.011 15.8 0.4 3.0 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Kinase-like PF14531.6 PVD31665.1 - 0.0015 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ig_C17orf99 PF17736.1 PVD31665.1 - 0.0027 17.7 0.1 0.062 13.4 0.1 2.9 2 1 0 2 2 2 1 C17orf99 Ig domain Protocadherin PF08374.11 PVD31665.1 - 0.0081 16.2 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Protocadherin Rax2 PF12768.7 PVD31665.1 - 0.038 13.5 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4386 PF14329.6 PVD31665.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) EphA2_TM PF14575.6 PVD31665.1 - 0.071 14.0 0.1 0.19 12.7 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TPR_MLP1_2 PF07926.12 PVD31666.1 - 0.0031 17.5 29.9 0.0031 17.5 29.9 4.6 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 PVD31666.1 - 0.013 15.6 9.4 0.013 15.6 9.4 6.2 4 1 2 6 6 6 0 bZIP transcription factor zf-C2H2 PF00096.26 PVD31666.1 - 0.028 14.9 0.3 0.12 12.9 0.3 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type FUSC PF04632.12 PVD31666.1 - 0.15 10.6 6.7 0.29 9.6 6.7 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 PVD31666.1 - 3.3 7.5 77.6 0.12 12.2 30.9 3.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 PVD31666.1 - 5.2 6.4 77.0 0.058 12.7 25.8 4.5 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PVD31666.1 - 8.4 5.2 73.5 3.1 6.6 28.3 4.5 2 1 2 4 4 4 0 Spc7 kinetochore protein ABC_trans_N PF14510.6 PVD31666.1 - 8.5 7.1 10.6 0.27 11.9 1.7 3.0 3 0 0 3 3 3 0 ABC-transporter N-terminal PALP PF00291.25 PVD31667.1 - 1.7e-51 175.4 0.1 2e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UQ_con PF00179.26 PVD31668.1 - 7.5e-45 152.0 0.2 8.5e-45 151.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PVD31668.1 - 0.00032 20.6 0.1 0.00048 20.0 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PVD31668.1 - 0.00046 20.5 0.2 0.00077 19.7 0.2 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 PVD31668.1 - 0.0013 18.4 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1154 PF06631.11 PVD31668.1 - 0.42 10.7 5.9 0.39 10.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) SH2_2 PF14633.6 PVD31669.1 - 1.3e-86 289.5 2.7 1.3e-86 289.5 2.7 2.5 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 PVD31669.1 - 1.3e-44 151.6 0.1 2.9e-44 150.5 0.1 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 PVD31669.1 - 2.8e-41 140.1 0.0 5.6e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 PVD31669.1 - 8e-24 84.3 5.1 2.2e-23 82.9 5.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 Tex_N PF09371.10 PVD31669.1 - 5.6e-10 39.2 0.3 0.0019 17.9 0.0 3.4 2 1 0 2 2 2 2 Tex-like protein N-terminal domain S1 PF00575.23 PVD31669.1 - 3.3e-09 36.9 0.1 7.7e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 PVD31669.1 - 1.5e-08 34.7 0.0 4.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 PVD31669.1 - 7.1e-08 32.9 24.3 7.1e-08 32.9 24.3 6.7 5 2 2 7 7 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 PVD31669.1 - 1.2e-06 28.5 0.0 5e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Tex_YqgF PF16921.5 PVD31669.1 - 4.5e-06 27.1 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 PVD31669.1 - 9e-06 26.5 0.4 4.8e-05 24.2 0.4 2.4 1 0 0 1 1 1 1 HHH domain GETHR PF05671.11 PVD31669.1 - 7.3e-05 22.0 9.9 0.00013 21.2 9.9 1.4 1 0 0 1 1 1 1 GETHR pentapeptide repeat (5 copies) Astacin PF01400.24 PVD31670.1 - 9.1e-58 195.0 0.1 1.8e-57 194.1 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MFS_1 PF07690.16 PVD31670.1 - 1.3e-12 47.3 21.0 2.9e-12 46.2 3.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PVD31670.1 - 5.4e-09 35.9 6.7 1.7e-08 34.3 6.7 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 ShK PF01549.24 PVD31670.1 - 9.7e-08 32.4 39.7 1e-05 25.9 9.9 3.6 3 0 0 3 3 3 2 ShK domain-like Peptidase_M10 PF00413.24 PVD31670.1 - 0.00032 20.6 0.2 0.81 9.5 0.0 3.1 3 0 0 3 3 3 2 Matrixin MAGI_u5 PF16666.5 PVD31670.1 - 0.041 14.0 0.2 0.041 14.0 0.2 2.4 2 0 0 2 2 2 0 Unstructured region on MAGI UNC-93 PF05978.16 PVD31671.1 - 4.6e-08 32.9 5.1 4.6e-08 32.9 5.1 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 PVD31671.1 - 4.2e-07 29.2 38.3 1e-05 24.7 18.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4605 PF15378.6 PVD31671.1 - 2 8.3 7.4 3.8 7.4 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) DUF3439 PF11921.8 PVD31672.1 - 0.013 15.5 10.7 0.028 14.4 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 PVD31672.1 - 0.2 9.6 0.7 0.2 9.6 0.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Adeno_PIX PF03955.14 PVD31672.1 - 1.9 8.7 7.3 8.9 6.5 2.2 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Med3 PF11593.8 PVD31672.1 - 5.4 6.1 10.4 8.6 5.4 10.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nucleos_tra2_C PF07662.13 PVD31673.1 - 1.8e-72 243.5 3.1 1.8e-72 243.5 3.1 2.6 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 PVD31673.1 - 4e-15 56.2 2.9 4e-15 56.2 2.9 3.5 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 PVD31673.1 - 0.0012 19.1 8.8 0.0012 19.1 8.8 4.0 3 1 0 3 3 3 1 Nucleoside recognition TMEM43 PF07787.12 PVD31673.1 - 0.097 12.0 3.2 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 43 Glyco_hydro_63 PF03200.16 PVD31674.1 - 5.6e-12 45.2 6.4 8.1e-06 24.9 0.9 4.7 4 1 0 4 4 4 3 Glycosyl hydrolase family 63 C-terminal domain DUF2179 PF10035.9 PVD31674.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) eRF1_1 PF03463.15 PVD31675.1 - 8.3e-50 168.1 0.2 1.4e-49 167.4 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 PVD31675.1 - 1.4e-34 119.3 0.0 2.5e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PVD31675.1 - 9.5e-27 93.7 0.0 2.1e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 AAA_31 PF13614.6 PVD31675.1 - 0.027 14.4 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rep_fac-A_C PF08646.10 PVD31676.1 - 1.2e-52 177.5 8.8 6e-51 172.0 6.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PVD31676.1 - 8.6e-34 115.4 0.4 1.9e-33 114.2 0.4 1.6 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 PVD31676.1 - 8.6e-11 41.7 0.9 3e-10 39.9 0.0 2.3 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 PVD31676.1 - 1.9e-07 31.0 0.2 4.8e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain IBR PF01485.21 PVD31676.1 - 0.025 14.8 4.4 0.059 13.6 4.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF223 PF02721.14 PVD31676.1 - 0.057 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF223 Pox_vIL-18BP PF05566.12 PVD31676.1 - 0.065 13.5 0.4 6.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein CDC24_OB3 PF17244.2 PVD31676.1 - 0.099 12.3 2.4 2.6 7.7 0.1 3.0 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 DUF3970 PF13113.6 PVD31676.1 - 0.11 12.7 0.8 0.48 10.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) DUF2452 PF10504.9 PVD31677.1 - 7.9e-71 236.6 0.6 1e-70 236.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) RWD PF05773.22 PVD31678.1 - 3.3e-16 59.6 0.2 5.9e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 RWD domain SNF2_N PF00176.23 PVD31679.1 - 3.3e-46 157.6 0.3 9.2e-46 156.1 0.3 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD31679.1 - 9.3e-20 71.0 0.1 2.2e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD31679.1 - 9.5e-08 32.2 0.0 9.5e-08 32.2 0.0 4.5 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 PVD31679.1 - 5.3e-06 25.5 0.1 1.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 HDA2-3 PF11496.8 PVD31679.1 - 0.00084 18.6 0.0 0.0025 17.0 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF3157 PF11355.8 PVD31679.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) SNF2_N PF00176.23 PVD31680.1 - 4.7e-47 160.4 0.0 3.4e-46 157.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD31680.1 - 2.3e-19 69.8 0.1 1.8e-17 63.7 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD31680.1 - 3.5e-08 33.6 0.4 2.4e-07 30.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 PVD31680.1 - 0.00043 19.3 0.3 0.0012 17.8 0.1 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 TPR_12 PF13424.6 PVD31680.1 - 0.0015 18.8 2.0 0.16 12.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31680.1 - 0.023 14.5 4.3 0.077 12.8 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SWI2_SNF2 PF18766.1 PVD31680.1 - 0.049 13.3 0.0 0.3 10.7 0.0 2.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase TPR_2 PF07719.17 PVD31680.1 - 0.054 13.6 3.4 0.083 13.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31680.1 - 0.08 13.2 0.5 0.36 11.2 0.5 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 PVD31680.1 - 0.096 13.1 0.2 9.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 PVD31680.1 - 0.097 12.6 1.2 9 6.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD31680.1 - 0.13 13.0 0.2 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31680.1 - 0.57 10.3 2.0 19 5.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IML1 PF12257.8 PVD31681.1 - 2.9e-109 364.6 0.3 4.6e-109 364.0 0.3 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 PVD31681.1 - 1.1e-05 25.4 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPR_2 PF07719.17 PVD31682.1 - 2.1e-07 30.5 4.2 0.021 14.9 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31682.1 - 0.0022 17.7 5.0 0.21 11.4 0.9 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 PVD31682.1 - 0.0072 16.4 0.3 0.02 15.0 0.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 PVD31682.1 - 0.03 14.6 0.2 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 PVD31682.1 - 0.041 13.4 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 PVD31682.1 - 0.33 10.7 3.6 2.7 7.8 1.3 2.9 3 0 0 3 3 3 0 TPR repeat Abhydrolase_1 PF00561.20 PVD31683.1 - 7.3e-17 61.8 0.1 2.2e-13 50.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD31683.1 - 6.6e-12 46.5 0.0 8.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD31683.1 - 3.3e-07 29.8 0.0 5.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PVD31683.1 - 7.9e-07 28.1 0.0 1.4e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 PVD31683.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 PVD31683.1 - 0.0032 17.2 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein PAF-AH_p_II PF03403.13 PVD31683.1 - 0.027 13.0 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1749 PF08538.10 PVD31683.1 - 0.036 13.2 0.0 0.06 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 PVD31683.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 PVD31683.1 - 0.052 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Helicase_C PF00271.31 PVD31684.1 - 2.7e-15 56.6 0.1 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PVD31684.1 - 7.3e-10 39.1 0.0 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PVD31684.1 - 4.1e-09 36.7 0.5 1.5e-07 31.7 0.0 3.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 PVD31684.1 - 0.00013 21.8 0.6 0.00094 19.0 0.4 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PVD31684.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD31684.1 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD31684.1 - 0.01 16.1 0.0 0.092 13.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PVD31684.1 - 0.021 14.8 0.1 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase RRM_1 PF00076.22 PVD31684.1 - 0.026 14.4 0.2 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD31684.1 - 0.083 12.9 1.9 0.16 12.1 0.1 2.5 2 0 0 2 2 1 0 RNA binding motif AAA_29 PF13555.6 PVD31684.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PVD31684.1 - 0.75 10.3 0.0 0.75 10.3 0.0 4.2 4 1 0 4 4 4 0 AAA domain Helicase_C PF00271.31 PVD31685.1 - 5.8e-16 58.8 1.6 1.2e-14 54.6 0.1 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HA2 PF04408.23 PVD31685.1 - 6.1e-13 49.0 0.0 3.6e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD31685.1 - 4.3e-12 46.2 0.0 2.2e-11 43.9 0.0 2.3 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold IBR PF01485.21 PVD31685.1 - 6.1e-10 39.2 23.9 1.2e-06 28.6 2.8 5.4 6 0 0 6 6 6 2 IBR domain, a half RING-finger domain DEAD PF00270.29 PVD31685.1 - 3.7e-06 26.8 0.2 4.8e-05 23.2 0.1 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SLS PF14611.6 PVD31685.1 - 0.0021 17.9 0.0 0.086 12.7 0.0 2.6 1 1 1 2 2 2 1 Mitochondrial inner-membrane-bound regulator RRM_1 PF00076.22 PVD31685.1 - 0.0053 16.6 0.2 0.035 13.9 0.2 2.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_30 PF13604.6 PVD31685.1 - 0.0063 16.3 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD31685.1 - 0.0097 16.2 4.6 0.015 15.5 0.1 3.6 5 0 0 5 5 5 1 AAA domain Helicase_RecD PF05127.14 PVD31685.1 - 0.11 12.3 0.0 0.42 10.4 0.0 2.1 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.6 PVD31685.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD31685.1 - 0.15 12.6 0.0 0.68 10.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 PVD31685.1 - 0.75 10.3 0.0 0.75 10.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain VWA PF00092.28 PVD31686.1 - 3.9e-40 137.9 0.0 1.6e-33 116.4 0.0 2.9 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 PVD31687.1 - 6.1e-40 137.3 0.2 2.3e-35 122.4 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD31687.1 - 1.4e-11 45.0 0.0 6.1e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD31687.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PVD31687.1 - 0.013 14.7 0.2 0.093 11.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1194) THF_DHG_CYH PF00763.23 PVD31687.1 - 0.017 15.4 0.0 0.67 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain LEM PF03020.15 PVD31688.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 LEM domain DUF1917 PF08939.10 PVD31688.1 - 0.19 11.6 0.0 0.21 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) RVT_1 PF00078.27 PVD31689.1 - 2.2e-26 92.8 0.1 3.9e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 PVD31689.1 - 0.0013 18.9 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 PVD31689.1 - 0.01 15.9 1.2 0.01 15.9 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle TRAM_LAG1_CLN8 PF03798.16 PVD31690.1 - 4e-12 46.3 21.9 4e-12 46.3 21.9 1.8 2 0 0 2 2 2 1 TLC domain PIG-P PF08510.12 PVD31690.1 - 7.3 6.5 10.8 25 4.8 1.2 3.8 3 1 1 4 4 4 0 PIG-P PIP49_C PF12260.8 PVD31691.1 - 1.6e-07 31.2 0.0 5.9e-07 29.3 0.0 2.0 3 0 0 3 3 3 1 Protein-kinase domain of FAM69 CDC4_D PF16856.5 PVD31691.1 - 0.056 13.3 1.0 5.1 7.1 0.1 3.2 3 0 0 3 3 3 0 Cell division control protein 4 dimerisation domain Spt5_N PF11942.8 PVD31691.1 - 0.43 11.6 2.0 1.8 9.6 0.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Acyl-CoA_dh_1 PF00441.24 PVD31692.1 - 3.9e-27 95.3 0.6 3.9e-27 95.3 0.6 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 PVD31692.1 - 4.8e-20 72.1 0.0 9.4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD31692.1 - 3.4e-15 56.0 0.1 7e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD31692.1 - 3.2e-06 27.5 0.3 1.2e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 PVD31693.1 - 7.1e-65 219.0 0.0 1.4e-64 218.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31693.1 - 2.2e-32 112.4 0.0 1.3e-30 106.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD31693.1 - 8.9e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD31693.1 - 1.7e-06 27.1 0.2 3.9e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD31693.1 - 0.08 12.8 0.5 0.99 9.3 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD31693.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 PVD31696.1 - 3e-13 49.4 23.8 6.5e-08 31.9 12.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD31696.1 - 1.5e-09 37.3 13.0 1.6e-07 30.6 4.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD31696.1 - 0.0056 15.3 4.4 0.0056 15.3 4.4 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein TMEM70 PF06979.12 PVD31696.1 - 0.029 14.8 0.2 0.12 12.8 0.2 2.0 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Astacin PF01400.24 PVD31697.1 - 1.9e-64 216.8 0.1 1.9e-64 216.8 0.1 1.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) ShK PF01549.24 PVD31697.1 - 1.6e-06 28.5 11.3 1.6e-06 28.5 11.3 3.5 3 0 0 3 3 3 1 ShK domain-like Peptidase_M10 PF00413.24 PVD31697.1 - 5.8e-06 26.2 0.3 0.09 12.6 0.1 2.5 2 0 0 2 2 2 2 Matrixin DUF3152 PF11350.8 PVD31697.1 - 0.00013 21.7 0.6 0.62 9.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3152) Peptidase_M66 PF10462.9 PVD31697.1 - 0.0065 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.8 PVD31697.1 - 0.2 11.2 6.1 0.97 9.0 2.9 2.8 2 1 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 PVD31698.1 - 2.8e-68 229.3 0.1 4.5e-68 228.6 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 PVD31698.1 - 1.3e-07 32.0 10.9 1.3e-07 32.0 10.9 2.4 2 0 0 2 2 2 1 ShK domain-like Peptidase_M10 PF00413.24 PVD31698.1 - 3.2e-05 23.8 0.4 0.055 13.3 0.1 2.3 2 0 0 2 2 2 2 Matrixin Peptidase_M66 PF10462.9 PVD31698.1 - 0.0094 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 PVD31698.1 - 0.02 15.4 0.1 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 PVD31698.1 - 0.029 14.0 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M14 PF00246.24 PVD31699.1 - 4.5e-225 745.4 0.8 6.5e-81 272.3 0.1 5.2 4 1 1 5 5 5 5 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 PVD31699.1 - 9.7e-40 134.7 10.8 3.8e-13 49.5 0.3 4.7 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PVD31699.1 - 1.2e-22 79.7 7.2 1.6e-05 24.8 0.1 4.5 4 0 0 4 4 4 4 CarboxypepD_reg-like domain AstE_AspA PF04952.14 PVD31699.1 - 2.3e-13 49.9 1.2 0.00013 21.2 0.0 4.6 4 0 0 4 4 4 3 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.11 PVD31699.1 - 6.9e-12 45.1 0.2 0.01 15.7 0.0 4.7 4 0 0 4 4 4 4 PEGA domain fn3_3 PF14686.6 PVD31699.1 - 5.6e-05 22.8 0.6 2.3 8.0 0.0 3.8 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II Acetyltransf_4 PF13420.7 PVD31699.1 - 0.009 16.2 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Big_9 PF17963.1 PVD31699.1 - 0.038 14.7 1.9 0.073 13.8 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig domain DUF1533 PF07550.11 PVD31699.1 - 0.061 13.2 0.0 11 6.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1533) Y_Y_Y PF07495.13 PVD31699.1 - 0.063 13.2 0.2 17 5.5 0.1 3.3 3 0 0 3 3 3 0 Y_Y_Y domain Urease_linker PF18473.1 PVD31699.1 - 0.067 13.1 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain DUF1416 PF07210.12 PVD31699.1 - 0.11 12.4 0.0 14 5.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) PAC2 PF09754.9 PVD31699.1 - 0.16 12.0 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 PAC2 family phage_tail_N PF08400.10 PVD31699.1 - 0.18 11.8 0.2 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Prophage tail fibre N-terminal ACOX PF01756.19 PVD31700.1 - 3.4e-48 163.6 0.0 5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PVD31700.1 - 5.7e-18 64.9 0.0 9.4e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PVD31700.1 - 3.9e-08 33.6 0.0 1.6e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD31700.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 PVD31701.1 - 1.6e-10 40.7 0.0 7.4e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 PVD31701.1 - 7.9e-06 25.1 6.9 1.1e-05 24.6 6.9 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PT PF04886.12 PVD31704.1 - 1.8 8.2 14.9 0.073 12.6 4.4 3.1 2 2 0 2 2 2 0 PT repeat Tweety PF04906.13 PVD31706.1 - 0.076 11.7 0.0 0.076 11.7 0.0 1.4 2 0 0 2 2 2 0 Tweety dsrm PF00035.26 PVD31708.1 - 4.5e-15 56.1 1.1 4.8e-09 36.8 0.1 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif OLF PF02191.16 PVD31709.1 - 5e-69 232.6 1.1 8.2e-69 231.9 1.1 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain CUE PF02845.16 PVD31710.1 - 2.6e-13 49.4 0.2 4.7e-13 48.6 0.2 1.4 1 0 0 1 1 1 1 CUE domain HECT PF00632.25 PVD31711.1 - 9.7e-94 314.3 0.0 1.9e-93 313.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 PVD31711.1 - 5.6e-05 22.6 1.2 0.00024 20.6 0.0 2.7 3 0 0 3 3 3 1 IQ calmodulin-binding motif Nexin_C PF08628.12 PVD31711.1 - 0.019 15.6 0.0 0.074 13.6 0.0 2.0 1 0 0 1 1 1 0 Sorting nexin C terminal zf-C3HC4 PF00097.25 PVD31712.1 - 8.2e-08 32.0 7.1 2.3e-07 30.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD31712.1 - 1.1e-06 28.4 7.1 4.3e-06 26.5 7.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD31712.1 - 2.5e-06 27.2 8.7 5.8e-06 26.1 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD31712.1 - 2e-05 24.5 4.2 2e-05 24.5 4.2 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD31712.1 - 3.5e-05 24.1 8.7 3.5e-05 24.1 8.7 2.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD31712.1 - 7.3e-05 22.7 8.0 8.5e-05 22.4 6.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD31712.1 - 0.0012 19.0 6.9 0.0033 17.5 6.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING AIM3 PF17096.5 PVD31712.1 - 0.02 15.8 0.1 0.02 15.8 0.1 2.8 3 0 0 3 3 1 0 Altered inheritance of mitochondria protein 3 Prok-RING_4 PF14447.6 PVD31712.1 - 0.04 13.8 8.2 0.22 11.4 8.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 AAA_2 PF07724.14 PVD31712.1 - 0.088 12.9 0.7 12 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) zf-rbx1 PF12678.7 PVD31712.1 - 2 8.7 8.8 10 6.5 8.8 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain C2 PF00168.30 PVD31713.1 - 8.4e-49 164.1 0.3 2.3e-23 82.4 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 PVD31713.1 - 1.2e-34 119.1 2.1 3e-34 117.7 2.1 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 PVD31713.1 - 0.00017 21.7 5.8 0.00037 20.6 5.8 1.6 1 0 0 1 1 1 1 Piccolo Zn-finger FYVE PF01363.21 PVD31713.1 - 0.0099 16.0 3.1 0.023 14.8 3.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger UPF0167 PF03691.14 PVD31713.1 - 0.028 14.2 1.7 0.079 12.8 1.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Cript PF10235.9 PVD31713.1 - 0.068 13.7 1.1 0.26 11.9 1.1 2.0 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT PHD PF00628.29 PVD31713.1 - 1.2 9.0 9.0 0.65 9.9 6.8 1.8 2 0 0 2 2 2 0 PHD-finger Lipocalin_4 PF13648.6 PVD31713.1 - 1.4 9.9 7.3 0.8 10.7 0.1 3.0 2 1 0 2 2 2 0 Lipocalin-like domain zf-B_box PF00643.24 PVD31713.1 - 1.8 8.8 6.2 0.77 10.0 2.7 2.1 2 0 0 2 2 2 0 B-box zinc finger TBCC PF07986.12 PVD31714.1 - 1.8e-29 101.9 0.4 3.9e-29 100.8 0.4 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 PVD31714.1 - 5.4e-07 29.4 0.5 9.1e-07 28.6 0.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal ERp29_N PF07912.13 PVD31715.1 - 1.3e-36 125.6 0.4 1.3e-36 125.6 0.4 1.6 2 0 0 2 2 2 1 ERp29, N-terminal domain ERp29 PF07749.12 PVD31715.1 - 7.6e-18 65.2 1.1 1.9e-17 63.9 1.1 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain CDP-OH_P_transf PF01066.21 PVD31715.1 - 2.4e-12 47.4 0.2 2.4e-12 47.4 0.2 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ColG_sub PF18496.1 PVD31715.1 - 0.023 14.9 1.6 0.045 13.9 1.6 1.4 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain VWA_2 PF13519.6 PVD31715.1 - 0.04 14.6 0.0 0.17 12.5 0.0 2.1 3 0 0 3 3 3 0 von Willebrand factor type A domain Ribosomal_S15 PF00312.22 PVD31715.1 - 0.073 13.3 0.5 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S15 Thioredoxin_6 PF13848.6 PVD31715.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Ion_trans PF00520.31 PVD31716.1 - 5.6e-22 78.2 7.8 8.7e-22 77.5 7.8 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 PVD31716.1 - 3.9e-16 58.9 0.0 7.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD31716.1 - 0.0002 21.2 0.5 0.00046 20.1 0.5 1.6 1 0 0 1 1 1 1 Ion channel DUF3899 PF13038.6 PVD31716.1 - 0.12 12.9 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Homeodomain PF00046.29 PVD31717.1 - 9.1e-20 70.3 2.0 1.6e-19 69.4 2.0 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 PVD31717.1 - 5.8e-18 64.9 2.5 9e-18 64.3 2.5 1.3 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 PVD31717.1 - 2.7e-05 24.0 0.1 6.5e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Rib_recp_KP_reg PF05104.12 PVD31719.1 - 0.026 15.6 1.4 0.037 15.1 1.4 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF2781 PF10914.8 PVD31720.1 - 5e-22 78.9 16.1 5.8e-22 78.7 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) RRM_1 PF00076.22 PVD31721.1 - 1e-79 262.3 8.4 3.6e-18 65.1 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deamin PF02137.18 PVD31721.1 - 7.8e-71 239.2 0.1 3.4e-70 237.1 0.0 2.2 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain RRM_7 PF16367.5 PVD31721.1 - 1.5e-06 28.2 0.0 3.6 7.8 0.0 5.3 5 0 0 5 5 5 2 RNA recognition motif dsrm PF00035.26 PVD31721.1 - 2.3e-06 28.2 0.0 2.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif RRM_5 PF13893.6 PVD31721.1 - 3.1e-05 23.6 0.0 0.18 11.4 0.1 5.0 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.23 PVD31722.1 - 3.5e-06 26.7 0.0 5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD31722.1 - 0.0067 16.2 0.1 0.0089 15.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Na_sulph_symp PF00939.19 PVD31723.1 - 4.9e-95 319.3 16.7 6.6e-95 318.9 16.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD31723.1 - 2.6e-33 115.5 33.7 3.3e-20 72.5 5.2 3.0 2 1 1 3 3 3 3 Citrate transporter DctM PF06808.12 PVD31723.1 - 0.0032 16.3 21.6 0.011 14.6 6.7 2.6 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component DUF2681 PF10883.8 PVD31723.1 - 0.13 12.7 2.8 0.32 11.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF2207 PF09972.9 PVD31723.1 - 1.5 7.5 6.2 0.12 11.1 0.2 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Pro_dh PF01619.18 PVD31724.1 - 1.2e-57 195.8 0.1 1.5e-57 195.4 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Hira PF07569.11 PVD31725.1 - 1.5e-43 149.1 0.0 2.7e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 PVD31725.1 - 7.2e-30 102.6 30.5 4.3e-08 33.7 1.6 8.6 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD31725.1 - 1.9e-09 37.7 1.9 0.17 12.2 0.1 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 PVD31725.1 - 1.8e-07 30.9 0.1 4.9e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif IKI3 PF04762.12 PVD31725.1 - 0.071 11.1 0.5 0.18 9.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family PMP22_Claudin PF00822.20 PVD31726.1 - 1.4e-13 51.1 13.2 2.2e-13 50.4 13.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD31726.1 - 1.2e-07 31.7 8.6 1.2e-07 31.7 8.6 2.9 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD31726.1 - 2.2e-05 24.5 10.2 3.1e-05 24.0 10.2 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Atthog PF18800.1 PVD31726.1 - 0.003 17.5 5.5 0.003 17.5 5.5 1.8 2 0 0 2 2 2 1 Attenuator of Hedgehog RSN1_TM PF13967.6 PVD31726.1 - 0.075 12.8 0.3 0.075 12.8 0.3 2.5 2 2 0 2 2 2 0 Late exocytosis, associated with Golgi transport Polysacc_synt PF01943.17 PVD31726.1 - 0.084 12.2 6.3 0.19 11.1 4.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TMEM223 PF14640.6 PVD31726.1 - 0.094 12.9 1.3 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 DUF2304 PF10066.9 PVD31726.1 - 0.34 11.2 8.5 0.45 10.8 2.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) WSS_VP PF12175.8 PVD31726.1 - 2.4 7.6 3.7 0.94 8.9 0.1 1.9 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP Sema PF01403.19 PVD31727.1 - 0.027 13.3 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Sema domain Protocadherin PF08374.11 PVD31727.1 - 0.086 12.8 0.1 8.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Protocadherin Diphthamide_syn PF01866.17 PVD31728.1 - 5.3e-113 377.5 0.0 6.8e-113 377.1 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SRR1 PF07985.12 PVD31728.1 - 1.9e-11 43.8 0.0 6.2e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 SRR1 Pkinase PF00069.25 PVD31729.1 - 8.2e-78 261.4 0.0 9.9e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31729.1 - 3.1e-32 111.9 0.0 4.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD31729.1 - 1.6e-09 37.5 0.0 4.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD31729.1 - 1.9e-05 24.7 0.0 9e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD31729.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD31729.1 - 0.00089 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 PVD31729.1 - 0.0059 15.5 0.1 0.0086 15.0 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 PVD31729.1 - 0.022 14.4 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 PVD31729.1 - 0.025 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PVD31729.1 - 0.058 13.0 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 PVD31729.1 - 0.093 12.2 0.2 0.22 11.0 0.1 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL VWA PF00092.28 PVD31730.1 - 2.6e-70 236.2 2.6 7.1e-36 124.1 0.1 2.0 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD31730.1 - 2.1e-27 95.9 0.2 8.3e-15 55.4 0.2 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD31730.1 - 1.9e-10 40.9 0.1 6.9e-05 22.8 0.0 2.5 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF1194 PF06707.11 PVD31730.1 - 4.6e-06 26.0 0.5 0.0089 15.3 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) Copine PF07002.16 PVD31730.1 - 0.00081 18.9 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 Copine IF3_N PF05198.16 PVD31730.1 - 0.11 12.8 0.1 13 6.1 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain zf-dskA_traR PF01258.17 PVD31730.1 - 0.47 10.4 0.1 0.47 10.4 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Death PF00531.22 PVD31734.1 - 0.017 15.2 0.5 0.19 11.9 0.1 2.9 2 0 0 2 2 2 0 Death domain Uso1_p115_C PF04871.13 PVD31734.1 - 1.8 9.0 17.9 3.4 8.1 6.6 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4200 PF13863.6 PVD31734.1 - 6.7 7.1 22.8 2.1 8.8 12.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 PVD31734.1 - 8.3 6.7 10.2 16 5.8 0.6 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 PVD31736.1 - 7e-22 77.3 6.4 1.5e-21 76.2 6.4 1.6 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF3161 PF11362.8 PVD31736.1 - 3.7e-14 52.5 0.2 6.3e-13 48.5 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 PVD31736.1 - 0.0025 17.7 4.7 0.028 14.3 4.7 2.2 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4659 PF15558.6 PVD31736.1 - 0.047 12.6 6.6 0.087 11.7 6.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4659) zf-RING_2 PF13639.6 PVD31737.1 - 1.8e-12 47.4 8.0 1.8e-12 47.4 8.0 2.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 PVD31737.1 - 1.7e-10 40.4 4.2 4.5e-10 39.1 3.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD31737.1 - 2.1e-08 33.9 8.0 6.3e-08 32.3 8.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD31737.1 - 7.6e-08 32.1 6.8 2.1e-07 30.7 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD31737.1 - 8.7e-07 29.1 10.8 1.8e-05 25.0 10.8 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PVD31737.1 - 1.8e-06 27.7 3.9 4.9e-06 26.3 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD31737.1 - 2.8e-06 27.2 5.4 7e-06 25.9 5.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD31737.1 - 4.2e-05 23.5 5.9 0.00011 22.1 5.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD31737.1 - 0.00024 20.9 5.5 0.00063 19.6 5.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ZNRF_3_ecto PF18212.1 PVD31737.1 - 0.00075 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-C3H2C3 PF17122.5 PVD31737.1 - 0.0078 16.2 3.4 0.028 14.5 3.4 2.0 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 PVD31737.1 - 0.17 12.0 7.3 0.42 10.7 6.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PVD31737.1 - 1.8 8.8 7.6 2 8.6 5.5 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain MMR_HSR1 PF01926.23 PVD31738.1 - 8.3e-22 77.4 0.1 1.7e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD31738.1 - 5.8e-12 45.4 0.3 1.3e-11 44.2 0.3 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD31738.1 - 4.5e-09 36.1 0.0 3.2e-06 26.8 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PVD31738.1 - 4.4e-06 26.2 0.1 7.9e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 PVD31738.1 - 1.6e-05 25.1 2.8 0.011 15.8 0.2 2.7 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD31738.1 - 1.6e-05 24.9 1.0 0.0076 16.2 0.2 2.6 3 0 0 3 3 3 2 RsgA GTPase GBP PF02263.19 PVD31738.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Arf PF00025.21 PVD31738.1 - 0.0017 17.8 0.2 0.049 13.1 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family G-alpha PF00503.20 PVD31738.1 - 0.0023 17.1 0.6 0.24 10.5 0.3 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 PVD31738.1 - 0.0024 18.1 0.2 0.0095 16.2 0.2 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD31738.1 - 0.0026 17.4 0.1 0.012 15.3 0.1 1.9 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 PVD31738.1 - 0.004 16.6 0.3 0.0092 15.4 0.3 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PVD31738.1 - 0.008 15.9 0.0 1.8 8.3 0.0 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 PVD31738.1 - 0.013 15.3 0.2 1.4 8.6 0.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PVD31738.1 - 0.015 15.9 0.0 0.38 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD31738.1 - 0.02 15.3 0.1 0.044 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 PVD31738.1 - 0.024 13.7 0.0 0.45 9.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NOG1 PF06858.14 PVD31738.1 - 0.38 10.6 1.7 3.7 7.4 0.2 2.6 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Peptidase_A22B PF04258.13 PVD31739.1 - 4.8e-90 301.9 16.8 6.5e-90 301.5 16.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Ras PF00071.22 PVD31740.1 - 7.2e-49 165.5 0.0 8.3e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31740.1 - 1.3e-22 80.2 0.0 1.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31740.1 - 2.7e-06 27.0 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD31740.1 - 0.0045 16.4 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD31740.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 PVD31740.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CLU PF13236.6 PVD31741.1 - 2.6e-88 295.6 0.0 4.7e-88 294.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PVD31741.1 - 5.3e-53 179.7 0.7 1.7e-52 178.0 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PVD31741.1 - 5.2e-24 84.3 8.9 1.8e-12 47.4 1.7 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD31741.1 - 5.5e-15 54.7 13.4 7.1e-07 28.9 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 PVD31741.1 - 1.3e-13 51.0 1.2 3.1e-13 49.9 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_MalT PF17874.1 PVD31741.1 - 1.7e-06 27.7 2.2 9.5e-06 25.2 2.2 1.9 1 1 0 1 1 1 1 MalT-like TPR region DUF727 PF05303.12 PVD31741.1 - 1e-05 25.5 0.1 8.4e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 PVD31741.1 - 0.083 12.8 0.2 2.8 7.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31741.1 - 0.12 12.6 6.7 1.7 9.0 0.1 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Fer4 PF00037.27 PVD31742.1 - 4.7e-14 51.5 17.5 1.8e-08 33.9 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 PVD31742.1 - 1.1e-12 48.4 10.1 2.2e-12 47.4 10.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 PVD31742.1 - 1.5e-10 41.9 7.1 3.1e-05 24.8 0.1 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 PVD31742.1 - 1.8e-09 37.6 5.4 0.00019 21.5 0.4 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 PVD31742.1 - 6.3e-09 36.2 2.0 0.00023 21.5 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 PVD31742.1 - 1.1e-08 35.0 10.0 2.2e-08 34.1 10.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PVD31742.1 - 1.9e-08 34.3 21.0 6.2e-06 26.2 12.4 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PVD31742.1 - 3e-07 30.2 17.8 0.0004 20.3 5.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 PVD31742.1 - 1.2e-06 28.2 12.1 0.0028 17.7 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 PVD31742.1 - 5.7e-06 26.4 11.1 0.00035 20.8 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 PVD31742.1 - 0.00038 20.9 11.3 0.047 14.2 12.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 PVD31742.1 - 0.0083 16.3 5.6 0.59 10.4 0.3 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 PVD31742.1 - 0.017 15.6 14.7 0.72 10.4 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 PVD31742.1 - 0.043 14.0 8.6 1.1 9.5 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 PVD31742.1 - 0.18 12.8 16.3 0.35 11.9 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 PVD31742.1 - 0.34 11.1 5.8 1.4 9.1 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 PVD31742.1 - 0.98 10.3 11.9 3.2 8.6 2.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain MMR_HSR1_Xtn PF16897.5 PVD31743.1 - 8.7e-43 144.7 0.9 8.7e-43 144.7 0.9 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 PVD31743.1 - 2.8e-25 88.1 0.1 6.6e-25 86.9 0.0 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 PVD31743.1 - 3.9e-19 68.8 0.0 8.8e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD31743.1 - 4.9e-10 39.2 0.0 2.4e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PVD31743.1 - 0.008 16.3 0.3 4.1 7.4 0.2 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 PVD31743.1 - 0.014 14.4 0.0 0.032 13.2 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 PVD31743.1 - 0.04 13.5 0.0 8.8 5.8 0.0 3.4 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain EIF4E-T PF10477.9 PVD31744.1 - 3.6e-58 197.9 64.3 3.6e-58 197.9 64.3 3.6 2 1 0 2 2 2 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1619 PF07773.11 PVD31745.1 - 6.1e-50 170.9 18.7 1.3e-48 166.6 14.4 3.8 3 2 0 4 4 4 2 Protein of unknown function (DUF1619) Med3 PF11593.8 PVD31745.1 - 4.1 6.5 15.4 5 6.2 0.6 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CAF1 PF04857.20 PVD31746.1 - 1.4e-33 116.5 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 PVD31746.1 - 0.00089 19.2 1.0 0.0012 18.8 0.1 1.7 2 0 0 2 2 2 1 RNA binding domain SAM_2 PF07647.17 PVD31747.1 - 1.4e-27 95.6 0.1 2.9e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD31747.1 - 1.7e-20 73.2 0.1 9.7e-13 48.4 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 PVD31747.1 - 6.6e-09 36.4 0.0 1.7e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 TIR domain HEAT_2 PF13646.6 PVD31747.1 - 0.078 13.4 0.1 25 5.3 0.0 3.3 2 1 1 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 PVD31747.1 - 0.08 13.5 0.1 2 9.0 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 PVD31747.1 - 0.25 11.5 1.9 1.8 8.7 0.4 3.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ADAM_CR_2 PF17771.1 PVD31748.1 - 1.3e-15 57.6 1.9 3.7e-15 56.2 1.9 1.8 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin PF01421.19 PVD31748.1 - 1.3e-13 51.3 0.0 2.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD31748.1 - 4.4e-10 40.0 0.0 1.2e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD31748.1 - 7.5e-07 29.7 0.4 2.2e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD31748.1 - 0.00012 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD31748.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NIBRIN_BRCT_II PF16508.5 PVD31749.1 - 2.5e-18 66.5 0.0 6.2e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein Nbs1_C PF08599.10 PVD31749.1 - 1.5e-15 57.0 0.1 3.7e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 FHA PF00498.26 PVD31749.1 - 2.5e-15 56.6 0.2 6.1e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD31749.1 - 6.6e-05 23.2 0.0 0.00041 20.6 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 PVD31749.1 - 0.00015 21.6 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 PVD31749.1 - 0.0012 19.2 0.2 0.014 15.8 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Crystall_4 PF17945.1 PVD31749.1 - 0.0038 17.7 0.1 3 8.3 0.0 2.8 2 0 0 2 2 2 2 Beta/Gamma crystallin IF-2B PF01008.17 PVD31750.1 - 9.8e-70 234.9 0.1 1.6e-69 234.3 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 PVD31750.1 - 0.79 8.3 12.0 1.3 7.7 12.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4719 PF15843.5 PVD31750.1 - 1.6 8.8 6.2 3.9 7.5 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SNX17_FERM_C PF18116.1 PVD31751.1 - 1.4e-37 128.0 0.2 3.4e-37 126.7 0.0 1.7 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain FERM_N PF09379.10 PVD31751.1 - 0.0046 16.9 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 PVD31751.1 - 0.048 14.1 2.1 0.9 10.0 0.9 2.4 1 1 1 2 2 2 0 FERM central domain Ras_bdg_2 PF14847.6 PVD31751.1 - 0.06 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Hfq PF17209.3 PVD31751.1 - 0.11 12.2 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Hfq protein ADK PF00406.22 PVD31752.1 - 8.9e-60 201.2 0.0 1.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PVD31752.1 - 1.9e-24 86.6 0.0 4.8e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PVD31752.1 - 2.2e-16 59.5 0.0 5.6e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PVD31752.1 - 0.00014 22.0 0.0 0.00098 19.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 PVD31752.1 - 0.0021 17.8 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 PVD31752.1 - 0.0046 17.5 0.0 0.015 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 PVD31752.1 - 0.028 14.7 0.1 0.1 12.9 0.0 1.9 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA PF00004.29 PVD31752.1 - 0.082 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Tmemb_cc2 PF10267.9 PVD31752.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Thymidylate_kin PF02223.17 PVD31752.1 - 0.16 11.6 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Sulfotransfer_2 PF03567.14 PVD31753.1 - 2.1e-27 96.7 3.0 6.2e-23 82.0 0.1 2.9 3 0 0 3 3 3 2 Sulfotransferase family MFS_1 PF07690.16 PVD31754.1 - 1.1e-38 133.1 63.1 1.4e-31 109.8 56.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 PVD31754.1 - 4e-06 25.9 30.1 1.5e-05 24.1 30.1 1.9 1 1 0 1 1 1 1 MFS_1 like family Trypsin PF00089.26 PVD31755.1 - 1.1e-60 205.2 0.1 2.5e-60 204.0 0.1 1.7 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 PVD31755.1 - 1.1e-56 188.7 130.6 1.1e-10 41.5 12.5 9.2 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A MAM PF00629.23 PVD31755.1 - 3.2e-50 170.2 4.2 1.6e-25 89.9 0.0 3.8 4 0 0 4 4 4 3 MAM domain, meprin/A5/mu Fz PF01392.22 PVD31755.1 - 3.7e-32 111.2 31.9 1.4e-12 48.2 1.8 5.5 5 1 0 5 5 5 3 Fz domain DUF1986 PF09342.11 PVD31755.1 - 3.7e-07 30.5 0.0 8.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) SPX PF03105.19 PVD31755.1 - 3.2 7.6 7.4 5.5 6.8 7.4 1.3 1 0 0 1 1 1 0 SPX domain 7tm_1 PF00001.21 PVD31759.1 - 1e-20 74.2 0.1 1.3e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 PVD31760.1 - 7.7e-20 71.1 49.1 3.9e-18 65.5 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_7 PF13499.6 PVD31761.1 - 3e-11 43.6 0.1 1.9e-06 28.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD31761.1 - 2.8e-10 39.0 3.5 0.00027 20.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD31761.1 - 8.7e-10 37.7 2.2 0.00021 21.0 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PVD31761.1 - 2.3e-07 30.6 1.2 0.1 12.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD31761.1 - 1.1e-06 27.8 2.5 0.14 11.7 0.0 3.3 3 0 0 3 3 3 3 EF hand Daxx PF03344.15 PVD31761.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain SPARC_Ca_bdg PF10591.9 PVD31761.1 - 0.065 13.6 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Patched PF02460.18 PVD31762.1 - 1.7e-87 294.4 25.4 2.8e-58 197.8 2.4 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 PVD31762.1 - 8e-57 191.4 4.4 8e-57 191.4 4.4 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 PVD31762.1 - 8.2e-50 169.6 6.4 2.8e-34 118.8 0.7 2.4 1 1 1 2 2 2 2 Niemann-Pick C1 N terminus MMPL PF03176.15 PVD31762.1 - 0.00043 19.3 4.8 0.00043 19.3 4.8 2.8 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.19 PVD31762.1 - 0.029 12.0 8.8 0.054 11.2 8.8 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3034 PF11231.8 PVD31762.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) BK_channel_a PF03493.18 PVD31764.1 - 5e-26 90.8 0.1 1.1e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PVD31764.1 - 2.3e-12 46.7 3.9 2.3e-12 46.7 3.9 2.1 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 PVD31764.1 - 0.11 12.8 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Ion_trans PF00520.31 PVD31764.1 - 0.18 11.0 18.7 0.028 13.6 13.5 2.0 2 0 0 2 2 2 0 Ion transport protein Ras PF00071.22 PVD31765.1 - 7.3e-42 142.7 0.2 9.2e-42 142.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31765.1 - 1.7e-27 96.0 0.1 2.5e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31765.1 - 3.9e-11 42.7 0.1 4.8e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD31765.1 - 9.5e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD31765.1 - 0.00042 19.9 0.4 0.014 15.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DLIC PF05783.11 PVD31765.1 - 0.00074 18.5 0.5 0.074 11.9 0.2 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) ATP_bind_1 PF03029.17 PVD31765.1 - 0.0016 18.3 0.0 0.59 9.9 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PVD31765.1 - 0.0019 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD31765.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 PVD31765.1 - 0.0045 17.1 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PVD31765.1 - 0.024 14.4 0.1 0.21 11.3 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 PVD31765.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 PVD31765.1 - 0.035 13.5 0.0 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 PVD31765.1 - 0.038 13.7 0.1 0.078 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 PVD31765.1 - 0.046 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1_Xtn PF16897.5 PVD31765.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Sigma54_activat PF00158.26 PVD31765.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 PVD31765.1 - 0.099 11.8 0.1 3.8 6.6 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 PVD31765.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_32 PF13654.6 PVD31765.1 - 0.15 10.8 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain Archease PF01951.16 PVD31766.1 - 4e-24 85.4 0.0 5.7e-24 84.9 0.0 1.3 1 1 0 1 1 1 1 Archease protein family (MTH1598/TM1083) IQ PF00612.27 PVD31767.1 - 0.051 13.4 0.7 0.12 12.2 0.7 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Aminotran_5 PF00266.19 PVD31768.1 - 1.1e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AlbA_2 PF04326.14 PVD31769.1 - 1.3e-22 80.4 0.0 2.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain Cep57_CLD PF14073.6 PVD31769.1 - 0.01 15.9 1.5 0.014 15.4 1.5 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Reprolysin PF01421.19 PVD31770.1 - 5.3e-11 42.8 0.0 9.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD31770.1 - 2.1e-10 41.1 0.0 2.1e-10 41.1 0.0 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 PVD31770.1 - 2.5e-08 34.3 7.3 2.5e-08 34.3 7.3 2.5 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 PVD31770.1 - 1e-06 29.3 0.1 3.5e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD31770.1 - 2.3e-05 24.4 0.5 9.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD31770.1 - 0.00026 20.7 0.0 0.00093 18.9 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DAP3 PF10236.9 PVD31771.1 - 0.0089 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Phage_ASH PF10554.9 PVD31772.1 - 0.071 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Ash protein family HNF_C PF09354.10 PVD31773.1 - 0.054 14.5 1.8 0.16 13.1 0.4 2.4 1 1 1 2 2 2 0 HNF3 C-terminal domain FAM167 PF11652.8 PVD31774.1 - 1.1e-28 99.6 1.8 2.1e-28 98.6 1.8 1.5 1 0 0 1 1 1 1 FAM167 LURAP PF14854.6 PVD31774.1 - 0.001 19.0 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Leucine rich adaptor protein CCDC154 PF15450.6 PVD31774.1 - 0.024 13.2 1.4 0.032 12.8 1.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 DUF4404 PF14357.6 PVD31774.1 - 0.047 14.3 3.7 0.4 11.4 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) OATP PF03137.20 PVD31775.1 - 4.7e-141 470.8 21.1 6e-141 470.4 21.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD31775.1 - 7.6e-19 67.8 44.4 2.1e-16 59.8 14.5 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD31775.1 - 4e-07 30.0 12.9 9e-07 28.9 12.9 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ATG22 PF11700.8 PVD31775.1 - 0.00038 19.2 2.9 0.00076 18.2 2.9 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Kazal_1 PF00050.21 PVD31775.1 - 0.032 14.2 6.4 0.086 12.9 6.4 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 PVD31776.1 - 2e-19 67.6 5.8 5.6e-08 31.8 0.4 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PVD31776.1 - 7.9e-17 61.5 3.3 5e-15 55.7 1.3 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD31776.1 - 4.2e-15 54.3 0.6 3.1e-06 26.7 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PVD31776.1 - 1.1e-12 47.6 3.9 2.6e-10 40.0 0.4 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD31776.1 - 9.8e-10 37.5 4.2 0.00091 18.6 0.1 3.3 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD31776.1 - 2.8e-05 24.4 0.2 3.4e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD31776.1 - 5.1e-05 23.4 0.2 7.3e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_4 PF12763.7 PVD31776.1 - 0.00011 22.1 1.0 0.00083 19.3 0.3 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF4259 PF14078.6 PVD31776.1 - 0.018 15.8 0.7 0.052 14.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) EF-hand_10 PF14788.6 PVD31776.1 - 0.07 13.0 3.2 3.4 7.6 0.0 2.7 1 1 1 3 3 3 0 EF hand DHHC PF01529.20 PVD31777.1 - 5.9e-25 87.9 9.5 5.9e-25 87.9 9.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_transf_11 PF01531.16 PVD31779.1 - 1.7e-26 93.2 0.3 2.5e-26 92.6 0.2 1.3 2 0 0 2 2 2 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD31779.1 - 4.3e-09 36.5 0.0 8.8e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD31780.1 - 1.2e-30 106.7 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD31780.1 - 0.0003 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD31781.1 - 7.8e-13 48.3 0.0 8.5e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD31782.1 - 0.089 12.5 3.4 0.74 9.5 3.8 1.9 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD31783.1 - 9.8e-13 48.0 0.0 1.1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Cadherin PF00028.17 PVD31784.1 - 5.2e-28 97.3 11.4 3.1e-08 34.0 0.5 6.4 5 1 0 6 6 6 4 Cadherin domain Cadherin_3 PF16184.5 PVD31784.1 - 6.2e-07 29.4 7.7 0.079 13.0 0.0 5.7 5 1 1 6 6 6 2 Cadherin-like Oxidored_q3 PF00499.20 PVD31784.1 - 0.081 12.6 1.5 0.76 9.5 0.6 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Renin_r PF07850.14 PVD31784.1 - 0.24 12.0 2.7 1.2 9.8 0.0 2.9 3 0 0 3 3 3 0 Renin receptor-like protein TMEM154 PF15102.6 PVD31784.1 - 0.27 11.2 2.8 1.3 8.9 1.1 2.7 2 0 0 2 2 2 0 TMEM154 protein family Hum_adeno_E3A PF05393.11 PVD31784.1 - 0.44 10.6 5.9 0.95 9.5 0.1 2.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Filamin PF00630.19 PVD31785.1 - 0.1 13.4 0.2 0.48 11.3 0.0 2.1 2 1 0 2 2 2 0 Filamin/ABP280 repeat Glycoprotein PF03409.15 PVD31786.1 - 0.14 10.9 2.2 0.19 10.6 2.2 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein SSP160 PF06933.11 PVD31786.1 - 0.25 9.5 4.3 0.3 9.3 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mito_fiss_reg PF05308.11 PVD31786.1 - 1.1 9.3 5.4 1.6 8.7 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cadherin PF00028.17 PVD31787.1 - 1.5e-08 34.9 2.4 0.00038 20.9 0.2 3.8 3 1 0 3 3 3 2 Cadherin domain Clostridium_P47 PF06597.11 PVD31787.1 - 0.022 13.5 0.5 0.052 12.3 0.5 1.6 1 1 1 2 2 2 0 Clostridium P-47 protein Cadherin PF00028.17 PVD31789.1 - 7.2e-16 58.4 8.0 1.2e-05 25.7 0.1 5.6 4 1 1 5 5 5 5 Cadherin domain Invasin_D3 PF09134.10 PVD31789.1 - 0.42 11.0 10.9 0.082 13.2 3.4 3.1 2 1 1 3 3 3 0 Invasin, domain 3 Cadherin PF00028.17 PVD31790.1 - 5e-14 52.5 5.7 5e-06 26.9 0.2 3.1 3 0 0 3 3 3 2 Cadherin domain Apolipo_F PF15148.6 PVD31790.1 - 0.1 12.0 0.1 0.43 10.1 0.0 2.0 1 1 1 2 2 2 0 Apolipoprotein F BACON PF13004.7 PVD31790.1 - 1.4 9.0 13.6 0.2 11.6 0.7 3.8 2 2 1 3 3 3 0 Putative binding domain, N-terminal Cadherin PF00028.17 PVD31791.1 - 9.9e-08 32.3 0.2 3.9e-05 24.0 0.0 2.9 2 1 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 PVD31792.1 - 4.9e-07 30.1 3.1 4.6e-06 27.0 0.2 3.3 3 1 1 4 4 4 1 Cadherin domain Prominin PF05478.11 PVD31792.1 - 1.9 6.4 3.5 2.7 5.9 3.5 1.1 1 0 0 1 1 1 0 Prominin Protocadherin PF08374.11 PVD31793.1 - 0.001 19.1 1.1 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 Protocadherin EphA2_TM PF14575.6 PVD31793.1 - 0.0012 19.6 0.0 0.0048 17.7 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD31793.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 PVD31793.1 - 0.077 12.8 0.4 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 PVD31793.1 - 0.088 12.2 5.2 0.19 11.2 5.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Stevor PF17410.2 PVD31793.1 - 0.1 12.1 0.4 0.31 10.5 0.0 2.0 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame VSP PF03302.13 PVD31793.1 - 0.13 11.0 4.4 0.2 10.5 4.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Myb_DNA-bind_4 PF13837.6 PVD31794.1 - 7.9e-08 32.6 0.1 1.6e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD31794.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 PVD31794.1 - 0.022 15.0 0.6 0.044 14.0 0.6 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Corona_S2 PF01601.16 PVD31794.1 - 0.076 11.5 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Myb_DNA-bind_3 PF12776.7 PVD31794.1 - 0.095 13.7 0.1 0.21 12.6 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain YTH PF04146.15 PVD31796.1 - 1.4e-46 158.5 0.1 3.1e-46 157.4 0.1 1.6 1 0 0 1 1 1 1 YT521-B-like domain AAA_13 PF13166.6 PVD31797.1 - 0.0021 16.8 1.1 0.0028 16.4 1.1 1.1 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.9 PVD31797.1 - 0.0033 17.7 8.8 0.13 12.6 1.1 3.4 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_C PF00059.21 PVD31797.1 - 0.0054 17.4 4.4 0.073 13.8 0.0 2.6 2 1 0 2 2 2 1 Lectin C-type domain NPV_P10 PF05531.12 PVD31797.1 - 0.014 15.8 8.6 0.053 14.0 3.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 PVD31797.1 - 0.026 14.9 4.3 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF735 PF05246.11 PVD31797.1 - 0.03 14.3 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF735) SlyX PF04102.12 PVD31797.1 - 0.15 12.7 0.4 0.15 12.7 0.4 2.7 3 1 1 4 4 3 0 SlyX DASH_Dam1 PF08653.10 PVD31797.1 - 0.16 11.8 3.4 20 5.1 0.0 3.4 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF1863 PF08937.11 PVD31797.1 - 0.19 12.0 3.2 0.31 11.4 3.2 1.3 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF1366 PF07104.11 PVD31797.1 - 0.36 10.5 2.7 0.32 10.7 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) FapA PF03961.13 PVD31797.1 - 0.59 8.7 3.2 0.77 8.3 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_HK97_TLTM PF06120.11 PVD31797.1 - 0.7 9.0 5.9 1 8.5 5.9 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF16 PF01519.16 PVD31797.1 - 0.73 10.3 6.9 1.8 9.1 4.5 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Uso1_p115_C PF04871.13 PVD31797.1 - 1 9.7 5.8 1.4 9.3 4.0 1.9 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 PVD31797.1 - 1.1 9.3 7.7 18 5.4 5.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 PVD31797.1 - 1.1 9.1 6.7 1.9 8.3 0.8 2.3 1 1 1 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 PVD31797.1 - 4.3 7.5 8.6 27 4.9 8.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 PVD31798.1 - 0.0044 17.1 0.9 0.0044 17.1 0.9 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus PLU-1 PF08429.11 PVD31798.1 - 0.099 11.8 2.0 0.079 12.1 0.6 1.4 2 0 0 2 2 2 0 PLU-1-like protein Lectin_C PF00059.21 PVD31799.1 - 6.1e-16 59.1 0.3 1.6e-15 57.8 0.0 1.8 2 1 1 3 3 3 1 Lectin C-type domain DIRP PF06584.13 PVD31799.1 - 0.01 16.0 0.1 0.025 14.7 0.0 1.6 2 0 0 2 2 2 0 DIRP Apolipoprotein PF01442.18 PVD31799.1 - 0.025 14.4 6.7 0.038 13.9 6.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD31799.1 - 0.082 12.9 8.9 0.23 11.5 8.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 PVD31799.1 - 0.087 11.7 4.5 0.12 11.3 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 PVD31799.1 - 0.18 12.6 3.1 4.7 8.0 1.3 2.2 1 1 1 2 2 2 0 Occludin homology domain Phasin PF05597.11 PVD31799.1 - 0.19 11.7 3.2 0.31 11.0 3.2 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Csd3_N PF18059.1 PVD31799.1 - 0.2 12.2 2.1 11 6.7 0.3 2.5 1 1 1 2 2 2 0 Csd3 N-terminal DUF4407 PF14362.6 PVD31799.1 - 0.2 11.0 3.3 0.29 10.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD31799.1 - 0.63 9.6 6.6 0.76 9.3 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 PVD31799.1 - 1 9.9 4.1 4.6 7.8 4.1 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lectin_C PF00059.21 PVD31800.1 - 3.6e-09 37.3 0.0 1.2e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Lectin C-type domain Baculo_PEP_C PF04513.12 PVD31800.1 - 0.0042 17.1 36.4 0.21 11.6 3.5 4.2 2 2 2 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 PVD31800.1 - 0.027 14.5 17.7 0.19 11.7 1.2 3.9 2 2 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AUX_IAA PF02309.16 PVD31800.1 - 0.063 13.1 0.4 5.1 6.9 0.0 2.6 2 1 0 2 2 2 0 AUX/IAA family Collagen_mid PF15984.5 PVD31800.1 - 0.39 10.5 7.2 5.2 6.8 1.4 2.8 2 1 0 2 2 2 0 Bacterial collagen, middle region ING PF12998.7 PVD31800.1 - 0.45 11.1 20.0 0.47 11.1 0.1 4.5 3 2 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding FAM184 PF15665.5 PVD31800.1 - 0.58 9.9 27.0 0.55 10.0 2.5 2.6 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3584 PF12128.8 PVD31800.1 - 3.9 4.9 25.1 0.52 7.8 11.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF1043 PF06295.12 PVD31800.1 - 8.8 6.3 16.9 2.9 7.9 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Lectin_C PF00059.21 PVD31801.1 - 3e-13 50.4 0.0 7.9e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 Lectin C-type domain PAN_2 PF08276.11 PVD31801.1 - 6.7e-06 26.1 0.8 0.14 12.3 0.1 2.5 2 0 0 2 2 2 2 PAN-like domain ASTN_2_hairpin PF18577.1 PVD31801.1 - 0.12 12.6 0.3 0.36 11.0 0.3 1.8 1 0 0 1 1 1 0 Astrotactin-2 C-terminal beta-hairpin domain PAN_4 PF14295.6 PVD31801.1 - 0.14 12.1 3.9 4.3 7.3 0.2 2.8 2 0 0 2 2 2 0 PAN domain PAN_3 PF08277.12 PVD31801.1 - 0.44 10.4 7.6 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 PAN-like domain Glutaminase PF04960.15 PVD31802.1 - 2.6e-78 263.1 0.1 1.2e-44 152.6 0.0 3.3 1 1 1 2 2 2 2 Glutaminase EF-hand_14 PF17959.1 PVD31802.1 - 1.3e-21 76.7 0.0 2.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain Ank_4 PF13637.6 PVD31802.1 - 5.5e-12 46.0 0.1 2.8e-06 27.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD31802.1 - 1.8e-10 41.2 0.0 5.1e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD31802.1 - 4.6e-08 33.2 0.1 6.5e-07 29.5 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD31802.1 - 2.7e-06 27.6 0.0 9.6e-05 22.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 PVD31802.1 - 0.00054 20.2 0.0 0.0024 18.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat TPR_14 PF13428.6 PVD31803.1 - 0.0051 17.5 0.3 1.6 9.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31803.1 - 0.02 15.0 1.5 7.5 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31803.1 - 0.048 13.9 0.4 4.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31803.1 - 0.08 13.5 0.0 18 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD31803.1 - 0.096 12.9 0.1 6.5 7.1 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CSTF1_dimer PF16699.5 PVD31803.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain TPR_1 PF00515.28 PVD31803.1 - 0.14 12.0 3.4 1.1 9.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 PVD31804.1 - 1.2e-115 387.0 0.6 1.6e-115 386.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_1 PF00515.28 PVD31804.1 - 3.5e-06 26.6 2.6 0.04 13.8 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD31804.1 - 4.3e-06 26.9 2.3 0.028 14.7 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31804.1 - 7.9e-06 25.6 6.3 0.41 10.9 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD31804.1 - 2.4e-05 24.2 2.0 0.011 15.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD31804.1 - 0.0028 16.9 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD31804.1 - 0.003 17.5 3.2 1.7 8.8 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Cohesin_load PF10345.9 PVD31804.1 - 0.0031 16.0 4.0 0.018 13.5 0.1 2.7 3 0 0 3 3 3 1 Cohesin loading factor ANAPC3 PF12895.7 PVD31804.1 - 0.0037 17.5 2.9 1.8 8.8 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD31804.1 - 0.0053 17.5 0.5 1.5 9.8 0.1 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD31804.1 - 0.0069 17.0 4.0 21 6.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Muted PF14942.6 PVD31805.1 - 2.1e-31 109.2 5.0 2.5e-31 109.0 5.0 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Snurportin1 PF11538.8 PVD31805.1 - 0.014 15.6 2.0 0.036 14.3 2.0 1.7 1 0 0 1 1 1 0 Snurportin1 DUF5078 PF16877.5 PVD31805.1 - 0.25 11.8 2.7 1.4 9.4 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5078) PMP22_Claudin PF00822.20 PVD31807.1 - 5.5e-11 42.6 6.3 7.9e-11 42.1 5.0 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD31807.1 - 6.6e-07 29.3 17.1 1.7e-05 24.7 17.1 2.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD31807.1 - 4.1e-05 23.9 5.1 0.00017 21.8 5.1 1.9 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein MARVEL PF01284.23 PVD31807.1 - 0.0041 17.2 10.8 0.021 14.8 10.9 2.1 1 1 0 1 1 1 1 Membrane-associating domain 7TM-7TMR_HD PF07698.11 PVD31807.1 - 0.051 13.3 4.9 0.074 12.8 4.9 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DuoxA PF10204.9 PVD31807.1 - 0.092 11.7 2.8 0.12 11.3 2.8 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF423 PF04241.15 PVD31807.1 - 0.095 12.9 4.3 11 6.3 4.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF423) MFS_1 PF07690.16 PVD31807.1 - 0.23 10.3 12.8 0.017 14.1 8.0 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF2700 PF10912.8 PVD31807.1 - 0.26 11.3 4.3 0.86 9.6 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2700) DUF4064 PF13273.6 PVD31807.1 - 0.68 10.2 20.5 0.53 10.6 7.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 PVD31808.1 - 2.1e-05 24.4 0.1 2.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD31808.1 - 0.0062 16.4 0.1 0.0078 16.1 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Gp37 PF09646.10 PVD31808.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Gp37 protein ANF_receptor PF01094.28 PVD31809.1 - 1.4e-49 169.1 2.1 2e-49 168.6 2.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD31809.1 - 2.4e-46 158.4 19.6 4.3e-46 157.6 19.6 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Complex1_51K PF01512.17 PVD31809.1 - 1.1e-33 116.3 0.0 2.2e-28 99.0 0.0 2.6 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 PVD31809.1 - 2.8e-30 104.2 1.0 4.4e-30 103.6 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Peripla_BP_6 PF13458.6 PVD31809.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein SLBB PF10531.9 PVD31809.1 - 0.00015 21.5 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 SLBB domain SPAN-X PF07458.12 PVD31809.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome 7tm_1 PF00001.21 PVD31810.1 - 8e-15 54.9 8.5 8e-15 54.9 8.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GTF2I PF02946.14 PVD31810.1 - 4.1e-05 23.6 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 GTF2I-like repeat DUF5504 PF17608.2 PVD31810.1 - 0.051 13.7 1.4 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5504) HMG_box_2 PF09011.10 PVD31810.1 - 0.16 12.6 0.5 0.39 11.4 0.5 1.6 1 1 0 1 1 1 0 HMG-box domain 7tm_1 PF00001.21 PVD31811.1 - 8.7e-06 25.2 0.1 8.7e-06 25.2 0.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD31812.1 - 4e-23 82.1 3.9 5.7e-23 81.6 3.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3325 PF11804.8 PVD31812.1 - 0.041 14.0 0.6 0.041 14.0 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) CrgA PF06781.12 PVD31812.1 - 0.093 12.8 6.3 0.15 12.2 0.5 3.1 3 0 0 3 3 3 0 Cell division protein CrgA DUF2976 PF11190.8 PVD31812.1 - 0.16 11.8 1.9 0.81 9.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Comm PF15957.5 PVD31812.1 - 3.6 8.0 11.6 0.049 14.0 1.1 3.0 3 1 0 3 3 3 0 Commissureless 7tm_1 PF00001.21 PVD31813.1 - 1.1e-11 44.6 5.3 1.3e-11 44.3 5.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Paz_1 PF18349.1 PVD31813.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 PAZ domain DUF2976 PF11190.8 PVD31813.1 - 0.84 9.5 6.0 4.9 7.0 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Sof1 PF04158.14 PVD31815.1 - 1.4e-30 105.4 11.4 3.1e-30 104.3 11.4 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 PVD31815.1 - 6.9e-20 71.0 3.5 0.00062 20.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD31815.1 - 9e-05 22.7 0.0 0.26 11.6 0.1 3.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD31815.1 - 0.00096 19.1 0.0 0.19 11.6 0.0 2.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PS_pyruv_trans PF04230.13 PVD31816.1 - 8.3e-09 35.8 0.5 1e-07 32.2 0.2 2.6 1 1 1 2 2 2 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31816.1 - 3e-06 26.8 6.0 3.9e-06 26.4 6.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family TPT PF03151.16 PVD31817.1 - 3.5e-08 33.2 9.1 4.1e-08 32.9 9.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Gram_pos_anchor PF00746.21 PVD31817.1 - 0.62 10.0 0.0 0.62 10.0 0.0 2.8 4 0 0 4 4 4 0 LPXTG cell wall anchor motif PS_pyruv_trans PF04230.13 PVD31818.1 - 4.9e-23 82.4 0.2 9e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase FAD_binding_9 PF08021.11 PVD31818.1 - 0.17 12.1 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PS_pyruv_trans PF04230.13 PVD31819.1 - 1.7e-21 77.4 0.3 3e-20 73.3 0.3 2.2 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31819.1 - 1.1e-18 67.7 18.7 1.7e-18 67.0 18.7 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31819.1 - 8.3e-05 22.8 3.0 8.3e-05 22.8 3.0 3.0 3 1 0 3 3 3 1 EamA-like transporter family PRA1 PF03208.19 PVD31819.1 - 0.016 14.8 0.2 0.016 14.8 0.2 3.3 2 2 1 3 3 3 0 PRA1 family protein PS_pyruv_trans PF04230.13 PVD31820.1 - 2e-21 77.2 0.5 6.5e-20 72.2 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31820.1 - 2.1e-19 70.0 22.8 3.5e-19 69.3 22.8 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31820.1 - 2.8e-05 24.3 6.5 2.8e-05 24.3 6.5 2.8 3 0 0 3 3 3 1 EamA-like transporter family PS_pyruv_trans PF04230.13 PVD31821.1 - 1.4e-22 80.9 0.3 1.2e-21 77.9 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31821.1 - 5e-18 65.5 20.1 7.6e-18 64.9 20.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31821.1 - 0.00012 22.3 3.4 0.00012 22.3 3.4 3.0 3 1 0 3 3 3 1 EamA-like transporter family PS_pyruv_trans PF04230.13 PVD31822.1 - 2.6e-22 80.1 0.6 4.3e-21 76.1 0.6 2.2 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31822.1 - 5.3e-18 65.4 16.9 1.2e-17 64.3 16.9 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31822.1 - 0.00012 22.2 4.1 0.00012 22.2 4.1 3.1 3 1 0 3 3 3 1 EamA-like transporter family THAP PF05485.12 PVD31822.1 - 0.02 15.8 0.8 0.13 13.2 0.1 2.6 2 1 1 3 3 3 0 THAP domain LBP_C PF17386.2 PVD31822.1 - 0.23 11.4 0.7 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain PS_pyruv_trans PF04230.13 PVD31823.1 - 3.8e-22 79.5 0.5 1.1e-20 74.8 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31823.1 - 4.2e-16 59.2 19.0 7.6e-16 58.3 19.0 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31823.1 - 0.00022 21.4 4.2 0.00022 21.4 4.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family PS_pyruv_trans PF04230.13 PVD31824.1 - 1e-18 68.3 0.2 5.3e-18 65.9 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31824.1 - 2e-13 50.4 22.5 3.2e-13 49.7 22.5 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31824.1 - 0.00016 21.9 1.9 0.00016 21.9 1.9 2.8 2 1 0 2 2 2 1 EamA-like transporter family PS_pyruv_trans PF04230.13 PVD31825.1 - 1e-21 78.2 0.1 5.1e-21 75.8 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31825.1 - 2.4e-13 50.1 23.0 3.8e-13 49.4 23.0 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31825.1 - 3.3e-05 24.1 3.0 3.3e-05 24.1 3.0 2.9 2 1 0 2 2 2 1 EamA-like transporter family GHD PF17834.1 PVD31825.1 - 0.023 14.7 1.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase PS_pyruv_trans PF04230.13 PVD31826.1 - 1.1e-20 74.7 0.1 3e-20 73.3 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31826.1 - 4.5e-14 52.5 22.5 7.2e-14 51.8 22.5 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31826.1 - 5.5e-05 23.4 4.3 5.5e-05 23.4 4.3 2.9 2 0 0 2 2 2 1 EamA-like transporter family GWT1 PF06423.12 PVD31826.1 - 0.02 15.0 1.3 0.02 15.0 1.3 2.5 3 0 0 3 3 3 0 GWT1 TPT PF03151.16 PVD31827.1 - 9.5e-15 54.7 23.6 1.4e-14 54.2 23.6 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PS_pyruv_trans PF04230.13 PVD31827.1 - 5e-06 26.6 0.3 1.3e-05 25.2 0.3 1.7 1 1 1 2 2 2 1 Polysaccharide pyruvyl transferase EamA PF00892.20 PVD31827.1 - 3.1e-05 24.2 5.0 3.1e-05 24.2 5.0 2.7 2 0 0 2 2 2 1 EamA-like transporter family PS_pyruv_trans PF04230.13 PVD31828.1 - 7.3e-21 75.3 0.3 6.6e-20 72.2 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31828.1 - 5.7e-14 52.1 23.6 9.7e-14 51.4 23.6 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31828.1 - 5.4e-07 29.9 2.8 5.4e-07 29.9 2.8 2.7 2 0 0 2 2 2 1 EamA-like transporter family TMIE PF16038.5 PVD31828.1 - 0.11 12.4 0.5 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 TMIE protein PS_pyruv_trans PF04230.13 PVD31830.1 - 4.3e-21 76.1 0.1 3.6e-20 73.0 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase PS_pyruv_trans PF04230.13 PVD31831.1 - 7.5e-21 75.3 0.1 6.3e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase TPT PF03151.16 PVD31831.1 - 2e-12 47.1 11.9 3.2e-12 46.4 11.9 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD31831.1 - 0.013 15.6 3.2 0.013 15.6 3.2 2.8 2 1 0 2 2 2 0 EamA-like transporter family FAM167 PF11652.8 PVD31832.1 - 5.1e-25 87.8 1.8 7.1e-25 87.3 0.8 1.7 2 0 0 2 2 2 1 FAM167 ATG16 PF08614.11 PVD31832.1 - 0.0094 16.2 6.0 0.0094 16.2 6.0 1.9 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) LURAP PF14854.6 PVD31832.1 - 0.026 14.4 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4530 PF15039.6 PVD31832.1 - 0.032 14.4 1.2 0.057 13.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF2388 PF09498.10 PVD31832.1 - 0.049 13.6 1.9 0.05 13.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) EzrA PF06160.12 PVD31832.1 - 0.11 10.6 1.3 0.15 10.2 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 PVD31832.1 - 0.13 12.5 2.8 0.36 11.1 2.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EF-hand_1 PF00036.32 PVD31834.1 - 6.5e-32 106.7 5.0 1.9e-09 36.4 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD31834.1 - 1.1e-28 99.5 1.3 2.4e-14 53.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD31834.1 - 9.5e-24 81.3 3.6 2.6e-09 36.3 0.1 4.4 3 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PVD31834.1 - 2.1e-22 77.5 3.4 6e-09 35.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PVD31834.1 - 3e-22 78.2 7.2 1.1e-09 37.9 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PVD31834.1 - 2e-08 34.4 0.0 0.00051 20.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD31834.1 - 3e-06 27.5 0.4 0.0046 17.3 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 PVD31834.1 - 0.00016 21.7 0.0 0.3 11.0 0.0 2.3 1 1 1 2 2 2 2 Caleosin related protein UPF0154 PF03672.13 PVD31834.1 - 0.00049 20.1 0.2 0.54 10.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 PVD31834.1 - 0.00098 20.0 0.1 0.27 12.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 PVD31834.1 - 0.0031 17.5 1.8 0.33 10.9 0.0 2.9 1 1 2 3 3 3 1 Tellurite resistance protein TerB EF-hand_4 PF12763.7 PVD31834.1 - 0.0063 16.5 0.3 0.12 12.3 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 PVD31834.1 - 0.0084 16.6 0.1 4.9 7.8 0.1 2.8 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF5580 PF17743.1 PVD31834.1 - 0.025 13.2 0.0 1.1 7.7 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Cytochrome_CBB3 PF13442.6 PVD31834.1 - 0.03 14.6 0.1 0.14 12.5 0.0 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF3008 PF11450.8 PVD31834.1 - 0.049 13.8 2.4 1 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) USP7_C2 PF14533.6 PVD31834.1 - 0.056 13.1 0.2 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal EF-hand_14 PF17959.1 PVD31834.1 - 0.071 13.5 0.1 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF3349 PF11829.8 PVD31834.1 - 0.072 13.9 0.1 9.3 7.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 PVD31834.1 - 0.66 10.2 2.8 19 5.6 1.0 3.0 2 2 1 3 3 3 0 Dockerin type I domain DUF3546 PF12066.8 PVD31835.1 - 3.7e-37 126.9 5.7 3.7e-37 126.9 5.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 PVD31835.1 - 2.9e-35 122.4 26.4 2.9e-35 122.4 26.4 4.4 4 1 0 4 4 4 1 Arsenite-resistance protein 2 RRM_1 PF00076.22 PVD31835.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLC12 PF03522.15 PVD31835.1 - 8 5.4 10.7 21 4.0 10.7 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 PVD31835.1 - 8.9 4.3 7.7 15 3.5 7.7 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 7tm_1 PF00001.21 PVD31837.1 - 2.8e-23 82.6 13.0 9.3e-19 67.8 4.9 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Cadherin PF00028.17 PVD31838.1 - 1.9e-21 76.3 7.7 1.4e-05 25.5 0.1 5.7 6 0 0 6 6 6 5 Cadherin domain DUF4625 PF15418.6 PVD31838.1 - 0.016 15.5 0.2 0.33 11.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) DUF2782 PF11191.8 PVD31838.1 - 0.77 10.0 4.4 0.93 9.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) Cadherin_4 PF17803.1 PVD31838.1 - 2.7 8.7 28.2 19 6.0 0.2 6.3 6 1 0 6 6 6 0 Bacterial cadherin-like domain Cadherin PF00028.17 PVD31839.1 - 1.3e-12 47.9 2.8 0.0014 19.1 0.1 3.7 4 0 0 4 4 4 3 Cadherin domain Cadherin_3 PF16184.5 PVD31839.1 - 0.0036 17.3 1.0 1.1 9.3 0.0 3.5 3 0 0 3 3 3 1 Cadherin-like VirE PF05272.11 PVD31839.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DUF2782 PF11191.8 PVD31839.1 - 0.096 12.9 0.1 0.096 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) MFS_1 PF07690.16 PVD31840.1 - 2e-61 207.9 22.7 2e-61 207.9 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD31840.1 - 3.3e-08 32.8 6.9 3.3e-08 32.8 6.9 2.6 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD31841.1 - 2.7e-23 82.5 9.3 3e-21 75.8 5.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M50B PF13398.6 PVD31841.1 - 0.96 9.1 12.4 0.18 11.5 1.0 2.8 2 1 1 3 3 3 0 Peptidase M50B-like MFS_1 PF07690.16 PVD31842.1 - 6.3e-55 186.5 26.6 4.8e-53 180.3 26.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD31842.1 - 2.1e-08 33.5 19.5 4e-08 32.5 5.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD31842.1 - 1.2 7.6 18.7 0.046 12.3 1.6 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein MFS_1 PF07690.16 PVD31843.1 - 9.4e-58 195.8 23.2 1.3e-55 188.7 23.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD31843.1 - 1.2e-07 31.0 16.9 1.6e-06 27.3 3.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Lectin_C PF00059.21 PVD31844.1 - 5.1e-11 43.3 0.1 6.2e-10 39.8 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain VWD PF00094.25 PVD31844.1 - 6.6e-06 26.5 0.0 1.6e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain TerY_C PF15616.6 PVD31844.1 - 1.8 8.7 10.0 0.23 11.6 2.6 2.7 2 0 0 2 2 2 0 TerY-C metal binding domain Lectin_C PF00059.21 PVD31845.1 - 2.1e-14 54.2 0.0 2.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 PVD31845.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 PVD31846.1 - 7.1e-14 52.5 0.0 9.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD31847.1 - 7.2e-14 52.4 0.0 9.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD31848.1 - 1.2e-12 48.5 0.0 1.6e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD31849.1 - 1.7e-21 77.0 0.0 9.9e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 Lectin C-type domain Ig_3 PF13927.6 PVD31849.1 - 1.1e-07 32.3 0.0 2.7 8.6 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD31849.1 - 3.2e-05 23.9 0.0 0.59 10.2 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 PVD31849.1 - 5.7e-05 23.2 0.0 0.12 12.6 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD31849.1 - 0.00096 19.4 0.4 3.2 8.2 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain bMG6 PF17962.1 PVD31849.1 - 0.0017 18.5 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial macroglobulin domain 6 Izumo-Ig PF16706.5 PVD31849.1 - 0.059 13.4 0.1 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF2400 PF09674.10 PVD31849.1 - 0.28 11.1 8.3 0.43 10.5 5.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) CCDC-167 PF15188.6 PVD31849.1 - 0.32 11.3 8.3 2.7 8.4 2.7 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4164 PF13747.6 PVD31849.1 - 0.43 10.9 9.1 0.29 11.4 1.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) SCVP PF17619.2 PVD31849.1 - 0.91 10.4 6.2 2 9.3 0.0 3.5 3 1 0 3 3 3 0 Secreted clade V proteins Phage_GPO PF05929.11 PVD31849.1 - 2.9 7.5 11.4 0.33 10.6 5.0 2.3 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Somatomedin_B PF01033.17 PVD31849.1 - 4.9 7.6 15.4 16 6.0 5.0 2.9 2 0 0 2 2 2 0 Somatomedin B domain Snapin_Pallidin PF14712.6 PVD31849.1 - 9.1 6.8 14.0 1.4 9.4 4.2 3.5 4 0 0 4 4 4 0 Snapin/Pallidin Lectin_C PF00059.21 PVD31850.1 - 2.5e-12 47.5 0.0 4.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD31851.1 - 1.2e-12 48.5 0.0 3.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Alpha-2-MRAP_C PF06401.11 PVD31851.1 - 0.0024 17.9 2.8 0.0055 16.7 2.8 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain DUF4349 PF14257.6 PVD31851.1 - 0.0026 17.2 1.1 0.0026 17.2 1.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4349) DUF3552 PF12072.8 PVD31851.1 - 0.067 12.6 12.3 0.17 11.3 6.8 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF3552) Ig_3 PF13927.6 PVD31851.1 - 0.072 13.7 0.0 9.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain ABC_tran_CTD PF16326.5 PVD31851.1 - 0.082 13.2 4.0 0.4 11.0 0.0 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF1664 PF07889.12 PVD31851.1 - 0.18 11.9 18.3 0.076 13.1 9.3 3.1 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PVD31851.1 - 0.31 11.1 15.8 2.3 8.3 4.2 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 PVD31851.1 - 0.45 9.9 14.7 1.9 7.9 9.9 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2400 PF09674.10 PVD31851.1 - 0.56 10.2 6.9 0.3 11.1 3.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) TRPM_tetra PF16519.5 PVD31851.1 - 0.59 10.3 12.9 3.5 7.8 6.5 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM PIN_8 PF18476.1 PVD31851.1 - 1.4 8.7 9.5 0.8 9.5 5.8 2.0 1 1 1 2 2 2 0 PIN like domain DUF5082 PF16888.5 PVD31851.1 - 3.8 7.8 9.2 6.1 7.1 1.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) MscS_porin PF12795.7 PVD31851.1 - 4.6 6.7 11.4 3.6 7.1 5.4 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Snapin_Pallidin PF14712.6 PVD31851.1 - 5.7 7.4 17.0 10 6.6 8.2 3.7 2 1 1 3 3 3 0 Snapin/Pallidin Laminin_II PF06009.12 PVD31851.1 - 8.2 6.4 13.5 0.16 12.0 2.4 2.9 3 0 0 3 3 3 0 Laminin Domain II Lectin_C PF00059.21 PVD31852.1 - 1.4e-11 45.1 0.0 2.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 PVD31853.1 - 9.2e-52 174.3 1.0 3.5e-12 47.0 0.0 4.8 4 0 0 4 4 4 4 Lectin C-type domain Alpha-2-MRAP_C PF06401.11 PVD31853.1 - 0.0027 17.7 3.2 0.0067 16.4 3.2 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Chordopox_A33R PF05966.12 PVD31853.1 - 0.0047 16.2 1.4 4.8 6.4 0.1 3.7 4 0 0 4 4 4 1 Chordopoxvirus A33R protein LemA PF04011.12 PVD31853.1 - 0.0055 16.6 4.6 0.23 11.3 0.5 2.5 2 0 0 2 2 2 2 LemA family DUF1664 PF07889.12 PVD31853.1 - 0.0095 16.0 14.3 0.027 14.5 9.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3552 PF12072.8 PVD31853.1 - 0.28 10.6 14.1 0.13 11.6 7.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) Baculo_PEP_C PF04513.12 PVD31853.1 - 0.35 10.9 14.6 2.1 8.4 3.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 PVD31853.1 - 0.5 10.6 5.4 0.68 10.2 0.0 3.5 2 1 3 5 5 5 0 ABC transporter C-terminal domain DUF4349 PF14257.6 PVD31853.1 - 0.65 9.4 10.6 0.038 13.4 4.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) PIN_8 PF18476.1 PVD31853.1 - 0.75 9.6 10.5 0.4 10.5 6.1 2.2 1 1 1 2 2 2 0 PIN like domain Occludin_ELL PF07303.13 PVD31853.1 - 1.1 10.0 9.7 20 6.0 0.0 4.5 3 1 1 4 4 4 0 Occludin homology domain Golgin_A5 PF09787.9 PVD31853.1 - 1.9 7.9 19.0 1.9 7.9 11.6 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 TRPM_tetra PF16519.5 PVD31853.1 - 2.9 8.1 13.0 5.7 7.1 6.5 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF2400 PF09674.10 PVD31853.1 - 3.3 7.6 8.4 1.1 9.2 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) DUF5082 PF16888.5 PVD31853.1 - 3.6 7.9 9.3 3.8 7.8 1.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) MscS_porin PF12795.7 PVD31853.1 - 4.3 6.8 11.2 1.1e+02 2.2 10.9 2.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Spectrin PF00435.21 PVD31853.1 - 6.5 7.3 14.4 9.5 6.8 0.4 3.5 2 1 1 3 3 3 0 Spectrin repeat Lectin_C PF00059.21 PVD31854.1 - 1.5e-12 48.2 0.0 3.3e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Lectin C-type domain Lectin_C PF00059.21 PVD31855.1 - 8.2e-12 45.8 0.0 1.6e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 PVD31856.1 - 2.6e-12 47.0 2.3 6.6e-05 23.2 0.5 3.9 4 0 0 4 4 4 2 CUB domain mRNA_cap_enzyme PF01331.19 PVD31857.1 - 1.3e-71 240.5 0.0 1.9e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 PVD31857.1 - 1.3e-19 70.8 0.0 2.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 PVD31857.1 - 9.9e-11 41.6 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD31857.1 - 0.0098 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 PVD31857.1 - 0.03 13.9 0.1 0.081 12.5 0.1 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PVD31857.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipocalin PF00061.23 PVD31858.1 - 1.1e-11 45.1 0.1 1.4e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 PVD31858.1 - 2.3e-05 24.3 0.2 3.4e-05 23.8 0.2 1.2 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF5128 PF17170.4 PVD31858.1 - 0.00018 20.7 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 6-bladed beta-propeller Ribosomal_L30_N PF08079.12 PVD31859.1 - 2.2e-26 91.9 14.9 4.1e-26 91.0 14.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 PVD31859.1 - 4.8e-21 74.4 0.9 4.8e-21 74.4 0.9 2.3 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e zf-CCHC PF00098.23 PVD31861.1 - 0.00071 19.5 0.9 0.0014 18.6 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD31861.1 - 0.0055 16.5 1.1 0.01 15.6 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PVD31861.1 - 0.083 12.6 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle dsrm PF00035.26 PVD31863.1 - 2.9e-45 152.8 1.1 6.4e-12 46.0 0.0 5.5 5 0 0 5 5 5 4 Double-stranded RNA binding motif Staufen_C PF16482.5 PVD31863.1 - 3.5e-19 69.0 1.3 9.9e-18 64.3 0.1 3.5 4 0 0 4 4 4 1 Staufen C-terminal domain DND1_DSRM PF14709.7 PVD31863.1 - 6.5e-05 23.1 8.6 0.0077 16.5 0.0 5.4 5 1 0 5 5 5 1 double strand RNA binding domain from DEAD END PROTEIN 1 zf-RING-like PF08746.11 PVD31864.1 - 0.065 13.5 0.2 0.065 13.5 0.2 1.9 2 0 0 2 2 2 0 RING-like domain Tyrosinase PF00264.20 PVD31865.1 - 6.3e-263 867.0 76.7 9.9e-35 120.8 0.2 13.2 8 7 2 10 10 10 10 Common central domain of tyrosinase Haemocyan_bet_s PF14830.6 PVD31865.1 - 3.6e-262 849.2 0.0 5.1e-37 126.0 0.0 9.0 9 0 0 9 9 9 8 Haemocyanin beta-sandwich DUF5053 PF16476.5 PVD31865.1 - 0.0098 15.5 1.2 4.3 7.1 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF5053) TMEM18 PF14770.6 PVD31866.1 - 8.1e-29 100.0 1.4 1.1e-28 99.6 1.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Cytochrom_B558a PF05038.13 PVD31866.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Indigoidine_A PF04227.12 PVD31867.1 - 5.8e-126 419.7 4.5 7.6e-126 419.4 4.5 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 PVD31867.1 - 7.3e-29 101.0 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Claudin_2 PF13903.6 PVD31868.1 - 8.4e-13 48.5 14.9 1.3e-12 47.9 14.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD31868.1 - 0.0027 17.7 15.3 0.011 15.7 15.2 1.8 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF3112 PF11309.8 PVD31868.1 - 0.018 14.5 1.9 0.018 14.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Clc-like PF07062.12 PVD31868.1 - 0.15 11.5 11.9 0.07 12.6 0.9 2.3 1 1 1 2 2 2 0 Clc-like Claudin_2 PF13903.6 PVD31869.1 - 2.7e-14 53.4 12.5 5.4e-14 52.4 12.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD31869.1 - 2e-06 27.9 14.4 1.4e-05 25.1 14.4 2.1 1 1 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 PVD31869.1 - 1.8e-05 24.7 5.9 0.0085 16.0 1.3 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF2254 PF10011.9 PVD31869.1 - 0.24 10.2 0.4 0.46 9.2 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Claudin_2 PF13903.6 PVD31870.1 - 1.4e-12 47.8 8.2 1.9e-12 47.4 8.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction GSG-1 PF07803.11 PVD31870.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.6 1 1 0 1 1 1 0 GSG1-like protein SHR3_chaperone PF08229.11 PVD31870.1 - 0.095 11.7 1.0 0.13 11.2 1.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 DUF202 PF02656.15 PVD31870.1 - 3.8 8.0 7.6 4 7.9 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Claudin_2 PF13903.6 PVD31871.1 - 1.3e-13 51.1 10.8 2e-13 50.6 10.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD31871.1 - 0.00022 21.5 11.1 0.00074 19.8 11.1 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 PVD31871.1 - 0.13 12.1 11.8 0.56 10.1 11.8 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like HXXEE PF13787.6 PVD31871.1 - 4.1 8.3 10.5 2.4 9.0 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function with HXXEE motif Claudin_2 PF13903.6 PVD31872.1 - 7.9e-15 55.1 5.4 9.5e-15 54.9 5.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD31872.1 - 2.7e-06 27.4 1.6 3.3e-06 27.1 1.6 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like EpsG PF14897.6 PVD31872.1 - 0.0065 15.8 3.1 0.0082 15.5 3.1 1.1 1 0 0 1 1 1 1 EpsG family Syndecan PF01034.20 PVD31872.1 - 0.11 12.5 0.8 0.11 12.5 0.8 2.4 2 0 0 2 2 2 0 Syndecan domain Ninjurin PF04923.12 PVD31872.1 - 2.9 7.9 9.1 46 4.0 0.3 2.2 1 1 1 2 2 2 0 Ninjurin P5CR_dimer PF14748.6 PVD31873.1 - 1.3e-43 147.4 2.0 3.1e-43 146.2 2.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PVD31873.1 - 8.1e-18 64.8 0.2 2.2e-17 63.4 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 PVD31873.1 - 1.6e-07 30.6 0.3 3.7e-07 29.4 0.3 1.6 1 1 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 PVD31873.1 - 3.2e-05 24.0 0.2 7.3e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 PVD31873.1 - 8.1e-05 22.8 0.1 0.00072 19.8 0.1 2.2 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PVD31873.1 - 0.0092 15.4 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIID-31kDa PF02291.15 PVD31873.1 - 0.16 12.0 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit 3HCDH_N PF02737.18 PVD31873.1 - 4.7 7.1 6.8 2.3 8.1 0.1 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rad21_Rec8_N PF04825.13 PVD31874.1 - 9.3e-41 138.4 0.0 2e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PVD31874.1 - 1.4e-15 56.3 0.1 1.8e-14 52.7 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 PVD31874.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA AA_permease PF00324.21 PVD31876.1 - 3.9e-24 85.1 48.3 2e-10 39.9 5.3 4.0 2 1 2 4 4 4 4 Amino acid permease DUF5418 PF17439.2 PVD31876.1 - 0.53 10.4 8.3 1 9.4 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Serinc PF03348.15 PVD31877.1 - 5.7e-173 575.8 20.3 6.4e-173 575.6 20.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cytomega_US3 PF05963.11 PVD31877.1 - 0.059 13.0 1.3 0.12 12.0 1.3 1.5 1 0 0 1 1 1 0 Cytomegalovirus US3 protein PKI PF02827.16 PVD31878.1 - 4.8e-14 52.3 0.3 9.3e-14 51.4 0.1 1.6 1 1 0 1 1 1 1 cAMP-dependent protein kinase inhibitor PI31_Prot_N PF11566.8 PVD31879.1 - 6.1e-20 71.7 0.0 7.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 PVD31879.1 - 4.1e-06 27.9 19.5 1.4e-05 26.1 19.5 2.1 1 1 0 1 1 1 1 PI31 proteasome regulator Glycophorin_A PF01102.18 PVD31880.1 - 0.043 14.1 0.7 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Glycophorin A Asp5 PF17000.5 PVD31880.1 - 0.081 13.1 0.4 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 GMC_oxred_C PF05199.13 PVD31881.1 - 3.9e-23 82.6 3.4 1e-10 42.3 0.3 2.0 2 0 0 2 2 2 2 GMC oxidoreductase Autophagy_C PF10381.9 PVD31881.1 - 0.37 10.3 3.9 9.5 5.8 0.4 2.3 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal GMC_oxred_C PF05199.13 PVD31882.1 - 2.8e-10 40.9 0.2 4.2e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PVD31883.1 - 1.2e-12 48.5 0.1 1.8e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GILT PF03227.16 PVD31884.1 - 1.6e-25 89.4 1.6 3e-25 88.5 1.6 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SapA PF02199.15 PVD31884.1 - 0.0037 17.5 0.1 0.011 16.0 0.1 1.9 1 0 0 1 1 1 1 Saposin A-type domain ORF6C PF10552.9 PVD31885.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 ORF6C domain DUF3829 PF12889.7 PVD31885.1 - 0.023 14.2 0.4 0.041 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3486 PF11985.8 PVD31885.1 - 0.042 14.3 0.4 0.073 13.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ABC_tran_Xtn PF12848.7 PVD31885.1 - 0.55 10.3 1.5 1.2 9.2 1.5 1.5 1 0 0 1 1 1 0 ABC transporter ORF6C PF10552.9 PVD31886.1 - 0.076 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 ORF6C domain adh_short PF00106.25 PVD31887.1 - 1.6e-46 158.3 0.4 1.9e-46 158.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD31887.1 - 1.1e-32 113.5 0.2 1.3e-32 113.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD31887.1 - 1.2e-09 38.3 0.4 1.7e-09 37.8 0.4 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PVD31888.1 - 1.1e-47 162.1 0.6 1.4e-47 161.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD31888.1 - 7.9e-35 120.5 0.1 1e-34 120.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD31888.1 - 1.5e-10 41.3 0.6 2.1e-10 40.8 0.6 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 PVD31888.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 PVD31888.1 - 0.055 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Elongin_A PF06881.11 PVD31889.1 - 6.3e-22 78.1 0.0 6.3e-22 78.1 0.0 5.3 5 1 1 6 6 6 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 PVD31889.1 - 2.2e-11 43.6 0.0 7.6e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.9 PVD31891.1 - 0.0074 16.1 0.8 0.022 14.5 0.8 1.8 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain TSGP1 PF07771.11 PVD31892.1 - 0.016 15.4 0.9 0.016 15.4 0.9 4.6 4 1 1 5 5 5 0 Tick salivary peptide group 1 TMEM154 PF15102.6 PVD31892.1 - 0.1 12.5 0.5 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family zf-RING_UBOX PF13445.6 PVD31893.1 - 1.6e-11 44.0 3.0 1.6e-11 44.0 3.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD31893.1 - 4.5e-08 33.1 1.6 4.5e-08 33.1 1.6 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD31893.1 - 1.3e-07 31.3 2.0 1.3e-07 31.3 2.0 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD31893.1 - 1.1e-06 28.3 3.5 1.1e-06 28.3 3.5 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD31893.1 - 4.4e-06 26.9 3.3 4.4e-06 26.9 3.3 3.3 4 0 0 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD31893.1 - 2e-05 24.3 1.4 2e-05 24.3 1.4 2.9 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD31893.1 - 0.00031 20.6 4.1 0.00031 20.6 4.1 3.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD31893.1 - 0.0048 16.7 3.2 0.0048 16.7 3.2 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 CEBP_ZZ PF16366.5 PVD31893.1 - 0.0074 16.5 9.9 0.011 16.0 2.1 2.8 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain CdvA PF18822.1 PVD31893.1 - 0.015 15.1 2.3 0.027 14.3 2.3 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain ApoO PF09769.9 PVD31893.1 - 0.072 13.1 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Apolipoprotein O zf-RING_11 PF17123.5 PVD31893.1 - 0.14 11.9 7.4 0.55 10.0 7.4 2.1 1 0 0 1 1 1 0 RING-like zinc finger DUF641 PF04859.12 PVD31893.1 - 0.15 12.4 2.5 0.29 11.5 2.5 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF883 PF05957.13 PVD31893.1 - 0.24 12.0 3.5 0.41 11.3 2.6 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Bacillus_HBL PF05791.11 PVD31893.1 - 0.39 10.5 1.7 0.91 9.3 1.6 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HrpJ PF07201.11 PVD31893.1 - 0.54 10.6 4.1 0.94 9.8 4.1 1.3 1 0 0 1 1 1 0 HrpJ-like domain DUF4637 PF15470.6 PVD31893.1 - 2 8.1 5.1 0.38 10.5 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) zf-RING_6 PF14835.6 PVD31893.1 - 4 7.4 9.7 0.094 12.6 1.1 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein BTB PF00651.31 PVD31894.1 - 2.2e-23 82.6 0.0 3.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 PVD31894.1 - 2.6e-23 81.1 67.5 0.00051 20.3 5.0 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD31894.1 - 3.8e-20 71.3 49.6 1.4e-06 28.5 3.6 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD31894.1 - 1.9e-18 65.6 69.0 0.0024 18.5 1.8 8.0 8 0 0 8 8 8 7 C2H2-type zinc finger BACK PF07707.15 PVD31894.1 - 8.7e-09 35.4 0.1 2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2_jaz PF12171.8 PVD31894.1 - 1.5e-07 31.5 43.9 0.031 14.6 1.4 7.7 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD31894.1 - 6e-05 22.9 66.0 0.00081 19.3 3.2 7.7 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2HC5 PF06221.13 PVD31894.1 - 0.17 11.9 0.1 0.17 11.9 0.1 5.7 7 0 0 7 7 7 0 Putative zinc finger motif, C2HC5-type UBZ_FAAP20 PF15750.5 PVD31894.1 - 0.42 10.6 8.6 12 5.9 0.2 5.0 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger SEP PF08059.13 PVD31895.1 - 1.3e-17 64.1 0.0 4.5e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 PVD31895.1 - 9.9e-10 38.5 0.0 6.2e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 UBX domain XLF PF09302.11 PVD31895.1 - 0.038 14.2 3.3 0.25 11.5 0.2 2.8 3 0 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Angiomotin_C PF12240.8 PVD31895.1 - 0.046 13.3 4.5 0.13 11.8 3.1 2.3 1 1 1 2 2 2 0 Angiomotin C terminal DUF4798 PF16055.5 PVD31895.1 - 0.11 12.7 1.2 0.22 11.8 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4798) ATG16 PF08614.11 PVD31895.1 - 1.1 9.4 8.7 0.59 10.3 5.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) 7tm_1 PF00001.21 PVD31896.1 - 1.3e-18 67.3 15.8 1.3e-18 67.3 15.8 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD31896.1 - 4.3e-07 29.5 15.4 2.9e-06 26.8 15.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw FAM75 PF14650.6 PVD31896.1 - 0.39 10.2 0.9 0.59 9.6 0.9 1.2 1 0 0 1 1 1 0 FAM75 family Tudor-knot PF11717.8 PVD31899.1 - 2.2e-07 30.6 1.0 3.2e-06 26.9 0.5 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain PHD PF00628.29 PVD31899.1 - 3.7e-06 26.7 12.4 7.4e-06 25.8 12.4 1.5 1 0 0 1 1 1 1 PHD-finger Tudor_2 PF18104.1 PVD31899.1 - 4e-06 26.4 0.3 7.1e-05 22.4 0.3 2.4 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain MBT PF02820.18 PVD31899.1 - 7.5e-06 26.2 0.0 2.6e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 mbt repeat zf-C2H2 PF00096.26 PVD31899.1 - 0.0018 18.6 0.8 0.0018 18.6 0.8 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Agenet PF05641.12 PVD31899.1 - 0.0067 16.9 0.1 0.026 15.0 0.1 2.1 1 0 0 1 1 1 1 Agenet domain SAWADEE PF16719.5 PVD31899.1 - 0.036 14.1 0.6 0.094 12.7 0.6 1.7 1 0 0 1 1 1 0 SAWADEE domain GST_C PF00043.25 PVD31900.1 - 5.4e-12 45.8 0.0 8.7e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD31900.1 - 5.8e-12 45.7 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PVD31900.1 - 2.9e-11 43.5 0.0 5.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD31900.1 - 3.1e-11 43.4 0.0 6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PVD31900.1 - 7.8e-11 42.2 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD31900.1 - 3.2e-08 33.5 0.0 7.7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PVD31900.1 - 0.00053 20.7 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 PVD31900.1 - 0.02 15.4 0.0 0.13 12.8 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.27 PVD31901.1 - 8.1e-16 58.6 0.3 1.3e-15 57.9 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 PVD31901.1 - 3.6e-13 49.3 0.2 7.9e-13 48.2 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 PVD31901.1 - 0.0097 15.4 0.3 0.027 14.0 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 PVD31902.1 - 7e-69 232.1 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31902.1 - 2.8e-51 174.3 0.0 3.9e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 PVD31902.1 - 3.2e-23 81.5 3.8 9e-23 80.1 3.8 1.8 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 PVD31902.1 - 2.4e-07 29.9 1.0 3.6e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD31902.1 - 0.0054 15.7 0.5 0.034 13.1 0.5 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD31902.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Abi_2 PF07751.11 PVD31902.1 - 0.02 15.2 0.6 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 Abi-like protein Phage_Mu_Gam PF07352.12 PVD31902.1 - 0.13 12.1 2.0 0.32 10.9 2.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein 7tm_1 PF00001.21 PVD31903.1 - 9.7e-32 110.3 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD31903.1 - 8.6e-06 25.3 6.6 8.6e-06 25.3 6.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx MARVEL PF01284.23 PVD31903.1 - 0.014 15.4 6.1 0.94 9.5 2.7 3.2 3 0 0 3 3 3 0 Membrane-associating domain UPF0182 PF03699.13 PVD31903.1 - 0.089 10.9 0.8 0.14 10.2 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) 7tm_1 PF00001.21 PVD31904.1 - 3.8e-28 98.5 3.2 5.3e-28 98.1 3.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 PVD31904.1 - 0.0057 16.4 17.7 0.0089 15.7 2.6 2.9 3 0 0 3 3 3 2 Srg family chemoreceptor TctB PF07331.11 PVD31904.1 - 7.3 6.9 13.2 1.7 9.0 0.4 3.5 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family 7tm_1 PF00001.21 PVD31906.1 - 6.3e-27 94.5 0.1 9.3e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3084 PF11283.8 PVD31906.1 - 0.33 11.0 2.6 0.38 10.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) DUF927 PF06048.11 PVD31907.1 - 0.13 11.8 1.3 0.23 11.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Erythro_esteras PF05139.14 PVD31907.1 - 2.3 7.9 8.0 6.6 6.4 8.0 1.6 1 1 0 1 1 1 0 Erythromycin esterase Kelch_1 PF01344.25 PVD31908.1 - 1.1e-79 261.7 11.6 9.8e-17 60.3 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 PVD31908.1 - 6.9e-54 178.5 0.9 5.9e-11 42.3 0.0 7.0 5 1 2 7 7 7 6 Kelch motif Kelch_3 PF13415.6 PVD31908.1 - 1.3e-33 114.6 0.4 3.8e-09 36.6 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 PVD31908.1 - 5.6e-33 113.1 3.3 1.1e-32 112.1 1.8 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 PVD31908.1 - 1.8e-31 107.9 4.5 2.9e-07 30.4 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD31908.1 - 2.9e-30 103.1 0.4 2.1e-05 24.3 0.1 7.1 7 0 0 7 7 7 5 Kelch motif BTB PF00651.31 PVD31908.1 - 4.6e-29 100.9 0.5 1.3e-28 99.4 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 PVD31908.1 - 3.4e-19 68.4 1.5 0.012 15.6 0.0 6.0 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 PVD31908.1 - 0.00021 21.6 7.7 5.5 7.6 0.0 4.7 5 0 0 5 5 5 2 PQQ-like domain DUF5122 PF17164.4 PVD31908.1 - 0.29 11.4 0.9 11 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller LRR_6 PF13516.6 PVD31909.1 - 0.00017 21.4 8.1 14 6.1 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 PVD31909.1 - 0.0015 18.9 16.8 0.28 11.7 1.5 5.5 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD31909.1 - 0.017 14.9 17.2 0.48 10.2 0.7 5.5 4 2 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 PVD31909.1 - 0.021 15.3 14.3 53 4.9 0.0 7.2 7 0 0 7 7 7 0 Leucine Rich Repeat DUF1533 PF07550.11 PVD31909.1 - 0.14 12.1 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) DnaJ PF00226.31 PVD31910.1 - 1.5e-17 63.5 1.0 1.5e-17 63.5 1.0 2.3 2 0 0 2 2 2 1 DnaJ domain Phtf-FEM1B_bdg PF12129.8 PVD31911.1 - 1.5e-56 190.5 4.9 4.2e-56 189.1 4.9 1.8 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Mito_carr PF00153.27 PVD31913.1 - 5e-66 218.7 3.3 1.2e-22 79.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein V-ATPase_H_N PF03224.14 PVD31914.1 - 1.5e-107 359.6 9.5 1.5e-107 359.6 9.5 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 PVD31914.1 - 1.6e-46 157.2 4.8 5.7e-46 155.4 0.2 3.1 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 PVD31914.1 - 2e-07 31.3 1.7 0.078 13.4 0.0 4.0 4 1 0 4 4 4 2 HEAT repeats Arm PF00514.23 PVD31914.1 - 4.4e-06 26.5 1.6 0.96 9.6 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 PVD31914.1 - 4.9e-05 22.9 0.4 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 1 Armadillo-like DUF2326 PF10088.9 PVD31914.1 - 0.0012 18.6 0.2 0.005 16.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2326) IZUMO PF15005.6 PVD31914.1 - 0.011 16.2 1.8 0.033 14.7 0.8 2.4 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HEAT PF02985.22 PVD31914.1 - 0.012 15.8 0.0 0.36 11.2 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat RPAP3_C PF13877.6 PVD31914.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.8 4 0 0 4 4 4 0 Potential Monad-binding region of RPAP3 SIL1 PF16782.5 PVD31914.1 - 0.88 8.7 6.1 1.5 8.0 0.2 2.6 2 1 0 2 2 2 0 Nucleotide exchange factor SIL1 Ependymin PF00811.18 PVD31915.1 - 9.8e-08 32.3 0.1 1.2e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 Ependymin Trypsin PF00089.26 PVD31916.1 - 5.3e-37 127.8 1.7 6.1e-37 127.6 1.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 PVD31917.1 - 2.9e-93 311.7 19.5 1.8e-50 171.8 7.9 2.0 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 PVD31917.1 - 1.8e-10 41.9 5.3 3e-05 24.9 0.8 2.6 2 1 0 2 2 2 2 Trypsin-like peptidase domain Cys_Knot_tox PF17486.2 PVD31917.1 - 5.2 7.4 6.6 1.2 9.4 0.3 3.0 3 0 0 3 3 3 0 Cystine knot toxins Trypsin PF00089.26 PVD31918.1 - 8.5e-48 163.1 9.4 9.9e-48 162.9 9.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD31918.1 - 1.1e-05 26.4 0.5 1.7e-05 25.8 0.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain XendoU PF09412.10 PVD31919.1 - 4.6e-126 419.4 1.1 2.8e-73 246.4 0.0 2.1 2 0 0 2 2 2 2 Endoribonuclease XendoU Somatomedin_B PF01033.17 PVD31919.1 - 6.5e-09 36.1 16.3 1.2e-08 35.2 16.3 1.4 1 0 0 1 1 1 1 Somatomedin B domain Attachment_P66 PF11263.8 PVD31919.1 - 0.071 12.4 0.3 8.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi attachment protein P66 DUF1533 PF07550.11 PVD31919.1 - 0.13 12.2 0.0 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) DUF1897 PF09005.10 PVD31919.1 - 4.3 6.9 5.1 23 4.6 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) XendoU PF09412.10 PVD31920.1 - 1.5e-70 237.5 0.1 1.7e-70 237.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU XendoU PF09412.10 PVD31921.1 - 8.2e-64 215.4 0.0 9.4e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU AAA_30 PF13604.6 PVD31922.1 - 8.7e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PVD31922.1 - 3.8e-05 24.0 0.1 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD31922.1 - 0.00012 22.5 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD31922.1 - 0.00029 21.3 0.1 0.00094 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF3987 PF13148.6 PVD31922.1 - 0.00065 18.8 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_28 PF13521.6 PVD31922.1 - 0.0013 19.0 0.2 0.3 11.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain PIF1 PF05970.14 PVD31922.1 - 0.0032 16.7 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA PF00004.29 PVD31922.1 - 0.012 16.0 0.2 0.032 14.6 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 PVD31922.1 - 0.044 13.0 0.8 0.42 9.7 0.1 2.4 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 PVD31922.1 - 0.05 14.1 0.0 0.23 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain Hydrolase PF00702.26 PVD31922.1 - 0.093 13.0 0.0 0.37 11.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_transf_4 PF13439.6 PVD31922.1 - 0.1 12.6 0.1 32 4.5 0.0 3.1 3 0 0 3 3 3 0 Glycosyltransferase Family 4 PhoH PF02562.16 PVD31922.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CPSase_L_D2 PF02786.17 PVD31922.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_5 PF07728.14 PVD31922.1 - 0.14 12.2 0.3 3 7.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) HLH PF00010.26 PVD31923.1 - 2.2e-09 37.1 4.1 3e-09 36.7 4.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 PVD31924.1 - 0.0058 16.8 0.2 0.01 16.0 0.2 1.4 1 0 0 1 1 1 1 Hairy Orange MRP-S35 PF10246.9 PVD31925.1 - 1.2e-21 76.6 0.0 1.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.23 PVD31925.1 - 0.0011 19.2 0.0 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain Psu PF07455.11 PVD31925.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) HD_3 PF13023.6 PVD31926.1 - 2.6e-47 160.8 0.3 3.3e-47 160.5 0.3 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 PVD31926.1 - 1.1e-12 48.1 3.2 3.2e-12 46.6 3.2 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 PVD31926.1 - 2.4e-05 24.6 0.2 5.6e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 HD domain Pkip-1 PF06878.11 PVD31926.1 - 0.029 14.5 0.9 0.056 13.6 0.9 1.6 1 1 0 1 1 1 0 Pkip-1 protein Organ_specific PF10950.8 PVD31926.1 - 0.065 13.9 0.1 0.11 13.2 0.1 1.4 1 0 0 1 1 1 0 Organ specific protein PRP1_N PF06424.12 PVD31927.1 - 2.8e-56 190.0 7.4 2.8e-56 190.0 7.4 1.9 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 PVD31927.1 - 1.1e-36 122.4 29.3 3e-06 27.6 0.0 14.8 6 3 9 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.6 PVD31927.1 - 7.5e-26 90.4 7.0 2e-06 28.2 0.0 8.8 8 2 1 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 PVD31927.1 - 1.7e-14 53.1 2.8 0.0095 16.3 0.0 7.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD31927.1 - 2.4e-13 49.1 8.1 0.027 14.6 0.0 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD31927.1 - 2.9e-11 43.8 15.1 0.0044 17.6 0.0 8.3 6 2 2 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD31927.1 - 6.6e-09 35.8 1.7 6.3 7.7 0.0 9.1 9 0 0 9 9 8 1 Tetratricopeptide repeat NARP1 PF12569.8 PVD31927.1 - 1.4e-08 34.1 6.3 0.016 14.1 0.0 5.6 4 1 2 6 6 6 3 NMDA receptor-regulated protein 1 FAT PF02259.23 PVD31927.1 - 2.5e-08 33.6 11.2 0.00034 19.9 0.8 4.3 1 1 1 3 3 3 2 FAT domain TPR_9 PF13371.6 PVD31927.1 - 4.8e-07 29.8 4.4 0.19 11.9 0.0 5.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD31927.1 - 5.7e-07 29.1 0.1 0.75 9.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD31927.1 - 1.4e-06 27.8 0.0 0.14 11.9 0.0 6.1 5 1 2 7 7 7 1 TPR repeat TPR_8 PF13181.6 PVD31927.1 - 3.7e-06 26.7 0.1 16 6.0 0.0 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD31927.1 - 4.3e-06 26.6 3.6 0.0043 16.8 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat-like domain Suf PF05843.14 PVD31927.1 - 1.2e-05 25.5 0.2 3.4 7.6 0.0 5.5 6 1 0 7 7 7 1 Suppressor of forked protein (Suf) ChAPs PF09295.10 PVD31927.1 - 0.00031 19.9 5.9 0.15 11.1 1.6 3.5 3 1 1 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 PVD31927.1 - 0.00041 19.7 11.9 2.4 7.3 0.1 6.1 3 1 3 6 6 6 2 Tetratricopeptide repeat DUF3808 PF10300.9 PVD31927.1 - 0.001 17.9 0.5 2.9 6.5 0.0 4.2 3 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 PVD31927.1 - 0.025 14.8 10.9 33 4.9 0.1 6.8 5 2 2 7 7 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 PVD31927.1 - 0.034 13.3 19.2 0.78 8.8 0.1 5.4 5 1 1 6 6 6 0 NRDE-2, necessary for RNA interference Wzy_C_2 PF11846.8 PVD31927.1 - 0.046 13.7 1.6 35 4.3 0.0 4.4 2 1 3 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal Tho2 PF11262.8 PVD31927.1 - 1.6 7.8 4.9 2 7.6 1.8 2.5 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 VIR_N PF15912.5 PVD31927.1 - 6 6.4 7.7 11 5.6 7.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Lectin_C PF00059.21 PVD31928.1 - 4.8e-12 46.6 0.7 1.2e-11 45.3 0.2 2.1 2 0 0 2 2 1 1 Lectin C-type domain TACC_C PF05010.14 PVD31928.1 - 0.0012 18.6 0.9 0.0012 18.6 0.9 1.9 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF148 PF02520.17 PVD31928.1 - 0.0022 18.1 3.3 0.12 12.5 0.3 2.5 1 1 1 2 2 2 1 Domain of unknown function DUF148 IFT57 PF10498.9 PVD31928.1 - 0.0027 16.7 3.1 0.0071 15.4 2.9 1.5 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 PVD31928.1 - 0.0037 17.3 9.9 0.26 11.3 1.9 3.0 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 PVD31928.1 - 0.0058 17.1 7.2 12 6.5 0.4 4.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoLp-III PF07464.11 PVD31928.1 - 0.0085 16.2 2.4 0.25 11.4 0.0 2.7 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) SF-assemblin PF06705.11 PVD31928.1 - 0.012 15.0 3.4 0.1 11.9 0.2 2.4 1 1 1 2 2 2 0 SF-assemblin/beta giardin LXG PF04740.12 PVD31928.1 - 0.013 15.2 3.9 0.057 13.1 0.7 2.3 1 1 0 2 2 2 0 LXG domain of WXG superfamily DUF1664 PF07889.12 PVD31928.1 - 0.017 15.2 3.8 0.29 11.2 0.2 3.3 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 PVD31928.1 - 0.027 14.1 4.1 0.04 13.5 4.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 PVD31928.1 - 0.028 14.7 2.1 10 6.4 0.9 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Tmemb_cc2 PF10267.9 PVD31928.1 - 0.03 13.5 4.7 6 5.9 0.9 2.9 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Syntaxin_2 PF14523.6 PVD31928.1 - 0.033 14.6 6.3 0.56 10.6 0.2 2.8 3 0 0 3 3 2 0 Syntaxin-like protein Apolipoprotein PF01442.18 PVD31928.1 - 0.04 13.8 11.7 2.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tup_N PF08581.10 PVD31928.1 - 0.049 13.9 0.4 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Tup N-terminal FAM184 PF15665.5 PVD31928.1 - 0.063 13.1 6.3 0.022 14.5 2.8 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4407 PF14362.6 PVD31928.1 - 0.069 12.5 7.6 1.8 7.8 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Flagellar_rod PF05149.12 PVD31928.1 - 0.099 12.1 4.1 0.3 10.5 0.8 2.2 1 1 0 2 2 2 0 Paraflagellar rod protein Spc7 PF08317.11 PVD31928.1 - 0.1 11.5 7.3 0.87 8.4 2.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin PF00804.25 PVD31928.1 - 0.11 12.2 1.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Syntaxin V_ATPase_I PF01496.19 PVD31928.1 - 0.11 10.4 0.9 0.26 9.2 0.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 PVD31928.1 - 0.14 12.6 4.3 0.31 11.5 0.2 3.3 3 1 0 3 3 3 0 Snapin/Pallidin IL32 PF15225.6 PVD31928.1 - 0.14 12.5 2.8 0.94 9.9 0.3 3.2 3 1 1 4 4 3 0 Interleukin 32 Not3 PF04065.15 PVD31928.1 - 0.2 11.1 0.9 0.37 10.2 0.6 1.5 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Allexi_40kDa PF05549.11 PVD31928.1 - 0.2 11.1 4.9 2.9 7.3 0.9 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein Toxin_trans PF07952.12 PVD31928.1 - 0.23 10.5 0.5 0.4 9.7 0.3 1.5 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain COG2 PF06148.11 PVD31928.1 - 0.24 11.5 3.9 12 6.0 0.2 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 PVD31928.1 - 0.27 11.3 2.4 2.4 8.3 0.3 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF948 PF06103.11 PVD31928.1 - 0.28 11.5 5.7 3.5 7.9 0.6 3.5 3 1 2 5 5 3 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 PVD31928.1 - 0.31 10.5 3.5 5 6.5 1.4 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 KxDL PF10241.9 PVD31928.1 - 0.63 10.4 7.1 1.1 9.6 0.5 3.1 3 1 2 5 5 4 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 PVD31928.1 - 0.91 9.0 6.0 5.1 6.6 5.8 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.11 PVD31928.1 - 0.97 9.5 4.9 0.39 10.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) HAUS-augmin3 PF14932.6 PVD31928.1 - 1.3 8.5 5.8 1.8 8.1 0.1 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Lectin_N PF03954.14 PVD31928.1 - 1.5 8.6 6.1 3.8 7.3 0.4 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Plasmid_RAQPRD PF09686.10 PVD31928.1 - 1.6 9.0 5.5 1.1 9.5 0.9 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SKA2 PF16740.5 PVD31928.1 - 4 7.3 6.4 42 4.0 0.1 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Laminin_II PF06009.12 PVD31928.1 - 4.4 7.3 7.7 6.8 6.7 0.3 3.1 2 1 2 4 4 4 0 Laminin Domain II Matrilin_ccoil PF10393.9 PVD31928.1 - 4.5 7.2 8.0 1.7 8.5 0.1 3.8 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin MscS_porin PF12795.7 PVD31928.1 - 8.9 5.8 9.5 5.1 6.6 1.6 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CLZ PF16526.5 PVD31928.1 - 9.4 6.7 9.2 32 5.0 0.2 4.0 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lectin_C PF00059.21 PVD31929.1 - 8e-06 26.5 0.0 2.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Laminin_II PF06009.12 PVD31929.1 - 0.0026 17.8 17.9 0.086 12.9 5.1 2.8 1 1 0 2 2 2 2 Laminin Domain II Exonuc_VII_L PF02601.15 PVD31929.1 - 0.96 9.0 21.4 85 2.6 21.4 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 PVD31929.1 - 1.1 7.2 18.1 1.6 6.6 8.2 1.6 1 1 0 1 1 1 0 Prominin TcpS PF17456.2 PVD31929.1 - 1.4 9.0 10.4 0.31 11.1 0.9 2.6 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S SKA2 PF16740.5 PVD31929.1 - 2 8.2 18.5 4.4 7.1 5.6 2.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 PVD31929.1 - 2.1 8.4 26.0 7.9 6.5 14.0 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 PVD31929.1 - 2.1 7.6 17.1 0.11 11.9 5.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 PVD31929.1 - 4.3 7.8 18.2 0.64 10.4 4.0 3.8 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 PVD31929.1 - 9.7 6.3 22.3 0.73 10.0 1.1 3.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Lectin_C PF00059.21 PVD31930.1 - 9.7e-11 42.4 0.2 5.2e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain MRF_C2 PF13888.6 PVD31930.1 - 0.2 11.5 3.9 4.3 7.2 0.2 3.4 2 1 1 3 3 3 0 Myelin gene regulatory factor C-terminal domain 2 Gp-FAR-1 PF05823.12 PVD31930.1 - 0.61 10.4 6.4 0.28 11.5 0.9 2.6 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4407 PF14362.6 PVD31930.1 - 0.96 8.7 18.2 1.1 8.6 14.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 PVD31930.1 - 1.9 9.0 13.2 1.6 9.2 6.9 3.0 2 1 0 2 2 2 0 Spectrin repeat Phage_Mu_Gam PF07352.12 PVD31930.1 - 5.1 7.0 19.1 0.45 10.4 6.3 3.0 3 1 1 4 4 4 0 Bacteriophage Mu Gam like protein Laminin_II PF06009.12 PVD31930.1 - 6.2 6.8 31.1 0.92 9.5 5.4 4.0 2 1 2 4 4 4 0 Laminin Domain II Leu_zip PF15294.6 PVD31930.1 - 9.2 5.7 31.2 0.41 10.1 9.8 2.4 1 1 0 2 2 2 0 Leucine zipper Lectin_C PF00059.21 PVD31931.1 - 3.6e-10 40.5 0.0 1.5e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain HTH_30 PF13556.6 PVD31931.1 - 0.0053 16.5 0.3 7.4 6.5 0.0 3.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain Laminin_II PF06009.12 PVD31931.1 - 0.035 14.1 28.4 0.099 12.7 6.4 3.5 2 1 2 4 4 4 0 Laminin Domain II DUF4407 PF14362.6 PVD31931.1 - 0.17 11.2 18.2 0.023 14.1 8.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD31931.1 - 0.25 10.8 26.4 0.76 9.3 10.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit CLZ PF16526.5 PVD31931.1 - 0.29 11.5 25.6 0.14 12.5 3.8 4.4 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GCN5L1 PF06320.13 PVD31931.1 - 0.39 10.9 11.8 0.48 10.6 1.8 2.9 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) XhlA PF10779.9 PVD31931.1 - 0.65 10.2 16.8 0.75 10.0 1.8 4.4 3 1 1 4 4 4 0 Haemolysin XhlA SKA2 PF16740.5 PVD31931.1 - 0.93 9.3 22.5 7.2 6.4 6.9 3.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF3584 PF12128.8 PVD31931.1 - 2.3 5.6 26.3 4.7 4.6 26.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 PVD31931.1 - 2.6 8.1 33.3 0.53 10.3 11.1 4.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 PVD31931.1 - 3.5 8.1 29.0 0.17 12.3 7.5 4.0 3 1 0 3 3 3 0 Snapin/Pallidin ECM11 PF15463.6 PVD31931.1 - 3.6 8.2 9.9 1 9.9 5.4 2.1 1 1 1 2 2 2 0 Extracellular mutant protein 11 Imm3 PF14425.6 PVD31931.1 - 4.3 7.4 10.3 0.84 9.7 4.0 2.8 1 1 1 3 3 3 0 Immunity protein Imm3 ApoLp-III PF07464.11 PVD31931.1 - 5.1 7.2 25.2 2.2 8.4 9.6 2.7 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 PVD31931.1 - 5.9 6.9 24.2 0.15 12.1 6.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 PVD31931.1 - 8.2 6.6 26.4 0.16 12.2 8.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MMR_HSR1_C PF08438.10 PVD31931.1 - 8.6 7.0 8.8 13 6.4 0.1 3.3 1 1 2 3 3 3 0 GTPase of unknown function C-terminal Lectin_C PF00059.21 PVD31932.1 - 1.4e-12 48.3 2.5 1.7e-12 48.0 0.0 2.3 3 0 0 3 3 3 1 Lectin C-type domain Apolipoprotein PF01442.18 PVD31932.1 - 2.6e-06 27.5 7.1 3.6e-06 27.0 7.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 PVD31932.1 - 0.00069 19.5 4.7 0.017 14.9 3.1 2.0 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B DUF1640 PF07798.11 PVD31932.1 - 0.0064 16.6 7.9 0.0064 16.6 7.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) DUF5063 PF16702.5 PVD31932.1 - 0.03 14.7 0.3 0.078 13.4 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) SF-assemblin PF06705.11 PVD31932.1 - 0.093 12.1 8.0 0.16 11.3 7.4 1.6 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF2884 PF11101.8 PVD31932.1 - 0.15 11.5 8.2 0.081 12.4 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Colicin-DNase PF12639.7 PVD31932.1 - 0.18 12.6 0.8 0.58 11.0 0.0 2.1 1 1 2 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin Exonuc_VII_L PF02601.15 PVD31932.1 - 0.19 11.3 8.3 0.48 10.0 8.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF5633 PF18656.1 PVD31932.1 - 0.21 11.5 1.3 10 6.1 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5633) HSCB_C PF07743.13 PVD31932.1 - 0.25 11.9 2.8 1.2 9.6 0.2 2.9 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain Baculo_PEP_C PF04513.12 PVD31932.1 - 0.36 10.9 15.2 3.2 7.8 2.6 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 PVD31932.1 - 0.38 11.4 4.9 3.7 8.2 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.8 PVD31932.1 - 0.55 9.5 6.0 0.47 9.7 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.11 PVD31932.1 - 0.99 7.3 7.9 2.2 6.1 7.9 1.4 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 PVD31932.1 - 1.9 8.5 9.6 1.1 9.3 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 PVD31932.1 - 2.9 8.3 11.0 36 4.8 0.9 3.9 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 PVD31932.1 - 3.1 7.2 10.4 2.9 7.4 3.5 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 PVD31932.1 - 3.9 7.7 12.0 1.2 9.3 4.7 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family LPP PF04728.13 PVD31932.1 - 6.3 7.3 8.2 1.7 9.1 0.3 3.2 3 1 0 3 3 2 0 Lipoprotein leucine-zipper ApoLp-III PF07464.11 PVD31933.1 - 0.0093 16.1 16.7 0.019 15.1 3.3 3.2 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) DUF1053 PF06327.14 PVD31933.1 - 0.068 13.7 0.8 0.068 13.7 0.8 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) LOH1CR12 PF10158.9 PVD31933.1 - 0.084 12.9 4.9 0.06 13.4 0.9 2.5 2 1 0 2 2 2 0 Tumour suppressor protein HTH_1 PF00126.27 PVD31933.1 - 0.13 12.2 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF948 PF06103.11 PVD31933.1 - 0.38 11.1 8.0 0.41 10.9 0.6 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 PVD31933.1 - 1.3 6.8 16.7 2.2 6.1 16.4 1.5 1 1 0 1 1 1 0 Prominin DUF5082 PF16888.5 PVD31933.1 - 1.8 8.9 15.6 2.2 8.6 9.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Apolipoprotein PF01442.18 PVD31933.1 - 1.8 8.4 19.3 1.2 8.9 9.2 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD31933.1 - 1.9 8.5 12.8 5.6 7.0 0.7 3.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PdaC PF13739.6 PVD31933.1 - 6.1 7.9 8.1 4.7 8.3 0.9 3.1 2 1 1 3 3 3 0 Deacetylase PdaC Lectin_C PF00059.21 PVD31934.1 - 1.1e-09 39.0 0.4 4.3e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain Lectin_C PF00059.21 PVD31935.1 - 3.8e-08 34.0 1.3 0.00013 22.7 0.0 3.2 3 0 0 3 3 3 2 Lectin C-type domain FAM184 PF15665.5 PVD31935.1 - 0.79 9.5 23.0 0.18 11.5 13.1 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Laminin_II PF06009.12 PVD31935.1 - 5.1 7.1 18.7 0.12 12.4 1.7 3.3 3 0 0 3 3 3 0 Laminin Domain II Lectin_C PF00059.21 PVD31936.1 - 7.9e-10 39.4 0.1 5.9e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain HTH_1 PF00126.27 PVD31936.1 - 0.018 15.0 0.4 17 5.5 0.0 3.7 3 2 1 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family Laminin_II PF06009.12 PVD31936.1 - 0.024 14.6 3.1 0.024 14.6 3.1 3.2 2 1 1 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 PVD31936.1 - 1.2 8.7 15.8 2.6 7.5 15.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 PVD31936.1 - 4.8 7.6 15.7 1.3 9.4 7.9 2.4 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region PhaP_Bmeg PF09602.10 PVD31936.1 - 6.5 6.7 19.3 1.3 8.9 6.3 2.3 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Synaptobrevin PF00957.21 PVD31936.1 - 6.5 6.6 10.3 5.4 6.9 2.2 3.3 4 0 0 4 4 4 0 Synaptobrevin Imm3 PF14425.6 PVD31936.1 - 6.8 6.8 8.0 2.4 8.2 3.0 2.4 1 1 1 2 2 2 0 Immunity protein Imm3 Lectin_C PF00059.21 PVD31937.1 - 4.9e-08 33.7 0.4 2.5e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain CLZ PF16526.5 PVD31937.1 - 0.13 12.6 18.4 0.9 9.9 0.7 4.3 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SLT PF01464.20 PVD31937.1 - 0.31 10.7 2.1 6.2 6.5 0.1 2.7 3 0 0 3 3 2 0 Transglycosylase SLT domain Laminin_II PF06009.12 PVD31937.1 - 0.7 9.9 30.9 0.044 13.8 2.8 4.0 3 1 0 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 PVD31937.1 - 1 8.9 30.3 0.061 12.9 7.2 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Calici_MSP PF05752.11 PVD31937.1 - 1.1 9.1 5.5 2.3 8.0 0.2 2.6 3 0 0 3 3 3 0 Calicivirus minor structural protein Aida_N PF08910.10 PVD31937.1 - 1.2 9.6 8.8 7.3 7.1 2.4 3.1 1 1 1 2 2 2 0 Aida N-terminus DUF773 PF05600.12 PVD31937.1 - 1.7 7.3 25.0 0.056 12.2 2.1 3.2 2 1 1 3 3 3 0 CDK5 regulatory subunit-associated protein 3 Gp-FAR-1 PF05823.12 PVD31937.1 - 2 8.8 10.4 7 7.0 7.4 2.9 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HisKA_3 PF07730.13 PVD31937.1 - 3.7 8.1 8.2 40 4.8 0.1 3.7 3 0 0 3 3 3 0 Histidine kinase Snapin_Pallidin PF14712.6 PVD31937.1 - 6.1 7.3 33.3 0.028 14.8 4.7 4.9 2 2 2 4 4 4 0 Snapin/Pallidin Prominin PF05478.11 PVD31937.1 - 6.4 4.6 28.3 1.8 6.4 5.4 1.8 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 PVD31937.1 - 8.7 6.4 41.0 0.38 10.8 12.7 4.6 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 PVD31937.1 - 8.8 5.6 22.6 3.5e+02 0.3 22.4 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BLI1 PF17324.2 PVD31937.1 - 8.9 7.0 16.0 0.85 10.3 1.0 3.0 2 1 0 3 3 3 0 BLOC-1 interactor 1 Rab5-bind PF09311.11 PVD31937.1 - 9.6 5.5 31.9 5.2 6.4 7.5 2.3 1 1 0 2 2 2 0 Rabaptin-like protein Glyco_transf_7N PF13733.6 PVD31938.1 - 1e-16 60.8 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD31938.1 - 2.8e-13 49.3 0.0 5.9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Lectin_C PF00059.21 PVD31939.1 - 8e-10 39.4 0.2 1.4e-08 35.4 0.0 2.6 1 1 1 2 2 2 1 Lectin C-type domain Tropomyosin PF00261.20 PVD31939.1 - 0.029 13.7 0.4 0.057 12.8 0.2 1.5 1 1 0 1 1 1 0 Tropomyosin Nsp1_C PF05064.13 PVD31939.1 - 0.062 13.1 2.9 0.096 12.5 2.9 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Mt_ATP-synt_D PF05873.12 PVD31939.1 - 0.094 12.6 0.3 0.26 11.1 0.1 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) CENP-F_leu_zip PF10473.9 PVD31939.1 - 0.47 10.5 2.8 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 H_lectin PF09458.10 PVD31940.1 - 4.1e-18 65.3 0.7 1.3e-17 63.7 0.7 2.0 1 0 0 1 1 1 1 H-type lectin domain Baculo_PEP_C PF04513.12 PVD31940.1 - 0.013 15.5 39.5 0.24 11.4 6.9 4.1 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_1 PF00126.27 PVD31940.1 - 0.021 14.8 1.5 1.6 8.7 0.1 3.6 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family KNOX2 PF03791.13 PVD31940.1 - 2.3 7.8 6.3 7.1 6.2 0.3 3.3 2 1 1 3 3 3 0 KNOX2 domain Fibrinogen_C PF00147.18 PVD31941.1 - 5.2e-52 176.8 2.7 9.1e-42 143.3 0.7 2.7 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 PVD31941.1 - 2.6 7.9 49.9 0.069 13.0 3.7 4.8 2 2 2 4 4 4 0 Apolipoprotein A1/A4/E domain DUF2205 PF10224.9 PVD31941.1 - 6.9 6.7 11.4 1.1 9.4 0.2 3.9 3 0 0 3 3 3 0 Short coiled-coil protein Hydrolase_4 PF12146.8 PVD31942.1 - 3.2e-17 62.6 0.1 7.1e-11 41.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD31942.1 - 6.7e-13 48.9 0.1 3.9e-10 39.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 PVD31942.1 - 4.2e-11 42.1 0.2 0.016 13.9 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 PVD31942.1 - 1.3e-05 25.9 0.0 0.00013 22.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 PVD31942.1 - 0.00014 21.8 0.0 0.00051 20.0 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 PVD31942.1 - 0.00018 21.0 0.0 0.00041 19.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 PVD31942.1 - 0.00033 20.4 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 PVD31942.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein MeaB PF03308.16 PVD31942.1 - 0.0093 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Peptidase_S15 PF02129.18 PVD31942.1 - 0.011 15.3 0.0 0.073 12.6 0.0 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 PVD31942.1 - 0.012 15.5 0.6 0.025 14.5 0.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 PVD31942.1 - 0.018 14.6 0.0 0.21 11.1 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 PVD31942.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) SMN PF06003.12 PVD31943.1 - 5.1e-11 42.3 2.4 8.3e-11 41.6 2.3 1.3 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 PVD31943.1 - 2.9e-07 30.5 0.0 2.9e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 Tudor domain DUF4537 PF15057.6 PVD31943.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 PVD31943.1 - 0.02 15.0 2.1 0.027 14.6 0.1 2.0 2 0 0 2 2 2 0 SGF29 tudor-like domain DUF2316 PF10078.9 PVD31943.1 - 0.025 14.8 0.7 0.066 13.4 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) IL12 PF03039.14 PVD31943.1 - 0.036 13.4 0.1 0.055 12.8 0.1 1.5 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Tudor_2 PF18104.1 PVD31943.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF2730 PF10805.8 PVD31943.1 - 0.95 9.6 5.2 0.18 11.9 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) GST_N_4 PF17172.4 PVD31944.1 - 2.3e-24 86.0 0.0 4.1e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PVD31944.1 - 3e-22 78.2 0.0 5e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD31944.1 - 8.3e-13 48.2 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD31944.1 - 2e-05 24.7 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD31944.1 - 3.6e-05 23.9 0.0 5.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD31944.1 - 0.00015 22.1 0.0 0.0011 19.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PBP PF01161.20 PVD31945.1 - 4.4e-16 59.4 1.4 3.2e-12 46.9 0.3 2.3 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein Tmemb_cc2 PF10267.9 PVD31946.1 - 4.9e-127 424.4 25.2 1.1e-126 423.3 25.2 1.5 1 1 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Exonuc_VII_L PF02601.15 PVD31946.1 - 0.0063 16.1 23.6 0.1 12.1 5.0 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit ALMT PF11744.8 PVD31946.1 - 0.92 8.3 17.6 1.1 8.0 6.6 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4407 PF14362.6 PVD31946.1 - 1.7 7.9 17.3 3.4 6.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4735 PF15882.5 PVD31946.1 - 1.7 8.0 9.9 0.13 11.7 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) VAPB_antitox PF02697.14 PVD31946.1 - 3 8.7 9.3 1.1 10.1 0.9 3.3 2 2 1 3 3 3 0 Putative antitoxin Arv1 PF04161.13 PVD31946.1 - 5.5 7.1 7.0 26 4.9 7.0 2.1 1 1 0 1 1 1 0 Arv1-like family Prominin PF05478.11 PVD31946.1 - 6 4.7 19.5 0.27 9.2 4.9 2.2 2 0 0 2 2 2 0 Prominin DUF3584 PF12128.8 PVD31946.1 - 7.3 4.0 31.7 0.42 8.1 7.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Ldl_recept_a PF00057.18 PVD31952.1 - 7.9e-72 237.2 201.0 5.3e-11 42.5 11.0 13.2 12 1 1 13 13 13 12 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD31952.1 - 1.4e-39 133.7 30.9 2e-14 53.1 3.2 4.5 1 1 3 4 4 4 4 Leucine rich repeat 7tm_1 PF00001.21 PVD31952.1 - 1e-27 97.2 11.5 1.5e-27 96.6 11.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 PVD31952.1 - 5.8e-14 52.1 0.0 2.4e-09 37.2 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD31952.1 - 1.9e-13 50.4 23.4 0.00015 22.1 4.0 4.3 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD31952.1 - 6.8e-07 29.0 13.7 0.044 14.3 0.1 7.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 PVD31952.1 - 4.5e-05 23.0 2.5 0.00056 19.5 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat 7TM_GPCR_Srsx PF10320.9 PVD31952.1 - 0.00011 21.7 9.7 0.00022 20.7 9.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD31952.1 - 0.012 15.3 10.7 0.02 14.5 10.7 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Sulfotransfer_1 PF00685.27 PVD31953.1 - 3.3e-09 36.6 0.0 1.5e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD31953.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Pkinase PF00069.25 PVD31954.1 - 0.00045 19.7 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 PVD31955.1 - 2.8e-48 164.6 0.1 4e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD31955.1 - 3.7e-19 69.0 0.1 7.5e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Filament PF00038.21 PVD31956.1 - 0.0012 18.5 2.9 0.0018 17.9 2.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein Baculo_PEP_C PF04513.12 PVD31956.1 - 0.004 17.2 1.5 0.004 17.2 1.5 1.7 3 0 0 3 3 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.11 PVD31956.1 - 0.009 15.6 0.6 0.012 15.2 0.6 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Tmemb_cc2 PF10267.9 PVD31956.1 - 0.02 14.1 3.4 0.036 13.2 3.4 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Exonuc_VII_L PF02601.15 PVD31956.1 - 0.02 14.5 2.1 0.021 14.4 2.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tox-PL-2 PF15643.6 PVD31956.1 - 0.036 14.2 0.4 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Papain fold toxin 2 Snapin_Pallidin PF14712.6 PVD31956.1 - 0.038 14.4 2.8 0.038 14.4 2.8 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Phage_GPO PF05929.11 PVD31956.1 - 0.054 13.1 1.9 0.068 12.8 1.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HrpB7 PF09486.10 PVD31956.1 - 0.063 13.7 2.7 0.13 12.6 2.7 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Selenoprotein_S PF06936.11 PVD31956.1 - 0.065 13.0 1.5 0.081 12.7 0.5 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) HOOK PF05622.12 PVD31956.1 - 0.099 10.8 8.0 0.14 10.3 8.0 1.1 1 0 0 1 1 1 0 HOOK protein DUF1451 PF07295.11 PVD31956.1 - 0.099 12.7 3.8 0.11 12.6 0.6 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain TEX13 PF15186.6 PVD31956.1 - 0.11 12.2 3.2 0.19 11.4 3.2 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Fib_alpha PF08702.10 PVD31956.1 - 0.14 12.4 8.4 0.07 13.3 5.2 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 PVD31956.1 - 0.14 12.6 10.0 0.16 12.5 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Laminin_II PF06009.12 PVD31956.1 - 0.16 12.0 4.4 0.26 11.3 4.4 1.3 1 0 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.11 PVD31956.1 - 0.19 12.2 4.0 0.43 11.0 1.3 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cluap1 PF10234.9 PVD31956.1 - 0.21 10.9 5.9 0.3 10.4 5.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sipho_Gp157 PF05565.11 PVD31956.1 - 0.25 11.4 5.3 0.12 12.3 2.9 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1664 PF07889.12 PVD31956.1 - 0.35 10.9 5.0 0.86 9.7 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 PVD31956.1 - 0.41 10.7 7.1 1 9.4 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TMPIT PF07851.13 PVD31956.1 - 0.43 9.8 2.3 0.57 9.4 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 PVD31956.1 - 0.51 10.9 3.4 0.95 10.0 1.8 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.13 PVD31956.1 - 0.69 10.5 2.9 2.5 8.8 2.9 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 PVD31956.1 - 0.95 10.1 4.6 0.41 11.3 2.2 1.7 2 0 0 2 2 1 0 Initiation control protein YabA APG6_N PF17675.1 PVD31956.1 - 1 9.9 13.5 0.15 12.6 6.4 2.4 3 0 0 3 3 2 0 Apg6 coiled-coil region DivIC PF04977.15 PVD31956.1 - 1.3 8.8 6.6 0.56 10.0 3.1 2.0 1 1 1 2 2 2 0 Septum formation initiator DHR10 PF18595.1 PVD31956.1 - 2.9 8.0 11.9 0.36 10.9 7.8 1.6 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 PVD31956.1 - 3.9 8.1 10.9 26 5.4 4.2 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RNA_pol_I_A49 PF06870.12 PVD31957.1 - 9.5e-57 192.6 4.7 8.1e-54 183.0 0.6 2.0 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor RNA_pol_I_A49 PF06870.12 PVD31958.1 - 3.1e-67 227.1 4.3 3.5e-67 227.0 4.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor UBA_4 PF14555.6 PVD31959.1 - 3.3e-12 46.0 2.2 4.2e-12 45.7 0.4 2.0 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 PVD31959.1 - 4.3e-08 33.2 0.1 4e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 PVD31959.1 - 0.029 14.5 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like rRNA_processing PF08524.11 PVD31959.1 - 0.22 11.5 20.1 0.37 10.8 20.1 1.2 1 0 0 1 1 1 0 rRNA processing AAA_23 PF13476.6 PVD31959.1 - 0.62 10.5 10.1 1.2 9.6 10.1 1.5 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.16 PVD31959.1 - 2.7 7.3 10.1 4.1 6.7 10.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Caldesmon PF02029.15 PVD31959.1 - 2.7 6.7 23.2 3.8 6.2 23.2 1.1 1 0 0 1 1 1 0 Caldesmon Glyco_hydro_18 PF00704.28 PVD31960.1 - 5.9e-18 65.6 0.0 7.1e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sulfotransfer_2 PF03567.14 PVD31961.1 - 4e-22 79.4 4.3 3.9e-19 69.6 0.1 3.0 2 1 1 3 3 3 2 Sulfotransferase family DivIVA PF05103.13 PVD31961.1 - 0.043 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 DivIVA protein Sulfotransfer_2 PF03567.14 PVD31962.1 - 1.3e-20 74.4 4.1 3.6e-18 66.4 0.6 2.3 2 0 0 2 2 2 2 Sulfotransferase family DivIVA PF05103.13 PVD31962.1 - 0.044 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 DivIVA protein Ac76 PF05814.11 PVD31962.1 - 0.088 12.8 1.8 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Sulfotransfer_2 PF03567.14 PVD31963.1 - 5.7e-29 101.8 1.3 7.9e-26 91.5 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family DivIVA PF05103.13 PVD31963.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 DivIVA protein VHS PF00790.19 PVD31964.1 - 3.6e-36 124.1 0.0 2.9e-35 121.2 0.0 2.1 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 PVD31964.1 - 2.2e-15 56.0 0.1 3.9e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD31964.1 - 1.7e-10 40.4 0.0 3.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PVD31964.1 - 2.8e-10 39.9 0.1 6.3e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 PVD31964.1 - 0.0001 21.9 1.3 0.0001 21.9 1.3 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif Sigma54_CBD PF04963.13 PVD31964.1 - 0.002 18.0 0.1 0.0053 16.6 0.1 1.7 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Peptidase_C14 PF00656.22 PVD31965.1 - 1.9e-16 60.8 0.0 8.4e-16 58.7 0.0 2.1 2 1 0 2 2 2 1 Caspase domain CARD PF00619.21 PVD31965.1 - 8.2e-05 22.6 2.3 0.00035 20.5 0.7 2.5 2 0 0 2 2 2 1 Caspase recruitment domain Ras PF00071.22 PVD31966.1 - 2.5e-59 199.5 0.7 2.9e-59 199.3 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD31966.1 - 3.2e-34 117.7 0.6 4.6e-34 117.2 0.6 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD31966.1 - 3e-13 49.6 0.3 3.9e-13 49.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD31966.1 - 2e-07 31.1 0.1 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD31966.1 - 2.9e-06 27.0 0.8 9.4e-06 25.3 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD31966.1 - 5.3e-06 26.5 0.3 9.3e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD31966.1 - 1.1e-05 25.0 0.2 1.3e-05 24.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD31966.1 - 0.00045 19.7 0.1 0.00058 19.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PVD31966.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PVD31966.1 - 0.006 16.3 0.4 0.01 15.5 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD31966.1 - 0.0096 16.3 0.0 0.029 14.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 PVD31966.1 - 0.012 15.2 0.2 0.095 12.2 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Pox_A32 PF04665.12 PVD31966.1 - 0.025 14.1 0.0 0.062 12.8 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 PVD31966.1 - 0.047 13.0 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 PVD31966.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 PVD31966.1 - 0.097 12.3 0.6 2.9 7.4 0.1 2.6 1 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.11 PVD31966.1 - 0.097 12.4 0.0 3.7 7.2 0.1 2.3 1 1 1 2 2 2 0 Virulence-associated protein E PduV-EutP PF10662.9 PVD31966.1 - 0.11 12.2 0.4 1 9.1 0.4 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 PVD31966.1 - 0.13 12.2 0.4 0.27 11.1 0.3 1.6 1 1 0 1 1 1 0 NTPase AAA PF00004.29 PVD31966.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 PVD31966.1 - 0.3 10.2 1.5 0.86 8.7 0.3 2.2 1 1 1 2 2 2 0 G-protein alpha subunit GCS PF03074.16 PVD31967.1 - 4.3e-178 592.3 0.2 5.5e-178 591.9 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 PVD31967.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Laminin_EGF PF00053.24 PVD31968.1 - 0.12 12.5 3.8 0.3 11.3 3.8 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 PVD31968.1 - 0.18 12.2 6.7 0.39 11.1 6.7 1.6 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 PVD31969.1 - 0.16 12.2 4.4 0.34 11.1 4.4 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 PVD31969.1 - 0.85 10.0 11.7 1.8 9.0 11.7 1.6 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 PVD31969.1 - 3.8 7.9 8.4 8.7 6.8 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain ECH_1 PF00378.20 PVD31970.1 - 4.6e-37 127.7 0.1 6.7e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD31970.1 - 1.4e-14 54.4 0.2 6.9e-13 48.8 0.1 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MANEC PF07502.14 PVD31970.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.9 3 0 0 3 3 3 0 MANEC domain EGF_2 PF07974.13 PVD31971.1 - 0.05 14.0 3.4 0.13 12.7 3.4 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 PVD31971.1 - 0.12 12.7 5.9 0.49 10.7 5.9 2.1 1 1 0 1 1 1 0 EGF-like domain hEGF PF12661.7 PVD31971.1 - 8.4 7.2 8.9 0.69 10.6 3.5 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF Ribosomal_L5 PF00281.19 PVD31972.1 - 8.4e-23 80.5 0.0 3.2e-21 75.4 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 PVD31972.1 - 3.2e-22 78.5 0.0 5.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 PVD31972.1 - 0.053 13.2 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain tRNA_anti-like PF12869.7 PVD31972.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like NYD-SP28 PF14772.6 PVD31973.1 - 8.8e-29 99.5 15.7 8.8e-29 99.5 15.7 5.9 4 1 1 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 PVD31973.1 - 3.2e-19 68.8 3.8 3.2e-19 68.8 3.8 4.0 2 1 3 5 5 5 1 Sperm tail C-terminal domain GerPC PF10737.9 PVD31973.1 - 2.5 8.1 35.9 2 8.5 11.3 3.9 3 2 0 3 3 3 0 Spore germination protein GerPC T-box PF00907.22 PVD31974.1 - 2.2e-56 191.0 0.1 3.5e-56 190.4 0.1 1.3 1 0 0 1 1 1 1 T-box Lectin_C PF00059.21 PVD31975.1 - 7.5e-09 36.3 0.1 1.2e-08 35.6 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain NPP PF08384.10 PVD31975.1 - 0.029 14.4 0.2 0.066 13.3 0.2 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region AMP-binding PF00501.28 PVD31976.1 - 1.4e-91 307.2 0.0 1.7e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD31976.1 - 9.6e-18 64.9 0.5 2.2e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD31977.1 - 6.9e-92 308.2 0.0 8.4e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD31977.1 - 2.3e-16 60.5 0.4 7.2e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain G8 PF10162.9 PVD31977.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 G8 domain zf-C5HC2 PF02928.16 PVD31978.1 - 0.00024 21.4 0.3 1.3 9.4 0.0 2.9 2 0 0 2 2 2 2 C5HC2 zinc finger PEMT PF04191.13 PVD31978.1 - 0.018 15.4 0.1 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Phospholipid methyltransferase EHN PF06441.12 PVD31978.1 - 0.034 14.5 0.1 16 5.9 0.0 3.3 4 0 0 4 4 4 0 Epoxide hydrolase N terminus STELLO PF03385.17 PVD31979.1 - 1.1e-07 31.0 1.2 1.5e-07 30.6 1.2 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 PVD31981.1 - 2.4e-07 29.9 1.5 3.8e-07 29.3 1.5 1.3 1 1 0 1 1 1 1 STELLO glycosyltransferases zf-C5HC2 PF02928.16 PVD31982.1 - 0.001 19.4 2.8 1 9.8 0.1 3.4 3 0 0 3 3 3 2 C5HC2 zinc finger Fibrillin_U_N PF18193.1 PVD31982.1 - 0.0016 18.5 0.3 1.4 9.0 0.0 4.0 4 0 0 4 4 4 1 Fibrillin 1 unique N-terminal domain Galactosyl_T PF01762.21 PVD31982.1 - 0.0029 17.5 0.7 20 4.9 0.0 3.5 3 0 0 3 3 3 2 Galactosyltransferase EHN PF06441.12 PVD31982.1 - 0.0031 17.9 0.0 9.2 6.7 0.0 3.4 3 0 0 3 3 3 2 Epoxide hydrolase N terminus PEMT PF04191.13 PVD31982.1 - 0.02 15.3 0.8 31 5.0 0.1 3.6 3 0 0 3 3 3 0 Phospholipid methyltransferase STELLO PF03385.17 PVD31983.1 - 7.6e-05 21.7 0.7 0.00011 21.1 0.7 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 PVD31984.1 - 4.4e-05 22.5 0.5 6e-05 22.0 0.5 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 PVD31985.1 - 0.00034 19.6 1.3 0.00045 19.2 1.3 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 PVD31986.1 - 2.7e-08 33.1 0.1 3.7e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases SCAN PF02023.17 PVD31987.1 - 5.5e-13 48.5 0.2 1.1e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 PVD31987.1 - 1.3e-06 28.2 0.4 2.5e-06 27.3 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD31987.1 - 0.078 12.8 0.2 0.078 12.8 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF4246 PF14033.6 PVD31987.1 - 0.26 10.3 2.7 0.49 9.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) GNAT_acetyltr_2 PF13718.6 PVD31987.1 - 2 7.8 5.6 3.7 6.9 5.6 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 EIF4E-T PF10477.9 PVD31987.1 - 5 5.8 22.5 9.6 4.9 22.5 1.4 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E STELLO PF03385.17 PVD31988.1 - 6.9e-05 21.8 0.2 8.6e-05 21.5 0.2 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases MAP17 PF15807.5 PVD31989.1 - 0.00051 20.3 3.7 0.00051 20.3 3.7 2.3 1 1 1 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PWI PF01480.17 PVD31989.1 - 0.002 18.4 1.3 0.0088 16.3 0.1 2.2 1 1 1 2 2 2 1 PWI domain Presenilin PF01080.17 PVD31989.1 - 1.1 7.9 8.3 1.3 7.7 8.3 1.3 1 0 0 1 1 1 0 Presenilin Ureide_permease PF07168.11 PVD31989.1 - 1.9 7.1 2.8 0.92 8.2 0.2 1.7 2 0 0 2 2 2 0 Ureide permease Borrelia_P83 PF05262.11 PVD31989.1 - 2.4 6.5 19.3 4 5.8 19.3 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein BPL_LplA_LipB PF03099.19 PVD31990.1 - 0.034 14.1 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family NmrA PF05368.13 PVD31991.1 - 2.8e-27 95.8 0.0 4.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PVD31991.1 - 1.5e-11 44.5 0.0 3.3e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PVD31991.1 - 0.00042 19.4 0.1 0.00096 18.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PVD31991.1 - 0.0069 15.9 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PIG-P PF08510.12 PVD31991.1 - 0.074 13.0 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 PIG-P DUF4034 PF13226.6 PVD31991.1 - 0.19 11.0 0.7 0.39 10.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) zf-C2HC_2 PF13913.6 PVD31992.1 - 7.7e-06 25.7 19.9 1.7e-05 24.6 2.7 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type ShK PF01549.24 PVD31992.1 - 0.00081 19.9 59.0 0.0014 19.1 4.7 6.3 5 0 0 5 5 5 3 ShK domain-like zf-CHCC PF10276.9 PVD31992.1 - 0.051 13.7 0.1 0.051 13.7 0.1 3.6 5 0 0 5 5 5 0 Zinc-finger domain zf-C2H2_6 PF13912.6 PVD31992.1 - 0.054 13.5 6.0 1.5 8.9 0.3 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 PVD31992.1 - 2 8.9 8.9 1 9.9 0.3 4.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Myotub-related PF06602.14 PVD31993.1 - 2.1e-130 434.8 0.3 3e-130 434.3 0.3 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 PVD31993.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 GRAM domain zf-C2H2_4 PF13894.6 PVD31994.1 - 5.5e-05 23.7 41.9 0.22 12.4 0.4 7.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD31994.1 - 0.0018 18.6 39.5 0.11 13.0 0.3 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type Ribosomal_60s PF00428.19 PVD31994.1 - 0.25 11.9 2.8 18 6.0 4.8 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_6 PF13912.6 PVD31994.1 - 7.8 6.6 11.4 34 4.6 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger STT3 PF02516.14 PVD31995.1 - 3.5e-146 488.0 42.2 1.8e-144 482.3 38.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Kelch_4 PF13418.6 PVD31995.1 - 7.5e-18 64.3 5.2 3.7e-05 23.7 0.0 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD31995.1 - 7.1e-13 47.9 7.7 8.7e-05 22.0 0.3 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PVD31995.1 - 1.5e-12 47.5 10.4 0.00055 20.1 0.1 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD31995.1 - 1.2e-11 44.1 8.3 0.015 15.3 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PVD31995.1 - 2.2e-08 33.9 4.3 2 8.5 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 PVD31995.1 - 2.5e-08 33.9 10.6 0.051 13.9 0.0 5.7 5 1 1 6 6 6 3 Kelch motif PMT_2 PF13231.6 PVD31995.1 - 0.00014 22.1 14.5 0.00014 22.1 14.5 2.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TRAPPC9-Trs120 PF08626.11 PVD31996.1 - 2.3e-43 147.9 0.0 6.8e-19 66.8 0.0 4.7 3 2 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit BNIP2 PF12496.8 PVD31997.1 - 1.2 9.5 8.1 9.6 6.6 3.4 2.3 1 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PLAC8 PF04749.17 PVD31998.1 - 3.3e-09 37.6 2.9 4.4e-09 37.2 2.9 1.3 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 PVD32000.1 - 1.1e-08 36.0 7.1 1.7e-08 35.4 7.1 1.4 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 PVD32001.1 - 3.1e-10 40.9 11.8 1e-08 36.0 5.0 2.2 2 0 0 2 2 2 2 PLAC8 family TIR_2 PF13676.6 PVD32002.1 - 2.3e-20 73.3 0.0 6.9e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 TIR domain V-ATPase_H_N PF03224.14 PVD32002.1 - 2.3e-06 27.1 1.5 4.2e-06 26.3 1.5 1.4 1 0 0 1 1 1 1 V-ATPase subunit H Adaptin_N PF01602.20 PVD32002.1 - 7.7e-06 24.7 0.4 1.5e-05 23.8 0.4 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Arm PF00514.23 PVD32002.1 - 0.058 13.5 0.7 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Nudix_hydro PF18290.1 PVD32002.1 - 0.069 13.1 0.3 0.6 10.1 0.0 2.7 3 0 0 3 3 3 0 Nudix hydrolase domain TIR_2 PF13676.6 PVD32003.1 - 1.9e-27 96.2 0.0 5.9e-27 94.6 0.0 1.9 1 0 0 1 1 1 1 TIR domain V-ATPase_H_N PF03224.14 PVD32003.1 - 3.3e-06 26.6 1.9 6.5e-06 25.7 1.9 1.5 1 0 0 1 1 1 1 V-ATPase subunit H Adaptin_N PF01602.20 PVD32003.1 - 2.1e-05 23.3 0.5 4.2e-05 22.3 0.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region TIR PF01582.20 PVD32003.1 - 0.002 18.0 1.1 0.0061 16.4 0.0 2.4 2 0 0 2 2 2 1 TIR domain Saccharop_dh_N PF04455.12 PVD32003.1 - 0.045 14.2 0.5 52 4.3 0.0 3.7 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region Arm PF00514.23 PVD32003.1 - 0.091 12.8 0.9 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF4653 PF15546.6 PVD32004.1 - 0.0032 17.1 2.3 0.0039 16.9 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) DUF4611 PF15387.6 PVD32005.1 - 0.033 14.4 0.7 0.033 14.4 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) 7tm_1 PF00001.21 PVD32010.1 - 2.1e-09 37.1 1.3 3.5e-09 36.4 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0542 PF15086.6 PVD32010.1 - 0.13 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Sulfotransfer_1 PF00685.27 PVD32012.1 - 4.9e-08 32.8 0.0 9.4e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32012.1 - 6.8e-05 23.4 0.0 9.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Methyltransf_31 PF13847.6 PVD32013.1 - 3.5e-32 111.3 0.0 5.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD32013.1 - 6.1e-18 65.3 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD32013.1 - 3.6e-17 62.8 0.0 7.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD32013.1 - 4.2e-15 55.7 0.0 7.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PVD32013.1 - 1.2e-10 41.5 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD32013.1 - 3.2e-10 40.6 0.0 7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD32013.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PVD32013.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD32013.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 PVD32013.1 - 0.03 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_8 PF05148.15 PVD32013.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase GCD14 PF08704.10 PVD32013.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PVD32014.1 - 1.3e-16 60.7 0.0 2.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD32014.1 - 3.7e-10 40.4 0.0 1.4e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD32014.1 - 4.8e-06 27.1 0.0 5.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD32014.1 - 8.5e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PVD32014.1 - 9.6e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 PVD32014.1 - 0.0037 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 PVD32014.1 - 0.019 15.7 0.0 0.03 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PVD32014.1 - 0.02 14.7 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 PVD32014.1 - 0.11 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_11 PF01531.16 PVD32015.1 - 1.2e-31 110.0 0.1 1.7e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32015.1 - 0.0048 16.6 0.5 0.0072 16.1 0.5 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_S9_N PF02897.15 PVD32016.1 - 2.9e-145 484.2 0.4 3.6e-145 483.9 0.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PVD32016.1 - 1.3e-65 220.8 0.0 2.8e-65 219.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family PTH2 PF01981.16 PVD32017.1 - 8.7e-24 84.1 0.1 9.8e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PDDEXK_3 PF13366.6 PVD32017.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Peptidase_M3_N PF08439.10 PVD32017.1 - 0.096 13.0 1.0 0.15 12.3 0.2 1.7 2 0 0 2 2 2 0 Oligopeptidase F KilA-N PF04383.13 PVD32017.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 KilA-N domain Glyco_transf_11 PF01531.16 PVD32019.1 - 4.6e-29 101.6 0.2 6.2e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32019.1 - 0.0024 17.6 0.4 0.004 16.9 0.4 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_S9_N PF02897.15 PVD32020.1 - 1.9e-144 481.5 0.3 2.3e-144 481.2 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PVD32020.1 - 4.3e-45 153.8 0.0 1e-44 152.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family PTH2 PF01981.16 PVD32021.1 - 8.1e-24 84.2 0.1 9.1e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 USP7_ICP0_bdg PF12436.8 PVD32021.1 - 0.037 13.3 0.7 0.043 13.1 0.7 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Peptidase_M3_N PF08439.10 PVD32021.1 - 0.062 13.6 1.1 0.095 13.0 0.2 1.7 2 0 0 2 2 2 0 Oligopeptidase F PDDEXK_3 PF13366.6 PVD32021.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily KilA-N PF04383.13 PVD32021.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 KilA-N domain ADH_zinc_N PF00107.26 PVD32021.1 - 0.14 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase I-set PF07679.16 PVD32022.1 - 1.2e-16 60.5 0.0 2.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD32022.1 - 5.3e-12 46.2 0.0 5e-11 43.1 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 PVD32022.1 - 6.4e-07 29.6 0.0 3.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD32022.1 - 0.00011 22.3 0.1 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain PKD_3 PF16820.5 PVD32022.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 PKD-like domain V-set PF07686.17 PVD32022.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin V-set domain HECT PF00632.25 PVD32023.1 - 8.6e-62 209.4 0.0 1.6e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 PVD32023.1 - 1.6e-30 104.6 3.5 1.6e-30 104.6 3.5 2.2 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD PABP PF00658.18 PVD32023.1 - 1.5e-20 73.2 0.1 3.5e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-UBR PF02207.20 PVD32023.1 - 0.0061 16.7 22.1 0.014 15.5 22.1 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) IATP PF04568.12 PVD32024.1 - 7.5e-27 93.6 0.8 9.8e-27 93.3 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 7TM_GPCR_Srw PF10324.9 PVD32025.1 - 9.5e-11 41.5 10.6 2e-10 40.5 10.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD32025.1 - 8.7e-09 35.1 6.0 1.3e-08 34.5 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD32025.1 - 0.0008 19.1 16.7 0.0021 17.7 16.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD32025.1 - 0.0099 15.9 2.7 0.0099 15.9 2.7 1.8 1 1 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srw PF10324.9 PVD32026.1 - 1e-08 34.9 17.8 2.6e-08 33.5 17.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD32026.1 - 0.00013 21.4 11.3 0.00019 20.9 11.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 PVD32026.1 - 0.00073 19.5 2.0 0.00073 19.5 2.0 2.2 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa Monooxygenase_B PF04744.12 PVD32026.1 - 0.0066 15.3 0.3 0.012 14.5 0.1 1.5 2 0 0 2 2 2 1 Monooxygenase subunit B protein LPAM_1 PF08139.12 PVD32026.1 - 2.2 9.0 6.3 0.47 11.1 0.8 3.0 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site 7TM_GPCR_Srw PF10324.9 PVD32027.1 - 2.3e-07 30.4 5.0 0.0018 17.6 1.5 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Ost4 PF10215.9 PVD32027.1 - 0.12 12.2 3.0 0.43 10.5 3.0 2.0 1 0 0 1 1 1 0 Oligosaccaryltransferase 7TM_GPCR_Srx PF10328.9 PVD32028.1 - 1.2e-09 38.2 22.4 0.00041 20.1 4.5 4.3 3 1 1 4 4 4 3 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD32028.1 - 0.0002 20.8 20.4 0.014 14.7 3.0 3.8 4 1 0 4 4 4 3 7 transmembrane receptor (rhodopsin family) LPAM_1 PF08139.12 PVD32028.1 - 0.0017 18.8 7.5 0.34 11.5 0.8 3.3 2 0 0 2 2 2 2 Prokaryotic membrane lipoprotein lipid attachment site Serpentine_r_xa PF03383.15 PVD32028.1 - 0.0087 16.0 5.7 0.026 14.5 1.8 2.8 2 0 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa DUF5392 PF17370.2 PVD32028.1 - 0.082 13.0 11.3 4.6 7.3 0.0 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5392) Adeno_shaft PF00608.17 PVD32028.1 - 0.43 10.5 5.8 3.7 7.5 0.1 2.8 3 0 0 3 3 3 0 Adenoviral fibre protein (repeat/shaft region) DUF1835 PF08874.10 PVD32031.1 - 0.024 14.8 0.0 6.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) EF-hand_1 PF00036.32 PVD32033.1 - 7.9e-33 109.6 17.2 4.7e-08 32.0 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD32033.1 - 2e-26 92.2 6.9 1.4e-12 47.8 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD32033.1 - 3.4e-26 88.9 6.5 8.1e-07 28.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PVD32033.1 - 2.4e-23 80.5 9.7 1.3e-06 27.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PVD32033.1 - 2.6e-20 72.0 15.0 3.4e-11 42.8 0.7 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PVD32033.1 - 1.5e-09 38.0 0.2 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD32033.1 - 5e-07 30.0 1.5 0.002 18.4 0.2 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD32033.1 - 6.1e-07 29.4 5.4 0.013 15.4 0.5 3.2 2 2 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PVD32033.1 - 3.8e-06 27.0 0.5 1.8 8.8 0.0 3.7 3 1 1 4 4 4 3 Dockerin type I domain Caleosin PF05042.13 PVD32033.1 - 0.056 13.4 0.8 0.52 10.2 0.0 2.5 1 1 1 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 PVD32033.1 - 0.072 14.0 0.0 2.9 8.8 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 PVD32033.1 - 0.11 12.9 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PVD32034.1 - 1.1e-29 102.7 10.1 1.5e-14 54.1 2.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD32034.1 - 2.8e-29 98.4 17.8 7.5e-10 37.6 1.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 PVD32034.1 - 5.9e-23 79.3 15.9 1.9e-08 33.4 1.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD32034.1 - 6.4e-22 75.6 15.7 3.6e-08 32.7 1.3 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PVD32034.1 - 3e-16 59.0 19.2 2.6e-06 27.2 3.8 4.3 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD32034.1 - 1.6e-09 38.1 0.7 0.00079 19.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PVD32034.1 - 2.3e-07 31.0 0.5 0.0057 17.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PVD32034.1 - 6.7e-06 26.0 11.0 0.14 12.1 0.9 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand Phage_TAC_12 PF12363.8 PVD32034.1 - 0.04 14.3 2.4 1.5 9.3 0.2 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Asp-B-Hydro_N PF05279.11 PVD32034.1 - 0.042 13.9 4.9 0.043 13.9 3.5 1.7 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPF0154 PF03672.13 PVD32034.1 - 0.045 13.8 0.2 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Toprim_2 PF13155.6 PVD32034.1 - 0.048 14.1 4.1 1.4 9.4 0.5 2.9 1 1 2 3 3 3 0 Toprim-like Excalibur PF05901.11 PVD32034.1 - 0.072 13.7 5.9 40 4.9 0.0 4.3 4 0 0 4 4 4 0 Excalibur calcium-binding domain T3SS_needle_reg PF09025.10 PVD32034.1 - 0.088 12.8 0.4 2.6 8.0 0.0 2.3 1 1 1 2 2 2 0 YopR, type III needle-polymerisation regulator DUF1398 PF07166.11 PVD32034.1 - 0.11 12.5 0.1 1.5 8.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) EF-hand_11 PF08976.11 PVD32034.1 - 0.15 12.9 0.1 8 7.4 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain S_100 PF01023.19 PVD32034.1 - 0.25 11.1 5.6 23 4.8 0.1 3.5 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain EF-hand_14 PF17959.1 PVD32034.1 - 0.25 11.7 1.2 11 6.4 0.2 2.3 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 PVD32034.1 - 0.3 10.8 3.6 0.35 10.6 0.2 2.3 2 1 1 3 3 3 0 SurA N-terminal domain DUF496 PF04363.12 PVD32034.1 - 0.37 10.8 5.9 3.9 7.6 1.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF496) DUF5109 PF17134.4 PVD32034.1 - 0.57 10.1 2.7 28 4.7 0.2 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5109) RNase_H PF00075.24 PVD32035.1 - 5.2e-05 23.4 0.2 9.2e-05 22.7 0.2 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 PVD32035.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Glyco_transf_64 PF09258.10 PVD32037.1 - 3.1e-90 301.8 0.0 4.5e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 PVD32037.1 - 2.2e-29 102.6 0.0 4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Exostosin family MscS_porin PF12795.7 PVD32037.1 - 0.0031 17.1 0.4 0.005 16.4 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain ZapB PF06005.12 PVD32037.1 - 0.018 15.4 1.4 0.048 14.1 1.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB PspA_IM30 PF04012.12 PVD32037.1 - 0.045 13.3 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family DMPK_coil PF08826.10 PVD32037.1 - 0.069 13.3 0.5 0.2 11.8 0.5 1.8 1 0 0 1 1 1 0 DMPK coiled coil domain like FPP PF05911.11 PVD32037.1 - 0.19 9.9 1.7 0.28 9.3 1.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Yuri_gagarin PF15934.5 PVD32037.1 - 0.2 11.4 4.6 3.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Yuri gagarin Spc7 PF08317.11 PVD32037.1 - 0.25 10.2 2.1 0.44 9.4 2.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 PVD32037.1 - 0.39 10.9 3.0 0.72 10.1 3.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 PVD32037.1 - 0.88 8.6 3.6 0.54 9.3 1.5 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 PVD32037.1 - 5.4 7.6 9.8 0.074 13.6 2.0 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Haemocyan_bet_s PF14830.6 PVD32038.1 - 2e-76 252.6 0.0 1.4e-38 131.0 0.0 3.4 3 0 0 3 3 3 3 Haemocyanin beta-sandwich Tyrosinase PF00264.20 PVD32038.1 - 2e-54 185.2 7.8 4.8e-16 59.7 0.5 4.3 2 2 2 4 4 4 4 Common central domain of tyrosinase Tyrosinase PF00264.20 PVD32039.1 - 4.1e-63 213.6 18.8 5.7e-31 108.5 8.2 3.7 2 2 0 2 2 2 2 Common central domain of tyrosinase Haemocyan_bet_s PF14830.6 PVD32039.1 - 1.4e-53 179.2 0.0 2.8e-38 130.0 0.0 2.5 2 0 0 2 2 2 2 Haemocyanin beta-sandwich Tyrosinase PF00264.20 PVD32040.1 - 4.3e-104 347.7 35.0 2.6e-32 112.9 6.4 7.3 4 3 1 5 5 5 5 Common central domain of tyrosinase Haemocyan_bet_s PF14830.6 PVD32040.1 - 2.1e-87 287.8 0.0 1.7e-31 108.3 0.0 3.6 3 0 0 3 3 3 3 Haemocyanin beta-sandwich DUF5053 PF16476.5 PVD32040.1 - 0.02 14.6 0.2 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) ATP1G1_PLM_MAT8 PF02038.16 PVD32040.1 - 4.8 6.7 5.8 1.2 8.7 0.2 2.7 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family DUF4913 PF16259.5 PVD32040.1 - 5.7 7.1 7.3 56 3.9 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4913) Tyrosinase PF00264.20 PVD32041.1 - 3.2e-13 50.5 0.0 3.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase Gtr1_RagA PF04670.12 PVD32042.1 - 9.4e-74 247.6 1.0 1.4e-73 247.1 1.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 PVD32042.1 - 1.4e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PVD32042.1 - 0.00052 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PVD32042.1 - 0.00059 20.0 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD32042.1 - 0.001 18.7 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PVD32042.1 - 0.0027 17.8 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD32042.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain LNS2 PF08235.13 PVD32043.1 - 3.7e-94 314.4 0.0 5.9e-94 313.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 PVD32043.1 - 1e-41 141.0 0.2 3.3e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 PVD32043.1 - 2.3e-28 98.3 0.0 7.7e-28 96.6 0.0 2.0 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 PVD32043.1 - 0.06 14.2 0.0 0.06 14.2 0.0 3.8 4 0 0 4 4 4 0 Putative WW-binding domain and destruction box NAPRTase_N PF17767.1 PVD32044.1 - 7.8e-41 139.4 0.1 2.3e-40 137.8 0.1 1.9 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 PVD32044.1 - 3e-37 127.4 0.1 5.4e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 PVD32044.1 - 1.2e-08 34.9 0.0 2.6e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 PVD32044.1 - 0.012 15.7 0.0 0.033 14.2 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Sushi PF00084.20 PVD32045.1 - 1.3e-06 28.9 2.6 1.3e-06 28.9 2.6 2.6 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) DSPc PF00782.20 PVD32046.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD32046.1 - 5.7e-07 29.4 0.0 7.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD32046.1 - 0.047 13.7 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1126 PF06565.12 PVD32047.1 - 5.5e-101 331.5 1.8 1.4e-35 121.3 0.2 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 PVD32047.1 - 2.2e-05 24.8 0.0 4.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD32047.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair 4F5 PF04419.14 PVD32049.1 - 3.5e-10 40.6 9.8 5e-10 40.1 9.8 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 PVD32049.1 - 0.0036 17.7 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type GAGA PF09237.11 PVD32049.1 - 0.0044 16.8 1.1 0.0044 16.8 1.1 1.4 1 1 0 1 1 1 1 GAGA factor zf-C2H2_jaz PF12171.8 PVD32049.1 - 0.0058 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD32049.1 - 0.0059 17.4 1.2 0.011 16.5 1.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 PVD32049.1 - 0.0063 16.8 0.9 0.0097 16.2 0.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 PVD32049.1 - 0.021 13.4 0.7 0.02 13.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf_C2H2_10 PF18414.1 PVD32049.1 - 0.029 13.9 1.1 0.047 13.2 1.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-met2 PF12907.7 PVD32049.1 - 0.056 13.6 5.0 0.34 11.1 5.0 2.2 1 1 0 1 1 1 0 Zinc-binding DUF1644 PF07800.12 PVD32049.1 - 0.064 13.3 3.0 0.1 12.7 3.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DTC PF18102.1 PVD32050.1 - 4.2e-60 201.7 0.0 6.8e-60 201.0 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_UBOX PF13445.6 PVD32050.1 - 1.2e-10 41.3 9.7 1e-08 35.1 9.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD32050.1 - 2.6e-10 39.9 13.7 2.6e-10 39.9 13.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD32050.1 - 2.1e-08 34.3 12.1 2.1e-08 34.3 12.1 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 PVD32050.1 - 2.6e-08 33.6 13.2 2.6e-08 33.6 13.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD32050.1 - 1.6e-06 27.9 8.0 1.6e-06 27.9 8.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PVD32050.1 - 2.2e-06 27.4 2.3 2.2e-06 27.4 2.3 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Macro PF01661.21 PVD32050.1 - 3.4e-06 27.1 0.0 7.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Macro domain zf-C3HC4_4 PF15227.6 PVD32050.1 - 5e-06 26.6 9.9 5e-06 26.6 9.9 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PVD32050.1 - 0.00044 20.5 8.9 0.00044 20.5 8.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD32050.1 - 0.00087 19.2 12.3 0.00087 19.2 12.3 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.8 PVD32050.1 - 0.0033 17.2 10.2 0.0091 15.8 10.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 PVD32050.1 - 0.0088 16.1 5.0 0.044 13.9 5.0 2.2 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-RING_11 PF17123.5 PVD32050.1 - 0.025 14.3 6.6 0.029 14.1 4.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 PVD32050.1 - 0.14 11.9 13.5 0.12 12.2 9.8 2.8 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 PVD32050.1 - 0.17 11.8 4.6 0.43 10.5 4.3 1.7 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) zf-MIZ PF02891.20 PVD32050.1 - 0.21 11.4 8.8 0.6 9.9 8.8 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 PVD32050.1 - 0.34 10.8 19.5 0.98 9.3 12.5 3.8 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 PVD32050.1 - 1.9 8.6 8.2 3.9 7.6 7.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) MFS_1 PF07690.16 PVD32051.1 - 2.8e-23 82.4 28.3 1.2e-22 80.3 28.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 PVD32051.1 - 0.012 14.1 1.6 0.014 13.8 1.6 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector ATPase_gene1 PF09527.10 PVD32051.1 - 0.017 15.2 1.9 0.017 15.2 1.9 3.1 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter MFS_2 PF13347.6 PVD32051.1 - 1.2 7.6 21.0 0.13 10.8 8.1 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein PhyH PF05721.13 PVD32052.1 - 5.4e-27 95.4 0.1 6.6e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Reprolysin PF01421.19 PVD32054.1 - 5.8e-06 26.4 0.1 1.4e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD32054.1 - 0.00059 20.0 2.4 0.00059 20.0 2.4 3.5 2 2 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD32054.1 - 0.0021 18.0 2.1 0.0088 16.0 1.7 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD32054.1 - 0.0051 17.3 0.6 0.016 15.7 0.6 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SP_C-Propep PF08999.10 PVD32054.1 - 0.015 15.1 1.5 0.12 12.1 1.2 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide HMGL-like PF00682.19 PVD32055.1 - 5.5e-60 203.2 0.0 8.7e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Reprolysin_5 PF13688.6 PVD32055.1 - 3.9e-12 46.7 0.4 8.4e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD32055.1 - 2.7e-09 37.6 0.3 8.1e-09 36.1 0.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD32055.1 - 2e-08 34.4 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD32055.1 - 8.4e-06 25.6 1.4 1.6e-05 24.7 1.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD32055.1 - 0.019 14.8 0.3 0.035 14.0 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ax_dynein_light PF10211.9 PVD32056.1 - 1.1e-94 315.6 15.1 1.4e-94 315.3 15.1 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 PVD32056.1 - 0.00063 18.6 8.9 0.00063 18.6 8.9 1.5 2 0 0 2 2 2 1 RIB43A Mei5 PF10376.9 PVD32056.1 - 0.00074 19.4 6.0 0.0012 18.8 6.0 1.4 1 0 0 1 1 1 1 Double-strand recombination repair protein Syntaxin-6_N PF09177.11 PVD32056.1 - 0.0021 18.5 7.8 0.0021 18.5 7.8 1.7 2 0 0 2 2 1 1 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 PVD32056.1 - 0.0064 16.7 10.7 0.0064 16.7 10.7 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 DUF4600 PF15372.6 PVD32056.1 - 0.011 16.2 7.6 0.027 14.9 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) HALZ PF02183.18 PVD32056.1 - 0.013 15.7 2.7 0.013 15.7 2.7 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper FapA PF03961.13 PVD32056.1 - 0.014 14.0 3.6 0.019 13.6 3.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TSNAXIP1_N PF15739.5 PVD32056.1 - 0.017 15.5 4.0 0.017 15.5 4.0 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus End3 PF12761.7 PVD32056.1 - 0.017 15.3 6.1 0.017 15.3 6.1 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 BshC PF10079.9 PVD32056.1 - 0.034 12.9 6.5 0.053 12.3 6.5 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC APG6_N PF17675.1 PVD32056.1 - 0.065 13.8 20.9 0.29 11.6 21.3 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4482 PF14818.6 PVD32056.1 - 0.1 13.5 14.5 0.14 13.1 12.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Spc7 PF08317.11 PVD32056.1 - 0.11 11.4 10.5 0.24 10.3 10.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3810 PF12725.7 PVD32056.1 - 0.16 11.3 0.6 0.2 10.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Spc24 PF08286.11 PVD32056.1 - 0.27 11.5 11.5 0.13 12.5 9.0 1.8 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 TolA_bind_tri PF16331.5 PVD32056.1 - 0.33 11.0 11.9 0.046 13.8 5.4 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF3450 PF11932.8 PVD32056.1 - 0.39 10.0 14.3 0.06 12.6 10.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.24 PVD32056.1 - 0.4 10.6 3.8 0.64 9.9 3.8 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Aconitase_C PF00694.19 PVD32056.1 - 0.49 10.7 2.1 0.97 9.8 2.1 1.4 1 0 0 1 1 1 0 Aconitase C-terminal domain Raptor_N PF14538.6 PVD32056.1 - 0.5 10.3 3.5 30 4.6 2.6 2.8 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain RecG_N PF17190.4 PVD32056.1 - 0.69 10.7 6.8 3.1 8.6 6.4 2.0 2 0 0 2 2 2 0 RecG N-terminal helical domain GrpE PF01025.19 PVD32056.1 - 0.78 9.4 12.3 1.9 8.1 12.3 1.6 1 0 0 1 1 1 0 GrpE FlaC_arch PF05377.11 PVD32056.1 - 0.98 9.9 6.4 1.5 9.2 2.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 PVD32056.1 - 1.1 9.3 5.3 2.5 8.2 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 PVD32056.1 - 1.3 10.0 15.1 0.83 10.6 12.4 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 PVD32056.1 - 1.4 8.2 10.8 2.7 7.3 10.8 1.4 1 0 0 1 1 1 0 FAM76 protein Remorin_C PF03763.13 PVD32056.1 - 1.4 8.8 13.8 3.1 7.7 13.8 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region ADIP PF11559.8 PVD32056.1 - 1.6 8.8 15.9 3.8 7.6 15.9 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 PVD32056.1 - 1.9 7.7 6.6 2.8 7.1 6.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 PVD32056.1 - 1.9 6.3 5.8 2.6 5.9 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACCA PF03255.14 PVD32056.1 - 3.3 7.6 9.5 1.4 8.8 6.0 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_lysis PF03245.13 PVD32056.1 - 3.5 7.8 12.2 0.86 9.7 8.7 1.7 2 0 0 2 2 1 0 Bacteriophage Rz lysis protein MCU PF04678.13 PVD32056.1 - 3.6 7.6 6.8 5.3 7.1 5.2 1.9 2 1 0 2 2 2 0 Mitochondrial calcium uniporter DUF4337 PF14235.6 PVD32056.1 - 4.1 7.5 6.9 7.3 6.7 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF5320 PF17253.2 PVD32056.1 - 4.1 8.5 8.2 1.5 9.9 2.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 PVD32056.1 - 5 7.0 21.2 0.1 12.4 8.4 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF724 PF05266.14 PVD32056.1 - 7.4 6.3 14.1 3.2 7.5 11.8 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF724) GPS2_interact PF15784.5 PVD32056.1 - 8.2 6.9 13.5 32 5.0 13.5 2.1 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TPR_14 PF13428.6 PVD32057.1 - 7.1e-10 38.9 1.1 0.014 16.2 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD32057.1 - 4.2e-08 33.6 2.4 0.45 11.1 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD32057.1 - 1.1e-06 29.2 0.5 0.14 12.8 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD32057.1 - 5.5e-06 26.1 6.8 0.57 10.4 0.0 4.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32057.1 - 0.00017 21.5 1.9 0.16 12.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF386 PF04074.12 PVD32057.1 - 0.0011 18.9 0.1 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 YhcH/YjgK/YiaL TPR_12 PF13424.6 PVD32057.1 - 0.0024 18.1 0.4 0.098 13.0 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD32057.1 - 0.0046 16.6 2.3 0.016 14.9 0.1 2.8 3 0 0 3 3 3 1 TPR repeat HrpB1_HrpK PF09613.10 PVD32057.1 - 0.037 13.7 1.8 0.23 11.1 0.4 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) MCCD1 PF15707.5 PVD32057.1 - 0.054 14.0 3.0 7.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 TPR_6 PF13174.6 PVD32057.1 - 0.082 13.6 3.5 72 4.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PVD32057.1 - 0.089 13.2 5.5 5.2 7.5 0.2 3.0 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation DUF4724 PF15852.5 PVD32057.1 - 0.13 12.7 0.1 0.31 11.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4724) TPR_1 PF00515.28 PVD32057.1 - 0.18 11.7 7.3 2.1 8.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MSP7_C PF12948.7 PVD32057.1 - 0.32 11.7 7.6 0.061 14.0 3.8 1.8 2 0 0 2 2 1 0 MSP7-like protein C-terminal domain TPR_20 PF14561.6 PVD32057.1 - 0.42 11.0 4.2 13 6.2 0.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD32057.1 - 1.1 9.5 5.5 15 5.9 0.5 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RCC1 PF00415.18 PVD32058.1 - 2.1e-52 175.5 16.8 3e-12 46.9 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD32058.1 - 2.2e-22 78.3 32.4 5.1e-05 23.0 0.8 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PUA PF01472.20 PVD32058.1 - 0.036 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 PUA domain ChpA-C PF03777.13 PVD32058.1 - 0.51 10.3 4.9 0.23 11.4 1.5 2.2 2 0 0 2 2 2 0 ChpA-C Syndecan PF01034.20 PVD32059.1 - 1.1e-29 102.1 0.0 1.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Thyroglobulin_1 PF00086.18 PVD32059.1 - 2.2e-24 84.9 7.7 3.2e-14 52.3 2.5 2.4 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Glycophorin_A PF01102.18 PVD32059.1 - 0.00074 19.7 1.1 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Glycophorin A MGC-24 PF05283.11 PVD32059.1 - 0.00092 19.7 4.1 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin stn_TNFRSF12A PF12191.8 PVD32059.1 - 0.013 15.7 0.3 0.51 10.6 0.2 2.5 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2207 PF09972.9 PVD32059.1 - 0.02 13.6 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.16 PVD32059.1 - 0.063 12.0 0.3 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 PVD32059.1 - 0.1 12.5 4.7 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 PVD32059.1 - 1.4 9.1 9.7 5.1 7.3 0.6 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pepdidase_M14_N PF18027.1 PVD32060.1 - 2.3e-09 37.6 0.3 6.7e-09 36.1 0.3 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain DUF4824 PF16106.5 PVD32061.1 - 0.02 14.1 5.1 0.026 13.8 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) DUF445 PF04286.12 PVD32061.1 - 0.026 14.4 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HTH_18 PF12833.7 PVD32061.1 - 0.1 12.9 1.3 0.17 12.2 1.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.32 PVD32063.1 - 7.9e-11 42.3 6.5 5.9e-05 23.8 2.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.6 PVD32063.1 - 5.2 7.1 9.7 0.56 10.2 0.3 2.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C2H2_2 PF12756.7 PVD32063.1 - 7 7.0 10.7 0.31 11.4 1.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Med30 PF11315.8 PVD32064.1 - 1.3e-26 93.5 10.5 2e-26 93.0 10.5 1.3 1 1 0 1 1 1 1 Mediator complex subunit 30 Sigma70_ner PF04546.13 PVD32064.1 - 0.0007 19.5 3.5 0.0019 18.2 3.5 1.6 1 1 0 1 1 1 1 Sigma-70, non-essential region HBM PF16591.5 PVD32064.1 - 0.044 13.2 0.3 0.044 13.2 0.3 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain Csm2_III-A PF03750.13 PVD32064.1 - 0.19 12.6 4.8 1.3 9.9 3.8 2.3 1 1 0 1 1 1 0 Csm2 Type III-A KELK PF15796.5 PVD32064.1 - 0.45 11.0 6.4 1.9 9.0 0.2 2.3 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MCPsignal PF00015.21 PVD32064.1 - 1.6 8.5 9.1 2.4 8.0 1.4 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GTP_EFTU PF00009.27 PVD32065.1 - 1.9e-31 109.2 0.4 3.5e-31 108.3 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PVD32065.1 - 1.7e-24 86.3 0.0 3.9e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PVD32065.1 - 1.1e-14 54.6 3.4 4.5e-14 52.6 1.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PVD32065.1 - 0.00046 20.3 0.2 0.014 15.5 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 PVD32065.1 - 0.0042 17.0 0.4 0.0042 17.0 0.4 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 AAA_29 PF13555.6 PVD32065.1 - 0.0045 16.7 0.3 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD32065.1 - 0.058 13.5 0.2 11 6.0 0.1 3.0 3 0 0 3 3 3 0 Dynamin family PDCD2_C PF04194.13 PVD32066.1 - 1.7e-33 116.1 0.3 1.7e-33 116.1 0.3 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain MFS_1 PF07690.16 PVD32067.1 - 1.4e-15 57.1 27.1 2e-09 36.9 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 PVD32067.1 - 0.017 13.5 15.2 0.0039 15.6 9.8 1.9 1 1 1 2 2 2 0 Transmembrane secretion effector Ank_4 PF13637.6 PVD32068.1 - 1.2e-16 60.8 4.8 0.06 14.0 0.0 8.3 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD32068.1 - 2.5e-14 53.6 5.5 0.0003 21.3 0.1 5.2 5 2 1 6 6 4 4 Ankyrin repeats (3 copies) TPR_1 PF00515.28 PVD32068.1 - 6.3e-10 38.5 7.5 0.005 16.6 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD32068.1 - 7.1e-09 35.8 2.0 0.028 14.7 0.1 6.0 4 1 0 4 4 4 2 Tetratricopeptide repeat Ank PF00023.30 PVD32068.1 - 1.5e-08 34.7 0.1 0.076 13.5 0.0 5.5 4 0 0 4 4 4 1 Ankyrin repeat TPR_2 PF07719.17 PVD32068.1 - 3.9e-07 29.7 14.9 0.18 12.0 0.1 8.1 8 1 1 9 9 7 2 Tetratricopeptide repeat UvrD-helicase PF00580.21 PVD32068.1 - 7.1e-07 29.0 0.6 7.1e-07 29.0 0.6 5.2 6 0 0 6 6 5 1 UvrD/REP helicase N-terminal domain TPR_8 PF13181.6 PVD32068.1 - 1.3e-06 28.1 7.6 4.8 7.6 0.1 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat UvrD_C PF13361.6 PVD32068.1 - 1.3e-05 24.8 0.0 0.002 17.5 0.0 4.1 4 1 0 5 5 5 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PVD32068.1 - 9e-05 22.8 0.0 0.055 13.8 0.1 2.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 PVD32068.1 - 0.0001 22.1 0.0 0.71 9.7 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank_5 PF13857.6 PVD32068.1 - 0.00029 21.1 0.1 9.7 6.6 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD32068.1 - 0.00039 20.6 2.5 14 6.7 0.1 6.3 6 1 0 6 6 5 0 Ankyrin repeat AAA_22 PF13401.6 PVD32068.1 - 0.00059 20.1 0.9 3 8.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain TPR_19 PF14559.6 PVD32068.1 - 0.0031 18.0 0.2 7.7 7.1 0.1 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat MukF_M PF17192.4 PVD32068.1 - 0.0062 16.3 4.0 3.1 7.5 0.9 4.2 3 0 0 3 3 3 1 MukF middle domain TPR_11 PF13414.6 PVD32068.1 - 0.033 13.9 0.7 0.17 11.6 0.3 2.6 2 0 0 2 2 2 0 TPR repeat DUF4766 PF15973.5 PVD32068.1 - 0.081 13.5 4.9 0.22 12.1 4.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) TPR_10 PF13374.6 PVD32068.1 - 0.12 12.2 0.3 77 3.4 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 PVD32068.1 - 1.3 8.9 17.2 0.27 11.1 0.3 5.0 5 0 0 5 5 5 0 Region in Clathrin and VPS Amino_oxidase PF01593.24 PVD32069.1 - 1.2e-67 229.2 0.0 7.2e-66 223.3 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD32069.1 - 5.2e-08 33.0 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PVD32069.1 - 1.6e-07 31.5 0.2 0.00023 21.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 PVD32069.1 - 2.1e-07 30.5 1.5 8e-05 22.0 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD32069.1 - 6.2e-06 26.0 0.8 2.7e-05 23.9 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD32069.1 - 0.00082 18.6 0.1 0.0026 16.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 PVD32069.1 - 0.001 18.4 0.2 0.0022 17.3 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PVD32069.1 - 0.0022 16.8 6.6 0.09 11.5 0.1 3.7 5 0 0 5 5 5 2 HI0933-like protein Thi4 PF01946.17 PVD32069.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 PVD32069.1 - 0.0067 15.5 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 PVD32069.1 - 0.011 14.8 0.1 0.025 13.7 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PVD32069.1 - 0.017 14.4 0.4 2.2 7.5 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD32069.1 - 0.031 14.8 0.3 0.36 11.4 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PVD32069.1 - 0.086 12.1 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain SWM_repeat PF13753.6 PVD32069.1 - 0.15 12.2 0.1 33 4.7 0.1 2.6 2 0 0 2 2 2 0 Putative flagellar system-associated repeat DUF3139 PF11337.8 PVD32069.1 - 1.8 9.3 4.0 0.78 10.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) FAM167 PF11652.8 PVD32070.1 - 8.4e-32 109.5 3.4 8.4e-32 109.5 3.4 2.0 2 0 0 2 2 2 1 FAM167 T6SS_VasJ PF16989.5 PVD32070.1 - 0.00039 20.0 1.1 0.00057 19.4 1.1 1.2 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ LURAP PF14854.6 PVD32070.1 - 0.0058 16.6 0.2 0.0058 16.6 0.2 2.0 2 0 0 2 2 2 1 Leucine rich adaptor protein DUF2388 PF09498.10 PVD32070.1 - 0.025 14.5 0.6 0.062 13.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF2968 PF11180.8 PVD32070.1 - 0.032 13.9 4.2 0.052 13.2 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4404 PF14357.6 PVD32070.1 - 0.058 14.0 4.6 0.14 12.8 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) EzrA PF06160.12 PVD32070.1 - 0.093 10.9 0.6 0.13 10.4 0.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 PVD32070.1 - 0.11 12.9 0.4 0.58 10.7 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ING PF12998.7 PVD32070.1 - 0.18 12.4 2.4 0.33 11.6 2.4 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_C2 PF00648.21 PVD32071.1 - 2.1e-57 194.4 0.0 2.8e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD32071.1 - 3.3e-13 50.1 0.0 6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III Ras PF00071.22 PVD32072.1 - 1.2e-69 233.0 0.1 7.7e-43 145.9 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PVD32072.1 - 2e-53 179.7 0.7 7.2e-35 119.8 0.1 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32072.1 - 4.3e-22 78.4 0.2 8.7e-15 54.6 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD32072.1 - 6e-08 32.3 0.0 5.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD32072.1 - 1.2e-06 28.5 0.0 9.6e-05 22.4 0.0 2.8 1 1 1 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD32072.1 - 1e-05 25.2 0.9 0.019 14.5 0.8 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 PVD32072.1 - 3.1e-05 24.1 0.2 0.00031 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 PVD32072.1 - 0.00049 20.0 0.0 0.015 15.1 0.0 2.5 1 1 2 3 3 3 1 Conserved hypothetical ATP binding protein Sep15_SelM PF08806.11 PVD32072.1 - 0.0029 17.7 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 Sep15/SelM redox domain DUF3873 PF12989.7 PVD32072.1 - 0.0083 16.5 1.0 2.4 8.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function, B. Theta Gene description (DUF3873) SRPRB PF09439.10 PVD32072.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PVD32072.1 - 0.036 14.0 0.1 6.5 6.6 0.0 3.1 3 1 1 4 4 4 0 RsgA GTPase PduV-EutP PF10662.9 PVD32072.1 - 0.038 13.7 0.2 0.95 9.2 0.2 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PVD32072.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD32072.1 - 0.04 14.3 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 PVD32072.1 - 0.045 12.8 0.0 0.72 8.9 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain NACHT PF05729.12 PVD32072.1 - 0.056 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 PVD32072.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 PVD32072.1 - 0.095 12.9 0.5 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AAA_24 PF13479.6 PVD32072.1 - 0.1 12.3 0.2 0.9 9.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PVD32072.1 - 0.13 12.3 0.0 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) XendoU PF09412.10 PVD32073.1 - 3.8e-49 167.3 3.8 1e-30 106.9 1.7 2.0 2 0 0 2 2 2 2 Endoribonuclease XendoU Somatomedin_B PF01033.17 PVD32073.1 - 1.8e-10 41.1 12.6 3.2e-10 40.2 12.6 1.5 1 0 0 1 1 1 1 Somatomedin B domain DUF1533 PF07550.11 PVD32073.1 - 0.024 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Ras PF00071.22 PVD32075.1 - 4.4e-22 78.4 0.0 4.7e-20 71.8 0.0 2.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD32075.1 - 7.8e-13 48.7 0.0 1.4e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Amastin PF07344.11 PVD32075.1 - 0.0002 21.2 2.9 0.0002 21.2 2.9 2.1 2 1 0 2 2 2 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 PVD32075.1 - 0.0014 18.5 6.6 0.0031 17.4 6.6 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32075.1 - 0.0015 18.3 8.5 0.0015 18.3 8.5 2.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Arf PF00025.21 PVD32075.1 - 0.0022 17.5 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 PVD32075.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 PVD32075.1 - 0.041 13.6 0.0 0.092 12.5 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 PVD32075.1 - 0.09 12.3 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD32075.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 PVD32075.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Claudin_3 PF06653.11 PVD32075.1 - 3.2 7.7 8.7 28 4.6 8.7 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 PVD32076.1 - 0.00013 21.9 15.7 0.00016 21.6 15.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 PVD32076.1 - 0.00016 21.5 10.6 0.00016 21.5 10.6 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD32076.1 - 0.0096 15.7 13.3 0.0096 15.7 13.3 2.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD32076.1 - 0.01 15.8 16.6 0.069 13.1 16.6 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Gram_pos_anchor PF00746.21 PVD32076.1 - 0.015 15.2 3.7 0.49 10.4 0.1 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Antimicrobial_3 PF08025.11 PVD32076.1 - 0.02 14.8 1.2 0.047 13.6 1.2 1.6 1 0 0 1 1 1 0 Spider antimicrobial peptide DUF4293 PF14126.6 PVD32076.1 - 0.027 14.7 4.9 0.041 14.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4190 PF13828.6 PVD32076.1 - 0.041 13.6 0.1 0.041 13.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) DUF4013 PF13197.6 PVD32076.1 - 2.1 8.1 18.5 0.036 13.9 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) DUF2207 PF09972.9 PVD32076.1 - 4.8 5.8 6.7 1.5 7.5 4.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM37 PF15108.6 PVD32076.1 - 7 6.5 15.1 1.3e+02 2.4 15.1 2.1 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF202 PF02656.15 PVD32076.1 - 8 7.0 16.0 12 6.4 8.9 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF202) Amastin PF07344.11 PVD32077.1 - 3e-05 23.9 6.8 3e-05 23.9 6.8 1.8 1 1 1 2 2 2 1 Amastin surface glycoprotein Claudin_3 PF06653.11 PVD32077.1 - 0.00046 20.2 9.0 0.0014 18.6 9.0 1.7 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF3413 PF11893.8 PVD32077.1 - 0.019 14.2 0.6 0.019 14.2 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Peptidase_C33 PF05412.12 PVD32077.1 - 0.029 14.4 0.4 0.05 13.6 0.4 1.3 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase DUF2207 PF09972.9 PVD32077.1 - 0.83 8.3 4.5 0.99 8.1 4.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 PVD32077.1 - 2 8.1 19.3 0.16 11.7 12.1 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD32078.1 - 0.00068 19.6 8.6 0.00096 19.1 8.6 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 PVD32078.1 - 0.00099 19.0 8.6 0.00099 19.0 8.6 1.6 1 1 1 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD32078.1 - 0.054 13.2 16.7 0.78 9.5 13.0 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3413 PF11893.8 PVD32078.1 - 0.85 8.7 4.0 0.15 11.2 0.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Gram_pos_anchor PF00746.21 PVD32078.1 - 5.2 7.1 7.5 3.5 7.6 1.3 3.1 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Amastin PF07344.11 PVD32079.1 - 4.3e-06 26.7 3.6 4.3e-06 26.7 3.6 2.1 2 1 0 2 2 2 1 Amastin surface glycoprotein Claudin_3 PF06653.11 PVD32079.1 - 5.4e-06 26.4 2.9 9.8e-06 25.6 2.9 1.4 1 0 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 PVD32079.1 - 1.8e-05 24.6 3.6 2.7e-05 24.1 3.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3413 PF11893.8 PVD32079.1 - 0.00072 18.8 0.9 0.00093 18.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3413) Claudin_2 PF13903.6 PVD32079.1 - 0.28 10.9 13.3 0.057 13.2 7.8 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD32080.1 - 3.2e-09 36.9 34.3 7.8e-07 29.1 5.8 3.7 3 1 0 3 3 3 2 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 PVD32080.1 - 9.8e-09 35.2 33.0 9.3e-08 32.1 6.4 3.2 2 2 1 3 3 3 2 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD32080.1 - 0.00042 20.1 7.3 0.00042 20.1 7.3 4.5 3 2 2 5 5 5 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD32080.1 - 0.00071 19.5 6.3 0.00071 19.5 6.3 3.6 3 2 0 3 3 3 1 Tight junction protein, Claudin-like Chordopox_A33R PF05966.12 PVD32080.1 - 6.1 6.1 6.1 19 4.4 0.2 3.0 3 0 0 3 3 3 0 Chordopoxvirus A33R protein Claudin_2 PF13903.6 PVD32081.1 - 0.00014 21.7 11.3 0.00034 20.4 11.3 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 PVD32081.1 - 0.0003 20.7 4.2 0.00043 20.2 4.2 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 PVD32081.1 - 0.0014 18.5 6.6 0.0021 17.9 6.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family YpmT PF17431.2 PVD32081.1 - 0.013 15.5 1.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized YmpT-like Claudin_3 PF06653.11 PVD32081.1 - 0.17 11.8 5.5 0.23 11.4 5.5 1.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 PVD32082.1 - 1.1e-08 35.2 13.4 1.6e-08 34.6 13.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32082.1 - 0.00083 19.2 19.1 0.033 13.9 14.2 2.4 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD32082.1 - 0.024 14.6 16.1 0.12 12.3 16.1 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DNA_pack_C PF02499.15 PVD32082.1 - 0.045 12.7 0.4 0.077 11.9 0.4 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus Amastin PF07344.11 PVD32082.1 - 0.084 12.7 20.9 0.042 13.7 16.1 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.20 PVD32083.1 - 1.1e-08 35.2 12.2 1.4e-08 34.7 12.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32083.1 - 6.4e-06 26.1 19.3 0.013 15.2 14.4 2.5 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 PVD32083.1 - 0.0022 17.9 14.3 0.0022 17.9 14.3 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein DNA_pack_C PF02499.15 PVD32083.1 - 0.008 15.2 0.4 0.012 14.6 0.4 1.3 1 0 0 1 1 1 1 Probable DNA packing protein, C-terminus Claudin_3 PF06653.11 PVD32083.1 - 0.0083 16.1 15.5 0.031 14.2 15.5 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like MARVEL PF01284.23 PVD32083.1 - 3.9 7.5 14.9 3.2 7.8 4.5 2.3 1 1 1 2 2 2 0 Membrane-associating domain Claudin_2 PF13903.6 PVD32084.1 - 1.5e-06 28.1 12.8 0.00012 21.9 8.7 2.1 1 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD32084.1 - 1.1e-05 25.3 9.0 1.4e-05 25.0 9.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DuoxA PF10204.9 PVD32084.1 - 0.0059 15.6 3.9 0.0059 15.6 3.9 1.4 2 0 0 2 2 2 1 Dual oxidase maturation factor Claudin_3 PF06653.11 PVD32084.1 - 0.014 15.4 12.1 0.12 12.3 12.1 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Amastin PF07344.11 PVD32084.1 - 0.036 13.9 12.6 0.2 11.5 12.6 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Clc-like PF07062.12 PVD32084.1 - 3.8 6.9 9.1 30 4.0 0.0 2.3 1 1 1 2 2 2 0 Clc-like Claudin_2 PF13903.6 PVD32085.1 - 1.5e-08 34.6 9.9 3.8e-08 33.3 4.1 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD32085.1 - 8e-06 25.8 7.2 1e-05 25.5 7.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD32085.1 - 7.9e-05 22.7 5.3 0.00014 21.9 5.3 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 PVD32085.1 - 0.00031 20.6 2.3 0.00031 20.6 2.3 1.9 1 1 0 2 2 2 1 Amastin surface glycoprotein Oxidored_q2 PF00420.24 PVD32085.1 - 2.7 7.7 7.2 21 4.8 0.1 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PsbX PF06596.11 PVD32085.1 - 8.6 6.5 8.9 1.7 8.7 0.7 2.9 2 1 1 3 3 3 0 Photosystem II reaction centre X protein (PsbX) PMP22_Claudin PF00822.20 PVD32086.1 - 1.6e-08 34.6 10.4 1.9e-08 34.3 10.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32086.1 - 2.8e-06 27.2 9.7 2.8e-06 27.2 9.7 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 PVD32086.1 - 0.0017 17.4 2.2 0.0024 16.9 2.2 1.2 1 0 0 1 1 1 1 Dual oxidase maturation factor Amastin PF07344.11 PVD32086.1 - 0.19 11.6 14.4 0.042 13.7 9.0 2.0 1 1 1 2 2 2 0 Amastin surface glycoprotein Claudin_3 PF06653.11 PVD32086.1 - 4.3 7.3 15.9 98 2.8 16.0 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.12 PVD32086.1 - 4.5 6.7 11.8 11 5.5 0.4 2.1 1 1 1 2 2 2 0 Clc-like Amastin PF07344.11 PVD32087.1 - 4.5e-09 36.3 23.1 1.1e-05 25.3 4.0 2.6 2 1 0 2 2 2 2 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD32087.1 - 1.1e-06 28.5 28.4 3.4e-06 26.9 8.6 3.5 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD32087.1 - 0.00014 21.7 10.2 0.00014 21.7 10.2 2.4 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD32087.1 - 0.0004 20.4 21.7 0.0086 16.0 3.2 2.8 2 1 0 2 2 2 2 Tight junction protein, Claudin-like DUF4418 PF14387.6 PVD32087.1 - 0.9 9.8 15.3 0.39 10.9 2.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4418) TMEM210 PF15195.6 PVD32087.1 - 1.8 9.0 10.2 2.9 8.3 0.6 3.1 3 0 0 3 3 3 0 TMEM210 family Clc-like PF07062.12 PVD32087.1 - 9.1 5.7 22.2 3.2 7.2 3.2 3.1 2 2 1 3 3 3 0 Clc-like PMP22_Claudin PF00822.20 PVD32088.1 - 9.4e-08 32.1 7.9 1.2e-07 31.7 7.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32088.1 - 0.00017 21.4 13.3 0.0013 18.5 7.0 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 PVD32088.1 - 0.0006 19.7 6.9 0.0006 19.7 6.9 2.0 1 1 0 2 2 2 1 Amastin surface glycoprotein Claudin_3 PF06653.11 PVD32088.1 - 0.0072 16.3 10.1 0.031 14.2 10.1 1.9 1 1 0 1 1 1 1 Tight junction protein, Claudin-like SirB PF04247.12 PVD32088.1 - 0.15 12.2 2.6 0.61 10.2 0.3 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB SCAMP PF04144.13 PVD32088.1 - 0.28 11.5 4.4 0.13 12.6 1.9 1.6 1 1 0 2 2 2 0 SCAMP family DctQ PF04290.12 PVD32088.1 - 0.47 10.4 8.9 0.13 12.1 1.8 2.1 1 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_1 PF04531.13 PVD32088.1 - 1.6 9.4 4.6 1.2 9.7 0.1 2.5 2 1 1 3 3 3 0 Bacteriophage holin DUF4342 PF14242.6 PVD32088.1 - 4.1 7.5 6.3 13 5.9 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) DUF4231 PF14015.6 PVD32088.1 - 9.7 6.7 9.5 1.7 9.2 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Glyco_transf_11 PF01531.16 PVD32089.1 - 8.6e-59 199.2 2.9 8.9e-29 100.6 1.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 11 RVT_1 PF00078.27 PVD32089.1 - 1.3e-15 57.6 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) O-FucT PF10250.9 PVD32089.1 - 3e-12 46.9 3.8 9.8e-05 22.2 1.0 4.2 2 2 1 3 3 3 2 GDP-fucose protein O-fucosyltransferase PMP22_Claudin PF00822.20 PVD32089.1 - 2.1e-06 27.7 18.1 6.4e-06 26.1 4.0 2.9 4 0 0 4 4 4 2 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 PVD32089.1 - 7.5e-05 22.6 23.9 0.0013 18.6 7.7 3.3 2 2 0 2 2 2 2 Amastin surface glycoprotein Claudin_2 PF13903.6 PVD32089.1 - 8.7e-05 22.4 19.6 0.0097 15.7 5.6 3.6 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction Phage_holin_1 PF04531.13 PVD32089.1 - 0.0014 19.2 2.2 0.12 12.9 0.1 3.1 2 0 0 2 2 2 1 Bacteriophage holin Claudin_3 PF06653.11 PVD32089.1 - 0.0018 18.2 3.7 0.0018 18.2 3.7 2.9 2 0 0 2 2 2 1 Tight junction protein, Claudin-like ATS PF15445.6 PVD32089.1 - 0.0038 16.7 1.0 0.81 9.0 0.1 2.1 2 0 0 2 2 2 2 acidic terminal segments, variant surface antigen of PfEMP1 Glyco_transf_11 PF01531.16 PVD32090.1 - 1.7e-27 96.4 0.3 2.6e-27 95.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32090.1 - 3.4e-06 27.0 1.5 5e-05 23.1 0.8 2.4 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD32091.1 - 3.2e-38 131.6 0.4 4.2e-38 131.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32091.1 - 4.9e-06 26.5 2.8 0.00017 21.4 1.7 2.6 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase DENN PF02141.21 PVD32092.1 - 1.3e-36 126.3 4.2 1.3e-36 126.3 4.2 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 PVD32092.1 - 4.9e-07 30.4 0.1 1.6e-06 28.7 0.1 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 PVD32092.1 - 1e-05 25.4 1.0 1e-05 25.4 1.0 2.1 2 0 0 2 2 2 1 dDENN domain bPH_3 PF14470.6 PVD32092.1 - 0.0018 18.6 0.2 0.0069 16.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 PVD32092.1 - 0.023 14.9 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 ANAPC4_WD40 PF12894.7 PVD32092.1 - 0.054 13.8 0.1 7 7.0 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD32092.1 - 0.076 12.3 0.0 0.74 9.1 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain CBP_BcsR PF10945.8 PVD32092.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Reg_prop PF07494.11 PVD32092.1 - 0.55 10.6 3.5 42 4.9 0.1 4.3 4 0 0 4 4 4 0 Two component regulator propeller WD40 PF00400.32 PVD32092.1 - 2.9 8.9 13.9 5.3 8.1 0.0 5.6 6 0 0 6 6 6 0 WD domain, G-beta repeat PMP22_Claudin PF00822.20 PVD32094.1 - 6.2e-12 45.7 11.9 8.8e-12 45.2 11.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD32094.1 - 0.00053 20.0 15.8 0.0018 18.3 15.8 1.8 1 1 0 1 1 1 1 Tight junction protein, Claudin-like TauE PF01925.19 PVD32094.1 - 0.0023 17.6 8.7 0.0032 17.1 8.7 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Amastin PF07344.11 PVD32094.1 - 0.0046 16.8 16.5 0.012 15.5 16.1 1.9 1 1 0 1 1 1 1 Amastin surface glycoprotein MARVEL PF01284.23 PVD32094.1 - 0.0056 16.7 11.6 0.0056 16.7 11.6 2.1 1 1 1 2 2 2 1 Membrane-associating domain Claudin_2 PF13903.6 PVD32094.1 - 0.0076 16.0 15.4 0.0076 16.0 15.4 2.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 PVD32094.1 - 0.04 14.2 16.9 0.064 13.5 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Cytochrom_B_C PF00032.17 PVD32094.1 - 1.6 9.0 5.5 0.73 10.2 2.0 2.2 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Trp_oprn_chp PF09534.10 PVD32094.1 - 3.2 7.5 11.7 0.047 13.5 3.9 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2070 PF09843.9 PVD32094.1 - 6.5 4.9 10.5 7.5 4.7 10.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans_2 PF07885.16 PVD32095.1 - 1.7e-32 111.2 16.4 4.9e-17 61.7 6.2 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 PVD32095.1 - 3.8e-08 32.9 2.7 0.0032 16.7 0.0 2.2 1 1 1 2 2 2 2 Ion transport protein Phage_lysozyme PF00959.19 PVD32095.1 - 0.012 16.1 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 2 0 Phage lysozyme DUF2670 PF10875.8 PVD32095.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Ion_trans_2 PF07885.16 PVD32096.1 - 1.7e-32 111.2 19.7 1.2e-17 63.6 7.1 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 PVD32096.1 - 1.5e-06 27.7 4.9 0.021 14.1 2.8 2.2 1 1 0 2 2 2 2 Ion transport protein DUF2368 PF10166.9 PVD32096.1 - 0.0072 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) SLATT_1 PF18181.1 PVD32096.1 - 0.15 12.0 0.6 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Glyco_transf_7N PF13733.6 PVD32097.1 - 4.9e-45 152.5 0.0 7.1e-45 151.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD32097.1 - 1.3e-19 69.7 0.2 2.1e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_11 PF01531.16 PVD32098.1 - 4.4e-73 246.1 1.4 2e-36 125.7 0.3 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32098.1 - 1e-10 41.9 8.6 0.00015 21.6 1.6 3.4 2 2 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase CARD PF00619.21 PVD32098.1 - 0.0076 16.3 0.0 1.7 8.7 0.0 2.7 3 0 0 3 3 3 2 Caspase recruitment domain Glyco_transf_11 PF01531.16 PVD32099.1 - 1.7e-91 306.6 12.8 8.4e-35 120.4 0.2 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32099.1 - 3.3e-14 53.3 18.4 0.00013 21.8 1.6 3.9 2 2 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Fucokinase PF07959.12 PVD32099.1 - 2.4e-07 30.1 0.1 0.45 9.4 0.0 3.4 3 0 0 3 3 3 3 L-fucokinase PRKCSH-like PF12999.7 PVD32099.1 - 0.00032 20.5 0.0 3.1 7.6 0.0 3.2 3 0 0 3 3 3 2 Glucosidase II beta subunit-like Gtr1_RagA PF04670.12 PVD32099.1 - 0.001 18.5 0.2 11 5.3 0.0 3.2 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region DnaB_2 PF07261.11 PVD32099.1 - 0.012 15.3 0.0 9.8 6.0 0.0 2.9 3 0 0 3 3 3 0 Replication initiation and membrane attachment BAAT_C PF08840.11 PVD32099.1 - 0.014 15.3 0.1 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AF2331-like PF14556.6 PVD32099.1 - 0.027 15.0 3.6 36 5.0 0.1 3.8 4 0 0 4 4 4 0 AF2331-like NAGLU_C PF12972.7 PVD32099.1 - 0.073 12.6 1.9 22 4.5 0.1 3.1 3 0 0 3 3 3 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF4908 PF16252.5 PVD32099.1 - 0.18 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) Glyco_transf_11 PF01531.16 PVD32100.1 - 7.7e-19 68.0 0.0 8.1e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_11 PF01531.16 PVD32101.1 - 5.8e-32 111.1 0.3 6.9e-32 110.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32101.1 - 3.7e-06 26.9 1.1 4.4e-05 23.4 1.1 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD32102.1 - 4.9e-09 35.8 0.1 5.3e-09 35.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_11 PF01531.16 PVD32103.1 - 1e-06 28.2 0.1 1.6e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD32103.1 - 0.00017 21.4 0.1 0.00023 21.0 0.1 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase QVR PF17064.5 PVD32104.1 - 0.00046 20.4 7.7 0.00046 20.4 7.7 2.3 2 0 0 2 2 2 1 Sleepless protein DUF753 PF05444.12 PVD32104.1 - 0.016 15.2 9.9 0.022 14.8 4.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF753) Activin_recp PF01064.23 PVD32104.1 - 9.4 7.4 15.5 0.38 11.9 9.0 2.1 2 0 0 2 2 2 0 Activin types I and II receptor domain PHO4 PF01384.20 PVD32107.1 - 2.2e-130 434.6 12.1 2.2e-130 434.6 12.1 1.4 2 0 0 2 2 2 1 Phosphate transporter family Sm_multidrug_ex PF06695.11 PVD32107.1 - 0.038 14.6 9.2 0.21 12.2 4.6 3.7 3 1 0 3 3 3 0 Putative small multi-drug export protein COX4 PF02936.14 PVD32107.1 - 0.29 11.2 1.5 17 5.4 0.1 3.2 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV F420_oxidored PF03807.17 PVD32108.1 - 0.00011 22.7 0.1 0.00025 21.6 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 PVD32108.1 - 0.00034 20.3 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 PVD32108.1 - 0.00082 19.4 0.8 0.003 17.5 0.8 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 PVD32108.1 - 0.0048 16.5 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 PVD32108.1 - 0.019 15.8 0.0 0.036 14.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.17 PVD32108.1 - 0.15 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Frizzled PF01534.17 PVD32109.1 - 4.9e-54 183.6 21.0 2.6e-36 125.3 8.8 2.9 1 1 2 3 3 3 3 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 PVD32109.1 - 0.001 18.3 4.2 0.001 18.3 4.2 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Fz PF01392.22 PVD32109.1 - 0.021 15.4 2.8 0.046 14.3 2.8 1.7 1 0 0 1 1 1 0 Fz domain DUF4720 PF15846.5 PVD32109.1 - 0.085 12.7 0.3 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4720) DUF3377 PF11857.8 PVD32109.1 - 1.8 8.6 3.2 8.5 6.4 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3377) 7TM_GPCR_Srw PF10324.9 PVD32110.1 - 0.00056 19.3 0.6 0.00074 18.9 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD32111.1 - 0.00017 21.0 0.1 0.00019 20.8 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD32111.1 - 0.0072 15.7 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Btz PF09405.10 PVD32113.1 - 1.7e-06 28.4 12.3 1.7e-06 28.4 12.3 2.9 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Ank_2 PF12796.7 PVD32114.1 - 3.2e-15 56.5 0.1 1.9e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD32114.1 - 6.7e-15 55.3 0.4 1.7e-09 38.0 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD32114.1 - 7.4e-14 51.5 1.6 1.3e-05 25.4 0.6 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PVD32114.1 - 7.9e-13 47.4 1.1 0.00046 20.4 0.2 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 PVD32114.1 - 2.1e-05 24.7 0.0 0.00015 22.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Pox_D2 PF04701.13 PVD32114.1 - 0.072 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Pox virus D2 protein 7tm_1 PF00001.21 PVD32115.1 - 3.1e-23 82.4 0.0 3.4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD32115.1 - 0.0003 20.6 12.3 0.0013 18.6 12.3 1.8 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 PVD32117.1 - 1.5e-20 73.7 17.3 3.7e-20 72.3 17.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD32117.1 - 5e-05 23.2 6.5 0.00023 21.0 1.6 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 PVD32117.1 - 0.0025 17.2 6.2 0.0053 16.2 5.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Git3 PF11710.8 PVD32117.1 - 0.012 15.4 1.9 0.012 15.4 1.9 1.8 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF3267 PF11667.8 PVD32117.1 - 0.29 11.4 8.5 1.7 9.0 2.5 2.9 2 0 0 2 2 2 0 Putative zincin peptidase FtsX PF02687.21 PVD32117.1 - 2.9 8.4 12.4 0.25 11.9 1.2 3.2 3 0 0 3 3 3 0 FtsX-like permease family 7tm_1 PF00001.21 PVD32118.1 - 1.2e-17 64.1 12.6 1.2e-17 64.1 12.6 2.3 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 PVD32118.1 - 0.079 12.9 0.0 0.079 12.9 0.0 2.7 3 0 0 3 3 3 0 TMEM154 protein family DUF3671 PF12420.8 PVD32118.1 - 7.6 6.6 7.5 68 3.6 3.0 3.4 3 1 0 3 3 3 0 Protein of unknown function 7tm_1 PF00001.21 PVD32119.1 - 4.3e-16 59.0 4.9 7.8e-16 58.2 4.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1676 PF07898.13 PVD32119.1 - 0.077 13.0 1.7 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) FtsX PF02687.21 PVD32119.1 - 3.3 8.3 13.6 11 6.5 0.5 3.2 3 0 0 3 3 3 0 FtsX-like permease family Phage_holin_3_6 PF07332.11 PVD32119.1 - 7 6.7 9.4 24 5.0 0.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III 7tm_1 PF00001.21 PVD32120.1 - 2.3e-05 23.9 0.8 3.4e-05 23.3 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Yip1 PF04893.17 PVD32120.1 - 0.0056 16.4 2.0 0.0068 16.1 2.0 1.1 1 0 0 1 1 1 1 Yip1 domain Ac81 PF05820.11 PVD32120.1 - 0.19 11.2 0.5 0.26 10.8 0.5 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 7tm_1 PF00001.21 PVD32121.1 - 2.4e-11 43.5 2.1 3.1e-11 43.1 2.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 PVD32121.1 - 0.085 13.2 4.0 0.27 11.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) UPF0139 PF03669.13 PVD32121.1 - 0.52 10.2 3.9 0.26 11.2 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) 7tm_1 PF00001.21 PVD32122.1 - 2e-06 27.4 2.7 3.8e-06 26.4 2.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PUF PF00806.19 PVD32123.1 - 1.4e-69 226.1 7.1 8.7e-10 37.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat 7tm_1 PF00001.21 PVD32123.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BBP7 PF07585.11 PVD32123.1 - 0.078 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative beta barrel porin-7 (BBP7) DUF2709 PF10915.8 PVD32123.1 - 0.21 10.8 0.2 0.94 8.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2709) Clathrin_lg_ch PF01086.17 PVD32124.1 - 2.7e-51 174.9 31.6 3.2e-50 171.3 31.6 2.3 1 1 0 1 1 1 1 Clathrin light chain baeRF_family5 PF18846.1 PVD32124.1 - 0.8 9.9 10.4 1.3 9.2 10.4 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 DUF4407 PF14362.6 PVD32124.1 - 2.4 7.4 6.8 3.6 6.9 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_4 PF12799.7 PVD32125.1 - 1.8e-08 34.5 0.4 0.011 16.1 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD32125.1 - 9.5e-08 31.7 2.5 0.002 17.7 0.1 3.5 2 2 2 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 PVD32125.1 - 5.5e-05 22.9 0.3 0.0011 18.6 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat C12orf66_like PF09404.10 PVD32126.1 - 4e-136 454.4 6.1 6.1e-136 453.8 6.1 1.2 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like TPR_7 PF13176.6 PVD32126.1 - 0.029 14.4 0.7 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 PVD32128.1 - 9.6e-14 51.0 0.0 1.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD32128.1 - 0.00017 21.7 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif CAP_N PF01213.19 PVD32134.1 - 9.7e-112 373.5 1.8 4.5e-111 371.4 0.0 2.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 PVD32134.1 - 1.8e-64 216.1 6.7 2.7e-64 215.5 6.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 PVD32134.1 - 0.00063 19.5 6.0 0.0019 17.9 6.0 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C CD20 PF04103.15 PVD32135.1 - 0.028 14.5 9.3 0.062 13.4 8.2 2.0 1 1 1 2 2 2 0 CD20-like family DUF202 PF02656.15 PVD32135.1 - 0.68 10.4 8.8 13 6.3 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) VWD PF00094.25 PVD32136.1 - 1.1e-06 29.0 0.0 3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain Laminin_G_3 PF13385.6 PVD32136.1 - 6.4e-06 26.4 3.3 0.00035 20.8 0.6 3.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 PVD32136.1 - 0.0011 19.3 14.9 0.0011 19.3 14.9 6.2 6 0 0 6 6 6 3 EGF-like domain Laminin_G_3 PF13385.6 PVD32137.1 - 0.00088 19.4 0.1 0.012 15.7 0.0 2.6 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 PVD32137.1 - 0.0074 16.9 10.9 2.9 8.7 0.1 3.3 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 PVD32137.1 - 0.011 16.0 13.5 0.44 10.9 8.9 2.8 2 0 0 2 2 2 0 EGF-like domain DSL PF01414.19 PVD32137.1 - 0.016 15.5 13.5 0.044 14.0 13.5 1.8 1 0 0 1 1 1 0 Delta serrate ligand EGF_2 PF07974.13 PVD32137.1 - 0.019 15.3 28.5 0.098 13.0 14.8 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 PVD32137.1 - 1.5 9.0 24.7 6.2 7.0 12.4 2.5 1 1 1 2 2 2 0 Laminin EGF domain G8 PF10162.9 PVD32139.1 - 0.0058 16.7 0.5 0.29 11.2 0.0 3.6 3 0 0 3 3 3 1 G8 domain F5_F8_type_C PF00754.25 PVD32140.1 - 0.26 11.4 0.5 1 9.5 0.0 2.3 2 0 0 2 2 2 0 F5/8 type C domain Cmc1 PF08583.10 PVD32142.1 - 1.3e-14 54.0 8.0 2e-14 53.3 8.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tyrosinase PF00264.20 PVD32143.1 - 3.9e-34 118.9 3.1 8e-33 114.6 3.1 2.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Haemocyan_bet_s PF14830.6 PVD32143.1 - 1.3e-27 95.8 0.0 2.1e-18 66.2 0.0 2.8 2 0 0 2 2 2 2 Haemocyanin beta-sandwich DUF5053 PF16476.5 PVD32143.1 - 0.026 14.2 0.1 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Haemocyan_bet_s PF14830.6 PVD32144.1 - 1.8e-105 345.9 0.0 1.5e-34 118.0 0.0 4.4 4 0 0 4 4 4 4 Haemocyanin beta-sandwich Tyrosinase PF00264.20 PVD32144.1 - 1.3e-34 120.5 8.2 1.4e-16 61.5 0.1 3.5 3 0 0 3 3 3 3 Common central domain of tyrosinase Gly_transf_sug PF04488.15 PVD32145.1 - 1.5e-07 32.0 0.0 3.6e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD32145.1 - 0.0024 17.3 0.1 0.0038 16.6 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD32145.1 - 0.0095 15.3 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain SecA_DEAD PF07517.14 PVD32145.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain Gly_transf_sug PF04488.15 PVD32148.1 - 0.0015 19.1 0.1 0.0042 17.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Gly_transf_sug PF04488.15 PVD32149.1 - 0.014 16.0 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif EAR PF07897.11 PVD32149.1 - 0.043 13.4 0.5 0.08 12.6 0.5 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Gly_transf_sug PF04488.15 PVD32150.1 - 2.7e-07 31.1 0.0 6.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD32150.1 - 0.0077 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD32150.1 - 0.045 13.0 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain zf-C2H2 PF00096.26 PVD32151.1 - 1.4e-07 31.6 22.3 0.0016 18.7 2.7 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD32151.1 - 2.9e-05 24.3 1.9 2.9e-05 24.3 1.9 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD32151.1 - 0.00044 20.8 17.7 0.9 10.6 1.7 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD32151.1 - 0.0022 18.7 4.8 1.8 9.3 0.0 4.0 3 1 1 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-CHCC PF10276.9 PVD32151.1 - 0.15 12.2 5.3 5.2 7.2 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 PVD32151.1 - 0.92 9.9 11.9 4 7.8 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PVD32152.1 - 1.2e-14 53.8 66.1 0.00043 20.6 3.6 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD32152.1 - 3.7e-12 46.0 55.1 0.072 14.0 1.7 9.0 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD32152.1 - 3.9e-11 42.9 40.4 0.01 16.1 0.1 7.1 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD32152.1 - 1.4e-07 31.7 47.3 0.0094 16.3 0.4 7.7 7 1 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD32152.1 - 0.0045 17.0 2.0 0.0045 17.0 2.0 7.0 7 0 0 7 7 7 3 C2H2-type zinc finger AKAP95 PF04988.12 PVD32152.1 - 0.013 15.8 5.8 2.3 8.5 0.0 2.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_8 PF15909.5 PVD32152.1 - 0.14 12.5 24.7 0.13 12.5 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc ribbon PBP PF01161.20 PVD32154.1 - 5.7e-13 49.3 0.1 8.1e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 7tm_1 PF00001.21 PVD32155.1 - 1.3e-25 90.2 4.7 1.6e-25 89.9 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OppC_N PF12911.7 PVD32155.1 - 0.6 10.1 2.8 2 8.4 0.2 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF373 PF04123.13 PVD32155.1 - 8.6 5.7 10.7 0.48 9.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Ubiquitin_4 PF18036.1 PVD32156.1 - 9.7e-29 99.3 3.4 1.2e-28 99.0 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 PVD32156.1 - 4.1e-08 32.9 0.0 5.7e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 PVD32156.1 - 0.032 14.1 0.2 6.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Metallophos PF00149.28 PVD32157.1 - 2e-20 74.1 2.8 3.9e-20 73.2 1.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 PVD32157.1 - 0.00075 19.5 1.9 0.00075 19.5 1.9 2.1 2 0 0 2 2 2 1 Saposin-like type B, region 1 DUF1071 PF06378.11 PVD32158.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Haemocyan_bet_s PF14830.6 PVD32160.1 - 3.7e-29 100.7 0.0 6.8e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Haemocyanin beta-sandwich Tyrosinase PF00264.20 PVD32160.1 - 3.8e-15 56.8 1.0 6.5e-15 56.0 1.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 PVD32161.1 - 4.3e-209 691.0 63.3 1.3e-32 113.9 3.6 12.9 8 5 1 9 9 9 9 Common central domain of tyrosinase Haemocyan_bet_s PF14830.6 PVD32161.1 - 5.5e-187 607.7 0.1 6.5e-37 125.6 0.0 9.6 7 2 2 9 9 9 9 Haemocyanin beta-sandwich DUF5053 PF16476.5 PVD32161.1 - 0.00015 21.3 0.7 6.6 6.5 0.0 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF5053) DUF1018 PF06252.12 PVD32161.1 - 0.2 12.6 0.1 1.9e+02 3.0 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1018) Acetyltransf_1 PF00583.25 PVD32162.1 - 0.0004 20.6 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 PVD32162.1 - 0.052 13.7 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TIP120 PF08623.10 PVD32164.1 - 1.4e-65 220.1 0.9 1.4e-65 220.1 0.9 5.9 8 1 1 9 9 7 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 PVD32164.1 - 4.5e-26 91.1 4.5 0.00032 21.0 0.0 8.8 7 1 1 8 8 8 5 HEAT repeats HEAT PF02985.22 PVD32164.1 - 1.5e-20 71.5 20.3 0.14 12.5 0.0 13.8 15 0 0 15 15 11 5 HEAT repeat HEAT_EZ PF13513.6 PVD32164.1 - 2e-14 53.7 15.3 0.067 13.7 0.0 11.3 11 1 1 12 12 11 4 HEAT-like repeat Adaptin_N PF01602.20 PVD32164.1 - 7.9e-10 37.9 27.4 0.0044 15.6 1.3 7.5 3 3 2 7 7 7 3 Adaptin N terminal region Cnd1 PF12717.7 PVD32164.1 - 2.1e-09 37.7 23.9 0.00092 19.3 0.1 8.1 7 2 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 PVD32164.1 - 5e-07 29.5 7.2 0.0035 16.9 0.0 5.7 5 2 1 6 6 6 1 CLASP N terminal TAF6_C PF07571.13 PVD32164.1 - 2.4e-06 27.8 0.8 0.76 10.1 0.1 5.7 2 1 2 5 5 5 1 TAF6 C-terminal HEAT repeat domain UME PF08064.13 PVD32164.1 - 9.6e-06 25.5 14.8 0.22 11.4 0.0 8.9 8 2 1 10 10 10 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 PVD32164.1 - 4.7e-05 23.9 6.6 0.22 12.1 0.0 7.2 8 3 1 9 9 7 1 Vacuolar 14 Fab1-binding region Telomere_reg-2 PF10193.9 PVD32164.1 - 0.00011 22.6 6.5 1.1 9.7 0.1 5.6 5 0 0 5 5 4 1 Telomere length regulation protein Arm PF00514.23 PVD32164.1 - 0.00034 20.6 2.3 43 4.3 0.0 7.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 PVD32164.1 - 0.00054 19.9 14.0 0.0075 16.2 0.0 7.2 8 1 0 8 8 8 1 Domain of unknown function (DUF3385) VHS PF00790.19 PVD32164.1 - 0.0056 16.5 8.3 0.53 10.1 0.3 4.3 4 0 0 4 4 4 2 VHS domain V-ATPase_H_C PF11698.8 PVD32164.1 - 0.052 13.7 11.9 4.4 7.5 0.7 7.2 6 2 1 7 7 7 0 V-ATPase subunit H NUC173 PF08161.12 PVD32164.1 - 0.077 12.6 3.6 31 4.1 0.0 5.3 5 2 1 6 6 6 0 NUC173 domain DUF4042 PF13251.6 PVD32164.1 - 0.097 12.4 12.6 0.053 13.2 0.7 5.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4042) RasGEF_N_2 PF14663.6 PVD32164.1 - 0.22 11.9 0.8 15 6.0 0.1 4.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DNA_pol_phi PF04931.13 PVD32164.1 - 0.32 9.0 8.9 0.021 13.0 0.9 2.7 3 0 0 3 3 3 0 DNA polymerase phi Uso1_p115_head PF04869.14 PVD32164.1 - 0.72 8.9 4.6 1.2 8.1 0.0 3.6 5 0 0 5 5 5 0 Uso1 / p115 like vesicle tethering protein, head region V-ATPase_H_N PF03224.14 PVD32164.1 - 8.6 5.6 14.7 13 5.0 0.5 4.7 3 3 0 4 4 4 0 V-ATPase subunit H mTERF PF02536.14 PVD32165.1 - 3.2e-15 55.9 4.3 2.1e-10 40.1 0.0 3.1 2 1 1 3 3 3 3 mTERF Syntaphilin PF15290.6 PVD32166.1 - 2.9e-07 30.5 0.7 2.9e-07 30.5 0.7 2.8 2 1 1 3 3 3 1 Golgi-localised syntaxin-1-binding clamp Kinesin_assoc PF16183.5 PVD32166.1 - 0.045 13.9 6.9 0.15 12.2 6.9 1.8 1 0 0 1 1 1 0 Kinesin-associated AAA_13 PF13166.6 PVD32166.1 - 0.18 10.4 10.8 0.28 9.8 10.8 1.2 1 0 0 1 1 1 0 AAA domain DUF573 PF04504.14 PVD32166.1 - 0.47 11.1 4.8 0.39 11.4 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF1664 PF07889.12 PVD32166.1 - 0.48 10.5 9.7 1.1 9.3 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TetR_C_24 PF17932.1 PVD32166.1 - 0.56 10.5 6.0 0.18 12.1 1.4 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PIN_8 PF18476.1 PVD32166.1 - 1.4 8.7 9.8 3.1 7.6 9.8 1.5 1 0 0 1 1 1 0 PIN like domain DivIC PF04977.15 PVD32166.1 - 2.6 7.9 9.6 0.47 10.3 1.2 2.5 2 0 0 2 2 2 0 Septum formation initiator FAM76 PF16046.5 PVD32166.1 - 3 7.1 22.6 0.14 11.5 5.8 2.9 2 1 1 3 3 3 0 FAM76 protein 60KD_IMP PF02096.20 PVD32166.1 - 9.6 6.1 8.4 0.94 9.4 3.6 1.7 1 1 1 2 2 2 0 60Kd inner membrane protein GRIP PF01465.20 PVD32167.1 - 2.6e-05 24.1 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GRIP domain Methyltransf_11 PF08241.12 PVD32167.1 - 0.089 13.5 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain VWC PF00093.18 PVD32168.1 - 3.6e-05 24.0 38.9 7.1e-05 23.0 10.5 3.2 3 0 0 3 3 3 2 von Willebrand factor type C domain MIP PF00230.20 PVD32169.1 - 1.6e-24 86.9 0.1 2e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 PVD32170.1 - 5.9e-28 98.1 8.2 6.7e-28 97.9 8.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt PF01943.17 PVD32170.1 - 0.025 14.0 1.9 0.029 13.8 1.9 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ubiquitin PF00240.23 PVD32171.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 PVD32171.1 - 0.19 12.4 0.1 0.43 11.3 0.1 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD 14-3-3 PF00244.20 PVD32172.1 - 5.8e-97 323.5 4.7 6.7e-97 323.3 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaC_arch PF05377.11 PVD32172.1 - 0.00089 19.6 1.7 0.0019 18.6 1.7 1.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) CAP18_C PF12153.8 PVD32172.1 - 0.013 15.4 0.7 0.022 14.6 0.7 1.3 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) YebG PF07130.12 PVD32172.1 - 0.021 14.7 1.3 0.063 13.1 0.1 2.4 2 0 0 2 2 2 0 YebG protein PPE PF00823.19 PVD32172.1 - 0.09 12.9 0.5 0.17 11.9 0.3 1.6 1 1 0 1 1 1 0 PPE family RL10P_insert PF17777.1 PVD32173.1 - 2.8e-21 75.3 0.0 5.3e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Med2 PF11214.8 PVD32173.1 - 0.0029 17.7 0.1 0.0058 16.8 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 Ribosomal_L10 PF00466.20 PVD32173.1 - 0.0056 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 zf-C2H2 PF00096.26 PVD32174.1 - 4.1e-05 23.8 8.5 0.0037 17.6 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD32174.1 - 0.00044 20.6 7.6 0.027 14.9 0.3 2.7 2 1 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD32174.1 - 0.00083 20.0 7.8 0.48 11.4 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger C1_2 PF03107.16 PVD32174.1 - 0.011 16.0 1.9 2.9 8.3 0.3 2.4 2 0 0 2 2 2 0 C1 domain DUF3734 PF12536.8 PVD32174.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Patatin phospholipase CDC24_OB3 PF17244.2 PVD32174.1 - 2.8 7.6 5.5 8.5 6.0 5.5 1.8 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-H2C2_5 PF13909.6 PVD32175.1 - 1e-18 66.7 49.6 3.3e-07 29.9 2.7 6.4 6 0 0 6 6 6 6 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD32175.1 - 3.1e-10 39.9 57.9 0.00068 20.0 4.4 7.1 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD32175.1 - 3.5e-09 36.7 49.4 0.00018 21.8 5.3 7.7 8 0 0 8 8 8 4 Zinc-finger double domain OrsD PF12013.8 PVD32175.1 - 0.00041 20.8 25.6 0.02 15.3 0.8 5.7 4 2 1 5 5 5 3 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 PVD32175.1 - 0.0018 19.0 51.0 0.082 13.8 1.6 6.8 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD32175.1 - 1.5 9.2 0.0 1.5 9.2 0.0 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CUB PF00431.20 PVD32178.1 - 6.7e-07 29.6 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 CUB domain Ig_3 PF13927.6 PVD32179.1 - 1.1e-34 118.9 2.6 6.9e-11 42.6 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD32179.1 - 1.1e-29 102.3 0.0 1.3e-08 34.7 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32179.1 - 1.9e-22 79.4 2.2 7.3e-08 32.6 0.0 5.1 4 1 1 5 5 5 3 Immunoglobulin domain ig PF00047.25 PVD32179.1 - 1.1e-13 51.1 0.1 0.0012 19.0 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain Bravo_FIGEY PF13882.6 PVD32179.1 - 5.1e-12 47.0 2.9 1.1e-11 45.9 2.9 1.5 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 PVD32179.1 - 9.1e-10 38.7 4.6 0.052 13.7 0.0 7.2 5 3 1 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD32179.1 - 0.0013 18.7 0.1 0.4 10.8 0.0 3.0 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Syndecan PF01034.20 PVD32179.1 - 0.0098 15.8 0.2 0.025 14.5 0.2 1.6 1 0 0 1 1 1 1 Syndecan domain C1-set PF07654.15 PVD32179.1 - 0.012 16.0 0.3 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 PVD32179.1 - 0.08 13.0 0.1 26 4.9 0.0 3.4 3 0 0 3 3 3 0 C17orf99 Ig domain EphA2_TM PF14575.6 PVD32179.1 - 0.084 13.8 0.0 0.62 11.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD32179.1 - 0.37 10.7 0.1 0.37 10.7 0.1 1.6 2 0 0 2 2 1 0 TMEM154 protein family SKG6 PF08693.10 PVD32179.1 - 0.9 9.0 3.1 1.9 7.9 3.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ig_3 PF13927.6 PVD32180.1 - 3.5e-27 94.8 14.1 2.9e-11 43.8 0.2 5.8 4 1 2 6 6 6 4 Immunoglobulin domain I-set PF07679.16 PVD32180.1 - 1.7e-26 92.1 3.7 9.2e-12 44.9 0.1 4.5 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32180.1 - 2.2e-14 53.5 13.3 9.7e-06 25.8 0.1 5.0 4 2 1 5 5 5 3 Immunoglobulin domain ig PF00047.25 PVD32180.1 - 2.1e-12 47.0 10.8 0.00011 22.3 0.1 5.7 5 1 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 PVD32180.1 - 1.9e-09 37.6 13.4 5.5e-05 23.3 0.1 7.0 5 4 0 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD32180.1 - 1.8e-06 27.9 0.5 0.026 14.6 0.1 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 PVD32180.1 - 0.0011 19.1 0.9 0.62 10.4 0.1 3.2 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 PVD32180.1 - 0.0043 16.8 10.2 0.0054 16.5 0.8 4.2 4 1 0 4 4 4 1 Adenovirus E3 region protein CR1 GMC_oxred_C PF05199.13 PVD32180.1 - 0.095 13.2 0.0 19 5.8 0.0 2.5 2 0 0 2 2 2 0 GMC oxidoreductase Ig_3 PF13927.6 PVD32181.1 - 4.9e-42 142.4 24.2 2.4e-12 47.3 1.1 8.5 8 0 0 8 8 8 6 Immunoglobulin domain I-set PF07679.16 PVD32181.1 - 2.9e-36 123.4 11.9 1.4e-10 41.1 0.0 7.2 6 1 1 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32181.1 - 3.1e-21 75.5 18.7 8.9e-07 29.2 0.1 6.0 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 PVD32181.1 - 2.3e-19 69.4 16.5 9.4e-06 25.7 0.1 7.2 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 PVD32181.1 - 1e-09 38.6 19.7 0.063 13.5 0.0 9.5 8 5 2 10 10 10 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD32181.1 - 1.2e-05 25.3 3.8 0.2 11.7 0.2 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD32181.1 - 0.00031 20.5 13.5 0.018 14.8 0.4 4.5 4 1 0 4 4 4 2 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 PVD32181.1 - 0.007 16.5 0.6 1.8 8.8 0.1 3.8 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Methyltransf_FA PF12248.8 PVD32181.1 - 0.016 15.5 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase DUF1425 PF07233.12 PVD32181.1 - 0.02 14.8 0.0 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1425) Ig_4 PF16680.5 PVD32181.1 - 0.048 13.9 3.4 12 6.3 0.0 4.4 5 0 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain Nrf1_activ_bdg PF10492.9 PVD32181.1 - 0.93 10.2 3.5 4.8 7.9 0.2 3.0 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain Ig_3 PF13927.6 PVD32182.1 - 3.7e-33 114.0 11.7 5.4e-13 49.3 0.2 5.5 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD32182.1 - 5.8e-30 103.2 3.6 3.9e-12 46.1 0.1 4.4 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32182.1 - 5.7e-18 65.0 8.0 9.7e-07 29.0 0.1 4.6 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 PVD32182.1 - 6.3e-16 58.3 9.9 1.1e-06 28.8 0.1 5.1 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 PVD32182.1 - 6.1e-08 32.8 11.7 0.0052 16.9 0.2 7.0 5 4 1 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD32182.1 - 0.00023 21.2 0.9 0.31 11.1 0.0 3.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 PVD32182.1 - 0.001 19.1 0.6 16 5.6 0.0 4.9 5 0 0 5 5 5 1 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 PVD32182.1 - 0.0058 16.4 3.6 0.046 13.5 0.2 3.4 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_4 PF16680.5 PVD32182.1 - 0.032 14.5 0.3 4.6 7.6 0.0 3.1 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain DUF5640 PF18692.1 PVD32182.1 - 0.034 14.2 3.0 1.2 9.3 0.5 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5640) Izumo-Ig PF16706.5 PVD32182.1 - 0.12 12.5 0.0 15 5.7 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Gly_transf_sug PF04488.15 PVD32183.1 - 2.5e-07 31.2 0.0 7e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD32183.1 - 0.0032 16.9 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD32183.1 - 0.096 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain EAR PF07897.11 PVD32183.1 - 0.26 10.9 0.7 0.49 10.1 0.7 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Ig_3 PF13927.6 PVD32184.1 - 5.1e-32 110.3 8.8 3.1e-10 40.5 0.1 5.4 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 PVD32184.1 - 1.7e-29 101.7 1.7 3.5e-11 43.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32184.1 - 1.8e-16 60.2 8.0 6.2e-06 26.5 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD32184.1 - 1.3e-14 54.1 4.2 4.9e-07 29.8 0.0 3.9 4 1 0 4 4 3 2 Immunoglobulin domain Bravo_FIGEY PF13882.6 PVD32184.1 - 7.3e-14 52.9 1.5 1.9e-13 51.6 1.5 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 PVD32184.1 - 4e-10 39.8 5.7 0.0018 18.4 0.1 6.5 5 3 1 6 6 6 2 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD32184.1 - 0.00022 21.4 0.7 1.9 8.8 0.0 3.8 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD32184.1 - 0.00028 20.9 0.5 0.29 11.2 0.1 3.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Protocadherin PF08374.11 PVD32184.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.20 PVD32184.1 - 0.025 14.5 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Ig_C17orf99 PF17736.1 PVD32184.1 - 0.091 12.8 2.6 16 5.6 0.0 4.2 4 1 0 4 4 4 0 C17orf99 Ig domain EphA2_TM PF14575.6 PVD32184.1 - 0.14 13.1 0.0 0.34 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 PVD32184.1 - 0.16 12.1 0.1 14 5.8 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD32184.1 - 0.2 11.9 0.9 3.4 7.9 0.0 2.8 3 0 0 3 3 2 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 PVD32184.1 - 0.34 10.7 5.8 0.48 10.2 0.1 3.8 5 1 0 5 5 5 0 Adenovirus E3 region protein CR1 DUF4514 PF14986.6 PVD32184.1 - 0.62 10.1 2.2 1.3 9.1 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) DUF3827 PF12877.7 PVD32184.1 - 1.1 7.5 3.0 1.7 6.9 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ig_3 PF13927.6 PVD32185.1 - 1.4e-28 99.3 8.8 2.1e-10 41.1 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 PVD32185.1 - 3.2e-24 84.8 3.9 1.8e-09 37.6 0.0 4.3 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32185.1 - 6.1e-14 52.1 9.6 1.5e-06 28.5 0.0 4.3 3 2 2 5 5 5 2 Immunoglobulin domain ig PF00047.25 PVD32185.1 - 2.1e-11 43.8 5.7 7.9e-07 29.2 0.0 4.7 5 0 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 PVD32185.1 - 1.4e-09 38.1 4.2 0.00024 21.3 0.1 5.3 4 1 0 4 4 4 1 Immunoglobulin V-set domain Bravo_FIGEY PF13882.6 PVD32185.1 - 0.00039 21.7 0.8 0.0012 20.2 0.8 1.8 1 0 0 1 1 1 1 Bravo-like intracellular region Syndecan PF01034.20 PVD32185.1 - 0.0032 17.3 0.3 0.013 15.4 0.3 2.0 2 0 0 2 2 2 1 Syndecan domain RCR PF12273.8 PVD32185.1 - 0.017 15.8 0.2 0.17 12.6 0.0 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR1 PF02440.15 PVD32185.1 - 0.024 14.4 3.3 0.036 13.9 0.1 2.9 3 1 0 3 3 3 0 Adenovirus E3 region protein CR1 Protocadherin PF08374.11 PVD32185.1 - 0.029 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Protocadherin SCIMP PF15050.6 PVD32185.1 - 0.038 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 SCIMP protein DUF4514 PF14986.6 PVD32185.1 - 0.16 12.0 3.9 0.42 10.6 3.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Stevor PF17410.2 PVD32185.1 - 0.23 11.0 1.4 0.42 10.1 1.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3827 PF12877.7 PVD32185.1 - 0.44 8.9 5.2 0.71 8.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) I-set PF07679.16 PVD32186.1 - 8.8e-41 137.9 11.1 1.8e-09 37.5 0.0 7.1 7 0 0 7 7 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD32186.1 - 8.1e-37 125.7 19.3 7.8e-07 29.6 0.1 8.3 8 0 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 PVD32186.1 - 9.9e-26 89.8 10.7 1.1e-05 25.6 0.0 6.9 7 0 0 7 7 6 5 Immunoglobulin domain V-set PF07686.17 PVD32186.1 - 1.1e-19 70.6 17.5 9.9e-05 22.5 0.2 9.5 8 3 0 8 8 6 3 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD32186.1 - 6.9e-18 64.8 11.2 0.0027 18.0 0.0 6.4 6 0 0 6 6 6 4 Immunoglobulin domain SCIMP PF15050.6 PVD32186.1 - 6.3e-06 26.7 0.1 0.073 13.5 0.0 2.9 2 0 0 2 2 2 2 SCIMP protein Adeno_E3_CR2 PF02439.15 PVD32186.1 - 2.3e-05 24.1 15.6 0.017 14.8 7.3 2.5 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 Baculo_11_kDa PF06143.11 PVD32186.1 - 3.6e-05 23.2 1.2 0.24 11.0 0.2 2.8 2 0 0 2 2 2 2 Baculovirus 11 kDa family EphA2_TM PF14575.6 PVD32186.1 - 0.00012 22.9 0.1 0.38 11.6 0.0 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain C1-set PF07654.15 PVD32186.1 - 0.00053 20.3 9.4 0.16 12.4 0.1 4.4 5 0 0 5 5 2 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 PVD32186.1 - 0.0009 19.2 0.7 85 3.3 0.0 5.8 5 2 0 5 5 5 0 C17orf99 Ig domain Orthoreo_P10 PF07204.11 PVD32186.1 - 0.0018 18.2 0.6 0.73 9.8 0.1 2.7 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Cytomega_TRL10 PF06084.11 PVD32186.1 - 0.0019 18.2 0.2 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Cytomegalovirus TRL10 protein Orf78 PF06024.12 PVD32186.1 - 0.002 18.4 1.4 2.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Orf78 (ac78) Syndecan PF01034.20 PVD32186.1 - 0.0024 17.7 0.2 0.91 9.5 0.0 2.6 2 0 0 2 2 2 1 Syndecan domain TMEM154 PF15102.6 PVD32186.1 - 0.0039 17.1 2.1 1.8 8.5 0.4 2.6 2 0 0 2 2 2 2 TMEM154 protein family DuoxA PF10204.9 PVD32186.1 - 0.0043 16.1 1.2 2 7.4 0.2 2.2 2 0 0 2 2 2 2 Dual oxidase maturation factor AA_permease PF00324.21 PVD32186.1 - 0.0046 15.6 0.3 0.39 9.2 0.1 2.1 2 0 0 2 2 2 1 Amino acid permease DUF5080 PF16883.5 PVD32186.1 - 0.0046 17.1 3.3 0.25 11.4 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5080) L_HMGIC_fpl PF10242.9 PVD32186.1 - 0.0068 16.6 0.1 0.63 10.2 0.0 2.3 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Adeno_E3_CR1 PF02440.15 PVD32186.1 - 0.0069 16.1 4.5 2.2 8.1 0.4 3.7 3 1 0 3 3 2 2 Adenovirus E3 region protein CR1 DUF4232 PF14016.6 PVD32186.1 - 0.01 16.0 1.1 2.3 8.4 0.0 3.2 4 0 0 4 4 2 0 Protein of unknown function (DUF4232) MFS_Mycoplasma PF07672.13 PVD32186.1 - 0.012 14.9 0.3 2.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Mycoplasma MFS transporter Shisa PF13908.6 PVD32186.1 - 0.013 15.7 0.4 3.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RCR PF12273.8 PVD32186.1 - 0.017 15.8 4.8 1.2 9.8 0.1 3.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CrgA PF06781.12 PVD32186.1 - 0.017 15.1 0.9 3.1 7.9 0.2 2.6 2 0 0 2 2 2 0 Cell division protein CrgA MIG-14_Wnt-bd PF06664.12 PVD32186.1 - 0.021 14.1 0.3 0.97 8.6 0.0 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion ASFV_J13L PF05568.11 PVD32186.1 - 0.041 13.6 1.6 6.2 6.5 0.2 2.6 2 0 0 2 2 2 0 African swine fever virus J13L protein Protocadherin PF08374.11 PVD32186.1 - 0.049 13.6 0.5 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Protocadherin RGS12_usC PF16612.5 PVD32186.1 - 0.055 13.9 1.4 9.7 6.6 0.0 3.1 3 0 0 3 3 2 0 C-terminal unstructured region of RGS12 TMEM52 PF14979.6 PVD32186.1 - 0.093 12.6 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Transmembrane 52 Insulin_TMD PF17870.1 PVD32186.1 - 0.11 12.6 11.8 0.5 10.5 0.9 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment SIT PF15330.6 PVD32186.1 - 0.12 12.8 0.2 21 5.6 0.1 2.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Prominin PF05478.11 PVD32186.1 - 0.38 8.7 2.0 1.5 6.7 0.0 2.0 2 0 0 2 2 2 0 Prominin Collectrin PF16959.5 PVD32186.1 - 0.53 10.0 6.8 3.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Renal amino acid transporter CTV_P6 PF06706.11 PVD32186.1 - 0.53 10.0 6.5 4.2 7.2 1.1 2.7 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF3827 PF12877.7 PVD32186.1 - 0.59 8.4 4.0 2.7 6.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF2873 PF11395.8 PVD32186.1 - 0.93 9.4 15.0 0.37 10.7 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) DUF2769 PF10967.8 PVD32186.1 - 1.2 9.9 2.9 40 5.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) Asp5 PF17000.5 PVD32186.1 - 1.7 8.8 3.9 11 6.2 0.1 2.6 3 0 0 3 3 2 0 Accessory secretory protein Sec, Asp5 ODV-E18 PF10717.9 PVD32186.1 - 3.3 7.7 6.2 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SKG6 PF08693.10 PVD32186.1 - 4.1 6.9 14.4 2.2 7.8 4.9 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MTS PF05175.14 PVD32187.1 - 1.5e-11 44.1 0.0 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 PVD32187.1 - 4.7e-07 29.5 0.0 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PVD32187.1 - 8.8e-07 29.6 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD32187.1 - 5.7e-05 23.0 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD32187.1 - 9.7e-05 23.0 0.0 0.00023 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD32187.1 - 0.0024 18.5 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PVD32187.1 - 0.0096 16.9 0.0 0.019 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 PVD32187.1 - 0.042 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain adh_short PF00106.25 PVD32187.1 - 0.081 12.4 0.1 0.17 11.3 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Methyltransf_15 PF09445.10 PVD32187.1 - 0.18 11.4 0.5 0.64 9.6 0.2 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Ras PF00071.22 PVD32188.1 - 2.6e-32 111.6 0.0 3.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32188.1 - 8.9e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32188.1 - 3.3e-10 39.7 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD32188.1 - 0.00013 21.6 0.0 0.003 17.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD32188.1 - 0.0034 17.5 0.0 0.0079 16.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Tetraspanin PF00335.20 PVD32189.1 - 1e-26 94.1 6.4 1.2e-26 93.9 6.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1616 PF07760.11 PVD32189.1 - 0.24 10.7 2.9 0.39 10.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF3487 PF11990.8 PVD32189.1 - 1 9.3 7.6 0.2 11.6 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PI3_PI4_kinase PF00454.27 PVD32190.1 - 5.5e-36 124.6 0.7 2.6e-26 93.0 0.3 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Cupin_8 PF13621.6 PVD32191.1 - 8.2e-16 58.5 0.1 2.9e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 Cupin-like domain TEX33 PF15400.6 PVD32192.1 - 0.77 10.3 4.4 0.97 9.9 0.4 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family EIIBC-GUT_N PF03612.14 PVD32192.1 - 1 9.1 5.5 0.35 10.6 0.2 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus LMBR1 PF04791.16 PVD32192.1 - 5.3 5.8 4.9 6.7 5.5 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3040 PF11239.8 PVD32193.1 - 0.03 14.6 0.2 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) MFA1_2 PF17317.2 PVD32193.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 DDE_Tnp_IS66 PF03050.14 PVD32197.1 - 0.016 14.7 0.1 0.028 13.9 0.0 1.4 2 0 0 2 2 2 0 Transposase IS66 family Beta_helix PF13229.6 PVD32198.1 - 1.1e-57 194.3 67.7 1e-24 87.2 17.9 5.2 3 2 1 4 4 4 4 Right handed beta helix region NosD PF05048.13 PVD32198.1 - 8.6e-37 126.7 40.8 3.6e-16 59.2 6.1 5.4 3 2 1 5 5 5 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 PVD32198.1 - 1.3e-07 31.4 0.5 1.3e-07 31.4 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD32198.1 - 2.2e-07 30.6 0.7 7e-07 29.0 0.7 1.9 1 0 0 1 1 1 1 F-box domain HeLo PF14479.6 PVD32198.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation PDZ PF00595.24 PVD32199.1 - 1.1e-14 54.6 0.1 1.9e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD32199.1 - 1.9e-08 34.0 0.4 4e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD32199.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 PVD32199.1 - 0.0036 17.8 0.5 5.1 7.7 0.1 3.7 4 0 0 4 4 4 2 PH domain Tricorn_PDZ PF14685.6 PVD32199.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Sulfotransfer_1 PF00685.27 PVD32200.1 - 1.6e-14 54.1 0.0 5.9e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32200.1 - 9.8e-14 52.2 0.0 2.7e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family MRNIP PF15749.5 PVD32201.1 - 6.2e-09 36.6 2.2 6.2e-09 36.6 2.2 3.2 2 1 0 2 2 2 1 MRN-interacting protein Methyltransf_25 PF13649.6 PVD32201.1 - 6.9e-09 36.3 0.2 1.5e-07 32.0 0.1 2.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PVD32201.1 - 8e-08 32.0 0.3 1.8e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 PVD32201.1 - 4e-07 30.6 0.1 1.5e-06 28.8 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 PVD32201.1 - 1.1e-05 25.4 0.0 3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 PVD32201.1 - 3.1e-05 23.8 0.0 7.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PVD32201.1 - 0.00019 21.2 0.1 0.00048 19.8 0.1 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 PVD32201.1 - 0.0008 19.0 0.2 0.0017 17.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PVD32201.1 - 0.0027 17.6 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD32201.1 - 0.013 14.4 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 PVD32201.1 - 0.028 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase HECW_N PF16562.5 PVD32201.1 - 0.08 12.8 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 zf-C2H2 PF00096.26 PVD32202.1 - 1.6e-15 56.5 22.2 1.2e-05 25.5 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD32202.1 - 2.9e-14 52.8 16.9 2.8e-06 27.5 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD32202.1 - 4.2e-11 42.7 19.5 0.0021 18.8 0.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD32202.1 - 1.2e-07 31.5 21.8 3.1e-05 23.9 0.4 4.1 4 1 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD32202.1 - 0.00013 22.2 11.7 0.06 13.7 3.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 PVD32202.1 - 0.0024 18.1 5.9 0.34 11.2 0.0 2.9 3 0 0 3 3 2 2 TFIIH C1-like domain zf-C2HC_2 PF13913.6 PVD32202.1 - 0.013 15.4 11.7 0.63 10.0 0.3 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 PVD32202.1 - 0.016 15.3 6.3 0.1 12.7 2.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 PVD32202.1 - 0.02 15.0 14.6 0.48 10.6 3.2 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-met PF12874.7 PVD32202.1 - 0.059 13.8 11.1 1.4 9.4 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_2 PF03107.16 PVD32202.1 - 0.075 13.4 10.0 13 6.1 1.2 3.4 1 1 2 3 3 3 0 C1 domain CpXC PF14353.6 PVD32202.1 - 0.21 11.6 4.5 0.82 9.7 0.1 2.8 2 1 1 3 3 3 0 CpXC protein LIM PF00412.22 PVD32202.1 - 0.22 11.8 9.6 4.6 7.5 3.7 2.7 1 1 0 2 2 2 0 LIM domain zf-C2HE PF16278.5 PVD32202.1 - 0.45 11.0 11.2 1.5e+03 -0.3 11.1 3.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Yippee-Mis18 PF03226.14 PVD32202.1 - 0.51 10.6 3.3 2 8.7 3.0 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Di19 PF05605.12 PVD32202.1 - 1.6 9.1 12.5 1.4 9.2 5.0 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.18 PVD32202.1 - 1.8 8.7 9.8 16 5.6 0.5 3.6 4 0 0 4 4 3 0 XPA protein N-terminal FYVE PF01363.21 PVD32202.1 - 2.4 8.4 13.1 1.7e+02 2.4 13.0 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-CRD PF17979.1 PVD32202.1 - 2.5 8.2 10.6 2.9 8.0 3.9 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions PyrI_C PF02748.15 PVD32202.1 - 2.6 8.0 10.4 0.42 10.5 0.7 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Evr1_Alr PF04777.13 PVD32202.1 - 3.2 8.3 8.1 7.3 7.1 0.5 3.1 1 1 2 3 3 3 0 Erv1 / Alr family DUF2256 PF10013.9 PVD32202.1 - 5.9 7.1 10.1 18 5.6 0.7 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2180 PF09947.9 PVD32202.1 - 8.2 6.5 7.5 2.6 8.1 1.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-Nse PF11789.8 PVD32203.1 - 7e-19 67.4 0.2 1.1e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 PVD32203.1 - 0.00045 19.9 0.1 0.00087 19.0 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.15 PVD32203.1 - 0.0054 16.9 0.0 0.019 15.2 0.0 1.8 1 1 1 2 2 2 1 U-box domain Fib_alpha PF08702.10 PVD32203.1 - 0.42 10.8 5.4 0.17 12.1 1.7 2.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 PVD32204.1 - 2.7e-10 40.1 0.0 5.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD32204.1 - 2.5e-05 23.7 0.4 4.2e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PVD32204.1 - 7.7e-05 22.7 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PVD32204.1 - 0.0097 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 PVD32204.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.6 PVD32205.1 - 9.9e-13 47.9 18.5 6.8e-06 26.3 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD32205.1 - 3.9e-12 45.9 20.6 4.8e-05 23.6 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD32205.1 - 1.1e-08 35.1 19.7 0.0039 17.9 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD32205.1 - 2.6e-05 24.1 0.5 2.6e-05 24.1 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger C1_4 PF07975.12 PVD32205.1 - 0.001 19.3 8.8 0.052 13.8 0.3 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 PVD32205.1 - 0.0018 18.5 10.9 0.55 10.6 1.7 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 PVD32205.1 - 0.11 12.7 15.2 0.74 10.0 0.8 3.7 4 0 0 4 4 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 PVD32205.1 - 0.15 12.2 7.2 0.14 12.3 2.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 PVD32205.1 - 0.3 11.5 11.0 1.4 9.4 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XPA_N PF01286.18 PVD32205.1 - 0.43 10.7 7.3 8.7 6.5 0.3 3.4 3 0 0 3 3 3 0 XPA protein N-terminal LIM PF00412.22 PVD32205.1 - 1.1 9.6 10.0 9.2 6.6 0.3 2.9 2 1 0 2 2 2 0 LIM domain zf-CRD PF17979.1 PVD32205.1 - 1.1 9.3 8.2 1.7 8.7 2.1 2.4 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-C2H2_3rep PF18868.1 PVD32205.1 - 2 9.1 9.5 0.78 10.4 0.7 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2180 PF09947.9 PVD32205.1 - 3.5 7.7 5.2 1.2 9.2 0.7 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HE PF16278.5 PVD32205.1 - 4.8 7.7 11.2 2.5e+03 -1.0 11.2 3.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 PVD32205.1 - 9.9 6.4 12.9 1.1e+03 -0.1 12.9 2.6 1 1 0 1 1 1 0 FYVE zinc finger Lipocalin PF00061.23 PVD32206.1 - 3.5e-05 24.0 0.0 6.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 PVD32206.1 - 0.00023 21.1 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Amnionless PF14828.6 PVD32207.1 - 0.00033 19.6 0.1 0.00044 19.2 0.1 1.1 1 0 0 1 1 1 1 Amnionless Orf78 PF06024.12 PVD32207.1 - 0.0016 18.7 0.3 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 Orf78 (ac78) SID-1_RNA_chan PF13965.6 PVD32207.1 - 0.0018 16.8 0.4 0.0023 16.4 0.4 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 EphA2_TM PF14575.6 PVD32207.1 - 0.007 17.2 0.0 0.017 16.0 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD32207.1 - 0.0095 15.8 6.5 0.0095 15.8 6.5 2.0 1 1 0 1 1 1 1 TMEM154 protein family BatD PF13584.6 PVD32207.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance CcmD PF04995.14 PVD32207.1 - 0.046 13.8 0.3 0.077 13.1 0.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Stevor PF17410.2 PVD32207.1 - 0.079 12.5 0.2 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 PVD32207.1 - 0.08 13.0 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment GspL_C PF12693.7 PVD32207.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain TRP PF06011.12 PVD32207.1 - 0.085 11.6 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel MAP17 PF15807.5 PVD32207.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 stn_TNFRSF12A PF12191.8 PVD32207.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RIFIN PF02009.16 PVD32207.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 1 0 1 1 1 0 Rifin SpoIIIAH PF12685.7 PVD32207.1 - 0.79 9.5 0.0 0.79 9.5 0.0 2.3 2 1 0 2 2 2 0 SpoIIIAH-like protein EVI2A PF05399.11 PVD32207.1 - 1.1 8.8 8.1 0.14 11.7 3.1 1.9 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) PRIMA1 PF16101.5 PVD32207.1 - 1.7 8.7 19.7 7.7 6.6 5.5 3.2 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 SKG6 PF08693.10 PVD32207.1 - 1.8 8.0 9.0 5.9 6.4 9.0 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PVD32208.1 - 0.0035 18.2 0.0 0.013 16.3 0.0 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 PVD32208.1 - 0.032 14.1 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 PVD32208.1 - 0.07 13.4 0.0 0.28 11.5 0.0 2.1 1 1 0 1 1 1 0 Orf78 (ac78) DUF3377 PF11857.8 PVD32208.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM51 PF15345.6 PVD32208.1 - 0.13 12.1 1.0 0.26 11.1 0.2 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.6 PVD32208.1 - 1.3 8.9 9.3 0.27 11.2 3.4 2.3 1 1 1 2 2 2 0 TMEM154 protein family MCPsignal PF00015.21 PVD32209.1 - 1.2e-10 41.5 1.7 5.7e-05 23.0 0.2 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 PVD32209.1 - 1.1e-09 38.4 0.0 0.088 13.1 0.0 4.6 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 PVD32209.1 - 6.4e-08 32.8 9.4 0.0019 18.2 3.9 2.9 1 1 1 2 2 2 2 Serine rich protein interaction domain BLOC1_2 PF10046.9 PVD32209.1 - 3.7e-07 30.3 0.4 0.2 12.0 0.1 3.3 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Taeniidae_ag PF05596.11 PVD32209.1 - 1.9e-06 27.7 37.2 2.6 8.1 0.4 8.0 1 1 9 10 10 10 0 Taeniidae antigen CREPT PF16566.5 PVD32209.1 - 2e-06 28.0 9.8 0.0011 19.1 2.5 2.4 1 1 1 2 2 2 2 Cell-cycle alteration and expression-elevated protein in tumour APG17 PF04108.12 PVD32209.1 - 4.7e-06 26.0 8.2 0.0045 16.2 2.5 2.2 1 1 1 2 2 2 2 Autophagy protein Apg17 DUF1664 PF07889.12 PVD32209.1 - 1.3e-05 25.2 6.2 0.094 12.8 0.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 PVD32209.1 - 1.4e-05 25.4 3.6 1.7 9.1 3.6 4.8 1 1 0 1 1 1 1 Syntaxin-like protein CENP-H PF05837.12 PVD32209.1 - 1.5e-05 25.4 13.7 0.25 11.8 1.9 3.7 1 1 2 3 3 3 3 Centromere protein H (CENP-H) KxDL PF10241.9 PVD32209.1 - 3.6e-05 24.0 1.4 2 8.7 0.1 3.7 1 1 4 5 5 5 1 Uncharacterized conserved protein ApoLp-III PF07464.11 PVD32209.1 - 5.5e-05 23.3 0.1 0.018 15.2 0.1 2.6 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF4446 PF14584.6 PVD32209.1 - 6.3e-05 23.0 6.9 0.43 10.5 0.0 4.7 2 1 2 4 4 4 1 Protein of unknown function (DUF4446) Laminin_II PF06009.12 PVD32209.1 - 6.8e-05 22.9 0.0 0.96 9.5 0.0 3.1 1 1 1 2 2 2 2 Laminin Domain II AAA_13 PF13166.6 PVD32209.1 - 7e-05 21.7 0.1 0.00011 21.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain Vps5 PF09325.10 PVD32209.1 - 0.00024 20.7 1.8 0.0081 15.7 0.3 2.2 1 1 1 2 2 2 1 Vps5 C terminal like COG2 PF06148.11 PVD32209.1 - 0.00029 20.9 13.3 0.22 11.6 0.6 3.4 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 IFT57 PF10498.9 PVD32209.1 - 0.00033 19.7 2.8 0.01 14.8 0.8 2.4 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 PVD32209.1 - 0.00037 20.7 0.1 0.88 9.8 0.0 3.2 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain AIP3 PF03915.13 PVD32209.1 - 0.00039 19.6 0.2 0.0006 19.0 0.2 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lipoprotein_7 PF01540.16 PVD32209.1 - 0.00047 19.6 2.4 0.0041 16.5 1.2 2.5 1 1 1 2 2 2 2 Adhesin lipoprotein FliJ PF02050.16 PVD32209.1 - 0.00051 20.3 3.4 2 8.6 3.4 3.7 1 1 0 1 1 1 1 Flagellar FliJ protein DUF4200 PF13863.6 PVD32209.1 - 0.00091 19.6 5.9 0.13 12.6 0.7 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) EzrA PF06160.12 PVD32209.1 - 0.001 17.4 0.1 0.0023 16.2 0.0 1.6 2 0 0 2 2 1 1 Septation ring formation regulator, EzrA SKA1 PF07160.12 PVD32209.1 - 0.0011 18.9 19.8 0.21 11.4 0.7 3.8 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 PVD32209.1 - 0.0011 17.9 16.8 0.045 12.6 8.1 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein EspB PF05802.11 PVD32209.1 - 0.0012 18.8 0.2 6.4 6.7 0.0 3.7 1 1 2 3 3 3 0 Enterobacterial EspB protein Tropomyosin PF00261.20 PVD32209.1 - 0.0026 17.2 10.5 0.13 11.6 0.8 3.4 1 1 2 3 3 3 2 Tropomyosin Cnn_1N PF07989.11 PVD32209.1 - 0.0035 17.5 9.7 14 5.9 1.3 4.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 EphA2_TM PF14575.6 PVD32209.1 - 0.0039 18.0 0.3 0.024 15.5 0.0 2.5 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD32209.1 - 0.0049 16.9 1.3 0.016 15.2 0.1 2.1 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment FTCD_C PF04961.12 PVD32209.1 - 0.0055 16.5 17.5 1.1 9.0 3.8 3.6 2 1 0 3 3 3 1 Formiminotransferase-cyclodeaminase TPR_MLP1_2 PF07926.12 PVD32209.1 - 0.006 16.6 1.0 1 9.4 0.3 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein SH3BP5 PF05276.14 PVD32209.1 - 0.0073 16.1 13.3 0.028 14.2 3.0 2.7 2 1 1 3 3 2 2 SH3 domain-binding protein 5 (SH3BP5) CheZ PF04344.13 PVD32209.1 - 0.0083 16.1 0.4 0.047 13.6 0.3 2.1 1 1 1 2 2 2 1 Chemotaxis phosphatase, CheZ TMPIT PF07851.13 PVD32209.1 - 0.0096 15.2 25.7 4.7e+03 -3.5 25.7 2.9 1 1 0 1 1 0 0 TMPIT-like protein T3SSipB PF16535.5 PVD32209.1 - 0.016 15.7 5.1 2.9 8.4 0.4 3.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF745 PF05335.13 PVD32209.1 - 0.023 14.4 8.6 0.85 9.3 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ALIX_LYPXL_bnd PF13949.6 PVD32209.1 - 0.024 13.9 10.1 0.11 11.8 2.3 2.4 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Laminin_I PF06008.14 PVD32209.1 - 0.025 14.3 0.0 2.4 7.8 0.0 2.4 1 1 1 2 2 2 0 Laminin Domain I GAS PF13851.6 PVD32209.1 - 0.029 13.7 6.4 0.38 10.1 2.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AcylCoA_dehyd_C PF12186.8 PVD32209.1 - 0.032 14.4 12.4 39 4.4 0.2 4.7 1 1 2 3 3 3 0 Acyl-CoA dehydrogenase C terminal Filament PF00038.21 PVD32209.1 - 0.032 13.8 6.4 0.86 9.1 1.0 2.3 1 1 1 2 2 2 0 Intermediate filament protein Goodbye PF17109.5 PVD32209.1 - 0.033 14.7 1.3 2 8.9 1.1 3.1 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain FAM184 PF15665.5 PVD32209.1 - 0.048 13.4 5.1 0.077 12.8 5.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B WEMBL PF05701.11 PVD32209.1 - 0.053 12.2 2.3 1 8.0 0.1 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF3357 PF11837.8 PVD32209.1 - 0.06 13.8 0.2 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF5305 PF17231.2 PVD32209.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BatD PF13584.6 PVD32209.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4201 PF13870.6 PVD32209.1 - 0.085 12.6 8.3 1.3 8.7 1.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF1515 PF07439.11 PVD32209.1 - 0.086 12.9 0.4 12 6.0 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TarH PF02203.15 PVD32209.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue MAD PF05557.13 PVD32209.1 - 0.11 10.8 16.5 0.38 9.0 16.5 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein I_LWEQ PF01608.17 PVD32209.1 - 0.15 12.3 22.5 1.8e+04 -7.6 22.4 4.6 1 1 0 1 1 0 0 I/LWEQ domain DUF4834 PF16118.5 PVD32209.1 - 0.19 12.7 0.0 0.51 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Occludin_ELL PF07303.13 PVD32209.1 - 0.19 12.5 10.1 1.8e+03 -0.3 10.1 3.5 1 1 0 1 1 1 0 Occludin homology domain Mod_r PF07200.13 PVD32209.1 - 0.21 11.7 4.6 5.9 7.0 0.6 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ING PF12998.7 PVD32209.1 - 0.25 11.9 11.9 3.2e+02 2.0 0.2 3.7 2 1 1 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding HAUS6_N PF14661.6 PVD32209.1 - 0.25 10.9 11.5 0.76 9.3 0.4 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4533 PF15047.6 PVD32209.1 - 0.28 10.7 20.5 0.78 9.3 4.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4533) Orf78 PF06024.12 PVD32209.1 - 0.31 11.3 0.6 1.3 9.3 0.0 2.3 2 0 0 2 2 1 0 Orf78 (ac78) She9_MDM33 PF05546.11 PVD32209.1 - 0.32 10.8 2.6 25 4.6 0.2 3.2 2 1 1 3 3 3 0 She9 / Mdm33 family IKBKB_SDD PF18397.1 PVD32209.1 - 0.32 10.2 35.4 2 7.7 14.5 2.7 1 1 1 2 2 2 0 IQBAL scaffold dimerization domain ATG16 PF08614.11 PVD32209.1 - 0.33 11.2 2.5 4.2 7.6 0.0 2.9 2 1 2 4 4 2 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 PVD32209.1 - 0.51 9.7 14.9 1.3 8.4 11.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 BORCS8 PF10167.9 PVD32209.1 - 0.58 10.1 28.7 2.1e+02 1.9 10.2 4.9 1 1 1 2 2 1 0 BLOC-1-related complex sub-unit 8 DUF4298 PF14131.6 PVD32209.1 - 0.59 10.1 7.9 73 3.4 1.1 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4298) KELK PF15796.5 PVD32209.1 - 0.71 10.4 10.9 0.82 10.2 0.6 3.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FH2 PF02181.23 PVD32209.1 - 0.94 8.5 18.4 5.3 6.1 6.5 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain TMEM154 PF15102.6 PVD32209.1 - 1 9.3 4.3 2 8.3 3.3 2.0 1 1 0 1 1 1 0 TMEM154 protein family TMF_TATA_bd PF12325.8 PVD32209.1 - 1.3 9.2 7.0 16 5.8 1.0 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_GPO PF05929.11 PVD32209.1 - 1.4 8.4 7.5 58 3.2 4.3 3.3 2 1 0 2 2 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Myosin_tail_1 PF01576.19 PVD32209.1 - 1.5 6.5 7.3 2.2 6.0 7.3 1.1 1 0 0 1 1 1 0 Myosin tail Lebercilin PF15619.6 PVD32209.1 - 1.6 8.4 3.9 5.4 6.6 1.6 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Strumpellin PF10266.9 PVD32209.1 - 2.1 5.9 7.7 4.7 4.8 0.7 2.1 1 1 1 2 2 2 0 Hereditary spastic paraplegia protein strumpellin Jnk-SapK_ap_N PF09744.9 PVD32209.1 - 2.4 8.4 7.2 11 6.3 2.0 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 PVD32209.1 - 2.9 8.4 10.4 2.1e+03 -0.7 10.4 3.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 COG6 PF06419.11 PVD32209.1 - 5.7 5.0 26.2 2 6.6 6.6 3.3 1 1 1 2 2 1 0 Conserved oligomeric complex COG6 Tropomyosin_1 PF12718.7 PVD32209.1 - 5.8 7.1 9.5 5.8 7.1 0.4 3.4 2 1 2 4 4 3 0 Tropomyosin like GLE1 PF07817.13 PVD32209.1 - 5.8 6.0 11.4 9.2 5.4 2.8 2.7 1 1 1 2 2 2 0 GLE1-like protein UPF0449 PF15136.6 PVD32209.1 - 6 7.4 21.5 2.1e+02 2.5 5.3 5.2 2 2 1 3 3 2 0 Uncharacterised protein family UPF0449 Sigma70_ner PF04546.13 PVD32209.1 - 8.5 6.2 9.9 2.4 8.0 1.7 2.8 1 1 1 2 2 2 0 Sigma-70, non-essential region Sulfotransfer_2 PF03567.14 PVD32210.1 - 1.3e-12 48.2 2.2 5.3e-07 29.8 0.9 3.1 2 1 0 2 2 2 2 Sulfotransferase family PFK PF00365.20 PVD32211.1 - 2.4e-177 588.2 2.4 7.9e-110 366.7 0.8 3.1 2 1 1 3 3 3 3 Phosphofructokinase TetR_C_24 PF17932.1 PVD32211.1 - 0.11 12.8 0.1 16 5.8 0.0 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L19e PF01280.20 PVD32212.1 - 5.9e-65 217.7 12.5 5.9e-65 217.7 12.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e NMD3 PF04981.13 PVD32213.1 - 4.6e-56 190.0 10.0 3.6e-43 147.8 0.8 2.5 2 1 1 3 3 3 2 NMD3 family DUF1289 PF06945.13 PVD32213.1 - 0.34 10.7 3.2 8 6.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) zf-CCHC PF00098.23 PVD32214.1 - 0.00064 19.7 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD32214.1 - 0.0042 16.9 1.1 0.01 15.6 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PVD32214.1 - 0.083 12.6 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Exo_endo_phos PF03372.23 PVD32215.1 - 6.8e-09 35.6 0.0 9.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD32215.1 - 0.012 15.4 0.6 0.032 14.1 0.1 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase ETF PF01012.21 PVD32215.1 - 0.076 12.9 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain fn3 PF00041.21 PVD32216.1 - 9.4e-06 25.9 1.5 0.22 11.9 0.1 4.8 4 0 0 4 4 4 2 Fibronectin type III domain Ig_3 PF13927.6 PVD32216.1 - 0.00079 20.0 5.8 0.0083 16.7 0.1 4.3 5 0 0 5 5 5 1 Immunoglobulin domain ABC2_membrane_3 PF12698.7 PVD32216.1 - 0.0033 16.6 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ig PF00047.25 PVD32216.1 - 0.0058 16.8 0.1 0.035 14.3 0.1 2.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD32216.1 - 0.0076 16.6 2.1 0.015 15.7 0.1 2.6 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 PVD32216.1 - 0.16 12.1 0.7 0.76 9.9 0.1 2.6 3 0 0 3 3 3 0 Immunoglobulin I-set domain Piwi PF02171.17 PVD32217.1 - 2.3e-112 375.2 0.0 3.4e-112 374.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 PVD32217.1 - 7.3e-34 115.9 0.2 2.6e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 PVD32217.1 - 2.8e-25 88.7 0.5 5.3e-25 87.8 0.5 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PVD32217.1 - 2.3e-23 81.6 0.1 5.3e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PVD32217.1 - 8.3e-22 78.3 2.1 1.2e-19 71.3 0.1 3.0 2 1 1 3 3 3 2 N-terminal domain of argonaute ArgoL2 PF16488.5 PVD32217.1 - 2.9e-17 62.7 0.0 6.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain UNC45-central PF11701.8 PVD32218.1 - 8.8e-29 100.4 15.7 1.3e-28 99.9 0.4 4.8 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central Arm PF00514.23 PVD32218.1 - 1.1e-14 53.9 16.4 0.23 11.5 0.1 10.9 12 0 0 12 12 11 3 Armadillo/beta-catenin-like repeat TPR_1 PF00515.28 PVD32218.1 - 3.3e-14 52.0 7.2 1.2e-05 25.0 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD32218.1 - 2.5e-13 49.0 14.8 1.5e-05 24.7 0.1 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat HEAT_2 PF13646.6 PVD32218.1 - 6.3e-09 36.1 12.6 0.31 11.4 0.0 7.0 5 1 3 8 8 8 4 HEAT repeats TPR_16 PF13432.6 PVD32218.1 - 1.9e-07 31.6 3.9 0.044 14.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD32218.1 - 9.5e-06 25.3 2.4 0.0066 16.4 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD32218.1 - 1.1e-05 25.6 5.7 4.7e-05 23.6 0.3 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32218.1 - 2.1e-05 24.3 9.7 0.89 9.9 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD32218.1 - 0.0001 21.9 8.4 0.00022 20.8 0.2 3.8 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 PVD32218.1 - 0.00014 22.3 5.6 0.0085 16.6 0.4 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD32218.1 - 0.0015 18.7 4.1 0.017 15.3 0.4 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat PIG-L PF02585.17 PVD32218.1 - 0.011 16.4 0.3 15 6.2 0.0 4.2 3 1 1 4 4 4 0 GlcNAc-PI de-N-acetylase Fis1_TPR_C PF14853.6 PVD32218.1 - 0.03 14.4 1.3 40 4.4 0.1 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 PVD32218.1 - 0.052 14.4 11.2 4.5 8.3 0.0 5.8 6 1 1 7 7 5 0 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 PVD32218.1 - 0.14 12.3 5.5 0.57 10.3 0.1 4.4 4 1 1 5 5 5 0 V-ATPase subunit H HEAT PF02985.22 PVD32218.1 - 0.14 12.5 2.2 93 3.7 0.0 5.7 6 0 0 6 6 4 0 HEAT repeat SecA_PP_bind PF01043.20 PVD32218.1 - 0.25 12.0 3.7 0.45 11.2 0.0 3.2 3 3 0 3 3 3 0 SecA preprotein cross-linking domain BTAD PF03704.17 PVD32218.1 - 0.73 10.3 5.7 9.4 6.7 0.5 3.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain tRNA-synt_1d PF00750.19 PVD32218.1 - 1.2 8.0 6.6 2.9 6.7 0.1 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (R) ANAPC3 PF12895.7 PVD32218.1 - 6.8 7.0 7.5 3.5 7.9 1.4 3.5 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FMN_red PF03358.15 PVD32219.1 - 7.1e-27 94.0 0.0 9.6e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 PVD32219.1 - 0.0047 16.7 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 PVD32220.1 - 6.7e-29 100.6 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 PVD32220.1 - 5.8e-06 26.1 0.0 8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 PVD32220.1 - 0.056 13.7 0.0 3.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain TrkA_N PF02254.18 PVD32220.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 PVD32221.1 - 2.5e-55 187.7 0.0 3.3e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD32221.1 - 2.1e-21 76.4 0.0 4.2e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD32221.1 - 0.00031 20.7 0.0 0.00075 19.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PVD32221.1 - 0.0079 15.8 0.3 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 PVD32221.1 - 0.021 14.2 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PVD32221.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 PVD32221.1 - 0.085 12.4 0.9 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Cas9_Topo PF17894.1 PVD32221.1 - 0.089 12.9 0.0 4.1 7.5 0.0 2.8 2 1 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 SAE2 PF08573.10 PVD32223.1 - 1.7e-08 35.5 3.3 9.2e-05 23.5 0.2 4.1 2 2 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Exo_endo_phos PF03372.23 PVD32224.1 - 8e-07 28.8 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.6 PVD32224.1 - 0.0036 17.1 0.3 0.012 15.4 0.3 2.0 1 0 0 1 1 1 1 UBA-like domain Astacin PF01400.24 PVD32225.1 - 3.3e-38 131.2 0.0 6.5e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 PVD32225.1 - 0.00055 20.1 19.4 0.00055 20.1 19.4 3.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain Peptidase_M10 PF00413.24 PVD32225.1 - 0.46 10.3 1.9 0.9 9.4 0.4 2.0 2 1 0 2 2 2 0 Matrixin LLC1 PF14945.6 PVD32226.1 - 6.3e-08 33.2 1.5 8.6e-07 29.6 1.0 2.1 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein HMG_box PF00505.19 PVD32227.1 - 1.2e-29 102.5 34.6 5.9e-17 61.8 0.7 5.9 6 1 0 6 6 6 3 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD32227.1 - 4.4e-14 52.8 24.8 2.8e-09 37.4 0.2 4.2 5 0 0 5 5 5 3 HMG-box domain ZnuA PF01297.17 PVD32227.1 - 0.082 12.3 1.3 1.8 7.9 0.2 2.4 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic MHB PF16525.5 PVD32227.1 - 0.092 13.0 0.3 0.75 10.1 0.0 2.6 2 1 0 2 2 2 0 Haemophore, haem-binding DUF4872 PF16169.5 PVD32227.1 - 0.099 12.4 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) Myb_DNA-binding PF00249.31 PVD32227.1 - 0.12 12.6 1.8 0.25 11.6 0.8 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain ZYG-11_interact PF05884.12 PVD32227.1 - 0.23 10.9 1.6 4.5 6.6 0.6 2.2 2 0 0 2 2 2 0 Interactor of ZYG-11 Phe_tRNA-synt_N PF02912.18 PVD32227.1 - 1.5 8.8 6.5 0.54 10.2 1.4 2.8 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Salp15 PF12115.8 PVD32227.1 - 5.3 7.5 6.2 3.1 8.3 2.4 2.4 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation EF1_GNE PF00736.19 PVD32228.1 - 3.9e-34 116.7 4.1 3.9e-34 116.7 4.1 2.1 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 PVD32228.1 - 8.1e-07 29.4 5.0 8.1e-07 29.4 5.0 3.6 3 0 0 3 3 2 1 Eukaryotic elongation factor 1 beta central acidic region DASH_Spc19 PF08287.11 PVD32228.1 - 0.002 18.1 2.2 0.003 17.5 1.7 1.6 1 1 0 1 1 1 1 Spc19 CCDC106 PF15794.5 PVD32228.1 - 0.0095 15.7 1.3 0.019 14.6 1.3 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Fes1 PF08609.10 PVD32228.1 - 0.023 15.6 8.0 0.048 14.5 0.1 2.9 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 AATF-Che1 PF13339.6 PVD32228.1 - 0.025 15.2 1.9 0.027 15.2 0.6 1.7 2 0 0 2 2 1 0 Apoptosis antagonizing transcription factor MinC_N PF05209.13 PVD32228.1 - 0.026 14.5 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Senescence PF06911.12 PVD32228.1 - 0.057 13.7 0.3 0.083 13.2 0.3 1.3 1 0 0 1 1 1 0 Senescence-associated protein Cwf_Cwc_15 PF04889.12 PVD32228.1 - 0.18 11.5 12.7 0.31 10.7 12.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BST2 PF16716.5 PVD32228.1 - 0.25 11.9 4.7 1.6 9.4 0.2 3.2 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 PVD32228.1 - 0.36 11.4 6.2 0.32 11.6 0.7 3.1 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Striatin PF08232.12 PVD32228.1 - 1 10.0 8.1 0.16 12.6 2.5 2.0 1 1 1 2 2 2 0 Striatin family Pox_Ag35 PF03286.14 PVD32228.1 - 8.9 6.0 14.9 11 5.8 0.4 2.3 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Sulfotransfer_1 PF00685.27 PVD32231.1 - 5.8e-10 39.1 0.0 1.1e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32231.1 - 9e-10 39.3 0.4 1.7e-09 38.4 0.4 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32232.1 - 0.0073 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain IRS PF02174.17 PVD32233.1 - 5.9e-22 77.4 0.0 1.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 PVD32233.1 - 3.4e-07 30.7 0.6 2.8e-06 27.8 0.7 2.3 2 0 0 2 2 2 1 PH domain Astacin PF01400.24 PVD32233.1 - 0.017 14.7 1.3 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) PH_11 PF15413.6 PVD32233.1 - 0.078 13.4 0.2 0.26 11.7 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain CSD PF00313.22 PVD32235.1 - 0.016 15.0 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain MBOAT PF03062.19 PVD32236.1 - 9.7e-15 54.8 7.5 9.7e-15 54.8 7.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 PVD32236.1 - 0.053 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) DUF2244 PF10003.9 PVD32236.1 - 0.44 10.2 8.8 1.9 8.1 0.3 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) WD40 PF00400.32 PVD32237.1 - 1e-52 174.9 8.5 5.6e-07 30.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32237.1 - 2.4e-12 47.0 0.0 0.2 12.0 0.0 5.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD32237.1 - 1.4e-09 37.4 0.0 0.003 16.6 0.0 3.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD32237.1 - 1.6e-07 31.4 0.1 0.013 15.4 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD32237.1 - 0.0058 15.3 1.5 6.5 5.3 0.0 3.7 1 1 3 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 PVD32237.1 - 0.019 14.9 4.0 9.8 6.2 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 PVD32237.1 - 0.035 13.4 0.1 2.8 7.2 0.0 3.3 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 PVD32237.1 - 0.041 12.4 0.1 0.26 9.8 0.1 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain nos_propeller PF18764.1 PVD32237.1 - 0.087 12.7 0.0 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat WD40_like PF17005.5 PVD32237.1 - 0.15 11.4 0.0 11 5.3 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain tRNA_int_endo PF01974.17 PVD32238.1 - 2.2e-19 69.3 0.1 4.5e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MCM PF00493.23 PVD32239.1 - 1e-93 312.6 0.0 1.7e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PVD32239.1 - 9.1e-25 86.9 0.2 6.1e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 PVD32239.1 - 1.4e-21 76.7 0.8 3.6e-21 75.4 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PVD32239.1 - 2.2e-11 44.3 2.0 5.1e-11 43.1 0.2 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PVD32239.1 - 2.3e-07 30.4 0.0 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PVD32239.1 - 0.00098 19.0 0.1 0.041 13.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD32239.1 - 0.01 15.9 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PVD32239.1 - 0.011 15.9 0.3 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mis14 PF08641.12 PVD32239.1 - 0.014 15.8 0.3 0.059 13.7 0.3 2.1 1 0 0 1 1 1 0 Kinetochore protein Mis14 like CDT1_C PF16679.5 PVD32239.1 - 0.021 15.2 1.1 0.021 15.2 1.1 2.7 3 0 0 3 3 2 0 DNA replication factor Cdt1 C-terminal domain ABATE PF07336.11 PVD32239.1 - 0.04 14.6 0.1 0.096 13.3 0.1 1.6 1 0 0 1 1 1 0 Putative stress-induced transcription regulator Sigma54_activat PF00158.26 PVD32239.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Ada3 PF10198.9 PVD32239.1 - 8.4 6.5 8.0 5.7 7.1 0.4 2.7 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 Pkinase_Tyr PF07714.17 PVD32240.1 - 9.9e-53 179.1 0.1 2.1e-34 119.0 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD32240.1 - 8.6e-30 104.0 0.0 1.3e-22 80.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PVD32240.1 - 0.00012 21.5 0.0 0.00032 20.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD32240.1 - 0.00017 20.5 0.0 0.00033 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PVD32240.1 - 0.059 12.7 0.6 11 5.3 0.1 3.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family ZapB PF06005.12 PVD32241.1 - 0.021 15.3 1.9 0.021 15.3 1.9 2.1 3 0 0 3 3 3 0 Cell division protein ZapB ATG16 PF08614.11 PVD32241.1 - 0.082 13.1 6.7 0.15 12.3 6.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 PVD32241.1 - 0.4 10.8 1.8 0.79 9.9 1.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DEC-1_N PF04625.13 PVD32241.1 - 9.5 5.1 13.0 14 4.6 12.5 1.5 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region RICH PF05062.12 PVD32242.1 - 0.48 10.8 4.0 1.1 9.7 4.0 1.6 1 0 0 1 1 1 0 RICH domain RVT_1 PF00078.27 PVD32243.1 - 6.5e-33 114.1 0.0 1.4e-32 113.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 PVD32243.1 - 4.5e-15 56.1 0.0 7.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 PVD32243.1 - 0.00026 20.8 0.1 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Exo_endo_phos_2 PF14529.6 PVD32243.1 - 0.0012 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase H_lectin PF09458.10 PVD32244.1 - 0.00016 21.8 0.6 0.0079 16.4 0.1 2.5 2 0 0 2 2 2 1 H-type lectin domain DUF4618 PF15397.6 PVD32244.1 - 0.041 13.3 2.0 0.34 10.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 PVD32244.1 - 0.13 11.1 2.8 0.14 11.1 1.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 PVD32244.1 - 0.2 10.9 6.3 0.3 10.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LTXXQ PF07813.12 PVD32245.1 - 0.0051 17.5 1.3 0.93 10.2 0.1 2.4 2 0 0 2 2 2 2 LTXXQ motif family protein RICH PF05062.12 PVD32245.1 - 0.017 15.4 1.1 0.12 12.8 1.0 2.0 2 0 0 2 2 2 0 RICH domain WASH_WAHD PF11945.8 PVD32245.1 - 0.028 13.9 0.7 0.051 13.1 0.5 1.5 1 1 0 1 1 1 0 WAHD domain of WASH complex MnmE_helical PF12631.7 PVD32245.1 - 0.076 13.2 2.1 0.12 12.6 2.1 1.2 1 0 0 1 1 1 0 MnmE helical domain Baculo_PEP_C PF04513.12 PVD32245.1 - 0.091 12.8 10.2 0.63 10.1 3.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.12 PVD32245.1 - 1.8 9.0 11.4 1 9.9 2.9 2.3 1 1 1 2 2 2 0 FlgN protein H_lectin PF09458.10 PVD32246.1 - 0.016 15.4 3.8 0.11 12.7 0.2 2.4 2 0 0 2 2 2 0 H-type lectin domain Glyco_hydro_38C PF07748.13 PVD32246.1 - 1.2 9.2 11.5 7.6 6.5 0.5 3.3 1 1 2 3 3 3 0 Glycosyl hydrolases family 38 C-terminal domain Trp_ring PF18669.1 PVD32246.1 - 1.7 8.9 5.3 1.3 9.2 1.6 2.4 1 1 1 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain KRTAP PF11759.8 PVD32247.1 - 0.0012 19.3 8.9 0.0012 19.3 8.9 1.9 3 0 0 3 3 3 1 Keratin-associated matrix ATG16 PF08614.11 PVD32248.1 - 0.0053 17.0 2.8 0.0086 16.3 2.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 PVD32248.1 - 0.0057 16.5 8.3 0.011 15.5 8.2 1.5 1 1 0 1 1 1 1 Phage minor structural protein GP20 VIR_N PF15912.5 PVD32248.1 - 0.021 14.4 1.2 0.035 13.7 1.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Spc7 PF08317.11 PVD32248.1 - 0.022 13.7 3.2 0.03 13.2 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MAD PF05557.13 PVD32248.1 - 0.022 13.1 2.5 0.028 12.8 2.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Vps53_N PF04100.12 PVD32248.1 - 0.034 13.1 5.4 0.055 12.4 5.4 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal CENP-K PF11802.8 PVD32248.1 - 0.094 12.3 3.0 0.13 11.8 3.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Dynamitin PF04912.14 PVD32248.1 - 0.16 11.3 7.0 0.32 10.3 7.1 1.3 1 1 0 1 1 1 0 Dynamitin ptaRNA1_toxin PF12703.7 PVD32248.1 - 0.25 11.4 1.2 6.7 6.8 0.1 2.8 1 1 2 3 3 3 0 Toxin of toxin-antitoxin type 1 system Fib_alpha PF08702.10 PVD32248.1 - 1.2 9.3 3.3 1.4 9.1 2.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 PVD32248.1 - 2 8.9 6.4 0.46 10.9 2.4 1.9 1 1 1 2 2 2 0 Cell division protein ZapB LINES_C PF14695.6 PVD32249.1 - 0.038 13.4 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Lines C-terminus APG17 PF04108.12 PVD32249.1 - 0.05 12.7 10.4 0.059 12.5 6.2 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF4407 PF14362.6 PVD32249.1 - 0.18 11.1 12.5 0.26 10.6 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MafB PF06255.13 PVD32249.1 - 0.43 10.0 2.5 0.57 9.6 2.5 1.1 1 0 0 1 1 1 0 Neisseria toxin MafB DUF2913 PF11140.8 PVD32249.1 - 0.56 9.9 3.9 3.1 7.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2913) Allexi_40kDa PF05549.11 PVD32249.1 - 0.57 9.7 2.7 0.99 8.9 2.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein ApoLp-III PF07464.11 PVD32249.1 - 0.65 10.1 11.1 7 6.7 0.2 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2666 PF10869.8 PVD32249.1 - 2 8.6 6.6 10 6.3 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2666) PNPase PF03726.14 PVD32249.1 - 2.8 8.5 8.7 1.1 9.8 0.8 2.9 2 2 1 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF1640 PF07798.11 PVD32249.1 - 3.2 7.8 14.6 0.42 10.6 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.11 PVD32249.1 - 4.5 7.9 7.7 9.8 6.8 3.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 PVD32249.1 - 5.2 7.1 14.1 4.3 7.4 2.8 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 PVD32250.1 - 0.0072 16.5 7.5 0.008 16.4 5.2 2.1 2 0 0 2 2 2 1 Haemolysin XhlA Tropomyosin_1 PF12718.7 PVD32250.1 - 0.035 14.3 3.0 0.062 13.5 3.0 1.4 1 0 0 1 1 1 0 Tropomyosin like CENP-Q PF13094.6 PVD32250.1 - 0.052 13.7 2.5 0.7 10.1 1.4 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 PVD32250.1 - 0.14 12.7 1.2 0.36 11.4 1.2 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 PVD32250.1 - 0.23 11.5 4.9 0.59 10.2 4.9 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 PVD32250.1 - 0.25 11.6 2.3 0.9 9.8 2.3 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain Spc7 PF08317.11 PVD32250.1 - 0.58 9.0 5.0 0.8 8.5 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 PVD32250.1 - 0.87 9.7 6.9 0.1 12.7 2.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Stm1_N PF09598.10 PVD32250.1 - 1.9 9.4 0.0 1.9 9.4 0.0 2.4 2 0 0 2 2 2 0 Stm1 SlyX PF04102.12 PVD32250.1 - 4.8 7.9 8.2 4.2 8.1 2.0 3.2 1 1 2 3 3 3 0 SlyX XhlA PF10779.9 PVD32251.1 - 0.023 14.9 5.5 0.084 13.1 5.5 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Syntaxin-6_N PF09177.11 PVD32251.1 - 0.081 13.5 1.9 0.2 12.2 1.9 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Spc7 PF08317.11 PVD32251.1 - 0.18 10.7 6.3 0.25 10.2 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 PVD32251.1 - 0.23 11.9 1.2 0.67 10.4 1.2 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Vps53_N PF04100.12 PVD32251.1 - 0.46 9.4 6.5 0.9 8.4 6.5 1.4 1 1 0 1 1 1 0 Vps53-like, N-terminal ABC_tran_CTD PF16326.5 PVD32251.1 - 0.49 10.7 4.6 1.4 9.2 3.6 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain CC2-LZ PF16516.5 PVD32251.1 - 1.9 8.9 6.5 0.8 10.1 3.1 1.9 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RRM_1 PF00076.22 PVD32252.1 - 0.0011 18.7 0.0 0.0037 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LicD PF04991.13 PVD32252.1 - 0.06 13.5 2.6 0.1 12.7 2.6 1.4 1 0 0 1 1 1 0 LicD family RRM_occluded PF16842.5 PVD32252.1 - 0.091 12.6 0.0 1.7 8.6 0.0 2.5 2 1 0 2 2 2 0 Occluded RNA-recognition motif Ly49 PF08391.10 PVD32252.1 - 1.1 9.6 3.3 2.3 8.6 3.3 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region CRAL_TRIO PF00650.20 PVD32253.1 - 1.2e-34 119.3 0.0 1.7e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PVD32253.1 - 1.8e-08 34.6 0.0 2.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD32253.1 - 5.8e-08 32.8 0.3 2.7e-07 30.7 0.5 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain H_lectin PF09458.10 PVD32254.1 - 1.7e-06 28.1 0.3 0.0024 18.0 0.0 3.0 3 0 0 3 3 3 2 H-type lectin domain DUF1797 PF08796.10 PVD32254.1 - 0.13 12.3 1.9 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Presenilin PF01080.17 PVD32255.1 - 8.6 5.0 8.2 5 5.8 2.4 2.1 2 0 0 2 2 2 0 Presenilin PBP1_TM PF14812.6 PVD32256.1 - 0.055 13.8 0.5 0.1 13.0 0.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ig_3 PF13927.6 PVD32257.1 - 5.6e-05 23.7 0.1 8.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD32257.1 - 0.0018 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Serpentine_r_xa PF03383.15 PVD32257.1 - 0.0051 16.8 0.1 0.0067 16.4 0.1 1.1 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa DUF4064 PF13273.6 PVD32257.1 - 0.013 15.8 0.4 0.022 15.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Neurensin PF14927.6 PVD32257.1 - 0.026 14.2 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Neurensin Ig_3 PF13927.6 PVD32258.1 - 1.5e-19 70.3 0.1 5.7e-10 39.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD32258.1 - 1.6e-19 69.8 0.0 2.7e-12 46.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 PVD32258.1 - 1.1e-13 51.1 0.1 1.9e-07 31.1 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD32258.1 - 2.1e-10 40.8 0.3 0.00017 21.9 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD32258.1 - 4.7e-09 36.4 0.1 0.15 12.2 0.0 4.7 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.5 PVD32258.1 - 0.00089 19.5 0.4 3.6 7.9 0.0 3.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD32258.1 - 0.014 15.5 0.1 1.3 9.2 0.0 3.1 3 1 1 4 4 4 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD32259.1 - 2.8e-07 31.0 7.7 0.00038 21.0 0.1 2.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD32259.1 - 0.0006 19.8 0.1 0.0098 15.9 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin I-set domain DUF4064 PF13273.6 PVD32259.1 - 0.033 14.4 0.3 0.062 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) OATP PF03137.20 PVD32259.1 - 0.15 10.4 0.5 0.2 9.9 0.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 PVD32259.1 - 0.42 11.2 2.1 0.89 10.2 2.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ig_3 PF13927.6 PVD32260.1 - 0.0085 16.7 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain YrpD PF15493.6 PVD32260.1 - 0.05 13.5 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD I-set PF07679.16 PVD32260.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD32261.1 - 3.8e-20 72.3 0.4 8.9e-15 55.1 0.1 3.8 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD32261.1 - 2.5e-12 46.7 0.0 8.2e-08 32.2 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32261.1 - 1.8e-10 41.0 1.2 1.9e-09 37.7 0.1 2.6 2 1 1 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD32261.1 - 3.7e-09 36.6 0.1 0.00038 20.6 0.1 3.1 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD32261.1 - 1.2e-07 31.9 0.3 0.14 12.3 0.1 4.3 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD32261.1 - 0.00023 21.1 0.2 0.43 10.7 0.0 3.8 3 1 1 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD32261.1 - 0.012 16.0 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 PVD32261.1 - 0.013 15.9 0.0 4.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin C1-set domain Glycoprotein PF03409.15 PVD32261.1 - 0.04 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Ig_4 PF16680.5 PVD32261.1 - 0.046 14.0 0.0 0.62 10.4 0.0 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Neur_chan_LBD PF02931.23 PVD32265.1 - 2e-13 50.3 0.8 2e-13 50.3 0.8 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain CENP-O PF09496.10 PVD32265.1 - 0.00074 19.6 0.3 0.00074 19.6 0.3 2.6 1 1 1 2 2 2 1 Cenp-O kinetochore centromere component AAA_23 PF13476.6 PVD32265.1 - 0.047 14.2 1.6 0.085 13.4 1.6 1.5 1 0 0 1 1 1 0 AAA domain DUF848 PF05852.11 PVD32265.1 - 0.098 12.8 3.2 0.26 11.4 3.2 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Pinin_SDK_memA PF04696.13 PVD32265.1 - 0.9 9.6 19.7 0.028 14.5 10.4 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 PVD32265.1 - 7 5.9 8.9 12 5.1 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MBOAT PF03062.19 PVD32266.1 - 8.6e-33 114.1 7.0 8.6e-33 114.1 7.0 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CBAH PF02275.18 PVD32267.1 - 2.5e-10 40.5 0.0 4.9e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 PVD32267.1 - 1.7e-08 34.7 0.5 4e-08 33.4 0.5 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ZU5 PF00791.20 PVD32268.1 - 1.1e-07 32.1 3.2 1.1e-06 28.8 0.0 3.4 3 0 0 3 3 3 1 ZU5 domain Snf7 PF03357.21 PVD32269.1 - 9.1e-36 123.0 15.5 1.1e-35 122.8 15.5 1.1 1 0 0 1 1 1 1 Snf7 PIEZO PF15917.5 PVD32269.1 - 1.9 7.9 10.7 0.62 9.5 7.7 1.6 1 1 0 2 2 2 0 Piezo PTH2 PF01981.16 PVD32270.1 - 4.9e-36 123.6 0.0 7.2e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4035 PF13227.6 PVD32270.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Pkinase PF00069.25 PVD32271.1 - 1.6e-35 122.8 0.0 2.1e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD32271.1 - 1.1e-14 54.3 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD32271.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD32271.1 - 0.0006 18.7 0.0 0.0012 17.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD32271.1 - 0.028 14.4 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD32271.1 - 0.25 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PNTB PF02233.16 PVD32272.1 - 2.9e-187 623.2 19.6 6.7e-187 622.0 13.1 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 PVD32272.1 - 9.5e-74 247.3 0.1 2.1e-73 246.2 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PVD32272.1 - 7.4e-46 155.8 0.1 1.3e-45 155.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 PVD32272.1 - 3.8e-33 113.8 3.6 3.8e-33 113.8 3.6 3.7 4 1 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 PVD32272.1 - 0.032 13.5 0.2 0.058 12.6 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PVD32272.1 - 0.089 11.9 0.4 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 PVD32272.1 - 0.17 11.2 1.2 0.68 9.3 0.1 2.6 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Iso_dh PF00180.20 PVD32273.1 - 1.8e-78 264.2 0.0 2e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MADF_DNA_bdg PF10545.9 PVD32274.1 - 0.017 15.4 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Fringe PF02434.16 PVD32275.1 - 1.4e-12 47.6 0.2 4.8e-12 45.9 0.2 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD32275.1 - 2.4e-06 27.5 0.3 2e-05 24.5 0.3 2.2 1 1 0 1 1 1 1 Galactosyltransferase THAP PF05485.12 PVD32275.1 - 1.3e-05 26.1 0.8 3.4e-05 24.7 0.1 2.2 3 0 0 3 3 3 1 THAP domain Fringe PF02434.16 PVD32276.1 - 1.8e-15 57.1 0.1 4.8e-15 55.7 0.1 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD32276.1 - 1.2e-06 28.5 0.6 4.8e-05 23.3 0.3 2.4 2 1 1 3 3 3 1 Galactosyltransferase Glyco_trans_2_3 PF13632.6 PVD32276.1 - 0.048 13.6 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Fringe PF02434.16 PVD32277.1 - 3.4e-13 49.6 0.1 1.5e-12 47.5 0.1 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD32277.1 - 2.4e-08 34.0 0.0 1.2e-06 28.5 0.1 2.3 1 1 1 2 2 2 1 Galactosyltransferase Glyco_trans_2_3 PF13632.6 PVD32277.1 - 0.00028 20.8 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Hydrolase_6 PF13344.6 PVD32277.1 - 0.11 12.7 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NERD PF08378.11 PVD32278.1 - 0.0035 17.8 0.0 0.0097 16.4 0.0 1.8 1 0 0 1 1 1 1 Nuclease-related domain Branch PF02485.21 PVD32281.1 - 2.6e-123 410.3 0.2 2.1e-40 138.8 0.0 3.2 3 0 0 3 3 3 3 Core-2/I-Branching enzyme MTH865 PF07747.11 PVD32281.1 - 0.00062 19.5 0.2 21 5.0 0.0 3.6 3 0 0 3 3 3 0 MTH865-like family DBB PF14545.6 PVD32281.1 - 0.0031 17.5 0.1 12 5.9 0.0 3.7 4 0 0 4 4 4 1 Dof, BCAP, and BANK (DBB) motif, Hormone_2 PF00123.20 PVD32281.1 - 0.01 15.7 2.1 0.88 9.5 0.2 3.3 3 0 0 3 3 3 0 Peptide hormone LEF-9 PF05094.12 PVD32281.1 - 0.056 12.0 1.2 14 4.1 0.0 3.1 3 0 0 3 3 3 0 Late expression factor 9 (LEF-9) Ecotin PF03974.13 PVD32281.1 - 0.12 12.4 0.1 51 3.9 0.0 3.4 3 0 0 3 3 3 0 Ecotin RMMBL PF07521.12 PVD32281.1 - 0.12 12.3 1.9 3.3 7.7 0.0 3.8 5 0 0 5 5 5 0 Zn-dependent metallo-hydrolase RNA specificity domain Caskin-Pro-rich PF16907.5 PVD32281.1 - 0.16 12.5 0.1 22 5.6 0.0 2.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins RPA_interact_C PF14768.6 PVD32281.1 - 0.16 12.5 2.6 59 4.3 0.1 3.4 3 0 0 3 3 3 0 Replication protein A interacting C-terminal Branch PF02485.21 PVD32282.1 - 4.6e-41 141.0 0.0 7.3e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme ADAM_CR_2 PF17771.1 PVD32284.1 - 4.2e-12 46.4 2.3 4.2e-12 46.4 2.3 2.6 3 0 0 3 3 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 PVD32284.1 - 6.9e-11 42.4 0.0 1.8e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD32284.1 - 1.6e-07 31.7 0.1 2.9e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 SAM_1 PF00536.30 PVD32284.1 - 3.8e-07 30.4 0.3 1.1e-06 29.0 0.0 1.9 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) Reprolysin_3 PF13582.6 PVD32284.1 - 5.1e-06 27.0 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD32284.1 - 8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD32284.1 - 0.0006 19.5 0.2 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SAM_2 PF07647.17 PVD32284.1 - 0.0072 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CABIT PF12736.7 PVD32284.1 - 0.011 15.0 0.2 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, Pep_M12B_propep PF01562.19 PVD32284.1 - 0.014 15.6 0.1 0.11 12.8 0.2 2.2 2 0 0 2 2 2 0 Reprolysin family propeptide PRIMA1 PF16101.5 PVD32284.1 - 0.049 13.7 2.1 0.17 11.9 2.1 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4939 PF16297.5 PVD32285.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) SAM_1 PF00536.30 PVD32286.1 - 1.4e-05 25.4 0.0 2.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD32286.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CABIT PF12736.7 PVD32286.1 - 0.029 13.7 0.1 0.064 12.5 0.1 1.6 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 PVD32287.1 - 4.9e-13 49.3 0.1 5.7e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD32287.1 - 3e-09 36.9 0.1 0.0038 17.3 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DNA_pol_alpha_N PF12254.8 PVD32287.1 - 0.015 15.3 0.2 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Vint PF14623.6 PVD32287.1 - 0.028 14.2 0.1 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Hint-domain HTH_37 PF13744.6 PVD32287.1 - 0.046 13.7 0.1 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DAHP_snth_FXD PF18152.1 PVD32287.1 - 0.15 11.9 0.0 31 4.5 0.0 2.7 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain SAM_1 PF00536.30 PVD32288.1 - 1.2e-05 25.7 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD32288.1 - 0.0057 16.7 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Amnionless PF14828.6 PVD32290.1 - 2.6e-84 283.7 0.0 3e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Amnionless DUF5305 PF17231.2 PVD32290.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Podoplanin PF05808.11 PVD32290.1 - 0.043 13.9 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 Podoplanin ThiF PF00899.21 PVD32291.1 - 7.9e-63 212.1 0.0 1.1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 PVD32291.1 - 0.00019 21.9 0.0 0.00071 20.1 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_3 PF01494.19 PVD32291.1 - 0.01 15.1 0.2 0.014 14.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 PVD32291.1 - 0.016 15.3 0.3 0.15 12.1 0.3 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 PVD32291.1 - 0.074 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 PVD32291.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 PVD32291.1 - 0.18 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD32291.1 - 0.18 11.3 1.2 0.32 10.5 1.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Symplekin_C PF12295.8 PVD32292.1 - 4.5e-71 238.8 6.2 1.3e-70 237.3 6.2 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 PVD32292.1 - 8.1e-55 185.9 4.3 8.1e-55 185.9 4.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Nop53 PF07767.11 PVD32292.1 - 2.5e-44 152.3 23.1 2.5e-44 152.3 23.1 2.5 1 1 1 2 2 2 1 Nop53 (60S ribosomal biogenesis) Beta_helix PF13229.6 PVD32293.1 - 8e-83 276.0 63.5 1.3e-27 96.6 17.7 4.3 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 PVD32293.1 - 2.1e-41 141.8 42.5 1e-13 51.1 4.7 4.4 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 PVD32293.1 - 6e-14 51.7 0.2 1.4e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD32293.1 - 7.7e-10 38.4 0.2 1.9e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain zf-UBR PF02207.20 PVD32293.1 - 5.4e-06 26.5 10.6 1.4e-05 25.2 10.6 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) F-box_4 PF15966.5 PVD32293.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 F-box EF-hand_7 PF13499.6 PVD32294.1 - 5e-14 52.5 3.4 1.8e-09 37.9 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD32294.1 - 9.6e-13 46.7 8.0 9.6e-06 24.8 2.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD32294.1 - 1.1e-10 41.1 5.5 2.3e-07 30.6 0.5 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD32294.1 - 6.6e-10 38.1 5.5 0.0022 17.8 1.7 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD32294.1 - 0.0012 18.2 5.2 0.0033 16.9 0.6 3.3 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 PVD32294.1 - 0.0039 17.1 0.2 1.1 9.3 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PVD32294.1 - 0.0063 16.8 0.4 0.019 15.3 0.2 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region ERG4_ERG24 PF01222.17 PVD32295.1 - 9.3e-144 479.4 10.8 1.7e-143 478.5 10.8 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 PVD32295.1 - 0.0003 20.4 0.3 0.0015 18.1 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ORC6 PF05460.13 PVD32295.1 - 0.013 14.7 4.9 0.017 14.4 4.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ICMT PF04140.14 PVD32295.1 - 0.52 10.8 0.0 0.52 10.8 0.0 2.7 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3671 PF12420.8 PVD32295.1 - 2.5 8.2 5.0 1.6 8.8 0.6 3.0 3 2 0 3 3 3 0 Protein of unknown function BPS1 PF05633.11 PVD32295.1 - 8.8 5.2 7.0 13 4.7 7.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related Radial_spoke PF04712.12 PVD32296.1 - 2.2e-190 633.8 11.8 2.2e-190 633.8 11.8 1.5 1 1 1 2 2 2 1 Radial spokehead-like protein WW PF00397.26 PVD32297.1 - 1.1e-16 60.6 12.4 3.2e-09 36.7 2.2 3.0 3 0 0 3 3 3 2 WW domain O-antigen_lig PF13425.6 PVD32297.1 - 0.025 13.4 0.5 0.041 12.7 0.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4200 PF13863.6 PVD32298.1 - 1.3e-27 96.5 30.1 1.3e-27 96.5 30.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) TACC_C PF05010.14 PVD32298.1 - 0.00087 19.1 32.7 0.082 12.7 20.4 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 PVD32298.1 - 0.0081 16.2 19.1 0.035 14.2 2.3 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 PVD32298.1 - 0.059 13.6 22.7 0.24 11.6 2.7 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain TraF_2 PF13729.6 PVD32298.1 - 0.25 10.7 1.7 2.1 7.7 0.1 2.3 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein PDE4_UCR PF18100.1 PVD32298.1 - 0.48 11.1 11.4 3.9 8.2 5.3 2.9 2 1 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) ATG16 PF08614.11 PVD32298.1 - 0.5 10.5 29.7 0.067 13.4 14.4 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 PVD32298.1 - 1.7 8.7 36.3 2.6 8.1 17.9 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CP12 PF02672.15 PVD32298.1 - 2 9.3 13.9 7.2 7.4 2.8 3.7 2 1 1 3 3 3 0 CP12 domain FapA PF03961.13 PVD32298.1 - 2 6.9 23.1 2.9 6.4 12.4 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4326 PF14216.6 PVD32298.1 - 3.1 8.6 5.8 2.4 8.9 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) DUF5329 PF17263.2 PVD32298.1 - 4.5 7.5 13.4 0.55 10.5 4.6 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5329) DUF4192 PF13830.6 PVD32298.1 - 5.9 6.9 6.3 6.3 6.8 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Atg14 PF10186.9 PVD32298.1 - 6.4 5.8 30.4 3.2 6.8 16.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 PVD32298.1 - 7.6 5.3 35.6 2.4 7.0 6.1 2.3 1 1 2 3 3 3 0 Spc7 kinetochore protein PspB PF06667.12 PVD32298.1 - 8.1 6.6 16.2 3.5 7.8 1.5 3.6 3 0 0 3 3 3 0 Phage shock protein B DUF4140 PF13600.6 PVD32298.1 - 8.8 6.8 17.1 16 6.0 2.2 3.8 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) DUF4633 PF15464.6 PVD32298.1 - 9.6 6.4 11.2 3.3 7.9 7.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4633) E3_UbLigase_RBR PF18091.1 PVD32299.1 - 0.067 13.3 0.5 0.22 11.7 0.5 1.9 1 1 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain Img2 PF05046.14 PVD32300.1 - 0.094 13.0 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_H2_suC PF08615.11 PVD32301.1 - 1.3e-16 61.1 0.1 8.3e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) KSHV_K8 PF07188.11 PVD32301.1 - 0.081 12.3 0.1 0.87 8.9 0.0 2.2 2 1 1 3 3 3 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein UIM PF02809.20 PVD32302.1 - 0.0022 17.8 3.5 0.0022 17.8 3.5 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif DUF1003 PF06210.11 PVD32303.1 - 1.4 9.0 3.6 2.6 8.2 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DAO PF01266.24 PVD32304.1 - 1.6e-63 215.4 0.0 2.2e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PVD32304.1 - 0.00028 20.2 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PVD32304.1 - 0.00055 20.1 0.1 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PVD32304.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 PVD32304.1 - 0.003 16.2 0.0 0.012 14.1 0.0 1.9 2 1 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 PVD32304.1 - 0.022 14.0 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PVD32304.1 - 0.032 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 PVD32304.1 - 0.11 11.5 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 PVD32304.1 - 0.14 12.8 0.1 2.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PVD32304.1 - 0.25 10.2 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UPF0020 PF01170.18 PVD32305.1 - 1.7e-25 89.9 0.0 9.6e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 PVD32305.1 - 1.2e-15 57.6 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD32305.1 - 5.9e-14 52.5 0.0 1.4e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD32305.1 - 2e-11 43.7 0.0 4e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PVD32305.1 - 4.7e-11 43.2 0.0 1.2e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD32305.1 - 2.8e-08 33.5 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 PVD32305.1 - 7.4e-06 25.8 0.0 0.0018 18.0 0.0 2.6 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 PVD32305.1 - 0.00025 20.4 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 PVD32305.1 - 0.0018 19.0 0.2 0.0066 17.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD32305.1 - 0.006 16.1 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase AviRa PF11599.8 PVD32305.1 - 0.011 15.2 0.0 3.5 7.0 0.0 2.3 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_33 PF10017.9 PVD32305.1 - 0.013 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CMAS PF02353.20 PVD32305.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Med12 PF09497.10 PVD32306.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 Sde2_N_Ubi PF13019.6 PVD32307.1 - 1.1e-22 80.6 2.2 3.3e-22 79.1 2.2 1.8 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DUF4228 PF14009.6 PVD32307.1 - 0.00039 20.8 1.2 0.00039 20.8 1.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4228) Linocin_M18 PF04454.12 PVD32307.1 - 0.0078 15.5 1.0 0.15 11.3 0.2 2.3 2 0 0 2 2 2 1 Encapsulating protein for peroxidase pRN1_helical PF13010.6 PVD32307.1 - 0.2 11.6 6.0 0.16 11.9 3.4 2.0 1 1 2 3 3 3 0 Primase helical domain DUF5333 PF17267.2 PVD32307.1 - 4.4 7.5 8.3 18 5.5 0.6 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5333) Forkhead PF00250.18 PVD32310.1 - 2.1e-37 127.3 0.1 4.6e-37 126.2 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.12 PVD32310.1 - 8.9e-12 45.8 51.5 8.9e-12 45.8 51.5 2.5 2 0 0 2 2 2 1 Forkhead N-terminal region HNF_C PF09354.10 PVD32310.1 - 1.1e-07 32.7 4.8 1.1e-07 32.7 4.8 4.2 2 1 1 3 3 3 1 HNF3 C-terminal domain Sporozoite_P67 PF05642.11 PVD32310.1 - 7.8 4.4 10.5 20 3.1 10.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_M8 PF01457.16 PVD32311.1 - 5e-33 114.6 1.1 8.2e-33 113.9 1.1 1.2 1 0 0 1 1 1 1 Leishmanolysin ThiF PF00899.21 PVD32311.1 - 6e-30 104.4 0.0 9.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family Codanin-1_C PF15296.6 PVD32312.1 - 1.4e-27 96.2 0.2 1.4e-27 96.2 0.2 3.4 3 0 0 3 3 3 1 Codanin-1 C-terminus Ras PF00071.22 PVD32313.1 - 1.3e-48 164.6 0.3 4e-36 124.1 0.1 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PVD32313.1 - 2.7e-20 72.8 0.4 2.6e-11 43.8 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32313.1 - 1.3e-08 34.5 0.1 2.4e-05 23.9 0.1 3.1 2 1 1 3 3 3 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD32313.1 - 9.2e-08 32.2 0.0 2.8e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase zf-Sec23_Sec24 PF04810.15 PVD32313.1 - 4.4e-07 29.8 0.2 9.8e-07 28.7 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger GTP_EFTU PF00009.27 PVD32313.1 - 5e-07 29.5 0.2 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain VWA_2 PF13519.6 PVD32313.1 - 2.3e-06 28.2 0.0 0.032 14.9 0.0 3.3 1 1 1 2 2 2 2 von Willebrand factor type A domain Sec23_BS PF08033.12 PVD32313.1 - 0.00033 21.3 0.1 0.00097 19.8 0.0 1.9 2 0 0 2 2 1 1 Sec23/Sec24 beta-sandwich domain FeoB_N PF02421.18 PVD32313.1 - 0.00068 19.2 1.1 0.0045 16.5 0.0 2.8 4 0 0 4 4 4 1 Ferrous iron transport protein B Sec23_trunk PF04811.15 PVD32313.1 - 0.021 14.4 0.3 2.9 7.4 0.0 3.2 2 1 0 2 2 2 0 Sec23/Sec24 trunk domain DUF190 PF02641.15 PVD32313.1 - 0.06 13.7 0.1 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 Ras PF00071.22 PVD32314.1 - 3.9e-40 137.1 0.0 4.8e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32314.1 - 1.6e-20 73.5 0.0 2.2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32314.1 - 2.8e-05 23.6 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD32314.1 - 0.0028 17.2 0.1 0.036 13.6 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD32314.1 - 0.029 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.22 PVD32315.1 - 6.1e-47 159.2 0.0 7.2e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32315.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32315.1 - 4.4e-06 26.2 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD32315.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 PVD32315.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SDF PF00375.18 PVD32316.1 - 9.2e-65 219.2 19.0 9.2e-65 219.2 19.0 1.5 2 0 0 2 2 2 1 Sodium:dicarboxylate symporter family SLC35F PF06027.12 PVD32318.1 - 2e-06 27.6 3.0 2e-06 27.6 3.0 2.1 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 PVD32318.1 - 1.2e-05 24.5 4.9 1.2e-05 24.5 4.9 2.0 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 PVD32318.1 - 0.00023 20.5 2.2 0.00023 20.5 2.2 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 PVD32318.1 - 0.00031 20.9 16.0 0.00059 20.0 1.1 2.9 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 PVD32318.1 - 0.00076 18.9 1.5 0.001 18.5 1.5 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 PVD32318.1 - 0.001 18.3 2.0 0.0017 17.6 2.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PVD32318.1 - 1.9 7.6 12.3 4.1 6.5 12.3 1.6 1 1 0 1 1 1 0 UAA transporter family Hyd_WA PF06462.12 PVD32319.1 - 4.5e-33 112.9 34.2 1.7e-06 27.9 0.5 8.5 8 0 0 8 8 8 6 Propeller ANAPC4_WD40 PF12894.7 PVD32319.1 - 0.081 13.2 0.7 1.5 9.2 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Na_Pi_cotrans PF02690.15 PVD32320.1 - 1.8e-23 83.2 9.5 4.4e-15 56.0 2.0 3.0 2 0 0 2 2 2 2 Na+/Pi-cotransporter LRR_4 PF12799.7 PVD32321.1 - 3.1e-24 84.6 43.3 1.8e-06 28.2 1.9 4.4 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD32321.1 - 1.8e-20 72.5 34.4 4.2e-10 39.2 7.2 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 PVD32321.1 - 7.1e-08 32.0 18.5 0.21 12.3 0.0 7.2 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD32321.1 - 5.6e-05 22.9 24.8 0.16 12.1 0.3 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 PVD32321.1 - 0.00032 20.3 6.6 0.041 13.4 0.2 2.2 1 1 0 2 2 2 2 Leucine-rich repeat RsmF_methylt_CI PF17126.5 PVD32321.1 - 0.00088 19.3 0.0 0.91 9.6 0.0 3.3 3 0 0 3 3 3 1 RsmF rRNA methyltransferase first C-terminal domain LRR_2 PF07723.13 PVD32321.1 - 0.14 12.9 6.3 21 6.0 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat NTPase_1 PF03266.15 PVD32322.1 - 1.1e-51 175.0 0.0 1.4e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 NTPase AAA PF00004.29 PVD32322.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PVD32322.1 - 0.016 15.1 0.1 0.046 13.7 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 PVD32322.1 - 0.03 14.4 0.0 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD32322.1 - 0.063 13.7 0.1 0.098 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 PVD32322.1 - 0.11 12.5 0.0 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PVD32322.1 - 0.15 12.5 0.0 0.62 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Metallophos PF00149.28 PVD32323.1 - 2.5e-37 129.4 0.3 6e-37 128.1 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 PVD32323.1 - 4.9e-33 113.3 2.3 5.5e-33 113.1 0.7 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 PVD32323.1 - 1.9e-13 49.6 8.5 1.4e-05 24.7 0.3 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD32323.1 - 1.3e-11 43.7 9.9 0.001 19.0 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD32323.1 - 3.4e-06 27.1 0.1 7.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32323.1 - 6.9e-06 25.9 4.8 0.016 15.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD32323.1 - 8.6e-06 25.3 5.0 0.33 10.7 0.2 3.4 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 PVD32323.1 - 0.00013 22.5 0.4 1.7 9.7 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD32323.1 - 0.00053 20.6 3.0 0.15 12.7 0.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD32323.1 - 0.0091 16.0 0.2 3.2 8.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD32323.1 - 0.01 16.2 3.4 0.83 10.2 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD32323.1 - 0.01 16.1 1.6 4.4 7.7 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD32323.1 - 0.06 14.0 1.2 7.2 7.5 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD32323.1 - 0.061 13.8 1.0 7.7 7.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat BID PF06393.11 PVD32323.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF807 PF05660.11 PVD32323.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) S10_plectin PF03501.15 PVD32323.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain MIT PF04212.18 PVD32323.1 - 0.3 11.2 3.1 5.9 7.0 0.5 2.8 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ependymin PF00811.18 PVD32324.1 - 5.4e-07 29.9 0.3 1.5e-06 28.4 0.3 1.8 1 1 0 1 1 1 1 Ependymin I-set PF07679.16 PVD32325.1 - 2.2e-14 53.3 0.0 3.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD32325.1 - 3.8e-13 49.9 0.0 8.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD32325.1 - 2.1e-10 40.8 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD32325.1 - 3.8e-08 33.4 0.0 7.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain EGF PF00008.27 PVD32325.1 - 1e-05 25.7 6.7 2.3e-05 24.6 6.7 1.6 1 0 0 1 1 1 1 EGF-like domain V-set PF07686.17 PVD32325.1 - 5.8e-05 23.2 0.0 0.0011 19.2 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain EGF_2 PF07974.13 PVD32325.1 - 0.02 15.3 7.1 0.037 14.4 7.1 1.5 1 0 0 1 1 1 0 EGF-like domain Ig_4 PF16680.5 PVD32325.1 - 0.04 14.2 0.0 0.17 12.1 0.0 2.0 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD32325.1 - 0.051 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain hEGF PF12661.7 PVD32325.1 - 0.1 13.3 3.7 0.1 13.3 3.7 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF Ldr_toxin PF13940.6 PVD32326.1 - 0.0084 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system Reticulon PF02453.17 PVD32328.1 - 6.8e-36 123.6 9.1 1.1e-35 122.9 9.1 1.3 1 0 0 1 1 1 1 Reticulon DUF2547 PF10818.8 PVD32328.1 - 0.031 15.2 0.1 0.085 13.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) SecD-TM1 PF13721.6 PVD32328.1 - 0.051 14.0 0.2 0.13 12.7 0.2 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region sCache_2 PF17200.4 PVD32328.1 - 0.058 13.3 0.2 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 Single Cache domain 2 BAH PF01426.18 PVD32330.1 - 3.1e-12 46.4 0.3 8.2e-11 41.8 0.3 2.5 1 1 0 1 1 1 1 BAH domain RR_TM4-6 PF06459.12 PVD32330.1 - 4.2 7.1 9.8 6.3 6.5 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PVD32330.1 - 4.3 6.0 4.8 5.7 5.6 4.8 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 PVD32330.1 - 4.7 5.6 12.0 6.7 5.1 12.0 1.1 1 0 0 1 1 1 0 Macoilin family BTB_2 PF02214.22 PVD32331.1 - 3.1e-23 81.9 0.0 6.2e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain UPF0300 PF08594.10 PVD32331.1 - 0.37 10.1 2.7 0.78 9.0 0.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0300) SRP54 PF00448.22 PVD32332.1 - 3.2e-79 265.1 0.1 7.1e-79 264.0 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PVD32332.1 - 1.1e-28 99.7 2.3 1.1e-28 99.7 2.3 3.5 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 PVD32332.1 - 2e-19 69.6 1.1 6.8e-19 67.9 1.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 PVD32332.1 - 4.8e-07 29.5 0.6 4.4e-06 26.4 0.6 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 PVD32332.1 - 1.6e-05 25.0 0.0 6.9e-05 22.9 0.0 2.1 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 PVD32332.1 - 1.8e-05 24.9 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PVD32332.1 - 0.00017 22.0 0.5 0.00077 19.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 PVD32332.1 - 0.00025 21.5 3.0 0.012 16.1 0.1 3.7 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 PVD32332.1 - 0.00033 20.2 0.8 0.23 10.9 0.8 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ResIII PF04851.15 PVD32332.1 - 0.00034 20.6 0.5 0.0021 18.1 0.5 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2209 PF09974.9 PVD32332.1 - 0.0017 18.7 0.2 0.0046 17.3 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_16 PF13191.6 PVD32332.1 - 0.0021 18.5 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 PVD32332.1 - 0.0022 17.0 0.0 0.021 13.8 0.0 2.4 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 PVD32332.1 - 0.0027 17.5 0.3 2.9 7.6 0.1 2.6 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 PVD32332.1 - 0.003 17.6 0.2 0.023 14.8 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase APS_kinase PF01583.20 PVD32332.1 - 0.0042 17.0 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 PVD32332.1 - 0.0073 16.0 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.6 PVD32332.1 - 0.013 15.4 0.0 0.06 13.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 PVD32332.1 - 0.019 15.5 0.1 0.081 13.5 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_22 PF13401.6 PVD32332.1 - 0.021 15.1 0.7 0.13 12.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 PVD32332.1 - 0.026 14.4 0.2 0.074 13.0 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 PVD32332.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 PVD32332.1 - 0.034 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 PVD32332.1 - 0.045 14.0 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PVD32332.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 PVD32332.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.17 PVD32332.1 - 0.068 13.0 0.3 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 PVD32332.1 - 0.082 12.0 0.2 0.78 8.8 0.0 2.2 2 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 PVD32332.1 - 0.083 12.6 0.3 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.15 PVD32332.1 - 0.096 11.8 0.0 0.096 11.8 0.0 3.1 3 1 0 3 3 3 0 Anion-transporting ATPase Peptidase_C65 PF10275.9 PVD32333.1 - 1.5e-77 260.4 0.1 2.2e-77 259.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Acyltransf_C PF16076.5 PVD32333.1 - 1.6e-16 60.1 1.5 3.2e-16 59.2 0.5 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 PVD32333.1 - 1.4e-10 40.9 0.1 4.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase SIX1_SD PF16878.5 PVD32334.1 - 6.8e-49 165.0 1.7 1.1e-47 161.2 0.2 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 PVD32334.1 - 2.9e-15 55.8 2.2 7.1e-15 54.6 0.8 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PVD32334.1 - 1.2e-09 37.9 0.6 2.3e-09 37.0 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 PVD32334.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 PVD32334.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix ATAD4 PF15321.6 PVD32335.1 - 0.029 15.7 0.1 0.038 15.3 0.1 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 NUDIX PF00293.28 PVD32336.1 - 0.0019 18.2 0.0 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain F-box-like PF12937.7 PVD32337.1 - 6.9e-12 45.1 0.7 6.9e-12 45.1 0.7 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD32337.1 - 0.0059 16.5 0.8 0.0059 16.5 0.8 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 PVD32337.1 - 0.28 11.7 10.4 45 4.7 0.5 6.0 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 PVD32338.1 - 2.8e-06 26.9 0.6 0.064 13.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD32338.1 - 6.8e-06 26.1 0.1 1.9e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD32338.1 - 2.2e-05 24.9 0.0 5.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD32338.1 - 6.2e-05 22.8 0.1 0.058 13.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32338.1 - 0.00014 21.8 0.5 0.072 13.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF848 PF05852.11 PVD32338.1 - 0.0083 16.2 1.1 0.014 15.5 1.1 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) TPR_20 PF14561.6 PVD32338.1 - 0.0099 16.2 0.2 0.084 13.2 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD32338.1 - 0.014 15.4 0.0 5.4 7.3 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD32338.1 - 0.026 15.3 0.0 3.3 8.8 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD32338.1 - 0.031 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Ntox33 PF15533.6 PVD32338.1 - 0.031 14.7 0.8 0.095 13.2 0.0 2.2 3 0 0 3 3 3 0 Bacterial toxin 33 HR1 PF02185.16 PVD32338.1 - 0.038 14.1 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 Hr1 repeat TPR_6 PF13174.6 PVD32338.1 - 0.047 14.4 0.0 0.15 12.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD32338.1 - 0.053 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 PVD32338.1 - 0.061 13.3 0.4 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Halogen_Hydrol PF10112.9 PVD32338.1 - 0.25 11.3 1.7 0.41 10.6 0.6 1.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CSN8_PSD8_EIF3K PF10075.9 PVD32339.1 - 1.7e-30 105.9 0.5 2.6e-30 105.3 0.5 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 PVD32339.1 - 0.0065 17.0 0.2 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.16 PVD32339.1 - 0.012 15.0 0.5 0.015 14.7 0.5 1.2 1 0 0 1 1 1 0 SAC3/GANP family Homeodomain PF00046.29 PVD32340.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain Lig_chan-Glu_bd PF10613.9 PVD32341.1 - 6.3e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD32341.1 - 1.2e-07 31.6 1.1 5.1e-07 29.6 0.5 2.2 2 1 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD32341.1 - 6.8e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Patched PF02460.18 PVD32342.1 - 0.019 13.1 6.6 0.027 12.6 6.6 1.2 1 0 0 1 1 1 0 Patched family DUF3760 PF12586.8 PVD32342.1 - 0.023 14.9 0.4 0.042 14.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) MMPL PF03176.15 PVD32342.1 - 0.027 13.4 4.2 0.037 13.0 4.2 1.1 1 0 0 1 1 1 0 MMPL family Maff2 PF12750.7 PVD32342.1 - 0.028 14.2 1.4 0.38 10.6 0.1 2.4 1 1 1 2 2 2 0 Maff2 family Phage_holin_3_6 PF07332.11 PVD32342.1 - 0.068 13.2 3.8 0.14 12.2 3.8 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Sterol-sensing PF12349.8 PVD32343.1 - 3.9e-15 56.0 16.1 9.5e-15 54.8 16.1 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 PVD32343.1 - 6.3e-12 44.4 16.2 9.6e-12 43.8 15.7 1.4 1 1 0 1 1 1 1 Patched family MMPL PF03176.15 PVD32343.1 - 0.0003 19.8 5.5 0.00058 18.9 5.5 1.4 1 0 0 1 1 1 1 MMPL family Pox_I5 PF04713.12 PVD32343.1 - 0.1 12.6 3.3 0.2 11.7 1.3 2.6 2 0 0 2 2 2 0 Poxvirus protein I5 Auto_anti-p27 PF06677.12 PVD32344.1 - 1.8e-15 56.8 3.1 3e-15 56.1 3.1 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRN7 PF11781.8 PVD32344.1 - 0.34 10.6 1.9 2.1 8.1 1.9 2.0 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nucleoporin_C PF03177.14 PVD32345.1 - 7.9e-21 74.4 14.4 1.2e-20 73.8 9.2 3.3 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 PVD32345.1 - 4.6e-20 71.8 0.0 7.6e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DUF3776 PF12618.8 PVD32346.1 - 0.1 13.1 7.1 2.7 8.6 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3776) AAA PF00004.29 PVD32347.1 - 6.2e-44 149.6 0.2 5e-43 146.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PVD32347.1 - 4e-10 39.5 0.1 2.2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PVD32347.1 - 4.3e-10 39.2 0.1 1e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 PVD32347.1 - 9.6e-09 35.6 0.1 3.7e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PVD32347.1 - 1.2e-07 31.8 0.1 4.2e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD32347.1 - 2e-05 25.1 0.2 0.0062 16.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 PVD32347.1 - 0.00014 21.1 0.2 0.00058 19.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 PVD32347.1 - 0.00016 21.5 0.0 0.0006 19.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD32347.1 - 0.00025 21.3 0.6 0.049 13.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 PVD32347.1 - 0.00029 20.8 0.3 0.15 12.0 0.0 3.2 3 0 0 3 3 3 1 NTPase Mg_chelatase PF01078.21 PVD32347.1 - 0.00072 19.0 0.1 0.0017 17.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PVD32347.1 - 0.00086 19.4 0.1 0.0069 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PVD32347.1 - 0.00087 19.7 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 PVD32347.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD32347.1 - 0.0011 19.1 0.0 0.0033 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD32347.1 - 0.0013 19.3 0.0 0.013 16.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 PVD32347.1 - 0.0014 18.4 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AFG1_ATPase PF03969.16 PVD32347.1 - 0.0029 16.5 0.1 0.6 8.9 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase TIP49 PF06068.13 PVD32347.1 - 0.0044 16.3 0.0 0.0091 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 PVD32347.1 - 0.012 15.3 0.2 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 PVD32347.1 - 0.012 15.5 0.2 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 PVD32347.1 - 0.037 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 PVD32347.1 - 0.04 13.4 0.1 0.29 10.6 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PVD32347.1 - 0.057 13.3 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 PVD32347.1 - 0.07 12.5 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 PVD32347.1 - 0.075 13.6 0.0 0.35 11.4 0.0 2.2 3 0 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.12 PVD32347.1 - 0.085 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 PVD32347.1 - 0.14 11.7 2.6 0.26 10.8 0.2 2.3 2 1 1 3 3 3 0 AAA domain TIR_2 PF13676.6 PVD32348.1 - 4.7e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 TIR domain C1q PF00386.21 PVD32348.1 - 0.1 12.8 0.1 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 C1q domain DUF1484 PF07363.11 PVD32348.1 - 0.76 10.8 3.0 12 7.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) TIR_2 PF13676.6 PVD32349.1 - 3.3e-32 111.6 0.4 4.9e-19 69.1 0.1 2.3 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 PVD32349.1 - 2.5e-20 73.0 0.7 5.5e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 TIR domain TIR-like PF10137.9 PVD32349.1 - 0.0014 18.6 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 Predicted nucleotide-binding protein containing TIR-like domain DUF1863 PF08937.11 PVD32349.1 - 0.14 12.5 0.4 2.6 8.4 0.0 2.5 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Ras PF00071.22 PVD32350.1 - 2.5e-16 59.7 0.0 3.1e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32350.1 - 0.0078 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD32352.1 - 7.8e-40 136.1 0.0 8.9e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32352.1 - 4.7e-15 55.9 0.0 7.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32352.1 - 0.00019 20.9 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family baeRF_family3 PF18845.1 PVD32352.1 - 0.11 12.7 0.0 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 HELP PF03451.14 PVD32353.1 - 3.3e-33 113.3 0.2 7.7e-33 112.2 0.2 1.7 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 PVD32353.1 - 1.9e-32 110.8 25.3 0.0006 20.6 0.0 10.0 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32353.1 - 3.7e-12 46.4 0.0 0.0014 18.9 0.0 7.0 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD32353.1 - 0.0013 17.7 0.2 0.023 13.7 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Fib_alpha PF08702.10 PVD32353.1 - 0.011 15.9 0.4 0.019 15.1 0.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SdiA-regulated PF06977.11 PVD32353.1 - 0.041 13.1 0.0 0.096 11.9 0.0 1.5 1 0 0 1 1 1 0 SdiA-regulated PKcGMP_CC PF16808.5 PVD32353.1 - 0.066 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase fn3 PF00041.21 PVD32354.1 - 4.4e-127 414.7 66.9 3e-08 33.9 0.1 24.0 23 2 0 23 23 22 20 Fibronectin type III domain Laminin_EGF PF00053.24 PVD32354.1 - 2.8e-54 181.0 210.6 3.5e-08 33.5 13.4 11.1 11 0 0 11 11 9 9 Laminin EGF domain Laminin_G_2 PF02210.24 PVD32354.1 - 2.4e-28 99.3 2.7 2.2e-13 50.9 0.6 4.3 3 1 1 4 4 4 3 Laminin G domain Laminin_N PF00055.17 PVD32354.1 - 2.2e-26 92.9 0.0 2.2e-26 92.9 0.0 5.1 6 0 0 6 6 2 2 Laminin N-terminal (Domain VI) Laminin_G_1 PF00054.23 PVD32354.1 - 9.8e-24 84.0 0.2 1.5e-09 38.2 0.3 3.8 2 1 1 3 3 3 3 Laminin G domain Pur_ac_phosph_N PF16656.5 PVD32354.1 - 1.8e-17 63.7 59.7 0.18 12.4 0.1 20.5 18 5 0 18 18 18 5 Purple acid Phosphatase, N-terminal domain ChitinaseA_N PF08329.10 PVD32354.1 - 1.2e-16 60.5 25.1 0.37 10.5 0.0 12.2 10 2 2 12 12 12 7 Chitinase A, N-terminal domain Laminin_G_3 PF13385.6 PVD32354.1 - 8.8e-14 51.9 6.9 1.8e-10 41.2 1.2 3.4 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily fn3_2 PF16893.5 PVD32354.1 - 1.3e-05 25.2 15.5 0.69 10.1 0.0 8.7 10 0 0 10 10 9 2 Fibronectin type III domain PTP_tm PF18861.1 PVD32354.1 - 0.031 14.3 0.7 3.9 7.4 0.0 4.1 4 0 0 4 4 4 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J F5_F8_type_C PF00754.25 PVD32354.1 - 0.041 14.0 1.3 2.8 8.1 0.0 3.0 2 0 0 2 2 2 0 F5/8 type C domain RGI_lyase PF18370.1 PVD32354.1 - 0.045 14.0 2.0 33 4.9 0.0 4.2 4 0 0 4 4 3 0 Rhamnogalacturonan I lyases beta-sheet domain PhoD_N PF16655.5 PVD32354.1 - 2.3 8.8 6.5 2.1e+02 2.5 0.0 6.2 7 0 0 7 7 7 0 PhoD-like phosphatase, N-terminal domain SusE PF14292.6 PVD32354.1 - 3.4 7.9 13.7 10 6.4 0.1 6.2 7 0 0 7 7 7 0 SusE outer membrane protein fn3 PF00041.21 PVD32355.1 - 4.2e-24 84.7 14.1 2.2e-08 34.3 1.8 5.3 4 2 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD32355.1 - 0.00011 22.7 18.9 0.005 17.4 5.0 5.0 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain ChitinaseA_N PF08329.10 PVD32355.1 - 0.00016 21.4 0.5 1.9 8.1 0.0 3.2 3 0 0 3 3 3 3 Chitinase A, N-terminal domain DUF2369 PF10179.9 PVD32355.1 - 0.0012 19.1 0.4 0.22 11.9 0.0 3.4 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 PVD32355.1 - 0.0026 17.9 2.7 19 5.5 0.1 4.2 4 1 0 4 4 4 2 Fibronectin type III domain PhoD_N PF16655.5 PVD32355.1 - 0.0065 17.0 3.6 1.6 9.4 1.0 3.3 4 0 0 4 4 4 2 PhoD-like phosphatase, N-terminal domain Big_10 PF17964.1 PVD32355.1 - 0.041 13.9 8.4 3.2 7.7 0.0 3.3 2 1 0 3 3 3 0 Bacterial Ig domain fn3 PF00041.21 PVD32356.1 - 1.3e-14 54.3 0.1 1.7e-09 37.9 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD32356.1 - 0.0081 16.7 0.0 0.2 12.2 0.1 2.5 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF11 PF01345.18 PVD32356.1 - 0.035 14.4 1.8 0.33 11.3 0.9 2.9 1 1 1 2 2 2 0 Domain of unknown function DUF11 fn3 PF00041.21 PVD32357.1 - 4.6e-11 42.9 0.2 0.008 16.5 0.0 4.9 4 2 0 4 4 4 3 Fibronectin type III domain DAG1 PF05454.11 PVD32357.1 - 0.0011 18.4 1.0 0.0013 18.2 0.1 1.5 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) UPF0370 PF13980.6 PVD32357.1 - 0.0027 17.7 0.1 0.0057 16.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) TMEM52 PF14979.6 PVD32357.1 - 0.0097 15.8 0.1 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 Transmembrane 52 Ion_trans PF00520.31 PVD32357.1 - 0.012 14.8 0.3 0.021 14.1 0.3 1.3 1 0 0 1 1 1 0 Ion transport protein ChitinaseA_N PF08329.10 PVD32357.1 - 0.014 15.0 0.2 0.03 14.0 0.2 1.6 1 1 0 1 1 1 0 Chitinase A, N-terminal domain Hum_adeno_E3A PF05393.11 PVD32357.1 - 0.019 14.9 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PMP1_2 PF08114.11 PVD32357.1 - 0.022 14.5 5.3 0.43 10.4 5.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family Herpes_gE PF02480.16 PVD32357.1 - 0.026 13.3 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E LSR PF05624.14 PVD32357.1 - 0.32 11.0 2.1 0.87 9.6 2.1 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) CiPC PF15800.5 PVD32359.1 - 2.2e-11 44.1 5.6 2.2e-11 44.1 5.6 2.2 1 1 0 1 1 1 1 Clock interacting protein circadian DUF296 PF03479.15 PVD32360.1 - 1.5e-27 96.1 0.2 1.7e-27 95.9 0.2 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Pyr_redox_dim PF02852.22 PVD32360.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain zf-UBR PF02207.20 PVD32361.1 - 7.1e-14 51.7 10.9 7.1e-14 51.7 10.9 3.3 2 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 PVD32361.1 - 2.7 8.0 24.5 0.04 13.8 8.3 3.8 3 0 0 3 3 3 0 PHD-finger IPK PF03770.16 PVD32362.1 - 1.1e-41 142.8 0.7 2.6e-41 141.7 0.7 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Salp15 PF12115.8 PVD32362.1 - 0.087 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Gal-bind_lectin PF00337.22 PVD32363.1 - 3.9e-103 340.4 0.0 3.8e-35 120.3 0.0 5.1 4 1 1 5 5 5 5 Galactoside-binding lectin DUF1080 PF06439.11 PVD32363.1 - 0.00058 20.0 0.0 0.48 10.5 0.0 2.4 1 1 0 2 2 2 2 Domain of Unknown Function (DUF1080) WIF PF02019.18 PVD32363.1 - 0.0089 15.7 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 1 WIF domain tRNA_anti-codon PF01336.25 PVD32363.1 - 0.019 14.9 0.0 9 6.4 0.0 3.9 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain OSR1_C PF12202.8 PVD32363.1 - 0.7 10.2 2.9 7.3 6.9 0.0 3.1 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C-terminal domain Metallophos PF00149.28 PVD32364.1 - 8e-30 104.9 0.0 9.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD32364.1 - 8.3e-21 74.2 0.2 1.5e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PI-PLC-X PF00388.19 PVD32365.1 - 3.2e-64 214.9 0.0 8.6e-64 213.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PVD32365.1 - 1.3e-40 138.3 0.1 1.3e-40 138.3 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 PVD32365.1 - 2.3e-25 89.0 0.0 7e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PLC-beta_C PF08703.10 PVD32365.1 - 1.8e-14 54.1 28.1 1.8e-14 54.1 28.1 3.7 4 0 0 4 4 4 1 PLC-beta C terminal EF-hand_like PF09279.11 PVD32365.1 - 4.8e-11 43.0 0.0 4.8e-11 43.0 0.0 2.9 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1154 PF06631.11 PVD32365.1 - 2.1e-08 34.0 1.4 2.1e-08 34.0 1.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) C2 PF00168.30 PVD32365.1 - 8.1e-06 26.1 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain T7SS_ESX_EspC PF10824.8 PVD32365.1 - 0.16 12.5 1.6 8.9 6.9 0.1 3.2 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Herpes_BBRF1 PF04793.12 PVD32365.1 - 0.54 9.2 5.4 0.24 10.4 1.7 2.0 2 0 0 2 2 2 0 BRRF1-like protein Rap_GAP PF02145.15 PVD32368.1 - 3.2e-05 23.6 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 Rap/ran-GAP DUF3602 PF12223.8 PVD32368.1 - 0.11 13.1 0.4 0.36 11.5 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Laminin_G_2 PF02210.24 PVD32369.1 - 6.5e-145 475.9 4.0 1.4e-26 93.5 0.0 6.6 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 PVD32369.1 - 8.1e-102 336.6 0.1 1.3e-21 77.2 0.0 6.5 6 0 0 6 6 6 6 Laminin G domain Laminin_G_3 PF13385.6 PVD32369.1 - 1.4e-14 54.5 0.6 0.0018 18.4 0.0 6.2 6 0 0 6 6 6 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD32369.1 - 4.4e-11 42.9 30.7 0.00011 22.4 4.6 3.8 3 0 0 3 3 3 3 EGF-like domain Syndecan PF01034.20 PVD32369.1 - 3.2e-07 30.2 0.0 6.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain hEGF PF12661.7 PVD32369.1 - 5.7e-06 26.8 25.5 0.0048 17.5 3.0 3.9 3 0 0 3 3 3 3 Human growth factor-like EGF Podoplanin PF05808.11 PVD32369.1 - 0.045 13.9 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Podoplanin LSPR PF06049.12 PVD32370.1 - 3.3 7.9 22.3 2.4e+02 2.3 0.0 10.0 13 0 0 13 13 13 0 Coagulation Factor V LSPD Repeat CABIT PF12736.7 PVD32371.1 - 5.2e-05 22.7 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, G_glu_transpept PF01019.21 PVD32372.1 - 1.9e-122 409.6 0.4 2.6e-90 303.7 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase DUF4043 PF13252.6 PVD32372.1 - 0.059 12.5 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) ANAPC3 PF12895.7 PVD32373.1 - 0.0007 19.8 0.1 0.0059 16.8 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 PVD32373.1 - 0.00071 19.5 6.0 0.23 11.7 0.4 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD32373.1 - 0.0019 18.4 2.0 0.24 11.7 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32373.1 - 0.0022 18.1 0.3 2.6 8.5 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD32373.1 - 0.0089 15.8 0.9 0.91 9.4 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat IBR PF01485.21 PVD32374.1 - 6.6e-19 67.9 43.9 3.4e-13 49.6 8.6 4.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PVD32374.1 - 0.0073 16.6 12.5 0.0073 16.6 12.5 4.3 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 PVD32374.1 - 0.01 15.7 13.0 0.01 15.7 13.0 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 PVD32374.1 - 0.012 15.4 2.0 0.012 15.4 2.0 3.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zinc_ribbon_9 PF14369.6 PVD32374.1 - 0.035 14.4 13.7 1.9 8.8 0.9 4.1 3 0 0 3 3 3 0 zinc-ribbon zf_UBZ PF18439.1 PVD32374.1 - 0.2 11.3 6.5 3.7 7.2 0.1 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PRKCSH-like PF12999.7 PVD32375.1 - 6.7e-24 84.6 13.4 1.2e-23 83.8 12.2 2.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 PVD32375.1 - 6.7e-17 61.6 0.1 1.1e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PVD32375.1 - 5e-05 24.2 0.5 0.00012 23.0 0.5 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 PVD32375.1 - 6 7.2 19.1 7.9 6.8 3.2 3.0 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Asp_Arg_Hydrox PF05118.15 PVD32377.1 - 2.5e-54 183.3 0.2 4.7e-54 182.5 0.2 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 PVD32377.1 - 7.6e-08 31.9 0.7 0.34 11.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD32377.1 - 7.4e-07 29.5 0.0 0.7 10.9 0.1 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD32377.1 - 3.8e-05 24.2 0.0 0.0011 19.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD32377.1 - 5.1e-05 23.5 0.0 3.9 7.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD32377.1 - 0.00013 22.4 0.0 0.21 12.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD32377.1 - 0.00038 20.2 0.9 2.3 8.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD32377.1 - 0.00064 20.2 0.2 0.25 11.9 0.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32377.1 - 0.0027 17.8 0.8 1 9.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SAM_1 PF00536.30 PVD32378.1 - 0.00016 22.0 0.1 0.00045 20.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD32378.1 - 0.014 15.4 0.0 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RPN13_C PF16550.5 PVD32379.1 - 2.3e-33 114.7 1.2 5.4e-33 113.5 1.2 1.6 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 PVD32379.1 - 2.3e-33 114.5 0.2 3.7e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor GerD PF17898.1 PVD32379.1 - 0.032 14.2 2.4 0.26 11.2 0.0 3.0 3 0 0 3 3 3 0 Spore germination GerD central core domain Hydrolase_4 PF12146.8 PVD32380.1 - 1.3e-11 44.3 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD32380.1 - 2e-11 44.1 0.0 7.8e-10 38.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD32380.1 - 4.5e-06 27.4 0.0 9.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyridoxal_deC PF00282.19 PVD32381.1 - 3.8e-20 72.0 0.0 1e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 PVD32381.1 - 8e-13 48.1 0.0 6.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 PVD32381.1 - 0.025 13.7 0.0 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Amidase02_C PF12123.8 PVD32381.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF3593 PF12159.8 PVD32382.1 - 0.18 11.9 1.1 0.34 11.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) PAF-AH_p_II PF03403.13 PVD32383.1 - 1.1e-106 356.5 0.1 7.1e-62 209.1 0.1 2.0 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 PVD32383.1 - 2.7e-06 26.5 0.0 0.0091 14.9 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 PVD32383.1 - 3.9e-06 26.7 0.1 6.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD32383.1 - 0.00012 21.4 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 PVD32383.1 - 0.00074 19.1 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase PF07224.11 PVD32383.1 - 0.00085 18.4 0.0 0.33 9.9 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 PVD32383.1 - 0.0029 18.3 0.0 0.0091 16.6 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PVD32383.1 - 0.0038 16.7 0.0 0.0038 16.7 0.0 2.6 3 1 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PVD32383.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PMP22_Claudin PF00822.20 PVD32385.1 - 5.9e-07 29.5 9.0 8.4e-07 29.0 9.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 PVD32385.1 - 0.031 14.5 9.3 0.068 13.4 8.8 1.8 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF5336 PF17270.2 PVD32385.1 - 0.066 12.8 0.4 0.091 12.4 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Claudin_2 PF13903.6 PVD32385.1 - 5.2 6.8 13.8 1.5e+02 2.0 13.8 2.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EF-hand_5 PF13202.6 PVD32386.1 - 1.3e-21 75.1 0.1 2.9e-06 26.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 PVD32386.1 - 9.9e-20 68.6 0.0 0.0002 20.7 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD32386.1 - 1e-18 65.6 0.1 0.00017 21.3 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD32386.1 - 1.6e-18 66.9 0.1 5.6e-08 33.1 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD32386.1 - 5e-13 48.7 0.1 4.5e-07 29.6 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 PVD32386.1 - 0.041 14.2 0.0 9.5 6.6 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain HTH_Tnp_Tc3_2 PF01498.18 PVD32386.1 - 0.09 13.0 0.0 4.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Transposase SQS_PSY PF00494.19 PVD32387.1 - 1.5e-41 142.7 0.0 2.2e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Octopine_DH PF02317.17 PVD32387.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF3337 PF11816.8 PVD32388.1 - 2.2e-49 167.6 0.0 3.8e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 PVD32388.1 - 6.5e-31 105.9 14.3 1.5e-05 25.7 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32388.1 - 1.8e-07 31.4 2.4 0.26 11.6 0.1 4.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD32388.1 - 0.012 14.3 5.4 2 7.0 0.2 3.8 2 1 2 4 4 4 0 Nucleoporin Nup120/160 RAWUL PF16207.5 PVD32388.1 - 0.013 16.2 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ge1_WD40 PF16529.5 PVD32388.1 - 0.013 14.4 0.7 1.4 7.8 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 PVD32388.1 - 0.021 13.6 1.4 5 5.8 0.1 3.8 2 1 2 4 4 4 0 Nup133 N terminal like WD40_like PF17005.5 PVD32388.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain ULD PF16534.5 PVD32389.1 - 1.3e-35 121.7 0.0 2.4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB CUTL PF16557.5 PVD32389.1 - 1.3e-25 89.4 0.3 3.3e-25 88.0 0.3 1.7 1 0 0 1 1 1 1 CUT1-like DNA-binding domain of SATB HTH_3 PF01381.22 PVD32389.1 - 0.063 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HNF-1_N PF04814.13 PVD32389.1 - 0.5 11.0 0.1 0.5 11.0 0.1 2.2 2 1 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus EMP70 PF02990.16 PVD32390.1 - 1.5e-154 515.5 12.6 2.3e-154 514.9 12.6 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 PTPLA PF04387.14 PVD32391.1 - 1e-39 135.9 4.6 1e-39 135.9 4.6 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF4590 PF15257.6 PVD32392.1 - 1.2e-21 76.8 4.5 4.4e-16 58.8 1.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4590) LRR_6 PF13516.6 PVD32392.1 - 1.5e-12 46.5 15.0 0.00067 19.5 0.1 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 PVD32392.1 - 0.13 12.0 6.5 1.2 8.9 3.6 3.1 2 1 0 2 2 2 0 Leucine rich repeat RRM_1 PF00076.22 PVD32393.1 - 1.1e-16 60.4 0.1 4.3e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD32393.1 - 8e-06 25.5 0.0 9.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PVD32393.1 - 0.04 14.1 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain TPD52 PF04201.15 PVD32394.1 - 3.8e-38 130.6 4.8 5.3e-38 130.2 4.8 1.2 1 0 0 1 1 1 1 Tumour protein D52 family kleA_kleC PF17383.2 PVD32394.1 - 0.0093 16.3 0.3 0.046 14.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized KorC regulated protein A Cep57_CLD_2 PF14197.6 PVD32394.1 - 0.059 13.5 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 PIN_8 PF18476.1 PVD32394.1 - 0.084 12.7 2.2 0.13 12.1 2.2 1.4 1 0 0 1 1 1 0 PIN like domain OmpH PF03938.14 PVD32394.1 - 0.11 12.8 3.5 0.13 12.6 0.9 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 PVD32394.1 - 0.11 12.4 2.9 4.9 7.1 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4763 PF15960.5 PVD32394.1 - 0.16 11.3 1.6 0.25 10.6 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AAA_13 PF13166.6 PVD32394.1 - 0.35 9.5 6.4 1.7 7.2 1.4 2.1 1 1 1 2 2 2 0 AAA domain Ribophorin_II PF05817.14 PVD32395.1 - 7.1e-197 655.8 3.2 3.2e-145 485.2 0.5 2.0 1 1 1 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II KCNQ_channel PF03520.14 PVD32396.1 - 2.4e-37 128.6 4.5 7e-37 127.1 4.5 1.7 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 PVD32396.1 - 5.9e-28 97.7 3.5 8.8e-28 97.2 3.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD32396.1 - 4.4e-14 52.2 2.8 2e-13 50.1 3.1 2.0 1 1 0 1 1 1 1 Ion channel Peptidase_S10 PF00450.22 PVD32400.1 - 2.2e-75 254.6 1.6 1.1e-41 143.7 1.5 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.22 PVD32401.1 - 2.2e-52 178.9 0.1 2.9e-30 106.0 0.0 2.3 1 1 1 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.22 PVD32402.1 - 8.7e-60 203.3 5.6 2.2e-32 113.0 1.1 3.0 1 1 2 3 3 3 3 Serine carboxypeptidase UDPGT PF00201.18 PVD32403.1 - 7.7e-10 38.2 0.1 9.1e-10 37.9 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 PVD32404.1 - 1.7e-42 145.9 0.1 2e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD32404.1 - 3.1e-08 33.8 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 PVD32404.1 - 0.04 13.2 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 LIM PF00412.22 PVD32405.1 - 2.9e-25 88.2 24.6 5.5e-13 48.9 8.3 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 PVD32405.1 - 1.4e-06 27.7 15.7 0.6 9.7 0.1 4.7 4 0 0 4 4 4 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD32405.1 - 0.0026 17.8 26.5 0.94 9.6 0.3 4.2 4 0 0 4 4 4 3 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 PVD32405.1 - 0.012 15.6 2.3 1.7 8.8 0.4 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ACC PF17848.1 PVD32405.1 - 0.027 14.5 3.6 0.28 11.3 0.3 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 PVD32405.1 - 0.036 13.8 29.8 0.49 10.2 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-Mss51 PF13824.6 PVD32405.1 - 0.044 13.9 1.6 0.044 13.9 1.6 3.4 2 2 1 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 PVD32405.1 - 0.21 11.7 26.3 5.5 7.1 8.9 4.3 2 2 0 2 2 2 0 Double zinc ribbon SelR PF01641.18 PVD32405.1 - 0.23 11.5 9.3 1.1 9.4 1.1 2.2 2 0 0 2 2 2 0 SelR domain zf-ribbon_3 PF13248.6 PVD32405.1 - 0.47 9.9 0.1 0.47 9.9 0.1 5.1 6 0 0 6 6 6 0 zinc-ribbon domain MqsA_antitoxin PF15731.5 PVD32405.1 - 1.4 9.0 6.7 12 6.1 0.1 3.0 2 2 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-CCHC_5 PF14787.6 PVD32405.1 - 1.5 8.6 0.1 1.5 8.6 0.1 3.3 3 0 0 3 3 2 0 GAG-polyprotein viral zinc-finger TF_Zn_Ribbon PF08271.12 PVD32405.1 - 1.9 8.0 23.6 0.78 9.3 0.3 4.7 4 1 0 4 4 4 0 TFIIB zinc-binding DUF2616 PF11077.8 PVD32405.1 - 4.5 6.9 10.3 4.5 7.0 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) DUF2688 PF10892.8 PVD32405.1 - 4.9 6.7 10.3 11 5.5 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2688) PSCyt3 PF07627.11 PVD32405.1 - 5.1 7.4 12.7 18 5.7 2.1 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1588) NinD PF17466.2 PVD32405.1 - 6.9 6.8 10.6 14 5.9 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function Thioredoxin PF00085.20 PVD32406.1 - 2.6e-51 171.9 0.0 1.1e-31 108.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Peptidase_S10 PF00450.22 PVD32406.1 - 2.5e-38 132.6 0.7 1.3e-18 67.7 0.0 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase Thioredoxin_6 PF13848.6 PVD32406.1 - 6.9e-08 32.6 0.0 0.0005 20.0 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PVD32406.1 - 6.3e-07 29.8 0.1 0.041 14.3 0.2 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 PVD32406.1 - 0.00023 21.2 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 PVD32406.1 - 0.0055 16.1 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PVD32406.1 - 0.0064 16.8 0.0 0.25 11.7 0.0 3.3 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 PVD32406.1 - 0.065 13.1 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 PVD32406.1 - 0.067 13.4 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like DUF35_N PF12172.8 PVD32407.1 - 0.19 11.6 0.6 0.19 11.6 0.6 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LURAP PF14854.6 PVD32408.1 - 0.0036 17.2 0.4 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Leucine rich adaptor protein FAF PF11250.8 PVD32408.1 - 0.092 13.0 0.0 5.2 7.4 0.0 2.9 2 0 0 2 2 2 0 Fantastic Four meristem regulator Ank_2 PF12796.7 PVD32409.1 - 8e-15 55.2 0.3 2.6e-10 40.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD32409.1 - 8.4e-13 47.3 0.1 5.7e-05 23.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 PVD32409.1 - 2.6e-12 46.6 0.4 2.4e-07 30.9 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PVD32409.1 - 7.2e-11 42.4 0.1 2e-07 31.4 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD32409.1 - 1.8e-10 40.9 0.4 1.6e-06 28.3 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 PVD32410.1 - 3.3e-10 39.4 49.9 8.1e-10 38.1 9.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DHDPS PF00701.22 PVD32411.1 - 2.6e-19 69.0 0.0 1.1e-09 37.4 0.1 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family SF3a60_bindingd PF12108.8 PVD32411.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Ras PF00071.22 PVD32413.1 - 7.8e-41 139.4 0.9 9.6e-41 139.1 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32413.1 - 8.4e-26 90.5 0.4 1.1e-25 90.1 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32413.1 - 1.6e-13 50.5 0.1 2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD32413.1 - 7.3e-09 35.7 0.3 1e-08 35.2 0.3 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD32413.1 - 3e-07 30.0 0.2 3.7e-07 29.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD32413.1 - 1.1e-05 25.0 0.1 1.7e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD32413.1 - 0.00058 19.5 0.3 0.027 14.0 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PVD32413.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 PVD32413.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PVD32413.1 - 0.032 14.1 0.3 0.31 10.9 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 PVD32413.1 - 0.039 13.1 0.1 1 8.4 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 PVD32413.1 - 0.061 13.0 0.2 0.22 11.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 PVD32413.1 - 0.062 13.3 0.3 10 6.2 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.25 PVD32414.1 - 1.2e-17 64.2 0.1 1.6e-10 40.8 0.0 3.0 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PVD32414.1 - 3.9e-06 26.3 0.2 0.00077 18.8 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD32414.1 - 4.6e-06 26.2 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Lac_bphage_repr PF06543.12 PVD32414.1 - 0.03 14.3 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor Ribosomal_L7Ae PF01248.26 PVD32415.1 - 3.4e-26 90.8 0.0 4.1e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 PVD32415.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4421 PF14391.6 PVD32415.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) ANAPC4_WD40 PF12894.7 PVD32416.1 - 1.3e-13 51.0 3.2 3.1e-06 27.4 0.1 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PVD32416.1 - 6.1e-08 32.1 0.6 7.9e-05 21.9 0.0 3.0 3 0 0 3 3 3 2 Coatomer WD associated region TPR_7 PF13176.6 PVD32416.1 - 0.0019 18.1 1.2 0.32 11.1 0.6 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 PVD32416.1 - 0.0053 16.5 0.2 0.29 10.8 0.1 2.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 WD40 PF00400.32 PVD32416.1 - 0.0079 17.0 1.1 77 4.4 0.0 5.3 4 1 1 5 5 5 0 WD domain, G-beta repeat TPR_16 PF13432.6 PVD32416.1 - 0.032 14.9 7.1 3.3 8.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF2A PF08662.11 PVD32416.1 - 0.059 13.2 4.0 0.091 12.6 0.3 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PVD32416.1 - 0.081 12.9 0.6 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DNase_NucA_NucB PF14040.6 PVD32416.1 - 0.086 13.2 0.9 0.17 12.3 0.3 1.8 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB TPR_2 PF07719.17 PVD32416.1 - 0.13 12.4 7.4 2 8.7 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_Tnp_IS1595 PF12760.7 PVD32416.1 - 5.8 7.0 9.6 1.3 9.1 3.7 2.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.20 PVD32417.1 - 1.1e-91 301.6 1.7 3e-31 107.4 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 PVD32417.1 - 8.1e-14 52.0 1.6 0.0006 20.2 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 PVD32417.1 - 1.7e-13 50.6 0.6 1.9e-05 24.2 0.0 3.2 2 1 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PVD32417.1 - 2.8e-11 43.6 0.2 0.054 13.8 0.0 4.4 3 3 1 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.6 PVD32417.1 - 2.8e-10 40.4 2.7 0.014 15.4 0.0 4.9 5 1 1 6 6 6 3 Thioredoxin-like domain AhpC-TSA PF00578.21 PVD32417.1 - 6.3e-07 29.3 0.7 0.8 9.6 0.0 3.3 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_7 PF13899.6 PVD32417.1 - 9.4e-07 28.9 2.2 0.4 10.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 PVD32417.1 - 4.2e-05 23.3 0.3 0.52 10.1 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 PVD32417.1 - 6.1e-05 22.8 5.1 0.4 10.4 0.1 3.3 3 0 0 3 3 3 2 Redoxin TraF PF13728.6 PVD32417.1 - 0.0001 22.2 0.1 0.36 10.6 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein HyaE PF07449.11 PVD32417.1 - 0.00066 19.6 0.0 3.6 7.6 0.0 3.4 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE UCH_1 PF13423.6 PVD32417.1 - 0.0015 18.2 0.4 0.89 9.1 0.1 3.2 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Thioredoxin_4 PF13462.6 PVD32417.1 - 0.0047 17.1 2.7 20 5.3 0.0 4.5 3 2 2 5 5 5 0 Thioredoxin Thioredoxin_5 PF13743.6 PVD32417.1 - 0.023 14.4 2.7 52 3.5 0.0 4.6 3 3 2 5 5 5 0 Thioredoxin Glutaredoxin PF00462.24 PVD32417.1 - 0.052 13.8 4.6 13 6.1 0.1 3.6 3 0 0 3 3 3 0 Glutaredoxin ERp29_N PF07912.13 PVD32417.1 - 0.079 13.1 2.1 0.46 10.6 0.0 3.1 4 1 0 4 4 3 0 ERp29, N-terminal domain Ribosomal_60s PF00428.19 PVD32418.1 - 5.7e-25 87.7 15.1 1.3e-24 86.6 15.1 1.5 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF4149 PF13664.6 PVD32419.1 - 7.4e-20 71.2 7.7 7.4e-20 71.2 7.7 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4149) Amino_oxidase PF01593.24 PVD32420.1 - 3.6e-62 211.1 0.0 9.9e-48 163.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD32420.1 - 3.9e-13 49.4 0.2 1e-12 48.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CW PF07496.15 PVD32420.1 - 8.2e-11 41.8 1.1 1.9e-10 40.6 1.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger SWIRM PF04433.17 PVD32420.1 - 6.3e-09 36.1 0.0 3.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Thi4 PF01946.17 PVD32420.1 - 4e-06 26.3 0.1 7.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PVD32420.1 - 8.1e-06 24.8 0.6 8.2e-05 21.5 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 PVD32420.1 - 1.7e-05 24.8 0.1 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding ubiquitin PF00240.23 PVD32420.1 - 3.2e-05 23.6 0.0 8.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Pyr_redox PF00070.27 PVD32420.1 - 4.1e-05 24.1 0.0 0.00012 22.6 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD32420.1 - 0.00028 20.1 0.2 0.00048 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD32420.1 - 0.0004 19.7 0.3 0.0019 17.5 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PVD32420.1 - 0.00083 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 PVD32420.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 PVD32420.1 - 0.0022 17.3 0.2 0.04 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD32420.1 - 0.006 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PVD32420.1 - 0.012 14.8 0.2 0.024 13.7 0.2 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PVD32420.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 PVD32420.1 - 0.022 14.1 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HGTP_anticodon PF03129.20 PVD32420.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain 2-Hacid_dh_C PF02826.19 PVD32420.1 - 0.035 13.5 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cas1_AcylT PF07779.12 PVD32421.1 - 7.5e-09 35.0 0.0 9e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF4131 PF13567.6 PVD32421.1 - 0.21 11.3 0.8 0.82 9.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Gly_rich_SFCGS PF14272.6 PVD32423.1 - 0.0002 21.4 7.9 2 8.4 1.6 4.8 1 1 5 6 6 6 5 Glycine-rich SFCGS DUF4787 PF16029.5 PVD32423.1 - 0.005 16.9 1.5 0.011 15.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) Met_asp_mut_E PF06368.11 PVD32423.1 - 0.24 9.9 5.1 0.18 10.3 0.6 2.7 1 1 1 2 2 2 0 Methylaspartate mutase E chain (MutE) CsgF PF10614.9 PVD32423.1 - 2.5 8.3 10.3 37 4.6 0.4 3.9 2 1 2 4 4 4 0 Type VIII secretion system (T8SS), CsgF protein CRAL_TRIO PF00650.20 PVD32425.1 - 3.2e-26 91.9 0.1 5e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD32425.1 - 8.7e-08 32.2 0.1 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PVD32425.1 - 9.8e-08 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2002 PF09400.10 PVD32425.1 - 0.043 13.8 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) CUE PF02845.16 PVD32425.1 - 0.072 12.8 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 CUE domain MutS_V PF00488.21 PVD32426.1 - 4.6e-56 189.8 0.0 7.9e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PVD32426.1 - 1.2e-30 107.2 0.0 2.7e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain III PWWP PF00855.17 PVD32426.1 - 1.2e-18 67.3 0.3 5.2e-18 65.2 0.3 2.2 1 0 0 1 1 1 1 PWWP domain MutS_I PF01624.20 PVD32426.1 - 2e-14 53.8 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PVD32426.1 - 6.1e-09 36.3 0.0 3.3e-08 33.9 0.0 2.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 PVD32426.1 - 3.4e-05 24.1 1.0 0.00015 22.1 0.1 2.4 2 0 0 2 2 2 1 MutS family domain IV ANAPC16 PF17256.2 PVD32426.1 - 0.015 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 7tm_1 PF00001.21 PVD32427.1 - 0.00058 19.3 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SARAF PF06682.12 PVD32427.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ZU5 PF00791.20 PVD32428.1 - 7.1e-23 80.8 0.1 2.4e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 ZU5 domain UPA PF17217.3 PVD32428.1 - 9.6e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 UPA domain Death PF00531.22 PVD32428.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 Death domain BK_channel_a PF03493.18 PVD32429.1 - 1.2e-27 95.9 0.2 7.9e-27 93.3 0.0 2.3 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PVD32429.1 - 1.6e-12 47.2 3.2 3.6e-12 46.1 3.2 1.6 1 0 0 1 1 1 1 Ion channel FlaF PF07309.11 PVD32429.1 - 0.06 13.4 0.7 0.14 12.2 0.7 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF TrkA_N PF02254.18 PVD32429.1 - 0.079 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ion_trans PF00520.31 PVD32429.1 - 0.47 9.7 14.7 0.79 8.9 14.7 1.3 1 0 0 1 1 1 0 Ion transport protein 7tm_1 PF00001.21 PVD32430.1 - 5.6e-06 25.9 23.8 6.4e-06 25.7 23.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3169 PF11368.8 PVD32430.1 - 0.0025 17.4 0.3 0.0025 17.4 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) SUa-2TM PF18179.1 PVD32430.1 - 0.023 14.0 0.4 0.023 14.0 0.4 1.9 3 0 0 3 3 3 0 SMODS- and Ubiquitin system-associated 2TM effector domain OATP PF03137.20 PVD32431.1 - 2.1e-142 475.2 19.5 2.5e-142 474.9 19.5 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD32431.1 - 7.8e-14 51.4 22.2 7.8e-14 51.4 22.2 3.1 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD32431.1 - 0.0067 16.5 13.6 0.0067 16.5 13.6 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 PVD32432.1 - 4.6e-09 36.0 0.1 6.5e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EI24 PF07264.11 PVD32432.1 - 0.0032 17.7 2.8 0.05 13.9 2.4 2.0 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF5345 PF17280.2 PVD32432.1 - 4.3 7.4 8.8 0.46 10.5 1.5 2.9 3 1 1 4 4 4 0 Family of unknown function (DUF5345) 7tm_1 PF00001.21 PVD32433.1 - 2.9e-06 26.8 4.5 2.9e-06 26.8 4.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IspA PF04279.15 PVD32433.1 - 0.18 12.0 3.8 0.23 11.6 3.8 1.2 1 0 0 1 1 1 0 Intracellular septation protein A 7tm_1 PF00001.21 PVD32434.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MARVEL PF01284.23 PVD32434.1 - 0.0029 17.6 2.8 0.66 10.0 0.1 2.3 2 0 0 2 2 2 2 Membrane-associating domain 7tm_1 PF00001.21 PVD32435.1 - 4.8e-12 45.8 0.4 6.4e-12 45.4 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRRSV_2b PF07069.11 PVD32435.1 - 0.052 14.1 0.4 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b 7tm_1 PF00001.21 PVD32436.1 - 2.2e-22 79.7 6.0 3e-22 79.2 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EI24 PF07264.11 PVD32436.1 - 0.044 14.0 8.0 0.58 10.4 1.8 2.8 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) CpXC PF14353.6 PVD32436.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 CpXC protein DUF5345 PF17280.2 PVD32436.1 - 0.051 13.5 0.1 0.051 13.5 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5345) MARVEL PF01284.23 PVD32436.1 - 0.077 13.0 15.9 0.96 9.5 6.3 3.3 2 1 1 3 3 3 0 Membrane-associating domain MnhB PF04039.13 PVD32436.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.9 3 1 1 4 4 4 0 Domain related to MnhB subunit of Na+/H+ antiporter 7tm_1 PF00001.21 PVD32438.1 - 4.4e-17 62.3 0.1 5.6e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRRSV_2b PF07069.11 PVD32438.1 - 0.087 13.3 0.8 0.33 11.5 0.1 2.2 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b zf-B_box PF00643.24 PVD32439.1 - 1.4e-08 34.8 10.4 3.6e-07 30.2 2.0 5.3 6 0 0 6 6 6 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD32439.1 - 2.8e-08 33.8 9.4 2.8e-08 33.8 9.4 3.9 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD32439.1 - 1.5e-07 31.2 7.8 1.5e-07 31.2 7.8 4.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD32439.1 - 4.3e-07 29.7 5.9 4.3e-07 29.7 5.9 4.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD32439.1 - 6.7e-07 29.2 10.9 6.7e-07 29.2 10.9 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD32439.1 - 9.2e-07 28.6 10.5 9.2e-07 28.6 10.5 4.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD32439.1 - 6e-06 26.1 6.5 6e-06 26.1 6.5 4.8 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD32439.1 - 2.6e-05 24.5 9.5 2.6e-05 24.5 9.5 4.4 5 0 0 5 5 5 1 Ring finger domain Prok-RING_4 PF14447.6 PVD32439.1 - 0.00027 20.7 8.1 0.00027 20.7 8.1 4.5 5 1 1 6 6 5 1 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 PVD32439.1 - 0.016 15.4 17.3 0.81 9.9 2.9 3.5 2 1 1 3 3 3 0 FYVE-type zinc finger zf-RING_6 PF14835.6 PVD32439.1 - 0.017 14.9 3.7 0.017 14.9 3.7 2.3 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PVD32439.1 - 0.018 14.8 4.3 0.018 14.8 4.3 4.2 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain Reg_prop PF07494.11 PVD32440.1 - 0.0037 17.3 0.0 3.8 8.1 0.0 4.1 4 0 0 4 4 4 1 Two component regulator propeller DUF5074 PF16819.5 PVD32440.1 - 0.03 14.4 0.0 1.3 9.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5074) UDPGT PF00201.18 PVD32441.1 - 0.00024 20.1 0.0 0.00039 19.4 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.6 PVD32441.1 - 0.0085 16.1 0.1 0.015 15.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 PVD32441.1 - 0.075 13.0 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase Family 4 RVT_1 PF00078.27 PVD32442.1 - 1.2e-18 67.4 0.1 2.2e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypsin PF00089.26 PVD32443.1 - 8e-41 140.3 0.1 1.4e-40 139.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin SEA PF01390.20 PVD32443.1 - 1.3e-08 34.9 0.0 0.0028 17.7 0.0 2.6 2 0 0 2 2 2 2 SEA domain Trypsin_2 PF13365.6 PVD32443.1 - 0.0016 19.4 0.0 0.0037 18.2 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain PKD_2 PF16407.5 PVD32443.1 - 0.043 14.0 0.0 1.4 9.1 0.0 2.5 2 1 0 2 2 2 0 PKD-like family Trypsin PF00089.26 PVD32444.1 - 2.9e-12 46.9 0.1 3.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin Pkinase_Tyr PF07714.17 PVD32445.1 - 4.2e-96 321.2 0.0 5.7e-96 320.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD32445.1 - 1.5e-45 155.7 0.0 1.3e-43 149.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 PVD32445.1 - 6.4e-07 29.9 0.5 1.4e-06 28.8 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD32445.1 - 0.00026 21.1 0.0 0.001 19.2 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 PVD32445.1 - 0.00034 20.7 0.1 0.00084 19.5 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD32445.1 - 0.00049 20.1 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD32445.1 - 0.018 15.3 0.1 0.045 14.1 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DM PF00751.18 PVD32446.1 - 7e-17 61.1 24.1 1.7e-08 34.2 6.1 2.4 2 0 0 2 2 2 2 DM DNA binding domain Trypsin PF00089.26 PVD32447.1 - 2.5e-47 161.5 0.3 5.1e-47 160.5 0.3 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD32447.1 - 8.1e-06 26.8 0.1 2.9e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain SEA PF01390.20 PVD32447.1 - 0.0031 17.6 0.1 0.0064 16.6 0.1 1.4 1 0 0 1 1 1 1 SEA domain DUF1986 PF09342.11 PVD32447.1 - 0.038 14.4 0.1 0.13 12.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 PVD32448.1 - 2.1e-80 269.7 1.7 5.8e-51 173.4 0.1 2.5 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 PVD32448.1 - 2.7e-08 34.8 0.0 0.017 16.0 0.0 2.9 2 2 0 2 2 2 2 Trypsin-like peptidase domain SEA PF01390.20 PVD32448.1 - 0.00011 22.3 0.3 0.004 17.2 0.1 2.4 2 0 0 2 2 2 1 SEA domain DUF1986 PF09342.11 PVD32448.1 - 0.012 16.0 0.3 4.3 7.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) DUF316 PF03761.15 PVD32448.1 - 0.038 13.6 0.0 0.66 9.5 0.0 2.9 4 0 0 4 4 4 0 Chymotrypsin family Peptidase-S1 rve PF00665.26 PVD32449.1 - 2.1e-17 63.4 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 PVD32449.1 - 0.044 13.5 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.6 PVD32449.1 - 0.064 13.5 0.0 0.075 13.3 0.0 1.1 1 0 0 1 1 1 0 DDE domain LEDGF PF11467.8 PVD32450.1 - 0.15 11.7 0.1 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Cadherin PF00028.17 PVD32451.1 - 7.3e-09 36.0 0.2 0.00011 22.6 0.0 2.2 2 0 0 2 2 2 2 Cadherin domain Cadherin_4 PF17803.1 PVD32451.1 - 0.0011 19.5 1.7 0.0011 19.5 1.7 2.5 2 1 0 2 2 2 1 Bacterial cadherin-like domain C6 PF01681.17 PVD32451.1 - 0.009 16.5 0.7 0.009 16.5 0.7 1.9 2 1 0 2 2 2 1 C6 domain Neisseria_PilC PF05567.11 PVD32451.1 - 0.068 12.1 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Miff PF05644.11 PVD32453.1 - 2.5e-26 93.0 1.2 4.8e-15 56.0 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff SH3_1 PF00018.28 PVD32454.1 - 1.3e-15 56.7 2.9 3.6e-15 55.3 0.2 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 PVD32454.1 - 4.5e-13 48.8 0.3 4.5e-13 48.8 0.3 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PVD32454.1 - 2.4e-11 43.2 0.0 5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ArfGap PF01412.18 PVD32455.1 - 1.7e-34 118.4 0.1 1.7e-34 118.4 0.1 2.7 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 PVD32455.1 - 3.7e-25 89.0 10.8 7e-25 88.1 10.8 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 PVD32455.1 - 1.7e-18 67.1 1.6 3.7e-18 65.9 0.2 2.4 3 0 0 3 3 3 1 PH domain BAR PF03114.18 PVD32455.1 - 7.2e-09 35.6 5.6 1.5e-08 34.6 5.6 1.5 1 0 0 1 1 1 1 BAR domain PH_9 PF15410.6 PVD32455.1 - 3.6e-06 27.3 1.9 0.0018 18.6 0.1 3.5 2 1 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 PVD32455.1 - 0.0033 17.8 0.1 3.3 8.2 0.0 3.1 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 PVD32455.1 - 0.033 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain FliS PF02561.14 PVD32455.1 - 0.062 13.6 1.0 0.24 11.7 0.1 2.5 2 1 1 3 3 3 0 Flagellar protein FliS PH_17 PF18012.1 PVD32455.1 - 0.1 12.3 0.1 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 PVD32455.1 - 0.1 12.4 2.4 0.31 10.8 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain UBN_AB PF14075.6 PVD32455.1 - 0.63 9.7 9.9 0.3 10.8 5.9 2.4 2 1 0 2 2 2 0 Ubinuclein conserved middle domain zf-C2H2 PF00096.26 PVD32458.1 - 1.6e-59 195.1 131.4 4.1e-05 23.8 0.2 18.9 19 0 0 19 19 18 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD32458.1 - 4.4e-54 176.4 122.3 0.00071 20.2 0.6 19.1 19 0 0 19 19 18 17 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD32458.1 - 2.1e-53 176.4 114.8 5.8e-08 32.8 0.8 19.5 19 0 0 19 19 18 11 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD32458.1 - 5.2e-25 87.1 74.6 0.00048 20.3 0.3 16.8 18 0 0 18 18 17 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD32458.1 - 8.1e-13 48.0 95.0 0.071 13.1 0.3 16.9 16 0 0 16 16 16 7 C2H2-type zinc finger zf-met PF12874.7 PVD32458.1 - 2.4e-11 43.6 73.5 0.0095 16.3 0.5 15.1 15 0 0 15 15 15 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD32458.1 - 1e-07 31.5 90.2 0.068 12.9 0.5 14.8 16 0 0 16 16 16 8 zinc-finger C2H2-type zf-Di19 PF05605.12 PVD32458.1 - 0.0003 21.0 15.1 0.0034 17.6 2.4 10.6 12 1 1 13 13 11 4 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 PVD32458.1 - 0.00084 19.6 13.4 2.1 8.7 0.2 7.3 6 3 2 8 8 7 1 BolA-like protein zf-C2HC_2 PF13913.6 PVD32458.1 - 0.061 13.2 81.9 0.13 12.2 0.2 13.5 15 0 0 15 15 15 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 PVD32458.1 - 0.35 10.7 13.0 5.2 7.0 0.1 5.2 6 0 0 6 6 5 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 PVD32458.1 - 0.41 11.2 29.1 0.89 10.1 0.5 8.6 9 0 0 9 9 8 0 Autophagy receptor zinc finger-C2H2 domain zf-MYST PF17772.1 PVD32458.1 - 3.1 7.5 48.0 0.42 10.2 0.3 11.9 11 3 3 14 14 14 0 MYST family zinc finger domain DUF3291 PF11695.8 PVD32459.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DHHC PF01529.20 PVD32460.1 - 3e-20 72.7 11.6 3e-20 72.7 11.6 2.4 2 0 0 2 2 2 2 DHHC palmitoyltransferase LIDHydrolase PF10230.9 PVD32460.1 - 0.11 12.1 0.7 0.43 10.1 0.1 2.1 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase Myosin_head PF00063.21 PVD32461.1 - 7.2e-58 196.4 0.0 9.6e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MH2 PF03166.14 PVD32461.1 - 3e-19 70.0 0.0 1e-18 68.2 0.0 1.9 2 0 0 2 2 2 1 MH2 domain AAA_19 PF13245.6 PVD32461.1 - 0.0044 17.4 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IQ PF00612.27 PVD32461.1 - 0.017 14.9 0.1 0.05 13.4 0.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_16 PF13191.6 PVD32461.1 - 0.036 14.5 0.1 0.036 14.5 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 PVD32461.1 - 0.075 13.3 2.5 0.12 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 PVD32461.1 - 0.088 12.2 0.9 0.24 10.7 0.9 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PVD32461.1 - 0.16 12.4 0.4 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 RNA helicase DUF4736 PF15883.5 PVD32462.1 - 0.69 9.6 2.8 0.84 9.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Acetyltransf_1 PF00583.25 PVD32463.1 - 1.5e-05 25.2 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 PVD32463.1 - 0.0045 17.7 0.0 0.0075 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD32464.1 - 7.7e-09 35.8 0.0 3.5e-08 33.7 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 PVD32464.1 - 4e-05 24.3 0.0 6.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PVD32464.1 - 0.0028 17.8 0.0 0.0087 16.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD32464.1 - 0.032 14.2 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD32464.1 - 0.053 14.0 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PSS PF03034.15 PVD32465.1 - 8e-106 353.8 22.9 8e-106 353.8 22.9 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase Aldedh PF00171.22 PVD32466.1 - 6.4e-136 453.5 0.0 2.9e-91 306.3 0.0 2.3 1 1 0 2 2 2 2 Aldehyde dehydrogenase family Sulfatase PF00884.23 PVD32466.1 - 3.2e-46 158.1 1.1 5.3e-46 157.4 1.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.8 PVD32466.1 - 6.1e-09 36.5 0.9 6.1e-09 36.5 0.9 2.3 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.22 PVD32466.1 - 0.0014 18.3 0.1 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 PVD32466.1 - 0.024 14.9 0.1 0.51 10.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) ELH PF02323.15 PVD32466.1 - 0.082 12.3 6.7 0.17 11.3 6.7 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor CDC45 PF02724.14 PVD32466.1 - 9.7 4.3 8.3 17 3.6 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ApoO PF09769.9 PVD32467.1 - 1.5e-13 50.8 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O DUF4482 PF14818.6 PVD32469.1 - 0.00016 22.6 34.8 0.0084 17.0 11.7 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4482) TPR_MLP1_2 PF07926.12 PVD32469.1 - 0.0061 16.6 12.8 0.0061 16.6 12.8 3.7 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein SOGA PF11365.8 PVD32470.1 - 1.4e-07 32.5 16.5 1.4e-07 32.5 16.5 15.4 10 6 5 15 15 15 4 Protein SOGA TSC22 PF01166.18 PVD32470.1 - 0.27 11.6 0.0 0.27 11.6 0.0 16.1 13 2 3 16 16 16 0 TSC-22/dip/bun family Ribosomal_S8e PF01201.22 PVD32471.1 - 5.2e-34 117.4 0.0 6.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e TLD PF07534.16 PVD32473.1 - 5.6e-35 120.6 0.2 1.1e-34 119.6 0.2 1.5 1 0 0 1 1 1 1 TLD LysM PF01476.20 PVD32474.1 - 4e-09 36.4 0.0 7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain MRJP PF03022.16 PVD32475.1 - 1.3e-31 110.1 0.0 8.1e-31 107.4 0.0 1.9 1 1 0 1 1 1 1 Major royal jelly protein dCache_2 PF08269.11 PVD32475.1 - 0.13 11.5 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Cache domain Clathrin PF00637.20 PVD32476.1 - 5.2e-15 55.6 13.3 1.7e-11 44.2 4.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_11 PF13414.6 PVD32476.1 - 0.12 12.1 0.1 0.55 10.0 0.1 2.2 1 0 0 1 1 1 0 TPR repeat BBS2_Mid PF14783.6 PVD32476.1 - 0.13 12.3 0.0 4 7.5 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Sec23_helical PF04815.15 PVD32476.1 - 0.53 10.1 2.8 6.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Sec23/Sec24 helical domain zf-ISL3 PF14690.6 PVD32477.1 - 0.077 13.7 0.1 0.23 12.2 0.1 1.9 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Fez1 PF06818.15 PVD32477.1 - 1.4 9.4 55.5 0.22 12.0 21.3 3.2 1 1 2 3 3 3 0 Fez1 AAA_13 PF13166.6 PVD32478.1 - 0.0057 15.4 11.6 0.007 15.1 11.6 1.1 1 0 0 1 1 1 1 AAA domain DUF1729 PF08354.10 PVD32478.1 - 0.023 13.6 1.1 0.034 13.1 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) DUF4407 PF14362.6 PVD32478.1 - 0.11 11.9 13.8 0.16 11.3 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PVD32478.1 - 0.2 11.7 14.0 0.074 13.1 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_6 PF01441.19 PVD32478.1 - 0.24 11.4 7.3 0.75 9.8 7.3 2.0 1 1 0 1 1 1 0 Lipoprotein Golgin_A5 PF09787.9 PVD32478.1 - 0.26 10.7 21.8 0.52 9.7 21.8 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 PVD32478.1 - 0.64 10.5 7.4 5.7 7.4 2.3 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 PVD32478.1 - 0.91 9.6 21.7 5.6 7.0 5.7 3.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 PVD32478.1 - 1 9.5 13.8 6.7 6.9 13.2 2.4 1 1 0 1 1 1 0 TolA binding protein trimerisation Spc7 PF08317.11 PVD32478.1 - 1 8.2 18.9 2.1 7.1 18.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 PVD32478.1 - 1.4 9.4 17.8 1 9.8 2.9 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4618 PF15397.6 PVD32478.1 - 1.4 8.3 18.1 0.54 9.6 14.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF5082 PF16888.5 PVD32478.1 - 1.7 8.9 14.2 3.5 7.9 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) AATF-Che1 PF13339.6 PVD32478.1 - 2.9 8.6 16.3 1.3e+02 3.2 16.3 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4472 PF14739.6 PVD32478.1 - 4 8.2 19.5 0.2 12.4 7.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) PKcGMP_CC PF16808.5 PVD32478.1 - 4.7 7.2 17.6 0.55 10.1 2.0 3.5 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 PVD32478.1 - 6.3 7.0 13.1 3.6 7.8 5.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 PVD32478.1 - 6.7 5.7 20.8 1.9 7.5 5.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 PVD32478.1 - 7.4 5.0 6.3 8.9 4.7 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family T3SSipB PF16535.5 PVD32478.1 - 7.4 7.0 16.5 4.8 7.6 6.1 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB AAA_16 PF13191.6 PVD32480.1 - 6.8e-07 29.8 0.0 3.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 PVD32480.1 - 0.00034 20.5 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD32480.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PVD32480.1 - 0.0055 17.1 0.1 0.017 15.6 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 PVD32480.1 - 0.0059 17.0 0.0 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PVD32480.1 - 0.046 13.7 0.1 0.67 10.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD32480.1 - 0.12 12.6 0.2 0.51 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PVD32480.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.16 PVD32480.1 - 0.16 10.8 0.1 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase ResIII PF04851.15 PVD32480.1 - 0.16 11.9 0.0 0.66 9.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PVD32480.1 - 0.23 11.0 0.7 1.1 8.8 0.2 2.4 2 1 0 2 2 2 0 AAA domain C2 PF00168.30 PVD32481.1 - 1.3e-36 125.0 0.0 1.5e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain PDZ_6 PF17820.1 PVD32481.1 - 1.7e-11 43.7 0.0 4.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 PVD32481.1 - 5.8e-11 42.6 10.1 5.8e-11 42.6 10.1 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger PDZ PF00595.24 PVD32481.1 - 7.2e-08 32.7 0.2 1.8e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 PDZ domain zf-piccolo PF05715.13 PVD32481.1 - 3.2 8.0 8.0 7.9 6.7 8.0 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger MFS_1 PF07690.16 PVD32482.1 - 6.4e-50 170.0 30.9 6.4e-50 170.0 30.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD32482.1 - 2.7e-09 36.4 26.4 1e-07 31.2 25.4 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 PVD32482.1 - 2.2e-05 23.9 21.8 0.00013 21.4 21.8 2.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2530 PF10745.9 PVD32482.1 - 8.9 6.6 11.0 4 7.7 0.4 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2530) zf-H2C2_2 PF13465.6 PVD32484.1 - 2.3e-09 37.3 40.8 4.2e-06 26.9 4.5 6.8 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD32484.1 - 5.7e-08 32.8 48.9 0.00055 20.3 6.2 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD32484.1 - 8.3e-05 23.1 45.8 0.0021 18.7 5.0 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD32484.1 - 0.019 15.2 27.7 0.74 10.2 0.1 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PVD32484.1 - 0.026 14.3 0.5 0.026 14.3 0.5 3.0 3 0 0 3 3 3 0 GAGA factor C1_4 PF07975.12 PVD32484.1 - 0.076 13.3 0.5 0.076 13.3 0.5 4.2 2 2 2 4 4 4 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 PVD32484.1 - 1.2 9.2 34.4 0.12 12.4 0.6 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger LRR_8 PF13855.6 PVD32485.1 - 4.6e-63 208.9 65.7 2.8e-08 33.4 0.2 12.8 5 4 10 15 15 15 14 Leucine rich repeat LRR_4 PF12799.7 PVD32485.1 - 4.5e-51 169.9 71.0 1.9e-05 24.9 0.5 15.9 11 4 3 16 16 16 15 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD32485.1 - 1.5e-11 43.3 58.5 0.51 10.5 0.8 18.3 21 0 0 21 21 21 5 Leucine Rich repeat LRR_1 PF00560.33 PVD32485.1 - 6.5e-10 38.2 59.4 2.9 8.8 0.5 22.1 24 4 0 24 24 24 3 Leucine Rich Repeat LRR_9 PF14580.6 PVD32485.1 - 4.4e-07 29.6 41.3 7.5e-05 22.3 2.2 8.1 2 2 7 10 10 10 4 Leucine-rich repeat CREPT PF16566.5 PVD32485.1 - 0.00029 21.0 3.5 16 5.6 0.0 6.4 6 2 2 8 8 8 1 Cell-cycle alteration and expression-elevated protein in tumour DASH_Dam1 PF08653.10 PVD32485.1 - 0.0064 16.3 3.4 0.39 10.5 0.1 4.3 4 0 0 4 4 4 1 DASH complex subunit Dam1 LRR_5 PF13306.6 PVD32485.1 - 0.4 10.6 3.4 6.7 6.7 0.0 3.4 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) FAA_hydrolase PF01557.18 PVD32486.1 - 9.9e-58 195.4 0.0 1.2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 PVD32486.1 - 3e-10 40.2 0.1 5.7e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Carboxyl_trans PF01039.22 PVD32487.1 - 6.4e-140 467.1 0.1 2e-139 465.5 0.1 1.6 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PVD32487.1 - 0.00079 19.0 0.2 0.94 8.9 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Ku PF02735.16 PVD32488.1 - 4.8e-44 150.5 0.0 7.3e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 PVD32488.1 - 5.5e-37 126.6 1.4 1.3e-36 125.3 1.4 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 PVD32488.1 - 1.4e-25 90.3 2.6 1.5e-24 87.0 0.0 2.3 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain CUB PF00431.20 PVD32488.1 - 1.3e-18 67.3 0.0 2.4e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 CUB domain Ku_C PF03730.14 PVD32488.1 - 6.3e-11 42.8 3.1 1.7e-09 38.2 0.0 3.4 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 PVD32488.1 - 0.0001 22.6 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Fer4_8 PF13183.6 PVD32488.1 - 0.021 15.2 1.8 0.083 13.3 1.8 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF4795 PF16043.5 PVD32488.1 - 0.1 12.2 0.5 0.21 11.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Peptidase_C98 PF15499.6 PVD32489.1 - 7.3e-80 268.3 1.9 7.3e-80 268.3 1.9 2.1 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase RFX5_DNA_bdg PF14621.6 PVD32489.1 - 0.058 13.2 24.2 0.35 10.6 0.3 6.3 6 0 0 6 6 6 0 RFX5 DNA-binding domain DUF5549 PF17703.1 PVD32489.1 - 0.063 12.9 9.2 0.031 13.9 3.9 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5549) RITA PF17066.5 PVD32490.1 - 5.6e-14 52.4 7.9 7.1e-14 52.0 7.9 1.1 1 0 0 1 1 1 1 RBPJ-interacting and tubulin associated protein Ion_trans PF00520.31 PVD32491.1 - 2.9e-40 138.0 12.7 3.9e-40 137.6 12.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD32491.1 - 4.3e-29 100.7 0.1 1.5e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD32491.1 - 8.4e-12 44.9 4.6 8.4e-12 44.9 4.6 2.6 2 1 0 2 2 2 1 Ion channel PKD_channel PF08016.12 PVD32491.1 - 0.19 10.4 7.1 0.015 14.0 2.4 1.4 2 0 0 2 2 2 0 Polycystin cation channel DUF3185 PF11381.8 PVD32491.1 - 0.26 11.3 1.2 0.58 10.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Ion_trans PF00520.31 PVD32493.1 - 5.7e-30 104.3 4.1 7.5e-30 103.9 4.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD32493.1 - 4.9e-11 42.4 9.4 1.6e-10 40.8 9.4 1.8 1 1 0 1 1 1 1 Ion channel MARVEL PF01284.23 PVD32493.1 - 0.018 15.1 2.1 0.018 15.1 2.1 1.7 2 1 0 2 2 2 0 Membrane-associating domain Vma12 PF11712.8 PVD32493.1 - 0.22 11.6 0.9 0.6 10.2 0.4 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BTB_2 PF02214.22 PVD32494.1 - 7e-30 103.2 0.0 2.6e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.31 PVD32494.1 - 4.7e-10 39.1 2.0 6.4e-10 38.7 2.0 1.2 1 0 0 1 1 1 1 Ion transport protein CUB PF00431.20 PVD32495.1 - 1.8e-82 272.9 3.8 2.7e-20 72.7 0.2 7.1 7 0 0 7 7 7 6 CUB domain UL11 PF11094.8 PVD32495.1 - 0.028 14.3 0.5 4.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Membrane-associated tegument protein FGFR3_TM PF18123.1 PVD32495.1 - 2 8.0 6.1 4.3 7.0 6.1 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Cpn60_TCP1 PF00118.24 PVD32496.1 - 7.6e-153 509.7 12.1 8.6e-153 509.5 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 PVD32496.1 - 0.045 13.0 0.1 0.089 12.0 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ECH_1 PF00378.20 PVD32497.1 - 2.9e-38 131.6 0.1 3.7e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PVD32497.1 - 3.4e-18 66.2 0.1 4.7e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PVD32497.1 - 0.014 15.4 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 OATP PF03137.20 PVD32498.1 - 8.3e-130 433.6 21.1 6.4e-118 394.4 11.2 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD32498.1 - 2.5e-23 82.6 21.6 2.8e-23 82.4 16.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3899 PF13038.6 PVD32498.1 - 0.61 10.6 4.7 7.9 7.1 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) OATP PF03137.20 PVD32499.1 - 9.1e-176 585.3 19.1 1.1e-175 585.0 19.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD32499.1 - 1.5e-26 93.1 29.3 1.3e-25 90.1 20.0 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD32499.1 - 9.1e-08 32.1 7.3 2.3e-07 30.8 7.3 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD32499.1 - 0.0066 16.4 6.8 0.017 15.1 6.8 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Neurensin PF14927.6 PVD32499.1 - 0.022 14.5 4.1 1.1 9.0 0.2 3.5 3 0 0 3 3 3 0 Neurensin Flavi_NS4A PF01350.17 PVD32499.1 - 0.68 9.9 4.2 1.7 8.6 0.1 3.2 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A F-box-like PF12937.7 PVD32500.1 - 4.7e-10 39.2 0.8 4.7e-10 39.2 0.8 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD32500.1 - 0.00014 21.6 0.9 0.00034 20.4 0.9 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 PVD32500.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 PVD32500.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat V-ATPase_G PF03179.15 PVD32500.1 - 0.12 12.9 2.4 0.26 11.9 2.4 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit A_deaminase PF00962.22 PVD32501.1 - 1.8e-43 149.1 0.0 9.6e-32 110.6 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase TFIIS_M PF07500.14 PVD32503.1 - 6.6e-33 113.5 2.2 6.6e-33 113.5 2.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain VPS13_C PF16909.5 PVD32503.1 - 6e-30 104.3 0.7 2.7e-29 102.2 0.1 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SPOC PF07744.13 PVD32503.1 - 4.6e-28 98.0 0.0 1.2e-27 96.7 0.0 1.8 1 0 0 1 1 1 1 SPOC domain Chorein_N PF12624.7 PVD32503.1 - 4e-25 88.2 0.0 1.8e-24 86.1 0.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 BRK PF07533.16 PVD32503.1 - 8.1e-14 51.0 0.0 2.3e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 BRK domain VPS13 PF16908.5 PVD32503.1 - 0.00026 20.9 0.2 0.00026 20.9 0.2 2.9 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 PVD32503.1 - 0.00035 20.9 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain SHR-BD PF06650.12 PVD32503.1 - 0.074 12.4 0.0 4.8 6.5 0.1 3.4 3 1 0 4 4 4 0 SHR-binding domain of vacuolar-sorting associated protein 13 DUF445 PF04286.12 PVD32504.1 - 0.0018 18.1 0.2 0.0057 16.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF2018 PF09442.10 PVD32504.1 - 0.23 12.4 4.6 36 5.4 0.1 5.1 4 2 0 5 5 5 0 Domain of unknown function (DUF2018) LAS2 PF15792.5 PVD32504.1 - 0.83 10.2 4.6 1.1e+02 3.5 0.1 4.8 2 1 2 4 4 4 0 Lung adenoma susceptibility protein 2 ShK PF01549.24 PVD32504.1 - 3.4 8.3 40.0 0.61 10.7 6.9 4.9 4 0 0 4 4 4 0 ShK domain-like E2F_CC-MB PF16421.5 PVD32506.1 - 9.5e-24 83.6 0.0 1.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 PVD32507.1 - 6.1e-25 87.1 0.1 1.3e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Rad17 PF03215.15 PVD32507.1 - 0.094 12.6 0.2 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain TrmB PF01978.19 PVD32507.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_23 PF13489.6 PVD32508.1 - 0.071 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L10 PF00466.20 PVD32509.1 - 4.6e-22 78.1 0.1 2.7e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 PVD32509.1 - 3.9e-21 75.4 6.3 3.9e-21 75.4 6.3 1.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 PVD32509.1 - 8.2e-20 70.6 0.5 1.6e-19 69.7 0.5 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Phosducin PF02114.16 PVD32510.1 - 0.00085 18.3 0.6 0.002 17.2 0.1 1.7 1 1 1 2 2 2 1 Phosducin S6OS1 PF15676.5 PVD32510.1 - 0.02 13.4 1.2 0.02 13.4 1.2 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family V-SNARE PF05008.15 PVD32511.1 - 0.00075 19.8 0.3 0.0015 18.9 0.3 1.5 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Syntaxin_2 PF14523.6 PVD32511.1 - 0.0044 17.4 0.5 0.31 11.4 0.2 2.0 1 1 1 2 2 2 2 Syntaxin-like protein Focal_AT PF03623.13 PVD32511.1 - 0.033 14.2 2.1 0.088 12.8 2.1 1.5 1 1 0 1 1 1 0 Focal adhesion targeting region DAGK_acc PF00609.19 PVD32512.1 - 7.1e-54 182.5 0.0 1.4e-53 181.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.23 PVD32512.1 - 2.6e-31 108.1 0.1 3e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DAGK_cat PF00781.24 PVD32512.1 - 1.2e-22 79.9 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PVD32512.1 - 3e-15 55.8 31.9 2.7e-10 40.0 11.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TUG-UBL1 PF11470.8 PVD32512.1 - 0.0002 21.5 0.0 0.43 10.8 0.0 3.1 3 0 0 3 3 3 2 TUG ubiquitin-like domain Ras_bdg_2 PF14847.6 PVD32512.1 - 0.02 15.2 0.0 0.19 12.1 0.0 2.5 2 1 0 2 2 2 0 Ras-binding domain of Byr2 Ufm1 PF03671.14 PVD32512.1 - 0.11 12.5 0.1 4.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin fold modifier 1 protein zf-H2C2_5 PF13909.6 PVD32513.1 - 1.6e-10 40.5 129.8 0.0069 16.1 4.1 19.5 20 0 0 20 20 20 14 C2H2-type zinc-finger domain zf-RanBP PF00641.18 PVD32513.1 - 0.028 13.7 0.0 0.028 13.7 0.0 6.2 9 0 0 9 9 9 0 Zn-finger in Ran binding protein and others zf-H2C2_2 PF13465.6 PVD32513.1 - 0.059 13.8 0.2 0.059 13.8 0.2 20.8 25 0 0 25 25 25 0 Zinc-finger double domain Whib PF02467.16 PVD32513.1 - 0.12 13.0 4.8 21 5.8 0.2 4.7 3 0 0 3 3 3 0 Transcription factor WhiB zf-C2HE PF16278.5 PVD32513.1 - 0.16 12.4 0.0 0.16 12.4 0.0 12.2 14 3 1 15 15 15 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 PVD32514.1 - 1.9 9.1 19.1 3.2 8.3 1.3 4.9 5 0 0 5 5 5 0 Zinc-finger double domain OrsD PF12013.8 PVD32514.1 - 3.5 8.1 9.3 11 6.5 0.0 4.4 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D GILT PF03227.16 PVD32517.1 - 0.031 14.5 0.3 0.052 13.8 0.3 1.4 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) PMP22_Claudin PF00822.20 PVD32518.1 - 1.3e-06 28.4 5.8 1.9e-06 27.9 5.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 PVD32518.1 - 0.003 17.1 9.0 0.0051 16.3 9.0 1.3 1 0 0 1 1 1 1 Clc-like Claudin_3 PF06653.11 PVD32518.1 - 0.016 15.2 9.5 0.029 14.3 9.5 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like 7tm_3 PF00003.22 PVD32518.1 - 0.016 14.9 5.4 0.02 14.6 5.4 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR SCAMP PF04144.13 PVD32518.1 - 0.025 14.9 8.6 0.028 14.7 8.6 1.1 1 0 0 1 1 1 0 SCAMP family Claudin_2 PF13903.6 PVD32518.1 - 0.067 12.9 8.4 0.093 12.5 8.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Luteo_Vpg PF01659.16 PVD32518.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein HisKA_4TM PF16926.5 PVD32518.1 - 0.21 11.1 5.6 0.45 10.1 0.4 2.4 2 1 1 3 3 3 0 Archaeal 4TM region of histidine kinase DUF2254 PF10011.9 PVD32518.1 - 1.8 7.3 6.6 6.1 5.6 1.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) MitoNEET_N PF10660.9 PVD32518.1 - 6 7.0 6.1 13 5.9 0.1 2.8 1 1 2 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3917 PF13055.6 PVD32519.1 - 0.15 12.5 2.4 0.34 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) 5-FTHF_cyc-lig PF01812.20 PVD32520.1 - 3.5e-24 85.7 0.0 7.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0020 PF01170.18 PVD32521.1 - 1.2e-10 41.4 0.0 4.6e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 PVD32521.1 - 9.4e-07 28.8 0.0 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 PVD32521.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 PVD32521.1 - 0.0045 17.6 0.0 0.016 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain THUMP PF02926.17 PVD32521.1 - 0.0076 16.3 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 PVD32521.1 - 0.017 15.8 0.0 0.073 13.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PVD32521.1 - 0.035 13.7 0.0 0.14 11.8 0.0 1.9 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Cons_hypoth95 PF03602.15 PVD32521.1 - 0.037 13.7 0.1 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PVD32521.1 - 0.092 13.5 0.0 5.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.15 PVD32521.1 - 0.15 11.7 0.1 2.5 7.7 0.0 2.3 1 1 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 PVD32521.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.22 PVD32522.1 - 2e-50 170.6 0.0 2.3e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32522.1 - 2.8e-31 108.2 0.1 5e-31 107.4 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32522.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD32522.1 - 7.4e-06 25.6 0.3 0.0012 18.4 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD32522.1 - 2.6e-05 24.3 0.1 5.2e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD32522.1 - 0.00038 20.0 0.0 0.0018 17.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 PVD32522.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 PVD32522.1 - 0.0043 17.0 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 PVD32522.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PVD32522.1 - 0.025 14.3 0.1 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 PVD32522.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PVD32522.1 - 0.028 14.7 0.0 0.11 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 PVD32522.1 - 0.13 11.4 0.0 9.8 5.2 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit TUDOR PF00567.24 PVD32526.1 - 8.4e-34 116.2 5.5 3.2e-14 53.0 0.0 4.4 3 1 1 4 4 4 4 Tudor domain OST-HTH PF12872.7 PVD32526.1 - 2.9e-16 59.0 0.0 3.2e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 OST-HTH/LOTUS domain SNF PF00209.18 PVD32527.1 - 5.9e-49 167.1 43.7 2.7e-27 95.6 22.3 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Bystin PF05291.11 PVD32528.1 - 3.6e-112 374.4 4.5 6e-112 373.7 4.5 1.3 1 0 0 1 1 1 1 Bystin EGF_2 PF07974.13 PVD32529.1 - 3.1 8.3 10.3 7.7 7.0 10.3 1.7 1 0 0 1 1 1 0 EGF-like domain DCX PF03607.17 PVD32530.1 - 6.3e-18 64.6 0.0 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Doublecortin DCX PF03607.17 PVD32531.1 - 1.5e-14 53.8 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Doublecortin IQ PF00612.27 PVD32532.1 - 1.4e-19 68.0 7.8 2.3e-05 23.8 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif DCX PF03607.17 PVD32532.1 - 5.6e-07 29.6 0.1 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Doublecortin Sulfotransfer_3 PF13469.6 PVD32533.1 - 8.1e-12 46.0 4.1 1.2e-10 42.2 4.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32533.1 - 1.2e-11 44.6 1.4 1.8e-11 44.0 1.4 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Rad52_Rad22 PF04098.15 PVD32535.1 - 1.3e-06 28.5 0.1 1.9e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein NEAT PF05031.12 PVD32535.1 - 0.067 13.8 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 Iron Transport-associated domain 2-oxoacid_dh PF00198.23 PVD32536.1 - 1.8e-82 276.3 0.0 2.4e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PVD32536.1 - 9.5e-19 67.0 1.7 2.2e-18 65.8 0.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 PVD32536.1 - 5.5e-12 45.8 0.0 1.4e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PVD32536.1 - 0.00016 21.5 0.0 0.00055 19.7 0.0 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like Dehydrin PF00257.19 PVD32537.1 - 5.3 7.6 13.1 28 5.2 10.9 2.3 1 1 1 2 2 2 0 Dehydrin HRM PF02793.22 PVD32538.1 - 6.3e-13 48.8 2.5 1.1e-12 48.0 2.5 1.4 1 0 0 1 1 1 1 Hormone receptor domain Pox_P21 PF05313.12 PVD32538.1 - 0.77 9.3 9.2 1 8.9 3.1 2.4 2 0 0 2 2 2 0 Poxvirus P21 membrane protein 7tm_1 PF00001.21 PVD32539.1 - 4.1e-19 68.9 9.3 6.9e-19 68.2 9.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD32539.1 - 1.3e-07 31.6 9.2 2.5e-07 30.6 9.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx MutL_C PF08676.11 PVD32540.1 - 0.023 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 MutL C terminal dimerisation domain HEAT_EZ PF13513.6 PVD32541.1 - 0.0023 18.4 1.4 38 4.9 0.1 5.2 5 2 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 PVD32541.1 - 0.0097 16.3 0.1 2 8.8 0.0 3.8 4 1 0 4 4 4 1 HEAT repeats MAGE_N PF12440.8 PVD32542.1 - 0.39 11.4 2.5 0.62 10.8 2.5 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Tetraspanin PF00335.20 PVD32543.1 - 3.7e-25 89.0 4.0 9.6e-25 87.6 4.0 1.6 1 0 0 1 1 1 1 Tetraspanin family Guanylate_cyc PF00211.20 PVD32544.1 - 8e-62 208.1 0.0 1.1e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 PVD32546.1 - 7.2e-07 28.7 9.9 9.7e-07 28.3 9.9 1.1 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region CcmH PF03918.14 PVD32546.1 - 0.024 14.0 0.1 0.024 14.0 0.1 1.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein FixQ PF05545.11 PVD32546.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.6 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ DUF2070 PF09843.9 PVD32546.1 - 1.1 7.4 13.6 1.5 7.1 13.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Myco_arth_vir_N PF09610.10 PVD32546.1 - 2.8 8.1 6.1 0.43 10.7 0.4 2.5 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DLH PF01738.18 PVD32547.1 - 2.4e-52 177.7 0.0 2.6e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 PVD32547.1 - 1e-06 28.2 0.0 0.0044 16.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 PVD32547.1 - 1e-06 28.8 1.0 0.034 14.1 0.1 2.5 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 PVD32547.1 - 0.0004 19.9 0.2 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 PVD32547.1 - 0.001 17.8 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 PVD32547.1 - 0.001 19.7 0.5 0.087 13.4 0.4 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PVD32547.1 - 0.0013 18.6 0.1 0.0037 17.1 0.1 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 PVD32547.1 - 0.0086 15.7 0.3 0.014 15.0 0.3 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 PVD32547.1 - 0.021 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2990 PF11693.8 PVD32547.1 - 0.025 14.7 1.1 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Abhydrolase_1 PF00561.20 PVD32547.1 - 0.031 13.9 0.3 0.51 9.9 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF3395 PF11875.8 PVD32547.1 - 0.059 13.3 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DLH PF01738.18 PVD32548.1 - 1.4e-52 178.4 6.4 6.4e-44 150.1 0.2 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 PVD32548.1 - 0.0056 15.4 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 PVD32548.1 - 0.0061 16.2 0.0 0.02 14.6 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD32548.1 - 0.026 13.8 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 PVD32548.1 - 0.036 14.0 1.5 0.41 10.5 0.1 2.6 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 PVD32548.1 - 0.047 14.3 0.0 0.09 13.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 PVD32548.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 EF-hand_7 PF13499.6 PVD32549.1 - 4.5e-12 46.2 2.3 1.5e-05 25.3 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD32549.1 - 9.4e-09 34.2 2.5 9e-05 21.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD32549.1 - 3.9e-06 26.4 1.0 0.077 13.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD32549.1 - 1.2e-05 25.1 2.8 0.028 14.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD32549.1 - 0.00094 18.6 2.0 0.032 13.7 0.1 2.7 2 1 0 2 2 2 1 EF hand RST PF12174.8 PVD32549.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 PVD32549.1 - 0.11 13.3 0.3 6.7 7.6 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain CAP-ZIP_m PF15255.6 PVD32551.1 - 3.1e-16 59.9 10.9 9.1e-14 51.9 3.0 4.3 1 1 1 2 2 2 2 WASH complex subunit CAP-Z interacting, central region Nucleoporin_FG PF13634.6 PVD32551.1 - 9.9e-05 23.1 35.1 0.033 15.0 0.4 8.7 7 3 0 8 8 8 3 Nucleoporin FG repeat region Keratin PF02422.16 PVD32551.1 - 0.047 13.4 0.5 0.16 11.7 0.5 1.9 1 0 0 1 1 1 0 Keratin zf-C2H2_4 PF13894.6 PVD32552.1 - 1.1e-15 56.9 52.8 0.0022 18.7 1.9 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD32552.1 - 4.8e-13 48.8 61.7 0.0008 19.7 4.4 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD32552.1 - 5e-10 39.3 52.3 0.00037 20.8 0.4 7.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-met PF12874.7 PVD32552.1 - 1.7e-06 28.2 35.5 0.05 14.0 0.3 6.9 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD32552.1 - 0.014 15.4 34.8 0.057 13.4 0.7 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger Cript PF10235.9 PVD32552.1 - 0.065 13.8 1.0 0.065 13.8 1.0 3.8 3 2 0 3 3 3 0 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 PVD32552.1 - 0.17 12.7 17.8 0.6 10.9 0.7 3.9 3 1 1 4 4 4 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 PVD32552.1 - 0.21 11.9 0.3 0.21 11.9 0.3 7.0 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 PVD32552.1 - 0.21 11.2 12.5 0.79 9.4 0.1 3.2 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain U71 PF17474.2 PVD32552.1 - 0.25 11.3 2.9 1.9 8.5 0.0 3.4 3 0 0 3 3 3 0 Tegument protein UL11 homolog Zn-ribbon_8 PF09723.10 PVD32552.1 - 0.32 11.2 19.2 8.5 6.6 0.3 4.8 3 1 2 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD32552.1 - 0.44 10.9 33.5 1.5 9.2 2.9 5.4 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF2321 PF10083.9 PVD32552.1 - 0.45 10.1 11.6 1.9 8.1 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-Dof PF02701.15 PVD32552.1 - 0.74 10.0 8.1 0.26 11.5 3.0 2.8 2 0 0 2 2 2 0 Dof domain, zinc finger Rpr2 PF04032.16 PVD32552.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.5 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2256 PF10013.9 PVD32552.1 - 2.6 8.2 0.0 2.6 8.2 0.0 5.0 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) WD40 PF00400.32 PVD32553.1 - 4.9e-36 122.1 20.6 5.3e-10 39.7 0.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 PVD32553.1 - 5.8e-27 94.5 0.4 2.1e-26 92.6 1.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 PVD32553.1 - 1.1e-10 41.6 0.0 0.00039 20.7 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3080 PF11279.8 PVD32553.1 - 0.065 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Tetraspanin PF00335.20 PVD32554.1 - 4.5e-40 137.8 2.8 5.5e-40 137.5 2.8 1.0 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 PVD32554.1 - 0.21 11.2 2.3 0.24 11.0 0.2 1.9 2 0 0 2 2 2 0 SUR7/PalI family Phage_holin_3_6 PF07332.11 PVD32554.1 - 6.6 6.8 12.2 0.23 11.5 3.9 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 PVD32555.1 - 1.9e-23 83.4 1.2 5.5e-23 81.9 0.3 1.8 2 0 0 2 2 2 1 Tetraspanin family Tetraspanin PF00335.20 PVD32556.1 - 1.3e-44 152.6 3.6 1.5e-44 152.4 3.6 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 PVD32556.1 - 0.04 13.5 7.1 0.089 12.4 0.8 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF2207 PF09972.9 PVD32556.1 - 2 7.1 3.5 0.73 8.5 1.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) tRNA_int_endo PF01974.17 PVD32557.1 - 1.3e-13 50.8 0.0 3.1e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 PVD32557.1 - 4.3e-06 26.3 0.1 0.0011 18.5 0.0 2.9 3 0 0 3 3 3 2 tRNA intron endonuclease, N-terminal domain COesterase PF00135.28 PVD32558.1 - 5.9e-111 371.9 0.0 8.7e-75 252.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD32558.1 - 3.2e-06 27.2 0.2 1.5e-05 25.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TMEM132D_C PF15706.5 PVD32558.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PAF-AH_p_II PF03403.13 PVD32558.1 - 0.057 11.9 0.6 3.7 6.0 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Cadherin_C_2 PF16492.5 PVD32558.1 - 0.19 12.5 0.7 2.6 8.8 1.6 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Chlorophyllase2 PF12740.7 PVD32558.1 - 0.31 9.9 0.8 2.1 7.2 0.8 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme PMP22_Claudin PF00822.20 PVD32559.1 - 3.3e-07 30.3 4.9 4.1e-07 30.0 4.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD32559.1 - 9.1e-07 29.0 3.9 1.2e-06 28.5 3.9 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 PVD32559.1 - 2.9e-06 27.2 14.3 3.6e-06 26.9 14.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PIRT PF15099.6 PVD32559.1 - 7.9e-05 22.2 0.1 9.3e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Syndecan PF01034.20 PVD32559.1 - 0.014 15.3 0.8 0.024 14.5 0.0 1.8 2 0 0 2 2 2 0 Syndecan domain YtpI PF14007.6 PVD32559.1 - 0.076 13.2 4.6 0.18 12.0 4.6 1.5 1 1 0 1 1 1 0 YtpI-like protein DuoxA PF10204.9 PVD32559.1 - 0.085 11.9 6.5 0.13 11.2 6.4 1.3 1 1 0 1 1 1 0 Dual oxidase maturation factor SUR7 PF06687.12 PVD32559.1 - 0.17 11.5 8.9 0.21 11.2 8.9 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3382 PF11862.8 PVD32559.1 - 1.9 8.8 9.1 0.59 10.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Ras PF00071.22 PVD32560.1 - 1e-35 122.8 0.0 1.8e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32560.1 - 3e-20 72.6 0.0 8.2e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Bromodomain PF00439.25 PVD32560.1 - 1.2e-14 54.1 0.4 5.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Bromodomain DnaJ PF00226.31 PVD32560.1 - 4e-11 42.9 0.0 9.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.21 PVD32560.1 - 1.8e-09 37.3 0.0 9.8e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family PWWP PF00855.17 PVD32560.1 - 1.6e-06 28.4 0.1 1.6e-06 28.4 0.1 3.2 3 0 0 3 3 3 1 PWWP domain zf-MYND PF01753.18 PVD32560.1 - 0.00046 20.2 15.5 0.00046 20.2 15.5 3.5 3 1 0 3 3 3 1 MYND finger GTP_EFTU PF00009.27 PVD32560.1 - 0.001 18.6 0.0 0.0035 16.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TRAM_LAG1_CLN8 PF03798.16 PVD32561.1 - 8.3e-20 71.4 10.6 8.3e-20 71.4 10.6 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 PVD32561.1 - 1.2e-19 69.7 0.2 1.2e-19 69.7 0.2 1.9 2 0 0 2 2 2 1 TRAM1-like protein Exostosin PF03016.15 PVD32562.1 - 5e-28 98.2 0.0 8.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 PVD32563.1 - 1.5e-91 306.1 0.0 3.2e-91 305.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Tubulin PF00091.25 PVD32564.1 - 2.3e-45 155.2 0.0 5.2e-45 154.1 0.0 1.6 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD32564.1 - 7.7e-29 100.4 0.0 1.2e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain MRP-S28 PF10213.9 PVD32564.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein CRAL_TRIO PF00650.20 PVD32565.1 - 2.8e-28 98.6 0.0 5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD32565.1 - 2.6e-08 33.9 0.7 6.6e-08 32.6 0.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PVD32565.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Amino_oxidase PF01593.24 PVD32566.1 - 4.3e-127 425.1 0.0 2.3e-126 422.8 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 PVD32566.1 - 2.5e-19 69.4 0.2 1.9e-18 66.6 0.0 2.5 3 0 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.6 PVD32566.1 - 2.1e-12 47.1 1.0 4.9e-12 45.9 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD32566.1 - 1.8e-08 34.4 0.4 1.2e-07 31.6 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PVD32566.1 - 6e-06 25.7 0.1 1.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 PVD32566.1 - 4e-05 23.0 0.3 0.00012 21.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PVD32566.1 - 0.00016 21.1 0.6 0.0062 15.8 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD32566.1 - 0.00048 19.3 1.3 0.001 18.3 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PVD32566.1 - 0.00095 18.0 0.8 0.0029 16.4 0.8 1.8 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PVD32566.1 - 0.0012 19.3 5.8 0.011 16.2 0.6 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PVD32566.1 - 0.0028 16.9 0.3 0.0056 15.9 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 PVD32566.1 - 0.0051 16.1 2.8 0.0063 15.8 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 PVD32566.1 - 0.0075 15.7 3.0 0.0075 15.7 3.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PVD32566.1 - 0.059 12.4 0.3 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FUSC PF04632.12 PVD32566.1 - 0.16 10.5 1.9 0.23 9.9 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF489 PF04356.12 PVD32566.1 - 0.25 11.3 2.2 0.59 10.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) GIDA PF01134.22 PVD32566.1 - 0.33 10.0 7.4 0.091 11.8 3.7 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A Herpes_UL33 PF03581.13 PVD32566.1 - 0.37 11.2 1.6 2.2 8.7 0.8 2.4 2 0 0 2 2 2 0 Herpesvirus UL33-like protein 3HCDH_N PF02737.18 PVD32566.1 - 1.8 8.4 4.6 0.56 10.1 0.5 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SlyX PF04102.12 PVD32566.1 - 2.4 8.9 9.2 26 5.5 4.7 2.9 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.10 PVD32566.1 - 5 7.3 14.3 2.4 8.4 9.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Vps51 PF08700.11 PVD32566.1 - 5.1 7.3 7.6 3.8 7.7 3.0 2.6 2 1 0 2 2 2 0 Vps51/Vps67 E3_UFM1_ligase PF09743.9 PVD32567.1 - 1.8e-102 342.6 2.1 3.8e-102 341.5 2.1 1.6 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Csm1_B PF18211.1 PVD32567.1 - 0.24 11.3 1.9 0.66 9.9 0.4 2.6 2 1 0 2 2 2 0 Csm1 subunit domain B PCI PF01399.27 PVD32567.1 - 1 9.9 5.8 62 4.2 0.0 4.6 5 1 0 5 5 5 0 PCI domain HpaP PF09483.10 PVD32567.1 - 1.9 8.8 5.0 1.7 8.9 0.4 3.0 3 0 0 3 3 3 0 Type III secretion protein (HpaP) PX PF00787.24 PVD32568.1 - 7.5e-06 25.9 2.7 8e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 PX domain UCR_14kD PF02271.16 PVD32569.1 - 1.5e-33 114.7 0.9 1.8e-33 114.4 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit p450 PF00067.22 PVD32570.1 - 9.2e-87 291.7 0.0 1.6e-80 271.1 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 zf-U11-48K PF05253.12 PVD32570.1 - 5.6e-17 61.2 9.1 2.3e-08 33.7 2.2 2.6 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger Gcn1_N PF12074.8 PVD32570.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Gb3_synth PF04572.12 PVD32570.1 - 0.078 13.2 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region zf-Di19 PF05605.12 PVD32570.1 - 0.39 11.1 3.3 1.2 9.5 3.3 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Fer2_4 PF13510.6 PVD32571.1 - 0.085 12.9 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF4772 PF15997.5 PVD32572.1 - 1.6e-27 96.4 0.0 4.5e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4772) Tudor_3 PF18115.1 PVD32572.1 - 2.4e-06 27.3 0.0 5.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 PVD32572.1 - 3.8e-05 23.3 0.0 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_2 PF18104.1 PVD32572.1 - 0.00063 19.4 0.1 0.0042 16.7 0.1 2.4 1 1 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 PVD32572.1 - 0.0013 18.6 0.0 0.0046 16.9 0.0 1.9 1 1 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor FOXP-CC PF16159.5 PVD32572.1 - 0.03 15.0 1.1 0.064 13.9 0.1 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF4537 PF15057.6 PVD32572.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) THEG PF14912.6 PVD32573.1 - 2.4e-41 140.0 16.1 2.4e-14 53.5 1.7 5.1 3 2 2 5 5 5 5 Testicular haploid expressed repeat DUF1778 PF08681.11 PVD32573.1 - 0.034 14.0 0.3 3.6 7.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1778) UBD PF16455.5 PVD32573.1 - 0.16 12.2 0.1 29 4.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding domain RNase_PH PF01138.21 PVD32574.1 - 1.9e-19 70.5 0.0 2.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1601 PF07671.11 PVD32574.1 - 0.046 13.6 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Fe-ADH PF00465.19 PVD32576.1 - 4.1e-101 338.4 0.0 4.8e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 PVD32576.1 - 2.1e-09 37.4 0.0 7.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ion_trans_2 PF07885.16 PVD32577.1 - 4.2e-06 26.6 0.2 3.1e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans_2 PF07885.16 PVD32578.1 - 7.1e-24 83.6 12.9 1.8e-15 56.6 7.9 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 PVD32578.1 - 0.02 14.1 6.1 0.12 11.6 7.0 1.7 1 1 1 2 2 2 0 Ion transport protein Oxidored_q2 PF00420.24 PVD32578.1 - 0.73 9.5 5.7 1.9 8.2 0.1 2.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Peptidase_C1 PF00112.23 PVD32579.1 - 3.3e-128 426.2 24.8 3.3e-69 233.3 7.9 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Propeptide_C1 PF08127.13 PVD32579.1 - 3.2e-25 87.7 0.3 1.8e-11 43.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PVD32579.1 - 0.00017 20.5 7.7 0.31 9.8 0.1 4.0 4 0 0 4 4 4 2 Peptidase C1-like family Peptidase_M24_C PF16188.5 PVD32579.1 - 0.003 17.6 0.0 4 7.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal region of peptidase_M24 DUF2237 PF09996.9 PVD32579.1 - 0.0086 16.1 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2237) FAM101 PF15068.6 PVD32579.1 - 0.044 13.7 0.8 8.8 6.2 0.1 2.2 2 0 0 2 2 2 0 FAM101 family SecA_PP_bind PF01043.20 PVD32579.1 - 0.072 13.8 0.0 6.3 7.5 0.0 2.5 2 0 0 2 2 2 0 SecA preprotein cross-linking domain CdiI_N PF18228.1 PVD32579.1 - 0.086 12.7 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 CdiI N-terminal domain Ribosomal_L12 PF00542.19 PVD32579.1 - 0.19 12.1 0.0 17 5.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Peptidase_C1 PF00112.23 PVD32580.1 - 5.5e-67 226.0 4.8 5.5e-67 226.0 4.8 1.3 2 0 0 2 2 2 1 Papain family cysteine protease Propeptide_C1 PF08127.13 PVD32580.1 - 1.4e-12 47.2 0.1 5.2e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PVD32580.1 - 0.0011 17.8 0.7 0.8 8.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family RIO1 PF01163.22 PVD32581.1 - 3.3e-61 206.2 0.1 7e-61 205.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PVD32581.1 - 0.0011 18.4 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PVD32581.1 - 0.0023 17.9 0.7 0.015 15.2 0.7 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RFC1 PF08519.12 PVD32582.1 - 7.4e-59 198.4 0.0 2.7e-58 196.6 0.0 2.1 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 PVD32582.1 - 3.7e-15 56.1 0.0 1.3e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 PVD32582.1 - 1.3e-13 51.5 0.0 8.9e-13 48.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD32582.1 - 2.2e-06 28.0 0.0 3.8e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PVD32582.1 - 0.00043 20.3 0.3 0.0035 17.3 0.1 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 PVD32582.1 - 0.00071 19.3 0.0 0.0025 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 PVD32582.1 - 0.00078 19.8 0.0 0.0032 17.8 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_16 PF13191.6 PVD32582.1 - 0.0012 19.2 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain PTCB-BRCT PF12738.7 PVD32582.1 - 0.012 15.5 0.0 0.045 13.7 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 PVD32582.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PVD32582.1 - 0.018 15.1 0.0 0.067 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PVD32582.1 - 0.037 14.4 0.2 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PVD32582.1 - 0.041 14.0 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PVD32582.1 - 0.095 13.1 0.0 0.57 10.6 0.0 2.5 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 PVD32582.1 - 0.14 12.7 2.1 0.55 10.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain TraY PF05509.11 PVD32582.1 - 1.7 8.7 5.8 4.5 7.4 0.1 3.2 3 0 0 3 3 3 0 TraY domain PDZ PF00595.24 PVD32583.1 - 6.2e-69 228.4 7.7 5.4e-19 68.3 0.1 4.6 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 PVD32583.1 - 4.3e-38 128.9 41.6 1.5e-09 37.5 1.0 6.6 3 1 2 6 6 6 6 Leucine rich repeat PDZ_6 PF17820.1 PVD32583.1 - 8e-32 108.9 4.4 1.2e-07 31.5 0.2 4.6 4 0 0 4 4 4 4 PDZ domain LRR_4 PF12799.7 PVD32583.1 - 2.9e-27 94.3 46.3 2.2e-05 24.7 0.0 9.7 6 3 7 13 13 13 11 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 PVD32583.1 - 5.4e-20 71.5 4.6 1.3e-05 25.4 0.4 5.2 4 1 1 5 5 5 4 PDZ domain LRR_9 PF14580.6 PVD32583.1 - 3.2e-10 39.8 19.2 0.00042 19.9 1.3 4.8 2 2 4 6 6 6 3 Leucine-rich repeat Kinesin_assoc PF16183.5 PVD32583.1 - 0.13 12.4 6.5 0.25 11.5 0.3 3.4 3 0 0 3 3 3 0 Kinesin-associated LRR_6 PF13516.6 PVD32583.1 - 0.87 9.8 18.5 78 3.7 0.1 8.2 8 0 0 8 8 8 0 Leucine Rich repeat PCNP PF15473.6 PVD32583.1 - 3.2 8.5 12.8 3.7 8.3 3.5 3.5 3 0 0 3 3 3 0 PEST, proteolytic signal-containing nuclear protein family CENP-H PF05837.12 PVD32584.1 - 0.00088 19.7 7.3 0.00088 19.7 7.3 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) APG6_N PF17675.1 PVD32584.1 - 0.00093 19.7 8.6 0.00093 19.7 8.6 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF334 PF03904.13 PVD32584.1 - 0.0016 18.0 2.8 0.0016 18.0 2.8 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF334) KASH_CCD PF14662.6 PVD32584.1 - 0.0099 15.7 8.8 0.0099 15.7 8.8 1.8 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 PVD32584.1 - 0.025 14.8 6.5 0.025 14.8 6.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Antimicrobial_6 PF08036.11 PVD32584.1 - 0.11 12.6 0.5 0.18 11.9 0.5 1.4 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide DUF2203 PF09969.9 PVD32584.1 - 0.29 11.8 7.3 0.3 11.8 3.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 PVD32584.1 - 0.96 10.1 9.5 0.94 10.2 4.4 2.7 3 0 0 3 3 2 0 Initiation control protein YabA IFT20 PF14931.6 PVD32584.1 - 3.2 7.9 12.4 10 6.3 8.2 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF948 PF06103.11 PVD32584.1 - 3.5 8.0 5.7 7.1 7.0 3.3 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 PVD32584.1 - 3.8 7.9 16.5 15 6.0 16.5 1.9 1 1 0 1 1 1 0 Fez1 ERM PF00769.19 PVD32584.1 - 4 7.2 19.1 10 5.8 18.6 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 PVD32584.1 - 5.5 7.4 15.1 1.5 9.2 9.8 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 PVD32584.1 - 7.4 7.1 17.8 53 4.4 0.0 4.5 4 1 0 4 4 4 0 Cell division protein ZapB Spc7 PF08317.11 PVD32584.1 - 8.8 5.1 17.2 1.5 7.6 11.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 PVD32586.1 - 0.014 15.0 6.9 0.014 15.0 6.9 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FliD_N PF02465.18 PVD32586.1 - 0.015 16.0 12.2 0.8 10.4 0.4 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.9 PVD32586.1 - 0.022 14.8 9.5 0.042 13.9 5.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 PVD32586.1 - 0.025 14.7 4.8 0.028 14.6 2.4 2.1 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Cep57_CLD_2 PF14197.6 PVD32586.1 - 0.026 14.6 6.0 0.026 14.6 6.0 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Bacillus_HBL PF05791.11 PVD32586.1 - 0.03 14.1 4.9 0.054 13.3 4.9 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 PVD32586.1 - 0.063 13.7 13.3 0.6 10.5 12.4 2.4 1 1 1 2 2 2 0 Fez1 DUF641 PF04859.12 PVD32586.1 - 0.093 13.1 8.8 0.13 12.6 6.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Rep_fac_C PF08542.11 PVD32586.1 - 0.096 13.1 0.7 0.34 11.3 0.1 2.3 2 1 1 3 3 2 0 Replication factor C C-terminal domain Spc7 PF08317.11 PVD32586.1 - 0.15 10.9 14.7 0.29 10.0 14.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.6 PVD32586.1 - 0.16 11.7 17.8 0.2 11.4 4.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) GLTP PF08718.11 PVD32586.1 - 0.18 12.1 3.2 0.42 10.9 2.2 2.1 3 0 0 3 3 2 0 Glycolipid transfer protein (GLTP) TMF_TATA_bd PF12325.8 PVD32586.1 - 0.24 11.6 11.1 1.1 9.5 3.1 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2203 PF09969.9 PVD32586.1 - 0.47 11.2 4.0 1.1 10.0 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 PVD32586.1 - 0.48 10.9 17.5 1.1 9.8 14.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 PVD32586.1 - 0.93 10.1 12.9 0.24 12.0 5.2 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MCU PF04678.13 PVD32586.1 - 1.5 8.9 9.9 11 6.1 9.0 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter TSNAXIP1_N PF15739.5 PVD32586.1 - 1.6 9.1 10.5 0.38 11.1 6.4 2.0 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus BRE1 PF08647.11 PVD32586.1 - 1.9 8.6 18.1 11 6.1 0.2 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 PVD32586.1 - 2.2 8.7 12.5 1.8 9.0 0.1 2.7 1 1 0 2 2 2 0 Centromere protein H (CENP-H) USP8_interact PF08941.10 PVD32586.1 - 3.4 7.5 7.9 1.3 8.8 2.2 2.2 2 0 0 2 2 2 0 USP8 interacting POX PF07526.11 PVD32586.1 - 3.8 8.1 12.0 0.31 11.6 0.2 2.3 1 1 0 2 2 2 0 Associated with HOX HIP1_clath_bdg PF16515.5 PVD32586.1 - 3.8 8.2 16.1 8.6 7.0 11.1 2.6 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 PVD32586.1 - 4.3 7.4 18.3 3.7 7.6 9.9 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Hrs_helical PF12210.8 PVD32586.1 - 4.5 7.9 12.4 1.5 9.4 2.8 2.8 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Fib_alpha PF08702.10 PVD32586.1 - 8.1 6.6 13.8 2.7 8.2 9.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 PVD32586.1 - 9.3 6.6 13.5 0.75 10.1 7.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 PVD32586.1 - 9.3 6.3 10.0 6 6.9 4.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CARD PF00619.21 PVD32587.1 - 9.2e-10 38.4 0.2 0.0022 18.0 0.0 2.8 3 0 0 3 3 3 2 Caspase recruitment domain CARD_2 PF16739.5 PVD32587.1 - 9.9e-07 28.7 1.1 6.5e-05 22.8 0.1 3.0 2 1 0 2 2 2 1 Caspase recruitment domain Atypical_Card PF18461.1 PVD32587.1 - 0.091 13.0 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Atypical caspase recruitment domain GTF2I PF02946.14 PVD32588.1 - 4.6e-16 58.6 0.0 1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 GTF2I-like repeat HMG_box PF00505.19 PVD32588.1 - 0.16 12.4 0.6 0.48 10.9 0.6 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box CARD PF00619.21 PVD32589.1 - 0.0016 18.4 0.1 0.0083 16.1 0.0 2.0 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 PVD32589.1 - 0.012 15.6 0.1 0.94 9.5 0.0 2.7 3 0 0 3 3 3 0 Caspase recruitment domain Mucin15 PF15672.5 PVD32590.1 - 0.0092 15.5 2.4 0.017 14.6 2.4 1.4 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 HALZ PF02183.18 PVD32590.1 - 0.013 15.8 36.9 0.27 11.5 0.8 7.2 6 1 0 6 6 6 0 Homeobox associated leucine zipper Glyco_tran_WbsX PF14307.6 PVD32590.1 - 7.6 5.9 8.4 1.4 8.3 4.6 1.6 2 0 0 2 2 2 0 Glycosyltransferase WbsX DUF4715 PF15835.5 PVD32590.1 - 9.6 6.3 11.5 0.36 10.9 3.7 2.6 2 2 0 3 3 3 0 Domain of unknown function (DUF4715) DUF5082 PF16888.5 PVD32591.1 - 0.016 15.5 8.3 0.9 9.8 5.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) FlgN PF05130.12 PVD32591.1 - 0.018 15.6 10.9 0.22 12.1 0.4 2.9 2 1 1 3 3 3 0 FlgN protein Adaptin_binding PF10199.9 PVD32591.1 - 3.2 8.4 13.8 14 6.3 0.4 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 APG6_N PF17675.1 PVD32591.1 - 4.6 7.8 17.8 89 3.6 10.3 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 PVD32591.1 - 5.5 6.3 8.7 0.99 8.7 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FliT PF05400.13 PVD32591.1 - 9.3 7.1 12.8 1.3 9.9 6.1 2.8 3 0 0 3 3 3 0 Flagellar protein FliT CARD PF00619.21 PVD32592.1 - 2.1e-08 34.1 0.0 7.3e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain DUF3811 PF11656.8 PVD32592.1 - 0.021 15.2 7.5 0.68 10.3 0.0 3.5 4 0 0 4 4 4 0 YjbD family (DUF3811) FapA PF03961.13 PVD32592.1 - 0.53 8.8 7.2 0.082 11.5 1.7 1.9 1 1 0 2 2 2 0 Flagellar Assembly Protein A ING PF12998.7 PVD32592.1 - 1.1 9.9 14.4 1.9 9.1 5.2 3.5 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding KASH_CCD PF14662.6 PVD32593.1 - 7.1e-08 32.5 46.2 1.5e-06 28.2 20.2 2.5 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Strep_SA_rep PF06696.11 PVD32593.1 - 0.022 14.8 0.6 0.069 13.2 0.6 1.9 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Cep57_CLD_2 PF14197.6 PVD32593.1 - 0.025 14.7 9.7 0.025 14.7 9.7 4.8 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF3450 PF11932.8 PVD32593.1 - 0.06 12.6 31.9 0.083 12.2 10.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 PVD32593.1 - 0.35 10.4 35.3 0.16 11.5 13.0 2.8 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 LPP PF04728.13 PVD32593.1 - 0.44 11.0 14.7 0.95 9.9 3.4 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper YabA PF06156.13 PVD32593.1 - 1.3 9.7 36.8 1.5 9.5 5.8 4.8 2 1 4 6 6 6 0 Initiation control protein YabA GAS PF13851.6 PVD32593.1 - 6.3 6.1 48.7 0.36 10.2 16.8 3.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 PVD32593.1 - 7.6 6.7 43.5 1.6 8.9 0.4 6.4 2 2 4 6 6 6 0 bZIP transcription factor WSC PF01822.19 PVD32594.1 - 3.9e-20 71.8 18.9 4.6e-10 39.5 8.9 2.2 2 0 0 2 2 2 2 WSC domain CC2D2AN-C2 PF15625.6 PVD32594.1 - 0.038 13.7 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain WSC PF01822.19 PVD32595.1 - 2.8e-13 49.9 14.9 3.7e-09 36.6 4.7 2.5 2 0 0 2 2 2 2 WSC domain Lectin_C PF00059.21 PVD32595.1 - 5.4e-08 33.5 0.0 2.2e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 PVD32595.1 - 0.0029 17.3 0.1 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Sushi PF00084.20 PVD32596.1 - 1.2e-09 38.6 3.4 0.00016 22.2 0.3 2.4 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) WSC PF01822.19 PVD32596.1 - 4.5e-09 36.4 3.9 1.3e-08 35.0 3.9 1.8 1 0 0 1 1 1 1 WSC domain DERM PF14704.6 PVD32596.1 - 0.0097 16.4 0.5 0.016 15.7 0.5 1.4 1 0 0 1 1 1 1 Dermatopontin MIP PF00230.20 PVD32597.1 - 4.8e-06 26.5 0.2 6.5e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 PVD32598.1 - 4.5e-37 127.9 9.3 5.5e-37 127.7 9.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF5518 PF17647.1 PVD32598.1 - 0.64 10.2 15.3 1.4 9.1 12.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5518) ECF_trnsprt PF12822.7 PVD32598.1 - 0.99 9.5 10.0 1.8 8.7 10.0 1.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component ARD PF03079.14 PVD32599.1 - 7.1e-54 182.2 0.0 8.3e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 PVD32599.1 - 2.9e-09 36.5 0.0 4.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 PVD32599.1 - 3.5e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 PVD32599.1 - 0.0028 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 PVD32599.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_6 PF12852.7 PVD32599.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 PVD32599.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Ank_2 PF12796.7 PVD32600.1 - 3.4e-48 162.2 0.7 1.5e-20 73.6 0.1 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD32600.1 - 1.1e-37 127.9 4.5 8.4e-11 42.2 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD32600.1 - 1.8e-32 107.7 3.5 7.9e-05 22.8 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 PVD32600.1 - 2.3e-32 110.0 1.7 1.4e-05 25.3 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PVD32600.1 - 7.1e-28 96.3 7.2 9.3e-11 41.8 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Plasmodium_Vir PF05795.11 PVD32600.1 - 1.4 8.3 6.5 2.2 7.6 6.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BIRC6 PF12356.8 PVD32600.1 - 1.4 8.3 7.9 3.6 7.0 7.9 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 UDPGT PF00201.18 PVD32601.1 - 2.7e-52 178.2 0.0 9.6e-51 173.1 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD32601.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CARD PF00619.21 PVD32602.1 - 5.6e-10 39.1 0.1 1.5e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Caspase recruitment domain CRAL_TRIO PF00650.20 PVD32603.1 - 3.6e-32 111.3 0.2 6e-32 110.6 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PVD32603.1 - 2.4e-06 27.7 0.1 5.7e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PVD32603.1 - 9.8e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EphA2_TM PF14575.6 PVD32603.1 - 0.1 13.5 1.4 1.5 9.8 1.6 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 PVD32603.1 - 0.13 12.1 9.9 0.26 11.2 9.9 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 AlbA_2 PF04326.14 PVD32604.1 - 0.00076 19.8 1.0 0.0016 18.7 0.0 2.1 3 0 0 3 3 3 1 Putative DNA-binding domain NusG_II PF07009.11 PVD32604.1 - 0.056 13.6 1.8 0.081 13.1 0.1 2.2 2 0 0 2 2 2 0 NusG domain II APG6_N PF17675.1 PVD32604.1 - 0.33 11.5 7.5 0.84 10.2 6.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Zn-ribbon_8 PF09723.10 PVD32605.1 - 0.039 14.1 2.9 0.039 14.1 2.9 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Reprolysin_5 PF13688.6 PVD32605.1 - 0.05 13.8 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 PBP PF01161.20 PVD32606.1 - 9e-16 58.4 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 PVD32607.1 - 2.5e-17 63.4 0.2 3.2e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 7tm_1 PF00001.21 PVD32609.1 - 9e-09 35.0 6.6 1.3e-08 34.5 6.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Synaptobrevin PF00957.21 PVD32609.1 - 0.16 11.8 0.6 0.62 9.9 0.1 2.1 2 0 0 2 2 2 0 Synaptobrevin DEDD_Tnp_IS110 PF01548.17 PVD32609.1 - 0.19 11.6 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Transposase TMEM40 PF15817.5 PVD32609.1 - 0.91 9.3 3.5 4.9 7.0 3.5 2.1 1 1 0 1 1 1 0 Transmembrane protein 40 family EF-hand_7 PF13499.6 PVD32611.1 - 1.6e-15 57.3 0.9 8.8e-08 32.5 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD32611.1 - 1.9e-12 46.0 0.5 1.7e-05 24.4 0.1 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PVD32611.1 - 2.6e-11 42.2 1.2 1.5e-06 27.3 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD32611.1 - 1e-06 28.5 0.7 5.3e-06 26.2 0.6 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD32611.1 - 1.8e-06 27.2 0.3 6.7e-05 22.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 PVD32611.1 - 4e-06 27.0 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 PVD32611.1 - 0.0033 17.2 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 EF hand DUF4576 PF15144.6 PVD32611.1 - 0.065 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Claudin_2 PF13903.6 PVD32612.1 - 0.015 15.1 1.5 0.043 13.6 0.5 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD32612.1 - 0.015 15.2 0.7 0.057 13.3 0.4 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family zf-H2C2_2 PF13465.6 PVD32613.1 - 1.6e-20 72.5 40.0 3.4e-06 27.2 2.6 5.9 5 1 1 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD32613.1 - 9.3e-16 57.3 54.2 0.00011 22.5 0.5 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD32613.1 - 5.7e-12 45.4 49.0 0.0016 19.1 0.4 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD32613.1 - 8.2e-09 35.5 31.7 0.027 14.7 1.4 5.9 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PVD32613.1 - 0.092 12.6 13.2 1.5 8.7 6.1 4.1 1 1 3 4 4 4 0 GAGA factor PyrI_C PF02748.15 PVD32613.1 - 0.11 12.5 12.2 11 6.0 0.1 4.5 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 PVD32613.1 - 0.21 12.0 37.8 0.45 11.0 1.9 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 PVD32613.1 - 1.5 8.8 5.4 0.24 11.4 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type BolA PF01722.18 PVD32613.1 - 3 8.2 7.2 9.1 6.6 0.9 3.1 1 1 2 3 3 3 0 BolA-like protein ACOX PF01756.19 PVD32614.1 - 1.3e-58 197.5 0.7 2.7e-58 196.5 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 PVD32614.1 - 9.6e-21 74.6 0.3 1.9e-20 73.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 PVD32614.1 - 1.7e-07 31.4 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PVD32614.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD32614.1 - 0.053 14.2 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Mlh1_C PF16413.5 PVD32614.1 - 0.12 11.7 0.6 0.31 10.4 0.2 1.7 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus ACOX PF01756.19 PVD32615.1 - 6.8e-61 205.0 3.8 1.2e-59 201.0 1.1 2.2 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 PVD32615.1 - 2e-22 80.1 0.3 4.5e-22 78.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 PVD32615.1 - 2.8e-11 43.4 0.0 6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD32615.1 - 2e-05 25.2 0.4 8.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 PVD32615.1 - 0.0023 18.1 0.2 0.0074 16.5 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NodZ PF05830.11 PVD32621.1 - 0.002 17.0 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Glyco_transf_11 PF01531.16 PVD32621.1 - 0.0029 16.9 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 11 XG_FTase PF03254.13 PVD32621.1 - 0.035 12.7 0.0 0.59 8.7 0.0 2.2 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase GTF2I PF02946.14 PVD32623.1 - 8.4e-10 38.6 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 GTF2I-like repeat SCHIP-1 PF10148.9 PVD32623.1 - 0.0028 17.3 0.5 0.0028 17.3 0.5 2.0 2 0 0 2 2 2 1 Schwannomin-interacting protein 1 DUF5308 PF17233.2 PVD32623.1 - 0.071 13.3 3.4 0.17 12.1 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF2193 PF09959.9 PVD32623.1 - 0.2 10.1 4.7 0.72 8.2 0.8 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2193) FmiP_Thoc5 PF09766.9 PVD32623.1 - 7 5.8 10.1 6.6 5.9 0.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Ig_3 PF13927.6 PVD32624.1 - 9.9e-06 26.1 1.3 0.1 13.2 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain TMEM154 PF15102.6 PVD32624.1 - 0.0019 18.1 0.2 0.0043 17.0 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family I-set PF07679.16 PVD32624.1 - 0.0062 16.6 0.4 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 PVD32624.1 - 0.036 14.3 0.6 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin V-set domain Glycophorin_A PF01102.18 PVD32624.1 - 0.071 13.4 0.4 0.071 13.4 0.4 1.8 2 0 0 2 2 2 0 Glycophorin A MLANA PF14991.6 PVD32624.1 - 0.53 10.6 3.3 0.63 10.3 0.5 2.1 1 1 1 2 2 2 0 Protein melan-A C2-set_2 PF08205.12 PVD32625.1 - 8.1e-07 29.0 4.2 0.36 10.9 1.0 4.6 3 2 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 PVD32625.1 - 1.2e-05 25.5 3.2 0.011 16.1 0.3 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 PVD32625.1 - 0.00046 20.3 4.8 0.034 14.3 0.1 4.3 4 1 1 5 5 5 1 Immunoglobulin domain Ig_3 PF13927.6 PVD32625.1 - 0.0012 19.4 5.5 0.029 15.0 0.2 3.4 4 0 0 4 4 4 2 Immunoglobulin domain SKG6 PF08693.10 PVD32626.1 - 0.0086 15.5 2.5 0.017 14.5 2.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain C2-set_2 PF08205.12 PVD32626.1 - 0.018 15.1 8.3 6 7.0 0.9 5.0 3 2 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Adeno_E3_CR2 PF02439.15 PVD32626.1 - 0.29 10.9 2.0 0.69 9.7 2.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1943 PF09172.11 PVD32627.1 - 0.018 14.3 0.1 0.022 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) HMG_box PF00505.19 PVD32627.1 - 0.2 12.1 7.0 0.21 12.0 2.8 2.8 2 1 0 2 2 2 0 HMG (high mobility group) box HMG_box PF00505.19 PVD32628.1 - 4.4 7.8 8.6 0.44 11.0 2.5 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box TGFb_propeptide PF00688.18 PVD32629.1 - 1.5e-37 129.7 0.0 1.9e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 PVD32629.1 - 3.5e-28 98.6 0.2 6.3e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD32630.1 - 1.2e-54 185.6 0.9 6.5e-54 183.3 0.9 1.9 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 PVD32630.1 - 1.4e-35 122.4 0.1 2.7e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain FAD_binding_2 PF00890.24 PVD32631.1 - 1.5e-89 301.0 0.1 2.2e-89 300.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 PVD32631.1 - 1.7e-38 131.5 0.0 2.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term BAG PF02179.16 PVD32632.1 - 1e-17 64.3 2.7 1.8e-17 63.5 2.7 1.4 1 0 0 1 1 1 1 BAG domain WW PF00397.26 PVD32632.1 - 2.7e-11 43.4 2.4 5.5e-11 42.4 2.4 1.6 1 0 0 1 1 1 1 WW domain COPIIcoated_ERV PF07970.12 PVD32633.1 - 1.1e-94 316.5 3.2 1.4e-94 316.1 3.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PVD32633.1 - 6.3e-33 113.0 0.0 1.5e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RDD PF06271.12 PVD32634.1 - 1.7e-10 41.3 2.4 3.8e-09 36.9 2.4 2.1 1 1 0 1 1 1 1 RDD family DUF5432 PF17497.2 PVD32634.1 - 0.12 12.4 0.9 6.1 7.0 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5432) AAT PF03417.16 PVD32635.1 - 1.7e-27 96.6 0.0 2.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase bZIP_2 PF07716.15 PVD32636.1 - 3.4e-05 23.8 9.6 5.4e-05 23.2 9.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD32636.1 - 6.4e-05 23.0 7.1 0.00011 22.3 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1367 PF07105.11 PVD32636.1 - 0.16 11.6 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) zf-RING_UBOX PF13445.6 PVD32637.1 - 3.4e-10 39.8 5.6 3.4e-10 39.8 5.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD32637.1 - 3.9e-08 33.3 10.6 8.3e-08 32.3 10.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD32637.1 - 8.2e-07 28.8 10.7 2.7e-06 27.1 10.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD32637.1 - 3.5e-06 26.8 10.3 7e-06 25.8 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD32637.1 - 6.6e-06 26.4 11.3 1.3e-05 25.5 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD32637.1 - 4.9e-05 23.1 9.8 0.00013 21.8 9.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD32637.1 - 0.00018 21.4 9.9 0.00038 20.3 9.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 PVD32637.1 - 0.014 15.2 8.9 0.047 13.5 9.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 PVD32637.1 - 0.026 14.4 4.1 0.049 13.5 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 PVD32637.1 - 0.051 13.4 10.0 0.75 9.7 10.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PVD32637.1 - 0.053 13.4 1.1 0.12 12.3 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PBP1_TM PF14812.6 PVD32637.1 - 0.073 13.5 0.5 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-RING_11 PF17123.5 PVD32637.1 - 0.1 12.4 3.0 0.26 11.1 3.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger U-box PF04564.15 PVD32637.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain FYVE PF01363.21 PVD32637.1 - 3.1 8.0 6.1 7.9 6.7 5.5 2.0 1 1 1 2 2 2 0 FYVE zinc finger Oxysterol_BP PF01237.18 PVD32638.1 - 2e-128 428.4 0.0 3.3e-128 427.7 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 PVD32638.1 - 1e-06 28.8 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD32638.1 - 4.1e-06 27.0 0.1 0.00018 21.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PVD32638.1 - 7.8e-06 26.4 0.1 1.8e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD32638.1 - 1.2e-05 25.8 0.0 6.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD32638.1 - 0.00013 22.1 0.2 0.0012 19.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat EF-hand_7 PF13499.6 PVD32639.1 - 6e-32 109.9 2.9 2.3e-16 60.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD32639.1 - 8.7e-30 100.0 10.5 1.5e-08 33.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD32639.1 - 1.1e-24 84.2 4.7 2.4e-08 33.2 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PVD32639.1 - 1.9e-24 85.2 7.5 8.7e-11 41.5 1.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PVD32639.1 - 4.1e-22 76.6 5.8 1.9e-06 27.1 0.2 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 PVD32639.1 - 4.1e-07 30.3 0.8 0.0025 18.1 0.2 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PVD32639.1 - 4.6e-06 26.9 0.1 0.053 13.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 PVD32639.1 - 0.00039 20.3 3.8 0.0044 16.9 1.4 2.1 1 1 1 2 2 2 2 SurA N-terminal domain EF-hand_10 PF14788.6 PVD32639.1 - 0.0025 17.6 3.3 0.021 14.7 0.2 3.2 2 2 2 4 4 4 1 EF hand EF-hand_14 PF17959.1 PVD32639.1 - 0.0029 17.9 0.9 1.6 9.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 PVD32639.1 - 0.006 16.7 4.8 0.17 12.1 1.9 2.9 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_4 PF12763.7 PVD32639.1 - 0.0081 16.1 1.5 1.7 8.6 0.3 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 PVD32639.1 - 0.01 15.7 2.6 0.16 11.8 0.5 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 PVD32639.1 - 0.014 15.3 0.9 15 5.5 0.0 3.2 1 1 2 3 3 3 0 Caleosin related protein DUF853 PF05872.12 PVD32639.1 - 0.027 13.1 0.1 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) B5 PF03484.15 PVD32639.1 - 0.049 13.9 0.0 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain p25-alpha PF05517.12 PVD32639.1 - 0.056 13.6 2.2 0.16 12.1 2.2 1.7 1 1 0 1 1 1 0 p25-alpha DUF3349 PF11829.8 PVD32639.1 - 0.12 13.1 0.2 0.56 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF1456 PF07308.13 PVD32639.1 - 0.13 12.7 1.4 7.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_11 PF08976.11 PVD32639.1 - 0.15 12.9 0.2 0.8 10.6 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain UPF0154 PF03672.13 PVD32639.1 - 0.17 11.9 0.7 24 5.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF1296 PF06972.11 PVD32639.1 - 0.17 12.0 1.3 0.61 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Ldl_recept_a PF00057.18 PVD32640.1 - 4.7e-43 145.1 97.3 1e-10 41.7 7.5 7.0 6 1 1 7 7 7 6 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 PVD32640.1 - 2.5e-39 135.4 0.0 5.6e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 PVD32640.1 - 7.8e-10 39.2 2.7 7.8e-10 39.2 2.7 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 PVD32640.1 - 0.002 18.5 0.5 0.0058 17.0 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD32640.1 - 0.0055 17.6 0.0 0.018 15.9 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf_Rg PF17915.1 PVD32642.1 - 0.067 12.6 3.4 4.5 6.7 0.1 3.1 3 0 0 3 3 3 0 Reverse gyrase zinc finger XendoU PF09412.10 PVD32643.1 - 1.7e-20 73.4 0.0 2.1e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU GATA PF00320.27 PVD32644.1 - 7.7e-15 54.2 2.8 1.4e-14 53.4 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 PVD32644.1 - 0.054 13.0 1.1 0.09 12.3 1.1 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding ZU5 PF00791.20 PVD32647.1 - 0.00068 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain ZU5 PF00791.20 PVD32648.1 - 7.6e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain LRAT PF04970.13 PVD32649.1 - 3.7e-11 43.4 0.1 5.9e-10 39.5 0.1 2.1 1 1 0 1 1 1 1 Lecithin retinol acyltransferase C1q PF00386.21 PVD32650.1 - 1.5e-17 64.0 0.2 2.4e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 C1q domain TPR_5 PF12688.7 PVD32650.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat Exo_endo_phos PF03372.23 PVD32651.1 - 3.2e-06 26.8 0.0 6.8e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 PVD32651.1 - 8.3e-06 25.5 0.1 1.9e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PVD32651.1 - 0.0001 22.1 4.6 0.0003 20.6 0.2 3.1 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase CYLD_phos_site PF16607.5 PVD32651.1 - 0.022 14.6 0.2 0.051 13.4 0.2 1.7 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured Exonuc_VII_L PF02601.15 PVD32651.1 - 0.54 9.8 6.0 1.1 8.8 6.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit C1q PF00386.21 PVD32652.1 - 5.3e-16 59.0 0.3 8.3e-16 58.4 0.3 1.3 1 0 0 1 1 1 1 C1q domain KASH_CCD PF14662.6 PVD32652.1 - 0.0062 16.4 0.1 0.0084 16.0 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH BclA_C PF18573.1 PVD32652.1 - 0.0063 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 BclA C-terminal domain CBM_35 PF16990.5 PVD32652.1 - 0.033 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) HALZ PF02183.18 PVD32652.1 - 0.48 10.7 1.0 18 5.7 0.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper LPP PF04728.13 PVD32652.1 - 0.6 10.5 2.6 2.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper VWA PF00092.28 PVD32653.1 - 1.6e-32 113.1 1.2 2.4e-32 112.6 1.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD32653.1 - 3.2e-18 65.6 17.9 8.9e-06 25.8 0.5 3.8 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain VWA_2 PF13519.6 PVD32653.1 - 5.1e-11 43.2 0.3 1.2e-10 42.0 0.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD32653.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 PVD32653.1 - 0.047 13.1 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Copine Cylicin_N PF15241.6 PVD32653.1 - 0.12 12.5 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Cylicin N-terminus Monooxygenase_B PF04744.12 PVD32653.1 - 0.14 10.9 0.4 2.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Monooxygenase subunit B protein EF-hand_1 PF00036.32 PVD32656.1 - 4.4e-13 47.7 6.0 2e-06 26.9 1.7 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD32656.1 - 6e-12 44.5 4.3 4.1e-07 29.4 1.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PVD32656.1 - 2.3e-11 43.9 3.7 7.5e-08 32.7 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD32656.1 - 1.8e-07 30.3 1.1 0.00055 19.3 0.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD32656.1 - 5.9e-06 26.0 8.2 0.02 14.8 1.5 3.9 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD32656.1 - 0.0042 17.4 0.9 0.0097 16.2 0.9 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Syntaxin PF00804.25 PVD32656.1 - 0.0099 15.6 1.5 0.021 14.5 1.3 1.6 2 0 0 2 2 2 1 Syntaxin UPF0154 PF03672.13 PVD32656.1 - 0.051 13.6 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Glyco_hydro_18 PF00704.28 PVD32657.1 - 6.3e-72 242.9 0.1 8.5e-72 242.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD32657.1 - 1.4e-10 41.2 0.7 2.4e-10 40.4 0.7 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF4849 PF16141.5 PVD32657.1 - 0.017 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 Glyco_hydro_18 PF00704.28 PVD32658.1 - 7.4e-71 239.4 0.1 8.9e-71 239.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD32658.1 - 0.0002 21.5 0.5 0.00041 20.5 0.5 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain MIR PF02815.19 PVD32661.1 - 1.3e-16 61.0 1.4 1e-11 45.0 0.1 2.1 1 1 1 2 2 2 2 MIR domain CAMSAP_CH PF11971.8 PVD32662.1 - 1.2e-26 92.4 0.1 2.5e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 PVD32662.1 - 3.2e-16 58.9 7.0 3.2e-16 58.9 7.0 3.3 2 1 1 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.31 PVD32662.1 - 0.11 12.6 0.2 0.34 11.1 0.2 1.8 1 1 0 1 1 1 0 Calponin homology (CH) domain CAMSAP_CKK PF08683.11 PVD32663.1 - 1.3e-54 183.5 0.1 2e-54 182.8 0.1 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF1324 PF07038.11 PVD32663.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) zf-met PF12874.7 PVD32664.1 - 4.3e-19 68.2 13.1 5.5e-07 29.8 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD32664.1 - 7.2e-14 51.7 8.8 8e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 PVD32664.1 - 2.1e-13 49.8 6.0 0.00019 21.2 0.3 3.4 3 0 0 3 3 3 3 U1 zinc finger zf-C2H2_2 PF12756.7 PVD32664.1 - 1.8e-05 25.0 10.6 0.16 12.3 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 PVD32664.1 - 0.00026 21.2 6.5 0.11 12.7 0.1 3.1 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) Fer2 PF00111.27 PVD32664.1 - 0.021 14.8 0.3 9.5 6.3 0.0 3.4 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain zf-C2H2_4 PF13894.6 PVD32664.1 - 0.03 15.1 5.2 2.2 9.3 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger OTT_1508_deam PF14441.6 PVD32664.1 - 0.034 14.1 4.2 7.3 6.7 0.1 3.2 3 0 0 3 3 3 0 OTT_1508-like deaminase zf-MYST PF17772.1 PVD32664.1 - 0.052 13.2 4.7 0.47 10.1 0.1 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 PVD32664.1 - 0.087 12.7 3.9 1.2 9.0 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-SCNM1 PF15803.5 PVD32664.1 - 0.13 11.9 0.2 0.13 11.9 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 OrsD PF12013.8 PVD32664.1 - 0.25 11.8 6.8 4.2 7.8 3.5 2.8 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DZR PF12773.7 PVD32664.1 - 2.1 8.5 5.9 4.7 7.3 2.6 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 PVD32664.1 - 4.5 7.0 7.3 24 4.7 0.4 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HIPIP PF01355.17 PVD32664.1 - 5.8 7.3 6.3 3 8.3 0.3 2.9 3 1 0 3 3 3 0 High potential iron-sulfur protein Eapp_C PF10238.9 PVD32664.1 - 8 6.5 9.9 9.1 6.3 0.1 2.4 2 1 0 2 2 2 0 E2F-associated phosphoprotein JAB PF01398.21 PVD32665.1 - 1.6e-32 111.9 0.0 3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PVD32665.1 - 4.6e-15 56.0 0.7 7.8e-15 55.3 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 PVD32665.1 - 2.4e-06 27.3 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NKAIN PF05640.14 PVD32666.1 - 1.8e-60 203.8 5.7 3.7e-60 202.7 4.3 2.0 2 0 0 2 2 2 1 Na,K-Atpase Interacting protein HATPase_c_3 PF13589.6 PVD32666.1 - 3.9e-12 46.2 0.0 1.3e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_hinge PF06470.13 PVD32666.1 - 2.3e-08 34.3 0.0 5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain HATPase_c PF02518.26 PVD32666.1 - 8.2e-05 23.1 0.0 0.00038 20.9 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Terminase_4 PF05119.12 PVD32666.1 - 0.11 13.0 0.3 0.37 11.2 0.3 1.8 1 0 0 1 1 1 0 Phage terminase, small subunit SF-assemblin PF06705.11 PVD32666.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 SF-assemblin/beta giardin 7tm_1 PF00001.21 PVD32668.1 - 1.7e-18 66.9 6.3 2.9e-18 66.2 6.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD32668.1 - 3.8e-14 52.7 7.6 5e-14 52.3 7.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw MACPF PF01823.19 PVD32671.1 - 4e-20 72.8 0.0 5.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain PAN_3 PF08277.12 PVD32671.1 - 0.00082 19.1 5.1 0.0013 18.5 3.7 2.1 2 1 0 2 2 2 1 PAN-like domain NOB1_Zn_bind PF08772.11 PVD32671.1 - 0.16 12.2 4.1 0.34 11.1 4.1 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF3694 PF12473.8 PVD32672.1 - 4.2e-27 95.7 0.0 1.4e-26 94.0 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein CAP_GLY PF01302.25 PVD32672.1 - 3.5e-25 87.8 0.5 6.4e-25 86.9 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain KIF1B PF12423.8 PVD32672.1 - 4.9e-16 58.9 0.1 2.2e-15 56.8 0.1 2.3 1 0 0 1 1 1 1 Kinesin protein 1B DUF3585 PF12130.8 PVD32672.1 - 0.0075 16.4 4.3 0.0075 16.4 4.3 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain OmpH PF03938.14 PVD32672.1 - 1.1 9.6 9.1 0.42 10.9 0.4 2.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rootletin PF15035.6 PVD32672.1 - 1.5 8.8 12.2 0.055 13.5 1.9 2.9 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Kinesin PF00225.23 PVD32673.1 - 3.7e-46 157.6 0.0 6.5e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 PVD32673.1 - 2.9e-29 102.5 5.9 3.3e-20 73.0 0.8 2.4 1 1 1 2 2 2 2 Kinesin-associated FHA PF00498.26 PVD32673.1 - 4.2e-07 30.2 0.1 1.7e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PVD32673.1 - 8.3e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ExsD PF16806.5 PVD32673.1 - 0.0067 16.4 0.4 0.0099 15.8 0.4 1.2 1 0 0 1 1 1 1 Antiactivator protein ExsD FAM76 PF16046.5 PVD32673.1 - 0.08 12.3 0.7 0.12 11.8 0.7 1.2 1 0 0 1 1 1 0 FAM76 protein Noelin-1 PF12308.8 PVD32673.1 - 0.3 11.1 1.6 0.57 10.2 1.6 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein 5_nucleotid PF05761.14 PVD32673.1 - 2.4 6.9 4.5 3.7 6.3 4.5 1.2 1 0 0 1 1 1 0 5' nucleotidase family Tankyrase_bdg_C PF15327.6 PVD32674.1 - 0.17 12.3 8.9 0.086 13.3 4.2 2.6 2 1 0 2 2 2 0 Tankyrase binding protein C terminal domain BSMAP PF12280.8 PVD32674.1 - 0.23 11.6 1.3 0.65 10.2 1.3 1.7 1 0 0 1 1 1 0 Brain specific membrane anchored protein Sarcolipin PF05366.11 PVD32674.1 - 0.53 10.0 2.5 0.97 9.2 2.5 1.3 1 0 0 1 1 1 0 Sarcolipin LRR_8 PF13855.6 PVD32675.1 - 4.6e-40 135.2 17.6 1e-12 47.6 1.2 6.4 2 2 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 PVD32675.1 - 1.5e-18 67.0 0.0 9.3e-09 35.3 0.0 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD32675.1 - 1.2e-13 50.9 23.3 0.0015 18.9 1.9 7.3 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD32675.1 - 7.6e-08 31.9 15.3 0.46 11.2 0.0 9.3 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 PVD32675.1 - 0.0033 16.9 1.1 0.19 11.2 0.0 2.8 1 1 1 3 3 3 1 Leucine-rich repeat TMEM154 PF15102.6 PVD32675.1 - 0.31 10.9 11.2 5.2 7.0 11.2 2.6 1 1 0 1 1 1 0 TMEM154 protein family Kinesin PF00225.23 PVD32676.1 - 4.4e-20 71.9 0.0 4.7e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD32676.1 - 9.9e-13 48.3 0.0 1.1e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding RRM_1 PF00076.22 PVD32677.1 - 7e-63 208.4 2.6 7.3e-22 77.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 PVD32677.1 - 4.4e-30 103.7 0.1 5.3e-29 100.2 0.1 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 PVD32677.1 - 3.9e-08 33.2 0.1 0.27 11.3 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PVD32677.1 - 1.9e-05 24.7 1.0 0.79 9.8 0.1 4.7 4 1 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 PVD32677.1 - 2.9e-05 23.8 0.0 0.0013 18.5 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif SET_assoc PF11767.8 PVD32677.1 - 0.0018 17.8 0.3 19 5.0 0.0 4.3 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 PVD32677.1 - 0.0067 16.5 1.3 3.8 7.6 0.0 3.7 4 1 0 4 4 4 1 RNA binding motif Thioredoxin_3 PF13192.6 PVD32677.1 - 0.069 13.2 0.0 5.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain OB_RNB PF08206.11 PVD32677.1 - 0.075 12.7 5.2 2.2 8.0 0.1 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF4078 PF13300.6 PVD32677.1 - 3 8.2 7.4 32 4.9 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4078) REJ PF02010.15 PVD32678.1 - 3.1e-17 62.5 8.0 6.9e-12 44.9 1.9 3.3 1 1 0 2 2 2 2 REJ domain Y_Y_Y PF07495.13 PVD32678.1 - 3e-11 43.1 0.2 0.18 11.8 0.0 5.4 5 0 0 5 5 5 3 Y_Y_Y domain DUF4625 PF15418.6 PVD32678.1 - 8.9e-10 38.9 0.3 0.074 13.3 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4625) Wzt_C PF14524.6 PVD32678.1 - 1.4e-05 25.2 0.3 1.3 9.1 0.0 4.1 4 0 0 4 4 4 2 Wzt C-terminal domain DUF5013 PF16405.5 PVD32678.1 - 9.7e-05 22.7 2.7 0.99 9.7 0.0 4.3 2 2 0 4 4 4 2 Domain of unknown function (DUF5013) MANEC PF07502.14 PVD32678.1 - 0.00033 20.9 1.0 0.00033 20.9 1.0 3.2 3 0 0 3 3 3 1 MANEC domain He_PIG PF05345.12 PVD32678.1 - 0.0013 18.9 10.7 3.9 7.7 0.1 4.8 5 0 0 5 5 5 3 Putative Ig domain PKD PF00801.20 PVD32678.1 - 0.0046 16.8 13.2 1.1 9.1 0.1 5.8 5 2 0 5 5 5 2 PKD domain Cadherin PF00028.17 PVD32678.1 - 0.01 16.3 2.5 11 6.5 0.0 4.5 5 0 0 5 5 5 0 Cadherin domain DUF5404 PF17397.2 PVD32678.1 - 0.019 15.1 0.1 0.086 13.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5404) DUF5011 PF16403.5 PVD32678.1 - 0.28 11.3 5.2 5.2 7.3 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Cadherin_5 PF17892.1 PVD32678.1 - 0.53 10.3 8.2 58 3.8 0.1 4.5 4 0 0 4 4 4 0 Cadherin-like domain Otopetrin PF03189.13 PVD32679.1 - 1.2e-136 456.1 1.2 1.2e-136 456.1 1.2 1.5 2 0 0 2 2 2 1 Otopetrin AWPM-19 PF05512.11 PVD32679.1 - 0.047 13.9 1.8 0.16 12.1 1.8 2.0 1 0 0 1 1 1 0 AWPM-19-like family DUF2157 PF09925.9 PVD32679.1 - 0.32 10.8 4.4 0.27 11.0 0.8 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Otopetrin PF03189.13 PVD32680.1 - 1.9e-60 204.9 1.4 2.2e-60 204.7 1.4 1.0 1 0 0 1 1 1 1 Otopetrin Fig1 PF12351.8 PVD32680.1 - 0.1 12.5 4.9 0.12 12.2 0.4 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Oxidored_q4 PF00507.19 PVD32680.1 - 6.2 7.0 7.0 0.92 9.7 2.8 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Cu2_monoox_C PF03712.15 PVD32682.1 - 3.3e-08 33.2 0.0 0.0024 17.4 0.0 2.4 1 1 1 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PVD32682.1 - 4e-06 27.1 0.2 0.038 14.2 0.1 2.3 1 1 1 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain GST_N_3 PF13417.6 PVD32683.1 - 5.1e-18 65.3 0.0 9.4e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD32683.1 - 7.3e-17 61.5 0.1 1.7e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD32683.1 - 2.2e-12 47.1 0.0 4.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PVD32683.1 - 2e-05 24.7 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PVD32683.1 - 7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 PVD32683.1 - 0.0003 20.9 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD32683.1 - 0.00059 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0242 PF06785.11 PVD32684.1 - 0.12 12.5 13.1 0.47 10.5 10.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4698 PF15769.5 PVD32685.1 - 2.5e-45 155.5 14.1 6.4e-45 154.1 14.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4698) Polyoma_coat2 PF00761.20 PVD32685.1 - 0.13 12.0 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein RhoGAP PF00620.27 PVD32686.1 - 5.2e-40 136.7 0.3 9e-40 136.0 0.3 1.4 1 0 0 1 1 1 1 RhoGAP domain DEAD PF00270.29 PVD32687.1 - 1.6e-51 174.6 0.1 1.8e-50 171.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD32687.1 - 9.4e-27 93.6 0.3 2.2e-24 85.9 0.3 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 PVD32687.1 - 1.8e-15 56.9 1.8 1.8e-15 56.9 1.8 3.3 4 1 0 4 4 4 1 DBP10CT (NUC160) domain AAA_19 PF13245.6 PVD32687.1 - 0.031 14.6 1.5 0.16 12.3 0.1 2.6 3 0 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 PVD32687.1 - 0.074 13.0 0.9 0.89 9.5 0.0 2.9 3 0 0 3 3 3 0 Flavivirus DEAD domain Maf_N PF08383.11 PVD32687.1 - 0.18 11.6 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 Maf N-terminal region SAND PF01342.21 PVD32689.1 - 3.8e-21 74.6 0.6 1.6e-20 72.6 0.1 2.3 3 0 0 3 3 3 1 SAND domain Sec6 PF06046.13 PVD32690.1 - 4.1e-106 355.6 13.0 7.4e-105 351.5 9.0 2.4 2 1 0 2 2 2 1 Exocyst complex component Sec6 NPV_P10 PF05531.12 PVD32690.1 - 0.022 15.2 0.2 0.099 13.1 0.2 2.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Dynactin_p22 PF07426.11 PVD32690.1 - 0.029 14.2 8.0 0.085 12.7 8.0 1.8 1 0 0 1 1 1 0 Dynactin subunit p22 FUSC PF04632.12 PVD32690.1 - 0.071 11.6 4.7 0.12 10.9 4.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCC_N PF16752.5 PVD32690.1 - 0.15 12.5 2.2 0.4 11.1 0.2 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Sec5 PF15469.6 PVD32690.1 - 0.2 11.5 7.2 0.049 13.5 3.4 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec5 Sec8_exocyst PF04048.14 PVD32690.1 - 0.32 10.9 3.2 0.33 10.8 1.0 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SOAR PF16533.5 PVD32690.1 - 0.7 9.9 4.8 0.64 10.0 0.6 2.6 2 0 0 2 2 2 0 STIM1 Orai1-activating region PH PF00169.29 PVD32691.1 - 8e-40 135.6 0.0 4.3e-19 69.0 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 PVD32691.1 - 2.5e-15 56.8 10.7 1.3e-08 35.2 1.0 4.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 PVD32691.1 - 1.2e-10 41.6 0.3 9.2e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PDZ_6 PF17820.1 PVD32691.1 - 6e-10 38.8 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD32691.1 - 7e-07 29.5 0.2 1.2e-06 28.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 PVD32691.1 - 3.8e-06 27.2 6.4 0.3 11.5 0.2 4.6 3 2 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 PVD32691.1 - 9.7e-06 25.6 0.1 0.0018 18.3 0.0 2.6 3 0 0 3 3 3 1 PH domain PH_15 PF17339.2 PVD32691.1 - 0.0003 20.6 0.3 0.48 10.3 0.0 2.8 3 0 0 3 3 3 2 PH domain PDZ_2 PF13180.6 PVD32691.1 - 0.0026 18.1 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH_6 PF15406.6 PVD32691.1 - 0.0029 17.9 0.0 3.3 8.0 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Tricorn_PDZ PF14685.6 PVD32691.1 - 0.038 14.0 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain PH_13 PF16652.5 PVD32691.1 - 0.14 12.0 1.3 7.2 6.4 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain GCP_C_terminal PF04130.13 PVD32693.1 - 1.1e-21 77.7 1.7 1.1e-21 77.7 1.7 3.6 3 2 1 4 4 4 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PVD32693.1 - 6.9e-17 62.0 0.7 4.9e-09 36.2 0.0 3.0 2 1 1 3 3 3 2 Gamma tubulin complex component N-terminal SBP56 PF05694.11 PVD32694.1 - 2.6e-50 171.6 0.0 3.1e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) SBP56 PF05694.11 PVD32695.1 - 8.6e-162 539.1 0.3 4.2e-138 461.0 0.1 2.0 1 1 1 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 PVD32695.1 - 7.2e-06 25.5 0.0 0.00019 20.8 0.0 2.5 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller Carboxyl_trans PF01039.22 PVD32696.1 - 1.9e-195 650.2 0.0 2.3e-195 649.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PVD32696.1 - 0.068 12.6 0.3 0.6 9.6 0.0 2.4 2 1 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Sulfatase PF00884.23 PVD32698.1 - 4.1e-10 39.6 0.0 8e-05 22.2 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase_C PF14707.6 PVD32698.1 - 0.011 16.5 0.0 0.016 16.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD32698.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Sulfatase PF00884.23 PVD32699.1 - 1.4e-12 47.6 0.1 1.8e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase PF00884.23 PVD32700.1 - 3.1e-53 181.2 0.3 4.1e-53 180.8 0.3 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 PVD32700.1 - 3.5e-06 26.9 0.2 0.056 13.4 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function Phosphodiest PF01663.22 PVD32700.1 - 0.00024 20.8 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 PVD32700.1 - 0.019 15.7 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Strep_pep PF14404.6 PVD32700.1 - 0.77 10.1 3.8 21 5.4 0.0 3.4 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species Condensation PF00668.20 PVD32701.1 - 0.16 10.6 0.1 0.2 10.3 0.1 1.0 1 0 0 1 1 1 0 Condensation domain Ras PF00071.22 PVD32702.1 - 1.5e-27 96.2 0.0 6e-27 94.2 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD32702.1 - 1.3e-08 35.1 0.0 1.3e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32702.1 - 4.2e-06 26.3 0.0 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD32702.1 - 0.0024 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PVD32702.1 - 0.023 15.0 0.0 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PVD32702.1 - 0.024 14.5 0.0 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 PVD32702.1 - 0.03 13.5 0.0 0.091 11.9 0.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 PVD32702.1 - 0.039 13.4 0.0 0.14 11.5 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 PVD32702.1 - 0.053 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 PVD32702.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 PVD32702.1 - 0.17 10.9 0.0 0.6 9.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GST_C PF00043.25 PVD32703.1 - 0.0001 22.5 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD32703.1 - 0.00048 20.1 0.0 0.00089 19.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD32703.1 - 0.0028 17.8 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HAP1_N PF04849.13 PVD32704.1 - 8.8e-09 35.0 7.5 8.8e-09 35.0 7.5 3.4 2 1 0 3 3 3 2 HAP1 N-terminal conserved region Methyltr_RsmB-F PF01189.17 PVD32704.1 - 0.0015 18.3 7.4 0.014 15.0 0.0 3.3 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F DUF1664 PF07889.12 PVD32704.1 - 0.05 13.7 0.7 0.05 13.7 0.7 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) DUF5586 PF17824.1 PVD32705.1 - 0.00015 21.0 0.1 0.00037 19.7 0.0 1.5 1 1 1 2 2 2 1 Family of unknown function (DUF5586) XRCC1_N PF01834.16 PVD32706.1 - 8.1e-35 120.0 0.0 4.3e-34 117.7 0.0 2.0 2 0 0 2 2 2 1 XRCC1 N terminal domain FXMRP1_C_core PF12235.8 PVD32706.1 - 6.3 7.4 9.4 0.46 11.1 2.1 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Sec63 PF02889.16 PVD32707.1 - 8.5e-32 110.3 0.3 1.4e-31 109.6 0.3 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 PVD32707.1 - 2.4e-24 86.0 0.0 9.7e-24 84.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD32707.1 - 7.2e-09 36.0 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD32707.1 - 4.5e-08 33.3 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 PVD32708.1 - 8.9e-28 96.0 7.5 4.7e-07 30.4 1.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32708.1 - 2.5e-11 43.7 0.0 0.21 11.9 0.0 5.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD32708.1 - 0.046 13.0 0.1 0.69 9.2 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain AGTRAP PF06396.11 PVD32709.1 - 1.6e-20 73.4 0.0 1.9e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) SecD_SecF PF02355.16 PVD32709.1 - 0.094 12.1 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein export membrane protein DUF2627 PF11118.8 PVD32709.1 - 0.3 11.7 0.1 0.3 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) 7tm_1 PF00001.21 PVD32713.1 - 0.0014 18.0 0.2 0.69 9.2 0.0 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DNA_pol_phi PF04931.13 PVD32714.1 - 3.2e-105 352.9 26.3 5e-105 352.3 26.3 1.2 1 0 0 1 1 1 1 DNA polymerase phi Roc PF08477.13 PVD32714.1 - 9.3e-06 25.9 0.0 3.1e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD32714.1 - 6.9e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 Ras family TFIIA PF03153.13 PVD32714.1 - 0.012 15.6 7.8 0.028 14.5 7.8 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3300 PF11737.8 PVD32714.1 - 0.1 12.1 0.4 0.23 11.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) SDA1 PF05285.12 PVD32714.1 - 0.28 10.6 15.0 0.54 9.6 15.0 1.4 1 0 0 1 1 1 0 SDA1 DUF1539 PF07560.11 PVD32714.1 - 0.5 10.4 9.5 2.5 8.2 0.4 5.2 6 1 1 7 7 7 0 Domain of Unknown Function (DUF1539) zf-C3HC4_3 PF13920.6 PVD32716.1 - 9.2e-13 47.8 6.3 2.1e-12 46.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD32716.1 - 1.3e-10 41.5 10.8 3.2e-10 40.2 10.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD32716.1 - 1.9e-10 40.6 7.4 1.1e-09 38.1 8.0 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD32716.1 - 2.6e-10 40.0 11.2 2.6e-10 40.0 11.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD32716.1 - 3.5e-10 39.6 10.1 3.5e-10 39.6 10.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD32716.1 - 9.7e-09 35.1 7.2 9.7e-09 35.1 7.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD32716.1 - 2.6e-08 33.6 8.2 1.8e-07 30.9 8.6 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PVD32716.1 - 2.7e-07 30.8 6.8 6.6e-07 29.5 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PVD32716.1 - 3.5e-07 30.3 10.3 8.2e-07 29.1 10.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PVD32716.1 - 5.9e-06 26.1 2.4 1.3e-05 25.0 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PVD32716.1 - 0.00077 19.5 4.2 0.0016 18.4 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 PVD32716.1 - 0.003 17.3 5.3 0.0081 16.0 5.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.12 PVD32716.1 - 0.017 15.4 7.8 0.18 12.1 5.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 PVD32716.1 - 0.029 14.3 6.4 0.052 13.5 6.4 1.4 1 0 0 1 1 1 0 zinc-ribbons Zn_ribbon_17 PF17120.5 PVD32716.1 - 0.04 13.5 5.2 0.095 12.3 5.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 PVD32716.1 - 0.07 13.0 2.7 0.66 9.9 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif GAGA PF09237.11 PVD32716.1 - 0.081 12.7 0.4 8.9 6.2 0.1 2.5 2 0 0 2 2 2 0 GAGA factor TerY_C PF15616.6 PVD32716.1 - 0.086 13.0 0.6 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain UBZ_FAAP20 PF15750.5 PVD32716.1 - 0.088 12.8 1.5 4.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_4 PF14570.6 PVD32716.1 - 0.13 12.1 7.1 1.1 9.1 3.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UreE_C PF05194.12 PVD32716.1 - 0.18 12.3 8.3 0.35 11.4 6.9 2.0 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain CPP1-like PF11833.8 PVD32716.1 - 0.19 11.4 0.5 0.44 10.2 0.5 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-RING_11 PF17123.5 PVD32716.1 - 0.41 10.4 5.8 1.3 8.9 5.8 1.9 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 PVD32716.1 - 0.64 10.1 6.1 2 8.5 6.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 PVD32716.1 - 0.93 9.2 9.3 0.87 9.3 7.1 2.1 2 1 0 2 2 2 0 P-11 zinc finger Zn-C2H2_12 PF18112.1 PVD32716.1 - 1.5 9.3 6.0 20 5.8 0.8 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain SelP_N PF04592.14 PVD32716.1 - 1.8 7.9 6.3 4.1 6.7 6.3 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prok-RING_1 PF14446.6 PVD32716.1 - 2.1 8.4 6.8 26 4.8 3.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3985 PF13153.6 PVD32716.1 - 3.5 7.7 9.2 0.71 9.9 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3985) LRR_9 PF14580.6 PVD32718.1 - 2.2e-09 37.0 0.0 4.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD32718.1 - 4.2e-09 36.0 5.2 1.3e-08 34.5 3.3 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PVD32718.1 - 1.2e-05 25.6 10.1 0.00044 20.6 6.1 3.0 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD32718.1 - 0.013 15.5 5.6 1.6 9.0 1.6 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PVD32718.1 - 1.3 9.8 7.5 25 5.9 1.4 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat HLH PF00010.26 PVD32719.1 - 1.9e-12 46.9 2.8 4.7e-12 45.7 2.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain V_ATPase_I PF01496.19 PVD32719.1 - 0.044 11.7 2.3 0.078 10.9 2.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PNMA PF14893.6 PVD32719.1 - 0.06 12.7 3.9 0.12 11.8 3.9 1.4 1 0 0 1 1 1 0 PNMA SKA1 PF07160.12 PVD32719.1 - 0.21 11.4 10.9 0.025 14.5 6.5 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Phage_GPO PF05929.11 PVD32719.1 - 0.32 10.6 7.9 3.1 7.3 6.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase STIL_N PF15253.6 PVD32719.1 - 0.37 9.7 10.5 0.076 12.0 0.3 2.4 1 1 1 2 2 2 0 SCL-interrupting locus protein N-terminus Fmp27_WPPW PF10359.9 PVD32719.1 - 0.6 8.9 10.3 1 8.1 10.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Methyltrans_Mon PF14314.6 PVD32719.1 - 0.87 7.5 5.1 1.3 7.0 5.1 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase zf-C4H2 PF10146.9 PVD32719.1 - 1.4 9.2 16.5 3.7 7.8 16.5 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 PVD32719.1 - 3 8.4 19.3 0.13 12.8 13.6 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region FapA PF03961.13 PVD32719.1 - 5.8 5.4 7.2 8.8 4.8 7.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMEM219 PF14940.6 PVD32720.1 - 2.6e-48 164.7 0.2 4.4e-48 163.9 0.2 1.4 1 1 0 1 1 1 1 Transmembrane 219 Morc6_S5 PF17942.1 PVD32722.1 - 4e-18 65.8 2.7 2.8e-10 40.4 0.1 2.8 2 1 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 PVD32722.1 - 1.1e-13 50.9 3.7 3e-13 49.5 3.7 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger T-box PF00907.22 PVD32723.1 - 3.2e-23 82.9 0.0 5.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 T-box CAP_N PF01213.19 PVD32723.1 - 4.1 6.8 10.7 7.3 6.0 10.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IRK_C PF17655.1 PVD32727.1 - 3e-55 186.5 0.0 4.1e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PVD32727.1 - 3.9e-23 81.8 0.6 2.5e-20 72.8 0.1 2.3 1 1 1 2 2 2 2 Inward rectifier potassium channel transmembrane domain IRK PF01007.20 PVD32728.1 - 1.6e-43 147.9 0.1 2.4e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 PVD32728.1 - 1e-14 54.5 0.1 1.5e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 PVD32728.1 - 2.8e-05 24.0 3.3 6.7e-05 22.8 3.3 1.6 1 1 0 1 1 1 1 Ion channel IRK_C PF17655.1 PVD32729.1 - 4.8e-18 65.4 0.0 5.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Perm-CXXC PF15629.6 PVD32729.1 - 0.043 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Permuted single zf-CXXC unit IRK_C PF17655.1 PVD32730.1 - 2.8e-54 183.4 0.0 3.8e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PVD32730.1 - 5.6e-14 52.2 0.0 8.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PVD32730.1 - 0.00022 21.1 0.7 0.00035 20.5 0.7 1.3 1 0 0 1 1 1 1 Ion channel zf-C3HC4_3 PF13920.6 PVD32731.1 - 1.3e-07 31.3 8.2 2.3e-07 30.5 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD32731.1 - 1.6e-05 24.7 9.4 3.1e-05 23.8 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD32731.1 - 2.4e-05 24.2 9.6 7.8e-05 22.6 9.7 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD32731.1 - 0.0001 22.1 5.7 0.00018 21.3 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD32731.1 - 0.00025 20.8 9.6 0.0005 19.9 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD32731.1 - 0.00035 20.8 5.3 0.00088 19.5 5.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD32731.1 - 0.0005 20.0 6.0 0.0012 18.9 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD32731.1 - 0.0014 19.0 8.2 0.0029 17.9 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 PVD32731.1 - 0.0057 16.7 1.9 0.011 15.8 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_MLP1_2 PF07926.12 PVD32731.1 - 0.0069 16.5 7.1 0.0069 16.5 7.1 8.6 6 3 2 8 8 6 1 TPR/MLP1/MLP2-like protein zf-C3HC4_4 PF15227.6 PVD32731.1 - 0.044 13.9 6.7 0.1 12.8 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 PVD32731.1 - 0.25 11.0 3.6 0.42 10.3 3.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PVD32731.1 - 4.5 7.2 11.2 3 7.7 5.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain VPS9 PF02204.18 PVD32732.1 - 1.1e-16 60.9 1.3 2.3e-16 59.9 0.4 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Bap31_Bap29_C PF18035.1 PVD32732.1 - 0.0064 16.5 0.1 0.024 14.6 0.1 1.9 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain BORCS8 PF10167.9 PVD32733.1 - 0.061 13.3 0.9 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF684 PF05075.14 PVD32733.1 - 0.12 11.3 0.1 1.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF684) Paramecium_SA PF01508.16 PVD32733.1 - 5.8 7.4 10.5 1.6 9.2 0.5 2.8 2 0 0 2 2 2 0 Paramecium surface antigen domain Copine PF07002.16 PVD32735.1 - 4.4e-62 209.4 0.0 5.7e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 PVD32735.1 - 1.3e-08 35.2 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus CdhC PF03598.15 PVD32735.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Mito_carr PF00153.27 PVD32736.1 - 5.4e-48 160.9 0.3 2.6e-19 68.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tektin PF03148.14 PVD32737.1 - 5.4e-148 492.8 41.4 6.1e-148 492.6 41.4 1.0 1 0 0 1 1 1 1 Tektin family DUF445 PF04286.12 PVD32737.1 - 0.49 10.1 24.1 27 4.4 25.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF948 PF06103.11 PVD32737.1 - 1 9.7 13.7 6.2 7.1 0.1 4.7 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 PVD32737.1 - 1.9 8.5 16.6 0.071 13.1 0.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Phasin PF05597.11 PVD32737.1 - 3.2 7.8 15.5 0.15 12.0 2.9 3.8 2 2 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 PVD32737.1 - 3.2 7.8 14.2 29 4.7 0.2 3.8 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lsr2 PF11774.8 PVD32737.1 - 3.3 7.9 8.4 0.34 11.1 1.4 2.8 2 1 1 3 3 3 0 Lsr2 CelTOS PF18659.1 PVD32737.1 - 5.3 7.5 10.9 0.76 10.2 0.3 3.8 3 1 1 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites Sulfotransfer_1 PF00685.27 PVD32738.1 - 4e-49 167.5 0.0 5e-48 163.9 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32738.1 - 3.8e-09 37.3 0.0 7.2e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Trypsin_2 PF13365.6 PVD32739.1 - 6.7e-07 30.3 0.1 1.3e-06 29.4 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Cofilin_ADF PF00241.20 PVD32740.1 - 2.1e-05 24.3 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_1 PF00667.20 PVD32741.1 - 5.9e-72 241.8 0.0 1e-71 241.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PVD32741.1 - 2.1e-36 125.3 0.7 2.1e-36 125.3 0.7 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PVD32741.1 - 2.3e-19 70.1 0.0 2.3e-18 66.8 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_tran_WecB PF03808.13 PVD32741.1 - 0.086 12.8 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Methyltransf_4 PF02390.17 PVD32741.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF3764 PF12594.8 PVD32741.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) RPA_interact_C PF14768.6 PVD32742.1 - 1.5e-19 70.3 5.3 3.1e-19 69.3 5.3 1.5 1 0 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 PVD32742.1 - 4e-11 42.3 2.3 7.7e-11 41.4 2.3 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_M PF14767.6 PVD32742.1 - 5.1e-06 27.0 7.3 1.2e-05 25.7 7.3 1.7 1 0 0 1 1 1 1 Replication protein A interacting middle DNA_RNApol_7kD PF03604.13 PVD32742.1 - 0.14 11.8 4.0 0.2 11.3 1.5 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit P66_CC PF16563.5 PVD32742.1 - 0.58 9.8 5.4 4 7.1 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 PTR2 PF00854.21 PVD32743.1 - 7e-85 285.2 10.3 1.6e-84 284.1 9.0 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 PVD32743.1 - 3.2e-06 26.3 30.4 3.2e-06 26.3 30.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Fringe PF02434.16 PVD32744.1 - 5.8e-15 55.4 0.1 1.9e-13 50.4 0.1 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD32744.1 - 1e-08 35.2 0.6 0.00012 22.0 0.3 2.2 1 1 1 2 2 2 2 Galactosyltransferase Glyco_transf_22 PF03901.17 PVD32745.1 - 4.4e-27 95.4 7.7 3.4e-26 92.5 7.7 2.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family TPR_19 PF14559.6 PVD32745.1 - 0.049 14.1 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3165 PF11364.8 PVD32745.1 - 0.13 12.7 0.2 0.4 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) TPR_21 PF09976.9 PVD32745.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain RRM_1 PF00076.22 PVD32746.1 - 4.7e-16 58.4 0.0 1.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 PVD32746.1 - 1.2e-07 31.9 11.9 1 9.9 1.1 8.1 4 2 4 9 9 9 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PVD32746.1 - 3.4e-07 30.0 0.7 7.8e-07 28.9 0.7 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 PVD32746.1 - 1.8e-06 27.5 13.9 2.4 8.5 0.0 9.0 10 0 0 10 10 10 2 Leucine Rich repeat LRR_8 PF13855.6 PVD32746.1 - 4.8e-06 26.2 7.5 0.65 9.8 0.0 5.2 5 1 0 5 5 5 3 Leucine rich repeat F-box PF00646.33 PVD32746.1 - 8.2e-05 22.4 2.2 9.8e-05 22.1 0.2 2.2 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 PVD32746.1 - 0.00011 21.8 0.3 0.98 9.1 0.0 4.6 4 1 2 6 6 6 1 Protein of unknown function (DUF1699) MitMem_reg PF13012.6 PVD32746.1 - 0.12 12.8 0.1 30 5.1 0.0 2.7 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function RRM_3 PF08777.11 PVD32746.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif CBF PF03914.17 PVD32747.1 - 7.9e-29 100.9 5.4 1.2e-28 100.3 1.9 2.5 2 0 0 2 2 2 1 CBF/Mak21 family adh_short PF00106.25 PVD32747.1 - 9.4e-15 54.6 0.1 1.6e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD32747.1 - 2.9e-13 49.9 0.0 7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD32747.1 - 3e-08 33.8 0.0 7.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD32747.1 - 6.2e-06 25.9 0.1 0.00038 20.0 0.1 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD32747.1 - 4.5e-05 23.0 0.1 0.00013 21.5 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 PVD32747.1 - 9.8e-05 22.4 0.5 0.00072 19.6 0.4 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PVD32747.1 - 0.0011 19.4 0.3 0.003 18.0 0.3 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 PVD32747.1 - 0.0023 18.2 0.6 0.015 15.6 0.3 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 PVD32747.1 - 0.0034 17.9 0.1 0.0093 16.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 PVD32747.1 - 0.059 13.4 0.9 0.1 12.7 0.3 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.15 PVD32747.1 - 0.061 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 PVD32747.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.8 PVD32747.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain YjeF_N PF03853.15 PVD32747.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus SNF2_N PF00176.23 PVD32748.1 - 2.8e-67 226.9 5.3 6.3e-67 225.8 5.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain EP400_N PF15790.5 PVD32748.1 - 1.5e-28 99.9 19.1 1.5e-28 99.9 19.1 7.1 3 3 3 7 7 7 1 E1A-binding protein p400, N-terminal HSA PF07529.13 PVD32748.1 - 3e-21 75.5 8.1 3e-21 75.5 8.1 4.8 4 1 1 5 5 5 2 HSA Helicase_C PF00271.31 PVD32748.1 - 8.8e-20 71.1 0.1 3.3e-19 69.3 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GSHPx PF00255.19 PVD32748.1 - 2.3e-06 27.1 0.0 7.5e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione peroxidase Myb_DNA-binding PF00249.31 PVD32748.1 - 0.008 16.4 0.3 0.042 14.0 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain EDR1 PF14381.6 PVD32748.1 - 0.068 12.9 0.2 0.2 11.4 0.2 1.8 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Tfb4 PF03850.14 PVD32749.1 - 4.7e-76 255.9 0.8 2.2e-51 175.0 0.2 2.2 1 1 1 2 2 2 2 Transcription factor Tfb4 BCAS3 PF12490.8 PVD32749.1 - 1.6e-30 106.4 0.0 2.7e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 PVD32749.1 - 0.52 11.3 5.1 4.2 8.4 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3682 PF12446.8 PVD32751.1 - 0.0036 17.8 19.9 0.0038 17.7 19.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) Afaf PF15339.6 PVD32751.1 - 0.0047 16.7 1.6 0.0051 16.5 1.6 1.1 1 0 0 1 1 1 1 Acrosome formation-associated factor CPSF100_C PF13299.6 PVD32751.1 - 0.0089 16.2 1.9 0.0089 16.2 1.9 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 PVD32751.1 - 0.012 14.7 9.9 0.011 14.7 9.9 1.0 1 0 0 1 1 1 0 Paf1 FAM76 PF16046.5 PVD32751.1 - 0.014 14.8 4.9 0.015 14.6 4.9 1.0 1 0 0 1 1 1 0 FAM76 protein FAM176 PF14851.6 PVD32751.1 - 0.016 14.9 7.1 0.017 14.8 7.1 1.1 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 PVD32751.1 - 0.021 14.1 1.5 0.021 14.1 1.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 PVD32751.1 - 0.021 14.2 7.9 0.021 14.2 7.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 PVD32751.1 - 0.03 14.1 2.7 0.035 13.8 2.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SelP_N PF04592.14 PVD32751.1 - 0.044 13.2 16.8 0.052 13.0 16.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4746 PF15928.5 PVD32751.1 - 0.047 13.1 7.7 0.05 13.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 PVD32751.1 - 0.053 13.3 3.6 0.057 13.2 3.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EIIBC-GUT_N PF03612.14 PVD32751.1 - 0.094 12.4 4.2 0.098 12.4 4.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus E7 PF00527.18 PVD32751.1 - 0.1 12.8 7.9 0.13 12.4 7.9 1.2 1 0 0 1 1 1 0 E7 protein, Early protein Connexin PF00029.19 PVD32751.1 - 0.13 12.0 5.6 0.14 11.9 5.6 1.1 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 PVD32751.1 - 0.16 9.8 6.3 0.17 9.8 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ctr PF04145.15 PVD32751.1 - 0.16 12.5 2.7 0.19 12.4 2.7 1.0 1 0 0 1 1 1 0 Ctr copper transporter family Folate_carrier PF01770.18 PVD32751.1 - 0.26 10.0 3.6 0.26 10.0 3.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier G0-G1_switch_2 PF15103.6 PVD32751.1 - 0.44 11.0 5.3 0.54 10.7 5.3 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Serinc PF03348.15 PVD32751.1 - 0.46 9.3 3.6 0.54 9.1 3.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) P5-ATPase PF12409.8 PVD32751.1 - 0.51 10.4 3.3 0.59 10.2 3.3 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter Zip PF02535.22 PVD32751.1 - 0.55 9.4 8.8 0.59 9.3 8.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter PigN PF04987.14 PVD32751.1 - 0.66 8.8 3.1 0.61 8.9 3.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) RPA43_OB PF17875.1 PVD32751.1 - 0.72 10.5 8.0 0.81 10.3 8.0 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CPSF73-100_C PF11718.8 PVD32751.1 - 0.88 9.1 8.0 1 8.9 8.0 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Spt20 PF12090.8 PVD32751.1 - 0.9 9.1 13.6 1.1 8.8 13.6 1.1 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.6 PVD32751.1 - 1.1 9.6 4.8 1.3 9.4 4.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 PVD32751.1 - 1.2 7.8 8.4 1.3 7.8 8.4 1.0 1 0 0 1 1 1 0 Presenilin Ferlin_C PF16165.5 PVD32751.1 - 1.2 9.0 4.2 1.5 8.8 4.2 1.1 1 0 0 1 1 1 0 Ferlin C-terminus CLN3 PF02487.17 PVD32751.1 - 1.3 8.0 4.4 1.3 8.0 4.4 1.0 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 PVD32751.1 - 2 8.1 4.6 2.2 8.0 4.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 PVD32751.1 - 2.1 8.3 4.0 2.2 8.3 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIM3 PF17096.5 PVD32751.1 - 5.7 7.9 8.3 8.5 7.4 8.3 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Nucleoside_tran PF01733.18 PVD32751.1 - 5.9 6.2 5.7 7.1 5.9 5.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter Roughex PF06020.11 PVD32751.1 - 9.8 5.2 13.5 12 4.9 13.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein T-box PF00907.22 PVD32752.1 - 5e-08 33.4 0.2 9.1e-08 32.6 0.1 1.5 2 0 0 2 2 2 1 T-box T-box PF00907.22 PVD32753.1 - 2.8e-68 229.8 0.4 4.1e-68 229.3 0.4 1.2 1 0 0 1 1 1 1 T-box T-box PF00907.22 PVD32754.1 - 6.4e-35 121.1 0.0 8.1e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 T-box YkuD PF03734.14 PVD32754.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain T-box PF00907.22 PVD32755.1 - 6e-26 91.8 0.9 8.7e-26 91.3 0.9 1.2 1 0 0 1 1 1 1 T-box SDA1 PF05285.12 PVD32755.1 - 0.96 8.8 6.1 1.3 8.4 6.1 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 PVD32760.1 - 3.2 6.9 4.1 3.5 6.8 4.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter T-box PF00907.22 PVD32763.1 - 1e-84 283.4 0.3 1.4e-84 283.0 0.3 1.2 1 0 0 1 1 1 1 T-box G_glu_transpept PF01019.21 PVD32768.1 - 7.7e-154 513.2 0.0 1.5e-112 377.0 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 PVD32769.1 - 3.2e-120 402.3 5.5 1.2e-97 327.9 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 PVD32770.1 - 6.5e-128 427.7 0.2 6.5e-127 424.4 0.2 2.1 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Ion_trans PF00520.31 PVD32771.1 - 2e-06 27.3 7.7 2.6e-06 26.8 7.7 1.2 1 0 0 1 1 1 1 Ion transport protein DUF4200 PF13863.6 PVD32771.1 - 0.0044 17.4 1.0 0.0095 16.3 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) VGPC1_C PF16799.5 PVD32771.1 - 0.011 15.7 0.3 0.03 14.3 0.3 1.8 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 RTX PF02382.15 PVD32771.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein CRPA PF05745.11 PVD32771.1 - 1.7 8.6 7.1 1.6 8.7 5.7 1.7 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Phosphonate-bd PF12974.7 PVD32772.1 - 9.7e-29 100.7 0.0 1.6e-28 100.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein EMG1 PF03587.14 PVD32774.1 - 3.5e-85 284.6 0.1 4.3e-85 284.3 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1264 PF06884.11 PVD32774.1 - 0.15 11.6 0.1 0.5 9.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1264) SpoU_methylase PF00588.19 PVD32775.1 - 7.7e-25 87.7 0.0 4.6e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 PVD32775.1 - 7.8e-05 22.9 0.1 0.00087 19.5 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Glyoxalase PF00903.25 PVD32776.1 - 6.9e-06 26.3 0.0 0.00011 22.4 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 PVD32776.1 - 0.00024 21.2 0.2 0.082 13.0 0.0 3.2 3 1 1 4 4 4 2 CppA N-terminal Glyoxalase_6 PF18029.1 PVD32776.1 - 0.028 15.2 0.0 2 9.2 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase-like domain NCBP3 PF10309.9 PVD32777.1 - 1e-18 66.9 0.1 1.8e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 PVD32777.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain Prp19 PF08606.11 PVD32778.1 - 3e-32 110.4 2.5 7e-32 109.2 2.5 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 PVD32778.1 - 6.6e-29 99.5 1.3 6.9e-06 26.7 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32778.1 - 4e-11 43.1 0.1 0.17 12.2 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD32778.1 - 5e-05 22.4 0.3 1.1 8.2 0.0 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD32778.1 - 0.00016 21.6 0.2 0.11 12.3 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 PVD32778.1 - 0.00021 21.4 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Cytochrom_D1 PF02239.16 PVD32778.1 - 0.0043 15.7 0.5 0.019 13.5 0.1 2.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain zf-Nse PF11789.8 PVD32778.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.8 PVD32778.1 - 0.034 12.8 0.0 4 5.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HPS3_N PF14761.6 PVD32778.1 - 0.038 13.5 0.0 3.2 7.2 0.0 2.7 2 1 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Ank PF00023.30 PVD32779.1 - 7.3e-06 26.2 5.3 0.00045 20.6 0.1 3.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PVD32779.1 - 2.3e-05 24.6 0.2 0.00044 20.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD32779.1 - 7.7e-05 23.0 0.9 0.00019 21.7 0.9 1.6 1 0 0 1 1 1 1 SOCS box Ank_3 PF13606.6 PVD32779.1 - 0.0008 19.7 0.1 0.45 11.2 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PVD32779.1 - 0.011 16.4 0.0 0.15 12.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD32779.1 - 0.023 15.2 0.1 5.6 7.7 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Il2rg PF15874.5 PVD32780.1 - 9.8e-29 99.5 0.0 1.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Chromadorea_ALT PF05535.12 PVD32780.1 - 0.019 15.2 0.2 0.03 14.5 0.2 1.3 1 0 0 1 1 1 0 Chromadorea ALT protein Trypan_PARP PF05887.11 PVD32781.1 - 9.5 6.2 7.2 15 5.6 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) His_Phos_1 PF00300.22 PVD32782.1 - 7.2e-14 51.9 0.0 1.7e-10 40.9 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.6 PVD32782.1 - 2e-10 40.4 0.3 4.1e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain UBA PF00627.31 PVD32782.1 - 3.1e-08 33.4 0.0 7.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SH3_1 PF00018.28 PVD32782.1 - 0.00024 20.6 0.1 0.00051 19.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.16 PVD32782.1 - 0.0024 18.0 0.2 0.7 10.1 0.0 2.5 2 0 0 2 2 2 2 LigT like Phosphoesterase CPDase PF07823.11 PVD32782.1 - 0.049 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 PVD32782.1 - 0.1 12.5 1.0 1.8 8.4 1.0 2.3 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Laminin_II PF06009.12 PVD32784.1 - 0.017 15.2 1.3 0.036 14.1 1.3 1.5 1 0 0 1 1 1 0 Laminin Domain II Musclin PF11037.8 PVD32784.1 - 0.038 13.9 1.5 0.22 11.4 0.2 2.2 2 0 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle DUF1664 PF07889.12 PVD32784.1 - 0.045 13.8 0.9 0.12 12.4 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PVD32784.1 - 0.15 12.5 0.8 1.9 9.0 0.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fibrinogen_C PF00147.18 PVD32785.1 - 1.3e-66 224.5 12.7 1.7e-66 224.2 12.7 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Cytochrome_C554 PF13435.6 PVD32786.1 - 0.59 11.1 0.2 0.59 11.1 0.2 3.0 3 0 0 3 3 3 0 Cytochrome c554 and c-prime Peptidase_M10 PF00413.24 PVD32787.1 - 6.2e-54 182.1 0.4 1.1e-53 181.3 0.4 1.4 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 PVD32787.1 - 2.8e-11 43.5 0.1 6e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 PVD32787.1 - 0.00018 21.4 0.1 0.00018 21.4 0.1 2.7 3 0 0 3 3 3 1 Hemopexin Reprolysin_3 PF13582.6 PVD32787.1 - 0.001 19.6 0.1 0.0037 17.8 0.1 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 PVD32787.1 - 0.0066 16.1 0.0 0.86 9.2 0.0 2.3 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 PVD32787.1 - 0.028 14.6 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 PVD32787.1 - 0.084 11.8 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Tox-URI2 PF15653.6 PVD32787.1 - 0.22 11.8 0.0 0.63 10.3 0.0 1.7 2 0 0 2 2 2 0 URI fold toxin 2 Peptidase_M10 PF00413.24 PVD32788.1 - 3.7e-56 189.3 0.4 5.9e-56 188.7 0.4 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 PVD32788.1 - 3.3e-10 40.0 0.1 6.2e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 PVD32788.1 - 1.1e-07 31.7 1.4 0.0066 16.4 0.0 3.3 4 0 0 4 4 4 2 Hemopexin Reprolysin_3 PF13582.6 PVD32788.1 - 1.5e-05 25.5 0.2 5.2e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD32788.1 - 0.00013 22.2 0.1 0.00026 21.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 PVD32788.1 - 0.0023 17.6 0.1 0.87 9.2 0.0 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) RICTOR_phospho PF14665.6 PVD32788.1 - 0.018 15.4 0.2 0.038 14.3 0.2 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Peptidase_M66 PF10462.9 PVD32788.1 - 0.038 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 PVD32788.1 - 0.057 12.6 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 PVD32788.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 CAP_GLY PF01302.25 PVD32789.1 - 1.6e-44 149.7 2.6 4.1e-22 78.0 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 PVD32789.1 - 4.4e-07 29.6 18.4 4.7e-06 26.3 7.2 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle GAD PF02938.14 PVD32789.1 - 0.054 13.7 0.4 0.38 11.0 0.4 2.6 1 0 0 1 1 1 0 GAD domain RTBV_P46 PF06216.11 PVD32789.1 - 2.9 6.7 14.3 3.3 6.5 2.4 2.9 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein TM2 PF05154.16 PVD32791.1 - 3e-45 152.3 54.0 1.3e-14 54.3 5.7 4.5 4 0 0 4 4 4 4 TM2 domain Peptidase_M14 PF00246.24 PVD32791.1 - 0.037 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Zinc carboxypeptidase TMEM144 PF07857.12 PVD32792.1 - 0.058 12.3 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Dickkopf_N PF04706.12 PVD32792.1 - 1.3 9.5 20.2 3.9 8.0 20.2 1.8 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region VWA PF00092.28 PVD32793.1 - 6.9e-40 137.1 1.3 8.6e-37 127.1 0.3 2.7 2 1 1 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD32793.1 - 3.5e-14 53.4 0.1 6e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD32793.1 - 5e-07 29.8 0.0 1.9e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Copine PF07002.16 PVD32793.1 - 0.00037 20.0 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 2 Copine PALP PF00291.25 PVD32793.1 - 0.021 14.3 0.0 0.052 13.0 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DivIC PF04977.15 PVD32794.1 - 0.039 13.7 1.9 0.056 13.2 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 PVD32796.1 - 9.7e-83 272.8 28.2 2.6e-14 53.5 4.5 10.4 3 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD32796.1 - 4.3e-66 218.5 27.4 5.6e-11 42.7 0.3 15.4 5 4 9 16 16 16 15 Ankyrin repeats (many copies) Ank PF00023.30 PVD32796.1 - 2.5e-61 201.6 44.2 1.6e-06 28.3 0.1 19.7 20 0 0 20 20 20 14 Ankyrin repeat Ank_3 PF13606.6 PVD32796.1 - 3.3e-59 189.9 34.6 3.2e-05 24.0 0.0 19.4 22 0 0 22 22 22 14 Ankyrin repeat Ank_5 PF13857.6 PVD32796.1 - 3.4e-57 189.8 31.3 8e-09 35.6 0.1 14.8 10 5 4 14 14 14 12 Ankyrin repeats (many copies) BTB PF00651.31 PVD32796.1 - 0.00027 21.1 0.1 0.0025 18.0 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD32796.1 - 0.0024 17.9 0.7 0.023 14.8 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch TLD PF07534.16 PVD32798.1 - 8e-09 35.8 0.1 3.3e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 TLD 2OG-FeII_Oxy_2 PF13532.6 PVD32799.1 - 9.5e-07 29.2 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PVD32799.1 - 0.015 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.22 PVD32800.1 - 2.9e-82 276.6 0.0 3.9e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Transglut_core PF01841.19 PVD32803.1 - 0.0002 21.8 0.0 0.00045 20.6 0.0 1.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily EVC2_like PF12297.8 PVD32803.1 - 0.081 11.6 3.3 0.13 11.0 3.3 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CTV_P23 PF04808.12 PVD32803.1 - 0.18 11.3 0.1 0.39 10.2 0.1 1.6 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein LIM PF00412.22 PVD32804.1 - 8e-10 38.8 3.4 1.4e-09 38.1 3.4 1.4 1 0 0 1 1 1 1 LIM domain Mod_r PF07200.13 PVD32805.1 - 2e-32 112.3 14.5 2.4e-32 112.1 14.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DASH_Dam1 PF08653.10 PVD32805.1 - 2.3 8.1 4.9 5.3 6.9 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Neuromodulin PF06614.11 PVD32806.1 - 0.029 14.6 1.1 0.029 14.6 1.1 1.6 2 0 0 2 2 2 0 Neuromodulin Collagen PF01391.18 PVD32806.1 - 0.05 13.4 6.1 0.15 11.8 6.1 1.9 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Guanylate_cyc PF00211.20 PVD32808.1 - 8.8e-60 201.5 0.0 1.7e-59 200.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD32808.1 - 2.3e-36 125.4 0.0 5.4e-36 124.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD32808.1 - 3.5e-27 95.4 0.0 6.3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 PVD32808.1 - 1.1e-06 28.3 0.2 1.9e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated ANF_receptor PF01094.28 PVD32808.1 - 2.2e-06 27.0 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SHR3_chaperone PF08229.11 PVD32808.1 - 0.044 12.7 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 Anoctamin PF04547.12 PVD32808.1 - 0.061 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel BT1 PF03092.16 PVD32808.1 - 0.09 11.0 0.7 0.19 9.9 0.0 1.7 2 0 0 2 2 2 0 BT1 family DUF2681 PF10883.8 PVD32808.1 - 0.14 12.6 0.2 0.36 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ANF_receptor PF01094.28 PVD32809.1 - 4.1e-06 26.1 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DHFR_1 PF00186.19 PVD32810.1 - 4.5e-15 55.7 0.0 5.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase His_Phos_2 PF00328.22 PVD32811.1 - 6.3e-100 335.2 0.1 1.2e-99 334.3 0.1 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 PVD32811.1 - 4.2e-39 132.6 0.3 8e-39 131.7 0.3 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 PVD32811.1 - 0.0015 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 PVD32811.1 - 0.015 15.0 0.2 13 5.4 0.0 3.5 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) RVT_1 PF00078.27 PVD32812.1 - 0.039 13.5 0.1 0.043 13.3 0.1 1.2 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.27 PVD32815.1 - 5.6e-20 71.3 41.2 3.5e-08 33.6 8.8 3.7 3 0 0 3 3 3 3 EGF-like domain CBM_14 PF01607.24 PVD32815.1 - 3e-10 40.1 4.8 3e-10 40.1 4.8 3.8 3 1 0 3 3 3 2 Chitin binding Peritrophin-A domain hEGF PF12661.7 PVD32815.1 - 3e-09 37.2 34.6 0.0018 18.8 6.2 4.2 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 PVD32815.1 - 4.3e-08 33.4 50.0 0.0077 16.6 12.5 3.8 3 0 0 3 3 3 3 EGF-like domain Antimicrobial10 PF08105.11 PVD32815.1 - 0.43 10.7 5.2 7.1 6.8 0.3 2.8 2 0 0 2 2 2 0 Metchnikowin family PagP PF07017.11 PVD32815.1 - 0.48 9.8 3.7 0.71 9.3 0.2 2.7 1 1 2 3 3 3 0 Antimicrobial peptide resistance and lipid A acylation protein PagP NAGLU_N PF12971.7 PVD32816.1 - 0.038 13.8 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF4556 PF15094.6 PVD32816.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Band_7 PF01145.25 PVD32817.1 - 4.1e-22 79.0 0.0 4.1e-22 79.0 0.0 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 PVD32817.1 - 1.6e-08 34.8 1.7 1.6e-08 34.8 1.7 3.1 3 1 0 3 3 3 2 Flotillin Band_7_1 PF13421.6 PVD32817.1 - 0.004 16.9 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Ntox15 PF15604.6 PVD32817.1 - 1.1 9.3 10.1 0.42 10.7 5.9 2.2 1 1 1 2 2 2 0 Novel toxin 15 Metallophos PF00149.28 PVD32818.1 - 4.7e-39 135.0 0.1 6.4e-39 134.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD32818.1 - 0.00045 20.6 1.5 0.00073 19.9 0.5 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 PVD32818.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPH PF13868.6 PVD32819.1 - 5.1e-28 97.6 148.4 5.1e-28 97.6 148.4 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain PilJ_C PF18223.1 PVD32819.1 - 7.7 7.1 7.8 1.1 9.8 0.1 3.4 4 1 1 5 5 5 0 Pili PilJ C-terminal domain GLTP PF08718.11 PVD32820.1 - 1.4e-34 119.6 0.0 1.7e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Transglut_prok PF09017.10 PVD32820.1 - 0.04 13.2 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase L_HMGIC_fpl PF10242.9 PVD32821.1 - 0.00035 20.8 0.8 0.00044 20.5 0.8 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein L_HMGIC_fpl PF10242.9 PVD32822.1 - 5e-15 56.2 1.5 6.9e-15 55.7 1.5 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 PVD32822.1 - 0.21 11.3 3.3 0.39 10.4 3.2 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Gram_pos_anchor PF00746.21 PVD32822.1 - 0.37 10.8 0.8 0.85 9.6 0.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif L_HMGIC_fpl PF10242.9 PVD32823.1 - 2.5e-11 44.1 5.6 3.9e-11 43.5 5.6 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF3311 PF11755.8 PVD32823.1 - 0.52 10.3 8.7 0.51 10.3 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF4769 PF15992.5 PVD32823.1 - 2.3 8.0 4.5 1.2 8.9 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) PT PF04886.12 PVD32824.1 - 0.0014 18.1 88.8 1.8e+04 -36.5 88.8 4.5 1 1 0 1 1 0 0 PT repeat Presenilin PF01080.17 PVD32824.1 - 0.79 8.4 8.5 0.88 8.3 8.5 1.1 1 0 0 1 1 1 0 Presenilin ASD2 PF08687.11 PVD32824.1 - 1.5 8.4 4.9 1.7 8.1 4.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF4699 PF15770.5 PVD32824.1 - 1.5 8.5 14.9 1.8 8.3 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) SPX PF03105.19 PVD32824.1 - 1.8 8.4 15.1 1.9 8.3 15.1 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 PVD32824.1 - 2 7.0 17.6 2.2 6.9 17.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 PVD32824.1 - 2.1 8.3 22.8 2.4 8.1 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peroxin-3 PF04882.12 PVD32824.1 - 3.1 6.7 10.2 3.4 6.5 10.2 1.0 1 0 0 1 1 1 0 Peroxin-3 DUF4678 PF15727.5 PVD32824.1 - 4.3 6.5 11.0 4.6 6.4 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) RR_TM4-6 PF06459.12 PVD32824.1 - 5.1 6.8 9.1 5.6 6.7 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 PVD32824.1 - 8.1 5.3 8.3 8.9 5.2 8.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Ion_trans_2 PF07885.16 PVD32827.1 - 0.0027 17.6 6.1 0.0031 17.4 0.6 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans_2 PF07885.16 PVD32828.1 - 1.4e-25 89.1 15.7 6.2e-17 61.3 5.5 2.3 2 0 0 2 2 2 2 Ion channel Acyl_transf_3 PF01757.22 PVD32828.1 - 0.01 15.0 2.0 0.019 14.0 2.0 1.3 1 0 0 1 1 1 0 Acyltransferase family BCD PF15461.6 PVD32828.1 - 0.016 14.7 1.9 0.027 14.0 1.9 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Reo_sigmaC_M PF17750.1 PVD32828.1 - 0.042 13.7 0.5 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein triple beta spiral Pox_A9 PF04835.12 PVD32828.1 - 0.82 9.9 2.1 7.2 6.8 0.2 2.4 2 0 0 2 2 2 0 A9 protein conserved region Ion_trans PF00520.31 PVD32828.1 - 5.2 6.2 8.8 1.7 7.8 5.1 1.8 2 0 0 2 2 2 0 Ion transport protein TFIIA PF03153.13 PVD32828.1 - 7.7 6.4 8.9 13 5.6 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBM39 PF15886.5 PVD32830.1 - 4e-18 65.3 0.0 1.3e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain (family 32) AAT PF03417.16 PVD32831.1 - 5.2e-22 78.6 0.0 5.2e-22 78.6 0.0 5.6 3 2 1 4 4 4 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AAT PF03417.16 PVD32832.1 - 2.9e-22 79.5 0.0 5.4e-22 78.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AAT PF03417.16 PVD32833.1 - 2.7e-18 66.5 0.0 4.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase IU_nuc_hydro PF01156.19 PVD32834.1 - 4.4e-67 226.8 0.1 8.9e-67 225.8 0.1 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Integrase_H2C2 PF17921.1 PVD32834.1 - 3.9e-05 23.7 2.6 4.9e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-C2H2_jaz PF12171.8 PVD32834.1 - 0.00076 19.7 3.7 0.00076 19.7 3.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD32834.1 - 0.015 16.1 3.5 0.015 16.1 3.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD32834.1 - 0.017 15.6 4.8 0.017 15.6 4.8 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 PVD32834.1 - 0.46 11.0 8.1 0.11 13.0 2.4 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ColG_sub PF18496.1 PVD32836.1 - 0.17 12.1 3.9 0.83 9.8 0.3 3.0 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain AAA_6 PF12774.7 PVD32838.1 - 1e-155 517.7 3.7 1.8e-155 516.9 0.0 3.3 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD32838.1 - 8.2e-131 436.8 4.8 8.2e-131 436.8 4.8 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 PVD32838.1 - 1.8e-126 423.1 18.1 1.8e-126 423.1 18.1 3.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 PVD32838.1 - 3.2e-95 318.4 0.0 9.3e-95 316.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PVD32838.1 - 4.6e-83 279.0 0.0 2.1e-82 276.8 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD32838.1 - 1.5e-82 276.0 1.1 1e-81 273.3 0.8 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD32838.1 - 7e-74 247.3 3.2 4.8e-69 231.5 0.1 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD32838.1 - 1.6e-56 190.6 0.1 5.3e-56 188.9 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD32838.1 - 2.3e-28 98.7 0.0 1.6e-27 95.9 0.1 2.6 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD32838.1 - 2.4e-22 79.4 12.8 1.6e-18 66.9 0.2 3.4 3 0 0 3 3 3 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PVD32838.1 - 1.2e-20 73.9 1.1 2.7e-19 69.5 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD32838.1 - 2.1e-18 66.7 0.0 3.4e-05 23.9 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD32838.1 - 3.1e-17 62.6 0.1 2.3e-16 59.8 0.1 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PVD32838.1 - 2.9e-09 37.3 1.2 0.023 15.0 0.0 5.0 4 1 1 5 5 4 2 AAA domain AAA_16 PF13191.6 PVD32838.1 - 7.9e-07 29.6 0.1 0.84 10.0 0.0 5.7 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 PVD32838.1 - 3.2e-06 27.6 0.2 0.52 10.7 0.0 4.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 PVD32838.1 - 0.0021 17.2 0.1 0.73 8.8 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PVD32838.1 - 0.0028 17.6 0.1 0.047 13.6 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_10 PF12846.7 PVD32838.1 - 0.0041 16.1 0.0 0.016 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.22 PVD32838.1 - 0.0048 17.3 0.2 3.3 8.1 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 PVD32838.1 - 0.0065 16.2 3.9 7.2 6.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 PVD32838.1 - 0.0094 16.5 1.8 2.2 8.8 0.1 3.6 3 0 0 3 3 2 1 ABC transporter AAA_19 PF13245.6 PVD32838.1 - 0.036 14.4 5.3 6.1 7.2 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 PVD32838.1 - 0.073 13.6 0.2 1.8 9.2 0.0 3.5 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 PVD32838.1 - 0.11 11.9 0.0 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.16 PVD32838.1 - 0.13 11.7 0.4 3.2 7.1 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein AAA_33 PF13671.6 PVD32838.1 - 0.14 12.3 0.1 51 4.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain CENP-B_dimeris PF09026.10 PVD32838.1 - 2.8 8.4 7.8 5.9 7.3 6.9 2.0 2 0 0 2 2 1 0 Centromere protein B dimerisation domain FPP PF05911.11 PVD32838.1 - 3.7 5.6 20.2 1.3 7.1 3.1 3.0 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil TORC_N PF12884.7 PVD32838.1 - 5.2 7.9 5.6 4.7 8.1 2.3 2.5 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus DHC_N1 PF08385.12 PVD32839.1 - 1.2e-160 535.8 6.2 1.2e-160 535.8 6.2 3.6 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PVD32839.1 - 1.5e-144 481.0 0.0 7.2e-144 478.7 0.0 2.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD32839.1 - 1.2e-134 449.4 11.4 1.2e-134 449.4 11.4 4.7 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD32839.1 - 2.9e-100 334.9 0.0 6.9e-100 333.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PVD32839.1 - 1e-88 297.5 0.0 1e-88 297.5 0.0 4.2 6 0 0 6 6 6 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD32839.1 - 2e-88 295.2 2.4 6.4e-86 287.0 1.3 3.2 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD32839.1 - 8.1e-62 207.9 0.2 8.2e-59 198.2 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD32839.1 - 4.3e-57 192.5 0.1 1.3e-56 191.0 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PVD32839.1 - 1.1e-54 185.8 12.6 2.3e-54 184.7 12.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD32839.1 - 1.6e-44 150.8 0.2 1.9e-43 147.4 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD32839.1 - 1.1e-20 74.1 0.0 7.2e-20 71.4 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD32839.1 - 9.4e-19 67.8 0.6 0.0022 18.0 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD32839.1 - 3.5e-18 65.7 0.4 3.7e-17 62.4 0.1 3.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 PVD32839.1 - 3.5e-06 27.3 7.1 0.077 13.3 0.0 5.9 6 0 0 6 6 4 2 AAA domain AAA PF00004.29 PVD32839.1 - 5.9e-05 23.5 1.2 1.6 9.2 0.0 5.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PVD32839.1 - 0.00064 20.3 0.0 0.23 12.0 0.0 3.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD32839.1 - 0.025 15.0 7.2 10 6.5 0.0 5.7 6 0 0 6 6 4 0 AAA ATPase domain Plasmid_RAQPRD PF09686.10 PVD32839.1 - 0.099 12.9 2.5 3 8.1 0.0 4.0 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Fungal_TACC PF12709.7 PVD32839.1 - 0.14 12.6 5.1 2.2 8.8 5.1 3.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF948 PF06103.11 PVD32839.1 - 0.23 11.7 9.9 44 4.4 0.1 7.1 8 0 0 8 8 6 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 PVD32839.1 - 0.77 9.6 11.0 1.9 8.3 1.0 5.0 3 0 0 3 3 2 0 Spindle and kinetochore-associated protein 2 LPP PF04728.13 PVD32839.1 - 0.79 10.2 4.1 2.2 8.8 1.3 3.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 PVD32839.1 - 1.6 9.2 5.3 31 5.0 0.7 5.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HBM PF16591.5 PVD32839.1 - 2.1 7.7 14.1 0.25 10.7 0.6 5.1 6 0 0 6 6 6 0 Helical bimodular sensor domain Cofilin_ADF PF00241.20 PVD32840.1 - 2.6e-25 88.5 0.3 3e-25 88.4 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF5625 PF18539.1 PVD32840.1 - 0.022 15.0 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5625) TPR_12 PF13424.6 PVD32841.1 - 2.7e-26 91.6 20.2 4.4e-14 52.5 1.3 5.9 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 PVD32841.1 - 1.6e-24 85.0 4.6 3.9e-09 36.1 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD32841.1 - 3.6e-08 32.9 9.6 2.1e-05 24.1 0.2 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD32841.1 - 4.5e-05 23.2 5.3 0.0073 16.3 0.0 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD32841.1 - 0.00026 21.0 13.7 0.01 16.0 0.3 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD32841.1 - 0.0003 20.7 9.7 1.2 9.4 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD32841.1 - 0.00065 19.2 7.3 0.0033 16.9 0.9 3.7 2 1 1 4 4 4 1 MalT-like TPR region TPR_14 PF13428.6 PVD32841.1 - 0.00097 19.8 0.5 12 7.0 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD32841.1 - 0.0071 16.7 0.9 11 6.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD32841.1 - 0.017 15.1 4.7 1.9 8.5 0.3 3.3 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 SCAN PF02023.17 PVD32842.1 - 9.2e-11 41.4 0.1 1.3e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 SCAN domain Asp_protease_2 PF13650.6 PVD32842.1 - 0.0034 18.0 0.0 0.0066 17.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease vATP-synt_E PF01991.18 PVD32842.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit gag-asp_proteas PF13975.6 PVD32842.1 - 0.08 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 PVD32842.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease MFS_1 PF07690.16 PVD32843.1 - 1.1e-19 70.6 6.6 9e-14 51.1 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD32843.1 - 0.00011 21.2 2.6 0.005 15.8 2.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter PT PF04886.12 PVD32843.1 - 0.022 14.3 3.6 0.04 13.4 3.6 1.4 1 0 0 1 1 1 0 PT repeat NERD PF08378.11 PVD32844.1 - 0.0012 19.3 0.2 0.0033 17.9 0.2 1.8 1 0 0 1 1 1 1 Nuclease-related domain AAA_16 PF13191.6 PVD32844.1 - 0.078 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain BCL_N PF04714.13 PVD32845.1 - 2.9e-28 97.7 8.4 2.9e-28 97.7 8.4 1.9 2 0 0 2 2 2 1 BCL7, N-terminal conserver region Qua1 PF16274.5 PVD32845.1 - 4.9 7.1 5.3 1.2 9.0 0.3 2.4 3 0 0 3 3 3 0 Qua1 domain GCM PF03615.15 PVD32846.1 - 0.0016 18.3 2.2 0.004 17.0 2.2 1.6 1 0 0 1 1 1 1 GCM motif protein VWA PF00092.28 PVD32848.1 - 1.5e-62 211.0 0.1 4.1e-40 137.9 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD32848.1 - 1.1e-18 67.8 0.4 2.2e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD32848.1 - 2.9e-06 27.3 0.1 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain ETF PF01012.21 PVD32848.1 - 0.13 12.2 0.0 1.2 9.0 0.0 2.3 3 0 0 3 3 3 0 Electron transfer flavoprotein domain WD40 PF00400.32 PVD32850.1 - 7.2e-19 67.8 3.8 0.00013 22.7 0.3 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SAD_SRA PF02182.17 PVD32850.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 SAD/SRA domain PD40 PF07676.12 PVD32850.1 - 0.11 12.5 1.2 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PMP22_Claudin PF00822.20 PVD32851.1 - 4.1e-07 30.0 16.9 5.9e-07 29.5 16.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD32851.1 - 1.3e-06 28.3 11.5 1.3e-06 28.3 11.5 3.0 1 1 2 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction DUF5316 PF17247.2 PVD32851.1 - 0.095 12.7 0.4 0.095 12.7 0.4 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5316) EF-hand_6 PF13405.6 PVD32852.1 - 4.2e-15 54.3 3.7 0.00015 21.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PVD32852.1 - 1.2e-13 49.9 3.7 0.00045 19.6 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PVD32852.1 - 3e-13 50.0 0.6 0.00091 19.6 0.2 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 PVD32852.1 - 2e-12 45.7 3.3 0.017 14.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PVD32852.1 - 7.8e-05 22.4 0.9 1.3 9.0 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD32852.1 - 0.0006 20.1 2.0 0.26 11.6 0.0 3.0 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD32852.1 - 0.00078 19.6 1.8 2.3 8.5 0.1 3.4 4 0 0 4 4 4 2 Dockerin type I domain Caleosin PF05042.13 PVD32852.1 - 0.013 15.4 3.3 4.1 7.3 0.6 3.7 3 1 0 3 3 3 0 Caleosin related protein EF-hand_6 PF13405.6 PVD32853.1 - 3.3e-29 98.3 29.0 9.3e-05 22.1 0.1 14.2 11 2 3 14 14 14 4 EF-hand domain EF-hand_7 PF13499.6 PVD32853.1 - 7.5e-26 90.4 9.6 9.7e-05 22.8 0.0 7.8 6 1 1 7 7 7 6 EF-hand domain pair EF-hand_1 PF00036.32 PVD32853.1 - 1.5e-24 83.6 32.5 0.0038 16.7 0.0 14.5 14 1 1 15 15 15 7 EF hand EF-hand_5 PF13202.6 PVD32853.1 - 2e-24 83.9 37.4 0.0007 19.0 0.1 13.6 14 0 0 14 14 14 5 EF hand Caleosin PF05042.13 PVD32853.1 - 6.8e-07 29.4 10.4 0.37 10.7 0.1 8.1 7 2 2 9 9 9 1 Caleosin related protein EF-hand_8 PF13833.6 PVD32853.1 - 1e-06 28.5 13.6 11 6.0 0.0 10.3 10 2 0 10 10 10 1 EF-hand domain pair Swi6_N PF18530.1 PVD32853.1 - 0.00038 20.6 0.3 11 6.2 0.0 4.0 3 1 0 3 3 3 2 Swi6 N-terminal domain SPARC_Ca_bdg PF10591.9 PVD32853.1 - 0.00044 20.6 8.0 20 5.5 0.1 6.2 4 3 1 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region Rho_N PF07498.12 PVD32853.1 - 0.0016 18.3 8.6 1.5 8.8 0.2 5.3 5 0 0 5 5 5 1 Rho termination factor, N-terminal domain DUF5411 PF17424.2 PVD32853.1 - 0.0068 16.4 0.3 15 5.5 0.0 4.5 5 0 0 5 5 5 0 Family of unknown function (DUF5411) DUF2418 PF10332.9 PVD32853.1 - 0.076 13.6 0.4 92 3.7 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) EF-hand_9 PF14658.6 PVD32853.1 - 0.086 13.2 0.0 1e+02 3.3 0.0 3.9 3 0 0 3 3 3 0 EF-hand domain SinI PF08671.10 PVD32853.1 - 0.15 11.9 1.2 21 5.0 0.2 3.3 2 0 0 2 2 2 0 Anti-repressor SinI DUF5400 PF17379.2 PVD32853.1 - 0.36 11.3 1.7 34 5.0 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5400) LPD18 PF18832.1 PVD32853.1 - 0.54 10.4 2.4 7.9 6.6 0.0 3.6 5 0 0 5 5 5 0 Large polyvalent protein-associated domain 18 EF-hand_5 PF13202.6 PVD32854.1 - 2.2e-10 39.5 1.2 0.002 17.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_1 PF00036.32 PVD32854.1 - 1.2e-09 37.0 1.1 0.046 13.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD32854.1 - 2.1e-07 30.3 2.5 0.015 15.2 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PVD32854.1 - 1.4e-06 28.7 0.1 0.32 11.5 0.1 3.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 PVD32854.1 - 4.6e-06 26.4 0.2 1.7 8.5 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair Nif11 PF07862.11 PVD32854.1 - 0.023 15.0 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Nif11 domain Aminotran_4 PF01063.19 PVD32854.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Amino-transferase class IV Sulfotransfer_1 PF00685.27 PVD32855.1 - 1.6e-86 290.1 8.9 1.1e-48 166.0 1.2 3.6 2 2 0 2 2 2 2 Sulfotransferase domain EF-hand_5 PF13202.6 PVD32855.1 - 1.1e-18 65.8 0.0 0.00092 18.6 0.0 5.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 PVD32855.1 - 3.3e-17 60.9 8.0 0.00024 20.8 0.0 7.1 7 0 0 7 7 6 3 EF-hand domain EF-hand_1 PF00036.32 PVD32855.1 - 1e-16 59.1 1.1 0.016 14.7 0.0 6.2 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 PVD32855.1 - 2.7e-15 56.5 0.0 1.2e-05 25.7 0.0 5.1 3 2 0 3 3 3 2 EF-hand domain pair Sulfotransfer_3 PF13469.6 PVD32855.1 - 1.9e-12 48.1 0.1 0.00011 22.6 0.0 4.4 4 1 0 5 5 5 2 Sulfotransferase family EF-hand_8 PF13833.6 PVD32855.1 - 1.6e-05 24.7 6.2 16 5.4 0.0 6.4 6 0 0 6 6 6 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD32855.1 - 0.00072 19.9 2.6 7.2 7.0 0.0 4.9 5 0 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD32855.1 - 0.019 15.1 1.4 19 5.6 0.1 3.7 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_10 PF14788.6 PVD32855.1 - 0.024 14.5 0.4 11 6.0 0.0 3.2 3 0 0 3 3 3 0 EF hand DUF2112 PF09885.9 PVD32855.1 - 0.072 13.1 0.7 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) EF-hand_9 PF14658.6 PVD32855.1 - 0.11 12.8 0.0 8.9 6.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain HEPN_AbiA_CTD PF18732.1 PVD32855.1 - 8.7 6.3 7.0 7.2 6.6 0.2 3.0 3 0 0 3 3 3 0 HEPN like, Abia C-terminal domain Sulfotransfer_1 PF00685.27 PVD32856.1 - 1.4e-68 231.2 7.4 1.8e-46 158.8 2.0 3.8 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32856.1 - 1e-11 45.6 0.1 2.6e-06 28.0 0.0 3.9 1 1 3 4 4 4 2 Sulfotransferase family Gln_deamidase_2 PF18626.1 PVD32856.1 - 0.05 13.9 1.3 1.2 9.4 0.0 3.2 4 0 0 4 4 4 0 Glutaminase Sulfotransfer_1 PF00685.27 PVD32857.1 - 4.6e-52 177.1 1.8 4.4e-51 173.9 1.8 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32857.1 - 1.6e-06 28.7 0.0 4.3e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family SF3A3 PF16837.5 PVD32857.1 - 0.026 15.0 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 FliG_C PF01706.16 PVD32857.1 - 0.11 12.7 0.2 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 FliG C-terminal domain Sulfotransfer_1 PF00685.27 PVD32858.1 - 1e-50 172.7 1.2 7.3e-50 169.9 1.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32858.1 - 2.5e-05 24.8 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family SF3A3 PF16837.5 PVD32858.1 - 0.099 13.2 0.1 0.22 12.1 0.1 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Sulfotransfer_1 PF00685.27 PVD32859.1 - 4e-41 141.3 0.2 4.3e-40 137.9 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32859.1 - 4.2e-05 24.0 0.0 0.0001 22.8 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32860.1 - 7.7e-51 173.1 5.1 1.1e-49 169.3 5.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32860.1 - 7.1e-07 29.8 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family SF3A3 PF16837.5 PVD32860.1 - 0.0052 17.3 0.4 0.014 15.9 0.4 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 B3_4 PF03483.17 PVD32861.1 - 7e-06 25.8 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain DUF4525 PF15027.6 PVD32861.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Vault PF01505.18 PVD32862.1 - 2.2e-64 213.4 8.2 9.7e-19 67.3 0.1 5.2 6 0 0 6 6 6 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 PVD32862.1 - 2.1e-55 185.8 0.2 4e-55 184.9 0.2 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 PVD32862.1 - 3.3e-38 129.5 2.2 3.6e-34 116.6 0.0 4.4 3 1 1 4 4 4 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 PVD32862.1 - 4.6e-38 129.4 0.6 8.8e-25 86.9 0.2 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 PVD32862.1 - 1.1e-31 108.7 0.1 6.7e-30 103.0 0.1 3.4 4 0 0 4 4 4 1 Major Vault Protein repeat domain B3_4 PF03483.17 PVD32862.1 - 0.00071 19.3 0.7 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 1 B3/4 domain DUF3601 PF12208.8 PVD32862.1 - 0.025 14.6 0.0 8.2 6.6 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3601) FYVE PF01363.21 PVD32863.1 - 3.5e-05 23.9 12.9 0.00011 22.2 12.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger HeH PF12949.7 PVD32863.1 - 0.0028 17.3 0.1 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 HeH/LEM domain Armet PF10208.9 PVD32863.1 - 0.051 13.5 3.6 2.4 8.1 0.8 2.6 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding zf-B_box PF00643.24 PVD32863.1 - 9.5 6.5 12.7 50 4.2 12.7 2.3 1 1 0 1 1 1 0 B-box zinc finger Exo5 PF09810.9 PVD32864.1 - 1.7e-46 159.4 15.1 4.1e-20 72.6 0.6 3.7 1 1 2 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 PVD32864.1 - 0.035 14.0 0.4 0.081 12.8 0.1 1.7 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily NTP_transf_8 PF12281.8 PVD32865.1 - 0.027 14.5 0.3 0.043 13.8 0.3 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Antistasin PF02822.14 PVD32866.1 - 4.2e-10 40.1 178.2 0.29 11.8 9.8 11.4 10 1 0 10 10 10 10 Antistasin family LIM_bind PF01803.16 PVD32866.1 - 0.4 10.2 19.8 7.5 6.0 0.2 7.1 4 3 5 9 9 9 0 LIM-domain binding protein Methyltr_RsmF_N PF17125.5 PVD32866.1 - 1 9.9 4.7 29 5.3 0.1 4.2 3 1 3 6 6 6 0 N-terminal domain of 16S rRNA methyltransferase RsmF Antistasin PF02822.14 PVD32867.1 - 4.3e-30 104.0 124.8 1.2e-08 35.5 10.8 8.1 8 1 0 8 8 8 6 Antistasin family SNF PF00209.18 PVD32868.1 - 5e-158 527.0 30.0 6.5e-158 526.7 30.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Glyco_transf_7N PF13733.6 PVD32869.1 - 1.8e-39 134.5 0.2 2.6e-39 133.9 0.2 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD32869.1 - 7.2e-21 73.6 0.8 1.3e-20 72.8 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ABC_membrane PF00664.23 PVD32870.1 - 5.6e-56 190.2 39.7 1.3e-34 120.2 12.2 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD32870.1 - 1.1e-50 171.7 0.1 7.4e-28 97.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD32870.1 - 1.8e-08 34.1 0.4 0.17 11.3 0.1 4.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD32870.1 - 5.3e-05 23.2 0.1 0.14 11.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PVD32870.1 - 8.4e-05 22.2 1.2 0.016 14.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 PVD32870.1 - 0.0002 21.5 0.8 0.011 15.9 0.1 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PVD32870.1 - 0.00025 21.1 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 PVD32870.1 - 0.0005 20.2 1.1 0.1 12.7 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 PVD32870.1 - 0.0011 18.9 0.7 0.01 15.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PVD32870.1 - 0.0017 18.6 2.3 2.6 8.3 0.1 3.5 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 PVD32870.1 - 0.0026 16.6 0.1 1.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 PVD32870.1 - 0.0033 17.9 0.2 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 PVD32870.1 - 0.0051 16.2 0.8 3 7.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 PVD32870.1 - 0.0052 17.2 0.1 0.47 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 PVD32870.1 - 0.0074 15.6 0.1 0.098 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 PVD32870.1 - 0.009 15.8 0.3 0.16 11.6 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PVD32870.1 - 0.0094 15.5 0.1 0.098 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PVD32870.1 - 0.02 14.7 0.9 0.96 9.2 0.2 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase CENP-B_dimeris PF09026.10 PVD32870.1 - 0.024 15.0 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_7 PF12775.7 PVD32870.1 - 0.04 13.4 0.4 5 6.6 0.1 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 PVD32870.1 - 0.049 13.8 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PVD32870.1 - 0.053 12.6 0.1 11 4.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 PVD32870.1 - 0.11 11.7 0.1 12 5.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF1770 PF08589.10 PVD32870.1 - 0.36 11.8 4.7 6.8 7.7 1.2 3.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Spt4 PF06093.13 PVD32871.1 - 3.1e-25 88.1 0.3 4e-25 87.7 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-Tim10_DDP PF02953.15 PVD32872.1 - 3e-21 74.8 0.4 3e-21 74.8 0.4 1.7 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Inj_translocase PF16928.5 PVD32872.1 - 0.025 14.0 0.2 0.027 13.9 0.2 1.0 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome HisKA_3 PF07730.13 PVD32872.1 - 0.034 14.7 0.7 0.051 14.1 0.2 1.6 2 0 0 2 2 2 0 Histidine kinase zf-TRAF PF02176.18 PVD32873.1 - 2.1e-06 28.3 5.7 2.1e-06 28.3 5.7 5.2 4 1 1 5 5 5 3 TRAF-type zinc finger zf-C2HC_2 PF13913.6 PVD32873.1 - 0.082 12.8 0.1 0.082 12.8 0.1 6.6 7 1 0 7 7 7 0 zinc-finger of a C2HC-type XAF1_C PF18608.1 PVD32873.1 - 0.13 11.9 0.0 0.13 11.9 0.0 4.1 5 0 0 5 5 5 0 XIAP-associated factor 1 C-terminal domain zf-FPG_IleRS PF06827.14 PVD32873.1 - 0.27 11.1 6.8 1.5 8.7 0.4 3.6 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 PVD32873.1 - 1.4 8.6 28.5 0.37 10.4 1.0 6.8 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger DUF2318 PF10080.9 PVD32873.1 - 2.8 8.1 12.5 18 5.5 0.0 4.0 2 1 2 4 4 4 0 Predicted membrane protein (DUF2318) PH PF00169.29 PVD32874.1 - 3.4e-16 59.6 0.4 7.4e-16 58.6 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 PVD32874.1 - 1.9e-06 27.9 0.0 5.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD32874.1 - 5.2e-05 23.6 3.7 0.00038 20.8 1.7 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 PVD32874.1 - 0.00078 19.7 0.1 0.0019 18.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Metallopep PF12044.8 PVD32875.1 - 1.1e-84 284.6 0.0 2.5e-84 283.4 0.0 1.5 2 0 0 2 2 2 1 Putative peptidase family Reprolysin_5 PF13688.6 PVD32875.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 CH PF00307.31 PVD32876.1 - 6.1e-20 71.4 0.0 3.5e-19 69.0 0.0 2.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD32876.1 - 0.00012 21.8 5.8 0.00028 20.7 0.0 4.2 5 0 0 5 5 5 1 CAMSAP CH domain ArsP_1 PF03773.13 PVD32876.1 - 0.32 10.1 0.0 28 3.7 0.1 2.4 2 0 0 2 2 2 0 Predicted permease PROCN PF08083.11 PVD32879.1 - 3e-220 731.0 8.9 3e-220 731.0 8.9 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 PVD32879.1 - 2.1e-110 367.8 1.1 4e-110 366.9 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 PVD32879.1 - 3.2e-90 300.2 2.7 7.3e-90 299.0 2.7 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 PVD32879.1 - 1.1e-85 285.2 9.1 1.1e-85 285.1 7.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 PVD32879.1 - 2.7e-74 247.6 0.0 6.4e-74 246.4 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 PVD32879.1 - 2.5e-54 182.4 0.1 6.6e-54 181.1 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 PVD32879.1 - 3.1e-48 162.1 0.5 8.9e-48 160.6 0.5 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 PVD32879.1 - 4.1e-11 42.9 0.0 1.1e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRNT PF15174.6 PVD32880.1 - 0.043 13.8 0.2 3 7.9 0.1 2.8 2 0 0 2 2 2 0 Prion-related protein testis-specific PHD PF00628.29 PVD32881.1 - 1e-16 60.5 27.1 1.3e-09 37.8 12.2 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 PVD32881.1 - 6.2e-13 48.2 0.2 1.3e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain FHA PF00498.26 PVD32881.1 - 0.00085 19.6 0.4 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 FHA domain PHD_2 PF13831.6 PVD32881.1 - 0.0027 17.2 17.2 0.021 14.4 0.2 3.5 2 1 1 3 3 3 2 PHD-finger C1_1 PF00130.22 PVD32881.1 - 2.1 8.3 21.9 0.27 11.2 5.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PAS_6 PF08348.11 PVD32882.1 - 0.0051 16.7 0.4 0.016 15.0 0.4 1.9 1 0 0 1 1 1 1 YheO-like PAS domain DUF3128 PF11326.8 PVD32883.1 - 2.6e-14 53.3 2.6 2.6e-14 53.3 2.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) Kinesin PF00225.23 PVD32885.1 - 8.5e-98 327.3 0.0 1.4e-97 326.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD32885.1 - 3.2e-22 79.1 1.5 1.1e-21 77.4 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding Cep57_CLD_2 PF14197.6 PVD32885.1 - 0.7 10.0 16.6 18 5.5 0.1 3.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 PVD32885.1 - 0.84 8.9 8.0 0.083 12.2 2.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 PVD32885.1 - 4.1 7.7 11.7 24 5.2 0.9 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 PVD32885.1 - 4.9 6.9 21.1 0.74 9.6 14.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 PVD32885.1 - 5.6 7.1 19.2 3.5 7.8 0.5 5.0 4 1 1 5 5 5 0 bZIP transcription factor Oxysterol_BP PF01237.18 PVD32886.1 - 1.7e-125 418.8 0.1 2.7e-125 418.1 0.1 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 PVD32886.1 - 1.7e-05 25.0 0.1 4.9e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 PVD32886.1 - 0.0039 17.7 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 PH domain HlyD_D23 PF16576.5 PVD32886.1 - 0.0074 15.5 0.8 0.015 14.5 0.8 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PH_6 PF15406.6 PVD32886.1 - 0.019 15.2 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain MOZART2 PF12926.7 PVD32887.1 - 3.4e-28 97.1 0.3 4.8e-28 96.6 0.3 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF5331 PF17265.2 PVD32887.1 - 0.014 15.1 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Sec39 PF08314.11 PVD32887.1 - 0.027 12.9 0.6 0.032 12.7 0.6 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 B9-C2 PF07162.11 PVD32888.1 - 2.3e-45 154.8 0.1 4.2e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Myb_DNA-binding PF00249.31 PVD32890.1 - 1.4e-20 73.2 0.5 2.4e-12 46.8 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain GPS2_interact PF15784.5 PVD32890.1 - 5e-20 71.7 7.4 5e-20 71.7 7.4 3.1 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-bind_6 PF13921.6 PVD32890.1 - 7.3e-06 26.1 12.8 0.0011 19.2 0.5 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Lzipper-MIP1 PF14389.6 PVD32890.1 - 0.015 15.6 0.4 0.08 13.3 0.4 2.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF5082 PF16888.5 PVD32890.1 - 0.065 13.5 2.5 0.22 11.8 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Myb_DNA-bind_7 PF15963.5 PVD32890.1 - 9.9 6.1 19.4 0.16 11.9 0.6 3.0 3 0 0 3 3 3 0 Myb DNA-binding like Nt_Gln_amidase PF09764.9 PVD32891.1 - 1.3e-47 161.8 0.0 2e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal glutamine amidase Peptidase_M10 PF00413.24 PVD32892.1 - 3.1e-59 199.3 0.1 6.5e-59 198.3 0.1 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 PVD32892.1 - 1.7e-32 111.1 20.8 1.3e-11 44.2 4.3 4.5 4 0 0 4 4 4 4 Hemopexin Astacin PF01400.24 PVD32892.1 - 0.005 16.5 0.2 0.41 10.2 0.1 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 PVD32892.1 - 0.0094 15.6 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 PVD32892.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD32892.1 - 0.024 15.1 0.1 0.047 14.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 PVD32892.1 - 0.036 13.3 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 PVD32892.1 - 0.079 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 PVD32892.1 - 0.14 11.1 0.3 0.24 10.3 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Phage-A118_gp45 PF10653.9 PVD32895.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Glyco_hydro_63 PF03200.16 PVD32896.1 - 9e-09 34.6 2.8 0.00014 20.7 0.1 3.9 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain ZNRF_3_ecto PF18212.1 PVD32897.1 - 5.9e-39 132.3 0.0 1.8e-38 130.7 0.0 1.8 2 0 0 2 2 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 PVD32897.1 - 1.7e-13 50.6 5.9 1.7e-13 50.6 5.9 2.6 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD32897.1 - 5.1e-10 39.0 5.5 5.1e-10 39.0 5.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PVD32897.1 - 2.6e-08 33.5 2.8 2.6e-08 33.5 2.8 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PVD32897.1 - 5.6e-08 32.5 3.6 5.6e-08 32.5 3.6 2.9 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD32897.1 - 2.1e-06 27.9 7.3 2.1e-06 27.9 7.3 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD32897.1 - 0.00015 21.7 3.2 0.00015 21.7 3.2 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD32897.1 - 0.00015 21.7 4.3 0.00015 21.7 4.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD32897.1 - 0.00022 21.0 3.2 0.00086 19.1 3.2 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PVD32897.1 - 0.0012 18.7 2.1 0.0012 18.7 2.1 2.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PVD32897.1 - 0.11 12.3 2.7 0.38 10.6 2.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain pEK499_p136 PF18736.1 PVD32897.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 HEPN pEK499 p136 zf-C3H2C3 PF17122.5 PVD32897.1 - 0.48 10.5 4.4 1.7 8.7 4.4 2.0 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 PVD32897.1 - 0.82 9.8 10.1 0.061 13.4 4.4 2.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PVD32897.1 - 2.3 8.4 6.0 37 4.6 6.0 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PVD32897.1 - 3.4 7.4 9.5 0.8 9.4 4.1 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 PVD32897.1 - 4 7.7 7.3 10 6.4 4.3 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Amb_V_allergen PF03913.13 PVD32898.1 - 0.18 11.8 3.1 0.6 10.1 3.1 1.9 1 0 0 1 1 1 0 Amb V Allergen Cys_rich_CPXG PF14255.6 PVD32898.1 - 1.2 9.1 8.4 0.83 9.6 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich CPXCG Autoind_bind PF03472.15 PVD32900.1 - 0.051 13.0 0.2 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 Autoinducer binding domain NDUF_B12 PF08122.12 PVD32901.1 - 1.1 9.3 3.7 2.1 8.4 0.4 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.32 PVD32904.1 - 1e-58 193.9 21.9 5.7e-09 36.5 0.0 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD32904.1 - 2e-23 82.5 2.1 2.8e-05 24.3 0.1 6.6 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 PVD32904.1 - 1.3e-12 48.0 0.6 2.9e-12 46.9 0.6 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 PVD32904.1 - 2e-06 27.9 0.0 0.016 15.1 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD32904.1 - 2.3e-06 26.8 0.0 0.0077 15.2 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PVD32904.1 - 2.7e-05 23.1 4.1 5.5 5.5 0.7 4.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 PVD32904.1 - 0.00015 21.2 0.0 0.52 9.6 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Nbas_N PF15492.6 PVD32904.1 - 0.0038 16.6 0.7 8.2 5.7 0.1 4.0 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1682 PF07946.14 PVD32905.1 - 0.0041 16.4 0.8 0.0066 15.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1754 PF08555.10 PVD32906.1 - 6.1 7.7 17.7 5 8.0 16.9 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) VWA PF00092.28 PVD32908.1 - 1.1e-08 35.5 0.0 1.3e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD32908.1 - 3.1e-07 31.0 0.0 3.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD32909.1 - 0.014 16.1 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain E1-N PF14463.6 PVD32909.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 E1 N-terminal domain DUF3915 PF13054.6 PVD32909.1 - 0.78 9.7 2.9 0.99 9.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Laminin_G_3 PF13385.6 PVD32910.1 - 0.06 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Ras PF00071.22 PVD32911.1 - 9e-43 145.7 0.1 1.1e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD32911.1 - 3.9e-30 104.5 0.0 7.3e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD32911.1 - 7.5e-10 38.5 0.0 9.9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD32911.1 - 8.4e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD32911.1 - 0.0028 17.0 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 PVD32911.1 - 0.059 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_L23eN PF03939.13 PVD32912.1 - 1.4e-21 76.4 12.8 1.4e-21 76.4 12.8 2.8 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 PVD32912.1 - 2.5e-14 53.4 1.8 2.5e-14 53.4 1.8 2.2 3 0 0 3 3 3 1 Ribosomal protein L23 RuvA_C PF07499.13 PVD32912.1 - 0.039 14.4 0.6 0.11 12.9 0.6 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain MCPVI PF02993.14 PVD32912.1 - 1.7 8.4 9.1 0.39 10.5 5.9 1.5 2 0 0 2 2 2 0 Minor capsid protein VI DUF4291 PF14124.6 PVD32913.1 - 5.6e-50 169.7 0.5 1e-49 168.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) TFIID-18kDa PF02269.16 PVD32913.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Lyase_1 PF00206.20 PVD32914.1 - 2.3e-99 332.7 0.0 1.8e-98 329.8 0.0 2.0 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 PVD32914.1 - 4.1e-22 78.7 0.0 1.1e-21 77.3 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CCDC117 PF15810.5 PVD32915.1 - 2.2e-12 47.5 2.0 4.3e-12 46.5 2.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 Vps53_N PF04100.12 PVD32916.1 - 2.8e-155 517.0 0.7 7e-155 515.7 0.1 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 PVD32916.1 - 1.5e-08 34.3 0.2 3.9e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 PVD32916.1 - 1.9e-05 24.7 1.0 0.00029 20.8 0.0 2.9 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 PVD32916.1 - 0.00026 20.0 0.6 0.00026 20.0 0.6 2.1 3 0 0 3 3 3 1 Spc7 kinetochore protein Laminin_II PF06009.12 PVD32916.1 - 0.00082 19.4 1.1 0.0026 17.8 1.1 1.8 1 0 0 1 1 1 1 Laminin Domain II NBD94 PF16830.5 PVD32916.1 - 0.00098 19.5 1.3 0.0024 18.2 1.3 1.7 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH Vps51 PF08700.11 PVD32916.1 - 0.002 18.2 0.4 0.086 12.9 0.0 3.5 2 1 1 3 3 2 1 Vps51/Vps67 LXG PF04740.12 PVD32916.1 - 0.014 15.1 1.9 0.12 12.1 0.4 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily Sec8_exocyst PF04048.14 PVD32916.1 - 0.022 14.6 0.3 0.074 12.9 0.3 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain GrpE PF01025.19 PVD32916.1 - 0.024 14.3 0.3 0.1 12.3 0.3 2.1 1 0 0 1 1 1 0 GrpE CAP_N PF01213.19 PVD32916.1 - 0.04 13.4 4.2 4.7 6.6 1.7 2.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BORCS8 PF10167.9 PVD32916.1 - 0.063 13.2 3.5 1.6 8.7 0.2 3.8 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 DUF5355 PF17306.2 PVD32916.1 - 0.072 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5355) Sec34 PF04136.15 PVD32916.1 - 0.089 12.7 0.3 0.48 10.3 0.3 2.3 1 0 0 1 1 1 0 Sec34-like family DUF5082 PF16888.5 PVD32916.1 - 0.097 12.9 0.6 2.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CPG4 PF15481.6 PVD32916.1 - 0.12 13.1 0.7 0.43 11.2 0.7 1.9 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 XhlA PF10779.9 PVD32916.1 - 0.48 10.7 7.3 0.095 12.9 2.4 2.5 3 0 0 3 3 2 0 Haemolysin XhlA SlyX PF04102.12 PVD32916.1 - 2.7 8.7 4.5 1.3e+02 3.2 0.1 4.1 2 1 2 4 4 4 0 SlyX ATG16 PF08614.11 PVD32916.1 - 3.2 7.9 7.1 0.59 10.3 1.2 2.6 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 PVD32916.1 - 4 7.5 7.0 1.8 8.7 1.3 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 PVD32916.1 - 5.3 7.1 8.1 8.8 6.4 3.5 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) SOG2 PF10428.9 PVD32916.1 - 6.9 5.7 7.2 0.44 9.7 0.2 2.3 3 0 0 3 3 3 0 RAM signalling pathway protein HA2 PF04408.23 PVD32917.1 - 1.1e-19 70.7 0.0 1.1e-19 70.7 0.0 3.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD32917.1 - 1.7e-17 63.6 0.0 6.3e-17 61.7 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD32917.1 - 5e-12 46.1 0.0 7.1e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD32917.1 - 3.4e-08 33.5 0.0 3.4e-08 33.5 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD32917.1 - 3.9e-05 23.9 0.0 0.00017 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PVD32917.1 - 0.00019 21.8 0.0 0.0006 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PVD32917.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PVD32917.1 - 0.015 14.7 3.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 0 KaiC Flavi_DEAD PF07652.14 PVD32917.1 - 0.14 12.1 0.3 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain ABC_tran PF00005.27 PVD32917.1 - 1.4 9.5 0.0 1.4 9.5 0.0 2.9 3 0 0 3 3 3 0 ABC transporter FAD_binding_4 PF01565.23 PVD32918.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 PVD32918.1 - 4.3e-06 26.8 0.9 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase 7tm_1 PF00001.21 PVD32919.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Kunitz_BPTI PF00014.23 PVD32920.1 - 4.7e-18 65.2 7.2 5.4e-18 65.0 7.2 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain 4HPAD_g_N PF18671.1 PVD32920.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal MNR PF15718.5 PVD32921.1 - 1.6e-60 205.3 29.8 6.6e-44 150.3 18.1 5.4 2 2 1 4 4 4 3 Protein moonraker MDMPI_N PF11716.8 PVD32921.1 - 0.37 11.5 2.8 0.9 10.2 0.4 2.8 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Unstab_antitox PF09720.10 PVD32921.1 - 0.98 9.5 5.7 1.4 9.0 0.9 3.3 3 0 0 3 3 3 0 Putative addiction module component Myosin_head PF00063.21 PVD32922.1 - 4.3e-158 527.6 0.7 2.9e-81 273.7 0.1 3.0 2 1 1 3 3 3 2 Myosin head (motor domain) IQ PF00612.27 PVD32922.1 - 0.0046 16.6 32.2 0.97 9.4 0.8 6.6 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_22 PF13401.6 PVD32922.1 - 0.0048 17.2 0.0 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_6 PF12774.7 PVD32922.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 PVD32922.1 - 0.035 13.6 0.0 0.096 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PVD32922.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Hpr_kinase_C PF07475.12 PVD32922.1 - 0.12 11.9 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TsaE PF02367.17 PVD32922.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PVD32922.1 - 0.31 11.4 2.4 0.41 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain IL17 PF06083.11 PVD32923.1 - 8.4e-17 61.4 0.5 1.5e-16 60.6 0.5 1.4 1 0 0 1 1 1 1 Interleukin-17 HEPN_DZIP3 PF18738.1 PVD32924.1 - 2.7e-29 101.8 0.0 5.3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN NACHT PF05729.12 PVD32924.1 - 3.5e-12 46.5 2.4 7.1e-11 42.3 0.2 3.3 3 0 0 3 3 3 1 NACHT domain CARD PF00619.21 PVD32924.1 - 8.9e-06 25.7 1.4 6.9e-05 22.8 0.1 2.7 2 0 0 2 2 2 1 Caspase recruitment domain AAA_22 PF13401.6 PVD32924.1 - 0.00027 21.2 0.0 0.0034 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD32924.1 - 0.00053 20.4 1.6 0.0039 17.6 0.2 3.1 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 PVD32924.1 - 0.0058 16.4 0.6 0.047 13.4 0.0 2.9 2 1 1 3 3 3 1 IstB-like ATP binding protein SWI2_SNF2 PF18766.1 PVD32924.1 - 0.0095 15.6 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_25 PF13481.6 PVD32924.1 - 0.059 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD32924.1 - 0.098 13.2 0.0 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter CARD_2 PF16739.5 PVD32924.1 - 0.11 12.4 0.2 0.48 10.4 0.0 2.3 2 1 0 2 2 2 0 Caspase recruitment domain Peptidase_M14 PF00246.24 PVD32925.1 - 2.5e-59 201.4 0.0 2.2e-41 142.5 0.0 2.0 1 1 1 2 2 2 2 Zinc carboxypeptidase AstE_AspA PF04952.14 PVD32925.1 - 0.00036 19.7 0.1 0.00062 18.9 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CarboxypepD_reg PF13620.6 PVD32925.1 - 0.0011 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Sulfotransfer_3 PF13469.6 PVD32927.1 - 6.4e-47 160.7 0.0 1e-46 160.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32927.1 - 1.2e-07 31.5 0.0 4.8e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 PVD32927.1 - 0.0059 16.5 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain TMEM219 PF14940.6 PVD32927.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane 219 Radical_SAM PF04055.21 PVD32929.1 - 3.5e-28 99.1 0.1 7.4e-26 91.5 0.0 3.1 3 0 0 3 3 3 1 Radical SAM superfamily Wyosine_form PF08608.12 PVD32929.1 - 3.5e-28 97.7 0.2 9.9e-28 96.3 0.0 1.9 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.25 PVD32929.1 - 5.6e-27 94.7 0.2 1.3e-26 93.5 0.2 1.7 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 PVD32929.1 - 0.0041 17.4 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 Flavodoxin domain Hydrolase PF00702.26 PVD32929.1 - 0.11 12.7 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Flavodoxin_NdrI PF07972.11 PVD32929.1 - 0.17 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like EGF PF00008.27 PVD32930.1 - 2.1e-52 175.0 188.9 1.3e-08 35.0 6.5 13.9 14 0 0 14 14 14 12 EGF-like domain hEGF PF12661.7 PVD32930.1 - 5e-17 61.8 169.7 8.9e-06 26.1 6.8 16.0 16 0 0 16 16 16 10 Human growth factor-like EGF CBM_14 PF01607.24 PVD32930.1 - 3.7e-14 52.6 9.5 3e-09 36.9 1.4 8.3 7 4 2 9 9 9 2 Chitin binding Peritrophin-A domain EGF_2 PF07974.13 PVD32930.1 - 4.4e-12 46.1 177.7 0.0043 17.4 8.3 12.8 11 1 0 11 11 11 8 EGF-like domain zf-Di19 PF05605.12 PVD32931.1 - 3.5e-05 24.0 26.2 0.024 14.9 0.3 5.5 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 PVD32931.1 - 0.0015 18.3 1.5 0.0015 18.3 1.5 4.7 5 0 0 5 5 5 2 C2H2-type zinc-finger domain T-box PF00907.22 PVD32936.1 - 2.1e-64 217.2 0.1 2.8e-64 216.7 0.1 1.1 1 0 0 1 1 1 1 T-box PALP PF00291.25 PVD32937.1 - 2.7e-73 246.9 0.0 3.3e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LIM PF00412.22 PVD32939.1 - 2.3e-62 207.1 42.9 1.1e-16 60.8 1.7 4.3 4 0 0 4 4 4 4 LIM domain Paxillin PF03535.13 PVD32939.1 - 4e-10 39.9 4.2 4e-10 39.9 4.2 3.1 3 1 0 3 3 3 1 Paxillin family Vps39_2 PF10367.9 PVD32939.1 - 0.047 14.1 10.1 0.083 13.3 0.0 4.1 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 Gin PF10764.9 PVD32939.1 - 3.6 7.6 12.5 5.1 7.1 0.1 4.8 5 0 0 5 5 5 0 Inhibitor of sigma-G Gin Sgf11 PF08209.11 PVD32939.1 - 6.2 6.5 10.2 55 3.4 0.1 4.9 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Antimicrobial17 PF08129.11 PVD32944.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta enterocin family C2 PF00168.30 PVD32951.1 - 2.6e-44 149.7 1.0 3.8e-22 78.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 PVD32951.1 - 5.7e-34 117.7 1.2 7.6e-33 114.0 0.1 2.5 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase BTK PF00779.19 PVD32951.1 - 2.8e-10 39.8 2.4 5.1e-10 39.0 2.4 1.5 1 0 0 1 1 1 1 BTK motif PH PF00169.29 PVD32951.1 - 4.4e-06 27.1 0.0 2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 PH domain MRP-S35 PF10246.9 PVD32951.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Metallophos PF00149.28 PVD32952.1 - 5.7e-26 92.3 0.1 1.1e-25 91.4 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 PVD32952.1 - 1.1e-08 34.0 0.1 5.2e-07 28.8 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD32952.1 - 6.3e-08 32.9 0.7 3.2e-05 24.3 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD32952.1 - 9e-08 31.5 0.2 3.6e-05 23.4 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PVD32952.1 - 8.1e-06 25.6 0.1 0.00012 21.8 0.1 2.8 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD32952.1 - 9.1e-05 21.8 0.1 0.00074 18.9 0.0 2.4 2 0 0 2 2 2 1 EF hand STPPase_N PF16891.5 PVD32952.1 - 0.18 12.3 0.4 0.38 11.2 0.4 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-HIT PF04438.16 PVD32953.1 - 2.2e-08 33.8 13.9 3.7e-08 33.1 13.9 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 PVD32953.1 - 4.3 7.5 18.7 1.1 9.4 15.6 1.7 2 0 0 2 2 2 0 MYND finger Sulfotransfer_1 PF00685.27 PVD32954.1 - 2.3e-40 138.8 0.0 2.6e-39 135.3 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32954.1 - 0.0019 18.6 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Gly_transf_sug PF04488.15 PVD32955.1 - 5.8e-05 23.6 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RVT_1 PF00078.27 PVD32958.1 - 2.2e-17 63.3 0.0 3.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 PVD32960.1 - 2.5e-16 59.7 0.0 4.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 PVD32960.1 - 0.0023 18.5 0.0 0.0077 16.8 0.0 1.8 2 0 0 2 2 2 1 T5orf172 domain FANCL_C PF11793.8 PVD32960.1 - 0.0098 16.1 3.3 0.02 15.1 3.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 PVD32960.1 - 0.011 15.9 0.8 0.025 14.8 0.8 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Vps39_2 PF10367.9 PVD32960.1 - 0.016 15.7 0.6 0.034 14.6 0.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.29 PVD32960.1 - 0.029 14.2 3.3 0.057 13.3 3.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-ACC PF17848.1 PVD32960.1 - 0.055 13.6 1.1 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain MUG113 PF13455.6 PVD32960.1 - 0.061 14.0 0.8 0.39 11.4 0.0 2.4 3 0 0 3 3 3 0 Meiotically up-regulated gene 113 zf-HC5HC2H_2 PF13832.6 PVD32960.1 - 0.066 13.4 0.9 0.15 12.2 0.9 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 PVD32960.1 - 0.13 12.2 5.1 0.35 10.9 5.1 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 PVD32960.1 - 0.61 10.1 6.0 1.1 9.3 1.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L36 PF00444.18 PVD32960.1 - 0.96 9.7 0.0 0.96 9.7 0.0 4.2 5 0 0 5 5 5 0 Ribosomal protein L36 SAPS PF04499.15 PVD32963.1 - 2.2 7.0 7.2 4 6.1 7.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EF-hand_4 PF12763.7 PVD32968.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Tom5 PF10642.9 PVD32968.1 - 0.31 11.1 2.5 1 9.5 2.5 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase RR_TM4-6 PF06459.12 PVD32968.1 - 3.2 7.5 15.5 0.72 9.6 2.8 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rhodanese PF00581.20 PVD32970.1 - 1.5e-32 112.3 0.0 2e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain LRR_6 PF13516.6 PVD32971.1 - 0.11 12.6 4.5 13 6.2 0.3 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 PVD32971.1 - 0.24 12.1 7.6 8.8 7.3 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD32971.1 - 0.33 10.7 13.0 0.063 13.1 0.8 3.5 2 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 PVD32971.1 - 1.3 9.6 15.5 0.076 13.5 1.7 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) TUDOR PF00567.24 PVD32972.1 - 6.8e-26 90.7 0.4 3.3e-25 88.5 0.0 2.4 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.29 PVD32972.1 - 2.8e-12 46.3 0.0 8.7e-12 44.7 0.0 2.0 1 0 0 1 1 1 1 KH domain EcoEI_R_C PF08463.10 PVD32972.1 - 0.058 13.5 0.2 0.58 10.3 0.1 2.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal ParB_C PF18064.1 PVD32972.1 - 0.15 12.3 0.3 22 5.3 0.0 3.4 4 0 0 4 4 4 0 Centromere-binding protein ParB C-terminal DUF4275 PF14101.6 PVD32972.1 - 0.3 11.2 1.9 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4275) zf-C2H2_12 PF18658.1 PVD32972.1 - 1.7 8.3 5.5 2.9 7.5 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger C2H2-type Pkinase PF00069.25 PVD32973.1 - 9.4e-65 218.6 0.0 1.5e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD32973.1 - 3.3e-49 167.5 0.0 5.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 PVD32973.1 - 6.8e-20 71.5 2.8 1.4e-19 70.5 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 PVD32973.1 - 2.9e-05 23.5 0.0 6.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD32973.1 - 0.00016 21.1 0.8 0.0045 16.3 0.0 3.1 3 1 0 3 3 3 1 Kinase-like RIO1 PF01163.22 PVD32973.1 - 0.00038 20.1 0.2 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PVD32973.1 - 0.0033 17.4 0.0 0.094 12.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD32973.1 - 0.0097 14.7 0.0 0.027 13.3 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase MIT PF04212.18 PVD32973.1 - 0.7 10.0 3.7 1.7 8.8 0.2 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain APH PF01636.23 PVD32974.1 - 2.2e-49 168.6 0.0 1.3e-48 166.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 PVD32974.1 - 1.6e-25 90.1 2.3 3.6e-25 88.9 2.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PVD32974.1 - 1.9e-20 72.8 0.0 4.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD32974.1 - 1.4e-09 38.6 0.4 1.1e-08 35.7 0.1 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD32974.1 - 5.5e-08 33.2 1.3 1.7e-07 31.6 1.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Choline_kinase PF01633.20 PVD32974.1 - 8.7e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 PVD32974.1 - 0.00016 21.1 0.1 0.00036 19.9 0.1 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase HAD_2 PF13419.6 PVD32974.1 - 0.00047 20.3 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF1679 PF07914.11 PVD32974.1 - 0.05 12.5 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) IL17 PF06083.11 PVD32976.1 - 2.2e-10 40.9 3.1 5e-10 39.7 3.1 1.6 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 PVD32977.1 - 5.2e-15 55.7 0.9 9.2e-15 54.9 0.9 1.3 1 0 0 1 1 1 1 Interleukin-17 DUF971 PF06155.12 PVD32977.1 - 0.17 12.6 0.5 0.44 11.2 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) IL17 PF06083.11 PVD32978.1 - 7.2e-14 52.0 5.3 7.2e-14 52.0 5.3 1.8 2 0 0 2 2 2 1 Interleukin-17 IL17 PF06083.11 PVD32979.1 - 9.3e-05 22.8 6.1 0.00012 22.5 1.0 3.2 3 2 0 3 3 3 1 Interleukin-17 HTH_Tnp_Tc5 PF03221.16 PVD32980.1 - 5.1e-09 36.0 0.0 5.4e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain IL17 PF06083.11 PVD32980.1 - 2.8e-08 34.1 2.3 1.3e-07 32.0 2.3 2.0 1 1 0 1 1 1 1 Interleukin-17 CENP-B_N PF04218.13 PVD32980.1 - 3.2e-06 26.7 0.5 3.2e-06 26.7 0.5 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DDE_1 PF03184.19 PVD32980.1 - 0.00022 20.9 1.5 0.0039 16.8 0.5 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 PVD32980.1 - 0.0012 18.6 0.1 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 PVD32980.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.6 PVD32980.1 - 0.02 15.0 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 PVD32980.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Bot1p PF12298.8 PVD32980.1 - 0.081 13.1 0.0 0.081 13.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein HTH_Tnp_1 PF01527.20 PVD32980.1 - 0.17 12.2 0.0 0.17 12.2 0.0 2.4 3 0 0 3 3 3 0 Transposase IL17 PF06083.11 PVD32981.1 - 5.4e-09 36.4 3.0 6.5e-09 36.1 1.2 2.0 2 0 0 2 2 2 1 Interleukin-17 IL17 PF06083.11 PVD32982.1 - 5e-12 46.1 1.4 8.9e-12 45.3 1.4 1.4 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 PVD32983.1 - 4.7e-13 49.4 4.2 7.6e-13 48.7 4.2 1.3 1 0 0 1 1 1 1 Interleukin-17 Rabaptin PF03528.15 PVD32984.1 - 3.3e-75 253.7 57.0 8.2e-51 173.2 21.8 5.4 5 1 0 5 5 5 3 Rabaptin Rab5-bind PF09311.11 PVD32984.1 - 1.5e-72 244.6 58.6 1.5e-72 244.6 58.6 5.7 3 2 1 5 5 5 1 Rabaptin-like protein FYVE PF01363.21 PVD32984.1 - 1.9e-15 56.7 11.7 1.9e-15 56.7 11.7 2.1 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 PVD32984.1 - 0.068 13.4 5.9 0.22 11.7 5.9 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF99 PF01949.16 PVD32984.1 - 6.4 6.1 6.4 0.89 8.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 zf-RING_2 PF13639.6 PVD32984.1 - 6.9 7.1 11.4 16 6.0 11.4 1.7 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 PVD32984.1 - 7 6.8 8.8 6.4e+02 0.5 7.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 PVD32984.1 - 7.9 6.5 17.6 0.52 10.3 12.6 1.7 2 0 0 2 2 2 0 zinc-RING finger domain 7tm_3 PF00003.22 PVD32985.1 - 2.8e-33 115.6 17.1 2.8e-33 115.6 17.1 2.2 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD32985.1 - 1.5e-16 60.5 1.8 2.6e-16 59.7 1.8 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SKICH PF17751.1 PVD32986.1 - 1.5e-19 70.5 0.5 3.1e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 PVD32986.1 - 5.5e-12 45.7 0.2 7.9e-12 45.2 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECW_N PF16562.5 PVD32986.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 NUDIX PF00293.28 PVD32988.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain 7tm_1 PF00001.21 PVD32989.1 - 4.7e-12 45.8 10.3 4.7e-12 45.8 10.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD32989.1 - 1.2e-09 37.9 21.2 2.8e-08 33.4 21.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD32989.1 - 3.6e-05 23.5 7.9 3.6e-05 23.5 7.9 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-C2H2_4 PF13894.6 PVD32990.1 - 0.00017 22.1 13.5 0.014 16.2 0.4 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD32990.1 - 0.0017 18.7 11.8 0.65 10.6 0.2 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type Paramyxo_P PF01806.17 PVD32990.1 - 0.0034 16.9 0.3 0.0042 16.6 0.3 1.3 1 0 0 1 1 1 1 Paramyxovirinae P phosphoprotein C-terminal region zf-H2C2_2 PF13465.6 PVD32990.1 - 0.09 13.2 4.9 0.85 10.2 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 PVD32990.1 - 0.98 9.8 7.4 27 5.2 6.5 3.0 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 PVD32990.1 - 3.1 7.9 7.7 1.6e+02 2.4 7.7 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 PVD32990.1 - 7.7 6.6 6.1 20 5.3 0.0 3.3 3 1 0 3 3 3 0 BED zinc finger DUF4598 PF15370.6 PVD32990.1 - 8.2 7.0 9.4 4.7 7.7 7.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4598) Galactosyl_T PF01762.21 PVD32991.1 - 5.2e-38 130.8 0.0 6.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sulfotransfer_1 PF00685.27 PVD32992.1 - 3.6e-38 131.6 0.0 4.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32992.1 - 3.8e-05 24.2 0.0 6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family HTH_18 PF12833.7 PVD32992.1 - 0.054 13.8 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Sulfotransfer_1 PF00685.27 PVD32993.1 - 8.8e-49 166.4 0.1 5.3e-48 163.8 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32993.1 - 3.6e-07 30.8 0.0 1.3e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family HTH_18 PF12833.7 PVD32993.1 - 0.069 13.4 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Sulfotransfer_1 PF00685.27 PVD32994.1 - 5.6e-46 157.2 0.0 5.1e-45 154.0 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32994.1 - 3.6e-05 24.2 0.0 5.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32995.1 - 1.4e-44 152.6 0.0 2.6e-43 148.4 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32995.1 - 4.2e-05 24.0 0.0 7.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD32996.1 - 3.9e-41 141.3 0.1 5.2e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32996.1 - 0.0004 20.9 0.0 0.00068 20.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family 2_5_RNA_ligase2 PF13563.6 PVD32996.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily GRP PF07172.11 PVD32998.1 - 1.2 9.8 19.2 18 6.1 19.2 2.1 1 1 0 1 1 1 0 Glycine rich protein family Sulfotransfer_1 PF00685.27 PVD32999.1 - 8.9e-51 172.9 0.1 9.4e-50 169.6 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD32999.1 - 7.3e-10 39.6 0.0 1.4e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD33000.1 - 5.4e-42 144.1 0.0 6.8e-41 140.5 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD33000.1 - 8.9e-07 29.5 0.0 1.7e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF4735 PF15882.5 PVD33001.1 - 1.5e-67 228.1 0.2 2.1e-67 227.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) CLAMP PF14769.6 PVD33002.1 - 1.3e-36 125.0 4.7 2.3e-36 124.2 4.7 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Rad51 PF08423.11 PVD33003.1 - 2.8e-47 161.1 0.0 4.3e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PVD33003.1 - 6.6e-09 35.6 0.0 1.2e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 PVD33003.1 - 1.7e-06 27.6 0.1 4.5e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 KaiC RecA PF00154.21 PVD33003.1 - 0.00015 21.4 0.3 0.00065 19.2 0.1 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 PVD33003.1 - 0.0051 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PP2C PF00481.21 PVD33004.1 - 1e-38 133.5 0.0 3.4e-25 89.2 0.0 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 PVD33004.1 - 0.0008 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C Nitrate_red_del PF02613.15 PVD33004.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit Scramblase PF03803.15 PVD33005.1 - 3.6e-07 29.7 0.1 0.0026 17.1 0.0 2.0 1 1 1 2 2 2 2 Scramblase zf-B_box PF00643.24 PVD33008.1 - 1.5e-09 37.8 8.4 1.5e-09 37.8 8.4 3.5 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 PVD33008.1 - 7e-09 35.8 0.1 4.7e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 MATH domain zf-C3HC4_3 PF13920.6 PVD33008.1 - 0.00025 20.8 16.2 0.00025 20.8 16.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD33008.1 - 0.0061 16.4 17.1 0.0061 16.4 17.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HTH_1 PF00126.27 PVD33008.1 - 0.05 13.6 0.5 0.18 11.7 0.5 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Hemerythrin PF01814.23 PVD33008.1 - 0.5 11.0 2.7 1 10.0 0.6 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain AAA_28 PF13521.6 PVD33009.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YozE_SAM_like PF06855.12 PVD33009.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 YozE SAM-like fold SH2 PF00017.24 PVD33010.1 - 4.8e-14 52.2 0.1 9.9e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain Phe_ZIP PF08916.11 PVD33010.1 - 1.1e-12 48.4 2.9 2.2e-12 47.5 2.9 1.5 1 0 0 1 1 1 1 Phenylalanine zipper PH PF00169.29 PVD33010.1 - 9.1e-10 39.0 0.0 2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Shadoo PF14999.6 PVD33010.1 - 0.74 9.9 6.2 0.12 12.4 1.5 2.1 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective UNC-93 PF05978.16 PVD33011.1 - 2.1e-07 30.8 8.0 2.1e-07 30.8 8.0 2.7 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF1899 PF08953.11 PVD33012.1 - 2.4e-29 101.0 0.0 4.5e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 PVD33012.1 - 2.5e-21 75.3 0.1 3.9e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 PVD33012.1 - 3.3e-11 43.5 6.2 0.00014 22.5 0.9 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD33012.1 - 2.1e-09 37.5 0.5 0.0057 16.9 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PVD33012.1 - 0.018 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain CAT_RBD PF03123.15 PVD33012.1 - 0.03 14.3 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 CAT RNA binding domain Cupin_2 PF07883.11 PVD33013.1 - 6.5e-09 35.4 0.0 9.2e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 PVD33013.1 - 0.0036 17.2 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain ARD PF03079.14 PVD33013.1 - 0.045 13.9 0.3 0.14 12.3 0.3 1.9 1 1 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 PVD33013.1 - 0.05 13.1 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein 7tm_1 PF00001.21 PVD33016.1 - 6e-52 176.6 21.3 6e-52 176.6 21.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD33016.1 - 1.2e-07 31.6 17.0 1.2e-07 31.6 17.0 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD33016.1 - 0.00027 20.8 11.9 0.0047 16.7 6.9 2.8 2 1 0 2 2 2 2 Olfactory receptor DUF3439 PF11921.8 PVD33017.1 - 4.6 7.2 13.2 1.7 8.6 6.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PD40 PF07676.12 PVD33019.1 - 0.0069 16.3 0.3 0.41 10.7 0.1 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Fringe PF02434.16 PVD33020.1 - 9.4e-10 38.3 0.1 5e-09 36.0 0.1 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD33020.1 - 4.7e-05 23.3 0.0 0.00048 20.0 0.0 2.3 1 1 1 2 2 2 1 Galactosyltransferase Phage_TTP_13 PF16463.5 PVD33020.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein family Glyco_trans_2_3 PF13632.6 PVD33020.1 - 0.055 13.4 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 LCE PF14672.6 PVD33020.1 - 0.067 13.8 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 Late cornified envelope Glyco_transf_11 PF01531.16 PVD33021.1 - 2.3e-33 115.7 0.3 2.3e-33 115.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD33021.1 - 2.2e-05 24.3 1.2 3.3e-05 23.8 1.2 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PRKCSH-like PF12999.7 PVD33021.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Hydrolase_4 PF12146.8 PVD33023.1 - 3.4e-05 23.3 0.0 0.0002 20.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD33023.1 - 7e-05 22.6 0.0 0.042 13.5 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PVD33023.1 - 0.00093 18.9 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) EspG PF06872.11 PVD33024.1 - 0.0012 17.5 3.1 0.028 13.0 0.3 2.2 1 1 1 2 2 2 2 EspG protein DUF5013 PF16405.5 PVD33024.1 - 0.019 15.2 5.9 12 6.1 0.1 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF5013) FliG_C PF01706.16 PVD33024.1 - 4.9 7.4 9.9 10 6.3 2.7 2.7 1 1 0 2 2 2 0 FliG C-terminal domain Tubulin_3 PF14881.6 PVD33024.1 - 5.4 6.7 8.1 11 5.7 3.2 2.1 1 1 1 2 2 2 0 Tubulin domain RVT_1 PF00078.27 PVD33025.1 - 0.05 13.1 0.1 0.082 12.4 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF383 PF04063.14 PVD33026.1 - 5.1e-44 150.2 0.0 2.5e-43 148.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 PVD33026.1 - 3.1e-17 62.2 0.0 5.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 PVD33026.1 - 7.9e-05 23.0 0.0 0.0058 17.0 0.0 2.6 2 1 0 2 2 2 1 HEAT repeats ketoacyl-synt PF00109.26 PVD33027.1 - 6e-55 186.6 0.7 6e-55 186.6 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PVD33027.1 - 2.8e-24 85.4 0.5 5.6e-24 84.4 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PVD33027.1 - 9e-07 28.5 0.2 1.8e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain IreB PF06135.12 PVD33027.1 - 0.081 13.1 0.0 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 IreB regulatory phosphoprotein Sugar_tr PF00083.24 PVD33029.1 - 4.6e-30 104.9 13.0 6.2e-30 104.4 13.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD33029.1 - 3.9e-25 88.5 25.7 1.3e-20 73.7 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.6 PVD33029.1 - 0.38 10.1 2.0 0.73 9.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Glyco_hydro_18 PF00704.28 PVD33030.1 - 1e-83 281.7 0.5 1.5e-83 281.1 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pyr_redox_2 PF07992.14 PVD33031.1 - 2e-50 171.7 0.0 3.3e-50 171.0 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD33031.1 - 2.5e-15 56.8 1.2 2.8e-11 43.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PVD33031.1 - 3.5e-12 46.5 0.2 3.8e-06 27.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_binding_2 PF00890.24 PVD33031.1 - 4.3e-08 32.7 2.2 1.2e-05 24.6 0.9 3.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 PVD33031.1 - 2.5e-07 30.2 0.4 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD33031.1 - 4.7e-06 26.0 0.3 0.0011 18.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 PVD33031.1 - 7.8e-06 24.8 2.0 0.0007 18.4 0.7 3.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 PVD33031.1 - 0.0038 16.7 0.2 0.0051 16.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PVD33031.1 - 0.013 15.1 2.6 0.4 10.2 2.6 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 PVD33031.1 - 0.013 14.6 3.5 0.05 12.7 2.9 2.2 1 1 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PVD33031.1 - 0.017 14.5 0.4 0.055 12.8 0.4 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 PVD33031.1 - 0.03 14.5 0.6 0.065 13.5 0.6 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PVD33031.1 - 0.045 13.0 0.5 0.085 12.1 0.5 1.4 1 0 0 1 1 1 0 Thi4 family SNARE_assoc PF09335.11 PVD33032.1 - 2.9e-08 34.2 0.1 1.6e-07 31.8 0.1 2.2 1 1 0 1 1 1 1 SNARE associated Golgi protein EST1_DNA_bind PF10373.9 PVD33033.1 - 1.1e-58 199.0 0.0 1.8e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 PVD33033.1 - 7.5e-23 81.3 0.8 2.8e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 PIN domain EST1 PF10374.9 PVD33033.1 - 1.6e-15 57.9 0.0 1e-14 55.3 0.0 2.5 1 1 0 1 1 1 1 Telomerase activating protein Est1 Tugs PF17840.1 PVD33033.1 - 0.026 14.7 0.4 0.087 13.0 0.4 1.9 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain PIN_9 PF18477.1 PVD33033.1 - 0.051 13.9 0.0 1.7 9.0 0.0 2.9 2 0 0 2 2 2 0 PIN like domain TPR_17 PF13431.6 PVD33033.1 - 0.17 12.3 0.1 14 6.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33033.1 - 0.23 11.7 2.4 5.4 7.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF155 PF02582.14 PVD33034.1 - 3.7e-22 79.2 0.2 6.9e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MAM33 PF02330.16 PVD33035.1 - 8e-31 107.6 4.6 1e-30 107.3 4.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein adh_short PF00106.25 PVD33036.1 - 9.1e-22 77.5 0.4 1.7e-21 76.6 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD33036.1 - 1.1e-12 48.0 0.1 1.9e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD33036.1 - 3.1e-05 24.0 0.9 4.2e-05 23.5 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PVD33036.1 - 0.0032 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PVD33036.1 - 0.046 12.8 0.1 0.075 12.1 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain SAT PF16073.5 PVD33036.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF2888 PF11135.8 PVD33036.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) NIPSNAP PF07978.13 PVD33037.1 - 3.2e-22 78.7 0.3 1.4e-14 54.1 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP DUF4200 PF13863.6 PVD33038.1 - 8.4e-22 77.8 24.6 8.4e-22 77.8 24.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) DUF5082 PF16888.5 PVD33038.1 - 0.011 16.0 0.7 0.011 16.0 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4559 PF15112.6 PVD33038.1 - 0.044 13.4 14.6 0.014 15.1 9.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) EF-hand_1 PF00036.32 PVD33040.1 - 2.2e-06 26.8 6.6 0.033 13.7 0.0 5.3 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 PVD33040.1 - 2.5e-06 27.9 8.4 0.08 13.4 0.0 4.8 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD33040.1 - 1.1e-05 24.9 15.7 0.56 10.3 0.1 6.7 4 2 3 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 PVD33040.1 - 0.00011 22.0 0.6 0.065 13.1 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD33040.1 - 0.072 12.6 0.1 0.072 12.6 0.1 5.3 5 0 0 5 5 5 0 EF hand Branch PF02485.21 PVD33041.1 - 4.6e-36 124.6 0.1 6.2e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Nab6_mRNP_bdg PF10567.9 PVD33041.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA-recognition motif 7tm_1 PF00001.21 PVD33043.1 - 7.1e-18 64.9 1.2 1.2e-17 64.2 1.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD33044.1 - 2.6e-06 26.9 0.0 2.7e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD33045.1 - 0.00016 21.1 0.3 0.00019 20.8 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GHMP_kinases_N PF00288.26 PVD33046.1 - 3.8e-17 62.3 0.1 9.5e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PVD33046.1 - 1.2e-06 28.8 0.0 3.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2621 PF11084.8 PVD33046.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) NACHT PF05729.12 PVD33047.1 - 5.2e-05 23.2 0.2 0.00016 21.7 0.2 1.8 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 PVD33047.1 - 0.033 15.1 0.7 1.1e+02 3.9 0.0 5.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Glycolytic PF00274.19 PVD33048.1 - 6.4e-177 587.5 0.0 7.2e-177 587.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I GHMP_kinases_C PF08544.13 PVD33048.1 - 0.26 11.7 1.5 0.44 10.9 0.3 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal Glycolytic PF00274.19 PVD33049.1 - 3.6e-180 598.2 0.0 4.1e-180 598.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I FERM_M PF00373.18 PVD33050.1 - 2.6e-12 47.2 1.1 4.4e-12 46.5 1.1 1.4 1 0 0 1 1 1 1 FERM central domain RA PF00788.23 PVD33050.1 - 0.096 13.3 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Metallophos PF00149.28 PVD33051.1 - 4.4e-22 79.6 0.6 4.4e-22 79.6 0.6 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 PVD33051.1 - 1.5e-05 24.9 0.4 1.5e-05 24.9 0.4 1.8 2 0 0 2 2 2 1 Saposin-like type B, region 1 Metallophos_2 PF12850.7 PVD33051.1 - 3.2e-05 24.2 0.0 0.012 15.8 0.0 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Rhodanese PF00581.20 PVD33052.1 - 1.7e-12 47.8 0.0 2.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3342 PF11822.8 PVD33053.1 - 3.5e-36 123.3 1.6 7.5e-36 122.2 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 PVD33053.1 - 0.00073 19.7 0.5 0.0017 18.6 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Myb_DNA-binding PF00249.31 PVD33053.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf_UBZ PF18439.1 PVD33053.1 - 0.08 12.5 0.1 0.57 9.8 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rogdi_lz PF10259.9 PVD33055.1 - 8e-29 100.9 2.9 1.1e-28 100.5 2.9 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Helicase_IV_N PF12462.8 PVD33055.1 - 0.017 15.0 8.1 0.07 13.1 3.9 2.8 3 0 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal UPF0231 PF06062.11 PVD33055.1 - 3.6 7.9 5.9 4.4 7.6 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0231) KH_1 PF00013.29 PVD33056.1 - 0.0026 17.5 0.4 0.0064 16.3 0.1 1.7 2 0 0 2 2 2 1 KH domain PBP PF01161.20 PVD33057.1 - 2.3e-07 31.2 0.2 3.6e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L16 PF00252.18 PVD33058.1 - 7.7e-29 100.4 0.0 1.2e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CGI-121 PF08617.10 PVD33059.1 - 1e-31 110.3 0.7 1.1e-31 110.1 0.7 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 His_Phos_1 PF00300.22 PVD33060.1 - 4.3e-21 75.5 1.0 4.6e-19 68.9 1.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 PVD33061.1 - 4.2e-22 78.6 0.0 6.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PVD33061.1 - 8.3e-06 26.0 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PVD33061.1 - 1.1e-05 25.8 0.1 0.00032 21.1 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Phospholip_B PF04916.13 PVD33062.1 - 1.7e-152 508.7 4.6 1.8e-150 502.1 4.6 2.0 1 1 0 1 1 1 1 Phospholipase B YqhG PF11079.8 PVD33062.1 - 0.036 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Acyl-CoA_dh_1 PF00441.24 PVD33063.1 - 5.7e-36 124.0 5.8 7.9e-36 123.5 5.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PVD33063.1 - 1.6e-18 66.7 0.0 3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PVD33063.1 - 2e-14 54.2 0.0 4.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PVD33063.1 - 1.1e-13 51.6 5.7 1.3e-13 51.4 5.2 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1907 PF08925.11 PVD33064.1 - 4.1e-121 403.8 0.0 4.8e-121 403.5 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) ketoacyl-synt PF00109.26 PVD33065.1 - 4.7e-47 160.7 5.9 4.8e-47 160.7 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PVD33065.1 - 1.4e-31 108.9 0.2 2.8e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PVD33065.1 - 9.8e-07 28.4 0.2 1.9e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 PVD33065.1 - 0.013 15.9 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension IreB PF06135.12 PVD33065.1 - 0.25 11.6 0.0 0.69 10.2 0.0 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein DUF383 PF04063.14 PVD33066.1 - 1e-50 172.0 0.2 6.5e-49 166.2 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 PVD33066.1 - 4.3e-17 61.7 0.0 8.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 PVD33066.1 - 2.6e-06 27.7 0.1 0.00017 21.9 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PVD33066.1 - 0.022 15.0 0.1 2.2 8.8 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.23 PVD33066.1 - 0.079 13.0 0.2 4.5 7.4 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 PVD33066.1 - 0.079 13.4 1.8 3.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.7 PVD33066.1 - 0.17 11.9 1.8 0.33 11.0 0.1 2.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 GPCR_chapero_1 PF11904.8 PVD33068.1 - 2.5e-84 283.3 0.1 2.2e-49 168.6 0.0 2.4 1 1 1 2 2 2 2 GPCR-chaperone Ank_2 PF12796.7 PVD33068.1 - 1.3e-10 41.7 0.0 2.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33068.1 - 2.9e-09 37.0 0.0 8.7e-05 22.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33068.1 - 2.4e-08 34.3 0.2 4.2e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33068.1 - 2.5e-06 27.4 0.0 0.033 14.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD33068.1 - 1.2e-05 25.5 0.0 0.00088 19.6 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat RAP80_UIM PF18282.1 PVD33068.1 - 0.074 12.8 14.6 0.13 12.0 8.2 3.4 2 1 1 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 PVD33068.1 - 0.12 12.3 39.3 0.17 11.9 5.8 5.5 5 0 0 5 5 5 0 Ubiquitin interaction motif BCL9 PF11502.8 PVD33069.1 - 0.019 14.7 9.3 2.4 8.1 0.2 3.2 3 0 0 3 3 3 0 B-cell lymphoma 9 protein HLH PF00010.26 PVD33071.1 - 1.4e-13 50.5 0.6 1.1e-12 47.7 0.2 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Syntaxin PF00804.25 PVD33071.1 - 0.01 15.5 0.6 0.022 14.4 0.6 1.4 1 0 0 1 1 1 0 Syntaxin Sec2p PF06428.11 PVD33071.1 - 0.091 12.7 0.7 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PagP PF07017.11 PVD33072.1 - 0.059 12.8 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Syntaxin PF00804.25 PVD33073.1 - 7.7e-62 208.5 18.4 7.7e-62 208.5 18.4 12.9 4 2 11 15 15 11 2 Syntaxin Pkinase PF00069.25 PVD33073.1 - 1.7e-59 201.3 0.1 2e-58 197.9 0.0 3.1 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 PVD33073.1 - 2.8e-34 119.0 0.0 6.8e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 PVD33073.1 - 4.5e-29 101.5 0.0 2.6e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 PVD33073.1 - 1.4e-10 41.6 0.2 2.1e-09 37.8 0.0 3.1 2 0 0 2 2 2 1 PH domain SNARE PF05739.19 PVD33073.1 - 1.6e-10 40.8 8.5 2.4e-10 40.2 1.0 3.6 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 PVD33073.1 - 2.4e-10 40.7 5.4 2.4e-10 40.7 5.4 14.8 7 3 8 15 15 11 1 Syntaxin-like protein C1_1 PF00130.22 PVD33073.1 - 1.4e-08 34.5 3.0 3.2e-08 33.3 3.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF948 PF06103.11 PVD33073.1 - 0.0064 16.7 2.2 0.0064 16.7 2.2 13.2 12 3 2 14 14 14 2 Bacterial protein of unknown function (DUF948) Pkinase_C PF00433.24 PVD33073.1 - 0.043 14.5 0.5 0.12 13.1 0.5 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain FYVE PF01363.21 PVD33073.1 - 0.12 12.5 1.1 0.38 10.9 1.1 1.9 1 0 0 1 1 1 0 FYVE zinc finger WBS_methylT PF12589.8 PVD33074.1 - 2.5e-20 73.0 3.7 4.7e-20 72.1 3.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 PVD33074.1 - 1.3e-13 51.4 0.0 2.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD33074.1 - 1.1e-12 48.5 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD33074.1 - 2.8e-06 27.2 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD33074.1 - 1.1e-05 26.1 0.0 4.2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD33074.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD33074.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 PVD33074.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 PVD33074.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 PVD33074.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DnaJ PF00226.31 PVD33075.1 - 2.9e-21 75.4 0.5 6.1e-21 74.3 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Rad60-SLD PF11976.8 PVD33076.1 - 2e-15 56.4 0.1 3.4e-12 46.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PVD33076.1 - 0.072 12.8 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Glyco_transf_17 PF04724.13 PVD33076.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 17 ERM PF00769.19 PVD33077.1 - 8.2e-73 245.2 27.0 8.2e-73 245.2 27.0 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 PVD33077.1 - 1e-27 96.3 1.2 1.6e-27 95.7 0.0 2.0 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_M PF00373.18 PVD33077.1 - 2.5e-25 89.2 0.4 2.5e-25 89.2 0.4 2.7 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 PVD33077.1 - 1.8e-13 50.2 0.7 8.1e-13 48.1 0.1 2.4 2 0 0 2 2 2 1 FERM N-terminal domain ACBP PF00887.19 PVD33077.1 - 0.0084 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein UPF0449 PF15136.6 PVD33077.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 zf-C4H2 PF10146.9 PVD33077.1 - 7.6 6.8 24.6 0.31 11.3 2.7 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein SBDS_C PF09377.10 PVD33078.1 - 2e-37 127.7 0.4 2.8e-37 127.2 0.4 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 PVD33078.1 - 7.3e-19 67.6 0.5 1.6e-18 66.5 0.5 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HTH_22 PF13309.6 PVD33078.1 - 0.031 14.4 0.2 0.069 13.2 0.2 1.6 1 0 0 1 1 1 0 HTH domain Pex2_Pex12 PF04757.14 PVD33079.1 - 4.7e-37 127.7 0.3 6.1e-37 127.4 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region ProQ PF04352.13 PVD33079.1 - 0.036 13.9 0.1 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 ProQ/FINO family Adaptin_N PF01602.20 PVD33080.1 - 4.6e-65 220.2 1.5 6.3e-65 219.7 1.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.10 PVD33080.1 - 2.7e-32 111.2 0.5 7.9e-32 109.7 0.1 2.0 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.20 PVD33080.1 - 8e-12 45.5 0.7 8e-12 45.5 0.7 2.3 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd3 PF12719.7 PVD33080.1 - 3.4e-06 26.5 0.2 5.3e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 PVD33080.1 - 6.7e-06 26.4 0.6 0.013 15.8 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.7 PVD33080.1 - 0.0097 16.0 1.2 4.7 7.2 0.1 2.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 PVD33080.1 - 0.033 13.8 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 CLASP N terminal M20_dimer PF07687.14 PVD33080.1 - 0.13 12.2 0.0 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 Peptidase dimerisation domain SPC25 PF06703.11 PVD33080.1 - 0.14 11.9 0.0 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SNF5 PF04855.12 PVD33081.1 - 2.2e-57 194.6 1.0 3.9e-31 108.7 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Isochorismatase PF00857.20 PVD33082.1 - 5.9e-15 55.9 0.6 7.8e-15 55.5 0.6 1.1 1 0 0 1 1 1 1 Isochorismatase family AlaDh_PNT_N PF05222.15 PVD33082.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain BTB_2 PF02214.22 PVD33083.1 - 3.5e-14 52.9 0.0 7.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PVD33083.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain tRNA_bind_4 PF18490.1 PVD33084.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA-binding domain Y_phosphatase3 PF13350.6 PVD33085.1 - 2e-45 155.6 0.0 2.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PVD33085.1 - 1.1e-07 31.5 0.1 3.8e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 PVD33085.1 - 0.031 13.2 0.0 0.061 12.2 0.0 1.5 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain ABC_membrane PF00664.23 PVD33086.1 - 4.3e-62 210.2 6.2 8.5e-62 209.3 6.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PVD33086.1 - 1.5e-35 122.7 0.0 3.2e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD33086.1 - 9.7e-07 28.4 4.0 1.2e-05 24.9 0.1 2.5 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MENTAL PF10457.9 PVD33086.1 - 9.5e-06 25.5 3.6 9.5e-06 25.5 3.6 2.4 2 0 0 2 2 2 1 Cholesterol-capturing domain AAA_24 PF13479.6 PVD33086.1 - 0.0013 18.5 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PVD33086.1 - 0.0022 18.4 0.1 0.0096 16.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 PVD33086.1 - 0.0054 16.5 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_29 PF13555.6 PVD33086.1 - 0.0083 15.9 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PVD33086.1 - 0.015 14.5 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 PVD33086.1 - 0.02 14.8 0.0 0.068 13.1 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 PVD33086.1 - 0.067 13.5 0.2 0.66 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 PVD33086.1 - 0.08 12.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PVD33086.1 - 0.15 11.9 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 PVD33087.1 - 4e-63 213.2 0.0 5.6e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33087.1 - 2.7e-32 112.1 0.0 3.6e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD33087.1 - 2.3e-05 23.5 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD33087.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD33087.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD33087.1 - 0.0018 17.6 0.0 0.007 15.7 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase PF00069.25 PVD33088.1 - 2.7e-57 194.1 0.0 2.7e-57 194.1 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33088.1 - 1.6e-36 125.9 0.6 6.3e-36 124.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PVD33088.1 - 0.083 12.8 0.0 0.083 12.8 0.0 3.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Myotub-related PF06602.14 PVD33089.1 - 9.1e-117 389.9 4.0 3.7e-115 384.6 4.0 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 PVD33089.1 - 5.2e-17 61.8 9.6 2.2e-16 59.7 9.6 2.2 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase3 PF13350.6 PVD33089.1 - 0.0033 17.4 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.16 PVD33089.1 - 0.008 16.4 5.2 0.32 11.2 4.8 2.8 2 0 0 2 2 2 1 FYVE-type zinc finger Myosin_tail_1 PF01576.19 PVD33091.1 - 2.6e-29 101.8 27.1 7.8e-16 57.1 12.5 2.0 1 1 1 2 2 2 2 Myosin tail Sec8_exocyst PF04048.14 PVD33091.1 - 0.0042 17.0 0.6 0.0042 17.0 0.6 1.6 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Glyco_transf_9 PF01075.17 PVD33091.1 - 0.0074 15.6 0.7 0.0082 15.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Ribosomal_S15 PF00312.22 PVD33091.1 - 0.017 15.3 4.1 0.57 10.4 0.3 2.6 2 1 0 2 2 2 0 Ribosomal protein S15 DUF1707 PF08044.11 PVD33091.1 - 0.051 13.7 1.6 0.13 12.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DUF4094 PF13334.6 PVD33091.1 - 0.088 13.2 6.0 3.2 8.2 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CSN7a_helixI PF18392.1 PVD33091.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Bacillus_HBL PF05791.11 PVD33091.1 - 0.32 10.8 8.0 0.1 12.4 2.8 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 PVD33091.1 - 0.38 11.2 21.7 0.45 10.9 21.7 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 PVD33091.1 - 0.85 9.7 20.2 4.9 7.2 5.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LTXXQ PF07813.12 PVD33091.1 - 0.91 10.3 13.9 0.047 14.4 5.8 2.4 1 1 2 3 3 3 0 LTXXQ motif family protein DUF724 PF05266.14 PVD33091.1 - 1.2 9.0 18.2 2.1 8.1 7.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Nup88 PF10168.9 PVD33092.1 - 0.35 8.6 0.0 0.42 8.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore component RT_RNaseH_2 PF17919.1 PVD33093.1 - 6.7e-33 112.7 0.0 1.1e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD33093.1 - 8.4e-29 100.0 0.1 1.4e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PVD33093.1 - 1.8e-21 76.0 0.1 1.6e-20 73.0 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD33093.1 - 0.0082 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Hydrolase_4 PF12146.8 PVD33095.1 - 5.8e-05 22.5 0.0 0.00032 20.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD33095.1 - 0.00011 22.0 0.2 0.058 13.0 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PVD33095.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PhoR PF11808.8 PVD33095.1 - 0.23 11.9 3.1 0.74 10.3 3.1 1.8 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR DUF108 PF01958.18 PVD33096.1 - 7e-23 80.8 0.0 1.3e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 PVD33096.1 - 1e-09 39.1 0.0 1.9e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Metallophos PF00149.28 PVD33097.1 - 5.5e-41 141.3 0.1 7.1e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD33097.1 - 1.2e-23 83.2 1.6 2.3e-23 82.4 1.0 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ank_2 PF12796.7 PVD33098.1 - 8.2e-39 132.1 1.6 1.4e-14 54.4 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33098.1 - 1.6e-25 89.2 8.1 8.3e-08 32.6 0.3 6.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33098.1 - 3.7e-24 84.5 8.6 7.3e-09 35.7 0.5 6.6 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33098.1 - 2.6e-22 76.5 7.1 0.00017 21.8 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 PVD33098.1 - 9.8e-19 66.9 14.9 0.00011 22.5 0.1 7.4 8 0 0 8 8 8 5 Ankyrin repeat P2X_receptor PF00864.19 PVD33099.1 - 2.7e-121 405.1 0.2 3.3e-121 404.8 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor TMEM192 PF14802.6 PVD33099.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 TMEM192 family Rad1 PF02144.16 PVD33100.1 - 1.3e-69 234.3 3.3 2e-69 233.7 3.3 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Myb_DNA-binding PF00249.31 PVD33100.1 - 3.1e-10 40.1 0.4 6.2e-10 39.1 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD33100.1 - 2.4e-06 27.7 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 PVD33100.1 - 0.0009 19.5 0.1 0.0044 17.3 0.1 2.3 1 1 0 1 1 1 1 SWIRM domain Not3 PF04065.15 PVD33100.1 - 0.0046 16.4 0.9 0.0078 15.7 0.9 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Helicase_C_2 PF13307.6 PVD33101.1 - 2.9e-42 144.7 0.1 5.8e-27 94.9 0.0 2.6 1 1 1 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.15 PVD33101.1 - 3e-21 75.8 17.0 2.3e-16 59.9 1.0 3.5 2 1 1 3 3 3 2 DEAD_2 DEAD PF00270.29 PVD33101.1 - 1.2e-05 25.2 0.2 0.00017 21.4 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PVD33101.1 - 1.3e-05 25.2 0.0 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HBB PF06777.11 PVD33101.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain Spermine_synth PF01564.17 PVD33102.1 - 2e-64 216.5 0.0 2.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PVD33102.1 - 2.8e-22 78.4 0.1 5.5e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PVD33102.1 - 6.5e-05 23.6 0.1 0.00041 21.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PVD33102.1 - 0.00026 20.6 0.0 0.00034 20.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 PVD33102.1 - 0.00071 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 PVD33102.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD33102.1 - 0.0056 17.4 0.0 0.013 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD33102.1 - 0.034 14.8 0.1 0.079 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 PVD33102.1 - 0.048 12.9 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Urocanase_N PF17391.2 PVD33102.1 - 0.2 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Urocanase N-terminal domain DUF1325 PF07039.11 PVD33103.1 - 2.3e-36 124.8 0.0 4.7e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain SIMPL PF04402.14 PVD33103.1 - 0.011 16.2 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Tudor_3 PF18115.1 PVD33103.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain zf-H2C2_2 PF13465.6 PVD33104.1 - 2.3e-28 97.3 40.9 4.3e-09 36.4 0.9 7.0 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD33104.1 - 2.6e-18 65.4 51.6 1.1e-06 28.7 3.0 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33104.1 - 1.4e-15 56.6 50.3 0.00083 20.0 2.9 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD33104.1 - 7e-11 42.1 29.6 0.01 16.1 0.4 6.0 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD33104.1 - 5.4e-09 36.2 32.7 0.013 15.8 0.3 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD33104.1 - 3.7e-06 26.8 43.1 0.00051 20.0 2.8 6.6 6 1 0 6 6 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 PVD33104.1 - 4e-05 23.8 25.7 0.06 13.6 6.6 3.3 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 PVD33104.1 - 0.00072 19.9 29.6 0.19 12.0 3.0 5.6 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 PVD33104.1 - 0.0076 16.1 27.6 0.24 11.3 2.1 5.7 6 0 0 6 6 6 2 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 PVD33104.1 - 0.011 16.5 17.8 0.76 10.6 5.0 3.6 1 1 2 3 3 3 0 zinc-ribbon family PyrI_C PF02748.15 PVD33104.1 - 0.024 14.5 22.6 0.49 10.4 0.2 5.8 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 PVD33104.1 - 0.048 14.3 21.3 52 4.5 4.4 4.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 PVD33104.1 - 0.049 13.7 21.0 2 8.6 1.0 4.7 4 1 1 5 5 5 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 PVD33104.1 - 0.053 13.3 1.8 0.053 13.3 1.8 5.8 6 0 0 6 6 6 0 zinc-finger C2H2-type HNH_5 PF14279.6 PVD33104.1 - 0.067 13.1 14.4 3.2 7.7 0.1 5.2 5 1 0 5 5 5 0 HNH endonuclease zf-H2C2_5 PF13909.6 PVD33104.1 - 0.069 12.9 1.2 0.069 12.9 1.2 5.7 6 0 0 6 6 6 0 C2H2-type zinc-finger domain FYVE PF01363.21 PVD33104.1 - 0.13 12.5 31.3 0.48 10.6 8.7 3.7 1 1 2 3 3 3 0 FYVE zinc finger YceD PF02620.17 PVD33104.1 - 1 9.5 4.7 2.5 8.2 0.0 3.3 2 1 2 4 4 4 0 Large ribosomal RNA subunit accumulation protein YceD zf-AN1 PF01428.16 PVD33104.1 - 1 9.6 27.4 1 9.6 1.2 6.0 6 0 0 6 6 6 0 AN1-like Zinc finger DUF2256 PF10013.9 PVD33104.1 - 1.1 9.5 22.2 6.4 7.0 0.1 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 PVD33104.1 - 2.3 7.9 18.9 1.4 8.6 0.1 4.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 PVD33104.1 - 3.3 8.5 8.1 32 5.3 0.1 4.1 2 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 PVD33104.1 - 6.1 6.9 15.7 1.3e+02 2.6 9.3 3.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA XPA_N PF01286.18 PVD33104.1 - 10 6.3 21.4 11 6.2 0.1 5.5 6 0 0 6 6 6 0 XPA protein N-terminal zf-B_box PF00643.24 PVD33106.1 - 1.3e-08 34.9 11.3 1.3e-08 34.9 11.3 3.5 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD33106.1 - 1.4e-08 34.6 9.0 1.4e-08 34.6 9.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD33106.1 - 4.5e-07 29.6 12.2 4.5e-07 29.6 12.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD33106.1 - 1.3e-05 25.4 10.6 1.3e-05 25.4 10.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD33106.1 - 6.2e-05 23.1 12.4 6.2e-05 23.1 12.4 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD33106.1 - 0.00051 19.9 11.8 0.00051 19.9 11.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD33106.1 - 0.003 17.4 12.4 0.003 17.4 12.4 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PEP-utilisers_N PF05524.13 PVD33106.1 - 0.056 13.6 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal ARID PF01388.21 PVD33106.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain zf-Sec23_Sec24 PF04810.15 PVD33106.1 - 1.7 8.8 11.7 1.3 9.1 0.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger GST_N PF02798.20 PVD33107.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 PVD33108.1 - 2.5e-17 62.8 25.8 2.4e-15 56.3 14.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD33108.1 - 5e-09 35.5 16.5 6.3e-05 22.0 1.2 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4191 PF13829.6 PVD33108.1 - 0.98 8.7 3.0 1.7 7.9 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Zip PF02535.22 PVD33109.1 - 1.1e-53 182.7 8.8 1.4e-53 182.3 8.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 PVD33110.1 - 4.5e-56 190.5 10.7 5.6e-56 190.2 10.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ninjurin PF04923.12 PVD33110.1 - 4.3 7.3 5.2 0.85 9.6 0.5 2.3 2 0 0 2 2 2 0 Ninjurin Zip PF02535.22 PVD33111.1 - 1.5e-59 201.9 10.6 1.3e-58 198.8 10.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Stevor PF17410.2 PVD33111.1 - 0.11 12.0 1.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF2852 PF11014.8 PVD33112.1 - 0.99 9.6 0.0 0.99 9.6 0.0 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2852) Spem1 PF15670.5 PVD33112.1 - 6.3 6.3 15.2 0.73 9.4 1.9 3.0 3 0 0 3 3 3 0 Spermatid maturation protein 1 XRCC4 PF06632.12 PVD33112.1 - 8.1 5.2 11.6 2.7 6.7 1.5 2.4 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sulfotransfer_1 PF00685.27 PVD33114.1 - 1.4e-49 169.0 0.0 1.3e-48 165.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD33114.1 - 2e-07 31.6 0.0 5.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 PVD33114.1 - 0.026 13.4 0.1 0.035 13.0 0.1 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase DUF2059 PF09832.9 PVD33114.1 - 0.07 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) SpoVIF PF14069.6 PVD33114.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Stage VI sporulation protein F MFS_1 PF07690.16 PVD33115.1 - 5e-22 78.3 2.7 7.8e-22 77.7 2.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GAS2 PF02187.17 PVD33116.1 - 2.9e-30 104.1 0.4 5.7e-30 103.2 0.4 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Prot_ATP_OB_N PF17758.1 PVD33118.1 - 0.15 11.7 0.5 12 5.6 0.1 2.1 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Pkinase_Tyr PF07714.17 PVD33120.1 - 1.8e-49 168.4 0.5 1.1e-47 162.6 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD33120.1 - 1.9e-47 161.9 0.3 3.9e-47 160.8 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain LIM PF00412.22 PVD33120.1 - 3.4e-14 52.8 21.4 1.2e-09 38.3 8.1 2.9 2 0 0 2 2 2 2 LIM domain Kdo PF06293.14 PVD33120.1 - 3.2e-05 23.4 0.2 5.6e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ PF00595.24 PVD33120.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD33120.1 - 0.00013 21.7 0.1 0.00024 20.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD33120.1 - 0.00045 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 PVD33120.1 - 0.0019 18.2 0.0 0.0047 16.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family PDZ_4 PF17816.1 PVD33120.1 - 0.054 13.9 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Kinase-like PF14531.6 PVD33120.1 - 0.075 12.3 0.1 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 PVD33120.1 - 0.12 11.1 0.0 0.27 9.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase B2 PF11473.8 PVD33120.1 - 0.16 11.7 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding protein B2 MIF PF01187.18 PVD33121.1 - 5.1e-25 88.0 0.0 5.6e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MT-A70 PF05063.14 PVD33121.1 - 0.028 14.4 0.0 0.032 14.1 0.0 1.0 1 0 0 1 1 1 0 MT-A70 UFD1 PF03152.14 PVD33122.1 - 5.9e-39 133.3 0.0 7.4e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ATHILA PF03078.15 PVD33122.1 - 0.15 10.8 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family CDC45 PF02724.14 PVD33123.1 - 5.6e-139 464.3 15.9 3e-105 352.9 5.1 3.0 1 1 0 2 2 2 2 CDC45-like protein FmiP_Thoc5 PF09766.9 PVD33124.1 - 8.9e-125 416.7 5.4 4.6e-124 414.4 4.6 2.2 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 Pro_dh PF01619.18 PVD33124.1 - 7.2e-78 262.1 0.0 7.2e-78 262.1 0.0 2.8 2 1 0 2 2 2 1 Proline dehydrogenase DUF1647 PF07801.11 PVD33124.1 - 4.8e-07 29.6 0.2 4.8e-07 29.6 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1647) Ephrin_rec_like PF07699.13 PVD33125.1 - 5.2e-122 397.5 196.9 4.2e-10 39.2 2.5 18.8 2 2 16 19 19 19 18 Putative ephrin-receptor like TNFR_c6 PF00020.18 PVD33125.1 - 8.8e-15 54.8 159.1 0.096 13.1 3.3 20.2 8 3 7 18 18 18 14 TNFR/NGFR cysteine-rich region VSP PF03302.13 PVD33125.1 - 0.00012 21.1 144.8 0.046 12.6 17.5 7.8 2 2 6 8 8 8 7 Giardia variant-specific surface protein DUF2318 PF10080.9 PVD33125.1 - 0.0054 16.8 116.6 0.046 13.8 1.9 12.9 4 2 8 12 12 12 4 Predicted membrane protein (DUF2318) DUF4468 PF14730.6 PVD33125.1 - 0.013 15.8 0.1 7 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold AbiGii_2 PF16873.5 PVD33125.1 - 0.034 12.9 0.3 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGii toxin Asparaginase_2 PF01112.18 PVD33125.1 - 0.059 12.4 18.9 0.16 10.9 0.3 5.1 2 1 0 4 4 4 0 Asparaginase HTH_ABP1_N PF18107.1 PVD33125.1 - 0.17 11.6 2.2 15 5.3 0.2 2.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain BACON PF13004.7 PVD33125.1 - 0.52 10.4 4.2 26 4.9 0.4 3.4 2 0 0 2 2 2 0 Putative binding domain, N-terminal IF-2B PF01008.17 PVD33126.1 - 2.2e-73 246.9 0.0 2.6e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family RhoGAP PF00620.27 PVD33127.1 - 7.7e-45 152.4 0.1 2.4e-44 150.8 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.20 PVD33127.1 - 4.1e-34 118.4 2.6 2.6e-33 115.8 0.7 2.9 3 0 0 3 3 3 1 RhoGEF domain C2 PF00168.30 PVD33127.1 - 6.6e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1708 PF08101.11 PVD33127.1 - 0.0053 16.0 0.0 0.016 14.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) IQ_SEC7_PH PF16453.5 PVD33127.1 - 0.019 14.9 0.5 0.23 11.5 0.1 2.5 2 0 0 2 2 2 0 PH domain PH PF00169.29 PVD33127.1 - 0.33 11.5 2.7 9.1 6.9 2.7 2.6 1 1 0 1 1 1 0 PH domain Lebercilin PF15619.6 PVD33127.1 - 4.6 6.9 8.2 0.66 9.6 3.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease V-SNARE_C PF12352.8 PVD33128.1 - 5.1e-07 29.9 8.8 1.8e-05 24.9 3.2 2.7 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DASH_Duo1 PF08651.10 PVD33128.1 - 0.0018 18.0 3.3 1.3 8.9 0.5 3.0 3 0 0 3 3 3 2 DASH complex subunit Duo1 NPV_P10 PF05531.12 PVD33128.1 - 0.0031 17.9 0.7 2.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF5089 PF17002.5 PVD33128.1 - 0.0071 16.2 8.9 0.017 15.0 4.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5089) Vip3A_N PF12495.8 PVD33128.1 - 0.0071 16.3 0.7 0.06 13.3 0.1 2.1 2 0 0 2 2 2 1 Vegetative insecticide protein 3A N terminal T3SSipB PF16535.5 PVD33128.1 - 0.018 15.5 1.2 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB RasGAP_C PF03836.15 PVD33128.1 - 0.054 13.6 1.6 0.27 11.4 0.2 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Snapin_Pallidin PF14712.6 PVD33128.1 - 0.088 13.2 5.3 1.2 9.6 1.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 PVD33128.1 - 0.16 12.2 4.1 2.5 8.5 0.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mce4_CUP1 PF11887.8 PVD33128.1 - 0.19 11.2 2.2 0.26 10.7 0.2 2.0 2 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 PVD33128.1 - 0.25 11.4 3.2 0.49 10.4 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kinesin PF00225.23 PVD33129.1 - 2.1e-97 326.1 0.2 3.9e-97 325.2 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33129.1 - 5.5e-30 104.3 0.0 1.3e-29 103.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 PVD33129.1 - 2e-08 34.3 0.0 5.1e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 PVD33129.1 - 0.041 14.1 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif EMP24_GP25L PF01105.24 PVD33129.1 - 1.2 9.0 5.6 0.94 9.4 1.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CHCH PF06747.13 PVD33130.1 - 5.2e-06 26.4 6.4 7.8e-06 25.9 6.4 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 PVD33130.1 - 1.1 9.2 18.2 3.5 7.6 18.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) LRR_6 PF13516.6 PVD33131.1 - 4.2e-16 57.5 4.1 0.0022 17.9 0.0 7.3 8 0 0 8 8 8 3 Leucine Rich repeat EF-hand_1 PF00036.32 PVD33131.1 - 1.1e-09 37.1 1.8 0.00078 18.8 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD33131.1 - 4.7e-09 36.6 1.2 1.2e-08 35.2 1.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD33131.1 - 5.2e-09 35.3 4.2 0.00011 21.9 0.1 3.3 1 1 2 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PVD33131.1 - 1.3e-07 31.3 0.7 4.2e-07 29.7 0.7 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD33131.1 - 8.4e-06 25.1 3.4 0.062 12.8 0.4 2.8 2 1 0 2 2 2 2 EF hand LRR_1 PF00560.33 PVD33131.1 - 0.00066 19.9 1.2 5.1 8.0 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 PVD33131.1 - 0.0024 17.6 1.5 1.2 8.9 0.3 3.4 3 1 0 3 3 3 2 Leucine rich repeat zf-CCCH PF00642.24 PVD33132.1 - 2.3e-06 27.3 2.8 3.4e-06 26.8 2.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD33132.1 - 2.7e-05 24.1 4.0 4.4e-05 23.4 4.0 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PVD33132.1 - 0.00015 21.4 4.6 0.00023 20.9 4.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PVD33132.1 - 0.05 14.1 3.7 0.097 13.2 3.7 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF1154 PF06631.11 PVD33132.1 - 0.44 10.6 3.3 0.78 9.8 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Fructosamin_kin PF03881.14 PVD33133.1 - 1.3e-61 208.3 0.8 2.9e-61 207.2 0.8 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 PVD33133.1 - 3.6e-10 40.2 0.0 4.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 PVD33133.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase EcKinase PF02958.20 PVD33133.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase Neisseria_TspB PF05616.13 PVD33134.1 - 0.13 10.8 1.2 0.17 10.3 1.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CXCXC PF03128.14 PVD33134.1 - 1.4 9.6 4.9 52 4.6 0.1 3.8 4 0 0 4 4 4 0 CXCXC repeat Sulfotransfer_1 PF00685.27 PVD33135.1 - 0.037 13.5 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain Sulfotransfer_1 PF00685.27 PVD33136.1 - 3.7e-06 26.6 0.1 0.00041 19.9 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD33136.1 - 0.00039 20.9 0.0 0.00065 20.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Glyco_transf_11 PF01531.16 PVD33137.1 - 3.9e-35 121.5 0.3 5.1e-35 121.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD33137.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF262 PF03235.14 PVD33139.1 - 0.00032 21.0 12.4 0.8 9.8 0.1 6.4 7 0 0 7 7 7 2 Protein of unknown function DUF262 DctA-YdbH PF11739.8 PVD33139.1 - 0.004 16.9 0.1 2.4 7.9 0.1 3.0 1 1 0 1 1 1 1 Dicarboxylate transport Pkinase PF00069.25 PVD33140.1 - 7.5e-63 212.3 0.0 1.2e-62 211.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33140.1 - 5.2e-22 78.4 0.0 9.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD33140.1 - 3e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD33140.1 - 3.7e-05 23.2 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD33140.1 - 0.052 12.3 0.0 0.099 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase PKHD_C PF18331.1 PVD33140.1 - 0.16 12.1 0.1 0.47 10.6 0.1 1.8 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Hydrolase_4 PF12146.8 PVD33142.1 - 5.8e-05 22.5 0.0 0.00032 20.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PVD33142.1 - 0.0001 22.1 0.1 0.058 13.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PVD33142.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_30 PF05430.11 PVD33144.1 - 1.7e-10 40.8 0.3 23 4.9 0.0 10.1 1 1 10 13 13 13 2 S-adenosyl-L-methionine-dependent methyltransferase CEP44 PF15007.6 PVD33144.1 - 0.15 12.2 1.6 1.9e+02 2.2 0.0 6.4 4 4 2 6 6 6 0 Centrosomal spindle body, CEP44 DUF2619 PF10942.8 PVD33144.1 - 1.6 8.8 8.6 1.3e+02 2.8 0.1 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2619) Methyltransf_30 PF05430.11 PVD33145.1 - 4.3e-05 23.4 0.0 7 6.6 0.0 4.3 1 1 2 4 4 4 1 S-adenosyl-L-methionine-dependent methyltransferase AAA_assoc_2 PF16193.5 PVD33145.1 - 0.1 12.9 19.3 34 4.9 0.2 7.3 2 2 8 10 10 10 0 AAA C-terminal domain XAF1_C PF18608.1 PVD33145.1 - 0.23 11.1 7.5 6.4 6.4 0.8 3.6 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain DUF3492 PF11997.8 PVD33145.1 - 0.25 11.1 1.9 57 3.3 0.1 4.3 2 2 1 3 3 3 0 Domain of unknown function (DUF3492) Baculo_LEF-10 PF07206.11 PVD33145.1 - 0.61 10.3 22.9 5.7 7.2 0.0 5.8 2 2 3 5 5 5 0 Baculovirus late expression factor 10 (LEF-10) PHD_2 PF13831.6 PVD33145.1 - 6.8 6.3 18.9 3 7.5 0.1 4.9 7 0 0 7 7 7 0 PHD-finger Methyltransf_30 PF05430.11 PVD33146.1 - 0.00051 19.9 0.0 11 5.9 0.0 4.2 1 1 3 5 5 5 3 S-adenosyl-L-methionine-dependent methyltransferase RNase_P_pop3 PF08228.11 PVD33146.1 - 0.05 13.7 0.1 19 5.2 0.0 3.0 3 1 0 3 3 3 0 RNase P subunit Pop3 DUF4867 PF16161.5 PVD33146.1 - 0.06 12.8 1.8 15 5.0 0.1 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4867) PAS_7 PF12860.7 PVD33146.1 - 0.064 13.4 0.3 65 3.7 0.0 3.6 3 1 1 4 4 4 0 PAS fold Peptidase_S46 PF10459.9 PVD33146.1 - 0.27 9.8 1.1 58 2.1 0.0 4.0 4 2 1 6 6 6 0 Peptidase S46 Baculo_LEF-10 PF07206.11 PVD33146.1 - 1.1 9.5 30.6 15 5.8 0.0 7.9 1 1 8 9 9 9 0 Baculovirus late expression factor 10 (LEF-10) Methyltransf_30 PF05430.11 PVD33147.1 - 0.092 12.6 0.0 15 5.5 0.0 2.9 1 1 2 3 3 3 0 S-adenosyl-L-methionine-dependent methyltransferase AAA_assoc_2 PF16193.5 PVD33147.1 - 0.19 12.1 9.1 11 6.4 0.2 4.6 1 1 3 4 4 4 0 AAA C-terminal domain DMA PF03474.14 PVD33147.1 - 0.31 10.7 18.9 7.3 6.3 0.1 6.8 3 2 4 7 7 7 0 DMRTA motif Baculo_LEF-10 PF07206.11 PVD33147.1 - 3.7 7.8 11.4 16 5.7 1.2 4.0 1 1 3 4 4 4 0 Baculovirus late expression factor 10 (LEF-10) Methyltransf_30 PF05430.11 PVD33148.1 - 9.4e-08 32.0 0.8 43 4.0 0.0 8.1 4 3 4 9 9 9 0 S-adenosyl-L-methionine-dependent methyltransferase DUF1492 PF07374.11 PVD33148.1 - 0.00019 21.6 2.5 58 3.9 0.0 8.0 4 4 6 11 11 11 0 Protein of unknown function (DUF1492) AAA_assoc_2 PF16193.5 PVD33148.1 - 0.29 11.5 42.5 7.4 7.0 0.2 11.4 6 4 3 11 11 11 0 AAA C-terminal domain MF_alpha PF04648.12 PVD33148.1 - 3.3 8.1 4.1 1.1e+02 3.3 0.1 5.5 3 0 0 3 3 3 0 Yeast mating factor alpha hormone DUF3492 PF11997.8 PVD33148.1 - 5.2 6.7 11.9 24 4.5 0.0 6.7 5 4 4 9 9 9 0 Domain of unknown function (DUF3492) Methyltransf_30 PF05430.11 PVD33149.1 - 7.7e-05 22.6 0.3 3.2 7.7 0.0 3.9 1 1 3 4 4 4 2 S-adenosyl-L-methionine-dependent methyltransferase Phage_connect_1 PF05135.13 PVD33149.1 - 0.062 13.8 0.0 78 3.9 0.0 3.4 3 1 0 3 3 3 0 Phage gp6-like head-tail connector protein AAA_assoc_2 PF16193.5 PVD33149.1 - 0.3 11.4 10.6 2.4 8.5 0.3 4.4 1 1 0 4 4 4 0 AAA C-terminal domain DUF3876 PF12992.7 PVD33149.1 - 0.68 10.1 4.1 48 4.1 0.1 4.0 3 1 2 5 5 5 0 Domain of unknown function, B. Theta Gene description (DUF3876) MetRS-N PF09635.10 PVD33149.1 - 1.3 9.6 10.6 28 5.3 0.1 4.2 1 1 3 4 4 4 0 MetRS-N binding domain PH_17 PF18012.1 PVD33149.1 - 4 7.2 11.2 2.2 8.1 0.2 4.1 3 1 2 5 5 5 0 PH domain AAA_assoc_2 PF16193.5 PVD33150.1 - 0.012 15.9 3.7 3.2 8.2 0.1 3.3 1 1 2 3 3 3 0 AAA C-terminal domain DMA PF03474.14 PVD33150.1 - 2 8.1 11.8 3.8 7.2 0.1 5.0 4 1 1 5 5 5 0 DMRTA motif AAA_assoc_2 PF16193.5 PVD33151.1 - 0.95 9.8 19.0 6.4 7.2 0.4 6.2 3 3 2 5 5 5 0 AAA C-terminal domain DUF4731 PF15875.5 PVD33151.1 - 4.6 7.5 13.2 32 4.8 2.7 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4731) GDPD PF03009.17 PVD33152.1 - 1.4e-66 224.9 0.0 1.9e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 PVD33152.1 - 4.3e-06 26.5 0.2 2.6e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 Starch binding domain Hemopexin PF00045.19 PVD33153.1 - 1.6e-20 72.7 2.8 4.5e-07 29.7 0.0 4.4 5 0 0 5 5 5 3 Hemopexin Elf4 PF07011.11 PVD33153.1 - 0.027 14.4 0.5 0.054 13.4 0.5 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain MRPL52 PF18699.1 PVD33154.1 - 0.12 12.5 3.6 2.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Mitoribosomal protein mL52 PBP_sp32 PF07222.12 PVD33154.1 - 0.2 11.1 2.3 0.3 10.5 2.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Dicty_REP PF05086.12 PVD33154.1 - 0.45 8.4 1.2 0.56 8.1 1.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hemopexin PF00045.19 PVD33155.1 - 7e-13 48.3 0.1 6.7e-06 25.9 0.1 3.8 4 0 0 4 4 4 3 Hemopexin Ank_5 PF13857.6 PVD33156.1 - 3.8e-23 81.2 4.5 1.5e-05 25.2 0.0 5.4 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33156.1 - 3e-18 66.2 0.5 0.00081 19.9 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33156.1 - 4.1e-18 65.5 6.2 0.0024 18.4 0.0 6.7 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33156.1 - 1e-16 59.3 4.2 0.032 14.8 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PVD33156.1 - 1.3e-11 44.4 9.9 0.012 16.0 0.1 6.5 7 0 0 7 7 7 3 Ankyrin repeat NO_synthase PF02898.15 PVD33159.1 - 2.3e-106 355.9 0.0 3.3e-106 355.4 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 PVD33159.1 - 7.8e-61 205.5 0.0 1.3e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PVD33159.1 - 3.8e-46 156.9 0.0 8.2e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PVD33159.1 - 3.6e-15 56.6 0.0 8.4e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 PVD33159.1 - 0.0085 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FAM199X PF15814.5 PVD33163.1 - 8e-15 54.7 15.0 2.1e-14 53.3 0.9 3.1 1 1 2 3 3 3 2 Protein family FAM199X Av_adeno_fibre PF06536.11 PVD33164.1 - 0.0019 18.0 16.4 4.6 7.2 2.7 4.7 1 1 1 2 2 2 1 Avian adenovirus fibre, N-terminal DDT PF02791.17 PVD33164.1 - 0.011 16.0 0.0 2.4 8.5 0.0 2.8 1 1 1 2 2 2 0 DDT domain Suppressor_P21 PF11479.8 PVD33164.1 - 0.34 11.1 4.8 2.6 8.3 0.2 2.6 1 1 2 3 3 3 0 RNA silencing suppressor P21 C-terminal domain MetOD2 PF18548.1 PVD33164.1 - 1.4 9.1 4.0 9 6.5 0.2 2.7 1 1 2 3 3 3 0 Metanogen output domain 2 DUF775 PF05603.12 PVD33167.1 - 6.5e-52 176.0 1.1 1.1e-51 175.2 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MFS_1 PF07690.16 PVD33168.1 - 2.1e-18 66.4 14.9 1.1e-17 64.0 6.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily T-box PF00907.22 PVD33170.1 - 0.31 11.3 3.0 0.65 10.2 2.4 1.5 1 1 1 2 2 2 0 T-box DUF268 PF03269.14 PVD33172.1 - 0.13 12.1 8.8 54 3.6 1.3 4.8 1 1 4 5 5 5 0 Caenorhabditis protein of unknown function, DUF268 Sporozoite_P67 PF05642.11 PVD33173.1 - 0.56 8.2 7.3 0.58 8.2 7.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 PVD33173.1 - 0.74 8.0 19.5 0.75 7.9 19.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 PVD33173.1 - 1.1 9.3 31.9 0.063 13.3 20.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 PVD33173.1 - 6.7 4.6 9.2 7.4 4.4 9.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ets PF00178.22 PVD33174.1 - 3.6e-25 88.2 0.2 6e-25 87.5 0.2 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 PVD33174.1 - 2.1e-09 37.2 0.0 7.8e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.22 PVD33176.1 - 5.1e-23 81.3 0.1 1.1e-22 80.3 0.1 1.5 1 0 0 1 1 1 1 Ets-domain KCNQ2_u3 PF16642.5 PVD33176.1 - 0.026 15.5 0.6 0.09 13.8 0.6 1.9 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Scm3 PF10384.9 PVD33177.1 - 5.6e-05 22.8 7.3 16 5.3 0.1 5.3 3 3 2 5 5 5 5 Centromere protein Scm3 HEPN_Apea PF18739.1 PVD33177.1 - 0.014 15.9 0.6 7.1 7.1 0.1 3.2 1 1 2 3 3 3 0 Apea-like HEPN SNAP PF14938.6 PVD33177.1 - 0.33 10.3 0.4 5 6.4 0.2 1.9 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP DUF2173 PF09941.9 PVD33177.1 - 0.35 11.2 1.4 52 4.2 0.3 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2173) SAM_PNT PF02198.16 PVD33178.1 - 1.8e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CAP_N PF01213.19 PVD33179.1 - 1 8.8 3.9 1.2 8.5 3.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Silic_transp PF03842.13 PVD33180.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter Pkinase PF00069.25 PVD33181.1 - 3e-18 66.1 0.0 4.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33181.1 - 1e-09 38.1 0.0 3.5e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 PVD33181.1 - 0.18 12.1 4.2 4.5 7.8 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat MFS_1 PF07690.16 PVD33182.1 - 3.3e-05 23.0 0.0 5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 PVD33183.1 - 3.7 6.4 16.2 37 3.1 14.8 2.6 2 1 0 2 2 2 0 Major Facilitator Superfamily UPF0444 PF15475.6 PVD33186.1 - 6.9e-06 26.2 6.1 6.9e-06 26.2 6.1 2.2 2 1 0 2 2 2 1 Transmembrane protein C12orf23, UPF0444 FAM104 PF15434.6 PVD33186.1 - 0.03 14.9 5.9 0.04 14.5 5.9 1.1 1 0 0 1 1 1 0 Family 104 SR-25 PF10500.9 PVD33186.1 - 0.2 11.2 14.0 0.31 10.6 14.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 PVD33186.1 - 0.23 11.3 6.7 0.29 11.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Shisa PF13908.6 PVD33186.1 - 0.45 10.7 2.5 0.56 10.4 2.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Retinal PF15449.6 PVD33186.1 - 0.45 8.2 10.3 0.57 7.9 10.3 1.0 1 0 0 1 1 1 0 Retinal protein CCDC106 PF15794.5 PVD33186.1 - 3.6 7.2 8.1 4.4 6.9 8.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SNO PF01174.19 PVD33187.1 - 8.5e-46 156.2 0.0 9.8e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 PVD33187.1 - 3.4e-07 30.1 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SOR_SNZ PF01680.17 PVD33189.1 - 5.9e-110 365.9 3.7 9.2e-110 365.3 3.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 PVD33189.1 - 4.9e-09 35.9 2.4 1.8e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 PVD33189.1 - 0.00041 20.4 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Milton PF12448.8 PVD33189.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinesin associated protein NMO PF03060.15 PVD33189.1 - 0.59 9.5 6.5 0.21 10.9 0.9 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase PAN_1 PF00024.26 PVD33190.1 - 1.1e-06 28.5 9.8 9.2e-06 25.5 0.9 2.9 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PVD33190.1 - 0.00038 20.3 2.5 0.00038 20.3 2.5 3.7 3 1 0 3 3 3 2 PAN domain EB PF01683.18 PVD33190.1 - 0.014 15.7 11.6 0.014 15.7 11.6 2.8 2 1 0 2 2 2 0 EB module PAN_3 PF08277.12 PVD33190.1 - 0.045 13.6 1.2 0.045 13.6 1.2 3.3 3 0 0 3 3 3 0 PAN-like domain Arm PF00514.23 PVD33191.1 - 4.2e-29 99.7 9.2 3.7e-09 36.3 0.2 6.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD33191.1 - 3.1e-07 30.7 0.4 0.022 15.1 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 PVD33191.1 - 0.0002 21.3 2.7 0.31 11.4 0.3 4.2 4 0 0 4 4 4 1 HEAT repeat Arm_2 PF04826.13 PVD33191.1 - 0.00038 20.0 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 PVD33191.1 - 0.0069 15.0 0.5 1.4 7.4 0.0 2.5 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 PVD33191.1 - 0.019 15.5 3.1 9.1 6.9 0.2 4.8 5 0 0 5 5 5 0 HEAT-like repeat DNA_methylase PF00145.17 PVD33192.1 - 7e-30 104.5 0.0 8.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 PVD33192.1 - 0.024 14.2 0.0 0.079 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 PVD33192.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 PVD33193.1 - 9.3e-65 218.6 0.0 1.3e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33193.1 - 1e-45 156.0 0.3 6.2e-45 153.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD33193.1 - 0.00054 19.4 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD33193.1 - 0.009 16.0 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Vinculin PF01044.19 PVD33194.1 - 0 1234.6 29.3 0 1234.4 29.3 1.0 1 0 0 1 1 1 1 Vinculin family DUF2935 PF11155.8 PVD33194.1 - 0.2 12.0 1.6 73 3.7 0.3 4.4 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) Dynactin_p22 PF07426.11 PVD33194.1 - 1.4 8.7 8.6 1.3 8.9 0.5 4.0 3 0 0 3 3 3 0 Dynactin subunit p22 Gp-FAR-1 PF05823.12 PVD33194.1 - 4.5 7.6 11.0 0.25 11.7 0.7 4.1 5 1 0 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Occludin_ELL PF07303.13 PVD33194.1 - 4.7 8.0 10.6 97 3.8 0.0 5.1 5 1 1 6 6 6 0 Occludin homology domain SNARE_assoc PF09335.11 PVD33195.1 - 1.6e-20 73.8 6.1 1.6e-20 73.8 6.1 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4407 PF14362.6 PVD33195.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0016 PF01169.19 PVD33195.1 - 0.034 14.5 4.8 4.4 7.7 1.6 3.0 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 Gemini_mov PF01708.16 PVD33195.1 - 0.13 12.0 0.8 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein TTL PF03133.15 PVD33196.1 - 5.2e-110 367.2 0.0 7.1e-110 366.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PVD33196.1 - 2.7e-06 26.9 0.0 0.00044 19.6 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PVD33196.1 - 0.00095 18.5 0.0 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Filament PF00038.21 PVD33197.1 - 3.3e-18 66.3 56.3 9.7e-13 48.4 36.6 2.5 1 1 1 2 2 2 2 Intermediate filament protein LTD PF00932.19 PVD33197.1 - 4.6e-16 59.2 0.2 1.3e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Lamin Tail Domain TPR_MLP1_2 PF07926.12 PVD33197.1 - 0.0001 22.4 14.3 0.0001 22.4 14.3 4.3 1 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 PVD33197.1 - 0.4 10.0 43.2 0.017 14.5 9.9 2.9 1 1 1 2 2 2 0 Rabaptin-like protein Bacillus_HBL PF05791.11 PVD33197.1 - 1.2 9.0 28.4 3 7.7 2.3 3.6 1 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PTH2 PF01981.16 PVD33197.1 - 1.9 8.8 5.6 8.5 6.7 0.6 2.7 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 PI_PP_I PF18363.1 PVD33197.1 - 2.6 8.3 7.3 0.86 9.8 0.5 2.8 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain zf-C3HC4_3 PF13920.6 PVD33198.1 - 1e-09 38.1 11.4 1.9e-09 37.2 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD33198.1 - 9.7e-09 35.4 13.2 2.2e-08 34.3 13.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PVD33198.1 - 1.3e-07 31.3 13.1 3.3e-07 30.1 13.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD33198.1 - 5.5e-07 29.3 11.4 1.4e-06 28.1 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD33198.1 - 6.4e-07 29.1 9.6 6.4e-07 29.1 9.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PVD33198.1 - 3.4e-06 27.3 8.1 9.4e-06 25.8 8.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD33198.1 - 7.3e-06 25.9 7.3 1.6e-05 24.8 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD33198.1 - 0.00012 21.9 12.0 0.0004 20.3 11.8 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD33198.1 - 0.00029 20.9 10.0 0.00029 20.9 10.0 2.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 PVD33198.1 - 0.0038 17.3 5.0 0.011 15.8 5.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1091 PF06477.13 PVD33198.1 - 0.065 13.7 0.0 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) zf-RING_4 PF14570.6 PVD33198.1 - 0.78 9.6 11.2 3.7 7.4 11.1 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RA PF00788.23 PVD33199.1 - 3.4e-07 30.8 0.0 5.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF5082 PF16888.5 PVD33200.1 - 0.0066 16.7 4.4 0.0066 16.7 4.4 4.4 4 1 1 5 5 5 2 Domain of unknown function (DUF5082) Elf1 PF05129.13 PVD33200.1 - 0.078 13.0 0.8 0.19 11.8 0.8 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ZnuA PF01297.17 PVD33200.1 - 0.79 9.1 3.4 0.48 9.8 0.7 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic zf-C2H2_aberr PF17017.5 PVD33200.1 - 1.7 8.7 5.0 4.6 7.3 1.5 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger DUF1515 PF07439.11 PVD33200.1 - 2.1 8.4 7.5 0.99 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TMPIT PF07851.13 PVD33200.1 - 3.2 6.9 18.4 16 4.6 0.5 3.0 2 1 0 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 PVD33200.1 - 9.3 6.8 42.0 22 5.6 24.6 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Troponin PF00992.20 PVD33201.1 - 1.7e-09 38.1 14.0 1.7e-09 38.1 14.0 2.2 1 1 1 2 2 2 1 Troponin Kinesin PF00225.23 PVD33203.1 - 4.9e-73 245.9 2.1 4.9e-73 245.9 2.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain BHD_2 PF10404.9 PVD33203.1 - 0.013 16.4 0.8 0.013 16.4 0.8 2.5 2 1 0 2 2 2 0 Rad4 beta-hairpin domain 2 Kinesin_assoc PF16183.5 PVD33203.1 - 1.5 9.0 20.4 1.6 8.9 16.7 2.7 2 1 0 2 2 2 0 Kinesin-associated Exo_endo_phos_2 PF14529.6 PVD33204.1 - 1e-10 41.5 0.1 3.5e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF4371 PF14291.6 PVD33204.1 - 0.0027 17.4 0.3 0.0049 16.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) HSP20 PF00011.21 PVD33205.1 - 5.4e-10 39.3 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 PVD33206.1 - 9.8e-07 28.9 0.2 1.7e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 PVD33207.1 - 1.1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD33207.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Cupredoxin_1 PF13473.6 PVD33207.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupredoxin-like domain 7tm_1 PF00001.21 PVD33208.1 - 1.2e-05 24.8 7.5 0.011 15.0 0.1 2.5 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) NAP PF00956.18 PVD33210.1 - 6.4e-105 350.2 7.8 1.3e-104 349.2 7.8 1.5 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RVT_1 PF00078.27 PVD33212.1 - 1.2e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_5 PF12688.7 PVD33212.1 - 0.025 14.8 0.1 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Tetratrico peptide repeat Cation_efflux PF01545.21 PVD33213.1 - 2.8e-51 174.1 12.2 3.5e-51 173.8 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family Tetraspanin PF00335.20 PVD33215.1 - 3e-50 171.1 7.3 3e-50 171.1 7.3 1.5 2 0 0 2 2 2 1 Tetraspanin family PCRF PF03462.18 PVD33215.1 - 8.6e-47 159.5 0.5 8.6e-47 159.5 0.5 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 PVD33215.1 - 1.1e-37 128.6 5.6 1.9e-37 127.7 5.6 1.4 1 0 0 1 1 1 1 RF-1 domain RGS-like PF09128.11 PVD33215.1 - 0.13 12.0 1.0 0.27 10.9 1.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF2975 PF11188.8 PVD33215.1 - 7.7 6.4 7.0 1.6 8.6 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) GPS PF01825.21 PVD33216.1 - 3.6e-06 27.4 2.6 9.8e-06 26.0 2.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF1280 PF06918.14 PVD33217.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF4562 PF15123.6 PVD33220.1 - 3.9e-15 55.8 0.0 5.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) Skp1_POZ PF03931.15 PVD33221.1 - 1.3e-29 102.1 0.7 3.1e-29 101.0 0.4 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 PVD33221.1 - 5.5e-29 100.0 0.6 5.5e-29 100.0 0.6 2.0 2 0 0 2 2 2 1 Skp1 family, dimerisation domain BTB PF00651.31 PVD33221.1 - 0.11 12.7 0.0 1.5 9.1 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain PhosphMutase PF10143.9 PVD33222.1 - 0.063 13.1 5.2 0.096 12.6 5.2 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Homeodomain PF00046.29 PVD33224.1 - 4.6e-21 74.4 2.9 9.3e-21 73.4 2.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD33224.1 - 0.0082 16.0 0.1 0.026 14.4 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF2986 PF11661.8 PVD33224.1 - 0.059 13.9 0.6 0.059 13.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) YdaS_antitoxin PF15943.5 PVD33224.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT FXa_inhibition PF14670.6 PVD33225.1 - 2.3e-52 174.9 177.2 1.3e-10 41.4 10.8 12.1 13 1 0 13 13 13 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD33225.1 - 9.2e-39 131.0 81.5 7.6e-09 35.3 1.0 12.0 11 0 0 11 11 11 7 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 PVD33225.1 - 3.2e-30 103.7 39.1 3.3e-13 49.2 7.1 6.0 6 1 1 7 7 7 3 Putative ephrin-receptor like EGF_CA PF07645.15 PVD33225.1 - 5.8e-25 87.2 164.9 6.4e-08 32.7 7.6 12.5 12 1 0 13 13 13 6 Calcium-binding EGF domain CUB PF00431.20 PVD33225.1 - 7.9e-20 71.2 0.1 5.3e-19 68.6 0.0 2.3 2 0 0 2 2 2 1 CUB domain EGF PF00008.27 PVD33225.1 - 8e-20 70.8 115.9 0.00053 20.2 7.4 9.9 8 0 0 8 8 8 8 EGF-like domain EGF_3 PF12947.7 PVD33225.1 - 8e-19 67.6 138.1 5e-08 33.0 11.5 10.1 10 0 0 10 10 10 7 EGF domain hEGF PF12661.7 PVD33225.1 - 7.4e-10 39.1 97.2 0.0034 18.0 1.6 11.4 9 0 0 9 9 9 7 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 PVD33225.1 - 0.062 13.4 79.6 0.022 14.8 6.1 9.1 9 0 0 9 9 9 0 MSP1 EGF domain 1 Sulfatase PF00884.23 PVD33227.1 - 2e-48 165.4 0.7 2.8e-48 164.9 0.7 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD33227.1 - 0.0035 17.6 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 PVD33227.1 - 0.091 12.3 0.8 1.7 8.1 0.8 2.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_transf_10 PF00852.19 PVD33228.1 - 2.4e-61 206.5 0.7 4.3e-61 205.7 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD33228.1 - 1.2e-17 64.3 1.8 3.1e-17 63.0 0.8 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal COesterase PF00135.28 PVD33229.1 - 1.4e-66 225.5 0.0 3.3e-66 224.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD33229.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Utp14 PF04615.13 PVD33231.1 - 1.8 7.1 36.0 2.4 6.7 36.0 1.1 1 0 0 1 1 1 0 Utp14 protein TNFR_c6 PF00020.18 PVD33235.1 - 2.2e-08 34.4 3.7 3.7e-08 33.6 3.7 1.4 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region DUF1180 PF06679.12 PVD33235.1 - 0.0016 18.9 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Orf78 PF06024.12 PVD33235.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) NCD3G PF07562.14 PVD33235.1 - 0.019 14.9 2.8 0.034 14.1 2.8 1.4 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR TMEM132D_C PF15706.5 PVD33235.1 - 0.068 13.0 0.1 0.21 11.4 0.0 1.9 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DIM1 PF02966.16 PVD33236.1 - 3.6e-67 224.2 0.4 4.1e-67 224.0 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PVD33236.1 - 1.7e-05 24.7 0.1 2.2e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 PVD33236.1 - 0.0095 15.9 1.0 0.014 15.4 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PVD33236.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 PVD33236.1 - 0.035 14.4 0.3 0.056 13.8 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like BTD PF09270.10 PVD33237.1 - 4.9e-75 250.9 0.0 8.1e-75 250.2 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 PVD33237.1 - 1.2e-50 172.0 0.5 2.2e-50 171.2 0.5 1.4 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 PVD33237.1 - 0.00055 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain MINDY_DUB PF04424.13 PVD33238.1 - 6.1e-39 132.7 0.4 2.4e-38 130.8 0.1 2.2 2 0 0 2 2 2 1 MINDY deubiquitinase DUF3333 PF11812.8 PVD33238.1 - 2 8.6 4.4 4.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) CBM_14 PF01607.24 PVD33241.1 - 1.4e-14 54.0 25.5 5.1e-11 42.6 3.2 3.7 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Pep1_7 PF17232.2 PVD33241.1 - 0.016 15.6 0.3 0.034 14.6 0.3 1.4 1 0 0 1 1 1 0 Elicitor peptide 1-7 Med8 PF10232.9 PVD33241.1 - 0.048 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_VP91_N PF08475.10 PVD33241.1 - 0.17 11.5 2.7 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 Viral capsid protein 91 N-terminal DUF4611 PF15387.6 PVD33241.1 - 6.2 7.1 6.5 17 5.7 6.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) SIKE PF05769.11 PVD33242.1 - 4.3e-63 212.5 24.3 5.4e-63 212.2 24.3 1.1 1 0 0 1 1 1 1 SIKE family DUF4795 PF16043.5 PVD33242.1 - 0.012 15.2 2.2 0.012 15.2 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 PVD33242.1 - 0.083 11.8 22.3 0.22 10.4 17.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Desmo_N PF06771.11 PVD33242.1 - 0.15 12.5 0.3 14 6.1 0.1 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DUF3452 PF11934.8 PVD33242.1 - 0.45 10.1 2.8 1.6 8.3 2.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DASH_Dam1 PF08653.10 PVD33242.1 - 0.64 9.9 2.5 3 7.7 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dam1 Med30 PF11315.8 PVD33242.1 - 0.72 10.0 18.5 0.062 13.5 2.2 3.3 1 1 0 3 3 3 0 Mediator complex subunit 30 bZIP_1 PF00170.21 PVD33242.1 - 2 8.6 12.4 0.73 10.0 0.3 4.0 3 1 1 4 4 4 0 bZIP transcription factor ERM PF00769.19 PVD33242.1 - 2.4 7.9 25.3 0.14 11.9 15.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Sec20 PF03908.13 PVD33242.1 - 2.6 8.0 15.8 1 9.4 1.4 3.5 1 1 3 4 4 4 0 Sec20 IL2 PF00715.17 PVD33242.1 - 2.7 7.9 10.6 0.43 10.5 1.5 2.8 1 1 0 2 2 2 0 Interleukin 2 IL17 PF06083.11 PVD33243.1 - 2.2e-14 53.7 3.1 1.1e-13 51.4 3.1 1.8 1 1 0 1 1 1 1 Interleukin-17 adh_short PF00106.25 PVD33244.1 - 2e-42 144.9 0.0 2.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD33244.1 - 6e-27 94.7 0.0 8.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 PVD33244.1 - 4e-05 23.1 0.0 5.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 7TM_GPCR_Srw PF10324.9 PVD33246.1 - 1.5e-11 44.2 1.0 1.9e-11 43.8 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD33246.1 - 1.1e-10 41.2 3.6 1.7e-10 40.7 3.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD33246.1 - 9.6e-08 32.0 5.3 1.3e-07 31.5 5.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD33246.1 - 3.9e-07 29.7 1.4 5.7e-07 29.2 1.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.13 PVD33246.1 - 0.0016 17.6 1.8 0.0021 17.2 1.8 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Podoplanin PF05808.11 PVD33246.1 - 0.048 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Podoplanin 7TM_GPCR_Srbc PF10316.9 PVD33246.1 - 0.087 12.3 6.1 0.14 11.7 6.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srz PF10325.9 PVD33246.1 - 0.2 11.0 3.3 0.087 12.1 0.3 1.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz RUN PF02759.19 PVD33248.1 - 5e-29 101.0 0.0 1e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 RUN domain Mob1_phocein PF03637.17 PVD33249.1 - 4.2e-80 267.7 0.1 5e-80 267.4 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Syja_N PF02383.18 PVD33250.1 - 9.5e-53 179.6 1.0 2e-52 178.5 0.3 1.8 2 0 0 2 2 2 1 SacI homology domain DUF1866 PF08952.11 PVD33250.1 - 5.3e-33 113.9 0.2 8.7e-33 113.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 PVD33250.1 - 1.5e-14 54.1 0.1 2.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nup35_RRM PF05172.13 PVD33250.1 - 0.2 11.6 0.4 2.4 8.2 0.3 2.7 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif G-patch PF01585.23 PVD33251.1 - 2.4e-13 49.7 0.4 6.5e-13 48.4 0.4 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD33251.1 - 2.6e-05 24.2 0.4 2.6e-05 24.2 0.4 3.0 4 0 0 4 4 4 1 G-patch domain Pkinase PF00069.25 PVD33252.1 - 7e-71 238.7 0.1 1.4e-70 237.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 PVD33252.1 - 4.7e-44 148.4 0.7 2.9e-22 78.6 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 PVD33252.1 - 1.3e-37 129.5 0.0 2.5e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-met PF12874.7 PVD33252.1 - 7.9e-32 108.7 68.8 5.3e-05 23.5 0.3 10.5 12 0 0 12 12 10 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD33252.1 - 4.8e-16 58.6 56.7 0.0013 18.9 1.1 11.7 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding Ada3 PF10198.9 PVD33252.1 - 8.6e-15 55.0 12.6 8.6e-15 55.0 12.6 3.1 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Helicase_C PF00271.31 PVD33252.1 - 2.5e-13 50.3 1.6 4.4e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Kinase-like PF14531.6 PVD33252.1 - 2.8e-08 33.4 0.0 3.3e-06 26.7 0.0 2.4 1 1 0 2 2 2 1 Kinase-like zf-C2H2_2 PF12756.7 PVD33252.1 - 1.7e-07 31.5 63.3 0.22 11.8 3.0 11.2 8 3 3 11 11 10 5 C2H2 type zinc-finger (2 copies) ResIII PF04851.15 PVD33252.1 - 1.7e-07 31.4 0.0 5.2e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD33252.1 - 4.6e-07 29.8 0.0 5.8e-06 26.2 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Pkinase_fungal PF17667.1 PVD33252.1 - 7.8e-06 24.9 0.0 7.8e-06 24.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Vps39_2 PF10367.9 PVD33252.1 - 0.0088 16.5 1.7 0.0088 16.5 1.7 4.0 5 0 0 5 5 4 1 Vacuolar sorting protein 39 domain 2 PI-PLC-X PF00388.19 PVD33253.1 - 2.4e-63 212.1 0.0 8.9e-63 210.2 0.0 2.0 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PVD33253.1 - 7.7e-33 113.3 0.0 1.6e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 PVD33253.1 - 2.4e-15 56.8 0.0 6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 PVD33253.1 - 2.2e-11 44.0 0.0 5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain TEP1_N PF05386.11 PVD33253.1 - 0.14 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 TEP1 N-terminal domain MFAP1 PF06991.11 PVD33255.1 - 2.9e-76 256.1 31.3 2.9e-76 256.1 31.3 3.1 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing Pkinase PF00069.25 PVD33256.1 - 2.8e-50 171.1 0.0 3.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33256.1 - 1.4e-26 93.4 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD33256.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 PVD33256.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase CBM_14 PF01607.24 PVD33257.1 - 0.047 13.8 1.1 0.3 11.3 0.3 2.5 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Tsc35 PF15079.6 PVD33257.1 - 0.28 10.7 0.7 0.4 10.2 0.7 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 DUF1772 PF08592.11 PVD33258.1 - 0.012 16.0 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Ank_2 PF12796.7 PVD33260.1 - 8.4e-49 164.1 3.2 5.7e-13 49.3 0.2 8.0 6 1 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33260.1 - 7.4e-41 138.0 10.7 9.4e-10 38.8 0.3 11.8 7 1 5 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33260.1 - 2.5e-30 104.1 15.8 5.5e-08 32.9 0.9 9.2 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33260.1 - 7.8e-26 87.3 14.7 4.4e-05 23.5 0.1 13.0 16 0 0 16 16 16 4 Ankyrin repeat Ank PF00023.30 PVD33260.1 - 1.1e-22 79.4 26.3 1.8e-05 25.0 0.8 12.5 15 0 0 15 15 15 5 Ankyrin repeat SOCS_box PF07525.16 PVD33260.1 - 2e-09 37.6 0.8 6.1e-09 36.1 0.8 1.8 1 0 0 1 1 1 1 SOCS box NERD PF08378.11 PVD33261.1 - 0.059 13.8 0.0 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 Nuclease-related domain ADAM_CR_2 PF17771.1 PVD33262.1 - 7.5e-33 112.9 21.5 5.1e-18 65.3 6.3 5.6 5 0 0 5 5 5 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 PVD33262.1 - 2.6e-13 50.5 1.7 3.4e-12 46.9 0.4 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD33262.1 - 5.4e-12 46.3 0.1 2.8e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD33262.1 - 4.4e-11 43.1 7.0 3.4e-10 40.2 0.2 3.1 3 1 1 4 4 4 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD33262.1 - 4e-10 39.7 0.2 8.8e-10 38.6 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD33262.1 - 2.8e-09 37.2 2.4 8.5e-09 35.6 0.4 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Sld7_C PF18596.1 PVD33262.1 - 0.065 13.4 0.0 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Sld7 C-terminal domain Pep_M12B_propep PF01562.19 PVD33262.1 - 0.094 12.9 0.6 6 7.1 0.1 2.7 2 0 0 2 2 2 0 Reprolysin family propeptide ADAM_CR_2 PF17771.1 PVD33263.1 - 8.8e-17 61.4 6.1 8.8e-17 61.4 6.1 4.4 5 1 0 5 5 5 1 ADAM cysteine-rich domain zf-CCCH_4 PF18044.1 PVD33263.1 - 5 7.0 9.5 72 3.3 0.3 5.0 4 0 0 4 4 4 0 CCCH-type zinc finger HORMA PF02301.18 PVD33264.1 - 4.7e-55 186.4 0.1 4.7e-55 186.4 0.1 2.0 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 PVD33264.1 - 4.7e-06 26.4 11.7 9.9e-06 25.4 11.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PVD33264.1 - 0.056 13.0 6.4 0.11 12.1 6.4 1.5 1 0 0 1 1 1 0 PHD-finger EVI2A PF05399.11 PVD33264.1 - 0.25 10.9 5.0 0.086 12.4 2.3 1.5 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) PolC_DP2 PF03833.13 PVD33264.1 - 1.9 6.3 6.1 2.7 5.7 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Apt1 PF10351.9 PVD33266.1 - 1.7 7.4 10.4 1.8 7.3 10.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 PVD33266.1 - 9 4.9 12.1 11 4.6 12.1 1.1 1 0 0 1 1 1 0 Presenilin U1snRNP70_N PF12220.8 PVD33267.1 - 7.3e-08 32.9 3.6 1.4e-07 32.0 3.6 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 PVD33267.1 - 0.0047 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans PF00520.31 PVD33268.1 - 4.4e-50 170.2 9.7 5.7e-50 169.8 9.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD33268.1 - 7.7e-28 96.7 0.1 1.4e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD33268.1 - 1.6e-13 50.4 4.7 1.6e-13 50.4 4.7 2.6 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 PVD33268.1 - 0.01 14.5 0.9 0.01 14.5 0.9 2.0 2 1 1 3 3 3 0 Polycystin cation channel BTB_3 PF16017.5 PVD33268.1 - 0.037 14.1 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF5056 PF16479.5 PVD33268.1 - 0.09 13.0 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Sigma_reg_N PF13800.6 PVD33268.1 - 0.15 12.3 4.8 5.4 7.4 0.0 3.8 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF423 PF04241.15 PVD33268.1 - 0.36 11.1 1.1 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF423) YrhC PF14143.6 PVD33268.1 - 1.4 9.1 6.8 2.1 8.5 0.1 3.0 3 0 0 3 3 3 0 YrhC-like protein MFS_1 PF07690.16 PVD33269.1 - 7.5e-15 54.7 58.6 2.1e-08 33.5 17.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD33269.1 - 0.0003 19.8 1.1 0.0003 19.8 1.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3185 PF11381.8 PVD33269.1 - 4.9 7.2 11.2 3.4 7.8 0.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) TPP_enzyme_N PF02776.18 PVD33270.1 - 6e-50 169.2 1.5 1.2e-49 168.3 0.9 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 PVD33270.1 - 8e-29 100.4 0.0 6e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 PVD33270.1 - 6e-19 68.1 0.3 3.4e-18 65.7 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.23 PVD33270.1 - 0.075 12.8 0.5 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain Patatin PF01734.22 PVD33273.1 - 3e-13 50.4 0.1 1.4e-12 48.2 0.0 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase MoeA_C PF03454.15 PVD33273.1 - 0.11 12.7 0.4 0.3 11.3 0.4 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) DUF687 PF05095.12 PVD33274.1 - 0.083 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) SET PF00856.28 PVD33275.1 - 8.3e-26 91.4 7.5 6.8e-25 88.4 1.1 3.8 3 1 0 3 3 3 1 SET domain TUDOR_5 PF18359.1 PVD33275.1 - 7.3e-25 86.4 0.3 1.3e-20 72.8 0.1 2.5 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Pre-SET PF05033.16 PVD33275.1 - 9.4e-17 61.6 12.1 3.3e-16 59.9 12.1 2.0 1 0 0 1 1 1 1 Pre-SET motif MBD PF01429.19 PVD33275.1 - 4e-07 29.7 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain DUF5604 PF18300.1 PVD33275.1 - 7.7e-07 29.0 1.6 2.5e-06 27.3 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5604) SHE3 PF17078.5 PVD33275.1 - 0.0073 16.1 4.0 0.025 14.3 4.0 1.9 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF1325 PF07039.11 PVD33275.1 - 0.019 15.0 0.0 0.33 11.0 0.0 2.8 1 1 1 2 2 2 0 SGF29 tudor-like domain Tudor_3 PF18115.1 PVD33275.1 - 0.034 14.0 0.3 10 6.1 0.1 2.7 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain MoCF_biosynth PF00994.24 PVD33276.1 - 4.5e-31 107.5 0.0 7.5e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 PVD33276.1 - 8.2e-15 55.3 0.0 1.6e-06 28.3 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Imm70 PF15601.6 PVD33276.1 - 0.064 12.8 0.1 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 70 HIM1 PF08732.10 PVD33276.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 HIM1 FYVE PF01363.21 PVD33277.1 - 1.6e-18 66.6 10.4 3.3e-18 65.6 9.7 1.8 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 PVD33277.1 - 2.5e-09 37.6 0.3 1.2e-08 35.4 0.1 2.0 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 PVD33277.1 - 0.003 17.8 5.8 0.005 17.0 5.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 PVD33277.1 - 0.004 17.1 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 PH domain Myb_DNA-bind_4 PF13837.6 PVD33278.1 - 4.4e-18 65.5 2.5 1.2e-17 64.0 2.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD33278.1 - 2e-07 31.2 2.6 2e-07 31.2 2.6 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 PVD33278.1 - 0.0022 18.2 2.0 0.0067 16.6 2.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD33278.1 - 0.0039 17.2 3.7 0.0046 17.0 0.5 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 PVD33278.1 - 0.01 16.8 0.8 0.01 16.8 0.8 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5094 PF17015.5 PVD33278.1 - 0.089 12.9 2.9 0.17 11.9 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF4485 PF14846.6 PVD33278.1 - 0.82 9.8 6.5 39 4.4 6.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4485) UQ_con PF00179.26 PVD33279.1 - 3.2e-42 143.5 0.0 4.3e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PVD33279.1 - 0.016 15.5 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 PVD33279.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF498 PF04430.14 PVD33279.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Ribosomal_S13_N PF08069.12 PVD33282.1 - 7.9e-16 57.9 0.1 1.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 PVD33282.1 - 1e-09 38.5 0.5 1.8e-09 37.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3140 PF11338.8 PVD33282.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) DUF3827 PF12877.7 PVD33287.1 - 6.1e-05 21.6 0.0 8.3e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) CD34_antigen PF06365.12 PVD33287.1 - 0.0024 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF3377 PF11857.8 PVD33287.1 - 0.012 15.6 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 PVD33287.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4287 PF14117.6 PVD33287.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Pkinase PF00069.25 PVD33289.1 - 8.1e-40 136.8 0.0 6.9e-21 74.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33289.1 - 4.5e-17 62.2 0.0 6.9e-11 41.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_9 PF14580.6 PVD33290.1 - 1.4e-15 57.3 2.8 1.1e-11 44.6 1.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 PVD33290.1 - 9.5e-14 51.3 14.0 0.0005 20.4 0.0 4.6 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD33290.1 - 9.8e-11 41.3 9.8 1.5e-06 27.8 0.2 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 PVD33290.1 - 0.18 12.0 11.3 0.85 9.8 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeat V-ATPase_C PF03223.15 PVD33291.1 - 6.1e-162 539.2 0.2 6.9e-162 539.0 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C FliD_N PF02465.18 PVD33291.1 - 0.24 12.1 2.8 0.37 11.5 0.2 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ADK PF00406.22 PVD33292.1 - 1.4e-05 25.2 0.0 4.2e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 PVD33292.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 PVD33293.1 - 6.7e-60 201.5 0.0 7.4e-60 201.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PVD33293.1 - 3.1e-11 43.6 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD33293.1 - 1.2e-09 38.0 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PVD33293.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PVD33293.1 - 1.7e-08 34.0 0.2 3.2e-08 33.1 0.2 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 PVD33293.1 - 3.1e-08 33.3 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SpoOE-like PF09388.10 PVD33293.1 - 0.0075 16.1 0.9 0.013 15.4 0.9 1.4 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein Met_10 PF02475.16 PVD33294.1 - 1.6e-29 103.1 0.0 3.8e-29 101.8 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 PVD33294.1 - 1.7e-05 24.4 0.0 5.8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Trm5_N PF18093.1 PVD33294.1 - 0.00068 19.5 0.2 0.0014 18.5 0.2 1.5 1 0 0 1 1 1 1 tRNA methyltransferase 5 N-terminal domain Cons_hypoth95 PF03602.15 PVD33294.1 - 0.0038 16.9 0.1 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 PVD33294.1 - 0.053 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 PVD33294.1 - 0.073 12.4 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_25 PF13649.6 PVD33294.1 - 0.097 13.4 0.0 0.36 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 PVD33294.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Reprolysin_5 PF13688.6 PVD33295.1 - 1.2e-08 35.4 4.9 3.3e-08 33.9 4.9 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD33295.1 - 2.5e-08 34.5 0.1 1.1e-07 32.4 0.0 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD33295.1 - 3.8e-07 30.2 0.4 1.3e-06 28.5 0.4 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 PVD33295.1 - 7.6e-06 26.0 0.2 1.9e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD33295.1 - 0.00019 21.1 0.2 0.00041 20.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 PVD33296.1 - 2.1e-18 66.6 9.2 2.1e-18 66.6 9.2 3.3 3 1 0 3 3 3 1 ADAM cysteine-rich domain DUF3827 PF12877.7 PVD33299.1 - 4.9e-19 68.2 36.2 1.4e-17 63.4 3.3 5.1 4 1 1 5 5 5 3 Domain of unknown function (DUF3827) Amnionless PF14828.6 PVD33299.1 - 0.019 13.8 0.4 0.05 12.4 0.4 1.6 1 0 0 1 1 1 0 Amnionless LST1 PF05083.13 PVD33299.1 - 0.032 14.5 0.1 0.093 13.0 0.1 1.8 1 0 0 1 1 1 0 LST-1 protein EphA2_TM PF14575.6 PVD33299.1 - 0.047 14.6 2.5 0.049 14.5 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PVD33299.1 - 0.33 11.0 0.9 0.72 10.0 0.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF829 PF05705.14 PVD33300.1 - 1.4e-38 133.1 0.7 3.3e-38 132.0 0.7 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Hydrolase_4 PF12146.8 PVD33300.1 - 0.0026 17.1 0.0 0.069 12.4 0.0 2.6 2 1 1 3 3 3 1 Serine aminopeptidase, S33 T3RM_EcoP15I_C PF18273.1 PVD33300.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain Abhydrolase_2 PF02230.16 PVD33300.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF829 PF05705.14 PVD33301.1 - 1.6e-45 155.9 0.1 2.6e-45 155.2 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RRM_1 PF00076.22 PVD33302.1 - 1.3e-18 66.5 0.0 1.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD33302.1 - 0.0023 17.8 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 PVD33302.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD33302.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif DbpA PF03880.15 PVD33302.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain SET_assoc PF11767.8 PVD33302.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 PVD33303.1 - 3.1e-19 68.6 0.0 4.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD33303.1 - 0.0007 19.2 0.0 0.00083 18.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 PVD33303.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_occluded PF16842.5 PVD33303.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 PVD33303.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 PVD33303.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 PVD33303.1 - 0.3 10.8 3.1 1.5 8.6 3.1 2.0 1 1 0 1 1 1 0 Ribonuclease B OB domain CD225 PF04505.12 PVD33304.1 - 8.1e-14 51.5 0.6 1.1e-13 51.1 0.6 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4199 PF13858.6 PVD33304.1 - 0.009 16.4 1.1 0.011 16.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF5083 PF16890.5 PVD33304.1 - 0.023 14.4 0.7 0.031 14.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) DUF3671 PF12420.8 PVD33304.1 - 0.029 14.4 0.9 0.039 14.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function ABC2_membrane_4 PF12730.7 PVD33304.1 - 0.04 13.9 1.0 0.055 13.4 1.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4064 PF13273.6 PVD33304.1 - 0.066 13.5 0.9 0.1 12.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Synaptobrevin PF00957.21 PVD33304.1 - 0.15 11.9 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF5316 PF17247.2 PVD33304.1 - 0.25 11.4 2.4 0.91 9.6 0.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5316) DUF4190 PF13828.6 PVD33304.1 - 0.63 9.8 5.3 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Pep3_Vps18 PF05131.14 PVD33305.1 - 1.1e-33 116.1 0.0 2.5e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 PVD33305.1 - 1.2e-10 41.4 18.9 1e-09 38.4 2.4 4.1 3 1 1 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 PVD33305.1 - 1.4e-07 31.9 0.3 3.3e-07 30.7 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 PVD33305.1 - 0.00031 21.0 0.6 0.00031 21.0 0.6 3.9 5 0 0 5 5 3 1 Ring finger domain zf-RING_11 PF17123.5 PVD33305.1 - 0.00043 20.0 2.7 0.00043 20.0 2.7 3.2 3 0 0 3 3 2 1 RING-like zinc finger zf-RING_5 PF14634.6 PVD33305.1 - 0.00081 19.3 0.4 0.00081 19.3 0.4 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD33305.1 - 0.001 18.9 1.6 0.001 18.9 1.6 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD33305.1 - 0.0073 16.3 0.8 0.0073 16.3 0.8 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD33305.1 - 0.018 15.3 0.4 0.018 15.3 0.4 3.1 4 0 0 4 4 3 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 PVD33305.1 - 0.021 14.5 0.4 0.021 14.5 0.4 2.8 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type DUF1664 PF07889.12 PVD33305.1 - 0.35 10.9 2.4 0.38 10.8 0.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 PVD33305.1 - 0.48 10.2 5.9 0.4 10.5 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 PVD33305.1 - 0.76 7.9 7.9 0.05 11.8 0.9 2.1 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil TPR_2 PF07719.17 PVD33305.1 - 1.3 9.3 5.7 78 3.8 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33305.1 - 1.7 9.0 6.8 20 5.7 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 PVD33305.1 - 4 7.4 10.2 0.12 12.2 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Occludin_ELL PF07303.13 PVD33305.1 - 7.1 7.4 8.1 7.1 7.4 0.1 3.6 4 1 0 4 4 3 0 Occludin homology domain zf-H2C2_5 PF13909.6 PVD33306.1 - 1.4e-06 27.9 15.9 2.1e-05 24.2 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 PVD33306.1 - 1e-05 25.7 25.6 0.01 16.3 0.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33306.1 - 0.00058 20.5 25.5 0.14 13.1 0.2 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD33306.1 - 0.0029 17.9 2.4 0.0029 17.9 2.4 2.8 3 0 0 3 3 2 1 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.15 PVD33306.1 - 0.026 14.4 1.4 0.026 14.4 1.4 2.8 2 1 1 3 3 3 0 Recombination endonuclease VII zf-MYST PF17772.1 PVD33306.1 - 0.041 13.5 1.3 6.3 6.5 0.3 2.5 1 1 1 2 2 2 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 PVD33306.1 - 0.066 13.7 15.2 0.69 10.5 0.8 4.7 5 0 0 5 5 5 0 Zinc-finger double domain OrsD PF12013.8 PVD33306.1 - 0.086 13.3 0.3 0.086 13.3 0.3 2.8 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met PF12874.7 PVD33306.1 - 0.098 13.1 0.1 0.098 13.1 0.1 5.2 5 0 0 5 5 4 0 Zinc-finger of C2H2 type YrbL-PhoP_reg PF10707.9 PVD33306.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Vps36-NZF-N PF16988.5 PVD33306.1 - 0.2 11.1 8.4 1.8 8.0 0.1 3.6 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 PVD33306.1 - 0.38 10.8 17.2 4.3 7.5 0.2 4.5 6 0 0 6 6 5 0 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 PVD33306.1 - 0.61 10.5 0.1 0.61 10.5 0.1 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-MIZ PF02891.20 PVD33306.1 - 0.71 9.7 9.0 0.81 9.5 2.5 3.0 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf_C2H2_ZHX PF18387.1 PVD33306.1 - 1.6 8.4 7.6 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain JmjC PF02373.22 PVD33307.1 - 5.9e-26 91.1 0.1 1.2e-25 90.1 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PVD33307.1 - 1.2e-17 64.5 0.4 3.1e-17 63.1 0.4 1.7 1 1 0 1 1 1 1 Cupin-like domain NAM-associated PF14303.6 PVD33307.1 - 2.9 8.6 12.0 6.8 7.4 12.0 1.7 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF913 PF06025.12 PVD33307.1 - 3.1 6.7 6.2 4.5 6.1 6.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 PVD33307.1 - 9.3 4.2 7.5 11 3.9 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 PVD33307.1 - 10 5.9 20.4 14 5.4 20.4 1.2 1 0 0 1 1 1 0 SPX domain SIX1_SD PF16878.5 PVD33308.1 - 2.1e-14 54.0 0.1 4.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeobox_KN PF05920.11 PVD33308.1 - 2.1e-12 46.7 0.2 5.1e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD33308.1 - 9.8e-09 34.9 0.6 2e-08 33.9 0.6 1.6 1 0 0 1 1 1 1 Homeodomain UQ_con PF00179.26 PVD33309.1 - 1.3e-38 131.8 0.1 3.8e-38 130.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme ATG101 PF07855.12 PVD33309.1 - 2e-24 86.3 0.0 3.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 101 PSS PF03034.15 PVD33310.1 - 8.5e-105 350.4 18.6 8.5e-105 350.4 18.6 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Na_H_Exchanger PF00999.21 PVD33311.1 - 8.6e-56 189.4 39.1 1.3e-55 188.7 39.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TMEM240 PF15207.6 PVD33311.1 - 0.088 12.5 0.7 17 5.0 0.2 2.7 2 0 0 2 2 2 0 TMEM240 family cNMP_binding PF00027.29 PVD33312.1 - 4.4e-14 52.3 0.1 1e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4780 PF16012.5 PVD33312.1 - 0.0071 15.8 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4780) MFS_1 PF07690.16 PVD33313.1 - 1.1e-26 93.7 39.2 8e-20 71.0 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PQQ_3 PF13570.6 PVD33313.1 - 0.38 11.3 3.4 4.5 7.9 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain Na_H_Exchanger PF00999.21 PVD33314.1 - 1.1e-14 54.0 30.6 1.1e-14 54.0 30.6 2.3 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 PVD33314.1 - 5.2e-10 39.3 0.0 1.4e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4735 PF15882.5 PVD33314.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) p450 PF00067.22 PVD33315.1 - 3.3e-82 276.7 0.0 3.7e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRAS PF15798.5 PVD33316.1 - 1.2e-13 51.7 0.2 1.2e-13 51.7 0.2 1.9 2 1 0 2 2 2 1 Proline-rich AKT1 substrate 1 DUF1057 PF06342.12 PVD33317.1 - 0.072 12.1 0.0 0.082 11.9 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 PVD33318.1 - 3.6e-06 26.1 0.3 4.6e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PVD33318.1 - 0.13 11.2 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 PVD33319.1 - 2.9e-21 75.5 0.0 5.2e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PVD33319.1 - 0.00014 21.0 0.0 0.00073 18.6 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase SDF PF00375.18 PVD33320.1 - 3.8e-77 259.9 30.0 4.9e-77 259.6 30.0 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FAM221 PF14753.6 PVD33321.1 - 2.2e-17 63.3 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Protein FAM221A/B Tnp_22_trimer PF17489.2 PVD33321.1 - 0.055 13.5 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain DUF4890 PF16231.5 PVD33321.1 - 0.094 13.2 0.1 0.15 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) FAM124 PF15067.6 PVD33323.1 - 2.7e-30 105.7 0.0 1.2e-21 77.4 0.0 2.1 1 1 1 2 2 2 2 FAM124 family RGP PF03214.13 PVD33323.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Laminin_EGF PF00053.24 PVD33325.1 - 0.0037 17.4 11.9 0.0037 17.4 11.9 8.4 2 2 6 8 8 8 3 Laminin EGF domain DEFB136 PF17333.2 PVD33325.1 - 0.93 9.5 57.1 0.11 12.5 2.0 6.4 6 1 0 6 6 6 0 Beta defensin 136 Gram_pos_anchor PF00746.21 PVD33326.1 - 0.093 12.7 0.3 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TMEM237 PF15383.6 PVD33328.1 - 1.7e-49 168.2 0.2 1.7e-49 168.2 0.2 1.4 2 0 0 2 2 2 1 Transmembrane protein 237 YqhR PF11085.8 PVD33328.1 - 0.014 15.3 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 Conserved membrane protein YqhR FtsX PF02687.21 PVD33328.1 - 2.4 8.7 6.9 9.7 6.7 0.1 2.4 2 1 0 2 2 2 0 FtsX-like permease family DUF5567 PF17722.1 PVD33329.1 - 6.1e-16 59.0 4.1 5e-13 49.5 0.1 2.3 2 1 0 2 2 2 2 Family of unknown function (DUF5567) LIM PF00412.22 PVD33330.1 - 2.5e-11 43.6 6.9 3.6e-11 43.1 6.9 1.2 1 0 0 1 1 1 1 LIM domain PHD_4 PF16866.5 PVD33330.1 - 0.011 15.8 2.1 0.018 15.1 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf_UBZ PF18439.1 PVD33330.1 - 0.013 15.1 5.1 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 PVD33330.1 - 0.033 14.4 6.8 0.049 13.9 6.8 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain C1_1 PF00130.22 PVD33330.1 - 0.044 13.7 7.2 0.082 12.8 7.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELFV_dehydrog PF00208.21 PVD33332.1 - 0.03 14.0 0.1 0.039 13.7 0.1 1.3 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApoM PF11032.8 PVD33335.1 - 0.046 13.4 0.3 0.071 12.8 0.3 1.3 1 0 0 1 1 1 0 ApoM domain Spem1 PF15670.5 PVD33337.1 - 0.08 12.5 0.6 0.11 12.0 0.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 RhoGEF PF00621.20 PVD33338.1 - 7.6e-45 153.4 3.7 7.6e-45 153.4 3.7 2.1 2 0 0 2 2 2 1 RhoGEF domain RhoGEF PF00621.20 PVD33339.1 - 1.9e-44 152.0 4.8 2.9e-44 151.5 4.8 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PVD33339.1 - 1.2e-05 25.8 0.0 2.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 PVD33340.1 - 1.6e-44 152.4 5.7 2.8e-44 151.5 5.7 1.4 1 0 0 1 1 1 1 RhoGEF domain 7tm_1 PF00001.21 PVD33341.1 - 3.2e-26 92.2 9.7 6e-26 91.3 9.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4381 PF14316.6 PVD33341.1 - 0.21 11.8 0.3 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Myc_target_1 PF15179.6 PVD33341.1 - 0.29 11.0 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Myc target protein 1 TMEM154 PF15102.6 PVD33341.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.4 3 0 0 3 3 3 0 TMEM154 protein family zf-RING_5 PF14634.6 PVD33343.1 - 0.0065 16.4 6.6 0.021 14.8 6.4 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD33343.1 - 0.0084 16.1 2.9 0.041 13.9 3.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD33343.1 - 0.012 15.9 4.5 0.012 15.9 4.5 1.8 1 1 0 1 1 1 0 Ring finger domain zf-RING_14 PF17978.1 PVD33343.1 - 0.021 15.2 2.6 0.063 13.7 2.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 PVD33343.1 - 0.48 10.3 8.5 0.31 10.9 5.1 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Myb_DNA-binding PF00249.31 PVD33344.1 - 1.2e-46 156.7 27.4 4.7e-18 65.1 2.4 4.0 4 0 0 4 4 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD33344.1 - 7.3e-38 128.6 12.0 2.3e-17 63.0 1.3 3.8 1 1 2 3 3 3 3 Myb-like DNA-binding domain Cmyb_C PF09316.10 PVD33344.1 - 2.4e-12 46.8 2.5 6.3e-12 45.5 2.5 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-bind_7 PF15963.5 PVD33344.1 - 5.5e-09 35.8 10.7 0.0011 18.8 0.5 4.7 2 1 2 4 4 4 4 Myb DNA-binding like SLIDE PF09111.10 PVD33344.1 - 2e-05 24.6 0.6 1.4 8.9 0.0 3.7 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 PVD33344.1 - 0.00077 19.6 3.6 2.2 8.5 0.0 3.6 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 PVD33344.1 - 0.035 14.3 0.0 11 6.3 0.0 3.3 3 0 0 3 3 3 0 Rap1 Myb domain Sigma70_r4_2 PF08281.12 PVD33344.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Rap1_C PF11626.8 PVD33344.1 - 0.054 13.6 11.8 0.91 9.6 0.9 4.1 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 PVD33344.1 - 0.066 13.6 11.7 11 6.4 0.4 4.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 PVD33344.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_9 PF13901.6 PVD33345.1 - 2e-64 217.4 30.9 1.1e-61 208.5 17.9 2.3 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 PVD33345.1 - 2.6e-06 27.2 13.4 2.6e-06 27.2 13.4 4.6 3 2 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ldl_recept_a PF00057.18 PVD33346.1 - 3e-13 49.7 27.3 8.7e-08 32.3 7.3 2.9 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A V-set PF07686.17 PVD33346.1 - 0.00027 21.1 0.0 0.0007 19.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD33346.1 - 0.039 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Syndecan PF01034.20 PVD33346.1 - 2 8.4 3.8 3.8 7.5 3.8 1.4 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.6 PVD33347.1 - 8.1e-11 42.1 8.1 4.9e-05 23.5 0.2 4.1 3 2 1 4 4 4 3 Tetratricopeptide repeat SET PF00856.28 PVD33347.1 - 1.1e-10 42.1 0.0 1.7e-09 38.3 0.0 2.7 1 1 1 2 2 2 1 SET domain TPR_2 PF07719.17 PVD33347.1 - 2.5e-07 30.3 2.7 0.31 11.3 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat zf-MYND PF01753.18 PVD33347.1 - 0.00015 21.8 7.7 0.00015 21.8 7.7 2.8 2 0 0 2 2 2 1 MYND finger TPR_10 PF13374.6 PVD33347.1 - 0.0023 17.7 7.9 0.18 11.7 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD33347.1 - 0.013 15.3 1.8 8.2 6.4 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 PVD33347.1 - 0.037 13.5 0.0 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.6 PVD33347.1 - 0.092 13.6 1.3 1.2 10.1 0.2 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 PVD33347.1 - 2.6 7.8 20.8 0.11 12.2 11.4 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PAN_1 PF00024.26 PVD33348.1 - 3.2e-07 30.2 5.7 8.9e-07 28.8 5.7 1.8 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD33348.1 - 0.92 9.5 7.0 0.16 11.9 2.3 2.2 2 0 0 2 2 2 0 PAN domain Ras PF00071.22 PVD33349.1 - 3e-38 131.0 0.3 3.8e-37 127.4 0.0 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PVD33349.1 - 2.9e-18 66.2 0.0 7.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD33349.1 - 3e-11 43.1 0.1 7.8e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD33349.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 PVD33349.1 - 0.00073 20.1 0.1 0.0068 17.0 0.0 2.5 2 0 0 2 2 2 1 TIR domain DUF4407 PF14362.6 PVD33349.1 - 0.73 9.1 16.6 1.6 8.0 16.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 PVD33349.1 - 0.76 9.8 12.8 2.7 8.0 9.0 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Selenoprotein_S PF06936.11 PVD33349.1 - 3.5 7.4 16.1 8.7 6.1 16.1 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) V_ATPase_I PF01496.19 PVD33349.1 - 9.2 4.0 16.3 16 3.3 16.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF-hand_7 PF13499.6 PVD33350.1 - 4.3e-18 65.5 7.0 9.5e-13 48.4 0.9 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD33350.1 - 3e-15 54.9 1.1 1.5e-07 30.6 0.5 2.3 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 PVD33350.1 - 4.1e-15 54.1 0.9 2.2e-07 29.9 0.5 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD33350.1 - 4e-14 51.3 0.4 3.8e-06 26.4 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD33350.1 - 2.3e-07 30.6 1.9 3.3e-06 26.8 0.7 2.3 1 1 1 2 2 2 2 EF-hand domain pair MgtE_N PF03448.17 PVD33350.1 - 0.0021 18.6 0.5 0.008 16.8 0.5 1.9 1 1 0 1 1 1 1 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 PVD33350.1 - 0.0072 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD33350.1 - 0.0096 15.9 0.2 0.082 12.9 0.2 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PVD33350.1 - 0.014 15.3 1.1 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 EF hand p450 PF00067.22 PVD33356.1 - 4.4e-80 269.7 0.0 4.9e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L22 PF00237.19 PVD33356.1 - 0.12 12.7 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e PAP2 PF01569.21 PVD33358.1 - 6.1e-27 94.0 0.4 2.4e-26 92.1 0.4 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 PVD33358.1 - 6.3e-07 29.3 6.5 3e-06 27.0 5.9 2.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 PVD33358.1 - 0.00046 20.7 2.1 0.00046 20.7 2.1 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal MtrC PF04211.13 PVD33358.1 - 0.02 13.9 0.4 0.067 12.2 0.1 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C Gpr1_Fun34_YaaH PF01184.19 PVD33358.1 - 0.056 13.0 0.1 0.056 13.0 0.1 1.8 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Colicin_V PF02674.16 PVD33358.1 - 0.063 13.2 0.3 0.063 13.2 0.3 2.1 2 1 0 2 2 2 0 Colicin V production protein G6PD_C PF02781.16 PVD33359.1 - 6.8e-53 179.7 0.0 1.1e-45 156.1 0.0 2.1 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 PVD33359.1 - 1.2e-51 175.8 0.0 1.7e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 PVD33359.1 - 2.9e-30 106.2 0.0 4.8e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DNA_Packaging PF11053.8 PVD33361.1 - 0.018 14.9 0.7 4.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Terminase DNA packaging enzyme DUF1990 PF09348.10 PVD33361.1 - 0.26 11.3 2.6 0.14 12.2 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1990) CCER1 PF15482.6 PVD33361.1 - 3.3 7.6 17.0 0.41 10.5 0.9 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing glutamate-rich protein family 1 Shisa PF13908.6 PVD33361.1 - 9.6 6.4 14.6 0.29 11.4 0.8 2.7 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Tetraspanin PF00335.20 PVD33362.1 - 3.7e-35 121.7 4.1 5.2e-35 121.2 4.1 1.2 1 0 0 1 1 1 1 Tetraspanin family PsbN PF02468.15 PVD33362.1 - 6 6.8 5.9 1.4 8.9 0.9 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Sdh5 PF03937.16 PVD33363.1 - 2.3e-22 78.7 0.1 3.6e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase 2H-phosphodiest PF08975.10 PVD33363.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Abhydrolase_1 PF00561.20 PVD33364.1 - 1.8e-35 122.8 2.3 5e-21 75.5 0.2 4.8 3 1 1 4 4 4 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD33364.1 - 2.4e-31 110.1 0.3 2.4e-17 64.3 0.0 2.9 2 1 1 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD33364.1 - 2.5e-21 76.0 0.0 1.7e-11 43.9 0.0 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 PVD33364.1 - 3.6e-08 33.4 0.0 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 PGAP1-like protein Ndr PF03096.14 PVD33364.1 - 6.8e-06 25.0 0.0 0.1 11.3 0.0 3.1 2 2 0 2 2 2 2 Ndr family Abhydrolase_5 PF12695.7 PVD33364.1 - 6.1e-05 22.8 0.0 2.2 8.0 0.0 3.8 4 0 0 4 4 4 2 Alpha/beta hydrolase family DLH PF01738.18 PVD33364.1 - 0.0035 16.9 0.0 11 5.5 0.0 3.7 4 0 0 4 4 4 2 Dienelactone hydrolase family EHN PF06441.12 PVD33364.1 - 0.013 15.9 0.2 0.21 12.0 0.0 2.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF3663 PF12404.8 PVD33364.1 - 0.026 14.5 0.7 10 6.2 0.1 2.4 2 0 0 2 2 2 0 Peptidase Esterase PF00756.20 PVD33364.1 - 0.055 13.1 0.0 13 5.3 0.0 2.6 3 1 0 3 3 3 0 Putative esterase zf-nanos PF05741.13 PVD33364.1 - 0.3 11.3 1.4 19 5.6 0.0 2.7 3 0 0 3 3 3 0 Nanos RNA binding domain Abhydrolase_1 PF00561.20 PVD33365.1 - 7.9e-27 94.5 0.1 8.1e-26 91.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD33365.1 - 6e-25 89.1 0.0 7.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD33365.1 - 1.8e-17 63.4 0.0 4.6e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PVD33365.1 - 6.7e-07 28.3 0.0 4.9e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.13 PVD33365.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 PVD33365.1 - 0.046 13.5 0.0 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family EHN PF06441.12 PVD33365.1 - 0.14 12.6 0.2 0.38 11.1 0.2 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Na_sulph_symp PF00939.19 PVD33366.1 - 3e-82 277.2 4.6 6.7e-67 226.5 0.0 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PVD33366.1 - 1.1e-23 83.9 14.9 4.9e-15 55.5 6.6 3.0 2 1 1 3 3 3 2 Citrate transporter DUF5546 PF17700.1 PVD33366.1 - 0.21 11.9 3.1 0.13 12.6 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5546) zf-LITAF-like PF10601.9 PVD33367.1 - 1.2e-24 86.3 14.0 1.7e-24 85.9 14.0 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 PVD33367.1 - 0.0035 17.3 2.9 0.12 12.3 0.1 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 PVD33367.1 - 0.015 15.4 1.7 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.11 PVD33367.1 - 0.031 13.8 0.9 0.86 9.2 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_4 PF13717.6 PVD33367.1 - 0.045 13.7 3.2 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.6 PVD33367.1 - 0.061 14.0 3.8 6.2 7.6 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_7 PF02591.15 PVD33367.1 - 0.072 13.3 8.2 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain YacG PF03884.14 PVD33367.1 - 0.19 11.5 8.0 2.7 7.8 0.1 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG DZR PF12773.7 PVD33367.1 - 0.25 11.4 6.5 3.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon LRR_4 PF12799.7 PVD33368.1 - 2.8e-12 46.6 34.8 0.0021 18.4 3.3 7.2 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD33368.1 - 1.2e-10 40.9 36.0 0.00022 20.9 11.1 5.7 4 1 1 5 5 5 4 Leucine rich repeat IQ PF00612.27 PVD33368.1 - 5.9e-06 25.6 0.8 1.6e-05 24.2 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.6 PVD33368.1 - 0.36 11.0 22.5 25 5.3 0.0 8.3 8 1 1 9 9 9 0 Leucine Rich repeat CRAL_TRIO_2 PF13716.6 PVD33369.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Ank_2 PF12796.7 PVD33370.1 - 2.1e-39 134.0 0.9 3e-12 47.0 0.0 6.3 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33370.1 - 7.2e-33 112.2 2.5 1.7e-06 28.2 0.0 8.8 8 1 0 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33370.1 - 2.5e-32 110.8 2.1 3.3e-06 27.5 0.0 8.1 5 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33370.1 - 1.2e-28 96.0 8.4 0.00059 20.1 0.0 11.5 12 1 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 PVD33370.1 - 2.1e-23 81.7 10.0 0.0001 22.6 0.1 10.9 11 0 0 11 11 11 7 Ankyrin repeat GFO_IDH_MocA PF01408.22 PVD33371.1 - 1.5e-07 32.2 0.0 2.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PH PF00169.29 PVD33377.1 - 1e-14 54.9 0.0 2.4e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 PH domain WW PF00397.26 PVD33377.1 - 1.5e-05 24.9 0.2 4.7e-05 23.4 0.2 2.0 1 0 0 1 1 1 1 WW domain PH_11 PF15413.6 PVD33377.1 - 0.0021 18.4 0.6 0.0021 18.4 0.6 3.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 PVD33377.1 - 0.1 13.0 0.2 0.53 10.7 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain P-II PF00543.22 PVD33377.1 - 0.27 11.9 0.4 48 4.6 0.2 2.6 2 0 0 2 2 2 0 Nitrogen regulatory protein P-II DUF2564 PF10819.8 PVD33377.1 - 4.4 7.8 8.5 5.9 7.3 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DENN PF02141.21 PVD33378.1 - 3.5e-48 164.0 3.7 7.4e-48 163.0 3.7 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PVD33378.1 - 1.5e-13 51.2 0.3 4.4e-13 49.8 0.3 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 PVD33378.1 - 3.5e-08 33.3 3.3 1e-07 31.8 3.3 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 PVD33378.1 - 0.0066 16.4 0.5 0.014 15.3 0.5 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Ribosomal_L27A PF00828.19 PVD33379.1 - 8e-24 84.7 0.0 1.1e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sarcoglycan_1 PF04790.13 PVD33380.1 - 4.9e-39 134.2 0.9 6.7e-39 133.8 0.9 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Cas6 PF09559.10 PVD33380.1 - 0.00016 21.7 0.3 0.00078 19.5 0.0 2.2 3 0 0 3 3 3 1 Cas6 Crispr Vps39_2 PF10367.9 PVD33381.1 - 6.8e-29 100.5 1.6 1.1e-28 99.8 0.6 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 PVD33381.1 - 2.3e-17 63.2 0.1 1e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 PVD33381.1 - 8.5e-08 32.2 0.4 0.0012 18.7 0.1 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_14 PF13428.6 PVD33381.1 - 0.013 16.3 0.6 23 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33381.1 - 0.021 14.9 3.2 4.2 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3196 PF11428.8 PVD33381.1 - 0.025 14.1 0.2 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Herpes_UL49_5 PF05702.11 PVD33381.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein ANAPC3 PF12895.7 PVD33381.1 - 0.89 9.8 3.0 20 5.5 0.1 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PDZ PF00595.24 PVD33382.1 - 2.8e-31 107.7 4.0 8.3e-16 58.1 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD33382.1 - 5.4e-28 96.6 3.1 5.1e-14 51.9 1.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 PVD33382.1 - 4.6e-17 62.1 0.9 2.6e-08 34.1 0.2 2.6 2 0 0 2 2 2 2 PDZ domain Amidase_6 PF12671.7 PVD33382.1 - 0.00034 20.7 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 Putative amidase domain Tricorn_PDZ PF14685.6 PVD33382.1 - 0.0087 16.0 3.1 0.09 12.8 0.3 2.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF4930 PF16284.5 PVD33382.1 - 0.052 13.5 1.8 0.15 12.0 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4930) DUF3394 PF11874.8 PVD33382.1 - 0.17 11.5 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) EBP50_C PF09007.11 PVD33382.1 - 0.33 11.9 4.1 0.43 11.6 2.5 2.1 2 1 0 2 2 2 0 EBP50, C-terminal Ets PF00178.22 PVD33383.1 - 1.1e-31 109.1 1.7 1.5e-31 108.7 1.7 1.2 1 0 0 1 1 1 1 Ets-domain ANF_receptor PF01094.28 PVD33386.1 - 4.2e-38 131.3 0.0 5.7e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD33386.1 - 1.9e-21 76.5 0.0 3.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD33386.1 - 6e-15 55.3 0.0 9.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Syndecan PF01034.20 PVD33386.1 - 0.016 15.1 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4479 PF14794.6 PVD33386.1 - 0.066 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) TNFR_16_TM PF18422.1 PVD33386.1 - 0.2 11.7 0.8 0.42 10.6 0.8 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Guanylate_cyc PF00211.20 PVD33387.1 - 8.5e-60 201.5 0.0 1.4e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD33387.1 - 5.9e-07 29.1 1.3 8.6e-07 28.6 1.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase PF00069.25 PVD33387.1 - 2.1e-05 24.0 0.0 5.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33387.1 - 0.00027 20.3 0.0 0.57 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase SNAD1 PF18744.1 PVD33387.1 - 0.071 13.0 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 1 Dynein_AAA_lid PF17852.1 PVD33387.1 - 0.19 11.8 0.1 0.57 10.3 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain p450 PF00067.22 PVD33388.1 - 3.6e-96 322.7 0.0 5e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GHL10 PF02638.15 PVD33389.1 - 2.4e-70 237.1 0.6 5.5e-70 235.9 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 TPR_1 PF00515.28 PVD33389.1 - 3.6e-42 140.5 37.8 0.00018 21.2 0.0 13.5 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33389.1 - 1.8e-38 127.5 40.6 1.1e-05 25.1 0.1 15.7 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_19 PF14559.6 PVD33389.1 - 1.4e-35 121.6 5.6 7.1e-06 26.5 0.0 9.9 6 2 4 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 PVD33389.1 - 4.4e-35 117.3 16.7 0.0036 18.0 0.0 13.4 9 3 4 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33389.1 - 1.6e-29 99.6 26.5 0.0041 17.2 0.0 12.7 14 0 0 14 14 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 PVD33389.1 - 3.1e-29 101.3 25.9 5.1e-05 23.8 0.5 10.3 8 3 3 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 PVD33389.1 - 1.6e-24 86.0 36.1 1.1e-07 32.0 4.7 10.1 8 3 1 10 10 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 PVD33389.1 - 6.2e-20 70.1 23.9 0.19 12.2 0.1 15.0 14 2 1 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.6 PVD33389.1 - 7e-20 69.5 26.0 0.00026 20.8 0.2 11.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD33389.1 - 3.3e-19 68.3 24.9 0.00015 21.4 0.0 12.4 11 2 2 13 13 13 4 TPR repeat TPR_6 PF13174.6 PVD33389.1 - 2.3e-17 62.4 26.1 0.03 14.9 0.5 12.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD33389.1 - 2.4e-16 59.0 25.1 0.00011 22.0 0.2 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_9 PF13371.6 PVD33389.1 - 2.6e-09 37.1 10.2 0.037 14.2 0.0 7.7 6 2 2 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD33389.1 - 2.9e-07 30.6 25.8 0.13 12.5 0.1 6.9 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 PVD33389.1 - 0.00018 20.6 4.9 0.00018 20.6 4.9 5.4 4 2 1 6 6 4 1 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 PVD33389.1 - 0.008 15.0 0.1 0.6 8.8 0.0 3.0 1 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPPII_N PF12583.8 PVD33389.1 - 0.071 13.7 1.4 13 6.4 0.0 4.0 4 0 0 4 4 4 0 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 PVD33389.1 - 4.9 7.3 19.4 0.94 9.6 0.1 6.1 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Pentapeptide_4 PF13599.6 PVD33390.1 - 1.1e-243 788.0 202.3 1.3e-05 25.3 0.1 59.5 3 2 53 60 60 60 58 Pentapeptide repeats (9 copies) Keratin_B2 PF01500.17 PVD33390.1 - 0.002 18.1 693.4 0.012 15.6 13.8 49.5 1 1 25 27 27 27 10 Keratin, high sulfur B2 protein MciZ PF13072.6 PVD33393.1 - 0.21 11.4 0.4 0.4 10.5 0.4 1.4 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Ank_5 PF13857.6 PVD33394.1 - 1.1e-103 337.9 45.1 8.2e-09 35.6 0.0 24.2 21 4 3 24 24 24 20 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33394.1 - 1.2e-91 301.4 29.7 5.1e-10 39.8 0.1 17.9 11 6 7 19 19 19 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33394.1 - 1.2e-79 261.7 42.2 0.00029 21.3 0.0 29.2 14 7 18 32 32 32 22 Ankyrin repeats (many copies) Ank PF00023.30 PVD33394.1 - 1.7e-70 230.6 19.4 9.6e-06 25.8 0.1 29.4 32 2 0 32 32 32 15 Ankyrin repeat Ank_3 PF13606.6 PVD33394.1 - 7.2e-70 222.6 28.6 4.4e-06 26.6 0.1 30.5 34 0 0 34 34 34 14 Ankyrin repeat Shigella_OspC PF06128.11 PVD33394.1 - 0.01 15.6 6.8 6.3 6.4 0.1 5.9 6 0 0 6 6 6 0 Shigella flexneri OspC protein CH_2 PF06294.11 PVD33394.1 - 0.02 15.0 6.8 18 5.5 0.0 7.4 9 1 1 10 10 10 0 CH-like domain in sperm protein Ank_5 PF13857.6 PVD33395.1 - 7.7e-37 124.9 4.8 5.3e-09 36.2 0.0 8.7 7 1 2 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33395.1 - 2.5e-32 111.3 2.8 6.7e-07 29.8 0.0 8.4 4 3 3 9 9 9 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33395.1 - 1.1e-28 96.1 7.0 3.5e-05 23.9 0.0 13.1 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 PVD33395.1 - 1.7e-26 91.5 4.4 0.0013 19.0 0.0 11.1 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 PVD33395.1 - 1.9e-26 92.0 9.0 0.00042 20.8 0.1 11.2 6 4 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33396.1 - 7.5e-32 109.0 1.4 2.6e-08 34.0 0.0 5.2 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33396.1 - 6.7e-26 90.3 0.8 3.6e-06 27.4 0.0 6.3 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33396.1 - 1.7e-22 79.8 0.0 2.5e-08 34.4 0.1 4.2 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33396.1 - 7.1e-20 69.0 0.4 8.7e-07 28.8 0.1 7.2 8 1 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PVD33396.1 - 1.4e-18 66.4 0.0 1.2e-06 28.7 0.0 7.2 6 2 0 6 6 6 3 Ankyrin repeat DUF4792 PF16040.5 PVD33396.1 - 0.052 13.5 0.0 6.1 6.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4792) Glyco_hydro_71 PF03659.14 PVD33396.1 - 0.071 11.9 0.1 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 71 DUF5596 PF18082.1 PVD33396.1 - 0.083 12.7 0.0 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) DUF4767 PF15983.5 PVD33396.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) Ank_5 PF13857.6 PVD33397.1 - 4.8e-83 272.1 32.5 7.8e-07 29.3 0.1 20.7 19 5 1 20 20 20 15 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33397.1 - 1.8e-79 262.3 24.1 4.6e-10 39.9 0.1 16.0 8 4 9 17 17 17 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33397.1 - 2.4e-69 228.9 31.8 0.0014 19.2 0.1 24.9 14 6 13 27 27 27 18 Ankyrin repeats (many copies) Ank PF00023.30 PVD33397.1 - 3.2e-55 182.3 21.6 8.8e-06 25.9 0.1 25.7 29 0 0 29 29 28 9 Ankyrin repeat Ank_3 PF13606.6 PVD33397.1 - 8.5e-47 151.7 31.5 4e-06 26.8 0.1 24.1 26 0 0 26 26 25 8 Ankyrin repeat SOCS_box PF07525.16 PVD33397.1 - 1.1e-09 38.4 1.4 2.9e-09 37.1 1.4 1.8 1 0 0 1 1 1 1 SOCS box Shigella_OspC PF06128.11 PVD33397.1 - 0.0023 17.7 5.4 1.9 8.2 0.1 5.8 7 0 0 7 7 7 1 Shigella flexneri OspC protein CARD PF00619.21 PVD33397.1 - 0.034 14.2 0.0 0.87 9.7 0.0 3.1 2 0 0 2 2 2 0 Caspase recruitment domain DUF4767 PF15983.5 PVD33397.1 - 0.036 14.3 0.6 0.82 9.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4767) UvrD_C PF13361.6 PVD33397.1 - 0.047 13.1 0.3 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2666 PF10869.8 PVD33397.1 - 0.09 13.0 3.0 1.3e+02 2.8 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2666) Ank_5 PF13857.6 PVD33398.1 - 9.9e-29 99.0 10.2 9.7e-11 41.7 0.1 8.0 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD33398.1 - 4.9e-24 83.7 9.8 0.00035 20.9 0.0 9.9 10 0 0 10 10 10 7 Ankyrin repeat Ank_2 PF12796.7 PVD33398.1 - 3.4e-23 82.0 3.3 2.1e-08 34.6 0.0 5.6 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33398.1 - 4.1e-22 78.2 7.9 1.9e-05 25.1 0.3 8.3 5 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33398.1 - 1.4e-21 74.3 4.6 4.9e-05 23.4 0.0 9.2 10 1 0 10 10 10 5 Ankyrin repeat SOCS_box PF07525.16 PVD33398.1 - 1.8e-08 34.6 0.2 1.8e-08 34.6 0.2 2.0 2 0 0 2 2 2 1 SOCS box LysE PF01810.18 PVD33398.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 LysE type translocator Ank_4 PF13637.6 PVD33399.1 - 2.4e-26 91.8 8.4 0.00013 22.4 0.0 9.2 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33399.1 - 8.1e-24 83.4 6.9 2.3e-06 27.8 0.0 7.0 6 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD33399.1 - 3.9e-20 71.3 5.4 0.072 13.6 0.2 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_2 PF12796.7 PVD33399.1 - 8.4e-19 67.9 2.2 0.00018 22.1 0.0 5.4 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33399.1 - 2.6e-17 61.1 3.1 0.2 12.3 0.0 10.3 10 1 0 10 10 10 3 Ankyrin repeat SOCS_box PF07525.16 PVD33399.1 - 0.0067 16.8 2.0 0.017 15.5 2.0 1.7 1 0 0 1 1 1 1 SOCS box DUF4147 PF13660.6 PVD33399.1 - 0.067 12.7 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Ank_2 PF12796.7 PVD33400.1 - 9e-20 71.1 13.9 1.8e-10 41.3 1.5 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33400.1 - 8.8e-18 64.1 13.9 1.3e-05 25.4 0.1 6.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD33400.1 - 2.8e-14 52.8 8.1 0.0022 18.4 0.1 6.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 PVD33400.1 - 8.5e-14 51.7 0.8 0.0056 17.2 0.0 5.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33400.1 - 1.1e-10 40.7 0.4 0.0085 16.5 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat WavE PF07507.11 PVD33400.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Ank_5 PF13857.6 PVD33401.1 - 4e-66 218.2 23.4 5.9e-07 29.6 0.3 17.6 15 3 5 20 20 20 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33401.1 - 3.8e-61 203.6 23.6 2.4e-07 31.3 0.0 15.2 6 4 5 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33401.1 - 2.7e-55 184.0 22.4 0.0022 18.5 0.1 21.7 15 4 7 23 23 23 16 Ankyrin repeats (many copies) Ank PF00023.30 PVD33401.1 - 6.5e-52 171.8 23.3 0.00036 20.8 0.0 21.3 23 0 0 23 23 23 10 Ankyrin repeat Ank_3 PF13606.6 PVD33401.1 - 3.2e-45 146.9 21.4 0.0049 17.3 0.0 22.6 25 0 0 25 25 25 9 Ankyrin repeat SOCS_box PF07525.16 PVD33401.1 - 2.9e-06 27.5 0.5 7.2e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 SOCS box DUF249 PF03158.13 PVD33401.1 - 0.0059 16.3 0.7 0.22 11.2 0.0 3.9 3 1 1 4 4 4 1 Multigene family 530 protein CppA_N PF14506.6 PVD33401.1 - 0.053 13.6 0.1 3 7.9 0.0 3.3 3 1 0 3 3 3 0 CppA N-terminal Thyroglobulin_1 PF00086.18 PVD33402.1 - 2.8e-09 36.5 1.1 2.8e-09 36.5 1.1 2.8 3 0 0 3 3 3 1 Thyroglobulin type-1 repeat IGFBP PF00219.18 PVD33402.1 - 0.00081 20.0 10.1 0.00081 20.0 10.1 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein SH3_9 PF14604.6 PVD33403.1 - 5.2e-53 176.7 9.0 1.6e-13 50.3 0.1 6.8 7 0 0 7 7 7 6 Variant SH3 domain SH3_1 PF00018.28 PVD33403.1 - 1.1e-52 175.4 4.2 3.2e-11 42.7 0.0 6.8 6 0 0 6 6 6 6 SH3 domain SH3_2 PF07653.17 PVD33403.1 - 1.2e-43 146.5 0.8 1.5e-07 31.0 0.0 7.3 7 0 0 7 7 7 6 Variant SH3 domain RhoGEF PF00621.20 PVD33403.1 - 4.9e-40 137.7 2.2 1.2e-39 136.5 2.2 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 PVD33403.1 - 1.3e-15 57.7 0.8 1.3e-15 57.7 0.8 2.6 3 0 0 3 3 3 1 BAR domain hSH3 PF14603.6 PVD33403.1 - 0.0011 19.4 0.0 0.017 15.6 0.0 2.9 3 0 0 3 3 3 1 Helically-extended SH3 domain CENP-Q PF13094.6 PVD33403.1 - 0.0041 17.3 5.1 0.019 15.2 5.1 2.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-C2H2 PF00096.26 PVD33404.1 - 7.3e-37 123.8 88.9 0.00054 20.3 2.1 14.3 14 0 0 14 14 14 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33404.1 - 3.2e-28 96.0 89.2 0.0056 17.4 0.6 14.4 14 0 0 14 14 14 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD33404.1 - 1.7e-26 91.4 85.2 5.5e-06 26.6 0.7 14.1 14 0 0 14 14 14 9 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD33404.1 - 5.9e-08 32.5 82.2 0.032 14.2 1.8 13.8 14 0 0 14 14 14 7 C2H2-type zinc finger zf-met PF12874.7 PVD33404.1 - 7.7e-05 22.9 66.4 0.00076 19.8 0.6 11.8 14 0 0 14 14 14 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD33404.1 - 0.00043 20.5 67.7 0.0017 18.6 1.1 11.6 12 1 1 13 13 12 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD33404.1 - 0.0046 16.7 0.9 0.0046 16.7 0.9 8.9 10 0 0 10 10 10 4 zinc-finger C2H2-type ADK_lid PF05191.14 PVD33404.1 - 0.0074 16.2 1.0 0.0074 16.2 1.0 7.4 6 4 2 8 8 8 1 Adenylate kinase, active site lid zf_UBZ PF18439.1 PVD33404.1 - 0.0083 15.7 41.0 1.6 8.4 0.1 10.8 11 0 0 11 11 11 3 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 PVD33404.1 - 0.023 15.0 0.3 0.023 15.0 0.3 9.0 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) ZZ PF00569.17 PVD33404.1 - 8.5 6.3 22.1 52 3.8 0.1 7.1 6 0 0 6 6 6 0 Zinc finger, ZZ type UPF0160 PF03690.13 PVD33405.1 - 1.3e-138 462.0 0.0 1.4e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) WD40 PF00400.32 PVD33406.1 - 8.7e-05 23.2 8.6 0.24 12.3 1.5 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PTCB-BRCT PF12738.7 PVD33407.1 - 1.1e-47 159.8 4.4 4.9e-18 64.8 0.1 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 PVD33407.1 - 2.9e-34 117.3 6.2 1.8e-09 37.8 0.0 6.3 6 1 1 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PVD33407.1 - 1.8e-29 102.0 1.0 9.5e-06 25.9 0.0 6.4 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PVD33407.1 - 3.5e-19 68.5 0.1 1.6e-15 56.8 0.0 3.5 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 PVD33407.1 - 3.4e-07 30.5 4.7 0.00084 19.6 0.1 4.4 5 1 0 5 5 5 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 PVD33407.1 - 6.1e-07 29.5 0.6 0.0039 17.2 0.0 4.2 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain DUF2722 PF10846.8 PVD33407.1 - 0.0055 15.7 10.5 0.011 14.7 10.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PVD33407.1 - 0.0068 17.1 14.9 0.027 15.1 14.9 2.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 PVD33407.1 - 0.017 15.1 15.6 0.0098 15.9 13.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 PVD33407.1 - 0.15 12.0 6.5 0.37 10.7 6.5 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 PVD33407.1 - 0.39 9.3 1.4 0.62 8.7 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 PVD33407.1 - 1.5 9.2 7.1 4.1 7.8 7.1 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 PVD33407.1 - 5.4 6.6 23.7 12 5.5 23.7 1.5 1 0 0 1 1 1 0 Spt20 family SHS2_Rpb7-N PF03876.17 PVD33408.1 - 3e-10 40.3 0.0 5.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 PVD33408.1 - 1e-07 32.6 0.1 5.8e-07 30.2 0.0 1.9 1 1 1 2 2 2 1 RPA43 OB domain in RNA Pol I CLASP_N PF12348.8 PVD33409.1 - 1.3e-37 129.6 12.8 2.4e-09 37.1 0.0 7.5 7 2 1 8 8 8 5 CLASP N terminal HEAT PF02985.22 PVD33409.1 - 9.5e-15 53.5 11.7 0.011 16.0 0.0 10.4 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 PVD33409.1 - 2.4e-13 50.3 7.6 0.0042 17.4 0.1 9.9 8 2 4 12 12 11 5 HEAT repeats Cnd1 PF12717.7 PVD33409.1 - 1.4e-11 44.7 15.0 0.059 13.4 0.0 8.5 6 3 2 10 10 10 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PVD33409.1 - 1.2e-07 32.1 8.6 0.047 14.2 0.1 9.2 9 0 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PVD33409.1 - 3.2e-05 24.4 1.3 2.7 8.7 0.0 6.6 6 1 1 7 7 6 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 PVD33409.1 - 5.2e-05 23.4 1.0 1.2 9.3 0.0 5.7 4 1 0 4 4 4 1 Telomere-length maintenance and DNA damage repair Cohesin_HEAT PF12765.7 PVD33409.1 - 0.00017 21.8 0.6 2.8 8.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 PVD33409.1 - 0.00064 18.4 9.6 0.092 11.3 0.1 4.5 5 0 0 5 5 5 2 Adaptin N terminal region DUF4042 PF13251.6 PVD33409.1 - 0.034 13.9 0.7 3.7 7.2 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) DCB PF16213.5 PVD33409.1 - 3.3 7.3 10.2 14 5.3 0.1 4.6 5 0 0 5 5 5 0 Dimerisation and cyclophilin-binding domain of Mon2 RabGAP-TBC PF00566.18 PVD33410.1 - 9.2e-46 156.2 0.0 2.7e-45 154.7 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 PVD33410.1 - 1e-40 138.2 2.3 7e-22 77.5 0.2 2.4 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 PVD33410.1 - 0.00055 19.3 1.2 0.0021 17.5 0.1 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 PVD33410.1 - 0.0077 16.1 0.1 0.038 13.9 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 PVD33410.1 - 0.0085 15.9 0.5 0.03 14.2 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD33410.1 - 0.044 13.3 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 EF hand PHD PF00628.29 PVD33411.1 - 1.6e-11 43.9 8.4 1.6e-11 43.9 8.4 2.2 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 PVD33411.1 - 7.3e-10 39.0 21.7 2e-08 34.4 4.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 PVD33411.1 - 2.7e-07 30.3 5.0 2.7e-07 30.3 5.0 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD33411.1 - 1.2e-06 28.2 4.1 1.2e-06 28.2 4.1 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD33411.1 - 6.7e-06 25.9 2.1 6.7e-06 25.9 2.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD33411.1 - 0.00013 21.9 5.3 0.00013 21.9 5.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 PVD33411.1 - 0.0011 19.3 2.7 0.0011 19.3 2.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD33411.1 - 0.0026 17.7 2.1 0.0026 17.7 2.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Vps36-NZF-N PF16988.5 PVD33411.1 - 0.23 10.9 2.1 0.65 9.4 0.0 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-ANAPC11 PF12861.7 PVD33411.1 - 1.3 9.1 9.3 0.39 10.8 0.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PVD33411.1 - 1.5 8.7 20.9 0.019 14.8 2.4 3.9 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD33411.1 - 4.7 7.5 15.5 0.036 14.2 5.0 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_M20 PF01546.28 PVD33413.1 - 3.9e-35 121.5 0.0 5.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PVD33413.1 - 6.5e-13 48.6 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CDP-OH_P_transf PF01066.21 PVD33414.1 - 2.1e-18 66.8 0.1 2.1e-18 66.8 0.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TNFR_16_TM PF18422.1 PVD33414.1 - 0.042 13.8 0.7 1.1 9.3 0.2 3.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF1772 PF08592.11 PVD33414.1 - 0.32 11.3 3.6 4.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) TM_helix PF05552.12 PVD33414.1 - 2.2 8.3 5.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Conserved TM helix LRR_4 PF12799.7 PVD33415.1 - 8.7e-12 45.1 14.5 0.0018 18.6 0.8 4.0 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD33415.1 - 3.9e-10 39.3 20.7 7.8e-05 22.4 2.2 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 PVD33415.1 - 3.1e-08 33.3 4.5 6.6e-05 22.5 1.9 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PVD33415.1 - 0.086 12.9 12.4 0.24 11.6 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 PVD33415.1 - 2.1 9.2 12.4 41 5.3 0.4 5.3 4 1 1 5 5 5 0 Leucine Rich Repeat tRNA-synt_1e PF01406.19 PVD33416.1 - 3.3e-122 407.6 0.2 5.6e-122 406.8 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PVD33416.1 - 3.5e-07 29.3 0.3 0.0003 19.7 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PVD33416.1 - 0.00037 18.9 0.2 0.0046 15.3 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) FliG_C PF01706.16 PVD33416.1 - 0.47 10.7 6.1 18 5.6 0.3 3.6 4 0 0 4 4 4 0 FliG C-terminal domain CAP_N PF01213.19 PVD33418.1 - 0.027 14.0 0.9 0.032 13.7 0.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CYSTM PF12734.7 PVD33418.1 - 0.54 10.6 3.2 0.95 9.8 0.4 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF2102 PF09875.9 PVD33419.1 - 0.09 12.5 0.1 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) PCI PF01399.27 PVD33423.1 - 4.9e-12 46.3 1.6 4.9e-12 46.3 1.6 2.2 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 PVD33423.1 - 2.5e-07 30.3 0.1 6.3e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Ldl_recept_b PF00058.17 PVD33424.1 - 1.1e-121 397.0 40.6 1.2e-14 54.4 0.3 17.6 17 0 0 17 17 17 16 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD33424.1 - 3.6e-36 123.1 76.7 2.4e-12 46.9 8.0 5.9 5 0 0 5 5 4 4 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 PVD33424.1 - 2.1e-23 83.0 0.0 0.0017 17.7 0.0 6.2 4 3 2 6 6 6 5 Domain of unknown function (DUF5050) Ldl_recept_a PF00057.18 PVD33424.1 - 4.9e-21 74.6 32.2 9.2e-11 41.8 11.3 3.7 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SGL PF08450.12 PVD33424.1 - 9.5e-17 61.4 13.1 0.044 13.4 0.1 10.3 5 3 5 10 10 10 6 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 PVD33424.1 - 1.9e-05 24.4 3.9 2.3 8.4 0.0 7.7 9 0 0 9 9 9 1 NHL repeat Arylesterase PF01731.20 PVD33424.1 - 0.00039 20.6 0.7 35 4.7 0.0 6.4 7 1 1 8 8 7 0 Arylesterase ASFV_J13L PF05568.11 PVD33424.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein cEGF PF12662.7 PVD33424.1 - 0.0062 16.5 21.3 0.19 11.7 0.2 5.0 4 0 0 4 4 4 2 Complement Clr-like EGF-like SKG6 PF08693.10 PVD33424.1 - 0.02 14.3 4.8 0.055 12.9 4.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 PVD33424.1 - 0.064 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 PVD33424.1 - 0.08 13.8 0.2 0.22 12.4 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2572 PF10833.8 PVD33424.1 - 0.082 12.7 0.0 1.4 8.6 0.0 3.2 4 1 1 5 5 4 0 Protein of unknown function (DUF2572) YoeB_toxin PF06769.14 PVD33424.1 - 0.15 12.2 5.9 3.1 7.9 0.2 4.3 4 0 0 4 4 4 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Adeno_E3_CR2 PF02439.15 PVD33424.1 - 3.2 7.6 9.1 6.4 6.6 9.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SL4P PF17618.2 PVD33424.1 - 5.9 7.0 19.2 13 5.9 0.0 7.5 10 0 0 10 10 8 0 Uncharacterized Strongylid L4 protein Iso_dh PF00180.20 PVD33425.1 - 2.9e-64 217.4 0.0 4.3e-39 134.6 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase PARP PF00644.20 PVD33426.1 - 3.8e-27 95.1 0.1 8.5e-20 71.2 0.0 2.8 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF3907 PF13047.6 PVD33426.1 - 0.32 10.9 1.7 0.59 10.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) BSP_II PF05432.11 PVD33426.1 - 1.3 8.6 12.8 3.9 7.1 12.8 1.8 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Uso1_p115_C PF04871.13 PVD33426.1 - 7.2 7.0 13.4 1 9.7 5.8 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EURL PF06937.11 PVD33428.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 EURL protein adh_short_C2 PF13561.6 PVD33429.1 - 3.5e-52 177.3 0.0 4.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD33429.1 - 2.3e-49 167.5 0.0 2.8e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD33429.1 - 2.4e-07 30.8 0.0 5.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD33429.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 PVD33429.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.32 PVD33430.1 - 6.7e-15 55.2 2.0 0.0032 18.3 0.0 8.7 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD33430.1 - 4.9e-05 23.5 0.0 1.8 8.9 0.0 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PC4 PF02229.16 PVD33432.1 - 3.2e-09 36.3 0.0 4.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CAP_N PF01213.19 PVD33435.1 - 0.36 10.3 14.3 0.66 9.4 6.9 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pantoate_transf PF02548.15 PVD33436.1 - 0.027 13.8 0.0 0.03 13.7 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase MMS1_N PF10433.9 PVD33437.1 - 1.7e-109 366.7 0.0 5.4e-109 365.0 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PVD33437.1 - 1.8e-49 168.8 0.0 2.9e-36 125.4 0.0 3.8 4 0 0 4 4 4 2 CPSF A subunit region Ku PF02735.16 PVD33438.1 - 1.3e-52 178.5 0.1 2.2e-52 177.8 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 PVD33438.1 - 1.1e-45 156.1 0.0 1.9e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PVD33438.1 - 6e-19 68.5 0.5 6e-19 68.5 0.5 2.5 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 PVD33438.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Cylicin_N PF15241.6 PVD33438.1 - 0.037 14.1 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Cylicin N-terminus B12D PF06522.11 PVD33438.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit VWA_2 PF13519.6 PVD33438.1 - 0.13 12.9 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain TIP49_C PF17856.1 PVD33439.1 - 2.9e-29 101.0 0.6 5.4e-29 100.1 0.6 1.5 1 0 0 1 1 1 1 TIP49 AAA-lid domain TIP49 PF06068.13 PVD33439.1 - 1.1e-16 61.0 0.8 3.3e-09 36.4 0.0 2.4 2 1 1 3 3 3 2 TIP49 P-loop domain TFIID-31kDa PF02291.15 PVD33439.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SNF PF00209.18 PVD33440.1 - 2.3e-199 663.4 34.9 4.7e-199 662.4 34.9 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SAM_1 PF00536.30 PVD33441.1 - 2.4e-32 111.2 3.1 3.3e-13 49.8 0.2 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD33441.1 - 3.4e-32 110.4 5.9 1.9e-12 47.1 0.0 3.9 3 1 0 3 3 3 3 SAM domain (Sterile alpha motif) PKcGMP_CC PF16808.5 PVD33441.1 - 0.0063 16.3 2.2 0.03 14.2 2.2 2.2 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase GrpE PF01025.19 PVD33441.1 - 0.014 15.0 6.6 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 GrpE DUF3837 PF12939.7 PVD33441.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) FdhE PF04216.12 PVD33441.1 - 0.3 10.9 2.2 0.47 10.3 2.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Lebercilin PF15619.6 PVD33441.1 - 1.1 8.9 16.7 0.32 10.6 13.7 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 PVD33441.1 - 2.1 7.4 8.5 5.1 6.1 8.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 PVD33441.1 - 5.3 6.3 6.9 2.5 7.4 4.4 1.7 1 1 0 1 1 1 0 FAM76 protein Oxysterol_BP PF01237.18 PVD33443.1 - 3.9e-92 309.0 0.3 7.7e-90 301.4 0.3 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 PVD33443.1 - 3.2e-10 40.5 0.0 9.8e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD33443.1 - 0.065 13.7 0.2 0.065 13.7 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SR-25 PF10500.9 PVD33443.1 - 1.9 8.0 13.8 1 8.9 5.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RANK_CRD_2 PF18278.1 PVD33444.1 - 0.055 13.6 19.6 0.9 9.7 1.0 5.4 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 C1q PF00386.21 PVD33445.1 - 1.1e-11 45.0 0.1 1.3e-10 41.5 0.1 2.0 1 1 0 1 1 1 1 C1q domain GvpG PF05120.12 PVD33446.1 - 1.9 8.6 5.7 1.5 8.9 0.5 3.3 4 0 0 4 4 4 0 Gas vesicle protein G YacG PF03884.14 PVD33448.1 - 0.071 12.9 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG ZT_dimer PF16916.5 PVD33449.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Dimerisation domain of Zinc Transporter NAD_binding_1 PF00175.21 PVD33450.1 - 2.3e-36 124.7 0.0 3.7e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PVD33450.1 - 4.3e-36 123.2 0.0 6.6e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PVD33450.1 - 0.0022 18.1 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DENN PF02141.21 PVD33451.1 - 1.8e-35 122.6 1.8 4.3e-35 121.3 1.8 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PVD33451.1 - 2.1e-18 66.8 1.6 6.1e-18 65.3 0.1 2.6 2 0 0 2 2 2 1 uDENN domain GNAT_acetyltr_2 PF13718.6 PVD33452.1 - 2.1e-102 341.4 0.0 3.7e-102 340.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 PVD33452.1 - 4.2e-77 259.0 7.1 7.4e-77 258.2 7.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 PVD33452.1 - 8.3e-62 208.2 0.0 2.3e-61 206.7 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 PVD33452.1 - 3.6e-33 113.3 0.1 9.2e-33 112.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 PVD33452.1 - 6.1e-05 23.4 0.0 0.0012 19.2 0.0 2.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD33452.1 - 0.00026 21.2 0.0 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DEAD PF00270.29 PVD33452.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1846 PF08903.11 PVD33452.1 - 0.071 11.6 0.0 0.16 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) PKcGMP_CC PF16808.5 PVD33452.1 - 0.11 12.4 0.5 0.3 11.0 0.5 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Acetyltransf_10 PF13673.7 PVD33452.1 - 0.13 12.2 0.0 0.75 9.7 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain 7tm_1 PF00001.21 PVD33453.1 - 5.2e-06 26.0 0.0 0.00083 18.8 0.0 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.6 PVD33453.1 - 0.075 13.3 0.5 24 5.3 0.0 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Saf_2TM PF18303.1 PVD33453.1 - 0.091 12.3 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF485 PF04341.12 PVD33454.1 - 0.0066 16.4 3.5 0.0083 16.1 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF485 DUF2232 PF09991.9 PVD33454.1 - 0.017 14.3 0.6 0.017 14.3 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Telomere_reg-2 PF10193.9 PVD33454.1 - 0.036 14.5 0.2 0.058 13.8 0.1 1.4 1 1 1 2 2 2 0 Telomere length regulation protein 7tm_1 PF00001.21 PVD33455.1 - 6.6e-22 78.1 18.2 9.9e-09 34.9 6.4 3.1 2 1 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) DUF2172 PF09940.9 PVD33455.1 - 0.0017 18.7 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2172) 7tm_1 PF00001.21 PVD33456.1 - 8.6e-12 44.9 0.5 1.4e-11 44.2 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD33456.1 - 0.064 12.5 0.5 4.7 6.4 0.1 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD33457.1 - 7.2e-09 35.3 1.0 9.5e-09 35.0 1.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CytochromB561_N PF09786.9 PVD33457.1 - 0.013 14.6 2.1 0.016 14.3 2.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal 7TM_GPCR_Sru PF10322.9 PVD33457.1 - 0.023 14.1 0.7 0.029 13.7 0.7 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Ammonium_transp PF00909.21 PVD33457.1 - 0.12 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family 7tm_1 PF00001.21 PVD33458.1 - 1.7e-16 60.3 20.6 1.4e-10 41.0 11.6 2.9 2 1 1 3 3 3 3 7 transmembrane receptor (rhodopsin family) DUF2681 PF10883.8 PVD33458.1 - 0.00078 19.8 7.7 0.13 12.7 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF2681) YihI PF04220.12 PVD33458.1 - 0.0043 16.8 2.5 0.0043 16.8 2.5 2.0 3 0 0 3 3 3 1 Der GTPase activator (YihI) DUF2371 PF10177.9 PVD33458.1 - 0.039 14.1 0.0 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF5385 PF17359.2 PVD33458.1 - 0.41 10.2 7.3 0.84 9.2 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5385) Tropomodulin PF03250.14 PVD33458.1 - 0.52 10.4 3.6 16 5.6 0.4 2.5 2 0 0 2 2 2 0 Tropomodulin Sigma_reg_N PF13800.6 PVD33458.1 - 4.5 7.6 16.4 13 6.2 1.3 4.8 5 1 1 6 6 6 0 Sigma factor regulator N-terminal Zip PF02535.22 PVD33459.1 - 5e-104 348.1 22.9 1.5e-51 175.6 1.3 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter OspE PF02471.17 PVD33459.1 - 0.0066 16.6 0.1 0.92 9.7 0.0 2.6 2 0 0 2 2 2 1 Borrelia outer surface protein E DUF577 PF04510.12 PVD33459.1 - 0.028 14.3 0.0 9.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF577) LRR19-TM PF15176.6 PVD33459.1 - 0.069 13.2 0.1 17 5.5 0.0 3.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain tRNA-synt_2_TM PF16995.5 PVD33459.1 - 0.077 12.7 0.1 0.077 12.7 0.1 3.9 5 1 1 6 6 6 0 Transmembrane region of lysyl-tRNA synthetase PsbM PF05151.12 PVD33459.1 - 1.4 8.8 8.0 10 6.0 0.0 3.5 3 0 0 3 3 3 0 Photosystem II reaction centre M protein (PsbM) GtrA PF04138.14 PVD33459.1 - 7.1 6.9 13.3 3.4 7.9 0.8 3.2 3 0 0 3 3 3 0 GtrA-like protein Actin PF00022.19 PVD33460.1 - 6.3e-143 476.3 0.0 7.1e-143 476.1 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3492 PF11997.8 PVD33460.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) TSSC4 PF15264.6 PVD33461.1 - 1.2e-20 74.0 8.1 1.2e-20 74.0 8.1 1.9 2 1 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 Casc1_N PF15927.5 PVD33462.1 - 3e-39 134.8 0.1 3e-39 134.8 0.1 3.4 3 1 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus Casc1 PF12366.8 PVD33462.1 - 0.00038 20.1 7.8 0.41 10.1 2.8 4.3 3 1 0 3 3 3 2 Cancer susceptibility candidate 1 Epimerase PF01370.21 PVD33464.1 - 9.1e-17 61.3 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PVD33464.1 - 1.5e-13 50.4 0.0 3.8e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 PVD33464.1 - 9e-10 38.5 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PVD33464.1 - 1.2e-09 38.4 0.0 2.2e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PVD33464.1 - 2e-08 33.7 0.0 8.2e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PVD33464.1 - 0.0022 17.4 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PVD33464.1 - 0.0083 15.3 0.1 2.7 7.1 0.0 3.0 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 PVD33464.1 - 0.048 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF2045 PF09741.9 PVD33465.1 - 2.1e-85 285.8 0.9 2.8e-85 285.4 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) DNA_binding_1 PF01035.20 PVD33465.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Mitochondr_Som1 PF11093.8 PVD33466.1 - 0.16 12.0 1.5 0.38 10.8 1.5 1.6 1 0 0 1 1 1 0 Mitochondrial export protein Som1 MAM PF00629.23 PVD33467.1 - 1e-30 106.8 1.2 1.7e-30 106.1 0.1 2.0 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Sushi PF00084.20 PVD33467.1 - 3.1e-06 27.7 1.5 0.0025 18.4 0.5 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) MAM PF00629.23 PVD33468.1 - 9.4e-44 149.1 0.1 9.4e-44 149.1 0.1 2.3 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Sushi PF00084.20 PVD33468.1 - 2.6e-06 27.9 0.3 8.8e-06 26.2 0.3 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF2613 PF11021.8 PVD33468.1 - 4.5 7.5 7.7 5.1 7.3 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2613) MAM PF00629.23 PVD33469.1 - 0.002 18.1 1.1 0.0038 17.2 0.1 1.8 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu MAM PF00629.23 PVD33470.1 - 1.4e-42 145.4 0.0 2.9e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 PVD33470.1 - 3.9e-09 37.0 2.6 0.00021 21.8 0.1 2.6 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) DUF1376 PF07120.11 PVD33470.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) GLTT PF01744.20 PVD33470.1 - 0.65 9.8 2.9 2.7 7.8 0.4 2.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) Guanylate_cyc PF00211.20 PVD33471.1 - 1.4e-62 210.5 0.2 2.8e-62 209.6 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 PVD33471.1 - 1.3e-45 156.1 0.0 1.8e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD33471.1 - 8.4e-35 120.3 0.0 2.3e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD33471.1 - 4.5e-26 91.8 0.0 8.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 PVD33471.1 - 0.00013 21.5 0.5 0.00021 20.8 0.5 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 PVD33471.1 - 0.00029 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Kinase-like PF14531.6 PVD33471.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RFX_DNA_binding PF02257.15 PVD33472.1 - 3.9e-31 107.5 0.2 7.5e-31 106.6 0.2 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 PVD33472.1 - 0.093 13.2 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 Poxvirus D5 protein-like Ras PF00071.22 PVD33475.1 - 2.5e-16 59.7 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD33475.1 - 5.3e-09 36.3 0.0 6.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD33475.1 - 0.00048 19.6 0.0 0.00065 19.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 PVD33475.1 - 0.00068 20.1 0.1 0.0017 18.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 PVD33475.1 - 0.00069 19.7 0.0 0.00089 19.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PVD33475.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PVD33475.1 - 0.034 14.2 0.4 0.72 9.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 PVD33475.1 - 0.034 14.0 0.1 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 PVD33475.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SIS PF01380.22 PVD33475.1 - 0.067 13.0 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 SIS domain DUF815 PF05673.13 PVD33475.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 PVD33475.1 - 0.18 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Septin Lectin_C PF00059.21 PVD33476.1 - 0.0047 17.6 2.1 0.0055 17.4 0.1 2.2 2 1 0 2 2 2 1 Lectin C-type domain Lectin_C PF00059.21 PVD33477.1 - 3.5e-12 47.0 1.2 1.9e-06 28.6 0.1 2.8 2 0 0 2 2 2 2 Lectin C-type domain Peptidase_S8 PF00082.22 PVD33477.1 - 0.54 9.5 4.9 0.94 8.7 2.2 2.1 2 0 0 2 2 2 0 Subtilase family Lysis_col PF02402.16 PVD33477.1 - 3.2 7.5 6.2 18 5.1 0.3 2.5 2 0 0 2 2 2 0 Lysis protein Lectin_C PF00059.21 PVD33478.1 - 2.2e-10 41.2 3.7 2.2e-10 41.2 3.7 3.1 4 0 0 4 4 4 1 Lectin C-type domain Inhibitor_I68 PF10468.9 PVD33478.1 - 0.0006 20.2 9.1 0.011 16.2 0.2 3.5 3 0 0 3 3 3 2 Carboxypeptidase inhibitor I68 DUF3437 PF11919.8 PVD33478.1 - 0.11 12.5 0.0 27 4.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) zf-Tim10_DDP PF02953.15 PVD33478.1 - 0.16 11.6 5.2 4.6 7.0 0.1 3.5 3 0 0 3 3 3 0 Tim10/DDP family zinc finger SOCS_box PF07525.16 PVD33479.1 - 6.1e-07 29.7 0.6 1.5e-06 28.4 0.6 1.7 1 0 0 1 1 1 1 SOCS box DUF4551 PF15087.6 PVD33479.1 - 2.6 6.8 17.3 4.1 6.1 17.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) 7tm_1 PF00001.21 PVD33480.1 - 8.2e-20 71.2 0.0 1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF485 PF04341.12 PVD33480.1 - 0.021 14.7 0.4 0.56 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 FKBP_C PF00254.28 PVD33481.1 - 1.4e-51 172.8 0.2 2.7e-33 114.1 0.0 2.5 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PVD33481.1 - 1.5e-24 84.7 4.8 1.4e-08 34.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33481.1 - 5e-20 69.9 4.1 2.4e-06 27.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33481.1 - 2.1e-15 55.6 5.0 1.8e-05 24.6 0.7 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD33481.1 - 5.9e-11 42.3 0.6 0.0039 17.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD33481.1 - 1.6e-10 40.3 4.1 0.007 16.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD33481.1 - 6.4e-10 39.5 0.2 2e-06 28.3 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD33481.1 - 1.2e-09 38.3 2.8 1.8e-05 24.9 2.2 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD33481.1 - 4.4e-09 35.9 3.0 0.0036 17.0 0.1 3.5 2 1 1 3 3 3 3 TPR repeat Fis1_TPR_C PF14853.6 PVD33481.1 - 2.5e-08 33.9 8.0 0.0011 19.0 0.2 3.5 3 0 0 3 3 3 3 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 PVD33481.1 - 3.7e-07 30.5 2.1 8.7e-05 23.0 0.3 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD33481.1 - 5.9e-06 26.3 2.6 0.0018 18.5 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD33481.1 - 7.9e-06 25.9 0.0 2.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD33481.1 - 8.7e-06 26.1 0.2 0.53 11.3 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD33481.1 - 3e-05 23.7 1.4 0.67 9.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PknG_TPR PF16918.5 PVD33481.1 - 0.0054 15.5 0.1 0.0078 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 PVD33481.1 - 0.011 16.0 6.7 0.092 13.0 2.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 PVD33481.1 - 0.02 15.3 1.0 0.051 14.0 0.7 1.8 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation PPR PF01535.20 PVD33481.1 - 0.13 12.6 0.4 1.5 9.3 0.0 2.8 2 0 0 2 2 2 0 PPR repeat Tfb4 PF03850.14 PVD33481.1 - 0.61 9.5 2.4 0.91 9.0 2.4 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 MIT PF04212.18 PVD33481.1 - 3.3 7.8 13.1 0.8 9.8 0.7 3.3 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain UDPG_MGDP_dh PF00984.19 PVD33482.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Pox_A8 PF04745.12 PVD33483.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 VITF-3 subunit protein CPW_WPC PF09717.10 PVD33483.1 - 0.11 13.4 5.3 0.82 10.7 0.3 2.8 2 1 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Ank_5 PF13857.6 PVD33484.1 - 1e-14 54.4 0.4 0.0013 18.9 0.3 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33484.1 - 2.4e-11 43.9 3.9 0.11 13.1 0.1 7.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33484.1 - 4.8e-10 39.9 1.0 0.002 18.7 0.4 5.1 1 1 6 7 7 7 4 Ankyrin repeats (3 copies) SOCS_box PF07525.16 PVD33484.1 - 1.2e-09 38.4 1.4 2.4e-09 37.4 1.4 1.6 1 0 0 1 1 1 1 SOCS box Ank PF00023.30 PVD33484.1 - 2.1e-07 31.1 0.0 0.077 13.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD33484.1 - 2.6e-07 30.4 0.3 0.67 10.7 0.0 7.1 8 1 0 8 8 8 1 Ankyrin repeat PDZ_3 PF17815.1 PVD33484.1 - 0.03 14.2 2.0 0.39 10.6 1.5 2.9 3 1 1 4 4 4 0 PDZ domain PROCT PF08084.11 PVD33484.1 - 0.091 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PROCT (NUC072) domain Ank_5 PF13857.6 PVD33485.1 - 5.5e-50 166.8 20.1 1.6e-09 37.9 0.0 13.5 11 4 3 14 14 14 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33485.1 - 4.9e-48 161.6 17.9 3.8e-06 27.4 0.1 11.4 4 2 6 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33485.1 - 3e-39 132.9 28.2 1.3e-06 28.8 0.2 17.3 9 4 10 19 19 19 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33485.1 - 3e-34 113.1 14.1 0.00016 21.9 0.0 19.4 22 0 0 22 22 22 6 Ankyrin repeat Ank PF00023.30 PVD33485.1 - 1.3e-24 85.5 21.4 0.0064 16.9 0.0 15.9 18 2 0 18 18 18 6 Ankyrin repeat GFRP PF06399.13 PVD33485.1 - 0.11 12.4 0.0 4.1 7.4 0.0 3.2 2 1 1 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Ank_4 PF13637.6 PVD33486.1 - 2.6e-26 91.6 11.8 1e-09 38.7 0.3 6.9 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33486.1 - 4.4e-26 91.3 17.4 1.4e-08 35.2 0.7 5.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33486.1 - 5.5e-23 80.7 8.5 9.2e-07 29.0 0.2 5.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD33486.1 - 1.2e-20 72.9 13.1 0.009 16.4 0.2 9.4 11 0 0 11 11 11 5 Ankyrin repeat Ank_3 PF13606.6 PVD33486.1 - 1.8e-19 67.8 9.4 0.00037 20.7 0.1 8.9 10 1 0 10 10 10 4 Ankyrin repeat Ank_2 PF12796.7 PVD33487.1 - 1.8e-29 102.1 6.2 4.5e-08 33.6 0.0 6.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33487.1 - 8.4e-26 90.0 6.0 4.7e-06 27.1 0.0 10.0 5 4 6 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD33487.1 - 3.8e-24 84.0 7.3 3.4e-06 27.3 0.1 10.3 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 PVD33487.1 - 3.4e-23 81.4 8.6 1.5e-08 34.7 0.1 6.8 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33487.1 - 4.1e-21 72.8 4.7 2.4e-05 24.3 0.0 11.8 14 0 0 14 14 14 3 Ankyrin repeat PilN PF05137.13 PVD33487.1 - 0.088 12.9 0.2 0.4 10.8 0.2 2.2 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) SOCS_box PF07525.16 PVD33488.1 - 2e-08 34.4 1.0 3.5e-08 33.7 1.0 1.4 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD33488.1 - 4e-07 30.5 0.1 0.21 12.2 0.0 5.3 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33488.1 - 6.8e-07 29.5 0.0 2.8 8.4 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD33488.1 - 5.4e-06 26.6 0.0 0.04 14.4 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 PVD33488.1 - 3.2e-05 24.4 0.0 0.079 13.6 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) AIG1 PF04548.16 PVD33488.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Ank_5 PF13857.6 PVD33489.1 - 6.5e-11 42.3 3.6 9.2e-05 22.6 1.4 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD33489.1 - 8.9e-10 38.8 1.4 1.9e-09 37.7 1.4 1.6 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 PVD33489.1 - 4.8e-08 33.5 2.8 0.00025 21.5 1.2 3.9 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33489.1 - 7.7e-08 32.7 2.8 0.035 14.7 0.2 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD33489.1 - 8.9e-08 32.2 2.7 0.008 16.6 0.1 4.5 4 1 1 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 PVD33489.1 - 1.2e-05 25.3 1.8 0.092 13.4 0.1 5.5 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 PVD33490.1 - 5.6e-63 208.6 23.1 3.1e-09 37.2 0.2 16.2 10 5 6 17 17 17 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33490.1 - 2.9e-60 199.5 24.0 5.8e-08 32.8 0.3 13.7 11 2 2 14 14 14 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33490.1 - 2.1e-58 194.9 37.1 4e-08 33.7 1.7 12.2 3 3 8 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33490.1 - 4.4e-51 169.2 23.4 7e-05 23.1 0.0 18.1 17 1 0 17 17 17 11 Ankyrin repeat Ank_3 PF13606.6 PVD33490.1 - 1e-50 163.7 14.5 7.4e-05 22.9 0.0 18.7 21 0 0 21 21 21 11 Ankyrin repeat SOCS_box PF07525.16 PVD33491.1 - 1.7e-10 41.1 1.3 3.2e-10 40.2 1.3 1.4 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD33492.1 - 6.4e-61 202.0 28.2 4.2e-09 36.8 0.2 17.2 9 4 10 19 19 19 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33492.1 - 1.3e-59 197.4 18.6 5.9e-06 26.5 0.1 13.6 14 1 1 15 15 15 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33492.1 - 6.5e-56 186.9 34.8 5.6e-10 39.7 0.2 14.0 3 2 10 15 15 15 13 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33492.1 - 5.3e-54 178.4 27.0 9e-07 29.1 0.1 18.0 19 0 0 19 19 19 11 Ankyrin repeat Ank_3 PF13606.6 PVD33492.1 - 1.6e-49 160.1 10.6 0.0008 19.7 0.0 19.1 22 0 0 22 22 22 10 Ankyrin repeat SOCS_box PF07525.16 PVD33492.1 - 3.4e-06 27.3 0.9 9e-06 25.9 0.9 1.8 1 0 0 1 1 1 1 SOCS box Shigella_OspC PF06128.11 PVD33492.1 - 8.6 6.0 13.2 7 6.3 0.1 4.5 6 0 0 6 6 6 0 Shigella flexneri OspC protein Ank_2 PF12796.7 PVD33493.1 - 9.6e-53 176.7 20.6 6e-09 36.4 0.3 9.3 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33493.1 - 9e-50 166.1 24.8 1.1e-07 32.0 0.1 11.9 9 3 4 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 PVD33493.1 - 8.2e-44 146.2 19.9 7.3e-05 23.0 0.0 14.7 16 0 0 16 16 16 9 Ankyrin repeat Ank_4 PF13637.6 PVD33493.1 - 1.5e-43 146.6 19.3 9.1e-07 29.3 0.1 12.2 7 4 4 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33493.1 - 1.5e-42 138.7 13.3 0.00059 20.1 0.0 14.5 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 PVD33494.1 - 5.1e-37 125.4 0.4 1.6e-06 28.2 0.0 8.7 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33494.1 - 3.6e-24 85.2 6.7 0.018 15.6 0.0 8.8 6 3 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33494.1 - 1e-21 74.7 2.4 0.00027 21.1 0.0 12.6 14 0 0 14 14 14 3 Ankyrin repeat Ank_4 PF13637.6 PVD33494.1 - 4.9e-21 74.8 7.8 0.47 11.1 0.0 11.5 10 2 3 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD33494.1 - 7.4e-20 70.4 0.0 5.4e-07 29.8 0.1 11.2 13 1 0 13 13 13 3 Ankyrin repeat PH_9 PF15410.6 PVD33494.1 - 0.14 12.5 0.2 20 5.6 0.0 3.5 4 0 0 4 4 4 0 Pleckstrin homology domain Ank_4 PF13637.6 PVD33495.1 - 4.9e-89 291.6 37.1 3.7e-07 30.6 0.0 20.4 12 7 8 21 21 21 17 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33495.1 - 1.1e-82 272.7 26.0 1.6e-09 38.2 0.0 13.1 5 4 8 14 14 14 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33495.1 - 4e-79 259.6 36.9 5.4e-07 29.8 0.0 20.1 15 7 9 24 24 24 17 Ankyrin repeats (many copies) Ank PF00023.30 PVD33495.1 - 2.1e-68 223.9 28.2 0.00019 21.7 0.0 24.8 22 5 2 24 24 24 15 Ankyrin repeat Ank_3 PF13606.6 PVD33495.1 - 1.9e-64 206.0 24.7 0.00027 21.2 0.0 26.8 28 2 1 29 29 29 11 Ankyrin repeat DUF249 PF03158.13 PVD33495.1 - 0.0025 17.6 0.7 20 4.8 0.0 5.4 5 1 2 7 7 7 1 Multigene family 530 protein DUF327 PF03885.13 PVD33495.1 - 0.041 13.8 0.5 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Ank_5 PF13857.6 PVD33496.1 - 1.4e-42 143.2 6.9 3e-08 33.8 0.0 9.0 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33496.1 - 8.6e-39 132.0 2.8 2.9e-11 43.8 0.1 6.3 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33496.1 - 1.5e-38 130.7 9.4 4.1e-06 27.2 0.0 11.1 7 3 6 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD33496.1 - 3.3e-33 112.7 5.2 1.4e-07 31.7 0.0 10.6 11 1 0 11 11 11 5 Ankyrin repeat Ank_3 PF13606.6 PVD33496.1 - 1.2e-32 108.2 5.1 2.5e-06 27.4 0.0 11.4 13 0 0 13 13 13 6 Ankyrin repeat FliT PF05400.13 PVD33496.1 - 0.3 11.9 3.1 14 6.6 0.5 4.3 5 0 0 5 5 5 0 Flagellar protein FliT Ank_4 PF13637.6 PVD33497.1 - 1e-10 41.9 0.1 0.026 15.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33497.1 - 7e-09 36.2 0.6 0.002 18.7 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33497.1 - 1.8e-05 24.7 0.0 45 5.1 0.0 6.2 7 0 0 7 7 7 0 Ankyrin repeat Ank PF00023.30 PVD33497.1 - 3.3e-05 24.1 0.1 6.8 7.3 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 PVD33497.1 - 0.00049 20.3 0.1 0.92 9.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 PVD33497.1 - 0.023 14.5 0.1 0.081 12.6 0.1 1.8 2 0 0 2 2 2 0 Shigella flexneri OspC protein Ank_4 PF13637.6 PVD33498.1 - 4.4e-102 333.3 68.6 2.2e-06 28.1 0.0 28.7 21 9 12 34 34 34 23 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33498.1 - 4.5e-101 329.6 49.8 1.6e-07 31.4 0.4 26.1 24 3 2 26 26 26 21 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33498.1 - 1e-98 324.1 49.4 6.9e-10 39.4 0.3 20.8 10 7 10 20 20 20 17 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33498.1 - 7.3e-72 228.7 50.1 0.00015 21.9 0.0 35.7 42 2 0 43 43 43 14 Ankyrin repeat Ank PF00023.30 PVD33498.1 - 2.8e-63 207.8 64.1 4.3e-05 23.8 0.0 31.9 39 0 0 39 39 39 16 Ankyrin repeat SOCS_box PF07525.16 PVD33498.1 - 0.0016 18.8 3.5 0.0051 17.1 3.5 1.9 1 0 0 1 1 1 1 SOCS box Peptidase_M16 PF00675.20 PVD33498.1 - 0.0081 16.1 0.3 17 5.4 0.0 3.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) MOR2-PAG1_C PF14225.6 PVD33498.1 - 0.0096 15.8 1.1 1.2 9.0 0.1 3.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal CspB_prodomain PF18425.1 PVD33498.1 - 0.18 11.8 0.0 0.69 10.0 0.0 2.0 1 0 0 1 1 1 0 Csp protease B prodomain Ank_2 PF12796.7 PVD33499.1 - 2.3e-15 56.9 4.1 7.7e-08 32.8 0.1 2.9 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33499.1 - 9.6e-13 48.4 2.0 3.1e-06 27.6 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33499.1 - 6.9e-11 42.2 13.7 0.00054 20.2 0.4 5.9 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33499.1 - 3.2e-09 36.3 6.1 0.14 12.8 0.0 5.9 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.30 PVD33499.1 - 3.2e-08 33.6 8.7 0.013 15.9 0.0 5.0 6 0 0 6 6 6 3 Ankyrin repeat CH_2 PF06294.11 PVD33499.1 - 0.025 14.7 0.1 3.6 7.8 0.1 2.9 2 1 0 2 2 2 0 CH-like domain in sperm protein Ank_2 PF12796.7 PVD33500.1 - 6.8e-37 125.9 12.5 0.00021 21.8 0.1 11.9 3 2 12 15 15 15 12 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33500.1 - 2.2e-36 123.5 10.9 9.1e-06 25.9 0.0 13.1 13 2 1 14 14 14 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33500.1 - 2.4e-31 107.7 14.2 0.01 16.4 0.1 14.4 8 4 6 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33500.1 - 4.3e-31 103.5 0.3 0.0016 18.8 0.0 15.5 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 PVD33500.1 - 5.5e-25 86.7 2.6 0.0024 18.2 0.0 11.9 12 0 0 12 12 12 6 Ankyrin repeat SOCS_box PF07525.16 PVD33500.1 - 9.2e-05 22.7 1.5 0.00021 21.5 1.5 1.7 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD33501.1 - 3.6e-57 190.0 29.0 6.2e-07 29.8 0.8 13.6 7 4 9 16 16 16 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33501.1 - 4.7e-55 184.1 30.4 5.6e-09 36.5 0.1 10.4 2 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33501.1 - 1.8e-49 165.2 22.5 2.4e-06 27.7 0.5 12.3 10 3 3 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33501.1 - 1.9e-43 141.4 18.0 0.00052 20.3 0.0 18.0 19 0 0 19 19 19 10 Ankyrin repeat Ank PF00023.30 PVD33501.1 - 4.1e-40 134.5 31.4 4.9e-05 23.6 0.0 17.7 19 0 0 19 19 19 9 Ankyrin repeat Shigella_OspC PF06128.11 PVD33501.1 - 0.00043 20.1 2.9 1.3 8.7 0.0 4.5 5 0 0 5 5 5 2 Shigella flexneri OspC protein Ank_4 PF13637.6 PVD33502.1 - 3.5e-15 56.2 0.2 0.00014 22.4 0.0 4.8 1 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33502.1 - 1.5e-13 50.7 0.7 1.5e-06 28.4 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33502.1 - 1.9e-10 40.0 0.1 4.4e-05 23.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 PVD33502.1 - 1.8e-08 34.9 0.1 0.00036 21.1 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33502.1 - 2.5e-05 24.5 0.7 0.011 16.1 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat PTCB-BRCT PF12738.7 PVD33502.1 - 0.041 13.8 0.2 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 twin BRCT domain Ank_2 PF12796.7 PVD33503.1 - 9.3e-94 308.2 39.7 7.5e-10 39.3 0.4 18.9 6 4 14 20 20 20 18 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33503.1 - 4.6e-93 304.0 33.4 5e-08 33.0 0.3 23.1 20 4 4 24 24 24 19 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33503.1 - 2.3e-82 270.4 37.2 5.8e-07 29.9 0.0 24.8 20 7 7 28 28 28 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33503.1 - 5.3e-68 216.9 26.0 0.00043 20.5 0.0 29.4 31 1 1 32 32 32 15 Ankyrin repeat Ank PF00023.30 PVD33503.1 - 3.7e-67 220.0 45.8 0.00025 21.3 0.1 28.4 31 1 1 32 32 32 16 Ankyrin repeat SOCS_box PF07525.16 PVD33503.1 - 5.2e-06 26.7 2.5 1.6e-05 25.2 2.5 1.8 1 0 0 1 1 1 1 SOCS box PHM7_cyt PF14703.6 PVD33503.1 - 0.14 12.4 0.2 0.27 11.4 0.2 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Ank_5 PF13857.6 PVD33504.1 - 2.1e-110 359.3 50.7 3.8e-08 33.4 0.1 25.8 23 3 4 27 27 27 19 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33504.1 - 1e-103 338.5 59.3 2.9e-11 43.6 0.1 28.5 18 8 10 30 30 30 25 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33504.1 - 4.4e-103 338.1 52.8 1.6e-09 38.2 1.0 21.0 6 4 18 24 24 24 23 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33504.1 - 3.8e-83 270.6 52.1 7.1e-05 23.1 0.0 30.1 30 1 1 31 31 31 18 Ankyrin repeat Ank_3 PF13606.6 PVD33504.1 - 1.3e-72 231.0 40.3 0.00087 19.6 0.0 33.0 37 0 0 37 37 37 15 Ankyrin repeat Shigella_OspC PF06128.11 PVD33504.1 - 5.8e-05 23.0 1.5 1.6 8.4 0.1 4.5 4 0 0 4 4 4 2 Shigella flexneri OspC protein Ank_4 PF13637.6 PVD33505.1 - 7.4e-84 275.1 41.9 7.2e-08 32.8 0.5 22.3 13 4 11 26 26 26 18 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33505.1 - 1.1e-78 259.8 40.9 1.7e-08 34.9 0.1 16.9 6 4 9 16 16 16 14 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33505.1 - 2.3e-75 247.6 33.1 4.6e-06 26.8 0.5 18.1 16 3 3 19 19 19 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33505.1 - 1.3e-62 200.3 27.3 0.00033 20.9 0.0 26.4 29 0 0 29 29 29 12 Ankyrin repeat Ank PF00023.30 PVD33505.1 - 1e-57 190.2 36.6 2.6e-05 24.4 0.0 25.1 25 2 0 25 25 25 13 Ankyrin repeat Shigella_OspC PF06128.11 PVD33505.1 - 1.2e-05 25.2 8.0 1.2 8.7 0.0 7.0 8 0 0 8 8 8 2 Shigella flexneri OspC protein SOCS_box PF07525.16 PVD33505.1 - 0.0002 21.6 3.9 0.00046 20.5 3.9 1.6 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 PVD33506.1 - 8.6e-91 297.3 68.4 4.8e-08 33.4 0.3 30.6 24 7 11 35 35 35 23 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33506.1 - 3.3e-90 296.8 60.7 7.2e-11 42.5 0.6 20.5 9 5 8 18 18 18 16 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD33506.1 - 4.6e-78 256.3 55.1 1.1e-06 28.8 0.0 24.8 22 4 3 26 26 26 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33506.1 - 6.2e-66 210.5 46.7 0.0012 19.2 0.0 28.6 32 0 0 32 32 32 14 Ankyrin repeat Ank PF00023.30 PVD33506.1 - 2.4e-64 211.1 67.3 0.00019 21.7 0.0 29.6 30 3 1 31 31 31 15 Ankyrin repeat RUN PF02759.19 PVD33506.1 - 0.086 12.8 0.6 2.9 7.8 0.2 3.4 4 0 0 4 4 4 0 RUN domain SOCS_box PF07525.16 PVD33506.1 - 0.1 13.0 5.3 0.073 13.4 1.9 2.4 2 0 0 2 2 2 0 SOCS box Myb_DNA-binding PF00249.31 PVD33507.1 - 6.2e-05 23.1 0.1 0.0002 21.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF5101 PF17031.5 PVD33507.1 - 0.0085 16.2 1.5 0.03 14.4 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) Sina PF03145.16 PVD33508.1 - 5.8e-84 281.0 0.1 5.8e-84 281.0 0.1 1.5 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 PVD33508.1 - 1e-05 25.3 6.7 1e-05 25.3 6.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD33508.1 - 0.13 12.1 15.5 0.065 13.1 12.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD33508.1 - 0.14 12.1 16.1 0.41 10.6 13.8 2.7 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD33508.1 - 0.14 12.2 7.7 0.57 10.2 7.5 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD33508.1 - 0.98 9.3 12.0 33 4.5 12.7 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD33508.1 - 1.2 9.1 10.9 3.8 7.5 10.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 PVD33508.1 - 3.2 8.3 11.1 6.2 7.4 11.1 1.6 1 0 0 1 1 1 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 PVD33508.1 - 9.6 6.5 15.7 0.29 11.3 8.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING WD40 PF00400.32 PVD33510.1 - 0.0037 18.1 0.9 6.6 7.8 0.4 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat PNPase_C PF12111.8 PVD33510.1 - 0.3 10.5 1.6 0.96 8.9 1.6 1.9 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal CUT PF02376.15 PVD33511.1 - 3.7e-32 110.3 0.5 6e-32 109.7 0.5 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 PVD33511.1 - 3.3e-11 42.9 0.7 7.2e-11 41.8 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD33511.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain GLTSCR1 PF15249.6 PVD33514.1 - 7.8e-25 87.3 0.8 7.8e-25 87.3 0.8 3.1 4 0 0 4 4 4 1 Conserved region of unknown function on GLTSCR protein Trypsin_2 PF13365.6 PVD33515.1 - 1.6e-25 90.7 0.2 7.1e-22 78.9 0.6 2.3 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 PVD33515.1 - 2.7e-06 27.3 0.1 6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Trypsin SIR2 PF02146.17 PVD33516.1 - 6.7e-52 176.0 0.0 1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PVD33516.1 - 0.022 14.5 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Asp PF00026.23 PVD33517.1 - 1.3e-121 405.9 0.0 1.5e-121 405.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PVD33517.1 - 2e-14 54.2 0.7 1.4e-06 28.6 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 PVD33517.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.12 PVD33517.1 - 5.9e-05 22.8 0.8 0.0001 22.1 0.8 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.6 PVD33517.1 - 0.023 15.3 0.1 1 10.0 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Tetraspanin PF00335.20 PVD33518.1 - 2.8e-51 174.5 10.5 3.2e-51 174.2 10.5 1.0 1 0 0 1 1 1 1 Tetraspanin family MBOAT PF03062.19 PVD33518.1 - 0.0072 15.7 0.6 0.0092 15.4 0.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SAM_PNT PF02198.16 PVD33522.1 - 1.6e-16 60.1 0.5 2.2e-16 59.6 0.5 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.22 PVD33523.1 - 1.9e-34 118.0 0.6 2.8e-34 117.4 0.6 1.3 1 0 0 1 1 1 1 Ets-domain MSA-2c PF12238.8 PVD33523.1 - 1.1 9.2 11.4 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c CDC50 PF03381.15 PVD33524.1 - 5.9e-52 176.9 11.2 1.2e-32 113.6 4.7 2.1 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family Neurensin PF14927.6 PVD33524.1 - 0.021 14.5 0.1 3.2 7.5 0.0 2.6 2 1 0 2 2 2 0 Neurensin InvH PF04741.12 PVD33524.1 - 0.12 12.3 0.4 2.1 8.3 0.2 2.6 2 1 0 2 2 2 0 InvH outer membrane lipoprotein DUF2336 PF10098.9 PVD33527.1 - 0.071 12.6 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) G8 PF10162.9 PVD33530.1 - 2.9e-45 153.3 0.4 1.7e-26 92.7 0.0 3.4 2 1 0 2 2 2 2 G8 domain WSC PF01822.19 PVD33530.1 - 4.1e-14 52.5 8.3 4.1e-14 52.5 8.3 2.3 2 0 0 2 2 2 1 WSC domain ILEI PF15711.5 PVD33530.1 - 8.6e-06 26.2 0.0 3.9e-05 24.0 0.0 2.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer Beta_helix PF13229.6 PVD33530.1 - 0.00016 21.5 6.3 0.00016 21.5 6.3 3.8 3 1 0 3 3 3 1 Right handed beta helix region WSC PF01822.19 PVD33531.1 - 6.8e-13 48.6 2.8 1.5e-12 47.5 2.8 1.6 1 0 0 1 1 1 1 WSC domain PARP PF00644.20 PVD33532.1 - 1.1e-23 83.8 0.1 4.3e-23 81.9 0.1 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Gal_Lectin PF02140.18 PVD33532.1 - 4.2e-10 39.9 2.0 1.5e-09 38.2 2.0 2.0 1 0 0 1 1 1 1 Galactose binding lectin domain Dus PF01207.17 PVD33533.1 - 0.1 11.7 1.0 0.17 11.0 0.2 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) SDF PF00375.18 PVD33534.1 - 1.4e-84 284.4 27.9 3.5e-84 283.1 27.9 1.6 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DEAD PF00270.29 PVD33534.1 - 3.2e-16 59.6 0.0 6.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD33534.1 - 3.8e-16 59.4 0.0 1.8e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD33534.1 - 4.8e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 PVD33534.1 - 0.12 11.7 0.3 0.27 10.5 0.1 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1043 PF06295.12 PVD33534.1 - 0.74 9.8 5.4 2 8.4 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF892 PF05974.12 PVD33534.1 - 1 9.3 3.7 2 8.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) GAS PF13851.6 PVD33534.1 - 1.4 8.2 8.2 3 7.1 8.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NDT80_PhoG PF05224.12 PVD33535.1 - 1.8e-24 87.0 0.9 1.8e-24 87.0 0.9 4.1 3 1 0 3 3 3 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 PVD33535.1 - 9.5e-22 75.9 1.8 2e-21 74.8 1.8 1.6 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 MRF_C2 PF13888.6 PVD33535.1 - 6e-10 39.2 0.1 2.9e-09 37.0 0.1 2.2 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 Peptidase_S74 PF13884.6 PVD33535.1 - 2.4e-09 37.4 0.2 5e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase SID-1_RNA_chan PF13965.6 PVD33535.1 - 0.02 13.3 1.5 0.034 12.6 1.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAM_1 PF00536.30 PVD33536.1 - 4.4e-26 91.1 0.6 2.3e-13 50.4 0.2 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD33536.1 - 1e-24 86.4 0.6 6.6e-10 39.0 0.1 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) DUF1664 PF07889.12 PVD33536.1 - 0.0034 17.4 3.1 0.0034 17.4 3.1 6.7 5 1 1 6 6 6 3 Protein of unknown function (DUF1664) DraK_HK_N PF18092.1 PVD33536.1 - 0.29 11.6 6.1 0.12 12.8 2.1 2.6 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain HTH_10 PF04967.12 PVD33536.1 - 6.5 6.6 7.0 3.6 7.5 0.2 3.6 3 0 0 3 3 3 0 HTH DNA binding domain DUF3967 PF13152.6 PVD33536.1 - 9.2 6.1 10.5 0.11 12.3 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) A_deaminase PF00962.22 PVD33537.1 - 2.8e-20 72.9 0.0 3.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 PVD33537.1 - 3.1e-05 24.2 0.0 5.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Ependymin PF00811.18 PVD33539.1 - 3.5e-06 27.3 0.3 7.8e-05 22.9 0.3 2.4 1 1 0 1 1 1 1 Ependymin DDE_Tnp_4 PF13359.6 PVD33540.1 - 2.8e-08 33.6 0.0 5.1e-08 32.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease CH PF00307.31 PVD33541.1 - 1.4e-77 256.9 0.0 3.8e-19 68.9 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD33541.1 - 2.1e-09 37.1 0.0 0.0031 17.3 0.0 3.6 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_7 PF13499.6 PVD33541.1 - 3.6e-09 36.9 0.2 1.6e-08 34.9 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD33541.1 - 4.1e-07 29.4 1.6 0.026 14.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PVD33541.1 - 5.4e-06 25.6 0.8 0.021 14.4 0.0 3.3 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 PVD33541.1 - 2.1e-05 23.8 0.6 0.21 11.1 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD33541.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Cu-binding_MopE PF11617.8 PVD33542.1 - 0.012 15.8 2.7 0.012 15.8 2.7 2.5 2 0 0 2 2 2 0 Putative metal-binding motif TMEMspv1-c74-12 PF11044.8 PVD33542.1 - 0.043 13.8 0.6 0.072 13.1 0.6 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TMEM154 PF15102.6 PVD33542.1 - 0.13 12.2 0.2 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 TMEM154 protein family RRM_1 PF00076.22 PVD33547.1 - 1e-38 130.9 3.0 2.6e-15 56.0 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 PVD33547.1 - 1.3e-21 76.7 0.0 2.9e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 PVD33547.1 - 1.8e-05 24.8 0.2 0.056 13.6 0.1 3.5 3 2 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 PVD33547.1 - 0.0073 16.1 0.1 0.59 10.0 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PVD33547.1 - 0.018 15.1 0.5 0.38 10.9 0.1 2.8 3 0 0 3 3 3 0 Limkain b1 RRM_8 PF11835.8 PVD33547.1 - 0.018 15.2 0.5 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 RRM-like domain RRM_5 PF13893.6 PVD33547.1 - 0.023 14.3 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 PVD33547.1 - 0.13 11.9 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 Sulfatase PF00884.23 PVD33548.1 - 3e-26 92.6 0.0 7.6e-26 91.2 0.0 1.7 1 1 0 1 1 1 1 Sulfatase DIRP PF06584.13 PVD33549.1 - 7.5e-43 145.0 0.5 7.5e-43 145.0 0.5 2.6 3 0 0 3 3 3 1 DIRP DUF1043 PF06295.12 PVD33549.1 - 0.15 12.1 1.2 0.31 11.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) NACHT PF05729.12 PVD33550.1 - 6.4e-12 45.7 0.0 1.6e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 PVD33550.1 - 1.4e-08 35.3 0.5 2.1e-07 31.5 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain WD40 PF00400.32 PVD33550.1 - 3.5e-05 24.5 2.3 0.0048 17.7 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ATPase_2 PF01637.18 PVD33550.1 - 0.00018 21.5 0.0 0.00056 19.9 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PVD33550.1 - 0.00029 21.1 0.1 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain APAF1_C PF17908.1 PVD33550.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 APAF-1 helical domain KAP_NTPase PF07693.14 PVD33550.1 - 0.034 13.4 1.7 0.073 12.3 0.1 2.2 2 1 1 3 3 3 0 KAP family P-loop domain AAA PF00004.29 PVD33550.1 - 0.13 12.7 0.0 0.87 10.0 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PALB2_WD40 PF16756.5 PVD33550.1 - 0.28 10.1 2.4 25 3.6 0.0 4.3 5 0 0 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 PVD33550.1 - 0.83 8.2 3.3 1.2 7.8 0.6 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DENN PF02141.21 PVD33551.1 - 1.5e-44 152.2 0.3 2.4e-44 151.5 0.3 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PVD33551.1 - 3.8e-18 66.0 0.8 8.4e-18 64.9 0.8 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 PVD33551.1 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 PVD33551.1 - 0.0026 17.7 0.1 0.0041 17.1 0.1 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis AMP-binding PF00501.28 PVD33552.1 - 4.8e-64 216.5 0.0 2.4e-48 164.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 PVD33552.1 - 7.4e-22 77.0 1.6 1.3e-21 76.2 1.6 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 PVD33552.1 - 4.9e-19 69.1 1.5 1.1e-18 68.0 1.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-TRAF PF02176.18 PVD33553.1 - 2e-16 60.4 31.5 1.7e-07 31.8 9.1 4.9 1 1 3 4 4 4 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 PVD33553.1 - 1.5e-11 44.0 5.5 1.5e-11 44.0 5.5 4.1 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD33553.1 - 1.2e-09 37.8 5.2 1.2e-09 37.8 5.2 4.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD33553.1 - 4.6e-09 36.5 6.2 4.6e-09 36.5 6.2 4.5 3 1 3 6 6 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD33553.1 - 1.9e-07 31.0 6.3 1.9e-07 31.0 6.3 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD33553.1 - 1.1e-06 28.4 4.4 1.1e-06 28.4 4.4 4.1 4 1 1 5 5 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD33553.1 - 2.4e-06 27.6 4.3 2.4e-06 27.6 4.3 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 PVD33553.1 - 1.8e-05 24.8 0.2 0.0001 22.4 0.0 2.4 2 1 1 3 3 2 1 U-box domain zf-TRAF_2 PF15965.5 PVD33553.1 - 2.5e-05 24.7 29.5 0.11 13.0 7.6 3.8 1 1 2 3 3 3 3 TRAF-like zinc-finger zf-rbx1 PF12678.7 PVD33553.1 - 6.8e-05 23.1 3.1 6.8e-05 23.1 3.1 3.8 5 0 0 5 5 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD33553.1 - 0.00023 21.1 4.2 0.00023 21.1 4.2 4.3 4 1 1 5 5 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD33553.1 - 0.00047 20.0 3.9 0.00047 20.0 3.9 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PVD33553.1 - 0.004 16.9 3.1 0.004 16.9 3.1 3.6 4 0 0 4 4 4 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 PVD33553.1 - 0.0059 16.3 2.8 0.024 14.4 2.8 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 PVD33553.1 - 0.0074 16.1 2.1 0.0074 16.1 2.1 4.1 4 0 0 4 4 4 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PVD33553.1 - 0.0075 16.3 0.5 0.0075 16.3 0.5 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ACC PF17848.1 PVD33553.1 - 0.014 15.4 12.9 0.11 12.5 0.1 4.4 5 0 0 5 5 3 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 PVD33553.1 - 0.051 13.0 0.1 0.051 13.0 0.1 3.6 5 0 0 5 5 3 0 zinc-ribbon domain CR6_interact PF10147.9 PVD33553.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 BLOC1_2 PF10046.9 PVD33553.1 - 0.072 13.4 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF371 PF04027.13 PVD33553.1 - 0.088 12.8 0.6 0.34 10.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF371) Interferon PF00143.19 PVD33553.1 - 0.23 11.6 6.9 0.59 10.3 1.3 2.4 2 0 0 2 2 2 0 Interferon alpha/beta domain ADK_lid PF05191.14 PVD33553.1 - 0.32 11.0 3.0 0.45 10.5 1.0 2.4 2 0 0 2 2 1 0 Adenylate kinase, active site lid PyrI_C PF02748.15 PVD33553.1 - 1.2 9.1 5.9 2 8.4 0.9 2.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain YgaB PF14182.6 PVD33553.1 - 2.2 8.7 8.1 1.5 9.3 2.3 2.5 2 0 0 2 2 2 0 YgaB-like protein bZIP_2 PF07716.15 PVD33553.1 - 2.6 8.2 4.7 5.4 7.2 4.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper A2L_zn_ribbon PF08792.10 PVD33553.1 - 4 7.3 10.2 4.1 7.2 0.1 3.7 3 0 0 3 3 3 0 A2L zinc ribbon domain LRR_8 PF13855.6 PVD33554.1 - 3.7e-45 151.5 46.9 5e-13 48.6 0.1 7.3 5 2 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PVD33554.1 - 1.5e-18 66.5 44.9 0.00036 20.9 1.6 8.7 5 3 2 9 9 9 7 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD33554.1 - 2e-18 66.8 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD33554.1 - 1.1e-17 64.2 10.5 9.2e-08 32.1 0.7 4.2 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 PVD33554.1 - 6.6e-16 59.0 0.0 1.1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD33554.1 - 1.6e-05 24.4 18.7 0.0013 18.3 0.5 4.6 1 1 4 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 PVD33554.1 - 0.053 14.1 37.0 2.3 9.1 0.4 11.7 11 3 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD33554.1 - 6.7 7.0 31.2 6.2 7.1 0.2 9.6 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 PVD33555.1 - 1.9e-41 139.7 53.1 3.2e-12 46.0 0.5 7.5 4 3 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PVD33555.1 - 1.1e-19 70.1 55.5 0.0005 20.4 3.8 10.1 7 3 3 11 11 11 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD33555.1 - 6e-19 68.3 5.5 1.8e-08 34.4 0.7 3.5 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD33555.1 - 3.1e-07 30.1 22.1 0.31 10.5 0.8 5.4 1 1 3 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.6 PVD33556.1 - 1.4e-43 146.5 42.4 1.3e-11 44.1 0.0 7.2 4 3 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PVD33556.1 - 1.2e-18 66.9 45.0 0.00095 19.5 1.1 9.7 3 3 7 11 11 11 8 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD33556.1 - 3.5e-18 66.0 0.0 6.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD33556.1 - 4.3e-18 65.5 7.7 3.3e-08 33.6 0.7 3.7 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 PVD33556.1 - 7.3e-16 58.8 0.0 1.3e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 PVD33556.1 - 1.3e-05 24.7 19.4 0.03 13.8 0.5 4.3 1 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 PVD33556.1 - 0.72 10.6 32.8 41 5.3 0.2 11.5 12 2 0 12 12 12 0 Leucine Rich Repeat TIR PF01582.20 PVD33557.1 - 4.3e-37 127.6 0.0 2.6e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 TIR domain TIR_2 PF13676.6 PVD33557.1 - 3.8e-33 114.6 0.0 1e-15 58.4 0.0 2.6 2 0 0 2 2 2 2 TIR domain LRR_8 PF13855.6 PVD33557.1 - 3.6e-18 65.1 17.5 3.3e-07 30.0 1.3 5.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PVD33557.1 - 1.5e-12 47.5 18.1 0.015 15.7 1.7 5.9 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) Cadherin_C_2 PF16492.5 PVD33557.1 - 8.6e-05 23.2 0.1 0.68 10.7 0.0 2.8 2 0 0 2 2 2 2 Cadherin cytoplasmic C-terminal LRR_5 PF13306.6 PVD33557.1 - 0.0001 22.3 1.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Amnionless PF14828.6 PVD33557.1 - 0.00086 18.2 0.1 0.35 9.6 0.0 2.2 2 0 0 2 2 2 2 Amnionless CopD PF05425.13 PVD33557.1 - 0.0012 19.2 0.6 0.82 10.1 0.1 2.5 2 0 0 2 2 2 1 Copper resistance protein D HemY_N PF07219.13 PVD33557.1 - 0.0019 18.4 2.0 0.83 9.9 0.1 2.5 2 0 0 2 2 2 2 HemY protein N-terminus RBP_receptor PF14752.6 PVD33557.1 - 0.03 12.9 2.1 2 6.9 0.1 2.1 2 0 0 2 2 2 0 Retinol binding protein receptor Presenilin PF01080.17 PVD33557.1 - 0.041 12.7 1.8 0.58 8.9 0.0 2.2 2 0 0 2 2 2 0 Presenilin DC_STAMP PF07782.13 PVD33557.1 - 0.048 13.5 1.7 0.69 9.7 0.3 2.3 2 0 0 2 2 2 0 DC-STAMP-like protein Trp_oprn_chp PF09534.10 PVD33557.1 - 0.056 13.2 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4229 PF14012.6 PVD33557.1 - 0.068 13.3 6.2 3.6 7.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF2207 PF09972.9 PVD33557.1 - 0.078 11.7 0.1 2.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LRR_9 PF14580.6 PVD33557.1 - 0.11 12.0 0.4 3.8 7.0 0.3 2.9 2 1 1 3 3 3 0 Leucine-rich repeat DUF3357 PF11837.8 PVD33557.1 - 0.15 12.5 0.1 20 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) LRR_1 PF00560.33 PVD33557.1 - 0.25 12.0 19.0 1.8 9.4 0.4 6.5 6 1 0 6 6 5 0 Leucine Rich Repeat Transgly_assoc PF04226.13 PVD33557.1 - 0.47 10.7 3.7 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein DUF2701 PF10857.8 PVD33557.1 - 0.86 9.7 7.0 8.8 6.4 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) SLATT_4 PF18186.1 PVD33557.1 - 2.5 7.7 3.8 0.64 9.6 0.6 1.6 2 0 0 2 2 1 0 SMODS and SLOG-associating 2TM effector domain family 4 IlvB_leader PF08049.11 PVD33557.1 - 6.5 6.8 8.3 17 5.4 1.0 2.5 2 0 0 2 2 2 0 IlvB leader peptide LRR_6 PF13516.6 PVD33557.1 - 7.1 7.0 15.3 11 6.4 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 PVD33558.1 - 7e-25 86.6 27.0 1.6e-09 37.4 5.5 4.5 2 1 1 4 4 4 4 Leucine rich repeat TIR PF01582.20 PVD33558.1 - 2.4e-18 66.5 0.0 4.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD33558.1 - 3.8e-16 59.7 0.0 8.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD33558.1 - 1.3e-08 34.8 0.2 3.3e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD33558.1 - 9.4e-07 29.1 25.8 0.0073 16.7 0.6 6.0 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD33558.1 - 0.21 11.1 8.2 0.54 9.7 1.1 3.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 PVD33558.1 - 1.7 9.5 18.3 1.7e+02 3.4 1.3 7.9 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD33559.1 - 1.1e-43 146.8 26.1 1.5e-13 50.3 0.1 7.4 3 2 7 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 PVD33559.1 - 7.2e-18 64.8 8.4 1.5e-09 37.9 1.2 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 PVD33559.1 - 4.9e-17 62.3 0.0 9.2e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD33559.1 - 5.7e-15 56.0 0.0 1.5e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD33559.1 - 1.2e-14 54.1 36.6 2.6e-05 24.5 1.4 9.4 3 3 5 11 11 11 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD33559.1 - 2e-06 27.4 14.7 0.015 14.8 0.5 4.6 2 1 3 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 PVD33559.1 - 0.18 12.5 26.2 3.6 8.5 0.1 8.9 9 3 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD33560.1 - 8.3e-28 95.9 16.8 2.7e-14 52.7 0.9 3.7 2 1 2 4 4 4 4 Leucine rich repeat TIR PF01582.20 PVD33560.1 - 2.7e-19 69.6 0.0 5.1e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD33560.1 - 8.6e-17 61.8 0.0 1.5e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD33560.1 - 4e-09 36.6 14.4 0.0036 17.7 0.1 4.7 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD33560.1 - 1.8e-06 27.9 0.1 3.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD33560.1 - 0.00011 22.2 9.8 17 6.4 0.0 6.7 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD33560.1 - 0.075 12.5 0.1 0.25 10.9 0.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 PVD33560.1 - 0.28 11.3 16.9 11 6.4 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 PVD33561.1 - 4.1e-42 141.8 47.0 2.2e-12 46.5 0.2 7.3 4 3 3 7 7 7 7 Leucine rich repeat TIR PF01582.20 PVD33561.1 - 7.7e-19 68.2 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD33561.1 - 1e-17 63.9 51.9 0.00012 22.4 0.3 9.7 4 3 8 12 12 12 11 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD33561.1 - 3.2e-16 60.0 0.0 6.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD33561.1 - 3.8e-15 56.0 11.5 5.5e-07 29.6 0.7 3.4 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD33561.1 - 8.2e-06 25.4 19.9 0.093 12.2 0.4 5.2 1 1 4 6 6 6 6 Leucine-rich repeat LRR_8 PF13855.6 PVD33562.1 - 1.5e-45 152.8 44.4 7.2e-14 51.3 1.3 6.6 3 1 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PVD33562.1 - 3.8e-21 74.8 38.8 0.0002 21.7 0.1 9.1 3 3 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD33562.1 - 5.8e-16 58.6 3.9 4.5e-08 33.1 0.1 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD33562.1 - 6.7e-07 29.0 13.7 0.089 12.3 0.2 4.8 1 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 PVD33562.1 - 0.051 14.1 31.3 15 6.7 0.1 10.0 11 1 0 11 11 11 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD33563.1 - 7.6e-12 44.8 5.2 7.6e-12 44.8 5.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_5 PF13306.6 PVD33563.1 - 7.1e-09 35.7 2.9 1e-08 35.2 2.9 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD33563.1 - 0.024 14.1 1.0 0.053 13.0 1.0 1.4 1 1 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 PVD33563.1 - 0.32 11.5 12.9 0.36 11.3 3.3 3.0 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD33564.1 - 4.1e-20 71.3 1.5 1.5e-15 56.7 0.2 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD33564.1 - 6.5e-14 51.8 2.6 1.1e-06 28.9 0.1 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD33564.1 - 2.2e-08 34.1 0.1 7.6e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD33564.1 - 3.3e-07 29.9 0.5 0.82 10.5 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD33564.1 - 9e-05 22.0 2.1 0.00042 19.9 2.3 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PVD33564.1 - 0.056 13.5 8.3 82 3.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 PVD33565.1 - 5.7e-28 96.5 5.8 9.9e-14 50.9 0.1 4.3 1 1 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.6 PVD33565.1 - 2.4e-11 43.7 0.5 1.2e-10 41.5 0.5 2.0 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD33565.1 - 1.8e-10 40.9 3.0 8.9e-05 22.8 0.5 4.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD33565.1 - 0.00023 21.2 0.6 26 5.9 0.1 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 PVD33565.1 - 0.00097 18.7 0.5 0.0024 17.4 0.5 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PVD33565.1 - 0.034 14.2 1.8 73 3.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat TPKR_C2 PF16920.5 PVD33565.1 - 0.054 13.6 0.3 0.17 12.0 0.3 1.9 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain PAX PF00292.18 PVD33567.1 - 1.8e-70 234.6 0.9 3e-70 234.0 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 PVD33567.1 - 3.4e-22 78.1 3.0 9.4e-22 76.6 3.0 1.8 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 PVD33567.1 - 1.2e-05 25.8 0.5 0.02 15.5 0.0 3.4 3 0 0 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 PVD33567.1 - 0.0012 18.5 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 PVD33567.1 - 0.01 15.4 0.1 0.044 13.4 0.0 2.1 3 0 0 3 3 3 0 InsA C-terminal domain Homeobox_KN PF05920.11 PVD33567.1 - 0.085 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Ank_2 PF12796.7 PVD33570.1 - 9.7e-35 119.0 1.2 6.8e-15 55.4 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD33570.1 - 1.3e-32 111.7 9.4 1.5e-08 35.0 0.2 6.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33570.1 - 1.3e-29 101.9 4.4 1.4e-08 34.9 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD33570.1 - 7e-28 95.8 2.4 1.2e-05 25.5 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 PVD33570.1 - 7.8e-26 87.3 0.0 0.00031 21.0 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat SAM_1 PF00536.30 PVD33570.1 - 1.2e-25 89.7 0.0 6.2e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD33570.1 - 3e-21 75.3 0.0 4.5e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PID PF00640.23 PVD33570.1 - 1.2e-18 67.5 0.7 1.2e-18 67.5 0.7 2.3 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD33570.1 - 6.1e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 PVD33570.1 - 0.00052 19.9 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YhhN PF07947.14 PVD33571.1 - 1.7e-37 128.8 20.9 2.2e-37 128.4 20.9 1.2 1 0 0 1 1 1 1 YhhN family TAFII28 PF04719.14 PVD33572.1 - 1.1e-38 131.2 0.1 1.1e-38 131.2 0.1 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 PVD33572.1 - 5.8e-06 26.5 0.0 1.6e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Period_C PF12114.8 PVD33572.1 - 0.0034 17.0 16.7 0.0065 16.1 16.6 1.5 1 1 1 2 2 2 1 Period protein 2/3C-terminal region CDC45 PF02724.14 PVD33572.1 - 0.0058 15.0 11.5 0.0054 15.1 11.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Pex14_N PF04695.13 PVD33572.1 - 0.014 16.1 3.6 0.025 15.2 3.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 PVD33572.1 - 0.074 12.3 6.0 0.076 12.2 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 PVD33572.1 - 0.095 11.5 6.8 0.11 11.3 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein REC114-like PF15165.6 PVD33572.1 - 0.13 12.0 5.9 0.19 11.5 5.9 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like SOBP PF15279.6 PVD33572.1 - 0.16 12.5 10.8 0.17 12.4 10.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 PVD33572.1 - 0.22 10.2 14.4 0.28 9.9 14.4 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 PVD33572.1 - 0.27 10.1 12.7 0.29 9.9 12.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 PVD33572.1 - 0.27 9.8 11.4 0.3 9.7 11.4 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4614 PF15391.6 PVD33572.1 - 0.3 11.0 14.3 0.4 10.7 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ORC6 PF05460.13 PVD33572.1 - 0.59 9.3 13.7 0.77 9.0 13.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 PVD33572.1 - 0.85 8.2 7.5 0.9 8.2 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 PVD33572.1 - 3.1 8.2 16.7 8.6 6.8 16.8 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 PVD33572.1 - 4.3 6.2 9.1 5.1 6.0 9.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 PVD33572.1 - 4.4 6.0 17.6 5.2 5.7 17.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 PVD33572.1 - 4.7 5.2 14.8 5.4 5.0 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 PVD33572.1 - 6.4 6.2 12.2 8.9 5.8 12.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Menin PF05053.13 PVD33572.1 - 7.1 4.9 11.8 8.9 4.5 11.8 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 PVD33573.1 - 8.5e-64 215.4 0.1 6.2e-63 212.6 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33573.1 - 9e-31 107.1 1.9 1e-21 77.4 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 PVD33573.1 - 2e-06 28.4 0.8 1.4e-05 25.7 0.1 2.5 3 0 0 3 3 3 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 PVD33573.1 - 4.1e-06 26.0 0.1 6.1e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD33573.1 - 2.6e-05 23.7 0.3 0.002 17.5 0.1 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PVD33573.1 - 0.00015 21.2 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD33573.1 - 0.00078 19.4 0.2 0.058 13.3 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PVD33573.1 - 0.047 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 PVD33573.1 - 0.21 11.1 1.9 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Nckap1 PF09735.9 PVD33574.1 - 0 1436.6 26.2 0 1435.9 26.2 1.3 1 0 0 1 1 1 1 Membrane-associated apoptosis protein 7tm_1 PF00001.21 PVD33574.1 - 6.8e-11 42.0 24.4 2.1e-10 40.4 24.0 2.1 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) MSA-2c PF12238.8 PVD33574.1 - 0.17 11.9 0.9 0.46 10.5 0.9 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4734 PF15881.5 PVD33575.1 - 0.085 13.0 0.3 0.84 9.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) HNOB PF07700.15 PVD33577.1 - 6.7e-58 195.3 0.0 8.9e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 Haem-NO-binding INCENP_N PF12178.8 PVD33577.1 - 0.12 12.4 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Guanylate_cyc PF00211.20 PVD33578.1 - 3.7e-67 225.5 0.7 6.1e-67 224.8 0.7 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD33578.1 - 3.1e-40 138.0 0.3 7.3e-40 136.8 0.3 1.6 1 0 0 1 1 1 1 Heme NO binding associated TFIIA PF03153.13 PVD33578.1 - 2.9 7.8 11.4 4.9 7.0 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-U1 PF06220.12 PVD33579.1 - 7.5e-22 76.8 8.5 1e-21 76.4 8.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 PVD33579.1 - 0.43 11.0 4.7 4.3 7.9 4.7 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD33579.1 - 2.1 8.7 10.7 22 5.5 10.7 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Nup160 PF11715.8 PVD33580.1 - 3.9e-58 197.4 0.0 5e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD33580.1 - 0.0084 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Dimer_Tnp_hAT PF05699.14 PVD33581.1 - 0.00029 20.6 0.8 0.00093 18.9 0.0 2.3 3 1 0 3 3 3 1 hAT family C-terminal dimerisation region Use1 PF09753.9 PVD33581.1 - 0.22 11.2 9.4 0.31 10.7 9.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Coiled-coil_56 PF09813.9 PVD33581.1 - 0.54 10.3 3.9 0.16 12.0 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 HLH PF00010.26 PVD33583.1 - 7.3e-11 41.9 0.1 3.6e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CD225 PF04505.12 PVD33584.1 - 3.6e-21 75.1 1.4 6.9e-21 74.2 1.4 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CD225 PF04505.12 PVD33585.1 - 4e-21 74.9 0.8 5.9e-21 74.4 0.6 1.5 1 1 0 1 1 1 1 Interferon-induced transmembrane protein Engrail_1_C_sig PF10525.9 PVD33585.1 - 0.2 10.9 0.3 0.37 10.1 0.3 1.4 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain CD225 PF04505.12 PVD33586.1 - 6.8e-18 64.6 3.1 1e-17 64.0 3.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein VMA21 PF09446.10 PVD33586.1 - 0.019 15.1 0.3 0.019 15.1 0.3 1.7 2 0 0 2 2 2 0 VMA21-like domain DUF2269 PF10027.9 PVD33586.1 - 0.035 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) CD225 PF04505.12 PVD33587.1 - 2.5e-20 72.3 1.1 3.5e-20 71.9 0.8 1.4 1 1 0 1 1 1 1 Interferon-induced transmembrane protein DUF2269 PF10027.9 PVD33587.1 - 0.037 14.1 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Engrail_1_C_sig PF10525.9 PVD33587.1 - 0.17 11.1 0.3 0.33 10.2 0.3 1.5 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain CD225 PF04505.12 PVD33588.1 - 3.7e-41 139.1 14.8 1.3e-18 66.9 1.1 3.6 4 0 0 4 4 4 3 Interferon-induced transmembrane protein DUF1771 PF08590.10 PVD33588.1 - 0.00087 19.6 2.4 6.1 7.3 0.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1771) Calc_CGRP_IAPP PF00214.19 PVD33588.1 - 0.0027 18.1 0.3 0.98 9.8 0.0 2.3 2 0 0 2 2 2 2 Calcitonin / CGRP / IAPP family DUF2269 PF10027.9 PVD33588.1 - 0.08 13.0 0.8 11 6.0 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF3938 PF13074.6 PVD33588.1 - 0.14 12.4 0.7 4 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) CD225 PF04505.12 PVD33589.1 - 1.2e-19 70.2 1.1 2.2e-19 69.4 1.1 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CD225 PF04505.12 PVD33590.1 - 1e-18 67.2 2.3 1.8e-18 66.4 2.0 1.6 1 1 0 1 1 1 1 Interferon-induced transmembrane protein 7TM-7TMR_HD PF07698.11 PVD33590.1 - 0.033 13.9 1.1 0.046 13.5 1.1 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase CD225 PF04505.12 PVD33591.1 - 4.7e-17 61.9 0.3 7.4e-17 61.3 0.3 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4490 PF14892.6 PVD33591.1 - 0.0088 16.1 0.6 0.017 15.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) PMP1_2 PF08114.11 PVD33591.1 - 0.35 10.6 0.1 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 ATPase proteolipid family Ald_Xan_dh_C2 PF02738.18 PVD33592.1 - 2.3e-119 399.3 0.3 2e-68 231.3 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 PVD33592.1 - 2.5e-26 91.5 0.3 8.8e-26 89.7 0.1 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 PVD33592.1 - 4.8e-26 91.3 0.1 2.2e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PVD33592.1 - 9.8e-19 67.7 0.0 2.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33592.1 - 3.2e-18 65.8 0.0 9e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PVD33592.1 - 0.00067 19.6 2.1 0.00086 19.2 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PknG_rubred PF16919.5 PVD33592.1 - 5.1 7.3 5.5 0.65 10.2 0.7 1.9 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Ric8 PF10165.9 PVD33593.1 - 1.7e-120 403.2 2.6 2.2e-120 402.8 2.6 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn A2L_zn_ribbon PF08792.10 PVD33593.1 - 2.3 8.0 8.9 5.2 6.9 8.9 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain WW PF00397.26 PVD33594.1 - 2e-14 53.4 19.1 1.6e-07 31.2 5.0 2.5 2 0 0 2 2 2 2 WW domain Ald_Xan_dh_C2 PF02738.18 PVD33595.1 - 0 1150.6 15.5 1.5e-132 442.8 0.0 6.3 3 2 1 4 4 4 4 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 PVD33595.1 - 2.7e-77 254.8 12.9 3.8e-26 90.9 0.2 4.9 4 0 0 4 4 4 3 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 PVD33595.1 - 1.3e-63 212.2 0.0 1.9e-22 79.7 0.0 3.5 3 0 0 3 3 3 3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 PVD33595.1 - 2.3e-46 156.2 0.0 1.5e-14 54.0 0.0 4.2 4 0 0 4 4 4 3 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 PVD33595.1 - 7.3e-33 113.7 0.0 1.3e-14 54.3 0.0 4.6 3 1 0 3 3 3 3 FAD binding domain in molybdopterin dehydrogenase Fer2 PF00111.27 PVD33595.1 - 2.8e-11 43.2 5.2 0.00091 19.1 0.4 4.6 3 0 0 3 3 3 2 2Fe-2S iron-sulfur cluster binding domain DUF2387 PF09526.10 PVD33595.1 - 3e-05 24.1 9.5 0.11 12.6 0.1 4.6 4 0 0 4 4 4 2 Probable metal-binding protein (DUF2387) Fer2_4 PF13510.6 PVD33595.1 - 0.014 15.4 7.1 2.5 8.2 0.5 4.2 3 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain ChlI PF13541.6 PVD33595.1 - 0.065 13.1 0.0 14 5.5 0.0 2.8 3 0 0 3 3 3 0 Subunit ChlI of Mg-chelatase PilS PF08805.11 PVD33595.1 - 0.092 12.6 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 PilS N terminal Ald_Xan_dh_C2 PF02738.18 PVD33596.1 - 8.4e-131 437.1 0.0 1.4e-130 436.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 PVD33596.1 - 1.1e-23 83.0 0.4 3.5e-23 81.4 0.4 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 PVD33596.1 - 4.7e-23 81.8 0.0 8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33596.1 - 7.3e-19 67.9 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 PVD33596.1 - 5.4e-14 52.5 0.0 1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 PVD33596.1 - 0.0024 17.8 0.6 0.0024 17.8 0.6 2.8 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 PVD33597.1 - 5e-93 312.4 0.2 8.3e-47 159.9 0.0 3.3 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PVD33597.1 - 1.7e-24 86.5 0.0 2.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33597.1 - 4.6e-20 71.7 0.0 9.6e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 PVD33597.1 - 4.9e-19 68.7 0.0 8.7e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD33597.1 - 6e-08 32.6 0.0 3.2e-07 30.3 0.0 2.2 1 1 1 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 PVD33597.1 - 0.00071 19.5 0.6 0.00071 19.5 0.6 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 PVD33597.1 - 0.19 11.8 0.6 0.5 10.4 0.6 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2387 PF09526.10 PVD33597.1 - 0.28 11.4 0.7 0.68 10.1 0.7 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 PVD33597.1 - 0.44 10.5 2.2 1.4 8.9 2.2 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ald_Xan_dh_C2 PF02738.18 PVD33598.1 - 4.4e-142 474.3 0.0 6e-142 473.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PVD33598.1 - 1.6e-24 86.3 0.0 3e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD33598.1 - 3.5e-19 68.6 0.7 1.5e-18 66.5 0.6 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PVD33598.1 - 5.4e-19 68.3 0.0 1.9e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 PVD33598.1 - 8.4e-17 61.4 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2 PF00111.27 PVD33598.1 - 0.0026 17.7 0.7 0.0026 17.7 0.7 3.0 4 0 0 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 PVD33599.1 - 1.3e-143 479.4 0.0 1.8e-143 479.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PVD33599.1 - 6.6e-27 94.0 0.0 1.6e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD33599.1 - 1.6e-18 66.5 0.1 3.9e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 PVD33599.1 - 9.9e-07 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33599.1 - 3.9e-05 23.8 0.2 0.0004 20.5 0.1 2.5 1 1 1 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PVD33599.1 - 8.1e-05 22.5 0.5 0.00076 19.4 0.2 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF2387 PF09526.10 PVD33599.1 - 0.037 14.2 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ald_Xan_dh_C2 PF02738.18 PVD33600.1 - 5e-107 358.6 0.0 5.6e-74 249.6 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PVD33600.1 - 2.2e-25 89.1 0.0 4.1e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PVD33600.1 - 5.5e-25 88.1 0.0 1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 PVD33600.1 - 3.3e-07 30.2 0.1 8.7e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 PVD33600.1 - 0.00015 21.6 1.0 0.0011 18.9 0.3 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CO_deh_flav_C PF03450.17 PVD33600.1 - 0.00044 20.4 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain DUF2387 PF09526.10 PVD33600.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ald_Xan_dh_C2 PF02738.18 PVD33601.1 - 8.2e-97 324.9 0.1 1.7e-46 158.9 0.0 3.4 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 PVD33601.1 - 1.3e-24 86.0 0.3 2.9e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 PVD33601.1 - 1.6e-24 86.4 0.0 2.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PVD33601.1 - 5.5e-24 84.8 0.0 1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33601.1 - 3.1e-14 53.0 0.0 9.2e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PVD33601.1 - 0.00057 19.8 0.2 0.00057 19.8 0.2 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 PVD33601.1 - 0.11 12.6 0.3 0.34 11.0 0.3 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-C2H2 PF00096.26 PVD33602.1 - 9.7e-32 107.7 68.8 0.001 19.4 1.3 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33602.1 - 1.3e-20 72.3 68.5 0.021 15.7 1.6 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD33602.1 - 2.4e-14 53.0 64.6 0.00024 21.4 0.3 10.3 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_8 PF15909.5 PVD33602.1 - 8.9e-10 38.8 33.8 3.3e-05 24.1 2.7 5.4 1 1 4 5 5 5 4 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 PVD33602.1 - 6.7e-06 26.4 27.7 1.2 9.2 0.8 7.1 4 2 3 7 7 7 6 Aberrant zinc-finger zf-C2H2_6 PF13912.6 PVD33602.1 - 0.0026 17.7 0.2 0.0026 17.7 0.2 6.2 7 0 0 7 7 7 2 C2H2-type zinc finger MFS_1 PF07690.16 PVD33603.1 - 2.9e-05 23.2 3.2 3.5e-05 22.9 3.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Syndecan PF01034.20 PVD33603.1 - 0.013 15.4 0.5 0.021 14.7 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain DUF3487 PF11990.8 PVD33603.1 - 0.032 14.1 0.9 0.043 13.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF2964 PF11177.8 PVD33603.1 - 0.11 12.7 3.6 0.19 11.9 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Insulin_TMD PF17870.1 PVD33603.1 - 0.18 11.9 1.5 0.3 11.2 1.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Phage_holin_3_6 PF07332.11 PVD33603.1 - 0.41 10.7 7.5 0.19 11.8 5.6 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP1G1_PLM_MAT8 PF02038.16 PVD33603.1 - 1.6 8.2 4.4 7.2 6.1 2.3 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family SH3_2 PF07653.17 PVD33604.1 - 2.5e-23 81.5 1.6 5.2e-11 42.1 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 PVD33604.1 - 5.5e-20 70.7 0.1 1.3e-14 53.5 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 PVD33604.1 - 1.2e-16 60.6 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 PVD33604.1 - 3.1e-14 52.6 0.3 1.8e-08 34.1 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 PVD33604.1 - 0.00095 19.6 0.0 0.009 16.4 0.0 2.3 3 0 0 3 3 3 1 Helically-extended SH3 domain Sugar_tr PF00083.24 PVD33605.1 - 6.9e-17 61.4 5.6 6.9e-17 61.4 5.6 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD33605.1 - 1.9e-11 43.5 27.2 5.8e-10 38.6 21.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PDGLE PF13190.6 PVD33605.1 - 0.7 9.8 0.0 0.7 9.8 0.0 2.4 3 0 0 3 3 3 0 PDGLE domain NAD_binding_5 PF07994.12 PVD33606.1 - 1.7e-143 477.9 0.0 2e-143 477.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PVD33606.1 - 2.1e-48 163.1 0.2 4.9e-48 161.9 0.2 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 PVD33608.1 - 1.4e-144 481.4 0.0 1.8e-144 481.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PVD33608.1 - 7.7e-49 164.5 0.1 1.8e-48 163.3 0.1 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase CLIP_SPH_mas PF18398.1 PVD33608.1 - 0.14 12.6 0.1 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade DNA_pol_B PF00136.21 PVD33609.1 - 4.9e-148 493.6 0.1 8.5e-148 492.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PVD33609.1 - 1.5e-83 280.8 0.0 2.3e-83 280.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PVD33609.1 - 1.1e-19 70.6 7.4 2.8e-19 69.4 7.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 PVD33609.1 - 0.00014 20.9 0.1 0.00046 19.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 PVD33609.1 - 0.0054 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB MCLC PF05934.11 PVD33611.1 - 2.8 6.6 5.3 5 5.7 5.3 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) CBM_20 PF00686.19 PVD33612.1 - 2.2e-21 75.6 0.1 2.2e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 Starch binding domain Y_phosphatase PF00102.27 PVD33613.1 - 2.3e-73 246.6 0.0 3.3e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD33613.1 - 0.00038 20.3 0.1 0.001 18.9 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD33613.1 - 0.0031 17.5 0.0 0.0076 16.2 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family pEK499_p136 PF18736.1 PVD33613.1 - 0.016 14.8 0.2 0.031 13.9 0.2 1.4 1 0 0 1 1 1 0 HEPN pEK499 p136 Orthoreo_P10 PF07204.11 PVD33613.1 - 0.029 14.3 1.7 0.036 14.0 0.1 1.9 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 PAXNEB PF05625.11 PVD33614.1 - 1.1e-72 245.2 0.1 8.6e-40 137.0 0.0 2.0 1 1 1 2 2 2 2 PAXNEB protein ATPase PF06745.13 PVD33614.1 - 0.0054 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 KaiC F-box PF00646.33 PVD33615.1 - 0.041 13.8 0.2 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 PVD33615.1 - 0.1 12.9 0.3 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 PRANC domain EB PF01683.18 PVD33615.1 - 4.8 7.6 7.1 4.6 7.6 1.7 2.6 2 0 0 2 2 2 0 EB module Tetraspanin PF00335.20 PVD33616.1 - 7.6e-22 78.2 0.9 8.8e-22 77.9 0.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Baculo_11_kDa PF06143.11 PVD33616.1 - 7.7 6.2 6.8 17 5.1 6.8 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family COPIIcoated_ERV PF07970.12 PVD33617.1 - 4.7e-45 154.1 0.0 6.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PVD33617.1 - 4.7e-26 91.0 0.4 1.1e-25 89.7 0.4 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TMEM154 PF15102.6 PVD33618.1 - 0.00047 20.1 0.5 0.00047 20.1 0.5 2.5 3 0 0 3 3 3 1 TMEM154 protein family DUF5305 PF17231.2 PVD33618.1 - 0.0016 17.9 0.2 0.0044 16.4 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5305) DUF4328 PF14219.6 PVD33618.1 - 0.0034 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) EphA2_TM PF14575.6 PVD33618.1 - 0.023 15.5 0.7 0.12 13.2 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 PVD33618.1 - 0.031 14.3 0.2 0.069 13.2 0.0 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 PVD33618.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF5383 PF17355.2 PVD33618.1 - 0.086 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF3357 PF11837.8 PVD33618.1 - 0.097 13.1 0.1 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3377 PF11857.8 PVD33618.1 - 0.15 12.0 1.7 0.38 10.7 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) Acyl_CoA_thio PF02551.15 PVD33619.1 - 9.1e-05 22.3 1.0 1.7 8.5 0.0 3.3 3 0 0 3 3 3 2 Acyl-CoA thioesterase Neurexophilin PF06312.12 PVD33619.1 - 0.00015 21.3 0.3 3.9 6.9 0.0 3.3 3 0 0 3 3 3 3 Neurexophilin DUF3519 PF12033.8 PVD33619.1 - 0.34 11.3 1.9 3.1 8.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) DUF3054 PF11255.8 PVD33619.1 - 5.7 7.5 5.3 45 4.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) MAM PF00629.23 PVD33621.1 - 2.8e-08 33.8 0.1 4.7e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu TMEM154 PF15102.6 PVD33621.1 - 0.00079 19.4 1.1 0.0013 18.7 1.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF4711 PF15829.5 PVD33621.1 - 0.012 15.6 0.3 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DUF4328 PF14219.6 PVD33621.1 - 0.097 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DAG1 PF05454.11 PVD33621.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ephrin_lbd PF01404.19 PVD33621.1 - 0.11 12.5 5.8 1.3 9.1 1.0 2.3 1 1 1 2 2 2 0 Ephrin receptor ligand binding domain MAM PF00629.23 PVD33622.1 - 1.1e-08 35.2 6.4 7.8e-07 29.1 4.3 2.7 2 1 0 2 2 2 1 MAM domain, meprin/A5/mu TMEM154 PF15102.6 PVD33622.1 - 0.00011 22.1 0.9 0.0002 21.3 0.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family cEGF PF12662.7 PVD33622.1 - 0.02 14.8 1.7 0.069 13.1 1.7 2.0 1 0 0 1 1 1 0 Complement Clr-like EGF-like DUF5305 PF17231.2 PVD33622.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 PVD33622.1 - 0.043 14.7 0.0 0.15 12.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD33623.1 - 2.7e-06 27.4 1.0 7e-06 26.0 1.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family MAM PF00629.23 PVD33623.1 - 9.5e-06 25.6 0.1 1.9e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF5305 PF17231.2 PVD33623.1 - 0.0013 18.1 2.8 0.0031 16.9 1.3 2.1 1 1 2 3 3 3 1 Family of unknown function (DUF5305) DUF4328 PF14219.6 PVD33623.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF4711 PF15829.5 PVD33623.1 - 0.0062 16.5 0.2 0.0093 15.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) EphA2_TM PF14575.6 PVD33623.1 - 0.015 16.1 0.0 0.082 13.8 0.0 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 PVD33623.1 - 0.025 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5383 PF17355.2 PVD33623.1 - 0.12 12.8 0.3 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Sulfotransfer_2 PF03567.14 PVD33625.1 - 5.9e-11 42.8 0.2 0.0006 19.8 0.0 3.3 3 0 0 3 3 3 3 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD33626.1 - 1.1e-27 97.6 0.0 1.2e-23 84.4 0.0 2.7 2 0 0 2 2 2 2 Sulfotransferase family RabGAP-TBC PF00566.18 PVD33627.1 - 7.6e-12 45.3 0.4 2.8e-09 36.9 0.3 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain VPDSG-CTERM PF18205.1 PVD33627.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif Tetraspanin PF00335.20 PVD33628.1 - 7.6e-42 143.6 6.8 9.8e-42 143.2 6.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 PVD33628.1 - 0.041 13.9 1.5 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NOG1 PF06858.14 PVD33628.1 - 0.047 13.5 0.5 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) DUF3021 PF11457.8 PVD33628.1 - 0.2 12.0 9.0 0.13 12.6 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) MgtE PF01769.16 PVD33628.1 - 0.32 11.4 5.4 2.7 8.4 3.7 2.2 2 0 0 2 2 2 0 Divalent cation transporter DUF2981 PF11200.8 PVD33628.1 - 0.61 9.8 3.3 1 9.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4064 PF13273.6 PVD33628.1 - 0.73 10.1 0.1 0.73 10.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) eIF_4EBP PF05456.11 PVD33629.1 - 0.014 15.3 0.1 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) 7tm_1 PF00001.21 PVD33632.1 - 4.3e-17 62.3 1.9 6.3e-17 61.8 1.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD33632.1 - 3.7e-08 33.3 2.0 5.4e-08 32.8 2.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx HLH PF00010.26 PVD33632.1 - 2.1e-06 27.6 0.6 2.1e-06 27.6 0.6 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Serpentine_r_xa PF03383.15 PVD33632.1 - 0.017 15.1 1.6 0.027 14.4 1.6 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa WTF PF03303.13 PVD33632.1 - 0.075 12.7 0.4 0.099 12.4 0.4 1.3 1 0 0 1 1 1 0 WTF protein 7tm_1 PF00001.21 PVD33633.1 - 5.9e-10 38.9 9.4 4.4e-07 29.5 0.6 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD33633.1 - 0.00078 18.9 0.9 0.00078 18.9 0.9 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Reprolysin_5 PF13688.6 PVD33634.1 - 6.1e-18 65.7 1.4 8.4e-18 65.2 1.4 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD33634.1 - 4.2e-13 49.9 0.1 9.1e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD33634.1 - 2.1e-12 47.4 3.3 7.9e-11 42.2 0.1 2.2 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 PVD33634.1 - 9.3e-08 32.2 1.5 1.5e-07 31.5 1.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD33634.1 - 1.9e-06 27.7 10.6 1.2e-05 25.1 10.6 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 PVD33634.1 - 0.026 14.5 0.5 0.049 13.5 0.5 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 PVD33634.1 - 0.035 13.1 0.6 0.054 12.4 0.6 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 PVD33634.1 - 0.059 13.2 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin NADH5_C PF06455.11 PVD33634.1 - 0.067 12.8 1.3 0.073 12.7 0.1 1.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus 7tm_1 PF00001.21 PVD33635.1 - 0.0035 16.7 5.7 0.0043 16.4 5.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Voltage_CLC PF00654.20 PVD33635.1 - 0.19 10.9 6.6 0.21 10.8 6.6 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel 7tm_1 PF00001.21 PVD33636.1 - 0.0049 16.2 0.8 0.0072 15.7 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sulfatase PF00884.23 PVD33638.1 - 3.1e-38 131.9 1.5 5.7e-31 108.0 1.1 2.2 1 1 1 2 2 2 2 Sulfatase Sulfatase PF00884.23 PVD33639.1 - 6.6e-12 45.4 0.1 5.4e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 Sulfatase Sulfatase PF00884.23 PVD33640.1 - 7.8e-15 55.0 0.0 8.4e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Sulfatase HXXEE PF13787.6 PVD33640.1 - 0.098 13.5 0.1 0.12 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif eIF3m_C_helix PF18005.1 PVD33641.1 - 0.13 11.9 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Trypsin PF00089.26 PVD33642.1 - 1.6e-31 109.8 2.8 7.2e-28 97.9 2.8 2.2 1 1 0 1 1 1 1 Trypsin Sulfatase PF00884.23 PVD33642.1 - 3.5e-25 89.0 12.0 1.5e-22 80.4 3.1 4.4 2 2 2 4 4 4 3 Sulfatase Sulfatase_C PF14707.6 PVD33642.1 - 0.0012 19.5 0.0 0.0025 18.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD33642.1 - 0.002 18.0 0.2 0.078 12.9 0.1 3.2 3 1 0 3 3 3 1 Domain of unknown function Trypsin_2 PF13365.6 PVD33642.1 - 0.13 13.2 0.8 3.8 8.4 0.8 2.2 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 PVD33643.1 - 1.5e-61 208.1 11.3 1.3e-34 119.9 0.9 3.2 2 1 1 3 3 3 3 Trypsin Sulfatase PF00884.23 PVD33643.1 - 5.3e-16 58.9 0.1 2.3e-05 24.0 0.0 3.3 2 1 1 3 3 3 3 Sulfatase Trypsin_2 PF13365.6 PVD33643.1 - 1.9e-05 25.6 0.3 0.0026 18.7 0.2 2.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF4994 PF16385.5 PVD33643.1 - 3.4e-05 23.7 0.3 0.00041 20.2 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 PVD33643.1 - 0.00014 22.6 0.0 0.00033 21.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD33643.1 - 0.0082 16.4 0.1 0.54 10.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) MFA1_2 PF17317.2 PVD33643.1 - 0.016 14.9 0.1 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 DUF898 PF05987.13 PVD33643.1 - 0.77 8.7 7.7 1.1 8.3 7.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) KxDL PF10241.9 PVD33645.1 - 0.02 15.2 0.1 0.057 13.7 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Macoilin PF09726.9 PVD33645.1 - 2.4 6.6 5.5 2.9 6.3 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Mastoparan_2 PF08251.11 PVD33648.1 - 1.3e-07 31.1 5.9 3.4e+02 2.0 0.0 11.7 14 0 0 14 14 14 0 Mastoparan peptide zf-H2C2_2 PF13465.6 PVD33649.1 - 3e-31 106.4 47.9 2.5e-07 30.8 0.6 7.5 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 PVD33649.1 - 3.2e-28 96.6 46.1 2.3e-05 24.6 0.2 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33649.1 - 9.4e-16 57.2 43.6 0.012 16.3 0.2 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD33649.1 - 1.3e-06 28.6 14.6 0.018 15.3 7.4 3.7 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 PVD33649.1 - 0.00055 20.1 21.8 0.51 10.4 0.4 5.4 2 2 2 4 4 4 3 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 PVD33649.1 - 0.0012 19.1 9.9 0.29 11.5 0.2 5.4 6 0 0 6 6 6 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 PVD33649.1 - 0.0085 16.8 1.0 0.0085 16.8 1.0 3.7 2 2 2 4 4 4 1 TRAF-type zinc finger SBP PF03110.14 PVD33649.1 - 3.5 8.0 6.7 37 4.7 0.1 2.9 2 0 0 2 2 2 0 SBP domain FOXP-CC PF16159.5 PVD33649.1 - 3.8 8.2 8.7 69 4.2 0.1 5.0 4 1 1 5 5 5 0 FOXP coiled-coil domain Collagen PF01391.18 PVD33650.1 - 0.84 9.4 7.7 23 4.8 7.7 2.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) CUT PF02376.15 PVD33651.1 - 0.044 13.9 0.1 0.054 13.7 0.1 1.1 1 0 0 1 1 1 0 CUT domain Reprolysin_5 PF13688.6 PVD33653.1 - 8.3e-09 35.9 0.4 1e-08 35.6 0.4 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD33653.1 - 4.4e-06 26.7 0.6 7e-06 26.1 0.6 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD33653.1 - 1.5e-05 25.5 0.1 2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD33653.1 - 1.7e-05 24.6 0.1 1.9e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD33653.1 - 0.00029 20.8 0.0 0.00037 20.5 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 PVD33653.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Matrixin zf-C4 PF00105.18 PVD33654.1 - 8e-26 90.3 9.2 8e-26 90.3 9.2 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD33654.1 - 8e-07 28.8 0.0 2.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD33655.1 - 9e-27 93.3 10.6 2.1e-26 92.1 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD33655.1 - 1.6e-15 57.3 0.7 1.4e-14 54.2 0.7 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 PVD33655.1 - 0.036 14.2 3.3 0.11 12.7 3.3 1.8 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DJ-1_PfpI PF01965.24 PVD33656.1 - 0.00025 20.9 0.0 0.00079 19.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 PVD33656.1 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like Bac_surface_Ag PF01103.23 PVD33657.1 - 9.3e-40 137.1 0.1 1.1e-39 136.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 PVD33657.1 - 0.058 14.0 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat POTRA_1 PF08478.10 PVD33657.1 - 0.086 13.2 0.3 0.25 11.7 0.2 1.8 2 0 0 2 2 2 0 POTRA domain, FtsQ-type SPT2 PF08243.11 PVD33658.1 - 3e-21 76.0 20.8 3e-21 76.0 20.8 6.9 6 2 1 7 7 7 1 SPT2 chromatin protein Bromodomain PF00439.25 PVD33659.1 - 9.2e-26 89.7 0.5 3e-25 88.1 0.5 2.0 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 PVD33659.1 - 2.3e-20 72.2 26.0 3.2e-11 43.0 9.4 2.6 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 PVD33659.1 - 2e-18 66.7 0.0 2e-18 66.7 0.0 4.4 5 0 0 5 5 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 PVD33659.1 - 5.3e-07 29.0 0.5 1.3e-06 27.8 0.5 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 PVD33659.1 - 0.00032 20.2 11.8 0.011 15.3 1.0 2.8 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.6 PVD33659.1 - 0.0054 17.0 9.1 0.0054 17.0 9.1 2.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 PVD33659.1 - 0.0054 16.6 16.7 0.11 12.5 4.5 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 PVD33659.1 - 0.017 15.3 18.8 0.28 11.4 8.5 3.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 PVD33659.1 - 0.063 13.2 20.8 0.17 11.8 4.7 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acyl-ACP_TE PF01643.17 PVD33659.1 - 0.61 9.3 7.6 0.029 13.7 1.4 1.9 2 0 0 2 2 2 0 Acyl-ACP thioesterase zinc_ribbon_4 PF13717.6 PVD33659.1 - 1.6 8.7 9.3 0.18 11.8 1.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-HC5HC2H_2 PF13832.6 PVD33659.1 - 2.6 8.2 16.6 9.9 6.4 5.8 2.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-rbx1 PF12678.7 PVD33659.1 - 3.5 8.0 20.9 4.7 7.6 8.7 3.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain XPG_I PF00867.18 PVD33660.1 - 3.8e-16 59.2 0.0 1.2e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PVD33660.1 - 2.7e-15 56.7 0.1 5.9e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Chromo_2 PF18704.1 PVD33660.1 - 0.00022 21.4 0.0 0.00068 19.9 0.0 1.9 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 EMP24_GP25L PF01105.24 PVD33661.1 - 3e-33 115.3 4.0 7.6e-33 114.0 4.0 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bromodomain PF00439.25 PVD33662.1 - 1e-15 57.6 0.4 2e-15 56.6 0.4 1.5 1 0 0 1 1 1 1 Bromodomain WHIM1 PF15612.6 PVD33662.1 - 0.0005 19.5 0.4 0.0017 17.8 0.4 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2390 PF09523.10 PVD33662.1 - 1.7 9.0 5.9 2.8 8.3 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) RIC3 PF15361.6 PVD33664.1 - 7.5e-22 78.3 0.7 1.7e-21 77.1 0.7 1.6 1 1 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF892 PF05974.12 PVD33664.1 - 0.02 14.9 1.4 0.036 14.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) CNOT11 PF10155.9 PVD33665.1 - 1.5e-54 183.5 7.0 1.5e-54 183.5 7.0 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 DXP_redisom_C PF08436.12 PVD33665.1 - 0.009 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Creb_binding PF09030.10 PVD33665.1 - 0.02 15.6 1.3 0.042 14.6 0.0 2.2 3 0 0 3 3 3 0 Creb binding Y_phosphatase PF00102.27 PVD33666.1 - 1.9e-18 66.9 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 PVD33666.1 - 1.6e-12 47.6 0.2 3e-05 24.3 0.0 5.1 4 1 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD33666.1 - 0.036 14.6 0.0 20 5.8 0.0 4.7 4 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 PVD33666.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD33667.1 - 1.7e-18 67.0 1.2 2.2e-18 66.7 1.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD33667.1 - 3.5e-05 23.6 0.1 5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 PVD33667.1 - 0.00027 20.0 0.1 0.00036 19.6 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 PVD33667.1 - 0.0024 18.0 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PVD33667.1 - 0.0083 16.1 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family NUP50 PF08911.11 PVD33668.1 - 2.1e-16 60.4 3.4 1.1e-15 58.1 0.1 2.7 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 PVD33668.1 - 3e-09 37.2 0.0 5.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain PHD PF00628.29 PVD33669.1 - 2.2e-09 37.1 2.4 3.8e-09 36.3 2.4 1.4 1 0 0 1 1 1 1 PHD-finger CENP-H PF05837.12 PVD33669.1 - 0.0048 17.3 17.4 0.029 14.8 1.3 2.5 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Atg14 PF10186.9 PVD33669.1 - 0.017 14.2 0.5 0.017 14.2 0.5 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 PHD_2 PF13831.6 PVD33669.1 - 0.045 13.3 0.4 0.1 12.2 0.4 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 PVD33669.1 - 0.046 13.6 1.4 0.094 12.6 1.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VIT1 PF01988.19 PVD33669.1 - 0.21 11.4 6.1 0.18 11.7 0.8 2.2 2 0 0 2 2 2 0 VIT family Spc24 PF08286.11 PVD33669.1 - 0.37 11.0 15.0 0.79 10.0 0.5 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-rbx1 PF12678.7 PVD33669.1 - 0.88 9.9 2.8 1.9 8.8 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain HAUS-augmin3 PF14932.6 PVD33669.1 - 0.94 9.0 18.2 1 8.9 9.3 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 zf-PHD-like PF15446.6 PVD33669.1 - 1.4 8.6 7.2 0.16 11.6 0.8 2.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 PVD33669.1 - 2.7 8.2 5.6 11 6.2 5.6 2.1 1 1 0 1 1 1 0 PHD-finger Cas9_PI PF16595.5 PVD33669.1 - 2.9 7.7 10.8 0.22 11.4 3.7 2.0 2 0 0 2 2 2 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 APG6_N PF17675.1 PVD33669.1 - 7.4 7.1 26.1 1.8 9.1 8.8 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region MFS_1 PF07690.16 PVD33670.1 - 1.1e-12 47.6 36.8 1.6e-09 37.1 9.7 3.4 2 2 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD33670.1 - 1.4e-09 37.0 30.4 1.9e-09 36.6 6.1 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein RAD51_interact PF15696.5 PVD33671.1 - 5e-12 45.7 4.3 1.7e-11 44.0 4.3 2.0 1 0 0 1 1 1 1 RAD51 interacting motif C1q PF00386.21 PVD33672.1 - 8.4e-20 71.3 0.0 1.4e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD33672.1 - 0.00033 20.6 0.2 0.00053 19.9 0.2 1.3 1 0 0 1 1 1 1 BclA C-terminal domain PPC PF04151.15 PVD33672.1 - 0.089 13.9 0.5 0.37 11.9 0.2 2.1 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain C1q PF00386.21 PVD33673.1 - 2.6e-23 82.6 0.1 3.2e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD33673.1 - 2.1e-06 27.6 0.2 2.8e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 BclA C-terminal domain TNF PF00229.18 PVD33673.1 - 0.005 16.8 0.0 0.023 14.7 0.0 2.1 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family PA14 PF07691.12 PVD33673.1 - 0.019 14.8 0.2 0.9 9.3 0.0 2.3 1 1 1 2 2 2 0 PA14 domain PPC PF04151.15 PVD33673.1 - 0.02 16.0 0.8 0.078 14.1 0.1 2.1 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Cupin_8 PF13621.6 PVD33674.1 - 1.9e-36 126.1 0.0 2.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain C1q PF00386.21 PVD33674.1 - 1.2e-20 74.0 0.0 2.3e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD33674.1 - 0.00023 21.1 0.1 0.00042 20.2 0.1 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Cupin_4 PF08007.12 PVD33674.1 - 0.049 13.1 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein PPC PF04151.15 PVD33674.1 - 0.17 13.0 0.5 0.78 10.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain ubiquitin PF00240.23 PVD33675.1 - 0.037 13.8 4.1 1.4 8.8 0.2 2.5 1 1 1 2 2 2 0 Ubiquitin family ig PF00047.25 PVD33676.1 - 2.1e-06 27.8 0.0 2.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD33676.1 - 3e-05 24.5 0.1 3.8e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD33676.1 - 0.012 15.8 0.1 0.097 12.9 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain COMM_domain PF07258.14 PVD33678.1 - 2.5e-22 78.8 0.2 3.2e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 COMM domain DUF4611 PF15387.6 PVD33678.1 - 0.011 15.9 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SEFIR PF08357.11 PVD33679.1 - 3.2e-17 63.2 0.5 5e-17 62.6 0.5 1.3 1 0 0 1 1 1 1 SEFIR domain Death PF00531.22 PVD33679.1 - 5.8e-09 36.0 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Death domain TIR_2 PF13676.6 PVD33679.1 - 6.1e-07 30.1 0.1 1.6e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 TIR domain BCDHK_Adom3 PF10436.9 PVD33680.1 - 0.044 13.6 0.1 0.42 10.4 0.2 2.5 2 1 1 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase 7tm_1 PF00001.21 PVD33681.1 - 9.3e-11 41.5 3.0 5.5e-08 32.5 1.5 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD33681.1 - 8.9e-07 28.5 14.3 0.00014 21.3 9.4 2.6 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD33681.1 - 0.0079 15.6 9.9 0.033 13.6 2.7 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3098 PF11297.8 PVD33681.1 - 0.037 13.6 2.2 0.18 11.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Corona_7 PF02398.16 PVD33681.1 - 0.1 13.2 5.4 1.3 9.6 0.0 3.1 2 1 1 3 3 3 0 Coronavirus protein 7 DUF3810 PF12725.7 PVD33681.1 - 4.7 6.5 7.8 7 5.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) NAM-associated PF14303.6 PVD33682.1 - 0.00034 21.4 8.2 0.00034 21.4 8.2 1.8 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain RAP1 PF07218.11 PVD33682.1 - 0.042 12.2 2.0 0.061 11.6 2.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 PVD33682.1 - 3.4 7.2 15.2 0.17 11.5 8.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YbgS PF13985.6 PVD33683.1 - 1.4 9.2 7.0 4.4 7.6 2.0 2.8 3 0 0 3 3 3 0 YbgS-like protein Arm PF00514.23 PVD33684.1 - 1.5e-18 66.1 0.1 2.1e-05 24.4 0.0 6.2 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PVD33684.1 - 1.5e-11 43.5 0.5 0.0013 18.9 0.1 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 PVD33684.1 - 4.1e-08 33.5 0.6 4.1e-05 23.9 0.2 3.3 2 2 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 PVD33684.1 - 4.4e-08 33.3 0.2 0.00087 19.4 0.1 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PVD33684.1 - 6.7e-07 29.7 3.7 0.0042 17.6 0.2 4.6 5 1 1 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.20 PVD33684.1 - 1.4e-05 23.9 0.1 2.2e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 PVD33684.1 - 0.0011 19.6 0.0 0.14 12.8 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PVD33684.1 - 0.0043 16.6 0.5 3 7.3 0.0 3.6 1 1 3 4 4 4 1 CLASP N terminal MMS19_N PF14500.6 PVD33684.1 - 0.12 11.9 0.2 6.5 6.3 0.1 2.6 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II 3-PAP PF12578.8 PVD33685.1 - 0.2 11.4 0.6 0.26 11.0 0.6 1.2 1 0 0 1 1 1 0 Myotubularin-associated protein Pil1 PF13805.6 PVD33686.1 - 9.7e-11 41.7 10.5 1.4e-10 41.1 10.5 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 TMF_TATA_bd PF12325.8 PVD33686.1 - 3.9 7.7 14.0 4 7.7 5.2 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Peptidase_M13_N PF05649.13 PVD33687.1 - 1.5e-74 252.0 3.2 2.3e-74 251.4 3.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD33687.1 - 6.1e-27 94.6 0.5 1.9e-26 93.0 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M13 LIM PF00412.22 PVD33688.1 - 1.9e-09 37.6 11.4 3.2e-09 36.9 11.4 1.4 1 0 0 1 1 1 1 LIM domain Myb_DNA-bind_7 PF15963.5 PVD33690.1 - 2e-28 98.1 5.1 2e-28 98.1 5.1 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 PVD33690.1 - 2.1e-05 24.6 0.2 5.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_1 PF00515.28 PVD33691.1 - 6.7e-07 28.9 8.3 0.016 15.0 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33691.1 - 0.00082 19.3 9.3 0.056 13.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SHOCT PF09851.9 PVD33691.1 - 0.26 11.1 2.3 0.32 10.8 0.7 2.0 2 0 0 2 2 2 0 Short C-terminal domain TPR_8 PF13181.6 PVD33691.1 - 1.2 9.6 7.4 16 6.0 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD33691.1 - 3.7 8.1 4.8 88 3.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PurA PF04845.13 PVD33692.1 - 6.6e-101 336.2 0.1 8e-101 335.9 0.1 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 PVD33692.1 - 3.1e-05 24.1 0.1 1.7 8.8 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) EFG_C PF00679.24 PVD33692.1 - 0.00066 19.7 0.0 5.3 7.1 0.0 3.2 3 0 0 3 3 3 2 Elongation factor G C-terminus Herpes_US12 PF05363.12 PVD33692.1 - 0.086 13.6 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus US12 family RRM_1 PF00076.22 PVD33693.1 - 8.2e-29 99.2 1.3 8.7e-15 54.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD33693.1 - 7.9e-09 35.2 0.0 0.00021 20.9 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD33693.1 - 6.9e-08 32.2 0.1 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 PVD33693.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 PVD33693.1 - 0.042 14.1 1.1 8.4 6.6 0.1 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter UDPGP PF01704.18 PVD33694.1 - 2.8e-69 233.8 0.0 3.4e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 PVD33694.1 - 0.0065 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain PI3_PI4_kinase PF00454.27 PVD33696.1 - 2.7e-52 178.1 0.8 2.9e-51 174.7 0.8 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PVD33696.1 - 1.4e-38 132.1 0.4 1.4e-38 132.1 0.4 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 PVD33696.1 - 4.9e-19 68.5 0.1 2.5e-18 66.3 0.1 2.3 2 0 0 2 2 2 1 C2 domain PI3K_rbd PF00794.18 PVD33696.1 - 7.6e-19 67.9 0.3 2.3e-18 66.3 0.3 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 PVD33696.1 - 1.5e-14 54.1 0.0 1.2e-12 48.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PX PF00787.24 PVD33696.1 - 1.3e-11 44.5 1.2 4.1e-11 42.9 1.2 2.0 1 0 0 1 1 1 1 PX domain DUF4135 PF13575.6 PVD33696.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Peptidase_M13_N PF05649.13 PVD33697.1 - 7.8e-25 88.4 0.6 9.3e-25 88.1 0.6 1.0 1 0 0 1 1 1 1 Peptidase family M13 DUF829 PF05705.14 PVD33697.1 - 0.049 13.5 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF1043 PF06295.12 PVD33697.1 - 0.07 13.1 0.2 0.093 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Peptidase_M13_N PF05649.13 PVD33698.1 - 1.3e-44 153.4 0.2 1.7e-44 153.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD33698.1 - 9.8e-22 77.6 1.0 6.4e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 Peptidase family M13 Frag1 PF10277.9 PVD33699.1 - 4.3e-40 137.6 7.8 5.4e-40 137.3 7.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4190 PF13828.6 PVD33699.1 - 0.06 13.1 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2721 PF11026.8 PVD33699.1 - 0.19 11.6 5.8 1.4 8.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) DUF4131 PF13567.6 PVD33699.1 - 6.1 6.5 9.4 5.1 6.7 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DAP_epimerase PF01678.19 PVD33702.1 - 1.2e-27 96.5 0.4 5.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Diaminopimelate epimerase Ank_4 PF13637.6 PVD33704.1 - 8.1e-10 39.0 0.1 2.4e-05 24.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33704.1 - 1.1e-09 38.7 0.3 7.2e-06 26.5 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33704.1 - 1.1e-08 34.7 0.2 0.069 13.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD33704.1 - 0.0001 22.6 0.1 0.16 12.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD33704.1 - 0.00017 21.8 0.1 0.057 13.8 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 PVD33704.1 - 0.0065 16.4 0.8 0.4 10.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) PDGF_N PF04692.13 PVD33704.1 - 0.46 11.3 5.0 0.68 10.8 3.9 1.9 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region SelP_N PF04592.14 PVD33704.1 - 0.69 9.3 13.4 1.2 8.5 13.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ion_trans PF00520.31 PVD33707.1 - 4e-07 29.5 0.9 4e-07 29.5 0.9 1.0 1 0 0 1 1 1 1 Ion transport protein DUF5391 PF17369.2 PVD33707.1 - 0.32 11.0 4.3 0.054 13.5 0.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5391) Ion_trans PF00520.31 PVD33708.1 - 1.1e-06 28.1 0.5 1.4e-06 27.8 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PVD33708.1 - 0.097 11.3 0.3 0.13 10.9 0.3 1.1 1 0 0 1 1 1 0 Polycystin cation channel Bcl-2 PF00452.19 PVD33709.1 - 3.4e-22 79.0 0.0 6.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family PAX PF00292.18 PVD33709.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain MCM PF00493.23 PVD33712.1 - 3.3e-77 258.6 0.0 6.3e-77 257.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PVD33712.1 - 5.6e-23 81.2 3.5 1.6e-22 79.7 3.5 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PVD33712.1 - 7.3e-14 52.0 7.3 7.7e-14 51.9 5.3 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_5 PF07728.14 PVD33712.1 - 7.8e-09 35.6 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PVD33712.1 - 4.4e-08 32.8 0.0 0.00029 20.3 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PVD33712.1 - 0.013 15.2 0.0 0.26 11.0 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 PVD33712.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RII_binding_1 PF10522.9 PVD33712.1 - 0.063 13.5 1.6 0.22 11.8 1.6 1.9 1 0 0 1 1 1 0 RII binding domain AAA_16 PF13191.6 PVD33712.1 - 0.072 13.5 0.8 0.89 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Topoisom_bac PF01131.20 PVD33713.1 - 1.1e-112 377.0 0.0 1.5e-112 376.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PVD33713.1 - 2.7e-17 62.9 0.0 6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain FoP_duplication PF13865.6 PVD33713.1 - 5.8 7.5 10.0 11 6.6 10.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CH PF00307.31 PVD33715.1 - 6.3e-15 55.3 0.1 8.8e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD33715.1 - 0.002 17.9 0.1 0.0033 17.2 0.1 1.4 1 1 0 1 1 1 1 CAMSAP CH domain Tmemb_55A PF09788.9 PVD33715.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Mis14 PF08641.12 PVD33716.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Kinetochore protein Mis14 like cNMP_binding PF00027.29 PVD33717.1 - 6.5e-19 67.8 0.1 0.0016 18.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 PVD33717.1 - 0.063 13.0 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain LPD39 PF18858.1 PVD33717.1 - 2.2 8.3 6.0 2.7 8.0 0.2 2.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 BORA_N PF15280.6 PVD33718.1 - 8.9e-33 113.9 3.9 2.5e-28 99.3 0.2 2.8 1 1 0 2 2 2 2 Protein aurora borealis N-terminus 5HT_transport_N PF03491.13 PVD33719.1 - 3.5e-06 27.1 12.9 3.2 8.0 0.2 5.8 6 0 0 6 6 6 4 Serotonin (5-HT) neurotransmitter transporter, N-terminus T2SSB PF16537.5 PVD33719.1 - 0.00035 20.1 1.6 25 4.6 0.0 4.3 4 0 0 4 4 4 2 Type II secretion system protein B MoaF_C PF17409.2 PVD33719.1 - 0.0014 18.2 0.0 48 3.7 0.0 4.0 4 0 0 4 4 4 0 MoaF C-terminal domain Glyphos_transf PF04464.14 PVD33719.1 - 0.009 15.0 0.0 21 3.9 0.0 3.7 4 0 0 4 4 4 2 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NAAA-beta PF15508.6 PVD33719.1 - 0.012 15.9 0.0 61 4.0 0.0 4.1 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase XTBD PF11952.8 PVD33719.1 - 0.027 14.2 0.0 20 5.0 0.0 3.8 4 0 0 4 4 4 0 XRN-Two Binding Domain, XTBD Rab3-GTPase_cat PF13890.6 PVD33719.1 - 0.14 11.8 0.0 32 4.1 0.0 3.3 4 0 0 4 4 4 0 Rab3 GTPase-activating protein catalytic subunit Exo_endo_phos PF03372.23 PVD33720.1 - 2.4e-09 37.1 0.3 4.3e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD33720.1 - 3.3e-08 33.4 0.0 7.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD33720.1 - 0.0038 16.8 0.1 0.0074 15.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_15 PF13175.6 PVD33720.1 - 0.27 10.9 6.8 0.57 9.8 6.8 1.5 1 1 0 1 1 1 0 AAA ATPase domain Pex16 PF08610.10 PVD33721.1 - 7e-74 248.9 0.1 9.2e-74 248.5 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Glyco_transf_49 PF13896.6 PVD33722.1 - 3.2e-61 207.5 2.6 2.3e-49 168.5 1.5 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 PVD33722.1 - 2.5e-17 63.3 0.6 4.4e-17 62.5 0.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 PVD33722.1 - 0.0095 15.4 2.3 0.017 14.5 1.3 1.8 1 1 1 2 2 2 1 Glucosyltransferase 24 Nucleotid_trans PF03407.16 PVD33722.1 - 0.028 14.4 0.4 0.59 10.1 0.2 2.5 2 1 0 2 2 2 0 Nucleotide-diphospho-sugar transferase ANAPC4_WD40 PF12894.7 PVD33723.1 - 6.4e-05 23.2 0.1 0.00022 21.5 0.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 PVD33723.1 - 0.0078 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 CPSF A subunit region ANF_receptor PF01094.28 PVD33724.1 - 8e-24 84.4 0.1 1.1e-23 84.0 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD33725.1 - 4.3e-55 187.0 11.9 6.1e-55 186.5 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD33725.1 - 8.2e-10 38.3 0.1 1.2e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD33725.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF2254 PF10011.9 PVD33725.1 - 0.8 8.5 5.2 1.6 7.4 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF2975 PF11188.8 PVD33725.1 - 1.2 9.0 15.7 1.2 9.1 2.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2975) Cation_ATPase_C PF00689.21 PVD33725.1 - 2.8 7.6 13.9 4.6 6.9 0.4 2.9 1 1 1 3 3 3 0 Cation transporting ATPase, C-terminus ATP-synt_8 PF00895.20 PVD33725.1 - 3 8.4 5.0 2.1 8.9 0.1 2.9 3 0 0 3 3 3 0 ATP synthase protein 8 CD225 PF04505.12 PVD33726.1 - 1.7e-16 60.1 0.7 2.4e-16 59.6 0.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ABC2_membrane PF01061.24 PVD33726.1 - 0.00044 19.7 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF2852 PF11014.8 PVD33726.1 - 0.1 12.8 0.4 0.23 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF4190 PF13828.6 PVD33726.1 - 0.17 11.7 5.9 0.68 9.7 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) DUF2207 PF09972.9 PVD33726.1 - 0.26 10.0 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spt5-NGN PF03439.13 PVD33727.1 - 5.7e-26 90.2 0.4 1.1e-25 89.3 0.4 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 PVD33727.1 - 2e-24 84.7 21.6 1.8e-07 30.9 0.8 6.8 7 0 0 7 7 7 5 KOW motif Spt5_N PF11942.8 PVD33727.1 - 1.3e-12 48.5 11.4 1.3e-12 48.5 11.4 3.2 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 PVD33727.1 - 0.00016 21.9 2.4 0.0021 18.3 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3912) DUF150_C PF17384.2 PVD33727.1 - 0.0044 17.1 3.0 0.37 11.0 0.0 3.9 4 0 0 4 4 4 1 RimP C-terminal SH3 domain NAM-associated PF14303.6 PVD33727.1 - 8.2 7.1 6.5 19 5.9 6.5 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ELO PF01151.18 PVD33728.1 - 9.1e-63 212.1 25.8 1.3e-62 211.6 25.8 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family zf_CCCH_4 PF18345.1 PVD33728.1 - 3.4e-05 23.7 4.9 6.6e-05 22.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PVD33728.1 - 5.2e-05 23.0 3.3 9.4e-05 22.2 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DnaI_N PF07319.11 PVD33728.1 - 0.0017 19.0 1.6 0.0068 17.1 0.0 3.0 3 0 0 3 3 3 1 Primosomal protein DnaI N-terminus zf-CCCH_4 PF18044.1 PVD33728.1 - 0.0038 17.0 2.1 0.0069 16.2 2.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 PVD33728.1 - 0.011 16.4 0.1 0.011 16.4 0.1 2.7 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 PVD33728.1 - 0.11 13.0 4.7 0.22 12.1 4.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SNF2_N PF00176.23 PVD33729.1 - 4.9e-56 189.9 0.5 1.4e-55 188.5 0.5 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD33729.1 - 4.6e-18 65.6 0.5 3.1e-17 62.9 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD33729.1 - 1.5e-11 44.6 0.1 1.1e-09 38.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD33729.1 - 2.9e-06 27.2 0.0 9.6e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 PVD33729.1 - 5.5e-06 25.8 0.0 5.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase LIG3_BRCT PF16759.5 PVD33729.1 - 0.0096 16.2 0.0 0.042 14.1 0.0 2.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain RuvB_N PF05496.12 PVD33729.1 - 0.16 11.7 0.4 1.1 9.0 0.0 2.6 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain Vps54_N PF10475.9 PVD33730.1 - 7.7e-99 330.6 6.0 7.7e-99 330.6 6.0 2.2 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 PVD33730.1 - 3.1e-42 145.0 10.9 3.4e-24 85.9 0.1 4.1 3 1 1 4 4 4 2 Protein of unknown function C-terminus (DUF2451) YL1 PF05764.13 PVD33730.1 - 0.045 13.9 7.5 0.092 12.9 7.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein TMEM154 PF15102.6 PVD33731.1 - 0.0059 16.5 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family DUF3827 PF12877.7 PVD33731.1 - 2.5 6.4 6.8 0.2 10.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Cnd1 PF12717.7 PVD33732.1 - 1.5e-29 103.1 10.5 2.2e-21 76.6 0.0 5.9 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PVD33732.1 - 4.4e-09 35.8 10.1 1.6 9.2 0.1 7.3 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.7 PVD33732.1 - 9.2e-05 22.7 5.0 0.7 10.3 0.2 4.1 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 PVD33732.1 - 0.00061 20.1 5.7 0.48 10.8 0.1 5.0 5 1 0 5 5 5 2 HEAT repeats ddrB-ParB PF18763.1 PVD33732.1 - 1.1 9.3 4.9 1.2 9.3 0.7 2.5 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain OSCP PF00213.18 PVD33732.1 - 2.6 8.2 8.8 1 9.4 1.4 3.0 3 1 0 4 4 4 0 ATP synthase delta (OSCP) subunit Cu-oxidase_2 PF07731.14 PVD33733.1 - 2.3e-31 108.4 1.6 1.3e-30 106.0 0.5 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 PVD33733.1 - 3.6e-22 79.2 0.0 1.5e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 PVD33733.1 - 2.1e-08 34.2 5.5 1.2e-06 28.6 0.3 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 PVD33733.1 - 0.13 12.4 0.0 5.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Cupredoxin-like domain Peptidase_M14 PF00246.24 PVD33734.1 - 1.7e-18 67.5 0.0 4.9e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 PVD33734.1 - 2.1e-15 57.0 1.3 2.1e-15 57.0 1.3 1.9 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain DUF3731 PF12531.8 PVD33734.1 - 0.11 12.3 0.5 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 DNA-K related protein Asp23 PF03780.13 PVD33734.1 - 0.13 12.7 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function ADH_zinc_N PF00107.26 PVD33735.1 - 3e-24 85.4 0.0 5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD33735.1 - 2.5e-12 48.0 0.0 5.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD33735.1 - 3.6e-10 39.7 0.1 2.2e-08 33.9 0.0 3.2 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PVD33735.1 - 0.0025 17.7 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase SH3_3 PF08239.11 PVD33735.1 - 0.063 13.6 0.0 1.8 8.9 0.0 2.5 1 1 1 2 2 2 0 Bacterial SH3 domain SET PF00856.28 PVD33736.1 - 9.6e-13 48.9 0.3 2.8e-12 47.4 0.3 2.0 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 PVD33736.1 - 5.3e-09 35.5 8.8 7.8e-05 22.3 0.4 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33736.1 - 1.5e-07 31.0 7.9 0.00083 19.3 0.6 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33736.1 - 5.4e-05 23.1 2.4 0.13 12.5 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD33736.1 - 0.00012 22.2 0.2 0.52 10.6 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD33736.1 - 0.00056 19.7 0.1 0.03 14.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD33736.1 - 0.012 15.8 2.6 0.078 13.2 2.5 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PVD33736.1 - 0.025 14.3 0.4 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 TPR repeat DUF3856 PF12968.7 PVD33736.1 - 0.15 12.1 0.8 0.77 9.8 0.8 2.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) NOB1_Zn_bind PF08772.11 PVD33736.1 - 3.9 7.7 6.5 0.4 10.9 1.0 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Peptidase_M28 PF04389.17 PVD33737.1 - 2.8e-27 95.7 0.0 4.5e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD33737.1 - 4e-12 46.0 0.0 8.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 PVD33737.1 - 0.00025 20.6 0.0 0.00057 19.4 0.0 1.5 1 0 0 1 1 1 1 Nicastrin TFR_dimer PF04253.15 PVD33737.1 - 0.0006 19.9 0.1 0.0013 18.8 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M20 PF01546.28 PVD33737.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RRM_1 PF00076.22 PVD33738.1 - 1.1e-18 66.8 0.0 1.5e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD33738.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 PVD33738.1 - 0.0014 18.6 5.0 0.0032 17.4 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PVD33738.1 - 0.0017 18.4 7.2 0.0037 17.3 7.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 PVD33738.1 - 0.0062 16.2 2.1 0.014 15.1 2.1 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 PVD33738.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 PVD33738.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RSRP PF17069.5 PVD33738.1 - 4.9 6.6 44.8 0.63 9.6 40.3 1.8 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 RRM_1 PF00076.22 PVD33739.1 - 1.9e-07 30.8 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PVD33739.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain Lig_chan PF00060.26 PVD33740.1 - 1.5e-32 112.5 0.5 2.4e-32 111.8 0.5 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD33740.1 - 5.4e-17 62.0 0.4 2.9e-13 49.8 0.1 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 PVD33740.1 - 1.6e-13 50.9 0.1 5.1e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site TMEM154 PF15102.6 PVD33740.1 - 0.046 13.6 0.4 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family OAD_gamma PF04277.13 PVD33740.1 - 0.22 12.1 0.1 0.22 12.1 0.1 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ANF_receptor PF01094.28 PVD33741.1 - 0.0097 15.0 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2195 PF09961.9 PVD33742.1 - 0.066 13.2 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) Lig_chan-Glu_bd PF10613.9 PVD33743.1 - 3.4e-31 107.8 0.0 6.6e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD33743.1 - 5.1e-29 101.0 0.6 1e-28 100.0 0.6 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD33743.1 - 4.7e-21 75.3 0.0 1e-20 74.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans PF00520.31 PVD33744.1 - 4.5e-40 137.4 10.9 5.9e-40 137.0 10.9 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD33744.1 - 8.6e-31 106.1 0.0 1.6e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD33744.1 - 1.7e-10 40.7 8.0 3.2e-10 39.8 4.8 2.4 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 PVD33744.1 - 0.00076 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 PVD33744.1 - 0.48 9.0 8.7 0.031 13.0 2.9 1.8 1 1 1 2 2 2 0 Polycystin cation channel G_glu_transpept PF01019.21 PVD33745.1 - 2.9e-136 455.2 0.0 2.9e-136 455.2 0.0 1.6 2 0 0 2 2 2 1 Gamma-glutamyltranspeptidase BCL9 PF11502.8 PVD33748.1 - 7.8e-12 44.8 1.1 7.8e-12 44.8 1.1 3.1 2 0 0 2 2 2 1 B-cell lymphoma 9 protein Atg8 PF02991.16 PVD33750.1 - 6.3e-36 122.7 0.9 4.9e-35 119.8 0.9 2.2 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like Gly_transf_sug PF04488.15 PVD33750.1 - 5.2e-09 36.6 0.0 2.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif APG12 PF04110.13 PVD33750.1 - 0.0011 19.3 0.1 0.0025 18.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Caps_synth PF05704.12 PVD33750.1 - 0.019 14.4 0.5 0.076 12.4 0.5 1.8 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein NAD1 PF18778.1 PVD33750.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 TcdA_TcdB PF12919.7 PVD33750.1 - 0.11 11.7 0.2 0.34 10.1 0.1 1.7 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Smac_DIABLO PF09057.10 PVD33751.1 - 1.1e-24 87.1 8.5 1.3e-24 86.8 8.5 1.0 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases RhoGEF PF00621.20 PVD33751.1 - 0.066 13.4 2.0 0.11 12.7 2.0 1.4 1 1 0 1 1 1 0 RhoGEF domain AbbA_antirepres PF14156.6 PVD33751.1 - 0.083 12.8 0.7 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 Antirepressor AbbA PTS_IIA PF02255.16 PVD33751.1 - 0.26 11.3 6.3 4.2 7.5 1.7 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Arf PF00025.21 PVD33752.1 - 3e-37 127.7 0.1 3e-37 127.7 0.1 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 PVD33752.1 - 0.0041 16.7 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 PVD33752.1 - 0.046 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 PVD33752.1 - 0.091 11.7 0.1 0.16 10.9 0.1 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRM_1 PF00076.22 PVD33753.1 - 9.6e-13 47.8 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PVD33753.1 - 1.4e-06 28.1 4.1 3.5e-06 26.8 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PVD33753.1 - 0.0011 18.7 4.6 0.0011 18.7 4.6 2.0 2 0 0 2 2 2 1 Zinc knuckle TMEM220 PF15071.6 PVD33753.1 - 0.24 12.2 0.0 0.39 11.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane family 220, helix SWIRM-assoc_2 PF16496.5 PVD33753.1 - 8.1 5.2 16.7 14 4.4 16.7 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Chorein_N PF12624.7 PVD33754.1 - 5.5e-15 55.5 0.0 1.7e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Prenyltransf PF01255.19 PVD33754.1 - 0.065 12.7 1.5 0.27 10.7 0.0 2.5 3 0 0 3 3 3 0 Putative undecaprenyl diphosphate synthase HOOK PF05622.12 PVD33754.1 - 0.067 11.3 12.5 0.1 10.7 12.5 1.2 1 0 0 1 1 1 0 HOOK protein Tropomyosin_1 PF12718.7 PVD33754.1 - 5.3 7.2 16.1 11 6.1 16.1 1.5 1 0 0 1 1 1 0 Tropomyosin like PDZ PF00595.24 PVD33755.1 - 2.7e-59 197.5 4.3 1.5e-16 60.5 0.0 4.1 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 PVD33755.1 - 6.1e-31 106.1 4.5 4.7e-09 36.0 0.1 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 PVD33755.1 - 1.6e-19 70.0 2.0 7.9e-05 22.9 0.1 4.3 4 0 0 4 4 4 4 PDZ domain zf-RING_2 PF13639.6 PVD33755.1 - 2e-08 34.4 5.3 2e-08 34.4 5.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD33755.1 - 2.6e-08 33.5 6.2 2.6e-08 33.5 6.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD33755.1 - 1.1e-07 31.7 7.7 3.9e-07 30.0 7.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD33755.1 - 1.8e-07 30.9 5.3 1.8e-07 30.9 5.3 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD33755.1 - 5.2e-07 29.5 4.9 5.2e-07 29.5 4.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD33755.1 - 5.4e-07 29.4 3.9 5.4e-07 29.4 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 PVD33755.1 - 1.1e-06 29.2 0.4 2.9e-06 27.9 0.4 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger zf-rbx1 PF12678.7 PVD33755.1 - 0.00019 21.7 3.4 0.0012 19.1 3.4 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PVD33755.1 - 0.00024 21.2 5.5 0.00024 21.2 5.5 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 PVD33755.1 - 0.0017 18.1 1.6 0.005 16.6 1.6 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 PVD33755.1 - 0.0088 16.2 6.2 0.029 14.5 6.2 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 Sina PF03145.16 PVD33755.1 - 0.051 13.5 0.3 0.09 12.7 0.3 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-ANAPC11 PF12861.7 PVD33755.1 - 0.072 13.2 0.6 0.28 11.2 0.6 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF_2 PF15965.5 PVD33755.1 - 0.12 12.9 7.6 0.037 14.5 2.5 2.4 1 1 1 2 2 2 0 TRAF-like zinc-finger DZR PF12773.7 PVD33755.1 - 2.9 8.0 6.9 31 4.7 6.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 PVD33755.1 - 8.2 6.4 11.2 2.3 8.1 6.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Euplotes_phero PF05842.11 PVD33756.1 - 0.03 14.9 1.5 0.049 14.2 1.5 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein DUF4611 PF15387.6 PVD33756.1 - 0.051 13.8 1.2 0.051 13.8 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 PVD33756.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 FAM176 family Fusion_gly PF00523.18 PVD33757.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 zf-CXXC PF02008.20 PVD33758.1 - 1.5e-07 31.3 20.9 2.6e-07 30.5 20.9 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain D5_N PF08706.11 PVD33758.1 - 0.086 13.1 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 D5 N terminal like Atx10homo_assoc PF09759.9 PVD33759.1 - 0.00022 21.2 0.4 0.24 11.4 0.0 2.8 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 PVD33759.1 - 0.0027 17.6 0.4 8.2 6.3 0.0 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) Arm PF00514.23 PVD33759.1 - 0.0033 17.4 0.1 2.2 8.5 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PVD33759.1 - 0.0043 17.2 0.2 1.1 9.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat RIX1 PF08167.12 PVD33759.1 - 0.0071 16.1 0.1 0.42 10.3 0.0 2.3 1 1 1 2 2 2 1 rRNA processing/ribosome biogenesis Dymeclin PF09742.9 PVD33759.1 - 0.014 13.9 0.3 0.017 13.5 0.3 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DUF4042 PF13251.6 PVD33759.1 - 0.022 14.5 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) DUF5578 PF17741.1 PVD33759.1 - 0.026 13.9 0.3 0.063 12.7 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 PVD33759.1 - 0.05 14.1 2.8 0.47 11.0 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat V-ATPase_H_C PF11698.8 PVD33759.1 - 0.062 13.4 0.6 8.4 6.5 0.0 2.8 3 0 0 3 3 3 0 V-ATPase subunit H Plk4_PB2 PF18409.1 PVD33759.1 - 0.1 13.3 1.3 0.21 12.3 0.1 2.0 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Kinesin PF00225.23 PVD33761.1 - 2.2e-111 372.0 1.7 2.2e-111 372.0 1.7 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33761.1 - 1.1e-61 207.1 0.0 3e-61 205.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KASH_CCD PF14662.6 PVD33761.1 - 0.00017 21.5 24.1 0.00027 20.8 22.5 2.0 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 PVD33761.1 - 0.00038 19.5 23.6 0.011 14.6 12.5 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein ERM PF00769.19 PVD33761.1 - 0.00042 20.2 15.5 0.00042 20.2 15.5 2.5 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Phage_GP20 PF06810.11 PVD33761.1 - 0.00057 19.7 1.0 0.00057 19.7 1.0 3.3 2 1 0 3 3 3 1 Phage minor structural protein GP20 PKcGMP_CC PF16808.5 PVD33761.1 - 0.028 14.3 12.4 2.7 7.9 1.3 4.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 PVD33761.1 - 0.061 13.4 27.2 0.11 12.6 10.7 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 PVD33761.1 - 0.071 13.5 24.6 0.26 11.7 8.1 3.1 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 PVD33761.1 - 0.21 10.6 22.3 0.037 13.1 12.0 2.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Radial_spoke PF04712.12 PVD33761.1 - 0.22 10.4 4.1 0.34 9.8 4.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein AAA_13 PF13166.6 PVD33761.1 - 0.22 10.1 17.9 0.028 13.1 13.3 1.9 2 0 0 2 2 2 0 AAA domain HMMR_N PF15905.5 PVD33761.1 - 0.42 10.0 22.4 2 7.8 11.0 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 PVD33761.1 - 1.1 9.3 27.2 0.019 15.1 8.6 2.7 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 PVD33761.1 - 1.2 9.4 5.1 4.4 7.6 0.2 3.3 3 0 0 3 3 3 0 Haemolysin XhlA DUF5082 PF16888.5 PVD33761.1 - 1.3 9.3 20.6 14 5.9 0.8 4.5 3 1 1 4 4 3 0 Domain of unknown function (DUF5082) ABC_tran_CTD PF16326.5 PVD33761.1 - 1.8 8.8 17.7 0.17 12.2 3.8 3.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF724 PF05266.14 PVD33761.1 - 3.5 7.4 24.3 0.59 9.9 6.6 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF724) EzrA PF06160.12 PVD33761.1 - 3.5 5.7 18.5 65 1.5 18.5 2.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 PVD33761.1 - 4.5 7.4 34.6 1.8 8.7 13.4 3.4 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 PVD33761.1 - 4.6 7.6 13.4 3.4 8.1 1.5 3.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.10 PVD33761.1 - 6 7.1 23.6 1.5 9.1 3.8 3.3 2 1 1 3 3 2 0 Cortexillin I, coiled coil Rho_Binding PF08912.11 PVD33761.1 - 6.3 7.7 14.2 0.65 10.9 0.8 4.5 3 1 0 4 4 4 0 Rho Binding CENP-F_leu_zip PF10473.9 PVD33761.1 - 6.3 6.8 30.4 1.5 8.8 12.2 3.3 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 PVD33761.1 - 6.5 6.3 18.4 1.7 8.2 6.7 3.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fez1 PF06818.15 PVD33761.1 - 7.9 6.9 28.7 0.22 12.0 13.0 2.8 2 1 1 3 3 3 0 Fez1 Golgin_A5 PF09787.9 PVD33761.1 - 8.2 5.8 25.1 7.1 6.0 13.1 2.5 1 1 0 2 2 2 0 Golgin subfamily A member 5 Spectrin PF00435.21 PVD33761.1 - 8.4 6.9 16.1 2.1 8.9 4.2 3.1 1 1 2 3 3 3 0 Spectrin repeat Itfg2 PF15907.5 PVD33762.1 - 2e-120 401.8 0.1 9.6e-119 396.3 0.0 2.2 2 0 0 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 PVD33762.1 - 7.1e-08 32.5 0.1 0.05 13.7 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 PVD33762.1 - 2.2e-06 28.1 2.9 0.41 11.3 0.4 3.8 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHTB1_N PF14727.6 PVD33762.1 - 0.068 12.5 0.1 1.9 7.8 0.0 2.7 3 1 1 4 4 4 0 PTHB1 N-terminus FG-GAP PF01839.23 PVD33762.1 - 0.098 12.8 4.7 1.9 8.7 0.8 3.3 4 0 0 4 4 4 0 FG-GAP repeat rve PF00665.26 PVD33763.1 - 3e-09 37.1 0.0 5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PVD33763.1 - 0.0021 17.8 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 PVD33764.1 - 4.1e-10 39.5 0.0 7.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD33765.1 - 1.6e-13 50.7 0.0 1.2e-08 34.8 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.21 PVD33767.1 - 7.9e-50 169.7 0.0 1.9e-49 168.4 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Lectin_C PF00059.21 PVD33767.1 - 2.8e-14 53.8 0.2 8.5e-14 52.2 0.2 1.9 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 PVD33767.1 - 0.009 16.0 1.4 0.02 14.8 1.4 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PVD33767.1 - 0.011 15.7 2.3 0.023 14.6 1.3 2.0 2 0 0 2 2 2 0 PAN domain Isochorismatase PF00857.20 PVD33768.1 - 2.2e-25 89.8 0.0 3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Ras PF00071.22 PVD33769.1 - 8.4e-57 191.3 0.1 9.7e-57 191.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD33769.1 - 5.1e-21 75.1 0.0 7.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD33769.1 - 1.1e-10 41.2 0.0 1.3e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD33769.1 - 5.5e-07 29.3 0.2 3.4e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD33769.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD33769.1 - 0.00017 21.5 0.0 0.52 10.2 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 PVD33769.1 - 0.00035 20.4 0.4 0.0098 15.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 PVD33769.1 - 0.012 15.2 0.1 0.12 11.9 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 PVD33769.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.6 1 1 0 1 1 1 0 Septin CbiA PF01656.23 PVD33769.1 - 0.12 12.4 0.7 0.71 9.9 0.7 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ldh_1_N PF00056.23 PVD33769.1 - 0.14 12.2 0.1 0.75 9.9 0.0 2.0 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain AAA_16 PF13191.6 PVD33769.1 - 0.17 12.3 0.1 0.55 10.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 PVD33769.1 - 0.18 11.3 0.0 0.42 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 PVD33770.1 - 1.6e-16 60.2 0.7 1.6e-16 60.2 0.7 2.5 3 1 1 4 4 4 1 DnaJ domain SEP PF08059.13 PVD33771.1 - 1.3e-28 99.4 0.1 2.4e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 PVD33771.1 - 1.6e-11 43.9 0.2 2.8e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 PVD33771.1 - 7.2e-08 32.5 0.1 8.3e-05 22.7 0.0 2.5 1 1 1 2 2 2 2 UBX domain TAP_C PF03943.13 PVD33771.1 - 6.5e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain RAP1 PF07218.11 PVD33771.1 - 7.4 4.7 6.9 10 4.3 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAR_3_WASP_bdg PF10456.9 PVD33772.1 - 2.4e-63 213.8 11.6 2e-41 142.0 0.9 2.1 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein SH3_9 PF14604.6 PVD33772.1 - 3.6e-12 46.0 0.2 6.5e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD33772.1 - 3.9e-12 45.6 0.3 8.9e-12 44.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD33772.1 - 1.2e-09 37.7 0.1 2.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PX PF00787.24 PVD33772.1 - 2.5e-05 24.2 0.0 5.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 PVD33772.1 - 0.0029 17.2 3.1 0.004 16.7 1.5 2.0 1 1 0 2 2 2 1 Vps5 C terminal like Talin_middle PF09141.10 PVD33772.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Talin, middle domain Bromodomain PF00439.25 PVD33774.1 - 1.4e-16 60.3 0.1 4.8e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Bromodomain WSD PF15613.6 PVD33774.1 - 0.0022 18.4 0.2 0.0022 18.4 0.2 4.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Pox_Ag35 PF03286.14 PVD33774.1 - 0.0045 16.8 7.2 0.0045 16.8 7.2 9.4 5 2 2 7 7 7 1 Pox virus Ag35 surface protein WHIM1 PF15612.6 PVD33774.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF4211 PF13926.6 PVD33775.1 - 1.6e-07 31.5 0.0 3.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Mob1_phocein PF03637.17 PVD33776.1 - 6.3e-55 185.8 1.5 8e-55 185.4 1.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF4451 PF14616.6 PVD33776.1 - 0.038 14.2 0.3 0.069 13.3 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) baeRF_family6 PF18848.1 PVD33776.1 - 0.13 12.7 0.4 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 Peptidase_C101 PF16218.5 PVD33777.1 - 1.9e-79 266.7 0.0 2.8e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C101 Ribosomal_L15e PF00827.17 PVD33777.1 - 0.00025 20.8 1.6 0.00042 20.1 1.6 1.4 1 0 0 1 1 1 1 Ribosomal L15 Peptidase_C65 PF10275.9 PVD33777.1 - 0.16 11.4 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase C65 Otubain Ribosomal_L15e PF00827.17 PVD33778.1 - 6.4e-47 159.7 3.6 8.3e-47 159.4 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L15 HECA PF15353.6 PVD33778.1 - 0.044 14.0 0.3 0.088 13.0 0.3 1.5 1 0 0 1 1 1 0 Headcase protein family homologue Amidohydro_1 PF01979.20 PVD33779.1 - 3e-60 204.4 0.9 7.6e-31 107.7 0.4 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 PVD33779.1 - 1.5e-25 90.6 8.7 4.8e-07 29.6 0.0 5.2 4 2 1 5 5 5 4 Amidohydrolase family Amidohydro_2 PF04909.14 PVD33779.1 - 3.4e-05 23.8 0.4 0.095 12.5 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase AP_endonuc_2 PF01261.24 PVD33779.1 - 0.0028 17.1 0.1 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Motile_Sperm PF00635.26 PVD33779.1 - 0.0036 17.1 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 2 MSP (Major sperm protein) domain Tfb2_C PF18307.1 PVD33779.1 - 0.092 13.2 1.2 3.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain Usp PF00582.26 PVD33779.1 - 0.17 12.4 0.2 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 Universal stress protein family Methyltransf_4 PF02390.17 PVD33780.1 - 5e-28 97.7 0.5 8e-26 90.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase BTB_2 PF02214.22 PVD33781.1 - 1.5e-06 28.5 0.1 1.4e-05 25.3 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Adeno_E3A PF05248.12 PVD33781.1 - 0.16 12.0 0.0 9.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Adenovirus E3A LytTR PF04397.15 PVD33783.1 - 0.033 14.4 0.1 0.071 13.3 0.1 1.6 1 1 0 1 1 1 0 LytTr DNA-binding domain Asp_protease PF09668.10 PVD33783.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2 PF00096.26 PVD33785.1 - 5.5e-10 39.1 27.3 9.4e-05 22.7 1.2 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD33785.1 - 3.2e-09 36.4 17.1 1.6e-07 31.0 4.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PVD33785.1 - 3.5e-07 30.5 18.1 0.0067 17.2 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD33785.1 - 8.5e-06 26.0 14.8 0.0031 17.8 0.0 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD33785.1 - 0.0052 17.0 13.1 0.018 15.4 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 PVD33785.1 - 0.008 14.8 1.4 1.2 7.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 PVD33785.1 - 0.017 15.1 0.4 0.017 15.1 0.4 2.5 3 0 0 3 3 2 0 C2H2-type zinc finger zf-met2 PF12907.7 PVD33785.1 - 0.054 13.7 0.9 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 PVD33785.1 - 0.12 12.0 7.7 6.6 6.5 0.1 3.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_7 PF15269.6 PVD33785.1 - 0.17 12.0 4.3 0.074 13.2 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger PyrI_C PF02748.15 PVD33785.1 - 0.22 11.5 3.9 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rpr2 PF04032.16 PVD33785.1 - 0.23 11.8 9.2 0.52 10.6 1.0 3.4 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.15 PVD33785.1 - 0.31 11.1 13.0 0.65 10.1 0.2 3.3 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 PVD33785.1 - 0.34 11.3 11.1 3.1 8.2 3.8 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 PVD33785.1 - 2 8.2 5.5 0.42 10.3 0.8 2.1 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zinc_ribbon_15 PF17032.5 PVD33785.1 - 3 8.6 14.2 0.9 10.3 3.5 3.3 2 1 2 4 4 4 0 zinc-ribbon family zf-met PF12874.7 PVD33785.1 - 6.3 7.3 13.5 11 6.6 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NAD_binding_4 PF07993.12 PVD33786.1 - 4e-77 258.9 0.0 5.9e-77 258.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 PVD33786.1 - 1.5e-34 118.1 0.2 4.5e-34 116.5 0.2 1.9 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 PVD33786.1 - 3.1e-07 30.1 0.0 7e-06 25.7 0.0 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PVD33786.1 - 3.7e-05 23.0 0.0 7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PVD33786.1 - 0.0027 16.7 1.6 0.012 14.7 0.8 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PVD33786.1 - 0.03 13.4 0.1 0.21 10.6 0.2 2.2 3 0 0 3 3 3 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PVD33786.1 - 0.13 11.7 0.0 0.42 9.9 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PVD33786.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAM25 PF15825.5 PVD33787.1 - 0.68 10.3 4.4 0.2 12.0 0.5 2.1 2 0 0 2 2 2 0 FAM25 family TNFR_c6 PF00020.18 PVD33788.1 - 3.2e-07 30.6 6.3 9.2e-07 29.2 6.3 1.9 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region ECSCR PF15820.5 PVD33788.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 PVD33788.1 - 0.042 14.7 0.2 0.9 10.5 0.1 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Choline_kinase PF01633.20 PVD33789.1 - 3.7e-55 186.8 0.4 7.6e-29 100.8 0.2 2.8 2 1 1 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 PVD33789.1 - 3.9e-10 40.0 0.3 2.5e-07 30.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 PVD33789.1 - 0.0015 17.9 0.8 0.046 13.0 0.2 2.2 1 1 1 2 2 2 2 Ecdysteroid kinase Thioredoxin PF00085.20 PVD33790.1 - 2.4e-06 27.5 0.2 3.7e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 PVD33790.1 - 7.7e-06 25.0 0.3 8.7e-06 24.9 0.3 1.1 1 0 0 1 1 1 1 Phosducin Pentapeptide_4 PF13599.6 PVD33790.1 - 0.047 13.9 0.4 0.7 10.1 0.4 2.1 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) HyaE PF07449.11 PVD33790.1 - 0.068 13.1 0.1 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Anthrax_toxA PF03497.16 PVD33790.1 - 0.091 12.9 1.1 0.5 10.5 0.3 2.0 2 0 0 2 2 2 0 Anthrax toxin LF subunit Cor1 PF04803.12 PVD33791.1 - 3.1e-45 153.6 29.2 4.4e-45 153.1 29.2 1.2 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region Rsa3 PF14615.6 PVD33791.1 - 0.19 11.3 1.5 2.3 7.9 0.1 2.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 hDGE_amylase PF14701.6 PVD33791.1 - 0.46 9.5 8.9 0.63 9.1 8.9 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Exonuc_VII_L PF02601.15 PVD33791.1 - 1.3 8.5 11.7 1.8 8.0 11.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4047 PF13256.6 PVD33791.1 - 3.1 8.0 11.2 2.9 8.1 9.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) MFS_1 PF07690.16 PVD33792.1 - 9.6e-46 156.3 26.8 4.6e-43 147.5 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD33792.1 - 2.3e-07 30.1 2.4 2.3e-07 30.1 2.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 PVD33792.1 - 0.00012 20.5 0.1 0.044 12.0 0.1 2.4 2 0 0 2 2 2 2 BT1 family Ldr_toxin PF13940.6 PVD33792.1 - 0.029 14.4 1.4 0.11 12.6 1.4 2.0 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system A_deamin PF02137.18 PVD33793.1 - 1.3e-79 268.1 0.0 1.7e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 PVD33793.1 - 1.4e-12 48.2 0.0 2.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ank_2 PF12796.7 PVD33794.1 - 1.1e-23 83.6 0.1 2.8e-17 63.1 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33794.1 - 5.9e-14 51.8 0.0 6.7e-06 26.3 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PVD33794.1 - 7.3e-14 51.9 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD33794.1 - 1.5e-13 49.6 0.0 9.3e-06 25.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD33794.1 - 8.9e-11 41.8 0.0 4e-05 23.8 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ribosomal_S9 PF00380.19 PVD33795.1 - 1.1e-33 116.3 0.2 1.3e-33 116.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Thymidylat_synt PF00303.19 PVD33796.1 - 7.5e-114 379.4 0.0 8.8e-114 379.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Ferritin_2 PF13668.6 PVD33796.1 - 0.099 12.8 0.0 20 5.3 0.0 2.2 2 0 0 2 2 2 0 Ferritin-like domain tRNA_int_endo_N PF02778.14 PVD33796.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain N_BRCA1_IG PF16158.5 PVD33797.1 - 4e-32 111.0 0.1 7.6e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 PVD33797.1 - 9.6e-11 41.3 0.1 1.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain CARDB PF07705.11 PVD33797.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 CARDB TAP_C PF03943.13 PVD33797.1 - 0.063 12.9 0.3 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 TAP C-terminal domain CoaE PF01121.20 PVD33798.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase SDA1 PF05285.12 PVD33798.1 - 5.9 6.2 13.1 8.6 5.7 13.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PVD33798.1 - 6.7 4.8 12.3 9 4.4 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 PVD33799.1 - 7e-71 239.5 0.8 7e-71 239.5 0.8 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 PVD33799.1 - 2.9e-45 153.1 1.6 2.9e-45 153.1 1.6 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 PVD33799.1 - 3.1e-05 24.7 0.1 3.1e-05 24.7 0.1 2.7 3 1 0 3 3 3 1 PF16858 Cnd2 PF05786.14 PVD33799.1 - 8.5e-05 21.4 5.3 0.00031 19.6 0.4 2.3 2 0 0 2 2 2 2 Condensin complex subunit 2 Rad21_Rec8_N PF04825.13 PVD33799.1 - 0.013 15.6 1.9 0.014 15.6 0.1 1.9 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein bPH_1 PF08000.11 PVD33799.1 - 0.071 13.2 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Bacterial PH domain TnpV PF14198.6 PVD33799.1 - 0.098 12.6 1.7 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV LRR_8 PF13855.6 PVD33800.1 - 3.8e-34 116.3 21.6 1.5e-08 34.3 2.2 7.6 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PVD33800.1 - 9.6e-18 64.0 45.0 0.00034 20.9 0.9 9.3 5 2 5 10 10 9 7 Leucine Rich repeats (2 copies) Roc PF08477.13 PVD33800.1 - 1.6e-13 51.0 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD33800.1 - 2.5e-10 40.2 0.0 4.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ras family COR PF16095.5 PVD33800.1 - 1.9e-09 37.6 0.6 1.5e-08 34.7 0.6 2.2 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 PVD33800.1 - 0.00011 21.7 0.2 0.00022 20.7 0.2 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_9 PF14580.6 PVD33800.1 - 0.00012 21.6 16.5 0.026 14.0 3.1 4.3 1 1 2 3 3 3 3 Leucine-rich repeat SRPRB PF09439.10 PVD33800.1 - 0.00027 20.4 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PVD33800.1 - 0.00075 19.0 0.4 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD33800.1 - 0.0029 17.7 0.0 0.009 16.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase LRR_1 PF00560.33 PVD33800.1 - 0.0062 16.9 38.1 9.1 7.3 0.1 12.3 13 1 0 13 13 13 2 Leucine Rich Repeat TniB PF05621.11 PVD33800.1 - 0.035 13.5 0.2 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PVD33800.1 - 0.087 12.7 0.9 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase GAIN PF16489.5 PVD33800.1 - 0.09 12.2 0.1 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain LMF1 PF06762.14 PVD33801.1 - 1.1e-94 318.1 0.0 1.4e-94 317.7 0.0 1.1 1 0 0 1 1 1 1 Lipase maturation factor TPR_2 PF07719.17 PVD33802.1 - 1.4e-19 68.5 10.2 0.00067 19.6 0.0 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD33802.1 - 8.1e-19 66.6 2.2 0.00033 20.3 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD33802.1 - 3.3e-14 51.8 9.9 0.25 11.5 0.0 9.2 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD33802.1 - 3.5e-13 49.2 6.5 0.18 12.7 0.1 8.0 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33802.1 - 1.6e-12 46.5 0.4 0.25 11.6 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD33802.1 - 7.8e-12 45.3 20.2 0.01 16.1 1.8 7.1 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 PVD33802.1 - 1e-07 32.4 7.4 0.001 19.6 0.2 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD33802.1 - 5.9e-07 29.1 2.0 2.6 7.8 0.0 6.9 5 1 2 7 7 7 2 TPR repeat TPR_10 PF13374.6 PVD33802.1 - 8.5e-06 25.5 21.0 0.018 14.9 0.1 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD33802.1 - 1.1e-05 25.8 8.7 0.13 12.8 0.1 5.2 3 2 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD33802.1 - 6.9e-05 23.0 10.7 2.1 8.9 0.1 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_5 PF12688.7 PVD33802.1 - 0.0033 17.6 0.6 1.6 9.0 0.0 4.1 3 1 1 4 4 4 1 Tetratrico peptide repeat TPR_6 PF13174.6 PVD33802.1 - 0.011 16.3 0.2 86 4.1 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 PVD33802.1 - 1.5 9.0 6.5 30 4.9 0.0 4.7 6 1 0 6 6 4 0 Tetratricopeptide repeat ETX_MTX2 PF03318.13 PVD33803.1 - 1.1e-09 38.5 6.8 1.3e-09 38.1 6.8 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 YscJ_FliF PF01514.17 PVD33803.1 - 0.067 12.8 1.4 0.11 12.1 1.4 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family DUF4288 PF14119.6 PVD33803.1 - 0.27 11.7 2.5 14 6.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) RRM_1 PF00076.22 PVD33804.1 - 2.5e-08 33.6 0.0 1.3e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LIM PF00412.22 PVD33805.1 - 6.1e-39 132.1 47.9 3e-15 56.2 10.3 3.1 3 0 0 3 3 3 3 LIM domain DUF2616 PF11077.8 PVD33805.1 - 0.0014 18.3 16.8 0.016 14.9 0.6 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2616) zf_UBZ PF18439.1 PVD33805.1 - 0.015 14.9 0.8 0.015 14.9 0.8 6.6 6 1 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_12 PF11331.8 PVD33805.1 - 3.6 7.5 29.4 0.28 11.0 2.3 4.7 4 1 1 5 5 5 0 Probable zinc-ribbon domain DUF4428 PF14471.6 PVD33805.1 - 4.8 7.2 14.9 1.7 8.6 0.7 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) Endonuclease_NS PF01223.23 PVD33807.1 - 0.00046 20.1 0.2 0.012 15.4 0.1 2.3 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease Cupin_8 PF13621.6 PVD33808.1 - 5.4e-57 193.4 0.5 6e-49 167.1 0.2 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 PVD33808.1 - 0.0085 16.5 0.7 0.026 15.0 0.7 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase NAD_binding_4 PF07993.12 PVD33809.1 - 6.7e-67 225.4 0.0 4e-64 216.3 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein Sterile PF03015.19 PVD33809.1 - 1.9e-32 111.3 0.8 3.6e-32 110.5 0.8 1.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 PVD33809.1 - 0.002 17.2 0.4 0.011 14.7 0.4 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PVD33809.1 - 0.0047 16.4 0.0 0.29 10.5 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Caleosin PF05042.13 PVD33809.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Caleosin related protein p53-inducible11 PF14936.6 PVD33810.1 - 5.3e-27 95.0 4.1 1.5e-14 54.4 0.1 2.0 1 1 1 2 2 2 2 Tumour protein p53-inducible protein 11 TMEM154 PF15102.6 PVD33814.1 - 0.0027 17.6 0.8 0.005 16.8 0.0 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF2367 PF10164.9 PVD33814.1 - 0.004 17.6 5.0 0.0068 16.9 0.9 2.6 1 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2367) PRIMA1 PF16101.5 PVD33814.1 - 0.012 15.7 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Halogen_Hydrol PF10112.9 PVD33814.1 - 0.013 15.5 0.0 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LapA_dom PF06305.11 PVD33814.1 - 0.029 14.2 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 PVD33814.1 - 0.038 14.9 0.0 0.091 13.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cytidylate_kin2 PF13189.6 PVD33814.1 - 0.062 13.4 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family Glycophorin_A PF01102.18 PVD33814.1 - 0.072 13.3 2.0 0.3 11.3 2.0 2.0 1 1 0 1 1 1 0 Glycophorin A SID-1_RNA_chan PF13965.6 PVD33814.1 - 0.19 10.1 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ECSCR PF15820.5 PVD33814.1 - 0.21 11.4 6.1 0.18 11.7 1.6 2.9 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator GNVR PF13807.6 PVD33814.1 - 0.29 11.1 3.1 3 7.8 1.7 2.4 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Vpu PF00558.19 PVD33814.1 - 0.3 10.9 0.6 2.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Vpu protein ATP1G1_PLM_MAT8 PF02038.16 PVD33814.1 - 8 6.0 9.0 0.21 11.1 0.3 2.6 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family LapA_dom PF06305.11 PVD33816.1 - 0.21 11.4 0.4 0.4 10.5 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 PVD33817.1 - 0.075 13.9 0.2 0.35 11.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.17 PVD33819.1 - 0.049 13.8 0.7 0.9 9.7 0.2 2.3 2 1 0 2 2 2 0 Immunoglobulin V-set domain S_4TM PF18159.1 PVD33819.1 - 0.098 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Ig_3 PF13927.6 PVD33819.1 - 0.22 12.1 5.2 11 6.8 0.3 3.0 2 1 0 2 2 2 0 Immunoglobulin domain OSTbeta PF15048.6 PVD33820.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein EGF_MSP1_1 PF12946.7 PVD33820.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 Ig_3 PF13927.6 PVD33820.1 - 0.35 11.5 3.2 12 6.6 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin domain RIFIN PF02009.16 PVD33823.1 - 6.4e-05 23.0 0.1 8.8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 PVD33823.1 - 0.00026 20.9 2.2 0.00052 19.9 2.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF2207 PF09972.9 PVD33823.1 - 0.01 14.6 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OAD_gamma PF04277.13 PVD33823.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Orf78 PF06024.12 PVD33823.1 - 0.021 15.1 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 PVD33823.1 - 0.021 15.7 0.0 0.057 14.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 PVD33823.1 - 0.024 14.0 1.5 0.047 13.1 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sigma_reg_N PF13800.6 PVD33823.1 - 0.037 14.3 0.2 0.82 10.0 0.0 2.5 2 1 0 2 2 2 0 Sigma factor regulator N-terminal Podoplanin PF05808.11 PVD33823.1 - 0.049 13.7 5.7 0.095 12.8 5.7 1.5 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 PVD33823.1 - 0.078 12.7 1.1 0.13 12.0 1.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4311 PF14188.6 PVD33823.1 - 0.13 12.0 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) MSC PF09402.10 PVD33823.1 - 0.14 11.6 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DAG1 PF05454.11 PVD33823.1 - 0.69 9.2 6.2 0.053 12.9 0.5 2.0 2 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Insulin_TMD PF17870.1 PVD33823.1 - 2.3 8.4 5.8 0.24 11.5 1.4 1.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Stevor PF17410.2 PVD33825.1 - 0.046 13.3 0.6 0.083 12.4 0.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PVD33825.1 - 0.057 14.3 0.0 0.15 12.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3533 PF12051.8 PVD33825.1 - 0.059 12.3 6.5 0.09 11.7 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Amnionless PF14828.6 PVD33825.1 - 0.064 12.1 0.1 0.12 11.2 0.1 1.5 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 PVD33825.1 - 0.076 12.9 1.2 0.11 12.3 1.2 1.2 1 0 0 1 1 1 0 Rifin DUF1180 PF06679.12 PVD33825.1 - 0.13 12.7 5.0 0.1 13.0 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) FeoB_associated PF12669.7 PVD33825.1 - 0.4 11.1 1.1 1.1 9.7 1.1 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Aldo_ket_red PF00248.21 PVD33826.1 - 4.9e-40 137.5 0.0 5.3e-39 134.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.31 PVD33827.1 - 6.2e-13 48.9 0.1 1e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 PVD33828.1 - 1.5e-09 37.8 43.2 5.1e-06 26.7 1.4 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD33828.1 - 2.3e-06 28.0 51.8 0.014 16.2 0.7 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD33828.1 - 0.00035 20.9 53.2 0.0039 17.6 6.6 6.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PVD33828.1 - 0.0013 18.4 0.8 0.0013 18.4 0.8 3.9 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 PVD33828.1 - 0.11 13.2 16.4 0.27 12.0 1.9 3.0 2 1 1 3 3 3 0 zinc-ribbon family Actin_micro PF17003.5 PVD33828.1 - 1.4 8.0 21.5 0.98 8.5 0.0 3.9 1 1 2 3 3 3 0 Putative actin-like family DZR PF12773.7 PVD33828.1 - 5.1 7.2 19.4 2e+02 2.1 11.6 3.7 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 PVD33828.1 - 5.3 7.4 25.4 0.76 10.1 4.5 4.6 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 PVD33828.1 - 7.3 6.7 13.0 4.6 7.3 0.0 3.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-LITAF-like PF10601.9 PVD33828.1 - 7.4 6.9 14.2 3.2 8.1 6.6 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain p450 PF00067.22 PVD33829.1 - 6e-29 101.1 0.0 1.5e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Guanylate_cyc PF00211.20 PVD33830.1 - 1e-57 194.8 0.1 6.2e-57 192.2 0.1 2.2 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 PVD33830.1 - 2.9e-41 141.7 0.1 3.6e-40 138.2 0.5 2.0 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD33830.1 - 5.9e-28 97.8 0.0 6.5e-20 71.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD33830.1 - 1.8e-25 89.8 0.0 4.4e-20 72.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Peripla_BP_6 PF13458.6 PVD33830.1 - 2.3e-08 34.1 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein HNOBA PF07701.14 PVD33830.1 - 6.9e-06 25.6 0.7 1.2e-05 24.8 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Spatacsin_C PF14649.6 PVD33830.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Spatacsin C-terminus HCNGP PF07818.13 PVD33831.1 - 2.8e-24 85.6 2.5 7.4e-24 84.2 2.5 1.7 1 0 0 1 1 1 1 HCNGP-like protein Kinesin PF00225.23 PVD33832.1 - 1.1e-108 363.1 0.1 1.1e-108 363.1 0.1 3.5 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33832.1 - 6.2e-26 91.1 0.0 6.2e-26 91.1 0.0 3.1 3 1 1 4 4 4 1 Microtubule binding Acetyltransf_1 PF00583.25 PVD33833.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Sulfatase_C PF14707.6 PVD33834.1 - 1.8e-05 25.5 0.1 2.1e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase C1q PF00386.21 PVD33836.1 - 6.2e-07 29.7 0.1 1.3e-06 28.7 0.0 1.5 2 0 0 2 2 2 1 C1q domain Sema PF01403.19 PVD33836.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Sema domain DUF5528 PF17666.1 PVD33837.1 - 1.1e-07 31.9 1.6 2.3e-07 30.9 0.9 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5528) BBS2_C PF14782.6 PVD33838.1 - 2.8e-181 603.0 1.1 3.1e-180 599.6 1.1 2.3 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 PVD33838.1 - 6.6e-43 145.2 0.3 2.2e-42 143.4 0.1 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 PVD33838.1 - 9e-39 131.6 0.0 7.5e-38 128.6 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal DUF2152 PF10222.9 PVD33839.1 - 5.8e-155 517.0 8.3 1.8e-89 300.8 3.3 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.15 PVD33839.1 - 0.0014 18.4 0.4 0.083 12.5 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain HMG_box PF00505.19 PVD33840.1 - 1.7e-24 86.0 3.9 1.7e-24 86.0 3.9 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD33840.1 - 8.6e-09 35.9 1.5 1.8e-08 34.8 1.5 1.6 1 0 0 1 1 1 1 HMG-box domain AP3D1 PF06375.11 PVD33842.1 - 0.014 15.6 0.7 0.014 15.6 0.7 1.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 YdjO PF14169.6 PVD33842.1 - 0.74 9.6 3.8 4.4 7.1 0.7 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Aminotran_4 PF01063.19 PVD33847.1 - 5.8e-11 42.7 0.0 8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 PVD33848.1 - 2.2e-28 99.6 0.0 2.9e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV PAS_11 PF14598.6 PVD33849.1 - 1.2e-27 96.3 1.7 8e-23 80.7 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 PVD33849.1 - 1.6e-20 73.2 0.1 1.9e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 PVD33849.1 - 1.8e-17 63.3 0.0 2.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 PVD33849.1 - 6.3e-16 58.1 1.8 1.3e-15 57.1 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 PVD33849.1 - 5.1e-09 36.3 0.0 2.8e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 PVD33849.1 - 0.00011 22.4 0.0 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 PVD33849.1 - 0.0027 18.4 0.0 0.017 15.7 0.0 2.4 4 0 0 4 4 4 1 PAS fold C2 PF00168.30 PVD33850.1 - 2e-21 76.2 0.0 4.6e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 PVD33850.1 - 0.00015 22.3 2.4 0.95 10.1 0.1 3.9 4 0 0 4 4 4 2 Putative heavy-metal-binding Peptidase_M54 PF07998.11 PVD33851.1 - 1.6e-07 31.5 0.1 2.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 NAD_binding_10 PF13460.6 PVD33851.1 - 6.1e-06 26.2 0.0 8.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 PVD33851.1 - 0.0053 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 PVD33851.1 - 0.03 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kinesin PF00225.23 PVD33852.1 - 5.5e-91 305.0 0.5 5.5e-91 305.0 0.5 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33852.1 - 1.9e-23 83.1 0.0 5.4e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Ferritin PF00210.24 PVD33853.1 - 3e-30 105.0 0.5 5.3e-30 104.2 0.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain CBFB_NFYA PF02045.15 PVD33853.1 - 6.1e-26 90.8 7.9 1.1e-25 89.9 7.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Coprogen_oxidas PF01218.18 PVD33853.1 - 0.011 14.5 2.0 0.018 13.7 2.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase RCC1 PF00415.18 PVD33854.1 - 9.6e-54 179.8 12.7 2.5e-14 53.6 0.2 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD33854.1 - 1.5e-34 117.1 25.0 2.2e-09 36.8 0.9 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Amnionless PF14828.6 PVD33855.1 - 0.049 12.5 0.1 0.049 12.5 0.1 1.1 1 0 0 1 1 1 0 Amnionless PepSY_TM PF03929.16 PVD33855.1 - 0.058 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Glycophorin_A PF01102.18 PVD33855.1 - 4.7 7.5 8.7 45 4.3 8.7 2.1 1 1 0 1 1 1 0 Glycophorin A SKG6 PF08693.10 PVD33857.1 - 0.13 11.7 1.2 0.74 9.3 1.2 2.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 PVD33858.1 - 2.8e-10 40.2 3.4 0.00042 20.2 0.4 2.8 2 0 0 2 2 2 2 TMEM154 protein family EphA2_TM PF14575.6 PVD33858.1 - 6.1e-07 30.2 3.1 0.059 14.2 0.0 3.1 2 1 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PVD33858.1 - 0.00015 22.0 0.3 0.64 10.3 0.0 3.1 2 0 0 2 2 2 2 Orf78 (ac78) Protocadherin PF08374.11 PVD33858.1 - 0.00019 21.5 8.7 0.003 17.6 0.1 2.9 3 0 0 3 3 2 2 Protocadherin DUF1180 PF06679.12 PVD33858.1 - 0.0002 21.8 4.5 0.076 13.4 0.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) Shisa PF13908.6 PVD33858.1 - 0.00065 20.0 3.7 0.63 10.3 0.1 3.5 3 0 0 3 3 2 2 Wnt and FGF inhibitory regulator DAG1 PF05454.11 PVD33858.1 - 0.0017 17.8 0.6 0.58 9.5 0.0 2.5 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Glycophorin_A PF01102.18 PVD33858.1 - 0.0025 18.1 1.6 2.5 8.4 0.0 3.3 3 0 0 3 3 2 1 Glycophorin A Stevor PF17410.2 PVD33858.1 - 0.003 17.1 0.6 1.4 8.4 0.1 2.5 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 PVD33858.1 - 0.003 17.4 10.9 0.12 12.4 0.6 2.8 3 0 0 3 3 2 2 Syndecan domain DUF5385 PF17359.2 PVD33858.1 - 0.0042 16.7 1.0 2.8 7.5 0.1 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5385) TrbL PF04610.14 PVD33858.1 - 0.008 16.0 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein Cadherin_C_2 PF16492.5 PVD33858.1 - 0.01 16.6 0.0 3.4 8.5 0.0 3.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DAP10 PF07213.11 PVD33858.1 - 0.014 15.3 5.9 0.53 10.3 0.2 3.3 3 0 0 3 3 3 0 DAP10 membrane protein DUF2207 PF09972.9 PVD33858.1 - 0.015 14.1 0.8 3.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 PVD33858.1 - 0.022 15.0 0.0 6.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3377 PF11857.8 PVD33858.1 - 0.029 14.3 3.6 1 9.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) W_rich_C PF07483.11 PVD33858.1 - 0.033 14.3 0.0 14 5.9 0.0 3.1 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain RIFIN PF02009.16 PVD33858.1 - 0.033 14.1 12.6 0.28 11.1 0.1 3.3 4 0 0 4 4 2 0 Rifin DUF4199 PF13858.6 PVD33858.1 - 0.036 14.5 0.1 4 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Vpu PF00558.19 PVD33858.1 - 0.04 13.7 0.5 6.9 6.5 0.1 2.9 2 0 0 2 2 2 0 Vpu protein DUF2062 PF09835.9 PVD33858.1 - 0.043 13.7 0.1 5 7.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF202 PF02656.15 PVD33858.1 - 0.048 14.1 0.7 16 6.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) 7TM_GPCR_Srv PF10323.9 PVD33858.1 - 0.074 12.4 1.2 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4381 PF14316.6 PVD33858.1 - 0.1 12.8 0.0 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3367 PF11847.8 PVD33858.1 - 0.11 10.3 2.9 4 5.2 0.1 2.1 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase DUF1345 PF07077.11 PVD33858.1 - 0.12 12.1 2.6 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF4690 PF15756.5 PVD33858.1 - 0.37 11.4 10.7 0.15 12.7 0.5 3.6 3 0 0 3 3 2 0 Small Novel Rich in Cartilage CcmD PF04995.14 PVD33858.1 - 0.94 9.6 6.6 12 6.1 0.5 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MerT PF02411.15 PVD33858.1 - 1.2 9.2 4.3 2.4 8.2 0.4 2.4 2 0 0 2 2 2 0 MerT mercuric transport protein Podoplanin PF05808.11 PVD33858.1 - 1.3 9.1 10.4 0.084 13.0 0.6 3.1 3 0 0 3 3 2 0 Podoplanin Baculo_11_kDa PF06143.11 PVD33858.1 - 1.3 8.6 5.0 9.2 5.9 0.1 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family FeoB_associated PF12669.7 PVD33858.1 - 1.6 9.2 13.1 6.4 7.3 5.7 3.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Collectrin PF16959.5 PVD33858.1 - 2.8 7.7 9.0 8.3 6.2 1.6 2.5 2 0 0 2 2 2 0 Renal amino acid transporter RCR PF12273.8 PVD33858.1 - 5.6 7.7 11.2 3.2 8.4 0.0 3.5 2 2 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red MAM PF00629.23 PVD33859.1 - 8e-14 51.9 7.8 5.7e-12 45.8 0.1 3.8 3 1 0 3 3 3 2 MAM domain, meprin/A5/mu Syndecan PF01034.20 PVD33859.1 - 0.19 11.6 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 PVD33859.1 - 0.35 10.8 2.5 0.88 9.5 2.5 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 PVD33859.1 - 6.1 7.2 6.7 0.54 10.6 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sulfatase PF00884.23 PVD33860.1 - 7.5e-26 91.2 1.3 5.3e-13 49.0 0.0 3.1 1 1 2 3 3 3 3 Sulfatase Sulfatase_C PF14707.6 PVD33860.1 - 3.5e-06 27.7 0.0 6.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD33860.1 - 0.00017 21.4 0.3 0.00032 20.6 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function Sulfatase PF00884.23 PVD33861.1 - 2.6e-24 86.2 2.0 1.7e-12 47.4 0.0 3.2 2 1 1 3 3 3 3 Sulfatase Sulfatase_C PF14707.6 PVD33861.1 - 2.6e-05 24.9 0.0 5.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD33861.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function MAM PF00629.23 PVD33861.1 - 0.01 15.8 3.8 1.2 9.1 0.8 3.9 1 1 2 3 3 3 0 MAM domain, meprin/A5/mu DUF4834 PF16118.5 PVD33862.1 - 0.12 13.4 0.0 0.12 13.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 PVD33862.1 - 1.1 9.2 2.9 0.8 9.6 0.9 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 MAM PF00629.23 PVD33863.1 - 1.1e-21 77.5 2.6 3.2e-20 72.7 0.7 2.2 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 PVD33864.1 - 5.5e-05 23.1 0.6 0.021 14.7 0.6 2.8 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu DUF2615 PF11027.8 PVD33864.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF5385 PF17359.2 PVD33864.1 - 0.046 13.3 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Auxin_repressed PF05564.12 PVD33864.1 - 0.084 13.6 1.5 0.27 11.9 0.4 2.1 2 0 0 2 2 2 0 Dormancy/auxin associated protein DUF2500 PF10694.9 PVD33864.1 - 0.096 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) MAP17 PF15807.5 PVD33864.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Sulfatase PF00884.23 PVD33865.1 - 7.6e-42 143.8 0.3 9.1e-24 84.4 0.0 2.4 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.17 PVD33865.1 - 0.001 17.8 0.0 0.0015 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 PVD33865.1 - 0.013 14.6 0.4 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) RVT_1 PF00078.27 PVD33868.1 - 2.2e-23 82.9 0.0 5.6e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3291 PF11695.8 PVD33868.1 - 0.075 12.7 0.8 0.59 9.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3291) Exo_endo_phos_2 PF14529.6 PVD33869.1 - 4.2e-18 65.3 0.0 9.3e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD33869.1 - 6.4e-08 32.4 0.5 1.4e-07 31.3 0.5 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Streptin-Immun PF11083.8 PVD33869.1 - 0.076 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein SKG6 PF08693.10 PVD33870.1 - 1.9e-05 24.0 12.2 4.3e-05 22.8 12.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 PVD33870.1 - 0.00036 20.4 0.1 0.00055 19.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 PVD33870.1 - 0.0014 18.6 0.6 0.0014 18.6 0.6 1.8 2 0 0 2 2 2 1 TMEM154 protein family Shisa PF13908.6 PVD33870.1 - 0.0028 17.9 1.0 0.0046 17.2 1.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator GT87 PF09594.10 PVD33870.1 - 0.0036 17.0 0.1 0.0057 16.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 DUF2755 PF10954.8 PVD33870.1 - 0.004 17.0 0.3 0.0078 16.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2755) stn_TNFRSF12A PF12191.8 PVD33870.1 - 0.0042 17.3 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Peptidase_M56 PF05569.11 PVD33870.1 - 0.0078 15.4 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 Amnionless PF14828.6 PVD33870.1 - 0.0084 15.0 0.4 0.0094 14.8 0.4 1.1 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 PVD33870.1 - 0.0093 16.8 0.1 0.018 15.9 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 PVD33870.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2681 PF10883.8 PVD33870.1 - 0.028 14.8 0.1 0.058 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ABC_membrane PF00664.23 PVD33870.1 - 0.034 13.8 0.0 0.082 12.5 0.0 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region Orf78 PF06024.12 PVD33870.1 - 0.041 14.2 0.0 0.098 13.0 0.0 1.6 1 1 1 2 2 2 0 Orf78 (ac78) DUF485 PF04341.12 PVD33870.1 - 0.048 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF4381 PF14316.6 PVD33870.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5385 PF17359.2 PVD33870.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) GAPT PF11770.8 PVD33870.1 - 1.9 8.3 6.6 4.9 7.0 1.0 2.4 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) VSP PF03302.13 PVD33870.1 - 3 6.6 10.7 1.3 7.8 7.7 1.8 2 1 0 2 2 2 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 PVD33870.1 - 9.8 6.0 8.3 25 4.7 8.3 1.8 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 PVD33871.1 - 0.0015 18.5 0.1 0.0029 17.5 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PVD33871.1 - 0.0025 18.6 0.0 0.0048 17.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 PVD33871.1 - 0.011 14.6 0.1 0.011 14.6 0.1 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein DAG1 PF05454.11 PVD33871.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) FxsA PF04186.13 PVD33871.1 - 0.025 14.7 0.6 0.042 14.0 0.6 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein PTP_tm PF18861.1 PVD33871.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4366 PF14283.6 PVD33871.1 - 0.047 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4448 PF14610.6 PVD33871.1 - 0.062 13.1 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5305 PF17231.2 PVD33871.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Sulfatase PF00884.23 PVD33872.1 - 1.1e-57 195.8 1.2 1.6e-57 195.3 1.2 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 PVD33872.1 - 0.0002 22.1 0.0 0.00047 20.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 PVD33872.1 - 0.0098 15.8 0.0 0.035 14.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function Sulfate_transp PF00916.20 PVD33873.1 - 1.1e-60 205.4 17.9 7.1e-36 123.8 1.7 3.1 1 1 2 3 3 3 3 Sulfate permease family STAS PF01740.21 PVD33873.1 - 0.00037 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PVD33873.1 - 0.013 15.9 3.6 0.013 15.9 3.6 2.6 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily STAS PF01740.21 PVD33874.1 - 7.8e-14 51.3 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 PVD33875.1 - 1.3e-86 290.8 16.6 1.6e-86 290.4 16.6 1.0 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 PVD33875.1 - 0.0091 16.4 0.7 0.0091 16.4 0.7 3.2 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 PVD33877.1 - 2e-72 244.1 20.5 1e-71 241.7 20.5 1.8 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD33877.1 - 8.7e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PVD33877.1 - 0.00086 19.7 3.7 0.00086 19.7 3.7 3.2 2 1 2 4 4 4 1 Molybdate transporter of MFS superfamily STAS PF01740.21 PVD33878.1 - 8.1e-19 67.4 0.1 9.8e-19 67.1 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD33878.1 - 0.0015 18.8 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 PVD33879.1 - 4.1e-97 325.3 19.9 6.9e-97 324.6 19.9 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD33879.1 - 4.3e-05 23.1 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PVD33879.1 - 0.0086 16.5 3.8 0.0086 16.5 3.8 4.1 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF3382 PF11862.8 PVD33879.1 - 0.8 10.0 0.0 0.8 10.0 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3382) STAS PF01740.21 PVD33880.1 - 1.2e-17 63.6 0.0 1.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD33880.1 - 0.00055 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain Nsp1 PF11501.8 PVD33880.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 QVR PF17064.5 PVD33883.1 - 0.00076 19.7 5.9 0.0012 19.1 5.9 1.3 1 0 0 1 1 1 1 Sleepless protein zf-H2C2_2 PF13465.6 PVD33884.1 - 8.5e-12 44.9 45.9 3.2e-06 27.3 5.9 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD33884.1 - 2e-09 37.4 64.2 0.00068 20.0 7.9 6.9 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33884.1 - 2.7e-08 34.0 56.4 0.056 14.3 0.8 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD33884.1 - 6.3e-05 22.9 33.2 0.0013 18.6 0.8 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD33884.1 - 0.15 12.4 0.1 0.15 12.4 0.1 7.3 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 PVD33884.1 - 0.61 10.9 17.3 1.4 9.8 2.5 3.3 2 1 1 3 3 3 0 zinc-ribbon family zf-met PF12874.7 PVD33884.1 - 0.99 9.9 43.3 0.29 11.6 3.6 5.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 PVD33885.1 - 3.5e-20 71.5 27.5 9.4e-07 29.0 1.3 4.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD33885.1 - 3.5e-15 55.5 36.6 1.6e-05 25.1 3.8 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD33885.1 - 7.6e-12 45.0 32.6 0.011 16.5 2.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 PVD33885.1 - 1.5e-07 31.6 19.4 0.02 15.3 0.6 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD33885.1 - 0.00017 21.5 32.3 0.038 14.0 2.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger GAGA PF09237.11 PVD33885.1 - 0.014 15.2 5.2 1.2 9.0 0.6 3.2 1 1 2 3 3 3 0 GAGA factor Rtf2 PF04641.12 PVD33885.1 - 0.12 11.7 1.9 0.81 9.0 0.0 2.4 1 1 1 2 2 2 0 Rtf2 RING-finger BolA PF01722.18 PVD33885.1 - 0.19 12.0 4.2 2.3 8.5 1.3 2.5 1 1 1 2 2 2 0 BolA-like protein Vps39_2 PF10367.9 PVD33885.1 - 0.63 10.5 5.7 12 6.4 0.4 2.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Laminin_N PF00055.17 PVD33885.1 - 0.79 9.3 8.2 0.12 12.0 0.6 2.2 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) Zn-ribbon_8 PF09723.10 PVD33885.1 - 3.5 7.8 9.9 0.58 10.3 1.8 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 PVD33885.1 - 5.7 6.9 13.3 3.6 7.5 2.0 3.3 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 PVD33885.1 - 6.3 6.5 14.6 8.9 6.0 1.2 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CHY PF05495.12 PVD33885.1 - 8.6 6.9 18.7 11 6.6 10.9 2.7 1 1 0 2 2 2 0 CHY zinc finger DCX PF03607.17 PVD33887.1 - 3.1e-16 59.2 0.2 0.014 15.5 0.0 6.5 7 0 0 7 7 7 4 Doublecortin KHA PF11834.8 PVD33887.1 - 1.5e-11 44.2 0.0 0.12 12.5 0.0 5.6 5 0 0 5 5 5 3 KHA, dimerisation domain of potassium ion channel Ricin_B_lectin PF00652.22 PVD33887.1 - 2.6e-07 30.9 2.0 0.068 13.4 0.0 4.4 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain DUF4588 PF15251.6 PVD33887.1 - 0.00076 19.3 0.5 0.0027 17.5 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) FtsK_SpoIIIE_N PF12538.8 PVD33887.1 - 0.027 14.7 0.5 0.027 14.7 0.5 2.7 3 0 0 3 3 3 0 DNA transporter Arc_PepC_II PF06847.11 PVD33887.1 - 0.029 14.9 0.0 0.63 10.6 0.0 3.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Adaptin_N PF01602.20 PVD33888.1 - 1.1e-149 499.4 5.1 1.4e-149 499.1 5.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 PVD33888.1 - 5.1e-30 104.0 0.0 1.3e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 PVD33888.1 - 7.6e-07 29.4 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 PVD33888.1 - 3.2e-06 27.3 0.7 5.2e-05 23.3 0.0 2.6 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD33888.1 - 5e-05 23.6 3.7 0.088 13.2 0.1 5.0 3 2 2 6 6 6 1 HEAT repeats HEAT PF02985.22 PVD33888.1 - 0.0014 18.7 3.2 1.4e+02 3.1 0.1 6.3 5 1 1 6 6 6 0 HEAT repeat RIX1 PF08167.12 PVD33888.1 - 0.029 14.1 3.4 0.43 10.3 0.5 3.6 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Hormone_recep PF00104.30 PVD33889.1 - 3.2e-06 26.9 0.1 1.1e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD33890.1 - 3e-27 94.9 13.3 5.5e-27 94.0 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BPL_N PF09825.9 PVD33891.1 - 8.6e-60 202.8 0.0 1.1e-59 202.4 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.14 PVD33891.1 - 0.058 13.0 0.3 0.099 12.2 0.3 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain KGG PF10685.9 PVD33891.1 - 0.5 10.7 1.9 1.4 9.3 1.9 1.8 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Caprin-1_dimer PF18293.1 PVD33892.1 - 1.7e-38 131.6 0.1 4.2e-38 130.4 0.1 1.7 1 0 0 1 1 1 1 Caprin-1 dimerization domain Caprin-1_C PF12287.8 PVD33892.1 - 9.4e-09 35.9 46.9 9.4e-09 35.9 46.9 3.4 2 2 0 2 2 2 1 Cytoplasmic activation/proliferation-associated protein-1 C term Ank_2 PF12796.7 PVD33893.1 - 3.8e-23 81.9 4.7 0.00035 21.1 0.1 5.2 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD33893.1 - 3.5e-17 60.7 4.8 0.00057 20.1 0.0 6.2 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 PVD33893.1 - 5.3e-14 51.9 1.4 5e-05 23.5 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 PVD33893.1 - 5.6e-14 52.3 0.1 0.01 16.4 0.0 5.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD33893.1 - 5.2e-11 42.6 4.2 0.00026 21.2 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) B2-adapt-app_C PF09066.10 PVD33893.1 - 0.016 15.3 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Kinesin PF00225.23 PVD33894.1 - 7e-98 327.6 0.0 7e-98 327.6 0.0 3.1 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33894.1 - 1.5e-24 86.6 1.1 2.1e-23 82.9 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding WD40 PF00400.32 PVD33894.1 - 2.3e-18 66.2 6.1 0.0043 17.8 0.2 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Axin_b-cat_bind PF08833.10 PVD33894.1 - 0.11 12.7 2.3 0.46 10.6 2.3 2.1 1 0 0 1 1 1 0 Axin beta-catenin binding domain Pox_vIL-18BP PF05566.12 PVD33894.1 - 0.15 12.3 0.2 0.43 10.8 0.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein PsbK PF02533.15 PVD33895.1 - 0.31 11.2 0.2 0.31 11.2 0.2 1.6 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component Forkhead PF00250.18 PVD33896.1 - 1.3e-17 63.8 1.4 1.8e-17 63.3 1.4 1.2 1 0 0 1 1 1 1 Forkhead domain Innexin PF00876.18 PVD33897.1 - 1.5e-28 100.1 0.2 9.2e-22 77.8 0.0 2.0 1 1 1 2 2 2 2 Innexin RFX_DNA_binding PF02257.15 PVD33899.1 - 2.7e-13 50.3 1.6 9.3e-13 48.6 1.1 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain ALO PF04030.14 PVD33901.1 - 1.2e-92 310.4 2.7 1.5e-92 310.1 2.7 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PVD33901.1 - 2.5e-27 95.3 0.1 8.6e-27 93.6 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain OGFr_N PF04664.13 PVD33902.1 - 1.7e-77 259.7 5.1 2.2e-77 259.3 5.1 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region LRR_8 PF13855.6 PVD33903.1 - 1.6e-64 213.5 40.7 6.7e-15 54.6 1.2 6.9 2 2 4 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 PVD33903.1 - 2.5e-32 111.5 0.0 8e-10 38.8 0.0 3.8 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) 7tm_1 PF00001.21 PVD33903.1 - 3e-28 98.9 10.2 4.2e-28 98.4 10.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 PVD33903.1 - 4.9e-24 84.0 46.8 9.4e-05 22.7 0.1 9.8 5 3 6 12 12 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD33903.1 - 7.4e-11 41.9 17.4 0.00037 20.1 2.0 4.7 1 1 3 5 5 5 3 Leucine-rich repeat 7tm_4 PF13853.6 PVD33903.1 - 0.014 15.2 7.3 0.57 9.9 7.3 2.2 1 1 0 1 1 1 0 Olfactory receptor LRR_1 PF00560.33 PVD33903.1 - 0.041 14.4 32.4 1.9 9.4 0.1 10.7 12 0 0 12 12 10 0 Leucine Rich Repeat 7TM_GPCR_Srv PF10323.9 PVD33903.1 - 0.19 11.0 5.6 0.34 10.2 5.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Cir_Bir_Yir PF06022.11 PVD33903.1 - 0.26 10.7 0.5 0.44 10.0 0.5 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir SelP_N PF04592.14 PVD33903.1 - 5.6 6.3 11.4 16 4.8 11.4 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CT47 PF15623.6 PVD33903.1 - 7.5 6.3 8.1 0.27 11.1 1.1 2.0 2 0 0 2 2 2 0 Cancer/testis gene family 47 Bromodomain PF00439.25 PVD33904.1 - 4.7e-20 71.5 0.1 9.4e-20 70.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 PVD33904.1 - 7.3e-10 38.8 24.5 4.2e-07 30.0 9.6 4.8 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.29 PVD33904.1 - 2.1e-07 30.7 9.5 2.1e-07 30.7 9.5 4.7 5 1 0 5 5 5 1 PHD-finger zf-H3C2 PF16721.5 PVD33904.1 - 0.005 17.2 0.0 0.093 13.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger like, probable DNA-binding Glyco_transf_10 PF00852.19 PVD33905.1 - 7.9e-52 175.5 2.3 8.3e-52 175.5 0.4 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD33905.1 - 1.2e-14 54.6 0.8 2.3e-14 53.8 0.1 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_tran_10_N PF17039.5 PVD33906.1 - 2.4e-10 40.8 0.0 4.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD33906.1 - 4.1e-06 26.6 0.1 3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Sulfatase PF00884.23 PVD33907.1 - 1.3e-57 195.6 0.1 1.7e-57 195.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD33907.1 - 0.00011 22.4 0.0 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 PVD33907.1 - 0.00045 19.9 0.2 0.4 10.2 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfate_transp PF00916.20 PVD33908.1 - 1.4e-101 340.0 22.1 2.1e-101 339.5 22.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD33908.1 - 1.1e-23 83.1 0.0 2.5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD33908.1 - 0.0052 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain PI-PLC-X PF00388.19 PVD33909.1 - 1.5e-64 215.9 0.1 2.8e-64 215.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PVD33909.1 - 1.1e-23 83.8 0.3 3.1e-23 82.3 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 PVD33909.1 - 2.1e-15 57.0 0.0 5.3e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 PVD33909.1 - 6.5e-15 55.3 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 PVD33909.1 - 2.5e-14 54.0 0.0 8.8e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 PVD33909.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology SPT6_acidic PF14632.6 PVD33909.1 - 4.6 7.9 12.8 1.3 9.6 1.6 3.3 3 0 0 3 3 3 0 Acidic N-terminal SPT6 2-oxoacid_dh PF00198.23 PVD33910.1 - 3e-68 229.7 0.1 4.8e-68 229.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PVD33910.1 - 3.2e-17 62.1 0.7 3.2e-17 62.1 0.7 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 PVD33910.1 - 1.5e-05 25.2 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PVD33910.1 - 0.0035 17.2 0.0 0.0092 15.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 PVD33910.1 - 0.041 14.6 0.1 0.22 12.2 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.16 PVD33910.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Aldolase_II PF00596.21 PVD33911.1 - 3.3e-45 154.3 0.0 3.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ald_Xan_dh_C2 PF02738.18 PVD33912.1 - 1.7e-139 465.8 0.0 2.4e-139 465.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 PVD33912.1 - 1.2e-24 86.1 0.3 3.4e-24 84.7 0.1 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 PVD33912.1 - 5.1e-23 81.5 0.0 9.1e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PVD33912.1 - 2.7e-22 79.3 0.0 6.7e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD33912.1 - 6.8e-20 71.2 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PVD33912.1 - 0.0014 18.5 0.1 0.0057 16.6 0.1 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 PVD33912.1 - 0.1 12.7 0.1 0.46 10.6 0.1 2.2 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Elf1 PF05129.13 PVD33912.1 - 0.82 9.8 7.3 0.15 12.1 0.3 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Fic PF02661.18 PVD33915.1 - 1.3e-23 83.7 0.2 4.2e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family TPR_16 PF13432.6 PVD33915.1 - 5.7e-06 26.9 0.1 1.8e-05 25.3 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD33915.1 - 3.4e-05 23.7 0.1 0.16 12.3 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD33915.1 - 7e-05 22.6 0.1 0.01 15.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD33915.1 - 0.00015 21.4 0.1 0.027 14.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD33915.1 - 0.00057 20.5 1.2 0.0051 17.5 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD33915.1 - 0.0034 17.7 0.9 0.0093 16.2 0.9 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD33915.1 - 0.004 17.6 0.7 0.011 16.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD33915.1 - 0.004 17.0 0.3 0.019 14.9 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD33915.1 - 0.0062 16.2 0.0 0.036 13.8 0.0 2.3 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 PVD33915.1 - 0.0077 16.5 0.1 0.033 14.6 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD33915.1 - 0.044 13.8 0.1 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 PVD33916.1 - 5.1e-36 124.1 0.0 1.7e-35 122.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD33916.1 - 3.9e-24 85.1 0.0 1.1e-23 83.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD33916.1 - 5.3e-07 29.8 0.0 5.7e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PVD33916.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2726 PF10881.8 PVD33916.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) AAA_22 PF13401.6 PVD33916.1 - 0.26 11.6 1.6 6.6 7.0 1.6 2.7 1 1 0 1 1 1 0 AAA domain DUF5565 PF17720.1 PVD33917.1 - 5.9e-88 294.8 1.8 5.3e-83 278.6 0.2 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5565) DUF4207 PF13904.6 PVD33918.1 - 2e-05 24.4 24.5 2e-05 24.4 24.5 5.3 5 1 0 5 5 5 2 Domain of unknown function (DUF4207) DUF4532 PF15046.6 PVD33919.1 - 3.6e-33 114.9 2.5 6.3e-33 114.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4532) Syntaxin_2 PF14523.6 PVD33920.1 - 6.5e-23 81.0 15.9 7.7e-23 80.8 10.6 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Syntaxin PF00804.25 PVD33920.1 - 1e-07 31.8 19.6 4.4e-06 26.5 19.6 2.8 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 PVD33920.1 - 3.3e-07 30.2 0.3 3.3e-07 30.2 0.3 2.6 3 0 0 3 3 3 1 SNARE domain TMF_TATA_bd PF12325.8 PVD33920.1 - 0.049 13.9 16.7 0.2 11.9 8.6 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 PVD33920.1 - 0.064 13.5 6.9 5.8 7.2 2.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 PVD33920.1 - 0.065 13.7 9.4 0.089 13.3 9.4 1.2 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 PVD33920.1 - 0.094 13.4 0.4 0.094 13.4 0.4 3.4 2 1 1 3 3 3 0 SlyX Cnd1_N PF12922.7 PVD33920.1 - 0.54 10.1 4.7 0.23 11.3 2.2 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Fib_alpha PF08702.10 PVD33920.1 - 6.5 6.9 15.8 3.7 7.7 5.4 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Glycogen_syn PF05693.13 PVD33921.1 - 0 1129.5 0.0 0 1129.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 PVD33921.1 - 1.7e-06 27.9 0.2 1.1e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PVD33921.1 - 1.9e-05 24.3 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD33921.1 - 0.00017 22.0 0.0 0.0095 16.4 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PVD33921.1 - 0.00022 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 SPRY PF00622.28 PVD33922.1 - 3.6e-21 75.5 0.0 3.3e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 SPRY domain zf-RING_4 PF14570.6 PVD33923.1 - 1.3e-17 63.3 7.0 2.7e-17 62.3 7.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PVD33923.1 - 0.00015 21.6 3.9 0.00038 20.3 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 PVD33923.1 - 0.00035 20.3 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 PVD33923.1 - 0.0068 16.5 0.9 0.015 15.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Torus PF16131.5 PVD33923.1 - 0.0077 16.9 0.1 0.0077 16.9 0.1 2.3 3 0 0 3 3 3 1 Torus domain Vasculin PF15337.6 PVD33923.1 - 0.034 15.0 0.1 0.034 15.0 0.1 2.7 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 Nup35_RRM_2 PF14605.6 PVD33923.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.25 PVD33923.1 - 0.18 11.7 4.0 0.49 10.3 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD33923.1 - 0.25 11.2 4.7 0.75 9.7 4.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD33923.1 - 0.3 11.0 5.5 0.84 9.5 5.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-SCNM1 PF15803.5 PVD33924.1 - 2.5e-15 55.8 2.8 2.5e-15 55.8 2.8 2.2 2 0 0 2 2 2 1 Zinc-finger of sodium channel modifier 1 SCNM1_acidic PF15805.5 PVD33924.1 - 4.3e-15 55.1 3.0 7.4e-15 54.4 3.0 1.4 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF4423 PF14394.6 PVD33924.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) FARP PF01581.16 PVD33925.1 - 1.7e-05 24.5 35.0 2.2 9.1 0.2 8.7 9 0 0 9 9 9 5 FMRFamide related peptide family ELH PF02323.15 PVD33925.1 - 0.13 11.6 0.4 0.43 9.9 0.1 1.9 2 0 0 2 2 2 0 Egg-laying hormone precursor FARP PF01581.16 PVD33926.1 - 2.4e-18 63.1 136.5 0.16 12.6 1.4 16.4 12 3 4 16 16 16 15 FMRFamide related peptide family Ets PF00178.22 PVD33927.1 - 4.4e-14 52.7 0.8 1.2e-13 51.3 0.8 1.7 1 0 0 1 1 1 1 Ets-domain zf-C3HC4 PF00097.25 PVD33927.1 - 1.2e-07 31.5 1.3 2.9e-07 30.2 1.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD33927.1 - 1.3e-07 31.8 5.9 3.1e-07 30.6 5.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD33927.1 - 9.9e-06 25.5 4.3 2.5e-05 24.2 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD33927.1 - 2.3e-05 24.2 3.5 5.4e-05 23.0 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD33927.1 - 6.7e-05 23.1 5.2 0.00018 21.8 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PVD33927.1 - 0.00034 20.4 5.8 0.0008 19.2 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD33927.1 - 0.00062 19.7 5.6 0.0014 18.6 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain WD40 PF00400.32 PVD33927.1 - 0.00063 20.5 0.2 0.19 12.7 0.0 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-RING_11 PF17123.5 PVD33927.1 - 0.00093 18.9 0.8 0.0024 17.6 0.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PVD33927.1 - 0.001 19.2 0.4 0.001 19.2 0.4 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 PVD33927.1 - 0.0057 16.7 1.8 0.012 15.7 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PVD33927.1 - 0.0084 16.0 3.2 0.022 14.6 3.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD33927.1 - 0.018 14.8 1.5 0.047 13.5 1.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EPTP PF03736.17 PVD33927.1 - 0.56 10.3 2.5 0.66 10.0 0.0 2.4 3 0 0 3 3 3 0 EPTP domain Pkinase PF00069.25 PVD33928.1 - 2e-49 168.3 0.0 4.1e-49 167.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33928.1 - 2.6e-23 82.6 0.0 4.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD33928.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD33928.1 - 0.0095 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PVD33928.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PVD33928.1 - 0.036 13.7 0.2 2.9 7.5 0.1 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fucose_iso_N2 PF07882.12 PVD33928.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ank_5 PF13857.6 PVD33929.1 - 1.5e-19 69.8 4.5 2e-07 31.2 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD33929.1 - 2.8e-16 59.6 1.0 8e-05 23.1 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD33929.1 - 6e-13 49.2 1.8 5e-08 33.4 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD33929.1 - 2.6e-09 37.1 2.7 5.6e-06 26.6 0.3 4.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PVD33929.1 - 9.3e-06 25.6 1.6 0.0074 16.7 0.0 5.3 7 0 0 7 7 7 1 Ankyrin repeat Pkinase PF00069.25 PVD33930.1 - 3.7e-62 210.1 0.0 7.5e-62 209.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD33930.1 - 4.2e-42 144.2 0.0 9.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD33930.1 - 4.9e-05 22.8 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD33930.1 - 0.00013 20.9 0.0 0.00013 20.9 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD33930.1 - 0.026 14.5 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3782 PF12644.7 PVD33930.1 - 0.086 13.0 0.9 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Kdo PF06293.14 PVD33930.1 - 0.18 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FlxA PF14282.6 PVD33930.1 - 5.4 7.1 8.9 0.25 11.3 1.3 2.9 2 0 0 2 2 2 0 FlxA-like protein F-box-like PF12937.7 PVD33931.1 - 8.6e-15 54.4 0.6 2.6e-14 52.8 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD33931.1 - 1.5e-09 37.5 0.5 1e-08 34.8 0.1 2.7 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 PVD33931.1 - 1.7e-08 33.8 16.7 0.013 15.5 0.0 8.1 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 PVD33931.1 - 6.7e-06 26.4 3.2 0.075 13.5 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD33931.1 - 2.6 8.9 16.2 28 5.8 0.2 8.1 9 1 0 9 9 9 0 Leucine Rich Repeat SF3A2 PF16835.5 PVD33932.1 - 2.8e-08 34.0 0.9 0.00051 20.4 0.0 2.4 1 1 1 2 2 2 2 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 PVD33932.1 - 5.2e-07 29.9 2.0 5.2e-07 29.9 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type LPD24 PF18839.1 PVD33932.1 - 0.0033 17.6 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 2 Large polyvalent protein associated domain 24 Ets PF00178.22 PVD33933.1 - 2.3e-30 104.9 1.2 3.9e-30 104.2 1.2 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 PVD33933.1 - 1.2e-20 73.3 0.0 2.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SR-25 PF10500.9 PVD33933.1 - 0.098 12.3 5.4 0.2 11.3 5.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fz PF01392.22 PVD33937.1 - 2.3e-27 95.8 2.2 3.1e-27 95.4 2.2 1.2 1 0 0 1 1 1 1 Fz domain TMEM240 PF15207.6 PVD33938.1 - 0.038 13.7 0.0 0.24 11.1 0.0 2.1 3 0 0 3 3 3 0 TMEM240 family FancD2 PF14631.6 PVD33938.1 - 0.38 8.1 4.4 0.49 7.7 4.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MID_MedPIWI PF18296.1 PVD33938.1 - 0.63 9.8 5.6 1.1 8.9 5.6 1.5 1 0 0 1 1 1 0 MID domain of medPIWI GAGA_bind PF06217.12 PVD33938.1 - 7.7 6.7 15.2 0.59 10.4 9.0 1.9 1 1 1 2 2 2 0 GAGA binding protein-like family IGFBP PF00219.18 PVD33939.1 - 2.3e-08 34.6 23.2 4.3e-08 33.7 23.2 1.5 1 0 0 1 1 1 1 Insulin-like growth factor binding protein ADH_zinc_N PF00107.26 PVD33941.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD33941.1 - 9e-11 43.0 0.0 1.7e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD33941.1 - 0.00022 21.0 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.21 PVD33941.1 - 0.003 17.0 0.1 0.0081 15.5 0.2 1.7 2 0 0 2 2 2 1 ThiF family DapB_N PF01113.20 PVD33941.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2OG-FeII_Oxy_3 PF13640.6 PVD33942.1 - 2.2e-09 38.1 0.0 2.6e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1374 PF07118.11 PVD33942.1 - 0.31 11.6 3.8 0.61 10.6 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) cNMP_binding PF00027.29 PVD33943.1 - 2.7e-14 53.0 0.0 5.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Tli4_N PF18443.1 PVD33943.1 - 0.42 11.0 4.7 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Homeodomain PF00046.29 PVD33944.1 - 5.1e-24 83.9 6.8 9.2e-24 83.1 6.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD33944.1 - 0.0033 17.3 0.2 0.0033 17.3 0.2 1.8 2 0 0 2 2 2 1 Homeobox KN domain Abhydrolase_6 PF12697.7 PVD33946.1 - 4.3e-08 34.0 0.0 6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 PVD33946.1 - 1.5e-06 27.5 0.0 4.1e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 PVD33946.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_8C PF08437.10 PVD33946.1 - 0.046 13.8 0.4 0.1 12.7 0.4 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Stealth_CR2 PF11380.8 PVD33947.1 - 7.4e-47 158.0 0.2 3.5e-46 155.8 0.1 2.2 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 PVD33947.1 - 1.4e-20 72.9 0.2 6.5e-20 70.8 0.1 2.2 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 PVD33947.1 - 1.5e-18 66.4 0.4 4.3e-18 64.9 0.4 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 PVD33947.1 - 3.4e-14 53.0 35.0 8.5e-09 35.7 13.0 2.5 2 0 0 2 2 2 2 LNR domain GlcNAc-1_reg PF18440.1 PVD33947.1 - 8.4e-11 42.0 0.0 3.1e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain Stealth_CR1 PF17101.5 PVD33947.1 - 1e-10 41.1 0.0 2.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 EF-hand_5 PF13202.6 PVD33947.1 - 0.00057 19.3 0.1 0.0018 17.7 0.1 1.9 1 0 0 1 1 1 1 EF hand DMAP_binding PF06464.11 PVD33947.1 - 0.011 16.6 0.5 0.042 14.7 0.5 2.0 1 1 0 1 1 1 0 DMAP1-binding Domain EF-hand_1 PF00036.32 PVD33947.1 - 0.018 14.5 1.4 0.027 14.0 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 PVD33947.1 - 0.052 13.5 0.1 0.24 11.4 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PVD33947.1 - 0.054 14.0 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 PVD33947.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair SH3_1 PF00018.28 PVD33948.1 - 5e-13 48.4 0.1 1.1e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD33948.1 - 4e-12 45.8 0.2 8.3e-12 44.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD33948.1 - 6e-11 41.9 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain EzrA PF06160.12 PVD33948.1 - 0.0065 14.7 2.9 0.01 14.0 2.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA 2-oxogl_dehyd_N PF16078.5 PVD33948.1 - 0.1 12.2 0.1 0.32 10.6 0.1 1.8 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus LemA PF04011.12 PVD33948.1 - 0.11 12.4 1.6 0.87 9.4 1.2 2.5 1 1 0 1 1 1 0 LemA family Med30 PF11315.8 PVD33948.1 - 2.5 8.3 7.5 0.83 9.8 1.1 2.8 3 0 0 3 3 3 0 Mediator complex subunit 30 ABC2_membrane PF01061.24 PVD33949.1 - 2.3e-31 108.9 15.3 2.3e-31 108.9 15.3 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PVD33949.1 - 1.1e-28 100.4 0.0 6.2e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PVD33949.1 - 2.9e-06 27.3 0.1 0.0054 16.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PVD33949.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PVD33949.1 - 0.00023 21.6 0.0 0.00054 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 PVD33949.1 - 0.0016 18.4 0.0 0.0051 16.7 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 PVD33949.1 - 0.0017 17.9 0.0 0.0091 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD33949.1 - 0.0038 17.5 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 PVD33949.1 - 0.018 14.5 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 PVD33949.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 PVD33949.1 - 0.044 14.2 0.5 0.27 11.7 0.5 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PVD33949.1 - 0.048 13.9 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PVD33949.1 - 0.048 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 PVD33949.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 PVD33949.1 - 0.062 13.8 0.7 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD33949.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 PVD33949.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Unstab_antitox PF09720.10 PVD33949.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative addiction module component PduV-EutP PF10662.9 PVD33949.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 PVD33949.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_19 PF13245.6 PVD33949.1 - 0.18 12.1 0.0 0.62 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain UPF0542 PF15086.6 PVD33949.1 - 0.63 10.0 2.0 0.72 9.8 0.2 2.1 2 0 0 2 2 1 0 Uncharacterised protein family UPF0542 S10_plectin PF03501.15 PVD33950.1 - 6.3e-46 154.4 0.1 7.6e-46 154.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Replic_Relax PF13814.6 PVD33950.1 - 0.054 13.6 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation Glyco_hydro_47 PF01532.20 PVD33951.1 - 5.2e-98 328.9 0.0 3.6e-65 220.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Homeodomain PF00046.29 PVD33952.1 - 1.2 9.0 6.8 0.88 9.5 0.2 2.6 1 1 1 2 2 2 0 Homeodomain KIAA1430 PF13879.6 PVD33953.1 - 2e-07 31.7 1.4 4.9e-07 30.5 0.1 2.4 2 0 0 2 2 2 1 KIAA1430 homologue Kinesin PF00225.23 PVD33954.1 - 1.3e-113 379.4 0.1 1.3e-113 379.4 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD33954.1 - 6.6e-23 81.3 0.1 6.6e-23 81.3 0.1 2.7 3 0 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 PVD33954.1 - 0.18 11.9 0.1 0.18 11.9 0.1 4.1 4 1 1 5 5 5 0 Kinesin-associated DUF4298 PF14131.6 PVD33954.1 - 0.24 11.4 7.3 0.85 9.6 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) AAA_22 PF13401.6 PVD33954.1 - 3.2 8.0 6.0 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Fzo_mitofusin PF04799.13 PVD33954.1 - 5.7 6.5 9.1 2.5 7.6 0.8 2.7 2 0 0 2 2 2 0 fzo-like conserved region FliD_N PF02465.18 PVD33954.1 - 9.7 7.0 6.4 54 4.6 0.6 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus RPN1_RPN2_N PF17781.1 PVD33955.1 - 1.8e-122 408.6 0.2 4.1e-122 407.4 0.2 1.6 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 PVD33955.1 - 9.4e-26 88.9 37.0 2e-07 31.1 0.1 9.2 11 0 0 11 11 11 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 PVD33955.1 - 8.9e-20 70.5 0.3 1.8e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 PVD33955.1 - 2.1e-06 28.0 0.7 0.023 15.0 0.1 4.1 4 1 0 4 4 4 2 HEAT repeats Clathrin PF00637.20 PVD33955.1 - 0.052 13.4 0.8 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF416 PF04222.12 PVD33955.1 - 0.17 11.3 3.5 0.34 10.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) POX PF07526.11 PVD33955.1 - 2.6 8.6 7.9 16 6.0 0.1 2.6 2 0 0 2 2 2 0 Associated with HOX RLL PF10036.9 PVD33955.1 - 6.3 6.6 8.5 3.1 7.6 1.2 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein TPP_enzyme_C PF02775.21 PVD33956.1 - 3.1e-22 79.0 2.2 1.3e-21 77.0 0.2 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 PVD33956.1 - 7.4e-18 64.7 0.3 7.5e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ets PF00178.22 PVD33958.1 - 2.3e-31 108.1 0.6 3.7e-31 107.4 0.4 1.4 2 0 0 2 2 2 1 Ets-domain zf-CCCH_3 PF15663.5 PVD33959.1 - 1.8e-44 150.5 4.8 3.7e-44 149.4 4.8 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 PVD33959.1 - 0.3 11.6 21.2 1.7 9.3 2.8 3.9 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger GPHR_N PF12537.8 PVD33959.1 - 0.36 10.9 1.2 2 8.5 1.2 2.3 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PH_TFIIH PF08567.11 PVD33960.1 - 5.4e-21 74.7 0.1 1.3e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 PVD33960.1 - 2e-07 30.9 8.9 0.0018 18.2 0.3 3.4 3 0 0 3 3 3 2 BSD domain V-ATPase_H_C PF11698.8 PVD33960.1 - 0.58 10.3 3.6 3.2 7.9 0.2 3.0 3 1 0 3 3 3 0 V-ATPase subunit H Sulfate_transp PF00916.20 PVD33961.1 - 2.7e-95 319.3 19.4 3.3e-95 319.0 19.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD33961.1 - 0.00044 19.9 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PVD33961.1 - 0.001 19.4 3.6 0.001 19.4 3.6 3.3 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily Sulfatase PF00884.23 PVD33962.1 - 3.7e-22 79.1 0.7 4.2e-09 36.2 0.0 3.1 1 1 2 3 3 3 3 Sulfatase DUF4994 PF16385.5 PVD33962.1 - 5.7e-05 23.0 0.4 0.00012 21.9 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 PVD33962.1 - 0.00059 20.6 0.0 0.0012 19.6 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 PVD33962.1 - 0.003 17.8 0.3 0.024 14.9 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) adh_short PF00106.25 PVD33963.1 - 1.3e-42 145.5 0.2 1.9e-42 144.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD33963.1 - 2.1e-26 92.9 0.0 3.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD33963.1 - 2e-08 34.3 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD33963.1 - 0.048 13.1 0.6 0.48 9.8 0.6 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PVD33963.1 - 0.064 12.4 0.5 0.12 11.5 0.5 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 PVD33963.1 - 0.091 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Adenylsucc_synt PF00709.21 PVD33963.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate synthetase EGF PF00008.27 PVD33964.1 - 3.3e-31 107.2 76.3 4.1e-10 39.8 6.8 6.6 6 1 0 6 6 6 5 EGF-like domain hEGF PF12661.7 PVD33964.1 - 1e-21 76.7 69.1 2.9e-07 30.9 6.8 7.2 7 0 0 7 7 7 5 Human growth factor-like EGF DSL PF01414.19 PVD33964.1 - 7.5e-17 61.4 2.7 7.5e-17 61.4 2.7 5.0 3 2 1 5 5 5 1 Delta serrate ligand EGF_CA PF07645.15 PVD33964.1 - 1.4e-10 41.2 73.0 0.00031 20.9 6.3 6.3 5 1 1 6 6 6 4 Calcium-binding EGF domain EGF_2 PF07974.13 PVD33964.1 - 6e-08 32.9 93.2 0.0019 18.6 9.4 7.4 7 0 0 7 7 7 5 EGF-like domain EGF_3 PF12947.7 PVD33964.1 - 0.00015 21.8 5.2 0.00015 21.8 5.2 6.6 5 2 2 7 7 7 4 EGF domain FXa_inhibition PF14670.6 PVD33964.1 - 0.018 15.3 65.6 0.25 11.7 6.2 6.6 5 2 1 6 6 6 0 Coagulation Factor Xa inhibitory site Alliinase_C PF04864.13 PVD33964.1 - 0.2 10.5 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Allinase Laminin_EGF PF00053.24 PVD33964.1 - 0.29 11.3 64.3 4.9 7.4 2.3 7.2 2 2 5 7 7 7 0 Laminin EGF domain EGF PF00008.27 PVD33965.1 - 1.2e-60 201.3 127.3 2.7e-09 37.2 6.7 9.5 9 0 0 9 9 9 9 EGF-like domain hEGF PF12661.7 PVD33965.1 - 1.4e-32 111.2 113.7 1.5e-06 28.6 5.3 10.6 10 0 0 10 10 10 9 Human growth factor-like EGF EGF_2 PF07974.13 PVD33965.1 - 5.4e-19 68.3 141.3 0.0011 19.3 10.1 9.3 9 0 0 9 9 9 9 EGF-like domain EGF_3 PF12947.7 PVD33965.1 - 5.5e-06 26.5 109.3 0.055 13.7 5.1 10.5 8 2 1 9 9 9 7 EGF domain EGF_CA PF07645.15 PVD33965.1 - 2e-05 24.7 122.2 0.21 11.8 12.7 9.5 3 2 6 9 9 9 6 Calcium-binding EGF domain Laminin_EGF PF00053.24 PVD33965.1 - 0.00043 20.4 109.5 3.1 8.0 7.3 9.4 3 3 6 9 9 9 7 Laminin EGF domain OEP PF02321.18 PVD33969.1 - 0.77 9.5 4.2 1.5 8.6 0.4 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Tektin PF03148.14 PVD33970.1 - 4.5e-138 460.2 29.0 5.1e-138 460.0 29.0 1.0 1 0 0 1 1 1 1 Tektin family pPIWI_RE_REase PF18154.1 PVD33970.1 - 0.033 14.2 0.1 0.14 12.2 0.1 2.1 1 0 0 1 1 1 0 REase associating with pPIWI_RE MitMem_reg PF13012.6 PVD33970.1 - 0.069 13.6 0.4 0.069 13.6 0.4 3.1 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function PRD PF00874.20 PVD33970.1 - 0.16 12.3 2.5 5 7.5 0.2 2.8 2 0 0 2 2 2 0 PRD domain DivIC PF04977.15 PVD33970.1 - 3.7 7.4 8.6 1.5 8.7 0.6 3.5 3 0 0 3 3 3 0 Septum formation initiator Sec1 PF00995.23 PVD33971.1 - 1.6e-121 407.4 0.7 1.8e-121 407.2 0.7 1.0 1 0 0 1 1 1 1 Sec1 family RPN6_C_helix PF18503.1 PVD33971.1 - 1.7 8.5 4.0 2.1 8.1 0.6 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain LIX1 PF14954.6 PVD33972.1 - 2.9e-102 341.3 3.4 1.2e-74 250.8 2.3 2.1 1 1 1 2 2 2 2 Limb expression 1 TF_AP-2 PF03299.14 PVD33972.1 - 0.0044 17.0 0.6 0.0078 16.2 0.2 1.6 2 0 0 2 2 2 1 Transcription factor AP-2 LMWPc PF01451.21 PVD33973.1 - 1.5e-14 54.6 0.0 1.7e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Troponin PF00992.20 PVD33977.1 - 3e-34 118.2 9.0 4.3e-34 117.7 9.0 1.2 1 0 0 1 1 1 1 Troponin DUF641 PF04859.12 PVD33977.1 - 0.014 15.7 2.3 0.014 15.7 2.3 1.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF1192 PF06698.11 PVD33977.1 - 0.02 14.9 0.6 0.092 12.8 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) MPS2 PF17060.5 PVD33977.1 - 0.057 12.7 4.7 0.062 12.6 4.7 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF3510 PF12022.8 PVD33977.1 - 0.44 10.9 3.3 0.99 9.8 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) TMF_DNA_bd PF12329.8 PVD33977.1 - 1.1 9.3 10.8 0.16 12.0 4.8 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 PVD33977.1 - 1.7 8.7 9.3 0.24 11.5 3.7 2.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase adh_short PF00106.25 PVD33978.1 - 3.9e-41 140.7 0.9 5e-41 140.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD33978.1 - 4.7e-23 82.0 0.1 6.3e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD33978.1 - 2.8e-05 24.1 0.2 6e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD33978.1 - 0.001 18.6 0.1 0.0027 17.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PVD33978.1 - 0.001 19.3 0.1 0.0065 16.7 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PVD33978.1 - 0.0064 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 PVD33978.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Adenylsucc_synt PF00709.21 PVD33978.1 - 0.057 12.3 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate synthetase F420_oxidored PF03807.17 PVD33978.1 - 0.08 13.5 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 PVD33978.1 - 0.082 12.3 0.2 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 PVD33978.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AzlD PF05437.12 PVD33978.1 - 2.7 8.2 7.6 1.4 9.1 0.8 2.5 3 0 0 3 3 2 0 Branched-chain amino acid transport protein (AzlD) MAM PF00629.23 PVD33979.1 - 0 6452.4 158.0 1.7e-47 161.3 0.1 63.0 54 10 7 61 61 61 60 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33979.1 - 6.5e-24 83.9 87.5 1.4e-07 31.6 8.3 7.4 7 0 0 7 7 7 5 Low-density lipoprotein receptor domain class A CBM53 PF16760.5 PVD33979.1 - 0.064 13.9 1.2 1.5e+02 3.1 0.0 5.9 5 0 0 5 5 5 0 Starch/carbohydrate-binding module (family 53) MAM PF00629.23 PVD33980.1 - 3e-283 927.6 19.3 1.6e-41 141.9 0.0 12.4 11 2 2 13 13 13 12 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33980.1 - 2.5e-61 203.6 158.4 3.9e-09 36.6 8.2 10.6 10 0 0 10 10 10 10 Low-density lipoprotein receptor domain class A MAM PF00629.23 PVD33981.1 - 0 2030.7 34.2 3.6e-45 153.8 0.3 18.2 16 2 2 18 18 18 18 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33981.1 - 9.6e-20 70.5 58.9 2.5e-08 34.0 12.1 5.1 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A MAM PF00629.23 PVD33982.1 - 0 6110.5 135.9 1.5e-46 158.2 0.0 56.2 50 6 6 56 56 56 56 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33982.1 - 8.5e-38 128.3 86.7 4.3e-08 33.2 10.2 7.2 6 0 0 6 6 6 6 Low-density lipoprotein receptor domain class A Ribosomal_L37e PF01907.19 PVD33982.1 - 1.5 9.0 10.2 41 4.4 0.1 6.5 7 0 0 7 7 7 0 Ribosomal protein L37e MAM PF00629.23 PVD33983.1 - 9.4e-238 779.7 14.2 2.5e-42 144.5 0.0 8.1 8 0 0 8 8 8 8 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33983.1 - 1e-14 54.4 41.1 4.6e-07 29.9 7.4 4.2 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A MAM PF00629.23 PVD33984.1 - 1.6e-14 54.1 0.0 7.1e-11 42.3 0.0 2.0 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 PVD33985.1 - 1.2e-56 191.1 0.1 4.4e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33985.1 - 3.7e-20 71.8 55.4 7.8e-08 32.4 6.3 4.6 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A DUF347 PF03988.12 PVD33985.1 - 0.1 12.8 0.1 25 5.2 0.0 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) MAM PF00629.23 PVD33986.1 - 0 3973.3 81.4 3.4e-42 144.1 0.1 40.2 37 3 3 40 40 40 40 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33986.1 - 8e-94 307.6 278.8 3.1e-08 33.7 8.6 17.9 17 0 0 17 17 17 17 Low-density lipoprotein receptor domain class A RT_RNaseH_2 PF17919.1 PVD33987.1 - 1.1e-33 115.2 0.1 3e-33 113.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PVD33987.1 - 8.2e-30 103.2 0.2 2.4e-29 101.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 PVD33987.1 - 2.2e-23 82.7 0.0 5e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 PVD33987.1 - 1.6e-22 79.4 0.1 3e-21 75.3 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 PVD33987.1 - 1.1e-07 31.5 0.0 3.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 PVD33987.1 - 0.0091 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger MAM PF00629.23 PVD33988.1 - 0 4694.9 98.7 1.9e-46 157.9 0.2 43.6 42 2 1 43 43 43 43 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33988.1 - 2.4e-91 299.6 282.1 4.5e-08 33.2 9.1 17.9 17 0 0 17 17 17 16 Low-density lipoprotein receptor domain class A MAM PF00629.23 PVD33989.1 - 0 1845.7 39.4 5.1e-46 156.5 0.2 19.1 17 3 2 19 19 19 18 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33989.1 - 1e-17 64.0 34.3 3.1e-08 33.7 10.1 4.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A EGF PF00008.27 PVD33989.1 - 3.2 8.2 17.7 0.083 13.2 8.4 3.2 2 0 0 2 2 2 0 EGF-like domain MAM PF00629.23 PVD33990.1 - 0 2001.0 49.4 1.5e-44 151.7 0.6 19.8 19 1 1 20 20 20 19 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33990.1 - 1.5e-23 82.7 42.5 9.3e-09 35.4 6.8 4.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DUF2990 PF11693.8 PVD33990.1 - 0.028 14.6 0.6 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) PKD PF00801.20 PVD33990.1 - 0.2 11.5 16.3 0.16 11.8 0.2 5.1 4 0 0 4 4 4 0 PKD domain MAM PF00629.23 PVD33991.1 - 0 1547.5 41.2 9.8e-42 142.6 0.0 19.9 17 3 3 20 20 20 18 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 PVD33991.1 - 1.6e-70 233.0 185.7 3.9e-08 33.4 9.0 11.9 11 0 0 11 11 11 11 Low-density lipoprotein receptor domain class A C2 PF00168.30 PVD33993.1 - 3.1e-15 56.3 0.0 5.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Phospho_p8 PF10195.9 PVD33994.1 - 0.11 13.0 0.3 0.18 12.3 0.3 1.3 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Phospho_p8 PF10195.9 PVD33995.1 - 9.5e-18 64.5 7.9 9.5e-18 64.5 7.9 2.7 3 0 0 3 3 3 1 DNA-binding nuclear phosphoprotein p8 zf-CCCH_2 PF14608.6 PVD33995.1 - 7.5e-06 26.2 24.7 0.00011 22.6 2.9 3.5 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger PWI PF01480.17 PVD33995.1 - 0.0003 21.0 0.2 0.00098 19.4 0.1 2.0 2 0 0 2 2 2 1 PWI domain zf-CCCH_4 PF18044.1 PVD33995.1 - 0.004 16.9 3.4 0.004 16.9 3.4 2.8 2 1 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD33995.1 - 0.054 13.6 0.3 0.054 13.6 0.3 3.9 5 0 0 5 5 5 0 Zinc finger domain C1ORF64 PF15547.6 PVD33995.1 - 0.27 11.7 3.6 0.55 10.7 1.2 2.7 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein zf-CCCH PF00642.24 PVD33995.1 - 1.9 8.5 15.7 0.34 10.9 1.3 3.0 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TRAUB PF08164.12 PVD33996.1 - 1.7e-31 108.5 1.0 1.7e-31 108.5 1.0 3.2 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 PVD33996.1 - 2.7e-27 96.1 0.1 2.7e-27 96.1 0.1 3.4 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF3263 PF11662.8 PVD33996.1 - 0.0075 16.1 0.1 0.027 14.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) RhoGAP PF00620.27 PVD33997.1 - 1.3e-30 106.3 0.0 2.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 PVD33997.1 - 0.00032 21.2 0.1 0.00088 19.7 0.1 1.7 1 0 0 1 1 1 1 MyTH4 domain PAPA-1 PF04795.12 PVD34000.1 - 0.083 13.7 14.0 0.63 10.9 1.5 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region DUF2052 PF09747.9 PVD34000.1 - 0.12 12.5 11.7 0.13 12.4 11.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PI3K_1B_p101 PF10486.9 PVD34000.1 - 0.17 9.7 4.6 0.17 9.6 4.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 PVD34000.1 - 2.6 6.3 10.8 2.5 6.3 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CLTH PF10607.9 PVD34005.1 - 1.3e-32 112.7 1.8 2e-32 112.2 1.8 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PVD34005.1 - 6e-10 38.7 0.7 2.1e-09 37.0 0.3 2.1 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 PVD34005.1 - 0.0066 16.8 0.3 0.018 15.4 0.1 1.8 1 1 1 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus Nup35_RRM PF05172.13 PVD34006.1 - 2.2e-23 82.1 0.0 4.4e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 PVD34006.1 - 4.5e-10 39.4 0.0 7.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 PVD34006.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4504 PF14953.6 PVD34007.1 - 7.9e-26 91.0 0.7 1.6e-25 90.0 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Zip PF02535.22 PVD34008.1 - 3.1e-63 214.0 6.2 4.7e-63 213.4 6.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter ZIP4_domain PF18292.1 PVD34008.1 - 0.0027 17.6 0.3 0.006 16.5 0.2 1.6 1 1 0 1 1 1 1 Zinc transporter ZIP4 domain DUF3924 PF13062.6 PVD34008.1 - 0.037 14.0 0.1 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) SelP_N PF04592.14 PVD34008.1 - 0.65 9.4 8.6 1.1 8.7 8.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_2 PF12796.7 PVD34009.1 - 2e-49 166.1 14.4 5.8e-16 58.9 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34009.1 - 6.4e-39 131.8 12.1 7.9e-11 42.3 1.0 5.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34009.1 - 3.4e-37 126.0 26.8 1.3e-07 31.8 0.1 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34009.1 - 4.8e-34 112.5 7.9 0.00024 21.3 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 PVD34009.1 - 2.1e-25 88.0 20.9 0.012 16.0 0.1 8.4 7 1 1 8 8 8 8 Ankyrin repeat PLAT PF01477.23 PVD34010.1 - 6.5e-140 458.8 25.9 4.1e-23 82.2 0.8 9.2 9 0 0 9 9 9 9 PLAT/LH2 domain MG4 PF17789.1 PVD34010.1 - 0.096 12.8 0.0 33 4.7 0.0 3.1 2 0 0 2 2 2 0 Macroglobulin domain MG4 DUF4880 PF16220.5 PVD34010.1 - 0.66 9.9 2.5 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) PLAT PF01477.23 PVD34011.1 - 5.3e-159 520.4 22.2 2e-22 80.0 0.1 8.3 8 0 0 8 8 8 8 PLAT/LH2 domain ATS3 PF06232.11 PVD34011.1 - 1.3e-17 63.9 0.0 0.12 12.3 0.0 7.5 8 0 0 8 8 8 5 Embryo-specific protein 3, (ATS3) DUF4493 PF14900.6 PVD34011.1 - 0.88 9.4 4.9 54 3.6 0.0 4.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4493) zf-C4 PF00105.18 PVD34012.1 - 9.9e-33 112.4 14.7 1.8e-32 111.6 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD34012.1 - 6e-23 81.5 0.6 1.1e-22 80.7 0.6 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MTP18 PF10558.9 PVD34012.1 - 0.19 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) PL48 PF15903.5 PVD34013.1 - 2.5e-74 250.4 0.9 3.1e-73 246.7 0.1 2.3 2 1 0 2 2 2 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 PVD34013.1 - 1.6e-06 28.4 0.6 9.1e-06 26.0 0.4 2.2 1 1 1 2 2 2 1 HEAT repeats LRV PF01816.17 PVD34014.1 - 0.28 11.7 2.4 0.47 11.0 0.4 2.5 2 0 0 2 2 2 0 Leucine rich repeat variant WSS_VP PF12175.8 PVD34016.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Glyco_tranf_2_3 PF13641.6 PVD34017.1 - 0.001 19.0 0.2 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 BatA PF07584.11 PVD34017.1 - 0.0051 17.1 0.5 0.01 16.2 0.1 1.7 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal OMPdecase PF00215.24 PVD34018.1 - 8.8e-77 257.7 0.0 1.3e-76 257.1 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 PVD34018.1 - 6e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4448 PF14610.6 PVD34019.1 - 0.0076 16.1 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF973 PF06157.11 PVD34019.1 - 0.35 9.9 0.0 0.52 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) ketoacyl-synt PF00109.26 PVD34020.1 - 6e-83 278.3 0.1 2e-82 276.6 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PVD34020.1 - 3.1e-49 167.3 0.1 8.1e-49 166.0 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 PVD34020.1 - 6.3e-46 157.3 0.0 1.2e-45 156.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 PVD34020.1 - 1.7e-33 115.1 0.0 4.3e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 PVD34020.1 - 2.9e-31 108.8 0.0 4.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 PVD34020.1 - 5.3e-17 62.3 0.1 1.7e-15 57.4 0.0 3.3 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 PVD34020.1 - 4.2e-11 43.0 0.0 2e-10 40.9 0.0 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD34020.1 - 9.4e-09 35.0 0.1 3.5e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD34020.1 - 9.6e-07 28.6 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Condensation PF00668.20 PVD34020.1 - 1.4e-06 27.3 0.0 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Thiolase_N PF00108.23 PVD34020.1 - 3.4e-06 26.6 0.1 7.3e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lectin_C PF00059.21 PVD34021.1 - 1e-12 48.7 0.6 2.3e-12 47.6 0.0 1.8 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.12 PVD34021.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.6 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like TIC20 PF16166.5 PVD34021.1 - 0.071 12.9 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Utp14 PF04615.13 PVD34022.1 - 0.072 11.7 0.5 0.079 11.5 0.5 1.0 1 0 0 1 1 1 0 Utp14 protein HSP20 PF00011.21 PVD34023.1 - 1.3e-31 108.7 5.3 3.6e-17 62.4 0.1 2.8 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD34023.1 - 4.9e-08 32.4 0.2 0.0024 17.4 0.0 2.5 2 0 0 2 2 2 2 HSP20-like domain found in ArsA YabP PF07873.11 PVD34023.1 - 0.0014 18.4 1.1 0.48 10.3 0.0 3.6 4 0 0 4 4 4 1 YabP family NusG_add PF18298.1 PVD34023.1 - 0.091 13.0 3.1 2.8 8.2 0.3 2.5 2 0 0 2 2 2 0 NusG additional domain EVE PF01878.18 PVD34024.1 - 7.5e-49 165.5 0.8 2.7e-48 163.7 0.1 1.8 2 0 0 2 2 2 1 EVE domain LRR_4 PF12799.7 PVD34025.1 - 7e-08 32.7 12.5 1.1e-05 25.7 0.7 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD34025.1 - 1.8e-06 27.6 0.1 3.6e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD34025.1 - 1.7e-05 24.5 6.7 0.0057 16.4 1.0 3.4 2 1 0 2 2 2 2 Leucine rich repeat PAF PF15715.5 PVD34025.1 - 0.33 11.5 0.0 0.33 11.5 0.0 3.3 4 0 0 4 4 4 0 PCNA-associated factor histone like domain LRR_1 PF00560.33 PVD34025.1 - 0.93 10.3 7.8 42 5.2 0.9 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat DUF1068 PF06364.12 PVD34027.1 - 0.086 12.7 0.6 0.23 11.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF3278 PF11683.8 PVD34027.1 - 0.26 11.4 1.2 1.5 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) TP2 PF01254.18 PVD34027.1 - 3.8 8.1 9.7 0.77 10.4 6.2 1.6 2 0 0 2 2 2 0 Nuclear transition protein 2 HLH PF00010.26 PVD34028.1 - 0.00053 19.9 0.5 0.0015 18.5 0.3 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain INO80_Ies4 PF08193.11 PVD34028.1 - 0.0013 18.8 0.8 0.0029 17.7 0.8 1.5 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Methyltransf_25 PF13649.6 PVD34029.1 - 1.8e-08 34.9 0.0 3.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PVD34029.1 - 7.8e-08 32.1 0.0 9.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 PVD34029.1 - 1.2e-06 29.0 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD34029.1 - 1.1e-05 25.3 0.1 2.2e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD34029.1 - 3.2e-05 23.8 0.0 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD34029.1 - 0.00018 20.5 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 PVD34029.1 - 0.00019 20.8 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PVD34029.1 - 0.00057 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 PVD34029.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 PVD34029.1 - 0.0012 18.7 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 PVD34029.1 - 0.0061 16.3 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 PVD34029.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 PVD34029.1 - 0.057 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GidB PF02527.15 PVD34029.1 - 0.059 12.7 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Tetraspanin PF00335.20 PVD34030.1 - 5.9e-54 183.2 11.6 7.6e-54 182.8 11.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2431 PF10354.9 PVD34031.1 - 3.5e-40 138.0 0.0 6.8e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 PVD34031.1 - 2.5e-09 37.4 0.0 6.6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain QIL1 PF15884.5 PVD34034.1 - 1.3e-15 57.8 0.7 1.7e-15 57.4 0.7 1.2 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 Clc-like PF07062.12 PVD34036.1 - 2.1e-06 27.4 4.2 3.1e-06 26.8 0.1 2.4 2 1 0 2 2 2 1 Clc-like PMP22_Claudin PF00822.20 PVD34036.1 - 0.003 17.4 1.3 0.44 10.4 0.1 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD34036.1 - 0.015 15.2 1.4 0.59 10.0 0.2 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Claudin_2 PF13903.6 PVD34036.1 - 0.048 13.4 3.5 2.4 7.8 0.0 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 PVD34036.1 - 0.36 11.0 3.6 0.44 10.7 1.4 2.2 2 1 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein SLATT_1 PF18181.1 PVD34036.1 - 3 7.8 4.8 3.9 7.4 0.0 2.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2892 PF11127.8 PVD34036.1 - 5 7.2 11.3 0.83 9.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) CBM_14 PF01607.24 PVD34038.1 - 2.7e-13 49.9 8.9 3.2e-07 30.4 0.3 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain RANK_CRD_2 PF18278.1 PVD34038.1 - 0.54 10.5 4.5 2.7 8.2 0.1 3.0 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Tropomyosin PF00261.20 PVD34039.1 - 0.23 10.8 0.2 13 5.1 0.1 2.4 1 1 0 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.7 PVD34039.1 - 0.38 10.9 4.4 12 6.1 0.2 2.6 1 1 3 4 4 4 0 Tropomyosin like VWA PF00092.28 PVD34040.1 - 9.2e-14 52.1 0.1 1.4e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD34040.1 - 4.3e-10 40.2 0.2 7.7e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PVD34040.1 - 0.022 14.7 0.6 0.034 14.1 0.6 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Hydrolase_6 PF13344.6 PVD34041.1 - 1.2e-30 105.6 0.0 2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD34041.1 - 8.8e-18 64.1 0.0 2.5e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 PVD34041.1 - 2.6e-12 47.5 0.0 2.1e-11 44.5 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PVD34041.1 - 2.6e-07 30.9 0.1 0.00014 22.0 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 PVD34041.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 PVD34041.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4471 PF14740.6 PVD34043.1 - 2e-24 86.4 0.1 3.9e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 PVD34043.1 - 1.3e-17 63.7 0.0 3.5e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) RskA PF10099.9 PVD34043.1 - 1.5 9.1 10.2 24 5.1 0.1 3.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Spc24 PF08286.11 PVD34043.1 - 5.9 7.2 9.6 2.1 8.6 1.0 3.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 PVD34043.1 - 8.8 5.8 17.5 1.7 8.2 5.6 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fibrinogen_C PF00147.18 PVD34047.1 - 1.1e-71 241.2 7.2 4.7e-71 239.1 7.5 1.8 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain FCH PF00611.23 PVD34047.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2897 PF11446.8 PVD34047.1 - 3 7.8 3.7 5.7 6.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) HNOBA PF07701.14 PVD34048.1 - 6.7e-59 199.0 0.0 9.4e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 PVD34048.1 - 8e-55 185.3 0.3 1.2e-54 184.7 0.3 1.3 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 PVD34048.1 - 8.2e-43 146.2 0.4 1.5e-42 145.3 0.4 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain BTB PF00651.31 PVD34049.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Yip1 PF04893.17 PVD34050.1 - 4.5e-08 33.0 8.8 6.4e-08 32.5 8.8 1.3 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 PVD34050.1 - 0.00095 18.7 10.6 0.0073 15.8 10.6 2.0 1 1 0 1 1 1 1 YIF1 DUF2339 PF10101.9 PVD34050.1 - 0.0055 15.3 7.0 0.0073 14.9 7.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF4989 PF16379.5 PVD34050.1 - 0.031 13.6 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) DUF4199 PF13858.6 PVD34050.1 - 0.046 14.1 0.5 0.046 14.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4131 PF13567.6 PVD34050.1 - 0.2 11.3 4.0 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4271 PF14093.6 PVD34050.1 - 0.57 10.1 16.6 0.11 12.4 12.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) ABC2_membrane_3 PF12698.7 PVD34050.1 - 6.2 5.8 20.9 5.4 6.0 15.0 2.5 2 1 1 3 3 3 0 ABC-2 family transporter protein RhoGAP PF00620.27 PVD34051.1 - 2.4e-45 154.1 1.0 1.3e-43 148.5 0.0 3.3 2 1 1 3 3 3 1 RhoGAP domain RhoGAP-FF1 PF16512.5 PVD34051.1 - 3.2e-18 66.2 5.3 9.8e-17 61.4 0.4 3.7 2 1 1 3 3 3 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 PVD34051.1 - 1.1e-12 47.9 0.0 3.3e-06 26.8 0.1 3.4 3 0 0 3 3 3 3 Ras family FF PF01846.19 PVD34051.1 - 4.4e-08 33.2 0.4 0.11 12.7 1.0 4.0 3 0 0 3 3 3 3 FF domain Roc PF08477.13 PVD34051.1 - 0.12 12.6 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD34051.1 - 0.15 12.0 0.2 15 5.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Rap1-DNA-bind PF09197.10 PVD34051.1 - 2.5 8.7 7.8 40 4.9 0.1 3.8 3 0 0 3 3 3 0 Rap1, DNA-binding rRNA_processing PF08524.11 PVD34051.1 - 7.9 6.5 16.7 5.4 7.0 12.5 2.5 2 0 0 2 2 2 0 rRNA processing Ephrin PF00812.17 PVD34052.1 - 2.4e-36 124.8 1.5 3.4e-36 124.3 1.5 1.2 1 0 0 1 1 1 1 Ephrin zf-C2H2_4 PF13894.6 PVD34053.1 - 1.9 9.6 9.7 1 10.4 1.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_10 PF00852.19 PVD34054.1 - 3.4e-63 212.6 0.4 3.4e-63 212.6 0.4 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD34054.1 - 6e-21 75.0 0.9 7.5e-20 71.5 0.2 2.4 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Hormone_3 PF00159.18 PVD34054.1 - 0.21 11.7 0.9 30 4.8 0.1 2.8 2 0 0 2 2 2 0 Pancreatic hormone peptide Viral_alk_exo PF01771.17 PVD34055.1 - 9.8e-08 31.3 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Viral alkaline exonuclease YqaJ PF09588.10 PVD34055.1 - 7.3e-06 26.2 0.1 1.1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain DUF1525 PF07511.11 PVD34055.1 - 0.018 15.2 0.3 0.031 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Ank_2 PF12796.7 PVD34056.1 - 2.6e-42 143.3 7.2 4.5e-10 40.0 0.2 6.2 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34056.1 - 1.2e-40 137.4 10.6 3.4e-08 33.9 0.8 8.9 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34056.1 - 1.2e-33 114.7 11.1 2.6e-09 37.1 0.1 7.8 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD34056.1 - 9.9e-26 89.0 18.3 6.4e-06 26.4 0.4 10.2 10 0 0 10 10 10 4 Ankyrin repeat Ank_3 PF13606.6 PVD34056.1 - 8.6e-25 84.1 16.4 4.6e-07 29.6 0.1 11.1 10 1 0 10 10 10 4 Ankyrin repeat CH PF00307.31 PVD34056.1 - 7.2e-08 32.6 2.7 0.00069 19.8 0.1 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF4485 PF14846.6 PVD34056.1 - 0.037 14.1 0.8 0.11 12.5 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) MerR-DNA-bind PF09278.11 PVD34056.1 - 0.045 14.3 0.8 0.2 12.2 0.8 2.2 1 1 0 1 1 1 0 MerR, DNA binding DUF3037 PF11236.8 PVD34056.1 - 0.092 13.2 0.5 0.23 11.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) TPR_MLP1_2 PF07926.12 PVD34056.1 - 0.13 12.3 0.8 0.27 11.3 0.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein API5 PF05918.11 PVD34057.1 - 2.8e-192 640.2 0.0 3.4e-192 639.9 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Adaptin_N PF01602.20 PVD34057.1 - 0.00013 20.7 0.4 0.00019 20.1 0.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PVD34057.1 - 0.0032 17.5 2.4 0.019 15.0 1.7 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD34057.1 - 0.029 14.8 0.1 0.68 10.4 0.0 2.8 1 1 1 2 2 2 0 HEAT repeats FANCI_S2 PF14676.6 PVD34057.1 - 0.038 14.3 1.5 0.78 10.0 0.0 3.3 4 1 0 4 4 4 0 FANCI solenoid 2 MMS19_N PF14500.6 PVD34057.1 - 0.042 13.4 6.7 0.25 10.9 4.4 2.9 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 PVD34057.1 - 0.24 11.6 1.8 18 5.6 0.4 2.6 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 PVD34057.1 - 0.42 11.1 2.6 3 8.3 0.2 3.1 3 1 0 3 3 3 0 Telomere length regulation protein RHINO PF15319.6 PVD34058.1 - 2.5e-10 40.8 11.7 2.5e-10 40.8 11.7 2.3 2 0 0 2 2 2 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein RIFIN PF02009.16 PVD34058.1 - 9.8e-05 22.4 1.5 0.00022 21.2 1.5 1.6 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 PVD34058.1 - 0.0041 17.0 0.8 0.0041 17.0 0.8 2.3 2 0 0 2 2 2 1 TMEM154 protein family Sod_Fe_C PF02777.18 PVD34058.1 - 0.09 13.0 0.2 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain CTV_P6 PF06706.11 PVD34058.1 - 0.17 11.6 0.2 0.38 10.5 0.2 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein polyprenyl_synt PF00348.17 PVD34059.1 - 1.5e-94 315.9 0.0 1.8e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CUB PF00431.20 PVD34060.1 - 5.7e-08 33.1 0.0 9.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 PVD34060.1 - 0.013 15.7 1.3 0.027 14.7 1.3 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD34061.1 - 1.7e-10 41.0 16.1 1.7e-06 28.1 1.2 4.9 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD34061.1 - 3.4e-05 24.5 0.0 6.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain PixA PF12306.8 PVD34061.1 - 0.044 14.0 0.5 0.08 13.1 0.5 1.3 1 0 0 1 1 1 0 Inclusion body protein Ldl_recept_a PF00057.18 PVD34062.1 - 1.6e-06 28.2 13.1 0.0046 17.1 4.5 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 PVD34063.1 - 0.0094 16.7 0.0 0.039 14.7 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain DUF4131 PF13567.6 PVD34065.1 - 2.3 7.8 5.0 15 5.2 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 7tm_1 PF00001.21 PVD34066.1 - 6.9e-14 51.8 17.1 1.4e-13 50.8 17.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ldl_recept_a PF00057.18 PVD34066.1 - 3.7e-09 36.7 31.2 4.9e-06 26.7 1.2 5.0 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD34066.1 - 2.2e-07 30.5 6.4 1.6e-05 24.6 1.6 2.6 2 0 0 2 2 2 2 Leucine rich repeat 7TM_GPCR_Srx PF10328.9 PVD34066.1 - 3.9e-06 26.7 11.7 6.7e-06 25.9 11.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRR_4 PF12799.7 PVD34066.1 - 2e-05 24.9 8.1 0.023 15.1 0.8 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD34066.1 - 0.0002 21.5 5.2 0.2 12.3 0.1 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD34066.1 - 0.00084 18.9 0.7 0.002 17.6 0.7 1.6 1 1 0 1 1 1 1 Leucine-rich repeat 7TM_GPCR_Srsx PF10320.9 PVD34066.1 - 0.071 12.5 14.1 0.11 11.9 14.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_6 PF13516.6 PVD34066.1 - 0.14 12.3 3.0 40 4.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF2207 PF09972.9 PVD34066.1 - 0.3 9.8 0.7 0.5 9.1 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.27 PVD34067.1 - 8.8e-39 133.3 0.1 1.2e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_2 PF08356.12 PVD34067.1 - 0.0044 17.0 0.1 0.0095 15.9 0.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 PVD34070.1 - 3.5e-32 111.3 0.0 4.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD34070.1 - 2.7e-07 30.8 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PVD34070.1 - 2.4e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD34070.1 - 0.00018 21.5 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 PVD34070.1 - 0.00034 20.1 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 PVD34070.1 - 0.03 14.3 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FARP PF01581.16 PVD34071.1 - 0.31 11.7 19.8 3.5e+02 2.6 0.0 9.2 8 1 2 10 10 10 0 FMRFamide related peptide family WYL_3 PF18488.1 PVD34073.1 - 0.066 13.6 0.3 0.75 10.2 0.1 2.2 2 0 0 2 2 2 0 WYL domain Prenylcys_lyase PF07156.14 PVD34075.1 - 2.8e-115 385.3 4.8 3.3e-115 385.1 4.8 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase G8 PF10162.9 PVD34076.1 - 9.8e-27 93.5 0.0 3.9e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 G8 domain WSC PF01822.19 PVD34076.1 - 5.6e-12 45.7 2.8 2.8e-11 43.4 3.1 2.2 2 0 0 2 2 2 1 WSC domain Lectin_C PF00059.21 PVD34076.1 - 3e-10 40.8 13.8 1.4e-06 28.9 0.1 5.2 7 0 0 7 7 7 2 Lectin C-type domain ILEI PF15711.5 PVD34076.1 - 2.8e-05 24.5 0.0 8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Interleukin-like EMT inducer Beta_helix PF13229.6 PVD34076.1 - 0.00025 20.9 0.8 0.00093 19.1 0.8 1.8 1 1 0 1 1 1 1 Right handed beta helix region UL45 PF05473.12 PVD34076.1 - 0.0025 17.5 0.1 1.1 8.8 0.0 2.7 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like GFO_IDH_MocA PF01408.22 PVD34077.1 - 6.7e-25 88.2 0.0 1.1e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 PVD34077.1 - 0.02 15.4 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 PVD34077.1 - 0.036 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 PVD34077.1 - 0.094 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Gal-bind_lectin PF00337.22 PVD34078.1 - 0.0001 21.8 10.0 0.08 12.5 0.7 4.9 5 0 0 5 5 5 2 Galactoside-binding lectin Rho_GDI PF02115.17 PVD34078.1 - 0.003 17.3 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 2 RHO protein GDP dissociation inhibitor Pik1 PF11522.8 PVD34078.1 - 0.097 12.6 0.8 18 5.4 0.2 2.9 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Nodulin_late PF07127.11 PVD34078.1 - 3.1 8.2 11.5 2.9 8.3 2.2 3.0 2 0 0 2 2 2 0 Late nodulin protein VWA PF00092.28 PVD34079.1 - 4.5e-09 36.8 0.0 1.6e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PVD34079.1 - 0.0019 18.8 0.0 0.008 16.8 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 PVD34080.1 - 2e-10 40.7 0.5 2e-10 40.7 0.5 1.8 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Mito_carr PF00153.27 PVD34081.1 - 7.1e-72 237.4 0.7 7.7e-26 89.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PVD34081.1 - 0.0033 16.6 0.6 3.7 6.6 0.0 3.4 4 0 0 4 4 4 2 Gammaproteobacterial serine protease Rieske PF00355.26 PVD34082.1 - 7.1e-11 41.9 0.1 1e-10 41.4 0.1 1.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PVD34082.1 - 1.7e-10 40.8 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain QVR PF17064.5 PVD34083.1 - 9.4e-06 25.8 7.6 2.9e-05 24.2 7.6 1.9 1 0 0 1 1 1 1 Sleepless protein LIM PF00412.22 PVD34086.1 - 2.9e-25 88.2 24.6 5.5e-13 48.9 8.3 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 PVD34086.1 - 1.4e-06 27.7 15.7 0.6 9.7 0.1 4.7 4 0 0 4 4 4 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD34086.1 - 0.0026 17.8 26.5 0.94 9.6 0.3 4.2 4 0 0 4 4 4 3 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 PVD34086.1 - 0.012 15.6 2.3 1.7 8.8 0.4 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ACC PF17848.1 PVD34086.1 - 0.027 14.5 3.6 0.28 11.3 0.3 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 PVD34086.1 - 0.036 13.8 29.8 0.49 10.2 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-Mss51 PF13824.6 PVD34086.1 - 0.044 13.9 1.6 0.044 13.9 1.6 3.4 2 2 1 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 PVD34086.1 - 0.21 11.7 26.3 5.5 7.1 8.9 4.3 2 2 0 2 2 2 0 Double zinc ribbon SelR PF01641.18 PVD34086.1 - 0.23 11.5 9.3 1.1 9.4 1.1 2.2 2 0 0 2 2 2 0 SelR domain zf-ribbon_3 PF13248.6 PVD34086.1 - 0.47 9.9 0.1 0.47 9.9 0.1 5.1 6 0 0 6 6 6 0 zinc-ribbon domain MqsA_antitoxin PF15731.5 PVD34086.1 - 1.4 9.0 6.7 12 6.1 0.1 3.0 2 2 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-CCHC_5 PF14787.6 PVD34086.1 - 1.5 8.6 0.1 1.5 8.6 0.1 3.3 3 0 0 3 3 2 0 GAG-polyprotein viral zinc-finger TF_Zn_Ribbon PF08271.12 PVD34086.1 - 2 8.0 23.6 0.78 9.3 0.3 4.7 4 1 0 4 4 4 0 TFIIB zinc-binding PSCyt3 PF07627.11 PVD34086.1 - 3.8 7.9 12.2 15 5.9 2.0 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1588) DUF2616 PF11077.8 PVD34086.1 - 4.5 6.9 10.3 4.5 7.0 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) DUF2688 PF10892.8 PVD34086.1 - 4.9 6.7 10.3 11 5.5 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2688) NinD PF17466.2 PVD34086.1 - 6.9 6.8 10.6 14 5.9 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function Ank_4 PF13637.6 PVD34087.1 - 8.5e-35 118.7 18.5 1.1e-09 38.6 0.1 6.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD34087.1 - 1.1e-33 115.6 0.1 5e-13 49.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 PVD34087.1 - 1.2e-33 116.0 13.0 1.2e-33 116.0 13.0 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.6 PVD34087.1 - 4.3e-31 103.5 2.9 9.8e-07 28.6 0.2 7.9 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 PVD34087.1 - 3e-27 93.8 2.7 2.5e-07 30.9 1.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PVD34087.1 - 8.5e-26 89.7 5.2 6.5e-07 29.5 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) A_deamin PF02137.18 PVD34090.1 - 3.4e-106 355.4 0.0 4.7e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 PVD34090.1 - 1.2e-08 35.5 0.0 3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF1376 PF07120.11 PVD34090.1 - 0.11 12.9 0.1 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) HTH_24 PF13412.6 PVD34092.1 - 1.7e-06 27.5 0.2 5.2e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding z-alpha PF02295.17 PVD34092.1 - 3.1e-05 23.9 0.2 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain TrmB PF01978.19 PVD34092.1 - 8.5e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 PVD34092.1 - 9.3e-05 22.2 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 PVD34092.1 - 0.0001 22.7 0.1 0.00039 20.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain TFIIE_beta PF02186.15 PVD34092.1 - 0.00013 22.1 0.6 0.062 13.6 0.0 2.3 2 0 0 2 2 2 2 TFIIE beta subunit core domain HTH_5 PF01022.20 PVD34092.1 - 0.00075 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_micro PF17007.5 PVD34092.1 - 0.00091 18.2 0.2 0.001 18.0 0.2 1.0 1 0 0 1 1 1 1 HTH-like LexA_DNA_bind PF01726.16 PVD34092.1 - 0.0012 18.5 1.7 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 LexA DNA binding domain HTH_20 PF12840.7 PVD34092.1 - 0.0015 18.6 0.0 0.0039 17.2 0.0 1.7 3 0 0 3 3 2 1 Helix-turn-helix domain B-block_TFIIIC PF04182.12 PVD34092.1 - 0.0024 18.0 0.2 0.0033 17.5 0.2 1.4 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC Sulfolobus_pRN PF05584.11 PVD34092.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein HTH_11 PF08279.12 PVD34092.1 - 0.04 13.8 1.0 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 HTH domain HTH_IclR PF09339.10 PVD34092.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.20 PVD34092.1 - 0.046 14.1 0.3 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator HTH_34 PF13601.6 PVD34092.1 - 0.051 13.8 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 PVD34092.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain BLACT_WH PF17778.1 PVD34092.1 - 0.1 12.6 0.4 0.1 12.6 0.4 1.8 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain WD40 PF00400.32 PVD34093.1 - 0.82 10.6 9.5 7.3 7.7 0.4 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Ysc84 PF04366.12 PVD34094.1 - 2.6e-39 133.9 0.0 2.6e-39 133.9 0.0 3.9 3 1 0 3 3 3 1 Las17-binding protein actin regulator Nsp1_C PF05064.13 PVD34094.1 - 2.8e-29 101.3 6.7 6.3e-29 100.1 6.7 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region SH3_1 PF00018.28 PVD34094.1 - 3.1e-10 39.5 0.0 8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD34094.1 - 4.7e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD34094.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain 7TMR-HDED PF07697.11 PVD34094.1 - 0.072 13.2 3.2 0.17 12.0 3.2 1.6 1 1 0 1 1 1 0 7TM-HD extracellular Nucleoporin_FG2 PF15967.5 PVD34094.1 - 1.1 7.8 188.6 0.0092 14.6 74.4 6.3 2 1 4 6 6 6 0 Nucleoporin FG repeated region Tetraspanin PF00335.20 PVD34096.1 - 4.3e-31 108.4 4.7 6.3e-31 107.9 4.7 1.3 1 0 0 1 1 1 1 Tetraspanin family GTP-bdg_M PF16360.5 PVD34096.1 - 5.6e-17 62.1 4.0 1.2e-16 61.0 4.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 PVD34096.1 - 6.1e-16 58.5 0.3 1.6e-15 57.1 0.2 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 PVD34096.1 - 2.2e-09 37.9 0.4 1e-08 35.7 0.0 2.4 3 0 0 3 3 2 1 GTP-binding GTPase N-terminal CD20 PF04103.15 PVD34096.1 - 0.00059 20.0 7.0 0.00079 19.5 2.7 2.3 2 0 0 2 2 2 1 CD20-like family TniB PF05621.11 PVD34096.1 - 0.0044 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 PVD34096.1 - 0.0077 15.8 3.4 0.17 11.5 0.4 2.4 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 PVD34096.1 - 0.026 14.6 0.1 0.076 13.1 0.0 1.8 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 PVD34096.1 - 0.032 13.8 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD34096.1 - 0.042 13.4 1.2 0.31 10.6 1.5 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PVD34096.1 - 0.05 14.1 0.4 0.21 12.1 0.1 2.1 1 1 1 2 2 2 0 ABC transporter AAA_16 PF13191.6 PVD34096.1 - 0.062 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 PVD34096.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RPAP3_C PF13877.6 PVD34096.1 - 0.1 13.2 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 LtrA PF06772.11 PVD34096.1 - 1 8.5 9.2 2.1 7.5 9.2 1.4 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF543 PF04418.12 PVD34096.1 - 1.7 8.6 4.4 0.45 10.5 0.5 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF543) GFO_IDH_MocA PF01408.22 PVD34097.1 - 1.3e-07 32.5 0.0 2.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD34097.1 - 0.0034 17.4 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ANF_receptor PF01094.28 PVD34098.1 - 2.8e-34 118.8 0.0 3.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34098.1 - 6.2e-07 29.4 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 PVD34099.1 - 5.7e-23 81.9 5.8 5.7e-23 81.9 5.8 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 PVD34099.1 - 5e-15 55.5 0.0 7.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Cation_ATPase_C PF00689.21 PVD34099.1 - 0.23 11.1 3.6 0.36 10.5 3.6 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus 7tm_3 PF00003.22 PVD34100.1 - 3.9e-28 98.8 6.3 4.8e-28 98.5 6.3 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Wzz PF02706.15 PVD34100.1 - 6.4 7.2 5.5 23 5.4 3.0 2.1 1 1 1 2 2 2 0 Chain length determinant protein DUF2722 PF10846.8 PVD34103.1 - 0.0016 17.5 9.0 0.0016 17.5 9.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RAB3GAP2_N PF14655.6 PVD34103.1 - 0.017 14.4 4.3 0.03 13.6 4.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Androgen_recep PF02166.16 PVD34103.1 - 0.93 8.3 16.7 1.6 7.5 16.7 1.3 1 0 0 1 1 1 0 Androgen receptor AAA_23 PF13476.6 PVD34103.1 - 1.3 9.5 12.9 1.9 9.0 12.9 1.2 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 PVD34103.1 - 3.2 8.0 9.4 5.5 7.2 9.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain eIF-3_zeta PF05091.12 PVD34103.1 - 3.7 6.4 14.7 5 6.0 14.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF775 PF05603.12 PVD34103.1 - 6.7 6.2 10.7 11 5.5 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4140 PF13600.6 PVD34104.1 - 5.4 7.5 7.4 1.7 9.2 1.0 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Abhydrolase_5 PF12695.7 PVD34105.1 - 0.0078 16.0 0.0 1.6 8.5 0.0 2.9 3 0 0 3 3 3 2 Alpha/beta hydrolase family Oxysterol_BP PF01237.18 PVD34107.1 - 1.1e-71 241.7 8.3 3.5e-71 240.0 0.4 3.1 2 1 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 PVD34107.1 - 1.2e-14 54.7 0.1 2.5e-13 50.4 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 PVD34107.1 - 2.4e-08 34.2 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 PVD34107.1 - 7e-06 26.3 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PVD34107.1 - 0.0017 18.8 0.9 0.021 15.2 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PVD34107.1 - 0.0031 17.9 3.3 0.0078 16.6 0.2 3.0 3 1 1 4 4 4 1 Pleckstrin homology domain PH_13 PF16652.5 PVD34107.1 - 0.0086 15.9 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Fuseless PF15993.5 PVD34108.1 - 0.01 15.1 0.9 0.017 14.3 0.9 1.3 1 0 0 1 1 1 0 Fuseless Ion_trans PF00520.31 PVD34108.1 - 0.023 14.0 0.5 0.038 13.2 0.5 1.2 1 0 0 1 1 1 0 Ion transport protein LIM PF00412.22 PVD34109.1 - 5e-25 87.5 22.7 5.5e-13 48.9 8.3 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 PVD34109.1 - 6.7e-05 22.4 14.8 0.6 9.7 0.1 4.6 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD34109.1 - 0.0012 18.9 26.4 0.94 9.6 0.3 4.2 4 0 0 4 4 4 4 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 PVD34109.1 - 0.012 15.6 2.3 1.7 8.8 0.4 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.6 PVD34109.1 - 0.023 14.4 30.0 0.49 10.2 0.2 6.2 6 0 0 6 6 6 0 zinc-ribbon domain zf-ACC PF17848.1 PVD34109.1 - 0.027 14.5 3.6 0.28 11.3 0.3 3.9 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 PVD34109.1 - 0.18 11.8 26.4 7.1 6.8 9.2 4.4 2 2 0 2 2 2 0 Double zinc ribbon SelR PF01641.18 PVD34109.1 - 0.24 11.5 8.5 1.5 8.9 0.7 2.2 2 0 0 2 2 2 0 SelR domain zf-ribbon_3 PF13248.6 PVD34109.1 - 0.47 9.9 0.1 0.47 9.9 0.1 5.1 6 0 0 6 6 6 0 zinc-ribbon domain MqsA_antitoxin PF15731.5 PVD34109.1 - 1 9.5 5.9 12 6.1 0.1 3.0 2 2 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-CCHC_5 PF14787.6 PVD34109.1 - 1.5 8.6 0.1 1.5 8.6 0.1 3.3 3 0 0 3 3 2 0 GAG-polyprotein viral zinc-finger TF_Zn_Ribbon PF08271.12 PVD34109.1 - 1.5 8.4 23.6 0.78 9.3 0.3 4.7 4 1 0 4 4 4 0 TFIIB zinc-binding Ribosomal_S27 PF01599.19 PVD34109.1 - 1.8 8.8 20.1 7.1 6.9 4.3 4.2 3 2 0 3 3 3 0 Ribosomal protein S27a Mu-like_Com PF10122.9 PVD34109.1 - 2.6 7.6 11.8 3 7.4 0.2 4.0 4 0 0 4 4 4 0 Mu-like prophage protein Com DUF2688 PF10892.8 PVD34109.1 - 6.1 6.4 10.6 11 5.5 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2688) NinD PF17466.2 PVD34109.1 - 6.8 6.9 10.6 14 5.9 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function LIM PF00412.22 PVD34111.1 - 4e-08 33.4 1.5 6.7e-08 32.6 1.5 1.4 1 0 0 1 1 1 1 LIM domain Zn_Tnp_IS1595 PF12760.7 PVD34111.1 - 0.082 12.9 3.4 0.27 11.2 3.4 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 PVD34111.1 - 0.85 9.3 0.1 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 PVD34111.1 - 2.9 7.9 6.2 1.5 8.8 2.8 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PMP22_Claudin PF00822.20 PVD34113.1 - 0.071 13.0 4.8 0.093 12.6 4.8 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family 7TM_GPCR_Srsx PF10320.9 PVD34114.1 - 2.4 7.4 4.5 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Kinesin PF00225.23 PVD34116.1 - 4.1e-113 377.7 1.3 5.8e-113 377.2 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD34116.1 - 3.1e-29 101.8 0.3 8.8e-29 100.4 0.3 1.8 1 0 0 1 1 1 1 Microtubule binding Spore_GerAC PF05504.11 PVD34116.1 - 0.018 15.3 0.8 0.059 13.6 0.3 2.1 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal SpecificRecomb PF10136.9 PVD34116.1 - 0.22 9.8 12.5 0.19 10.0 11.4 1.4 1 1 0 1 1 1 0 Site-specific recombinase DUF3037 PF11236.8 PVD34116.1 - 3.9 7.9 10.1 0.54 10.7 1.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3037) Cnn_1N PF07989.11 PVD34116.1 - 6.4 7.0 11.5 0.41 10.8 4.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 AATase PF07247.12 PVD34117.1 - 0.04 12.5 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase TK PF00265.18 PVD34117.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase Ldl_recept_b PF00058.17 PVD34118.1 - 7.9e-173 560.8 51.2 5.1e-12 46.1 0.0 20.6 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD34118.1 - 5.1e-47 157.8 108.2 2.3e-14 53.4 9.2 7.5 7 0 0 7 7 7 6 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 PVD34118.1 - 2.4e-42 142.8 97.7 2.8e-11 43.4 17.6 6.6 6 0 0 6 6 6 5 Low-density lipoprotein receptor domain class A SGL PF08450.12 PVD34118.1 - 5e-21 75.4 21.5 4.9e-06 26.3 0.4 10.3 3 2 3 8 8 8 5 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 PVD34118.1 - 2.6e-09 36.8 0.0 0.00088 18.6 0.0 5.8 5 2 2 7 7 7 2 Domain of unknown function (DUF5050) cEGF PF12662.7 PVD34118.1 - 7.7e-09 35.3 39.6 1.6e-05 24.7 0.9 6.9 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD34118.1 - 4e-06 26.9 8.0 4e-06 26.9 8.0 9.4 9 1 1 10 10 10 1 Calcium-binding EGF domain DUF4381 PF14316.6 PVD34118.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 2OG-FeII_Oxy_3 PF13640.6 PVD34119.1 - 1.8e-11 44.8 0.0 3.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 PVD34119.1 - 2e-05 23.9 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein PhyH PF05721.13 PVD34119.1 - 0.18 12.0 0.0 20 5.3 0.0 2.2 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Sod_Cu PF00080.20 PVD34122.1 - 0.007 16.5 0.1 0.009 16.2 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SH3_2 PF07653.17 PVD34123.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Peptidase_C1 PF00112.23 PVD34124.1 - 1.5e-14 54.6 0.2 2.5e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD34124.1 - 1.1e-10 41.7 2.2 1.9e-10 41.0 2.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 PVD34125.1 - 1.4e-29 103.8 0.2 1.4e-29 103.7 0.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PVD34125.1 - 0.0014 17.5 0.2 0.0018 17.1 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Ammonium_transp PF00909.21 PVD34126.1 - 5.3e-50 170.3 9.2 6.7e-50 169.9 9.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pox_A14 PF05767.12 PVD34126.1 - 0.065 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Ig_3 PF13927.6 PVD34127.1 - 1.2e-74 246.9 20.4 2.7e-13 50.3 0.0 10.8 11 0 0 11 11 10 6 Immunoglobulin domain I-set PF07679.16 PVD34127.1 - 3.8e-73 241.6 0.1 6.1e-15 55.1 0.0 7.7 8 0 0 8 8 8 5 Immunoglobulin I-set domain ig PF00047.25 PVD34127.1 - 1.4e-53 179.0 3.6 9.4e-09 35.3 0.0 9.2 9 0 0 9 9 9 6 Immunoglobulin domain Ig_2 PF13895.6 PVD34127.1 - 4.2e-43 145.6 7.9 2.4e-07 31.0 0.0 9.4 9 0 0 9 9 9 5 Immunoglobulin domain V-set PF07686.17 PVD34127.1 - 6.8e-27 93.8 15.6 1.2e-05 25.4 0.2 11.5 7 5 1 8 8 7 5 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD34127.1 - 7e-13 47.9 0.0 0.012 15.2 0.0 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Izumo-Ig PF16706.5 PVD34127.1 - 3.8e-10 39.7 0.1 5.3 7.2 0.0 6.3 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD34127.1 - 4.2e-10 39.5 4.7 0.6 10.2 0.0 8.1 9 0 0 9 9 8 2 C17orf99 Ig domain C2-set_2 PF08205.12 PVD34127.1 - 6e-09 35.9 13.7 0.048 13.7 0.0 7.9 9 0 0 9 9 9 3 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD34127.1 - 0.00021 21.0 0.0 7 6.5 0.0 5.3 5 0 0 5 5 5 2 Adenovirus E3 region protein CR1 RGM_N PF06535.12 PVD34127.1 - 0.00028 21.1 14.1 0.034 14.4 4.5 2.7 1 1 1 2 2 2 2 Repulsive guidance molecule (RGM) N-terminus Receptor_2B4 PF11465.8 PVD34127.1 - 0.00077 19.6 0.0 0.13 12.5 0.0 3.8 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 zf-RRN7 PF11781.8 PVD34127.1 - 0.0043 16.7 5.7 8.4 6.2 0.0 5.0 5 0 0 5 5 5 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PaaB PF06243.11 PVD34128.1 - 0.063 13.5 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Phenylacetic acid degradation B Lectin_C PF00059.21 PVD34129.1 - 4.4e-05 24.2 2.4 0.00011 22.9 2.4 1.7 1 0 0 1 1 1 1 Lectin C-type domain RVT_1 PF00078.27 PVD34130.1 - 5.5e-12 45.7 0.0 6.5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1155 PF06633.11 PVD34131.1 - 0.28 10.7 1.9 0.48 10.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) Med25_VWA PF11265.8 PVD34132.1 - 9.2e-79 264.2 0.0 1.4e-78 263.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.8 PVD34132.1 - 3.1e-51 173.3 0.1 6.6e-51 172.3 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 PDZ PF00595.24 PVD34133.1 - 1.9e-19 69.7 0.1 2.8e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 PVD34133.1 - 1.4e-15 56.8 0.0 3.4e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 PVD34133.1 - 1e-10 41.3 0.2 2.9e-10 39.8 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD34133.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 PDZ domain V-set PF07686.17 PVD34134.1 - 1.5e-06 28.3 0.2 2.1e-05 24.6 0.0 2.6 1 1 2 3 3 3 1 Immunoglobulin V-set domain Sec2p PF06428.11 PVD34134.1 - 0.0068 16.4 2.2 0.0068 16.4 2.2 1.6 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p SKA1 PF07160.12 PVD34134.1 - 0.034 14.0 0.4 0.048 13.5 0.4 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Atg14 PF10186.9 PVD34134.1 - 0.064 12.3 1.2 0.096 11.8 1.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lge1 PF11488.8 PVD34134.1 - 1.5 9.1 5.2 4 7.7 4.3 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Fibrinogen_C PF00147.18 PVD34135.1 - 6.2e-09 36.0 0.1 1e-08 35.3 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HMG_box_2 PF09011.10 PVD34135.1 - 0.0091 16.6 1.7 0.016 15.8 1.3 1.6 1 1 0 1 1 1 1 HMG-box domain TEX13 PF15186.6 PVD34136.1 - 5.1 6.8 6.8 1.1 9.0 1.2 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family ANAPC4_WD40 PF12894.7 PVD34137.1 - 2.2e-11 43.9 0.4 0.0046 17.2 0.1 3.8 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD34137.1 - 1e-06 29.3 3.7 5.2 8.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat IKI3 PF04762.12 PVD34137.1 - 0.00061 17.9 0.0 0.04 11.9 0.0 2.0 1 1 1 2 2 2 2 IKI3 family DUF5540 PF17694.1 PVD34138.1 - 2.1e-11 44.2 0.1 49 4.5 0.0 8.5 7 1 1 8 8 8 0 Family of unknown function (DUF5540) GH-E PF14410.6 PVD34138.1 - 2.5e-10 40.6 29.0 0.9 10.0 0.1 10.8 9 2 2 11 11 11 4 HNH/ENDO VII superfamily nuclease with conserved GHE residues ChaC PF04752.12 PVD34138.1 - 4.9e-10 39.7 22.1 3.6 7.6 0.1 7.9 4 2 4 8 8 8 7 ChaC-like protein DUF4464 PF14713.6 PVD34138.1 - 1.9e-09 37.4 32.7 0.00058 19.5 2.1 7.0 1 1 5 6 6 6 6 Domain of unknown function (DUF4464) RBR PF17208.3 PVD34138.1 - 0.00033 21.3 10.7 4.5e+02 1.7 0.0 9.8 9 2 1 11 11 11 0 RNA binding Region DUF1797 PF08796.10 PVD34138.1 - 0.0021 18.1 22.1 54 4.0 0.1 7.8 7 0 0 7 7 7 0 Protein of unknown function (DUF1797) Plasmid_stab_B PF10784.9 PVD34138.1 - 0.0054 16.5 0.2 7.2 6.5 0.0 3.5 1 1 1 2 2 2 2 Plasmid stability protein Inhibitor_I66 PF16850.5 PVD34138.1 - 0.26 11.2 5.8 3.7 7.4 0.5 4.0 2 1 1 3 3 3 0 Peptidase inhibitor I66 WD40_3 PF15911.5 PVD34139.1 - 2.3e-23 82.0 0.0 6.3e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.20 PVD34139.1 - 1.6e-10 41.0 5.3 0.0026 17.6 0.5 5.0 4 1 2 6 6 6 3 Region in Clathrin and VPS TPR_19 PF14559.6 PVD34139.1 - 0.00021 21.7 2.9 7 7.2 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD34139.1 - 0.0015 18.7 11.4 2.2 8.6 0.1 6.2 5 1 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PVD34139.1 - 0.0028 18.3 6.3 1.4 9.9 0.4 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat DZR PF12773.7 PVD34139.1 - 0.0073 16.3 5.3 0.072 13.1 5.3 2.3 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 PVD34139.1 - 0.039 13.4 9.4 0.1 12.0 1.9 3.4 3 0 0 3 3 3 0 zinc-ribbon domain TPR_7 PF13176.6 PVD34139.1 - 0.041 13.9 10.8 7.9 6.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 PVD34139.1 - 0.065 13.5 0.0 0.36 11.2 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD34139.1 - 0.15 13.0 0.1 2.5 9.1 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat TPR_2 PF07719.17 PVD34139.1 - 0.95 9.7 26.7 25 5.3 2.8 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 PVD34139.1 - 2.1 8.7 18.3 20 5.7 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PVD34139.1 - 4 7.4 8.7 45 4.0 0.7 4.0 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 ATG13 PF10033.9 PVD34140.1 - 5.6e-11 42.6 0.1 1.3e-06 28.3 0.1 3.1 1 1 1 2 2 2 2 Autophagy-related protein 13 Cadherin PF00028.17 PVD34141.1 - 1.5e-92 304.2 9.7 4.7e-21 75.0 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34141.1 - 6.4e-11 41.9 0.0 6.5e-07 29.1 0.0 4.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_pro PF08758.11 PVD34141.1 - 0.0095 16.1 0.0 0.4 10.9 0.0 3.2 3 0 0 3 3 3 1 Cadherin prodomain like Cadherin_3 PF16184.5 PVD34141.1 - 0.07 13.1 8.5 6.7 6.8 0.0 5.7 6 0 0 6 6 6 0 Cadherin-like PepSY PF03413.19 PVD34141.1 - 0.14 12.7 0.0 0.62 10.7 0.0 2.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Cadherin-like PF12733.7 PVD34141.1 - 0.4 11.2 8.5 0.13 12.8 0.3 3.9 4 0 0 4 4 4 0 Cadherin-like beta sandwich domain 7tm_1 PF00001.21 PVD34142.1 - 4.4e-37 127.8 24.1 3.9e-36 124.7 24.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD34142.1 - 0.00037 20.3 10.0 0.00037 20.3 10.0 2.3 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD34142.1 - 0.0019 17.6 14.8 0.0019 17.6 14.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tetraspanin PF00335.20 PVD34144.1 - 1.4e-22 80.5 13.2 1.7e-22 80.2 13.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4870 PF09685.10 PVD34144.1 - 0.05 13.7 6.4 0.067 13.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF2614 PF11023.8 PVD34144.1 - 0.098 12.8 3.2 0.2 11.7 3.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain SUR7 PF06687.12 PVD34144.1 - 0.13 11.9 4.6 0.15 11.7 4.6 1.2 1 0 0 1 1 1 0 SUR7/PalI family Herpes_LMP1 PF05297.11 PVD34144.1 - 0.22 10.7 4.2 0.26 10.4 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2207 PF09972.9 PVD34144.1 - 0.51 9.0 4.8 0.55 8.9 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VPDSG-CTERM PF18205.1 PVD34144.1 - 0.73 9.7 0.1 0.73 9.7 0.1 3.2 3 1 1 4 4 4 0 VPDSG-CTERM motif DUF4282 PF14110.6 PVD34144.1 - 1.3 9.8 10.4 2.7 8.8 10.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF202 PF02656.15 PVD34144.1 - 1.7 9.1 9.8 0.08 13.4 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) CrgA PF06781.12 PVD34144.1 - 2.4 8.3 5.8 0.24 11.5 0.9 1.8 2 0 0 2 2 2 0 Cell division protein CrgA ABC2_membrane_3 PF12698.7 PVD34144.1 - 3.2 6.8 10.3 3.9 6.5 10.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3040 PF11239.8 PVD34144.1 - 4.1 7.8 7.8 56 4.1 7.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF872 PF05915.12 PVD34144.1 - 4.7 7.4 10.5 0.9 9.7 3.0 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.6 PVD34144.1 - 5.3 6.7 10.6 0.88 9.3 2.4 2.4 1 1 1 2 2 2 0 Neurensin DUF2981 PF11200.8 PVD34144.1 - 8 6.1 7.4 11 5.6 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) DUF3043 PF11241.8 PVD34144.1 - 8.7 6.4 6.1 59 3.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) Gly_transf_sug PF04488.15 PVD34146.1 - 1.6e-08 35.1 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD34146.1 - 0.0053 16.2 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD34146.1 - 0.0083 15.5 0.1 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Tubulin_C PF03953.17 PVD34147.1 - 3.2e-43 146.9 0.1 4.5e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 PVD34147.1 - 3.7e-33 115.4 0.0 6.6e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 PVD34147.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.8 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Lig_chan-Glu_bd PF10613.9 PVD34148.1 - 2.4e-15 56.7 0.0 3.6e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD34148.1 - 8.9e-15 54.6 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 PVD34149.1 - 6e-42 143.0 2.0 6.6e-42 142.9 2.0 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan PF00060.26 PVD34150.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel DUF4064 PF13273.6 PVD34150.1 - 0.057 13.7 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ArsP_1 PF03773.13 PVD34150.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted permease SBP_bac_3 PF00497.20 PVD34150.1 - 0.14 11.5 0.3 0.24 10.8 0.3 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PVD34151.1 - 1.7e-49 167.5 0.5 2.5e-49 166.9 0.5 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD34151.1 - 1.5e-35 121.9 0.0 2.8e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD34151.1 - 1.3e-25 90.3 0.0 4.5e-24 85.2 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 PVD34151.1 - 1.3e-20 73.8 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 PVD34151.1 - 0.00044 20.0 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 2 Periplasmic binding protein RXT2_N PF08595.11 PVD34151.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CAP_N PF01213.19 PVD34151.1 - 0.81 9.1 2.1 1.4 8.3 2.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PVD34151.1 - 4.7 7.3 9.1 2.4 8.2 5.7 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Lig_chan PF00060.26 PVD34152.1 - 1.2e-47 161.5 2.8 1.9e-47 160.8 2.8 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 PVD34152.1 - 6.4e-11 42.0 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 PVD34152.1 - 4e-06 27.0 0.1 8.6e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Ion_trans_2 PF07885.16 PVD34152.1 - 2.9 7.9 9.1 3 7.9 1.7 2.5 1 1 1 2 2 2 0 Ion channel ANF_receptor PF01094.28 PVD34154.1 - 8.7e-42 143.5 2.1 1.1e-41 143.1 2.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 PVD34154.1 - 6.8e-18 64.9 0.5 3.7e-17 62.6 0.0 2.5 4 0 0 4 4 4 1 Ligated ion channel L-glutamate- and glycine-binding site Peripla_BP_6 PF13458.6 PVD34154.1 - 0.00041 20.1 0.5 0.035 13.8 0.1 2.1 2 0 0 2 2 2 2 Periplasmic binding protein SBP_bac_3 PF00497.20 PVD34154.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.7 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PVD34155.1 - 1.5e-59 200.1 1.2 2e-59 199.7 1.2 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD34155.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 PVD34155.1 - 4e-12 46.3 0.1 8.7e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD34157.1 - 3.5e-28 98.7 0.0 3.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 PVD34158.1 - 3.7e-10 39.4 0.0 4.4e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Exo_endo_phos_2 PF14529.6 PVD34160.1 - 2.3e-18 66.2 0.2 1.2e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD34160.1 - 1.2e-07 31.5 0.8 2.8e-07 30.3 0.3 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family MutS_IV PF05190.18 PVD34160.1 - 0.021 15.2 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 MutS family domain IV DUF1932 PF09130.11 PVD34160.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Streptin-Immun PF11083.8 PVD34160.1 - 0.057 13.8 0.3 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein RVT_1 PF00078.27 PVD34161.1 - 1.2e-12 47.9 0.3 1.9e-12 47.2 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PVD34162.1 - 1.8e-15 57.1 0.1 5.4e-13 49.0 0.1 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) P22_AR_N PF10547.9 PVD34162.1 - 0.021 15.1 0.6 4.3 7.7 0.0 2.7 2 1 0 2 2 2 0 P22_AR N-terminal domain Med7 PF05983.11 PVD34163.1 - 8.9e-46 156.4 4.8 3.5e-45 154.5 4.8 1.8 1 1 0 1 1 1 1 MED7 protein RNase_PH PF01138.21 PVD34164.1 - 1.1e-25 90.6 0.0 2.6e-25 89.4 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PVD34164.1 - 1.9e-08 34.2 0.0 3.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Zwilch PF09817.9 PVD34165.1 - 1.4e-46 159.2 0.0 2.5e-46 158.3 0.0 1.3 1 1 0 1 1 1 1 RZZ complex, subunit zwilch LIM PF00412.22 PVD34166.1 - 0.011 15.9 0.4 0.024 14.8 0.4 1.5 1 0 0 1 1 1 0 LIM domain DUF1924 PF09086.11 PVD34166.1 - 0.1 13.0 0.6 18 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Glutaredoxin PF00462.24 PVD34167.1 - 2.9e-08 33.8 0.0 7.5e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 PVD34167.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein ACPS PF01648.20 PVD34170.1 - 2.1e-15 56.9 0.0 1.1e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily HLH PF00010.26 PVD34171.1 - 1.4e-17 63.4 0.4 2.6e-17 62.5 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 PVD34171.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3474 PF11960.8 PVD34172.1 - 0.091 13.0 0.3 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) MRG PF05712.13 PVD34173.1 - 1.1e-44 152.1 0.4 2.1e-44 151.2 0.4 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 PVD34173.1 - 3.4e-05 23.6 0.0 7.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF229 PF02995.17 PVD34174.1 - 2.7e-34 118.6 2.1 4e-33 114.8 2.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD34174.1 - 0.00089 18.7 0.0 0.055 12.9 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 PVD34174.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily PH PF00169.29 PVD34175.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 PH domain FGGY_N PF00370.21 PVD34176.1 - 0.022 14.3 0.0 0.23 11.0 0.0 2.0 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain TMEM240 PF15207.6 PVD34176.1 - 0.026 14.2 0.0 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 TMEM240 family Astro_capsid_p PF12226.8 PVD34177.1 - 0.0099 15.1 2.1 0.0099 15.1 2.1 1.7 2 0 0 2 2 2 1 Turkey astrovirus capsid protein LIAS_N PF16881.5 PVD34179.1 - 1.6e-18 67.1 0.3 5.6e-18 65.3 0.3 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 PVD34179.1 - 4.4e-17 63.0 0.0 6.4e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Sugar-bind PF04198.13 PVD34179.1 - 0.0094 15.1 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 1 Putative sugar-binding domain Methyltransf_11 PF08241.12 PVD34180.1 - 4.1e-12 46.6 0.0 9.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD34180.1 - 4.6e-09 36.9 0.0 1.2e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD34180.1 - 4.6e-06 26.5 0.0 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD34180.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD34180.1 - 0.00013 22.6 1.1 0.00049 20.8 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD34180.1 - 0.0037 16.2 0.2 0.031 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 PVD34180.1 - 0.0037 16.6 0.0 0.0077 15.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 PVD34180.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FragX_IP PF05994.11 PVD34181.1 - 0 1329.2 1.9 0 1328.7 1.9 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 PVD34181.1 - 4.5e-08 32.7 7.5 4.1e-07 29.5 7.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) BP28CT PF08146.12 PVD34181.1 - 0.039 13.8 0.4 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 BP28CT (NUC211) domain ANAPC15 PF15243.6 PVD34182.1 - 2.5e-17 63.0 0.0 3.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 GDI PF00996.18 PVD34183.1 - 2.8e-58 197.5 0.0 2e-43 148.6 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 PVD34183.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fip1 PF05182.13 PVD34184.1 - 2.1e-23 81.6 1.6 4.7e-23 80.4 1.6 1.6 1 0 0 1 1 1 1 Fip1 motif DNMT1-RFD PF12047.8 PVD34184.1 - 0.9 9.6 3.5 0.28 11.2 0.3 1.7 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain RhoGAP PF00620.27 PVD34185.1 - 6e-41 139.8 0.0 1.6e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 PVD34185.1 - 4.7e-20 72.3 2.3 7.4e-20 71.7 2.3 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 PVD34185.1 - 5e-08 33.4 1.1 1.7e-07 31.7 0.1 2.2 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 PVD34186.1 - 9.6e-29 100.8 11.6 1.3e-28 100.4 11.6 1.1 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 PVD34186.1 - 0.00073 19.3 6.4 0.00081 19.1 6.4 1.1 1 0 0 1 1 1 1 BAR domain HEPN_Swt1 PF18731.1 PVD34186.1 - 0.0078 16.6 0.2 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Swt1-like HEPN BAR_2 PF10455.9 PVD34186.1 - 0.026 13.7 7.0 0.59 9.2 7.0 2.0 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 PVD34187.1 - 2e-52 178.3 16.9 4.1e-52 177.3 16.9 1.5 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 PVD34187.1 - 6.9e-14 51.9 0.0 1.9e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.6 PVD34187.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 PVD34187.1 - 9.7e-09 35.7 0.1 2.8e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 PVD34187.1 - 1.4e-07 31.0 0.0 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD34187.1 - 1.9e-06 27.5 0.0 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SusF_SusE PF16411.5 PVD34187.1 - 0.042 14.4 0.8 0.13 12.8 0.1 2.1 2 0 0 2 2 2 0 Outer membrane protein SusF_SusE Neur_chan_LBD PF02931.23 PVD34188.1 - 3.7e-14 52.7 0.3 1.2e-13 51.0 0.3 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD34189.1 - 8.2e-05 22.8 0.3 9.8e-05 22.5 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glycoprot_B_PH2 PF17417.2 PVD34191.1 - 0.05 13.9 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain LRR19-TM PF15176.6 PVD34192.1 - 0.21 11.6 0.0 0.49 10.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ANAPC4 PF12896.7 PVD34194.1 - 3.7e-58 196.4 7.1 7.1e-58 195.5 7.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 PVD34194.1 - 1e-29 102.6 0.3 2.7e-29 101.3 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5132 PF17195.4 PVD34194.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) GTP_EFTU PF00009.27 PVD34195.1 - 5.9e-33 114.0 0.0 5.9e-33 114.0 0.0 4.3 5 1 0 5 5 5 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PVD34195.1 - 5.2e-20 71.5 1.1 2e-19 69.7 0.1 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 PVD34195.1 - 7.5e-14 51.4 0.0 1.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 PVD34195.1 - 1.3e-06 28.7 16.9 4.4e-06 27.0 0.0 4.9 5 1 1 6 6 6 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PVD34195.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 4.1 6 0 0 6 6 6 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 PVD34195.1 - 0.009 15.8 0.0 0.009 15.8 0.0 2.8 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein MlaD PF02470.20 PVD34195.1 - 0.13 12.6 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 MlaD protein zf-NOSIP PF15906.5 PVD34197.1 - 4e-44 148.6 2.0 6.8e-44 147.9 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 PVD34197.1 - 1.6e-15 57.2 0.5 2e-15 56.9 0.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.15 PVD34197.1 - 2e-06 27.9 0.0 0.0063 16.7 0.0 2.3 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 PVD34197.1 - 0.00026 20.7 0.0 0.00089 19.0 0.0 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Forkhead PF00250.18 PVD34198.1 - 7.3e-33 112.7 0.1 1.3e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain SH3_9 PF14604.6 PVD34199.1 - 1.5e-08 34.4 0.0 4.9e-08 32.7 0.0 1.8 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 PVD34199.1 - 3.9e-08 32.8 0.0 3.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PVD34199.1 - 4.4e-07 29.4 0.0 8.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 PVD34202.1 - 0.054 13.8 0.1 0.23 11.8 0.0 2.1 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain CYTH PF01928.21 PVD34203.1 - 5.4e-13 49.3 0.1 1e-08 35.3 0.0 2.0 1 1 1 2 2 2 2 CYTH domain SET PF00856.28 PVD34204.1 - 0.0037 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 SET domain Ribosomal_L32e PF01655.18 PVD34205.1 - 2.1e-52 176.1 2.1 2.5e-52 175.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 LRR_8 PF13855.6 PVD34206.1 - 8.8e-54 179.1 55.6 6.3e-11 41.9 2.8 8.5 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 PVD34206.1 - 2.8e-37 126.1 65.8 6.5e-07 29.6 2.4 11.3 3 2 6 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD34206.1 - 1.7e-09 37.4 30.7 0.006 16.1 4.2 5.6 1 1 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 PVD34206.1 - 9.1e-09 34.7 45.7 7.5 7.5 0.0 15.8 16 2 0 16 16 16 3 Leucine Rich Repeat LRR_5 PF13306.6 PVD34206.1 - 8.5e-05 22.5 2.6 0.068 13.1 0.2 3.9 2 1 2 5 5 5 1 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 PVD34206.1 - 0.0018 18.3 1.1 51 4.0 0.0 6.0 4 2 3 7 7 7 0 RsmF rRNA methyltransferase first C-terminal domain IL11 PF07400.11 PVD34206.1 - 0.069 12.8 2.2 3.1 7.4 0.1 3.9 2 1 1 4 4 4 0 Interleukin 11 CSTF_C PF14304.6 PVD34206.1 - 0.19 11.3 7.4 4.3 7.0 0.1 4.9 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal LEDGF PF11467.8 PVD34206.1 - 0.64 9.6 4.4 15 5.2 0.2 3.8 3 1 1 4 4 4 0 Lens epithelium-derived growth factor (LEDGF) TANGO2 PF05742.12 PVD34207.1 - 1e-32 114.2 0.0 1.3e-32 113.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Thiolase_N PF00108.23 PVD34208.1 - 5.8e-89 297.9 0.0 8.6e-89 297.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD34208.1 - 2e-39 134.0 0.1 9.2e-39 131.9 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PVD34208.1 - 4.2e-05 23.2 0.6 0.00077 19.1 0.2 2.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 PVD34208.1 - 0.04 14.2 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Dodecin CBM_14 PF01607.24 PVD34209.1 - 1.3e-12 47.7 37.4 5.2e-08 32.9 4.6 3.9 4 1 0 4 4 4 3 Chitin binding Peritrophin-A domain CARDB PF07705.11 PVD34209.1 - 0.096 13.0 5.2 1.7 9.0 0.1 3.6 2 1 2 4 4 4 0 CARDB SSB PF00436.25 PVD34211.1 - 2.4e-22 79.0 0.3 3.4e-22 78.4 0.3 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 PVD34211.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IBN_N PF03810.19 PVD34212.1 - 1.2e-08 34.8 0.0 4e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Spore_YhaL PF14147.6 PVD34212.1 - 1.6 8.5 4.1 7.7 6.3 4.1 2.2 1 1 0 1 1 1 0 Sporulation protein YhaL BUD22 PF09073.10 PVD34212.1 - 2.3 7.5 11.1 3.5 6.9 11.1 1.2 1 0 0 1 1 1 0 BUD22 FSAP_sig_propep PF03032.15 PVD34212.1 - 6 7.0 6.6 0.73 9.9 1.2 2.3 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide Synaptobrevin PF00957.21 PVD34213.1 - 8.8e-29 99.1 0.9 1.4e-28 98.5 0.9 1.3 1 0 0 1 1 1 1 Synaptobrevin CD34_antigen PF06365.12 PVD34213.1 - 0.015 14.9 2.3 1 8.9 1.0 2.1 1 1 1 2 2 2 0 CD34/Podocalyxin family MCU PF04678.13 PVD34213.1 - 0.036 14.2 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EOS1 PF12326.8 PVD34213.1 - 0.051 13.5 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein TMEM154 PF15102.6 PVD34213.1 - 0.075 12.9 0.8 0.093 12.6 0.4 1.5 1 1 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD34213.1 - 0.079 13.7 1.4 12 6.7 0.1 2.3 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Ferlin_C PF16165.5 PVD34213.1 - 0.08 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus EphA2_TM PF14575.6 PVD34213.1 - 0.13 13.2 0.6 1.3 10.0 0.2 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 PVD34213.1 - 0.29 11.8 1.9 4.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2937 PF11157.8 PVD34213.1 - 0.38 10.4 2.4 0.96 9.1 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) OppC_N PF12911.7 PVD34213.1 - 7.6 6.6 5.8 5.8 7.0 0.5 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Lig_chan PF00060.26 PVD34216.1 - 1.5e-46 158.0 0.0 2.2e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD34216.1 - 1.5e-38 131.6 0.1 6.1e-38 129.6 0.0 2.0 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 PVD34216.1 - 4.2e-24 85.3 0.0 5.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 PVD34216.1 - 1.2e-22 80.4 0.0 2.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phage_holin_2_2 PF10746.9 PVD34216.1 - 0.12 12.1 0.1 0.33 10.7 0.1 1.8 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II ScsC_N PF18312.1 PVD34216.1 - 0.13 12.1 0.3 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain UxuA PF03786.13 PVD34216.1 - 0.15 10.8 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 D-mannonate dehydratase (UxuA) Arm PF00514.23 PVD34217.1 - 5.8e-37 124.6 18.6 7.7e-07 28.9 0.0 10.2 11 0 0 11 11 10 6 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 PVD34217.1 - 3.9e-35 121.4 0.0 3.2e-34 118.4 0.0 2.3 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 PVD34217.1 - 3.6e-19 68.9 8.8 0.00053 20.3 0.3 5.5 4 2 1 5 5 5 5 HEAT repeats HEAT PF02985.22 PVD34217.1 - 7.2e-12 44.5 13.0 0.38 11.2 0.0 8.2 8 0 0 8 8 8 5 HEAT repeat V-ATPase_H_C PF11698.8 PVD34217.1 - 6.7e-09 35.9 3.0 0.0028 17.8 0.1 5.2 4 1 1 5 5 5 2 V-ATPase subunit H HEAT_EZ PF13513.6 PVD34217.1 - 8.5e-07 29.4 11.1 0.13 12.8 0.0 7.2 7 1 0 7 7 7 1 HEAT-like repeat Cnd1 PF12717.7 PVD34217.1 - 9.5e-07 29.0 10.8 0.19 11.7 1.9 4.8 2 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 PVD34217.1 - 3.8e-05 23.1 1.8 0.17 11.2 0.2 3.3 2 1 1 3 3 3 2 V-ATPase subunit H UNC45-central PF11701.8 PVD34217.1 - 0.0062 16.5 0.8 6.3 6.7 0.1 3.3 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central NopRA1 PF16201.5 PVD34217.1 - 0.02 14.5 0.9 9.8 5.7 0.0 3.7 2 2 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 CCDC53 PF10152.9 PVD34217.1 - 1.3 9.4 6.3 2.3 8.6 3.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 PVD34217.1 - 3.9 7.6 9.2 15 5.8 3.8 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RasGEF_N_2 PF14663.6 PVD34217.1 - 7 7.1 11.5 41 4.6 0.2 4.9 3 3 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MIEAP PF16026.5 PVD34218.1 - 1.1e-36 126.9 0.7 6.5e-36 124.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondria-eating protein UPF0242 PF06785.11 PVD34218.1 - 0.0031 17.6 3.2 0.0031 17.6 3.2 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 PVD34218.1 - 0.013 14.9 5.7 0.024 14.1 5.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Mitofilin PF09731.9 PVD34218.1 - 0.018 13.9 6.4 0.028 13.3 6.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CALCOCO1 PF07888.11 PVD34218.1 - 0.02 13.8 11.1 0.028 13.3 11.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PV-1 PF06637.11 PVD34218.1 - 0.057 12.2 4.2 0.095 11.5 4.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Snapin_Pallidin PF14712.6 PVD34218.1 - 0.086 13.3 5.8 0.4 11.1 4.0 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Filament PF00038.21 PVD34218.1 - 0.11 12.1 12.0 0.42 10.2 12.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein SPATA1_C PF15743.5 PVD34218.1 - 0.27 11.3 12.2 0.22 11.6 6.1 2.8 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus Fez1 PF06818.15 PVD34218.1 - 0.45 10.9 10.6 1.2 9.6 10.6 1.7 1 0 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 PVD34218.1 - 0.49 10.6 5.9 1.2 9.3 5.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 PVD34218.1 - 0.49 10.7 11.8 0.19 12.1 3.8 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 PVD34218.1 - 0.55 10.7 3.7 1.7 9.1 1.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 PVD34218.1 - 0.59 10.1 10.8 0.58 10.1 5.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 PVD34218.1 - 0.76 9.8 16.1 0.43 10.7 12.3 2.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 PVD34218.1 - 0.81 10.6 11.1 2.8 8.9 10.6 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Fzo_mitofusin PF04799.13 PVD34218.1 - 1.5 8.4 5.7 2.6 7.6 5.7 1.4 1 0 0 1 1 1 0 fzo-like conserved region Spc7 PF08317.11 PVD34218.1 - 2 7.2 14.1 12 4.7 13.6 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 PVD34218.1 - 2.7 8.3 10.5 84 3.5 10.5 2.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 PVD34218.1 - 3.2 7.6 9.4 0.72 9.7 0.7 3.1 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.18 PVD34218.1 - 4.2 7.8 10.1 12 6.3 0.5 4.1 3 1 1 4 4 4 0 TSC-22/dip/bun family OmpH PF03938.14 PVD34218.1 - 4.8 7.5 13.4 0.42 10.9 7.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HDV_ag PF01517.18 PVD34218.1 - 7.4 6.3 5.6 14 5.4 2.7 2.2 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen MFS_1 PF07690.16 PVD34220.1 - 9.5e-19 67.5 33.1 3e-08 33.0 13.1 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 PVD34221.1 - 2e-06 27.0 34.3 0.00084 18.4 13.8 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF3591 PF12157.8 PVD34222.1 - 4.8e-155 516.5 0.9 4.8e-155 516.5 0.9 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 PVD34222.1 - 7.6e-39 131.7 4.3 9.7e-19 67.2 0.3 2.8 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 PVD34222.1 - 2.8e-20 72.3 4.4 2.8e-20 72.3 4.4 2.2 2 0 0 2 2 2 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 PVD34222.1 - 5.3e-14 51.8 2.3 2.2e-13 49.8 2.3 2.1 1 0 0 1 1 1 1 Zinc knuckle DUF334 PF03904.13 PVD34222.1 - 8.7 5.8 8.0 27 4.2 8.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF3591 PF12157.8 PVD34224.1 - 1.4e-152 508.5 0.3 2.7e-152 507.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 PVD34224.1 - 7.2e-39 131.7 5.5 1.5e-19 69.8 0.4 2.8 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 PVD34224.1 - 9.9e-15 54.5 0.8 3.1e-14 53.0 0.8 1.9 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 PVD34224.1 - 8.1e-11 41.6 0.3 2.8e-10 39.8 0.3 2.0 1 0 0 1 1 1 1 Zinc knuckle PI_PP_I PF18363.1 PVD34224.1 - 0.77 10.0 3.2 1.4 9.2 0.2 2.9 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain FNIP_N PF14636.6 PVD34224.1 - 0.99 10.4 4.2 20 6.2 0.1 3.4 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus zf-RING_11 PF17123.5 PVD34225.1 - 9.6e-05 22.0 2.1 0.00011 21.8 0.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger CrgA PF06781.12 PVD34225.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein CrgA zf-RING_2 PF13639.6 PVD34225.1 - 0.0031 17.8 0.7 0.0063 16.8 0.7 1.5 1 0 0 1 1 1 1 Ring finger domain PspB PF06667.12 PVD34225.1 - 0.017 15.2 0.2 0.041 13.9 0.2 1.6 1 0 0 1 1 1 0 Phage shock protein B Asp5 PF17000.5 PVD34225.1 - 0.056 13.6 1.8 0.11 12.6 1.8 1.5 1 1 0 1 1 1 0 Accessory secretory protein Sec, Asp5 PEN-2 PF10251.9 PVD34225.1 - 0.081 13.4 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase DUF4577 PF15145.6 PVD34225.1 - 0.099 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) zf-C3HC4_2 PF13923.6 PVD34225.1 - 0.1 12.5 0.9 0.22 11.4 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4448 PF14610.6 PVD34225.1 - 0.12 12.1 0.2 3.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) zf-C3HC4 PF00097.25 PVD34225.1 - 0.14 12.1 1.2 0.29 11.0 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cadherin PF00028.17 PVD34226.1 - 2.9e-23 82.1 0.2 5e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 PVD34227.1 - 2.8e-21 75.8 0.1 5.7e-14 52.3 0.1 2.4 2 0 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 PVD34228.1 - 1.9e-93 307.1 17.0 3.6e-20 72.2 0.1 7.1 7 0 0 7 7 7 6 Cadherin domain Y_Y_Y PF07495.13 PVD34228.1 - 0.00055 19.8 0.5 3 7.9 0.1 4.3 3 0 0 3 3 3 1 Y_Y_Y domain Cadherin_2 PF08266.12 PVD34228.1 - 0.012 15.4 0.0 23 4.9 0.0 4.4 4 1 1 5 5 5 0 Cadherin-like He_PIG PF05345.12 PVD34228.1 - 0.15 12.3 5.0 2.9 8.2 0.0 4.9 6 0 0 6 6 6 0 Putative Ig domain Cadherin PF00028.17 PVD34229.1 - 1.5e-30 105.5 0.0 7e-12 45.6 0.0 4.0 4 0 0 4 4 4 3 Cadherin domain Cadherin_3 PF16184.5 PVD34229.1 - 0.01 15.8 1.3 0.42 10.6 0.1 3.3 4 0 0 4 4 4 0 Cadherin-like AMIN PF11741.8 PVD34229.1 - 0.059 13.5 0.2 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AMIN domain DDE_Tnp_1_7 PF13843.6 PVD34230.1 - 5.5e-07 29.2 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Alpha-amylase PF00128.24 PVD34230.1 - 6.7e-06 25.9 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PVD34230.1 - 6.4e-05 23.4 0.0 0.0002 21.8 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain UCH PF00443.29 PVD34232.1 - 8.6e-42 143.4 0.0 1.4e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD34232.1 - 3e-23 82.9 0.0 5.7e-21 75.4 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase AAA_2 PF07724.14 PVD34233.1 - 4e-23 82.4 0.0 2.8e-11 43.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 PVD34233.1 - 2.2e-17 63.4 0.7 6.8e-09 36.2 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD34233.1 - 1.3e-16 60.2 1.4 5e-08 33.0 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PVD34233.1 - 1.2e-15 57.7 0.2 3.4e-09 37.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34233.1 - 4e-15 55.7 0.2 8.4e-07 29.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34233.1 - 2.4e-14 52.0 1.7 8.1e-06 25.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat ClpB_D2-small PF10431.9 PVD34233.1 - 5.6e-08 32.7 1.2 2.7e-07 30.5 0.1 2.7 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein YchF-GTPase_C PF06071.13 PVD34233.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Glucosamine_iso PF01182.20 PVD34234.1 - 2.9e-17 63.3 0.0 4.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GP17 PF17420.2 PVD34234.1 - 0.018 15.2 0.0 0.67 10.1 0.0 2.3 2 1 0 2 2 2 0 Superinfection exclusion gene product 17 MFS_1 PF07690.16 PVD34235.1 - 3.1e-09 36.2 7.8 4.2e-09 35.8 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 PVD34236.1 - 6.9e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nup54 PF13874.6 PVD34236.1 - 0.05 13.7 5.5 0.21 11.7 5.5 2.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YabA PF06156.13 PVD34236.1 - 1.2 9.8 8.6 0.6 10.8 0.6 3.4 3 1 1 4 4 4 0 Initiation control protein YabA KLRAQ PF10205.9 PVD34236.1 - 1.5 9.1 6.0 8.6 6.7 0.4 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein EBP PF05241.12 PVD34237.1 - 1.6e-07 30.9 6.3 2e-07 30.6 6.3 1.1 1 0 0 1 1 1 1 Emopamil binding protein Cadherin PF00028.17 PVD34238.1 - 3.7e-80 264.5 2.5 1.3e-14 54.4 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34238.1 - 2.3e-09 37.0 0.1 9.5e-07 28.6 0.0 4.3 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 PVD34238.1 - 0.00012 22.0 0.4 2 8.4 0.0 4.5 4 0 0 4 4 4 1 Cadherin-like EphA2_TM PF14575.6 PVD34238.1 - 0.017 16.0 0.0 0.039 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_4 PF17803.1 PVD34238.1 - 0.1 13.2 33.8 0.029 15.0 1.9 5.5 6 0 0 6 6 6 0 Bacterial cadherin-like domain ETF_QO PF05187.13 PVD34239.1 - 4.8e-48 161.6 0.1 8e-48 160.9 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 PVD34239.1 - 7.5e-09 35.2 0.7 8.3e-06 25.1 0.6 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 PVD34239.1 - 1.1e-08 35.1 0.1 6.9e-05 22.6 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PVD34239.1 - 1.7e-06 27.5 0.3 2.4e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PVD34239.1 - 2.8e-06 26.7 0.1 0.00013 21.3 0.1 2.2 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 PVD34239.1 - 6.3e-06 26.3 0.2 2.4e-05 24.5 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PVD34239.1 - 4.4e-05 22.3 0.5 6.8e-05 21.7 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PVD34239.1 - 6.1e-05 23.5 0.4 0.00027 21.5 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PVD34239.1 - 6.3e-05 23.0 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 PVD34239.1 - 0.00041 19.7 0.3 0.0017 17.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 PVD34239.1 - 0.0012 18.2 0.2 0.0021 17.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PVD34239.1 - 0.0014 17.5 0.6 0.012 14.5 0.3 2.0 1 1 1 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 PVD34239.1 - 0.0023 17.3 0.6 0.0036 16.7 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PVD34239.1 - 0.0035 16.5 0.1 0.0048 16.0 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 PVD34239.1 - 0.016 14.3 0.2 0.02 14.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.7 PVD34239.1 - 0.017 15.7 1.0 0.017 15.7 1.0 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 PVD34239.1 - 0.06 12.6 0.2 0.099 11.9 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_9 PF13187.6 PVD34239.1 - 0.1 12.8 2.0 0.51 10.6 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain MCRA PF06100.11 PVD34239.1 - 0.31 9.8 0.1 0.43 9.3 0.1 1.1 1 0 0 1 1 1 0 MCRA family Fer4_2 PF12797.7 PVD34239.1 - 5 7.4 5.7 0.48 10.6 0.7 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Cyt-b5 PF00173.28 PVD34240.1 - 9.2e-15 54.6 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Drf_GBD PF06371.13 PVD34245.1 - 0.21 11.1 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain BBS2_Mid PF14783.6 PVD34246.1 - 0.00011 22.2 0.0 0.00069 19.6 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 PVD34246.1 - 0.0019 17.0 0.8 0.024 13.4 0.1 2.5 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal ANAPC4_WD40 PF12894.7 PVD34246.1 - 0.14 12.5 0.0 13 6.1 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MAPEG PF01124.18 PVD34247.1 - 5.9e-14 52.1 4.6 7.2e-13 48.6 1.0 2.5 2 1 0 2 2 2 2 MAPEG family DUF116 PF01976.17 PVD34247.1 - 0.091 12.3 0.0 1.5 8.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF116 Alpha-amylase PF00128.24 PVD34248.1 - 0.016 14.7 0.2 0.12 11.9 0.2 2.0 1 1 0 1 1 1 0 Alpha amylase, catalytic domain Herpes_U30 PF04523.13 PVD34248.1 - 0.076 10.9 0.1 0.12 10.2 0.1 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 RMI1_N PF08585.12 PVD34249.1 - 3.3e-22 79.3 0.5 1.5e-17 64.1 0.0 3.1 2 1 1 3 3 3 2 RecQ mediated genome instability protein UBA PF00627.31 PVD34249.1 - 2.6e-09 36.8 0.0 5.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain SMN PF06003.12 PVD34249.1 - 5.5e-09 35.7 0.0 5.5e-09 35.7 0.0 3.0 2 2 2 4 4 4 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 PVD34249.1 - 0.0002 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 PVD34249.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Raftlin PF15250.6 PVD34249.1 - 1.6 7.4 6.1 3.1 6.4 6.1 1.4 1 0 0 1 1 1 0 Raftlin FH2 PF02181.23 PVD34250.1 - 1.2e-90 304.3 23.2 1.2e-90 304.3 23.2 3.2 3 1 1 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD34250.1 - 1.6e-45 155.1 2.4 2.6e-45 154.5 0.0 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PVD34250.1 - 2.4e-38 131.6 0.0 2.4e-38 131.6 0.0 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.11 PVD34250.1 - 0.00049 19.9 0.4 0.0013 18.6 0.4 1.8 1 0 0 1 1 1 1 DRF Autoregulatory Domain Mito_fiss_reg PF05308.11 PVD34250.1 - 0.00056 20.1 2.6 0.00056 20.1 2.6 3.0 3 0 0 3 3 3 1 Mitochondrial fission regulator Cnn_1N PF07989.11 PVD34250.1 - 0.042 14.0 0.6 0.042 14.0 0.6 4.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 MetOD2 PF18548.1 PVD34250.1 - 0.12 12.5 6.2 5 7.3 0.7 3.6 3 0 0 3 3 3 0 Metanogen output domain 2 FlaC_arch PF05377.11 PVD34250.1 - 0.19 12.1 5.5 14 6.2 0.1 3.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1493 PF07377.12 PVD34250.1 - 1.3 9.6 5.8 5.3 7.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Drf_GBD PF06371.13 PVD34251.1 - 2.6e-16 59.7 0.1 2.6e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PVD34251.1 - 7.2e-13 48.6 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain FH2 PF02181.23 PVD34252.1 - 3.2e-90 303.0 12.3 3.2e-90 303.0 12.3 2.7 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD34252.1 - 0.00027 20.6 3.4 0.00031 20.4 0.0 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_DAD PF06345.11 PVD34252.1 - 0.0025 17.7 0.7 0.006 16.5 0.7 1.7 1 0 0 1 1 1 1 DRF Autoregulatory Domain FlxA PF14282.6 PVD34252.1 - 0.28 11.2 16.7 0.23 11.5 0.5 4.1 3 0 0 3 3 3 0 FlxA-like protein DNA_pol3_gamma3 PF12169.8 PVD34252.1 - 0.39 10.6 4.3 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III T3SSipB PF16535.5 PVD34252.1 - 1.7 9.1 17.2 0.63 10.5 0.4 3.8 4 0 0 4 4 4 0 Type III cell invasion protein SipB Histone_HNS PF00816.21 PVD34252.1 - 1.8 9.4 14.1 22 6.0 2.8 3.8 3 0 0 3 3 3 0 H-NS histone family Laminin_II PF06009.12 PVD34252.1 - 1.9 8.5 12.0 0.79 9.7 0.5 3.7 4 0 0 4 4 4 0 Laminin Domain II DNA_pack_N PF02500.15 PVD34252.1 - 6.3 6.5 9.4 0.6 9.9 0.7 2.8 2 1 1 3 3 3 0 Probable DNA packing protein, N-terminus SNF PF00209.18 PVD34253.1 - 5.3e-164 546.8 27.0 2.3e-147 491.9 18.2 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family SNF PF00209.18 PVD34254.1 - 4.8e-208 692.1 32.9 5.5e-208 691.9 32.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family WW PF00397.26 PVD34255.1 - 1.5e-14 53.7 0.6 1.2e-07 31.7 0.0 2.7 3 0 0 3 3 3 2 WW domain HrpB7 PF09486.10 PVD34255.1 - 0.015 15.7 1.4 0.08 13.3 0.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CtIP_N PF10482.9 PVD34255.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain HMMR_N PF15905.5 PVD34255.1 - 0.077 12.5 8.5 0.11 12.0 8.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spectrin PF00435.21 PVD34255.1 - 0.13 12.8 9.3 0.13 12.8 0.5 2.4 2 0 0 2 2 2 0 Spectrin repeat Spc7 PF08317.11 PVD34255.1 - 3.1 6.6 12.4 5.3 5.8 2.5 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 PVD34255.1 - 5.4 6.7 7.5 3.1 7.5 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LPD34 PF18852.1 PVD34256.1 - 0.09 12.4 1.2 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 FTA4 PF13093.6 PVD34256.1 - 0.74 9.7 9.9 1.1 9.1 1.8 2.8 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 LURAP PF14854.6 PVD34256.1 - 4.5 7.3 12.8 0.078 12.9 3.5 2.9 3 0 0 3 3 3 0 Leucine rich adaptor protein MeaB PF03308.16 PVD34257.1 - 4.2e-79 265.3 1.3 2e-78 263.1 1.3 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 PVD34257.1 - 6.3e-07 29.1 0.1 7.9e-06 25.6 0.1 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 PVD34257.1 - 7.6e-05 22.5 0.1 0.0002 21.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 PVD34257.1 - 0.00018 21.4 0.5 0.00039 20.3 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PVD34257.1 - 0.001 19.3 1.1 0.0033 17.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PVD34257.1 - 0.0025 17.6 0.2 0.0059 16.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 PVD34257.1 - 0.0046 17.0 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 PVD34257.1 - 0.0068 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.17 PVD34257.1 - 0.0072 16.0 0.2 0.091 12.4 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 PVD34257.1 - 0.032 14.8 0.2 0.16 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PVD34257.1 - 0.062 13.8 0.8 0.16 12.4 0.1 2.0 2 1 0 2 2 2 0 ABC transporter PRK PF00485.18 PVD34257.1 - 0.08 12.7 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 PVD34257.1 - 0.093 12.8 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD34257.1 - 0.1 12.9 0.2 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain GvpG PF05120.12 PVD34257.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G AAA_29 PF13555.6 PVD34257.1 - 0.14 11.9 1.5 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 PVD34257.1 - 0.14 12.3 0.2 0.4 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Ubiq_cyt_C_chap PF03981.12 PVD34257.1 - 1.9 8.5 4.5 1.9 8.5 1.9 2.2 2 1 1 3 3 3 0 Ubiquinol-cytochrome C chaperone Glyco_hydro_15 PF00723.21 PVD34258.1 - 1.5e-151 505.2 0.0 1.8e-151 504.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ank_2 PF12796.7 PVD34259.1 - 8e-37 125.7 0.0 2.7e-16 59.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD34259.1 - 6.2e-28 93.8 0.8 6e-05 23.1 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 PVD34259.1 - 1.3e-27 95.8 0.6 5.4e-07 30.1 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34259.1 - 1.1e-25 89.4 1.2 4.7e-09 36.3 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD34259.1 - 1.2e-23 82.5 3.1 0.019 15.4 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat DHHC PF01529.20 PVD34259.1 - 2.5e-17 63.2 12.6 2.5e-17 63.2 12.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase SDA1 PF05285.12 PVD34260.1 - 3e-65 220.9 31.7 3.8e-37 128.5 5.9 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 PVD34260.1 - 1e-20 73.8 1.9 1.5e-20 73.2 0.1 2.3 2 0 0 2 2 2 1 NUC130/3NT domain zf-rbx1 PF12678.7 PVD34260.1 - 1.2e-08 35.1 5.5 3.8e-08 33.5 5.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PVD34260.1 - 5.6e-06 26.3 4.1 1.2e-05 25.3 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tli4_C PF18426.1 PVD34260.1 - 0.04 14.2 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Fucokinase PF07959.12 PVD34261.1 - 6.6e-106 354.6 0.1 7.7e-106 354.4 0.1 1.0 1 0 0 1 1 1 1 L-fucokinase Aminotran_1_2 PF00155.21 PVD34261.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II P_gingi_FimA PF06321.11 PVD34261.1 - 0.16 12.1 0.0 2.4 8.2 0.0 2.3 1 1 0 2 2 2 0 Major fimbrial subunit protein (FimA) zf-C2H2 PF00096.26 PVD34262.1 - 1.9e-13 50.0 25.7 2.5e-05 24.5 2.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD34262.1 - 3.6e-10 39.8 11.1 9.5e-08 32.1 1.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD34262.1 - 7.8e-05 23.2 26.1 0.0032 18.2 1.9 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD34262.1 - 0.0088 16.0 1.0 0.0088 16.0 1.0 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 PVD34262.1 - 0.24 11.5 6.7 3.3 7.8 1.7 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 PVD34262.1 - 7.8 7.0 12.2 0.46 11.0 0.2 3.9 4 1 1 5 5 5 0 Zinc-finger of C2H2 type KDZ PF18758.1 PVD34264.1 - 2.7e-42 144.9 0.0 6.2e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 PVD34264.1 - 1.4e-10 41.2 0.0 4.9e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 PVD34264.1 - 1.2e-08 35.0 0.0 3.4e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases GTF2I PF02946.14 PVD34265.1 - 2.4e-19 69.2 0.0 5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 GTF2I-like repeat YchF-GTPase_C PF06071.13 PVD34265.1 - 0.0028 17.8 0.3 14 6.0 0.0 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF933) Sgf11_N PF18519.1 PVD34265.1 - 0.012 15.1 0.1 7.9 6.1 0.0 2.6 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain Calpain_III PF01067.22 PVD34265.1 - 0.1 12.8 0.8 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Calpain large subunit, domain III Peptidase_C12 PF01088.21 PVD34266.1 - 2.6e-55 187.4 0.4 1.9e-54 184.6 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 7TM_GPCR_Srw PF10324.9 PVD34267.1 - 4.4e-13 49.2 24.3 2.3e-06 27.2 9.5 3.3 3 0 0 3 3 3 3 Serpentine type 7TM GPCR chemoreceptor Srw Arch_flagellin PF01917.16 PVD34267.1 - 1.3e-05 25.5 0.4 0.51 10.5 0.1 3.3 3 0 0 3 3 3 3 Archaebacterial flagellin DUF5426 PF17473.2 PVD34267.1 - 0.086 13.1 1.0 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5426) 7tm_1 PF00001.21 PVD34268.1 - 7.2e-05 22.2 0.1 7.9e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD34268.1 - 9.5e-05 21.8 3.2 0.00024 20.5 3.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1600 PF07667.11 PVD34268.1 - 0.1 12.8 3.9 0.15 12.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) ASC PF00858.24 PVD34269.1 - 1e-26 93.9 3.3 4e-16 59.0 0.0 3.1 2 1 1 3 3 3 3 Amiloride-sensitive sodium channel 7TM_GPCR_Srw PF10324.9 PVD34270.1 - 5.9e-12 45.5 0.9 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD34270.1 - 3.9e-06 26.4 0.6 0.00085 18.7 0.5 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD34270.1 - 0.028 14.1 0.2 0.052 13.2 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.6 PVD34271.1 - 8.8e-21 73.4 28.9 3.2e-07 30.0 0.4 7.3 5 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 PVD34271.1 - 2.1e-13 50.2 23.8 0.0058 17.0 0.3 8.0 6 1 2 8 8 8 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD34271.1 - 7.1e-06 26.6 0.0 1.7e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD34271.1 - 1.3e-05 25.1 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRRCT PF01463.24 PVD34271.1 - 0.082 13.5 3.6 0.71 10.6 0.1 3.2 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 PVD34271.1 - 0.13 12.3 13.7 1.5 9.1 0.0 7.0 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 PVD34271.1 - 0.29 11.8 21.4 31 5.6 0.1 9.4 7 2 1 8 8 8 0 Leucine Rich Repeat DUF3948 PF13134.6 PVD34271.1 - 0.42 10.3 4.0 1.4 8.7 4.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) LRR_9 PF14580.6 PVD34271.1 - 2.7 7.5 8.1 19 4.7 0.0 3.9 4 1 1 6 6 6 0 Leucine-rich repeat Glyco_hydro_18 PF00704.28 PVD34272.1 - 4.5e-84 282.8 0.2 5.4e-84 282.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nup160 PF11715.8 PVD34272.1 - 0.0088 14.7 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Methyltransf_FA PF12248.8 PVD34273.1 - 2.5e-18 66.3 0.0 1.5e-16 60.6 0.0 2.7 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase Gal-3-0_sulfotr PF06990.11 PVD34274.1 - 9.7e-50 169.6 6.3 1.5e-25 90.0 0.9 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PVD34274.1 - 0.2 11.5 0.9 0.66 9.8 0.0 2.2 3 1 0 3 3 3 0 Sulfotransferase family zf-C3HC4_3 PF13920.6 PVD34275.1 - 9.7e-06 25.4 7.9 1.8e-05 24.5 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD34275.1 - 9.1e-05 22.7 8.1 0.00024 21.4 8.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD34275.1 - 0.00015 21.6 9.1 0.00037 20.3 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD34275.1 - 0.0016 18.7 7.9 0.0048 17.2 7.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 PVD34275.1 - 0.002 17.7 6.1 0.0054 16.4 6.1 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4 PF00097.25 PVD34275.1 - 0.0038 17.1 8.9 0.0098 15.7 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Wtap PF17098.5 PVD34275.1 - 0.0057 16.6 0.2 0.0057 16.6 0.2 3.1 3 1 0 3 3 3 1 WTAP/Mum2p family Prok-RING_4 PF14447.6 PVD34275.1 - 0.018 14.9 8.3 0.039 13.8 8.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD34275.1 - 0.029 14.3 7.5 0.062 13.3 7.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain XhlA PF10779.9 PVD34275.1 - 0.05 13.8 0.2 0.05 13.8 0.2 3.0 3 0 0 3 3 2 0 Haemolysin XhlA zf-RING_UBOX PF13445.6 PVD34275.1 - 0.069 13.2 5.6 0.2 11.7 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PVD34275.1 - 0.16 11.8 4.1 0.35 10.7 4.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SlyX PF04102.12 PVD34275.1 - 0.19 12.4 0.2 0.19 12.4 0.2 3.4 3 0 0 3 3 3 0 SlyX PEP-utilisers_N PF05524.13 PVD34275.1 - 0.73 10.0 2.4 2 8.6 0.0 2.6 3 0 0 3 3 2 0 PEP-utilising enzyme, N-terminal Zn_ribbon_17 PF17120.5 PVD34275.1 - 1.2 8.8 4.7 2.9 7.6 4.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 PVD34275.1 - 1.4 9.1 4.7 3.5 7.8 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Shugoshin_N PF07558.11 PVD34275.1 - 1.4 8.8 6.2 13 5.8 1.0 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Sulfotransfer_3 PF13469.6 PVD34276.1 - 9.2e-07 29.5 0.1 2.1e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD34276.1 - 6.4e-05 22.6 0.2 0.00011 21.8 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 PVD34276.1 - 0.051 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Cadherin PF00028.17 PVD34278.1 - 1.2e-83 275.7 0.0 2.2e-15 56.8 0.0 7.4 6 1 1 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34278.1 - 1.3e-10 40.9 0.8 2.7e-07 30.3 0.0 3.7 4 0 0 4 4 4 2 Cadherin-like Adeno_E3_CR2 PF02439.15 PVD34278.1 - 0.025 14.3 1.0 0.065 13.0 1.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 PVD34282.1 - 6e-96 315.1 6.6 4.1e-19 68.8 0.1 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34282.1 - 1.1e-11 44.4 0.0 3.3e-06 26.9 0.0 5.4 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 PVD34282.1 - 4.6e-08 33.0 10.9 0.16 12.0 0.1 5.6 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 PVD34282.1 - 0.0016 19.1 32.3 1.6 9.4 0.1 6.7 5 1 0 5 5 5 2 Bacterial cadherin-like domain Big_9 PF17963.1 PVD34282.1 - 0.022 15.5 36.0 0.65 10.8 2.2 6.8 5 1 1 6 6 6 0 Bacterial Ig domain Cadherin_pro PF08758.11 PVD34282.1 - 0.043 14.0 0.0 13 6.0 0.0 3.1 3 0 0 3 3 3 0 Cadherin prodomain like Como_LCP PF02247.16 PVD34282.1 - 0.057 12.0 0.0 0.12 11.0 0.0 1.5 1 0 0 1 1 1 0 Large coat protein Glyco_hydro2_C5 PF18565.1 PVD34282.1 - 0.058 13.2 0.5 17 5.3 0.1 3.3 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 MCM PF00493.23 PVD34285.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SOR_SNZ PF01680.17 PVD34285.1 - 0.13 12.0 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 SOR/SNZ family C1_1 PF00130.22 PVD34286.1 - 3.1e-07 30.2 13.0 3.1e-07 30.2 13.0 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ_6 PF17820.1 PVD34286.1 - 1.8e-06 27.7 0.2 4.1e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 PDZ domain MMM1 PF10296.9 PVD34286.1 - 4e-06 26.1 2.3 1.1e-05 24.6 0.0 2.7 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PDZ_2 PF13180.6 PVD34286.1 - 2.4e-05 24.6 0.4 6.7e-05 23.1 0.4 1.8 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 PVD34286.1 - 9.9e-05 22.6 0.0 0.00082 19.6 0.0 2.6 3 0 0 3 3 3 1 C2 domain PDZ PF00595.24 PVD34286.1 - 0.019 15.3 0.4 0.049 14.0 0.4 1.7 1 0 0 1 1 1 0 PDZ domain PHY PF00360.20 PVD34286.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Phytochrome region C1_2 PF03107.16 PVD34286.1 - 1.2 9.6 12.1 0.38 11.1 6.4 2.6 2 0 0 2 2 2 0 C1 domain PHD_4 PF16866.5 PVD34286.1 - 4 7.6 14.4 0.28 11.3 4.5 3.3 4 0 0 4 4 4 0 PHD-finger RabGAP-TBC PF00566.18 PVD34287.1 - 1.8e-40 138.9 0.0 4.7e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 PVD34287.1 - 6.4e-13 48.8 2.2 1.5e-12 47.6 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) PID PF00640.23 PVD34287.1 - 7.3e-08 32.6 9.3 0.0015 18.6 0.2 4.5 4 0 0 4 4 4 2 Phosphotyrosine interaction domain (PTB/PID) Syntaxin PF00804.25 PVD34287.1 - 1 9.0 10.6 1.1 8.9 0.0 3.4 3 0 0 3 3 3 0 Syntaxin TSC22 PF01166.18 PVD34287.1 - 1.5 9.2 8.4 5.2 7.5 0.8 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family KfrA_N PF11740.8 PVD34287.1 - 6.3 7.5 9.9 62 4.3 5.4 3.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Somatomedin_B PF01033.17 PVD34288.1 - 0.031 14.7 11.3 0.11 13.0 11.3 1.9 1 0 0 1 1 1 0 Somatomedin B domain HobA PF12163.8 PVD34288.1 - 0.048 13.2 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA replication regulator TMEM232 PF15877.5 PVD34290.1 - 1.3e-73 248.6 0.6 8.6e-62 209.6 0.5 2.2 2 0 0 2 2 2 2 Transmembrane protein family 232 bZIP_1 PF00170.21 PVD34292.1 - 0.021 14.9 4.1 0.021 14.9 4.1 9.6 7 2 4 11 11 11 0 bZIP transcription factor Tox-REase-5 PF15648.6 PVD34292.1 - 1.8 9.1 7.5 1.9 9.1 1.4 3.3 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF1848 PF08902.11 PVD34292.1 - 3.3 7.3 13.8 0.076 12.7 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) F-box-like PF12937.7 PVD34293.1 - 3e-09 36.6 0.3 7.3e-09 35.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD34293.1 - 2.4e-08 33.6 0.2 5e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD34293.1 - 0.023 14.6 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 F-box WD40 PF00400.32 PVD34293.1 - 0.11 13.4 0.8 13 6.8 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat RabGAP-TBC PF00566.18 PVD34294.1 - 6.1e-36 124.1 0.1 1.2e-35 123.2 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PVD34294.1 - 6.1e-32 111.0 0.0 9.5e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34294.1 - 2e-16 60.0 0.0 4.5e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 PVD34294.1 - 1.4e-09 38.4 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 PVD34294.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PIH1_CS PF18201.1 PVD34295.1 - 0.02 15.3 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 PIH1 CS-like domain zf-RING_2 PF13639.6 PVD34296.1 - 2e-07 31.2 6.4 3.6e-07 30.4 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD34296.1 - 5.1e-05 23.5 7.6 0.00011 22.4 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PVD34296.1 - 6.3e-05 22.8 6.7 0.00013 21.8 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD34296.1 - 0.00069 19.5 6.2 0.0013 18.7 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD34296.1 - 0.0011 19.0 1.2 0.0019 18.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PVD34296.1 - 0.0021 17.9 4.4 0.0071 16.2 4.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD34296.1 - 0.0035 17.1 3.9 0.01 15.6 3.9 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PVD34296.1 - 0.0054 16.7 3.2 0.024 14.7 3.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger DZR PF12773.7 PVD34296.1 - 0.0067 16.4 0.1 0.014 15.4 0.1 1.5 1 1 0 1 1 1 1 Double zinc ribbon YhfH PF14149.6 PVD34296.1 - 0.026 14.5 0.1 0.026 14.5 0.1 2.1 3 0 0 3 3 2 0 YhfH-like protein zf-C3HC4_4 PF15227.6 PVD34296.1 - 0.033 14.3 2.5 0.033 14.3 2.5 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD34296.1 - 0.035 14.0 8.0 0.15 11.9 8.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PVD34296.1 - 0.079 13.2 7.7 1.7 8.9 7.7 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 PVD34296.1 - 0.083 12.8 7.2 0.4 10.6 7.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PVD34296.1 - 0.11 12.2 8.0 0.45 10.2 8.0 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 PVD34296.1 - 0.2 12.0 1.4 0.56 10.5 0.3 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.21 PVD34296.1 - 0.23 12.1 2.0 3.2 8.5 0.0 2.3 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain A2L_zn_ribbon PF08792.10 PVD34296.1 - 0.58 9.9 0.1 0.58 9.9 0.1 2.6 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-UDP PF14569.6 PVD34296.1 - 0.75 10.0 7.0 0.42 10.8 4.4 1.9 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-ribbon_3 PF13248.6 PVD34296.1 - 2.7 7.5 5.2 2.5 7.6 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF92 PF01940.16 PVD34296.1 - 3.1 7.1 9.0 15 4.9 9.0 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF92 Ion_trans PF00520.31 PVD34297.1 - 7.8e-29 100.6 15.6 1.2e-28 100.0 15.6 1.3 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 PVD34297.1 - 4.9e-21 74.9 9.4 1.2e-20 73.6 9.4 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 PVD34297.1 - 1.2e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF948 PF06103.11 PVD34297.1 - 0.072 13.4 1.5 2.9 8.2 0.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5446 PF17522.2 PVD34297.1 - 0.075 13.2 4.2 0.097 12.8 2.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Nup54 PF13874.6 PVD34297.1 - 0.27 11.3 4.4 3.3 7.8 1.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ion_trans_2 PF07885.16 PVD34297.1 - 0.42 10.6 13.8 0.049 13.6 7.8 2.6 3 1 0 3 3 3 0 Ion channel Halogen_Hydrol PF10112.9 PVD34297.1 - 0.48 10.4 3.9 0.42 10.6 1.1 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Cadherin PF00028.17 PVD34299.1 - 2.2e-75 249.2 5.3 8e-13 48.6 0.0 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34299.1 - 1e-13 50.9 1.3 2.6e-11 43.2 0.0 4.6 6 0 0 6 6 6 1 Cadherin-like Cadherin_3 PF16184.5 PVD34299.1 - 3.2e-05 23.9 7.2 1.9 8.5 0.1 5.3 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 PVD34299.1 - 0.029 15.0 0.6 0.029 15.0 0.6 5.2 6 0 0 6 6 6 0 Bacterial cadherin-like domain MIB_HERC2 PF06701.13 PVD34301.1 - 1.4e-15 57.3 11.0 6e-11 42.4 3.1 2.7 2 0 0 2 2 2 2 Mib_herc2 VWA_2 PF13519.6 PVD34301.1 - 1.7e-10 41.5 0.1 5e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PVD34301.1 - 0.00017 21.9 0.0 0.00051 20.3 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1216 PF06746.11 PVD34301.1 - 0.042 13.8 0.9 0.18 11.8 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) PCB_OB PF17092.5 PVD34301.1 - 0.051 14.3 0.0 5.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain V_ATPase_I PF01496.19 PVD34301.1 - 1.5 6.6 8.2 3 5.7 8.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MIB_HERC2 PF06701.13 PVD34302.1 - 1.3e-09 38.1 2.1 1.3e-09 38.1 2.1 3.2 4 0 0 4 4 4 2 Mib_herc2 WWE PF02825.20 PVD34302.1 - 4.3e-07 30.4 0.5 1.5e-06 28.7 0.5 2.0 1 0 0 1 1 1 1 WWE domain Cep57_CLD PF14073.6 PVD34302.1 - 0.097 12.7 3.1 1.7 8.6 5.5 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 MIB_HERC2 PF06701.13 PVD34303.1 - 1.1e-07 32.0 5.6 1.1e-07 32.0 5.6 2.1 2 0 0 2 2 2 1 Mib_herc2 VWA_2 PF13519.6 PVD34303.1 - 2.4e-06 28.1 0.0 1e-05 26.1 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain WWE PF02825.20 PVD34303.1 - 3.5e-06 27.5 0.1 3.5e-06 27.5 0.1 2.6 2 0 0 2 2 2 1 WWE domain VWA PF00092.28 PVD34303.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain IgGFc_binding PF17517.2 PVD34304.1 - 2.3e-22 79.7 16.9 5.6e-13 48.8 0.1 4.1 2 1 2 4 4 4 3 IgGFc binding protein EGF PF00008.27 PVD34304.1 - 3.1e-07 30.5 13.7 0.0038 17.5 4.9 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 PVD34304.1 - 0.0014 19.2 0.7 0.0014 19.2 0.7 3.2 3 0 0 3 3 3 2 Human growth factor-like EGF HemY_N PF07219.13 PVD34304.1 - 0.085 13.1 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 HemY protein N-terminus MGC-24 PF05283.11 PVD34304.1 - 3.9 7.9 15.2 1.3 9.5 11.8 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EGF_CA PF07645.15 PVD34304.1 - 9.1 6.6 27.5 0.59 10.4 7.7 2.9 2 1 1 3 3 3 0 Calcium-binding EGF domain DUF4537 PF15057.6 PVD34305.1 - 3.8e-53 178.6 1.6 5.1e-24 84.6 0.0 4.6 3 1 1 4 4 4 4 Domain of unknown function (DUF4537) VWA_3 PF13768.6 PVD34305.1 - 1.3e-21 77.2 5.0 1.7e-17 63.8 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA PF00092.28 PVD34305.1 - 2.5e-12 47.4 0.1 1.6e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD34305.1 - 1.6e-06 28.7 0.1 2.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Tudor_2 PF18104.1 PVD34305.1 - 1.7e-05 24.4 2.4 0.55 10.0 0.1 5.0 5 0 0 5 5 5 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 PVD34305.1 - 1.7e-05 24.5 1.6 0.7 9.8 0.0 5.6 5 1 1 6 6 6 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 PVD34305.1 - 0.0063 16.9 0.0 11 6.6 0.0 3.6 3 0 0 3 3 3 1 Agenet domain TUDOR_5 PF18359.1 PVD34305.1 - 0.0096 15.6 0.1 0.35 10.6 0.0 3.3 4 0 0 4 4 4 1 Histone methyltransferase Tudor domain 1 CAF1 PF04857.20 PVD34306.1 - 2.3e-10 40.2 0.4 8.8e-08 31.7 0.1 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease Mod_r PF07200.13 PVD34307.1 - 6.7e-26 91.1 13.6 6.7e-26 91.1 13.6 1.5 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Cluap1 PF10234.9 PVD34307.1 - 2.2 7.6 9.8 0.57 9.5 5.6 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 WD40 PF00400.32 PVD34308.1 - 1.8e-25 88.7 27.6 7.8e-05 23.4 0.0 10.1 10 0 0 10 10 10 6 WD domain, G-beta repeat EF-hand_7 PF13499.6 PVD34308.1 - 8e-11 42.2 0.0 2.3e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD34308.1 - 3.9e-09 35.4 0.1 6.4e-05 22.2 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD34308.1 - 8.1e-08 32.0 0.0 2.9e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD34308.1 - 3.9e-07 29.5 0.1 0.0018 18.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain ANAPC4_WD40 PF12894.7 PVD34308.1 - 1.5e-06 28.4 0.1 0.0078 16.5 0.0 5.2 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD34308.1 - 0.00011 21.0 7.2 0.076 11.7 0.2 3.9 2 1 1 4 4 4 2 Nucleoporin Nup120/160 EF-hand_5 PF13202.6 PVD34308.1 - 0.00023 20.5 0.1 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 PVD34308.1 - 0.08 13.3 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain RanGAP1_C PF07834.11 PVD34310.1 - 8.2e-48 162.4 0.3 1.3e-47 161.8 0.3 1.3 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.6 PVD34310.1 - 6.5e-26 88.1 17.4 6.7e-05 22.6 0.0 9.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 PVD34310.1 - 1e-08 35.3 6.3 0.09 13.2 0.1 4.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD34310.1 - 0.0059 17.0 8.1 47 5.1 0.0 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD34310.1 - 0.47 10.2 14.6 2.5 7.9 0.1 5.0 3 2 0 3 3 3 0 Leucine rich repeat tRNA_bind PF01588.20 PVD34311.1 - 3.6e-30 103.9 0.1 7.5e-30 102.9 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain HALZ PF02183.18 PVD34311.1 - 0.11 12.7 1.3 0.23 11.7 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Arrestin_C PF02752.22 PVD34311.1 - 0.38 11.2 4.9 8 6.9 0.3 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Myc-LZ PF02344.15 PVD34311.1 - 0.55 10.4 2.0 1.1 9.5 2.0 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain tRNA-synt_2 PF00152.20 PVD34313.1 - 4.5e-38 131.1 0.0 4.5e-38 131.1 0.0 3.0 3 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) CCCAP PF15964.5 PVD34313.1 - 6.9e-08 31.3 97.4 9.5e-07 27.5 97.4 2.4 1 1 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Tropomyosin_1 PF12718.7 PVD34313.1 - 0.0027 17.9 7.1 0.0027 17.9 7.1 7.1 2 1 4 7 7 7 3 Tropomyosin like APG6_N PF17675.1 PVD34313.1 - 3.9 8.0 114.7 0.3 11.6 15.6 6.9 1 1 6 7 7 7 0 Apg6 coiled-coil region Ank_2 PF12796.7 PVD34314.1 - 5.9e-27 94.1 0.4 5.2e-09 36.6 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34314.1 - 4.3e-26 90.9 1.0 5.4e-06 26.9 0.0 6.9 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34314.1 - 4e-25 85.1 1.4 3.4e-06 27.0 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 PVD34314.1 - 1.1e-18 66.8 4.7 0.0001 22.5 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 PVD34314.1 - 2.7e-17 62.6 0.5 5.1e-07 29.8 0.0 5.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD34314.1 - 2.8e-11 43.6 1.0 7.2e-11 42.3 1.0 1.7 1 0 0 1 1 1 1 SOCS box AHH PF14412.6 PVD34314.1 - 0.023 14.7 0.0 0.082 13.0 0.0 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF2370 PF10176.9 PVD34315.1 - 4.3e-06 26.5 4.0 1.1e-05 25.3 4.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) S-antigen PF05756.11 PVD34316.1 - 0.17 12.2 0.1 0.54 10.6 0.1 2.0 2 0 0 2 2 2 0 S-antigen protein SelP_N PF04592.14 PVD34317.1 - 0.18 11.2 7.4 0.23 10.8 7.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TIR PF01582.20 PVD34325.1 - 3.8e-13 49.6 0.0 3.8e-13 49.6 0.0 1.9 2 0 0 2 2 1 1 TIR domain TIR_2 PF13676.6 PVD34325.1 - 7.2e-11 42.7 0.0 5.3e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 TIR domain DUF2722 PF10846.8 PVD34325.1 - 0.00043 19.3 4.1 0.00056 19.0 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 PVD34325.1 - 0.00096 20.1 0.5 0.002 19.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4175 PF13779.6 PVD34325.1 - 0.027 12.4 4.9 0.037 12.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LRRCT PF01463.24 PVD34325.1 - 0.029 14.9 0.0 0.092 13.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Neur_chan_memb PF02932.16 PVD34325.1 - 0.03 14.4 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 PVD34325.1 - 0.033 14.5 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Cadherin_C_2 PF16492.5 PVD34325.1 - 0.048 14.4 0.1 0.092 13.5 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TFIIA PF03153.13 PVD34325.1 - 0.056 13.4 8.8 0.076 13.0 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UxuA PF03786.13 PVD34325.1 - 0.096 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) LRR_4 PF12799.7 PVD34325.1 - 0.12 12.9 0.2 3.7 8.1 0.2 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) FixS PF03597.15 PVD34325.1 - 0.26 11.0 1.9 0.47 10.2 1.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Spt20 PF12090.8 PVD34325.1 - 0.27 10.8 18.4 0.41 10.2 18.4 1.2 1 0 0 1 1 1 0 Spt20 family LRRNT PF01462.18 PVD34325.1 - 0.63 9.7 7.0 0.12 12.1 2.6 2.2 2 0 0 2 2 1 0 Leucine rich repeat N-terminal domain Med15 PF09606.10 PVD34325.1 - 1.1 7.9 15.6 1.5 7.5 15.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Roughex PF06020.11 PVD34325.1 - 2.2 7.3 4.8 3.2 6.8 4.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 PVD34325.1 - 3.1 6.2 7.6 4.2 5.7 7.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LRR_8 PF13855.6 PVD34326.1 - 2e-20 72.3 5.8 2.5e-06 27.2 0.2 4.5 2 2 2 4 4 4 4 Leucine rich repeat TIR PF01582.20 PVD34326.1 - 1.1e-12 48.1 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD34326.1 - 4.7e-09 36.9 0.0 1.1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD34326.1 - 2.2e-07 31.0 12.7 0.045 14.2 0.5 6.0 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD34326.1 - 1.8e-06 27.6 2.8 0.0017 17.9 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PVD34326.1 - 0.0008 19.3 0.7 15 6.0 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 PVD34326.1 - 0.0062 16.9 4.1 23 6.0 0.0 6.1 7 0 0 7 7 6 0 Leucine Rich Repeat LRRCT PF01463.24 PVD34326.1 - 0.035 14.6 0.0 0.12 12.9 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRRNT PF01462.18 PVD34326.1 - 0.066 12.9 3.1 0.55 9.9 2.4 3.1 2 1 0 2 2 2 0 Leucine rich repeat N-terminal domain Dfp1_Him1_M PF08630.10 PVD34326.1 - 0.079 13.2 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Dfp1/Him1, central region MHYT PF03707.16 PVD34326.1 - 0.29 11.3 1.9 0.68 10.1 1.9 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Lig_chan-Glu_bd PF10613.9 PVD34327.1 - 9.2e-31 106.4 0.0 1.6e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD34327.1 - 1.1e-26 93.4 0.2 1.8e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD34327.1 - 2.3e-10 40.3 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD34327.1 - 2.4e-10 40.1 0.1 4e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region DUF5083 PF16890.5 PVD34327.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Lig_chan PF00060.26 PVD34329.1 - 1.2e-43 148.5 0.1 2e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD34329.1 - 1.7e-39 134.6 0.0 3.4e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD34329.1 - 1.7e-16 60.4 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD34329.1 - 3.4e-11 42.9 0.1 2.7e-06 26.7 0.0 2.5 2 1 1 3 3 3 2 Receptor family ligand binding region U6-snRNA_bdg PF10596.9 PVD34329.1 - 0.1 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 Ion_trans_2 PF07885.16 PVD34329.1 - 4.4 7.3 9.0 0.25 11.4 1.9 2.4 2 0 0 2 2 2 0 Ion channel FXa_inhibition PF14670.6 PVD34330.1 - 6.8e-16 58.3 33.8 8e-12 45.2 10.5 3.8 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site Sushi PF00084.20 PVD34330.1 - 2.3e-15 56.9 16.5 3e-06 27.7 0.1 5.3 4 2 1 5 5 5 3 Sushi repeat (SCR repeat) cEGF PF12662.7 PVD34330.1 - 9.3e-08 31.9 2.7 9.3e-08 31.9 2.7 4.9 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD34330.1 - 3e-07 30.5 31.7 4.5e-05 23.6 9.6 3.7 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF PF00008.27 PVD34330.1 - 3e-05 24.2 24.1 0.00051 20.3 8.0 4.0 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 PVD34330.1 - 0.0031 17.7 26.7 0.012 15.8 9.7 3.2 2 0 0 2 2 2 2 EGF domain PMR5N PF14416.6 PVD34330.1 - 0.01 16.2 0.2 0.44 10.9 0.0 2.7 2 0 0 2 2 2 1 PMR5 N terminal Domain zf-C2H2 PF00096.26 PVD34332.1 - 2.9e-07 30.6 16.3 0.00068 19.9 4.2 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD34332.1 - 5.6e-07 29.9 11.5 0.053 14.4 0.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD34332.1 - 4.2e-06 26.9 4.8 4.1e-05 23.8 0.2 3.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-SNAP50_C PF12251.8 PVD34332.1 - 0.0038 16.9 0.3 0.012 15.3 0.2 1.9 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal C1_4 PF07975.12 PVD34332.1 - 0.075 13.3 3.8 4 7.8 1.3 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain zf-met PF12874.7 PVD34332.1 - 0.25 11.8 6.7 9.9 6.7 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PVD34332.1 - 4.7 7.1 7.4 11 5.8 1.9 3.2 2 1 1 3 3 3 0 zinc-finger C2H2-type EGF_CA PF07645.15 PVD34333.1 - 1.2e-07 31.8 6.9 1.2e-07 31.8 6.9 1.8 2 0 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD34333.1 - 1e-05 25.7 5.3 1e-05 25.7 5.3 2.2 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PVD34333.1 - 0.033 14.4 3.2 0.033 14.4 3.2 2.0 2 0 0 2 2 2 0 EGF domain hEGF PF12661.7 PVD34333.1 - 0.14 12.8 1.6 0.14 12.8 1.6 2.3 3 0 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.6 PVD34334.1 - 1e-31 108.9 70.5 1.3e-08 35.0 11.2 6.5 5 2 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 PVD34334.1 - 1.1e-30 105.5 65.0 1.9e-08 34.4 3.0 6.3 5 1 1 6 6 6 5 Calcium-binding EGF domain cEGF PF12662.7 PVD34334.1 - 6.9e-24 83.4 46.3 7.2e-08 32.2 1.6 7.3 6 1 0 6 6 6 6 Complement Clr-like EGF-like EGF PF00008.27 PVD34334.1 - 3.2e-11 43.3 63.9 0.00055 20.2 0.6 7.5 5 4 2 7 7 7 6 EGF-like domain EGF_3 PF12947.7 PVD34334.1 - 2.7e-07 30.6 63.5 0.041 14.1 2.8 7.7 4 2 2 6 6 6 5 EGF domain hEGF PF12661.7 PVD34334.1 - 0.00017 22.0 59.2 0.063 13.9 5.3 8.5 8 2 1 9 9 9 5 Human growth factor-like EGF Sushi PF00084.20 PVD34335.1 - 8.8e-13 48.6 25.1 1.8e-07 31.7 4.4 4.1 2 1 1 4 4 4 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 PVD34335.1 - 1.1e-10 41.6 11.3 1.1e-10 41.6 11.3 4.6 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD34335.1 - 4.2e-09 36.2 22.6 4.3e-05 23.3 2.0 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD34335.1 - 2.6e-07 30.7 11.1 2.6e-07 30.7 11.1 4.6 4 1 0 4 4 4 1 Calcium-binding EGF domain EGF_3 PF12947.7 PVD34335.1 - 0.0012 18.9 6.3 0.0012 18.9 6.3 4.7 4 0 0 4 4 4 1 EGF domain EGF PF00008.27 PVD34335.1 - 0.005 17.1 7.0 0.005 17.1 7.0 4.2 4 0 0 4 4 4 1 EGF-like domain TIL PF01826.17 PVD34335.1 - 0.43 10.9 28.5 0.43 10.9 2.0 4.7 2 2 2 4 4 4 0 Trypsin Inhibitor like cysteine rich domain Actin PF00022.19 PVD34336.1 - 1.3e-77 261.1 0.0 1.3e-75 254.5 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PVD34336.1 - 0.00011 21.1 0.0 0.00039 19.4 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 PVD34336.1 - 0.018 15.4 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA COMM_domain PF07258.14 PVD34337.1 - 3e-17 62.5 1.4 7.6e-17 61.2 0.4 2.0 2 0 0 2 2 2 1 COMM domain PCM1_C PF15717.5 PVD34338.1 - 1.6e-112 377.3 17.0 1.6e-112 377.3 17.0 5.9 4 3 1 5 5 5 1 Pericentriolar material 1 C terminus C1q PF00386.21 PVD34339.1 - 1.1e-25 90.3 0.5 1.9e-13 50.8 0.0 3.0 3 0 0 3 3 2 2 C1q domain ERM PF00769.19 PVD34339.1 - 0.00066 19.6 6.2 0.00066 19.6 6.2 3.6 3 1 0 3 3 3 2 Ezrin/radixin/moesin family Lebercilin PF15619.6 PVD34339.1 - 0.0013 18.5 23.1 0.0013 18.5 23.1 4.1 3 1 0 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease CcmH PF03918.14 PVD34339.1 - 0.0051 16.1 0.8 0.73 9.1 0.0 2.7 2 0 0 2 2 2 1 Cytochrome C biogenesis protein GAS PF13851.6 PVD34339.1 - 0.0065 15.8 4.3 0.0065 15.8 4.3 5.5 3 2 3 6 6 6 4 Growth-arrest specific micro-tubule binding HALZ PF02183.18 PVD34339.1 - 0.052 13.8 0.6 0.052 13.8 0.6 6.6 7 0 0 7 7 6 0 Homeobox associated leucine zipper PA14 PF07691.12 PVD34339.1 - 0.1 12.4 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 PA14 domain Spc7 PF08317.11 PVD34339.1 - 0.23 10.3 59.6 0.017 14.0 7.6 5.0 3 2 2 5 5 5 0 Spc7 kinetochore protein EzrA PF06160.12 PVD34339.1 - 0.68 8.0 42.5 0.59 8.2 3.6 4.7 2 2 2 4 4 4 0 Septation ring formation regulator, EzrA ZapB PF06005.12 PVD34339.1 - 1.6 9.2 52.5 0.15 12.5 2.3 7.1 5 2 1 6 6 6 0 Cell division protein ZapB She9_MDM33 PF05546.11 PVD34339.1 - 1.9 8.2 21.0 7.2 6.4 0.8 4.0 2 1 1 3 3 3 0 She9 / Mdm33 family APG6_N PF17675.1 PVD34339.1 - 2 9.0 58.1 0.2 12.2 12.5 6.7 3 2 2 5 5 4 0 Apg6 coiled-coil region Rootletin PF15035.6 PVD34339.1 - 2.4 8.1 50.7 0.059 13.4 8.7 5.2 3 2 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 PVD34339.1 - 4.1 7.9 28.2 2.2 8.7 0.8 7.3 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) C1q PF00386.21 PVD34340.1 - 1.1e-13 51.5 0.0 3.6e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 C1q domain zf-NPL4 PF05020.15 PVD34340.1 - 0.0019 18.3 0.2 0.0019 18.3 0.2 2.9 3 0 0 3 3 3 1 NPL4 family, putative zinc binding region HALZ PF02183.18 PVD34340.1 - 0.006 16.8 2.5 0.006 16.8 2.5 3.4 4 0 0 4 4 4 1 Homeobox associated leucine zipper zf-B_box PF00643.24 PVD34340.1 - 0.0082 16.3 7.6 0.0082 16.3 7.6 2.4 2 0 0 2 2 2 1 B-box zinc finger BLOC1_2 PF10046.9 PVD34340.1 - 0.096 13.0 13.3 1.4 9.3 1.3 3.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zinc_ribbon_4 PF13717.6 PVD34340.1 - 0.22 11.5 0.2 0.22 11.5 0.2 3.3 2 1 1 3 3 3 0 zinc-ribbon domain Prefoldin_2 PF01920.20 PVD34340.1 - 1.3 9.0 21.5 2.1 8.4 0.3 4.4 3 1 1 4 4 4 0 Prefoldin subunit XhlA PF10779.9 PVD34340.1 - 2.7 8.3 11.9 5.6 7.3 0.2 3.9 4 1 0 4 4 4 0 Haemolysin XhlA Spc7 PF08317.11 PVD34340.1 - 4 6.2 27.5 3.4 6.5 15.8 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 PVD34340.1 - 4.2 7.9 14.8 1.6 9.3 2.2 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein MRPL52 PF18699.1 PVD34340.1 - 5.8 7.2 6.8 21 5.4 0.2 3.2 2 1 0 2 2 2 0 Mitoribosomal protein mL52 C1q PF00386.21 PVD34341.1 - 2.3e-13 50.4 0.9 4.8e-13 49.4 0.0 2.1 3 0 0 3 3 1 1 C1q domain zf-RING_UBOX PF13445.6 PVD34341.1 - 4.8e-08 32.9 6.5 4.8e-08 32.9 6.5 2.9 2 0 0 2 2 1 1 RING-type zinc-finger APG6_N PF17675.1 PVD34341.1 - 0.00022 21.8 52.8 0.014 15.9 7.0 5.4 2 2 3 5 5 4 3 Apg6 coiled-coil region ERM PF00769.19 PVD34341.1 - 0.00028 20.8 25.0 0.0021 17.9 8.2 3.8 2 1 1 3 3 3 2 Ezrin/radixin/moesin family zf-B_box PF00643.24 PVD34341.1 - 0.00036 20.6 8.8 0.00036 20.6 8.8 2.8 3 0 0 3 3 2 1 B-box zinc finger zf-RING_5 PF14634.6 PVD34341.1 - 0.00049 20.0 11.6 0.00049 20.0 11.6 3.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD34341.1 - 0.001 19.3 10.4 0.001 19.3 10.4 3.1 2 1 0 2 2 2 1 Ring finger domain Baculo_PEP_C PF04513.12 PVD34341.1 - 0.0016 18.5 19.6 0.079 13.0 0.1 5.1 2 1 2 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.6 PVD34341.1 - 0.0033 17.5 47.2 0.056 13.5 8.9 5.2 2 1 2 4 4 4 3 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 PVD34341.1 - 0.0035 17.4 20.5 0.12 12.5 0.2 5.7 5 0 0 5 5 5 1 bZIP transcription factor zf-C3HC4 PF00097.25 PVD34341.1 - 0.004 17.0 9.0 0.004 17.0 9.0 3.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) GAS PF13851.6 PVD34341.1 - 0.0052 16.2 5.7 0.0052 16.2 5.7 4.9 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding zf-RING_11 PF17123.5 PVD34341.1 - 0.0088 15.8 4.9 0.038 13.8 4.9 2.2 1 0 0 1 1 1 1 RING-like zinc finger PI_PP_I PF18363.1 PVD34341.1 - 0.019 15.1 13.4 3.4 7.9 0.2 5.6 1 1 3 6 6 6 0 Phosphoinositide phosphatase insertion domain Fez1 PF06818.15 PVD34341.1 - 0.022 15.2 47.8 0.079 13.4 8.5 5.0 2 1 3 5 5 5 0 Fez1 APC_N_CC PF16689.5 PVD34341.1 - 0.041 13.9 0.1 0.041 13.9 0.1 4.7 4 0 0 4 4 3 0 Coiled-coil N-terminus of APC, dimerisation domain Golgin_A5 PF09787.9 PVD34341.1 - 0.044 13.3 49.3 0.12 11.9 8.0 4.2 2 1 2 4 4 4 0 Golgin subfamily A member 5 PA-IL PF07828.12 PVD34341.1 - 0.053 13.5 0.0 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 PA-IL-like protein Spc7 PF08317.11 PVD34341.1 - 0.096 11.6 50.2 0.0063 15.4 6.7 4.2 2 1 2 4 4 4 0 Spc7 kinetochore protein JIP_LZII PF16471.5 PVD34341.1 - 0.11 12.6 0.2 0.11 12.6 0.2 7.9 4 3 3 9 9 8 0 JNK-interacting protein leucine zipper II Bromodomain PF00439.25 PVD34341.1 - 0.11 12.5 0.0 28 4.9 0.0 2.9 2 0 0 2 2 2 0 Bromodomain Vac_Fusion PF02346.16 PVD34341.1 - 0.14 11.8 1.8 25 4.6 0.1 3.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 bZIP_2 PF07716.15 PVD34341.1 - 0.18 11.9 10.5 2.5 8.3 0.1 6.0 6 0 0 6 6 6 0 Basic region leucine zipper FlaC_arch PF05377.11 PVD34341.1 - 0.18 12.2 22.5 1.7 9.1 0.6 6.6 4 1 4 8 8 7 0 Flagella accessory protein C (FlaC) WEMBL PF05701.11 PVD34341.1 - 0.43 9.2 31.1 0.035 12.8 3.4 4.1 2 1 2 4 4 4 0 Weak chloroplast movement under blue light Hemerythrin PF01814.23 PVD34341.1 - 0.54 10.9 14.2 2 9.0 0.1 4.6 4 1 0 4 4 4 0 Hemerythrin HHE cation binding domain ZapB PF06005.12 PVD34341.1 - 0.58 10.6 43.0 0.18 12.3 2.3 6.1 5 3 1 6 6 5 0 Cell division protein ZapB Filament PF00038.21 PVD34341.1 - 0.83 9.2 41.2 0.01 15.5 6.1 4.6 2 1 1 4 4 4 0 Intermediate filament protein BLOC1_2 PF10046.9 PVD34341.1 - 1.4 9.3 22.9 1.9 8.8 1.2 5.2 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 PVD34341.1 - 3.5 7.7 51.5 0.31 11.1 3.3 6.3 2 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 PVD34341.1 - 4.6 5.3 36.8 0.32 9.1 3.2 4.5 2 1 3 5 5 5 0 Septation ring formation regulator, EzrA MCC-bdg_PDZ PF10506.9 PVD34341.1 - 6.6 6.8 20.1 1.6 8.8 2.7 4.0 4 0 0 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DZR PF12773.7 PVD34341.1 - 7 6.8 10.5 4.7e+02 0.9 10.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon DUF1664 PF07889.12 PVD34341.1 - 8.1 6.5 35.6 4.1 7.4 1.9 6.4 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 PVD34341.1 - 8.8 6.6 23.2 18 5.6 3.3 5.3 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Sulfotransfer_2 PF03567.14 PVD34342.1 - 2.4e-29 103.0 7.5 8.2e-27 94.7 4.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family BCD PF15461.6 PVD34342.1 - 0.09 12.3 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase GATase_5 PF13507.6 PVD34343.1 - 6e-99 330.4 0.0 1.2e-98 329.4 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 PVD34343.1 - 7.1e-35 120.4 2.7 4.4e-18 65.9 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 PVD34343.1 - 1.8e-15 56.9 0.0 3.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 PVD34343.1 - 3.1e-11 43.7 0.0 9.2e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Herpes_gp2 PF05955.11 PVD34344.1 - 0.02 14.4 0.0 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 LRR_6 PF13516.6 PVD34346.1 - 2.1e-09 36.7 9.9 0.04 14.0 0.2 5.2 6 0 0 6 6 6 3 Leucine Rich repeat EF-hand_7 PF13499.6 PVD34346.1 - 2.2e-06 28.0 1.0 2.2e-06 28.0 1.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair LRR_8 PF13855.6 PVD34346.1 - 1.4e-05 24.7 9.7 0.0075 16.0 2.4 4.0 2 1 0 2 2 2 2 Leucine rich repeat EF-hand_8 PF13833.6 PVD34346.1 - 5.7e-05 22.9 1.5 0.00019 21.2 0.2 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD34346.1 - 0.00028 20.2 6.0 0.0035 16.8 0.4 2.8 3 0 0 3 3 3 2 EF hand LRR_4 PF12799.7 PVD34346.1 - 0.00029 21.2 7.8 0.63 10.5 0.5 4.5 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 PVD34346.1 - 0.0008 19.2 0.6 0.25 11.4 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain LRR_1 PF00560.33 PVD34346.1 - 0.0035 17.7 2.8 44 5.2 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat EF-hand_5 PF13202.6 PVD34346.1 - 0.02 14.4 0.2 0.02 14.4 0.2 2.2 2 0 0 2 2 2 0 EF hand CH PF00307.31 PVD34347.1 - 3.2e-16 59.5 0.0 5.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 PVD34347.1 - 6.1e-11 41.8 3.3 1.2e-10 40.8 3.3 1.5 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 PVD34347.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain MAM PF00629.23 PVD34349.1 - 2.7e-15 56.6 0.0 2.7e-14 53.4 0.0 2.4 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu Lectin_C PF00059.21 PVD34349.1 - 5.1e-15 56.1 0.1 1.1e-14 55.1 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain IFT57 PF10498.9 PVD34349.1 - 0.00044 19.3 2.0 0.00064 18.8 2.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HOOK PF05622.12 PVD34349.1 - 0.0012 17.1 1.1 0.002 16.4 1.1 1.3 1 0 0 1 1 1 1 HOOK protein DUF4200 PF13863.6 PVD34349.1 - 0.0013 19.2 1.2 0.0019 18.6 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Filament PF00038.21 PVD34349.1 - 0.0018 17.9 6.0 0.0039 16.8 6.0 1.5 1 1 0 1 1 1 1 Intermediate filament protein Fez1 PF06818.15 PVD34349.1 - 0.0021 18.5 1.0 0.0032 17.9 1.0 1.2 1 0 0 1 1 1 1 Fez1 DUF4407 PF14362.6 PVD34349.1 - 0.0025 17.2 3.9 0.0036 16.7 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 PVD34349.1 - 0.0027 17.7 6.5 0.46 10.6 0.1 2.3 1 1 1 2 2 2 2 TolA binding protein trimerisation DUF3584 PF12128.8 PVD34349.1 - 0.0027 15.3 1.7 0.0034 15.0 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 PVD34349.1 - 0.0029 16.5 2.9 0.0051 15.7 2.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein LPP PF04728.13 PVD34349.1 - 0.0036 17.7 6.6 0.011 16.1 1.8 2.8 1 1 2 3 3 3 1 Lipoprotein leucine-zipper She9_MDM33 PF05546.11 PVD34349.1 - 0.0042 16.9 1.1 0.0062 16.4 1.1 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family OmpH PF03938.14 PVD34349.1 - 0.005 17.2 3.3 0.0074 16.6 3.3 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 PVD34349.1 - 0.0053 16.9 1.8 0.0085 16.2 1.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 PVD34349.1 - 0.0064 17.0 4.3 0.01 16.4 4.3 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Zw10 PF06248.13 PVD34349.1 - 0.0071 15.0 2.2 0.0098 14.5 2.2 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 ATG16 PF08614.11 PVD34349.1 - 0.008 16.4 6.5 0.012 15.8 6.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 PVD34349.1 - 0.0083 15.6 3.2 0.012 15.1 3.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 PVD34349.1 - 0.0087 16.5 0.7 4.9 7.7 0.8 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAM76 PF16046.5 PVD34349.1 - 0.0088 15.4 1.4 0.013 14.9 1.4 1.1 1 0 0 1 1 1 1 FAM76 protein Jnk-SapK_ap_N PF09744.9 PVD34349.1 - 0.012 15.8 4.4 0.02 15.1 4.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CCDC144C PF14915.6 PVD34349.1 - 0.013 14.7 4.0 0.018 14.2 4.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF5082 PF16888.5 PVD34349.1 - 0.013 15.8 5.2 0.035 14.4 4.6 2.0 2 1 0 2 2 1 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 PVD34349.1 - 0.015 14.4 4.1 0.027 13.6 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 PVD34349.1 - 0.016 15.7 4.6 0.9 10.0 2.3 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF4618 PF15397.6 PVD34349.1 - 0.016 14.6 3.4 0.5 9.7 1.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 PVD34349.1 - 0.022 15.0 3.0 0.035 14.3 3.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 PVD34349.1 - 0.023 14.9 3.0 0.039 14.1 3.0 1.4 1 0 0 1 1 1 0 Tropomyosin like WEMBL PF05701.11 PVD34349.1 - 0.024 13.4 6.0 0.056 12.1 6.0 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4164 PF13747.6 PVD34349.1 - 0.025 14.8 1.5 0.043 14.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TMF_TATA_bd PF12325.8 PVD34349.1 - 0.03 14.5 7.0 0.094 12.9 7.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Bacillus_HBL PF05791.11 PVD34349.1 - 0.031 14.1 5.7 0.6 9.9 0.6 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Cep57_CLD_2 PF14197.6 PVD34349.1 - 0.039 14.0 4.2 0.22 11.6 4.3 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 PVD34349.1 - 0.042 13.9 8.5 0.076 13.0 7.4 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 PVD34349.1 - 0.042 13.9 6.6 0.065 13.3 6.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4094 PF13334.6 PVD34349.1 - 0.042 14.2 2.3 4.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TPR_MLP1_2 PF07926.12 PVD34349.1 - 0.044 13.8 8.8 0.46 10.6 6.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 PVD34349.1 - 0.047 13.7 6.3 0.59 10.1 2.3 2.2 1 1 1 2 2 2 0 Laminin Domain II DHR10 PF18595.1 PVD34349.1 - 0.055 13.5 4.1 0.082 13.0 4.1 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF812 PF05667.11 PVD34349.1 - 0.058 12.3 5.3 0.26 10.1 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 PVD34349.1 - 0.06 13.6 6.0 0.51 10.6 1.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 PVD34349.1 - 0.066 13.2 7.2 1.1 9.3 2.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.10 PVD34349.1 - 0.083 13.3 4.2 0.5 10.7 2.9 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Uso1_p115_C PF04871.13 PVD34349.1 - 0.088 13.2 5.4 2 8.8 5.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2203 PF09969.9 PVD34349.1 - 0.095 13.4 0.7 0.19 12.4 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HALZ PF02183.18 PVD34349.1 - 0.1 12.8 0.3 0.4 10.9 0.1 2.0 2 0 0 2 2 1 0 Homeobox associated leucine zipper DUF4699 PF15770.5 PVD34349.1 - 0.14 11.9 2.9 0.21 11.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) CLZ PF16526.5 PVD34349.1 - 0.15 12.4 4.8 2.1 8.7 0.1 2.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Chordopox_A33R PF05966.12 PVD34349.1 - 0.16 11.3 1.1 0.5 9.6 0.0 2.4 4 0 0 4 4 1 0 Chordopoxvirus A33R protein Syntaxin_2 PF14523.6 PVD34349.1 - 0.17 12.2 7.5 3.1 8.2 7.6 2.2 1 1 0 1 1 1 0 Syntaxin-like protein Lectin_N PF03954.14 PVD34349.1 - 0.18 11.5 7.3 0.36 10.6 7.3 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 PVD34349.1 - 0.19 11.8 4.3 0.66 10.0 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 PVD34349.1 - 0.21 11.7 6.6 0.34 11.0 6.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 PVD34349.1 - 0.21 11.8 2.9 6.4 7.1 0.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Alanine_zipper PF11839.8 PVD34349.1 - 0.22 11.9 1.7 0.87 10.0 0.4 2.2 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF4201 PF13870.6 PVD34349.1 - 0.23 11.2 4.3 0.45 10.2 2.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Prominin PF05478.11 PVD34349.1 - 0.29 9.0 2.8 0.4 8.6 2.8 1.1 1 0 0 1 1 1 0 Prominin RasGAP_C PF03836.15 PVD34349.1 - 0.39 10.9 4.7 13 6.0 1.8 2.3 1 1 1 2 2 2 0 RasGAP C-terminus Baculo_PEP_C PF04513.12 PVD34349.1 - 0.6 10.1 9.3 1.7 8.7 9.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 PVD34349.1 - 0.63 9.6 5.0 0.11 12.1 1.5 1.4 2 0 0 2 2 1 0 Exonuclease VII, large subunit CHDCT2 PF08074.11 PVD34349.1 - 1 9.5 2.9 20 5.3 0.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain CENP-H PF05837.12 PVD34349.1 - 1 9.8 7.1 1.3 9.4 6.3 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 PVD34349.1 - 1 10.3 5.2 1.9 9.4 5.2 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF148 PF02520.17 PVD34349.1 - 1.1 9.4 5.4 4.1 7.6 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF148 MscS_porin PF12795.7 PVD34349.1 - 1.1 8.8 12.8 5.4 6.5 12.8 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain TMPIT PF07851.13 PVD34349.1 - 1.2 8.3 5.6 5.2 6.2 5.7 1.8 1 1 0 1 1 1 0 TMPIT-like protein FliJ PF02050.16 PVD34349.1 - 1.5 9.1 7.2 6.2 7.1 5.4 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein SlyX PF04102.12 PVD34349.1 - 4.4 8.0 8.1 9 7.0 0.4 2.6 1 1 1 2 2 2 0 SlyX YlqD PF11068.8 PVD34349.1 - 7.9 6.9 9.2 20 5.6 9.0 1.6 1 1 0 1 1 1 0 YlqD protein IBR PF01485.21 PVD34350.1 - 1.1e-15 57.6 16.7 1e-10 41.7 3.2 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 PVD34350.1 - 8.2e-07 29.3 0.6 0.0023 18.2 0.1 2.6 1 1 1 2 2 2 2 RWD domain zinc_ribbon_2 PF13240.6 PVD34350.1 - 0.047 13.4 0.2 0.047 13.4 0.2 5.0 7 0 0 7 7 7 0 zinc-ribbon domain DUF1373 PF07117.11 PVD34350.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) RWD PF05773.22 PVD34351.1 - 1.3e-22 80.2 0.4 4.8e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 RWD domain IBR PF01485.21 PVD34351.1 - 1.4e-16 60.5 16.5 2e-13 50.4 1.8 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 PVD34351.1 - 0.0021 18.0 8.7 0.0021 18.0 8.7 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-ribbon_3 PF13248.6 PVD34351.1 - 0.0038 16.6 3.1 0.076 12.4 0.1 3.8 3 0 0 3 3 3 1 zinc-ribbon domain zf-C3HC4 PF00097.25 PVD34351.1 - 0.0047 16.8 8.7 0.0047 16.8 8.7 4.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD34351.1 - 0.0047 17.2 11.2 0.0047 17.2 11.2 4.6 3 2 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 PVD34351.1 - 0.012 15.5 12.3 0.012 15.5 12.3 4.0 3 1 1 4 4 4 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 PVD34351.1 - 0.099 12.4 0.1 0.099 12.4 0.1 4.3 5 0 0 5 5 5 0 zinc-ribbon domain Amidohydro_1 PF01979.20 PVD34352.1 - 4.8e-08 32.7 0.0 9.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PVD34352.1 - 0.0028 17.2 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family PKK PF12474.8 PVD34352.1 - 1.1 9.4 14.2 3.7 7.7 8.0 2.4 2 0 0 2 2 2 0 Polo kinase kinase MIEAP PF16026.5 PVD34353.1 - 1e-34 120.5 0.1 1e-34 120.5 0.1 2.2 1 1 1 2 2 2 1 Mitochondria-eating protein TPR_MLP1_2 PF07926.12 PVD34353.1 - 1.2e-05 25.3 9.8 1.2e-05 25.3 9.8 2.6 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 PVD34353.1 - 2.8e-05 24.1 16.5 0.003 17.6 0.7 4.4 3 1 0 3 3 3 2 Basic region leucine zipper TSC22 PF01166.18 PVD34353.1 - 0.00035 20.8 5.5 0.44 10.9 0.5 4.0 2 1 1 3 3 3 1 TSC-22/dip/bun family ATG16 PF08614.11 PVD34353.1 - 0.00087 19.6 8.9 0.00087 19.6 8.9 2.7 3 1 0 3 3 2 1 Autophagy protein 16 (ATG16) WEMBL PF05701.11 PVD34353.1 - 0.00099 17.9 8.7 0.0016 17.2 8.7 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Nnf1 PF03980.14 PVD34353.1 - 0.0013 19.1 3.1 0.0013 19.1 3.1 2.8 3 0 0 3 3 2 1 Nnf1 HALZ PF02183.18 PVD34353.1 - 0.0018 18.5 13.0 0.77 10.0 0.2 4.4 4 0 0 4 4 3 2 Homeobox associated leucine zipper CCDC144C PF14915.6 PVD34353.1 - 0.0032 16.6 7.6 0.0084 15.3 7.6 1.8 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region EzrA PF06160.12 PVD34353.1 - 0.0035 15.6 7.3 0.0071 14.6 7.3 1.5 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 PVD34353.1 - 0.004 17.2 10.2 2.6 8.2 0.8 4.0 2 1 1 3 3 3 1 bZIP transcription factor GAS PF13851.6 PVD34353.1 - 0.004 16.5 11.9 0.004 16.5 11.9 3.0 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 PVD34353.1 - 0.0051 17.1 16.4 2.3 8.6 3.1 3.9 2 2 1 3 3 3 1 Csm1 N-terminal domain KASH_CCD PF14662.6 PVD34353.1 - 0.0065 16.3 16.5 0.038 13.8 8.8 2.9 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF2353 PF09789.9 PVD34353.1 - 0.0079 15.6 9.4 0.018 14.4 9.4 1.5 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 PVD34353.1 - 0.0099 15.9 6.9 0.0099 15.9 6.9 3.1 2 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.6 PVD34353.1 - 0.015 14.9 11.7 0.045 13.3 11.7 1.8 1 1 0 1 1 1 0 Leucine zipper Mto2_bdg PF12808.7 PVD34353.1 - 0.026 14.8 6.9 2.5 8.4 0.3 3.5 3 1 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Rootletin PF15035.6 PVD34353.1 - 0.033 14.2 12.6 0.072 13.1 10.1 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SHE3 PF17078.5 PVD34353.1 - 0.041 13.6 11.5 0.43 10.3 11.9 2.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Herpes_BLRF2 PF05812.12 PVD34353.1 - 0.059 13.5 14.9 1.5 8.9 0.5 4.4 2 1 2 4 4 4 0 Herpesvirus BLRF2 protein APG6_N PF17675.1 PVD34353.1 - 0.06 13.9 15.3 0.28 11.7 15.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region IFT57 PF10498.9 PVD34353.1 - 0.062 12.3 8.0 0.16 10.9 8.0 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 PVD34353.1 - 0.083 13.3 10.3 1.6 9.2 0.6 4.8 5 1 1 6 6 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 PVD34353.1 - 0.097 12.0 11.8 0.026 13.8 8.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 PVD34353.1 - 0.13 11.9 14.6 1.5 8.5 9.0 3.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF745 PF05335.13 PVD34353.1 - 0.19 11.5 12.7 0.054 13.2 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CDPS PF16715.5 PVD34353.1 - 0.2 11.3 7.0 0.17 11.5 5.3 1.7 2 0 0 2 2 1 0 Cyclodipeptide synthase YscO PF07321.12 PVD34353.1 - 0.21 11.6 11.4 0.078 12.9 8.2 2.0 2 0 0 2 2 1 0 Type III secretion protein YscO DUF724 PF05266.14 PVD34353.1 - 0.25 11.2 10.2 0.064 13.1 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CP12 PF02672.15 PVD34353.1 - 0.28 12.0 4.5 0.94 10.3 1.8 3.0 2 2 0 2 2 2 0 CP12 domain DUF3584 PF12128.8 PVD34353.1 - 0.32 8.5 15.4 0.0082 13.7 9.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF826 PF05696.11 PVD34353.1 - 0.39 10.8 3.4 0.32 11.1 0.5 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF826) FH2 PF02181.23 PVD34353.1 - 0.43 9.6 8.3 0.66 9.0 7.1 2.0 1 1 0 1 1 1 0 Formin Homology 2 Domain DUF4140 PF13600.6 PVD34353.1 - 0.49 10.9 10.8 0.15 12.5 1.8 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 PVD34353.1 - 0.49 10.2 22.7 0.059 13.2 4.9 4.6 3 2 2 5 5 5 0 Septum formation initiator DUF4201 PF13870.6 PVD34353.1 - 0.59 9.9 15.2 8.8 6.0 2.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 PVD34353.1 - 0.72 10.1 19.4 0.22 11.7 6.1 3.3 3 1 1 4 4 2 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 PVD34353.1 - 0.74 7.6 4.3 1.2 7.0 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT_CC PF16559.5 PVD34353.1 - 0.77 9.7 12.7 0.11 12.4 2.3 3.3 4 0 0 4 4 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 PVD34353.1 - 0.81 10.1 9.0 0.63 10.4 4.3 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 5_nucleotid PF05761.14 PVD34353.1 - 0.83 8.5 4.7 1.6 7.5 4.7 1.4 1 0 0 1 1 1 0 5' nucleotidase family Spc7 PF08317.11 PVD34353.1 - 1.2 7.9 15.8 0.22 10.4 11.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 PVD34353.1 - 1.3 8.2 9.1 0.18 11.0 5.0 1.6 2 0 0 2 2 1 0 TMPIT-like protein THOC7 PF05615.13 PVD34353.1 - 1.6 9.0 14.7 5.2 7.4 13.9 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 DivIVA PF05103.13 PVD34353.1 - 1.6 8.8 16.8 0.19 11.8 1.8 3.6 2 2 0 3 3 3 0 DivIVA protein HAUS-augmin3 PF14932.6 PVD34353.1 - 2.4 7.7 14.6 3.7 7.0 12.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 PVD34353.1 - 2.6 8.7 8.0 10 6.8 4.3 3.2 2 1 0 2 2 2 0 SlyX Syntaxin PF00804.25 PVD34353.1 - 2.8 7.5 16.5 0.091 12.4 8.4 2.4 2 1 1 3 3 3 0 Syntaxin YabA PF06156.13 PVD34353.1 - 2.9 8.6 13.9 1.4 9.6 3.3 4.0 1 1 2 3 3 3 0 Initiation control protein YabA ADIP PF11559.8 PVD34353.1 - 2.9 8.0 18.8 0.064 13.4 9.7 2.8 2 1 1 3 3 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 PVD34353.1 - 3.2 6.2 11.3 0.55 8.8 6.8 1.8 1 1 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 PVD34353.1 - 3.7 6.5 14.8 2.9 6.9 13.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 PVD34353.1 - 4.2 7.9 21.6 0.44 11.0 5.3 4.0 4 1 1 5 5 3 0 Cell division protein ZapB BLOC1_2 PF10046.9 PVD34353.1 - 4.2 7.7 12.4 5.9 7.3 2.5 3.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 PVD34353.1 - 5.5 6.8 17.2 6.1 6.6 12.2 3.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.11 PVD34353.1 - 6.3 4.6 14.4 0.073 11.0 3.8 2.6 3 0 0 3 3 3 0 Prominin DUF1664 PF07889.12 PVD34353.1 - 6.9 6.7 8.0 7.8 6.6 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 PVD34353.1 - 7.1 7.6 19.3 5.6 7.9 0.8 3.7 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain GrpE PF01025.19 PVD34353.1 - 7.3 6.2 13.1 1.4 8.6 7.5 2.6 2 1 0 2 2 2 0 GrpE Fez1 PF06818.15 PVD34353.1 - 7.9 6.9 20.4 0.29 11.6 11.5 2.4 2 1 0 2 2 2 0 Fez1 UPF0242 PF06785.11 PVD34353.1 - 9 6.4 15.5 2.4e+02 1.7 15.4 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CHD5 PF04420.14 PVD34353.1 - 9 6.1 15.3 1.8 8.4 8.9 2.3 2 0 0 2 2 2 0 CHD5-like protein DUF3810 PF12725.7 PVD34353.1 - 9.2 5.5 8.0 4.6 6.5 4.0 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3810) TFIIA PF03153.13 PVD34354.1 - 0.01 15.9 14.6 0.012 15.6 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 PVD34354.1 - 0.32 10.9 6.4 0.4 10.6 6.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.22 PVD34354.1 - 2.8 7.1 4.3 3.5 6.7 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HemX PF04375.14 PVD34354.1 - 3.2 6.9 11.9 5.2 6.3 11.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FAM181 PF15238.6 PVD34355.1 - 4e-05 23.6 0.4 6.5e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 FAM181 DUF4288 PF14119.6 PVD34355.1 - 0.16 12.4 0.0 20 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) HECT PF00632.25 PVD34356.1 - 1.9e-89 300.2 0.1 2.7e-89 299.7 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3136 PF11334.8 PVD34356.1 - 0.15 11.9 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) zf-NF-X1 PF01422.17 PVD34357.1 - 3e-09 36.8 79.8 4e-05 23.6 14.5 17.7 19 0 0 19 19 19 11 NF-X1 type zinc finger Thymosin PF01290.20 PVD34358.1 - 6.2e-51 169.9 28.1 5.7e-11 42.0 2.0 5.1 5 0 0 5 5 5 5 Thymosin beta-4 family WH2 PF02205.20 PVD34358.1 - 0.00021 21.0 1.6 2 8.3 0.0 4.7 5 0 0 5 5 5 2 WH2 motif Anthrax-tox_M PF09156.10 PVD34358.1 - 0.014 14.8 3.9 0.012 14.9 2.7 1.4 1 1 0 1 1 1 0 Anthrax toxin lethal factor, middle domain DUF4522 PF15022.6 PVD34358.1 - 0.019 15.2 8.3 1.8 8.9 0.1 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF4522) DicB PF05358.11 PVD34358.1 - 0.039 14.1 2.1 31 4.8 0.0 4.0 4 0 0 4 4 4 0 DicB protein Noggin PF05806.12 PVD34358.1 - 0.2 11.5 5.0 0.25 11.3 1.9 1.9 1 1 1 2 2 2 0 Noggin ARA70 PF12489.8 PVD34358.1 - 2.4 8.4 6.7 1.1 9.4 3.6 1.9 1 1 0 1 1 1 0 Nuclear coactivator Glyco_transf_41 PF13844.6 PVD34359.1 - 1e-173 578.2 0.4 8.4e-168 558.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 PVD34359.1 - 2.8e-95 308.6 30.8 1.2e-08 34.4 0.3 13.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 PVD34359.1 - 2.6e-91 299.1 37.0 7.2e-12 44.8 1.0 13.0 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 PVD34359.1 - 2.9e-73 236.2 26.9 8.5e-07 28.6 0.4 12.7 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 PVD34359.1 - 5.8e-69 223.6 31.7 3.2e-08 33.4 0.2 12.8 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_8 PF13181.6 PVD34359.1 - 6.2e-66 213.2 16.8 6.7e-06 25.9 0.0 13.3 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_12 PF13424.6 PVD34359.1 - 1.4e-48 163.0 28.2 5.5e-11 42.6 0.6 9.0 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 PVD34359.1 - 5.3e-44 145.1 13.4 0.00012 22.6 0.0 12.4 5 3 7 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 PVD34359.1 - 1.3e-40 137.7 9.1 2.8e-07 31.1 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 PVD34359.1 - 2.7e-40 136.7 22.0 8e-07 29.5 0.4 9.0 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 PVD34359.1 - 4.9e-39 129.5 18.3 7.7e-05 22.5 0.0 12.9 13 1 1 14 14 13 8 Tetratricopeptide repeat TPR_10 PF13374.6 PVD34359.1 - 1.1e-36 123.7 45.2 9.3e-07 28.5 0.5 12.6 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_9 PF13371.6 PVD34359.1 - 3.2e-18 65.7 7.3 0.0062 16.6 0.0 6.7 4 2 2 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 PVD34359.1 - 6.6e-16 57.8 11.8 0.47 11.2 0.0 10.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 PVD34359.1 - 9.2e-14 50.6 9.6 1.5 9.7 0.1 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat NARP1 PF12569.8 PVD34359.1 - 4.7e-13 48.9 10.1 0.00096 18.2 0.1 6.0 2 1 6 8 8 8 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 PVD34359.1 - 5.3e-13 49.0 11.4 0.00015 21.3 0.3 4.6 2 2 2 4 4 4 4 MalT-like TPR region TPR_15 PF13429.6 PVD34359.1 - 1.1e-09 38.0 10.9 0.00042 19.6 1.0 5.9 3 2 1 4 4 3 3 Tetratricopeptide repeat FAT PF02259.23 PVD34359.1 - 2.6e-08 33.5 1.8 0.029 13.6 0.2 6.4 3 2 1 4 4 4 1 FAT domain TPR_21 PF09976.9 PVD34359.1 - 5.6e-07 29.5 11.0 0.31 10.7 0.3 5.2 3 2 1 4 4 4 3 Tetratricopeptide repeat-like domain EST1_DNA_bind PF10373.9 PVD34359.1 - 1.5e-05 24.7 12.7 0.11 11.9 0.1 4.6 4 1 0 4 4 4 3 Est1 DNA/RNA binding domain BTAD PF03704.17 PVD34359.1 - 0.00038 20.9 12.2 2.7 8.4 0.6 5.3 2 2 3 5 5 5 2 Bacterial transcriptional activator domain SNAP PF14938.6 PVD34359.1 - 0.00057 19.4 16.0 0.054 12.9 2.9 4.8 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 PVD34359.1 - 0.0023 17.9 30.8 4.5 7.4 0.1 9.1 10 0 0 10 10 8 1 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 PVD34359.1 - 0.0028 17.6 8.2 35 4.4 0.0 6.7 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 PPR PF01535.20 PVD34359.1 - 0.0073 16.5 4.0 37 4.9 0.0 6.9 8 0 0 8 8 7 0 PPR repeat ANAPC3 PF12895.7 PVD34359.1 - 0.013 15.7 19.4 0.014 15.6 0.4 5.7 3 2 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 PVD34359.1 - 0.016 14.7 6.5 3.2 7.3 0.0 5.5 6 1 1 7 7 6 0 SHNi-TPR Fis1_TPR_C PF14853.6 PVD34359.1 - 0.019 15.0 0.1 0.16 12.1 0.0 2.7 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 PVD34359.1 - 0.021 15.2 15.8 0.78 10.1 0.4 6.8 4 2 4 9 9 9 0 Tetratricopeptide repeat RPN7 PF10602.9 PVD34359.1 - 0.027 14.2 9.3 8.5 6.0 0.2 6.2 2 2 4 7 7 7 0 26S proteasome subunit RPN7 Nitrophorin PF02087.15 PVD34359.1 - 0.12 12.4 0.2 3.5 7.6 0.1 2.8 1 1 1 2 2 2 0 Nitrophorin DUF627 PF04781.12 PVD34359.1 - 0.21 11.6 7.0 33 4.6 0.0 5.5 3 1 2 5 5 5 0 Protein of unknown function (DUF627) TPR_3 PF07720.12 PVD34359.1 - 0.6 10.2 15.0 0.63 10.1 0.0 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PVD34359.1 - 3.2 8.2 7.5 3.5 8.1 0.1 3.7 4 1 0 4 4 2 0 Alkyl sulfatase dimerisation Plk4_PB1 PF18190.1 PVD34360.1 - 1.6e-28 99.0 0.0 3.6e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 PVD34360.1 - 2.7e-26 92.4 0.0 9.9e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 POLO_box PF00659.18 PVD34360.1 - 7.8e-05 22.8 0.0 0.00034 20.7 0.0 2.1 2 0 0 2 2 2 1 POLO box duplicated region DUF4520 PF15016.6 PVD34360.1 - 0.083 13.0 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) SPOB_ab PF14682.6 PVD34360.1 - 0.19 11.8 0.5 5 7.3 0.0 2.8 3 0 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal Plk4_PB1 PF18190.1 PVD34361.1 - 4.8e-36 123.2 0.1 1.1e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 PVD34361.1 - 6.3e-32 110.5 0.1 1.3e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 DUF4455 PF14643.6 PVD34361.1 - 0.034 12.8 0.1 0.047 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Pkinase PF00069.25 PVD34362.1 - 2.7e-74 249.9 0.1 3.4e-74 249.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34362.1 - 5.1e-45 153.8 0.0 7.5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD34362.1 - 7.3e-08 31.6 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD34362.1 - 8.5e-07 28.6 0.0 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 PVD34362.1 - 1.3e-05 24.9 6.1 0.00051 19.7 0.2 2.5 2 1 1 3 3 3 2 RIO1 family Haspin_kinase PF12330.8 PVD34362.1 - 8.6e-05 21.6 0.9 0.00017 20.7 0.9 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD34362.1 - 0.023 14.6 1.1 0.067 13.1 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 PVD34362.1 - 0.064 12.9 0.6 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 PVD34362.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Plk4_PB2 PF18409.1 PVD34363.1 - 4.3e-35 120.7 0.6 3.7e-33 114.5 0.2 2.6 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 PVD34363.1 - 1.6e-25 89.3 0.1 8.1e-25 87.1 0.0 2.2 3 0 0 3 3 3 1 Polo-like Kinase 4 Polo Box 1 POLO_box PF00659.18 PVD34363.1 - 1.7e-08 34.5 0.0 2.2e-07 30.9 0.0 2.8 3 0 0 3 3 3 1 POLO box duplicated region AXH PF08517.12 PVD34363.1 - 0.0017 18.9 0.1 0.007 16.9 0.1 2.1 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ELP6 PF09807.9 PVD34363.1 - 0.027 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Elongation complex protein 6 PAS_7 PF12860.7 PVD34363.1 - 0.029 14.5 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold DUF4520 PF15016.6 PVD34363.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) CactinC_cactus PF09732.9 PVD34363.1 - 0.053 13.5 0.4 37 4.3 0.0 3.1 3 0 0 3 3 3 0 Cactus-binding C-terminus of cactin protein ATF7IP_BD PF16788.5 PVD34363.1 - 3.1 7.9 9.0 0.43 10.7 3.7 2.1 2 0 0 2 2 2 0 ATF-interacting protein binding domain Pkinase PF00069.25 PVD34364.1 - 8.6e-69 231.8 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34364.1 - 2.4e-44 151.6 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD34364.1 - 5.6e-10 38.6 0.0 1.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PVD34364.1 - 4.6e-06 26.2 0.0 1.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PVD34364.1 - 0.00022 20.9 4.0 0.0019 17.8 4.0 2.0 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PVD34364.1 - 0.0008 19.1 0.7 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Plk4_PB1 PF18190.1 PVD34364.1 - 0.0027 17.9 0.5 0.0075 16.4 0.2 1.9 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 APH PF01636.23 PVD34364.1 - 0.0031 17.5 0.1 0.027 14.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD34364.1 - 0.0086 15.1 3.5 0.014 14.4 0.6 2.3 2 1 0 2 2 2 1 Haspin like kinase domain RNaseH_like PF04308.12 PVD34364.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease H-like HSP70 PF00012.20 PVD34365.1 - 1.8e-146 488.8 7.8 4.2e-92 309.3 3.6 2.3 1 1 1 2 2 2 2 Hsp70 protein Apolipoprotein PF01442.18 PVD34365.1 - 0.0031 17.4 1.2 0.26 11.1 1.4 2.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain MreB_Mbl PF06723.13 PVD34365.1 - 0.033 13.0 0.1 0.44 9.3 0.1 2.2 1 1 1 2 2 2 0 MreB/Mbl protein DUF4263 PF14082.6 PVD34365.1 - 0.75 10.0 4.2 0.49 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) UPF0016 PF01169.19 PVD34366.1 - 2.2e-41 140.0 24.5 2.2e-21 75.9 4.5 3.0 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Aa_trans PF01490.18 PVD34366.1 - 1.5e-36 126.0 20.4 2.1e-35 122.2 6.0 3.3 3 0 0 3 3 3 2 Transmembrane amino acid transporter protein SpoIIIAH PF12685.7 PVD34366.1 - 0.012 15.4 0.1 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Adaptin_binding PF10199.9 PVD34366.1 - 0.017 15.8 1.6 0.025 15.2 0.0 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4230 PF14014.6 PVD34366.1 - 0.09 13.0 2.2 0.17 12.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) TMEM208_SND2 PF05620.11 PVD34366.1 - 0.1 12.4 3.8 0.14 11.9 0.0 2.7 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 ANF_receptor PF01094.28 PVD34367.1 - 1.7e-41 142.5 0.0 4.2e-40 137.9 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD34367.1 - 3e-15 56.6 1.9 5.7e-15 55.7 1.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 PVD34367.1 - 2.1e-08 34.2 0.0 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein UQ_con PF00179.26 PVD34368.1 - 4.2e-52 175.5 0.0 4.8e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PVD34368.1 - 0.0017 18.6 0.1 0.0028 17.9 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 PVD34368.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B bZIP_2 PF07716.15 PVD34368.1 - 0.062 13.4 1.3 0.093 12.8 1.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper UFC1 PF08694.11 PVD34368.1 - 0.21 11.2 0.3 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_C78 PF07910.13 PVD34369.1 - 3.1e-44 151.0 0.1 4.7e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Sp38 PF07354.12 PVD34372.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Galactosyl_T PF01762.21 PVD34374.1 - 2.5e-41 141.6 0.2 3.8e-41 141.1 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 PVD34375.1 - 1e-34 120.1 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Cnd1 PF12717.7 PVD34376.1 - 0.00037 20.6 13.4 0.0068 16.5 0.3 5.2 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Peptidase_M85 PF13678.6 PVD34376.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease AAA_33 PF13671.6 PVD34377.1 - 3.7e-15 56.3 0.0 1.5e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PVD34377.1 - 0.00028 20.2 0.1 0.0024 17.2 0.1 2.2 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 PVD34377.1 - 0.00037 20.0 0.2 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 PVD34377.1 - 0.0096 16.5 0.4 0.081 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 PVD34377.1 - 0.055 12.8 0.0 0.75 9.1 0.0 2.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase ATPase_2 PF01637.18 PVD34377.1 - 0.055 13.4 0.3 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 PVD34377.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_like PF09279.11 PVD34377.1 - 0.13 12.8 0.7 0.64 10.5 0.7 2.2 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like S36_mt PF10937.8 PVD34377.1 - 0.79 11.3 4.9 0.71 11.5 1.5 2.7 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial DUF1771 PF08590.10 PVD34378.1 - 9.3e-20 70.8 5.1 9.3e-20 70.8 5.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 PVD34378.1 - 1e-11 45.0 0.1 6.5e-11 42.4 0.1 2.4 2 0 0 2 2 2 1 Smr domain CUE PF02845.16 PVD34378.1 - 1.4e-05 24.7 0.1 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 CUE domain DMA PF03474.14 PVD34378.1 - 0.0012 18.4 0.1 0.039 13.5 0.0 3.0 3 0 0 3 3 3 1 DMRTA motif Glycos_transf_3 PF00591.21 PVD34378.1 - 0.077 12.6 2.8 5.3 6.5 0.4 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain TFIID-31kDa PF02291.15 PVD34379.1 - 1.6e-46 157.4 0.1 2.2e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 PVD34379.1 - 2.5e-07 31.0 0.1 4.3e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PVD34379.1 - 3.4e-05 23.9 0.1 8.7e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 PVD34379.1 - 0.00049 20.1 0.0 0.00081 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 PVD34379.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_32 PF13654.6 PVD34379.1 - 0.0038 16.1 0.0 0.0048 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CBFD_NFYB_HMF PF00808.23 PVD34379.1 - 0.0063 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIP49_C PF17856.1 PVD34379.1 - 0.035 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 AAA-lid domain Hs1pro-1_N PF07231.12 PVD34379.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Hs1pro-1 N-terminus Med16 PF11635.8 PVD34380.1 - 3.5e-49 167.4 0.0 6.5e-49 166.6 0.0 1.4 1 1 0 1 1 1 1 Mediator complex subunit 16 PDGF PF00341.17 PVD34381.1 - 1.1e-13 51.3 1.3 1.1e-13 51.3 1.3 3.0 1 1 2 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.14 PVD34381.1 - 0.0012 19.1 2.4 0.0012 19.1 2.4 5.2 5 0 0 5 5 5 2 CXCXC repeat SSP160 PF06933.11 PVD34381.1 - 0.0033 15.7 5.4 0.0047 15.2 5.4 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 PVD34381.1 - 0.48 10.4 8.1 1.3 9.0 8.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 PVD34381.1 - 1.1 7.2 3.1 1.5 6.8 3.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 PVD34381.1 - 3.6 7.6 17.7 8.5 6.4 17.6 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Cyclin_N PF00134.23 PVD34383.1 - 5.4e-11 42.3 0.1 1.2e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box_4 PF15966.5 PVD34383.1 - 0.14 12.0 4.7 0.32 10.9 2.4 2.1 1 1 1 2 2 2 0 F-box Pkinase PF00069.25 PVD34385.1 - 2.6e-56 190.9 1.0 1.3e-55 188.6 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34385.1 - 1.5e-25 90.0 0.0 6e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD34385.1 - 0.005 15.8 0.1 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain La PF05383.17 PVD34386.1 - 7.5e-23 80.3 0.5 1.6e-22 79.3 0.2 1.8 2 0 0 2 2 2 1 La domain DUF2048 PF09752.9 PVD34387.1 - 7.1e-34 117.4 0.0 8e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 PVD34387.1 - 0.0094 15.6 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Maf PF02545.14 PVD34388.1 - 2.6e-38 131.5 0.0 2.9e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NHL PF01436.21 PVD34389.1 - 3.1e-36 121.6 11.9 2.3e-08 33.7 0.1 5.7 5 0 0 5 5 5 5 NHL repeat zf-B_box PF00643.24 PVD34389.1 - 4.5e-09 36.3 5.8 4.5e-09 36.3 5.8 4.2 4 2 1 5 5 4 2 B-box zinc finger SGL PF08450.12 PVD34389.1 - 9.6e-07 28.6 0.2 0.25 10.9 0.1 3.3 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PVD34389.1 - 2e-06 27.2 13.4 2e-05 23.9 0.4 4.2 4 1 1 5 5 5 2 6-bladed beta-propeller zf-RING_UBOX PF13445.6 PVD34389.1 - 4.9e-05 23.3 10.3 4.9e-05 23.3 10.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD34389.1 - 0.00012 21.8 11.6 0.00012 21.8 11.6 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD34389.1 - 0.00019 21.3 11.3 0.00019 21.3 11.3 3.6 2 1 1 3 3 2 1 zinc-RING finger domain zf-UBR PF02207.20 PVD34389.1 - 0.0042 17.2 5.6 0.0042 17.2 5.6 4.2 1 1 2 3 3 1 1 Putative zinc finger in N-recognin (UBR box) Phage_holin_6_1 PF09682.10 PVD34389.1 - 0.083 13.3 0.6 0.18 12.3 0.6 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) zf-C2H2_10 PF16588.5 PVD34389.1 - 0.084 12.6 0.3 0.084 12.6 0.3 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger FlgD_ig PF13860.6 PVD34389.1 - 0.093 12.6 0.6 17 5.4 0.0 3.0 3 0 0 3 3 3 0 FlgD Ig-like domain CHU_C PF13585.6 PVD34389.1 - 0.15 12.1 3.1 7.4 6.7 0.0 4.1 4 0 0 4 4 4 0 C-terminal domain of CHU protein family LRR_6 PF13516.6 PVD34390.1 - 8.4e-13 47.3 9.0 0.036 14.1 0.0 7.0 7 0 0 7 7 7 3 Leucine Rich repeat EF-hand_1 PF00036.32 PVD34390.1 - 3.6e-06 26.1 3.9 2.1e-05 23.7 1.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PVD34390.1 - 4.1e-06 27.1 0.2 2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD34390.1 - 2.7e-05 23.4 0.8 0.00012 21.4 0.8 2.1 1 0 0 1 1 1 1 EF hand LRR_1 PF00560.33 PVD34390.1 - 0.00017 21.6 5.0 25 5.9 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat EF-hand_6 PF13405.6 PVD34390.1 - 0.0015 18.3 3.5 0.029 14.3 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 PVD34390.1 - 0.0027 17.5 0.1 0.0084 15.9 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 PVD34390.1 - 0.1 13.1 8.9 18 5.9 3.6 4.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) zf-Tim10_DDP PF02953.15 PVD34391.1 - 4.9e-13 48.5 3.0 1e-12 47.5 3.0 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Alpha-amylase PF00128.24 PVD34392.1 - 1.6e-23 83.8 0.0 1e-10 41.8 0.0 3.9 4 0 0 4 4 4 2 Alpha amylase, catalytic domain ALS_ss_C PF10369.9 PVD34392.1 - 0.025 14.8 0.1 3.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Small subunit of acetolactate synthase Mltc_N PF11873.8 PVD34392.1 - 0.045 13.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain ShK PF01549.24 PVD34392.1 - 0.19 12.3 7.1 0.07 13.7 3.5 2.3 2 0 0 2 2 2 0 ShK domain-like Epimerase PF01370.21 PVD34393.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sulfatase PF00884.23 PVD34394.1 - 4.3e-34 118.3 0.2 3.5e-31 108.7 0.2 2.2 2 0 0 2 2 2 2 Sulfatase Sulfatase PF00884.23 PVD34395.1 - 5.1e-38 131.2 0.0 1e-37 130.2 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD34395.1 - 0.00032 20.4 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 PVD34395.1 - 0.014 15.7 0.1 0.042 14.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 PVD34395.1 - 0.034 12.8 0.0 0.08 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD34396.1 - 4.8e-31 108.3 0.0 1.1e-30 107.2 0.0 1.6 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD34396.1 - 0.0029 17.9 0.3 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 PVD34396.1 - 0.0041 16.8 0.1 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 PVD34396.1 - 0.014 14.0 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD34398.1 - 7.2e-49 166.8 0.0 8.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD34398.1 - 7.3e-11 42.2 0.1 6.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase An_peroxidase PF03098.15 PVD34398.1 - 0.032 12.8 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase Thioredoxin PF00085.20 PVD34399.1 - 7.5e-08 32.3 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 PVD34399.1 - 0.00012 21.2 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin 7tm_1 PF00001.21 PVD34400.1 - 1.1e-35 123.2 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD34400.1 - 5.1e-06 26.0 6.2 7.1e-06 25.6 6.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD34400.1 - 0.9 9.1 5.4 1.4 8.5 5.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx adh_short PF00106.25 PVD34401.1 - 6.3e-58 195.5 0.4 8.1e-58 195.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD34401.1 - 1e-43 149.6 0.3 1.4e-43 149.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD34401.1 - 1.9e-14 54.0 0.4 3.5e-14 53.1 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD34401.1 - 0.00033 20.2 1.0 0.00086 18.8 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PVD34401.1 - 0.00051 20.0 0.3 0.0012 18.8 0.3 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PVD34401.1 - 0.00066 18.9 0.2 0.001 18.2 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 PVD34401.1 - 0.0018 18.1 0.5 0.0038 17.1 0.3 1.6 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 PVD34401.1 - 0.0046 16.9 0.5 0.0072 16.2 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 PVD34401.1 - 0.019 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 PVD34401.1 - 0.033 13.2 0.4 0.19 10.7 0.5 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 PVD34401.1 - 0.05 13.6 0.2 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNaseH_like PF04308.12 PVD34401.1 - 0.071 13.0 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Ribonuclease H-like Wax2_C PF12076.8 PVD34401.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain Pyr_redox_2 PF07992.14 PVD34401.1 - 0.086 12.0 0.1 0.25 10.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 PVD34401.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.12 PVD34402.1 - 5.4e-44 150.3 0.0 8.2e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 PVD34402.1 - 1.9e-22 79.4 0.0 2.9e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 PVD34402.1 - 3.8e-18 65.6 0.0 6.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 PVD34402.1 - 9e-08 31.9 0.0 3.2e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 PVD34402.1 - 1.1e-07 32.7 0.1 3.5e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 PVD34402.1 - 1.4e-06 27.5 0.0 3.2e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PVD34402.1 - 0.00063 19.0 0.1 0.013 14.6 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PVD34402.1 - 0.0098 15.3 0.1 1.2 8.4 0.0 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase AMP-binding PF00501.28 PVD34403.1 - 8.8e-46 156.3 0.0 1.1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DNA_pol_A_exo1 PF01612.20 PVD34404.1 - 2.8e-07 30.4 0.0 6.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LSM14 PF12701.7 PVD34404.1 - 0.016 15.3 1.4 0.078 13.1 0.2 2.8 3 1 0 3 3 3 0 Scd6-like Sm domain LSM PF01423.22 PVD34404.1 - 0.1 12.3 0.1 0.3 10.8 0.1 1.8 1 0 0 1 1 1 0 LSM domain SM-ATX PF14438.6 PVD34404.1 - 0.11 12.6 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF4600 PF15372.6 PVD34405.1 - 2.9e-35 121.5 12.5 2.9e-35 121.5 12.5 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4600) Uso1_p115_C PF04871.13 PVD34405.1 - 0.0084 16.5 16.4 0.041 14.3 6.4 2.3 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 PVD34405.1 - 0.01 15.9 7.5 0.37 10.8 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 PVD34405.1 - 0.013 15.4 10.0 0.13 12.1 0.5 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 GAS PF13851.6 PVD34405.1 - 0.015 14.6 7.9 0.015 14.6 7.9 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 PVD34405.1 - 0.026 14.9 20.3 0.33 11.4 9.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HALZ PF02183.18 PVD34405.1 - 0.034 14.4 7.6 2.7 8.3 0.3 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper MapZ_EC1 PF18041.1 PVD34405.1 - 0.043 14.1 1.3 0.043 14.1 1.3 2.1 3 0 0 3 3 2 0 MapZ extracellular domain 1 DUF713 PF05218.14 PVD34405.1 - 0.05 13.3 5.3 0.049 13.4 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Stn1 PF10451.9 PVD34405.1 - 0.062 12.3 4.2 0.11 11.5 4.2 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF825 PF05695.12 PVD34405.1 - 0.071 10.3 1.5 0.085 10.0 1.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Tropomyosin_1 PF12718.7 PVD34405.1 - 0.075 13.2 17.3 0.47 10.6 2.1 2.3 1 1 1 2 2 2 0 Tropomyosin like ALMT PF11744.8 PVD34405.1 - 0.21 10.4 2.5 0.26 10.1 2.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TMPIT PF07851.13 PVD34405.1 - 0.3 10.3 7.7 0.42 9.8 7.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Imm27 PF15590.6 PVD34405.1 - 0.46 10.3 3.1 12 5.8 0.4 2.7 2 0 0 2 2 2 0 Immunity protein 27 FliJ PF02050.16 PVD34405.1 - 0.48 10.6 18.0 3.2 8.0 4.9 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein T3SSipB PF16535.5 PVD34405.1 - 0.53 10.8 9.1 1.2 9.6 6.8 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF745 PF05335.13 PVD34405.1 - 0.59 9.8 10.6 0.71 9.6 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) BRE1 PF08647.11 PVD34405.1 - 0.8 9.8 11.6 1.9 8.6 0.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 PVD34405.1 - 0.89 8.4 17.9 0.55 9.1 8.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 PVD34405.1 - 0.99 8.9 5.5 1.4 8.4 3.4 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein FH2 PF02181.23 PVD34405.1 - 1 8.4 10.4 1.6 7.8 3.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Fib_alpha PF08702.10 PVD34405.1 - 1.3 9.2 11.1 7.2 6.8 4.3 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2681 PF10883.8 PVD34405.1 - 1.6 9.2 11.5 1.2 9.6 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ADIP PF11559.8 PVD34405.1 - 1.8 8.6 20.1 1 9.4 7.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 PVD34405.1 - 2.2 6.8 9.9 2.9 6.4 8.9 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF5320 PF17253.2 PVD34405.1 - 2.6 9.2 10.4 72 4.5 3.0 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Ax_dynein_light PF10211.9 PVD34405.1 - 2.6 8.0 18.8 5 7.0 3.2 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 PVD34405.1 - 3.6 7.6 17.4 7.5 6.6 15.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 PVD34405.1 - 3.9 7.5 15.3 1.1 9.3 6.6 2.3 1 1 1 2 2 2 0 FlxA-like protein LMBR1 PF04791.16 PVD34405.1 - 4 6.2 7.3 5.2 5.9 7.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RasGAP_C PF03836.15 PVD34405.1 - 4.6 7.4 11.9 44 4.2 11.9 2.1 1 1 0 1 1 1 0 RasGAP C-terminus TBCA PF02970.16 PVD34405.1 - 6.3 7.2 14.3 0.72 10.2 4.1 2.9 3 0 0 3 3 3 0 Tubulin binding cofactor A FlaC_arch PF05377.11 PVD34405.1 - 6.8 7.2 6.2 6.2 7.3 2.6 2.7 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 PVD34405.1 - 7.4 6.1 9.6 3.2 7.3 4.2 2.2 1 1 2 3 3 3 0 fzo-like conserved region Prefoldin_2 PF01920.20 PVD34405.1 - 9.5 6.2 16.5 0.29 11.1 0.9 3.3 1 1 1 2 2 1 0 Prefoldin subunit Cadherin PF00028.17 PVD34407.1 - 6.8e-61 202.7 3.7 7.1e-16 58.4 0.1 7.9 8 0 0 8 8 8 6 Cadherin domain Cadherin_3 PF16184.5 PVD34407.1 - 3.9e-06 26.8 1.6 0.26 11.3 0.0 4.6 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 PVD34407.1 - 0.00083 19.1 0.1 0.36 10.7 0.0 3.7 4 0 0 4 4 4 1 Cadherin-like Shisa PF13908.6 PVD34407.1 - 0.098 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4961 PF16328.5 PVD34411.1 - 0.032 13.5 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) TgMIC1 PF11476.8 PVD34412.1 - 0.088 12.6 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Cadherin PF00028.17 PVD34414.1 - 1.6e-91 300.9 12.5 2.1e-18 66.6 0.2 8.7 7 3 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 PVD34414.1 - 1.4e-15 56.8 1.0 2.5e-10 40.1 0.0 4.6 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 PVD34414.1 - 7.1e-06 26.0 11.1 2.6 8.1 0.1 6.6 7 0 0 7 7 7 2 Cadherin-like SID-1_RNA_chan PF13965.6 PVD34414.1 - 0.011 14.2 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pox_I5 PF04713.12 PVD34414.1 - 0.019 15.0 0.5 0.056 13.5 0.5 1.8 1 0 0 1 1 1 0 Poxvirus protein I5 TMEM154 PF15102.6 PVD34414.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.0 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 PVD34414.1 - 0.031 15.1 1.4 0.045 14.6 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 PVD34414.1 - 0.12 11.9 0.0 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family LST1 PF05083.13 PVD34414.1 - 0.13 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 LST-1 protein Cadherin PF00028.17 PVD34421.1 - 3.1e-107 351.3 10.8 2.3e-22 79.3 0.0 7.6 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 PVD34421.1 - 8.4e-15 54.4 0.1 3.8e-08 33.1 0.0 6.6 7 0 0 7 7 7 1 Cadherin-like TMEM154 PF15102.6 PVD34421.1 - 0.001 19.0 0.1 0.0025 17.7 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_3 PF16184.5 PVD34421.1 - 0.0088 16.0 15.5 4.4 7.4 0.0 6.9 6 1 1 7 7 7 2 Cadherin-like Y_Y_Y PF07495.13 PVD34421.1 - 0.029 14.3 1.2 3.2 7.8 0.0 3.9 3 0 0 3 3 3 0 Y_Y_Y domain Ly49 PF08391.10 PVD34421.1 - 0.14 12.5 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF5527 PF17665.1 PVD34421.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Cadherin_4 PF17803.1 PVD34421.1 - 0.2 12.3 18.4 2.7 8.7 1.0 5.5 4 1 1 5 5 5 0 Bacterial cadherin-like domain DUF4307 PF14155.6 PVD34421.1 - 1.5 8.6 6.6 2.1 8.2 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4307) Big_1 PF02369.16 PVD34421.1 - 5.5 7.1 11.5 5.8 7.0 0.2 4.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) FAM184 PF15665.5 PVD34424.1 - 1.4 8.6 61.4 0.029 14.2 6.8 3.7 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DUF4551 PF15087.6 PVD34426.1 - 6.1 5.5 10.4 6.9 5.4 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PBD PF00786.28 PVD34427.1 - 0.041 14.2 0.6 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 P21-Rho-binding domain CAP_GLY PF01302.25 PVD34428.1 - 2.8e-06 27.2 0.1 6.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain EAP30 PF04157.16 PVD34429.1 - 2.9e-33 115.1 1.1 3.5e-33 114.9 1.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family DUF3829 PF12889.7 PVD34429.1 - 0.021 14.3 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Transgly PF00912.22 PVD34429.1 - 0.058 12.8 0.4 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Transglycosylase AIF_C PF14721.6 PVD34430.1 - 9.6e-54 181.3 0.0 1.5e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 PVD34430.1 - 9.2e-39 133.4 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD34430.1 - 2.4e-11 44.0 0.0 5.9e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PVD34430.1 - 1.4e-07 31.6 1.1 0.11 12.5 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PVD34430.1 - 0.00011 21.6 0.1 0.0034 16.7 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD34430.1 - 0.00035 20.3 3.1 0.054 13.1 0.1 3.9 5 0 0 5 5 5 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PVD34430.1 - 0.0011 18.4 0.2 0.049 12.9 0.0 2.1 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 PVD34430.1 - 0.016 13.9 0.2 3.4 6.3 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein DUF1344 PF07076.11 PVD34430.1 - 0.051 13.5 0.2 0.99 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) K_oxygenase PF13434.6 PVD34430.1 - 0.12 11.5 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 PVD34430.1 - 0.17 10.9 0.2 6 5.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Peroxidase_ext PF11895.8 PVD34431.1 - 0.097 12.6 3.3 0.16 11.9 0.1 2.6 2 1 0 2 2 2 0 Fungal peroxidase extension region LSDAT_euk PF18139.1 PVD34432.1 - 4.3e-74 249.3 0.0 2.5e-37 128.7 0.0 2.4 2 0 0 2 2 2 2 SLOG in TRPM LSDAT_prok PF18171.1 PVD34432.1 - 7.7e-20 71.0 0.0 6.2e-05 22.3 0.0 5.5 3 2 0 3 3 3 3 SLOG in TRPM, prokaryote TFR_dimer PF04253.15 PVD34432.1 - 0.035 14.2 5.7 2.6 8.2 0.4 3.3 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain TetR_C_10 PF16295.5 PVD34432.1 - 0.043 14.1 0.7 1.6 9.0 0.1 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YabA PF06156.13 PVD34432.1 - 3.5 8.3 6.8 1.4e+02 3.2 0.0 3.9 3 0 0 3 3 3 0 Initiation control protein YabA LETM1 PF07766.13 PVD34432.1 - 9.8 5.4 17.7 0.9 8.8 1.0 3.1 3 0 0 3 3 3 0 LETM1-like protein KASH_CCD PF14662.6 PVD34433.1 - 8.6e-05 22.5 11.0 8.6e-05 22.5 11.0 10.2 3 2 6 10 10 10 2 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 PVD34433.1 - 0.0014 16.9 30.2 0.0014 16.9 30.2 6.9 2 1 3 6 6 6 2 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 PVD34433.1 - 0.0032 17.7 203.6 0.12 12.6 8.9 11.1 3 2 8 11 11 11 7 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 PVD34433.1 - 0.0047 17.3 0.8 0.0047 17.3 0.8 11.8 12 2 1 13 13 13 5 Flagella accessory protein C (FlaC) Takusan PF04822.13 PVD34433.1 - 0.0058 16.5 2.2 0.0058 16.5 2.2 9.7 8 3 5 13 13 13 2 Takusan Carb_kinase PF01256.17 PVD34434.1 - 1.3e-43 149.3 0.0 5.9e-43 147.1 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Carb_kinase PF01256.17 PVD34435.1 - 3e-56 190.6 0.0 4.2e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 PVD34435.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 PVD34435.1 - 0.044 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF4618 PF15397.6 PVD34436.1 - 0.0056 16.1 15.6 0.0056 16.1 15.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Uds1 PF15456.6 PVD34436.1 - 0.0085 16.3 8.9 0.0085 16.3 8.9 2.8 2 1 1 3 3 3 1 Up-regulated During Septation DUF4164 PF13747.6 PVD34436.1 - 0.06 13.6 8.1 0.18 12.1 8.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 PVD34436.1 - 0.15 9.9 13.8 0.24 9.3 13.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 PVD34436.1 - 0.34 9.4 18.8 0.49 8.9 18.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF1664 PF07889.12 PVD34436.1 - 0.61 10.1 9.7 1.5 8.8 9.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tho2 PF11262.8 PVD34436.1 - 0.84 8.8 17.2 0.48 9.6 14.6 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 PVD34436.1 - 5.4 6.5 14.8 9.9 5.6 14.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRR_8 PF13855.6 PVD34438.1 - 7.4e-18 64.1 13.5 1.3e-11 44.1 4.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD34438.1 - 1.8e-09 37.7 20.2 3.3e-06 27.3 1.6 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD34438.1 - 0.021 15.3 17.3 3 8.8 1.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4407 PF14362.6 PVD34438.1 - 0.075 12.4 3.8 0.12 11.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 PVD34438.1 - 0.18 11.0 0.3 0.27 10.4 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Atrophin-1 PF03154.15 PVD34438.1 - 0.28 9.4 18.7 0.36 9.1 18.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3619 PF12279.8 PVD34438.1 - 0.56 10.5 4.0 1.7 9.0 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF2072 PF09845.9 PVD34438.1 - 1 9.6 9.8 4.6 7.5 10.4 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein Borrelia_P83 PF05262.11 PVD34438.1 - 1.8 7.0 22.3 2.4 6.5 22.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 PVD34438.1 - 3 8.3 7.4 5.9 7.3 7.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Bud13 PF09736.9 PVD34438.1 - 3.2 8.2 19.8 5.9 7.3 19.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex V_ATPase_I PF01496.19 PVD34438.1 - 3.4 5.5 9.9 5 4.9 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 PVD34438.1 - 6.3 5.6 19.4 11 4.7 19.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pam16 PF03656.13 PVD34439.1 - 8.6e-41 138.9 4.4 1e-40 138.7 4.4 1.0 1 0 0 1 1 1 1 Pam16 Ribosomal_L22 PF00237.19 PVD34439.1 - 0.042 14.1 0.2 0.081 13.2 0.2 1.6 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e Integrase_Zn PF02022.19 PVD34439.1 - 0.35 10.9 1.4 4.7 7.2 0.4 2.8 3 0 0 3 3 3 0 Integrase Zinc binding domain zf-C2H2 PF00096.26 PVD34440.1 - 2.3e-15 56.1 28.0 0.00021 21.6 2.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD34440.1 - 3.8e-10 39.7 30.9 9.4e-06 25.8 1.4 5.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD34440.1 - 6.1e-09 36.0 23.3 0.0089 16.8 0.8 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 PVD34440.1 - 0.00019 22.0 11.7 0.084 13.5 0.1 4.0 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 PVD34440.1 - 0.00066 19.6 0.9 0.00066 19.6 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PVD34440.1 - 0.044 14.1 10.9 0.82 10.0 1.1 3.2 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 PVD34440.1 - 0.058 13.5 2.5 0.91 9.7 0.0 2.9 3 0 0 3 3 2 0 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 PVD34440.1 - 0.13 12.2 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_C2H2_ZHX PF18387.1 PVD34440.1 - 0.19 11.4 2.0 0.19 11.4 0.5 1.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 PVD34440.1 - 0.24 11.7 18.5 0.099 13.0 1.4 4.1 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD34440.1 - 0.27 11.7 14.9 0.16 12.4 1.5 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 PVD34440.1 - 0.71 10.0 10.0 6.3 6.9 1.5 3.5 1 1 1 3 3 3 0 Aberrant zinc-finger CxC6 PF18721.1 PVD34440.1 - 8 6.8 7.5 1.4 9.3 2.9 2.1 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases HLH PF00010.26 PVD34443.1 - 3e-15 55.9 0.4 3e-15 55.9 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Lzipper-MIP1 PF14389.6 PVD34443.1 - 0.031 14.6 3.8 0.031 14.6 3.8 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FYTT PF07078.11 PVD34443.1 - 0.38 10.0 4.2 0.63 9.3 4.2 1.2 1 0 0 1 1 1 0 Forty-two-three protein SlyX PF04102.12 PVD34443.1 - 7.8 7.2 11.4 7.7 7.2 1.5 3.1 2 0 0 2 2 2 0 SlyX Kinesin PF00225.23 PVD34448.1 - 1.6e-74 250.9 0.2 1.6e-74 250.9 0.2 2.1 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 PVD34448.1 - 6.4e-23 81.3 0.0 6.4e-23 81.3 0.0 3.0 3 1 1 4 4 4 1 Microtubule binding IL15 PF02372.15 PVD34448.1 - 1.2 9.2 8.1 0.95 9.5 3.9 2.7 2 1 0 2 2 2 0 Interleukin 15 UPF0121 PF03661.13 PVD34449.1 - 7.9e-92 307.0 15.9 1.3e-91 306.3 15.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) NHL PF01436.21 PVD34449.1 - 6e-38 127.0 21.4 3.3e-09 36.3 0.1 7.0 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.19 PVD34449.1 - 4.7e-17 62.7 0.0 1.2e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF5128 PF17170.4 PVD34449.1 - 4.5e-13 49.1 3.3 4.1e-06 26.2 0.2 4.1 1 1 3 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 PVD34449.1 - 9.4e-13 48.3 2.1 0.00084 19.0 0.0 4.8 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Erf4 PF10256.9 PVD34449.1 - 2.9e-06 27.4 0.0 1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4934 PF16288.5 PVD34449.1 - 1.1e-05 25.3 1.6 0.022 14.7 0.1 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF4934) Invasin_D3 PF09134.10 PVD34449.1 - 0.0016 18.7 0.1 0.0062 16.8 0.0 2.0 2 0 0 2 2 2 1 Invasin, domain 3 SBBP PF06739.11 PVD34449.1 - 0.0018 18.3 0.8 0.13 12.2 0.1 2.8 2 0 0 2 2 2 1 Beta-propeller repeat PQQ_2 PF13360.6 PVD34449.1 - 0.086 12.4 0.0 1.2 8.7 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain 4HBT PF03061.22 PVD34449.1 - 0.17 12.2 0.1 0.66 10.4 0.1 2.0 2 0 0 2 2 2 0 Thioesterase superfamily Septin PF00735.18 PVD34450.1 - 4.5e-83 278.8 13.0 9.7e-83 277.7 3.5 3.0 1 1 2 3 3 3 1 Septin MMR_HSR1 PF01926.23 PVD34450.1 - 3.1e-06 27.2 0.2 3.1e-06 27.2 0.2 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 PVD34450.1 - 9.5e-05 22.6 1.0 0.00025 21.3 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD34450.1 - 0.00089 19.5 0.4 0.0034 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 PVD34450.1 - 0.00093 18.8 0.6 0.0029 17.2 0.6 2.0 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 PVD34450.1 - 0.00095 19.6 0.1 0.0032 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Atg14 PF10186.9 PVD34450.1 - 0.0035 16.5 16.9 0.0057 15.8 16.9 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 PVD34450.1 - 0.011 15.8 18.3 0.03 14.4 18.3 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_29 PF13555.6 PVD34450.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 PVD34450.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PVD34450.1 - 0.047 13.6 8.2 0.089 12.7 0.1 3.1 3 1 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 PVD34450.1 - 0.16 11.5 12.9 1.8e+02 1.6 12.8 3.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PVD34450.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.6 2 2 0 2 2 1 0 ABC transporter Peptidase_S49 PF01343.18 PVD34450.1 - 0.28 11.1 3.6 0.67 9.9 3.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 UPF0242 PF06785.11 PVD34450.1 - 0.66 10.0 22.2 1.2 9.2 22.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 PVD34450.1 - 1.1 9.3 11.8 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF4407 PF14362.6 PVD34450.1 - 1.1 8.5 7.8 1.7 7.9 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD34450.1 - 2 7.9 9.7 3 7.3 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 PVD34450.1 - 4.3 7.8 29.5 2.3e+03 -1.1 29.5 2.6 1 1 0 1 1 1 0 AAA domain DUF2630 PF10944.8 PVD34450.1 - 4.4 7.8 14.3 0.69 10.4 7.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) Beach PF02138.18 PVD34451.1 - 1e-123 412.1 1.0 1.6e-123 411.5 1.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 PVD34451.1 - 5.9e-106 353.8 2.3 5.9e-106 353.8 2.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 PVD34451.1 - 5.8e-70 234.3 3.1 1.5e-69 233.0 3.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 PVD34451.1 - 1.2e-25 89.5 0.0 1.2e-25 89.5 0.0 2.6 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 PVD34451.1 - 2.9e-12 47.0 0.0 6.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 PVD34451.1 - 1.9e-06 28.5 6.0 0.42 11.6 0.0 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC2 PF08672.11 PVD34451.1 - 0.12 12.9 0.0 0.53 10.8 0.0 2.1 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Ig_3 PF13927.6 PVD34453.1 - 2.1e-35 121.2 1.5 5e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD34453.1 - 8.3e-34 115.5 0.0 2.4e-12 46.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD34453.1 - 1.9e-26 92.2 1.0 4.3e-11 43.0 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD34453.1 - 3.8e-22 78.2 1.0 1e-06 28.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD34453.1 - 1.4e-19 70.3 7.5 5.8e-08 32.9 0.4 5.1 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD34453.1 - 1.3e-06 27.8 0.0 0.14 11.8 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD34453.1 - 9e-05 22.5 0.0 0.98 9.5 0.0 3.4 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD34453.1 - 0.0094 16.0 0.6 3.4 7.8 0.0 3.1 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 PVD34453.1 - 0.023 14.7 0.4 3.1 7.9 0.0 3.5 4 1 0 4 4 4 0 C17orf99 Ig domain GEMIN8 PF15348.6 PVD34454.1 - 6e-47 160.9 12.8 6e-47 160.9 12.8 1.8 2 0 0 2 2 2 1 Gemini of Cajal bodies-associated protein 8 MBDa PF16564.5 PVD34454.1 - 2.3 8.5 7.1 8.6 6.6 0.6 3.0 3 0 0 3 3 3 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Mg_trans_NIPA PF05653.14 PVD34455.1 - 2.7e-135 450.2 21.3 3.2e-135 449.9 21.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 PVD34455.1 - 0.00016 21.8 8.1 0.00016 21.8 8.1 4.2 3 1 1 4 4 4 2 EamA-like transporter family TarH PF02203.15 PVD34455.1 - 0.14 12.1 0.3 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue Peptidase_S28 PF05577.12 PVD34456.1 - 3.2e-95 319.5 0.8 4e-95 319.2 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 PVD34456.1 - 4.4e-07 29.8 0.2 4.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD34456.1 - 0.00024 20.7 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PVD34456.1 - 0.00051 19.4 0.0 0.0008 18.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 PVD34456.1 - 0.0078 14.9 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_6 PF12697.7 PVD34456.1 - 0.023 15.3 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 PVD34456.1 - 0.063 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) UCH PF00443.29 PVD34457.1 - 3.2e-47 161.2 0.0 9.3e-29 100.7 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD34457.1 - 1.2e-30 107.3 6.8 6.4e-21 75.3 0.5 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PVD34457.1 - 0.00017 21.2 13.2 0.0051 16.3 5.9 3.1 2 1 1 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Med25 PF11232.8 PVD34457.1 - 0.016 15.2 0.2 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Ribosomal_L21e PF01157.18 PVD34458.1 - 7.4e-48 160.6 7.6 4.8e-47 158.0 3.8 2.0 2 0 0 2 2 2 2 Ribosomal protein L21e PBP1_TM PF14812.6 PVD34459.1 - 0.0072 16.7 1.5 0.0072 16.7 1.5 1.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Ctf8 PF09696.10 PVD34459.1 - 0.17 12.2 0.5 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 Ctf8 CitMHS PF03600.16 PVD34460.1 - 3.7e-59 200.4 17.2 3.7e-59 200.4 17.2 2.0 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 PVD34460.1 - 7.5e-16 58.2 36.5 7.3e-12 45.1 13.1 2.3 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ATP-synt_C PF00137.21 PVD34460.1 - 0.35 11.2 8.1 1.2 9.6 2.2 3.4 2 0 0 2 2 2 0 ATP synthase subunit C DUF588 PF04535.12 PVD34460.1 - 8.6 6.1 8.8 0.64 9.8 2.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF588) MatC_N PF07158.11 PVD34460.1 - 8.7 6.4 27.5 0.016 15.3 13.4 2.6 2 1 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus WW PF00397.26 PVD34461.1 - 4.4e-07 29.9 6.6 1e-06 28.7 6.6 1.6 1 0 0 1 1 1 1 WW domain MBT PF02820.18 PVD34462.1 - 2.2e-92 303.4 4.2 1.6e-27 95.6 0.1 4.3 4 0 0 4 4 4 4 mbt repeat SAM_1 PF00536.30 PVD34462.1 - 2.1e-10 40.9 0.0 4.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD34462.1 - 3.1e-07 30.4 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AMP-binding PF00501.28 PVD34463.1 - 1.4e-104 350.1 0.0 1.8e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD34463.1 - 1.4e-10 42.0 0.3 3.6e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 PVD34463.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD34464.1 - 3.1e-95 319.3 0.1 4.6e-95 318.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD34464.1 - 1.1e-11 45.5 0.1 3.2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF3_C PF00707.22 PVD34464.1 - 1.4e-06 28.2 1.8 3e-06 27.1 1.8 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 PVD34464.1 - 0.035 13.8 1.9 0.065 12.9 1.4 1.6 1 1 0 1 1 1 0 Mitochondrial translation initiation factor IF3_N PF05198.16 PVD34464.1 - 0.044 14.1 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Pkinase_Tyr PF07714.17 PVD34465.1 - 1.8e-92 309.3 0.3 2.6e-92 308.8 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD34465.1 - 3.6e-48 164.2 0.0 6.5e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD34465.1 - 3.7e-22 78.2 0.1 9.2e-22 76.9 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD34465.1 - 7.3e-16 57.5 1.4 1.4e-15 56.6 0.3 2.0 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 PVD34465.1 - 1.1e-15 58.0 0.6 2.8e-15 56.7 0.3 1.8 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 PVD34465.1 - 1.3e-12 47.3 0.4 5.6e-12 45.3 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PVD34465.1 - 7.9e-09 35.1 0.1 2.9e-08 33.3 0.1 2.1 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 PVD34465.1 - 9.2e-06 25.4 0.2 2.1e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 BTK motif hSH3 PF14603.6 PVD34465.1 - 4.5e-05 23.8 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 Helically-extended SH3 domain Kinase-like PF14531.6 PVD34465.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SH3_10 PF17902.1 PVD34465.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.6 PVD34465.1 - 0.0019 18.6 2.3 0.0094 16.4 2.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_3 PF08239.11 PVD34465.1 - 0.0098 16.2 0.2 0.021 15.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 PVD34465.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PVD34465.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1819 PF08849.11 PVD34465.1 - 0.072 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) PH_8 PF15409.6 PVD34465.1 - 1.1 9.6 7.7 0.14 12.5 2.2 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain PGM_PMM_I PF02878.16 PVD34466.1 - 7.6e-33 113.1 0.0 1.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PVD34466.1 - 2.9e-23 82.5 0.0 6.8e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PVD34466.1 - 1.5e-13 50.9 0.2 3e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 PVD34466.1 - 3.1e-06 27.3 0.0 8.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain START PF01852.19 PVD34467.1 - 1.7e-31 109.2 0.1 2.2e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 PVD34467.1 - 0.023 14.7 0.1 0.25 11.3 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) Voltage_CLC PF00654.20 PVD34468.1 - 1.3e-101 340.4 21.1 4.1e-100 335.5 19.6 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 PVD34468.1 - 7.6e-07 29.5 0.1 0.00028 21.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 PVD34470.1 - 5.2e-73 246.3 23.4 2.4e-36 125.7 9.4 3.1 2 1 1 3 3 3 3 Voltage gated chloride channel FH2 PF02181.23 PVD34470.1 - 1.9e-34 119.4 3.6 9.9e-32 110.5 3.6 2.2 1 1 0 1 1 1 1 Formin Homology 2 Domain CBS PF00571.28 PVD34470.1 - 4.7e-15 55.8 1.2 1.5e-07 31.7 0.1 2.7 2 0 0 2 2 2 2 CBS domain FH2 PF02181.23 PVD34472.1 - 7.4e-71 239.2 15.9 7.4e-71 239.2 15.9 2.6 1 1 1 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 PVD34472.1 - 3.1e-13 49.7 1.0 3.1e-13 49.7 1.0 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PVD34472.1 - 2.6e-10 40.2 4.8 5.5e-10 39.2 0.0 3.1 2 1 0 2 2 2 1 Diaphanous FH3 Domain Antigen_Bd37 PF11641.8 PVD34472.1 - 0.015 14.8 1.1 0.044 13.3 1.1 1.8 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Duffy_binding PF05424.11 PVD34472.1 - 0.31 11.1 4.5 1.2 9.2 4.4 2.0 1 1 1 2 2 2 0 Duffy binding domain DUF4407 PF14362.6 PVD34472.1 - 1.9 7.8 5.7 3.7 6.8 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 PVD34472.1 - 2.3 8.6 7.1 2.2 8.7 0.6 2.7 2 0 0 2 2 2 0 Tup N-terminal DUF2203 PF09969.9 PVD34472.1 - 4.8 7.9 12.3 0.8 10.4 0.8 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 PVD34472.1 - 9.1 4.8 11.1 7.8 5.0 1.7 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A FH2 PF02181.23 PVD34473.1 - 1.9e-69 234.5 10.8 3.1e-69 233.9 10.8 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD34473.1 - 1.9e-30 106.0 3.2 1.9e-30 106.0 3.2 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PVD34473.1 - 9.6e-11 41.6 0.1 9.6e-11 41.6 0.1 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain WH2 PF02205.20 PVD34473.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 WH2 motif YlqD PF11068.8 PVD34473.1 - 0.022 15.2 1.7 0.022 15.2 1.7 2.7 3 0 0 3 3 3 0 YlqD protein DUF4709 PF15821.5 PVD34473.1 - 0.62 10.4 6.3 1.3 9.3 0.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) HEPN_AbiU2 PF18734.1 PVD34473.1 - 0.85 9.1 7.6 0.057 12.9 1.3 2.2 1 1 1 2 2 2 0 AbiU2 GYR PF02756.14 PVD34473.1 - 4 7.2 4.1 8.4 6.2 4.1 1.5 1 0 0 1 1 1 0 GYR motif Drf_GBD PF06371.13 PVD34474.1 - 3.5e-11 43.0 0.1 6.8e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain CARD PF00619.21 PVD34475.1 - 4.3e-05 23.5 0.1 0.0058 16.6 0.0 3.0 3 0 0 3 3 3 1 Caspase recruitment domain adh_short PF00106.25 PVD34476.1 - 2.2e-34 118.7 0.0 2.8e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD34476.1 - 2.4e-25 89.5 0.0 1.9e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD34476.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD34476.1 - 3.3e-05 23.5 0.0 9.1e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PVD34476.1 - 0.038 14.2 0.0 0.43 10.8 0.0 2.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HATPase_c PF02518.26 PVD34476.1 - 0.059 13.9 0.0 0.21 12.1 0.0 1.9 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 PVD34477.1 - 3e-40 136.7 5.9 5.7e-13 49.3 0.1 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34477.1 - 1.5e-37 127.5 8.2 4.5e-11 43.0 0.5 5.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34477.1 - 2.2e-34 113.6 9.9 0.00019 21.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 PVD34477.1 - 3.3e-32 109.5 18.8 0.00016 21.9 1.3 8.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD34477.1 - 3.4e-28 97.3 11.2 1.1e-05 25.5 0.0 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD34477.1 - 2.1e-06 28.0 0.0 6.2e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 SOCS box cNMP_binding PF00027.29 PVD34478.1 - 1.6e-19 69.8 0.0 2.7e-11 43.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Strabismus PF06638.11 PVD34479.1 - 0.0096 14.6 0.0 0.018 13.7 0.0 1.4 1 0 0 1 1 1 1 Strabismus protein Na_K-ATPase PF00287.18 PVD34479.1 - 0.17 11.1 2.1 0.32 10.1 0.8 1.9 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain VirB8 PF04335.13 PVD34480.1 - 0.00037 20.4 0.0 0.00047 20.1 0.0 1.1 1 0 0 1 1 1 1 VirB8 protein LEM PF03020.15 PVD34486.1 - 2.2e-12 46.3 0.5 2.4e-11 43.0 0.7 2.3 2 0 0 2 2 2 1 LEM domain Ank_2 PF12796.7 PVD34486.1 - 6.4e-09 36.3 0.6 2.4e-05 24.8 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD34486.1 - 1.8e-07 31.3 0.5 0.021 15.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD34486.1 - 2e-05 25.1 0.1 0.00074 20.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34486.1 - 3.2e-05 24.0 1.1 0.0053 17.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PVD34486.1 - 0.00012 22.4 0.2 0.027 14.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat DUF5423 PF17461.2 PVD34486.1 - 0.063 12.1 9.3 0.0066 15.3 4.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5423) PTEN_C2 PF10409.9 PVD34487.1 - 1.7e-22 79.6 0.1 3.1e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 PVD34487.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.31 PVD34487.1 - 5.1e-06 25.9 11.2 7.4e-06 25.4 11.2 1.2 1 0 0 1 1 1 1 Ion transport protein PTPlike_phytase PF14566.6 PVD34487.1 - 4.9e-05 23.5 0.0 9.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PVD34487.1 - 0.00041 20.0 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PVD34487.1 - 0.031 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Neur_chan_LBD PF02931.23 PVD34488.1 - 3.5e-49 167.2 0.4 5e-49 166.7 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD34488.1 - 4.1e-36 125.2 0.3 6e-36 124.7 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD34489.1 - 1.6e-31 109.4 0.1 2.2e-31 109.0 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD34489.1 - 1.2e-28 100.8 0.0 2.9e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region p450 PF00067.22 PVD34491.1 - 3.1e-38 131.7 2.6 1.3e-23 83.6 0.3 2.1 1 1 1 2 2 2 2 Cytochrome P450 UXS1_N PF11803.8 PVD34491.1 - 3.5 8.1 4.9 1.1e+02 3.2 0.1 3.4 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Tmem26 PF09772.9 PVD34492.1 - 5.4e-45 154.0 5.7 7.5e-45 153.5 5.7 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 p450 PF00067.22 PVD34493.1 - 4.6e-34 118.0 0.3 2.3e-30 105.7 0.0 2.6 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD34494.1 - 1.4e-69 235.0 0.2 6e-36 124.2 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 TMEM251 PF15190.6 PVD34494.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 251 DUF4801 PF16059.5 PVD34495.1 - 3.9e-14 52.3 23.8 5e-14 52.0 10.6 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4801) DCX PF03607.17 PVD34496.1 - 8.1e-36 121.9 0.1 8.5e-20 70.6 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Pkinase PF00069.25 PVD34497.1 - 1.1e-33 116.7 0.0 2.3e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34497.1 - 4.2e-07 29.5 0.0 2.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SAICAR_synt PF01259.18 PVD34498.1 - 4.4e-53 180.5 0.0 5.6e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 PVD34498.1 - 1.2e-35 122.3 0.0 3.2e-35 120.9 0.0 1.7 1 1 0 1 1 1 1 AIR carboxylase baeRF_family2 PF18844.1 PVD34498.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 SAICAR_synt PF01259.18 PVD34499.1 - 2.1e-53 181.5 0.1 5.2e-53 180.2 0.1 1.6 1 1 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 PVD34499.1 - 3.5e-20 72.1 0.2 6.4e-14 51.8 0.0 2.3 1 1 1 2 2 2 2 AIR carboxylase Transglut_core PF01841.19 PVD34499.1 - 0.012 16.1 0.2 0.098 13.1 0.1 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily baeRF_family2 PF18844.1 PVD34499.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 OAM_dimer PF16554.5 PVD34499.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase GATase_6 PF13522.6 PVD34500.1 - 1.5e-12 47.9 0.0 3.6e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 PVD34500.1 - 1.6e-11 44.0 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 PVD34500.1 - 9.1e-10 38.5 0.0 2e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PVD34500.1 - 1.8e-05 23.8 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 PVD34500.1 - 0.0096 15.4 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.6 PVD34500.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF1248 PF06852.12 PVD34500.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Peptidase_M24 PF00557.24 PVD34501.1 - 3.9e-50 170.4 0.1 6.2e-50 169.8 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PVD34501.1 - 3.3e-31 107.6 0.0 5.4e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Cu2_monoox_C PF03712.15 PVD34501.1 - 0.059 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain HipN PF18253.1 PVD34502.1 - 1.2e-17 63.3 0.0 3.7e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain ABC1 PF03109.16 PVD34502.1 - 2.5e-16 59.9 0.1 1.9e-15 57.1 0.0 2.4 2 0 0 2 2 2 1 ABC1 family STI1 PF17830.1 PVD34502.1 - 4.3e-12 45.8 2.0 8.3e-12 44.9 1.2 2.0 2 0 0 2 2 1 1 STI1 domain TPR_1 PF00515.28 PVD34502.1 - 1.5e-06 27.7 0.5 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD34502.1 - 0.00047 20.1 4.1 0.67 10.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD34502.1 - 0.00093 18.8 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 PVD34502.1 - 0.0099 16.2 0.0 0.038 14.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat APH PF01636.23 PVD34502.1 - 0.046 13.6 0.2 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_8 PF13181.6 PVD34502.1 - 0.06 13.6 2.2 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 PVD34502.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S8e DNA_pol3_gamma3 PF12169.8 PVD34502.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III TPR_16 PF13432.6 PVD34502.1 - 0.16 12.7 0.0 0.36 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 PVD34503.1 - 1.7e-21 76.6 0.2 5e-17 62.3 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD34503.1 - 8.6e-20 68.7 5.5 1.1e-05 25.3 0.0 6.0 6 1 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PVD34503.1 - 3.2e-19 68.4 6.5 0.00018 21.8 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PVD34503.1 - 1.5e-18 66.9 1.0 3.4e-09 37.0 0.4 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34503.1 - 1.1e-16 60.6 0.1 2.3e-11 43.7 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD34503.1 - 5.5e-07 29.8 0.5 1.6e-06 28.3 0.5 1.8 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 PVD34506.1 - 1.5e-30 105.6 6.3 3.3e-10 40.4 0.0 4.9 1 1 5 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD34506.1 - 2.9e-24 84.4 5.2 6.7e-06 26.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 PVD34506.1 - 1.1e-23 80.7 4.1 0.0017 18.7 0.0 7.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 PVD34506.1 - 1.9e-22 79.3 4.4 1.7e-09 38.0 0.1 6.6 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34506.1 - 3.8e-20 71.7 11.5 6.9e-06 26.2 0.2 6.8 4 1 4 8 8 8 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD34506.1 - 8.6e-07 29.2 1.5 1.9e-06 28.1 1.5 1.6 1 0 0 1 1 1 1 SOCS box UDPG_MGDP_dh_C PF03720.15 PVD34506.1 - 0.088 13.2 0.2 35 4.9 0.0 3.3 3 2 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain zf-CCHC_3 PF13917.6 PVD34507.1 - 4.8e-17 61.6 3.7 8.8e-17 60.8 3.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Macoilin PF09726.9 PVD34507.1 - 4e-05 22.4 15.6 4.1e-05 22.4 15.6 1.1 1 0 0 1 1 1 1 Macoilin family SDA1 PF05285.12 PVD34507.1 - 0.00065 19.2 18.2 0.00085 18.9 18.2 1.1 1 0 0 1 1 1 1 SDA1 Apt1 PF10351.9 PVD34507.1 - 0.00076 18.5 20.5 0.00088 18.2 20.5 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Nop14 PF04147.12 PVD34507.1 - 0.0021 16.3 15.5 0.0025 16.1 15.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF5486 PF17588.2 PVD34507.1 - 0.032 14.1 0.2 0.086 12.7 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Presenilin PF01080.17 PVD34507.1 - 0.11 11.2 14.0 0.14 10.9 14.0 1.1 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 PVD34507.1 - 0.35 8.6 19.8 0.41 8.4 19.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 PVD34507.1 - 0.81 7.9 21.6 1.2 7.3 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 PVD34507.1 - 1.1 7.5 28.5 1.4 7.1 28.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIF_alpha PF05793.12 PVD34507.1 - 2.1 6.9 25.8 2.7 6.5 25.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 PVD34507.1 - 2.8 7.4 20.0 3.7 7.0 20.0 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 PVD34507.1 - 3.4 6.3 13.1 4.4 6.0 13.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 PVD34507.1 - 5.5 4.0 14.3 6.4 3.7 14.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 PVD34507.1 - 5.5 7.0 7.9 8.7 6.3 7.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 PVD34507.1 - 6.4 7.0 20.4 9.9 6.4 20.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hid1 PF12722.7 PVD34507.1 - 9 4.3 22.6 12 3.9 22.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cadherin PF00028.17 PVD34509.1 - 9.6e-33 112.5 0.1 1.8e-12 47.5 0.0 3.3 3 0 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 PVD34509.1 - 1e-13 50.9 0.5 5.6e-11 42.1 0.0 3.4 3 0 0 3 3 3 1 Cadherin-like Cadherin_3 PF16184.5 PVD34509.1 - 0.0039 17.2 1.0 0.26 11.3 0.0 2.9 3 1 0 3 3 3 1 Cadherin-like Cadherin PF00028.17 PVD34510.1 - 3.3e-48 162.1 0.0 7.3e-19 68.0 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain RET_CLD1 PF17756.1 PVD34510.1 - 0.011 16.0 0.0 3.9 7.8 0.0 2.6 2 0 0 2 2 2 0 RET Cadherin like domain 1 Protocadherin PF08374.11 PVD34510.1 - 0.019 14.9 0.4 0.032 14.2 0.4 1.3 1 0 0 1 1 1 0 Protocadherin TQ PF18202.1 PVD34510.1 - 0.04 14.4 0.2 4.1 7.9 0.1 2.5 2 0 0 2 2 2 0 T-Q ester bond containing domain Cadherin_2 PF08266.12 PVD34510.1 - 0.07 13.0 0.3 4.3 7.2 0.0 3.4 4 0 0 4 4 4 0 Cadherin-like EphA2_TM PF14575.6 PVD34510.1 - 0.13 13.1 0.3 0.26 12.2 0.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BTB PF00651.31 PVD34512.1 - 1.4e-11 44.6 0.0 2.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD34512.1 - 0.004 17.2 1.0 0.024 14.7 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch MFS_1 PF07690.16 PVD34513.1 - 0.0012 17.9 7.5 0.0012 17.9 7.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Cadherin PF00028.17 PVD34516.1 - 5e-42 142.2 1.5 2e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 Cadherin domain Cadherin_3 PF16184.5 PVD34516.1 - 8.7e-06 25.7 1.0 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 Cadherin-like Protocadherin PF08374.11 PVD34516.1 - 0.027 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Protocadherin Invasin_D3 PF09134.10 PVD34516.1 - 0.065 13.5 2.0 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 Invasin, domain 3 Herpes_gE PF02480.16 PVD34516.1 - 0.071 11.8 0.2 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 PVD34516.1 - 0.085 11.7 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Amnionless RET_CLD1 PF17756.1 PVD34516.1 - 0.18 12.1 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin_4 PF17803.1 PVD34516.1 - 0.63 10.7 5.3 4.6 7.9 0.3 3.0 2 1 0 2 2 2 0 Bacterial cadherin-like domain Syndecan PF01034.20 PVD34516.1 - 0.76 9.7 3.5 1.7 8.6 3.5 1.5 1 0 0 1 1 1 0 Syndecan domain Cadherin PF00028.17 PVD34517.1 - 5.6e-50 167.7 2.1 2.6e-17 63.0 0.0 4.2 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 PVD34517.1 - 7.7e-12 44.9 0.2 1.1e-08 34.7 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 PVD34517.1 - 1.5e-06 28.7 9.1 0.014 16.0 0.1 3.7 3 0 0 3 3 3 2 Bacterial cadherin-like domain Cadherin_3 PF16184.5 PVD34517.1 - 7e-05 22.8 4.5 0.45 10.5 0.0 4.0 4 0 0 4 4 4 2 Cadherin-like Med13_C PF06333.12 PVD34518.1 - 0.043 13.1 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Cadherin PF00028.17 PVD34522.1 - 2.4e-87 287.5 6.6 6.2e-18 65.0 0.0 6.4 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 PVD34522.1 - 7.7e-08 32.1 3.5 0.086 12.7 0.2 5.1 5 0 0 5 5 5 3 Cadherin-like Cadherin_pro PF08758.11 PVD34522.1 - 0.0045 17.1 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 Cadherin prodomain like 7tm_1 PF00001.21 PVD34523.1 - 1.1e-55 188.8 11.1 1.1e-55 188.8 11.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD34523.1 - 2.6e-08 33.6 21.0 1.3e-06 28.0 12.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD34523.1 - 9.5e-06 25.4 15.9 9.5e-06 25.4 15.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD34523.1 - 0.0016 18.2 18.1 0.0018 18.1 15.7 2.1 2 1 0 2 2 2 1 Olfactory receptor Git3 PF11710.8 PVD34523.1 - 0.022 14.5 13.3 0.019 14.8 9.2 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Wzz PF02706.15 PVD34523.1 - 0.21 11.9 0.8 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Chain length determinant protein cNMP_binding PF00027.29 PVD34526.1 - 1.3e-08 34.8 0.0 4.2e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain C1q PF00386.21 PVD34527.1 - 4.9e-22 78.5 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 C1q domain Spc29 PF17082.5 PVD34527.1 - 0.0026 17.6 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 DivIC PF04977.15 PVD34527.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator NolB PF17398.2 PVD34527.1 - 0.096 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolB TMEM192 PF14802.6 PVD34527.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 TMEM192 family C1q PF00386.21 PVD34528.1 - 4.2e-39 133.7 0.0 2.6e-20 72.9 0.0 2.2 1 1 1 2 2 2 2 C1q domain PA14 PF07691.12 PVD34528.1 - 0.0025 17.6 0.3 0.52 10.1 0.0 3.4 3 1 0 3 3 3 1 PA14 domain GLEYA PF10528.9 PVD34528.1 - 0.0026 18.2 0.6 0.17 12.4 0.1 3.4 2 2 0 2 2 2 1 GLEYA domain Pirin_C_2 PF17954.1 PVD34528.1 - 0.12 12.5 0.2 7.6 6.8 0.0 2.9 2 1 1 3 3 3 0 Quercetinase C-terminal cupin domain PQQ PF01011.21 PVD34528.1 - 2.3 8.3 4.3 69 3.6 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat PLAT PF01477.23 PVD34529.1 - 2.3e-09 37.8 0.2 3.2e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain Phage_Orf51 PF06194.11 PVD34529.1 - 0.096 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 Lipoxygenase PF00305.19 PVD34530.1 - 7.7e-59 199.8 0.0 7.8e-41 140.3 0.0 2.9 1 1 2 3 3 3 3 Lipoxygenase DNA_pol3_delta2 PF13177.6 PVD34531.1 - 1.4e-08 34.7 1.8 1.4e-08 34.7 0.6 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 PVD34531.1 - 9.4e-06 25.5 0.0 2.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 PVD34531.1 - 0.00014 22.3 0.1 0.00028 21.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPgrasp_ST PF14397.6 PVD34531.1 - 0.0015 17.8 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Resolvase PF00239.21 PVD34531.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain Sigma54_activ_2 PF14532.6 PVD34531.1 - 0.044 13.9 0.2 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Rep_fac_C PF08542.11 PVD34531.1 - 0.046 14.1 0.1 0.48 10.9 0.0 2.5 3 0 0 3 3 3 0 Replication factor C C-terminal domain FH2 PF02181.23 PVD34532.1 - 1.8e-34 119.5 13.2 3.8e-24 85.5 2.2 3.7 3 1 1 4 4 4 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD34532.1 - 6.3e-23 81.4 6.1 6.3e-23 81.4 6.1 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PVD34532.1 - 1.6e-13 50.7 2.5 1.8e-13 50.4 0.1 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Gp-FAR-1 PF05823.12 PVD34532.1 - 0.029 14.7 3.2 2.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Transcrip_act PF04949.13 PVD34532.1 - 0.031 14.2 0.3 0.031 14.2 0.3 2.1 2 0 0 2 2 2 0 Transcriptional activator VPS28 PF03997.12 PVD34532.1 - 0.086 12.5 3.3 0.12 12.0 0.2 2.5 2 0 0 2 2 2 0 VPS28 protein AbiH PF14253.6 PVD34532.1 - 0.99 9.2 4.1 0.43 10.4 0.5 2.0 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Baculo_PEP_C PF04513.12 PVD34532.1 - 1.5 8.9 8.9 0.97 9.5 0.9 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Neurochondrin PF05536.11 PVD34533.1 - 1.2e-99 334.3 10.9 1.7e-78 264.5 6.7 2.2 2 0 0 2 2 2 2 Neurochondrin IBN_N PF03810.19 PVD34533.1 - 0.014 15.3 1.9 0.28 11.1 0.1 3.2 2 1 1 3 3 3 0 Importin-beta N-terminal domain Pkinase_Tyr PF07714.17 PVD34534.1 - 2.2e-91 305.7 0.0 3.4e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD34534.1 - 9.7e-42 143.1 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PVD34534.1 - 1.8e-17 63.1 7.0 1.1e-05 25.4 0.1 4.7 4 1 0 4 4 4 4 IPT/TIG domain Kinase-like PF14531.6 PVD34534.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TMEM154 PF15102.6 PVD34534.1 - 0.15 12.0 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family CUB_2 PF02408.20 PVD34535.1 - 1.2e-07 31.5 0.0 5.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 CUB-like domain CUB PF00431.20 PVD34535.1 - 2.2e-05 24.8 0.0 0.055 13.8 0.0 2.5 2 1 0 2 2 2 2 CUB domain Propeptide_C25 PF08126.11 PVD34535.1 - 0.2 10.7 0.0 0.62 9.1 0.0 1.7 2 0 0 2 2 2 0 Propeptide_C25 Neur_chan_LBD PF02931.23 PVD34536.1 - 3.2e-54 183.6 5.5 2.9e-36 124.9 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD34536.1 - 6.8e-08 32.9 0.3 0.0022 18.1 0.5 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tweety PF04906.13 PVD34536.1 - 0.023 13.4 0.3 0.036 12.7 0.3 1.2 1 0 0 1 1 1 0 Tweety Ac76 PF05814.11 PVD34536.1 - 0.093 12.8 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) Alk_phosphatase PF00245.20 PVD34537.1 - 1e-140 469.4 0.5 1.3e-140 469.1 0.5 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 PVD34537.1 - 4.8e-06 26.1 0.0 5.8e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 PVD34538.1 - 9e-135 449.8 1.2 1.1e-134 449.6 1.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 PVD34538.1 - 1.3e-05 24.8 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 PVD34539.1 - 1.6e-114 383.1 0.0 5.9e-90 302.2 0.1 2.0 1 1 1 2 2 2 2 Alkaline phosphatase Lectin_C PF00059.21 PVD34541.1 - 2.8e-06 28.0 0.1 6.5e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 PVD34541.1 - 0.073 13.3 0.4 0.073 13.3 0.4 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD34542.1 - 1e-15 57.2 1.5 1.9e-07 30.7 0.4 2.2 1 1 1 2 2 2 2 Leucine rich repeat Ldl_recept_a PF00057.18 PVD34542.1 - 2.1e-10 40.7 19.5 0.00012 22.2 7.7 3.2 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A LRR_4 PF12799.7 PVD34542.1 - 6.5e-10 39.1 2.3 1.6e-05 25.2 0.1 2.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD34542.1 - 4.5e-06 26.7 0.1 7.1e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD34542.1 - 0.0025 18.1 3.6 1.2 10.0 0.1 4.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD34542.1 - 0.0083 15.6 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PVD34542.1 - 0.011 15.7 0.3 28 5.1 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Metallothio_6 PF05522.11 PVD34542.1 - 1.1 9.8 8.3 2.2 8.8 8.3 1.5 1 0 0 1 1 1 0 Metallothionein ASD2 PF08687.11 PVD34543.1 - 2e-62 211.4 23.6 2e-62 211.4 23.6 2.2 2 1 0 2 2 2 1 Apx/Shroom domain ASD2 PDZ PF00595.24 PVD34544.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD34544.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD34544.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 PVD34545.1 - 2e-20 72.7 19.4 0.0086 16.9 0.1 9.9 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD34545.1 - 0.00011 22.4 0.2 10 6.5 0.0 4.5 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD34545.1 - 0.056 12.1 0.8 0.75 8.4 0.2 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD34545.1 - 0.1 11.3 0.0 10 4.7 0.0 3.3 3 1 1 4 4 4 0 Nup133 N terminal like Sedlin_N PF04628.13 PVD34546.1 - 2.6e-36 124.6 0.2 3.8e-36 124.1 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF5424 PF17462.2 PVD34546.1 - 0.032 14.2 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5424) UPF0203 PF05254.12 PVD34546.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cadherin_3 PF16184.5 PVD34547.1 - 2.4e-117 384.9 12.7 5.6e-25 87.5 0.0 9.2 10 0 0 10 10 10 7 Cadherin-like Big_9 PF17963.1 PVD34547.1 - 8.4e-10 39.3 18.0 0.00018 22.2 2.1 6.5 6 2 0 6 6 6 3 Bacterial Ig domain Cadherin_4 PF17803.1 PVD34547.1 - 0.077 13.6 0.4 0.077 13.6 0.4 5.6 6 0 0 6 6 6 0 Bacterial cadherin-like domain Cadherin_3 PF16184.5 PVD34548.1 - 7.2e-25 87.1 0.4 1.4e-13 50.9 0.1 3.1 3 0 0 3 3 3 3 Cadherin-like PBSX_XtrA PF17356.2 PVD34548.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Cadherin_3 PF16184.5 PVD34549.1 - 4.5e-40 136.1 4.5 9.6e-30 102.8 0.6 2.9 3 0 0 3 3 3 2 Cadherin-like Big_9 PF17963.1 PVD34549.1 - 1.7e-08 35.1 0.5 2.1e-05 25.2 0.1 2.5 2 0 0 2 2 2 2 Bacterial Ig domain Calx-beta PF03160.14 PVD34550.1 - 2.1e-37 127.3 6.9 4.7e-15 55.6 1.6 3.3 3 1 0 3 3 3 3 Calx-beta domain Calx-beta PF03160.14 PVD34551.1 - 4.6e-30 103.8 11.6 6.3e-15 55.2 2.7 2.7 2 0 0 2 2 2 2 Calx-beta domain RCR PF12273.8 PVD34551.1 - 0.0017 19.0 0.1 0.0045 17.6 0.1 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 PVD34551.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Ribosomal_L28 PF00830.19 PVD34552.1 - 3e-05 24.1 0.0 7.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal L28 family TPR_1 PF00515.28 PVD34553.1 - 2e-90 293.3 41.2 1.5e-07 30.9 0.1 23.4 24 1 0 24 24 24 18 Tetratricopeptide repeat TPR_2 PF07719.17 PVD34553.1 - 8.3e-68 219.2 41.3 8.5e-06 25.5 0.6 22.8 22 2 0 22 22 22 14 Tetratricopeptide repeat TPR_11 PF13414.6 PVD34553.1 - 1.6e-63 210.2 44.4 0.00011 21.8 0.0 19.9 14 4 6 20 20 20 16 TPR repeat TPR_8 PF13181.6 PVD34553.1 - 3.6e-45 148.4 30.5 0.00022 21.2 0.1 20.3 20 1 1 21 21 20 10 Tetratricopeptide repeat TPR_9 PF13371.6 PVD34553.1 - 3.3e-44 148.9 31.9 6.4e-06 26.2 0.2 13.7 7 5 8 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.6 PVD34553.1 - 9.6e-40 135.0 31.2 4.6e-06 27.2 0.1 14.2 9 2 5 15 15 15 8 Tetratricopeptide repeat TPR_17 PF13431.6 PVD34553.1 - 3.8e-38 127.1 31.9 0.02 15.2 0.2 17.1 16 1 1 17 17 16 10 Tetratricopeptide repeat TPR_12 PF13424.6 PVD34553.1 - 2e-24 85.7 27.1 0.00013 22.2 0.2 13.1 8 3 7 15 15 15 6 Tetratricopeptide repeat TPR_14 PF13428.6 PVD34553.1 - 2.7e-22 77.5 25.2 0.14 13.1 0.0 14.5 9 4 6 15 15 15 5 Tetratricopeptide repeat TPR_7 PF13176.6 PVD34553.1 - 4.4e-19 67.0 12.5 0.051 13.6 0.1 14.6 16 0 0 16 16 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD34553.1 - 2.6e-16 59.9 27.4 0.01 16.3 0.1 11.1 11 1 2 13 13 11 5 Tetratricopeptide repeat TPR_6 PF13174.6 PVD34553.1 - 1.1e-11 44.6 38.2 0.39 11.5 0.0 17.7 21 0 0 21 21 19 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD34553.1 - 1.7e-07 30.9 19.7 3.5 7.6 0.0 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PVD34553.1 - 2e-06 27.1 0.0 4.6 6.8 0.0 7.7 11 0 0 11 11 9 1 SHNi-TPR DUF3856 PF12968.7 PVD34553.1 - 9e-05 22.6 0.5 0.29 11.2 0.0 5.0 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 PVD34553.1 - 0.00078 19.6 33.1 3.2 8.1 0.1 8.9 7 2 2 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 PVD34553.1 - 0.00085 18.3 20.9 0.0097 14.9 0.2 6.0 5 3 2 7 7 6 2 NMDA receptor-regulated protein 1 BTAD PF03704.17 PVD34553.1 - 0.12 12.9 4.6 13 6.2 0.1 4.7 5 0 0 5 5 4 0 Bacterial transcriptional activator domain DUF627 PF04781.12 PVD34553.1 - 0.21 11.6 1.2 2.8 8.0 0.1 3.3 3 1 0 3 3 2 0 Protein of unknown function (DUF627) TPR_MalT PF17874.1 PVD34553.1 - 1 8.6 7.8 1.2 8.4 0.2 4.0 4 1 0 4 4 4 0 MalT-like TPR region ANAPC5 PF12862.7 PVD34553.1 - 2.1 8.5 7.9 6.6 6.9 1.0 5.0 5 1 0 5 5 4 0 Anaphase-promoting complex subunit 5 TPR_21 PF09976.9 PVD34553.1 - 5.7 6.6 9.9 19 4.9 0.1 4.3 4 1 0 5 5 5 0 Tetratricopeptide repeat-like domain 7TM_GPCR_Srw PF10324.9 PVD34554.1 - 9.5e-10 38.3 8.3 1.2e-09 37.9 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD34554.1 - 6.2e-07 29.0 14.6 7.6e-07 28.7 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AA_permease_C PF13906.6 PVD34554.1 - 1.3 9.2 8.9 4.9 7.3 0.3 3.3 3 0 0 3 3 3 0 C-terminus of AA_permease DUF3138 PF11336.8 PVD34556.1 - 1.4 7.5 0.0 1.4 7.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) 4HBT PF03061.22 PVD34557.1 - 0.039 14.3 0.6 0.045 14.1 0.6 1.3 1 1 0 1 1 1 0 Thioesterase superfamily TPR_8 PF13181.6 PVD34558.1 - 1.2e-09 37.6 17.2 1.7e-05 24.7 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD34558.1 - 1.3e-08 35.0 14.5 7.6e-08 32.5 2.7 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD34558.1 - 4.5e-08 32.6 19.6 0.0015 18.5 0.5 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD34558.1 - 2e-07 30.6 3.4 0.0013 18.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD34558.1 - 1e-06 28.3 22.5 2.8e-05 23.7 2.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD34558.1 - 2e-05 24.3 7.4 2.6e-05 23.9 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD34558.1 - 0.00011 22.7 1.7 0.29 11.8 0.3 3.6 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD34558.1 - 0.00012 22.5 7.0 1.9 9.3 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC5 PF12862.7 PVD34558.1 - 0.00081 19.4 4.9 0.062 13.4 2.0 4.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 PVD34558.1 - 0.0013 18.4 0.8 0.0013 18.4 0.8 4.1 3 2 3 6 6 6 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 PVD34558.1 - 0.0022 17.4 2.2 0.0022 17.4 2.2 1.9 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 PVD34558.1 - 0.04 14.7 8.9 2.1 9.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 PVD34558.1 - 0.096 12.8 0.1 25 5.1 0.1 3.1 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.6 PVD34558.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD34558.1 - 1.1 9.6 13.4 1.1 9.7 0.2 4.5 4 1 2 6 6 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 PVD34558.1 - 1.6 9.3 6.9 0.7 10.5 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) Bromo_TP PF07524.13 PVD34559.1 - 8.9e-14 51.3 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 PVD34559.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 Histone-fold protein DUF935 PF06074.12 PVD34559.1 - 0.15 10.7 1.3 0.21 10.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF935) AFP_2 PF18815.1 PVD34560.1 - 0.042 14.1 2.0 0.09 13.0 0.1 2.7 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat ASTN_2_hairpin PF18577.1 PVD34560.1 - 0.57 10.3 4.7 4.6 7.4 0.5 4.0 3 0 0 3 3 3 0 Astrotactin-2 C-terminal beta-hairpin domain LRR_4 PF12799.7 PVD34561.1 - 0.042 14.3 1.7 2.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD34561.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeat SNF PF00209.18 PVD34562.1 - 2e-162 541.6 40.1 1.7e-146 489.0 32.2 2.4 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family TMEM154 PF15102.6 PVD34563.1 - 0.011 15.7 2.2 0.011 15.7 2.2 2.2 1 1 1 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 PVD34563.1 - 0.027 13.2 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MHYT PF03707.16 PVD34563.1 - 0.095 12.9 0.7 0.21 11.8 0.7 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF4711 PF15829.5 PVD34563.1 - 0.13 12.2 1.2 0.19 11.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Saf_2TM PF18303.1 PVD34563.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF5305 PF17231.2 PVD34563.1 - 0.34 10.3 2.6 0.26 10.6 0.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5305) ORC6 PF05460.13 PVD34563.1 - 1.5 8.1 10.0 1.6 7.9 10.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SNF2_N PF00176.23 PVD34565.1 - 3e-76 256.4 0.1 5.5e-76 255.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 PVD34565.1 - 1.2e-42 144.5 2.7 3.8e-42 142.9 2.7 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 PVD34565.1 - 5.8e-31 107.5 3.1 8.9e-31 106.9 0.8 2.7 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 PVD34565.1 - 1.3e-20 73.8 0.0 6.3e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HLH PF00010.26 PVD34565.1 - 2.1e-16 59.6 1.8 2.1e-16 59.6 1.8 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ResIII PF04851.15 PVD34565.1 - 5.4e-10 39.5 0.0 1.6e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DBINO PF13892.6 PVD34565.1 - 1.4e-05 25.5 0.1 1.4e-05 25.5 0.1 3.3 3 0 0 3 3 1 1 DNA-binding domain Myb_DNA-binding PF00249.31 PVD34565.1 - 2.5e-05 24.4 0.1 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 PVD34565.1 - 3.4e-05 23.7 0.0 0.00016 21.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 PVD34565.1 - 0.015 14.5 1.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 PVD34565.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase pEK499_p136 PF18736.1 PVD34565.1 - 0.031 13.9 0.5 0.066 12.8 0.5 1.5 1 0 0 1 1 1 0 HEPN pEK499 p136 DUF4800 PF16057.5 PVD34565.1 - 0.25 10.6 3.1 0.18 11.1 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) CDH1_2_SANT_HL1 PF18375.1 PVD34565.1 - 0.68 10.7 3.4 22 5.8 0.1 2.9 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 ZZ PF00569.17 PVD34566.1 - 6.9e-12 45.0 3.2 1.2e-11 44.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 PVD34566.1 - 3.7e-10 39.6 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain UBA_5 PF16577.5 PVD34566.1 - 2.2e-09 37.3 0.1 4.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 UBA domain C1_2 PF03107.16 PVD34566.1 - 0.018 15.4 4.3 0.04 14.2 4.3 1.6 1 0 0 1 1 1 0 C1 domain DctP PF03480.13 PVD34567.1 - 0.12 11.6 0.4 0.19 11.0 0.4 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 PDZ PF00595.24 PVD34568.1 - 2e-14 53.7 0.2 6.8e-14 52.0 0.2 1.9 2 0 0 2 2 2 1 PDZ domain WW PF00397.26 PVD34568.1 - 6.9e-11 42.0 2.2 1.2e-10 41.2 2.2 1.4 1 0 0 1 1 1 1 WW domain PDZ_6 PF17820.1 PVD34568.1 - 1.7e-09 37.4 0.7 1.3e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD34568.1 - 0.0022 18.3 0.0 0.082 13.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain DUF5082 PF16888.5 PVD34568.1 - 0.012 15.9 9.7 0.07 13.4 4.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ERM PF00769.19 PVD34568.1 - 7.1 6.4 20.1 2.4 7.9 13.9 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Rad60-SLD_2 PF13881.6 PVD34569.1 - 5.8e-28 97.2 0.0 7e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PVD34569.1 - 3.3e-06 26.8 0.0 1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PVD34569.1 - 0.034 14.7 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF885 PF05960.11 PVD34570.1 - 2.7e-102 344.2 0.0 3.9e-82 277.6 0.0 3.0 2 1 1 3 3 3 3 Bacterial protein of unknown function (DUF885) FSA_C PF10479.9 PVD34571.1 - 1.5e-166 555.6 8.9 1.6e-133 446.4 0.6 3.6 2 1 1 3 3 3 3 Fragile site-associated protein C-terminus C1q PF00386.21 PVD34572.1 - 4e-13 49.7 0.0 9.5e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 C1q domain SOGA PF11365.8 PVD34572.1 - 0.1 13.7 0.1 8.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein SOGA zf-B_box PF00643.24 PVD34573.1 - 0.00059 19.9 8.1 0.0015 18.6 8.1 1.6 1 0 0 1 1 1 1 B-box zinc finger bZIP_1 PF00170.21 PVD34573.1 - 0.04 14.0 0.3 0.04 14.0 0.3 2.8 3 0 0 3 3 2 0 bZIP transcription factor APC_N_CC PF16689.5 PVD34573.1 - 0.055 13.5 0.9 0.16 12.1 0.9 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain ArfGap PF01412.18 PVD34573.1 - 0.06 13.4 1.5 0.19 11.8 1.5 1.9 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf GAS PF13851.6 PVD34573.1 - 0.18 11.1 13.7 0.084 12.2 8.3 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding zf-HIT PF04438.16 PVD34573.1 - 0.21 11.5 6.9 0.44 10.5 6.9 1.5 1 0 0 1 1 1 0 HIT zinc finger DUF3482 PF11981.8 PVD34573.1 - 0.42 10.0 6.7 1.1 8.5 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) zf-RING_5 PF14634.6 PVD34573.1 - 0.93 9.5 8.1 2.5 8.1 8.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD34573.1 - 0.97 9.4 7.7 2.8 7.9 7.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD34573.1 - 3.5 7.6 6.9 8.8 6.3 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC_tran_CTD PF16326.5 PVD34573.1 - 4.9 7.5 8.4 6.3 7.1 2.0 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain ZapB PF06005.12 PVD34573.1 - 6.6 7.3 10.4 1.1 9.7 0.1 3.7 3 0 0 3 3 3 0 Cell division protein ZapB V-ATPase_G_2 PF16999.5 PVD34573.1 - 7.2 7.1 10.7 0.67 10.4 4.7 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit zf-RING_2 PF13639.6 PVD34573.1 - 8 6.9 8.8 21 5.6 8.8 1.8 1 0 0 1 1 1 0 Ring finger domain Cadherin PF00028.17 PVD34575.1 - 7.7e-13 48.7 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Cadherin domain Cadherin_C_2 PF16492.5 PVD34575.1 - 0.015 16.0 0.1 0.024 15.3 0.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal T4_gp9_10 PF07880.11 PVD34575.1 - 0.048 13.2 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Ninjurin PF04923.12 PVD34575.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 Ninjurin Ly49 PF08391.10 PVD34575.1 - 0.079 13.3 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Orf78 PF06024.12 PVD34575.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 PVD34575.1 - 0.14 13.0 0.3 0.21 12.5 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5527 PF17665.1 PVD34575.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Cadherin PF00028.17 PVD34576.1 - 8.8e-40 135.1 0.3 2.8e-19 69.4 0.1 3.2 3 0 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 PVD34577.1 - 7.1e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Cadherin-like Cadherin PF00028.17 PVD34577.1 - 0.00011 22.5 0.0 0.002 18.5 0.0 2.2 2 0 0 2 2 2 1 Cadherin domain Cadherin_4 PF17803.1 PVD34577.1 - 0.075 13.7 0.9 1.3 9.7 0.6 2.2 2 0 0 2 2 2 0 Bacterial cadherin-like domain DUF3439 PF11921.8 PVD34579.1 - 0.032 14.2 6.5 0.048 13.6 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PDDEXK_7 PF04411.12 PVD34579.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Sporozoite_P67 PF05642.11 PVD34579.1 - 3.2 5.7 6.1 3.3 5.7 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ShK PF01549.24 PVD34580.1 - 0.0015 19.0 4.2 0.0015 19.0 4.2 3.0 3 0 0 3 3 3 1 ShK domain-like Sec7 PF01369.20 PVD34581.1 - 1.2e-31 109.8 0.0 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 PVD34581.1 - 3.4e-06 26.8 0.5 1e-05 25.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD34581.1 - 0.0061 16.4 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF229 PF02995.17 PVD34583.1 - 3.8e-121 405.1 0.0 5e-121 404.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PVD34583.1 - 0.00035 20.1 0.1 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 Sulfatase WD40 PF00400.32 PVD34584.1 - 1.6e-47 158.5 36.4 3.7e-07 30.7 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD34584.1 - 1.5e-13 50.8 5.1 0.098 13.0 0.1 7.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD34584.1 - 2.8e-13 49.4 13.7 0.047 12.3 0.1 7.0 3 2 4 7 7 7 6 Nucleoporin Nup120/160 F-box-like PF12937.7 PVD34584.1 - 1e-11 44.5 3.0 2.1e-11 43.5 3.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD34584.1 - 3.2e-07 30.1 0.9 8.4e-07 28.7 0.9 1.8 1 0 0 1 1 1 1 F-box domain Ge1_WD40 PF16529.5 PVD34584.1 - 0.0016 17.5 9.5 0.76 8.7 0.3 5.1 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 PVD34584.1 - 0.014 14.4 7.2 0.79 8.6 0.1 4.6 2 2 4 6 6 6 0 Partner and localizer of BRCA2 WD40 domain BUD22 PF09073.10 PVD34584.1 - 0.49 9.7 13.9 0.72 9.1 13.9 1.2 1 0 0 1 1 1 0 BUD22 Hira PF07569.11 PVD34584.1 - 9.5 5.9 12.9 12 5.6 0.0 5.4 3 1 4 7 7 7 0 TUP1-like enhancer of split Carb_anhydrase PF00194.21 PVD34586.1 - 7.8e-22 78.0 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 PVD34587.1 - 4.1e-09 36.4 0.0 5.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 PVD34589.1 - 3.4e-24 85.6 4.8 4.9e-24 85.1 4.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4986 PF16375.5 PVD34589.1 - 0.069 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function YWFCY PF14293.6 PVD34589.1 - 2.7 8.4 4.5 20 5.6 0.9 2.5 2 0 0 2 2 2 0 YWFCY protein CD36 PF01130.21 PVD34590.1 - 1.9e-60 204.7 4.9 1.8e-56 191.7 3.7 3.0 1 1 1 2 2 2 2 CD36 family OCIA PF07051.11 PVD34591.1 - 5.7e-31 106.4 0.1 8.9e-31 105.8 0.1 1.2 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) ANAPC_CDC26 PF10471.9 PVD34591.1 - 0.054 14.3 1.5 0.17 12.8 1.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 HSP20 PF00011.21 PVD34592.1 - 2.5e-20 72.5 0.2 3.5e-20 72.1 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PVD34592.1 - 5.9e-06 25.7 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YabP PF07873.11 PVD34592.1 - 0.13 12.0 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 YabP family EGF PF00008.27 PVD34593.1 - 2.3e-34 117.3 144.2 7.1e-08 32.6 11.0 10.8 9 1 1 10 10 10 9 EGF-like domain DSL PF01414.19 PVD34593.1 - 1.3e-18 67.0 3.9 1.3e-18 67.0 3.9 8.3 4 2 5 9 9 9 2 Delta serrate ligand hEGF PF12661.7 PVD34593.1 - 3.8e-17 62.2 114.4 4.4e-05 23.9 6.6 11.8 11 0 0 11 11 11 8 Human growth factor-like EGF EGF_2 PF07974.13 PVD34593.1 - 5.4e-10 39.5 169.9 0.023 15.0 7.1 11.5 11 0 0 11 11 11 10 EGF-like domain EGF_3 PF12947.7 PVD34593.1 - 0.01 16.0 6.2 0.01 16.0 6.2 10.0 8 2 0 9 9 9 0 EGF domain Laminin_EGF PF00053.24 PVD34593.1 - 6.8 6.9 137.4 0.57 10.4 4.1 11.3 1 1 10 11 11 11 0 Laminin EGF domain Kunitz_BPTI PF00014.23 PVD34594.1 - 3.3e-19 68.9 2.8 6.5e-19 67.9 2.8 1.5 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Sushi PF00084.20 PVD34594.1 - 5.6e-14 52.5 3.1 7.8e-06 26.4 0.0 2.7 2 1 0 2 2 2 2 Sushi repeat (SCR repeat) WD40_4 PF16300.5 PVD34595.1 - 1.3e-41 140.2 2.2 5.7e-21 74.1 0.6 2.7 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 PVD34595.1 - 3.6e-18 65.6 5.2 0.002 18.9 0.1 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF1899 PF08953.11 PVD34595.1 - 3.9e-18 65.1 0.7 7.6e-11 41.7 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 PVD34595.1 - 7.3e-12 45.4 1.5 0.00042 20.6 0.2 4.9 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD34595.1 - 0.11 11.1 0.4 5.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 PVD34595.1 - 0.18 10.8 0.6 0.46 9.5 0.1 1.9 3 0 0 3 3 3 0 Coatomer WD associated region DnaJ PF00226.31 PVD34596.1 - 8.3e-27 93.1 4.3 1.5e-26 92.3 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 PVD34596.1 - 1.2e-26 93.6 0.2 1.8e-26 93.0 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 PVD34596.1 - 2.9e-10 40.3 16.4 6.1e-10 39.3 16.4 1.6 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 PVD34596.1 - 0.18 11.5 8.5 0.36 10.5 1.6 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 PVD34596.1 - 9 6.4 19.2 45 4.1 1.0 3.6 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Alpha-amylase PF00128.24 PVD34600.1 - 2.5e-45 155.5 2.8 3.6e-32 112.3 0.1 2.4 3 0 0 3 3 3 2 Alpha amylase, catalytic domain PSI_integrin PF17205.3 PVD34600.1 - 0.011 15.4 0.3 0.023 14.4 0.3 1.5 1 0 0 1 1 1 0 Integrin plexin domain Glyco_hydro_127 PF07944.12 PVD34600.1 - 0.015 13.8 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Alpha-amylase PF00128.24 PVD34601.1 - 1e-86 291.6 0.3 1.4e-86 291.1 0.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PVD34601.1 - 0.00012 22.4 0.2 0.15 12.6 0.0 3.5 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_42C PF08533.10 PVD34601.1 - 0.0058 16.3 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase C-terminal domain Malt_amylase_C PF16657.5 PVD34601.1 - 0.028 14.5 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Imm70 PF15601.6 PVD34601.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 70 HNOBA PF07701.14 PVD34602.1 - 4.1e-60 203.0 0.0 6e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 PVD34602.1 - 1e-51 175.2 0.1 1.5e-51 174.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 PVD34602.1 - 1.5e-46 158.4 0.1 2.5e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 PVD34603.1 - 3e-46 157.6 1.2 4.2e-45 153.9 1.2 2.1 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 PVD34603.1 - 9.8e-44 149.2 0.5 1.2e-36 126.1 0.1 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 PVD34603.1 - 1.6e-21 77.0 0.0 2.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding CAP_N PF01213.19 PVD34605.1 - 0.36 10.3 1.2 0.45 9.9 1.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tubulin PF00091.25 PVD34606.1 - 4e-52 177.3 0.0 4.4e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD34606.1 - 0.019 14.6 0.0 0.066 12.9 0.0 1.7 1 1 1 2 2 2 0 Tubulin domain 2OG-FeII_Oxy_3 PF13640.6 PVD34608.1 - 1.1e-06 29.4 0.0 2.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TIR_2 PF13676.6 PVD34608.1 - 4.1e-06 27.4 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain P4Ha_N PF08336.11 PVD34608.1 - 7.8e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TIR PF01582.20 PVD34608.1 - 0.0005 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain TMEM144 PF07857.12 PVD34609.1 - 3e-69 233.6 12.3 7.2e-64 215.9 7.3 2.9 1 1 1 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 PVD34609.1 - 1.3e-07 31.2 6.7 1.3e-07 31.2 4.3 2.2 2 1 0 2 2 2 1 Sugar transport protein 7TMR-DISM_7TM PF07695.11 PVD34609.1 - 0.15 11.9 14.3 0.062 13.2 8.6 2.8 4 0 0 4 4 4 0 7TM diverse intracellular signalling Ost5 PF05251.12 PVD34609.1 - 2.1 8.7 14.5 3 8.2 0.2 4.7 4 1 2 6 6 6 0 Oligosaccharyltransferase subunit 5 H2TH PF06831.14 PVD34610.1 - 3.4e-11 43.0 0.0 3.2e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-GRF PF06839.12 PVD34610.1 - 2.8e-09 36.9 2.3 2.8e-09 36.9 2.3 3.8 4 0 0 4 4 4 2 GRF zinc finger Fapy_DNA_glyco PF01149.24 PVD34610.1 - 0.00044 20.8 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 PVD34610.1 - 0.006 16.4 4.3 0.016 15.1 4.3 1.8 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS OrfB_Zn_ribbon PF07282.11 PVD34610.1 - 1.1 9.3 7.1 0.18 11.7 2.7 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 PVD34611.1 - 0.00026 21.0 10.3 0.00039 20.4 10.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DUF2735 PF10931.8 PVD34611.1 - 0.6 10.8 0.0 0.6 10.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2735) ABC_membrane PF00664.23 PVD34612.1 - 2.9e-30 105.8 25.6 1.2e-15 57.9 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD34612.1 - 8.6e-22 78.1 0.0 4.3e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 PVD34612.1 - 0.098 12.9 0.0 1.9 8.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain CCDC158 PF15921.5 PVD34614.1 - 5.6e-66 223.2 123.7 2e-63 214.8 117.6 2.2 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 158 CENP-F_leu_zip PF10473.9 PVD34614.1 - 9.5e-08 32.2 18.9 9.5e-08 32.2 18.9 11.2 5 1 4 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Speriolin_C PF15059.6 PVD34616.1 - 3.7e-31 108.2 0.0 6.9e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Speriolin C-terminus GIT1_C PF12205.8 PVD34616.1 - 0.00016 21.7 0.5 0.33 11.1 0.1 2.6 2 1 0 2 2 2 2 G protein-coupled receptor kinase-interacting protein 1 C term Mx_ML PF17536.2 PVD34618.1 - 0.0039 16.9 2.8 99 2.6 0.0 7.9 10 3 1 12 12 12 0 Matrix and Matrix long proteins N-terminal MKT1_N PF12247.8 PVD34618.1 - 0.013 15.8 1.6 52 4.3 0.0 7.2 11 0 0 11 11 11 0 Temperature dependent protein affecting M2 dsRNA replication Ribonuc_red_lgC PF02867.15 PVD34620.1 - 1.2e-190 634.5 0.0 1.5e-190 634.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PVD34620.1 - 5.1e-25 87.3 0.0 1.3e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PVD34620.1 - 1.3e-16 60.9 0.0 3.8e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 PVD34620.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Neur_chan_LBD PF02931.23 PVD34621.1 - 2.8e-38 131.6 0.3 4.1e-38 131.0 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD34621.1 - 6.5e-27 95.1 12.4 2.9e-25 89.7 7.8 2.4 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PVD34622.1 - 1.3e-06 28.1 0.1 2.1e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain TaqI_C PF12950.7 PVD34623.1 - 0.069 13.2 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Neur_chan_LBD PF02931.23 PVD34624.1 - 5.8e-21 74.9 0.4 6.2e-21 74.8 0.4 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain MFS_1_like PF12832.7 PVD34625.1 - 2.1e-54 184.9 0.0 9.9e-28 97.1 0.0 2.0 1 1 1 2 2 2 2 MFS_1 like family Nuc_H_symport PF03825.16 PVD34625.1 - 9.2e-14 51.2 13.0 3.8e-13 49.2 4.2 2.8 3 0 0 3 3 3 2 Nucleoside H+ symporter MFS_1 PF07690.16 PVD34625.1 - 2.1e-07 30.2 28.6 0.0077 15.2 8.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 PVD34625.1 - 1.2e-06 27.6 10.6 0.006 15.4 3.5 2.5 1 1 1 2 2 2 2 LacY proton/sugar symporter BaxI_1 PF12811.7 PVD34625.1 - 0.0038 16.8 4.0 0.0038 16.8 4.0 2.1 3 0 0 3 3 3 1 Bax inhibitor 1 like DUF5391 PF17369.2 PVD34625.1 - 0.013 15.6 5.4 1.1 9.3 2.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5391) SSF PF00474.17 PVD34626.1 - 3.2e-23 82.2 1.2 4.6e-16 58.7 0.0 2.0 1 1 1 2 2 2 2 Sodium:solute symporter family SSF PF00474.17 PVD34627.1 - 9.2e-94 314.6 17.0 9.1e-67 225.7 11.8 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family zf-H2C2_2 PF13465.6 PVD34629.1 - 1.9e-13 50.2 24.0 4.5e-07 30.0 3.7 4.9 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 PVD34629.1 - 3.1e-09 36.8 33.7 0.00014 22.2 4.0 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD34629.1 - 1e-06 29.1 33.1 0.0085 16.8 3.1 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD34629.1 - 0.0049 17.1 14.7 0.021 15.1 1.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD34629.1 - 0.0073 16.3 23.6 0.013 15.5 2.7 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD34629.1 - 0.0084 16.8 11.2 0.68 10.6 1.7 3.2 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 PVD34629.1 - 0.013 15.7 2.7 0.4 11.0 0.2 2.7 2 0 0 2 2 2 0 BolA-like protein zinc_ribbon_15 PF17032.5 PVD34629.1 - 0.14 12.9 7.0 9.7 7.0 3.2 2.7 2 0 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 PVD34629.1 - 2.6 8.2 13.5 5.2 7.3 0.2 3.8 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 PVD34629.1 - 3.3 8.1 17.3 2.2 8.6 1.0 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 PVD34629.1 - 4.1 7.5 8.4 2 8.5 3.3 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid EphA2_TM PF14575.6 PVD34631.1 - 7.7e-05 23.5 0.4 0.00011 23.1 0.4 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 PVD34631.1 - 0.006 16.4 0.1 0.0085 15.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Pilin_N PF07790.11 PVD34631.1 - 0.021 15.7 0.1 0.028 15.4 0.1 1.2 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal FeoB_associated PF12669.7 PVD34631.1 - 0.024 15.0 4.1 0.034 14.5 4.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein YtpI PF14007.6 PVD34631.1 - 0.038 14.1 0.2 0.05 13.7 0.2 1.3 1 0 0 1 1 1 0 YtpI-like protein HisKA_4TM PF16926.5 PVD34631.1 - 0.039 13.5 0.5 0.044 13.4 0.5 1.1 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase GAPT PF11770.8 PVD34631.1 - 0.039 13.8 0.1 0.061 13.2 0.1 1.3 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF2771 PF10969.8 PVD34631.1 - 0.04 14.0 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) Insulin_TMD PF17870.1 PVD34631.1 - 0.049 13.7 3.4 0.079 13.0 3.4 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4834 PF16118.5 PVD34631.1 - 0.063 14.2 0.0 0.073 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4381 PF14316.6 PVD34631.1 - 0.1 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 PVD34631.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SIT PF15330.6 PVD34631.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Stevor PF17410.2 PVD34631.1 - 0.15 11.6 0.5 0.19 11.2 0.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TNFR_16_TM PF18422.1 PVD34631.1 - 0.23 11.5 2.7 0.33 10.9 2.7 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain GRA6 PF05084.13 PVD34631.1 - 1.5 8.7 5.0 1.5 8.7 0.8 2.0 1 1 1 2 2 2 0 Granule antigen protein (GRA6) Ion_trans PF00520.31 PVD34632.1 - 5.3e-28 97.9 7.5 9.1e-28 97.1 7.5 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 PVD34632.1 - 1.4e-27 95.6 1.0 3.6e-27 94.3 1.0 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 PVD34632.1 - 4.5e-12 46.4 1.0 1.1e-07 32.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34632.1 - 8.5e-12 45.4 0.0 6.4e-05 23.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 PVD34632.1 - 1.4e-10 40.4 4.8 1.1e-07 31.0 0.2 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_3 PF13606.6 PVD34632.1 - 4e-08 32.9 2.1 0.0072 16.8 0.1 4.4 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD34632.1 - 5.4e-06 26.6 0.6 0.41 11.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD34632.1 - 7.2e-06 26.2 0.3 0.23 11.8 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) E1_DerP2_DerF2 PF02221.15 PVD34633.1 - 3.3e-22 79.4 0.3 4.3e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 PVD34633.1 - 0.0071 16.8 0.1 0.046 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1091) Stanniocalcin PF03298.13 PVD34635.1 - 0.0019 17.5 0.1 0.035 13.4 0.0 2.3 2 0 0 2 2 2 1 Stanniocalcin family GRIN_C PF15235.6 PVD34635.1 - 0.037 14.2 0.2 8.8 6.6 0.1 2.4 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Proteasome_A_N PF10584.9 PVD34635.1 - 0.18 11.5 0.2 16 5.3 0.1 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TED_complement PF07678.14 PVD34639.1 - 1.2e-55 188.8 0.3 2.7e-29 102.2 0.1 3.4 1 1 2 3 3 3 3 A-macroglobulin TED domain MG2 PF01835.19 PVD34639.1 - 7.3e-18 64.8 1.6 7.6e-17 61.6 0.0 3.4 4 0 0 4 4 4 1 MG2 domain A2M_BRD PF07703.14 PVD34639.1 - 3.7e-16 59.8 1.4 1.4e-13 51.4 0.1 3.3 3 1 0 3 3 3 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD34639.1 - 3.9e-12 46.3 0.1 1.5e-11 44.4 0.1 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD34639.1 - 2.2e-08 34.1 1.4 3.3e-06 27.2 0.7 3.1 2 0 0 2 2 2 1 Macroglobulin domain MG4 A2M_recep PF07677.14 PVD34639.1 - 0.00056 20.6 0.0 0.0028 18.3 0.0 2.2 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain Big_1 PF02369.16 PVD34639.1 - 0.0094 15.9 1.0 0.11 12.5 1.0 3.0 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) MG3 PF17791.1 PVD34640.1 - 8.7e-13 48.4 0.1 1.8e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD34640.1 - 3.3e-06 27.5 0.0 9e-06 26.1 0.0 1.7 1 1 0 2 2 2 1 MG2 domain Big_1 PF02369.16 PVD34640.1 - 0.0055 16.7 1.0 0.017 15.1 1.0 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Chi-conotoxin PF16981.5 PVD34640.1 - 0.033 14.4 0.3 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily TED_complement PF07678.14 PVD34641.1 - 6.6e-51 173.2 0.0 1.2e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD34641.1 - 6.2e-26 91.4 5.8 1e-25 90.7 1.2 3.2 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD34641.1 - 3.4e-11 43.3 0.0 1.2e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 A2M PF00207.22 PVD34641.1 - 2.3e-06 27.3 5.8 8.7e-06 25.5 0.1 4.0 4 0 0 4 4 4 1 Alpha-2-macroglobulin family MG2 PF01835.19 PVD34641.1 - 7e-05 23.2 0.4 0.019 15.4 0.0 4.1 4 0 0 4 4 4 1 MG2 domain A2M_recep PF07677.14 PVD34641.1 - 0.0021 18.7 0.0 0.031 15.0 0.0 3.1 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain Big_1 PF02369.16 PVD34641.1 - 0.0061 16.5 0.8 0.13 12.3 0.4 3.5 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) DUF5575 PF17738.1 PVD34641.1 - 0.11 11.5 0.1 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5575) TED_complement PF07678.14 PVD34642.1 - 3.5e-81 272.6 0.1 6.1e-81 271.9 0.1 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain MG2 PF01835.19 PVD34642.1 - 1e-16 61.1 0.1 3.8e-15 56.1 0.0 3.4 3 0 0 3 3 3 1 MG2 domain A2M_BRD PF07703.14 PVD34642.1 - 3.2e-13 50.2 13.3 8.7e-13 48.8 0.9 4.6 4 1 0 4 4 4 2 Alpha-2-macroglobulin bait region domain A2M_recep PF07677.14 PVD34642.1 - 2.1e-11 44.4 0.1 2.1e-11 44.4 0.1 2.9 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain MG3 PF17791.1 PVD34642.1 - 3.8e-10 39.9 0.0 2e-09 37.6 0.0 2.4 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD34642.1 - 3.9e-06 26.9 1.2 6.7e-05 23.0 0.3 3.5 3 0 0 3 3 3 1 Macroglobulin domain MG4 A2M PF00207.22 PVD34642.1 - 7e-06 25.8 3.9 8e-06 25.6 0.4 3.0 3 0 0 3 3 3 1 Alpha-2-macroglobulin family SQHop_cyclase_C PF13243.6 PVD34642.1 - 0.0039 16.3 0.1 0.01 14.9 0.1 1.6 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Big_1 PF02369.16 PVD34642.1 - 0.59 10.2 8.5 0.069 13.2 0.9 3.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) TED_complement PF07678.14 PVD34643.1 - 4.7e-84 282.1 0.0 7.4e-84 281.4 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD34643.1 - 5.9e-21 75.3 2.1 5.9e-21 75.3 2.1 4.1 3 1 1 4 4 4 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD34643.1 - 9.3e-21 73.5 0.3 6.4e-20 70.8 0.1 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG2 PF01835.19 PVD34643.1 - 7.3e-16 58.4 0.0 5.3e-15 55.7 0.0 2.6 2 0 0 2 2 2 1 MG2 domain A2M_recep PF07677.14 PVD34643.1 - 1.8e-11 44.5 0.1 9.9e-11 42.2 0.1 2.4 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG3 PF17791.1 PVD34643.1 - 6e-10 39.3 0.0 2.5e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG3 A2M_BRD PF07703.14 PVD34644.1 - 4.4e-26 91.9 0.8 4.8e-23 82.1 0.4 3.2 2 1 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD34644.1 - 2.3e-15 56.2 2.4 7.7e-14 51.3 0.5 3.4 3 0 0 3 3 3 1 Alpha-2-macroglobulin family MG2 PF01835.19 PVD34644.1 - 2.9e-09 37.2 2.1 2.3e-07 31.1 0.0 4.5 5 0 0 5 5 5 1 MG2 domain MG3 PF17791.1 PVD34644.1 - 3e-07 30.6 0.5 2.7e-06 27.5 0.0 2.8 2 1 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD34644.1 - 0.00087 19.4 6.2 0.35 11.1 1.4 4.1 3 1 1 4 4 4 2 Macroglobulin domain MG4 Glyco_hydro_66 PF13199.6 PVD34644.1 - 0.014 14.1 0.1 0.052 12.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 Transglut_C PF00927.22 PVD34644.1 - 0.15 12.2 3.1 17 5.6 0.0 3.5 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain TED_complement PF07678.14 PVD34645.1 - 2.2e-39 135.3 1.9 2.7e-39 135.1 1.9 1.1 1 0 0 1 1 1 1 A-macroglobulin TED domain MG2 PF01835.19 PVD34646.1 - 4e-14 52.9 1.9 2e-11 44.2 0.0 3.9 3 1 0 3 3 3 1 MG2 domain A2M_BRD PF07703.14 PVD34646.1 - 7e-07 29.7 3.4 3.2e-05 24.3 0.5 3.5 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD34646.1 - 0.00022 21.0 6.6 0.00024 20.9 0.2 3.4 3 0 0 3 3 3 1 Alpha-2-macroglobulin family MG3 PF17791.1 PVD34646.1 - 0.0016 18.7 0.1 0.017 15.3 0.0 2.8 4 0 0 4 4 4 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD34646.1 - 0.006 16.7 4.0 0.14 12.3 1.0 3.4 1 1 2 3 3 3 1 Macroglobulin domain MG4 DUF3678 PF12435.8 PVD34647.1 - 0.039 13.3 4.3 0.039 13.3 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ank_2 PF12796.7 PVD34648.1 - 9.4e-69 228.0 0.6 1.1e-16 61.2 0.0 6.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 PVD34648.1 - 2.5e-60 204.4 0.0 6.3e-58 196.5 0.0 2.3 1 1 0 1 1 1 1 KAP family P-loop domain Ank_4 PF13637.6 PVD34648.1 - 4.7e-58 192.9 1.0 2.3e-10 40.8 0.0 8.2 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34648.1 - 1.6e-52 174.9 5.8 2.4e-07 30.9 0.1 9.5 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 PVD34648.1 - 4.7e-50 165.9 0.5 0.00025 21.3 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 PVD34648.1 - 4.2e-46 149.6 0.3 0.00072 19.8 0.0 11.8 11 0 0 11 11 11 11 Ankyrin repeat Motile_Sperm PF00635.26 PVD34649.1 - 2.1e-20 72.6 0.1 1.1e-19 70.3 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain CRAL_TRIO PF00650.20 PVD34649.1 - 3e-10 40.1 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Reeler PF02014.16 PVD34649.1 - 0.0016 19.2 0.5 0.0091 16.8 0.0 2.1 2 0 0 2 2 2 1 Reeler domain AnkUBD PF18418.1 PVD34650.1 - 0.14 12.4 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain Glyco_transf_10 PF00852.19 PVD34651.1 - 7.7e-53 178.8 3.0 1.3e-52 178.1 3.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD34651.1 - 1.3e-08 35.3 2.5 2e-08 34.6 0.3 2.5 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal CDP-OH_P_transf PF01066.21 PVD34652.1 - 0.015 16.0 2.2 0.039 14.7 0.3 2.4 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase LYTB PF02401.18 PVD34652.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 LytB protein CD36 PF01130.21 PVD34653.1 - 4.1e-148 493.8 0.5 5.2e-148 493.4 0.5 1.1 1 0 0 1 1 1 1 CD36 family Methyltransf_8 PF05148.15 PVD34653.1 - 1.3e-19 70.9 0.0 2.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Gal-bind_lectin PF00337.22 PVD34653.1 - 1.3e-06 28.0 0.1 2.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Galactoside-binding lectin Methyltransf_11 PF08241.12 PVD34653.1 - 0.00067 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 PVD34653.1 - 0.1 11.8 0.4 0.2 10.8 0.4 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family M3 PF09213.10 PVD34656.1 - 0.2 10.3 0.0 0.53 8.9 0.0 1.5 1 1 1 2 2 2 0 M3 NUDIX PF00293.28 PVD34657.1 - 0.0077 16.3 0.0 0.0091 16.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain FGF PF00167.18 PVD34659.1 - 5.4e-11 42.7 3.2 1e-09 38.5 0.4 2.8 2 1 1 3 3 3 1 Fibroblast growth factor Peptidase_S78 PF04586.17 PVD34659.1 - 0.095 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Caudovirus prohead serine protease DUF4992 PF16383.5 PVD34660.1 - 0.2 11.2 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function EF-hand_7 PF13499.6 PVD34661.1 - 8.5e-15 55.0 4.8 0.0009 19.7 0.7 5.4 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD34661.1 - 1.3e-12 46.6 4.9 0.00011 21.9 0.2 5.2 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 PVD34661.1 - 4.4e-12 44.6 14.1 3.9e-06 26.0 0.2 6.7 8 0 0 8 8 8 2 EF hand EF-hand_8 PF13833.6 PVD34661.1 - 4.6e-12 45.6 6.7 6.3e-07 29.2 0.0 5.7 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD34661.1 - 5.4e-08 32.0 7.1 2.6e-05 23.5 0.2 4.4 4 0 0 4 4 4 2 EF hand DUF4734 PF15881.5 PVD34661.1 - 0.07 13.3 1.2 7 6.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) PWWP PF00855.17 PVD34661.1 - 0.12 12.7 0.2 0.92 10.0 0.0 2.3 2 0 0 2 2 2 0 PWWP domain SNF2_N PF00176.23 PVD34662.1 - 3e-57 194.0 4.6 6.1e-57 192.9 4.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ADD_ATRX PF17981.1 PVD34662.1 - 1.8e-15 56.5 0.2 4.7e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 Cysteine Rich ADD domain Helicase_C PF00271.31 PVD34662.1 - 6.1e-12 45.9 0.0 3.5e-11 43.4 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD34662.1 - 9.5e-11 42.0 0.0 9.5e-11 42.0 0.0 4.5 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PVD34662.1 - 0.00087 19.1 0.3 0.0028 17.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase C5HCH PF17982.1 PVD34662.1 - 0.68 10.1 3.9 2.6 8.3 3.9 2.0 1 0 0 1 1 1 0 NSD Cys-His rich domain AAA_22 PF13401.6 PVD34662.1 - 1.2 9.4 4.0 0.66 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain Vpu PF00558.19 PVD34662.1 - 3.1 7.6 6.3 59 3.5 6.3 3.4 1 0 0 1 1 1 0 Vpu protein SLAIN PF15301.6 PVD34663.1 - 1.5e-22 80.5 31.9 1.3e-16 61.0 11.9 3.8 1 1 1 3 3 3 3 SLAIN motif-containing family bZIP_1 PF00170.21 PVD34663.1 - 0.2 11.8 5.5 0.87 9.7 4.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor Cadherin PF00028.17 PVD34665.1 - 1.1e-06 29.0 0.3 4.7e-05 23.7 0.1 2.5 2 1 0 2 2 2 1 Cadherin domain Cadherin_3 PF16184.5 PVD34665.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like FSAP_sig_propep PF03032.15 PVD34665.1 - 0.21 11.6 1.5 0.47 10.5 1.5 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Cadherin PF00028.17 PVD34666.1 - 1.8e-86 284.7 8.5 2.7e-19 69.4 0.0 6.6 6 1 1 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 PVD34666.1 - 1.9e-15 56.8 9.8 0.01 15.8 0.0 5.6 6 0 0 6 6 6 5 Cadherin-like Cadherin_pro PF08758.11 PVD34666.1 - 9.9e-07 28.8 0.2 0.2 11.8 0.0 3.9 4 0 0 4 4 4 2 Cadherin prodomain like Cadherin_4 PF17803.1 PVD34666.1 - 6.5e-05 23.5 41.0 0.005 17.4 1.9 6.0 6 1 0 6 6 6 4 Bacterial cadherin-like domain SusE PF14292.6 PVD34666.1 - 0.91 9.8 14.4 0.59 10.4 0.1 4.9 4 1 3 7 7 7 0 SusE outer membrane protein Cadherin PF00028.17 PVD34667.1 - 5.9e-56 186.9 0.4 3.1e-18 66.0 0.2 4.2 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 PVD34667.1 - 1.3e-05 25.0 0.0 1.7 8.5 0.0 4.1 4 0 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 PVD34667.1 - 0.0018 18.2 0.1 2 8.4 0.0 2.6 2 0 0 2 2 2 2 Cadherin-like Cadherin PF00028.17 PVD34669.1 - 6.4e-279 901.6 40.7 4.2e-22 78.4 0.0 20.2 18 2 2 20 20 20 19 Cadherin domain Laminin_G_2 PF02210.24 PVD34669.1 - 2.7e-21 76.5 0.1 2.8e-09 37.6 0.0 3.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD34669.1 - 9.4e-17 61.5 0.0 1.5e-08 34.9 0.0 3.2 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 PVD34669.1 - 6.3e-13 48.8 74.2 4.5e-07 30.0 8.4 7.3 7 0 0 7 7 7 5 EGF-like domain Cadherin_2 PF08266.12 PVD34669.1 - 1.9e-12 46.9 0.0 12 5.8 0.0 10.4 12 1 0 12 12 12 0 Cadherin-like Cadherin_3 PF16184.5 PVD34669.1 - 1.5e-08 34.7 32.4 4.7 7.2 0.0 13.8 16 0 0 16 16 15 2 Cadherin-like EGF_CA PF07645.15 PVD34669.1 - 8.5e-08 32.3 6.1 8.5e-08 32.3 6.1 5.3 4 1 1 5 5 3 1 Calcium-binding EGF domain Cadherin_pro PF08758.11 PVD34669.1 - 1e-06 28.8 0.0 0.0047 17.1 0.0 5.4 7 0 0 7 7 7 1 Cadherin prodomain like hEGF PF12661.7 PVD34669.1 - 0.00022 21.7 66.1 0.00053 20.5 7.5 7.1 7 0 0 7 7 6 4 Human growth factor-like EGF EGF_3 PF12947.7 PVD34669.1 - 0.00066 19.8 3.7 0.00066 19.8 3.7 4.4 5 0 0 5 5 2 2 EGF domain GP40 PF11025.8 PVD34669.1 - 0.017 14.9 0.1 0.091 12.5 0.1 2.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF3377 PF11857.8 PVD34669.1 - 0.042 13.8 2.4 0.14 12.1 2.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) S1FA PF04689.13 PVD34669.1 - 0.048 13.8 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 DNA binding protein S1FA Insulin_TMD PF17870.1 PVD34669.1 - 0.87 9.7 10.8 2.8 8.1 10.8 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 PVD34669.1 - 7.5 6.5 5.9 17 5.4 5.9 1.5 1 0 0 1 1 1 0 Syndecan domain baeRF_family10 PF18854.1 PVD34670.1 - 0.031 14.5 1.8 0.062 13.5 1.8 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 BALF1 PF06861.11 PVD34670.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 BALF1 protein PHD_2 PF13831.6 PVD34671.1 - 1.3 8.6 23.9 0.34 10.5 11.2 3.4 3 0 0 3 3 3 0 PHD-finger RVT_1 PF00078.27 PVD34672.1 - 1.8e-51 174.8 0.2 3.2e-51 174.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PVD34673.1 - 7.1e-18 64.6 0.0 1.9e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD34673.1 - 9.6e-13 48.2 0.3 1.7e-12 47.4 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MutS_IV PF05190.18 PVD34673.1 - 0.029 14.7 0.1 0.065 13.6 0.1 1.6 1 0 0 1 1 1 0 MutS family domain IV DUF1932 PF09130.11 PVD34673.1 - 0.064 13.2 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Streptin-Immun PF11083.8 PVD34673.1 - 0.15 12.5 0.3 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein zf-C2H2_jaz PF12171.8 PVD34674.1 - 0.0038 17.5 0.7 0.0038 17.5 0.7 7.5 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 PVD34674.1 - 0.0043 17.1 0.3 0.0043 17.1 0.3 7.5 7 1 0 7 7 7 2 Zinc ribbon domain zf-C2H2 PF00096.26 PVD34674.1 - 0.015 15.7 3.4 0.019 15.4 2.1 14.8 17 0 0 17 17 17 0 Zinc finger, C2H2 type zf-CSL PF05207.13 PVD34674.1 - 0.04 13.6 0.4 0.04 13.6 0.4 4.4 6 0 0 6 6 6 0 CSL zinc finger HypA PF01155.19 PVD34674.1 - 0.047 13.7 0.3 0.047 13.7 0.3 6.8 7 1 1 8 8 8 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 PVD34674.1 - 0.2 12.6 0.1 0.079 13.8 1.8 16.1 17 0 0 17 17 17 0 C2H2-type zinc finger GDWWSH PF15667.5 PVD34676.1 - 0.043 13.2 4.3 0.027 13.9 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function with motif GDWWSH RhoGAP PF00620.27 PVD34678.1 - 4.1e-38 130.6 0.0 9.7e-38 129.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain 7tm_1 PF00001.21 PVD34679.1 - 5.9e-13 48.8 14.7 8.9e-13 48.2 14.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUB PF00431.20 PVD34679.1 - 3.2e-05 24.2 0.0 6.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 CUB domain 7TM_GPCR_Srw PF10324.9 PVD34679.1 - 0.0007 19.0 8.2 0.0025 17.1 8.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 PVD34679.1 - 0.0076 16.0 3.0 0.013 15.3 3.0 1.3 1 0 0 1 1 1 1 Olfactory receptor Peptidase_C1 PF00112.23 PVD34680.1 - 6.6e-58 196.4 1.4 8.7e-58 196.0 1.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD34680.1 - 4e-10 40.0 5.7 4e-10 40.0 5.7 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD34680.1 - 1.2e-06 27.5 0.1 0.045 12.5 0.0 2.5 3 0 0 3 3 3 2 Peptidase C1-like family KH_2 PF07650.17 PVD34681.1 - 2.5e-11 43.2 0.1 3.8e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 KH domain Ribosomal_S3_C PF00189.20 PVD34681.1 - 0.00025 21.5 0.0 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain NDK PF00334.19 PVD34682.1 - 8.3e-35 119.7 0.0 3e-22 79.1 0.0 2.0 1 1 1 2 2 2 2 Nucleoside diphosphate kinase Ank_2 PF12796.7 PVD34683.1 - 6.1e-40 135.7 5.5 3.6e-13 49.9 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34683.1 - 1.2e-31 108.7 2.0 2.7e-08 34.2 0.2 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD34683.1 - 5.8e-30 103.0 2.2 5e-08 33.1 0.0 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34683.1 - 2.7e-29 98.0 0.6 0.00053 20.2 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 PVD34683.1 - 6.6e-27 92.8 8.4 4e-05 23.9 0.1 6.7 7 0 0 7 7 7 5 Ankyrin repeat CTXphi_pIII-N1 PF16710.5 PVD34683.1 - 0.054 13.6 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Orthopox_F14 PF06076.12 PVD34683.1 - 0.079 13.2 0.2 33 4.9 0.0 3.4 3 1 0 3 3 3 0 Orthopoxvirus F14 protein Asparaginase_2 PF01112.18 PVD34684.1 - 8.5e-65 218.8 0.4 1.2e-63 215.1 0.4 1.9 1 1 0 1 1 1 1 Asparaginase Glyco_trans_2_3 PF13632.6 PVD34685.1 - 1.2e-33 116.7 3.4 1.2e-33 116.7 3.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD34685.1 - 6.4e-09 36.0 0.0 8.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PVD34685.1 - 0.025 14.1 0.0 0.061 12.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 MIF PF01187.18 PVD34686.1 - 2.8e-10 40.5 0.1 2.2e-09 37.6 0.1 1.9 1 1 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Retinin_C PF04527.12 PVD34687.1 - 0.096 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Drosophila Retinin like protein IRK_N PF08466.10 PVD34688.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal SNF PF00209.18 PVD34689.1 - 4.4e-60 203.9 22.5 6.2e-55 186.9 17.9 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family PrgI PF12666.7 PVD34689.1 - 3 8.6 8.9 1.4 9.7 2.4 2.9 2 0 0 2 2 2 0 PrgI family protein SNF PF00209.18 PVD34690.1 - 1.1e-153 512.7 35.6 3.3e-122 408.8 18.2 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family SNF PF00209.18 PVD34691.1 - 3.5e-209 695.8 40.6 4.8e-206 685.5 40.6 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Myelin_PLP PF01275.19 PVD34692.1 - 9.2e-43 146.8 16.7 1.1e-42 146.5 16.7 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Glycos_transf_2 PF00535.26 PVD34693.1 - 7.8e-31 107.2 0.0 1.3e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 PVD34693.1 - 3.5e-26 92.0 0.2 5.2e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 PVD34693.1 - 2.3e-06 27.2 0.5 8.3e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PVD34693.1 - 0.0017 17.9 0.0 0.0048 16.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 PVD34693.1 - 0.0091 15.6 0.0 0.072 12.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_3 PF13641.6 PVD34693.1 - 0.0099 15.8 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 ACI44 PF15270.6 PVD34693.1 - 0.054 13.7 0.4 0.17 12.1 0.2 1.9 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor PH PF00169.29 PVD34694.1 - 5.8e-16 58.9 0.2 1.1e-15 58.0 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD34694.1 - 0.041 14.3 0.3 0.72 10.3 0.3 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_C2 PF00648.21 PVD34695.1 - 4.1e-68 229.6 0.0 6.2e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease ING PF12998.7 PVD34696.1 - 7.5e-20 71.4 0.3 7.5e-20 71.4 0.3 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding CCDC53 PF10152.9 PVD34696.1 - 0.042 14.3 7.9 0.064 13.7 7.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SWIRM-assoc_2 PF16496.5 PVD34696.1 - 0.83 8.5 15.2 1.1 8.0 15.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RR_TM4-6 PF06459.12 PVD34696.1 - 5 6.9 12.9 7.1 6.4 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 tRNA-synt_1e PF01406.19 PVD34697.1 - 7.4e-113 376.9 0.2 9.8e-113 376.5 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PVD34697.1 - 9.9e-11 41.0 1.7 6.9e-06 25.1 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PVD34697.1 - 2.2e-05 22.9 0.0 0.00019 19.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Ten1 PF12658.7 PVD34697.1 - 0.019 14.9 0.1 0.7 9.9 0.0 2.9 3 0 0 3 3 3 0 Telomere capping, CST complex subunit DALR_2 PF09190.11 PVD34697.1 - 0.033 14.7 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 DALR domain STD1 PF17235.2 PVD34697.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 STD1/MTH1 tRNA-synt_1f PF01921.18 PVD34697.1 - 0.13 11.1 0.7 0.77 8.6 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) KIAA1430 PF13879.6 PVD34698.1 - 1.1e-09 38.9 7.8 1.1e-09 38.9 7.8 3.7 2 2 0 2 2 2 1 KIAA1430 homologue Spore_YhaL PF14147.6 PVD34698.1 - 0.074 12.8 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL zf-C2H2_jaz PF12171.8 PVD34700.1 - 8.2e-07 29.2 1.5 8.2e-07 29.2 1.5 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD34700.1 - 1.5e-06 28.4 1.4 2.6e-06 27.6 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 PVD34700.1 - 0.00045 19.9 1.1 0.00045 19.9 1.1 1.7 2 0 0 2 2 2 1 U1 zinc finger SNRNP27 PF08648.12 PVD34700.1 - 0.0044 17.1 0.2 0.0044 17.1 0.2 3.0 2 1 2 4 4 4 1 U4/U6.U5 small nuclear ribonucleoproteins NARP1 PF12569.8 PVD34700.1 - 0.03 13.2 10.5 0.044 12.7 10.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.10 PVD34700.1 - 0.12 12.6 22.3 0.024 15.0 18.6 1.6 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 zf-C2H2 PF00096.26 PVD34700.1 - 0.13 12.8 1.0 0.27 11.8 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PPL5 PF18168.1 PVD34700.1 - 0.69 9.2 8.3 0.95 8.7 8.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Neur_chan_memb PF02932.16 PVD34700.1 - 0.73 9.8 2.8 1.2 9.2 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 PVD34700.1 - 1.3 8.4 5.0 1.9 7.7 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vma12 PF11712.8 PVD34700.1 - 2.8 8.0 7.0 20 5.2 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Presenilin PF01080.17 PVD34700.1 - 3.6 6.2 6.4 5.1 5.8 6.4 1.2 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 PVD34700.1 - 7.6 6.4 27.1 0.43 10.4 19.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Sec62 PF03839.16 PVD34700.1 - 9.6 5.6 9.8 17 4.9 9.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 EMC3_TMCO1 PF01956.16 PVD34700.1 - 9.6 5.9 11.5 16 5.2 11.5 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3340 PF11818.8 PVD34701.1 - 0.37 10.9 6.1 0.55 10.4 6.1 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF719 PF05334.13 PVD34702.1 - 1.3e-34 120.0 14.8 1.3e-34 120.0 14.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF719) SNAD3 PF18749.1 PVD34702.1 - 0.055 12.6 2.5 0.075 12.2 2.0 1.4 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Rota_NSP4 PF01452.16 PVD34702.1 - 0.056 13.1 0.5 0.7 9.5 0.2 2.2 2 0 0 2 2 2 0 Rotavirus non structural protein DUF725 PF05267.12 PVD34702.1 - 0.091 12.7 1.0 8.3 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Nucleoporin_FG2 PF15967.5 PVD34703.1 - 1.6e-81 274.7 46.9 5.4e-80 269.6 46.9 2.2 1 1 0 1 1 1 1 Nucleoporin FG repeated region P4Ha_N PF08336.11 PVD34703.1 - 0.18 11.8 3.0 0.38 10.8 0.3 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.10 PVD34703.1 - 0.26 11.5 1.6 0.86 9.8 1.2 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 PVD34703.1 - 0.39 10.5 3.3 0.47 10.3 0.9 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4600 PF15372.6 PVD34703.1 - 1.3 9.4 5.1 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Myotub-related PF06602.14 PVD34706.1 - 2.1e-141 470.9 0.1 2.7e-141 470.6 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 PVD34706.1 - 8.8e-05 22.3 0.1 0.00021 21.1 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PVD34706.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2824 PF11039.8 PVD34706.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Y_phosphatase3 PF13350.6 PVD34706.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family FA_hydroxylase PF04116.13 PVD34707.1 - 3.9e-22 79.0 18.2 4.2e-22 78.9 16.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 PVD34708.1 - 2.1e-16 60.4 20.6 4.4e-16 59.4 20.6 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily SprT-like PF10263.9 PVD34708.1 - 8.9e-11 41.7 0.1 2.6e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 PVD34708.1 - 7.9e-05 22.5 3.2 0.00022 21.0 3.2 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Herpes_capsid PF06112.11 PVD34709.1 - 0.0015 18.7 0.3 0.0029 17.7 0.3 1.4 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein STELLO PF03385.17 PVD34709.1 - 0.02 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases DUF4596 PF15363.6 PVD34709.1 - 0.71 10.1 2.7 1.2 9.4 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4596) Carb_anhydrase PF00194.21 PVD34710.1 - 6.2e-30 104.6 0.0 8.6e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Sushi_2 PF09014.10 PVD34710.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Carb_anhydrase PF00194.21 PVD34711.1 - 8.7e-21 74.6 0.1 6.2e-20 71.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase vWF_A PF12450.8 PVD34712.1 - 0.0085 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor Torsin PF06309.11 PVD34714.1 - 3.1e-44 150.1 0.6 7.2e-44 149.0 0.6 1.6 1 0 0 1 1 1 1 Torsin UQ_con PF00179.26 PVD34714.1 - 4.5e-05 23.1 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA PF00004.29 PVD34714.1 - 0.0026 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD34714.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD34714.1 - 0.012 15.8 0.3 0.22 11.8 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 PVD34714.1 - 0.022 14.9 0.1 0.14 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.18 PVD34714.1 - 0.099 12.5 0.9 0.38 10.6 0.2 2.0 1 1 1 2 2 2 0 Bacterial dnaA protein DUF4110 PF13422.6 PVD34714.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Pribosyl_synth PF14572.6 PVD34715.1 - 1.5e-44 152.2 1.8 5.5e-38 130.8 1.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 PVD34715.1 - 7.2e-39 132.3 0.8 8.8e-38 128.8 0.0 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 PVD34715.1 - 7e-15 54.9 1.0 1.1e-14 54.3 0.5 1.6 1 1 1 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PVD34715.1 - 2.3e-06 27.2 0.2 3.8e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Myotub-related PF06602.14 PVD34717.1 - 6.3e-152 505.6 0.2 9.7e-152 504.9 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 PVD34717.1 - 1.8e-14 53.6 0.0 3.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 PVD34717.1 - 0.00013 21.7 0.4 0.00025 20.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 PVD34717.1 - 0.00014 21.7 0.0 0.00048 20.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD34717.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family 3-PAP PF12578.8 PVD34717.1 - 0.044 13.5 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 Myotubularin-associated protein Ferrochelatase PF00762.19 PVD34718.1 - 0.033 13.3 1.3 1.1 8.2 0.0 2.3 1 1 1 2 2 2 0 Ferrochelatase Mad3_BUB1_I PF08311.12 PVD34718.1 - 0.34 10.9 2.5 9.4 6.2 1.5 3.1 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 PVD34718.1 - 2.1 9.4 8.6 12 7.1 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 PVD34720.1 - 1.4e-25 89.1 32.5 0.0002 22.1 0.0 12.5 11 3 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD34720.1 - 1.2e-18 67.2 9.4 0.0029 17.9 0.1 7.8 6 2 2 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.6 PVD34721.1 - 2.1e-29 100.6 28.3 5.7e-06 26.5 1.2 8.6 7 1 1 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 PVD34721.1 - 3.3e-20 71.3 54.7 1.2e-05 25.5 3.9 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD34721.1 - 7.5e-16 57.5 51.1 0.026 15.3 2.0 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD34721.1 - 1.9e-07 30.7 0.4 1.9e-07 30.7 0.4 7.5 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 PVD34721.1 - 2e-07 31.2 40.6 0.023 15.0 0.1 5.5 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PVD34721.1 - 3.6e-05 23.6 0.2 3.6e-05 23.6 0.2 7.2 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD34721.1 - 0.00056 19.6 1.6 0.00056 19.6 1.6 4.0 6 0 0 6 6 6 1 zinc-finger C2H2-type ROS_MUCR PF05443.11 PVD34721.1 - 0.059 13.4 0.3 2.2 8.3 0.1 3.0 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Methyltransf_32 PF13679.6 PVD34722.1 - 1.2e-13 51.3 5.8 2.9e-06 27.4 3.9 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PVD34722.1 - 8.8e-08 32.1 0.1 2.7e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 PVD34722.1 - 1.9e-06 27.6 3.3 0.00055 19.5 3.1 2.9 1 1 1 2 2 2 2 Methyltransferase TRM13 MTS PF05175.14 PVD34722.1 - 0.00016 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 PVD34722.1 - 0.003 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 PVD34722.1 - 0.0044 17.7 0.1 0.015 16.0 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD34722.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase GST_C_3 PF14497.6 PVD34722.1 - 0.038 14.2 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.9 PVD34722.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Pan3_PK PF18101.1 PVD34723.1 - 2.3e-62 209.1 0.1 3.5e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain zf-CCCH PF00642.24 PVD34723.1 - 8.2e-08 32.0 1.5 1.6e-07 31.0 1.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD34723.1 - 1.5e-07 31.2 4.1 3e-07 30.3 4.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PVD34723.1 - 1.5e-05 24.6 1.9 2.9e-05 23.8 1.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Pkinase PF00069.25 PVD34723.1 - 0.00059 19.3 0.0 0.012 15.0 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain zf-CCCH_2 PF14608.6 PVD34723.1 - 0.0012 19.3 2.4 0.0026 18.2 2.4 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PVD34723.1 - 0.013 16.2 0.3 0.024 15.3 0.3 1.4 1 0 0 1 1 1 0 Torus domain E1_DerP2_DerF2 PF02221.15 PVD34726.1 - 2.7e-06 27.9 0.0 5.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 ML domain DUF104 PF01954.16 PVD34727.1 - 0.041 14.3 1.1 0.057 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF104 Phage_int_SAM_3 PF14659.6 PVD34727.1 - 0.12 12.7 1.5 0.21 11.9 0.4 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain MMR_HSR1 PF01926.23 PVD34728.1 - 3.2e-17 62.6 0.0 4.3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD34728.1 - 2.6e-08 34.0 0.0 0.00022 21.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PVD34728.1 - 6.3e-08 32.3 0.0 9.5e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD34728.1 - 3.7e-06 26.6 0.0 6.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PVD34728.1 - 0.0005 20.2 0.0 0.63 10.1 0.2 2.1 1 1 1 2 2 2 2 Dynamin family ATP_bind_1 PF03029.17 PVD34728.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 PVD34728.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Pkinase_Tyr PF07714.17 PVD34729.1 - 2.8e-39 135.0 0.1 8.7e-36 123.5 0.0 3.5 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PVD34729.1 - 3e-29 102.2 0.1 1.3e-25 90.3 0.0 3.2 1 1 1 2 2 2 2 Protein kinase domain SAM_1 PF00536.30 PVD34729.1 - 2.8e-09 37.3 0.0 9.8e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD34729.1 - 1e-07 32.0 0.0 3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PRIMA1 PF16101.5 PVD34729.1 - 0.2 11.7 5.3 0.57 10.2 5.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 COR PF16095.5 PVD34730.1 - 2.7e-50 170.9 2.9 3.2e-50 170.7 0.9 2.3 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain Roc PF08477.13 PVD34730.1 - 5.1e-22 78.3 0.0 1.6e-21 76.7 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SPRY PF00622.28 PVD34730.1 - 1.9e-18 66.7 2.7 4.2e-10 39.8 0.1 4.9 4 0 0 4 4 4 3 SPRY domain LRR_8 PF13855.6 PVD34730.1 - 7.4e-18 64.1 8.9 4.9e-07 29.4 0.1 5.0 3 1 1 4 4 4 2 Leucine rich repeat TIR_2 PF13676.6 PVD34730.1 - 4.1e-15 56.4 0.1 1.1e-08 35.6 0.0 3.4 2 0 0 2 2 2 2 TIR domain Ras PF00071.22 PVD34730.1 - 1.5e-09 37.6 0.0 5e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.7 PVD34730.1 - 2.3e-09 37.4 16.0 0.001 19.4 2.1 5.5 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD34730.1 - 4.5e-05 23.3 3.9 0.00023 21.0 0.0 3.1 3 0 0 3 3 3 1 TIR domain ABC_tran PF00005.27 PVD34730.1 - 0.021 15.3 1.6 0.051 14.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 PVD34730.1 - 0.033 13.6 0.1 0.12 11.8 0.1 2.0 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD34730.1 - 0.15 12.2 0.4 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ANF_receptor PF01094.28 PVD34731.1 - 1.7e-37 129.4 0.0 2.8e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34731.1 - 1.4e-05 24.9 0.1 0.00018 21.3 0.1 2.0 2 0 0 2 2 2 1 Periplasmic binding protein Shisa PF13908.6 PVD34731.1 - 0.048 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 PVD34731.1 - 0.13 13.2 0.0 0.27 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 PVD34731.1 - 0.17 12.9 0.0 0.36 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ANF_receptor PF01094.28 PVD34732.1 - 1.5e-18 67.0 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34732.1 - 0.00054 19.7 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 PVD34734.1 - 9.4e-63 212.4 1.4 6e-32 111.1 0.0 3.3 3 0 0 3 3 3 3 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34734.1 - 1.3e-06 28.3 3.0 0.00037 20.3 1.5 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Citrate_synt PF00285.21 PVD34734.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain HATPase_c_3 PF13589.6 PVD34735.1 - 0.0042 16.9 0.1 3.7 7.4 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PVD34736.1 - 0.017 14.9 0.0 0.23 11.3 0.0 2.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN PF05168.14 PVD34737.1 - 1.4e-15 57.5 0.0 8.3e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 HEPN domain DnaJ PF00226.31 PVD34737.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain SR-25 PF10500.9 PVD34737.1 - 0.11 12.0 6.5 0.25 10.9 6.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CheY-binding PF09078.11 PVD34738.1 - 0.029 14.5 0.3 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 CheY binding HEPN PF05168.14 PVD34739.1 - 5.2e-17 62.1 0.0 3.7e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 HEPN domain HATPase_c_3 PF13589.6 PVD34739.1 - 6.8e-05 22.7 0.5 0.98 9.3 0.0 3.9 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SR-25 PF10500.9 PVD34739.1 - 0.056 13.0 9.9 0.12 12.0 9.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANF_receptor PF01094.28 PVD34740.1 - 8e-46 156.7 0.1 5e-33 114.7 0.1 3.0 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34740.1 - 1.6e-07 31.3 0.1 0.011 15.5 0.0 3.3 3 0 0 3 3 3 2 Periplasmic binding protein SKG6 PF08693.10 PVD34740.1 - 0.0085 15.5 2.7 0.021 14.2 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BBS2_N PF14781.6 PVD34740.1 - 0.028 14.3 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal ANF_receptor PF01094.28 PVD34741.1 - 3.8e-37 128.2 0.4 1.1e-21 77.3 0.0 3.0 3 0 0 3 3 3 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD34741.1 - 6.1e-09 36.0 0.2 0.00046 20.0 0.1 2.5 2 1 0 2 2 2 2 Periplasmic binding protein LRR_6 PF13516.6 PVD34743.1 - 6.9e-22 75.6 19.5 0.00014 21.7 0.1 8.0 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 PVD34743.1 - 0.0025 18.1 10.4 2 9.3 0.4 5.8 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 PVD34743.1 - 0.012 16.0 13.5 0.2 12.2 1.1 5.1 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD34743.1 - 0.2 11.4 16.6 0.38 10.6 7.0 4.7 5 1 1 6 6 6 0 Leucine rich repeat DUF4177 PF13783.6 PVD34745.1 - 1.1e-05 25.7 0.1 0.16 12.2 0.0 4.2 4 1 0 4 4 4 2 Domain of unknown function (DUF4177) Raftlin PF15250.6 PVD34745.1 - 0.0021 16.9 0.0 0.03 13.1 0.0 2.7 3 1 1 4 4 4 1 Raftlin AnmK PF03702.14 PVD34746.1 - 1.7e-60 205.1 0.0 1.1e-44 153.1 0.0 2.0 2 0 0 2 2 2 2 Anhydro-N-acetylmuramic acid kinase PDZ_assoc PF10600.9 PVD34746.1 - 0.058 14.2 5.3 0.13 13.1 5.3 1.6 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors zf-AN1 PF01428.16 PVD34748.1 - 1.5e-23 82.7 34.8 3.1e-12 46.5 13.8 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger UIM PF02809.20 PVD34748.1 - 0.0042 16.9 10.7 0.12 12.3 0.0 3.1 2 1 1 3 3 3 2 Ubiquitin interaction motif Transp_Tc5_C PF04236.15 PVD34748.1 - 0.018 15.4 19.0 0.47 10.9 5.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Pro_isomerase PF00160.21 PVD34749.1 - 2.1e-51 174.3 0.1 3.9e-51 173.5 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ PF00595.24 PVD34749.1 - 1.4e-17 63.8 0.0 2.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain TPR_2 PF07719.17 PVD34749.1 - 1.3e-12 46.7 7.7 1.1e-06 28.3 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD34749.1 - 2.2e-11 43.0 9.3 7.4e-06 25.6 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD34749.1 - 1.1e-08 35.6 1.1 9.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat PDZ_6 PF17820.1 PVD34749.1 - 3.5e-07 29.9 0.0 8.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain TPR_8 PF13181.6 PVD34749.1 - 2.3e-06 27.4 8.8 0.00024 21.1 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD34749.1 - 3.5e-06 27.2 2.2 0.0003 21.0 2.2 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD34749.1 - 3.8e-06 27.3 0.4 3.8e-06 27.3 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD34749.1 - 5.9e-06 26.0 0.3 0.00018 21.3 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD34749.1 - 1.5e-05 25.4 0.6 0.0045 17.7 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD34749.1 - 1.5e-05 24.5 7.1 0.028 14.1 0.2 3.5 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 PVD34749.1 - 7.9e-05 23.0 2.9 0.0059 17.2 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat PDZ_2 PF13180.6 PVD34749.1 - 0.0002 21.6 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain SRP_TPR_like PF17004.5 PVD34749.1 - 0.0012 18.9 0.8 0.0026 17.8 0.8 1.5 1 0 0 1 1 1 1 Putative TPR-like repeat Fis1_TPR_C PF14853.6 PVD34749.1 - 0.0038 17.3 1.2 0.47 10.6 0.1 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 PVD34749.1 - 0.018 15.2 0.1 0.06 13.5 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD34749.1 - 0.022 15.0 4.8 0.058 13.6 0.8 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PVD34749.1 - 0.043 13.0 0.4 0.12 11.6 0.4 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD34749.1 - 0.053 13.4 2.6 0.2 11.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_5 PF01795.19 PVD34749.1 - 0.06 12.9 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family TPR_3 PF07720.12 PVD34749.1 - 0.065 13.2 1.5 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PVD34749.1 - 0.093 13.1 0.4 2.2 8.9 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD34749.1 - 0.1 12.3 4.5 3 7.5 0.3 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 PVD34749.1 - 0.19 11.1 2.5 11 5.4 0.6 2.3 1 1 1 2 2 2 0 Coatomer epsilon subunit HemY_N PF07219.13 PVD34749.1 - 0.39 11.0 2.7 3.9 7.7 0.1 2.3 1 1 1 2 2 2 0 HemY protein N-terminus 7tm_1 PF00001.21 PVD34752.1 - 2e-13 50.3 5.4 2e-13 50.3 5.4 2.5 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DHHC PF01529.20 PVD34752.1 - 0.055 13.6 0.4 0.055 13.6 0.4 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase Pentapeptide_4 PF13599.6 PVD34753.1 - 9.7e-38 128.2 69.0 0.00014 22.0 1.7 12.3 1 1 10 11 11 11 11 Pentapeptide repeats (9 copies) Com_YlbF PF06133.11 PVD34753.1 - 0.057 14.0 46.4 2.9 8.5 3.5 7.2 2 2 3 6 6 6 0 Control of competence regulator ComK, YlbF/YmcA HC2 PF07382.11 PVD34753.1 - 0.36 10.9 62.2 2 8.5 10.9 4.4 1 1 2 4 4 4 0 Histone H1-like nucleoprotein HC2 COX_ARM PF06481.14 PVD34754.1 - 0.0053 16.6 19.7 30 4.6 0.0 12.4 10 1 0 10 10 10 4 COX Aromatic Rich Motif Beta-lactamase PF00144.24 PVD34755.1 - 6e-57 193.4 0.1 1e-56 192.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 PVD34755.1 - 0.025 15.0 0.1 0.12 12.9 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3471) Beta-lactamase PF00144.24 PVD34756.1 - 8e-16 58.2 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD34757.1 - 8.1e-28 97.6 0.5 1.4e-27 96.9 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 PVD34757.1 - 0.00032 21.1 0.0 0.00078 19.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) VCX_VCY PF15231.6 PVD34757.1 - 0.1 13.3 2.3 0.49 11.1 1.1 2.2 1 1 1 2 2 2 0 Variable charge X/Y family RhoGEF PF00621.20 PVD34758.1 - 4e-36 125.0 4.9 8.8e-36 123.8 2.2 2.5 2 0 0 2 2 2 1 RhoGEF domain WD40_like PF17005.5 PVD34758.1 - 0.03 13.7 0.0 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain TT_ORF2 PF02957.15 PVD34758.1 - 0.32 11.9 4.3 30 5.5 0.0 3.3 2 0 0 2 2 2 0 TT viral ORF2 dCMP_cyt_deam_1 PF00383.23 PVD34759.1 - 4.1e-09 36.2 0.0 4.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PVD34759.1 - 0.029 14.1 0.0 0.035 13.9 0.0 1.3 1 1 0 1 1 1 0 MafB19-like deaminase RR_TM4-6 PF06459.12 PVD34759.1 - 0.038 13.8 8.4 0.037 13.8 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 PVD34759.1 - 0.06 13.4 21.1 0.09 12.9 21.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Eapp_C PF10238.9 PVD34759.1 - 0.38 10.8 9.5 0.67 10.0 9.5 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Presenilin PF01080.17 PVD34759.1 - 0.53 9.0 6.5 0.59 8.8 6.5 1.1 1 0 0 1 1 1 0 Presenilin Afi1 PF07792.12 PVD34759.1 - 1.7 9.1 5.9 2.9 8.4 5.9 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 PVD34759.1 - 1.7 7.3 14.3 2.2 7.0 14.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.16 PVD34759.1 - 1.8 7.8 21.7 2.4 7.4 21.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FancD2 PF14631.6 PVD34759.1 - 2.5 5.4 8.4 3 5.1 8.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DDRGK PF09756.9 PVD34759.1 - 3.6 7.2 25.4 6.1 6.4 25.4 1.3 1 0 0 1 1 1 0 DDRGK domain RPN2_C PF18004.1 PVD34759.1 - 3.8 7.4 20.2 6.6 6.6 20.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 PVD34759.1 - 3.8 6.6 3.6 4.5 6.4 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 PVD34759.1 - 3.9 5.6 13.3 4.4 5.5 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 PVD34759.1 - 4.1 5.7 23.2 0.25 9.7 18.5 1.4 2 0 0 2 2 2 0 Mpp10 protein NARP1 PF12569.8 PVD34759.1 - 6.7 5.5 19.1 8.5 5.2 19.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 V_ATPase_I PF01496.19 PVD34759.1 - 7 4.4 9.6 8.6 4.1 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 PVD34759.1 - 9.1 5.9 10.3 17 5.1 10.3 1.4 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 PVD34759.1 - 9.3 5.0 9.2 9.6 4.9 9.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 dCMP_cyt_deam_1 PF00383.23 PVD34760.1 - 1.3e-09 37.9 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Myosin_head PF00063.21 PVD34762.1 - 1.8e-48 165.3 0.1 2.5e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 PVD34762.1 - 2.4e-35 121.3 0.9 7.8e-19 68.2 0.1 2.9 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 PVD34762.1 - 7.4e-07 29.6 0.1 0.00077 19.9 0.0 2.5 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.10 PVD34762.1 - 6.6e-06 26.0 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.27 PVD34762.1 - 0.00065 19.3 24.3 0.066 13.0 0.4 5.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif PTB PF08416.13 PVD34762.1 - 0.012 15.8 0.0 0.045 13.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Myosin_head PF00063.21 PVD34763.1 - 4.2e-155 517.7 14.1 2e-102 343.6 2.3 2.8 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 PVD34763.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PVD34763.1 - 0.015 15.8 0.9 0.034 14.7 0.2 2.0 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 PVD34763.1 - 0.02 14.1 0.3 0.059 12.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 PVD34763.1 - 0.031 14.7 0.0 0.069 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PVD34763.1 - 0.036 14.0 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase LRR_6 PF13516.6 PVD34764.1 - 5.1e-18 63.5 23.0 0.067 13.3 0.2 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 PVD34764.1 - 4.4e-07 29.6 11.8 8.1 7.4 0.0 7.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 PVD34764.1 - 1.1e-05 25.1 17.6 0.016 15.0 1.9 5.6 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PVD34764.1 - 4.1e-05 23.9 22.0 0.014 15.8 2.3 5.5 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) DUF2780 PF11075.8 PVD34764.1 - 0.053 13.7 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) AAA PF00004.29 PVD34765.1 - 4.1e-78 260.2 0.0 5.7e-43 146.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD34765.1 - 2.6e-22 78.3 3.3 5.8e-13 48.4 0.3 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 PVD34765.1 - 3.1e-10 40.0 0.0 0.001 18.8 0.0 3.9 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PVD34765.1 - 2.3e-09 37.9 0.1 0.00063 20.2 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 PVD34765.1 - 1.8e-08 34.4 0.1 0.0028 17.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PVD34765.1 - 6.1e-08 32.8 0.0 6.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 PVD34765.1 - 2.2e-07 30.4 0.0 0.008 15.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 PVD34765.1 - 3.4e-07 30.6 1.0 0.006 16.9 0.2 4.1 2 2 1 3 3 3 1 AAA domain AAA_25 PF13481.6 PVD34765.1 - 5.5e-07 29.4 0.9 1.1 8.9 0.1 3.9 2 2 1 3 3 3 3 AAA domain AAA_33 PF13671.6 PVD34765.1 - 1.6e-06 28.3 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PVD34765.1 - 2.2e-06 27.5 0.0 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 PVD34765.1 - 3.9e-06 26.4 0.5 0.069 12.5 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PVD34765.1 - 7.7e-06 26.3 0.0 0.072 13.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_2 PF07724.14 PVD34765.1 - 1.1e-05 25.7 0.0 0.17 12.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 PVD34765.1 - 2e-05 24.6 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PVD34765.1 - 2.5e-05 24.3 0.8 0.91 9.4 0.1 3.6 3 0 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 PVD34765.1 - 0.00014 21.5 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 PVD34765.1 - 0.00014 22.4 0.0 0.13 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PVD34765.1 - 0.00031 20.7 0.0 0.027 14.4 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 PVD34765.1 - 0.00048 19.4 0.0 0.021 14.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 PVD34765.1 - 0.00071 19.3 0.0 0.21 11.3 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PVD34765.1 - 0.00072 19.7 0.0 2 8.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 PVD34765.1 - 0.001 19.0 0.0 0.38 10.6 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PVD34765.1 - 0.0016 18.2 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PVD34765.1 - 0.0016 18.7 0.0 2.1 8.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.11 PVD34765.1 - 0.0031 17.4 0.1 0.99 9.3 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PVD34765.1 - 0.0031 16.9 0.5 0.93 8.8 0.1 2.8 3 1 0 3 3 2 1 KaiC Parvo_NS1 PF01057.17 PVD34765.1 - 0.0032 16.6 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 PVD34765.1 - 0.009 16.5 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 PVD34765.1 - 0.028 13.9 0.0 6.4 6.1 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein Vps4_C PF09336.10 PVD34765.1 - 0.032 14.2 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 PVD34765.1 - 0.11 11.9 0.1 3 7.3 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_ab PF00006.25 PVD34765.1 - 0.14 11.8 0.0 1 9.0 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_PrkA PF08298.11 PVD34765.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Nup35_RRM_2 PF14605.6 PVD34766.1 - 2.2e-12 46.8 0.1 2.8e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 PVD34766.1 - 3.1e-08 33.8 0.1 6.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 PVD34766.1 - 8.8e-07 28.7 2.7 0.011 15.5 0.3 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 PVD34766.1 - 0.0047 16.8 1.1 0.0088 15.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GED PF02212.18 PVD34766.1 - 0.021 14.9 0.7 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain 3HCDH_N PF02737.18 PVD34766.1 - 0.11 12.3 0.5 0.26 11.2 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf_CCCH_4 PF18345.1 PVD34766.1 - 0.18 11.9 0.6 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain CUB PF00431.20 PVD34767.1 - 2.5e-21 76.1 0.2 2.9e-15 56.5 0.1 2.6 2 0 0 2 2 2 2 CUB domain 7tm_2 PF00002.24 PVD34767.1 - 5.4e-15 55.4 11.9 1.2e-14 54.2 10.4 1.9 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) GPS PF01825.21 PVD34767.1 - 1.3e-10 41.7 2.6 1.3e-10 41.7 2.6 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 PVD34767.1 - 7.9e-07 28.7 0.0 8e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain HRM PF02793.22 PVD34767.1 - 6.6e-05 23.1 0.5 0.00019 21.7 0.5 1.8 1 0 0 1 1 1 1 Hormone receptor domain CMAS PF02353.20 PVD34768.1 - 1e-44 152.9 2.9 1.3e-44 152.5 2.9 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 PVD34768.1 - 6.5e-15 55.3 0.1 1.8e-14 53.9 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD34768.1 - 3.5e-12 46.9 0.0 9.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD34768.1 - 1.8e-11 44.5 0.0 3.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD34768.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD34768.1 - 6.8e-09 36.4 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD34768.1 - 1.2e-08 34.8 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 PVD34768.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 PVD34768.1 - 0.0048 16.2 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G FtsJ PF01728.19 PVD34768.1 - 0.0061 16.7 0.2 0.067 13.3 0.2 2.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 PVD34768.1 - 0.073 13.0 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 PVD34768.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 PVD34768.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Big_3_2 PF12245.8 PVD34769.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain fn3 PF00041.21 PVD34770.1 - 2.4e-12 47.0 14.6 0.09 13.1 0.6 10.3 10 0 0 10 10 10 6 Fibronectin type III domain Big_3_2 PF12245.8 PVD34770.1 - 0.0098 16.2 0.1 0.44 10.8 0.0 3.4 3 0 0 3 3 3 1 Bacterial Ig-like domain CheC PF04509.12 PVD34771.1 - 0.022 14.6 1.1 28 4.7 0.0 3.8 3 0 0 3 3 3 0 CheC-like family Big_3_2 PF12245.8 PVD34772.1 - 0.0065 16.7 0.1 0.31 11.3 0.1 3.2 2 0 0 2 2 2 1 Bacterial Ig-like domain Big_3_3 PF13750.6 PVD34772.1 - 0.017 14.8 0.5 1.3e+02 2.2 0.0 6.2 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 3) DUF3048_C PF17479.2 PVD34772.1 - 0.05 14.0 0.1 2.3 8.6 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain CheC PF04509.12 PVD34772.1 - 0.99 9.4 6.8 26 4.8 0.0 4.4 4 0 0 4 4 4 0 CheC-like family Homeodomain PF00046.29 PVD34773.1 - 6e-20 70.9 4.7 9.7e-20 70.2 4.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD34773.1 - 0.0067 16.3 1.6 0.015 15.2 1.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Terminase_5 PF06056.12 PVD34773.1 - 0.097 12.6 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Sushi PF00084.20 PVD34776.1 - 0.033 14.8 0.1 0.056 14.0 0.1 1.5 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) IgGFc_binding PF17517.2 PVD34777.1 - 9.1e-47 159.7 1.3 9.1e-47 159.7 1.3 2.9 2 1 1 3 3 3 2 IgGFc binding protein EGF PF00008.27 PVD34777.1 - 3.2e-18 65.7 46.6 8.7e-07 29.1 4.2 4.9 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 PVD34777.1 - 3e-13 49.8 37.7 1.6e-05 25.3 2.0 5.0 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_CA PF07645.15 PVD34777.1 - 0.0062 16.7 52.5 0.041 14.1 8.7 4.5 3 1 1 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 PVD34777.1 - 3.8 7.5 33.6 1.8 8.6 2.3 4.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD34777.1 - 4.4 7.6 55.5 0.048 13.9 5.6 5.6 4 1 1 5 5 5 0 EGF domain EGF_2 PF07974.13 PVD34777.1 - 6.9 7.1 54.9 0.23 11.9 10.5 4.5 4 0 0 4 4 4 0 EGF-like domain SSF PF00474.17 PVD34778.1 - 6.5e-39 133.9 2.0 1.3e-38 132.9 2.0 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family DUF2569 PF10754.9 PVD34778.1 - 0.0089 16.5 3.9 0.0089 16.5 3.9 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2569) DUF4231 PF14015.6 PVD34778.1 - 7.5 7.1 10.8 0.2 12.1 0.4 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) SSF PF00474.17 PVD34779.1 - 3.9e-37 128.1 1.6 2.8e-36 125.2 2.1 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family UQ_con PF00179.26 PVD34779.1 - 1.8e-07 30.9 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FANCF PF11107.8 PVD34780.1 - 1.9e-17 63.5 11.9 5.2e-14 52.2 11.9 2.0 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) V-set PF07686.17 PVD34781.1 - 4e-05 23.7 0.0 8.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD34781.1 - 0.00018 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD34781.1 - 0.013 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 PVD34782.1 - 0.0007 20.1 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD34782.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD34782.1 - 0.065 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain UCR_Fe-S_N PF10399.9 PVD34782.1 - 1.2 8.5 3.5 2.8 7.3 3.5 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ig_3 PF13927.6 PVD34783.1 - 0.091 13.4 0.1 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain PDZ PF00595.24 PVD34788.1 - 5.3e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD34788.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD34788.1 - 0.00062 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain MOR2-PAG1_N PF14222.6 PVD34789.1 - 7.8e-161 536.7 6.7 9.1e-160 533.2 4.5 2.3 2 0 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 PVD34789.1 - 5e-64 216.6 2.5 5e-64 216.6 2.5 3.7 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 PVD34789.1 - 2.9e-35 121.3 13.7 8.3e-11 40.3 0.1 6.3 6 1 1 7 7 7 5 Cell morphogenesis central region HEAT_2 PF13646.6 PVD34789.1 - 0.00067 20.0 0.1 0.009 16.4 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Folate_rec PF03024.14 PVD34790.1 - 3.3e-25 88.9 5.7 3.3e-25 88.9 5.7 1.3 1 1 0 1 1 1 1 Folate receptor family Folate_rec PF03024.14 PVD34791.1 - 3.9e-26 91.9 5.1 5e-26 91.6 5.1 1.3 1 0 0 1 1 1 1 Folate receptor family NDUF_C2 PF06374.11 PVD34792.1 - 1.1e-21 77.0 0.0 1.2e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF533 PF04391.12 PVD34792.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Ribosomal_S3Ae PF01015.18 PVD34793.1 - 2.7e-99 330.8 7.5 3.2e-99 330.5 7.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 PVD34793.1 - 0.0097 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region NLRC4_HD2 PF17776.1 PVD34793.1 - 0.028 15.0 0.1 0.043 14.4 0.1 1.2 1 0 0 1 1 1 0 NLRC4 helical domain HD2 DDE_Tnp_2 PF04693.12 PVD34794.1 - 0.09 12.0 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 RAI16-like PF10257.9 PVD34795.1 - 4.2e-83 279.2 8.3 7.9e-83 278.3 8.3 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein R3H PF01424.22 PVD34795.1 - 0.13 12.2 0.2 0.48 10.4 0.2 1.9 1 0 0 1 1 1 0 R3H domain SH3_9 PF14604.6 PVD34796.1 - 5.7e-43 144.5 3.1 1.3e-14 53.8 0.1 4.5 3 1 1 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 PVD34796.1 - 6.1e-42 141.0 1.9 7.5e-12 44.7 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 PVD34796.1 - 1.4e-29 101.5 4.2 3.5e-13 49.0 0.0 4.3 3 1 1 4 4 4 4 Variant SH3 domain zf-RING_2 PF13639.6 PVD34796.1 - 2.1e-08 34.3 11.6 6.3e-08 32.8 10.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD34796.1 - 2.3e-08 33.7 10.2 5.6e-08 32.5 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD34796.1 - 2.6e-08 33.7 7.7 5.9e-08 32.6 7.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD34796.1 - 3.7e-08 33.1 10.7 7.5e-08 32.1 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD34796.1 - 4.1e-07 29.8 8.6 7.5e-07 28.9 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD34796.1 - 2e-06 27.7 10.1 3.7e-06 26.8 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 PVD34796.1 - 5e-05 23.0 6.9 9.3e-05 22.1 6.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PVD34796.1 - 0.00019 21.2 8.6 0.00042 20.1 8.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD34796.1 - 0.00066 19.8 9.2 0.0013 18.8 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 PVD34796.1 - 0.0036 17.0 8.7 0.0086 15.8 2.8 2.6 1 1 1 2 2 2 1 RING-like zinc finger HSP70 PF00012.20 PVD34796.1 - 0.09 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-RING_10 PF16685.5 PVD34796.1 - 0.093 12.9 6.1 0.19 11.9 6.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Herpes_LMP1 PF05297.11 PVD34796.1 - 0.097 11.9 0.0 0.097 11.9 0.0 2.3 3 0 0 3 3 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1272 PF06906.11 PVD34796.1 - 0.25 11.5 5.0 0.65 10.1 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 PVD34796.1 - 0.27 11.1 3.4 0.61 10.0 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 PVD34796.1 - 0.31 11.1 5.8 0.73 9.9 5.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon Dicty_REP PF05086.12 PVD34796.1 - 1.3 6.9 2.6 2.4 6.0 2.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zinc-ribbons_6 PF07191.12 PVD34796.1 - 2.7 8.0 7.2 5.3 7.1 7.2 1.5 1 0 0 1 1 1 0 zinc-ribbons Trm112p PF03966.16 PVD34796.1 - 3.5 8.3 5.3 8.8 7.0 5.3 1.7 1 0 0 1 1 1 0 Trm112p-like protein DUF668 PF05003.12 PVD34797.1 - 0.026 15.0 0.3 0.095 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Dimer_Tnp_hAT PF05699.14 PVD34797.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region YccF PF03733.13 PVD34798.1 - 3.1e-18 66.2 13.2 3.1e-18 66.2 13.2 5.2 7 0 0 7 7 7 2 Inner membrane component domain Na_Ca_ex PF01699.24 PVD34798.1 - 4.1e-12 46.3 13.2 4.1e-12 46.3 13.2 4.1 4 1 1 5 5 5 2 Sodium/calcium exchanger protein CTXphi_pIII-N1 PF16710.5 PVD34798.1 - 1.4 9.1 4.5 6.3 7.0 0.2 2.9 3 0 0 3 3 3 0 N-terminal N1 domain of Vibrio phage CTXphi pIII PQQ_3 PF13570.6 PVD34799.1 - 1e-33 114.9 1.6 3.9e-05 24.0 0.0 7.7 7 0 0 7 7 7 7 PQQ-like domain PQQ PF01011.21 PVD34799.1 - 1.7e-28 97.1 5.4 4.2e-05 23.3 0.1 8.2 8 0 0 8 8 8 6 PQQ enzyme repeat AMP-binding PF00501.28 PVD34799.1 - 1.4e-27 96.4 0.4 2.3e-27 95.6 0.4 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.6 PVD34799.1 - 1.6e-24 86.8 0.0 9.9e-14 51.5 0.0 3.6 2 1 0 3 3 3 3 PQQ-like domain PP-binding PF00550.25 PVD34799.1 - 1.3e-05 25.4 0.0 3.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 PVD34799.1 - 0.0088 17.0 0.2 0.021 15.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 PVD34799.1 - 0.017 16.0 1.7 1.5 9.8 0.1 4.7 3 0 0 3 3 3 0 WD domain, G-beta repeat RmlD_sub_bind PF04321.17 PVD34800.1 - 1.2e-53 182.1 0.0 4.6e-39 134.2 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 PVD34800.1 - 3.4e-22 79.1 0.0 4.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD34800.1 - 3.8e-14 52.8 0.1 7.3e-14 51.9 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PVD34800.1 - 3.5e-11 42.8 1.9 1.2e-09 37.7 0.1 3.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PVD34800.1 - 1.7e-09 37.3 0.0 2.4e-07 30.2 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 PVD34800.1 - 1.7e-05 24.0 0.8 0.00015 20.9 0.3 2.4 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 PVD34800.1 - 0.038 14.1 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 PVD34800.1 - 0.78 9.6 4.3 6.3 6.7 0.1 2.8 2 1 1 3 3 3 0 KR domain ANAPC10 PF03256.16 PVD34802.1 - 1.3e-44 152.1 0.0 1.5e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 PVD34802.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 PITH domain WD40 PF00400.32 PVD34803.1 - 1.2e-42 143.0 17.8 9e-08 32.7 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 PVD34803.1 - 0.00016 20.5 2.6 0.14 10.8 1.3 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PVD34803.1 - 0.00038 19.3 0.0 4 6.1 0.0 4.3 1 1 1 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.6 PVD34803.1 - 0.1 12.6 0.0 7.2 6.7 0.0 3.3 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 PVD34803.1 - 0.11 12.2 1.8 8.9 6.0 0.1 3.3 1 1 3 4 4 4 0 TUP1-like enhancer of split Pkinase PF00069.25 PVD34804.1 - 1.5e-46 159.0 8.5 9.9e-27 93.9 0.0 3.2 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34804.1 - 2.4e-30 105.7 0.0 6e-16 58.5 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Homeodomain PF00046.29 PVD34805.1 - 7.4e-23 80.2 5.4 1.1e-22 79.6 5.4 1.3 1 0 0 1 1 1 1 Homeodomain NAM-associated PF14303.6 PVD34805.1 - 0.037 14.7 7.9 0.053 14.2 7.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 PVD34805.1 - 0.07 12.7 6.5 0.086 12.4 6.5 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_Ag35 PF03286.14 PVD34805.1 - 2.3 8.0 8.9 1.5 8.6 7.6 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF4663 PF15668.5 PVD34806.1 - 0.084 11.9 2.2 0.14 11.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Mito_fiss_reg PF05308.11 PVD34806.1 - 1.3 9.1 7.1 2.6 8.1 7.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Homeodomain PF00046.29 PVD34808.1 - 4.4e-21 74.5 4.6 7.9e-21 73.7 4.6 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 PVD34808.1 - 0.074 12.9 1.3 0.17 11.7 0.2 2.2 1 1 1 2 2 2 0 Homeodomain-like domain Homeobox_KN PF05920.11 PVD34808.1 - 0.084 12.8 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain Terminase_5 PF06056.12 PVD34808.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Glyco_transf_10 PF00852.19 PVD34809.1 - 3e-45 154.1 1.5 4.1e-45 153.6 1.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD34809.1 - 1.2e-06 28.9 0.1 3.3e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 Fucosyltransferase, N-terminal SSF PF00474.17 PVD34810.1 - 1.3e-10 40.7 9.7 1.3e-10 40.7 9.7 2.7 3 1 0 3 3 3 2 Sodium:solute symporter family Nucleos_tra2_N PF01773.20 PVD34814.1 - 2.9e-17 63.0 0.9 2.9e-17 63.0 0.9 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 PVD34814.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 3.2 3 1 1 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_C PF07662.13 PVD34815.1 - 5.4e-15 55.8 0.2 8e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus DBD_Tnp_Mut PF03108.15 PVD34815.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 MuDR family transposase Ank_2 PF12796.7 PVD34816.1 - 2.3e-25 89.0 0.5 8.1e-11 42.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD34816.1 - 1.6e-19 67.9 0.4 0.00085 19.6 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 PVD34816.1 - 2.4e-18 66.3 0.4 2.1e-07 31.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD34816.1 - 1.1e-15 57.2 0.8 3.8e-05 23.9 0.6 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PVD34816.1 - 1.4e-13 50.8 0.2 9.2e-08 32.2 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) ABC_tran PF00005.27 PVD34817.1 - 5.6e-36 124.1 0.0 1.6e-16 61.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 PVD34817.1 - 2.3e-13 49.7 6.1 2.3e-13 49.7 6.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 PVD34817.1 - 4.4e-12 45.9 3.7 0.0003 20.3 0.2 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PVD34817.1 - 2.4e-10 40.7 6.8 0.19 11.5 1.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 PVD34817.1 - 2.8e-08 33.2 2.9 2.8e-08 33.2 2.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 PVD34817.1 - 2.2e-05 24.4 0.0 0.1 12.5 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 PVD34817.1 - 2.4e-05 24.8 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 PVD34817.1 - 2.9e-05 24.0 1.9 0.18 11.5 0.2 3.3 3 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 PVD34817.1 - 5e-05 23.7 0.0 0.077 13.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 PVD34817.1 - 5.3e-05 23.1 2.5 5.3e-05 23.1 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 PVD34817.1 - 7.5e-05 23.0 0.0 0.019 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PVD34817.1 - 0.00061 19.5 0.4 1.3 8.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 PVD34817.1 - 0.00087 19.2 0.5 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_2 PF12797.7 PVD34817.1 - 0.0013 18.7 0.7 0.0013 18.7 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.22 PVD34817.1 - 0.0016 18.8 1.1 0.55 10.7 0.0 3.3 3 0 0 3 3 3 1 RNA helicase TsaE PF02367.17 PVD34817.1 - 0.0016 18.4 0.1 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 PVD34817.1 - 0.0016 18.1 2.1 0.14 11.7 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 PVD34817.1 - 0.0018 18.5 0.1 0.41 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PVD34817.1 - 0.0024 17.6 1.7 0.18 11.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 PVD34817.1 - 0.0024 17.9 11.5 0.0071 16.4 11.6 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 PVD34817.1 - 0.0026 17.7 0.0 0.77 9.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_7 PF12838.7 PVD34817.1 - 0.0034 17.9 1.1 0.0034 17.9 1.1 2.4 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 PVD34817.1 - 0.0049 17.0 9.8 0.011 15.9 9.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PVD34817.1 - 0.0059 16.7 1.3 0.0059 16.7 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain VirE PF05272.11 PVD34817.1 - 0.0099 15.6 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 PVD34817.1 - 0.011 16.7 0.3 0.011 16.7 0.3 2.8 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.6 PVD34817.1 - 0.013 15.7 0.8 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PVD34817.1 - 0.016 14.7 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 PVD34817.1 - 0.025 14.7 0.1 9.1 6.4 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 PVD34817.1 - 0.026 15.1 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD34817.1 - 0.035 13.3 0.1 3.4 6.8 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 PVD34817.1 - 0.053 13.2 1.5 1.2 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 PVD34817.1 - 0.084 13.3 0.2 0.084 13.3 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 PVD34817.1 - 0.094 12.4 0.1 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Thymidylate kinase Septin PF00735.18 PVD34817.1 - 0.14 11.5 0.0 3.3 6.9 0.0 2.5 3 0 0 3 3 2 0 Septin AAA_14 PF13173.6 PVD34817.1 - 0.17 11.9 3.2 12 6.0 0.0 3.5 2 2 1 3 3 3 0 AAA domain Roc PF08477.13 PVD34817.1 - 0.19 12.0 0.6 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 PVD34817.1 - 0.34 11.4 9.2 0.17 12.4 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PVD34817.1 - 0.5 10.4 2.0 3.6 7.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_4 PF12800.7 PVD34817.1 - 1.1 9.9 14.2 1 10.0 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 PVD34817.1 - 4.4 7.2 5.9 6.7 6.6 0.1 3.4 4 0 0 4 4 4 0 NTPase Fer4_17 PF13534.6 PVD34817.1 - 7 7.3 11.3 0.094 13.3 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Nup54 PF13874.6 PVD34818.1 - 4.9e-45 153.1 3.4 4.9e-45 153.1 3.4 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 PVD34818.1 - 6.8e-15 54.7 6.8 6.8e-15 54.7 6.8 2.4 3 0 0 3 3 3 1 Nup54 C-terminal interacting domain Nucleoporin_FG PF13634.6 PVD34818.1 - 0.0094 16.8 38.0 0.0094 16.8 38.0 2.4 1 1 1 2 2 2 1 Nucleoporin FG repeat region Med3 PF11593.8 PVD34818.1 - 0.61 9.2 6.6 1.5 8.0 6.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nucleoporin_FG2 PF15967.5 PVD34818.1 - 2.1 6.8 48.7 3.4 6.1 48.7 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region p450 PF00067.22 PVD34819.1 - 2.9e-75 253.8 0.7 2.1e-74 251.0 0.1 2.3 1 1 1 2 2 2 1 Cytochrome P450 p450 PF00067.22 PVD34820.1 - 1.2e-66 225.4 1.9 4.6e-58 197.1 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 RII_binding_1 PF10522.9 PVD34820.1 - 0.12 12.7 0.3 0.28 11.5 0.3 1.7 1 0 0 1 1 1 0 RII binding domain p450 PF00067.22 PVD34821.1 - 6.8e-60 203.1 0.2 1.6e-43 149.1 0.1 2.0 1 1 0 2 2 2 2 Cytochrome P450 MR_MLE_C PF13378.6 PVD34822.1 - 5.6e-27 94.7 0.0 7.9e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like VioE PF18234.1 PVD34823.1 - 0.23 11.6 1.3 0.27 11.4 0.3 1.5 1 1 1 2 2 2 0 Violacein biosynthetic enzyme VioE TPR_12 PF13424.6 PVD34824.1 - 1.6e-23 82.8 15.5 9e-08 32.3 0.1 5.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 PVD34824.1 - 4.3e-21 73.3 23.1 0.015 15.4 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD34824.1 - 2.6e-18 65.0 30.0 0.0022 17.8 0.0 8.2 8 1 1 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 PVD34824.1 - 1.5e-11 43.5 28.5 0.072 13.3 0.3 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 PVD34824.1 - 3.9e-11 42.2 12.2 0.024 14.6 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD34824.1 - 3.5e-09 36.5 0.9 4.1e-06 26.4 0.1 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 PVD34824.1 - 1.8e-08 34.0 8.3 0.097 12.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD34824.1 - 1.8e-07 31.4 9.1 0.81 10.7 0.1 7.6 5 2 3 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD34824.1 - 2.1e-07 31.0 8.7 0.038 14.2 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD34824.1 - 9.4e-07 29.4 6.6 0.01 16.5 0.1 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD34824.1 - 1.9e-06 27.5 10.1 1 9.1 0.1 6.7 7 0 0 7 7 7 2 TPR repeat TPR_19 PF14559.6 PVD34824.1 - 2.6e-06 27.8 13.1 0.0028 18.1 0.2 5.4 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD34824.1 - 3.2e-06 27.1 9.9 3.7 8.1 0.0 6.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD34824.1 - 0.00014 21.9 4.5 1.8 8.8 0.0 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 PVD34824.1 - 0.00017 21.5 0.8 0.3 11.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 PVD34824.1 - 0.00043 20.3 5.4 0.17 12.0 0.1 3.9 5 0 0 5 5 4 2 Rapsyn N-terminal myristoylation and linker region RPN7 PF10602.9 PVD34824.1 - 0.00054 19.7 9.2 0.06 13.1 0.8 4.5 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 PVD34824.1 - 0.00084 19.7 0.0 11 7.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 PVD34824.1 - 0.03 14.4 16.8 0.064 13.3 0.5 5.6 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 PVD34824.1 - 0.043 14.5 17.5 4.8 8.0 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD34824.1 - 1.5 8.9 10.0 14 5.7 0.1 5.1 3 2 2 5 5 5 0 Putative TPR-like repeat MIP PF00230.20 PVD34825.1 - 7.2e-52 176.4 10.0 1e-51 175.8 10.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 PVD34826.1 - 1.5e-59 201.5 0.0 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34826.1 - 1.9e-42 145.4 0.0 2.4e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD34826.1 - 1.3e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 PVD34826.1 - 5.1e-05 22.5 0.2 0.00036 19.7 0.1 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 PVD34826.1 - 0.007 15.2 0.1 0.036 12.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD34826.1 - 0.013 14.4 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Prominin PF05478.11 PVD34827.1 - 3.2e-121 405.8 19.4 3.9e-92 309.6 11.3 2.0 1 1 1 2 2 2 2 Prominin Shisa PF13908.6 PVD34827.1 - 0.017 15.4 1.3 0.017 15.4 1.3 3.5 2 2 2 4 4 4 0 Wnt and FGF inhibitory regulator DUF5422 PF17459.2 PVD34827.1 - 0.032 14.4 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5422) DUF5631 PF18645.1 PVD34827.1 - 0.092 13.1 1.8 0.95 9.9 0.0 3.4 3 1 0 4 4 4 0 Family of unknown function (DUF5631) DUF1664 PF07889.12 PVD34827.1 - 0.26 11.3 10.5 3 7.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Claudin_2 PF13903.6 PVD34827.1 - 0.28 10.9 5.0 1.1 8.9 0.1 3.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF948 PF06103.11 PVD34827.1 - 1.4 9.3 0.0 1.4 9.3 0.0 5.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 PVD34827.1 - 4 7.6 25.4 0.3 11.3 4.7 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DNA_ligase_A_M PF01068.21 PVD34828.1 - 8.8e-36 123.5 0.1 5.1e-17 62.2 0.1 2.8 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 PVD34828.1 - 1e-24 87.0 0.0 4.7e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 PVD34828.1 - 1.4e-24 87.4 5.2 1.1e-23 84.5 0.1 2.7 2 0 0 2 2 2 1 DNA ligase N terminus RPN5_C PF18098.1 PVD34828.1 - 1.9e-15 56.6 1.2 4.1e-15 55.6 1.2 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 PVD34828.1 - 0.0045 17.5 0.7 0.31 11.6 0.0 3.5 2 1 0 2 2 2 1 PCI domain DNA_ligase_OB_2 PF14743.6 PVD34828.1 - 0.064 13.3 0.4 7.7 6.6 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain C1q PF00386.21 PVD34829.1 - 1.4e-24 86.8 0.1 1.7e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 PVD34829.1 - 4.8e-17 61.5 55.9 1.6e-09 37.4 22.4 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF4551 PF15087.6 PVD34830.1 - 9.8 4.9 8.2 11 4.6 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Solute_trans_a PF03619.16 PVD34831.1 - 2.8e-92 309.0 16.5 3.4e-92 308.7 16.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2975 PF11188.8 PVD34831.1 - 0.33 10.8 7.9 0.046 13.6 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) UNC-93 PF05978.16 PVD34832.1 - 2.1e-43 147.8 11.9 2.1e-43 147.8 11.9 2.9 3 1 0 3 3 3 2 Ion channel regulatory protein UNC-93 RRM_1 PF00076.22 PVD34833.1 - 3.2e-22 78.1 0.0 4.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PVD34833.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4693 PF15764.5 PVD34834.1 - 9.3e-13 48.4 0.1 5.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4693) DUF550 PF04447.12 PVD34834.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) RRM_1 PF00076.22 PVD34835.1 - 2.8e-13 49.5 0.0 5.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 PVD34835.1 - 2.7e-09 36.6 2.8 6.5e-09 35.3 2.8 1.7 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.6 PVD34835.1 - 5.2e-05 22.8 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAR_sialic_bdg PF10564.9 PVD34835.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Tektin PF03148.14 PVD34836.1 - 1.8e-146 487.8 39.0 2.1e-146 487.6 39.0 1.0 1 0 0 1 1 1 1 Tektin family CdvA PF18822.1 PVD34836.1 - 0.0083 15.9 2.3 0.0083 15.9 2.3 3.8 3 1 0 4 4 4 1 CdvA-like coiled-coil domain MitMem_reg PF13012.6 PVD34836.1 - 0.076 13.4 4.6 0.34 11.3 0.1 3.1 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.12 PVD34836.1 - 0.11 12.5 13.0 0.078 13.0 1.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 PVD34836.1 - 0.62 10.7 9.0 3.1 8.5 0.5 3.5 3 0 0 3 3 3 0 SlyX COG2 PF06148.11 PVD34836.1 - 7.4 6.7 15.4 0.84 9.7 0.7 4.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Linker_histone PF00538.19 PVD34837.1 - 5e-13 49.2 0.0 5e-13 49.2 0.0 3.4 2 2 1 3 3 3 1 linker histone H1 and H5 family Forkhead PF00250.18 PVD34837.1 - 2.3e-05 24.6 0.2 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 Forkhead domain BLOC1_2 PF10046.9 PVD34838.1 - 0.00076 19.7 4.4 0.0031 17.8 4.4 2.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TolA_bind_tri PF16331.5 PVD34838.1 - 0.002 18.2 14.0 0.002 18.2 14.0 2.6 3 0 0 3 3 3 1 TolA binding protein trimerisation DUF4187 PF13821.6 PVD34838.1 - 0.1 12.4 3.6 0.69 9.7 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Bcr-Abl_Oligo PF09036.10 PVD34838.1 - 0.39 10.8 3.6 0.47 10.5 1.2 2.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CP12 PF02672.15 PVD34838.1 - 0.89 10.4 5.7 2 9.2 3.5 2.6 2 0 0 2 2 2 0 CP12 domain TMPIT PF07851.13 PVD34838.1 - 1.1 8.4 4.4 2.8 7.1 4.4 1.6 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 PVD34838.1 - 5.4 6.8 11.7 0.23 11.3 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 PVD34838.1 - 8.9 5.6 10.6 20 4.4 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4 PF00105.18 PVD34839.1 - 1.2e-27 96.2 11.6 2.7e-27 95.0 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD34839.1 - 0.00093 18.8 0.0 0.00093 18.8 0.0 2.6 3 0 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor PDDEXK_6 PF04720.12 PVD34839.1 - 6.3 6.7 8.0 2.8 7.8 4.9 1.9 2 0 0 2 2 2 0 PDDEXK-like family of unknown function M_domain PF12938.7 PVD34841.1 - 1.4e-11 44.7 47.0 1.4e-11 44.7 47.0 5.4 4 1 1 5 5 5 1 M domain of GW182 UBA PF00627.31 PVD34841.1 - 2.5e-06 27.3 0.2 5e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 PVD34841.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PVD34841.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif MMM1 PF10296.9 PVD34842.1 - 8.9e-10 38.1 0.3 1.9e-09 37.0 0.0 1.7 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Ribonuc_2-5A PF06479.12 PVD34843.1 - 2.3e-44 150.6 1.3 3.9e-44 149.9 1.3 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 PVD34843.1 - 2.1e-32 112.6 0.0 4.9e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD34843.1 - 3e-18 66.1 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 PVD34843.1 - 0.00018 21.1 0.3 0.3 10.6 0.0 2.7 2 1 1 3 3 3 2 PQQ-like domain Pkinase_fungal PF17667.1 PVD34843.1 - 0.0026 16.6 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD34843.1 - 0.0096 15.9 0.0 0.28 11.1 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family TssO PF17561.2 PVD34843.1 - 0.014 15.5 0.7 0.031 14.4 0.7 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO PQQ PF01011.21 PVD34843.1 - 0.098 12.6 0.0 11 6.2 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat Ank_2 PF12796.7 PVD34844.1 - 9.7e-18 64.5 0.0 3.3e-08 34.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD34844.1 - 2.8e-12 46.6 0.4 8.1e-08 32.4 0.0 4.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34844.1 - 1.6e-11 43.3 3.3 0.0093 16.4 0.0 5.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 PVD34844.1 - 1.1e-09 38.6 0.7 9.4e-05 22.9 0.1 4.4 3 2 2 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD34844.1 - 2.5e-09 37.2 1.7 0.0036 17.7 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat SOCS_box PF07525.16 PVD34844.1 - 2e-08 34.5 3.3 4.2e-08 33.4 3.3 1.5 1 0 0 1 1 1 1 SOCS box Ras PF00071.22 PVD34845.1 - 4.7e-35 120.6 0.0 5.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD34845.1 - 5e-17 62.2 0.0 6.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 PVD34845.1 - 0.00053 19.9 0.7 0.21 11.4 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Arf PF00025.21 PVD34845.1 - 0.0047 16.4 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 PVD34845.1 - 0.051 13.9 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PVD34845.1 - 0.06 13.2 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 PVD34845.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 PVD34845.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 PVD34845.1 - 0.089 13.3 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 PVD34845.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain CPSase_L_D2 PF02786.17 PVD34846.1 - 4.4e-114 379.2 0.2 7.8e-81 270.6 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 PVD34846.1 - 1e-48 164.4 0.0 4.1e-48 162.4 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 PVD34846.1 - 3.9e-44 150.7 0.0 1.1e-43 149.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 PVD34846.1 - 4.9e-36 123.8 0.1 2.2e-35 121.7 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 PVD34846.1 - 1.5e-17 63.5 0.2 1.6e-16 60.2 0.0 2.8 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.22 PVD34846.1 - 1.3e-16 60.6 0.1 1e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PVD34846.1 - 1.1e-13 51.2 0.2 8.9e-07 28.6 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 PVD34846.1 - 9.6e-12 44.8 0.0 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 PVD34846.1 - 1.8e-06 27.9 0.1 0.00012 21.9 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 PVD34846.1 - 2.7e-05 24.3 0.1 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 PVD34846.1 - 4.4e-05 23.1 0.2 0.33 10.4 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 PVD34846.1 - 0.066 13.0 0.1 0.94 9.3 0.0 2.6 3 0 0 3 3 3 0 DJ-1/PfpI family TrkA_N PF02254.18 PVD34846.1 - 0.14 12.4 0.1 5.5 7.3 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Ependymin PF00811.18 PVD34847.1 - 8e-15 55.2 0.0 1.5e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 Ependymin Ependymin PF00811.18 PVD34848.1 - 1.2e-15 57.9 0.1 2.1e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Ependymin DUF3432 PF11914.8 PVD34848.1 - 0.02 15.1 1.0 0.058 13.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Ependymin PF00811.18 PVD34849.1 - 2.8e-07 30.9 0.1 4.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Ependymin CAP PF00188.26 PVD34852.1 - 8.1e-24 84.9 9.3 2.1e-12 48.0 0.8 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family FGAR-AT_linker PF18072.1 PVD34852.1 - 0.061 13.9 0.4 1.5 9.4 0.1 2.4 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain CAP PF00188.26 PVD34853.1 - 2.3e-07 31.7 0.3 3.2e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family OB_NTP_bind PF07717.16 PVD34856.1 - 9.4e-14 51.6 0.1 1.5e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold p450 PF00067.22 PVD34858.1 - 1.1e-91 308.0 0.1 5.3e-61 206.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 TerB_C PF15615.6 PVD34858.1 - 0.041 14.2 1.6 0.071 13.4 1.6 1.2 1 0 0 1 1 1 0 TerB-C domain VAPB_antitox PF02697.14 PVD34858.1 - 0.041 14.6 0.4 0.27 12.0 0.4 2.1 2 0 0 2 2 2 0 Putative antitoxin p450 PF00067.22 PVD34859.1 - 1.9e-95 320.3 0.1 7.1e-95 318.4 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 Dpy19 PF10034.9 PVD34860.1 - 0.00045 18.6 0.1 0.00075 17.8 0.1 1.3 1 0 0 1 1 1 1 Q-cell neuroblast polarisation PAN_1 PF00024.26 PVD34860.1 - 0.0028 17.6 1.8 0.0032 17.4 0.1 2.1 2 0 0 2 2 2 1 PAN domain Vac17 PF17321.2 PVD34860.1 - 1.2 8.5 11.4 1.9 7.9 11.4 1.2 1 0 0 1 1 1 0 Vacuole-related protein 17 SH3_1 PF00018.28 PVD34861.1 - 7.9e-24 83.0 2.4 1.8e-11 43.5 0.3 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 PVD34861.1 - 8.1e-22 76.8 1.5 9.1e-08 31.9 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 PVD34861.1 - 7.4e-15 54.4 0.2 2.4e-06 27.1 0.1 4.1 4 0 0 4 4 4 2 Variant SH3 domain TMEM154 PF15102.6 PVD34861.1 - 0.0037 17.2 0.0 0.0037 17.2 0.0 4.5 6 0 0 6 6 6 1 TMEM154 protein family FixQ PF05545.11 PVD34861.1 - 0.014 15.3 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Cadherin_C_2 PF16492.5 PVD34861.1 - 0.15 12.8 1.2 0.99 10.2 0.0 3.0 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal SIT PF15330.6 PVD34861.1 - 0.19 12.1 1.2 0.51 10.8 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4519 PF15012.6 PVD34861.1 - 0.48 10.6 2.4 1.4 9.2 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Stevor PF17410.2 PVD34861.1 - 0.62 9.5 0.0 0.62 9.5 0.0 2.6 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 PVD34861.1 - 4.9 7.5 0.0 4.9 7.5 0.0 3.4 4 0 0 4 4 4 0 Orf78 (ac78) DALR_1 PF05746.15 PVD34862.1 - 5.3e-30 104.0 0.1 5.3e-30 104.0 0.1 1.5 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 PVD34862.1 - 4.7e-27 94.9 0.3 6.7e-27 94.4 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1d PF00750.19 PVD34867.1 - 3.4e-98 328.8 0.1 6.5e-98 327.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 PVD34867.1 - 2.1e-12 47.5 0.0 5.5e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 PVD34867.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ABC_tran_CTD PF16326.5 PVD34867.1 - 0.0052 17.0 0.1 0.016 15.4 0.1 1.8 1 0 0 1 1 1 1 ABC transporter C-terminal domain CCDC24 PF15669.5 PVD34867.1 - 0.04 13.8 1.8 0.079 12.8 1.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NOG1_N PF17835.1 PVD34867.1 - 0.13 12.2 0.3 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 NOG1 N-terminal helical domain MscS_porin PF12795.7 PVD34867.1 - 0.13 11.8 0.8 0.25 10.9 0.8 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Phlebovirus_NSM PF07246.11 PVD34867.1 - 0.78 9.1 4.0 0.31 10.4 0.2 2.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.15 PVD34867.1 - 0.8 9.5 4.3 8.6 6.2 1.0 2.9 2 1 1 3 3 3 0 Septum formation initiator AvrM-A PF18241.1 PVD34867.1 - 4 7.8 6.4 1.8 8.9 0.4 2.8 2 1 1 3 3 3 0 Flax-rust effector AvrM-A RRM_1 PF00076.22 PVD34868.1 - 0.0043 16.9 0.1 6 6.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1_like PF12832.7 PVD34869.1 - 3.1e-51 174.5 0.0 3.3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 PVD34869.1 - 0.00012 21.0 7.1 0.00023 20.1 7.1 1.4 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 PVD34869.1 - 0.0023 16.5 14.2 0.0043 15.7 14.2 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein UBN_AB PF14075.6 PVD34870.1 - 1e-68 231.2 4.5 1e-68 231.2 4.5 2.6 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 PVD34870.1 - 3.4e-18 65.4 0.9 3.4e-18 65.4 0.9 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Glycos_transf_2 PF00535.26 PVD34871.1 - 2.8e-25 89.1 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PVD34871.1 - 5.6e-08 33.0 0.0 7.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD34871.1 - 2.7e-07 30.4 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PVD34871.1 - 0.021 15.3 0.0 0.048 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 PAPS_reduct PF01507.19 PVD34871.1 - 0.026 14.6 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Sec23_BS PF08033.12 PVD34871.1 - 0.13 13.0 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain PH PF00169.29 PVD34872.1 - 6.7e-23 81.2 5.5 7.2e-10 39.3 0.2 4.3 3 1 0 3 3 3 3 PH domain BTK PF00779.19 PVD34872.1 - 1.1e-16 60.3 15.3 5.8e-06 26.0 0.1 3.5 3 0 0 3 3 3 3 BTK motif THAP PF05485.12 PVD34872.1 - 0.024 15.6 0.9 2.7 9.0 0.1 3.2 3 1 0 3 3 3 0 THAP domain Roc PF08477.13 PVD34872.1 - 0.16 12.2 1.4 54 4.0 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PH_16 PF17838.1 PVD34872.1 - 0.55 10.1 3.1 1.9 8.4 0.1 2.9 3 1 0 3 3 3 0 PH domain DUF2650 PF10853.8 PVD34872.1 - 4.8 7.0 14.8 14 5.5 0.2 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2650) HSP90 PF00183.18 PVD34873.1 - 8.7e-170 566.0 38.4 7e-152 506.9 10.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 PVD34873.1 - 3.2e-17 63.1 0.1 6.4e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PVD34873.1 - 5.4e-11 42.5 0.1 1.4e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 PVD34873.1 - 0.083 12.9 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Tumour suppressor protein UDPGT PF00201.18 PVD34873.1 - 0.11 11.3 0.3 0.19 10.5 0.3 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ank_2 PF12796.7 PVD34874.1 - 1.1e-113 372.0 23.3 8.4e-18 64.7 0.0 10.2 1 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34874.1 - 5e-90 294.8 29.1 3e-10 40.4 0.0 14.8 3 2 13 16 16 16 15 Ankyrin repeats (many copies) Ank PF00023.30 PVD34874.1 - 4.6e-77 251.4 27.2 2.9e-08 33.8 0.1 17.9 19 0 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.6 PVD34874.1 - 1.7e-73 241.7 32.1 2.3e-12 46.9 0.5 12.8 4 3 10 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34874.1 - 6.8e-68 216.5 1.8 8.5e-05 22.7 0.0 17.3 18 0 0 18 18 18 12 Ankyrin repeat SPX PF03105.19 PVD34874.1 - 0.46 10.4 5.7 0.74 9.7 5.7 1.4 1 0 0 1 1 1 0 SPX domain AAA_16 PF13191.6 PVD34875.1 - 2.1e-10 41.3 0.0 3.1e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PVD34875.1 - 7.6e-09 35.7 0.4 2.9e-08 33.8 0.4 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 PVD34875.1 - 0.01 16.1 0.1 0.09 13.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD34875.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 PVD34875.1 - 0.043 14.2 0.4 0.12 12.9 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PVD34875.1 - 0.065 12.8 0.4 0.2 11.2 0.3 1.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PVD34875.1 - 0.086 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PVD34875.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PVD34876.1 - 5.3e-19 68.7 0.0 8.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD34876.1 - 4.7e-18 65.6 0.0 1.5e-13 51.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PVD34876.1 - 9e-07 29.5 0.7 9e-07 29.5 0.7 2.8 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 PVD34876.1 - 9.7e-07 28.9 0.0 4.1e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIS_M PF07500.14 PVD34876.1 - 0.24 11.9 3.8 0.12 12.9 0.7 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain SRI PF08236.11 PVD34876.1 - 0.47 10.7 6.8 0.064 13.4 0.6 3.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Glyco_transf_11 PF01531.16 PVD34877.1 - 8.8e-37 126.9 0.0 1.1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Sigma_reg_N PF13800.6 PVD34877.1 - 0.13 12.6 0.1 0.86 9.9 0.1 2.2 1 1 0 1 1 1 0 Sigma factor regulator N-terminal Melibiase_2 PF16499.5 PVD34878.1 - 2.4e-257 850.5 15.8 6.6e-147 488.2 4.0 3.0 2 1 1 3 3 3 3 Alpha galactosidase A Melibiase_2_C PF17450.2 PVD34878.1 - 1.1e-14 54.4 0.0 2.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 PVD34878.1 - 3.9e-08 32.6 0.0 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 2 Melibiase 2Fe-2S_thioredx PF01257.19 PVD34878.1 - 6.2e-05 22.9 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like [2Fe-2S] ferredoxin Melibiase_C PF17801.1 PVD34878.1 - 0.0018 18.3 0.0 0.006 16.6 0.0 2.0 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Toprim_3 PF13362.6 PVD34878.1 - 0.045 14.1 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Toprim domain PDEase_I PF00233.19 PVD34879.1 - 5.4e-73 245.6 3.4 5.4e-73 245.6 3.4 2.4 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PVD34879.1 - 7.2e-24 84.9 0.1 2.7e-15 57.2 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PVD34879.1 - 1.2e-19 70.9 0.0 1.9e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 PVD34879.1 - 6.2e-09 36.3 0.0 4.4e-06 27.1 0.0 2.9 2 0 0 2 2 2 2 GAF domain Nup96 PF12110.8 PVD34880.1 - 2.9e-89 299.1 3.3 2.9e-89 299.1 3.3 1.6 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 PVD34880.1 - 5.6e-46 156.3 0.0 9.5e-46 155.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Vps5 PF09325.10 PVD34881.1 - 3.5e-15 56.2 7.5 1e-11 44.9 3.4 2.1 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 PVD34881.1 - 3.9e-11 42.9 0.0 1.7e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 PVD34881.1 - 0.002 17.9 4.5 0.0039 16.9 4.5 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Phasin PF05597.11 PVD34881.1 - 0.23 11.5 3.6 0.24 11.4 0.4 2.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4570 PF15134.6 PVD34881.1 - 1 9.4 4.7 2.2 8.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) V-ATPase_G PF03179.15 PVD34881.1 - 2.6 8.6 6.5 1.4 9.4 1.2 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit zf-TAZ PF02135.16 PVD34882.1 - 3.2e-10 40.3 24.3 3.2e-10 40.3 24.3 3.3 2 2 0 2 2 2 1 TAZ zinc finger ComS PF17584.2 PVD34882.1 - 0.46 10.0 3.4 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Bacillus competence protein S Ribosomal_L31e PF01198.19 PVD34883.1 - 2.9e-44 149.2 2.0 4e-44 148.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 PVD34883.1 - 0.018 14.9 0.1 0.086 12.7 0.0 2.1 1 1 1 2 2 2 0 DNA mismatch endonuclease Vsr cNMP_binding PF00027.29 PVD34884.1 - 3.6e-06 27.0 0.0 0.0032 17.5 0.0 3.9 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain RCR PF12273.8 PVD34884.1 - 0.075 13.7 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red cNMP_binding PF00027.29 PVD34885.1 - 3.3e-17 62.3 0.1 2e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain HAT_KAT11 PF08214.11 PVD34886.1 - 1.7e-76 257.8 0.4 4.5e-76 256.4 0.4 1.8 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.16 PVD34886.1 - 1.9e-39 133.8 0.6 4.5e-39 132.6 0.6 1.7 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 PVD34886.1 - 4.5e-28 97.5 63.4 2.2e-19 69.7 16.3 3.8 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.13 PVD34886.1 - 1.2e-19 70.4 13.3 1.2e-19 70.4 13.3 2.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.25 PVD34886.1 - 3e-17 62.4 0.1 7.8e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 PVD34886.1 - 3.1e-12 46.1 13.3 3.1e-12 46.1 13.3 3.9 5 0 0 5 5 5 1 Zinc finger, ZZ type KIX_2 PF16987.5 PVD34886.1 - 8.1e-05 22.5 0.1 8.1e-05 22.5 0.1 3.6 3 0 0 3 3 3 1 KIX domain HEPN_RiboL-PSP PF18735.1 PVD34886.1 - 0.084 12.8 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 RiboL-PSP-HEPN FANCI_S3 PF14677.6 PVD34886.1 - 0.35 10.5 4.9 0.72 9.5 4.9 1.5 1 0 0 1 1 1 0 FANCI solenoid 3 Guanylate_cyc PF00211.20 PVD34887.1 - 4.6e-106 352.3 1.4 4e-60 202.6 0.0 2.7 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 PVD34887.1 - 7.7e-06 25.3 5.7 7.7e-06 25.3 5.7 2.7 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 PVD34887.1 - 0.0011 18.4 0.3 0.094 12.1 0.0 2.4 2 0 0 2 2 2 2 Heme NO binding associated Jnk-SapK_ap_N PF09744.9 PVD34888.1 - 5.8e-56 189.0 20.3 5.8e-56 189.0 20.3 5.1 6 0 0 6 6 6 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 PVD34888.1 - 2e-32 111.1 9.2 2e-32 111.1 9.2 5.6 4 1 1 5 5 5 1 JNK-interacting protein leucine zipper II ANAPC4_WD40 PF12894.7 PVD34888.1 - 0.049 13.9 0.2 0.27 11.6 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2833 PF11090.8 PVD34888.1 - 0.27 11.6 4.5 33 4.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2833) ApoO PF09769.9 PVD34888.1 - 0.63 10.0 3.6 28 4.7 0.2 3.4 2 1 0 2 2 2 0 Apolipoprotein O Herpes_UL6 PF01763.16 PVD34888.1 - 1.4 7.4 14.9 0.39 9.2 4.2 2.5 2 0 0 2 2 2 0 Herpesvirus UL6 like CheZ PF04344.13 PVD34888.1 - 4.2 7.2 23.8 0.19 11.7 1.3 3.5 4 0 0 4 4 4 0 Chemotaxis phosphatase, CheZ AtuA PF07287.11 PVD34889.1 - 2.7e-105 352.0 0.0 3.5e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Kinesin PF00225.23 PVD34890.1 - 1.9e-112 375.5 0.0 1.9e-112 375.5 0.0 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD34890.1 - 4.7e-23 81.8 0.0 3.4e-22 79.0 0.0 2.5 1 0 0 1 1 1 1 Microtubule binding DUF1643 PF07799.12 PVD34890.1 - 0.28 11.3 5.9 5.2 7.2 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1643) DUF3800 PF12686.7 PVD34890.1 - 0.37 11.4 3.1 1.3e+02 3.2 3.1 4.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) UcrQ PF02939.16 PVD34891.1 - 3.1e-31 107.1 0.1 3.4e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 PVD34891.1 - 0.14 12.6 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 COMM_domain PF07258.14 PVD34892.1 - 3e-15 56.1 1.0 3e-15 56.1 1.0 1.8 2 0 0 2 2 2 1 COMM domain SieB PF14163.6 PVD34892.1 - 0.0016 17.9 1.1 0.73 9.3 0.2 2.1 2 0 0 2 2 2 2 Super-infection exclusion protein B MgtE_N PF03448.17 PVD34892.1 - 0.014 16.0 0.2 0.12 13.0 0.1 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain PTP2 PF17022.5 PVD34892.1 - 0.014 15.0 5.7 0.73 9.4 2.0 2.2 1 1 1 2 2 2 0 Polar tube protein 2 from Microsporidia DUF3447 PF11929.8 PVD34892.1 - 0.018 15.0 0.2 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) FliG_N PF14842.6 PVD34892.1 - 0.02 15.4 1.9 6.1 7.4 0.1 2.8 1 1 1 2 2 2 0 FliG N-terminal domain DUF3194 PF11419.8 PVD34892.1 - 0.033 14.6 1.4 2.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3194) Sigma70_r4_2 PF08281.12 PVD34892.1 - 0.086 12.5 0.2 0.23 11.2 0.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 PhoLip_ATPase_C PF16212.5 PVD34893.1 - 2.5e-68 230.5 27.6 2.5e-68 230.5 27.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PVD34893.1 - 3.4e-23 81.1 1.0 3.4e-23 81.1 1.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PVD34893.1 - 2.6e-12 47.5 0.3 7.5e-07 29.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PVD34893.1 - 1.4e-07 31.2 0.4 2.3e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PVD34893.1 - 7e-05 22.7 0.0 0.00039 20.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 PVD34894.1 - 9.5e-15 54.8 2.7 0.0035 18.2 0.0 5.8 5 1 1 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 PVD34894.1 - 0.00082 19.8 0.0 22 5.7 0.0 4.2 4 0 0 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 PVD34894.1 - 0.0047 17.2 0.0 5.8 7.3 0.0 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD34894.1 - 0.089 11.4 0.0 0.29 9.7 0.0 1.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF1647 PF07801.11 PVD34895.1 - 1.1e-11 44.6 0.1 1.7e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Sulfotransfer_1 PF00685.27 PVD34898.1 - 3.9e-13 49.5 0.6 8.6e-13 48.4 0.3 1.6 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD34898.1 - 3.4e-06 27.6 0.0 0.0006 20.3 0.0 3.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD34898.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family PhrC_PhrF PF11131.8 PVD34898.1 - 0.35 10.5 0.9 0.76 9.4 0.9 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling Sulfotransfer_1 PF00685.27 PVD34899.1 - 9.8e-13 48.2 0.1 1.6e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD34899.1 - 1.4e-05 25.6 0.1 0.00012 22.6 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD34899.1 - 0.051 13.5 0.1 0.084 12.8 0.1 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD34900.1 - 1.5e-13 50.8 1.0 3.2e-13 49.8 1.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD34900.1 - 9.5e-06 26.1 0.7 0.00021 21.7 0.7 2.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD34900.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF3440 PF11922.8 PVD34900.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) zf_C2H2_ZHX PF18387.1 PVD34900.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3925 PF13063.6 PVD34900.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) Ub-RnfH PF03658.14 PVD34900.1 - 0.16 12.3 0.0 3.2 8.2 0.0 2.7 3 0 0 3 3 3 0 RnfH family Ubiquitin Collagen PF01391.18 PVD34901.1 - 5.3e-17 61.3 75.8 5.3e-06 26.1 35.4 4.3 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) SARAF PF06682.12 PVD34901.1 - 0.04 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Myosin_tail_1 PF01576.19 PVD34902.1 - 1e-75 255.4 161.8 1.3e-75 255.1 161.8 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 PVD34902.1 - 3e-09 36.9 145.5 0.012 15.2 7.5 8.8 1 1 4 6 6 6 4 Intermediate filament protein DUF1664 PF07889.12 PVD34902.1 - 3.6e-07 30.2 84.2 0.023 14.7 2.8 10.7 2 2 9 11 11 11 6 Protein of unknown function (DUF1664) Spc7 PF08317.11 PVD34902.1 - 8e-07 28.2 147.1 0.00057 18.9 31.3 7.6 1 1 6 7 7 7 5 Spc7 kinetochore protein KASH_CCD PF14662.6 PVD34902.1 - 0.00014 21.8 45.5 0.00049 20.0 22.9 8.6 1 1 5 7 7 7 3 Coiled-coil region of CCDC155 or KASH Nup54 PF13874.6 PVD34902.1 - 0.00023 21.3 7.4 0.00023 21.3 7.4 9.3 1 1 7 8 8 5 1 Nucleoporin complex subunit 54 DUF4472 PF14739.6 PVD34902.1 - 0.00069 20.3 10.0 0.00069 20.3 10.0 11.2 1 1 10 12 12 12 1 Domain of unknown function (DUF4472) DUF4201 PF13870.6 PVD34902.1 - 0.00077 19.2 8.1 0.00077 19.2 8.1 9.2 3 2 6 10 10 9 1 Domain of unknown function (DUF4201) Tropomyosin PF00261.20 PVD34902.1 - 0.0011 18.4 22.5 0.0011 18.4 22.5 8.9 1 1 4 7 7 5 3 Tropomyosin ATG16 PF08614.11 PVD34902.1 - 0.0012 19.1 173.9 0.0071 16.6 34.4 8.4 1 1 5 7 7 7 4 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 PVD34902.1 - 0.0015 18.2 161.0 0.0048 16.6 38.5 7.8 3 1 4 7 7 7 4 Ciliary protein causing Leber congenital amaurosis disease SHE3 PF17078.5 PVD34902.1 - 0.0085 15.8 120.2 0.14 11.9 16.5 6.7 2 1 5 7 7 7 5 SWI5-dependent HO expression protein 3 HALZ PF02183.18 PVD34902.1 - 0.028 14.6 0.7 0.028 14.6 0.7 13.4 12 3 1 14 14 13 0 Homeobox associated leucine zipper DUF3800 PF12686.7 PVD34902.1 - 0.1 13.2 4.1 2.5e+02 2.3 4.1 4.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF3450 PF11932.8 PVD34902.1 - 0.16 11.2 133.4 0.11 11.8 5.2 9.7 1 1 7 9 9 9 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 PVD34902.1 - 0.34 11.0 169.5 0.033 14.3 10.1 11.5 1 1 9 10 10 9 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 PVD34902.1 - 1.2 9.3 152.7 0.049 13.7 13.3 11.5 2 2 11 13 13 13 0 Afadin- and alpha -actinin-Binding MbeD_MobD PF04899.12 PVD34902.1 - 1.5 9.0 66.7 0.1 12.8 0.8 11.1 5 5 3 10 10 10 0 MbeD/MobD like AAA_13 PF13166.6 PVD34902.1 - 9.1 4.8 114.0 0.036 12.7 33.7 5.0 1 1 2 4 4 3 0 AAA domain DUF2464 PF10240.9 PVD34905.1 - 0.0078 15.8 0.1 0.0091 15.6 0.1 1.1 1 0 0 1 1 1 1 Multivesicular body subunit 12 DUF1115 PF06544.12 PVD34906.1 - 5.1e-14 52.6 0.0 1e-13 51.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 PVD34906.1 - 2.8e-09 37.3 0.0 4.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain AMOP PF03782.17 PVD34907.1 - 9.2e-32 110.1 11.7 6.8e-29 100.8 11.7 2.4 1 1 0 1 1 1 1 AMOP domain VWD PF00094.25 PVD34907.1 - 6.6e-14 52.5 1.4 2.7e-13 50.5 0.1 2.8 4 1 0 4 4 4 1 von Willebrand factor type D domain NIDO PF06119.14 PVD34907.1 - 1.8e-05 25.6 0.0 4.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Nidogen-like DUF4192 PF13830.6 PVD34909.1 - 0.017 15.2 2.6 0.019 15.0 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Kdo PF06293.14 PVD34910.1 - 0.099 12.0 0.1 0.18 11.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trp_dioxygenase PF03301.13 PVD34911.1 - 9.5e-84 281.7 3.3 6.9e-73 246.0 0.7 2.1 2 0 0 2 2 2 2 Tryptophan 2,3-dioxygenase NDUF_B5 PF09781.9 PVD34911.1 - 0.0032 17.1 0.1 0.0094 15.6 0.2 1.7 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit pKID PF02173.17 PVD34911.1 - 0.0088 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 pKID domain Aa_trans PF01490.18 PVD34912.1 - 4.3e-79 266.1 16.8 5.2e-79 265.9 16.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L37e PF01907.19 PVD34912.1 - 0.15 12.2 0.3 0.29 11.3 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e DUF2937 PF11157.8 PVD34915.1 - 0.065 13.0 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF316 PF03761.15 PVD34915.1 - 0.1 12.2 0.3 0.13 11.8 0.3 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 COX6C PF02937.15 PVD34915.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc Tubulin PF00091.25 PVD34917.1 - 2.2e-31 109.6 0.7 3.2e-18 66.6 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.25 PVD34918.1 - 4.3e-55 187.0 0.0 5.3e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 PVD34918.1 - 0.00055 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain GH3 PF03321.13 PVD34919.1 - 3.3e-106 356.2 0.0 4.1e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter RhoGAP PF00620.27 PVD34920.1 - 1.5e-38 132.0 0.0 3.6e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain ArfGap PF01412.18 PVD34920.1 - 4e-35 120.4 2.1 2.5e-34 117.8 0.9 2.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 PVD34920.1 - 1e-32 112.8 9.8 2.7e-14 53.6 0.0 5.6 6 0 0 6 6 6 4 PH domain PH_11 PF15413.6 PVD34920.1 - 0.00055 20.3 7.6 0.11 13.0 0.0 5.7 5 2 0 5 5 5 1 Pleckstrin homology domain PH_13 PF16652.5 PVD34920.1 - 0.001 18.9 2.0 0.66 9.8 0.0 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH_16 PF17838.1 PVD34920.1 - 0.0067 16.3 0.3 0.068 13.0 0.0 2.6 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 PVD34920.1 - 2.5 8.5 4.8 7.4 7.0 0.0 4.1 5 0 0 5 5 5 0 Pleckstrin homology domain Med29 PF11568.8 PVD34921.1 - 0.16 12.2 0.0 0.66 10.2 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 29 AA_permease_2 PF13520.6 PVD34922.1 - 3e-64 217.4 43.3 3.5e-64 217.2 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PVD34922.1 - 1.5e-30 106.3 34.0 1.5e-30 106.3 34.0 1.4 2 0 0 2 2 2 1 Amino acid permease Ras PF00071.22 PVD34924.1 - 6.4e-58 194.9 0.0 7.4e-58 194.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD34924.1 - 6.7e-36 123.1 0.0 9.6e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD34924.1 - 2.1e-13 50.1 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD34924.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD34924.1 - 3.3e-05 23.9 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD34924.1 - 5.7e-05 22.7 0.0 0.00046 19.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD34924.1 - 0.00098 19.1 0.1 0.89 9.4 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PVD34924.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 PVD34924.1 - 0.0012 18.4 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 PVD34924.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD34924.1 - 0.048 13.9 0.2 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 PVD34924.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_33 PF13671.6 PVD34924.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD34924.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PVD34924.1 - 0.14 12.6 0.0 0.47 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD34924.1 - 0.14 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 PVD34924.1 - 0.17 10.8 0.0 0.85 8.5 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 PVD34924.1 - 0.25 11.1 1.3 18 5.0 0.2 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CTD_bind PF04818.13 PVD34925.1 - 3.6e-05 24.5 0.1 8.4e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Exo_endo_phos PF03372.23 PVD34926.1 - 2.7e-20 72.9 0.0 6.3e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PVD34926.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Pirin PF02678.16 PVD34927.1 - 3e-31 107.6 0.0 6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 PVD34927.1 - 6.4e-28 97.2 0.0 3.8e-27 94.7 0.0 2.2 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 PVD34927.1 - 0.02 14.6 0.6 0.36 10.6 0.1 2.9 3 0 0 3 3 3 0 Cupin domain THOC2_N PF16134.5 PVD34928.1 - 2.6e-85 287.3 3.6 9.1e-38 130.3 0.4 5.0 3 2 2 5 5 5 3 THO complex subunit 2 N-terminus Tho2 PF11262.8 PVD34928.1 - 2.6e-80 269.8 8.1 5.1e-77 259.0 8.6 3.5 2 1 1 3 3 3 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 PVD34928.1 - 5.3e-34 116.1 0.1 1.4e-33 114.7 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit TPR_19 PF14559.6 PVD34928.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 PVD34929.1 - 2e-17 64.0 0.0 4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 PVD34929.1 - 8.8e-13 48.7 0.0 2.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD34929.1 - 2.8e-10 40.8 0.0 7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 PVD34929.1 - 1.5e-07 31.1 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_8 PF05148.15 PVD34929.1 - 3.2e-05 23.9 0.0 5.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 PVD34929.1 - 0.0002 21.2 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD34929.1 - 0.0013 18.6 0.0 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD34929.1 - 0.0022 17.4 0.0 0.017 14.4 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-C2H2 PF00096.26 PVD34930.1 - 1.1e-18 66.5 46.9 0.0016 18.8 0.6 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD34930.1 - 1.3e-17 62.9 43.4 0.005 17.6 0.8 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD34930.1 - 1.2e-15 57.1 38.6 0.00015 22.0 0.1 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 PVD34930.1 - 4.2e-06 26.6 19.5 0.00029 20.8 1.0 7.0 7 1 0 7 7 5 4 C2H2-type zinc finger zf-Di19 PF05605.12 PVD34930.1 - 1.4e-05 25.2 1.2 1.4e-05 25.2 1.2 4.2 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PVD34930.1 - 0.00013 22.2 34.9 0.018 15.4 1.2 6.1 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 PVD34930.1 - 0.0021 17.7 2.7 0.0021 17.7 2.7 4.4 3 1 2 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 PVD34930.1 - 0.0035 17.7 30.2 0.036 14.5 0.5 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 PVD34930.1 - 0.0069 16.5 18.5 0.3 11.2 4.0 4.2 4 0 0 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 PVD34930.1 - 0.32 10.6 0.1 0.32 10.6 0.1 6.3 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger AT_hook PF02178.19 PVD34930.1 - 0.73 9.9 11.7 1 9.4 2.2 2.7 2 0 0 2 2 2 0 AT hook motif DZR PF12773.7 PVD34930.1 - 6.8 6.8 19.3 0.13 12.3 0.3 3.5 2 1 0 2 2 1 0 Double zinc ribbon ADK_lid PF05191.14 PVD34930.1 - 9.9 6.2 19.8 3.2 7.8 2.2 3.8 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 PVD34931.1 - 2.5e-32 109.5 64.7 0.00077 19.8 0.3 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD34931.1 - 4.6e-31 105.8 55.7 3.3e-05 24.1 0.0 10.8 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD34931.1 - 1.6e-30 103.1 63.2 0.0005 20.7 0.5 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD34931.1 - 1e-16 60.7 44.0 0.013 15.7 0.2 9.6 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD34931.1 - 1.8e-12 47.2 49.5 0.053 13.9 0.5 9.5 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD34931.1 - 2.4e-11 43.3 60.9 0.00015 21.7 1.0 9.6 9 1 0 9 9 8 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 PVD34931.1 - 2.3e-06 27.6 29.6 0.017 15.3 2.5 5.7 4 2 2 6 6 6 3 Zinc ribbon domain zf-C2H2_11 PF16622.5 PVD34931.1 - 3.9e-06 26.5 36.8 4.3e-05 23.2 0.4 7.1 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-Di19 PF05605.12 PVD34931.1 - 2.3e-05 24.6 2.9 2.3e-05 24.6 2.9 5.9 3 2 3 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 PVD34931.1 - 0.00017 21.1 33.2 0.54 9.9 0.2 8.5 9 0 0 9 9 9 3 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 PVD34931.1 - 0.0013 18.6 36.6 0.47 10.4 0.2 8.3 8 0 0 8 8 8 4 zinc-finger of a C2HC-type PhnA_Zn_Ribbon PF08274.12 PVD34931.1 - 0.0032 17.4 0.1 4.5 7.3 0.0 5.1 6 1 0 6 6 6 1 PhnA Zinc-Ribbon zf-C2H2_8 PF15909.5 PVD34931.1 - 0.0074 16.6 34.6 0.22 11.8 6.1 5.0 1 1 2 4 4 4 2 C2H2-type zinc ribbon DUF2256 PF10013.9 PVD34931.1 - 0.0095 16.0 25.6 6.7 6.9 0.1 8.1 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 PVD34931.1 - 0.012 16.4 24.5 4.7 8.0 0.3 5.2 2 1 1 5 5 5 0 zinc-ribbon family DZR PF12773.7 PVD34931.1 - 0.036 14.1 24.7 0.35 10.9 0.2 4.5 3 2 0 3 3 3 0 Double zinc ribbon zf-C2H2_2 PF12756.7 PVD34931.1 - 0.071 13.5 41.3 4 7.8 0.1 7.4 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 PVD34931.1 - 0.22 11.6 0.1 0.22 11.6 0.1 5.2 6 1 1 7 7 5 0 Zic proteins zinc finger domain HypA PF01155.19 PVD34931.1 - 0.37 10.8 22.6 1.6 8.8 1.2 4.5 1 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Chordopox_RPO7 PF05864.12 PVD34931.1 - 0.65 10.3 6.5 8.2 6.8 0.0 4.0 5 0 0 5 5 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-H2C2_5 PF13909.6 PVD34931.1 - 0.91 9.3 39.1 0.75 9.6 4.9 8.1 8 0 0 8 8 8 0 C2H2-type zinc-finger domain DUF2180 PF09947.9 PVD34931.1 - 1.3 9.0 8.2 9.6 6.3 1.5 3.5 3 0 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2180) ADK_lid PF05191.14 PVD34931.1 - 3.7 7.6 28.2 1.1 9.3 1.9 6.4 5 2 2 7 7 7 0 Adenylate kinase, active site lid zf-MYST PF17772.1 PVD34931.1 - 6.7 6.4 28.7 6.3 6.5 0.1 8.1 7 1 2 9 9 9 0 MYST family zinc finger domain Spt46 PF17734.1 PVD34931.1 - 6.9 6.4 19.1 0.97 9.2 0.2 4.8 2 2 2 5 5 5 0 Spermatogenesis-associated protein 46 IgGFc_binding PF17517.2 PVD34932.1 - 9.3e-18 64.5 1.4 6.6e-16 58.4 0.0 2.4 2 1 0 2 2 2 2 IgGFc binding protein IgGFc_binding PF17517.2 PVD34933.1 - 1.7e-37 129.3 10.8 1.7e-37 129.3 10.8 3.1 2 1 1 3 3 3 2 IgGFc binding protein Cu-binding_MopE PF11617.8 PVD34933.1 - 0.0004 20.5 22.6 0.0041 17.3 2.6 3.2 3 0 0 3 3 3 2 Putative metal-binding motif Ank_2 PF12796.7 PVD34935.1 - 1.9e-48 163.0 3.9 4.2e-14 52.9 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD34935.1 - 9.8e-39 131.3 1.2 5.9e-10 39.5 0.0 8.6 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD34935.1 - 2.4e-34 116.3 8.0 6.4e-05 23.2 0.1 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PVD34935.1 - 1.2e-27 95.5 5.3 7.6e-05 22.9 0.0 8.0 6 2 1 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD34935.1 - 6.5e-27 90.6 2.6 0.00093 19.5 0.0 10.3 11 1 0 11 11 11 5 Ankyrin repeat SOCS_box PF07525.16 PVD34935.1 - 0.00037 20.8 1.5 0.00046 20.5 0.2 1.8 2 0 0 2 2 2 1 SOCS box PhoLip_ATPase_C PF16212.5 PVD34936.1 - 2.2e-87 293.0 22.8 2.2e-87 293.0 22.8 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PVD34936.1 - 3.9e-25 87.3 7.1 3.9e-25 87.3 7.1 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal SAP30_Sin3_bdg PF13867.6 PVD34936.1 - 8.9e-20 70.8 0.5 2.1e-19 69.6 0.5 1.7 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Cation_ATPase PF13246.6 PVD34936.1 - 7.1e-13 48.5 0.0 4.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PVD34936.1 - 4.5e-08 33.6 0.1 0.055 13.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PVD34936.1 - 1.9e-07 30.8 0.1 1.8e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PVD34936.1 - 0.016 15.0 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 PVD34937.1 - 3e-19 69.8 0.1 7.1e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PVD34937.1 - 3.2e-10 39.9 0.0 8.2e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NHL PF01436.21 PVD34938.1 - 1e-20 72.6 18.8 1.3e-08 34.5 0.5 6.7 8 0 0 8 8 7 3 NHL repeat zf-B_box PF00643.24 PVD34938.1 - 5.9e-10 39.1 26.5 3.9e-08 33.3 11.0 4.8 5 0 0 5 5 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD34938.1 - 7.6e-08 32.3 3.2 7.6e-08 32.3 3.2 3.7 6 0 0 6 6 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD34938.1 - 9.6e-07 28.6 3.6 9.6e-07 28.6 3.6 4.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD34938.1 - 1.8e-06 27.7 8.7 1.8e-06 27.7 8.7 4.4 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD34938.1 - 0.00014 21.8 7.5 0.00014 21.8 7.5 4.7 5 0 0 5 5 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD34938.1 - 0.00033 20.7 7.6 0.00033 20.7 7.6 4.7 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD34938.1 - 0.00085 19.6 7.3 0.00085 19.6 7.3 4.1 4 0 0 4 4 3 1 Ring finger domain DUF5128 PF17170.4 PVD34938.1 - 0.00099 18.3 1.7 0.14 11.2 0.2 3.1 2 1 1 3 3 3 1 6-bladed beta-propeller Prok-RING_4 PF14447.6 PVD34938.1 - 0.0031 17.3 4.0 0.0031 17.3 4.0 4.6 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PVD34938.1 - 0.0057 16.5 9.5 0.0057 16.5 9.5 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Ecm29 PF13001.7 PVD34938.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser SGL PF08450.12 PVD34938.1 - 0.053 13.1 0.1 12 5.4 0.0 3.3 2 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region FliT PF05400.13 PVD34938.1 - 6.5 7.6 6.2 7.3 7.5 4.9 1.8 2 0 0 2 2 1 0 Flagellar protein FliT RFXA_RFXANK_bdg PF15289.6 PVD34939.1 - 2.6e-11 43.9 2.7 9.6e-11 42.1 2.7 2.0 1 1 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain FH2 PF02181.23 PVD34942.1 - 2.8e-87 293.2 8.8 6.3e-87 292.1 8.8 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PVD34942.1 - 4.5e-24 85.2 0.2 4.5e-24 85.2 0.2 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain TMF_TATA_bd PF12325.8 PVD34942.1 - 0.071 13.3 4.5 5.1 7.3 0.2 3.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 PVD34942.1 - 0.22 12.0 6.3 0.15 12.5 1.3 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3972 PF13118.6 PVD34942.1 - 0.23 11.9 3.5 0.65 10.4 1.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) Baculo_PEP_C PF04513.12 PVD34942.1 - 0.35 10.9 3.0 1.3 9.1 0.3 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACCA PF03255.14 PVD34942.1 - 6.4 6.6 8.3 0.48 10.3 0.2 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CRAL_TRIO PF00650.20 PVD34943.1 - 3.6e-28 98.3 0.2 6.5e-28 97.4 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain RNase_H PF00075.24 PVD34943.1 - 5.9e-12 46.0 0.0 1.4e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 RNase H CRAL_TRIO_2 PF13716.6 PVD34943.1 - 0.006 16.7 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RVT_3 PF13456.6 PVD34943.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like OS-D PF03392.13 PVD34943.1 - 0.14 12.2 0.4 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D PID PF00640.23 PVD34945.1 - 5.5e-34 117.2 0.0 4.9e-27 94.7 0.0 2.8 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD34945.1 - 2.4e-05 24.5 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotyrosine-binding domain WW PF00397.26 PVD34945.1 - 6.5e-05 22.9 1.9 0.00013 22.0 1.9 1.5 1 0 0 1 1 1 1 WW domain AF-4 PF05110.13 PVD34946.1 - 1.7e-69 235.2 74.1 1.7e-69 235.2 74.1 2.1 2 0 0 2 2 2 2 AF-4 proto-oncoprotein DUF3413 PF11893.8 PVD34947.1 - 1.3 8.2 9.2 0.25 10.5 5.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Keratin_assoc PF09775.9 PVD34948.1 - 0.07 12.8 3.2 0.41 10.3 0.5 2.4 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 WTF PF03303.13 PVD34948.1 - 0.085 12.6 5.6 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 WTF protein PIG-P PF08510.12 PVD34948.1 - 0.68 9.9 3.6 0.9 9.5 0.0 2.5 2 1 0 2 2 2 0 PIG-P GWT1 PF06423.12 PVD34948.1 - 2.1 8.5 4.1 23 5.1 0.0 3.0 1 1 1 3 3 3 0 GWT1 DUF2207 PF09972.9 PVD34948.1 - 3.2 6.4 8.8 3.7 6.2 2.0 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3112 PF11309.8 PVD34948.1 - 3.4 7.1 5.9 2.1 7.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) PUA PF01472.20 PVD34949.1 - 2.4e-16 59.4 0.9 7.7e-16 57.8 0.1 2.3 3 0 0 3 3 3 1 PUA domain Methyltr_RsmB-F PF01189.17 PVD34949.1 - 0.0012 18.5 4.8 0.0013 18.4 1.4 2.5 2 1 1 3 3 3 1 16S rRNA methyltransferase RsmB/F DUF5068 PF16781.5 PVD34949.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Ets PF00178.22 PVD34952.1 - 1.6e-34 118.2 0.7 2.6e-34 117.5 0.7 1.3 1 0 0 1 1 1 1 Ets-domain GPR15L PF15854.5 PVD34954.1 - 0.42 10.9 2.6 0.31 11.3 0.6 1.8 1 1 1 2 2 2 0 G-protein coupled receptor ligand 15 Pkinase_Tyr PF07714.17 PVD34956.1 - 3.3e-60 203.6 0.0 1.6e-59 201.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD34956.1 - 6e-23 81.5 0.2 2.1e-11 43.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 PVD34956.1 - 0.0058 15.6 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PRIMA1 PF16101.5 PVD34956.1 - 0.034 14.2 0.0 0.034 14.2 0.0 2.2 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Shisa PF13908.6 PVD34956.1 - 0.044 14.0 1.8 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 PVD34956.1 - 0.12 12.3 0.3 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_Tyr PF07714.17 PVD34959.1 - 8.3e-73 244.9 0.1 1.3e-71 240.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 PVD34959.1 - 2.5e-46 156.2 6.1 2.4e-15 56.9 0.0 7.9 7 1 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 PVD34959.1 - 5.1e-42 141.8 0.1 3.7e-14 52.5 0.0 6.3 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD34959.1 - 2.1e-31 108.1 4.5 8.6e-10 38.8 0.0 7.9 8 1 0 8 8 8 5 Immunoglobulin domain Pkinase PF00069.25 PVD34959.1 - 4e-28 98.5 0.0 8.5e-28 97.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain ig PF00047.25 PVD34959.1 - 2e-24 85.5 0.2 0.00032 20.8 0.0 7.6 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 PVD34959.1 - 4.6e-11 42.9 8.1 0.27 11.4 0.1 8.0 6 2 1 8 8 8 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD34959.1 - 3e-09 36.8 0.0 0.0076 16.3 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD34959.1 - 0.00018 21.5 0.3 7.9 6.6 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD34959.1 - 0.0008 18.9 4.7 3.4 7.3 0.1 4.9 5 0 0 5 5 5 2 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD34959.1 - 0.0075 16.5 0.0 18 5.6 0.0 3.8 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Pkinase_fungal PF17667.1 PVD34959.1 - 0.026 13.3 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase G6B PF15096.6 PVD34959.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 G6B family RhoGAP PF00620.27 PVD34960.1 - 9.9e-36 122.9 0.1 2.1e-35 121.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 PVD34960.1 - 5e-31 107.8 0.1 8.3e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 START domain SAM_2 PF07647.17 PVD34962.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD34962.1 - 0.12 12.8 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PAS_3 PF08447.12 PVD34963.1 - 5.1e-18 65.2 0.0 2.5e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 PVD34963.1 - 5.5e-18 65.1 3.9 8.2e-15 54.9 0.1 2.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 PVD34963.1 - 5.8e-14 52.1 0.0 4.2e-06 26.7 0.0 2.9 2 2 1 3 3 3 2 PAS fold PAS_4 PF08448.10 PVD34963.1 - 2.5e-08 34.1 0.0 0.029 14.6 0.0 3.3 2 1 1 3 3 3 2 PAS fold PAS_9 PF13426.7 PVD34963.1 - 7.2e-06 26.2 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 PVD34963.1 - 0.029 15.0 0.1 0.086 13.5 0.1 1.8 1 0 0 1 1 1 0 PAS fold DrrA_P4M PF14860.6 PVD34963.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Uds1 PF15456.6 PVD34964.1 - 0.013 15.7 1.8 0.024 14.8 1.8 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF4404 PF14357.6 PVD34964.1 - 1.1 9.9 5.7 1.5 9.5 4.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) MFS_1 PF07690.16 PVD34965.1 - 2.5e-15 56.3 18.8 1.9e-07 30.3 12.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 PVD34965.1 - 0.068 13.1 15.5 0.021 14.7 9.1 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling TIM21 PF08294.11 PVD34965.1 - 0.18 11.7 2.2 0.7 9.8 0.8 2.4 2 0 0 2 2 2 0 TIM21 DUF1700 PF08006.11 PVD34965.1 - 0.75 9.3 7.1 1.5 8.4 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Abhydrolase_9_N PF15420.6 PVD34965.1 - 0.88 9.5 8.2 1.3 8.9 1.8 3.0 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus Frag1 PF10277.9 PVD34965.1 - 1.8 8.0 13.2 0.83 9.1 8.3 2.3 2 1 0 2 2 2 0 Frag1/DRAM/Sfk1 family DUF4131 PF13567.6 PVD34965.1 - 3.2 7.4 14.5 1.9 8.1 3.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 PVD34966.1 - 0.016 14.2 2.0 0.02 13.8 2.0 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily TED_complement PF07678.14 PVD34967.1 - 5.7e-25 88.0 0.0 1.1e-23 83.7 0.0 2.0 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 PVD34967.1 - 1.4e-22 80.2 0.1 2.9e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain TonB_N PF16031.5 PVD34969.1 - 0.17 12.4 2.1 0.27 11.7 0.1 2.0 2 0 0 2 2 2 0 TonB polyproline region CUE PF02845.16 PVD34970.1 - 0.042 13.6 0.1 50 3.7 0.0 3.2 3 0 0 3 3 3 0 CUE domain A2M_BRD PF07703.14 PVD34971.1 - 9.3e-20 71.4 5.2 8.8e-16 58.5 2.3 4.1 3 1 0 3 3 3 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD34971.1 - 1.1e-15 57.6 0.1 4.2e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD34971.1 - 2.9e-11 43.7 0.1 2.3e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 MG2 domain MG1 PF17790.1 PVD34971.1 - 0.00058 20.2 0.4 0.0026 18.1 0.1 2.2 2 0 0 2 2 2 1 Macroglobulin domain MG1 Glyco_hydro_66 PF13199.6 PVD34971.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 MG4 PF17789.1 PVD34971.1 - 9.1 6.5 6.5 7.9 6.7 0.1 3.9 5 1 0 5 5 5 0 Macroglobulin domain MG4 potato_inhibit PF00280.18 PVD34972.1 - 3.4e-22 78.9 0.1 3.8e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 PVD34972.1 - 0.0029 17.6 0.0 0.0036 17.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family adh_short PF00106.25 PVD34973.1 - 1.6e-31 109.3 1.0 5e-23 81.6 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD34973.1 - 1.5e-19 70.5 1.8 4.1e-18 65.8 1.8 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 PVD34973.1 - 2.2e-12 47.5 0.0 1e-10 42.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD34973.1 - 9.1e-11 42.3 0.0 9.3e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.10 PVD34973.1 - 1.2e-09 38.4 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 KR domain UPF0016 PF01169.19 PVD34973.1 - 6.4e-09 36.0 7.6 8.5e-05 22.8 4.1 2.8 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Epimerase PF01370.21 PVD34973.1 - 1e-06 28.4 0.1 5e-06 26.1 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 PVD34973.1 - 1.8e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD34973.1 - 2.9e-05 24.7 0.0 7.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PVD34973.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 PVD34973.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain OFeT_1 PF16955.5 PVD34973.1 - 0.0024 17.6 0.8 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter Cad PF03596.13 PVD34973.1 - 0.0077 16.1 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Cadmium resistance transporter CMAS PF02353.20 PVD34973.1 - 0.0096 15.2 0.0 0.36 10.1 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 PVD34973.1 - 0.0097 15.3 0.1 0.042 13.2 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB GDP_Man_Dehyd PF16363.5 PVD34973.1 - 0.012 15.0 0.2 0.089 12.2 0.0 2.3 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase TadF PF16964.5 PVD34973.1 - 0.034 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF1508 PF07411.12 PVD34973.1 - 0.078 12.8 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) SpoIIM PF01944.17 PVD34973.1 - 1.3 9.0 8.5 0.29 11.2 3.7 2.4 2 2 0 2 2 2 0 Stage II sporulation protein M tRNA-synt_His PF13393.6 PVD34974.1 - 1.1e-43 149.7 0.0 2e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 PVD34974.1 - 3.8e-16 59.0 0.5 9.9e-16 57.7 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 PVD34974.1 - 1.5e-13 50.7 5.0 4.5e-13 49.1 5.0 1.9 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 PVD34974.1 - 6.4e-07 29.1 0.1 2e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 PVD34974.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 PVD34974.1 - 0.017 14.2 0.0 0.04 13.0 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) PHR PF08005.12 PVD34975.1 - 1.2e-82 275.9 0.0 4.9e-41 140.9 0.0 2.9 2 0 0 2 2 2 2 PHR domain RCC1 PF00415.18 PVD34975.1 - 7.9e-24 84.0 16.8 1.2e-13 51.5 0.1 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD34975.1 - 5.5e-22 77.0 14.1 4.2e-09 36.0 1.7 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat SH3_3 PF08239.11 PVD34975.1 - 3.6e-16 59.2 0.1 7.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain zf-RING_2 PF13639.6 PVD34975.1 - 1.3e-08 35.0 3.8 1.3e-08 35.0 3.8 6.1 7 0 0 7 7 7 1 Ring finger domain Filamin PF00630.19 PVD34975.1 - 2.1e-05 25.2 0.1 0.00028 21.6 0.0 2.7 2 0 0 2 2 2 1 Filamin/ABP280 repeat zf-rbx1 PF12678.7 PVD34975.1 - 0.0011 19.2 2.1 0.0011 19.2 2.1 4.2 3 0 0 3 3 3 1 RING-H2 zinc finger domain ANAPC10 PF03256.16 PVD34975.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) zf-RING_11 PF17123.5 PVD34975.1 - 1.7 8.5 19.2 0.0064 16.2 5.6 3.7 3 0 0 3 3 3 0 RING-like zinc finger AAA_30 PF13604.6 PVD34976.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PVD34976.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD34976.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 PVD34976.1 - 0.051 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PVD34976.1 - 0.059 12.9 0.3 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD34976.1 - 0.06 12.5 0.3 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 PVD34976.1 - 0.068 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD34976.1 - 0.11 12.8 0.0 0.4 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.6 PVD34976.1 - 0.12 12.2 0.1 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 PVD34976.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PVD34976.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Foie-gras_1 PF11817.8 PVD34977.1 - 7.8e-68 228.9 0.5 1.3e-67 228.1 0.5 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 PVD34977.1 - 7.3e-16 58.1 0.5 4e-11 42.4 0.4 2.6 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 PVD34977.1 - 3.4e-13 49.4 0.0 8.2e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 PVD34977.1 - 0.034 13.9 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 2-Hacid_dh_C PF02826.19 PVD34978.1 - 5.8e-58 195.2 0.0 8.4e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD34978.1 - 4.2e-33 113.8 0.0 4.9e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PVD34978.1 - 0.0039 17.4 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 PVD34978.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 PVD34978.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 PVD34978.1 - 0.14 11.5 0.2 0.38 10.1 0.1 1.7 2 0 0 2 2 2 0 ThiF family Tox-GHH PF15636.6 PVD34979.1 - 1e-27 95.9 0.1 2.1e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 PVD34979.1 - 0.0049 17.3 0.5 0.032 14.7 0.1 2.7 2 0 0 2 2 2 1 RHS Repeat Tcp10_C PF07202.13 PVD34979.1 - 0.019 14.9 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Reo_sigmaC PF04582.12 PVD34979.1 - 0.039 14.2 0.3 0.52 10.6 0.0 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain Nucleic_acid_bd PF13820.6 PVD34979.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.8 1 1 1 2 2 2 0 Putative nucleic acid-binding region NHL PF01436.21 PVD34980.1 - 3.5e-10 39.4 4.8 0.0036 17.3 0.0 6.4 7 0 0 7 7 7 3 NHL repeat RHS_repeat PF05593.14 PVD34980.1 - 4.2e-08 33.5 4.3 0.063 13.8 0.0 7.7 7 1 1 8 8 8 2 RHS Repeat EGF PF00008.27 PVD34980.1 - 6.7e-05 23.1 5.5 6.7e-05 23.1 5.5 2.3 2 0 0 2 2 2 1 EGF-like domain CarboxypepD_reg PF13620.6 PVD34980.1 - 0.00073 19.8 0.2 0.0031 17.7 0.1 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF839 PF05787.13 PVD34980.1 - 0.042 13.0 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF839) DUF4596 PF15363.6 PVD34980.1 - 0.045 14.0 2.2 0.073 13.3 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) EGF_2 PF07974.13 PVD34981.1 - 4.1e-14 52.6 50.3 3.9e-05 23.9 11.1 3.4 3 0 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 PVD34981.1 - 8.4e-08 32.1 37.1 0.00027 20.9 11.3 3.4 3 0 0 3 3 3 3 Tenascin EGF domain hEGF PF12661.7 PVD34981.1 - 0.025 15.2 8.4 0.025 15.2 8.4 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF I-EGF_1 PF18372.1 PVD34981.1 - 0.033 14.3 36.4 0.3 11.2 6.9 3.5 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 PVD34981.1 - 0.41 10.8 40.8 6.4 7.0 6.7 3.4 1 1 2 3 3 3 0 Laminin EGF domain EGF PF00008.27 PVD34981.1 - 2.3 8.6 49.5 0.22 11.9 10.0 4.3 4 1 0 4 4 4 0 EGF-like domain EB PF01683.18 PVD34981.1 - 4.9 7.5 34.1 49 4.3 16.3 3.4 1 1 2 3 3 3 0 EB module Kinesin PF00225.23 PVD34987.1 - 5.6e-123 410.1 0.0 1.5e-122 408.7 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD34987.1 - 5.2e-26 91.4 0.0 5.2e-26 91.4 0.0 2.7 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 PVD34987.1 - 0.29 11.4 8.5 1.3 9.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PVD34987.1 - 0.9 9.9 0.0 0.9 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain APG6_N PF17675.1 PVD34987.1 - 8.1 7.0 59.1 0.26 11.8 24.8 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 PVD34988.1 - 1.3e-30 105.0 0.4 6.2e-18 64.4 0.0 4.3 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 PVD34988.1 - 0.18 11.5 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated cNMP_binding PF00027.29 PVD34989.1 - 6.7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TIMP PF00965.17 PVD34990.1 - 2.4e-08 34.0 0.0 2.9e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase TIMP PF00965.17 PVD34992.1 - 0.091 12.6 0.1 0.098 12.5 0.1 1.1 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase TIMP PF00965.17 PVD34993.1 - 5.4e-12 45.9 2.3 3.6e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Tissue inhibitor of metalloproteinase ATP_synt_H PF05493.13 PVD34993.1 - 3.2 8.3 13.6 0.35 11.4 0.5 2.7 2 0 0 2 2 2 0 ATP synthase subunit H TIMP PF00965.17 PVD34994.1 - 5.8e-11 42.5 0.1 7.1e-11 42.2 0.1 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase A2M_BRD PF07703.14 PVD34995.1 - 2.1e-27 96.2 0.5 5.4e-27 94.8 0.5 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain MG4 PF17789.1 PVD34995.1 - 1.1e-07 31.9 1.5 1.7e-06 28.1 0.2 3.3 3 1 0 3 3 3 1 Macroglobulin domain MG4 TED_complement PF07678.14 PVD34996.1 - 7.9e-59 199.2 0.0 2.5e-42 145.0 0.0 2.1 2 0 0 2 2 2 2 A-macroglobulin TED domain A2M_recep PF07677.14 PVD34996.1 - 2.9e-05 24.7 0.0 9.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain SQHop_cyclase_C PF13243.6 PVD34996.1 - 8.1e-05 21.9 0.0 0.00034 19.8 0.0 1.8 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 PVD34996.1 - 0.00098 18.8 0.0 0.054 13.2 0.0 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat RED_C PF07807.11 PVD34997.1 - 5.3e-32 110.6 5.3 8.3e-32 110.0 5.3 1.3 1 0 0 1 1 1 1 RED-like protein C-terminal region RED_N PF07808.13 PVD34997.1 - 1.3e-23 83.8 0.1 1.3e-23 83.8 0.1 1.8 1 1 1 2 2 2 1 RED-like protein N-terminal region HMMR_C PF15908.5 PVD34998.1 - 3.4e-26 92.4 14.7 3.4e-26 92.4 14.7 7.7 2 1 4 7 7 7 1 Hyaluronan mediated motility receptor C-terminal HMMR_N PF15905.5 PVD34998.1 - 3e-12 46.7 59.8 3e-12 46.7 59.8 5.4 1 1 4 6 6 6 1 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 PVD34998.1 - 0.0044 17.3 18.5 0.0044 17.3 18.5 8.7 1 1 7 9 9 9 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PVD34998.1 - 0.0052 17.3 18.8 0.0052 17.3 18.8 10.8 1 1 7 9 9 9 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PVD34998.1 - 0.013 15.7 23.0 0.013 15.7 23.0 10.7 2 2 8 10 10 10 0 TATA element modulatory factor 1 TATA binding TNFR_c6 PF00020.18 PVD34999.1 - 1.6e-74 246.0 164.7 5.5e-10 39.5 8.4 11.5 10 1 1 11 11 11 11 TNFR/NGFR cysteine-rich region TMEM132D_C PF15706.5 PVD34999.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ephrin_rec_like PF07699.13 PVD34999.1 - 0.031 14.0 144.7 0.68 9.7 12.3 12.2 2 1 11 13 13 13 0 Putative ephrin-receptor like NCD3G PF07562.14 PVD34999.1 - 1.6 8.8 125.9 0.18 11.8 3.6 11.9 2 2 12 14 14 14 0 Nine Cysteines Domain of family 3 GPCR Glyco_trans_2_3 PF13632.6 PVD35000.1 - 4e-30 105.2 4.9 8.1e-30 104.2 4.9 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD35000.1 - 3.5e-08 33.6 0.1 4.9e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pentapeptide_4 PF13599.6 PVD35001.1 - 3.6e-15 55.9 9.4 0.016 15.4 0.1 5.7 2 1 3 5 5 5 4 Pentapeptide repeats (9 copies) UFD1 PF03152.14 PVD35001.1 - 0.95 8.9 8.6 20 4.6 0.6 4.4 2 2 1 3 3 3 0 Ubiquitin fusion degradation protein UFD1 GvpD PF07088.11 PVD35001.1 - 5.5 5.5 11.5 2.7 6.5 0.5 3.2 1 1 2 3 3 3 0 GvpD gas vesicle protein TNFR_c6 PF00020.18 PVD35003.1 - 1.7e-61 204.4 122.7 3.2e-10 40.2 7.9 9.4 7 1 2 9 9 9 9 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 PVD35003.1 - 0.0024 17.6 112.7 0.72 9.7 9.2 9.8 1 1 9 10 10 10 7 Putative ephrin-receptor like NCD3G PF07562.14 PVD35003.1 - 0.0042 17.0 97.0 0.14 12.2 3.8 9.0 2 2 9 11 11 11 9 Nine Cysteines Domain of family 3 GPCR MG2 PF01835.19 PVD35005.1 - 3.2e-17 62.8 0.2 3e-16 59.6 0.1 2.8 3 0 0 3 3 3 1 MG2 domain MG3 PF17791.1 PVD35005.1 - 6.7e-17 61.5 0.0 3e-16 59.5 0.0 2.2 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD35005.1 - 6.8e-08 32.5 0.9 2.8e-06 27.4 0.1 3.7 3 1 0 3 3 3 1 Macroglobulin domain MG4 A2M_BRD PF07703.14 PVD35005.1 - 3.6e-05 24.2 2.4 0.98 9.8 0.0 3.9 2 2 1 3 3 3 3 Alpha-2-macroglobulin bait region domain CBM_6 PF03422.15 PVD35006.1 - 0.038 14.3 0.1 0.18 12.1 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) PA PF02225.22 PVD35007.1 - 0.00094 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 PA domain RnfC_N PF13375.6 PVD35007.1 - 0.12 12.3 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain LigB PF02900.18 PVD35008.1 - 0.083 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase SGS PF05002.15 PVD35009.1 - 1.1e-35 121.6 3.3 2.5e-35 120.4 3.3 1.7 1 0 0 1 1 1 1 SGS domain TPR_1 PF00515.28 PVD35009.1 - 4e-16 58.1 9.0 2.4e-07 30.3 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35009.1 - 9.9e-15 53.4 7.1 6.2e-06 25.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35009.1 - 2.5e-11 42.8 4.0 0.00038 20.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 PVD35009.1 - 2.1e-10 41.5 2.8 8.3e-10 39.5 2.1 2.4 2 1 0 2 2 2 1 CS domain TPR_19 PF14559.6 PVD35009.1 - 3.1e-09 37.2 0.9 5.5e-07 30.0 1.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35009.1 - 9.6e-09 34.8 4.1 0.0015 18.2 0.1 3.4 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.6 PVD35009.1 - 1.3e-08 34.2 1.6 0.3 11.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD35009.1 - 2.3e-07 30.9 4.7 4.5e-07 30.0 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD35009.1 - 1.1e-06 29.2 4.7 0.00095 19.8 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35009.1 - 1.3e-06 28.4 4.5 0.0007 19.8 0.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35009.1 - 1.7e-06 28.2 1.7 0.00015 22.0 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD35009.1 - 0.00017 21.4 0.9 0.0082 16.0 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35009.1 - 0.00088 19.9 0.2 5.2 8.2 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD35009.1 - 0.00088 19.3 3.9 0.017 15.1 0.2 2.6 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_6 PF13174.6 PVD35009.1 - 0.0054 17.3 4.2 2 9.2 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD35009.1 - 0.019 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 PVD35009.1 - 0.02 14.9 3.0 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TipAS PF07739.13 PVD35009.1 - 0.027 15.0 4.3 1.9 9.1 1.2 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain SHNi-TPR PF10516.9 PVD35009.1 - 0.053 13.0 1.5 5 6.7 0.1 3.1 3 0 0 3 3 3 0 SHNi-TPR DUF3856 PF12968.7 PVD35009.1 - 0.13 12.3 1.6 3.3 7.8 0.1 3.2 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 PVD35009.1 - 0.54 10.4 5.9 3.6 7.7 1.8 3.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 PVD35009.1 - 1.2 9.6 4.0 0.83 10.1 1.0 2.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation zf-B_box PF00643.24 PVD35010.1 - 2.9e-09 36.9 4.4 2.9e-09 36.9 4.4 2.9 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD35010.1 - 1.5e-07 31.3 4.9 1.5e-07 31.3 4.9 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD35010.1 - 5e-06 26.3 5.3 5e-06 26.3 5.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD35010.1 - 1e-05 25.3 6.1 1e-05 25.3 6.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD35010.1 - 7e-05 23.1 9.1 7e-05 23.1 9.1 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD35010.1 - 0.0013 18.5 3.1 0.0013 18.5 3.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PVD35010.1 - 0.0067 16.1 2.7 0.023 14.4 2.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger CEBP_ZZ PF16366.5 PVD35010.1 - 0.013 15.7 9.0 0.31 11.3 0.9 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SEA PF01390.20 PVD35010.1 - 0.022 14.9 0.2 0.094 12.8 0.2 2.1 1 0 0 1 1 1 0 SEA domain zf-C3HC4_4 PF15227.6 PVD35010.1 - 0.14 12.3 14.8 0.077 13.2 7.3 3.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 PVD35010.1 - 0.28 11.3 7.1 4.5 7.5 0.2 2.8 3 0 0 3 3 3 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 PVD35010.1 - 0.43 10.4 14.4 0.036 13.9 4.8 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PVD35010.1 - 0.6 10.0 20.8 0.031 14.1 9.6 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 PVD35010.1 - 5.4 7.2 17.3 7e+03 -2.8 17.3 2.7 1 1 0 1 1 1 0 FYVE zinc finger RRM_1 PF00076.22 PVD35011.1 - 8.2e-17 60.8 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD35011.1 - 0.069 13.3 0.0 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif GREB1 PF15782.5 PVD35011.1 - 5.6 3.9 11.4 7.6 3.5 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mito_carr PF00153.27 PVD35012.1 - 3.3e-61 203.2 5.0 3.9e-21 74.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SOCS_box PF07525.16 PVD35013.1 - 1e-07 32.2 2.9 2.6e-07 30.9 2.9 1.7 1 0 0 1 1 1 1 SOCS box CH PF00307.31 PVD35014.1 - 6.4e-09 36.0 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD35014.1 - 7.6e-07 28.9 0.1 2.3e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 PVD35014.1 - 0.0053 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PDZ PF00595.24 PVD35016.1 - 1.2e-11 44.7 1.4 3.3e-11 43.4 1.4 1.7 1 0 0 1 1 1 1 PDZ domain DUF4757 PF15949.5 PVD35016.1 - 2.6e-08 34.5 10.4 2.6e-08 34.5 10.4 7.0 8 1 0 8 8 8 1 Domain of unknown function (DUF4757) LIM PF00412.22 PVD35016.1 - 8.4e-08 32.3 4.2 1.6e-07 31.4 4.2 1.5 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 PVD35016.1 - 9e-06 25.4 0.3 2.8e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD35016.1 - 0.021 15.2 0.2 0.069 13.5 0.2 1.9 1 0 0 1 1 1 0 PDZ domain Amidase_6 PF12671.7 PVD35018.1 - 0.052 13.7 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Putative amidase domain Stanniocalcin PF03298.13 PVD35018.1 - 0.053 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Stanniocalcin family zf-BED PF02892.15 PVD35019.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.8 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 PVD35019.1 - 0.04 14.4 0.5 0.04 14.4 0.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Amidase_6 PF12671.7 PVD35019.1 - 0.058 13.5 4.6 0.32 11.1 0.6 2.6 2 0 0 2 2 2 0 Putative amidase domain AAA_23 PF13476.6 PVD35020.1 - 3e-28 99.7 0.0 3e-28 99.7 0.0 8.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 PVD35020.1 - 6.9e-10 39.2 8.2 0.00038 20.3 0.0 4.2 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 PVD35020.1 - 1.7e-07 31.0 2.9 1.7e-07 31.0 2.9 5.2 4 0 0 4 4 4 1 Rad50 zinc hook motif SMC_N PF02463.19 PVD35020.1 - 1.3e-05 24.8 36.0 0.00011 21.7 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 PVD35020.1 - 1.5e-05 25.2 0.0 5.1e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 PVD35020.1 - 0.0022 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD35020.1 - 0.017 15.5 0.0 0.017 15.5 0.0 4.5 5 2 0 5 5 5 0 AAA ATPase domain AAA_13 PF13166.6 PVD35020.1 - 0.017 13.8 0.0 0.017 13.8 0.0 7.0 4 2 1 6 6 6 0 AAA domain ABC_tran PF00005.27 PVD35020.1 - 0.025 15.1 0.0 0.025 15.1 0.0 7.6 3 2 0 3 3 3 0 ABC transporter LRR_8 PF13855.6 PVD35021.1 - 4.2e-40 135.3 44.1 4.9e-14 51.8 4.1 8.8 8 1 1 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 PVD35021.1 - 2.6e-20 72.1 45.8 0.00015 22.1 1.8 11.6 6 3 7 14 14 14 6 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD35021.1 - 4.5e-12 46.1 0.0 2.3e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD35021.1 - 9.3e-12 45.6 0.0 2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD35021.1 - 3.7e-09 36.6 9.4 0.0051 16.8 0.2 4.0 4 0 0 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD35021.1 - 4.4e-07 29.6 10.1 0.009 15.5 0.7 5.0 4 1 2 6 6 6 3 Leucine-rich repeat LRRNT PF01462.18 PVD35021.1 - 0.00025 20.6 1.5 0.00062 19.4 0.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain DUF1863 PF08937.11 PVD35021.1 - 0.0031 17.8 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_8 PF13855.6 PVD35022.1 - 7.5e-33 112.1 55.5 5.9e-13 48.4 10.1 9.2 8 2 2 10 10 10 5 Leucine rich repeat LRR_4 PF12799.7 PVD35022.1 - 1.7e-17 63.2 45.2 7.1e-05 23.1 6.0 9.7 5 2 5 10 10 10 7 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD35022.1 - 3.6e-12 46.4 0.1 1.4e-11 44.5 0.1 1.9 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD35022.1 - 1.3e-11 45.1 0.0 3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD35022.1 - 6.1e-10 39.1 13.8 0.00028 20.9 0.3 4.3 5 1 0 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 PVD35022.1 - 6.8e-05 22.4 0.9 6.8e-05 22.4 0.9 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 PVD35022.1 - 0.00065 19.2 7.6 0.048 13.2 0.3 4.1 4 0 0 4 4 4 2 Leucine-rich repeat DUF1863 PF08937.11 PVD35022.1 - 0.0013 19.1 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 PVD35022.1 - 0.24 11.5 25.9 7.3 6.9 0.4 9.7 14 0 0 14 14 13 0 Leucine Rich repeat LRR_2 PF07723.13 PVD35022.1 - 0.26 12.0 1.5 2.6 8.8 0.3 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat Toxin_11 PF07473.11 PVD35022.1 - 0.42 10.7 3.2 1.1 9.4 3.2 1.7 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Cyclin_N PF00134.23 PVD35023.1 - 5.3e-48 161.9 2.0 8e-47 158.1 0.3 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Spt20 PF12090.8 PVD35023.1 - 5.1e-29 101.6 0.1 2.1e-18 66.8 0.0 4.7 4 2 1 5 5 5 2 Spt20 family Cyclin_C PF02984.19 PVD35023.1 - 4.6e-26 91.2 0.3 1.6e-25 89.5 0.3 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 PVD35023.1 - 1.5e-08 35.5 2.3 4.6e-08 33.9 2.3 1.9 1 0 0 1 1 1 1 N-terminal region of cyclin_N Raftlin PF15250.6 PVD35024.1 - 4.3e-10 39.0 0.0 5.6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Raftlin DUF4177 PF13783.6 PVD35024.1 - 1.4e-05 25.3 0.0 0.43 10.9 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4177) SOAR PF16533.5 PVD35025.1 - 1.4e-37 127.7 1.2 1.4e-37 127.7 1.2 3.1 3 0 0 3 3 3 1 STIM1 Orai1-activating region SAM_1 PF00536.30 PVD35025.1 - 2.6e-09 37.4 0.0 6.8e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD35025.1 - 3.5e-08 33.4 0.1 3.8e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) YfdX PF10938.8 PVD35025.1 - 0.96 9.4 3.9 6.1 6.8 3.9 2.2 1 1 0 1 1 1 0 YfdX protein SRA1 PF07304.11 PVD35027.1 - 1.7e-24 86.3 0.5 2.5e-24 85.7 0.5 1.2 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) UDPG_MGDP_dh_N PF03721.14 PVD35028.1 - 2.2e-64 216.5 0.1 3.5e-64 215.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PVD35028.1 - 2e-37 127.8 0.1 1.6e-36 124.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 PVD35028.1 - 5.3e-23 81.1 0.0 1.3e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 PVD35028.1 - 0.013 15.7 0.0 0.056 13.6 0.0 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Y_phosphatase PF00102.27 PVD35028.1 - 0.051 13.1 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sacchrp_dh_NADP PF03435.18 PVD35028.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain W2 PF02020.18 PVD35029.1 - 1.4e-20 73.1 2.8 1.4e-20 73.1 2.8 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 PVD35029.1 - 1.5e-09 37.2 16.1 8.9e-05 22.1 4.0 4.3 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 PVD35029.1 - 2.3e-05 22.8 4.3 0.00016 20.0 4.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PVD35029.1 - 0.00093 18.2 1.6 0.0018 17.3 1.6 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 PVD35029.1 - 0.018 14.8 15.0 0.22 11.3 9.3 3.7 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 PVD35029.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Myelin_PLP PF01275.19 PVD35030.1 - 1.4e-18 67.7 3.3 2.2e-18 67.0 3.3 1.2 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Mid2 PF04478.12 PVD35030.1 - 0.039 13.8 0.1 0.039 13.8 0.1 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2107 PF09880.9 PVD35030.1 - 0.055 13.6 2.3 0.13 12.4 2.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) UL45 PF05473.12 PVD35030.1 - 6.3 6.4 9.1 0.57 9.8 2.2 2.0 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like HMMR_N PF15905.5 PVD35032.1 - 1.9e-13 50.6 52.4 1.9e-13 50.6 52.4 3.5 2 1 1 3 3 3 1 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 PVD35032.1 - 0.0027 18.2 20.3 0.0027 18.2 20.3 7.3 2 2 4 6 6 6 1 Apg6 coiled-coil region HTH_34 PF13601.6 PVD35032.1 - 0.3 11.3 5.1 1 9.6 0.5 3.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain TED_complement PF07678.14 PVD35033.1 - 5.7e-41 140.6 0.0 8e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 PVD35033.1 - 1e-12 48.5 0.1 3.3e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain SQHop_cyclase_C PF13243.6 PVD35033.1 - 1.8e-05 24.0 0.0 7.6e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 PVD35033.1 - 0.00047 19.8 0.0 0.024 14.4 0.0 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat A2M PF00207.22 PVD35033.1 - 0.0012 18.6 0.1 0.003 17.4 0.1 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Glu_dehyd_C PF16912.5 PVD35033.1 - 0.089 12.3 0.2 0.83 9.1 0.0 2.4 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus A2M_BRD PF07703.14 PVD35034.1 - 3.2e-28 98.8 4.1 1.6e-26 93.3 0.4 3.0 2 1 1 3 3 3 3 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD35034.1 - 4.8e-16 58.8 0.0 2.8e-15 56.3 0.0 2.4 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD35034.1 - 1.5e-15 57.4 0.4 2.3e-14 53.6 0.1 2.9 2 0 0 2 2 2 1 MG2 domain MG4 PF17789.1 PVD35034.1 - 2.2e-06 27.7 6.0 5.6e-06 26.4 0.2 4.1 4 1 0 4 4 4 1 Macroglobulin domain MG4 OMP_b-brl_2 PF13568.6 PVD35034.1 - 0.032 14.2 0.1 0.14 12.1 0.1 2.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Melibiase_2 PF16499.5 PVD35035.1 - 4.1e-263 869.5 20.1 4.1e-136 452.7 3.7 3.1 3 0 0 3 3 3 3 Alpha galactosidase A Melibiase_2_C PF17450.2 PVD35035.1 - 5.7e-12 45.7 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 PVD35035.1 - 3.7e-11 42.6 0.0 4.7e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Melibiase Melibiase_C PF17801.1 PVD35035.1 - 2.3e-07 30.8 0.0 5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Toprim_3 PF13362.6 PVD35035.1 - 0.0018 18.6 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 2 Toprim domain 2Fe-2S_thioredx PF01257.19 PVD35035.1 - 0.0062 16.4 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like [2Fe-2S] ferredoxin Melibiase_2 PF16499.5 PVD35036.1 - 9e-142 471.3 6.2 1.1e-141 471.0 6.2 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 PVD35036.1 - 1.3e-14 54.2 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 PVD35036.1 - 4.6e-11 42.6 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PVD35036.1 - 3.8e-05 22.8 0.0 6.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 PVD35037.1 - 2.8e-115 384.4 2.8 4.9e-115 383.6 2.8 1.4 1 0 0 1 1 1 1 Alpha galactosidase A TAFII55_N PF04658.13 PVD35037.1 - 7.2e-60 201.3 0.8 1.3e-59 200.5 0.8 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Melibiase_2_C PF17450.2 PVD35037.1 - 9.6e-08 32.2 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 PVD35037.1 - 5.9e-06 26.3 0.0 5.9e-06 26.3 0.0 1.9 2 0 0 2 2 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PVD35037.1 - 8.6e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Melibiase APG6_N PF17675.1 PVD35037.1 - 0.019 15.5 7.9 0.041 14.4 7.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Glyco_hydro_97 PF10566.9 PVD35037.1 - 0.022 14.1 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 RNase_J_C PF17770.1 PVD35037.1 - 1 10.5 3.6 1.8 9.7 1.9 2.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF4446 PF14584.6 PVD35037.1 - 1.2 9.1 4.4 11 6.0 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF1451 PF07295.11 PVD35037.1 - 2.4 8.2 8.3 5.2 7.1 8.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain YabA PF06156.13 PVD35037.1 - 7.4 7.3 7.2 18 6.0 7.2 1.6 1 0 0 1 1 1 0 Initiation control protein YabA 3Beta_HSD PF01073.19 PVD35038.1 - 9e-70 234.8 0.0 1.1e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PVD35038.1 - 9.2e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD35038.1 - 8.3e-19 68.1 0.0 1.5e-17 64.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PVD35038.1 - 1.8e-14 53.5 0.0 8.2e-11 41.6 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 PVD35038.1 - 2.2e-14 53.8 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PVD35038.1 - 5.2e-10 38.9 0.0 7.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PVD35038.1 - 6.3e-09 35.4 0.0 1.3e-06 27.8 0.0 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 PVD35038.1 - 3.7e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 PVD35038.1 - 0.00053 19.9 0.3 0.049 13.5 0.1 2.3 1 1 1 2 2 2 1 KR domain TrkA_N PF02254.18 PVD35038.1 - 0.0027 17.9 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 PVD35038.1 - 0.02 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 PVD35038.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase EF-hand_1 PF00036.32 PVD35039.1 - 8.4e-33 109.5 16.4 5.2e-09 35.0 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD35039.1 - 1.6e-28 98.9 9.0 5.1e-14 52.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD35039.1 - 2.6e-25 86.1 11.0 4.9e-09 35.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PVD35039.1 - 1.4e-23 82.5 12.8 8.4e-13 48.0 0.6 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PVD35039.1 - 4.9e-16 58.8 0.2 4.9e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD35039.1 - 4e-12 45.0 16.8 8.1e-06 25.1 0.2 4.5 4 1 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 PVD35039.1 - 2.4e-06 27.5 6.0 0.022 14.7 0.7 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 PVD35039.1 - 0.00038 20.8 1.8 0.37 11.1 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 PVD35039.1 - 0.00086 19.1 3.0 0.033 14.0 2.6 2.1 1 1 1 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 PVD35039.1 - 0.0013 19.0 1.1 0.38 11.1 0.3 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Sigma54_CBD PF04963.13 PVD35039.1 - 0.0049 16.7 0.5 0.0066 16.3 0.5 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 PVD35039.1 - 0.0054 16.9 0.6 0.48 10.7 0.1 2.6 2 1 1 3 3 3 1 Dockerin type I domain SurA_N_2 PF13623.6 PVD35039.1 - 0.0057 16.5 2.8 1.1 9.1 0.8 2.8 1 1 1 2 2 2 2 SurA N-terminal domain DUF3349 PF11829.8 PVD35039.1 - 0.0069 17.1 2.8 5.5 7.8 0.1 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 PVD35039.1 - 0.0077 16.2 2.3 0.075 13.0 0.1 2.5 1 1 2 3 3 3 1 Tellurite resistance protein TerB DUF853 PF05872.12 PVD35039.1 - 0.022 13.4 0.7 0.19 10.3 0.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 PVD35039.1 - 0.024 15.5 0.3 7.1 7.6 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain FlgD PF03963.14 PVD35039.1 - 0.064 13.6 0.2 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region SUB1_ProdP9 PF18213.1 PVD35039.1 - 0.067 13.0 0.9 0.14 12.0 0.2 1.8 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 UPF0154 PF03672.13 PVD35039.1 - 0.085 12.9 0.2 3.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SRI PF08236.11 PVD35039.1 - 0.085 13.0 4.0 1.1 9.5 0.3 3.1 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Caleosin PF05042.13 PVD35039.1 - 0.1 12.5 1.3 7.8 6.4 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein Leucyl-specific PF14795.6 PVD35039.1 - 0.14 12.3 1.4 9.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF21 PF01595.20 PVD35039.1 - 0.14 11.8 0.5 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SHOCT PF09851.9 PVD35039.1 - 0.37 10.6 0.2 0.37 10.6 0.2 3.4 3 1 0 3 3 3 0 Short C-terminal domain DUF3008 PF11450.8 PVD35039.1 - 4.7 7.4 5.4 2.5 8.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) CLN5 PF15014.6 PVD35040.1 - 1.4e-120 402.6 7.4 1.5e-120 402.4 7.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ShlB PF03865.13 PVD35040.1 - 0.0099 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB COMM_domain PF07258.14 PVD35041.1 - 3.5e-15 55.9 0.3 4.1e-15 55.7 0.3 1.1 1 0 0 1 1 1 1 COMM domain mRNA_triPase PF02940.15 PVD35041.1 - 0.057 13.1 0.0 0.061 13.0 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain zf-B_box PF00643.24 PVD35042.1 - 5.3e-12 45.7 43.3 5.1e-09 36.2 9.6 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD35042.1 - 3.1e-07 30.2 9.0 3.1e-07 30.2 9.0 3.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD35042.1 - 8.6e-07 28.7 10.6 8.6e-07 28.7 10.6 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD35042.1 - 6.1e-06 26.5 9.7 6.1e-06 26.5 9.7 3.9 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 PVD35042.1 - 5.1e-05 23.1 7.6 5.1e-05 23.1 7.6 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD35042.1 - 6.5e-05 22.8 8.3 6.5e-05 22.8 8.3 4.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD35042.1 - 7.6e-05 22.7 7.5 7.6e-05 22.7 7.5 3.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD35042.1 - 0.0032 17.3 9.7 0.0032 17.3 9.7 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF677 PF05055.12 PVD35042.1 - 0.012 14.6 0.3 0.02 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) zf-C3HC4_4 PF15227.6 PVD35042.1 - 0.017 15.3 8.6 0.017 15.3 8.6 3.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Mating_N PF12731.7 PVD35043.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 Meis_PKNOX_N PF16493.5 PVD35043.1 - 0.08 13.3 0.2 0.12 12.8 0.2 1.4 1 1 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 LisH_2 PF16045.5 PVD35044.1 - 4.6e-12 44.7 0.0 8e-12 44.0 0.0 1.4 1 0 0 1 1 1 1 LisH SH3_1 PF00018.28 PVD35045.1 - 6.5e-49 163.3 0.7 5.2e-13 48.4 0.0 4.2 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 PVD35045.1 - 1.4e-42 143.3 0.4 6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 PVD35045.1 - 2.1e-37 126.6 0.2 3.9e-08 32.8 0.0 4.1 4 0 0 4 4 4 4 Variant SH3 domain DUF5348 PF17295.2 PVD35045.1 - 0.00098 19.0 2.7 4.7 7.2 0.0 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF5348) TrkA_C PF02080.21 PVD35045.1 - 0.028 14.2 0.2 40 4.1 0.0 3.2 3 0 0 3 3 3 0 TrkA-C domain DUF5599 PF18141.1 PVD35045.1 - 0.046 13.9 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5599) SNAP PF14938.6 PVD35046.1 - 0.042 13.3 0.2 0.059 12.8 0.2 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP RCC1 PF00415.18 PVD35047.1 - 2.7e-217 703.5 78.3 2.8e-14 53.5 0.5 19.6 20 0 0 20 20 20 18 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD35047.1 - 4.3e-74 243.1 120.9 4.9e-08 32.6 1.8 20.3 22 0 0 22 22 22 15 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 PVD35047.1 - 1e-57 196.0 0.0 2e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.8 PVD35047.1 - 1.3e-32 111.9 3.8 1.5e-32 111.7 1.4 2.3 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.13 PVD35047.1 - 1.7e-21 76.3 5.5 1.7e-21 76.3 5.5 4.3 6 0 0 6 6 6 1 Mib_herc2 Cyt-b5 PF00173.28 PVD35047.1 - 2.7e-20 72.3 0.2 4.3e-19 68.4 0.2 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 PVD35047.1 - 3.1e-12 46.1 7.9 7.7e-12 44.8 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type ANAPC10 PF03256.16 PVD35047.1 - 3.8e-09 36.5 0.2 2.2e-08 33.9 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) SH3_15 PF18346.1 PVD35047.1 - 2.8e-07 30.8 5.8 2.2e-05 24.7 0.5 3.7 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ubie_methyltran PF01209.18 PVD35047.1 - 0.54 9.6 2.2 16 4.7 0.0 3.8 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family Myb_DNA-bind_7 PF15963.5 PVD35048.1 - 0.0016 18.3 0.3 0.0051 16.7 0.3 1.9 1 0 0 1 1 1 1 Myb DNA-binding like JUPITER PF17054.5 PVD35049.1 - 5.7e-06 26.0 3.9 5.7e-06 26.0 3.9 2.0 2 1 0 2 2 2 1 Microtubule-Associated protein Jupiter Beta-lactamase PF00144.24 PVD35050.1 - 2.2e-15 56.8 0.0 3.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35051.1 - 0.0026 17.1 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Vezatin PF12632.7 PVD35051.1 - 0.21 11.0 0.0 0.22 10.9 0.0 1.0 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Beta-lactamase PF00144.24 PVD35052.1 - 2.7e-23 82.8 0.1 4.1e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35053.1 - 4.9e-48 164.1 0.5 1.1e-47 162.9 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 PVD35053.1 - 0.0094 16.4 2.5 2.9 8.4 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3471) Beta-lactamase PF00144.24 PVD35054.1 - 6e-39 134.2 2.1 1.6e-23 83.5 0.5 2.2 1 1 1 2 2 2 2 Beta-lactamase Beta-lactamase PF00144.24 PVD35055.1 - 1e-35 123.6 0.0 1.2e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35056.1 - 1.9e-54 185.2 0.7 5.5e-49 167.2 0.2 2.2 2 0 0 2 2 2 2 Beta-lactamase Beta-lactamase PF00144.24 PVD35057.1 - 7.4e-49 166.8 0.1 1.1e-48 166.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35058.1 - 6.6e-26 91.3 0.2 1e-25 90.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35059.1 - 1e-44 153.1 0.0 1.4e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase PRIMA1 PF16101.5 PVD35061.1 - 0.35 10.9 8.8 0.28 11.2 1.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Beta-lactamase PF00144.24 PVD35062.1 - 1.3e-34 119.9 0.4 1.8e-34 119.5 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase TMF_TATA_bd PF12325.8 PVD35063.1 - 0.0025 18.0 5.0 0.0039 17.4 5.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 PVD35063.1 - 0.0032 18.0 3.1 0.0032 18.0 3.1 2.2 2 0 0 2 2 2 1 SlyX DUF4795 PF16043.5 PVD35063.1 - 0.0051 16.4 2.3 0.0088 15.7 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF3160 PF11369.8 PVD35063.1 - 0.0098 14.4 0.8 0.012 14.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3160) ADIP PF11559.8 PVD35063.1 - 0.01 15.9 5.0 0.01 15.9 5.0 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 PVD35063.1 - 0.011 15.8 2.3 0.011 15.8 2.3 1.7 2 0 0 2 2 1 0 TolA binding protein trimerisation Alanine_zipper PF11839.8 PVD35063.1 - 0.017 15.5 7.5 0.03 14.7 7.5 1.5 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Tropomyosin_1 PF12718.7 PVD35063.1 - 0.019 15.1 8.2 0.027 14.6 8.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 PVD35063.1 - 0.023 14.5 2.2 0.023 14.5 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 PVD35063.1 - 0.033 14.6 0.6 0.033 14.6 0.6 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.6 PVD35063.1 - 0.035 14.5 1.7 0.035 14.5 1.7 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF730 PF05325.11 PVD35063.1 - 0.06 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) V_ATPase_I PF01496.19 PVD35063.1 - 0.061 11.2 1.5 0.058 11.3 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 PVD35063.1 - 0.072 13.6 7.7 0.17 12.4 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1192 PF06698.11 PVD35063.1 - 0.092 12.8 1.4 0.32 11.1 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Dynein_C PF18199.1 PVD35063.1 - 0.12 11.6 3.2 0.13 11.5 2.3 1.4 1 1 0 1 1 1 0 Dynein heavy chain C-terminal domain DUF3138 PF11336.8 PVD35063.1 - 0.14 10.8 0.4 0.17 10.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4407 PF14362.6 PVD35063.1 - 0.2 11.0 3.9 0.26 10.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 PVD35063.1 - 0.35 11.1 2.6 0.4 11.0 1.5 1.6 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 PVD35063.1 - 0.42 10.4 7.6 0.18 11.6 4.1 2.2 2 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 PVD35063.1 - 0.53 10.8 9.4 0.082 13.4 4.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB TRAF_BIRC3_bd PF16673.5 PVD35063.1 - 0.69 9.7 8.8 0.051 13.4 3.3 2.0 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain YabA PF06156.13 PVD35063.1 - 0.81 10.4 6.0 1.2 9.8 5.6 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Spc24 PF08286.11 PVD35063.1 - 2.1 8.6 7.8 6.5 7.0 7.9 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Beta-lactamase PF00144.24 PVD35064.1 - 1.1e-11 44.5 0.1 5.6e-07 29.1 0.0 2.1 1 1 0 2 2 2 2 Beta-lactamase Beta-lactamase PF00144.24 PVD35065.1 - 1.5e-28 100.0 0.3 2.4e-28 99.4 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 PVD35066.1 - 1.8e-44 152.3 0.0 2.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Trans_reg_C PF00486.28 PVD35066.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Ank_2 PF12796.7 PVD35067.1 - 8.9e-18 64.7 2.8 2.4e-07 31.3 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD35067.1 - 4.3e-13 48.2 2.6 0.0031 17.9 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PVD35067.1 - 5.9e-12 45.5 5.8 1.3e-05 25.4 0.6 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PVD35067.1 - 4.5e-11 43.0 0.5 1.3e-06 28.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35067.1 - 7e-08 32.6 5.2 0.0013 19.0 1.9 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Dscam_C PF12355.8 PVD35067.1 - 0.076 14.0 0.7 0.25 12.3 0.1 1.9 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal RED_N PF07808.13 PVD35068.1 - 1.6e-94 315.9 16.6 1.6e-94 315.9 16.6 3.3 2 1 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 PVD35068.1 - 1.3e-54 183.4 4.8 1.3e-54 183.4 4.8 3.8 4 0 0 4 4 4 1 RED-like protein C-terminal region Lsm_interact PF05391.11 PVD35068.1 - 0.00041 19.7 0.5 0.0017 17.7 0.5 2.2 1 0 0 1 1 1 1 Lsm interaction motif zf-C2H2_4 PF13894.6 PVD35069.1 - 0.034 15.0 8.5 2.2 9.3 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD35069.1 - 0.1 13.1 9.3 4.2 8.0 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-B_box PF00643.24 PVD35069.1 - 1.5 9.0 6.0 0.84 9.9 2.4 2.4 2 0 0 2 2 2 0 B-box zinc finger Alpha-amylase PF00128.24 PVD35070.1 - 1.7e-78 264.5 0.0 2.3e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain zf-RING_UBOX PF13445.6 PVD35071.1 - 5e-05 23.2 7.2 0.00019 21.4 7.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD35071.1 - 0.00015 21.6 10.3 0.00015 21.6 10.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD35071.1 - 0.00022 21.0 14.1 0.00039 20.2 12.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD35071.1 - 0.00024 20.9 11.1 0.00024 20.9 11.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 PVD35071.1 - 0.00044 20.1 3.8 1 9.5 0.4 4.0 4 0 0 4 4 4 2 NHL repeat Prok-RING_4 PF14447.6 PVD35071.1 - 0.00066 19.5 8.9 0.00066 19.5 8.9 2.9 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD35071.1 - 0.0035 17.6 12.0 0.0035 17.6 12.0 3.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD35071.1 - 0.034 14.3 2.5 0.034 14.3 2.5 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Coatomer_WDAD PF04053.14 PVD35071.1 - 0.067 12.2 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region zf-C3HC4_2 PF13923.6 PVD35071.1 - 1.6 8.6 15.5 0.068 13.0 5.9 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD35071.1 - 5.3 7.4 12.5 1 9.7 6.6 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain Pkinase_Tyr PF07714.17 PVD35072.1 - 1.4e-36 126.1 0.0 2.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35072.1 - 7.1e-23 81.3 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 PVD35072.1 - 1.2e-21 76.4 14.6 1.8e-11 44.0 1.7 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD35072.1 - 5.2e-21 74.7 6.6 4.7e-11 43.0 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD35072.1 - 2.3e-20 72.1 6.7 3.2e-06 27.3 0.9 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 PVD35072.1 - 4.8e-19 68.7 2.4 9.5e-12 45.3 0.7 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD35072.1 - 1.2e-15 56.0 5.1 0.00051 20.3 0.1 4.4 5 0 0 5 5 5 3 Ankyrin repeat Helicase_C_2 PF13307.6 PVD35073.1 - 3.1e-53 180.5 0.0 7.4e-53 179.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PVD35073.1 - 1.1e-38 132.6 0.1 2.5e-38 131.5 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 Sel1 PF08238.12 PVD35074.1 - 2.2e-29 101.2 24.3 4.1e-06 27.3 0.5 6.6 6 0 0 6 6 6 5 Sel1 repeat TPR_7 PF13176.6 PVD35074.1 - 0.00037 20.3 6.4 2.6 8.3 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Duffy_binding PF05424.11 PVD35074.1 - 0.041 13.9 0.9 0.42 10.6 0.2 2.4 2 0 0 2 2 2 0 Duffy binding domain TPR_1 PF00515.28 PVD35074.1 - 0.65 9.9 18.6 15 5.6 0.2 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35074.1 - 0.83 10.4 0.0 0.83 10.4 0.0 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 PVD35074.1 - 0.86 9.3 7.7 1.1 9.0 0.3 3.8 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 ELMO_CED12 PF04727.13 PVD35075.1 - 5.3e-42 143.9 0.9 7.5e-42 143.4 0.9 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family APC_N_CC PF16689.5 PVD35075.1 - 0.06 13.4 1.0 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain TMEM131_like PF12371.8 PVD35076.1 - 1.1e-22 80.1 4.8 1.6e-18 66.7 0.1 6.8 9 0 0 9 9 9 1 Transmembrane protein 131-like SH3_1 PF00018.28 PVD35076.1 - 2.3e-22 78.3 0.2 2.2e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PVD35076.1 - 2.9e-22 78.3 0.3 4.8e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 PVD35076.1 - 8e-16 58.1 2.2 2e-15 56.8 1.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 PVD35076.1 - 4.5e-15 55.1 0.0 1.1e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain ASH PF15780.5 PVD35076.1 - 1e-11 44.9 3.2 1.2 9.4 0.0 7.7 8 0 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SH3_3 PF08239.11 PVD35076.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Fasciclin PF02469.22 PVD35077.1 - 2.3e-103 341.4 2.2 7e-28 97.4 0.1 4.1 4 0 0 4 4 4 4 Fasciclin domain DUF1967 PF09269.11 PVD35077.1 - 0.14 12.1 0.0 32 4.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Ribosomal_L6 PF00347.23 PVD35078.1 - 7.3e-29 100.3 6.0 1.5e-14 54.4 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Yip1 PF04893.17 PVD35079.1 - 5.2e-05 23.0 8.4 8.1e-05 22.4 8.4 1.4 1 0 0 1 1 1 1 Yip1 domain Promethin PF16015.5 PVD35080.1 - 0.031 14.2 4.6 0.031 14.2 4.6 2.3 1 1 1 2 2 2 0 Promethin 7TM_GPCR_Srx PF10328.9 PVD35080.1 - 0.05 13.2 3.5 0.076 12.6 3.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3671 PF12420.8 PVD35080.1 - 0.091 12.8 0.9 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function 7TM_GPCR_Srt PF10321.9 PVD35080.1 - 0.12 11.3 5.2 0.15 11.0 5.2 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF4181 PF13789.6 PVD35080.1 - 0.8 10.0 5.2 0.39 11.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Yip1 PF04893.17 PVD35081.1 - 3.5e-16 59.4 3.6 4.6e-16 59.0 3.6 1.1 1 0 0 1 1 1 1 Yip1 domain DUF4834 PF16118.5 PVD35081.1 - 0.23 12.4 0.0 0.47 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ERK-JNK_inhib PF15002.6 PVD35082.1 - 4.2e-50 170.2 0.0 4.6e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Otopetrin PF03189.13 PVD35083.1 - 2e-89 300.5 30.7 3.4e-65 220.6 11.1 2.7 2 1 1 3 3 3 2 Otopetrin zf-C2H2 PF00096.26 PVD35087.1 - 3.5e-05 24.0 8.9 0.0012 19.2 4.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD35087.1 - 0.00039 20.7 4.1 0.00048 20.4 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger double domain Glyco_transf_54 PF04666.13 PVD35088.1 - 1.7e-120 401.3 0.0 2.3e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4404 PF14357.6 PVD35088.1 - 0.13 12.9 0.1 0.36 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TNF PF00229.18 PVD35089.1 - 3.7e-11 43.1 0.0 1.5e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family CEP44 PF15007.6 PVD35090.1 - 2.7e-39 134.2 0.2 2.7e-39 134.2 0.2 1.8 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 STAT_int PF02865.17 PVD35090.1 - 0.0038 17.7 1.7 0.0084 16.6 1.7 1.5 1 0 0 1 1 1 1 STAT protein, protein interaction domain DUF1664 PF07889.12 PVD35090.1 - 0.26 11.4 2.1 0.3 11.1 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 PVD35091.1 - 5.9e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD35091.1 - 5.4e-05 23.3 0.0 0.73 10.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PVD35091.1 - 0.017 15.7 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TRP_2 PF08344.11 PVD35092.1 - 6.9e-24 83.8 0.0 1.6e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 PVD35092.1 - 2.4e-18 66.3 16.5 4.5e-12 45.7 3.0 2.3 1 1 1 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PVD35092.1 - 1.9e-07 30.1 15.6 0.00056 18.7 0.1 2.4 2 0 0 2 2 2 2 Polycystin cation channel Trigger_C PF05698.14 PVD35093.1 - 0.089 12.8 1.3 0.45 10.5 0.2 2.2 2 1 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DUF1640 PF07798.11 PVD35093.1 - 0.16 12.0 2.0 0.24 11.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Methyltransf_22 PF13383.6 PVD35094.1 - 1.4e-31 110.0 0.3 8.1e-18 64.9 0.1 2.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 PVD35094.1 - 1.2e-13 51.5 0.2 5.6e-06 26.5 0.1 2.5 2 1 0 2 2 2 2 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD35094.1 - 0.00014 22.0 0.2 0.47 10.7 0.0 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Methyltransf_8 PF05148.15 PVD35094.1 - 0.049 13.5 0.1 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase SsgA PF04686.12 PVD35094.1 - 0.072 13.1 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA DUF4460 PF14687.6 PVD35094.1 - 0.074 13.1 0.0 18 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) DUF765 PF05570.11 PVD35094.1 - 0.31 11.2 1.4 30 4.9 0.1 2.5 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Myc-LZ PF02344.15 PVD35094.1 - 4.3 7.5 6.8 18 5.5 0.4 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain Methyltransf_22 PF13383.6 PVD35095.1 - 1e-09 38.3 0.1 5.8e-07 29.3 0.1 2.0 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 PVD35095.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.5 1 1 1 2 2 2 0 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PVD35096.1 - 9.1e-09 35.2 0.0 1e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 PVD35097.1 - 1.4e-22 80.1 2.8 2.6e-08 34.3 0.2 3.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD35097.1 - 1.5e-19 69.5 9.9 9.4e-06 25.9 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 PVD35097.1 - 9e-15 53.3 2.2 0.005 17.2 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PVD35097.1 - 3.3e-14 52.8 1.1 0.00048 20.4 0.0 4.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD35097.1 - 1.1e-13 51.4 2.6 4.7e-05 23.9 0.1 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD35097.1 - 7.2e-09 35.9 0.4 2e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 SOCS box Mito_fiss_reg PF05308.11 PVD35099.1 - 0.0025 17.9 3.3 0.0032 17.6 3.3 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator SMN PF06003.12 PVD35099.1 - 5.6 6.1 10.1 7.7 5.7 10.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pantoate_transf PF02548.15 PVD35100.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Methyltransf_21 PF05050.12 PVD35101.1 - 0.0012 18.9 0.0 0.0015 18.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PVD35101.1 - 0.0081 15.8 0.0 0.0086 15.7 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_22 PF13383.6 PVD35102.1 - 1.4e-17 64.2 0.1 1.7e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD35102.1 - 1e-05 25.6 0.1 1.2e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD35102.1 - 0.053 13.8 0.1 0.074 13.3 0.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Methyltransf_22 PF13383.6 PVD35103.1 - 4.9e-18 65.6 0.0 6.4e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD35103.1 - 6.4e-06 26.3 0.0 8e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMF_TATA_bd PF12325.8 PVD35103.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GRDP-like PF07173.12 PVD35104.1 - 3e-44 151.1 3.9 1.7e-37 129.2 0.3 3.2 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like FAS_I_H PF18314.1 PVD35104.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain GRDP-like PF07173.12 PVD35105.1 - 3.4e-45 154.2 3.9 9e-39 133.4 0.4 3.2 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like FAS_I_H PF18314.1 PVD35105.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain TRP_2 PF08344.11 PVD35106.1 - 8.1e-24 83.6 0.6 1.7e-23 82.6 0.6 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 PVD35106.1 - 8.9e-14 51.3 14.2 2.5e-12 46.6 13.7 2.5 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 PVD35106.1 - 4.8e-09 36.7 0.7 9.6e-05 22.9 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35106.1 - 1.4e-08 35.1 0.0 0.00011 22.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35106.1 - 2.8e-08 33.4 0.5 0.042 14.4 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 PVD35106.1 - 7.3e-05 23.0 0.0 0.5 10.9 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeat PKD_channel PF08016.12 PVD35106.1 - 0.0002 20.2 4.0 0.15 10.7 0.5 2.4 2 0 0 2 2 2 2 Polycystin cation channel Ank_5 PF13857.6 PVD35106.1 - 0.00077 19.7 0.1 1.2 9.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FadA PF09403.10 PVD35106.1 - 0.032 14.7 2.7 4.5 7.8 0.5 2.7 2 0 0 2 2 2 0 Adhesion protein FadA TetR_C_37 PF18665.1 PVD35106.1 - 0.037 14.6 0.4 0.18 12.4 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ETRAMP PF09716.10 PVD35106.1 - 0.91 9.6 3.1 1 9.5 0.0 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.31 PVD35107.1 - 7.4e-23 81.0 11.9 1.1e-22 80.4 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 PVD35107.1 - 4.5e-19 68.4 0.0 1.2e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 PVD35107.1 - 1.6e-13 51.0 0.8 2.4e-07 31.2 0.1 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35107.1 - 2.3e-10 40.8 0.2 9.2e-07 29.3 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35107.1 - 1.2e-05 25.3 0.6 0.41 11.4 0.0 4.6 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 PVD35107.1 - 2.2e-05 24.7 0.0 0.11 12.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD35107.1 - 0.0053 17.2 0.1 1.1 9.8 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeat PKD_channel PF08016.12 PVD35107.1 - 1.1 7.9 16.6 0.24 10.0 1.5 3.2 2 1 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 PVD35108.1 - 3.3e-14 52.7 16.8 5.7e-14 51.9 16.8 1.4 1 0 0 1 1 1 1 Ion transport protein THOC7 PF05615.13 PVD35108.1 - 0.36 11.1 3.6 0.68 10.2 3.6 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 TRP_2 PF08344.11 PVD35109.1 - 2.5e-19 69.2 0.1 5.7e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 PVD35109.1 - 1.5e-07 31.8 0.0 5.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35109.1 - 4.5e-07 30.3 0.0 4e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35109.1 - 0.0011 19.2 1.6 0.039 14.5 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 PVD35109.1 - 0.0025 18.2 0.1 0.0097 16.3 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PVD35109.1 - 0.043 14.2 0.0 0.2 12.0 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF4926 PF16277.5 PVD35109.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) CUB PF00431.20 PVD35111.1 - 4.3e-07 30.2 0.0 7.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain DUF5418 PF17439.2 PVD35112.1 - 0.017 15.2 7.2 0.038 14.1 7.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5418) Stm1_N PF09598.10 PVD35112.1 - 0.031 15.1 0.0 0.06 14.2 0.0 1.4 1 0 0 1 1 1 0 Stm1 FH2 PF02181.23 PVD35113.1 - 6.8e-51 173.5 0.6 1e-50 172.9 0.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PH PF00169.29 PVD35113.1 - 0.059 13.9 0.3 0.2 12.2 0.3 2.0 1 0 0 1 1 1 0 PH domain TPR_8 PF13181.6 PVD35113.1 - 0.19 12.0 0.7 1.1 9.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat GAS PF13851.6 PVD35113.1 - 0.67 9.3 4.3 0.3 10.4 0.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding 7tm_1 PF00001.21 PVD35114.1 - 6.7e-39 133.8 4.2 2.2e-25 89.5 4.0 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD35114.1 - 0.0029 17.3 0.8 0.006 16.2 0.8 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD35114.1 - 0.009 15.4 6.7 0.066 12.6 0.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx CpeT PF06206.11 PVD35115.1 - 5.1e-12 46.1 0.0 9.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) VirK PF06903.12 PVD35115.1 - 0.0003 20.8 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 2 VirK protein Guanylate_cyc PF00211.20 PVD35116.1 - 8.6e-13 48.3 0.1 1.3e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD35116.1 - 6e-12 45.4 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35116.1 - 2.1e-07 30.6 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD35117.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase P68HR PF08061.11 PVD35117.1 - 0.74 10.0 2.8 1.4 9.1 0.4 2.2 2 0 0 2 2 2 0 P68HR (NUC004) repeat PBP_like_2 PF12849.7 PVD35118.1 - 2.4e-18 66.8 0.0 1.3e-17 64.4 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain OAS1_C PF10421.9 PVD35119.1 - 4e-14 52.5 0.1 8e-14 51.6 0.1 1.5 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.23 PVD35119.1 - 7.5e-06 26.2 0.2 1.6e-05 25.1 0.2 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 PVD35119.1 - 4.4e-05 23.7 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Polbeta PF18765.1 PVD35119.1 - 0.13 12.4 0.1 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase OAS1_C PF10421.9 PVD35120.1 - 1.3e-12 47.6 0.1 9.3e-06 25.3 0.0 2.4 2 1 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.23 PVD35120.1 - 4e-05 23.8 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 PVD35120.1 - 0.0011 19.1 0.0 0.0082 16.3 0.0 2.2 2 0 0 2 2 2 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Ubiquitin_2 PF14560.6 PVD35120.1 - 0.12 12.8 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain OAS1_C PF10421.9 PVD35121.1 - 2.6e-24 85.7 0.0 2.5e-12 46.7 0.1 3.1 2 1 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.23 PVD35121.1 - 4.3e-13 49.4 0.1 5.5e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 Nucleotidyltransferase domain SMODS PF18144.1 PVD35121.1 - 1.4e-10 41.6 0.0 0.00038 20.7 0.0 2.2 2 0 0 2 2 2 2 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain KRE1 PF17056.5 PVD35121.1 - 4.5e-05 23.1 0.8 0.05 13.3 0.1 2.4 2 0 0 2 2 2 2 Killer toxin-resistance protein 1 CTD_bind PF04818.13 PVD35121.1 - 0.00082 20.2 0.0 3.5 8.5 0.0 2.9 2 0 0 2 2 2 2 RNA polymerase II-binding domain. He_PIG_assoc PF10632.9 PVD35121.1 - 0.23 11.2 1.9 22 4.8 0.1 2.7 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase HA2 PF04408.23 PVD35122.1 - 6.2e-21 74.7 0.0 1.5e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PVD35122.1 - 3.3e-20 72.2 0.0 6.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PVD35122.1 - 5.2e-08 33.2 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PVD35122.1 - 0.00085 19.1 0.1 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Speriolin_C PF15059.6 PVD35123.1 - 2.9e-31 108.6 0.0 4.9e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Speriolin C-terminus 7tm_1 PF00001.21 PVD35124.1 - 7.3e-12 45.2 8.4 2.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4663 PF15668.5 PVD35125.1 - 2.5e-06 26.8 0.0 2.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) ASC PF00858.24 PVD35127.1 - 2e-48 165.5 7.2 3.3e-48 164.8 7.2 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel MG2 PF01835.19 PVD35128.1 - 2e-14 53.8 0.0 1.7e-13 50.8 0.0 2.7 2 0 0 2 2 2 1 MG2 domain A2M_BRD PF07703.14 PVD35128.1 - 5.1e-14 52.8 8.1 3e-11 43.8 0.1 4.6 5 1 0 5 5 5 2 Alpha-2-macroglobulin bait region domain A2M_recep PF07677.14 PVD35128.1 - 1.3e-12 48.2 0.1 4e-11 43.5 0.0 2.7 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain TED_complement PF07678.14 PVD35128.1 - 3.1e-12 46.1 0.6 4.4e-08 32.5 0.1 2.3 1 1 1 2 2 2 2 A-macroglobulin TED domain A2M PF00207.22 PVD35128.1 - 7.9e-10 38.5 0.3 7.1e-09 35.4 0.1 2.7 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 PVD35128.1 - 1.3e-06 28.5 0.1 4e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 PVD35128.1 - 0.00068 19.7 5.4 0.00076 19.6 0.1 3.5 4 0 0 4 4 4 1 Macroglobulin domain MG4 TOBE PF03459.17 PVD35128.1 - 0.041 14.2 0.1 1.8 8.9 0.0 3.7 3 0 0 3 3 3 0 TOBE domain TED_complement PF07678.14 PVD35129.1 - 3.1e-54 184.1 0.3 2.2e-53 181.4 0.3 2.1 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD35129.1 - 2.2e-26 92.9 0.5 8.3e-26 91.0 0.3 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD35129.1 - 1.2e-23 82.7 1.3 1.2e-23 82.7 1.3 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 PVD35129.1 - 4.6e-16 59.3 0.0 1.5e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 PVD35129.1 - 4.5e-14 52.5 0.0 1.6e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 PVD35129.1 - 1.9e-05 25.1 0.0 0.00017 22.0 0.0 2.7 3 0 0 3 3 3 1 MG2 domain MG4 PF17789.1 PVD35129.1 - 3.4e-05 23.9 0.1 0.00083 19.4 0.1 3.0 1 1 0 1 1 1 1 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 PVD35129.1 - 3.8e-05 22.9 0.0 8.4e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain DUF4681 PF15732.5 PVD35129.1 - 0.014 15.6 0.0 0.054 13.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) Prenyltrans PF00432.21 PVD35129.1 - 0.059 13.1 0.0 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 PVD35130.1 - 1.5e-141 471.0 0.2 9.5e-82 274.5 0.0 3.2 2 1 1 3 3 3 3 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD35130.1 - 1.5e-51 174.4 4.1 3.7e-27 95.4 0.0 4.9 4 0 0 4 4 4 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 PVD35130.1 - 7.5e-50 166.7 10.3 5.1e-25 87.1 1.5 3.4 2 0 0 2 2 2 2 Alpha-2-macroglobulin family A2M_recep PF07677.14 PVD35130.1 - 5.6e-34 116.7 2.3 4.9e-16 59.2 0.1 3.4 3 0 0 3 3 3 2 A-macroglobulin receptor binding domain MG2 PF01835.19 PVD35130.1 - 1.7e-32 111.8 0.2 1.1e-14 54.7 0.1 4.2 4 0 0 4 4 4 2 MG2 domain MG3 PF17791.1 PVD35130.1 - 7.9e-31 106.2 1.0 3.2e-15 56.2 0.2 3.1 2 0 0 2 2 2 2 Macroglobulin domain MG3 MG4 PF17789.1 PVD35130.1 - 1.3e-14 54.1 1.6 4.8e-06 26.6 0.1 4.5 3 2 0 3 3 3 2 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 PVD35130.1 - 1.3e-11 44.2 0.0 5.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 PVD35130.1 - 6.7e-05 22.5 0.1 3.7 7.4 0.0 4.3 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat DUF4850 PF16142.5 PVD35130.1 - 0.14 11.6 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4850) TED_complement PF07678.14 PVD35131.1 - 3.3e-89 299.0 4.9 2.7e-56 190.9 0.3 3.4 2 1 0 2 2 2 2 A-macroglobulin TED domain A2M_BRD PF07703.14 PVD35131.1 - 2.8e-50 170.3 7.5 3.3e-27 95.5 0.1 5.0 4 0 0 4 4 4 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 PVD35131.1 - 5.4e-34 116.3 0.3 2.3e-15 56.6 0.0 3.0 2 0 0 2 2 2 2 Macroglobulin domain MG3 MG2 PF01835.19 PVD35131.1 - 5.8e-34 116.4 0.6 2.5e-15 56.7 0.1 3.2 2 0 0 2 2 2 2 MG2 domain A2M_recep PF07677.14 PVD35131.1 - 1.2e-32 112.4 1.0 5.4e-17 62.3 0.2 3.0 2 0 0 2 2 2 2 A-macroglobulin receptor binding domain A2M PF00207.22 PVD35131.1 - 1.4e-19 69.7 9.6 4.3e-09 36.1 1.3 3.7 2 0 0 2 2 2 2 Alpha-2-macroglobulin family MG4 PF17789.1 PVD35131.1 - 1e-13 51.2 3.0 3.4e-05 23.9 0.1 4.7 4 2 0 4 4 4 2 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 PVD35131.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain DUF2659 PF10858.8 PVD35131.1 - 0.012 15.3 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2659) TOM6p PF15184.6 PVD35131.1 - 0.035 13.9 0.3 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Prenyltrans PF00432.21 PVD35131.1 - 0.13 12.1 0.0 10 5.9 0.0 3.2 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Melibiase_2 PF16499.5 PVD35132.1 - 2e-143 476.7 0.2 2.3e-143 476.5 0.2 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 PVD35132.1 - 7e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 PVD35132.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain DUF5126 PF17166.4 PVD35132.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Integrase_H2C2 PF17921.1 PVD35133.1 - 8e-16 57.9 0.5 1.7e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PVD35133.1 - 0.014 15.6 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger UNC-50 PF05216.13 PVD35134.1 - 1.8e-11 44.0 0.1 1.8e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 UNC-50 family Trypsin PF00089.26 PVD35135.1 - 0.056 13.3 0.5 0.13 12.1 0.2 1.7 2 0 0 2 2 2 0 Trypsin NAD_binding_2 PF03446.15 PVD35138.1 - 5e-40 137.3 0.1 7.8e-40 136.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PVD35138.1 - 1.6e-26 93.0 0.2 2.6e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 PVD35138.1 - 1.4e-08 35.2 0.0 3.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 PVD35138.1 - 0.00061 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 PVD35138.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PVD35138.1 - 0.0033 17.3 0.2 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 PVD35138.1 - 0.0051 16.4 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 PVD35138.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 PVD35138.1 - 0.05 12.6 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Sacchrp_dh_NADP PF03435.18 PVD35138.1 - 0.08 13.2 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh PF00984.19 PVD35138.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Rrn6 PF10214.9 PVD35139.1 - 0.31 9.5 13.3 0.31 9.5 13.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PRIMA1 PF16101.5 PVD35139.1 - 1.5 8.9 8.3 2 8.5 8.3 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Metallophos PF00149.28 PVD35141.1 - 2.9e-27 96.5 1.1 4.9e-27 95.8 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 PVD35141.1 - 1.2e-18 67.3 3.2 4.1e-12 46.4 0.6 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD35141.1 - 1.6e-17 61.7 3.8 3.1e-06 26.3 0.2 4.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD35141.1 - 1.3e-13 49.6 2.5 6.4e-05 22.6 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD35141.1 - 4.2e-11 41.8 3.5 4.3e-05 22.8 0.1 3.8 3 0 0 3 3 3 2 EF hand PPP5 PF08321.12 PVD35141.1 - 8.1e-10 38.9 0.8 4.9e-09 36.3 0.0 2.6 3 0 0 3 3 3 1 PPP5 TPR repeat region EF-hand_8 PF13833.6 PVD35141.1 - 3.9e-09 36.2 2.0 2.4e-06 27.3 0.1 3.7 2 1 1 3 3 3 2 EF-hand domain pair IQ PF00612.27 PVD35141.1 - 0.00025 20.6 2.8 0.00061 19.4 2.8 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_9 PF14658.6 PVD35141.1 - 0.011 16.0 0.1 0.14 12.5 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PVD35141.1 - 0.012 15.9 0.3 0.98 9.8 0.1 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD35141.1 - 0.02 14.8 3.2 0.32 11.0 0.2 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand DBC1 PF14443.6 PVD35141.1 - 0.17 11.8 0.6 4.2 7.4 0.0 2.8 3 0 0 3 3 3 0 DBC1 PHD PF00628.29 PVD35142.1 - 0.00061 19.6 5.4 0.0015 18.4 2.6 2.5 2 0 0 2 2 2 1 PHD-finger PAS_11 PF14598.6 PVD35143.1 - 1.1e-25 89.9 0.7 8.5e-21 74.2 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 PVD35143.1 - 1.1e-25 89.7 0.4 1.8e-18 66.6 0.1 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 PVD35143.1 - 3.2e-14 52.9 0.0 2.5e-10 40.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold Myb_DNA-bind_2 PF08914.11 PVD35143.1 - 7.3e-14 51.7 0.0 2.4e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Rap1 Myb domain HLH PF00010.26 PVD35143.1 - 1.2e-09 37.9 2.0 3e-09 36.7 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 PVD35143.1 - 6.5e-05 23.1 0.0 0.00036 20.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 PVD35143.1 - 0.00058 20.1 0.0 0.033 14.5 0.0 2.7 2 0 0 2 2 2 1 PAS fold zf-Tim10_DDP PF02953.15 PVD35144.1 - 6.5e-24 83.4 1.2 9.1e-24 82.9 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger dDENN PF03455.19 PVD35144.1 - 0.016 15.2 0.5 0.053 13.5 0.1 2.0 2 1 0 2 2 2 0 dDENN domain Arfaptin PF06456.13 PVD35145.1 - 3.2e-70 236.2 8.0 4.1e-70 235.9 8.0 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 PVD35145.1 - 0.025 14.3 8.7 0.041 13.6 8.7 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Lectin_C PF00059.21 PVD35146.1 - 1.6e-13 51.4 0.8 5e-13 49.7 0.8 2.0 1 0 0 1 1 1 1 Lectin C-type domain PARP PF00644.20 PVD35146.1 - 2.4e-11 43.6 0.0 1.2e-10 41.3 0.0 2.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 PVD35146.1 - 1.9e-05 24.7 0.1 0.0001 22.4 0.1 2.3 1 0 0 1 1 1 1 Macro domain UL45 PF05473.12 PVD35146.1 - 3e-05 23.8 0.1 0.00016 21.4 0.1 2.2 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Exotox-A_cataly PF09009.10 PVD35146.1 - 0.088 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Exotoxin A catalytic Lectin_C PF00059.21 PVD35147.1 - 1.3e-46 157.8 9.2 5.5e-18 65.7 0.3 7.3 6 1 1 7 7 7 6 Lectin C-type domain F5_F8_type_C PF00754.25 PVD35147.1 - 8.3e-44 148.8 2.4 2.6e-21 76.0 0.0 4.7 4 1 0 4 4 4 3 F5/8 type C domain UL45 PF05473.12 PVD35147.1 - 8.7e-06 25.5 14.3 0.021 14.5 0.3 5.1 4 1 1 5 5 5 3 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD35148.1 - 3.4e-06 27.8 0.4 4.9e-06 27.2 0.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD35148.1 - 0.1 12.2 0.1 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD35149.1 - 3.1e-62 208.0 8.8 5.7e-19 68.8 0.3 4.3 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 PVD35149.1 - 0.00056 19.6 0.6 10 5.7 0.0 4.0 4 0 0 4 4 4 3 UL45 protein, carbohydrate-binding C-type lectin-like LAMTOR PF15454.6 PVD35150.1 - 1.4e-11 44.8 4.4 1.9e-11 44.4 4.4 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Synaptobrevin PF00957.21 PVD35151.1 - 2.2e-33 113.9 0.4 3.4e-33 113.3 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PVD35151.1 - 0.0005 20.1 0.8 0.41 10.7 0.1 2.4 1 1 1 2 2 2 2 Regulated-SNARE-like domain RIFIN PF02009.16 PVD35151.1 - 0.018 14.9 0.5 0.022 14.7 0.5 1.1 1 0 0 1 1 1 0 Rifin Baculo_F PF12259.8 PVD35151.1 - 0.026 13.1 0.1 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein CCSMST1 PF15013.6 PVD35151.1 - 0.051 13.7 0.7 0.11 12.6 0.7 1.5 1 0 0 1 1 1 0 CCSMST1 family DUF2976 PF11190.8 PVD35151.1 - 0.14 11.9 1.6 0.23 11.3 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Orf78 PF06024.12 PVD35151.1 - 0.35 11.2 2.5 0.63 10.4 2.5 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Prominin PF05478.11 PVD35151.1 - 10 4.0 7.7 0.71 7.8 0.1 2.1 1 1 1 2 2 2 0 Prominin zf-C2H2 PF00096.26 PVD35154.1 - 3.9e-05 23.9 17.4 0.0034 17.8 5.2 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD35154.1 - 9.4e-05 22.7 15.3 0.00093 19.5 1.0 3.7 3 1 0 3 3 3 2 Zinc-finger double domain Zn-ribbon_8 PF09723.10 PVD35154.1 - 0.00088 19.3 5.2 0.28 11.4 1.8 2.5 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_4 PF13894.6 PVD35154.1 - 0.001 19.7 19.0 0.021 15.6 4.9 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 PVD35154.1 - 0.0058 16.2 4.4 0.74 9.5 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 PVD35154.1 - 0.017 14.9 2.3 3.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) ADK_lid PF05191.14 PVD35154.1 - 0.02 14.9 1.7 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF629 PF04780.12 PVD35154.1 - 0.027 13.0 6.6 0.048 12.2 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.6 PVD35154.1 - 0.035 13.9 0.4 0.035 13.9 0.4 3.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain XPA_N PF01286.18 PVD35154.1 - 0.045 13.8 2.0 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 XPA protein N-terminal zf-MYST PF17772.1 PVD35154.1 - 0.055 13.1 2.1 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 PVD35154.1 - 0.062 13.0 1.0 0.062 13.0 1.0 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 PVD35154.1 - 0.075 13.2 6.4 0.12 12.5 6.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.6 PVD35154.1 - 0.084 12.9 6.8 1.4 9.0 2.7 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain Rubredoxin_2 PF18073.1 PVD35154.1 - 0.099 12.4 0.4 0.099 12.4 0.4 2.9 3 1 0 3 3 3 0 Rubredoxin metal binding domain Desulfoferrod_N PF06397.12 PVD35154.1 - 0.14 11.8 2.8 5.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Keratin_matx PF04579.12 PVD35154.1 - 0.26 11.7 3.2 0.44 10.9 1.1 1.9 1 1 1 2 2 2 0 Keratin, high-sulphur matrix protein zf-C2H2_11 PF16622.5 PVD35154.1 - 0.32 10.8 10.8 0.1 12.4 3.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type PhnA_Zn_Ribbon PF08274.12 PVD35154.1 - 0.43 10.6 4.2 0.44 10.5 0.1 2.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.7 PVD35154.1 - 0.69 10.0 7.9 17 5.6 7.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.7 PVD35154.1 - 7.3 7.1 11.8 1.5 9.4 2.9 2.7 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-Mss51 PF13824.6 PVD35154.1 - 8.6 6.5 10.7 2.9e+02 1.7 10.7 2.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 7tm_1 PF00001.21 PVD35156.1 - 1.7e-24 86.6 0.8 2.5e-24 86.0 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD35156.1 - 6.3e-11 42.1 20.6 6e-07 29.1 7.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD35156.1 - 0.00021 21.0 16.5 0.00021 21.0 16.5 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PARP PF00644.20 PVD35159.1 - 2e-19 70.0 0.0 4e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 PVD35159.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Exotoxin A catalytic ART-PolyVal PF18760.1 PVD35159.1 - 0.0043 18.1 0.0 0.0076 17.3 0.0 1.4 1 0 0 1 1 1 1 ADP-Ribosyltransferase in polyvalent proteins AIG1 PF04548.16 PVD35160.1 - 3.3e-57 193.2 0.0 3.3e-57 193.2 0.0 3.1 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD35160.1 - 1.4e-06 28.4 0.0 1.4e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35160.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD35160.1 - 0.023 15.2 0.0 0.023 15.2 0.0 2.8 1 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 PVD35160.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 PVD35160.1 - 1.6 8.8 0.0 1.6 8.8 0.0 4.0 2 2 1 3 3 3 0 Dynamin family Peptidase_S64 PF08192.11 PVD35160.1 - 1.7 7.1 7.3 2.4 6.5 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3584 PF12128.8 PVD35160.1 - 2.5 5.5 31.3 3.4 5.0 31.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SOBP PF15279.6 PVD35160.1 - 3.3 8.3 10.5 5.8 7.4 10.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein AIG1 PF04548.16 PVD35161.1 - 1.4e-91 305.6 0.6 3.8e-54 183.2 0.2 4.8 4 1 1 5 5 5 2 AIG1 family MMR_HSR1 PF01926.23 PVD35161.1 - 2.6e-05 24.3 0.0 2.6e-05 24.3 0.0 3.7 3 1 0 3 3 3 2 50S ribosome-binding GTPase DUF3584 PF12128.8 PVD35161.1 - 0.00017 19.3 26.6 0.00017 19.3 26.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AIG1 PF04548.16 PVD35162.1 - 5.1e-56 189.3 0.1 5.1e-56 189.3 0.1 4.4 3 2 2 5 5 5 1 AIG1 family MMR_HSR1 PF01926.23 PVD35162.1 - 1.6e-08 34.6 0.0 1.6e-08 34.6 0.0 3.4 2 1 1 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35162.1 - 0.00037 20.1 0.0 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 PVD35162.1 - 0.67 10.3 0.0 0.67 10.3 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain PARP PF00644.20 PVD35163.1 - 7.6e-24 84.4 0.2 3.8e-23 82.1 0.2 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 PVD35163.1 - 3.5e-06 26.9 0.0 4.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Exotoxin A catalytic ART-PolyVal PF18760.1 PVD35163.1 - 0.0045 18.0 0.0 0.0064 17.5 0.0 1.3 1 0 0 1 1 1 1 ADP-Ribosyltransferase in polyvalent proteins AIG1 PF04548.16 PVD35164.1 - 2.6e-54 183.8 0.2 2.6e-54 183.8 0.2 3.6 3 1 0 4 4 4 1 AIG1 family MMR_HSR1 PF01926.23 PVD35164.1 - 2.1e-06 27.8 0.1 1e-05 25.6 0.1 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Herpes_UL35 PF04496.12 PVD35164.1 - 4.3e-05 23.8 0.2 0.00018 21.8 0.1 2.1 2 0 0 2 2 2 1 Herpesvirus UL35 family RsgA_GTPase PF03193.16 PVD35164.1 - 0.0041 17.0 0.5 0.0041 17.0 0.5 2.9 3 1 1 4 4 4 1 RsgA GTPase FeoB_N PF02421.18 PVD35164.1 - 0.0085 15.6 0.1 0.024 14.1 0.1 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 PVD35164.1 - 0.1 12.1 1.1 0.38 10.3 1.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PVD35164.1 - 0.78 10.1 4.7 18 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Acetyltransf_11 PF13720.6 PVD35164.1 - 9.7 6.7 8.8 14 6.2 0.0 4.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AIG1 PF04548.16 PVD35165.1 - 1.7e-55 187.6 0.1 1.7e-55 187.6 0.1 4.4 3 2 1 4 4 4 1 AIG1 family MMR_HSR1 PF01926.23 PVD35165.1 - 6.3e-07 29.5 0.0 6.3e-07 29.5 0.0 3.6 2 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35165.1 - 0.0049 16.4 2.8 0.0056 16.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AIG1 PF04548.16 PVD35166.1 - 1.1e-06 28.1 0.0 1.3e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 AIG1 family AIG1 PF04548.16 PVD35168.1 - 8.7e-49 165.7 0.0 8.7e-49 165.7 0.0 2.6 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PVD35168.1 - 1.8e-05 24.8 0.0 1.8e-05 24.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35168.1 - 0.0024 17.4 0.0 0.0083 15.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD35168.1 - 0.11 13.1 0.0 0.11 13.1 0.0 3.0 2 1 0 2 2 2 0 ABC transporter Borrelia_P83 PF05262.11 PVD35168.1 - 0.11 10.9 30.0 0.18 10.3 30.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_22 PF13401.6 PVD35168.1 - 0.75 10.1 7.4 1.1 9.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PVD35168.1 - 7 6.5 6.9 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 PVD35169.1 - 2e-42 144.9 0.0 2e-42 144.9 0.0 2.9 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD35169.1 - 0.051 13.7 0.0 0.051 13.7 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35169.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.2 2 1 0 2 2 2 0 Dynamin family FTR1 PF03239.14 PVD35169.1 - 0.55 9.3 0.0 0.55 9.3 0.0 2.4 2 1 0 2 2 2 0 Iron permease FTR1 family AAA_32 PF13654.6 PVD35169.1 - 0.64 8.7 21.5 1.3 7.7 21.5 1.4 1 0 0 1 1 1 0 AAA domain PRANC PF09372.10 PVD35169.1 - 2.2 8.7 4.7 1.8 8.9 0.3 2.7 1 1 2 3 3 3 0 PRANC domain ATG11 PF10377.9 PVD35169.1 - 3.2 7.8 8.9 3.6 7.7 7.3 2.0 1 1 0 1 1 1 0 Autophagy-related protein 11 AIG1 PF04548.16 PVD35170.1 - 4.6e-31 107.8 0.6 1.5e-30 106.1 0.1 1.7 1 1 0 2 2 2 1 AIG1 family Glyco_transf_7N PF13733.6 PVD35170.1 - 0.039 13.6 0.2 1.8 8.2 0.1 2.5 1 1 1 2 2 2 0 N-terminal region of glycosyl transferase group 7 AIG1 PF04548.16 PVD35171.1 - 6.1e-49 166.2 0.0 6.1e-49 166.2 0.0 3.0 2 1 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD35171.1 - 0.0014 18.7 0.7 0.0068 16.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Exonuc_VII_L PF02601.15 PVD35171.1 - 1.6 8.2 22.2 0.8 9.2 7.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF87 PF01935.17 PVD35171.1 - 2.3 8.2 14.2 5 7.2 2.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AIG1 PF04548.16 PVD35172.1 - 2.7e-147 487.6 10.0 1.4e-50 171.6 0.0 4.9 5 1 1 6 6 6 3 AIG1 family MMR_HSR1 PF01926.23 PVD35172.1 - 2.7e-14 53.2 4.9 2.6e-05 24.3 0.0 4.1 4 0 0 4 4 3 3 50S ribosome-binding GTPase T2SSE PF00437.20 PVD35172.1 - 1.1e-06 28.0 5.7 0.062 12.3 0.8 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein FeoB_N PF02421.18 PVD35172.1 - 1e-05 25.1 4.2 0.044 13.3 0.1 3.9 4 0 0 4 4 4 2 Ferrous iron transport protein B AAA_7 PF12775.7 PVD35172.1 - 8e-05 22.2 5.0 1.3 8.5 0.1 4.1 3 1 1 4 4 4 3 P-loop containing dynein motor region Dynamin_N PF00350.23 PVD35172.1 - 0.0015 18.6 29.5 0.037 14.1 0.2 6.0 5 2 1 6 6 5 3 Dynamin family AAA_22 PF13401.6 PVD35172.1 - 0.0025 18.1 2.7 1.5 9.1 0.0 3.6 3 2 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 PVD35172.1 - 0.0032 16.9 3.9 1.2 8.4 0.0 3.1 3 0 0 3 3 3 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 PVD35172.1 - 0.013 15.4 13.0 0.65 9.9 0.0 4.4 4 0 0 4 4 4 0 RsgA GTPase Roc PF08477.13 PVD35172.1 - 0.042 14.1 0.2 17 5.7 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PVD35172.1 - 0.097 13.0 7.7 4 7.8 0.0 4.5 3 1 1 4 4 4 0 AAA ATPase domain AAA_33 PF13671.6 PVD35172.1 - 0.19 11.9 7.7 0.65 10.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain SpoVAD PF07451.11 PVD35172.1 - 0.23 10.1 0.6 1.5 7.5 0.0 2.3 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) AAA_29 PF13555.6 PVD35172.1 - 0.88 9.4 11.0 0.57 10.0 0.6 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 PVD35172.1 - 0.95 8.8 14.7 1.1 8.5 0.0 4.9 4 1 1 5 5 5 0 Gtr1/RagA G protein conserved region DUF2937 PF11157.8 PVD35172.1 - 2.1 8.1 6.8 0.37 10.5 1.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) DUF5320 PF17253.2 PVD35172.1 - 3.1 8.9 4.4 22 6.2 4.4 2.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Septin PF00735.18 PVD35172.1 - 5.5 6.2 23.4 0.28 10.4 0.1 4.9 5 0 0 5 5 5 0 Septin AIG1 PF04548.16 PVD35173.1 - 8.1e-55 185.4 0.0 8.1e-55 185.4 0.0 2.6 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PVD35173.1 - 2.3e-05 24.4 0.0 2.3e-05 24.4 0.0 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD35173.1 - 0.063 13.8 0.0 0.063 13.8 0.0 3.5 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 PVD35173.1 - 0.085 12.6 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Borrelia_P83 PF05262.11 PVD35173.1 - 2.4 6.6 31.4 4 5.8 31.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.7 PVD35173.1 - 2.8 6.0 21.4 0.0089 14.2 9.8 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF4200 PF13863.6 PVD35173.1 - 3.2 8.2 55.9 1.1 9.7 26.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TFIIA PF03153.13 PVD35173.1 - 4.3 7.2 28.3 3.7 7.4 16.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AIG1 PF04548.16 PVD35174.1 - 4.2e-39 134.1 0.0 4.6e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35174.1 - 0.00018 21.5 0.0 0.00023 21.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PVD35175.1 - 2.8e-69 232.7 0.0 7.4e-59 198.6 0.0 3.4 2 1 0 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 PVD35175.1 - 6.7e-08 32.6 0.0 6.7e-08 32.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35175.1 - 0.011 15.8 0.1 0.26 11.3 0.0 4.2 2 2 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 PVD35175.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase DUF4407 PF14362.6 PVD35175.1 - 1.3 8.3 20.1 3.6 6.9 20.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PVD35175.1 - 2.6 7.6 20.2 0.93 9.0 16.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.11 PVD35175.1 - 4 7.4 30.6 7 6.6 30.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ABC_tran PF00005.27 PVD35175.1 - 5.5 7.5 14.9 6.9e+02 0.7 14.9 3.0 1 1 0 1 1 1 0 ABC transporter Atg14 PF10186.9 PVD35175.1 - 8.8 5.3 24.3 16 4.5 24.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AIG1 PF04548.16 PVD35176.1 - 5.2e-27 94.6 0.0 5.2e-27 94.6 0.0 2.6 1 1 2 3 3 3 1 AIG1 family DUF3584 PF12128.8 PVD35176.1 - 0.085 10.4 31.5 0.14 9.7 31.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 PVD35176.1 - 4.3 7.3 9.0 0.86 9.6 0.3 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Asp-B-Hydro_N PF05279.11 PVD35176.1 - 6.2 6.8 33.3 11 6.0 33.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ApoO PF09769.9 PVD35176.1 - 8.5 6.4 8.6 51 3.8 0.0 3.2 2 1 0 3 3 3 0 Apolipoprotein O AIG1 PF04548.16 PVD35177.1 - 2.7e-46 157.6 0.0 5.5e-46 156.6 0.0 1.5 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35177.1 - 3.5e-05 23.9 0.2 8.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35177.1 - 0.0049 16.4 0.1 0.0098 15.4 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Nup88 PF10168.9 PVD35177.1 - 0.022 12.6 3.6 0.036 11.9 3.6 1.2 1 0 0 1 1 1 0 Nuclear pore component RsgA_GTPase PF03193.16 PVD35177.1 - 0.067 13.1 0.5 0.14 12.0 0.5 1.6 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 PVD35177.1 - 0.14 12.2 4.5 18 5.3 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_21 PF13304.6 PVD35177.1 - 0.2 11.4 1.4 12 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 PVD35177.1 - 1.4 9.4 6.8 2.4 8.7 1.5 2.5 2 1 0 2 2 2 0 ABC transporter AIG1 PF04548.16 PVD35178.1 - 4.5e-50 169.9 0.0 4.5e-50 169.9 0.0 2.4 1 1 2 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD35178.1 - 1e-07 32.0 0.0 4.3e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35178.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 PVD35178.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Caldesmon PF02029.15 PVD35178.1 - 4.2 6.0 51.7 8.1 5.1 51.7 1.3 1 0 0 1 1 1 0 Caldesmon MerR PF00376.23 PVD35179.1 - 0.074 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 MerR family regulatory protein AIG1 PF04548.16 PVD35180.1 - 3.8e-54 183.2 0.9 6.8e-54 182.4 0.0 1.9 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35180.1 - 2e-06 27.9 0.0 2e-06 27.9 0.0 2.1 2 1 0 2 2 1 1 50S ribosome-binding GTPase HHH_5 PF14520.6 PVD35180.1 - 0.0015 19.0 0.1 0.91 10.2 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain FeoB_N PF02421.18 PVD35180.1 - 0.0079 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD35180.1 - 0.024 15.2 0.0 0.024 15.2 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 PVD35180.1 - 0.092 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 PVD35180.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.0 2 2 0 2 2 1 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 PVD35180.1 - 0.24 11.1 9.3 0.38 10.4 6.2 2.1 2 0 0 2 2 2 0 AAA ATPase domain Exonuc_VII_L PF02601.15 PVD35180.1 - 0.29 10.7 11.8 0.51 9.9 11.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit RsgA_GTPase PF03193.16 PVD35180.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 PVD35180.1 - 0.45 10.8 0.0 0.45 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 PVD35181.1 - 1.3e-55 188.0 0.2 1.3e-55 188.0 0.2 3.2 2 1 2 4 4 3 1 AIG1 family MMR_HSR1 PF01926.23 PVD35181.1 - 1.2e-06 28.6 0.1 1.2e-06 28.6 0.1 3.0 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 PVD35181.1 - 8.2e-05 22.5 18.3 0.00021 21.1 18.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF812 PF05667.11 PVD35181.1 - 0.0051 15.8 33.8 0.0081 15.1 33.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) LMBR1 PF04791.16 PVD35181.1 - 0.056 12.3 14.0 0.079 11.9 14.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ID PF18543.1 PVD35181.1 - 0.06 13.4 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Intracellular delivery domain RsgA_GTPase PF03193.16 PVD35181.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase Gtr1_RagA PF04670.12 PVD35181.1 - 0.36 10.1 0.0 0.36 10.1 0.0 3.0 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region SCVP PF17619.2 PVD35181.1 - 0.9 10.4 0.0 0.9 10.4 0.0 4.0 2 1 2 4 4 4 0 Secreted clade V proteins V_ATPase_I PF01496.19 PVD35181.1 - 0.91 7.4 24.7 1.6 6.5 24.7 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup88 PF10168.9 PVD35181.1 - 8.3 4.1 36.8 12 3.5 36.8 1.2 1 0 0 1 1 1 0 Nuclear pore component FUSC PF04632.12 PVD35181.1 - 9 4.7 7.1 13 4.1 7.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Profilin PF00235.19 PVD35182.1 - 4.1e-16 59.4 0.0 4.5e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Profilin DUF4407 PF14362.6 PVD35182.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4449 PF14613.6 PVD35183.1 - 0.0018 18.4 0.7 0.0018 18.4 0.7 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4449) Sulfate_transp PF00916.20 PVD35184.1 - 1.3e-109 366.4 22.8 1.7e-109 366.1 22.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD35184.1 - 0.034 13.8 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain Abhydrolase_6 PF12697.7 PVD35187.1 - 2.9e-30 106.5 0.0 2.3e-29 103.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD35187.1 - 3.3e-12 46.6 0.0 6.4e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD35187.1 - 1.9e-08 33.9 0.0 3.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PVD35187.1 - 1.6e-05 24.8 0.1 0.00015 21.6 0.1 2.3 1 1 1 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 PVD35187.1 - 3.2e-05 24.2 0.0 8.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain COesterase PF00135.28 PVD35187.1 - 0.00051 19.0 0.3 0.48 9.2 0.0 2.4 2 1 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 PVD35187.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 PVD35187.1 - 0.0024 17.8 0.6 0.012 15.5 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 PVD35187.1 - 0.0034 16.4 0.0 0.0049 15.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 PVD35187.1 - 0.0043 16.7 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Lipase_3 PF01764.25 PVD35187.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2052 PF09747.9 PVD35187.1 - 0.03 14.4 0.8 0.03 14.4 0.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Abhydrolase_2 PF02230.16 PVD35187.1 - 0.039 13.7 0.1 7.6 6.3 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 PVD35187.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) C2 PF00168.30 PVD35188.1 - 1.1e-16 61.0 0.1 0.00021 21.5 0.0 6.3 7 1 0 7 7 7 4 C2 domain SDP_N PF12278.8 PVD35188.1 - 3 8.0 15.7 5.5 7.1 13.8 2.5 2 0 0 2 2 2 0 Sex determination protein N terminal Corona_nucleoca PF00937.18 PVD35188.1 - 7.1 5.6 16.8 19 4.2 16.8 1.7 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein IQ PF00612.27 PVD35189.1 - 4.6e-11 41.5 11.0 4.8e-05 22.8 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif FadA PF09403.10 PVD35189.1 - 0.053 14.0 14.8 1.1 9.7 0.0 3.3 2 0 0 2 2 2 0 Adhesion protein FadA Heme_oxygenase PF01126.20 PVD35189.1 - 1.7 8.3 9.5 0.71 9.6 6.1 2.0 2 0 0 2 2 2 0 Heme oxygenase FAM47 PF14642.6 PVD35190.1 - 1.1e-05 25.2 0.6 3.5e-05 23.5 0.3 1.9 1 1 0 1 1 1 1 FAM47 family DNA_pol_phi PF04931.13 PVD35190.1 - 0.021 12.9 9.1 0.033 12.3 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi bZIP_2 PF07716.15 PVD35191.1 - 1.9e-12 47.1 14.3 1.9e-12 47.1 14.3 2.3 1 1 1 2 2 2 1 Basic region leucine zipper Rootletin PF15035.6 PVD35191.1 - 0.0016 18.5 2.6 0.0024 17.9 2.6 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 PVD35191.1 - 0.0051 16.9 15.6 0.01 15.9 15.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor JIP_LZII PF16471.5 PVD35191.1 - 0.021 15.0 2.3 0.042 14.0 2.3 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_Maf PF03131.17 PVD35191.1 - 0.028 14.9 10.2 0.06 13.9 10.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor KASH_CCD PF14662.6 PVD35191.1 - 0.053 13.3 4.4 0.092 12.6 4.4 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Homeodomain PF00046.29 PVD35193.1 - 3.2e-14 52.5 0.5 5.5e-14 51.8 0.5 1.3 1 0 0 1 1 1 1 Homeodomain RabGAP-TBC PF00566.18 PVD35194.1 - 1.1e-12 48.1 5.3 1.1e-12 48.1 5.3 1.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain SPACA9 PF15120.6 PVD35194.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF2043 PF09740.9 PVD35195.1 - 0.0092 16.6 0.3 0.017 15.8 0.3 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) 7tm_1 PF00001.21 PVD35196.1 - 1.3e-39 136.1 18.0 1.6e-39 135.8 18.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD35196.1 - 1.3e-07 31.6 17.6 1.3e-07 31.6 17.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD35196.1 - 1.8e-05 24.6 15.1 3.7e-05 23.6 15.1 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD35196.1 - 3.3e-05 23.4 16.8 4.3e-05 23.0 16.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ABM PF03992.16 PVD35196.1 - 0.22 11.7 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Git3 PF11710.8 PVD35196.1 - 1.8 8.3 17.9 3.9 7.2 17.9 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 PVD35197.1 - 3.4e-11 43.0 0.2 4.2e-11 42.7 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD35197.1 - 0.0008 18.9 2.5 0.00099 18.6 2.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 PVD35197.1 - 0.0054 16.1 3.0 0.0068 15.8 3.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 PVD35198.1 - 6.5e-42 143.7 14.5 1.1e-41 142.9 14.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD35198.1 - 6.2e-09 35.9 10.7 8.2e-09 35.5 10.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD35198.1 - 5.2e-06 26.4 13.4 9.6e-06 25.5 13.4 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD35198.1 - 9.8e-06 25.1 11.7 1.3e-05 24.8 11.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 PVD35198.1 - 0.0012 18.3 12.1 0.0022 17.4 12.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Git3 PF11710.8 PVD35198.1 - 1.1 9.0 14.7 0.27 11.0 10.6 1.7 1 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PGK PF00162.19 PVD35199.1 - 2.6e-132 441.3 2.7 4.1e-132 440.7 2.7 1.3 1 1 0 1 1 1 1 Phosphoglycerate kinase PXA PF02194.15 PVD35200.1 - 9.6e-32 110.4 2.7 9.6e-32 110.4 2.7 2.5 2 1 1 3 3 3 1 PXA domain Nexin_C PF08628.12 PVD35200.1 - 9.9e-25 87.3 0.3 4.6e-24 85.1 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.19 PVD35200.1 - 3.6e-20 72.4 0.5 3.4e-19 69.2 0.4 2.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.24 PVD35200.1 - 1.2e-07 31.7 0.0 6.3e-07 29.4 0.0 2.3 1 0 0 1 1 1 1 PX domain Cortex-I_coil PF09304.10 PVD35200.1 - 0.013 15.7 1.9 0.061 13.6 1.9 2.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil PH PF00169.29 PVD35201.1 - 1.2e-14 54.7 0.1 3e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 PVD35201.1 - 3.7e-06 27.2 0.0 8.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 PVD35201.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4460 PF14687.6 PVD35201.1 - 0.59 10.2 3.1 0.62 10.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) Neur_chan_memb PF02932.16 PVD35202.1 - 1.7e-11 44.6 0.3 1.8e-11 44.6 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro2_C5 PF18565.1 PVD35203.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 DUF2206 PF09971.9 PVD35203.1 - 0.23 10.2 0.0 0.29 9.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) SelP_C PF04593.14 PVD35204.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, C terminal region AIG1 PF04548.16 PVD35205.1 - 2.1e-36 125.2 0.1 2.7e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35205.1 - 1.6e-07 31.4 0.2 3.2e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35205.1 - 8.2e-05 22.7 4.8 0.15 12.1 0.5 2.9 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 PVD35205.1 - 0.0028 17.2 0.1 0.0042 16.6 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 PVD35205.1 - 0.0029 17.8 0.2 0.0092 16.2 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD35205.1 - 0.0041 17.0 1.3 0.012 15.5 1.3 1.8 1 1 0 1 1 1 1 RsgA GTPase DUF5062 PF16691.5 PVD35205.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) ABC_tran PF00005.27 PVD35205.1 - 0.084 13.4 2.5 0.39 11.2 2.2 2.1 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.16 PVD35206.1 - 1.5e-57 194.4 2.0 6.1e-33 113.9 0.1 2.8 3 0 0 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 PVD35206.1 - 1.8e-08 34.5 0.1 0.00031 20.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Septin PF00735.18 PVD35206.1 - 6.2e-05 22.4 0.2 0.0006 19.2 0.1 2.1 2 0 0 2 2 2 1 Septin PLA2_B PF01735.18 PVD35206.1 - 0.066 11.6 0.5 0.099 11.0 0.5 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Gtr1_RagA PF04670.12 PVD35206.1 - 0.071 12.4 0.2 0.63 9.3 0.2 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 PVD35207.1 - 3.8e-11 42.7 1.3 3.8e-11 42.7 1.3 3.2 1 1 2 3 3 3 1 AIG1 family THRAP3_BCLAF1 PF15440.6 PVD35207.1 - 0.28 10.2 41.3 0.37 9.7 41.3 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Peptidase_S46 PF10459.9 PVD35207.1 - 1.2 7.6 32.6 1.8 7.1 32.6 1.2 1 0 0 1 1 1 0 Peptidase S46 Ndc1_Nup PF09531.10 PVD35207.1 - 6.5 5.3 13.2 9.3 4.8 13.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3652 PF12372.8 PVD35208.1 - 0.19 11.6 22.3 46 4.0 0.2 7.4 1 1 4 5 5 5 0 Huntingtin protein region MSG PF02349.15 PVD35208.1 - 7.7 6.8 8.8 85 3.4 0.7 3.1 1 1 1 2 2 2 0 Major surface glycoprotein AIG1 PF04548.16 PVD35209.1 - 4.5e-36 124.2 0.0 6.5e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35209.1 - 1.2e-07 31.8 0.3 1.9e-07 31.1 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35209.1 - 1.7e-05 25.0 4.4 0.025 14.6 0.5 3.0 2 2 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD35209.1 - 0.0012 18.8 0.5 0.0028 17.6 0.5 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PVD35209.1 - 0.011 16.3 2.5 0.13 12.8 2.4 2.2 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 PVD35209.1 - 0.043 13.3 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 PVD35209.1 - 0.043 14.0 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5062 PF16691.5 PVD35209.1 - 0.044 13.9 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) AIG1 PF04548.16 PVD35210.1 - 6.7e-54 182.4 0.2 6.7e-54 182.4 0.2 2.0 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PVD35210.1 - 3e-11 43.4 0.0 3e-11 43.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35210.1 - 3.3e-05 23.5 0.0 7.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD35210.1 - 0.00057 20.4 6.4 0.031 14.8 6.4 2.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD35210.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase Dynein_light PF01221.18 PVD35210.1 - 0.28 11.5 0.2 0.28 11.5 0.2 3.7 1 1 3 4 4 4 0 Dynein light chain type 1 Asp-B-Hydro_N PF05279.11 PVD35210.1 - 1.2 9.1 20.5 1.8 8.6 20.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dynamin_N PF00350.23 PVD35210.1 - 2.8 8.0 0.0 2 8.5 0.3 4.0 2 2 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 PVD35210.1 - 2.9 7.4 11.7 4 6.9 11.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gtr1_RagA PF04670.12 PVD35210.1 - 6.2 6.1 13.2 2e+02 1.2 13.2 2.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Cadherin PF00028.17 PVD35211.1 - 4.4e-99 325.1 0.1 2e-21 76.2 0.0 6.6 6 0 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 PVD35211.1 - 4.9e-07 29.7 5.6 1.2 9.2 0.0 5.5 5 1 0 5 5 5 3 Cadherin-like Cadherin_pro PF08758.11 PVD35211.1 - 0.00075 19.6 0.0 5.2 7.3 0.0 4.2 4 1 0 4 4 4 2 Cadherin prodomain like Cadherin_4 PF17803.1 PVD35211.1 - 0.037 14.6 35.4 0.17 12.5 0.9 5.4 5 0 0 5 5 5 0 Bacterial cadherin-like domain Y_Y_Y PF07495.13 PVD35211.1 - 0.04 13.9 0.0 38 4.3 0.0 4.2 4 0 0 4 4 4 0 Y_Y_Y domain SusE PF14292.6 PVD35211.1 - 0.11 12.8 4.8 3.2 8.0 0.2 3.7 4 1 1 5 5 5 0 SusE outer membrane protein Big_9 PF17963.1 PVD35211.1 - 0.12 13.1 30.0 0.49 11.2 3.6 5.2 5 1 0 5 5 5 0 Bacterial Ig domain Cadherin_2 PF08266.12 PVD35211.1 - 0.45 10.4 3.2 36 4.3 0.0 4.8 7 0 0 7 7 7 0 Cadherin-like Cadherin PF00028.17 PVD35212.1 - 2.7e-44 149.5 0.3 8.2e-16 58.2 0.0 3.5 4 0 0 4 4 4 3 Cadherin domain Cadherin_3 PF16184.5 PVD35212.1 - 0.00046 20.2 1.0 0.19 11.7 0.0 3.3 2 1 0 3 3 3 2 Cadherin-like MFS_1 PF07690.16 PVD35213.1 - 1.8e-20 73.2 1.1 1.7e-18 66.7 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Stanniocalcin PF03298.13 PVD35215.1 - 1.9e-08 33.9 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family tRNA-synt_1 PF00133.22 PVD35216.1 - 8.7e-29 100.2 0.8 3e-13 48.9 0.2 3.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PVD35216.1 - 2.7e-19 69.2 0.1 4.9e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PVD35216.1 - 1e-17 64.5 0.0 2.6e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PVD35216.1 - 7.6e-07 28.8 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PVD35216.1 - 0.043 12.7 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) Anoctamin PF04547.12 PVD35218.1 - 9.7e-128 426.8 11.3 1.4e-127 426.3 11.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PVD35218.1 - 6.1e-28 98.1 0.3 1e-27 97.4 0.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Prominin PF05478.11 PVD35218.1 - 0.017 13.1 1.6 0.025 12.6 1.6 1.1 1 0 0 1 1 1 0 Prominin GEMIN8 PF15348.6 PVD35220.1 - 0.043 14.1 4.6 0.046 14.0 4.6 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Med13_C PF06333.12 PVD35220.1 - 0.066 12.5 11.4 0.069 12.4 11.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Presenilin PF01080.17 PVD35220.1 - 1.5 7.5 6.3 1.6 7.4 6.3 1.0 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 PVD35220.1 - 4.6 5.7 8.7 4.3 5.8 8.7 1.0 1 0 0 1 1 1 0 Macoilin family DUF908 PF06012.12 PVD35220.1 - 6.5 6.1 14.2 6.7 6.0 14.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PDGF PF00341.17 PVD35221.1 - 0.0069 16.7 4.5 0.0069 16.7 4.5 2.2 2 0 0 2 2 2 1 PDGF/VEGF domain SNAD1 PF18744.1 PVD35223.1 - 0.083 12.7 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 tRNA_bind_3 PF17176.4 PVD35223.1 - 0.54 10.6 5.8 0.55 10.5 0.2 2.6 3 0 0 3 3 3 0 tRNA-binding domain FERM_M PF00373.18 PVD35225.1 - 2.4e-15 57.0 2.3 2.4e-15 57.0 2.3 1.9 2 0 0 2 2 2 1 FERM central domain PDZ PF00595.24 PVD35225.1 - 5.4e-09 36.3 0.0 1.6e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD35225.1 - 1e-06 28.5 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD35225.1 - 4.1e-05 23.8 0.0 0.00028 21.1 0.0 2.4 2 0 0 2 2 2 1 PDZ domain FERM_N PF09379.10 PVD35225.1 - 0.00033 20.5 0.1 0.0013 18.7 0.2 2.0 2 0 0 2 2 2 1 FERM N-terminal domain WW PF00397.26 PVD35225.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 2.6 2 0 0 2 2 2 1 WW domain FERM_f0 PF16511.5 PVD35225.1 - 0.0065 16.8 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM BCAS3 PF12490.8 PVD35227.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF2205 PF10224.9 PVD35228.1 - 2.5e-26 91.5 1.2 3.4e-26 91.0 1.2 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 PVD35228.1 - 0.0004 20.5 5.9 0.034 14.4 1.5 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper CENP-H PF05837.12 PVD35228.1 - 0.0019 18.6 1.3 0.0026 18.1 1.3 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) HalX PF08663.10 PVD35228.1 - 0.0035 17.6 1.2 0.0058 16.9 1.2 1.3 1 0 0 1 1 1 1 HalX domain FlaC_arch PF05377.11 PVD35228.1 - 0.0059 17.0 1.4 0.011 16.1 1.4 1.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 PVD35228.1 - 0.029 14.4 0.6 0.055 13.6 0.4 1.5 1 1 0 1 1 1 0 bZIP transcription factor Sas10_Utp3 PF04000.15 PVD35228.1 - 0.032 14.8 1.8 0.2 12.3 0.9 2.0 2 0 0 2 2 2 0 Sas10/Utp3/C1D family YabA PF06156.13 PVD35228.1 - 0.045 14.4 1.0 0.064 13.9 1.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA zf-HC5HC2H_2 PF13832.6 PVD35229.1 - 1.1e-30 106.0 6.1 1.1e-30 106.0 6.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PVD35229.1 - 7.4e-26 90.2 4.2 7.4e-26 90.2 4.2 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 PVD35229.1 - 5.8e-12 45.0 5.1 5.8e-12 45.0 5.1 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 PVD35229.1 - 4.2e-10 39.3 9.3 4.2e-10 39.3 9.3 3.1 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 PVD35229.1 - 7e-08 33.0 0.6 7e-08 33.0 0.6 3.8 4 1 0 4 4 4 1 Enhancer of polycomb-like zf-PHD-like PF15446.6 PVD35229.1 - 0.0018 17.9 2.6 0.0018 17.9 2.6 3.6 4 0 0 4 4 4 1 PHD/FYVE-zinc-finger like domain zf-Tim10_DDP PF02953.15 PVD35230.1 - 7.8e-22 76.7 2.3 9.7e-22 76.4 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ALG11_N PF15924.5 PVD35232.1 - 1.2e-92 309.7 0.5 1.9e-92 309.0 0.1 1.5 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 PVD35232.1 - 3.2e-24 85.4 0.0 5.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD35232.1 - 1.4e-13 51.4 0.0 8.9e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PVD35232.1 - 0.0013 18.8 0.1 0.0067 16.4 0.1 2.3 2 2 0 2 2 2 1 Glycosyltransferase Family 4 vMSA PF00695.19 PVD35232.1 - 0.032 13.3 0.2 0.051 12.7 0.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus HMA PF00403.26 PVD35233.1 - 1.2e-101 333.2 8.7 6.1e-13 49.0 0.0 8.7 8 0 0 8 8 8 8 Heavy-metal-associated domain Hydrolase PF00702.26 PVD35233.1 - 6.1e-55 186.8 2.7 1.5e-53 182.2 0.7 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PVD35233.1 - 1e-45 155.5 3.3 1e-45 155.5 3.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase RRM_3 PF08777.11 PVD35233.1 - 4e-05 23.6 0.0 1.5 8.9 0.0 4.7 4 0 0 4 4 4 2 RNA binding motif Hydrolase_3 PF08282.12 PVD35233.1 - 4.9e-05 23.2 1.8 0.00011 22.1 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PVD35233.1 - 0.0024 17.9 0.2 0.071 13.2 0.1 3.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GFA PF04828.14 PVD35233.1 - 0.43 11.0 12.1 23 5.4 0.1 5.7 7 0 0 7 7 7 0 Glutathione-dependent formaldehyde-activating enzyme CbiM PF01891.16 PVD35233.1 - 1.6 8.6 10.8 0.66 9.8 3.9 3.2 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region DUF3487 PF11990.8 PVD35233.1 - 4.9 7.1 6.6 0.39 10.6 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Stanniocalcin PF03298.13 PVD35234.1 - 4.7e-07 29.3 0.9 6e-07 29.0 0.9 1.2 1 0 0 1 1 1 1 Stanniocalcin family Carb_anhydrase PF00194.21 PVD35235.1 - 7.4e-44 150.2 0.0 9.5e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase BACK PF07707.15 PVD35237.1 - 2.8e-11 43.4 0.6 4.6e-11 42.7 0.6 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 PVD35238.1 - 4.1e-22 78.5 0.9 5.1e-22 78.2 0.9 1.1 1 0 0 1 1 1 1 BTB/POZ domain FRG1 PF06229.12 PVD35239.1 - 4.2e-74 248.4 0.0 5.7e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 PVD35239.1 - 2.7e-09 37.2 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Fascin domain Cullin_binding PF03556.15 PVD35240.1 - 3.1e-31 108.3 0.5 4.8e-31 107.7 0.5 1.3 1 0 0 1 1 1 1 Cullin binding Peptidase_M15_3 PF08291.11 PVD35240.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M15 AAA_6 PF12774.7 PVD35241.1 - 2.4e-128 427.7 0.0 7.1e-128 426.2 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD35241.1 - 1.4e-110 370.2 6.2 1.4e-110 370.2 6.2 3.5 3 0 0 3 3 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 PVD35241.1 - 4.4e-72 241.8 3.1 4.4e-72 241.8 3.1 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 PVD35241.1 - 7.9e-51 172.9 0.0 2.8e-50 171.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 PVD35241.1 - 3.2e-41 141.7 0.2 3.2e-41 141.7 0.2 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 PVD35241.1 - 8.1e-38 129.2 0.0 5e-36 123.4 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 PVD35241.1 - 8.7e-37 127.0 0.0 8.7e-37 127.0 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 PVD35241.1 - 1.8e-36 125.4 0.0 4.7e-36 124.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD35241.1 - 2.2e-36 124.9 0.1 4.4e-24 85.0 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) MT PF12777.7 PVD35241.1 - 9.5e-29 100.5 8.6 9.5e-29 100.5 8.6 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 PVD35241.1 - 4.9e-28 97.9 1.1 5.7e-24 84.6 0.0 3.4 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_16 PF13191.6 PVD35241.1 - 2e-08 34.8 10.6 0.013 15.9 0.0 6.8 6 1 0 6 6 4 2 AAA ATPase domain AAA PF00004.29 PVD35241.1 - 2.9e-07 31.0 0.0 1.6 9.1 0.0 5.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD35241.1 - 1.1e-06 29.0 6.5 0.14 12.5 0.0 6.3 6 1 1 7 7 6 2 AAA domain AAA_30 PF13604.6 PVD35241.1 - 1.9e-05 24.4 0.8 0.029 14.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 PVD35241.1 - 6.5e-05 22.9 5.2 0.078 12.9 0.0 4.9 5 0 0 5 5 5 1 RsgA GTPase ATPase_2 PF01637.18 PVD35241.1 - 0.00065 19.7 3.1 0.022 14.7 0.0 3.4 4 0 0 4 4 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PVD35241.1 - 0.00089 19.0 0.0 0.059 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PVD35241.1 - 0.0017 18.1 0.4 0.032 14.0 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein ATG16 PF08614.11 PVD35241.1 - 0.0032 17.7 8.3 0.0032 17.7 8.3 4.5 4 0 0 4 4 3 1 Autophagy protein 16 (ATG16) Rad17 PF03215.15 PVD35241.1 - 0.0053 16.7 0.1 30 4.5 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain Dynein_AAA_lid PF17852.1 PVD35241.1 - 0.0062 16.6 0.1 0.23 11.5 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD35241.1 - 0.01 16.0 0.2 0.05 13.8 0.2 2.2 1 0 0 1 1 1 0 AAA+ lid domain PhoH PF02562.16 PVD35241.1 - 0.014 14.9 0.3 0.14 11.6 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_18 PF13238.6 PVD35241.1 - 0.018 15.6 0.0 3.1 8.4 0.0 4.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD35241.1 - 0.046 13.6 0.1 7.3 6.5 0.0 3.2 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 PVD35241.1 - 0.067 13.6 0.0 12 6.3 0.0 3.6 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 PVD35241.1 - 0.074 12.1 0.0 0.64 9.0 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 PVD35241.1 - 0.074 13.3 0.4 6 7.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain GIT_CC PF16559.5 PVD35241.1 - 0.26 11.2 10.1 5 7.1 0.1 4.7 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran PF00005.27 PVD35241.1 - 0.97 10.0 0.0 0.97 10.0 0.0 5.1 6 0 0 6 6 3 0 ABC transporter HCMV_UL139 PF12507.8 PVD35241.1 - 3.2 8.2 7.7 2 8.8 4.7 2.3 2 0 0 2 2 1 0 Human Cytomegalovirus UL139 protein PT-VENN PF04829.13 PVD35244.1 - 0.66 10.1 3.0 1.9 8.6 3.0 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Cadherin PF00028.17 PVD35246.1 - 0 1044.7 39.6 1.7e-24 86.1 0.3 20.3 20 0 0 20 20 20 19 Cadherin domain Cadherin_2 PF08266.12 PVD35246.1 - 2.1e-23 81.9 0.0 0.28 11.1 0.0 14.5 16 0 0 16 16 16 5 Cadherin-like Cadherin_3 PF16184.5 PVD35246.1 - 3.2e-20 72.2 34.9 0.075 13.0 0.0 14.0 13 1 1 14 14 14 8 Cadherin-like RET_CLD1 PF17756.1 PVD35246.1 - 1e-14 54.9 0.0 0.017 15.4 0.0 9.7 10 1 1 11 11 11 3 RET Cadherin like domain 1 Cadherin_pro PF08758.11 PVD35246.1 - 7.1e-12 45.3 0.2 0.18 12.0 0.0 8.2 8 0 0 8 8 8 1 Cadherin prodomain like Cadherin_4 PF17803.1 PVD35246.1 - 0.0004 20.9 89.3 0.079 13.6 1.8 14.6 15 0 0 15 15 15 6 Bacterial cadherin-like domain PepSY PF03413.19 PVD35246.1 - 0.0027 18.2 7.1 8.6 7.0 0.1 6.4 5 0 0 5 5 5 1 Peptidase propeptide and YPEB domain PEPCK_ATP PF01293.20 PVD35246.1 - 0.0093 14.7 0.5 1 7.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase ChitinaseA_N PF08329.10 PVD35246.1 - 0.11 12.2 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Cadherin PF00028.17 PVD35247.1 - 2.4e-76 252.3 7.2 1.1e-17 64.2 0.1 5.7 5 0 0 5 5 5 5 Cadherin domain Cadherin_pro PF08758.11 PVD35247.1 - 4.1e-05 23.7 0.0 2.8 8.2 0.0 4.3 4 0 0 4 4 4 1 Cadherin prodomain like Cadherin_C PF01049.17 PVD35247.1 - 0.00026 21.4 0.5 0.0036 17.7 0.0 2.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region RET_CLD1 PF17756.1 PVD35247.1 - 0.0027 18.0 0.1 4.9 7.5 0.0 3.5 3 0 0 3 3 3 1 RET Cadherin like domain 1 ECSCR PF15820.5 PVD35247.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Luteo_PO PF04662.13 PVD35247.1 - 0.16 11.6 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Luteovirus P0 protein RCR PF12273.8 PVD35247.1 - 0.61 10.7 0.0 0.61 10.7 0.0 3.9 5 0 0 5 5 5 0 Chitin synthesis regulation, resistance to Congo red SusE PF14292.6 PVD35247.1 - 0.74 10.1 6.0 0.15 12.3 0.9 2.6 3 0 0 3 3 3 0 SusE outer membrane protein Cation_efflux PF01545.21 PVD35248.1 - 1.8e-26 93.1 9.5 2.5e-26 92.7 9.5 1.2 1 0 0 1 1 1 1 Cation efflux family WD40 PF00400.32 PVD35249.1 - 1.3e-26 92.3 26.8 2e-06 28.4 0.3 9.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD35249.1 - 1.2e-16 60.8 1.2 0.002 18.4 0.1 7.2 3 3 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD35249.1 - 0.00077 18.2 1.0 3.2 6.3 0.0 4.9 4 1 1 5 5 5 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PVD35249.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CH_2 PF06294.11 PVD35250.1 - 2.9e-29 101.0 1.3 4.2e-29 100.5 0.6 1.6 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PVD35250.1 - 8.3e-12 44.8 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain MIT_C PF16565.5 PVD35251.1 - 9.8e-56 187.6 0.8 1.8e-55 186.8 0.8 1.4 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 PVD35251.1 - 4e-17 62.0 0.7 6.9e-17 61.3 0.7 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RNase_E_G PF10150.9 PVD35251.1 - 0.0098 15.3 1.8 0.041 13.3 0.3 2.1 1 1 2 3 3 3 1 Ribonuclease E/G family Exonuc_VII_S PF02609.16 PVD35251.1 - 0.02 14.9 1.7 0.2 11.8 0.1 2.9 2 1 1 3 3 3 0 Exonuclease VII small subunit TPR_11 PF13414.6 PVD35251.1 - 0.047 13.4 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 TPR repeat Aida_N PF08910.10 PVD35251.1 - 0.13 12.6 1.4 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Aida N-terminus DUF3810 PF12725.7 PVD35251.1 - 0.54 9.6 2.3 0.64 9.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) EMC3_TMCO1 PF01956.16 PVD35251.1 - 1.1 9.0 3.0 0.36 10.5 0.4 1.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like F-box-like PF12937.7 PVD35252.1 - 4.4e-06 26.5 1.9 2.9e-05 23.9 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD35252.1 - 0.00019 21.3 0.2 0.0014 18.5 0.0 2.8 2 0 0 2 2 2 1 F-box domain BTB PF00651.31 PVD35253.1 - 7.6e-11 42.2 0.0 3.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Slx4 PF09494.10 PVD35253.1 - 1.2e-10 41.1 0.0 2.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Ras PF00071.22 PVD35254.1 - 5.8e-55 185.3 0.0 7.4e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD35254.1 - 4.5e-30 104.3 0.0 7.6e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD35254.1 - 1.4e-10 40.9 0.1 2.4e-10 40.2 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD35254.1 - 1.9e-06 27.9 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD35254.1 - 0.00039 20.3 0.1 0.003 17.5 0.2 2.1 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PVD35254.1 - 0.0026 17.3 0.0 0.0084 15.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD35254.1 - 0.0028 17.0 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PVD35254.1 - 0.004 17.4 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PVD35254.1 - 0.0079 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 PVD35254.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 PVD35254.1 - 0.018 15.4 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 PVD35254.1 - 0.05 12.8 0.9 4.7 6.3 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AIG1 PF04548.16 PVD35254.1 - 0.054 12.8 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family PduV-EutP PF10662.9 PVD35254.1 - 0.11 12.3 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 PVD35254.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 PVD35254.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Utp12 PF04003.12 PVD35255.1 - 4.5e-24 84.8 0.4 7.2e-24 84.2 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Utp21 PF04192.12 PVD35255.1 - 0.00078 19.0 0.3 0.0013 18.3 0.3 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 PVD35255.1 - 0.0008 19.7 0.0 2 8.8 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD35255.1 - 0.0016 19.2 0.1 34 5.5 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Utp13 PF08625.11 PVD35255.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain RXT2_N PF08595.11 PVD35255.1 - 0.21 11.6 4.1 0.35 10.9 4.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal WD40 PF00400.32 PVD35256.1 - 7.2e-08 33.0 8.3 0.012 16.4 0.2 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD35256.1 - 0.00019 21.7 0.0 5 7.5 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 PVD35256.1 - 0.0061 15.7 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) ATP-synt_C PF00137.21 PVD35257.1 - 3.3e-35 120.2 36.0 3.7e-22 78.4 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 PVD35257.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 DUF4149 PF13664.6 PVD35257.1 - 2.5 8.4 7.7 1.3 9.3 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) HSP90 PF00183.18 PVD35258.1 - 6.9e-104 348.6 3.9 4.8e-101 339.2 2.4 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 PVD35258.1 - 2.3e-09 37.2 0.1 5.3e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PVD35258.1 - 5.2e-07 30.2 0.2 1e-06 29.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MamL-1 PF09596.10 PVD35261.1 - 1.1e-20 73.6 7.9 1.6e-20 73.0 7.9 1.3 1 0 0 1 1 1 1 MamL-1 domain Activator_LAG-3 PF11498.8 PVD35261.1 - 0.0097 14.9 0.9 0.011 14.7 0.9 1.0 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF2407_C PF13373.6 PVD35261.1 - 0.033 14.4 0.3 0.038 14.2 0.3 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain LRR_6 PF13516.6 PVD35264.1 - 1.4e-08 34.1 6.0 0.00021 21.1 0.1 4.6 4 1 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 PVD35264.1 - 2.5e-06 27.7 1.0 0.16 12.5 0.1 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD35264.1 - 6.7e-05 22.9 2.3 5 8.1 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_2 PF07723.13 PVD35264.1 - 0.17 12.6 9.6 0.28 11.9 0.4 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat Kelch_1 PF01344.25 PVD35265.1 - 1.8e-86 283.5 12.3 4.7e-17 61.3 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD35265.1 - 3.5e-51 169.9 4.0 8.6e-09 35.4 0.1 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD35265.1 - 6.9e-31 105.0 7.5 1.1e-06 28.3 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PVD35265.1 - 2.5e-30 104.2 6.8 1.1e-05 25.4 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 PVD35265.1 - 8.3e-27 93.6 1.2 1.5e-26 92.8 1.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PVD35265.1 - 1.9e-25 88.6 14.8 0.00077 19.7 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 PVD35265.1 - 2.4e-08 34.0 0.5 1.4e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 PVD35265.1 - 0.0005 20.2 1.6 0.0011 19.1 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 PVD35265.1 - 0.001 19.0 5.6 0.49 10.4 0.1 5.4 6 0 0 6 6 6 1 Kelch motif Sarcoglycan_1 PF04790.13 PVD35266.1 - 9.4e-63 212.0 0.0 1.1e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 PVD35266.1 - 0.00016 21.6 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 PVD35266.1 - 0.12 12.2 0.1 4.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Ras PF00071.22 PVD35268.1 - 1.6e-51 174.1 0.1 2.1e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD35268.1 - 2.2e-33 115.0 0.0 3.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD35268.1 - 2.7e-17 62.7 0.1 3.4e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD35268.1 - 5.5e-09 35.7 0.1 6.9e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD35268.1 - 6.5e-08 32.3 0.5 3.9e-06 26.5 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD35268.1 - 3.2e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PVD35268.1 - 3.4e-06 26.6 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD35268.1 - 5.4e-05 22.5 1.2 0.0017 17.6 0.5 2.7 1 1 1 2 2 2 1 G-protein alpha subunit TniB PF05621.11 PVD35268.1 - 0.0056 16.1 0.0 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AMA-1 PF02430.15 PVD35268.1 - 0.029 13.3 0.1 0.039 12.9 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 PduV-EutP PF10662.9 PVD35268.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NARP1 PF12569.8 PVD35269.1 - 6.7e-194 645.6 19.4 2.9e-131 438.9 13.7 2.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 PVD35269.1 - 3.4e-15 54.9 11.6 0.0016 18.5 0.1 7.4 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35269.1 - 1.9e-12 46.9 10.1 0.19 12.6 0.1 9.7 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35269.1 - 1.8e-11 43.2 20.5 0.001 19.0 0.1 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35269.1 - 2.4e-09 37.6 13.7 0.045 14.3 0.2 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35269.1 - 2.2e-06 27.9 14.7 1.1 9.6 0.1 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35269.1 - 3.2e-06 26.7 18.1 0.0079 16.0 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD35269.1 - 1.1e-05 25.1 10.6 0.14 12.3 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 PVD35269.1 - 2.8e-05 24.3 2.9 1.4 9.8 0.3 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 PVD35269.1 - 0.00027 20.2 8.5 0.0015 17.8 1.2 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD35269.1 - 0.00069 19.7 8.4 0.33 11.1 0.4 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35269.1 - 0.00069 19.2 0.1 0.00069 19.2 0.1 4.1 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 PVD35269.1 - 0.00083 19.6 6.3 1.1 9.8 0.0 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD35269.1 - 0.0035 16.8 6.9 0.0043 16.5 0.3 3.3 3 2 1 4 4 4 1 MalT-like TPR region TPR_6 PF13174.6 PVD35269.1 - 0.0039 17.7 14.5 0.9 10.3 0.0 6.3 7 0 0 7 7 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD35269.1 - 0.0049 17.1 22.0 0.0087 16.3 0.3 6.1 5 2 2 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD35269.1 - 0.05 14.3 10.7 4.9 7.9 0.3 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 PVD35269.1 - 0.064 13.7 5.7 0.15 12.5 0.4 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 PVD35269.1 - 0.3 11.0 14.0 12 6.0 0.3 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD35269.1 - 0.96 9.6 9.4 31 4.7 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 PVD35269.1 - 2.1 8.8 7.6 12 6.4 0.1 5.2 5 0 0 5 5 5 0 PPR repeat Sec3_C PF09763.9 PVD35270.1 - 1.8e-113 380.4 21.0 2.2e-85 287.5 11.6 2.2 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 PVD35270.1 - 2.5e-20 72.4 0.6 6.6e-20 71.0 0.6 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FANCI_S4 PF14678.6 PVD35270.1 - 0.011 14.9 4.7 0.93 8.6 1.4 2.5 2 0 0 2 2 2 0 FANCI solenoid 4 DUF3416 PF11896.8 PVD35270.1 - 0.02 15.2 0.1 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) GAPES2 PF17156.4 PVD35270.1 - 0.12 12.2 0.1 9 6.0 0.1 2.4 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain DUF3573 PF12097.8 PVD35270.1 - 0.36 9.6 1.0 13 4.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) L31 PF09784.9 PVD35271.1 - 0.11 12.9 0.1 0.92 10.0 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Calreticulin PF00262.18 PVD35272.1 - 1.4e-137 458.5 16.1 1.4e-137 458.5 16.1 2.7 2 1 0 2 2 2 1 Calreticulin family MAP17 PF15807.5 PVD35272.1 - 0.013 15.8 0.4 0.044 14.0 0.4 1.9 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Connexin PF00029.19 PVD35272.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Connexin UPF0542 PF15086.6 PVD35272.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 V_ATPase_I PF01496.19 PVD35272.1 - 0.23 9.3 0.1 0.33 8.8 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 PVD35272.1 - 1.1 8.4 9.3 1.8 7.7 6.7 2.3 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Senescence PF06911.12 PVD35273.1 - 1e-39 136.7 1.9 1.8e-39 136.0 1.9 1.4 1 0 0 1 1 1 1 Senescence-associated protein MIT PF04212.18 PVD35273.1 - 1.4e-05 25.0 1.9 5.2e-05 23.2 1.9 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Inp1 PF12634.7 PVD35273.1 - 0.027 14.5 0.0 0.077 13.0 0.0 1.9 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 Pepsin-I3 PF06394.13 PVD35273.1 - 0.035 14.3 0.2 0.27 11.5 0.1 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Solute_trans_a PF03619.16 PVD35274.1 - 1.8e-11 44.1 0.6 2.6e-11 43.5 0.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4275 PF14101.6 PVD35275.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) Pou PF00157.17 PVD35276.1 - 4.8e-30 103.4 0.0 9.5e-30 102.4 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 PVD35276.1 - 1e-17 63.7 1.6 1.9e-17 62.8 1.6 1.5 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 PVD35276.1 - 0.00087 19.6 0.1 0.1 12.9 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain DUF4770 PF15994.5 PVD35276.1 - 0.019 15.2 1.2 0.037 14.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Homeobox_KN PF05920.11 PVD35276.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain LRR_8 PF13855.6 PVD35277.1 - 4e-26 90.5 41.1 2.8e-07 30.2 0.4 7.9 6 2 0 7 7 7 6 Leucine rich repeat TIR PF01582.20 PVD35277.1 - 3e-15 56.5 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD35277.1 - 8.6e-12 45.7 0.0 1.6e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD35277.1 - 2.6e-07 30.8 47.1 0.0018 18.7 0.7 8.6 5 4 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD35277.1 - 7.4e-06 25.6 15.1 0.07 12.6 0.3 4.5 2 2 2 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 PVD35277.1 - 0.013 15.5 3.3 4.7 7.2 2.4 3.4 2 2 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) TPKR_C2 PF16920.5 PVD35277.1 - 0.045 13.9 2.4 0.14 12.3 1.3 2.5 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 PVD35277.1 - 5.3 7.4 28.1 21 5.5 0.1 9.0 9 0 0 9 9 9 0 Leucine Rich repeat RRM_1 PF00076.22 PVD35278.1 - 9.3e-05 22.2 0.0 0.00045 20.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 PVD35279.1 - 3e-09 37.1 0.0 0.00061 20.0 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD35279.1 - 1.5e-05 24.1 0.0 0.061 12.3 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 PVD35279.1 - 2.5e-05 24.9 10.7 0.023 15.6 0.1 4.7 3 1 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.6 PVD35279.1 - 0.034 13.5 0.0 0.19 11.0 0.0 2.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LRR_8 PF13855.6 PVD35280.1 - 1.6e-23 82.2 14.9 6.3e-12 45.1 1.5 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD35280.1 - 5e-13 49.0 10.5 4.8e-07 30.0 0.7 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) I-set PF07679.16 PVD35280.1 - 1.2e-06 28.5 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD35280.1 - 3.8e-06 27.4 0.1 3.8e-06 27.4 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 PVD35280.1 - 2.9e-05 24.0 7.7 4.6 8.2 0.0 5.9 6 1 0 6 6 4 2 Leucine Rich Repeat ig PF00047.25 PVD35280.1 - 3e-05 24.1 4.0 0.00027 21.1 3.4 2.4 1 1 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 PVD35280.1 - 5.1e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD35280.1 - 0.00035 20.1 3.7 0.33 10.5 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Mucin PF01456.17 PVD35280.1 - 0.00075 19.5 31.2 0.00075 19.5 31.2 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Ig_2 PF13895.6 PVD35280.1 - 0.0018 18.6 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD35280.1 - 0.11 12.5 6.3 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain LRR_6 PF13516.6 PVD35280.1 - 0.74 10.0 18.8 3.4 8.0 0.1 5.0 6 0 0 6 6 6 0 Leucine Rich repeat FSA_C PF10479.9 PVD35280.1 - 2.5 6.1 15.0 3.5 5.7 15.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 PVD35280.1 - 5.3 7.2 24.4 0.42 10.8 19.2 1.8 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF4728 PF15860.5 PVD35281.1 - 0.17 12.6 1.4 0.2 12.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) MitMem_reg PF13012.6 PVD35283.1 - 3.4e-24 85.4 0.1 5.6e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PVD35283.1 - 4.5e-24 84.7 0.2 8.2e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NFRKB_winged PF14465.6 PVD35284.1 - 5.9e-36 122.8 1.5 1.8e-35 121.3 1.2 2.0 2 0 0 2 2 2 1 NFRKB Winged Helix-like DUF659 PF04937.15 PVD35285.1 - 0.087 12.7 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Exo_endo_phos_2 PF14529.6 PVD35286.1 - 4.9e-05 23.2 0.1 7.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD35288.1 - 0.00021 20.9 0.0 0.00049 19.7 0.0 1.6 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PVD35288.1 - 0.025 14.8 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain FAM176 PF14851.6 PVD35289.1 - 0.00042 20.0 1.4 0.0007 19.3 1.4 1.3 1 0 0 1 1 1 1 FAM176 family UPF0239 PF06783.11 PVD35289.1 - 0.003 17.7 0.4 0.0082 16.3 0.4 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0239) F5_F8_type_C PF00754.25 PVD35289.1 - 0.0036 17.4 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain MAP17 PF15807.5 PVD35289.1 - 0.052 13.8 0.2 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Protocadherin PF08374.11 PVD35289.1 - 0.093 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin V_ATPase_I PF01496.19 PVD35289.1 - 0.27 9.1 0.2 0.33 8.8 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 PVD35289.1 - 0.31 10.2 1.7 0.41 9.8 1.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 PVD35289.1 - 2.8 7.3 11.0 3.6 6.9 11.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 PVD35289.1 - 3.2 5.7 9.2 4.2 5.3 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Integrase_Zn PF02022.19 PVD35290.1 - 2.6e-08 33.7 19.9 94 3.1 0.0 11.8 12 0 0 12 12 12 0 Integrase Zinc binding domain DUF3673 PF12425.8 PVD35290.1 - 1.4e-07 31.3 12.3 1.4e+02 2.5 0.0 11.1 12 0 0 12 12 12 0 Protein of unknown function (DUF3673) eIF2_C PF09173.11 PVD35290.1 - 0.0025 18.0 18.2 2.6e+02 2.0 0.1 10.2 11 0 0 11 11 11 0 Initiation factor eIF2 gamma, C terminal Ig_Tie2_1 PF10430.9 PVD35290.1 - 0.0058 17.0 45.0 5.1 7.6 0.6 10.0 1 1 11 12 12 12 3 Tie-2 Ig-like domain 1 Phi-29_GP4 PF05464.11 PVD35290.1 - 0.006 16.9 29.3 1.4e+02 2.7 0.0 11.2 12 1 1 13 13 13 0 Phi-29-like late genes activator (early protein GP4) Myosin_tail_1 PF01576.19 PVD35291.1 - 8.4e-43 146.4 27.7 3.5e-32 111.2 18.7 2.0 1 1 1 2 2 2 2 Myosin tail Sec8_exocyst PF04048.14 PVD35291.1 - 0.0022 17.9 1.3 0.0043 16.9 0.7 1.8 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2524 PF10732.9 PVD35291.1 - 0.041 14.2 5.1 0.087 13.1 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HAUS-augmin3 PF14932.6 PVD35291.1 - 0.13 11.8 16.3 0.046 13.3 11.8 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 PVD35291.1 - 0.19 11.0 19.6 0.53 9.6 7.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 PVD35291.1 - 0.24 11.7 8.3 0.067 13.5 2.9 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 PVD35291.1 - 0.38 10.8 8.6 0.69 10.0 2.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 PVD35291.1 - 0.74 10.2 19.7 0.71 10.3 18.4 1.5 1 1 1 2 2 2 0 Fez1 DUF4404 PF14357.6 PVD35291.1 - 0.79 10.4 10.4 3.3 8.4 1.6 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Fib_alpha PF08702.10 PVD35291.1 - 0.98 9.6 10.1 0.31 11.2 5.7 1.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 PVD35291.1 - 1.5 8.9 6.6 0.79 9.8 3.2 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SOAR PF16533.5 PVD35291.1 - 1.5 8.8 8.7 15 5.6 6.7 3.0 2 1 0 2 2 2 0 STIM1 Orai1-activating region RSS_P20 PF11757.8 PVD35291.1 - 2.1 8.9 7.0 2.3 8.7 0.3 2.5 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain DUF724 PF05266.14 PVD35291.1 - 3.5 7.4 16.6 3.1 7.6 7.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF724) BST2 PF16716.5 PVD35291.1 - 6.3 7.5 16.6 3.6 8.2 4.4 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 fn3 PF00041.21 PVD35292.1 - 1.5e-12 47.7 0.0 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD35292.1 - 0.048 14.2 0.1 16 6.2 0.1 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain zf-C3HC4_3 PF13920.6 PVD35293.1 - 1.2e-06 28.3 10.0 1.2e-06 28.3 10.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD35293.1 - 6.8e-06 26.0 10.1 6.8e-06 26.0 10.1 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD35293.1 - 0.00032 20.5 14.8 0.00032 20.5 14.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD35293.1 - 0.0007 19.4 13.7 0.0007 19.4 13.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD35293.1 - 0.00086 19.6 14.6 0.00086 19.6 14.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PVD35293.1 - 0.0018 18.2 12.2 0.0018 18.2 12.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD35293.1 - 0.0053 16.9 14.0 0.0053 16.9 14.0 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD35293.1 - 0.011 15.6 13.3 0.011 15.6 13.3 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Plasmodium_HRP PF05403.11 PVD35294.1 - 0.0051 16.6 63.1 0.16 11.8 38.7 2.1 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) Neugrin PF06413.11 PVD35294.1 - 1.7 8.6 13.1 6.2 6.8 12.3 2.0 1 1 1 2 2 2 0 Neugrin Shikimate_dh_N PF08501.11 PVD35296.1 - 0.0032 17.7 0.0 0.018 15.3 0.0 2.3 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain RICTOR_N PF14664.6 PVD35296.1 - 0.029 13.4 0.1 0.05 12.6 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF3384 PF11864.8 PVD35296.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF4304 PF14137.6 PVD35296.1 - 0.18 11.9 0.4 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Nop14 PF04147.12 PVD35296.1 - 2.1 6.4 10.5 2.1 6.4 5.1 2.1 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.11 PVD35296.1 - 2.5 6.6 5.2 5.2 5.5 5.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 PVD35296.1 - 5.8 4.9 9.9 11 3.9 9.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 PVD35296.1 - 5.9 6.6 10.7 12 5.6 10.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 PVD35296.1 - 8 6.9 12.8 18 5.8 12.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_hydro_31 PF01055.26 PVD35297.1 - 4.7e-35 121.6 0.3 1.3e-29 103.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Smg8_Smg9 PF10220.9 PVD35298.1 - 4.1e-200 667.3 10.5 1.3e-130 437.4 4.7 2.7 1 1 1 2 2 2 2 Smg8_Smg9 Pro_isomerase PF00160.21 PVD35299.1 - 2.4e-38 131.9 0.5 1.4e-18 67.6 0.0 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FGE-sulfatase PF03781.16 PVD35300.1 - 3.9e-60 203.6 11.8 5.5e-60 203.1 11.8 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 KRTAP PF11759.8 PVD35302.1 - 0.074 13.6 12.9 0.15 12.6 12.9 1.5 1 0 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 PVD35302.1 - 0.4 10.8 12.3 0.57 10.3 11.9 1.4 1 1 0 1 1 1 0 Keratin type II head Cwf_Cwc_15 PF04889.12 PVD35304.1 - 0.00027 20.7 4.6 0.00035 20.4 4.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 PVD35304.1 - 0.056 12.0 3.9 0.063 11.9 3.9 1.1 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.12 PVD35304.1 - 0.2 11.1 3.0 0.21 11.0 3.0 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 PVD35304.1 - 0.22 10.8 13.5 0.4 10.0 13.5 1.4 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 PVD35304.1 - 0.35 10.4 3.0 0.4 10.3 3.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 PVD35304.1 - 0.49 8.5 3.0 0.51 8.5 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 PVD35304.1 - 0.69 8.4 3.0 0.73 8.3 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 PVD35304.1 - 0.86 10.6 16.0 1.5 9.9 16.0 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 PVD35304.1 - 1.6 9.0 8.2 4.5 7.6 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 PVD35304.1 - 2.8 7.9 7.0 0.81 9.7 4.2 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal SOG2 PF10428.9 PVD35305.1 - 0.31 10.2 31.1 0.47 9.6 31.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Lectin_C PF00059.21 PVD35307.1 - 1.1e-16 61.5 2.8 2.9e-16 60.1 2.8 1.8 1 0 0 1 1 1 1 Lectin C-type domain MtrB PF05440.12 PVD35307.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B MtrG PF04210.13 PVD35307.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Forkhead PF00250.18 PVD35308.1 - 3.8e-38 129.6 0.3 7.8e-38 128.6 0.1 1.6 2 0 0 2 2 2 1 Forkhead domain TPR_1 PF00515.28 PVD35309.1 - 4.4e-21 73.8 7.2 1.5e-07 30.9 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35309.1 - 6.9e-16 57.7 4.5 1.7e-05 24.4 0.0 5.6 3 2 3 6 6 6 3 TPR repeat TPR_2 PF07719.17 PVD35309.1 - 5.8e-15 54.1 12.5 0.0038 17.2 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35309.1 - 1.6e-12 46.8 3.9 0.0031 17.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35309.1 - 4.6e-12 45.7 2.5 0.0084 16.8 0.0 5.5 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35309.1 - 3.7e-11 42.3 0.7 0.0076 16.4 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35309.1 - 1.3e-09 38.4 8.1 0.012 16.1 0.4 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 PVD35309.1 - 4.9e-09 35.6 0.7 0.0017 18.2 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35309.1 - 5e-09 36.6 6.0 7.5e-05 23.3 0.2 4.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35309.1 - 1.1e-06 28.9 4.4 0.0016 18.7 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD35309.1 - 2.2e-05 24.5 0.4 0.046 13.9 0.1 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35309.1 - 0.0041 17.7 2.6 40 5.2 0.0 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD35309.1 - 0.071 13.3 1.5 15 5.9 0.3 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PVD35309.1 - 0.11 12.4 5.0 7.4 6.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD35309.1 - 3.9 7.9 8.9 62 4.0 0.2 4.6 4 2 2 6 6 6 0 Tetratricopeptide repeat DUF1713 PF08213.11 PVD35310.1 - 8.6 6.4 31.6 53 3.8 30.4 2.3 1 1 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) DFF-C PF09033.10 PVD35311.1 - 2.5e-20 73.0 1.2 3.8e-20 72.4 1.2 1.2 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.15 PVD35311.1 - 4.8e-17 61.8 1.0 1.7e-16 60.0 0.2 2.1 3 0 0 3 3 3 1 CIDE-N domain N_formyltrans_C PF18216.1 PVD35311.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain KH_1 PF00013.29 PVD35312.1 - 2.1e-201 652.1 64.8 4.5e-15 55.2 0.9 15.7 15 1 0 15 15 15 15 KH domain SLS PF14611.6 PVD35312.1 - 2.3e-19 70.1 19.1 0.0015 18.4 0.0 8.8 2 2 6 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 PVD35312.1 - 1.3e-17 63.3 41.7 0.0037 17.1 0.1 13.1 13 0 0 13 13 13 7 KH domain KH_5 PF13184.6 PVD35312.1 - 6.6e-05 22.9 31.9 0.13 12.4 0.1 11.0 12 0 0 12 12 12 2 NusA-like KH domain Bcr-Abl_Oligo PF09036.10 PVD35312.1 - 0.015 15.3 4.1 8.4 6.5 0.0 5.1 6 0 0 6 6 6 0 Bcr-Abl oncoprotein oligomerisation domain DUF1115 PF06544.12 PVD35312.1 - 0.035 14.2 0.1 2.2 8.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) YbbR PF07949.12 PVD35312.1 - 0.04 14.3 24.7 1.8 9.0 0.0 9.8 13 0 0 13 13 13 0 YbbR-like protein KH_4 PF13083.6 PVD35312.1 - 0.062 13.2 0.1 0.062 13.2 0.1 9.2 11 1 1 12 12 12 0 KH domain FtsQ PF03799.15 PVD35312.1 - 0.17 12.7 2.5 18 6.2 0.0 4.9 5 3 1 6 6 5 0 Cell division protein FtsQ EIF_2_alpha PF07541.12 PVD35312.1 - 0.3 11.2 3.0 1.2 9.3 0.2 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit SH3_15 PF18346.1 PVD35312.1 - 0.54 10.6 2.0 1.9 8.9 0.0 3.1 3 0 0 3 3 2 0 Mind bomb SH3 repeat domain AAA PF00004.29 PVD35313.1 - 5.6e-37 127.1 0.0 8.6e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD35313.1 - 6.2e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD35313.1 - 3.1e-05 24.0 0.1 0.00023 21.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PVD35313.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD35313.1 - 0.0003 21.1 0.6 0.021 15.1 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD35313.1 - 0.00066 20.1 1.0 0.0058 17.0 1.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 PVD35313.1 - 0.02 14.1 0.2 0.09 12.0 0.0 1.9 1 1 1 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 PVD35313.1 - 0.021 14.5 0.1 1.3 8.7 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 PVD35313.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PVD35313.1 - 0.034 13.5 0.2 0.13 11.7 0.2 1.8 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 PVD35313.1 - 0.1 12.0 0.0 25 4.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 PVD35313.1 - 0.13 11.8 0.3 6.7 6.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 PVD35313.1 - 0.18 12.3 0.0 0.33 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain TIM PF00121.18 PVD35314.1 - 1.2e-91 306.4 0.0 1.4e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Menin PF05053.13 PVD35315.1 - 2.4 6.4 12.3 2.6 6.3 12.3 1.0 1 0 0 1 1 1 0 Menin E1-E2_ATPase PF00122.20 PVD35316.1 - 6.7e-28 97.4 0.1 6.7e-28 97.4 0.1 3.2 5 0 0 5 5 5 1 E1-E2 ATPase P5-ATPase PF12409.8 PVD35316.1 - 8.4e-24 84.1 0.2 2.3e-23 82.6 0.2 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 PVD35316.1 - 4.6e-13 49.9 0.0 1.1e-05 25.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PVD35316.1 - 5.9e-06 25.9 0.1 3.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PVD35316.1 - 4.2e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 PVD35316.1 - 0.00099 18.9 9.3 0.00099 18.9 9.3 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus MTH865 PF07747.11 PVD35317.1 - 0.094 12.5 0.1 0.64 9.8 0.1 2.1 2 0 0 2 2 2 0 MTH865-like family Ig_3 PF13927.6 PVD35320.1 - 6.9e-186 603.4 13.2 5.5e-16 58.9 0.0 15.7 15 0 0 15 15 15 15 Immunoglobulin domain I-set PF07679.16 PVD35320.1 - 6.2e-176 571.1 0.0 2e-14 53.4 0.0 15.6 15 0 0 15 15 15 15 Immunoglobulin I-set domain Ldl_recept_a PF00057.18 PVD35320.1 - 2.2e-157 510.9 396.1 7.2e-13 48.5 9.6 20.7 22 0 0 22 22 18 18 Low-density lipoprotein receptor domain class A Ig_2 PF13895.6 PVD35320.1 - 1.3e-131 429.2 0.8 2.3e-12 47.1 0.0 15.8 15 0 0 15 15 15 15 Immunoglobulin domain ig PF00047.25 PVD35320.1 - 2.2e-114 373.9 0.0 4.1e-10 39.7 0.0 15.8 15 0 0 15 15 15 15 Immunoglobulin domain Laminin_B PF00052.18 PVD35320.1 - 3.2e-106 350.8 0.0 4.6e-36 123.7 0.0 3.4 3 0 0 3 3 3 3 Laminin B (Domain IV) Laminin_G_1 PF00054.23 PVD35320.1 - 3.8e-75 250.4 0.0 4.5e-26 91.6 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 PVD35320.1 - 2.4e-72 241.4 0.0 3e-26 92.4 0.0 3.7 3 0 0 3 3 3 3 Laminin G domain V-set PF07686.17 PVD35320.1 - 6.2e-52 174.4 35.6 0.02 15.0 0.0 24.7 16 11 8 25 25 25 14 Immunoglobulin V-set domain Laminin_EGF PF00053.24 PVD35320.1 - 6.8e-37 125.4 148.8 1.4e-10 41.1 15.5 22.5 17 4 4 21 21 15 11 Laminin EGF domain Izumo-Ig PF16706.5 PVD35320.1 - 1.8e-20 72.8 1.0 0.02 14.9 0.0 12.9 13 0 0 13 13 13 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD35320.1 - 4.1e-16 58.3 0.1 0.35 10.5 0.0 12.2 14 0 0 14 14 14 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD35320.1 - 1.4e-12 47.5 16.2 0.25 11.4 0.0 11.4 12 0 0 12 12 12 3 CD80-like C2-set immunoglobulin domain Laminin_G_3 PF13385.6 PVD35320.1 - 9.7e-08 32.3 0.0 0.21 11.7 0.0 3.5 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD35320.1 - 2.3e-06 27.8 18.3 2.7e-05 24.4 3.9 25.7 27 2 2 29 29 18 5 EGF-like domain Ig_C17orf99 PF17736.1 PVD35320.1 - 2e-05 24.5 0.0 9.7 6.3 0.0 6.6 6 1 1 7 7 7 0 C17orf99 Ig domain SEA PF01390.20 PVD35320.1 - 0.00054 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 SEA domain Receptor_2B4 PF11465.8 PVD35320.1 - 0.028 14.6 0.0 39 4.5 0.0 4.7 5 0 0 5 5 4 0 Natural killer cell receptor 2B4 DUF5335 PF17269.2 PVD35320.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) MRP-S22 PF10245.9 PVD35321.1 - 1.3e-87 293.6 0.5 1.5e-87 293.3 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 DUF1143 PF06608.11 PVD35322.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1143) cobW PF02492.19 PVD35323.1 - 3.8e-32 111.3 0.0 4.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 PVD35323.1 - 3.7e-05 22.8 0.1 0.015 14.3 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 PVD35323.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 PVD35323.1 - 0.034 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PVD35323.1 - 0.038 14.5 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 PVD35323.1 - 0.061 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 PVD35323.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PVD35323.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SelP_N PF04592.14 PVD35323.1 - 2.4 7.5 17.4 3.4 7.0 17.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2796 PF10986.8 PVD35323.1 - 7.6 6.5 24.1 13 5.7 24.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Amidohydro_1 PF01979.20 PVD35324.1 - 2.6e-67 227.6 0.6 4.3e-67 226.9 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 PVD35324.1 - 2e-52 176.6 2.5 4.3e-52 175.5 2.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 PVD35324.1 - 1.3e-35 121.6 0.1 3e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 PVD35324.1 - 2.7e-21 75.4 0.2 1.3e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 PVD35324.1 - 1.8e-06 27.7 3.6 1.6e-05 24.6 0.1 2.6 1 1 0 2 2 2 1 Amidohydrolase family SfLAP PF11139.8 PVD35325.1 - 0.0029 17.1 0.9 0.005 16.3 0.9 1.3 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein 7tm_1 PF00001.21 PVD35326.1 - 1.3e-23 83.6 13.1 7.7e-18 64.8 5.3 2.5 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD35326.1 - 0.00069 19.1 5.9 0.00069 19.1 5.9 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Synaptobrevin PF00957.21 PVD35326.1 - 0.17 11.7 2.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Synaptobrevin DUF2345 PF10106.9 PVD35327.1 - 0.0013 18.6 0.2 0.5 10.2 0.2 3.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) COX2 PF00116.20 PVD35327.1 - 2.3 8.1 11.6 37 4.2 0.3 4.3 1 1 3 4 4 4 0 Cytochrome C oxidase subunit II, periplasmic domain Pneumo_M2 PF07380.11 PVD35327.1 - 5.1 7.4 18.0 91 3.4 0.3 5.8 1 1 3 4 4 4 0 Pneumovirus M2 protein GalKase_gal_bdg PF10509.9 PVD35331.1 - 1e-22 79.4 0.1 1.8e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 PVD35331.1 - 3.5e-12 46.5 0.0 7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PVD35331.1 - 2.5e-10 40.4 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain IDEAL PF08858.10 PVD35331.1 - 0.14 11.9 0.5 27 4.6 0.0 3.3 4 0 0 4 4 4 0 IDEAL domain FHA PF00498.26 PVD35332.1 - 1.2e-10 41.6 0.3 3.3e-10 40.2 0.3 1.9 1 0 0 1 1 1 1 FHA domain Cpn10 PF00166.21 PVD35332.1 - 0.083 13.0 1.0 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit DUF4533 PF15047.6 PVD35332.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Cyt-b5 PF00173.28 PVD35333.1 - 9.6e-11 41.7 0.0 3.8e-10 39.8 0.0 2.0 2 1 1 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C14 PF00656.22 PVD35334.1 - 1.6e-42 146.2 0.3 2.2e-42 145.7 0.3 1.2 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 PVD35334.1 - 1.7e-12 47.2 0.0 4.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD35334.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Peptidase_C14 PF00656.22 PVD35335.1 - 1.4e-41 143.1 0.5 2.1e-41 142.5 0.5 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 PVD35335.1 - 2e-11 43.8 0.0 5.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD35335.1 - 0.016 15.2 0.1 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 Caspase recruitment domain Glyco_transf_92 PF01697.27 PVD35336.1 - 1.9e-14 53.9 0.7 1.2e-07 31.7 0.2 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 92 HycA_repressor PF11046.8 PVD35336.1 - 0.062 13.5 1.5 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Transcriptional repressor of hyc and hyp operons Peptidase_C78 PF07910.13 PVD35336.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C78 Glyco_hydro_9 PF00759.19 PVD35337.1 - 3.7e-136 454.8 11.4 4.9e-136 454.4 11.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 PVD35338.1 - 2.5e-12 47.0 0.1 2.5e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 PVD35339.1 - 1e-96 324.9 11.8 1.2e-96 324.6 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 PVD35340.1 - 8e-137 457.0 9.3 1e-136 456.6 9.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 S6OS1 PF15676.5 PVD35341.1 - 0.00029 19.5 24.1 0.00029 19.5 24.1 2.2 2 1 1 3 3 3 1 Six6 opposite strand transcript 1 family ArfGap PF01412.18 PVD35342.1 - 6.3e-40 135.9 0.2 1.4e-39 134.7 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 PVD35342.1 - 1.2e-25 90.6 6.2 8.4e-24 84.6 6.2 2.3 1 1 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 PVD35342.1 - 2e-20 73.1 0.8 1.3e-12 48.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 PVD35342.1 - 1.1e-17 64.4 0.4 4.5e-17 62.5 0.1 2.2 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.6 PVD35342.1 - 3e-12 46.5 0.2 1e-07 32.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35342.1 - 6.3e-10 38.4 0.2 0.12 13.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PVD35342.1 - 2.8e-09 37.3 0.0 0.0012 19.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD35342.1 - 9.1e-09 35.4 1.1 0.011 16.1 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.6 PVD35342.1 - 0.00029 21.1 0.2 0.00097 19.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PVD35342.1 - 0.0034 17.8 1.5 0.1 13.0 1.5 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain Enolase_C PF00113.22 PVD35343.1 - 4.7e-89 298.5 0.1 6.5e-89 298.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PVD35343.1 - 5.3e-28 97.8 0.6 8.5e-28 97.1 0.6 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain Peptidase_C14 PF00656.22 PVD35344.1 - 9.4e-26 91.3 2.6 4.6e-25 89.0 2.6 2.0 1 1 0 1 1 1 1 Caspase domain CARD_2 PF16739.5 PVD35344.1 - 4.8e-09 36.1 0.1 8.8e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD PF00619.21 PVD35344.1 - 4.9e-09 36.1 0.2 1.1e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CAMSAP_CKK PF08683.11 PVD35344.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Death PF00531.22 PVD35344.1 - 0.093 12.9 0.0 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 Death domain Tmem26 PF09772.9 PVD35345.1 - 9.1e-58 195.9 3.5 1.1e-57 195.6 3.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.6 PVD35345.1 - 0.019 14.8 1.6 0.019 14.8 1.6 2.2 2 0 0 2 2 2 0 CECR6/TMEM121 family MIIP PF15734.5 PVD35347.1 - 1.2e-50 173.0 9.0 1.2e-50 173.0 9.0 1.7 1 1 0 1 1 1 1 Migration and invasion-inhibitory CHDCT2 PF08074.11 PVD35348.1 - 4.9e-87 290.5 0.2 1.4e-86 289.0 0.2 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1086 PF06461.11 PVD35348.1 - 1.5e-59 199.8 0.0 5.3e-59 198.0 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 PVD35348.1 - 1.7e-58 198.0 0.0 4.7e-58 196.6 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF1087 PF06465.13 PVD35348.1 - 1.6e-27 95.3 3.5 1.6e-27 95.3 3.5 3.8 3 0 0 3 3 1 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 PVD35348.1 - 6.5e-25 86.8 0.1 1.5e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain Helicase_C PF00271.31 PVD35348.1 - 2.8e-22 79.2 0.0 5.8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 PVD35348.1 - 2e-19 69.2 33.0 8.5e-11 41.6 7.0 3.0 3 0 0 3 3 2 2 PHD-finger Chromo PF00385.24 PVD35348.1 - 5.4e-18 64.7 7.7 1e-12 47.8 0.8 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PVD35348.1 - 1.7e-08 34.7 0.0 1.7e-08 34.7 0.0 3.5 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PVD35348.1 - 3.2e-07 29.8 0.0 3.2e-07 29.8 0.0 2.9 2 1 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 HMG_box PF00505.19 PVD35348.1 - 0.00047 20.5 0.0 0.0025 18.2 0.0 2.3 1 0 0 1 1 1 1 HMG (high mobility group) box AAA_22 PF13401.6 PVD35348.1 - 0.0029 17.9 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain PHD_2 PF13831.6 PVD35348.1 - 0.23 11.0 19.0 0.082 12.5 4.2 3.1 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.6 PVD35348.1 - 1.6 8.9 15.9 1.5 9.0 2.0 2.6 1 1 0 2 2 2 0 PHD-zinc-finger like domain Resistin PF06954.11 PVD35349.1 - 0.028 15.0 0.9 0.085 13.4 0.2 2.0 2 0 0 2 2 2 0 Resistin CUB_2 PF02408.20 PVD35349.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 CUB-like domain CBM_14 PF01607.24 PVD35351.1 - 2.8e-05 24.2 27.0 0.01 16.0 9.9 2.8 2 1 1 3 3 3 2 Chitin binding Peritrophin-A domain Antistasin PF02822.14 PVD35351.1 - 0.74 10.5 10.6 10 6.9 1.0 3.2 2 1 0 2 2 2 0 Antistasin family CBM_14 PF01607.24 PVD35352.1 - 0.00031 20.8 10.4 0.00069 19.7 9.9 1.7 1 1 1 2 2 2 2 Chitin binding Peritrophin-A domain TLV_coat PF00429.19 PVD35352.1 - 9.2 4.8 6.0 9.6 4.7 6.0 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) NAD_kinase PF01513.21 PVD35354.1 - 1.6e-61 208.1 0.0 2e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 PVD35354.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PFK PF00365.20 PVD35354.1 - 0.049 13.0 0.0 9.2 5.5 0.0 2.3 2 1 0 2 2 2 0 Phosphofructokinase Proteasome PF00227.26 PVD35355.1 - 2.3e-43 147.9 1.1 2.7e-43 147.7 1.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Fig1 PF12351.8 PVD35356.1 - 0.53 10.2 3.3 3.2 7.6 3.9 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 XRN_N PF03159.18 PVD35357.1 - 9.4e-86 287.2 0.0 9.4e-86 287.2 0.0 2.0 2 0 0 2 2 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PVD35357.1 - 7.4e-76 255.9 24.2 1.8e-63 215.1 4.6 3.6 3 0 0 3 3 3 2 Xrn1 helical domain DNA_ligase_A_N PF04675.14 PVD35357.1 - 1.3e-32 113.5 2.2 1.5e-32 113.3 0.3 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 PVD35357.1 - 3.1e-28 98.8 0.7 1.8e-16 60.4 0.1 2.8 1 1 1 2 2 2 2 ATP dependent DNA ligase domain XRN1_D1 PF18332.1 PVD35357.1 - 8.3e-26 90.9 0.3 3.4e-25 88.9 0.3 2.1 1 1 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 PVD35357.1 - 8.8e-18 64.2 0.5 2.1e-17 63.0 0.2 1.9 2 0 0 2 2 1 1 Xrn1 SH3-like domain LRR_4 PF12799.7 PVD35357.1 - 4.3e-15 55.6 14.2 0.00016 22.0 1.7 5.1 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD35357.1 - 4e-13 48.9 18.1 6.7e-06 25.8 0.2 5.6 3 1 3 6 6 6 4 Leucine rich repeat LIG3_BRCT PF16759.5 PVD35357.1 - 1e-12 48.1 0.0 3.2e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain LRR_9 PF14580.6 PVD35357.1 - 1.2e-11 44.5 3.7 4.4e-09 36.1 0.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeat zf-PARP PF00645.18 PVD35357.1 - 1.3e-08 35.6 0.0 7e-08 33.2 0.0 2.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DNA_ligase_A_C PF04679.15 PVD35357.1 - 1.8e-08 34.9 0.0 8.4e-08 32.7 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-CCHH PF10283.9 PVD35357.1 - 1.3e-07 31.4 3.3 3.4e-07 30.1 3.3 1.7 1 0 0 1 1 1 1 PBZ domain LIX1 PF14954.6 PVD35357.1 - 0.00041 19.7 0.0 0.00041 19.7 0.0 2.2 2 0 0 2 2 1 1 Limb expression 1 XRN1_D2_D3 PF18334.1 PVD35357.1 - 0.0098 16.1 0.7 0.034 14.3 0.0 2.3 2 0 0 2 2 1 1 Exoribonuclease Xrn1 D2/D3 domain LRR_6 PF13516.6 PVD35357.1 - 0.028 14.5 9.5 5.5 7.3 0.9 4.7 4 0 0 4 4 4 0 Leucine Rich repeat RNA_ligase PF09414.10 PVD35357.1 - 0.081 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA ligase LRR_1 PF00560.33 PVD35357.1 - 2.3 9.1 11.7 22 6.1 0.1 5.8 6 0 0 6 6 5 0 Leucine Rich Repeat CENP-F_C_Rb_bdg PF10490.9 PVD35360.1 - 8 6.0 18.1 1.2e+02 2.2 0.1 7.6 4 2 4 10 10 10 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Hairy_orange PF07527.13 PVD35362.1 - 0.007 16.5 0.2 0.019 15.2 0.2 1.8 1 0 0 1 1 1 1 Hairy Orange DEAD PF00270.29 PVD35363.1 - 1.6e-29 102.9 0.4 2.7e-29 102.2 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD35363.1 - 1.2e-24 86.8 0.0 3.6e-24 85.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 PVD35363.1 - 0.0011 18.8 0.4 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain HLH PF00010.26 PVD35365.1 - 1.1e-15 57.3 4.5 2.7e-15 56.1 4.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 PVD35365.1 - 5e-12 45.8 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Hairy Orange CBM_14 PF01607.24 PVD35366.1 - 8.3e-09 35.5 44.6 0.0013 18.9 9.4 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Collagen PF01391.18 PVD35366.1 - 0.025 14.3 1.2 0.057 13.2 1.2 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) OTOS PF15182.6 PVD35366.1 - 0.2 11.6 2.7 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Otospiralin DUF4033 PF13225.6 PVD35366.1 - 0.5 10.4 4.4 33 4.6 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4033) CBM_14 PF01607.24 PVD35367.1 - 5.7e-34 116.1 212.4 0.0025 18.0 6.9 13.3 13 0 0 13 13 13 13 Chitin binding Peritrophin-A domain DNA_pol_A_exo1 PF01612.20 PVD35368.1 - 1.4e-17 64.0 0.1 4e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease DNA_primase_lrg PF04104.14 PVD35368.1 - 0.09 12.2 0.4 0.24 10.8 0.2 1.7 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit IncFII_repA PF02387.15 PVD35368.1 - 0.51 9.5 3.0 0.89 8.7 1.1 2.1 2 0 0 2 2 2 0 IncFII RepA protein family DNA_pol_A_exo1 PF01612.20 PVD35369.1 - 1.3e-19 70.6 0.1 2e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.20 PVD35370.1 - 1.2e-27 96.7 0.0 2.2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease FaeA PF04703.12 PVD35370.1 - 0.046 14.1 0.2 0.097 13.1 0.2 1.5 1 0 0 1 1 1 0 FaeA-like protein Shugoshin_N PF07558.11 PVD35370.1 - 0.074 12.9 0.5 0.21 11.5 0.5 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DNA_pol_A_exo1 PF01612.20 PVD35371.1 - 5.8e-32 110.8 0.2 8e-17 61.5 0.0 2.7 2 1 1 3 3 3 2 3'-5' exonuclease DUF4461 PF14688.6 PVD35371.1 - 0.047 13.5 0.3 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) ABC_tran_CTD PF16326.5 PVD35371.1 - 0.069 13.4 0.7 15 6.0 0.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain TrmB PF01978.19 PVD35371.1 - 0.14 12.0 0.0 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DNA_pol_A_exo1 PF01612.20 PVD35372.1 - 3.6e-20 72.4 0.0 8.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease NAD_binding_8 PF13450.6 PVD35372.1 - 4.9e-09 36.3 0.1 1.2e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD35372.1 - 8.1e-08 32.2 0.1 2.6e-05 24.0 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PVD35372.1 - 0.00012 21.4 0.2 0.056 12.7 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PVD35372.1 - 0.0017 17.6 1.2 0.0017 17.6 1.2 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 PVD35372.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PVD35372.1 - 0.0031 16.8 0.1 0.0062 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PVD35372.1 - 0.024 13.9 0.0 0.75 9.0 0.1 2.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase His_biosynth PF00977.21 PVD35372.1 - 0.049 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein HI0933_like PF03486.14 PVD35372.1 - 0.097 11.4 3.5 0.13 11.0 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 PVD35372.1 - 3.3 6.7 4.6 1.1 8.2 1.6 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A SNase PF00565.17 PVD35373.1 - 0.016 15.7 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal nuclease homologue MFS_1 PF07690.16 PVD35375.1 - 0.0085 15.0 3.1 0.012 14.5 3.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-FCS PF06467.14 PVD35376.1 - 0.62 10.1 1.7 6.3 6.8 0.2 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Reeler PF02014.16 PVD35378.1 - 3.4e-13 50.5 0.0 5.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DUF3915 PF13054.6 PVD35378.1 - 0.06 13.3 1.1 0.12 12.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Reeler PF02014.16 PVD35379.1 - 2.4e-20 73.6 0.1 4.2e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Reeler domain HlyD PF00529.20 PVD35379.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS DUF641 PF04859.12 PVD35380.1 - 0.00068 20.0 6.1 0.00068 20.0 6.1 7.4 1 1 7 8 8 8 1 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 PVD35380.1 - 0.0056 16.7 11.9 0.0056 16.7 11.9 7.0 2 1 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hemocyanin_M PF00372.19 PVD35380.1 - 0.0087 15.3 0.5 0.033 13.4 0.5 2.0 1 0 0 1 1 1 1 Hemocyanin, copper containing domain DUF99 PF01949.16 PVD35380.1 - 0.97 8.8 9.5 0.81 9.1 0.2 3.5 2 2 1 3 3 3 0 Protein of unknown function DUF99 Glyco_hydro_9 PF00759.19 PVD35381.1 - 2.7e-268 890.0 24.2 3.4e-131 438.5 2.9 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD35381.1 - 1.6e-15 57.2 20.5 3.3e-05 24.1 0.5 5.4 5 0 0 5 5 5 3 Cellulose binding domain Glyco_hydro_9 PF00759.19 PVD35382.1 - 1.2e-73 248.9 1.8 1.4e-73 248.7 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 PVD35383.1 - 1.9e-139 465.6 11.1 2.4e-139 465.3 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD35383.1 - 1.2e-05 25.6 3.0 4.3e-05 23.8 2.1 2.4 1 1 1 2 2 2 1 Cellulose binding domain Glyco_hydro_9 PF00759.19 PVD35384.1 - 8.7e-119 397.6 3.6 1.1e-118 397.3 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD35384.1 - 8.2e-05 22.9 0.4 8.2e-05 22.9 0.4 2.2 2 0 0 2 2 2 1 Cellulose binding domain Glyco_hydro_9 PF00759.19 PVD35385.1 - 7.7e-122 407.7 6.2 9.7e-122 407.3 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD35385.1 - 0.0016 18.7 1.7 0.0035 17.6 0.4 2.2 2 0 0 2 2 2 1 Cellulose binding domain GYF PF02213.16 PVD35386.1 - 1.7e-13 50.0 1.7 9.3e-12 44.4 0.1 2.6 2 0 0 2 2 2 2 GYF domain GYF_2 PF14237.6 PVD35386.1 - 0.0045 16.8 0.0 0.022 14.6 0.0 2.3 1 0 0 1 1 1 1 GYF domain 2 Opi1 PF08618.10 PVD35387.1 - 0.037 13.3 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DUF4559 PF15112.6 PVD35388.1 - 3.5e-14 53.2 0.9 4e-14 53.0 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) CSN7a_helixI PF18392.1 PVD35389.1 - 4.5e-16 58.5 2.3 8.6e-16 57.6 2.3 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 PVD35389.1 - 1.9e-08 34.8 0.7 8.3e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 PCI domain DUF3226 PF11536.8 PVD35389.1 - 0.086 12.5 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) RCC1 PF00415.18 PVD35390.1 - 8e-64 212.1 8.6 2.1e-16 60.3 0.0 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD35390.1 - 5.4e-37 124.9 7.5 1.8e-08 33.9 0.0 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 PVD35390.1 - 0.063 13.7 0.0 6.6 7.2 0.0 3.1 3 0 0 3 3 3 0 SUKH-3 immunity protein Sfi1 PF08457.10 PVD35392.1 - 3.5e-08 32.4 216.7 0.0034 16.0 35.7 9.1 4 2 2 6 6 6 5 Sfi1 spindle body protein CENP-M PF11111.8 PVD35394.1 - 0.14 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) HLH PF00010.26 PVD35397.1 - 3.4e-15 55.7 2.8 5.6e-15 55.0 2.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 PVD35397.1 - 3.8e-15 55.8 0.2 6.9e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 Hairy Orange Septum_form PF13845.6 PVD35397.1 - 0.08 12.5 0.5 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Septum formation Polysacc_lyase PF14099.6 PVD35398.1 - 0.00077 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase p450 PF00067.22 PVD35399.1 - 6.2e-100 335.1 0.0 1e-99 334.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol PF00940.19 PVD35400.1 - 7.9e-134 446.6 9.6 2.2e-75 254.1 0.1 2.8 3 1 1 4 4 4 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 PVD35400.1 - 4.8e-30 105.1 0.1 4.8e-30 105.1 0.1 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 PVD35400.1 - 1.8e-08 34.4 0.1 6.7e-08 32.6 0.1 2.0 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 PVD35400.1 - 2.9e-08 33.7 0.3 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 PVD35400.1 - 0.0025 17.9 0.1 0.0099 16.1 0.1 2.1 1 0 0 1 1 1 1 PPR repeat PPR_long PF17177.4 PVD35400.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP DUF5601 PF18151.1 PVD35400.1 - 0.11 12.9 0.1 0.35 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Terminase_6C PF17289.2 PVD35400.1 - 0.11 12.5 0.3 10 6.2 0.1 2.6 2 0 0 2 2 2 0 Terminase RNaseH-like domain DUF679 PF05078.12 PVD35400.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF679) ASH PF15780.5 PVD35401.1 - 9.7e-18 64.2 9.4 3.4e-07 30.4 0.2 7.0 7 0 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PVD35401.1 - 8.4e-09 35.5 0.2 0.00055 20.1 0.1 4.5 4 0 0 4 4 4 2 Flagellar-associated PapD-like DUF1573 PF07610.11 PVD35401.1 - 6e-05 23.0 0.0 2.4 8.3 0.0 5.0 5 0 0 5 5 5 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 PVD35401.1 - 0.0012 19.1 2.3 0.85 9.9 0.1 5.6 7 0 0 7 7 7 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 PVD35401.1 - 0.042 13.7 0.2 3.7 7.4 0.0 4.1 5 0 0 5 5 5 0 MSP (Major sperm protein) domain ICAT PF06384.11 PVD35402.1 - 3.5e-21 75.2 0.1 9.6e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 PVD35402.1 - 0.00022 20.9 0.7 0.00041 20.0 0.5 1.5 1 1 0 1 1 1 1 CAMP factor (Cfa) Peptidase_S46 PF10459.9 PVD35402.1 - 0.034 12.8 3.5 0.038 12.6 3.5 1.0 1 0 0 1 1 1 0 Peptidase S46 CK2S PF15011.6 PVD35402.1 - 0.038 13.9 3.8 0.88 9.4 1.8 2.6 1 1 1 2 2 2 0 Casein Kinase 2 substrate CREPT PF16566.5 PVD35402.1 - 0.044 14.0 2.1 0.082 13.1 1.5 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2357 PF09823.9 PVD35402.1 - 0.087 12.1 1.6 0.15 11.3 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2357) DUF4143 PF13635.6 PVD35402.1 - 0.087 13.0 0.1 0.11 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4143) FlxA PF14282.6 PVD35402.1 - 0.25 11.4 9.9 0.079 13.0 5.6 2.3 2 0 0 2 2 2 0 FlxA-like protein HD_4 PF13328.6 PVD35402.1 - 0.58 9.9 2.9 1.4 8.7 2.9 1.8 1 1 0 1 1 1 0 HD domain Synaptobrevin PF00957.21 PVD35402.1 - 0.7 9.7 0.0 0.7 9.7 0.0 2.8 3 1 0 3 3 3 0 Synaptobrevin TMCO5 PF14992.6 PVD35402.1 - 0.74 9.3 8.7 5.6 6.5 9.1 1.8 1 1 1 2 2 2 0 TMCO5 family DUF883 PF05957.13 PVD35402.1 - 2.2 8.9 7.6 2.3 8.9 1.2 3.1 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) IATP PF04568.12 PVD35402.1 - 3.2 8.2 8.7 8.3 6.9 2.6 3.0 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF2408 PF10303.9 PVD35402.1 - 5.3 7.6 8.6 5.6 7.5 6.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) YtxH PF12732.7 PVD35402.1 - 6.3 7.4 6.9 13 6.5 3.8 2.4 2 1 0 2 2 2 0 YtxH-like protein AA_permease_2 PF13520.6 PVD35405.1 - 3.2e-35 121.8 33.5 4e-24 85.2 13.8 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 PVD35405.1 - 4.5e-34 117.9 31.2 8.4e-34 117.0 31.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 PVD35406.1 - 7.6e-15 54.7 7.4 7.6e-15 54.7 7.4 1.9 2 0 0 2 2 2 1 C-terminus of AA_permease DUF1440 PF07274.12 PVD35406.1 - 0.044 14.1 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) PTN13_u3 PF16599.5 PVD35406.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ WWE PF02825.20 PVD35407.1 - 2e-08 34.7 3.7 0.00052 20.6 0.9 3.0 2 0 0 2 2 2 2 WWE domain PARP PF00644.20 PVD35407.1 - 6.3e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf_CCCH_4 PF18345.1 PVD35407.1 - 0.00011 22.1 7.9 0.00033 20.6 0.1 3.6 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 PVD35407.1 - 0.013 15.4 1.4 0.013 15.4 1.4 3.9 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PVD35407.1 - 0.025 15.3 15.1 1.1 9.9 0.1 3.9 2 1 1 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 PVD35407.1 - 4.6 7.2 11.3 0.088 12.6 0.5 3.0 3 0 0 3 3 3 0 CCCH-type zinc finger UQ_con PF00179.26 PVD35408.1 - 3.9e-19 68.7 0.0 6.1e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2570 PF10828.8 PVD35408.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Prok-E2_B PF14461.6 PVD35408.1 - 0.045 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family B Sec62 PF03839.16 PVD35409.1 - 6.3e-58 195.8 8.5 6.3e-58 195.8 8.5 2.4 1 1 1 2 2 2 1 Translocation protein Sec62 DUF2207 PF09972.9 PVD35409.1 - 0.0019 17.0 1.8 0.0019 17.0 1.8 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DEP PF00610.21 PVD35409.1 - 0.013 15.5 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Neur_chan_memb PF02932.16 PVD35409.1 - 0.27 11.2 4.8 1.7 8.6 1.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3413 PF11893.8 PVD35409.1 - 4.2 6.5 5.9 7.4 5.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Guanylate_cyc PF00211.20 PVD35410.1 - 6e-48 162.9 0.0 1.3e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 PVD35410.1 - 6e-11 43.2 0.1 1.1e-10 42.5 0.1 1.4 1 0 0 1 1 1 1 Nitrate and nitrite sensing PRIMA1 PF16101.5 PVD35410.1 - 0.13 12.3 7.0 0.33 11.0 7.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 PVD35410.1 - 0.2 11.3 5.9 0.32 10.6 5.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 PVD35410.1 - 0.26 10.7 5.1 0.52 9.7 5.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD35410.1 - 0.44 10.6 5.0 0.84 9.7 5.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Glyco_hydro_31 PF01055.26 PVD35411.1 - 2.7e-54 185.0 0.1 1.4e-53 182.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Raffinose_syn PF05691.12 PVD35411.1 - 0.0023 15.8 0.0 0.0032 15.3 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 PVD35412.1 - 9.7e-53 179.9 2.3 4.4e-51 174.4 2.3 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Raffinose_syn PF05691.12 PVD35412.1 - 0.073 10.8 0.1 0.39 8.4 0.0 1.8 2 0 0 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 Sugar_tr PF00083.24 PVD35413.1 - 1.2e-24 87.0 9.2 3.5e-23 82.2 5.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD35413.1 - 6.5e-14 51.6 17.0 2.6e-12 46.4 16.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD35414.1 - 2.7e-12 46.3 21.9 5.4e-09 35.4 2.7 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PVD35414.1 - 1.1e-09 37.6 34.9 7.7e-07 28.4 9.2 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 PVD35416.1 - 3.4e-54 182.9 0.0 4.6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD35416.1 - 2.2e-30 105.1 0.0 2.6e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PVD35416.1 - 0.0022 18.2 0.0 0.0072 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 PVD35416.1 - 0.0049 17.2 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 PVD35416.1 - 0.31 11.9 1.0 1.7 9.5 1.0 2.0 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 PVD35417.1 - 8.9e-21 74.0 0.0 1.5e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD35417.1 - 1.3e-14 54.0 0.0 2e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 PVD35418.1 - 4.8e-53 179.2 0.0 6.7e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD35418.1 - 1.5e-27 95.9 0.0 2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PVD35418.1 - 0.00035 20.8 0.0 0.00082 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PVD35418.1 - 0.00063 19.8 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PVD35418.1 - 0.009 15.6 0.1 0.02 14.5 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 PVD35418.1 - 0.026 15.1 1.1 0.22 12.1 0.6 2.8 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PVD35419.1 - 1.2e-53 181.1 0.0 2.4e-53 180.2 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD35419.1 - 4.4e-25 87.9 0.1 5.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 PVD35419.1 - 1.8e-06 28.1 1.2 1.8e-06 28.1 1.2 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 PVD35419.1 - 0.00051 19.4 0.4 0.019 14.3 0.0 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 PVD35419.1 - 0.0006 19.4 0.6 0.0029 17.2 0.3 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 PVD35419.1 - 0.0036 17.5 2.0 0.0088 16.2 0.5 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PVD35419.1 - 0.84 10.3 5.3 0.36 11.4 2.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent wnt PF00110.19 PVD35421.1 - 4.9e-43 147.9 9.7 7e-42 144.1 9.7 2.0 1 1 0 1 1 1 1 wnt family wnt PF00110.19 PVD35422.1 - 2.8e-47 161.8 12.7 3.1e-47 161.7 12.7 1.1 1 0 0 1 1 1 1 wnt family SAM_1 PF00536.30 PVD35423.1 - 8.8e-20 70.9 0.0 4e-11 43.2 0.0 2.7 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD35423.1 - 4.1e-18 65.2 0.0 8.7e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PDEase_I_N PF08499.12 PVD35423.1 - 0.24 11.3 0.7 20 5.1 0.5 2.6 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Chitin_synth_2 PF03142.15 PVD35424.1 - 7.5e-33 113.9 7.4 1.8e-30 106.1 1.4 2.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD35424.1 - 8.2e-18 65.0 3.7 8.2e-18 65.0 3.7 1.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD35424.1 - 4.6e-11 43.0 0.2 7.7e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PVD35424.1 - 3.7e-08 33.0 0.1 1.5e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 PVD35424.1 - 2.5e-06 27.4 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4350 PF14258.6 PVD35424.1 - 0.053 13.9 0.2 5.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) DUF3327 PF11806.8 PVD35424.1 - 0.15 12.7 0.1 0.27 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Ilm1 PF10311.9 PVD35425.1 - 0.018 14.7 0.3 0.025 14.2 0.3 1.2 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF4175 PF13779.6 PVD35425.1 - 0.059 11.3 0.8 0.079 10.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAM_1 PF00536.30 PVD35427.1 - 1.5e-17 63.8 1.0 2.8e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Chitin_synth_2 PF03142.15 PVD35427.1 - 1.7e-17 63.2 14.5 1.2e-16 60.4 4.2 4.2 3 1 1 4 4 4 2 Chitin synthase SAM_2 PF07647.17 PVD35427.1 - 8.6e-12 45.0 0.8 2.2e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Glyco_tranf_2_3 PF13641.6 PVD35427.1 - 2e-07 31.2 0.4 6.6e-07 29.4 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PVD35427.1 - 2.4e-07 30.9 8.2 2.4e-07 30.9 8.2 4.2 3 2 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 PVD35427.1 - 0.015 14.7 0.2 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 PVD35427.1 - 0.16 11.8 0.3 0.44 10.3 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 ATP-synt_8 PF00895.20 PVD35427.1 - 0.87 10.1 0.0 0.87 10.1 0.0 5.3 7 0 0 7 7 7 0 ATP synthase protein 8 AA_permease PF00324.21 PVD35428.1 - 3.2e-36 124.9 14.9 4e-36 124.6 14.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PVD35428.1 - 9.3e-32 110.4 16.2 1.1e-31 110.1 16.2 1.0 1 0 0 1 1 1 1 Amino acid permease PRA1 PF03208.19 PVD35428.1 - 0.21 11.2 6.0 0.1 12.2 1.1 2.6 2 1 0 2 2 2 0 PRA1 family protein PH PF00169.29 PVD35429.1 - 2.8e-08 34.2 0.3 8.1e-08 32.7 0.3 1.8 1 0 0 1 1 1 1 PH domain Erf4 PF10256.9 PVD35429.1 - 0.011 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ZZ PF00569.17 PVD35429.1 - 0.042 13.7 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type PH_11 PF15413.6 PVD35429.1 - 1 9.8 3.6 80 3.7 3.6 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain Ank_2 PF12796.7 PVD35432.1 - 9.1e-27 93.5 15.2 1.1e-11 45.1 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35432.1 - 2.5e-22 78.9 3.5 2.9e-06 27.7 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35432.1 - 5.4e-19 66.3 8.7 1.4e-05 25.1 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 PVD35432.1 - 1.4e-17 63.5 10.0 2.9e-06 27.4 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD35432.1 - 9e-17 60.7 10.3 0.00013 22.2 0.1 7.6 7 0 0 7 7 7 2 Ankyrin repeat SH3_15 PF18346.1 PVD35432.1 - 1.1e-12 48.0 0.0 1.1e-06 28.8 0.0 2.9 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 PVD35432.1 - 4.9e-07 29.5 8.0 4.9e-07 29.5 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD35432.1 - 0.00011 22.0 8.3 0.00011 22.0 8.3 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Ank_2 PF12796.7 PVD35433.1 - 3.1e-48 162.3 22.7 8.2e-12 45.6 0.2 5.9 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35433.1 - 1.4e-34 118.0 7.7 1.4e-08 35.1 0.0 7.9 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35433.1 - 1.7e-33 114.2 9.6 2.6e-09 37.2 0.1 7.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD35433.1 - 2.7e-28 97.2 18.1 2.8e-05 24.4 0.0 9.0 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 PVD35433.1 - 2e-22 76.9 12.4 0.00011 22.4 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat SH3_15 PF18346.1 PVD35433.1 - 1.9e-14 53.7 0.3 1e-09 38.5 0.3 2.5 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 PVD35433.1 - 7.1e-05 22.6 9.3 7.1e-05 22.6 9.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD35433.1 - 0.0095 15.8 9.7 0.022 14.6 9.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DJ-1_PfpI PF01965.24 PVD35434.1 - 2.8e-51 173.6 0.1 3.2e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Ank_4 PF13637.6 PVD35435.1 - 3.7e-38 129.4 11.7 9.2e-08 32.5 0.1 8.3 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35435.1 - 1.6e-36 124.7 0.8 2.5e-14 53.6 0.2 4.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD35435.1 - 6.3e-36 121.3 9.4 1.3e-06 28.6 0.1 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 PVD35435.1 - 2.3e-29 101.1 8.2 2.3e-07 31.0 0.1 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35435.1 - 2.2e-28 95.1 17.5 9.3e-06 25.6 0.1 9.4 10 0 0 10 10 10 5 Ankyrin repeat SOCS_box PF07525.16 PVD35435.1 - 1.6e-07 31.6 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SOCS box UDPG_MGDP_dh_C PF03720.15 PVD35435.1 - 0.012 16.0 0.1 21 5.6 0.0 4.8 4 2 1 5 5 5 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Ank_2 PF12796.7 PVD35436.1 - 2.8e-24 85.5 1.1 8.6e-12 45.5 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD35436.1 - 9.2e-20 70.5 3.9 5.1e-05 23.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35436.1 - 1.3e-18 65.1 5.6 0.0029 18.0 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PVD35436.1 - 2.7e-17 62.4 7.0 0.00082 19.7 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 PVD35436.1 - 6.2e-16 58.6 1.3 9.2e-07 29.3 0.1 3.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Mito_carr PF00153.27 PVD35437.1 - 9.2e-63 208.2 4.7 1.4e-21 76.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3BGR PF04908.15 PVD35438.1 - 1.3e-19 70.2 0.1 1.4e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 PVD35438.1 - 2.9e-07 30.6 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin LOR PF04525.12 PVD35439.1 - 0.044 13.4 0.3 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 LURP-one-related RVT_1 PF00078.27 PVD35440.1 - 7.4e-06 25.6 0.0 2.1e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vitellogenin_N PF01347.22 PVD35441.1 - 6e-21 74.5 1.0 7e-21 74.3 1.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 PVD35441.1 - 3.1e-14 52.9 0.0 3.9e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Glyco_transf_11 PF01531.16 PVD35442.1 - 1.8e-26 93.1 0.2 2.7e-26 92.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD35442.1 - 6.5e-06 26.1 1.2 1.8e-05 24.6 1.2 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase 7TM_GPCR_Sru PF10322.9 PVD35443.1 - 9.5e-05 21.9 7.8 0.038 13.3 0.0 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Sru 7tm_1 PF00001.21 PVD35443.1 - 0.00088 18.7 14.6 0.0015 17.9 14.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD35444.1 - 2 7.6 17.8 4 6.7 17.8 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD35445.1 - 0.0048 16.2 22.6 0.0082 15.5 22.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3099 PF11298.8 PVD35445.1 - 4.3 7.5 11.4 0.45 10.7 4.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) 7TM_GPCR_Srw PF10324.9 PVD35446.1 - 1.1e-06 28.2 13.5 1.3e-06 27.9 5.3 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD35446.1 - 0.27 10.6 17.8 1.2 8.4 17.9 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Vitellogenin_N PF01347.22 PVD35448.1 - 6.7e-26 90.9 0.0 2.7e-18 65.8 0.0 2.1 1 1 1 2 2 2 2 Lipoprotein amino terminal region FliO PF04347.13 PVD35449.1 - 0.19 12.1 0.0 0.4 11.0 0.0 1.6 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO VWC PF00093.18 PVD35450.1 - 6.1e-30 103.3 77.4 1.1e-10 41.7 12.0 4.5 4 0 0 4 4 4 4 von Willebrand factor type C domain CHRD PF07452.12 PVD35450.1 - 1.2e-17 64.9 0.0 1.5e-07 32.4 0.1 4.5 4 0 0 4 4 4 4 CHRD domain Rad50_zn_hook PF04423.14 PVD35450.1 - 1.2 9.1 13.9 0.045 13.6 4.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif TPR_2 PF07719.17 PVD35451.1 - 1.8e-14 52.6 0.0 0.0014 18.6 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35451.1 - 2.6e-12 46.0 0.0 0.00023 20.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35451.1 - 1.1e-08 34.6 0.0 0.01 16.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35451.1 - 5.6e-08 32.6 0.8 0.0085 16.4 0.1 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35451.1 - 5.2e-07 29.9 0.0 0.0096 16.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35451.1 - 7.7e-07 29.5 0.3 0.00034 21.1 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35451.1 - 9.8e-07 29.1 0.0 0.074 13.9 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35451.1 - 5.1e-06 26.1 0.0 0.0005 19.7 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 PVD35451.1 - 6.4e-05 22.7 0.0 1.3 9.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD35451.1 - 0.001 19.3 0.2 0.0024 18.1 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MAS20 PF02064.15 PVD35451.1 - 0.0023 18.1 0.0 0.24 11.5 0.0 2.6 1 1 0 2 2 2 1 MAS20 protein import receptor TPR_16 PF13432.6 PVD35451.1 - 0.0027 18.3 0.0 0.019 15.6 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD35451.1 - 0.012 15.7 0.2 2.9 8.1 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF554 PF04474.12 PVD35451.1 - 0.037 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) DUF627 PF04781.12 PVD35451.1 - 0.066 13.2 0.0 0.44 10.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF627) TFIID_30kDa PF03540.13 PVD35452.1 - 3e-27 94.3 0.1 1e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 PVD35452.1 - 0.0042 17.1 0.0 0.048 13.7 0.0 2.3 1 1 0 1 1 1 1 Bromodomain associated TAF4 PF05236.14 PVD35452.1 - 0.075 12.8 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family 7tm_1 PF00001.21 PVD35453.1 - 1.8e-33 116.0 16.6 2.4e-33 115.6 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD35453.1 - 0.0016 18.2 4.8 0.1 12.3 1.8 3.1 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD35453.1 - 0.002 17.8 3.6 0.002 17.8 3.6 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 PVD35453.1 - 0.31 11.1 7.0 1 9.5 0.8 3.1 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term MFS_1 PF07690.16 PVD35454.1 - 1.5e-60 205.0 20.9 6.3e-55 186.5 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD35454.1 - 4.4e-11 42.3 28.8 8.9e-09 34.7 20.1 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 PVD35454.1 - 3.3e-07 29.2 18.2 0.0034 16.0 1.9 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_4 PF06779.14 PVD35454.1 - 1.7e-05 24.3 2.3 1.7e-05 24.3 2.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Dishevelled PF02377.15 PVD35455.1 - 1.1e-24 87.7 24.0 3.8e-24 86.0 10.0 4.2 3 2 2 5 5 5 2 Dishevelled specific domain PDZ PF00595.24 PVD35455.1 - 1e-19 70.6 1.1 2.2e-19 69.6 1.1 1.6 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 PVD35455.1 - 1.1e-15 57.5 0.0 2.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dsh_C PF12316.8 PVD35455.1 - 5.2e-09 36.8 32.3 5.2e-09 36.8 32.3 4.2 2 1 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal PDZ_6 PF17820.1 PVD35455.1 - 2.6e-06 27.2 0.1 4.7e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain DIX PF00778.17 PVD35455.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 DIX domain PDZ_2 PF13180.6 PVD35455.1 - 0.001 19.3 0.2 0.002 18.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain R3H PF01424.22 PVD35456.1 - 1.1e-15 57.3 0.1 5e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 R3H domain CENP-H PF05837.12 PVD35456.1 - 4.6 7.7 10.8 0.45 10.9 3.5 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF4207 PF13904.6 PVD35456.1 - 4.7 6.8 15.0 7 6.3 14.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) NDUF_B5 PF09781.9 PVD35457.1 - 2.4e-54 183.8 0.2 2.7e-54 183.6 0.2 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Man-6-P_recep PF02157.15 PVD35458.1 - 4.8e-83 278.1 0.1 6.1e-83 277.8 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 PVD35458.1 - 1.2e-12 48.2 0.1 1.6e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 dNK PF01712.19 PVD35459.1 - 1.2e-45 155.9 0.2 1.5e-45 155.6 0.2 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 PVD35459.1 - 3.2e-08 34.2 0.0 6.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD35459.1 - 1.4e-05 25.2 0.0 4.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PVD35459.1 - 0.00067 20.1 0.0 0.0058 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 PVD35459.1 - 0.0067 16.1 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Ploopntkinase1 PF18748.1 PVD35459.1 - 0.0068 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase1 HGTP_anticodon2 PF12745.7 PVD35459.1 - 0.016 14.7 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Herpes_TK PF00693.18 PVD35459.1 - 0.025 13.8 0.0 0.25 10.5 0.0 2.0 1 1 1 2 2 2 0 Thymidine kinase from herpesvirus TsaE PF02367.17 PVD35459.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PVD35459.1 - 0.031 14.5 0.0 0.063 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PVD35459.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 PVD35459.1 - 0.059 13.1 0.0 0.088 12.5 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 PVD35459.1 - 0.21 11.2 0.0 0.43 10.2 0.0 1.5 2 0 0 2 2 2 0 Dephospho-CoA kinase Man-6-P_recep PF02157.15 PVD35460.1 - 1.2e-24 86.8 0.1 1.3e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Ras PF00071.22 PVD35461.1 - 1.3e-08 34.6 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD35461.1 - 4.4e-05 23.7 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PVD35461.1 - 0.0016 17.8 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_7 PF12775.7 PVD35461.1 - 0.0032 17.0 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 PVD35461.1 - 0.0072 16.4 0.2 0.01 15.9 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PVD35461.1 - 0.013 16.0 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 PVD35461.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 PVD35461.1 - 0.03 14.0 0.3 0.05 13.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 PVD35461.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 PVD35461.1 - 0.041 13.5 0.4 0.057 13.0 0.4 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 PVD35461.1 - 0.043 14.2 0.0 0.051 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PVD35461.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 PVD35461.1 - 0.078 13.0 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arf PF00025.21 PVD35461.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 PVD35461.1 - 0.18 12.2 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD35461.1 - 0.29 11.4 0.9 0.5 10.6 0.9 1.6 1 1 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 PVD35462.1 - 1.3e-107 360.5 17.8 1.4e-107 360.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD35462.1 - 5e-20 71.7 23.5 5e-20 71.7 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily RNA_pol_Rpb4 PF03874.16 PVD35463.1 - 1.8e-25 89.6 3.3 2.2e-25 89.4 3.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pes-10 PF07149.11 PVD35463.1 - 0.012 14.7 1.2 0.014 14.5 1.2 1.0 1 0 0 1 1 1 0 Pes-10 Ldl_recept_a PF00057.18 PVD35464.1 - 0.1 12.8 0.5 0.1 12.8 0.5 2.1 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A RVT_1 PF00078.27 PVD35465.1 - 8.6e-06 25.4 0.1 1.7e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_a PF00057.18 PVD35466.1 - 4e-17 62.1 30.3 4.2e-06 26.9 1.7 5.2 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 PVD35466.1 - 4.9 6.9 21.4 1.7 8.4 0.3 3.0 3 0 0 3 3 3 0 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 PVD35467.1 - 2.4e-14 53.3 36.7 5.7e-05 23.2 0.5 4.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD35467.1 - 1.8e-07 30.8 2.7 3.9e-07 29.7 2.7 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD35467.1 - 1.5e-06 28.4 7.3 8.3e-06 26.1 0.9 2.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD35467.1 - 0.0011 19.2 3.9 1.7 9.5 0.2 4.1 3 1 0 3 3 3 2 Leucine Rich Repeat RACo_linker PF17650.1 PVD35467.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RACo linker region PRKCSH-like PF12999.7 PVD35467.1 - 0.88 9.3 18.2 2.2 8.1 0.1 3.1 3 0 0 3 3 3 0 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 PVD35468.1 - 4.6e-19 68.3 28.0 2.8e-06 27.4 3.5 5.1 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD35468.1 - 1.1e-07 31.5 1.6 2.9e-07 30.2 1.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PVD35468.1 - 6.9e-06 26.3 6.9 1.7e-05 25.1 1.2 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD35468.1 - 0.0043 17.4 5.2 2.8 8.8 0.1 4.2 3 0 0 3 3 3 2 Leucine Rich Repeat Fmp27 PF10344.9 PVD35468.1 - 0.093 10.8 2.7 0.11 10.6 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 BBL5 PF07289.11 PVD35468.1 - 0.13 11.2 1.3 0.17 10.9 1.3 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein eIF_4EBP PF05456.11 PVD35468.1 - 0.32 10.9 2.6 0.55 10.2 2.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RNA_pol_3_Rpc31 PF11705.8 PVD35468.1 - 0.72 10.1 17.3 1 9.5 17.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Saw1 PF11561.8 PVD35468.1 - 1.6 8.2 5.8 2.2 7.7 5.8 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Astro_capsid_p PF12226.8 PVD35468.1 - 2.1 7.4 8.7 3.3 6.8 8.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Paf1 PF03985.13 PVD35468.1 - 2.2 7.2 21.0 2.8 6.8 21.0 1.1 1 0 0 1 1 1 0 Paf1 CPSF100_C PF13299.6 PVD35468.1 - 3.2 7.9 8.0 4.5 7.4 8.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Usp PF00582.26 PVD35468.1 - 4.1 7.9 9.5 2.7 8.5 7.0 1.8 2 0 0 2 2 2 0 Universal stress protein family DUF913 PF06025.12 PVD35468.1 - 4.3 6.2 6.0 5.7 5.8 6.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ldl_recept_a PF00057.18 PVD35469.1 - 5.8e-17 61.6 26.9 2.1e-05 24.6 0.6 5.0 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD35469.1 - 4.1e-08 33.5 0.0 8.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 CUB domain LRR_4 PF12799.7 PVD35469.1 - 0.00037 20.8 1.1 0.0011 19.3 1.1 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD35469.1 - 0.012 15.4 0.6 0.03 14.1 0.6 1.7 1 0 0 1 1 1 0 Leucine rich repeat Ldl_recept_a PF00057.18 PVD35470.1 - 4.3e-06 26.8 12.5 0.00019 21.6 1.7 2.5 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A RACo_linker PF17650.1 PVD35470.1 - 0.045 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 RACo linker region Ldl_recept_a PF00057.18 PVD35471.1 - 3.9e-09 36.6 9.5 1.1e-06 28.8 0.3 2.8 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A RACo_linker PF17650.1 PVD35471.1 - 0.031 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 RACo linker region Ldl_recept_a PF00057.18 PVD35472.1 - 6.6e-19 67.8 34.4 1.9e-07 31.2 3.0 4.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A RACo_linker PF17650.1 PVD35472.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 RACo linker region Ldl_recept_a PF00057.18 PVD35473.1 - 4.7e-17 61.9 24.9 7.7e-05 22.8 0.4 4.8 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.20 PVD35473.1 - 6.4e-08 32.9 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 PVD35474.1 - 4.1e-16 58.9 28.8 1.5e-05 25.1 0.7 4.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD35475.1 - 9.7e-09 35.3 18.5 1.9e-05 24.8 0.9 2.9 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A LRR_4 PF12799.7 PVD35475.1 - 0.00041 20.7 3.1 0.0094 16.3 2.8 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) PRKCSH-like PF12999.7 PVD35475.1 - 1.4 8.7 8.6 0.33 10.7 4.9 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 PVD35476.1 - 2.6e-19 69.1 24.5 1.8e-05 24.8 0.4 4.8 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A RACo_linker PF17650.1 PVD35476.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RACo linker region Ldl_recept_a PF00057.18 PVD35477.1 - 2.6e-17 62.8 31.2 1.6e-05 25.0 0.9 4.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD35478.1 - 0.11 12.8 0.5 0.27 11.5 0.5 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A RNB PF00773.19 PVD35479.1 - 4.6e-88 295.7 0.2 1.8e-87 293.7 0.2 2.0 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PVD35479.1 - 6.8e-27 93.3 0.0 2e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PVD35479.1 - 2.5e-14 53.2 0.0 8.3e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 PVD35479.1 - 2.7e-13 50.0 0.1 2.7e-13 50.0 0.1 2.5 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CN_hydrolase PF00795.22 PVD35480.1 - 2e-15 56.9 0.0 2.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.21 PVD35481.1 - 4.4e-06 26.2 6.5 5.4e-06 25.9 6.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CbiQ PF02361.16 PVD35481.1 - 1.3 8.6 12.4 0.11 12.1 6.7 1.9 2 0 0 2 2 2 0 Cobalt transport protein DUF643 PF04867.12 PVD35482.1 - 0.0078 16.8 8.2 0.18 12.5 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF643) Chlorosome_CsmC PF11098.8 PVD35482.1 - 0.075 13.0 5.6 0.22 11.5 5.6 1.7 1 0 0 1 1 1 0 Chlorosome envelope protein C Apolipo_F PF15148.6 PVD35482.1 - 0.49 9.9 2.5 5.1 6.6 1.7 2.4 1 1 0 1 1 1 0 Apolipoprotein F DUF883 PF05957.13 PVD35482.1 - 3.7 8.2 9.2 0.33 11.6 0.8 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) FragX_IP PF05994.11 PVD35482.1 - 6.6 4.6 9.5 3.9 5.4 1.9 2.1 2 0 0 2 2 2 0 Cytoplasmic Fragile-X interacting family Lectin_C PF00059.21 PVD35483.1 - 2.3e-06 28.3 0.3 9.9e-06 26.3 0.0 2.1 1 1 1 2 2 2 1 Lectin C-type domain NECFESHC PF16621.5 PVD35483.1 - 0.18 11.8 3.2 0.51 10.4 3.2 1.8 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 MASE2 PF05230.11 PVD35483.1 - 0.47 10.5 2.3 0.91 9.6 2.3 1.4 1 0 0 1 1 1 0 MASE2 domain Guanylate_cyc PF00211.20 PVD35484.1 - 1.2e-51 175.0 0.0 2.1e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 PVD35484.1 - 8.8e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 PVD35484.1 - 0.0033 16.9 0.3 0.0065 15.9 0.3 1.5 1 0 0 1 1 1 1 Heme NO binding associated CPDase PF07823.11 PVD35484.1 - 0.05 13.3 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Calici_PP_N PF08405.11 PVD35484.1 - 0.072 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Viral polyprotein N-terminal NIT PF08376.10 PVD35485.1 - 3.6e-23 83.2 0.0 4.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Nitrate and nitrite sensing Acyl_transf_3 PF01757.22 PVD35486.1 - 4.1e-23 82.0 42.8 5.5e-23 81.6 42.8 1.1 1 0 0 1 1 1 1 Acyltransferase family WAP PF00095.21 PVD35487.1 - 3.1e-05 24.3 11.5 9e-05 22.8 11.5 1.8 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Death PF00531.22 PVD35488.1 - 6.2e-07 29.5 0.0 1.5e-06 28.2 0.0 1.7 2 0 0 2 2 1 1 Death domain CYYR1 PF10873.8 PVD35488.1 - 0.00019 21.9 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 TNFR_c6 PF00020.18 PVD35488.1 - 0.00049 20.4 3.8 0.00049 20.4 3.8 2.9 2 0 0 2 2 2 1 TNFR/NGFR cysteine-rich region Shisa PF13908.6 PVD35488.1 - 0.00086 19.6 1.6 0.0017 18.7 1.6 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 PVD35488.1 - 0.0012 18.6 0.1 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 PVD35488.1 - 0.0016 18.3 0.2 0.0031 17.4 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_C_2 PF16492.5 PVD35488.1 - 0.0024 18.6 0.1 0.0062 17.3 0.1 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 PVD35488.1 - 0.0025 18.7 1.3 0.0036 18.1 0.1 1.9 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 PVD35488.1 - 0.0031 16.4 1.4 0.0031 16.4 1.4 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 PVD35488.1 - 0.0075 16.4 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Podoplanin Protocadherin PF08374.11 PVD35488.1 - 0.0077 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Protocadherin RCR PF12273.8 PVD35488.1 - 0.021 15.5 0.0 0.045 14.4 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RIFIN PF02009.16 PVD35488.1 - 0.031 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Rifin ODV-E18 PF10717.9 PVD35488.1 - 0.038 13.9 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Hum_adeno_E3A PF05393.11 PVD35488.1 - 0.046 13.7 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein PARM PF17061.5 PVD35488.1 - 0.051 13.7 0.5 0.081 13.1 0.1 1.6 2 0 0 2 2 1 0 PARM Adeno_E3_CR2 PF02439.15 PVD35488.1 - 0.051 13.3 2.7 0.091 12.5 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 PVD35488.1 - 0.089 13.4 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Baculo_11_kDa PF06143.11 PVD35488.1 - 0.12 12.0 0.4 0.28 10.8 0.4 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family HEAT_2 PF13646.6 PVD35488.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats FAM176 PF14851.6 PVD35488.1 - 0.16 11.6 0.2 0.16 11.6 0.2 2.7 2 1 1 3 3 3 0 FAM176 family Mid2 PF04478.12 PVD35488.1 - 0.2 11.5 1.9 0.18 11.6 0.3 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Reeler PF02014.16 PVD35489.1 - 7.3e-10 39.7 0.1 7.3e-10 39.7 0.1 1.9 2 0 0 2 2 2 1 Reeler domain 7tm_1 PF00001.21 PVD35490.1 - 1.4e-46 159.0 0.1 1.6e-46 158.8 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD35490.1 - 5.8e-09 36.0 14.6 1.1e-08 35.1 14.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD35490.1 - 2.7e-06 27.3 5.0 3.7e-06 26.9 5.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD35490.1 - 0.00017 21.1 8.1 0.00024 20.5 8.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 PVD35490.1 - 0.0039 17.0 9.5 0.0055 16.5 9.5 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Mito_carr PF00153.27 PVD35491.1 - 6.4e-30 102.9 4.9 8.2e-17 60.9 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Sulfatase PF00884.23 PVD35492.1 - 7.6e-21 74.8 0.1 2.4e-13 50.2 0.0 3.5 2 1 1 3 3 3 2 Sulfatase Sulfatase PF00884.23 PVD35493.1 - 1.9e-56 191.8 0.2 2.8e-56 191.2 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD35493.1 - 9.1e-05 22.2 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Ank PF00023.30 PVD35494.1 - 8.2e-31 105.1 13.4 5.3e-07 29.8 0.1 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 PVD35494.1 - 3.5e-29 97.6 10.8 0.0012 19.1 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_2 PF12796.7 PVD35494.1 - 7.6e-29 100.1 10.8 3.2e-11 43.6 2.4 4.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35494.1 - 1.1e-26 92.8 6.5 2e-06 28.2 0.3 6.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35494.1 - 2.3e-24 85.2 11.7 8.2e-05 22.8 0.2 5.9 3 2 1 5 5 5 5 Ankyrin repeats (many copies) SH3_15 PF18346.1 PVD35494.1 - 1.6e-12 47.5 0.7 1.7e-07 31.5 0.1 3.5 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain DOG1 PF14144.6 PVD35494.1 - 0.0061 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Seed dormancy control MazE_antitoxin PF04014.18 PVD35494.1 - 0.039 13.9 1.7 0.77 9.8 0.2 2.6 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Ank_2 PF12796.7 PVD35495.1 - 3.6e-28 98.0 10.8 4.7e-07 30.3 0.2 5.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD35495.1 - 1.1e-27 95.7 13.6 1.6e-07 31.4 0.2 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD35495.1 - 7e-25 87.1 12.2 1.8e-06 28.4 0.0 7.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 PVD35495.1 - 7.7e-23 79.9 17.9 0.0018 18.6 0.1 7.7 7 0 0 7 7 7 6 Ankyrin repeat SH3_15 PF18346.1 PVD35495.1 - 8e-22 77.3 0.4 3.1e-11 43.4 0.0 3.2 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_3 PF13606.6 PVD35495.1 - 3e-18 64.0 16.3 0.048 14.2 0.2 8.2 8 0 0 8 8 8 6 Ankyrin repeat SH3_15 PF18346.1 PVD35496.1 - 1.1e-21 76.9 0.1 1.4e-11 44.5 0.0 2.8 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 PVD35496.1 - 5.3e-20 71.8 2.1 5.9e-08 33.2 0.1 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35496.1 - 1.3e-17 63.9 5.7 0.00016 22.2 0.0 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35496.1 - 1.7e-17 63.2 2.1 4.1e-05 23.8 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD35496.1 - 8.3e-16 57.6 4.2 6.5e-05 23.2 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 PVD35496.1 - 8e-12 44.3 1.3 0.098 13.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat ZZ PF00569.17 PVD35496.1 - 8.8 6.2 23.4 3.3 7.6 18.2 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Ank PF00023.30 PVD35497.1 - 6.3e-24 83.3 13.3 5.7e-05 23.4 0.3 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PVD35497.1 - 2.3e-22 79.0 2.1 8e-10 39.1 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35497.1 - 3.2e-21 75.7 8.4 1.8e-09 38.0 0.6 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) SH3_15 PF18346.1 PVD35497.1 - 6.5e-20 71.2 0.5 2.9e-11 43.5 0.1 2.7 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_5 PF13857.6 PVD35497.1 - 1.9e-18 66.3 4.6 8.1e-06 26.0 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35497.1 - 3.4e-15 54.6 8.5 0.00023 21.3 0.2 7.3 8 0 0 8 8 8 3 Ankyrin repeat ZZ PF00569.17 PVD35497.1 - 1.9 8.3 19.3 3.8 7.4 19.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Ank_4 PF13637.6 PVD35498.1 - 5.7e-24 84.2 5.8 2.4e-09 37.6 0.1 5.5 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35498.1 - 4.4e-21 74.7 0.4 7.4e-09 35.7 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35498.1 - 1.4e-20 73.7 3.5 6.2e-09 36.3 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD35498.1 - 8.5e-20 68.8 0.5 0.00013 22.1 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PVD35498.1 - 1.2e-19 69.8 3.5 6e-05 23.3 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat SH3_15 PF18346.1 PVD35498.1 - 1.2e-19 70.4 0.6 1.4e-12 47.7 0.4 2.5 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 PVD35498.1 - 6.3e-06 26.0 9.0 1.1e-05 25.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD35498.1 - 0.00056 19.7 11.9 0.0054 16.6 9.9 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD35498.1 - 0.31 11.4 13.0 0.23 11.8 10.9 2.0 2 0 0 2 2 2 0 Ring finger domain Ank_2 PF12796.7 PVD35499.1 - 3.4e-18 66.0 0.1 3.8e-08 33.8 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35499.1 - 1.7e-16 60.4 1.3 0.00095 19.7 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD35499.1 - 7.6e-15 54.6 2.7 0.0014 18.9 1.8 6.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD35499.1 - 2.2e-14 53.3 1.1 2.9e-07 30.6 0.3 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35499.1 - 1.2e-11 43.7 1.5 0.0023 18.3 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 PVD35499.1 - 1.1e-06 28.4 9.1 2e-06 27.6 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD35499.1 - 0.00024 20.9 10.3 0.00074 19.3 10.4 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Fer2 PF00111.27 PVD35499.1 - 0.85 9.6 7.1 1.9 8.5 6.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Zn_ribbon_SprT PF17283.2 PVD35499.1 - 6.5 6.8 9.4 2.6 8.0 6.3 1.9 1 1 1 2 2 2 0 SprT-like zinc ribbon domain SH3_15 PF18346.1 PVD35500.1 - 6.6e-31 106.4 0.0 8e-12 45.3 0.0 4.4 4 0 0 4 4 4 3 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 PVD35500.1 - 7.4e-06 25.7 13.0 7.4e-06 25.7 13.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 PVD35500.1 - 0.0038 17.8 0.0 0.14 12.8 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35500.1 - 0.035 14.7 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD35500.1 - 0.069 13.7 0.1 3.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Rubella_Capsid PF05750.11 PVD35500.1 - 0.07 12.7 4.3 0.13 11.8 4.3 1.3 1 0 0 1 1 1 0 Rubella capsid protein Rhodanese_C PF12368.8 PVD35500.1 - 0.39 11.1 7.4 0.24 11.8 4.7 2.0 2 0 0 2 2 2 0 Rhodanase C-terminal VIR_N PF15912.5 PVD35500.1 - 2 7.9 8.8 3.4 7.2 8.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Ank_4 PF13637.6 PVD35501.1 - 6.1e-07 29.9 0.0 0.0065 17.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 PVD35501.1 - 1.2e-06 28.2 13.4 1.2e-06 28.2 13.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 PVD35501.1 - 4.7e-05 23.6 0.0 0.13 12.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PVD35501.1 - 0.0005 20.4 0.0 0.012 16.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 PVD35501.1 - 0.0032 18.0 0.0 0.0069 17.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Rhodanese_C PF12368.8 PVD35501.1 - 0.023 15.1 3.5 0.023 15.1 3.5 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal Prok-RING_4 PF14447.6 PVD35501.1 - 0.039 13.8 15.4 0.089 12.7 15.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TMEM154 PF15102.6 PVD35502.1 - 0.00066 19.6 0.0 0.00066 19.6 0.0 3.6 3 1 0 4 4 4 1 TMEM154 protein family ig PF00047.25 PVD35502.1 - 0.0016 18.6 1.5 0.0041 17.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain TMEM52 PF14979.6 PVD35502.1 - 0.085 12.8 0.1 0.085 12.8 0.1 2.4 1 1 1 2 2 2 0 Transmembrane 52 Pheromone PF08015.11 PVD35503.1 - 6.5 7.9 48.2 7.3e+02 1.3 11.9 8.0 1 1 2 3 3 3 0 Fungal mating-type pheromone Macro PF01661.21 PVD35504.1 - 1.5e-12 47.6 0.0 3.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Macro domain YqaJ PF09588.10 PVD35504.1 - 2.5e-05 24.4 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain GTF2I PF02946.14 PVD35505.1 - 2.4e-17 62.8 0.2 1.6e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 GTF2I-like repeat DUF4371 PF14291.6 PVD35505.1 - 2.1e-06 27.5 1.7 2.6e-06 27.3 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4371) Mob1_phocein PF03637.17 PVD35505.1 - 0.0026 17.8 0.0 0.67 10.0 0.0 3.2 2 1 1 3 3 3 1 Mob1/phocein family WXG100 PF06013.12 PVD35505.1 - 0.044 14.0 1.9 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Med9 PF07544.13 PVD35505.1 - 0.14 12.3 2.1 10 6.3 0.1 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FmiP_Thoc5 PF09766.9 PVD35505.1 - 0.14 11.4 4.1 0.99 8.6 0.1 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Sec2p PF06428.11 PVD35505.1 - 0.27 11.2 3.6 7.5 6.6 0.7 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FlgN PF05130.12 PVD35505.1 - 0.3 11.6 5.3 9.5 6.7 1.4 2.8 2 0 0 2 2 2 0 FlgN protein NYD-SP28 PF14772.6 PVD35505.1 - 2 8.5 6.5 20 5.3 0.1 3.2 3 0 0 3 3 3 0 Sperm tail BTB_2 PF02214.22 PVD35506.1 - 2.3e-08 34.2 0.0 6.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain CI-B14_5a PF07347.12 PVD35506.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) BTB_3 PF16017.5 PVD35506.1 - 0.055 13.6 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Ion_trans PF00520.31 PVD35507.1 - 3.7e-25 88.6 6.1 5e-25 88.1 6.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD35507.1 - 1.6e-14 53.6 7.3 3.3e-14 52.6 7.3 1.6 1 0 0 1 1 1 1 Ion channel DUF4730 PF15873.5 PVD35507.1 - 0.52 10.6 3.8 14 6.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) Ion_trans PF00520.31 PVD35508.1 - 2.5e-21 76.0 16.8 4.9e-21 75.1 16.0 1.8 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD35508.1 - 8.9e-14 51.2 6.1 8.9e-14 51.2 6.1 3.6 3 1 0 3 3 3 1 Ion channel BTB_2 PF02214.22 PVD35508.1 - 1.1e-11 44.9 0.0 2.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF5305 PF17231.2 PVD35508.1 - 0.021 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) An_peroxidase PF03098.15 PVD35509.1 - 4.8e-117 391.7 1.0 1.4e-105 353.9 0.1 2.9 2 1 0 2 2 2 2 Animal haem peroxidase DNA_pol3_delta2 PF13177.6 PVD35509.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Hanta_G2 PF01561.16 PVD35509.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 FHA PF00498.26 PVD35510.1 - 6.2e-13 48.9 0.0 1.7e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD35510.1 - 2.6e-06 27.7 0.0 1.4e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SlyX PF04102.12 PVD35510.1 - 0.017 15.7 1.8 0.017 15.7 1.8 16.2 11 6 6 17 17 17 0 SlyX MALT1_Ig PF18703.1 PVD35510.1 - 0.017 15.2 0.0 0.91 9.5 0.0 3.6 2 0 0 2 2 2 0 MALT1 Ig-like domain DUF3800 PF12686.7 PVD35510.1 - 0.031 14.9 0.0 22 5.7 0.0 4.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF356 PF04009.12 PVD35510.1 - 0.11 12.7 1.8 0.61 10.4 1.8 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) KH_5 PF13184.6 PVD35510.1 - 0.23 11.6 2.0 0.56 10.3 0.1 2.7 2 1 1 3 3 3 0 NusA-like KH domain Globin PF00042.22 PVD35511.1 - 1.5e-10 41.6 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Globin Antimicrobial21 PF14861.6 PVD35511.1 - 5.1 6.9 9.1 6 6.7 0.0 2.8 3 0 0 3 3 3 0 Plant antimicrobial peptide AA_permease_2 PF13520.6 PVD35512.1 - 3.1e-37 128.4 34.4 3.1e-37 128.4 34.4 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 PVD35512.1 - 1.3e-30 106.4 36.8 1.3e-30 106.4 36.8 1.7 2 0 0 2 2 2 1 Amino acid permease MOZART1 PF12554.8 PVD35512.1 - 0.092 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated CENP-U PF13097.6 PVD35512.1 - 8.1 6.4 8.4 0.44 10.5 1.3 2.0 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Got1 PF04178.12 PVD35513.1 - 7e-38 129.5 16.7 1.2e-37 128.8 16.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.16 PVD35513.1 - 0.0002 20.4 11.3 0.00023 20.2 11.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CSG2 PF16965.5 PVD35513.1 - 0.025 13.6 3.4 0.033 13.1 3.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EcsB PF05975.12 PVD35513.1 - 0.035 12.9 11.0 0.043 12.7 11.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB 6PGD PF00393.19 PVD35514.1 - 3.7e-128 426.9 0.0 5.4e-128 426.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PVD35514.1 - 2.4e-50 170.8 0.0 3.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PVD35514.1 - 0.0024 18.4 0.1 0.0048 17.4 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 PVD35514.1 - 0.0033 17.5 0.2 0.008 16.2 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 PVD35514.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 PVD35514.1 - 0.046 13.3 0.2 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HHH_9 PF17674.1 PVD35514.1 - 0.093 13.6 0.0 0.38 11.7 0.0 2.0 2 0 0 2 2 2 0 HHH domain Ub-Mut7C PF14451.6 PVD35514.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin ApbA PF02558.16 PVD35514.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Neuralized PF07177.12 PVD35515.1 - 5e-11 42.8 0.0 9.5e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Neuralized zf-C3HC4 PF00097.25 PVD35516.1 - 1.5e-06 27.9 15.0 4e-06 26.6 15.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD35516.1 - 2.9e-05 24.0 12.3 2.9e-05 24.0 12.3 2.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD35516.1 - 3.3e-05 23.6 18.9 6.6e-05 22.7 18.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD35516.1 - 0.0062 16.7 20.0 0.0062 16.7 20.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PVD35516.1 - 0.016 14.9 11.6 0.76 9.6 8.6 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 PVD35516.1 - 0.043 13.8 20.6 0.043 13.8 20.6 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD35516.1 - 0.15 11.9 22.3 0.42 10.5 22.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD35516.1 - 1.4 9.3 23.3 0.21 12.0 18.6 2.1 2 1 0 2 2 2 0 Ring finger domain CBM_14 PF01607.24 PVD35517.1 - 2.1e-14 53.4 5.7 3.9e-14 52.5 5.7 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CENP-B_dimeris PF09026.10 PVD35517.1 - 2 8.9 7.5 3.7 8.0 7.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Elong_Iki1 PF10483.9 PVD35518.1 - 1.7e-14 54.0 1.1 4.5e-07 29.7 0.1 2.4 1 1 1 2 2 2 2 Elongator subunit Iki1 CBM_14 PF01607.24 PVD35518.1 - 0.0009 19.4 2.7 0.0019 18.4 2.7 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain K_channel_TID PF07941.11 PVD35518.1 - 0.05 14.1 1.3 0.12 12.8 1.3 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Spt46 PF17734.1 PVD35519.1 - 0.082 12.7 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 Arm-DNA-bind_4 PF14657.6 PVD35520.1 - 3.4 7.5 32.0 74 3.2 0.1 10.6 2 2 12 15 15 15 0 Arm DNA-binding domain Spc7 PF08317.11 PVD35521.1 - 0.00013 21.0 22.2 0.0002 20.4 22.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein ERM PF00769.19 PVD35521.1 - 0.00025 21.0 18.4 0.00044 20.2 18.4 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YabA PF06156.13 PVD35521.1 - 0.0017 18.9 21.1 0.012 16.2 6.5 2.9 1 1 1 2 2 2 1 Initiation control protein YabA TSC22 PF01166.18 PVD35521.1 - 0.01 16.1 2.0 0.01 16.1 2.0 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 PVD35521.1 - 0.023 14.8 29.4 0.087 12.9 15.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 PVD35521.1 - 0.047 13.3 26.8 0.019 14.5 21.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein DivIC PF04977.15 PVD35521.1 - 0.17 11.7 28.2 1.1 9.1 7.5 3.3 1 1 2 3 3 3 0 Septum formation initiator Rootletin PF15035.6 PVD35521.1 - 0.38 10.7 28.9 0.36 10.8 13.7 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 PVD35521.1 - 0.47 10.7 35.9 0.39 10.9 17.7 2.7 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 PVD35521.1 - 0.55 10.0 19.4 0.67 9.7 11.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 PVD35521.1 - 0.61 10.6 29.2 0.043 14.3 9.8 3.0 1 1 1 2 2 2 0 Cell division protein ZapB GAS PF13851.6 PVD35521.1 - 0.7 9.2 30.4 6.6 6.0 11.6 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 PVD35521.1 - 0.98 7.9 6.8 1.4 7.4 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_TACC PF12709.7 PVD35521.1 - 1 9.9 17.1 4.4 7.8 5.4 3.0 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 PVD35521.1 - 1.1 8.5 28.7 0.79 9.0 14.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 PVD35521.1 - 1.1 9.7 28.5 11 6.4 15.0 2.5 1 1 1 2 2 2 0 Fez1 BicD PF09730.9 PVD35521.1 - 2.1 6.7 28.4 0.12 10.7 11.6 2.2 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D IFP_35_N PF07334.13 PVD35521.1 - 7.3 6.7 17.8 8.2 6.6 3.8 4.3 3 1 1 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HALZ PF02183.18 PVD35521.1 - 7.3 6.9 17.0 5 7.4 2.1 3.4 3 1 0 3 3 3 0 Homeobox associated leucine zipper Spc24 PF08286.11 PVD35521.1 - 7.8 6.8 25.4 27 5.1 8.4 3.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 PVD35521.1 - 8.2 6.9 29.8 0.42 11.0 7.7 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) CUB PF00431.20 PVD35522.1 - 6.7e-08 32.8 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 CUB domain RACo_linker PF17650.1 PVD35522.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 RACo linker region Ldl_recept_a PF00057.18 PVD35522.1 - 0.54 10.5 3.3 0.24 11.7 0.5 1.9 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A PARP PF00644.20 PVD35523.1 - 5.3e-24 84.9 0.0 5.7e-23 81.5 0.0 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LSPR PF06049.12 PVD35523.1 - 3.9e-09 35.0 101.4 1.9 8.7 0.8 14.8 15 0 0 15 15 15 12 Coagulation Factor V LSPD Repeat WWE PF02825.20 PVD35523.1 - 0.0016 19.0 1.3 0.0034 17.9 1.3 1.6 1 0 0 1 1 1 1 WWE domain zf_CCCH_4 PF18345.1 PVD35523.1 - 0.29 11.2 27.5 2.2 8.4 1.0 4.8 4 0 0 4 4 4 0 Zinc finger domain Hep_core_N PF08290.11 PVD35523.1 - 0.33 11.0 2.8 1.3 9.1 2.8 2.0 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Torus PF16131.5 PVD35523.1 - 1.1 10.0 23.8 1.2 9.8 2.5 4.4 4 0 0 4 4 4 0 Torus domain PIP49_N PF14875.6 PVD35523.1 - 8.3 6.2 20.9 2.8 7.8 1.4 3.3 3 0 0 3 3 3 0 N-term cysteine-rich ER, FAM69 Torus PF16131.5 PVD35524.1 - 1.7 9.3 40.3 0.98 10.1 2.6 5.2 5 0 0 5 5 5 0 Torus domain PARP PF00644.20 PVD35525.1 - 1.1e-24 87.1 0.1 9.3e-24 84.1 0.1 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 PVD35526.1 - 1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35526.1 - 7.4e-05 23.3 4.1 0.00028 21.4 3.1 2.3 2 0 0 2 2 2 1 WWE domain PARP PF00644.20 PVD35527.1 - 2.6e-25 89.2 0.0 2e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35527.1 - 0.0015 19.1 0.5 0.0038 17.8 0.5 1.7 1 0 0 1 1 1 1 WWE domain SeqA_N PF17206.3 PVD35527.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain PARP PF00644.20 PVD35528.1 - 2.4e-22 79.5 0.0 1.8e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35528.1 - 2.9e-05 24.6 0.0 0.067 13.8 0.2 2.7 2 0 0 2 2 2 2 WWE domain Torus PF16131.5 PVD35528.1 - 0.015 16.0 26.7 0.061 14.0 2.5 5.4 5 0 0 5 5 5 0 Torus domain zf_CCCH_4 PF18345.1 PVD35528.1 - 0.35 11.0 34.0 0.053 13.6 2.5 6.2 6 0 0 6 6 6 0 Zinc finger domain Torus PF16131.5 PVD35530.1 - 0.0024 18.5 14.3 0.54 11.0 4.0 3.9 3 0 0 3 3 3 2 Torus domain PARP PF00644.20 PVD35531.1 - 6.2e-23 81.4 0.1 2.7e-22 79.3 0.1 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35531.1 - 0.0024 18.4 0.6 0.018 15.6 0.5 2.3 2 0 0 2 2 2 1 WWE domain Torus PF16131.5 PVD35531.1 - 4.3 8.1 27.3 1.2 9.9 2.1 4.5 4 0 0 4 4 4 0 Torus domain PARP PF00644.20 PVD35532.1 - 1.9e-23 83.1 0.0 4e-22 78.8 0.0 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCCH_4 PF18044.1 PVD35532.1 - 3e-05 23.7 5.3 3e-05 23.7 5.3 4.2 4 0 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD35532.1 - 0.00018 21.5 6.6 0.00018 21.5 6.6 4.9 5 0 0 5 5 5 1 Zinc finger domain Torus PF16131.5 PVD35532.1 - 0.0013 19.4 2.9 0.0013 19.4 2.9 5.4 6 0 0 6 6 6 2 Torus domain PARP PF00644.20 PVD35533.1 - 2.6e-19 69.6 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 PVD35534.1 - 5.6e-23 81.6 0.0 4.5e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35534.1 - 0.0048 17.5 0.5 0.012 16.2 0.1 1.9 2 0 0 2 2 2 1 WWE domain DUF1180 PF06679.12 PVD35534.1 - 0.59 10.5 2.4 1.3 9.4 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PARP PF00644.20 PVD35535.1 - 2.9e-13 49.8 0.2 2e-12 47.1 0.2 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35535.1 - 0.00028 21.4 0.2 0.0016 19.0 0.1 2.2 2 0 0 2 2 2 1 WWE domain Phage_H_T_join PF05521.11 PVD35536.1 - 0.077 13.5 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage head-tail joining protein zf-CCCH_4 PF18044.1 PVD35537.1 - 0.011 15.5 6.2 0.011 15.5 6.2 4.8 4 1 1 5 5 5 0 CCCH-type zinc finger Torus PF16131.5 PVD35537.1 - 6.5 7.5 32.6 0.14 12.8 4.2 5.2 5 0 0 5 5 5 0 Torus domain PARP PF00644.20 PVD35538.1 - 1.6e-11 44.2 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PCC_BT PF18140.1 PVD35539.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 1 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain DUF108 PF01958.18 PVD35539.1 - 0.17 12.3 0.0 2.1 8.8 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function DUF108 PARP PF00644.20 PVD35540.1 - 8.8e-26 90.7 0.1 1.1e-24 87.2 0.1 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35540.1 - 0.0021 18.6 1.1 0.0069 17.0 0.8 2.1 2 0 0 2 2 2 1 WWE domain RRM_2 PF04059.12 PVD35540.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 zf_CCCH_4 PF18345.1 PVD35540.1 - 0.34 11.0 2.8 0.97 9.6 2.8 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 PVD35540.1 - 0.41 10.5 3.9 1.2 9.0 3.9 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger PARP PF00644.20 PVD35541.1 - 6.6e-06 25.8 0.0 8.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35541.1 - 0.13 12.9 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 WWE domain PARP PF00644.20 PVD35542.1 - 9e-28 97.2 0.2 4.3e-24 85.2 0.0 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35542.1 - 5.3e-05 23.7 2.3 0.00072 20.1 0.9 2.6 2 0 0 2 2 2 1 WWE domain zf-CCCH PF00642.24 PVD35542.1 - 0.054 13.4 7.9 0.17 11.8 0.2 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 PVD35542.1 - 0.43 10.4 5.7 1.1 9.0 0.7 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_4 PF18044.1 PVD35542.1 - 1.8 8.4 14.9 0.16 11.8 2.4 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 PVD35542.1 - 3.8 8.2 6.4 38 5.0 0.0 4.0 4 0 0 4 4 4 0 Torus domain PARP PF00644.20 PVD35543.1 - 1.6e-16 60.5 0.2 1.2e-15 57.6 0.2 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Torus PF16131.5 PVD35543.1 - 1.2e-06 29.1 9.2 0.0035 18.0 1.5 4.0 3 0 0 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 PVD35543.1 - 1.1e-05 25.3 15.4 8e-05 22.6 3.1 4.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 PVD35543.1 - 0.00013 21.7 3.1 0.00013 21.7 3.1 3.5 3 0 0 3 3 3 1 CCCH-type zinc finger WWE PF02825.20 PVD35543.1 - 0.0028 18.2 5.6 0.14 12.8 3.7 2.5 2 0 0 2 2 2 1 WWE domain Myb_DNA-bind_5 PF13873.6 PVD35544.1 - 6.2e-13 48.6 7.1 1.1e-12 47.8 7.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PVD35544.1 - 5.3e-07 29.9 2.0 1.2e-06 28.8 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD35544.1 - 0.019 15.2 0.5 0.036 14.4 0.5 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PARP PF00644.20 PVD35545.1 - 3.5e-24 85.5 0.0 3.1e-23 82.4 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 PVD35545.1 - 4.9e-05 23.8 1.2 0.034 14.7 0.9 2.6 2 0 0 2 2 2 2 WWE domain Torus PF16131.5 PVD35545.1 - 0.0012 19.5 30.8 0.0026 18.4 1.3 5.6 5 0 0 5 5 5 2 Torus domain PARP PF00644.20 PVD35547.1 - 8.5e-24 84.2 0.1 7.4e-23 81.2 0.1 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Torus PF16131.5 PVD35547.1 - 0.0021 18.7 1.3 0.0021 18.7 1.3 3.0 3 0 0 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 PVD35547.1 - 0.024 14.7 1.4 0.024 14.7 1.4 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_4 PF18044.1 PVD35547.1 - 0.034 13.9 9.4 0.21 11.4 1.4 3.4 3 0 0 3 3 3 0 CCCH-type zinc finger WWE PF02825.20 PVD35547.1 - 0.051 14.2 1.8 0.19 12.4 1.7 2.0 2 0 0 2 2 2 0 WWE domain zf-CCCH_3 PF15663.5 PVD35547.1 - 0.08 13.2 6.7 4.4 7.6 1.4 4.0 4 0 0 4 4 4 0 Zinc-finger containing family zf-C3H1 PF10650.9 PVD35548.1 - 0.43 10.3 4.4 0.14 12.0 1.1 1.9 2 0 0 2 2 2 0 Putative zinc-finger domain Torus PF16131.5 PVD35548.1 - 1.8 9.3 5.3 0.62 10.8 2.3 1.8 1 1 1 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 PVD35548.1 - 4.8 7.4 10.1 0.47 10.6 2.2 2.9 3 0 0 3 3 3 0 Zinc finger domain PARP PF00644.20 PVD35549.1 - 3.3e-08 33.3 0.4 8.3e-07 28.8 0.4 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pox_F12L PF03337.13 PVD35549.1 - 0.071 11.3 0.0 0.086 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein Glyco_hydro_9 PF00759.19 PVD35551.1 - 0 1491.5 57.5 1.4e-122 410.1 10.7 6.2 4 2 2 6 6 6 6 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD35551.1 - 2.1e-12 47.2 9.5 2.9e-07 30.7 0.5 4.7 4 1 0 4 4 4 3 Cellulose binding domain Glyco_hydro_127 PF07944.12 PVD35551.1 - 0.0012 17.5 0.3 1.8 6.9 0.0 3.2 3 0 0 3 3 3 2 Beta-L-arabinofuranosidase, GH127 Prok-E2_B PF14461.6 PVD35551.1 - 0.0072 16.0 0.0 20 4.9 0.0 4.0 4 0 0 4 4 4 1 Prokaryotic E2 family B UQ_con PF00179.26 PVD35551.1 - 0.018 14.7 0.1 44 3.7 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-conjugating enzyme SopD PF11047.8 PVD35551.1 - 0.023 13.9 0.0 10 5.2 0.0 3.4 4 0 0 4 4 4 0 Salmonella outer protein D RED_N PF07808.13 PVD35551.1 - 0.1 12.2 0.1 33 3.9 0.0 3.6 4 0 0 4 4 4 0 RED-like protein N-terminal region MFS_1 PF07690.16 PVD35552.1 - 1.6e-33 116.1 23.3 9.2e-32 110.3 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD35552.1 - 2.9e-07 29.7 10.4 2.9e-07 29.7 10.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 PVD35552.1 - 0.00028 19.3 1.4 0.00028 19.3 1.4 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_3 PF16083.5 PVD35552.1 - 1.6 8.9 6.0 10 6.3 0.0 4.2 2 1 2 4 4 4 0 LydA holin phage, holin superfamily III MBOAT PF03062.19 PVD35553.1 - 2.7e-40 138.8 11.8 1.2e-39 136.6 11.8 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family YqcI_YcgG PF08892.11 PVD35553.1 - 9.4e-05 22.3 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 YqcI/YcgG family TRP_2 PF08344.11 PVD35554.1 - 7.1e-20 71.0 0.5 1.5e-19 70.0 0.5 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 PVD35554.1 - 1.6e-18 66.9 16.4 1e-17 64.2 16.4 2.0 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 PVD35554.1 - 2.8e-07 30.9 0.0 0.00042 20.8 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35554.1 - 5.8e-07 30.0 0.1 6.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PKD_channel PF08016.12 PVD35554.1 - 6.1e-06 25.2 10.2 0.0074 15.0 2.5 2.4 2 0 0 2 2 2 2 Polycystin cation channel Ank_5 PF13857.6 PVD35554.1 - 7.2e-05 23.0 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35554.1 - 0.00059 20.1 0.8 0.66 10.7 0.0 4.6 5 0 0 5 5 3 1 Ankyrin repeat GCN5L1 PF06320.13 PVD35554.1 - 0.03 14.5 1.5 0.089 12.9 1.5 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) YjbH PF06082.11 PVD35554.1 - 0.033 13.0 2.0 0.05 12.4 2.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF2532 PF10811.8 PVD35554.1 - 0.037 14.1 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Mod_r PF07200.13 PVD35554.1 - 0.08 13.1 4.8 1 9.4 1.0 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 PVD35554.1 - 3.5 7.7 4.8 1.4 8.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 PVD35554.1 - 9.5 5.7 7.4 19 4.7 7.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TRP_2 PF08344.11 PVD35555.1 - 1.7e-13 50.6 0.0 3.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 PVD35555.1 - 2.2e-09 36.9 14.4 1.7e-08 34.0 14.4 2.1 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 PVD35555.1 - 5.1e-09 36.6 0.1 0.00015 22.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35555.1 - 2.2e-07 31.3 0.0 0.00033 21.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35555.1 - 5.2e-05 23.4 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35555.1 - 0.00034 20.8 0.1 0.53 11.0 0.0 4.1 4 0 0 4 4 3 1 Ankyrin repeat PKD_channel PF08016.12 PVD35555.1 - 0.009 14.7 1.0 0.009 14.7 1.0 2.2 2 0 0 2 2 2 1 Polycystin cation channel DUF2532 PF10811.8 PVD35555.1 - 0.031 14.3 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Myc_N PF01056.18 PVD35555.1 - 0.045 13.7 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DHC_N1 PF08385.12 PVD35555.1 - 0.097 11.3 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Ank PF00023.30 PVD35555.1 - 0.26 11.8 1.1 9.3 6.9 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat Shisa PF13908.6 PVD35556.1 - 1 9.5 10.2 0.079 13.2 4.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Alk_phosphatase PF00245.20 PVD35557.1 - 6.4e-174 578.8 7.4 1.2e-138 462.6 1.9 2.3 2 1 0 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 PVD35557.1 - 9.1e-05 21.9 0.6 0.00034 20.1 0.5 2.0 2 1 0 2 2 2 1 Metalloenzyme superfamily Phosphodiest PF01663.22 PVD35557.1 - 0.012 15.2 0.3 0.02 14.5 0.3 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 PVD35558.1 - 3.9e-61 207.3 0.1 9e-61 206.0 0.1 1.5 1 1 0 1 1 1 1 Alkaline phosphatase CHGN PF05679.16 PVD35559.1 - 1.2e-65 222.3 0.0 2e-45 155.6 0.0 3.1 3 0 0 3 3 3 3 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 PVD35559.1 - 5.8e-12 45.6 0.0 5.2e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 PVD35559.1 - 3.5e-08 33.0 0.0 1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 PVD35559.1 - 0.011 15.2 0.0 0.049 13.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 NHL PF01436.21 PVD35561.1 - 4.9e-22 76.8 2.7 2.2e-06 27.4 0.3 6.9 6 1 0 6 6 6 4 NHL repeat Filamin PF00630.19 PVD35561.1 - 6.8e-13 49.3 0.0 2.1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 PVD35561.1 - 4.6e-06 26.7 4.5 8.3e-06 25.9 4.5 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF5128 PF17170.4 PVD35561.1 - 3.4e-05 23.1 1.5 0.0072 15.5 1.1 3.2 2 1 1 3 3 3 1 6-bladed beta-propeller SdiA-regulated PF06977.11 PVD35561.1 - 0.00036 19.8 0.4 0.0016 17.7 0.0 2.2 2 1 1 3 3 3 1 SdiA-regulated SGL PF08450.12 PVD35561.1 - 0.0015 18.2 0.1 0.17 11.5 0.0 2.8 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Invasin_D3 PF09134.10 PVD35561.1 - 0.0023 18.2 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Invasin, domain 3 K-box PF01486.17 PVD35561.1 - 0.0098 16.0 1.7 0.18 12.0 0.9 2.5 2 0 0 2 2 2 1 K-box region TolA_bind_tri PF16331.5 PVD35561.1 - 0.085 12.9 1.0 0.2 11.7 1.0 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.12 PVD35561.1 - 0.1 12.7 4.2 0.27 11.3 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PVD35561.1 - 0.11 12.9 1.9 0.97 9.9 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 PVD35561.1 - 0.19 12.0 2.0 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RNA_pol_Rpb5_C PF01191.19 PVD35561.1 - 0.21 11.4 0.6 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Tmemb_9 PF05434.11 PVD35561.1 - 0.37 10.7 4.3 0.69 9.8 4.2 1.5 1 1 0 1 1 1 0 TMEM9 ING PF12998.7 PVD35561.1 - 1.7 9.3 5.5 4 8.1 4.7 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M90 PF06167.12 PVD35562.1 - 7.5e-06 25.7 4.6 0.088 12.4 0.3 3.2 2 1 1 3 3 3 2 Glucose-regulated metallo-peptidase M90 Peptidase_M90 PF06167.12 PVD35563.1 - 6.3e-06 26.0 20.5 0.13 11.8 0.3 6.5 4 3 1 5 5 5 3 Glucose-regulated metallo-peptidase M90 SprT-like PF10263.9 PVD35563.1 - 0.00074 19.4 0.0 11 6.0 0.0 3.4 3 0 0 3 3 3 2 SprT-like family Peptidase_M10 PF00413.24 PVD35563.1 - 0.0017 18.2 0.5 0.38 10.6 0.2 2.9 2 1 0 2 2 2 1 Matrixin DUF4712 PF15830.5 PVD35563.1 - 0.035 13.8 0.0 4.8 6.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4712) SMRP1 PF15181.6 PVD35563.1 - 0.056 13.0 0.6 9.4 5.7 0.0 3.2 3 0 0 3 3 3 0 Spermatid-specific manchette-related protein 1 DUF4932 PF16286.5 PVD35563.1 - 0.13 11.5 1.5 37 3.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4932) Peptidase_M91 PF14891.6 PVD35563.1 - 0.15 12.4 0.7 6.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Effector protein Glyco_hydro_7 PF00840.20 PVD35563.1 - 0.32 9.7 8.5 2.6 6.6 0.3 3.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 7 SAP PF02037.27 PVD35564.1 - 9.3e-09 34.9 0.9 3.6e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 SAP domain Peptidase_M23 PF01551.22 PVD35564.1 - 7.3e-06 26.1 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M23 Ish1 PF10281.9 PVD35564.1 - 0.00095 19.4 0.1 0.0031 17.8 0.1 1.9 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein fn3 PF00041.21 PVD35565.1 - 1.4e-05 25.3 16.5 4.6 7.6 0.0 8.9 9 1 0 9 9 9 3 Fibronectin type III domain PAN_1 PF00024.26 PVD35565.1 - 2.7e-05 24.0 0.1 7.8e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 PAN domain CYYR1 PF10873.8 PVD35565.1 - 0.00052 20.5 1.7 0.0017 18.8 1.7 1.8 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 EGF PF00008.27 PVD35565.1 - 0.039 14.2 24.0 0.77 10.1 2.4 3.9 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 PVD35565.1 - 0.083 13.6 19.9 1.6 9.5 2.1 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF DUF2567 PF10821.8 PVD35565.1 - 0.13 12.4 1.2 0.25 11.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Cadherin_4 PF17803.1 PVD35565.1 - 0.19 12.4 4.0 2 9.1 0.5 3.9 2 0 0 2 2 2 0 Bacterial cadherin-like domain RT_RNaseH_2 PF17919.1 PVD35568.1 - 4.1e-33 113.4 0.0 6.1e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PVD35568.1 - 4.3e-26 91.8 0.0 7.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 PVD35568.1 - 2.5e-24 85.6 0.0 4.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Big_9 PF17963.1 PVD35569.1 - 0.0013 19.4 12.7 0.064 14.0 0.0 3.7 3 0 0 3 3 3 2 Bacterial Ig domain DUF782 PF05614.11 PVD35569.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) Cadherin_3 PF16184.5 PVD35569.1 - 0.16 12.0 1.5 2.1 8.4 0.1 2.7 3 0 0 3 3 3 0 Cadherin-like Cadherin_4 PF17803.1 PVD35569.1 - 5.4 7.7 15.1 0.19 12.4 1.0 3.6 4 0 0 4 4 4 0 Bacterial cadherin-like domain AAA PF00004.29 PVD35570.1 - 8.6e-41 139.5 0.0 1.9e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD35570.1 - 1.9e-08 34.0 0.1 3.9e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PVD35570.1 - 0.00013 22.2 0.0 0.004 17.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PVD35570.1 - 0.00016 21.7 0.1 0.00073 19.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PVD35570.1 - 0.00069 18.9 0.0 0.0032 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 PVD35570.1 - 0.00091 19.4 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PVD35570.1 - 0.0018 18.7 0.1 0.03 14.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PVD35570.1 - 0.0057 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PVD35570.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PVD35570.1 - 0.015 14.8 0.0 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 PVD35570.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PVD35570.1 - 0.02 15.4 0.0 0.055 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 PVD35570.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PVD35570.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PVD35570.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 PVD35570.1 - 0.093 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 PVD35570.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 PVD35570.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PVD35570.1 - 0.15 11.8 0.1 0.81 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PVD35570.1 - 0.17 11.5 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Arf PF00025.21 PVD35571.1 - 2.5e-52 176.9 0.0 3.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PVD35571.1 - 1.8e-08 34.7 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD35571.1 - 2.6e-07 30.4 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PVD35571.1 - 1.7e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD35571.1 - 0.0078 15.4 0.1 0.018 14.2 0.1 1.6 1 1 1 2 2 2 1 G-protein alpha subunit PI3_PI4_kinase PF00454.27 PVD35572.1 - 9.6e-76 254.9 0.2 1.5e-75 254.2 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 PVD35572.1 - 9.1e-45 151.1 0.4 9.1e-45 151.1 0.4 2.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FAT PF02259.23 PVD35572.1 - 1.5e-37 129.7 0.5 2.5e-37 128.9 0.5 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 PVD35572.1 - 5.1e-10 39.0 1.6 8.3e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 FATC domain Aida_N PF08910.10 PVD35572.1 - 0.06 13.7 1.0 6.9 7.1 0.1 3.0 2 0 0 2 2 2 0 Aida N-terminus DUF3385 PF11865.8 PVD35573.1 - 2.1e-53 180.6 10.7 3.3e-50 170.2 0.1 6.2 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 PVD35573.1 - 4.8e-40 137.8 1.7 4.8e-40 137.8 1.7 3.1 2 1 0 2 2 2 1 FAT domain HEAT_2 PF13646.6 PVD35573.1 - 5.3e-14 52.4 0.9 0.031 14.6 0.0 9.1 8 2 2 10 10 10 3 HEAT repeats HEAT_EZ PF13513.6 PVD35573.1 - 3e-12 46.7 19.5 0.003 18.0 0.1 9.3 10 2 1 12 12 9 4 HEAT-like repeat HEAT PF02985.22 PVD35573.1 - 2e-11 43.1 11.9 0.0015 18.6 0.0 11.7 12 0 0 12 12 11 1 HEAT repeat Adaptin_N PF01602.20 PVD35573.1 - 4.5e-06 25.5 7.5 0.00048 18.8 3.5 4.8 3 3 0 3 3 3 1 Adaptin N terminal region Sec7_N PF12783.7 PVD35573.1 - 1e-05 25.5 1.3 0.22 11.4 0.0 5.0 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 PVD35573.1 - 0.00012 22.6 4.8 0.75 10.4 0.0 6.8 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region TPR_19 PF14559.6 PVD35573.1 - 0.0015 19.0 3.1 0.0065 16.9 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Cnd1 PF12717.7 PVD35573.1 - 0.0059 16.7 6.3 0.028 14.5 0.1 4.9 6 2 2 8 8 7 1 non-SMC mitotic condensation complex subunit 1 TPR_9 PF13371.6 PVD35573.1 - 0.068 13.3 0.3 0.61 10.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe_hyd_lg_C PF02906.14 PVD35573.1 - 0.091 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CLASP_N PF12348.8 PVD35573.1 - 1.8 8.1 13.6 2.7 7.5 0.0 5.3 8 1 0 8 8 8 0 CLASP N terminal UME PF08064.13 PVD35573.1 - 3.7 7.5 11.3 1.7 8.6 0.0 5.6 6 1 1 7 7 7 0 UME (NUC010) domain TPR_2 PF07719.17 PVD35573.1 - 6 7.2 12.5 3 8.2 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UbiA PF01040.18 PVD35574.1 - 2.1e-37 128.8 10.9 2.7e-37 128.5 10.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NADH-u_ox-rdase PF10785.9 PVD35574.1 - 0.17 12.6 1.5 41 4.9 0.0 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit GARS_A PF01071.19 PVD35576.1 - 2.6e-76 255.7 0.0 4.2e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 PVD35576.1 - 2.3e-63 213.2 0.8 5.5e-62 208.7 0.1 2.3 2 0 0 2 2 2 1 Formyl transferase GARS_N PF02844.15 PVD35576.1 - 1.4e-34 118.8 0.9 1.1e-33 115.9 0.0 2.8 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 PVD35576.1 - 4.3e-34 117.9 0.0 1.2e-33 116.5 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 PVD35576.1 - 6.5e-28 96.8 0.2 2.6e-27 94.9 0.2 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 PVD35576.1 - 9.9e-16 58.2 1.7 9.9e-16 58.2 1.7 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_2 PF08442.10 PVD35576.1 - 7.9e-05 22.3 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 PVD35576.1 - 0.0094 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PVD35576.1 - 0.13 11.8 1.5 0.28 10.6 0.2 2.3 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 PVD35576.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DM13 PF10517.9 PVD35576.1 - 0.17 12.5 0.0 0.56 10.8 0.0 1.8 1 0 0 1 1 1 0 Electron transfer DM13 Mito_carr PF00153.27 PVD35577.1 - 1.8e-67 223.3 7.4 1.2e-23 82.9 1.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Clc-like PF07062.12 PVD35577.1 - 0.14 11.6 1.6 13 5.2 0.1 2.5 2 1 0 2 2 2 0 Clc-like Filament PF00038.21 PVD35578.1 - 0.00024 20.8 12.8 0.00024 20.8 12.8 3.2 1 1 2 3 3 3 3 Intermediate filament protein DUF1033 PF06279.11 PVD35578.1 - 0.089 13.0 2.8 1.4 9.1 0.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) zf-C2H2 PF00096.26 PVD35579.1 - 7.9e-20 70.1 43.7 3.7e-05 23.9 3.3 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD35579.1 - 2e-14 53.3 35.3 2.9e-05 24.3 0.6 6.2 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD35579.1 - 4.9e-10 39.4 44.5 0.038 14.8 2.2 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD35579.1 - 0.0015 18.8 23.9 0.12 12.7 0.5 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 PVD35579.1 - 0.0044 16.9 10.1 0.13 12.1 0.5 3.0 3 0 0 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 PVD35579.1 - 0.012 16.3 18.9 0.18 12.5 5.7 3.7 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 PVD35579.1 - 0.014 15.7 18.5 0.041 14.2 6.4 3.9 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PVD35579.1 - 0.054 13.5 42.5 0.11 12.5 1.2 5.8 6 0 0 6 6 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PVD35579.1 - 0.089 13.1 34.6 0.48 10.8 2.1 5.4 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 PVD35579.1 - 0.13 12.4 8.8 15 5.8 0.1 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 PVD35579.1 - 0.41 11.1 30.0 0.24 11.8 1.5 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 PVD35579.1 - 0.47 10.4 9.0 9.9 6.2 0.2 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type BIR PF00653.21 PVD35579.1 - 0.68 10.6 9.2 68 4.2 5.8 3.1 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain zf-MYST PF17772.1 PVD35579.1 - 1.3 8.6 0.0 1.3 8.6 0.0 3.7 4 0 0 4 4 4 0 MYST family zinc finger domain DUF371 PF04027.13 PVD35583.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) zf-H2C2_2 PF13465.6 PVD35586.1 - 3.8e-33 112.4 69.1 1.3e-07 31.7 1.9 9.5 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 PVD35586.1 - 3.3e-32 109.1 74.7 1.3e-05 25.3 3.5 9.3 9 1 1 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD35586.1 - 9.9e-21 72.7 70.3 0.0033 18.1 0.7 9.2 9 1 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 PVD35586.1 - 0.0011 19.3 56.4 0.031 14.7 0.6 8.3 8 0 0 8 8 8 6 Zinc-finger of C2H2 type DUF3991 PF13154.6 PVD35586.1 - 0.01 16.2 0.6 6.3 7.2 0.0 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3991) zf-C2H2_6 PF13912.6 PVD35586.1 - 0.37 10.9 51.2 0.038 14.0 3.5 7.8 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.12 PVD35586.1 - 0.6 10.4 46.0 0.071 13.4 8.6 5.0 1 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding AA_permease PF00324.21 PVD35588.1 - 3.6e-77 260.0 41.9 4.6e-61 206.9 22.3 2.1 1 1 1 2 2 2 2 Amino acid permease SLC12 PF03522.15 PVD35588.1 - 7.8e-11 41.6 0.0 7.8e-11 41.6 0.0 9.9 2 1 3 5 5 5 2 Solute carrier family 12 EphA2_TM PF14575.6 PVD35590.1 - 0.015 16.2 0.1 0.039 14.8 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Death PF00531.22 PVD35590.1 - 0.03 14.5 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 Death domain Protocadherin PF08374.11 PVD35590.1 - 0.036 14.0 0.3 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 Protocadherin RNA_pol_Rpb2_2 PF04561.14 PVD35590.1 - 0.041 13.5 0.1 0.062 12.9 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Syndecan PF01034.20 PVD35590.1 - 0.041 13.8 3.4 0.13 12.2 3.4 1.8 1 0 0 1 1 1 0 Syndecan domain NICE-3 PF07406.11 PVD35590.1 - 0.049 13.6 0.5 0.078 13.0 0.5 1.3 1 0 0 1 1 1 0 NICE-3 protein Glycophorin_A PF01102.18 PVD35590.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A DnaA_N PF11638.8 PVD35591.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 DnaA N-terminal domain 7tm_1 PF00001.21 PVD35592.1 - 5e-07 29.3 2.7 6.8e-07 28.9 2.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 PVD35592.1 - 0.078 13.3 0.0 0.094 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.21 PVD35593.1 - 9.4e-07 28.4 1.3 4e-06 26.4 1.2 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD35593.1 - 0.012 15.0 0.5 0.019 14.2 0.5 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw SOCS PF12610.8 PVD35593.1 - 0.046 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Suppressor of cytokine signalling 7TM_GPCR_Srx PF10328.9 PVD35593.1 - 3.7 7.1 9.0 0.38 10.3 4.6 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx ABC_tran PF00005.27 PVD35594.1 - 1.4e-31 109.9 1.2 1.9e-21 77.0 0.0 3.3 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 PVD35594.1 - 8.4e-23 80.2 5.7 8.4e-23 80.2 5.7 2.7 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 PVD35594.1 - 1.3e-13 51.4 3.9 0.00025 21.0 0.0 3.6 2 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD35594.1 - 7.8e-10 38.6 0.0 6.7e-07 29.0 0.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 PVD35594.1 - 0.012 15.8 1.0 3.7 7.9 0.3 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF1672 PF07901.11 PVD35594.1 - 0.012 14.9 2.0 0.012 14.9 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) GBP_repeat PF02526.14 PVD35594.1 - 0.13 12.0 2.1 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Glycophorin-binding protein AAA_18 PF13238.6 PVD35594.1 - 0.23 12.0 2.4 2.3 8.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain Ski_Sno PF02437.17 PVD35598.1 - 8.7e-42 141.2 5.4 1.3e-41 140.7 2.7 2.4 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 PVD35598.1 - 1e-33 115.4 5.0 2.2e-33 114.3 5.0 1.6 1 0 0 1 1 1 1 c-SKI Smad4 binding domain FUSC PF04632.12 PVD35598.1 - 2.6 6.4 9.5 4.5 5.7 9.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 PVD35598.1 - 2.8 8.6 11.6 6.7 7.4 0.8 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Spc24 PF08286.11 PVD35598.1 - 3.5 7.9 8.8 1.4e+02 2.7 8.8 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GAS PF13851.6 PVD35598.1 - 3.9 6.8 26.6 0.15 11.4 1.4 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding XG_FTase PF03254.13 PVD35600.1 - 0.028 13.0 0.0 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase XG_FTase PF03254.13 PVD35601.1 - 0.047 12.3 0.1 0.59 8.7 0.0 2.1 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Glyco_transf_8 PF01501.20 PVD35602.1 - 1.7e-51 175.3 0.1 2e-51 175.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 PVD35602.1 - 4e-07 29.7 0.2 7.4e-07 28.8 0.2 1.4 1 1 0 1 1 1 1 Glucosyltransferase 24 Methyltr_RsmB-F PF01189.17 PVD35603.1 - 1.4e-27 96.6 0.1 2.3e-27 96.0 0.1 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PVD35603.1 - 0.00024 21.3 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PVD35603.1 - 0.0031 17.3 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD35603.1 - 0.016 15.9 0.0 0.049 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HPS3_N PF14761.6 PVD35604.1 - 0.095 12.2 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Ank_2 PF12796.7 PVD35606.1 - 3.5e-58 194.2 11.1 3.9e-14 53.0 0.1 4.8 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35606.1 - 1.4e-40 137.1 3.1 2e-10 41.0 0.0 5.8 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35606.1 - 1.4e-36 124.0 8.2 9.9e-07 28.9 0.1 7.5 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35606.1 - 1.9e-24 83.0 4.1 0.026 15.0 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 PVD35606.1 - 4.3e-17 61.7 12.5 0.12 12.9 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Phostensin_N PF13916.6 PVD35606.1 - 0.016 15.5 0.3 0.16 12.3 0.1 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF1843 PF08898.10 PVD35606.1 - 0.043 14.3 0.1 0.043 14.3 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Galactosyl_T PF01762.21 PVD35607.1 - 1.6e-35 122.7 0.0 2.5e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Synaptobrevin PF00957.21 PVD35608.1 - 1.4e-35 120.9 4.0 1.7e-35 120.7 4.0 1.0 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.9 PVD35608.1 - 0.0012 18.6 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Corona_S2 PF01601.16 PVD35608.1 - 0.016 13.7 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein 7tm_3 PF00003.22 PVD35608.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Virul_fac_BrkB PF03631.15 PVD35608.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF4307 PF14155.6 PVD35608.1 - 0.075 12.9 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) MCU PF04678.13 PVD35608.1 - 0.077 13.1 0.1 0.092 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF898 PF05987.13 PVD35608.1 - 0.079 12.0 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 PVD35608.1 - 0.083 11.6 0.0 0.088 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LMBR1 PF04791.16 PVD35608.1 - 0.086 11.7 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Orf78 PF06024.12 PVD35608.1 - 0.1 12.9 0.5 0.15 12.4 0.4 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF4736 PF15883.5 PVD35608.1 - 0.11 12.2 5.1 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) ATG16 PF08614.11 PVD35608.1 - 0.12 12.6 2.8 0.16 12.2 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 PVD35608.1 - 0.13 11.5 9.7 0.25 10.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ASFV_J13L PF05568.11 PVD35608.1 - 0.4 10.4 7.2 0.31 10.8 5.3 1.7 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF4519 PF15012.6 PVD35608.1 - 1.2 9.4 3.5 0.53 10.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Collectrin PF16959.5 PVD35608.1 - 2.3 8.0 8.2 3 7.6 8.2 1.3 1 1 0 1 1 1 0 Renal amino acid transporter Period_C PF12114.8 PVD35609.1 - 9.7e-10 38.4 32.4 3e-08 33.5 4.6 5.6 5 1 0 5 5 5 2 Period protein 2/3C-terminal region HLH PF00010.26 PVD35609.1 - 0.0032 17.4 0.0 0.014 15.4 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1664 PF07889.12 PVD35609.1 - 0.87 9.6 0.0 0.87 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) zf-RING_9 PF13901.6 PVD35610.1 - 3.6e-53 180.6 8.7 8.6e-53 179.4 8.7 1.6 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 PVD35610.1 - 3.7e-21 75.5 1.6 4.8e-21 75.1 0.1 2.1 2 0 0 2 2 2 1 RUN domain BORG_CEP PF14957.6 PVD35610.1 - 5.4 8.2 15.8 1.1 10.5 0.4 2.6 1 1 1 2 2 2 0 Cdc42 effector Glyco_hydro_79n PF03662.14 PVD35611.1 - 1.6e-38 132.4 0.1 3e-17 62.5 0.0 3.2 2 1 1 3 3 3 3 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.14 PVD35612.1 - 2.5e-20 72.7 0.0 2.5e-14 52.9 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.14 PVD35613.1 - 5.4e-10 38.7 0.0 6.7e-07 28.5 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain TRAP-gamma PF07074.12 PVD35614.1 - 3.2e-77 257.9 5.7 3.7e-77 257.7 5.7 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Peptidase_M3_N PF08439.10 PVD35614.1 - 0.021 15.1 0.7 4.6 7.6 0.2 2.2 2 0 0 2 2 2 0 Oligopeptidase F DUF4579 PF15158.6 PVD35614.1 - 0.093 12.5 2.0 0.12 12.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) PDEase_I PF00233.19 PVD35616.1 - 7.6e-86 287.7 0.1 1.5e-85 286.8 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ank_4 PF13637.6 PVD35617.1 - 3.1e-34 116.9 10.5 6.8e-09 36.1 0.2 7.6 6 2 3 9 9 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35617.1 - 5.6e-34 116.6 28.2 1.9e-12 47.6 2.0 5.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD35617.1 - 1.6e-29 101.5 14.2 7.7e-06 26.1 1.4 8.1 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 PVD35617.1 - 6.4e-27 92.8 20.7 3.2e-06 27.3 0.2 9.0 7 2 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 PVD35617.1 - 3.7e-24 82.2 15.8 7.9e-06 25.8 0.0 9.2 8 1 1 9 9 9 5 Ankyrin repeat SH3_15 PF18346.1 PVD35617.1 - 4.1e-20 71.8 1.5 1.3e-18 67.1 0.1 3.1 2 0 0 2 2 2 1 Mind bomb SH3 repeat domain MIB_HERC2 PF06701.13 PVD35617.1 - 1.7e-19 69.8 10.9 9.1e-10 38.7 0.2 3.2 2 1 1 3 3 3 2 Mib_herc2 zf-C3HC4_3 PF13920.6 PVD35617.1 - 3.2e-05 23.7 12.3 6.3e-05 22.7 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD35617.1 - 0.012 15.4 12.4 0.029 14.2 12.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Tudor_3 PF18115.1 PVD35617.1 - 0.19 11.6 0.2 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF4314 PF14192.6 PVD35617.1 - 1.4 8.8 5.7 4.2 7.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) zf-C3HC4_2 PF13923.6 PVD35617.1 - 2.5 8.0 15.0 5.7 6.9 15.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 PVD35618.1 - 2.5e-40 136.9 8.9 1.1e-10 42.0 0.1 5.4 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD35618.1 - 1.3e-37 127.4 1.7 3.6e-09 36.7 0.0 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD35618.1 - 1.8e-37 126.2 4.7 2.7e-05 24.4 0.1 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 PVD35618.1 - 1.1e-36 124.7 4.6 2.3e-10 40.8 0.0 7.2 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35618.1 - 9.6e-32 105.5 1.2 0.0004 20.6 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat MIB_HERC2 PF06701.13 PVD35618.1 - 5.1e-24 84.3 12.5 1.7e-12 47.4 8.2 3.1 3 0 0 3 3 3 2 Mib_herc2 SH3_15 PF18346.1 PVD35618.1 - 1.3e-15 57.4 4.4 8.2e-07 29.2 0.0 3.4 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 PVD35619.1 - 8.7e-47 157.6 6.7 9.5e-17 61.4 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35619.1 - 8.6e-36 121.9 2.4 4.1e-10 40.0 0.1 6.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD35619.1 - 9.6e-32 108.0 9.8 5.8e-06 26.5 0.1 8.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 PVD35619.1 - 3.4e-29 100.5 2.4 3.7e-08 33.5 0.1 5.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35619.1 - 6.2e-23 78.4 1.8 0.0007 19.9 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat SH3_15 PF18346.1 PVD35619.1 - 1.6e-18 66.8 0.3 5.2e-18 65.1 0.3 2.0 1 0 0 1 1 1 1 Mind bomb SH3 repeat domain LSDAT_euk PF18139.1 PVD35619.1 - 9.9e-08 31.7 0.0 3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 SLOG in TRPM DUF4448 PF14610.6 PVD35619.1 - 0.015 15.1 0.3 0.015 15.1 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Ion_trans PF00520.31 PVD35619.1 - 0.024 13.8 31.4 0.0078 15.5 27.3 2.1 1 1 1 2 2 2 0 Ion transport protein GLTP PF08718.11 PVD35619.1 - 3.8 7.8 8.1 21 5.3 0.3 2.8 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Mfa2 PF08842.10 PVD35620.1 - 0.031 13.9 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 QVR PF17064.5 PVD35622.1 - 7.1e-24 83.9 5.3 9.8e-24 83.4 5.3 1.2 1 0 0 1 1 1 1 Sleepless protein Activin_recp PF01064.23 PVD35622.1 - 0.015 16.3 4.5 0.015 16.3 4.5 1.7 2 1 0 2 2 2 0 Activin types I and II receptor domain Methyltransf_FA PF12248.8 PVD35623.1 - 7.9e-11 42.2 0.0 1.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase SprA-related PF12118.8 PVD35623.1 - 0.22 10.7 6.1 0.29 10.2 6.1 1.1 1 0 0 1 1 1 0 SprA-related family PHD PF00628.29 PVD35624.1 - 1.6e-27 95.2 56.7 3.5e-09 36.4 8.9 5.6 6 0 0 6 6 6 4 PHD-finger zf-HC5HC2H_2 PF13832.6 PVD35624.1 - 1.3e-26 92.9 27.8 1.8e-24 86.0 3.9 4.5 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PVD35624.1 - 3.5e-20 72.0 32.5 6.7e-17 61.5 2.6 4.9 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.6 PVD35624.1 - 6.3e-06 25.6 7.9 6.3e-06 25.6 7.9 6.2 5 2 0 5 5 4 2 PHD-finger Prok-RING_1 PF14446.6 PVD35624.1 - 0.0021 17.9 4.0 0.0021 17.9 4.0 5.1 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 DUF2353 PF09789.9 PVD35624.1 - 0.005 16.2 2.8 0.005 16.2 2.8 2.1 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DUF4795 PF16043.5 PVD35624.1 - 0.0057 16.3 1.1 0.0057 16.3 1.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4795) Spc7 PF08317.11 PVD35624.1 - 0.011 14.6 3.3 0.027 13.4 3.3 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 PVD35624.1 - 0.015 15.4 5.7 0.043 13.9 5.7 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 PVD35624.1 - 0.046 13.6 6.8 0.015 15.2 3.4 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 PVD35624.1 - 0.1 12.7 5.4 0.26 11.4 5.4 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation TSC22 PF01166.18 PVD35624.1 - 0.36 11.2 3.7 0.42 11.0 1.7 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DegS PF05384.11 PVD35624.1 - 0.52 9.8 11.8 0.013 15.0 4.1 2.1 2 0 0 2 2 2 0 Sensor protein DegS YabA PF06156.13 PVD35624.1 - 0.98 10.1 6.0 0.38 11.4 2.0 2.4 2 0 0 2 2 1 0 Initiation control protein YabA DivIC PF04977.15 PVD35624.1 - 1.6 8.5 8.1 4.4 7.2 6.6 2.4 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 PVD35624.1 - 2.2 8.8 15.8 0.03 14.9 5.9 2.9 3 0 0 3 3 2 0 Apg6 coiled-coil region FANCL_C PF11793.8 PVD35624.1 - 2.2 8.5 34.7 0.33 11.1 2.3 4.6 4 0 0 4 4 4 0 FANCL C-terminal domain ZapB PF06005.12 PVD35624.1 - 5.6 7.5 15.6 0.092 13.2 7.5 2.3 2 0 0 2 2 1 0 Cell division protein ZapB DASH_Spc34 PF08657.10 PVD35624.1 - 6.4 6.5 15.2 0.015 15.1 3.5 2.3 3 0 0 3 3 2 0 DASH complex subunit Spc34 zf-UBP_var PF17807.1 PVD35624.1 - 9.4 6.1 10.5 3.1 7.6 3.9 3.2 3 0 0 3 3 3 0 Variant UBP zinc finger RasGAP_C PF03836.15 PVD35624.1 - 9.7 6.3 12.1 0.067 13.3 0.9 2.6 3 0 0 3 3 2 0 RasGAP C-terminus zf-H2C2_2 PF13465.6 PVD35625.1 - 2.7e-46 154.0 96.9 1.1e-07 31.9 0.8 16.7 19 0 0 19 19 19 11 Zinc-finger double domain zf-C2H2 PF00096.26 PVD35625.1 - 9.3e-45 148.7 114.2 6.3e-07 29.5 0.5 15.6 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD35625.1 - 1.1e-32 109.9 109.6 0.0012 19.5 0.2 15.6 14 1 1 15 15 15 13 C2H2-type zinc finger zf-met PF12874.7 PVD35625.1 - 5.1e-10 39.4 79.1 0.0017 18.6 1.1 13.2 15 0 0 15 15 15 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD35625.1 - 9.4e-10 38.5 53.2 0.0012 19.1 0.5 12.6 12 0 0 12 12 12 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PVD35625.1 - 0.01 15.6 0.2 0.01 15.6 0.2 11.8 12 1 0 12 12 12 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 PVD35625.1 - 0.019 15.3 1.1 0.019 15.3 1.1 10.2 9 2 2 11 11 11 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 PVD35625.1 - 1 9.2 26.8 0.41 10.5 0.1 6.6 4 2 3 7 7 7 0 GAGA factor DUF3268 PF11672.8 PVD35625.1 - 3.4 8.0 18.6 3.9 7.8 0.3 5.7 5 1 1 6 6 6 0 zinc-finger-containing domain zf_ZIC PF18366.1 PVD35625.1 - 5.7 7.1 14.3 36 4.6 0.0 5.6 5 0 0 5 5 5 0 Zic proteins zinc finger domain ECH_2 PF16113.5 PVD35626.1 - 5.5e-140 466.6 0.0 7e-140 466.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PVD35626.1 - 1.2e-28 100.1 0.4 1.4e-27 96.7 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Mito_fiss_reg PF05308.11 PVD35627.1 - 3 7.9 10.1 2.4 8.2 8.6 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator Homeodomain PF00046.29 PVD35628.1 - 6.7e-21 73.9 4.2 1e-20 73.3 4.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD35628.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 PVD35628.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pex14_N PF04695.13 PVD35628.1 - 4.8 7.8 17.9 25 5.5 17.9 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dpy-30 PF05186.13 PVD35630.1 - 9.3e-10 38.0 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif CadC_C1 PF18500.1 PVD35631.1 - 0.065 13.4 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 CadC C-terminal domain 1 adh_short_C2 PF13561.6 PVD35632.1 - 2e-51 174.8 0.1 2.5e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD35632.1 - 1.1e-44 152.2 0.1 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD35632.1 - 8.9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 PVD35632.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 PVD35632.1 - 0.0016 17.7 0.2 0.0037 16.5 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PVD35632.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 PVD35632.1 - 0.051 14.2 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 PVD35632.1 - 0.062 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase E1-E2_ATPase PF00122.20 PVD35633.1 - 9e-41 139.4 2.3 4e-40 137.3 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PVD35633.1 - 3.6e-24 84.7 0.0 2e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PVD35633.1 - 1.1e-16 60.3 0.0 2.2e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PVD35633.1 - 0.0084 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MgtE PF01769.16 PVD35633.1 - 0.01 16.2 6.2 0.35 11.3 3.1 2.3 2 0 0 2 2 2 0 Divalent cation transporter DUF3290 PF11694.8 PVD35633.1 - 0.17 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2207 PF09972.9 PVD35633.1 - 2.2 6.9 7.4 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cation_ATPase_C PF00689.21 PVD35634.1 - 5.6e-44 150.0 1.1 7.5e-44 149.6 1.1 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PVD35634.1 - 6.4e-17 62.5 0.0 2.1e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PVD35634.1 - 4e-07 30.1 0.8 0.0005 19.9 0.7 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PVD35634.1 - 0.0014 19.0 0.0 0.017 15.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NAD_Gly3P_dh_N PF01210.23 PVD35635.1 - 1.1e-50 171.7 2.3 1.7e-50 171.1 1.9 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PVD35635.1 - 4.1e-46 156.8 1.6 4.6e-46 156.6 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 PVD35635.1 - 0.0071 16.9 1.0 0.068 13.8 1.0 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 PVD35635.1 - 0.0075 15.8 0.9 0.59 9.7 0.0 2.6 3 0 0 3 3 3 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain PAS_9 PF13426.7 PVD35635.1 - 0.072 13.3 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain Glyco_hydro_18 PF00704.28 PVD35636.1 - 5.2e-36 125.0 0.0 6.5e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Imm6 PF14434.6 PVD35636.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 Glyco_hydro_18 PF00704.28 PVD35637.1 - 1.7e-34 120.0 0.1 2.7e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD35638.1 - 0.029 14.5 6.6 0.03 14.5 2.3 2.3 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Metallothio_Pro PF02069.16 PVD35639.1 - 1.4 9.2 10.2 1.1 9.5 1.4 3.3 3 0 0 3 3 3 0 Prokaryotic metallothionein Acyl-ACP_TE PF01643.17 PVD35641.1 - 4.9e-05 22.7 0.0 7.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 PVD35641.1 - 0.022 15.2 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 PVD35642.1 - 0.063 12.6 0.0 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 Acyl-ACP thioesterase adh_short_C2 PF13561.6 PVD35643.1 - 2.4e-46 158.2 0.1 4e-46 157.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD35643.1 - 7.9e-37 126.6 0.2 1.6e-36 125.6 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ank_2 PF12796.7 PVD35643.1 - 5.2e-28 97.4 3.9 6.5e-08 33.1 0.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35643.1 - 3.3e-23 81.7 4.3 0.00083 19.9 0.1 6.5 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35643.1 - 3.5e-16 57.6 7.1 0.1 13.2 0.1 8.0 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD35643.1 - 1.7e-15 56.9 4.0 0.00016 21.9 0.2 5.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD35643.1 - 3.6e-15 55.6 9.2 0.0043 17.5 0.5 6.8 5 1 0 5 5 5 4 Ankyrin repeat 3HCDH_N PF02737.18 PVD35643.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tubulin-binding PF00418.19 PVD35644.1 - 2.7e-44 148.8 30.8 5.7e-15 55.0 0.4 5.4 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat TFIIA PF03153.13 PVD35644.1 - 7.9 6.4 26.3 10 6.0 26.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tubulin-binding PF00418.19 PVD35645.1 - 9.9e-29 99.1 7.2 5.8e-10 39.0 0.0 5.1 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat UreE_N PF02814.15 PVD35651.1 - 5.3 6.7 7.2 44 3.8 0.9 3.1 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain PocR PF10114.9 PVD35659.1 - 0.038 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR Homeodomain PF00046.29 PVD35660.1 - 2.9e-20 71.9 9.5 4.8e-20 71.2 9.5 1.4 1 0 0 1 1 1 1 Homeodomain TAF4 PF05236.14 PVD35660.1 - 0.042 13.6 5.8 0.054 13.2 5.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family LCD1 PF09798.9 PVD35663.1 - 0.22 10.0 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Homeodomain PF00046.29 PVD35666.1 - 1.1e-20 73.2 6.9 1.9e-20 72.4 6.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD35666.1 - 0.14 12.1 0.4 0.39 10.7 0.4 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 PVD35668.1 - 2.5e-21 75.2 8.5 4.1e-21 74.6 8.5 1.3 1 0 0 1 1 1 1 Homeodomain Loricrin PF15847.5 PVD35669.1 - 7.6 5.5 39.2 0.29 10.2 28.7 2.6 3 0 0 3 3 3 0 Major keratinocyte cell envelope protein Homeodomain PF00046.29 PVD35670.1 - 6.7e-09 35.5 2.1 8.7e-09 35.1 2.1 1.1 1 0 0 1 1 1 1 Homeodomain DUF4768 PF15989.5 PVD35670.1 - 0.05 13.6 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) Sulfotransfer_3 PF13469.6 PVD35671.1 - 5.6e-33 115.1 0.0 7.5e-15 55.9 0.0 2.9 2 2 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD35671.1 - 3.9e-32 111.8 0.3 2.1e-14 53.7 0.2 3.5 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_4 PF17784.1 PVD35671.1 - 0.068 13.0 0.1 20 4.9 0.0 2.9 2 1 1 3 3 3 0 Sulfotransferase domain zf-C2H2_2 PF12756.7 PVD35671.1 - 0.11 12.8 0.0 20 5.6 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Sulfotransfer_1 PF00685.27 PVD35672.1 - 1.4e-05 24.7 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD35672.1 - 0.001 19.5 0.0 0.0029 18.0 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family ATP-synt_C PF00137.21 PVD35674.1 - 2.9e-10 40.3 11.9 2.9e-10 40.3 11.9 1.5 2 0 0 2 2 2 1 ATP synthase subunit C Phage_holin_3_6 PF07332.11 PVD35674.1 - 6.2 6.9 8.6 15 5.7 8.6 1.6 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-C2H2_aberr PF17017.5 PVD35675.1 - 3.5e-06 27.3 1.4 0.0001 22.5 0.2 2.2 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 PVD35675.1 - 0.00089 19.9 7.8 0.056 14.3 1.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD35675.1 - 0.02 14.9 1.9 0.02 14.9 1.9 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 PVD35675.1 - 0.13 12.9 0.9 4 8.2 0.0 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 PVD35675.1 - 0.18 12.3 8.4 2.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 PVD35675.1 - 0.26 11.8 8.8 3.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ig_3 PF13927.6 PVD35676.1 - 8.1e-53 176.9 0.1 8.6e-12 45.5 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 PVD35676.1 - 9.7e-42 141.2 1.0 4e-09 36.7 0.0 6.7 4 1 2 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD35676.1 - 1.1e-41 140.8 0.0 8.1e-12 45.1 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 PVD35676.1 - 6.3e-27 93.6 0.0 4.8e-05 23.5 0.0 6.6 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 PVD35676.1 - 3e-25 88.4 1.5 2.1e-08 34.4 0.1 4.8 4 0 0 4 4 4 4 Fibronectin type III domain DnaJ PF00226.31 PVD35676.1 - 1.2e-11 44.5 0.1 2.8e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain V-set PF07686.17 PVD35676.1 - 1.1e-09 38.5 9.7 0.046 13.9 0.1 8.9 6 5 0 7 7 7 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD35676.1 - 3.4e-09 36.1 0.1 0.02 14.5 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Ig_5 PF16681.5 PVD35676.1 - 0.00051 20.4 0.4 2 8.9 0.0 5.1 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 PVD35676.1 - 0.00061 19.8 0.1 11 6.1 0.0 3.8 3 0 0 3 3 3 1 C17orf99 Ig domain Izumo-Ig PF16706.5 PVD35676.1 - 0.017 15.2 0.2 5.6 7.1 0.0 4.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 PVD35676.1 - 0.03 14.3 0.0 2.3 8.3 0.0 3.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 PVD35676.1 - 0.031 14.5 0.0 29 4.9 0.0 4.1 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 PVD35676.1 - 0.1 12.7 0.1 32 4.7 0.0 3.2 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain DUF4407 PF14362.6 PVD35676.1 - 0.78 9.0 5.2 1.1 8.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SH3BP5 PF05276.14 PVD35677.1 - 3.3e-90 301.9 22.4 3.3e-90 301.9 22.4 1.7 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Tropomyosin_1 PF12718.7 PVD35677.1 - 0.00036 20.7 6.5 0.00036 20.7 6.5 2.6 2 0 0 2 2 2 1 Tropomyosin like DUF1351 PF07083.11 PVD35677.1 - 0.55 10.0 10.1 0.81 9.4 9.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) WASH-7_C PF14746.6 PVD35677.1 - 1.2 8.9 4.7 0.41 10.3 0.1 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Perilipin PF03036.16 PVD35677.1 - 1.7 7.6 11.5 2.8 6.9 11.5 1.3 1 0 0 1 1 1 0 Perilipin family AAA_17 PF13207.6 PVD35677.1 - 2.2 8.7 5.7 1.4 9.3 3.2 2.0 2 0 0 2 2 2 0 AAA domain PID PF00640.23 PVD35678.1 - 1.2e-28 99.9 0.0 2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD35678.1 - 3.8e-13 49.7 0.0 6.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 PVD35678.1 - 1.2e-07 31.8 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) bZIP_1 PF00170.21 PVD35678.1 - 0.012 15.7 2.0 0.021 14.9 2.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 PVD35678.1 - 0.034 14.6 4.9 0.061 13.8 4.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF4699 PF15770.5 PVD35678.1 - 0.11 12.3 1.7 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) NEMO PF11577.8 PVD35678.1 - 0.12 12.4 3.0 0.26 11.3 3.0 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO GIT_CC PF16559.5 PVD35678.1 - 0.13 12.2 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 PVD35678.1 - 0.17 12.0 3.3 0.3 11.2 3.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 PVD35678.1 - 0.27 11.0 3.5 0.51 10.1 3.5 1.4 1 0 0 1 1 1 0 Septum formation initiator PID PF00640.23 PVD35679.1 - 2.3e-24 86.0 0.0 6.7e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 PVD35679.1 - 1.1e-11 45.0 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 PVD35679.1 - 9.7e-09 35.3 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) bZIP_1 PF00170.21 PVD35679.1 - 0.089 12.9 1.4 0.18 11.9 1.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 PVD35679.1 - 0.14 12.1 0.3 0.37 10.7 0.3 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 PVD35679.1 - 0.25 11.5 1.5 0.45 10.6 1.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Chlam_OMP3 PF03503.13 PVD35679.1 - 1.3 9.4 4.6 0.54 10.6 1.8 1.9 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 STAT_bind PF02864.15 PVD35680.1 - 7.1e-50 169.0 0.1 7.1e-50 169.0 0.1 2.7 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 PVD35680.1 - 2.5e-40 138.2 19.8 5.4e-40 137.1 19.8 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.17 PVD35680.1 - 1.4e-26 93.4 0.2 1.4e-26 93.4 0.2 3.2 2 1 1 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.24 PVD35680.1 - 1.2e-08 35.0 0.0 6.1e-08 32.7 0.0 2.2 1 0 0 1 1 1 1 SH2 domain STATa_Ig PF18214.1 PVD35680.1 - 0.004 17.2 2.2 0.015 15.3 0.1 2.4 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain Efg1 PF10153.9 PVD35680.1 - 3.3 8.1 10.9 8.1 6.8 10.9 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 SelP_N PF04592.14 PVD35681.1 - 0.0048 16.3 4.9 0.0048 16.3 4.9 2.2 2 0 0 2 2 2 1 Selenoprotein P, N terminal region DUF2456 PF10445.9 PVD35683.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Rpn3_C PF08375.11 PVD35684.1 - 8.1e-29 99.9 1.7 8.1e-29 99.9 1.7 2.7 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 PVD35684.1 - 3e-24 85.6 0.0 2.3e-23 82.7 0.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 PVD35684.1 - 0.0015 18.5 1.4 0.0068 16.4 1.4 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3510 PF12022.8 PVD35684.1 - 0.025 15.0 0.1 0.074 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) CSN8_PSD8_EIF3K PF10075.9 PVD35684.1 - 0.035 14.1 0.1 0.26 11.3 0.0 2.4 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family EH_Signature PF15611.6 PVD35684.1 - 0.1 12.0 3.2 0.75 9.1 3.2 2.1 1 1 0 1 1 1 0 EH_Signature domain Pro-MCH PF05824.12 PVD35684.1 - 0.58 10.1 2.8 0.45 10.5 0.3 2.2 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) TPR_14 PF13428.6 PVD35684.1 - 3.5 8.7 6.0 61 4.8 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat ORC2 PF04084.14 PVD35685.1 - 1.7e-71 240.9 1.0 3.3e-71 239.9 1.0 1.5 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Pkinase PF00069.25 PVD35685.1 - 5.6e-69 232.4 0.0 9e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD35685.1 - 2.9e-32 112.0 0.0 5.4e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD35685.1 - 2.6e-05 23.7 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD35685.1 - 0.0007 19.0 0.1 0.0022 17.4 0.1 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 PVD35685.1 - 0.0021 17.7 0.0 0.0071 16.0 0.0 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PVD35685.1 - 0.0046 16.9 1.8 0.046 13.7 0.0 2.8 3 1 1 4 4 4 1 Phosphotransferase enzyme family Wx5_PLAF3D7 PF09688.10 PVD35685.1 - 0.56 10.2 2.7 6.5 6.7 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) VWD PF00094.25 PVD35686.1 - 2.9e-48 164.1 0.8 6.9e-28 97.9 0.2 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain Lectin_C PF00059.21 PVD35686.1 - 2.1e-21 76.7 0.9 0.00064 20.4 0.0 7.1 6 0 0 6 6 6 4 Lectin C-type domain WSC PF01822.19 PVD35686.1 - 2e-16 59.9 10.1 2e-16 59.9 10.1 6.9 7 1 2 9 9 9 1 WSC domain C8 PF08742.11 PVD35686.1 - 2.1e-14 53.7 5.7 2.1e-14 53.7 5.7 6.3 5 1 1 6 6 6 1 C8 domain EGF_CA PF07645.15 PVD35686.1 - 9.9e-10 38.5 25.8 2.7e-08 33.9 5.3 11.7 10 2 1 11 11 11 3 Calcium-binding EGF domain cEGF PF12662.7 PVD35686.1 - 2.2e-05 24.3 0.5 2.2e-05 24.3 0.5 9.3 8 0 0 8 8 8 3 Complement Clr-like EGF-like MRP-S27 PF10037.9 PVD35687.1 - 1.1e-87 294.4 5.7 1.4e-87 294.2 5.7 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 VWA_2 PF13519.6 PVD35687.1 - 0.041 14.5 0.4 0.1 13.2 0.1 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Ig_3 PF13927.6 PVD35688.1 - 1.1e-64 214.9 7.9 2.3e-14 53.7 0.6 6.8 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 PVD35688.1 - 6.3e-53 176.8 0.0 3.9e-14 52.5 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD35688.1 - 2.2e-52 175.3 4.7 2.8e-09 37.2 0.2 6.7 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 PVD35688.1 - 3.1e-40 136.2 1.1 1.2e-07 31.8 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 PVD35688.1 - 3e-25 88.4 3.1 6.3e-10 39.3 0.1 5.7 5 0 0 5 5 5 4 Fibronectin type III domain V-set PF07686.17 PVD35688.1 - 3.2e-12 46.6 10.6 0.11 12.7 0.1 8.1 6 4 3 9 9 9 4 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD35688.1 - 1.1e-07 32.1 0.0 0.19 12.2 0.0 4.5 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD35688.1 - 2.9e-07 29.9 0.1 4.7 6.8 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 PVD35688.1 - 1.2e-06 28.7 0.2 0.68 10.2 0.0 4.4 5 0 0 5 5 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 PVD35688.1 - 1.6e-06 28.1 0.4 0.12 12.4 0.0 4.6 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 PVD35688.1 - 0.00017 21.9 0.4 0.079 13.3 0.1 4.5 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 PVD35688.1 - 0.00038 20.5 1.3 4.3 7.5 0.0 5.2 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD35688.1 - 0.0027 17.7 0.2 1.5 8.9 0.1 4.5 5 0 0 5 5 5 1 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 PVD35688.1 - 0.0045 16.7 1.9 4.9 7.0 0.0 4.3 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 Lectin_C PF00059.21 PVD35688.1 - 0.032 15.0 0.0 0.21 12.3 0.0 2.4 3 0 0 3 3 1 0 Lectin C-type domain PKD_3 PF16820.5 PVD35688.1 - 0.035 13.9 0.0 0.26 11.1 0.0 2.6 1 0 0 1 1 1 0 PKD-like domain PKD PF00801.20 PVD35688.1 - 0.096 12.5 4.8 0.12 12.2 1.4 2.8 3 0 0 3 3 3 0 PKD domain Xan_ur_permease PF00860.20 PVD35689.1 - 3.2e-65 220.3 20.5 1.4e-64 218.2 20.5 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 PVD35689.1 - 0.016 15.6 6.1 0.016 15.6 6.1 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 PVD35692.1 - 2.7e-86 289.7 31.9 2.7e-86 289.7 31.9 2.1 4 0 0 4 4 4 1 Permease family Acyl_transf_3 PF01757.22 PVD35692.1 - 4.6e-10 39.1 34.8 1.4e-09 37.5 13.0 4.0 3 1 1 4 4 4 2 Acyltransferase family DUF3382 PF11862.8 PVD35692.1 - 4.6 7.6 11.1 0.24 11.7 2.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) MFS_MOT1 PF16983.5 PVD35692.1 - 6 7.3 21.4 0.031 14.7 3.4 4.5 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily Acyl_transf_3 PF01757.22 PVD35693.1 - 1.6e-33 116.2 67.1 5e-21 75.1 37.3 3.4 2 1 0 2 2 2 2 Acyltransferase family Gemini_mov PF01708.16 PVD35693.1 - 0.016 14.9 0.0 0.98 9.2 0.0 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein Acyl_transf_3 PF01757.22 PVD35695.1 - 2.4e-12 46.6 25.3 3.1e-12 46.2 25.3 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF1011 PF06237.12 PVD35695.1 - 1.7 9.1 7.4 0.35 11.2 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1011) Acyl_transf_3 PF01757.22 PVD35696.1 - 8.3e-34 117.2 85.4 1.2e-22 80.5 36.8 3.4 2 1 0 2 2 2 2 Acyltransferase family Gemini_mov PF01708.16 PVD35696.1 - 0.0055 16.4 0.1 4.4 7.1 0.0 3.2 3 0 0 3 3 3 2 Geminivirus putative movement protein DUF1298 PF06974.13 PVD35696.1 - 0.091 12.7 0.5 16 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) DUF3930 PF13067.6 PVD35696.1 - 1.4 9.2 3.8 32 4.9 0.7 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3930) ATP19 PF11022.8 PVD35696.1 - 1.7 9.1 4.8 39 4.7 0.3 4.1 4 0 0 4 4 4 0 ATP synthase subunit K Translin PF01997.16 PVD35697.1 - 3.3e-44 151.3 0.1 5.4e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Translin family Acyl_transf_3 PF01757.22 PVD35697.1 - 1.5e-22 80.1 36.5 2.7e-22 79.3 36.5 1.3 1 0 0 1 1 1 1 Acyltransferase family Laminin_EGF PF00053.24 PVD35698.1 - 1.7e-31 108.1 439.0 3.5e-05 23.9 10.9 24.5 9 3 14 23 23 23 17 Laminin EGF domain Laminin_G_3 PF13385.6 PVD35698.1 - 1.1e-15 58.1 0.2 2.7e-15 56.8 0.2 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 PVD35698.1 - 0.0056 17.0 17.3 0.0056 17.0 17.3 33.0 26 10 3 29 29 29 12 EGF-like domain V_ATPase_I PF01496.19 PVD35699.1 - 4.2e-293 974.3 0.1 4.2e-293 974.3 0.1 4.8 4 1 1 5 5 5 1 V-type ATPase 116kDa subunit family YolD PF08863.10 PVD35699.1 - 0.043 13.9 5.0 0.22 11.6 5.0 2.3 1 0 0 1 1 1 0 YolD-like protein Mito_carr PF00153.27 PVD35701.1 - 8.3e-70 230.8 2.4 1.1e-22 79.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Tetraspanin PF00335.20 PVD35702.1 - 6.4e-09 35.9 4.7 7.5e-09 35.6 4.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3493 PF11998.8 PVD35702.1 - 0.037 14.2 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Galactosyl_T PF01762.21 PVD35707.1 - 4.4e-51 173.5 0.3 6.7e-51 172.9 0.3 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD35707.1 - 0.00056 19.4 0.2 0.0012 18.4 0.1 1.7 2 0 0 2 2 2 1 Fringe-like Peptidase_M26_N PF05342.14 PVD35707.1 - 0.044 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Complex1_LYR_2 PF13233.6 PVD35708.1 - 0.012 16.4 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Ins_beta PF03488.14 PVD35709.1 - 0.0045 17.0 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Nematode insulin-related peptide beta type Na_Pi_cotrans PF02690.15 PVD35711.1 - 1.2e-28 99.9 14.2 4.2e-25 88.5 4.1 2.5 2 1 0 2 2 2 2 Na+/Pi-cotransporter Na_Pi_cotrans PF02690.15 PVD35712.1 - 4.4e-35 120.8 13.5 4.4e-22 78.7 2.6 2.7 3 0 0 3 3 3 2 Na+/Pi-cotransporter PRT_C PF08372.10 PVD35712.1 - 0.095 12.5 2.4 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Tetraspanin PF00335.20 PVD35712.1 - 9.7 5.8 11.9 0.055 13.2 0.8 2.6 2 1 0 2 2 2 0 Tetraspanin family Na_Pi_cotrans PF02690.15 PVD35713.1 - 1.8e-40 138.3 14.6 2.8e-25 89.0 4.1 2.5 2 0 0 2 2 2 2 Na+/Pi-cotransporter DUF2101 PF09874.9 PVD35713.1 - 5 6.8 11.1 17 5.0 11.1 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) IQ PF00612.27 PVD35714.1 - 3e-13 48.3 11.3 0.0011 18.5 0.2 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif PerC PF06069.11 PVD35714.1 - 0.15 12.4 3.8 27 5.1 0.4 3.5 3 0 0 3 3 3 0 PerC transcriptional activator TetR_C_13 PF16925.5 PVD35714.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M18 PF02127.15 PVD35715.1 - 7.1e-171 568.8 0.0 8.8e-171 568.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 PVD35715.1 - 2.9e-05 23.3 0.1 0.0001 21.5 0.2 1.7 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase FYRC PF05965.14 PVD35716.1 - 3.8e-22 78.2 0.0 1.5e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus SET PF00856.28 PVD35716.1 - 7.4e-21 75.3 2.2 2.3e-20 73.7 0.3 2.5 2 0 0 2 2 2 1 SET domain FYRN PF05964.14 PVD35716.1 - 9.5e-18 63.8 1.2 1.9e-17 62.8 1.2 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H_2 PF13832.6 PVD35716.1 - 1.1e-10 41.6 5.2 2.6e-10 40.4 5.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PVD35716.1 - 9.8e-10 38.6 8.2 2.4e-09 37.3 8.2 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 PVD35718.1 - 4e-39 132.3 108.7 2e-09 37.2 7.6 7.8 5 2 2 7 7 7 6 PHD-finger zf-HC5HC2H PF13771.6 PVD35718.1 - 8.4e-08 32.4 3.6 8.4e-08 32.4 3.6 7.4 4 2 2 7 7 7 1 PHD-like zinc-binding domain HMG_box PF00505.19 PVD35718.1 - 2.5e-07 31.0 2.3 6.9e-07 29.6 2.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD35718.1 - 0.0043 17.6 1.0 0.016 15.8 1.0 1.9 1 0 0 1 1 1 1 HMG-box domain V_ATPase_I PF01496.19 PVD35718.1 - 8 4.2 13.1 13 3.5 13.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EGF PF00008.27 PVD35719.1 - 1.1e-31 108.7 71.0 1.3e-08 34.9 7.1 6.6 5 1 1 6 6 6 6 EGF-like domain hEGF PF12661.7 PVD35719.1 - 1.3e-13 51.0 75.8 2.3e-06 28.0 6.0 8.2 8 1 0 8 8 8 6 Human growth factor-like EGF EGF_2 PF07974.13 PVD35719.1 - 3.7e-11 43.2 77.5 0.0014 18.9 11.3 6.7 6 0 0 6 6 6 5 EGF-like domain EGF_3 PF12947.7 PVD35719.1 - 0.027 14.7 4.3 0.027 14.7 4.3 6.2 4 2 2 6 6 6 0 EGF domain FXa_inhibition PF14670.6 PVD35719.1 - 2.6 8.4 63.7 2 8.7 5.6 6.4 2 2 3 5 5 5 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD35720.1 - 9.7e-46 153.7 142.2 6.2e-09 36.0 8.4 11.1 10 1 0 10 10 10 10 EGF-like domain hEGF PF12661.7 PVD35720.1 - 4.5e-28 96.9 124.5 1.4e-06 28.7 5.0 13.0 12 0 0 12 12 12 9 Human growth factor-like EGF EGF_2 PF07974.13 PVD35720.1 - 9.4e-16 57.9 174.8 0.0018 18.6 5.0 10.6 8 2 2 10 10 10 10 EGF-like domain EGF_CA PF07645.15 PVD35720.1 - 0.0065 16.6 11.7 0.0065 16.6 11.7 11.2 1 1 9 10 10 10 6 Calcium-binding EGF domain Laminin_EGF PF00053.24 PVD35720.1 - 0.42 10.8 141.0 0.69 10.1 4.6 11.0 1 1 9 10 10 10 0 Laminin EGF domain EGF_3 PF12947.7 PVD35720.1 - 0.46 10.7 137.5 0.13 12.5 10.8 11.3 10 1 0 10 10 10 0 EGF domain EGF PF00008.27 PVD35721.1 - 2.2e-13 50.3 41.9 7.5e-07 29.3 6.9 4.6 4 0 0 4 4 4 3 EGF-like domain DSL PF01414.19 PVD35721.1 - 2.5e-10 40.5 0.3 2.5e-10 40.5 0.3 3.1 2 1 1 3 3 3 2 Delta serrate ligand hEGF PF12661.7 PVD35721.1 - 0.0017 18.9 13.7 0.0036 17.9 3.7 5.7 6 1 0 6 6 6 3 Human growth factor-like EGF EGF_2 PF07974.13 PVD35721.1 - 5 7.6 49.1 0.067 13.6 8.8 4.7 5 0 0 5 5 5 0 EGF-like domain Peptidase_M2 PF01401.18 PVD35723.1 - 5.3e-171 570.1 0.9 2.3e-135 452.4 0.0 2.0 1 1 1 2 2 2 2 Angiotensin-converting enzyme DSS1_SEM1 PF05160.13 PVD35724.1 - 5.7e-24 84.0 19.0 6.8e-24 83.7 19.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 PVD35724.1 - 0.048 13.5 4.8 0.057 13.3 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DNA_pol_phi PF04931.13 PVD35724.1 - 6.6 4.7 11.6 7.4 4.5 11.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi FlaC_arch PF05377.11 PVD35725.1 - 0.016 15.6 1.5 0.016 15.6 1.5 7.8 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) RIC3 PF15361.6 PVD35725.1 - 0.21 12.0 0.1 0.21 12.0 0.1 6.1 4 2 0 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 Mating_N PF12731.7 PVD35725.1 - 1.7 8.8 13.3 1.3 9.2 0.5 5.1 5 0 0 5 5 5 0 Mating-type protein beta 1 TrbC PF04956.13 PVD35726.1 - 0.081 13.1 0.1 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family Ribosomal_S20p PF01649.18 PVD35727.1 - 0.033 14.8 0.4 0.11 13.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S20 Sulfatase PF00884.23 PVD35728.1 - 3e-69 233.8 4.9 9.7e-62 209.1 1.5 3.2 2 1 1 3 3 3 3 Sulfatase DUF4994 PF16385.5 PVD35728.1 - 3.4e-05 23.7 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function Phosphodiest PF01663.22 PVD35728.1 - 0.0018 18.0 0.8 0.03 13.9 0.8 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 PVD35728.1 - 0.0045 17.7 0.3 5.6 7.7 0.0 3.1 3 0 0 3 3 3 2 C-terminal region of aryl-sulfatase RNA_pol_Rpb2_1 PF04563.15 PVD35728.1 - 0.019 14.5 0.4 5.1 6.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase beta subunit BBIP10 PF14777.6 PVD35728.1 - 7.9 6.1 7.1 16 5.1 1.5 2.4 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 AI-2E_transport PF01594.16 PVD35729.1 - 3.5e-08 33.0 19.8 3.5e-08 33.0 19.8 5.4 4 2 1 5 5 5 3 AI-2E family transporter PNP_UDP_1 PF01048.20 PVD35730.1 - 4.3e-17 62.2 0.0 8.3e-17 61.2 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily RUN PF02759.19 PVD35731.1 - 8.3e-20 71.1 4.2 1.1e-19 70.7 0.0 2.7 2 1 0 2 2 2 1 RUN domain MRP-L28 PF09812.9 PVD35731.1 - 1 9.4 13.7 0.057 13.6 8.1 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 BTB PF00651.31 PVD35732.1 - 1.7e-13 50.8 2.5 2.6e-12 46.9 2.5 2.6 1 1 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 PVD35732.1 - 1.2e-08 35.1 0.2 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 PVD35732.1 - 0.003 17.6 0.4 0.059 13.5 0.0 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch DUF4580 PF15162.6 PVD35733.1 - 1.9e-17 63.3 0.1 2.5e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) PTPS PF01242.19 PVD35733.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.6 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase EB PF01683.18 PVD35734.1 - 1.2e-70 233.7 366.0 0.00022 21.4 4.7 29.3 5 3 23 28 28 28 24 EB module EGF_CA PF07645.15 PVD35734.1 - 4.2e-07 30.1 0.8 4.2e-07 30.1 0.8 27.7 26 4 3 29 29 29 1 Calcium-binding EGF domain EGF_3 PF12947.7 PVD35734.1 - 2.7e-05 24.3 0.8 2.7e-05 24.3 0.8 27.3 25 3 3 28 28 28 2 EGF domain Ldl_recept_a PF00057.18 PVD35734.1 - 0.00018 21.7 3.6 0.00018 21.7 3.6 21.0 22 4 3 25 25 25 3 Low-density lipoprotein receptor domain class A cEGF PF12662.7 PVD35734.1 - 0.15 12.0 180.7 0.044 13.7 1.7 24.3 25 0 0 25 25 25 0 Complement Clr-like EGF-like 7tm_1 PF00001.21 PVD35736.1 - 3.1e-13 49.7 6.9 5e-13 49.0 6.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD35736.1 - 3.1e-10 39.9 5.0 4e-10 39.5 5.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD35736.1 - 1.7e-06 27.6 4.2 1.7e-06 27.6 4.2 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD35736.1 - 7.5e-06 25.8 6.3 1e-05 25.3 6.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD35736.1 - 0.00018 21.3 1.6 0.00027 20.8 1.6 1.2 1 0 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 PVD35736.1 - 0.02 14.8 2.9 0.035 14.1 2.9 1.4 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srz PF10325.9 PVD35736.1 - 0.059 12.7 2.4 0.075 12.3 2.0 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Srg PF02118.21 PVD35736.1 - 4.6 6.8 11.4 22 4.6 11.4 1.9 1 1 0 1 1 1 0 Srg family chemoreceptor 7tm_1 PF00001.21 PVD35737.1 - 2.4e-09 36.9 4.3 3.2e-09 36.5 4.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sri PF10327.9 PVD35737.1 - 0.00077 18.7 4.4 0.001 18.4 4.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri TctB PF07331.11 PVD35737.1 - 0.0057 16.9 0.9 0.0073 16.6 0.9 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family CopD PF05425.13 PVD35737.1 - 0.02 15.3 0.4 0.033 14.6 0.4 1.3 1 0 0 1 1 1 0 Copper resistance protein D DUF4173 PF13777.6 PVD35737.1 - 0.028 13.8 2.7 0.031 13.7 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF2700 PF10912.8 PVD35737.1 - 0.028 14.4 2.9 0.045 13.8 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2700) AveC_like PF17198.4 PVD35737.1 - 0.029 13.8 1.7 0.033 13.6 1.0 1.4 1 1 0 1 1 1 0 Spirocyclase AveC-like DUF3169 PF11368.8 PVD35737.1 - 0.13 11.8 3.9 0.44 10.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Pal1 PF08316.11 PVD35738.1 - 0.23 12.2 0.7 0.27 12.0 0.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein NPR3 PF03666.13 PVD35738.1 - 0.24 10.1 8.6 0.31 9.8 8.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PVD35738.1 - 0.27 10.0 4.2 0.28 9.9 4.2 1.0 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 PVD35738.1 - 0.34 9.6 3.8 0.38 9.5 3.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3464 PF11947.8 PVD35738.1 - 0.57 9.9 4.5 0.68 9.7 4.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 HAUS6_N PF14661.6 PVD35738.1 - 0.59 9.7 7.2 0.71 9.4 7.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FemAB PF02388.16 PVD35738.1 - 1.2 7.9 6.6 1.4 7.8 6.6 1.0 1 0 0 1 1 1 0 FemAB family NARP1 PF12569.8 PVD35738.1 - 1.3 7.8 9.8 1.4 7.7 9.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.10 PVD35738.1 - 1.5 9.1 13.0 1.9 8.8 13.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 PVD35738.1 - 4.2 7.1 12.5 5 6.9 12.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 PVD35738.1 - 6.7 4.9 15.5 7.5 4.7 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3987 PF13148.6 PVD35738.1 - 8.9 5.2 11.9 11 4.9 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YqfQ PF14181.6 PVD35738.1 - 9.9 6.3 7.6 13 6.0 7.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2794 PF10984.8 PVD35739.1 - 0.03 14.5 0.3 0.059 13.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2794) Presenilin PF01080.17 PVD35739.1 - 0.43 9.3 2.3 0.49 9.1 2.3 1.0 1 0 0 1 1 1 0 Presenilin BAR PF03114.18 PVD35740.1 - 1.8e-31 109.6 11.9 2.8e-31 109.0 11.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 PVD35740.1 - 1.7e-10 40.6 0.1 3.4e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD35740.1 - 1.5e-07 30.9 0.4 3.6e-07 29.7 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD35740.1 - 1.4e-06 27.9 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Streptin-Immun PF11083.8 PVD35740.1 - 0.059 13.8 2.0 1.7 9.1 0.6 2.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DUF948 PF06103.11 PVD35740.1 - 0.16 12.2 4.2 0.096 13.0 1.1 2.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Metal_resist PF13801.6 PVD35740.1 - 0.18 12.0 0.4 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Heavy-metal resistance UPF0242 PF06785.11 PVD35740.1 - 0.37 10.9 14.1 0.032 14.3 5.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5638 PF18688.1 PVD35740.1 - 0.98 9.8 7.0 0.19 12.0 2.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF1664 PF07889.12 PVD35740.1 - 2.3 8.3 10.7 0.26 11.3 2.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) TssC PF17541.2 PVD35740.1 - 2.7 6.7 10.5 0.19 10.5 3.9 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB Arfaptin PF06456.13 PVD35740.1 - 3.4 7.2 14.1 7.1 6.1 11.1 2.6 1 1 1 2 2 2 0 Arfaptin-like domain PilJ PF13675.6 PVD35740.1 - 4.5 7.3 6.6 0.82 9.7 0.6 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spectrin PF00435.21 PVD35740.1 - 6.2 7.4 11.3 1.6 9.2 5.4 2.6 2 1 1 3 3 3 0 Spectrin repeat Wx5_PLAF3D7 PF09688.10 PVD35740.1 - 9.8 6.2 9.6 2.3 8.2 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Cpn60_TCP1 PF00118.24 PVD35741.1 - 5.8e-155 516.6 5.0 7.2e-155 516.3 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lectin_C PF00059.21 PVD35743.1 - 1.5e-07 32.1 0.2 0.0004 21.1 0.0 3.1 3 0 0 3 3 3 2 Lectin C-type domain RRM_1 PF00076.22 PVD35744.1 - 7e-38 128.3 0.1 4.2e-18 64.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD35744.1 - 3.5e-12 46.3 0.1 6.1e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD35744.1 - 2.8e-05 24.0 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PVD35744.1 - 0.0047 17.0 0.1 0.03 14.4 0.1 2.1 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM PF05172.13 PVD35744.1 - 0.12 12.4 0.0 5.1 7.1 0.0 2.6 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 PVD35745.1 - 1e-22 79.7 0.4 6.7e-12 45.0 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD35745.1 - 1.2e-07 31.7 0.1 0.0051 16.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif Chromo_shadow PF01393.19 PVD35746.1 - 5.8e-30 103.1 0.0 1.2e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 PVD35746.1 - 1.4e-07 31.3 0.8 0.00031 20.6 0.3 2.8 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain A_deamin PF02137.18 PVD35747.1 - 6.5e-107 357.8 0.0 1.5e-106 356.5 0.0 1.6 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 PVD35747.1 - 9e-35 119.2 0.7 1.6e-13 51.2 0.0 3.7 3 0 0 3 3 3 3 Double-stranded RNA binding motif IgG_binding_B PF01378.17 PVD35747.1 - 1.3 9.1 3.7 0.72 10.0 0.4 2.3 2 0 0 2 2 2 0 B domain DND1_DSRM PF14709.7 PVD35747.1 - 1.5 9.1 4.4 15 6.0 0.3 3.8 4 1 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.32 PVD35748.1 - 4e-30 103.4 19.2 2.7e-07 31.2 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD35748.1 - 0.00031 21.0 0.1 0.69 10.3 0.0 3.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 PVD35748.1 - 0.13 12.5 0.4 25 5.3 0.1 2.7 2 0 0 2 2 2 0 Tup N-terminal Rtf2 PF04641.12 PVD35753.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger YjzC PF14168.6 PVD35754.1 - 0.022 15.1 0.3 0.045 14.1 0.3 1.5 1 0 0 1 1 1 0 YjzC-like protein Glyco_transf_11 PF01531.16 PVD35756.1 - 1.4e-25 90.1 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 DUF4503 PF14951.6 PVD35756.1 - 0.014 13.9 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) O-FucT PF10250.9 PVD35756.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase 7tm_1 PF00001.21 PVD35757.1 - 5.7e-32 111.1 3.1 7.7e-32 110.6 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD35757.1 - 2.8e-05 23.9 11.2 6.6e-05 22.7 11.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD35757.1 - 8.5e-05 22.1 4.9 0.00012 21.5 4.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD35757.1 - 0.0017 18.1 0.4 0.0017 18.1 0.4 1.6 2 0 0 2 2 2 1 Olfactory receptor CcmH PF03918.14 PVD35757.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Stathmin PF00836.19 PVD35758.1 - 9.9e-13 48.2 18.2 9.9e-13 48.2 18.2 1.9 2 0 0 2 2 2 1 Stathmin family Caldesmon PF02029.15 PVD35758.1 - 0.026 13.3 30.1 0.034 12.9 30.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF1870 PF08965.10 PVD35758.1 - 1.4 8.9 4.8 2.9 8.0 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) UPF0242 PF06785.11 PVD35758.1 - 3.1 7.9 13.5 6.3 6.9 13.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase_Tyr PF07714.17 PVD35760.1 - 7.8e-94 313.8 0.0 1e-93 313.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35760.1 - 1.2e-46 159.3 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD35760.1 - 2.2e-25 88.5 0.1 4.6e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD35760.1 - 3.2e-16 58.7 0.2 1.4e-15 56.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 PVD35760.1 - 2.6e-11 43.2 0.1 8.1e-11 41.6 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD35760.1 - 4.1e-10 39.2 0.0 1.4e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 PVD35760.1 - 0.00092 19.2 0.0 0.0087 16.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD35760.1 - 0.002 17.1 0.0 0.0036 16.3 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain BssC_TutF PF08201.11 PVD35760.1 - 0.0096 15.9 3.1 0.51 10.4 0.1 3.1 3 0 0 3 3 3 1 BssC/TutF protein hSH3 PF14603.6 PVD35760.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_10 PF17902.1 PVD35760.1 - 0.039 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 PVD35760.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 PVD35760.1 - 0.046 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_Tyr PF07714.17 PVD35761.1 - 1.8e-84 283.1 0.0 2.3e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35761.1 - 4.2e-47 160.7 0.0 6.9e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD35761.1 - 2.8e-05 24.1 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD35761.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 PVD35761.1 - 0.00031 19.8 0.0 0.00045 19.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD35761.1 - 0.0068 16.4 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD35761.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SH3_9 PF14604.6 PVD35761.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Pkinase_Tyr PF07714.17 PVD35762.1 - 1.2e-85 287.0 0.0 1.5e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35762.1 - 1.5e-43 149.1 0.0 2.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD35762.1 - 1.4e-15 57.1 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD35762.1 - 3.8e-15 55.2 1.6 3.5e-13 48.9 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PVD35762.1 - 2.2e-11 43.4 0.8 3.7e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PVD35762.1 - 2.9e-06 26.9 0.1 8.9e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 PVD35762.1 - 0.0014 17.6 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD35762.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PVD35762.1 - 0.056 13.4 0.1 0.33 10.8 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PVD35763.1 - 1e-77 261.0 0.1 2e-77 260.0 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35763.1 - 1.7e-43 148.9 0.0 5.9e-43 147.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PVD35763.1 - 2.7e-16 59.4 0.0 4.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 PVD35763.1 - 5.2e-14 51.6 0.1 5.2e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 PVD35763.1 - 2.4e-11 43.3 0.2 1e-10 41.3 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PVD35763.1 - 5.9e-07 29.1 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 PVD35763.1 - 1.4e-05 24.2 0.1 2.7e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD35763.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD35763.1 - 0.022 14.7 0.2 0.088 12.7 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD35763.1 - 0.082 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_10 PF17902.1 PVD35763.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain RICTOR_N PF14664.6 PVD35764.1 - 1.3e-95 320.6 0.9 1.3e-95 320.6 0.9 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 PVD35764.1 - 1.1e-34 119.1 7.5 3e-34 117.7 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 PVD35764.1 - 6.6e-29 100.0 0.8 3.4e-27 94.5 0.1 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 PVD35764.1 - 5.8e-24 83.8 3.7 4.6e-22 77.8 0.2 3.9 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain HEAT_EZ PF13513.6 PVD35764.1 - 0.14 12.7 0.1 50 4.5 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat SGL PF08450.12 PVD35765.1 - 1.1e-32 113.6 0.0 1.3e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 PVD35765.1 - 0.13 12.4 0.0 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Strictosidine synthase Reg_prop PF07494.11 PVD35765.1 - 0.15 12.4 0.0 64 4.3 0.0 3.6 4 0 0 4 4 4 0 Two component regulator propeller SBBP PF06739.11 PVD35765.1 - 5.9 7.0 4.9 9.6 6.3 0.0 3.7 5 0 0 5 5 5 0 Beta-propeller repeat ATP-synt_DE_N PF02823.16 PVD35766.1 - 7e-18 64.3 0.0 1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain UCR_hinge PF02320.16 PVD35767.1 - 5.4e-18 65.0 11.1 2.7e-17 62.7 11.1 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 PVD35767.1 - 0.085 13.1 5.5 0.23 11.7 5.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 PVD35767.1 - 1.8 8.8 9.9 11 6.4 9.9 2.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb MCLC PF05934.11 PVD35768.1 - 3.1e-19 69.1 4.7 3.4e-18 65.7 4.2 2.1 1 1 0 1 1 1 1 Mid-1-related chloride channel (MCLC) TMIE PF16038.5 PVD35768.1 - 0.16 11.9 4.9 0.11 12.3 2.2 2.2 2 0 0 2 2 2 0 TMIE protein Shisa PF13908.6 PVD35768.1 - 2.8 8.1 7.3 0.25 11.6 0.7 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator URO-D PF01208.17 PVD35769.1 - 2e-86 290.3 0.0 2.2e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Spc7 PF08317.11 PVD35770.1 - 0.0014 17.5 13.1 0.0017 17.3 13.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4988 PF16378.5 PVD35770.1 - 0.012 15.3 1.0 0.018 14.7 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function FAM76 PF16046.5 PVD35770.1 - 0.069 12.5 7.2 0.076 12.4 7.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1269 PF06897.12 PVD35770.1 - 0.42 10.9 2.0 14 6.0 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1269) NPV_P10 PF05531.12 PVD35770.1 - 0.71 10.4 6.0 1.2 9.7 1.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ASF1_hist_chap PF04729.13 PVD35771.1 - 2.8e-53 180.0 0.0 3.9e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DEAD PF00270.29 PVD35772.1 - 4.9e-54 182.7 0.0 7.1e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 PVD35772.1 - 2.6e-33 112.6 54.0 2.4e-07 30.5 3.9 5.6 5 0 0 5 5 5 5 Zinc knuckle Helicase_C PF00271.31 PVD35772.1 - 4.7e-32 110.6 0.0 5.1e-31 107.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC_3 PF13917.6 PVD35772.1 - 6.2e-13 48.5 29.9 0.0092 15.9 1.4 5.8 3 1 3 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 PVD35772.1 - 3.3e-11 42.8 39.8 0.00022 21.0 2.2 5.6 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 PVD35772.1 - 5.2e-05 22.9 39.7 0.023 14.4 2.9 5.5 5 0 0 5 5 5 5 GAG-polyprotein viral zinc-finger ResIII PF04851.15 PVD35772.1 - 0.0029 17.6 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PVD35772.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEM4 PF02602.15 PVD35772.1 - 0.071 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD UTP25 PF06862.12 PVD35772.1 - 0.21 10.3 0.0 1.3 7.7 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 eIF3g PF12353.8 PVD35772.1 - 1.8 9.0 31.7 0.97 9.8 1.2 5.2 2 1 3 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G Nipped-B_C PF12830.7 PVD35773.1 - 4.2e-67 225.8 3.7 1.4e-64 217.5 0.1 4.3 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 PVD35773.1 - 9.1e-14 51.5 1.5 3.7e-11 43.1 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 PVD35773.1 - 1.1e-06 28.9 0.1 4.6 7.7 0.0 5.7 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.22 PVD35773.1 - 2.4e-06 27.3 0.4 13 6.3 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 PVD35773.1 - 8.5e-06 25.9 7.0 0.088 12.8 0.0 5.5 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 SHIPPO-rpt PF07004.12 PVD35773.1 - 0.0056 17.5 26.5 6.1 8.0 6.8 7.1 6 1 0 6 6 6 1 Sperm-tail PG-rich repeat V-ATPase_H_C PF11698.8 PVD35773.1 - 0.0095 16.0 4.3 14 5.8 0.0 4.8 4 0 0 4 4 4 1 V-ATPase subunit H Cnd3 PF12719.7 PVD35773.1 - 0.12 11.5 6.2 0.6 9.3 0.0 3.9 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 PVD35773.1 - 0.19 12.3 0.4 67 4.1 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat SCP2 PF02036.17 PVD35774.1 - 3.8e-26 91.5 0.2 7e-26 90.7 0.2 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 PVD35774.1 - 8.4e-23 81.0 0.0 2.4e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PVD35774.1 - 1.9e-11 43.7 0.1 1.6e-09 37.5 0.1 3.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain SpoVAD PF07451.11 PVD35774.1 - 2.5e-05 23.2 0.0 4.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Alkyl_sulf_C PF14864.6 PVD35774.1 - 3.4e-05 24.1 0.0 7.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ACP_syn_III PF08545.10 PVD35774.1 - 3.8e-05 23.4 2.0 0.011 15.5 0.1 3.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 PVD35774.1 - 0.0011 18.6 0.8 0.0093 15.6 0.8 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SCP2_2 PF13530.6 PVD35774.1 - 0.0059 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Sterol carrier protein domain DUF3235 PF11574.8 PVD35774.1 - 0.014 16.2 0.8 4.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DUF2181 PF10223.9 PVD35775.1 - 6.8e-75 251.6 0.5 8.9e-75 251.3 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Xpo1 PF08389.12 PVD35776.1 - 1.5e-23 83.5 15.5 2.5e-22 79.5 2.2 4.6 3 1 1 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 PVD35776.1 - 3.4e-20 71.4 0.5 1.1e-19 69.8 0.5 2.0 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 PVD35776.1 - 1.7e-18 66.4 0.5 8.6e-18 64.2 0.5 2.4 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 PVD35776.1 - 7.9e-08 32.1 2.8 2.8e-07 30.4 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF2397 PF09660.10 PVD35776.1 - 0.12 11.3 0.2 0.69 8.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) OrfA PF17495.2 PVD35776.1 - 0.17 12.1 2.1 17 5.7 0.1 2.8 3 0 0 3 3 3 0 Vpr-like OrfA YjcB PF15940.5 PVD35776.1 - 0.44 10.8 4.8 1.2 9.4 0.2 3.8 3 0 0 3 3 3 0 Family of unknown function PKD_channel PF08016.12 PVD35777.1 - 9.4e-10 37.7 13.3 1.5e-09 37.1 13.3 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PVD35777.1 - 0.00014 21.2 21.8 0.00014 21.2 21.8 2.1 2 1 1 3 3 3 1 Ion transport protein Thioredoxin PF00085.20 PVD35778.1 - 3.3e-30 104.1 0.1 3.6e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PVD35778.1 - 6.3e-08 33.0 0.1 7.4e-07 29.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PVD35778.1 - 5e-07 30.0 0.0 0.0012 19.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 PVD35778.1 - 0.00022 21.3 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 PVD35778.1 - 0.00045 19.7 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 PVD35778.1 - 0.00061 19.7 0.1 0.0053 16.7 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PVD35778.1 - 0.0014 18.4 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 PVD35778.1 - 0.0024 17.7 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 PVD35778.1 - 0.0046 17.2 0.1 0.0073 16.5 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 PVD35778.1 - 0.0066 16.2 0.2 0.04 13.6 0.1 1.9 1 1 1 2 2 2 1 Redoxin HyaE PF07449.11 PVD35778.1 - 0.0091 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 PVD35778.1 - 0.046 14.1 0.0 0.062 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 PVD35778.1 - 0.046 13.8 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain MADF_DNA_bdg PF10545.9 PVD35779.1 - 1.6e-15 57.2 0.4 3.6e-15 56.0 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 PVD35779.1 - 5.2e-05 23.5 0.1 0.00012 22.4 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 PVD35779.1 - 0.002 19.1 0.1 0.0033 18.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SAM_1 PF00536.30 PVD35780.1 - 7.3e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD35780.1 - 1.3e-13 50.8 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD35780.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain XK-related PF09815.9 PVD35781.1 - 8.5e-89 298.0 27.3 1.3e-88 297.4 27.3 1.2 1 0 0 1 1 1 1 XK-related protein RRM_1 PF00076.22 PVD35781.1 - 4.4e-18 64.9 0.0 3.1e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PVD35781.1 - 0.00012 21.9 0.0 0.00037 20.4 0.0 1.8 1 0 0 1 1 1 1 RL domain RRM_3 PF08777.11 PVD35781.1 - 0.011 15.8 0.2 0.45 10.6 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif Calponin PF00402.18 PVD35782.1 - 1.3e-27 95.0 18.8 6.3e-14 51.3 2.9 3.8 4 0 0 4 4 4 3 Calponin family repeat CH PF00307.31 PVD35782.1 - 4.7e-18 65.3 0.0 7.3e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD35782.1 - 8.9e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain dCache_1 PF02743.18 PVD35783.1 - 9.8e-20 71.4 0.0 1.6e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Cache domain VWA_N PF08399.11 PVD35783.1 - 0.0021 18.6 0.1 0.024 15.1 0.1 2.6 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 PVD35783.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain dCache_2 PF08269.11 PVD35783.1 - 0.12 11.5 0.0 0.34 10.0 0.0 1.7 1 0 0 1 1 1 0 Cache domain Fer2 PF00111.27 PVD35784.1 - 1.6e-09 37.6 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GATA PF00320.27 PVD35786.1 - 4.4e-15 55.0 3.1 4.4e-15 55.0 3.1 2.9 2 0 0 2 2 2 1 GATA zinc finger DUF3039 PF11238.8 PVD35786.1 - 0.053 13.3 7.7 0.08 12.7 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Pox_E10 PF04805.12 PVD35786.1 - 1.3 8.9 4.8 20 5.1 0.6 2.6 2 0 0 2 2 2 0 E10-like protein conserved region zf-HYPF PF07503.12 PVD35786.1 - 2.1 8.2 14.7 27 4.7 0.3 4.7 4 0 0 4 4 4 0 HypF finger Pkinase_Tyr PF07714.17 PVD35787.1 - 1.7e-97 325.7 0.0 2.4e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD35787.1 - 2e-44 152.0 0.0 2.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 PVD35787.1 - 1.1e-23 83.3 5.3 1.1e-23 83.3 5.3 2.0 2 0 0 2 2 2 1 Kringle domain I-set PF07679.16 PVD35787.1 - 1.6e-13 50.5 0.0 3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD35787.1 - 1.3e-12 48.1 0.2 1.3e-12 48.1 0.2 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD35787.1 - 2.1e-10 40.8 0.1 6.6e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 PVD35787.1 - 1.4e-09 38.6 2.7 1.4e-09 38.6 2.7 2.0 2 0 0 2 2 2 1 Fz domain ig PF00047.25 PVD35787.1 - 1.3e-07 31.7 0.1 1.3e-07 31.7 0.1 2.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 PVD35787.1 - 2.9e-05 24.2 0.7 0.00079 19.6 0.7 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Haspin_kinase PF12330.8 PVD35787.1 - 0.0076 15.2 0.0 0.0076 15.2 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Mito_fiss_reg PF05308.11 PVD35790.1 - 3.2 7.8 12.9 3.5 7.6 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Chlorophyllase2 PF12740.7 PVD35791.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme F-box-like PF12937.7 PVD35793.1 - 4.8e-07 29.6 1.2 1.1e-06 28.4 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD35793.1 - 5.8e-06 26.0 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD35793.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 F-box DUF4611 PF15387.6 PVD35793.1 - 0.86 9.9 7.0 3 8.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) VEFS-Box PF09733.9 PVD35793.1 - 1 9.1 3.9 3.5 7.4 0.3 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Cation_ATPase_C PF00689.21 PVD35794.1 - 7.4e-44 149.6 3.6 1.5e-43 148.7 0.1 2.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PVD35794.1 - 1.4e-42 145.3 2.1 1.7e-42 145.0 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PVD35794.1 - 3.8e-23 81.4 0.0 7.3e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PVD35794.1 - 2.8e-19 70.2 0.0 7.1e-10 39.5 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PVD35794.1 - 1e-15 57.1 0.0 1.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PVD35794.1 - 7.9e-06 25.8 0.8 0.00062 19.6 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MgtE PF01769.16 PVD35794.1 - 4 7.9 11.0 1.5 9.2 3.4 2.8 3 0 0 3 3 3 0 Divalent cation transporter AIG1 PF04548.16 PVD35796.1 - 1.6e-22 79.9 0.1 2.2e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 AIG1 family Dynamin_N PF00350.23 PVD35796.1 - 0.0036 17.4 0.1 0.0069 16.5 0.1 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 PVD35796.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 PVD35796.1 - 0.0098 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 PVD35796.1 - 0.03 14.9 0.6 0.033 14.7 0.6 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 PVD35796.1 - 0.033 14.3 0.4 0.082 13.0 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.7 PVD35796.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 PVD35796.1 - 0.045 13.9 0.6 0.31 11.1 0.6 2.0 1 1 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 PVD35796.1 - 0.068 13.6 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase IIGP PF05049.13 PVD35796.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.6 PVD35796.1 - 0.08 13.2 0.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 PVD35797.1 - 2.4e-34 118.5 0.0 2.9e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35797.1 - 7.8e-09 35.6 0.0 2.1e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD35797.1 - 0.0034 16.9 0.1 0.0066 16.0 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PVD35797.1 - 0.0055 17.2 1.3 0.0071 16.9 1.3 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD35797.1 - 0.0081 16.1 3.6 0.013 15.4 1.1 2.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PVD35797.1 - 0.0085 16.2 2.2 0.14 12.3 0.9 2.2 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 PVD35797.1 - 0.018 14.5 0.2 0.038 13.4 0.1 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 PVD35797.1 - 0.047 14.2 0.1 0.5 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PVD35797.1 - 0.052 13.3 0.2 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SET_assoc PF11767.8 PVD35797.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated T2SSE PF00437.20 PVD35797.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.16 PVD35798.1 - 8.7e-56 188.6 0.9 7.5e-38 130.0 0.0 2.9 2 1 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD35798.1 - 8e-13 48.5 0.1 2.9e-08 33.8 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35798.1 - 1.1e-08 35.4 0.1 0.18 11.9 0.0 3.6 2 1 1 3 3 3 3 Dynamin family ABC_tran PF00005.27 PVD35798.1 - 4.7e-07 30.4 0.0 0.031 14.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 PVD35798.1 - 1.4e-06 28.3 1.7 0.0045 16.9 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PVD35798.1 - 0.0001 22.0 0.4 0.22 11.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Roc PF08477.13 PVD35798.1 - 0.00059 20.1 0.3 0.6 10.3 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PVD35798.1 - 0.0012 19.2 0.2 0.86 9.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 PVD35798.1 - 0.0018 18.4 2.4 1.6 8.7 0.1 3.0 2 1 1 3 3 3 2 Helicase HerA, central domain Guanylate_kin PF00625.21 PVD35798.1 - 0.0019 17.9 0.1 1.2 8.8 0.0 2.6 3 0 0 3 3 3 2 Guanylate kinase AAA_7 PF12775.7 PVD35798.1 - 0.0086 15.6 0.4 0.28 10.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 PVD35798.1 - 0.014 14.7 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Septin Brr6_like_C_C PF10104.9 PVD35798.1 - 0.017 14.9 0.2 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain TniB PF05621.11 PVD35798.1 - 0.021 14.2 0.2 2.7 7.4 0.0 2.6 2 1 1 3 3 3 0 Bacterial TniB protein Lipase_GDSL_2 PF13472.6 PVD35798.1 - 0.025 15.0 0.0 0.08 13.3 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family FtsK_SpoIIIE PF01580.18 PVD35798.1 - 0.026 13.9 0.2 4.9 6.4 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 PVD35798.1 - 0.033 13.5 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IIGP PF05049.13 PVD35798.1 - 0.054 12.5 0.2 3.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.22 PVD35798.1 - 0.06 13.7 0.2 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Ras PF00071.22 PVD35798.1 - 0.061 12.9 0.1 11 5.6 0.0 3.1 4 0 0 4 4 4 0 Ras family Sigma54_activat PF00158.26 PVD35798.1 - 0.062 13.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 PVD35798.1 - 0.07 13.0 0.4 6.4 6.7 0.0 2.8 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 PVD35798.1 - 0.1 12.3 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 PVD35798.1 - 0.11 12.9 2.0 5.9 7.2 0.1 3.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 PVD35798.1 - 0.14 12.2 0.1 16 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 PVD35798.1 - 0.23 10.3 3.4 6 5.7 0.0 3.1 4 0 0 4 4 4 0 AAA-like domain AAA_23 PF13476.6 PVD35798.1 - 0.24 11.9 2.9 7.7 7.0 0.2 2.9 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 PVD35799.1 - 3.9e-41 140.7 0.0 6.1e-41 140.1 0.0 1.3 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35799.1 - 4.2e-10 39.7 0.1 4.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PVD35799.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 PVD35799.1 - 0.0073 16.4 7.0 1.2 9.2 1.7 3.0 2 1 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD35799.1 - 0.017 15.1 1.9 0.024 14.5 0.7 1.9 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 PVD35799.1 - 0.023 15.2 0.1 0.048 14.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Glyco_hydro_3_C PF01915.22 PVD35799.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain FeoB_N PF02421.18 PVD35799.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 PVD35799.1 - 0.079 13.2 0.4 0.47 10.7 0.4 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PVD35800.1 - 1.5e-30 106.1 0.1 1.8e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PVD35800.1 - 3.8e-08 33.4 0.1 4.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD35800.1 - 0.00098 19.1 0.7 0.0015 18.4 0.5 1.5 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PVD35800.1 - 0.06 13.9 0.5 0.12 12.9 0.6 1.3 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 PVD35800.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PVD35800.1 - 0.12 12.4 1.6 0.23 11.5 1.5 1.5 1 1 1 2 2 2 0 Dynamin family DUF2075 PF09848.9 PVD35800.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.16 PVD35801.1 - 8.2e-72 241.0 1.7 7.4e-36 123.5 0.2 2.0 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD35801.1 - 6.5e-22 77.8 0.1 5e-10 39.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD35801.1 - 2.1e-13 50.7 0.0 6.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Dynamin family ABC_tran PF00005.27 PVD35801.1 - 9.7e-12 45.6 0.7 0.00016 22.2 0.1 2.8 2 2 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 PVD35801.1 - 7.2e-10 39.0 2.2 0.00072 19.5 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PVD35801.1 - 2.6e-07 30.2 0.3 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 PVD35801.1 - 3.9e-06 26.5 0.6 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Sigma54_activat PF00158.26 PVD35801.1 - 8.7e-06 25.5 0.7 0.08 12.6 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Guanylate_kin PF00625.21 PVD35801.1 - 1.2e-05 25.1 4.0 0.061 13.0 0.0 3.1 4 0 0 4 4 2 2 Guanylate kinase AAA_15 PF13175.6 PVD35801.1 - 1.3e-05 25.1 4.6 0.019 14.7 0.5 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 PVD35801.1 - 1.5e-05 24.6 2.3 0.09 12.3 0.2 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD35801.1 - 1.7e-05 24.6 0.2 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 PVD35801.1 - 1.9e-05 25.2 1.5 0.19 12.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain DUF815 PF05673.13 PVD35801.1 - 1.9e-05 24.0 7.0 1.1 8.4 0.2 4.6 5 1 0 5 5 4 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 PVD35801.1 - 2.5e-05 24.6 0.1 0.37 11.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 PVD35801.1 - 4.4e-05 23.7 0.7 0.42 10.8 0.1 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 PVD35801.1 - 5e-05 22.8 0.1 0.078 12.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA PF00004.29 PVD35801.1 - 5.2e-05 23.7 0.3 0.78 10.2 0.0 3.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Ycf9 PF01737.17 PVD35801.1 - 0.0001 22.1 0.2 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 YCF9 TrwB_AAD_bind PF10412.9 PVD35801.1 - 0.00011 21.3 0.4 0.38 9.6 0.1 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.19 PVD35801.1 - 0.00013 21.5 3.0 0.2 11.1 0.0 3.3 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain IIGP PF05049.13 PVD35801.1 - 0.00014 21.0 2.7 0.21 10.6 0.1 3.0 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 PVD35801.1 - 0.00015 21.0 2.5 0.62 9.1 0.0 3.6 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_24 PF13479.6 PVD35801.1 - 0.00022 21.0 0.2 0.42 10.3 0.1 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 PVD35801.1 - 0.00024 21.2 0.3 2.2 8.4 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain FeoB_N PF02421.18 PVD35801.1 - 0.00024 20.7 0.1 0.71 9.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_10 PF12846.7 PVD35801.1 - 0.00056 18.9 2.9 0.31 9.9 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain DUF1796 PF08795.10 PVD35801.1 - 0.00056 19.9 3.5 1.3 8.9 0.1 3.9 2 2 2 4 4 4 1 Putative papain-like cysteine peptidase (DUF1796) AAA_16 PF13191.6 PVD35801.1 - 0.00084 19.8 0.0 0.8 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 PVD35801.1 - 0.00091 18.7 0.1 1.6 8.1 0.1 2.6 2 0 0 2 2 2 2 Bacterial TniB protein CobU PF02283.16 PVD35801.1 - 0.00092 18.8 0.6 6.7 6.2 0.0 4.1 4 0 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF87 PF01935.17 PVD35801.1 - 0.0011 19.1 2.9 1.1 9.2 0.1 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain RNA_helicase PF00910.22 PVD35801.1 - 0.0012 19.2 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 PVD35801.1 - 0.0013 18.1 0.0 0.46 9.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 PVD35801.1 - 0.0017 18.1 0.8 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 PVD35801.1 - 0.0027 17.2 5.2 0.24 10.8 0.0 3.5 4 0 0 4 4 4 1 ADP-ribosylation factor family ATP-synt_ab PF00006.25 PVD35801.1 - 0.0048 16.6 0.3 2 8.0 0.1 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Hpr_kinase_C PF07475.12 PVD35801.1 - 0.0077 15.8 0.3 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Cob_adeno_trans PF01923.18 PVD35801.1 - 0.012 15.8 0.1 22 5.1 0.0 3.7 4 0 0 4 4 4 0 Cobalamin adenosyltransferase AAA_28 PF13521.6 PVD35801.1 - 0.012 15.9 0.6 2.8 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 PVD35801.1 - 0.016 14.5 8.0 0.82 8.9 0.0 3.4 4 0 0 4 4 4 0 Septin FANCI_HD1 PF14679.6 PVD35801.1 - 0.018 15.0 0.1 10 6.1 0.0 3.3 3 0 0 3 3 2 0 FANCI helical domain 1 GTP_EFTU PF00009.27 PVD35801.1 - 0.019 14.5 2.0 4.7 6.7 0.2 3.4 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 PVD35801.1 - 0.028 13.6 4.4 0.9 8.6 0.9 2.5 2 1 0 2 2 2 0 G-protein alpha subunit ResIII PF04851.15 PVD35801.1 - 0.032 14.2 0.0 13 5.8 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Cauli_AT PF03233.13 PVD35801.1 - 0.032 14.2 6.5 0.49 10.3 1.0 2.5 2 0 0 2 2 2 0 Aphid transmission protein Gtr1_RagA PF04670.12 PVD35801.1 - 0.035 13.5 1.0 7.7 5.8 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region DUF1289 PF06945.13 PVD35801.1 - 0.04 13.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) GSHPx PF00255.19 PVD35801.1 - 0.045 13.3 1.3 13 5.4 0.0 3.7 2 2 2 4 4 4 0 Glutathione peroxidase Peptidase_M55 PF04951.13 PVD35801.1 - 0.051 13.0 0.0 16 4.8 0.0 3.1 3 0 0 3 3 3 0 D-aminopeptidase EspG PF06872.11 PVD35801.1 - 0.055 12.0 0.1 5.4 5.5 0.0 2.3 2 0 0 2 2 2 0 EspG protein AAA_33 PF13671.6 PVD35801.1 - 0.061 13.5 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 PVD35801.1 - 0.066 12.8 2.1 17 5.0 0.0 3.5 4 1 0 4 4 4 0 Ras family NaeI PF09126.10 PVD35801.1 - 0.078 12.2 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease NaeI AAA_5 PF07728.14 PVD35801.1 - 0.088 12.8 0.2 21 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TonB_2 PF13103.6 PVD35801.1 - 0.11 12.7 4.1 2 8.7 0.3 3.5 4 0 0 4 4 3 0 TonB C terminal Mon1 PF03164.14 PVD35801.1 - 0.29 10.2 1.4 11 5.0 0.1 2.1 2 0 0 2 2 2 0 Trafficking protein Mon1 rhaM PF05336.13 PVD35801.1 - 0.33 11.0 2.5 24 5.0 0.2 3.0 3 0 0 3 3 2 0 L-rhamnose mutarotase PRIMA1 PF16101.5 PVD35801.1 - 0.41 10.7 5.9 3.7 7.6 1.7 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Zeta_toxin PF06414.12 PVD35801.1 - 0.94 8.7 2.7 18 4.5 0.1 2.7 3 0 0 3 3 2 0 Zeta toxin NACHT PF05729.12 PVD35801.1 - 1.1 9.2 10.7 42 4.0 0.2 5.1 4 2 2 6 6 6 0 NACHT domain MCM PF00493.23 PVD35801.1 - 1.1 8.3 5.2 4 6.5 0.1 3.8 4 1 1 5 5 5 0 MCM P-loop domain NUFIP1 PF10453.9 PVD35801.1 - 9.6 6.1 8.2 36 4.3 0.2 3.4 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) AIG1 PF04548.16 PVD35802.1 - 1.6e-27 96.3 0.1 6.1e-15 55.1 0.1 2.1 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PVD35802.1 - 0.00026 21.1 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.13 PVD35802.1 - 0.015 14.5 0.1 0.058 12.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 PVD35802.1 - 0.064 13.2 0.4 0.5 10.3 0.4 2.1 1 1 0 1 1 1 0 RsgA GTPase Ras PF00071.22 PVD35802.1 - 0.12 11.9 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ras family SLT PF01464.20 PVD35803.1 - 0.0047 16.6 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 2 Transglycosylase SLT domain Stress-antifung PF01657.17 PVD35804.1 - 0.5 11.0 3.4 3.4 8.4 3.4 2.0 1 1 0 1 1 1 0 Salt stress response/antifungal SH3_3 PF08239.11 PVD35805.1 - 3.5e-09 36.8 0.3 6.2e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SLT PF01464.20 PVD35805.1 - 0.0063 16.2 0.1 0.03 14.0 0.1 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain SH3_4 PF06347.13 PVD35805.1 - 0.054 13.3 1.9 0.3 10.9 1.9 2.2 1 1 0 1 1 1 0 Bacterial SH3 domain NOA36 PF06524.12 PVD35808.1 - 0.0072 15.7 5.6 0.008 15.5 5.6 1.1 1 0 0 1 1 1 1 NOA36 protein FAM176 PF14851.6 PVD35808.1 - 0.11 12.1 2.2 0.15 11.8 2.2 1.2 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 PVD35808.1 - 0.25 10.2 4.5 0.28 10.1 4.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Dicty_REP PF05086.12 PVD35808.1 - 0.89 7.5 3.3 0.91 7.4 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.13 PVD35808.1 - 1.7 6.6 7.9 1.9 6.5 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4632 PF15451.6 PVD35808.1 - 1.8 8.7 4.6 2.7 8.1 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF773 PF05600.12 PVD35809.1 - 3e-150 501.3 6.4 3.3e-150 501.2 6.4 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Sigma70_ner PF04546.13 PVD35809.1 - 0.023 14.6 1.3 0.048 13.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-70, non-essential region MSG PF02349.15 PVD35809.1 - 0.069 13.4 0.1 0.23 11.7 0.1 2.0 1 0 0 1 1 1 0 Major surface glycoprotein Baculo_PEP_C PF04513.12 PVD35809.1 - 0.11 12.5 0.6 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus H-kinase_dim PF02895.14 PVD35809.1 - 3 8.3 7.3 5.3 7.5 0.1 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Beta-lactamase PF00144.24 PVD35810.1 - 6.8e-36 124.2 0.0 1.5e-35 123.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 PVD35810.1 - 2.5e-05 24.7 0.0 5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) MDMPI_N PF11716.8 PVD35810.1 - 0.091 13.4 1.4 4.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain zf-H2C2_2 PF13465.6 PVD35811.1 - 2.5e-33 113.0 57.6 8.1e-07 29.2 0.4 10.0 9 1 1 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 PVD35811.1 - 2.1e-23 81.4 57.0 5.3e-05 23.4 0.7 9.8 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD35811.1 - 8.3e-22 76.0 61.5 0.0027 18.4 0.4 10.0 10 0 0 10 10 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD35811.1 - 5.2e-14 52.1 16.4 0.051 13.9 0.4 8.1 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD35811.1 - 3.2e-10 40.0 30.2 0.081 13.3 0.5 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 PVD35811.1 - 0.00028 21.3 0.4 0.00028 21.3 0.4 5.2 6 0 0 6 6 5 2 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 PVD35811.1 - 0.0003 21.2 36.4 0.033 14.6 0.4 8.8 3 1 5 8 8 8 2 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 PVD35811.1 - 0.0025 18.1 36.6 0.1 12.9 8.3 5.4 4 1 0 5 5 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PVD35811.1 - 0.013 15.2 0.4 0.013 15.2 0.4 7.7 10 0 0 10 10 9 0 zinc-finger C2H2-type HypA PF01155.19 PVD35811.1 - 0.023 14.7 18.1 0.55 10.3 0.5 5.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHCC PF10276.9 PVD35811.1 - 0.035 14.2 1.1 19 5.4 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger domain NeuB PF03102.14 PVD35811.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NeuB family zf-C2HC_2 PF13913.6 PVD35811.1 - 0.16 11.9 17.1 0.25 11.3 0.1 5.6 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 PVD35811.1 - 0.2 11.8 0.1 0.2 11.8 0.1 7.2 6 1 1 7 7 7 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 PVD35811.1 - 0.48 10.3 5.8 6.8 6.6 0.3 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif BolA PF01722.18 PVD35811.1 - 1.5 9.1 7.7 0.23 11.7 0.2 3.2 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_6 PF13912.6 PVD35811.1 - 2.2 8.4 48.5 0.16 12.0 0.5 8.5 9 0 0 9 9 9 0 C2H2-type zinc finger zf-CHY PF05495.12 PVD35811.1 - 3.4 8.2 31.6 2.1 8.9 3.3 5.6 4 1 1 5 5 5 0 CHY zinc finger Zf_RING PF16744.5 PVD35811.1 - 3.5 7.8 10.9 12 6.0 0.1 4.3 3 1 1 4 4 4 0 KIAA1045 RING finger TIR_2 PF13676.6 PVD35812.1 - 7.1e-10 39.5 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 TIR domain Death PF00531.22 PVD35812.1 - 1.5e-06 28.3 0.0 9.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Death domain TIR PF01582.20 PVD35812.1 - 6.2e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain PEHE PF15275.6 PVD35813.1 - 1.6e-09 38.4 0.2 1.6e-09 38.4 0.2 5.7 6 1 0 6 6 6 1 PEHE domain Cation_ATPase_N PF00690.26 PVD35813.1 - 0.12 12.1 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DCX PF03607.17 PVD35814.1 - 2.8e-33 113.8 0.0 2.5e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Pro-kuma_activ PF09286.11 PVD35814.1 - 0.0076 16.6 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Pkinase PF00069.25 PVD35815.1 - 2.7e-55 187.6 0.0 4.9e-30 104.8 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PVD35815.1 - 1.2e-20 73.9 0.0 2.4e-12 46.7 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD35815.1 - 0.12 11.7 1.5 0.37 10.1 0.0 2.4 3 0 0 3 3 3 0 Kinase-like Presenilin PF01080.17 PVD35815.1 - 0.4 9.4 5.8 0.4 9.4 5.8 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 PVD35815.1 - 0.78 8.0 17.6 1 7.6 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein VWC PF00093.18 PVD35816.1 - 6.2e-14 52.1 37.3 3.4e-08 33.7 15.7 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain TILa PF12714.7 PVD35816.1 - 0.023 14.6 7.1 0.023 14.6 7.1 2.9 2 2 0 2 2 2 0 TILa domain Metallothio_6 PF05522.11 PVD35816.1 - 6.5 7.3 32.3 6.8 7.3 12.5 2.7 2 0 0 2 2 2 0 Metallothionein FYVE PF01363.21 PVD35817.1 - 9.5e-05 22.5 1.7 0.15 12.2 7.0 2.0 1 1 1 2 2 2 2 FYVE zinc finger zf-CCHC_2 PF13696.6 PVD35817.1 - 0.021 14.6 0.4 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-B_box PF00643.24 PVD35817.1 - 0.11 12.6 6.8 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-AN1 PF01428.16 PVD35817.1 - 0.16 12.2 5.8 0.35 11.1 0.7 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger DUF2062 PF09835.9 PVD35818.1 - 0.057 13.3 0.3 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4448 PF14610.6 PVD35818.1 - 0.089 12.6 0.3 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EB PF01683.18 PVD35818.1 - 4.2 7.7 11.4 0.19 12.0 4.8 2.3 2 0 0 2 2 2 0 EB module TIR_2 PF13676.6 PVD35819.1 - 4e-21 75.8 0.0 1.1e-20 74.4 0.0 1.8 1 0 0 1 1 1 1 TIR domain SAM_3 PF18016.1 PVD35819.1 - 0.0022 17.8 0.0 0.0082 15.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD35819.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Arm PF00514.23 PVD35819.1 - 0.091 12.8 0.2 7.3 6.8 0.0 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SAM_2 PF07647.17 PVD35819.1 - 0.091 12.9 0.0 8.6 6.6 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TIR PF01582.20 PVD35819.1 - 0.095 12.5 0.4 2.7 7.8 0.1 2.8 2 1 1 3 3 3 0 TIR domain Peptidase_M2 PF01401.18 PVD35821.1 - 1.5e-10 40.3 0.3 2.6e-09 36.2 0.3 2.6 1 1 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M2 PF01401.18 PVD35822.1 - 0 2605.0 11.5 3.1e-246 818.4 0.1 5.0 4 1 1 5 5 5 5 Angiotensin-converting enzyme Organ_specific PF10950.8 PVD35822.1 - 0.019 15.7 0.1 32 5.2 0.0 3.9 4 0 0 4 4 4 0 Organ specific protein Cut12 PF11500.8 PVD35822.1 - 0.044 13.7 2.1 3.2 7.7 0.1 3.4 3 0 0 3 3 3 0 Spindle pole body formation-associated protein Glyco_hydro_2_N PF02837.18 PVD35823.1 - 6.6e-07 29.4 0.2 1.5e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 PVD35823.1 - 0.0038 16.4 0.0 0.02 14.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain RL11D PF11088.8 PVD35823.1 - 0.094 13.0 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Ig_mannosidase PF17753.1 PVD35824.1 - 5.2e-18 64.6 0.1 1.6e-17 63.0 0.1 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 PVD35824.1 - 3.9e-07 30.1 8.2 1e-06 28.8 0.2 3.8 4 0 0 4 4 4 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 PVD35824.1 - 0.03 14.9 2.7 0.049 14.2 0.1 2.7 3 1 0 3 3 3 0 Mannosidase Ig/CBM-like domain DUF3583 PF12126.8 PVD35825.1 - 0.01 15.3 0.5 0.011 15.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) KH_1 PF00013.29 PVD35826.1 - 4.7e-52 173.7 16.6 2.1e-18 65.9 1.0 3.5 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 PVD35826.1 - 8.1e-13 48.0 6.9 0.0015 18.4 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PVD35826.1 - 4.9e-07 29.5 1.6 0.29 11.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 PVD35826.1 - 1.9e-05 24.6 7.8 0.35 11.0 0.6 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 PVD35826.1 - 0.0083 16.1 0.0 0.27 11.2 0.0 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain RIFIN PF02009.16 PVD35830.1 - 0.12 12.3 11.8 0.17 11.8 11.8 1.2 1 0 0 1 1 1 0 Rifin LAP1C PF05609.12 PVD35830.1 - 0.82 8.7 21.0 0.99 8.4 21.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4196 PF13846.6 PVD35830.1 - 2.2 8.5 26.1 35 4.6 9.2 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) BamHI PF02923.15 PVD35830.1 - 2.6 7.7 6.8 15 5.3 0.5 2.4 1 1 1 2 2 2 0 Restriction endonuclease BamHI DUF724 PF05266.14 PVD35830.1 - 2.7 7.8 14.3 36 4.1 13.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) RR_TM4-6 PF06459.12 PVD35830.1 - 3.2 7.5 17.9 4.7 6.9 17.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 PVD35830.1 - 4.2 6.2 10.5 5.4 5.8 10.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cornichon PF03311.14 PVD35830.1 - 7.7 6.9 9.5 21 5.5 0.7 3.9 2 2 2 4 4 4 0 Cornichon protein Bap31_Bap29_C PF18035.1 PVD35830.1 - 8.4 6.5 17.9 1.8e+04 -8.3 17.9 4.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain IlvGEDA_leader PF08046.11 PVD35831.1 - 0.11 12.0 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide MOSC_N PF03476.16 PVD35835.1 - 2.5e-26 91.9 0.1 2.8e-25 88.5 0.0 2.5 3 0 0 3 3 3 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 PVD35835.1 - 1e-16 60.9 0.0 2.2e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V MOSC PF03473.17 PVD35835.1 - 5.9e-11 42.5 0.4 2.4e-09 37.3 0.1 2.5 1 1 1 2 2 2 1 MOSC domain FAM101 PF15068.6 PVD35836.1 - 0.023 14.7 0.2 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 FAM101 family GAF PF01590.26 PVD35836.1 - 0.035 14.7 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 GAF domain MOSC_N PF03476.16 PVD35837.1 - 6.7e-11 42.1 0.0 7.3e-07 29.1 0.0 2.6 2 1 1 3 3 3 2 MOSC N-terminal beta barrel domain Hormone_3 PF00159.18 PVD35838.1 - 2.3e-11 43.5 3.3 3.6e-11 42.9 3.3 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide PX PF00787.24 PVD35839.1 - 4.4e-20 71.7 0.5 6.8e-20 71.1 0.5 1.2 1 0 0 1 1 1 1 PX domain Acyl-ACP_TE PF01643.17 PVD35840.1 - 6.1e-06 25.7 0.0 9.8e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 PVD35840.1 - 0.097 13.2 0.0 4.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Thioesterase-like superfamily PNP_UDP_1 PF01048.20 PVD35841.1 - 0.08 12.2 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Phosphorylase superfamily Phage_tail_3 PF08813.11 PVD35841.1 - 0.16 11.5 1.3 2.6 7.6 0.0 2.3 1 1 1 2 2 2 0 Phage tail tube protein, TTP WSC PF01822.19 PVD35842.1 - 0.016 15.3 0.2 0.027 14.7 0.2 1.4 1 1 0 1 1 1 0 WSC domain OppC_N PF12911.7 PVD35843.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C WSC PF01822.19 PVD35843.1 - 0.01 16.0 1.6 0.02 15.1 0.0 1.9 2 0 0 2 2 2 0 WSC domain TMIE PF16038.5 PVD35843.1 - 0.28 11.1 1.1 0.42 10.5 1.1 1.2 1 0 0 1 1 1 0 TMIE protein Homeodomain PF00046.29 PVD35845.1 - 3.2e-21 74.9 2.0 5.7e-21 74.1 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Exo_endo_phos PF03372.23 PVD35846.1 - 4e-05 23.3 0.0 0.00064 19.3 0.0 2.0 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Homeodomain PF00046.29 PVD35847.1 - 1.7e-21 75.8 2.9 2.7e-21 75.2 2.9 1.3 1 0 0 1 1 1 1 Homeodomain DUF1087 PF06465.13 PVD35848.1 - 0.098 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) GAF PF01590.26 PVD35849.1 - 2.1e-30 106.1 0.0 6.3e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PVD35849.1 - 1.5e-14 54.5 0.0 1.6e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain PDEase_I PF00233.19 PVD35849.1 - 6e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.6 PVD35849.1 - 2.2e-05 24.8 0.0 0.01 16.2 0.0 3.6 2 2 0 2 2 2 1 GAF domain LRR_8 PF13855.6 PVD35850.1 - 1.3e-07 31.3 21.0 8e-05 22.3 3.1 4.6 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 PVD35850.1 - 2.5e-05 23.9 4.4 7.6e-05 22.3 1.1 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 PVD35850.1 - 7.3e-05 23.1 22.1 0.00043 20.6 1.7 5.2 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) LIP1 PF15904.5 PVD35850.1 - 0.00011 22.4 0.1 0.00089 19.6 0.1 2.6 2 1 0 2 2 2 1 LKB1 serine/threonine kinase interacting protein 1 Adeno_VII PF03228.14 PVD35850.1 - 0.00049 20.7 0.5 0.0014 19.3 0.5 1.7 1 0 0 1 1 1 1 Adenoviral core protein VII LRR_6 PF13516.6 PVD35850.1 - 0.51 10.5 16.7 13 6.1 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat NAD_Gly3P_dh_N PF01210.23 PVD35851.1 - 5e-55 185.8 0.6 1e-54 184.8 0.3 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PVD35851.1 - 4.5e-47 159.9 0.1 9.1e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 PVD35851.1 - 0.0052 17.3 0.1 0.75 10.4 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 PVD35851.1 - 0.012 15.2 0.2 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 PVD35851.1 - 0.037 13.7 0.1 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FMN_red PF03358.15 PVD35851.1 - 0.092 12.5 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 NADPH-dependent FMN reductase NAD_binding_2 PF03446.15 PVD35852.1 - 1.6e-46 158.4 0.9 2.4e-46 157.8 0.9 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PVD35852.1 - 1.1e-33 116.1 0.1 3.3e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 PVD35852.1 - 5.7e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PVD35852.1 - 3e-06 27.7 0.0 7.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 PVD35852.1 - 0.00023 21.1 0.6 0.0017 18.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 PVD35852.1 - 0.0017 18.0 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 PVD35852.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 PVD35852.1 - 0.055 13.1 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 PVD35852.1 - 0.056 13.0 0.1 0.95 9.0 0.0 2.2 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_deac_2 PF04748.13 PVD35852.1 - 0.089 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase RRM_1 PF00076.22 PVD35853.1 - 4.5e-12 45.6 0.0 9e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC4_C PF14629.6 PVD35854.1 - 1e-50 172.1 2.3 1.4e-50 171.7 2.3 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 PVD35854.1 - 4.9e-05 23.8 0.1 8.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD35854.1 - 0.0019 18.6 0.7 0.005 17.2 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 PVD35854.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain YqaJ PF09588.10 PVD35855.1 - 6.9e-10 39.3 0.0 2.7e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain Fer4_24 PF18109.1 PVD35855.1 - 0.08 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain Bax1-I PF01027.20 PVD35856.1 - 2.7e-32 112.3 33.5 3.2e-32 112.1 33.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Hum_adeno_E3A PF05393.11 PVD35856.1 - 3.2 7.8 7.6 1.4 8.9 4.5 2.0 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein ACBP PF00887.19 PVD35857.1 - 4.1e-22 78.2 0.0 7.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_60s PF00428.19 PVD35857.1 - 0.55 10.9 5.1 1.3 9.7 5.0 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein 7tm_1 PF00001.21 PVD35858.1 - 1.2e-41 142.8 12.9 1.8e-41 142.3 12.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD35858.1 - 9.8e-06 25.5 8.5 9.8e-06 25.5 8.5 2.3 2 1 0 2 2 2 1 Olfactory receptor Thioredoxin PF00085.20 PVD35860.1 - 3.9e-130 425.1 11.4 2e-28 98.4 0.2 6.1 6 0 0 6 6 6 6 Thioredoxin Thioredoxin_2 PF13098.6 PVD35860.1 - 7.3e-32 110.1 19.9 1.8e-07 31.5 0.1 8.0 6 4 0 6 6 6 4 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PVD35860.1 - 2.4e-25 88.5 0.5 0.00023 21.3 0.0 5.7 5 0 0 5 5 5 5 Thioredoxin-like AhpC-TSA PF00578.21 PVD35860.1 - 1.6e-24 86.2 9.9 0.00013 21.9 0.0 6.6 7 0 0 7 7 7 5 AhpC/TSA family Thioredoxin_8 PF13905.6 PVD35860.1 - 2.1e-19 69.6 7.8 0.048 14.0 0.0 8.6 6 3 2 8 8 8 5 Thioredoxin-like OST3_OST6 PF04756.13 PVD35860.1 - 8.4e-19 68.0 3.5 7e-06 25.6 0.0 5.4 4 2 2 6 6 6 4 OST3 / OST6 family, transporter family TraF PF13728.6 PVD35860.1 - 1.4e-11 44.7 7.4 0.022 14.6 0.0 6.2 5 2 1 6 6 6 4 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 PVD35860.1 - 7.1e-11 42.3 8.5 0.0066 16.4 0.4 6.1 4 2 0 5 5 5 2 Thioredoxin-like domain Redoxin PF08534.10 PVD35860.1 - 1e-10 41.5 11.9 0.12 12.1 0.0 6.5 8 0 0 8 8 8 4 Redoxin Thioredoxin_9 PF14595.6 PVD35860.1 - 3e-07 30.3 0.2 2.7 7.8 0.0 4.8 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_3 PF13192.6 PVD35860.1 - 1.4e-06 28.2 5.2 0.93 9.6 0.0 5.3 6 0 0 6 6 6 3 Thioredoxin domain Glutaredoxin PF00462.24 PVD35860.1 - 1.8e-05 24.8 13.9 1.3 9.3 0.0 5.3 5 0 0 5 5 5 4 Glutaredoxin HyaE PF07449.11 PVD35860.1 - 5.4e-05 23.1 0.0 2 8.4 0.0 4.7 4 1 0 4 4 4 1 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 PVD35860.1 - 0.0018 17.9 0.4 19 4.9 0.0 4.8 5 1 0 5 5 5 0 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.14 PVD35860.1 - 0.018 15.4 0.0 3.2 8.2 0.0 3.8 4 0 0 4 4 4 0 Glutaredoxin-like domain (DUF836) Methyltrans_RNA PF04452.14 PVD35860.1 - 0.097 12.0 0.2 0.49 9.7 0.1 1.9 2 0 0 2 2 2 0 RNA methyltransferase RVT_1 PF00078.27 PVD35861.1 - 1.8e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2703 PF10865.8 PVD35861.1 - 0.041 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) Ig_3 PF13927.6 PVD35862.1 - 8.5e-72 237.8 4.0 9.7e-12 45.3 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD35862.1 - 8.1e-63 208.5 0.0 7.3e-12 45.2 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD35862.1 - 5.5e-52 174.0 6.1 1.4e-09 38.1 0.1 6.4 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 PVD35862.1 - 4.8e-45 151.6 6.9 9.8e-10 38.5 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 PVD35862.1 - 7.9e-20 71.0 12.4 1e-07 32.2 0.1 4.8 4 0 0 4 4 4 3 Fibronectin type III domain V-set PF07686.17 PVD35862.1 - 1.2e-18 67.2 15.7 0.0043 17.2 0.1 10.6 7 4 2 9 9 9 5 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD35862.1 - 1.1e-07 31.3 0.4 0.14 11.8 0.0 5.6 6 0 0 6 6 6 2 Immunoglobulin domain Ig_5 PF16681.5 PVD35862.1 - 3.6e-07 30.5 0.0 0.12 12.7 0.0 5.9 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD35862.1 - 1.2e-06 28.5 0.0 0.74 9.9 0.0 6.0 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD35862.1 - 2.4e-06 27.5 0.4 0.32 11.1 0.0 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 PVD35862.1 - 0.00026 21.1 0.7 11 6.3 0.0 4.9 4 1 1 5 5 5 1 Immunoglobulin C2-set domain Pur_ac_phosph_N PF16656.5 PVD35862.1 - 0.00026 21.5 5.2 0.00078 20.0 0.0 3.9 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 PVD35862.1 - 0.0031 17.5 0.1 5.9 7.0 0.0 4.4 5 0 0 5 5 5 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 PVD35862.1 - 0.03 14.5 0.0 3.1 8.0 0.0 3.6 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 Methyltransf_31 PF13847.6 PVD35864.1 - 2.5e-24 85.8 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD35864.1 - 5.9e-22 78.2 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD35864.1 - 7.1e-22 77.9 0.0 1.3e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD35864.1 - 1.3e-20 73.7 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PVD35864.1 - 2.4e-14 53.9 0.0 1.7e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD35864.1 - 1.5e-13 50.9 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD35864.1 - 2.8e-09 37.0 0.0 4.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PVD35864.1 - 7.4e-07 28.8 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD35864.1 - 2.2e-05 24.1 0.0 5.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 PVD35864.1 - 4.3e-05 23.5 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD35864.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase GCD14 PF08704.10 PVD35864.1 - 0.0052 16.5 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 PVD35864.1 - 0.0053 16.1 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 PVD35864.1 - 0.0077 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 PVD35864.1 - 0.01 16.0 0.0 0.052 13.6 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 PVD35864.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 PVD35864.1 - 0.017 15.0 0.0 0.087 12.7 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 PVD35864.1 - 0.02 14.5 0.2 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 PVD35864.1 - 0.11 12.8 0.3 0.41 11.0 0.1 1.9 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 PVD35865.1 - 7.1e-23 81.1 0.0 1.4e-22 80.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD35865.1 - 5.1e-21 75.2 0.0 9.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD35865.1 - 1.5e-20 73.6 0.0 3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD35865.1 - 2.7e-20 72.7 0.0 4.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PVD35865.1 - 5.2e-15 55.7 0.0 8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD35865.1 - 1.5e-13 51.3 0.0 4.8e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 PVD35865.1 - 5.7e-09 36.0 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PVD35865.1 - 1.3e-05 24.8 0.0 3.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 PVD35865.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PVD35865.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 PVD35865.1 - 0.00055 19.3 0.0 0.00094 18.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 PVD35865.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_9 PF08003.11 PVD35865.1 - 0.0083 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 PVD35865.1 - 0.021 14.7 0.2 0.17 11.7 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 PVD35865.1 - 0.037 13.6 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 PVD35865.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 PVD35865.1 - 0.13 12.6 0.1 0.49 10.7 0.1 1.8 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Fibrillarin PF01269.17 PVD35865.1 - 0.17 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin zf-C2H2 PF00096.26 PVD35866.1 - 2.7e-48 159.8 124.6 3.3e-06 27.2 0.7 16.4 16 0 0 16 16 16 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD35866.1 - 6.9e-47 154.0 117.0 0.00033 21.3 0.8 16.4 16 0 0 16 16 16 15 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD35866.1 - 6.8e-34 114.8 133.7 1e-08 35.2 0.1 16.1 18 0 0 18 18 15 10 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD35866.1 - 1.6e-17 63.3 78.5 0.0045 17.2 0.2 15.0 16 0 0 16 16 15 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD35866.1 - 3.1e-10 39.8 111.5 0.0052 16.8 0.1 16.3 16 1 0 16 16 16 7 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PVD35866.1 - 5.1e-05 24.0 2.6 5.1e-05 24.0 2.6 10.3 2 2 3 7 7 7 1 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 PVD35866.1 - 0.00017 21.4 2.1 0.00017 21.4 2.1 10.0 12 0 0 12 12 11 2 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 PVD35866.1 - 0.00043 20.5 65.5 0.0006 20.1 5.3 7.9 2 2 2 7 7 7 3 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 PVD35866.1 - 0.00071 19.3 2.9 0.011 15.5 0.1 11.7 15 0 0 15 15 13 5 zinc-finger C2H2-type zf-met PF12874.7 PVD35866.1 - 0.0011 19.2 93.9 0.17 12.3 0.2 15.4 16 0 0 16 16 16 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD35866.1 - 0.011 16.0 92.8 0.015 15.6 3.9 10.0 6 3 4 10 10 10 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 PVD35866.1 - 0.12 12.9 0.2 0.12 12.9 0.2 11.7 5 3 6 11 11 11 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2719 PF10891.8 PVD35866.1 - 0.23 11.4 6.7 6.8 6.7 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) DUF3268 PF11672.8 PVD35866.1 - 0.26 11.6 30.3 0.072 13.4 1.5 5.6 5 0 0 5 5 5 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 PVD35866.1 - 4.9 7.5 82.8 2.2 8.7 6.7 12.5 2 2 9 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 PVD35866.1 - 6.4 6.9 26.4 0.49 10.5 1.1 5.8 6 0 0 6 6 6 0 Zinc-finger domain WSC PF01822.19 PVD35867.1 - 2e-27 95.2 74.9 8.6e-10 38.7 4.1 7.7 7 0 0 7 7 7 6 WSC domain Lectin_C PF00059.21 PVD35867.1 - 6.1e-17 62.3 14.5 1.2e-09 38.9 2.0 5.4 6 1 1 7 7 7 3 Lectin C-type domain Sushi PF00084.20 PVD35867.1 - 7e-14 52.2 11.6 1.4e-08 35.2 2.9 3.8 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) F5_F8_type_C PF00754.25 PVD35867.1 - 2e-08 34.4 0.0 8.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain DUF5330 PF17264.2 PVD35867.1 - 0.17 11.9 1.3 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5330) Methyltransf_31 PF13847.6 PVD35868.1 - 3.3e-27 95.2 0.1 6.5e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD35868.1 - 3.7e-21 75.6 0.0 9.1e-21 74.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD35868.1 - 5.4e-20 71.8 0.0 9.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD35868.1 - 8.5e-19 67.8 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PVD35868.1 - 5.1e-16 59.0 0.0 6.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD35868.1 - 7.8e-16 58.6 0.0 2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD35868.1 - 3.2e-09 36.9 0.0 4.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PVD35868.1 - 3.8e-06 26.6 0.0 9.6e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PVD35868.1 - 4e-06 26.4 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PVD35868.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PVD35868.1 - 0.00027 20.4 0.0 0.00073 19.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 PVD35868.1 - 0.00083 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 PVD35868.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 PVD35868.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD35868.1 - 0.0033 16.4 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 PVD35868.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 PVD35868.1 - 0.037 13.1 0.1 0.31 10.1 0.0 2.3 2 1 1 3 3 3 0 Fibrillarin FtsJ PF01728.19 PVD35868.1 - 0.039 14.1 0.0 0.084 13.0 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase AdoMet_MTase PF07757.13 PVD35868.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 1 0 Predicted AdoMet-dependent methyltransferase UPF0020 PF01170.18 PVD35868.1 - 0.047 13.4 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 CheR PF01739.18 PVD35868.1 - 0.087 12.3 0.0 0.48 9.9 0.0 2.1 1 1 2 3 3 3 0 CheR methyltransferase, SAM binding domain DOT1 PF08123.13 PVD35868.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 PVD35868.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 PVD35870.1 - 1.4e-26 93.2 0.0 2.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD35870.1 - 1.9e-22 79.8 0.0 7.3e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD35870.1 - 3.7e-21 75.6 0.0 9.9e-21 74.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD35870.1 - 1.3e-18 67.2 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PVD35870.1 - 6.5e-15 55.7 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD35870.1 - 6.7e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD35870.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 PVD35870.1 - 5.7e-08 32.0 0.0 8.4e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 PVD35870.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 PVD35870.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD35870.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 PVD35870.1 - 0.00025 21.2 0.0 0.00062 19.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 PVD35870.1 - 0.00031 20.8 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PVD35870.1 - 0.00076 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.12 PVD35870.1 - 0.0094 15.6 0.1 0.021 14.4 0.1 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 PVD35870.1 - 0.029 12.9 0.0 0.069 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 PVD35870.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 PVD35870.1 - 0.065 13.2 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 PVD35870.1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Fibrillarin PF01269.17 PVD35870.1 - 0.07 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Flg_bbr_C PF06429.13 PVD35870.1 - 0.09 12.9 0.0 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal AdoMet_MTase PF07757.13 PVD35870.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase SRCR PF00530.18 PVD35871.1 - 1.6e-61 205.1 8.5 5.6e-26 91.0 0.9 3.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD35871.1 - 1.2e-16 61.1 2.8 0.00017 22.1 0.1 3.3 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD35871.1 - 7.3e-07 29.7 0.8 0.019 15.5 0.0 3.4 3 1 0 3 3 3 2 Hepsin, SRCR domain REGB_T4 PF10715.9 PVD35871.1 - 0.058 13.6 0.0 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 T4-page Endoribonuclease RegB SRCR PF00530.18 PVD35872.1 - 9.8e-48 160.8 8.6 4.1e-24 85.0 2.0 3.8 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD35872.1 - 1.2e-11 44.9 0.2 0.00055 20.4 0.1 4.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Ribosomal_L32p PF01783.23 PVD35872.1 - 0.0013 18.9 0.5 0.0045 17.2 0.5 2.0 1 0 0 1 1 1 1 Ribosomal L32p protein family Sulfotransfer_4 PF17784.1 PVD35872.1 - 0.093 12.5 0.1 0.54 10.1 0.1 2.2 3 0 0 3 3 3 0 Sulfotransferase domain Proteasome PF00227.26 PVD35873.1 - 6.1e-62 208.5 0.1 1.2e-61 207.6 0.1 1.4 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 PVD35873.1 - 2.8e-10 39.7 0.1 4.9e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.15 PVD35873.1 - 0.13 12.6 0.0 3.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain FAD-oxidase_C PF02913.19 PVD35874.1 - 4.9e-57 193.4 0.0 6.4e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PVD35874.1 - 3.1e-33 114.4 0.0 5.4e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Collagen PF01391.18 PVD35875.1 - 1.6e-164 533.8 690.1 6.8e-09 35.4 35.6 21.2 2 1 12 14 14 14 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 PVD35875.1 - 2e-60 204.0 0.1 3e-60 203.4 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 PVD35875.1 - 0.014 15.7 2.3 0.024 14.9 2.3 1.3 1 0 0 1 1 1 0 von Willebrand factor type C domain Collagen PF01391.18 PVD35876.1 - 3.9e-158 513.3 706.9 5.1e-09 35.8 36.9 20.4 1 1 9 10 10 10 6 Collagen triple helix repeat (20 copies) Pyridoxal_deC PF00282.19 PVD35876.1 - 4.2e-72 242.9 0.0 5.8e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain COLFI PF01410.18 PVD35876.1 - 4.4e-54 183.3 0.2 7.2e-54 182.5 0.2 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Aminotran_5 PF00266.19 PVD35876.1 - 0.00077 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PVD35876.1 - 0.0048 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_4 PF13637.6 PVD35879.1 - 2.3e-18 66.3 3.6 1.4e-11 44.7 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD35879.1 - 4.8e-18 65.5 1.2 5.7e-17 62.1 0.2 2.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD35879.1 - 6.9e-15 54.7 0.8 1.5e-06 28.3 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PVD35879.1 - 2.5e-14 53.2 0.2 2e-07 31.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35879.1 - 1.5e-11 43.4 0.5 0.00016 21.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat C2 PF00168.30 PVD35880.1 - 2.1e-58 195.0 7.8 9.3e-26 90.1 0.1 3.8 4 0 0 4 4 4 3 C2 domain SMP_LBD PF17047.5 PVD35880.1 - 2.7e-49 167.1 0.2 4.4e-49 166.4 0.2 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Peptidase_M41 PF01434.18 PVD35881.1 - 3.1e-64 216.3 1.7 6.9e-64 215.2 1.7 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PVD35881.1 - 1.3e-42 145.4 0.0 3.1e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD35881.1 - 3.5e-10 39.5 0.1 9e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD35881.1 - 9.9e-07 28.8 0.1 1.5e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PVD35881.1 - 2.1e-05 24.3 0.0 8.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PVD35881.1 - 3.8e-05 24.1 0.3 0.0008 19.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD35881.1 - 0.001 19.3 0.1 0.091 13.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 PVD35881.1 - 0.0017 17.7 0.1 0.0049 16.1 0.0 1.7 1 1 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 PVD35881.1 - 0.0034 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PVD35881.1 - 0.014 15.1 0.2 0.04 13.7 0.2 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 PVD35881.1 - 0.017 15.3 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PVD35881.1 - 0.035 13.5 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PVD35881.1 - 0.04 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain CSTF2_hinge PF14327.6 PVD35881.1 - 0.054 14.0 0.5 0.19 12.2 0.1 2.2 2 0 0 2 2 1 0 Hinge domain of cleavage stimulation factor subunit 2 AAA_7 PF12775.7 PVD35881.1 - 0.062 12.8 0.0 0.34 10.4 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 PVD35881.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 PVD35881.1 - 0.1 13.0 0.2 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD35881.1 - 0.14 12.0 0.0 0.48 10.3 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 PVD35881.1 - 0.19 12.0 0.4 0.51 10.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain FIVAR PF07554.13 PVD35881.1 - 1.8 9.4 4.5 1.4 9.8 0.3 3.1 4 0 0 4 4 2 0 FIVAR domain TPR_12 PF13424.6 PVD35882.1 - 0.0058 16.9 5.4 0.25 11.6 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35882.1 - 0.023 15.4 0.1 7.2 7.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 PVD35882.1 - 0.036 12.8 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 PVD35882.1 - 0.038 14.6 0.1 52 4.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35883.1 - 6.7e-27 91.4 16.9 2.3 8.5 0.0 23.0 24 0 0 24 24 23 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35883.1 - 1.5e-20 73.5 1.1 1.1 9.8 0.0 13.8 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35883.1 - 2.8e-20 71.2 0.2 0.17 12.4 0.0 11.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35883.1 - 1.2e-19 69.2 23.4 2.5 8.1 0.1 19.7 22 0 0 22 22 22 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35883.1 - 7.4e-19 66.8 3.3 0.78 10.7 0.0 16.6 15 5 4 19 19 15 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35883.1 - 1.1e-16 60.3 0.0 4.2 7.1 0.0 12.2 9 4 4 13 13 13 4 TPR repeat TPR_8 PF13181.6 PVD35883.1 - 2.1e-16 58.7 10.5 12 6.4 0.0 16.6 17 0 0 17 17 17 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35883.1 - 2.5e-16 59.1 0.6 6.1 7.7 0.0 14.4 13 1 1 14 14 14 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35883.1 - 9.5e-14 51.5 12.4 9.7 6.6 0.0 15.0 15 2 2 17 17 14 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35883.1 - 2.4e-08 34.5 0.0 18 6.1 0.0 11.2 17 0 0 17 17 9 0 Tetratricopeptide repeat DUF2225 PF09986.9 PVD35883.1 - 3.5e-07 30.2 5.0 1.5 8.5 0.0 5.7 5 0 0 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 PVD35883.1 - 6.6e-07 29.4 2.9 9.7 6.4 0.1 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD35883.1 - 8.1e-06 26.1 1.0 31 5.0 0.0 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD35883.1 - 1.3e-05 25.2 4.7 0.98 9.5 0.2 5.4 3 2 1 4 4 4 1 Putative TPR-like repeat DUF4810 PF16068.5 PVD35883.1 - 4.6e-05 23.9 1.0 23 5.6 0.0 6.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4810) TPR_10 PF13374.6 PVD35883.1 - 0.00059 19.6 16.1 1.6e+02 2.3 0.0 13.3 16 0 0 16 16 15 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD35883.1 - 0.0011 18.8 21.4 9.5 6.5 0.0 11.9 15 0 0 15 15 11 0 Tetratricopeptide repeat HTH_Bact PF18768.1 PVD35883.1 - 0.015 14.8 0.1 12 5.6 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain NAD_binding_6 PF08030.12 PVD35883.1 - 0.11 12.7 3.4 1.6 8.8 0.0 3.1 3 1 0 3 3 3 0 Ferric reductase NAD binding domain DUF4543 PF15076.6 PVD35883.1 - 0.13 12.4 0.1 45 4.3 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) NES_C_h PF18208.1 PVD35883.1 - 0.74 10.1 5.8 7.8 6.8 0.1 4.7 4 0 0 4 4 4 0 Nicking enzyme C-terminal middle helical domain RsbU_N PF08673.10 PVD35883.1 - 1 9.5 3.0 12 6.0 0.1 4.1 4 0 0 4 4 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Mac PF12464.8 PVD35883.1 - 1.4 9.2 14.2 5 7.4 0.7 5.6 5 0 0 5 5 5 0 Maltose acetyltransferase PulG PF11773.8 PVD35883.1 - 2.1 8.2 4.3 43 4.0 0.1 3.6 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin TPR_8 PF13181.6 PVD35884.1 - 1.8e-08 33.9 0.1 0.52 10.7 0.0 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35884.1 - 2.6e-08 34.0 2.9 0.074 13.3 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35884.1 - 1.1e-07 32.1 0.8 0.78 10.7 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35884.1 - 1.8e-07 31.5 0.3 0.058 13.9 0.0 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35884.1 - 2.8e-07 30.1 0.8 0.022 14.6 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35884.1 - 7.9e-07 28.7 0.9 0.69 10.2 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35884.1 - 1.4e-05 25.4 0.3 3.2 8.6 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35884.1 - 0.00092 18.8 0.2 0.25 11.0 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 PVD35884.1 - 0.0011 19.6 0.0 1.6 9.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 PVD35884.1 - 0.036 13.0 0.3 0.98 8.3 0.1 2.2 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 PVD35884.1 - 0.043 14.2 3.9 0.37 11.3 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD35884.1 - 0.27 11.2 0.1 0.27 11.2 0.1 4.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35885.1 - 2.3e-12 46.0 3.7 0.81 9.9 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35885.1 - 4.8e-11 42.0 0.1 1.2 9.5 0.0 7.5 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35885.1 - 1.1e-10 40.9 0.9 0.25 11.2 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35885.1 - 8.8e-08 32.0 0.0 0.07 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35885.1 - 2.1e-07 31.2 3.3 1.7 9.6 0.0 7.1 5 3 3 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35885.1 - 1.5e-06 28.4 6.9 0.34 11.2 0.0 6.7 5 3 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35885.1 - 2.5e-06 27.9 0.0 0.065 13.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35885.1 - 2.5e-06 27.0 0.3 0.57 9.9 0.1 4.9 2 2 2 4 4 4 2 TPR repeat TPR_7 PF13176.6 PVD35885.1 - 0.0001 22.0 0.4 4.2 7.6 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35885.1 - 0.00092 19.7 0.1 45 5.0 0.0 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD35885.1 - 0.0015 18.4 8.9 2.5 8.1 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35885.1 - 0.0019 18.8 0.0 0.64 10.7 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 PVD35885.1 - 0.0026 17.5 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 PVD35885.1 - 0.0072 16.5 0.0 11 6.2 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 PVD35885.1 - 0.0081 16.7 0.2 1.1 9.8 0.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4810) TPR_20 PF14561.6 PVD35885.1 - 0.041 14.2 0.4 1.1 9.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat SMBP PF16785.5 PVD35885.1 - 0.046 14.0 0.3 0.17 12.2 0.2 2.0 2 0 0 2 2 1 0 Small metal-binding protein TcdB_N PF12918.7 PVD35885.1 - 2.2 8.7 6.7 2.1 8.7 0.2 3.2 2 1 0 3 3 3 0 TcdB toxin N-terminal helical domain TPR_1 PF00515.28 PVD35886.1 - 3.3e-10 39.3 0.4 0.28 11.1 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35886.1 - 7.6e-10 38.2 4.8 0.47 10.7 0.0 7.8 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35886.1 - 1.4e-08 34.9 6.6 0.27 11.5 0.0 5.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35886.1 - 5.7e-08 32.4 2.3 0.62 10.4 0.0 7.2 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD35886.1 - 2.5e-06 27.1 0.6 0.33 11.1 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35886.1 - 1.6e-05 24.5 0.0 0.0015 18.2 0.0 3.6 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 PVD35886.1 - 4.1e-05 24.0 1.8 27 5.9 0.0 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35886.1 - 4.6e-05 23.8 4.4 20 6.1 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD35886.1 - 4.7e-05 23.8 0.0 3.3 8.3 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 PVD35886.1 - 7.9e-05 22.4 3.6 0.22 11.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35886.1 - 0.00046 20.4 0.5 7.6 7.2 0.0 4.8 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35886.1 - 0.001 19.7 0.0 2.4 8.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 PVD35886.1 - 0.018 15.6 0.0 0.15 12.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Conotoxin PF02950.17 PVD35886.1 - 0.65 11.1 3.6 0.39 11.8 0.2 2.3 2 0 0 2 2 2 0 Conotoxin PX PF00787.24 PVD35887.1 - 8.2e-23 80.5 1.0 2.3e-22 79.1 0.0 2.3 3 0 0 3 3 3 1 PX domain FAM92 PF06730.11 PVD35887.1 - 3.3e-05 23.4 0.6 3.3e-05 23.4 0.6 2.0 2 1 0 2 2 2 1 FAM92 protein Vps5 PF09325.10 PVD35887.1 - 0.0081 15.7 5.8 0.0081 15.7 5.8 2.2 1 1 1 2 2 2 2 Vps5 C terminal like DNA_pol_B_exo1 PF03104.19 PVD35887.1 - 0.044 12.9 0.2 0.24 10.5 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain Hormone_3 PF00159.18 PVD35887.1 - 0.13 12.3 2.2 1.6 8.9 0.8 2.9 2 0 0 2 2 2 0 Pancreatic hormone peptide TetR_C_18 PF17923.1 PVD35890.1 - 0.12 12.9 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-C2H2_4 PF13894.6 PVD35891.1 - 3.5e-11 43.0 16.2 0.00053 20.6 0.4 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD35891.1 - 3.1e-09 36.8 17.1 0.00014 22.1 0.8 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD35891.1 - 5.4e-06 26.6 8.3 0.0032 17.7 0.2 3.7 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PVD35891.1 - 1.9e-05 24.8 14.8 0.0086 16.5 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 PVD35891.1 - 0.022 15.1 5.0 0.022 15.1 5.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 PVD35891.1 - 0.024 14.9 0.9 6 7.2 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_7 PF15269.6 PVD35891.1 - 0.024 14.7 1.5 0.92 9.6 0.3 2.5 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.7 PVD35891.1 - 0.059 13.7 12.1 2.4 8.5 0.3 3.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2039 PF10217.9 PVD35891.1 - 0.067 13.5 1.5 0.39 11.1 0.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C2H2_11 PF16622.5 PVD35891.1 - 0.068 12.9 3.3 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type BHD_1 PF10403.9 PVD35891.1 - 0.088 12.7 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 zf-met PF12874.7 PVD35891.1 - 0.16 12.4 15.9 0.2 12.1 0.7 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 PVD35891.1 - 0.18 11.7 1.7 0.34 10.8 0.2 2.0 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 PVD35891.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PVD35891.1 - 0.33 10.9 2.0 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 PVD35891.1 - 0.38 10.6 4.9 0.51 10.2 1.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 PVD35891.1 - 0.49 10.0 5.8 0.71 9.5 0.4 2.7 3 0 0 3 3 2 0 Ubiquitin-Binding Zinc Finger PHD_4 PF16866.5 PVD35891.1 - 0.54 10.4 9.7 0.18 12.0 0.8 2.9 3 0 0 3 3 2 0 PHD-finger zf-met2 PF12907.7 PVD35891.1 - 0.71 10.1 3.9 2.5 8.3 0.4 2.7 2 1 0 2 2 2 0 Zinc-binding Zn-ribbon_8 PF09723.10 PVD35891.1 - 1 9.5 4.5 0.71 10.0 0.1 2.7 2 1 1 3 3 3 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 PVD35892.1 - 5.9e-16 58.1 18.3 1.1e-06 28.8 5.6 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 PVD35892.1 - 1e-11 44.6 27.7 0.0008 19.7 1.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type Homeodomain PF00046.29 PVD35892.1 - 1.4e-06 28.0 0.3 5.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Homeodomain zf-C2H2_jaz PF12171.8 PVD35892.1 - 0.00023 21.4 16.9 0.067 13.5 1.7 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PVD35892.1 - 0.00027 21.5 31.4 0.026 15.4 0.9 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD35892.1 - 0.00057 19.6 6.1 0.037 13.8 1.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD35892.1 - 0.0022 17.9 1.4 0.0022 17.9 1.4 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf_UBZ PF18439.1 PVD35892.1 - 0.0052 16.4 10.6 0.93 9.1 0.2 3.6 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 PVD35892.1 - 0.02 15.3 19.0 0.91 10.0 2.9 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BolA PF01722.18 PVD35892.1 - 0.082 13.2 2.2 0.5 10.7 2.2 2.4 1 1 0 1 1 1 0 BolA-like protein zf-C2HC_2 PF13913.6 PVD35892.1 - 0.15 12.0 7.3 4.5 7.3 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.22 PVD35892.1 - 0.15 12.3 13.5 1.5 9.1 4.0 2.7 1 1 1 2 2 2 0 LIM domain zf-AN1 PF01428.16 PVD35892.1 - 1.3 9.2 14.3 4.6 7.5 0.2 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.5 PVD35892.1 - 1.5 9.6 9.2 1.5e+02 3.2 9.2 2.9 1 1 0 1 1 1 0 zinc-ribbon family zf-MYST PF17772.1 PVD35892.1 - 6.7 6.4 8.8 12 5.6 0.3 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 PVD35892.1 - 9 6.5 11.6 5.9 7.1 0.8 3.0 1 1 2 3 3 3 0 Zinc ribbon domain Sgf11 PF08209.11 PVD35893.1 - 3.4e-15 55.3 3.7 8.2e-15 54.1 3.7 1.7 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 PVD35893.1 - 2e-06 27.6 0.8 5e-06 26.3 0.8 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain Ebp2 PF05890.12 PVD35893.1 - 0.019 14.5 2.3 0.037 13.6 2.3 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 WCCH PF03716.14 PVD35893.1 - 0.022 14.4 0.7 0.065 12.9 0.7 1.8 1 0 0 1 1 1 0 WCCH motif Band_3_cyto PF07565.13 PVD35893.1 - 0.095 12.5 4.3 0.21 11.3 4.3 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_C50 PF03568.17 PVD35894.1 - 9.7e-79 265.3 1.9 5.6e-78 262.8 1.9 2.3 1 1 0 1 1 1 1 Peptidase family C50 DUF3617 PF12276.8 PVD35894.1 - 0.021 15.1 0.9 0.054 13.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) zf-RING_2 PF13639.6 PVD35895.1 - 4.2e-15 55.8 23.4 8.3e-09 35.7 4.9 3.4 3 0 0 3 3 3 3 Ring finger domain zf-RING_5 PF14634.6 PVD35895.1 - 1.9e-11 43.8 21.8 3.4e-06 26.9 5.0 3.4 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD35895.1 - 8.8e-10 38.3 20.2 7.5e-06 25.7 4.3 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD35895.1 - 1.4e-09 38.1 21.8 3.5e-06 27.2 2.5 3.7 3 1 1 4 4 4 2 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD35895.1 - 2e-09 37.0 18.7 1.5e-05 24.6 3.5 3.7 3 0 0 3 3 3 2 RING-like zinc finger Prok-RING_4 PF14447.6 PVD35895.1 - 2.2e-09 37.0 18.0 4.9e-06 26.3 3.1 3.7 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD35895.1 - 6.7e-08 32.5 13.0 0.00046 20.2 2.6 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PVD35895.1 - 3.6e-07 29.9 24.4 0.00011 22.0 4.1 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD35895.1 - 6.2e-07 29.1 24.1 0.002 17.9 5.4 4.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD35895.1 - 1e-06 28.6 27.0 3e-06 27.2 3.8 4.3 3 1 1 4 4 4 2 RING-type zinc-finger IQ PF00612.27 PVD35895.1 - 2.2e-06 27.0 1.1 5.9e-06 25.6 1.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zn_ribbon_17 PF17120.5 PVD35895.1 - 0.026 14.2 17.7 0.055 13.1 2.7 3.2 3 1 0 3 3 3 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PVD35895.1 - 0.053 13.4 11.9 0.21 11.5 3.6 3.0 2 0 0 2 2 2 0 PHD-finger Rad50_zn_hook PF04423.14 PVD35895.1 - 0.059 13.2 6.3 18 5.3 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PVD35895.1 - 0.11 12.3 17.9 0.3 10.9 4.4 3.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 PVD35895.1 - 0.42 11.1 13.4 3.3 8.2 0.1 4.2 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-Nse PF11789.8 PVD35895.1 - 0.53 10.2 12.4 1.8 8.4 1.3 3.4 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 PVD35895.1 - 2.2 8.7 18.8 0.29 11.5 4.5 3.6 3 0 0 3 3 3 0 RING-like domain zf-UDP PF14569.6 PVD35895.1 - 2.4 8.3 15.0 0.078 13.1 2.1 3.2 3 0 0 3 3 3 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 PVD35895.1 - 3.9 7.7 20.2 1.2 9.4 4.4 3.8 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 PVD35895.1 - 4.9 7.3 19.1 1.1 9.4 0.3 3.7 3 2 1 4 4 4 0 KIAA1045 RING finger Kelch_1 PF01344.25 PVD35896.1 - 2.4e-91 299.1 12.0 2.6e-16 58.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD35896.1 - 4.4e-44 147.4 1.9 1.1e-06 28.7 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PVD35896.1 - 1.4e-39 132.6 4.0 1.3e-06 28.1 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 PVD35896.1 - 5.9e-31 106.6 0.4 5.9e-31 106.6 0.4 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 PVD35896.1 - 8.2e-31 106.5 0.1 2e-30 105.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PVD35896.1 - 1.5e-23 82.6 1.9 0.0009 19.5 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PVD35896.1 - 3.3e-23 81.4 0.1 0.0081 16.2 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD35896.1 - 2.4e-07 30.6 9.8 0.22 11.5 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 PVD35896.1 - 0.00014 22.0 0.3 0.0061 16.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 PVD35896.1 - 0.062 13.8 6.2 20 5.8 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain EGF_CA PF07645.15 PVD35898.1 - 5.5e-16 58.5 28.3 3.4e-13 49.6 7.3 6.9 5 1 1 6 6 6 3 Calcium-binding EGF domain cEGF PF12662.7 PVD35898.1 - 2.3e-10 40.2 45.8 1.9e-05 24.5 2.0 6.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD35898.1 - 2.3e-08 34.1 21.0 8.1e-07 29.1 6.4 7.6 6 0 0 6 6 6 4 EGF domain EGF_MSP1_1 PF12946.7 PVD35898.1 - 1.8e-05 24.7 46.8 9.9e-05 22.3 5.6 6.5 6 0 0 6 6 6 3 MSP1 EGF domain 1 FXa_inhibition PF14670.6 PVD35898.1 - 5.8e-05 23.3 8.8 5.8e-05 23.3 8.8 6.9 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD35898.1 - 0.0005 20.3 5.6 0.0005 20.3 5.6 7.9 7 0 0 7 7 7 4 EGF-like domain hEGF PF12661.7 PVD35898.1 - 0.018 15.7 5.8 0.018 15.7 5.8 9.5 9 1 1 10 10 10 0 Human growth factor-like EGF EGF_CA PF07645.15 PVD35899.1 - 3.6e-98 321.5 372.7 2.3e-11 43.7 10.6 21.7 22 0 0 22 22 22 16 Calcium-binding EGF domain EGF_3 PF12947.7 PVD35899.1 - 1.3e-61 204.4 372.0 7.4e-11 42.1 11.1 22.9 24 0 0 24 24 24 15 EGF domain cEGF PF12662.7 PVD35899.1 - 8.9e-32 108.7 222.6 8.4e-05 22.4 3.7 20.1 19 0 0 19 19 19 14 Complement Clr-like EGF-like EGF PF00008.27 PVD35899.1 - 9.2e-18 64.2 321.1 3.5e-05 24.0 6.9 23.9 23 0 0 23 23 23 14 EGF-like domain VWD PF00094.25 PVD35899.1 - 5.6e-17 62.4 0.0 1.4e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_MSP1_1 PF12946.7 PVD35899.1 - 1.8e-15 56.6 264.4 0.0019 18.2 6.5 20.2 19 0 0 19 19 19 14 MSP1 EGF domain 1 TIL PF01826.17 PVD35899.1 - 8.3e-05 22.8 9.0 8.3e-05 22.8 9.0 23.8 10 3 15 25 25 25 2 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.6 PVD35899.1 - 9.2e-05 22.6 30.7 0.00037 20.7 11.6 23.6 22 2 1 23 23 23 14 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 PVD35899.1 - 0.0055 17.0 17.5 0.0066 16.7 5.8 22.3 14 4 6 20 20 20 10 Pvs28 EGF domain GKAP PF03359.13 PVD35900.1 - 1.7e-41 142.9 1.1 1.7e-41 142.9 1.1 4.1 3 1 0 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein PMSR PF01625.21 PVD35901.1 - 9.9e-68 227.1 2.3 1.2e-67 226.8 2.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cullin PF00888.22 PVD35902.1 - 1.2e-174 582.4 17.3 3.3e-166 554.5 10.2 2.3 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 PVD35902.1 - 1.1e-28 99.1 2.0 3.1e-28 97.6 2.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 PVD35902.1 - 0.01 16.2 1.0 0.08 13.4 0.1 2.8 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC Rrf2 PF02082.20 PVD35902.1 - 0.12 12.8 0.9 0.56 10.6 0.2 2.4 2 1 1 3 3 3 0 Transcriptional regulator FAM194 PF14977.6 PVD35902.1 - 0.31 10.3 2.4 5.5 6.3 0.0 2.5 2 0 0 2 2 2 0 FAM194 protein DUF4355 PF14265.6 PVD35902.1 - 1.7 8.9 6.9 0.41 10.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DAZAP2 PF11029.8 PVD35903.1 - 1.6e-05 25.8 23.2 6.1e-05 23.9 23.2 1.8 1 1 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) SKG6 PF08693.10 PVD35904.1 - 0.00062 19.1 1.5 0.0011 18.3 1.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF515 PF04415.12 PVD35904.1 - 0.01 14.3 0.0 0.013 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mid2 PF04478.12 PVD35904.1 - 0.073 12.9 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TraL PF07178.11 PVD35904.1 - 0.085 13.3 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 TraL protein EGF_CA PF07645.15 PVD35905.1 - 2.7e-46 155.5 204.2 1e-09 38.4 5.3 22.2 13 7 7 20 20 20 11 Calcium-binding EGF domain EGF_3 PF12947.7 PVD35905.1 - 2.2e-08 34.2 87.4 0.00035 20.7 3.4 22.7 19 4 2 21 21 21 10 EGF domain cEGF PF12662.7 PVD35905.1 - 1.5e-07 31.2 19.8 4.1e-05 23.4 1.4 23.6 25 4 0 25 25 25 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD35905.1 - 4.6e-07 30.0 72.5 5.7e-05 23.3 8.3 20.4 17 3 3 20 20 20 10 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 PVD35905.1 - 7e-05 22.8 15.9 0.00068 19.6 5.7 18.8 20 5 4 24 24 24 4 MSP1 EGF domain 1 hEGF PF12661.7 PVD35905.1 - 0.00034 21.1 5.1 0.00034 21.1 5.1 29.0 31 0 0 31 31 31 11 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 PVD35905.1 - 0.007 16.7 3.1 0.007 16.7 3.1 21.3 13 4 5 18 18 18 2 Pvs28 EGF domain EGF_CA PF07645.15 PVD35906.1 - 9.7e-31 105.7 159.1 7e-10 38.9 9.3 10.6 9 1 1 10 10 10 6 Calcium-binding EGF domain cEGF PF12662.7 PVD35906.1 - 3.6e-29 100.3 95.7 5.8e-08 32.5 0.9 10.3 11 0 0 11 11 11 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD35906.1 - 1.2e-24 86.2 152.8 7.8e-11 42.1 8.4 10.2 9 1 1 10 10 10 6 Coagulation Factor Xa inhibitory site VWD PF00094.25 PVD35906.1 - 9.9e-18 64.9 0.0 2.9e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain NIDO PF06119.14 PVD35906.1 - 2.4e-06 28.4 0.5 6.2e-05 23.9 0.1 2.8 1 1 1 2 2 2 1 Nidogen-like SEA PF01390.20 PVD35906.1 - 1.2e-05 25.3 0.6 5.2e-05 23.3 0.6 2.1 1 0 0 1 1 1 1 SEA domain EGF PF00008.27 PVD35906.1 - 1.2e-05 25.5 15.7 0.00044 20.5 6.8 10.7 10 0 0 10 10 10 6 EGF-like domain EGF_2 PF07974.13 PVD35906.1 - 0.013 15.9 7.3 0.013 15.9 7.3 10.8 9 2 2 11 11 11 0 EGF-like domain OEP PF02321.18 PVD35906.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein EGF_CA PF07645.15 PVD35907.1 - 2.6e-21 75.5 54.0 5.2e-10 39.4 10.5 10.0 5 2 3 8 8 8 4 Calcium-binding EGF domain EGF_3 PF12947.7 PVD35907.1 - 0.00014 22.0 27.5 0.00037 20.6 11.6 8.7 7 1 1 8 8 8 4 EGF domain EGF_MSP1_1 PF12946.7 PVD35907.1 - 0.00027 20.9 19.4 0.0025 17.8 5.5 7.7 8 1 1 9 9 9 2 MSP1 EGF domain 1 SKG6 PF08693.10 PVD35907.1 - 0.001 18.5 1.5 0.0019 17.6 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain cEGF PF12662.7 PVD35907.1 - 0.0035 17.2 1.9 0.0035 17.2 1.9 9.2 10 0 0 10 10 10 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD35907.1 - 0.0065 16.7 10.4 0.0065 16.7 10.4 9.1 6 3 2 8 8 8 3 Coagulation Factor Xa inhibitory site hEGF PF12661.7 PVD35907.1 - 0.013 16.1 2.8 0.013 16.1 2.8 12.3 13 1 1 14 14 14 0 Human growth factor-like EGF EGF_CA PF07645.15 PVD35908.1 - 1.9e-25 88.8 71.2 1.5e-08 34.7 7.8 11.6 5 3 5 10 10 10 5 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 PVD35908.1 - 1.5e-05 24.9 16.5 0.00024 21.1 4.5 10.6 11 1 1 12 12 12 4 MSP1 EGF domain 1 EGF_3 PF12947.7 PVD35908.1 - 0.0007 19.7 37.4 0.0045 17.1 7.8 12.5 7 5 3 10 10 10 5 EGF domain Laminin_EGF PF00053.24 PVD35908.1 - 0.0062 16.6 12.1 0.0062 16.6 12.1 13.4 3 2 8 11 11 11 5 Laminin EGF domain hEGF PF12661.7 PVD35908.1 - 0.0065 17.1 19.0 0.013 16.1 5.3 16.1 16 1 1 17 17 17 8 Human growth factor-like EGF EGF_2 PF07974.13 PVD35908.1 - 0.042 14.2 6.8 0.042 14.2 6.8 15.1 14 2 2 16 16 16 0 EGF-like domain P3A PF08727.11 PVD35908.1 - 0.16 11.4 3.0 5 6.6 0.3 2.8 2 0 0 2 2 2 0 Poliovirus 3A protein like GBP_PSP PF02425.15 PVD35908.1 - 3.9 7.2 17.1 23 4.7 0.7 5.4 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide EGF_CA PF07645.15 PVD35909.1 - 9.3e-97 317.0 846.0 1.3e-09 38.0 11.0 47.5 33 11 12 45 45 45 26 Calcium-binding EGF domain cEGF PF12662.7 PVD35909.1 - 2.4e-45 152.0 423.4 1.7e-08 34.2 0.5 44.6 43 0 0 43 43 43 28 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD35909.1 - 1.9e-27 95.2 143.4 8.4e-12 45.2 12.3 45.7 32 11 11 43 43 43 22 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 PVD35909.1 - 6.7e-05 22.8 31.9 0.00013 21.9 8.4 39.3 46 1 1 47 47 47 9 MSP1 EGF domain 1 EGF_3 PF12947.7 PVD35909.1 - 7.6e-05 22.8 34.6 0.001 19.2 5.8 49.3 38 9 7 45 45 45 23 EGF domain SEA PF01390.20 PVD35909.1 - 0.00035 20.6 1.1 0.00069 19.7 1.1 1.5 1 0 0 1 1 1 1 SEA domain hEGF PF12661.7 PVD35909.1 - 0.0098 16.5 2.0 0.0098 16.5 2.0 57.0 58 3 1 59 59 59 25 Human growth factor-like EGF NIDO PF06119.14 PVD35910.1 - 4.2e-12 46.8 0.3 2.1e-11 44.6 0.3 2.3 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 PVD35910.1 - 1.4e-08 35.2 0.0 4.5e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain Big_9 PF17963.1 PVD35910.1 - 0.0082 16.9 6.7 0.041 14.6 6.7 2.3 1 0 0 1 1 1 1 Bacterial Ig domain EGF_CA PF07645.15 PVD35911.1 - 4.9e-75 247.5 295.4 2e-09 37.5 6.2 43.0 28 12 15 43 43 43 18 Calcium-binding EGF domain EGF_3 PF12947.7 PVD35911.1 - 2.5e-06 27.6 49.8 0.00036 20.7 5.5 42.9 34 8 5 39 39 39 15 EGF domain SEA PF01390.20 PVD35911.1 - 0.0013 18.8 7.2 0.23 11.6 0.1 3.4 3 0 0 3 3 3 2 SEA domain hEGF PF12661.7 PVD35911.1 - 0.0026 18.3 23.8 0.004 17.7 3.8 52.3 53 1 0 53 53 53 27 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 PVD35911.1 - 0.0029 17.6 16.9 0.0044 17.0 4.6 30.7 35 3 1 36 36 36 13 MSP1 EGF domain 1 Laminin_EGF PF00053.24 PVD35911.1 - 0.0046 17.1 8.3 0.0046 17.1 8.3 41.3 10 8 29 39 39 39 15 Laminin EGF domain Acyl_transf_3 PF01757.22 PVD35912.1 - 2.7e-15 56.3 34.9 3.4e-15 56.0 34.9 1.1 1 0 0 1 1 1 1 Acyltransferase family CUB PF00431.20 PVD35915.1 - 1.5e-107 353.6 6.8 1.5e-20 73.6 0.0 8.3 8 0 0 8 8 8 8 CUB domain RE_MamI PF09567.10 PVD35915.1 - 0.045 13.4 1.3 33 4.1 0.0 3.7 4 0 0 4 4 4 0 MamI restriction endonuclease DUF2333 PF10095.9 PVD35915.1 - 2 7.4 4.7 9.3 5.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) CUB PF00431.20 PVD35916.1 - 9.2e-52 174.0 0.2 1.2e-19 70.7 0.0 3.6 3 0 0 3 3 3 3 CUB domain THAP PF05485.12 PVD35916.1 - 0.00022 22.1 0.0 0.00063 20.6 0.0 1.8 1 0 0 1 1 1 1 THAP domain DDE_Tnp_1_7 PF13843.6 PVD35917.1 - 1.3e-23 83.9 0.0 2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 CUB PF00431.20 PVD35917.1 - 1.9e-19 70.0 4.0 9e-09 35.7 0.3 3.6 3 0 0 3 3 3 3 CUB domain SieB PF14163.6 PVD35918.1 - 0.057 12.9 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B CUB PF00431.20 PVD35919.1 - 1.1e-69 231.7 3.2 2.8e-22 79.1 0.0 5.2 5 0 0 5 5 5 5 CUB domain CUB_2 PF02408.20 PVD35919.1 - 0.041 13.7 12.0 0.14 12.0 0.3 5.3 7 1 0 7 7 7 0 CUB-like domain CUB PF00431.20 PVD35920.1 - 2.7e-63 211.1 0.5 4.4e-20 72.1 0.0 4.5 3 1 1 4 4 4 4 CUB domain CUB PF00431.20 PVD35921.1 - 4.4e-121 397.2 9.1 1e-28 99.9 0.0 7.5 7 0 0 7 7 7 7 CUB domain EGF_CA PF07645.15 PVD35921.1 - 1.3e-16 60.5 45.8 5.4e-09 36.1 9.5 6.6 5 1 1 6 6 6 3 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 PVD35921.1 - 0.0002 21.3 3.6 0.0002 21.3 3.6 5.8 5 1 1 6 6 6 2 MSP1 EGF domain 1 FXa_inhibition PF14670.6 PVD35921.1 - 0.012 15.9 10.9 0.012 15.9 10.9 6.5 2 1 3 5 5 5 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD35921.1 - 0.013 15.8 2.3 0.013 15.8 2.3 6.8 6 0 0 6 6 6 0 EGF-like domain Ribosomal_L10 PF00466.20 PVD35921.1 - 0.23 11.6 0.1 0.43 10.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L10 CUB PF00431.20 PVD35922.1 - 8.1e-295 956.4 60.9 7.7e-29 100.2 0.0 22.2 21 0 0 21 21 21 21 CUB domain EGF_CA PF07645.15 PVD35922.1 - 1.1e-84 278.4 618.7 1.8e-08 34.4 8.2 38.4 34 4 4 38 38 38 24 Calcium-binding EGF domain cEGF PF12662.7 PVD35922.1 - 2.7e-66 219.0 358.0 1.3e-07 31.4 1.8 39.8 38 0 0 38 38 38 25 Complement Clr-like EGF-like 7tm_1 PF00001.21 PVD35922.1 - 2.4e-18 66.4 1.1 5.3e-18 65.3 1.1 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FXa_inhibition PF14670.6 PVD35922.1 - 1e-16 60.9 601.0 4.4e-06 26.9 7.2 38.8 29 6 10 39 39 39 22 Coagulation Factor Xa inhibitory site NIDO PF06119.14 PVD35922.1 - 4.3e-07 30.8 0.7 3.7e-06 27.8 0.3 3.0 2 0 0 2 2 2 1 Nidogen-like EGF_3 PF12947.7 PVD35922.1 - 0.00025 21.2 17.6 0.00056 20.1 4.4 38.5 35 6 4 39 39 39 14 EGF domain EGF_MSP1_1 PF12946.7 PVD35922.1 - 0.00063 19.7 3.2 0.00063 19.7 3.2 28.5 29 2 2 31 31 31 4 MSP1 EGF domain 1 hEGF PF12661.7 PVD35922.1 - 0.0026 18.3 4.7 0.0026 18.3 4.7 37.2 37 2 0 37 37 37 11 Human growth factor-like EGF SusD_RagB PF07980.11 PVD35922.1 - 0.57 9.7 7.0 27 4.3 0.1 3.8 3 0 0 3 3 3 0 SusD family Methyltransf_3 PF01596.17 PVD35923.1 - 1.8e-37 128.6 0.0 3.2e-37 127.8 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_24 PF13578.6 PVD35923.1 - 4.8e-08 34.0 0.0 8.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD35923.1 - 0.00096 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PVD35923.1 - 0.047 14.4 0.1 0.12 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.17 PVD35923.1 - 0.047 13.1 0.2 0.37 10.2 0.1 2.3 2 1 0 2 2 2 0 Spermine/spermidine synthase domain TPR_19 PF14559.6 PVD35924.1 - 1.1e-52 176.4 58.8 1.4e-06 28.7 1.2 17.4 13 4 3 18 18 17 12 Tetratricopeptide repeat TPR_2 PF07719.17 PVD35924.1 - 1.1e-44 147.0 51.8 0.00012 21.9 0.0 20.3 20 0 0 20 20 20 10 Tetratricopeptide repeat TPR_14 PF13428.6 PVD35924.1 - 2.7e-41 136.7 33.7 0.00037 21.1 0.0 19.9 14 5 4 18 18 18 5 Tetratricopeptide repeat TPR_16 PF13432.6 PVD35924.1 - 1.6e-28 99.1 27.9 1.9e-05 25.2 0.0 14.6 15 3 1 16 16 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD35924.1 - 1.8e-27 93.2 40.3 3.3e-05 23.8 0.0 16.0 17 0 0 17 17 16 6 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD35924.1 - 1.1e-25 89.6 35.3 0.0079 16.4 0.0 13.3 11 4 2 14 14 13 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PVD35924.1 - 1.1e-24 84.5 30.2 0.00021 21.1 0.0 13.9 15 0 0 15 15 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 PVD35924.1 - 9.7e-24 83.5 46.1 2.8e-06 27.5 5.7 15.3 13 4 3 16 16 16 4 Tetratricopeptide repeat TPR_1 PF00515.28 PVD35924.1 - 2e-23 81.2 66.8 4.9e-05 23.0 0.0 17.8 19 0 0 19 19 17 7 Tetratricopeptide repeat TPR_17 PF13431.6 PVD35924.1 - 9.7e-20 69.5 26.8 0.082 13.3 0.1 15.4 18 1 0 18 18 13 4 Tetratricopeptide repeat TPR_11 PF13414.6 PVD35924.1 - 6.3e-18 64.2 24.4 1.9e-05 24.2 0.0 11.2 10 2 2 12 12 11 3 TPR repeat TPR_15 PF13429.6 PVD35924.1 - 7.4e-13 48.3 38.0 0.00083 18.7 4.9 8.0 5 1 3 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 PVD35924.1 - 2.9e-12 46.4 52.4 0.21 12.3 0.0 18.3 21 0 0 21 21 17 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD35924.1 - 4.5e-11 42.7 36.0 5.8e-05 22.6 3.9 7.6 5 2 2 8 8 8 3 MalT-like TPR region TPR_21 PF09976.9 PVD35924.1 - 2.4e-08 33.9 38.7 0.0051 16.5 0.8 7.4 4 2 4 8 8 8 5 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 PVD35924.1 - 3.1e-08 33.5 11.6 26 5.8 0.0 10.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD35924.1 - 8.7e-08 31.8 34.8 0.1 12.5 0.2 12.1 14 0 0 14 14 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 PVD35924.1 - 3e-06 27.3 21.2 0.88 9.8 0.0 9.8 10 1 1 11 11 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD35924.1 - 3.1e-06 27.2 14.3 1.5 9.0 0.0 7.7 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 PVD35924.1 - 1.2e-05 24.9 21.5 0.2 11.0 0.0 8.3 7 4 3 10 10 10 2 Coatomer epsilon subunit SHNi-TPR PF10516.9 PVD35924.1 - 1.2e-05 24.7 5.8 0.037 13.5 0.1 4.9 6 0 0 6 6 5 1 SHNi-TPR TPR_20 PF14561.6 PVD35924.1 - 0.00031 21.0 34.2 0.88 9.9 1.5 10.8 7 2 4 12 12 12 1 Tetratricopeptide repeat ChAPs PF09295.10 PVD35924.1 - 0.00098 18.2 11.7 0.87 8.5 0.0 6.4 3 2 4 7 7 7 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 PVD35924.1 - 0.0014 17.6 29.2 0.57 9.0 0.1 7.9 5 3 2 7 7 7 2 NMDA receptor-regulated protein 1 HEPN PF05168.14 PVD35924.1 - 0.0086 16.2 3.4 6.4 6.9 0.1 4.3 3 0 0 3 3 3 0 HEPN domain SPOB_a PF14689.6 PVD35924.1 - 0.057 13.1 9.6 11 5.9 0.1 5.7 6 0 0 6 6 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR PF01535.20 PVD35924.1 - 0.12 12.7 21.5 3.3 8.2 0.0 10.6 13 0 0 13 13 9 0 PPR repeat SRP_TPR_like PF17004.5 PVD35924.1 - 0.16 12.0 24.6 0.4 10.7 1.8 6.3 5 0 0 5 5 5 0 Putative TPR-like repeat YfdX PF10938.8 PVD35924.1 - 0.33 10.9 20.1 0.5 10.3 1.6 6.6 4 2 1 5 5 5 0 YfdX protein Clathrin PF00637.20 PVD35924.1 - 1.6 8.6 27.2 0.37 10.7 2.5 6.9 6 2 3 9 9 6 0 Region in Clathrin and VPS RPN6_N PF18055.1 PVD35924.1 - 3.9 7.8 19.9 2 8.8 2.2 6.4 5 2 1 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain RPN7 PF10602.9 PVD35924.1 - 6.9 6.3 18.5 1.3 8.7 0.2 7.0 7 2 0 8 8 8 0 26S proteasome subunit RPN7 OmdA PF13376.6 PVD35925.1 - 0.0059 16.6 0.8 0.013 15.5 0.8 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated bZIP_2 PF07716.15 PVD35926.1 - 0.00037 20.5 6.8 0.0008 19.4 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Profilin PF00235.19 PVD35927.1 - 3.1e-24 85.6 0.2 3.5e-24 85.5 0.2 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 PVD35928.1 - 5.4e-09 36.4 0.0 6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Profilin Vps16_N PF04841.13 PVD35929.1 - 1.1e-120 403.2 0.1 1.4e-120 402.8 0.1 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 PVD35929.1 - 6.3e-96 321.2 3.1 6.3e-96 321.2 3.1 1.5 2 0 0 2 2 2 1 Vps16, C-terminal region MBD PF01429.19 PVD35930.1 - 0.0042 16.8 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyl-CpG binding domain tRNA-synt_2c PF01411.19 PVD35931.1 - 5.5e-07 28.5 0.0 8.1e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PVD35931.1 - 6.7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-C2H2 PF00096.26 PVD35932.1 - 7.7e-06 26.1 27.5 0.00081 19.7 0.3 5.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD35932.1 - 0.0012 19.5 5.9 0.0069 17.1 0.4 5.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD35932.1 - 0.014 15.7 4.5 3.1 8.2 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_6 PF18450.1 PVD35932.1 - 0.019 14.7 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Zinc Finger domain zinc_ribbon_10 PF10058.9 PVD35932.1 - 1.2 8.9 3.2 7.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NHL PF01436.21 PVD35933.1 - 2.4e-16 58.9 2.1 0.00015 21.7 0.0 5.0 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 PVD35933.1 - 2.2e-06 27.5 0.1 0.019 14.5 0.0 3.8 2 2 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PVD35933.1 - 2.6e-06 26.8 0.5 9.5e-05 21.7 0.7 2.7 2 1 0 2 2 2 1 6-bladed beta-propeller TruB_C PF09142.11 PVD35933.1 - 0.13 12.0 0.0 11 5.9 0.0 3.3 3 1 1 4 4 4 0 tRNA Pseudouridine synthase II, C terminal PHD PF00628.29 PVD35934.1 - 1.3e-20 73.0 26.1 8.3e-12 44.8 7.8 3.2 3 0 0 3 3 3 2 PHD-finger Bromodomain PF00439.25 PVD35934.1 - 6.8e-20 70.9 0.1 1.8e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 PVD35934.1 - 4.6e-16 58.3 0.1 1.7e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Methyl-CpG binding domain WSD PF15613.6 PVD35934.1 - 2.8e-13 50.2 0.6 7.5e-08 32.8 0.4 5.0 4 2 0 4 4 4 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 PVD35934.1 - 7.4e-08 32.6 0.9 1.7e-07 31.4 0.9 1.7 1 0 0 1 1 1 1 DDT domain PHD_2 PF13831.6 PVD35934.1 - 5e-05 22.8 9.7 0.0025 17.3 0.9 2.6 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 PVD35934.1 - 0.64 10.3 15.4 1.1 9.5 4.7 3.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 PVD35934.1 - 8.9 6.3 14.4 2.3 8.2 1.8 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cloacin PF03515.14 PVD35935.1 - 0.13 11.9 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain SNF2_N PF00176.23 PVD35938.1 - 8.2e-60 202.4 0.1 8.2e-60 202.4 0.1 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD35938.1 - 1.1e-19 70.8 1.6 2e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 PVD35938.1 - 5.1e-10 39.0 1.0 5.1e-10 39.0 1.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 PVD35938.1 - 5.7e-06 26.4 6.7 6.6e-05 23.0 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.21 PVD35939.1 - 2.5e-12 46.7 8.7 3.8e-12 46.1 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD35939.1 - 1.2e-09 38.1 8.4 1.9e-09 37.5 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD35939.1 - 6.2e-06 26.7 6.6 1.2e-05 25.7 6.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 PVD35939.1 - 0.024 15.1 2.8 0.046 14.2 2.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.5 PVD35939.1 - 0.043 13.9 2.1 0.13 12.4 2.1 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation GIT_CC PF16559.5 PVD35939.1 - 0.044 13.6 1.5 0.14 12.0 1.5 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 PVD35939.1 - 0.056 13.2 2.0 0.1 12.4 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Trp_leader2 PF08056.11 PVD35939.1 - 0.21 11.6 0.1 0.48 10.4 0.1 1.5 1 0 0 1 1 1 0 Tryptophan operon leader peptide HALZ PF02183.18 PVD35939.1 - 0.39 11.0 2.1 0.77 10.0 2.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper C1q PF00386.21 PVD35941.1 - 5.9e-24 84.7 0.0 7.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 PVD35941.1 - 1.6e-05 24.6 11.4 3e-05 23.7 11.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 PVD35941.1 - 0.0059 16.5 0.2 0.0088 15.9 0.2 1.2 1 0 0 1 1 1 1 BclA C-terminal domain FAM176 PF14851.6 PVD35941.1 - 0.038 13.7 0.1 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 FAM176 family PPC PF04151.15 PVD35941.1 - 0.041 15.0 0.3 0.076 14.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain LYRIC PF15686.5 PVD35941.1 - 0.15 11.6 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family EcoRI PF02963.16 PVD35942.1 - 0.00023 20.3 0.3 0.00036 19.6 0.3 1.2 1 0 0 1 1 1 1 Restriction endonuclease EcoRI EGF PF00008.27 PVD35942.1 - 0.027 14.8 8.4 0.027 14.8 8.4 3.3 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 PVD35944.1 - 0.0041 17.5 9.3 0.0041 17.5 9.3 2.2 2 0 0 2 2 2 1 EGF-like domain MHC2-interact PF09307.10 PVD35944.1 - 0.024 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 CLIP, MHC2 interacting SKICH PF17751.1 PVD35945.1 - 1.7e-21 76.7 0.5 4.5e-21 75.3 0.5 1.8 1 0 0 1 1 1 1 SKICH domain HMMR_C PF15908.5 PVD35945.1 - 2.4 8.4 10.3 0.034 14.4 2.2 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal ATAD4 PF15321.6 PVD35946.1 - 1.3e-05 26.5 1.2 1.3e-05 26.5 1.2 2.2 2 0 0 2 2 2 1 ATPase family AAA domain containing 4 SR-25 PF10500.9 PVD35946.1 - 0.057 13.0 17.7 0.069 12.7 17.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Polyoma_lg_T_C PF06431.11 PVD35946.1 - 0.38 9.6 1.7 0.4 9.5 1.7 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus RAP1 PF07218.11 PVD35946.1 - 4.4 5.5 7.5 4.4 5.5 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl-CoA_dh_1 PF00441.24 PVD35947.1 - 2.9e-40 137.9 0.1 4.2e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD35947.1 - 1.8e-26 93.0 0.0 3.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD35947.1 - 7.4e-23 80.6 0.0 1.3e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD35947.1 - 7.4e-13 48.9 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 PVD35947.1 - 0.038 13.6 0.0 0.092 12.4 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FA_hydroxylase PF04116.13 PVD35948.1 - 1.6e-26 93.2 14.2 1.6e-26 93.2 14.2 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ASC PF00858.24 PVD35949.1 - 7e-77 259.3 0.6 8.1e-77 259.0 0.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel BCDHK_Adom3 PF10436.9 PVD35950.1 - 8.3e-55 185.0 0.2 1.3e-54 184.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PVD35950.1 - 4.7e-12 46.4 0.0 8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PVD35950.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RapA_C PF12137.8 PVD35950.1 - 0.12 11.4 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal RNase_H_2 PF13482.6 PVD35951.1 - 0.0015 18.6 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 RNase_H superfamily CSRNP_N PF16019.5 PVD35952.1 - 0.058 13.3 0.2 0.08 12.8 0.2 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus KCNQ2_u3 PF16642.5 PVD35952.1 - 3.8 8.6 8.3 30 5.7 2.0 2.6 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DFP PF04127.15 PVD35953.1 - 2.6e-18 66.5 0.0 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Ank_2 PF12796.7 PVD35954.1 - 1e-58 195.9 21.3 2.4e-14 53.7 0.1 8.7 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD35954.1 - 1.2e-48 162.8 15.1 2.8e-09 37.3 0.0 12.7 5 5 9 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD35954.1 - 1.5e-39 133.5 17.8 7.7e-06 26.1 0.0 12.4 8 2 4 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD35954.1 - 8.1e-39 127.2 18.8 0.011 16.1 0.0 16.8 18 0 0 18 18 18 11 Ankyrin repeat Ank PF00023.30 PVD35954.1 - 9.4e-35 117.6 16.9 0.00055 20.3 0.0 15.2 15 0 0 15 15 15 8 Ankyrin repeat Ion_trans PF00520.31 PVD35954.1 - 7.2e-08 32.0 21.0 1.3e-07 31.1 21.0 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PVD35954.1 - 7.6e-05 21.6 15.2 0.00015 20.6 15.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel SHMT PF00464.19 PVD35955.1 - 2e-189 629.3 0.0 2.4e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ras PF00071.22 PVD35956.1 - 6.9e-44 149.3 0.3 8.3e-44 149.0 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD35956.1 - 1.8e-18 66.9 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD35956.1 - 2.1e-12 46.9 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD35956.1 - 9.6e-07 28.9 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD35956.1 - 3.4e-06 27.1 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PVD35956.1 - 3e-05 23.5 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD35956.1 - 3.4e-05 23.5 0.0 6.5e-05 22.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 PVD35956.1 - 3.8e-05 23.6 0.4 9.1e-05 22.4 0.2 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 PVD35956.1 - 0.00015 21.3 0.0 0.00043 19.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 PVD35956.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NEMP PF10225.9 PVD35957.1 - 2e-71 240.6 7.1 2.7e-71 240.2 7.1 1.2 1 0 0 1 1 1 1 NEMP family DUF2721 PF11026.8 PVD35957.1 - 1.1 9.1 6.4 0.6 10.0 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Homeobox_KN PF05920.11 PVD35959.1 - 4.5e-17 61.7 0.7 6.5e-17 61.1 0.7 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD35959.1 - 9.1e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain DUF4555 PF15093.6 PVD35960.1 - 3.5e-59 200.4 1.7 3.5e-59 200.4 1.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4555) RICTOR_phospho PF14665.6 PVD35960.1 - 0.39 11.1 7.6 0.37 11.1 2.0 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Acyl-CoA_dh_1 PF00441.24 PVD35962.1 - 4.3e-43 147.1 0.1 5.9e-43 146.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD35962.1 - 2.1e-31 108.9 0.0 5.1e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD35962.1 - 1.9e-26 92.1 0.0 3.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD35962.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 PVD35962.1 - 0.0056 17.2 0.1 0.017 15.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal MFS_1 PF07690.16 PVD35964.1 - 4.1e-14 52.3 19.4 2e-07 30.3 9.1 3.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PVD35964.1 - 7.8e-09 34.6 15.4 5.6e-07 28.5 0.3 3.7 4 0 0 4 4 4 2 MFS/sugar transport protein DUF3169 PF11368.8 PVD35964.1 - 0.028 13.9 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Laminin_II PF06009.12 PVD35967.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF2560 PF10834.8 PVD35969.1 - 0.18 12.0 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Peptidase_M8 PF01457.16 PVD35970.1 - 1e-50 172.9 11.1 2.8e-50 171.5 11.1 1.5 1 1 0 1 1 1 1 Leishmanolysin EF-hand_7 PF13499.6 PVD35971.1 - 2.8e-12 46.9 3.9 1.7e-06 28.4 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD35971.1 - 2.2e-07 30.2 0.3 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD35971.1 - 4.3e-05 22.8 1.1 0.075 12.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD35971.1 - 0.0065 16.3 3.7 0.055 13.3 0.1 3.1 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD35971.1 - 0.01 15.3 0.8 0.47 10.0 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF1493 PF07377.12 PVD35971.1 - 0.087 13.3 1.2 0.15 12.5 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) LSDAT_euk PF18139.1 PVD35972.1 - 7e-58 196.1 1.2 8.4e-57 192.6 0.2 2.3 1 1 1 2 2 2 2 SLOG in TRPM Ion_trans PF00520.31 PVD35972.1 - 3.8e-15 55.8 22.6 1.2e-14 54.1 22.6 1.9 1 1 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 PVD35972.1 - 2e-13 50.1 0.0 4.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote NHL PF01436.21 PVD35973.1 - 1.2e-15 56.7 1.4 0.00028 20.7 0.1 4.9 4 0 0 4 4 4 3 NHL repeat SGL PF08450.12 PVD35973.1 - 1.7e-08 34.4 0.0 0.0091 15.6 0.0 4.1 2 2 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PVD35973.1 - 4.2e-06 26.1 0.8 5.6e-05 22.5 0.6 2.4 2 1 0 2 2 2 1 6-bladed beta-propeller Homeodomain PF00046.29 PVD35974.1 - 2.8e-23 81.5 3.5 4.5e-23 80.9 3.5 1.3 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 PVD35974.1 - 2.1e-18 65.2 0.0 3.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 PVD35974.1 - 0.0026 17.6 0.7 0.0063 16.4 0.7 1.8 1 1 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 PVD35974.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2316 PF10078.9 PVD35974.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Sulfotransfer_2 PF03567.14 PVD35978.1 - 1e-41 143.5 1.7 1.5e-41 143.0 1.7 1.2 1 0 0 1 1 1 1 Sulfotransferase family FRB_dom PF08771.11 PVD35978.1 - 0.077 13.4 4.2 0.68 10.4 0.1 3.0 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Metallothio_Euk PF12749.7 PVD35979.1 - 2.9 8.1 17.4 6.3 7.0 17.4 1.9 1 1 0 1 1 1 0 Eukaryotic metallothionein SOG2 PF10428.9 PVD35979.1 - 5.2 6.2 31.3 6.3 5.9 31.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein EGF_2 PF07974.13 PVD35981.1 - 4.5e-11 42.9 84.0 0.00046 20.5 11.8 5.5 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 PVD35981.1 - 7.1e-05 23.3 59.8 0.015 15.9 8.2 6.4 5 0 0 5 5 5 4 Human growth factor-like EGF EGF PF00008.27 PVD35981.1 - 0.00012 22.3 72.0 0.00014 22.1 8.8 6.1 6 0 0 6 6 6 4 EGF-like domain Laminin_G_3 PF13385.6 PVD35981.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EB PF01683.18 PVD35981.1 - 3.7 7.9 60.3 0.12 12.7 2.5 5.7 2 1 1 3 3 3 0 EB module NtA PF03146.15 PVD35983.1 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Agrin NtA domain CLASP_N PF12348.8 PVD35984.1 - 1.1e-54 185.4 6.0 3e-37 128.4 0.9 4.3 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 PVD35984.1 - 1.3e-15 56.2 5.0 0.00036 20.5 0.0 8.1 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 PVD35984.1 - 9.9e-10 38.7 1.6 0.075 13.4 0.0 5.5 4 1 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 PVD35984.1 - 8e-09 36.0 0.8 1.2 9.7 0.0 6.5 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PVD35984.1 - 1.6e-06 28.2 7.5 0.47 10.5 0.0 7.3 6 2 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 PVD35984.1 - 2.5e-06 27.7 2.3 0.0006 20.0 0.0 4.2 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 PVD35984.1 - 6.9e-06 26.4 0.4 3.2 8.4 0.0 5.4 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 PVD35984.1 - 0.00015 21.9 2.5 0.0058 16.8 0.1 4.5 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 PVD35984.1 - 0.00029 20.5 1.8 1.2 8.6 0.0 5.3 6 0 0 6 6 6 1 Tti2 family Adaptin_N PF01602.20 PVD35984.1 - 0.001 17.7 4.4 1 7.9 0.1 4.3 5 0 0 5 5 5 2 Adaptin N terminal region Dopey_N PF04118.14 PVD35984.1 - 0.002 17.3 0.2 0.71 8.9 0.0 3.2 3 0 0 3 3 3 1 Dopey, N-terminal MMS19_N PF14500.6 PVD35984.1 - 0.0071 15.9 2.3 1.3 8.6 0.0 4.3 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II NUC173 PF08161.12 PVD35984.1 - 0.059 13.0 0.2 10 5.7 0.0 3.7 4 1 0 4 4 4 0 NUC173 domain NopRA1 PF16201.5 PVD35984.1 - 0.075 12.6 0.0 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Glycogen_syn PF05693.13 PVD35984.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen synthase Ipi1_N PF12333.8 PVD35984.1 - 0.37 11.4 0.1 0.37 11.4 0.1 4.0 4 0 0 4 4 3 0 Rix1 complex component involved in 60S ribosome maturation An_peroxidase PF03098.15 PVD35985.1 - 5.6e-126 421.2 0.0 4.2e-81 273.1 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase Peptidase_M24 PF00557.24 PVD35986.1 - 2.4e-23 82.9 0.2 3.6e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 HIM1 PF08732.10 PVD35986.1 - 0.038 13.5 0.1 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 HIM1 cwf18 PF08315.12 PVD35987.1 - 1.9e-33 116.0 11.5 2.4e-33 115.7 11.5 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF3461 PF11944.8 PVD35987.1 - 0.043 13.9 0.7 0.076 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) DELLA PF12041.8 PVD35987.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Spore_III_AB PF09548.10 PVD35987.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CUB PF00431.20 PVD35988.1 - 0 2384.5 22.2 1.6e-33 115.3 0.0 28.8 27 2 1 28 28 28 28 CUB domain EGF PF00008.27 PVD35988.1 - 1.1e-22 80.0 116.8 2.8e-08 33.9 9.4 9.8 9 0 0 9 9 8 6 EGF-like domain CUB_2 PF02408.20 PVD35988.1 - 9e-21 73.9 65.6 0.039 13.7 0.1 22.1 25 0 0 25 25 25 7 CUB-like domain EGF_CA PF07645.15 PVD35988.1 - 1.9e-17 63.1 120.1 9.5e-06 25.7 5.6 9.2 8 0 0 8 8 8 6 Calcium-binding EGF domain hEGF PF12661.7 PVD35988.1 - 2.4e-12 47.0 86.4 8.1e-05 23.1 7.8 9.0 8 1 0 8 8 6 5 Human growth factor-like EGF EGF_3 PF12947.7 PVD35988.1 - 3.5e-12 46.3 105.7 2.1e-08 34.2 8.7 9.7 8 0 0 8 8 8 5 EGF domain FXa_inhibition PF14670.6 PVD35988.1 - 5.7e-06 26.5 114.1 0.002 18.4 10.0 9.1 7 1 1 8 8 8 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD35988.1 - 0.00093 19.1 2.6 0.00093 19.1 2.6 9.1 8 0 0 8 8 8 4 Complement Clr-like EGF-like EGF_2 PF07974.13 PVD35988.1 - 0.0012 19.1 113.6 0.0082 16.5 12.4 8.5 7 1 1 8 8 6 5 EGF-like domain Lectin_N PF03954.14 PVD35988.1 - 0.3 10.8 1.1 0.62 9.8 1.1 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain HsbA PF12296.8 PVD35988.1 - 1.6 9.2 7.6 16 6.0 7.5 2.2 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 PVD35988.1 - 1.8 8.6 15.9 12 6.0 15.9 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 PVD35989.1 - 1e-46 155.9 37.0 2.7e-08 34.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD35989.1 - 1.9e-14 53.7 0.7 0.034 14.4 0.0 6.7 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD35989.1 - 7.2e-05 21.9 8.0 1.7 7.5 4.8 4.2 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD35989.1 - 0.0013 18.7 5.0 2 8.2 0.0 3.9 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PVD35989.1 - 0.0024 16.6 9.9 1.8 7.1 0.2 4.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 MCRS_N PF13325.6 PVD35989.1 - 0.0038 17.2 1.5 0.0038 17.2 1.5 1.7 1 1 0 1 1 1 1 N-terminal region of micro-spherule protein Cep57_CLD_2 PF14197.6 PVD35989.1 - 0.3 11.2 6.7 3.4 7.8 0.6 3.8 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 CorA PF01544.18 PVD35989.1 - 0.31 10.3 1.7 0.6 9.4 1.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein YabA PF06156.13 PVD35989.1 - 0.61 10.7 6.8 0.67 10.6 1.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 PVD35989.1 - 0.79 8.2 5.0 1.2 7.6 5.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 PVD35989.1 - 1.3 6.9 6.5 1.8 6.4 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4472 PF14739.6 PVD35989.1 - 4.5 8.1 9.8 3.6 8.4 5.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) HEXIM PF15313.6 PVD35990.1 - 1.7e-40 138.5 1.3 1.7e-40 138.5 1.3 2.2 3 0 0 3 3 3 1 Hexamethylene bis-acetamide-inducible protein MFMR_assoc PF16596.5 PVD35990.1 - 0.67 10.4 7.5 1.2 9.6 2.9 2.4 2 1 0 2 2 2 0 Disordered region downstream of MFMR TSGP1 PF07771.11 PVD35990.1 - 0.75 10.0 5.9 0.28 11.3 2.9 1.7 2 0 0 2 2 2 0 Tick salivary peptide group 1 Leu_zip PF15294.6 PVD35993.1 - 2.2e-103 345.6 20.2 2.4e-103 345.4 20.2 1.0 1 0 0 1 1 1 1 Leucine zipper Spc7 PF08317.11 PVD35993.1 - 0.049 12.5 17.7 0.22 10.4 10.7 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 PVD35993.1 - 0.22 10.8 20.1 0.75 9.1 0.7 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 PVD35993.1 - 0.75 10.0 8.3 0.35 11.1 4.2 2.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF5357 PF17310.2 PVD35993.1 - 3.9 5.9 4.4 8.4 4.8 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5357) Macoilin PF09726.9 PVD35993.1 - 8.1 4.9 20.3 0.44 9.1 14.5 1.6 1 1 1 2 2 2 0 Macoilin family RRM_1 PF00076.22 PVD35994.1 - 3.4e-14 52.4 0.1 5.7e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5423 PF17461.2 PVD35994.1 - 7.3 5.3 7.6 12 4.6 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Costars PF14705.6 PVD35995.1 - 1.1e-27 96.0 0.1 1.2e-27 95.9 0.1 1.0 1 0 0 1 1 1 1 Costars Anti-adapt_IraP PF10796.9 PVD35995.1 - 0.11 13.1 0.0 1.2 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Glyco_transf_92 PF01697.27 PVD35996.1 - 0.00086 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 PVD35997.1 - 7.1e-19 68.5 0.8 3.1e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD35997.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 TAP42 PF04177.12 PVD35998.1 - 7e-80 268.5 11.5 8.5e-80 268.3 11.5 1.0 1 0 0 1 1 1 1 TAP42-like family Metallophos PF00149.28 PVD35999.1 - 2.6e-06 28.1 0.7 4.2e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 PVD35999.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily START PF01852.19 PVD36000.1 - 5.2e-15 55.4 1.4 7.8e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 START domain SEA PF01390.20 PVD36001.1 - 2.5e-08 34.0 0.0 2.5e-08 34.0 0.0 3.7 3 0 0 3 3 3 1 SEA domain DUF4448 PF14610.6 PVD36001.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 PVD36001.1 - 0.15 11.5 3.5 0.38 10.2 3.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HlyIII PF03006.20 PVD36003.1 - 5.8e-47 160.3 14.9 1.1e-46 159.4 14.9 1.4 1 0 0 1 1 1 1 Haemolysin-III related DUF4077 PF13295.6 PVD36003.1 - 0.013 15.4 0.6 0.013 15.4 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4077) MOLO1 PF17175.4 PVD36005.1 - 0.021 14.9 0.1 0.034 14.3 0.1 1.4 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 Ldl_recept_b PF00058.17 PVD36006.1 - 2.9e-32 110.9 7.5 4.6e-05 23.8 0.0 7.4 7 2 0 7 7 7 5 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 PVD36006.1 - 2.9e-05 23.5 0.0 0.22 10.7 0.0 3.1 3 1 1 4 4 4 2 Domain of unknown function (DUF5050) SGL PF08450.12 PVD36006.1 - 0.00018 21.2 0.0 0.091 12.3 0.0 2.9 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Syndecan PF01034.20 PVD36006.1 - 0.011 15.6 0.9 0.022 14.7 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM132D_C PF15706.5 PVD36006.1 - 0.036 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term cEGF PF12662.7 PVD36007.1 - 7.5e-62 204.8 181.2 4.4e-09 36.1 0.7 20.6 20 0 0 20 20 20 15 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD36007.1 - 1.8e-61 204.1 325.8 5.9e-08 32.8 5.5 20.5 17 3 3 20 20 20 14 Calcium-binding EGF domain CUB PF00431.20 PVD36007.1 - 7.6e-52 174.3 5.8 1e-18 67.7 0.0 5.7 4 1 0 4 4 4 4 CUB domain FXa_inhibition PF14670.6 PVD36007.1 - 3.3e-41 139.3 307.6 1.2e-06 28.6 8.9 20.3 15 2 5 20 20 20 14 Coagulation Factor Xa inhibitory site SRCR PF00530.18 PVD36007.1 - 1.6e-36 124.8 6.5 3.4e-14 53.2 0.3 9.1 8 3 2 10 10 10 3 Scavenger receptor cysteine-rich domain NIDO PF06119.14 PVD36007.1 - 1.4e-09 38.7 2.6 4e-09 37.3 2.6 1.9 1 0 0 1 1 1 1 Nidogen-like hEGF PF12661.7 PVD36007.1 - 0.013 16.1 1.0 0.013 16.1 1.0 22.2 20 2 2 22 22 22 0 Human growth factor-like EGF EGF_CA PF07645.15 PVD36008.1 - 3.1e-79 261.0 329.3 3.4e-10 40.0 9.7 21.2 20 1 1 21 21 21 14 Calcium-binding EGF domain cEGF PF12662.7 PVD36008.1 - 2.1e-75 248.1 206.0 5e-08 32.7 3.6 21.5 20 0 0 20 20 20 17 Complement Clr-like EGF-like CUB PF00431.20 PVD36008.1 - 4e-74 246.0 9.0 1.3e-18 67.3 0.0 5.6 5 0 0 5 5 5 5 CUB domain FXa_inhibition PF14670.6 PVD36008.1 - 9.3e-48 160.2 343.5 2e-07 31.2 8.2 21.6 18 1 3 21 21 21 17 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 PVD36008.1 - 4.6e-05 23.5 18.5 0.00037 20.6 4.4 22.3 20 4 0 21 21 21 13 EGF domain hEGF PF12661.7 PVD36008.1 - 0.0021 18.6 5.9 0.0021 18.6 5.9 22.4 22 1 0 22 22 22 10 Human growth factor-like EGF EGF PF00008.27 PVD36008.1 - 0.008 16.5 0.7 0.008 16.5 0.7 22.5 22 1 0 22 22 22 9 EGF-like domain HmuY PF14064.6 PVD36008.1 - 0.015 15.5 0.0 0.067 13.4 0.0 2.1 1 1 0 1 1 1 0 HmuY protein NIDO PF06119.14 PVD36008.1 - 0.022 15.7 0.1 0.11 13.5 0.0 2.3 2 0 0 2 2 2 0 Nidogen-like RPS31 PF17067.5 PVD36008.1 - 4.6 7.5 8.0 10 6.4 2.2 3.8 3 0 0 3 3 3 0 Ribosomal protein S31e CUB PF00431.20 PVD36009.1 - 5.3e-58 194.1 2.7 1.4e-20 73.7 0.0 4.5 4 0 0 4 4 4 4 CUB domain SRCR PF00530.18 PVD36009.1 - 4.3e-26 91.3 0.0 9.5e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain NIDO PF06119.14 PVD36009.1 - 1.5e-10 41.9 3.2 6.7e-10 39.8 3.2 2.3 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 PVD36009.1 - 5.1e-07 30.1 0.2 2.2e-06 28.0 0.1 2.3 2 1 0 2 2 2 1 von Willebrand factor type D domain CUB_2 PF02408.20 PVD36009.1 - 0.00016 21.4 1.0 0.018 14.8 0.2 3.6 3 0 0 3 3 3 1 CUB-like domain AMOP PF03782.17 PVD36009.1 - 0.062 13.4 8.5 0.31 11.1 8.5 2.2 1 1 0 1 1 1 0 AMOP domain EGF_CA PF07645.15 PVD36010.1 - 3.7e-133 433.5 650.0 6.2e-09 35.9 7.8 38.5 35 4 4 39 39 39 26 Calcium-binding EGF domain cEGF PF12662.7 PVD36010.1 - 1.3e-122 399.1 386.5 8.9e-08 31.9 2.0 39.0 38 0 0 38 38 38 32 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36010.1 - 4.9e-58 193.1 631.2 2.8e-07 30.7 8.2 39.1 30 6 9 39 39 39 27 Coagulation Factor Xa inhibitory site NIDO PF06119.14 PVD36010.1 - 4.4e-15 56.4 3.7 9.3e-08 32.9 1.1 3.3 3 0 0 3 3 3 2 Nidogen-like SEA PF01390.20 PVD36010.1 - 0.00017 21.7 1.3 0.00057 20.0 1.3 2.0 1 0 0 1 1 1 1 SEA domain EGF_3 PF12947.7 PVD36010.1 - 0.00056 20.0 15.5 0.00083 19.5 2.6 40.4 38 4 1 40 40 40 22 EGF domain EGF PF00008.27 PVD36010.1 - 0.01 16.1 0.4 0.01 16.1 0.4 41.0 39 1 0 39 39 39 0 EGF-like domain PRIMA1 PF16101.5 PVD36010.1 - 0.056 13.5 4.1 0.47 10.5 0.2 3.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Cupredoxin_1 PF13473.6 PVD36010.1 - 0.086 13.0 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 Cupredoxin-like domain Cadherin PF00028.17 PVD36010.1 - 0.12 12.8 4.8 5.9 7.4 0.7 3.3 4 0 0 4 4 4 0 Cadherin domain CUB PF00431.20 PVD36011.1 - 4.7e-77 255.4 8.3 9.6e-19 67.8 0.0 5.3 5 0 0 5 5 5 5 CUB domain SRCR PF00530.18 PVD36011.1 - 6.9e-12 45.7 0.0 1.8e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain HmuY PF14064.6 PVD36011.1 - 0.00043 20.5 0.0 0.0026 18.0 0.0 2.3 1 1 0 1 1 1 1 HmuY protein EGF_CA PF07645.15 PVD36012.1 - 2e-44 149.5 163.7 1.2e-10 41.4 9.7 11.5 10 1 1 11 11 11 7 Calcium-binding EGF domain cEGF PF12662.7 PVD36012.1 - 9.1e-31 105.4 110.6 2.3e-08 33.8 2.0 11.8 12 0 0 12 12 12 10 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36012.1 - 1.4e-21 76.4 169.4 4.7e-06 26.8 11.4 12.0 12 0 0 12 12 12 9 Coagulation Factor Xa inhibitory site VWD PF00094.25 PVD36012.1 - 2.5e-15 57.1 0.5 2.2e-14 54.1 0.1 2.6 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_3 PF12947.7 PVD36012.1 - 7.3e-06 26.1 138.1 0.00035 20.7 6.2 12.0 10 3 1 11 11 11 7 EGF domain EGF PF00008.27 PVD36012.1 - 5.8e-05 23.3 140.5 0.0045 17.2 7.1 12.8 11 3 1 12 12 12 7 EGF-like domain hEGF PF12661.7 PVD36012.1 - 0.027 15.1 2.9 0.027 15.1 2.9 13.6 13 2 0 13 13 13 0 Human growth factor-like EGF CUB PF00431.20 PVD36013.1 - 5.4e-77 255.2 5.3 1.6e-18 67.1 0.0 5.3 5 0 0 5 5 5 5 CUB domain SRCR PF00530.18 PVD36013.1 - 3.5e-12 46.7 0.0 8.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain NIDO PF06119.14 PVD36013.1 - 5.4e-10 40.1 1.2 2.3e-09 38.1 1.2 2.2 1 0 0 1 1 1 1 Nidogen-like HmuY PF14064.6 PVD36013.1 - 0.00012 22.3 0.0 0.00071 19.8 0.0 2.3 1 1 0 1 1 1 1 HmuY protein CRF-BP PF05428.11 PVD36013.1 - 0.0072 15.1 0.1 0.067 12.0 0.2 2.4 2 1 0 2 2 2 1 Corticotropin-releasing factor binding protein (CRF-BP) SusE PF14292.6 PVD36013.1 - 0.13 12.5 1.0 0.58 10.4 1.0 2.1 1 0 0 1 1 1 0 SusE outer membrane protein EGF_CA PF07645.15 PVD36014.1 - 8.3e-64 211.5 228.3 8.9e-10 38.6 11.3 14.5 14 1 0 14 14 14 10 Calcium-binding EGF domain CUB PF00431.20 PVD36014.1 - 1.1e-63 212.4 6.1 1.9e-14 53.9 0.1 5.6 4 1 1 5 5 5 5 CUB domain cEGF PF12662.7 PVD36014.1 - 5.4e-46 154.1 140.3 8.5e-09 35.2 3.2 16.0 15 0 0 15 15 15 12 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36014.1 - 6e-33 112.8 236.6 1.1e-06 28.8 9.8 16.2 14 1 2 16 16 16 11 Coagulation Factor Xa inhibitory site SRCR PF00530.18 PVD36014.1 - 2.7e-19 69.5 0.0 1.6e-15 57.4 0.0 5.2 4 1 0 4 4 4 2 Scavenger receptor cysteine-rich domain NIDO PF06119.14 PVD36014.1 - 2.3e-08 34.9 1.5 8e-08 33.1 1.5 2.1 1 0 0 1 1 1 1 Nidogen-like EGF PF00008.27 PVD36014.1 - 1.1e-05 25.6 198.2 0.00052 20.3 5.6 16.3 15 0 0 15 15 15 9 EGF-like domain EGF_3 PF12947.7 PVD36014.1 - 1.7e-05 24.9 195.7 0.0015 18.7 6.2 15.9 13 2 1 14 14 14 9 EGF domain Podoplanin PF05808.11 PVD36014.1 - 1.2 9.2 17.8 4 7.5 17.8 1.9 1 0 0 1 1 1 0 Podoplanin EGF_CA PF07645.15 PVD36015.1 - 1.8e-09 37.6 6.3 1.8e-09 37.6 6.3 3.1 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 PVD36015.1 - 0.022 15.1 3.0 0.022 15.1 3.0 3.6 3 1 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 PVD36015.1 - 0.034 14.4 7.1 0.034 14.4 7.1 4.1 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD36015.1 - 0.036 14.0 0.3 0.036 14.0 0.3 4.4 5 0 0 5 5 5 0 Complement Clr-like EGF-like TMP_2 PF06791.13 PVD36015.1 - 0.24 11.1 10.9 0.36 10.5 10.9 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein CUB PF00431.20 PVD36016.1 - 1.4e-87 289.4 8.2 7.3e-19 68.1 0.0 6.5 6 0 0 6 6 6 6 CUB domain EGF_CA PF07645.15 PVD36016.1 - 3.5e-32 110.3 128.8 1.6e-09 37.8 7.3 8.9 8 2 0 8 8 8 5 Calcium-binding EGF domain cEGF PF12662.7 PVD36016.1 - 1.4e-26 92.1 78.9 4.8e-08 32.8 4.1 10.1 10 0 0 10 10 10 7 Complement Clr-like EGF-like SRCR PF00530.18 PVD36016.1 - 6.6e-22 77.9 1.4 4.4e-11 43.2 0.0 4.5 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain FXa_inhibition PF14670.6 PVD36016.1 - 1.3e-20 73.3 134.3 4.8e-07 30.0 8.6 9.6 9 0 0 9 9 9 7 Coagulation Factor Xa inhibitory site VWD PF00094.25 PVD36016.1 - 7.7e-10 39.3 1.1 2.4e-09 37.7 0.2 2.4 2 0 0 2 2 2 1 von Willebrand factor type D domain NIDO PF06119.14 PVD36016.1 - 2.4e-07 31.6 1.4 9.1e-07 29.7 1.4 2.1 1 0 0 1 1 1 1 Nidogen-like EGF_3 PF12947.7 PVD36016.1 - 0.0045 17.2 5.8 0.0045 17.2 5.8 9.4 8 1 0 8 8 8 5 EGF domain CUB_2 PF02408.20 PVD36016.1 - 0.0063 16.3 1.9 0.84 9.4 0.1 4.3 3 0 0 3 3 3 1 CUB-like domain EGF PF00008.27 PVD36016.1 - 0.18 12.1 111.0 0.011 16.0 6.0 10.0 9 0 0 9 9 9 0 EGF-like domain CUB PF00431.20 PVD36017.1 - 1.9e-303 984.2 43.4 7.8e-19 68.0 0.0 24.5 22 3 3 25 25 25 23 CUB domain EGF_CA PF07645.15 PVD36017.1 - 4.8e-140 455.6 642.0 2e-09 37.5 9.2 39.6 36 4 4 40 40 40 26 Calcium-binding EGF domain SRCR PF00530.18 PVD36017.1 - 3.3e-104 342.0 73.8 1.9e-17 63.6 0.0 13.3 12 1 0 12 12 12 9 Scavenger receptor cysteine-rich domain cEGF PF12662.7 PVD36017.1 - 3.6e-93 304.9 417.0 1.2e-08 34.8 3.2 41.6 42 1 1 43 43 43 31 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36017.1 - 5.6e-57 189.7 626.4 1.3e-06 28.6 6.6 41.1 35 4 5 40 40 40 27 Coagulation Factor Xa inhibitory site NIDO PF06119.14 PVD36017.1 - 1e-18 68.0 8.3 4.8e-09 37.0 0.6 3.1 2 0 0 2 2 2 2 Nidogen-like EGF_3 PF12947.7 PVD36017.1 - 0.00092 19.4 4.2 0.00092 19.4 4.2 38.1 38 1 1 39 39 39 22 EGF domain DUF4251 PF14059.6 PVD36017.1 - 0.063 13.2 3.4 14 5.6 0.0 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4251) CUB PF00431.20 PVD36018.1 - 1.3e-77 257.2 12.2 1.5e-18 67.2 0.0 6.2 6 0 0 6 6 6 5 CUB domain cEGF PF12662.7 PVD36018.1 - 1.9e-58 194.0 162.3 8.8e-09 35.1 3.2 18.2 17 0 0 17 17 17 14 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD36018.1 - 2.7e-56 187.5 273.6 1.1e-09 38.3 8.5 17.6 17 1 0 17 17 17 10 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD36018.1 - 4.2e-33 113.3 274.8 4.7e-09 36.4 10.0 18.4 16 2 3 19 19 19 12 Coagulation Factor Xa inhibitory site SRCR PF00530.18 PVD36018.1 - 3.2e-29 101.4 13.1 5e-17 62.2 0.1 4.6 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain VWD PF00094.25 PVD36018.1 - 1.6e-16 61.0 1.5 4.6e-15 56.2 0.0 3.3 3 0 0 3 3 3 1 von Willebrand factor type D domain NIDO PF06119.14 PVD36018.1 - 3.8e-10 40.6 0.6 1.5e-09 38.7 0.6 2.1 1 0 0 1 1 1 1 Nidogen-like EGF_3 PF12947.7 PVD36018.1 - 0.001 19.2 4.6 0.001 19.2 4.6 18.1 15 2 1 16 16 16 9 EGF domain EGF PF00008.27 PVD36018.1 - 0.74 10.2 212.4 0.012 15.9 6.5 18.3 17 0 0 17 17 17 0 EGF-like domain Ldl_recept_b PF00058.17 PVD36019.1 - 3e-12 46.8 6.6 1.1e-05 25.8 0.1 4.7 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B CUB PF00431.20 PVD36019.1 - 8e-08 32.6 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain DUF5050 PF16472.5 PVD36019.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) SGL PF08450.12 PVD36019.1 - 0.051 13.1 0.0 1.7 8.1 0.0 2.5 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region zf-C2H2_11 PF16622.5 PVD36019.1 - 0.18 11.6 1.8 0.4 10.5 1.8 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type Homeodomain PF00046.29 PVD36020.1 - 1.2e-21 76.3 6.1 2e-21 75.6 6.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD36020.1 - 0.018 15.0 0.2 0.038 13.9 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Adeno_E3_CR2 PF02439.15 PVD36021.1 - 0.0016 18.1 0.3 0.0042 16.8 0.3 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1573 PF07610.11 PVD36021.1 - 0.04 13.9 1.4 0.34 11.0 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1573) CARDB PF07705.11 PVD36021.1 - 0.091 13.0 1.9 0.59 10.4 1.1 2.4 2 0 0 2 2 2 0 CARDB DUF2207 PF09972.9 PVD36021.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixG_C PF11614.8 PVD36021.1 - 0.19 12.0 0.5 0.6 10.3 0.2 1.9 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase YEATS PF03366.16 PVD36023.1 - 1.3e-24 85.9 0.2 3e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 YEATS family EGF_2 PF07974.13 PVD36024.1 - 0.086 13.2 27.7 1.4 9.4 10.2 2.8 2 0 0 2 2 2 0 EGF-like domain DUF1654 PF07867.11 PVD36025.1 - 5.4e-07 29.2 0.0 7 6.5 0.0 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF1654) Chorion_1 PF01723.16 PVD36025.1 - 0.0048 16.9 9.5 7.2 6.6 0.1 4.3 4 0 0 4 4 4 2 Chorion protein DUF753 PF05444.12 PVD36025.1 - 0.055 13.5 87.0 0.24 11.4 1.2 6.2 2 1 4 6 6 6 0 Protein of unknown function (DUF753) DapB_N PF01113.20 PVD36025.1 - 0.15 12.2 1.7 11 6.1 0.1 3.5 4 0 0 4 4 4 0 Dihydrodipicolinate reductase, N-terminus SAE2 PF08573.10 PVD36025.1 - 1.2 10.2 29.6 9.8 7.3 1.9 5.6 5 0 0 5 5 5 0 DNA repair protein endonuclease SAE2/CtIP C-terminus ALAD PF00490.21 PVD36025.1 - 9.6 5.3 7.4 29 3.7 0.2 3.0 3 0 0 3 3 3 0 Delta-aminolevulinic acid dehydratase Kinesin PF00225.23 PVD36027.1 - 5e-95 318.2 1.8 8.9e-95 317.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD36027.1 - 1.5e-16 60.7 0.0 1.5e-16 60.7 0.0 3.1 4 0 0 4 4 4 1 Microtubule binding FHA PF00498.26 PVD36027.1 - 5.8e-07 29.8 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PVD36027.1 - 2.3e-06 27.8 0.0 5.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 PVD36027.1 - 7e-05 23.2 1.1 7e-05 23.2 1.1 3.3 4 1 0 4 4 4 1 Kinesin protein 1B Kinesin_assoc PF16183.5 PVD36027.1 - 0.00012 22.3 5.0 0.00012 22.3 5.0 4.5 3 1 1 4 4 4 1 Kinesin-associated PTH2 PF01981.16 PVD36027.1 - 0.068 13.5 0.8 0.27 11.5 0.8 2.0 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 CX9C PF16860.5 PVD36028.1 - 3.6e-06 26.9 12.8 0.004 17.1 3.7 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 PVD36028.1 - 0.00031 20.8 16.0 0.0076 16.4 6.1 2.3 2 0 0 2 2 2 2 CHCH domain COX6B PF02297.17 PVD36028.1 - 0.0088 16.3 5.0 0.0088 16.3 5.0 2.5 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 PVD36028.1 - 2 8.5 14.3 1.5 8.9 4.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 PVD36028.1 - 3.4 8.0 11.5 1 9.7 5.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 MIP-T3 PF10243.9 PVD36029.1 - 3.2e-46 156.0 0.6 8.2e-46 154.6 0.6 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 PVD36029.1 - 6.3e-44 149.7 11.3 6.3e-44 149.7 11.3 3.2 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region DUF4880 PF16220.5 PVD36029.1 - 0.034 14.0 0.9 0.1 12.5 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) UAA PF08449.11 PVD36030.1 - 8.5e-61 205.8 13.9 1e-60 205.5 13.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PVD36030.1 - 4.1e-13 49.7 16.2 3.7e-06 27.1 1.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PVD36030.1 - 8.4e-11 41.8 6.7 9.2e-06 25.2 0.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family SLC35F PF06027.12 PVD36030.1 - 0.0013 18.4 8.6 0.0016 18.0 8.6 1.2 1 0 0 1 1 1 1 Solute carrier family 35 TMEM234 PF10639.9 PVD36030.1 - 0.021 14.9 5.9 0.13 12.3 2.6 3.0 3 0 0 3 3 3 0 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 PVD36030.1 - 0.031 13.4 3.8 0.6 9.2 2.6 2.6 1 1 0 2 2 2 0 Nucleotide-sugar transporter EmrE PF13536.6 PVD36030.1 - 0.067 12.8 9.5 0.18 11.4 0.1 3.3 2 2 1 4 4 4 0 Putative multidrug resistance efflux transporter Peptidase_Mx PF15887.5 PVD36030.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Sclerostin PF05463.11 PVD36032.1 - 2.1e-06 27.6 9.3 2.1e-06 27.6 9.3 1.6 1 1 1 2 2 2 1 Sclerostin (SOST) DAN PF03045.15 PVD36032.1 - 0.0026 17.8 2.0 0.0049 16.9 2.0 1.5 1 0 0 1 1 1 1 DAN domain DUF4820 PF16091.5 PVD36032.1 - 0.32 10.3 3.1 0.42 9.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Eapp_C PF10238.9 PVD36032.1 - 2.9 8.0 9.9 5 7.2 9.9 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein 7tm_1 PF00001.21 PVD36034.1 - 8e-09 35.2 22.1 7.4e-06 25.5 22.1 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2227 PF09988.9 PVD36034.1 - 0.59 10.0 3.6 13 5.6 0.2 2.8 1 1 1 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Death PF00531.22 PVD36035.1 - 5.4e-08 32.9 0.4 1.1e-07 31.8 0.4 1.6 1 0 0 1 1 1 1 Death domain ubiquitin PF00240.23 PVD36035.1 - 1e-06 28.4 1.6 0.0028 17.4 0.0 5.1 5 0 0 5 5 5 1 Ubiquitin family Ubiquitin_5 PF18037.1 PVD36035.1 - 0.013 15.8 2.0 1 9.7 1.0 3.3 2 1 1 3 3 3 0 Ubiquitin-like domain Death PF00531.22 PVD36036.1 - 1.8e-10 40.8 0.0 3.6e-10 39.8 0.0 1.4 2 0 0 2 2 2 1 Death domain LEP503 PF15221.6 PVD36036.1 - 0.15 12.4 0.5 0.58 10.5 0.1 2.1 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Prd1-P2 PF09214.11 PVD36038.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 LRR_6 PF13516.6 PVD36039.1 - 1.8e-21 74.3 0.2 0.00058 19.7 0.0 8.2 8 0 0 8 8 8 5 Leucine Rich repeat F-box-like PF12937.7 PVD36039.1 - 1.7e-13 50.2 4.0 4.6e-13 48.8 4.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD36039.1 - 1.6e-11 43.8 4.5 1.6e-11 43.8 4.5 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 PVD36039.1 - 1e-08 35.3 0.0 0.2 12.1 0.0 4.7 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD36039.1 - 0.014 15.9 6.7 1e+02 4.1 0.0 6.6 7 1 0 7 7 7 0 Leucine Rich Repeat Zn-C2H2_12 PF18112.1 PVD36040.1 - 4.3e-12 46.3 15.8 3.2e-08 33.9 3.8 2.5 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 PVD36040.1 - 8.3e-06 25.5 0.5 0.046 13.6 0.0 3.1 2 0 0 2 2 2 2 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 PVD36040.1 - 0.0027 17.6 4.6 0.017 15.0 0.2 2.7 2 0 0 2 2 2 1 Ubiquitin-binding zinc-finger zf-Di19 PF05605.12 PVD36040.1 - 0.0077 16.5 3.8 4.1 7.8 3.8 2.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 PVD36040.1 - 0.011 15.6 0.3 4.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.6 PVD36040.1 - 0.028 15.2 6.1 2.3 9.3 0.3 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 PVD36040.1 - 0.03 13.9 0.0 0.44 10.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_9 PF16293.5 PVD36040.1 - 0.063 13.1 0.6 13 5.7 0.0 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-ribbon_3 PF13248.6 PVD36040.1 - 0.076 12.4 1.0 9.5 5.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 PVD36040.1 - 0.095 13.0 0.6 23 5.3 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon DUF2256 PF10013.9 PVD36040.1 - 0.099 12.8 0.7 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 PVD36040.1 - 0.63 10.4 8.4 8.6 6.8 2.7 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Hrs_helical PF12210.8 PVD36040.1 - 0.75 10.4 8.6 0.63 10.6 5.9 2.2 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GED PF02212.18 PVD36040.1 - 1.4 9.1 9.6 0.24 11.6 3.4 2.5 2 0 0 2 2 2 0 Dynamin GTPase effector domain zf-C2H2 PF00096.26 PVD36040.1 - 2.7 8.6 5.3 23 5.7 0.2 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type V_ATPase_I PF01496.19 PVD36040.1 - 4.9 4.9 10.8 2.7 5.8 8.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 PVD36040.1 - 5.4 6.3 17.5 47 3.2 17.7 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_1 PF00515.28 PVD36041.1 - 5.1e-20 70.4 2.3 3.2e-06 26.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD36041.1 - 7.2e-16 57.0 1.1 1.2e-05 25.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD36041.1 - 1.7e-09 37.1 0.8 0.00021 21.2 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PVD36041.1 - 1.9e-09 37.0 0.9 0.00013 21.5 0.0 2.7 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 PVD36041.1 - 1.1e-06 28.8 4.4 0.017 15.4 0.1 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD36041.1 - 1.1e-06 28.9 0.2 0.0016 19.1 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD36041.1 - 2.6e-06 27.8 0.4 0.13 12.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PVD36041.1 - 8.5e-06 26.3 0.3 0.23 12.1 0.0 3.2 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD36041.1 - 1.5e-05 25.1 0.0 0.007 16.5 0.0 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD36041.1 - 4.1e-05 23.3 0.2 0.62 10.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD36041.1 - 0.00015 21.9 3.3 0.0079 16.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD36041.1 - 0.00015 22.2 0.3 0.0035 17.9 0.1 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Arm PF00514.23 PVD36041.1 - 0.00031 20.7 9.8 0.0022 18.0 0.1 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat NopRA1 PF16201.5 PVD36041.1 - 0.00051 19.7 0.1 0.0021 17.7 0.1 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 ANAPC3 PF12895.7 PVD36041.1 - 0.0011 19.1 4.1 0.0012 19.0 2.2 2.1 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4704 PF15787.5 PVD36041.1 - 0.0052 16.1 0.5 0.0052 16.1 0.5 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) BTAD PF03704.17 PVD36041.1 - 0.0052 17.2 1.3 0.036 14.5 1.3 2.5 1 1 0 1 1 1 1 Bacterial transcriptional activator domain RIH_assoc PF08454.11 PVD36041.1 - 0.0064 16.3 0.0 0.14 12.0 0.0 3.0 2 1 0 2 2 2 1 RyR and IP3R Homology associated RasGAP_C PF03836.15 PVD36041.1 - 0.012 15.7 1.8 0.035 14.2 1.8 1.8 1 0 0 1 1 1 0 RasGAP C-terminus TPR_10 PF13374.6 PVD36041.1 - 0.014 15.2 1.6 0.77 9.7 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat HMG_CoA_synt_C PF08540.10 PVD36041.1 - 0.029 14.0 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal HEAT_EZ PF13513.6 PVD36041.1 - 0.068 13.7 1.5 6.4 7.4 0.5 3.9 3 1 1 4 4 3 0 HEAT-like repeat Cnd1 PF12717.7 PVD36041.1 - 0.094 12.8 1.7 0.28 11.2 0.1 2.7 3 0 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 Fis1_TPR_C PF14853.6 PVD36041.1 - 0.13 12.3 0.6 9.6 6.4 0.0 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 PVD36041.1 - 0.41 10.7 5.0 2.4 8.3 0.1 4.0 2 1 2 4 4 3 0 MIT (microtubule interacting and transport) domain Atx10homo_assoc PF09759.9 PVD36041.1 - 0.6 10.2 5.3 0.98 9.5 0.1 3.9 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain IFT57 PF10498.9 PVD36042.1 - 6.2e-132 439.9 13.9 3.1e-84 283.0 0.2 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Spc7 PF08317.11 PVD36042.1 - 2.8e-05 23.2 12.2 4.6e-05 22.4 12.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.12 PVD36042.1 - 8.2e-05 22.6 4.3 0.00023 21.2 4.3 1.7 1 0 0 1 1 1 1 Laminin Domain II EzrA PF06160.12 PVD36042.1 - 0.0053 15.0 10.2 0.0092 14.2 9.7 1.6 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA PEPcase PF00311.17 PVD36042.1 - 0.046 11.8 6.7 0.061 11.4 6.7 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase GAS PF13851.6 PVD36042.1 - 0.06 12.7 11.4 0.15 11.4 11.4 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 PVD36042.1 - 0.16 12.1 9.0 0.46 10.6 9.0 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad1 PF08649.10 PVD36042.1 - 0.21 11.8 4.8 1.6 9.0 0.6 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 ZapD PF07072.11 PVD36042.1 - 0.27 10.9 9.0 1 9.1 0.8 2.3 2 0 0 2 2 2 0 Cell division protein CENP-H PF05837.12 PVD36042.1 - 0.34 11.3 10.0 0.2 12.0 7.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YgaB PF14182.6 PVD36042.1 - 0.46 10.9 6.5 9.4 6.7 1.6 2.8 2 0 0 2 2 2 0 YgaB-like protein Cep57_MT_bd PF06657.13 PVD36042.1 - 0.78 10.2 12.0 0.73 10.3 4.7 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF948 PF06103.11 PVD36042.1 - 1 9.7 4.7 1.8 8.9 1.1 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 PVD36042.1 - 1.1 7.8 10.6 2.6 6.5 10.5 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 PVD36042.1 - 1.3 8.0 13.2 2.3 7.3 13.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 PVD36042.1 - 1.4 9.3 15.2 20 5.6 14.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Fibin PF15819.5 PVD36042.1 - 1.6 8.5 6.7 0.74 9.5 2.6 2.2 1 1 0 2 2 2 0 Fin bud initiation factor homologue DUF1664 PF07889.12 PVD36042.1 - 1.7 8.7 8.1 0.77 9.8 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD36042.1 - 2.1 8.4 17.1 7.4 6.6 14.0 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 PVD36042.1 - 3.2 8.1 13.4 3.9 7.9 7.6 3.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 PVD36042.1 - 5.9 4.7 8.7 0.67 7.8 3.1 1.8 1 1 0 1 1 1 0 Prominin Occludin_ELL PF07303.13 PVD36042.1 - 6.5 7.5 9.0 2 9.2 2.7 2.9 3 0 0 3 3 3 0 Occludin homology domain TMPIT PF07851.13 PVD36042.1 - 8.3 5.6 8.5 0.96 8.6 3.2 1.6 1 1 2 3 3 3 0 TMPIT-like protein RUN PF02759.19 PVD36043.1 - 9.2e-09 35.4 3.3 2e-08 34.2 0.0 3.4 3 0 0 3 3 3 1 RUN domain DUF1664 PF07889.12 PVD36043.1 - 0.0039 17.2 6.4 0.0039 17.2 6.4 13.3 3 2 11 16 16 16 4 Protein of unknown function (DUF1664) GOLD_2 PF13897.6 PVD36043.1 - 0.0048 17.4 0.0 0.0048 17.4 0.0 4.9 4 1 1 5 5 5 1 Golgi-dynamics membrane-trafficking DUF4472 PF14739.6 PVD36043.1 - 0.0099 16.6 8.3 0.0099 16.6 8.3 13.4 2 2 9 15 15 15 1 Domain of unknown function (DUF4472) FYVE PF01363.21 PVD36043.1 - 0.03 14.4 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger LRR_6 PF13516.6 PVD36044.1 - 1.8e-19 68.0 24.7 0.048 13.7 0.0 10.6 11 0 0 11 11 11 7 Leucine Rich repeat F-box-like PF12937.7 PVD36044.1 - 1.6e-13 50.3 0.5 5.8e-13 48.5 0.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 PVD36044.1 - 3e-10 40.2 12.0 0.62 10.6 0.0 6.6 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) F-box PF00646.33 PVD36044.1 - 8.6e-08 31.9 0.5 2.7e-07 30.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PVD36044.1 - 0.0053 16.6 0.1 0.019 14.9 0.1 1.9 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 PVD36044.1 - 0.11 13.2 23.0 70 4.6 0.1 9.8 10 1 0 10 10 10 0 Leucine Rich Repeat MFS_1 PF07690.16 PVD36049.1 - 1.5e-42 145.8 15.2 2.2e-42 145.3 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36049.1 - 6.9e-07 28.5 2.4 6.9e-07 28.5 2.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter BRO1 PF03097.18 PVD36050.1 - 2.1e-115 385.7 5.5 2.1e-115 385.7 5.5 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 PVD36050.1 - 3.6e-89 299.0 8.3 3.6e-89 299.0 8.3 2.9 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV KxDL PF10241.9 PVD36050.1 - 0.0054 17.0 0.6 0.035 14.4 0.6 2.4 1 0 0 1 1 1 1 Uncharacterized conserved protein Y2_Tnp PF04986.13 PVD36050.1 - 0.11 12.5 0.1 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative transposase Lant_dehydr_C PF14028.6 PVD36050.1 - 1 8.8 4.6 4 6.9 0.1 3.0 3 0 0 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Spc29 PF17082.5 PVD36050.1 - 2.4 7.9 5.9 0.94 9.3 0.7 2.5 3 0 0 3 3 3 0 Spindle Pole Component 29 ABC_membrane PF00664.23 PVD36051.1 - 8.2e-57 192.9 32.6 4.6e-40 138.0 15.0 2.7 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD36051.1 - 2.1e-46 157.9 0.4 3.2e-27 95.7 0.0 3.6 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 PVD36051.1 - 1.3e-09 37.9 1.7 3.8e-05 23.2 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD36051.1 - 7.6e-08 32.4 0.6 0.00092 19.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD36051.1 - 1.3e-06 28.9 0.2 0.072 13.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PVD36051.1 - 1.6e-05 24.9 2.1 0.002 18.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PVD36051.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 2.7 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.12 PVD36051.1 - 0.0004 19.7 0.9 0.0097 15.2 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 PVD36051.1 - 0.00077 19.8 0.5 0.72 10.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PVD36051.1 - 0.0098 15.6 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PVD36051.1 - 0.022 14.6 0.8 6.7 6.4 0.1 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PVD36051.1 - 0.023 14.2 0.2 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 PVD36051.1 - 0.024 13.8 0.3 1.2 8.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 PVD36051.1 - 0.03 14.1 7.5 0.23 11.2 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 PVD36051.1 - 0.031 13.5 0.0 0.087 12.0 0.0 1.8 1 0 0 1 1 1 0 KAP family P-loop domain IIGP PF05049.13 PVD36051.1 - 0.032 13.3 0.3 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 PVD36051.1 - 0.039 13.1 0.6 2 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AIG1 PF04548.16 PVD36051.1 - 0.12 11.6 4.0 0.19 11.0 0.3 2.3 2 0 0 2 2 2 0 AIG1 family AAA_30 PF13604.6 PVD36051.1 - 0.16 11.7 2.1 16 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 PVD36051.1 - 0.17 12.1 1.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 PVD36051.1 - 0.19 11.3 3.1 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 PVD36051.1 - 0.41 11.1 11.1 1.1 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 PVD36051.1 - 2.3 8.2 11.5 1.7 8.7 0.2 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Sulfotransfer_2 PF03567.14 PVD36052.1 - 1.5e-17 64.4 0.9 6.5e-14 52.4 0.2 3.1 2 1 0 2 2 2 2 Sulfotransferase family SSP160 PF06933.11 PVD36053.1 - 0.0061 14.8 19.2 0.0057 14.9 19.2 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.17 PVD36053.1 - 0.047 13.7 27.0 0.051 13.6 27.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Rubella_E2 PF05749.11 PVD36053.1 - 0.21 11.0 6.8 0.2 11.1 6.8 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 FSA_C PF10479.9 PVD36053.1 - 1.3 7.1 9.6 1.3 7.0 9.6 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM154 PF15102.6 PVD36053.1 - 3.3 7.6 8.4 3.8 7.4 8.4 1.1 1 0 0 1 1 1 0 TMEM154 protein family Sulfotransfer_2 PF03567.14 PVD36054.1 - 1.1e-26 94.3 1.7 7.3e-23 81.8 0.1 2.2 2 0 0 2 2 2 2 Sulfotransferase family Colicin PF01024.19 PVD36054.1 - 0.035 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Colicin pore forming domain ubiquitin PF00240.23 PVD36055.1 - 4.3e-13 48.8 5.7 0.0004 20.1 0.2 4.3 5 0 0 5 5 5 3 Ubiquitin family Rad60-SLD PF11976.8 PVD36055.1 - 0.026 14.3 2.1 1 9.2 0.4 3.2 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like DUF1958 PF09211.10 PVD36055.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Ubiquitin_5 PF18037.1 PVD36055.1 - 0.12 12.7 1.5 1.8 9.0 0.0 2.9 2 1 1 3 3 3 0 Ubiquitin-like domain SWIRM-assoc_2 PF16496.5 PVD36056.1 - 3.1e-146 487.5 11.4 3.1e-146 487.5 11.4 2.3 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 PVD36056.1 - 8.6e-31 106.1 0.1 2.1e-30 104.9 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 PVD36056.1 - 8.8e-30 102.5 16.2 3.1e-29 100.8 16.2 2.0 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 PVD36056.1 - 8.6e-28 96.4 0.6 8.6e-28 96.4 0.6 2.9 3 0 0 3 3 3 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 PVD36056.1 - 3.1e-11 43.3 0.1 3.1e-11 43.3 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PVD36056.1 - 6.6e-06 26.3 1.1 1.6e-05 25.1 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Clat_adaptor_s PF01217.20 PVD36057.1 - 5.1e-34 117.2 0.6 6.5e-34 116.9 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5444 PF17519.2 PVD36057.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5444) MFS_1 PF07690.16 PVD36058.1 - 4.4e-63 213.3 27.8 5.4e-61 206.5 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36058.1 - 1.3e-08 34.1 27.6 2.4e-07 30.0 27.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter SLC3A2_N PF16028.5 PVD36058.1 - 0.055 13.0 0.0 0.28 10.8 0.0 2.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF3367 PF11847.8 PVD36058.1 - 0.24 9.2 2.2 0.41 8.5 0.1 2.0 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase HMG_box PF00505.19 PVD36061.1 - 6.3e-20 71.4 4.6 2e-19 69.8 4.6 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD36061.1 - 4.2e-08 33.7 2.9 4.2e-08 33.7 2.9 2.8 3 0 0 3 3 3 1 HMG-box domain DUF4587 PF15248.6 PVD36062.1 - 9.2e-09 36.0 6.6 9.2e-09 36.0 6.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4587) PMP22_Claudin PF00822.20 PVD36063.1 - 4e-14 52.8 3.5 1.7e-13 50.8 3.5 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD36063.1 - 1.8e-13 50.7 0.6 7.5e-12 45.4 0.6 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD36063.1 - 0.00052 20.0 0.6 0.0032 17.4 0.6 2.1 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Phage_holin_2_4 PF16082.5 PVD36063.1 - 0.22 11.2 0.7 0.59 9.9 0.7 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like zf-C2H2 PF00096.26 PVD36064.1 - 7.8e-19 67.0 70.0 0.0015 18.9 1.9 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD36064.1 - 2.4e-17 62.5 60.4 3.8e-07 30.2 1.9 8.0 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD36064.1 - 6.6e-17 60.7 65.8 0.039 14.8 0.9 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD36064.1 - 9.1e-10 38.1 32.2 8.8e-05 22.2 2.5 6.7 6 1 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 PVD36064.1 - 0.57 10.6 48.8 0.14 12.5 11.4 8.0 3 3 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PVD36064.1 - 3.4 8.2 34.1 0.78 10.2 3.5 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type SIS_2 PF13580.6 PVD36065.1 - 0.078 13.0 0.1 5.7 7.0 0.1 2.0 2 0 0 2 2 2 0 SIS domain tRNA-synt_2 PF00152.20 PVD36066.1 - 3.8e-73 246.3 0.0 6.2e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PVD36066.1 - 2.5e-07 30.6 1.0 4.9e-07 29.6 1.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PVD36066.1 - 5.4e-06 26.1 0.2 0.029 13.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MAS20 PF02064.15 PVD36066.1 - 0.34 11.0 6.5 0.7 10.0 6.5 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor NARP1 PF12569.8 PVD36066.1 - 1.1 8.1 8.6 1.7 7.5 8.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 PVD36066.1 - 5.2 7.5 8.0 8.4 6.8 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RhoGAP PF00620.27 PVD36067.1 - 5.4e-39 133.5 0.0 9.7e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SH2 PF00017.24 PVD36067.1 - 2.3e-13 50.0 0.0 1.2e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 SH2 domain C1_1 PF00130.22 PVD36067.1 - 7.7e-06 25.7 1.8 3e-05 23.8 0.6 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LicD PF04991.13 PVD36068.1 - 1.3e-12 48.4 0.0 5.7e-12 46.3 0.2 1.9 2 0 0 2 2 2 1 LicD family COPI_C PF06957.11 PVD36070.1 - 2.4e-188 625.9 0.0 3.5e-188 625.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 PVD36070.1 - 5.1e-142 474.0 0.2 9.8e-142 473.1 0.2 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 PVD36070.1 - 3.6e-42 141.5 16.8 7.1e-08 33.0 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36070.1 - 5.1e-09 36.3 0.4 0.0006 20.1 0.0 5.5 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 PVD36070.1 - 0.0039 17.9 0.7 5.9 8.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD36070.1 - 0.029 15.0 0.6 2.3 9.0 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup160 PF11715.8 PVD36070.1 - 0.61 8.7 6.2 2.4 6.7 0.1 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 IspD PF01128.19 PVD36071.1 - 2.1e-42 145.3 0.0 3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 PVD36071.1 - 1.3e-09 38.6 0.0 2.7e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 PVD36071.1 - 0.0002 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase zf-CCCH PF00642.24 PVD36072.1 - 2.6e-09 36.7 2.7 6.3e-09 35.5 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 PVD36072.1 - 3.2e-08 33.3 9.0 5.7e-08 32.5 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD36072.1 - 1e-06 28.4 11.7 2e-06 27.5 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36072.1 - 5.7e-06 26.1 13.1 1.2e-05 25.1 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36072.1 - 7.4e-06 25.8 14.1 1.3e-05 25.0 14.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 PVD36072.1 - 6.7e-05 22.8 4.4 6.7e-05 22.8 4.4 2.0 2 0 0 2 2 1 1 Zinc finger domain zf-RING_2 PF13639.6 PVD36072.1 - 7.9e-05 22.9 11.4 0.00016 22.0 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD36072.1 - 0.00011 22.1 11.3 0.00025 21.0 11.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD36072.1 - 0.00031 20.5 8.5 0.00061 19.6 8.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 PVD36072.1 - 0.00047 19.9 2.7 0.00047 19.9 2.7 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 PVD36072.1 - 0.00082 19.5 10.4 0.002 18.2 10.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PVD36072.1 - 0.023 14.8 6.5 0.023 14.8 6.5 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 PVD36072.1 - 0.033 14.0 6.5 0.063 13.1 6.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UBP PF02148.19 PVD36072.1 - 0.036 14.4 3.8 0.088 13.2 3.8 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-P11 PF03854.14 PVD36072.1 - 0.61 9.8 7.4 1.2 8.9 7.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-CCCH_2 PF14608.6 PVD36072.1 - 1.6 9.3 7.6 0.13 12.8 2.5 1.9 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 PVD36072.1 - 9.7 6.6 10.1 63 4.0 10.1 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain MFS_1_like PF12832.7 PVD36073.1 - 3.5e-90 302.6 1.9 4.5e-90 302.3 1.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PVD36073.1 - 4.1e-25 88.4 17.8 5.4e-15 55.2 13.3 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PVD36073.1 - 5.1e-09 35.6 19.3 1.2e-06 27.9 6.6 3.3 3 0 0 3 3 3 3 Nucleoside H+ symporter MFS_3 PF05977.13 PVD36073.1 - 0.0034 15.8 0.8 0.0034 15.8 0.8 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector LacY_symp PF01306.19 PVD36073.1 - 0.0054 15.6 14.5 0.18 10.6 0.3 2.6 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_2 PF13347.6 PVD36073.1 - 0.0071 15.0 17.5 0.026 13.1 1.3 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein UBX PF00789.20 PVD36074.1 - 6.2e-13 48.7 0.0 2e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 UBX domain SelK_SelG PF10961.8 PVD36074.1 - 0.085 13.5 0.7 0.085 13.5 0.7 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF3584 PF12128.8 PVD36074.1 - 0.61 7.5 31.1 0.85 7.1 31.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RAP1 PF07218.11 PVD36074.1 - 0.62 8.3 14.4 1.1 7.4 14.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LptF_LptG PF03739.14 PVD36074.1 - 10 4.9 11.6 0.2 10.5 0.2 2.2 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Methyltransf_22 PF13383.6 PVD36075.1 - 1e-21 77.7 0.8 1.3e-21 77.3 0.8 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 PVD36076.1 - 2e-39 134.1 6.7 5.2e-11 43.0 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD36076.1 - 6e-39 131.9 6.8 2.9e-10 40.5 0.3 8.0 3 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD36076.1 - 8e-30 102.5 9.2 1.2e-05 25.5 0.0 8.8 2 2 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD36076.1 - 4.2e-29 97.4 10.8 0.00031 21.0 0.0 10.2 11 0 0 11 11 9 6 Ankyrin repeat Ank PF00023.30 PVD36076.1 - 4.8e-27 93.2 7.6 3.8e-05 23.9 0.0 9.1 9 1 0 9 9 9 6 Ankyrin repeat TPR_2 PF07719.17 PVD36076.1 - 4.1e-09 35.8 9.3 0.033 14.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD36076.1 - 6.6e-06 25.7 6.2 0.026 14.2 0.4 3.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 PVD36076.1 - 9.4e-06 25.2 8.1 0.032 14.1 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD36076.1 - 1.8e-05 25.3 4.9 0.00043 20.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD36076.1 - 0.00029 20.8 8.1 0.023 14.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD36076.1 - 0.00031 21.2 6.5 0.011 16.3 1.4 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD36076.1 - 0.00038 20.7 0.5 0.00038 20.7 0.5 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PVD36076.1 - 0.0019 18.3 6.0 0.006 16.7 1.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD36076.1 - 0.014 16.2 4.4 0.73 10.8 1.4 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD36076.1 - 0.21 11.7 1.1 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD36076.1 - 3.1 8.6 7.5 12 6.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 PVD36077.1 - 0.0092 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 PVD36077.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein MEIOC PF15189.6 PVD36080.1 - 1.4e-80 268.8 4.5 3.2e-80 267.6 4.5 1.6 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC CAMSAP_CC1 PF17095.5 PVD36080.1 - 0.05 13.4 1.8 0.17 11.8 1.8 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Cation_efflux PF01545.21 PVD36081.1 - 1.6e-46 158.6 6.6 1.6e-46 158.6 6.6 1.6 2 1 0 2 2 2 1 Cation efflux family SUR7 PF06687.12 PVD36081.1 - 0.2 11.3 3.1 7 6.2 0.0 2.4 2 1 0 2 2 2 0 SUR7/PalI family DUF3278 PF11683.8 PVD36081.1 - 0.43 10.7 3.7 0.71 10.0 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) UreE_C PF05194.12 PVD36081.1 - 1.6 9.3 7.6 11 6.5 2.9 3.5 3 1 1 4 4 4 0 UreE urease accessory protein, C-terminal domain GT87 PF09594.10 PVD36082.1 - 0.044 13.5 0.3 0.077 12.7 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF2045 PF09741.9 PVD36082.1 - 0.048 13.0 0.9 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2045) Homeodomain PF00046.29 PVD36083.1 - 9.9e-20 70.2 6.1 1.4e-19 69.6 6.1 1.3 1 0 0 1 1 1 1 Homeodomain zf-RING_12 PF17976.1 PVD36085.1 - 0.012 15.9 0.2 0.025 14.8 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF789 PF05623.12 PVD36085.1 - 0.014 15.1 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) MIP PF00230.20 PVD36086.1 - 3.1e-60 203.7 4.6 4.2e-60 203.3 4.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF443 PF04276.12 PVD36086.1 - 0.0023 17.8 0.8 0.004 17.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF443) Glycophorin_A PF01102.18 PVD36086.1 - 0.014 15.6 0.0 4 7.7 0.0 2.7 3 0 0 3 3 3 0 Glycophorin A 7tm_1 PF00001.21 PVD36087.1 - 1.2e-21 77.2 13.7 2e-21 76.5 13.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD36087.1 - 1.2e-13 51.1 17.7 6.3e-08 32.3 6.8 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD36087.1 - 0.0014 18.3 8.5 0.0014 18.3 8.5 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Colicin_V PF02674.16 PVD36087.1 - 1.9 8.5 7.1 0.68 9.9 3.5 2.2 1 1 1 2 2 2 0 Colicin V production protein FGGY_N PF00370.21 PVD36089.1 - 9.5e-26 90.8 0.0 7.9e-19 68.2 0.0 2.4 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PVD36089.1 - 1.9e-18 66.9 0.0 7.3e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.25 PVD36090.1 - 2e-31 109.4 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD36090.1 - 7.6e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 PVD36090.1 - 1.1e-05 26.5 15.4 1.1e-05 26.5 15.4 1.7 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.6 PVD36090.1 - 0.0097 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PVD36090.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 PVD36090.1 - 0.033 14.1 0.0 0.19 11.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Toxin_TOLIP PF00087.21 PVD36090.1 - 2.4 8.5 13.3 7.6 6.9 13.3 2.0 1 1 0 1 1 1 0 Snake toxin and toxin-like protein bZIP_2 PF07716.15 PVD36091.1 - 6.3e-10 39.0 13.5 6.3e-10 39.0 13.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD36091.1 - 0.00017 21.7 12.5 0.00017 21.7 12.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD36091.1 - 1 9.9 9.4 0.2 12.2 5.9 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.32 PVD36092.1 - 8.2e-05 23.3 0.1 1.1 10.2 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36092.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_8 PF13621.6 PVD36093.1 - 9.3e-37 127.1 0.1 2.8e-36 125.5 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 PVD36093.1 - 8.8e-09 35.3 0.0 3.3e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PVD36093.1 - 6.8e-07 29.7 0.3 1.6e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Sulfatase PF00884.23 PVD36094.1 - 8.2e-53 179.8 0.6 1.1e-52 179.4 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PVD36094.1 - 0.00011 21.9 0.2 0.54 9.8 0.0 2.3 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 PVD36094.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 PVD36094.1 - 0.077 13.7 0.0 0.2 12.4 0.0 1.8 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase TIMELESS PF04821.14 PVD36095.1 - 9.3e-17 61.2 0.2 1e-16 61.1 0.2 1.0 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 PVD36096.1 - 4.8e-43 148.2 50.3 4.3e-22 79.0 0.4 3.9 2 1 1 3 3 3 2 Timeless protein C terminal region TIMELESS PF04821.14 PVD36096.1 - 4.2e-37 127.9 1.2 4.2e-37 127.9 1.2 2.9 3 0 0 3 3 3 1 Timeless protein DUF687 PF05095.12 PVD36096.1 - 0.13 10.7 0.3 0.22 10.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Laminin_EGF PF00053.24 PVD36097.1 - 3.2e-37 126.4 238.5 1.1e-05 25.5 12.1 13.1 4 3 8 12 12 12 12 Laminin EGF domain EGF_2 PF07974.13 PVD36097.1 - 1.2e-11 44.7 279.0 0.0069 16.7 12.6 21.3 14 8 6 20 20 20 11 EGF-like domain hEGF PF12661.7 PVD36097.1 - 0.00039 20.9 36.8 0.0067 17.0 3.6 18.6 17 5 2 19 19 19 8 Human growth factor-like EGF DSL PF01414.19 PVD36097.1 - 0.0074 16.5 262.4 0.058 13.7 14.1 12.3 11 1 1 12 12 12 9 Delta serrate ligand TMEM154 PF15102.6 PVD36097.1 - 0.12 12.3 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 PVD36097.1 - 0.19 12.6 0.4 0.48 11.3 0.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Flp1_like PF16982.5 PVD36097.1 - 0.4 10.1 4.2 0.69 9.4 4.2 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF1388 PF07142.12 PVD36098.1 - 9.2e-15 54.3 22.8 0.00053 19.9 2.8 5.0 1 1 2 3 3 3 3 Repeat of unknown function (DUF1388) Herpes_BLLF1 PF05109.13 PVD36098.1 - 3e-07 28.8 0.6 3.3e-07 28.7 0.6 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Nuc_recep-AF1 PF11825.8 PVD36098.1 - 1.2e-05 25.3 2.0 0.4 10.7 0.2 3.1 1 1 2 3 3 3 3 Nuclear/hormone receptor activator site AF-1 COG2 PF06148.11 PVD36098.1 - 0.0092 16.1 0.0 6.9 6.8 0.0 2.6 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 NCOA_u2 PF16665.5 PVD36098.1 - 3.9 7.8 8.2 52 4.2 0.7 3.8 1 1 1 2 2 2 0 Unstructured region on nuclear receptor coactivator protein MFS_1 PF07690.16 PVD36099.1 - 2.2e-26 92.6 95.6 2.2e-14 53.1 43.5 4.5 3 1 1 4 4 4 4 Major Facilitator Superfamily DUF4878 PF12870.7 PVD36099.1 - 0.69 10.2 3.2 1.2 9.4 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) MFS_1 PF07690.16 PVD36100.1 - 1.3e-16 60.5 40.8 6.8e-16 58.1 40.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36100.1 - 0.00032 19.7 3.3 0.00032 19.7 3.3 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Peptidase_S46 PF10459.9 PVD36100.1 - 0.14 10.8 2.4 0.19 10.3 2.4 1.0 1 0 0 1 1 1 0 Peptidase S46 CrgA PF06781.12 PVD36100.1 - 0.24 11.5 1.4 3.6 7.7 0.0 3.1 2 0 0 2 2 2 0 Cell division protein CrgA STT3 PF02516.14 PVD36101.1 - 1.2e-146 489.5 41.4 1.2e-143 479.6 38.1 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit QVR PF17064.5 PVD36102.1 - 9.5e-08 32.2 2.4 1.1e-07 32.0 2.4 1.1 1 0 0 1 1 1 1 Sleepless protein CD225 PF04505.12 PVD36103.1 - 0.1 12.8 1.2 0.19 11.9 1.0 1.6 1 1 0 1 1 1 0 Interferon-induced transmembrane protein An_peroxidase PF03098.15 PVD36104.1 - 2.4e-117 392.7 0.0 3.4e-117 392.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 PVD36104.1 - 2.1e-28 99.4 0.0 3.8e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PVD36104.1 - 5.4e-17 61.8 0.0 1.7e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 PVD36104.1 - 2.5e-14 53.5 18.4 6.7e-14 52.1 18.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 PVD36104.1 - 4.9e-10 39.7 2.6 0.00088 19.7 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD36104.1 - 1.2e-07 31.1 1.4 0.0009 19.0 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PVD36104.1 - 8.4e-06 25.0 6.8 0.00015 21.1 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PVD36104.1 - 2.7e-05 23.9 1.0 0.00021 21.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD36104.1 - 0.0084 15.6 1.8 0.017 14.6 0.1 2.5 2 0 0 2 2 2 1 EF hand DuoxA PF10204.9 PVD36105.1 - 4.1e-69 232.7 6.2 5.1e-69 232.4 6.2 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Ac81 PF05820.11 PVD36105.1 - 0.18 11.4 0.7 0.37 10.3 0.7 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 7tm_1 PF00001.21 PVD36106.1 - 3.8e-06 26.4 0.1 4.5e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 PVD36106.1 - 8.3e-05 21.9 0.1 9.7e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor VMA21 PF09446.10 PVD36106.1 - 0.00036 20.6 1.5 0.0035 17.4 0.0 2.1 1 1 1 2 2 2 1 VMA21-like domain 7TM_GPCR_Srw PF10324.9 PVD36106.1 - 0.0011 18.3 1.0 0.0013 18.1 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Frizzled PF01534.17 PVD36106.1 - 0.024 13.7 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region TMEM70 PF06979.12 PVD36106.1 - 0.04 14.3 0.1 0.04 14.3 0.1 1.6 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Sigma_reg_N PF13800.6 PVD36106.1 - 0.04 14.2 0.6 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PGA2 PF07543.12 PVD36106.1 - 0.059 13.4 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 7TM_GPCR_Sru PF10322.9 PVD36106.1 - 0.06 12.7 1.6 0.079 12.3 1.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Ca_hom_mod PF14798.6 PVD36106.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF4834 PF16118.5 PVD36106.1 - 0.18 12.8 2.2 1.6 9.7 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) zf-LITAF-like PF10601.9 PVD36106.1 - 0.2 11.9 0.3 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2768 PF10966.8 PVD36106.1 - 0.24 11.9 6.9 1.7 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DUF4405 PF14358.6 PVD36106.1 - 0.28 11.8 4.5 7.3 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) 7tm_1 PF00001.21 PVD36107.1 - 2.6e-05 23.7 0.1 3.5e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 PVD36107.1 - 0.00064 19.0 0.6 0.00074 18.8 0.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7TM_GPCR_Srw PF10324.9 PVD36107.1 - 0.0025 17.1 0.6 0.0028 17.0 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2768 PF10966.8 PVD36107.1 - 0.026 15.0 6.8 1.3 9.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) Frizzled PF01534.17 PVD36107.1 - 0.1 11.6 0.4 0.14 11.2 0.4 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region VMA21 PF09446.10 PVD36107.1 - 0.22 11.6 4.7 0.24 11.5 0.5 2.2 1 1 1 2 2 2 0 VMA21-like domain Sigma_reg_N PF13800.6 PVD36107.1 - 0.39 11.0 1.7 0.8 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4405 PF14358.6 PVD36107.1 - 0.42 11.2 4.6 10 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) WD40 PF00400.32 PVD36110.1 - 3.1e-49 163.9 34.9 9.4e-09 35.8 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36110.1 - 3.3e-20 72.2 9.7 0.011 16.0 0.5 6.4 2 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PVD36110.1 - 2.2e-08 32.6 3.8 2.2e-08 32.6 0.6 2.1 2 0 0 2 2 2 1 IKI3 family eIF2A PF08662.11 PVD36110.1 - 5.6e-07 29.6 2.4 0.33 10.8 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD36110.1 - 2.5e-06 26.7 0.8 0.22 10.5 0.0 4.5 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 PVD36110.1 - 0.00065 18.9 3.2 1.4 7.9 0.9 4.0 2 1 1 3 3 3 2 Coatomer WD associated region DUF4082 PF13313.6 PVD36110.1 - 0.19 11.8 3.9 6.3 6.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4082) EGF_CA PF07645.15 PVD36111.1 - 9.8e-72 236.9 834.9 3.5e-11 43.1 7.3 47.2 45 3 2 47 47 47 28 Calcium-binding EGF domain cEGF PF12662.7 PVD36111.1 - 7.8e-71 233.5 437.3 2.7e-07 30.4 3.7 48.3 47 0 0 47 47 47 28 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36111.1 - 2.4e-21 75.7 114.1 8.3e-09 35.6 12.2 46.9 31 13 16 47 47 47 24 Coagulation Factor Xa inhibitory site SEA PF01390.20 PVD36111.1 - 2.6e-08 33.9 2.0 2.5e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 SEA domain NIDO PF06119.14 PVD36111.1 - 1.1e-07 32.7 0.0 4e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 Nidogen-like EGF_MSP1_1 PF12946.7 PVD36111.1 - 1.6e-07 31.3 6.0 1.6e-07 31.3 6.0 34.5 38 2 2 40 40 40 8 MSP1 EGF domain 1 hEGF PF12661.7 PVD36111.1 - 2.8e-06 27.7 586.6 0.0006 20.3 9.8 49.3 48 2 0 48 48 48 27 Human growth factor-like EGF EGF_3 PF12947.7 PVD36111.1 - 0.0016 18.6 25.6 0.0029 17.7 4.4 48.3 43 5 3 46 46 46 22 EGF domain Plasmod_Pvs28 PF06247.11 PVD36111.1 - 0.0038 17.5 5.4 0.0038 17.5 5.4 36.4 37 4 2 39 39 39 12 Pvs28 EGF domain SKG6 PF08693.10 PVD36111.1 - 0.0091 15.4 3.9 0.021 14.2 3.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AICARFT_IMPCHas PF01808.18 PVD36112.1 - 5.9e-92 308.3 0.0 7.6e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 PVD36112.1 - 8.3e-24 83.6 0.0 1.8e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain MFS_1 PF07690.16 PVD36113.1 - 1.6e-17 63.5 40.7 1.6e-17 63.5 40.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 PVD36114.1 - 1.8e-18 66.6 43.9 1.4e-10 40.7 12.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DNA_pol_phi PF04931.13 PVD36114.1 - 0.05 11.7 12.8 0.067 11.3 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rhabdo_ncap PF00945.18 PVD36114.1 - 2.8 6.7 5.7 4.2 6.1 5.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein MFS_1 PF07690.16 PVD36115.1 - 5.9e-10 38.6 41.6 1e-08 34.5 17.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PsbN PF02468.15 PVD36115.1 - 0.024 14.5 1.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) MFS_1 PF07690.16 PVD36116.1 - 8.3e-13 48.0 29.2 3.2e-08 32.9 15.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily GAPT PF11770.8 PVD36116.1 - 0.096 12.6 0.9 0.72 9.7 0.1 2.1 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) MFS_1 PF07690.16 PVD36117.1 - 0.0064 15.5 0.1 0.0068 15.4 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Abi_HHR PF07815.14 PVD36118.1 - 3.2e-29 100.9 0.1 5.6e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 PVD36118.1 - 2.7e-18 65.5 0.1 8.1e-18 64.0 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PVD36118.1 - 2.3e-15 55.9 0.4 3.9e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD36118.1 - 1.9e-11 43.4 0.1 3.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sema PF01403.19 PVD36119.1 - 3.6e-89 299.5 0.9 3.2e-57 194.3 0.2 2.2 1 1 1 2 2 2 2 Sema domain PSI PF01437.25 PVD36119.1 - 3.5e-08 33.9 3.3 3.5e-08 33.9 3.3 3.5 4 0 0 4 4 4 1 Plexin repeat TSP_1 PF00090.19 PVD36119.1 - 6.4e-06 26.3 13.1 9.4e-06 25.8 4.1 5.5 5 1 0 5 5 5 3 Thrombospondin type 1 domain EGF_CA PF07645.15 PVD36122.1 - 2.3e-30 104.5 88.9 1.6e-08 34.6 7.5 16.6 14 2 2 16 16 16 7 Calcium-binding EGF domain VWD PF00094.25 PVD36122.1 - 9.8e-19 68.2 0.1 1e-17 64.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_3 PF12947.7 PVD36122.1 - 3.8e-15 55.8 52.8 6.5e-06 26.2 2.2 18.6 18 1 0 18 18 18 11 EGF domain cEGF PF12662.7 PVD36122.1 - 1.1e-11 44.4 123.5 0.00021 21.1 0.6 15.7 15 0 0 15 15 15 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD36122.1 - 0.00057 20.1 5.5 0.00057 20.1 5.5 18.1 12 2 5 17 17 17 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD36122.1 - 0.00065 19.9 6.9 0.00065 19.9 6.9 19.5 19 0 0 19 19 19 9 EGF-like domain EGF_MSP1_1 PF12946.7 PVD36122.1 - 0.0023 17.9 6.1 0.0023 17.9 6.1 14.5 13 1 1 14 14 14 7 MSP1 EGF domain 1 7tm_1 PF00001.21 PVD36123.1 - 4.1e-37 127.9 1.3 1e-36 126.7 1.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD36123.1 - 2.9e-08 33.4 4.1 0.0021 17.5 0.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 PVD36123.1 - 2.6e-05 23.7 6.5 0.0067 15.8 0.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Chromate_transp PF02417.15 PVD36123.1 - 0.15 12.2 1.2 0.65 10.1 1.2 1.8 2 0 0 2 2 2 0 Chromate transporter DUF4834 PF16118.5 PVD36123.1 - 0.88 10.6 0.0 0.88 10.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) BPD_transp_1 PF00528.22 PVD36123.1 - 1.8 8.2 5.9 0.42 10.3 2.2 1.7 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component 7tm_1 PF00001.21 PVD36124.1 - 2.3e-13 50.1 0.1 2.3e-13 50.1 0.1 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD36124.1 - 2.9e-05 24.0 0.7 4.3e-05 23.4 0.4 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD36124.1 - 0.0035 16.8 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Phage_holin_3_6 PF07332.11 PVD36124.1 - 0.08 13.0 2.2 0.11 12.5 2.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MENTAL PF10457.9 PVD36129.1 - 2.9e-59 199.8 7.9 4.1e-59 199.4 7.9 1.2 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 PVD36129.1 - 2.5e-32 112.0 0.0 3.4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 START domain ATP-synt_F PF01990.17 PVD36130.1 - 5.3e-18 65.1 3.1 1.9e-10 40.9 0.4 2.3 1 1 1 2 2 2 2 ATP synthase (F/14-kDa) subunit ubiquitin PF00240.23 PVD36131.1 - 2.4e-07 30.4 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PVD36131.1 - 0.04 13.7 0.4 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like 7tm_1 PF00001.21 PVD36132.1 - 1.4e-08 34.4 8.0 4.2e-07 29.6 1.0 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD36132.1 - 0.00095 18.5 8.3 0.0096 15.2 1.0 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Sulfotransfer_1 PF00685.27 PVD36133.1 - 3.4e-19 69.4 1.3 9.9e-19 67.8 1.3 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD36133.1 - 5.9e-12 46.4 0.1 9.9e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family TauE PF01925.19 PVD36134.1 - 0.11 12.2 9.6 0.019 14.6 5.5 1.9 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE DUF1361 PF07099.11 PVD36134.1 - 0.31 11.0 7.9 2.8 7.9 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) ANF_receptor PF01094.28 PVD36135.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region EphA2_TM PF14575.6 PVD36136.1 - 0.1 13.5 0.6 4.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ninjurin PF04923.12 PVD36136.1 - 0.13 12.2 2.4 1.7 8.7 0.3 2.1 2 0 0 2 2 2 0 Ninjurin DUF3430 PF11912.8 PVD36136.1 - 0.21 11.6 0.5 0.3 11.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) TMEM154 PF15102.6 PVD36136.1 - 0.46 10.4 3.3 13 5.7 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family MMPL PF03176.15 PVD36136.1 - 6.7 5.5 7.6 0.29 10.0 0.1 2.0 2 0 0 2 2 2 0 MMPL family Guanylate_cyc PF00211.20 PVD36137.1 - 2.9e-49 167.2 2.1 1e-34 119.8 0.8 6.2 2 1 2 4 4 4 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD36137.1 - 1.5e-23 83.4 0.1 2.2e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36137.1 - 5.9e-21 75.0 0.0 9e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 PVD36137.1 - 0.00051 19.5 1.8 0.00073 19.0 1.8 1.2 1 0 0 1 1 1 1 Heme NO binding associated Zona_pellucida PF00100.23 PVD36138.1 - 3.3e-07 30.4 1.1 4.3e-07 30.0 1.1 1.3 1 1 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 PVD36138.1 - 6e-05 23.2 12.6 6e-05 23.2 12.6 3.1 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 PVD36138.1 - 0.062 13.7 27.6 0.16 12.4 14.6 2.9 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 PVD36138.1 - 0.18 12.5 19.6 0.47 11.2 9.9 3.6 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 PVD36138.1 - 0.47 10.6 21.5 0.17 12.0 6.2 2.7 2 0 0 2 2 2 0 Laminin EGF domain Homeodomain PF00046.29 PVD36139.1 - 1.2e-10 41.0 2.4 2.3e-10 40.1 2.4 1.5 1 0 0 1 1 1 1 Homeodomain MPDZ_u10 PF16667.5 PVD36140.1 - 5.1 8.1 25.8 44 5.1 0.1 7.1 1 1 8 9 9 9 0 Unstructured region 10 on multiple PDZ protein 7tm_1 PF00001.21 PVD36141.1 - 5.4e-17 62.0 13.8 4.8e-14 52.3 3.9 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD36141.1 - 1.5e-05 24.5 5.4 1.5e-05 24.5 5.4 2.5 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 PVD36141.1 - 0.00028 20.3 16.0 0.029 13.7 4.6 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw TM231 PF10149.9 PVD36141.1 - 0.0092 15.4 4.2 0.024 14.0 4.2 1.6 1 0 0 1 1 1 1 Transmembrane protein 231 SNARE PF05739.19 PVD36141.1 - 0.028 14.4 0.7 0.028 14.4 0.7 2.5 2 0 0 2 2 2 0 SNARE domain Ac76 PF05814.11 PVD36141.1 - 0.029 14.4 0.9 6.8 6.8 0.3 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) TIR_2 PF13676.6 PVD36142.1 - 0.0098 16.5 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD36144.1 - 9.8e-06 26.2 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain Death PF00531.22 PVD36144.1 - 5.7e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Death domain TIR PF01582.20 PVD36144.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 TIR domain Kunitz_BPTI PF00014.23 PVD36145.1 - 7e-17 61.4 6.9 1.3e-16 60.5 6.9 1.5 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Endonuclease_NS PF01223.23 PVD36145.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease EphA2_TM PF14575.6 PVD36147.1 - 0.0047 17.8 0.4 0.0047 17.8 0.4 1.9 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 PVD36147.1 - 0.0079 16.5 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PRIMA1 PF16101.5 PVD36147.1 - 0.4 10.7 0.0 0.4 10.7 0.0 1.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Trypsin PF00089.26 PVD36148.1 - 1.8e-63 214.3 1.6 3.6e-63 213.3 1.6 1.6 1 0 0 1 1 1 1 Trypsin Collagen PF01391.18 PVD36148.1 - 6.3e-55 182.8 216.9 5.8e-09 35.6 26.4 7.4 2 2 5 7 7 7 7 Collagen triple helix repeat (20 copies) I-set PF07679.16 PVD36148.1 - 1.3e-26 92.5 0.0 2.8e-12 46.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36148.1 - 3e-26 91.8 0.5 4.9e-14 52.7 0.2 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD36148.1 - 1.5e-16 60.3 0.2 7.6e-08 32.4 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD36148.1 - 8.3e-16 58.1 0.4 1.9e-07 31.3 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain LCCL PF03815.19 PVD36148.1 - 4e-13 49.3 2.4 9.3e-13 48.1 2.4 1.5 1 0 0 1 1 1 1 LCCL domain V-set PF07686.17 PVD36148.1 - 9.7e-07 28.9 2.2 0.48 10.6 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 PVD36148.1 - 7.1e-06 26.3 0.0 0.00076 19.8 0.0 2.5 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF1986 PF09342.11 PVD36148.1 - 0.00018 21.9 0.2 0.00018 21.9 0.2 2.2 3 0 0 3 3 2 1 Domain of unknown function (DUF1986) Ig_4 PF16680.5 PVD36148.1 - 0.0046 17.2 0.2 1.3 9.4 0.0 2.9 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 PVD36148.1 - 0.058 13.4 0.1 0.51 10.4 0.0 2.3 2 1 0 2 2 2 0 C17orf99 Ig domain Trypsin PF00089.26 PVD36149.1 - 1e-58 198.8 2.9 1.8e-58 198.0 2.9 1.4 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD36149.1 - 1.6e-06 28.5 0.1 2.9e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD36149.1 - 5.1e-05 24.2 1.3 0.001 19.9 0.1 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain Ependymin PF00811.18 PVD36150.1 - 1.8e-07 31.5 0.1 3e-07 30.8 0.1 1.3 1 1 0 1 1 1 1 Ependymin Ependymin PF00811.18 PVD36151.1 - 8.5e-05 22.8 0.1 0.001 19.3 0.1 2.2 1 1 0 1 1 1 1 Ependymin Emaravirus_P4 PF16505.5 PVD36151.1 - 0.02 13.9 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Herpes_UL17 PF04559.12 PVD36152.1 - 0.06 12.1 14.7 0.081 11.7 14.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein Flot PF15975.5 PVD36152.1 - 0.13 12.5 26.8 0.038 14.2 11.5 2.5 1 1 1 2 2 2 0 Flotillin Golgin_A5 PF09787.9 PVD36152.1 - 0.2 11.1 22.6 0.18 11.2 18.1 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 PK PF00224.21 PVD36153.1 - 3.1e-161 536.1 2.6 3.9e-161 535.7 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PVD36153.1 - 3.4e-34 117.6 0.2 9e-34 116.2 0.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PVD36153.1 - 0.0022 17.1 0.3 0.0067 15.6 0.1 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ANF_receptor PF01094.28 PVD36154.1 - 9.4e-60 202.6 0.0 1.3e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Guanylate_cyc PF00211.20 PVD36154.1 - 3.2e-43 147.5 0.0 3e-41 141.1 0.0 2.3 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD36154.1 - 3e-28 98.8 0.1 3.9e-27 95.2 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36154.1 - 2.4e-18 66.4 0.0 9.4e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 PVD36154.1 - 6.8e-07 29.3 0.0 6e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 PVD36155.1 - 3.7e-05 23.0 0.0 5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1891 PF09004.10 PVD36156.1 - 4.6e-09 35.7 0.1 7.9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) SNF PF00209.18 PVD36157.1 - 2.1e-12 46.6 24.8 7.9e-12 44.6 24.8 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Aminotran_5 PF00266.19 PVD36158.1 - 2.7e-48 164.8 0.0 3.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V NIF PF03031.18 PVD36159.1 - 5.6e-52 175.7 0.4 8.4e-52 175.1 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase KH_1 PF00013.29 PVD36160.1 - 4.3e-29 100.2 9.7 4.4e-15 55.2 0.4 2.7 3 0 0 3 3 3 2 KH domain TUDOR PF00567.24 PVD36160.1 - 5.3e-29 100.7 0.0 1.3e-28 99.5 0.0 1.6 2 0 0 2 2 2 1 Tudor domain KH_4 PF13083.6 PVD36160.1 - 2.5e-07 30.5 2.0 0.0047 16.8 0.2 2.8 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 PVD36160.1 - 4e-05 23.3 9.4 0.037 13.8 0.7 2.7 1 1 0 2 2 2 2 KH domain KH_5 PF13184.6 PVD36160.1 - 0.063 13.4 2.0 6.7 6.9 0.1 2.6 2 0 0 2 2 2 0 NusA-like KH domain DLH PF01738.18 PVD36160.1 - 0.13 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Fasciclin PF02469.22 PVD36162.1 - 5e-26 91.4 0.3 1.1e-09 38.5 0.0 3.1 3 0 0 3 3 3 3 Fasciclin domain Fasciclin PF02469.22 PVD36163.1 - 2.6e-48 163.5 0.1 2e-13 50.7 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain Ferrochelatase PF00762.19 PVD36165.1 - 5.5e-81 272.1 0.0 1.1e-79 267.8 0.0 2.0 1 1 0 1 1 1 1 Ferrochelatase Glyco_transf_11 PF01531.16 PVD36166.1 - 1.5e-36 126.1 0.0 7.9e-36 123.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 11 zf-H2C2_2 PF13465.6 PVD36167.1 - 8.4e-07 29.1 0.2 8.4e-07 29.1 0.2 5.0 4 1 1 5 5 5 1 Zinc-finger double domain Vps36-NZF-N PF16988.5 PVD36167.1 - 0.0033 16.8 0.1 0.0033 16.8 0.1 2.8 3 0 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_4 PF13894.6 PVD36167.1 - 0.011 16.5 0.3 0.011 16.5 0.3 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger Cys_rich_CPXG PF14255.6 PVD36167.1 - 0.063 13.2 0.2 0.063 13.2 0.2 2.6 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-C2H2 PF00096.26 PVD36167.1 - 0.079 13.4 0.2 0.079 13.4 0.2 5.0 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 PVD36167.1 - 0.13 13.0 8.0 7.5 7.3 2.9 2.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 PVD36167.1 - 2.6 7.7 12.1 1.2 8.8 0.1 3.5 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain NHL PF01436.21 PVD36168.1 - 0.1 12.7 4.3 1.4 9.0 0.0 4.1 5 0 0 5 5 5 0 NHL repeat Nas2_N PF18265.1 PVD36168.1 - 0.13 12.2 0.5 8.4 6.4 0.0 2.5 1 1 1 2 2 2 0 Nas2 N_terminal domain Kelch_1 PF01344.25 PVD36168.1 - 0.16 11.6 0.3 0.76 9.4 0.2 2.2 2 0 0 2 2 2 0 Kelch motif SBBP PF06739.11 PVD36168.1 - 0.26 11.3 1.1 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 Beta-propeller repeat Sushi PF00084.20 PVD36170.1 - 5.9e-16 58.8 10.9 4.4e-10 40.0 3.3 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Zn_ribbon_2 PF12674.7 PVD36170.1 - 0.66 10.7 6.0 0.39 11.4 0.2 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain EB PF01683.18 PVD36171.1 - 7.2e-12 45.4 23.9 3.2e-06 27.3 8.1 2.2 1 1 1 2 2 2 2 EB module TMEM154 PF15102.6 PVD36171.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 PVD36171.1 - 0.0023 17.6 0.4 0.004 16.9 0.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PVD36171.1 - 0.0027 18.6 0.0 0.005 17.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PVD36171.1 - 0.0031 17.4 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 CD34_antigen PF06365.12 PVD36171.1 - 0.0031 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family UPF0560 PF10577.9 PVD36171.1 - 0.0081 14.7 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 LRRC37AB_C PF14914.6 PVD36171.1 - 0.028 14.3 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Tweety PF04906.13 PVD36171.1 - 0.044 12.4 0.1 0.064 11.9 0.1 1.1 1 0 0 1 1 1 0 Tweety Tmemb_9 PF05434.11 PVD36171.1 - 0.049 13.5 0.2 0.09 12.7 0.2 1.6 1 1 0 1 1 1 0 TMEM9 Comm PF15957.5 PVD36171.1 - 0.072 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Commissureless Flu_M2 PF00599.17 PVD36171.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M2) SRTM1 PF15872.5 PVD36171.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF2207 PF09972.9 PVD36171.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gemini_mov PF01708.16 PVD36171.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Orf78 PF06024.12 PVD36171.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Syndecan PF01034.20 PVD36171.1 - 0.14 12.1 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 PVD36171.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor S_locus_glycop PF00954.20 PVD36171.1 - 0.41 11.2 17.5 0.27 11.8 4.2 2.4 2 0 0 2 2 2 0 S-locus glycoprotein domain EB PF01683.18 PVD36172.1 - 0 1288.1 2165.3 1.1e-06 28.9 14.0 142.1 12 11 130 142 142 142 141 EB module WW PF00397.26 PVD36173.1 - 8.6e-10 38.5 1.0 1.9e-09 37.5 1.0 1.6 1 0 0 1 1 1 1 WW domain YL1 PF05764.13 PVD36173.1 - 0.14 12.2 5.8 0.15 12.2 3.1 1.9 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 PVD36173.1 - 0.38 9.0 1.6 0.43 8.8 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_A22B PF04258.13 PVD36174.1 - 2.1e-65 221.1 18.9 2.1e-65 221.1 18.9 1.5 2 0 0 2 2 2 1 Signal peptide peptidase PA PF02225.22 PVD36174.1 - 5.9e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF2254 PF10011.9 PVD36174.1 - 0.84 8.4 0.0 0.84 8.4 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) Orf78 PF06024.12 PVD36174.1 - 5 7.5 4.7 1 9.7 0.2 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Pyr_redox_2 PF07992.14 PVD36175.1 - 0.0013 18.0 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Claudin_2 PF13903.6 PVD36177.1 - 7.6 6.2 14.0 3.9e+02 0.7 13.6 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ig_3 PF13927.6 PVD36178.1 - 7.2e-05 23.3 0.1 0.042 14.4 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD36178.1 - 0.00013 22.1 0.4 0.00058 20.0 0.0 2.2 2 2 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD36178.1 - 0.0003 21.1 0.2 0.014 15.7 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD36178.1 - 0.001 19.1 0.0 3.1 7.9 0.0 3.3 1 1 1 3 3 3 2 Immunoglobulin I-set domain Big_3_2 PF12245.8 PVD36178.1 - 0.025 14.8 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain Ig_6 PF18452.1 PVD36178.1 - 0.029 13.9 0.0 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain CARD PF00619.21 PVD36179.1 - 3.4e-11 43.0 0.4 3.4e-11 43.0 0.4 2.4 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 PVD36179.1 - 1e-05 25.4 2.9 1.7e-05 24.7 0.1 2.8 3 0 0 3 3 3 1 Caspase recruitment domain HalX PF08663.10 PVD36179.1 - 0.13 12.6 5.9 0.45 10.9 5.9 1.9 1 0 0 1 1 1 0 HalX domain HMG_box PF00505.19 PVD36180.1 - 6.8e-23 80.9 1.1 1.5e-22 79.8 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD36180.1 - 5.8e-15 55.6 1.2 1.4e-14 54.5 1.2 1.7 1 0 0 1 1 1 1 HMG-box domain DUF4763 PF15960.5 PVD36180.1 - 0.0044 16.4 1.6 0.0044 16.4 1.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) DUF3584 PF12128.8 PVD36180.1 - 0.012 13.2 12.2 0.016 12.8 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 PVD36180.1 - 0.017 14.5 4.9 0.021 14.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMCO5 PF14992.6 PVD36180.1 - 0.018 14.7 1.4 0.018 14.7 1.4 1.5 2 0 0 2 2 2 0 TMCO5 family HMG_box_5 PF14887.6 PVD36180.1 - 0.033 14.1 0.2 0.089 12.8 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF16 PF01519.16 PVD36180.1 - 0.036 14.6 0.2 0.11 13.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 PVD36180.1 - 0.058 13.5 2.5 0.11 12.6 1.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF812 PF05667.11 PVD36180.1 - 0.067 12.1 10.7 0.17 10.7 10.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1043 PF06295.12 PVD36180.1 - 0.69 9.9 4.7 0.16 11.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ATG16 PF08614.11 PVD36180.1 - 0.97 9.6 14.9 2.8 8.1 14.9 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 PVD36180.1 - 1.1 9.9 7.9 0.13 12.9 1.3 2.4 2 1 0 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 PVD36180.1 - 1.7 8.2 10.6 6.2 6.3 10.6 1.8 1 1 0 1 1 1 0 PspA/IM30 family Med4 PF10018.9 PVD36180.1 - 2.1 8.0 9.1 0.052 13.2 1.9 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 MbeD_MobD PF04899.12 PVD36180.1 - 2.1 8.5 7.8 6.1 7.0 0.7 2.7 2 0 0 2 2 2 0 MbeD/MobD like Spc24 PF08286.11 PVD36180.1 - 3.7 7.8 5.6 0.58 10.4 0.9 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PIP5K PF01504.18 PVD36182.1 - 2.9e-91 305.5 0.2 4.1e-91 305.0 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-met PF12874.7 PVD36184.1 - 0.0013 19.0 6.3 0.0015 18.9 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Fmp27 PF10344.9 PVD36184.1 - 0.046 11.8 1.6 0.065 11.3 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Desulfoferrod_N PF06397.12 PVD36184.1 - 0.24 11.1 2.0 0.82 9.4 0.6 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-Di19 PF05605.12 PVD36184.1 - 1.1 9.6 8.6 2.1 8.7 8.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LPMO_10 PF03067.15 PVD36185.1 - 4.1e-35 122.2 2.9 1.1e-34 120.9 2.9 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Peptidase_M1 PF01433.20 PVD36186.1 - 2.3e-85 285.6 1.3 2.3e-85 285.6 1.3 2.2 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 PVD36186.1 - 1.6e-83 280.9 3.8 2.3e-83 280.3 3.8 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PVD36186.1 - 1.5e-48 165.4 1.5 2.8e-48 164.6 1.5 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ddrB-ParB PF18763.1 PVD36186.1 - 0.17 12.0 0.0 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 ddrB-like ParB superfamily domain Sulf_transp PF04143.14 PVD36187.1 - 3.1e-38 132.1 23.2 3.8e-38 131.8 23.2 1.1 1 0 0 1 1 1 1 Sulphur transport ANF_receptor PF01094.28 PVD36189.1 - 6e-21 74.9 0.0 7.3e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Guanylate_cyc PF00211.20 PVD36191.1 - 2.5e-54 183.7 0.0 1e-52 178.4 0.0 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD36191.1 - 3.9e-37 127.9 0.0 5.9e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 PVD36191.1 - 6e-33 114.4 0.0 9.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 PVD36191.1 - 1.7e-27 96.5 0.0 4.4e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 PVD36191.1 - 0.00014 21.4 0.5 0.00023 20.7 0.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated Kringle PF00051.18 PVD36192.1 - 4.8e-06 26.8 0.2 1.1e-05 25.7 0.2 1.6 1 0 0 1 1 1 1 Kringle domain Sushi PF00084.20 PVD36192.1 - 0.00018 22.1 0.0 0.0005 20.6 0.0 1.8 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Sushi PF00084.20 PVD36193.1 - 2.8e-05 24.6 2.2 2.8e-05 24.6 2.2 2.6 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) HRM PF02793.22 PVD36193.1 - 0.033 14.5 3.1 0.23 11.8 0.6 2.5 2 0 0 2 2 2 0 Hormone receptor domain Ig_3 PF13927.6 PVD36194.1 - 2e-05 25.1 0.2 0.0067 17.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD36194.1 - 7.4e-05 22.9 0.6 0.00031 20.9 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD36194.1 - 0.00034 20.9 0.2 0.0086 16.4 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD36194.1 - 0.0021 18.1 0.0 1.4 9.0 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD36194.1 - 0.01 16.0 0.8 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 PVD36194.1 - 0.014 14.9 0.0 0.87 9.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Big_3_2 PF12245.8 PVD36194.1 - 0.042 14.1 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain Sushi PF00084.20 PVD36195.1 - 2e-06 28.3 8.2 4.2e-05 24.1 2.2 2.9 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) HRM PF02793.22 PVD36195.1 - 0.079 13.3 1.2 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Hormone receptor domain V-set PF07686.17 PVD36196.1 - 4.1e-07 30.2 1.2 1.2e-06 28.6 0.1 2.3 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD36196.1 - 1.6e-05 25.4 1.1 0.0077 16.8 0.1 2.9 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD36196.1 - 0.00016 21.7 0.0 0.91 9.6 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36196.1 - 0.00053 20.3 1.4 0.0079 16.5 0.1 2.8 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD36196.1 - 0.011 15.9 2.1 0.91 9.7 0.1 2.6 2 1 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 PVD36196.1 - 0.045 13.3 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Big_3_2 PF12245.8 PVD36196.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain Ig_3 PF13927.6 PVD36197.1 - 8.8e-05 23.0 0.0 0.0034 17.9 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 PVD36197.1 - 0.0016 18.5 0.3 0.075 13.2 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD36197.1 - 0.0057 17.0 0.2 0.087 13.2 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD36197.1 - 0.0058 16.7 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain DUF2135 PF09906.9 PVD36197.1 - 0.086 13.2 0.1 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) Crystall_2 PF09076.10 PVD36197.1 - 0.13 12.2 1.0 0.49 10.3 1.0 1.9 1 0 0 1 1 1 0 Beta/Gamma crystallin RUN PF02759.19 PVD36198.1 - 0.0032 17.4 0.1 0.0083 16.1 0.1 1.8 1 0 0 1 1 1 1 RUN domain SH3_9 PF14604.6 PVD36198.1 - 0.025 14.5 0.2 0.05 13.5 0.2 1.4 1 0 0 1 1 1 0 Variant SH3 domain Ad_cyc_g-alpha PF08509.11 PVD36199.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain CDO_I PF05995.12 PVD36203.1 - 9.6e-58 194.2 0.3 1.4e-57 193.6 0.3 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 PVD36203.1 - 7.7e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Spore_GerAC PF05504.11 PVD36203.1 - 0.07 13.4 0.3 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal PTH2 PF01981.16 PVD36203.1 - 0.16 12.2 0.3 0.32 11.3 0.3 1.4 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 COMM_domain PF07258.14 PVD36204.1 - 5.4e-20 71.3 1.3 1.1e-19 70.4 1.3 1.5 1 0 0 1 1 1 1 COMM domain Ribosomal_L9_N PF01281.19 PVD36205.1 - 7.1e-15 54.3 0.0 1.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF1899 PF08953.11 PVD36206.1 - 7.8e-28 96.1 0.1 2.3e-27 94.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 PVD36206.1 - 3e-17 62.2 0.2 8.1e-17 60.9 0.2 1.8 1 1 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 PVD36206.1 - 5.5e-09 36.5 9.0 0.00013 22.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36206.1 - 1.7e-07 31.5 0.3 0.017 15.4 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FAM76 PF16046.5 PVD36206.1 - 0.084 12.2 3.7 0.16 11.3 3.7 1.4 1 0 0 1 1 1 0 FAM76 protein KLRAQ PF10205.9 PVD36206.1 - 0.21 11.8 1.7 0.45 10.8 1.7 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein CEP209_CC5 PF16574.5 PVD36206.1 - 0.3 11.3 1.8 0.6 10.3 1.8 1.4 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DivIC PF04977.15 PVD36206.1 - 0.58 10.0 3.4 1.2 9.0 3.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Transferrin PF00405.17 PVD36207.1 - 2.6e-124 414.7 7.6 1.1e-65 222.0 2.2 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 PVD36207.1 - 2e-19 70.1 0.0 9.9e-09 35.1 0.0 3.2 2 2 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein Cyclin_C_2 PF16899.5 PVD36208.1 - 3.4e-21 75.6 0.1 6.6e-19 68.2 0.0 2.9 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 PVD36208.1 - 2.9e-10 40.0 0.1 6.8e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C3HC4_3 PF13920.6 PVD36208.1 - 4.4e-08 32.8 9.0 4.4e-08 32.8 9.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36208.1 - 3.6e-07 30.1 9.3 3.6e-07 30.1 9.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36208.1 - 5.7e-07 29.3 9.1 5.7e-07 29.3 9.1 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36208.1 - 3.3e-06 27.0 8.9 3.3e-06 27.0 8.9 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36208.1 - 4.2e-06 27.0 8.6 4.2e-06 27.0 8.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.24 PVD36208.1 - 1.8e-05 24.8 10.1 1.8e-05 24.8 10.1 3.3 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD36208.1 - 2.8e-05 23.8 9.4 2.8e-05 23.8 9.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36208.1 - 7.4e-05 22.5 8.5 7.4e-05 22.5 8.5 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD36208.1 - 0.00015 21.9 10.3 0.00015 21.9 10.3 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Cyclin_C PF02984.19 PVD36208.1 - 0.0013 18.8 1.0 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain AAA_lid_10 PF17872.1 PVD36208.1 - 1.2 9.3 4.1 3 8.0 2.3 2.5 2 1 0 2 2 2 0 AAA lid domain Sin3a_C PF16879.5 PVD36209.1 - 2.5e-66 224.3 8.0 2.5e-66 224.3 8.0 2.1 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 PVD36209.1 - 5.9e-42 141.7 0.1 5.9e-42 141.7 0.1 2.7 3 0 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.21 PVD36209.1 - 2.5e-40 136.4 5.5 4.5e-20 71.5 1.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat MH2 PF03166.14 PVD36210.1 - 2.5e-50 171.3 0.3 7.6e-25 88.2 0.0 2.3 1 1 1 2 2 2 2 MH2 domain MH1 PF03165.16 PVD36210.1 - 5.8e-25 87.5 0.3 1.1e-24 86.6 0.3 1.5 1 0 0 1 1 1 1 MH1 domain APC_r PF05923.12 PVD36214.1 - 2.1e-60 199.4 62.3 9.1e-12 44.4 0.5 11.0 11 0 0 11 11 11 8 APC repeat APC_rep PF18797.1 PVD36214.1 - 3.1e-26 92.1 0.1 2.3e-25 89.3 0.1 2.7 1 0 0 1 1 1 1 Adenomatous polyposis coli (APC) repeat Arm PF00514.23 PVD36214.1 - 2.1e-23 81.6 15.3 1.4e-06 28.1 0.2 7.6 7 1 0 7 7 7 5 Armadillo/beta-catenin-like repeat Suppressor_APC PF11414.8 PVD36214.1 - 1.9e-16 59.9 7.0 1.9e-16 59.9 7.0 3.1 2 1 1 3 3 3 1 Adenomatous polyposis coli tumour suppressor protein SAMP PF05924.11 PVD36214.1 - 8.5e-11 40.8 11.0 0.00025 20.2 0.8 3.9 3 0 0 3 3 3 3 SAMP Motif APC_15aa PF05972.11 PVD36214.1 - 8.7e-10 38.2 13.3 9.6e-05 22.4 0.5 4.5 4 0 0 4 4 4 3 APC 15 residue motif SRP19 PF01922.17 PVD36215.1 - 6.6e-11 43.0 0.1 1.4e-10 42.0 0.0 1.5 2 0 0 2 2 2 1 SRP19 protein DUF1248 PF06852.12 PVD36215.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1248) Peptidase_S8_N PF16361.5 PVD36216.1 - 0.027 15.0 1.3 0.59 10.6 0.0 2.8 2 1 0 2 2 2 0 N-terminal of Subtilase family FliJ PF02050.16 PVD36216.1 - 0.38 11.0 20.4 0.077 13.2 2.3 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 PVD36216.1 - 0.55 9.5 7.3 2.4 7.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PIN_12 PF16289.5 PVD36216.1 - 1.2 9.6 12.0 4.2 7.8 1.2 2.5 1 1 1 2 2 2 0 PIN domain Phage_Mu_Gam PF07352.12 PVD36216.1 - 4.7 7.1 12.4 1.5 8.7 1.4 2.7 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein ING PF12998.7 PVD36216.1 - 5.1 7.8 13.4 0.62 10.7 5.0 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding adh_short PF00106.25 PVD36218.1 - 2.2e-42 144.7 0.1 2.7e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD36218.1 - 7.4e-25 87.9 0.0 8.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD36218.1 - 3.2e-07 30.4 1.4 2.4e-06 27.6 1.4 2.0 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 PVD36218.1 - 0.001 18.5 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 PVD36218.1 - 0.002 17.6 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 PVD36218.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 PVD36218.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PVD36218.1 - 0.051 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EF-hand_6 PF13405.6 PVD36219.1 - 0.00015 21.4 0.1 0.082 12.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PVD36219.1 - 0.0003 21.2 0.3 0.017 15.5 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD36219.1 - 0.00091 18.6 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 EF hand His_Phos_2 PF00328.22 PVD36220.1 - 1.3e-11 44.4 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 PVD36223.1 - 2.1e-05 24.1 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Astro_capsid_p PF12226.8 PVD36223.1 - 3.1 6.8 8.0 3.5 6.7 8.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein His_Phos_2 PF00328.22 PVD36224.1 - 3.7e-25 89.1 0.1 1.1e-13 51.4 0.2 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3565 PF12088.8 PVD36224.1 - 0.016 15.2 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) Glycos_transf_2 PF00535.26 PVD36225.1 - 1.6e-27 96.3 0.1 2.8e-27 95.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PVD36225.1 - 3.1e-06 27.3 0.4 2.2e-05 24.5 0.4 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PVD36225.1 - 4.2e-06 26.3 0.0 9.4e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PVD36225.1 - 2.7e-05 23.8 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 PVD36225.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Peptidase_M76 PF09768.9 PVD36226.1 - 0.29 10.9 2.9 0.93 9.3 2.9 1.8 1 0 0 1 1 1 0 Peptidase M76 family DUF760 PF05542.11 PVD36226.1 - 4.6 7.7 5.9 4 7.9 1.7 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF760) WD40 PF00400.32 PVD36227.1 - 1.3e-22 79.6 27.7 0.013 16.3 0.0 10.8 11 0 0 11 11 11 8 WD domain, G-beta repeat HELP PF03451.14 PVD36227.1 - 3.4e-16 58.8 0.0 9.1e-16 57.5 0.0 1.7 2 0 0 2 2 2 1 HELP motif ANAPC4_WD40 PF12894.7 PVD36227.1 - 1.6e-07 31.5 0.4 0.0002 21.6 0.1 4.3 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 PVD36228.1 - 0.0029 17.1 0.0 0.0072 15.8 0.0 1.8 1 0 0 1 1 1 1 EF hand DUF1674 PF07896.12 PVD36228.1 - 0.017 15.6 0.8 0.017 15.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) Sel_put PF04328.13 PVD36228.1 - 0.019 15.0 0.3 0.049 13.7 0.3 1.7 1 0 0 1 1 1 0 Selenoprotein, putative EF-hand_7 PF13499.6 PVD36228.1 - 0.11 13.0 0.1 1.5 9.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair LPMO_10 PF03067.15 PVD36230.1 - 1.1e-10 42.6 0.3 1.1e-10 42.6 0.3 2.2 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading N2227 PF07942.12 PVD36231.1 - 1.1e-104 349.4 0.0 1.3e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 PVD36231.1 - 0.00061 19.7 0.0 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 PVD36231.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 PVD36231.1 - 0.0019 18.8 0.0 0.054 14.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD36231.1 - 0.024 15.4 0.0 0.098 13.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 PVD36231.1 - 0.08 13.6 0.0 4.2 8.1 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain TPMT PF05724.11 PVD36231.1 - 0.099 12.3 0.0 3.9 7.1 0.0 2.7 2 1 1 3 3 3 0 Thiopurine S-methyltransferase (TPMT) Snapin_Pallidin PF14712.6 PVD36232.1 - 2.1e-17 63.3 2.8 2.1e-17 63.3 2.8 1.7 2 0 0 2 2 2 1 Snapin/Pallidin KxDL PF10241.9 PVD36232.1 - 0.0074 16.5 2.0 0.0074 16.5 2.0 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein Proteasome PF00227.26 PVD36233.1 - 8.2e-32 110.2 0.0 1.1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Arm PF00514.23 PVD36234.1 - 2.6e-10 40.0 0.1 0.00063 19.7 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PVD36234.1 - 0.00011 22.6 0.0 0.14 12.7 0.0 2.7 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.22 PVD36234.1 - 0.004 17.3 0.2 4.6 7.8 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat V-ATPase_H_N PF03224.14 PVD36234.1 - 0.012 14.9 0.4 0.031 13.6 0.4 1.6 1 0 0 1 1 1 0 V-ATPase subunit H Cnd1 PF12717.7 PVD36234.1 - 0.013 15.5 0.6 0.037 14.1 0.0 2.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD36234.1 - 0.058 13.8 0.0 0.3 11.5 0.0 2.3 2 1 0 2 2 2 0 HEAT repeats Fz PF01392.22 PVD36235.1 - 1.9e-47 160.4 19.3 8.1e-24 84.4 5.8 2.1 2 0 0 2 2 2 2 Fz domain Lectin_C PF00059.21 PVD36236.1 - 6.8e-25 87.9 1.6 1.5e-09 38.5 0.1 3.3 3 0 0 3 3 3 3 Lectin C-type domain PAN_2 PF08276.11 PVD36236.1 - 0.0014 18.7 0.7 2.2 8.4 0.1 2.8 2 0 0 2 2 2 2 PAN-like domain Stealth_CR1 PF17101.5 PVD36236.1 - 0.0027 17.4 13.3 1.4 8.7 1.2 3.4 3 0 0 3 3 3 3 Stealth protein CR1, conserved region 1 Ribosomal_L37e PF01907.19 PVD36236.1 - 0.015 15.5 3.9 30 4.9 0.0 4.4 5 0 0 5 5 5 0 Ribosomal protein L37e PAN_4 PF14295.6 PVD36236.1 - 0.12 12.3 15.2 0.43 10.5 0.3 4.1 5 0 0 5 5 5 0 PAN domain PTS_EIIB PF00367.20 PVD36236.1 - 0.15 11.6 3.6 36 4.0 0.1 3.3 3 0 0 3 3 3 0 phosphotransferase system, EIIB Lectin_C PF00059.21 PVD36237.1 - 6.4e-19 68.7 0.2 8.4e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 Lectin C-type domain Stealth_CR1 PF17101.5 PVD36237.1 - 0.015 15.0 6.8 0.94 9.3 1.2 2.4 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 Ribosomal_L37e PF01907.19 PVD36237.1 - 0.34 11.1 3.6 23 5.3 0.0 3.7 4 0 0 4 4 4 0 Ribosomal protein L37e PAN_4 PF14295.6 PVD36237.1 - 0.42 10.5 4.8 0.28 11.1 0.3 2.8 3 0 0 3 3 3 0 PAN domain PTS_EIIB PF00367.20 PVD36237.1 - 0.44 10.1 1.2 24 4.5 0.1 2.4 2 0 0 2 2 2 0 phosphotransferase system, EIIB Lectin_C PF00059.21 PVD36238.1 - 7.3e-07 29.9 15.9 4.1e-06 27.5 0.0 5.1 5 0 0 5 5 5 1 Lectin C-type domain Defensin_big PF14862.6 PVD36238.1 - 0.024 15.0 16.9 3.7 7.9 0.1 4.7 4 0 0 4 4 4 0 Big defensin Stealth_CR1 PF17101.5 PVD36238.1 - 0.15 11.8 2.6 0.32 10.7 2.6 1.6 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 Sugar_tr PF00083.24 PVD36239.1 - 1.4e-119 399.9 10.1 1.8e-119 399.6 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD36239.1 - 3e-21 75.7 17.9 4.3e-21 75.2 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gly-zipper_YMGG PF13441.6 PVD36239.1 - 0.61 9.9 7.2 1.4 8.7 7.2 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 PVD36239.1 - 1.6 8.7 8.6 4 7.4 8.6 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain O-FucT PF10250.9 PVD36241.1 - 0.0005 19.9 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 PVD36242.1 - 0.01 15.1 0.0 4.3 6.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 11 EF-hand_1 PF00036.32 PVD36243.1 - 2.3e-11 42.4 7.8 0.00029 20.2 0.2 4.4 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 PVD36243.1 - 1.6e-10 40.0 2.4 0.0052 16.2 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PVD36243.1 - 1.5e-09 37.0 8.2 6.2e-06 25.7 0.1 4.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 PVD36243.1 - 5e-09 36.5 3.7 3.7e-06 27.3 0.3 2.9 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PVD36243.1 - 0.00023 20.9 5.8 3.6 7.5 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD36243.1 - 0.0036 17.6 2.1 0.31 11.3 0.1 2.9 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PVD36243.1 - 0.031 14.5 0.0 5.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I domain Spermine_synth PF01564.17 PVD36244.1 - 7.9e-20 71.1 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain zf-H2C2_2 PF13465.6 PVD36244.1 - 6.9e-10 38.9 23.3 2.1e-06 27.9 2.4 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD36244.1 - 5.4e-08 33.0 14.8 0.015 16.1 1.9 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger Spermine_synt_N PF17284.2 PVD36244.1 - 7.2e-08 32.2 0.1 1.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain zf-C2H2 PF00096.26 PVD36244.1 - 4.9e-06 26.7 22.7 7.2e-05 23.0 1.6 4.4 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 PVD36244.1 - 0.07 13.5 6.6 0.85 10.0 0.5 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 PVD36244.1 - 0.14 12.1 2.2 3.7 7.5 0.9 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-met PF12874.7 PVD36244.1 - 0.64 10.5 12.2 0.77 10.2 0.9 4.2 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD36244.1 - 1.2 9.6 17.3 1.1 9.7 0.2 5.1 5 1 2 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PVD36244.1 - 1.2 9.5 7.2 0.11 12.8 1.8 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ependymin PF00811.18 PVD36245.1 - 4.7e-07 30.1 0.1 8.5e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Ependymin zinc_ribbon_5 PF13719.6 PVD36246.1 - 0.016 15.0 0.0 0.054 13.3 0.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Orf78 PF06024.12 PVD36246.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) LSM PF01423.22 PVD36247.1 - 1.8e-20 72.4 0.0 2.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 PVD36247.1 - 0.097 12.8 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain ABC_membrane PF00664.23 PVD36248.1 - 9.4e-65 219.0 36.1 6.2e-37 127.7 11.8 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD36248.1 - 3.1e-51 173.5 0.8 1.7e-27 96.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 PVD36248.1 - 9.3e-10 38.3 1.2 0.0017 17.9 0.0 4.6 2 2 2 5 5 5 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD36248.1 - 1.9e-06 27.9 0.1 0.032 14.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PVD36248.1 - 3e-05 24.5 0.2 1.1 9.6 0.1 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PVD36248.1 - 0.00015 21.4 1.6 0.41 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD36248.1 - 0.00042 20.2 0.1 3 7.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PVD36248.1 - 0.00094 19.1 0.4 2 8.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 PVD36248.1 - 0.0036 16.3 0.5 0.77 8.7 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF5090 PF17009.5 PVD36248.1 - 0.0043 17.0 5.7 0.0043 17.0 5.7 3.1 4 0 0 4 4 2 1 Domain of unknown function (DUF5090) ABC_membrane_3 PF13748.6 PVD36248.1 - 0.015 14.5 3.4 0.03 13.6 2.2 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_24 PF13479.6 PVD36248.1 - 0.016 14.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PVD36248.1 - 0.017 14.1 0.7 4.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 PVD36248.1 - 0.017 14.4 0.2 1.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 PVD36248.1 - 0.053 13.8 3.4 4.7 7.5 0.4 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PVD36248.1 - 0.073 13.1 5.9 0.65 10.0 0.5 3.2 3 0 0 3 3 3 0 Dynamin family AAA_18 PF13238.6 PVD36248.1 - 0.077 13.5 0.0 24 5.5 0.0 3.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PVD36248.1 - 0.1 11.8 0.8 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PVD36248.1 - 0.1 12.1 1.1 7 6.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 PVD36248.1 - 0.15 11.8 1.4 22 4.7 0.1 3.1 3 0 0 3 3 3 0 AAA domain NIL PF09383.10 PVD36248.1 - 0.16 11.8 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 1 0 NIL domain Roc PF08477.13 PVD36248.1 - 1 9.6 4.6 30 4.8 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 PVD36248.1 - 5.4 7.5 10.2 4.5 7.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF3671 PF12420.8 PVD36248.1 - 6 7.0 8.9 5.1 7.2 3.1 3.7 3 0 0 3 3 3 0 Protein of unknown function Baculo_LEF-3 PF05847.11 PVD36249.1 - 0.036 13.3 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) CTD PF12815.7 PVD36255.1 - 1.2 9.8 33.7 0.71 10.5 25.8 3.8 3 1 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 FeoB_C PF07664.12 PVD36256.1 - 0.89 9.3 4.3 0.34 10.6 0.7 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus ERAP1_C PF11838.8 PVD36257.1 - 4.8e-54 184.0 0.5 1.8e-31 109.9 0.2 2.4 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD36257.1 - 3.4e-46 157.5 5.4 1.1e-45 155.9 4.3 2.0 1 1 1 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD36257.1 - 1.9e-25 90.1 0.0 3.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 PVD36258.1 - 8.6e-82 275.2 9.4 3.6e-80 269.9 3.5 2.6 3 0 0 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD36258.1 - 5.5e-77 258.2 0.9 1.1e-76 257.3 0.9 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD36258.1 - 4.8e-39 134.5 0.4 1.1e-28 100.7 0.1 2.7 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain LRR_6 PF13516.6 PVD36260.1 - 3.1e-14 51.8 18.0 9.6e-06 25.3 0.5 5.0 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 PVD36260.1 - 3.3 8.3 17.0 0.88 10.1 3.8 4.4 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Thioredoxin PF00085.20 PVD36261.1 - 8.8e-11 41.7 0.0 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PVD36261.1 - 5.8e-05 23.1 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 PVD36261.1 - 7.5e-05 22.7 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 PVD36261.1 - 0.0013 18.6 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein DUF836 PF05768.14 PVD36261.1 - 0.0017 18.7 0.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 PVD36261.1 - 0.05 12.9 0.7 0.11 11.8 0.1 2.0 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family PEX11 PF05648.14 PVD36262.1 - 2e-36 125.5 0.3 2.3e-36 125.4 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CBM_14 PF01607.24 PVD36264.1 - 2.5e-11 43.6 22.1 2.9e-06 27.3 5.8 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.27 PVD36265.1 - 1.3e-37 129.8 0.0 7.8e-37 127.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD36265.1 - 1.2e-06 29.1 0.0 3.7e-06 27.5 0.0 1.7 1 1 1 2 2 2 1 Sulfotransferase family Ion_trans PF00520.31 PVD36266.1 - 8.8e-25 87.4 18.7 2.2e-24 86.0 18.6 1.7 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 PVD36266.1 - 1e-23 83.5 0.0 2.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 PVD36266.1 - 6.8e-10 38.8 13.4 6.8e-10 38.8 13.4 1.7 2 0 0 2 2 2 1 Ion channel TauE PF01925.19 PVD36266.1 - 0.033 13.8 5.1 0.059 13.0 5.1 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF979 PF06166.12 PVD36266.1 - 0.059 12.5 3.5 0.11 11.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF979) S1FA PF04689.13 PVD36266.1 - 0.1 12.8 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 DNA binding protein S1FA zf-C2H2 PF00096.26 PVD36267.1 - 5.2e-10 39.2 1.8 6.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD36267.1 - 9.1e-07 29.0 0.5 9.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD36267.1 - 3.4e-06 27.4 2.0 0.0024 18.6 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 PVD36267.1 - 0.0029 17.6 0.3 0.0069 16.4 0.2 1.7 1 1 0 1 1 1 1 BED zinc finger zf-C2H2_11 PF16622.5 PVD36267.1 - 0.088 12.6 0.3 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 PVD36267.1 - 6.9 6.5 9.1 2.8 7.8 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ank_2 PF12796.7 PVD36268.1 - 3.1e-190 617.3 69.4 1.3e-18 67.4 0.6 14.7 3 2 13 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.30 PVD36268.1 - 2.6e-159 511.5 58.0 2.6e-06 27.6 0.1 30.6 30 1 0 30 30 30 28 Ankyrin repeat Ank_4 PF13637.6 PVD36268.1 - 3.4e-149 483.5 37.5 8e-12 45.4 0.1 21.7 11 7 12 23 23 23 22 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD36268.1 - 9.1e-129 417.8 42.7 5.4e-11 42.5 0.1 21.3 7 3 17 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD36268.1 - 1e-125 394.2 42.9 2.3e-05 24.4 0.0 30.1 30 0 0 30 30 30 27 Ankyrin repeat ZU5 PF00791.20 PVD36268.1 - 1.9e-07 31.3 0.0 8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 ZU5 domain ArlS_N PF18719.1 PVD36268.1 - 0.059 13.6 0.0 30 4.8 0.0 4.3 4 1 0 4 4 4 0 ArlS sensor domain DUF4746 PF15928.5 PVD36268.1 - 4.1 6.7 7.9 0.78 9.1 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Ank_2 PF12796.7 PVD36269.1 - 5.3e-177 574.9 47.0 1.5e-17 64.0 0.1 15.2 3 3 10 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.30 PVD36269.1 - 2.2e-154 495.9 64.4 3.9e-08 33.4 0.4 30.9 31 0 0 31 31 31 28 Ankyrin repeat Ank_4 PF13637.6 PVD36269.1 - 2.3e-143 464.9 50.4 5.5e-11 42.8 0.1 23.4 8 5 18 26 26 26 25 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD36269.1 - 2.8e-128 402.1 60.2 6.3e-06 26.2 0.0 32.3 33 0 0 33 33 33 28 Ankyrin repeat Ank_5 PF13857.6 PVD36269.1 - 5e-120 390.0 53.0 2.3e-09 37.3 0.1 22.9 4 4 19 25 25 25 24 Ankyrin repeats (many copies) ZU5 PF00791.20 PVD36269.1 - 9.7e-07 29.1 0.0 3.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain Phospholip_A2_2 PF05826.12 PVD36269.1 - 0.36 11.1 1.9 30 4.9 0.7 2.8 2 0 0 2 2 2 0 Phospholipase A2 Beta-lactamase PF00144.24 PVD36270.1 - 6.4e-51 173.5 0.0 1.6e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 PVD36270.1 - 0.0017 17.8 0.2 0.05 13.0 0.1 2.2 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase WD40 PF00400.32 PVD36271.1 - 6.2e-38 128.1 8.8 3.3e-07 30.9 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36271.1 - 1.8e-17 63.4 0.2 1.8e-05 24.9 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 PVD36271.1 - 2.9e-14 52.4 0.4 5.5e-14 51.5 0.4 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 PVD36271.1 - 4.2e-11 42.4 1.6 0.01 14.8 0.0 3.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PVD36271.1 - 2.9e-08 32.8 0.0 0.026 13.2 0.0 3.5 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.11 PVD36271.1 - 0.0011 18.7 2.3 24 4.5 0.0 4.6 5 0 0 5 5 5 1 TUP1-like enhancer of split WD40_like PF17005.5 PVD36271.1 - 0.028 13.7 0.2 0.14 11.5 0.2 2.2 1 1 0 1 1 1 0 WD40-like domain LRR_4 PF12799.7 PVD36272.1 - 2.8e-20 72.0 14.4 7e-11 42.2 0.2 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD36272.1 - 2.1e-17 63.2 0.3 2.9e-17 62.7 0.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PVD36272.1 - 7.5e-15 54.4 21.7 7.1e-08 32.1 2.2 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 PVD36272.1 - 6.8e-07 28.8 9.3 0.022 14.8 0.0 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 PVD36272.1 - 0.00015 21.9 7.4 1.2 10.0 0.1 4.6 4 1 0 4 4 4 1 Leucine Rich Repeat ARTD15_N PF18084.1 PVD36272.1 - 0.044 14.0 0.3 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 ARTD15 N-terminal domain LRR_2 PF07723.13 PVD36272.1 - 0.11 13.2 3.6 12 6.7 0.2 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat Clat_adaptor_s PF01217.20 PVD36273.1 - 1.6e-51 173.9 2.5 2.1e-51 173.6 2.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.22 PVD36274.1 - 1.5e-52 177.4 0.0 1.9e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD36274.1 - 6.5e-31 107.0 0.0 9.1e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36274.1 - 3.7e-11 42.8 0.0 6.1e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD36274.1 - 0.00035 20.5 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD36274.1 - 0.0029 17.2 0.0 0.0058 16.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD36274.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPP_enzyme_M PF00205.22 PVD36274.1 - 0.044 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AAA_24 PF13479.6 PVD36274.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MH2 PF03166.14 PVD36275.1 - 6.5e-74 248.2 0.0 9.1e-74 247.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 PVD36275.1 - 6.1e-40 135.6 0.2 1.1e-39 134.8 0.2 1.4 1 0 0 1 1 1 1 MH1 domain zf-C2H2_4 PF13894.6 PVD36276.1 - 7e-13 48.2 15.3 0.00018 22.0 1.7 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD36276.1 - 1.6e-10 40.9 15.4 0.003 17.9 2.8 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type HALZ PF02183.18 PVD36276.1 - 8.2e-05 22.7 26.9 0.039 14.2 2.0 4.8 1 1 3 4 4 4 4 Homeobox associated leucine zipper zf-C2H2_6 PF13912.6 PVD36276.1 - 0.00036 20.5 5.8 0.0017 18.3 2.0 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger APG6_N PF17675.1 PVD36276.1 - 0.0026 18.3 35.9 0.029 14.9 9.2 3.3 2 2 1 3 3 3 2 Apg6 coiled-coil region zf-C2H2_11 PF16622.5 PVD36276.1 - 0.0079 15.9 11.9 0.62 9.9 0.2 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 PVD36276.1 - 0.01 15.7 4.9 0.83 9.5 0.2 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 PVD36276.1 - 0.013 15.8 10.0 0.036 14.4 3.1 2.9 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 PVD36276.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.8 3 0 0 3 3 3 0 Zinc ribbon domain DivIC PF04977.15 PVD36276.1 - 0.077 12.8 23.2 0.097 12.5 1.2 3.6 1 1 2 3 3 3 0 Septum formation initiator LIM PF00412.22 PVD36276.1 - 0.11 12.8 4.6 5.7 7.2 5.8 2.9 1 1 1 2 2 2 0 LIM domain zf-nanos PF05741.13 PVD36276.1 - 0.22 11.8 6.6 0.19 11.9 0.8 3.1 3 0 0 3 3 3 0 Nanos RNA binding domain zf-C2H2_8 PF15909.5 PVD36276.1 - 0.38 11.1 6.2 0.45 10.8 0.7 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon Spc7 PF08317.11 PVD36276.1 - 0.75 8.6 21.3 0.95 8.3 20.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 PVD36276.1 - 0.79 9.0 14.8 1.7 7.9 7.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zinc-ribbons_6 PF07191.12 PVD36276.1 - 1.3 9.1 10.7 3.2 7.8 3.7 3.3 2 1 1 3 3 3 0 zinc-ribbons NOB1_Zn_bind PF08772.11 PVD36276.1 - 1.6 9.0 5.7 0.33 11.2 0.5 2.5 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-met PF12874.7 PVD36276.1 - 1.6 9.3 16.8 0.74 10.3 1.9 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 PVD36276.1 - 6.4 7.4 22.2 5.2 7.7 1.3 5.4 6 0 0 6 6 6 0 Zinc-finger double domain PPO1_DWL PF12142.8 PVD36277.1 - 0.12 12.2 2.7 2.3e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Polyphenol oxidase middle domain Lectin_C PF00059.21 PVD36278.1 - 2.3e-14 54.0 3.2 3.4e-14 53.5 3.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD36278.1 - 1.3e-05 25.0 0.9 3.8e-05 23.4 0.9 1.7 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Leo1 PF04004.13 PVD36279.1 - 6.4e-53 179.0 0.1 6.4e-53 179.0 0.1 2.1 2 0 0 2 2 2 1 Leo1-like protein VEFS-Box PF09733.9 PVD36279.1 - 7.8 6.3 9.7 2.1 8.1 6.1 1.9 1 1 1 2 2 2 0 VEFS-Box of polycomb protein PDZ PF00595.24 PVD36280.1 - 3e-46 155.6 4.0 1.1e-16 60.9 0.2 3.6 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 PVD36280.1 - 6.6e-35 119.4 0.0 1.7e-34 118.1 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 PVD36280.1 - 6.3e-28 96.4 7.0 3.5e-10 39.6 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PVD36280.1 - 1.9e-14 53.7 0.5 3e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 PVD36280.1 - 3.2e-10 40.0 0.0 2.3e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 PVD36280.1 - 0.21 11.3 1.5 0.34 10.6 0.2 2.1 2 0 0 2 2 2 0 Variant SH3 domain DUF4140 PF13600.6 PVD36280.1 - 0.28 11.7 1.9 2.4 8.7 0.5 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MAD PF05557.13 PVD36280.1 - 1.1 7.6 4.5 0.12 10.7 0.1 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein Pepsin-I3 PF06394.13 PVD36282.1 - 0.0028 17.8 0.2 3.2 8.0 0.0 3.0 3 0 0 3 3 3 2 Pepsin inhibitor-3-like repeated domain UPF0506 PF11703.8 PVD36282.1 - 0.0086 16.4 22.7 0.31 11.4 7.7 2.6 2 0 0 2 2 2 2 UPF0506 fn3_2 PF16893.5 PVD36282.1 - 0.085 13.0 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Fibronectin type III domain Tat PF00539.18 PVD36285.1 - 0.016 15.4 0.6 0.034 14.3 0.6 1.5 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) PH_9 PF15410.6 PVD36285.1 - 0.055 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2_6 PF13912.6 PVD36286.1 - 0.39 10.8 5.7 11 6.2 0.4 3.8 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.7 PVD36286.1 - 3.4 7.8 42.6 2 8.5 0.5 6.2 5 1 0 5 5 5 0 Double zinc ribbon DZR PF12773.7 PVD36287.1 - 0.0015 18.5 8.2 0.25 11.4 0.4 2.6 2 0 0 2 2 2 2 Double zinc ribbon Rpr2 PF04032.16 PVD36287.1 - 0.002 18.4 0.4 0.002 18.4 0.4 2.8 2 1 0 2 2 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.6 PVD36287.1 - 0.0039 17.9 0.1 0.0039 17.9 0.1 4.3 3 1 1 4 4 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD36287.1 - 0.0095 16.3 2.0 0.0095 16.3 2.0 3.5 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36287.1 - 0.1 13.1 0.1 0.1 13.1 0.1 4.1 4 1 0 4 4 3 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.6 PVD36287.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.7 3 1 1 4 4 4 0 Nudix N-terminal DUF2321 PF10083.9 PVD36287.1 - 0.38 10.4 3.0 2.6 7.6 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_jaz PF12171.8 PVD36287.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.3 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 PVD36287.1 - 0.53 10.6 8.1 37 4.7 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon XPA_N PF01286.18 PVD36287.1 - 0.55 10.3 9.3 2.1 8.5 0.1 3.9 4 0 0 4 4 4 0 XPA protein N-terminal ADK_lid PF05191.14 PVD36287.1 - 0.95 9.5 6.5 0.88 9.6 0.3 3.1 2 1 1 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 PVD36287.1 - 5.4 7.2 10.7 0.71 10.0 0.9 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zf-trcl PF13451.6 PVD36287.1 - 5.7 6.9 11.1 3.3 7.7 2.4 3.8 3 1 0 3 3 3 0 Probable zinc-ribbon domain FYVE PF01363.21 PVD36287.1 - 8.8 6.6 10.3 5.6 7.2 2.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger LRR_6 PF13516.6 PVD36288.1 - 4.3e-07 29.5 5.0 0.55 10.4 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich repeat FIVAR PF07554.13 PVD36288.1 - 0.089 13.6 2.8 0.26 12.1 2.8 1.8 1 0 0 1 1 1 0 FIVAR domain Ras PF00071.22 PVD36289.1 - 3.3e-24 85.3 0.3 7.4e-20 71.2 0.1 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PVD36289.1 - 7.4e-17 61.7 0.1 8.6e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PVD36289.1 - 0.00039 20.5 0.2 0.00045 20.3 0.2 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 PVD36289.1 - 0.0083 15.6 0.0 0.014 14.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 PVD36289.1 - 0.0094 16.5 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PVD36289.1 - 0.011 16.1 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 PVD36289.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 PVD36289.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD36289.1 - 0.014 15.6 0.0 0.017 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 PVD36289.1 - 0.015 14.6 0.1 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 PVD36289.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 PVD36289.1 - 0.021 14.6 0.0 0.025 14.3 0.0 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 PVD36289.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.3 1 1 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 PVD36289.1 - 0.031 13.7 0.1 0.058 12.8 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PRK PF00485.18 PVD36289.1 - 0.032 14.0 0.1 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 PVD36289.1 - 0.057 13.4 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 PVD36289.1 - 0.061 13.2 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 PVD36289.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 PVD36289.1 - 0.1 11.9 0.0 11 5.2 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin MCM PF00493.23 PVD36289.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_28 PF13521.6 PVD36289.1 - 0.16 12.2 0.0 0.63 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain UPF0560 PF10577.9 PVD36291.1 - 0.13 10.8 0.6 0.15 10.6 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 YjeF_N PF03853.15 PVD36292.1 - 3.3e-33 115.0 0.0 4.2e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Macscav_rec PF03523.13 PVD36292.1 - 0.36 10.8 1.2 0.75 9.7 0.4 1.8 2 0 0 2 2 2 0 Macrophage scavenger receptor HD_4 PF13328.6 PVD36293.1 - 3.4e-15 56.1 1.1 7.9e-15 54.9 1.1 1.5 1 1 0 1 1 1 1 HD domain HD PF01966.22 PVD36293.1 - 0.0034 17.6 0.4 0.011 16.0 0.4 1.7 1 1 0 1 1 1 1 HD domain SAM_PNT PF02198.16 PVD36293.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain LEDGF PF11467.8 PVD36294.1 - 6.6e-26 90.3 7.7 6.6e-26 90.3 7.7 2.5 2 0 0 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) Peptidase_A2B PF12384.8 PVD36294.1 - 0.031 13.8 0.0 0.084 12.4 0.0 1.7 2 0 0 2 2 2 0 Ty3 transposon peptidase PWWP PF00855.17 PVD36294.1 - 0.7 10.3 0.0 0.7 10.3 0.0 4.6 4 0 0 4 4 4 0 PWWP domain EMP24_GP25L PF01105.24 PVD36295.1 - 3.1e-41 141.3 0.2 3.8e-41 141.0 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DnaJ_C PF01556.18 PVD36296.1 - 2.9e-44 150.7 1.0 3.8e-44 150.3 1.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PVD36296.1 - 1.6e-28 98.6 1.6 3.1e-28 97.7 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PVD36296.1 - 1.4e-13 51.0 19.1 2.4e-13 50.2 19.1 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 PVD36296.1 - 0.18 11.6 0.2 0.18 11.6 0.2 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain HypA PF01155.19 PVD36296.1 - 0.32 11.0 7.9 5 7.2 2.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 PVD36296.1 - 0.61 10.1 11.7 3.2 7.8 2.4 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RseC_MucC PF04246.12 PVD36296.1 - 2.7 8.0 6.6 0.24 11.4 1.1 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Flavokinase PF01687.17 PVD36297.1 - 1.3e-27 96.3 0.0 1.5e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase KIAA1328 PF15369.6 PVD36298.1 - 1.7e-17 64.3 34.9 1.7e-16 61.0 20.1 4.2 5 0 0 5 5 5 2 Uncharacterised protein KIAA1328 RNase_T PF00929.24 PVD36299.1 - 2.3e-11 44.5 0.0 4.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 PVD36299.1 - 8.5e-06 25.6 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease DUF465 PF04325.13 PVD36299.1 - 3.6 7.7 8.7 1.3 9.1 3.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF465) Hydrolase_6 PF13344.6 PVD36300.1 - 7.7e-17 61.3 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PVD36300.1 - 5.4e-06 26.6 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD36300.1 - 3.8e-05 24.1 0.1 0.00081 19.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PVD36300.1 - 0.00033 20.7 0.0 0.00079 19.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_phosphat_B PF03767.14 PVD36300.1 - 0.038 13.6 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PRP3 PF08572.10 PVD36301.1 - 2.4e-75 253.1 8.2 2.4e-75 253.1 8.2 2.5 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 PVD36301.1 - 4.4e-15 56.0 0.5 3.2e-13 50.0 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PWI PF01480.17 PVD36301.1 - 0.00073 19.8 0.0 0.0023 18.2 0.0 1.9 1 0 0 1 1 1 1 PWI domain Annexin_like PF18411.1 PVD36301.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Annexin-like domain Ig_3 PF13927.6 PVD36302.1 - 4.6e-34 116.9 0.0 1.1e-11 45.1 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD36302.1 - 5.2e-33 113.0 0.0 9e-14 51.3 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36302.1 - 2.3e-24 85.5 0.0 1.7e-06 28.2 0.0 4.0 2 1 2 4 4 4 3 Immunoglobulin domain fn3 PF00041.21 PVD36302.1 - 9.1e-22 77.2 0.8 5.2e-12 45.9 0.2 2.6 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 PVD36302.1 - 2.5e-20 72.4 0.0 4e-07 30.1 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD36302.1 - 3.5e-13 49.7 1.7 0.00093 19.3 0.0 6.0 4 2 0 4 4 4 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 PVD36302.1 - 9.9e-05 22.8 0.2 0.002 18.6 0.1 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 PVD36302.1 - 0.00029 20.9 0.0 0.1 12.7 0.0 3.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD36302.1 - 0.0016 18.0 0.0 0.82 9.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 PVD36302.1 - 0.0039 16.9 11.5 0.0079 15.9 11.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Ig_4 PF16680.5 PVD36302.1 - 0.09 13.1 0.2 2.1 8.6 0.0 3.2 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD36302.1 - 0.11 12.6 0.2 5 7.3 0.0 3.2 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain zf-H2C2_2 PF13465.6 PVD36303.1 - 6.2e-08 32.7 0.9 6.2e-08 32.7 0.9 5.1 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36303.1 - 1.1e-06 28.7 19.2 0.0031 17.9 0.5 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36303.1 - 0.0024 18.6 14.0 0.22 12.4 0.5 5.4 4 0 0 4 4 4 2 C2H2-type zinc finger DZR PF12773.7 PVD36303.1 - 0.0073 16.3 18.4 0.083 12.9 1.1 4.3 4 0 0 4 4 4 2 Double zinc ribbon zf-C2H2_8 PF15909.5 PVD36303.1 - 0.035 14.4 3.3 0.13 12.6 0.3 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 PVD36303.1 - 0.5 10.2 12.4 4.6 7.1 0.0 5.3 6 0 0 6 6 6 0 zinc-finger C2H2-type RNA_POL_M_15KD PF02150.16 PVD36303.1 - 0.55 10.2 8.0 0.25 11.3 0.7 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 PVD36303.1 - 3 7.5 11.8 5.8 6.6 0.1 4.2 4 1 1 5 5 5 0 Ubiquitin-Binding Zinc Finger Mito_fiss_reg PF05308.11 PVD36303.1 - 3.2 7.7 7.9 7.9 6.5 7.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PVD36303.1 - 5.2 6.5 10.7 9.2 5.6 10.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-H2C2_2 PF13465.6 PVD36304.1 - 3.7e-82 267.4 91.9 5.8e-09 36.0 1.3 17.4 17 0 0 17 17 17 14 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36304.1 - 2.4e-56 185.2 102.8 2e-05 24.8 0.6 16.4 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36304.1 - 8.3e-44 144.5 112.4 0.00055 20.5 1.4 16.6 17 0 0 17 17 16 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD36304.1 - 7.7e-16 57.9 64.7 0.12 12.7 0.4 15.7 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD36304.1 - 3.5e-07 29.8 90.3 0.0015 18.2 0.0 15.1 16 0 0 16 16 15 6 zinc-finger C2H2-type zf-met PF12874.7 PVD36304.1 - 3.9e-06 27.1 85.3 0.003 17.9 0.9 14.0 15 0 0 15 15 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD36304.1 - 5e-06 26.4 119.2 0.0012 18.8 2.5 16.3 16 1 0 16 16 15 8 C2H2-type zinc finger zf-C2HE PF16278.5 PVD36304.1 - 0.00021 21.7 84.7 0.013 15.9 0.7 14.4 5 2 10 15 15 14 3 C2HE / C2H2 / C2HC zinc-binding finger AT_hook PF02178.19 PVD36304.1 - 0.0037 16.9 9.1 0.38 10.8 3.7 3.7 3 0 0 3 3 3 1 AT hook motif zf-H2C2_5 PF13909.6 PVD36304.1 - 0.01 15.6 0.6 0.01 15.6 0.6 15.3 15 3 0 15 15 15 0 C2H2-type zinc-finger domain GAGA PF09237.11 PVD36304.1 - 0.026 14.3 17.6 2.2 8.1 0.0 7.5 3 2 5 8 8 8 0 GAGA factor DUF3268 PF11672.8 PVD36304.1 - 0.048 14.0 41.7 1.3 9.3 1.3 7.3 7 1 1 8 8 8 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 PVD36304.1 - 0.22 11.9 75.8 0.79 10.1 0.1 12.3 2 2 9 11 11 11 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 PVD36304.1 - 0.53 10.6 7.9 4.4 7.7 0.0 4.5 5 0 0 5 5 5 0 BolA-like protein zf-FPG_IleRS PF06827.14 PVD36304.1 - 1.1 9.2 0.0 1.1 9.2 0.0 6.5 9 0 0 9 9 6 0 Zinc finger found in FPG and IleRS zf-C2HC_2 PF13913.6 PVD36304.1 - 1.3 9.0 34.1 2.4 8.2 0.3 9.7 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PVD36305.1 - 7.4e-05 23.0 0.3 7.4e-05 23.0 0.3 3.7 3 1 1 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36305.1 - 0.00065 20.3 0.3 0.00065 20.3 0.3 3.6 3 1 1 4 4 4 1 C2H2-type zinc finger DZR PF12773.7 PVD36305.1 - 0.0096 15.9 8.4 0.32 11.0 1.6 2.7 2 0 0 2 2 2 2 Double zinc ribbon zf-Di19 PF05605.12 PVD36305.1 - 0.09 13.1 0.4 0.09 13.1 0.4 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.12 PVD36305.1 - 0.094 13.2 11.2 0.4 11.2 0.2 2.9 3 0 0 3 3 3 0 CHY zinc finger zf-B_box PF00643.24 PVD36305.1 - 0.12 12.5 15.6 0.11 12.6 3.7 2.6 3 0 0 3 3 3 0 B-box zinc finger zf-C2H2_11 PF16622.5 PVD36305.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.6 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PVD36305.1 - 0.19 12.1 0.4 0.19 12.1 0.4 2.8 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD36305.1 - 0.55 10.3 4.1 0.24 11.4 0.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Mss51 PF13824.6 PVD36305.1 - 1.4 9.1 6.9 1.3 9.2 2.4 2.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Reprolysin_2 PF13574.6 PVD36306.1 - 1.5e-30 106.6 0.6 1.5e-30 106.6 0.6 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD36306.1 - 9.1e-23 81.4 0.7 9.1e-23 81.4 0.7 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD36306.1 - 1.1e-16 61.5 1.2 2.4e-16 60.4 0.6 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD36306.1 - 1.4e-10 41.1 0.9 1.8e-09 37.6 0.7 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD36306.1 - 6.9e-08 33.2 26.6 6.9e-08 33.2 26.6 4.0 3 1 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.19 PVD36306.1 - 0.043 14.0 0.4 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Reprolysin family propeptide DUF5350 PF17299.2 PVD36306.1 - 0.22 12.0 2.5 0.74 10.3 2.5 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5350) ODC_AZ PF02100.17 PVD36307.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Hexapep PF00132.24 PVD36308.1 - 1.3e-09 37.3 19.9 2.5e-05 23.8 1.0 4.9 3 2 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DctM PF06808.12 PVD36308.1 - 0.13 11.1 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Hexapep_2 PF14602.6 PVD36308.1 - 4 7.3 12.1 1.7 8.5 0.7 3.5 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase zf-RING_UBOX PF13445.6 PVD36309.1 - 1.6e-08 34.4 9.9 1.6e-08 34.4 9.9 3.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36309.1 - 2.9e-08 33.4 7.7 2.9e-08 33.4 7.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36309.1 - 1e-07 31.7 37.1 3.5e-07 30.0 11.8 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36309.1 - 7e-07 29.0 5.4 7e-07 29.0 5.4 3.7 3 2 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36309.1 - 5e-06 26.3 13.0 5e-06 26.3 13.0 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36309.1 - 5.2e-06 26.5 18.3 0.00041 20.4 3.1 4.6 5 0 0 5 5 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD36309.1 - 1.5e-05 25.3 12.9 1.5e-05 25.3 12.9 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36309.1 - 2e-05 24.6 8.3 2e-05 24.6 8.3 3.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36309.1 - 0.00052 19.9 9.4 0.00052 19.9 9.4 4.0 3 2 1 4 4 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PVD36309.1 - 0.013 15.6 7.6 0.013 15.6 7.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 PVD36309.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 U-box domain Hjc PF01870.18 PVD36309.1 - 0.13 12.3 0.1 8.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Ribosomal_S30AE PF02482.19 PVD36309.1 - 0.14 13.0 1.6 0.36 11.6 0.7 2.2 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Aminotran_1_2 PF00155.21 PVD36309.1 - 0.15 11.2 0.6 0.34 10.0 0.3 1.6 1 1 1 2 2 2 0 Aminotransferase class I and II NPV_P10 PF05531.12 PVD36309.1 - 0.38 11.2 1.8 3 8.4 0.2 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1456 PF07308.13 PVD36309.1 - 0.42 11.0 1.8 79 3.7 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) Apolipoprotein PF01442.18 PVD36309.1 - 1 9.2 8.8 3.2 7.6 8.6 1.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Rad50_zn_hook PF04423.14 PVD36309.1 - 2.4 8.1 0.0 2.4 8.1 0.0 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF1664 PF07889.12 PVD36309.1 - 3.1 7.9 6.1 2.2 8.3 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 PVD36309.1 - 3.2 7.3 7.7 2 8.0 2.9 2.6 1 1 1 2 2 2 0 fzo-like conserved region Kringle PF00051.18 PVD36310.1 - 2e-21 76.1 15.7 7.6e-12 45.4 2.3 4.3 6 0 0 6 6 6 2 Kringle domain Big_11 PF18200.1 PVD36310.1 - 0.087 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Kringle PF00051.18 PVD36311.1 - 3.1e-11 43.4 1.0 7.1e-11 42.3 1.0 1.6 1 0 0 1 1 1 1 Kringle domain Sushi PF00084.20 PVD36311.1 - 4.7e-10 39.9 7.5 1.1e-06 29.1 2.5 2.9 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) HRM PF02793.22 PVD36311.1 - 0.026 14.8 5.5 0.069 13.5 1.3 2.7 3 0 0 3 3 3 0 Hormone receptor domain Sushi PF00084.20 PVD36312.1 - 1.6e-10 41.4 8.5 4.1e-07 30.5 0.1 3.8 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Kringle PF00051.18 PVD36312.1 - 9.2e-06 25.9 2.5 2.3e-05 24.6 2.5 1.7 1 0 0 1 1 1 1 Kringle domain zf-H2C2_2 PF13465.6 PVD36313.1 - 4.6e-35 118.5 150.7 1.1e-09 38.2 0.4 19.1 21 1 1 22 22 22 10 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36313.1 - 9.3e-31 104.6 179.0 2.8e-05 24.3 0.2 19.2 19 0 0 19 19 19 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36313.1 - 2.5e-29 99.4 168.3 0.0019 18.8 0.2 18.7 18 0 0 18 18 18 16 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD36313.1 - 1.3e-05 25.1 145.0 0.0041 17.1 4.1 17.3 18 0 0 18 18 18 9 C2H2-type zinc finger TerY_C PF15616.6 PVD36313.1 - 0.45 10.6 18.8 1.7 8.8 0.9 4.2 3 0 0 3 3 3 0 TerY-C metal binding domain zf-met PF12874.7 PVD36313.1 - 0.49 10.9 0.0 0.49 10.9 0.0 15.5 15 0 0 15 15 15 0 Zinc-finger of C2H2 type fn3 PF00041.21 PVD36315.1 - 6.7e-40 135.3 6.3 8.3e-11 42.1 0.0 5.3 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.16 PVD36315.1 - 5.5e-31 106.5 0.0 1.1e-11 44.7 0.0 5.2 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36315.1 - 2.9e-29 101.5 0.1 6.4e-10 39.5 0.0 5.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD36315.1 - 1.4e-21 76.6 0.0 2.2e-07 31.1 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD36315.1 - 7.2e-11 42.1 0.0 0.033 14.4 0.0 4.7 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD36315.1 - 1.3e-10 41.4 4.1 0.0081 16.3 0.0 6.1 4 2 0 4 4 4 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 PVD36315.1 - 8e-09 36.0 9.1 0.012 16.2 0.0 5.3 5 0 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD36315.1 - 6.5e-06 26.4 0.2 4 7.8 0.0 3.5 3 0 0 3 3 3 3 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 PVD36315.1 - 6.2e-05 22.5 0.0 7 6.3 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 PVD36315.1 - 0.00032 20.9 0.0 1.3 9.3 0.0 3.9 4 0 0 4 4 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD36315.1 - 0.00036 20.9 0.0 0.2 12.1 0.0 4.0 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD36315.1 - 0.0045 17.0 0.0 1.7 8.7 0.0 3.9 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain MFS_1 PF07690.16 PVD36316.1 - 5.3e-20 71.6 20.7 5.3e-20 71.6 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36316.1 - 0.00031 19.7 4.7 0.00031 19.7 4.7 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter CRF-BP PF05428.11 PVD36318.1 - 2.2e-20 72.7 0.6 2.7e-10 39.5 0.0 2.9 1 1 1 2 2 2 2 Corticotropin-releasing factor binding protein (CRF-BP) Ig_3 PF13927.6 PVD36319.1 - 9.3e-16 58.2 0.3 3.7e-06 27.5 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 PVD36319.1 - 8.3e-13 48.5 0.0 0.00027 21.2 0.0 4.1 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD36319.1 - 5.2e-08 32.8 0.0 0.0013 18.8 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 PVD36319.1 - 5.5e-08 32.9 0.2 0.12 12.6 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD36319.1 - 5.8e-07 29.7 4.4 0.22 11.7 0.2 5.7 4 3 0 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD36319.1 - 0.00088 19.3 0.1 2.5 8.2 0.0 3.9 3 1 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 PVD36320.1 - 7e-18 65.0 0.6 3.1e-06 27.7 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD36320.1 - 5.8e-10 39.1 0.0 0.013 15.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36320.1 - 1.1e-09 38.5 0.2 0.018 15.3 0.0 4.0 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD36320.1 - 3.7e-07 30.2 3.6 0.045 13.9 0.1 4.9 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 PVD36320.1 - 8.3e-06 25.9 1.1 2.5 8.3 0.0 4.6 4 1 0 4 4 4 2 Immunoglobulin V-set domain COX7C PF02935.16 PVD36320.1 - 2.7e-05 24.3 0.1 5.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Chromosome_seg PF13889.6 PVD36321.1 - 1e-19 70.4 1.6 2.5e-19 69.1 1.1 2.0 2 0 0 2 2 2 1 Chromosome segregation during meiosis DUF4210 PF13915.6 PVD36321.1 - 2.5e-16 60.0 0.0 6.6e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Hormone_recep PF00104.30 PVD36322.1 - 9.4e-19 67.8 3.5 1.5e-18 67.2 3.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF3236 PF11576.8 PVD36322.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Hva1_TUDOR PF11160.8 PVD36322.1 - 0.054 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain E_Pc_C PF06752.12 PVD36322.1 - 0.21 11.7 1.4 0.34 11.0 1.4 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus L_HMGIC_fpl PF10242.9 PVD36323.1 - 1.8e-14 54.4 0.0 1.5e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein zf-C3HC4_3 PF13920.6 PVD36324.1 - 1.3e-12 47.4 20.8 1.6e-07 31.1 5.9 4.8 4 1 1 5 5 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36324.1 - 1.6e-12 47.3 23.2 1.5e-07 31.3 7.5 4.2 4 0 0 4 4 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36324.1 - 1.1e-11 44.4 22.9 4.1e-07 29.8 7.0 5.0 4 1 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36324.1 - 1.7e-10 40.9 25.8 1.8e-06 28.0 9.0 4.4 5 1 1 6 6 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36324.1 - 2.1e-10 40.8 24.0 1.7e-06 28.3 8.2 5.1 4 1 0 4 4 3 2 Ring finger domain zf-RING_5 PF14634.6 PVD36324.1 - 2.5e-08 33.7 22.8 1.9e-05 24.5 7.4 4.9 4 1 1 5 5 3 2 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36324.1 - 5.3e-08 32.6 22.1 2.9e-05 23.8 6.8 4.9 4 1 0 4 4 3 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36324.1 - 1.1e-06 28.3 25.9 0.0001 22.1 9.3 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 PVD36324.1 - 7.1e-06 26.0 14.9 0.0021 18.0 2.8 2.4 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain ZNRF_3_ecto PF18212.1 PVD36324.1 - 2e-05 24.5 0.2 0.031 14.3 0.1 2.7 2 0 0 2 2 2 1 ZNRF-3 Ectodomain Lipoprotein_7 PF01540.16 PVD36324.1 - 0.00022 20.6 4.9 0.0021 17.4 0.5 2.5 2 0 0 2 2 2 1 Adhesin lipoprotein HSP70 PF00012.20 PVD36324.1 - 0.00024 19.4 9.1 0.0082 14.4 0.4 2.2 2 0 0 2 2 2 2 Hsp70 protein DUF948 PF06103.11 PVD36324.1 - 0.00044 20.4 8.2 0.21 11.9 0.7 3.6 3 2 0 3 3 2 2 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 PVD36324.1 - 0.0006 19.9 13.9 0.012 15.7 3.1 2.5 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) zf-RING_11 PF17123.5 PVD36324.1 - 0.0011 18.6 19.3 0.11 12.3 6.1 3.1 2 0 0 2 2 2 2 RING-like zinc finger DUF1640 PF07798.11 PVD36324.1 - 0.0092 16.1 2.4 0.0092 16.1 2.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Phasin PF05597.11 PVD36324.1 - 0.011 15.8 11.9 0.14 12.2 2.4 2.6 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CdvA PF18822.1 PVD36324.1 - 0.011 15.6 17.0 0.088 12.6 1.2 3.3 2 2 1 3 3 3 0 CdvA-like coiled-coil domain Spore_Cse60 PF10957.8 PVD36324.1 - 0.015 15.3 4.2 0.043 13.8 1.2 2.6 2 0 0 2 2 2 0 Sporulation protein Cse60 Herpes_UL25 PF01499.16 PVD36324.1 - 0.015 13.8 6.3 0.026 13.0 1.2 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family FapA PF03961.13 PVD36324.1 - 0.021 13.4 8.5 0.023 13.3 0.5 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF892 PF05974.12 PVD36324.1 - 0.033 14.2 11.4 0.13 12.3 2.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF892) MetOD1 PF18546.1 PVD36324.1 - 0.039 13.9 2.3 9.9 6.1 0.0 3.1 2 1 1 3 3 3 0 Metanogen output domain 1 EzrA PF06160.12 PVD36324.1 - 0.11 10.7 12.8 0.19 9.9 4.5 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 PVD36324.1 - 0.14 11.5 9.4 0.55 9.5 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sulfotransfer_3 PF13469.6 PVD36324.1 - 0.2 12.0 1.6 59 3.9 0.0 3.2 3 0 0 3 3 3 0 Sulfotransferase family Baculo_PEP_C PF04513.12 PVD36324.1 - 0.34 10.9 1.9 20 5.2 0.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 PVD36324.1 - 0.36 10.6 16.8 2 8.2 3.9 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 FAM184 PF15665.5 PVD36324.1 - 0.37 10.5 22.2 0.53 10.0 8.1 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B UPF0242 PF06785.11 PVD36324.1 - 0.38 10.8 20.0 2 8.5 8.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YtxH PF12732.7 PVD36324.1 - 0.49 11.0 15.7 3.4 8.3 4.9 2.9 2 0 0 2 2 2 0 YtxH-like protein YpjP PF14005.6 PVD36324.1 - 0.85 9.7 4.0 17 5.4 0.5 2.7 2 0 0 2 2 2 0 YpjP-like protein BORCS6 PF10157.9 PVD36324.1 - 1.1 9.4 5.1 5.9 7.1 0.4 2.6 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF4226 PF10774.9 PVD36324.1 - 1.8 8.9 8.2 13 6.1 0.5 3.6 3 1 1 4 4 3 0 Domain of unknown function (DUF4226) DUF3584 PF12128.8 PVD36324.1 - 1.9 5.9 15.8 0.82 7.1 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 PVD36324.1 - 2 8.2 16.4 8.7 6.1 3.0 3.6 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MCPsignal PF00015.21 PVD36324.1 - 2.2 8.0 11.8 2.9 7.7 0.2 3.6 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.6 PVD36324.1 - 2.8 6.5 11.5 0.45 9.1 2.3 2.2 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 PVD36324.1 - 2.8 6.7 5.3 5.1 5.9 0.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein PIN_8 PF18476.1 PVD36324.1 - 4.4 7.1 13.4 7.3 6.4 3.4 2.8 2 1 0 2 2 2 0 PIN like domain Rx_N PF18052.1 PVD36324.1 - 4.9 7.5 17.0 0.99 9.7 3.9 3.5 2 1 1 3 3 3 0 Rx N-terminal domain DUF5082 PF16888.5 PVD36324.1 - 5.3 7.3 14.0 3.9 7.8 1.2 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) Nnf1 PF03980.14 PVD36324.1 - 9.2 6.7 14.5 0.24 11.8 3.9 2.6 2 1 0 2 2 2 0 Nnf1 Allexi_40kDa PF05549.11 PVD36324.1 - 9.3 5.7 9.3 6.5 6.2 0.4 2.6 3 0 0 3 3 3 0 Allexivirus 40kDa protein zf-B_box PF00643.24 PVD36325.1 - 2.5e-10 40.4 8.6 2.5e-10 40.4 8.6 4.3 5 1 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD36325.1 - 8.6e-09 35.3 10.0 8.6e-09 35.3 10.0 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36325.1 - 1e-08 34.9 9.0 1e-08 34.9 9.0 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36325.1 - 1.5e-08 34.6 10.8 1.5e-08 34.6 10.8 3.6 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD36325.1 - 1.6e-08 34.3 8.0 1.6e-08 34.3 8.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36325.1 - 3e-08 33.9 10.3 3e-08 33.9 10.3 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36325.1 - 7.8e-07 28.8 9.3 7.8e-07 28.8 9.3 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36325.1 - 2.2e-06 27.5 8.0 2.2e-06 27.5 8.0 4.0 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36325.1 - 0.00013 21.8 9.4 0.00013 21.8 9.4 4.2 3 2 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD36325.1 - 1.3 8.8 10.3 0.25 11.1 5.8 2.3 2 0 0 2 2 2 0 RING-like zinc finger CoiA PF06054.11 PVD36325.1 - 2.2 7.3 5.5 4 6.5 1.2 2.1 2 0 0 2 2 2 0 Competence protein CoiA-like family LRR_8 PF13855.6 PVD36326.1 - 4.2e-23 80.9 11.8 1.3e-11 44.1 1.6 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PVD36326.1 - 1.1e-14 54.3 18.9 2.2e-05 24.7 0.1 5.4 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD36326.1 - 4.6e-05 23.4 5.0 0.002 18.1 1.7 2.2 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PVD36326.1 - 0.00062 19.6 2.5 13 6.2 0.5 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 PVD36326.1 - 0.0018 17.8 3.9 0.96 8.9 1.4 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PVD36326.1 - 0.0024 18.2 10.1 0.23 12.1 0.6 5.7 6 1 0 6 6 6 1 Leucine Rich Repeat DUF530 PF04409.12 PVD36326.1 - 0.18 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) LRR_8 PF13855.6 PVD36327.1 - 2.3e-23 81.7 7.7 2.5e-14 52.8 0.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat TIR PF01582.20 PVD36327.1 - 6.1e-21 75.0 0.0 9.7e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD36327.1 - 1.6e-18 67.4 0.0 3.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD36327.1 - 1.3e-10 41.4 10.2 3.3e-06 27.3 0.3 4.0 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD36327.1 - 3.7e-09 36.6 3.5 8.7e-09 35.4 1.5 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD36327.1 - 0.0013 19.0 8.7 36 5.5 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat DUF1863 PF08937.11 PVD36327.1 - 0.0046 17.3 0.0 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) YjcZ PF13990.6 PVD36327.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein LRR_6 PF13516.6 PVD36327.1 - 0.42 10.8 13.3 9.5 6.6 0.1 5.6 6 1 1 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 PVD36328.1 - 2e-41 139.5 25.0 1.1e-14 54.0 0.8 6.5 3 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PVD36328.1 - 4.4e-24 84.2 40.8 4.6e-06 26.9 1.2 9.2 4 3 5 10 10 10 5 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD36328.1 - 2.9e-20 72.8 0.1 7e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 PVD36328.1 - 1.4e-18 67.6 0.0 7.7e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 TIR domain LRR_5 PF13306.6 PVD36328.1 - 8.7e-14 51.6 18.1 9.2e-09 35.3 2.3 4.2 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD36328.1 - 5.9e-05 22.6 7.6 6.1 6.3 0.8 5.0 2 1 1 5 5 5 2 Leucine-rich repeat DUF1863 PF08937.11 PVD36328.1 - 0.013 15.8 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 PVD36328.1 - 0.046 14.3 24.9 1.4 9.8 0.6 8.9 11 1 0 11 11 11 0 Leucine Rich Repeat DUF530 PF04409.12 PVD36328.1 - 0.2 10.0 0.1 0.3 9.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DUF4866 PF16160.5 PVD36328.1 - 0.74 9.1 3.7 2.7 7.3 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4866) Filamin PF00630.19 PVD36329.1 - 1.4e-07 32.3 0.1 1.5e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat Filamin PF00630.19 PVD36331.1 - 0.06 14.2 0.0 0.065 14.1 0.0 1.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat NAD_binding_6 PF08030.12 PVD36334.1 - 1.8e-26 93.1 0.0 2.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PVD36334.1 - 1.6e-20 73.2 0.0 4.9e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 PVD36334.1 - 4.6e-20 72.0 11.2 4.6e-20 72.0 11.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 PVD36334.1 - 2.1e-17 61.3 6.6 1.6e-05 24.1 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PVD36334.1 - 2.7e-17 61.1 6.8 2.5e-05 23.8 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PVD36334.1 - 4.6e-12 46.2 5.5 8.2e-08 32.6 0.7 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PVD36334.1 - 1.9e-11 42.9 8.8 0.00052 19.4 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PVD36334.1 - 1.3e-05 24.9 5.4 0.098 12.5 0.4 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 PVD36334.1 - 3.1e-05 24.2 0.0 2.4 8.6 0.0 3.4 1 1 2 3 3 3 2 EF-hand domain FAD_binding_6 PF00970.24 PVD36334.1 - 0.0054 17.1 0.0 0.041 14.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PVD36334.1 - 0.0062 17.2 0.0 0.037 14.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PfkB PF00294.24 PVD36335.1 - 1.6e-33 116.3 0.0 1.9e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-RING_14 PF17978.1 PVD36335.1 - 0.078 13.4 0.4 5.5 7.5 0.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ANF_receptor PF01094.28 PVD36335.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Abhydrolase_1 PF00561.20 PVD36336.1 - 4.3e-11 42.9 0.1 5e-09 36.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD36336.1 - 1.2e-06 27.9 0.0 7.6e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PVD36336.1 - 0.0028 17.5 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 PVD36336.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Fasciclin PF02469.22 PVD36337.1 - 3.7e-84 279.3 0.1 3.9e-21 75.6 0.0 7.5 7 1 0 7 7 7 7 Fasciclin domain BDHCT PF08072.11 PVD36337.1 - 0.00086 19.3 0.2 0.49 10.5 0.0 2.6 2 0 0 2 2 2 2 BDHCT (NUC031) domain ChuX_HutX PF06228.13 PVD36337.1 - 0.018 14.8 0.0 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX AroM PF07302.11 PVD36337.1 - 0.041 13.3 0.0 8.2 5.7 0.0 2.5 2 0 0 2 2 2 0 AroM protein CUB_2 PF02408.20 PVD36337.1 - 0.061 13.1 1.3 5.1 6.9 0.1 3.1 2 0 0 2 2 2 0 CUB-like domain FAST_1 PF06743.15 PVD36337.1 - 0.47 10.4 2.9 40 4.3 0.1 3.2 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Fasciclin PF02469.22 PVD36338.1 - 2.3e-47 160.4 0.2 9.9e-21 74.3 0.0 4.2 4 0 0 4 4 4 3 Fasciclin domain BDHCT PF08072.11 PVD36338.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 BDHCT (NUC031) domain VPS13_mid_rpt PF16910.5 PVD36339.1 - 1.2e-77 260.6 11.1 2.5e-64 217.0 0.1 6.3 5 1 0 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 PVD36339.1 - 1.8e-70 237.4 9.6 5e-69 232.7 2.8 4.0 4 1 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PVD36339.1 - 4e-25 88.2 0.5 2.8e-24 85.4 0.5 2.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATR13 PF16829.5 PVD36339.1 - 0.13 12.6 0.0 19 5.6 0.0 3.5 3 0 0 3 3 3 0 Avirulence protein ATR13, RxLR effector VPS13_C PF16909.5 PVD36340.1 - 1.5e-65 220.4 3.2 1.3e-61 207.4 0.1 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 PVD36340.1 - 1.5e-32 113.1 0.3 9.4e-31 107.2 0.1 2.3 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 PVD36340.1 - 6.6e-09 36.0 0.0 4.2e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 PVD36340.1 - 0.00077 18.4 0.1 0.0029 16.6 0.3 1.7 2 0 0 2 2 2 1 Golgi-body localisation protein domain WWE PF02825.20 PVD36340.1 - 0.004 17.7 0.5 0.034 14.7 0.0 2.6 2 0 0 2 2 2 1 WWE domain RabGAP-TBC PF00566.18 PVD36341.1 - 6.8e-30 104.3 7.3 1.7e-29 103.0 1.4 2.4 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Myb_DNA-bind_5 PF13873.6 PVD36342.1 - 8.8e-13 48.1 2.4 2.5e-12 46.7 2.4 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PVD36342.1 - 3.3e-08 33.8 1.8 3.3e-08 33.8 1.8 2.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 PVD36342.1 - 0.0082 16.4 0.5 0.0082 16.4 0.5 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 PVD36342.1 - 0.071 13.3 1.1 0.18 12.0 1.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain RRS1 PF04939.12 PVD36342.1 - 0.55 10.1 8.9 0.17 11.8 0.6 2.4 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Methyltransf_22 PF13383.6 PVD36343.1 - 7e-11 42.2 0.1 9.1e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PVD36343.1 - 5.9e-05 23.2 0.2 0.00016 21.8 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain WD40 PF00400.32 PVD36343.1 - 0.11 13.4 0.3 0.33 11.9 0.3 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat NHL PF01436.21 PVD36344.1 - 2e-21 74.8 13.5 1.6e-05 24.7 0.0 6.0 6 0 0 6 6 6 5 NHL repeat DUF5128 PF17170.4 PVD36344.1 - 7.8e-07 28.5 3.4 0.99 8.5 0.1 4.7 2 2 3 5 5 5 5 6-bladed beta-propeller SGL PF08450.12 PVD36344.1 - 0.00028 20.6 0.0 0.39 10.3 0.0 3.3 2 2 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SdiA-regulated PF06977.11 PVD36344.1 - 0.22 10.7 0.0 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 SdiA-regulated Pyridoxal_deC PF00282.19 PVD36345.1 - 1.4e-155 517.7 0.0 3.3e-155 516.4 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain zf-C2HC_2 PF13913.6 PVD36345.1 - 0.0007 19.4 1.6 1.2 9.1 0.7 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type Beta_elim_lyase PF01212.21 PVD36345.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MTHFR PF02219.17 PVD36346.1 - 1.2e-101 339.9 0.0 1.6e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Radical_SAM PF04055.21 PVD36346.1 - 0.0076 16.7 0.0 6 7.2 0.0 2.6 1 1 2 3 3 3 2 Radical SAM superfamily Mesd PF10185.9 PVD36347.1 - 1.3e-49 168.1 5.8 2.3e-31 108.8 2.0 2.2 1 1 1 2 2 2 2 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.6 PVD36347.1 - 0.022 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Conotoxin PF02950.17 PVD36347.1 - 0.28 12.2 2.3 0.52 11.4 0.0 2.3 2 0 0 2 2 2 0 Conotoxin RlaP PF10127.9 PVD36348.1 - 6e-14 52.2 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 PVD36348.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Galactosyl_T PF01762.21 PVD36350.1 - 6.1e-38 130.6 0.0 1.1e-37 129.8 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Peptidase_S49_N PF08496.10 PVD36350.1 - 0.4 10.7 3.8 0.76 9.8 3.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.22 PVD36350.1 - 1.6 7.9 5.0 2.5 7.2 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PVD36350.1 - 4.2 6.0 7.2 7.6 5.2 7.2 1.4 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 PVD36351.1 - 1.8e-23 82.3 13.6 5e-05 24.0 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 PVD36351.1 - 5e-06 25.5 0.2 0.088 11.5 0.0 3.6 3 0 0 3 3 3 3 Nup133 N terminal like EF-hand_7 PF13499.6 PVD36351.1 - 0.013 15.9 0.5 0.056 13.9 0.5 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 PVD36351.1 - 0.033 14.1 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair ANAPC4_WD40 PF12894.7 PVD36351.1 - 0.037 14.3 0.3 1.4 9.2 0.1 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain I_LWEQ PF01608.17 PVD36353.1 - 7.1e-72 240.7 199.3 3.8e-49 166.9 13.4 17.9 7 4 11 19 19 19 9 I/LWEQ domain Talin_middle PF09141.10 PVD36353.1 - 4e-55 186.3 2.7 4e-55 186.3 2.7 15.6 9 4 2 13 13 12 5 Talin, middle domain VBS PF08913.10 PVD36353.1 - 1.7e-47 161.0 8.1 4e-45 153.3 1.9 12.6 11 3 2 14 14 14 4 Vinculin Binding Site FERM_f0 PF16511.5 PVD36353.1 - 2.7e-38 130.1 0.0 6e-36 122.6 0.0 3.1 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 PVD36353.1 - 6.4e-20 71.7 0.0 6.4e-20 71.7 0.0 4.1 3 1 0 3 3 2 1 FERM central domain FERM_N PF09379.10 PVD36353.1 - 3.1e-19 68.7 0.4 2.1e-16 59.6 1.1 3.2 2 1 0 2 2 2 1 FERM N-terminal domain IRS PF02174.17 PVD36353.1 - 1.9e-05 24.5 0.0 5.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 PTB domain (IRS-1 type) TetR_C_30 PF17939.1 PVD36353.1 - 0.033 14.4 1.2 0.17 12.2 0.3 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Noelin-1 PF12308.8 PVD36353.1 - 0.046 13.7 0.0 11 6.1 0.0 5.0 4 0 0 4 4 4 0 Neurogenesis glycoprotein FliS_cochap PF16522.5 PVD36353.1 - 1.8 8.5 7.4 0.72 9.8 0.1 3.9 3 0 0 3 3 3 0 Flagellar FLiS export co-chaperone, HP1076 Peptidase_M3_N PF08439.10 PVD36353.1 - 4.8 7.5 5.9 34 4.8 1.9 3.9 2 0 0 2 2 2 0 Oligopeptidase F adh_short PF00106.25 PVD36354.1 - 1.3e-24 86.8 0.1 2e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD36354.1 - 3.7e-23 82.3 0.2 5.9e-23 81.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 PVD36354.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Ub-RnfH PF03658.14 PVD36354.1 - 0.0056 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 RnfH family Ubiquitin Lar_N PF09861.9 PVD36354.1 - 0.0086 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Lactate racemase N-terminal domain KR PF08659.10 PVD36354.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 PVD36354.1 - 0.024 14.5 0.2 0.082 12.8 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 PVD36355.1 - 5.3e-24 84.8 0.2 8.4e-24 84.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD36355.1 - 2.1e-22 79.8 0.3 3.2e-22 79.2 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 PVD36355.1 - 0.0072 16.2 0.1 0.048 13.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 PVD36355.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD36355.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Lar_N PF09861.9 PVD36355.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain SARAF PF06682.12 PVD36356.1 - 2.2e-05 24.3 0.5 4.2e-05 23.4 0.6 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis LapA_dom PF06305.11 PVD36356.1 - 0.00083 19.1 0.2 0.0014 18.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Zip PF02535.22 PVD36356.1 - 0.0032 16.8 0.8 0.0038 16.5 0.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter TMEM51 PF15345.6 PVD36356.1 - 0.017 14.9 0.4 0.023 14.6 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 RIC3 PF15361.6 PVD36356.1 - 0.018 15.4 1.2 0.018 15.4 1.2 1.6 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 TssO PF17561.2 PVD36356.1 - 0.039 14.1 0.6 0.062 13.4 0.6 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO SCIMP PF15050.6 PVD36356.1 - 0.045 14.2 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein Conotoxin PF02950.17 PVD36356.1 - 0.071 14.1 0.5 0.071 14.1 0.5 1.8 2 0 0 2 2 1 0 Conotoxin PAP_PilO PF06864.12 PVD36356.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) UPF0542 PF15086.6 PVD36356.1 - 0.18 11.8 1.6 0.34 10.9 1.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 NicO PF03824.16 PVD36356.1 - 0.28 10.5 0.6 0.33 10.3 0.6 1.3 1 1 0 1 1 1 0 High-affinity nickel-transport protein Ctr PF04145.15 PVD36356.1 - 0.43 11.2 1.2 0.66 10.6 1.2 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF4834 PF16118.5 PVD36356.1 - 0.57 11.2 4.4 2.5 9.1 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Sec62 PF03839.16 PVD36356.1 - 2 7.8 4.8 2.9 7.4 4.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 PVD36356.1 - 4.1 7.1 5.0 1.2 8.9 2.0 1.6 1 1 1 2 2 2 0 Connexin RuvC_III PF18541.1 PVD36356.1 - 5.2 7.0 9.5 4.2 7.3 2.8 2.1 1 1 1 2 2 2 0 RuvC endonuclease subdomain 3 Glyco_hydro_38N PF01074.22 PVD36357.1 - 3.7e-102 341.6 1.5 5.4e-102 341.1 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PVD36357.1 - 4.1e-28 98.9 0.0 1e-27 97.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PVD36357.1 - 7.1e-23 80.6 0.1 1.9e-22 79.2 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain SAM_DrpA PF18255.1 PVD36357.1 - 0.11 12.8 0.2 5.2 7.4 0.1 3.0 3 0 0 3 3 3 0 DNA processing protein A sterile alpha motif domain Glyco_hydro_20 PF00728.22 PVD36358.1 - 8.5e-180 597.7 0.0 1.8e-90 303.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 PVD36358.1 - 8.6e-54 181.5 0.0 4.5e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 PVD36358.1 - 1.4e-44 150.0 0.3 7.4e-21 73.9 0.0 3.3 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 PVD36358.1 - 9.1e-31 107.2 0.2 2.6e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 7tm_1 PF00001.21 PVD36358.1 - 2e-16 60.2 13.5 2.7e-16 59.7 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glycohydro_20b2 PF14845.6 PVD36358.1 - 2.4e-05 25.0 0.0 0.14 12.8 0.0 2.6 2 0 0 2 2 2 2 beta-acetyl hexosaminidase like 7TM_GPCR_Srx PF10328.9 PVD36358.1 - 0.00022 20.9 9.2 0.00042 20.0 9.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Glyco_hydro_67N PF03648.14 PVD36358.1 - 0.0015 18.8 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus 7TM_GPCR_Srw PF10324.9 PVD36358.1 - 0.0051 16.1 8.5 0.018 14.3 8.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 PVD36358.1 - 0.4 10.3 13.6 0.81 9.3 13.6 1.4 1 1 0 1 1 1 0 Srg family chemoreceptor Sushi PF00084.20 PVD36359.1 - 1.8e-08 34.9 1.1 2.4e-08 34.4 1.1 1.2 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) ResB PF05140.14 PVD36361.1 - 0.13 11.0 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 ResB-like family Shisa PF13908.6 PVD36361.1 - 0.18 12.0 1.6 14 5.9 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-H2C2_2 PF13465.6 PVD36363.1 - 4.9e-41 137.4 29.5 1.6e-07 31.5 0.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36363.1 - 7.2e-29 98.6 36.2 2.3e-05 24.6 1.8 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36363.1 - 4.6e-22 76.8 41.2 0.00073 20.2 0.2 6.5 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD36363.1 - 2.8e-14 52.6 22.6 0.001 18.8 0.9 5.5 5 0 0 5 5 5 5 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PVD36363.1 - 2.5e-12 46.8 21.3 0.029 14.7 0.1 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD36363.1 - 1.4e-08 34.8 27.4 0.12 12.8 0.9 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf_UBZ PF18439.1 PVD36363.1 - 4.1e-07 29.5 16.6 0.25 11.0 0.1 6.1 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 PVD36363.1 - 2.3e-06 28.2 12.7 0.16 12.7 0.5 3.3 2 1 0 3 3 3 3 zinc-ribbon family ADK_lid PF05191.14 PVD36363.1 - 3.3e-06 27.0 6.4 1.6 8.7 0.0 4.9 2 2 1 3 3 3 2 Adenylate kinase, active site lid Rpr2 PF04032.16 PVD36363.1 - 3.3e-05 24.1 15.3 0.0012 19.1 0.6 4.5 1 1 2 4 4 4 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HE PF16278.5 PVD36363.1 - 3.4e-05 24.2 22.4 0.049 14.1 0.8 5.2 2 2 3 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 PVD36363.1 - 0.00012 22.0 5.5 0.0011 19.0 0.5 7.0 6 2 0 6 6 6 3 C2H2-type zinc finger DUF3268 PF11672.8 PVD36363.1 - 0.00025 21.3 10.9 0.066 13.5 0.1 3.9 2 1 2 4 4 4 2 zinc-finger-containing domain zf-trcl PF13451.6 PVD36363.1 - 0.00033 20.5 17.0 2 8.4 0.1 6.1 6 0 0 6 6 6 1 Probable zinc-ribbon domain XPA_N PF01286.18 PVD36363.1 - 0.0006 19.8 22.5 2.8 8.1 0.2 6.0 6 0 0 6 6 6 2 XPA protein N-terminal GAGA PF09237.11 PVD36363.1 - 0.00068 19.4 8.4 3.4 7.6 0.3 4.4 3 1 0 4 4 4 2 GAGA factor Zn-ribbon_8 PF09723.10 PVD36363.1 - 0.0029 17.7 27.5 0.1 12.7 1.9 5.5 2 1 4 6 6 6 3 Zinc ribbon domain zf-AN1 PF01428.16 PVD36363.1 - 0.025 14.7 28.5 6.7 7.0 0.2 6.2 4 2 2 6 6 6 0 AN1-like Zinc finger HalOD2 PF18547.1 PVD36363.1 - 0.036 14.0 8.8 0.069 13.1 0.1 3.7 3 1 0 3 3 3 0 Halobacterial output domain 2 DZR PF12773.7 PVD36363.1 - 0.061 13.3 22.7 1.8e+04 -5.6 22.7 3.9 1 1 0 1 1 0 0 Double zinc ribbon zf-H2C2_5 PF13909.6 PVD36363.1 - 0.071 12.9 48.5 0.09 12.5 6.4 7.4 7 3 0 7 7 6 0 C2H2-type zinc-finger domain DUF1163 PF06651.11 PVD36363.1 - 0.076 13.1 3.9 3.9 7.6 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1163) zf_C2H2_ZHX PF18387.1 PVD36363.1 - 0.1 12.2 22.0 3 7.5 0.2 5.3 1 1 4 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain MaoC_dehydratas PF01575.19 PVD36363.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain PHD PF00628.29 PVD36363.1 - 0.12 12.3 21.9 1.5 8.8 9.7 4.5 3 2 2 5 5 5 0 PHD-finger Rubredoxin_2 PF18073.1 PVD36363.1 - 0.31 10.8 26.4 1.5 8.6 0.5 5.9 6 0 0 6 6 6 0 Rubredoxin metal binding domain zf-BED PF02892.15 PVD36363.1 - 0.59 10.2 25.2 1.4 9.0 3.5 5.1 3 2 1 4 4 3 0 BED zinc finger zf-U1 PF06220.12 PVD36363.1 - 0.84 9.5 0.1 0.84 9.5 0.1 4.1 3 1 1 4 4 4 0 U1 zinc finger Elf1 PF05129.13 PVD36363.1 - 0.85 9.7 20.3 1.3 9.1 1.3 4.3 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.6 PVD36363.1 - 1.7 9.2 19.0 4 8.0 0.3 4.5 2 2 1 3 3 2 0 Recombinase zinc beta ribbon domain HypA PF01155.19 PVD36363.1 - 2.3 8.3 15.4 5.3 7.1 0.7 3.5 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATPase-cat_bd PF12156.8 PVD36363.1 - 7.6 7.3 16.9 0.92 10.3 2.0 3.3 2 1 2 4 4 4 0 Putative metal-binding domain of cation transport ATPase zf-Sec23_Sec24 PF04810.15 PVD36363.1 - 7.8 6.6 14.3 6.5 6.9 0.1 5.1 5 1 0 5 5 5 0 Sec23/Sec24 zinc finger DNA_RNApol_7kD PF03604.13 PVD36363.1 - 9.6 6.0 17.5 20 4.9 0.2 5.6 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit PMP22_Claudin PF00822.20 PVD36364.1 - 4.8e-11 42.8 9.5 4.8e-08 33.1 4.3 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 PVD36364.1 - 3.9e-05 23.5 0.9 3.9e-05 23.5 0.9 2.9 2 1 0 3 3 3 1 Amastin surface glycoprotein L_HMGIC_fpl PF10242.9 PVD36364.1 - 5.8e-05 23.4 7.9 0.03 14.5 4.3 3.0 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein DASH_Dam1 PF08653.10 PVD36364.1 - 0.00016 21.4 0.1 0.042 13.7 0.0 2.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 Claudin_3 PF06653.11 PVD36364.1 - 0.034 14.1 12.5 3.1 7.7 1.1 3.8 3 2 0 3 3 3 0 Tight junction protein, Claudin-like DUF3149 PF11346.8 PVD36364.1 - 0.096 12.3 1.0 9.7 5.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) CybS PF05328.12 PVD36364.1 - 0.23 11.1 1.6 0.72 9.5 0.2 2.2 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit Bax1-I PF01027.20 PVD36364.1 - 0.59 9.9 16.4 0.047 13.5 7.7 2.3 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 SAYSvFN PF10260.9 PVD36364.1 - 1.3 9.0 4.8 9.4 6.2 0.1 3.0 4 0 0 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) TAS2R PF05296.13 PVD36365.1 - 0.004 16.3 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) Clc-like PF07062.12 PVD36365.1 - 0.013 15.0 0.2 0.013 15.0 0.2 3.4 2 2 1 3 3 3 0 Clc-like PepSY_TM PF03929.16 PVD36365.1 - 0.086 12.5 4.1 3.9 7.0 0.0 2.9 3 1 0 3 3 3 0 PepSY-associated TM region YjcB PF15940.5 PVD36365.1 - 0.093 12.9 0.5 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function DUF4286 PF14114.6 PVD36365.1 - 0.12 12.9 0.2 17 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) PMP22_Claudin PF00822.20 PVD36365.1 - 0.12 12.3 19.6 1.7 8.5 9.1 4.2 4 1 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family DUF4179 PF13786.6 PVD36365.1 - 0.2 12.2 2.4 30 5.2 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4179) DUF2076 PF09849.9 PVD36365.1 - 0.22 11.6 4.6 7 6.6 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PMP22_Claudin PF00822.20 PVD36366.1 - 0.00058 19.8 7.9 0.00085 19.2 7.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1634 PF07843.11 PVD36366.1 - 0.007 16.4 2.7 1 9.4 0.5 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1634) Clc-like PF07062.12 PVD36366.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.1 1 1 1 2 2 2 0 Clc-like Claudin_3 PF06653.11 PVD36366.1 - 0.096 12.6 8.8 0.27 11.2 8.8 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4293 PF14126.6 PVD36366.1 - 0.6 10.4 2.2 0.96 9.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) TRIQK PF15168.6 PVD36366.1 - 0.99 9.3 2.5 6.2 6.8 0.2 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family SelP_N PF04592.14 PVD36366.1 - 1.1 8.6 7.5 1.7 8.0 7.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Claudin_2 PF13903.6 PVD36366.1 - 1.1 8.9 13.4 0.31 10.8 9.7 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspanin PF00335.20 PVD36366.1 - 1.2 8.8 5.3 0.13 12.0 1.0 1.5 2 0 0 2 2 2 0 Tetraspanin family Wzy_C PF04932.15 PVD36366.1 - 1.3 8.7 6.7 1.6e+02 1.9 6.7 3.0 1 1 0 1 1 1 0 O-Antigen ligase Pox_A14 PF05767.12 PVD36366.1 - 3.3 7.9 8.0 0.26 11.5 1.4 2.3 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Ank_2 PF12796.7 PVD36367.1 - 1.5e-37 128.1 2.1 2.1e-08 34.6 0.0 6.3 4 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD36367.1 - 1.5e-30 105.2 11.0 0.0013 19.3 0.0 10.3 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD36367.1 - 3.9e-29 99.8 9.5 0.001 19.4 0.0 10.5 11 0 0 11 11 11 5 Ankyrin repeat Ank_3 PF13606.6 PVD36367.1 - 3.3e-27 91.5 11.0 0.0013 19.1 0.0 10.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PVD36367.1 - 1.3e-21 76.3 7.6 0.0015 18.8 0.0 8.3 7 2 2 9 9 9 6 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 PVD36368.1 - 2.7e-14 52.7 4.1 4.1e-11 42.5 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD36368.1 - 1.2e-13 49.6 6.7 3.3e-08 32.5 1.2 2.6 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD36368.1 - 1.6e-13 50.8 4.5 7.2e-10 39.2 1.6 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD36368.1 - 9.1e-09 34.6 5.0 6.2e-05 22.6 0.4 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD36368.1 - 3.8e-05 23.0 5.2 0.00024 20.5 1.5 2.5 2 0 0 2 2 2 1 EF hand SUB1_ProdP9 PF18213.1 PVD36368.1 - 0.022 14.6 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 HipA_C PF07804.12 PVD36368.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 HipA-like C-terminal domain EGF PF00008.27 PVD36370.1 - 0.0098 16.2 14.1 0.03 14.6 9.9 2.3 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 PVD36370.1 - 0.85 10.1 14.2 0.26 11.7 9.8 2.1 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 PVD36370.1 - 3.4 8.4 18.1 0.57 10.9 12.8 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Y_Y_Y PF07495.13 PVD36371.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Pkinase_Tyr PF07714.17 PVD36372.1 - 6.9e-65 218.9 0.2 3.1e-64 216.7 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36372.1 - 2.3e-26 92.7 0.0 8.8e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain fn3 PF00041.21 PVD36372.1 - 2.5e-08 34.1 0.1 7.7e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Amnionless PF14828.6 PVD36372.1 - 0.00096 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Amnionless DUF2207 PF09972.9 PVD36372.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kinase-like PF14531.6 PVD36372.1 - 0.049 12.9 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MtrF PF09472.10 PVD36372.1 - 0.16 11.4 3.6 0.41 10.1 3.6 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3377 PF11857.8 PVD36372.1 - 0.18 11.7 0.8 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Syndecan PF01034.20 PVD36372.1 - 0.42 10.5 5.0 1.2 9.1 5.0 1.7 1 0 0 1 1 1 0 Syndecan domain ANAPC16 PF17256.2 PVD36373.1 - 0.044 14.2 0.2 0.09 13.2 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 16 Sec62 PF03839.16 PVD36373.1 - 8.9 5.8 8.5 11 5.5 8.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Mito_carr PF00153.27 PVD36374.1 - 8.2e-30 102.6 0.3 9e-12 44.8 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF641 PF04859.12 PVD36375.1 - 0.011 16.0 1.6 0.011 16.0 1.6 4.2 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) RFX_DNA_binding PF02257.15 PVD36376.1 - 4.8e-22 78.4 0.0 9.9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain RFX5_N PF18326.1 PVD36376.1 - 5e-07 29.4 0.1 2.2e-06 27.3 0.1 2.1 1 0 0 1 1 1 1 RFX5 N-terminal domain Pox_D5 PF03288.16 PVD36376.1 - 0.02 15.4 0.3 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like Vfa1 PF08432.10 PVD36380.1 - 0.057 13.7 0.3 0.94 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 LPMO_10 PF03067.15 PVD36381.1 - 2.3e-34 119.7 0.4 3.6e-34 119.1 0.4 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 PVD36382.1 - 4.2e-35 122.2 2.5 5.2e-35 121.9 2.5 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading fn3 PF00041.21 PVD36383.1 - 4.2e-08 33.4 0.6 7.7e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD36383.1 - 0.0054 17.3 0.4 0.039 14.5 0.1 2.3 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD36383.1 - 0.038 14.3 0.1 0.093 13.1 0.1 1.7 1 1 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Ig_3 PF13927.6 PVD36384.1 - 3.9e-07 30.6 0.1 1.1e-06 29.1 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD36384.1 - 2.9e-06 27.2 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36384.1 - 7.4e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD36384.1 - 0.00011 22.2 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD36384.1 - 0.032 14.3 0.1 0.094 12.8 0.0 1.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 PVD36384.1 - 0.039 14.3 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain fn3 PF00041.21 PVD36385.1 - 3.9e-47 158.5 6.4 2.3e-10 40.7 0.0 6.4 5 1 1 6 6 6 6 Fibronectin type III domain I-set PF07679.16 PVD36385.1 - 1.2e-10 41.2 0.1 8.4e-10 38.6 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36385.1 - 3.2e-09 37.3 0.0 1.6e-08 35.0 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD36385.1 - 2.1e-08 34.6 3.3 0.16 12.5 0.1 5.4 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain ig PF00047.25 PVD36385.1 - 1.4e-06 28.4 0.1 6.2e-06 26.3 0.1 2.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD36385.1 - 2e-06 28.0 0.0 6.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Interfer-bind PF09294.10 PVD36385.1 - 6.3e-05 23.2 0.1 4.1 7.8 0.0 4.3 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 PVD36385.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Kinesin PF00225.23 PVD36386.1 - 1.1e-53 182.4 0.2 1.6e-53 181.8 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 PVD36386.1 - 3.6e-26 91.3 0.2 7.8e-26 90.2 0.2 1.5 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Crystall_4 PF17945.1 PVD36386.1 - 0.029 14.8 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Phosphatase PF15698.5 PVD36386.1 - 0.05 12.7 0.0 0.55 9.3 0.0 2.0 2 0 0 2 2 2 0 Phosphatase Kinesin PF00225.23 PVD36387.1 - 6.4e-75 252.1 5.8 5.5e-72 242.5 0.2 2.6 2 1 1 3 3 3 2 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 PVD36387.1 - 2e-36 124.3 0.1 5.8e-36 122.8 0.1 1.8 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 PVD36387.1 - 2.1e-05 24.5 6.8 0.0016 18.4 0.1 3.5 3 0 0 3 3 3 2 Microtubule binding Sua5_yciO_yrdC PF01300.18 PVD36387.1 - 0.01 15.3 0.1 0.028 13.9 0.1 1.8 1 0 0 1 1 1 0 Telomere recombination Crystall_4 PF17945.1 PVD36387.1 - 0.07 13.6 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF3786 PF12654.7 PVD36387.1 - 0.073 12.7 0.1 5.8 6.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3786) DltD PF04914.12 PVD36387.1 - 6.4 6.1 12.3 11 5.3 12.3 1.3 1 0 0 1 1 1 0 DltD protein Peptidase_S24 PF00717.23 PVD36388.1 - 2.9e-10 40.0 0.1 4.5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_C1 PF00112.23 PVD36389.1 - 1.4e-42 146.2 0.0 2.3e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease YadA_head PF05658.14 PVD36389.1 - 0.062 13.7 0.2 0.14 12.6 0.2 1.6 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin Peptidase_C1 PF00112.23 PVD36390.1 - 1.4e-80 270.4 3.6 1.8e-80 270.1 3.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD36390.1 - 1.2e-11 44.9 2.1 1.9e-11 44.2 2.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD36390.1 - 0.00016 20.6 4.5 0.014 14.2 0.7 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 PVD36391.1 - 7.6e-88 294.2 6.7 9.4e-88 293.9 6.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD36391.1 - 6.5e-08 32.9 0.1 1.3e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD36391.1 - 8.9e-05 21.4 4.3 0.022 13.6 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 PVD36392.1 - 1.4e-40 139.8 2.2 2e-40 139.2 2.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD36392.1 - 5e-08 33.3 0.5 8.9e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 PVD36393.1 - 8e-82 274.5 4.4 1e-81 274.2 4.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD36393.1 - 6e-13 49.0 2.8 1e-12 48.2 2.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD36393.1 - 0.00076 18.4 3.0 0.14 10.9 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 PVD36394.1 - 4.4e-48 164.2 0.3 6.2e-48 163.8 0.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease zf-ACC PF17848.1 PVD36395.1 - 0.021 14.9 0.9 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Peptidase_C1 PF00112.23 PVD36396.1 - 1.9e-85 286.4 5.9 2.7e-85 285.9 5.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD36396.1 - 1.2e-11 44.9 3.3 1.9e-11 44.2 3.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD36396.1 - 0.00023 20.1 3.5 0.022 13.6 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Lsm_interact PF05391.11 PVD36396.1 - 0.073 12.6 0.4 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 Lsm interaction motif TDP43_N PF18694.1 PVD36397.1 - 7.4e-30 102.6 0.0 1.2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 PVD36397.1 - 3.5e-25 87.6 0.0 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD36397.1 - 1.2e-06 28.5 0.2 0.05 13.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RL PF17797.1 PVD36397.1 - 6.1e-06 26.1 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 1 RL domain Nup35_RRM_2 PF14605.6 PVD36397.1 - 0.072 13.1 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PVD36397.1 - 0.073 13.1 0.0 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif LRR_6 PF13516.6 PVD36398.1 - 1.7e-08 33.8 23.4 4 7.7 0.0 10.8 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 PVD36398.1 - 0.0024 18.2 18.1 12 6.4 0.0 8.7 6 4 6 12 12 12 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD36398.1 - 6.8 7.7 28.7 41 5.3 0.1 9.7 11 0 0 11 11 11 0 Leucine Rich Repeat G-alpha PF00503.20 PVD36399.1 - 5.2e-118 394.3 3.8 6.4e-118 394.0 3.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD36399.1 - 7.5e-14 51.6 2.0 1.7e-10 40.7 0.3 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD36399.1 - 0.0018 17.7 2.9 0.057 12.8 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD36399.1 - 0.037 14.2 0.3 3.6 7.8 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 PVD36400.1 - 1.2e-69 234.4 0.0 1.9e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36400.1 - 4e-30 105.1 0.1 1.9e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain fn3 PF00041.21 PVD36400.1 - 3.3e-09 37.0 2.6 2.9e-07 30.7 0.3 3.6 3 0 0 3 3 3 1 Fibronectin type III domain Kinase-like PF14531.6 PVD36400.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_60s PF00428.19 PVD36401.1 - 4.4 8.0 0.0 4.4 8.0 0.0 3.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein Metal_resist PF13801.6 PVD36402.1 - 6.6 6.9 11.8 0.69 10.1 0.3 3.0 3 0 0 3 3 3 0 Heavy-metal resistance DPPIV_N PF00930.21 PVD36403.1 - 3.3e-65 220.2 0.8 4.5e-65 219.7 0.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 PVD36403.1 - 2.7e-27 95.6 3.5 2.2e-25 89.4 0.2 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PVD36403.1 - 7.4e-09 35.6 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 PVD36403.1 - 0.00056 20.6 0.1 0.0012 19.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 PVD36403.1 - 0.0022 17.7 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Putative esterase AXE1 PF05448.12 PVD36403.1 - 0.041 12.5 0.0 0.13 10.9 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PVD36403.1 - 0.047 13.5 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD36403.1 - 0.21 10.8 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_32 PF13679.6 PVD36404.1 - 4.7e-26 91.7 12.0 1.5e-14 54.3 0.3 2.9 2 1 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 PVD36404.1 - 0.047 13.4 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PVD36404.1 - 0.14 11.9 0.9 0.4 10.5 0.1 2.2 3 0 0 3 3 3 0 Methyltransferase domain UvrB PF12344.8 PVD36404.1 - 0.21 11.4 3.5 6.1 6.8 0.6 2.7 2 0 0 2 2 2 0 Ultra-violet resistance protein B NIP_1 PF08995.10 PVD36404.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.6 2 1 0 2 2 2 0 Necrosis inducing protein-1 Ank_2 PF12796.7 PVD36405.1 - 8.6e-29 100.0 0.0 3e-17 63.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD36405.1 - 3.4e-25 88.1 0.4 5.7e-11 42.7 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PITH PF06201.13 PVD36405.1 - 5.6e-25 88.3 0.0 1.3e-24 87.1 0.0 1.7 1 0 0 1 1 1 1 PITH domain Ank PF00023.30 PVD36405.1 - 1.3e-21 76.0 3.7 4.6e-07 30.0 0.1 5.4 6 0 0 6 6 5 3 Ankyrin repeat Ank_3 PF13606.6 PVD36405.1 - 1.4e-20 71.2 0.0 6.3e-05 23.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PVD36405.1 - 1.2e-17 63.8 0.1 3.2e-06 27.3 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Thioredoxin PF00085.20 PVD36405.1 - 0.004 17.1 0.1 0.0093 15.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin DUF812 PF05667.11 PVD36405.1 - 0.014 14.3 3.3 0.018 13.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LegC3_N PF18654.1 PVD36405.1 - 0.03 13.6 3.3 0.047 12.9 3.3 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Thioredoxin_2 PF13098.6 PVD36405.1 - 0.047 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Cwf_Cwc_15 PF04889.12 PVD36405.1 - 0.058 13.1 5.4 0.099 12.4 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4140 PF13600.6 PVD36405.1 - 0.11 12.9 10.5 0.031 14.7 4.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4449 PF14613.6 PVD36405.1 - 0.19 11.8 3.1 0.36 10.9 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) GrpE PF01025.19 PVD36405.1 - 0.26 10.9 7.8 0.64 9.7 7.8 1.6 1 0 0 1 1 1 0 GrpE Bap31_Bap29_C PF18035.1 PVD36405.1 - 5.1 7.2 8.7 7.9 6.6 4.9 2.5 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1500 PF07389.12 PVD36406.1 - 0.09 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) p450 PF00067.22 PVD36407.1 - 8.5e-81 272.0 0.0 2.2e-71 241.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 LPMO_10 PF03067.15 PVD36409.1 - 1.6e-14 55.1 0.2 2.6e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TMEM154 PF15102.6 PVD36410.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PVD36410.1 - 0.031 15.2 0.0 0.063 14.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 PVD36410.1 - 0.075 13.0 0.7 0.15 12.1 0.7 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Marek_A PF02124.15 PVD36410.1 - 1.3 8.8 5.2 6.2 6.6 3.8 2.2 1 1 1 2 2 2 0 Marek's disease glycoprotein A p450 PF00067.22 PVD36411.1 - 1.8e-87 294.1 0.0 2.2e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD36412.1 - 4.6e-84 282.8 0.0 6.2e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CobA_CobO_BtuR PF02572.15 PVD36412.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF4690 PF15756.5 PVD36413.1 - 0.0087 16.6 0.9 0.018 15.6 0.9 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 PVD36413.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF1510 PF07423.11 PVD36413.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) zf-C2H2 PF00096.26 PVD36414.1 - 1.4e-32 110.3 30.8 3.2e-05 24.1 0.2 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD36414.1 - 1.5e-31 107.3 32.0 4.3e-07 30.1 0.1 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD36414.1 - 7.2e-27 91.8 32.2 0.00011 22.8 0.2 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PVD36414.1 - 3e-10 40.1 13.7 0.23 11.8 0.1 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD36414.1 - 1.8e-09 37.2 20.8 0.0012 18.6 0.0 6.1 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD36414.1 - 8e-09 35.3 37.3 0.0046 16.9 0.1 7.3 6 2 0 6 6 6 3 C2H2-type zinc finger CpXC PF14353.6 PVD36414.1 - 2.8e-06 27.4 18.6 0.81 9.8 0.1 6.0 2 2 4 6 6 6 1 CpXC protein DZR PF12773.7 PVD36414.1 - 1.5e-05 24.9 21.3 0.037 14.0 6.3 3.4 2 1 1 3 3 3 3 Double zinc ribbon Zn-ribbon_8 PF09723.10 PVD36414.1 - 4.2e-05 23.6 25.3 0.011 15.8 1.4 4.7 1 1 5 6 6 6 3 Zinc ribbon domain zf_UBZ PF18439.1 PVD36414.1 - 4.2e-05 23.0 15.6 2.1 8.0 0.0 6.1 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 PVD36414.1 - 0.0001 22.1 19.5 0.0015 18.4 0.5 4.8 5 1 0 5 5 5 1 zinc-ribbon domain zf-met PF12874.7 PVD36414.1 - 0.0001 22.5 22.1 0.26 11.7 0.1 6.1 6 0 0 6 6 6 1 Zinc-finger of C2H2 type DUF3268 PF11672.8 PVD36414.1 - 0.00011 22.4 7.9 0.25 11.7 0.2 3.5 1 1 1 3 3 3 2 zinc-finger-containing domain Rubredoxin_2 PF18073.1 PVD36414.1 - 0.00018 21.2 23.9 0.98 9.2 0.3 6.1 6 0 0 6 6 6 2 Rubredoxin metal binding domain zf_C2H2_ZHX PF18387.1 PVD36414.1 - 0.00029 20.4 23.7 0.66 9.7 0.1 5.9 1 1 5 6 6 6 2 Zinc-fingers and homeoboxes C2H2 finger domain Elf1 PF05129.13 PVD36414.1 - 0.00072 19.6 17.4 0.019 15.0 0.2 3.6 1 1 3 4 4 4 2 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 PVD36414.1 - 0.00092 19.9 15.2 0.1 13.4 0.4 3.5 1 1 3 4 4 4 2 zinc-ribbon family zf-HYPF PF07503.12 PVD36414.1 - 0.0012 18.6 0.2 0.0012 18.6 0.2 4.7 4 2 0 4 4 4 1 HypF finger zf-C2HE PF16278.5 PVD36414.1 - 0.002 18.6 30.4 0.34 11.4 2.1 5.8 1 1 4 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 PVD36414.1 - 0.0021 18.0 15.9 0.17 11.9 0.3 3.6 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 PVD36414.1 - 0.0078 16.0 23.7 0.014 15.1 0.8 5.0 5 1 0 5 5 5 1 zinc-ribbon domain GAGA PF09237.11 PVD36414.1 - 0.016 15.0 13.7 0.021 14.6 0.1 4.1 1 1 4 5 5 5 0 GAGA factor zf-trcl PF13451.6 PVD36414.1 - 0.017 15.0 28.0 0.28 11.1 0.8 5.9 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-RING_7 PF02591.15 PVD36414.1 - 0.067 13.4 12.0 8.5 6.7 0.0 5.4 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-Sec23_Sec24 PF04810.15 PVD36414.1 - 0.074 13.1 18.2 4 7.6 0.2 5.3 4 2 0 4 4 4 0 Sec23/Sec24 zinc finger zf-AN1 PF01428.16 PVD36414.1 - 0.076 13.2 27.4 6.2 7.1 1.3 6.1 5 1 1 6 6 6 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 PVD36414.1 - 0.13 12.0 0.3 0.13 12.0 0.3 8.4 8 2 0 8 8 8 0 C2H2-type zinc-finger domain DNA_RNApol_7kD PF03604.13 PVD36414.1 - 0.22 11.2 17.4 9.3 6.0 0.0 5.8 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.12 PVD36414.1 - 0.24 11.7 20.5 0.29 11.4 2.1 4.2 1 1 4 5 5 5 0 TFIIH C1-like domain GATA PF00320.27 PVD36414.1 - 0.33 10.6 14.0 2.2 8.0 0.3 5.1 5 1 1 6 6 5 0 GATA zinc finger PHD PF00628.29 PVD36414.1 - 0.33 10.9 23.1 1.9 8.4 2.0 4.4 3 2 1 4 4 4 0 PHD-finger zf-C2H2_3rep PF18868.1 PVD36414.1 - 0.33 11.6 19.1 43 4.8 0.1 4.8 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 PVD36414.1 - 0.61 10.3 25.4 17 5.7 4.7 4.8 1 1 3 4 4 4 0 LIM domain PHD_2 PF13831.6 PVD36414.1 - 0.67 9.6 20.0 26 4.5 0.1 6.3 5 1 1 6 6 6 0 PHD-finger Prok-RING_1 PF14446.6 PVD36414.1 - 1.3 9.0 18.8 4 7.4 0.9 5.6 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 PVD36414.1 - 1.3 9.0 24.8 13 5.8 3.8 5.1 1 1 5 6 6 6 0 Putative transposase DNA-binding domain XPA_N PF01286.18 PVD36414.1 - 1.5 9.0 27.0 6.2 7.0 0.1 5.7 6 0 0 6 6 6 0 XPA protein N-terminal Rpr2 PF04032.16 PVD36414.1 - 2 8.8 16.1 0.73 10.2 0.4 3.8 2 1 2 4 4 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.7 PVD36414.1 - 2.8 8.3 21.7 5.2 7.5 0.2 4.8 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 PVD36414.1 - 3.4 6.7 17.5 24 4.0 0.1 5.1 1 1 2 3 3 3 0 Putative actin-like family zf-C2H2_9 PF16293.5 PVD36414.1 - 3.4 7.6 10.1 14 5.6 0.1 3.9 5 0 0 5 5 3 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 PVD36414.1 - 5.8 6.5 15.6 1.4 8.5 0.2 4.4 4 2 0 4 4 4 0 TFIIB zinc-binding Cytochrom_CIII PF02085.16 PVD36414.1 - 7.6 6.9 22.6 14 6.1 14.0 2.7 1 1 2 3 3 3 0 Class III cytochrome C family zf-RRN7 PF11781.8 PVD36414.1 - 8.9 6.1 20.1 3.6 7.3 0.3 5.6 6 0 0 6 6 6 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_4 PF13894.6 PVD36415.1 - 2.2e-09 37.4 27.2 0.00045 20.8 0.7 5.6 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD36415.1 - 4.7e-08 33.1 27.3 1.8e-05 24.9 1.0 4.6 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD36415.1 - 1.9e-07 31.2 23.6 0.00077 19.8 0.6 5.1 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD36415.1 - 2.2e-05 24.6 1.8 0.0096 16.2 0.9 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 PVD36415.1 - 9.3e-05 22.1 10.8 0.00048 19.8 0.7 4.7 6 0 0 6 6 5 2 zinc-finger C2H2-type zf-met PF12874.7 PVD36415.1 - 0.00064 20.0 3.2 0.35 11.3 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PVD36415.1 - 0.0088 16.0 0.2 0.0088 16.0 0.2 4.8 5 0 0 5 5 5 2 C2H2-type zinc finger GAGA PF09237.11 PVD36415.1 - 0.032 14.0 5.4 0.54 10.1 0.2 2.9 1 1 1 2 2 2 0 GAGA factor ALF PF03752.13 PVD36415.1 - 0.2 11.7 0.4 0.39 10.7 0.4 1.5 1 0 0 1 1 1 0 Short repeats of unknown function zf-H2C2_5 PF13909.6 PVD36415.1 - 0.4 10.5 0.1 0.4 10.5 0.1 4.4 5 0 0 5 5 4 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 PVD36415.1 - 0.64 10.4 10.9 0.14 12.5 2.2 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 PVD36415.1 - 1.8 8.9 14.5 0.66 10.4 0.1 3.8 2 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PVD36416.1 - 1.2e-07 31.7 27.6 0.00012 22.3 3.6 4.6 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36416.1 - 1.4e-07 31.7 25.7 0.00021 21.9 0.4 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-BED PF02892.15 PVD36416.1 - 6.7e-06 26.0 1.7 6.7e-06 26.0 1.7 3.7 2 1 1 3 3 3 1 BED zinc finger zf-H2C2_2 PF13465.6 PVD36416.1 - 7.8e-06 26.1 16.9 0.0061 16.9 0.4 5.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 PVD36416.1 - 0.00016 21.3 6.7 0.059 13.2 0.0 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PVD36416.1 - 0.00017 21.8 1.5 0.95 9.8 0.4 3.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.6 PVD36416.1 - 0.0014 18.4 0.8 0.0014 18.4 0.8 2.9 3 0 0 3 3 2 1 zinc-ribbon domain zf-C2HE PF16278.5 PVD36416.1 - 0.1 13.1 9.1 0.05 14.0 1.7 3.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger CAP_N PF01213.19 PVD36416.1 - 0.67 9.4 11.3 0.027 14.0 5.3 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FYVE PF01363.21 PVD36416.1 - 2.4 8.4 11.0 1.2 9.3 1.2 3.4 3 0 0 3 3 3 0 FYVE zinc finger DZR PF12773.7 PVD36416.1 - 3.8 7.6 13.9 0.48 10.5 0.4 3.2 3 0 0 3 3 3 0 Double zinc ribbon LPMO_10 PF03067.15 PVD36417.1 - 9.6e-19 68.8 2.0 7.3e-18 65.9 1.0 2.0 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-CHY PF05495.12 PVD36417.1 - 5.6 7.5 10.6 2.1 8.9 7.0 2.1 2 0 0 2 2 2 0 CHY zinc finger FoP_duplication PF13865.6 PVD36418.1 - 7.4e-18 64.9 16.7 7.4e-18 64.9 16.7 4.7 2 1 2 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 TPH PF13868.6 PVD36419.1 - 3e-82 276.0 160.3 3e-82 276.0 160.3 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain LRR_6 PF13516.6 PVD36420.1 - 1.5e-15 55.8 7.7 0.0014 18.5 0.0 9.1 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 PVD36420.1 - 6.6e-13 48.6 1.9 0.0009 19.6 0.6 6.5 2 2 7 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD36420.1 - 5.2e-05 23.2 4.9 56 4.9 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD36420.1 - 0.0015 18.3 2.9 0.055 13.2 0.6 3.5 2 2 0 2 2 2 1 Leucine rich repeat Pkinase_Tyr PF07714.17 PVD36421.1 - 1e-94 316.6 0.0 1.9e-94 315.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36421.1 - 7.3e-49 166.5 0.2 2.2e-48 164.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 PVD36421.1 - 2e-13 50.2 0.3 1.6e-12 47.4 0.2 2.6 2 0 0 2 2 2 1 SH2 domain FCH PF00611.23 PVD36421.1 - 4.5e-08 33.3 0.3 4.5e-08 33.3 0.3 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RRP36 PF06102.12 PVD36421.1 - 1 9.3 15.2 0.56 10.2 6.3 2.4 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 OmpH PF03938.14 PVD36421.1 - 1.9 8.8 22.1 0.63 10.4 1.9 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 PVD36421.1 - 3.7 7.0 12.5 1 8.9 1.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit RVT_1 PF00078.27 PVD36422.1 - 1.4e-08 34.6 0.1 2.4e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mustang PF15682.5 PVD36422.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 TPR_12 PF13424.6 PVD36423.1 - 1.6e-31 108.4 14.0 3.4e-07 30.5 0.0 6.2 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 PVD36423.1 - 1.5e-11 43.7 6.3 0.24 11.3 0.4 7.1 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 PVD36423.1 - 1.6e-08 34.1 17.5 0.12 12.7 0.2 7.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD36423.1 - 2.4e-08 33.5 5.6 0.0039 17.0 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD36423.1 - 7.7e-07 28.8 11.3 0.19 11.9 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD36423.1 - 4.4e-06 27.1 4.6 3.7 8.6 0.5 6.1 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PVD36423.1 - 8e-06 26.3 1.3 0.33 11.5 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD36423.1 - 8.1e-06 25.4 2.0 0.00059 19.3 0.3 2.3 2 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 PVD36423.1 - 9.8e-05 22.1 5.3 0.57 10.3 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 PVD36423.1 - 0.0017 18.8 3.1 3.3 8.6 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD36423.1 - 0.0018 18.5 10.5 0.81 10.0 0.1 5.8 5 2 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PVD36423.1 - 0.083 13.3 1.7 1.2e+02 3.4 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD36423.1 - 0.95 10.2 5.1 1.3e+02 3.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ERAP1_C PF11838.8 PVD36424.1 - 1.7e-69 234.8 0.4 3.3e-69 233.9 0.4 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD36424.1 - 3.3e-35 121.6 6.8 9.3e-28 97.3 1.3 3.4 1 1 2 3 3 3 3 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD36424.1 - 3.9e-27 95.6 0.4 4.1e-19 69.5 0.2 2.5 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain I-set PF07679.16 PVD36425.1 - 1.9e-29 101.6 0.0 1.9e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36425.1 - 3.3e-25 88.5 3.0 3.1e-13 50.1 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD36425.1 - 5.4e-23 81.1 0.2 2.8e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD36425.1 - 2.3e-15 56.5 0.1 3e-08 33.7 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain LCCL PF03815.19 PVD36425.1 - 3.9e-10 39.7 0.2 3.7e-09 36.6 0.2 2.1 2 0 0 2 2 2 1 LCCL domain V-set PF07686.17 PVD36425.1 - 1.2e-07 31.9 3.1 0.17 12.1 0.0 3.9 2 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD36425.1 - 5.2e-05 22.7 0.0 0.079 12.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 PVD36425.1 - 0.0022 18.0 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 PVD36425.1 - 0.008 16.2 0.3 0.46 10.6 0.0 2.8 2 2 0 2 2 2 1 C17orf99 Ig domain I-set PF07679.16 PVD36426.1 - 5.6e-20 71.2 0.1 2e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36426.1 - 1.3e-17 64.1 2.7 1.8e-09 38.1 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD36426.1 - 2.1e-11 44.0 1.7 2.5e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD36426.1 - 8.3e-09 35.5 1.3 1.2e-05 25.4 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD36426.1 - 2.3e-06 27.7 1.4 0.089 13.0 0.2 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD36426.1 - 4.8e-06 26.6 1.3 0.0019 18.2 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain RhoGAP PF00620.27 PVD36427.1 - 6.4e-11 42.3 1.8 6.4e-11 42.3 1.8 2.6 2 1 0 2 2 2 1 RhoGAP domain BAF1_ABF1 PF04684.13 PVD36427.1 - 0.0042 16.2 5.2 0.0042 16.2 5.2 3.4 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor CPW_WPC PF09717.10 PVD36429.1 - 2.8 9.0 4.4 4.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Glyco_transf_11 PF01531.16 PVD36430.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Rdx PF10262.9 PVD36431.1 - 2.7e-09 37.1 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family zf-RING_2 PF13639.6 PVD36432.1 - 7.6e-15 55.0 6.6 7.6e-15 55.0 6.6 2.8 3 0 0 3 3 1 1 Ring finger domain zf-RING_11 PF17123.5 PVD36432.1 - 3.2e-10 39.6 3.3 3.2e-10 39.6 3.3 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD36432.1 - 2.7e-09 36.7 6.1 2.7e-09 36.7 6.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36432.1 - 1.7e-07 31.0 4.9 4.1e-07 29.8 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36432.1 - 2.2e-07 30.6 5.7 2.2e-07 30.6 5.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36432.1 - 2.4e-07 30.6 4.2 7.7e-07 29.0 4.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD36432.1 - 3.8e-07 30.3 8.0 3.8e-07 30.3 8.0 3.3 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD36432.1 - 2e-05 24.5 2.5 2e-05 24.5 2.5 2.3 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD36432.1 - 0.0002 21.2 5.8 0.00055 19.7 5.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD36432.1 - 0.0094 16.0 2.9 0.0094 16.0 2.9 2.5 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 PVD36432.1 - 0.083 12.8 4.8 2.6 8.1 1.1 3.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 PVD36432.1 - 0.28 11.4 4.4 0.93 9.7 4.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 PVD36432.1 - 0.46 10.3 4.4 1.1 9.1 4.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 PVD36432.1 - 2 8.6 11.1 0.37 10.9 6.3 2.3 2 0 0 2 2 2 0 RING-variant domain Glyco_tran_28_C PF04101.16 PVD36433.1 - 0.00062 19.8 0.0 0.00073 19.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Epimerase PF01370.21 PVD36434.1 - 5.4e-22 78.4 0.0 7.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PVD36434.1 - 1.3e-08 34.6 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 PVD36434.1 - 2.2e-07 30.2 0.0 2.9e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PVD36434.1 - 8.7e-05 22.5 0.0 0.00021 21.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PVD36434.1 - 0.0038 16.4 0.1 0.058 12.6 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 PVD36434.1 - 0.051 12.7 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein XG_FTase PF03254.13 PVD36435.1 - 0.014 14.1 0.1 3.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase MCC-bdg_PDZ PF10506.9 PVD36436.1 - 1.8e-32 111.1 12.0 4.2e-20 71.5 3.1 4.8 4 2 1 5 5 5 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Gp-FAR-1 PF05823.12 PVD36436.1 - 0.044 14.2 2.5 0.14 12.6 2.5 1.8 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.12 PVD36436.1 - 0.16 12.0 4.7 3.8 7.5 0.6 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BBP1_C PF15272.6 PVD36436.1 - 1.4 8.7 23.9 1.2 9.0 1.1 3.5 2 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal Mis14 PF08641.12 PVD36436.1 - 6.4 7.1 10.8 2.8 8.3 2.9 3.5 2 1 1 3 3 3 0 Kinetochore protein Mis14 like Tropomodulin PF03250.14 PVD36437.1 - 6.1e-39 133.3 4.0 6.1e-39 133.3 4.0 1.8 2 0 0 2 2 2 1 Tropomodulin PRA-PH PF01503.17 PVD36437.1 - 0.035 14.5 3.6 15 6.1 0.1 4.2 3 1 0 3 3 3 0 Phosphoribosyl-ATP pyrophosphohydrolase AAA_6 PF12774.7 PVD36438.1 - 1.1e-166 553.7 0.4 1.9e-165 549.7 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD36438.1 - 5.8e-110 368.1 8.8 4.6e-58 197.2 0.0 4.7 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD36438.1 - 1.2e-109 365.6 0.0 2.5e-108 361.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PVD36438.1 - 6.2e-103 344.2 0.8 8.3e-101 337.2 0.0 3.5 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PVD36438.1 - 2.5e-96 321.1 0.3 7.7e-94 312.9 0.3 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD36438.1 - 6.9e-81 270.1 2.1 1.5e-73 246.2 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 PVD36438.1 - 7.5e-57 192.9 18.9 7.5e-57 192.9 18.9 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PVD36438.1 - 4.4e-43 146.2 0.0 2.6e-42 143.6 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 PVD36438.1 - 2.5e-36 125.0 0.0 1e-34 119.7 0.0 2.9 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD36438.1 - 1.4e-22 80.2 0.0 2.6e-09 37.2 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PVD36438.1 - 2.8e-22 79.2 2.1 1.7e-21 76.6 0.1 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD36438.1 - 5.9e-20 71.3 2.6 6e-20 71.3 0.2 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 PVD36438.1 - 3.5e-12 46.9 1.9 0.054 13.9 0.0 6.2 5 1 1 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD36438.1 - 7.7e-10 39.4 0.2 0.79 10.1 0.0 5.9 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 PVD36438.1 - 2e-09 38.1 0.6 0.033 14.7 0.0 5.5 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 PVD36438.1 - 4.9e-09 36.6 1.2 0.011 16.1 0.0 4.9 5 0 0 5 5 3 2 AAA domain T2SSE PF00437.20 PVD36438.1 - 9.7e-09 34.7 0.8 0.011 14.8 0.0 4.2 5 0 0 5 5 4 2 Type II/IV secretion system protein RNA_helicase PF00910.22 PVD36438.1 - 7e-07 29.6 0.2 0.23 11.8 0.0 4.4 4 0 0 4 4 3 2 RNA helicase Sigma54_activat PF00158.26 PVD36438.1 - 2.1e-06 27.6 0.5 0.059 13.1 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain TsaE PF02367.17 PVD36438.1 - 1.1e-05 25.4 0.5 0.065 13.2 0.0 4.7 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 PVD36438.1 - 0.00016 20.4 0.9 0.095 11.3 0.0 3.1 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) ABC_tran PF00005.27 PVD36438.1 - 0.00082 19.9 0.3 0.48 10.9 0.1 4.4 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 PVD36438.1 - 0.0012 19.0 1.1 0.29 11.3 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_29 PF13555.6 PVD36438.1 - 0.002 17.9 0.7 1.9 8.3 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 PVD36438.1 - 0.002 17.9 2.9 2.9 7.6 0.0 4.6 5 0 0 5 5 4 1 AAA domain Cytidylate_kin PF02224.18 PVD36438.1 - 0.002 17.9 0.0 3.1 7.5 0.0 3.7 3 0 0 3 3 3 1 Cytidylate kinase NACHT PF05729.12 PVD36438.1 - 0.0022 17.9 0.6 1.7 8.5 0.0 4.7 5 0 0 5 5 4 1 NACHT domain Rad17 PF03215.15 PVD36438.1 - 0.0039 17.1 0.2 0.4 10.6 0.0 3.3 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 PVD36438.1 - 0.017 14.8 0.0 0.56 9.8 0.0 3.3 2 2 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 PVD36438.1 - 0.02 14.2 0.2 32 3.7 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 PVD36438.1 - 0.021 15.1 3.2 32 4.8 0.0 4.8 5 0 0 5 5 3 0 AAA domain RsgA_GTPase PF03193.16 PVD36438.1 - 0.022 14.6 0.3 2.5 8.0 0.0 3.5 3 0 0 3 3 3 0 RsgA GTPase BORCS7 PF16088.5 PVD36438.1 - 0.023 15.0 1.0 12 6.2 0.0 3.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DEAD PF00270.29 PVD36438.1 - 0.023 14.5 0.0 0.32 10.7 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 PVD36438.1 - 0.024 14.9 0.8 8.1 6.7 0.0 4.3 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 PVD36438.1 - 0.026 13.9 1.0 0.39 10.1 0.0 2.9 4 0 0 4 4 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 PVD36438.1 - 0.026 13.4 0.2 8.1 5.2 0.0 3.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 PVD36438.1 - 0.058 13.0 4.7 0.46 10.1 0.1 3.5 4 0 0 4 4 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 PVD36438.1 - 0.071 12.3 0.5 13 4.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 PVD36438.1 - 0.081 12.8 9.5 0.55 10.1 0.1 4.7 4 1 0 4 4 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 PVD36438.1 - 0.093 12.5 0.1 0.73 9.6 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 PVD36438.1 - 0.22 11.2 1.1 26 4.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 PVD36438.1 - 0.36 10.7 2.1 12 5.7 0.1 3.7 3 0 0 3 3 3 0 NTPase RSS_P20 PF11757.8 PVD36438.1 - 0.55 10.7 4.1 3.9 8.0 0.7 3.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain dNK PF01712.19 PVD36438.1 - 0.65 9.8 3.5 6.9 6.5 0.0 4.0 4 0 0 4 4 3 0 Deoxynucleoside kinase ResIII PF04851.15 PVD36438.1 - 0.74 9.8 6.2 1.1 9.2 0.0 4.0 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit Hyd_WA PF06462.12 PVD36439.1 - 3.9e-09 36.4 28.1 0.013 15.5 0.0 6.8 7 1 0 7 7 7 4 Propeller PK PF00224.21 PVD36440.1 - 9.6e-112 373.3 0.0 1.2e-111 373.0 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PVD36440.1 - 1.7e-26 92.8 0.2 6.8e-26 90.8 0.1 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PVD36440.1 - 0.0038 16.4 0.1 0.0063 15.7 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 PVD36440.1 - 0.047 12.7 0.1 1.6 7.6 0.0 2.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PK PF00224.21 PVD36441.1 - 3.7e-92 308.9 0.5 3.5e-80 269.5 0.0 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 PVD36441.1 - 5.1e-17 62.2 0.2 2.5e-16 60.0 0.2 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PVD36441.1 - 0.0024 17.1 0.1 0.0038 16.4 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ion_trans PF00520.31 PVD36442.1 - 9.4e-31 106.9 7.0 1.3e-30 106.4 7.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD36442.1 - 1.9e-11 43.7 5.6 7.3e-11 41.9 5.6 2.1 1 1 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 PVD36442.1 - 1.7e-10 40.8 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-B_box PF00643.24 PVD36445.1 - 3e-06 27.3 7.8 3e-06 27.3 7.8 3.5 2 1 1 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36445.1 - 8.3e-06 25.6 12.7 8.3e-06 25.6 12.7 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36445.1 - 7.7e-05 22.6 11.9 7.7e-05 22.6 11.9 3.5 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD36445.1 - 9.6e-05 22.2 10.6 9.6e-05 22.2 10.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36445.1 - 9.9e-05 22.6 11.7 9.9e-05 22.6 11.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD36445.1 - 0.00014 21.8 7.7 0.00014 21.8 7.7 3.1 3 2 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36445.1 - 0.00059 19.6 12.7 0.00059 19.6 12.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36445.1 - 0.00094 19.0 13.0 0.00094 19.0 13.0 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD36445.1 - 0.0014 18.8 13.1 0.0014 18.8 13.1 2.8 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING IBR PF01485.21 PVD36445.1 - 0.02 15.1 5.9 0.02 15.1 5.9 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 PVD36445.1 - 0.028 14.7 2.2 0.028 14.7 2.2 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain zf-Sec23_Sec24 PF04810.15 PVD36445.1 - 0.038 14.0 9.0 1.1 9.4 1.8 3.3 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger RNA_POL_M_15KD PF02150.16 PVD36445.1 - 0.41 10.6 0.1 0.41 10.6 0.1 3.7 3 1 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-B_box PF00643.24 PVD36446.1 - 9.9e-09 35.2 9.5 9.9e-09 35.2 9.5 2.2 2 0 0 2 2 2 1 B-box zinc finger IBR PF01485.21 PVD36446.1 - 0.0019 18.4 7.2 0.0019 18.4 7.2 2.0 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-Sec23_Sec24 PF04810.15 PVD36446.1 - 0.0094 16.0 2.5 1.4 9.0 0.6 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Trm112p PF03966.16 PVD36446.1 - 0.045 14.3 1.1 0.045 14.3 1.1 1.8 2 1 0 2 2 2 0 Trm112p-like protein C1_4 PF07975.12 PVD36446.1 - 0.15 12.3 10.8 0.47 10.7 6.3 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain zf-B_box PF00643.24 PVD36447.1 - 1.4e-11 44.3 3.3 1.4e-11 44.3 3.3 3.7 3 1 1 4 4 4 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36447.1 - 3.2e-09 36.5 10.2 3.2e-09 36.5 10.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36447.1 - 3.7e-09 36.5 11.2 3.7e-09 36.5 11.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36447.1 - 4.9e-09 35.9 8.0 4.9e-09 35.9 8.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36447.1 - 5.9e-07 29.5 11.9 5.9e-07 29.5 11.9 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36447.1 - 6.7e-07 29.5 11.2 6.7e-07 29.5 11.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36447.1 - 6.3e-06 25.9 11.2 6.3e-06 25.9 11.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36447.1 - 6.7e-06 26.0 8.8 6.7e-06 26.0 8.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain IBR PF01485.21 PVD36447.1 - 0.0021 18.3 1.6 0.0021 18.3 1.6 3.4 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36447.1 - 0.0024 17.6 3.0 0.0024 17.6 3.0 3.4 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PVD36447.1 - 0.015 15.1 9.9 0.015 15.1 9.9 2.4 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 DUF740 PF05340.12 PVD36447.1 - 0.024 13.4 2.1 0.029 13.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Peptidase_C39 PF03412.15 PVD36447.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family zf-FPG_IleRS PF06827.14 PVD36447.1 - 3 7.8 18.6 13 5.8 0.0 5.3 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zf-B_box PF00643.24 PVD36448.1 - 3.2e-08 33.6 7.4 3.2e-08 33.6 7.4 3.1 2 1 1 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36448.1 - 0.00037 20.6 6.1 0.00037 20.6 6.1 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD36448.1 - 0.00086 19.3 10.3 0.00086 19.3 10.3 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36448.1 - 0.0028 17.5 9.5 0.0028 17.5 9.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.12 PVD36448.1 - 0.003 18.1 2.1 0.0059 17.2 2.1 1.4 1 0 0 1 1 1 1 SlyX zf-RING_5 PF14634.6 PVD36448.1 - 0.0058 16.6 9.3 0.0058 16.6 9.3 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36448.1 - 0.0071 16.7 11.0 0.0071 16.7 11.0 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_4 PF14570.6 PVD36448.1 - 0.0092 15.8 1.9 0.0092 15.8 1.9 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain IBR PF01485.21 PVD36448.1 - 0.02 15.1 11.6 0.026 14.7 3.4 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DegS PF05384.11 PVD36448.1 - 0.023 14.2 0.9 0.032 13.7 0.9 1.3 1 0 0 1 1 1 0 Sensor protein DegS ZapB PF06005.12 PVD36448.1 - 0.056 13.9 0.6 0.056 13.9 0.6 1.5 2 0 0 2 2 1 0 Cell division protein ZapB DUF1664 PF07889.12 PVD36448.1 - 0.072 13.1 0.7 0.1 12.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cdh1_DBD_1 PF18196.1 PVD36448.1 - 0.13 12.6 1.1 0.19 12.1 1.1 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 C1_1 PF00130.22 PVD36448.1 - 1.6 8.7 15.9 1.3 8.9 1.4 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 PVD36448.1 - 4.3 7.3 23.2 0.071 13.0 11.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36449.1 - 1.7e-20 72.7 28.6 1.1e-09 38.1 8.5 5.4 4 0 0 4 4 4 2 RING-type zinc-finger zf-B_box PF00643.24 PVD36449.1 - 7.3e-16 58.0 44.9 2.5e-07 30.7 7.8 6.2 6 2 0 6 6 3 3 B-box zinc finger zf-C3HC4 PF00097.25 PVD36449.1 - 6.8e-14 51.5 28.4 2.5e-08 33.7 9.8 5.4 7 1 0 7 7 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36449.1 - 2.1e-13 49.9 23.0 2.9e-08 33.4 6.8 5.6 5 0 0 5 5 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36449.1 - 1.2e-10 41.5 28.9 1.2e-06 28.8 9.9 5.6 5 1 0 5 5 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36449.1 - 8.7e-10 38.6 28.8 5.7e-06 26.4 10.5 5.8 6 0 0 6 6 5 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD36449.1 - 3.1e-08 33.3 29.0 1.7e-05 24.5 10.0 5.5 6 0 0 6 6 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36449.1 - 3.5e-08 33.3 27.2 3e-05 23.9 9.8 5.8 5 0 0 5 5 5 2 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36449.1 - 7.5e-07 28.9 25.4 9.4e-05 22.2 8.2 5.2 5 1 1 6 6 3 2 Prokaryotic RING finger family 4 COG5 PF10392.9 PVD36449.1 - 6.5e-06 26.3 4.8 0.03 14.5 0.1 3.2 3 0 0 3 3 3 2 Golgi transport complex subunit 5 DUF3206 PF11472.8 PVD36449.1 - 4.4e-05 23.5 0.0 0.34 10.9 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3206) EMP24_GP25L PF01105.24 PVD36449.1 - 0.0007 19.6 1.2 0.21 11.5 0.0 2.8 3 0 0 3 3 3 1 emp24/gp25L/p24 family/GOLD DegS PF05384.11 PVD36449.1 - 0.00076 19.0 15.3 0.073 12.6 1.0 3.3 3 0 0 3 3 3 3 Sensor protein DegS La PF05383.17 PVD36449.1 - 0.0036 17.3 2.5 14 5.8 0.0 3.6 3 0 0 3 3 3 0 La domain Herpes_UL21 PF03252.13 PVD36449.1 - 0.0062 15.3 0.0 1.1 8.0 0.0 3.0 3 0 0 3 3 3 1 Herpesvirus UL21 IBR PF01485.21 PVD36449.1 - 0.014 15.6 58.4 0.14 12.4 5.6 7.2 3 2 2 5 5 5 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36449.1 - 0.018 14.8 6.6 0.018 14.8 6.6 6.3 5 2 1 6 6 6 0 RING/Ubox like zinc-binding domain Tai4 PF16695.5 PVD36449.1 - 0.02 15.4 1.9 2.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein RE_SinI PF09570.10 PVD36449.1 - 0.028 13.7 0.0 0.35 10.1 0.0 2.5 3 0 0 3 3 3 0 SinI restriction endonuclease DDE_Tnp_IS1 PF03400.13 PVD36449.1 - 0.039 14.3 0.4 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 IS1 transposase Fzo_mitofusin PF04799.13 PVD36449.1 - 0.093 12.3 14.9 2.6 7.6 0.7 3.2 3 0 0 3 3 3 0 fzo-like conserved region CLZ PF16526.5 PVD36449.1 - 0.097 13.0 12.6 0.69 10.3 0.7 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TrmB PF01978.19 PVD36449.1 - 0.11 12.4 0.1 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB PEP-utilisers_N PF05524.13 PVD36449.1 - 0.13 12.4 8.0 6.4 7.0 0.2 3.4 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Pox_E10 PF04805.12 PVD36449.1 - 0.14 12.0 4.3 2.7 7.9 0.4 3.6 2 0 0 2 2 2 0 E10-like protein conserved region Baculo_PEP_C PF04513.12 PVD36449.1 - 0.15 12.1 0.3 19 5.3 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD-3 PF09765.9 PVD36449.1 - 0.19 11.1 3.5 1.8 7.9 0.3 2.3 2 0 0 2 2 2 0 WD-repeat region Apolipoprotein PF01442.18 PVD36449.1 - 0.23 11.3 9.8 8 6.3 0.2 2.9 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Muted PF14942.6 PVD36449.1 - 0.38 11.1 14.7 3.2 8.1 0.8 3.3 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Spc24 PF08286.11 PVD36449.1 - 0.45 10.8 5.2 2.6 8.3 0.0 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 EzrA PF06160.12 PVD36449.1 - 0.47 8.6 9.8 0.38 8.9 0.5 3.1 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Catalase-rel PF06628.12 PVD36449.1 - 0.93 9.8 2.9 9.1 6.6 0.0 3.4 4 0 0 4 4 3 0 Catalase-related immune-responsive DUF1664 PF07889.12 PVD36449.1 - 1.4 9.0 7.5 16 5.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Init_tRNA_PT PF04179.12 PVD36449.1 - 1.9 8.8 4.8 1.6 9.1 0.1 2.9 3 0 0 3 3 3 0 Rit1 DUSP-like domain zinc_ribbon_5 PF13719.6 PVD36449.1 - 2.4 8.0 0.0 2.4 8.0 0.0 5.9 7 0 0 7 7 6 0 zinc-ribbon domain FlxA PF14282.6 PVD36449.1 - 5.9 6.9 8.7 3.4 7.7 0.5 3.1 3 0 0 3 3 3 0 FlxA-like protein zf-B_box PF00643.24 PVD36450.1 - 3.5e-09 36.7 5.6 3.5e-09 36.7 5.6 3.5 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36450.1 - 1.1e-08 34.8 9.0 1.1e-08 34.8 9.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36450.1 - 1.2e-08 34.9 7.3 1.2e-08 34.9 7.3 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36450.1 - 1.8e-07 30.9 7.9 1.8e-07 30.9 7.9 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36450.1 - 9.9e-07 28.6 22.0 1.8e-06 27.8 8.4 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36450.1 - 2.3e-06 27.8 9.2 2.3e-06 27.8 9.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36450.1 - 6.3e-06 25.9 8.9 6.3e-06 25.9 8.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36450.1 - 1.1e-05 25.5 10.0 1.1e-05 25.5 10.0 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36450.1 - 0.00067 19.5 8.6 0.00067 19.5 8.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD36450.1 - 0.00078 19.2 16.3 0.0033 17.2 3.0 3.3 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain Peptidase_C39 PF03412.15 PVD36450.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 Peptidase C39 family zinc_ribbon_5 PF13719.6 PVD36450.1 - 0.094 12.5 4.0 13 5.6 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 PVD36450.1 - 0.17 12.1 22.7 0.025 14.8 8.2 3.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 PVD36450.1 - 1.6 9.1 19.6 0.06 13.6 3.0 3.9 2 1 1 3 3 3 0 TFIIH C1-like domain HscB_4_cys PF18256.1 PVD36450.1 - 4.1 7.3 9.9 2.5 8.0 1.4 3.6 3 1 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-RING_UBOX PF13445.6 PVD36451.1 - 6.5e-10 38.9 9.7 6.5e-10 38.9 9.7 3.9 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36451.1 - 1.3e-08 34.6 11.1 1.3e-08 34.6 11.1 3.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36451.1 - 1.3e-08 34.8 7.8 1.3e-08 34.8 7.8 3.5 2 1 0 2 2 1 1 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD36451.1 - 1.4e-08 34.4 7.7 1.4e-08 34.4 7.7 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36451.1 - 1.9e-07 31.3 11.2 1.9e-07 31.3 11.2 3.3 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36451.1 - 5.1e-07 29.7 10.3 5.1e-07 29.7 10.3 3.1 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD36451.1 - 2.7e-06 27.1 11.4 2.7e-06 27.1 11.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36451.1 - 2.2e-05 24.3 10.2 2.2e-05 24.3 10.2 3.1 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36451.1 - 8.8e-05 22.3 9.5 8.8e-05 22.3 9.5 3.0 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36451.1 - 0.003 17.8 6.2 0.003 17.8 6.2 3.7 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36451.1 - 0.0081 15.9 5.5 0.0081 15.9 5.5 3.2 2 2 1 3 3 3 1 RING/Ubox like zinc-binding domain COG5 PF10392.9 PVD36451.1 - 0.022 14.9 0.5 0.034 14.3 0.5 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 EMP24_GP25L PF01105.24 PVD36451.1 - 0.056 13.4 2.2 0.07 13.1 2.2 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.9 PVD36451.1 - 0.13 12.4 3.9 0.12 12.6 2.4 1.7 2 0 0 2 2 2 0 Haemolysin XhlA zf-piccolo PF05715.13 PVD36451.1 - 6.7 6.9 16.6 0.46 10.7 2.8 2.8 2 1 0 2 2 2 0 Piccolo Zn-finger zf-RING_UBOX PF13445.6 PVD36452.1 - 5.4e-10 39.1 9.4 5.4e-10 39.1 9.4 2.6 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36452.1 - 3.6e-09 36.3 10.7 3.6e-09 36.3 10.7 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36452.1 - 2.6e-08 33.6 7.7 2.6e-08 33.6 7.7 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36452.1 - 3.9e-08 33.3 8.0 3.9e-08 33.3 8.0 4.2 2 2 2 4 4 4 1 B-box zinc finger zf-RING_2 PF13639.6 PVD36452.1 - 1.9e-07 31.3 11.0 1.9e-07 31.3 11.0 3.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36452.1 - 3.5e-07 30.3 10.2 3.5e-07 30.3 10.2 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD36452.1 - 2.9e-06 27.0 11.3 2.9e-06 27.0 11.3 3.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36452.1 - 1.8e-05 24.6 10.1 1.8e-05 24.6 10.1 3.1 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36452.1 - 9.3e-05 22.2 9.5 9.3e-05 22.2 9.5 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD36452.1 - 0.011 15.5 6.0 0.011 15.5 6.0 3.4 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF3206 PF11472.8 PVD36452.1 - 0.06 13.3 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) zf-RING_11 PF17123.5 PVD36452.1 - 1.8 8.4 15.6 0.078 12.7 8.0 2.8 2 1 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 PVD36452.1 - 3.8 7.8 28.1 1.6 9.0 11.5 4.5 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 PVD36453.1 - 3.9e-09 36.5 7.9 3.9e-09 36.5 7.9 3.5 5 0 0 5 5 5 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36453.1 - 3e-08 33.4 8.1 3e-08 33.4 8.1 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36453.1 - 1.1e-07 31.6 5.7 1.1e-07 31.6 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36453.1 - 8e-07 29.0 8.0 8e-07 29.0 8.0 2.4 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD36453.1 - 8.6e-06 26.0 8.8 8.6e-06 26.0 8.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PVD36453.1 - 9.2e-06 25.5 7.0 9.2e-06 25.5 7.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36453.1 - 1.3e-05 24.9 8.6 1.3e-05 24.9 8.6 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36453.1 - 4.9e-05 23.4 10.6 4.9e-05 23.4 10.6 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36453.1 - 0.00024 20.9 7.9 0.00024 20.9 7.9 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36453.1 - 0.0016 18.6 13.6 0.08 13.2 6.8 2.9 1 1 1 2 2 2 2 IBR domain, a half RING-finger domain Prot_inhib_II PF02428.15 PVD36453.1 - 0.029 14.8 2.9 0.029 14.8 2.9 2.3 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family DUF3336 PF11815.8 PVD36453.1 - 0.17 11.6 0.3 14 5.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3336) HscB_4_cys PF18256.1 PVD36453.1 - 8.5 6.3 8.6 5.6 6.9 1.5 3.2 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-C3HC4 PF00097.25 PVD36454.1 - 4e-09 36.2 10.3 4e-09 36.2 10.3 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36454.1 - 4.9e-09 35.9 7.6 4.9e-09 35.9 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36454.1 - 2e-08 34.1 8.5 2e-08 34.1 8.5 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 PVD36454.1 - 2.3e-08 34.0 9.9 2.3e-08 34.0 9.9 3.9 3 1 0 3 3 2 1 B-box zinc finger zf-RING_2 PF13639.6 PVD36454.1 - 6.1e-07 29.7 10.6 6.1e-07 29.7 10.6 2.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36454.1 - 1.5e-06 28.2 10.1 1.5e-06 28.2 10.1 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36454.1 - 8.2e-06 25.7 9.3 8.2e-06 25.7 9.3 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36454.1 - 9.4e-06 25.4 10.1 9.4e-06 25.4 10.1 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36454.1 - 8.5e-05 22.3 7.7 8.5e-05 22.3 7.7 2.9 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36454.1 - 0.00039 20.6 8.5 0.00039 20.6 8.5 3.4 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 PVD36454.1 - 0.024 14.5 4.1 0.024 14.5 4.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RE_SinI PF09570.10 PVD36454.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 SinI restriction endonuclease zf-RING_4 PF14570.6 PVD36454.1 - 2.6 7.9 23.5 0.41 10.5 8.7 3.3 2 2 2 4 4 4 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PVD36455.1 - 2.5e-09 36.8 7.5 2.5e-09 36.8 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36455.1 - 7.6e-09 35.5 9.2 7.6e-09 35.5 9.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36455.1 - 6.5e-08 32.3 10.6 6.5e-08 32.3 10.6 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36455.1 - 3.3e-07 30.3 9.8 3.3e-07 30.3 9.8 3.8 4 1 1 5 5 5 1 B-box zinc finger zf-RING_2 PF13639.6 PVD36455.1 - 7.2e-07 29.5 10.9 7.2e-07 29.5 10.9 2.8 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36455.1 - 2.3e-06 27.7 10.5 2.3e-06 27.7 10.5 2.9 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36455.1 - 1.1e-05 25.2 9.1 1.1e-05 25.2 9.1 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD36455.1 - 1.1e-05 25.3 9.7 1.1e-05 25.3 9.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36455.1 - 1.7e-05 24.5 11.0 1.7e-05 24.5 11.0 2.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Sipho_Gp157 PF05565.11 PVD36455.1 - 2.5e-05 24.3 1.7 3.8e-05 23.7 1.7 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 IBR PF01485.21 PVD36455.1 - 0.018 15.3 7.6 0.018 15.3 7.6 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain RE_SinI PF09570.10 PVD36455.1 - 0.043 13.0 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 SinI restriction endonuclease Med9 PF07544.13 PVD36455.1 - 0.046 13.8 3.0 0.24 11.5 3.0 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 PVD36455.1 - 0.14 12.2 2.5 0.23 11.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2508 PF10704.9 PVD36455.1 - 0.7 10.1 4.1 3 8.1 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) zf-RING_6 PF14835.6 PVD36455.1 - 1.1 9.2 10.3 0.059 13.2 4.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PVD36455.1 - 2.2 8.1 22.3 0.068 13.0 7.6 3.2 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PVD36456.1 - 1.2e-08 34.8 9.2 1.2e-08 34.8 9.2 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36456.1 - 1.8e-08 34.1 11.1 1.8e-08 34.1 11.1 2.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36456.1 - 1.9e-08 34.0 7.5 1.9e-08 34.0 7.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36456.1 - 8.5e-07 29.0 8.2 8.5e-07 29.0 8.2 4.1 3 1 0 3 3 2 1 B-box zinc finger zf-RING_2 PF13639.6 PVD36456.1 - 8.8e-07 29.2 10.6 8.8e-07 29.2 10.6 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36456.1 - 1.7e-06 28.1 11.0 1.7e-06 28.1 11.0 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD36456.1 - 1.2e-05 25.1 11.2 1.2e-05 25.1 11.2 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36456.1 - 2.6e-05 24.1 10.3 2.6e-05 24.1 10.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36456.1 - 8.4e-05 22.4 9.6 8.4e-05 22.4 9.6 2.8 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD36456.1 - 5.7 6.8 24.9 0.045 13.6 7.8 3.3 2 2 2 4 4 4 0 RING/Ubox like zinc-binding domain IBR PF01485.21 PVD36456.1 - 6.1 7.2 34.5 0.48 10.7 12.2 4.6 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 PVD36457.1 - 4e-08 33.0 10.5 4e-08 33.0 10.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36457.1 - 4.5e-08 33.0 9.7 4.5e-08 33.0 9.7 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 PVD36457.1 - 1.1e-07 31.9 8.2 1.1e-07 31.9 8.2 3.7 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD36457.1 - 1.7e-07 31.0 7.5 1.7e-07 31.0 7.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36457.1 - 3.4e-06 27.1 9.7 3.4e-06 27.1 9.7 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36457.1 - 6.1e-06 26.5 11.2 6.1e-06 26.5 11.2 3.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PVD36457.1 - 2.1e-05 24.4 9.6 2.1e-05 24.4 9.6 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36457.1 - 0.00014 21.6 11.2 0.00014 21.6 11.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 PVD36457.1 - 0.0071 16.5 6.7 0.0071 16.5 6.7 3.2 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 PVD36457.1 - 0.0075 16.1 8.6 0.0075 16.1 8.6 2.9 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PVD36457.1 - 0.013 15.4 4.3 0.013 15.4 4.3 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RE_SinI PF09570.10 PVD36457.1 - 0.15 11.2 0.0 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 SinI restriction endonuclease zf-RING_4 PF14570.6 PVD36457.1 - 3.2 7.6 20.5 0.58 10.0 6.9 3.3 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain HscB_4_cys PF18256.1 PVD36457.1 - 4.7 7.1 11.6 7.2 6.5 1.5 3.9 3 1 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Eapp_C PF10238.9 PVD36457.1 - 5.9 7.0 12.6 0.054 13.6 4.6 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-B_box PF00643.24 PVD36458.1 - 4.6e-09 36.3 8.3 4.6e-09 36.3 8.3 3.4 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD36458.1 - 1.1e-08 34.8 6.6 1.1e-08 34.8 6.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36458.1 - 2.3e-08 33.8 9.3 2.3e-08 33.8 9.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36458.1 - 8.1e-07 29.0 10.3 8.1e-07 29.0 10.3 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36458.1 - 3.4e-06 26.9 8.3 3.4e-06 26.9 8.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36458.1 - 4.6e-06 26.9 9.3 4.6e-06 26.9 9.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36458.1 - 4.7e-06 26.4 10.0 4.7e-06 26.4 10.0 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36458.1 - 5.6e-05 23.2 11.0 5.6e-05 23.2 11.0 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36458.1 - 0.00093 19.0 8.0 0.00093 19.0 8.0 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Eapp_C PF10238.9 PVD36458.1 - 0.0012 19.0 1.9 0.0012 19.0 1.9 2.5 3 1 0 3 3 3 1 E2F-associated phosphoprotein zf-RING_11 PF17123.5 PVD36458.1 - 0.064 13.0 6.5 0.15 11.8 3.3 2.9 1 1 1 2 2 2 0 RING-like zinc finger IBR PF01485.21 PVD36458.1 - 0.2 11.9 18.8 0.047 13.9 9.8 3.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 PVD36458.1 - 3 7.8 11.3 0.095 12.6 4.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prot_inhib_II PF02428.15 PVD36458.1 - 4.3 7.9 10.0 0.1 13.1 2.5 2.2 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family zf-C3HC4_3 PF13920.6 PVD36459.1 - 2.2e-08 33.8 6.9 2.2e-08 33.8 6.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36459.1 - 4e-08 33.0 8.9 4e-08 33.0 8.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36459.1 - 5.2e-08 32.9 10.2 5.2e-08 32.9 10.2 3.2 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD36459.1 - 1.2e-07 31.6 7.0 1.2e-07 31.6 7.0 3.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36459.1 - 1e-06 28.5 9.2 1e-06 28.5 9.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36459.1 - 2.3e-06 27.5 8.1 2.3e-06 27.5 8.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36459.1 - 4.7e-06 26.8 9.2 4.7e-06 26.8 9.2 2.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36459.1 - 4.8e-05 23.4 10.2 4.8e-05 23.4 10.2 3.1 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36459.1 - 0.001 18.9 7.8 0.001 18.9 7.8 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36459.1 - 8.1 6.8 25.6 0.33 11.2 12.8 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 PVD36460.1 - 1.8e-08 34.1 6.5 1.8e-08 34.1 6.5 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36460.1 - 5.3e-08 32.6 8.3 5.3e-08 32.6 8.3 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36460.1 - 2.6e-07 30.7 10.1 2.6e-07 30.7 10.1 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD36460.1 - 3.6e-07 30.1 9.1 3.6e-07 30.1 9.1 2.9 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36460.1 - 6.4e-06 25.9 9.4 6.4e-06 25.9 9.4 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36460.1 - 1e-05 25.7 9.1 1e-05 25.7 9.1 3.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD36460.1 - 1.4e-05 24.9 7.6 1.4e-05 24.9 7.6 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD36460.1 - 0.0001 22.4 11.1 0.0001 22.4 11.1 3.4 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36460.1 - 0.0016 18.2 7.1 0.0016 18.2 7.1 3.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD36460.1 - 0.077 12.8 6.1 0.18 11.6 3.7 2.9 1 1 1 2 2 2 0 RING-like zinc finger Viral_alk_exo PF01771.17 PVD36461.1 - 1.3e-05 24.3 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Viral alkaline exonuclease zf-C3HC4_3 PF13920.6 PVD36462.1 - 2.8e-08 33.5 5.2 2.8e-08 33.5 5.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36462.1 - 6e-08 32.4 7.8 1.2e-07 31.5 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36462.1 - 2.5e-07 30.6 9.7 3.1e-07 30.3 8.9 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36462.1 - 3.9e-06 26.7 7.6 5.5e-06 26.2 6.9 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PVD36462.1 - 1.2e-05 25.6 10.4 1.6e-05 25.2 8.8 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 PVD36462.1 - 1.3e-05 24.9 7.0 1.3e-05 24.9 7.0 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36462.1 - 3.1e-05 23.7 8.2 3.1e-05 23.7 8.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36462.1 - 0.00011 22.2 11.2 0.00022 21.3 11.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PVD36462.1 - 0.014 15.2 4.3 0.025 14.5 4.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 PVD36462.1 - 0.038 13.9 1.2 0.038 13.9 1.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 PVD36462.1 - 1.2 9.0 10.3 2 8.2 8.7 2.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PVD36462.1 - 8.7 6.7 9.9 50 4.3 9.3 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Formyl_trans_N PF00551.19 PVD36463.1 - 0.086 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Formyl transferase zf-RING_UBOX PF13445.6 PVD36464.1 - 1.4e-09 37.8 8.7 1.4e-09 37.8 8.7 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36464.1 - 4.5e-09 36.0 7.0 4.5e-09 36.0 7.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36464.1 - 2.2e-08 34.1 8.4 2.2e-08 34.1 8.4 3.6 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36464.1 - 5.1e-08 32.7 9.9 5.1e-08 32.7 9.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36464.1 - 8.1e-07 29.1 10.0 8.1e-07 29.1 10.0 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36464.1 - 8.8e-07 29.2 10.4 8.8e-07 29.2 10.4 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36464.1 - 1.3e-05 24.9 10.9 1.3e-05 24.9 10.9 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36464.1 - 1.5e-05 24.9 9.1 1.5e-05 24.9 9.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36464.1 - 3.9e-05 23.4 8.6 3.9e-05 23.4 8.6 2.7 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36464.1 - 0.012 15.8 8.0 0.012 15.8 8.0 3.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36464.1 - 0.24 11.2 19.6 0.088 12.6 7.4 3.1 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PVD36464.1 - 6.8 6.8 10.9 1.6 8.8 2.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PVD36465.1 - 6.6e-09 35.5 6.7 6.6e-09 35.5 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36465.1 - 7.7e-09 35.4 7.1 7.7e-09 35.4 7.1 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36465.1 - 5.1e-08 32.7 7.9 5.1e-08 32.7 7.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36465.1 - 3.3e-07 30.4 9.9 3.3e-07 30.4 9.9 3.4 3 1 0 3 3 3 1 B-box zinc finger zf-RING_5 PF14634.6 PVD36465.1 - 1.4e-06 28.1 7.8 1.4e-06 28.1 7.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD36465.1 - 2.7e-06 27.4 9.2 2.7e-06 27.4 9.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36465.1 - 2.8e-06 27.6 9.2 2.8e-06 27.6 9.2 2.7 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36465.1 - 1.5e-05 24.7 8.8 1.5e-05 24.7 8.8 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36465.1 - 0.00016 21.5 7.0 0.00016 21.5 7.0 2.6 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD36465.1 - 0.031 14.1 3.2 0.031 14.1 3.2 3.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF4826 PF16108.5 PVD36465.1 - 0.13 12.5 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) IBR PF01485.21 PVD36465.1 - 1.4 9.2 23.6 0.1 12.8 9.0 3.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain HscB_4_cys PF18256.1 PVD36465.1 - 8.4 6.3 11.1 1.1 9.1 1.0 3.4 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-B_box PF00643.24 PVD36466.1 - 2.1e-09 37.4 7.3 2.1e-09 37.4 7.3 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD36466.1 - 2.9e-09 36.6 6.5 2.9e-09 36.6 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36466.1 - 4.4e-09 36.2 7.1 4.4e-09 36.2 7.1 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36466.1 - 2.8e-08 33.5 7.9 2.8e-08 33.5 7.9 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36466.1 - 7.9e-07 28.9 7.8 7.9e-07 28.9 7.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD36466.1 - 1.5e-06 28.2 9.2 1.5e-06 28.2 9.2 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36466.1 - 1.5e-06 28.4 9.2 1.5e-06 28.4 9.2 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36466.1 - 8.5e-06 25.5 8.8 8.5e-06 25.5 8.8 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36466.1 - 8.6e-05 22.3 7.0 8.6e-05 22.3 7.0 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36466.1 - 0.0037 17.5 6.4 0.0037 17.5 6.4 3.7 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36466.1 - 0.019 14.8 3.2 0.019 14.8 3.2 3.5 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain C1_4 PF07975.12 PVD36466.1 - 0.075 13.3 1.3 0.075 13.3 1.3 3.2 3 1 0 3 3 3 0 TFIIH C1-like domain HscB_4_cys PF18256.1 PVD36466.1 - 0.21 11.4 6.4 0.68 9.8 1.0 3.4 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-RING_UBOX PF13445.6 PVD36467.1 - 2.2e-09 37.2 7.9 2.2e-09 37.2 7.9 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36467.1 - 1e-08 34.9 6.5 1e-08 34.9 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36467.1 - 5.2e-08 32.6 9.4 5.2e-08 32.6 9.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36467.1 - 1.8e-07 31.2 11.2 1.8e-07 31.2 11.2 3.7 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36467.1 - 6e-07 29.5 9.4 6e-07 29.5 9.4 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36467.1 - 7.7e-07 29.3 9.5 7.7e-07 29.3 9.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PVD36467.1 - 6.4e-06 26.0 8.5 6.4e-06 26.0 8.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36467.1 - 1.4e-05 24.8 10.0 1.4e-05 24.8 10.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36467.1 - 2.2e-05 24.2 7.8 2.2e-05 24.2 7.8 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 IBR PF01485.21 PVD36467.1 - 0.0039 17.4 6.4 0.0039 17.4 6.4 3.6 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 PVD36468.1 - 1.8e-09 37.5 8.7 1.8e-09 37.5 8.7 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36468.1 - 4.3e-09 36.1 7.2 4.3e-09 36.1 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36468.1 - 6.1e-09 35.9 8.5 6.1e-09 35.9 8.5 4.3 4 1 1 5 5 5 1 B-box zinc finger zf-C3HC4 PF00097.25 PVD36468.1 - 3.3e-08 33.3 10.1 3.3e-08 33.3 10.1 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36468.1 - 8.3e-07 29.1 9.9 8.3e-07 29.1 9.9 2.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36468.1 - 1.2e-06 28.8 10.4 1.2e-06 28.8 10.4 3.0 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD36468.1 - 2.1e-06 27.6 21.6 7.2e-06 25.9 9.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36468.1 - 1.5e-05 24.7 11.0 1.5e-05 24.7 11.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36468.1 - 0.00014 21.6 8.7 0.00014 21.6 8.7 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PVD36468.1 - 0.00078 19.3 3.5 0.00078 19.3 3.5 2.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein IBR PF01485.21 PVD36468.1 - 0.0095 16.1 7.8 0.0095 16.1 7.8 3.5 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36468.1 - 3 7.7 23.0 0.071 12.9 7.4 3.4 2 2 2 4 4 4 0 RING/Ubox like zinc-binding domain C1_4 PF07975.12 PVD36468.1 - 5.6 7.3 15.3 1.4 9.2 2.1 3.1 3 0 0 3 3 3 0 TFIIH C1-like domain zf-RING_UBOX PF13445.6 PVD36469.1 - 3.2e-09 36.6 7.6 3.2e-09 36.6 7.6 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36469.1 - 1.6e-08 34.3 6.0 1.6e-08 34.3 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36469.1 - 2.5e-08 33.6 8.6 2.5e-08 33.6 8.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36469.1 - 7.4e-07 29.4 9.0 7.4e-07 29.4 9.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36469.1 - 1.8e-06 28.0 10.1 1.8e-06 28.0 10.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD36469.1 - 2.8e-06 27.4 11.9 2.8e-06 27.4 11.9 3.5 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.6 PVD36469.1 - 6.2e-06 26.1 8.0 6.2e-06 26.1 8.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36469.1 - 8e-06 25.6 9.5 8e-06 25.6 9.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36469.1 - 3.2e-05 23.7 7.1 3.2e-05 23.7 7.1 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Gp138_N PF18352.1 PVD36469.1 - 0.077 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain IBR PF01485.21 PVD36469.1 - 0.33 11.2 24.1 0.066 13.4 10.8 3.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PVD36469.1 - 1.4 8.8 18.1 0.14 11.9 6.8 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PVD36470.1 - 2.3e-08 33.7 8.8 2.3e-08 33.7 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36470.1 - 4e-08 33.1 9.1 4e-08 33.1 9.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD36470.1 - 8.7e-08 31.9 11.0 8.7e-08 31.9 11.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36470.1 - 3.4e-07 30.3 9.9 3.4e-07 30.3 9.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD36470.1 - 1.1e-06 28.9 10.6 1.1e-06 28.9 10.6 2.4 2 1 0 2 2 2 1 Ring finger domain IBR PF01485.21 PVD36470.1 - 2.2e-06 27.8 1.3 2.2e-06 27.8 1.3 2.9 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PVD36470.1 - 2.9e-06 27.0 10.1 2.9e-06 27.0 10.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36470.1 - 1.3e-05 25.2 4.9 1.3e-05 25.2 4.9 4.0 3 1 1 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.6 PVD36470.1 - 3.9e-05 23.5 10.6 3.9e-05 23.5 10.6 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD36470.1 - 0.00011 21.9 10.0 0.00011 21.9 10.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD36470.1 - 0.00097 18.9 12.6 0.0017 18.1 5.8 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-PHD-like PF15446.6 PVD36470.1 - 0.003 17.2 3.7 0.003 17.2 3.7 1.7 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-RING_6 PF14835.6 PVD36470.1 - 0.0081 16.0 2.6 0.0081 16.0 2.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zinc_ribbon_4 PF13717.6 PVD36470.1 - 0.029 14.3 7.6 1.5 8.8 0.1 4.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-ANAPC11 PF12861.7 PVD36470.1 - 0.11 12.6 5.7 0.51 10.4 2.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fzo_mitofusin PF04799.13 PVD36470.1 - 0.11 12.0 0.9 0.15 11.6 0.9 1.1 1 0 0 1 1 1 0 fzo-like conserved region Prok-RING_1 PF14446.6 PVD36470.1 - 0.73 9.8 14.6 1.5 8.8 1.6 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 CpXC PF14353.6 PVD36470.1 - 4.3 7.4 8.6 15 5.7 2.5 2.3 2 0 0 2 2 2 0 CpXC protein MIF4G PF02854.19 PVD36471.1 - 2.3e-08 33.9 5.2 3.6e-08 33.3 5.2 1.2 1 0 0 1 1 1 1 MIF4G domain SAVED PF18145.1 PVD36471.1 - 0.1 12.4 0.2 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain Ras PF00071.22 PVD36472.1 - 3e-53 179.7 0.1 3.6e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD36472.1 - 2.6e-29 101.9 0.0 3.7e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36472.1 - 2.6e-12 46.5 0.0 3.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD36472.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HIT PF01230.23 PVD36473.1 - 6.8e-30 103.7 0.1 8e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PVD36473.1 - 6.4e-21 75.0 0.0 7.7e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding G-patch PF01585.23 PVD36474.1 - 1.1e-10 41.2 0.4 1.9e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PVD36474.1 - 0.11 12.7 0.2 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 G-patch domain Glyco_hydro_59 PF02057.15 PVD36475.1 - 8.9e-107 356.7 5.5 1.3e-106 356.2 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 PVD36475.1 - 5.3e-41 139.4 0.1 9.2e-41 138.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain CBM_14 PF01607.24 PVD36475.1 - 2.1e-07 31.0 2.7 4e-07 30.1 2.7 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Glyco_hydro_30 PF02055.16 PVD36475.1 - 0.12 11.4 3.1 0.082 11.9 0.3 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain ELH PF02323.15 PVD36475.1 - 0.27 10.6 0.6 0.47 9.8 0.6 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor MKT1_C PF12246.8 PVD36479.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Sulfotransfer_1 PF00685.27 PVD36481.1 - 1.7e-35 122.8 0.3 2.1e-35 122.5 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD36481.1 - 1.3e-06 28.9 0.0 1.8e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Acyltransferase PF01553.21 PVD36481.1 - 0.057 13.0 0.0 0.29 10.7 0.0 1.9 1 1 1 2 2 2 0 Acyltransferase EGF_2 PF07974.13 PVD36482.1 - 0.044 14.2 25.4 1.1 9.7 11.2 2.9 2 0 0 2 2 2 0 EGF-like domain LAX PF15681.5 PVD36485.1 - 0.092 11.6 1.0 0.1 11.4 1.0 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X CcmD PF04995.14 PVD36485.1 - 0.19 11.8 1.3 0.25 11.5 1.1 1.4 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Zona_pellucida PF00100.23 PVD36486.1 - 0.0045 16.8 0.7 0.046 13.5 0.1 2.0 1 1 1 2 2 2 1 Zona pellucida-like domain MH1 PF03165.16 PVD36487.1 - 3.3e-19 69.0 1.2 9.7e-19 67.5 0.9 1.7 2 0 0 2 2 2 1 MH1 domain SSF PF00474.17 PVD36488.1 - 9.1e-38 130.2 18.5 1.4e-37 129.6 18.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family V-set PF07686.17 PVD36492.1 - 0.0033 17.6 0.1 0.014 15.6 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 PVD36492.1 - 0.0084 16.3 0.4 0.04 14.1 0.4 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Endomucin PF07010.12 PVD36492.1 - 0.011 15.7 0.9 0.012 15.6 0.9 1.2 1 0 0 1 1 1 0 Endomucin Ig_3 PF13927.6 PVD36492.1 - 0.025 15.2 0.3 0.072 13.7 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 PVD36492.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain SSF PF00474.17 PVD36493.1 - 9e-36 123.6 16.7 2.2e-26 92.7 12.7 2.1 2 0 0 2 2 2 2 Sodium:solute symporter family HEPN PF05168.14 PVD36493.1 - 4.5e-10 39.7 0.1 9.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 HEPN domain Gly-zipper_OmpA PF13436.6 PVD36493.1 - 0.061 13.1 0.6 0.14 12.0 0.6 1.5 1 0 0 1 1 1 0 Glycine-zipper domain LRR_8 PF13855.6 PVD36494.1 - 1.1e-45 153.3 42.3 3.5e-12 45.9 2.2 7.9 4 2 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PVD36494.1 - 5.1e-23 80.8 42.1 5.2e-05 23.5 1.5 9.0 3 3 6 11 11 11 10 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD36494.1 - 1.2e-20 74.0 0.0 3.2e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 PVD36494.1 - 3.5e-18 66.3 0.1 6.7e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD36494.1 - 2.5e-16 59.8 14.5 2.4e-07 30.8 0.5 4.0 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD36494.1 - 1.1e-05 25.0 16.0 0.16 11.4 0.1 4.6 1 1 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 PVD36494.1 - 0.0013 19.0 25.3 3.2 8.7 0.0 10.8 12 0 0 12 12 12 1 Leucine Rich Repeat DUF1863 PF08937.11 PVD36494.1 - 0.0063 16.8 0.0 0.018 15.4 0.0 1.8 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) TPKR_C2 PF16920.5 PVD36494.1 - 0.01 16.0 1.1 0.03 14.4 1.1 1.8 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain YL1 PF05764.13 PVD36495.1 - 3.9e-20 73.0 30.9 3.1e-18 66.8 18.0 3.1 2 1 1 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 PVD36495.1 - 1.9e-12 46.7 1.3 3.4e-12 45.9 0.6 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain C1q PF00386.21 PVD36497.1 - 1.9e-16 60.4 2.3 1.9e-16 60.4 2.3 2.3 4 0 0 4 4 4 1 C1q domain ig PF00047.25 PVD36497.1 - 0.0027 17.8 0.1 0.048 13.8 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 PVD36497.1 - 0.03 14.5 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain BclA_C PF18573.1 PVD36497.1 - 0.032 14.2 1.4 0.063 13.2 1.4 1.4 1 0 0 1 1 1 0 BclA C-terminal domain C6 PF01681.17 PVD36497.1 - 0.051 14.1 0.8 17 6.0 0.0 3.2 3 0 0 3 3 3 0 C6 domain Pkinase PF00069.25 PVD36498.1 - 4.6e-60 203.2 0.0 8.7e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 PVD36498.1 - 5.4e-54 180.6 26.2 1.5e-11 44.7 0.5 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat MH2 PF03166.14 PVD36498.1 - 6.7e-48 163.4 0.0 1.5e-47 162.2 0.0 1.7 1 0 0 1 1 1 1 MH2 domain Pkinase_Tyr PF07714.17 PVD36498.1 - 1.4e-39 135.9 0.0 2.8e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MH1 PF03165.16 PVD36498.1 - 4.4e-24 84.7 0.8 1.8e-23 82.7 0.8 2.2 1 0 0 1 1 1 1 MH1 domain RCC1_2 PF13540.6 PVD36498.1 - 8.4e-15 54.1 32.4 2e-06 27.4 0.1 6.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 PVD36498.1 - 1.3e-07 31.3 1.2 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PVD36498.1 - 2.2e-05 23.4 0.0 2.2e-05 23.4 0.0 2.6 2 1 1 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 PVD36498.1 - 0.005 15.8 0.0 0.014 14.3 0.0 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PVD36498.1 - 0.009 15.4 0.1 0.023 14.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 PVD36499.1 - 5.8e-63 211.3 0.1 7e-63 211.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD36499.1 - 1.9e-35 121.7 0.1 2.7e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36499.1 - 1.1e-12 47.7 0.1 1.6e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD36499.1 - 1.4e-07 31.6 0.1 2.2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PVD36499.1 - 3.4e-05 24.1 0.1 0.00037 20.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 PVD36499.1 - 4.4e-05 23.4 0.2 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD36499.1 - 9.3e-05 22.0 0.1 0.00036 20.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD36499.1 - 0.0039 16.6 0.0 0.0061 15.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PVD36499.1 - 0.011 16.1 0.1 0.017 15.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PVD36499.1 - 0.013 16.0 0.3 0.021 15.3 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 PVD36499.1 - 0.019 15.0 0.1 0.079 13.0 0.1 2.0 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 PVD36499.1 - 0.021 14.4 0.2 0.064 12.8 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 PVD36499.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PVD36499.1 - 0.023 14.2 0.0 0.055 12.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 PVD36499.1 - 0.048 13.1 0.1 0.14 11.5 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 PVD36499.1 - 0.049 13.4 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain FAD-SLDH PF12318.8 PVD36499.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_21 PF13304.6 PVD36499.1 - 0.14 11.9 0.9 0.18 11.6 0.9 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 PVD36499.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PVD36499.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ependymin PF00811.18 PVD36500.1 - 0.0059 16.9 1.1 3.4 8.0 0.0 3.3 3 0 0 3 3 3 2 Ependymin Benyvirus_P25 PF05744.11 PVD36500.1 - 0.034 13.4 0.2 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Benyvirus P25/P26 protein SRCR PF00530.18 PVD36501.1 - 1.4e-08 35.2 0.4 3e-08 34.1 0.4 1.7 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain HAP1_N PF04849.13 PVD36501.1 - 0.00049 19.4 0.3 0.00059 19.1 0.3 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 PVD36501.1 - 0.00058 20.2 1.7 0.00075 19.8 1.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 PVD36501.1 - 0.0058 17.1 8.4 0.0094 16.4 8.4 1.3 1 0 0 1 1 1 1 Cell division protein ZapB UPF0242 PF06785.11 PVD36501.1 - 0.0075 16.4 1.7 0.011 15.9 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 PVD36501.1 - 0.0096 15.5 0.5 0.014 14.9 0.5 1.1 1 0 0 1 1 1 1 Leucine zipper GIT_CC PF16559.5 PVD36501.1 - 0.011 15.6 7.6 0.021 14.7 7.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HAUS-augmin3 PF14932.6 PVD36501.1 - 0.013 15.1 0.4 0.018 14.7 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Macoilin PF09726.9 PVD36501.1 - 0.013 14.1 0.1 0.015 13.9 0.1 1.1 1 0 0 1 1 1 0 Macoilin family LRRFIP PF09738.9 PVD36501.1 - 0.016 14.7 0.7 0.023 14.2 0.7 1.2 1 0 0 1 1 1 0 LRRFIP family DUF5082 PF16888.5 PVD36501.1 - 0.019 15.2 1.4 0.034 14.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 PVD36501.1 - 0.02 15.4 2.5 0.035 14.6 2.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Invasin_D3 PF09134.10 PVD36501.1 - 0.023 15.0 3.1 2.7 8.4 0.1 2.7 3 0 0 3 3 2 0 Invasin, domain 3 DUF737 PF05300.11 PVD36501.1 - 0.031 14.6 0.5 0.053 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DHR10 PF18595.1 PVD36501.1 - 0.034 14.2 6.9 0.053 13.6 6.9 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain KASH_CCD PF14662.6 PVD36501.1 - 0.035 13.9 4.3 0.055 13.3 4.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 PVD36501.1 - 0.05 13.6 3.9 0.075 13.1 3.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 PVD36501.1 - 0.057 13.5 3.9 0.089 12.9 2.7 1.8 1 1 1 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 PVD36501.1 - 0.083 11.8 2.8 0.11 11.3 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 PVD36501.1 - 0.086 12.9 4.7 0.58 10.3 0.8 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Ig_3 PF13927.6 PVD36501.1 - 0.098 13.3 0.6 3 8.5 0.1 2.7 3 0 0 3 3 2 0 Immunoglobulin domain Jnk-SapK_ap_N PF09744.9 PVD36501.1 - 0.11 12.7 3.0 0.18 12.0 3.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 PVD36501.1 - 0.12 12.7 1.8 0.21 12.0 1.8 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HOOK PF05622.12 PVD36501.1 - 0.14 10.3 2.8 0.18 9.9 2.8 1.1 1 0 0 1 1 1 0 HOOK protein ADIP PF11559.8 PVD36501.1 - 0.14 12.2 5.1 0.22 11.6 5.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 PVD36501.1 - 0.15 12.4 2.6 0.31 11.4 2.6 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain DASH_Dam1 PF08653.10 PVD36501.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 HALZ PF02183.18 PVD36501.1 - 0.19 12.0 3.7 2.9 8.2 1.4 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 PVD36501.1 - 0.21 10.9 4.8 0.36 10.1 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 PVD36501.1 - 0.99 10.1 8.8 9.3 7.0 9.3 2.0 1 1 1 2 2 2 0 SlyX CASP_C PF08172.12 PVD36501.1 - 1.2 8.4 5.5 2 7.7 5.5 1.2 1 0 0 1 1 1 0 CASP C terminal TSC22 PF01166.18 PVD36501.1 - 1.5 9.2 6.2 7.5 6.9 0.8 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 PVD36501.1 - 2.8 7.8 8.7 4.6 7.1 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator Nnf1 PF03980.14 PVD36501.1 - 3.9 7.9 9.9 13 6.2 4.6 2.2 1 1 1 2 2 2 0 Nnf1 LURAP PF14854.6 PVD36501.1 - 7.1 6.6 5.3 0.65 10.0 0.3 1.8 3 0 0 3 3 1 0 Leucine rich adaptor protein Ependymin PF00811.18 PVD36502.1 - 2.2e-13 50.5 1.6 5.6e-10 39.6 0.1 2.4 2 0 0 2 2 2 2 Ependymin VirK PF06903.12 PVD36502.1 - 0.021 14.9 0.2 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 VirK protein TNFR_16_TM PF18422.1 PVD36503.1 - 0.014 15.3 1.0 0.027 14.4 1.0 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Formyl_trans_N PF00551.19 PVD36504.1 - 2.7e-23 82.7 0.0 1.1e-22 80.6 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PVD36504.1 - 3.3e-12 46.5 0.0 2.8e-08 33.9 0.0 2.5 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain SRCR PF00530.18 PVD36505.1 - 4.9e-39 132.9 1.3 6.6e-25 87.5 0.1 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD36505.1 - 8.2e-12 45.6 3.7 0.0034 17.9 0.3 4.7 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 PVD36505.1 - 3.8e-09 36.7 1.1 3.9e-05 23.8 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD36505.1 - 3.3e-07 30.6 6.9 0.012 16.0 0.5 4.2 3 1 0 4 4 3 2 Immunoglobulin domain APG6_N PF17675.1 PVD36505.1 - 2.4e-06 28.1 3.9 0.035 14.6 0.3 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region ZapB PF06005.12 PVD36505.1 - 2.9e-06 27.6 21.0 0.0081 16.6 6.5 2.3 2 0 0 2 2 2 2 Cell division protein ZapB HAUS-augmin3 PF14932.6 PVD36505.1 - 9.1e-06 25.4 8.4 0.012 15.3 0.9 2.1 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 3 Ependymin PF00811.18 PVD36505.1 - 2.5e-05 24.5 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ependymin Macoilin PF09726.9 PVD36505.1 - 4.5e-05 22.2 1.0 0.15 10.6 0.1 2.1 2 0 0 2 2 2 2 Macoilin family CEP63 PF17045.5 PVD36505.1 - 5.6e-05 23.2 1.2 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 Centrosomal protein of 63 kDa SRCR_2 PF15494.6 PVD36505.1 - 6.3e-05 23.4 9.0 0.17 12.4 0.0 4.3 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain SlyX PF04102.12 PVD36505.1 - 7.3e-05 23.3 13.0 0.031 14.9 2.4 2.4 2 0 0 2 2 2 2 SlyX UPF0242 PF06785.11 PVD36505.1 - 0.00023 21.3 5.6 0.19 11.8 0.4 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 PVD36505.1 - 0.00027 21.0 10.6 0.082 12.9 1.6 2.2 2 0 0 2 2 2 2 Ciliary rootlet component, centrosome cohesion Leu_zip PF15294.6 PVD36505.1 - 0.00029 20.5 4.8 0.17 11.4 0.5 2.1 2 0 0 2 2 2 2 Leucine zipper Jnk-SapK_ap_N PF09744.9 PVD36505.1 - 0.00033 20.9 9.0 0.099 12.9 1.4 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 FlxA PF14282.6 PVD36505.1 - 0.00038 20.4 9.0 0.096 12.7 0.9 2.4 2 0 0 2 2 2 2 FlxA-like protein TMF_DNA_bd PF12329.8 PVD36505.1 - 0.00077 19.4 11.4 0.11 12.6 1.8 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding RasGAP_C PF03836.15 PVD36505.1 - 0.00092 19.4 1.6 1.2 9.3 0.1 2.2 2 0 0 2 2 2 2 RasGAP C-terminus Spc7 PF08317.11 PVD36505.1 - 0.00096 18.1 8.5 0.077 11.9 1.0 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein HOOK PF05622.12 PVD36505.1 - 0.0013 17.0 3.8 0.19 9.8 0.3 2.0 2 0 0 2 2 2 2 HOOK protein CBM39 PF15886.5 PVD36505.1 - 0.0013 18.6 0.1 4 7.4 0.0 3.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 32) ADIP PF11559.8 PVD36505.1 - 0.0015 18.7 13.4 0.068 13.3 1.8 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 PVD36505.1 - 0.0022 18.2 6.7 0.35 11.0 0.4 2.2 2 0 0 2 2 2 2 Tropomyosin like ATG16 PF08614.11 PVD36505.1 - 0.0047 17.2 9.0 0.45 10.7 1.3 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 PVD36505.1 - 0.0054 16.6 13.5 0.15 11.9 2.4 2.1 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH SHE3 PF17078.5 PVD36505.1 - 0.0064 16.2 7.4 0.54 9.9 0.9 2.3 2 0 0 2 2 2 2 SWI5-dependent HO expression protein 3 CAF1-p150_N PF15557.6 PVD36505.1 - 0.0065 16.4 0.3 1.8 8.5 0.0 2.3 2 0 0 2 2 2 1 CAF1 complex subunit p150, region binding to PCNA Pullulanase_N2 PF17967.1 PVD36505.1 - 0.0094 16.8 0.5 11 6.9 0.1 3.1 2 0 0 2 2 2 0 Pullulanase N2 domain YabA PF06156.13 PVD36505.1 - 0.012 16.3 7.1 1 10.0 0.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA LRRFIP PF09738.9 PVD36505.1 - 0.014 14.9 6.4 0.93 8.9 0.7 2.1 2 0 0 2 2 2 0 LRRFIP family GAS PF13851.6 PVD36505.1 - 0.015 14.7 10.2 0.45 9.8 1.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 PVD36505.1 - 0.02 15.2 5.6 1.7 8.9 0.4 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DHR10 PF18595.1 PVD36505.1 - 0.024 14.7 12.5 0.58 10.2 2.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Myosin_tail_1 PF01576.19 PVD36505.1 - 0.024 12.4 3.5 1.4 6.6 0.3 2.0 2 0 0 2 2 2 0 Myosin tail HALZ PF02183.18 PVD36505.1 - 0.026 14.7 14.5 1.1 9.5 0.6 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper CASP_C PF08172.12 PVD36505.1 - 0.032 13.6 9.2 0.65 9.3 1.1 2.2 2 0 0 2 2 2 0 CASP C terminal APG17 PF04108.12 PVD36505.1 - 0.033 13.3 6.1 1.3 8.0 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF3450 PF11932.8 PVD36505.1 - 0.034 13.5 9.4 0.76 9.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.25 PVD36505.1 - 0.035 13.8 3.2 3.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Syntaxin CENP-F_leu_zip PF10473.9 PVD36505.1 - 0.036 14.1 10.0 0.98 9.4 1.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.6 PVD36505.1 - 0.037 13.2 9.0 0.71 8.9 1.0 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Big_6 PF17936.1 PVD36505.1 - 0.043 14.1 0.1 76 3.7 0.1 3.9 3 0 0 3 3 3 0 Bacterial Ig domain bZIP_1 PF00170.21 PVD36505.1 - 0.071 13.2 17.4 1.1 9.4 0.4 4.1 2 2 2 4 4 4 0 bZIP transcription factor DUF737 PF05300.11 PVD36505.1 - 0.072 13.4 1.7 12 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) CENP-H PF05837.12 PVD36505.1 - 0.08 13.3 9.7 1.7 9.1 1.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NEMP PF10225.9 PVD36505.1 - 0.081 12.6 0.5 5.6 6.5 0.1 2.2 2 0 0 2 2 2 0 NEMP family SKA2 PF16740.5 PVD36505.1 - 0.092 12.5 8.6 1.4 8.7 0.9 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1918 PF08940.11 PVD36505.1 - 0.1 12.2 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Striatin PF08232.12 PVD36505.1 - 0.1 13.2 3.7 7.1 7.2 0.3 2.2 2 0 0 2 2 2 0 Striatin family DUF3552 PF12072.8 PVD36505.1 - 0.12 11.8 7.0 2.1 7.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HAP1_N PF04849.13 PVD36505.1 - 0.12 11.5 7.5 2 7.5 0.8 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF4140 PF13600.6 PVD36505.1 - 0.14 12.6 2.3 16 6.0 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4618 PF15397.6 PVD36505.1 - 0.17 11.3 8.5 1.4 8.2 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Ax_dynein_light PF10211.9 PVD36505.1 - 0.17 11.8 5.6 4.5 7.2 0.5 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Uso1_p115_C PF04871.13 PVD36505.1 - 0.27 11.6 7.9 4.5 7.7 1.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Taxilin PF09728.9 PVD36505.1 - 0.27 10.4 10.5 1.8 7.7 1.6 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein KLRAQ PF10205.9 PVD36505.1 - 0.34 11.2 8.8 3.2 8.1 0.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein JAKMIP_CC3 PF16034.5 PVD36505.1 - 0.39 10.6 6.2 6 6.8 0.6 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain JIP_LZII PF16471.5 PVD36505.1 - 0.4 10.9 7.3 5.6 7.2 0.8 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SpecificRecomb PF10136.9 PVD36505.1 - 0.42 8.8 4.1 0.71 8.1 0.2 2.0 2 0 0 2 2 2 0 Site-specific recombinase DUF4525 PF15027.6 PVD36505.1 - 0.44 10.3 4.6 10 5.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Med9 PF07544.13 PVD36505.1 - 0.49 10.5 7.1 7.1 6.8 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Myc-LZ PF02344.15 PVD36505.1 - 0.55 10.4 10.3 4.6 7.4 1.7 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain DASH_Dad3 PF08656.10 PVD36505.1 - 0.58 10.3 6.7 7.7 6.7 0.6 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4510 PF14971.6 PVD36505.1 - 0.6 10.4 4.2 15 5.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) FliD_C PF07195.12 PVD36505.1 - 0.61 9.5 4.7 10 5.5 0.4 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus THOC7 PF05615.13 PVD36505.1 - 1.1 9.6 9.1 7.5 6.8 1.3 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Nup54 PF13874.6 PVD36505.1 - 1.1 9.4 10.1 4.4 7.4 1.3 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 E2F_CC-MB PF16421.5 PVD36505.1 - 1.3 9.4 7.6 9.6 6.6 0.6 2.7 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF5103 PF17116.5 PVD36505.1 - 1.4 8.1 5.3 13 4.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5103) FlaC_arch PF05377.11 PVD36505.1 - 1.4 9.3 8.9 9.9 6.6 0.6 3.1 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 PVD36505.1 - 1.5 8.7 9.8 6.9 6.5 1.4 2.2 2 0 0 2 2 2 0 Sec34-like family Fmp27_WPPW PF10359.9 PVD36505.1 - 1.8 7.4 5.9 7.6 5.3 0.5 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain MAD PF05557.13 PVD36505.1 - 1.9 6.7 9.6 4 5.7 1.4 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Rac1 PF09632.10 PVD36505.1 - 1.9 7.6 6.6 7.7 5.6 0.6 2.2 2 0 0 2 2 2 0 Rac1-binding domain KfrA_N PF11740.8 PVD36505.1 - 2 9.1 8.6 12 6.6 1.2 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term GIT_CC PF16559.5 PVD36505.1 - 2 8.3 19.3 5.7 6.9 5.7 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nsp1_C PF05064.13 PVD36505.1 - 2 8.2 8.1 11 5.9 1.1 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region GrpE PF01025.19 PVD36505.1 - 2.1 8.0 5.3 16 5.1 0.3 2.3 2 0 0 2 2 2 0 GrpE BLOC1_2 PF10046.9 PVD36505.1 - 2.1 8.7 6.7 16 5.9 0.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 PVD36505.1 - 2.1 8.7 15.3 5.3 7.5 3.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 PVD36505.1 - 2.2 7.4 4.9 17 4.6 0.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein FPP PF05911.11 PVD36505.1 - 2.6 6.1 6.3 8 4.5 0.6 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil GCN5L1 PF06320.13 PVD36505.1 - 3.7 7.7 6.7 20 5.4 0.6 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Fungal_TACC PF12709.7 PVD36505.1 - 3.9 8.0 6.4 27 5.3 0.5 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins COG6 PF06419.11 PVD36505.1 - 5 5.2 8.7 5.2 5.2 1.2 2.0 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Prefoldin_2 PF01920.20 PVD36505.1 - 6.6 6.7 9.3 14 5.7 1.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit RmuC PF02646.16 PVD36505.1 - 10 5.2 10.3 7.9 5.5 1.4 2.1 2 0 0 2 2 2 0 RmuC family Sushi PF00084.20 PVD36506.1 - 1.4e-07 32.0 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) HRM PF02793.22 PVD36506.1 - 0.00025 21.3 1.1 0.0031 17.8 0.1 2.5 3 0 0 3 3 3 1 Hormone receptor domain TMEM154 PF15102.6 PVD36506.1 - 0.0019 18.1 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PVD36506.1 - 0.019 15.8 0.0 0.029 15.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sh_2 PF17512.2 PVD36506.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein Protocadherin PF08374.11 PVD36506.1 - 0.083 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Myosin_head PF00063.21 PVD36507.1 - 3.5e-250 831.9 26.6 5.2e-244 811.5 9.7 3.0 2 1 1 3 3 3 2 Myosin head (motor domain) DIL PF01843.19 PVD36507.1 - 3.4e-30 104.4 2.6 1.5e-29 102.4 2.6 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 PVD36507.1 - 2.3e-17 61.1 50.6 0.0008 19.0 1.8 7.6 7 0 0 7 7 7 6 IQ calmodulin-binding motif AAA_22 PF13401.6 PVD36507.1 - 0.018 15.3 0.2 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 PVD36507.1 - 0.029 14.2 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 PVD36507.1 - 0.039 14.3 0.0 0.38 11.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain RRM_1 PF00076.22 PVD36508.1 - 1e-18 66.9 0.0 1.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PVD36509.1 - 2.6e-24 84.8 0.0 2.3e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PVD36509.1 - 0.0035 17.3 0.0 0.7 10.0 0.0 3.3 3 1 0 3 3 3 1 RNA binding domain RRM_5 PF13893.6 PVD36509.1 - 0.0078 15.8 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD36509.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 PVD36510.1 - 0.00034 20.4 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD36510.1 - 0.018 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif VioE PF18234.1 PVD36511.1 - 0.004 17.3 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 Violacein biosynthetic enzyme VioE BRICHOS PF04089.14 PVD36511.1 - 0.0093 16.2 0.3 0.073 13.3 0.0 2.5 3 0 0 3 3 3 1 BRICHOS domain EF-hand_7 PF13499.6 PVD36513.1 - 1.4e-05 25.5 0.3 1.8e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD36513.1 - 0.00098 18.9 1.3 0.029 14.3 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD36513.1 - 0.011 15.3 0.3 0.17 11.5 0.1 2.1 1 1 1 2 2 2 0 EF hand E1_FCCH PF16190.5 PVD36513.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Carn_acyltransf PF00755.20 PVD36514.1 - 5.9e-184 613.0 0.2 6.7e-184 612.8 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Collagen PF01391.18 PVD36515.1 - 1.3e-19 69.6 78.1 2.1e-08 33.8 24.8 3.8 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) THAP PF05485.12 PVD36515.1 - 7.9e-13 49.2 0.9 7.9e-13 49.2 0.9 3.3 3 0 0 3 3 3 1 THAP domain Ig_3 PF13927.6 PVD36515.1 - 3.2e-08 34.1 0.3 2.5e-07 31.2 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 PVD36515.1 - 6.1e-08 32.6 0.5 0.006 16.6 0.0 3.3 2 1 1 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36515.1 - 3.8e-05 23.9 2.2 8.5e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 PVD36515.1 - 0.00025 21.2 0.4 0.1 12.8 0.1 3.2 2 1 0 2 2 2 1 Immunoglobulin domain zf-C2H2_4 PF13894.6 PVD36515.1 - 0.015 16.1 4.6 0.015 16.1 4.6 8.2 8 1 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD36515.1 - 6.9 6.5 8.9 1.2 8.9 1.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2722 PF10846.8 PVD36516.1 - 1.5 7.6 4.3 8.9 5.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) adh_short PF00106.25 PVD36517.1 - 5e-30 104.4 0.5 4.2e-28 98.1 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD36517.1 - 1.4e-21 77.2 0.6 9.7e-19 67.8 0.6 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 PVD36517.1 - 0.00045 19.7 0.0 0.00096 18.6 0.0 1.4 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 PVD36517.1 - 0.0035 17.3 1.7 0.012 15.5 0.2 2.3 2 1 1 3 3 3 1 KR domain 3Beta_HSD PF01073.19 PVD36517.1 - 0.018 14.1 0.2 0.031 13.3 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SAC3_GANP PF03399.16 PVD36518.1 - 2.3e-82 276.7 0.1 2.8e-82 276.4 0.1 1.0 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PVD36518.1 - 0.00013 22.0 0.1 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GNT-I PF03071.15 PVD36520.1 - 2e-110 369.5 0.8 4.7e-68 229.9 0.3 2.1 2 0 0 2 2 2 2 GNT-I family Glyco_tranf_2_3 PF13641.6 PVD36520.1 - 0.0098 15.8 0.1 0.94 9.3 0.0 3.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 PBP_sp32 PF07222.12 PVD36520.1 - 0.014 14.9 0.6 0.023 14.1 0.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MGAT2 PF05060.14 PVD36520.1 - 0.017 14.2 0.9 0.65 9.0 0.2 2.2 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) CRAL_TRIO_2 PF13716.6 PVD36521.1 - 7.6e-32 110.3 0.7 1.7e-31 109.2 0.7 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BNIP2 PF12496.8 PVD36521.1 - 1.9e-23 83.4 1.1 1.9e-23 83.4 1.1 5.8 5 2 0 5 5 5 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DHHA2 PF02833.14 PVD36521.1 - 2.6e-23 82.8 0.0 5.8e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 PVD36521.1 - 2.3e-07 31.0 0.1 5e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 DHH family CRAL_TRIO PF00650.20 PVD36521.1 - 5.3e-05 23.0 0.2 9.9e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Na_K-ATPase PF00287.18 PVD36522.1 - 4.3e-38 131.1 0.1 2.2e-37 128.8 0.1 1.8 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain Thymidylat_synt PF00303.19 PVD36522.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase p450 PF00067.22 PVD36523.1 - 8e-72 242.5 0.0 9.3e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EST1 PF10374.9 PVD36523.1 - 0.015 15.9 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Telomerase activating protein Est1 TNFR_16_TM PF18422.1 PVD36523.1 - 0.69 9.9 2.7 1.4 8.9 2.7 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain p450 PF00067.22 PVD36524.1 - 1.7e-78 264.4 0.0 2.4e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MRF_C1 PF13887.6 PVD36524.1 - 0.0092 15.1 1.3 0.053 12.7 0.1 2.6 3 0 0 3 3 3 1 Myelin gene regulatory factor -C-terminal domain 1 Cyclophil_like PF04126.13 PVD36524.1 - 0.045 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Cyclophilin-like p450 PF00067.22 PVD36525.1 - 3.1e-147 491.1 0.0 6.4e-74 249.4 0.0 3.3 2 2 1 3 3 3 3 Cytochrome P450 Salt_tol_Pase PF09506.10 PVD36525.1 - 0.044 12.6 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) p450 PF00067.22 PVD36526.1 - 2.5e-133 445.2 0.0 2.2e-65 221.2 0.0 3.0 2 2 0 2 2 2 2 Cytochrome P450 MRF_C1 PF13887.6 PVD36526.1 - 0.26 10.5 1.3 0.44 9.7 0.3 1.9 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 p450 PF00067.22 PVD36527.1 - 1.4e-74 251.5 0.0 1.8e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MRF_C1 PF13887.6 PVD36527.1 - 0.006 15.7 0.4 0.016 14.4 0.4 1.6 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 HSP70 PF00012.20 PVD36527.1 - 0.059 11.6 0.0 0.094 10.9 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein p450 PF00067.22 PVD36528.1 - 9.5e-62 209.2 0.2 5.2e-54 183.7 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD36529.1 - 4.4e-149 497.2 0.0 1e-75 255.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MRF_C1 PF13887.6 PVD36529.1 - 0.044 13.0 0.2 0.83 8.9 0.3 2.7 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 p450 PF00067.22 PVD36530.1 - 4.7e-74 249.8 0.0 5.8e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MRF_C1 PF13887.6 PVD36530.1 - 0.014 14.5 0.5 0.033 13.4 0.5 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 p450 PF00067.22 PVD36531.1 - 5.7e-33 114.3 0.1 4e-30 105.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF758 PF05527.11 PVD36531.1 - 0.16 11.9 0.5 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF758) p450 PF00067.22 PVD36532.1 - 3.1e-47 161.4 0.0 7.6e-46 156.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MRF_C1 PF13887.6 PVD36532.1 - 8.3 5.7 7.2 0.17 11.1 0.3 1.8 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 AIG1 PF04548.16 PVD36533.1 - 1.1e-29 103.3 0.0 1.9e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Sigma70_r3 PF04539.16 PVD36533.1 - 0.041 14.0 0.9 0.16 12.1 0.9 2.0 1 1 0 1 1 1 0 Sigma-70 region 3 EIF_2_alpha PF07541.12 PVD36533.1 - 0.092 12.8 0.3 0.22 11.6 0.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Neur_chan_LBD PF02931.23 PVD36534.1 - 4e-38 131.0 0.0 6.1e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD36534.1 - 1.7e-19 70.8 0.0 3.7e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AAA_30 PF13604.6 PVD36534.1 - 0.00034 20.4 0.0 0.0013 18.5 0.0 1.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PVD36534.1 - 0.0065 16.8 0.0 0.035 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD36534.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Sec23_trunk PF04811.15 PVD36534.1 - 0.012 15.2 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain AAA_22 PF13401.6 PVD36534.1 - 0.03 14.6 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 PVD36534.1 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PVD36534.1 - 0.055 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PVD36534.1 - 0.081 12.9 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PVD36534.1 - 0.097 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 PVD36534.1 - 0.22 10.9 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein zf-A20 PF01754.16 PVD36535.1 - 2e-10 40.4 6.6 2e-10 40.4 6.6 2.2 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 PVD36535.1 - 1.4e-09 37.9 9.7 1.4e-09 37.9 9.7 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger RecO_C PF02565.15 PVD36535.1 - 0.096 12.5 0.8 0.19 11.5 0.8 1.4 1 0 0 1 1 1 0 Recombination protein O C terminal zf-H2C2_2 PF13465.6 PVD36536.1 - 5.3e-65 213.1 91.0 1.3e-08 34.8 0.3 14.3 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 PVD36536.1 - 1.1e-58 192.5 89.5 1.1e-05 25.6 0.3 13.5 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36536.1 - 1.5e-37 125.0 95.9 0.00047 20.8 0.4 13.8 14 0 0 14 14 13 12 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD36536.1 - 1.3e-18 66.4 65.9 0.00045 19.9 2.5 12.1 12 0 0 12 12 12 8 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD36536.1 - 1.5e-11 43.9 102.3 0.014 15.4 0.4 13.7 13 1 0 13 13 13 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD36536.1 - 4.8e-05 23.6 48.3 0.04 14.2 5.6 6.1 1 1 7 8 8 8 4 C2H2-type zinc ribbon zf-met PF12874.7 PVD36536.1 - 0.00014 22.1 68.5 0.035 14.5 0.4 11.4 12 0 0 12 12 11 5 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 PVD36536.1 - 0.0011 19.6 52.4 0.22 12.3 1.1 7.4 3 2 6 9 9 9 3 zinc-ribbon family zf-C2H2_jaz PF12171.8 PVD36536.1 - 0.0053 17.0 53.9 1.4 9.3 0.1 11.4 13 0 0 13 13 12 3 Zinc-finger double-stranded RNA-binding Yippee-Mis18 PF03226.14 PVD36536.1 - 0.017 15.3 5.3 0.017 15.3 5.3 6.2 5 2 0 5 5 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_3rep PF18868.1 PVD36536.1 - 0.02 15.6 6.5 0.02 15.6 6.5 8.0 3 1 2 6 6 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 PVD36536.1 - 0.031 14.7 72.0 0.079 13.4 0.7 12.4 2 2 8 10 10 10 0 C2HE / C2H2 / C2HC zinc-binding finger IBD PF10416.9 PVD36536.1 - 0.035 14.1 1.1 26 4.8 0.0 4.4 3 1 0 4 4 4 0 Transcription-initiator DNA-binding domain IBD DUF3268 PF11672.8 PVD36536.1 - 0.088 13.1 0.1 0.088 13.1 0.1 6.7 4 2 2 7 7 7 0 zinc-finger-containing domain ADK_lid PF05191.14 PVD36536.1 - 0.12 12.3 32.9 0.89 9.6 1.3 7.9 6 2 0 6 6 6 0 Adenylate kinase, active site lid BolA PF01722.18 PVD36536.1 - 0.14 12.5 15.5 2.6 8.4 1.5 5.1 3 1 0 4 4 4 0 BolA-like protein zf-H2C2_5 PF13909.6 PVD36536.1 - 0.2 11.4 0.1 0.2 11.4 0.1 12.2 13 2 0 13 13 11 0 C2H2-type zinc-finger domain JIP_LZII PF16471.5 PVD36536.1 - 0.55 10.4 11.9 0.73 10.0 0.6 2.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II C1_4 PF07975.12 PVD36536.1 - 0.66 10.3 55.6 0.19 12.0 1.8 8.2 3 2 6 9 9 9 0 TFIIH C1-like domain GAGA PF09237.11 PVD36536.1 - 1.8 8.4 31.9 0.14 12.0 1.5 7.1 4 2 3 8 8 8 0 GAGA factor Zn-ribbon_8 PF09723.10 PVD36536.1 - 2.1 8.6 60.9 1 9.5 0.4 9.4 4 2 7 11 11 11 0 Zinc ribbon domain UPF0242 PF06785.11 PVD36536.1 - 3.8 7.6 27.2 0.12 12.5 17.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus zf_UBZ PF18439.1 PVD36536.1 - 5.5 6.7 41.9 6.4 6.5 0.1 11.2 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger Aconitase PF00330.20 PVD36538.1 - 2.2e-180 600.6 0.0 2.8e-180 600.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PVD36538.1 - 2.1e-41 141.3 0.0 1.7e-40 138.4 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain Ribosomal_L7Ae PF01248.26 PVD36539.1 - 9.2e-18 63.8 0.3 1.8e-17 62.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HLH PF00010.26 PVD36540.1 - 3.4e-12 46.1 0.6 9.5e-12 44.7 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nha1_C PF08619.10 PVD36540.1 - 0.0043 16.3 11.6 0.0076 15.5 11.6 1.3 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DNA_ligase_A_N PF04675.14 PVD36540.1 - 0.24 11.7 0.6 0.42 10.9 0.6 1.3 1 0 0 1 1 1 0 DNA ligase N terminus Cwf_Cwc_15 PF04889.12 PVD36540.1 - 0.28 10.9 11.1 0.46 10.2 11.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.7 PVD36540.1 - 1.3 7.0 9.1 2 6.4 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SYCE1 PF15233.6 PVD36540.1 - 2.1 8.4 10.0 1.5 8.9 0.5 2.4 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 CDC45 PF02724.14 PVD36540.1 - 4.8 5.4 10.4 7 4.8 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MYCBPAP PF14646.6 PVD36543.1 - 2.4e-126 422.2 0.0 3.8e-126 421.6 0.0 1.3 1 0 0 1 1 1 1 MYCBP-associated protein family LRR_6 PF13516.6 PVD36544.1 - 1.2e-16 59.3 47.9 0.0027 17.6 0.0 13.3 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 PVD36544.1 - 5.4e-08 33.0 32.9 0.084 13.3 0.2 9.4 8 1 1 9 9 9 5 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 PVD36544.1 - 0.00053 19.8 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 PVD36544.1 - 0.72 9.7 27.9 1.1 9.1 0.3 9.1 8 2 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.33 PVD36544.1 - 7 7.6 26.5 4.6 8.2 0.2 9.4 10 2 0 10 10 10 0 Leucine Rich Repeat ERAP1_C PF11838.8 PVD36545.1 - 2.4e-237 786.2 22.1 1e-71 242.1 3.2 6.5 5 1 0 5 5 5 5 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD36545.1 - 1.4e-208 688.4 35.7 1.1e-64 218.1 0.3 5.5 4 1 1 5 5 5 5 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD36545.1 - 1.3e-141 468.8 3.6 1.3e-38 133.1 0.0 5.8 4 1 1 5 5 5 5 Peptidase M1 N-terminal domain DUF45 PF01863.17 PVD36545.1 - 0.00015 21.9 2.5 0.51 10.3 0.1 3.8 4 0 0 4 4 4 1 Protein of unknown function DUF45 DUF3224 PF11528.8 PVD36545.1 - 0.0071 16.1 2.7 12 5.7 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3224) Peptidase_M78 PF06114.13 PVD36545.1 - 0.02 14.8 0.0 40 4.2 0.0 3.5 3 0 0 3 3 3 0 IrrE N-terminal-like domain DUF237 PF03072.14 PVD36545.1 - 0.07 13.2 1.8 26 4.8 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF237) Peptidase_M48 PF01435.18 PVD36545.1 - 0.13 12.1 0.0 68 3.2 0.0 3.3 3 0 0 3 3 3 0 Peptidase family M48 7tm_1 PF00001.21 PVD36546.1 - 9.5e-29 100.5 1.5 1.5e-28 99.9 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LapA_dom PF06305.11 PVD36546.1 - 0.015 15.1 0.6 2.9 7.8 0.1 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AGTRAP PF06396.11 PVD36546.1 - 0.31 10.8 5.2 0.81 9.5 1.3 2.5 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF1772 PF08592.11 PVD36546.1 - 0.61 10.4 7.6 13 6.0 4.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.21 PVD36547.1 - 6.1e-16 58.5 2.5 7.4e-16 58.2 2.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 PVD36547.1 - 7.4 6.9 9.3 4.1 7.7 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) FIST PF08495.10 PVD36548.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 FIST N domain 7tm_1 PF00001.21 PVD36549.1 - 6.1e-23 81.5 5.0 7.1e-23 81.3 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD36549.1 - 0.00039 19.9 10.1 0.00058 19.3 10.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx XK-related PF09815.9 PVD36549.1 - 0.016 14.3 17.2 0.071 12.2 11.7 2.3 2 0 0 2 2 2 0 XK-related protein LapA_dom PF06305.11 PVD36549.1 - 0.058 13.2 0.3 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FixQ PF05545.11 PVD36549.1 - 0.53 10.3 9.4 0.4 10.7 0.2 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ 7tm_1 PF00001.21 PVD36550.1 - 2.1e-08 33.9 4.3 2.9e-08 33.4 4.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD36550.1 - 1.9e-05 24.1 1.8 2.6e-05 23.7 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD36550.1 - 3.9e-05 23.1 3.1 5.3e-05 22.7 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD36550.1 - 0.04 13.5 5.4 0.06 13.0 5.5 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx HtrL_YibB PF09612.10 PVD36551.1 - 2.3e-19 69.9 1.0 1.4e-12 47.8 0.1 2.8 2 1 0 2 2 2 2 Bacterial protein of unknown function (HtrL_YibB) DUF1201 PF06716.11 PVD36551.1 - 0.012 15.6 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Herpes_HEPA PF03324.14 PVD36551.1 - 0.023 15.1 0.3 4.4 7.8 0.0 3.0 3 1 0 3 3 3 0 Herpesvirus DNA helicase/primase complex associated protein HtrL_YibB PF09612.10 PVD36552.1 - 4e-09 36.4 0.0 4.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) HtrL_YibB PF09612.10 PVD36553.1 - 0.00043 19.9 0.0 0.69 9.4 0.0 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (HtrL_YibB) zf-RING_2 PF13639.6 PVD36554.1 - 4.6e-08 33.3 2.5 4.6e-08 33.3 2.5 3.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 PVD36554.1 - 2.4e-07 30.3 5.0 2.4e-07 30.3 5.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PVD36554.1 - 2.2e-06 27.9 0.5 1.7e-05 25.0 0.5 2.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 PVD36554.1 - 0.00024 20.7 0.1 0.00024 20.7 0.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 PVD36554.1 - 0.00026 20.8 1.8 0.00026 20.8 1.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36554.1 - 0.00039 20.4 1.6 0.0018 18.3 1.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36554.1 - 0.00041 20.1 2.2 0.0014 18.4 2.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PVD36554.1 - 0.0016 18.4 0.2 0.0067 16.4 0.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PVD36554.1 - 0.19 11.9 6.1 0.061 13.5 0.6 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain DZF PF07528.14 PVD36555.1 - 4.5e-93 311.4 0.2 5.8e-93 311.1 0.2 1.1 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 PVD36555.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Peptidase_M1 PF01433.20 PVD36556.1 - 1.1e-73 247.5 4.3 1.1e-73 247.4 3.0 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 PVD36556.1 - 1e-49 169.8 0.9 8.6e-49 166.8 0.9 2.1 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PVD36556.1 - 9.3e-43 146.6 0.0 1.5e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Glyco_transf_7N PF13733.6 PVD36557.1 - 1.7e-42 144.3 0.0 2.6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PVD36557.1 - 3.6e-26 90.6 0.2 7.6e-26 89.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase MacB_PCD PF12704.7 PVD36557.1 - 0.041 14.2 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain B12D PF06522.11 PVD36559.1 - 1.6e-16 59.9 0.1 1.9e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit KH_1 PF00013.29 PVD36560.1 - 1.8e-05 24.5 0.6 2.8e-05 23.8 0.6 1.3 1 0 0 1 1 1 1 KH domain Ras PF00071.22 PVD36561.1 - 3.4e-52 176.3 0.2 3.9e-52 176.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD36561.1 - 2.2e-26 92.4 0.1 3.3e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36561.1 - 4.2e-13 49.1 0.1 4.8e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD36561.1 - 5.2e-06 26.5 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PVD36561.1 - 8.3e-06 25.3 0.0 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 PVD36561.1 - 1e-05 25.2 0.0 5.2e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD36561.1 - 0.0003 20.4 0.1 0.015 14.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD36561.1 - 0.00042 19.7 0.4 0.00072 19.0 0.4 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 PVD36561.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF3963 PF13124.6 PVD36561.1 - 0.2 11.7 0.4 0.4 10.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) MFS_1 PF07690.16 PVD36562.1 - 7e-33 114.0 31.6 2.4e-32 112.2 16.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36562.1 - 6.9e-32 110.9 6.9 6.9e-32 110.9 6.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 PVD36562.1 - 6.2e-09 35.6 8.1 6.2e-09 35.6 8.1 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 PVD36562.1 - 7.7e-09 34.4 6.1 7.3e-05 21.2 0.3 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Ras PF00071.22 PVD36563.1 - 5.2e-67 224.5 0.4 6.2e-67 224.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD36563.1 - 1.1e-35 122.4 0.2 2.1e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36563.1 - 7e-17 61.4 0.3 9.1e-17 61.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD36563.1 - 7.5e-07 28.7 0.2 9.8e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD36563.1 - 1.5e-05 24.5 0.1 1.9e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD36563.1 - 0.00019 21.0 0.1 0.00053 19.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD36563.1 - 0.00023 21.2 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD36563.1 - 0.002 18.1 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 PVD36563.1 - 0.017 14.4 0.3 0.067 12.5 0.0 2.0 2 1 1 3 3 3 0 Septin DUF3963 PF13124.6 PVD36563.1 - 0.028 14.4 0.8 0.055 13.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_16 PF13191.6 PVD36563.1 - 0.08 13.3 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 PVD36563.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 PVD36563.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PVD36563.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 PVD36564.1 - 8.6e-29 100.2 0.0 1.1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Ribosomal_S27e PF01667.17 PVD36564.1 - 1.9e-27 94.7 1.8 3.2e-27 94.0 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Roc PF08477.13 PVD36564.1 - 5.3e-11 42.8 0.0 8.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD36564.1 - 4e-05 23.1 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Hormone_6 PF00236.18 PVD36564.1 - 0.038 14.0 0.2 2.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Glycoprotein hormone SRPRB PF09439.10 PVD36564.1 - 0.07 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PVD36564.1 - 0.08 12.5 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain fn3 PF00041.21 PVD36565.1 - 2.8e-83 274.3 20.6 6.3e-16 58.5 0.1 6.6 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 PVD36565.1 - 2.9e-40 136.2 0.0 5.5e-16 58.4 0.0 6.0 5 0 0 5 5 5 3 Immunoglobulin I-set domain Neogenin_C PF06583.12 PVD36565.1 - 1.7e-36 126.6 4.7 5.3e-36 124.9 4.7 1.9 1 1 0 1 1 1 1 Neogenin C-terminus Ig_3 PF13927.6 PVD36565.1 - 2.8e-33 114.4 0.1 9.8e-13 48.5 0.0 5.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD36565.1 - 5.4e-18 65.1 0.0 8e-05 22.9 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD36565.1 - 2.6e-17 63.2 19.3 0.0043 17.6 0.0 7.4 6 1 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD36565.1 - 4.9e-14 52.5 0.2 0.021 15.1 0.0 6.6 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.25 PVD36565.1 - 9e-13 48.2 0.1 0.00011 22.3 0.0 5.2 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 PVD36565.1 - 7e-12 45.5 2.7 0.23 11.6 0.0 7.8 8 1 1 9 9 9 3 Immunoglobulin V-set domain DUF2369 PF10179.9 PVD36565.1 - 1e-09 38.6 5.0 0.016 15.6 0.1 6.2 6 0 0 6 6 6 2 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 PVD36565.1 - 0.00042 20.3 0.1 1.8 8.7 0.0 4.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Mid2 PF04478.12 PVD36565.1 - 0.028 14.2 0.3 0.067 13.0 0.3 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Arylsulfotran_N PF17425.2 PVD36565.1 - 1.8 8.7 4.7 32 4.6 0.1 3.7 4 0 0 4 4 4 0 Arylsulfotransferase Ig-like domain CARDB PF07705.11 PVD36565.1 - 2.2 8.6 6.6 30 4.9 0.1 4.5 4 0 0 4 4 4 0 CARDB Lectin_leg-like PF03388.13 PVD36566.1 - 5.5e-82 274.6 0.0 7.5e-82 274.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 PVD36566.1 - 3.4e-14 53.3 0.0 6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin Sec34 PF04136.15 PVD36566.1 - 0.066 13.1 0.6 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 Sec34-like family UvrD_C PF13361.6 PVD36566.1 - 0.07 12.5 0.4 0.24 10.7 0.4 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain TAFH PF07531.14 PVD36570.1 - 0.013 15.6 0.6 0.028 14.5 0.0 1.8 2 0 0 2 2 2 0 NHR1 homology to TAF SIX1_SD PF16878.5 PVD36570.1 - 0.032 14.7 0.5 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain Peptidase_M15 PF01427.17 PVD36570.1 - 0.049 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase ZU5 PF00791.20 PVD36571.1 - 3.8e-07 30.3 0.0 9.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Gti1_Pac2 PF09729.9 PVD36571.1 - 0.17 11.9 1.7 0.27 11.3 1.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4371 PF14291.6 PVD36572.1 - 0.0045 16.7 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) ZU5 PF00791.20 PVD36573.1 - 2.1e-09 37.6 0.1 6e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 ZU5 domain ZU5 PF00791.20 PVD36575.1 - 6.4e-10 39.3 0.1 1.5e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 ZU5 domain CRAL_TRIO_2 PF13716.6 PVD36575.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ZU5 PF00791.20 PVD36576.1 - 1.4e-08 34.9 0.3 6.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 ZU5 domain ZU5 PF00791.20 PVD36577.1 - 1.7e-11 44.3 0.0 4.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain TMEMspv1-c74-12 PF11044.8 PVD36577.1 - 0.07 13.1 1.4 4.4 7.4 2.4 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CALM_bind PF16025.5 PVD36578.1 - 0.57 10.7 6.7 0.098 13.1 1.9 2.0 1 1 1 2 2 2 0 Calcium-dependent calmodulin binding CSD PF00313.22 PVD36579.1 - 7.6e-12 44.9 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain ZU5 PF00791.20 PVD36580.1 - 6.6e-09 36.0 0.0 2.6e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 ZU5 domain ZU5 PF00791.20 PVD36581.1 - 1.8e-10 41.0 0.1 6e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 ZU5 domain ZU5 PF00791.20 PVD36583.1 - 3.5e-11 43.3 0.6 1.9e-10 41.0 0.2 2.2 2 0 0 2 2 2 1 ZU5 domain BTAD PF03704.17 PVD36584.1 - 0.0019 18.6 0.6 0.004 17.6 0.6 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain zf-C3HC4_3 PF13920.6 PVD36584.1 - 0.0026 17.6 7.2 0.0026 17.6 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36584.1 - 0.022 14.9 4.8 0.022 14.9 4.8 2.0 2 0 0 2 2 2 0 B-box zinc finger His_Phos_2 PF00328.22 PVD36584.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Prok-RING_4 PF14447.6 PVD36584.1 - 0.2 11.5 9.8 0.61 10.0 9.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PVD36584.1 - 0.23 11.3 11.0 0.38 10.7 8.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36584.1 - 0.52 10.7 11.9 1.6 9.2 9.5 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 PVD36584.1 - 3.2 7.8 10.1 0.3 11.1 5.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36584.1 - 6.2 6.9 12.0 7.6 6.6 8.5 2.7 2 0 0 2 2 2 0 zinc-RING finger domain CTK3 PF12243.8 PVD36585.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Tir_receptor_C PF07489.11 PVD36586.1 - 3.8 7.4 7.3 4.5 7.2 7.2 1.3 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF4328 PF14219.6 PVD36587.1 - 0.0052 16.4 0.5 0.0052 16.4 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) Myc_target_1 PF15179.6 PVD36587.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 LURAP PF14854.6 PVD36587.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF3311 PF11755.8 PVD36587.1 - 0.5 10.3 6.4 4.6 7.3 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) WAP PF00095.21 PVD36588.1 - 0.024 15.0 14.6 0.024 15.0 14.6 2.0 2 1 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' SEA PF01390.20 PVD36589.1 - 6.1e-19 68.1 5.8 7.1e-13 48.6 0.1 5.1 4 0 0 4 4 4 3 SEA domain PsbH PF00737.20 PVD36589.1 - 0.023 14.4 0.5 0.077 12.7 0.5 1.9 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein SIT PF15330.6 PVD36589.1 - 0.035 14.5 1.0 2.9 8.4 0.0 3.9 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT UPF0158 PF03682.13 PVD36589.1 - 0.24 11.4 0.4 23 4.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Adeno_E3_CR2 PF02439.15 PVD36589.1 - 0.25 11.1 4.9 0.59 9.9 4.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PBP5_C PF07943.13 PVD36591.1 - 0.1 12.8 1.0 7.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain SPATA6 PF14909.6 PVD36592.1 - 0.027 14.6 0.2 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Gemini_AC4_5_2 PF08464.10 PVD36592.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Ig_3 PF13927.6 PVD36594.1 - 5.6e-25 87.8 3.2 3.8e-08 33.8 0.1 4.3 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 PVD36594.1 - 7e-21 74.1 3.7 6e-09 35.9 0.1 4.8 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD36594.1 - 1.1e-12 48.1 5.9 2.3e-05 24.6 0.1 4.3 3 1 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD36594.1 - 5.3e-11 42.5 4.2 5.3e-05 23.3 0.1 4.3 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD36594.1 - 3.5e-08 33.6 4.3 0.013 15.6 0.1 4.4 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD36594.1 - 3e-05 23.5 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 PVD36594.1 - 0.00024 21.3 0.0 0.45 10.8 0.0 2.8 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 PVD36594.1 - 0.08 13.0 0.5 5.2 7.2 0.0 3.2 3 0 0 3 3 3 0 C17orf99 Ig domain Toxin_TOLIP PF00087.21 PVD36594.1 - 0.51 10.6 6.4 1.3 9.3 6.4 1.7 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Mito_fiss_reg PF05308.11 PVD36594.1 - 6 6.9 5.0 2.3 8.3 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_transf_10 PF00852.19 PVD36595.1 - 8.3e-36 123.3 0.2 1.4e-35 122.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD36595.1 - 8.2e-14 52.0 0.0 2.8e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal ADAM_CR PF08516.12 PVD36595.1 - 0.056 13.9 2.4 1.1 9.6 0.5 2.3 2 0 0 2 2 2 0 ADAM cysteine-rich Dicty_REP PF05086.12 PVD36597.1 - 0.46 8.4 1.2 0.59 8.0 1.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Trypsin PF00089.26 PVD36598.1 - 4.4e-43 147.7 0.0 6.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin LRAT PF04970.13 PVD36598.1 - 5.6e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF1986 PF09342.11 PVD36598.1 - 0.00067 20.0 0.0 0.0021 18.4 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) RhoGEF PF00621.20 PVD36599.1 - 8e-32 111.0 6.0 1.9e-31 109.7 6.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 PVD36599.1 - 4.2e-05 23.7 0.4 0.00022 21.3 0.4 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 PVD36599.1 - 5.5e-05 23.0 0.4 0.00059 19.7 0.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain RBD PF02196.15 PVD36599.1 - 0.00016 21.7 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain PH_10 PF15411.6 PVD36599.1 - 0.0043 17.3 0.1 0.029 14.6 0.1 2.5 1 0 0 1 1 1 1 Pleckstrin homology domain EGF_CA PF07645.15 PVD36599.1 - 0.13 12.5 0.4 0.56 10.5 0.4 2.1 1 0 0 1 1 1 0 Calcium-binding EGF domain Asp_protease PF09668.10 PVD36600.1 - 4e-59 197.8 0.9 6.4e-59 197.2 0.9 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PVD36600.1 - 7e-26 90.6 0.0 1.6e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PVD36600.1 - 3e-10 40.6 0.0 7.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 PVD36600.1 - 3.2e-07 30.2 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 PVD36600.1 - 9.2e-05 22.7 0.1 0.0002 21.6 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 PVD36600.1 - 0.0088 15.9 0.5 0.026 14.4 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UIM PF02809.20 PVD36600.1 - 0.032 14.1 3.0 0.032 14.1 3.0 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Metal_resist PF13801.6 PVD36600.1 - 7.7 6.7 11.3 0.67 10.1 2.4 2.8 3 0 0 3 3 3 0 Heavy-metal resistance Alk_phosphatase PF00245.20 PVD36601.1 - 8.3e-109 364.3 0.0 1.1e-108 363.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase HELP PF03451.14 PVD36602.1 - 2e-21 75.6 0.0 5.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 HELP motif DCX PF03607.17 PVD36602.1 - 2.4e-18 66.0 0.0 1e-11 44.8 0.0 2.9 2 0 0 2 2 2 2 Doublecortin WD40 PF00400.32 PVD36602.1 - 5.4e-10 39.7 8.3 0.0023 18.7 0.0 7.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36602.1 - 1.2e-08 35.1 0.9 0.00044 20.5 0.1 4.8 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PVD36602.1 - 2.9e-05 23.8 0.1 0.00011 21.8 0.1 2.0 1 0 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 PVD36602.1 - 0.026 13.9 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain IceA2 PF05862.11 PVD36602.1 - 0.033 14.1 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein MMS1_N PF10433.9 PVD36602.1 - 0.034 12.8 0.0 1.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SGL PF08450.12 PVD36602.1 - 0.11 12.1 0.2 0.53 9.8 0.0 2.2 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region His_Phos_2 PF00328.22 PVD36604.1 - 1.7e-15 57.3 0.1 1.1e-08 34.9 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cadherin PF00028.17 PVD36606.1 - 3.2e-14 53.1 0.0 9.4e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 PVD36606.1 - 3.9e-09 36.8 0.0 2.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PVD36606.1 - 0.011 16.3 0.0 0.035 14.7 0.0 1.9 1 0 0 1 1 1 0 Laminin G domain Cadherin_C_2 PF16492.5 PVD36606.1 - 0.024 15.4 0.0 0.08 13.7 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Ribosomal_L13 PF00572.18 PVD36606.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L13 LRR_8 PF13855.6 PVD36607.1 - 5.2e-24 83.8 16.3 2e-14 53.1 1.5 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD36607.1 - 2.1e-14 53.4 20.3 1.5e-05 25.3 0.3 4.8 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) I-set PF07679.16 PVD36607.1 - 1.1e-06 28.5 0.0 4.2e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD36607.1 - 2.9e-06 27.8 0.0 7.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 PVD36607.1 - 3e-05 24.0 15.0 1.8 9.4 0.1 7.0 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 PVD36607.1 - 6.5e-05 22.5 4.8 0.00053 19.5 1.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_5 PF13306.6 PVD36607.1 - 8.1e-05 22.6 0.0 0.00031 20.7 0.0 1.9 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PVD36607.1 - 9e-05 22.2 14.1 0.34 11.1 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich repeat ig PF00047.25 PVD36607.1 - 0.12 12.6 0.2 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain 7tm_7 PF08395.12 PVD36609.1 - 3.3e-06 26.6 0.5 3.3e-06 26.6 0.5 2.1 1 1 1 2 2 2 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 PVD36609.1 - 1.3e-05 24.1 3.0 0.00013 20.8 0.0 2.0 2 0 0 2 2 2 2 Trehalose receptor Neur_chan_memb PF02932.16 PVD36609.1 - 0.045 13.8 0.9 0.059 13.4 0.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HemY_N PF07219.13 PVD36609.1 - 3.1 8.0 5.3 0.39 10.9 0.2 2.0 2 0 0 2 2 2 0 HemY protein N-terminus LtrA PF06772.11 PVD36612.1 - 0.0002 20.7 2.1 0.00024 20.4 2.1 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Nup188_C PF18378.1 PVD36612.1 - 0.025 13.4 0.1 0.032 13.1 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Cation_efflux PF01545.21 PVD36612.1 - 0.34 10.6 9.7 0.17 11.6 7.6 1.5 2 0 0 2 2 2 0 Cation efflux family DUF308 PF03729.13 PVD36612.1 - 0.77 10.1 16.0 1.2 9.5 7.2 2.6 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) SRPRB PF09439.10 PVD36613.1 - 4.9e-57 192.3 0.2 5.9e-57 192.0 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PVD36613.1 - 3.9e-15 55.7 0.0 5.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD36613.1 - 6.5e-08 32.6 0.1 1.2e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD36613.1 - 1.7e-06 27.6 0.1 2.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PVD36613.1 - 4.9e-05 23.0 0.2 0.0065 16.0 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 PVD36613.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PVD36613.1 - 0.00053 20.2 0.0 0.00084 19.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Homeodomain PF00046.29 PVD36616.1 - 8.9e-24 83.1 7.2 1.6e-23 82.3 7.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD36616.1 - 1.3e-05 25.0 0.8 4.2e-05 23.3 0.8 1.9 1 0 0 1 1 1 1 Homeobox KN domain OAR PF03826.17 PVD36616.1 - 0.042 13.7 0.4 0.085 12.7 0.4 1.5 1 0 0 1 1 1 0 OAR domain 7TM_GPCR_Srw PF10324.9 PVD36617.1 - 2.4e-18 66.5 16.3 6.7e-18 65.0 16.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srw PF10324.9 PVD36618.1 - 5.6e-25 88.3 30.6 1.5e-24 86.9 30.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD36618.1 - 0.001 18.5 23.3 0.0015 17.9 23.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAM83 PF07894.12 PVD36618.1 - 0.0042 16.7 0.7 0.0087 15.6 0.7 1.4 1 0 0 1 1 1 1 FAM83 A-H SCIMP PF15050.6 PVD36618.1 - 0.13 12.7 0.1 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 SCIMP protein NIT PF08376.10 PVD36619.1 - 0.00012 22.7 0.1 0.00015 22.3 0.1 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing Guanylate_cyc PF00211.20 PVD36620.1 - 1.6e-21 76.7 0.1 3e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD36620.1 - 2.3e-07 30.5 0.8 7.4e-07 28.8 0.2 2.0 2 0 0 2 2 2 1 Heme NO binding associated NIT PF08376.10 PVD36620.1 - 0.00058 20.4 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 2 1 Nitrate and nitrite sensing AI-2E_transport PF01594.16 PVD36620.1 - 0.0069 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 AI-2E family transporter DUF668 PF05003.12 PVD36620.1 - 0.14 12.6 0.2 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Peptidase_M13_N PF05649.13 PVD36621.1 - 1.4e-121 406.8 0.3 1.8e-121 406.4 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36621.1 - 4.8e-75 251.7 0.3 8.9e-75 250.8 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 PVD36621.1 - 0.0077 16.0 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M48 DUF3134 PF11332.8 PVD36621.1 - 0.071 13.4 0.1 0.41 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) Endotoxin_C2 PF18449.1 PVD36621.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Delta endotoxin Peptidase_M13_N PF05649.13 PVD36622.1 - 1.6e-99 334.2 6.7 1.4e-88 298.1 0.6 2.6 2 1 1 3 3 3 2 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36622.1 - 1.7e-41 142.1 0.1 6.4e-22 78.2 0.2 2.9 1 1 1 2 2 2 2 Peptidase family M13 EF-hand_1 PF00036.32 PVD36622.1 - 1.4e-09 36.8 9.7 0.00017 20.9 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PVD36622.1 - 3e-08 34.0 1.6 1.4e-07 31.9 1.6 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD36622.1 - 3.9e-08 32.6 2.9 0.00053 19.7 1.5 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PVD36622.1 - 2.6e-05 24.0 0.4 0.00011 22.0 0.4 2.2 1 0 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD36622.1 - 0.0026 18.1 0.2 0.0026 18.1 0.2 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 PVD36622.1 - 0.013 14.9 3.2 0.35 10.4 0.2 2.9 2 0 0 2 2 2 0 EF hand Selenoprotein_S PF06936.11 PVD36622.1 - 1.4 8.7 7.5 2.6 7.8 7.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) 7tm_2 PF00002.24 PVD36623.1 - 4e-31 108.2 14.2 1.8e-30 106.0 10.6 2.8 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) SP_C-Propep PF08999.10 PVD36623.1 - 0.051 13.4 0.8 0.15 11.9 0.8 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ODV-E18 PF10717.9 PVD36623.1 - 0.058 13.3 1.0 0.14 12.0 1.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glyco_hydro_9 PF00759.19 PVD36624.1 - 1.1e-134 450.0 16.1 1.3e-134 449.7 16.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 PVD36625.1 - 3.9e-92 309.8 3.4 7.4e-92 308.9 3.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Ank_2 PF12796.7 PVD36625.1 - 1.5e-11 44.7 0.0 9.2e-11 42.2 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD36625.1 - 2.3e-11 43.6 0.3 7.4e-05 23.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PVD36625.1 - 2.8e-10 40.5 0.1 1.5e-05 25.5 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD36625.1 - 4.7e-10 39.5 0.1 1.9e-07 31.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD36625.1 - 1.5e-06 28.0 0.1 0.00048 20.4 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat CBM_2 PF00553.19 PVD36625.1 - 8.9e-06 25.9 2.1 2e-05 24.8 0.6 2.2 2 0 0 2 2 2 1 Cellulose binding domain Tmemb_185A PF10269.9 PVD36626.1 - 1.6e-56 191.8 25.6 2.4e-56 191.2 25.6 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Ufd2P_core PF10408.9 PVD36627.1 - 9.9e-192 638.9 13.8 1.2e-191 638.6 13.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 PVD36627.1 - 1.6e-21 76.2 0.5 7.4e-21 74.1 0.6 2.2 2 0 0 2 2 2 1 U-box domain DUF465 PF04325.13 PVD36627.1 - 0.15 12.1 0.0 0.5 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) TPT PF03151.16 PVD36628.1 - 1e-73 248.2 21.3 1.3e-73 247.9 21.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PVD36628.1 - 2.7e-09 37.3 29.1 3.2e-06 27.3 13.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PVD36628.1 - 2.4e-07 30.3 23.0 3.9e-07 29.6 23.0 1.3 1 0 0 1 1 1 1 UAA transporter family DUF2551 PF10826.8 PVD36628.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Herpes_capsid PF06112.11 PVD36629.1 - 1.2 9.2 7.3 3.1 7.9 7.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Keratin_2_head PF16208.5 PVD36632.1 - 0.02 15.0 9.8 0.025 14.7 9.8 1.1 1 0 0 1 1 1 0 Keratin type II head Toxin_20 PF08089.11 PVD36635.1 - 0.23 11.6 2.5 0.71 10.0 0.2 2.0 2 0 0 2 2 2 0 Huwentoxin-II family DcuA_DcuB PF03605.14 PVD36637.1 - 0.0036 16.2 1.2 0.97 8.3 0.1 2.2 2 0 0 2 2 2 2 Anaerobic c4-dicarboxylate membrane transporter UreE_N PF02814.15 PVD36637.1 - 0.023 14.3 0.0 5.6 6.6 0.0 3.1 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain Neurokinin_B PF03823.14 PVD36637.1 - 0.035 14.1 0.5 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Neurokinin B Tn7_Tnp_TnsA_C PF08721.11 PVD36637.1 - 0.15 12.7 0.0 63 4.3 0.0 3.0 3 0 0 3 3 3 0 TnsA endonuclease C terminal DIM PF08194.12 PVD36637.1 - 0.78 10.0 9.5 4.9 7.4 0.1 3.6 3 0 0 3 3 3 0 DIM protein YABBY PF04690.13 PVD36637.1 - 2.4 8.7 8.3 29 5.2 0.1 4.1 3 3 2 5 5 5 0 YABBY protein DUF5437 PF17505.2 PVD36638.1 - 0.017 15.1 0.6 28 4.8 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5437) Neurokinin_B PF03823.14 PVD36638.1 - 0.037 14.1 2.2 7.5 6.7 0.1 3.6 3 0 0 3 3 3 0 Neurokinin B XdhC_CoxI PF02625.16 PVD36638.1 - 0.083 13.1 1.1 9.3 6.5 0.1 3.0 3 0 0 3 3 3 0 XdhC and CoxI family YopE PF03545.13 PVD36638.1 - 0.089 13.0 0.0 10 6.4 0.0 2.9 3 0 0 3 3 3 0 Yersinia virulence determinant (YopE) DUF1686 PF07937.11 PVD36638.1 - 0.25 11.2 4.9 0.34 10.8 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1686) Toxin_2 PF00451.19 PVD36638.1 - 0.26 11.6 14.5 23 5.4 0.0 5.2 5 0 0 5 5 5 0 Scorpion short toxin, BmKK2 Lectin_N PF03954.14 PVD36638.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.5 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Sid-5 PF17204.3 PVD36638.1 - 0.52 10.5 3.5 1.8 8.8 0.1 2.7 3 0 0 3 3 3 0 Sid-5 family DUF326 PF03860.16 PVD36638.1 - 1.8 8.6 17.0 2 8.5 2.2 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF326) DIM PF08194.12 PVD36638.1 - 6.2 7.1 13.9 2.8 8.2 0.1 3.6 3 1 0 3 3 3 0 DIM protein Toxin_2 PF00451.19 PVD36639.1 - 0.047 14.0 0.5 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Cation_efflux PF01545.21 PVD36640.1 - 6.1e-22 78.3 4.9 8.6e-22 77.9 4.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PVD36640.1 - 3.6e-08 33.4 0.1 7.5e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter 7TM_GPCR_Srw PF10324.9 PVD36641.1 - 4.8e-25 88.5 15.2 9.4e-25 87.5 15.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD36641.1 - 9.7e-15 54.6 15.6 1.4e-14 54.0 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GSK-3_bind PF05350.12 PVD36641.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Gallidermin PF02052.15 PVD36641.1 - 0.11 12.8 1.4 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Gallidermin CopD PF05425.13 PVD36641.1 - 1.4 9.4 6.8 6 7.3 0.9 2.5 2 0 0 2 2 2 0 Copper resistance protein D Voltage_CLC PF00654.20 PVD36642.1 - 1.6e-81 274.3 24.8 1.6e-81 274.3 24.8 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PVD36642.1 - 0.00013 22.3 0.0 0.063 13.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain ABC_trans_CmpB PF06541.11 PVD36642.1 - 0.0044 17.3 1.9 0.0044 17.3 1.9 2.4 2 1 0 2 2 2 1 Putative ABC-transporter type IV Voltage_CLC PF00654.20 PVD36643.1 - 1.6e-79 267.7 26.9 2.5e-79 267.1 26.9 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel ABC_trans_CmpB PF06541.11 PVD36643.1 - 0.0058 16.9 3.3 0.0058 16.9 3.3 2.4 2 0 0 2 2 2 1 Putative ABC-transporter type IV CBS PF00571.28 PVD36643.1 - 0.042 14.3 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 CBS domain Phage_holin_2_1 PF04971.12 PVD36643.1 - 0.11 12.6 0.1 3.1 7.9 0.3 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S Phage_holin_3_1 PF05106.12 PVD36643.1 - 0.15 12.6 5.4 1.2 9.6 0.0 3.7 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) hSac2 PF12456.8 PVD36644.1 - 1e-20 73.5 0.1 1.7e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Inositol phosphatase ANAPC4_WD40 PF12894.7 PVD36645.1 - 0.00065 20.0 0.0 0.061 13.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD36645.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 PVD36645.1 - 0.0031 18.3 0.1 3.7 8.6 0.0 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 PVD36646.1 - 0.00035 21.3 1.6 16 6.6 0.0 4.0 3 1 1 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 PVD36646.1 - 0.00052 19.9 0.0 0.057 13.3 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PVD36646.1 - 0.0067 16.3 0.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF5645 PF18713.1 PVD36646.1 - 0.065 13.5 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5645) P53_TAD PF08563.11 PVD36647.1 - 0.00016 21.1 0.4 0.00029 20.2 0.4 1.4 1 0 0 1 1 1 1 P53 transactivation motif P53 PF00870.18 PVD36648.1 - 4.7e-43 147.2 0.4 2.5e-24 86.1 0.1 2.2 2 0 0 2 2 2 2 P53 DNA-binding domain P53_tetramer PF07710.11 PVD36648.1 - 1.5e-13 49.8 0.1 1.5e-13 49.8 0.1 1.9 2 0 0 2 2 2 1 P53 tetramerisation motif SAM_2 PF07647.17 PVD36648.1 - 4.2e-10 39.6 0.1 8.9e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD36648.1 - 8.4e-08 32.5 0.3 1.5e-07 31.7 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CSD PF00313.22 PVD36649.1 - 6.8e-07 29.0 0.1 1.2e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF543 PF04418.12 PVD36650.1 - 4e-26 90.8 0.2 4.5e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 PVD36650.1 - 0.0022 18.1 0.0 0.0026 17.9 0.0 1.1 1 0 0 1 1 1 1 ABC-type cobalt transport system, permease component Bacteriocin_IIc PF10439.9 PVD36650.1 - 0.0094 16.1 0.6 0.016 15.3 0.6 1.3 1 1 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide COesterase PF00135.28 PVD36651.1 - 1.4e-78 265.0 0.1 2e-78 264.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family eIF-5a PF01287.20 PVD36651.1 - 3.8e-25 87.8 0.4 6.2e-25 87.1 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Abhydrolase_3 PF07859.13 PVD36651.1 - 7e-10 39.1 0.2 4.3e-09 36.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD36651.1 - 0.0016 18.0 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family EFP_N PF08207.12 PVD36651.1 - 0.0028 17.6 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain COesterase PF00135.28 PVD36652.1 - 3.4e-129 432.0 0.0 3.1e-123 412.4 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36652.1 - 1.8e-08 34.5 0.1 7e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD36652.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 PVD36653.1 - 1.3e-16 60.6 0.2 1.5e-16 60.4 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 PVD36654.1 - 2.2e-91 307.3 0.0 1.4e-90 304.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36654.1 - 2.4e-08 34.1 0.3 1.1e-07 32.0 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_gyraseB PF00204.25 PVD36654.1 - 0.059 12.8 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase B COesterase PF00135.28 PVD36655.1 - 4.4e-127 425.1 0.0 5e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36655.1 - 1.1e-07 31.9 0.2 6.7e-07 29.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 PVD36656.1 - 5.9e-124 414.4 18.7 7.5e-124 414.0 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD36656.1 - 1e-30 106.8 21.0 2.6e-22 79.2 3.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT_4TMC PF16192.5 PVD36656.1 - 4.4 6.8 10.1 2.3 7.7 5.6 2.5 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase HLH PF00010.26 PVD36658.1 - 3.4e-15 55.7 3.1 6.8e-15 54.8 3.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 PVD36658.1 - 2.1e-10 40.6 0.2 2.1e-10 40.6 0.2 2.3 3 0 0 3 3 3 1 Hairy Orange zf-H2C2_2 PF13465.6 PVD36659.1 - 3.7e-12 46.1 103.1 0.00017 21.9 0.6 15.2 15 0 0 15 15 15 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD36659.1 - 7.2e-12 45.1 128.4 0.012 16.4 0.2 16.8 16 0 0 16 16 16 11 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD36659.1 - 2.7e-11 43.3 116.4 0.0016 18.8 0.3 16.1 16 0 0 16 16 16 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PVD36659.1 - 2.5e-08 34.0 41.8 0.002 18.3 0.5 9.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD36659.1 - 2.7e-05 24.4 61.2 0.12 12.8 0.4 11.9 12 0 0 12 12 12 5 Zinc-finger of C2H2 type Sybindin PF04099.12 PVD36660.1 - 5e-57 191.8 0.0 5.8e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PVD36660.1 - 1.6e-08 34.8 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PDZ_6 PF17820.1 PVD36660.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Leader_Erm PF08253.11 PVD36660.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Erm Leader peptide PIGA PF08288.12 PVD36661.1 - 4e-27 94.6 2.5 1.1e-26 93.3 2.5 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 PVD36661.1 - 4.1e-25 88.3 0.0 6.3e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD36661.1 - 1.3e-21 77.4 0.1 2.2e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PVD36661.1 - 3.9e-17 62.8 0.2 9.5e-17 61.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 PVD36661.1 - 0.0028 18.0 0.0 0.008 16.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Spermine_synth PF01564.17 PVD36662.1 - 3.8e-74 248.2 0.0 7.2e-74 247.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PVD36662.1 - 2.2e-23 81.9 0.1 4e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 PVD36662.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PVD36662.1 - 0.0014 19.3 0.0 0.0041 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD36662.1 - 0.0026 18.4 0.0 0.009 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PVD36662.1 - 0.0039 16.7 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 PVD36662.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GLTP PF08718.11 PVD36663.1 - 9.7e-63 210.9 0.3 3.1e-33 115.2 0.0 2.2 1 1 1 2 2 2 2 Glycolipid transfer protein (GLTP) CLN5 PF15014.6 PVD36663.1 - 0.015 15.0 0.1 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 5 CW_7 PF08230.11 PVD36663.1 - 0.081 12.7 1.8 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 CW_7 repeat SSF PF00474.17 PVD36664.1 - 1.1e-09 37.6 19.6 1.1e-09 37.6 19.6 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family Wzz PF02706.15 PVD36665.1 - 0.015 15.6 0.2 0.025 14.9 0.2 1.3 1 0 0 1 1 1 0 Chain length determinant protein DFF40 PF09230.10 PVD36666.1 - 5.7e-77 258.4 4.8 7.9e-77 257.9 4.8 1.2 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa CIDE-N PF02017.15 PVD36666.1 - 5.1e-29 100.1 0.2 1.2e-28 98.9 0.2 1.7 1 0 0 1 1 1 1 CIDE-N domain ING PF12998.7 PVD36666.1 - 0.0091 16.6 0.9 0.36 11.5 0.1 2.9 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding HNH PF01844.23 PVD36666.1 - 0.087 13.0 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 HNH endonuclease CCDC23 PF15674.5 PVD36668.1 - 0.00044 20.2 10.2 0.0013 18.7 9.6 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 23 p450 PF00067.22 PVD36669.1 - 9.6e-96 321.3 0.0 1.3e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD36670.1 - 7.1e-103 344.8 0.0 9.2e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ICMT PF04140.14 PVD36671.1 - 2.2e-29 101.7 0.3 4.1e-29 100.9 0.3 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PVD36671.1 - 5.4e-11 42.8 0.6 5.4e-11 42.8 0.6 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF4808 PF16066.5 PVD36672.1 - 2.7e-11 44.1 2.6 4.1e-11 43.5 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) Wzy_C_2 PF11846.8 PVD36672.1 - 0.0018 18.2 0.4 0.0022 17.9 0.4 1.0 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal gpUL132 PF11359.8 PVD36672.1 - 1.1 8.7 5.6 5.3 6.5 0.0 2.0 1 1 1 2 2 2 0 Glycoprotein UL132 MIF4G PF02854.19 PVD36673.1 - 4.2e-57 193.2 10.4 7.7e-57 192.3 9.4 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 PVD36673.1 - 2.8e-16 59.5 0.1 8e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 MA3 domain W2 PF02020.18 PVD36673.1 - 1.1e-13 51.1 0.2 9e-13 48.2 0.1 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PQ-loop PF04193.14 PVD36674.1 - 2.7e-26 91.1 12.0 6.9e-13 48.2 2.3 3.0 2 0 0 2 2 2 2 PQ loop repeat UPF0542 PF15086.6 PVD36674.1 - 0.1 12.6 0.1 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PI3Ka PF00613.20 PVD36676.1 - 2.4e-58 196.6 0.4 4.5e-58 195.7 0.4 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PVD36676.1 - 2.1e-53 181.7 0.2 2e-52 178.5 0.2 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 PVD36676.1 - 9.4e-30 102.2 0.1 2.4e-29 100.9 0.1 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 PVD36676.1 - 2.2e-20 73.0 0.0 5.5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 PVD36676.1 - 6.6e-19 68.0 0.1 2.6e-17 62.9 0.1 2.8 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain C2 PF00168.30 PVD36676.1 - 0.0013 19.0 0.0 0.0043 17.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain DUF4135 PF13575.6 PVD36676.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF1967 PF09269.11 PVD36676.1 - 0.091 12.7 0.1 19 5.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) zf-C2H2_2 PF12756.7 PVD36677.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Acyl-thio_N PF12590.8 PVD36677.1 - 0.88 10.1 5.0 3.1 8.4 0.4 3.2 2 0 0 2 2 2 0 Acyl-ATP thioesterase zf-met PF12874.7 PVD36677.1 - 6.7 7.3 8.7 0.78 10.2 3.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-met PF12874.7 PVD36678.1 - 2.1e-09 37.4 8.0 7e-05 23.1 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD36678.1 - 4.8e-08 33.1 5.7 0.0016 18.6 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PVD36678.1 - 0.0008 19.7 8.3 0.041 14.2 1.4 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Aminotran_4 PF01063.19 PVD36678.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Amino-transferase class IV zf-C2H2_4 PF13894.6 PVD36678.1 - 0.029 15.2 2.4 2.6 9.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 PVD36678.1 - 0.041 13.7 8.5 0.08 12.7 0.2 2.9 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2 PF00096.26 PVD36678.1 - 0.1 13.1 4.2 1 9.9 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PVD36678.1 - 1.1 9.4 5.7 13 5.9 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Cript PF10235.9 PVD36678.1 - 4 8.1 7.3 5.8 7.6 1.8 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF2175 PF09943.9 PVD36678.1 - 6.4 7.1 8.6 4.2 7.7 2.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) WD40 PF00400.32 PVD36679.1 - 9.8e-20 70.5 14.8 0.00016 22.4 0.2 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36679.1 - 8.9e-12 45.2 2.6 0.0031 17.8 0.3 4.3 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PVD36679.1 - 0.41 8.6 1.2 1.2 7.0 0.4 2.1 2 1 1 3 3 3 0 IKI3 family Ssu72 PF04722.13 PVD36680.1 - 2.2e-76 255.7 0.2 2.4e-76 255.6 0.2 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF1179 PF06678.11 PVD36681.1 - 0.61 10.1 3.8 0.45 10.5 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) UCH PF00443.29 PVD36682.1 - 1.5e-34 119.7 0.0 2.5e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD36682.1 - 7.9e-11 42.1 0.0 1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DiS_P_DiS PF06750.13 PVD36682.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.8 2 1 1 3 3 3 0 Bacterial Peptidase A24 N-terminal domain Copine PF07002.16 PVD36683.1 - 2.7e-65 219.9 0.0 1.4e-64 217.5 0.0 1.8 2 0 0 2 2 2 1 Copine vWA-TerF-like PF10138.9 PVD36683.1 - 2.6e-12 47.3 0.1 8.3e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus Gp_dh_C PF02800.20 PVD36684.1 - 3.9e-72 241.0 0.0 5.8e-72 240.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PVD36684.1 - 4.9e-39 132.8 0.1 1.2e-38 131.5 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 PVD36684.1 - 0.0045 16.4 0.1 0.0075 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 PVD36684.1 - 0.013 15.6 0.0 0.045 13.9 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1647 PF07801.11 PVD36685.1 - 4.8e-09 36.1 0.0 8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) PseudoU_synth_1 PF01416.20 PVD36686.1 - 9.3e-28 96.8 0.0 1.1e-26 93.4 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Neugrin PF06413.11 PVD36690.1 - 0.067 13.2 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Neugrin RCR PF12273.8 PVD36690.1 - 0.25 12.0 3.5 0.84 10.3 3.5 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HLH PF00010.26 PVD36691.1 - 1.7e-07 31.1 0.6 2.3e-07 30.7 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GH-E PF14410.6 PVD36691.1 - 0.016 15.6 0.3 0.022 15.1 0.3 1.3 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Phage_Gp23 PF10669.9 PVD36691.1 - 0.033 14.5 0.6 0.041 14.2 0.6 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Protamine_3 PF08188.11 PVD36691.1 - 0.034 14.3 4.6 0.057 13.6 4.6 1.4 1 0 0 1 1 1 0 Spermatozal protamine family Hairy_orange PF07527.13 PVD36692.1 - 0.021 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Hairy Orange HLH PF00010.26 PVD36692.1 - 0.066 13.2 0.6 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain LRR_9 PF14580.6 PVD36693.1 - 5.4e-06 26.0 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PVD36693.1 - 7.8e-05 23.0 14.0 0.00064 20.1 2.6 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD36693.1 - 0.1 12.4 8.2 0.27 11.0 2.4 2.9 2 1 1 3 3 3 0 Leucine rich repeat AAA_16 PF13191.6 PVD36694.1 - 0.00016 22.1 0.5 0.00089 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 PVD36694.1 - 0.012 16.0 0.1 0.06 13.8 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PVD36694.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PVD36694.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 PVD36694.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 PVD36695.1 - 9e-63 210.6 3.2 9e-63 210.6 3.2 3.1 3 0 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.23 PVD36695.1 - 1.4e-23 83.8 2.0 9.6e-23 81.1 0.0 2.8 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 PVD36695.1 - 8.9e-08 32.2 0.1 3.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 PVD36695.1 - 0.02 14.2 0.8 0.038 13.3 0.1 1.9 2 0 0 2 2 2 0 AIG1 family Mac PF12464.8 PVD36695.1 - 0.026 14.7 0.0 0.12 12.7 0.0 2.2 1 0 0 1 1 1 0 Maltose acetyltransferase DUF726 PF05277.12 PVD36695.1 - 0.16 10.9 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF4482 PF14818.6 PVD36695.1 - 0.2 12.5 0.2 0.2 12.5 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4482) PilJ PF13675.6 PVD36695.1 - 0.39 10.8 7.1 0.19 11.8 1.3 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RsgA_GTPase PF03193.16 PVD36695.1 - 0.43 10.5 3.6 0.68 9.8 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase DUF1664 PF07889.12 PVD36695.1 - 0.48 10.5 10.6 2.1 8.4 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 PVD36695.1 - 0.68 9.8 5.2 0.73 9.7 0.4 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF883 PF05957.13 PVD36695.1 - 0.87 10.2 8.6 40 4.9 3.0 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 PVD36695.1 - 1.1 9.2 7.7 4.4 7.3 0.8 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 PVD36695.1 - 1.6 9.2 10.1 1.2 9.6 0.1 3.7 3 2 1 4 4 4 0 ABC transporter AAA_23 PF13476.6 PVD36695.1 - 5.6 7.4 11.9 52 4.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain eIF-4B PF06273.11 PVD36695.1 - 6.5 5.7 8.5 2 7.4 2.5 2.4 3 0 0 3 3 3 0 Plant specific eukaryotic initiation factor 4B PDZ PF00595.24 PVD36696.1 - 2.9e-14 53.2 0.0 4.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD36696.1 - 2.2e-09 37.0 0.2 4.3e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD36696.1 - 0.0008 19.7 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 PVD36696.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain PI3K_C2 PF00792.24 PVD36697.1 - 0.01 15.8 0.2 0.77 9.7 0.0 2.7 2 1 0 2 2 2 0 Phosphoinositide 3-kinase C2 YojJ PF10372.9 PVD36697.1 - 0.75 9.9 10.6 0.68 10.1 1.3 3.8 2 1 3 5 5 5 0 Bacterial membrane-spanning protein N-terminus DUF983 PF06170.12 PVD36697.1 - 4 7.9 6.4 8.6 6.8 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF983) COG2 PF06148.11 PVD36697.1 - 4.3 7.4 11.3 0.83 9.7 1.9 3.1 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Forkhead PF00250.18 PVD36698.1 - 9.6e-39 131.5 0.0 1.7e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Menin PF05053.13 PVD36698.1 - 6.7 4.9 7.8 8.6 4.6 7.8 1.1 1 0 0 1 1 1 0 Menin Coatomer_WDAD PF04053.14 PVD36699.1 - 3.9e-171 570.0 0.0 8.1e-171 568.9 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 PVD36699.1 - 2.3e-39 132.7 3.1 5.2e-08 33.4 0.0 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD36699.1 - 1.6e-06 28.3 0.8 2.6 8.4 0.0 6.1 3 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD36699.1 - 2.4e-05 23.8 0.0 0.0018 17.7 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 PVD36699.1 - 0.00011 22.2 0.0 1.1 9.3 0.0 4.3 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ANF_receptor PF01094.28 PVD36700.1 - 2.3e-67 227.6 0.0 3.3e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD36700.1 - 1.8e-60 204.7 27.3 2.5e-60 204.2 27.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 PVD36700.1 - 1.4e-11 44.1 13.1 3.5e-11 42.9 13.1 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 PVD36700.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein HPS3_Mid PF14762.6 PVD36701.1 - 1.1e-66 225.2 0.3 2.9e-66 223.8 0.0 1.9 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 PVD36701.1 - 2.3e-47 161.3 1.2 4e-47 160.5 1.2 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 HPS3_C PF14763.6 PVD36701.1 - 1.4e-09 37.8 2.6 5.5e-09 35.8 2.6 2.0 1 1 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal Hydin_ADK PF17213.3 PVD36701.1 - 0.14 12.4 1.0 2 8.6 1.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF4805 PF16063.5 PVD36702.1 - 0.013 14.9 2.0 0.013 14.9 2.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4805) DMRT-like PF15791.5 PVD36702.1 - 0.098 13.1 0.0 4.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Nop14 PF04147.12 PVD36702.1 - 2 6.5 13.6 2.4 6.2 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family Parathyroid PF01279.17 PVD36702.1 - 3 8.5 6.7 1.1 9.9 0.4 2.5 1 1 0 2 2 2 0 Parathyroid hormone family GRA6 PF05084.13 PVD36702.1 - 6 6.8 11.2 9.5 6.1 11.2 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) MFS_1 PF07690.16 PVD36703.1 - 1e-99 333.8 41.3 6.9e-52 176.5 12.8 4.2 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36703.1 - 2.9e-19 69.3 43.4 6.8e-12 45.0 1.0 4.5 3 1 1 4 4 4 4 Sugar (and other) transporter ESSS PF10183.9 PVD36703.1 - 0.00015 22.0 0.7 1.8 8.8 0.1 3.9 3 0 0 3 3 3 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_2 PF13347.6 PVD36703.1 - 0.0036 15.9 1.4 0.0036 15.9 1.4 6.2 5 2 1 6 6 6 4 MFS/sugar transport protein Pex14_N PF04695.13 PVD36703.1 - 0.084 13.5 0.6 8.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPBP PF02517.16 PVD36703.1 - 3.2 8.2 8.5 18 5.8 0.1 4.5 3 0 0 3 3 3 0 CPBP intramembrane metalloprotease MFS_1 PF07690.16 PVD36704.1 - 2.5e-53 181.3 22.7 5.3e-50 170.3 19.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36704.1 - 4.5e-11 42.3 19.6 7.2e-10 38.3 6.3 2.5 2 2 0 2 2 2 2 Sugar (and other) transporter Chordopox_A13L PF05961.11 PVD36704.1 - 0.039 14.2 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ESSS PF10183.9 PVD36704.1 - 0.22 11.7 1.1 26 5.1 0.0 3.3 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_2 PF13347.6 PVD36704.1 - 0.32 9.5 15.8 0.04 12.5 2.7 3.4 2 1 1 3 3 3 0 MFS/sugar transport protein MFS_1 PF07690.16 PVD36705.1 - 9.6e-59 199.1 28.0 1.9e-54 185.0 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36705.1 - 2.9e-10 39.6 25.1 1e-08 34.5 25.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD36706.1 - 4.6e-50 170.5 10.7 1e-47 162.8 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36706.1 - 1e-10 41.1 14.6 3.7e-10 39.3 14.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Chordopox_A13L PF05961.11 PVD36706.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein MFS_1 PF07690.16 PVD36707.1 - 1.2e-75 254.7 41.7 7.1e-52 176.5 19.4 5.0 1 1 4 5 5 5 5 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36707.1 - 1.3e-17 63.9 22.3 5.4e-12 45.3 21.1 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter TFIIS_C PF01096.18 PVD36707.1 - 0.12 12.3 0.1 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) MFS_1 PF07690.16 PVD36708.1 - 4.4e-33 114.7 14.4 1.4e-25 90.0 3.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 PVD36709.1 - 4.2e-22 78.6 31.2 3.7e-16 59.0 16.8 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36709.1 - 3.2e-05 23.0 11.4 0.00033 19.7 7.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 PVD36709.1 - 0.039 12.2 4.4 0.036 12.3 2.2 1.9 2 0 0 2 2 2 0 BT1 family BCLP PF12304.8 PVD36709.1 - 0.087 12.4 3.0 1.7 8.2 0.2 2.6 2 0 0 2 2 2 0 Beta-casein like protein MFS_1 PF07690.16 PVD36710.1 - 3.2e-45 154.6 23.4 4.9e-43 147.4 15.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PVD36710.1 - 8.7e-05 22.0 1.2 8.7e-05 22.0 1.2 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 PVD36710.1 - 5.7 5.4 14.9 0.28 9.7 0.3 3.2 1 1 2 3 3 3 0 MFS/sugar transport protein MFS_1 PF07690.16 PVD36711.1 - 7.1e-30 104.1 6.7 1.8e-20 73.2 0.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36711.1 - 0.24 10.2 5.4 11 4.8 2.1 3.2 3 1 0 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 PVD36712.1 - 1.6e-11 43.7 4.7 3.6e-11 42.6 3.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36712.1 - 0.0027 16.6 0.4 0.0033 16.3 0.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD36713.1 - 2.6e-40 138.5 24.1 4.3e-39 134.5 17.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36713.1 - 0.00082 18.3 19.2 0.032 13.1 19.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.9 PVD36713.1 - 0.25 11.6 0.7 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 PVD36714.1 - 2.8e-52 177.8 20.7 2.9e-49 167.9 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD36714.1 - 3.3e-13 49.3 13.4 1e-11 44.4 6.2 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 PVD36714.1 - 9.1e-05 21.9 3.5 9.1e-05 21.9 3.5 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 PVD36714.1 - 0.0014 16.9 1.9 0.0092 14.3 0.0 2.1 2 0 0 2 2 2 1 BT1 family MFS_2 PF13347.6 PVD36714.1 - 0.01 14.4 13.0 0.028 13.0 1.7 3.4 2 1 1 3 3 3 0 MFS/sugar transport protein ubiquitin PF00240.23 PVD36715.1 - 6.9e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Arm PF00514.23 PVD36715.1 - 6.6e-06 26.0 3.2 0.29 11.2 0.0 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 PVD36715.1 - 6.8e-05 22.0 5.2 0.0022 17.0 2.6 2.7 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 PVD36715.1 - 0.0018 17.8 1.4 0.98 8.8 0.1 2.4 2 0 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 PVD36715.1 - 0.01 15.2 5.0 0.011 15.1 1.9 2.2 1 1 1 2 2 2 0 V-ATPase subunit H HEAT_2 PF13646.6 PVD36715.1 - 0.058 13.8 2.1 1 9.8 0.5 3.4 3 1 1 4 4 4 0 HEAT repeats Rad60-SLD PF11976.8 PVD36715.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rer1 PF03248.13 PVD36716.1 - 5.8e-65 218.2 5.2 6.9e-65 217.9 5.2 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 PVD36716.1 - 0.0072 16.0 0.8 0.0072 16.0 0.8 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2208) TMF_DNA_bd PF12329.8 PVD36717.1 - 0.0038 17.2 6.4 0.0038 17.2 6.4 14.9 4 2 12 17 17 17 1 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 PVD36717.1 - 0.012 15.9 1.2 0.012 15.9 1.2 11.5 12 3 1 13 13 13 0 TSC-22/dip/bun family PALP PF00291.25 PVD36718.1 - 9e-65 219.0 0.1 1e-64 218.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MTHFR PF02219.17 PVD36719.1 - 1.9e-89 299.8 0.0 8.7e-55 186.1 0.0 2.1 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase DUF1647 PF07801.11 PVD36720.1 - 7.1e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) AAR2 PF05282.11 PVD36721.1 - 2.3e-113 379.2 0.3 2.8e-113 378.9 0.3 1.1 1 0 0 1 1 1 1 AAR2 protein SNARE PF05739.19 PVD36721.1 - 0.28 11.2 0.5 0.8 9.8 0.5 1.7 1 0 0 1 1 1 0 SNARE domain COX16 PF14138.6 PVD36721.1 - 1.3 9.5 3.9 0.4 11.2 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Reprolysin_5 PF13688.6 PVD36722.1 - 3.6e-19 69.7 0.6 2.7e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 Metallo-peptidase family M12 Reprolysin PF01421.19 PVD36722.1 - 1e-16 61.5 0.9 4.8e-07 29.9 0.1 2.5 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 PVD36722.1 - 2.2e-16 60.5 0.0 8.1e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD36722.1 - 1.7e-15 57.4 1.4 3.1e-07 30.5 0.2 2.7 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 PVD36722.1 - 6.3e-14 51.9 37.8 9e-08 32.2 7.6 5.3 5 0 0 5 5 5 2 Thrombospondin type 1 domain Reprolysin_4 PF13583.6 PVD36722.1 - 1.9e-13 50.6 0.0 3.2e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD36722.1 - 4.5e-07 29.9 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 2 Matrixin ADAM_CR_2 PF17771.1 PVD36722.1 - 1.2e-06 28.9 9.0 1.9e-05 25.1 1.4 5.1 6 1 0 6 6 3 2 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 PVD36722.1 - 4.2e-05 23.8 0.0 8.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide DUF4215 PF13948.6 PVD36722.1 - 0.00015 22.1 0.3 1.1 9.7 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4215) Peptidase_M57 PF12388.8 PVD36722.1 - 0.00047 19.8 0.5 0.23 11.0 0.1 2.4 2 0 0 2 2 2 2 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 PVD36722.1 - 0.00087 19.0 0.0 0.96 9.0 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 PVD36722.1 - 0.0011 18.0 0.7 0.83 8.5 0.1 2.3 2 0 0 2 2 2 2 Peptidase M66 DUF4953 PF16313.5 PVD36722.1 - 0.061 12.5 2.5 2.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Met-zincin Metallopep PF12044.8 PVD36722.1 - 0.13 10.8 0.3 4.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Putative peptidase family DMA PF03474.14 PVD36722.1 - 0.17 11.5 1.2 22 4.8 0.0 3.0 3 0 0 3 3 3 0 DMRTA motif Tryp_inh PF17983.1 PVD36722.1 - 8.9 6.5 18.3 2.8 8.1 0.4 4.5 4 0 0 4 4 4 0 Trypsin inhibitors 1,2 and 3 Reprolysin PF01421.19 PVD36723.1 - 2.6e-12 47.1 0.1 4.3e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 PVD36723.1 - 4.4e-11 43.2 0.0 1.5e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 PVD36723.1 - 1.6e-10 41.5 0.0 2.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD36723.1 - 3.7e-07 30.7 0.0 8.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD36723.1 - 1.2e-06 28.6 0.1 2.1e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD36723.1 - 1.4e-05 24.9 0.4 3.5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD36723.1 - 0.0073 16.2 0.1 0.011 15.6 0.1 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 PVD36723.1 - 0.009 15.0 0.2 0.014 14.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 IBN_N PF03810.19 PVD36723.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Reprolysin PF01421.19 PVD36724.1 - 5.5e-11 42.8 0.0 8.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD36724.1 - 2e-10 41.1 0.1 4.7e-10 39.9 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PVD36724.1 - 2.1e-08 34.7 0.0 6.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD36724.1 - 2.7e-06 27.2 0.0 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PVD36724.1 - 3.4e-05 23.8 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 PVD36724.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 SARG PF15385.6 PVD36724.1 - 0.032 13.5 0.7 0.043 13.1 0.7 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Peptidase_M10 PF00413.24 PVD36724.1 - 0.038 13.9 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 PVD36725.1 - 3.5e-05 24.3 0.0 9.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD36725.1 - 0.0056 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD36725.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD36725.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 PVD36726.1 - 5.3e-05 23.7 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD36726.1 - 0.0014 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD36726.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD36726.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 PVD36727.1 - 4.1e-11 43.3 0.0 6.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 PVD36727.1 - 3.1e-06 27.3 14.3 6.2e-06 26.3 6.8 2.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 PVD36727.1 - 4.5e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD36727.1 - 5e-06 26.3 0.0 9.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD36727.1 - 0.00024 21.1 0.2 0.00058 19.8 0.2 1.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD36727.1 - 0.00028 21.1 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD36727.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD36727.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin ADAM_CR_2 PF17771.1 PVD36727.1 - 0.82 10.2 0.0 0.82 10.2 0.0 3.3 3 0 0 3 3 3 0 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 PVD36728.1 - 2.5e-21 76.4 1.0 1.8e-10 41.2 0.1 2.5 2 0 0 2 2 2 2 Reprolysin family propeptide Reprolysin PF01421.19 PVD36728.1 - 2e-15 57.3 0.4 1.2e-07 31.8 0.1 2.5 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 PVD36728.1 - 1.1e-14 55.0 1.0 6.3e-06 26.7 0.0 3.5 3 0 0 3 3 3 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD36728.1 - 1.4e-14 54.7 8.3 1.3e-06 28.7 0.0 3.6 2 1 1 3 3 3 2 Metallo-peptidase family M12 TSP_1 PF00090.19 PVD36728.1 - 3e-11 43.4 34.6 1.7e-06 28.2 8.1 4.9 4 0 0 4 4 4 2 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 PVD36728.1 - 1e-10 41.9 17.6 1.7e-09 38.0 2.5 5.7 6 2 0 6 6 4 2 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 PVD36728.1 - 2e-08 34.4 3.9 0.0029 17.5 0.1 3.2 3 0 0 3 3 3 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD36728.1 - 3.7e-08 33.3 4.3 0.0037 16.9 0.1 3.2 3 0 0 3 3 3 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD36728.1 - 8.5e-07 28.9 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 2 Matrixin Astacin PF01400.24 PVD36728.1 - 0.0006 19.5 0.2 0.68 9.5 0.1 2.5 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 PVD36728.1 - 0.01 14.8 0.3 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase M66 DUF4215 PF13948.6 PVD36728.1 - 0.019 15.4 3.5 3.8 8.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Peptidase_M57 PF12388.8 PVD36728.1 - 0.02 14.5 5.5 0.76 9.3 0.0 3.2 3 0 0 3 3 3 0 Dual-action HEIGH metallo-peptidase Uma2 PF05685.12 PVD36728.1 - 0.028 14.0 0.0 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative restriction endonuclease Peptidase_M60 PF13402.6 PVD36728.1 - 0.072 12.6 0.1 0.072 12.6 0.1 3.0 3 0 0 3 3 3 0 Peptidase M60, enhancin and enhancin-like DUF4953 PF16313.5 PVD36728.1 - 0.25 10.5 0.9 9.1 5.4 0.1 2.2 2 0 0 2 2 2 0 Met-zincin Dicty_REP PF05086.12 PVD36728.1 - 0.44 8.5 6.8 0.65 7.9 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 PVD36728.1 - 8.5 6.4 18.9 32 4.5 18.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UCH PF00443.29 PVD36729.1 - 5.5e-22 78.5 0.0 1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD36729.1 - 5.6e-09 36.0 4.0 4.1e-08 33.2 2.2 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Reprolysin_5 PF13688.6 PVD36729.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUSP PF06337.12 PVD36729.1 - 0.0016 19.0 0.0 0.046 14.3 0.0 3.0 3 0 0 3 3 3 1 DUSP domain ubiquitin PF00240.23 PVD36729.1 - 0.0086 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Reprolysin PF01421.19 PVD36729.1 - 0.043 13.7 1.9 0.47 10.3 0.1 2.5 1 1 1 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease UN_NPL4 PF11543.8 PVD36729.1 - 0.065 13.7 0.2 0.62 10.6 0.1 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 PVD36729.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Reprolysin_3 PF13582.6 PVD36729.1 - 0.078 13.5 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD36729.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Matrixin TisB_toxin PF13939.6 PVD36729.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system TLP-20 PF06088.11 PVD36729.1 - 4.2 7.2 5.6 6.3 6.7 1.4 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF932 PF06067.11 PVD36730.1 - 0.0042 16.9 2.4 0.0066 16.3 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF932) Adaptin_binding PF10199.9 PVD36730.1 - 0.033 14.8 0.7 0.033 14.8 0.7 2.4 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Pep_M12B_propep PF01562.19 PVD36731.1 - 1.4e-08 35.1 0.1 2.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 PVD36731.1 - 1.2e-05 25.4 0.6 1.2e-05 25.4 0.6 3.8 4 1 0 4 4 4 2 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 PVD36731.1 - 0.0001 22.7 0.3 0.0001 22.7 0.3 3.7 2 1 0 2 2 2 1 ADAM cysteine-rich domain SAM_2 PF07647.17 PVD36735.1 - 2.2e-23 82.2 0.3 1.5e-08 34.6 0.0 3.5 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD36735.1 - 9.4e-19 67.6 0.4 5.8e-07 29.9 0.0 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) FxsA PF04186.13 PVD36735.1 - 0.22 11.6 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein NPV_P10 PF05531.12 PVD36735.1 - 0.61 10.6 3.8 12 6.5 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 PVD36735.1 - 2.7 8.2 13.0 0.61 10.3 7.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 PVD36735.1 - 2.9 8.0 37.8 0.19 11.8 20.6 3.6 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 PVD36735.1 - 3.5 7.9 15.1 5.7 7.3 0.2 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 PVD36735.1 - 8.8 6.7 10.6 37 4.7 0.8 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) FAM181 PF15238.6 PVD36736.1 - 0.021 14.7 1.0 0.036 13.9 0.9 1.4 1 1 0 1 1 1 0 FAM181 Sulfotransfer_1 PF00685.27 PVD36737.1 - 1.8e-48 165.4 0.7 2.4e-47 161.7 0.7 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD36737.1 - 0.00092 19.7 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF778 PF05608.12 PVD36738.1 - 1.7e-41 142.7 6.8 1.2e-22 81.2 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Nuc_sug_transp PF04142.15 PVD36739.1 - 2.1e-06 27.2 0.7 3.3e-06 26.5 0.7 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 PVD36739.1 - 3.4e-06 26.6 4.5 4.8e-06 26.1 2.2 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 PVD36739.1 - 2.9e-05 24.3 16.4 0.00078 19.6 1.4 3.4 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 PVD36739.1 - 7.2e-05 21.9 1.4 7.2e-05 21.9 1.4 2.2 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like V_ATPase_I PF01496.19 PVD36739.1 - 0.095 10.6 0.0 0.15 10.0 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM234 PF10639.9 PVD36739.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.2 2 1 0 2 2 2 0 Putative transmembrane family 234 UAA PF08449.11 PVD36739.1 - 0.32 10.1 7.0 0.57 9.3 7.0 1.4 1 0 0 1 1 1 0 UAA transporter family YoqO PF14037.6 PVD36739.1 - 0.94 10.0 7.1 0.41 11.2 2.9 2.5 2 0 0 2 2 2 0 YoqO-like protein LRR_6 PF13516.6 PVD36740.1 - 2.3e-24 83.3 14.9 5.6e-07 29.1 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 PVD36740.1 - 0.0037 17.6 3.2 17 6.5 0.0 5.6 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 PVD36740.1 - 0.0046 16.7 8.6 0.55 10.0 0.3 4.9 3 3 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PVD36740.1 - 0.019 15.4 14.4 0.24 11.9 0.3 5.3 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) ATP-synt_D PF01813.17 PVD36741.1 - 2.8e-06 27.3 0.6 0.00012 22.0 0.6 2.2 1 1 0 1 1 1 1 ATP synthase subunit D DUF4615 PF15393.6 PVD36742.1 - 5.6e-11 43.2 10.0 1.1e-09 39.0 2.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4615) LRR_6 PF13516.6 PVD36743.1 - 1.2e-15 56.1 19.6 1.5e-05 24.7 0.0 6.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 PVD36743.1 - 7.2e-05 23.1 11.8 0.26 11.8 0.2 5.1 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD36743.1 - 0.0017 18.6 1.0 21 6.2 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 PVD36743.1 - 0.0048 16.6 6.9 1.2 8.9 0.3 5.3 3 1 3 6 6 6 2 Leucine rich repeat Periviscerokin PF08259.11 PVD36744.1 - 0.17 12.2 1.3 7.4 7.2 0.1 3.2 3 0 0 3 3 3 0 Periviscerokinin family SelK_SelG PF10961.8 PVD36745.1 - 0.0075 16.9 10.2 0.016 15.8 10.2 1.7 1 0 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 PVD36745.1 - 0.25 12.0 23.9 0.36 11.5 23.9 1.2 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 PVD36745.1 - 7.3 7.2 10.9 11 6.6 10.9 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Casein PF00363.18 PVD36746.1 - 0.077 13.4 2.4 0.2 12.0 2.4 1.7 1 0 0 1 1 1 0 Casein Pkinase PF00069.25 PVD36747.1 - 3.8e-21 75.7 0.0 7.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD36747.1 - 2.9e-17 62.8 0.0 5.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APC_u13 PF16634.5 PVD36747.1 - 0.024 14.5 0.1 0.08 12.9 0.1 1.9 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP 7tm_1 PF00001.21 PVD36749.1 - 2.9e-28 98.9 0.4 3.8e-28 98.6 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD36749.1 - 0.38 10.4 5.9 0.25 11.0 3.3 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD36750.1 - 1.2e-07 31.3 0.3 1.8e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD36750.1 - 0.00033 20.1 0.2 0.00044 19.7 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.9 PVD36750.1 - 0.039 12.9 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt PAX PF00292.18 PVD36755.1 - 2.4e-58 195.5 0.5 4.8e-58 194.5 0.5 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 PVD36755.1 - 1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 PVD36755.1 - 0.00011 22.7 0.1 0.0038 17.8 0.0 2.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 PVD36755.1 - 0.00039 20.5 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 PVD36755.1 - 0.00063 19.7 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix CDK2AP PF09806.9 PVD36755.1 - 1.3 9.0 4.6 2.7 8.0 4.6 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Lectin_C PF00059.21 PVD36757.1 - 3.3e-11 43.9 0.3 1.1e-10 42.3 0.0 2.0 2 1 0 2 2 2 1 Lectin C-type domain TipE PF16972.5 PVD36757.1 - 0.02 14.1 5.2 0.029 13.5 5.2 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE P4Ha_N PF08336.11 PVD36758.1 - 5.9e-19 68.4 0.1 1e-18 67.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 PVD36758.1 - 2.1e-13 51.0 0.0 4.5e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 PVD36758.1 - 2.5e-06 27.7 0.9 5.2e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD36758.1 - 8.9e-06 25.4 0.7 2.8e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD36758.1 - 5.9e-05 22.7 0.0 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PVD36758.1 - 0.00021 21.1 0.1 0.00066 19.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD36758.1 - 0.00025 21.0 0.0 0.00095 19.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD36758.1 - 0.0034 17.0 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 PVD36758.1 - 0.022 15.4 0.6 0.092 13.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD36758.1 - 0.03 14.2 0.7 0.03 14.2 0.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD36758.1 - 0.039 14.8 0.0 0.14 13.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD36758.1 - 0.1 13.3 0.2 0.3 11.8 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SATase_N PF06426.14 PVD36758.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal C2 PF00168.30 PVD36760.1 - 4e-22 78.4 0.9 5.9e-11 42.6 0.2 2.7 2 1 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 PVD36760.1 - 0.022 14.7 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 TMEM52 PF14979.6 PVD36760.1 - 0.05 13.5 0.3 0.12 12.2 0.3 1.7 1 1 0 1 1 1 0 Transmembrane 52 Tmem26 PF09772.9 PVD36761.1 - 1.1e-62 212.1 4.2 1.2e-62 211.8 4.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 Tmem26 PF09772.9 PVD36762.1 - 1.8e-17 63.6 4.0 2.8e-17 63.0 4.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.6 PVD36762.1 - 0.064 13.1 2.4 0.096 12.5 2.4 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family Bin3 PF06859.12 PVD36763.1 - 1.8e-25 89.6 0.0 5.5e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 PVD36763.1 - 1.1e-11 45.2 0.0 1.8e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PVD36763.1 - 2.7e-11 43.9 0.0 2.3e-09 37.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PVD36763.1 - 7.4e-11 42.7 0.0 2.1e-09 38.0 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD36763.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD36763.1 - 2.4e-09 37.2 0.0 1.4e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 PVD36763.1 - 1.4e-05 24.6 0.1 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 PVD36763.1 - 1.8e-05 24.8 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PVD36763.1 - 6.1e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PVD36763.1 - 0.00057 19.3 0.0 0.091 12.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PVD36763.1 - 0.0019 18.0 0.0 0.037 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PVD36763.1 - 0.0039 16.5 0.0 0.051 12.9 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 PVD36763.1 - 0.0059 16.1 0.2 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 PVD36763.1 - 0.0096 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 PVD36763.1 - 0.041 14.0 0.1 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 FtsJ-like methyltransferase SPRY PF00622.28 PVD36764.1 - 3.3e-18 65.9 0.0 5.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 PVD36764.1 - 2.4e-08 34.2 1.8 3.9e-08 33.5 1.8 1.4 1 0 0 1 1 1 1 SOCS box DUF1327 PF07041.11 PVD36765.1 - 0.022 14.8 0.3 0.043 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) DNA_pack_N PF02500.15 PVD36765.1 - 5.5 6.7 9.2 1.1 9.1 0.1 2.4 2 1 0 2 2 2 0 Probable DNA packing protein, N-terminus Cwf_Cwc_15 PF04889.12 PVD36766.1 - 0.66 9.7 7.9 1.8 8.2 7.9 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PMP22_Claudin PF00822.20 PVD36768.1 - 0.0037 17.1 0.5 0.0056 16.6 0.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SNF PF00209.18 PVD36770.1 - 5.6e-150 500.5 34.5 5.2e-149 497.3 34.6 1.9 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 PVD36771.1 - 7.2e-143 477.0 27.3 2.6e-140 468.6 23.3 2.3 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family SNF PF00209.18 PVD36772.1 - 9.5e-153 509.6 26.2 1.3e-90 304.6 11.7 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family LPP PF04728.13 PVD36775.1 - 0.51 10.8 6.3 0.99 9.8 0.2 4.2 4 1 0 4 4 4 0 Lipoprotein leucine-zipper TarH PF02203.15 PVD36775.1 - 0.76 9.7 8.3 0.22 11.4 3.1 2.6 2 1 0 2 2 2 0 Tar ligand binding domain homologue PI_PP_I PF18363.1 PVD36775.1 - 1.6 8.9 6.5 12 6.1 0.6 3.3 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF4250 PF14056.6 PVD36775.1 - 5.3 7.1 6.5 1.9 8.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Band_7 PF01145.25 PVD36776.1 - 2.4e-23 83.0 1.6 2.4e-23 83.0 1.6 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 PVD36776.1 - 0.00076 19.6 2.3 0.0016 18.5 2.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 MRP-L47 PF06984.13 PVD36777.1 - 3e-37 126.6 3.7 3e-37 126.6 3.7 1.7 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fumerase_C PF05683.12 PVD36778.1 - 1.3e-87 292.5 0.0 2.1e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 PVD36778.1 - 6.5e-87 291.4 0.0 8.8e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Kinesin PF00225.23 PVD36779.1 - 1.6e-114 382.3 0.0 2.7e-114 381.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 PVD36779.1 - 2.9e-63 213.3 5.7 2e-50 171.5 0.9 3.4 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 PVD36779.1 - 7.5e-39 133.9 0.2 3.7e-38 131.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 PVD36779.1 - 7.9e-24 84.3 0.1 2.5e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 PVD36779.1 - 4.5e-12 46.2 0.1 4.5e-12 46.2 0.1 2.9 3 0 0 3 3 3 1 Kinesin protein 1B PH PF00169.29 PVD36779.1 - 6.1e-09 36.3 0.0 5.2e-08 33.4 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 PVD36779.1 - 0.0031 17.9 5.4 0.0092 16.4 0.7 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 PVD36779.1 - 0.053 13.8 0.8 0.37 11.1 0.1 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 PVD36779.1 - 0.06 13.7 0.1 0.21 12.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2 PF00096.26 PVD36780.1 - 0.00012 22.3 11.9 0.015 15.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36780.1 - 1.9 9.6 12.6 1.9 9.6 1.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger TCL1_MTCP1 PF01840.17 PVD36781.1 - 0.059 13.0 1.2 0.32 10.6 0.3 2.3 2 0 0 2 2 2 0 TCL1/MTCP1 family zf-C2H2_4 PF13894.6 PVD36782.1 - 4.1e-06 27.2 32.7 0.2 12.6 3.4 6.7 5 0 0 5 5 5 4 C2H2-type zinc finger SET PF00856.28 PVD36782.1 - 0.00013 22.4 0.0 0.00013 22.4 0.0 3.8 3 2 0 3 3 3 1 SET domain zf-C2H2_8 PF15909.5 PVD36782.1 - 0.0064 16.8 3.0 0.0064 16.8 3.0 4.1 2 1 0 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD36782.1 - 0.059 13.7 9.5 0.33 11.3 0.5 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PVD36782.1 - 0.077 13.5 37.6 0.73 10.4 4.0 6.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type CdiA_C PF18451.1 PVD36782.1 - 0.13 12.4 1.3 25 5.2 0.0 3.1 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain zf-met PF12874.7 PVD36782.1 - 2.7 8.5 18.0 0.9 10.0 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF4686 PF15742.5 PVD36783.1 - 1.7e-30 106.4 76.6 1.7e-30 106.4 76.6 8.0 2 1 4 7 7 7 1 Domain of unknown function (DUF4686) Ank_2 PF12796.7 PVD36783.1 - 9.8e-15 54.9 2.7 1.6e-05 25.4 0.1 6.1 4 1 1 6 6 6 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD36783.1 - 3.1e-14 52.8 1.9 3.5e-05 24.0 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD36783.1 - 6.9e-12 45.3 2.0 2.2 8.9 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 PVD36783.1 - 8.2e-12 45.4 11.6 0.0011 19.5 0.2 7.5 4 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD36783.1 - 2.4e-08 33.6 2.5 15 6.6 0.0 8.3 9 0 0 9 9 9 1 Ankyrin repeat SOCS_box PF07525.16 PVD36783.1 - 0.00027 21.2 2.6 0.00027 21.2 2.6 2.1 2 0 0 2 2 2 1 SOCS box LigT_PEase PF02834.16 PVD36783.1 - 0.023 14.9 2.1 14 6.0 0.0 5.1 3 0 0 3 3 3 0 LigT like Phosphoesterase Hormone_recep PF00104.30 PVD36784.1 - 1.8e-08 34.2 0.5 1.1e-07 31.7 0.5 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor NRIP1_repr_4 PF15690.5 PVD36784.1 - 0.93 8.7 5.6 1.5 8.0 0.5 2.1 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 4 DUF515 PF04415.12 PVD36784.1 - 1.5 7.2 4.4 2.5 6.4 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hormone_recep PF00104.30 PVD36785.1 - 0.0021 17.7 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor NICE-1 PF15845.5 PVD36788.1 - 0.2 12.5 3.2 0.13 13.1 1.6 1.5 1 1 1 2 2 2 0 Cysteine-rich C-terminal 1 family APC_u15 PF16636.5 PVD36789.1 - 0.049 14.1 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 RuvC PF02075.17 PVD36790.1 - 0.063 13.2 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC WD40 PF00400.32 PVD36791.1 - 2.6e-10 40.7 0.4 4.1e-06 27.4 0.0 4.1 5 1 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 PVD36791.1 - 0.0056 15.4 0.4 0.017 13.8 0.3 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 CENP-B_dimeris PF09026.10 PVD36791.1 - 0.015 15.6 4.6 0.039 14.3 4.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40_like PF17005.5 PVD36791.1 - 0.039 13.3 0.1 0.18 11.1 0.1 1.9 1 1 1 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 PVD36791.1 - 0.06 13.6 0.2 0.91 9.9 0.1 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PMP22_Claudin PF00822.20 PVD36792.1 - 4.8e-06 26.5 3.0 5.7e-06 26.3 3.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD36792.1 - 0.00043 20.1 6.1 0.00058 19.7 6.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 PVD36792.1 - 0.0013 17.8 0.5 0.0016 17.5 0.5 1.3 1 0 0 1 1 1 1 Dual oxidase maturation factor PepSY_TM PF03929.16 PVD36792.1 - 0.011 15.4 0.4 0.029 14.0 0.1 1.7 2 0 0 2 2 2 0 PepSY-associated TM region Pkinase_Tyr PF07714.17 PVD36793.1 - 4.7e-84 281.7 0.0 1.3e-83 280.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36793.1 - 4.7e-47 160.6 0.0 9.1e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 PVD36793.1 - 0.0055 17.0 0.0 0.021 15.1 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain BORG_CEP PF14957.6 PVD36793.1 - 0.025 15.7 0.3 0.025 15.7 0.3 4.4 2 1 0 2 2 2 0 Cdc42 effector Haspin_kinase PF12330.8 PVD36793.1 - 0.041 12.8 0.0 0.087 11.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain DUF4984 PF16372.5 PVD36793.1 - 0.13 12.2 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4984) ANF_receptor PF01094.28 PVD36794.1 - 6.3e-18 65.0 0.0 1.2e-17 64.1 0.0 1.4 1 1 1 2 2 2 1 Receptor family ligand binding region RVT_1 PF00078.27 PVD36795.1 - 3.9e-26 91.9 0.3 5e-26 91.6 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 PVD36796.1 - 6.9e-32 110.7 0.0 9.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD36796.1 - 1.1e-25 90.6 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-B_box PF00643.24 PVD36797.1 - 4.7e-10 39.4 25.1 4.7e-06 26.7 4.0 3.0 3 0 0 3 3 2 2 B-box zinc finger FlxA PF14282.6 PVD36797.1 - 0.022 14.8 4.6 4.9 7.2 1.0 3.3 2 1 1 3 3 3 0 FlxA-like protein ArfGap PF01412.18 PVD36797.1 - 0.049 13.7 17.6 0.098 12.7 4.7 2.8 1 1 2 3 3 3 0 Putative GTPase activating protein for Arf DUF3450 PF11932.8 PVD36797.1 - 0.057 12.7 3.4 0.11 11.7 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cor1 PF04803.12 PVD36797.1 - 0.18 12.0 9.8 0.92 9.7 4.8 2.3 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF1664 PF07889.12 PVD36797.1 - 0.42 10.7 9.4 6.4 6.8 2.8 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) WRNPLPNID PF15017.6 PVD36797.1 - 0.47 11.4 7.4 1.7 9.5 7.4 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CM2 PF03021.14 PVD36797.1 - 0.99 9.2 3.6 15 5.4 2.2 2.7 2 0 0 2 2 2 0 Influenza C virus M2 protein Baculo_PEP_C PF04513.12 PVD36797.1 - 1.1 9.3 6.3 8 6.5 0.7 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 PVD36797.1 - 1.3 8.9 4.0 4.6 7.1 0.4 2.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 zf-C3HC4_3 PF13920.6 PVD36797.1 - 1.5 8.8 23.5 0.063 13.2 6.3 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.10 PVD36797.1 - 1.6 9.1 14.8 4.3 7.8 14.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1351 PF07083.11 PVD36797.1 - 1.8 8.3 9.0 23 4.6 0.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) FAM176 PF14851.6 PVD36797.1 - 2 8.1 8.0 1.5 8.5 1.5 2.5 2 0 0 2 2 2 0 FAM176 family DASH_Dad2 PF08654.10 PVD36797.1 - 2.4 8.6 7.3 17 5.9 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad2 DUF948 PF06103.11 PVD36797.1 - 2.6 8.4 5.2 34 4.8 0.2 3.0 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) zf-HIT PF04438.16 PVD36797.1 - 2.8 7.9 12.6 0.1 12.5 5.5 2.3 2 0 0 2 2 2 0 HIT zinc finger Zn_Tnp_IS91 PF14319.6 PVD36797.1 - 3.6 7.7 17.0 0.066 13.3 5.0 2.8 2 1 1 3 3 2 0 Transposase zinc-binding domain zf-B_box PF00643.24 PVD36798.1 - 3.3e-10 39.9 15.5 6.7e-07 29.4 2.8 3.8 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD36798.1 - 3.3e-09 36.5 6.1 3.3e-09 36.5 6.1 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36798.1 - 2e-08 34.5 7.6 2e-08 34.5 7.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36798.1 - 4.2e-08 32.9 9.4 4.2e-08 32.9 9.4 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36798.1 - 3.5e-07 30.0 10.0 3.5e-07 30.0 10.0 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD36798.1 - 4.6e-07 29.8 6.8 4.6e-07 29.8 6.8 3.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36798.1 - 4.7e-07 29.5 8.3 4.7e-07 29.5 8.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36798.1 - 1.2e-05 25.4 7.6 1.2e-05 25.4 7.6 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36798.1 - 0.00026 20.9 8.3 0.00026 20.9 8.3 3.8 3 1 0 3 3 3 1 zinc-RING finger domain K-box PF01486.17 PVD36798.1 - 0.015 15.5 3.0 0.029 14.5 0.4 2.4 2 0 0 2 2 2 0 K-box region zf-rbx1 PF12678.7 PVD36798.1 - 0.035 14.4 5.8 0.035 14.4 5.8 3.3 3 1 0 3 3 3 0 RING-H2 zinc finger domain ArfGap PF01412.18 PVD36798.1 - 0.082 13.0 23.9 1.3 9.1 6.6 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-HIT PF04438.16 PVD36798.1 - 0.091 12.6 9.3 0.19 11.7 5.3 3.0 2 0 0 2 2 2 0 HIT zinc finger Sec20 PF03908.13 PVD36798.1 - 0.099 12.6 1.4 0.29 11.1 0.8 2.2 2 0 0 2 2 2 0 Sec20 Baculo_PEP_C PF04513.12 PVD36798.1 - 0.91 9.6 5.0 1.3 9.1 0.1 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 PVD36798.1 - 1.1 8.6 3.2 1.3 8.2 1.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1690 PF07956.11 PVD36798.1 - 4.5 7.7 11.5 2.7 8.4 0.8 3.1 1 1 1 3 3 3 0 Protein of Unknown function (DUF1690) zf-B_box PF00643.24 PVD36799.1 - 7e-10 38.9 15.6 3.2e-06 27.2 3.8 4.4 4 1 1 5 5 5 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD36799.1 - 2.6e-09 36.8 7.5 2.6e-09 36.8 7.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36799.1 - 1.3e-07 31.4 10.7 1.3e-07 31.4 10.7 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36799.1 - 1.5e-07 31.6 8.7 1.5e-07 31.6 8.7 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36799.1 - 3.8e-07 29.8 8.7 3.8e-07 29.8 8.7 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36799.1 - 6.9e-07 29.0 11.6 6.9e-07 29.0 11.6 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD36799.1 - 1.8e-05 24.8 8.9 1.8e-05 24.8 8.9 3.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PVD36799.1 - 2.3e-05 24.3 11.8 2.3e-05 24.3 11.8 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36799.1 - 0.00047 20.0 8.7 0.00047 20.0 8.7 3.7 3 1 0 3 3 2 1 zinc-RING finger domain AP-5_subunit_s1 PF15001.6 PVD36799.1 - 0.024 14.6 0.4 0.058 13.4 0.4 1.6 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 5_nucleotid PF05761.14 PVD36799.1 - 0.077 11.9 4.6 0.021 13.8 0.8 1.7 2 0 0 2 2 2 0 5' nucleotidase family ArfGap PF01412.18 PVD36799.1 - 0.12 12.4 25.2 0.29 11.2 2.3 3.3 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf DUF445 PF04286.12 PVD36799.1 - 0.22 11.3 8.3 0.31 10.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SRP54_N PF02881.19 PVD36799.1 - 0.72 10.1 6.6 0.34 11.1 3.1 2.3 2 1 0 2 2 2 0 SRP54-type protein, helical bundle domain zf-HIT PF04438.16 PVD36799.1 - 6.9 6.6 16.0 0.63 10.0 5.4 3.5 3 0 0 3 3 3 0 HIT zinc finger zf-C3HC4 PF00097.25 PVD36800.1 - 8.5e-10 38.3 7.4 8.5e-10 38.3 7.4 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36800.1 - 5.2e-08 32.6 9.9 5.2e-08 32.6 9.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36800.1 - 1.4e-07 31.7 8.9 1.4e-07 31.7 8.9 3.7 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD36800.1 - 3e-07 30.2 11.2 3e-07 30.2 11.2 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36800.1 - 1e-06 28.5 9.3 1e-06 28.5 9.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36800.1 - 4.7e-06 26.5 12.2 4.7e-06 26.5 12.2 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36800.1 - 4.9e-06 26.6 20.3 1.4e-05 25.1 7.8 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD36800.1 - 1.9e-05 24.7 32.2 0.002 18.2 3.7 4.2 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD36800.1 - 0.0023 17.9 10.1 0.0023 17.9 10.1 4.0 3 1 0 3 3 2 1 zinc-RING finger domain HisKA_3 PF07730.13 PVD36800.1 - 0.041 14.4 0.4 0.16 12.5 0.2 2.1 2 0 0 2 2 1 0 Histidine kinase COG2 PF06148.11 PVD36800.1 - 0.13 12.3 5.4 5 7.2 2.7 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 PVD36800.1 - 0.15 12.6 2.1 2.8 8.6 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ArfGap PF01412.18 PVD36800.1 - 0.19 11.8 28.0 0.41 10.7 6.6 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf DUF445 PF04286.12 PVD36800.1 - 0.23 11.2 1.8 0.26 11.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RNA_pol_L_2 PF13656.6 PVD36800.1 - 0.31 10.8 1.8 1.6 8.6 0.4 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Fzo_mitofusin PF04799.13 PVD36800.1 - 0.32 10.5 5.5 5.9 6.4 0.9 2.5 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 PVD36800.1 - 0.37 10.8 9.6 4.4 7.4 5.4 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD36800.1 - 0.48 10.5 4.5 2.7 8.0 4.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-B_box PF00643.24 PVD36801.1 - 9.4e-09 35.3 16.6 3.5e-06 27.1 4.5 4.1 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 PVD36801.1 - 4.7e-08 32.8 9.0 4.7e-08 32.8 9.0 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36801.1 - 7.3e-08 32.2 6.7 7.3e-08 32.2 6.7 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36801.1 - 2.1e-06 27.5 10.4 2.1e-06 27.5 10.4 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD36801.1 - 3.5e-06 27.2 6.6 3.5e-06 27.2 6.6 3.9 4 0 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PVD36801.1 - 4.3e-06 26.7 8.3 4.3e-06 26.7 8.3 3.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36801.1 - 0.00015 21.7 9.8 0.00015 21.7 9.8 3.9 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD36801.1 - 0.00047 20.3 9.2 0.00047 20.3 9.2 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING DUF1351 PF07083.11 PVD36801.1 - 0.00056 19.7 3.9 0.016 14.9 2.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1351) FAM184 PF15665.5 PVD36801.1 - 0.0025 17.6 1.9 0.0048 16.7 1.9 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B CdvA PF18822.1 PVD36801.1 - 0.0075 16.1 2.8 2 8.2 0.4 2.7 3 0 0 3 3 3 2 CdvA-like coiled-coil domain DUF3584 PF12128.8 PVD36801.1 - 0.021 12.4 1.6 0.03 11.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 PVD36801.1 - 0.024 14.7 3.0 3.6 7.6 0.0 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 PVD36801.1 - 0.044 14.2 0.2 5.4 7.5 0.0 3.4 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BMFP PF04380.13 PVD36801.1 - 0.054 14.0 0.2 0.79 10.3 0.0 2.8 3 0 0 3 3 3 0 Membrane fusogenic activity SRA1 PF07304.11 PVD36801.1 - 0.058 13.2 2.9 0.067 13.0 0.3 2.4 3 0 0 3 3 2 0 Steroid receptor RNA activator (SRA1) Exonuc_VII_L PF02601.15 PVD36801.1 - 0.067 12.8 0.8 0.097 12.2 0.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO-like PF16789.5 PVD36801.1 - 0.16 12.0 3.4 0.24 11.4 2.7 1.6 1 1 0 1 1 1 0 YscO-like protein LMBR1 PF04791.16 PVD36801.1 - 0.32 9.8 1.6 0.4 9.5 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 PVD36801.1 - 0.34 10.9 7.1 0.89 9.6 3.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ArfGap PF01412.18 PVD36801.1 - 0.65 10.1 30.8 0.56 10.3 5.3 4.1 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf PIN_8 PF18476.1 PVD36801.1 - 0.81 9.5 3.7 1 9.2 3.0 1.5 1 1 0 1 1 1 0 PIN like domain I_LWEQ PF01608.17 PVD36801.1 - 1.3 9.2 6.9 1.9 8.7 4.0 2.3 1 1 1 2 2 2 0 I/LWEQ domain Seryl_tRNA_N PF02403.22 PVD36801.1 - 3.3 8.0 9.0 0.99 9.7 0.6 2.8 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain zf-B_box PF00643.24 PVD36802.1 - 5.2e-11 42.5 28.6 1.9e-06 27.9 3.5 4.0 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 PVD36802.1 - 1.3e-08 34.6 6.2 1.3e-08 34.6 6.2 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36802.1 - 3.2e-08 33.3 35.5 4e-08 33.0 8.4 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36802.1 - 3e-06 27.0 10.5 3e-06 27.0 10.5 3.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD36802.1 - 3.2e-06 27.0 7.3 3.2e-06 27.0 7.3 3.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD36802.1 - 4.7e-06 26.8 6.5 4.7e-06 26.8 6.5 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36802.1 - 7.4e-05 22.8 8.0 7.4e-05 22.8 8.0 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING AP1AR PF15745.5 PVD36802.1 - 0.00083 19.1 2.1 0.0012 18.5 2.1 1.2 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein zf-RING_5 PF14634.6 PVD36802.1 - 0.0012 18.8 9.3 0.0012 18.8 9.3 4.2 3 1 1 4 4 3 1 zinc-RING finger domain ArfGap PF01412.18 PVD36802.1 - 0.0019 18.2 27.5 0.065 13.3 6.1 3.5 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf DUF3584 PF12128.8 PVD36802.1 - 0.0059 14.2 1.5 0.0063 14.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CdvA PF18822.1 PVD36802.1 - 0.021 14.6 4.2 0.64 9.8 0.3 2.8 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Exonuc_VII_L PF02601.15 PVD36802.1 - 0.024 14.2 1.5 0.03 13.9 1.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GHL13 PF14883.6 PVD36802.1 - 0.027 13.6 2.1 2.4 7.1 0.3 2.1 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 13 OmpH PF03938.14 PVD36802.1 - 0.042 14.2 0.5 0.079 13.3 0.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PIN_8 PF18476.1 PVD36802.1 - 0.092 12.6 2.5 0.18 11.6 2.5 1.5 1 0 0 1 1 1 0 PIN like domain Apolipoprotein PF01442.18 PVD36802.1 - 0.11 12.4 2.9 0.22 11.3 2.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain I_LWEQ PF01608.17 PVD36802.1 - 0.11 12.7 6.0 0.17 12.1 4.1 2.2 1 1 1 2 2 2 0 I/LWEQ domain DUF1664 PF07889.12 PVD36802.1 - 0.16 12.0 6.1 1.6 8.8 1.5 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ArAE_1_C PF11728.8 PVD36802.1 - 0.18 11.8 2.5 0.12 12.4 0.7 1.6 2 0 0 2 2 1 0 Putative aromatic acid exporter C-terminal domain Cob_adeno_trans PF01923.18 PVD36802.1 - 0.22 11.6 1.9 0.66 10.1 0.4 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase LMBR1 PF04791.16 PVD36802.1 - 0.23 10.3 2.6 0.27 10.1 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein XhlA PF10779.9 PVD36802.1 - 0.24 11.6 3.1 0.87 9.8 0.2 2.8 2 1 1 3 3 3 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 PVD36802.1 - 0.31 11.1 1.6 4.6 7.3 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 PVD36802.1 - 0.41 10.7 3.5 1.9 8.5 0.3 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.11 PVD36802.1 - 0.63 10.1 4.0 2.2 8.4 0.9 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 PVD36802.1 - 0.7 9.9 4.8 10 6.1 1.1 2.7 2 0 0 2 2 2 0 Prefoldin subunit zf-C3HC4 PF00097.25 PVD36803.1 - 3.5e-10 39.6 6.6 3.5e-10 39.6 6.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36803.1 - 2.6e-08 34.0 7.8 2.6e-08 34.0 7.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36803.1 - 3.7e-08 33.1 9.9 3.7e-08 33.1 9.9 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36803.1 - 1.1e-07 31.6 10.4 1.1e-07 31.6 10.4 3.5 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD36803.1 - 1.1e-07 31.8 15.5 1.3e-05 25.2 3.7 4.2 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD36803.1 - 3.2e-07 30.1 8.1 3.2e-07 30.1 8.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36803.1 - 1.3e-06 28.3 11.2 1.3e-06 28.3 11.2 3.2 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36803.1 - 4.6e-06 26.7 7.5 4.6e-06 26.7 7.5 3.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING DUF4795 PF16043.5 PVD36803.1 - 0.00031 20.4 4.2 0.00057 19.6 4.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) zf-RING_5 PF14634.6 PVD36803.1 - 0.00079 19.3 9.2 0.00079 19.3 9.2 3.8 3 0 0 3 3 3 1 zinc-RING finger domain DUF3450 PF11932.8 PVD36803.1 - 0.0085 15.4 3.4 0.013 14.9 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF445 PF04286.12 PVD36803.1 - 0.037 13.8 0.9 0.056 13.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HBM PF16591.5 PVD36803.1 - 0.044 13.2 1.7 0.094 12.1 1.5 1.4 1 1 0 1 1 1 0 Helical bimodular sensor domain ApoLp-III PF07464.11 PVD36803.1 - 0.058 13.5 1.8 0.13 12.4 1.8 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF848 PF05852.11 PVD36803.1 - 0.12 12.5 3.9 0.091 12.9 1.5 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Relaxase PF03432.14 PVD36803.1 - 0.12 12.0 1.8 0.24 10.9 2.0 1.4 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain zf-HIT PF04438.16 PVD36803.1 - 0.12 12.3 8.6 0.23 11.4 4.6 2.9 2 0 0 2 2 2 0 HIT zinc finger PspA_IM30 PF04012.12 PVD36803.1 - 0.17 11.5 6.1 0.7 9.4 3.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family Exonuc_VII_L PF02601.15 PVD36803.1 - 0.18 11.4 1.7 0.23 11.0 1.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 PVD36803.1 - 0.29 11.4 4.3 14 6.0 0.2 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 PVD36803.1 - 0.32 9.8 1.1 0.36 9.7 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.13 PVD36803.1 - 0.41 10.7 6.5 1.5 8.9 3.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 PVD36803.1 - 0.46 10.5 8.1 1.2 9.1 5.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 PVD36803.1 - 0.48 10.2 3.9 0.8 9.5 3.9 1.3 1 0 0 1 1 1 0 PIN like domain CLZ PF16526.5 PVD36803.1 - 0.51 10.7 7.2 1.2 9.6 1.5 2.9 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2570 PF10828.8 PVD36803.1 - 0.59 10.0 4.2 1.1 9.1 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Phasin PF05597.11 PVD36803.1 - 0.68 10.0 4.6 0.97 9.4 3.3 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DLP_helical PF18709.1 PVD36803.1 - 0.88 8.7 4.9 1.2 8.2 0.7 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain Fez1 PF06818.15 PVD36803.1 - 1 9.8 7.7 2.6 8.5 7.6 1.7 1 1 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 PVD36803.1 - 1.3 9.0 4.8 25 4.9 1.0 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArfGap PF01412.18 PVD36803.1 - 1.4 9.0 26.4 0.044 13.9 5.3 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf COG2 PF06148.11 PVD36803.1 - 1.9 8.6 7.8 9.1 6.4 4.7 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.17 PVD36803.1 - 2.1 8.3 7.6 6.9 6.6 3.4 2.5 1 1 1 2 2 2 0 Prefoldin subunit Swi5 PF07061.11 PVD36803.1 - 2.6 8.2 6.2 0.79 9.9 0.5 2.6 3 0 0 3 3 2 0 Swi5 FlaC_arch PF05377.11 PVD36803.1 - 3.8 8.0 6.2 26 5.3 1.5 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 PVD36803.1 - 3.9 7.5 8.9 2.2 8.3 2.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit XhlA PF10779.9 PVD36803.1 - 4.8 7.5 6.6 3.6 7.9 2.0 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Med4 PF10018.9 PVD36803.1 - 5.9 6.5 8.4 9.2 5.9 6.4 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.12 PVD36803.1 - 9.5 6.8 10.2 3.6 8.1 1.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-C3HC4 PF00097.25 PVD36804.1 - 7.4e-10 38.5 7.6 7.4e-10 38.5 7.6 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36804.1 - 6.7e-08 32.3 10.4 6.7e-08 32.3 10.4 3.3 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36804.1 - 8.3e-08 32.4 8.9 8.3e-08 32.4 8.9 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36804.1 - 2.5e-07 30.4 8.9 2.5e-07 30.4 8.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36804.1 - 2.9e-07 30.2 11.5 2.9e-07 30.2 11.5 3.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD36804.1 - 1.1e-06 28.7 7.9 1.1e-06 28.7 7.9 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD36804.1 - 2.3e-06 27.7 19.6 4.7e-05 23.4 4.8 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 PVD36804.1 - 7.1e-06 26.0 12.5 7.1e-06 26.0 12.5 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD36804.1 - 0.0036 17.2 10.4 0.0036 17.2 10.4 4.3 3 2 1 4 4 2 1 zinc-RING finger domain DUF4795 PF16043.5 PVD36804.1 - 0.12 12.0 7.4 0.053 13.1 4.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) zf-HIT PF04438.16 PVD36804.1 - 0.42 10.5 9.0 0.5 10.3 4.7 2.9 2 0 0 2 2 2 0 HIT zinc finger CdvA PF18822.1 PVD36804.1 - 0.59 10.0 6.6 12 5.7 1.3 3.1 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 PVD36804.1 - 1 9.4 8.1 8.1 6.5 1.5 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ArfGap PF01412.18 PVD36804.1 - 1.8 8.6 28.6 0.12 12.5 5.9 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-C3HC4 PF00097.25 PVD36805.1 - 2.7e-10 39.9 6.1 2.7e-10 39.9 6.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36805.1 - 2.9e-09 36.6 36.7 6.8e-08 32.3 9.3 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36805.1 - 9.7e-09 35.1 6.5 9.7e-09 35.1 6.5 3.4 3 2 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD36805.1 - 3.9e-08 33.5 8.1 3.9e-08 33.5 8.1 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36805.1 - 1.2e-07 31.5 8.5 1.2e-07 31.5 8.5 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36805.1 - 1.9e-07 30.8 11.0 1.9e-07 30.8 11.0 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD36805.1 - 2.5e-06 27.5 17.8 0.00011 22.2 4.2 4.4 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36805.1 - 5.6e-06 26.4 7.9 5.6e-06 26.4 7.9 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PVD36805.1 - 0.0026 18.0 6.0 0.0026 18.0 6.0 3.9 4 0 0 4 4 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD36805.1 - 0.0032 17.4 10.0 0.0032 17.4 10.0 3.9 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 PVD36805.1 - 0.013 15.4 5.7 0.013 15.4 5.7 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein HisKA_3 PF07730.13 PVD36805.1 - 0.036 14.6 0.5 0.1 13.1 0.5 1.7 1 0 0 1 1 1 0 Histidine kinase K-box PF01486.17 PVD36805.1 - 0.05 13.8 0.7 0.05 13.8 0.7 1.9 2 0 0 2 2 2 0 K-box region DUF3450 PF11932.8 PVD36805.1 - 0.086 12.1 1.1 0.15 11.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CdvA PF18822.1 PVD36805.1 - 0.15 11.9 4.7 4 7.3 0.6 2.9 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Med4 PF10018.9 PVD36805.1 - 0.37 10.4 4.7 0.88 9.2 4.7 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1640 PF07798.11 PVD36805.1 - 2.4 8.2 9.5 2.9 7.9 6.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.11 PVD36805.1 - 4.3 7.9 5.9 1.7 9.3 0.7 2.7 3 1 0 3 3 2 0 Syntaxin 6, N-terminal zf-C3HC4 PF00097.25 PVD36806.1 - 2.3e-10 40.2 7.8 2.3e-10 40.2 7.8 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36806.1 - 2.3e-08 34.2 8.5 2.3e-08 34.2 8.5 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36806.1 - 3.3e-08 33.2 9.7 3.3e-08 33.2 9.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36806.1 - 1.8e-07 30.9 10.6 1.8e-07 30.9 10.6 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD36806.1 - 2.3e-07 30.7 8.0 2.3e-07 30.7 8.0 3.1 4 1 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36806.1 - 1e-06 28.4 8.4 1e-06 28.4 8.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36806.1 - 1.8e-06 28.0 15.9 5.2e-05 23.3 4.5 4.1 5 0 0 5 5 3 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36806.1 - 1.2e-05 25.3 8.5 1.2e-05 25.3 8.5 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36806.1 - 0.013 15.4 9.8 0.013 15.4 9.8 4.5 3 2 2 5 5 4 0 zinc-RING finger domain ArfGap PF01412.18 PVD36806.1 - 0.1 12.7 27.8 0.093 12.8 5.7 3.7 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf PIN_8 PF18476.1 PVD36806.1 - 0.17 11.7 2.0 0.28 11.0 2.0 1.3 1 0 0 1 1 1 0 PIN like domain DUF1664 PF07889.12 PVD36806.1 - 0.19 11.8 9.6 4 7.5 5.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1465 PF07323.12 PVD36806.1 - 0.2 11.5 1.4 15 5.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) NPV_P10 PF05531.12 PVD36806.1 - 0.36 11.3 3.4 5.6 7.5 0.3 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CdvA PF18822.1 PVD36806.1 - 0.41 10.5 5.2 8.9 6.2 0.1 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain zf-HIT PF04438.16 PVD36806.1 - 0.45 10.4 10.4 0.89 9.5 6.2 2.9 2 0 0 2 2 2 0 HIT zinc finger XhlA PF10779.9 PVD36806.1 - 0.48 10.7 3.1 0.52 10.6 0.9 2.2 1 1 1 2 2 2 0 Haemolysin XhlA COG2 PF06148.11 PVD36806.1 - 0.7 10.0 5.3 15 5.6 1.8 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med4 PF10018.9 PVD36806.1 - 4.2 7.0 9.6 9.3 5.9 0.8 3.1 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-C3HC4 PF00097.25 PVD36807.1 - 4.3e-10 39.3 6.6 4.3e-10 39.3 6.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36807.1 - 3.3e-08 33.7 7.8 3.3e-08 33.7 7.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36807.1 - 4.6e-08 32.8 9.9 4.6e-08 32.8 9.9 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36807.1 - 1.4e-07 31.3 10.4 1.4e-07 31.3 10.4 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36807.1 - 4e-07 29.8 8.1 4e-07 29.8 8.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36807.1 - 1.6e-06 28.0 11.2 1.6e-06 28.0 11.2 3.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-B_box PF00643.24 PVD36807.1 - 2.6e-06 27.5 16.8 0.00022 21.3 5.0 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36807.1 - 5.7e-06 26.4 7.5 5.7e-06 26.4 7.5 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36807.1 - 0.00098 19.0 9.2 0.00098 19.0 9.2 4.1 3 1 0 3 3 2 1 zinc-RING finger domain Neuralized PF07177.12 PVD36807.1 - 0.03 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Neuralized DUF1664 PF07889.12 PVD36807.1 - 0.057 13.5 8.9 3.3 7.8 4.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ArfGap PF01412.18 PVD36807.1 - 0.31 11.1 25.8 0.29 11.2 4.6 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-HIT PF04438.16 PVD36807.1 - 3.3 7.7 13.6 0.74 9.7 6.1 3.3 3 0 0 3 3 3 0 HIT zinc finger zf-C3HC4 PF00097.25 PVD36808.1 - 1.1e-10 41.2 7.0 1.1e-10 41.2 7.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36808.1 - 8e-09 35.7 7.7 8e-09 35.7 7.7 3.4 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD36808.1 - 2.2e-08 33.8 8.0 2.2e-08 33.8 8.0 3.7 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PVD36808.1 - 2.9e-08 33.4 10.1 2.9e-08 33.4 10.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36808.1 - 3.3e-08 33.6 14.4 8.8e-06 25.8 3.5 4.1 5 0 0 5 5 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD36808.1 - 1.2e-07 31.4 8.0 1.2e-07 31.4 8.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36808.1 - 2.3e-06 27.5 11.0 2.3e-06 27.5 11.0 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36808.1 - 1.2e-05 25.3 7.6 1.2e-05 25.3 7.6 2.8 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36808.1 - 0.00094 19.1 9.5 0.00094 19.1 9.5 3.8 3 1 0 3 3 2 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 PVD36808.1 - 0.012 15.7 1.2 0.012 15.7 1.2 3.3 3 1 1 4 4 4 0 Transposase zinc-binding domain DUF1664 PF07889.12 PVD36808.1 - 0.034 14.2 6.6 6.5 6.8 4.6 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 PVD36808.1 - 0.24 11.3 10.1 0.42 10.5 5.9 2.8 2 0 0 2 2 2 0 HIT zinc finger Prefoldin PF02996.17 PVD36808.1 - 0.64 10.0 4.1 0.99 9.3 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit CdvA PF18822.1 PVD36808.1 - 0.76 9.6 4.3 8.2 6.3 0.1 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain ArfGap PF01412.18 PVD36808.1 - 8.2 6.5 26.0 0.56 10.3 4.9 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-C3HC4 PF00097.25 PVD36809.1 - 6.9e-11 41.8 6.4 6.9e-11 41.8 6.4 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36809.1 - 1.2e-09 38.3 7.9 1.2e-09 38.3 7.9 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36809.1 - 8.8e-09 35.1 7.8 8.8e-09 35.1 7.8 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36809.1 - 2.4e-08 33.7 9.4 2.4e-08 33.7 9.4 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36809.1 - 6.2e-08 32.4 10.2 6.2e-08 32.4 10.2 3.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD36809.1 - 8.2e-08 32.1 11.2 8.2e-08 32.1 11.2 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36809.1 - 7.8e-07 29.1 7.6 7.8e-07 29.1 7.6 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PVD36809.1 - 1.8e-06 28.0 18.6 7e-05 22.9 4.6 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD36809.1 - 0.00018 21.4 9.3 0.00018 21.4 9.3 3.9 3 1 0 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PVD36809.1 - 0.0036 17.6 6.3 0.0036 17.6 6.3 3.9 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PVD36809.1 - 0.0082 15.9 4.1 0.0082 15.9 4.1 3.6 3 1 0 3 3 3 1 RING-like zinc finger EzrA PF06160.12 PVD36809.1 - 0.026 12.7 0.2 0.036 12.3 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4795 PF16043.5 PVD36809.1 - 0.08 12.5 6.3 0.24 11.0 6.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 PVD36809.1 - 0.094 12.8 6.8 1 9.4 5.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 PVD36809.1 - 0.1 12.4 1.3 0.16 11.8 1.3 1.3 1 0 0 1 1 1 0 PIN like domain TPR_MLP1_2 PF07926.12 PVD36809.1 - 0.25 11.4 3.3 0.55 10.3 3.3 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 PVD36809.1 - 0.42 10.1 5.9 2.8 7.5 1.2 2.3 1 1 1 2 2 2 0 fzo-like conserved region zf-C3HC4 PF00097.25 PVD36810.1 - 7e-10 38.6 7.9 7e-10 38.6 7.9 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36810.1 - 4.4e-08 33.1 16.3 2.4e-05 24.4 3.7 4.7 3 1 1 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD36810.1 - 5.6e-08 33.0 8.8 5.6e-08 33.0 8.8 3.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36810.1 - 1.2e-07 31.4 11.2 1.2e-07 31.4 11.2 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36810.1 - 3.5e-07 30.0 10.5 3.5e-07 30.0 10.5 3.9 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36810.1 - 5.1e-07 29.4 9.2 5.1e-07 29.4 9.2 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36810.1 - 1.4e-06 28.2 11.5 1.4e-06 28.2 11.5 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36810.1 - 4e-06 26.9 8.5 4e-06 26.9 8.5 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36810.1 - 0.00017 21.5 10.3 0.00017 21.5 10.3 4.1 3 1 0 3 3 2 1 zinc-RING finger domain SRA1 PF07304.11 PVD36810.1 - 0.015 15.0 1.4 0.054 13.3 1.4 2.0 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF1351 PF07083.11 PVD36810.1 - 0.024 14.4 2.0 0.037 13.8 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) DUF3829 PF12889.7 PVD36810.1 - 0.08 12.4 3.2 0.43 10.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) HisKA_3 PF07730.13 PVD36810.1 - 0.098 13.2 0.3 0.29 11.7 0.3 1.8 1 0 0 1 1 1 0 Histidine kinase FAA_hydro_N_2 PF18288.1 PVD36810.1 - 0.15 12.5 0.6 2 8.9 0.3 2.5 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Baculo_PEP_C PF04513.12 PVD36810.1 - 0.31 11.1 4.6 2.2 8.3 0.8 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 PVD36810.1 - 0.48 9.9 6.7 5.1 6.6 1.4 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 PVD36810.1 - 0.49 10.4 9.4 8.7 6.4 7.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD36810.1 - 0.92 9.6 5.0 4.1 7.5 5.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.13 PVD36810.1 - 0.93 10.1 3.0 1.1 9.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) COG2 PF06148.11 PVD36810.1 - 1.1 9.3 7.0 2.3 8.3 0.5 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C3HC4 PF00097.25 PVD36811.1 - 2.6e-09 36.8 6.3 2.6e-09 36.8 6.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36811.1 - 2.6e-08 33.6 7.4 2.6e-08 33.6 7.4 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36811.1 - 8.1e-08 32.0 10.6 8.1e-08 32.0 10.6 3.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD36811.1 - 2.9e-07 30.5 19.2 4.7e-05 23.5 5.7 4.1 5 0 0 5 5 3 2 B-box zinc finger zf-RING_2 PF13639.6 PVD36811.1 - 3.9e-07 30.3 7.5 3.9e-07 30.3 7.5 3.9 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36811.1 - 8.7e-07 28.7 6.9 8.7e-07 28.7 6.9 3.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36811.1 - 2.5e-06 27.4 11.4 2.5e-06 27.4 11.4 3.4 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36811.1 - 0.00017 21.7 8.2 0.00017 21.7 8.2 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36811.1 - 0.0011 18.9 9.7 0.0011 18.9 9.7 4.5 3 1 0 3 3 2 1 zinc-RING finger domain HMMR_N PF15905.5 PVD36811.1 - 0.012 15.1 1.9 0.012 15.1 1.9 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Activator-TraM PF11657.8 PVD36811.1 - 0.017 15.0 0.6 0.035 13.9 0.6 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Syntaxin-6_N PF09177.11 PVD36811.1 - 0.024 15.2 1.7 0.046 14.3 0.6 2.0 3 0 0 3 3 1 0 Syntaxin 6, N-terminal DUF2130 PF09903.9 PVD36811.1 - 0.025 13.9 1.6 0.038 13.3 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Med9 PF07544.13 PVD36811.1 - 0.039 14.0 2.7 0.056 13.5 1.6 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SPATA24 PF15175.6 PVD36811.1 - 0.039 13.8 7.5 0.1 12.5 5.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Filament PF00038.21 PVD36811.1 - 0.048 13.2 2.7 0.077 12.6 2.7 1.4 1 1 0 1 1 1 0 Intermediate filament protein Telomere_reg-2 PF10193.9 PVD36811.1 - 0.074 13.5 0.9 1.9 9.0 0.4 2.5 1 1 1 2 2 2 0 Telomere length regulation protein AATF-Che1 PF13339.6 PVD36811.1 - 0.076 13.7 1.5 0.73 10.5 1.1 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Med2 PF11214.8 PVD36811.1 - 0.084 13.0 2.7 2.7 8.2 0.1 2.7 1 1 1 2 2 2 0 Mediator complex subunit 2 DUF445 PF04286.12 PVD36811.1 - 0.088 12.6 0.5 0.15 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 PVD36811.1 - 0.13 12.3 5.0 0.5 10.4 2.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_I PF06008.14 PVD36811.1 - 0.14 11.8 3.1 4.3 7.0 0.0 2.4 1 1 1 2 2 2 0 Laminin Domain I ApoLp-III PF07464.11 PVD36811.1 - 0.15 12.2 3.7 0.19 11.8 1.7 2.1 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) NYD-SP28 PF14772.6 PVD36811.1 - 0.17 11.9 7.3 3.3 7.8 0.2 3.2 2 1 1 3 3 3 0 Sperm tail DUF4795 PF16043.5 PVD36811.1 - 0.25 10.9 7.3 0.34 10.5 5.8 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 PVD36811.1 - 0.48 10.3 2.8 1.2 8.9 2.8 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain UPF0449 PF15136.6 PVD36811.1 - 0.62 10.6 3.4 1.4 9.5 0.4 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Prefoldin PF02996.17 PVD36811.1 - 1.5 8.7 6.7 4.1 7.4 0.1 3.0 2 1 1 3 3 3 0 Prefoldin subunit Prefoldin_2 PF01920.20 PVD36811.1 - 4.1 7.4 7.4 12 5.9 5.4 2.6 2 1 0 2 2 2 0 Prefoldin subunit SRA1 PF07304.11 PVD36811.1 - 6.4 6.5 8.0 1 9.1 0.2 3.0 3 1 0 3 3 3 0 Steroid receptor RNA activator (SRA1) zf-C3HC4 PF00097.25 PVD36812.1 - 2.1e-10 40.3 6.7 2.1e-10 40.3 6.7 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36812.1 - 1.3e-09 37.8 37.1 7e-09 35.4 10.1 3.5 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36812.1 - 3.8e-09 36.7 8.2 3.8e-09 36.7 8.2 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PVD36812.1 - 2.6e-08 33.6 8.6 2.6e-08 33.6 8.6 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36812.1 - 2.6e-08 33.8 11.7 2.6e-08 33.8 11.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD36812.1 - 2.9e-07 30.5 8.3 2.9e-07 30.5 8.3 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36812.1 - 6.1e-07 29.2 10.3 6.1e-07 29.2 10.3 3.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD36812.1 - 9.7e-07 28.8 18.9 1.3e-05 25.3 5.1 4.1 4 1 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 PVD36812.1 - 8e-05 22.5 8.5 8e-05 22.5 8.5 3.9 3 1 0 3 3 3 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 PVD36812.1 - 0.016 15.2 1.4 0.016 15.2 1.4 3.8 4 1 0 4 4 4 0 Transposase zinc-binding domain DUF3450 PF11932.8 PVD36812.1 - 0.07 12.4 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 PVD36812.1 - 0.098 12.7 4.3 1 9.4 1.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF515 PF04415.12 PVD36812.1 - 0.37 9.1 2.7 0.28 9.5 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Prefoldin_2 PF01920.20 PVD36812.1 - 0.4 10.7 2.7 1.9 8.5 2.4 2.1 1 1 0 1 1 1 0 Prefoldin subunit COG2 PF06148.11 PVD36812.1 - 0.62 10.2 2.8 12 6.0 1.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CdvA PF18822.1 PVD36812.1 - 2.1 8.2 4.3 3.4 7.5 0.3 2.5 2 1 1 3 3 3 0 CdvA-like coiled-coil domain zf-C3HC4 PF00097.25 PVD36814.1 - 3.9e-10 39.4 6.5 3.9e-10 39.4 6.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36814.1 - 1.2e-08 34.9 35.6 3.2e-06 27.2 6.1 4.3 4 0 0 4 4 3 2 B-box zinc finger Prok-RING_4 PF14447.6 PVD36814.1 - 4e-08 33.0 11.7 4e-08 33.0 11.7 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD36814.1 - 1.6e-07 31.2 7.5 1.6e-07 31.2 7.5 3.4 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36814.1 - 2.6e-07 30.4 35.2 3e-07 30.2 9.1 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD36814.1 - 2.7e-07 30.3 7.1 2.7e-07 30.3 7.1 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36814.1 - 8.6e-07 29.2 7.6 8.6e-07 29.2 7.6 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 PVD36814.1 - 7.2e-05 22.9 8.7 7.2e-05 22.9 8.7 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36814.1 - 0.0013 18.7 9.7 0.0013 18.7 9.7 4.5 3 1 1 4 4 3 1 zinc-RING finger domain Peptidase_M16_C PF05193.21 PVD36814.1 - 0.012 15.6 0.7 0.77 9.7 0.0 2.6 2 1 1 3 3 3 0 Peptidase M16 inactive domain CdvA PF18822.1 PVD36814.1 - 0.021 14.6 4.8 2.3 8.1 0.6 3.2 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Med9 PF07544.13 PVD36814.1 - 0.04 14.0 3.4 0.094 12.8 3.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Filament PF00038.21 PVD36814.1 - 0.057 13.0 3.7 0.063 12.8 2.7 1.4 1 1 0 1 1 1 0 Intermediate filament protein Apolipoprotein PF01442.18 PVD36814.1 - 0.065 13.1 3.6 0.21 11.4 3.5 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 PVD36814.1 - 0.067 12.8 8.9 0.058 13.0 7.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Med2 PF11214.8 PVD36814.1 - 0.076 13.2 3.8 1.4 9.1 0.1 2.5 1 1 1 2 2 2 0 Mediator complex subunit 2 Syntaxin-6_N PF09177.11 PVD36814.1 - 0.077 13.6 3.3 0.13 12.8 0.5 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 PVD36814.1 - 0.1 12.2 1.0 0.15 11.6 1.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 PVD36814.1 - 0.21 11.5 7.0 1.1 9.2 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 PVD36814.1 - 0.28 11.2 7.0 5.3 7.1 1.6 3.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 PVD36814.1 - 0.42 10.7 5.9 0.21 11.7 3.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 PVD36814.1 - 0.47 10.2 5.1 0.28 10.9 0.5 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain ApoLp-III PF07464.11 PVD36814.1 - 0.57 10.3 5.3 0.78 9.8 3.4 2.0 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) PIN_8 PF18476.1 PVD36814.1 - 0.63 9.8 3.8 1 9.1 3.2 1.6 1 1 0 1 1 1 0 PIN like domain DUF3450 PF11932.8 PVD36814.1 - 0.65 9.3 3.1 0.7 9.2 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 PVD36814.1 - 0.79 8.6 6.2 1.6 7.5 6.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-HIT PF04438.16 PVD36814.1 - 0.85 9.6 12.6 0.4 10.6 6.6 2.9 2 0 0 2 2 2 0 HIT zinc finger NYD-SP28 PF14772.6 PVD36814.1 - 0.99 9.5 7.9 6.7 6.8 0.2 3.3 2 1 1 3 3 3 0 Sperm tail SRA1 PF07304.11 PVD36814.1 - 1.7 8.4 8.8 0.23 11.2 0.9 3.1 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Prefoldin_2 PF01920.20 PVD36814.1 - 2 8.4 8.4 3.6 7.6 6.7 2.3 2 1 0 2 2 2 0 Prefoldin subunit ArfGap PF01412.18 PVD36814.1 - 4.7 7.3 27.8 0.03 14.4 5.2 3.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf ADIP PF11559.8 PVD36814.1 - 6.5 6.8 9.4 3.3 7.8 3.3 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding zf-C3HC4 PF00097.25 PVD36815.1 - 3.7e-10 39.5 7.4 3.7e-10 39.5 7.4 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36815.1 - 1.1e-08 35.0 5.4 1.1e-08 35.0 5.4 3.7 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD36815.1 - 3.8e-08 33.0 10.3 3.8e-08 33.0 10.3 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36815.1 - 3.9e-08 33.3 16.7 2.1e-05 24.5 5.0 4.2 3 1 1 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 PVD36815.1 - 4.1e-08 33.4 8.2 4.1e-08 33.4 8.2 3.8 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 PVD36815.1 - 1.4e-07 31.3 10.7 1.4e-07 31.3 10.7 3.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36815.1 - 3.5e-07 30.0 8.7 3.5e-07 30.0 8.7 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36815.1 - 2.3e-06 27.6 8.1 2.3e-06 27.6 8.1 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36815.1 - 0.00017 21.5 9.6 0.00017 21.5 9.6 3.9 3 1 0 3 3 3 1 zinc-RING finger domain Syntaxin-6_N PF09177.11 PVD36815.1 - 0.0044 17.5 0.8 0.0044 17.5 0.8 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF1664 PF07889.12 PVD36815.1 - 0.02 14.9 12.4 2 8.5 7.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 PVD36815.1 - 0.026 13.8 2.6 0.042 13.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-HIT PF04438.16 PVD36815.1 - 0.028 14.3 7.8 0.068 13.1 4.1 3.0 2 0 0 2 2 2 0 HIT zinc finger HBM PF16591.5 PVD36815.1 - 0.078 12.4 1.3 0.098 12.1 0.5 1.6 2 0 0 2 2 2 0 Helical bimodular sensor domain TPR_MLP1_2 PF07926.12 PVD36815.1 - 0.08 13.0 4.7 0.15 12.2 4.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 PVD36815.1 - 0.082 13.1 5.3 1.5 9.1 0.4 3.0 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 PVD36815.1 - 0.091 11.7 1.5 0.11 11.4 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4795 PF16043.5 PVD36815.1 - 0.15 11.7 11.5 0.23 11.0 10.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Cor1 PF04803.12 PVD36815.1 - 0.17 12.1 6.8 0.42 10.8 6.8 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region COG5 PF10392.9 PVD36815.1 - 0.18 12.0 3.8 2.6 8.2 1.7 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF883 PF05957.13 PVD36815.1 - 0.63 10.7 3.6 23 5.7 0.3 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Prefoldin PF02996.17 PVD36815.1 - 1.1 9.1 7.6 2.2 8.2 1.1 2.7 1 1 1 2 2 2 0 Prefoldin subunit Mod_r PF07200.13 PVD36815.1 - 1.4 9.0 7.6 4.5 7.4 2.6 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 PVD36815.1 - 1.5 9.0 10.8 0.66 10.1 8.2 1.8 2 0 0 2 2 1 0 Tropomyosin like Fez1 PF06818.15 PVD36815.1 - 1.6 9.1 10.1 0.48 10.9 5.4 2.1 1 1 1 2 2 2 0 Fez1 K-box PF01486.17 PVD36815.1 - 1.6 8.9 7.9 0.87 9.8 2.9 2.5 1 1 0 2 2 2 0 K-box region DUF948 PF06103.11 PVD36815.1 - 2.1 8.6 6.7 4.8 7.5 0.6 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) ArfGap PF01412.18 PVD36815.1 - 3 7.9 28.1 1.4 9.0 5.9 3.6 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf TMF_DNA_bd PF12329.8 PVD36815.1 - 3.3 7.8 7.6 2.4 8.2 0.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RNA_pol_L_2 PF13656.6 PVD36815.1 - 3.3 7.5 5.7 1.8 8.4 0.4 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C3HC4 PF00097.25 PVD36816.1 - 2.3e-11 43.3 5.5 2.3e-11 43.3 5.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36816.1 - 7.7e-10 39.0 7.6 7.7e-10 39.0 7.6 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36816.1 - 7.7e-10 38.5 36.2 1e-08 34.9 8.8 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD36816.1 - 3.7e-09 36.3 7.7 3.7e-09 36.3 7.7 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36816.1 - 4.4e-09 36.2 7.0 4.4e-09 36.2 7.0 3.5 3 2 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PVD36816.1 - 1.5e-08 34.3 9.9 1.5e-08 34.3 9.9 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 PVD36816.1 - 5.4e-08 32.9 17.1 1.6e-05 24.9 4.0 4.4 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36816.1 - 2.9e-06 27.3 7.4 2.9e-06 27.3 7.4 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PVD36816.1 - 0.00015 22.0 5.4 0.00015 22.0 5.4 3.9 4 0 0 4 4 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PVD36816.1 - 0.00039 20.3 9.2 0.00039 20.3 9.2 3.8 3 1 1 4 4 4 1 zinc-RING finger domain DUF3450 PF11932.8 PVD36816.1 - 0.0085 15.4 1.9 0.012 14.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HisKA_3 PF07730.13 PVD36816.1 - 0.077 13.5 0.6 0.17 12.4 0.6 1.5 1 0 0 1 1 1 0 Histidine kinase K-box PF01486.17 PVD36816.1 - 0.23 11.6 5.8 0.14 12.3 2.6 2.0 1 1 1 2 2 2 0 K-box region DUF1664 PF07889.12 PVD36816.1 - 0.53 10.3 6.5 12 5.9 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.25 PVD36817.1 - 1.7e-10 40.6 7.1 1.7e-10 40.6 7.1 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36817.1 - 9.4e-09 35.5 7.5 9.4e-09 35.5 7.5 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36817.1 - 2e-08 33.9 9.9 2e-08 33.9 9.9 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36817.1 - 5.6e-08 32.5 10.4 5.6e-08 32.5 10.4 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD36817.1 - 1.8e-07 30.9 7.8 1.8e-07 30.9 7.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36817.1 - 5.3e-07 29.6 10.2 5.3e-07 29.6 10.2 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-B_box PF00643.24 PVD36817.1 - 2e-06 27.9 20.4 1.3e-05 25.3 5.0 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 PVD36817.1 - 1.3e-05 25.2 7.6 1.3e-05 25.2 7.6 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36817.1 - 0.00036 20.4 9.0 0.00036 20.4 9.0 4.1 3 2 0 3 3 1 1 zinc-RING finger domain SRA1 PF07304.11 PVD36817.1 - 0.025 14.3 1.0 0.025 14.3 1.0 3.1 3 1 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Apolipoprotein PF01442.18 PVD36817.1 - 0.22 11.4 6.0 0.36 10.7 6.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin PF02996.17 PVD36817.1 - 0.33 10.9 6.0 0.55 10.1 1.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit LMBR1 PF04791.16 PVD36817.1 - 0.43 9.4 1.8 0.56 9.1 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 PVD36817.1 - 0.49 10.4 9.5 6.4 6.8 5.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 PVD36817.1 - 0.52 10.4 6.5 3.2 7.8 3.1 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 PVD36817.1 - 2.5 8.5 7.4 5.6 7.4 1.2 2.7 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ArfGap PF01412.18 PVD36817.1 - 5.1 7.2 28.9 0.32 11.1 6.0 3.5 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf zf-C3HC4 PF00097.25 PVD36818.1 - 1.4e-10 40.9 7.3 1.4e-10 40.9 7.3 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD36818.1 - 5.1e-09 36.0 8.8 5.1e-09 36.0 8.8 3.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD36818.1 - 7.8e-09 35.7 8.6 7.8e-09 35.7 8.6 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD36818.1 - 2.2e-08 33.8 9.5 2.2e-08 33.8 9.5 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD36818.1 - 4.1e-08 33.3 17.2 4.8e-05 23.4 5.3 4.0 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 PVD36818.1 - 7.1e-08 32.2 8.8 7.1e-08 32.2 8.8 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD36818.1 - 8.9e-08 32.2 8.4 8.9e-08 32.2 8.4 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD36818.1 - 2.2e-07 30.6 10.0 2.2e-07 30.6 10.0 3.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD36818.1 - 0.00026 20.9 8.9 0.00026 20.9 8.9 4.3 3 2 1 4 4 2 1 zinc-RING finger domain HMMR_N PF15905.5 PVD36818.1 - 0.0011 18.5 3.8 0.0016 18.0 3.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal SRA1 PF07304.11 PVD36818.1 - 0.017 14.9 3.7 0.48 10.2 2.6 2.7 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) MukF_M PF17192.4 PVD36818.1 - 0.038 13.7 1.9 0.073 12.8 1.9 1.5 1 0 0 1 1 1 0 MukF middle domain DUF3450 PF11932.8 PVD36818.1 - 0.045 13.0 2.5 0.064 12.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rad50_zn_hook PF04423.14 PVD36818.1 - 0.048 13.5 5.0 0.16 11.8 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF1465 PF07323.12 PVD36818.1 - 0.076 12.9 1.5 3.2 7.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Cdd1 PF11731.8 PVD36818.1 - 0.077 13.2 0.2 0.19 12.0 0.2 1.7 1 0 0 1 1 1 0 Pathogenicity locus Sas10_Utp3 PF04000.15 PVD36818.1 - 0.12 13.0 2.5 15 6.3 0.0 3.3 3 0 0 3 3 3 0 Sas10/Utp3/C1D family HisKA_3 PF07730.13 PVD36818.1 - 0.13 12.8 1.7 0.47 11.0 0.4 2.3 2 0 0 2 2 2 0 Histidine kinase TssC PF17541.2 PVD36818.1 - 0.15 10.9 2.7 0.21 10.4 2.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB UPF0449 PF15136.6 PVD36818.1 - 0.16 12.4 2.5 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 DLP_helical PF18709.1 PVD36818.1 - 0.23 10.6 4.1 0.81 8.8 0.8 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain TPR_MLP1_2 PF07926.12 PVD36818.1 - 0.44 10.6 5.5 1.2 9.2 4.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.17 PVD36818.1 - 0.91 9.5 5.9 4.8 7.1 0.7 2.4 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 PVD36818.1 - 0.99 9.5 7.4 4 7.5 5.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YtxH PF12732.7 PVD36818.1 - 1.5 9.4 3.5 57 4.3 3.5 2.5 1 1 0 1 1 1 0 YtxH-like protein FlaC_arch PF05377.11 PVD36818.1 - 5.8 7.4 7.5 21 5.6 1.1 2.9 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Voltage_CLC PF00654.20 PVD36819.1 - 1.1e-59 202.5 18.8 2.1e-59 201.6 18.8 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel TAT_signal PF10518.9 PVD36819.1 - 0.081 12.8 5.5 0.31 11.0 5.5 2.1 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence CBS PF00571.28 PVD36821.1 - 3.1e-06 27.5 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 CBS domain PhyH PF05721.13 PVD36822.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.22 PVD36823.1 - 2.7e-108 362.7 0.0 3.2e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lectin_C PF00059.21 PVD36824.1 - 1.5e-20 73.9 0.2 1e-10 42.3 0.0 2.7 3 0 0 3 3 3 2 Lectin C-type domain Peptidase_M13_N PF05649.13 PVD36825.1 - 1.8e-96 324.1 0.0 2.6e-96 323.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36825.1 - 1.2e-48 165.4 0.1 5.3e-36 124.2 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M13 COR PF16095.5 PVD36826.1 - 5.3e-42 143.8 0.1 3.6e-40 137.9 0.0 2.5 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 PVD36826.1 - 5.6e-23 81.4 0.0 1.4e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MBT PF02820.18 PVD36826.1 - 7.3e-20 71.1 0.0 1.9e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 mbt repeat TIR_2 PF13676.6 PVD36826.1 - 3e-17 63.3 0.0 8.1e-10 39.3 0.0 3.2 2 0 0 2 2 2 2 TIR domain Ras PF00071.22 PVD36826.1 - 4.1e-13 49.2 0.0 9.6e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.7 PVD36826.1 - 1.4e-10 41.3 26.5 9.4e-05 22.7 1.8 6.2 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD36826.1 - 4.3e-10 39.2 24.4 0.00077 19.2 2.2 5.7 4 1 1 5 5 5 4 Leucine rich repeat Arf PF00025.21 PVD36826.1 - 0.011 15.1 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PVD36826.1 - 0.028 14.3 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase TIR PF01582.20 PVD36826.1 - 0.12 12.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 TIR domain MMR_HSR1 PF01926.23 PVD36826.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_9 PF14580.6 PVD36826.1 - 0.25 10.8 11.9 0.75 9.3 0.2 3.2 2 1 1 3 3 3 0 Leucine-rich repeat Peptidase_M13 PF01431.21 PVD36827.1 - 4.9e-63 212.5 0.0 2.9e-61 206.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD36827.1 - 2.1e-23 83.6 0.1 2.9e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36828.1 - 5.6e-49 166.5 0.1 5.1e-29 101.3 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD36828.1 - 1.2e-09 38.3 1.0 1.8e-09 37.8 0.1 1.7 3 0 0 3 3 3 1 Peptidase family M13 SSF PF00474.17 PVD36829.1 - 9.2e-134 446.3 19.6 1.2e-133 445.9 19.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Toxin_2 PF00451.19 PVD36829.1 - 0.056 13.8 3.4 0.13 12.6 3.4 1.6 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Use1 PF09753.9 PVD36829.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 TH1 PF04858.13 PVD36829.1 - 0.19 10.3 0.2 0.3 9.7 0.2 1.3 1 0 0 1 1 1 0 TH1 protein bPH_2 PF03703.14 PVD36830.1 - 0.13 12.4 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain RNase_P_Rpp14 PF01900.19 PVD36832.1 - 7.6e-08 32.5 0.1 1.3e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 Rpp14/Pop5 family LuxT_C PF18285.1 PVD36832.1 - 0.0036 17.8 0.9 0.026 15.0 0.8 2.2 1 1 1 2 2 2 1 Tetracycline repressor LuxT C-terminal domain DUF384 PF04064.13 PVD36832.1 - 0.89 9.5 4.0 1.2 9.1 1.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF384) DUF3523 PF12037.8 PVD36833.1 - 2.6e-91 305.7 29.3 4.9e-91 304.8 29.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 PVD36833.1 - 8.4e-21 74.8 0.3 2.3e-20 73.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PVD36833.1 - 1.5e-05 25.4 0.1 1.5e-05 25.4 0.1 3.2 2 2 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 PVD36833.1 - 9.6e-05 22.2 0.0 0.00046 20.0 0.0 2.3 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PVD36833.1 - 0.0026 17.8 2.8 0.0051 16.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD36833.1 - 0.0041 17.4 7.6 0.048 13.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 PVD36833.1 - 0.0043 16.5 0.2 0.042 13.2 0.0 2.5 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 PVD36833.1 - 0.0052 17.3 3.8 0.0076 16.8 0.0 3.0 2 1 0 2 2 1 1 AAA domain NACHT PF05729.12 PVD36833.1 - 0.0066 16.4 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 PVD36833.1 - 0.0071 16.3 0.6 0.021 14.8 0.0 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 PVD36833.1 - 0.0078 15.9 0.0 0.0078 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 PVD36833.1 - 0.0082 16.3 0.0 0.0082 16.3 0.0 2.9 2 1 0 2 2 1 1 AAA domain TsaE PF02367.17 PVD36833.1 - 0.0086 16.1 1.6 0.037 14.0 0.0 2.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PVD36833.1 - 0.019 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 PVD36833.1 - 0.021 14.7 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PVD36833.1 - 0.033 13.7 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_lid_3 PF17862.1 PVD36833.1 - 0.047 13.5 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA+ lid domain AAA_25 PF13481.6 PVD36833.1 - 0.051 13.2 0.0 0.051 13.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 PVD36833.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 PVD36833.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PVD36833.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.7 2 2 1 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 PVD36833.1 - 2.5 7.8 5.0 0.95 9.2 0.1 2.5 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Fer2_3 PF13085.6 PVD36834.1 - 3.5e-35 120.3 0.0 5.6e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 PVD36834.1 - 3.2e-09 37.2 5.6 3.2e-09 37.2 5.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PVD36834.1 - 1.5e-07 31.8 21.8 1.4e-06 28.7 8.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 PVD36834.1 - 4.5e-07 29.9 2.7 4.5e-07 29.9 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 PVD36834.1 - 0.0015 18.6 4.4 0.0015 18.6 4.4 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 PVD36834.1 - 0.0075 16.2 0.4 0.0075 16.2 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 PVD36834.1 - 0.037 14.6 7.9 0.037 14.6 7.9 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 PVD36834.1 - 0.15 12.6 0.5 0.15 12.6 0.5 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding PPP1R35_C PF15503.6 PVD36835.1 - 1.3e-09 38.0 0.3 1.3e-09 38.0 0.3 2.7 3 0 0 3 3 3 1 Protein phosphatase 1 regulatory subunit 35 C-terminus zf-C2H2_4 PF13894.6 PVD36835.1 - 0.00026 21.6 8.0 0.047 14.5 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PVD36835.1 - 0.0019 18.5 4.0 1 9.9 0.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 PVD36835.1 - 0.01 16.2 2.5 0.1 13.1 0.8 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Reeler PF02014.16 PVD36836.1 - 6.2e-06 27.0 0.0 8.7e-05 23.3 0.0 2.5 1 1 1 2 2 2 1 Reeler domain Lectin_C PF00059.21 PVD36837.1 - 1.1e-10 42.2 8.3 2.6e-07 31.3 0.3 2.7 3 0 0 3 3 3 2 Lectin C-type domain DUF4531 PF15041.6 PVD36837.1 - 0.0036 17.4 4.8 0.038 14.1 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4531) V-set_2 PF15910.5 PVD36837.1 - 0.49 10.5 2.4 4.9 7.3 0.3 2.3 1 1 1 2 2 2 0 ICOS V-set domain PHD_3 PF13922.6 PVD36838.1 - 0.017 15.5 0.8 0.12 12.7 0.2 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Guanylate_cyc PF00211.20 PVD36839.1 - 7e-62 208.3 0.2 1.4e-61 207.4 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD36839.1 - 6.8e-08 32.2 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated DUF5405 PF17399.2 PVD36839.1 - 0.02 15.1 0.1 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) WD40 PF00400.32 PVD36840.1 - 6.6e-40 134.4 5.1 9.8e-07 29.4 1.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 PVD36840.1 - 7e-27 93.0 0.0 1.5e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 PVD36840.1 - 5e-19 68.4 0.0 8.6e-05 22.8 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD36840.1 - 4.5e-07 29.1 1.5 0.0032 16.5 0.4 4.1 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PVD36840.1 - 0.00026 20.9 0.0 0.015 15.2 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A BING4CT PF08149.11 PVD36840.1 - 0.012 15.5 0.1 24 4.8 0.0 3.6 3 0 0 3 3 3 0 BING4CT (NUC141) domain Frtz PF11768.8 PVD36840.1 - 0.023 13.0 0.0 0.23 9.8 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 PVD36840.1 - 0.045 12.3 0.0 0.096 11.2 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain BBS2_Mid PF14783.6 PVD36840.1 - 0.087 12.9 0.0 16 5.6 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M13_N PF05649.13 PVD36841.1 - 4.2e-77 260.4 3.7 6e-77 259.9 3.7 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36841.1 - 8.7e-75 250.8 0.1 1.4e-74 250.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Rax2 PF12768.7 PVD36841.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Sulfotransfer_2 PF03567.14 PVD36843.1 - 6.8e-30 104.8 0.1 4e-29 102.3 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Herpes_IE68 PF02479.16 PVD36843.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus immediate early protein Kinesin PF00225.23 PVD36844.1 - 2e-98 329.4 0.8 2e-98 329.4 0.8 4.0 3 2 2 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 PVD36844.1 - 1.4e-14 54.2 0.0 1.4e-14 54.2 0.0 4.3 2 2 0 3 3 3 2 Microtubule binding DUF745 PF05335.13 PVD36844.1 - 0.0049 16.6 8.4 0.0049 16.6 8.4 7.4 5 1 4 9 9 9 1 Protein of unknown function (DUF745) MethyTransf_Reg PF10119.9 PVD36844.1 - 0.039 14.7 0.1 0.34 11.7 0.1 2.8 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain DUF3800 PF12686.7 PVD36844.1 - 6.4 7.4 19.5 1.5e+03 -0.3 0.0 5.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) SlyX PF04102.12 PVD36845.1 - 0.0025 18.4 2.7 0.0025 18.4 2.7 13.2 6 3 7 14 14 14 3 SlyX GAS PF13851.6 PVD36845.1 - 0.0033 16.8 12.5 0.0033 16.8 12.5 10.3 2 1 8 11 11 11 2 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 PVD36845.1 - 0.0033 17.2 1.4 0.0033 17.2 1.4 10.2 11 1 1 12 12 12 2 Coiled-coil N-terminus of cGMP-dependent protein kinase NdhM PF10664.9 PVD36845.1 - 0.074 13.3 2.6 0.11 12.8 0.2 2.6 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M Motilin_ghrelin PF04644.12 PVD36845.1 - 3 7.7 9.8 0.39 10.6 1.9 3.6 3 0 0 3 3 3 0 Motilin/ghrelin 7tm_1 PF00001.21 PVD36846.1 - 2.1e-24 86.3 18.2 3.8e-17 62.5 8.0 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) OSTbeta PF15048.6 PVD36846.1 - 0.0026 17.9 0.1 0.0026 17.9 0.1 2.2 3 0 0 3 3 3 1 Organic solute transporter subunit beta protein Wzy_C PF04932.15 PVD36846.1 - 0.23 11.1 8.6 0.44 10.2 0.1 3.4 3 1 0 3 3 3 0 O-Antigen ligase BatD PF13584.6 PVD36846.1 - 0.38 9.5 3.5 1.1 8.0 1.4 2.1 1 1 1 2 2 2 0 Oxygen tolerance DUF4834 PF16118.5 PVD36846.1 - 4.7 8.3 5.5 1.7 9.7 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 PVD36846.1 - 9.3 6.6 17.1 0.2 12.0 0.7 3.9 4 1 0 4 4 4 0 Orf78 (ac78) DUF3886 PF13025.6 PVD36847.1 - 0.096 12.9 0.0 6.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF4957 PF16318.5 PVD36847.1 - 0.19 11.7 0.2 15 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) DUF2142 PF09913.9 PVD36848.1 - 0.012 14.5 1.0 0.24 10.2 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) DUF4131 PF13567.6 PVD36848.1 - 0.046 13.4 1.1 2.4 7.8 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) SirB PF04247.12 PVD36848.1 - 0.066 13.3 0.8 2.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB YhhN PF07947.14 PVD36848.1 - 0.073 12.7 1.3 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 YhhN family TctA PF01970.16 PVD36848.1 - 0.11 11.1 0.2 0.25 10.0 0.1 1.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family DUF5437 PF17505.2 PVD36848.1 - 0.17 11.9 0.8 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5437) DUF423 PF04241.15 PVD36848.1 - 0.42 10.8 2.5 0.92 9.7 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF423) DUF4148 PF13663.6 PVD36848.1 - 0.43 10.8 1.3 33 4.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF998 PF06197.13 PVD36848.1 - 3.4 7.2 8.6 3.8 7.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) LIM PF00412.22 PVD36853.1 - 2.7e-29 101.1 35.6 2.9e-12 46.6 8.6 4.0 4 0 0 4 4 4 3 LIM domain ParcG PF10274.9 PVD36853.1 - 0.23 11.6 1.6 0.59 10.2 0.1 2.4 3 0 0 3 3 3 0 Parkin co-regulated protein EF-hand_7 PF13499.6 PVD36854.1 - 1.6e-23 82.9 3.9 6.8e-11 42.5 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD36854.1 - 1.6e-20 71.0 8.2 7.7e-07 28.2 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD36854.1 - 8.1e-19 65.9 5.0 4.8e-05 23.0 0.0 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PVD36854.1 - 1.5e-16 60.0 3.5 1.6e-06 27.9 0.3 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD36854.1 - 1.7e-10 39.9 3.6 0.00019 20.8 0.4 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 PVD36854.1 - 2.7e-05 24.4 0.1 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 PVD36854.1 - 0.0011 19.8 0.2 1.1 10.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 PVD36854.1 - 0.0018 18.6 0.4 0.79 10.1 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 PVD36854.1 - 0.0026 17.6 0.2 0.56 10.1 0.1 2.4 2 0 0 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 PVD36854.1 - 0.0029 17.9 0.2 2 8.7 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PVD36854.1 - 0.0045 16.9 0.2 0.96 9.4 0.1 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 PVD36854.1 - 0.012 14.2 0.0 0.25 9.8 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5580) GhoS PF11080.8 PVD36854.1 - 0.032 14.2 0.3 0.17 11.9 0.1 2.2 2 1 1 3 3 3 0 Endoribonuclease GhoS THF_DHG_CYH PF00763.23 PVD36854.1 - 0.054 13.8 0.1 0.19 12.0 0.0 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OTU PF02338.19 PVD36855.1 - 8.5e-10 39.2 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PVD36855.1 - 1.7e-05 24.4 0.3 0.056 12.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain HBS1_N PF08938.10 PVD36855.1 - 0.00016 21.9 0.3 0.00045 20.5 0.1 1.9 2 0 0 2 2 2 1 HBS1 N-terminus UBA PF00627.31 PVD36855.1 - 0.022 14.7 0.6 0.05 13.5 0.6 1.7 1 0 0 1 1 1 0 UBA/TS-N domain IMUP PF15761.5 PVD36855.1 - 2.3 9.0 7.1 1.8 9.3 2.8 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Cation_efflux PF01545.21 PVD36856.1 - 1.2e-26 93.6 7.6 1.5e-26 93.4 7.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PVD36856.1 - 6.3e-09 35.9 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter mono-CXXC PF15626.6 PVD36856.1 - 0.073 13.4 1.1 0.17 12.3 1.1 1.6 1 0 0 1 1 1 0 single CXXC unit Peptidase_M13_N PF05649.13 PVD36857.1 - 5.3e-19 69.2 0.0 6.3e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD36858.1 - 4.1e-167 552.3 0.9 2.1e-57 194.1 0.0 6.2 5 1 1 6 6 6 5 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD36858.1 - 4.8e-61 207.6 1.8 3.4e-21 76.4 0.0 7.1 5 2 2 7 7 7 5 Peptidase family M13 PIN_2 PF10130.9 PVD36858.1 - 0.00014 22.1 1.9 0.4 10.9 0.2 2.5 2 0 0 2 2 2 2 PIN domain Arg_decarbox_C PF17944.1 PVD36858.1 - 0.072 13.7 0.2 38 4.9 0.0 3.4 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension PYRIN PF02758.16 PVD36858.1 - 0.17 12.0 0.5 30 4.9 0.1 2.8 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain DUF4157 PF13699.6 PVD36858.1 - 0.2 11.9 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Peptidase_M13 PF01431.21 PVD36859.1 - 2e-56 190.9 0.7 9.6e-30 103.7 0.0 4.8 3 2 2 5 5 5 4 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD36859.1 - 1.1e-17 64.8 0.0 3.8e-11 43.3 0.2 3.1 2 1 1 3 3 3 3 Peptidase family M13 PBD PF00786.28 PVD36859.1 - 0.16 12.4 0.3 1.8e+02 2.5 0.0 3.8 4 0 0 4 4 4 0 P21-Rho-binding domain Colipase_C PF02740.14 PVD36859.1 - 0.17 12.1 0.2 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Colipase, C-terminal domain BNR_6 PF15899.5 PVD36859.1 - 1.4 9.1 5.8 36 4.8 0.1 3.5 3 0 0 3 3 3 0 BNR-Asp box repeat Peptidase_M13 PF01431.21 PVD36860.1 - 1.3e-64 217.5 2.7 1.1e-43 149.2 0.1 3.2 2 1 1 3 3 3 3 Peptidase family M13 Peptidase_M13_N PF05649.13 PVD36860.1 - 2e-15 57.4 2.2 7.2e-08 32.5 0.0 2.6 3 0 0 3 3 3 2 Peptidase family M13 Peptidase_M48 PF01435.18 PVD36860.1 - 0.01 15.7 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M48 Peptidase_M13 PF01431.21 PVD36861.1 - 3.8e-08 33.2 2.1 0.00011 21.9 0.5 2.1 1 1 1 2 2 2 2 Peptidase family M13 AIP3 PF03915.13 PVD36862.1 - 4.7e-15 55.6 11.0 4.7e-15 55.6 11.0 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 zf-B_box PF00643.24 PVD36862.1 - 1.7e-08 34.5 6.7 1.7e-08 34.5 6.7 4.5 4 1 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 PVD36862.1 - 3.3e-06 27.0 12.0 3.3e-06 27.0 12.0 2.8 4 0 0 4 4 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD36862.1 - 4.4e-06 26.4 13.9 4.4e-06 26.4 13.9 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD36862.1 - 6.4e-06 26.0 12.2 6.4e-06 26.0 12.2 3.5 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PVD36862.1 - 1.7e-05 24.6 11.0 1.7e-05 24.6 11.0 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD36862.1 - 3e-05 23.8 13.5 3e-05 23.8 13.5 4.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36862.1 - 0.00053 20.3 12.4 0.00053 20.3 12.4 3.4 3 0 0 3 3 2 1 Ring finger domain Mu-like_Com PF10122.9 PVD36862.1 - 0.0011 18.4 3.2 0.004 16.6 3.2 2.0 1 0 0 1 1 1 1 Mu-like prophage protein Com zf-C3HC4_4 PF15227.6 PVD36862.1 - 0.012 15.8 13.8 0.012 15.8 13.8 3.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING CEBP_ZZ PF16366.5 PVD36862.1 - 0.022 15.0 7.7 0.022 15.0 7.7 3.4 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ATP-gua_Ptrans PF00217.19 PVD36862.1 - 0.023 14.2 0.1 0.064 12.7 0.1 1.7 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain FUSC-like PF12805.7 PVD36862.1 - 0.11 11.6 9.1 0.16 11.1 0.6 2.6 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS ATPase PF06745.13 PVD36862.1 - 0.2 11.0 4.0 0.37 10.1 0.4 2.4 2 0 0 2 2 2 0 KaiC FUSC PF04632.12 PVD36862.1 - 1.7 7.1 10.9 0.25 9.8 5.9 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1359 PF07097.11 PVD36862.1 - 8.5 6.7 7.4 0.59 10.4 0.7 2.6 3 1 0 3 3 2 0 Protein of unknown function (DUF1359) COesterase PF00135.28 PVD36863.1 - 1.8e-100 337.2 0.0 6.4e-81 272.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36863.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD36864.1 - 1.3e-248 826.0 0.0 7e-125 417.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36864.1 - 1.6e-18 67.3 0.6 5.8e-09 36.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Conotoxin PF02950.17 PVD36864.1 - 0.076 14.0 0.3 4.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Conotoxin COesterase PF00135.28 PVD36865.1 - 1.5e-101 340.8 0.0 2.1e-89 300.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36865.1 - 1.6e-08 34.6 0.1 3.5e-08 33.6 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD36866.1 - 1.7e-123 413.2 0.0 6.4e-123 411.3 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36866.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD36867.1 - 8.8e-256 849.7 0.0 8.2e-128 427.5 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36867.1 - 8.7e-12 45.3 3.4 1.9e-07 31.1 0.1 3.6 3 2 0 3 3 3 2 alpha/beta hydrolase fold DICT PF10069.9 PVD36867.1 - 0.069 12.9 0.0 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system COesterase PF00135.28 PVD36868.1 - 3e-235 781.9 0.0 2.3e-110 369.9 0.0 4.0 2 2 1 4 4 4 4 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36868.1 - 2.2e-16 60.4 1.6 3.9e-07 30.1 0.1 2.9 2 2 0 2 2 2 2 alpha/beta hydrolase fold DICT PF10069.9 PVD36868.1 - 0.07 12.9 0.0 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system COesterase PF00135.28 PVD36869.1 - 1.4e-122 410.2 0.0 1.6e-122 410.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD36869.1 - 2.2e-11 44.0 0.0 4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_tran_10_N PF17039.5 PVD36870.1 - 2.9e-21 76.0 2.4 5.5e-21 75.1 0.1 2.5 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD36870.1 - 8.2e-21 74.5 0.3 5.8e-12 45.7 0.0 2.7 2 1 1 3 3 3 2 Glycosyltransferase family 10 (fucosyltransferase) C-term PLAC8 PF04749.17 PVD36870.1 - 1e-11 45.7 13.8 1e-11 45.7 13.8 1.9 2 0 0 2 2 2 1 PLAC8 family Glyco_transf_10 PF00852.19 PVD36871.1 - 6.7e-39 133.4 0.1 7.5e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Pantoate_ligase PF02569.15 PVD36871.1 - 0.071 12.3 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Glyco_tran_10_N PF17039.5 PVD36872.1 - 4.8e-22 78.5 0.2 9.5e-22 77.6 0.2 1.6 1 1 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 PVD36873.1 - 2.4e-49 167.4 1.4 2.9e-49 167.2 0.6 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD36873.1 - 6.4e-20 71.7 0.4 2.3e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Anp1 PF03452.14 PVD36874.1 - 5.4e-08 32.6 0.1 0.0065 15.9 0.0 2.6 2 1 1 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 PVD36874.1 - 6.9e-05 23.7 0.2 0.00022 22.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PP2C PF00481.21 PVD36876.1 - 7.3e-50 170.0 0.1 1.1e-48 166.2 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PVD36876.1 - 3.4e-05 23.6 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3666 PF12408.8 PVD36876.1 - 0.085 12.1 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Aldedh PF00171.22 PVD36878.1 - 2.4e-97 326.4 0.0 7.5e-97 324.7 0.0 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family NMD3 PF04981.13 PVD36878.1 - 0.028 13.9 0.1 0.85 9.0 0.1 2.2 2 0 0 2 2 2 0 NMD3 family DUF1681 PF07933.14 PVD36879.1 - 2.8e-57 192.6 0.0 3.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Death PF00531.22 PVD36880.1 - 1.3e-07 31.7 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Death domain MetW PF07021.12 PVD36880.1 - 0.081 12.5 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Death PF00531.22 PVD36881.1 - 0.00035 20.7 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 Death domain DUF1040 PF06288.13 PVD36881.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) Peptidase_M14 PF00246.24 PVD36882.1 - 1.4e-26 94.0 0.0 1.5e-24 87.3 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 PVD36882.1 - 9.6e-09 35.5 0.1 1.5e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 PVD36883.1 - 5.1e-65 220.1 0.5 7e-65 219.7 0.5 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 PVD36883.1 - 4.1e-11 43.1 0.5 8.1e-11 42.2 0.5 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Pyridoxal_deC PF00282.19 PVD36884.1 - 1.7e-103 346.2 0.0 2.1e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PVD36884.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Methyltr_RsmB-F PF01189.17 PVD36885.1 - 2.2e-77 259.2 0.0 3.6e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 PVD36885.1 - 1.8e-08 34.8 0.0 4.9e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 PVD36885.1 - 0.00064 19.9 0.0 0.003 17.7 0.0 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase RRN3 PF05327.11 PVD36885.1 - 0.0063 15.1 2.7 0.0097 14.5 2.7 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Met_10 PF02475.16 PVD36885.1 - 0.025 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Glyco_transf_92 PF01697.27 PVD36886.1 - 3.9e-26 92.3 0.3 9.1e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PVD36886.1 - 0.047 14.2 0.0 0.17 12.4 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 Exo84_C PF16528.5 PVD36887.1 - 6.7e-55 186.1 0.1 1.7e-54 184.8 0.0 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 PVD36887.1 - 4.3e-15 55.5 0.6 1.5e-14 53.8 0.6 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 PVD36887.1 - 0.00058 20.0 0.1 0.0057 16.7 0.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 HIP1_clath_bdg PF16515.5 PVD36887.1 - 5 7.8 12.9 3.6 8.3 6.7 3.6 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 PVD36888.1 - 1.7e-20 73.5 0.0 2e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 PVD36888.1 - 3.7e-13 49.7 15.8 1.7e-06 28.6 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 PVD36888.1 - 1.5e-06 27.7 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 PVD36888.1 - 3.5e-06 26.8 0.4 0.49 10.8 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat ANAPC4_WD40 PF12894.7 PVD36888.1 - 0.0044 17.3 0.3 5.8 7.3 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1137 PF06587.11 PVD36888.1 - 0.052 13.6 0.1 0.25 11.3 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) TTL PF03133.15 PVD36889.1 - 2e-30 106.0 3.0 4.3e-30 104.8 3.0 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Peptidase_C98 PF15499.6 PVD36889.1 - 0.019 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RhoGEF PF00621.20 PVD36889.1 - 0.65 10.2 3.7 15 5.7 0.8 2.1 2 0 0 2 2 2 0 RhoGEF domain NLPC_P60 PF00877.19 PVD36890.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 NlpC/P60 family DUF4710 PF15828.5 PVD36890.1 - 0.19 11.9 6.6 0.57 10.3 6.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Zip PF02535.22 PVD36890.1 - 0.28 10.3 0.4 0.45 9.7 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 PVD36890.1 - 0.37 9.5 3.6 0.64 8.7 3.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 PVD36890.1 - 4.7 5.9 4.7 7.6 5.2 4.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 PVD36890.1 - 7.5 6.3 8.7 17 5.2 8.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Potass_KdpF PF09604.10 PVD36891.1 - 0.42 10.6 2.7 0.73 9.9 2.7 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Atrophin-1 PF03154.15 PVD36894.1 - 6.1 5.0 10.9 12 4.1 10.9 1.4 1 0 0 1 1 1 0 Atrophin-1 family DnaJ PF00226.31 PVD36895.1 - 1.4e-26 92.3 3.3 1.4e-25 89.2 0.9 2.6 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 PVD36895.1 - 2.5e-06 27.4 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin K_trans PF02705.16 PVD36895.1 - 0.15 10.5 0.2 0.29 9.6 0.2 1.3 1 0 0 1 1 1 0 K+ potassium transporter Glyco_hydro_9 PF00759.19 PVD36896.1 - 5e-111 372.0 4.9 8.1e-110 368.1 4.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 PI3_PI4_kinase PF00454.27 PVD36900.1 - 6.9e-51 173.5 0.8 1.3e-49 169.2 0.8 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PVD36900.1 - 4.5e-49 166.4 6.1 9e-49 165.4 6.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 PVD36900.1 - 3.7e-22 77.8 0.5 3.7e-21 74.6 0.1 2.5 2 0 0 2 2 2 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 PVD36900.1 - 4.8e-19 68.5 0.0 1.4e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 PVD36900.1 - 2.4e-12 47.0 0.0 5.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 PVD36900.1 - 0.00073 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) CRAL_TRIO_N PF03765.15 PVD36900.1 - 0.59 10.4 4.7 17 5.7 1.3 2.7 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain LPMO_10 PF03067.15 PVD36901.1 - 1.3e-18 68.4 0.0 1.5e-18 68.2 0.0 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_79n PF03662.14 PVD36902.1 - 1.5e-16 60.3 0.2 2.1e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Ank_2 PF12796.7 PVD36903.1 - 1.8e-24 86.1 5.9 7e-07 29.7 0.2 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD36903.1 - 1.1e-23 82.9 8.4 6.7e-08 32.7 0.1 6.1 3 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PVD36903.1 - 5.6e-23 80.3 4.1 9.1e-06 25.9 0.4 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PVD36903.1 - 6e-23 80.9 3.1 5.7e-05 23.6 0.1 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) MIB_HERC2 PF06701.13 PVD36903.1 - 1.9e-21 76.0 1.5 8.4e-21 74.0 1.5 2.2 1 0 0 1 1 1 1 Mib_herc2 SH3_15 PF18346.1 PVD36903.1 - 2.7e-20 72.5 0.3 4.9e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_3 PF13606.6 PVD36903.1 - 3.4e-16 57.7 7.2 0.0011 19.2 0.1 7.0 8 0 0 8 8 8 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 PVD36903.1 - 1e-05 25.2 11.9 2.1e-05 24.3 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DSBA PF01323.20 PVD36904.1 - 1.3e-25 90.3 0.0 1.4e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Catalase-rel PF06628.12 PVD36904.1 - 0.1 12.8 0.1 8.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive EMC1_C PF07774.13 PVD36905.1 - 4.1e-50 170.4 0.1 6.5e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 PVD36905.1 - 0.00029 20.5 0.1 0.48 9.9 0.1 3.0 2 1 0 2 2 2 2 PQQ-like domain Pkinase_Tyr PF07714.17 PVD36906.1 - 2.9e-54 184.1 0.1 5.6e-40 137.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD36906.1 - 2.2e-24 86.2 0.0 5e-15 55.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain GTPase_binding PF09027.10 PVD36906.1 - 2.2e-21 75.6 0.3 5e-21 74.4 0.3 1.6 1 0 0 1 1 1 1 GTPase binding SH3_9 PF14604.6 PVD36906.1 - 6.6e-08 32.3 0.0 1.9e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD36906.1 - 7.5e-06 25.5 0.0 1.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD36906.1 - 8.7e-06 25.3 0.3 1.9e-05 24.2 0.3 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 PVD36907.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 PH domain PH PF00169.29 PVD36908.1 - 8.6e-09 35.9 0.0 1.8e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Rpp20 PF12328.8 PVD36908.1 - 0.074 13.0 0.6 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Phage_TAC_10 PF10963.8 PVD36908.1 - 0.079 13.1 0.1 4.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Phage tail assembly chaperone PH PF00169.29 PVD36909.1 - 0.00042 20.8 1.5 0.0013 19.3 0.4 2.3 2 0 0 2 2 2 1 PH domain Tmem26 PF09772.9 PVD36910.1 - 3.2e-93 312.2 12.1 3.8e-93 312.0 12.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 7tm_1 PF00001.21 PVD36912.1 - 0.00045 19.6 3.5 0.00045 19.6 3.5 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) T4SS_CagC PF16943.5 PVD36912.1 - 0.097 12.9 1.5 0.21 11.8 1.5 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system 7tm_1 PF00001.21 PVD36913.1 - 8.8e-10 38.3 1.6 8.8e-10 38.3 1.6 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3147 PF11345.8 PVD36913.1 - 0.028 14.8 0.7 0.084 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Atrophin-1 PF03154.15 PVD36915.1 - 6.1e-42 144.0 57.5 3.7e-41 141.4 55.6 2.9 2 1 0 2 2 2 1 Atrophin-1 family BAH PF01426.18 PVD36916.1 - 2.9e-18 65.9 0.0 9.9e-18 64.2 0.0 1.9 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 PVD36916.1 - 5.9e-10 39.8 0.0 5.9e-10 39.8 0.0 2.3 3 0 0 3 3 3 1 ELM2 domain GATA PF00320.27 PVD36916.1 - 2.1e-07 30.4 2.8 4.1e-07 29.5 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 PVD36916.1 - 4.1e-05 23.7 0.4 0.00012 22.2 0.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PVD36916.1 - 0.00072 19.4 0.3 0.0018 18.1 0.3 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PVD36916.1 - 0.02 15.2 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF5540 PF17694.1 PVD36916.1 - 0.38 11.3 4.2 0.81 10.2 0.8 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5540) PID PF00640.23 PVD36917.1 - 7.9e-13 48.6 0.1 2.2e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 PVD36917.1 - 2.8e-08 33.7 0.0 9.8e-08 32.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Suppressor_APC PF11414.8 PVD36917.1 - 4.6 7.4 7.3 0.3 11.2 0.6 2.6 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein RhoGEF PF00621.20 PVD36918.1 - 1.7e-30 106.6 4.3 3.3e-30 105.7 4.3 1.4 1 0 0 1 1 1 1 RhoGEF domain SIT PF15330.6 PVD36918.1 - 0.081 13.4 3.6 0.12 12.8 0.5 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Aminotran_5 PF00266.19 PVD36919.1 - 4.3e-11 42.4 0.0 2.7e-09 36.5 0.0 2.7 1 1 2 3 3 3 3 Aminotransferase class-V GST_C_3 PF14497.6 PVD36920.1 - 3.7e-11 43.1 0.1 7.5e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD36920.1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CRT-like PF08627.10 PVD36922.1 - 5.1e-16 58.5 5.0 2.2e-12 46.6 1.2 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Ycf9 PF01737.17 PVD36922.1 - 0.0019 18.0 8.3 0.0075 16.1 8.3 2.1 1 0 0 1 1 1 1 YCF9 DUF3742 PF12553.8 PVD36922.1 - 0.88 9.7 4.0 0.77 9.9 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DED PF01335.21 PVD36923.1 - 0.0031 17.8 0.2 0.011 16.0 0.2 2.0 1 0 0 1 1 1 1 Death effector domain Nucleic_acid_bd PF13820.6 PVD36923.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Putative nucleic acid-binding region GST_C_2 PF13410.6 PVD36924.1 - 9.9e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD36924.1 - 2.8e-05 24.4 0.0 5.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PVD36924.1 - 0.0023 18.1 0.0 0.0044 17.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1972 PF09314.11 PVD36924.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1972) Acetyltransf_17 PF17668.1 PVD36924.1 - 0.12 13.1 0.0 10 6.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M10 PF00413.24 PVD36925.1 - 5.3e-35 120.6 1.8 3.3e-34 118.0 0.7 2.2 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.19 PVD36925.1 - 1.2e-10 41.2 6.9 1.9e-06 27.7 0.2 3.7 3 0 0 3 3 3 2 Hemopexin PG_binding_1 PF01471.18 PVD36925.1 - 2.5e-07 30.8 0.0 3.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Peptidase_M54 PF07998.11 PVD36925.1 - 0.0058 16.6 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M66 PF10462.9 PVD36925.1 - 0.08 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 PVD36925.1 - 0.084 12.5 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 PVD36925.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD36925.1 - 0.19 11.6 0.3 0.45 10.4 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD36925.1 - 0.23 12.0 0.6 0.48 10.9 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.25 PVD36926.1 - 3.4e-65 220.0 0.0 4e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD36926.1 - 7e-33 114.0 0.0 9.2e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PVD36926.1 - 2.1e-07 31.6 0.3 3.9e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 PVD36926.1 - 1.4e-05 24.5 0.0 3.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD36926.1 - 0.0047 15.9 0.1 0.0069 15.4 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD36926.1 - 0.013 15.5 0.2 0.041 13.8 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 PVD36926.1 - 0.02 14.5 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PVD36926.1 - 0.038 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F_actin_cap_B PF01115.17 PVD36927.1 - 1.2e-95 319.7 0.3 6.7e-90 300.9 0.0 2.0 1 1 1 2 2 2 2 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 PVD36927.1 - 0.0048 16.4 0.1 0.26 10.7 0.1 2.8 2 1 0 2 2 2 1 F-actin capping protein alpha subunit Cnd1 PF12717.7 PVD36929.1 - 3.3e-52 176.8 6.5 2.9e-49 167.2 0.1 4.3 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 PVD36929.1 - 2.7e-30 105.4 0.0 2.7e-30 105.4 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 PVD36929.1 - 1.5e-05 25.3 0.2 0.17 12.3 0.0 5.3 4 1 1 5 5 5 1 HEAT repeats Cnd3 PF12719.7 PVD36929.1 - 4.8e-05 22.7 0.3 0.00024 20.4 0.3 2.3 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 PVD36929.1 - 9.7e-05 22.3 25.0 0.05 13.9 0.1 9.2 12 0 0 12 12 12 2 HEAT repeat RTP1_C1 PF10363.9 PVD36929.1 - 0.0051 17.0 0.5 0.69 10.1 0.1 3.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 PVD36929.1 - 0.0057 17.1 8.2 5.8 7.5 0.1 6.0 5 1 2 7 7 7 1 HEAT-like repeat DUF4042 PF13251.6 PVD36929.1 - 0.038 13.7 0.1 0.97 9.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 PVD36929.1 - 0.83 10.0 3.2 2.9 8.3 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HupE_UreJ_2 PF13795.6 PVD36933.1 - 0.058 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 HupE / UreJ protein Hamartin PF04388.12 PVD36934.1 - 6.2 5.3 13.6 0.38 9.4 8.6 1.4 2 0 0 2 2 2 0 Hamartin protein UreD PF01774.17 PVD36935.1 - 1.9e-49 168.5 0.0 3e-49 167.8 0.0 1.3 2 0 0 2 2 2 1 UreD urease accessory protein RRM_1 PF00076.22 PVD36936.1 - 9.4e-20 70.2 0.0 1.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC53 PF10152.9 PVD36936.1 - 1.1 9.7 7.5 4.2 7.8 3.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF726 PF05277.12 PVD36937.1 - 4e-131 437.0 1.6 5.6e-131 436.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 PVD36937.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 PVD36937.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PE-PPE PF08237.11 PVD36937.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 PVD36937.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) LAP1C PF05609.12 PVD36938.1 - 5.5 6.0 17.9 4.8 6.2 0.1 2.2 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF3320 PF11784.8 PVD36939.1 - 2.9e-06 27.1 18.4 24 5.0 0.0 13.3 13 2 3 16 16 16 1 Protein of unknown function (DUF3320) CMAS PF02353.20 PVD36939.1 - 9.2e-05 21.9 2.6 63 2.7 0.0 8.4 3 3 4 9 9 9 0 Mycolic acid cyclopropane synthetase ANP PF00212.18 PVD36939.1 - 0.035 14.3 123.0 0.99 9.6 1.3 23.8 27 0 0 27 27 27 0 Atrial natriuretic peptide Serpin PF00079.20 PVD36940.1 - 1.1e-05 24.9 0.0 1.2e-05 24.8 0.0 1.2 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) 7tm_2 PF00002.24 PVD36941.1 - 1.1e-20 73.9 13.5 1.8e-13 50.4 5.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 PVD36941.1 - 0.53 9.1 9.7 0.16 10.9 1.9 2.4 2 1 0 2 2 2 0 Ocular albinism type 1 protein Sigma70_r4 PF04545.16 PVD36942.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 UL42 PF17638.2 PVD36943.1 - 1 9.3 4.2 1.5 8.8 4.2 1.3 1 0 0 1 1 1 0 HCMV UL42 C5-epim_C PF06662.13 PVD36944.1 - 2.8e-69 232.4 0.0 4.6e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus RPE65 PF03055.15 PVD36945.1 - 4.5e-125 418.4 0.1 3.1e-99 333.3 0.1 2.4 2 1 0 2 2 2 2 Retinal pigment epithelial membrane protein Beta-Casp PF10996.8 PVD36945.1 - 1.3e-24 86.6 0.0 6.2e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Tmem26 PF09772.9 PVD36945.1 - 4.1e-18 65.8 1.9 4.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Transmembrane protein 26 Lactamase_B_6 PF16661.5 PVD36945.1 - 5.5e-16 58.6 0.1 1.2e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 PVD36945.1 - 4.4e-07 29.7 0.0 1.8e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 PVD36945.1 - 8.9e-07 28.6 0.3 1.1e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD36945.1 - 0.0059 16.6 0.4 0.49 10.4 0.4 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 PVD36945.1 - 0.097 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family PhyH PF05721.13 PVD36946.1 - 7.7e-12 45.9 0.1 1.7e-11 44.8 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 PVD36947.1 - 2.6e-10 40.9 0.2 6.1e-10 39.7 0.2 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 PVD36948.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 PVD36949.1 - 0.0042 17.4 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 PVD36950.1 - 1.1e-06 29.0 0.1 0.0059 16.9 0.1 2.2 1 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) An_peroxidase PF03098.15 PVD36952.1 - 3e-155 517.8 0.0 3.5e-155 517.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase OB_NTP_bind PF07717.16 PVD36953.1 - 9.3e-20 70.8 0.0 1.8e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PVD36953.1 - 1.1e-16 61.1 0.0 1.1e-16 61.1 0.0 2.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 PVD36953.1 - 1.7e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PVD36953.1 - 0.0075 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PVD36953.1 - 0.008 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 PVD36953.1 - 0.0091 16.0 0.1 1.4 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 PVD36953.1 - 0.025 13.9 0.4 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 PVD36953.1 - 0.045 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 PVD36953.1 - 0.067 13.5 4.0 0.41 10.9 1.7 3.2 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PVD36953.1 - 0.087 13.2 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PVD36953.1 - 0.089 13.3 1.9 0.72 10.4 0.0 3.1 3 1 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 PVD36953.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.2 1 1 1 2 2 1 0 AAA domain Kelch_4 PF13418.6 PVD36954.1 - 6.1e-30 103.0 0.6 1.5e-10 40.9 0.4 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PVD36954.1 - 3.2e-25 87.4 0.6 3.4e-08 32.9 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PVD36954.1 - 5.5e-25 87.1 6.2 1.1e-09 38.3 0.2 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD36954.1 - 3.8e-22 77.8 4.6 7.4e-06 26.1 0.3 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PVD36954.1 - 8.1e-22 76.3 6.6 1.8e-07 30.8 0.1 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PVD36954.1 - 7.6e-19 67.3 7.2 7.3e-06 25.9 0.1 6.3 6 0 0 6 6 6 5 Kelch motif F-box-like PF12937.7 PVD36954.1 - 9.2e-11 41.5 0.0 3.3e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD36954.1 - 1.7e-05 24.5 0.2 4.6e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD36954.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box Peptidase_C14 PF00656.22 PVD36955.1 - 1.6e-30 106.8 0.0 2.8e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 PVD36955.1 - 4.8e-12 45.7 2.0 1e-11 44.7 2.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD36955.1 - 7.9e-05 22.6 0.4 0.00015 21.7 0.4 1.5 1 0 0 1 1 1 1 Caspase recruitment domain zf-C2H2 PF00096.26 PVD36957.1 - 4.3e-27 93.0 46.4 7.6e-08 32.4 0.3 6.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD36957.1 - 3.9e-19 67.7 36.6 0.00025 21.6 0.2 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD36957.1 - 5.1e-13 48.8 37.5 0.00024 21.4 0.8 7.3 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD36957.1 - 1.2e-06 28.6 18.4 0.00058 20.1 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD36957.1 - 1.3e-06 28.3 30.4 0.55 10.3 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD36957.1 - 3.7e-06 26.6 23.5 0.031 14.0 0.4 5.5 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 PVD36957.1 - 4e-05 23.8 20.2 0.078 13.3 11.4 3.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 PVD36957.1 - 5.2e-05 22.9 5.1 0.0012 18.5 2.0 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 PVD36957.1 - 7.5e-05 23.0 11.0 0.011 16.1 0.1 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 PVD36957.1 - 0.00048 19.7 17.5 2.2 8.0 0.9 5.7 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 PVD36957.1 - 0.012 15.7 25.0 4.3 7.5 0.2 5.0 3 1 1 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.11 PVD36957.1 - 0.2 11.6 15.3 7.1 6.6 0.4 5.2 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger XPA_N PF01286.18 PVD36957.1 - 0.44 10.6 15.6 1.7 8.7 0.2 5.0 5 0 0 5 5 5 0 XPA protein N-terminal zinc_ribbon_5 PF13719.6 PVD36957.1 - 1.4 8.8 14.8 11 5.8 0.0 5.3 5 0 0 5 5 5 0 zinc-ribbon domain zf-trcl PF13451.6 PVD36957.1 - 7.2 6.6 20.7 5.7 6.9 0.3 5.0 5 0 0 5 5 5 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 PVD36957.1 - 8.5 6.4 18.5 33 4.5 3.8 5.1 4 1 0 4 4 4 0 zinc-ribbon domain Exo_endo_phos_2 PF14529.6 PVD36961.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD36961.1 - 0.011 15.3 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FapA PF03961.13 PVD36962.1 - 0.13 10.8 1.5 0.15 10.6 1.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNase_H2-Ydr279 PF09468.10 PVD36962.1 - 0.66 10.1 4.5 11 6.2 0.0 2.1 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Milton PF12448.8 PVD36965.1 - 0.035 14.2 1.9 0.04 14.0 1.9 1.2 1 0 0 1 1 1 0 Kinesin associated protein 7tm_1 PF00001.21 PVD36966.1 - 0.00015 21.2 1.6 0.00015 21.2 1.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD36966.1 - 0.00055 19.6 5.4 0.00078 19.2 5.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Phage_holin_5_2 PF16079.5 PVD36966.1 - 0.068 13.5 0.2 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V TPR_1 PF00515.28 PVD36967.1 - 0.0031 17.3 0.0 0.054 13.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SUZ PF12752.7 PVD36968.1 - 3.4e-16 59.7 0.3 3.4e-16 59.7 0.3 1.9 2 1 0 2 2 2 1 SUZ domain SUZ-C PF12901.7 PVD36968.1 - 1e-07 31.8 0.6 2.6e-07 30.5 0.6 1.7 1 0 0 1 1 1 1 SUZ-C motif Arr-ms PF12120.8 PVD36968.1 - 0.15 12.3 0.1 0.5 10.6 0.0 1.9 1 1 1 2 2 2 0 Rifampin ADP-ribosyl transferase CENP-S PF15630.6 PVD36969.1 - 2.4e-28 98.3 0.1 2.9e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PVD36969.1 - 2.2e-07 30.9 0.0 3.6e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 PVD36969.1 - 0.0029 18.0 0.1 0.0033 17.8 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Glyco_transf_15 PF01793.16 PVD36969.1 - 0.0055 16.0 0.0 0.0061 15.9 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CENP-S PF15630.6 PVD36970.1 - 2.1e-14 53.7 0.5 3.7e-14 52.8 0.5 1.4 1 0 0 1 1 1 1 CENP-S protein PhyH PF05721.13 PVD36970.1 - 3.6e-09 37.2 0.7 2.4e-08 34.5 0.7 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 PVD36970.1 - 0.0031 16.3 1.3 0.022 13.5 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Glyco_transf_15 PF01793.16 PVD36970.1 - 0.042 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase 7tm_1 PF00001.21 PVD36971.1 - 3.4e-06 26.6 10.9 0.45 9.8 2.6 4.2 4 1 0 4 4 4 3 7 transmembrane receptor (rhodopsin family) APOBEC4_like PF18774.1 PVD36971.1 - 0.049 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Gly_transf_sug PF04488.15 PVD36972.1 - 0.00029 21.4 0.1 0.34 11.6 0.0 2.9 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD36972.1 - 0.012 15.1 0.0 0.073 12.4 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Lectin_C PF00059.21 PVD36973.1 - 2.7e-40 137.4 5.3 1.4e-19 70.8 0.2 2.9 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD36973.1 - 1.1e-06 28.4 1.4 0.00088 19.0 0.5 3.0 2 1 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 PVD36973.1 - 0.00024 20.4 2.6 0.15 11.3 0.2 2.4 2 0 0 2 2 2 2 Chordopoxvirus A33R protein FAM176 PF14851.6 PVD36973.1 - 0.35 10.5 3.2 0.72 9.5 3.2 1.4 1 0 0 1 1 1 0 FAM176 family Tub_N PF16322.5 PVD36973.1 - 0.64 10.4 7.3 1.2 9.5 7.3 1.4 1 0 0 1 1 1 0 Tubby N-terminal PBP1_TM PF14812.6 PVD36973.1 - 0.81 10.1 6.9 2.3 8.6 6.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rootletin PF15035.6 PVD36974.1 - 2.7e-67 226.4 27.4 2.7e-67 226.4 27.4 14.1 7 5 6 13 13 13 4 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 PVD36974.1 - 0.00071 19.5 25.7 0.00071 19.5 25.7 17.7 6 3 9 16 16 16 5 Coiled-coil region of CCDC155 or KASH DUF5082 PF16888.5 PVD36974.1 - 0.0041 17.4 13.1 0.0041 17.4 13.1 19.3 5 4 11 17 17 17 4 Domain of unknown function (DUF5082) DUF3800 PF12686.7 PVD36974.1 - 0.2 12.3 10.3 1.1e+02 3.4 0.0 7.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) UPF0258 PF06789.12 PVD36975.1 - 0.036 14.2 1.2 0.07 13.3 1.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Pex2_Pex12 PF04757.14 PVD36976.1 - 2.3e-25 89.5 1.3 3e-25 89.1 1.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 PVD36976.1 - 8.1e-06 25.6 9.2 1.7e-05 24.6 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD36976.1 - 9.2e-06 25.4 5.7 1.6e-05 24.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD36976.1 - 0.00096 19.0 9.8 0.0021 17.9 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PVD36976.1 - 0.004 17.3 10.0 0.0076 16.4 10.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PVD36976.1 - 0.0049 16.8 8.9 0.011 15.7 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD36976.1 - 0.0067 16.2 10.8 0.013 15.3 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD36976.1 - 0.015 15.6 11.1 0.036 14.4 11.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 PVD36976.1 - 0.021 14.9 6.4 0.042 14.0 6.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 PVD36976.1 - 0.09 12.9 2.8 1.9 8.7 1.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 PVD36976.1 - 1.1 9.3 11.2 2.6 8.1 11.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 PVD36976.1 - 1.8 8.5 5.4 3.8 7.5 5.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ribbon_3 PF13248.6 PVD36976.1 - 9.8 5.7 9.2 2.4 7.7 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbon domain E1-E2_ATPase PF00122.20 PVD36977.1 - 2.2e-31 108.8 0.1 2.2e-31 108.8 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase P5-ATPase PF12409.8 PVD36977.1 - 7.6e-23 81.0 0.1 1.9e-22 79.7 0.1 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 PVD36977.1 - 2.7e-17 63.8 0.0 9.1e-06 26.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 PVD36977.1 - 6.5e-10 39.0 3.9 6.5e-10 39.0 3.9 2.6 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 PVD36977.1 - 4.1e-08 32.8 0.0 1.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PVD36977.1 - 2.7e-05 24.1 0.0 6.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Ribosomal_L22e PF01776.17 PVD36978.1 - 3.6e-51 172.1 2.8 4.6e-51 171.8 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 PVD36978.1 - 0.068 11.9 0.1 0.084 11.6 0.1 1.1 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) AMPK1_CBM PF16561.5 PVD36978.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Adap_comp_sub PF00928.21 PVD36979.1 - 5.6e-81 271.8 0.1 6.8e-81 271.5 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PVD36979.1 - 0.001 19.0 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 PVD36979.1 - 0.031 13.7 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain TPR_12 PF13424.6 PVD36980.1 - 7.2e-12 45.4 0.1 9.5e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD36980.1 - 9.8e-09 34.7 5.8 0.035 14.2 0.0 5.0 6 0 0 6 6 5 3 Tetratricopeptide repeat zf-MYND PF01753.18 PVD36980.1 - 6.9e-08 32.4 12.5 1.8e-07 31.1 12.5 1.8 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.6 PVD36980.1 - 8.1e-08 31.9 0.1 0.93 9.9 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD36980.1 - 4.7e-07 29.4 0.5 0.92 9.4 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD36980.1 - 0.00067 19.1 0.0 0.0077 15.7 0.0 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 PVD36980.1 - 0.002 18.6 0.6 5.4 7.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD36980.1 - 0.058 14.1 1.6 1.9 9.2 0.3 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PVD36980.1 - 0.067 13.2 0.2 20 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD36980.1 - 0.51 10.9 2.5 2.5 8.7 0.1 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 PVD36980.1 - 1.5 9.0 13.9 0.13 12.4 7.4 2.6 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ima1_N PF09779.9 PVD36981.1 - 9.4e-31 107.5 10.7 9.4e-31 107.5 10.7 2.3 3 0 0 3 3 3 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 PVD36981.1 - 0.0024 17.9 9.8 0.01 16.0 9.6 2.2 1 1 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type Pkinase PF00069.25 PVD36982.1 - 1.2e-64 218.2 0.0 2.1e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD36982.1 - 4.2e-29 101.6 0.0 7.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD36982.1 - 2.7e-05 23.6 0.1 2.7e-05 23.6 0.1 2.7 2 1 0 2 2 2 1 Kinase-like UBX PF00789.20 PVD36983.1 - 4.9e-05 23.4 0.0 8.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UVR PF02151.19 PVD36984.1 - 0.0066 16.2 25.3 0.019 14.7 1.9 3.5 4 0 0 4 4 4 2 UvrB/uvrC motif XRCC1_N PF01834.16 PVD36984.1 - 0.036 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 XRCC1 N terminal domain CLASP_N PF12348.8 PVD36984.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 CLASP N terminal DUF1764 PF08576.10 PVD36984.1 - 7 7.6 13.6 1.2 10.1 3.3 3.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DZR PF12773.7 PVD36984.1 - 9.3 6.4 10.0 2.8 8.0 0.7 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-3CxxC PF13695.6 PVD36985.1 - 2e-27 95.6 0.4 3.4e-27 94.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 PVD36985.1 - 0.038 14.7 9.9 13 6.6 0.1 4.0 4 0 0 4 4 4 0 Zinc-binding domain Glyco_hydro_9 PF00759.19 PVD36986.1 - 4.2e-123 411.8 1.8 5e-123 411.6 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 PVD36986.1 - 2.5e-08 34.1 0.0 7.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Cellulose binding domain Glyco_hydro_127 PF07944.12 PVD36986.1 - 0.098 11.1 0.1 0.37 9.2 0.0 1.8 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Aldo_ket_red PF00248.21 PVD36987.1 - 1.1e-36 126.5 0.0 1.3e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rsbr_N PF08678.10 PVD36987.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Rsbr N terminal CAP PF00188.26 PVD36989.1 - 4.1e-23 82.6 0.5 5.9e-23 82.1 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2934 PF11154.8 PVD36989.1 - 0.099 12.3 0.7 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) CARD PF00619.21 PVD36990.1 - 3.6e-06 26.9 2.8 2.6 8.1 0.1 4.2 4 0 0 4 4 4 4 Caspase recruitment domain LexA_DNA_bind PF01726.16 PVD36990.1 - 0.33 10.7 4.0 82 3.1 0.0 4.6 4 0 0 4 4 4 0 LexA DNA binding domain YEATS PF03366.16 PVD36991.1 - 4.8e-34 116.2 0.7 8e-34 115.5 0.7 1.4 1 0 0 1 1 1 1 YEATS family DivIC PF04977.15 PVD36991.1 - 0.023 14.4 2.1 0.046 13.5 2.1 1.5 1 0 0 1 1 1 0 Septum formation initiator IL6 PF00489.17 PVD36991.1 - 0.028 14.0 0.7 0.051 13.1 0.7 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Atg14 PF10186.9 PVD36991.1 - 0.11 11.6 5.1 0.13 11.4 4.2 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 PVD36991.1 - 0.16 12.1 1.8 0.25 11.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DNA_pol_A_exo1 PF01612.20 PVD36992.1 - 2.4e-49 167.4 1.8 3.2e-49 167.0 0.7 1.8 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 PVD36992.1 - 2.8e-18 66.4 0.1 2.8e-18 66.4 0.1 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 PVD36992.1 - 1.3e-12 47.5 0.0 3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF4388 PF14332.6 PVD36992.1 - 0.053 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) CxC6 PF18721.1 PVD36992.1 - 1.4 9.2 3.6 0.66 10.3 0.3 2.1 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Apis_Csd PF11671.8 PVD36992.1 - 2.5 8.1 7.2 5.8 6.9 7.2 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein DUF1980 PF09323.10 PVD36992.1 - 8.8 6.2 8.9 3.2 7.6 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) GFO_IDH_MocA PF01408.22 PVD36993.1 - 6.7e-17 62.4 0.0 1.2e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PVD36993.1 - 1.9e-05 24.6 0.1 3.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain LRR_4 PF12799.7 PVD36994.1 - 2.7e-39 132.5 35.9 8.5e-10 38.7 1.1 7.0 2 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD36994.1 - 5.3e-25 86.9 67.7 1.6e-07 30.9 3.8 6.6 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 PVD36994.1 - 1.4e-24 86.5 14.7 3e-10 39.9 4.5 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 PVD36994.1 - 1.5e-08 34.0 22.9 0.17 12.0 0.3 8.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 PVD36994.1 - 3e-06 27.0 21.7 8.5 7.4 0.6 8.7 8 3 0 8 8 8 5 Leucine Rich Repeat SSF PF00474.17 PVD36995.1 - 2.6e-131 438.2 17.3 4.2e-131 437.6 17.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family I-set PF07679.16 PVD36996.1 - 1.8e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD36996.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD36996.1 - 0.0035 17.9 0.0 0.0073 16.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain UL141 PF16758.5 PVD36996.1 - 0.0061 16.3 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Herpes-like virus membrane glycoprotein UL141 V-set PF07686.17 PVD36996.1 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD36996.1 - 0.024 15.0 0.1 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain UCH PF00443.29 PVD36997.1 - 4.7e-47 160.6 0.0 6.3e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 PVD36997.1 - 5.9e-25 86.8 0.0 4.3e-24 84.0 0.0 2.3 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 PVD36997.1 - 3.7e-24 84.2 0.1 1.6e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 PVD36997.1 - 3.4e-16 59.3 0.0 1.1e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PVD36997.1 - 2.3e-11 43.9 0.0 9.3e-07 28.7 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 PVD36997.1 - 0.0043 16.8 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBA_3 PF09288.10 PVD36997.1 - 0.15 11.9 0.0 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Pex14_N PF04695.13 PVD36999.1 - 5.5e-22 79.1 6.1 5.5e-22 79.1 6.1 3.4 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SlyX PF04102.12 PVD36999.1 - 0.041 14.5 0.3 0.041 14.5 0.3 2.2 2 0 0 2 2 2 0 SlyX ABC_tran_CTD PF16326.5 PVD36999.1 - 0.047 13.9 0.9 0.047 13.9 0.9 2.7 4 0 0 4 4 4 0 ABC transporter C-terminal domain DUF4407 PF14362.6 PVD36999.1 - 0.1 11.9 0.3 0.22 10.9 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 PVD37000.1 - 1.3e-12 47.9 8.8 2.6e-12 46.8 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PVD37000.1 - 4.8e-08 33.2 7.7 1.9e-07 31.3 7.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PVD37000.1 - 4.6e-07 29.6 8.8 4.6e-07 29.6 8.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD37000.1 - 1.9e-06 27.8 4.9 6.8e-06 26.0 4.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD37000.1 - 3e-06 27.0 6.7 6.3e-06 26.0 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD37000.1 - 6.2e-06 26.1 7.1 1.5e-05 24.8 7.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD37000.1 - 1.7e-05 24.6 7.8 4e-05 23.4 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PVD37000.1 - 2.7e-05 23.8 8.4 6.5e-05 22.6 8.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 PVD37000.1 - 7.3e-05 22.5 7.7 0.00014 21.6 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD37000.1 - 0.0004 20.4 4.2 0.00083 19.4 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger GOLGA2L5 PF15070.6 PVD37000.1 - 0.0006 18.6 11.1 0.0006 18.6 11.1 2.1 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 DUF1664 PF07889.12 PVD37000.1 - 0.0032 17.5 1.9 0.0032 17.5 1.9 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) Zn_ribbon_17 PF17120.5 PVD37000.1 - 0.0058 16.2 7.4 0.011 15.4 7.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PVD37000.1 - 0.04 14.1 5.7 0.12 12.6 5.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Spc7 PF08317.11 PVD37000.1 - 0.14 11.0 39.6 0.85 8.4 12.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 PVD37000.1 - 0.34 11.0 39.7 0.14 12.3 9.2 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 PVD37000.1 - 0.41 9.2 23.5 0.67 8.5 23.5 1.3 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.6 PVD37000.1 - 0.45 10.3 6.6 0.94 9.3 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GAS PF13851.6 PVD37000.1 - 0.66 9.3 44.0 0.08 12.3 11.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RINGv PF12906.7 PVD37000.1 - 0.68 10.1 6.8 1.9 8.7 6.8 1.8 1 0 0 1 1 1 0 RING-variant domain Lebercilin PF15619.6 PVD37000.1 - 1.9 8.1 42.0 0.44 10.2 9.6 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-C3HC4_4 PF15227.6 PVD37000.1 - 2.3 8.4 5.4 6.9 6.9 5.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING LPP PF04728.13 PVD37000.1 - 2.7 8.5 13.8 0.14 12.6 0.8 3.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper ADIP PF11559.8 PVD37000.1 - 2.9 7.9 41.3 0.38 10.8 11.3 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sulfatase_C PF14707.6 PVD37000.1 - 4.7 8.0 8.7 6.7 7.5 0.3 3.2 1 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Rootletin PF15035.6 PVD37000.1 - 5.3 7.0 32.6 1.8e+02 2.0 32.5 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.12 PVD37000.1 - 5.4 7.0 22.5 1.8 8.6 1.7 3.3 2 1 1 3 3 3 0 Laminin Domain II CdvA PF18822.1 PVD37000.1 - 5.5 6.8 25.8 1.4 8.7 1.3 3.6 2 1 1 3 3 3 0 CdvA-like coiled-coil domain PHD PF00628.29 PVD37000.1 - 6.6 6.7 9.0 15 5.6 9.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 PVD37000.1 - 6.9 7.1 7.7 15 6.0 7.7 1.6 1 0 0 1 1 1 0 RING-like domain DUF3584 PF12128.8 PVD37000.1 - 7.7 3.9 30.5 13 3.2 30.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 PVD37000.1 - 9 6.7 34.7 4.3 7.7 6.7 2.3 1 1 1 2 2 2 0 Fez1 cNMP_binding PF00027.29 PVD37001.1 - 5.8e-16 58.3 0.0 1.7e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain zf-C2H2 PF00096.26 PVD37002.1 - 3.2e-14 52.5 48.7 0.00031 21.0 2.1 7.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD37002.1 - 6.3e-14 51.7 38.9 0.00051 20.4 1.9 7.9 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD37002.1 - 7.5e-12 45.0 44.4 0.00083 20.0 1.3 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 PVD37002.1 - 6.1e-11 42.3 43.2 0.0012 19.2 0.3 7.7 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD37002.1 - 0.00013 22.2 35.7 0.011 16.1 0.5 7.1 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 PVD37002.1 - 0.041 13.4 8.3 0.45 10.1 0.1 3.3 3 1 1 4 4 4 0 Zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PVD37002.1 - 0.057 13.4 31.1 0.8 9.8 0.2 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PVD37002.1 - 0.094 13.0 21.6 0.2 12.0 1.3 4.1 2 2 2 4 4 4 0 C2H2-type zinc ribbon Actin_micro PF17003.5 PVD37002.1 - 0.17 11.1 15.7 0.34 10.0 0.1 4.1 2 1 3 5 5 5 0 Putative actin-like family zf-C2H2_2 PF12756.7 PVD37002.1 - 0.32 11.4 32.6 14 6.0 10.4 5.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PVD37002.1 - 1.3 9.2 17.3 14 5.9 0.5 4.6 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 PVD37002.1 - 2.1 9.1 15.5 10 6.9 0.4 3.7 3 1 0 3 3 3 0 zinc-ribbon family PHD_4 PF16866.5 PVD37002.1 - 5.2 7.2 13.7 3.2 7.9 0.3 3.6 3 0 0 3 3 3 0 PHD-finger zf_C2H2_ZHX PF18387.1 PVD37002.1 - 5.6 6.7 16.0 0.76 9.5 2.2 3.6 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain UreF PF01730.16 PVD37003.1 - 9.5e-23 81.2 0.1 1.1e-22 81.0 0.1 1.1 1 0 0 1 1 1 1 UreF Phage_holin_4_1 PF05105.12 PVD37003.1 - 0.05 13.7 0.3 0.19 11.9 0.0 2.0 2 1 0 2 2 2 0 Bacteriophage holin family RUN PF02759.19 PVD37004.1 - 3.1e-16 59.6 0.3 8.6e-16 58.1 0.3 1.8 1 0 0 1 1 1 1 RUN domain PH PF00169.29 PVD37004.1 - 3.3e-14 53.3 0.2 1.1e-10 41.9 0.0 3.3 3 0 0 3 3 3 2 PH domain PH_9 PF15410.6 PVD37004.1 - 0.037 14.4 0.1 0.68 10.3 0.0 2.9 4 0 0 4 4 4 0 Pleckstrin homology domain AA_permease_2 PF13520.6 PVD37005.1 - 8.9e-49 166.4 55.5 1.5e-47 162.4 40.3 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 PVD37005.1 - 5.7e-40 137.3 37.3 5.7e-40 137.3 37.3 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 PVD37005.1 - 7.1e-20 70.8 12.8 7.1e-20 70.8 12.8 4.4 5 1 0 5 5 5 1 C-terminus of AA_permease 7tm_1 PF00001.21 PVD37006.1 - 3.2e-22 79.1 23.7 2.1e-17 63.3 10.9 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 PVD37006.1 - 0.00032 20.5 7.0 0.00032 20.5 7.0 3.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 CoA_binding_3 PF13727.6 PVD37006.1 - 0.037 14.1 0.5 0.037 14.1 0.5 2.4 2 0 0 2 2 2 0 CoA-binding domain Synaptobrevin PF00957.21 PVD37006.1 - 0.14 12.0 2.3 7.1 6.5 0.0 3.0 2 0 0 2 2 2 0 Synaptobrevin Orf78 PF06024.12 PVD37006.1 - 4.2 7.7 12.8 0.37 11.1 1.3 3.7 4 0 0 4 4 4 0 Orf78 (ac78) TDP43_N PF18694.1 PVD37008.1 - 1e-32 111.8 0.0 1.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 PVD37008.1 - 3.1e-27 94.2 0.0 2.7e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD37008.1 - 4.9e-06 26.6 0.1 0.12 12.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD37008.1 - 0.00013 21.9 0.0 0.047 13.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 PVD37008.1 - 0.00016 21.5 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 RL domain DUF4651 PF15513.6 PVD37008.1 - 0.0086 15.9 0.0 7.4 6.5 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4651) RRM_3 PF08777.11 PVD37008.1 - 0.039 14.0 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif XPG_I_2 PF12813.7 PVD37009.1 - 0.0002 20.9 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 PVD37009.1 - 0.0021 18.4 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc_N PF02739.16 PVD37009.1 - 0.037 13.9 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Acatn PF13000.7 PVD37010.1 - 4.9e-119 398.3 21.1 4.2e-75 253.3 8.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Cation_efflux PF01545.21 PVD37011.1 - 2.5e-33 115.5 5.8 3.5e-33 115.0 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PVD37011.1 - 1.6e-09 37.7 0.1 3.1e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2339 PF10101.9 PVD37011.1 - 0.014 14.0 0.9 0.018 13.6 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) ZT_dimer PF16916.5 PVD37012.1 - 1.4e-09 38.0 0.1 3e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 PVD37012.1 - 1.7e-05 24.6 10.2 0.4 10.4 0.3 3.2 2 1 1 3 3 3 3 Cation efflux family Bac_transf PF02397.16 PVD37012.1 - 0.12 11.9 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial sugar transferase SH2 PF00017.24 PVD37013.1 - 2.8e-53 177.9 0.1 2e-25 88.7 0.0 2.9 3 0 0 3 3 3 2 SH2 domain Y_phosphatase PF00102.27 PVD37013.1 - 8.9e-41 140.0 7.7 6.2e-34 117.6 1.4 2.4 1 1 1 2 2 2 2 Protein-tyrosine phosphatase ATPgrasp_N PF18130.1 PVD37014.1 - 3.9e-12 46.6 0.0 2.7e-11 43.9 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 PVD37014.1 - 3.3e-11 43.0 0.0 1.5e-10 40.9 0.0 2.2 1 1 1 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PVD37014.1 - 3.3e-09 36.6 0.6 5.4e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PVD37014.1 - 5.7e-07 29.7 0.0 2.8e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 PVD37014.1 - 0.00035 20.4 0.0 0.013 15.3 0.0 2.4 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.21 PVD37014.1 - 0.0021 17.6 0.1 0.0048 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.17 PVD37014.1 - 0.0029 17.2 0.0 0.074 12.5 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 PVD37014.1 - 0.0036 16.9 0.1 1.6 8.3 0.0 3.2 3 0 0 3 3 3 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 PVD37014.1 - 0.0066 16.0 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus M20_dimer PF07687.14 PVD37014.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain NAD_binding_7 PF13241.6 PVD37014.1 - 0.013 15.9 0.4 1.3 9.5 0.4 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 PVD37014.1 - 0.081 12.3 0.2 3.6 6.9 0.1 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RVT_1 PF00078.27 PVD37015.1 - 4.8e-07 29.5 0.1 8.8e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HH_signal PF01085.18 PVD37016.1 - 3.4e-16 59.3 0.0 1.6e-06 27.9 0.0 3.0 3 0 0 3 3 3 2 Hedgehog amino-terminal signalling domain Big_9 PF17963.1 PVD37017.1 - 1.1e-09 38.9 0.1 1.1e-09 38.9 0.1 5.4 5 1 0 5 5 5 1 Bacterial Ig domain PAN_1 PF00024.26 PVD37017.1 - 3.2e-05 23.8 0.7 0.00014 21.7 0.7 2.1 1 0 0 1 1 1 1 PAN domain Cadherin_4 PF17803.1 PVD37017.1 - 0.00054 20.5 0.0 0.00054 20.5 0.0 5.2 4 0 0 4 4 4 1 Bacterial cadherin-like domain Big_3_2 PF12245.8 PVD37017.1 - 0.015 15.6 2.8 5.5 7.3 0.1 4.1 3 0 0 3 3 3 0 Bacterial Ig-like domain HEAT_2 PF13646.6 PVD37017.1 - 0.025 15.0 0.7 1.3 9.5 0.2 2.6 2 0 0 2 2 2 0 HEAT repeats Cadherin_5 PF17892.1 PVD37017.1 - 0.078 13.0 2.1 2.2 8.3 0.0 3.6 4 0 0 4 4 4 0 Cadherin-like domain Big_3_3 PF13750.6 PVD37017.1 - 0.11 12.1 7.9 2.4 7.8 0.0 5.0 5 1 0 5 5 5 0 Bacterial Ig-like domain (group 3) Mis12 PF05859.12 PVD37017.1 - 0.13 12.3 0.5 3.2 7.8 0.1 2.8 2 0 0 2 2 2 0 Mis12 protein DUF2369 PF10179.9 PVD37017.1 - 1.4 9.3 8.4 6.6 7.2 0.1 4.1 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Syntaxin_2 PF14523.6 PVD37017.1 - 2.1 8.7 4.4 6.3 7.2 0.4 3.7 3 1 1 4 4 4 0 Syntaxin-like protein Glyco_transf_8 PF01501.20 PVD37018.1 - 3.2e-07 30.2 0.1 4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 PVD37018.1 - 0.0054 16.2 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Glucosyltransferase 24 zf-H2C2_5 PF13909.6 PVD37019.1 - 0.00071 19.3 3.5 0.00071 19.3 3.5 3.6 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PVD37019.1 - 0.0042 17.4 3.3 0.0042 17.4 3.3 4.8 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 PVD37019.1 - 0.0047 17.3 32.3 0.077 13.5 3.5 6.8 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 PVD37019.1 - 0.012 15.9 0.4 0.012 15.9 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD37019.1 - 0.074 13.4 0.1 0.074 13.4 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Chorion_1 PF01723.16 PVD37019.1 - 0.14 12.1 0.7 0.29 11.1 0.7 1.4 1 0 0 1 1 1 0 Chorion protein zf-met PF12874.7 PVD37019.1 - 0.62 10.5 6.8 1.1 9.7 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 PVD37019.1 - 0.66 9.6 10.6 0.33 10.6 0.1 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 PVD37019.1 - 0.7 10.9 29.2 26 6.0 2.1 6.8 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD37019.1 - 2.3 8.3 7.1 13 5.9 0.4 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Glutaredoxin PF00462.24 PVD37021.1 - 4.6e-20 71.6 0.0 6.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 PVD37021.1 - 0.00019 21.8 0.1 0.00026 21.4 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 PVD37021.1 - 0.00079 19.8 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 PVD37021.1 - 0.028 14.5 0.1 0.069 13.2 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 PVD37021.1 - 0.087 13.0 0.5 4.2 7.5 0.7 2.1 1 1 1 2 2 2 0 Thioredoxin Ras PF00071.22 PVD37022.1 - 3.2e-49 166.7 0.2 3.2e-49 166.7 0.2 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PVD37022.1 - 1.7e-32 112.1 0.1 5.1e-32 110.6 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD37022.1 - 6.6e-13 48.5 0.0 6.6e-13 48.5 0.0 2.7 2 1 1 3 3 3 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD37022.1 - 2e-06 27.9 0.0 2e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD37022.1 - 0.0013 18.3 0.1 0.0013 18.3 0.1 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PVD37022.1 - 0.0015 18.5 0.4 0.087 12.7 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 PVD37022.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.4 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) V_ATPase_I PF01496.19 PVD37022.1 - 2 6.2 19.6 3.6 5.4 19.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF-hand_7 PF13499.6 PVD37023.1 - 0.00017 22.0 0.1 0.00034 21.0 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD37023.1 - 0.0057 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 PVD37023.1 - 0.018 14.9 0.1 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair Sir1 PF11603.8 PVD37023.1 - 0.047 14.2 0.2 0.19 12.2 0.1 1.9 1 1 1 2 2 2 0 Regulatory protein Sir1 EF-hand_1 PF00036.32 PVD37023.1 - 0.079 12.5 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 EF hand EMP24_GP25L PF01105.24 PVD37024.1 - 1.1e-06 28.7 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CENP-F_C_Rb_bdg PF10490.9 PVD37024.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 IgGFc_binding PF17517.2 PVD37026.1 - 2.8e-46 158.1 7.2 2.8e-46 158.1 7.2 1.8 1 1 1 2 2 2 1 IgGFc binding protein Cu-binding_MopE PF11617.8 PVD37026.1 - 0.001 19.2 1.1 0.0024 18.0 1.1 1.7 1 0 0 1 1 1 1 Putative metal-binding motif eIF-6 PF01912.18 PVD37027.1 - 0.07 12.5 0.0 0.074 12.4 0.0 1.0 1 0 0 1 1 1 0 eIF-6 family 7TM_GPCR_Srw PF10324.9 PVD37028.1 - 1.3e-41 143.0 14.2 4.5e-41 141.2 14.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD37028.1 - 4.3e-19 68.9 6.8 6.3e-19 68.3 6.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 PVD37028.1 - 3.6e-05 23.0 10.6 0.00011 21.4 10.6 1.6 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srx PF10328.9 PVD37028.1 - 0.0001 22.0 14.3 0.00019 21.2 14.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0542 PF15086.6 PVD37028.1 - 2.3 8.2 5.3 0.49 10.4 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 7TM_GPCR_Srw PF10324.9 PVD37029.1 - 1e-34 120.3 3.6 1.3e-34 120.0 3.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD37029.1 - 2.7e-17 63.0 7.0 3.4e-17 62.6 7.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 PVD37029.1 - 6.8e-05 22.1 4.7 0.00068 18.8 4.7 2.0 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srx PF10328.9 PVD37029.1 - 0.0047 16.6 14.7 0.0047 16.6 14.7 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx FtsJ PF01728.19 PVD37030.1 - 9.7e-59 198.4 0.0 3.8e-58 196.5 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cu2_monooxygen PF01082.20 PVD37031.1 - 1.8e-23 83.2 1.5 2.6e-20 73.0 0.5 2.6 1 1 1 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 PVD37031.1 - 2.3e-20 72.7 0.1 2.3e-20 72.7 0.1 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain SPOC PF07744.13 PVD37032.1 - 1.2e-30 106.4 0.0 3e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 PVD37032.1 - 2.4e-30 104.1 2.0 1.8e-12 46.9 0.1 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD37032.1 - 8.4e-05 22.2 0.1 0.18 11.4 0.0 3.6 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PVD37032.1 - 0.0067 16.5 0.1 0.66 10.1 0.0 3.4 2 0 0 2 2 2 1 Limkain b1 Amidohydro_3 PF07969.11 PVD37033.1 - 3e-05 23.7 0.0 3.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PVD37033.1 - 0.0055 16.1 1.2 0.018 14.4 1.2 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PVD37034.1 - 2.1e-06 27.3 1.0 3.4e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 PVD37034.1 - 2.3e-06 27.4 0.0 4.3e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family CG-1 PF03859.16 PVD37036.1 - 1.6e-41 140.7 0.5 1.6e-41 140.7 0.5 2.1 2 1 0 2 2 2 1 CG-1 domain Ank_2 PF12796.7 PVD37036.1 - 0.00038 21.0 0.1 0.0012 19.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 PVD37036.1 - 0.0017 18.4 0.0 0.027 14.5 0.0 2.9 2 0 0 2 2 2 1 IPT/TIG domain IQ PF00612.27 PVD37036.1 - 0.0057 16.3 23.5 0.049 13.4 1.3 4.8 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_5 PF13857.6 PVD37036.1 - 0.008 16.5 0.2 0.021 15.1 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37036.1 - 0.055 14.0 1.0 20 6.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF3395 PF11875.8 PVD37037.1 - 1.9e-48 164.3 0.6 5.3e-48 162.9 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PVD37037.1 - 6.1e-18 64.7 2.5 6.1e-18 64.7 2.5 2.0 2 0 0 2 2 2 1 DnaJ domain DUF5305 PF17231.2 PVD37037.1 - 0.037 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Pox_ser-thr_kin PF05445.11 PVD37038.1 - 0.068 12.1 0.5 0.095 11.6 0.5 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase dsRBD2 PF17842.1 PVD37038.1 - 2.2 8.5 14.6 0.066 13.4 4.6 2.2 1 1 1 2 2 2 0 Double-stranded RNA binding domain 2 GEN1_C PF18380.1 PVD37038.1 - 4.1 8.4 11.5 5.5 7.9 0.6 2.6 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Thg1C PF14413.6 PVD37038.1 - 9.3 6.4 14.2 0.9 9.7 5.9 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain ABC_membrane PF00664.23 PVD37039.1 - 4.1e-68 230.0 25.1 5.1e-41 141.1 17.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD37039.1 - 7.2e-51 172.3 0.1 1.3e-27 97.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PVD37039.1 - 3.6e-08 33.1 2.3 0.071 12.5 0.6 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD37039.1 - 1.1e-06 29.2 0.2 0.0067 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD37039.1 - 2.1e-06 27.8 1.5 0.062 13.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD37039.1 - 1.8e-05 24.7 2.4 0.053 13.4 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PVD37039.1 - 4.7e-05 23.1 1.6 0.071 12.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PVD37039.1 - 6.7e-05 22.8 2.1 3.1 7.5 0.1 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 PVD37039.1 - 0.0011 19.0 1.6 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 PVD37039.1 - 0.011 16.2 0.7 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PVD37039.1 - 0.017 15.2 5.8 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 PVD37039.1 - 0.03 14.6 0.3 4.8 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PVD37039.1 - 0.038 13.3 0.7 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 PVD37039.1 - 0.063 12.9 0.6 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PVD37039.1 - 0.064 13.0 0.2 11 5.7 0.1 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 PVD37039.1 - 0.073 12.1 1.4 0.69 8.9 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 PVD37039.1 - 0.093 11.6 1.5 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 PVD37039.1 - 0.097 11.8 0.6 11 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 PVD37039.1 - 0.12 12.1 0.9 4 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 PVD37039.1 - 0.12 12.6 1.6 16 5.8 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 PVD37039.1 - 0.14 11.6 0.5 12 5.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 PVD37039.1 - 0.27 10.9 1.3 2.2 7.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 PVD37039.1 - 0.61 9.7 2.5 0.76 9.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3165 PF11364.8 PVD37039.1 - 0.86 10.0 12.3 0.11 12.8 0.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) Ctr PF04145.15 PVD37039.1 - 0.87 10.2 4.6 1.2 9.7 2.4 2.4 2 1 0 2 2 2 0 Ctr copper transporter family fn3 PF00041.21 PVD37041.1 - 0.093 13.1 0.1 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Fibronectin type III domain Anoctamin PF04547.12 PVD37042.1 - 4.9e-05 22.4 2.1 7.2e-05 21.8 2.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel DDOST_48kD PF03345.14 PVD37043.1 - 2.8e-132 441.5 0.1 4.8e-132 440.7 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta TMC PF07810.13 PVD37043.1 - 2.7e-28 98.8 0.8 8.1e-28 97.2 0.8 1.9 1 0 0 1 1 1 1 TMC domain Ank_2 PF12796.7 PVD37044.1 - 3.2e-41 139.8 4.9 3.1e-16 59.7 0.6 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37044.1 - 2.6e-25 88.4 3.4 5.5e-08 33.2 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD37044.1 - 1.8e-24 85.0 4.3 1.6e-07 31.5 0.2 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PVD37044.1 - 4.7e-23 81.0 3.5 1e-11 44.8 0.5 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37044.1 - 4.5e-20 69.6 4.0 0.00019 21.6 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Kazal_2 PF07648.15 PVD37045.1 - 2e-72 239.1 146.0 4.4e-11 42.7 5.9 12.3 12 1 0 12 12 12 9 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.23 PVD37045.1 - 2.3e-67 225.2 0.4 2.1e-23 83.0 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 PVD37045.1 - 7e-64 214.1 1.9 3e-22 79.5 0.1 3.2 3 0 0 3 3 3 3 Laminin G domain Kazal_1 PF00050.21 PVD37045.1 - 8.1e-52 173.0 127.9 1.1e-09 38.2 10.1 10.5 9 1 0 9 9 9 9 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 PVD37045.1 - 2.4e-16 59.6 29.6 7.2e-10 38.9 10.9 16.6 13 5 4 17 17 17 3 Laminin EGF domain Laminin_G_3 PF13385.6 PVD37045.1 - 3.4e-14 53.3 0.1 2.3e-05 24.6 0.1 3.2 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD37045.1 - 9.3e-14 51.4 43.8 3.1e-07 30.5 7.0 16.6 17 0 0 17 17 17 4 EGF-like domain cEGF PF12662.7 PVD37045.1 - 0.093 12.7 0.1 0.093 12.7 0.1 8.7 7 1 0 7 7 7 0 Complement Clr-like EGF-like DUF1971 PF09313.11 PVD37045.1 - 0.14 12.2 0.0 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Mg-por_mtran_C PF07109.11 PVD37047.1 - 0.17 12.2 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus NtA PF03146.15 PVD37048.1 - 1.4e-34 118.2 0.2 1.9e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 Agrin NtA domain Pkinase_Tyr PF07714.17 PVD37049.1 - 2.8e-39 135.0 0.0 4.8e-39 134.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37049.1 - 4e-27 95.2 0.0 6.9e-27 94.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Insulin_TMD PF17870.1 PVD37049.1 - 0.041 13.9 0.3 0.091 12.8 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5326 PF17260.2 PVD37049.1 - 0.24 11.5 1.6 0.49 10.6 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) FXa_inhibition PF14670.6 PVD37050.1 - 1.6e-48 162.6 147.1 1.2e-09 38.3 11.8 35.9 14 4 14 28 28 28 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 PVD37050.1 - 1.7e-30 104.5 60.0 3.3e-08 33.3 0.9 36.1 38 4 1 39 39 39 9 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD37050.1 - 1.6e-22 79.4 87.9 1.3e-08 34.9 7.4 33.6 21 9 12 33 33 33 6 Calcium-binding EGF domain Laminin_EGF PF00053.24 PVD37050.1 - 5.1e-22 77.8 611.8 0.015 15.4 14.7 34.2 6 4 29 35 35 35 19 Laminin EGF domain EGF_3 PF12947.7 PVD37050.1 - 9.8e-05 22.5 25.9 0.00085 19.5 8.9 32.9 30 4 1 31 31 31 5 EGF domain EGF_2 PF07974.13 PVD37050.1 - 0.00022 21.5 11.8 0.00022 21.5 11.8 45.8 32 17 10 42 42 42 14 EGF-like domain EGF PF00008.27 PVD37050.1 - 0.0061 16.8 8.1 0.0061 16.8 8.1 40.6 42 2 1 43 43 43 18 EGF-like domain hEGF PF12661.7 PVD37050.1 - 0.0065 17.1 28.0 0.0086 16.7 4.5 40.3 38 4 0 38 38 38 18 Human growth factor-like EGF Peptidase_M13_N PF05649.13 PVD37052.1 - 1.1e-120 403.8 0.4 1.5e-120 403.4 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PVD37052.1 - 1.9e-59 200.7 0.3 4.9e-59 199.4 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M13 Cwf_Cwc_15 PF04889.12 PVD37055.1 - 0.0018 18.0 6.9 0.0018 18.0 6.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PVD37055.1 - 0.098 12.0 12.7 0.098 12.0 12.7 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 PVD37055.1 - 0.13 10.5 1.9 0.11 10.8 1.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 PVD37055.1 - 0.24 10.5 16.4 0.25 10.4 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 PVD37055.1 - 0.31 11.0 4.4 0.33 11.0 4.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal GCIP PF13324.6 PVD37055.1 - 0.38 10.3 3.7 0.34 10.5 3.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 PVD37055.1 - 0.49 10.3 4.1 0.48 10.3 4.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 PVD37055.1 - 0.51 10.4 3.8 0.41 10.7 3.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2076 PF09849.9 PVD37055.1 - 0.59 10.1 4.6 0.5 10.4 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRN3 PF05327.11 PVD37055.1 - 1.6 7.2 5.1 1.6 7.2 5.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 PVD37055.1 - 2.3 7.9 4.0 2.8 7.6 4.0 1.2 1 0 0 1 1 1 0 FAM176 family 7TM_GPCR_Srw PF10324.9 PVD37056.1 - 7.1e-19 68.2 5.9 1.7e-18 67.0 5.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Flot PF15975.5 PVD37056.1 - 0.046 13.9 0.0 0.072 13.3 0.0 1.2 1 0 0 1 1 1 0 Flotillin 7tm_1 PF00001.21 PVD37056.1 - 0.054 12.8 6.5 0.44 9.8 5.8 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD37057.1 - 2.4e-22 79.7 13.1 2.8e-22 79.4 13.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD37057.1 - 9.2e-08 31.7 5.8 1.2e-07 31.4 5.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2116 PF09889.9 PVD37057.1 - 0.18 11.8 0.9 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3382 PF11862.8 PVD37057.1 - 0.26 11.6 1.9 0.47 10.8 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) 7TM_GPCR_Srw PF10324.9 PVD37058.1 - 0.00027 20.4 0.4 0.00032 20.1 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw HTH_Tnp_Tc5 PF03221.16 PVD37059.1 - 0.00045 20.2 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Aldo_ket_red PF00248.21 PVD37059.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family HTH_23 PF13384.6 PVD37059.1 - 0.018 14.8 0.2 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain TP2 PF01254.18 PVD37059.1 - 0.043 14.4 0.2 0.068 13.8 0.1 1.4 1 1 0 1 1 1 0 Nuclear transition protein 2 HTH_Tnp_1 PF01527.20 PVD37059.1 - 0.049 13.9 0.5 0.19 12.0 0.1 2.2 2 1 1 3 3 3 0 Transposase MASE1 PF05231.14 PVD37060.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 MASE1 FAD-oxidase_C PF02913.19 PVD37061.1 - 5.2e-51 173.7 0.0 3e-50 171.2 0.0 2.2 2 1 1 3 3 3 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PVD37061.1 - 4.5e-37 126.9 0.2 7.2e-37 126.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GLTP PF08718.11 PVD37061.1 - 6.8e-33 114.1 0.3 1.4e-32 113.1 0.3 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF3677 PF12432.8 PVD37061.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Ssl1 PF04056.14 PVD37062.1 - 2e-36 125.6 0.1 3.3e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 PVD37062.1 - 8.6e-11 42.4 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Dynamin_N PF00350.23 PVD37063.1 - 1.3e-37 129.5 0.2 1.3e-37 129.5 0.2 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PVD37063.1 - 6.6e-05 23.0 0.0 0.0005 20.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD37063.1 - 0.00021 20.9 0.1 0.022 14.3 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 PVD37063.1 - 0.005 17.0 0.0 0.65 10.2 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PVD37063.1 - 0.0065 15.8 4.2 0.01 15.2 0.1 3.0 3 0 0 3 3 3 1 AIG1 family DUF1593 PF07632.11 PVD37063.1 - 0.0081 15.6 3.4 0.01 15.3 0.1 2.9 4 1 0 4 4 4 1 Protein of unknown function (DUF1593) DUF4268 PF14088.6 PVD37063.1 - 0.0088 15.9 1.6 0.0088 15.9 1.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4268) AAA_16 PF13191.6 PVD37063.1 - 0.06 13.7 0.1 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 PVD37063.1 - 0.33 11.2 5.2 2.8 8.2 0.0 4.1 4 1 0 5 5 5 0 AAA domain AAA_15 PF13175.6 PVD37063.1 - 0.54 9.9 0.0 0.54 9.9 0.0 4.4 2 2 1 3 3 3 0 AAA ATPase domain Mlf1IP PF10248.9 PVD37064.1 - 1.3e-60 204.3 10.3 1.8e-60 203.9 10.3 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Nup_retrotrp_bd PF10599.9 PVD37064.1 - 0.035 14.8 2.3 0.071 13.8 2.3 1.5 1 0 0 1 1 1 0 Retro-transposon transporting motif Cyclin_N PF00134.23 PVD37065.1 - 5.2e-14 52.1 0.5 3.4e-10 39.7 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 PVD37065.1 - 0.0026 18.1 0.0 0.0091 16.4 0.0 2.0 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 PVD37065.1 - 0.0035 17.4 0.2 0.0035 17.4 0.2 3.7 3 2 0 4 4 4 1 Cyclin, C-terminal domain TFIIB_C_1 PF18542.1 PVD37065.1 - 0.0053 16.7 0.2 0.42 10.7 0.1 2.5 2 0 0 2 2 2 1 Transcription factor IIB C-terminal module 1 TFIIB PF00382.19 PVD37065.1 - 0.0088 16.1 0.2 3.2 7.8 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat PHD PF00628.29 PVD37066.1 - 0.0076 16.1 15.4 0.18 11.7 4.4 3.8 3 0 0 3 3 3 2 PHD-finger Serglycin PF04360.12 PVD37071.1 - 0.14 12.1 2.4 0.13 12.2 1.1 1.6 2 0 0 2 2 2 0 Serglycin Birna_VP5 PF03042.14 PVD37072.1 - 0.0089 16.1 2.9 0.014 15.4 2.9 1.3 1 0 0 1 1 1 1 Birnavirus VP5 protein MarR_2 PF12802.7 PVD37072.1 - 0.059 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 MarR family DUF5466 PF17554.2 PVD37072.1 - 1.8 8.8 5.8 1.2 9.4 3.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5466) Noc2 PF03715.13 PVD37074.1 - 4e-120 400.6 9.5 9.2e-120 399.4 9.5 1.6 1 0 0 1 1 1 1 Noc2p family Thioredoxin_2 PF13098.6 PVD37074.1 - 0.0008 19.8 0.2 2.2 8.8 0.0 3.1 2 0 0 2 2 2 2 Thioredoxin-like domain DUF5058 PF16481.5 PVD37074.1 - 0.048 13.3 0.7 0.1 12.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Peptidase_M48_N PF16491.5 PVD37074.1 - 0.054 13.4 1.0 3.9 7.3 0.1 3.2 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices Questin_oxidase PF14027.6 PVD37074.1 - 7.1 6.1 0.0 7.1 6.1 0.0 3.7 4 1 0 4 4 4 0 Questin oxidase-like Pkinase_Tyr PF07714.17 PVD37084.1 - 1.3e-93 313.0 0.0 1.7e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37084.1 - 7.7e-43 146.7 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 PVD37084.1 - 4.8e-42 144.0 0.3 8.2e-42 143.3 0.3 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain EphA2_TM PF14575.6 PVD37084.1 - 3.2e-23 82.4 0.6 5.4e-23 81.7 0.0 1.8 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain fn3 PF00041.21 PVD37084.1 - 1.5e-22 79.7 3.0 5.7e-12 45.8 0.1 3.3 4 0 0 4 4 2 2 Fibronectin type III domain SAM_1 PF00536.30 PVD37084.1 - 1.6e-18 66.9 0.1 3.6e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD37084.1 - 5.3e-16 58.5 0.0 1.4e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ephrin_rec_like PF07699.13 PVD37084.1 - 9.6e-06 25.3 6.0 9.6e-06 25.3 6.0 2.7 1 1 1 2 2 2 1 Putative ephrin-receptor like DUF2369 PF10179.9 PVD37084.1 - 0.0031 17.8 0.9 0.0075 16.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) VSP PF03302.13 PVD37084.1 - 0.0037 16.2 5.6 0.0068 15.3 5.6 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Pur_ac_phosph_N PF16656.5 PVD37084.1 - 0.028 15.0 2.5 4.5 7.9 0.4 3.2 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 PVD37084.1 - 0.045 13.7 9.3 0.19 11.7 0.8 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 PVD37084.1 - 0.071 13.2 5.8 0.73 9.9 0.6 2.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 Kdo PF06293.14 PVD37084.1 - 0.22 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RANK_CRD_2 PF18278.1 PVD37084.1 - 0.63 10.2 3.6 4.2 7.6 0.4 2.6 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DUF4133 PF13571.6 PVD37084.1 - 0.76 10.1 2.6 6.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) IMS PF00817.20 PVD37086.1 - 1.7e-41 141.7 0.0 3.3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family PIG-P PF08510.12 PVD37086.1 - 4.9e-30 103.9 2.0 1e-29 102.9 2.0 1.5 1 0 0 1 1 1 1 PIG-P BRCT_2 PF16589.5 PVD37086.1 - 4e-14 52.8 0.0 9.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 PVD37086.1 - 1.3e-12 48.4 0.0 3.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 PVD37086.1 - 1.6e-10 41.2 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 PVD37086.1 - 1.8e-08 34.5 0.0 5.5e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain UBM PF14377.6 PVD37086.1 - 8.3e-07 28.2 4.3 0.33 10.4 0.0 3.7 3 0 0 3 3 3 3 Ubiquitin binding region PTCB-BRCT PF12738.7 PVD37086.1 - 1.1e-06 28.4 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 PVD37086.1 - 1.7e-06 28.0 0.0 9e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif REV1_C PF16727.5 PVD37086.1 - 4.7e-06 26.9 0.1 9.5e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain Cdd1 PF11731.8 PVD37086.1 - 0.0026 17.9 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus DUF1805 PF08827.11 PVD37086.1 - 0.06 13.7 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DPM2 PF07297.12 PVD37086.1 - 0.48 10.8 4.3 0.92 9.9 4.3 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Peptidase_C1 PF00112.23 PVD37087.1 - 9e-60 202.5 0.8 1.2e-59 202.0 0.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PVD37087.1 - 6.5e-14 52.1 0.6 9.8e-14 51.5 0.6 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PVD37087.1 - 9.5e-07 27.9 1.7 4.9e-05 22.3 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cation_efflux PF01545.21 PVD37088.1 - 7e-30 104.2 5.2 9.7e-30 103.8 5.2 1.1 1 0 0 1 1 1 1 Cation efflux family SNF PF00209.18 PVD37089.1 - 9.3e-181 602.0 37.3 1.2e-180 601.7 37.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Neuralized PF07177.12 PVD37090.1 - 2.2e-263 861.9 0.6 1e-44 152.1 0.0 6.1 6 0 0 6 6 6 6 Neuralized SPRY PF00622.28 PVD37090.1 - 1.2e-19 70.6 0.1 0.00042 20.4 0.0 6.0 6 1 0 6 6 6 5 SPRY domain DUF1353 PF07087.11 PVD37090.1 - 0.11 12.3 0.0 9.1 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1353) ING PF12998.7 PVD37091.1 - 6.4e-19 68.4 1.6 6.4e-19 68.4 1.6 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF1192 PF06698.11 PVD37091.1 - 0.028 14.5 0.8 7.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 PVD37091.1 - 0.34 10.2 5.7 0.45 9.8 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GATase PF00117.28 PVD37093.1 - 9.5e-38 129.9 0.0 2e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 PVD37093.1 - 2.1e-19 69.4 0.2 7.9e-11 41.9 0.0 3.6 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 PVD37093.1 - 7.3e-11 41.6 0.0 6.9e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 PVD37093.1 - 2.2e-10 40.7 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 PVD37093.1 - 4.7e-07 29.5 0.0 2.1e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 PVD37093.1 - 9.9e-06 24.6 0.1 4.7e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 PVD37093.1 - 9.6e-05 22.2 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 PVD37093.1 - 0.00055 19.6 0.2 0.0013 18.3 0.2 1.7 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 PVD37093.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 PVD37093.1 - 0.0019 18.2 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 PVD37093.1 - 0.002 17.9 0.1 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 PP-loop family GATase_3 PF07685.14 PVD37093.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PseudoU_synth_1 PF01416.20 PVD37094.1 - 1.7e-20 73.5 0.0 3.2e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase SCO1-SenC PF02630.14 PVD37095.1 - 3.1e-48 163.1 0.0 6.5e-48 162.0 0.0 1.6 1 0 0 1 1 1 1 SCO1/SenC Helicase_C PF00271.31 PVD37095.1 - 2.2e-15 56.9 0.1 5.9e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PVD37095.1 - 6.3e-15 55.3 0.0 1.7e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PVD37095.1 - 9.5e-15 54.8 0.0 9.5e-15 54.8 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.29 PVD37095.1 - 2.1e-12 47.1 0.1 4.7e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PVD37095.1 - 1.2e-06 28.9 0.2 5.4e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AhpC-TSA PF00578.21 PVD37095.1 - 0.00079 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 PVD37095.1 - 0.0036 17.6 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like dsRBD2 PF17842.1 PVD37095.1 - 0.17 12.1 4.8 3.8 7.7 4.8 3.2 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 PVD37095.1 - 3.2 8.2 0.0 3.2 8.2 0.0 4.4 3 1 1 4 4 3 0 AAA domain DUF4050 PF13259.6 PVD37095.1 - 6.8 7.0 9.7 0.13 12.6 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4050) CARD PF00619.21 PVD37096.1 - 4.3e-10 39.5 0.2 9.1e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD37096.1 - 0.00011 22.2 0.4 0.00021 21.2 0.0 1.6 2 0 0 2 2 2 1 Caspase recruitment domain ABC_membrane PF00664.23 PVD37097.1 - 1.6e-77 260.9 22.8 1.8e-47 162.3 3.5 4.2 2 2 2 4 4 4 4 ABC transporter transmembrane region ABC_tran PF00005.27 PVD37097.1 - 1.8e-75 252.0 0.0 2.7e-38 131.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_ATPase PF09818.9 PVD37097.1 - 1.9e-11 43.5 0.9 0.00026 19.9 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class SMC_N PF02463.19 PVD37097.1 - 1.4e-09 37.8 0.0 0.0016 17.9 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PVD37097.1 - 1.5e-07 31.5 0.0 0.0078 16.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PVD37097.1 - 1.8e-07 31.7 1.8 0.01 16.2 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 PVD37097.1 - 1.2e-06 28.9 0.5 0.053 14.0 0.1 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD37097.1 - 2.4e-06 27.8 0.1 0.14 12.4 0.1 3.4 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PVD37097.1 - 7.4e-06 25.4 0.1 0.14 11.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 PVD37097.1 - 1.3e-05 24.9 0.2 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 PVD37097.1 - 3.7e-05 23.7 0.1 0.67 9.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PVD37097.1 - 5e-05 22.9 0.5 0.15 11.6 0.0 3.4 4 0 0 4 4 3 2 P-loop containing dynein motor region Rad17 PF03215.15 PVD37097.1 - 8.1e-05 22.6 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain DUF815 PF05673.13 PVD37097.1 - 0.00016 21.0 0.0 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 PVD37097.1 - 0.00021 21.6 0.0 0.49 10.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PVD37097.1 - 0.00022 21.0 0.3 0.52 10.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 PVD37097.1 - 0.00024 20.4 0.0 0.048 12.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 PVD37097.1 - 0.00033 20.6 0.0 0.14 12.0 0.0 3.6 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PVD37097.1 - 0.00039 20.2 0.0 0.042 13.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 PVD37097.1 - 0.0013 19.0 4.6 1.7 8.9 0.4 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 PVD37097.1 - 0.0016 18.1 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 PVD37097.1 - 0.003 18.1 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PVD37097.1 - 0.0068 16.5 2.6 8.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 PVD37097.1 - 0.0099 15.6 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PVD37097.1 - 0.012 15.6 0.2 0.91 9.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 PVD37097.1 - 0.016 14.8 0.4 3.8 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PVD37097.1 - 0.017 15.2 0.2 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD37097.1 - 0.019 14.1 0.1 2 7.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 PVD37097.1 - 0.02 14.6 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 PVD37097.1 - 0.023 14.8 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 PVD37097.1 - 0.026 14.9 0.0 7.2 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Synapsin_N PF10581.9 PVD37097.1 - 0.027 14.4 0.0 5 7.2 0.0 2.6 2 0 0 2 2 2 0 Synapsin N-terminal Viral_helicase1 PF01443.18 PVD37097.1 - 0.039 13.7 0.1 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 PVD37097.1 - 0.04 14.3 0.1 15 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PVD37097.1 - 0.1 12.5 0.0 20 5.0 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.6 PVD37097.1 - 0.49 10.9 2.7 3.8 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 PVD37098.1 - 2.2e-47 159.6 4.8 4e-18 65.8 0.1 5.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD37098.1 - 3.2e-41 138.8 10.3 8.4e-13 48.3 0.3 7.4 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD37098.1 - 9e-38 127.1 13.4 1.2e-06 28.7 0.1 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 PVD37098.1 - 2.1e-36 123.8 11.1 1.2e-10 41.7 0.0 6.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37098.1 - 3.2e-36 119.2 4.0 6.2e-07 29.2 0.1 8.8 9 0 0 9 9 9 6 Ankyrin repeat SH3_15 PF18346.1 PVD37098.1 - 2.5e-27 95.0 11.6 1.8e-17 63.4 0.8 3.7 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain PARP PF00644.20 PVD37098.1 - 4.9e-26 91.5 1.7 2.6e-25 89.2 0.2 2.7 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain MIB_HERC2 PF06701.13 PVD37098.1 - 1e-20 73.7 20.1 1.9e-11 44.0 1.9 4.1 5 1 0 5 5 5 2 Mib_herc2 ZZ PF00569.17 PVD37098.1 - 2.5e-07 30.4 13.8 7.8e-07 28.8 13.8 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_2 PF12796.7 PVD37099.1 - 2.8e-45 152.8 13.4 3.9e-14 53.0 0.2 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD37099.1 - 2.4e-39 132.9 7.0 7.3e-10 38.9 0.2 6.5 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD37099.1 - 5.8e-38 127.7 14.8 1.9e-06 28.0 0.3 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 PVD37099.1 - 6e-37 125.6 7.6 3.8e-10 40.1 0.1 6.7 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37099.1 - 1.7e-34 113.9 7.1 8.8e-05 22.6 0.0 8.9 8 1 0 8 8 8 7 Ankyrin repeat PARP PF00644.20 PVD37099.1 - 1.2e-25 90.3 0.4 1.4e-24 86.7 0.4 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SH3_15 PF18346.1 PVD37099.1 - 7.3e-23 80.7 6.2 1.1e-13 51.3 0.8 2.8 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain ZZ PF00569.17 PVD37099.1 - 2.8e-05 23.8 8.1 9.6e-05 22.1 8.1 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type MIB_HERC2 PF06701.13 PVD37099.1 - 0.0029 17.8 0.2 0.016 15.5 0.2 2.4 1 0 0 1 1 1 1 Mib_herc2 Asp-B-Hydro_N PF05279.11 PVD37099.1 - 0.023 14.8 0.1 0.023 14.8 0.1 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Shigella_OspC PF06128.11 PVD37099.1 - 0.026 14.3 1.6 5.4 6.7 1.2 2.9 2 1 0 2 2 2 0 Shigella flexneri OspC protein Phage_T7_Capsid PF05396.11 PVD37099.1 - 0.032 14.6 2.2 9.7 6.6 0.2 3.9 2 1 1 3 3 3 0 Phage T7 capsid assembly protein PIN_4 PF13638.6 PVD37099.1 - 0.23 11.8 2.6 0.2 12.0 0.8 1.8 2 0 0 2 2 2 0 PIN domain Endonuc-EcoRV PF09233.11 PVD37102.1 - 0.087 12.2 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRV 7tm_1 PF00001.21 PVD37104.1 - 1e-23 84.0 22.8 1.2e-18 67.4 10.1 2.7 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Synaptobrevin PF00957.21 PVD37104.1 - 0.11 12.3 0.2 0.11 12.3 0.2 3.0 3 0 0 3 3 3 0 Synaptobrevin Exo_endo_phos_2 PF14529.6 PVD37105.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_hydro_9 PF00759.19 PVD37106.1 - 1.2e-126 423.4 6.1 2.3e-126 422.6 6.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DcpS_C PF11969.8 PVD37106.1 - 6.4e-30 104.0 0.3 1.5e-29 102.8 0.3 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 PVD37106.1 - 1.3e-18 67.7 0.2 2.8e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal RNA_pol_Rpb2_5 PF04567.17 PVD37106.1 - 0.052 14.1 0.1 0.19 12.3 0.1 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 14-3-3 PF00244.20 PVD37107.1 - 1.5e-93 312.4 8.5 1.8e-93 312.1 8.5 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 PVD37107.1 - 0.007 16.6 0.6 0.023 15.0 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat CARD PF00619.21 PVD37108.1 - 3.3e-14 52.7 0.6 3.9e-14 52.5 0.6 1.1 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD37108.1 - 1.6e-05 24.8 0.4 1.8e-05 24.6 0.4 1.1 1 0 0 1 1 1 1 Caspase recruitment domain Peptidase_C14 PF00656.22 PVD37109.1 - 3.5e-44 151.6 0.0 6.9e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 PVD37109.1 - 9.3e-15 54.4 0.6 2e-14 53.3 0.6 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 PVD37109.1 - 0.00012 22.0 0.2 0.00044 20.2 0.2 2.0 1 0 0 1 1 1 1 Caspase recruitment domain IPK PF03770.16 PVD37109.1 - 0.038 13.8 0.1 0.095 12.5 0.1 1.6 1 0 0 1 1 1 0 Inositol polyphosphate kinase WD40 PF00400.32 PVD37110.1 - 7.2e-40 134.3 20.2 8.1e-07 29.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD37110.1 - 2.8e-14 53.2 0.0 0.021 15.1 0.0 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD37110.1 - 0.00012 21.6 0.0 0.0086 15.4 0.0 2.7 1 1 2 3 3 3 2 WD40-like domain eIF2A PF08662.11 PVD37110.1 - 0.00014 21.8 0.0 0.57 10.0 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD37110.1 - 0.0078 15.2 0.6 20 4.0 0.1 3.8 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFR_dimer PF04253.15 PVD37111.1 - 5e-16 58.9 0.1 9.8e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 PVD37111.1 - 1.7e-12 47.4 0.0 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD37111.1 - 1e-09 38.3 0.0 2.9e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 PA domain DUF4731 PF15875.5 PVD37111.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Ank_2 PF12796.7 PVD37112.1 - 3.1e-46 155.9 15.3 9.7e-14 51.7 0.6 4.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD37112.1 - 2e-29 100.7 4.7 3.8e-06 27.1 0.1 6.7 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PVD37112.1 - 5.1e-29 100.3 1.0 3.9e-09 36.9 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37112.1 - 4.5e-28 96.9 3.9 2.2e-09 37.4 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37112.1 - 9.9e-22 74.7 1.0 0.00099 19.4 0.1 6.8 7 0 0 7 7 7 4 Ankyrin repeat SH3_15 PF18346.1 PVD37112.1 - 4.5e-18 65.3 0.0 1.1e-12 48.1 0.1 2.5 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 PVD37112.1 - 6.6e-06 25.9 10.7 1.7e-05 24.6 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4116 PF13475.6 PVD37112.1 - 0.057 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) CCDC50_N PF15295.6 PVD37113.1 - 1.8e-28 99.2 19.3 1.8e-28 99.2 19.3 3.3 3 1 1 4 4 4 2 Coiled-coil domain-containing protein 50 N-terminus TPKR_C2 PF16920.5 PVD37113.1 - 0.064 13.4 0.1 0.28 11.3 0.1 2.2 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain TctC PF03401.14 PVD37113.1 - 0.18 10.9 1.7 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor Cwf_Cwc_15 PF04889.12 PVD37113.1 - 7.4 6.2 35.2 3 7.5 20.1 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ank_2 PF12796.7 PVD37114.1 - 6.7e-57 190.0 9.7 9e-16 58.2 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37114.1 - 2.3e-38 130.1 5.9 2.6e-08 34.2 0.0 7.7 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD37114.1 - 3.2e-38 128.5 3.6 1.1e-05 25.6 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PVD37114.1 - 1.9e-35 120.5 2.4 4.7e-10 39.5 0.0 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) SH3_15 PF18346.1 PVD37114.1 - 9e-28 96.4 0.2 1.2e-17 64.0 0.1 2.7 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain Ank_3 PF13606.6 PVD37114.1 - 6.7e-26 87.5 3.0 0.0002 21.6 0.0 9.3 8 1 1 9 9 9 4 Ankyrin repeat MIB_HERC2 PF06701.13 PVD37114.1 - 2.3e-25 88.6 9.3 1.6e-12 47.5 2.5 3.2 3 0 0 3 3 3 2 Mib_herc2 ZZ PF00569.17 PVD37114.1 - 6.9e-12 45.0 6.2 6.9e-12 45.0 6.2 2.9 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C3HC4_3 PF13920.6 PVD37114.1 - 1.5e-07 31.2 14.0 1.5e-07 31.2 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD37114.1 - 0.0056 16.5 13.5 0.0056 16.5 13.5 2.4 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 UnbV_ASPIC PF07593.12 PVD37114.1 - 0.66 10.0 5.8 6.6 6.8 0.1 4.6 6 0 0 6 6 6 0 ASPIC and UnbV DUF2039 PF10217.9 PVD37114.1 - 0.8 10.1 16.4 0.044 14.1 7.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 PVD37114.1 - 6.5 6.8 22.1 0.23 11.4 13.2 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Ion_trans PF00520.31 PVD37116.1 - 0.0035 16.6 21.4 0.0096 15.2 21.4 1.8 1 1 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 PVD37116.1 - 0.0037 16.5 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 PVD37117.1 - 0.0012 18.1 4.7 0.0037 16.5 4.7 1.8 1 1 0 1 1 1 1 Ion transport protein Bacillus_HBL PF05791.11 PVD37117.1 - 0.0071 16.2 2.7 0.0076 16.1 0.4 2.2 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) MRP-S28 PF10213.9 PVD37117.1 - 0.11 12.9 7.0 0.043 14.3 3.4 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein DUF3671 PF12420.8 PVD37117.1 - 0.14 12.2 4.2 2.8 8.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function Orf78 PF06024.12 PVD37117.1 - 0.33 11.3 2.5 0.79 10.1 0.0 2.8 3 0 0 3 3 3 0 Orf78 (ac78) RIFIN PF02009.16 PVD37117.1 - 0.35 10.7 9.1 0.43 10.4 0.0 3.0 2 1 1 3 3 3 0 Rifin PKD_channel PF08016.12 PVD37117.1 - 0.51 9.0 8.5 1.4 7.5 8.5 1.7 1 1 0 1 1 1 0 Polycystin cation channel Plk4_PB2 PF18409.1 PVD37117.1 - 0.76 10.5 11.0 0.29 11.8 1.0 3.4 3 1 0 4 4 3 0 Polo-like Kinase 4 Polo Box 2 Sigma_reg_N PF13800.6 PVD37117.1 - 1.1 9.6 6.3 7.5 6.9 0.9 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal T3SSipB PF16535.5 PVD37117.1 - 1.3 9.5 7.5 0.26 11.7 0.9 2.7 1 1 2 3 3 3 0 Type III cell invasion protein SipB MCPsignal PF00015.21 PVD37117.1 - 1.7 8.4 4.3 10 5.9 0.5 2.7 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Surfac_D-trimer PF09006.11 PVD37117.1 - 1.8 8.5 3.7 4.7 7.2 0.2 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Syntaxin_2 PF14523.6 PVD37117.1 - 2.8 8.4 17.8 0.38 11.1 6.5 3.6 3 2 0 3 3 3 0 Syntaxin-like protein Goodbye PF17109.5 PVD37117.1 - 4.5 7.8 8.5 11 6.5 0.2 3.8 3 1 0 4 4 4 0 fungal STAND N-terminal Goodbye domain Laminin_II PF06009.12 PVD37117.1 - 7 6.7 9.8 16 5.5 2.3 3.2 1 1 2 3 3 3 0 Laminin Domain II Spore_III_AB PF09548.10 PVD37117.1 - 8.8 6.4 7.4 21 5.2 0.2 2.9 3 0 0 3 3 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1664 PF07889.12 PVD37117.1 - 8.9 6.4 6.5 12 6.0 0.7 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) LSDAT_euk PF18139.1 PVD37118.1 - 9.7e-07 28.4 0.0 0.0003 20.3 0.0 3.1 3 0 0 3 3 3 1 SLOG in TRPM LSDAT_prok PF18171.1 PVD37118.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 PVD37118.1 - 0.012 14.8 26.3 0.028 13.6 26.3 1.7 1 1 0 1 1 1 0 Ion transport protein SK_channel PF03530.14 PVD37118.1 - 0.013 15.5 5.3 0.059 13.4 5.3 2.2 1 1 0 1 1 1 0 Calcium-activated SK potassium channel HV_small_capsid PF17086.5 PVD37118.1 - 0.11 12.9 0.1 0.8 10.0 0.0 2.4 2 0 0 2 2 2 0 Small capsid protein of Herpesviridae NEMO PF11577.8 PVD37118.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.9 4 0 0 4 4 4 0 NF-kappa-B essential modulator NEMO ABC_membrane PF00664.23 PVD37119.1 - 3.3e-68 230.3 35.7 2.2e-35 122.7 16.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PVD37119.1 - 4.5e-54 182.7 0.1 2.2e-26 93.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD37119.1 - 2.9e-11 43.2 0.0 4.9e-05 22.9 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PVD37119.1 - 1.4e-07 31.5 0.7 2.5e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PVD37119.1 - 2.2e-07 31.4 0.6 0.00098 19.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PVD37119.1 - 4.1e-07 30.1 2.2 0.0023 18.0 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 PVD37119.1 - 1.7e-06 28.2 0.3 0.00019 21.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 PVD37119.1 - 2.1e-05 23.9 0.8 0.0051 16.1 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 PVD37119.1 - 0.00027 20.6 0.5 0.086 12.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 PVD37119.1 - 0.00034 20.8 6.0 0.19 11.8 0.5 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain DUF815 PF05673.13 PVD37119.1 - 0.0017 17.5 0.1 0.86 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 PVD37119.1 - 0.0053 16.4 0.1 0.42 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD37119.1 - 0.0097 15.6 4.4 0.19 11.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PVD37119.1 - 0.021 15.1 1.5 3.8 7.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 PVD37119.1 - 0.025 13.4 0.2 2.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Roc PF08477.13 PVD37119.1 - 0.03 14.6 0.3 3 8.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 PVD37119.1 - 0.032 14.7 3.9 0.31 11.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain IIGP PF05049.13 PVD37119.1 - 0.046 12.8 2.0 0.21 10.6 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 PVD37119.1 - 0.068 12.7 0.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region HSL_N PF06350.12 PVD37119.1 - 0.07 12.1 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus AIG1 PF04548.16 PVD37119.1 - 0.089 12.1 3.9 0.28 10.5 0.3 2.5 2 0 0 2 2 2 0 AIG1 family T2SSE PF00437.20 PVD37119.1 - 0.093 11.8 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 PVD37119.1 - 0.11 11.7 1.1 0.72 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 PVD37119.1 - 0.12 11.6 1.9 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 PVD37119.1 - 0.17 11.6 0.3 10 5.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 PVD37119.1 - 0.22 10.5 1.7 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 PVD37119.1 - 0.4 10.4 1.4 24 4.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 PVD37119.1 - 0.77 9.6 2.8 0.96 9.3 0.1 2.5 3 0 0 3 3 2 0 NACHT domain DUF2852 PF11014.8 PVD37119.1 - 2.1 8.5 5.4 3.7 7.7 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Ank_2 PF12796.7 PVD37120.1 - 4.9e-27 94.3 0.4 1e-05 26.0 0.0 6.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37120.1 - 4.9e-19 68.4 1.6 0.00058 20.4 0.0 8.2 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37120.1 - 2e-15 55.3 10.5 0.044 14.3 0.0 9.9 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 PVD37120.1 - 7e-15 54.9 5.1 0.0075 16.6 0.3 8.0 5 2 3 8 8 8 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD37120.1 - 1.9e-07 31.3 0.2 6e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 SOCS box Ank PF00023.30 PVD37120.1 - 0.00018 21.8 11.0 1.6 9.3 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat PRKCSH PF07915.13 PVD37121.1 - 8e-16 58.8 3.3 8e-16 58.8 3.3 3.6 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PVD37121.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Exotox-A_cataly PF09009.10 PVD37121.1 - 0.082 12.7 1.2 0.23 11.2 1.2 1.7 1 0 0 1 1 1 0 Exotoxin A catalytic ELM2 PF01448.24 PVD37121.1 - 0.11 13.2 0.4 1.3 9.9 0.1 3.0 2 0 0 2 2 2 0 ELM2 domain R3H PF01424.22 PVD37122.1 - 3.1e-09 36.7 0.0 7.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 PVD37122.1 - 1.9e-05 25.3 3.4 1.9e-05 25.3 3.4 2.6 2 0 0 2 2 2 1 SUZ domain Ig_3 PF13927.6 PVD37123.1 - 5.6e-125 408.2 11.6 5.5e-13 49.3 0.2 14.9 14 0 0 14 14 14 12 Immunoglobulin domain I-set PF07679.16 PVD37123.1 - 2.3e-105 344.9 0.0 3.3e-12 46.3 0.0 13.5 14 0 0 14 14 13 12 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD37123.1 - 3.3e-88 290.1 18.3 1.5e-08 34.8 0.0 14.5 13 1 1 14 14 14 12 Immunoglobulin domain ig PF00047.25 PVD37123.1 - 2.9e-68 226.1 14.1 4.7e-09 36.3 0.0 14.0 14 0 0 14 14 14 10 Immunoglobulin domain fn3 PF00041.21 PVD37123.1 - 2.3e-45 152.9 44.5 1e-10 41.8 0.6 9.6 9 1 0 9 9 9 8 Fibronectin type III domain V-set PF07686.17 PVD37123.1 - 2.2e-20 72.8 39.6 0.0004 20.5 0.2 17.2 16 7 3 19 19 16 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD37123.1 - 1.6e-15 56.4 0.8 0.047 13.3 0.0 9.9 12 0 0 12 12 10 2 Immunoglobulin domain Ig_5 PF16681.5 PVD37123.1 - 1.3e-11 44.7 0.0 0.74 10.3 0.0 8.8 9 0 0 9 9 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD37123.1 - 5.9e-08 32.7 3.0 0.065 13.3 0.0 8.3 10 0 0 10 10 7 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD37123.1 - 3.8e-07 30.2 0.2 0.31 11.3 0.0 6.1 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Ig_C17orf99 PF17736.1 PVD37123.1 - 1.5e-05 25.0 7.5 0.24 11.4 0.0 7.5 7 1 0 7 7 7 1 C17orf99 Ig domain V-set_CD47 PF08204.11 PVD37123.1 - 2.3e-05 24.4 2.7 8 6.5 0.0 6.3 7 0 0 7 7 6 1 CD47 immunoglobulin-like domain Lectin_C PF00059.21 PVD37123.1 - 0.00036 21.2 0.1 0.0013 19.5 0.1 2.0 1 0 0 1 1 1 1 Lectin C-type domain DivIC PF04977.15 PVD37123.1 - 0.042 13.6 2.2 2.2 8.1 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 PVD37123.1 - 0.042 14.3 4.3 2.3 8.7 0.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Pur_ac_phosph_N PF16656.5 PVD37123.1 - 0.12 13.0 19.4 0.15 12.7 0.2 6.6 6 0 0 6 6 5 0 Purple acid Phosphatase, N-terminal domain AcylCoA_dehyd_C PF12186.8 PVD37123.1 - 0.15 12.2 0.7 5.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF4201 PF13870.6 PVD37123.1 - 0.26 11.0 0.1 9.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Vir_act_alpha_C PF10400.9 PVD37123.1 - 0.3 11.8 1.0 43 4.9 0.1 2.6 2 0 0 2 2 2 0 Virulence activator alpha C-term GARP PF16731.5 PVD37123.1 - 0.82 9.3 5.0 5.5 6.6 0.5 2.2 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Wbp11 PF09429.10 PVD37123.1 - 2.9 8.3 3.7 30 5.1 0.4 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 FlaC_arch PF05377.11 PVD37123.1 - 5.7 7.4 4.9 15 6.1 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPK_catalytic PF04263.16 PVD37124.1 - 7e-30 103.5 0.1 1.1e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 PVD37124.1 - 2.7e-22 78.3 0.4 5.5e-22 77.3 0.1 1.7 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TcpF PF06340.11 PVD37124.1 - 0.061 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F Sugar_tr PF00083.24 PVD37125.1 - 6.3e-31 107.7 16.5 6.3e-31 107.7 16.5 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD37125.1 - 1e-23 83.9 25.3 1.8e-23 83.0 25.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 PVD37125.1 - 3.5e-05 23.3 9.0 0.0001 21.8 9.0 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1500 PF07389.12 PVD37125.1 - 0.059 13.4 0.2 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) Arrestin_C PF02752.22 PVD37126.1 - 1.5e-07 31.9 0.0 1.4e-06 28.8 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD37126.1 - 2.3e-06 27.7 0.1 0.00022 21.3 0.1 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 PVD37126.1 - 0.0023 17.2 0.3 0.0096 15.1 0.2 1.8 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 PVD37127.1 - 6.4e-10 39.3 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD37127.1 - 2.4e-09 37.7 0.0 6e-07 30.0 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD37127.1 - 0.0055 15.9 0.3 0.1 11.7 0.2 2.1 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 PVD37128.1 - 3.3e-11 43.8 0.0 6e-09 36.5 0.0 2.9 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD37128.1 - 0.0085 16.1 0.0 0.054 13.6 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 PVD37128.1 - 0.049 12.8 0.2 0.28 10.3 0.1 2.0 1 1 1 2 2 2 0 Rgp1 Arrestin_N PF00339.29 PVD37129.1 - 1.3e-13 51.3 0.0 2.3e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD37129.1 - 2e-12 47.7 0.0 0.0028 18.1 0.0 4.0 4 0 0 4 4 4 3 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PVD37129.1 - 0.00015 21.1 0.4 0.32 10.1 0.1 2.4 2 0 0 2 2 2 2 Rgp1 UBM PF14377.6 PVD37129.1 - 0.29 10.6 0.8 0.88 9.1 0.8 1.8 1 0 0 1 1 1 0 Ubiquitin binding region Arrestin_C PF02752.22 PVD37130.1 - 1.8e-13 51.1 0.0 1.3e-06 28.9 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD37130.1 - 0.00021 21.4 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Thyroglobulin_1 PF00086.18 PVD37133.1 - 4.7e-22 77.4 18.4 1.7e-08 34.0 0.6 3.6 1 1 2 3 3 3 3 Thyroglobulin type-1 repeat DUF3823 PF12866.7 PVD37133.1 - 0.07 13.4 0.0 15 6.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3823) N-terminal domain Sugar_tr PF00083.24 PVD37134.1 - 6.8e-27 94.4 16.1 9.7e-27 93.9 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD37134.1 - 3.6e-19 68.9 33.6 6e-09 35.3 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NDUF_B12 PF08122.12 PVD37134.1 - 3.7 7.7 5.4 4 7.6 0.1 3.5 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family Arrestin_C PF02752.22 PVD37135.1 - 6.1e-12 46.2 0.0 7e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD37135.1 - 6.9e-07 29.4 0.0 4.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ANT PF03374.14 PVD37136.1 - 0.26 11.6 2.4 21 5.5 0.3 3.3 1 1 2 3 3 3 0 Phage antirepressor protein KilAC domain Thyroglobulin_1 PF00086.18 PVD37137.1 - 3.3e-14 52.3 12.9 1.7e-07 30.8 0.3 3.0 1 1 2 3 3 3 2 Thyroglobulin type-1 repeat DUF5321 PF17254.2 PVD37138.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Sugar_tr PF00083.24 PVD37139.1 - 1.7e-09 37.0 1.2 2.5e-09 36.5 1.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD37139.1 - 5.6e-07 28.8 3.9 8.9e-07 28.1 3.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMP_2 PF06791.13 PVD37139.1 - 0.0032 17.2 1.0 0.0049 16.6 1.0 1.2 1 0 0 1 1 1 1 Prophage tail length tape measure protein bZIP_Maf PF03131.17 PVD37140.1 - 3.8e-16 59.4 2.6 3.8e-16 59.4 2.6 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 PVD37140.1 - 2.7e-06 27.4 5.3 8.2e-06 25.8 5.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD37140.1 - 0.0049 16.9 4.9 0.0049 16.9 4.9 2.4 3 0 0 3 3 3 1 Basic region leucine zipper DUF2934 PF11154.8 PVD37141.1 - 0.13 12.0 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) TetR_C_18 PF17923.1 PVD37142.1 - 0.089 13.3 0.2 24 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Inhibitor_I68 PF10468.9 PVD37143.1 - 0.046 14.1 2.6 0.12 12.8 2.6 1.7 1 1 0 1 1 1 0 Carboxypeptidase inhibitor I68 COE1_DBD PF16422.5 PVD37143.1 - 0.1 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain Homeodomain PF00046.29 PVD37146.1 - 1.3e-22 79.4 7.8 1.9e-22 78.8 7.8 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 PVD37146.1 - 0.00044 19.9 0.5 0.00066 19.4 0.5 1.3 1 0 0 1 1 1 1 QLQ BUD22 PF09073.10 PVD37146.1 - 0.021 14.2 8.9 0.023 14.1 8.9 1.1 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 PVD37146.1 - 0.32 11.2 14.1 0.46 10.7 14.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 PVD37146.1 - 1.3 7.7 4.0 1.5 7.5 4.0 1.0 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 PVD37146.1 - 1.9 7.8 10.9 2.6 7.3 10.9 1.3 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 PVD37146.1 - 9 5.0 9.2 11 4.6 9.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribul_P_3_epim PF00834.19 PVD37147.1 - 1.5e-68 230.1 0.0 1.8e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 PVD37147.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain 7tm_1 PF00001.21 PVD37148.1 - 3e-08 33.3 7.5 3.9e-08 32.9 7.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2011 PF09428.10 PVD37148.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) KH_4 PF13083.6 PVD37149.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 KH domain Ig_3 PF13927.6 PVD37150.1 - 1.7e-64 214.4 6.8 1.2e-11 45.1 0.1 7.4 8 0 0 8 8 8 6 Immunoglobulin domain I-set PF07679.16 PVD37150.1 - 4.3e-55 183.7 0.0 3.9e-13 49.3 0.0 7.6 7 1 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD37150.1 - 3.7e-53 177.8 6.7 3.9e-09 36.7 0.0 6.7 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 PVD37150.1 - 3.3e-36 123.3 1.5 1.4e-07 31.6 0.0 6.9 6 1 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 PVD37150.1 - 1.4e-20 73.4 4.1 8.6e-09 35.6 0.0 4.9 5 0 0 5 5 4 3 Fibronectin type III domain V-set PF07686.17 PVD37150.1 - 2.2e-18 66.4 17.7 0.0023 18.1 0.0 10.4 7 5 2 9 9 9 4 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD37150.1 - 1.4e-15 56.5 0.0 0.013 15.1 0.0 6.1 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 PVD37150.1 - 4.7e-11 42.9 0.1 0.09 13.2 0.0 6.6 7 0 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 PVD37150.1 - 1.8e-07 31.1 2.7 0.95 9.6 0.3 5.3 4 1 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 PVD37150.1 - 3.8e-07 30.1 0.2 3.6 7.7 0.0 5.7 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 PVD37150.1 - 1.8e-06 27.9 0.1 0.25 11.4 0.0 4.7 5 0 0 5 5 5 2 C17orf99 Ig domain Receptor_2B4 PF11465.8 PVD37150.1 - 4e-06 27.0 0.0 13 6.0 0.0 5.4 5 0 0 5 5 5 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 PVD37150.1 - 0.0012 18.9 0.5 0.69 9.9 0.0 4.3 3 1 1 4 4 4 1 CD47 immunoglobulin-like domain Pur_ac_phosph_N PF16656.5 PVD37150.1 - 0.0067 17.0 1.3 0.12 12.9 0.0 3.3 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Adeno_E3_CR1 PF02440.15 PVD37150.1 - 0.011 15.4 0.3 1.4 8.7 0.0 3.8 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 YtkA PF13115.6 PVD37150.1 - 0.024 15.2 0.0 1.4 9.5 0.0 2.9 2 0 0 2 2 2 0 YtkA-like C2-set PF05790.15 PVD37150.1 - 0.031 14.5 0.0 27 5.0 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Ig_3 PF13927.6 PVD37151.1 - 8.1e-61 202.6 1.2 2.3e-11 44.1 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 PVD37151.1 - 2.8e-47 158.7 0.0 1.3e-10 41.2 0.0 7.0 6 1 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD37151.1 - 2.1e-44 149.7 6.1 3.4e-10 40.1 0.0 7.1 6 1 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 PVD37151.1 - 6.4e-37 125.6 1.6 1.6e-07 31.4 0.0 7.2 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 PVD37151.1 - 1e-21 77.1 12.1 0.001 19.2 0.0 9.8 7 4 0 7 7 7 5 Immunoglobulin V-set domain fn3 PF00041.21 PVD37151.1 - 5.7e-19 68.3 5.9 1.5e-08 34.8 0.1 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Ig_6 PF18452.1 PVD37151.1 - 3.1e-11 42.7 0.0 0.28 10.8 0.0 6.1 6 0 0 6 6 6 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD37151.1 - 2.8e-10 40.1 0.3 0.056 13.5 0.0 5.4 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain Lectin_C PF00059.21 PVD37151.1 - 1.1e-06 29.3 0.1 3.7e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 PVD37151.1 - 0.0004 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like C2-set_2 PF08205.12 PVD37151.1 - 0.005 16.9 0.3 1.3 9.2 0.0 3.8 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD37151.1 - 0.028 15.0 0.5 0.18 12.4 0.0 2.6 3 0 0 3 3 2 0 Purple acid Phosphatase, N-terminal domain C2-set PF05790.15 PVD37151.1 - 0.096 12.9 0.0 46 4.3 0.0 4.0 5 0 0 5 5 4 0 Immunoglobulin C2-set domain YtkA PF13115.6 PVD37151.1 - 0.12 13.0 0.0 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 YtkA-like DUF740 PF05340.12 PVD37151.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Adeno_E3_CR1 PF02440.15 PVD37151.1 - 0.15 11.8 0.1 7 6.5 0.0 3.5 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Ig_3 PF13927.6 PVD37152.1 - 5.5e-10 39.7 0.0 0.0002 21.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD37152.1 - 3.9e-07 30.0 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD37152.1 - 7.9e-07 29.2 0.6 0.0055 16.9 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD37152.1 - 1.4e-05 25.4 0.1 0.049 14.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 PVD37152.1 - 3.7e-05 23.2 0.0 0.019 14.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD37152.1 - 0.0033 17.6 0.1 0.94 9.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain zf-RRN7 PF11781.8 PVD37152.1 - 0.14 11.9 0.7 6.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ig_3 PF13927.6 PVD37153.1 - 2.7e-27 95.2 0.0 2.2e-15 57.0 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 PVD37153.1 - 2.6e-24 85.3 0.9 1.3e-12 47.9 0.0 3.8 3 1 1 4 4 4 3 Immunoglobulin domain I-set PF07679.16 PVD37153.1 - 4.1e-24 84.5 0.0 8.3e-15 54.6 0.0 3.6 2 1 1 3 3 3 3 Immunoglobulin I-set domain fn3 PF00041.21 PVD37153.1 - 2.7e-20 72.5 2.5 1.9e-05 24.9 0.0 4.7 4 1 0 4 4 4 3 Fibronectin type III domain ig PF00047.25 PVD37153.1 - 1e-15 57.6 1.5 8.7e-06 25.8 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 PVD37153.1 - 5.3e-09 36.2 0.2 0.055 13.7 0.0 3.8 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD37153.1 - 9.3e-07 28.3 0.0 0.16 11.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD37153.1 - 0.0018 18.3 0.0 6.7 6.8 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD37153.1 - 0.061 13.4 0.2 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 PVD37153.1 - 0.11 12.5 0.0 19 5.2 0.0 3.3 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain PP2C_2 PF13672.6 PVD37155.1 - 2.2e-08 34.0 0.0 5.6e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 PVD37155.1 - 0.017 15.0 0.2 0.22 11.4 0.0 2.6 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) GATase_5 PF13507.6 PVD37155.1 - 0.066 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain BRCT PF00533.26 PVD37157.1 - 7.5e-42 141.6 2.6 4.7e-08 33.3 0.0 9.0 8 1 1 9 9 9 7 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PVD37157.1 - 4.1e-38 129.1 11.6 2.1e-11 43.6 0.1 6.8 5 1 1 6 6 6 6 twin BRCT domain BRCT_2 PF16589.5 PVD37157.1 - 7.4e-17 61.5 0.5 0.027 14.9 0.0 6.9 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PVD37157.1 - 2.7e-11 43.2 0.0 2.4e-05 24.1 0.0 5.2 6 0 0 6 6 6 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 PVD37157.1 - 0.0098 15.9 2.0 62 3.8 0.0 5.9 7 0 0 7 7 7 0 BRCA1 C Terminus (BRCT) domain Acyl_transf_3 PF01757.22 PVD37159.1 - 5e-19 68.5 35.9 6.5e-19 68.2 35.9 1.1 1 0 0 1 1 1 1 Acyltransferase family Bac_export_2 PF01312.19 PVD37159.1 - 3.1 6.9 5.3 3.6 6.7 0.7 2.4 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family G-alpha PF00503.20 PVD37160.1 - 1.3e-80 271.3 0.1 1.5e-80 271.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD37160.1 - 1.1e-12 47.8 1.8 1.6e-09 37.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD37160.1 - 2.8e-05 23.6 0.5 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 PVD37160.1 - 0.0031 17.7 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 PVD37160.1 - 0.076 12.7 0.6 6.8 6.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain GTP_EFTU PF00009.27 PVD37160.1 - 0.085 12.4 0.2 5.1 6.6 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain F-box-like PF12937.7 PVD37161.1 - 9.3e-11 41.5 0.5 1.8e-10 40.6 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD37161.1 - 3.9e-07 29.8 0.2 7.8e-07 28.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37161.1 - 0.00022 20.7 0.1 0.00046 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PVD37162.1 - 1.6e-09 37.5 1.3 4e-09 36.2 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD37162.1 - 1.3e-05 24.9 0.2 4.3e-05 23.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37162.1 - 0.0027 17.2 0.1 0.0067 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PVD37164.1 - 3.2e-09 36.5 2.1 6.3e-09 35.6 2.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD37164.1 - 5.2e-07 29.4 0.3 1.1e-06 28.3 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37164.1 - 0.0071 15.9 0.6 0.017 14.7 0.6 1.6 1 0 0 1 1 1 1 F-box UreF PF01730.16 PVD37164.1 - 0.011 16.3 0.6 0.023 15.3 0.6 1.7 1 1 0 1 1 1 0 UreF DUF5478 PF17572.2 PVD37164.1 - 0.092 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5478) F-box-like PF12937.7 PVD37166.1 - 1.5e-09 37.6 2.8 1.5e-09 37.6 2.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD37166.1 - 1.6e-06 27.8 0.4 4e-06 26.6 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37166.1 - 0.0019 17.7 1.5 0.0024 17.4 0.2 1.9 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 PVD37167.1 - 4.9e-09 35.9 0.4 1e-08 34.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PVD37167.1 - 2.7e-06 27.1 0.1 8.5e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37167.1 - 0.002 17.6 0.1 0.0077 15.8 0.1 2.0 1 0 0 1 1 1 1 F-box CSD PF00313.22 PVD37168.1 - 3.6e-06 26.7 0.1 6.4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF4918 PF16265.5 PVD37169.1 - 1.6e-06 27.8 0.0 5.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4918) FA_hydroxylase PF04116.13 PVD37170.1 - 2.9e-25 89.1 20.4 2.9e-25 89.1 20.4 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 PVD37172.1 - 1.5e-16 59.8 36.6 0.00051 20.4 0.4 6.4 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD37172.1 - 4.6e-12 45.8 25.4 7.1e-06 26.2 0.9 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD37172.1 - 3.6e-06 27.4 25.1 0.027 15.3 0.3 6.6 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 PVD37172.1 - 0.00014 22.4 26.3 0.017 15.7 2.9 6.4 2 1 4 6 6 5 2 FOXP coiled-coil domain zf_ZIC PF18366.1 PVD37172.1 - 0.48 10.6 9.7 0.45 10.7 0.4 4.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 PVD37172.1 - 0.75 9.9 13.9 0.19 11.9 1.8 3.7 2 1 2 4 4 4 0 Aberrant zinc-finger PcF PF09461.10 PVD37172.1 - 0.76 10.2 6.2 48 4.4 0.2 4.0 2 1 1 3 3 3 0 Phytotoxin PcF protein zf-C2H2_8 PF15909.5 PVD37172.1 - 0.78 10.1 13.4 0.41 11.0 1.7 4.2 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PVD37172.1 - 4.8 7.6 13.1 10 6.6 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD37172.1 - 6.5 6.9 11.0 2.1 8.4 1.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD37172.1 - 8.8 6.2 9.6 2.3 8.1 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HLH PF00010.26 PVD37176.1 - 9.3e-14 51.1 0.0 2.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5343 PF17278.2 PVD37176.1 - 0.15 12.1 2.6 2.7 8.1 0.1 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5343) Snf7 PF03357.21 PVD37177.1 - 6.5e-35 120.3 22.9 7e-20 71.3 8.6 2.0 1 1 1 2 2 2 2 Snf7 ATF7IP_BD PF16788.5 PVD37177.1 - 0.006 16.7 4.6 0.0077 16.4 4.6 1.1 1 0 0 1 1 1 1 ATF-interacting protein binding domain FAP206 PF12018.8 PVD37177.1 - 0.024 14.2 4.4 0.034 13.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function Serine_rich PF08824.10 PVD37177.1 - 0.052 13.6 3.8 0.078 13.0 3.8 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF1319 PF07028.11 PVD37177.1 - 0.12 12.6 4.5 0.14 12.3 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Exonuc_VII_L PF02601.15 PVD37177.1 - 0.12 11.9 3.1 0.15 11.6 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GvpK PF05121.12 PVD37177.1 - 0.21 11.7 9.7 0.85 9.7 0.7 3.0 2 1 1 3 3 3 0 Gas vesicle protein K DUF4407 PF14362.6 PVD37177.1 - 0.22 10.8 2.5 0.32 10.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 PVD37177.1 - 0.62 10.1 16.7 3.8 7.6 17.1 1.9 1 1 1 2 2 2 0 FlxA-like protein NPV_P10 PF05531.12 PVD37177.1 - 0.68 10.4 5.1 18 5.9 0.8 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 PVD37177.1 - 0.69 7.8 5.9 0.89 7.4 5.9 1.1 1 0 0 1 1 1 0 Prominin FliJ PF02050.16 PVD37177.1 - 1 9.6 14.6 0.16 12.2 8.5 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein DUF2802 PF10975.8 PVD37177.1 - 4.7 7.4 7.6 33 4.7 7.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) FapA PF03961.13 PVD37177.1 - 5.1 5.6 11.4 6.3 5.3 10.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 PVD37177.1 - 5.7 7.3 17.5 0.3 11.5 10.0 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC-167 PF15188.6 PVD37177.1 - 5.9 7.3 9.8 0.4 11.0 0.7 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4918 PF16265.5 PVD37179.1 - 7e-08 32.3 0.0 9.4e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4918) Condensin2nSMC PF12422.8 PVD37180.1 - 1.1e-54 184.6 0.3 7.2e-53 178.8 0.0 3.6 4 0 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 PVD37180.1 - 6.7e-05 22.8 8.7 0.77 10.2 0.1 6.1 5 1 1 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 PVD37180.1 - 0.0039 17.5 1.0 0.26 11.7 0.1 3.7 2 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 PVD37180.1 - 0.019 15.0 4.4 1.6 8.7 0.1 3.9 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF1902 PF08972.11 PVD37180.1 - 0.074 13.0 0.1 0.4 10.7 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) GGACT PF06094.12 PVD37181.1 - 5.7e-19 68.9 0.2 7.3e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PVD37181.1 - 0.13 12.7 0.1 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 AIG2-like family GGACT PF06094.12 PVD37182.1 - 6.8e-18 65.4 0.1 9.3e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PVD37182.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 AIG2-like family CDV3 PF15359.6 PVD37183.1 - 1.4e-30 106.4 9.8 1.4e-30 106.4 9.8 1.9 2 1 0 2 2 2 1 Carnitine deficiency-associated protein 3 Diphthamide_syn PF01866.17 PVD37184.1 - 6e-98 328.0 0.1 7.7e-98 327.7 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein YabA PF06156.13 PVD37185.1 - 0.0081 16.8 4.7 0.0081 16.8 4.7 2.5 1 1 1 2 2 2 1 Initiation control protein YabA bZIP_1 PF00170.21 PVD37185.1 - 0.1 12.7 13.9 0.3 11.2 13.9 1.8 1 1 0 1 1 1 0 bZIP transcription factor IFT20 PF14931.6 PVD37185.1 - 0.15 12.2 6.2 0.36 11.0 6.2 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF1151 PF06625.11 PVD37185.1 - 0.29 11.1 10.8 0.61 10.1 10.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) MalF_P2 PF14785.6 PVD37185.1 - 0.54 10.3 4.2 0.16 12.0 1.0 1.8 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain HIP1_clath_bdg PF16515.5 PVD37185.1 - 1.9 9.1 12.0 0.77 10.4 7.5 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UCH_C PF18031.1 PVD37185.1 - 3.6 7.6 8.0 0.16 11.9 1.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Cnn_1N PF07989.11 PVD37185.1 - 3.9 7.7 11.6 7.5 6.8 0.7 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 UQ_con PF00179.26 PVD37186.1 - 3.3e-29 101.3 0.0 6e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PVD37186.1 - 0.00034 20.5 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 PVD37186.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF4542 PF15075.6 PVD37187.1 - 6.2e-23 81.7 1.5 9e-11 42.3 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4542) PCO_ADO PF07847.12 PVD37187.1 - 0.017 14.6 0.5 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 PCO_ADO DUF4542 PF15075.6 PVD37188.1 - 1.1e-51 174.7 0.1 1.4e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) Pyridoxal_deC PF00282.19 PVD37189.1 - 4.1e-81 272.6 0.3 1.5e-78 264.2 0.2 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PVD37189.1 - 2.4e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 PVD37189.1 - 0.00014 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Zip PF02535.22 PVD37190.1 - 5.5e-54 183.6 13.9 5.5e-54 183.6 13.9 2.4 1 1 0 2 2 2 1 ZIP Zinc transporter YwiC PF14256.6 PVD37190.1 - 0.3 11.4 4.8 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 YwiC-like protein Alpha-amylase PF00128.24 PVD37191.1 - 2.8e-63 214.5 0.4 4.9e-63 213.7 0.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 PVD37191.1 - 4.2e-17 61.5 0.4 7.3e-17 60.7 0.4 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Glyco_hydro_77 PF02446.17 PVD37191.1 - 0.061 12.2 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase GH97_C PF14509.6 PVD37191.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF3459 PF11941.8 PVD37191.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) NHL PF01436.21 PVD37192.1 - 1.5e-25 87.9 7.1 2.5e-09 36.7 0.0 6.1 6 1 0 6 6 6 4 NHL repeat SGL PF08450.12 PVD37192.1 - 8.1e-09 35.4 0.3 0.011 15.3 0.0 3.5 2 2 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PVD37192.1 - 0.0062 15.7 0.6 0.057 12.6 0.0 2.7 1 1 2 3 3 3 1 6-bladed beta-propeller DUF2173 PF09941.9 PVD37192.1 - 0.091 13.1 0.0 0.42 10.9 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2173) Phytase-like PF13449.6 PVD37192.1 - 0.15 12.0 0.0 19 5.1 0.0 2.7 3 0 0 3 3 3 0 Esterase-like activity of phytase DUF4430 PF14478.6 PVD37193.1 - 2.2e-11 44.2 15.8 0.014 16.0 0.2 4.4 4 1 0 4 4 4 4 Domain of unknown function (DUF4430) STE PF02200.16 PVD37193.1 - 0.0013 19.2 4.0 38 4.7 0.1 4.2 4 0 0 4 4 4 0 STE like transcription factor zf-C3HC4_3 PF13920.6 PVD37193.1 - 0.023 14.5 5.0 6.2 6.8 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) COBRA PF04833.15 PVD37193.1 - 0.03 14.2 1.6 0.4 10.6 0.1 2.7 3 0 0 3 3 3 0 COBRA-like protein DnaJ_CXXCXGXG PF00684.19 PVD37193.1 - 0.12 12.8 6.0 0.3 11.5 0.2 3.2 3 0 0 3 3 3 0 DnaJ central domain DUF5596 PF18082.1 PVD37193.1 - 0.77 9.6 3.2 10 6.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) ASFV_360 PF01671.16 PVD37193.1 - 0.87 9.0 6.9 6.6 6.2 0.1 3.4 4 0 0 4 4 4 0 African swine fever virus multigene family 360 protein DZR PF12773.7 PVD37193.1 - 8.5 6.5 9.3 11 6.1 0.5 3.1 3 0 0 3 3 3 0 Double zinc ribbon RVT_1 PF00078.27 PVD37194.1 - 2.5e-16 59.9 0.0 2.9e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hus1 PF04005.12 PVD37195.1 - 5.9e-76 255.4 0.0 6.5e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein TraH PF06122.11 PVD37195.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein PNP_UDP_1 PF01048.20 PVD37196.1 - 5.3e-23 81.5 0.0 7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DAGK_acc PF00609.19 PVD37197.1 - 2.2e-52 177.6 0.0 4.5e-52 176.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 PVD37197.1 - 5.3e-48 163.4 1.3 4.7e-47 160.3 0.3 2.7 2 1 0 2 2 2 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 PVD37197.1 - 1.5e-26 92.5 0.0 2.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PVD37197.1 - 2.2e-23 81.9 28.2 6.9e-13 48.3 6.7 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 PVD37197.1 - 4.5e-10 38.3 2.0 0.00016 21.0 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PVD37197.1 - 2.7e-08 34.1 1.1 6.4e-08 32.9 0.5 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD37197.1 - 2.1e-07 30.1 1.4 0.003 17.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PVD37197.1 - 3.1e-07 29.8 0.2 0.00071 19.3 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PVD37197.1 - 1.7e-06 27.7 0.2 0.03 14.2 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain pair C1_2 PF03107.16 PVD37197.1 - 0.081 13.3 17.6 1.1 9.7 4.2 2.6 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 PVD37197.1 - 1.5 8.8 20.8 3 7.8 5.4 2.9 2 0 0 2 2 2 0 PHD-finger UCH PF00443.29 PVD37200.1 - 7.2e-35 120.7 4.8 2.5e-33 115.7 4.8 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD37200.1 - 8.7e-09 35.4 1.0 8.7e-09 35.4 1.0 3.3 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Afaf PF15339.6 PVD37200.1 - 4.1 7.1 5.9 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Acrosome formation-associated factor DUF1011 PF06237.12 PVD37201.1 - 5.9e-25 87.5 12.5 5.9e-25 87.5 12.5 3.5 5 0 0 5 5 5 1 Protein of unknown function (DUF1011) DUF1011 PF06237.12 PVD37202.1 - 7.9e-27 93.5 11.1 7.9e-27 93.5 11.1 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) DUF5383 PF17355.2 PVD37202.1 - 0.2 12.0 0.9 0.48 10.8 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF1011 PF06237.12 PVD37203.1 - 1.4e-26 92.7 11.2 1.4e-26 92.7 11.2 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) DUF5383 PF17355.2 PVD37203.1 - 0.057 13.8 0.6 0.12 12.7 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) 7tm_1 PF00001.21 PVD37204.1 - 0.00018 20.9 0.1 0.13 11.5 0.1 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 PVD37208.1 - 0.0015 18.5 0.3 0.0015 18.5 0.3 1.4 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 PVD37208.1 - 0.0068 17.3 0.3 0.0086 16.9 0.3 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain m04gp34like PF12216.8 PVD37208.1 - 0.038 13.6 0.4 0.05 13.2 0.4 1.1 1 0 0 1 1 1 0 Immune evasion protein LapA_dom PF06305.11 PVD37208.1 - 0.051 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RIFIN PF02009.16 PVD37208.1 - 0.11 12.4 0.5 0.15 11.9 0.5 1.2 1 0 0 1 1 1 0 Rifin UL45 PF05473.12 PVD37208.1 - 0.12 12.0 0.6 0.17 11.5 0.6 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Orf78 PF06024.12 PVD37208.1 - 0.15 12.4 0.2 0.15 12.4 0.2 1.7 2 0 0 2 2 2 0 Orf78 (ac78) Syndecan PF01034.20 PVD37208.1 - 1.1 9.2 5.6 0.42 10.5 2.9 1.6 2 0 0 2 2 2 0 Syndecan domain Protocadherin PF08374.11 PVD37208.1 - 1.5 8.8 6.1 1.3 9.0 5.2 1.3 1 1 0 1 1 1 0 Protocadherin FGFR3_TM PF18123.1 PVD37208.1 - 2.9 7.5 13.8 3.3 7.3 12.7 1.6 1 1 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Flp1_like PF16982.5 PVD37208.1 - 6.8 6.2 14.3 3.2 7.2 12.3 1.5 1 1 0 1 1 1 0 Putative Flagellin, Flp1-like, domain CUB PF00431.20 PVD37210.1 - 1.1e-12 48.2 0.0 1.8e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 PVD37210.1 - 0.56 10.5 6.8 0.23 11.8 3.4 2.2 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site FXa_inhibition PF14670.6 PVD37211.1 - 0.00013 22.2 2.6 0.00023 21.4 2.6 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SSP160 PF06933.11 PVD37213.1 - 0.52 8.4 13.7 0.66 8.1 13.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF948 PF06103.11 PVD37213.1 - 1.7 8.9 8.8 3.2 8.1 3.0 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syndecan PF01034.20 PVD37214.1 - 4.5e-08 32.9 0.7 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Syndecan domain TMEM154 PF15102.6 PVD37214.1 - 0.00096 19.1 0.8 0.99 9.3 0.0 2.2 2 0 0 2 2 2 2 TMEM154 protein family EphA2_TM PF14575.6 PVD37214.1 - 0.001 19.9 1.3 2.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 PVD37214.1 - 0.0021 17.9 0.4 1.5 8.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) Pox_A14 PF05767.12 PVD37214.1 - 0.0047 17.0 4.1 0.0064 16.6 0.7 2.2 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Cadherin_C_2 PF16492.5 PVD37214.1 - 0.011 16.5 0.8 0.5 11.2 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Gram_pos_anchor PF00746.21 PVD37214.1 - 0.021 14.8 0.4 0.62 10.1 0.3 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Orf78 PF06024.12 PVD37214.1 - 0.05 13.9 0.9 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) LapA_dom PF06305.11 PVD37214.1 - 0.086 12.7 1.4 9.1 6.2 0.8 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF5305 PF17231.2 PVD37214.1 - 0.1 12.0 3.8 1.7 8.0 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) COX6C PF02937.15 PVD37214.1 - 0.12 12.5 4.5 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF2207 PF09972.9 PVD37214.1 - 0.3 9.8 1.8 5.4 5.7 0.8 1.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Cu-oxidase_3 PF07732.15 PVD37215.1 - 2.7e-41 140.3 0.7 1.1e-40 138.4 0.5 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 PVD37215.1 - 8.8e-24 84.4 1.7 3.6e-22 79.2 0.3 2.9 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD37215.1 - 0.0012 18.6 6.8 0.0046 16.7 3.1 2.9 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PVD37216.1 - 7.6e-32 109.9 0.1 2e-31 108.5 0.1 1.6 1 1 0 1 1 1 1 Multicopper oxidase Shisa PF13908.6 PVD37217.1 - 0.0043 17.3 2.7 0.016 15.5 1.7 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 PVD37217.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MRP-L46 PF11788.8 PVD37217.1 - 0.12 13.1 0.3 13 6.6 0.0 2.4 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 YtzH PF14165.6 PVD37217.1 - 0.13 12.6 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 YtzH-like protein EphA2_TM PF14575.6 PVD37217.1 - 0.16 12.8 0.2 0.16 12.8 0.2 2.0 2 2 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD37217.1 - 0.17 11.8 1.2 0.34 10.8 1.2 1.4 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 PVD37217.1 - 2.9 8.4 4.6 9.4 6.7 1.0 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Exonuc_VII_L PF02601.15 PVD37218.1 - 0.046 13.3 1.0 0.051 13.2 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YceG PF02618.16 PVD37218.1 - 0.09 12.3 0.3 0.12 11.9 0.3 1.2 1 1 0 1 1 1 0 YceG-like family DUF1635 PF07795.11 PVD37218.1 - 0.12 12.2 3.0 0.1 12.4 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SCAN PF02023.17 PVD37219.1 - 2.2e-13 49.8 0.1 6.2e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 PVD37219.1 - 2.6e-07 30.4 2.4 2.6e-07 30.4 2.4 2.2 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 PVD37219.1 - 0.035 14.7 0.0 0.085 13.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 PVD37219.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Borrelia_P83 PF05262.11 PVD37219.1 - 4.2 5.7 19.5 6 5.2 19.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RNase_H PF00075.24 PVD37220.1 - 5e-13 49.5 0.0 1.5e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 PVD37220.1 - 0.0029 17.4 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like EGF_CA PF07645.15 PVD37221.1 - 9.9e-21 73.7 32.2 5e-10 39.4 4.7 3.6 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD37221.1 - 1.4e-20 73.2 37.5 1.9e-09 37.6 7.7 3.7 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site CUB PF00431.20 PVD37221.1 - 8.3e-19 68.0 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain cEGF PF12662.7 PVD37221.1 - 1.2e-15 57.0 17.9 6.6e-09 35.5 2.5 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.27 PVD37221.1 - 1.9e-05 24.9 32.9 0.013 15.7 6.6 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 PVD37221.1 - 0.00048 20.3 27.5 0.03 14.5 5.9 3.9 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 PVD37221.1 - 0.0023 18.5 25.4 0.0058 17.2 8.2 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF UPF0560 PF10577.9 PVD37221.1 - 0.0034 16.0 0.0 0.0045 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 Tweety PF04906.13 PVD37221.1 - 0.0055 15.4 0.2 0.0077 14.9 0.2 1.1 1 0 0 1 1 1 1 Tweety TMEM52 PF14979.6 PVD37221.1 - 0.0065 16.4 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Transmembrane 52 Mid2 PF04478.12 PVD37221.1 - 0.013 15.4 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 PVD37221.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Plasmod_Pvs28 PF06247.11 PVD37221.1 - 0.028 14.7 2.9 0.028 14.7 2.9 4.0 3 1 1 4 4 3 0 Pvs28 EGF domain Dimer_Tnp_hAT PF05699.14 PVD37222.1 - 8.8e-06 25.4 0.4 2.2e-05 24.2 0.3 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region EGF_CA PF07645.15 PVD37225.1 - 1.5e-20 73.1 32.2 5.7e-10 39.2 4.7 3.5 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD37225.1 - 2.2e-20 72.6 37.5 2.1e-09 37.5 7.7 3.7 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site CUB PF00431.20 PVD37225.1 - 1e-18 67.7 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 CUB domain cEGF PF12662.7 PVD37225.1 - 1.9e-15 56.5 17.9 7.5e-09 35.4 2.5 3.7 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.27 PVD37225.1 - 2.8e-05 24.3 32.9 0.015 15.6 6.6 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 PVD37225.1 - 0.00073 19.7 27.5 0.034 14.3 5.9 3.8 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 PVD37225.1 - 0.0035 17.9 25.4 0.0065 17.1 8.2 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF UPF0560 PF10577.9 PVD37225.1 - 0.0035 15.9 0.0 0.0044 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 Tweety PF04906.13 PVD37225.1 - 0.0063 15.2 0.2 0.0091 14.7 0.2 1.1 1 0 0 1 1 1 1 Tweety TMEM52 PF14979.6 PVD37225.1 - 0.0072 16.3 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 Transmembrane 52 Mid2 PF04478.12 PVD37225.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 PVD37225.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Plasmod_Pvs28 PF06247.11 PVD37225.1 - 0.03 14.6 2.8 0.03 14.6 2.8 3.9 3 1 1 4 4 3 0 Pvs28 EGF domain TSP_1 PF00090.19 PVD37228.1 - 4.3e-08 33.2 116.1 7.8e-06 26.0 4.2 13.3 11 2 0 11 11 11 9 Thrombospondin type 1 domain TSP_1 PF00090.19 PVD37229.1 - 5.8e-29 100.1 86.6 1.3e-11 44.5 6.2 9.0 8 0 0 8 8 8 6 Thrombospondin type 1 domain Antimicrobial_6 PF08036.11 PVD37229.1 - 0.019 15.0 5.2 1.2 9.2 0.5 4.2 3 0 0 3 3 3 0 Diapausin family of antimicrobial peptide MgtE_N PF03448.17 PVD37231.1 - 1e-27 96.7 23.9 3.6e-08 33.9 1.1 5.9 3 3 3 6 6 6 6 MgtE intracellular N domain C-C_Bond_Lyase PF15617.6 PVD37231.1 - 2.1e-05 23.9 2.1 0.076 12.2 0.1 2.3 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3194 PF11419.8 PVD37231.1 - 0.011 16.1 2.5 82 3.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3194) Rio2_N PF09202.11 PVD37231.1 - 0.092 13.0 5.7 6.3 7.1 0.0 4.5 3 2 2 5 5 5 0 Rio2, N-terminal FYRC PF05965.14 PVD37231.1 - 0.16 12.2 0.7 16 5.8 0.1 2.9 2 0 0 2 2 2 0 F/Y rich C-terminus DUF4494 PF14902.6 PVD37231.1 - 0.18 11.6 0.0 1e+02 2.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4494) FliG_C PF01706.16 PVD37231.1 - 0.31 11.2 11.6 17 5.7 0.5 5.4 5 1 1 6 6 6 0 FliG C-terminal domain HTH_20 PF12840.7 PVD37231.1 - 0.35 10.9 6.3 9 6.4 0.2 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain DIL PF01843.19 PVD37231.1 - 0.83 10.0 21.8 2.2 8.6 0.6 6.9 3 3 3 6 6 6 0 DIL domain DUF1323 PF07037.11 PVD37231.1 - 1.7 9.1 11.2 78 3.7 0.1 5.4 4 1 1 5 5 5 0 Putative transcription regulator (DUF1323) Se-cys_synth_N PF12390.8 PVD37231.1 - 2.9 8.2 12.7 29 5.0 0.5 5.1 4 0 0 4 4 4 0 Selenocysteine synthase N terminal MgtE_N PF03448.17 PVD37232.1 - 5e-19 68.8 8.3 1.4e-10 41.7 0.6 2.9 1 1 2 3 3 3 3 MgtE intracellular N domain FliG_N PF14842.6 PVD37232.1 - 0.0036 17.8 1.1 37 4.9 0.0 4.1 1 1 1 4 4 4 1 FliG N-terminal domain FliG_C PF01706.16 PVD37232.1 - 0.049 13.8 1.7 4.6 7.5 0.1 3.1 1 1 3 4 4 4 0 FliG C-terminal domain DUF1877 PF08974.10 PVD37232.1 - 0.09 12.9 0.0 51 3.9 0.0 3.2 3 2 1 4 4 4 0 Domain of unknown function (DUF1877) OppC_N PF12911.7 PVD37233.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Acyl_transf_3 PF01757.22 PVD37234.1 - 1.4e-18 67.1 26.5 2e-18 66.6 26.5 1.1 1 0 0 1 1 1 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 PVD37234.1 - 0.058 13.3 0.8 0.058 13.3 0.8 3.0 4 0 0 4 4 4 0 TB2/DP1, HVA22 family Acyl_transf_3 PF01757.22 PVD37236.1 - 7.2e-18 64.7 40.8 1.1e-17 64.2 40.8 1.2 1 0 0 1 1 1 1 Acyltransferase family Baculo_11_kDa PF06143.11 PVD37236.1 - 1.9 8.1 5.3 20 4.8 0.2 2.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family SH3_1 PF00018.28 PVD37237.1 - 3.4e-12 45.8 0.0 5.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD37237.1 - 3.5e-11 42.8 0.0 7.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nebulin PF00880.18 PVD37237.1 - 5.3e-07 29.4 0.4 0.0035 17.2 0.1 2.3 2 0 0 2 2 2 2 Nebulin repeat SH3_2 PF07653.17 PVD37237.1 - 3.5e-05 23.4 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L14 PF00238.19 PVD37238.1 - 1.9e-34 118.4 0.3 2.2e-34 118.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SKICH PF17751.1 PVD37239.1 - 4.2e-32 110.8 0.0 1.2e-31 109.3 0.0 1.9 1 0 0 1 1 1 1 SKICH domain zf-C2H2_9 PF16293.5 PVD37239.1 - 0.00083 19.1 2.1 0.077 12.8 0.1 3.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) ATG16 PF08614.11 PVD37239.1 - 0.006 16.8 18.6 0.006 16.8 18.6 4.0 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) zf-Di19 PF05605.12 PVD37239.1 - 0.1 12.9 3.2 0.42 10.9 3.2 2.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 PVD37239.1 - 0.3 11.6 14.0 2.6 8.6 0.1 3.9 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain EGF_CA PF07645.15 PVD37240.1 - 6.1e-12 45.6 41.8 2.4e-06 27.6 11.4 3.5 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF PF00008.27 PVD37240.1 - 5.4e-08 33.0 38.3 2.6e-06 27.6 8.3 3.8 3 0 0 3 3 3 3 EGF-like domain cEGF PF12662.7 PVD37240.1 - 0.0053 16.7 0.2 0.0053 16.7 0.2 3.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like MLANA PF14991.6 PVD37240.1 - 0.0066 16.7 0.1 0.085 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein melan-A EGF_3 PF12947.7 PVD37240.1 - 0.025 14.8 37.1 0.2 11.9 9.1 4.3 3 1 0 3 3 3 0 EGF domain TMEM132D_C PF15706.5 PVD37240.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Rax2 PF12768.7 PVD37240.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity hEGF PF12661.7 PVD37240.1 - 5.5 7.8 33.3 0.29 11.8 4.8 4.8 4 1 0 4 4 4 0 Human growth factor-like EGF FXa_inhibition PF14670.6 PVD37240.1 - 5.7 7.3 39.3 3.5 8.0 4.3 3.9 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 PVD37240.1 - 5.7 7.4 37.8 2.2 8.7 6.2 3.9 3 0 0 3 3 3 0 EGF-like domain EGF_CA PF07645.15 PVD37241.1 - 9.5e-13 48.1 44.2 2.1e-08 34.2 11.6 3.6 3 0 0 3 3 3 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD37241.1 - 0.0027 17.9 32.9 0.25 11.6 7.2 3.7 1 1 2 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 PVD37241.1 - 0.0036 17.6 34.6 0.054 13.8 3.4 3.9 3 1 0 3 3 3 2 EGF-like domain cEGF PF12662.7 PVD37241.1 - 0.021 14.8 20.0 0.12 12.3 2.7 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD37241.1 - 0.029 14.6 9.2 0.029 14.6 9.2 4.7 5 0 0 5 5 5 0 EGF domain hEGF PF12661.7 PVD37241.1 - 0.036 14.7 28.1 0.069 13.8 0.9 4.6 3 2 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 PVD37241.1 - 0.18 12.2 43.2 0.16 12.4 12.6 3.7 2 1 1 3 3 3 0 EGF-like domain DUF4674 PF15719.5 PVD37241.1 - 0.38 10.8 4.4 0.84 9.6 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Laminin_G_2 PF02210.24 PVD37242.1 - 1.6e-76 254.9 11.7 1.8e-23 83.4 1.2 4.3 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 PVD37242.1 - 7e-43 146.0 3.6 1.1e-15 57.9 0.1 4.9 4 1 0 4 4 4 4 Laminin G domain F5_F8_type_C PF00754.25 PVD37242.1 - 2.9e-25 88.8 1.1 1.3e-24 86.8 0.1 2.7 3 0 0 3 3 3 1 F5/8 type C domain Laminin_G_3 PF13385.6 PVD37242.1 - 2.3e-07 31.1 4.9 0.01 16.0 0.0 4.1 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 PVD37242.1 - 0.00011 22.4 9.3 0.00011 22.4 9.3 2.5 2 0 0 2 2 2 1 EGF-like domain EF-hand_7 PF13499.6 PVD37243.1 - 4.3e-14 52.7 1.3 1.9e-07 31.4 0.5 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD37243.1 - 9.8e-11 40.7 2.2 0.00045 19.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PVD37243.1 - 7.6e-10 37.6 5.0 0.0011 18.4 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PVD37243.1 - 0.0001 22.1 2.5 0.0036 17.1 0.1 3.6 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.6 PVD37243.1 - 0.00031 21.0 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain DUF4497 PF14924.6 PVD37243.1 - 0.062 13.8 0.0 7.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) DUF3911 PF13050.6 PVD37243.1 - 0.083 13.0 0.1 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) EF-hand_5 PF13202.6 PVD37243.1 - 0.091 12.3 1.7 9.1 6.0 0.1 3.4 3 0 0 3 3 3 0 EF hand DUF3349 PF11829.8 PVD37243.1 - 0.2 12.4 0.0 6.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_7 PF13499.6 PVD37244.1 - 5.9e-14 52.3 3.5 6.2e-08 33.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD37244.1 - 4.6e-11 41.7 3.3 0.00021 20.9 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PVD37244.1 - 3.1e-10 38.8 4.2 0.00043 19.6 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 PVD37244.1 - 4.2e-05 22.9 7.6 0.0013 18.1 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PVD37244.1 - 0.0011 18.7 2.3 1.7 8.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 PVD37244.1 - 0.0031 17.4 1.7 4.7 7.2 0.1 3.1 3 0 0 3 3 3 2 EF hand DUF5579 PF17742.1 PVD37245.1 - 0.038 13.6 0.1 0.038 13.6 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5579) 2-Hacid_dh_C PF02826.19 PVD37248.1 - 1.8e-54 183.8 0.0 9.2e-28 96.8 0.0 3.2 3 0 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PVD37248.1 - 1.3e-06 28.5 0.1 0.013 15.6 0.0 3.4 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 PVD37248.1 - 0.00014 22.1 2.6 0.24 11.7 0.2 3.8 2 2 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 PVD37248.1 - 0.00016 21.9 0.1 0.067 13.3 0.0 2.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 PVD37248.1 - 0.0005 20.5 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding F420_oxidored PF03807.17 PVD37248.1 - 0.00092 19.7 0.2 0.069 13.7 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 PVD37248.1 - 0.0036 16.6 0.2 0.28 10.4 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 PVD37248.1 - 0.0064 16.6 0.1 0.42 10.7 0.1 2.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 PVD37248.1 - 0.0084 16.0 0.2 1.3 8.9 0.0 2.7 2 1 1 3 3 3 1 NAD(P)H-binding ELFV_dehydrog PF00208.21 PVD37248.1 - 0.022 14.5 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh PF00389.30 PVD37248.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 PVD37248.1 - 0.058 13.5 0.5 3.1 7.8 0.0 2.5 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TraB PF01963.17 PVD37248.1 - 0.062 13.2 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 TraB family ThiF PF00899.21 PVD37248.1 - 0.091 12.1 1.4 5 6.4 0.0 3.0 4 0 0 4 4 4 0 ThiF family NAD_Gly3P_dh_N PF01210.23 PVD37248.1 - 0.17 11.8 5.7 11 6.0 0.1 4.3 5 1 0 5 5 5 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 PVD37248.1 - 0.18 12.1 0.1 3 8.2 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 PVD37249.1 - 1.5e-26 92.8 0.1 1e-13 51.1 0.0 2.1 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PVD37249.1 - 0.00064 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 PVD37249.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 PVD37249.1 - 0.015 15.5 0.1 0.02 15.1 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.21 PVD37249.1 - 0.017 14.8 0.2 0.031 14.0 0.2 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 PVD37249.1 - 0.027 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 PVD37249.1 - 0.051 13.8 0.2 0.16 12.2 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 PVD37249.1 - 0.11 13.1 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Myosin_head PF00063.21 PVD37250.1 - 2.7e-152 508.4 2.8 7.5e-152 506.9 2.8 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 PVD37250.1 - 2e-28 99.3 2.9 1.9e-25 89.5 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD37250.1 - 2.1e-12 47.4 2.7 2.1e-12 47.4 2.7 2.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD37250.1 - 2.4e-06 27.6 0.5 7.7e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 AAA_22 PF13401.6 PVD37250.1 - 0.0061 16.8 0.3 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD37250.1 - 0.011 15.5 0.1 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Afi1 PF07792.12 PVD37250.1 - 0.63 10.5 4.0 2.4 8.6 4.0 1.9 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 PVD37250.1 - 0.72 9.6 5.6 3.1 7.5 4.8 2.4 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 PVD37250.1 - 3.8 7.7 8.8 2 8.6 3.7 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 PVD37250.1 - 5.2 6.4 10.1 0.55 9.6 3.9 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein tRNA-synt_1g PF09334.11 PVD37251.1 - 8.6e-149 495.5 0.0 1.2e-148 495.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) GST_N_5 PF18485.1 PVD37251.1 - 3.5e-19 68.9 0.0 9.2e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WHEP-TRS PF00458.20 PVD37251.1 - 1.2e-12 47.8 4.2 2.6e-12 46.7 4.2 1.6 1 0 0 1 1 1 1 WHEP-TRS domain GST_C_2 PF13410.6 PVD37251.1 - 2.1e-10 40.5 0.8 4.3e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.22 PVD37251.1 - 1.2e-08 33.7 0.0 0.0037 15.6 0.1 2.9 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C PF00043.25 PVD37251.1 - 2.1e-06 27.8 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PVD37251.1 - 1.2e-05 25.0 0.0 3.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD37251.1 - 3.9e-05 23.8 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.13 PVD37251.1 - 0.00013 21.9 0.1 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA zinc-ribbons_6 PF07191.12 PVD37251.1 - 2.6 8.1 6.8 2.6 8.1 0.5 2.3 1 1 0 2 2 2 0 zinc-ribbons C1_1 PF00130.22 PVD37251.1 - 9.7 6.2 8.7 18 5.3 1.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RVT_1 PF00078.27 PVD37252.1 - 0.046 13.2 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Colipase-like PF15083.6 PVD37253.1 - 0.007 16.5 0.8 0.0096 16.0 0.8 1.2 1 0 0 1 1 1 1 Colipase-like MFS_1 PF07690.16 PVD37254.1 - 3.9e-17 62.2 33.9 4.1e-17 62.1 33.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2614 PF11023.8 PVD37254.1 - 0.13 12.3 3.0 0.45 10.6 3.0 1.9 1 0 0 1 1 1 0 Zinc-ribbon containing domain RAP PF08373.10 PVD37255.1 - 2.7e-06 27.4 0.0 7.1e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 RAP domain Bax1-I PF01027.20 PVD37256.1 - 7.3e-46 156.6 30.7 7.3e-46 156.6 30.7 2.7 3 0 0 3 3 3 1 Inhibitor of apoptosis-promoting Bax1 zinc_ribbon_10 PF10058.9 PVD37256.1 - 7.8e-20 70.3 1.5 1.5e-19 69.4 1.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Esterase_phd PF10503.9 PVD37256.1 - 3.9e-14 52.7 18.5 7.9e-05 22.2 7.4 4.2 3 1 0 3 3 3 3 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 PVD37256.1 - 0.0087 15.9 0.9 3.6 7.4 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold BaxI_1 PF12811.7 PVD37256.1 - 0.0093 15.5 21.5 0.022 14.3 21.5 1.6 1 0 0 1 1 1 1 Bax inhibitor 1 like BTB PF00651.31 PVD37256.1 - 0.019 15.2 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 BTB/POZ domain DUF2518 PF10726.9 PVD37256.1 - 1.5 8.5 5.8 3.5 7.3 5.8 1.5 1 0 0 1 1 1 0 Protein of function (DUF2518) DUF2070 PF09843.9 PVD37256.1 - 7.2 4.8 22.5 13 3.9 22.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PID_2 PF14719.6 PVD37257.1 - 1.6e-05 24.8 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 PVD37257.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Apt1 PF10351.9 PVD37257.1 - 0.015 14.1 3.8 0.022 13.6 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 PVD37257.1 - 0.49 10.1 7.4 0.88 9.2 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 PVD37257.1 - 0.79 7.9 6.0 0.92 7.7 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4674 PF15719.5 PVD37257.1 - 1.7 8.6 8.0 3.5 7.6 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Homeodomain PF00046.29 PVD37258.1 - 9.5e-23 79.8 7.1 1.4e-22 79.3 7.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD37258.1 - 2.2 8.2 4.8 0.56 10.1 0.3 2.3 2 1 1 3 3 3 0 Homeobox KN domain Homeodomain PF00046.29 PVD37260.1 - 2.6e-23 81.6 8.6 3.8e-23 81.1 8.6 1.2 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 PVD37260.1 - 0.016 15.0 0.4 0.033 14.0 0.2 1.5 1 1 0 1 1 1 0 Homeodomain-like domain Homeobox_KN PF05920.11 PVD37260.1 - 0.046 13.6 0.9 0.11 12.4 0.5 1.8 1 1 1 2 2 2 0 Homeobox KN domain Cyclin_N PF00134.23 PVD37261.1 - 8.8e-20 70.7 2.6 8e-18 64.4 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DHODB_Fe-S_bind PF10418.9 PVD37261.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF4919 PF16266.5 PVD37261.1 - 0.44 10.5 3.2 0.2 11.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) zf-C3Hc3H PF13891.6 PVD37262.1 - 5.4e-17 61.9 6.1 5.4e-17 61.9 6.1 1.8 2 0 0 2 2 2 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 PVD37262.1 - 0.035 13.9 0.3 0.035 13.9 0.3 3.2 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein Hat1_N PF10394.9 PVD37263.1 - 3.9e-42 144.2 0.2 3e-41 141.3 0.1 2.1 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 PVD37263.1 - 0.00061 19.5 0.2 0.0011 18.7 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 PVD37263.1 - 0.0073 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PVD37263.1 - 0.012 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PVD37263.1 - 0.044 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fe-S_biosyn PF01521.20 PVD37263.1 - 0.061 13.5 0.4 6 7.1 0.0 3.0 3 0 0 3 3 3 0 Iron-sulphur cluster biosynthesis DENN PF02141.21 PVD37263.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain Mito_carr PF00153.27 PVD37264.1 - 4.8e-70 231.6 0.2 3.8e-25 87.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 PVD37264.1 - 1.3e-17 61.9 1.5 2.5e-05 23.5 0.1 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD37264.1 - 4e-15 54.4 4.4 5.8e-05 22.7 0.1 5.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 PVD37264.1 - 2.5e-14 53.5 5.9 0.00062 20.2 0.4 5.4 3 3 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PVD37264.1 - 1.1e-08 34.8 2.5 0.0054 16.5 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD37264.1 - 1e-07 31.1 2.3 0.013 15.0 0.1 4.1 4 0 0 4 4 4 2 EF hand Pyridoxal_deC PF00282.19 PVD37265.1 - 8.9e-104 347.2 0.0 1.1e-103 346.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PVD37265.1 - 1.6e-07 30.9 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 PVD37265.1 - 1.3e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 PVD37265.1 - 0.21 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS fn3 PF00041.21 PVD37268.1 - 6.2e-25 87.4 3.8 2.8e-09 37.2 0.0 4.3 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD37268.1 - 0.00043 20.8 4.0 2.4 8.8 0.0 3.8 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 PVD37268.1 - 0.049 14.0 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Ig_3 PF13927.6 PVD37269.1 - 7e-05 23.4 0.5 0.00014 22.4 0.2 1.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 PVD37269.1 - 9.1e-05 22.7 0.4 0.00014 22.1 0.4 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 PVD37270.1 - 0.029 15.0 0.0 0.056 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Cohesin PF00963.18 PVD37270.1 - 0.061 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Cohesin domain Ig_3 PF13927.6 PVD37272.1 - 1.3e-58 195.5 11.8 8.3e-13 48.7 0.1 7.5 8 0 0 8 8 7 5 Immunoglobulin domain I-set PF07679.16 PVD37272.1 - 3.7e-54 180.7 0.0 1.3e-11 44.4 0.0 6.2 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD37272.1 - 1.3e-35 121.5 5.9 5.9e-10 39.4 0.1 5.7 4 1 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 PVD37272.1 - 1.1e-32 112.0 4.0 5.9e-09 36.0 0.0 6.7 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 PVD37272.1 - 3e-24 85.2 5.4 1.4e-11 44.6 0.3 4.6 4 0 0 4 4 4 3 Fibronectin type III domain V-set PF07686.17 PVD37272.1 - 1.1e-17 64.2 13.1 0.00043 20.4 0.1 10.8 7 4 2 10 10 10 3 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD37272.1 - 7.4e-08 31.8 1.6 2.3 7.8 0.0 6.1 6 0 0 6 6 6 2 Immunoglobulin domain Ig_5 PF16681.5 PVD37272.1 - 1.9e-06 28.2 0.0 3.8 8.0 0.0 4.8 5 0 0 5 5 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD37272.1 - 1.3e-05 25.3 0.0 0.21 11.9 0.0 4.0 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 PVD37272.1 - 4.7e-05 23.3 1.7 0.7 10.0 0.0 4.8 4 1 0 4 4 4 1 C17orf99 Ig domain C2-set_2 PF08205.12 PVD37272.1 - 8.6e-05 22.5 0.2 0.72 10.0 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 PVD37272.1 - 0.00097 19.3 0.0 3 8.1 0.0 4.7 4 1 1 5 5 5 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 PVD37272.1 - 0.0023 18.0 0.8 12 6.0 0.0 4.8 6 0 0 6 6 6 0 Izumo-like Immunoglobulin domain SusE PF14292.6 PVD37272.1 - 0.022 15.0 1.5 0.23 11.7 0.2 2.6 2 0 0 2 2 2 0 SusE outer membrane protein Pur_ac_phosph_N PF16656.5 PVD37272.1 - 0.057 14.0 0.3 0.057 14.0 0.3 4.3 5 0 0 5 5 3 0 Purple acid Phosphatase, N-terminal domain BiPBP_C PF06832.12 PVD37272.1 - 0.079 13.0 0.0 8 6.6 0.0 3.1 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family PAP2 PF01569.21 PVD37273.1 - 1.9e-17 63.3 0.1 3e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 PVD37273.1 - 0.0011 19.5 1.3 0.0024 18.4 1.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily C-terminal DUF3990 PF13151.6 PVD37273.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) aGPT-Pplase3 PF18746.1 PVD37273.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 CBM_14 PF01607.24 PVD37275.1 - 1.2e-13 51.0 3.2 1.9e-13 50.3 3.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SOCS_box PF07525.16 PVD37276.1 - 6.1e-05 23.3 2.6 0.0002 21.6 2.6 1.9 1 0 0 1 1 1 1 SOCS box Lenti_VIF_2 PF07401.12 PVD37276.1 - 0.0041 16.5 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Bovine Lentivirus VIF protein Med10 PF09748.9 PVD37276.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF493 PF04359.14 PVD37276.1 - 0.044 14.4 0.0 0.41 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF493) MTES_1575 PF18741.1 PVD37276.1 - 0.09 13.0 0.1 0.29 11.3 0.1 1.9 1 0 0 1 1 1 0 REase_MTES_1575 HSP70 PF00012.20 PVD37277.1 - 1.6e-201 670.6 9.7 1.8e-201 670.4 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD37277.1 - 7.2e-16 57.9 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 PVD37277.1 - 0.0019 18.0 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PVD37277.1 - 0.028 13.7 0.2 0.074 12.3 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Zincin_2 PF10103.9 PVD37277.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase MetOD2 PF18548.1 PVD37277.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.5 2 0 0 2 2 2 0 Metanogen output domain 2 DNApol_Exo PF18136.1 PVD37277.1 - 0.52 9.4 3.3 1 8.4 3.3 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain AAA_11 PF13086.6 PVD37277.1 - 6.2 6.5 8.2 16 5.2 5.6 2.2 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 PVD37278.1 - 2.7e-101 337.3 0.1 1.1e-100 335.3 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 PVD37278.1 - 1e-34 119.1 0.9 2.1e-34 118.1 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PVD37278.1 - 1.4e-28 99.1 0.5 4.1e-28 97.6 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 PVD37278.1 - 1e-18 67.5 0.1 1e-18 67.5 0.1 2.1 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 PVD37278.1 - 3.4e-16 59.7 0.1 1e-15 58.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PVD37278.1 - 2.2e-07 30.5 0.0 1.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PVD37278.1 - 4.9e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD37278.1 - 1.5e-05 25.0 0.3 9.2e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PVD37278.1 - 0.0032 17.2 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 PVD37278.1 - 0.36 11.5 3.9 0.42 11.3 0.2 3.1 4 1 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal NOG1_N PF17835.1 PVD37279.1 - 3.5e-54 183.1 1.7 3.5e-54 183.1 1.7 2.5 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 PVD37279.1 - 1.6e-26 91.8 0.3 3.4e-26 90.8 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 PVD37279.1 - 7e-25 86.8 4.5 7e-25 86.8 4.5 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 PVD37279.1 - 6.5e-19 68.1 0.0 3.6e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD37279.1 - 8.7e-11 41.6 0.0 3.2e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PVD37279.1 - 2e-05 24.6 0.0 0.098 12.6 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PVD37279.1 - 0.0013 18.8 4.0 0.88 9.6 0.0 3.3 2 2 1 3 3 3 2 Dynamin family AIG1 PF04548.16 PVD37279.1 - 0.002 17.5 1.0 0.0087 15.4 0.0 2.4 3 0 0 3 3 3 1 AIG1 family Arf PF00025.21 PVD37279.1 - 0.0026 17.2 0.0 0.081 12.4 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 PVD37279.1 - 0.0052 17.0 0.0 0.15 12.3 0.0 2.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD37279.1 - 0.013 15.1 0.0 0.041 13.5 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_18 PF13238.6 PVD37279.1 - 0.03 14.9 5.5 6 7.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain SRPRB PF09439.10 PVD37279.1 - 0.091 12.2 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RGS_DHEX PF18148.1 PVD37279.1 - 1.8 8.7 4.5 8.2 6.6 1.2 2.8 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Annexin PF00191.20 PVD37280.1 - 4.6e-169 548.7 23.3 5.5e-27 93.6 0.2 8.3 8 0 0 8 8 8 8 Annexin CHB_HEX_C_1 PF13290.6 PVD37280.1 - 1.2e-09 38.0 0.0 2.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 PVD37280.1 - 2.2e-09 37.4 0.0 5.8e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Fn3 associated Myb_DNA-bind_7 PF15963.5 PVD37280.1 - 2.9e-05 23.9 0.7 4.3 7.3 0.0 5.5 6 0 0 6 6 6 1 Myb DNA-binding like Levi_coat PF01819.17 PVD37280.1 - 0.001 19.1 0.0 10 6.1 0.0 3.6 3 0 0 3 3 3 2 Levivirus coat protein Sigma70_ner PF04546.13 PVD37280.1 - 0.012 15.5 7.6 0.016 15.1 0.2 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region RRM_1 PF00076.22 PVD37281.1 - 9.4e-10 38.2 0.0 2.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP_assoc PF03828.19 PVD37281.1 - 7.9e-07 29.2 0.1 2.9e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase RL PF17797.1 PVD37281.1 - 4.3e-05 23.4 0.1 9.7e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 RL domain PAP_central PF04928.17 PVD37281.1 - 6.1e-05 22.1 0.0 0.00025 20.1 0.0 2.0 1 1 0 1 1 1 1 Poly(A) polymerase central domain RRM_5 PF13893.6 PVD37281.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COG2 PF06148.11 PVD37281.1 - 0.093 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Nrap_D2 PF17403.2 PVD37281.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 PVD37281.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Lectin_C PF00059.21 PVD37282.1 - 9.5e-17 61.7 0.0 1.5e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF2793 PF10983.8 PVD37282.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Lectin_C PF00059.21 PVD37283.1 - 7.1e-30 103.9 0.0 9.5e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD37283.1 - 0.035 13.7 0.1 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like UPF0061 PF02696.14 PVD37284.1 - 7e-118 394.4 0.0 1.6e-117 393.2 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Galanin PF01296.18 PVD37287.1 - 0.088 12.8 10.9 2.7 8.1 0.2 4.1 2 1 2 4 4 4 0 Galanin SelP_N PF04592.14 PVD37288.1 - 0.57 9.5 5.9 0.95 8.8 5.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Homeodomain PF00046.29 PVD37290.1 - 1.3e-22 79.4 9.3 1.3e-22 79.4 9.3 1.9 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 PVD37290.1 - 0.0089 15.9 0.8 0.021 14.7 0.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF2209 PF09974.9 PVD37290.1 - 0.034 14.5 0.1 0.057 13.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 PVD37291.1 - 2.8e-22 78.3 9.2 3.8e-22 77.9 9.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD37291.1 - 0.1 12.5 1.0 0.17 11.8 1.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 PVD37291.1 - 0.15 12.4 0.1 0.22 11.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 PVD37294.1 - 3.2e-21 74.9 5.0 5.1e-21 74.3 5.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD37294.1 - 0.13 12.2 0.3 0.28 11.1 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain LRR_8 PF13855.6 PVD37295.1 - 2.8e-17 62.2 8.3 3.1e-15 55.7 3.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD37295.1 - 9.6e-11 41.8 11.0 4.4e-07 30.1 1.6 3.2 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD37295.1 - 1e-05 25.4 6.9 0.22 12.2 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 PVD37295.1 - 4.4e-05 23.4 0.1 0.00021 21.2 0.0 1.9 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PVD37295.1 - 0.0013 18.6 10.1 0.31 11.2 1.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat DUF3439 PF11921.8 PVD37295.1 - 0.0027 17.7 2.9 0.0044 17.0 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF4713 PF15831.5 PVD37295.1 - 0.012 16.0 0.4 0.027 14.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF4501 PF14946.6 PVD37295.1 - 0.07 13.2 0.7 0.098 12.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Orf78 PF06024.12 PVD37295.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) LRR_9 PF14580.6 PVD37295.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Renin_r PF07850.14 PVD37295.1 - 0.12 13.0 0.3 0.18 12.4 0.3 1.2 1 0 0 1 1 1 0 Renin receptor-like protein Stevor PF17410.2 PVD37295.1 - 0.24 10.9 0.2 0.34 10.4 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SSP160 PF06933.11 PVD37295.1 - 0.57 8.3 8.0 0.74 8.0 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LRR_8 PF13855.6 PVD37296.1 - 6.7e-27 93.0 25.5 7.2e-08 32.1 5.2 5.4 4 1 0 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PVD37296.1 - 1.5e-18 66.5 30.6 0.00019 21.7 0.2 7.3 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD37296.1 - 0.00013 21.5 11.1 0.036 13.6 2.1 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PVD37296.1 - 0.0025 18.1 33.1 6.1 7.8 2.4 9.2 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD37296.1 - 0.0025 17.7 23.1 5 7.4 0.1 8.2 9 1 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.6 PVD37297.1 - 1.7e-13 50.1 7.9 1.5e-06 27.8 0.0 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PVD37297.1 - 1.2e-05 25.6 2.5 0.03 14.7 0.4 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD37297.1 - 0.00042 20.3 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD37297.1 - 0.0013 19.0 0.3 46 5.1 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD37298.1 - 7.7e-09 35.2 6.8 5.1e-06 26.1 2.9 2.5 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD37298.1 - 3.1e-08 33.8 3.3 9.2e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD37298.1 - 0.00063 19.6 0.2 5.8 7.2 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat DUF4571 PF15137.6 PVD37298.1 - 0.043 13.4 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) AIM24 PF01987.17 PVD37298.1 - 0.044 13.6 0.1 0.055 13.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 LRR_9 PF14580.6 PVD37298.1 - 0.046 13.2 0.1 0.096 12.2 0.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 PVD37298.1 - 0.1 13.2 3.9 15 6.6 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRRNT PF01462.18 PVD37298.1 - 0.12 12.0 1.0 0.69 9.6 0.5 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain FAF PF11250.8 PVD37299.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Fantastic Four meristem regulator Homeodomain PF00046.29 PVD37302.1 - 9.9e-23 79.8 4.8 1.3e-22 79.4 4.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD37302.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Homeobox KN domain Antifungal_prot PF11402.8 PVD37305.1 - 0.00033 20.8 0.2 0.00043 20.5 0.2 1.1 1 0 0 1 1 1 1 Antifungal protein RRM_1 PF00076.22 PVD37307.1 - 1.6e-37 127.1 0.1 3e-18 65.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD37307.1 - 3.7e-11 43.0 0.3 2.1e-05 24.5 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD37307.1 - 0.0031 17.5 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PVD37307.1 - 0.0086 16.1 0.1 0.083 12.9 0.1 2.1 2 0 0 2 2 2 1 RNA binding motif RVT_1 PF00078.27 PVD37308.1 - 5.1e-28 98.1 0.0 8.4e-28 97.4 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_5 PF12688.7 PVD37308.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat Myosin_head PF00063.21 PVD37309.1 - 1.7e-245 816.4 0.0 2.1e-245 816.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PVD37309.1 - 1.4e-34 119.5 0.3 2.8e-34 118.5 0.3 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 PVD37309.1 - 1.3e-09 37.0 36.6 0.0005 19.6 0.5 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_16 PF13191.6 PVD37309.1 - 0.022 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ldl_recept_a PF00057.18 PVD37310.1 - 5.2e-26 90.6 44.2 1.8e-06 28.0 0.9 7.2 7 0 0 7 7 7 5 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD37310.1 - 1.8e-10 40.4 8.2 0.00015 21.5 3.8 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PVD37310.1 - 4.1e-09 36.6 7.7 4.5e-06 26.9 0.5 4.2 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD37310.1 - 2.6e-06 27.2 3.2 2.3 9.1 0.0 6.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD37310.1 - 0.00014 21.7 3.9 3.1 8.1 0.1 5.3 6 0 0 6 6 6 2 Leucine Rich repeat 7tm_1 PF00001.21 PVD37310.1 - 0.0018 17.7 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NVEALA PF14055.6 PVD37310.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 NVEALA protein RabGAP-TBC PF00566.18 PVD37311.1 - 7e-26 91.2 9.2 4.8e-13 49.3 2.7 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain AOX PF01786.17 PVD37312.1 - 2.5e-145 481.6 6.7 1.1e-92 309.5 1.0 2.1 2 0 0 2 2 2 2 Alternative oxidase B12D PF06522.11 PVD37312.1 - 3e-21 75.0 0.0 8.2e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF551 PF04448.12 PVD37312.1 - 0.049 14.6 0.1 0.76 10.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF551) Peptidase_S66C PF17676.1 PVD37312.1 - 0.067 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Serpin PF00079.20 PVD37313.1 - 2.2e-70 237.9 0.2 8.3e-55 186.6 0.1 2.0 1 1 0 2 2 2 2 Serpin (serine protease inhibitor) FAM35_C PF15793.5 PVD37313.1 - 0.019 14.3 0.1 8.1 5.8 0.1 2.5 2 1 0 2 2 2 0 Protein family FAM35, C-terminal Arm-DNA-bind_2 PF12167.8 PVD37313.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain ArfGap PF01412.18 PVD37314.1 - 1.9e-40 137.6 1.8 5.5e-40 136.1 0.0 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf NAC PF01849.18 PVD37314.1 - 7.5e-24 83.5 1.2 1.4e-23 82.6 0.2 2.0 2 0 0 2 2 2 1 NAC domain Ras PF00071.22 PVD37314.1 - 1.5e-17 63.7 0.0 2.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Ras family PH PF00169.29 PVD37314.1 - 4.9e-11 43.1 1.3 6e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 PVD37314.1 - 8.3e-08 32.7 0.1 2.4e-07 31.3 0.0 1.8 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37314.1 - 1.7e-05 25.3 0.9 0.0055 17.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD37314.1 - 8.4e-05 22.9 0.1 0.0044 17.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.6 PVD37314.1 - 0.0011 19.4 3.4 0.68 10.4 0.1 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain Roc PF08477.13 PVD37314.1 - 0.0022 18.2 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PH_8 PF15409.6 PVD37314.1 - 0.0092 16.2 0.7 2.6 8.4 0.1 3.0 3 0 0 3 3 2 1 Pleckstrin homology domain PH_6 PF15406.6 PVD37314.1 - 0.0093 16.2 2.5 0.016 15.5 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 PVD37314.1 - 0.02 15.4 1.6 0.1 13.2 0.0 3.0 4 0 0 4 4 3 0 Ankyrin repeat Arf PF00025.21 PVD37314.1 - 0.033 13.6 0.0 0.099 12.1 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family Ank_5 PF13857.6 PVD37314.1 - 0.23 11.8 1.5 0.28 11.6 0.3 1.8 2 0 0 2 2 1 0 Ankyrin repeats (many copies) HH_signal PF01085.18 PVD37316.1 - 9.7e-31 106.6 0.0 1.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain PMG PF05287.12 PVD37316.1 - 0.049 13.7 9.3 0.066 13.2 9.3 1.3 1 0 0 1 1 1 0 PMG protein DUF3060 PF11259.8 PVD37317.1 - 0.067 12.9 2.8 3.4 7.4 0.1 3.6 1 1 3 5 5 5 0 Protein of unknown function (DUF3060) Mitoc_mL59 PF18126.1 PVD37317.1 - 5.8 7.2 7.4 3.9e+02 1.3 7.4 2.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 HH_signal PF01085.18 PVD37318.1 - 6.6e-42 142.9 0.6 7.3e-42 142.8 0.6 1.0 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.11 PVD37318.1 - 7.9e-06 25.9 0.1 9e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase M15 Hint PF01079.20 PVD37319.1 - 6.1e-38 130.5 0.0 3.8e-37 127.9 0.0 2.2 1 1 1 2 2 2 1 Hint module DUF1736 PF08409.11 PVD37320.1 - 4.5e-07 29.8 5.5 9.9 6.2 0.0 6.2 2 1 8 10 10 10 8 Domain of unknown function (DUF1736) DUF21 PF01595.20 PVD37320.1 - 0.28 10.9 3.5 5.7 6.6 0.9 2.4 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Herpes_BLLF1 PF05109.13 PVD37320.1 - 0.34 8.8 26.2 2.6 5.9 26.2 1.9 1 1 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Ldh_1_N PF00056.23 PVD37321.1 - 3.2e-10 40.2 0.1 8.8e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain RL PF17797.1 PVD37321.1 - 1.8e-07 31.0 0.1 4.7e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 RL domain PAP_assoc PF03828.19 PVD37321.1 - 6e-06 26.4 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Ldh_1_C PF02866.18 PVD37321.1 - 8.9e-06 25.7 0.3 0.00014 21.9 0.0 2.7 3 0 0 3 3 3 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DOG1 PF14144.6 PVD37321.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Seed dormancy control TetR_C_8 PF14278.6 PVD37321.1 - 0.073 13.2 0.1 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region NTP_transf_2 PF01909.23 PVD37321.1 - 0.16 12.3 0.0 0.58 10.5 0.0 2.0 1 0 0 1 1 1 0 Nucleotidyltransferase domain FAST_2 PF08368.12 PVD37322.1 - 1.1e-08 35.7 0.0 4.5e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 PVD37322.1 - 4e-08 33.1 3.9 6.5e-06 26.0 0.7 2.9 2 1 0 2 2 2 2 FAST kinase-like protein, subdomain 1 polyprenyl_synt PF00348.17 PVD37323.1 - 1.8e-69 233.7 0.9 2.4e-69 233.3 0.9 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 PVD37323.1 - 0.00033 20.3 0.2 0.00053 19.7 0.2 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 BID PF06393.11 PVD37323.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) Ser_hydrolase PF06821.13 PVD37324.1 - 1.8e-11 44.2 0.0 2.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 PVD37324.1 - 3e-07 30.3 0.4 0.00051 19.8 0.0 2.4 1 1 1 3 3 3 2 alpha/beta hydrolase fold DUF1057 PF06342.12 PVD37324.1 - 7.2e-05 22.0 0.0 0.00028 20.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 PVD37324.1 - 0.00018 22.2 0.0 0.0048 17.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD37324.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 EPL1 PF10513.9 PVD37325.1 - 2e-14 54.3 2.6 2e-14 54.3 2.6 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like E_Pc_C PF06752.12 PVD37325.1 - 2.8e-13 50.5 25.1 2.8e-13 50.5 25.1 2.8 1 1 1 2 2 2 1 Enhancer of Polycomb C-terminus zf-C3Hc3H PF13891.6 PVD37326.1 - 2.3e-27 95.1 20.8 2e-15 56.9 4.1 2.6 2 0 0 2 2 2 2 Potential DNA-binding domain TPR_20 PF14561.6 PVD37326.1 - 0.048 14.0 1.7 2.4 8.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-primase PF09329.11 PVD37326.1 - 0.53 10.1 9.6 1.3 8.8 0.1 3.7 3 0 0 3 3 3 0 Primase zinc finger Gp-FAR-1 PF05823.12 PVD37326.1 - 0.56 10.5 4.8 0.9 9.9 0.1 2.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-TRM13_CCCH PF11722.8 PVD37326.1 - 9.7 6.1 9.5 51 3.8 2.9 3.4 2 1 0 2 2 2 0 CCCH zinc finger in TRM13 protein Fis1_TPR_C PF14853.6 PVD37327.1 - 0.0092 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat PEX11 PF05648.14 PVD37329.1 - 1.7e-48 165.0 3.8 2.1e-48 164.7 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FAD_binding_1 PF00667.20 PVD37330.1 - 6.2e-40 137.1 0.0 9.5e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PVD37330.1 - 2.6e-14 53.6 0.1 2.2e-06 27.9 0.0 2.9 1 1 1 2 2 2 2 Flavodoxin NAD_binding_1 PF00175.21 PVD37330.1 - 1.4e-09 38.6 0.1 7.5e-09 36.2 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 PVD37330.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain LMBR1 PF04791.16 PVD37331.1 - 3.9e-33 115.2 2.4 4.7e-33 114.9 2.4 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Pkinase_Tyr PF07714.17 PVD37332.1 - 1.8e-18 66.8 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37332.1 - 1.8e-17 63.6 0.0 2.7e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Activin_recp PF01064.23 PVD37332.1 - 3e-06 28.2 9.2 7.5e-06 27.0 9.2 1.7 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.23 PVD37332.1 - 0.034 14.1 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mid2 PF04478.12 PVD37332.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Pkinase_fungal PF17667.1 PVD37332.1 - 0.14 10.9 0.0 0.41 9.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SPAN PF02510.14 PVD37332.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein UPAR_LY6_2 PF16975.5 PVD37332.1 - 0.21 11.8 6.7 0.44 10.8 6.7 1.4 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 RIO1 PF01163.22 PVD37332.1 - 0.21 11.1 0.1 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Lactamase_B_2 PF12706.7 PVD37333.1 - 6.4e-12 45.4 0.0 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD37333.1 - 1.9e-09 37.8 0.0 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 PVD37333.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Pro_isomerase PF00160.21 PVD37334.1 - 2.4e-47 161.2 0.3 2.4e-47 161.2 0.3 2.5 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 PVD37334.1 - 8.3e-06 25.6 30.7 8.3e-06 25.6 30.7 10.8 4 2 7 11 11 11 2 Nuclear RNA-splicing-associated protein DUF908 PF06012.12 PVD37334.1 - 0.0014 18.1 6.9 0.0014 18.1 6.9 8.6 3 2 1 5 5 5 1 Domain of Unknown Function (DUF908) TFIIF_alpha PF05793.12 PVD37334.1 - 0.0024 16.5 20.6 0.0024 16.5 20.6 6.7 4 2 2 6 6 6 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_4 PF13637.6 PVD37335.1 - 2e-14 53.7 1.6 7.1e-10 39.2 0.2 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37335.1 - 4.1e-12 45.2 0.0 0.00017 21.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PVD37335.1 - 1.7e-11 44.5 0.5 2.4e-10 40.8 0.6 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PVD37335.1 - 6e-10 39.1 0.9 0.0014 19.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat zf-MYND PF01753.18 PVD37335.1 - 2.2e-07 30.8 19.7 4e-07 30.0 19.7 1.4 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 PVD37335.1 - 1.8e-06 28.1 0.3 0.042 14.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) VF530 PF09905.9 PVD37335.1 - 0.13 12.5 0.0 26 5.1 0.0 2.8 3 0 0 3 3 3 0 DNA-binding protein VF530 TraV PF09676.10 PVD37335.1 - 0.15 13.1 5.4 0.32 12.0 5.4 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) PTPlike_phytase PF14566.6 PVD37335.1 - 1.5 9.0 5.9 3 7.9 5.9 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PolC_DP2 PF03833.13 PVD37335.1 - 2.6 5.8 9.6 4 5.2 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pkinase PF00069.25 PVD37336.1 - 1.9e-74 250.4 0.0 2.1e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD37336.1 - 2.4e-35 122.1 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD37336.1 - 0.00022 20.3 0.1 0.011 14.7 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 PVD37336.1 - 0.003 16.9 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PVD37336.1 - 0.0047 16.9 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PVD37336.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PVD37336.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_3_Rpc31 PF11705.8 PVD37337.1 - 0.013 15.7 12.2 0.017 15.4 12.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4820 PF16091.5 PVD37337.1 - 0.08 12.3 3.7 0.1 11.9 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TLP-20 PF06088.11 PVD37337.1 - 0.15 11.9 1.0 0.19 11.6 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 PVD37337.1 - 0.22 10.2 2.5 0.24 10.1 2.5 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 PVD37337.1 - 0.24 10.7 14.1 0.16 11.3 11.6 1.7 2 0 0 2 2 2 0 NOA36 protein Prothymosin PF03247.14 PVD37337.1 - 0.33 11.4 28.2 0.46 11.0 28.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF913 PF06025.12 PVD37337.1 - 0.56 9.1 2.2 0.67 8.9 2.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 PVD37337.1 - 1.9 8.2 14.2 3.5 7.3 14.2 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 PVD37337.1 - 2.2 8.0 13.7 5 6.9 13.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 PVD37337.1 - 3.8 5.6 17.8 4.9 5.3 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 PVD37337.1 - 4.7 6.6 17.1 6.4 6.1 17.1 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 PVD37337.1 - 6.4 6.7 13.2 8.7 6.2 13.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 PVD37337.1 - 7.9 5.8 19.8 9.8 5.5 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2345 PF10106.9 PVD37338.1 - 0.00016 21.5 1.7 0.00021 21.2 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) OMS28_porin PF03532.13 PVD37338.1 - 1.5 8.0 6.7 1.8 7.7 6.7 1.0 1 0 0 1 1 1 0 OMS28 porin WD40 PF00400.32 PVD37339.1 - 1.1e-40 136.9 14.0 3.8e-10 40.2 0.3 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat U-box PF04564.15 PVD37339.1 - 1e-24 86.5 0.1 2.1e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.30 PVD37339.1 - 9.1e-18 64.5 0.0 2.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD37339.1 - 1.8e-14 53.6 0.0 3.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 PVD37339.1 - 4.7e-10 39.6 0.0 0.028 14.7 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD37339.1 - 3.7e-05 22.9 0.1 0.24 10.3 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SAM_3 PF18016.1 PVD37339.1 - 0.0002 21.1 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Frtz PF11768.8 PVD37339.1 - 0.00034 19.1 0.0 0.4 8.9 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz SAM_Ste50p PF09235.10 PVD37339.1 - 0.001 19.2 0.1 0.0032 17.7 0.1 1.8 1 0 0 1 1 1 1 Ste50p, sterile alpha motif zf-Nse PF11789.8 PVD37339.1 - 0.0022 17.8 0.0 0.0067 16.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PVD37339.1 - 0.0061 16.7 0.1 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein IGFBP PF00219.18 PVD37339.1 - 0.0063 17.1 11.1 0.017 15.8 11.1 1.7 1 0 0 1 1 1 1 Insulin-like growth factor binding protein Nup160 PF11715.8 PVD37339.1 - 0.033 12.8 0.2 12 4.4 0.0 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 SAM_PNT PF02198.16 PVD37339.1 - 0.039 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40_like PF17005.5 PVD37339.1 - 0.055 12.8 0.0 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain DUF2415 PF10313.9 PVD37339.1 - 0.32 11.0 3.5 2.4 8.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Zip PF02535.22 PVD37340.1 - 1.5e-51 175.6 20.2 6.6e-43 147.2 3.3 2.7 2 1 1 3 3 3 2 ZIP Zinc transporter SNURF PF07192.11 PVD37340.1 - 0.21 11.5 1.0 0.4 10.5 1.0 1.4 1 0 0 1 1 1 0 SNURF/RPN4 protein Romo1 PF10247.9 PVD37340.1 - 0.22 11.9 0.2 0.22 11.9 0.2 2.4 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 ZIP4_domain PF18292.1 PVD37342.1 - 7.6e-05 22.7 0.4 0.0014 18.5 0.1 2.3 2 0 0 2 2 2 1 Zinc transporter ZIP4 domain Lectin_C PF00059.21 PVD37343.1 - 5.3e-57 191.2 10.4 5.5e-17 62.5 0.1 5.3 5 0 0 5 5 5 4 Lectin C-type domain Amnionless PF14828.6 PVD37343.1 - 0.00046 19.1 0.0 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 Amnionless UL45 PF05473.12 PVD37343.1 - 0.00089 18.9 14.5 0.16 11.5 0.0 5.2 4 2 1 5 5 5 3 UL45 protein, carbohydrate-binding C-type lectin-like DUF3042 PF11240.8 PVD37343.1 - 0.045 13.8 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Keratin_2_tail PF16210.5 PVD37343.1 - 0.75 10.1 5.9 0.065 13.5 0.7 1.8 2 0 0 2 2 2 0 Keratin type II cytoskeletal 1 tail Lectin_C PF00059.21 PVD37344.1 - 3.1e-37 127.6 15.5 7.3e-18 65.3 0.3 3.7 4 1 0 4 4 4 3 Lectin C-type domain UL45 PF05473.12 PVD37344.1 - 0.00034 20.3 0.0 0.34 10.5 0.0 2.7 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 PVD37345.1 - 0.013 16.2 0.0 0.017 15.8 0.0 1.4 1 0 0 1 1 1 0 Lectin C-type domain UL45 PF05473.12 PVD37345.1 - 0.082 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Glyco_transf_36 PF06165.11 PVD37345.1 - 0.12 11.8 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 36 Thyroglobulin_1 PF00086.18 PVD37347.1 - 4.3e-15 55.1 5.5 8.7e-11 41.3 2.7 2.7 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.18 PVD37348.1 - 1.1e-13 50.7 9.5 2.1e-10 40.1 2.8 2.8 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat UPF0552 PF10574.9 PVD37348.1 - 0.71 9.2 6.2 6.4 6.1 1.6 2.4 1 1 2 3 3 3 0 Arp2/3-interacting proteins Arpin Pentapeptide_2 PF01469.18 PVD37348.1 - 4.9 7.1 43.0 0.053 13.4 15.8 3.4 2 1 0 3 3 3 0 Pentapeptide repeats (8 copies) Nodulin_late PF07127.11 PVD37350.1 - 0.1 13.0 0.5 0.1 13.0 0.5 2.4 3 0 0 3 3 3 0 Late nodulin protein DUF4713 PF15831.5 PVD37350.1 - 0.1 13.1 0.9 0.33 11.4 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Crystall_3 PF08964.10 PVD37351.1 - 0.34 11.1 3.8 1.3 9.2 0.3 2.8 1 1 2 3 3 3 0 Beta/Gamma crystallin DUF4837 PF16125.5 PVD37351.1 - 1.5 7.8 8.6 0.31 10.0 1.9 2.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4837) T3RM_EcoP15I_C PF18273.1 PVD37351.1 - 2.5 8.5 9.7 19 5.7 6.0 3.1 2 1 1 3 3 3 0 Type III R-M EcoP15I C-terminal domain HSF_DNA-bind PF00447.17 PVD37351.1 - 5.7 7.6 14.5 8.8 7.0 0.4 3.8 1 1 2 3 3 3 0 HSF-type DNA-binding DUF2063 PF09836.9 PVD37351.1 - 5.8 7.2 13.3 3.4e+03 -1.6 12.2 4.2 1 1 0 1 1 1 0 Putative DNA-binding domain 7tm_1 PF00001.21 PVD37352.1 - 8.3e-20 71.2 19.2 1.2e-19 70.7 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 PVD37352.1 - 0.62 10.0 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family CBM_14 PF01607.24 PVD37354.1 - 2.4e-10 40.4 2.9 5.3e-10 39.3 2.8 1.7 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain PhetRS_B1 PF18262.1 PVD37355.1 - 7.3e-23 80.6 0.7 9.4e-23 80.3 0.7 1.2 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain tRNA_synthFbeta PF17759.1 PVD37356.1 - 6.7e-54 182.6 0.0 7.6e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 PVD37356.1 - 0.062 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain AA_permease_2 PF13520.6 PVD37357.1 - 8.4e-50 169.8 33.6 8.4e-50 169.8 33.6 2.2 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 PVD37357.1 - 1.8e-38 132.4 28.5 1.8e-38 132.4 28.5 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 PVD37357.1 - 4.4e-24 84.3 5.7 4.4e-24 84.3 5.7 3.5 4 0 0 4 4 4 1 C-terminus of AA_permease Trep_Strep PF09605.10 PVD37357.1 - 0.0058 16.6 4.3 0.0058 16.6 4.3 4.9 5 1 0 5 5 5 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Phage_int_SAM_2 PF12834.7 PVD37358.1 - 0.011 16.4 0.1 0.33 11.7 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal EF-hand_7 PF13499.6 PVD37359.1 - 3.6e-17 62.6 14.2 3.4e-07 30.6 0.3 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 PVD37359.1 - 8.2e-16 56.3 16.6 0.0034 16.8 0.0 8.0 8 0 0 8 8 8 5 EF hand EF-hand_6 PF13405.6 PVD37359.1 - 1.1e-13 49.9 9.7 0.045 13.7 0.0 7.0 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.6 PVD37359.1 - 3.9e-12 45.8 14.6 0.00084 19.1 0.0 6.3 6 1 0 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 PVD37359.1 - 5.3e-11 41.5 15.1 0.0039 16.6 0.0 7.9 9 0 0 9 9 9 3 EF hand SPARC_Ca_bdg PF10591.9 PVD37359.1 - 0.018 15.3 14.2 0.36 11.2 0.1 3.6 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region SHOCT PF09851.9 PVD37359.1 - 1.9 8.3 4.2 3.6 7.4 0.1 3.2 3 0 0 3 3 3 0 Short C-terminal domain AMP-binding PF00501.28 PVD37365.1 - 1.6e-102 343.2 0.0 3.3e-102 342.2 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD37365.1 - 3.6e-05 24.6 0.4 0.00016 22.6 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HSNSD PF12062.8 PVD37366.1 - 4.6e-179 596.2 0.1 6.4e-179 595.8 0.1 1.1 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 PVD37366.1 - 9.9e-38 130.1 0.4 1.6e-37 129.4 0.4 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD37366.1 - 3.1e-10 40.8 2.2 6.3e-05 23.5 0.4 2.6 1 1 1 2 2 2 2 Sulfotransferase family Folliculin PF11704.8 PVD37367.1 - 2.2e-52 177.6 0.0 3.4e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 PVD37367.1 - 6.8e-34 117.5 0.1 1.2e-33 116.8 0.1 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain MACPF PF01823.19 PVD37369.1 - 8.5e-21 75.0 0.0 1.4e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain PAN_3 PF08277.12 PVD37369.1 - 1.2e-06 28.3 12.4 0.0032 17.2 1.5 3.0 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.26 PVD37369.1 - 5.7e-06 26.2 15.0 0.00051 19.9 3.9 2.4 1 1 1 2 2 2 2 PAN domain PAN_2 PF08276.11 PVD37369.1 - 9.3e-05 22.5 1.5 9.3e-05 22.5 1.5 3.4 2 2 2 4 4 4 1 PAN-like domain PAN_4 PF14295.6 PVD37369.1 - 0.00033 20.5 8.2 0.12 12.3 0.4 2.8 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 PVD37369.1 - 0.073 13.3 8.9 1.8 8.9 1.9 2.4 2 0 0 2 2 2 0 MANEC domain LRR_8 PF13855.6 PVD37370.1 - 1.3e-18 66.5 12.9 3.1e-10 39.7 2.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD37370.1 - 5.5e-12 45.7 14.8 7e-07 29.5 2.3 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD37370.1 - 7.8e-05 22.2 0.6 0.0001 21.9 0.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 PVD37370.1 - 0.0019 18.5 5.3 0.65 10.8 0.6 4.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD37370.1 - 0.0021 18.0 1.5 0.53 10.5 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeat Tubulin PF00091.25 PVD37371.1 - 5.3e-34 118.1 0.0 8e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PVD37371.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin C-terminal domain Tubulin_2 PF13809.6 PVD37371.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 PVD37371.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Chitin_synth_2 PF03142.15 PVD37373.1 - 4.1e-29 101.6 1.3 1.5e-24 86.6 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD37373.1 - 2.1e-13 50.6 0.7 5.5e-13 49.3 0.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD37373.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_11 PF01531.16 PVD37375.1 - 3.9e-33 114.9 0.3 5e-33 114.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 PVD37375.1 - 2.9e-05 23.9 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FA_desaturase PF00487.24 PVD37376.1 - 1.5e-39 136.4 21.3 1.5e-39 136.4 21.3 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Ank_2 PF12796.7 PVD37377.1 - 3.1e-25 88.6 0.0 3.5e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD37377.1 - 1.1e-16 60.7 0.0 1.5e-07 31.6 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD37377.1 - 1.4e-14 54.3 0.2 2.3e-05 24.8 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37377.1 - 2.8e-11 42.6 0.0 0.0081 16.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PVD37377.1 - 2.7e-09 37.1 0.0 0.0018 18.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat DUF3944 PF13099.6 PVD37377.1 - 0.022 14.6 0.5 0.062 13.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Hormone_recep PF00104.30 PVD37379.1 - 6.6e-08 32.4 0.2 7.5e-08 32.2 0.2 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD37380.1 - 2.7e-29 101.4 14.9 6.2e-29 100.3 14.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FAM131 PF15010.6 PVD37380.1 - 0.0068 16.4 0.7 0.0068 16.4 0.7 2.2 1 1 1 2 2 2 1 Putative cell signalling PglZ PF08665.12 PVD37380.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Arylesterase PF01731.20 PVD37381.1 - 9e-19 67.5 0.2 2e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 PVD37381.1 - 1.6e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 PVD37381.1 - 3.1e-05 24.0 0.1 0.00055 20.0 0.1 2.3 2 0 0 2 2 2 1 Strictosidine synthase Lactonase PF10282.9 PVD37381.1 - 0.028 13.7 0.1 0.097 11.9 0.0 1.8 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 PVD37382.1 - 2e-41 140.1 2.6 1.1e-19 70.4 0.1 2.9 2 0 0 2 2 2 2 Arylesterase SGL PF08450.12 PVD37382.1 - 3.8e-22 79.1 0.1 2.3e-10 40.5 0.0 2.8 2 2 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 PVD37382.1 - 4.6e-10 39.5 0.2 0.00064 19.8 0.1 4.2 4 0 0 4 4 4 2 Strictosidine synthase Lactonase PF10282.9 PVD37382.1 - 1.7e-06 27.5 0.0 0.027 13.7 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller DHOase PF12890.7 PVD37382.1 - 0.029 14.3 0.0 0.73 9.8 0.0 2.6 1 1 0 1 1 1 0 Dihydro-orotase-like Paralemmin PF03285.15 PVD37382.1 - 0.06 12.9 0.1 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Paralemmin Ribosomal_S26e PF01283.19 PVD37383.1 - 9.2e-53 177.2 7.7 1.2e-52 176.9 7.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Cdc6_C PF09079.11 PVD37384.1 - 1.4e-16 60.2 1.1 2.8e-16 59.2 1.1 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 PVD37384.1 - 1.3e-07 31.6 0.9 1.3e-07 31.6 0.9 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 PVD37384.1 - 6.2e-05 23.4 0.0 0.00021 21.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AF-4 PF05110.13 PVD37385.1 - 2.3 6.2 41.5 2.8 5.9 41.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MA3 PF02847.17 PVD37386.1 - 3e-13 49.7 2.1 3.8e-13 49.4 0.6 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 PVD37386.1 - 2e-12 47.2 4.0 2e-12 47.2 4.0 3.1 2 2 1 3 3 3 1 MIF4G domain Tricho_coat PF05892.11 PVD37386.1 - 0.069 12.9 0.3 7.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Trichovirus coat protein Nop14 PF04147.12 PVD37386.1 - 0.09 11.0 18.7 0.13 10.5 4.8 2.3 2 0 0 2 2 2 0 Nop14-like family RP-C_C PF11800.8 PVD37386.1 - 0.12 12.5 6.3 2.9 7.9 1.7 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region DNA_pol_phi PF04931.13 PVD37386.1 - 0.9 7.6 22.6 0.43 8.6 5.8 2.4 2 0 0 2 2 2 0 DNA polymerase phi DDHD PF02862.17 PVD37386.1 - 1.4 9.0 11.6 7.2 6.7 7.8 2.9 2 1 0 2 2 2 0 DDHD domain FAM176 PF14851.6 PVD37386.1 - 1.6 8.4 12.2 2.1 8.0 0.9 2.7 2 0 0 2 2 2 0 FAM176 family SpoIIIAH PF12685.7 PVD37386.1 - 4.4 7.1 17.3 1.4 8.7 0.5 2.7 3 0 0 3 3 3 0 SpoIIIAH-like protein Apt1 PF10351.9 PVD37386.1 - 8.7 5.1 13.6 2.8 6.7 8.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain CSRNP_N PF16019.5 PVD37386.1 - 8.8 6.2 8.8 3.9 7.3 1.6 2.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus 7tm_1 PF00001.21 PVD37387.1 - 1.5e-16 60.6 6.7 1.9e-16 60.2 6.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OST3_OST6 PF04756.13 PVD37387.1 - 0.15 11.4 3.4 0.2 10.9 3.4 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RPAP3_C PF13877.6 PVD37388.1 - 0.013 16.0 0.2 7.6 7.1 0.1 3.1 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 PaO PF08417.12 PVD37388.1 - 0.014 15.6 0.4 0.088 13.0 0.0 2.5 2 0 0 2 2 2 0 Pheophorbide a oxygenase GxGYxYP_C PF14323.6 PVD37388.1 - 0.019 14.8 3.2 0.13 12.1 2.2 2.6 2 1 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain OSCP PF00213.18 PVD37388.1 - 0.055 13.6 7.9 3.2 7.8 0.0 3.3 2 2 1 3 3 3 0 ATP synthase delta (OSCP) subunit Ig_5 PF16681.5 PVD37388.1 - 0.09 13.2 1.9 11 6.5 0.1 2.8 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain GAS PF13851.6 PVD37388.1 - 0.38 10.1 28.4 0.13 11.6 24.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prp18 PF02840.15 PVD37388.1 - 0.89 9.6 7.4 0.93 9.5 4.3 2.7 2 1 0 2 2 2 0 Prp18 domain ARL2_Bind_BART PF11527.8 PVD37388.1 - 2.4 8.3 6.8 0.56 10.3 0.1 3.0 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART FAIM1 PF06905.13 PVD37389.1 - 3.6e-80 267.8 2.5 4.1e-80 267.6 2.5 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) TPR_2 PF07719.17 PVD37390.1 - 1.8e-15 55.8 12.6 0.02 15.0 0.1 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 PVD37390.1 - 1.4e-12 46.8 11.7 0.006 16.3 0.6 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PVD37390.1 - 2.3e-11 43.8 16.9 1.1e-05 25.6 2.8 5.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 PVD37390.1 - 8e-09 35.1 4.7 0.00056 19.5 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 PVD37390.1 - 1.4e-08 34.2 6.6 0.17 12.0 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PVD37390.1 - 3.4e-08 33.1 7.8 0.084 13.1 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD37390.1 - 9.1e-08 32.3 2.6 0.024 15.4 0.0 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD37390.1 - 7.5e-06 25.5 6.1 0.00015 21.3 4.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 PVD37390.1 - 3.7e-05 23.9 5.3 2 8.7 0.7 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PVD37390.1 - 7.7e-05 23.1 3.9 28 5.7 0.0 5.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PVD37390.1 - 0.00013 21.7 10.4 2.9 7.9 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 PVD37390.1 - 0.00021 21.6 0.2 1.7 9.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD37390.1 - 0.00048 20.7 10.7 3.3 8.4 0.3 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD37390.1 - 0.0035 17.8 4.9 8.4 7.0 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 PVD37390.1 - 0.0051 16.9 3.3 0.45 10.6 0.1 3.8 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) Paf67 PF10255.9 PVD37390.1 - 0.0096 15.0 0.2 3.2 6.7 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 Phage_GPL PF05926.11 PVD37390.1 - 0.072 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Phage head completion protein (GPL) Pex14_N PF04695.13 PVD37390.1 - 0.21 12.2 9.1 0.38 11.4 9.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 PVD37392.1 - 5.3e-69 233.0 12.2 5.3e-69 233.0 12.2 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter PrgI PF12666.7 PVD37392.1 - 2.8 8.7 7.4 21 5.9 0.0 3.3 3 0 0 3 3 3 0 PrgI family protein Pkinase_Tyr PF07714.17 PVD37393.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37393.1 - 0.0017 17.8 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CP2 PF04516.15 PVD37394.1 - 6.1e-65 218.7 0.0 1e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor 2-Hacid_dh_C PF02826.19 PVD37395.1 - 2.3e-34 118.3 0.1 6.6e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PVD37395.1 - 3.3e-28 98.0 0.0 4.2e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 PVD37395.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MurB_C PF02873.16 PVD37395.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF5319 PF17252.2 PVD37396.1 - 0.016 15.4 0.0 0.021 15.0 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5319) Glyco_hydro_72 PF03198.14 PVD37396.1 - 0.12 11.6 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Glucanosyltransferase GST_C_6 PF17171.4 PVD37398.1 - 6.1e-23 80.4 0.1 1.2e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PVD37398.1 - 1.5e-21 77.0 0.0 6.4e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PVD37398.1 - 6.2e-16 58.9 0.0 1.5e-15 57.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 PVD37398.1 - 1.3e-06 28.3 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD37398.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD37398.1 - 0.0075 16.4 0.0 0.021 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BTB PF00651.31 PVD37400.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Sulfotransfer_3 PF13469.6 PVD37404.1 - 9.2e-08 32.7 0.0 1.4e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD37404.1 - 0.00021 20.8 0.2 0.00058 19.4 0.2 1.8 1 1 0 1 1 1 1 Sulfotransferase domain T4bSS_IcmS PF12608.8 PVD37404.1 - 0.003 17.9 0.7 13 6.2 0.0 3.7 1 1 3 4 4 4 3 Type IVb secretion, IcmS, effector-recruitment Sulfotransfer_1 PF00685.27 PVD37405.1 - 1.8e-15 57.2 0.0 3.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD37405.1 - 1.2e-11 45.5 0.1 1.3e-08 35.5 0.1 3.0 1 1 0 1 1 1 1 Sulfotransferase family Ank_2 PF12796.7 PVD37406.1 - 7.2e-08 32.9 0.0 0.026 15.1 0.0 4.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Zfx_Zfy_act PF04704.13 PVD37406.1 - 0.15 11.2 6.3 1.3 8.1 1.4 2.1 1 1 1 2 2 2 0 Zfx / Zfy transcription activation region T2SS-T3SS_pil_N PF13629.6 PVD37406.1 - 0.35 10.6 0.2 0.35 10.6 0.2 3.2 1 1 3 4 4 4 0 Pilus formation protein N terminal region Flavi_NS2B PF01002.19 PVD37406.1 - 4.7 7.1 18.6 21 5.0 2.5 3.8 1 1 4 5 5 5 0 Flavivirus non-structural protein NS2B Sulfotransfer_3 PF13469.6 PVD37407.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD37408.1 - 1e-15 57.9 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD37408.1 - 5.6e-12 46.5 0.1 5.9e-09 36.6 0.1 3.0 1 1 0 1 1 1 1 Sulfotransferase family ANF_receptor PF01094.28 PVD37409.1 - 8.3e-37 127.1 0.0 9.9e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD37409.1 - 8.6e-08 32.2 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Pkinase_Tyr PF07714.17 PVD37410.1 - 1.6e-24 86.6 0.1 2.1e-15 56.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PVD37410.1 - 2e-20 73.3 0.0 3.5e-20 72.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain VHS PF00790.19 PVD37411.1 - 3.7e-39 133.8 0.1 1.7e-38 131.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 PVD37411.1 - 1.3e-23 83.1 10.5 2.5e-23 82.2 3.7 3.3 3 0 0 3 3 3 1 GAT domain ENTH PF01417.20 PVD37411.1 - 0.039 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Ribosomal_60s PF00428.19 PVD37411.1 - 1.8 9.2 7.8 3.1 8.5 2.4 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein LRR_9 PF14580.6 PVD37412.1 - 5.7e-17 61.8 5.7 6.7e-16 58.3 1.4 3.2 1 1 2 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 PVD37412.1 - 4.9e-13 49.0 15.6 8.6e-05 22.8 2.1 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD37412.1 - 1.5e-09 37.4 13.0 1.5e-06 27.9 5.0 3.1 2 0 0 2 2 2 2 Leucine rich repeat UPF0061 PF02696.14 PVD37412.1 - 0.014 14.2 6.4 0.027 13.3 6.4 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family LRR_1 PF00560.33 PVD37412.1 - 1.4 9.8 10.1 7.2 7.6 0.1 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Rrn6 PF10214.9 PVD37412.1 - 2 6.8 7.1 2.5 6.5 7.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LRR_6 PF13516.6 PVD37412.1 - 4.7 7.5 5.7 63 4.0 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat ATP12 PF07542.11 PVD37413.1 - 4.9e-37 126.9 0.4 6.4e-37 126.5 0.4 1.1 1 0 0 1 1 1 1 ATP12 chaperone protein HEPN PF05168.14 PVD37413.1 - 0.13 12.4 0.1 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 HEPN domain Vac_ImportDeg PF09783.9 PVD37414.1 - 9.3e-54 181.6 4.3 1.1e-53 181.3 4.3 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pkinase PF00069.25 PVD37415.1 - 4.2e-14 52.5 0.2 2.1e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I PF08311.12 PVD37415.1 - 1.5e-10 41.1 0.0 3.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.17 PVD37415.1 - 4.8e-06 26.0 0.0 9.6e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 PVD37415.1 - 0.0034 17.5 0.5 0.59 10.3 0.0 3.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Kinase-like PF14531.6 PVD37415.1 - 0.02 14.2 1.0 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Mad3_BUB1_I_2 PF17014.5 PVD37415.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Pox_ser-thr_kin PF05445.11 PVD37415.1 - 0.059 12.3 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CCDC66 PF15236.6 PVD37415.1 - 6 6.7 16.6 0.36 10.6 11.0 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 KH_1 PF00013.29 PVD37416.1 - 8.8e-34 115.2 8.1 1.4e-14 53.6 0.3 5.2 5 0 0 5 5 5 4 KH domain SAM_1 PF00536.30 PVD37416.1 - 2.9e-13 50.0 0.1 6.6e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD37416.1 - 6.9e-10 38.9 0.1 2.8e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 PVD37416.1 - 8.4e-06 26.1 0.5 0.56 10.7 0.0 3.6 3 0 0 3 3 3 2 GLD-3 KH domain 5 KH_2 PF07650.17 PVD37416.1 - 0.00011 22.0 0.0 0.77 9.6 0.0 2.7 2 0 0 2 2 2 2 KH domain SLS PF14611.6 PVD37416.1 - 0.00012 21.9 0.0 0.11 12.4 0.0 3.5 3 1 1 4 4 4 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 PVD37416.1 - 0.12 12.2 0.4 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 KH domain Cadherin PF00028.17 PVD37418.1 - 7e-297 959.1 120.7 6.3e-15 55.4 0.3 33.5 34 0 0 34 34 34 32 Cadherin domain Cadherin_pro PF08758.11 PVD37418.1 - 1.3e-10 41.3 0.4 0.37 11.0 0.0 9.6 10 0 0 10 10 10 2 Cadherin prodomain like RET_CLD1 PF17756.1 PVD37418.1 - 1.7e-10 41.3 0.0 0.4 11.0 0.0 10.4 13 0 0 13 13 13 2 RET Cadherin like domain 1 Y_Y_Y PF07495.13 PVD37418.1 - 4.6e-06 26.5 6.3 68 3.5 0.0 12.0 13 0 0 13 13 13 0 Y_Y_Y domain DUF5643 PF18705.1 PVD37418.1 - 0.041 13.9 2.3 13 5.8 0.2 4.2 2 1 1 3 3 3 0 Family of unknown function (DUF5643) PGM1_C PF18105.1 PVD37418.1 - 0.16 11.5 5.3 23 4.6 0.0 4.5 5 0 0 5 5 5 0 PGM1 C-terminal domain DUF2460 PF09343.10 PVD37418.1 - 0.79 9.2 4.7 5.7 6.4 0.0 4.9 6 0 0 6 6 6 0 Conserved hypothetical protein 2217 (DUF2460) AltA1 PF16541.5 PVD37418.1 - 8.2 7.3 16.8 39 5.2 0.0 7.9 9 1 1 10 10 10 0 Alternaria alternata allergen 1 Cadherin PF00028.17 PVD37419.1 - 7.2e-186 603.3 69.4 2.4e-13 50.3 1.1 26.3 24 2 2 26 26 26 25 Cadherin domain RET_CLD1 PF17756.1 PVD37419.1 - 0.032 14.5 0.0 18 5.6 0.0 5.5 8 0 0 8 8 8 0 RET Cadherin like domain 1 Cadherin PF00028.17 PVD37420.1 - 2.4e-162 527.9 83.3 1.3e-16 60.8 0.1 23.0 21 2 1 22 22 22 21 Cadherin domain Cadherin_3 PF16184.5 PVD37420.1 - 0.003 17.5 23.3 1.8 8.6 0.6 8.6 9 0 0 9 9 9 3 Cadherin-like MpPF1 PF07668.11 PVD37420.1 - 0.0081 15.5 3.6 0.92 8.7 1.4 2.8 2 0 0 2 2 2 2 M penetrans paralogue family 1 B3_4 PF03483.17 PVD37420.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 B3/4 domain PRIMA1 PF16101.5 PVD37421.1 - 0.00081 19.4 10.5 0.0011 19.0 10.5 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 PVD37421.1 - 0.0076 16.4 1.6 0.0084 16.2 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator DEC-1_N PF04625.13 PVD37421.1 - 1 8.3 5.8 1.1 8.2 5.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Trypsin PF00089.26 PVD37423.1 - 1.1e-62 211.8 0.8 1.6e-62 211.2 0.8 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD37423.1 - 3.4e-05 24.2 0.0 6.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD37423.1 - 0.0008 20.3 0.0 0.0015 19.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 PVD37423.1 - 0.0045 16.6 0.0 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 WD40 PF00400.32 PVD37424.1 - 3e-57 189.3 19.7 3.4e-11 43.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 PVD37424.1 - 3.7e-38 130.7 4.5 7.5e-38 129.7 4.5 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 PVD37424.1 - 4.1e-16 59.1 0.0 0.00085 19.6 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD37424.1 - 4.1e-06 26.0 0.0 0.06 12.3 0.0 4.5 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PVD37424.1 - 4.4e-06 25.6 4.0 0.012 14.3 0.1 3.7 3 2 1 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 PVD37424.1 - 4.9e-05 22.8 0.0 0.085 12.2 0.0 4.3 4 1 0 5 5 5 1 WD40-like domain eIF2A PF08662.11 PVD37424.1 - 0.0027 17.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 PVD37424.1 - 0.0032 16.8 0.0 11 5.2 0.0 3.3 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 PVD37424.1 - 0.023 14.6 0.0 2.5 8.2 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat LisH PF08513.11 PVD37424.1 - 0.029 14.3 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 LisH Cytochrom_D1 PF02239.16 PVD37424.1 - 0.033 12.7 0.4 0.28 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain LisH_TPL PF17814.1 PVD37424.1 - 0.077 12.7 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain ASH PF15780.5 PVD37425.1 - 3.1e-29 101.0 14.9 9.5e-06 25.7 0.1 9.8 9 0 0 9 9 9 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 PVD37425.1 - 2.6e-15 56.2 12.1 1.7e-05 24.6 0.3 7.9 8 0 0 8 8 8 3 MSP (Major sperm protein) domain PapD-like PF14874.6 PVD37425.1 - 2.6e-09 37.1 0.4 0.41 10.8 0.0 6.6 7 0 0 7 7 7 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 PVD37425.1 - 3.5e-05 24.0 7.5 1.3 9.3 0.1 6.5 7 0 0 7 7 7 1 Transmembrane protein 131-like DUF1573 PF07610.11 PVD37425.1 - 0.00065 19.7 1.1 2.2 8.4 0.0 5.5 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) BsuPI PF12690.7 PVD37425.1 - 0.11 12.6 2.2 39 4.4 0.0 4.4 6 0 0 6 6 6 0 Intracellular proteinase inhibitor DUF5001 PF16392.5 PVD37425.1 - 0.71 9.8 5.9 8.2 6.4 0.0 3.6 4 0 0 4 4 4 0 Ig-like domain Gelsolin PF00626.22 PVD37426.1 - 3e-76 251.3 0.0 3.7e-16 58.8 0.0 6.5 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 PVD37426.1 - 1.4e-14 53.8 3.9 4.1e-14 52.3 3.9 1.9 1 0 0 1 1 1 1 Villin headpiece domain NIF PF03031.18 PVD37427.1 - 1.6e-53 180.7 0.0 2e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_12 PF13424.6 PVD37428.1 - 6e-56 186.7 26.0 7.7e-18 64.6 0.3 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 PVD37428.1 - 1.8e-46 154.8 20.6 1.9e-09 37.1 0.0 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 PVD37428.1 - 1.7e-28 97.2 19.0 1.8e-06 27.5 0.9 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 PVD37428.1 - 1.2e-25 87.6 12.0 0.00031 20.6 0.3 8.1 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD37428.1 - 1.3e-21 74.9 23.0 0.00071 19.6 0.5 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 PVD37428.1 - 5.2e-16 57.4 23.8 0.013 15.5 0.3 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD37428.1 - 7e-16 58.5 5.9 2.5e-09 37.0 0.4 2.9 1 1 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 PVD37428.1 - 3.9e-08 33.8 24.5 0.0007 20.2 0.3 6.3 5 2 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PVD37428.1 - 1e-07 32.1 14.9 0.6 11.1 0.1 6.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 PVD37428.1 - 3.8e-07 30.0 5.9 1.7 9.2 0.3 6.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD37428.1 - 9.8e-07 29.2 11.4 0.0011 19.5 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.12 PVD37428.1 - 6e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2225 PF09986.9 PVD37428.1 - 0.00014 21.7 1.0 0.53 10.0 0.1 3.3 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 PVD37428.1 - 0.00074 19.5 12.5 0.11 12.6 0.4 5.3 5 0 0 5 5 4 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 PVD37428.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 3.3 3 2 0 3 3 2 1 AAA ATPase domain TPR_3 PF07720.12 PVD37428.1 - 0.017 15.1 13.5 11 6.2 0.3 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PVD37428.1 - 0.026 15.1 12.1 5.5 7.8 0.2 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4062 PF13271.6 PVD37428.1 - 0.059 13.7 1.9 22 5.5 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) ANAPC3 PF12895.7 PVD37428.1 - 0.11 12.7 8.9 6 7.2 0.0 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4810 PF16068.5 PVD37428.1 - 0.26 11.9 5.4 0.52 10.9 0.1 3.9 3 1 1 4 4 3 0 Domain of unknown function (DUF4810) TPR_11 PF13414.6 PVD37428.1 - 0.27 11.0 20.5 16 5.3 0.0 6.1 6 0 0 6 6 6 0 TPR repeat GIT_CC PF16559.5 PVD37428.1 - 0.64 9.9 3.5 2.1 8.3 0.8 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 PVD37428.1 - 4 7.6 15.0 0.35 11.0 8.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF4051 PF13260.6 PVD37428.1 - 5.5 6.8 6.5 6.2 6.6 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4051) Macoilin PF09726.9 PVD37428.1 - 9.8 4.6 14.2 16 3.9 14.2 1.2 1 0 0 1 1 1 0 Macoilin family I-set PF07679.16 PVD37430.1 - 1.1e-61 204.9 0.0 5.1e-20 71.3 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD37430.1 - 1e-46 157.4 0.1 1.2e-16 61.0 0.1 4.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 PVD37430.1 - 1.9e-34 117.8 0.0 1.7e-11 44.3 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 PVD37430.1 - 4.1e-32 110.2 0.2 4.9e-12 45.9 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 PVD37430.1 - 1.7e-17 63.6 7.6 1.7e-05 24.9 0.0 7.0 4 3 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD37430.1 - 3.6e-05 23.8 1.0 1.4 9.1 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD37430.1 - 0.00049 20.5 0.0 3.1 8.2 0.0 3.4 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD37430.1 - 0.011 15.8 0.0 6.3 6.9 0.0 2.9 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF11 PF01345.18 PVD37430.1 - 0.013 15.8 0.8 0.013 15.8 0.8 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF11 Receptor_2B4 PF11465.8 PVD37430.1 - 0.019 15.2 0.1 7.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 I-set PF07679.16 PVD37431.1 - 1e-109 358.8 0.0 1.7e-20 72.9 0.0 8.6 7 1 1 8 8 8 5 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD37431.1 - 2.9e-71 236.0 0.0 1.6e-13 51.0 0.0 7.2 6 0 0 6 6 5 5 Immunoglobulin domain ig PF00047.25 PVD37431.1 - 6.2e-46 154.5 0.0 1.2e-08 34.9 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 PVD37431.1 - 2.3e-44 149.6 0.0 2.1e-07 31.2 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain RhoGEF PF00621.20 PVD37431.1 - 4e-25 89.1 0.0 6.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain fn3 PF00041.21 PVD37431.1 - 7.6e-21 74.3 0.5 3.5e-09 36.9 0.0 4.3 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 PVD37431.1 - 1.2e-17 64.0 0.1 0.0057 16.8 0.0 7.4 5 2 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD37431.1 - 4.7e-16 58.6 0.0 0.026 14.6 0.0 7.0 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 PVD37431.1 - 5.5e-10 38.7 0.0 0.55 9.8 0.0 5.1 4 0 0 4 4 4 4 Immunoglobulin domain Izumo-Ig PF16706.5 PVD37431.1 - 2.5e-06 27.4 0.0 0.029 14.4 0.0 4.3 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 PVD37431.1 - 0.0051 17.0 0.0 5.5 7.3 0.0 3.8 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain IQ_SEC7_PH PF16453.5 PVD37431.1 - 0.017 15.1 0.0 0.068 13.1 0.0 2.0 1 0 0 1 1 1 0 PH domain PH PF00169.29 PVD37431.1 - 0.049 14.2 0.0 0.25 11.9 0.0 2.4 1 0 0 1 1 1 0 PH domain Pur_ac_phosph_N PF16656.5 PVD37431.1 - 0.049 14.2 6.1 30 5.3 0.0 5.2 4 1 0 4 4 3 0 Purple acid Phosphatase, N-terminal domain DUF1053 PF06327.14 PVD37431.1 - 7.1 7.2 8.3 2 9.0 2.2 3.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) fn3 PF00041.21 PVD37432.1 - 5.9e-110 359.8 41.9 2.9e-09 37.1 0.2 14.4 13 1 0 13 13 13 13 Fibronectin type III domain Pkinase PF00069.25 PVD37432.1 - 6.5e-96 320.7 0.0 2.2e-61 207.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 PVD37432.1 - 1.5e-48 162.8 0.0 2.3e-16 59.6 0.0 5.4 5 0 0 5 5 4 3 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 PVD37432.1 - 3.8e-48 164.0 0.0 4.8e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ig_3 PF13927.6 PVD37432.1 - 3e-33 114.2 0.0 1.1e-10 41.9 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Tissue_fac PF01108.17 PVD37432.1 - 1.4e-23 82.7 0.5 0.022 14.6 0.0 10.7 11 0 0 11 11 11 6 Tissue factor Ig_2 PF13895.6 PVD37432.1 - 2.7e-22 78.9 0.0 9.4e-08 32.3 0.0 3.9 4 0 0 4 4 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 PVD37432.1 - 1.1e-21 77.2 24.7 0.15 12.7 0.0 13.6 14 0 0 14 14 12 7 Purple acid Phosphatase, N-terminal domain ig PF00047.25 PVD37432.1 - 2e-20 72.8 0.0 1.4e-06 28.4 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain PhoD_N PF16655.5 PVD37432.1 - 2.5e-11 44.0 12.6 5.6 7.6 0.0 12.8 13 1 0 13 13 13 1 PhoD-like phosphatase, N-terminal domain fn3_2 PF16893.5 PVD37432.1 - 3.5e-10 39.9 0.0 0.073 13.2 0.0 7.5 9 0 0 9 9 7 2 Fibronectin type III domain V-set PF07686.17 PVD37432.1 - 8.5e-08 32.4 0.1 0.0088 16.2 0.0 4.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD37432.1 - 1.3e-06 27.9 0.0 0.19 11.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain DUF2369 PF10179.9 PVD37432.1 - 7e-06 26.3 0.3 0.56 10.6 0.0 7.3 10 0 0 10 10 9 1 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 PVD37432.1 - 0.0025 17.9 0.1 0.061 13.4 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain DUF3146 PF11344.8 PVD37432.1 - 0.0079 15.8 0.3 11 5.7 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF3146) Kdo PF06293.14 PVD37432.1 - 0.011 15.2 0.5 0.12 11.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Izumo-Ig PF16706.5 PVD37432.1 - 0.095 12.8 0.0 25 5.0 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Trypsin PF00089.26 PVD37433.1 - 1.8e-55 188.2 0.1 2.1e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD37433.1 - 2.1e-05 25.5 0.0 4.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD37433.1 - 0.046 14.1 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 PVD37434.1 - 2.3e-41 142.0 1.0 1.1e-39 136.6 0.4 2.9 2 1 0 2 2 2 1 Trypsin DUF1986 PF09342.11 PVD37434.1 - 0.0045 17.3 1.7 0.014 15.8 1.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD37434.1 - 0.012 16.5 0.0 0.1 13.5 0.0 2.3 2 1 0 2 2 2 0 Trypsin-like peptidase domain Trypsin PF00089.26 PVD37435.1 - 1.1e-44 152.9 0.1 1.5e-42 145.9 0.1 2.3 1 1 0 1 1 1 1 Trypsin Ala_racemase_N PF01168.20 PVD37435.1 - 7e-11 42.2 0.1 5.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain DUF1986 PF09342.11 PVD37435.1 - 1.1e-07 32.2 0.1 2.3e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD37435.1 - 0.042 14.8 0.1 0.1 13.5 0.0 1.6 2 0 0 2 2 2 0 Trypsin-like peptidase domain LRR_6 PF13516.6 PVD37436.1 - 6.2e-13 47.7 14.4 0.0018 18.2 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 PVD37436.1 - 0.0053 17.1 3.2 18 6.4 0.1 5.5 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 PVD37436.1 - 0.0097 16.3 11.0 0.74 10.3 0.7 4.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD37436.1 - 0.8 9.5 12.4 1 9.2 0.9 4.7 3 2 0 3 3 3 0 Leucine rich repeat DUF1664 PF07889.12 PVD37436.1 - 7.8 6.6 40.0 1.3 9.0 1.4 5.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Sulfatase PF00884.23 PVD37437.1 - 5.5e-30 104.8 0.0 8.3e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 PVD37437.1 - 1.3e-09 38.2 2.8 2e-09 37.6 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 PVD37437.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.6 PVD37437.1 - 0.061 14.1 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 PVD37437.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 PVD37437.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfate_transp PF00916.20 PVD37442.1 - 1.2e-74 251.4 14.0 1.2e-74 251.4 14.0 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 PVD37442.1 - 2.7e-15 56.0 0.3 5.1e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 STAS domain VirB8 PF04335.13 PVD37443.1 - 0.022 14.6 0.2 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 VirB8 protein Sulfate_transp PF00916.20 PVD37444.1 - 1.3e-28 99.9 5.4 1.5e-26 93.1 5.4 2.2 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PVD37444.1 - 3e-15 55.9 0.1 4.3e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PVD37444.1 - 0.00036 20.8 0.0 0.00093 19.5 0.0 1.7 1 0 0 1 1 1 1 STAS domain DrsE_2 PF13686.6 PVD37444.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family T6PP_N PF18572.1 PVD37444.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Helicase_C PF00271.31 PVD37444.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF4010 PF13194.6 PVD37444.1 - 0.32 10.6 6.0 0.25 11.0 4.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4010) MFS_MOT1 PF16983.5 PVD37444.1 - 0.58 10.6 4.0 1.4 9.3 2.7 2.2 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily Trypsin PF00089.26 PVD37445.1 - 1.5e-95 319.2 1.2 8.9e-64 215.3 1.2 3.3 2 1 0 3 3 3 2 Trypsin CUB PF00431.20 PVD37445.1 - 2.5e-40 137.2 0.0 1.3e-23 83.4 0.0 2.6 2 0 0 2 2 2 2 CUB domain SRCR PF00530.18 PVD37445.1 - 8.5e-15 55.1 4.2 2.5e-14 53.6 4.2 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 PVD37445.1 - 2.2e-14 53.4 16.5 6e-08 32.8 8.3 3.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 PVD37445.1 - 2.4e-11 44.7 2.6 4.4e-06 27.7 0.2 3.6 3 0 0 3 3 3 2 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD37445.1 - 1.6e-06 28.4 0.3 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) CUB_2 PF02408.20 PVD37445.1 - 0.0018 18.0 0.2 0.21 11.4 0.0 2.8 3 0 0 3 3 3 1 CUB-like domain SRCR_2 PF15494.6 PVD37445.1 - 0.11 13.0 2.1 0.27 11.8 2.1 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37445.1 - 0.12 12.9 0.2 0.29 11.6 0.2 1.7 1 1 0 1 1 1 0 Hepsin, SRCR domain SRCR PF00530.18 PVD37446.1 - 1.5e-13 51.0 0.9 2.1e-13 50.6 0.9 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37446.1 - 1.7e-05 25.3 0.3 2.4e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37446.1 - 0.0086 16.6 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 Hepsin, SRCR domain 7tm_1 PF00001.21 PVD37447.1 - 1.2e-55 188.7 7.0 1.4e-55 188.4 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD37447.1 - 3.8e-12 46.4 13.1 5.4e-12 45.9 13.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD37447.1 - 6.7e-10 38.8 6.0 9.4e-10 38.3 6.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD37447.1 - 2.2e-08 34.2 7.7 5.2e-07 29.7 7.7 2.3 1 1 0 1 1 1 1 Olfactory receptor YajC PF02699.15 PVD37447.1 - 0.053 13.4 1.7 0.12 12.3 0.1 2.4 3 0 0 3 3 3 0 Preprotein translocase subunit TH1 PF04858.13 PVD37447.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 TH1 protein Serpentine_r_xa PF03383.15 PVD37447.1 - 0.88 9.5 6.4 0.13 12.2 0.3 2.6 3 1 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa tRNA_int_end_N2 PF12928.7 PVD37450.1 - 3.4e-14 52.8 0.2 1.2e-13 51.1 0.1 2.0 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 PVD37450.1 - 0.0011 18.6 0.0 0.0056 16.3 0.0 2.1 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain CytadhesinP1 PF12378.8 PVD37450.1 - 0.047 13.9 0.5 0.19 11.9 0.1 2.3 2 1 0 2 2 2 0 Trypsin-sensitive surface-exposed protein DHDPS PF00701.22 PVD37451.1 - 5.6e-20 71.2 0.0 1.7e-13 50.0 0.1 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family Peptidase_M15_3 PF08291.11 PVD37451.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 TIR_3 PF18567.1 PVD37453.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain Pex24p PF06398.11 PVD37455.1 - 6.4 5.6 5.0 7 5.5 5.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DBB PF14545.6 PVD37456.1 - 0.00097 19.1 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIG PF01833.24 PVD37456.1 - 0.0011 19.0 0.6 0.0036 17.3 0.6 1.8 1 0 0 1 1 1 1 IPT/TIG domain DUF4113 PF13438.6 PVD37456.1 - 0.012 15.7 0.1 39 4.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) GAS PF13851.6 PVD37458.1 - 0.0016 17.9 31.0 0.0016 17.9 31.0 7.6 3 2 3 7 7 7 3 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 PVD37458.1 - 0.08 12.8 0.1 0.08 12.8 0.1 8.9 9 1 1 10 10 10 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 PVD37458.1 - 0.15 11.5 113.1 0.0084 15.6 18.0 5.6 2 1 4 6 6 6 0 Golgin subfamily A member 5 Surfac_D-trimer PF09006.11 PVD37458.1 - 1.2 9.1 7.8 0.46 10.4 0.8 4.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3800 PF12686.7 PVD37458.1 - 1.4 9.6 4.8 6.3e+02 1.0 5.0 4.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) U-box PF04564.15 PVD37459.1 - 8.7e-28 96.3 0.1 1.6e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 PVD37459.1 - 2.2e-24 86.0 12.9 3.8e-24 85.2 12.9 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 PVD37459.1 - 2.1e-16 58.6 1.1 9.7e-05 22.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PVD37459.1 - 3.3e-16 58.3 2.2 4e-05 23.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PVD37459.1 - 8.3e-13 47.8 0.0 6.2e-08 32.2 0.2 3.3 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 PVD37459.1 - 8.8e-09 35.9 0.0 5.4e-07 30.2 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PVD37459.1 - 5.8e-08 32.9 2.1 0.0001 22.5 0.8 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD37459.1 - 1.2e-07 31.3 0.4 0.31 11.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD37459.1 - 1.6e-06 28.2 1.1 2.6e-06 27.6 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PVD37459.1 - 9.6e-06 25.3 1.6 0.056 13.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD37459.1 - 8.7e-05 23.0 0.0 0.3 12.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NRBF2_MIT PF17169.4 PVD37459.1 - 9.1e-05 22.6 0.4 0.0042 17.3 0.0 2.6 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 TPR_9 PF13371.6 PVD37459.1 - 0.00052 20.1 0.1 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD37459.1 - 0.00054 20.4 0.1 0.084 13.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PVD37459.1 - 0.0022 18.5 1.2 4.9 8.0 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PVD37459.1 - 0.012 15.9 0.2 0.13 12.7 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 PVD37459.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein MIT PF04212.18 PVD37459.1 - 0.015 15.3 1.6 0.84 9.7 0.1 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 PVD37459.1 - 0.38 10.9 3.5 4.3 7.4 0.0 3.0 3 0 0 3 3 3 0 MAS20 protein import receptor Thioredoxin_8 PF13905.6 PVD37460.1 - 4.9e-27 94.1 0.0 6.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PVD37460.1 - 7e-08 32.4 0.1 4.3e-05 23.4 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 PVD37460.1 - 7e-08 32.4 0.0 9.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PVD37460.1 - 5.4e-07 30.0 0.0 7.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 PVD37460.1 - 1.9e-06 27.6 0.0 2.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 PVD37460.1 - 0.024 14.8 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 PVD37461.1 - 3.5e-27 94.6 0.0 4.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PVD37461.1 - 3.4e-08 33.4 0.2 2.8e-05 24.0 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 PVD37461.1 - 6.5e-07 29.3 0.0 9.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PVD37461.1 - 2.1e-05 24.9 0.0 3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 PVD37461.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin Aminotran_3 PF00202.21 PVD37463.1 - 2.1e-78 263.8 0.0 2.7e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1615 PF07759.12 PVD37463.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) GTP_EFTU PF00009.27 PVD37464.1 - 2e-21 76.4 0.0 4.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PVD37464.1 - 2.5e-08 34.2 0.6 1.7e-07 31.6 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PVD37464.1 - 0.00025 21.1 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 PVD37464.1 - 0.0019 18.5 0.7 0.0077 16.5 0.3 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain Roc PF08477.13 PVD37464.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 PVD37464.1 - 0.014 15.1 0.0 9.5 6.0 0.0 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 PVD37464.1 - 0.034 13.6 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3408 PF11888.8 PVD37464.1 - 0.45 10.7 2.7 0.46 10.6 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Josephin PF02099.17 PVD37465.1 - 6.8e-27 94.6 0.0 5.2e-25 88.4 0.0 2.1 1 1 0 1 1 1 1 Josephin ITAM PF02189.15 PVD37466.1 - 0.062 13.8 4.6 29 5.4 0.1 3.9 2 2 2 4 4 4 0 Immunoreceptor tyrosine-based activation motif GAS PF13851.6 PVD37467.1 - 0.0065 15.9 1.4 0.0081 15.5 1.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 PVD37467.1 - 0.019 15.1 1.0 0.033 14.3 1.0 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 PVD37467.1 - 0.037 14.9 3.0 0.053 14.4 3.0 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Bap31_Bap29_C PF18035.1 PVD37467.1 - 0.045 13.8 3.2 0.074 13.1 3.2 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc24 PF08286.11 PVD37467.1 - 0.057 13.7 0.2 0.063 13.5 0.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 PVD37467.1 - 0.081 12.7 3.3 0.12 12.1 3.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DBC1 PF14443.6 PVD37468.1 - 2e-39 134.4 0.0 8e-39 132.5 0.0 2.1 1 0 0 1 1 1 1 DBC1 S1-like PF14444.6 PVD37468.1 - 4.2e-32 109.9 0.3 8.5e-32 108.9 0.3 1.6 1 0 0 1 1 1 1 S1-like SAP PF02037.27 PVD37468.1 - 6.6e-09 35.3 2.0 1.5e-08 34.2 2.0 1.6 1 0 0 1 1 1 1 SAP domain NDUFB10 PF10249.9 PVD37469.1 - 3.3e-45 153.7 7.5 3.9e-45 153.4 7.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Nup54_57_C PF18570.1 PVD37469.1 - 0.013 15.0 0.6 0.039 13.5 0.6 1.8 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain DUF4993 PF16384.5 PVD37469.1 - 0.17 10.8 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_L3 PF00297.22 PVD37470.1 - 3.5e-173 575.8 12.3 4.5e-173 575.4 12.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 AJAP1_PANP_C PF15298.6 PVD37471.1 - 0.0045 17.2 0.1 0.0055 16.9 0.1 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus COX2_TM PF02790.15 PVD37471.1 - 0.05 13.8 0.9 0.066 13.4 0.3 1.6 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain ODV-E18 PF10717.9 PVD37471.1 - 0.14 12.1 1.6 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ECSCR PF15820.5 PVD37471.1 - 2.1 8.2 4.3 16 5.4 2.2 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Phage_TAC_12 PF12363.8 PVD37472.1 - 0.0082 16.6 0.1 0.53 10.7 0.0 2.9 1 1 2 3 3 3 1 Phage tail assembly chaperone protein, TAC ApoLp-III PF07464.11 PVD37473.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) VKG_Carbox PF05090.14 PVD37474.1 - 2.6e-123 412.1 10.7 3.5e-123 411.7 10.7 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase E_raikovi_mat PF06360.11 PVD37474.1 - 0.064 13.7 0.4 0.12 12.8 0.4 1.4 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone DUF4472 PF14739.6 PVD37476.1 - 5.6 7.8 12.8 2.1 9.1 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) fn3 PF00041.21 PVD37479.1 - 3.8e-06 27.1 0.2 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain MbeB_N PF04837.12 PVD37479.1 - 0.0013 18.9 0.6 0.0028 17.9 0.6 1.5 1 0 0 1 1 1 1 MbeB-like, N-term conserved region Pur_ac_phosph_N PF16656.5 PVD37479.1 - 0.0039 17.7 1.4 0.0096 16.5 0.0 2.3 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Apolipoprotein PF01442.18 PVD37479.1 - 0.021 14.7 2.3 0.036 13.9 2.3 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PVD37479.1 - 0.026 14.5 1.9 0.05 13.6 1.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.6 PVD37479.1 - 0.049 13.5 1.4 0.085 12.7 1.4 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate TIG PF01833.24 PVD37479.1 - 0.082 13.0 0.1 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 IPT/TIG domain FUSC PF04632.12 PVD37479.1 - 0.16 10.5 0.6 0.22 10.0 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spectrin PF00435.21 PVD37479.1 - 4 8.0 6.6 26 5.4 0.0 2.9 2 1 1 3 3 3 0 Spectrin repeat PP28 PF10252.9 PVD37480.1 - 3.7e-26 91.4 17.0 3.7e-26 91.4 17.0 2.5 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 zf-CCCH PF00642.24 PVD37481.1 - 9e-16 57.4 32.4 6.5e-06 25.9 0.3 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD37481.1 - 7.8e-12 44.8 46.7 2.4e-06 27.4 2.0 6.1 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 PVD37481.1 - 6.5e-11 42.9 27.3 0.00076 20.1 0.3 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 PVD37481.1 - 2.5e-10 40.5 23.2 4.9e-10 39.6 7.9 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 PVD37481.1 - 4.1e-06 27.0 43.8 0.11 13.1 1.5 5.8 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PVD37481.1 - 5e-05 23.0 0.4 5e-05 23.0 0.4 4.6 4 0 0 4 4 4 1 CCCH-type zinc finger Arrestin_N PF00339.29 PVD37482.1 - 1e-08 35.4 0.0 7.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PVD37482.1 - 7.9e-08 32.8 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain IF3_C PF00707.22 PVD37482.1 - 0.14 12.2 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Abhydrolase_3 PF07859.13 PVD37483.1 - 2.4e-15 57.0 0.1 8.7e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 PVD37483.1 - 2.8e-11 43.0 0.0 7.1e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 PVD37483.1 - 2e-09 37.2 0.0 1.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PVD37483.1 - 7.3e-06 25.4 0.0 0.025 13.9 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD37483.1 - 0.0015 19.2 1.5 0.59 10.7 0.1 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PVD37483.1 - 0.0022 17.8 0.1 0.091 12.6 0.0 2.7 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PVD37483.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 PVD37483.1 - 0.024 14.3 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 PVD37483.1 - 0.057 13.0 0.0 0.33 10.4 0.0 2.1 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase DUF2920 PF11144.8 PVD37483.1 - 0.079 12.1 0.1 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 PVD37483.1 - 0.13 11.9 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pkinase PF00069.25 PVD37484.1 - 3e-64 216.9 0.0 4.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD37484.1 - 7.7e-29 100.8 0.0 1.1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD37484.1 - 3.1e-06 26.7 0.3 5.5e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD37484.1 - 0.00035 20.6 0.1 0.00081 19.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PVD37484.1 - 0.00042 20.0 0.2 0.00084 19.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PVD37484.1 - 0.00047 19.6 0.0 0.00085 18.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PVD37484.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PVD37484.1 - 0.14 11.1 0.1 0.42 9.5 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RhoGAP PF00620.27 PVD37485.1 - 3.8e-42 143.7 0.7 5.9e-42 143.1 0.1 1.6 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 PVD37485.1 - 1.7e-16 60.6 0.5 3.6e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PVD37485.1 - 0.005 17.2 0.2 0.046 14.1 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain GBP_C PF02841.14 PVD37485.1 - 0.015 14.8 1.9 0.029 13.8 1.9 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain BBP1_C PF15272.6 PVD37485.1 - 0.018 14.9 1.1 0.044 13.6 1.1 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Zein-binding PF04576.15 PVD37485.1 - 0.044 14.1 0.7 0.044 14.1 0.7 2.5 2 0 0 2 2 2 0 Zein-binding Rootletin PF15035.6 PVD37485.1 - 0.06 13.4 4.3 0.16 12.0 4.3 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3135 PF11333.8 PVD37485.1 - 0.66 10.3 4.2 0.62 10.4 1.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) RB_A PF01858.17 PVD37485.1 - 1.4 8.7 5.2 0.5 10.2 1.8 1.9 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain FAM76 PF16046.5 PVD37485.1 - 5.4 6.3 9.0 12 5.1 9.0 1.6 1 1 0 1 1 1 0 FAM76 protein DEAD PF00270.29 PVD37486.1 - 3.1e-50 170.4 0.0 6.2e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37486.1 - 4.7e-26 91.3 0.0 3.3e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CdAMP_rec PF06153.11 PVD37486.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 Cyclic-di-AMP receptor 7tm_2 PF00002.24 PVD37487.1 - 7.2e-10 38.6 13.1 1.2e-09 37.8 13.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) AOX PF01786.17 PVD37487.1 - 0.89 9.1 4.5 0.39 10.3 0.4 2.0 1 1 0 2 2 2 0 Alternative oxidase GWT1 PF06423.12 PVD37487.1 - 3 7.9 7.4 11 6.1 7.4 1.8 1 1 0 1 1 1 0 GWT1 DUF2975 PF11188.8 PVD37487.1 - 3.1 7.7 12.5 0.95 9.4 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Toxin_19 PF08088.12 PVD37488.1 - 5.8 7.1 12.5 1.5 9.0 7.3 2.8 2 1 0 2 2 2 0 Conotoxin I-superfamily 7tm_2 PF00002.24 PVD37490.1 - 2.3e-12 46.7 16.0 3.9e-12 46.0 16.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cation_ATPase_C PF00689.21 PVD37490.1 - 0.1 12.3 11.5 0.39 10.4 11.3 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF4448 PF14610.6 PVD37490.1 - 0.13 12.1 4.1 11 5.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) GPI2 PF06432.11 PVD37490.1 - 2.4 7.6 13.2 0.36 10.2 0.4 2.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase SKG6 PF08693.10 PVD37490.1 - 3.3 7.2 8.6 13 5.3 2.9 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain 7tm_2 PF00002.24 PVD37491.1 - 1.8e-11 43.8 19.2 1.8e-11 43.8 19.2 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Pardaxin PF07425.11 PVD37491.1 - 0.03 13.9 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 Pardaxin GPI2 PF06432.11 PVD37491.1 - 0.17 11.3 13.6 55 3.1 13.6 2.5 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase COS PF18568.1 PVD37494.1 - 0.031 14.2 1.5 4 7.5 0.3 2.5 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain 7tm_2 PF00002.24 PVD37495.1 - 7.5e-06 25.4 0.3 1.1e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) SKG6 PF08693.10 PVD37495.1 - 0.58 9.6 7.4 2.4 7.6 3.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 PVD37495.1 - 0.6 9.9 3.1 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Ephrin_rec_like PF07699.13 PVD37497.1 - 2.5e-121 395.3 247.6 5.5e-10 38.9 6.3 19.9 19 0 0 19 19 17 17 Putative ephrin-receptor like EGF PF00008.27 PVD37497.1 - 3.6e-65 215.8 276.9 3.8e-08 33.5 4.3 22.0 20 1 1 21 21 19 15 EGF-like domain CUB PF00431.20 PVD37497.1 - 1.8e-39 134.4 0.3 7.1e-21 74.6 0.0 4.1 4 0 0 4 4 3 3 CUB domain hEGF PF12661.7 PVD37497.1 - 7.1e-37 124.8 213.4 5.7e-05 23.6 4.7 22.8 18 1 1 19 19 19 13 Human growth factor-like EGF Sushi PF00084.20 PVD37497.1 - 6.1e-19 68.4 91.7 1.4e-09 38.4 0.1 15.2 14 2 1 15 15 13 6 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 PVD37497.1 - 1.1e-12 48.0 24.5 8e-09 35.6 7.5 30.9 16 8 14 31 31 22 6 Coagulation Factor Xa inhibitory site Laminin_G_3 PF13385.6 PVD37497.1 - 1.6e-09 38.1 0.9 4.6e-09 36.6 0.9 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.7 PVD37497.1 - 2.9e-07 30.3 6.5 6.9e-07 29.1 2.0 28.2 29 0 0 29 29 29 5 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD37497.1 - 6.9e-07 29.4 8.1 6.9e-07 29.4 8.1 29.0 18 6 9 27 27 21 7 Calcium-binding EGF domain CUB_2 PF02408.20 PVD37497.1 - 1.6e-06 27.9 0.1 0.027 14.2 0.0 3.2 2 0 0 2 2 2 2 CUB-like domain EGF_3 PF12947.7 PVD37497.1 - 0.00028 21.0 6.9 0.00028 21.0 6.9 21.9 20 3 2 22 22 22 8 EGF domain PAN_4 PF14295.6 PVD37498.1 - 0.00049 20.0 4.5 0.13 12.2 1.0 2.6 2 0 0 2 2 2 2 PAN domain EphA2_TM PF14575.6 PVD37498.1 - 0.0038 18.1 0.2 0.46 11.4 0.0 2.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD37498.1 - 0.0047 16.8 5.8 0.0047 16.8 5.8 3.6 4 1 0 4 4 3 1 TMEM154 protein family PAN_2 PF08276.11 PVD37498.1 - 0.013 15.6 7.8 0.43 10.7 1.3 2.9 1 1 1 2 2 2 0 PAN-like domain FRB_dom PF08771.11 PVD37498.1 - 0.027 14.9 1.6 0.051 14.0 0.9 1.8 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain MtrF PF09472.10 PVD37498.1 - 0.085 12.3 1.5 0.17 11.3 1.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) OAD_gamma PF04277.13 PVD37498.1 - 0.094 13.3 0.0 0.32 11.6 0.0 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AJAP1_PANP_C PF15298.6 PVD37498.1 - 0.11 12.7 22.5 0.032 14.4 6.1 3.4 3 0 0 3 3 3 0 AJAP1/PANP C-terminus PAN_1 PF00024.26 PVD37498.1 - 0.17 11.9 21.1 0.073 13.1 1.7 3.5 2 1 1 3 3 2 0 PAN domain T2SSM PF04612.12 PVD37498.1 - 0.19 11.7 1.7 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Orf78 PF06024.12 PVD37498.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.9 4 1 0 5 5 4 0 Orf78 (ac78) Mucin PF01456.17 PVD37498.1 - 1.5 8.8 53.2 0.084 12.9 7.1 3.3 4 0 0 4 4 4 0 Mucin-like glycoprotein LapA_dom PF06305.11 PVD37498.1 - 3.4 7.5 5.4 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain YajC PF02699.15 PVD37498.1 - 4 7.4 6.4 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit DUF3742 PF12553.8 PVD37499.1 - 0.0056 16.8 1.0 0.0072 16.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3742) ABC_membrane PF00664.23 PVD37499.1 - 0.015 15.0 2.4 0.02 14.6 2.4 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF5305 PF17231.2 PVD37499.1 - 0.054 12.9 1.2 0.079 12.3 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SIT PF15330.6 PVD37499.1 - 0.071 13.6 1.7 0.11 12.9 1.7 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 PVD37499.1 - 0.13 12.2 2.8 0.2 11.6 2.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 PVD37499.1 - 0.16 10.8 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless HemY_N PF07219.13 PVD37499.1 - 0.19 11.9 2.6 0.32 11.2 2.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus GRP PF07172.11 PVD37499.1 - 0.27 11.9 1.1 0.48 11.1 1.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family Lectin_N PF03954.14 PVD37499.1 - 0.51 10.1 3.5 0.91 9.3 3.5 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain ECSCR PF15820.5 PVD37499.1 - 0.76 9.6 2.5 1.4 8.8 2.5 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Baculo_11_kDa PF06143.11 PVD37499.1 - 1.7 8.3 6.9 2.8 7.6 6.9 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF805 PF05656.14 PVD37499.1 - 2.8 8.4 4.6 4.4 7.8 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Thiol_cytolysin PF01289.19 PVD37500.1 - 0.021 13.7 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin Astacin PF01400.24 PVD37502.1 - 4.3e-61 205.9 0.1 8.4e-61 204.9 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 PVD37502.1 - 8.7e-27 93.4 79.6 6.8e-09 36.1 10.1 6.9 7 0 0 7 7 5 4 ShK domain-like PAN_3 PF08277.12 PVD37502.1 - 1e-19 70.1 39.8 0.00064 19.5 0.4 8.1 7 0 0 7 7 7 6 PAN-like domain PAN_4 PF14295.6 PVD37502.1 - 2.4e-11 43.4 73.4 0.00029 20.7 0.7 9.9 9 2 1 10 10 10 7 PAN domain Peptidase_M10 PF00413.24 PVD37502.1 - 1.5e-05 24.9 0.3 0.01 15.7 0.1 2.6 3 0 0 3 3 3 2 Matrixin MANEC PF07502.14 PVD37502.1 - 0.00011 22.4 32.5 1.5 9.1 0.2 7.8 7 0 0 7 7 7 4 MANEC domain Peptidase_M66 PF10462.9 PVD37502.1 - 0.00013 21.1 0.1 0.00024 20.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 PVD37502.1 - 0.0033 17.9 0.1 0.011 16.3 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PAN_2 PF08276.11 PVD37502.1 - 0.0036 17.4 2.3 0.0036 17.4 2.3 7.8 7 0 0 7 7 7 2 PAN-like domain DUF4953 PF16313.5 PVD37502.1 - 0.034 13.3 0.3 0.056 12.7 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 PVD37502.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 PVD37502.1 - 1.3 9.0 3.8 0.33 10.9 0.2 1.8 2 0 0 2 2 2 0 Peptidase family M54 EphA2_TM PF14575.6 PVD37503.1 - 0.085 13.8 0.1 0.12 13.3 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BCMA-Tall_bind PF09257.10 PVD37505.1 - 1.6e-06 28.1 10.3 0.0045 17.1 2.0 3.0 2 1 0 2 2 2 2 BCMA, TALL-1 binding CPDase PF07823.11 PVD37505.1 - 0.11 12.2 0.0 0.84 9.3 0.0 2.0 1 1 1 2 2 2 0 Cyclic phosphodiesterase-like protein TACI-CRD2 PF09305.10 PVD37505.1 - 0.3 11.2 15.7 0.1 12.6 2.4 3.0 2 1 0 2 2 2 0 TACI, cysteine-rich domain PRIMA1 PF16101.5 PVD37506.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 TMEM154 PF15102.6 PVD37506.1 - 0.0005 20.0 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 PVD37506.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 PVD37506.1 - 0.02 13.7 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LPG_synthase_TM PF03706.13 PVD37506.1 - 0.037 13.5 0.0 0.046 13.2 0.0 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TACI-CRD2 PF09305.10 PVD37506.1 - 6.1 7.0 15.8 0.27 11.3 7.4 2.4 2 0 0 2 2 2 0 TACI, cysteine-rich domain BCMA-Tall_bind PF09257.10 PVD37507.1 - 0.00032 20.7 16.5 0.015 15.4 2.3 2.8 2 1 0 2 2 2 2 BCMA, TALL-1 binding TACI-CRD2 PF09305.10 PVD37507.1 - 0.034 14.2 7.7 0.034 14.2 7.7 2.7 2 1 0 2 2 2 0 TACI, cysteine-rich domain Peptidase_C14 PF00656.22 PVD37508.1 - 3.7e-42 145.0 0.0 6.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 PVD37509.1 - 2.2e-29 103.2 0.0 2.8e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain tRNA-synt_1g PF09334.11 PVD37509.1 - 0.024 13.4 0.1 0.038 12.8 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) 7tm_1 PF00001.21 PVD37510.1 - 1.3e-34 119.7 0.5 1.3e-34 119.7 0.5 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD37510.1 - 2.2e-06 27.3 6.8 3.6e-06 26.6 6.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD37510.1 - 0.0017 18.1 5.8 0.0017 18.1 5.8 1.4 2 0 0 2 2 2 1 Olfactory receptor Git3 PF11710.8 PVD37510.1 - 0.02 14.7 11.5 0.027 14.3 11.5 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Pex14_N PF04695.13 PVD37511.1 - 0.058 14.1 0.2 0.065 13.9 0.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VWD PF00094.25 PVD37513.1 - 1.7e-34 119.3 0.1 2.9e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 PVD37513.1 - 9.8e-24 83.4 126.8 9.2e-11 41.9 15.6 8.1 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.11 PVD37513.1 - 2.4e-11 43.9 9.9 2.4e-11 43.9 9.9 4.4 4 2 0 4 4 4 1 C8 domain TIL PF01826.17 PVD37513.1 - 8.7e-10 38.7 14.3 8.7e-10 38.7 14.3 8.6 4 2 1 5 5 5 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 PVD37513.1 - 0.016 15.2 6.0 0.016 15.2 6.0 9.0 9 1 0 9 9 9 0 TILa domain Glycos_transf_2 PF00535.26 PVD37514.1 - 4.2e-21 75.5 0.0 6.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PVD37514.1 - 4e-12 46.5 0.0 5.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PVD37514.1 - 7.8e-08 32.1 0.1 1e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PVD37514.1 - 0.0001 22.7 0.0 0.0013 19.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 CAP59_mtransfer PF11735.8 PVD37514.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Glyco_trans_2_3 PF13632.6 PVD37514.1 - 0.063 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 RVT_1 PF00078.27 PVD37515.1 - 2.4e-06 27.2 0.0 5.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Whi5 PF08528.11 PVD37517.1 - 0.002 17.7 0.1 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Whi5 like RGI1 PF10843.8 PVD37517.1 - 0.0045 16.7 0.2 0.4 10.3 0.0 2.4 1 1 1 2 2 2 2 Respiratory growth induced protein 1 DUF4773 PF15998.5 PVD37519.1 - 7.3e-27 94.2 7.5 1e-26 93.7 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) APA3_viroporin PF11289.8 PVD37520.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus accessory protein 3a DUF4773 PF15998.5 PVD37521.1 - 3.8e-20 72.6 1.9 5.3e-20 72.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) DUF4773 PF15998.5 PVD37522.1 - 2.9e-24 85.8 5.7 5e-24 85.1 5.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Radial_spoke PF04712.12 PVD37523.1 - 1.9e-116 389.9 0.0 1.2e-73 248.8 0.0 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein TCTP PF00838.17 PVD37524.1 - 0.017 15.5 0.3 0.045 14.1 0.0 1.7 2 0 0 2 2 2 0 Translationally controlled tumour protein Tom22 PF04281.13 PVD37524.1 - 0.041 13.7 0.4 0.1 12.4 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 partial_CstF PF15861.5 PVD37524.1 - 0.06 13.2 3.2 0.15 11.9 3.2 1.7 1 1 0 1 1 1 0 Partial cleavage stimulation factor domain DUF2569 PF10754.9 PVD37524.1 - 0.52 10.7 6.8 0.62 10.5 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) TMC PF07810.13 PVD37525.1 - 4e-18 66.0 11.9 7.8e-09 36.1 2.4 3.4 2 1 1 3 3 3 2 TMC domain Dzip-like_N PF13815.6 PVD37525.1 - 0.2 11.6 0.5 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF1977 PF09320.11 PVD37526.1 - 2.5e-29 101.6 1.6 5.4e-29 100.5 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 PVD37526.1 - 4.9e-24 84.2 2.4 6.1e-24 83.9 1.3 1.8 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 PVD37526.1 - 0.0016 18.2 0.0 0.24 11.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PVD37526.1 - 0.0043 17.1 0.5 0.1 12.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PVD37526.1 - 0.046 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD37526.1 - 0.11 13.4 0.2 1.3 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 PVD37526.1 - 0.11 12.4 1.7 0.17 11.8 1.4 1.7 1 1 0 1 1 1 0 YfdX protein RRM_1 PF00076.22 PVD37527.1 - 9.9e-14 50.9 0.1 1.7e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PVD37527.1 - 6.9e-06 26.0 0.1 1.1e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PVD37527.1 - 1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 PVD37527.1 - 0.0075 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 PVD37528.1 - 5.5e-14 51.7 0.1 9e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PVD37528.1 - 2.8e-06 27.2 1.8 2.8e-06 27.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 PVD37528.1 - 3.4e-06 27.7 0.1 7.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 PVD37528.1 - 2.7e-05 24.1 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PVD37528.1 - 8.1e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 PVD37528.1 - 0.0019 18.1 1.8 0.0019 18.1 1.8 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PVD37528.1 - 0.0059 16.4 1.8 0.013 15.3 1.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 PVD37528.1 - 0.007 16.6 0.2 0.02 15.1 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 PVD37528.1 - 0.012 16.1 0.5 0.012 16.1 0.5 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 PVD37528.1 - 0.022 14.8 0.2 0.05 13.6 0.1 1.6 2 0 0 2 2 2 0 RNA binding motif zinc-ribbons_6 PF07191.12 PVD37528.1 - 0.52 10.3 6.1 1.1 9.3 6.1 1.5 1 0 0 1 1 1 0 zinc-ribbons Hairy_orange PF07527.13 PVD37529.1 - 1.8e-10 40.9 0.1 5.2e-10 39.4 0.1 1.9 1 0 0 1 1 1 1 Hairy Orange TFIID_30kDa PF03540.13 PVD37529.1 - 0.022 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DUF3504 PF12012.8 PVD37532.1 - 0.087 12.7 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Syndecan PF01034.20 PVD37534.1 - 0.31 11.0 0.7 0.5 10.3 0.7 1.2 1 0 0 1 1 1 0 Syndecan domain N_methyl PF07963.12 PVD37534.1 - 0.84 9.3 5.1 1.2 8.8 5.1 1.2 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Ldl_recept_a PF00057.18 PVD37535.1 - 0.0067 16.6 1.0 0.0067 16.6 1.0 1.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 PVD37536.1 - 5.5e-15 55.3 22.2 4.1e-06 26.9 4.1 4.0 3 1 1 4 4 4 3 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD37536.1 - 1.3e-12 47.3 23.7 1.5e-07 31.1 0.4 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PVD37536.1 - 5.9e-09 36.1 24.9 0.0071 16.7 8.4 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 PVD37536.1 - 1.1e-08 34.7 11.2 1.1e-08 34.7 11.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.6 PVD37536.1 - 0.011 15.8 10.4 0.25 11.5 0.2 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Laps PF10169.9 PVD37536.1 - 0.21 12.1 3.0 0.37 11.4 3.0 1.3 1 0 0 1 1 1 0 Learning-associated protein DC_STAMP PF07782.13 PVD37536.1 - 6.6 6.5 7.6 2 8.2 1.9 2.5 2 0 0 2 2 2 0 DC-STAMP-like protein Ldl_recept_a PF00057.18 PVD37537.1 - 3.5e-08 33.5 36.9 0.0067 16.6 2.4 6.1 6 0 0 6 6 6 3 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 PVD37537.1 - 0.0056 16.4 0.1 0.0056 16.4 0.1 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PVD37537.1 - 0.87 10.1 4.0 0.66 10.5 0.4 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) fn3 PF00041.21 PVD37538.1 - 6.1e-35 119.4 12.7 1.1e-11 44.9 0.6 5.2 4 1 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.6 PVD37538.1 - 1.7e-24 86.2 0.9 3.6e-08 33.9 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain DB PF01682.19 PVD37538.1 - 2.8e-19 69.2 35.0 3.1e-12 46.6 11.9 3.6 2 2 2 4 4 4 4 DB module I-set PF07679.16 PVD37538.1 - 1.3e-18 66.8 1.3 7.3e-07 29.2 0.0 4.7 5 1 0 5 5 5 2 Immunoglobulin I-set domain V-set PF07686.17 PVD37538.1 - 2.5e-16 59.8 2.2 1.8e-08 34.5 0.0 4.3 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 PVD37538.1 - 5.8e-16 58.6 0.6 0.00065 20.0 0.0 5.0 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 PVD37538.1 - 2.2e-15 56.6 1.7 0.00082 19.5 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 PVD37538.1 - 3.3e-05 24.1 0.4 0.0074 16.5 0.0 4.0 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD37538.1 - 0.00076 19.5 0.2 4.8 7.3 0.0 4.1 3 1 1 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD37538.1 - 0.12 12.0 2.6 4.5 6.9 0.0 3.6 4 0 0 4 4 4 0 Immunoglobulin domain Ig_5 PF16681.5 PVD37538.1 - 0.12 12.8 3.8 0.32 11.4 0.0 3.6 4 2 0 4 4 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Peptidase_M28 PF04389.17 PVD37540.1 - 2.8e-06 27.1 0.6 0.00029 20.6 0.1 2.4 1 1 0 2 2 2 2 Peptidase family M28 ADP_ribosyl_GH PF03747.14 PVD37541.1 - 5e-54 184.0 2.1 5.9e-54 183.8 2.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Xpo1 PF08389.12 PVD37542.1 - 1.9e-16 60.4 0.2 1.9e-16 60.4 0.2 6.0 6 2 2 8 8 8 1 Exportin 1-like protein Phage_int_SAM_5 PF13102.6 PVD37542.1 - 0.36 11.2 1.9 1.5 9.2 0.3 2.6 2 0 0 2 2 2 0 Phage integrase SAM-like domain Glyco_hydro_18 PF00704.28 PVD37543.1 - 7.1e-167 554.8 0.1 3.6e-85 286.4 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD37543.1 - 1.8e-23 82.4 17.4 2.4e-12 46.8 4.3 2.8 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 PVD37544.1 - 1.9e-78 264.4 0.0 2.5e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD37544.1 - 2.9e-19 69.0 9.0 1.4e-13 50.8 1.8 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD37545.1 - 4.4e-28 97.2 17.1 1.1e-14 54.3 4.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 PVD37546.1 - 9.3e-90 301.5 0.2 1.1e-89 301.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 hNIFK_binding PF12196.8 PVD37546.1 - 0.15 11.6 1.7 0.29 10.6 1.7 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Glyco_hydro_18 PF00704.28 PVD37547.1 - 2.9e-53 181.6 0.0 4.2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD37547.1 - 2.1e-14 53.4 4.2 5e-14 52.2 4.2 1.7 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 PVD37548.1 - 1.5e-237 787.0 1.5 5.4e-86 289.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD37548.1 - 1.1e-10 41.5 0.4 2.5e-10 40.3 0.4 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain YuzL PF14115.6 PVD37548.1 - 0.009 16.5 0.5 15 6.2 0.0 3.5 3 0 0 3 3 3 1 YuzL-like protein PRD PF00874.20 PVD37548.1 - 0.042 14.2 0.7 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 PRD domain DUF4734 PF15881.5 PVD37548.1 - 0.15 12.2 0.4 53 4.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) zf-RING_UBOX PF13445.6 PVD37549.1 - 1.3e-12 47.5 5.1 1.3e-12 47.5 5.1 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD37549.1 - 1.2e-09 37.9 5.9 1.2e-09 37.9 5.9 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 PVD37549.1 - 2.1e-08 34.1 6.3 2.1e-08 34.1 6.3 3.2 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.6 PVD37549.1 - 3.8e-08 33.1 6.1 3.8e-08 33.1 6.1 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD37549.1 - 5e-08 32.7 2.5 5e-08 32.7 2.5 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD37549.1 - 5.3e-08 33.1 6.8 5.3e-08 33.1 6.8 3.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 PVD37549.1 - 1.5e-07 31.4 7.7 1.5e-07 31.4 7.7 3.2 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PVD37549.1 - 2.4e-07 30.5 3.8 2.4e-07 30.5 3.8 3.7 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD37549.1 - 1e-05 25.3 4.6 1e-05 25.3 4.6 3.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PVD37549.1 - 0.0008 19.1 4.8 0.0008 19.1 4.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger Glutaredoxin2_C PF04399.13 PVD37549.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Spore_III_AB PF09548.10 PVD37549.1 - 0.11 12.6 2.0 0.2 11.7 2.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Methyltransf_32 PF13679.6 PVD37549.1 - 0.25 11.3 6.4 1.8 8.5 6.4 2.1 1 1 0 1 1 1 0 Methyltransferase domain ERM PF00769.19 PVD37549.1 - 0.38 10.5 13.6 0.64 9.8 13.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.12 PVD37549.1 - 5 5.5 9.9 6.6 5.1 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FYVE_2 PF02318.16 PVD37549.1 - 9.6 6.4 26.2 0.17 12.1 1.3 3.4 2 1 0 3 3 3 0 FYVE-type zinc finger ER_lumen_recept PF00810.18 PVD37550.1 - 4.6e-56 189.7 8.7 4.6e-56 189.7 8.7 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor HGTP_anticodon PF03129.20 PVD37551.1 - 3.8e-13 49.4 0.0 6.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Septin PF00735.18 PVD37551.1 - 0.095 12.0 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Septin Lipase_3 PF01764.25 PVD37552.1 - 2.5e-13 50.1 0.0 4.7e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PVD37552.1 - 0.12 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1180 PF06679.12 PVD37556.1 - 0.063 13.7 0.1 0.093 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SAM_1 PF00536.30 PVD37557.1 - 3.4e-10 40.2 0.0 5.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD37557.1 - 6e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD37557.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAND PF01342.21 PVD37558.1 - 6.5e-23 80.2 0.6 2.1e-22 78.6 0.1 2.0 2 0 0 2 2 2 1 SAND domain Chitin_synth_2 PF03142.15 PVD37559.1 - 2.5e-35 122.1 6.2 1.2e-31 110.0 0.2 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD37559.1 - 1.2e-10 41.6 5.2 2.3e-10 40.7 4.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD37559.1 - 1.1e-06 28.7 0.2 5.1e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Tti2 PF10521.9 PVD37559.1 - 0.26 10.8 1.1 0.61 9.6 1.1 1.6 1 0 0 1 1 1 0 Tti2 family Hid1 PF12722.7 PVD37559.1 - 4.6 5.3 7.3 12 3.9 7.3 1.6 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DEAD PF00270.29 PVD37561.1 - 3.5e-49 166.9 0.0 1.3e-48 165.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37561.1 - 5.4e-31 107.2 0.1 3.3e-30 104.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD37561.1 - 4.1e-05 23.6 0.0 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PVD37561.1 - 0.0017 17.6 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ephrin_rec_like PF07699.13 PVD37562.1 - 2e-82 270.7 171.5 4.2e-09 36.0 5.1 17.1 1 1 19 20 20 20 20 Putative ephrin-receptor like SRCR PF00530.18 PVD37562.1 - 4.4e-24 84.9 1.7 4.4e-24 84.9 1.7 3.9 3 1 1 4 4 4 1 Scavenger receptor cysteine-rich domain NCD3G PF07562.14 PVD37562.1 - 2.4e-19 69.1 127.6 0.0099 15.8 5.8 14.0 3 2 12 18 18 18 17 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 PVD37562.1 - 6.1e-09 35.2 116.1 0.005 15.8 17.6 7.3 1 1 6 7 7 7 7 Giardia variant-specific surface protein TNFR_c6 PF00020.18 PVD37562.1 - 0.014 15.8 132.1 0.86 10.1 0.4 18.3 6 4 13 20 20 20 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 PVD37563.1 - 3.8e-226 730.9 470.3 1.2e-09 37.8 8.2 39.9 3 2 40 43 43 43 42 Putative ephrin-receptor like VSP PF03302.13 PVD37563.1 - 6.1e-16 58.3 309.8 0.019 13.9 20.6 16.0 2 2 11 13 13 13 13 Giardia variant-specific surface protein TNFR_c6 PF00020.18 PVD37563.1 - 5.8e-13 49.0 352.5 0.13 12.6 1.7 43.6 15 8 21 40 40 40 27 TNFR/NGFR cysteine-rich region AbrB PF05145.12 PVD37563.1 - 7.9e-05 21.8 0.6 13 4.6 0.0 6.0 4 2 3 8 8 8 2 Transition state regulatory protein AbrB GalKase_gal_bdg PF10509.9 PVD37563.1 - 0.00049 19.6 7.9 2.9e+02 1.1 0.0 12.3 9 4 2 12 12 12 0 Galactokinase galactose-binding signature DUF4692 PF15763.5 PVD37563.1 - 0.1 13.1 0.6 0.74 10.3 0.0 2.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Ppnp PF06865.11 PVD37564.1 - 0.013 15.9 2.8 17 5.9 0.0 4.0 1 1 2 4 4 4 0 Pyrimidine/purine nucleoside phosphorylase Dabb PF07876.12 PVD37564.1 - 1.1 9.9 8.6 1.1 9.9 0.4 2.9 2 1 0 2 2 2 0 Stress responsive A/B Barrel Domain Pkinase_Tyr PF07714.17 PVD37566.1 - 2.1e-37 128.8 0.0 3.2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37566.1 - 2.3e-33 115.7 0.0 3.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 PVD37566.1 - 2.9e-15 55.4 0.3 6.6e-15 54.3 0.3 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif LRR19-TM PF15176.6 PVD37566.1 - 0.022 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF3827 PF12877.7 PVD37566.1 - 0.034 12.5 0.1 0.051 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Haspin_kinase PF12330.8 PVD37566.1 - 0.057 12.4 0.0 0.28 10.1 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 PVD37566.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Methyltransf_25 PF13649.6 PVD37568.1 - 2.3e-14 53.9 0.0 3.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD37568.1 - 5.5e-14 52.6 0.0 8.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PVD37568.1 - 2.7e-08 33.5 0.0 1e-07 31.5 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PVD37568.1 - 3e-08 34.3 0.0 4.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD37568.1 - 0.00034 20.5 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PVD37568.1 - 0.00088 19.1 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PVD37568.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 PVD37568.1 - 0.038 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin p450 PF00067.22 PVD37569.1 - 6e-92 308.8 0.0 6.8e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD37570.1 - 1.5e-96 324.0 0.0 1.7e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD37571.1 - 2.4e-100 336.5 0.0 2.7e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD37572.1 - 1.2e-85 288.0 0.0 1.5e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD37573.1 - 2.2e-161 537.7 0.0 1.7e-99 333.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SPASM PF13186.6 PVD37573.1 - 0.026 15.1 0.0 4.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain DUF3719 PF12516.8 PVD37575.1 - 3.6e-13 49.0 5.1 1.2e-11 44.1 0.1 4.2 3 1 0 4 4 4 2 Protein of unknown function (DUF3719) BTB PF00651.31 PVD37576.1 - 2.6e-19 69.5 1.0 5.9e-14 52.2 0.1 3.8 2 2 1 3 3 3 2 BTB/POZ domain HBS1_N PF08938.10 PVD37576.1 - 1.5e-05 25.2 0.0 4.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 HBS1 N-terminus Ufd2P_core PF10408.9 PVD37577.1 - 1.4e-164 549.2 7.4 1.7e-164 548.9 7.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 PVD37577.1 - 4.7e-29 100.4 0.8 1.1e-28 99.1 0.8 1.7 1 0 0 1 1 1 1 U-box domain SKA2 PF16740.5 PVD37577.1 - 7.6 6.4 7.5 0.8 9.5 1.8 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Lig_chan-Glu_bd PF10613.9 PVD37578.1 - 9.6e-29 99.9 0.0 1.7e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD37578.1 - 4.1e-23 81.9 1.1 4.1e-23 81.9 1.1 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD37578.1 - 9.4e-19 67.7 0.0 1.6e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Shisa PF13908.6 PVD37578.1 - 0.0029 17.9 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ANF_receptor PF01094.28 PVD37578.1 - 0.0033 16.6 1.3 0.0084 15.2 0.3 1.9 2 0 0 2 2 2 1 Receptor family ligand binding region DUF4834 PF16118.5 PVD37578.1 - 0.018 16.0 0.1 0.04 14.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MLANA PF14991.6 PVD37578.1 - 0.54 10.6 1.7 0.74 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein melan-A ANAPC_CDC26 PF10471.9 PVD37578.1 - 1.9 9.3 4.7 0.57 11.1 1.5 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Lig_chan-Glu_bd PF10613.9 PVD37579.1 - 1.3e-29 102.7 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD37579.1 - 2.6e-22 79.3 0.0 6.1e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD37579.1 - 9.5e-21 74.2 0.0 1.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Shisa PF13908.6 PVD37579.1 - 0.0014 18.9 0.2 0.0023 18.2 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 PVD37579.1 - 0.0091 16.9 0.1 0.022 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) MLANA PF14991.6 PVD37579.1 - 0.1 12.9 1.2 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein melan-A Lig_chan-Glu_bd PF10613.9 PVD37580.1 - 4.2e-32 110.7 0.0 8.2e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 PVD37580.1 - 4.2e-26 91.6 0.3 7.8e-26 90.7 0.3 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD37580.1 - 4.9e-19 68.7 0.0 7.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PVD37581.1 - 2e-30 105.6 0.8 3.8e-30 104.7 0.8 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD37581.1 - 8.8e-14 51.7 0.0 1.5e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD37581.1 - 4.8e-12 45.8 0.0 1.4e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD37581.1 - 2.1e-07 30.4 0.0 3.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 PVD37583.1 - 1.8e-23 83.1 0.2 3.3e-23 82.2 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD37583.1 - 1.2e-21 77.0 0.0 3e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD37583.1 - 4.3e-14 52.5 0.0 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF4118 PF13493.6 PVD37583.1 - 1 9.2 7.7 6.2 6.7 1.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Lig_chan PF00060.26 PVD37584.1 - 3.7e-35 120.9 0.5 6.6e-35 120.1 0.5 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD37584.1 - 4.8e-29 100.9 0.0 1.1e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD37584.1 - 5.1e-19 68.6 0.0 1e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Parvo_coat_N PF08398.10 PVD37584.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Lig_chan PF00060.26 PVD37585.1 - 1.2e-33 116.1 0.2 2.1e-33 115.3 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD37585.1 - 1.3e-27 96.2 0.0 2.5e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD37585.1 - 1.5e-19 70.3 0.0 5.3e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD37585.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 PVD37587.1 - 1.9e-28 99.2 0.7 3.5e-28 98.3 0.7 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD37587.1 - 2.2e-24 85.9 0.0 1.2e-21 77.0 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD37587.1 - 3.1e-20 72.6 0.0 7.5e-14 51.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Bac_export_1 PF01311.20 PVD37587.1 - 0.036 13.6 0.5 0.11 12.1 0.5 1.8 1 0 0 1 1 1 0 Bacterial export proteins, family 1 Cadherin PF00028.17 PVD37589.1 - 1.7e-15 57.2 0.2 6.1e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 Cadherin domain 7tm_1 PF00001.21 PVD37590.1 - 5e-23 81.8 18.3 6.7e-23 81.3 18.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD37590.1 - 1e-09 38.1 19.8 8.7e-09 35.1 19.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD37590.1 - 5e-09 35.9 21.1 6.6e-09 35.5 20.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD37590.1 - 2.4e-06 27.4 22.8 2.4e-06 27.4 22.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD37590.1 - 0.00028 20.7 8.0 0.00028 20.7 8.0 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 PVD37590.1 - 0.02 14.4 19.1 0.012 15.2 15.8 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Orf78 PF06024.12 PVD37590.1 - 0.13 12.6 1.1 11 6.4 0.6 2.8 2 0 0 2 2 2 0 Orf78 (ac78) GSK-3_bind PF05350.12 PVD37591.1 - 0.0018 17.6 1.3 0.0019 17.5 1.3 1.1 1 0 0 1 1 1 1 Glycogen synthase kinase-3 binding Cadherin PF00028.17 PVD37594.1 - 0.073 13.5 0.1 0.98 9.9 0.1 2.8 3 1 0 3 3 3 0 Cadherin domain Capsid-VNN PF11729.8 PVD37595.1 - 0.1 11.6 0.3 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 nodavirus capsid protein Shisa PF13908.6 PVD37596.1 - 0.0012 19.1 0.1 0.0026 18.0 0.1 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 PVD37596.1 - 0.0032 17.4 0.2 0.0032 17.4 0.2 1.8 2 0 0 2 2 1 1 TMEM154 protein family DAG1 PF05454.11 PVD37596.1 - 0.011 15.1 1.0 0.019 14.3 0.3 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1180 PF06679.12 PVD37596.1 - 0.021 15.3 0.5 0.059 13.8 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ECSCR PF15820.5 PVD37596.1 - 0.022 14.6 0.2 0.044 13.6 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 PVD37596.1 - 0.035 14.1 2.2 0.038 14.0 0.1 1.9 2 0 0 2 2 2 0 Protocadherin Tmemb_9 PF05434.11 PVD37596.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 TMEM9 DUF4448 PF14610.6 PVD37596.1 - 0.054 13.3 0.6 0.27 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 PVD37596.1 - 0.066 13.5 0.2 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 PVD37596.1 - 0.067 14.1 0.2 0.067 14.1 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 PVD37596.1 - 0.12 12.2 0.5 4.8 7.0 0.4 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 PVD37596.1 - 0.2 10.5 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless Glycophorin_A PF01102.18 PVD37596.1 - 0.24 11.7 2.6 0.7 10.1 2.1 2.1 1 1 0 1 1 1 0 Glycophorin A DUF4690 PF15756.5 PVD37596.1 - 0.72 10.5 5.0 0.25 12.0 0.5 2.6 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF4834 PF16118.5 PVD37596.1 - 2.8 8.9 7.3 0.79 10.7 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 PVD37596.1 - 2.9 8.6 5.8 0.6 10.7 0.8 2.4 2 1 1 3 3 2 0 Oxaloacetate decarboxylase, gamma chain Collectrin PF16959.5 PVD37596.1 - 4.9 6.9 7.1 17 5.2 7.1 1.8 1 1 0 1 1 1 0 Renal amino acid transporter Dynactin_p62 PF05502.13 PVD37597.1 - 1.1e-27 97.0 24.6 1.3e-15 57.2 1.7 3.8 4 0 0 4 4 4 3 Dynactin p62 family Elf1 PF05129.13 PVD37597.1 - 0.14 12.2 2.0 0.84 9.7 1.2 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF4411 PF14367.6 PVD37597.1 - 0.31 10.9 6.0 1.6 8.7 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4411) ABC_membrane PF00664.23 PVD37598.1 - 3.7e-94 315.4 43.3 1.6e-43 149.3 14.6 4.4 3 1 1 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 PVD37598.1 - 1.4e-32 113.1 1.7 4.4e-13 49.9 0.0 3.6 2 1 1 3 3 3 3 ABC transporter MTABC_N PF16185.5 PVD37598.1 - 3.6e-07 29.9 7.4 3.6e-07 29.9 7.4 3.1 5 0 0 5 5 5 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 PVD37598.1 - 8.5e-05 22.6 1.1 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD37598.1 - 0.00021 21.2 1.1 0.014 15.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 PVD37598.1 - 0.0013 18.0 0.4 0.057 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 PVD37598.1 - 0.0023 17.6 1.7 0.57 10.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PVD37598.1 - 0.004 17.6 0.2 0.96 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 PVD37598.1 - 0.029 13.5 0.1 0.2 10.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 PVD37598.1 - 0.03 14.8 1.0 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 PVD37598.1 - 0.034 13.6 3.7 2.1 7.7 0.2 3.3 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 PVD37598.1 - 0.054 13.6 2.8 6.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 PVD37598.1 - 0.14 12.2 6.9 0.065 13.3 1.3 2.4 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 PVD37598.1 - 0.15 11.6 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PVD37598.1 - 0.18 11.4 2.2 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 PVD37598.1 - 0.22 11.3 0.7 10 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_J PF04911.12 PVD37598.1 - 0.4 10.3 1.4 2.4 7.8 0.1 2.7 2 0 0 2 2 2 0 ATP synthase j chain CPP1-like PF11833.8 PVD37598.1 - 0.7 9.5 11.5 3.8 7.1 6.7 2.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ABC_tran PF00005.27 PVD37599.1 - 2.8e-12 47.3 0.0 4.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD37599.1 - 0.0016 17.9 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PVD37599.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class FYVE PF01363.21 PVD37600.1 - 0.0015 18.6 1.1 0.0015 18.6 1.1 1.8 2 0 0 2 2 2 1 FYVE zinc finger PolC_DP2 PF03833.13 PVD37600.1 - 0.49 8.2 3.1 0.51 8.1 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 PVD37600.1 - 1.1 9.3 13.6 3.5 7.7 13.6 1.8 1 1 0 1 1 1 0 zinc-ribbons Peptidase_M24 PF00557.24 PVD37602.1 - 6.7e-50 169.7 0.2 9.8e-50 169.1 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 PVD37602.1 - 1.3e-20 73.4 9.2 3.7e-20 72.0 9.2 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PVD37602.1 - 0.00088 19.3 6.0 0.0023 18.0 6.0 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 PVD37602.1 - 0.26 11.2 6.0 0.67 9.9 6.0 1.8 1 0 0 1 1 1 0 HIT zinc finger Ank_2 PF12796.7 PVD37603.1 - 3.6e-99 325.5 27.6 7.7e-16 58.5 0.2 9.4 3 2 9 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37603.1 - 8.2e-65 214.4 16.1 7.8e-09 35.9 0.0 12.2 7 4 6 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37603.1 - 1e-53 178.7 14.7 1.1e-08 35.1 0.1 11.3 5 5 6 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 PVD37603.1 - 1e-50 168.0 19.6 6.2e-05 23.3 0.2 15.4 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 PVD37603.1 - 8.5e-50 160.9 10.2 0.00033 20.9 0.0 16.5 17 0 0 17 17 17 10 Ankyrin repeat SOCS_box PF07525.16 PVD37603.1 - 7.7e-06 26.2 0.7 7.7e-06 26.2 0.7 2.0 2 0 0 2 2 2 1 SOCS box ADH_zinc_N PF00107.26 PVD37604.1 - 1.2e-22 80.3 0.1 1.9e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD37604.1 - 1.2e-22 79.8 2.1 2.6e-22 78.8 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PVD37604.1 - 0.006 17.6 0.0 0.012 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD37604.1 - 0.05 13.1 0.0 0.3 10.5 0.0 2.1 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 PVD37604.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 PVD37604.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain bZIP_1 PF00170.21 PVD37605.1 - 1.6e-09 37.7 13.3 2.6e-09 37.0 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD37605.1 - 5.7e-06 26.3 14.4 9.6e-06 25.6 14.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD37605.1 - 0.0015 19.0 5.5 0.0033 17.9 5.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 PVD37605.1 - 0.24 10.8 4.5 0.36 10.2 4.5 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Med21 PF11221.8 PVD37605.1 - 3.7 7.8 11.2 1.9 8.7 6.2 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex zf-TRAF PF02176.18 PVD37606.1 - 9e-18 64.7 23.1 1.7e-10 41.5 1.8 2.9 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 PVD37606.1 - 4.2e-09 36.1 3.7 4.2e-09 36.1 3.7 3.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD37606.1 - 1.7e-08 34.1 2.3 1.7e-08 34.1 2.3 3.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD37606.1 - 3.6e-07 30.1 3.3 3.6e-07 30.1 3.3 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD37606.1 - 2.4e-06 27.6 2.7 2.4e-06 27.6 2.7 3.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PVD37606.1 - 2.4e-06 27.8 3.9 2.4e-06 27.8 3.9 4.2 3 1 3 6 6 6 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD37606.1 - 3.8e-05 23.5 3.6 3.8e-05 23.5 3.6 4.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 PVD37606.1 - 0.00027 20.7 0.7 0.00027 20.7 0.7 3.0 3 1 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-TRAF_2 PF15965.5 PVD37606.1 - 0.94 10.0 25.2 1.2 9.7 11.3 4.0 1 1 4 5 5 5 0 TRAF-like zinc-finger WD40 PF00400.32 PVD37607.1 - 1e-16 61.0 11.3 0.00015 22.5 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 PVD37607.1 - 0.001 17.8 0.1 1.1 7.8 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PVD37607.1 - 0.0019 18.5 0.0 38 4.7 0.0 5.0 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 PVD37607.1 - 0.002 18.0 1.2 0.0031 17.3 0.2 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PVD37607.1 - 0.0081 16.0 0.4 0.024 14.5 0.4 1.8 1 0 0 1 1 1 1 F-box-like AAA_6 PF12774.7 PVD37608.1 - 0 1062.2 0.0 1e-159 530.8 0.0 4.6 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD37608.1 - 8.3e-291 963.6 33.1 5.8e-150 499.8 10.8 4.1 3 0 0 3 3 2 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD37608.1 - 9.7e-207 683.9 9.7 3e-105 351.2 0.4 3.1 3 0 0 3 3 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD37608.1 - 5.8e-181 597.8 21.4 1e-91 306.0 4.4 3.9 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 PVD37608.1 - 5e-158 521.4 2.1 5e-77 257.5 0.0 6.0 6 0 0 6 6 6 2 P-loop containing dynein motor region Dynein_C PF18199.1 PVD37608.1 - 4e-135 449.9 0.0 2.8e-88 296.1 0.0 3.5 3 0 0 3 3 2 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 PVD37608.1 - 4.7e-125 413.5 0.0 1.1e-61 207.4 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD37608.1 - 2.2e-95 314.9 0.0 9.2e-44 148.4 0.0 5.4 4 0 0 4 4 4 3 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD37608.1 - 2.4e-91 306.3 26.3 8.5e-47 159.8 9.6 2.6 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PVD37608.1 - 4e-65 217.7 11.0 1.8e-34 118.6 0.4 3.9 4 0 0 4 4 3 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD37608.1 - 9.1e-42 142.3 0.0 8.8e-08 32.2 0.0 11.7 10 2 0 10 10 10 6 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PVD37608.1 - 2.1e-39 133.7 2.6 6.9e-19 67.9 0.2 4.3 4 0 0 4 4 2 2 AAA+ lid domain AAA PF00004.29 PVD37608.1 - 2.8e-13 50.5 0.1 0.48 10.8 0.0 7.3 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PVD37608.1 - 9.4e-11 42.1 0.7 0.55 10.5 0.0 8.0 8 0 0 8 8 8 2 AAA domain RNA_helicase PF00910.22 PVD37608.1 - 3e-10 40.5 0.3 1.6 9.2 0.0 7.1 6 0 0 6 6 5 3 RNA helicase AAA_16 PF13191.6 PVD37608.1 - 4.3e-09 37.0 0.0 0.28 11.6 0.0 5.4 5 0 0 5 5 4 2 AAA ATPase domain T2SSE PF00437.20 PVD37608.1 - 1.4e-08 34.2 0.0 0.0027 16.8 0.0 3.1 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.6 PVD37608.1 - 1.7e-05 25.3 6.4 2.6 8.6 0.0 7.5 7 0 0 7 7 6 1 AAA domain Sigma54_activat PF00158.26 PVD37608.1 - 6.3e-05 22.7 0.2 0.27 10.9 0.0 3.9 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_30 PF13604.6 PVD37608.1 - 0.0001 22.1 1.3 5.6 6.6 0.1 4.5 4 0 0 4 4 4 0 AAA domain PhoH PF02562.16 PVD37608.1 - 0.0005 19.6 2.4 2.1 7.8 0.0 4.2 4 0 0 4 4 4 2 PhoH-like protein RsgA_GTPase PF03193.16 PVD37608.1 - 0.0029 17.5 0.0 1.5 8.7 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 PVD37608.1 - 0.0044 16.4 0.3 58 3.0 0.1 5.2 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 PVD37608.1 - 0.011 15.3 1.2 8.3 5.9 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 PVD37608.1 - 0.012 15.8 0.1 34 4.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 PVD37608.1 - 0.013 15.2 0.7 45 3.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 PVD37608.1 - 0.025 14.3 0.0 12 5.7 0.0 3.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pigment_DH PF06324.11 PVD37608.1 - 0.026 14.6 0.8 15 5.9 0.1 3.4 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) IstB_IS21 PF01695.17 PVD37608.1 - 0.038 13.7 0.0 7.7 6.2 0.0 3.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Guanylate_kin PF00625.21 PVD37608.1 - 0.04 13.6 0.0 3 7.5 0.0 3.2 2 0 0 2 2 2 0 Guanylate kinase ubiquitin PF00240.23 PVD37608.1 - 0.74 9.6 3.0 24 4.8 0.0 4.3 5 0 0 5 5 2 0 Ubiquitin family Sun2_CC2 PF18580.1 PVD37608.1 - 1.3 9.3 7.3 7.9 6.8 0.6 3.0 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Cytidylate_kin PF02224.18 PVD37608.1 - 1.4 8.6 4.1 25 4.5 0.1 4.1 5 0 0 5 5 4 0 Cytidylate kinase ABC_tran PF00005.27 PVD37608.1 - 1.9 9.0 6.1 45 4.5 0.0 5.2 5 0 0 5 5 4 0 ABC transporter QVR PF17064.5 PVD37609.1 - 0.011 16.0 1.6 0.014 15.6 1.6 1.2 1 0 0 1 1 1 0 Sleepless protein SCRG1 PF15224.6 PVD37609.1 - 0.043 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Scrapie-responsive protein 1 QVR PF17064.5 PVD37610.1 - 4.4e-14 52.5 20.7 1e-07 32.1 6.4 2.2 2 0 0 2 2 2 2 Sleepless protein zf-tcix PF14952.6 PVD37610.1 - 0.00032 20.2 0.0 0.085 12.5 0.0 2.9 2 0 0 2 2 2 1 Putative treble-clef, zinc-finger, Zn-binding UPAR_LY6 PF00021.21 PVD37610.1 - 0.00054 20.6 21.2 0.01 16.5 6.1 2.5 2 0 0 2 2 2 2 u-PAR/Ly-6 domain APAF1_C PF17908.1 PVD37610.1 - 0.01 15.9 0.6 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 APAF-1 helical domain Fungal_trans_2 PF11951.8 PVD37610.1 - 0.057 12.2 5.5 0.84 8.4 0.3 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain CxC2 PF18803.1 PVD37610.1 - 0.32 11.2 4.2 12 6.2 0.1 2.6 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases Perm-CXXC PF15629.6 PVD37610.1 - 0.51 10.7 5.3 19 5.6 0.1 3.2 2 0 0 2 2 2 0 Permuted single zf-CXXC unit DinI PF06183.13 PVD37610.1 - 1.6 9.1 9.9 1.4 9.3 1.4 2.7 2 0 0 2 2 2 0 DinI-like family Ogr_Delta PF04606.12 PVD37610.1 - 7.3 6.7 14.7 1.4 9.0 0.7 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DEAD PF00270.29 PVD37611.1 - 5.2e-48 163.1 0.1 8.5e-48 162.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37611.1 - 3e-30 104.8 0.2 1.6e-28 99.2 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PVD37611.1 - 3.1e-07 29.9 3.0 5e-07 29.2 3.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PVD37611.1 - 5.7e-06 26.4 0.0 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PVD37611.1 - 0.0091 15.7 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PHF5 PF03660.14 PVD37612.1 - 1.1e-40 138.0 11.0 2.5e-40 136.9 11.0 1.5 1 1 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 PVD37612.1 - 0.0088 14.0 3.8 0.0094 13.9 3.8 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 PVD37612.1 - 0.0089 16.3 13.7 0.14 12.5 2.5 2.3 1 1 1 2 2 2 2 C1 domain DZR PF12773.7 PVD37612.1 - 2.7 8.1 12.6 2 8.5 1.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.6 PVD37612.1 - 6.3 6.8 12.2 3.7 7.5 4.9 2.7 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zn-ribbon_14 PF16503.5 PVD37612.1 - 6.4 6.4 11.8 0.34 10.5 1.0 3.1 2 1 1 3 3 3 0 Zinc-ribbon PH PF00169.29 PVD37613.1 - 3.2e-21 75.8 2.4 4.1e-21 75.5 2.4 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD37613.1 - 4e-06 27.2 3.6 0.0002 21.8 3.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PVD37613.1 - 4.7e-06 27.0 2.3 4.1e-05 23.9 1.7 2.3 1 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PVD37613.1 - 0.037 14.1 1.8 0.16 12.1 1.8 1.8 1 1 0 1 1 1 0 PH domain Hid1 PF12722.7 PVD37614.1 - 9e-289 960.2 0.0 1e-288 960.0 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 PVD37614.1 - 7.7e-260 863.7 0.0 8.7e-260 863.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CDC27 PF09507.10 PVD37614.1 - 0.56 9.5 5.6 0.82 9.0 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 IQ PF00612.27 PVD37615.1 - 0.097 12.5 0.4 0.33 10.9 0.4 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Not3 PF04065.15 PVD37616.1 - 7.7e-74 248.0 31.0 1.4e-58 198.0 13.6 2.8 2 1 1 3 3 3 2 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 PVD37616.1 - 1.5e-43 148.0 9.5 5.9e-43 146.1 9.5 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family PI3K_P85_iSH2 PF16454.5 PVD37616.1 - 0.013 15.1 4.4 0.013 15.1 4.4 2.2 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2748 PF10871.8 PVD37616.1 - 2 6.9 6.2 0.35 9.4 1.7 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2748) PH PF00169.29 PVD37617.1 - 1.2e-09 38.6 2.9 1.6e-09 38.2 0.1 2.5 3 0 0 3 3 3 1 PH domain PH_6 PF15406.6 PVD37617.1 - 0.0035 17.6 0.2 0.011 16.0 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DEAD PF00270.29 PVD37618.1 - 1.4e-50 171.5 0.0 9.2e-50 168.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37618.1 - 6.3e-15 55.5 0.1 5.7e-06 26.6 0.1 3.1 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 PVD37618.1 - 3e-05 24.1 0.0 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 PVD37618.1 - 0.13 12.1 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Paf67 PF10255.9 PVD37619.1 - 4.5e-140 467.2 12.0 2.2e-97 326.6 3.8 2.1 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 SapB_2 PF03489.17 PVD37620.1 - 1e-129 422.2 83.0 1.7e-11 44.0 0.8 15.4 14 0 0 14 14 14 14 Saposin-like type B, region 2 SapB_1 PF05184.15 PVD37620.1 - 8e-105 342.1 84.3 2.2e-11 43.6 1.3 14.3 13 0 0 13 13 13 11 Saposin-like type B, region 1 SapA PF02199.15 PVD37620.1 - 2.3e-17 62.9 26.2 6.4e-11 42.4 8.4 4.6 4 0 0 4 4 2 2 Saposin A-type domain CDT1_C PF16679.5 PVD37620.1 - 1.1e-09 38.6 5.8 7 7.2 0.0 8.8 7 1 1 8 8 8 0 DNA replication factor Cdt1 C-terminal domain Utp12 PF04003.12 PVD37620.1 - 1.5e-08 34.9 7.4 4 7.8 0.0 9.8 5 2 4 9 9 9 1 Dip2/Utp12 Family DUF1722 PF08349.11 PVD37620.1 - 3.2e-07 30.7 0.0 0.84 9.9 0.0 7.4 7 1 2 9 9 9 1 Protein of unknown function (DUF1722) DUF4359 PF14271.6 PVD37620.1 - 7.6e-07 29.8 38.5 14 6.5 0.1 13.0 13 1 0 14 14 12 0 Domain of unknown function (DUF4359) ER PF01133.17 PVD37620.1 - 1e-06 28.6 8.4 33 4.6 0.0 8.1 8 0 0 8 8 8 0 Enhancer of rudimentary Tn7_Tnp_TnsA_C PF08721.11 PVD37620.1 - 1.2e-06 29.0 0.1 17 6.1 0.0 7.5 7 0 0 7 7 6 0 TnsA endonuclease C terminal DUF3567 PF12091.8 PVD37620.1 - 1.3e-06 28.4 1.6 63 3.8 0.0 8.0 8 0 0 8 8 8 0 Protein of unknown function (DUF3567) Histidinol_dh PF00815.20 PVD37620.1 - 2.4e-06 26.8 2.2 22 3.9 0.0 7.3 8 0 0 8 8 8 0 Histidinol dehydrogenase ATLF PF07737.11 PVD37620.1 - 4.5e-06 26.1 0.0 18 4.5 0.0 5.7 5 0 0 5 5 5 0 Anthrax toxin lethal factor, N- and C-terminal domain Ribosomal_L34e PF01199.18 PVD37620.1 - 9.9e-06 25.8 12.5 3.9 7.9 0.1 7.5 7 0 0 7 7 7 2 Ribosomal protein L34e DUF3039 PF11238.8 PVD37620.1 - 0.00017 21.3 24.1 12 5.8 0.2 8.2 8 0 0 8 8 8 0 Protein of unknown function (DUF3039) DRIM PF07539.12 PVD37620.1 - 0.0014 17.0 32.2 0.35 9.1 1.0 7.2 2 1 3 5 5 5 4 Down-regulated in metastasis zf-C2H2_6 PF13912.6 PVD37620.1 - 0.0042 17.0 16.6 8.4 6.5 0.2 7.1 6 0 0 6 6 6 0 C2H2-type zinc finger FIVAR PF07554.13 PVD37620.1 - 0.0045 17.7 9.5 1.4e+02 3.3 0.0 7.7 8 0 0 8 8 8 0 FIVAR domain HTH_16 PF12645.7 PVD37620.1 - 0.0054 16.8 0.6 2.1e+02 2.0 0.0 5.7 6 0 0 6 6 5 0 Helix-turn-helix domain Peptidase_M24 PF00557.24 PVD37620.1 - 0.014 15.0 0.0 41 3.8 0.0 4.8 4 1 2 6 6 6 0 Metallopeptidase family M24 DUF2513 PF10711.9 PVD37620.1 - 0.033 14.5 5.0 2.1e+02 2.3 0.0 6.0 6 0 0 6 6 6 0 Hypothetical protein (DUF2513) Anti-adapt_IraP PF10796.9 PVD37620.1 - 0.065 13.8 3.8 3.8 8.1 0.0 5.4 7 0 0 7 7 7 0 Sigma-S stabilisation anti-adaptor protein DENN PF02141.21 PVD37620.1 - 0.088 12.8 5.2 2.5e+02 1.5 0.0 6.6 8 0 0 8 8 8 0 DENN (AEX-3) domain Gasdermin_C PF17708.1 PVD37620.1 - 0.36 10.9 29.1 9.7 6.3 0.1 8.9 9 0 0 9 9 8 0 Gasdermin PUB domain BAR_3 PF16746.5 PVD37620.1 - 0.89 9.2 3.9 9 5.9 0.0 3.8 4 0 0 4 4 3 0 BAR domain of APPL family YtzH PF14165.6 PVD37620.1 - 1.4 9.4 19.2 8 6.9 0.1 8.1 10 0 0 10 10 8 0 YtzH-like protein ParB PF08775.10 PVD37620.1 - 2.3 8.7 4.5 1.6e+02 2.7 0.1 5.2 8 0 0 8 8 5 0 ParB family MerR_1 PF13411.6 PVD37620.1 - 2.8 8.1 6.5 1.8e+02 2.3 0.0 5.5 6 0 0 6 6 6 0 MerR HTH family regulatory protein Sec7_N PF12783.7 PVD37620.1 - 5.9 6.8 9.7 10 6.0 0.0 4.7 6 0 0 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal YL1_C PF08265.11 PVD37621.1 - 0.084 12.7 18.3 1.4e+02 2.4 0.0 8.0 8 0 0 8 8 8 0 YL1 nuclear protein C-terminal domain HTH_31 PF13560.6 PVD37622.1 - 0.043 14.2 0.2 0.3 11.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M35 PF02102.15 PVD37622.1 - 0.057 12.3 0.1 0.078 11.8 0.1 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Neur_chan_LBD PF02931.23 PVD37623.1 - 1.1e-56 191.6 0.0 1.7e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD37623.1 - 7e-37 127.8 1.8 4.5e-34 118.6 2.7 2.5 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tox-ART-HYD1 PF15633.6 PVD37625.1 - 5.5e-08 33.4 0.0 6.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase Tox-ART-HYD1 PF15633.6 PVD37626.1 - 3.7e-09 37.1 0.0 4.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase RabGAP-TBC PF00566.18 PVD37627.1 - 6.3e-47 160.0 1.2 9.5e-47 159.4 1.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 PVD37627.1 - 9.7e-33 113.0 0.2 1.9e-32 112.0 0.2 1.5 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 PVD37627.1 - 9.2e-11 41.2 0.0 1.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PVD37627.1 - 2.1e-10 40.3 0.0 5.2e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD37627.1 - 1.2e-09 37.7 0.0 2.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sulfotransfer_1 PF00685.27 PVD37628.1 - 0.0017 17.9 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PVD37628.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_2 PF03567.14 PVD37628.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family Mito_carr PF00153.27 PVD37630.1 - 3.7e-53 177.4 0.3 2.9e-21 75.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fz PF01392.22 PVD37631.1 - 5.8e-09 36.5 0.1 1e-08 35.8 0.1 1.4 1 0 0 1 1 1 1 Fz domain Caa3_CtaG PF09678.10 PVD37633.1 - 0.61 9.5 15.4 0.11 12.0 8.9 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) PX PF00787.24 PVD37634.1 - 3.4e-20 72.1 0.0 7.2e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF641 PF04859.12 PVD37634.1 - 0.0002 21.7 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) LRRFIP PF09738.9 PVD37634.1 - 0.0065 16.0 0.8 0.013 15.0 0.8 1.4 1 0 0 1 1 1 1 LRRFIP family Tropomyosin_1 PF12718.7 PVD37634.1 - 0.0075 16.4 1.0 0.014 15.6 1.0 1.3 1 0 0 1 1 1 1 Tropomyosin like CENP-F_N PF10481.9 PVD37634.1 - 0.015 15.0 0.4 0.028 14.1 0.4 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain ATG16 PF08614.11 PVD37634.1 - 0.015 15.5 3.7 0.026 14.7 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 PVD37634.1 - 0.075 13.1 1.6 0.12 12.5 1.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding End3 PF12761.7 PVD37634.1 - 0.086 13.0 0.9 0.18 12.0 0.9 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TMF_DNA_bd PF12329.8 PVD37634.1 - 0.093 12.7 2.7 0.17 11.9 2.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tektin PF03148.14 PVD37634.1 - 0.095 11.4 2.0 0.14 10.9 2.0 1.2 1 0 0 1 1 1 0 Tektin family SlyX PF04102.12 PVD37634.1 - 0.22 12.2 1.3 0.66 10.6 1.3 1.8 1 0 0 1 1 1 0 SlyX Rootletin PF15035.6 PVD37634.1 - 0.25 11.3 4.1 0.43 10.6 4.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Pkinase PF00069.25 PVD37635.1 - 7.7e-76 254.9 0.0 8.6e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD37635.1 - 3.2e-35 121.7 0.0 4.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD37635.1 - 6e-06 25.4 0.1 1.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PVD37635.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PVD37635.1 - 0.0056 16.3 0.1 0.0086 15.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family CzcE PF16986.5 PVD37635.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE Kdo PF06293.14 PVD37635.1 - 0.031 13.6 0.2 0.088 12.2 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PVD37635.1 - 0.059 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 PVD37635.1 - 0.084 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Recep_L_domain PF01030.24 PVD37635.1 - 0.17 12.0 0.1 0.52 10.4 0.0 1.7 2 0 0 2 2 2 0 Receptor L domain Choline_kinase PF01633.20 PVD37635.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Raptor_N PF14538.6 PVD37636.1 - 3.8e-69 231.3 0.0 7.2e-69 230.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 PVD37636.1 - 1.2e-13 51.3 6.9 0.0014 19.4 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.22 PVD37636.1 - 1.1e-10 40.9 0.8 0.00025 21.0 0.0 5.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 PVD37636.1 - 2.5e-06 27.8 0.1 4.6e-05 23.7 0.0 3.1 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 PVD37636.1 - 0.00012 22.2 0.0 0.0033 17.5 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 PVD37636.1 - 0.025 14.9 0.0 2.8 8.3 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 PVD37636.1 - 0.034 14.7 0.1 0.24 11.9 0.0 2.5 2 0 0 2 2 2 0 HEAT-like repeat SUFU PF05076.13 PVD37637.1 - 2.3e-39 135.1 0.0 3.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) SUFU_C PF12470.8 PVD37637.1 - 2.9e-23 83.0 0.0 8.8e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain FtsJ PF01728.19 PVD37638.1 - 5.8e-57 192.6 0.0 7.2e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PVD37638.1 - 0.0096 15.7 0.0 0.22 11.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Flavin_Reduct PF01613.18 PVD37639.1 - 2.3e-35 121.9 0.0 4.1e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain SNF2_N PF00176.23 PVD37640.1 - 4.3e-51 173.7 0.0 4.3e-51 173.7 0.0 2.9 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD37640.1 - 5.8e-14 52.4 0.0 3.1e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD37640.1 - 2.3e-05 24.4 0.0 2.3e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Herpes_UL25 PF01499.16 PVD37640.1 - 0.013 14.0 3.8 0.026 13.0 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Syntaxin-6_N PF09177.11 PVD37640.1 - 8.6 7.0 10.8 2.5 8.7 5.9 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Big_4 PF07532.11 PVD37641.1 - 0.048 13.4 0.1 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) TUG-UBL1 PF11470.8 PVD37642.1 - 5e-26 90.7 1.4 1.3e-25 89.4 0.3 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 PVD37642.1 - 4e-16 59.0 0.0 2e-08 34.3 0.0 3.6 3 0 0 3 3 3 3 UBX domain RBD PF02196.15 PVD37642.1 - 0.0048 17.0 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 Raf-like Ras-binding domain UN_NPL4 PF11543.8 PVD37642.1 - 0.0081 16.6 0.0 0.31 11.5 0.0 2.9 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Rad60-SLD PF11976.8 PVD37642.1 - 0.087 12.7 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like C2 PF00168.30 PVD37643.1 - 3.4e-05 24.1 0.1 0.00017 21.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain DUF3584 PF12128.8 PVD37643.1 - 0.27 8.7 31.0 0.38 8.2 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 PVD37643.1 - 2.2 6.7 9.2 1.4 7.3 7.5 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S46 PF10459.9 PVD37643.1 - 4.2 5.9 13.9 5.9 5.4 13.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Pkinase_Tyr PF07714.17 PVD37644.1 - 3.1e-38 131.6 0.0 4.6e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37644.1 - 2.8e-34 118.7 0.0 3.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 PVD37644.1 - 3.5e-12 45.6 0.2 6.1e-12 44.8 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 PVD37644.1 - 3e-06 26.3 0.2 1.9e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase DUF3377 PF11857.8 PVD37644.1 - 0.016 15.1 0.4 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 PVD37644.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 PVD37644.1 - 0.022 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FTA2 PF13095.6 PVD37644.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SCIMP PF15050.6 PVD37644.1 - 0.066 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 SCIMP protein APH PF01636.23 PVD37644.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mid2 PF04478.12 PVD37644.1 - 0.16 11.8 0.6 0.28 11.0 0.6 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor N_methyl PF07963.12 PVD37644.1 - 0.7 9.6 3.2 1.7 8.4 3.2 1.7 1 1 0 1 1 1 0 Prokaryotic N-terminal methylation motif Kinesin PF00225.23 PVD37645.1 - 2.9e-91 305.8 0.9 4.6e-91 305.2 0.9 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PVD37645.1 - 2.9e-23 82.5 0.2 4.8e-22 78.5 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Mvb12 PF09452.10 PVD37645.1 - 0.00042 20.7 1.8 0.015 15.7 0.3 3.0 2 0 0 2 2 2 1 ESCRT-I subunit Mvb12 ADPrib_exo_Tox PF03496.14 PVD37645.1 - 0.038 13.3 1.7 0.077 12.3 0.7 2.0 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme AAA_22 PF13401.6 PVD37645.1 - 0.053 13.8 0.6 0.49 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain TMP-TENI PF02581.17 PVD37645.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase KxDL PF10241.9 PVD37645.1 - 2 8.8 5.7 7.6 6.9 0.7 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DHR10 PF18595.1 PVD37645.1 - 7 6.7 12.6 4.7 7.3 2.2 3.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 PVD37645.1 - 9.4 7.0 9.6 3.5 8.4 0.6 3.6 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Arrestin_C PF02752.22 PVD37646.1 - 2e-05 25.0 0.0 7.2e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PVD37647.1 - 0.00081 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RCC1 PF00415.18 PVD37648.1 - 1e-50 170.1 14.2 7.6e-11 42.5 0.2 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD37648.1 - 6.1e-25 86.4 34.1 1e-08 34.8 3.3 9.0 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 PVD37648.1 - 2.1e-20 71.3 32.3 0.00049 19.8 0.6 9.2 9 1 0 9 9 9 6 MORN repeat VPS9 PF02204.18 PVD37648.1 - 7.2e-14 51.9 2.5 8.5e-14 51.6 0.1 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 PVD37648.1 - 0.0015 19.0 0.0 0.016 15.7 0.1 2.4 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 PVD37648.1 - 0.033 14.4 0.9 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 RhoGEF domain AAA_6 PF12774.7 PVD37649.1 - 1.4e-152 507.4 0.0 4.1e-151 502.6 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD37649.1 - 5.5e-146 486.7 1.3 5.5e-146 486.7 1.3 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD37649.1 - 4.7e-119 397.2 0.0 1.4e-118 395.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD37649.1 - 3.2e-108 361.0 0.8 6.2e-106 353.5 0.3 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD37649.1 - 3.3e-95 317.4 3.1 3.3e-95 317.4 3.1 3.8 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD37649.1 - 2.1e-85 284.8 0.0 1.3e-82 275.7 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD37649.1 - 7.8e-63 211.2 1.1 1.7e-62 210.1 0.1 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PVD37649.1 - 3.6e-49 165.8 0.0 1.3e-45 154.3 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PVD37649.1 - 4.6e-37 127.8 2.3 4.6e-37 127.8 2.3 2.5 3 1 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PVD37649.1 - 1.6e-32 112.3 0.1 2.9e-31 108.2 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD37649.1 - 4.2e-19 68.6 0.5 2.1e-18 66.4 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PVD37649.1 - 5.1e-19 68.6 0.0 4.3e-05 23.5 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD37649.1 - 5.6e-06 26.7 2.9 0.37 11.1 0.0 4.8 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 PVD37649.1 - 1e-05 26.0 3.2 1.4 9.4 0.0 5.0 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) DHR10 PF18595.1 PVD37649.1 - 0.00015 21.8 6.4 0.00015 21.8 6.4 4.4 6 1 0 6 6 4 1 Designed helical repeat protein 10 domain AAA_16 PF13191.6 PVD37649.1 - 0.00085 19.7 0.0 8.6 6.7 0.0 3.9 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 PVD37649.1 - 0.0031 17.9 0.0 7.6 7.0 0.0 3.3 2 0 0 2 2 2 0 RNA helicase EF-hand_1 PF00036.32 PVD37649.1 - 0.012 15.1 0.7 0.069 12.7 0.1 2.7 2 0 0 2 2 1 0 EF hand DUF4349 PF14257.6 PVD37649.1 - 0.019 14.4 0.7 0.05 13.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) EF-hand_6 PF13405.6 PVD37649.1 - 0.019 14.9 0.2 0.093 12.7 0.2 2.3 1 0 0 1 1 1 0 EF-hand domain AAA_18 PF13238.6 PVD37649.1 - 0.022 15.3 5.7 0.22 12.1 0.0 5.0 6 0 0 6 6 4 0 AAA domain Sigma54_activat PF00158.26 PVD37649.1 - 0.059 13.1 0.1 0.64 9.7 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain RHSP PF07999.11 PVD37649.1 - 0.07 11.9 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon hot spot protein AAA_30 PF13604.6 PVD37649.1 - 0.14 11.9 0.0 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PVD37649.1 - 0.18 10.9 1.9 0.56 9.2 0.0 2.7 4 0 0 4 4 4 0 Type II/IV secretion system protein EF-hand_7 PF13499.6 PVD37649.1 - 0.23 11.9 3.2 0.58 10.6 1.1 2.9 2 0 0 2 2 1 0 EF-hand domain pair FA_desaturase PF00487.24 PVD37650.1 - 2.7e-31 109.3 23.2 5.6e-22 78.8 4.3 2.7 1 1 2 3 3 3 2 Fatty acid desaturase Cyt-b5 PF00173.28 PVD37650.1 - 5.6e-19 68.1 0.1 9.8e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HHH_3 PF12836.7 PVD37651.1 - 2e-12 47.2 0.1 1.6e-11 44.3 0.0 2.2 1 1 1 2 2 2 1 Helix-hairpin-helix motif Actin PF00022.19 PVD37652.1 - 2.1e-64 217.7 0.0 2.3e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Actin Ank_2 PF12796.7 PVD37653.1 - 1.2e-05 25.8 0.0 0.00023 21.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37653.1 - 4.4e-05 23.9 0.0 0.00023 21.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37653.1 - 0.00012 22.3 0.2 0.66 10.4 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37653.1 - 0.032 14.8 0.0 16 6.4 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat PKD_channel PF08016.12 PVD37653.1 - 0.077 11.7 8.5 0.02 13.6 5.2 1.7 1 1 1 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 PVD37653.1 - 0.1 11.8 24.3 0.51 9.5 24.3 2.0 1 1 0 1 1 1 0 Ion transport protein Actin PF00022.19 PVD37654.1 - 7.8e-151 502.3 0.0 2.4e-150 500.7 0.0 1.6 1 1 0 1 1 1 1 Actin tRNA_bind PF01588.20 PVD37654.1 - 0.11 12.6 0.0 6.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Putative tRNA binding domain Kinesin PF00225.23 PVD37655.1 - 1.3e-84 284.0 7.5 1.3e-69 234.7 1.1 2.4 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 PVD37655.1 - 4.2e-09 36.5 0.2 1.8e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3496 PF12001.8 PVD37655.1 - 0.035 14.5 6.1 2 8.8 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) HR1 PF02185.16 PVD37655.1 - 0.19 11.8 4.3 2.9 8.0 0.9 3.1 2 0 0 2 2 2 0 Hr1 repeat ResIII PF04851.15 PVD37655.1 - 0.45 10.5 7.1 4.7 7.2 0.1 3.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DAGK_cat PF00781.24 PVD37656.1 - 6.5e-27 93.6 0.0 9.8e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Caskin-tail PF16632.5 PVD37657.1 - 2.8e-06 27.6 0.4 1e-05 25.8 0.4 2.0 1 0 0 1 1 1 1 C-terminal region of Caskin Ank_2 PF12796.7 PVD37658.1 - 5.9e-38 129.3 3.6 3e-13 50.1 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37658.1 - 3.7e-34 116.7 3.7 2.8e-08 34.1 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37658.1 - 5.1e-34 115.9 6.3 6.3e-11 42.3 0.2 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD37658.1 - 5.5e-33 112.0 11.5 2.8e-07 30.7 1.5 6.6 5 1 1 6 6 6 5 Ankyrin repeat SAM_1 PF00536.30 PVD37658.1 - 7.6e-32 109.6 0.4 6.7e-17 61.7 0.7 2.5 1 1 1 2 2 2 2 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 PVD37658.1 - 1.1e-30 102.2 4.1 3.1e-06 27.1 0.2 6.0 6 0 0 6 6 5 5 Ankyrin repeat SAM_2 PF07647.17 PVD37658.1 - 5.1e-24 84.2 0.4 1.9e-11 43.9 0.4 2.6 1 1 1 2 2 2 2 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 PVD37658.1 - 2.6e-09 36.6 0.0 1.2e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 PVD37658.1 - 0.00033 20.5 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD37658.1 - 0.00049 19.7 0.0 0.00096 18.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NCD1 PF04904.13 PVD37658.1 - 0.0029 17.5 0.1 1.8 8.6 0.1 2.5 1 1 1 2 2 2 2 NAB conserved region 1 (NCD1) VWC PF00093.18 PVD37663.1 - 0.017 15.4 4.9 2.7 8.4 1.6 3.0 2 1 0 2 2 2 0 von Willebrand factor type C domain SVWC PF15430.6 PVD37663.1 - 0.14 12.4 6.6 5.9 7.2 0.2 3.2 2 1 1 3 3 3 0 Single domain von Willebrand factor type C RVT_1 PF00078.27 PVD37664.1 - 8e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_a PF00057.18 PVD37665.1 - 0.025 14.8 1.7 0.081 13.1 1.7 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A RACo_linker PF17650.1 PVD37665.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RACo linker region DUF5075 PF16825.5 PVD37665.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 IGP family C-type lectin domain adh_short PF00106.25 PVD37667.1 - 7.1e-06 25.6 0.0 8.1e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD37667.1 - 7.3e-05 22.4 0.0 8.2e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD37668.1 - 8.4e-06 25.4 0.1 1.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD37668.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD37669.1 - 2.3e-06 27.2 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD37669.1 - 0.0045 16.6 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 PVD37669.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PrgI PF12666.7 PVD37669.1 - 0.18 12.5 5.1 0.26 12.0 5.1 1.5 1 1 0 1 1 1 0 PrgI family protein 7tm_1 PF00001.21 PVD37670.1 - 5.2e-22 78.4 2.7 8.7e-22 77.7 2.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD37670.1 - 7.8e-05 22.2 1.3 0.00012 21.5 1.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD37670.1 - 0.00079 19.2 2.9 0.0012 18.7 2.9 1.1 1 0 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 PVD37670.1 - 0.0046 16.8 2.1 0.0076 16.0 2.1 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 LRR_6 PF13516.6 PVD37671.1 - 0.00026 20.8 1.9 0.99 9.6 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat polyprenyl_synt PF00348.17 PVD37672.1 - 6.8e-64 215.4 0.3 8.8e-64 215.0 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF948 PF06103.11 PVD37672.1 - 0.074 13.3 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SPRY PF00622.28 PVD37673.1 - 5.2e-13 49.2 0.2 1.2e-05 25.4 0.1 2.5 2 0 0 2 2 2 2 SPRY domain PHD PF00628.29 PVD37673.1 - 0.02 14.8 13.2 0.04 13.8 13.2 1.5 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 PVD37674.1 - 4.2e-05 23.0 2.5 0.012 15.0 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain MAT1 PF06391.13 PVD37674.1 - 0.48 10.2 7.8 0.99 9.2 7.8 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Macoilin PF09726.9 PVD37674.1 - 6 5.3 12.4 0.52 8.8 4.5 2.3 2 0 0 2 2 2 0 Macoilin family HlyIII PF03006.20 PVD37675.1 - 3.8e-31 108.6 19.2 4.8e-31 108.2 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related UNC-93 PF05978.16 PVD37676.1 - 0.0012 18.6 0.3 0.0028 17.4 0.3 1.7 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF35_N PF12172.8 PVD37676.1 - 0.089 12.7 1.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) UNC-93 PF05978.16 PVD37677.1 - 7.5e-08 32.2 6.0 7.5e-08 32.2 6.0 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 BcsB PF03170.13 PVD37677.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Cadherin_tail PF15974.5 PVD37680.1 - 0.083 13.2 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region BAH PF01426.18 PVD37681.1 - 3.8e-12 46.1 0.0 8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain Tudor_3 PF18115.1 PVD37681.1 - 2.1e-06 27.4 0.0 5.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain AAA_16 PF13191.6 PVD37682.1 - 8e-07 29.6 1.2 4.8e-06 27.1 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PVD37682.1 - 4.9e-05 23.6 0.0 0.00017 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PVD37682.1 - 0.0019 18.2 0.0 0.0061 16.5 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 PVD37682.1 - 0.029 14.8 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PVD37682.1 - 0.061 13.2 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea QueF PF14489.6 PVD37682.1 - 0.14 12.4 0.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 QueF-like protein DDHD PF02862.17 PVD37683.1 - 0.09 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 DDHD domain SH3_6 PF12913.7 PVD37683.1 - 0.13 11.9 0.1 0.64 9.6 0.1 2.2 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) Med19 PF10278.9 PVD37683.1 - 0.13 12.2 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Galactosyl_T PF01762.21 PVD37685.1 - 4.6e-37 127.7 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD37685.1 - 0.028 13.8 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Fringe-like Ank_2 PF12796.7 PVD37687.1 - 8.8e-27 93.5 0.2 3.5e-09 37.1 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD37687.1 - 3.1e-20 71.6 7.5 0.00018 21.8 0.0 7.5 7 1 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 PVD37687.1 - 4.4e-17 60.4 6.0 1.7e-05 24.8 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 PVD37687.1 - 5e-17 62.0 1.0 0.00022 21.7 0.0 5.7 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37687.1 - 7.1e-13 48.5 0.2 0.0003 21.0 0.0 4.9 4 2 0 4 4 4 3 Ankyrin repeats (many copies) TIR_2 PF13676.6 PVD37688.1 - 1.2e-09 38.8 0.0 2.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD37688.1 - 1.1e-07 31.8 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 PVD37688.1 - 0.00026 21.0 0.0 0.001 19.1 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD37688.1 - 0.0012 19.4 0.0 0.0053 17.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain DUF4062 PF13271.6 PVD37688.1 - 0.0022 18.3 0.0 1.7 9.0 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4062) TIR_2 PF13676.6 PVD37689.1 - 7.1e-05 23.4 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD37689.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 TIR domain Galactosyl_T PF01762.21 PVD37690.1 - 2.3e-39 135.3 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD37690.1 - 0.012 15.1 0.7 0.027 13.9 0.0 2.0 3 0 0 3 3 3 0 Fringe-like DUF3671 PF12420.8 PVD37690.1 - 0.032 14.3 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function Galactosyl_T PF01762.21 PVD37691.1 - 2.6e-82 275.4 0.0 2.9e-40 138.2 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 PVD37691.1 - 2.3e-07 30.5 0.1 0.0085 15.6 0.0 2.7 2 1 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 PVD37692.1 - 8.7e-42 143.1 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD37692.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Fringe-like DnaJ_C PF01556.18 PVD37693.1 - 8.9e-35 120.0 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PVD37693.1 - 3.8e-27 94.2 1.8 8.1e-27 93.1 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain MEF2_binding PF09047.10 PVD37693.1 - 0.13 12.2 0.3 0.34 10.8 0.3 1.7 1 0 0 1 1 1 0 MEF2 binding Reprolysin_2 PF13574.6 PVD37695.1 - 7.8e-27 94.4 0.3 1.8e-26 93.3 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD37695.1 - 2.1e-23 83.5 1.7 5e-23 82.3 1.7 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 PVD37695.1 - 5.6e-08 33.1 0.4 1.1e-07 32.2 0.4 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM17_MPD PF16698.5 PVD37695.1 - 7.6e-08 32.6 13.4 7.6e-08 32.6 13.4 3.3 3 1 1 4 4 4 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_3 PF13582.6 PVD37695.1 - 4.6e-07 30.4 0.1 9.4e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PVD37695.1 - 0.0003 20.7 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD37695.1 - 0.0017 18.0 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TMEM119 PF15724.5 PVD37695.1 - 0.17 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 TMEM119 family Disintegrin PF00200.23 PVD37695.1 - 0.45 11.3 20.5 0.25 12.2 16.1 2.6 1 1 1 2 2 2 0 Disintegrin CCDC14 PF15254.6 PVD37696.1 - 1.2e-36 126.8 30.4 5e-35 121.5 19.6 3.5 4 1 0 4 4 4 2 Coiled-coil domain-containing protein 14 SlyX PF04102.12 PVD37696.1 - 0.0064 17.1 4.3 0.0064 17.1 4.3 4.9 3 1 0 4 4 4 2 SlyX EzrA PF06160.12 PVD37696.1 - 0.0089 14.3 11.5 0.015 13.5 11.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CCDC92 PF14916.6 PVD37696.1 - 1 9.2 14.2 0.033 14.0 0.7 3.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF4407 PF14362.6 PVD37696.1 - 1.4 8.2 4.2 3.5 6.9 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 PVD37696.1 - 1.4 8.9 25.9 2.4 8.2 5.1 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 PVD37696.1 - 9.2 5.6 25.5 0.72 9.2 3.0 3.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FYVE_2 PF02318.16 PVD37697.1 - 7.6e-32 110.0 17.7 1.3e-31 109.3 17.7 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 PVD37697.1 - 0.0032 17.6 23.7 0.007 16.5 23.7 1.8 1 1 0 1 1 1 1 FYVE zinc finger RGP PF03214.13 PVD37697.1 - 0.0097 15.1 0.5 0.012 14.8 0.5 1.2 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide PolC_DP2 PF03833.13 PVD37699.1 - 0.017 13.1 0.4 0.027 12.3 0.3 1.4 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DDE_Tnp_1_6 PF13751.6 PVD37699.1 - 0.04 14.1 2.7 0.075 13.3 2.7 1.5 1 0 0 1 1 1 0 Transposase DDE domain I-set PF07679.16 PVD37701.1 - 7.7e-40 134.9 0.1 1.4e-21 76.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD37701.1 - 3.2e-27 95.0 0.0 8.3e-13 48.7 0.0 3.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD37701.1 - 3.2e-16 59.4 0.0 5.7e-08 33.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 PVD37701.1 - 4.5e-14 52.4 0.0 9.3e-08 32.1 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD37701.1 - 1.4e-07 31.7 1.7 0.053 13.7 0.1 4.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD37701.1 - 5.5e-07 29.6 0.0 0.0029 17.7 0.0 3.1 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 PVD37701.1 - 0.0045 16.8 0.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 FANCD2OS PF15124.6 PVD37701.1 - 0.074 13.3 0.1 0.31 11.2 0.1 2.1 1 0 0 1 1 1 0 FANCD2 opposite strand protein 7tm_1 PF00001.21 PVD37702.1 - 1.6e-10 40.8 3.7 2.3e-10 40.3 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC_tran PF00005.27 PVD37703.1 - 4.2e-10 40.3 0.9 7.7e-10 39.4 0.1 1.8 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 PVD37703.1 - 1.8e-05 24.7 0.4 2.7e-05 24.2 0.4 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PVD37703.1 - 0.00088 19.3 0.4 0.0014 18.7 0.4 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 PVD37703.1 - 0.0012 18.5 0.2 0.0026 17.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 PVD37703.1 - 0.02 15.0 1.1 0.044 13.9 0.4 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 PVD37703.1 - 0.022 14.8 0.2 0.04 14.0 0.2 1.4 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 PVD37703.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD37703.1 - 0.054 13.9 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PVD37703.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 PVD37703.1 - 0.069 11.9 0.4 0.095 11.5 0.4 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 PVD37703.1 - 0.13 12.8 0.0 0.36 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 PVD37703.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Zeta_toxin PF06414.12 PVD37703.1 - 0.14 11.5 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 PVD37703.1 - 0.16 12.2 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 PVD37703.1 - 0.16 11.2 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 PVD37703.1 - 0.17 12.4 0.8 0.29 11.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PVD37703.1 - 0.2 11.2 0.3 0.3 10.7 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.24 PVD37704.1 - 1.5e-25 89.8 19.4 1.7e-25 89.7 13.1 2.2 1 1 1 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.7 PVD37704.1 - 0.00023 20.4 10.8 0.00042 19.5 10.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein PIP49_N PF14875.6 PVD37704.1 - 0.052 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 ABC_tran PF00005.27 PVD37704.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 PVD37705.1 - 1.2e-12 48.5 0.0 3.9e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Mucin-like PF16058.5 PVD37705.1 - 2.7e-05 24.2 16.8 0.0029 17.6 8.3 2.4 1 1 1 2 2 2 2 Mucin-like AAA_21 PF13304.6 PVD37705.1 - 0.13 12.0 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PVD37705.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 ABC-2 type transporter ABC2_membrane PF01061.24 PVD37706.1 - 2.5e-14 53.2 8.7 3.2e-14 52.9 8.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 PVD37706.1 - 0.00058 19.1 3.9 0.00071 18.8 3.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 PVD37706.1 - 0.044 13.1 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3392 PF11872.8 PVD37706.1 - 0.095 13.0 1.3 0.19 12.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) ABC2_membrane PF01061.24 PVD37707.1 - 2.1e-36 125.3 20.7 3.5e-36 124.6 20.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD37707.1 - 1.6e-17 64.3 0.0 3.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PVD37707.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 PVD37708.1 - 8.4e-34 116.8 19.9 1.3e-33 116.2 19.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD37708.1 - 1.4e-23 84.0 0.1 2.4e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PVD37708.1 - 4.5e-06 26.7 0.1 8.9e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PVD37708.1 - 6.1e-05 22.6 0.8 0.0003 20.3 0.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PVD37708.1 - 0.00031 20.8 0.0 0.00069 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PVD37708.1 - 0.0011 19.3 0.0 0.0077 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PVD37708.1 - 0.0024 18.3 0.0 0.0058 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 PVD37708.1 - 0.0026 17.6 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 PVD37708.1 - 0.0027 17.9 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PVD37708.1 - 0.005 16.6 0.2 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 PVD37708.1 - 0.0073 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain Septin PF00735.18 PVD37708.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_25 PF13481.6 PVD37708.1 - 0.0089 15.6 0.1 0.044 13.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 PVD37708.1 - 0.029 14.8 0.1 0.26 11.7 0.0 2.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 PVD37708.1 - 0.041 14.4 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PVD37708.1 - 0.042 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 PVD37708.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 PVD37708.1 - 0.068 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PVD37708.1 - 0.075 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 PVD37708.1 - 0.077 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 PVD37708.1 - 0.1 13.0 0.4 0.27 11.7 0.1 1.9 2 0 0 2 2 1 0 AAA domain PRK PF00485.18 PVD37708.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Guanylate_kin PF00625.21 PVD37709.1 - 2.4e-48 164.2 0.2 1e-47 162.2 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 PVD37709.1 - 1.1e-21 76.6 5.6 1.1e-21 76.6 5.6 2.3 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal WD40 PF00400.32 PVD37710.1 - 7e-18 64.7 18.0 9.2e-07 29.5 0.7 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD37710.1 - 3.9e-15 55.9 2.0 0.00012 22.3 0.2 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PVD37710.1 - 1.3e-07 31.3 0.0 3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 PVD37710.1 - 0.001 19.0 0.0 0.36 10.7 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 PVD37710.1 - 0.0017 18.1 0.5 10 5.8 0.1 4.0 4 0 0 4 4 4 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 PVD37710.1 - 0.0041 16.1 0.1 0.49 9.3 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PVD37710.1 - 0.029 13.0 0.4 1.9 7.0 0.0 3.0 2 2 2 4 4 4 0 Nucleoporin Nup120/160 SpaA PF17802.1 PVD37711.1 - 0.0037 17.6 15.0 1.5 9.2 0.6 3.8 1 1 2 3 3 3 3 Prealbumin-like fold domain GramPos_pilinD1 PF16555.5 PVD37711.1 - 0.77 9.9 11.3 14 5.8 2.0 3.1 1 1 2 3 3 3 0 Gram-positive pilin subunit D1, N-terminal domain DUF4278 PF14105.6 PVD37711.1 - 2.6 8.6 9.2 69 4.0 9.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) 7tm_1 PF00001.21 PVD37712.1 - 4.5e-06 26.2 7.3 0.00014 21.3 3.5 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 PVD37712.1 - 0.0083 15.7 2.0 0.015 14.8 2.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc IBR PF01485.21 PVD37713.1 - 8.8e-20 70.7 24.2 1.1e-12 47.9 1.5 5.3 5 1 1 6 6 5 2 IBR domain, a half RING-finger domain Ank_4 PF13637.6 PVD37713.1 - 2.2e-07 31.3 0.2 2.3e-05 24.9 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD37713.1 - 0.00016 22.2 0.0 0.0016 19.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) zf-RING_UBOX PF13445.6 PVD37713.1 - 0.00017 21.6 34.0 0.00021 21.2 5.7 3.9 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD37713.1 - 0.00017 21.4 5.2 0.00017 21.4 5.2 4.8 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD37713.1 - 0.00022 21.5 9.1 0.00022 21.5 9.1 5.0 4 1 1 5 5 4 2 Ring finger domain zf-C3HC4 PF00097.25 PVD37713.1 - 0.0012 18.7 9.3 0.0012 18.7 9.3 4.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 PVD37713.1 - 0.0027 18.1 0.0 0.18 12.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat zf-RING_5 PF14634.6 PVD37713.1 - 0.0037 17.2 9.0 0.0037 17.2 9.0 4.3 5 0 0 5 5 3 1 zinc-RING finger domain Ank_3 PF13606.6 PVD37713.1 - 0.0061 17.0 0.0 0.52 11.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Matrilin_ccoil PF10393.9 PVD37713.1 - 0.0091 15.8 0.0 0.032 14.1 0.0 2.0 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Ank_5 PF13857.6 PVD37713.1 - 0.021 15.1 0.0 0.8 10.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) UIM PF02809.20 PVD37713.1 - 0.043 13.7 9.4 0.047 13.6 0.7 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif PCRF PF03462.18 PVD37713.1 - 9.1 6.1 8.3 2.3 8.1 4.1 2.1 2 0 0 2 2 2 0 PCRF domain UCH PF00443.29 PVD37714.1 - 7.8e-42 143.5 21.5 5.3e-41 140.8 21.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PVD37714.1 - 0.015 15.1 1.9 0.015 15.1 1.9 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Peptidase_C98 PF15499.6 PVD37714.1 - 0.35 10.3 5.6 5.3 6.4 1.2 3.6 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cyclin_N PF00134.23 PVD37715.1 - 1.6e-14 53.7 0.1 3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 PVD37715.1 - 5.6e-10 39.8 0.1 7.7e-10 39.4 0.1 1.4 1 1 0 1 1 1 1 Cyclin PPI_Ypi1 PF07491.11 PVD37715.1 - 0.089 12.6 0.5 0.19 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor FA_desaturase PF00487.24 PVD37716.1 - 5.9e-38 131.1 25.4 5.9e-38 131.1 25.4 1.8 3 0 0 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 PVD37716.1 - 8.8e-21 73.8 0.1 1.5e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2101 PF09874.9 PVD37716.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) LST1 PF05083.13 PVD37718.1 - 0.0051 17.1 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 LST-1 protein EphA2_TM PF14575.6 PVD37718.1 - 0.014 16.2 0.0 0.056 14.3 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FGFR3_TM PF18123.1 PVD37718.1 - 1.4 8.5 5.5 3 7.4 5.5 1.6 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain SLR1-BP PF07333.12 PVD37718.1 - 3.8 8.0 13.3 8.4 6.9 13.3 1.6 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF1700 PF08006.11 PVD37718.1 - 9.5 5.7 6.2 8.3 5.9 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) LST1 PF05083.13 PVD37719.1 - 0.0014 18.8 0.5 0.0026 18.0 0.5 1.4 1 0 0 1 1 1 1 LST-1 protein Adeno_E3_CR2 PF02439.15 PVD37719.1 - 0.0028 17.4 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PVD37719.1 - 0.015 16.1 0.0 0.023 15.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD37719.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Trp_oprn_chp PF09534.10 PVD37719.1 - 0.061 13.1 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LSR PF05624.14 PVD37719.1 - 3.9 7.6 5.7 1.3 9.1 1.3 2.0 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) MgtE_N PF03448.17 PVD37720.1 - 2.3e-82 272.2 33.7 9.5e-10 39.0 0.2 15.1 3 2 12 16 16 16 13 MgtE intracellular N domain CDC37_C PF08564.10 PVD37720.1 - 1.2e-07 31.7 112.8 2.1 8.5 0.2 24.6 4 3 22 27 27 27 13 Cdc37 C terminal domain PCSK9_C3 PF18463.1 PVD37720.1 - 4e-07 30.2 67.3 29 5.0 0.1 20.6 2 2 18 22 22 22 7 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Chorion_1 PF01723.16 PVD37720.1 - 0.00071 19.6 54.3 13 5.7 0.5 14.0 3 3 9 13 13 13 4 Chorion protein GLTP PF08718.11 PVD37721.1 - 9.7e-42 142.8 0.0 1.6e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.29 PVD37721.1 - 4.7e-11 43.1 0.0 8.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD37721.1 - 3.8e-05 24.1 0.0 0.0001 22.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Shisa PF13908.6 PVD37721.1 - 0.00089 19.5 11.4 0.17 12.1 0.0 3.1 3 0 0 3 3 3 2 Wnt and FGF inhibitory regulator FeoB_associated PF12669.7 PVD37721.1 - 1.2 9.6 6.1 4.9 7.6 6.1 2.0 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Isochorismatase PF00857.20 PVD37722.1 - 2e-21 76.9 0.1 4.4e-21 75.8 0.1 1.5 2 0 0 2 2 2 1 Isochorismatase family Herpes_teg_N PF04843.12 PVD37722.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region PTR2 PF00854.21 PVD37723.1 - 2e-101 339.7 6.0 1.4e-88 297.4 0.7 2.2 2 0 0 2 2 2 2 POT family DUF4397 PF14344.6 PVD37723.1 - 2.5e-10 41.2 0.3 0.00019 22.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4397) zf-C2H2 PF00096.26 PVD37724.1 - 1.2e-21 75.9 34.7 5.9e-06 26.5 4.7 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD37724.1 - 1.9e-19 69.2 23.9 1.8e-07 31.2 2.9 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD37724.1 - 3.7e-17 61.5 22.3 0.00011 22.7 0.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD37724.1 - 2e-09 37.2 24.8 0.0001 22.2 0.0 4.8 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PVD37724.1 - 3.2e-05 23.6 1.5 3.2e-05 23.6 1.5 4.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 PVD37724.1 - 0.0019 18.5 9.9 0.049 14.1 0.7 3.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PVD37724.1 - 0.0026 18.0 0.2 0.0026 18.0 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PVD37724.1 - 0.0085 15.9 1.3 2.4 8.0 0.0 3.3 3 0 0 3 3 3 1 GAGA factor zf-C2H2_9 PF16293.5 PVD37724.1 - 0.021 14.7 4.8 0.39 10.6 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 PVD37724.1 - 0.025 14.2 9.5 1 9.0 0.0 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger IBR PF01485.21 PVD37724.1 - 0.037 14.2 4.9 2.7 8.3 0.8 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_15 PF17032.5 PVD37724.1 - 0.056 14.2 9.2 1.1 10.1 0.3 2.7 2 1 0 3 3 2 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 PVD37724.1 - 0.074 13.5 0.1 0.074 13.5 0.1 3.1 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 PVD37724.1 - 0.078 12.7 5.4 0.44 10.2 2.9 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn-ribbon_8 PF09723.10 PVD37724.1 - 0.092 12.9 15.4 0.12 12.5 4.4 3.6 4 0 0 4 4 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 PVD37724.1 - 0.093 12.7 0.5 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.7 PVD37724.1 - 0.15 12.1 12.7 23 5.1 0.0 4.2 3 1 0 3 3 3 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 PVD37724.1 - 0.16 11.6 11.7 1.5 8.5 0.0 3.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 PVD37724.1 - 0.17 12.2 12.4 3.9 7.8 0.4 3.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 PVD37724.1 - 0.3 11.4 4.4 11 6.4 1.5 2.5 2 0 0 2 2 2 0 zinc-finger-containing domain HypA PF01155.19 PVD37724.1 - 0.44 10.6 3.7 34 4.5 3.6 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 PVD37724.1 - 1.7 9.0 17.1 0.36 11.2 3.0 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 PVD37724.1 - 2.4 8.1 9.0 4.5 7.3 3.5 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-LYAR PF08790.11 PVD37724.1 - 6.8 6.7 5.9 1.3 9.0 0.5 2.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger 4HBT_3 PF13622.6 PVD37727.1 - 0.02 15.2 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily BACK PF07707.15 PVD37728.1 - 2.7e-19 69.1 0.1 6.2e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 PVD37728.1 - 3e-17 61.9 1.9 0.00012 21.6 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PVD37728.1 - 1.1e-15 57.3 0.4 0.0026 17.7 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PVD37728.1 - 2.5e-15 56.1 0.0 0.00026 21.1 0.0 4.6 3 1 1 4 4 4 3 Kelch motif BTB PF00651.31 PVD37728.1 - 1.3e-14 54.3 0.1 2.6e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PVD37728.1 - 1.5e-11 44.2 0.1 0.02 15.2 0.1 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD37728.1 - 2.3e-11 43.2 2.3 0.023 14.7 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PVD37728.1 - 1.1e-08 34.8 0.5 0.058 13.4 0.0 5.3 5 0 0 5 5 5 2 Kelch motif DUF5590 PF17881.1 PVD37728.1 - 0.056 13.5 0.6 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) Tetraspanin PF00335.20 PVD37729.1 - 2.5e-54 184.4 15.8 2.8e-54 184.3 15.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 PVD37729.1 - 0.041 13.9 1.5 0.041 13.9 1.5 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Adeno_E3_CR2 PF02439.15 PVD37729.1 - 0.043 13.6 2.6 0.043 13.6 2.6 3.8 4 0 0 4 4 4 0 Adenovirus E3 region protein CR2 AA_permease_2 PF13520.6 PVD37729.1 - 0.22 10.3 16.2 0.0066 15.3 8.8 1.8 2 0 0 2 2 2 0 Amino acid permease AC_N PF16214.5 PVD37729.1 - 0.32 10.1 4.1 0.52 9.4 4.1 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region COX1 PF00115.20 PVD37729.1 - 0.61 8.9 12.1 0.018 13.9 6.1 1.4 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Arm PF00514.23 PVD37730.1 - 6.7e-64 210.2 20.5 9.4e-07 28.7 0.0 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD37730.1 - 2.5e-20 72.7 13.3 3.3e-05 24.2 1.9 7.7 2 2 6 8 8 8 6 HEAT repeats Adaptin_N PF01602.20 PVD37730.1 - 5.9e-12 44.9 0.2 0.00015 20.5 0.0 3.5 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 PVD37730.1 - 5.9e-11 42.6 12.1 0.00013 22.4 0.2 7.3 9 1 0 9 9 7 3 HEAT-like repeat V-ATPase_H_C PF11698.8 PVD37730.1 - 5.7e-10 39.3 4.9 1.6 8.8 0.1 6.8 3 3 4 7 7 7 4 V-ATPase subunit H HEAT PF02985.22 PVD37730.1 - 9.3e-10 37.9 14.8 0.99 9.8 0.2 8.4 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.13 PVD37730.1 - 2.8e-09 36.8 4.5 0.014 14.8 0.1 6.2 4 2 3 7 7 7 4 Armadillo-like Cnd1 PF12717.7 PVD37730.1 - 2.4e-07 30.9 1.1 0.99 9.4 0.0 5.4 4 1 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 PVD37730.1 - 3e-06 25.7 0.7 0.51 8.4 0.0 4.0 3 1 1 5 5 5 2 Kinesin-associated protein (KAP) UNC45-central PF11701.8 PVD37730.1 - 5.4e-06 26.4 0.8 0.02 14.9 0.0 4.0 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 PVD37730.1 - 1.9e-05 25.2 0.0 6.1 7.5 0.0 3.6 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region RTTN_N PF14726.6 PVD37730.1 - 0.043 14.6 1.9 29 5.5 0.0 5.5 6 1 1 7 7 6 0 Rotatin, an armadillo repeat protein, centriole functioning RasGEF_N_2 PF14663.6 PVD37730.1 - 0.16 12.4 3.9 96 3.4 0.1 5.5 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Hormone_recep PF00104.30 PVD37732.1 - 3.1e-25 89.0 1.4 4.6e-25 88.4 1.4 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 PVD37732.1 - 2.3e-12 47.2 1.5 6.2e-12 45.8 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DNA_primase_S PF01896.19 PVD37733.1 - 1.8e-56 191.0 0.5 2.8e-56 190.3 0.5 1.3 1 0 0 1 1 1 1 DNA primase small subunit ORC5_C PF14630.6 PVD37735.1 - 0.11 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus IPK PF03770.16 PVD37736.1 - 7.4e-38 130.4 0.9 2.7e-37 128.5 0.9 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Hydantoinase_B PF02538.14 PVD37736.1 - 0.022 13.2 0.0 0.028 12.8 0.0 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase 7tm_1 PF00001.21 PVD37737.1 - 5.3e-52 176.8 12.1 8.1e-52 176.1 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD37737.1 - 0.00053 19.8 11.8 0.0084 15.9 11.1 2.6 2 1 0 2 2 2 1 Olfactory receptor YrzO PF14142.6 PVD37737.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.0 2 0 0 2 2 2 0 YrzO-like protein Shisa PF13908.6 PVD37737.1 - 1.7 8.9 6.4 4.3 7.5 0.4 3.1 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Astacin PF01400.24 PVD37740.1 - 5.3e-64 215.4 2.3 8e-64 214.8 2.3 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 PVD37740.1 - 3.3e-39 134.4 1.1 4.1e-34 117.8 0.0 2.8 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Peptidase_M10 PF00413.24 PVD37740.1 - 0.0044 16.9 2.8 3.2 7.6 0.7 3.4 2 1 1 3 3 3 2 Matrixin Lipl32 PF12103.8 PVD37740.1 - 0.13 11.9 0.2 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Myosin_head PF00063.21 PVD37741.1 - 4.1e-207 689.6 2.7 7.1e-207 688.8 2.7 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 PVD37741.1 - 1.4e-55 188.5 0.4 5.4e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD37741.1 - 4.9e-40 137.4 0.0 8.9e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 PVD37741.1 - 1.5e-13 49.2 33.9 1.7e-05 24.2 0.8 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Pkinase_fungal PF17667.1 PVD37741.1 - 1.5e-05 24.0 0.1 1.5e-05 24.0 0.1 2.5 2 1 0 2 2 1 1 Fungal protein kinase AAA_22 PF13401.6 PVD37741.1 - 0.00014 22.1 0.0 0.0008 19.7 0.0 2.3 1 0 0 1 1 1 1 AAA domain RIO1 PF01163.22 PVD37741.1 - 0.0019 17.8 0.2 0.0019 17.8 0.2 2.6 3 1 0 3 3 1 1 RIO1 family APH PF01636.23 PVD37741.1 - 0.032 14.2 0.0 0.29 11.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ig_GlcNase PF18368.1 PVD37741.1 - 0.072 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain RsgA_GTPase PF03193.16 PVD37741.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Peptidase_C3 PF00548.20 PVD37741.1 - 0.17 11.8 0.9 0.44 10.5 0.9 1.6 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) AAA_16 PF13191.6 PVD37741.1 - 0.25 11.7 1.4 0.81 10.0 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain Phage_Gp23 PF10669.9 PVD37741.1 - 3.8 7.9 8.6 10 6.5 8.6 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-C2H2 PF00096.26 PVD37743.1 - 3e-12 46.3 35.8 2.1e-06 27.9 0.8 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD37743.1 - 9e-12 44.9 6.4 1.3e-07 31.7 1.0 5.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD37743.1 - 3.1e-06 27.6 8.6 0.00028 21.5 1.6 6.1 7 0 0 7 7 7 3 C2H2-type zinc finger zf-LYAR PF08790.11 PVD37743.1 - 0.22 11.5 1.9 4.8 7.2 0.3 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger PP2C PF00481.21 PVD37745.1 - 4.1e-34 118.4 5.0 2.7e-27 96.0 0.0 3.3 3 0 0 3 3 3 3 Protein phosphatase 2C zf_UBZ PF18439.1 PVD37745.1 - 0.02 14.5 0.8 0.055 13.1 0.8 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger EF-hand_6 PF13405.6 PVD37746.1 - 6.2e-08 32.0 2.1 0.003 17.3 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PVD37746.1 - 2e-07 30.1 8.6 0.0027 17.1 0.5 3.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 PVD37746.1 - 9.4e-07 29.2 2.6 4.1e-06 27.1 2.5 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD37746.1 - 4.2e-06 26.0 0.8 0.037 13.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD37746.1 - 0.0047 16.7 0.6 0.054 13.4 0.9 2.5 2 1 0 2 2 2 1 EF-hand domain pair DUF5580 PF17743.1 PVD37746.1 - 0.0086 14.7 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1825 PF08855.10 PVD37746.1 - 0.15 12.0 2.9 3.9 7.5 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) EF-hand_4 PF12763.7 PVD37746.1 - 0.23 11.4 0.5 0.7 9.9 0.5 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 PVD37747.1 - 3.3e-62 208.9 0.3 3.8e-62 208.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD37747.1 - 1.7e-35 121.8 0.0 3.2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD37747.1 - 1.5e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD37747.1 - 3.9e-05 23.1 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD37747.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD37747.1 - 0.00016 21.6 0.1 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD37747.1 - 0.0003 20.4 0.0 0.00059 19.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PVD37747.1 - 0.019 15.3 0.1 0.033 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PVD37747.1 - 0.027 14.7 0.2 1.4 9.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain MCR_beta PF02241.18 PVD37747.1 - 0.04 13.5 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Ras PF00071.22 PVD37748.1 - 1.8e-55 186.9 0.1 2.7e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD37748.1 - 2e-34 118.3 1.5 2.3e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD37748.1 - 3.7e-13 49.3 0.0 5.1e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD37748.1 - 3.5e-05 23.3 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PVD37748.1 - 0.00018 21.5 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PVD37748.1 - 0.00033 20.6 0.2 0.69 9.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PVD37748.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PVD37748.1 - 0.029 14.8 0.1 0.057 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 PVD37748.1 - 0.13 12.2 0.1 0.29 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PVD37748.1 - 0.14 11.8 0.1 0.44 10.2 0.0 1.8 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 PVD37748.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Astacin PF01400.24 PVD37749.1 - 4.8e-40 137.2 0.0 7.3e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Protocadherin PF08374.11 PVD37749.1 - 0.056 13.4 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Reprolysin_4 PF13583.6 PVD37749.1 - 0.12 12.0 0.2 0.53 9.9 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD37749.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Matrixin Galactosyl_T PF01762.21 PVD37752.1 - 4.7e-41 140.8 0.0 6.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase AAA_33 PF13671.6 PVD37753.1 - 2.8e-25 89.2 0.1 5.7e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 PVD37753.1 - 3.1e-14 53.1 0.0 7.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 SPRY domain AAA_18 PF13238.6 PVD37753.1 - 0.00043 20.8 0.0 0.00087 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PVD37753.1 - 0.044 13.1 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PNISR PF15996.5 PVD37753.1 - 0.31 11.3 7.5 1.1 9.5 7.5 1.9 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF3456 PF11938.8 PVD37754.1 - 1.2e-44 152.6 2.1 1.5e-44 152.2 2.1 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP CTP_transf_1 PF01148.20 PVD37755.1 - 6.6e-45 153.9 25.0 2.3e-29 103.0 4.5 2.1 1 1 0 2 2 2 2 Cytidylyltransferase family MCU PF04678.13 PVD37757.1 - 2.5e-62 210.1 0.2 3.3e-62 209.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Trimer_CC PF08954.11 PVD37757.1 - 0.13 11.9 0.9 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Trimerisation motif Syntaxin-6_N PF09177.11 PVD37757.1 - 0.31 11.6 2.5 21 5.7 0.6 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 PVD37757.1 - 3.1 8.1 7.1 16 5.8 0.8 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain THAP PF05485.12 PVD37758.1 - 2.6e-05 25.1 0.6 8.8e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 THAP domain G_glu_transpept PF01019.21 PVD37759.1 - 5e-123 411.6 0.0 4.8e-94 315.9 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase ABC2_membrane_3 PF12698.7 PVD37760.1 - 1.3e-53 182.4 52.0 9.6e-40 136.7 16.1 4.2 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 PVD37760.1 - 5.1e-48 163.1 0.0 3e-25 89.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PVD37760.1 - 3.2e-17 63.3 0.0 1.1e-06 28.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 PVD37760.1 - 2.1 8.1 5.1 0.57 10.0 0.2 2.4 3 0 0 3 3 3 0 MukB N-terminal Cript PF10235.9 PVD37761.1 - 5.7 7.6 8.4 0.43 11.2 0.4 3.3 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT ThiF PF00899.21 PVD37762.1 - 1.4e-39 135.9 0.1 3.6e-35 121.5 0.1 2.2 1 1 1 2 2 2 2 ThiF family UDPG_MGDP_dh_N PF03721.14 PVD37762.1 - 0.0028 17.2 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TSC22 PF01166.18 PVD37762.1 - 0.029 14.7 2.3 0.038 14.3 0.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family TrkA_N PF02254.18 PVD37762.1 - 0.042 14.1 0.0 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Pox_A_type_inc PF04508.12 PVD37762.1 - 0.045 13.6 0.4 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat FAD_binding_3 PF01494.19 PVD37762.1 - 0.075 12.3 0.3 0.15 11.3 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 PVD37762.1 - 0.079 13.2 1.3 1.2 9.4 1.3 2.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 PVD37762.1 - 0.089 12.1 0.0 0.23 10.8 0.0 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HSBP1 PF06825.12 PVD37762.1 - 0.12 12.3 1.8 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 p25-alpha PF05517.12 PVD37763.1 - 2.8e-29 102.3 8.6 3.9e-29 101.8 8.6 1.2 1 0 0 1 1 1 1 p25-alpha PKD_channel PF08016.12 PVD37764.1 - 4.7e-79 266.0 20.0 5.4e-79 265.9 20.0 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PVD37764.1 - 2.7e-07 30.1 29.8 4.8e-07 29.3 29.8 1.3 1 0 0 1 1 1 1 Ion transport protein SieB PF14163.6 PVD37764.1 - 1 8.9 6.4 1.1 8.8 0.3 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B REJ PF02010.15 PVD37765.1 - 3.8e-36 124.8 5.7 8.3e-36 123.7 5.7 1.5 1 0 0 1 1 1 1 REJ domain PLAT PF01477.23 PVD37765.1 - 7.9e-14 52.2 0.1 5e-13 49.6 0.1 2.5 2 0 0 2 2 2 1 PLAT/LH2 domain PKD PF00801.20 PVD37765.1 - 2.5e-12 46.5 50.5 1.3e-06 28.1 0.4 9.3 9 0 0 9 9 9 5 PKD domain GPS PF01825.21 PVD37765.1 - 4.3e-06 27.2 0.5 2e-05 25.0 0.5 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PKD_channel PF08016.12 PVD37765.1 - 1.6e-05 23.8 0.2 8.2e-05 21.5 0.0 2.3 3 0 0 3 3 3 1 Polycystin cation channel GDPD PF03009.17 PVD37766.1 - 3.4e-21 76.2 0.7 4.7e-21 75.7 0.7 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Homeodomain PF00046.29 PVD37768.1 - 2.2e-22 78.6 4.3 3.8e-22 77.9 4.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PVD37768.1 - 0.12 12.3 0.8 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain Cadherin PF00028.17 PVD37769.1 - 6.1e-140 456.1 35.4 2.7e-15 56.6 0.9 14.0 13 1 0 13 13 13 11 Cadherin domain Cadherin_3 PF16184.5 PVD37769.1 - 2.8e-20 72.4 33.6 0.00011 22.2 1.1 11.7 12 0 0 12 12 12 6 Cadherin-like Cadherin_2 PF08266.12 PVD37769.1 - 3.8e-12 45.9 3.0 0.17 11.7 0.0 8.6 10 0 0 10 10 10 3 Cadherin-like RET_CLD1 PF17756.1 PVD37769.1 - 0.0027 18.0 2.1 0.5 10.7 0.0 5.1 7 0 0 7 7 7 1 RET Cadherin like domain 1 TMEM132D_C PF15706.5 PVD37769.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cadherin_4 PF17803.1 PVD37769.1 - 0.47 11.1 100.4 0.091 13.4 1.7 13.5 13 1 0 13 13 13 0 Bacterial cadherin-like domain Syndecan PF01034.20 PVD37769.1 - 2.7 8.0 4.5 6 6.9 4.5 1.5 1 0 0 1 1 1 0 Syndecan domain Cadherin PF00028.17 PVD37770.1 - 1.1e-291 942.5 83.4 2e-23 82.6 0.1 24.0 24 0 0 24 24 24 22 Cadherin domain Cadherin_3 PF16184.5 PVD37770.1 - 1.2e-25 89.7 58.5 0.028 14.4 0.3 19.4 19 0 0 19 19 19 10 Cadherin-like Cadherin_2 PF08266.12 PVD37770.1 - 6.4e-16 58.0 0.0 4.4 7.2 0.0 14.2 16 0 0 16 16 16 3 Cadherin-like RET_CLD1 PF17756.1 PVD37770.1 - 8.3e-06 26.1 3.4 1.7 8.9 0.0 7.7 9 0 0 9 9 9 1 RET Cadherin like domain 1 DUF3364 PF11844.8 PVD37770.1 - 0.0033 17.6 0.0 11 6.4 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3364) NAGLU_N PF12971.7 PVD37770.1 - 0.078 12.8 0.1 1.8e+02 2.0 0.0 5.1 4 0 0 4 4 4 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF4442 PF14539.6 PVD37770.1 - 0.59 10.3 3.4 23 5.1 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4442) DUF5011 PF16403.5 PVD37770.1 - 1.9 8.7 17.2 33 4.7 0.0 7.0 6 0 0 6 6 6 0 Domain of unknown function (DUF5011) Cadherin PF00028.17 PVD37771.1 - 1.4e-201 653.7 46.0 2.5e-20 72.7 0.1 18.0 18 1 0 18 18 18 16 Cadherin domain Cadherin_3 PF16184.5 PVD37771.1 - 3.9e-20 71.9 35.4 0.053 13.5 0.3 13.5 14 0 0 14 14 14 7 Cadherin-like C1q PF00386.21 PVD37771.1 - 1.3e-17 64.2 0.0 1.1e-16 61.3 0.0 2.6 2 0 0 2 2 2 1 C1q domain Cadherin_2 PF08266.12 PVD37771.1 - 5.7e-13 48.5 0.0 1.5 8.7 0.0 9.7 11 0 0 11 11 11 4 Cadherin-like DUF5011 PF16403.5 PVD37771.1 - 0.029 14.5 4.6 11 6.2 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) MG1 PF17790.1 PVD37771.1 - 0.14 12.6 8.7 9.6 6.7 0.1 6.0 7 0 0 7 7 7 0 Macroglobulin domain MG1 Cadherin PF00028.17 PVD37772.1 - 2.7e-89 293.8 0.0 5.1e-22 78.1 0.0 9.1 7 2 1 8 8 8 6 Cadherin domain C1q PF00386.21 PVD37772.1 - 8.7e-41 139.1 4.6 1.1e-19 70.9 0.1 2.9 2 0 0 2 2 2 2 C1q domain Cadherin_3 PF16184.5 PVD37772.1 - 4.2e-09 36.4 2.0 0.11 12.6 0.0 6.4 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 PVD37772.1 - 1.7e-06 27.8 0.0 1.2 9.0 0.0 5.2 5 0 0 5 5 5 2 Cadherin-like PA14 PF07691.12 PVD37772.1 - 0.0017 18.2 0.6 0.5 10.2 0.0 3.2 2 1 0 2 2 2 1 PA14 domain ChitinaseA_N PF08329.10 PVD37772.1 - 0.01 15.5 0.2 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Chitinase A, N-terminal domain PPC PF04151.15 PVD37772.1 - 0.18 12.9 4.6 36 5.6 0.0 4.6 4 1 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Cadherin PF00028.17 PVD37773.1 - 6e-60 199.7 0.6 9.1e-20 70.9 0.0 4.6 4 0 0 4 4 4 4 Cadherin domain C1q PF00386.21 PVD37773.1 - 2.6e-20 72.9 0.1 5.8e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 C1q domain Cadherin_3 PF16184.5 PVD37773.1 - 3.2e-11 43.2 3.7 0.00026 20.9 0.1 4.7 4 0 0 4 4 4 4 Cadherin-like PA14 PF07691.12 PVD37773.1 - 0.12 12.2 0.5 0.59 9.9 0.0 2.4 3 0 0 3 3 3 0 PA14 domain Cadherin_2 PF08266.12 PVD37773.1 - 0.13 12.1 0.0 7.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Cadherin-like Glyco_hydro_18 PF00704.28 PVD37774.1 - 1.7e-77 261.2 0.0 2.1e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SBP56 PF05694.11 PVD37774.1 - 0.19 10.5 0.0 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Glyco_hydro_18 PF00704.28 PVD37775.1 - 1.8e-68 231.6 0.1 3.2e-66 224.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CD225 PF04505.12 PVD37776.1 - 3.1e-07 30.4 0.3 4.8e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein YqfD PF06898.11 PVD37776.1 - 0.13 11.1 0.2 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DUF2109 PF09882.9 PVD37776.1 - 2.5 8.2 5.8 0.14 12.2 0.6 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) 7tm_1 PF00001.21 PVD37780.1 - 2.1e-34 119.0 14.2 3.7e-34 118.3 14.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD37780.1 - 6.3e-08 32.6 5.5 6.3e-08 32.6 5.5 2.6 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD37780.1 - 0.12 12.1 17.7 2.1 8.0 17.0 2.7 1 1 1 2 2 2 0 Olfactory receptor SRCR PF00530.18 PVD37781.1 - 0 1205.2 133.2 1.5e-21 76.8 1.5 24.5 24 1 0 24 24 24 24 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37781.1 - 1.3e-71 237.3 100.1 2.3e-05 24.8 0.4 23.7 24 0 0 24 24 24 17 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37781.1 - 2.8e-31 108.3 41.7 0.092 13.3 0.1 20.1 22 0 0 22 22 22 11 Hepsin, SRCR domain Pep_deformylase PF01327.21 PVD37781.1 - 0.00017 21.2 0.0 0.84 9.2 0.0 2.7 2 0 0 2 2 2 2 Polypeptide deformylase YecR PF13992.6 PVD37781.1 - 6.8 7.1 39.5 6.4 7.2 0.0 13.8 17 0 0 17 17 17 0 YecR-like lipoprotein SRCR PF00530.18 PVD37782.1 - 6.3e-52 174.2 31.1 5.8e-12 46.0 0.0 7.1 7 0 0 7 7 7 7 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37782.1 - 6e-15 55.6 15.2 8.5e-05 23.0 0.4 5.8 5 1 0 5 5 5 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37782.1 - 3.5e-07 30.7 5.7 0.002 18.6 0.1 5.0 5 0 0 5 5 5 2 Hepsin, SRCR domain SSI PF00720.17 PVD37782.1 - 0.0073 16.2 0.1 12 5.9 0.0 4.0 4 0 0 4 4 4 1 Subtilisin inhibitor-like YecR PF13992.6 PVD37782.1 - 0.9 9.9 4.4 3.4 8.0 0.0 3.8 4 0 0 4 4 4 0 YecR-like lipoprotein SRCR PF00530.18 PVD37783.1 - 4.1e-34 117.1 2.9 8.7e-20 71.1 0.0 2.8 2 1 1 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37783.1 - 2.2e-10 40.9 1.9 9.8e-05 22.8 1.4 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37783.1 - 0.00043 20.8 0.6 0.13 12.7 0.2 2.3 2 0 0 2 2 2 2 Hepsin, SRCR domain SRCR PF00530.18 PVD37784.1 - 3e-110 361.4 36.6 3.1e-17 62.9 1.4 8.1 8 0 0 8 8 8 8 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37784.1 - 3e-23 82.2 28.2 0.00017 22.1 2.0 7.2 6 2 0 6 6 6 6 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37784.1 - 2.2e-09 37.8 16.9 0.057 13.9 0.5 7.6 7 1 0 7 7 7 5 Hepsin, SRCR domain SRCR PF00530.18 PVD37785.1 - 0 1313.0 151.0 4.1e-22 78.6 0.5 30.1 28 2 2 30 30 30 30 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PVD37785.1 - 3.2e-81 268.1 110.6 1e-05 26.0 0.0 27.4 27 0 0 27 27 27 21 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD37785.1 - 6e-27 94.3 55.2 0.25 11.9 0.4 23.7 25 1 1 26 26 26 10 Hepsin, SRCR domain BURP PF03181.15 PVD37785.1 - 0.027 14.0 1.5 3.6 7.1 0.1 2.7 2 0 0 2 2 2 0 BURP domain Pep_deformylase PF01327.21 PVD37785.1 - 0.11 12.1 0.0 20 4.7 0.0 2.7 2 0 0 2 2 2 0 Polypeptide deformylase SKG6 PF08693.10 PVD37785.1 - 0.16 11.4 7.1 0.4 10.1 7.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RBD-FIP PF09457.10 PVD37786.1 - 0.0084 16.0 0.3 0.022 14.6 0.3 1.8 1 1 0 1 1 1 1 FIP domain TIG PF01833.24 PVD37786.1 - 0.04 14.0 0.3 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 IPT/TIG domain C2 PF00168.30 PVD37787.1 - 2.1e-08 34.4 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain NERD PF08378.11 PVD37788.1 - 0.0016 18.9 0.0 0.0044 17.5 0.0 1.8 1 0 0 1 1 1 1 Nuclease-related domain NAR2 PF16974.5 PVD37788.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Pro_isomerase PF00160.21 PVD37789.1 - 8.6e-93 308.8 1.7 3.6e-46 157.3 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 PVD37790.1 - 7.8e-50 169.2 0.1 9.2e-50 169.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PPR_2 PF13041.6 PVD37791.1 - 0.0042 17.3 0.1 0.061 13.5 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 PVD37791.1 - 0.014 15.6 0.1 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 PPR repeat Plasmid_stab_B PF10784.9 PVD37791.1 - 0.14 12.0 0.1 0.42 10.5 0.1 1.8 1 1 0 1 1 1 0 Plasmid stability protein ADH_N PF08240.12 PVD37792.1 - 3.5e-29 100.9 1.5 7.3e-29 99.8 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PVD37792.1 - 1.4e-23 83.3 0.1 2.9e-23 82.3 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PVD37792.1 - 3.3e-09 36.6 0.6 1.8e-08 34.1 0.6 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 PVD37792.1 - 0.00015 21.1 1.9 0.00027 20.3 1.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 PVD37792.1 - 0.00048 21.2 0.0 0.00086 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 PVD37792.1 - 0.036 13.7 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 PVD37792.1 - 0.066 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_16 PF10294.9 PVD37792.1 - 0.22 11.3 0.1 0.34 10.6 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Calx-beta PF03160.14 PVD37793.1 - 6.7e-252 815.6 109.7 1.6e-16 60.3 0.2 40.9 40 2 1 41 41 41 33 Calx-beta domain EPTP PF03736.17 PVD37793.1 - 4.1e-40 135.5 14.4 7e-11 41.9 0.1 7.3 7 0 0 7 7 7 5 EPTP domain Laminin_G_3 PF13385.6 PVD37793.1 - 4.8e-21 75.5 2.1 4.8e-21 75.5 2.1 4.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.24 PVD37793.1 - 2e-14 53.5 25.6 3.2e-14 52.8 25.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 PVD37793.1 - 0.0014 19.1 2.3 0.0031 18.0 2.3 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Laminin_G_2 PF02210.24 PVD37793.1 - 0.06 13.9 0.1 0.39 11.3 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain SET PF00856.28 PVD37794.1 - 1.2e-18 68.0 1.6 1.3e-17 64.7 0.4 3.5 2 1 0 2 2 2 1 SET domain BAH PF01426.18 PVD37794.1 - 1.9e-17 63.3 0.1 5.8e-17 61.7 0.1 1.9 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 PVD37794.1 - 2.4e-16 59.6 0.0 7.3e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AWS PF17907.1 PVD37794.1 - 3.8e-14 52.4 8.6 3.8e-14 52.4 8.6 2.5 2 0 0 2 2 2 1 AWS domain PHD PF00628.29 PVD37794.1 - 8.6e-05 22.4 12.7 8.6e-05 22.4 12.7 2.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PVD37794.1 - 1.3 8.6 9.4 2.9 7.5 9.4 1.6 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 PVD37795.1 - 0.25 12.3 4.6 3.3 8.7 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat TPH PF13868.6 PVD37796.1 - 4.8e-25 87.8 147.3 4.8e-25 87.8 147.3 2.5 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain C1q PF00386.21 PVD37797.1 - 2.2e-16 60.2 0.0 1.7e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 C1q domain HAUS-augmin3 PF14932.6 PVD37797.1 - 0.00036 20.2 0.7 0.00036 20.2 0.7 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 Laminin_I PF06008.14 PVD37797.1 - 0.00086 19.1 8.8 0.05 13.3 1.3 2.2 2 0 0 2 2 2 2 Laminin Domain I BRE1 PF08647.11 PVD37797.1 - 0.0011 19.0 1.2 0.0011 19.0 1.2 2.1 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase GAS PF13851.6 PVD37797.1 - 0.011 15.0 5.2 0.2 11.0 0.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PilJ PF13675.6 PVD37797.1 - 0.017 15.1 0.3 0.017 15.1 0.3 3.0 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.6 PVD37797.1 - 0.022 14.1 2.3 0.22 10.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 PVD37797.1 - 0.043 14.6 3.8 0.079 13.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) FPP PF05911.11 PVD37797.1 - 0.043 12.0 0.2 0.27 9.4 0.0 1.9 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 PVD37797.1 - 0.059 13.9 6.4 2.8 8.5 0.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 PVD37797.1 - 0.08 13.2 6.9 2.4 8.5 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HPD PF05044.12 PVD37797.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.7 1 1 0 1 1 1 0 Homeo-prospero domain YabA PF06156.13 PVD37797.1 - 0.13 12.9 2.2 1.4 9.6 0.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA YscO-like PF16789.5 PVD37797.1 - 0.19 11.8 3.4 0.087 12.9 0.8 1.7 2 0 0 2 2 2 0 YscO-like protein Syntaxin_2 PF14523.6 PVD37797.1 - 0.19 12.1 3.4 1.8 9.0 0.6 2.3 2 0 0 2 2 2 0 Syntaxin-like protein RNase_E_G PF10150.9 PVD37797.1 - 0.2 11.0 1.8 0.25 10.7 0.4 1.7 2 0 0 2 2 2 0 Ribonuclease E/G family Tektin PF03148.14 PVD37797.1 - 0.3 9.8 4.3 1.1 7.9 0.4 2.1 2 0 0 2 2 2 0 Tektin family DUF1664 PF07889.12 PVD37797.1 - 0.31 11.1 5.0 3.4 7.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 PVD37797.1 - 0.55 10.3 7.2 0.89 9.6 0.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.9 PVD37797.1 - 0.55 9.6 4.6 4.6 6.5 0.3 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4795 PF16043.5 PVD37797.1 - 0.57 9.7 3.1 2.2 7.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 PVD37797.1 - 0.66 8.8 6.3 0.25 10.2 0.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_lysis PF03245.13 PVD37797.1 - 0.77 9.9 8.6 0.2 11.8 0.2 3.0 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein CENP-F_leu_zip PF10473.9 PVD37797.1 - 0.93 9.5 7.9 0.86 9.6 1.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT20 PF14931.6 PVD37797.1 - 0.95 9.6 4.9 0.54 10.4 0.3 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 T3SSipB PF16535.5 PVD37797.1 - 1.1 9.8 6.5 0.22 12.0 1.4 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB ZapB PF06005.12 PVD37797.1 - 1.2 9.6 10.9 8.5 6.9 2.0 2.8 2 0 0 2 2 2 0 Cell division protein ZapB DegS PF05384.11 PVD37797.1 - 1.4 8.4 6.7 0.47 9.9 0.6 2.3 2 0 0 2 2 2 0 Sensor protein DegS JIP_LZII PF16471.5 PVD37797.1 - 5.5 7.2 8.5 16 5.7 0.8 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1397 PF07165.11 PVD37799.1 - 0.027 13.9 0.6 0.04 13.3 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) PIRT PF15099.6 PVD37804.1 - 0.022 14.3 0.3 0.04 13.5 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DHHC PF01529.20 PVD37804.1 - 0.78 9.9 5.2 1.1 9.3 5.0 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase CBM_14 PF01607.24 PVD37806.1 - 1.9e-20 72.8 38.7 4.8e-12 45.9 5.6 3.9 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 PVD37807.1 - 1.1e-24 86.4 27.5 4.4e-11 42.8 4.2 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain AAA_18 PF13238.6 PVD37808.1 - 4.3e-28 98.5 0.0 6.9e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD37808.1 - 4.5e-07 30.1 0.0 0.0003 21.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 PVD37808.1 - 5.2e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 PVD37808.1 - 3.1e-06 27.6 0.0 6.9e-06 26.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 PVD37808.1 - 1.4e-05 25.5 0.1 4.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 PVD37808.1 - 1.5e-05 25.2 0.7 0.003 17.7 0.0 2.8 2 1 1 3 3 3 1 Shikimate kinase RNA_helicase PF00910.22 PVD37808.1 - 1.9e-05 25.0 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 PVD37808.1 - 2.9e-05 24.5 0.2 5.4e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PVD37808.1 - 3.6e-05 23.8 0.0 8.4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD37808.1 - 0.0002 21.7 0.1 0.00048 20.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 PVD37808.1 - 0.00041 20.1 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PVD37808.1 - 0.0008 18.8 0.5 0.0026 17.1 0.1 1.8 2 0 0 2 2 2 1 KaiC dNK PF01712.19 PVD37808.1 - 0.00096 19.1 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase NTPase_1 PF03266.15 PVD37808.1 - 0.0024 17.8 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 NTPase Cytidylate_kin2 PF13189.6 PVD37808.1 - 0.0028 17.8 0.1 0.0041 17.3 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family DUF2075 PF09848.9 PVD37808.1 - 0.0032 16.7 0.0 0.0055 16.0 0.0 1.4 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) CoaE PF01121.20 PVD37808.1 - 0.0041 16.8 0.1 0.015 15.0 0.1 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase KTI12 PF08433.10 PVD37808.1 - 0.0045 16.5 0.0 0.01 15.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_25 PF13481.6 PVD37808.1 - 0.0064 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PVD37808.1 - 0.0068 16.2 0.0 0.033 13.9 0.0 1.8 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 PVD37808.1 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 PVD37808.1 - 0.0082 15.4 0.0 0.02 14.2 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 PVD37808.1 - 0.0087 15.8 0.4 0.84 9.3 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase RuvB_N PF05496.12 PVD37808.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PVD37808.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 PVD37808.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 PVD37808.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 PVD37808.1 - 0.021 15.2 0.1 0.044 14.1 0.1 1.5 2 0 0 2 2 1 0 AAA domain ADK PF00406.22 PVD37808.1 - 0.021 14.9 0.2 0.84 9.7 0.1 2.3 2 1 0 2 2 2 0 Adenylate kinase Cytidylate_kin PF02224.18 PVD37808.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_14 PF13173.6 PVD37808.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PVD37808.1 - 0.027 14.5 0.1 0.1 12.7 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 PVD37808.1 - 0.037 13.7 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PVD37808.1 - 0.041 13.6 0.5 0.074 12.8 0.5 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain IPT PF01745.16 PVD37808.1 - 0.042 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_11 PF13086.6 PVD37808.1 - 0.046 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PVD37808.1 - 0.047 12.7 0.2 0.083 11.9 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 PVD37808.1 - 0.056 12.7 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 PVD37808.1 - 0.057 12.9 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 PVD37808.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 PVD37808.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 PVD37808.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 PVD37808.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PVD37808.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain GTP_EFTU PF00009.27 PVD37808.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 PVD37808.1 - 0.11 11.9 0.1 0.23 10.9 0.0 1.7 2 1 0 2 2 1 0 Bacterial TniB protein SRP54 PF00448.22 PVD37808.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Hydin_ADK PF17213.3 PVD37808.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FtsK_SpoIIIE PF01580.18 PVD37808.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Hpr_kinase_C PF07475.12 PVD37808.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 1 0 HPr Serine kinase C-terminal domain APS_kinase PF01583.20 PVD37808.1 - 0.12 12.3 0.1 0.31 10.9 0.1 1.7 1 1 1 2 2 2 0 Adenylylsulphate kinase MeaB PF03308.16 PVD37808.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 PVD37808.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 PVD37808.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 PVD37808.1 - 0.29 11.7 1.2 0.68 10.4 0.2 2.0 2 1 1 3 3 2 0 ABC transporter PARP PF00644.20 PVD37809.1 - 2.4e-23 82.8 0.1 3.4e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 PVD37809.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Exotoxin A catalytic Atx10homo_assoc PF09759.9 PVD37810.1 - 3.2e-06 27.1 8.2 0.0011 19.0 0.6 4.1 2 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 PVD37810.1 - 0.00012 22.0 5.5 0.11 12.6 0.1 5.2 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat PAH PF02671.21 PVD37810.1 - 0.00068 19.7 0.1 0.003 17.7 0.0 2.0 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF3361 PF11841.8 PVD37810.1 - 0.0081 16.1 0.3 0.0081 16.1 0.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) DUF4456 PF14644.6 PVD37810.1 - 0.59 9.8 2.7 0.37 10.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) RNA_GG_bind PF10258.9 PVD37812.1 - 5.1e-31 106.6 1.9 1.1e-30 105.5 0.8 2.1 2 0 0 2 2 2 1 PHAX RNA-binding domain Dynactin_p22 PF07426.11 PVD37813.1 - 5.4e-30 104.4 4.9 6.5e-30 104.2 4.9 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 La PF05383.17 PVD37814.1 - 8.4e-09 35.4 0.1 1.8e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 La domain SUZ-C PF12901.7 PVD37814.1 - 3.2e-05 23.8 0.1 9.5e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 PVD37814.1 - 0.0037 17.0 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RQC PF09382.10 PVD37815.1 - 4.9e-21 74.6 0.2 9.7e-21 73.7 0.2 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 PVD37815.1 - 3.5e-20 72.5 0.0 1.3e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37815.1 - 2.5e-18 66.4 0.0 1.4e-16 60.8 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PVD37815.1 - 5.7e-18 65.4 5.7 2.3e-17 63.5 5.7 2.2 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 PVD37815.1 - 8.4e-11 41.7 0.0 2.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 PVD37815.1 - 0.029 14.4 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Abhydrolase_1 PF00561.20 PVD37817.1 - 3.5e-25 89.1 0.4 1.5e-18 67.4 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PVD37817.1 - 9.1e-22 78.7 0.1 1.2e-20 75.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PVD37817.1 - 3.9e-19 68.9 0.0 2.1e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 PVD37817.1 - 8.8e-06 25.7 0.0 0.00037 20.4 0.0 2.6 2 1 0 2 2 2 1 Serine hydrolase DLH PF01738.18 PVD37817.1 - 0.00045 19.8 0.1 1.3 8.6 0.0 2.8 2 1 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 PVD37817.1 - 0.0013 18.4 0.0 0.021 14.5 0.0 2.6 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 PVD37817.1 - 0.0045 16.8 0.1 3.3 7.4 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 PVD37817.1 - 0.0046 17.1 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Chlorophyllase2 PF12740.7 PVD37817.1 - 0.0079 15.1 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Chlorophyllase enzyme Ndr PF03096.14 PVD37817.1 - 0.014 14.2 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 0 Ndr family Lipase_3 PF01764.25 PVD37817.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 PVD37817.1 - 0.019 15.1 1.5 0.94 9.5 0.0 2.5 2 1 0 2 2 2 0 Thioesterase domain Chlorophyllase PF07224.11 PVD37817.1 - 0.039 13.0 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase DUF2920 PF11144.8 PVD37817.1 - 0.045 12.9 0.1 0.6 9.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2920) F-box-like PF12937.7 PVD37818.1 - 5.6e-10 38.9 3.7 5.6e-10 38.9 3.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD37818.1 - 5.4e-09 35.7 0.9 2e-08 33.9 0.9 2.0 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PVD37818.1 - 0.0039 16.7 0.2 0.0084 15.7 0.2 1.5 1 0 0 1 1 1 1 F-box DUF3987 PF13148.6 PVD37819.1 - 1.3e-21 77.0 0.0 3.5e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Ank_5 PF13857.6 PVD37820.1 - 1.8e-10 40.8 1.5 0.0027 18.0 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD37820.1 - 4.5e-10 40.0 0.1 5.9e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37820.1 - 1e-09 38.7 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD37820.1 - 7e-06 26.3 1.0 0.00012 22.3 0.2 2.7 2 1 1 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 PVD37820.1 - 3.1e-05 24.0 0.4 0.018 15.5 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat BPA_C PF18040.1 PVD37820.1 - 0.046 13.6 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 beta porphyranase A C-terminal Ank_2 PF12796.7 PVD37821.1 - 8.2e-45 151.3 11.4 3.6e-13 49.9 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37821.1 - 1.1e-39 134.3 7.0 9e-11 42.1 0.1 5.8 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PVD37821.1 - 6.6e-39 130.7 12.0 6.3e-06 26.4 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 PVD37821.1 - 1.5e-38 130.3 12.5 6.6e-09 35.9 0.4 7.9 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD37821.1 - 7.4e-37 121.2 7.7 6.4e-05 23.0 0.1 8.7 8 0 0 8 8 8 8 Ankyrin repeat Death PF00531.22 PVD37821.1 - 1.1e-09 38.3 0.2 2.2e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Death domain 3HCDH_RFF PF18321.1 PVD37821.1 - 0.0044 17.4 4.1 3.7 8.1 0.0 3.9 4 0 0 4 4 4 2 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain VWA_3_C PF18571.1 PVD37821.1 - 0.82 9.6 4.5 8.8 6.3 0.3 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Filament PF00038.21 PVD37822.1 - 1.5e-70 238.3 62.9 1.3e-68 231.9 62.9 2.1 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 PVD37822.1 - 3.4e-16 59.6 0.2 6.5e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Lamin Tail Domain APG6_N PF17675.1 PVD37822.1 - 0.0056 17.2 20.4 0.0056 17.2 20.4 4.8 1 1 4 5 5 5 1 Apg6 coiled-coil region TACC_C PF05010.14 PVD37822.1 - 0.0079 16.0 42.7 0.074 12.8 7.4 2.7 1 1 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlxA PF14282.6 PVD37822.1 - 0.019 15.0 5.5 0.019 15.0 5.5 4.6 2 1 1 4 4 4 0 FlxA-like protein DUF5082 PF16888.5 PVD37822.1 - 0.11 12.8 32.2 1.4 9.2 5.9 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 PVD37822.1 - 0.15 12.2 33.0 0.43 10.7 0.4 6.8 4 3 2 6 6 6 0 bZIP transcription factor Vac_Fusion PF02346.16 PVD37822.1 - 0.29 10.8 2.9 2.2 8.0 0.1 3.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 SNCAIP_SNCA_bd PF16700.5 PVD37822.1 - 0.39 10.5 3.3 0.45 10.3 0.6 2.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Golgin_A5 PF09787.9 PVD37822.1 - 0.55 9.6 54.6 0.37 10.2 16.6 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 DASH_Hsk3 PF08227.11 PVD37822.1 - 0.65 10.4 12.1 17 5.8 0.1 4.8 5 0 0 5 5 4 0 DASH complex subunit Hsk3 like GIT_CC PF16559.5 PVD37822.1 - 0.71 9.8 9.4 3.8 7.4 0.0 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF724 PF05266.14 PVD37822.1 - 0.91 9.3 36.0 0.22 11.3 8.8 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF724) DUF948 PF06103.11 PVD37822.1 - 1.2 9.4 10.2 0.26 11.6 0.3 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 PVD37822.1 - 1.9 8.6 63.1 1.6 8.9 4.5 4.6 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.8 PVD37822.1 - 5 7.3 13.5 4.9 7.3 1.8 4.2 2 1 1 4 4 4 0 Protein of unknown function (DUF2730) Shugoshin_N PF07558.11 PVD37822.1 - 5.2 7.0 12.9 31 4.5 0.2 5.5 6 1 1 7 7 7 0 Shugoshin N-terminal coiled-coil region Uso1_p115_C PF04871.13 PVD37822.1 - 5.3 7.4 54.7 0.58 10.5 5.3 5.2 2 1 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region BRI3BP PF14965.6 PVD37822.1 - 6.8 6.2 5.7 4.5 6.7 0.1 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DASH_Duo1 PF08651.10 PVD37822.1 - 8.1 6.3 9.2 0.27 11.1 0.7 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF5339 PF17274.2 PVD37822.1 - 9.7 7.1 7.8 12 6.8 0.5 3.5 2 1 1 3 3 2 0 Family of unknown function (DUF5339) Gelsolin PF00626.22 PVD37825.1 - 2.1e-77 255.0 0.4 4.8e-16 58.4 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 PVD37825.1 - 9.1e-16 57.6 0.2 2.4e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 Villin headpiece domain Clusterin PF01093.17 PVD37825.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin CUB PF00431.20 PVD37829.1 - 1.6e-160 524.1 10.0 2.1e-36 124.6 0.4 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 PVD37829.1 - 9e-74 247.2 0.0 1.7e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 PVD37829.1 - 2.5e-20 72.5 29.1 8.2e-10 38.8 9.1 3.2 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 PVD37829.1 - 1.1e-13 51.1 28.2 1.1e-07 31.9 7.6 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 PVD37829.1 - 2.5e-10 40.1 9.3 7e-06 25.9 1.0 3.1 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 PVD37829.1 - 1.4e-06 28.4 25.9 0.00027 21.2 4.8 3.8 2 1 1 3 3 3 2 EGF-like domain CUB_2 PF02408.20 PVD37829.1 - 5.1e-05 23.0 1.8 0.68 9.7 0.0 4.6 5 0 0 5 5 5 2 CUB-like domain Peptidase_M10 PF00413.24 PVD37829.1 - 0.00046 20.1 0.5 0.0052 16.6 0.5 2.7 1 1 0 1 1 1 1 Matrixin zinc_ribbon_2 PF13240.6 PVD37829.1 - 0.0013 18.3 2.2 0.21 11.4 0.1 4.4 4 0 0 4 4 4 1 zinc-ribbon domain EGF_3 PF12947.7 PVD37829.1 - 0.0048 17.1 33.6 0.0061 16.7 5.5 3.9 3 1 1 4 4 4 2 EGF domain zf-RING_7 PF02591.15 PVD37829.1 - 0.015 15.5 0.3 0.13 12.5 0.1 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain Reprolysin_4 PF13583.6 PVD37829.1 - 0.03 14.0 0.1 0.079 12.6 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1664 PF07889.12 PVD37829.1 - 0.066 13.3 3.4 0.12 12.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EMP70 PF02990.16 PVD37830.1 - 2.5e-162 541.2 19.5 3e-162 540.9 19.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Death PF00531.22 PVD37831.1 - 0.0017 18.4 7.2 0.0019 18.3 0.8 3.6 3 1 0 3 3 3 1 Death domain APG6_N PF17675.1 PVD37831.1 - 0.0052 17.3 31.0 0.049 14.2 12.5 3.4 2 1 1 3 3 3 2 Apg6 coiled-coil region HOOK PF05622.12 PVD37831.1 - 0.0099 14.1 21.8 0.0086 14.3 9.4 2.3 1 1 1 2 2 2 1 HOOK protein TolA_bind_tri PF16331.5 PVD37831.1 - 0.055 13.6 5.8 0.52 10.4 0.3 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 PVD37831.1 - 0.055 13.7 0.6 0.055 13.7 0.6 4.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF3450 PF11932.8 PVD37831.1 - 0.13 11.5 15.2 1.6 8.0 4.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 PVD37831.1 - 0.41 10.0 23.9 0.049 13.0 6.7 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 PVD37831.1 - 0.56 10.9 12.1 4.2 8.1 1.7 3.2 2 0 0 2 2 2 0 Initiation control protein YabA Sec34 PF04136.15 PVD37831.1 - 0.62 9.9 9.5 0.11 12.3 0.6 2.9 3 0 0 3 3 3 0 Sec34-like family DUF1664 PF07889.12 PVD37831.1 - 0.76 9.8 12.1 1.8 8.6 0.7 3.8 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 PVD37831.1 - 1.6 8.7 6.7 13 5.7 0.3 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD JAKMIP_CC3 PF16034.5 PVD37831.1 - 2.1 8.3 22.3 0.64 9.9 5.4 2.7 2 1 1 3 3 3 0 JAKMIP CC3 domain Prefoldin_2 PF01920.20 PVD37831.1 - 3.5 7.6 17.6 3.4 7.7 1.1 4.4 2 1 0 3 3 3 0 Prefoldin subunit DivIVA PF05103.13 PVD37831.1 - 9.1 6.4 13.5 12 6.0 0.3 3.8 1 1 1 3 3 3 0 DivIVA protein Pkinase PF00069.25 PVD37832.1 - 3.8e-60 203.5 0.0 4.3e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD37832.1 - 4.4e-32 111.4 0.0 4.9e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD37832.1 - 9.5e-06 24.8 0.3 1.4e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PVD37832.1 - 4e-05 23.1 0.0 6.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD37832.1 - 4.3e-05 23.0 0.1 7.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PVD37832.1 - 0.00018 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 PVD37832.1 - 0.0019 17.8 0.1 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PVD37832.1 - 0.0026 16.6 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD37832.1 - 0.027 14.4 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 PVD37833.1 - 7.5e-70 236.1 0.0 9.6e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PHD PF00628.29 PVD37834.1 - 2e-10 40.4 10.2 4e-10 39.4 10.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 PVD37834.1 - 5.9e-06 26.0 0.8 5.9e-06 26.0 0.8 2.8 2 1 0 2 2 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 PVD37834.1 - 0.00012 21.9 3.5 0.00012 21.9 3.5 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 PVD37834.1 - 0.0011 18.8 3.6 0.0011 18.8 3.6 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 PVD37834.1 - 0.0041 16.6 5.3 0.0041 16.6 5.3 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_9 PF13901.6 PVD37834.1 - 0.0066 16.5 5.3 0.016 15.2 5.3 1.6 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Borrelia_P83 PF05262.11 PVD37834.1 - 0.049 12.1 28.5 0.074 11.5 28.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PIG-X PF08320.12 PVD37834.1 - 0.07 13.0 0.7 0.13 12.1 0.7 1.4 1 0 0 1 1 1 0 PIG-X / PBN1 Cytochrome_CBB3 PF13442.6 PVD37834.1 - 0.19 12.1 0.7 0.48 10.8 0.7 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III PPP4R2 PF09184.11 PVD37834.1 - 2.9 7.4 35.9 7.5 6.1 35.9 1.6 1 0 0 1 1 1 0 PPP4R2 zf-RING_2 PF13639.6 PVD37834.1 - 4 7.8 9.4 8.3 6.8 9.4 1.5 1 1 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 PVD37834.1 - 4.4 7.5 8.6 16 5.7 8.4 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger Sin_N PF04801.13 PVD37835.1 - 8.7e-132 440.4 5.3 8.7e-132 440.4 5.3 1.9 3 0 0 3 3 3 1 Sin-like protein conserved region DUF716 PF04819.12 PVD37835.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF716) STAS_2 PF13466.6 PVD37836.1 - 0.0041 17.4 0.6 1.1 9.6 0.0 2.1 2 0 0 2 2 2 2 STAS domain RasGEF PF00617.19 PVD37838.1 - 1.5e-51 175.1 1.7 1.5e-51 175.1 1.7 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PVD37838.1 - 1.9e-14 53.7 0.1 6.3e-14 52.1 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif MutL_C PF08676.11 PVD37839.1 - 2e-29 102.2 0.0 3.9e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 PVD37839.1 - 6.8e-20 70.9 0.0 1.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PVD37839.1 - 8.7e-13 48.3 0.1 2.1e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PVD37839.1 - 5.6e-06 26.8 0.1 1.4e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ELO PF01151.18 PVD37840.1 - 5e-64 216.2 21.1 6e-64 216.0 21.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Thioredoxin PF00085.20 PVD37841.1 - 6.3e-13 48.6 0.1 2e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 PVD37841.1 - 0.0032 17.3 0.1 0.009 15.9 0.1 1.7 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 PVD37841.1 - 0.47 10.8 3.1 0.61 10.4 0.0 2.6 3 1 1 4 4 4 0 Thioredoxin-like GST_N_3 PF13417.6 PVD37842.1 - 2.4e-25 88.7 0.1 4.2e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD37842.1 - 3.2e-18 65.8 0.0 7.3e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD37842.1 - 6.5e-18 64.8 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD37842.1 - 3.9e-05 23.6 0.0 8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PVD37842.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 PVD37842.1 - 0.04 14.1 0.0 0.092 13.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD37843.1 - 8.5e-49 163.9 0.4 2.3e-23 82.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD37843.1 - 2.3e-37 127.2 0.0 2.6e-17 62.9 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD37843.1 - 8.7e-37 125.3 0.1 3.2e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PVD37843.1 - 2.3e-10 40.5 0.0 0.00096 19.3 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin GST_C_2 PF13410.6 PVD37843.1 - 8.8e-10 38.5 0.0 7.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD37843.1 - 4.3e-07 30.1 0.2 2.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD37843.1 - 3.2e-05 24.1 0.1 0.001 19.2 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PVD37843.1 - 0.0025 18.4 0.0 0.056 14.0 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PVD37844.1 - 2.7e-23 82.1 0.1 5.1e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD37844.1 - 4.8e-18 65.3 0.0 1.3e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PVD37844.1 - 1.4e-17 63.8 0.0 2.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PVD37844.1 - 2.4e-09 37.1 0.0 5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD37844.1 - 5.3e-07 29.8 0.1 8.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PVD37844.1 - 7e-07 29.4 0.1 1.4e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PVD37844.1 - 5.2e-05 23.4 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 PVD37844.1 - 0.0009 19.8 0.0 0.002 18.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ERCC4 PF02732.15 PVD37845.1 - 1.7e-09 38.1 0.4 2.3e-09 37.6 0.4 1.2 1 0 0 1 1 1 1 ERCC4 domain LPD3 PF18798.1 PVD37845.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 Herpes_UL52 PF03121.15 PVD37846.1 - 3.4e-13 49.3 0.3 3.4e-13 49.3 0.3 1.8 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase AAA PF00004.29 PVD37847.1 - 8.8e-36 123.2 0.0 2.7e-35 121.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD37847.1 - 1.1e-10 41.2 0.1 2.4e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PVD37847.1 - 2.8e-06 27.4 0.0 1.4e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD37847.1 - 1.2e-05 25.8 1.2 0.00028 21.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 PVD37847.1 - 2.5e-05 24.3 0.0 9.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 PVD37847.1 - 5.6e-05 22.6 0.0 0.22 10.9 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 PVD37847.1 - 0.00026 20.7 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PVD37847.1 - 0.00037 20.7 0.0 0.00061 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PVD37847.1 - 0.0004 20.4 0.0 0.015 15.2 0.0 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 PVD37847.1 - 0.00075 19.8 0.8 0.032 14.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PVD37847.1 - 0.0045 16.8 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PVD37847.1 - 0.005 16.2 0.3 0.011 15.1 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 PVD37847.1 - 0.0066 16.6 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 PVD37847.1 - 0.0077 15.8 0.2 1.1 8.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 PVD37847.1 - 0.0079 16.1 0.4 0.18 11.7 0.1 2.8 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 PVD37847.1 - 0.0095 16.3 0.0 0.053 13.9 0.0 2.3 2 1 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 PVD37847.1 - 0.01 15.3 0.1 0.035 13.6 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 PVD37847.1 - 0.017 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 PVD37847.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 PVD37847.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 PVD37847.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 PVD37847.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 PVD37847.1 - 0.045 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 PVD37847.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 PVD37847.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PVD37847.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 PVD37847.1 - 0.12 11.5 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 PVD37847.1 - 0.15 11.7 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 PVD37847.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PVD37848.1 - 0.00034 21.3 0.0 7.2 7.7 0.0 3.6 2 1 1 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD37848.1 - 0.0046 17.2 0.0 0.68 10.3 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 PVD37848.1 - 0.098 11.7 0.0 0.37 9.8 0.0 1.7 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 PVD37848.1 - 0.1 11.5 0.1 7.6 5.4 0.1 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MC1 PF05854.11 PVD37848.1 - 0.18 12.1 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Kinesin PF00225.23 PVD37849.1 - 5e-106 354.4 1.0 5e-106 354.4 1.0 2.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PVD37849.1 - 3.3e-24 85.5 2.9 6.2e-24 84.6 0.1 3.2 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 PVD37849.1 - 0.0048 17.0 11.1 0.0048 17.0 11.1 13.8 7 2 4 12 12 12 2 Uncharacterised protein family (UPF0242) N-terminus CC2-LZ PF16516.5 PVD37849.1 - 0.013 15.8 1.2 0.013 15.8 1.2 18.5 12 5 8 21 21 21 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ank_2 PF12796.7 PVD37850.1 - 1.9e-64 214.2 0.1 4.1e-16 59.3 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD37850.1 - 3.2e-46 155.1 2.7 1.1e-13 51.4 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37850.1 - 3.4e-37 126.0 2.3 1.2e-11 44.6 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD37850.1 - 1e-35 120.6 0.3 6.2e-07 29.6 0.1 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PVD37850.1 - 2.4e-35 116.5 0.1 4.4e-06 26.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat YfmQ PF10787.9 PVD37850.1 - 0.13 12.1 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group DUF5510 PF17629.2 PVD37851.1 - 0.37 10.8 1.7 0.79 9.7 1.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Cadherin_C_2 PF16492.5 PVD37851.1 - 0.47 11.2 0.0 0.47 11.2 0.0 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CD20 PF04103.15 PVD37851.1 - 2 8.5 27.7 49 4.0 27.8 2.3 1 1 1 2 2 2 0 CD20-like family 7tm_1 PF00001.21 PVD37853.1 - 1.4e-15 57.4 1.1 2.2e-15 56.7 1.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD37853.1 - 0.00016 21.1 1.0 0.00022 20.7 1.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD37855.1 - 7.8e-06 25.4 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UL42 PF17638.2 PVD37856.1 - 0.11 12.4 0.3 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 HCMV UL42 WD40 PF00400.32 PVD37857.1 - 2.8e-48 160.9 20.2 6e-08 33.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD37857.1 - 8.9e-08 32.3 1.0 0.74 10.1 0.0 4.7 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD37857.1 - 6.8e-05 22.8 0.1 0.00055 19.9 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PVD37857.1 - 0.0012 17.8 0.0 6.5 5.6 0.0 3.8 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PVD37857.1 - 0.034 12.7 0.0 0.13 10.8 0.1 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 PVD37857.1 - 0.054 12.1 9.4 1.4 7.5 0.2 4.4 3 1 1 5 5 5 0 Nucleoporin Nup120/160 PD40 PF07676.12 PVD37857.1 - 0.094 12.7 0.0 23 5.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Metallophos PF00149.28 PVD37858.1 - 4.8e-35 121.9 0.6 8.3e-35 121.1 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD37858.1 - 0.0043 17.5 0.2 0.0091 16.4 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 PVD37858.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain 23S_rRNA_IVP PF05635.11 PVD37858.1 - 0.071 13.4 0.8 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DUF5378 PF17349.2 PVD37858.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) EVC2_like PF12297.8 PVD37858.1 - 0.2 10.3 0.5 0.27 9.9 0.5 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Metallophos PF00149.28 PVD37859.1 - 2e-23 83.9 0.0 4.3e-16 60.0 0.0 2.6 1 1 2 3 3 3 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD37859.1 - 0.0024 18.3 0.2 0.006 17.0 0.2 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WBP-1 PF11669.8 PVD37860.1 - 0.00063 20.3 15.3 0.0017 19.0 15.3 1.9 1 1 0 1 1 1 1 WW domain-binding protein 1 RCR PF12273.8 PVD37860.1 - 0.0066 17.1 0.1 0.0088 16.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MFS_1 PF07690.16 PVD37861.1 - 1.9e-41 142.1 33.1 5.9e-25 87.9 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SPT6_acidic PF14632.6 PVD37861.1 - 0.12 13.0 4.2 0.29 11.8 4.2 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Dicty_REP PF05086.12 PVD37861.1 - 2.4 6.0 6.5 3.5 5.5 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.16 PVD37862.1 - 6.6e-23 81.2 23.1 8.9e-23 80.8 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD37862.1 - 0.012 14.5 10.9 0.02 13.8 10.9 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 PVD37862.1 - 2.3 7.0 10.2 5.2 5.8 9.5 1.7 1 1 1 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 PVD37863.1 - 4.4e-13 48.9 11.8 5.5e-13 48.6 11.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.23 PVD37864.1 - 1.6e-11 44.6 0.0 3.8e-08 33.6 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 PVD37864.1 - 0.012 14.9 0.3 0.041 13.2 0.2 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase Fructosamin_kin PF03881.14 PVD37864.1 - 0.018 14.2 0.1 0.3 10.2 0.1 2.6 2 1 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 PVD37864.1 - 0.03 13.9 0.5 0.051 13.2 0.5 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mito_carr PF00153.27 PVD37865.1 - 1.9e-57 191.1 2.5 9.1e-20 70.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PVD37865.1 - 0.077 12.1 0.4 0.6 9.2 0.4 2.3 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Tom22 PF04281.13 PVD37866.1 - 3.2e-10 39.9 0.1 4.1e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CRF PF00473.17 PVD37866.1 - 0.11 12.6 1.8 0.17 12.0 1.8 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family PH PF00169.29 PVD37867.1 - 1.9e-27 95.8 0.6 7.8e-14 52.1 0.1 3.0 2 0 0 2 2 2 2 PH domain Baculo_PEP_C PF04513.12 PVD37867.1 - 0.0019 18.3 0.3 0.0019 18.3 0.3 12.6 5 4 6 13 13 13 3 Baculovirus polyhedron envelope protein, PEP, C terminus MtrG PF04210.13 PVD37867.1 - 0.29 11.0 5.4 8 6.4 0.4 4.4 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Nif11 PF07862.11 PVD37867.1 - 2.3 8.6 7.2 15 6.0 0.1 4.7 3 0 0 3 3 3 0 Nif11 domain Cupin_8 PF13621.6 PVD37868.1 - 4.3e-40 138.0 1.9 5.6e-40 137.7 1.9 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PVD37868.1 - 1.2e-10 41.4 0.2 1.6e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DUF2046 PF09755.9 PVD37870.1 - 6.8e-151 501.7 51.5 8.3e-151 501.4 51.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) bZIP_1 PF00170.21 PVD37870.1 - 0.0016 18.5 4.6 0.0016 18.5 4.6 6.5 2 2 4 7 7 7 1 bZIP transcription factor DUF4164 PF13747.6 PVD37870.1 - 0.0025 18.0 2.8 0.0025 18.0 2.8 5.1 2 1 3 5 5 5 2 Domain of unknown function (DUF4164) Rootletin PF15035.6 PVD37870.1 - 0.0084 16.2 10.3 0.0084 16.2 10.3 3.5 1 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 PVD37870.1 - 0.015 15.7 11.7 0.015 15.7 11.7 4.8 2 1 2 4 4 4 0 Cell division protein ZapB ATG16 PF08614.11 PVD37870.1 - 0.067 13.4 55.9 0.81 9.9 5.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3828 PF12883.7 PVD37870.1 - 1.2 9.5 5.6 19 5.6 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3828) LPP PF04728.13 PVD37870.1 - 2 8.8 15.5 13 6.2 0.7 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 PVD37870.1 - 2.2 7.5 33.2 0.29 10.5 8.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 PVD37870.1 - 2.6 8.6 66.2 3 8.4 14.2 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Ank_4 PF13637.6 PVD37871.1 - 1.5e-26 92.4 0.1 2.8e-13 50.1 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD37871.1 - 7.3e-24 83.5 0.2 1.2e-10 41.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD37871.1 - 2.8e-20 72.7 0.1 3.9e-10 40.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD37871.1 - 1.2e-17 63.4 0.0 2.8e-06 27.5 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PVD37871.1 - 2.7e-17 61.1 0.1 0.00057 20.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat HTH_7 PF02796.15 PVD37871.1 - 0.13 12.4 0.0 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF5586 PF17824.1 PVD37872.1 - 5.8e-06 25.7 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) RIIa PF02197.17 PVD37872.1 - 0.00011 21.8 0.0 0.00062 19.4 0.1 2.2 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 PVD37872.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Dpy-30 motif bZIP_1 PF00170.21 PVD37873.1 - 0.0088 16.1 14.4 0.021 14.9 14.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD37873.1 - 0.62 10.6 8.8 1.5 9.4 8.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 PVD37873.1 - 0.75 9.6 2.9 1.5 8.6 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator ADAM_CR_2 PF17771.1 PVD37874.1 - 1.2e-12 48.2 4.9 1.2e-12 48.2 4.9 4.9 3 2 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin PF01421.19 PVD37874.1 - 6.7e-12 45.7 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 PVD37874.1 - 8.9e-09 35.8 0.1 2.8e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD37874.1 - 4.1e-07 30.1 0.2 9.6e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD37874.1 - 1.3e-06 28.2 0.1 3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PVD37874.1 - 2.1e-06 28.3 0.0 3.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 PVD37874.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Matrixin Eclosion PF04736.12 PVD37874.1 - 3.8 7.3 19.3 1.1 9.0 2.7 3.3 2 1 1 3 3 3 0 Eclosion hormone Alpha_kinase PF02816.18 PVD37875.1 - 3.1e-62 210.0 0.2 5.4e-62 209.2 0.2 1.4 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 PVD37875.1 - 0.0033 18.1 3.2 1.7 9.5 0.4 4.2 3 1 0 3 3 3 1 Sel1 repeat Protocadherin PF08374.11 PVD37876.1 - 0.0091 16.0 0.5 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Protocadherin EphA2_TM PF14575.6 PVD37876.1 - 0.021 15.7 0.1 0.073 14.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PVD37876.1 - 0.024 14.6 12.3 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Mucin PF01456.17 PVD37876.1 - 0.046 13.7 27.0 0.37 10.8 24.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DAP10 PF07213.11 PVD37876.1 - 0.047 13.7 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Dicty_REP PF05086.12 PVD37876.1 - 0.17 9.8 8.7 0.25 9.3 8.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CcmD PF04995.14 PVD37876.1 - 0.21 11.7 1.8 0.39 10.8 1.8 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FAM176 PF14851.6 PVD37876.1 - 0.63 9.7 0.0 0.63 9.7 0.0 2.4 3 0 0 3 3 3 0 FAM176 family FSA_C PF10479.9 PVD37876.1 - 5.4 5.0 11.4 7.6 4.5 11.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DAP10 PF07213.11 PVD37880.1 - 0.0048 16.8 1.5 0.013 15.4 1.5 1.8 1 0 0 1 1 1 1 DAP10 membrane protein Dicty_REP PF05086.12 PVD37881.1 - 5.7 4.8 6.8 7.6 4.4 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Galactosyl_T PF01762.21 PVD37885.1 - 2.6e-42 144.9 0.0 3.5e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PVD37885.1 - 0.0003 20.3 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DAP10 PF07213.11 PVD37886.1 - 0.025 14.6 0.3 0.046 13.7 0.3 1.4 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 PVD37886.1 - 0.038 14.9 0.0 0.086 13.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 PVD37886.1 - 0.12 12.1 0.2 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 FAM176 family CcmD PF04995.14 PVD37886.1 - 0.19 11.8 1.3 0.36 11.0 1.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ADD_DNMT3 PF17980.1 PVD37887.1 - 4.3e-13 49.0 2.7 4.3e-13 49.0 2.7 3.7 4 0 0 4 4 4 1 Cysteine rich ADD domain in DNMT3 DNA_methylase PF00145.17 PVD37887.1 - 4.6e-12 45.9 0.0 3.9e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase PWWP PF00855.17 PVD37887.1 - 0.0022 18.3 0.1 0.0085 16.5 0.0 2.0 2 0 0 2 2 2 1 PWWP domain CRAL_TRIO PF00650.20 PVD37888.1 - 4.3e-38 130.5 0.0 7.4e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain PRELI PF04707.14 PVD37888.1 - 4.7e-17 62.2 0.0 1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO_N PF03765.15 PVD37888.1 - 2.7e-07 30.7 0.0 6.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PMP22_Claudin PF00822.20 PVD37889.1 - 0.27 11.1 3.7 0.45 10.4 3.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4714 PF15833.5 PVD37889.1 - 0.61 10.0 3.4 0.64 10.0 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4714) Colicin_V PF02674.16 PVD37890.1 - 0.027 14.5 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein DNA_pol_phi PF04931.13 PVD37892.1 - 7.3 4.5 12.2 8.5 4.3 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Stork_head PF10264.9 PVD37895.1 - 8.9e-25 86.7 0.0 1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Clat_adaptor_s PF01217.20 PVD37895.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Gelsolin PF00626.22 PVD37897.1 - 8.7e-46 153.7 2.0 1.2e-12 47.6 0.0 5.7 5 0 0 5 5 5 5 Gelsolin repeat LRR_8 PF13855.6 PVD37897.1 - 7.8e-23 80.0 36.3 7.3e-07 28.9 3.2 5.5 3 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PVD37897.1 - 7.3e-18 64.4 45.2 7.2e-07 29.4 1.6 7.4 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD37897.1 - 0.21 12.3 36.0 3.1 8.7 0.3 9.4 8 1 0 8 8 8 0 Leucine Rich Repeat NTF2 PF02136.20 PVD37898.1 - 8.2e-26 90.9 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 PVD37898.1 - 3.4e-14 52.4 0.0 5.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD37898.1 - 1.8e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif PDEase_I PF00233.19 PVD37899.1 - 2.2e-65 220.7 4.8 2.2e-65 220.7 4.8 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PVD37899.1 - 1.4e-33 116.4 0.0 5.6e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PVD37899.1 - 2.3e-17 63.6 0.0 2.7e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 PVD37899.1 - 0.00011 22.5 0.0 0.21 11.9 0.0 3.3 3 0 0 3 3 3 1 GAF domain SpoVT_C PF15714.5 PVD37899.1 - 0.0086 16.1 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor HD PF01966.22 PVD37899.1 - 0.026 14.7 0.0 0.092 13.0 0.0 1.9 1 0 0 1 1 1 0 HD domain dCache_1 PF02743.18 PVD37899.1 - 0.028 14.2 0.2 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Cache domain H_kinase_N PF12282.8 PVD37899.1 - 0.1 12.5 0.0 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Signal transduction histidine kinase SPARC_Ca_bdg PF10591.9 PVD37900.1 - 2.8e-28 98.5 6.7 1.5e-27 96.2 2.6 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 PVD37900.1 - 1.9e-05 24.7 5.9 1.9e-05 24.7 5.9 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD37900.1 - 0.0026 17.7 1.4 0.0026 17.7 1.4 2.3 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 PVD37900.1 - 0.032 14.4 1.9 0.032 14.4 1.9 2.3 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain Plasmod_Pvs28 PF06247.11 PVD37900.1 - 0.033 14.5 4.4 0.033 14.5 4.4 2.4 2 0 0 2 2 2 0 Pvs28 EGF domain IF4E PF01652.18 PVD37901.1 - 3.2e-55 186.3 0.1 6.1e-55 185.4 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.22 PVD37901.1 - 8.5e-14 51.1 0.5 9.4e-06 25.4 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha PF03896.16 PVD37901.1 - 3.1 6.9 14.8 0.24 10.6 2.6 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ApbA PF02558.16 PVD37901.1 - 8.2 6.1 7.3 0.86 9.2 1.2 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RRM_1 PF00076.22 PVD37902.1 - 4.6e-37 125.7 1.9 2.5e-13 49.6 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD37902.1 - 0.0044 17.1 0.1 2.4 8.4 0.0 3.8 3 1 0 3 3 3 1 RNA recognition motif CDC45 PF02724.14 PVD37902.1 - 0.0096 14.3 4.6 0.013 13.9 4.6 1.3 1 0 0 1 1 1 1 CDC45-like protein PRE_C2HC PF07530.11 PVD37902.1 - 0.04 14.0 0.1 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Associated with zinc fingers PHM7_cyt PF14703.6 PVD37902.1 - 0.044 14.0 1.9 0.52 10.5 0.0 2.8 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DnaI_N PF07319.11 PVD37902.1 - 0.052 14.2 1.3 13 6.5 0.5 2.8 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus RRM_occluded PF16842.5 PVD37902.1 - 0.08 12.8 0.2 8 6.4 0.0 3.6 5 0 0 5 5 5 0 Occluded RNA-recognition motif SecD-TM1 PF13721.6 PVD37902.1 - 0.13 12.7 0.5 6.6 7.3 0.2 2.5 2 0 0 2 2 2 0 SecD export protein N-terminal TM region eIF-3c_N PF05470.12 PVD37902.1 - 0.59 8.4 8.3 0.84 7.9 8.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF913 PF06025.12 PVD37902.1 - 0.9 8.4 4.6 1.8 7.5 4.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ANF_receptor PF01094.28 PVD37903.1 - 1e-61 209.0 0.0 1.4e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD37903.1 - 4.6e-44 150.9 22.7 8.5e-44 150.0 22.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Ni_hydr_CYTB PF01292.20 PVD37903.1 - 0.014 15.0 3.0 0.027 14.1 0.4 2.6 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF5420 PF17457.2 PVD37903.1 - 0.078 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) UL41A PF17591.2 PVD37903.1 - 0.1 12.7 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 Herpesvirus UL41A Strabismus PF06638.11 PVD37903.1 - 6.3 5.3 8.5 11 4.5 8.5 1.3 1 0 0 1 1 1 0 Strabismus protein ANF_receptor PF01094.28 PVD37904.1 - 4.7e-57 193.7 1.4 6.8e-57 193.2 1.4 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 PVD37904.1 - 8e-13 48.8 0.9 3.2e-12 46.8 0.9 1.8 1 1 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 PVD37904.1 - 1.6e-07 31.3 6.5 1.7e-07 31.2 5.1 1.7 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DAGK_cat PF00781.24 PVD37904.1 - 0.83 9.3 3.5 37 4.0 0.0 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Claudin_2 PF13903.6 PVD37905.1 - 2.5e-15 56.7 4.3 3.1e-15 56.4 4.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD37905.1 - 1.3e-06 28.3 6.1 3.4e-06 27.0 6.1 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 PVD37905.1 - 0.00053 19.7 5.2 0.00078 19.1 5.2 1.3 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 PVD37905.1 - 0.0032 17.3 9.2 0.0051 16.7 9.2 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF2721 PF11026.8 PVD37905.1 - 0.028 14.3 2.6 0.028 14.3 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Trp_oprn_chp PF09534.10 PVD37905.1 - 0.052 13.3 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CrgA PF06781.12 PVD37905.1 - 0.17 12.0 1.4 0.18 11.9 0.3 1.6 2 0 0 2 2 2 0 Cell division protein CrgA Mfp-3 PF04202.13 PVD37905.1 - 1.2 9.5 12.6 0.3 11.5 5.8 2.3 2 0 0 2 2 2 0 Foot protein 3 FAM176 PF14851.6 PVD37906.1 - 0.12 12.1 1.8 2.9 7.6 0.1 2.1 2 0 0 2 2 2 0 FAM176 family PMP22_Claudin PF00822.20 PVD37907.1 - 0.0046 16.9 3.0 0.0065 16.4 3.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD37907.1 - 0.007 16.1 1.6 0.0076 16.0 0.9 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD37908.1 - 0.0015 18.5 0.2 0.0021 17.9 0.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family CEND1 PF15677.5 PVD37908.1 - 0.0018 18.8 0.5 0.0025 18.4 0.5 1.1 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 Claudin_2 PF13903.6 PVD37908.1 - 0.0019 18.0 0.7 0.003 17.3 0.1 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_2 PF13903.6 PVD37909.1 - 1.2e-12 48.0 1.7 1.5e-12 47.7 1.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD37909.1 - 1.8e-10 40.9 2.0 2.4e-10 40.5 2.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD37909.1 - 0.00058 19.8 0.5 0.00077 19.4 0.5 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 PVD37909.1 - 0.016 15.0 1.2 0.022 14.6 1.2 1.2 1 0 0 1 1 1 0 Amastin surface glycoprotein Clc-like PF07062.12 PVD37909.1 - 0.019 14.4 2.7 0.025 14.0 2.7 1.1 1 0 0 1 1 1 0 Clc-like DuoxA PF10204.9 PVD37909.1 - 0.028 13.5 2.1 0.038 13.0 2.1 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor L_HMGIC_fpl PF10242.9 PVD37909.1 - 0.48 10.6 5.0 0.83 9.8 5.0 1.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein SUR7 PF06687.12 PVD37909.1 - 0.81 9.3 4.9 1.5 8.4 5.0 1.4 1 1 0 1 1 1 0 SUR7/PalI family MRAP PF15183.6 PVD37910.1 - 0.0054 16.7 0.2 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family COG2 PF06148.11 PVD37910.1 - 0.0059 16.7 0.9 0.01 15.9 0.9 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Shisa PF13908.6 PVD37910.1 - 0.0073 16.6 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tweety PF04906.13 PVD37910.1 - 0.0087 14.8 1.6 0.012 14.3 1.6 1.1 1 0 0 1 1 1 1 Tweety DUF2524 PF10732.9 PVD37910.1 - 0.011 16.1 4.4 0.03 14.6 4.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2524) OmpH PF03938.14 PVD37910.1 - 0.013 15.8 0.8 0.021 15.2 0.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Saf_2TM PF18303.1 PVD37910.1 - 0.023 14.3 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain TMEM154 PF15102.6 PVD37910.1 - 0.026 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF3584 PF12128.8 PVD37910.1 - 0.038 11.5 1.7 0.05 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TraF_2 PF13729.6 PVD37910.1 - 0.041 13.3 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Orf78 PF06024.12 PVD37910.1 - 0.054 13.8 0.4 0.054 13.8 0.4 1.5 2 0 0 2 2 1 0 Orf78 (ac78) PAG PF15347.6 PVD37910.1 - 0.073 12.1 0.7 0.12 11.3 0.7 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched MLANA PF14991.6 PVD37910.1 - 0.1 12.9 0.9 0.18 12.1 0.6 1.6 1 1 0 1 1 1 0 Protein melan-A ECSCR PF15820.5 PVD37910.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF2207 PF09972.9 PVD37910.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SIT PF15330.6 PVD37910.1 - 0.17 12.4 0.3 0.17 12.4 0.3 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT APG6_N PF17675.1 PVD37910.1 - 0.2 12.1 6.5 0.4 11.2 6.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region LRR19-TM PF15176.6 PVD37910.1 - 0.27 11.3 1.8 0.43 10.6 1.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain KfrA_N PF11740.8 PVD37910.1 - 4 8.1 6.5 7.3 7.3 6.5 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HemY_N PF07219.13 PVD37910.1 - 5.7 7.2 5.5 3.3 8.0 1.4 2.1 1 1 1 2 2 2 0 HemY protein N-terminus Prominin PF05478.11 PVD37914.1 - 0.019 12.9 14.0 0.025 12.6 14.0 1.2 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 PVD37914.1 - 0.099 12.7 18.0 0.58 10.2 18.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 PVD37914.1 - 0.12 12.3 16.8 0.18 11.7 2.4 3.1 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Apolipoprotein PF01442.18 PVD37914.1 - 0.39 10.6 17.5 0.079 12.8 11.7 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain GPHR_N PF12537.8 PVD37914.1 - 0.48 10.6 12.1 1.3 9.2 0.4 3.6 3 1 0 4 4 4 0 The Golgi pH Regulator (GPHR) Family N-terminal Collagen_mid PF15984.5 PVD37914.1 - 0.7 9.6 3.9 1.9 8.2 3.9 1.6 1 1 0 1 1 1 0 Bacterial collagen, middle region Phasin PF05597.11 PVD37914.1 - 0.82 9.7 12.9 0.22 11.5 7.9 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) H-kinase_dim PF02895.14 PVD37914.1 - 1.9 8.9 10.6 1.6 9.2 2.3 3.2 1 1 2 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF883 PF05957.13 PVD37914.1 - 2.8 8.6 8.7 1.8 9.2 1.4 3.1 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF883) FAM25 PF15825.5 PVD37914.1 - 3.2 8.2 8.4 12 6.3 0.5 3.2 2 1 1 3 3 3 0 FAM25 family PIN_8 PF18476.1 PVD37914.1 - 4 7.2 14.2 0.8 9.5 10.5 1.6 2 0 0 2 2 2 0 PIN like domain DUF2935 PF11155.8 PVD37914.1 - 4.1 7.7 10.2 1.4 9.3 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) TRPM_tetra PF16519.5 PVD37914.1 - 4.7 7.4 11.4 10 6.3 0.4 3.3 1 1 2 3 3 3 0 Tetramerisation domain of TRPM YtxH PF12732.7 PVD37914.1 - 4.9 7.7 10.4 22 5.7 6.4 3.0 2 1 0 2 2 2 0 YtxH-like protein DUF3810 PF12725.7 PVD37914.1 - 5.2 6.3 10.2 13 5.0 9.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) FlxA PF14282.6 PVD37914.1 - 6.6 6.8 27.8 0.25 11.3 4.9 3.5 2 1 1 3 3 3 0 FlxA-like protein FlgN PF05130.12 PVD37914.1 - 9.2 6.8 25.1 2.8 8.5 10.5 3.1 2 1 1 3 3 3 0 FlgN protein Ycf70 PF17382.2 PVD37915.1 - 0.083 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Ycf70-like Folate_rec PF03024.14 PVD37916.1 - 1.2e-16 61.0 8.9 1.2e-16 61.0 8.9 1.6 2 0 0 2 2 2 1 Folate receptor family Fz PF01392.22 PVD37916.1 - 0.42 11.3 6.3 1 10.0 6.3 1.7 1 0 0 1 1 1 0 Fz domain SH3_1 PF00018.28 PVD37917.1 - 5.3e-36 122.0 2.6 3.5e-17 61.7 0.2 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 PVD37917.1 - 1.3e-30 105.0 0.3 6.5e-16 57.9 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PVD37917.1 - 4.9e-24 83.8 0.1 2.2e-11 43.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 PVD37917.1 - 1.9e-23 82.4 0.0 3.6e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 PVD37917.1 - 7.5e-07 29.3 1.5 4.4e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.6 PVD37917.1 - 0.00055 20.3 0.1 0.0036 17.7 0.0 2.2 2 1 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.6 PVD37917.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_10 PF17902.1 PVD37917.1 - 0.1 12.6 0.1 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 SH3 domain PDZ PF00595.24 PVD37918.1 - 1.5e-12 47.7 0.0 3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD37918.1 - 1.1e-05 25.1 0.2 2.6e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD37918.1 - 0.00035 20.9 0.0 0.00078 19.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain BK_channel_a PF03493.18 PVD37919.1 - 1.8e-35 121.0 0.0 5.8e-35 119.4 0.0 1.9 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 PVD37919.1 - 6.7e-18 64.8 19.6 1.5e-17 63.6 19.6 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PVD37919.1 - 2.2e-15 56.4 3.6 2.2e-15 56.4 3.6 3.6 4 0 0 4 4 4 1 Ion channel TrkA_N PF02254.18 PVD37919.1 - 8.5e-05 22.8 0.2 0.0022 18.2 0.1 2.7 3 0 0 3 3 3 1 TrkA-N domain Lig_chan PF00060.26 PVD37919.1 - 0.14 12.0 4.3 0.14 12.0 0.2 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel RRS1 PF04939.12 PVD37920.1 - 3.4e-56 189.6 10.3 3.4e-56 189.6 10.3 1.9 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) FAM184 PF15665.5 PVD37920.1 - 0.026 14.3 10.0 0.038 13.8 4.1 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF410 PF04190.13 PVD37921.1 - 5.2e-81 272.2 0.0 6.8e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DEAD PF00270.29 PVD37922.1 - 1.2e-44 152.2 0.0 3.6e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37922.1 - 3.3e-30 104.7 0.0 1.2e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD37922.1 - 0.00029 20.9 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNase_PH PF01138.21 PVD37923.1 - 5e-19 69.1 0.1 9.2e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DEAD PF00270.29 PVD37924.1 - 1.2e-40 139.2 0.1 1.7e-39 135.4 0.0 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PVD37924.1 - 1.1e-29 103.0 0.0 3.5e-29 101.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PVD37924.1 - 8.5e-05 22.6 0.0 0.078 13.0 0.0 3.1 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD37924.1 - 0.024 15.0 0.1 1.3 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain RhoGAP PF00620.27 PVD37925.1 - 1.3e-44 151.7 0.5 2.7e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.18 PVD37925.1 - 1.1e-39 136.5 2.3 1.8e-39 135.8 2.3 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 PVD37925.1 - 0.015 14.4 2.0 0.033 13.3 2.0 1.7 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking LepA_C PF06421.12 PVD37926.1 - 4.2e-43 145.9 0.1 7.4e-43 145.1 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PVD37926.1 - 9.7e-22 76.8 0.0 2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 PVD37926.1 - 2.5e-18 66.3 0.0 2.1e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PVD37926.1 - 3.4e-09 37.0 0.0 9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PVD37926.1 - 0.0042 16.9 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 PVD37926.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 PVD37926.1 - 0.012 15.2 0.1 0.19 11.3 0.0 2.2 1 1 1 2 2 2 0 Ras family FeoB_N PF02421.18 PVD37926.1 - 0.1 12.1 0.1 0.26 10.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PVD37926.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3099 PF11298.8 PVD37927.1 - 0.067 13.3 0.6 0.067 13.3 0.6 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3099) DUF3925 PF13063.6 PVD37927.1 - 0.15 12.3 0.1 0.15 12.3 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3925) Glyco_hydro_1 PF00232.18 PVD37928.1 - 0.087 11.2 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Nudc_N PF14050.6 PVD37930.1 - 6e-24 83.8 0.1 1.2e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 PVD37930.1 - 1.6e-13 51.4 0.2 3.7e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 CS domain IF2_assoc PF08364.11 PVD37930.1 - 0.17 12.2 1.2 0.42 10.9 1.2 1.6 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region RUN PF02759.19 PVD37931.1 - 3e-19 69.3 0.2 1.2e-18 67.4 0.1 2.0 2 0 0 2 2 2 1 RUN domain PX PF00787.24 PVD37931.1 - 1.9e-15 56.8 0.4 1.9e-15 56.8 0.4 2.3 3 0 0 3 3 3 1 PX domain Phage_term_sma PF07141.11 PVD37931.1 - 0.078 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Ribosomal_L16 PF00252.18 PVD37932.1 - 2.1e-21 76.3 0.1 3e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HMG_box PF00505.19 PVD37935.1 - 2.6e-21 75.8 0.9 5e-21 74.9 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD37935.1 - 5.2e-08 33.4 0.8 5.2e-08 33.4 0.8 1.9 2 0 0 2 2 2 1 HMG-box domain CTNNB1_binding PF08347.11 PVD37935.1 - 0.00047 20.4 14.8 0.00047 20.4 14.8 3.5 3 2 0 3 3 3 1 N-terminal CTNNB1 binding Pyrophosphatase PF00719.19 PVD37936.1 - 5e-45 153.2 0.1 7.2e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Laminin_G_2 PF02210.24 PVD37937.1 - 6.4e-99 327.3 14.6 1.2e-20 74.3 0.0 9.1 9 0 0 9 9 9 7 Laminin G domain Laminin_G_1 PF00054.23 PVD37937.1 - 1.1e-69 232.8 0.1 1.7e-15 57.4 0.0 7.8 7 0 0 7 7 7 5 Laminin G domain Laminin_G_3 PF13385.6 PVD37937.1 - 2.8e-43 147.7 23.8 4.1e-12 46.5 0.0 8.3 8 0 0 8 8 8 7 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 PVD37937.1 - 1.3e-16 60.7 0.9 1.9e-08 34.8 0.2 4.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 PVD37937.1 - 2.5e-06 26.5 0.4 0.0019 16.9 0.0 3.6 1 1 3 4 4 4 1 Nucleoporin Nup120/160 DUF1080 PF06439.11 PVD37937.1 - 4.7e-05 23.6 5.9 0.6 10.2 0.0 5.9 6 1 0 6 6 6 2 Domain of Unknown Function (DUF1080) ANAPC4_WD40 PF12894.7 PVD37937.1 - 0.0001 22.5 0.1 0.0046 17.2 0.2 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain EGF PF00008.27 PVD37937.1 - 0.00034 20.9 20.2 0.044 14.1 4.2 3.3 3 0 0 3 3 3 2 EGF-like domain WD40_like PF17005.5 PVD37937.1 - 0.092 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Nucleoporin_N PF08801.11 PVD37937.1 - 0.2 10.4 0.1 9.7 4.8 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like hEGF PF12661.7 PVD37937.1 - 0.73 10.6 22.3 0.94 10.2 4.8 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 PVD37937.1 - 6.5 7.2 23.9 0.21 12.0 6.5 2.8 2 0 0 2 2 2 0 EGF-like domain Plasmod_Pvs28 PF06247.11 PVD37937.1 - 6.5 7.1 7.0 18 5.8 1.9 2.5 2 0 0 2 2 2 0 Pvs28 EGF domain Laminin_G_3 PF13385.6 PVD37938.1 - 1e-17 64.7 1.4 2.5e-12 47.2 0.2 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PVD37938.1 - 0.0077 16.8 0.2 0.029 14.9 0.1 1.9 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 PVD37938.1 - 0.044 14.0 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Pentaxin PF00354.17 PVD37938.1 - 0.21 11.3 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 Pentaxin family Laminin_G_2 PF02210.24 PVD37939.1 - 1.6e-21 77.2 0.0 2.3e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 PVD37939.1 - 7.3e-18 65.0 0.0 1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 PVD37939.1 - 0.0078 16.4 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily VHL PF01847.16 PVD37939.1 - 0.2 11.6 0.2 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 VHL beta domain SLX9 PF15341.6 PVD37940.1 - 5e-12 46.4 12.2 5e-12 46.4 12.2 2.7 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 CDC24_OB2 PF17245.2 PVD37940.1 - 0.0087 16.6 0.2 0.018 15.6 0.2 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 DUF4485 PF14846.6 PVD37940.1 - 0.083 12.9 1.4 0.19 11.8 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) MT0933_antitox PF14013.6 PVD37941.1 - 3.8e-06 27.1 12.1 0.028 14.7 0.3 4.3 1 1 3 4 4 4 4 MT0933-like antitoxin protein CelTOS PF18659.1 PVD37941.1 - 0.00074 19.9 5.4 0.28 11.6 5.4 2.4 1 1 0 1 1 1 1 Cell-traversal protein for ookinetes and sporozoites SseC PF04888.12 PVD37941.1 - 0.00075 19.2 3.7 0.00099 18.8 3.7 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF3334 PF11813.8 PVD37941.1 - 0.00078 19.2 9.4 0.058 13.1 1.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3334) DUF445 PF04286.12 PVD37941.1 - 0.013 15.3 0.1 0.015 15.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TMEM65 PF10507.9 PVD37941.1 - 0.018 14.9 1.7 1.3 9.0 0.4 2.2 1 1 1 2 2 2 0 Transmembrane protein 65 Peptidase_M22 PF00814.25 PVD37941.1 - 0.026 14.2 0.9 0.72 9.5 0.8 2.6 1 1 1 2 2 2 0 Glycoprotease family NAAA-beta PF15508.6 PVD37941.1 - 0.098 13.0 0.1 6.4 7.2 0.0 2.9 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1048 PF06304.11 PVD37941.1 - 0.89 10.0 9.0 2.9 8.4 1.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1048) Shisa PF13908.6 PVD37942.1 - 0.02 15.1 0.1 0.13 12.5 0.0 2.0 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Protocadherin PF08374.11 PVD37942.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protocadherin Orthoreo_P10 PF07204.11 PVD37942.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 PTB PF08416.13 PVD37943.1 - 2.7e-36 124.6 0.0 5.4e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.9 PVD37943.1 - 5.4e-30 103.9 0.0 1.2e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.24 PVD37943.1 - 5e-10 39.3 0.0 2.8e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 SH2 domain DSPc PF00782.20 PVD37943.1 - 0.011 15.5 0.0 0.053 13.3 0.0 2.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain C1_1 PF00130.22 PVD37944.1 - 9.2e-09 35.1 12.4 9.2e-09 35.1 12.4 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 PVD37944.1 - 0.0074 16.4 5.5 0.013 15.6 5.5 1.3 1 0 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 PVD37944.1 - 0.23 11.1 9.2 0.42 10.3 9.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad10 PF03834.14 PVD37947.1 - 1.5e-48 163.5 0.0 2.6e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 PVD37947.1 - 2.9e-05 24.6 0.0 0.00016 22.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 PVD37947.1 - 8.5e-05 22.6 0.0 0.00026 21.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.25 PVD37947.1 - 0.049 14.1 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF1365 PF07103.11 PVD37947.1 - 0.097 12.3 0.7 0.14 11.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1365) PRKCSH_1 PF13015.6 PVD37948.1 - 2.6e-13 49.9 0.0 4.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PVD37948.1 - 7.1e-07 30.1 1.0 7.1e-07 30.1 1.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Surfac_D-trimer PF09006.11 PVD37948.1 - 0.017 15.0 0.2 0.086 12.8 0.2 2.3 1 1 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DMAP_binding PF06464.11 PVD37948.1 - 0.28 12.0 4.4 0.56 11.0 4.4 1.4 1 0 0 1 1 1 0 DMAP1-binding Domain FapA PF03961.13 PVD37948.1 - 0.43 9.1 2.6 0.58 8.7 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribo_biogen_C PF04034.13 PVD37949.1 - 9e-50 167.7 0.0 1.4e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 PVD37949.1 - 4.3e-13 48.8 0.0 9.8e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI tRNA_anti-codon PF01336.25 PVD37949.1 - 0.046 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Presenilin PF01080.17 PVD37949.1 - 5.6 5.6 4.2 7.9 5.1 4.2 1.1 1 0 0 1 1 1 0 Presenilin Arm PF00514.23 PVD37950.1 - 2.1e-42 141.9 29.2 1.3e-07 31.3 0.1 10.9 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PVD37950.1 - 5.1e-07 28.6 7.5 4.8e-06 25.4 2.0 2.9 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 PVD37950.1 - 5.4e-06 26.7 9.3 0.00014 22.2 0.8 5.0 4 1 1 5 5 5 2 HEAT repeats KAP PF05804.12 PVD37950.1 - 0.00013 20.3 5.9 0.035 12.3 0.4 2.6 1 1 3 4 4 4 3 Kinesin-associated protein (KAP) HEAT PF02985.22 PVD37950.1 - 0.00014 21.8 9.9 1.1 9.7 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 PVD37950.1 - 0.0005 20.1 4.7 0.019 15.0 0.4 3.2 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 PVD37950.1 - 0.001 18.6 4.0 0.071 12.6 0.3 3.8 4 1 2 6 6 6 1 Armadillo-like HEAT_EZ PF13513.6 PVD37950.1 - 0.0011 19.4 9.7 2.4 8.8 0.1 5.7 4 1 1 5 5 5 1 HEAT-like repeat Atx10homo_assoc PF09759.9 PVD37950.1 - 0.0035 17.3 3.0 0.021 14.9 0.1 3.2 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Pes-10 PF07149.11 PVD37950.1 - 0.0045 16.1 0.5 1.7 7.6 0.0 2.4 2 1 0 2 2 2 2 Pes-10 RasGEF_N_2 PF14663.6 PVD37950.1 - 0.011 16.1 8.7 5.8 7.4 0.0 4.8 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.9 PVD37950.1 - 0.017 13.6 4.1 1.4 7.3 0.2 2.5 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF3731 PF12531.8 PVD37950.1 - 0.033 14.0 0.1 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 DNA-K related protein Glyco_hydro_18 PF00704.28 PVD37954.1 - 0.00021 21.1 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 PVD37955.1 - 2.8e-36 125.9 0.0 3.2e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 KASH PF10541.9 PVD37956.1 - 0.41 11.0 2.5 9.1 6.6 0.2 3.2 3 0 0 3 3 3 0 Nuclear envelope localisation domain SSF PF00474.17 PVD37957.1 - 1.4e-25 90.0 34.7 1.4e-25 90.0 32.8 1.9 2 1 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 PVD37958.1 - 7.8e-32 110.6 32.2 1.2e-31 110.0 30.9 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 PVD37960.1 - 8e-10 38.1 13.8 1.1e-09 37.7 13.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family YwiC PF14256.6 PVD37960.1 - 0.00047 20.5 11.0 0.014 15.7 0.5 3.1 2 1 1 3 3 3 2 YwiC-like protein SSF PF00474.17 PVD37961.1 - 1.5e-30 106.4 25.9 1.1e-25 90.3 15.6 2.2 1 1 1 2 2 2 2 Sodium:solute symporter family Mito_carr PF00153.27 PVD37962.1 - 4.5e-56 186.8 3.4 4.1e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PVD37962.1 - 0.00014 21.1 0.1 0.1 11.7 0.0 3.2 2 1 1 3 3 3 2 Gammaproteobacterial serine protease HMG_box PF00505.19 PVD37963.1 - 4.4e-23 81.5 44.7 4.3e-12 46.3 2.6 6.2 5 2 1 6 6 6 4 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD37963.1 - 2.4e-17 63.3 35.5 7.5e-08 32.9 0.8 6.4 4 1 1 5 5 5 4 HMG-box domain CHDNT PF08073.12 PVD37963.1 - 0.024 14.6 0.0 0.1 12.6 0.0 2.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain RXLR PF16810.5 PVD37963.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.6 2 1 1 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity DUF3417 PF11897.8 PVD37963.1 - 0.24 11.9 8.1 0.12 12.8 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) HMG_box PF00505.19 PVD37964.1 - 1.5e-20 73.3 22.4 2.2e-12 47.2 1.0 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PVD37964.1 - 6.2e-17 62.0 17.8 3.9e-09 37.0 0.5 3.3 3 1 0 3 3 3 2 HMG-box domain Endonuc_Holl PF10107.9 PVD37964.1 - 0.87 9.4 10.8 0.68 9.8 1.3 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Peptidase_M14 PF00246.24 PVD37965.1 - 7.2e-66 222.9 0.0 2.7e-65 221.0 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 PVD37965.1 - 0.0062 15.6 0.2 0.028 13.5 0.2 2.1 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 PVD37965.1 - 0.0085 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) CarboxypepD_reg PF13620.6 PVD37966.1 - 4.4e-11 42.9 0.1 6e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PVD37966.1 - 4.4e-05 23.4 0.9 0.00015 21.7 0.9 1.9 1 1 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 PVD37966.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 PEGA domain RPEL PF02755.15 PVD37968.1 - 4.3e-17 61.2 15.6 2e-07 30.5 3.1 4.0 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.27 PVD37968.1 - 6.7e-13 48.1 0.2 2e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 SAP domain Pkinase PF00069.25 PVD37969.1 - 1.1e-36 126.6 0.1 2.1e-24 86.3 0.2 2.4 1 1 1 2 2 2 2 Protein kinase domain PH_3 PF14593.6 PVD37969.1 - 4.5e-21 74.9 0.1 1.7e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 PVD37969.1 - 5.5e-18 65.2 0.1 1.2e-13 51.0 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PVD37969.1 - 0.056 12.7 0.0 6.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like BTB_2 PF02214.22 PVD37970.1 - 1.1e-20 73.8 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RTX PF02382.15 PVD37970.1 - 0.022 14.5 0.2 0.03 14.0 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein BTB PF00651.31 PVD37970.1 - 0.094 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Mt_ATP-synt_D PF05873.12 PVD37971.1 - 5.4e-50 169.2 6.0 6.1e-50 169.1 6.0 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4660 PF15559.6 PVD37971.1 - 0.011 16.1 0.5 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) TMF_TATA_bd PF12325.8 PVD37972.1 - 3.3e-30 104.7 13.6 3.3e-30 104.7 13.6 8.7 4 1 4 9 9 9 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 PVD37972.1 - 3.3e-20 71.8 17.2 3.3e-20 71.8 17.2 10.0 5 3 5 11 11 11 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 PVD37972.1 - 6.6e-05 23.2 6.3 6.6e-05 23.2 6.3 7.4 4 1 2 7 7 7 2 Autophagy protein 16 (ATG16) Chorion_3 PF05387.11 PVD37973.1 - 3.6 7.2 4.8 4.3 6.9 4.8 1.2 1 0 0 1 1 1 0 Chorion family 3 Ig_3 PF13927.6 PVD37974.1 - 2.7e-09 37.5 0.1 7e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD37974.1 - 9.9e-09 35.4 0.1 2.2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 PVD37974.1 - 6.8e-07 29.3 0.0 1.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 PVD37974.1 - 3.5e-06 27.1 0.0 6.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 PVD37974.1 - 0.098 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Sec23_trunk PF04811.15 PVD37976.1 - 4.5e-53 180.3 0.5 1.8e-33 116.1 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PVD37976.1 - 4.8e-20 71.3 2.1 1e-19 70.2 2.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PVD37976.1 - 9.6e-15 54.4 4.5 2e-14 53.3 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PVD37976.1 - 1.3e-12 48.3 0.0 2.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 PVD37976.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Arf PF00025.21 PVD37977.1 - 3.4e-74 248.0 0.0 3.9e-61 205.5 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 PVD37977.1 - 8.1e-13 48.2 0.0 2.4e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD37977.1 - 2.1e-12 46.9 1.2 1e-07 31.5 0.0 3.3 1 1 1 3 3 3 3 G-protein alpha subunit Roc PF08477.13 PVD37977.1 - 2.3e-10 40.7 0.0 4.2e-07 30.2 0.0 2.5 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PVD37977.1 - 1.5e-09 37.9 0.0 1.1e-05 25.5 0.0 2.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase Ras PF00071.22 PVD37977.1 - 5.8e-09 35.8 0.0 2.1e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 PVD37977.1 - 1.3e-06 27.9 0.0 0.00037 19.9 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region cobW PF02492.19 PVD37977.1 - 0.00068 19.3 0.3 0.21 11.1 0.0 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PVD37977.1 - 0.00076 19.2 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.17 PVD37977.1 - 0.0052 16.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase ABC_tran PF00005.27 PVD37977.1 - 0.01 16.3 0.8 3.4 8.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter MobB PF03205.14 PVD37977.1 - 0.03 14.2 0.3 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 PVD37977.1 - 0.052 13.1 0.1 6.3 6.3 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 PVD37977.1 - 0.13 12.0 0.9 9.9 6.0 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PEPCK_ATP PF01293.20 PVD37977.1 - 1.7 7.2 3.3 15 4.1 0.4 2.0 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxykinase zf-C2H2 PF00096.26 PVD37979.1 - 8e-08 32.3 47.9 0.00056 20.2 4.0 7.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD37979.1 - 1.9e-06 28.2 45.1 0.028 15.3 2.7 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD37979.1 - 0.022 15.2 2.2 0.022 15.2 2.2 8.6 12 0 0 12 12 12 0 Zinc-finger double domain O-FucT PF10250.9 PVD37980.1 - 1.7e-70 238.4 0.1 2.2e-70 238.0 0.1 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SGS PF05002.15 PVD37980.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 SGS domain 7tm_1 PF00001.21 PVD37981.1 - 1.9e-21 76.5 11.7 2.9e-21 76.0 11.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD37981.1 - 8.5e-08 32.1 13.3 1.1e-07 31.7 13.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD37981.1 - 0.00083 19.2 7.3 0.0012 18.7 7.3 1.2 1 0 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 PVD37981.1 - 0.024 14.6 10.5 0.037 14.0 10.5 1.4 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 PVD37982.1 - 2.9e-31 108.8 19.2 3.5e-31 108.5 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD37982.1 - 4.3e-10 39.7 20.6 7e-10 39.0 20.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD37982.1 - 2e-08 34.0 17.6 2.5e-08 33.6 17.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD37982.1 - 0.00019 21.3 17.2 0.00048 19.9 17.2 1.6 1 1 0 1 1 1 1 Olfactory receptor RRM_1 PF00076.22 PVD37984.1 - 8.8e-19 67.1 0.1 1.5e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PVD37984.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_LBD PF02931.23 PVD37987.1 - 1.3e-34 119.5 0.1 1.7e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD37987.1 - 7.5e-17 62.2 4.2 7.5e-17 62.2 4.2 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2583 PF10762.9 PVD37987.1 - 0.13 12.7 0.6 0.36 11.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) PgaD PF13994.6 PVD37987.1 - 0.38 10.8 3.8 0.42 10.7 0.2 2.3 2 1 0 2 2 2 0 PgaD-like protein ABC2_membrane_5 PF13346.6 PVD37987.1 - 3.4 7.2 14.2 0.03 13.9 4.9 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Arm PF00514.23 PVD37988.1 - 1.7e-26 91.4 18.7 0.00065 19.7 0.0 11.9 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD37988.1 - 2.1e-10 40.9 2.8 0.047 14.1 0.1 6.6 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 PVD37988.1 - 5.3e-07 29.3 10.3 0.079 13.3 0.0 8.5 10 1 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.6 PVD37988.1 - 3.2e-06 27.5 8.8 2.8 8.5 0.0 6.9 6 1 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 PVD37988.1 - 0.0005 20.1 8.2 0.17 11.9 0.8 3.6 3 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 PVD37988.1 - 0.00067 18.3 1.3 0.00067 18.3 1.3 3.0 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit Ecm29 PF13001.7 PVD37988.1 - 0.0015 17.3 1.8 0.0055 15.4 1.4 2.1 2 0 0 2 2 2 1 Proteasome stabiliser V-ATPase_H_C PF11698.8 PVD37988.1 - 0.0035 17.4 7.8 2.9 8.0 0.0 4.7 2 1 3 5 5 5 1 V-ATPase subunit H DUF383 PF04063.14 PVD37988.1 - 0.0062 16.2 5.0 1 9.0 0.1 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF383) UNC45-central PF11701.8 PVD37988.1 - 0.015 15.2 9.4 0.15 12.0 1.1 4.6 2 2 1 4 4 4 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 PVD37988.1 - 0.11 12.4 17.9 1.4 8.9 2.2 5.4 2 2 4 6 6 6 0 Domain of unknown function (DUF3361) DinB PF05163.12 PVD37988.1 - 0.11 12.4 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 DinB family IBB PF01749.20 PVD37988.1 - 0.16 12.4 0.4 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Importin beta binding domain Uso1_p115_head PF04869.14 PVD37988.1 - 0.52 9.4 5.9 0.61 9.2 0.2 3.4 3 1 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, head region RasGEF_N_2 PF14663.6 PVD37988.1 - 3.3 8.1 8.9 19 5.7 0.1 4.5 5 1 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DegT_DnrJ_EryC1 PF01041.17 PVD37989.1 - 4.6e-23 82.1 0.0 6.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ldl_recept_b PF00058.17 PVD37990.1 - 1.1e-129 422.6 60.1 5.4e-11 42.8 0.3 28.3 28 1 0 28 28 28 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 PVD37990.1 - 3.3e-100 328.0 244.6 2.9e-11 43.4 9.4 15.2 15 1 0 15 15 14 12 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 PVD37990.1 - 1.7e-49 165.8 205.8 3.3e-10 40.1 8.4 14.4 14 1 1 15 15 11 11 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 PVD37990.1 - 4e-25 88.6 0.0 0.00059 19.2 0.0 8.5 8 2 0 8 8 8 6 Domain of unknown function (DUF5050) cEGF PF12662.7 PVD37990.1 - 6e-16 58.0 70.7 3.2e-08 33.3 0.8 12.6 11 0 0 11 11 11 6 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD37990.1 - 1.2e-12 47.8 37.3 4.2e-08 33.3 9.4 19.2 17 5 4 21 21 10 3 Calcium-binding EGF domain SGL PF08450.12 PVD37990.1 - 4.2e-11 42.9 15.5 0.14 11.8 0.0 11.8 10 5 5 15 15 15 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PVD37990.1 - 1.4e-05 25.2 7.4 36 4.6 0.0 10.2 12 2 2 14 14 13 0 Arylesterase EGF PF00008.27 PVD37990.1 - 0.00048 20.4 4.2 0.00048 20.4 4.2 18.1 21 0 0 21 21 14 8 EGF-like domain DUF3377 PF11857.8 PVD37990.1 - 0.13 12.2 0.3 0.25 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 PVD37990.1 - 0.45 10.6 1.7 1.1 9.4 1.7 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ldl_recept_a PF00057.18 PVD37991.1 - 4.2e-22 78.1 38.8 1.2e-11 44.6 10.5 3.9 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 PVD37991.1 - 4e-08 33.6 0.1 0.0042 17.5 0.1 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 PVD37991.1 - 1.8e-05 24.5 11.0 5.3e-05 23.1 1.0 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD37991.1 - 3.5e-05 23.9 10.3 3.5e-05 23.9 10.3 4.8 2 1 1 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 PVD37991.1 - 0.00027 21.2 9.5 0.00027 21.2 9.5 3.8 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 PVD37991.1 - 0.051 13.1 0.5 3.9 7.0 0.0 2.9 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Tme5_EGF_like PF09064.10 PVD37991.1 - 0.77 9.7 20.9 0.035 14.0 3.9 3.2 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like Dynein_attach_N PF15867.5 PVD37992.1 - 1.1e-26 92.6 1.1 1.9e-26 91.8 1.1 1.4 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 PVD37992.1 - 3.6e-14 53.1 0.0 1.1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 DNA_topoisoIV PF00521.20 PVD37993.1 - 2.8e-100 336.2 0.0 1.2e-99 334.1 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PVD37993.1 - 1.1e-39 135.6 1.4 2.9e-39 134.3 1.4 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PVD37993.1 - 1.1e-28 99.8 0.2 2.1e-28 99.0 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 PVD37993.1 - 1e-15 58.2 0.0 3e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PVD37993.1 - 1.3e-08 35.0 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DTHCT PF08070.11 PVD37993.1 - 0.00031 21.4 20.4 0.00031 21.4 20.4 6.4 4 2 0 5 5 5 1 DTHCT (NUC029) region UQ_con PF00179.26 PVD37994.1 - 7.8e-50 168.2 0.0 8.8e-50 168.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PVD37994.1 - 0.023 14.4 0.1 0.04 13.6 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Pkinase_Tyr PF07714.17 PVD37995.1 - 5.8e-66 222.4 0.1 1.2e-65 221.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD37995.1 - 4.8e-60 203.2 0.0 1.1e-59 202.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Cor1 PF04803.12 PVD37995.1 - 1.9 8.7 8.8 0.36 11.1 4.4 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Adeno_PV PF03910.13 PVD37996.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Sulfotransfer_2 PF03567.14 PVD37997.1 - 4.6e-34 118.5 5.6 1.2e-28 100.8 2.9 2.2 2 0 0 2 2 2 2 Sulfotransferase family Innexin PF00876.18 PVD37998.1 - 7.2e-24 84.7 0.2 1.1e-23 84.2 0.2 1.2 1 0 0 1 1 1 1 Innexin Cupin_8 PF13621.6 PVD37998.1 - 1.8e-06 27.9 0.0 6.6e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 PVD37998.1 - 0.00026 21.4 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 PVD37998.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Cupin domain p450 PF00067.22 PVD37999.1 - 3.9e-44 151.2 0.1 1.7e-40 139.2 0.0 2.3 1 1 1 2 2 2 2 Cytochrome P450 SR-25 PF10500.9 PVD38000.1 - 0.022 14.4 11.7 0.026 14.1 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Amelin PF05111.12 PVD38000.1 - 0.27 10.4 1.8 0.34 10.0 1.8 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Innexin PF00876.18 PVD38002.1 - 1.4e-93 314.0 11.9 1.7e-93 313.7 11.9 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 PVD38003.1 - 0.0045 16.3 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 PVD38004.1 - 7.6e-116 387.2 18.6 9.5e-116 386.9 18.6 1.0 1 0 0 1 1 1 1 Innexin Mito_carr PF00153.27 PVD38005.1 - 1.8e-58 194.5 4.2 2.8e-20 72.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 PVD38005.1 - 0.015 15.5 0.2 1.4 9.2 0.1 3.4 3 1 1 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DTW PF03942.15 PVD38006.1 - 5.4e-25 88.3 0.0 2.4e-24 86.1 0.0 2.0 1 1 0 1 1 1 1 DTW domain FYVE PF01363.21 PVD38006.1 - 0.0037 17.4 1.2 0.0077 16.4 1.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger HTH_31 PF13560.6 PVD38006.1 - 0.011 16.0 0.4 0.022 15.1 0.4 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain G-patch PF01585.23 PVD38007.1 - 5.6e-13 48.6 0.7 1.6e-12 47.1 0.7 1.8 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.7 PVD38007.1 - 1.3e-08 35.2 0.0 3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38007.1 - 2.8e-08 34.1 0.1 0.00035 21.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD38007.1 - 0.0002 21.6 0.0 0.0043 17.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 PVD38007.1 - 0.00039 20.7 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38007.1 - 0.00066 19.9 0.0 0.039 14.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat BLUF PF04940.12 PVD38008.1 - 0.057 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Sensors of blue-light using FAD HGD-D PF06050.13 PVD38008.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component UbiA PF01040.18 PVD38009.1 - 5.7e-56 189.6 14.6 8.2e-56 189.1 14.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HTH_Tnp_Tc5 PF03221.16 PVD38009.1 - 0.034 14.2 0.2 0.096 12.7 0.2 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain FWWh PF14922.6 PVD38010.1 - 5.5e-51 172.4 3.1 9.8e-51 171.6 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function dNK PF01712.19 PVD38011.1 - 4.3e-53 180.2 0.2 5.3e-53 179.9 0.2 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 PVD38011.1 - 2.4e-06 27.8 0.1 8e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD38011.1 - 2.8e-06 27.9 0.3 2.8e-05 24.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PVD38011.1 - 0.00046 19.9 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.6 PVD38011.1 - 0.0016 18.8 0.0 0.03 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain CoaE PF01121.20 PVD38011.1 - 0.032 13.9 0.0 0.086 12.5 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_29 PF13555.6 PVD38011.1 - 0.035 13.9 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 PVD38011.1 - 0.046 12.9 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 PVD38011.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PVD38011.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PVD38011.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 PVD38011.1 - 0.13 12.0 0.1 1.3 8.7 0.1 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 PVD38011.1 - 0.14 12.7 1.0 0.38 11.2 1.0 1.8 1 1 0 1 1 1 0 AAA domain Reprolysin_5 PF13688.6 PVD38012.1 - 2.5e-07 31.1 0.4 6.3e-05 23.2 0.4 2.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD38012.1 - 3.9e-07 30.2 0.0 7.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD38013.1 - 2.9e-08 34.4 25.1 2.9e-08 34.4 25.1 3.6 2 1 2 4 4 4 1 Disintegrin ADAM17_MPD PF16698.5 PVD38013.1 - 3e-06 27.5 15.9 3e-06 27.5 15.9 4.8 2 1 2 4 4 4 2 Membrane-proximal domain, switch, for ADAM17 Reprolysin_5 PF13688.6 PVD38014.1 - 9e-10 39.0 0.0 9e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 PVD38014.1 - 3.7e-06 27.6 33.2 0.0023 18.7 17.1 2.9 2 1 0 2 2 2 2 Disintegrin Reprolysin_2 PF13574.6 PVD38014.1 - 7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PVD38014.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD38015.1 - 2.1e-07 31.7 34.7 0.0007 20.3 20.2 2.7 2 0 0 2 2 2 2 Disintegrin Reprolysin_5 PF13688.6 PVD38015.1 - 2.1e-07 31.3 1.0 1.5e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 PVD38015.1 - 0.0025 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD38016.1 - 0.0015 19.3 19.9 0.0034 18.2 19.9 1.6 1 0 0 1 1 1 1 Disintegrin UPF0121 PF03661.13 PVD38016.1 - 0.1 11.9 0.1 0.89 8.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) p450 PF00067.22 PVD38017.1 - 0.0027 16.5 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4215 PF13948.6 PVD38017.1 - 0.0051 17.2 9.8 0.053 14.0 0.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4215) Disintegrin PF00200.23 PVD38017.1 - 0.055 14.3 11.0 0.18 12.6 7.0 2.8 2 1 0 2 2 2 0 Disintegrin RVT_1 PF00078.27 PVD38018.1 - 9.8e-20 71.0 0.0 1.2e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADAM17_MPD PF16698.5 PVD38020.1 - 6.7e-08 32.8 46.1 2.2e-05 24.7 8.0 8.3 5 2 3 8 8 8 3 Membrane-proximal domain, switch, for ADAM17 Disintegrin PF00200.23 PVD38020.1 - 0.0018 19.0 19.4 0.0018 19.0 19.4 5.8 3 2 1 4 4 4 2 Disintegrin UDPG_MGDP_dh PF00984.19 PVD38020.1 - 0.09 13.0 0.6 11 6.3 0.0 2.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Reprolysin_5 PF13688.6 PVD38021.1 - 4.8e-10 39.9 0.1 2.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM17_MPD PF16698.5 PVD38021.1 - 5.1e-05 23.6 6.1 5.1e-05 23.6 6.1 4.6 5 0 0 5 5 5 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_2 PF13574.6 PVD38021.1 - 6.8e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 PVD38021.1 - 0.0081 16.9 1.5 0.0081 16.9 1.5 3.8 2 1 1 3 3 3 1 Disintegrin Disintegrin PF00200.23 PVD38022.1 - 1.2e-12 48.4 61.7 9.4e-08 32.7 27.7 5.3 3 2 4 7 7 7 2 Disintegrin Reprolysin_2 PF13574.6 PVD38022.1 - 4.7e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 PVD38022.1 - 3e-05 24.3 12.5 3e-05 24.3 12.5 7.5 5 2 2 7 7 7 2 Membrane-proximal domain, switch, for ADAM17 Reprolysin_5 PF13688.6 PVD38022.1 - 4.4e-05 23.7 0.2 0.00035 20.8 0.0 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 Glycophorin_A PF01102.18 PVD38022.1 - 0.17 12.2 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Reprolysin_2 PF13574.6 PVD38023.1 - 1.6e-10 41.2 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 PVD38023.1 - 1.2e-08 35.4 0.2 2.4e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 PVD38023.1 - 0.0047 17.7 3.5 0.0047 17.7 3.5 1.7 2 0 0 2 2 2 1 Disintegrin Reprolysin PF01421.19 PVD38023.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 PVD38023.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Cwf_Cwc_15 PF04889.12 PVD38023.1 - 0.082 12.6 8.6 0.084 12.6 8.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.28 PVD38024.1 - 1.9e-78 264.0 0.1 2.2e-52 178.1 0.1 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Guanylate_kin PF00625.21 PVD38024.1 - 1.4e-48 165.0 0.0 2.5e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase DMAP_binding PF06464.11 PVD38024.1 - 1.3e-24 87.1 2.0 3.1e-24 85.9 2.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain L27 PF02828.16 PVD38024.1 - 7.5e-11 41.6 1.9 8.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 PVD38024.1 - 1.4e-07 31.7 0.2 3.9e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 PVD38024.1 - 2e-06 27.3 0.1 5.6e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD38024.1 - 2.2e-06 27.3 0.0 6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GvpG PF05120.12 PVD38024.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Gas vesicle protein G SH3_9 PF14604.6 PVD38024.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 PVD38024.1 - 0.0086 16.4 0.1 0.031 14.6 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD38024.1 - 0.016 15.1 0.1 0.048 13.5 0.1 1.9 1 0 0 1 1 1 0 PDZ domain MCM2_N PF12619.8 PVD38024.1 - 1.6 9.0 6.2 4.6 7.5 6.2 1.7 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Pkinase PF00069.25 PVD38026.1 - 1e-55 188.9 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38026.1 - 1.3e-28 100.0 0.0 1.7e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD38026.1 - 0.00043 19.7 0.0 0.00076 18.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PVD38026.1 - 0.009 16.0 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PVD38026.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 PVD38026.1 - 0.12 12.0 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Vinculin PF01044.19 PVD38027.1 - 5.6e-63 213.6 13.9 8.1e-40 136.9 8.1 3.1 3 0 0 3 3 3 3 Vinculin family DUF4507 PF14964.6 PVD38027.1 - 0.0035 16.3 0.1 0.0077 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) DUF4051 PF13260.6 PVD38027.1 - 0.31 10.8 2.6 0.38 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) PDZ_6 PF17820.1 PVD38028.1 - 4.7e-11 42.4 0.1 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PVD38028.1 - 1.4e-10 41.3 0.2 4.8e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD38028.1 - 0.00043 20.6 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain CNPase PF05881.12 PVD38029.1 - 2e-28 99.6 0.0 3.6e-17 62.7 0.0 2.4 2 1 0 2 2 2 2 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_33 PF13671.6 PVD38029.1 - 2.9e-10 40.5 0.0 6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PVD38029.1 - 0.068 13.6 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1181 PF06680.11 PVD38030.1 - 0.093 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) STELLO PF03385.17 PVD38032.1 - 0.0043 15.9 1.3 0.0066 15.3 1.3 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases HSP70 PF00012.20 PVD38033.1 - 3.4e-240 798.4 6.8 3.9e-240 798.2 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD38033.1 - 1.2e-16 60.4 0.2 3.9e-14 52.2 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 PVD38033.1 - 0.0063 16.9 4.3 1.5 9.3 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 PVD38033.1 - 0.017 14.9 0.0 0.53 10.0 0.0 2.9 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PVD38033.1 - 0.059 12.6 0.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 PVD38033.1 - 0.072 12.3 0.3 1.3 8.2 0.0 2.9 4 0 0 4 4 4 0 StbA protein Yae1_N PF09811.9 PVD38040.1 - 0.056 13.2 0.5 0.12 12.2 0.3 1.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ufd2P_core PF10408.9 PVD38042.1 - 5.3e-92 309.4 0.0 7.8e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core UQ_con PF00179.26 PVD38042.1 - 1.1e-26 93.1 0.0 2.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PVD38042.1 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PVD38042.1 - 0.11 12.7 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 RWD domain CSTF2_hinge PF14327.6 PVD38042.1 - 1.5 9.4 5.4 24 5.5 0.1 3.7 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 7tm_1 PF00001.21 PVD38043.1 - 2.8e-11 43.2 2.8 3.7e-11 42.9 2.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD38043.1 - 2.3e-06 27.1 1.3 3.6e-06 26.5 1.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD38043.1 - 7.4e-05 22.2 4.9 7.4e-05 22.2 4.9 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF639 PF04842.12 PVD38043.1 - 0.052 13.0 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) 7TM_GPCR_Srw PF10324.9 PVD38044.1 - 3.3e-12 46.3 4.4 1.8e-09 37.4 0.9 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 PVD38044.1 - 3.9e-08 32.9 3.7 3.9e-08 32.9 3.7 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 4HB PF17947.1 PVD38044.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Four helical bundle domain COX1 PF00115.20 PVD38044.1 - 6.2 5.5 10.2 2.6 6.8 3.1 2.6 2 1 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I 7tm_1 PF00001.21 PVD38045.1 - 0.0048 16.3 4.0 0.0064 15.8 4.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD38046.1 - 1.2e-16 60.8 17.3 3.5e-15 56.1 14.3 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD38046.1 - 5.8e-10 38.9 10.2 2.2e-06 27.2 8.1 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 PVD38046.1 - 5e-05 23.1 15.5 5e-05 23.1 15.5 1.9 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD38046.1 - 7.8e-05 22.2 9.5 7.8e-05 22.2 9.5 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 PVD38046.1 - 1.2 9.1 12.2 0.15 12.0 7.5 1.9 2 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.21 PVD38047.1 - 1.9e-25 89.7 15.0 2.6e-25 89.3 15.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD38047.1 - 5.8e-11 42.2 18.4 6.9e-10 38.7 18.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD38047.1 - 5.9e-05 22.6 15.9 8.8e-05 22.0 15.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD38047.1 - 0.036 13.7 20.3 0.073 12.7 16.9 2.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 PVD38047.1 - 2.4 8.1 14.5 0.03 14.3 4.8 2.7 2 2 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Pilin_N PF07790.11 PVD38048.1 - 0.23 12.4 2.6 2.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF5383 PF17355.2 PVD38048.1 - 2.6 8.4 4.3 5.4 7.4 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) HOK_GEF PF01848.16 PVD38048.1 - 3.3 7.2 6.2 12 5.4 0.2 2.5 2 0 0 2 2 2 0 Hok/gef family SPW PF03779.14 PVD38048.1 - 6.7 6.4 14.2 7.2 6.3 2.2 2.5 2 0 0 2 2 2 0 SPW repeat C1q PF00386.21 PVD38050.1 - 2e-08 34.5 0.1 3.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 C1q domain Nop10p PF04135.12 PVD38050.1 - 0.035 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family MMTV_SAg PF01054.17 PVD38050.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Prefoldin_2 PF01920.20 PVD38053.1 - 1.2e-20 73.4 12.1 1.4e-20 73.2 12.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Tnp_22_trimer PF17489.2 PVD38053.1 - 0.02 14.9 2.1 0.045 13.7 2.1 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain DUF5320 PF17253.2 PVD38053.1 - 0.022 15.8 3.5 0.023 15.8 0.3 1.9 1 1 0 2 2 2 0 Family of unknown function (DUF5320) SOAR PF16533.5 PVD38053.1 - 0.063 13.3 4.1 1.7 8.7 0.8 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region Phage_GP20 PF06810.11 PVD38053.1 - 0.21 11.4 11.5 1.2 8.9 3.8 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 ApoO PF09769.9 PVD38053.1 - 0.21 11.6 0.9 2.5 8.1 0.2 2.0 1 1 1 2 2 2 0 Apolipoprotein O 60KD_IMP PF02096.20 PVD38053.1 - 1.3 8.9 3.3 0.43 10.5 0.3 1.6 1 1 1 2 2 2 0 60Kd inner membrane protein XhlA PF10779.9 PVD38053.1 - 2.9 8.2 10.7 0.52 10.6 5.4 2.1 2 1 0 2 2 2 0 Haemolysin XhlA DUF724 PF05266.14 PVD38053.1 - 4.1 7.2 10.9 8.7 6.1 10.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SHQ1 PF04925.15 PVD38054.1 - 3.6e-64 215.5 0.3 5.3e-64 215.0 0.3 1.3 1 0 0 1 1 1 1 SHQ1 protein CobT PF06213.12 PVD38054.1 - 0.15 11.4 16.8 0.22 10.9 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 PVD38054.1 - 0.37 10.1 12.7 0.65 9.3 12.7 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 PVD38054.1 - 0.85 7.8 16.6 1.2 7.3 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 PVD38054.1 - 1.4 8.9 15.7 2.6 8.1 15.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 PVD38054.1 - 2 8.3 18.3 10 5.9 17.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Paf1 PF03985.13 PVD38054.1 - 2.3 7.1 13.4 3.3 6.6 13.4 1.2 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.11 PVD38054.1 - 2.8 6.4 13.9 4.4 5.7 13.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SspB PF04386.13 PVD38054.1 - 3 7.7 5.2 5.2 6.9 5.2 1.4 1 0 0 1 1 1 0 Stringent starvation protein B Nop14 PF04147.12 PVD38054.1 - 3.4 5.8 22.0 4.9 5.2 22.0 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 PVD38054.1 - 5 7.6 6.6 8.3 6.8 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 HLH PF00010.26 PVD38055.1 - 1.4e-15 56.9 0.3 2.6e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zip PF02535.22 PVD38055.1 - 0.027 13.7 4.0 0.035 13.3 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Spore_YpjB PF09577.10 PVD38055.1 - 0.039 13.8 0.2 0.062 13.1 0.2 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DNAPolymera_Pol PF11590.8 PVD38055.1 - 0.091 12.7 1.0 0.19 11.6 1.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol IDO PF01231.18 PVD38056.1 - 9e-103 344.4 0.1 4.1e-102 342.2 0.1 1.8 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 PVD38056.1 - 8.4e-05 21.5 0.0 0.0013 17.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Ceramidase_alk PF04734.13 PVD38057.1 - 1.2e-233 776.4 0.0 1.4e-233 776.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 PVD38057.1 - 4.1e-56 189.5 0.0 6.2e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal P4Ha_N PF08336.11 PVD38058.1 - 2.6e-35 121.4 0.1 4.6e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 PVD38058.1 - 8.7e-16 58.6 0.1 1.8e-15 57.6 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 PVD38058.1 - 0.00012 21.9 0.1 0.00082 19.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD38058.1 - 0.031 14.4 0.2 0.094 12.8 0.2 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF1593 PF07632.11 PVD38058.1 - 0.054 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) 7tm_1 PF00001.21 PVD38059.1 - 3.5e-05 23.3 1.8 0.0081 15.5 0.1 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD38059.1 - 0.0001 22.2 0.3 0.0001 22.2 0.3 1.7 2 0 0 2 2 2 1 Olfactory receptor TEX33 PF15400.6 PVD38060.1 - 7.7e-11 42.7 0.0 2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family CBM32 PF18344.1 PVD38062.1 - 0.063 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding module family 32 DUF2623 PF11115.8 PVD38065.1 - 0.087 12.9 0.0 0.093 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Zip PF02535.22 PVD38068.1 - 7.7e-60 202.9 4.8 7.7e-60 202.9 4.8 2.7 3 1 0 3 3 3 1 ZIP Zinc transporter DUF685 PF05085.12 PVD38068.1 - 0.24 10.7 0.0 0.45 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) PPL5 PF18168.1 PVD38068.1 - 5.2 6.3 7.3 11 5.2 7.3 1.5 1 0 0 1 1 1 0 Prim-pol family 5 RAB3GAP2_N PF14655.6 PVD38070.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RA PF00788.23 PVD38070.1 - 0.071 13.8 0.1 0.28 11.8 0.0 1.9 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain PDEase_I PF00233.19 PVD38072.1 - 1.8e-82 276.6 7.0 3.2e-82 275.8 7.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 PVD38072.1 - 2e-31 107.6 0.1 4.6e-31 106.4 0.1 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal INCA1 PF15142.6 PVD38077.1 - 0.016 15.2 0.3 0.021 14.9 0.3 1.2 1 0 0 1 1 1 0 INCA1 WD40 PF00400.32 PVD38079.1 - 3.2e-21 75.3 9.7 5e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38079.1 - 1e-05 25.8 0.0 0.02 15.2 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PVD38079.1 - 3.3e-05 24.2 1.1 3.2 8.3 0.0 4.1 3 1 1 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.11 PVD38079.1 - 0.0058 15.4 0.1 3.4 6.3 0.0 3.0 1 1 1 3 3 3 2 Nup133 N terminal like WD40 PF00400.32 PVD38080.1 - 1.1e-16 60.8 9.9 2e-05 25.2 0.3 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 PVD38080.1 - 1.7e-06 27.0 0.3 0.055 12.1 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 YchF-GTPase_C PF06071.13 PVD38082.1 - 1.2e-38 131.2 0.5 2.8e-38 130.0 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PVD38082.1 - 5.9e-23 81.1 0.0 2.1e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD38082.1 - 4.3e-07 29.6 0.0 9.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 PVD38082.1 - 0.0014 18.8 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TGS PF02824.21 PVD38082.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 PVD38082.1 - 0.0087 15.1 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 PVD38082.1 - 0.051 13.6 0.0 12 5.9 0.0 2.4 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 PVD38082.1 - 0.077 13.5 0.0 0.89 10.1 0.0 2.5 1 1 0 1 1 1 0 ABC transporter zf-H2C2_2 PF13465.6 PVD38084.1 - 5e-13 48.8 9.2 1e-07 32.0 2.9 4.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD38084.1 - 4.1e-12 45.8 30.5 3.3e-05 24.1 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD38084.1 - 1e-05 25.9 29.5 0.0009 19.9 2.6 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger YjbF PF11102.8 PVD38084.1 - 0.0017 18.2 0.1 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF zf-C2H2_8 PF15909.5 PVD38084.1 - 0.0037 17.5 5.3 0.0073 16.6 4.5 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon Keratin PF02422.16 PVD38084.1 - 0.013 15.1 2.4 0.013 15.1 2.4 3.0 2 0 0 2 2 2 0 Keratin Pox_Ag35 PF03286.14 PVD38084.1 - 0.14 12.0 4.4 0.081 12.7 1.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-C2H2_jaz PF12171.8 PVD38084.1 - 0.21 11.9 7.0 5.1 7.5 3.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PVD38084.1 - 0.22 11.6 16.9 0.66 10.1 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 PVD38084.1 - 1.2 9.6 7.8 0.48 10.9 1.7 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CENP-B_dimeris PF09026.10 PVD38084.1 - 2.2 8.7 8.8 4.3 7.8 8.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zinc_ribbon_15 PF17032.5 PVD38084.1 - 3.6 8.4 7.0 1.6e+02 3.1 6.9 2.6 1 1 0 1 1 1 0 zinc-ribbon family Zn_Tnp_IS1 PF03811.13 PVD38084.1 - 6.4 6.6 6.7 17 5.2 1.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain NAD-GH PF10712.9 PVD38087.1 - 1.5e-129 433.1 40.0 1.9e-129 432.8 40.0 1.0 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase HSP70 PF00012.20 PVD38088.1 - 5.1e-207 688.8 4.6 5.9e-207 688.6 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PVD38088.1 - 8.7e-14 51.1 0.1 1.4e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 PVD38088.1 - 0.00036 20.3 0.0 0.0014 18.4 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PVD38088.1 - 0.011 15.0 0.1 0.048 12.9 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 PVD38088.1 - 0.087 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 StbA protein Cnd1_N PF12922.7 PVD38088.1 - 0.21 11.4 0.8 0.4 10.5 0.8 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF883 PF05957.13 PVD38088.1 - 1.9 9.1 7.1 1.4 9.6 2.8 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Nuf2 PF03800.14 PVD38091.1 - 2.8e-22 79.3 0.6 1.2e-21 77.3 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family Prefoldin_2 PF01920.20 PVD38092.1 - 0.0014 18.6 6.4 0.002 18.1 6.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF3618 PF12277.8 PVD38092.1 - 0.05 13.9 0.6 0.092 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF4376 PF14301.6 PVD38092.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) APG6_N PF17675.1 PVD38092.1 - 0.096 13.2 7.8 0.63 10.6 7.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region BCL_N PF04714.13 PVD38092.1 - 0.69 10.0 3.2 0.84 9.8 1.0 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Ank_2 PF12796.7 PVD38093.1 - 4.2e-22 78.5 5.3 4.3e-07 30.4 0.4 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD38093.1 - 1.1e-21 76.6 5.8 4.3e-10 39.6 0.2 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Patatin PF01734.22 PVD38093.1 - 9.5e-18 65.1 1.0 3.6e-17 63.2 1.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.6 PVD38093.1 - 3.2e-15 56.3 1.2 7.7e-05 23.2 0.0 5.0 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38093.1 - 4.2e-15 54.4 3.9 0.079 13.6 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PVD38093.1 - 5.2e-15 55.1 8.3 0.12 12.8 0.0 7.6 8 0 0 8 8 8 6 Ankyrin repeat Acyl-CoA_dh_1 PF00441.24 PVD38094.1 - 4.2e-38 130.9 0.1 6.5e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PVD38094.1 - 1.9e-30 105.8 0.1 4.7e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PVD38094.1 - 1.2e-17 63.9 0.0 2.7e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PVD38094.1 - 4.5e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Y_phosphatase PF00102.27 PVD38095.1 - 4.9e-72 242.3 0.1 8.3e-72 241.5 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 PVD38095.1 - 3.6e-65 216.3 3.1 2e-19 69.7 0.5 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 PVD38095.1 - 2.2e-42 142.7 7.1 1.7e-14 53.4 0.5 4.6 4 0 0 4 4 4 4 PDZ domain FERM_M PF00373.18 PVD38095.1 - 6.3e-21 75.0 0.2 6.3e-21 75.0 0.2 2.2 2 0 0 2 2 2 1 FERM central domain PDZ_2 PF13180.6 PVD38095.1 - 1.6e-17 63.6 0.4 0.0016 18.7 0.0 5.0 4 0 0 4 4 4 3 PDZ domain FERM_C PF09380.10 PVD38095.1 - 4.1e-10 39.9 0.0 8.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain KIND PF16474.5 PVD38095.1 - 3.9e-07 30.2 1.4 2e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain FERM_N PF09379.10 PVD38095.1 - 9.8e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Y_phosphatase3 PF13350.6 PVD38095.1 - 0.0072 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PVD38095.1 - 0.015 15.1 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain FYRC PF05965.14 PVD38095.1 - 0.14 12.3 0.0 49 4.2 0.0 3.6 4 0 0 4 4 3 0 F/Y rich C-terminus DUF5528 PF17666.1 PVD38096.1 - 0.00037 20.5 1.9 0.00075 19.5 1.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5528) MFS_1 PF07690.16 PVD38098.1 - 0.009 15.0 20.3 0.024 13.6 19.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily SUR7 PF06687.12 PVD38098.1 - 0.011 15.3 0.2 0.011 15.3 0.2 1.7 2 0 0 2 2 2 0 SUR7/PalI family Zip PF02535.22 PVD38098.1 - 0.028 13.6 8.6 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 PVD38098.1 - 0.64 9.4 24.3 5 6.5 20.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 PVD38099.1 - 2.3e-13 49.8 34.0 0.0014 17.6 6.3 4.4 4 0 0 4 4 4 4 Major Facilitator Superfamily DUF2534 PF10749.9 PVD38099.1 - 0.018 15.2 0.3 2.9 8.1 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) SmAKAP PF15127.6 PVD38099.1 - 0.22 12.7 0.7 1 10.6 0.1 2.2 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein GRP PF07172.11 PVD38099.1 - 2 9.2 4.5 85 3.9 0.1 4.2 4 0 0 4 4 4 0 Glycine rich protein family P53_tetramer PF07710.11 PVD38101.1 - 0.025 13.9 0.0 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 P53 tetramerisation motif TraP PF07296.11 PVD38101.1 - 0.11 11.7 0.1 0.3 10.2 0.1 1.7 1 0 0 1 1 1 0 TraP protein zf-C2H2_4 PF13894.6 PVD38102.1 - 0.041 14.7 1.8 0.13 13.2 1.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger 7tm_1 PF00001.21 PVD38103.1 - 2.5e-38 131.9 8.6 4e-38 131.2 8.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_UL49_5 PF05702.11 PVD38103.1 - 0.17 12.0 2.3 0.47 10.6 0.1 2.9 3 1 1 4 4 4 0 Herpesvirus UL49.5 envelope/tegument protein Ras PF00071.22 PVD38104.1 - 1.3e-26 93.1 0.0 1.9e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD38104.1 - 1.3e-14 54.4 0.0 2.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD38104.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family DnaJ PF00226.31 PVD38105.1 - 1.1e-05 25.4 0.1 1.8e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain USP8_interact PF08941.10 PVD38106.1 - 2.7e-84 281.4 4.4 2.7e-84 281.4 4.4 4.0 4 1 1 5 5 5 1 USP8 interacting zf-C3HC4_2 PF13923.6 PVD38106.1 - 2.6e-09 36.8 7.0 2.6e-09 36.8 7.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD38106.1 - 3.8e-08 33.5 6.3 1e-07 32.2 6.3 1.8 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 PVD38106.1 - 9.4e-08 32.1 0.2 2.4e-06 27.6 0.1 3.0 2 0 0 2 2 2 1 U-box domain zf-C3HC4 PF00097.25 PVD38106.1 - 9.5e-08 31.8 6.2 9.5e-08 31.8 6.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD38106.1 - 1.5e-07 31.6 3.5 5.7e-07 29.7 3.5 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD38106.1 - 2.4e-06 27.5 7.5 6.1e-06 26.2 7.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PVD38106.1 - 6.3e-06 25.9 3.1 1.6e-05 24.6 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD38106.1 - 5.6e-05 23.2 6.8 0.00015 21.9 6.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PVD38106.1 - 8.1e-05 22.4 0.6 0.00024 20.9 0.6 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 PVD38106.1 - 0.00018 21.3 2.2 0.00018 21.3 2.2 2.1 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 PVD38106.1 - 0.0002 21.3 3.6 0.00062 19.7 3.6 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 PVD38106.1 - 0.0016 18.6 1.7 0.0089 16.1 1.7 2.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PVD38106.1 - 0.002 18.1 0.7 0.0051 16.8 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.16 PVD38106.1 - 0.0052 16.8 1.3 0.016 15.1 1.3 1.9 1 0 0 1 1 1 1 Seven in absentia protein family zf-TRAF PF02176.18 PVD38106.1 - 0.25 12.1 3.7 3.1 8.6 2.8 2.7 1 1 1 2 2 2 0 TRAF-type zinc finger Prok-RING_4 PF14447.6 PVD38106.1 - 0.52 10.2 6.5 2.2 8.2 6.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 PVD38106.1 - 1.7 9.2 7.5 4.2 7.9 5.3 2.7 2 1 1 3 3 2 0 TRAF-like zinc-finger Zn_ribbon_17 PF17120.5 PVD38106.1 - 2.3 7.9 8.6 0.42 10.3 3.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_5 PF17121.5 PVD38106.1 - 3.3 7.7 4.8 11 6.0 4.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_18 PF15024.6 PVD38108.1 - 3.5e-231 768.7 0.4 4.2e-231 768.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.6 PVD38108.1 - 3e-18 65.9 0.0 6.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) CEP63 PF17045.5 PVD38111.1 - 0.0023 17.9 28.0 0.0023 17.9 28.0 2.3 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa TPR_MLP1_2 PF07926.12 PVD38111.1 - 3.4 7.7 29.6 4.9 7.2 9.1 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPAR_LY6_2 PF16975.5 PVD38112.1 - 1.6e-21 76.5 13.7 2.3e-21 76.0 13.7 1.2 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 I-set PF07679.16 PVD38115.1 - 6.9e-106 346.6 0.4 1.4e-21 76.3 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin I-set domain Pkinase PF00069.25 PVD38115.1 - 5.2e-72 242.4 0.0 7.6e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 PVD38115.1 - 1.4e-68 227.4 8.2 9.4e-16 58.2 0.1 7.3 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 PVD38115.1 - 5.6e-39 132.2 7.0 4.7e-08 33.1 0.3 6.2 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 PVD38115.1 - 9.8e-38 128.4 5.5 3.8e-07 30.4 0.0 6.0 6 0 0 6 6 5 5 Immunoglobulin domain Pkinase_Tyr PF07714.17 PVD38115.1 - 2.7e-36 125.2 0.0 4.7e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 PVD38115.1 - 2.6e-14 53.3 0.3 1.8e-13 50.6 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain V-set PF07686.17 PVD38115.1 - 3.1e-14 53.1 19.2 0.097 12.9 0.5 9.4 5 5 1 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD38115.1 - 6.3e-10 39.0 0.3 0.66 10.1 0.1 6.0 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD38115.1 - 9.7e-09 35.5 5.7 0.75 10.2 0.0 5.6 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD38115.1 - 1.6e-08 34.6 1.9 0.17 12.1 0.0 5.3 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 PVD38115.1 - 1.3e-06 27.8 0.1 1.4 8.5 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin domain C1-set PF07654.15 PVD38115.1 - 2.6e-06 27.7 3.5 0.86 10.0 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 PVD38115.1 - 4.8e-06 26.7 2.2 4.2 7.6 0.1 5.5 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 PVD38115.1 - 0.00045 20.2 0.5 12 6.0 0.0 4.7 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 PVD38115.1 - 0.00072 18.4 0.0 1.2 7.8 0.0 4.1 4 1 1 5 5 5 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.11 PVD38115.1 - 0.003 17.5 0.1 18 5.3 0.0 3.7 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 PVD38115.1 - 0.005 16.8 1.3 40 4.3 0.0 4.3 5 0 0 5 5 4 0 C17orf99 Ig domain DUF11 PF01345.18 PVD38115.1 - 0.011 16.1 0.3 0.47 10.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF11 PKD_3 PF16820.5 PVD38115.1 - 0.012 15.3 0.2 1.1 9.0 0.0 3.5 3 0 0 3 3 3 0 PKD-like domain Kdo PF06293.14 PVD38115.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD38115.1 - 0.019 14.9 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family fn3 PF00041.21 PVD38116.1 - 4e-16 59.1 2.7 9.1e-16 58.0 2.7 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD38116.1 - 0.00025 21.5 0.6 0.0009 19.8 0.6 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 PVD38116.1 - 0.00071 19.4 1.3 0.0017 18.2 1.3 1.6 1 0 0 1 1 1 1 Tissue factor fn3_4 PF16794.5 PVD38116.1 - 0.031 14.2 0.1 0.12 12.3 0.1 1.9 1 1 0 1 1 1 0 Fibronectin-III type domain I-set PF07679.16 PVD38117.1 - 7.4e-186 602.9 0.1 1.7e-23 82.5 0.0 10.3 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD38117.1 - 1.6e-124 406.7 2.5 2.2e-15 57.0 0.0 10.5 10 0 0 10 10 10 9 Immunoglobulin domain Ig_2 PF13895.6 PVD38117.1 - 1.7e-78 259.0 7.1 2.7e-12 46.8 0.0 9.6 10 0 0 10 10 9 8 Immunoglobulin domain ig PF00047.25 PVD38117.1 - 1.1e-77 256.2 10.8 4.7e-13 49.1 0.0 10.6 10 1 0 10 10 10 8 Immunoglobulin domain Pkinase PF00069.25 PVD38117.1 - 2.4e-68 230.4 0.0 3.9e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 PVD38117.1 - 5.2e-47 158.5 20.1 3.7e-06 27.1 0.4 15.6 8 7 1 9 9 9 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 PVD38117.1 - 2.1e-35 122.3 0.0 3.4e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 PVD38117.1 - 1.7e-24 85.7 0.7 0.0045 17.0 0.0 8.8 9 0 0 9 9 9 6 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 PVD38117.1 - 2.4e-13 50.1 8.3 0.043 14.1 0.0 7.9 7 1 0 7 7 7 4 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 PVD38117.1 - 2e-12 47.0 4.3 0.88 9.7 0.0 9.5 10 0 0 10 10 10 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 PVD38117.1 - 2.1e-12 47.3 11.7 0.091 13.2 0.0 8.4 7 2 0 7 7 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 PVD38117.1 - 2.9e-10 40.4 1.0 0.049 14.0 0.0 6.2 6 0 0 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 PVD38117.1 - 9.5e-10 37.9 0.0 0.51 9.9 0.0 6.1 6 0 0 6 6 6 2 Immunoglobulin domain Receptor_2B4 PF11465.8 PVD38117.1 - 7e-08 32.6 0.1 22 5.3 0.0 7.5 8 0 0 8 8 8 0 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 PVD38117.1 - 1.4e-07 31.4 0.6 1.6 8.8 0.0 6.7 7 0 0 7 7 6 1 C17orf99 Ig domain V-set_CD47 PF08204.11 PVD38117.1 - 5.1e-06 26.5 5.3 0.82 9.7 0.0 5.6 6 1 0 6 6 6 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 PVD38117.1 - 8.3e-06 25.5 4.0 1 9.2 0.1 5.7 6 0 0 6 6 5 2 Adenovirus E3 region protein CR1 Kdo PF06293.14 PVD38117.1 - 0.0015 17.9 0.3 0.003 17.0 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD38117.1 - 0.0097 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2-set PF05790.15 PVD38117.1 - 0.0099 16.0 3.4 36 4.6 0.0 6.3 6 1 0 6 6 6 0 Immunoglobulin C2-set domain Dis3l2_C_term PF17877.1 PVD38117.1 - 0.044 14.1 0.5 8.3 6.8 0.0 2.9 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal zf-RRN7 PF11781.8 PVD38117.1 - 0.36 10.6 7.0 21 4.9 0.1 4.4 3 1 1 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF2218 PF09981.9 PVD38118.1 - 0.0054 17.1 0.2 3.1 8.2 0.0 3.3 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2218) Stork_head PF10264.9 PVD38118.1 - 3.3 7.9 9.2 23 5.2 0.3 3.6 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain DUF2218 PF09981.9 PVD38119.1 - 0.0029 18.0 0.0 0.48 10.8 0.0 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2218) I-set PF07679.16 PVD38120.1 - 0 1350.4 0.0 7.4e-23 80.4 0.0 23.3 21 2 0 21 21 21 21 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD38120.1 - 7.1e-267 862.9 4.5 2.3e-15 56.9 0.0 21.8 21 0 0 21 21 21 21 Immunoglobulin domain Ig_2 PF13895.6 PVD38120.1 - 1.4e-148 483.5 12.6 1.1e-10 41.7 0.0 21.3 21 0 0 21 21 21 19 Immunoglobulin domain ig PF00047.25 PVD38120.1 - 1.5e-132 432.1 16.2 2.7e-11 43.5 0.0 22.6 22 2 0 22 22 22 18 Immunoglobulin domain V-set PF07686.17 PVD38120.1 - 1.3e-59 199.1 33.3 0.00023 21.3 0.0 29.7 21 15 1 22 22 22 13 Immunoglobulin V-set domain C2-set_2 PF08205.12 PVD38120.1 - 2.2e-38 130.2 13.4 0.0023 18.0 0.0 19.4 20 0 0 20 20 20 7 CD80-like C2-set immunoglobulin domain Spectrin PF00435.21 PVD38120.1 - 5.1e-32 110.5 129.4 3.7e-09 37.0 1.0 16.1 16 1 1 17 17 14 10 Spectrin repeat Ig_5 PF16681.5 PVD38120.1 - 1.1e-17 64.1 1.9 0.23 11.9 0.0 12.2 12 0 0 12 12 12 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 PVD38120.1 - 2.3e-11 43.6 1.6 0.97 9.5 0.0 10.7 14 0 0 14 14 11 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD38120.1 - 1.5e-10 40.5 0.1 0.08 12.5 0.0 8.0 10 0 0 10 10 10 2 Immunoglobulin domain BiPBP_C PF06832.12 PVD38120.1 - 1.6e-10 40.9 0.0 15 5.7 0.0 11.2 14 0 0 14 14 13 0 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 PVD38120.1 - 1.8e-09 37.8 8.7 4.5 7.7 0.1 11.2 12 0 0 12 12 12 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 PVD38120.1 - 1.9e-09 37.7 0.0 5.2 7.3 0.0 9.6 11 0 0 11 11 10 1 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 PVD38120.1 - 1.1e-07 31.8 8.9 0.41 10.7 0.0 11.2 13 2 1 14 14 14 1 C17orf99 Ig domain Herpes_gE PF02480.16 PVD38120.1 - 0.0002 20.2 0.3 0.61 8.8 0.0 4.5 4 1 1 5 5 5 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.15 PVD38120.1 - 0.00035 20.3 1.6 61 3.5 0.0 8.1 10 0 0 10 10 10 0 Adenovirus E3 region protein CR1 C2-set PF05790.15 PVD38120.1 - 0.0011 19.2 4.4 56 4.0 0.0 7.5 8 0 0 8 8 8 0 Immunoglobulin C2-set domain Antimicrobial11 PF08106.11 PVD38121.1 - 2 8.6 14.7 11 6.3 0.3 4.5 4 0 0 4 4 4 0 Formaecin family PSI PF01437.25 PVD38121.1 - 2.2 8.9 5.8 80 3.9 5.8 2.4 1 1 0 1 1 1 0 Plexin repeat WD40 PF00400.32 PVD38122.1 - 1.8e-05 25.4 2.2 0.43 11.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38122.1 - 0.084 13.2 0.0 9.6 6.6 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SPG48 PF14764.6 PVD38123.1 - 1.5e-34 119.0 1.6 1.5e-34 119.0 1.6 3.2 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking EF-hand_7 PF13499.6 PVD38124.1 - 1.3e-30 105.6 11.5 1.2e-11 44.9 0.3 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PVD38124.1 - 1e-26 90.5 8.8 2.6e-05 23.8 0.0 6.3 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 PVD38124.1 - 2.2e-26 89.4 12.3 6.1e-06 25.4 0.3 6.5 6 1 0 6 6 6 5 EF hand EF-hand_5 PF13202.6 PVD38124.1 - 8.9e-15 53.4 8.0 0.00011 21.6 0.1 5.7 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 PVD38124.1 - 3.3e-13 49.3 9.2 0.00026 20.8 0.1 5.6 4 2 1 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PVD38124.1 - 3.2e-05 24.2 2.4 0.23 11.8 0.1 3.3 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 PVD38124.1 - 0.00031 20.5 1.2 2.4 8.1 0.0 3.9 3 1 1 4 4 4 2 EF hand DUF5580 PF17743.1 PVD38124.1 - 0.00041 19.0 0.0 0.0038 15.9 0.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5580) RST PF12174.8 PVD38124.1 - 0.0017 18.3 0.1 0.049 13.6 0.0 2.6 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 PVD38124.1 - 0.0088 16.0 7.9 0.58 10.1 0.1 3.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF1474 PF07342.11 PVD38124.1 - 0.028 14.9 0.1 0.078 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) HSP70 PF00012.20 PVD38125.1 - 2.2e-62 211.1 7.9 1.4e-46 158.9 0.2 2.0 1 1 1 2 2 2 2 Hsp70 protein FGGY_C PF02782.16 PVD38125.1 - 0.003 17.3 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain LpqV PF17301.2 PVD38125.1 - 0.02 15.1 0.1 0.1 12.8 0.1 2.1 1 1 1 2 2 2 0 Putative lipoprotein LpqV DUF883 PF05957.13 PVD38125.1 - 0.031 14.9 1.1 0.031 14.9 1.1 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) OTCace_N PF02729.21 PVD38125.1 - 0.085 12.9 0.1 5.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain PhoPQ_related PF10142.9 PVD38126.1 - 3.2e-113 378.1 0.0 3.8e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Pkinase PF00069.25 PVD38127.1 - 7e-29 101.0 0.0 8.6e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38127.1 - 8e-17 61.4 0.0 1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD38127.1 - 1.3e-09 37.3 0.1 2.2e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PVD38127.1 - 0.0014 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PVD38127.1 - 0.029 13.4 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 PVD38127.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpc4 PF05132.14 PVD38128.1 - 1.7e-25 90.2 3.9 1.7e-24 86.9 0.6 2.8 2 1 0 2 2 2 1 RNA polymerase III RPC4 tRNA-synt_1b PF00579.25 PVD38129.1 - 1.4e-72 244.5 0.0 3.8e-72 243.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) S4 PF01479.25 PVD38129.1 - 0.0037 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Exo_endo_phos_2 PF14529.6 PVD38129.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase GRAM PF02893.20 PVD38130.1 - 8.1e-15 54.7 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 PVD38130.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 PVD38130.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial PH domain FTR1 PF03239.14 PVD38131.1 - 0.0051 16.0 1.1 0.0067 15.6 1.1 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family Yip1 PF04893.17 PVD38131.1 - 0.0063 16.2 0.4 0.0089 15.8 0.4 1.1 1 0 0 1 1 1 1 Yip1 domain CD20 PF04103.15 PVD38131.1 - 0.0072 16.4 1.1 0.013 15.6 1.1 1.4 1 0 0 1 1 1 1 CD20-like family BacA PF02673.18 PVD38131.1 - 0.011 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Bacitracin resistance protein BacA Comm PF15957.5 PVD38131.1 - 0.013 15.8 0.0 0.013 15.8 0.0 1.8 3 0 0 3 3 2 0 Commissureless MgtE PF01769.16 PVD38131.1 - 0.016 15.5 1.8 0.025 15.0 1.8 1.2 1 0 0 1 1 1 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 PVD38131.1 - 0.025 14.6 0.3 0.036 14.1 0.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III L_HMGIC_fpl PF10242.9 PVD38131.1 - 0.052 13.7 2.4 0.078 13.2 2.4 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF4383 PF14325.6 PVD38131.1 - 0.062 13.6 1.5 0.088 13.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) CitMHS PF03600.16 PVD38131.1 - 0.063 12.5 0.6 0.075 12.2 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Presenilin PF01080.17 PVD38131.1 - 0.086 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Presenilin CrgA PF06781.12 PVD38131.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA ATP_synt_H PF05493.13 PVD38131.1 - 0.56 10.7 3.6 11 6.5 0.1 2.3 1 1 1 2 2 2 0 ATP synthase subunit H Gram_pos_anchor PF00746.21 PVD38131.1 - 2.1 8.4 3.8 30 4.7 0.7 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3040 PF11239.8 PVD38131.1 - 5.9 7.2 7.8 21 5.5 7.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.24 PVD38132.1 - 8e-17 61.2 31.4 4.3e-16 58.8 32.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PVD38132.1 - 2.7e-05 23.3 47.6 0.01 14.8 19.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 PVD38132.1 - 0.58 10.8 2.8 1.6 9.3 2.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lactamase_B_4 PF13691.6 PVD38133.1 - 9.6e-17 60.4 0.1 7.9e-15 54.3 0.0 3.1 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 PVD38133.1 - 1.1e-16 61.0 0.0 1.4e-12 47.5 0.9 2.7 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PVD38133.1 - 5.6e-07 29.8 0.1 4.7e-05 23.5 0.4 2.7 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily ATP-grasp PF02222.22 PVD38133.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.16 PVD38134.1 - 2.2e-13 49.9 29.2 6.6e-07 28.6 18.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TMEM154 PF15102.6 PVD38134.1 - 0.04 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.16 PVD38135.1 - 1.8e-05 23.8 9.2 2.8e-05 23.2 9.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 PVD38136.1 - 3.5e-05 22.9 5.4 4.5e-05 22.6 5.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily 7tm_1 PF00001.21 PVD38137.1 - 3e-46 157.9 13.3 3.7e-46 157.6 13.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38137.1 - 3.9e-07 29.7 14.1 9.8e-07 28.4 14.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD38137.1 - 8.4e-06 25.7 12.1 4.8e-05 23.2 12.1 1.9 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 PVD38137.1 - 1.5 8.6 15.9 4.7 6.9 15.9 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 EF_TS PF00889.19 PVD38138.1 - 3.1e-27 95.6 0.0 8.8e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor TS UBA PF00627.31 PVD38138.1 - 0.043 13.7 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Guanylate_kin PF00625.21 PVD38139.1 - 7.7e-67 224.5 0.0 8.9e-67 224.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 PVD38139.1 - 1e-06 29.0 0.0 5.4e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PVD38139.1 - 9.5e-06 26.1 0.0 2.8e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PVD38139.1 - 2.4e-05 24.6 0.0 0.00088 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PVD38139.1 - 3.8e-05 23.7 0.0 4.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 PVD38139.1 - 4.3e-05 24.1 0.1 0.00027 21.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 PVD38139.1 - 0.00045 19.4 0.0 0.00082 18.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PVD38139.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PVD38139.1 - 0.003 17.3 0.1 0.0085 15.8 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain dNK PF01712.19 PVD38139.1 - 0.0032 17.4 0.0 0.049 13.5 0.0 2.2 2 1 0 2 2 2 1 Deoxynucleoside kinase cobW PF02492.19 PVD38139.1 - 0.0044 16.6 0.0 0.026 14.1 0.0 2.0 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 PVD38139.1 - 0.0053 16.8 0.0 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PVD38139.1 - 0.0058 17.1 0.0 0.0072 16.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 PVD38139.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 PVD38139.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 PVD38139.1 - 0.0079 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 PVD38139.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 PVD38139.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 PVD38139.1 - 0.019 14.9 0.1 0.025 14.5 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 PVD38139.1 - 0.022 14.8 0.1 0.024 14.7 0.1 1.4 1 1 0 1 1 1 0 Dynamin family RHD3 PF05879.12 PVD38139.1 - 0.038 12.1 0.1 0.12 10.5 0.1 1.7 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) AAA_7 PF12775.7 PVD38139.1 - 0.04 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 PVD38139.1 - 0.044 13.5 0.0 8.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 PVD38139.1 - 0.047 13.4 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 PVD38139.1 - 0.048 12.9 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 PVD38139.1 - 0.067 12.9 0.1 0.44 10.2 0.0 2.1 1 1 2 3 3 3 0 AAA domain Septin PF00735.18 PVD38139.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_17 PF13207.6 PVD38139.1 - 0.099 13.1 0.0 0.37 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 PVD38139.1 - 0.11 12.9 0.1 0.51 10.8 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PVD38139.1 - 0.15 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3970 PF13113.6 PVD38139.1 - 0.17 12.1 1.4 2.4 8.4 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3970) AAA_23 PF13476.6 PVD38139.1 - 0.34 11.4 3.0 1 9.8 3.0 1.9 1 1 0 1 1 1 0 AAA domain APG6 PF04111.12 PVD38140.1 - 1.2e-43 149.1 5.0 9.9e-30 103.8 0.5 2.4 1 1 1 2 2 2 2 Apg6 BARA domain APG6_N PF17675.1 PVD38140.1 - 2.5e-27 96.0 30.7 4.3e-27 95.2 30.7 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BH3 PF15285.6 PVD38140.1 - 2.8e-13 49.3 0.1 6.8e-13 48.1 0.1 1.7 2 0 0 2 2 2 1 Beclin-1 BH3 domain, Bcl-2-interacting zf-C4H2 PF10146.9 PVD38140.1 - 0.03 14.6 4.9 0.051 13.9 4.9 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_11 PF13086.6 PVD38140.1 - 0.33 10.7 3.7 0.49 10.1 3.7 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 PVD38140.1 - 1.9 8.0 6.6 2.9 7.4 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3042 PF11240.8 PVD38141.1 - 0.041 13.9 0.1 0.55 10.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3042) Tim44 PF04280.15 PVD38142.1 - 5.1e-06 26.7 0.0 7.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain Cupin_8 PF13621.6 PVD38143.1 - 1.2e-23 84.1 0.1 6.3e-23 81.8 0.0 2.2 2 1 0 2 2 2 1 Cupin-like domain RRM_1 PF00076.22 PVD38143.1 - 8.6e-13 47.9 0.1 1.2e-06 28.2 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_4 PF08007.12 PVD38143.1 - 0.00034 20.2 0.0 0.00057 19.4 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PVD38143.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase UQ_con PF00179.26 PVD38144.1 - 3.1e-16 59.3 0.0 4.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2 PF00096.26 PVD38146.1 - 1.1e-13 50.8 26.6 0.00035 20.9 5.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PVD38146.1 - 3e-07 30.6 5.0 3e-07 30.6 5.0 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PVD38146.1 - 2.8e-06 27.7 23.7 0.058 14.3 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3850 PF12961.7 PVD38146.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) FOXP-CC PF16159.5 PVD38146.1 - 0.099 13.3 6.4 2.3 8.9 1.1 2.6 2 1 0 2 2 2 0 FOXP coiled-coil domain SDA1 PF05285.12 PVD38146.1 - 0.13 11.6 6.6 0.15 11.4 6.6 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 PVD38146.1 - 0.32 8.7 3.4 0.45 8.2 3.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 PVD38146.1 - 0.51 10.4 7.2 0.71 9.9 7.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-C2H2_aberr PF17017.5 PVD38146.1 - 0.62 10.2 7.5 1.1 9.3 0.5 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 PVD38146.1 - 1.1 9.3 10.8 4.5 7.4 2.4 2.5 2 0 0 2 2 2 0 BED zinc finger Nop14 PF04147.12 PVD38146.1 - 1.7 6.8 11.8 2.1 6.5 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family IBR PF01485.21 PVD38146.1 - 3.5 7.9 7.4 30 4.9 7.4 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain BUD22 PF09073.10 PVD38146.1 - 3.6 6.8 8.3 4.6 6.5 8.3 1.1 1 0 0 1 1 1 0 BUD22 zf-H2C2_5 PF13909.6 PVD38146.1 - 7.2 6.5 21.2 0.33 10.7 0.3 4.2 3 1 0 3 3 3 0 C2H2-type zinc-finger domain PyrI_C PF02748.15 PVD38146.1 - 9.1 6.3 6.3 0.84 9.6 1.7 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain MbtH PF03621.13 PVD38147.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 MbtH-like protein TNFR_c6 PF00020.18 PVD38148.1 - 1.1e-25 89.7 37.5 3.8e-11 43.2 7.6 4.2 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region TNFR_16_TM PF18422.1 PVD38148.1 - 1.4e-07 31.3 0.1 2.7e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain Death PF00531.22 PVD38148.1 - 0.00046 20.3 0.0 0.00088 19.4 0.0 1.4 1 0 0 1 1 1 1 Death domain Recep_L_domain PF01030.24 PVD38151.1 - 1.5e-45 153.9 2.1 1.7e-23 82.8 0.2 2.5 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 PVD38151.1 - 7.4e-34 116.8 120.3 3.1e-25 88.8 34.3 5.5 2 1 3 5 5 5 5 Furin-like cysteine rich region GF_recep_IV PF14843.6 PVD38151.1 - 4.4e-31 107.4 117.7 5e-20 71.6 32.7 6.6 2 2 4 6 6 6 5 Growth factor receptor domain IV 7tm_1 PF00001.21 PVD38155.1 - 2.2e-37 128.8 7.0 2.9e-37 128.4 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD38155.1 - 0.00021 21.0 15.7 0.00036 20.3 15.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD38155.1 - 0.00037 20.0 12.4 0.00062 19.2 12.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD38155.1 - 0.0012 18.6 12.7 0.0041 16.9 12.7 1.7 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 PVD38156.1 - 9.7e-06 25.1 10.6 1.2e-05 24.8 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SAM_1 PF00536.30 PVD38157.1 - 2.7e-13 50.1 0.2 4.7e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PVD38157.1 - 4.5e-09 36.3 0.2 9.6e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_C PF14360.6 PVD38157.1 - 3.8e-06 27.3 1.4 3.8e-06 27.3 1.4 2.9 3 1 0 3 3 3 1 PAP2 superfamily C-terminal SAM_3 PF18016.1 PVD38157.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PVD38157.1 - 0.033 14.1 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Porin_3 PF01459.22 PVD38158.1 - 6.6e-83 278.3 9.9 7.5e-83 278.1 9.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Filamin PF00630.19 PVD38159.1 - 1e-14 55.2 0.0 1.5e-14 54.6 0.0 1.3 1 1 0 1 1 1 1 Filamin/ABP280 repeat Filamin PF00630.19 PVD38160.1 - 2.6e-82 272.3 1.0 3.4e-13 50.3 0.0 7.2 7 0 0 7 7 7 7 Filamin/ABP280 repeat Y_Y_Y PF07495.13 PVD38160.1 - 2.9e-10 39.9 1.1 0.36 10.8 0.1 5.5 5 0 0 5 5 5 3 Y_Y_Y domain EMP24_GP25L PF01105.24 PVD38160.1 - 0.00088 19.3 0.0 0.082 12.8 0.0 3.1 2 1 0 3 3 3 1 emp24/gp25L/p24 family/GOLD 7TM_GPCR_Srw PF10324.9 PVD38162.1 - 0.00052 19.4 10.3 0.0011 18.4 10.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw PreAtp-grasp PF18604.1 PVD38162.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain DUF3923 PF13061.6 PVD38162.1 - 0.13 12.3 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) DUF5565 PF17720.1 PVD38162.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) zf-HC5HC2H PF13771.6 PVD38163.1 - 9.7e-14 51.4 9.1 3e-13 49.8 9.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PVD38163.1 - 1.6e-06 28.3 5.5 4.1e-06 26.9 5.5 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain FANCL_C PF11793.8 PVD38163.1 - 6.6 7.0 8.6 1.1 9.5 3.7 2.3 3 0 0 3 3 3 0 FANCL C-terminal domain Mto2_bdg PF12808.7 PVD38164.1 - 0.028 14.7 0.3 0.028 14.7 0.3 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_Maf PF03131.17 PVD38165.1 - 4.7e-31 107.2 8.7 6.3e-31 106.8 8.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 PVD38165.1 - 0.00011 22.3 11.0 0.00026 21.0 11.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2046 PF09755.9 PVD38165.1 - 0.00052 19.3 1.6 0.00052 19.3 1.6 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) JIP_LZII PF16471.5 PVD38165.1 - 0.0045 17.1 6.8 0.0075 16.4 2.6 2.3 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II DivIC PF04977.15 PVD38165.1 - 0.0058 16.4 1.9 0.0058 16.4 1.9 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_2 PF07716.15 PVD38165.1 - 0.0083 16.2 9.0 0.0083 16.2 9.0 2.3 1 1 1 2 2 2 1 Basic region leucine zipper DUF1192 PF06698.11 PVD38165.1 - 0.016 15.3 1.5 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_TATA_bd PF12325.8 PVD38165.1 - 0.034 14.4 3.4 0.034 14.4 3.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 PVD38165.1 - 0.056 12.0 1.7 0.057 12.0 1.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 PVD38165.1 - 0.23 10.0 5.3 0.24 9.9 5.3 1.1 1 0 0 1 1 1 0 Macoilin family HALZ PF02183.18 PVD38165.1 - 0.3 11.4 6.8 0.12 12.6 2.1 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 PVD38165.1 - 0.38 9.8 6.2 0.52 9.3 6.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 PVD38165.1 - 0.87 10.1 9.0 0.43 11.1 3.2 2.3 1 1 2 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 PVD38165.1 - 1.2 9.7 10.8 3.8 8.1 10.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region GPS2_interact PF15784.5 PVD38165.1 - 1.2 9.6 6.5 1.6 9.2 1.3 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sec62 PF03839.16 PVD38166.1 - 4.9 6.6 9.5 5.3 6.5 9.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Rsc14 PF08586.10 PVD38166.1 - 8.8 7.2 6.3 6.3 7.7 5.1 1.3 1 1 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit ORC3_N PF07034.11 PVD38167.1 - 0.2 10.7 0.1 0.71 8.9 0.0 1.7 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus TANGO2 PF05742.12 PVD38168.1 - 0.0072 16.4 2.0 0.0087 16.1 2.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 SBD PF17882.1 PVD38168.1 - 0.049 13.5 0.4 0.13 12.0 0.4 1.7 1 1 1 2 2 2 0 OAA-family lectin sugar binding domain NUDE_C PF04880.13 PVD38169.1 - 2.4e-36 125.9 0.2 2.4e-36 125.9 0.2 2.9 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region Spc7 PF08317.11 PVD38169.1 - 0.0021 17.0 31.3 0.045 12.6 15.9 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DMPK_coil PF08826.10 PVD38169.1 - 0.0042 17.1 4.0 0.0042 17.1 4.0 4.9 2 1 3 5 5 4 1 DMPK coiled coil domain like TPR_MLP1_2 PF07926.12 PVD38169.1 - 0.006 16.7 36.7 0.13 12.3 11.4 3.2 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 PVD38169.1 - 0.0082 16.5 18.6 0.0082 16.5 18.6 2.9 2 1 1 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin_2 PF01920.20 PVD38169.1 - 0.01 15.8 5.8 0.01 15.8 5.8 4.1 1 1 2 3 3 3 1 Prefoldin subunit DUF3584 PF12128.8 PVD38169.1 - 0.01 13.4 19.3 0.015 12.9 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 PVD38169.1 - 0.013 15.0 15.5 0.013 15.0 15.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Dynamitin PF04912.14 PVD38169.1 - 0.015 14.7 23.6 0.14 11.5 1.0 2.5 1 1 1 2 2 2 0 Dynamitin Tropomyosin_1 PF12718.7 PVD38169.1 - 0.028 14.6 34.6 0.68 10.1 33.8 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 PVD38169.1 - 0.029 13.7 26.2 1.6 8.0 11.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 PVD38169.1 - 0.051 14.1 22.7 0.33 11.4 14.3 3.3 2 1 0 3 3 3 0 Spectrin repeat Fez1 PF06818.15 PVD38169.1 - 0.067 13.6 25.1 0.17 12.3 18.5 2.2 1 1 1 2 2 2 0 Fez1 CALCOCO1 PF07888.11 PVD38169.1 - 0.075 11.9 25.7 0.1 11.4 25.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IFT57 PF10498.9 PVD38169.1 - 0.076 12.0 20.6 0.0086 15.1 15.3 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 PVD38169.1 - 0.083 12.2 20.0 0.94 8.8 13.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 PVD38169.1 - 0.096 13.1 15.0 2.7 8.4 1.5 4.9 3 1 2 5 5 4 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 PVD38169.1 - 0.12 12.4 33.8 0.058 13.5 18.1 3.9 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Tektin PF03148.14 PVD38169.1 - 0.16 10.7 26.5 0.024 13.4 10.2 3.0 1 1 1 2 2 2 0 Tektin family TelA PF05816.11 PVD38169.1 - 0.18 10.9 14.1 0.13 11.3 11.6 1.8 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Med3 PF11593.8 PVD38169.1 - 0.19 10.9 2.7 0.26 10.4 2.3 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal LCIB_C_CA PF18599.1 PVD38169.1 - 0.23 10.8 1.4 0.34 10.2 1.4 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF603 PF04645.12 PVD38169.1 - 0.25 11.0 7.7 0.14 11.8 5.2 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF603 Fib_alpha PF08702.10 PVD38169.1 - 0.27 11.4 18.2 0.33 11.2 8.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Flagellin_N PF00669.20 PVD38169.1 - 0.29 11.2 5.6 0.49 10.5 2.7 2.3 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DASH_Dam1 PF08653.10 PVD38169.1 - 0.32 10.8 3.0 39 4.2 0.1 3.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 KASH_CCD PF14662.6 PVD38169.1 - 0.38 10.6 33.7 1.4 8.7 23.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 PVD38169.1 - 0.42 10.7 29.4 0.11 12.6 14.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.8 PVD38169.1 - 0.53 9.9 19.9 0.21 11.2 12.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) WEMBL PF05701.11 PVD38169.1 - 0.54 8.9 27.9 1.2 7.7 27.9 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light MAD PF05557.13 PVD38169.1 - 0.58 8.4 28.3 0.83 7.9 28.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cep57_MT_bd PF06657.13 PVD38169.1 - 0.59 10.6 23.7 1.5 9.3 1.2 3.6 2 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF745 PF05335.13 PVD38169.1 - 0.6 9.8 18.9 0.33 10.6 15.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.9 PVD38169.1 - 0.61 9.1 21.2 12 4.9 22.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 PVD38169.1 - 0.72 10.1 34.2 1.6 8.9 15.2 3.0 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Cytochrom_B562 PF07361.11 PVD38169.1 - 0.81 10.4 12.6 0.43 11.3 5.8 2.9 1 1 1 3 3 2 0 Cytochrome b562 FUSC PF04632.12 PVD38169.1 - 0.82 8.1 5.1 1.1 7.7 5.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 PVD38169.1 - 0.88 9.9 20.8 0.081 13.2 10.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 PVD38169.1 - 0.92 9.0 29.1 0.063 12.8 10.7 2.4 1 1 1 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 PVD38169.1 - 1 9.9 40.9 37 4.8 36.8 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 PVD38169.1 - 1 9.4 18.1 0.42 10.6 7.7 2.4 1 1 1 2 2 2 0 Laminin Domain II HMMR_N PF15905.5 PVD38169.1 - 1.1 8.7 32.5 1 8.8 18.9 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal WXG100 PF06013.12 PVD38169.1 - 1.1 9.6 9.8 0.44 10.8 2.3 3.1 3 1 0 3 3 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 PVD38169.1 - 1.2 9.1 13.5 0.54 10.3 5.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 PVD38169.1 - 1.2 10.0 29.4 14 6.6 17.1 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 PVD38169.1 - 1.4 9.1 24.8 4.1 7.7 10.2 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PI_PP_I PF18363.1 PVD38169.1 - 1.5 9.1 4.1 6 7.1 0.3 2.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Spc24 PF08286.11 PVD38169.1 - 1.5 9.1 28.3 0.17 12.1 4.7 4.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Baculo_PEP_C PF04513.12 PVD38169.1 - 1.6 8.8 8.1 0.79 9.8 3.2 2.6 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 PVD38169.1 - 1.7 7.9 32.3 1.6 8.0 15.4 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.12 PVD38169.1 - 2.1 7.6 21.3 0.48 9.7 2.0 4.0 2 1 2 4 4 4 0 CASP C terminal Syntaxin_2 PF14523.6 PVD38169.1 - 2.8 8.4 17.6 0.38 11.1 5.1 3.0 1 1 2 3 3 3 0 Syntaxin-like protein Rootletin PF15035.6 PVD38169.1 - 2.8 7.9 30.8 0.55 10.2 15.2 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.11 PVD38169.1 - 2.9 8.5 22.4 0.49 11.0 5.7 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF16 PF01519.16 PVD38169.1 - 3.4 8.2 18.0 0.59 10.6 10.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Bacillus_HBL PF05791.11 PVD38169.1 - 3.7 7.3 13.7 2.7 7.8 4.3 2.9 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.6 PVD38169.1 - 3.7 8.0 24.5 0.23 11.9 10.1 3.6 1 1 2 3 3 3 0 Snapin/Pallidin Fzo_mitofusin PF04799.13 PVD38169.1 - 4.1 6.9 18.7 0.27 10.8 8.7 2.8 1 1 1 2 2 2 0 fzo-like conserved region SpecificRecomb PF10136.9 PVD38169.1 - 5 5.3 5.3 6.3 5.0 5.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase Prominin PF05478.11 PVD38169.1 - 5.1 4.9 14.2 0.65 7.9 8.5 1.8 1 1 1 2 2 2 0 Prominin HIP1_clath_bdg PF16515.5 PVD38169.1 - 5.7 7.6 27.7 5.2 7.7 15.3 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GIT_CC PF16559.5 PVD38169.1 - 5.8 6.9 15.7 0.45 10.4 1.5 3.7 3 1 1 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lectin_N PF03954.14 PVD38169.1 - 6.9 6.4 14.0 1.8 8.3 3.3 3.1 2 1 2 4 4 3 0 Hepatic lectin, N-terminal domain PilJ PF13675.6 PVD38169.1 - 7.6 6.6 9.1 3.5 7.7 3.5 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FliD_C PF07195.12 PVD38169.1 - 7.8 5.8 10.9 4.4 6.7 5.6 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Jnk-SapK_ap_N PF09744.9 PVD38169.1 - 8 6.7 36.4 5.4 7.2 17.9 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Trimer_CC PF08954.11 PVD38169.1 - 8.1 6.1 12.6 13 5.5 0.7 4.0 3 1 0 3 3 3 0 Trimerisation motif KxDL PF10241.9 PVD38169.1 - 8.2 6.8 17.0 1.8 8.9 2.3 3.8 1 1 2 4 4 4 0 Uncharacterized conserved protein Serine_rich PF08824.10 PVD38169.1 - 8.3 6.4 13.6 3.9 7.5 5.5 2.9 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF948 PF06103.11 PVD38169.1 - 8.5 6.7 7.7 5 7.5 1.9 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 PVD38169.1 - 8.6 6.3 24.0 6.7 6.7 3.7 4.4 2 1 3 5 5 4 0 Prefoldin subunit DUF641 PF04859.12 PVD38169.1 - 9.6 6.6 21.9 0.54 10.6 4.4 3.5 1 1 2 4 4 4 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 PVD38169.1 - 10 6.6 23.8 0.25 11.7 5.2 4.1 2 1 2 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DNA_pol_E_B PF04042.16 PVD38170.1 - 1.9e-45 154.9 0.0 3e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 PVD38170.1 - 7.7e-40 136.0 0.0 1.6e-39 135.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain HLH PF00010.26 PVD38172.1 - 3.4e-17 62.1 2.3 7.4e-17 61.1 2.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4636 PF15468.6 PVD38172.1 - 0.18 11.5 5.1 0.24 11.0 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4661 PF15576.6 PVD38172.1 - 9.3 6.1 9.2 20 5.0 9.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Aldo_ket_red PF00248.21 PVD38177.1 - 5.4e-44 150.6 0.0 1.6e-41 142.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PVD38178.1 - 4e-48 164.1 0.0 6.1e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family KASH_CCD PF14662.6 PVD38179.1 - 0.0012 18.7 9.4 0.0012 18.7 9.4 3.2 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 PVD38179.1 - 0.002 18.2 18.0 0.002 18.2 18.0 4.4 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 PVD38179.1 - 0.0044 17.1 33.1 0.057 13.5 11.7 3.1 2 1 2 4 4 4 3 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 PVD38179.1 - 0.01 16.4 3.3 0.01 16.4 3.3 4.6 2 1 2 4 4 4 0 Initiation control protein YabA bZIP_1 PF00170.21 PVD38179.1 - 0.035 14.2 0.3 0.035 14.2 0.3 5.9 4 3 2 6 6 5 0 bZIP transcription factor BST2 PF16716.5 PVD38179.1 - 0.087 13.4 29.7 0.23 12.1 13.2 3.8 2 1 0 3 3 3 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 PVD38179.1 - 0.11 12.7 36.8 0.18 12.0 10.4 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 PVD38179.1 - 0.12 12.4 35.4 0.13 12.4 5.8 4.5 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF4618 PF15397.6 PVD38179.1 - 0.14 11.6 27.1 0.69 9.3 10.9 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) TSC22 PF01166.18 PVD38179.1 - 0.42 11.0 0.1 0.42 11.0 0.1 5.4 5 1 1 6 6 6 0 TSC-22/dip/bun family DUF3153 PF11353.8 PVD38179.1 - 0.48 10.0 4.7 0.32 10.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) ZapB PF06005.12 PVD38179.1 - 0.52 10.8 36.8 0.15 12.5 4.3 5.8 2 1 2 4 4 4 0 Cell division protein ZapB HisKA_3 PF07730.13 PVD38179.1 - 1 9.9 12.4 2.7 8.6 0.4 4.0 2 1 2 4 4 3 0 Histidine kinase EzrA PF06160.12 PVD38179.1 - 2.4 6.3 28.5 0.34 9.0 23.6 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 PVD38179.1 - 2.5 8.2 21.9 0.16 12.0 5.3 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) GPS2_interact PF15784.5 PVD38179.1 - 2.8 8.4 13.3 0.37 11.3 2.2 4.2 3 1 1 4 4 4 0 G-protein pathway suppressor 2-interacting domain DUF948 PF06103.11 PVD38179.1 - 4.5 7.6 11.6 8.1 6.8 0.1 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 PVD38179.1 - 4.8 6.9 33.5 4 7.2 6.2 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) Csm1_N PF18504.1 PVD38179.1 - 5.3 7.4 30.6 20 5.6 0.2 5.3 3 2 3 6 6 6 0 Csm1 N-terminal domain GAS PF13851.6 PVD38179.1 - 6.6 6.0 34.9 2.2 7.6 16.8 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 PVD38179.1 - 6.9 7.6 32.6 0.84 10.6 9.2 4.1 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 PVD38179.1 - 6.9 5.9 23.4 2.7 7.2 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) GLE1 PF07817.13 PVD38179.1 - 7.1 5.8 6.1 0.93 8.6 0.9 2.1 1 1 1 2 2 2 0 GLE1-like protein TACC_C PF05010.14 PVD38179.1 - 7.3 6.3 29.9 0.62 9.8 19.0 3.0 2 1 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 PVD38179.1 - 7.5 5.3 39.0 2.8 6.7 19.2 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 PVD38179.1 - 9 7.0 30.8 0.12 13.1 7.3 4.2 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CH PF00307.31 PVD38180.1 - 1.7e-17 63.6 0.9 6.4e-09 36.0 0.1 3.2 2 1 0 2 2 2 2 Calponin homology (CH) domain Kelch_1 PF01344.25 PVD38181.1 - 4.2e-88 288.7 23.0 2.1e-15 56.0 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PVD38181.1 - 2.1e-41 138.9 6.5 4.4e-07 30.0 0.1 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 PVD38181.1 - 1.3e-34 118.3 3.0 1.3e-34 118.3 3.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 PVD38181.1 - 1.8e-32 111.8 1.0 3.9e-32 110.8 1.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PVD38181.1 - 5e-26 90.4 13.0 4.8e-06 26.7 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 PVD38181.1 - 1.1e-24 85.4 13.9 1.8e-06 27.7 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PVD38181.1 - 1.7e-23 82.4 5.8 2.3e-05 24.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 PVD38181.1 - 0.00013 21.9 10.4 2 8.5 0.1 5.4 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 PVD38181.1 - 0.0017 18.8 17.3 1.4 9.5 0.2 5.3 5 0 0 5 5 5 2 PQQ-like domain DUF3342 PF11822.8 PVD38181.1 - 0.11 12.6 0.5 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) AP1AR PF15745.5 PVD38182.1 - 4.3e-31 108.6 14.2 5.9e-31 108.1 14.2 1.1 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein SUIM_assoc PF16619.5 PVD38182.1 - 0.0021 18.1 0.4 0.015 15.4 0.0 2.5 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 AMP-binding PF00501.28 PVD38183.1 - 9.3e-50 169.4 0.0 1.6e-29 102.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PVD38183.1 - 0.00034 21.5 0.0 0.0029 18.6 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ig_3 PF13927.6 PVD38184.1 - 4.4e-16 59.2 0.4 1e-09 38.8 0.1 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 PVD38184.1 - 4.1e-15 55.6 0.0 5.9e-11 42.3 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Kazal_2 PF07648.15 PVD38184.1 - 4.3e-09 36.4 1.1 1.7e-08 34.5 1.1 2.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.6 PVD38184.1 - 4.5e-08 33.3 0.0 0.00047 20.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Kazal_1 PF00050.21 PVD38184.1 - 1.1e-05 25.3 4.7 3.6e-05 23.7 4.7 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 PVD38184.1 - 0.0039 17.6 0.4 0.0039 17.6 0.4 2.0 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PVD38184.1 - 0.029 14.3 0.1 8.8 6.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 PVD38184.1 - 0.049 13.2 0.1 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 EF hand Ig_6 PF18452.1 PVD38184.1 - 0.1 12.2 0.0 0.86 9.2 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain DUF2722 PF10846.8 PVD38184.1 - 0.12 11.3 12.8 0.2 10.6 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CBM_5_12 PF02839.14 PVD38184.1 - 0.67 10.6 5.2 1.3 9.7 0.5 3.1 3 0 0 3 3 2 0 Carbohydrate binding domain EB PF01683.18 PVD38184.1 - 7 7.0 13.2 0.34 11.2 6.1 2.5 2 1 1 3 3 3 0 EB module UMPH-1 PF05822.12 PVD38186.1 - 8.9e-92 307.1 1.6 1e-91 306.9 1.6 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 PVD38186.1 - 0.012 16.0 0.1 0.023 15.1 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 PVD38187.1 - 8.4e-40 136.3 0.0 1.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38187.1 - 5.1e-26 91.7 0.0 7.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD38187.1 - 2.5e-05 24.3 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD38187.1 - 0.085 12.2 0.0 0.46 9.8 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 PVD38188.1 - 7.4e-40 136.5 0.0 1.2e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38188.1 - 3.7e-26 92.1 0.0 4.7e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD38188.1 - 1.5e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PVD38188.1 - 0.017 14.5 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2099 PF09872.9 PVD38188.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Eno-Rase_NADH_b PF12242.8 PVD38188.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PP2C PF00481.21 PVD38189.1 - 3.3e-36 125.2 0.1 8.2e-34 117.4 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C adh_short PF00106.25 PVD38189.1 - 7e-26 90.9 0.0 1.8e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38189.1 - 7.1e-13 48.7 0.0 3.6e-12 46.4 0.0 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PP2C_2 PF13672.6 PVD38189.1 - 2e-05 24.4 0.0 9.5e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C KR PF08659.10 PVD38189.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 KR domain Cullin_binding PF03556.15 PVD38190.1 - 1.5e-31 109.3 0.1 2.4e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Cullin binding TGF_beta PF00019.20 PVD38191.1 - 4.5e-17 62.9 0.1 7.6e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain IRK_C PF17655.1 PVD38193.1 - 5.8e-45 153.0 0.0 1.2e-44 152.0 0.0 1.5 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PVD38193.1 - 4.8e-43 146.4 0.6 8e-43 145.6 0.6 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PVD38193.1 - 0.0038 17.2 6.6 0.011 15.7 6.6 1.8 1 1 0 1 1 1 1 Ion channel Bax1-I PF01027.20 PVD38193.1 - 0.11 12.3 5.1 0.18 11.6 5.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3522 PF12036.8 PVD38193.1 - 0.11 12.7 1.0 0.2 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) Ins_beta PF03488.14 PVD38194.1 - 0.037 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type IRK_C PF17655.1 PVD38195.1 - 4.6e-75 251.0 0.0 6.4e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PVD38195.1 - 1.5e-62 209.5 2.5 2.2e-62 209.0 2.5 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PVD38195.1 - 0.00045 20.1 1.1 0.00083 19.3 1.1 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PVD38195.1 - 0.0052 16.1 1.8 0.0071 15.6 1.8 1.1 1 0 0 1 1 1 1 Ion transport protein TrkH PF02386.16 PVD38195.1 - 0.11 10.9 1.1 0.16 10.4 1.1 1.1 1 0 0 1 1 1 0 Cation transport protein AgrB PF04647.15 PVD38195.1 - 0.3 10.4 2.5 1.4 8.2 0.2 2.1 2 0 0 2 2 2 0 Accessory gene regulator B DUF4128 PF13554.6 PVD38200.1 - 0.14 12.2 0.0 4.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function Pyr_redox_3 PF13738.6 PVD38202.1 - 1.9e-35 122.6 0.0 3.2e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD38202.1 - 8e-10 38.4 0.0 1.2e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PVD38202.1 - 1.4e-08 34.3 0.0 6.7e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 PVD38202.1 - 5.9e-08 32.3 0.0 6.4e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FMO-like PF00743.19 PVD38202.1 - 3.2e-07 29.2 0.0 4.7e-05 22.0 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like HI0933_like PF03486.14 PVD38202.1 - 2.5e-05 23.2 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 PVD38202.1 - 0.00018 22.0 0.0 1.3 9.7 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD38202.1 - 0.00032 20.9 0.0 0.00083 19.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD38202.1 - 0.0062 16.2 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase YaiA PF16362.5 PVD38202.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 YaiA protein FAD_binding_2 PF00890.24 PVD38202.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PsbM PF05151.12 PVD38202.1 - 0.79 9.6 3.1 1.4 8.7 3.1 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Pyr_redox_3 PF13738.6 PVD38203.1 - 8.3e-40 136.9 0.0 1.3e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PVD38203.1 - 3e-12 46.4 0.0 5e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 PVD38203.1 - 4.2e-07 28.8 0.0 5.5e-06 25.1 0.0 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 PVD38203.1 - 6e-07 28.9 0.0 1.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 PVD38203.1 - 1.5e-06 27.7 0.0 0.00062 19.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 PVD38203.1 - 0.00041 19.2 0.0 0.86 8.2 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 PVD38203.1 - 0.00079 19.6 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PVD38203.1 - 0.0024 18.4 0.0 3.1 8.4 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PVD38203.1 - 0.0034 17.0 0.0 0.66 9.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase YaiA PF16362.5 PVD38203.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 YaiA protein Fibrinogen_C PF00147.18 PVD38204.1 - 2.2e-26 93.0 0.9 3.4e-26 92.4 0.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD38204.1 - 5.3e-06 26.3 4.9 5.3e-06 26.3 4.9 1.9 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 PVD38204.1 - 0.0017 18.2 2.3 0.0035 17.2 1.1 2.3 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 PVD38204.1 - 0.015 15.1 2.5 0.044 13.6 2.5 1.8 1 0 0 1 1 1 0 PAN-like domain Flu_C_NS2 PF03555.14 PVD38205.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) N_BRCA1_IG PF16158.5 PVD38208.1 - 3.6e-21 75.8 0.0 9.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 PVD38208.1 - 9.6e-08 31.7 6.1 2e-07 30.7 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 PVD38208.1 - 2.7e-07 30.4 0.8 8.8e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 PB1 domain CARDB PF07705.11 PVD38208.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 CARDB tRNA-synt_1g PF09334.11 PVD38208.1 - 0.083 11.6 1.1 0.15 10.8 1.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) C1_2 PF03107.16 PVD38208.1 - 0.76 10.1 9.0 1.8 9.0 9.0 1.6 1 0 0 1 1 1 0 C1 domain Cas1_AcylT PF07779.12 PVD38209.1 - 3.5e-210 698.9 30.2 4.4e-210 698.6 30.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Oxidored_molyb PF00174.19 PVD38210.1 - 0.18 11.4 0.0 0.82 9.3 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain UBA_4 PF14555.6 PVD38212.1 - 6.8e-09 35.4 0.2 1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 PVD38212.1 - 0.0011 18.6 1.2 0.0032 17.1 0.4 2.0 2 0 0 2 2 2 1 TAP C-terminal domain ThiF PF00899.21 PVD38212.1 - 0.0093 15.3 0.1 0.011 15.2 0.1 1.0 1 0 0 1 1 1 1 ThiF family zf-C3HC4_3 PF13920.6 PVD38213.1 - 2.9e-13 49.4 10.5 2.9e-13 49.4 10.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD38213.1 - 3.8e-07 29.9 9.9 1.1e-06 28.4 9.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PVD38213.1 - 7.4e-05 23.0 12.4 7.4e-05 23.0 12.4 2.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PVD38213.1 - 0.024 14.6 9.9 0.058 13.4 9.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PVD38213.1 - 0.034 14.0 13.1 0.074 12.9 13.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PVD38213.1 - 1.3 8.9 9.6 3.9 7.3 9.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PVD38213.1 - 2.5 7.9 8.5 0.13 12.0 1.6 2.5 2 1 0 2 2 2 0 RING-like zinc finger 7tm_1 PF00001.21 PVD38215.1 - 3.9e-17 62.5 22.2 5.5e-17 61.9 22.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VMA21 PF09446.10 PVD38215.1 - 0.00045 20.3 1.3 0.00045 20.3 1.3 2.9 3 0 0 3 3 3 1 VMA21-like domain 7TM_GPCR_Srx PF10328.9 PVD38215.1 - 0.0057 16.3 16.6 0.0057 16.3 16.6 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MitoNEET_N PF10660.9 PVD38216.1 - 1.1e-23 83.0 0.1 1.4e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 PVD38216.1 - 1.7e-09 37.8 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF4639 PF15479.6 PVD38217.1 - 2.6e-41 142.3 6.8 4.9e-39 134.8 0.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4639) Enkurin PF13864.6 PVD38218.1 - 8.9e-27 93.4 2.8 8.9e-27 93.4 2.8 2.4 3 0 0 3 3 3 1 Calmodulin-binding LELP1 PF15042.6 PVD38218.1 - 0.093 13.1 2.0 0.19 12.2 2.0 1.5 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 SF-assemblin PF06705.11 PVD38218.1 - 0.54 9.6 4.5 0.24 10.7 0.4 2.1 2 0 0 2 2 2 0 SF-assemblin/beta giardin SPT16 PF08644.11 PVD38218.1 - 1.2 9.3 4.9 0.91 9.7 0.3 2.4 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) ABC2_membrane PF01061.24 PVD38219.1 - 7.4e-40 136.6 27.6 1.1e-39 136.1 27.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PVD38219.1 - 1.6e-21 77.2 0.0 2.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PVD38219.1 - 8.8e-08 32.3 0.1 0.007 16.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PVD38219.1 - 8.6e-05 22.1 0.0 0.19 11.1 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 PVD38219.1 - 0.00021 20.5 37.2 0.00095 18.4 37.1 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 PVD38219.1 - 0.0071 16.1 0.3 0.017 14.9 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PVD38219.1 - 0.01 16.4 0.1 0.016 15.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PVD38219.1 - 0.12 12.4 0.4 0.3 11.2 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 PVD38219.1 - 0.2 11.6 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase Pkinase PF00069.25 PVD38220.1 - 3.6e-49 167.5 0.0 4.9e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38220.1 - 1.6e-33 116.1 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD38220.1 - 4.8e-08 32.7 0.0 8.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PVD38220.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD38220.1 - 0.011 15.7 0.3 0.039 13.9 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family BMP2K_C PF15282.6 PVD38220.1 - 0.011 15.6 1.1 0.025 14.4 1.1 1.5 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Pox_ser-thr_kin PF05445.11 PVD38220.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF966 PF06136.13 PVD38221.1 - 0.51 10.0 9.3 0.18 11.5 6.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF966) MADF_DNA_bdg PF10545.9 PVD38223.1 - 1.1e-22 80.1 1.3 2.3e-22 79.1 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 PVD38223.1 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_4 PF13837.6 PVD38223.1 - 0.0046 17.3 1.3 0.011 16.1 1.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PVD38223.1 - 0.0086 16.1 0.3 0.021 14.9 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Radical_SAM PF04055.21 PVD38224.1 - 1.2e-09 38.8 0.0 4.3e-08 33.7 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily TFCD_C PF12612.8 PVD38225.1 - 3.4e-62 209.6 2.1 1.5e-61 207.6 0.1 3.1 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 PVD38225.1 - 2.8e-08 33.3 11.2 0.76 10.2 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 PVD38225.1 - 7e-06 26.4 7.4 16 6.1 0.0 8.2 8 1 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 PVD38225.1 - 4.4e-05 23.8 0.5 6.3 7.3 0.0 5.4 6 0 0 6 6 6 2 HEAT repeats Cnd1 PF12717.7 PVD38225.1 - 0.002 18.2 0.0 1.3 9.0 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PVD38225.1 - 0.0025 18.4 0.8 27 5.4 0.0 5.5 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Rif1_N PF12231.8 PVD38225.1 - 0.03 13.3 0.1 0.064 12.2 0.1 1.4 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Phage_hub_GP28 PF11110.8 PVD38225.1 - 0.11 12.4 0.0 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Baseplate hub distal subunit P3A PF08727.11 PVD38227.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like Fam20C PF06702.12 PVD38228.1 - 1.3e-62 211.5 1.5 3.6e-62 210.0 1.5 1.6 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 Gemini_mov PF01708.16 PVD38229.1 - 0.17 11.6 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Somatomedin_B PF01033.17 PVD38229.1 - 2.7 8.5 16.3 5.8 7.4 16.3 1.6 1 0 0 1 1 1 0 Somatomedin B domain YrhC PF14143.6 PVD38230.1 - 0.19 11.9 0.2 0.46 10.6 0.2 1.6 1 0 0 1 1 1 0 YrhC-like protein OATP PF03137.20 PVD38231.1 - 2.7e-115 385.7 8.1 4e-115 385.2 8.1 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 PVD38231.1 - 3.1e-15 56.0 27.0 1.5e-12 47.1 23.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 PVD38231.1 - 2.4e-05 24.4 1.0 2.4e-05 24.4 1.0 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PVD38231.1 - 0.00048 20.1 0.3 0.0021 18.1 0.3 2.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Romo1 PF10247.9 PVD38231.1 - 0.004 17.5 4.8 0.074 13.4 1.0 2.8 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 DUF2755 PF10954.8 PVD38231.1 - 0.092 12.7 0.9 0.31 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) RNA_pol_Rbc25 PF08292.12 PVD38233.1 - 8.6e-41 139.2 0.1 1.4e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PVD38233.1 - 6.3e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 PVD38233.1 - 0.00014 22.1 0.1 0.00025 21.3 0.1 1.6 1 1 0 1 1 1 1 S1 RNA binding domain PDDEXK_9 PF08011.11 PVD38233.1 - 0.082 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1712 PF08217.11 PVD38234.1 - 1.4e-66 225.3 3.0 5.6e-62 210.1 0.7 2.4 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) PH PF00169.29 PVD38234.1 - 5.1e-18 65.5 0.1 7.7e-13 48.9 0.0 2.9 2 0 0 2 2 2 2 PH domain ArfGap PF01412.18 PVD38234.1 - 6e-14 52.1 0.0 1.5e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_11 PF15413.6 PVD38234.1 - 0.00015 22.2 1.0 0.025 15.0 0.6 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PVD38234.1 - 0.0052 16.9 0.0 0.087 12.9 0.0 2.7 1 1 0 1 1 1 1 PH domain PH_2 PF08458.10 PVD38234.1 - 0.035 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region DUF4945 PF16303.5 PVD38234.1 - 0.099 12.6 0.1 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) PH_17 PF18012.1 PVD38234.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 PH domain Glyco_hydro_85 PF03644.13 PVD38235.1 - 5.3e-90 301.9 0.0 8.3e-90 301.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 CAF1 PF04857.20 PVD38240.1 - 1.1e-82 277.8 2.8 1.4e-82 277.5 2.8 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 PVD38240.1 - 4.6e-31 106.7 0.0 9.9e-31 105.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 PVD38240.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain DNA_pol_A_exo1 PF01612.20 PVD38240.1 - 0.017 14.9 0.2 0.33 10.6 0.0 2.6 2 1 0 2 2 2 0 3'-5' exonuclease RRM_1 PF00076.22 PVD38240.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 PVD38241.1 - 9.9e-09 34.9 8.0 2.2e-08 33.9 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD38241.1 - 1.5e-08 34.3 5.7 2.7e-08 33.5 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PVD38241.1 - 4.9e-08 32.9 3.2 1.9e-06 27.8 4.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD38241.1 - 6.3e-08 32.6 7.9 1.3e-07 31.7 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PVD38241.1 - 1.1e-06 28.4 8.7 1.1e-06 28.4 8.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD38241.1 - 1.4e-05 25.4 8.1 2.6e-05 24.5 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD38241.1 - 5.4e-05 23.1 7.4 5.4e-05 23.1 7.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain SAM_1 PF00536.30 PVD38241.1 - 8.1e-05 23.0 0.3 0.00015 22.1 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-RING_10 PF16685.5 PVD38241.1 - 8.6e-05 22.6 5.4 0.00017 21.7 5.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PVD38241.1 - 0.041 13.9 2.7 0.096 12.7 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAM_2 PF07647.17 PVD38241.1 - 0.049 13.7 0.3 0.092 12.9 0.3 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) U-box PF04564.15 PVD38241.1 - 0.058 13.6 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 U-box domain Prok-RING_4 PF14447.6 PVD38241.1 - 0.11 12.4 8.1 0.86 9.5 8.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PVD38241.1 - 0.39 10.5 7.2 0.26 11.1 3.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 PVD38241.1 - 0.48 10.1 4.6 1.1 9.0 4.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Neur_chan_LBD PF02931.23 PVD38242.1 - 1e-64 217.9 1.9 1.2e-64 217.7 1.9 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38242.1 - 3.1e-07 30.7 0.7 4.5e-07 30.2 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 PVD38243.1 - 1.5e-13 51.4 0.0 2.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MARVEL PF01284.23 PVD38243.1 - 0.021 14.9 0.2 5.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Membrane-associating domain DUF2721 PF11026.8 PVD38243.1 - 0.058 13.3 2.7 0.18 11.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Neur_chan_LBD PF02931.23 PVD38244.1 - 4e-07 29.7 0.1 5.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 PVD38246.1 - 2.1e-24 86.2 0.9 3.5e-24 85.5 0.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38246.1 - 4.1e-19 69.6 4.3 2.9e-18 66.8 4.3 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MIP-T3_C PF17749.1 PVD38246.1 - 0.14 12.1 0.8 0.2 11.6 0.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF2304 PF10066.9 PVD38246.1 - 0.25 11.6 4.6 0.6 10.4 4.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) SelP_N PF04592.14 PVD38247.1 - 0.13 11.6 15.9 0.14 11.6 15.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UreE_N PF02814.15 PVD38247.1 - 0.27 10.8 1.4 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Orbi_VP6 PF01516.16 PVD38248.1 - 0.028 13.9 3.9 0.032 13.8 3.9 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 Connexin PF00029.19 PVD38248.1 - 0.033 13.9 0.4 0.034 13.9 0.4 1.0 1 0 0 1 1 1 0 Connexin Casc1 PF12366.8 PVD38248.1 - 0.04 13.5 1.3 0.041 13.4 1.3 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 RasGAP PF00616.19 PVD38248.1 - 0.063 13.0 2.7 0.065 12.9 2.7 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase US6 PF17616.2 PVD38248.1 - 0.081 12.9 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Viral unique short region 6 YqfQ PF14181.6 PVD38248.1 - 0.72 10.0 6.9 0.98 9.6 6.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF3464 PF11947.8 PVD38248.1 - 0.93 9.2 3.5 1 9.1 3.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CDC45 PF02724.14 PVD38248.1 - 4.7 5.4 7.4 5.3 5.2 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 PVD38248.1 - 7.8 5.6 13.2 9.3 5.3 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Helicase_C_2 PF13307.6 PVD38249.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.0 1 0 0 1 1 1 0 Helicase C-terminal domain Neur_chan_memb PF02932.16 PVD38253.1 - 0.015 15.4 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Z1 PF10593.9 PVD38253.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Z1 domain TPR_19 PF14559.6 PVD38254.1 - 2.4e-21 76.0 13.3 6.6e-05 23.3 1.2 7.5 6 2 2 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD38254.1 - 5.6e-14 52.1 28.9 2.5e-07 30.8 0.5 5.8 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD38254.1 - 3.3e-12 46.8 1.3 8.3e-05 23.2 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PVD38254.1 - 6.2e-12 45.3 4.1 0.0096 16.7 0.0 7.1 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD38254.1 - 5.6e-09 35.4 35.7 0.044 13.9 0.1 9.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 PVD38254.1 - 1.1e-06 28.7 1.5 0.0069 16.5 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD38254.1 - 7.9e-06 25.5 6.3 0.37 10.9 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD38254.1 - 0.00039 20.4 11.7 0.82 10.0 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD38254.1 - 0.00064 20.2 17.8 0.14 12.9 0.0 7.5 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 PVD38254.1 - 0.0022 17.7 25.7 0.014 15.2 0.1 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat PPR PF01535.20 PVD38254.1 - 0.01 16.0 1.6 12 6.5 0.1 4.8 5 0 0 5 5 5 0 PPR repeat TPR_11 PF13414.6 PVD38254.1 - 0.04 13.6 0.2 0.88 9.3 0.0 3.1 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 PVD38254.1 - 0.048 14.3 0.0 63 4.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 PVD38254.1 - 0.077 12.4 2.8 0.25 10.7 0.6 2.9 2 1 0 2 2 2 0 Coatomer epsilon subunit FMN_red PF03358.15 PVD38254.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase TPR_12 PF13424.6 PVD38254.1 - 0.098 13.0 16.1 1 9.7 0.1 6.7 7 2 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD38254.1 - 1.1 9.4 11.6 1.3 9.2 0.3 4.8 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 PVD38254.1 - 4.3 7.9 12.3 9.1 6.9 0.1 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF4507 PF14964.6 PVD38255.1 - 6.7e-67 225.9 4.4 8.5e-67 225.6 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) LigT_PEase PF02834.16 PVD38255.1 - 4.3e-05 23.6 0.0 9.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 LigT like Phosphoesterase Acetyltransf_1 PF00583.25 PVD38256.1 - 0.062 13.5 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family UPF0542 PF15086.6 PVD38257.1 - 0.17 11.9 2.6 0.53 10.2 2.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 RNase_T PF00929.24 PVD38258.1 - 1.3e-20 74.6 0.0 2.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease zf-GRF PF06839.12 PVD38258.1 - 2.9e-11 43.3 7.9 1.2e-10 41.3 7.9 2.2 1 0 0 1 1 1 1 GRF zinc finger Polbeta PF18765.1 PVD38258.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Trypsin PF00089.26 PVD38259.1 - 1.9e-31 109.6 0.0 2.1e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 PVD38259.1 - 0.00017 21.9 0.1 0.0032 17.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 PVD38259.1 - 0.00023 22.1 0.0 0.00032 21.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 PVD38259.1 - 0.054 13.1 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 CDK2AP PF09806.9 PVD38261.1 - 4.2e-23 82.6 2.5 6.9e-23 81.9 2.5 1.6 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.13 PVD38261.1 - 1.3 9.7 10.9 1.8 9.2 10.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PVD38261.1 - 1.9 8.4 5.2 2.1 8.2 5.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ADH_zinc_N PF00107.26 PVD38262.1 - 1e-26 93.4 0.3 4.3e-26 91.4 0.1 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PVD38262.1 - 4.1e-15 55.6 14.0 2.4e-14 53.2 12.6 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 PVD38262.1 - 6.9e-11 42.0 0.6 6.7e-10 38.8 0.6 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PVD38262.1 - 2.1e-08 35.3 0.0 4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PVD38262.1 - 3e-05 23.4 0.8 5e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 PVD38262.1 - 0.0012 18.3 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PVD38262.1 - 0.0013 19.4 0.1 0.0038 17.9 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 PVD38262.1 - 0.043 13.9 0.2 0.077 13.1 0.2 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 PVD38262.1 - 0.069 12.7 0.3 2.1 7.9 0.2 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_C2 PF00648.21 PVD38263.1 - 1.2e-111 372.5 0.0 6.5e-105 350.4 0.0 3.2 2 1 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 PVD38263.1 - 9.6e-37 126.4 0.0 6.4e-35 120.5 0.0 2.9 3 0 0 3 3 3 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 PVD38263.1 - 3.7e-07 29.6 1.4 0.00062 19.5 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 PVD38263.1 - 3.4e-06 27.4 2.6 0.0065 16.9 0.0 2.8 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD38263.1 - 1.1e-05 24.7 0.4 0.023 14.2 0.1 3.9 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 PVD38263.1 - 1.5e-05 24.7 1.6 0.0091 15.8 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain pair Mito_fiss_reg PF05308.11 PVD38263.1 - 0.2 11.7 1.2 0.36 10.9 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PVD38263.1 - 0.49 10.4 4.4 1.4 9.0 4.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mucin PF01456.17 PVD38263.1 - 0.54 10.3 17.5 1.1 9.3 17.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 PVD38263.1 - 1.4 8.9 12.5 3 7.8 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CAP_N PF01213.19 PVD38263.1 - 2 7.9 3.6 3.7 6.9 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_C2 PF00648.21 PVD38264.1 - 8.8e-87 290.9 0.0 1.3e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD38264.1 - 1.2e-33 116.3 0.0 2.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III DUF5634 PF18681.1 PVD38265.1 - 0.18 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Ank_2 PF12796.7 PVD38266.1 - 1.7e-35 121.5 6.3 5.4e-12 46.1 0.0 4.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38266.1 - 2e-25 88.8 3.0 8.2e-07 29.5 0.0 5.6 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38266.1 - 4.6e-18 63.4 0.4 0.039 14.5 0.0 7.7 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PVD38266.1 - 8.6e-18 64.2 3.0 5.3e-05 23.4 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD38266.1 - 7.9e-14 51.4 8.8 0.011 16.1 0.0 6.6 5 3 2 7 7 7 5 Ankyrin repeat UDPGT PF00201.18 PVD38267.1 - 1.1e-117 393.9 4.2 4.7e-63 213.7 0.2 3.1 2 1 1 3 3 3 3 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD38267.1 - 4.7e-07 29.9 0.4 0.00036 20.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase family 28 C-terminal domain Glyco_transf_5 PF08323.11 PVD38267.1 - 0.0032 17.2 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 PVD38267.1 - 0.011 15.7 0.1 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 PVD38267.1 - 0.02 14.9 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like DUF627 PF04781.12 PVD38267.1 - 0.021 14.8 0.1 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ETC_C1_NDUFA5 PF04716.14 PVD38267.1 - 0.027 14.3 0.0 7.2 6.5 0.0 2.7 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF2368 PF10166.9 PVD38267.1 - 0.13 11.9 0.7 0.98 9.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Glyco_trans_4_4 PF13579.6 PVD38267.1 - 0.15 12.4 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Capsid_NCLDV PF04451.12 PVD38267.1 - 0.45 10.3 1.9 5.1 6.9 0.1 2.5 3 0 0 3 3 3 0 Large eukaryotic DNA virus major capsid protein UDPGT PF00201.18 PVD38268.1 - 4.1e-51 174.3 0.5 2.5e-32 112.4 0.0 2.1 1 1 1 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.6 PVD38268.1 - 0.0096 16.0 0.1 0.52 10.3 0.0 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 PVD38268.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4083 PF13314.6 PVD38268.1 - 0.072 13.0 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glyco_transf_4 PF13439.6 PVD38268.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 UDPGT PF00201.18 PVD38269.1 - 2.4e-73 247.6 0.0 4e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD38269.1 - 0.00098 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF4083 PF13314.6 PVD38269.1 - 0.018 15.0 1.1 0.035 14.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glyco_trans_4_2 PF13477.6 PVD38269.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 PVD38269.1 - 0.12 12.4 0.2 0.38 10.7 0.1 2.0 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Acetyltransf_3 PF13302.7 PVD38270.1 - 4.7e-27 95.3 0.0 9.5e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CAP PF00188.26 PVD38270.1 - 6.9e-23 81.8 1.2 1.5e-22 80.8 1.2 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Acetyltransf_1 PF00583.25 PVD38270.1 - 1.1e-06 28.8 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 PVD38270.1 - 1.3e-05 24.9 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PVD38270.1 - 4.2e-05 23.4 0.0 0.00011 22.1 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 PVD38270.1 - 8.6e-05 22.7 0.1 0.00014 22.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aa_trans PF01490.18 PVD38271.1 - 1.4e-25 89.9 27.9 2.1e-25 89.3 27.9 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Nucleopor_Nup85 PF07575.13 PVD38272.1 - 1.9e-154 515.4 14.3 2.3e-154 515.1 14.3 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin DNA_pol_B_palm PF14792.6 PVD38272.1 - 7.9e-36 122.7 0.0 4.8e-35 120.2 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 PVD38272.1 - 3.5e-18 65.2 0.0 1.9e-17 62.8 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 PVD38272.1 - 4.4e-13 49.2 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.6 PVD38272.1 - 3.3e-08 34.0 1.8 0.00026 21.5 0.0 3.0 2 1 1 3 3 3 2 Helix-hairpin-helix domain Cdd1 PF11731.8 PVD38272.1 - 0.0011 19.2 0.0 0.0063 16.7 0.0 2.4 1 1 1 2 2 2 1 Pathogenicity locus NTP_transf_2 PF01909.23 PVD38272.1 - 0.0012 19.1 0.1 0.0033 17.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4332 PF14229.6 PVD38272.1 - 0.017 15.3 0.2 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) HHH_3 PF12836.7 PVD38272.1 - 0.12 12.6 1.8 7.3 6.9 0.0 3.9 5 0 0 5 5 5 0 Helix-hairpin-helix motif HHH_8 PF14716.6 PVD38272.1 - 0.19 12.1 1.1 16 5.9 0.2 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain SIS PF01380.22 PVD38273.1 - 1.1e-54 183.8 0.1 1e-35 122.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 PVD38273.1 - 0.00035 20.6 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 SIS domain Aminotran_3 PF00202.21 PVD38274.1 - 7.8e-81 271.8 0.0 9.7e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CUB PF00431.20 PVD38276.1 - 2.6e-62 208.0 0.1 1.8e-21 76.5 0.0 4.2 5 0 0 5 5 5 3 CUB domain Sushi PF00084.20 PVD38276.1 - 6.2e-54 180.4 56.1 1.1e-09 38.7 1.2 10.8 9 1 1 10 10 10 8 Sushi repeat (SCR repeat) EGF_CA PF07645.15 PVD38276.1 - 3.1e-10 40.1 23.6 3.4e-07 30.3 7.4 6.3 7 0 0 7 7 7 2 Calcium-binding EGF domain Ldl_recept_a PF00057.18 PVD38276.1 - 8.2e-09 35.5 13.1 8.2e-09 35.5 13.1 3.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 PVD38276.1 - 4.7e-07 30.0 9.9 4.7e-07 30.0 9.9 5.4 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site Lectin_C PF00059.21 PVD38276.1 - 1.1e-05 26.1 0.8 5.7e-05 23.8 0.8 2.3 1 0 0 1 1 1 1 Lectin C-type domain hEGF PF12661.7 PVD38276.1 - 0.012 16.2 5.4 0.012 16.2 5.4 5.5 4 0 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.7 PVD38276.1 - 0.64 10.0 58.8 0.014 15.3 2.9 9.8 10 0 0 10 10 10 0 Complement Clr-like EGF-like EGF PF00008.27 PVD38276.1 - 4.7 7.6 44.9 0.013 15.8 6.2 5.0 5 0 0 5 5 5 0 EGF-like domain EGF PF00008.27 PVD38277.1 - 1.5e-84 277.7 237.3 1.9e-08 34.5 5.5 19.4 18 0 0 18 18 18 15 EGF-like domain Ephrin_rec_like PF07699.13 PVD38277.1 - 1.2e-63 210.7 110.2 1.3e-10 40.8 2.8 10.5 8 1 1 9 9 8 8 Putative ephrin-receptor like hEGF PF12661.7 PVD38277.1 - 1.2e-48 162.2 204.5 3.4e-07 30.7 5.2 21.1 19 0 0 19 19 17 14 Human growth factor-like EGF HYR PF02494.16 PVD38277.1 - 4.1e-23 81.5 3.0 7.8e-13 48.6 0.4 3.8 3 0 0 3 3 3 3 HYR domain Laminin_G_3 PF13385.6 PVD38277.1 - 3.7e-12 46.6 0.0 1e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 PVD38277.1 - 8.5e-09 35.5 16.1 8.5e-09 35.5 16.1 18.8 15 4 4 19 19 17 9 EGF domain cEGF PF12662.7 PVD38277.1 - 1.4e-05 24.9 2.8 1.4e-05 24.9 2.8 23.7 23 4 1 24 24 22 4 Complement Clr-like EGF-like EGF_CA PF07645.15 PVD38277.1 - 0.00014 22.0 30.2 0.00017 21.7 12.8 23.9 13 5 12 25 25 22 12 Calcium-binding EGF domain Laminin_G_2 PF02210.24 PVD38277.1 - 0.0018 18.8 0.1 0.0035 17.9 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain EGF_2 PF07974.13 PVD38277.1 - 0.0027 18.1 7.9 0.0027 18.1 7.9 19.2 17 1 1 18 18 17 8 EGF-like domain Laminin_G_1 PF00054.23 PVD38277.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Laminin_EGF PF00053.24 PVD38279.1 - 2.5 8.3 143.2 1.4e+02 2.7 19.2 8.4 1 1 6 7 7 7 0 Laminin EGF domain SNF PF00209.18 PVD38280.1 - 8.1e-164 546.2 40.2 1.1e-64 219.0 4.6 4.1 1 1 3 4 4 4 4 Sodium:neurotransmitter symporter family SNARE PF05739.19 PVD38281.1 - 0.00013 21.9 0.1 0.00013 21.9 0.1 2.0 2 0 0 2 2 2 1 SNARE domain MscS_porin PF12795.7 PVD38281.1 - 2.9 7.4 11.0 0.53 9.8 0.9 2.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain YkyA PF10368.9 PVD38281.1 - 4.6 6.9 7.6 0.27 10.9 0.6 2.4 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein TPR_2 PF07719.17 PVD38282.1 - 2.9e-07 30.1 6.2 0.028 14.5 1.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD38282.1 - 1.8e-06 27.5 8.8 0.0027 17.5 1.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD38282.1 - 7.1e-06 26.2 7.5 2.7e-05 24.3 7.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PVD38282.1 - 7.9e-05 23.2 0.5 0.008 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD38282.1 - 0.0019 17.9 3.6 0.71 9.6 0.2 3.0 3 0 0 3 3 3 2 TPR repeat DUF3856 PF12968.7 PVD38282.1 - 0.0021 18.1 1.2 0.017 15.2 0.4 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 PVD38282.1 - 0.02 15.0 6.0 0.068 13.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD38282.1 - 0.025 15.1 5.7 0.052 14.1 1.8 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PVD38282.1 - 0.035 14.2 1.8 0.83 9.8 0.5 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD38282.1 - 0.042 13.9 1.2 0.16 12.0 1.2 2.1 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_12 PF13424.6 PVD38282.1 - 0.071 13.4 2.6 0.36 11.2 1.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 PVD38282.1 - 0.088 13.1 9.5 0.29 11.5 9.5 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding YmgB PF10798.8 PVD38282.1 - 0.088 12.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR SHNi-TPR PF10516.9 PVD38282.1 - 0.25 10.8 2.5 0.44 10.0 0.5 2.3 2 0 0 2 2 2 0 SHNi-TPR AAA_12 PF13087.6 PVD38283.1 - 4.5e-72 241.9 0.0 1.2e-35 123.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PVD38283.1 - 4.2e-69 233.2 6.9 1.6e-39 136.2 1.7 4.1 2 2 1 3 3 3 3 AAA domain RNB PF00773.19 PVD38283.1 - 2.5e-45 155.2 0.1 6.5e-45 153.9 0.1 1.8 1 0 0 1 1 1 1 RNB domain AAA_30 PF13604.6 PVD38283.1 - 1.2e-19 70.7 0.0 6e-08 32.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PVD38283.1 - 9.4e-15 55.2 1.2 2.7e-07 31.0 0.3 3.5 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PVD38283.1 - 4.8e-10 39.6 2.9 0.23 11.2 0.1 5.3 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 PVD38283.1 - 1e-05 25.1 1.2 0.1 12.0 0.1 3.6 3 1 0 3 3 3 2 PhoH-like protein AAA_22 PF13401.6 PVD38283.1 - 6.7e-05 23.2 0.0 0.48 10.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 PVD38283.1 - 8e-05 22.4 1.2 0.14 12.1 0.3 4.1 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 PVD38283.1 - 8.1e-05 22.3 1.9 0.58 9.6 0.0 3.6 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 PVD38283.1 - 0.00013 22.0 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 PVD38283.1 - 0.00064 19.6 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 Helicase PIF1 PF05970.14 PVD38283.1 - 0.0011 18.3 0.0 4 6.5 0.0 3.9 4 0 0 4 4 4 1 PIF1-like helicase AAA_5 PF07728.14 PVD38283.1 - 0.0013 18.8 0.0 0.27 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PVD38283.1 - 0.0022 17.5 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PVD38283.1 - 0.017 14.5 0.0 7 6.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 PVD38283.1 - 0.021 14.0 0.0 9.3 5.3 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 PVD38283.1 - 0.022 14.4 0.0 0.43 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PVD38283.1 - 0.052 13.9 0.0 3.2 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain OB_Dis3 PF17849.1 PVD38283.1 - 0.064 13.3 0.0 0.24 11.5 0.0 2.0 1 1 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) RNA_helicase PF00910.22 PVD38283.1 - 0.1 13.0 0.0 8 6.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 PVD38283.1 - 0.12 12.8 0.0 28 5.1 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 PVD38283.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.6 PVD38283.1 - 0.16 11.7 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PVD38283.1 - 0.18 11.0 0.1 22 4.1 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AMP-binding PF00501.28 PVD38284.1 - 3.9e-80 269.5 0.0 5.3e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD38284.1 - 0.0026 18.7 0.2 0.0067 17.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CCDC24 PF15669.5 PVD38286.1 - 0.011 15.6 0.7 0.61 9.9 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family EPF PF17181.4 PVD38286.1 - 3.1 7.9 7.5 0.25 11.4 1.5 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins CSTF_C PF14304.6 PVD38287.1 - 0.1 12.2 0.3 0.65 9.6 0.1 2.2 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Exo70 PF03081.15 PVD38288.1 - 9e-67 225.7 4.0 9e-67 225.7 4.0 2.5 3 1 0 3 3 3 1 Exo70 exocyst complex subunit COG5 PF10392.9 PVD38288.1 - 0.014 15.6 1.2 0.051 13.8 1.2 2.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 COG6 PF06419.11 PVD38288.1 - 0.015 13.6 13.1 0.076 11.2 0.4 3.2 3 0 0 3 3 3 0 Conserved oligomeric complex COG6 Sec34 PF04136.15 PVD38288.1 - 0.022 14.7 0.4 0.022 14.7 0.4 2.5 2 0 0 2 2 2 0 Sec34-like family RIH_assoc PF08454.11 PVD38288.1 - 0.22 11.4 1.8 0.97 9.3 0.0 3.0 3 1 1 4 4 4 0 RyR and IP3R Homology associated Snapin_Pallidin PF14712.6 PVD38288.1 - 0.9 10.0 4.1 3.5 8.1 0.1 3.3 2 1 0 2 2 2 0 Snapin/Pallidin TMF_TATA_bd PF12325.8 PVD38288.1 - 1.3 9.2 8.0 4.5 7.5 0.5 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Sec3_C PF09763.9 PVD38288.1 - 2.1 6.6 13.0 0.029 12.8 0.7 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec3 Tetraspanin PF00335.20 PVD38290.1 - 2.1e-43 148.7 9.3 2.4e-43 148.5 9.3 1.0 1 0 0 1 1 1 1 Tetraspanin family MFS_1 PF07690.16 PVD38290.1 - 0.051 12.5 9.8 0.14 11.0 4.7 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily Otopetrin PF03189.13 PVD38290.1 - 0.69 8.7 5.8 1.1 8.0 5.8 1.3 1 0 0 1 1 1 0 Otopetrin Transmemb_17 PF09799.9 PVD38290.1 - 1.9 9.1 13.8 0.17 12.5 8.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein Tmemb_55A PF09788.9 PVD38290.1 - 2 7.5 5.8 0.26 10.3 1.0 1.8 1 1 2 3 3 3 0 Transmembrane protein 55A DUF2362 PF10154.9 PVD38291.1 - 6.1e-175 583.0 9.7 7.6e-175 582.6 9.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Dehydrin PF00257.19 PVD38291.1 - 0.24 11.9 3.9 0.42 11.1 3.9 1.4 1 0 0 1 1 1 0 Dehydrin FAM150 PF15129.6 PVD38291.1 - 0.86 9.8 4.1 1.2 9.4 0.3 2.6 2 1 0 2 2 2 0 FAM150 family Thioredoxin PF00085.20 PVD38292.1 - 9.5e-65 215.1 4.7 4.4e-33 113.4 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 PVD38292.1 - 2.2e-46 158.1 12.4 1.8e-40 138.8 3.3 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 PVD38292.1 - 2.1e-12 47.0 1.5 1.1e-05 25.0 0.0 3.2 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 PVD38292.1 - 2.4e-11 43.7 0.4 0.0012 19.0 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 PVD38292.1 - 1.9e-10 40.9 1.9 0.0012 19.1 0.0 4.4 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PVD38292.1 - 4.2e-10 40.0 4.8 0.00042 20.7 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 PVD38292.1 - 1.9e-08 34.3 5.2 0.011 15.7 0.1 3.8 3 1 1 4 4 4 2 AhpC/TSA family ERp29_N PF07912.13 PVD38292.1 - 4.7e-07 30.0 4.5 1.6 8.9 0.0 4.8 4 2 0 4 4 4 3 ERp29, N-terminal domain Redoxin PF08534.10 PVD38292.1 - 2.1e-06 27.5 4.1 0.0057 16.4 0.1 3.3 2 1 0 3 3 3 2 Redoxin MPP6 PF10175.9 PVD38292.1 - 0.00094 19.7 0.9 0.0024 18.4 0.9 1.7 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Glutaredoxin PF00462.24 PVD38292.1 - 0.0037 17.5 1.8 1.7 9.0 0.0 3.3 2 1 0 2 2 2 1 Glutaredoxin HyaE PF07449.11 PVD38292.1 - 0.0055 16.7 0.1 7.6 6.6 0.0 3.1 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 PVD38292.1 - 0.0074 16.1 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 1 F plasmid transfer operon protein DUF4170 PF13773.6 PVD38292.1 - 0.2 11.8 0.7 0.73 10.0 0.2 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4170) NOA36 PF06524.12 PVD38292.1 - 1.2 8.4 4.5 2.1 7.6 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 PVD38292.1 - 3.9 7.9 11.2 12 6.4 11.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Calx-beta PF03160.14 PVD38293.1 - 1.1e-34 118.6 0.2 8.6e-17 61.1 0.0 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 PVD38293.1 - 7.6e-22 77.9 18.9 2.4e-21 76.3 12.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 PVD38293.1 - 0.00015 22.2 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DUF5362 PF17319.2 PVD38293.1 - 3.5 7.6 6.3 0.33 10.8 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Tmem26 PF09772.9 PVD38294.1 - 2.6e-29 102.5 0.3 4e-29 101.9 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 CUB PF00431.20 PVD38295.1 - 1.5e-31 109.0 0.0 6e-16 58.8 0.0 3.6 3 0 0 3 3 3 3 CUB domain Ephrin_rec_like PF07699.13 PVD38295.1 - 2.2e-22 78.6 31.2 1.8e-11 43.6 8.4 3.5 2 1 1 3 3 3 3 Putative ephrin-receptor like CUB_2 PF02408.20 PVD38295.1 - 0.0006 19.6 0.0 0.032 14.0 0.0 2.8 2 1 0 2 2 2 1 CUB-like domain TNFR_c6 PF00020.18 PVD38295.1 - 0.001 19.4 23.0 0.08 13.4 0.9 5.5 2 2 2 4 4 4 4 TNFR/NGFR cysteine-rich region SEA PF01390.20 PVD38295.1 - 0.0016 18.5 0.2 0.0038 17.3 0.2 1.6 1 0 0 1 1 1 1 SEA domain Sushi PF00084.20 PVD38295.1 - 0.011 16.3 0.1 0.011 16.3 0.1 3.8 2 1 1 3 3 3 0 Sushi repeat (SCR repeat) Cnn_1N PF07989.11 PVD38296.1 - 0.0045 17.1 0.8 0.0045 17.1 0.8 2.5 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 DUF4763 PF15960.5 PVD38296.1 - 0.032 13.6 1.2 0.41 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) HALZ PF02183.18 PVD38296.1 - 0.074 13.3 4.4 0.56 10.5 0.2 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 PVD38296.1 - 0.13 12.4 4.4 0.16 12.2 0.9 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 PVD38296.1 - 0.4 10.5 3.9 4.4 7.1 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator CLZ PF16526.5 PVD38296.1 - 0.49 10.8 5.6 2 8.8 0.4 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 PVD38296.1 - 0.57 10.2 5.1 3.1 7.8 0.5 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 PVD38296.1 - 0.71 10.0 9.9 0.36 10.9 2.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIVA PF05103.13 PVD38296.1 - 1.1 9.4 7.6 0.3 11.2 2.9 2.3 2 1 0 2 2 2 0 DivIVA protein CENP-Q PF13094.6 PVD38296.1 - 1.1 9.4 10.4 14 5.8 10.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.11 PVD38296.1 - 1.2 9.5 4.6 2.2 8.6 1.0 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 WD40 PF00400.32 PVD38299.1 - 1.2e-08 35.5 11.5 0.002 18.9 0.3 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38299.1 - 0.00039 20.7 0.5 0.026 14.8 0.0 3.3 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD38299.1 - 0.0042 17.0 0.1 0.019 14.8 0.0 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A UDPGT PF00201.18 PVD38300.1 - 9.9e-59 199.4 0.0 1.3e-58 199.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_4 PF13579.6 PVD38300.1 - 0.014 15.9 0.4 0.014 15.9 0.4 2.7 2 2 1 3 3 3 0 Glycosyl transferase 4-like domain Glyco_tran_28_C PF04101.16 PVD38300.1 - 0.04 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 PVD38300.1 - 0.33 10.9 2.9 0.74 9.8 0.5 2.7 2 1 1 3 3 3 0 Glycosyltransferase Family 4 UDPGT PF00201.18 PVD38301.1 - 6.8e-53 180.2 0.0 8.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD38301.1 - 0.03 14.3 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain CN_hydrolase PF00795.22 PVD38302.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Pkinase PF00069.25 PVD38303.1 - 3e-40 138.2 0.0 4.3e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38303.1 - 2.2e-36 125.5 0.0 1.3e-35 123.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PVD38304.1 - 3.4e-43 146.1 14.1 1.4e-12 48.0 0.4 6.5 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38304.1 - 4.7e-35 119.5 10.7 9.4e-06 26.1 0.0 8.3 6 2 1 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD38304.1 - 7.9e-30 102.5 7.4 3.5e-06 27.2 0.0 8.3 6 2 3 9 9 8 7 Ankyrin repeats (many copies) LRR_8 PF13855.6 PVD38304.1 - 1.8e-26 91.6 21.7 2e-09 37.0 1.6 5.8 5 0 0 5 5 5 5 Leucine rich repeat Ank_3 PF13606.6 PVD38304.1 - 3.5e-23 79.1 17.4 0.034 14.7 0.0 10.4 11 0 0 11 11 10 6 Ankyrin repeat Ank PF00023.30 PVD38304.1 - 7.9e-22 76.7 20.6 0.00014 22.1 0.2 9.5 9 1 0 9 9 9 5 Ankyrin repeat LRR_4 PF12799.7 PVD38304.1 - 1.6e-21 76.0 26.5 2.6e-05 24.5 0.6 9.0 8 0 0 8 8 8 5 Leucine Rich repeats (2 copies) Roc PF08477.13 PVD38304.1 - 8.1e-18 64.8 0.1 4.2e-14 52.8 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PVD38304.1 - 3.4e-06 26.8 0.0 8.1e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Ras family LRR_1 PF00560.33 PVD38304.1 - 0.0013 19.0 27.3 8.7 7.3 0.1 10.7 12 0 0 12 12 10 2 Leucine Rich Repeat Arf PF00025.21 PVD38304.1 - 0.0019 17.7 0.2 0.43 10.0 0.2 2.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF5315 PF17242.2 PVD38304.1 - 0.16 11.8 1.0 12 5.8 0.0 3.1 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) LRR_9 PF14580.6 PVD38304.1 - 0.23 11.0 2.7 0.99 8.9 0.1 3.0 3 0 0 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 PVD38304.1 - 3.8 7.8 32.0 4.2 7.7 0.0 9.7 11 0 0 11 11 10 0 Leucine Rich repeat NTP_transferase PF00483.23 PVD38305.1 - 3.4e-17 62.9 0.0 4.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase UQ_con PF00179.26 PVD38305.1 - 3.4e-16 59.2 0.0 7.4e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hexapep PF00132.24 PVD38305.1 - 5.1e-10 38.7 6.6 2.2e-07 30.3 0.3 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) ZipA_C PF04354.13 PVD38305.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain DUF2746 PF10874.8 PVD38305.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) SH2 PF00017.24 PVD38306.1 - 9.2e-12 44.9 1.8 5e-11 42.5 0.1 3.1 4 0 0 4 4 4 1 SH2 domain SOCS_box PF07525.16 PVD38306.1 - 7.7e-08 32.6 0.8 1.7e-07 31.5 0.8 1.6 1 0 0 1 1 1 1 SOCS box SH2_2 PF14633.6 PVD38306.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 SH2 domain Nop PF01798.18 PVD38307.1 - 3.8e-41 141.0 0.5 1.5e-22 80.2 0.1 2.6 1 1 1 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PVD38307.1 - 7.5e-21 74.3 2.3 3.4e-20 72.2 2.3 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RsfS PF02410.15 PVD38308.1 - 2.9e-25 88.6 0.4 5.2e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CD34_antigen PF06365.12 PVD38310.1 - 0.14 11.7 0.3 0.17 11.5 0.3 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Gemini_mov PF01708.16 PVD38310.1 - 0.22 11.3 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein RCR PF12273.8 PVD38311.1 - 1.3e-05 25.9 0.6 7.8e-05 23.3 0.4 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF5518 PF17647.1 PVD38311.1 - 0.0003 20.9 4.7 0.18 12.0 0.4 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5518) Rax2 PF12768.7 PVD38311.1 - 0.011 15.2 0.2 0.6 9.5 0.3 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Mid2 PF04478.12 PVD38311.1 - 0.013 15.3 3.9 0.59 10.0 0.4 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Herpes_UL49_5 PF05702.11 PVD38311.1 - 0.032 14.3 0.9 0.054 13.6 0.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Podoplanin PF05808.11 PVD38311.1 - 0.045 13.9 0.7 8.6 6.4 0.5 2.2 2 0 0 2 2 2 0 Podoplanin EphA2_TM PF14575.6 PVD38311.1 - 0.046 14.6 0.6 17 6.4 0.1 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Plant_vir_prot PF01307.17 PVD38311.1 - 0.13 12.5 1.7 0.23 11.7 0.3 2.0 2 0 0 2 2 2 0 Plant viral movement protein PTP_tm PF18861.1 PVD38311.1 - 0.49 10.4 6.7 0.15 12.0 0.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2937 PF11157.8 PVD38311.1 - 4.4 7.0 4.6 8.3 6.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Glyco_hydro_18 PF00704.28 PVD38314.1 - 2.6e-31 109.5 0.0 7.8e-26 91.5 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 7tm_1 PF00001.21 PVD38315.1 - 2e-41 142.1 11.9 3.6e-40 137.9 11.9 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 PVD38315.1 - 5e-06 26.1 7.4 5e-06 26.1 7.4 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 PVD38315.1 - 0.0004 20.1 4.5 0.0004 20.1 4.5 2.8 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 PVD38315.1 - 0.0014 18.4 7.3 0.0014 18.4 7.3 2.6 2 1 1 3 3 3 1 Srg family chemoreceptor SieB PF14163.6 PVD38315.1 - 0.0065 16.0 0.2 0.0065 16.0 0.2 3.2 3 0 0 3 3 3 1 Super-infection exclusion protein B HemY_N PF07219.13 PVD38315.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.2 4 0 0 4 4 4 0 HemY protein N-terminus EphA2_TM PF14575.6 PVD38315.1 - 1 10.3 0.1 1 10.3 0.1 3.2 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain GPS PF01825.21 PVD38316.1 - 2.5e-13 50.3 3.6 7.1e-13 48.9 3.6 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 PVD38316.1 - 8.4e-05 22.0 10.6 0.0011 18.3 0.4 3.2 1 1 2 3 3 3 3 7 transmembrane receptor (Secretin family) Innexin PF00876.18 PVD38318.1 - 3.1e-71 240.5 10.9 8.4e-56 189.8 4.3 2.1 1 1 1 2 2 2 2 Innexin Phage_int_SAM_5 PF13102.6 PVD38318.1 - 0.094 13.1 0.3 0.35 11.2 0.3 2.0 1 0 0 1 1 1 0 Phage integrase SAM-like domain Lustrin_cystein PF14625.6 PVD38319.1 - 0.066 13.6 0.2 0.066 13.6 0.2 1.8 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain BRO1 PF03097.18 PVD38324.1 - 4.2e-123 411.0 0.3 4.2e-123 411.0 0.3 1.8 2 0 0 2 2 2 1 BRO1-like domain Y_phosphatase PF00102.27 PVD38324.1 - 6.3e-56 189.6 0.0 1.4e-55 188.4 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ALIX_LYPXL_bnd PF13949.6 PVD38324.1 - 2.1e-48 165.1 18.4 5.7e-48 163.7 18.4 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DSPc PF00782.20 PVD38324.1 - 2.5e-05 24.1 2.5 0.00031 20.6 0.0 2.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Csm2_III-A PF03750.13 PVD38324.1 - 3.8 8.4 8.2 1.3 9.9 3.2 2.6 1 1 1 2 2 2 0 Csm2 Type III-A zf-C4 PF00105.18 PVD38325.1 - 3.1e-28 98.0 13.9 5.6e-28 97.2 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD38325.1 - 4.5e-07 29.6 0.1 2.7e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2737 PF10930.8 PVD38325.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) GRASP55_65 PF04495.14 PVD38326.1 - 3.8e-76 254.0 0.0 5.1e-56 188.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 PVD38326.1 - 1.1e-09 38.5 0.0 6.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PVD38326.1 - 4.2e-06 26.5 0.0 0.13 12.1 0.0 2.8 2 2 0 2 2 2 2 PDZ domain PDZ PF00595.24 PVD38326.1 - 0.053 13.9 0.0 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Ion_trans PF00520.31 PVD38327.1 - 0.00079 18.7 3.4 0.00079 18.7 3.4 1.7 2 1 0 2 2 2 1 Ion transport protein RSS_P20 PF11757.8 PVD38327.1 - 0.12 12.8 1.3 7.9 7.0 1.3 2.3 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Globin PF00042.22 PVD38328.1 - 1.5e-16 60.9 0.3 9e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 Globin Str_synth PF03088.16 PVD38328.1 - 1.4e-10 41.2 0.0 7.1e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 PVD38328.1 - 2.3e-09 37.2 0.0 6.3e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region TetR_C_10 PF16295.5 PVD38328.1 - 0.025 14.9 0.4 0.26 11.6 0.1 2.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PD40 PF07676.12 PVD38328.1 - 0.06 13.3 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DcrB PF08786.11 PVD38328.1 - 0.093 12.8 0.9 1.9 8.6 0.1 2.8 2 0 0 2 2 2 0 DcrB Neur_chan_LBD PF02931.23 PVD38329.1 - 1.1e-60 204.8 2.3 1.4e-60 204.4 2.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38329.1 - 3.6e-28 99.2 0.0 4.7e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4795 PF16043.5 PVD38329.1 - 0.016 14.8 0.2 0.028 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) RNase_H2_suC PF08615.11 PVD38329.1 - 0.92 9.7 2.1 0.6 10.3 0.2 1.6 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Neur_chan_LBD PF02931.23 PVD38330.1 - 6.2e-61 205.6 1.5 9e-61 205.1 1.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38330.1 - 1.6e-30 106.9 0.6 2.1e-30 106.5 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SPC25 PF06703.11 PVD38330.1 - 0.032 14.0 0.1 0.032 14.0 0.1 1.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Neur_chan_LBD PF02931.23 PVD38331.1 - 2.8e-65 219.8 2.9 3.6e-65 219.4 2.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38331.1 - 4.1e-32 112.1 0.0 6.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF677 PF05055.12 PVD38331.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF1706 PF08020.11 PVD38331.1 - 0.11 12.4 0.4 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Nop PF01798.18 PVD38332.1 - 9.6e-81 270.6 1.4 1.1e-80 270.5 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 PVD38332.1 - 2.5e-46 157.5 2.6 2.5e-46 157.5 2.6 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Guanylate_cyc PF00211.20 PVD38333.1 - 1.5e-51 174.6 0.1 2.7e-51 173.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 PVD38333.1 - 1.9e-41 142.3 0.0 2.6e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD38333.1 - 2.6e-16 59.7 0.0 2.6e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD38333.1 - 2.2e-13 50.2 0.0 3.6e-10 39.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 PVD38333.1 - 7.9e-06 25.5 0.3 1.3e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 PVD38333.1 - 4.4e-05 23.3 0.1 0.012 15.3 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Aminotran_3 PF00202.21 PVD38334.1 - 1.2e-133 445.7 0.5 2.4e-49 168.1 0.0 4.0 3 1 1 4 4 4 4 Aminotransferase class-III Aminotran_1_2 PF00155.21 PVD38334.1 - 0.018 14.2 0.1 0.069 12.3 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Telomere_Sde2_2 PF13297.6 PVD38334.1 - 0.085 12.5 0.0 27 4.5 0.0 3.1 3 0 0 3 3 3 0 Telomere stability C-terminal adh_short PF00106.25 PVD38335.1 - 1.6e-46 158.2 0.1 1.9e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38335.1 - 5.8e-38 130.7 0.0 7.3e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD38335.1 - 2.1e-12 47.4 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD38335.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 PVD38335.1 - 0.0025 18.4 0.1 0.0047 17.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 PVD38335.1 - 0.0068 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 PVD38335.1 - 0.0076 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 PVD38335.1 - 0.0093 15.5 0.0 0.26 10.8 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 PVD38335.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Oxidored_nitro PF00148.19 PVD38335.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.6 PVD38335.1 - 0.035 14.0 0.1 0.038 13.9 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 PVD38335.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 PVD38335.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GARS_N PF02844.15 PVD38335.1 - 0.046 14.5 0.0 4.4 8.1 0.0 2.7 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain HEM4 PF02602.15 PVD38335.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD adh_short PF00106.25 PVD38336.1 - 9.8e-46 155.7 0.2 1.2e-45 155.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38336.1 - 1.8e-36 125.9 0.0 2.2e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD38336.1 - 2.3e-11 43.9 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PVD38336.1 - 0.00046 19.7 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HEM4 PF02602.15 PVD38336.1 - 0.0048 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD GDP_Man_Dehyd PF16363.5 PVD38336.1 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 PVD38336.1 - 0.0081 16.7 0.1 0.015 15.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PVD38336.1 - 0.024 14.9 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 PVD38336.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 PVD38336.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding LDcluster4 PF18306.1 PVD38336.1 - 0.042 13.4 0.6 0.075 12.6 0.6 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Oxidored_nitro PF00148.19 PVD38336.1 - 0.058 12.1 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase RmlD_sub_bind PF04321.17 PVD38336.1 - 0.082 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 PVD38336.1 - 0.093 12.3 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Helicase_RecD PF05127.14 PVD38336.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase G-gamma PF00631.22 PVD38337.1 - 3.2e-13 49.5 0.1 3.6e-13 49.3 0.1 1.0 1 0 0 1 1 1 1 GGL domain NUDE_C PF04880.13 PVD38337.1 - 0.046 14.2 0.3 0.046 14.2 0.3 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SIR2 PF02146.17 PVD38338.1 - 1.2e-64 217.5 0.0 2.6e-64 216.4 0.0 1.6 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 PVD38338.1 - 0.0033 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 PVD38338.1 - 0.0057 16.4 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF3677 PF12432.8 PVD38339.1 - 6.9e-29 100.0 1.1 6.9e-29 100.0 1.1 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3677) Cnd1 PF12717.7 PVD38339.1 - 0.00027 21.0 4.3 0.0025 17.9 0.1 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PVD38339.1 - 0.36 11.2 2.3 23 5.6 0.1 4.2 3 0 0 3 3 3 0 HEAT repeat DIL PF01843.19 PVD38340.1 - 5e-12 46.0 0.1 1.1e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 DIL domain RA PF00788.23 PVD38340.1 - 2.3e-09 37.7 0.0 4.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain 2OG-FeII_Oxy_3 PF13640.6 PVD38340.1 - 2.4e-08 34.8 0.1 5.3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FHA PF00498.26 PVD38340.1 - 0.032 14.6 0.4 0.065 13.6 0.4 1.5 1 0 0 1 1 1 0 FHA domain S4 PF01479.25 PVD38340.1 - 0.19 11.5 0.8 20 5.0 0.1 2.5 2 0 0 2 2 2 0 S4 domain VWA_3 PF13768.6 PVD38341.1 - 1.7e-43 148.3 0.1 6.6e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 PVD38341.1 - 1e-17 64.9 0.0 2.3e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD38341.1 - 3.2e-13 50.3 0.0 1.4e-05 25.7 0.0 3.7 3 0 0 3 3 3 2 von Willebrand factor type A domain ATP11 PF06644.11 PVD38341.1 - 0.059 13.2 0.1 0.059 13.2 0.1 2.8 3 0 0 3 3 3 0 ATP11 protein VWA_CoxE PF05762.14 PVD38341.1 - 0.11 11.9 0.7 0.56 9.6 0.0 2.5 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein CobT PF06213.12 PVD38341.1 - 2.9 7.2 16.3 5.9 6.2 16.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rhabdo_ncap PF00945.18 PVD38341.1 - 4.6 6.0 5.8 8.3 5.2 5.8 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein HEAT PF02985.22 PVD38342.1 - 3.5e-14 51.7 6.0 1.6 9.2 0.0 10.6 12 0 0 12 12 12 3 HEAT repeat Cnd1 PF12717.7 PVD38342.1 - 1.1e-10 41.7 8.6 2.8e-05 24.2 0.0 5.8 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PVD38342.1 - 8.9e-10 39.0 3.1 0.026 15.1 0.0 6.5 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 PVD38342.1 - 1.8e-09 37.9 7.3 0.0011 19.5 0.1 7.8 8 1 2 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.6 PVD38342.1 - 1.5e-08 34.9 0.4 0.0015 18.9 0.0 5.7 7 1 0 7 7 7 2 HEAT repeats CLASP_N PF12348.8 PVD38342.1 - 2.5e-07 30.5 5.8 7.8e-05 22.3 0.1 4.1 5 0 0 5 5 5 2 CLASP N terminal Dopey_N PF04118.14 PVD38342.1 - 0.031 13.4 2.1 2.8 7.0 0.1 3.4 2 1 0 2 2 2 0 Dopey, N-terminal MMS19_N PF14500.6 PVD38342.1 - 0.082 12.5 6.7 4.7 6.7 0.3 4.3 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Telomere_reg-2 PF10193.9 PVD38342.1 - 0.12 12.8 0.6 1.1 9.8 0.1 2.9 2 0 0 2 2 2 0 Telomere length regulation protein DUF4777 PF16007.5 PVD38342.1 - 0.18 12.1 1.3 75 3.7 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4777) U3snoRNP10 PF12397.8 PVD38342.1 - 2.2 8.6 6.1 27 5.1 0.1 3.8 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 adh_short PF00106.25 PVD38343.1 - 6.6e-40 136.7 0.1 8.5e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD38343.1 - 3.7e-25 88.9 0.1 5.2e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD38343.1 - 0.00028 20.9 0.1 0.00041 20.3 0.1 1.2 1 0 0 1 1 1 1 KR domain HMG_box PF00505.19 PVD38345.1 - 3.3e-14 53.1 0.1 4.9e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 PVD38345.1 - 1.9e-12 48.1 1.2 4.8e-12 46.8 1.2 1.7 1 1 0 1 1 1 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 PVD38345.1 - 0.0065 17.0 0.1 0.0096 16.5 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 PVD38346.1 - 6.1e-05 23.4 0.2 8.7e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box TFIIA PF03153.13 PVD38347.1 - 0.0026 17.9 13.7 0.003 17.6 13.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neuregulin PF02158.15 PVD38347.1 - 0.0048 16.3 12.0 0.0061 16.0 12.0 1.1 1 0 0 1 1 1 1 Neuregulin intracellular region FAM199X PF15814.5 PVD38347.1 - 0.075 12.1 0.8 0.14 11.2 0.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X CAP_N PF01213.19 PVD38347.1 - 0.69 9.3 8.2 1.2 8.5 8.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM174 PF15029.6 PVD38347.1 - 1.3 8.7 6.4 2.9 7.5 6.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 174 Spt20 PF12090.8 PVD38347.1 - 2.1 7.9 20.2 3 7.4 20.2 1.1 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 PVD38347.1 - 3.9 5.6 13.7 4.8 5.3 13.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Auxin_resp PF06507.13 PVD38348.1 - 0.074 13.3 0.2 0.088 13.1 0.2 1.1 1 0 0 1 1 1 0 Auxin response factor Urease_gamma PF00547.18 PVD38348.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Urease, gamma subunit TMEM171 PF15471.6 PVD38350.1 - 0.27 10.2 0.3 0.43 9.5 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Zip PF02535.22 PVD38355.1 - 5.1e-30 104.8 0.8 6.1e-30 104.6 0.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PI3_PI4_kinase PF00454.27 PVD38356.1 - 1.1e-51 176.1 0.1 2.2e-51 175.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PVD38356.1 - 2.2e-22 79.7 12.0 5.7e-22 78.4 12.0 1.7 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 PVD38356.1 - 3e-12 46.1 0.2 8.1e-12 44.8 0.2 1.8 1 0 0 1 1 1 1 FATC domain EFhand_Ca_insen PF08726.10 PVD38356.1 - 0.073 13.2 0.0 0.33 11.1 0.0 2.1 1 0 0 1 1 1 0 Ca2+ insensitive EF hand NUC194 PF08163.12 PVD38357.1 - 1e-137 459.2 8.8 2.2e-137 458.1 8.8 1.6 1 0 0 1 1 1 1 NUC194 domain Tubulin PF00091.25 PVD38358.1 - 6.4e-34 117.9 0.8 7.6e-33 114.4 0.8 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Cyclin_N PF00134.23 PVD38359.1 - 1.9e-25 89.0 0.0 4.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PVD38359.1 - 9.4e-21 74.1 0.1 2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box-like PF12937.7 PVD38359.1 - 3.3e-06 26.9 0.2 9.6e-06 25.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD38359.1 - 0.0003 20.6 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain ABC2_membrane_3 PF12698.7 PVD38360.1 - 9.3e-19 67.7 20.1 1.4e-18 67.2 20.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 PVD38360.1 - 4.3e-08 33.8 0.0 8.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PVD38360.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 PVD38361.1 - 2.7e-32 112.2 19.8 3.3e-32 111.9 19.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 PVD38361.1 - 0.22 10.9 29.0 0.085 12.3 26.2 1.7 1 1 1 2 2 2 0 ABC-2 type transporter Myc_target_1 PF15179.6 PVD38361.1 - 0.62 9.9 2.8 1.1 9.1 2.8 1.4 1 0 0 1 1 1 0 Myc target protein 1 Metallophos PF00149.28 PVD38362.1 - 1.4e-37 130.2 0.2 1.7e-37 129.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PVD38362.1 - 2.5e-18 66.2 2.3 4e-18 65.6 2.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DNA_binding_1 PF01035.20 PVD38363.1 - 4e-23 81.3 0.0 6.4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain UCH PF00443.29 PVD38364.1 - 1.9e-58 198.0 0.3 1.9e-58 198.0 0.3 3.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.19 PVD38364.1 - 6.1e-40 136.3 3.5 1.5e-39 135.0 0.1 2.7 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.8 PVD38364.1 - 3.5e-39 133.2 3.7 3.5e-39 133.2 3.7 2.6 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 PVD38364.1 - 3.2e-16 59.2 11.2 3.2e-16 59.2 11.2 2.3 3 0 0 3 3 3 1 FYVE zinc finger UCH_1 PF13423.6 PVD38364.1 - 3e-05 23.8 3.7 0.0015 18.1 0.0 4.8 5 2 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PVD38364.1 - 0.065 13.2 5.7 0.28 11.2 5.7 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif C1_1 PF00130.22 PVD38364.1 - 10 6.1 11.1 7.9 6.5 7.0 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF938 PF06080.12 PVD38365.1 - 1.1e-23 84.0 0.1 1.6e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF938) FAM195 PF14799.6 PVD38366.1 - 3.4e-29 101.2 1.6 4.4e-29 100.9 1.6 1.1 1 0 0 1 1 1 1 FAM195 family DUF4795 PF16043.5 PVD38367.1 - 1.3e-47 162.1 5.3 1.3e-47 162.1 5.3 3.6 2 2 1 3 3 3 1 Domain of unknown function (DUF4795) DUF3287 PF11690.8 PVD38367.1 - 0.044 13.5 0.1 0.19 11.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Cob_adeno_trans PF01923.18 PVD38367.1 - 0.53 10.4 14.4 0.04 14.1 1.2 3.4 3 1 0 3 3 3 0 Cobalamin adenosyltransferase DUF724 PF05266.14 PVD38367.1 - 1.6 8.5 30.4 0.19 11.5 4.8 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) 7tm_1 PF00001.21 PVD38368.1 - 1.3e-45 155.8 24.1 4.7e-35 121.2 7.0 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD38368.1 - 3.2e-11 43.5 2.9 3.2e-11 43.5 2.9 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD38368.1 - 1.7e-05 24.4 24.2 0.0003 20.3 8.0 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD38368.1 - 0.0002 21.1 6.9 0.0002 21.1 6.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD38369.1 - 1e-13 51.3 9.9 5.2e-12 45.7 5.3 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD38370.1 - 8.9e-19 67.8 1.9 1.1e-18 67.6 1.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Bax1-I PF01027.20 PVD38372.1 - 2.3e-39 135.4 10.9 3.5e-39 134.8 10.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FMN_dh PF01070.18 PVD38372.1 - 0.006 15.7 0.5 1.4 7.9 0.0 2.2 1 1 1 2 2 2 2 FMN-dependent dehydrogenase 7tm_1 PF00001.21 PVD38373.1 - 6.9e-34 117.4 20.5 8.8e-34 117.0 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD38373.1 - 1.5e-07 31.3 22.3 1.6e-07 31.2 21.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD38373.1 - 4.4e-07 29.6 23.9 1e-06 28.3 23.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SIT PF15330.6 PVD38373.1 - 0.58 10.6 3.2 1.3 9.5 3.2 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Glyco_hydro_31 PF01055.26 PVD38374.1 - 3e-300 995.6 6.8 2.1e-154 515.0 3.5 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PVD38374.1 - 1.2e-62 209.2 0.7 4.8e-30 104.1 0.3 2.4 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 PVD38374.1 - 4.7e-25 87.7 9.0 3.6e-13 49.6 0.2 4.3 5 0 0 5 5 5 2 Galactose mutarotase-like Trefoil PF00088.18 PVD38374.1 - 1.6e-21 75.9 27.0 1.7e-10 40.6 9.6 2.8 2 0 0 2 2 2 2 Trefoil (P-type) domain DUF5110 PF17137.4 PVD38374.1 - 0.0016 18.7 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) p450 PF00067.22 PVD38375.1 - 3.5e-35 121.7 3.9 3.8e-34 118.2 2.1 2.4 1 1 1 2 2 2 1 Cytochrome P450 DUF4806 PF16064.5 PVD38375.1 - 8.4e-09 35.6 0.0 4.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) Pox_EPC_I2-L1 PF12575.8 PVD38375.1 - 0.04 14.2 0.9 0.22 11.8 0.4 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Sec2p PF06428.11 PVD38375.1 - 0.041 13.8 7.7 0.078 13.0 7.7 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p p450 PF00067.22 PVD38376.1 - 5e-160 533.2 3.9 1.1e-79 268.4 0.9 2.1 1 1 1 2 2 2 2 Cytochrome P450 CpcD PF01383.21 PVD38376.1 - 0.00025 21.2 0.1 0.24 11.7 0.1 2.6 2 0 0 2 2 2 2 CpcD/allophycocyanin linker domain DUF4466 PF14725.6 PVD38376.1 - 0.013 15.0 1.0 2.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4466) DUF4199 PF13858.6 PVD38376.1 - 0.11 12.9 5.3 3.7 7.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Plasmo_rep PF12135.8 PVD38376.1 - 0.18 11.4 0.2 28 4.4 0.0 2.6 2 0 0 2 2 2 0 Plasmodium repeat family p450 PF00067.22 PVD38377.1 - 1.3e-64 218.7 0.2 1.7e-64 218.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_IE2_3 PF03361.14 PVD38377.1 - 0.037 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 p450 PF00067.22 PVD38378.1 - 1.3e-77 261.6 0.8 1.5e-77 261.3 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38379.1 - 5.2e-147 490.3 2.3 7.6e-90 301.9 0.0 4.0 2 1 2 4 4 4 4 Cytochrome P450 DUF1137 PF06587.11 PVD38379.1 - 0.069 13.2 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) p450 PF00067.22 PVD38380.1 - 5.5e-60 203.4 0.1 6.3e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38381.1 - 2.8e-68 230.8 0.0 3.3e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38382.1 - 1.1e-73 248.6 0.0 1.2e-73 248.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5321 PF17254.2 PVD38382.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) p450 PF00067.22 PVD38383.1 - 3.8e-63 213.8 0.1 4.5e-63 213.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38384.1 - 2.9e-136 454.9 0.4 2.9e-68 230.7 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 DUF5321 PF17254.2 PVD38384.1 - 0.0012 18.3 0.2 2.2 7.7 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5321) Synaptonemal_3 PF15191.6 PVD38384.1 - 0.036 13.8 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 UPF0154 PF03672.13 PVD38384.1 - 0.06 13.4 0.2 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Synaptobrevin PF00957.21 PVD38384.1 - 0.11 12.4 0.9 16 5.4 0.1 2.7 2 0 0 2 2 2 0 Synaptobrevin IKKbetaNEMObind PF12179.8 PVD38384.1 - 0.2 11.7 0.1 28 4.9 0.0 3.7 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain Ribosomal_L9_N PF01281.19 PVD38384.1 - 0.21 11.1 0.8 8.8 6.0 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain Rrf2 PF02082.20 PVD38384.1 - 0.61 10.5 3.0 1.8 8.9 0.3 2.9 3 0 0 3 3 3 0 Transcriptional regulator p450 PF00067.22 PVD38385.1 - 3.1e-62 210.8 0.0 3.8e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38386.1 - 6.5e-76 255.9 1.0 1.5e-74 251.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD38387.1 - 3.2e-68 230.6 0.1 1.3e-66 225.3 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38388.1 - 4.4e-85 286.2 0.0 5.2e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EcoEI_R_C PF08463.10 PVD38388.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 EcoEI R protein C-terminal Synaptonemal_3 PF15191.6 PVD38388.1 - 0.16 11.7 0.3 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 p450 PF00067.22 PVD38389.1 - 9.4e-72 242.2 0.1 3.9e-70 236.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF3231 PF11553.8 PVD38389.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) p450 PF00067.22 PVD38390.1 - 1.3e-62 212.1 0.3 3.2e-62 210.8 0.3 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38391.1 - 2.2e-74 250.9 0.0 2.6e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PVD38392.1 - 7e-69 232.7 0.0 9.8e-61 205.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD38393.1 - 4.5e-63 213.6 0.0 1e-59 202.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 PVD38394.1 - 1.1e-136 456.2 0.1 6.7e-75 252.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_2 PF13347.6 PVD38395.1 - 1.6e-28 99.4 14.2 3.4e-28 98.4 14.2 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 PVD38395.1 - 2.4e-08 33.3 12.5 5.2e-08 32.2 12.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 PVD38396.1 - 1.6e-38 132.6 27.2 3.8e-36 124.7 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 PVD38396.1 - 0.0024 17.0 0.5 0.0024 17.0 0.5 1.6 2 0 0 2 2 2 1 PUCC protein MFS_1_like PF12832.7 PVD38396.1 - 0.59 8.9 16.3 0.016 14.1 2.7 2.4 1 1 1 2 2 2 0 MFS_1 like family Dynamin_N PF00350.23 PVD38397.1 - 0.0012 18.9 2.3 0.0013 18.8 2.3 1.0 1 0 0 1 1 1 1 Dynamin family YL1 PF05764.13 PVD38397.1 - 0.0014 18.8 18.9 0.0015 18.7 18.9 1.0 1 0 0 1 1 1 1 YL1 nuclear protein PTPRCAP PF15713.5 PVD38397.1 - 0.0022 18.3 17.1 0.0025 18.1 17.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Sporozoite_P67 PF05642.11 PVD38397.1 - 0.0054 14.9 12.8 0.0059 14.8 12.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SDA1 PF05285.12 PVD38397.1 - 0.011 15.2 20.4 0.011 15.2 20.4 1.0 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 PVD38397.1 - 0.017 14.4 17.0 0.02 14.3 17.0 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 PVD38397.1 - 0.018 13.3 19.6 0.019 13.3 19.6 1.0 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 PVD38397.1 - 0.021 14.8 27.2 0.024 14.6 27.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 PVD38397.1 - 0.023 12.8 22.7 0.025 12.7 22.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 PVD38397.1 - 0.032 13.4 23.5 0.036 13.2 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SMN PF06003.12 PVD38397.1 - 0.033 13.4 7.1 0.038 13.3 7.1 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TRAP_alpha PF03896.16 PVD38397.1 - 0.035 13.3 9.9 0.035 13.3 9.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.6 PVD38397.1 - 0.035 14.3 7.9 0.04 14.1 7.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 PVD38397.1 - 0.036 12.4 19.2 0.039 12.3 19.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 PVD38397.1 - 0.042 12.3 23.5 0.047 12.1 23.5 1.0 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 PVD38397.1 - 0.062 12.7 19.6 0.065 12.6 19.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 PVD38397.1 - 0.073 11.8 11.1 0.077 11.8 11.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIF_alpha PF05793.12 PVD38397.1 - 0.098 11.2 21.5 0.1 11.2 21.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpc4 PF05132.14 PVD38397.1 - 0.24 11.8 10.9 0.28 11.6 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cnd2 PF05786.14 PVD38397.1 - 0.29 9.7 16.9 0.35 9.5 16.9 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Roughex PF06020.11 PVD38397.1 - 0.31 10.1 13.3 0.36 9.9 13.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RR_TM4-6 PF06459.12 PVD38397.1 - 0.37 10.6 15.9 0.43 10.4 15.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BTV_NS2 PF04514.12 PVD38397.1 - 0.38 9.5 6.4 0.41 9.4 6.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PI3K_1B_p101 PF10486.9 PVD38397.1 - 0.44 8.3 7.6 0.47 8.2 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MCM_bind PF09739.9 PVD38397.1 - 0.45 8.9 9.2 0.46 8.9 9.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4637 PF15470.6 PVD38397.1 - 0.46 10.2 17.2 0.58 9.9 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF719 PF05334.13 PVD38397.1 - 0.5 10.5 8.4 0.64 10.2 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) SpoIIP PF07454.11 PVD38397.1 - 0.51 9.8 12.8 0.57 9.6 12.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GEN1_C PF18380.1 PVD38397.1 - 0.51 11.3 14.9 0.68 10.8 14.9 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain HSP90 PF00183.18 PVD38397.1 - 0.52 9.1 16.8 0.61 8.9 16.8 1.0 1 0 0 1 1 1 0 Hsp90 protein Sigma70_ner PF04546.13 PVD38397.1 - 0.56 10.0 17.3 0.64 9.9 17.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DDHD PF02862.17 PVD38397.1 - 0.66 10.1 5.3 0.66 10.1 5.3 1.1 1 0 0 1 1 1 0 DDHD domain LAP1C PF05609.12 PVD38397.1 - 0.67 9.0 10.7 0.68 8.9 10.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4746 PF15928.5 PVD38397.1 - 0.71 9.2 14.1 0.81 9.1 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 PVD38397.1 - 0.95 9.8 18.2 1.1 9.6 18.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 PVD38397.1 - 0.99 8.1 10.6 1 8.0 10.6 1.0 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 PVD38397.1 - 1 9.1 17.2 1.2 8.9 17.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CSG2 PF16965.5 PVD38397.1 - 1.1 8.2 3.8 1.1 8.1 3.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2151 PF10221.9 PVD38397.1 - 1.1 7.8 8.8 1.2 7.7 8.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator TFB6 PF17110.5 PVD38397.1 - 1.2 8.9 13.2 1.6 8.4 13.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC27 PF09507.10 PVD38397.1 - 1.3 8.4 18.9 1.5 8.2 18.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1980 PF09323.10 PVD38397.1 - 1.4 8.8 8.1 1.6 8.6 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SLC12 PF03522.15 PVD38397.1 - 1.4 7.9 7.2 1.4 7.9 7.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 PVD38397.1 - 1.4 7.7 9.9 1.4 7.7 9.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_polI_A34 PF08208.11 PVD38397.1 - 1.5 8.9 19.1 1.7 8.7 19.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YqfQ PF14181.6 PVD38397.1 - 1.9 8.7 12.1 2.2 8.4 12.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein RPN2_C PF18004.1 PVD38397.1 - 2.2 8.2 19.2 2.5 8.0 19.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Paf1 PF03985.13 PVD38397.1 - 2.2 7.2 22.7 2.5 7.0 22.7 1.0 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.11 PVD38397.1 - 2.4 8.2 16.2 3.4 7.7 16.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NPR3 PF03666.13 PVD38397.1 - 3.1 6.5 12.2 3.4 6.4 12.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 PVD38397.1 - 3.2 7.7 9.0 3.7 7.5 9.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 PVD38397.1 - 3.6 6.7 9.4 3.7 6.7 9.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter XAP5 PF04921.14 PVD38397.1 - 3.6 7.3 16.5 4.3 7.1 16.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Afi1 PF07792.12 PVD38397.1 - 3.7 8.0 14.2 4.7 7.7 14.2 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking IFT57 PF10498.9 PVD38397.1 - 3.8 6.4 15.9 4.3 6.2 15.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 G0-G1_switch_2 PF15103.6 PVD38397.1 - 3.9 7.9 7.1 5.3 7.5 7.1 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Sec62 PF03839.16 PVD38397.1 - 4.5 6.7 12.3 5.8 6.4 12.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SGT1 PF07093.11 PVD38397.1 - 6.4 5.1 14.4 7.6 4.8 14.4 1.0 1 0 0 1 1 1 0 SGT1 protein EIIBC-GUT_N PF03612.14 PVD38397.1 - 6.4 6.5 7.5 7.6 6.2 7.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SspB PF04386.13 PVD38397.1 - 6.6 6.6 13.5 8.3 6.3 13.5 1.2 1 0 0 1 1 1 0 Stringent starvation protein B GNAT_acetyltr_2 PF13718.6 PVD38397.1 - 6.8 6.0 7.0 8.1 5.8 7.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF913 PF06025.12 PVD38397.1 - 7.6 5.4 12.6 8.6 5.2 12.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 PVD38397.1 - 8.1 5.2 5.2 8.8 5.0 5.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Carn_acyltransf PF00755.20 PVD38398.1 - 7.6e-163 543.3 0.0 8.7e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1320 PF07030.12 PVD38398.1 - 0.13 12.4 0.8 0.88 9.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1320) WD40 PF00400.32 PVD38399.1 - 3e-08 34.2 1.9 0.93 10.5 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38399.1 - 0.002 18.4 0.3 0.29 11.4 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 PVD38399.1 - 0.022 15.2 0.5 0.069 13.6 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Nucleoporin_N PF08801.11 PVD38399.1 - 0.04 12.7 0.2 11 4.6 0.0 3.9 3 1 0 4 4 4 0 Nup133 N terminal like mRNA_stabil PF13929.6 PVD38399.1 - 0.11 11.5 0.2 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 mRNA stabilisation WD40 PF00400.32 PVD38400.1 - 1.2e-16 60.8 1.1 0.069 14.1 0.1 7.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 PVD38400.1 - 2.9e-07 29.6 0.1 4.6 5.9 0.0 5.5 4 1 1 5 5 5 5 Nup133 N terminal like ANAPC4_WD40 PF12894.7 PVD38400.1 - 0.00022 21.5 1.3 0.15 12.4 0.0 4.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PVD38400.1 - 0.022 13.4 0.5 10 4.6 0.0 3.6 3 2 0 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PVD38401.1 - 0.0031 17.8 0.1 16 5.9 0.0 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PVD38401.1 - 0.0052 15.6 0.5 1.1 7.9 0.0 3.2 3 0 0 3 3 3 1 Nup133 N terminal like WD40 PF00400.32 PVD38401.1 - 0.0076 17.1 7.7 1 10.4 0.0 5.7 8 0 0 8 8 8 1 WD domain, G-beta repeat EF-hand_8 PF13833.6 PVD38401.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 PVD38402.1 - 0.0013 19.5 0.0 3.8 8.5 0.0 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat PXA PF02194.15 PVD38402.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 PXA domain Ras PF00071.22 PVD38403.1 - 9.9e-56 187.8 0.0 1.1e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD38403.1 - 1.1e-22 80.5 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD38403.1 - 3.7e-08 33.0 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 PVD38403.1 - 0.031 14.0 0.3 0.71 9.6 0.0 2.8 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CagD PF16567.5 PVD38403.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD WD40 PF00400.32 PVD38404.1 - 7.6e-08 32.9 4.7 0.00039 21.2 0.1 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38404.1 - 0.0016 18.7 0.0 0.56 10.5 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 PVD38404.1 - 0.011 15.0 0.0 0.076 12.3 0.0 2.0 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase_Tyr PF07714.17 PVD38405.1 - 5.1e-70 235.7 0.1 7.1e-70 235.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD38405.1 - 4.3e-34 118.1 0.0 7e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sec7 PF01369.20 PVD38406.1 - 1.1e-73 246.8 0.0 1.4e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 PVD38406.1 - 1.1e-27 96.5 0.2 1.9e-27 95.9 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PVD38406.1 - 2.7e-07 31.0 0.2 5.5e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PVD38406.1 - 0.036 14.3 0.1 0.25 11.6 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 PVD38406.1 - 0.04 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 PH domain UCH PF00443.29 PVD38407.1 - 1.5e-52 178.7 2.4 1.5e-52 178.7 2.4 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PVD38407.1 - 5.1e-16 59.1 8.1 2.2e-11 43.9 0.4 4.0 4 1 1 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase YppF PF14178.6 PVD38408.1 - 0.2 11.5 1.5 0.67 9.9 0.2 2.4 3 0 0 3 3 3 0 YppF-like protein SEA PF01390.20 PVD38409.1 - 2.5e-09 37.2 0.4 9.3e-09 35.3 0.4 2.1 1 0 0 1 1 1 1 SEA domain REJ PF02010.15 PVD38410.1 - 2.4e-62 211.2 0.0 8.2e-61 206.2 0.0 2.8 3 0 0 3 3 3 1 REJ domain PKD PF00801.20 PVD38410.1 - 2e-31 107.7 19.1 2.4e-11 43.3 0.0 7.6 7 0 0 7 7 7 6 PKD domain EGF_CA PF07645.15 PVD38410.1 - 8.9e-16 57.8 35.6 2.1e-07 31.0 8.0 3.5 3 0 0 3 3 3 3 Calcium-binding EGF domain hEGF PF12661.7 PVD38410.1 - 2.2e-07 31.3 32.1 0.0023 18.5 7.0 3.8 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_3 PF12947.7 PVD38410.1 - 1.3e-06 28.5 31.8 0.0063 16.7 4.7 3.5 3 0 0 3 3 3 3 EGF domain EGF_MSP1_1 PF12946.7 PVD38410.1 - 4.4e-05 23.4 26.9 0.0009 19.2 5.1 3.8 3 0 0 3 3 3 2 MSP1 EGF domain 1 EGF PF00008.27 PVD38410.1 - 0.0051 17.1 37.4 0.0056 17.0 5.7 3.6 3 0 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 PVD38410.1 - 0.044 14.1 26.2 0.38 11.1 4.3 3.5 3 0 0 3 3 3 0 Pvs28 EGF domain DUF2717 PF10911.8 PVD38410.1 - 0.049 13.3 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) DUF3357 PF11837.8 PVD38410.1 - 0.1 13.0 0.4 0.34 11.4 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) cEGF PF12662.7 PVD38410.1 - 0.83 9.6 33.9 0.47 10.4 1.3 4.3 4 0 0 4 4 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 PVD38410.1 - 7.6 6.9 36.2 0.065 13.5 4.7 3.6 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site PKD_channel PF08016.12 PVD38411.1 - 4.7e-68 229.8 23.8 2.7e-42 145.0 18.0 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 PVD38411.1 - 2.4e-14 53.2 18.5 7.5e-14 51.6 18.5 1.9 1 0 0 1 1 1 1 Ion transport protein PLAT PF01477.23 PVD38411.1 - 3.4e-13 50.2 0.0 6.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain GPS PF01825.21 PVD38411.1 - 6.2e-10 39.5 7.8 6.2e-10 39.5 7.8 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif ANF_receptor PF01094.28 PVD38412.1 - 0.00012 21.4 0.0 0.00014 21.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 PVD38413.1 - 1e-29 103.8 0.0 2.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD38413.1 - 3.3e-09 36.4 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD38413.1 - 2.3e-07 30.4 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 PVD38413.1 - 0.023 14.4 0.0 0.17 11.5 0.0 1.9 1 1 0 1 1 1 0 Periplasmic binding protein Vps26 PF03643.15 PVD38413.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 HNOBA PF07701.14 PVD38414.1 - 6.5e-07 29.0 2.4 6.8e-07 29.0 2.4 1.0 1 0 0 1 1 1 1 Heme NO binding associated Gal4_dimer PF03902.13 PVD38414.1 - 0.055 13.6 0.8 0.48 10.6 0.5 2.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain Peptidase_M13_N PF05649.13 PVD38415.1 - 3.7e-06 26.9 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 ANF_receptor PF01094.28 PVD38417.1 - 0.023 13.8 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Guanylate_cyc PF00211.20 PVD38418.1 - 9.7e-36 123.1 0.2 3.5e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD38418.1 - 5.7e-34 117.6 0.0 9.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD38418.1 - 4.9e-31 108.0 0.0 1.2e-30 106.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 PVD38418.1 - 4.6e-05 23.0 2.7 8e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 PVD38419.1 - 1.2e-66 223.8 0.2 3e-66 222.5 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PVD38419.1 - 0.00037 20.0 0.3 0.00037 20.0 0.3 1.9 2 1 0 2 2 2 1 Heme NO binding associated SR-25 PF10500.9 PVD38419.1 - 0.6 9.7 13.2 1.1 8.8 13.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANF_receptor PF01094.28 PVD38420.1 - 3.8e-44 151.2 0.2 1.1e-28 100.4 0.1 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region Pkinase_Tyr PF07714.17 PVD38420.1 - 7e-39 133.7 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD38420.1 - 1.6e-31 109.6 0.0 3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ephrin_rec_like PF07699.13 PVD38421.1 - 1.4e-81 268.0 200.8 2.2e-11 43.3 3.6 17.5 14 1 3 17 17 17 14 Putative ephrin-receptor like EGF PF00008.27 PVD38421.1 - 1.4e-36 124.4 203.2 2.7e-07 30.7 9.8 17.7 14 0 0 14 14 14 12 EGF-like domain Laminin_G_3 PF13385.6 PVD38421.1 - 1.7e-10 41.3 0.7 4.3e-10 39.9 0.7 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 PVD38421.1 - 1.7e-08 34.7 185.9 0.0035 17.9 5.0 20.1 17 2 0 17 17 17 10 Human growth factor-like EGF EGF_3 PF12947.7 PVD38421.1 - 0.0025 18.0 5.1 0.0025 18.0 5.1 18.5 15 3 3 18 18 18 6 EGF domain Sushi PF00084.20 PVD38422.1 - 1.9e-40 137.3 114.0 1.7e-14 54.1 1.5 15.1 16 0 0 16 16 16 7 Sushi repeat (SCR repeat) EGF PF00008.27 PVD38422.1 - 7.4e-29 99.7 244.7 1.8e-07 31.3 8.6 19.4 17 0 0 17 17 17 12 EGF-like domain EGF_CA PF07645.15 PVD38422.1 - 4e-10 39.7 29.3 1.3e-07 31.7 11.2 23.5 15 6 11 26 26 26 5 Calcium-binding EGF domain hEGF PF12661.7 PVD38422.1 - 3.6e-09 36.9 216.3 0.0063 17.1 0.8 22.5 20 1 0 20 20 20 11 Human growth factor-like EGF Ldl_recept_a PF00057.18 PVD38422.1 - 6e-09 36.0 7.9 6e-09 36.0 7.9 8.5 8 1 1 9 9 9 1 Low-density lipoprotein receptor domain class A Laminin_G_3 PF13385.6 PVD38422.1 - 6.6e-07 29.6 1.5 6.2e-05 23.2 0.4 3.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily HYR PF02494.16 PVD38422.1 - 6.8e-07 29.5 6.4 0.0027 18.0 0.2 3.8 3 0 0 3 3 3 2 HYR domain cEGF PF12662.7 PVD38422.1 - 0.0008 19.3 1.5 0.0008 19.3 1.5 25.9 27 1 0 27 27 27 9 Complement Clr-like EGF-like EGF_3 PF12947.7 PVD38422.1 - 0.0039 17.3 5.4 0.0039 17.3 5.4 20.2 17 2 2 19 19 19 6 EGF domain Ephrin_rec_like PF07699.13 PVD38423.1 - 2.1e-178 578.0 447.4 5.5e-13 48.5 5.8 29.7 27 4 4 31 31 27 25 Putative ephrin-receptor like EGF PF00008.27 PVD38423.1 - 2.4e-33 114.0 228.8 4.9e-07 29.9 10.1 19.2 16 0 0 16 16 15 13 EGF-like domain Sushi PF00084.20 PVD38423.1 - 2.9e-23 82.2 16.7 2.2e-14 53.8 1.6 18.9 19 0 0 19 19 16 6 Sushi repeat (SCR repeat) Laminin_G_3 PF13385.6 PVD38423.1 - 1.1e-09 38.6 1.2 3e-09 37.2 1.2 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HYR PF02494.16 PVD38423.1 - 2e-05 24.8 9.1 0.026 14.8 0.1 4.0 4 0 0 4 4 4 2 HYR domain hEGF PF12661.7 PVD38423.1 - 6.2e-05 23.5 219.8 0.003 18.1 0.7 23.5 19 1 0 19 19 17 11 Human growth factor-like EGF cEGF PF12662.7 PVD38423.1 - 0.0021 18.0 1.7 0.0021 18.0 1.7 31.7 35 0 0 35 35 34 7 Complement Clr-like EGF-like EphA2_TM PF14575.6 PVD38423.1 - 0.044 14.7 0.3 0.19 12.6 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4051 PF13260.6 PVD38423.1 - 0.11 12.2 0.3 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Adeno_E3_CR2 PF02439.15 PVD38423.1 - 0.29 10.9 1.7 0.66 9.8 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DIM PF08194.12 PVD38423.1 - 0.58 10.4 3.6 4.8 7.5 3.6 2.8 1 0 0 1 1 1 0 DIM protein DUF4464 PF14713.6 PVD38424.1 - 2.3e-100 334.8 0.7 2.6e-100 334.6 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF1147 PF06615.11 PVD38427.1 - 0.11 12.5 1.2 0.27 11.3 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1147) TGF_beta PF00019.20 PVD38430.1 - 4.6e-30 104.7 0.2 9.1e-30 103.7 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain HEAT_EZ PF13513.6 PVD38431.1 - 2.7e-21 75.6 7.2 4.6e-10 39.8 0.0 9.7 10 1 1 11 11 10 3 HEAT-like repeat HEAT PF02985.22 PVD38431.1 - 2.2e-18 64.8 8.9 0.0001 22.3 0.0 8.8 9 0 0 9 9 9 3 HEAT repeat IBN_N PF03810.19 PVD38431.1 - 3.1e-10 39.8 4.7 1.7e-09 37.4 0.4 3.7 3 1 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 PVD38431.1 - 4.5e-09 36.6 1.4 0.00091 19.6 0.0 5.9 3 2 3 6 6 6 2 HEAT repeats Cnd1 PF12717.7 PVD38431.1 - 7.8e-08 32.5 2.9 4.3e-06 26.9 0.1 3.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PVD38431.1 - 7e-07 29.1 6.7 0.014 15.4 0.0 5.4 4 1 1 5 5 5 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 PVD38431.1 - 1.6e-05 24.2 5.0 0.11 11.6 0.1 4.2 3 1 2 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 PVD38431.1 - 0.00079 19.1 2.9 0.12 11.9 0.0 4.2 2 1 1 4 4 4 1 CLASP N terminal ParcG PF10274.9 PVD38431.1 - 0.0018 18.4 2.3 0.1 12.7 0.0 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein Cnd3 PF12719.7 PVD38431.1 - 0.011 14.9 0.6 0.11 11.7 0.0 2.9 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 PVD38431.1 - 0.021 14.9 4.0 0.14 12.3 0.1 3.5 3 1 0 3 3 3 0 V-ATPase subunit H IFRD PF05004.13 PVD38431.1 - 0.035 13.2 3.2 11 5.0 0.1 3.8 2 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Brix PF04427.18 PVD38432.1 - 1.7e-10 41.3 2.8 1.7e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Brix domain CBFB_NFYA PF02045.15 PVD38432.1 - 0.38 11.4 6.7 0.74 10.5 6.7 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Presenilin PF01080.17 PVD38434.1 - 0.076 11.8 29.5 0.078 11.7 29.5 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 PVD38434.1 - 0.63 8.3 40.3 0.83 7.9 40.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 PVD38434.1 - 0.77 8.5 35.3 0.79 8.5 35.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 PVD38434.1 - 1.9 7.5 21.5 2.1 7.3 21.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 PVD38434.1 - 6.2 5.6 24.6 6.1 5.6 24.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 PVD38434.1 - 8.7 5.2 33.7 9.6 5.1 33.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BTB PF00651.31 PVD38435.1 - 3e-06 27.4 0.0 6.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PVD38435.1 - 2.1e-05 24.5 2.1 0.0019 18.3 1.3 2.8 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4478 PF14793.6 PVD38435.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases BrnT_toxin PF04365.13 PVD38435.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Metallophos PF00149.28 PVD38436.1 - 6.4e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DHC_N1 PF08385.12 PVD38437.1 - 4.9e-22 78.3 0.0 6.3e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 PVD38438.1 - 4.9e-124 413.5 0.0 3.3e-61 207.0 0.0 3.9 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD38438.1 - 3.6e-102 342.4 21.5 4.4e-92 309.2 11.9 5.3 6 1 1 7 7 7 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PVD38438.1 - 8.6e-96 320.2 0.3 3.1e-95 318.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 PVD38438.1 - 1.9e-94 316.5 23.8 7.9e-61 206.0 12.9 2.8 2 1 1 3 3 3 2 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 PVD38438.1 - 3.8e-78 263.5 0.9 5.9e-69 233.2 0.1 4.5 3 2 1 4 4 3 2 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 PVD38438.1 - 9.2e-75 250.1 0.7 4.8e-69 231.5 0.2 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_1 PF17857.1 PVD38438.1 - 1.5e-42 143.8 0.8 1.5e-42 143.8 0.8 3.7 3 0 0 3 3 3 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 PVD38438.1 - 7e-27 94.1 1.1 7.3e-26 90.8 0.3 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD38438.1 - 4.2e-24 85.1 0.0 1.6e-13 50.9 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PVD38438.1 - 2e-08 34.8 0.3 0.071 13.5 0.0 5.3 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 PVD38438.1 - 1.1e-07 32.2 0.1 0.12 12.7 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 PVD38438.1 - 2.2e-05 24.9 1.0 0.37 11.2 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PVD38438.1 - 5.6e-05 22.9 0.5 1.3 8.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 PVD38438.1 - 8.7e-05 23.1 0.3 0.64 10.6 0.0 4.6 4 0 0 4 4 3 1 AAA domain PhoH PF02562.16 PVD38438.1 - 0.00021 20.8 0.3 0.24 10.8 0.0 3.5 3 0 0 3 3 3 1 PhoH-like protein RNA_helicase PF00910.22 PVD38438.1 - 0.00036 20.9 0.0 13 6.3 0.0 4.4 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 PVD38438.1 - 0.0006 20.3 0.9 3.3 8.2 0.0 5.0 5 0 0 5 5 4 1 ABC transporter FAM167 PF11652.8 PVD38438.1 - 0.0026 18.2 3.5 0.91 10.0 1.7 5.0 3 1 0 3 3 3 1 FAM167 AAA_19 PF13245.6 PVD38438.1 - 0.0029 17.9 4.6 1.2 9.5 0.0 4.4 5 0 0 5 5 3 1 AAA domain Mg_chelatase PF01078.21 PVD38438.1 - 0.0047 16.3 0.2 5.3 6.4 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PVD38438.1 - 0.0053 16.7 0.0 0.35 10.8 0.0 3.1 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.26 PVD38438.1 - 0.0096 15.6 0.0 3.6 7.3 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 PVD38438.1 - 0.011 15.7 0.7 2.2 8.3 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 PVD38438.1 - 0.014 15.1 0.0 2.9 7.6 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 PVD38438.1 - 0.024 13.7 0.0 0.37 9.8 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 PVD38438.1 - 0.073 12.8 0.3 54 3.6 0.1 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATPase PF06745.13 PVD38438.1 - 0.082 12.2 2.5 20 4.4 1.7 3.4 3 0 0 3 3 2 0 KaiC ATP_bind_1 PF03029.17 PVD38438.1 - 0.09 12.5 3.6 1.3 8.8 0.0 4.2 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 PVD38438.1 - 0.11 12.7 0.5 73 3.5 0.0 4.1 4 0 0 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 PVD38438.1 - 0.13 12.4 0.1 57 3.8 0.0 3.7 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 PVD38438.1 - 0.2 11.2 0.6 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain DASH_Duo1 PF08651.10 PVD38438.1 - 0.33 10.7 4.6 50 3.8 0.2 5.7 4 0 0 4 4 4 0 DASH complex subunit Duo1 GSCFA PF08885.11 PVD38438.1 - 1.6 8.4 5.6 13 5.4 0.1 3.7 3 0 0 3 3 3 0 GSCFA family DUF2570 PF10828.8 PVD38438.1 - 3 7.7 11.6 2.4 8.0 7.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) NPV_P10 PF05531.12 PVD38438.1 - 3.1 8.3 15.9 53 4.4 0.4 6.3 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_lid_11 PF18198.1 PVD38439.1 - 1.1e-51 174.9 0.0 1.9e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 PVD38439.1 - 4.7e-44 150.2 4.5 1e-43 149.0 4.5 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 PVD38439.1 - 6.2e-38 129.5 0.0 2.2e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 PVD38439.1 - 1.9e-15 56.9 0.0 3.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_C PF18199.1 PVD38440.1 - 8.8e-55 186.1 0.2 1e-54 185.8 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Integrase_H2C2 PF17921.1 PVD38443.1 - 1.2e-21 76.5 4.4 6.3e-10 39.0 0.4 4.2 3 0 0 3 3 3 2 Integrase zinc binding domain zf-H2C2_2 PF13465.6 PVD38443.1 - 1.7e-08 34.5 31.1 8.6e-05 22.8 0.9 6.3 7 0 0 7 7 6 3 Zinc-finger double domain zf-H2C2 PF09337.10 PVD38443.1 - 5.3e-08 32.9 4.0 4.4e-05 23.6 0.3 3.4 3 0 0 3 3 2 2 H2C2 zinc finger zf-C2H2 PF00096.26 PVD38443.1 - 0.0003 21.1 37.8 0.0013 19.0 3.3 6.0 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD38443.1 - 0.00065 20.3 8.7 0.0077 17.0 0.5 6.6 7 0 0 7 7 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 PVD38443.1 - 0.044 14.1 3.7 2.9 8.3 0.0 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding rve PF00665.26 PVD38443.1 - 0.074 13.2 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain zf-C2HC_2 PF13913.6 PVD38443.1 - 0.2 11.6 15.1 3.4 7.7 0.1 5.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type C1_1 PF00130.22 PVD38443.1 - 0.22 11.5 8.7 3.1 7.7 2.6 3.7 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 PVD38443.1 - 0.51 10.4 8.3 0.35 10.9 4.4 2.6 2 0 0 2 2 2 0 AT hook motif zf-C2H2_jaz PF12171.8 PVD38443.1 - 0.72 10.2 15.6 0.68 10.3 1.0 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 PVD38443.1 - 0.83 10.2 11.9 1.9 9.0 0.2 4.6 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 PVD38443.1 - 2.2 8.5 10.4 40 4.5 0.0 4.9 4 0 0 4 4 4 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 PVD38443.1 - 6.8 6.9 12.8 11 6.2 0.9 4.8 3 1 1 4 4 4 0 Zinc ribbon domain zf-RING_7 PF02591.15 PVD38443.1 - 7.7 6.8 8.1 40 4.5 0.1 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 PVD38443.1 - 9.3 7.1 12.4 4.7 8.0 1.0 4.1 2 1 1 3 3 3 0 zinc-ribbon family Rho_GDI PF02115.17 PVD38444.1 - 8.2e-66 221.5 0.8 9.9e-66 221.2 0.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor AKAP2_C PF15304.6 PVD38444.1 - 0.019 14.3 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Pyr_redox_2 PF07992.14 PVD38445.1 - 1.2e-08 34.6 0.2 1.3e-07 31.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PVD38445.1 - 0.00071 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PVD38445.1 - 0.0036 17.3 0.0 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 PVD38445.1 - 0.015 15.7 0.0 5.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PVD38445.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CbiD PF01888.17 PVD38445.1 - 0.13 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 CbiD HI0933_like PF03486.14 PVD38445.1 - 0.15 10.7 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Sad1_UNC PF07738.13 PVD38446.1 - 1.1e-38 132.2 1.1 3.8e-38 130.5 0.0 2.4 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal Rad51 PF08423.11 PVD38447.1 - 7.9e-73 244.9 0.2 1.1e-72 244.4 0.2 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 PVD38447.1 - 6.3e-10 39.0 0.0 8.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 PVD38447.1 - 2e-06 28.3 0.3 4.3e-06 27.2 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 PVD38447.1 - 3.4e-06 26.8 0.0 6.4e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PVD38447.1 - 6e-05 22.5 0.3 0.00013 21.4 0.0 1.8 2 1 0 2 2 2 1 KaiC NRD1_2 PF01995.16 PVD38447.1 - 0.00021 20.7 0.1 0.00042 19.7 0.1 1.6 2 0 0 2 2 2 1 NrpR regulatory domains NRD1 and 2 Tsc35 PF15079.6 PVD38447.1 - 0.013 15.1 1.3 0.019 14.5 1.3 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 Ribosomal_L7Ae PF01248.26 PVD38448.1 - 2.3e-26 91.3 0.1 2.8e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PVD38448.1 - 0.0009 19.3 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 PVD38448.1 - 0.0034 17.2 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain YadA_stalk PF05662.14 PVD38448.1 - 0.07 13.5 0.8 14 6.1 0.1 2.3 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Na_Ca_ex PF01699.24 PVD38449.1 - 4.8e-27 94.8 5.7 7.3e-27 94.2 5.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Calx-beta PF03160.14 PVD38449.1 - 1e-22 80.1 1.0 3.7e-22 78.4 0.2 2.1 2 0 0 2 2 2 1 Calx-beta domain Glucos_trans_II PF14264.6 PVD38449.1 - 0.00081 18.8 0.0 0.0024 17.3 0.0 1.6 1 1 0 1 1 1 1 Glucosyl transferase GtrII Na_Ca_ex_C PF16494.5 PVD38449.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain DUF4843 PF16132.5 PVD38449.1 - 0.14 11.7 0.1 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Calx-beta PF03160.14 PVD38450.1 - 2.7e-14 53.2 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Calx-beta domain Na_Ca_ex PF01699.24 PVD38450.1 - 8.2e-07 29.1 2.5 1.4e-06 28.4 2.5 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Phage_holin_3_6 PF07332.11 PVD38450.1 - 1.3 9.1 5.7 19 5.3 5.7 2.2 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Rhomboid PF01694.22 PVD38451.1 - 1.7e-30 106.0 10.5 2.2e-30 105.6 10.5 1.2 1 0 0 1 1 1 1 Rhomboid family PRA1 PF03208.19 PVD38451.1 - 1.6 8.3 6.8 0.28 10.8 1.8 2.0 1 1 1 2 2 2 0 PRA1 family protein DUF4735 PF15882.5 PVD38452.1 - 2.3e-70 237.3 0.1 3.1e-70 236.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) Actin PF00022.19 PVD38453.1 - 2.4e-89 299.8 0.0 3.3e-57 194.0 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 PVD38453.1 - 2e-05 23.6 0.0 0.057 12.2 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 PVD38453.1 - 0.0064 16.9 0.0 0.051 14.0 0.0 2.4 2 1 0 2 2 2 1 Cell division protein FtsA Robl_LC7 PF03259.17 PVD38453.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Exo_endo_phos_2 PF14529.6 PVD38454.1 - 0.00038 20.3 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 PVD38455.1 - 1.3e-22 80.4 0.1 1.6e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_4 PF14490.6 PVD38455.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain DUF2511 PF10709.9 PVD38455.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) Ldl_recept_a PF00057.18 PVD38458.1 - 5.7e-213 688.8 518.2 1.5e-12 47.5 12.4 30.8 30 0 0 30 30 27 27 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 PVD38458.1 - 1.3e-139 454.4 92.9 1.6e-10 41.3 0.4 31.2 33 1 0 33 33 32 22 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 PVD38458.1 - 4.6e-32 110.0 351.5 1.7e-09 37.8 10.2 25.9 20 2 5 25 25 19 14 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 PVD38458.1 - 1.3e-18 67.2 2.9 0.025 13.8 0.0 10.1 9 3 1 10 10 10 5 Domain of unknown function (DUF5050) SGL PF08450.12 PVD38458.1 - 2e-15 57.1 27.3 0.0068 16.0 0.1 14.5 10 7 4 14 14 14 6 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 PVD38458.1 - 1.2e-09 37.9 15.6 3.5e-06 26.8 1.0 19.0 18 0 0 18 18 17 6 Complement Clr-like EGF-like EGF PF00008.27 PVD38458.1 - 9.5e-07 29.0 21.4 1.8e-06 28.2 7.3 34.5 38 1 1 39 39 28 8 EGF-like domain hEGF PF12661.7 PVD38458.1 - 0.00044 20.8 5.0 0.00044 20.8 5.0 26.7 32 1 0 32 32 21 5 Human growth factor-like EGF EGF_2 PF07974.13 PVD38458.1 - 0.0023 18.3 8.2 0.0023 18.3 8.2 26.1 27 4 3 30 30 14 3 EGF-like domain PliI PF16743.5 PVD38458.1 - 0.084 12.6 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme SKG6 PF08693.10 PVD38458.1 - 9.1 5.8 11.1 18 4.8 11.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TIR_2 PF13676.6 PVD38459.1 - 2.3e-15 57.2 0.0 3.2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD38459.1 - 6e-11 42.4 0.0 6.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD38460.1 - 6.9e-25 86.6 29.6 1.4e-14 53.6 8.6 6.0 5 2 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 PVD38460.1 - 6.2e-09 36.0 38.1 0.00037 20.8 0.1 7.5 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD38460.1 - 2.9e-06 27.1 30.1 0.13 12.8 0.0 8.8 8 1 1 9 9 9 2 Leucine Rich Repeat LRRNT PF01462.18 PVD38460.1 - 4.8e-05 22.9 1.3 9.4e-05 22.0 1.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PVD38460.1 - 1.6 9.0 28.3 1.9 8.8 0.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 PVD38461.1 - 0.011 15.5 1.3 0.011 15.5 1.3 2.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 PVD38461.1 - 0.32 11.2 1.4 2.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 PVD38461.1 - 7.4 7.5 6.4 8 7.4 0.6 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat TIR PF01582.20 PVD38462.1 - 1.9e-17 63.6 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD38462.1 - 3.5e-17 63.1 0.0 4.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 PVD38462.1 - 0.039 14.3 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF2970 PF11174.8 PVD38462.1 - 0.14 12.0 0.1 25 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Endonuclea_NS_2 PF13930.6 PVD38462.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease LRR_8 PF13855.6 PVD38463.1 - 3e-18 65.3 22.3 6.2e-09 35.5 0.1 4.8 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PVD38463.1 - 5.7e-12 45.6 23.8 2.9e-05 24.3 0.3 5.7 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD38463.1 - 0.0052 17.2 25.2 0.041 14.4 0.1 7.3 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 PVD38463.1 - 0.019 14.9 22.4 1.5 9.1 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 PVD38464.1 - 2.3e-26 91.3 22.1 3.1e-10 39.6 2.5 5.6 6 0 0 6 6 6 4 Leucine rich repeat TIR_2 PF13676.6 PVD38464.1 - 2.2e-15 57.3 0.1 1.3e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 PVD38464.1 - 1.4e-14 54.3 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD38464.1 - 1e-10 41.7 23.5 0.00021 21.6 3.4 5.7 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PVD38464.1 - 0.0034 17.3 19.3 3 8.1 0.1 6.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 PVD38464.1 - 0.0081 16.6 27.5 3 8.7 0.0 8.0 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 PVD38465.1 - 2.4e-41 139.3 44.6 1.6e-14 53.4 6.4 8.0 9 1 0 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 PVD38465.1 - 6e-18 64.6 49.5 4e-06 27.1 1.2 10.3 6 4 6 12 12 12 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD38465.1 - 1.3e-17 64.5 0.0 4.1e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 PVD38465.1 - 1.5e-14 54.2 0.0 2.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD38465.1 - 2.8e-09 37.0 7.9 0.0088 16.0 0.6 4.1 4 1 0 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 PVD38465.1 - 1.9e-07 30.5 2.9 1.9e-07 30.5 2.9 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PVD38465.1 - 3.9e-07 29.7 41.4 0.54 11.0 0.0 12.8 13 2 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 PVD38465.1 - 9.7e-07 28.4 49.2 0.17 12.0 0.4 10.9 11 0 0 11 11 11 5 Leucine Rich repeat LRR_8 PF13855.6 PVD38466.1 - 5e-25 87.0 19.6 3.7e-13 49.0 1.8 5.2 5 1 0 5 5 5 4 Leucine rich repeat TIR_2 PF13676.6 PVD38466.1 - 3.1e-17 63.3 0.0 8.7e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 PVD38466.1 - 6.9e-15 54.9 26.0 1.2e-06 28.7 2.1 6.1 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) TIR PF01582.20 PVD38466.1 - 1.2e-14 54.5 0.0 2.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD38466.1 - 1.3e-09 37.3 17.9 0.33 11.7 0.0 9.2 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_5 PF13306.6 PVD38466.1 - 5e-06 26.5 4.4 0.0048 16.8 1.0 3.1 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD38466.1 - 0.00085 18.9 2.8 4.1 6.9 0.0 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 PVD38466.1 - 0.017 15.1 36.3 0.12 12.5 0.4 7.1 7 0 0 7 7 7 0 Leucine Rich repeat TIR_2 PF13676.6 PVD38467.1 - 9.4e-18 64.9 0.0 1.7e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PVD38467.1 - 1.1e-13 51.3 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD38468.1 - 2.7e-10 39.9 2.1 1.6e-05 24.5 0.5 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD38468.1 - 2.2e-06 27.9 4.9 0.0076 16.6 0.2 3.8 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PVD38468.1 - 0.00044 20.4 2.6 5.5 7.9 0.1 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD38468.1 - 0.01 15.8 8.7 2.9 8.2 0.5 4.6 4 1 1 5 5 5 0 Leucine Rich repeat Glyco_hydro_38N PF01074.22 PVD38471.1 - 2.9e-36 125.3 1.4 3.3e-36 125.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38N PF01074.22 PVD38472.1 - 5.4e-17 62.1 0.1 1e-16 61.1 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain DUF5374 PF17344.2 PVD38472.1 - 0.17 11.9 0.7 0.26 11.2 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5374) Glyco_hydro_38C PF07748.13 PVD38473.1 - 7.9e-86 287.5 0.3 5.3e-47 160.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 PVD38473.1 - 6.6e-45 153.7 0.3 2e-40 139.0 0.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro38C2 PF17677.1 PVD38473.1 - 5.6e-19 68.0 0.0 3.6e-12 46.2 0.0 3.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Alpha-mann_mid PF09261.11 PVD38473.1 - 1.4e-11 44.4 0.7 6.2e-10 39.1 0.2 2.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain AbfS_sensor PF18225.1 PVD38473.1 - 0.058 13.3 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain DUF2190 PF09956.9 PVD38473.1 - 0.059 13.8 0.1 0.63 10.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) TMC PF07810.13 PVD38474.1 - 2.5e-36 124.7 0.8 2.5e-36 124.7 0.8 2.7 2 1 0 2 2 2 1 TMC domain DUF2207 PF09972.9 PVD38474.1 - 1.6 7.4 11.0 2.4e+02 0.3 11.0 2.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Bac_export_2 PF01312.19 PVD38474.1 - 5.6 6.1 12.4 0.69 9.1 4.2 3.1 2 1 1 3 3 3 0 FlhB HrpN YscU SpaS Family WD40 PF00400.32 PVD38475.1 - 6.6e-12 45.8 0.4 0.016 16.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38475.1 - 3.5e-09 36.8 0.0 0.0086 16.4 0.0 4.3 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Endotoxin_mid PF09131.10 PVD38475.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain Sec7 PF01369.20 PVD38476.1 - 7.4e-64 214.8 0.4 1.3e-63 214.0 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PVD38476.1 - 3.5e-27 95.2 6.5 3.5e-27 95.2 6.5 3.8 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1045 PF06299.12 PVD38476.1 - 0.056 13.4 0.2 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) DUF4045 PF13254.6 PVD38476.1 - 5.2 6.6 13.8 0.16 11.6 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) BTG PF07742.12 PVD38477.1 - 2.9e-38 130.3 0.0 4.4e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 BTG family Ig_3 PF13927.6 PVD38480.1 - 4.1e-16 59.4 5.7 6.2e-08 33.1 0.2 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 PVD38480.1 - 6.2e-16 58.5 4.7 1.3e-08 35.0 0.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 PVD38480.1 - 1.1e-10 41.6 0.1 0.00056 20.1 0.1 2.2 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 PVD38480.1 - 1.3e-09 38.3 0.1 9.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 PVD38480.1 - 1.9e-07 31.2 7.6 7.9e-05 22.8 0.6 3.6 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 PVD38480.1 - 9.5e-06 25.8 4.5 0.26 11.5 0.1 3.5 2 2 2 4 4 4 3 Immunoglobulin V-set domain I-set PF07679.16 PVD38480.1 - 0.00051 20.0 2.2 0.71 10.0 0.4 3.3 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_C17orf99 PF17736.1 PVD38480.1 - 0.00055 19.9 1.6 0.0018 18.3 0.2 2.5 2 2 0 2 2 2 1 C17orf99 Ig domain BiPBP_C PF06832.12 PVD38480.1 - 0.0042 17.1 0.0 0.096 12.7 0.0 2.2 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 PVD38480.1 - 0.059 12.9 0.0 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Extensin-like_C PF06904.12 PVD38480.1 - 0.066 13.2 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Extensin-like protein C-terminus Izumo-Ig PF16706.5 PVD38480.1 - 0.068 13.2 0.1 5.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 PVD38481.1 - 5.7e-56 186.8 48.4 3.7e-12 46.4 2.8 7.3 6 1 1 7 7 7 7 Immunoglobulin domain Ig_3 PF13927.6 PVD38481.1 - 1.3e-50 169.9 44.5 2.3e-12 47.3 1.4 8.1 7 1 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 PVD38481.1 - 1.2e-31 108.8 54.1 5.6e-08 32.9 2.2 10.2 8 4 0 8 8 8 7 Immunoglobulin domain I-set PF07679.16 PVD38481.1 - 1.3e-25 89.3 27.4 4e-08 33.2 1.4 10.1 7 6 0 7 7 7 5 Immunoglobulin I-set domain Ig_5 PF16681.5 PVD38481.1 - 2.2e-17 63.2 8.2 0.0058 17.0 0.1 6.6 7 0 0 7 7 7 5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 PVD38481.1 - 1.8e-14 53.8 10.5 0.0019 18.4 0.1 6.3 7 0 0 7 7 7 5 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 PVD38481.1 - 2.6e-13 50.1 53.2 0.00016 21.8 0.5 12.8 8 6 6 14 14 14 5 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD38481.1 - 5.5e-11 42.4 0.8 0.0011 19.0 0.1 6.5 7 0 0 7 7 7 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD38481.1 - 5.5e-10 38.7 0.3 0.41 10.2 0.0 6.5 6 0 0 6 6 6 2 Immunoglobulin domain C2-set PF05790.15 PVD38481.1 - 1.3 9.2 13.6 22 5.3 0.3 5.9 5 1 1 6 6 6 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 PVD38481.1 - 3.9 7.3 13.6 20 5.0 1.4 4.9 5 1 0 5 5 5 0 Adenovirus E3 region protein CR1 ig PF00047.25 PVD38482.1 - 8.4e-08 32.3 0.0 0.0027 17.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 PVD38482.1 - 1.7e-06 28.2 0.0 0.029 14.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 PVD38482.1 - 4.3e-06 27.2 0.0 0.037 14.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 PVD38482.1 - 2.3e-05 24.4 0.0 0.014 15.4 0.0 2.1 1 1 1 2 2 2 2 Izumo-like Immunoglobulin domain I-set PF07679.16 PVD38482.1 - 2.6e-05 24.2 0.0 0.046 13.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 PVD38482.1 - 0.00025 21.2 0.1 0.22 11.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 PVD38482.1 - 0.00037 20.0 0.0 0.0095 15.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 PVD38482.1 - 0.055 13.9 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Ig_2 PF13895.6 PVD38483.1 - 2.5e-36 123.9 33.5 6.7e-08 32.8 1.2 8.0 6 1 2 8 8 8 6 Immunoglobulin domain Ig_3 PF13927.6 PVD38483.1 - 1.5e-32 112.0 32.3 5e-06 27.0 1.2 8.2 7 1 1 8 8 8 7 Immunoglobulin domain ig PF00047.25 PVD38483.1 - 1.6e-18 66.6 32.6 0.00042 20.4 1.4 8.5 7 4 1 8 8 8 6 Immunoglobulin domain I-set PF07679.16 PVD38483.1 - 8e-13 48.3 11.8 0.45 10.6 0.0 8.3 6 4 1 7 7 7 6 Immunoglobulin I-set domain V-set PF07686.17 PVD38483.1 - 3.9e-12 46.3 38.8 0.021 15.0 1.8 11.1 5 5 5 10 10 10 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 PVD38483.1 - 2.3e-10 40.4 0.9 0.66 10.1 0.0 6.0 4 2 2 6 6 6 3 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 PVD38483.1 - 4.5e-10 38.9 2.1 0.21 11.1 0.0 7.1 6 1 1 7 7 7 2 Immunoglobulin domain Ig_4 PF16680.5 PVD38483.1 - 8.2e-09 35.6 2.1 8 6.8 0.1 7.1 5 3 2 7 7 7 1 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 PVD38484.1 - 6.4e-31 106.8 33.6 2.3e-07 31.3 0.1 8.4 7 1 1 8 8 8 7 Immunoglobulin domain Ig_2 PF13895.6 PVD38484.1 - 8.2e-31 106.2 42.8 2.6e-07 30.9 0.4 8.8 5 2 2 7 7 7 6 Immunoglobulin domain ig PF00047.25 PVD38484.1 - 3.5e-18 65.5 41.2 0.0027 17.8 0.3 10.3 7 4 1 8 8 8 7 Immunoglobulin domain V-set PF07686.17 PVD38484.1 - 4.5e-13 49.3 34.9 0.21 11.8 2.2 12.4 8 3 3 11 11 11 5 Immunoglobulin V-set domain I-set PF07679.16 PVD38484.1 - 2.4e-09 37.1 12.2 4.2 7.5 0.0 8.4 7 1 0 7 7 7 4 Immunoglobulin I-set domain Ig_6 PF18452.1 PVD38484.1 - 1.6e-08 33.9 4.9 7.2 6.3 0.0 7.2 8 0 0 8 8 8 3 Immunoglobulin domain Izumo-Ig PF16706.5 PVD38484.1 - 2.3e-05 24.4 1.0 2.5 8.2 0.0 6.1 6 1 1 7 7 7 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 PVD38484.1 - 0.0099 16.0 1.1 5.3 7.3 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C2-set domain PKD PF00801.20 PVD38484.1 - 0.02 14.7 1.0 0.02 14.7 1.0 6.7 5 1 0 5 5 5 0 PKD domain VWA_N2 PF16164.5 PVD38484.1 - 0.15 12.3 2.8 0.97 9.6 1.9 2.8 2 0 0 2 2 2 0 VWA N-terminal PCI PF01399.27 PVD38485.1 - 4.4e-20 72.1 0.1 1.9e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain EF_assoc_2 PF08356.12 PVD38486.1 - 4.8e-35 119.4 0.0 1.1e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 PVD38486.1 - 1.2e-25 88.8 0.2 5.3e-25 86.8 0.2 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 PVD38486.1 - 2.7e-24 85.6 0.0 8.4e-19 67.7 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 PVD38486.1 - 8.4e-14 51.8 0.0 2.5e-10 40.6 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD38486.1 - 1.4e-05 24.6 0.0 0.00044 19.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_6 PF13405.6 PVD38486.1 - 1.8e-05 24.3 0.1 0.0061 16.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain PduV-EutP PF10662.9 PVD38486.1 - 2.3e-05 24.2 0.1 0.085 12.6 0.0 2.9 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PVD38486.1 - 2.6e-05 23.8 0.1 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD38486.1 - 4.4e-05 23.5 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 PVD38486.1 - 4.6e-05 23.8 0.1 0.48 10.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD38486.1 - 7.9e-05 21.9 0.3 0.037 13.6 0.0 2.7 2 0 0 2 2 2 1 EF hand AAA_16 PF13191.6 PVD38486.1 - 0.00033 21.1 0.0 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 PVD38486.1 - 0.0031 16.8 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 PVD38486.1 - 0.0035 17.3 1.1 6.4 6.6 0.0 3.8 5 0 0 5 5 4 1 RsgA GTPase AAA_14 PF13173.6 PVD38486.1 - 0.0086 16.1 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PVD38486.1 - 0.012 15.6 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 PVD38486.1 - 0.034 13.9 0.5 0.65 9.7 0.0 2.9 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PVD38486.1 - 0.038 14.3 0.0 2.2 8.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 PVD38486.1 - 0.076 12.5 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 PVD38486.1 - 0.12 11.9 0.0 0.96 8.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 PVD38486.1 - 0.26 10.4 1.4 13 4.8 0.2 3.3 2 1 0 2 2 2 0 G-protein alpha subunit TPT PF03151.16 PVD38487.1 - 1e-14 54.6 10.7 1.4e-14 54.1 10.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Fringe PF02434.16 PVD38488.1 - 5.3e-95 317.6 0.1 6.6e-95 317.3 0.1 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PVD38488.1 - 0.00045 20.1 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase SHE3 PF17078.5 PVD38488.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 SNARE PF05739.19 PVD38489.1 - 5.6e-10 39.1 0.9 5.6e-10 39.1 0.9 1.8 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 PVD38489.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Prominin PF05478.11 PVD38489.1 - 0.079 10.9 0.3 0.1 10.5 0.3 1.1 1 0 0 1 1 1 0 Prominin CobS PF02654.15 PVD38489.1 - 0.084 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Laminin_EGF PF00053.24 PVD38490.1 - 3.9e-12 46.1 13.2 4.9e-12 45.8 13.2 1.1 1 0 0 1 1 1 1 Laminin EGF domain EGF_2 PF07974.13 PVD38490.1 - 0.015 15.7 4.6 0.015 15.7 4.6 2.6 2 1 1 3 3 3 0 EGF-like domain PHF5 PF03660.14 PVD38490.1 - 0.53 10.5 8.3 0.77 10.0 8.3 1.3 1 1 0 1 1 1 0 PHF5-like protein Laminin_N PF00055.17 PVD38494.1 - 2.1e-59 200.9 0.0 2.1e-59 200.9 0.0 2.0 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 PVD38494.1 - 4.8e-07 29.8 14.3 4.8e-07 29.8 14.3 1.7 2 0 0 2 2 2 1 Laminin EGF domain F5_F8_type_C PF00754.25 PVD38494.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 1 0 1 1 1 0 F5/8 type C domain BNR_6 PF15899.5 PVD38494.1 - 0.055 13.6 0.7 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 BNR-Asp box repeat Laminin_N PF00055.17 PVD38495.1 - 2.1e-06 27.5 0.2 2.7e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Secretogranin_V PF05281.11 PVD38495.1 - 0.066 12.8 1.0 0.083 12.5 1.0 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) PKD_channel PF08016.12 PVD38497.1 - 1.8e-70 237.8 13.5 1.8e-70 237.8 13.5 1.8 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 PVD38497.1 - 7.9e-16 58.7 0.0 1.7e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 PVD38497.1 - 6.3e-13 48.5 23.5 6.3e-13 48.5 23.5 3.6 3 1 0 4 4 4 1 Ion transport protein GPS PF01825.21 PVD38497.1 - 0.24 12.0 7.3 0.036 14.6 2.2 2.3 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif Homeodomain PF00046.29 PVD38498.1 - 0.18 11.7 0.1 6.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Homeodomain REJ PF02010.15 PVD38499.1 - 1.2e-08 34.2 0.2 5.8e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 REJ domain REJ PF02010.15 PVD38500.1 - 2.3e-08 33.3 0.0 3.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 REJ domain PKD PF00801.20 PVD38501.1 - 3.7e-05 23.5 4.5 0.2 11.5 0.0 3.8 3 2 0 3 3 3 3 PKD domain PKD_channel PF08016.12 PVD38502.1 - 1.1e-73 248.3 12.2 1.1e-73 248.3 12.2 1.8 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 PVD38502.1 - 2.3e-16 60.4 0.0 7.2e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 PVD38502.1 - 1.2e-12 47.6 23.5 1.2e-12 47.6 23.5 3.5 4 0 0 4 4 4 1 Ion transport protein REJ PF02010.15 PVD38503.1 - 3.4e-33 115.1 2.3 1.3e-26 93.4 0.5 2.2 1 1 1 2 2 2 2 REJ domain SSI PF00720.17 PVD38504.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Subtilisin inhibitor-like PKD PF00801.20 PVD38505.1 - 2.2e-10 40.2 30.7 0.0016 18.2 0.5 7.5 7 1 0 7 7 7 5 PKD domain Inhibitor_I42 PF09394.10 PVD38505.1 - 0.01 16.2 1.1 6 7.3 0.0 3.7 3 0 0 3 3 3 0 Chagasin family peptidase inhibitor I42 ASH PF15780.5 PVD38505.1 - 0.34 11.1 5.9 15 5.8 0.1 3.8 3 1 2 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ArenaCapSnatch PF17296.2 PVD38506.1 - 0.059 12.8 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain PMM PF03332.13 PVD38507.1 - 1.4e-103 345.4 0.8 1.6e-103 345.2 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PVD38507.1 - 1.2e-08 35.1 0.0 5.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PVD38507.1 - 0.042 14.1 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CSD PF00313.22 PVD38508.1 - 3e-14 52.6 0.0 4.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PVD38508.1 - 0.0083 15.8 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain AROS PF15684.5 PVD38509.1 - 4.2e-11 43.5 21.3 9.5e-11 42.4 21.3 1.5 1 1 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 TMEM215 PF15746.5 PVD38509.1 - 0.013 15.0 3.1 0.017 14.6 3.1 1.1 1 0 0 1 1 1 0 TMEM215 family PI-PLC-Y PF00387.19 PVD38509.1 - 0.16 12.4 2.6 0.36 11.2 0.9 2.1 1 1 1 2 2 2 0 Phosphatidylinositol-specific phospholipase C, Y domain YflT PF11181.8 PVD38509.1 - 1.3 9.5 5.6 2.8 8.5 0.3 2.1 1 1 1 2 2 2 0 Heat induced stress protein YflT DUF728 PF05304.12 PVD38509.1 - 1.7 8.5 6.3 0.64 9.9 3.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF728) F-112 PF09645.10 PVD38509.1 - 7.2 6.8 10.2 2.1 8.5 3.4 2.2 1 1 1 2 2 2 0 F-112 protein EMP24_GP25L PF01105.24 PVD38510.1 - 0.0046 16.9 5.4 0.0046 16.9 5.4 3.4 4 0 0 4 4 4 1 emp24/gp25L/p24 family/GOLD DUF2974 PF11187.8 PVD38511.1 - 0.22 11.0 0.6 0.4 10.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CAP_GLY PF01302.25 PVD38512.1 - 4.8e-17 61.7 0.1 8.8e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain RseC_MucC PF04246.12 PVD38512.1 - 0.72 9.8 2.7 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC bZIP_1 PF00170.21 PVD38512.1 - 6.9 6.9 7.2 31 4.8 1.0 2.9 2 1 1 3 3 3 0 bZIP transcription factor Pkinase PF00069.25 PVD38513.1 - 4.8e-68 229.4 0.0 7.5e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38513.1 - 1.8e-38 132.3 0.0 3.2e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 PVD38513.1 - 8.4e-26 90.3 0.1 1.5e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 PVD38513.1 - 9.9e-16 57.4 4.4 1.9e-15 56.4 4.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 PVD38513.1 - 0.005 17.5 0.1 0.013 16.2 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 PVD38513.1 - 0.026 14.2 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PVD38513.1 - 0.041 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PVD38513.1 - 0.044 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.16 PVD38513.1 - 0.067 13.5 6.6 0.15 12.4 6.6 1.6 1 0 0 1 1 1 0 C1 domain Haspin_kinase PF12330.8 PVD38513.1 - 0.098 11.6 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PHD_2 PF13831.6 PVD38513.1 - 0.76 9.4 5.8 0.096 12.3 0.9 2.0 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 PVD38513.1 - 1.3 9.1 3.7 3 7.9 3.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon PHD PF00628.29 PVD38513.1 - 1.5 8.7 6.8 3.6 7.6 6.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 PVD38513.1 - 2.7 8.4 6.1 1.1 9.7 2.9 2.0 1 1 1 2 2 2 0 RING-like domain Ank_2 PF12796.7 PVD38514.1 - 1.6e-23 83.1 0.0 2.7e-12 47.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38514.1 - 4.9e-22 78.0 0.1 5.8e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) PLAT PF01477.23 PVD38514.1 - 3.9e-20 72.6 2.3 5.1e-20 72.2 0.2 2.3 3 0 0 3 3 3 1 PLAT/LH2 domain Ank PF00023.30 PVD38514.1 - 6.9e-18 64.2 2.2 3.8e-07 30.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PVD38514.1 - 7.1e-17 61.3 0.1 1.4e-08 34.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38514.1 - 1.1e-16 59.2 0.2 7e-05 22.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat SAS4 PF15460.6 PVD38514.1 - 0.98 9.6 9.3 0.75 9.9 1.0 4.6 5 0 0 5 5 5 0 Something about silencing, SAS, complex subunit 4 TMC PF07810.13 PVD38515.1 - 4.6e-39 133.4 1.7 1.1e-38 132.2 1.7 1.7 1 0 0 1 1 1 1 TMC domain Solute_trans_a PF03619.16 PVD38515.1 - 0.034 13.7 7.2 0.064 12.8 7.2 1.4 1 0 0 1 1 1 0 Organic solute transporter Ostalpha Band_7 PF01145.25 PVD38516.1 - 2e-06 27.9 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Beach PF02138.18 PVD38517.1 - 1.3e-125 418.3 0.7 2.1e-125 417.7 0.7 1.3 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 PVD38517.1 - 7.3e-18 64.5 11.0 7.3e-18 64.5 11.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 PVD38517.1 - 3.4e-13 49.8 3.2 3.8e-06 27.5 0.0 6.1 6 0 0 6 6 5 2 WD domain, G-beta repeat PH_BEACH PF14844.6 PVD38517.1 - 1.5e-11 44.2 0.0 5.8e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 PVD38517.1 - 1.4e-07 31.0 1.5 1.4e-07 31.0 1.5 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 PVD38517.1 - 0.0031 17.7 0.0 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 PVD38517.1 - 0.015 14.5 0.5 0.036 13.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) IBR PF01485.21 PVD38517.1 - 0.32 11.2 5.4 1 9.7 5.4 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PVD38517.1 - 1.2 9.5 9.8 3.8 7.9 9.8 1.9 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 PVD38517.1 - 1.3 9.2 6.0 3.5 7.9 6.0 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Zf_RING PF16744.5 PVD38517.1 - 9.8 6.4 6.8 5.7 7.1 4.0 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger CHGN PF05679.16 PVD38518.1 - 2.3e-54 185.1 0.4 3.5e-48 164.7 0.1 2.6 2 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 PVD38518.1 - 2e-09 37.0 1.0 5.1e-09 35.7 1.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Tup_N PF08581.10 PVD38518.1 - 0.041 14.2 4.4 0.092 13.1 4.4 1.5 1 0 0 1 1 1 0 Tup N-terminal Jas PF16135.5 PVD38519.1 - 0.0088 16.2 0.2 0.016 15.4 0.2 1.4 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling TCR PF03638.15 PVD38520.1 - 4.1e-17 62.2 46.1 3.9e-12 46.3 24.1 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 PVD38520.1 - 0.0045 17.1 37.2 0.099 12.8 10.3 2.5 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 PfkB PF00294.24 PVD38521.1 - 3.1e-63 213.9 0.0 7.1e-63 212.7 0.0 1.5 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PCI PF01399.27 PVD38521.1 - 5.1e-17 62.3 0.2 2.3e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 PVD38521.1 - 0.0014 18.4 2.0 0.003 17.3 2.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 PVD38521.1 - 0.1 12.6 2.5 0.67 10.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PVD38521.1 - 0.19 12.3 2.5 1.7 9.2 0.0 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PVD38521.1 - 1.7 9.0 7.3 2 8.8 3.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PVD38521.1 - 3.1 8.8 5.9 8.3 7.5 0.6 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 PVD38522.1 - 1.8e-79 265.6 0.1 4.4e-79 264.3 0.1 1.7 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PVD38522.1 - 4.4e-23 80.6 5.8 6.4e-22 76.9 5.6 2.8 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 PVD38522.1 - 1.4e-20 72.9 23.7 6e-12 45.3 7.6 3.2 2 1 1 3 3 3 2 PHD-finger Linker_histone PF00538.19 PVD38522.1 - 3.4e-08 33.7 0.2 3.4e-08 33.7 0.2 3.9 4 0 0 4 4 4 1 linker histone H1 and H5 family Acetyltransf_7 PF13508.7 PVD38522.1 - 0.00097 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Prok-RING_1 PF14446.6 PVD38522.1 - 0.035 14.0 15.5 0.32 11.0 0.5 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 PVD38522.1 - 0.13 11.9 13.6 0.45 10.1 1.6 3.2 3 0 0 3 3 3 0 PHD-finger Acetyltransf_1 PF00583.25 PVD38522.1 - 0.2 11.9 0.0 0.55 10.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C4_ClpX PF06689.13 PVD38522.1 - 0.51 10.3 9.1 1 9.3 3.7 3.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger PHD_4 PF16866.5 PVD38522.1 - 3.1 8.0 18.8 0.064 13.4 7.2 3.3 1 1 1 2 2 2 0 PHD-finger AhpC-TSA_2 PF13911.6 PVD38523.1 - 1.5e-13 50.9 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PVD38523.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PVD38523.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin BolA PF01722.18 PVD38524.1 - 6.6e-18 64.8 0.4 1.6e-17 63.5 0.4 1.6 1 1 0 1 1 1 1 BolA-like protein ubiquitin PF00240.23 PVD38525.1 - 7.7e-18 64.0 0.0 1.8e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 PVD38525.1 - 1.8e-09 37.6 9.4 3.5e-09 36.7 9.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 PVD38525.1 - 0.00011 22.6 0.1 0.00041 20.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PVD38525.1 - 0.0022 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FAM220 PF15487.6 PVD38525.1 - 0.015 14.9 2.2 0.03 14.0 2.2 1.4 1 0 0 1 1 1 0 FAM220 family Allexi_40kDa PF05549.11 PVD38525.1 - 0.047 13.2 0.4 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Na_H_Exchanger PF00999.21 PVD38526.1 - 8.1e-26 90.7 25.1 8.1e-26 90.7 25.1 1.9 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family DUF1435 PF07256.12 PVD38526.1 - 0.02 15.0 0.7 0.086 13.0 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) MtrG PF04210.13 PVD38526.1 - 0.61 10.0 3.5 0.65 9.9 0.5 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Na_H_Exchanger PF00999.21 PVD38527.1 - 1.6e-17 63.4 27.4 1.6e-17 63.4 27.4 1.9 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family YlzJ PF14035.6 PVD38528.1 - 0.0027 17.9 0.9 0.013 15.7 0.2 2.3 2 0 0 2 2 2 1 YlzJ-like protein CAML PF14963.6 PVD38528.1 - 0.31 11.1 9.8 0.47 10.5 9.8 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand ALMT PF11744.8 PVD38528.1 - 6 5.6 12.8 7.9 5.2 12.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Oxidored-like PF09791.9 PVD38529.1 - 3.1e-13 49.1 3.4 7.1e-13 48.0 3.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF3409 PF11889.8 PVD38529.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) IQ PF00612.27 PVD38530.1 - 4.6e-06 25.9 0.1 1.4e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif SSF PF00474.17 PVD38531.1 - 1.9e-23 83.0 26.8 6.3e-23 81.3 26.8 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family Ras PF00071.22 PVD38532.1 - 5e-28 97.7 0.0 7.4e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD38532.1 - 2.2e-05 24.7 0.0 4.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GST_N_2 PF13409.6 PVD38534.1 - 8.3e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PVD38534.1 - 2.8e-06 27.6 0.1 1.1e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PVD38534.1 - 0.0038 17.5 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PP-binding PF00550.25 PVD38535.1 - 5.2e-11 42.7 0.2 7.7e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site FlaC_arch PF05377.11 PVD38535.1 - 0.00016 22.0 0.3 0.8 10.1 0.0 2.3 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) Amino_oxidase PF01593.24 PVD38536.1 - 5.7e-102 342.3 0.0 2.3e-59 201.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PVD38536.1 - 1.2e-11 44.6 0.4 1.3e-10 41.3 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD38536.1 - 1.1e-08 35.0 0.0 8.3e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PVD38536.1 - 1.1e-06 28.0 0.0 3.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PVD38536.1 - 0.00014 21.0 0.8 0.00026 20.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 PVD38536.1 - 0.00068 18.8 0.8 0.011 14.8 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 PVD38536.1 - 0.0011 17.7 1.2 0.012 14.4 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 PVD38536.1 - 0.0023 17.2 2.6 0.026 13.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 PVD38536.1 - 0.008 14.8 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 PVD38536.1 - 0.011 15.7 5.9 0.05 13.6 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PVD38536.1 - 0.027 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 PVD38536.1 - 0.098 11.7 0.1 0.56 9.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PVD38536.1 - 0.29 10.3 3.1 3.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Reticulon PF02453.17 PVD38537.1 - 0.0011 19.0 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Reticulon CPBP PF02517.16 PVD38537.1 - 0.39 11.1 3.0 0.3 11.5 0.6 1.8 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease UQ_con PF00179.26 PVD38538.1 - 1.8e-37 128.1 0.0 2.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PVD38538.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.22 PVD38539.1 - 1.6e-17 63.1 0.0 2.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD38539.1 - 0.0047 17.0 0.0 0.0047 17.0 0.0 2.2 2 0 0 2 2 1 1 RNA binding motif RRM_7 PF16367.5 PVD38539.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 PVD38539.1 - 0.037 13.9 0.0 0.089 12.7 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Macoilin PF09726.9 PVD38539.1 - 0.051 12.1 21.0 0.059 11.9 21.0 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 PVD38539.1 - 0.067 11.0 18.0 0.082 10.7 18.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nup35_RRM_2 PF14605.6 PVD38539.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RAP1 PF07218.11 PVD38539.1 - 0.58 8.4 19.4 0.79 7.9 19.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Presenilin PF01080.17 PVD38539.1 - 3.4 6.3 14.9 4.5 5.9 14.9 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 PVD38539.1 - 6.5 5.5 30.3 0.03 13.2 21.7 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Raftlin PF15250.6 PVD38539.1 - 7 5.3 10.8 8.6 5.0 10.8 1.2 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 PVD38539.1 - 9.1 5.2 16.0 12 4.9 16.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM86 PF14904.6 PVD38540.1 - 2.4e-21 75.6 1.7 7.8e-21 74.0 1.0 2.1 2 0 0 2 2 2 1 Family of unknown function Methyltransf_16 PF10294.9 PVD38540.1 - 1.2e-20 74.0 1.5 1.8e-10 40.8 0.2 2.5 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 PVD38540.1 - 0.00047 19.7 0.0 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PVD38540.1 - 0.054 14.2 0.3 6.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 PVD38540.1 - 0.13 13.0 0.0 2 9.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain RGS_DHEX PF18148.1 PVD38541.1 - 7e-44 148.0 1.6 2.3e-43 146.4 0.9 2.2 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 PVD38541.1 - 1.4e-33 115.6 0.8 1.4e-33 115.6 0.8 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 PVD38541.1 - 3.7e-15 55.7 0.0 8.4e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 PVD38541.1 - 2.4e-07 30.7 0.1 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 GGL domain RRM_1 PF00076.22 PVD38542.1 - 2.4e-12 46.5 0.0 3.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 PVD38542.1 - 1.1e-08 35.4 9.8 1.1e-08 35.4 9.8 4.6 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 FYTT PF07078.11 PVD38542.1 - 0.0019 17.6 0.0 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Forty-two-three protein Nucleocapsid-N PF11030.8 PVD38542.1 - 0.49 10.3 4.1 1 9.3 4.1 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N Zip PF02535.22 PVD38543.1 - 7.5 5.7 9.4 19 4.3 9.4 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter RINT1_TIP1 PF04437.13 PVD38545.1 - 1e-119 400.7 1.6 1e-119 400.7 1.6 2.4 2 1 0 2 2 2 1 RINT-1 / TIP-1 family FH2 PF02181.23 PVD38545.1 - 0.014 14.5 5.0 0.029 13.5 5.0 1.5 1 0 0 1 1 1 0 Formin Homology 2 Domain Lant_dehydr_N PF04738.13 PVD38545.1 - 0.015 13.4 0.4 0.024 12.8 0.4 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus APG6_N PF17675.1 PVD38545.1 - 0.035 14.6 5.8 0.098 13.2 5.8 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Lipoprotein_20 PF13942.6 PVD38545.1 - 0.12 12.3 2.6 0.25 11.3 2.6 1.5 1 0 0 1 1 1 0 YfhG lipoprotein ApoLp-III PF07464.11 PVD38545.1 - 0.15 12.2 7.9 1.9 8.6 6.4 2.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 PVD38545.1 - 0.2 12.1 7.3 4.7 7.8 0.3 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 PVD38545.1 - 0.22 11.5 9.8 0.78 9.8 9.8 2.0 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 PVD38545.1 - 0.23 11.7 5.2 19 5.6 5.3 2.9 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.6 PVD38545.1 - 0.28 11.4 5.3 0.76 10.0 5.3 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Apolipoprotein PF01442.18 PVD38545.1 - 0.28 11.0 7.3 1.2 9.0 7.0 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1216 PF06746.11 PVD38545.1 - 0.33 10.9 3.5 0.57 10.2 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) Syntaxin_2 PF14523.6 PVD38545.1 - 0.57 10.6 9.3 3 8.3 6.5 2.9 2 1 0 2 2 1 0 Syntaxin-like protein DUF1664 PF07889.12 PVD38545.1 - 0.71 9.9 4.8 2.2 8.4 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 PVD38545.1 - 0.73 10.2 6.1 3.4 8.1 6.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) GAS PF13851.6 PVD38545.1 - 0.75 9.1 11.5 0.83 9.0 3.4 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 PVD38545.1 - 0.91 9.7 5.8 2.5 8.3 5.8 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 PVD38545.1 - 2 8.5 10.3 12 5.9 8.2 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein JIP_LZII PF16471.5 PVD38545.1 - 4.7 7.5 8.3 23 5.2 1.6 3.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II COG2 PF06148.11 PVD38545.1 - 6.5 6.8 7.9 2.2 8.4 1.9 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.22 PVD38545.1 - 6.7 7.0 8.4 25 5.1 5.7 3.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 PVD38545.1 - 7 7.2 8.9 1.3 9.5 2.6 3.0 3 0 0 3 3 2 0 Cell division protein ZapB UQ_con PF00179.26 PVD38546.1 - 3.2e-42 143.5 0.0 4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PVD38546.1 - 6.3e-05 22.7 0.0 8.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-C2H2 PF00096.26 PVD38547.1 - 1.6e-20 72.3 64.2 0.00019 21.7 0.7 10.3 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD38547.1 - 1.3e-19 69.2 62.1 0.0007 20.2 0.6 10.0 9 1 1 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD38547.1 - 2.6e-16 59.2 51.9 1.4e-05 25.3 1.4 9.0 9 0 0 9 9 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PVD38547.1 - 4.2e-12 46.0 30.6 0.0093 16.2 0.1 8.9 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PVD38547.1 - 1.3e-08 34.9 40.9 0.0026 18.1 0.2 8.6 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PVD38547.1 - 1.6e-05 25.2 41.3 0.37 11.2 0.6 8.8 4 2 4 8 8 8 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 PVD38547.1 - 0.00072 19.5 0.2 0.00072 19.5 0.2 9.3 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PVD38547.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 6.6 8 0 0 8 8 7 2 zinc-finger C2H2-type Apc15p PF05841.11 PVD38547.1 - 0.0015 19.3 0.7 0.0044 17.8 0.7 1.7 1 0 0 1 1 1 1 Apc15p protein zf-Di19 PF05605.12 PVD38547.1 - 0.0021 18.3 3.1 0.0021 18.3 3.1 5.6 3 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 PVD38547.1 - 0.43 10.5 0.1 0.43 10.5 0.1 7.6 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 PVD38547.1 - 0.62 10.4 20.6 0.14 12.5 1.1 4.2 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 PVD38547.1 - 3.8 7.4 14.8 4.5 7.2 0.1 5.6 4 1 2 6 6 5 0 C2H2 type zinc-finger (1 copy) RAWUL PF16207.5 PVD38548.1 - 7.4e-26 90.6 0.1 1.3e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 PVD38548.1 - 8.9e-16 57.5 10.9 1.4e-15 56.8 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD38548.1 - 7.9e-10 38.4 10.7 1.3e-09 37.8 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD38548.1 - 3.8e-09 36.7 9.1 6e-09 36.1 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD38548.1 - 8.6e-08 31.9 8.1 1.2e-07 31.4 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD38548.1 - 8.7e-06 25.6 8.9 1.4e-05 24.9 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PVD38548.1 - 1e-05 25.5 8.8 1.9e-05 24.6 8.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PVD38548.1 - 8.9e-05 22.6 8.2 0.00015 21.8 8.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 PVD38548.1 - 0.00023 20.9 5.6 0.00041 20.1 5.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 PVD38548.1 - 0.00039 20.2 7.0 0.00081 19.1 7.0 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PVD38548.1 - 0.0021 18.3 7.6 0.0057 16.9 7.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 PVD38548.1 - 0.0033 17.3 3.8 0.0055 16.6 3.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-UDP PF14569.6 PVD38548.1 - 0.018 15.2 2.1 0.045 13.9 2.1 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF3337 PF11816.8 PVD38548.1 - 0.068 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Prok-RING_4 PF14447.6 PVD38548.1 - 0.074 12.9 8.9 1.2 9.1 9.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 PVD38548.1 - 0.078 12.9 7.6 0.28 11.1 7.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PVD38548.1 - 0.66 9.8 5.0 1.7 8.5 5.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 PVD38548.1 - 1.3 9.2 7.3 2.2 8.4 7.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C4_Topoisom PF01396.19 PVD38548.1 - 1.3 8.8 4.3 0.28 11.0 0.9 1.6 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger zf-MIZ PF02891.20 PVD38548.1 - 1.5 8.6 7.6 2.9 7.7 7.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger cNMP_binding PF00027.29 PVD38549.1 - 1.1e-10 41.4 0.5 0.00064 19.7 0.1 3.1 1 1 2 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 PVD38550.1 - 0.0023 18.0 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.22 PVD38551.1 - 9.4e-36 122.8 0.0 1.3e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD38551.1 - 2.5e-12 47.1 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD38551.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD38551.1 - 0.00028 20.5 0.0 0.011 15.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD38551.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD38551.1 - 0.014 14.9 0.0 0.15 11.6 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PVD38551.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 PVD38551.1 - 0.042 13.2 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein SpoU_methylase PF00588.19 PVD38553.1 - 8.1e-12 45.5 0.0 1.1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 PVD38553.1 - 3.2e-06 27.3 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding AAA_14 PF13173.6 PVD38553.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.7 PVD38554.1 - 0.00061 20.1 0.9 0.00061 20.1 0.9 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD38554.1 - 0.0013 18.2 0.7 0.026 14.0 0.2 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PVD38554.1 - 0.0028 17.4 5.7 0.034 13.9 1.5 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_2 PF07723.13 PVD38554.1 - 0.12 13.1 0.7 0.46 11.2 0.0 2.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 PVD38554.1 - 0.88 9.8 5.6 4.9 7.5 0.3 2.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PVD38554.1 - 0.91 10.3 2.8 65 4.7 0.1 3.3 2 1 0 2 2 2 0 Leucine Rich Repeat Linker_histone PF00538.19 PVD38555.1 - 8.3e-38 128.6 0.2 2.2e-13 50.4 0.1 4.7 4 0 0 4 4 4 3 linker histone H1 and H5 family 7tm_1 PF00001.21 PVD38556.1 - 1.4e-32 113.1 22.9 1.7e-32 112.8 22.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38556.1 - 2e-08 33.9 19.4 2.5e-08 33.6 19.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD38556.1 - 0.017 14.7 19.2 0.027 14.1 19.2 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 PVD38557.1 - 2e-23 83.1 6.8 2e-23 83.1 6.8 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD38557.1 - 1.3e-05 25.0 6.2 1.4e-05 24.8 6.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 PVD38557.1 - 9.8e-05 21.9 3.8 0.00012 21.5 3.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 PVD38557.1 - 0.00013 21.5 3.2 0.00013 21.5 3.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 PVD38557.1 - 0.00021 21.1 3.9 0.00027 20.8 3.9 1.1 1 0 0 1 1 1 1 Olfactory receptor PP2C PF00481.21 PVD38558.1 - 5.3e-49 167.2 0.0 8.3e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PVD38558.1 - 0.00046 19.9 0.0 0.0014 18.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 PVD38559.1 - 1.8e-64 214.3 18.8 5.4e-14 52.6 0.0 9.0 6 3 3 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD38559.1 - 1.1e-55 179.0 8.9 0.00021 21.4 0.1 13.9 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.6 PVD38559.1 - 4.1e-49 164.3 9.7 7.8e-09 35.9 0.0 10.3 8 2 3 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 PVD38559.1 - 2.1e-43 144.9 22.0 0.00037 20.8 0.0 12.5 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 PVD38559.1 - 7.6e-41 137.6 20.0 6.7e-05 23.1 0.2 11.7 8 4 4 12 12 12 11 Ankyrin repeats (many copies) Pneumo_ncap PF03246.13 PVD38559.1 - 0.14 10.9 0.7 5.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Pneumovirus nucleocapsid protein NUDIX_5 PF16705.5 PVD38560.1 - 2.8e-33 115.1 0.0 1.1e-32 113.2 0.0 2.1 2 0 0 2 2 2 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Ank_5 PF13857.6 PVD38560.1 - 7.3e-20 70.8 0.2 3.5e-10 39.9 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) FERM_M PF00373.18 PVD38560.1 - 5.7e-15 55.8 0.0 1.5e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Ank_2 PF12796.7 PVD38560.1 - 1.9e-13 50.8 0.0 1.2e-08 35.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD38560.1 - 4.6e-12 45.8 0.4 0.00037 20.8 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PVD38560.1 - 8.2e-11 42.2 0.0 3.8e-07 30.5 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38560.1 - 4.8e-07 29.6 0.6 0.19 12.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat MutS_V PF00488.21 PVD38561.1 - 1.6e-67 227.2 0.1 2.8e-67 226.4 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PVD38561.1 - 3.1e-30 105.8 0.1 3.1e-30 105.8 0.1 2.0 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 PVD38561.1 - 2e-10 41.1 0.0 5.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 PVD38561.1 - 1.7e-07 31.5 0.0 4.9e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 PVD38561.1 - 0.0059 16.6 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PVD38561.1 - 0.055 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 PVD38561.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PVD38561.1 - 0.16 12.4 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain UNC-93 PF05978.16 PVD38562.1 - 2.8e-07 30.4 6.2 2.8e-07 30.4 6.2 3.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3742 PF12553.8 PVD38562.1 - 1.6 8.9 3.8 4.2 7.5 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Ndc1_Nup PF09531.10 PVD38562.1 - 6.3 5.3 12.4 10 4.7 12.1 1.6 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup 7tm_1 PF00001.21 PVD38563.1 - 3.2e-53 180.7 16.7 4.3e-53 180.3 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38563.1 - 2e-09 37.3 10.1 5.2e-09 35.9 10.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD38563.1 - 1.8e-06 27.9 7.9 3.9e-06 26.8 7.9 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 PVD38563.1 - 4.4e-06 26.5 12.1 8.9e-06 25.5 12.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2418 PF10332.9 PVD38563.1 - 3.8 8.1 7.1 2.6 8.6 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2418) 7tm_1 PF00001.21 PVD38564.1 - 6.9e-28 97.7 15.5 2.1e-27 96.1 15.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD38564.1 - 9.6e-05 22.1 5.9 0.00086 19.0 5.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD38564.1 - 0.00065 19.1 7.0 0.017 14.5 7.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2070 PF09843.9 PVD38564.1 - 0.47 8.7 4.9 0.65 8.2 4.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_5 PF13346.6 PVD38564.1 - 5.4 6.5 10.8 9.8 5.7 10.8 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Phage_holin_3_6 PF07332.11 PVD38565.1 - 1.2 9.2 7.6 1.2 9.1 1.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SPC12 PF06645.13 PVD38565.1 - 9.3 6.4 7.3 15 5.7 0.4 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Claudin_2 PF13903.6 PVD38566.1 - 7.1e-05 22.6 4.3 0.016 14.9 0.1 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD38566.1 - 0.29 11.0 6.2 0.17 11.7 1.8 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family KTI12 PF08433.10 PVD38567.1 - 1.5e-76 257.4 0.0 1.7e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PVD38567.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 PVD38568.1 - 5.6e-13 49.2 17.3 0.00011 22.7 1.5 7.7 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 PVD38568.1 - 1.9e-12 46.3 23.7 0.0022 18.0 0.1 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 PVD38568.1 - 7.2e-11 42.2 12.8 0.12 12.6 0.1 7.9 6 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD38568.1 - 2.3e-09 37.4 21.7 1.3e-05 25.3 6.9 5.6 5 1 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PVD38568.1 - 8.7e-09 34.8 20.9 0.0068 16.2 0.2 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD38568.1 - 4.5e-07 29.4 9.3 0.53 10.4 0.2 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD38568.1 - 2.5e-05 24.8 0.6 3.8 8.2 0.3 5.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD38568.1 - 6.1e-05 23.5 8.4 0.077 13.8 0.1 6.8 6 3 4 10 10 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PVD38568.1 - 0.0001 22.2 22.2 0.16 12.2 0.0 8.1 10 0 0 10 10 8 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PVD38568.1 - 0.0029 17.6 22.9 0.16 12.0 0.8 6.1 4 2 3 7 7 7 1 Putative TPR-like repeat HrpB1_HrpK PF09613.10 PVD38568.1 - 0.0036 17.0 4.1 0.077 12.6 0.1 4.4 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 PVD38568.1 - 0.0093 16.0 11.7 3 8.0 0.1 5.5 5 1 1 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 PVD38568.1 - 0.011 16.3 16.8 0.21 12.3 0.1 6.8 7 1 0 7 7 6 0 Tetratricopeptide repeat DUF285 PF03382.14 PVD38568.1 - 0.02 14.7 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 LMBR1 PF04791.16 PVD38568.1 - 0.02 13.8 0.8 0.029 13.3 0.1 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein BEX PF04538.12 PVD38568.1 - 0.045 14.4 1.9 0.07 13.7 0.1 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family SMBP PF16785.5 PVD38568.1 - 0.058 13.6 0.7 4.6 7.5 0.1 3.2 3 0 0 3 3 3 0 Small metal-binding protein DUF2205 PF10224.9 PVD38568.1 - 0.086 12.8 0.5 0.32 11.0 0.5 2.0 1 0 0 1 1 1 0 Short coiled-coil protein PPR_2 PF13041.6 PVD38568.1 - 0.17 12.1 2.6 48 4.2 0.0 5.1 5 1 0 5 5 5 0 PPR repeat family DUF2054 PF10218.9 PVD38568.1 - 0.23 11.6 3.1 0.37 10.9 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) TPR_9 PF13371.6 PVD38568.1 - 0.33 11.1 2.4 13 6.0 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN6_N PF18055.1 PVD38568.1 - 5.6 7.3 8.5 19 5.7 0.7 4.0 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain COQ7 PF03232.13 PVD38568.1 - 6.7 6.5 7.0 23 4.7 0.0 2.9 3 0 0 3 3 2 0 Ubiquinone biosynthesis protein COQ7 SlyX PF04102.12 PVD38568.1 - 7.3 7.3 10.6 4.6 7.9 1.2 4.1 4 0 0 4 4 4 0 SlyX Noggin PF05806.12 PVD38569.1 - 1.9e-63 214.2 5.8 2.4e-63 214.0 5.8 1.0 1 0 0 1 1 1 1 Noggin Noggin PF05806.12 PVD38572.1 - 1.3e-21 77.5 6.4 9.1e-15 55.2 0.2 2.2 1 1 1 2 2 2 2 Noggin Serglycin PF04360.12 PVD38572.1 - 0.035 14.0 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Serglycin BatD PF13584.6 PVD38576.1 - 0.0073 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance DUF5134 PF17197.4 PVD38576.1 - 0.034 14.1 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) U3_assoc_6 PF08640.11 PVD38577.1 - 5e-23 81.0 11.9 8.3e-23 80.3 11.9 1.4 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 UPF0489 PF12640.7 PVD38579.1 - 5.3e-19 69.1 5.4 3.7e-14 53.3 0.6 3.4 2 2 0 2 2 2 2 UPF0489 domain SPATIAL PF15256.6 PVD38580.1 - 4.4e-60 203.4 0.0 3.9e-59 200.4 0.0 2.0 2 0 0 2 2 2 1 SPATIAL tRNA_m1G_MT PF01746.21 PVD38581.1 - 1.5e-30 106.3 0.1 2.3e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF3294 PF07957.11 PVD38581.1 - 0.0055 16.5 0.2 1.1 9.0 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3294) hNIFK_binding PF12196.8 PVD38581.1 - 0.091 12.3 2.3 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Vitellogenin_N PF01347.22 PVD38582.1 - 6.9e-32 110.6 1.3 8.4e-27 93.8 0.7 2.1 1 1 0 2 2 2 2 Lipoprotein amino terminal region HEAT_2 PF13646.6 PVD38582.1 - 0.0028 18.0 0.0 0.4 11.1 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats zf-3CxxC_2 PF17180.4 PVD38583.1 - 7.1e-27 93.9 8.9 7.1e-27 93.9 8.9 1.9 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 PVD38583.1 - 3e-11 42.9 3.4 3e-11 42.9 3.4 3.4 5 0 0 5 5 5 1 Zinc knuckle UPF0515 PF15135.6 PVD38583.1 - 0.0012 18.3 8.7 0.0016 17.8 8.7 1.4 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 PVD38583.1 - 0.0083 16.6 16.8 0.06 13.8 14.2 2.9 2 1 0 2 2 2 1 Zinc-binding domain zf-CCHC PF00098.23 PVD38583.1 - 0.12 12.6 1.5 0.12 12.6 1.5 3.1 4 0 0 4 4 4 0 Zinc knuckle zf-Dof PF02701.15 PVD38583.1 - 0.57 10.4 11.8 11 6.2 4.6 3.6 3 0 0 3 3 3 0 Dof domain, zinc finger zf-CHY PF05495.12 PVD38583.1 - 0.71 10.4 13.4 1.3 9.5 2.1 2.5 2 1 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 PVD38583.1 - 2.1 8.8 9.3 0.46 11.0 4.8 2.0 1 1 1 2 2 2 0 Cytochrome c3 LigB PF02900.18 PVD38584.1 - 3.2e-31 108.4 0.0 4.4e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase RHD_DNA_bind PF00554.22 PVD38585.1 - 1.2e-57 194.5 0.2 2.7e-57 193.4 0.2 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 PVD38585.1 - 2.3e-37 127.1 0.1 4.3e-37 126.3 0.1 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 PVD38585.1 - 2.9e-30 104.7 1.8 2.6e-12 47.2 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38585.1 - 1.2e-28 99.0 1.6 1.3e-07 32.0 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PVD38585.1 - 6e-25 86.5 15.1 2.5e-05 24.5 0.2 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PVD38585.1 - 3.4e-24 82.3 8.9 0.011 16.1 0.1 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 PVD38585.1 - 2.8e-19 68.9 15.0 1.8e-06 28.1 0.6 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Death PF00531.22 PVD38585.1 - 4.3e-05 23.6 0.0 9.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Death domain GRP PF07172.11 PVD38585.1 - 0.53 11.0 22.1 0.53 11.0 20.2 2.0 2 0 0 2 2 2 0 Glycine rich protein family PARG_cat PF05028.14 PVD38586.1 - 1.8e-128 428.6 0.0 2.5e-128 428.1 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.13 PVD38586.1 - 0.065 11.5 0.0 0.09 11.0 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) PARG_cat PF05028.14 PVD38587.1 - 2.8e-120 401.6 0.1 4.1e-120 401.1 0.1 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.13 PVD38587.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Ribosomal_S24e PF01282.19 PVD38588.1 - 1.1e-37 127.8 0.6 2.9e-37 126.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S24e PBECR1 PF18809.1 PVD38588.1 - 0.009 16.7 0.1 0.013 16.2 0.1 1.2 1 0 0 1 1 1 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Mito_carr PF00153.27 PVD38589.1 - 5.6e-41 138.4 0.3 3.7e-21 74.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein SH3_1 PF00018.28 PVD38590.1 - 6.4e-32 108.9 1.6 3.8e-15 55.2 0.1 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 PVD38590.1 - 1.9e-29 101.3 0.2 7.7e-15 54.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 PVD38590.1 - 6.1e-21 74.3 0.2 1.6e-20 73.0 0.2 1.7 1 1 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 PVD38590.1 - 3.8e-20 71.3 0.0 2.6e-09 36.6 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain MazE_antitoxin PF04014.18 PVD38590.1 - 0.012 15.5 0.2 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin MbtH PF03621.13 PVD38590.1 - 0.025 14.0 0.1 0.077 12.5 0.1 1.8 1 1 0 1 1 1 0 MbtH-like protein SH3_3 PF08239.11 PVD38590.1 - 0.031 14.6 0.4 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 PVD38590.1 - 0.036 14.1 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 SH3 domain DUF3850 PF12961.7 PVD38590.1 - 0.038 14.0 0.1 4 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) DUF4648 PF15505.6 PVD38590.1 - 0.12 13.2 0.0 0.64 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) SRP68 PF16969.5 PVD38591.1 - 2.2e-138 462.7 2.6 2.2e-138 462.7 2.6 2.1 1 1 1 2 2 2 1 RNA-binding signal recognition particle 68 TPR_7 PF13176.6 PVD38591.1 - 6e-06 25.9 2.8 0.0074 16.2 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PVD38591.1 - 2.9e-05 24.3 5.2 0.018 15.3 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD38591.1 - 3.3e-05 23.5 3.6 0.027 14.3 2.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PVD38591.1 - 4.1e-05 23.4 7.5 0.01 15.9 2.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD38591.1 - 4.3e-05 23.9 3.5 0.039 14.6 1.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PVD38591.1 - 5.8e-05 22.8 5.6 0.0013 18.6 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat BRO1 PF03097.18 PVD38591.1 - 0.0032 16.3 0.2 0.0032 16.3 0.2 2.6 3 0 0 3 3 3 1 BRO1-like domain TPR_11 PF13414.6 PVD38591.1 - 0.0088 15.7 0.7 0.32 10.7 0.6 2.5 2 0 0 2 2 2 1 TPR repeat MIT PF04212.18 PVD38591.1 - 0.029 14.4 6.5 0.06 13.4 1.3 3.7 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 PVD38591.1 - 0.032 15.0 0.9 0.59 11.1 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PVD38591.1 - 0.032 14.9 3.6 0.16 12.7 0.6 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat NfrA_C PF13283.6 PVD38591.1 - 0.037 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Recep_L_domain PF01030.24 PVD38592.1 - 5.7e-21 74.7 0.0 7.6e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Receptor L domain Furin-like PF00757.20 PVD38592.1 - 2.5e-15 56.6 19.0 4e-15 56.0 19.0 1.3 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 PVD38592.1 - 0.00019 21.3 22.4 0.00038 20.3 22.4 1.7 1 1 0 1 1 1 1 Growth factor receptor domain IV zf-C4 PF00105.18 PVD38597.1 - 9.2e-33 112.5 16.4 9.2e-33 112.5 16.4 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD38597.1 - 3.9e-13 49.4 0.0 8.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PVL_ORF50 PF07768.11 PVD38602.1 - 0.038 14.3 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family Band_7 PF01145.25 PVD38604.1 - 3.8e-26 92.2 1.5 5e-26 91.8 1.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 PVD38604.1 - 0.012 14.7 1.0 0.016 14.3 1.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Med2 PF11214.8 PVD38604.1 - 0.066 13.4 1.0 0.11 12.7 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 FliG_N PF14842.6 PVD38604.1 - 0.23 12.0 5.4 0.3 11.7 1.6 2.2 2 0 0 2 2 2 0 FliG N-terminal domain SNAPc19 PF15497.6 PVD38605.1 - 1e-12 48.3 12.2 1e-12 48.3 12.2 1.9 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF2855 PF11017.8 PVD38605.1 - 0.1 12.3 0.6 0.13 12.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) LETM1 PF07766.13 PVD38606.1 - 3.3e-37 128.3 0.2 4e-37 128.0 0.2 1.0 1 0 0 1 1 1 1 LETM1-like protein DUF816 PF05674.12 PVD38606.1 - 0.023 14.6 0.1 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF816) CSRNP_N PF16019.5 PVD38607.1 - 2.6e-90 302.1 7.4 6.6e-90 300.8 7.4 1.7 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus UBA PF00627.31 PVD38608.1 - 5.9e-18 64.4 0.0 1.9e-05 24.4 0.0 3.5 3 0 0 3 3 3 3 UBA/TS-N domain Ubiquitin_5 PF18037.1 PVD38608.1 - 2.8e-13 50.0 1.9 1e-12 48.3 1.9 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 PVD38608.1 - 5e-10 39.0 0.6 1.3e-09 37.7 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin family HOIP-UBA PF16678.5 PVD38608.1 - 4.2e-07 30.1 1.9 0.0018 18.3 0.3 3.7 2 1 1 3 3 3 2 HOIP UBA domain pair UBA_3 PF09288.10 PVD38608.1 - 0.0033 17.2 1.6 4.3 7.2 0.0 4.5 4 0 0 4 4 4 1 Fungal ubiquitin-associated domain HTH_8 PF02954.19 PVD38608.1 - 0.0053 16.5 0.3 0.81 9.5 0.0 3.4 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family DUF2407 PF10302.9 PVD38608.1 - 0.05 14.2 5.6 0.094 13.3 0.1 3.0 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain DUF4878 PF12870.7 PVD38608.1 - 0.14 12.4 9.3 0.47 10.8 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4878) PTSIIB_sorb PF03830.15 PVD38608.1 - 0.35 11.1 4.1 0.15 12.3 0.3 2.3 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component TPR_2 PF07719.17 PVD38608.1 - 4.9 7.5 10.8 4.6 7.6 0.9 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PIP5K PF01504.18 PVD38609.1 - 2e-43 148.6 1.3 1.7e-33 116.0 1.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 PVD38609.1 - 5.3e-28 97.9 0.0 9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEP PF00610.21 PVD38609.1 - 1.5e-18 66.6 0.0 3.4e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE PF01363.21 PVD38609.1 - 4.9e-16 58.6 15.4 4.9e-16 58.6 15.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger EF-hand_like PF09279.11 PVD38609.1 - 0.42 11.1 2.3 4.4 7.9 0.1 2.7 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like 7tm_1 PF00001.21 PVD38610.1 - 5.7e-53 179.9 2.7 9e-53 179.3 2.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_8 PF01501.20 PVD38610.1 - 2.4e-42 145.3 0.8 5.2e-33 114.7 0.0 3.9 2 2 1 3 3 3 2 Glycosyl transferase family 8 7TM_GPCR_Srsx PF10320.9 PVD38610.1 - 2.7e-05 23.7 13.1 0.00045 19.7 6.7 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD38610.1 - 0.00063 19.6 3.3 0.0013 18.6 3.3 1.5 1 0 0 1 1 1 1 Olfactory receptor LRR_adjacent PF08191.11 PVD38610.1 - 0.083 13.1 0.2 22 5.4 0.1 2.6 2 0 0 2 2 2 0 LRR adjacent BK_channel_a PF03493.18 PVD38610.1 - 0.13 12.4 0.0 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit 7TM_GPCR_Srx PF10328.9 PVD38610.1 - 2.9 7.4 12.2 0.32 10.6 6.3 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Glyco_transf_8 PF01501.20 PVD38611.1 - 1.2e-15 57.8 0.2 8.5e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 PVD38611.1 - 0.055 12.9 0.0 0.087 12.2 0.0 1.4 1 1 0 1 1 1 0 Glucosyltransferase 24 PRIMA1 PF16101.5 PVD38611.1 - 0.14 12.2 2.4 0.23 11.5 2.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4515 PF14988.6 PVD38613.1 - 0.014 15.3 0.2 0.028 14.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) adh_short_C2 PF13561.6 PVD38614.1 - 6.2e-48 163.4 0.0 8.5e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD38614.1 - 9.6e-41 139.4 0.2 1.4e-40 138.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PVD38614.1 - 8.6e-08 32.3 0.1 1.1e-07 31.9 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF2700 PF10912.8 PVD38615.1 - 0.065 13.3 2.7 0.23 11.5 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2700) LAP1C PF05609.12 PVD38616.1 - 4.4 6.3 28.1 2.3 7.2 26.0 1.5 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) KCT2 PF17818.1 PVD38617.1 - 2.3e-11 44.2 2.7 2.3e-11 44.2 2.7 2.0 1 1 1 2 2 2 1 Keratinocyte-associated gene product Dynein_light PF01221.18 PVD38618.1 - 1.5e-28 98.9 0.4 1.8e-28 98.7 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 PVD38618.1 - 0.0094 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) Ground-like PF04155.18 PVD38618.1 - 0.048 14.3 0.1 0.065 13.9 0.1 1.3 1 0 0 1 1 1 0 Ground-like domain Swm2 PF17083.5 PVD38618.1 - 0.074 13.1 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 eIF_4EBP PF05456.11 PVD38619.1 - 1.9e-34 118.0 0.0 2.1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HECT PF00632.25 PVD38620.1 - 1.9e-88 296.9 0.3 1.9e-88 296.9 0.3 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PVD38620.1 - 1.4e-75 249.7 24.5 5e-17 62.3 0.3 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PVD38620.1 - 3.2e-38 128.8 29.2 7.5e-08 32.0 2.0 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF2989 PF11207.8 PVD38620.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) HAP1_N PF04849.13 PVD38621.1 - 0.0021 17.3 3.7 0.0021 17.3 3.7 3.2 2 1 1 3 3 3 1 HAP1 N-terminal conserved region DMPK_coil PF08826.10 PVD38621.1 - 0.0098 16.0 5.4 0.0098 16.0 5.4 4.3 5 0 0 5 5 5 1 DMPK coiled coil domain like ERM PF00769.19 PVD38621.1 - 0.012 15.5 25.7 0.017 15.0 6.6 2.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 PVD38621.1 - 0.014 15.6 7.7 0.014 15.6 7.7 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain zf-HC2 PF13490.6 PVD38621.1 - 0.085 13.1 0.4 0.25 11.6 0.4 1.9 1 0 0 1 1 1 0 Putative zinc-finger FapA PF03961.13 PVD38621.1 - 0.41 9.2 23.1 0.12 11.0 10.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A GAS PF13851.6 PVD38621.1 - 2.5 7.4 42.7 0.074 12.4 8.7 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PLA2G12 PF06951.11 PVD38622.1 - 5.5e-17 62.3 3.7 5.7e-17 62.2 3.7 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 PVD38622.1 - 0.0035 18.0 0.6 0.0035 18.0 0.6 1.5 1 1 1 2 2 2 1 Prokaryotic phospholipase A2 FA_desaturase PF00487.24 PVD38623.1 - 7.9e-15 55.4 15.8 7.9e-15 55.4 15.8 1.9 1 1 1 2 2 2 2 Fatty acid desaturase V-SNARE_C PF12352.8 PVD38626.1 - 2.7e-20 72.4 7.2 3.1e-20 72.2 5.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PVD38626.1 - 6e-18 65.0 7.3 6e-18 65.0 7.3 1.8 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 PVD38626.1 - 0.0011 18.8 3.3 0.0018 18.2 0.2 2.3 2 1 0 2 2 2 1 Sec20 RapH_N PF18801.1 PVD38626.1 - 0.056 13.5 1.2 0.14 12.2 1.2 1.7 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Mog1 PF04603.12 PVD38626.1 - 0.24 11.8 2.2 0.43 10.9 2.2 1.4 1 0 0 1 1 1 0 Ran-interacting Mog1 protein UPF0231 PF06062.11 PVD38626.1 - 0.44 10.8 4.8 0.79 10.0 2.9 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Mt_ATP-synt_D PF05873.12 PVD38626.1 - 0.98 9.3 5.5 7.2 6.5 5.5 2.2 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Exonuc_VII_L PF02601.15 PVD38626.1 - 1.1 8.8 14.8 2.1 7.8 14.2 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit PBP_sp32 PF07222.12 PVD38626.1 - 3.4 7.1 6.8 1.6 8.1 4.5 1.6 1 1 1 2 2 2 0 Proacrosin binding protein sp32 7tm_2 PF00002.24 PVD38627.1 - 5.8e-09 35.6 6.0 1.2e-08 34.6 6.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 PVD38627.1 - 0.00077 19.8 9.1 0.0046 17.3 9.1 2.4 1 0 0 1 1 1 1 Somatomedin B domain zf-HIT PF04438.16 PVD38627.1 - 0.29 11.0 4.2 2.2 8.2 0.2 2.9 2 0 0 2 2 2 0 HIT zinc finger Pkinase PF00069.25 PVD38629.1 - 4.7e-73 245.8 0.0 6.5e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38629.1 - 1.7e-41 142.2 0.0 2.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 PVD38629.1 - 1.4e-11 43.9 0.0 3.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 PVD38629.1 - 3.8e-09 36.3 0.0 1.4e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PVD38629.1 - 1.6e-05 24.3 0.0 5.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD38629.1 - 0.0019 17.2 1.1 0.034 13.1 0.1 2.3 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PVD38629.1 - 0.0068 16.4 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PVD38629.1 - 0.019 14.5 0.1 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase IRS PF02174.17 PVD38631.1 - 5.4e-10 39.1 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DUF3306 PF11748.8 PVD38631.1 - 0.59 11.0 6.1 97 3.9 6.1 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) ANF_receptor PF01094.28 PVD38632.1 - 5e-65 219.9 0.0 7.1e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 PVD38632.1 - 8.1e-48 163.2 21.9 1.4e-47 162.5 21.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 PVD38632.1 - 6.1e-10 38.9 12.6 1.4e-09 37.8 12.6 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 PVD38632.1 - 7.5e-10 39.0 1.7 1.5e-09 38.0 1.7 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Colicin_im PF03857.13 PVD38632.1 - 0.54 10.2 7.0 4.1 7.4 0.2 2.6 2 0 0 2 2 2 0 Colicin immunity protein Sulfotransfer_2 PF03567.14 PVD38633.1 - 2.6e-29 102.9 2.9 5.1e-26 92.1 0.3 2.2 1 1 1 2 2 2 2 Sulfotransferase family Hamartin PF04388.12 PVD38634.1 - 3.1 6.3 18.4 3.6 6.1 18.4 1.0 1 0 0 1 1 1 0 Hamartin protein CD20 PF04103.15 PVD38635.1 - 5.9e-05 23.2 0.4 0.0001 22.4 0.4 1.4 1 0 0 1 1 1 1 CD20-like family FA_desaturase PF00487.24 PVD38635.1 - 0.033 14.0 3.5 0.1 12.4 3.6 1.7 1 1 0 1 1 1 0 Fatty acid desaturase TMEM100 PF16311.5 PVD38635.1 - 0.13 11.9 0.3 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 RRT14 PF17075.5 PVD38636.1 - 0.2 11.7 5.5 0.28 11.3 5.5 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 DUF2976 PF11190.8 PVD38637.1 - 0.25 11.2 1.4 0.5 10.2 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) ExoD PF06055.12 PVD38637.1 - 0.46 9.8 6.6 4 6.8 1.1 2.0 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD Peptidase_C12 PF01088.21 PVD38638.1 - 8.7e-71 238.0 0.0 2e-70 236.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PVD38638.1 - 1.6e-19 69.5 2.7 4.1e-19 68.2 2.7 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Coatomer_WDAD PF04053.14 PVD38638.1 - 2.1e-08 33.7 9.1 0.0036 16.4 0.0 4.4 3 1 1 4 4 4 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 PVD38638.1 - 3.5e-06 27.2 0.2 0.023 15.0 0.0 4.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 PVD38638.1 - 0.00021 21.8 15.3 1.8 9.6 0.0 8.5 7 1 2 9 9 8 1 Tetratricopeptide repeat Clathrin PF00637.20 PVD38638.1 - 0.0003 20.7 16.5 0.14 12.0 0.3 6.4 5 1 2 7 7 7 2 Region in Clathrin and VPS TPR_19 PF14559.6 PVD38638.1 - 0.0014 19.1 16.1 1.4 9.5 0.3 5.9 5 2 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PVD38638.1 - 0.004 17.2 27.7 0.1 12.7 2.2 9.6 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR_2 PF13041.6 PVD38638.1 - 0.044 14.0 2.7 10 6.4 0.1 5.0 4 0 0 4 4 4 0 PPR repeat family TPR_7 PF13176.6 PVD38638.1 - 0.076 13.1 23.4 6 7.1 0.0 9.0 9 2 2 11 11 9 0 Tetratricopeptide repeat PPR PF01535.20 PVD38638.1 - 0.3 11.4 13.2 8.9 6.8 0.1 7.5 7 1 1 8 8 8 0 PPR repeat TPR_1 PF00515.28 PVD38638.1 - 0.45 10.4 24.6 1.5 8.7 2.5 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD38638.1 - 0.7 10.2 22.6 3.7 7.8 2.0 8.3 8 2 2 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_1 PF12854.7 PVD38638.1 - 1 9.1 3.1 18 5.1 0.2 4.1 4 0 0 4 4 4 0 PPR repeat MIT PF04212.18 PVD38638.1 - 4.9 7.3 9.7 3.8 7.7 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Chitin_synth_2 PF03142.15 PVD38640.1 - 1.9e-28 99.4 10.8 2.6e-25 89.1 0.2 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 PVD38640.1 - 4.7e-11 43.0 4.7 4.7e-11 43.0 4.7 3.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PVD38640.1 - 1.2e-07 31.9 0.1 2.4e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PVD38640.1 - 0.013 15.3 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Guanylate_kin PF00625.21 PVD38644.1 - 6.1e-42 143.4 0.1 2.3e-41 141.5 0.1 1.9 1 1 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 PVD38644.1 - 1.1e-13 51.3 0.7 7.6e-13 48.6 0.4 2.2 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.28 PVD38644.1 - 8.5e-08 31.7 0.2 5.1e-07 29.2 0.2 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD38644.1 - 1.1e-07 31.4 0.0 3.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain L27 PF02828.16 PVD38644.1 - 1.5e-06 27.8 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 L27 domain PDZ_6 PF17820.1 PVD38644.1 - 2.9e-05 23.8 0.1 0.00011 22.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 PVD38644.1 - 0.0015 18.4 0.4 0.0034 17.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain AAA_5 PF07728.14 PVD38644.1 - 0.015 15.3 0.1 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDZ_2 PF13180.6 PVD38644.1 - 0.082 13.2 0.2 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 PDZ domain WW PF00397.26 PVD38645.1 - 3e-09 36.8 0.9 8.1e-09 35.4 0.9 1.7 1 0 0 1 1 1 1 WW domain kleA_kleC PF17383.2 PVD38645.1 - 1.2 9.5 4.2 1.1 9.6 0.8 2.6 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF1690 PF07956.11 PVD38645.1 - 7.5 7.0 9.9 0.47 10.9 3.1 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Oxysterol_BP PF01237.18 PVD38646.1 - 3.6e-133 444.0 3.6 3.6e-133 444.0 3.6 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 PVD38646.1 - 6.9e-09 35.9 0.2 2.1e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 PVD38646.1 - 5.7e-07 30.0 0.2 1.6e-06 28.6 0.2 1.8 1 0 0 1 1 1 1 PH domain Arfaptin PF06456.13 PVD38648.1 - 1.4e-56 191.7 14.4 1.2e-47 162.5 3.4 2.8 2 1 1 3 3 3 2 Arfaptin-like domain ICA69 PF04629.14 PVD38648.1 - 1.1e-37 130.7 11.4 1e-36 127.6 11.4 2.1 1 1 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain Com_YlbF PF06133.11 PVD38648.1 - 0.34 11.5 6.0 3.5 8.3 0.1 3.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF4446 PF14584.6 PVD38648.1 - 4.2 7.3 6.5 3.7 7.5 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) BAR_2 PF10455.9 PVD38648.1 - 9.1 5.3 11.3 1.1 8.3 6.3 2.1 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking GYF_2 PF14237.6 PVD38649.1 - 7.2e-18 64.1 0.7 2e-17 62.7 0.7 1.9 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 PVD38649.1 - 4.9e-14 52.2 3.2 5.6e-14 52.0 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain HEAT PF02985.22 PVD38649.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat LRR_8 PF13855.6 PVD38650.1 - 1.5e-64 213.6 77.2 4.5e-11 42.3 7.3 11.3 5 4 7 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 PVD38650.1 - 2.2e-51 170.9 88.7 1.1e-06 28.8 2.1 14.1 8 3 9 17 17 17 17 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD38650.1 - 2.2e-14 53.4 39.6 0.00032 20.2 1.3 8.0 2 2 7 9 9 9 7 Leucine-rich repeat Death PF00531.22 PVD38650.1 - 4.7e-06 26.7 2.4 1.5e-05 25.1 0.1 3.1 3 1 0 3 3 3 1 Death domain RsmF_methylt_CI PF17126.5 PVD38650.1 - 6.6e-06 26.1 2.5 2.1 8.5 0.0 7.4 6 3 2 8 8 8 1 RsmF rRNA methyltransferase first C-terminal domain LRR_5 PF13306.6 PVD38650.1 - 0.00099 19.1 4.7 0.33 10.9 0.4 3.3 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD38650.1 - 0.0016 18.7 72.1 1.6 9.6 0.5 18.6 17 4 1 18 18 18 2 Leucine Rich Repeat CSTF_C PF14304.6 PVD38650.1 - 1.2 8.7 4.3 63 3.3 0.0 4.6 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal SNF PF00209.18 PVD38651.1 - 1.3e-153 512.4 23.7 1.3e-153 512.4 23.7 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Acetyltransf_1 PF00583.25 PVD38651.1 - 0.19 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family 7tm_1 PF00001.21 PVD38653.1 - 9.3e-07 28.4 1.0 1.2e-06 28.0 1.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 PVD38654.1 - 1.7e-10 40.7 1.7 2.5e-10 40.1 1.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD38654.1 - 0.00053 19.8 2.0 0.00067 19.5 2.0 1.1 1 0 0 1 1 1 1 Olfactory receptor GAS PF13851.6 PVD38655.1 - 3.4e-05 23.3 94.1 0.002 17.5 21.8 5.3 2 2 2 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 PVD38655.1 - 0.00059 19.9 54.0 0.0021 18.1 25.7 5.8 1 1 4 5 5 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 PVD38655.1 - 0.0043 16.9 31.1 0.0043 16.9 31.1 3.5 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF641 PF04859.12 PVD38655.1 - 0.018 15.3 9.4 0.018 15.3 9.4 6.6 2 2 4 6 6 6 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.7 PVD38655.1 - 0.019 15.2 15.0 0.019 15.2 15.0 5.6 2 2 3 5 5 4 0 Tropomyosin like YabA PF06156.13 PVD38655.1 - 0.047 14.3 74.4 0.058 14.0 9.1 7.1 1 1 5 6 6 6 0 Initiation control protein YabA Spc7 PF08317.11 PVD38655.1 - 0.21 10.4 89.3 0.052 12.4 24.9 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein CENP-H PF05837.12 PVD38655.1 - 0.35 11.3 87.2 0.046 14.1 11.0 5.9 2 2 3 5 5 5 0 Centromere protein H (CENP-H) FPP PF05911.11 PVD38655.1 - 0.42 8.8 78.6 0.45 8.6 33.3 3.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 PVD38655.1 - 0.51 10.9 104.9 4.4 7.8 12.3 5.6 1 1 5 6 6 6 0 Apg6 coiled-coil region Fib_alpha PF08702.10 PVD38655.1 - 0.82 9.8 59.9 0.049 13.8 8.3 5.7 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 PVD38655.1 - 1.2 8.5 88.9 0.036 13.5 49.7 3.2 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 PVD38655.1 - 2.3 8.3 95.8 0.88 9.6 6.5 6.5 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 PVD38655.1 - 5 7.6 64.6 0.72 10.3 1.2 8.8 5 4 3 9 9 9 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 PVD38655.1 - 5.8 6.8 82.9 0.23 11.2 2.4 9.7 2 2 6 9 9 9 0 Septum formation initiator Sec20 PF03908.13 PVD38655.1 - 7.8 6.5 30.2 3.8 7.5 2.0 5.2 2 1 2 5 5 5 0 Sec20 FlxA PF14282.6 PVD38655.1 - 8.7 6.4 62.8 2.1 8.4 9.1 6.1 2 2 3 6 6 6 0 FlxA-like protein HOOK PF05622.12 PVD38655.1 - 9.1 4.3 84.3 1.9 6.5 21.8 3.6 1 1 2 3 3 3 0 HOOK protein UPF0728 PF15092.6 PVD38657.1 - 1.5e-36 124.1 0.0 1.7e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Glyco_hydro_32C PF08244.12 PVD38657.1 - 0.0092 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal RACo_linker PF17650.1 PVD38657.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RACo linker region Nfu_N PF08712.11 PVD38658.1 - 1.9e-32 111.2 0.0 5.9e-32 109.6 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 PVD38658.1 - 2.3e-27 94.9 0.0 3.8e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain LtrA PF06772.11 PVD38660.1 - 0.013 14.8 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Pox_I5 PF04713.12 PVD38660.1 - 0.043 13.9 0.4 0.097 12.7 0.4 1.6 1 0 0 1 1 1 0 Poxvirus protein I5 PIRT PF15099.6 PVD38660.1 - 0.071 12.7 0.1 0.071 12.7 0.1 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Virul_fac_BrkB PF03631.15 PVD38660.1 - 0.14 11.8 0.2 0.19 11.3 0.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF2207 PF09972.9 PVD38661.1 - 0.19 10.5 0.4 0.25 10.1 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 PVD38661.1 - 8.3 5.4 7.8 12 4.9 7.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PIRT PF15099.6 PVD38662.1 - 0.0002 20.9 0.3 0.0016 18.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family SfLAP PF11139.8 PVD38662.1 - 0.0012 18.4 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein TMEM100 PF16311.5 PVD38662.1 - 0.0058 16.2 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 100 TMEM174 PF15029.6 PVD38662.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 DUF202 PF02656.15 PVD38662.1 - 0.034 14.6 0.1 0.071 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Cation_efflux PF01545.21 PVD38662.1 - 0.038 13.7 0.1 0.64 9.7 0.0 1.9 1 1 1 2 2 2 0 Cation efflux family TMEM238 PF15125.6 PVD38662.1 - 0.038 14.2 0.2 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 TMEM238 protein family PMT_4TMC PF16192.5 PVD38662.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.4 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase Tetraspanin PF00335.20 PVD38662.1 - 0.085 12.6 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family TMEM72 PF16054.5 PVD38662.1 - 0.09 12.5 0.2 0.65 9.7 0.0 2.0 1 1 1 2 2 2 0 Transmembrane protein family 72 TCR_zetazeta PF11628.8 PVD38662.1 - 0.11 12.2 0.3 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Erp_C PF06780.11 PVD38662.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Erp protein C-terminus SdpI PF13630.6 PVD38662.1 - 0.13 12.4 0.9 1 9.5 0.0 2.1 1 1 1 2 2 2 0 SdpI/YhfL protein family zf-LITAF-like PF10601.9 PVD38663.1 - 7.7e-25 87.0 16.6 1.1e-24 86.4 16.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 PVD38663.1 - 0.0093 16.1 3.3 0.58 10.3 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain zinc_ribbon_2 PF13240.6 PVD38663.1 - 0.012 15.4 2.4 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.11 PVD38663.1 - 0.048 13.2 2.4 0.44 10.1 0.5 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 PVD38663.1 - 0.08 12.5 1.5 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF5318 PF17249.2 PVD38663.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5318) Beta_elim_lyase PF01212.21 PVD38664.1 - 9.3e-87 291.0 0.3 1.2e-86 290.7 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PVD38664.1 - 1.6e-08 34.1 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II TK PF00265.18 PVD38666.1 - 5.2e-46 156.7 0.2 2.6e-23 82.8 0.0 2.1 1 1 1 2 2 2 2 Thymidine kinase DUF4201 PF13870.6 PVD38667.1 - 3.9e-45 153.8 32.7 3.9e-45 153.8 32.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) SBDS_C PF09377.10 PVD38667.1 - 0.25 11.4 3.5 0.72 9.9 3.5 1.7 1 1 0 1 1 1 0 SBDS protein C-terminal domain SH2 PF00017.24 PVD38668.1 - 4.5e-05 23.5 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain FPL PF09758.9 PVD38671.1 - 6e-63 211.3 11.3 1.2e-62 210.3 11.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein Trypsin PF00089.26 PVD38673.1 - 5.8e-34 117.8 0.0 1e-33 117.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin Fz PF01392.22 PVD38673.1 - 1.5e-33 115.7 11.3 5.6e-21 75.2 2.8 3.2 3 0 0 3 3 3 2 Fz domain Ldl_recept_a PF00057.18 PVD38673.1 - 2.5e-09 37.2 35.6 8.5e-09 35.5 13.1 3.5 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SEA PF01390.20 PVD38673.1 - 4e-09 36.5 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 SEA domain SRCR_2 PF15494.6 PVD38673.1 - 7.6e-06 26.4 0.4 1.8e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PVD38673.1 - 0.00019 21.9 0.1 0.00019 21.9 0.1 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 PVD38673.1 - 0.0002 21.7 0.0 0.00056 20.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.10 PVD38673.1 - 0.00099 19.6 0.0 0.0029 18.1 0.0 1.8 1 0 0 1 1 1 1 Hepsin, SRCR domain Trypsin_2 PF13365.6 PVD38673.1 - 0.0094 16.9 0.0 0.029 15.3 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Sigma_reg_N PF13800.6 PVD38673.1 - 0.16 12.3 1.4 0.31 11.3 1.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Pro_isomerase PF00160.21 PVD38674.1 - 8.6e-49 165.8 0.6 9.5e-49 165.7 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 PVD38675.1 - 2.3e-47 161.2 0.3 2.6e-47 161.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ PF00595.24 PVD38676.1 - 9.7e-51 170.1 6.4 4.9e-15 55.6 0.1 5.7 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 PVD38676.1 - 6.8e-23 80.3 0.0 1.8e-05 24.5 0.0 5.0 5 0 0 5 5 5 4 PDZ domain Guanylate_kin PF00625.21 PVD38676.1 - 8.2e-09 35.4 0.1 8.2e-09 35.4 0.1 4.4 4 1 0 4 4 4 1 Guanylate kinase PDZ_2 PF13180.6 PVD38676.1 - 2.5e-08 34.1 3.0 0.11 12.8 0.0 5.9 5 1 1 6 6 6 3 PDZ domain Spc7 PF08317.11 PVD38676.1 - 0.00025 20.1 10.9 0.00025 20.1 10.9 5.0 2 1 3 5 5 5 2 Spc7 kinetochore protein SH3_2 PF07653.17 PVD38676.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MAD PF05557.13 PVD38677.1 - 2.2e-119 399.7 98.7 2.7e-119 399.5 98.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Shugoshin_N PF07558.11 PVD38677.1 - 0.0085 15.9 0.6 0.0085 15.9 0.6 5.3 5 0 0 5 5 5 1 Shugoshin N-terminal coiled-coil region GIT1_C PF12205.8 PVD38677.1 - 0.0093 16.1 1.7 0.0093 16.1 1.7 4.9 3 1 1 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term FMN_dh PF01070.18 PVD38677.1 - 4.7 6.1 9.1 0.18 10.8 2.1 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF948 PF06103.11 PVD38677.1 - 9.2 6.6 20.9 1.9 8.8 2.9 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RF-1 PF00472.20 PVD38678.1 - 1.5e-20 73.3 0.6 2e-20 72.9 0.6 1.1 1 0 0 1 1 1 1 RF-1 domain RapH_N PF18801.1 PVD38678.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal ParA PF10609.9 PVD38679.1 - 4.5e-85 285.0 0.0 5.5e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DNA_pol3_delt_C PF14840.6 PVD38679.1 - 0.084 13.2 0.1 0.41 11.0 0.0 2.1 2 1 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term Tektin PF03148.14 PVD38680.1 - 1.9e-143 477.9 34.5 2.2e-143 477.7 34.5 1.0 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.12 PVD38680.1 - 0.18 11.8 8.9 2.4 8.2 1.9 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Noelin-1 PF12308.8 PVD38680.1 - 1.2 9.1 5.0 9.6 6.3 0.9 2.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein ApoLp-III PF07464.11 PVD38680.1 - 2.3 8.3 8.3 5.4 7.1 4.6 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Plk4_PB2 PF18409.1 PVD38680.1 - 5 7.9 8.6 8.9 7.0 0.5 3.5 3 2 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 CENP-F_leu_zip PF10473.9 PVD38680.1 - 5 7.2 18.1 3.5 7.6 0.7 3.7 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.11 PVD38680.1 - 6.7 7.3 20.9 0.4 11.3 3.2 4.5 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Ank_2 PF12796.7 PVD38681.1 - 8.6e-11 42.3 0.0 4.1e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ion_trans PF00520.31 PVD38681.1 - 5.4e-10 38.9 9.8 9.7e-10 38.1 9.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 PVD38681.1 - 9.6e-05 22.7 4.3 0.48 11.0 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 PVD38681.1 - 0.00013 22.2 0.4 0.036 14.4 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD38681.1 - 0.00013 22.5 0.4 0.27 11.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38681.1 - 0.00047 20.4 0.4 1.9 9.3 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat MerE PF05052.12 PVD38681.1 - 0.011 15.6 1.1 3.5 7.6 0.0 3.3 3 0 0 3 3 3 0 MerE protein Sulf_transp PF04143.14 PVD38681.1 - 0.37 10.3 3.8 0.61 9.6 3.8 1.3 1 0 0 1 1 1 0 Sulphur transport LUC7 PF03194.15 PVD38682.1 - 1.4e-73 247.7 11.2 1.4e-73 247.7 11.2 1.8 2 0 0 2 2 2 1 LUC7 N_terminus ZapB PF06005.12 PVD38682.1 - 0.25 11.8 14.8 2 8.9 0.1 3.5 3 0 0 3 3 3 0 Cell division protein ZapB YtxH PF12732.7 PVD38682.1 - 6.6 7.3 5.7 3.7 8.2 2.6 2.1 2 0 0 2 2 2 0 YtxH-like protein Acyl_transf_1 PF00698.21 PVD38683.1 - 2.4e-80 270.4 0.0 3.9e-80 269.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 PVD38683.1 - 5.2e-70 235.9 0.0 8.6e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PVD38683.1 - 2e-47 161.4 0.0 5.3e-47 160.0 0.0 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 PVD38683.1 - 6.7e-39 132.6 0.1 1.3e-38 131.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 PVD38683.1 - 5e-35 120.3 0.0 1.7e-34 118.6 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 PVD38683.1 - 8.1e-24 85.0 0.0 1.9e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 PVD38683.1 - 1.2e-15 57.5 0.0 2.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 PVD38683.1 - 4e-15 55.9 0.0 1.7e-14 53.9 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PVD38683.1 - 4.9e-14 53.5 0.0 2.7e-13 51.1 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 PVD38683.1 - 2.7e-11 43.7 0.4 7.4e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 PVD38683.1 - 1.4e-10 40.9 0.2 6.3e-09 35.6 0.0 2.7 2 1 1 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.6 PVD38683.1 - 1.9e-07 31.1 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 PVD38683.1 - 4.3e-05 23.0 0.0 0.00017 21.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 PVD38683.1 - 0.0017 18.2 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain YjeF_N PF03853.15 PVD38683.1 - 0.027 14.4 0.7 0.3 10.9 0.0 3.0 3 0 0 3 3 3 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 PVD38683.1 - 0.037 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PVD38683.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_12 PF08242.12 PVD38683.1 - 0.13 13.0 0.1 0.65 10.8 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Flavodoxin_3 PF12641.7 PVD38683.1 - 0.19 11.4 0.2 27 4.4 0.0 3.3 4 0 0 4 4 4 0 Flavodoxin domain B277 PF17623.2 PVD38683.1 - 0.21 10.6 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Arfaptin PF06456.13 PVD38684.1 - 6.9e-79 264.6 4.0 1.1e-78 264.0 4.0 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.24 PVD38684.1 - 3.4e-12 46.5 0.1 8.8e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD38684.1 - 3.1e-11 43.0 0.3 6e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD38684.1 - 3.5e-07 30.5 0.1 9e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain BAR PF03114.18 PVD38684.1 - 2.7e-06 27.2 6.7 6.5e-06 26.0 5.1 2.2 1 1 1 2 2 2 1 BAR domain BAR_3 PF16746.5 PVD38684.1 - 2.7e-05 24.0 3.5 0.0011 18.7 3.5 2.1 1 1 0 1 1 1 1 BAR domain of APPL family GRASP55_65 PF04495.14 PVD38684.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain SPRY PF00622.28 PVD38685.1 - 7.9e-19 67.9 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 PVD38685.1 - 0.029 14.7 1.0 0.052 13.9 1.0 1.4 1 0 0 1 1 1 0 SOCS box KRAP_IP3R_bind PF14722.6 PVD38686.1 - 6.3e-08 32.5 0.0 2e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain SSFA2_C PF14723.6 PVD38686.1 - 2.1e-05 24.5 0.9 2.1e-05 24.5 0.9 3.0 3 0 0 3 3 3 1 Sperm-specific antigen 2 C-terminus RTP1_C1 PF10363.9 PVD38686.1 - 0.11 12.7 0.1 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Plectin PF00681.20 PVD38687.1 - 1.1e-31 108.5 5.4 3.9e-06 26.6 0.0 11.2 8 2 3 11 11 11 9 Plectin repeat SH3_10 PF17902.1 PVD38687.1 - 1.1e-15 57.5 1.0 2.6e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain ECH_1 PF00378.20 PVD38687.1 - 0.013 14.8 0.0 2.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase Spectrin PF00435.21 PVD38688.1 - 3.9e-10 40.2 35.4 7.7e-05 23.1 5.6 4.9 2 1 2 5 5 5 3 Spectrin repeat Plectin PF00681.20 PVD38688.1 - 2.4e-08 33.7 0.0 0.13 12.1 0.0 5.6 4 1 1 5 5 5 2 Plectin repeat MSA-2c PF12238.8 PVD38688.1 - 0.0016 18.5 1.4 0.0034 17.4 1.4 1.5 1 0 0 1 1 1 1 Merozoite surface antigen 2c Med22 PF06179.12 PVD38688.1 - 0.0098 16.1 4.5 0.031 14.5 0.4 3.0 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex Laminin_II PF06009.12 PVD38688.1 - 0.05 13.6 0.6 0.05 13.6 0.6 3.7 2 1 2 4 4 4 0 Laminin Domain II NTP_transf_4 PF13562.6 PVD38688.1 - 0.27 11.4 7.1 1.4 9.1 0.7 2.7 3 0 0 3 3 3 0 Sugar nucleotidyl transferase Synaptobrevin PF00957.21 PVD38688.1 - 0.82 9.5 4.0 6.3 6.7 0.8 2.9 2 0 0 2 2 2 0 Synaptobrevin Spectrin PF00435.21 PVD38689.1 - 1.6e-55 186.1 58.3 1.9e-10 41.1 3.9 9.6 8 1 2 10 10 10 8 Spectrin repeat ZnuA PF01297.17 PVD38689.1 - 0.1 12.0 9.7 1.2 8.4 1.0 3.7 3 1 0 3 3 3 0 Zinc-uptake complex component A periplasmic Laminin_II PF06009.12 PVD38689.1 - 0.11 12.6 0.1 0.11 12.6 0.1 8.3 4 3 4 8 8 8 0 Laminin Domain II AAA_13 PF13166.6 PVD38689.1 - 0.29 9.7 45.4 0.0081 14.9 8.0 5.0 2 1 3 5 5 5 0 AAA domain MCR_C PF04609.12 PVD38689.1 - 2.4 7.1 9.1 2.5 7.1 0.2 3.8 4 0 0 4 4 4 0 Methyl-coenzyme M reductase operon protein C TFA2_Winged_2 PF18121.1 PVD38689.1 - 2.8 7.7 5.9 0.71 9.6 0.2 3.2 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 GAS2 PF02187.17 PVD38690.1 - 6e-27 93.5 0.0 1.3e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.21 PVD38690.1 - 5.2e-22 78.3 20.8 1e-11 45.2 3.5 4.7 3 2 0 3 3 3 3 Spectrin repeat EF-hand_6 PF13405.6 PVD38690.1 - 2.8e-09 36.1 3.5 0.00028 20.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PVD38690.1 - 1.5e-08 33.6 9.2 0.00027 20.3 0.7 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PVD38690.1 - 1.3e-07 31.9 2.5 1.3e-07 31.9 2.5 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD38690.1 - 4.3e-06 26.5 6.3 0.0011 18.8 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair ApoLp-III PF07464.11 PVD38690.1 - 0.058 13.5 0.7 0.23 11.6 0.7 2.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) XhlA PF10779.9 PVD38690.1 - 0.17 12.1 0.8 11 6.3 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA YscO-like PF16789.5 PVD38690.1 - 0.21 11.6 4.5 0.45 10.5 4.5 1.6 1 0 0 1 1 1 0 YscO-like protein EF-hand_5 PF13202.6 PVD38690.1 - 3.2 7.4 11.0 0.044 13.3 1.1 3.0 3 0 0 3 3 3 0 EF hand Homeodomain PF00046.29 PVD38692.1 - 7.3e-24 83.4 5.8 7.3e-24 83.4 5.8 2.0 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 PVD38692.1 - 1.3e-06 28.0 1.7 3e-06 26.8 1.7 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 PVD38692.1 - 0.032 14.1 0.1 0.085 12.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain AAA PF00004.29 PVD38693.1 - 2.8e-14 53.7 0.0 1.1e-13 51.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PVD38693.1 - 2.7e-07 30.7 0.0 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PVD38693.1 - 3.6e-06 26.8 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD38693.1 - 4e-06 27.2 0.0 0.00011 22.5 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PVD38693.1 - 0.0004 20.5 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PVD38693.1 - 0.00069 19.6 0.2 0.15 12.0 0.0 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 PVD38693.1 - 0.00082 19.3 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 PVD38693.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 PVD38693.1 - 0.0026 18.2 0.0 0.28 11.6 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 PVD38693.1 - 0.0037 17.8 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_8 PF12780.7 PVD38693.1 - 0.0047 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_24 PF13479.6 PVD38693.1 - 0.0092 15.7 0.3 0.078 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PVD38693.1 - 0.012 15.2 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 PVD38693.1 - 0.014 15.3 0.1 0.075 12.9 0.0 2.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PVD38693.1 - 0.024 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PVD38693.1 - 0.03 14.8 0.3 0.31 11.5 0.0 2.7 2 1 0 2 2 2 0 ABC transporter NAD_binding_1 PF00175.21 PVD38693.1 - 0.033 14.8 0.2 3.5 8.3 0.0 3.2 3 1 0 3 3 3 0 Oxidoreductase NAD-binding domain IstB_IS21 PF01695.17 PVD38693.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PVD38693.1 - 0.1 12.9 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2452 PF10504.9 PVD38694.1 - 0.027 13.9 0.2 0.044 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Dynamitin PF04912.14 PVD38694.1 - 0.034 13.5 0.8 0.044 13.1 0.7 1.3 1 1 0 1 1 1 0 Dynamitin DUF3955 PF13127.6 PVD38695.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) DUF4371 PF14291.6 PVD38696.1 - 0.00024 20.8 0.1 0.00032 20.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) N_Asn_amidohyd PF14736.6 PVD38697.1 - 4.7e-51 173.5 0.0 6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase adh_short_C2 PF13561.6 PVD38697.1 - 1.2e-19 70.8 0.2 2.1e-19 70.1 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PVD38697.1 - 4.5e-19 68.7 0.2 7e-19 68.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase FIST PF08495.10 PVD38697.1 - 0.0098 15.9 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 FIST N domain CotH PF08757.11 PVD38697.1 - 0.23 10.9 0.0 0.46 10.0 0.0 1.4 2 0 0 2 2 2 0 CotH kinase protein RRN3 PF05327.11 PVD38698.1 - 1.1e-105 354.3 15.1 3.4e-105 352.7 15.1 1.6 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 YWFCY PF14293.6 PVD38698.1 - 0.53 10.6 2.5 2 8.8 0.0 3.0 3 0 0 3 3 3 0 YWFCY protein Coilin_N PF15862.5 PVD38699.1 - 1.9e-08 34.2 3.3 1e-07 31.8 3.3 2.2 1 1 0 1 1 1 1 Coilin N-terminus Myelin-PO_C PF10570.9 PVD38701.1 - 0.017 15.5 2.1 1.1e+02 3.3 0.0 5.2 5 1 1 6 6 6 0 Myelin-PO cytoplasmic C-term p65 binding region partial_CstF PF15861.5 PVD38701.1 - 1.3 8.8 8.3 16 5.4 0.0 4.0 4 0 0 4 4 4 0 Partial cleavage stimulation factor domain 2-Hacid_dh_C PF02826.19 PVD38702.1 - 3.2e-19 69.0 0.0 4.6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 PVD38704.1 - 2e-17 63.6 0.2 6e-11 42.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38704.1 - 4.8e-11 43.0 4.7 1.6e-06 28.5 0.1 3.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38704.1 - 3.6e-09 36.1 0.1 0.0021 18.4 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD38704.1 - 2e-08 34.3 2.2 0.003 17.8 0.0 3.8 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 PVD38704.1 - 2.6e-08 34.0 0.1 0.0065 16.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SAM_1 PF00536.30 PVD38704.1 - 1.6e-07 31.6 0.0 4.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 PVD38705.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD38705.1 - 0.06 14.2 0.1 0.13 13.2 0.0 1.6 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4588 PF15251.6 PVD38706.1 - 7.4e-15 55.4 0.5 9e-15 55.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF4588 PF15251.6 PVD38707.1 - 4.9e-15 56.0 0.1 5.8e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Thiol_cytolysin PF01289.19 PVD38707.1 - 0.037 12.9 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin VHS PF00790.19 PVD38708.1 - 2.2e-39 134.5 0.1 1.5e-38 131.8 0.0 2.2 2 1 0 2 2 2 1 VHS domain GGA_N-GAT PF18308.1 PVD38708.1 - 1.9e-20 72.2 4.4 3.9e-20 71.2 4.4 1.6 1 0 0 1 1 1 1 GGA N-GAT domain Alpha_adaptinC2 PF02883.20 PVD38708.1 - 2.6e-18 66.3 0.3 8.5e-18 64.7 0.3 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 PVD38708.1 - 3.2e-14 53.0 0.9 3.2e-14 53.0 0.9 2.0 2 0 0 2 2 2 1 GAT domain Mer2 PF09074.10 PVD38708.1 - 0.043 13.6 5.4 0.083 12.7 5.4 1.4 1 0 0 1 1 1 0 Mer2 RTTN_N PF14726.6 PVD38708.1 - 0.057 14.2 0.1 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DUF1722 PF08349.11 PVD38708.1 - 0.17 12.2 0.3 0.74 10.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Ank_2 PF12796.7 PVD38709.1 - 6.8e-100 327.8 11.7 4.9e-15 55.9 0.3 8.3 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38709.1 - 3.6e-81 266.6 29.9 6.7e-10 39.3 0.1 11.2 3 3 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 PVD38709.1 - 2.2e-78 255.6 14.7 9.9e-06 25.8 0.1 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_5 PF13857.6 PVD38709.1 - 3.1e-78 256.8 9.4 5.9e-11 42.4 0.1 9.9 5 4 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38709.1 - 3.2e-69 220.6 11.9 4.8e-05 23.4 0.1 15.3 15 0 0 15 15 15 13 Ankyrin repeat IQ PF00612.27 PVD38709.1 - 0.0011 18.6 0.3 0.0035 17.0 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-H2C2_2 PF13465.6 PVD38710.1 - 4.6e-13 48.9 7.1 1.5e-07 31.5 0.8 5.1 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 PVD38710.1 - 8.8e-13 48.0 33.4 6e-06 26.4 1.0 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD38710.1 - 1e-07 32.1 30.2 8.5e-05 23.1 1.4 4.5 5 0 0 5 5 3 3 C2H2-type zinc finger zf-met PF12874.7 PVD38710.1 - 0.00031 21.0 5.0 0.14 12.5 0.5 4.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PVD38710.1 - 0.00069 19.9 1.7 0.00069 19.9 1.7 2.9 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PVD38710.1 - 0.0022 18.2 5.0 0.93 9.9 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 PVD38710.1 - 0.014 15.8 2.8 0.32 11.5 0.2 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 PVD38710.1 - 0.02 14.9 13.4 0.12 12.4 0.4 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 PVD38710.1 - 0.044 13.9 4.1 0.093 12.9 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 PVD38710.1 - 0.07 13.1 0.8 0.07 13.1 0.8 3.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 PVD38710.1 - 0.54 10.1 13.0 0.4 10.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 PVD38710.1 - 0.68 10.6 14.6 4.9 7.9 0.2 4.2 3 1 1 4 4 4 0 FOXP coiled-coil domain Gelsolin PF00626.22 PVD38711.1 - 2.4e-22 78.6 0.2 1.5e-06 28.0 0.0 5.5 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 PVD38711.1 - 3.7e-17 62.1 5.0 5.2e-17 61.6 3.3 2.2 2 0 0 2 2 2 1 Villin headpiece domain DUF3855 PF12967.7 PVD38711.1 - 0.076 13.0 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) DUF5525 PF17663.1 PVD38711.1 - 0.2 9.7 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DUF4695 PF15766.5 PVD38712.1 - 0.061 13.6 0.2 0.061 13.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) DUF4695 PF15766.5 PVD38713.1 - 0.02 15.1 12.3 0.13 12.5 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4695) DUF2550 PF10739.9 PVD38715.1 - 0.093 12.7 0.8 0.28 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) EphA2_TM PF14575.6 PVD38717.1 - 0.055 14.4 0.3 0.11 13.4 0.3 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 PVD38717.1 - 0.44 11.0 4.2 0.94 9.9 4.2 1.6 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Mid2 PF04478.12 PVD38717.1 - 0.93 9.3 5.0 2.3 8.1 5.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 PVD38717.1 - 1.8 8.5 3.9 4 7.4 3.9 1.5 1 0 0 1 1 1 0 Syndecan domain PRAS PF15798.5 PVD38718.1 - 2 9.0 5.2 28 5.3 0.0 3.0 3 1 1 4 4 4 0 Proline-rich AKT1 substrate 1 TFR_dimer PF04253.15 PVD38719.1 - 4.2e-08 33.3 0.0 5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF4538 PF15061.6 PVD38719.1 - 0.15 11.9 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) MCD PF05292.11 PVD38719.1 - 0.18 11.4 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Phage_T4_Ndd PF06591.11 PVD38719.1 - 0.21 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Peptidase_M28 PF04389.17 PVD38721.1 - 7.7e-19 68.2 0.0 1.3e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 PVD38721.1 - 1.1e-08 35.0 0.0 3.5e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 PA domain Band_7 PF01145.25 PVD38723.1 - 4.6e-19 69.1 0.1 4.6e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family LOR PF04525.12 PVD38723.1 - 0.19 11.3 6.1 0.26 10.9 0.1 2.4 2 0 0 2 2 2 0 LURP-one-related DUF2031 PF09592.10 PVD38723.1 - 0.27 10.7 9.5 0.59 9.6 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) WAPL PF07814.13 PVD38725.1 - 7.6e-94 314.5 3.7 7.6e-94 314.5 3.7 1.9 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 PVD38725.1 - 0.0021 17.3 0.2 0.005 16.1 0.2 1.6 1 0 0 1 1 1 1 Wap1 domain zf-C2H2 PF00096.26 PVD38729.1 - 0.0002 21.6 3.1 0.0002 21.6 0.2 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD38729.1 - 0.0018 19.0 0.1 0.0018 19.0 0.1 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PVD38729.1 - 0.006 16.5 0.2 0.024 14.6 0.2 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger S100PBPR PF15427.6 PVD38730.1 - 0.089 12.0 14.3 0.11 11.7 14.3 1.1 1 0 0 1 1 1 0 S100P-binding protein Endomucin PF07010.12 PVD38730.1 - 0.58 10.1 24.0 0.77 9.7 24.0 1.2 1 0 0 1 1 1 0 Endomucin Macoilin PF09726.9 PVD38730.1 - 4.5 5.7 21.5 5.4 5.5 21.5 1.1 1 0 0 1 1 1 0 Macoilin family MPTase-PolyVal PF18818.1 PVD38732.1 - 0.012 15.7 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase superfamily domain Claudin_2 PF13903.6 PVD38732.1 - 0.025 14.3 0.2 0.032 14.0 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Thia_YuaJ PF09515.10 PVD38732.1 - 0.04 13.9 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) DuoxA PF10204.9 PVD38732.1 - 0.058 12.4 0.2 0.075 12.0 0.2 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor Heliorhodopsin PF18761.1 PVD38732.1 - 0.074 12.3 0.1 0.091 12.1 0.1 1.0 1 0 0 1 1 1 0 Heliorhodopsin DUF2975 PF11188.8 PVD38732.1 - 0.094 12.6 0.6 1.8 8.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) PMP22_Claudin PF00822.20 PVD38733.1 - 0.00063 19.7 0.0 0.00082 19.3 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD38733.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 PVD38733.1 - 0.069 12.2 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor S1FA PF04689.13 PVD38735.1 - 0.03 14.5 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA PMP22_Claudin PF00822.20 PVD38735.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family NCE101 PF11654.8 PVD38735.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 TrbC PF04956.13 PVD38736.1 - 0.077 13.2 1.6 0.12 12.6 1.6 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family PMP22_Claudin PF00822.20 PVD38737.1 - 2.7e-07 30.6 0.2 2.9e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD38737.1 - 4.2e-06 26.7 0.1 4.7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction YopE PF03545.13 PVD38737.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Acetyltransf_7 PF13508.7 PVD38737.1 - 0.16 12.4 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro81C PF17652.1 PVD38741.1 - 4e-51 174.3 0.1 8.8e-51 173.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PVD38741.1 - 5.3e-12 45.5 0.1 4.6e-07 29.3 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain Ribosomal_L10 PF00466.20 PVD38741.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Hyccin PF09790.9 PVD38742.1 - 3e-90 302.6 0.0 3.9e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Hyccin Endostatin PF06482.11 PVD38743.1 - 5.8e-68 229.7 1.3 6.5e-68 229.5 1.3 1.0 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 PVD38743.1 - 0.00012 21.9 3.1 0.0025 17.6 3.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) Ald_Xan_dh_C2 PF02738.18 PVD38748.1 - 4.9e-136 454.4 0.3 6.5e-136 454.0 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PVD38748.1 - 4.7e-22 78.4 0.1 1.3e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PVD38749.1 - 8.8e-29 99.4 0.1 2.8e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 PVD38749.1 - 2.6e-25 89.1 0.0 5.9e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PVD38749.1 - 1.4e-16 60.5 0.0 2.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PVD38749.1 - 0.00053 19.9 1.5 0.00053 19.9 1.5 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Ank_2 PF12796.7 PVD38750.1 - 1e-65 218.3 15.5 8.1e-19 68.0 0.5 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD38750.1 - 2.3e-47 158.8 20.1 2.3e-12 47.2 0.0 7.6 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PVD38750.1 - 2.8e-43 144.5 14.6 5.7e-07 29.7 0.3 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 PVD38750.1 - 1.1e-36 120.7 11.2 5.9e-05 23.2 0.2 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 PVD38750.1 - 6.9e-34 115.5 14.1 1.1e-08 35.1 0.5 8.0 2 1 6 9 9 9 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD38750.1 - 0.054 13.9 0.3 0.1 13.0 0.3 1.4 1 0 0 1 1 1 0 SOCS box EGF PF00008.27 PVD38751.1 - 0.17 12.3 7.9 0.39 11.1 7.9 1.7 1 0 0 1 1 1 0 EGF-like domain Pkinase PF00069.25 PVD38752.1 - 5.8e-79 265.2 0.0 9.2e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38752.1 - 6.8e-37 127.2 0.0 2.8e-36 125.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PVD38752.1 - 1.1e-06 27.8 0.5 1.1e-06 27.8 0.5 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PVD38752.1 - 0.017 14.4 0.0 0.054 12.8 0.0 1.8 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 PVD38752.1 - 0.038 13.9 0.0 0.33 10.9 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PVD38752.1 - 0.088 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SH2 PF00017.24 PVD38753.1 - 6.3e-18 64.7 0.3 1.8e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 SH2 domain RINGv PF12906.7 PVD38754.1 - 2.2e-15 56.5 12.5 4.7e-15 55.4 12.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PVD38754.1 - 0.035 14.4 10.6 0.035 14.4 10.6 1.9 2 0 0 2 2 2 0 Ring finger domain DUF587 PF04532.12 PVD38754.1 - 0.12 11.7 3.1 0.14 11.4 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF587) zf-C3HC4 PF00097.25 PVD38754.1 - 2.3 8.1 8.5 22 5.1 8.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PTEN_C2 PF10409.9 PVD38755.1 - 6.2e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 PVD38755.1 - 6.3e-06 26.0 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PVD38755.1 - 0.00082 19.4 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PVD38755.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PVD38755.1 - 0.004 16.7 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Requiem_N PF14051.6 PVD38756.1 - 2.1e-29 101.5 1.4 5.7e-29 100.1 1.4 1.8 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 PVD38756.1 - 3.3e-22 78.1 23.2 6.8e-13 48.3 4.5 3.4 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 PVD38756.1 - 0.0025 17.9 6.8 0.0025 17.9 6.8 3.3 2 1 1 3 3 2 1 PHD-finger Prok-RING_1 PF14446.6 PVD38756.1 - 0.014 15.3 0.6 0.014 15.3 0.6 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 PVD38756.1 - 0.13 11.8 12.2 0.23 11.1 1.8 3.0 2 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Lar_restr_allev PF14354.6 PVD38756.1 - 0.22 11.9 14.5 1.8e+02 2.6 11.8 3.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar GATA PF00320.27 PVD38756.1 - 0.39 10.3 0.1 0.39 10.3 0.1 3.2 3 0 0 3 3 3 0 GATA zinc finger C1_1 PF00130.22 PVD38756.1 - 0.47 10.4 20.6 0.21 11.5 0.6 4.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_C2H2_ZHX PF18387.1 PVD38756.1 - 1.4 8.7 4.2 0.47 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PHD_2 PF13831.6 PVD38756.1 - 2.6 7.7 20.6 0.072 12.7 0.7 4.0 3 1 1 4 4 4 0 PHD-finger zf-RING_7 PF02591.15 PVD38756.1 - 2.9 8.2 10.3 7.3 6.9 0.1 3.8 3 1 0 3 3 3 0 C4-type zinc ribbon domain SapB_2 PF03489.17 PVD38757.1 - 1e-64 214.2 48.4 1.3e-11 44.4 2.8 8.8 8 0 0 8 8 8 7 Saposin-like type B, region 2 SapB_1 PF05184.15 PVD38757.1 - 2e-52 174.7 47.5 1.1e-12 47.7 4.8 7.7 6 0 0 6 6 6 6 Saposin-like type B, region 1 SapA PF02199.15 PVD38757.1 - 8.5e-09 35.6 3.7 8.5e-09 35.6 3.7 4.1 4 0 0 4 4 4 1 Saposin A-type domain DUF5567 PF17722.1 PVD38757.1 - 0.065 13.1 1.2 3.1 7.6 0.1 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5567) Thioredoxin_3 PF13192.6 PVD38757.1 - 0.25 11.4 19.1 2.2 8.4 0.1 5.9 6 0 0 6 6 6 0 Thioredoxin domain SH3_15 PF18346.1 PVD38758.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Sigma70_ner PF04546.13 PVD38758.1 - 0.49 10.2 10.6 0.11 12.4 3.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.13 PVD38758.1 - 1.3 9.1 17.3 4 7.5 2.5 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.12 PVD38758.1 - 2.4 6.2 14.0 4.7 5.3 0.3 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 PVD38758.1 - 8.1 4.6 16.0 2.9 6.1 2.4 2.2 2 0 0 2 2 2 0 CDC45-like protein UQ_con PF00179.26 PVD38759.1 - 1.1e-28 99.6 0.0 2.8e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Myosin_tail_1 PF01576.19 PVD38760.1 - 0 1265.5 304.6 0 1265.0 304.6 1.2 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 PVD38760.1 - 4.4e-165 550.7 0.7 6.4e-153 510.5 0.1 4.7 3 2 1 4 4 4 2 Myosin head (motor domain) AAA_15 PF13175.6 PVD38760.1 - 0.0034 17.2 9.5 0.0034 17.2 9.5 5.7 1 1 2 4 4 4 1 AAA ATPase domain IQ PF00612.27 PVD38760.1 - 0.097 12.5 0.9 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif MMR_HSR1 PF01926.23 PVD38763.1 - 1.1e-22 80.3 0.0 2.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PVD38763.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PVD38763.1 - 6.4e-05 23.1 1.5 0.26 11.3 0.1 2.5 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 PVD38763.1 - 0.003 17.5 0.7 0.0097 15.8 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PVD38763.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 PVD38763.1 - 0.022 15.0 1.5 0.032 14.5 0.1 1.9 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 PVD38763.1 - 0.025 13.6 0.2 0.088 11.8 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PVD38763.1 - 0.027 14.8 0.0 0.047 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 PVD38763.1 - 0.029 13.8 0.7 0.18 11.2 0.0 2.2 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 PVD38763.1 - 0.052 14.1 0.1 0.091 13.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 PVD38763.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PVD38763.1 - 0.066 12.5 0.1 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 AIG1 family MCM PF00493.23 PVD38763.1 - 0.073 12.2 0.2 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain CtaG_Cox11 PF04442.14 PVD38764.1 - 1.1e-65 220.3 0.8 1.3e-65 220.0 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Fascin PF06268.13 PVD38765.1 - 1.1e-63 212.4 2.0 8.6e-26 90.3 0.1 4.2 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 PVD38765.1 - 5.7e-12 45.7 0.1 0.00034 20.4 0.0 4.4 1 1 4 5 5 5 4 FRG1-like domain 2OG-FeII_Oxy_2 PF13532.6 PVD38766.1 - 1.7e-07 31.6 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_MCEL PF03291.16 PVD38766.1 - 0.086 11.9 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 mRNA capping enzyme zf-TRAF PF02176.18 PVD38767.1 - 2e-09 38.0 3.7 2e-09 38.0 3.7 3.9 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 PVD38767.1 - 3.6e-07 29.9 11.3 3.6e-07 29.9 11.3 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD38767.1 - 2.4e-06 27.3 9.5 2.4e-06 27.3 9.5 4.4 4 2 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PVD38767.1 - 3.6e-05 23.5 11.3 3.6e-05 23.5 11.3 4.6 5 1 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 PVD38767.1 - 7.1e-05 23.2 5.9 7.1e-05 23.2 5.9 3.2 4 0 0 4 4 4 1 TRAF-like zinc-finger Prok-RING_4 PF14447.6 PVD38767.1 - 0.00011 21.9 10.6 0.00011 21.9 10.6 3.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PVD38767.1 - 0.00041 20.3 5.2 0.00041 20.3 5.2 3.8 3 2 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 PVD38767.1 - 0.00083 19.6 9.6 0.00083 19.6 9.6 4.2 3 1 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 PVD38767.1 - 0.0018 18.2 10.2 0.0018 18.2 10.2 4.5 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD38767.1 - 0.0034 17.5 9.1 0.0034 17.5 9.1 3.3 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PVD38767.1 - 0.014 15.2 2.8 0.014 15.2 2.8 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 PVD38767.1 - 0.016 15.0 5.8 0.016 15.0 5.8 3.2 4 1 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit ADK_lid PF05191.14 PVD38767.1 - 5.8 7.0 9.0 27 4.8 0.4 3.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-ANAPC11 PF12861.7 PVD38767.1 - 6.5 6.9 16.4 0.24 11.5 3.7 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger NUDIX PF00293.28 PVD38768.1 - 3.3e-13 49.8 0.1 4.2e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain RPN7 PF10602.9 PVD38769.1 - 3.9e-63 212.3 0.8 1e-62 210.9 0.9 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 PVD38769.1 - 6e-20 71.7 0.3 1.4e-18 67.4 0.1 2.4 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 PVD38769.1 - 0.0013 18.7 2.3 0.11 12.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PVD38769.1 - 0.034 13.8 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 PVD38769.1 - 0.098 12.5 1.8 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 PVD38770.1 - 0 1083.5 7.1 0 1083.3 7.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Sec2p PF06428.11 PVD38770.1 - 0.0013 18.6 7.7 0.25 11.3 6.2 2.5 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p RPW8 PF05659.11 PVD38770.1 - 0.054 13.2 0.3 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 PVD38770.1 - 1.1 9.2 4.7 0.42 10.6 1.8 1.7 2 0 0 2 2 2 0 Laminin Domain II TMF_TATA_bd PF12325.8 PVD38770.1 - 4.6 7.5 10.0 1 9.6 5.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 PVD38770.1 - 5.5 7.5 6.8 2.6 8.5 2.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TniB PF05621.11 PVD38771.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein WD40 PF00400.32 PVD38772.1 - 1.9e-46 155.0 30.2 0.00015 22.5 0.0 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD38772.1 - 7.9e-11 42.1 1.6 0.82 10.0 0.0 6.9 4 2 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.11 PVD38772.1 - 6.7e-10 39.0 0.4 1.8e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Nup160 PF11715.8 PVD38772.1 - 4e-05 22.5 8.0 1.4 7.5 0.0 5.8 4 1 1 6 6 6 3 Nucleoporin Nup120/160 YmzC PF14157.6 PVD38772.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 YmzC-like protein LPD24 PF18839.1 PVD38772.1 - 0.086 13.1 0.1 5.5 7.3 0.0 2.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Hira PF07569.11 PVD38772.1 - 0.14 11.9 2.8 41 3.8 0.0 4.0 4 0 0 4 4 4 0 TUP1-like enhancer of split Annexin PF00191.20 PVD38773.1 - 2.8e-94 309.2 14.5 7.1e-26 90.1 0.1 4.2 4 0 0 4 4 4 4 Annexin SR-25 PF10500.9 PVD38773.1 - 0.58 9.7 9.2 0.97 9.0 9.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Astacin PF01400.24 PVD38774.1 - 3.6e-62 209.4 1.1 6.4e-62 208.6 1.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 PVD38774.1 - 2e-56 190.4 20.1 3.9e-40 137.4 0.1 5.5 5 0 0 5 5 5 5 MAM domain, meprin/A5/mu Sushi PF00084.20 PVD38774.1 - 3.1e-10 40.5 0.9 1.1e-09 38.7 0.9 2.1 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Hexapep PF00132.24 PVD38775.1 - 9e-09 34.7 10.2 2.4e-05 23.9 4.1 4.5 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PVD38775.1 - 0.00026 20.7 1.7 0.012 15.3 0.3 3.6 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 PVD38775.1 - 0.018 14.0 3.6 0.14 11.0 0.2 2.0 1 1 1 2 2 2 0 L-fucokinase Ras PF00071.22 PVD38776.1 - 6e-38 130.0 0.2 7.7e-38 129.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD38776.1 - 5.4e-14 52.5 0.0 9.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PVD38776.1 - 3.9e-08 33.4 0.0 0.0042 17.0 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 PVD38776.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PVD38776.1 - 1.1e-06 28.3 0.1 3.2e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PVD38776.1 - 7.3e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 PVD38776.1 - 0.0033 16.8 0.1 0.44 9.9 0.0 2.4 3 0 0 3 3 3 1 Bacterial TniB protein ATP_bind_1 PF03029.17 PVD38776.1 - 0.004 17.0 0.0 1.5 8.5 0.1 2.3 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein G-alpha PF00503.20 PVD38776.1 - 0.0082 15.3 0.0 0.53 9.4 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 PVD38776.1 - 0.0098 16.3 0.1 0.021 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 PVD38776.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B Viral_helicase1 PF01443.18 PVD38776.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 PVD38776.1 - 0.078 12.2 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 PVD38776.1 - 0.086 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 PVD38776.1 - 0.092 12.0 0.1 0.3 10.3 0.0 1.9 2 1 0 2 2 2 0 Septin AAA_22 PF13401.6 PVD38776.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Glyco_hydro_18 PF00704.28 PVD38778.1 - 1.7e-22 80.6 0.0 2e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mucin2_WxxW PF13330.6 PVD38779.1 - 1.4e-18 67.5 0.6 2.4e-18 66.7 0.6 1.4 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region Vpu PF00558.19 PVD38780.1 - 0.00033 20.4 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Vpu protein SARAF PF06682.12 PVD38780.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Comm PF15957.5 PVD38780.1 - 0.03 14.6 0.0 6.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Commissureless FANCI_S1 PF14675.6 PVD38781.1 - 0.05 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 EF-hand_7 PF13499.6 PVD38782.1 - 7.2e-19 68.0 4.3 1e-09 38.7 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PVD38782.1 - 1.2e-17 62.1 2.8 0.0022 17.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PVD38782.1 - 4.8e-16 57.3 1.5 0.00046 19.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PVD38782.1 - 8.1e-12 44.8 5.1 2.8e-08 33.5 0.9 3.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 PVD38782.1 - 4.8e-08 33.2 0.1 0.005 17.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PVD38782.1 - 0.00031 20.1 1.4 1.1 8.9 0.0 3.6 4 0 0 4 4 4 2 EF hand SurA_N_2 PF13623.6 PVD38782.1 - 0.065 13.1 0.2 0.79 9.6 0.1 2.1 2 0 0 2 2 2 0 SurA N-terminal domain DREV PF05219.12 PVD38782.1 - 0.085 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Retrotrans_gag PF03732.17 PVD38782.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein EF-hand_1 PF00036.32 PVD38784.1 - 2.7e-38 126.7 11.6 8.1e-10 37.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PVD38784.1 - 2.9e-33 114.2 3.2 3.3e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PVD38784.1 - 2.5e-29 100.9 11.7 4.4e-13 48.9 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PVD38784.1 - 2.5e-28 95.6 7.6 1.6e-09 36.9 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PVD38784.1 - 3.5e-25 86.3 9.1 6.9e-07 28.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PVD38784.1 - 7.1e-15 55.1 0.1 7.9e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PVD38784.1 - 1.2e-06 28.4 0.4 0.014 15.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PVD38784.1 - 1.6e-06 28.4 0.0 0.009 16.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PVD38784.1 - 4.5e-05 23.4 0.0 0.083 12.9 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 PVD38784.1 - 0.00019 21.5 0.2 0.0015 18.6 0.0 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 PVD38784.1 - 0.0002 21.3 0.8 0.16 11.9 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 PVD38784.1 - 0.001 19.2 4.1 0.51 10.6 0.4 2.8 1 1 2 3 3 3 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 PVD38784.1 - 0.0012 19.2 0.3 0.66 10.3 0.1 2.6 2 1 1 3 3 3 1 RNA polymerase Rpb4 EF-hand_11 PF08976.11 PVD38784.1 - 0.0015 19.4 0.0 0.33 11.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain MotA_activ PF09114.10 PVD38784.1 - 0.0045 17.1 0.2 0.11 12.7 0.0 2.3 2 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF4497 PF14924.6 PVD38784.1 - 0.0051 17.3 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) dCache_2 PF08269.11 PVD38784.1 - 0.0053 16.0 0.0 0.31 10.2 0.0 2.2 1 1 1 2 2 2 1 Cache domain TerB PF05099.13 PVD38784.1 - 0.0082 16.1 0.4 0.069 13.1 0.1 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TerB Spore_III_AB PF09548.10 PVD38784.1 - 0.021 15.0 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SurA_N_2 PF13623.6 PVD38784.1 - 0.042 13.7 0.4 1.7 8.5 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 PVD38784.1 - 0.045 12.3 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 PVD38784.1 - 0.056 13.8 0.1 6.9 7.1 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain AAA_assoc_C PF09821.9 PVD38784.1 - 0.072 13.6 0.1 0.87 10.1 0.0 2.2 2 0 0 2 2 2 0 C-terminal AAA-associated domain MecA_N PF05223.11 PVD38784.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain p450 PF00067.22 PVD38785.1 - 8.7e-70 235.7 0.1 8.5e-69 232.5 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 PVD38786.1 - 4.1e-36 122.8 1.5 4.1e-17 61.9 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TIP_N PF12457.8 PVD38787.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal SAC3_GANP PF03399.16 PVD38788.1 - 2.7e-09 36.8 0.1 5.3e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP family DUF4604 PF15377.6 PVD38788.1 - 0.011 16.2 4.5 0.011 16.2 4.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) COX5A PF02284.16 PVD38788.1 - 0.04 13.9 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va RVT_1 PF00078.27 PVD38790.1 - 6.9e-23 81.3 0.0 1.1e-20 74.2 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cNMP_binding PF00027.29 PVD38791.1 - 6e-45 151.2 0.1 1.6e-21 76.1 0.0 2.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 PVD38791.1 - 0.043 13.5 7.8 0.69 9.7 0.1 2.8 2 1 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 PVD38791.1 - 0.56 9.9 3.4 0.88 9.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) 3Beta_HSD PF01073.19 PVD38792.1 - 2.4e-50 171.1 0.0 3e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PVD38792.1 - 1.9e-11 43.9 0.0 3.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PVD38792.1 - 3.4e-07 29.6 0.0 4.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PVD38792.1 - 3e-06 26.6 0.0 4.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 PVD38792.1 - 0.0056 15.8 0.1 0.0088 15.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 PVD38792.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SHIPPO-rpt PF07004.12 PVD38793.1 - 1e-13 51.5 18.9 0.00057 20.7 0.1 5.4 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat CXCR4_N PF12109.8 PVD38793.1 - 0.044 14.0 0.7 0.14 12.4 0.1 2.2 3 0 0 3 3 3 0 CXCR4 Chemokine receptor N terminal SHIPPO-rpt PF07004.12 PVD38794.1 - 1.7e-05 25.5 10.0 0.43 11.6 2.0 3.7 3 1 0 3 3 3 3 Sperm-tail PG-rich repeat IF3_N PF05198.16 PVD38798.1 - 0.17 12.2 0.0 2.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain UPA PF17217.3 PVD38801.1 - 3.4e-52 176.1 0.0 2.3e-51 173.4 0.0 2.0 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 PVD38801.1 - 2.1e-31 108.1 0.0 5.3e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 PVD38801.1 - 6.7e-17 61.4 0.1 1.3e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.19 PVD38801.1 - 5.9e-12 45.6 29.4 2.3e-11 43.8 9.2 2.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain I-set PF07679.16 PVD38801.1 - 1.9e-06 27.9 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 PVD38801.1 - 0.00012 22.4 0.1 0.00094 19.5 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 PVD38801.1 - 0.00028 21.4 0.0 0.0009 19.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 PVD38801.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 PVD38801.1 - 0.019 15.2 0.1 0.068 13.3 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain CcmD PF04995.14 PVD38801.1 - 0.053 13.6 0.5 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SKG6 PF08693.10 PVD38801.1 - 1.2 8.6 11.1 2.3 7.7 11.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CaMKII_AD PF08332.10 PVD38802.1 - 3.4e-38 130.7 0.0 6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase PF00069.25 PVD38802.1 - 1.2e-34 119.9 0.0 4e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38802.1 - 1.9e-11 43.7 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL_3 PF13474.6 PVD38802.1 - 0.0013 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 PVD38805.1 - 2.4e-14 53.0 24.4 2.4e-14 53.0 24.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily IlvC PF01450.19 PVD38805.1 - 0.23 11.7 0.0 0.38 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain BCLP PF12304.8 PVD38805.1 - 2.6 7.5 8.5 0.17 11.4 0.3 2.9 2 1 1 3 3 3 0 Beta-casein like protein HlyIII PF03006.20 PVD38806.1 - 4e-18 66.0 26.4 5.5e-18 65.5 26.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related MFS_1 PF07690.16 PVD38807.1 - 1.2e-06 27.7 4.0 1.2e-06 27.7 4.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PVD38807.1 - 0.00031 19.8 2.8 0.00031 19.8 2.8 2.3 2 1 0 3 3 3 1 Sugar (and other) transporter THUMP PF02926.17 PVD38808.1 - 9.9e-10 38.7 0.9 4.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 THUMP domain RRM_1 PF00076.22 PVD38809.1 - 1.7e-09 37.4 0.0 3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.11 PVD38810.1 - 2.4e-171 571.1 0.0 3.9e-171 570.4 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein Robl_LC7 PF03259.17 PVD38811.1 - 2.2e-15 56.2 0.1 2.6e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Profilin PF00235.19 PVD38811.1 - 0.03 14.6 0.1 0.036 14.3 0.1 1.4 1 1 0 1 1 1 0 Profilin AP_endonuc_2 PF01261.24 PVD38812.1 - 1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MAPKK1_Int PF08923.10 PVD38812.1 - 5.3e-26 90.8 0.3 1.4e-25 89.4 0.2 1.7 2 0 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting DUF2369 PF10179.9 PVD38814.1 - 7e-20 71.2 4.5 3.3e-15 56.2 0.1 3.9 4 1 1 5 5 5 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 PVD38814.1 - 1.8e-07 31.4 0.1 0.039 14.3 0.0 3.6 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PVD38814.1 - 9e-05 23.0 3.6 0.0024 18.4 0.2 2.9 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain TQ PF18202.1 PVD38814.1 - 0.048 14.2 0.4 0.37 11.3 0.1 2.4 2 0 0 2 2 2 0 T-Q ester bond containing domain DNA_pol_phi PF04931.13 PVD38815.1 - 0.0024 16.1 17.0 0.0025 16.0 17.0 1.0 1 0 0 1 1 1 1 DNA polymerase phi DUF2457 PF10446.9 PVD38815.1 - 0.0028 16.9 22.9 0.003 16.8 22.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 PVD38815.1 - 0.0028 17.4 20.2 0.0046 16.7 20.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PVD38815.1 - 0.019 14.3 23.6 0.022 14.1 23.6 1.1 1 0 0 1 1 1 0 NOA36 protein Slu7 PF11708.8 PVD38815.1 - 0.021 14.6 7.1 0.023 14.4 7.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RXT2_N PF08595.11 PVD38815.1 - 0.049 13.7 8.1 0.064 13.3 8.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Utp14 PF04615.13 PVD38815.1 - 0.07 11.7 6.8 0.068 11.7 6.8 1.2 1 0 0 1 1 1 0 Utp14 protein Voldacs PF03517.13 PVD38815.1 - 0.07 13.2 8.4 0.089 12.9 8.4 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Tom22 PF04281.13 PVD38815.1 - 0.14 11.9 5.7 0.2 11.5 5.7 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SDA1 PF05285.12 PVD38815.1 - 0.25 10.7 13.4 0.32 10.4 13.4 1.1 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 PVD38815.1 - 0.42 9.4 1.3 0.48 9.2 1.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_3_Rpc31 PF11705.8 PVD38815.1 - 0.64 10.2 18.5 0.76 10.0 18.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 PVD38815.1 - 0.64 8.5 12.9 0.71 8.3 12.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 PVD38815.1 - 0.8 9.4 6.4 0.92 9.2 6.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2796 PF10986.8 PVD38815.1 - 0.86 9.6 6.4 1 9.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) GCIP PF13324.6 PVD38815.1 - 1.1 8.8 12.8 1.3 8.6 12.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3295 PF11702.8 PVD38815.1 - 1.2 8.4 15.3 1.4 8.2 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) BUD22 PF09073.10 PVD38815.1 - 1.6 8.0 13.6 1.8 7.8 13.6 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 PVD38815.1 - 2.5 8.0 17.8 2.8 7.9 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 PVD38815.1 - 2.6 6.2 16.4 3.3 5.9 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 PVD38815.1 - 5.8 6.4 18.3 6.9 6.2 18.3 1.1 1 0 0 1 1 1 0 PPP4R2 SGT1 PF07093.11 PVD38815.1 - 6.9 5.0 10.0 7.8 4.8 10.0 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 PVD38815.1 - 7.2 4.7 19.0 8.5 4.4 19.0 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 PVD38815.1 - 9.1 6.3 17.4 13 5.8 17.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein AAA PF00004.29 PVD38816.1 - 2.5e-08 34.4 0.1 1.6e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PVD38816.1 - 9.6e-08 32.2 0.3 4.6e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 PVD38816.1 - 0.00014 22.3 0.1 0.00044 20.7 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PVD38816.1 - 0.00026 21.3 0.8 0.0026 18.0 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 PVD38816.1 - 0.001 19.1 0.0 0.4 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PVD38816.1 - 0.0068 16.6 0.5 0.038 14.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 PVD38816.1 - 0.0071 16.7 0.0 0.037 14.4 0.0 2.3 1 0 0 1 1 1 1 AAA C-terminal domain RNA_helicase PF00910.22 PVD38816.1 - 0.015 15.7 1.0 0.79 10.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 PVD38816.1 - 0.032 14.2 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PVD38816.1 - 0.039 14.5 1.9 0.17 12.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 PVD38816.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 PVD38816.1 - 0.08 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 PVD38816.1 - 0.093 13.0 0.3 0.28 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 PVD38816.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Sec23_trunk PF04811.15 PVD38817.1 - 7.9e-81 271.2 0.0 1.2e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PVD38817.1 - 3.8e-27 94.1 0.0 7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 PVD38817.1 - 8.6e-18 64.9 0.1 1.8e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 PVD38817.1 - 2.7e-09 36.8 0.0 6.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Glyco_transf_10 PF00852.19 PVD38818.1 - 2.5e-36 125.0 0.4 4.2e-36 124.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD38818.1 - 3.1e-10 40.5 0.1 1.6e-09 38.2 0.0 2.1 1 1 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 PVD38818.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Dus PF01207.17 PVD38819.1 - 6.6e-76 255.4 0.1 1.7e-75 254.0 0.0 1.6 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PVD38819.1 - 0.00016 21.2 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_S14 PF00253.21 PVD38819.1 - 0.00039 20.1 0.6 0.0008 19.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e NMO PF03060.15 PVD38819.1 - 0.00051 19.5 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 PVD38819.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 PVD38819.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 PVD38819.1 - 0.017 14.3 0.0 0.058 12.6 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase SOR_SNZ PF01680.17 PVD38819.1 - 0.021 14.6 0.5 0.063 13.1 0.0 1.9 2 1 1 3 3 3 0 SOR/SNZ family FapA PF03961.13 PVD38819.1 - 0.22 10.1 0.3 0.4 9.2 0.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNA_pol_Rpb1_1 PF04997.12 PVD38820.1 - 2.3e-90 303.1 1.1 3.7e-90 302.4 1.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 PVD38820.1 - 1.6e-82 276.9 1.2 3.5e-82 275.8 1.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PVD38820.1 - 3e-66 222.7 0.2 7.4e-66 221.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PVD38820.1 - 6.3e-41 139.9 0.0 4.7e-40 137.1 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PVD38820.1 - 8.4e-31 106.1 0.0 2.7e-30 104.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 UNC45-central PF11701.8 PVD38820.1 - 0.13 12.2 0.1 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central TRAPPC-Trs85 PF12739.7 PVD38820.1 - 0.14 11.1 0.3 0.43 9.5 0.2 1.7 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DuoxA PF10204.9 PVD38821.1 - 1.3e-108 362.2 8.4 1.6e-108 362.0 8.4 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor CDC45 PF02724.14 PVD38821.1 - 0.044 12.1 0.0 0.055 11.8 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Phlebovirus_G2 PF07245.11 PVD38821.1 - 0.87 8.0 2.1 1.3 7.4 2.1 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 YqzH PF14164.6 PVD38822.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 3 0 0 3 3 3 0 YqzH-like protein fn3_4 PF16794.5 PVD38823.1 - 5.2e-37 125.9 0.0 1e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain Jnk-SapK_ap_N PF09744.9 PVD38823.1 - 0.063 13.5 5.1 0.099 12.9 5.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Lipase_chap PF03280.14 PVD38823.1 - 0.19 11.6 2.6 0.32 10.9 2.6 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Vps35 PF03635.17 PVD38824.1 - 0.00027 19.6 3.9 0.058 11.9 0.8 2.8 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 35 TPR_15 PF13429.6 PVD38824.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PAH PF02671.21 PVD38824.1 - 5.4 7.3 5.9 26 5.0 0.3 3.4 4 0 0 4 4 4 0 Paired amphipathic helix repeat Gemin6 PF06372.12 PVD38825.1 - 1.5e-39 135.3 0.1 1.7e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 PVD38825.1 - 0.0065 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Rv2175c_C PF18367.1 PVD38825.1 - 0.11 12.6 0.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Rv2175c C-terminal domain of unknown function DUF4564 PF15169.6 PVD38826.1 - 1.3e-35 122.8 0.0 1.5e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) DUF4443 PF14544.6 PVD38826.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Tmem26 PF09772.9 PVD38827.1 - 7.8e-22 78.0 0.9 8.9e-22 77.8 0.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 Prokineticin PF06607.11 PVD38828.1 - 0.43 10.9 11.8 1 9.7 11.8 1.8 1 1 0 1 1 1 0 Prokineticin DUF4485 PF14846.6 PVD38829.1 - 5.3e-28 96.9 3.0 1.1e-27 95.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4485) Death_2 PF14786.6 PVD38829.1 - 0.8 9.6 7.3 2.1 8.3 0.4 2.8 2 0 0 2 2 2 0 Tube Death domain Njmu-R1 PF15053.6 PVD38830.1 - 5.6e-40 137.5 2.0 1.1e-30 107.0 0.3 2.0 2 0 0 2 2 2 2 Mjmu-R1-like protein family REPA_OB_2 PF16900.5 PVD38831.1 - 1.6e-08 34.4 0.5 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 2 Replication protein A OB domain S-AdoMet_synt_M PF02772.16 PVD38832.1 - 1.4e-46 157.6 0.2 3.1e-46 156.5 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PVD38832.1 - 2.5e-44 150.0 0.9 3.5e-44 149.5 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.16 PVD38832.1 - 2e-26 92.6 0.1 3.9e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain AdoMet_Synthase PF01941.19 PVD38832.1 - 0.01 14.6 0.9 0.098 11.4 0.2 2.1 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) EF-hand_7 PF13499.6 PVD38833.1 - 4.4e-27 94.3 26.1 8.5e-11 42.1 0.7 5.7 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 PVD38833.1 - 1.2e-23 82.7 13.3 1.6e-06 27.9 0.0 5.6 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 PVD38833.1 - 2.6e-20 70.4 8.2 6.1e-07 28.5 0.0 7.2 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.6 PVD38833.1 - 1.4e-19 68.3 8.7 8.5e-07 28.4 0.0 7.4 6 1 0 7 7 7 4 EF-hand domain EF-hand_11 PF08976.11 PVD38833.1 - 1.1e-16 61.6 5.1 1.1e-06 29.5 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 PVD38833.1 - 4.2e-06 26.0 7.1 2.1e-05 23.8 0.0 5.0 6 0 0 6 6 6 1 EF hand DUF5580 PF17743.1 PVD38833.1 - 0.05 12.2 0.7 1.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5580) EF-hand_9 PF14658.6 PVD38833.1 - 0.058 13.7 0.0 19 5.7 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 PVD38833.1 - 0.1 12.5 1.3 1.6 8.6 0.1 2.9 2 0 0 2 2 2 0 EF hand NADPH_Ox PF08414.10 PVD38833.1 - 0.54 10.6 3.5 3 8.3 0.0 3.6 4 0 0 4 4 4 0 Respiratory burst NADPH oxidase SPARC_Ca_bdg PF10591.9 PVD38833.1 - 2.5 8.5 8.4 19 5.6 0.0 3.9 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 PVD38834.1 - 0.00029 20.6 0.1 0.23 11.3 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 PVD38834.1 - 0.55 10.7 2.3 17 5.9 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain pair UCH PF00443.29 PVD38835.1 - 3.9e-28 98.6 0.1 5.2e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Piwi PF02171.17 PVD38836.1 - 1.1e-84 284.2 0.0 2e-84 283.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 PVD38836.1 - 2.6e-30 105.0 0.0 5.4e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PVD38836.1 - 0.00075 19.1 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PVD38836.1 - 0.0029 18.2 0.0 0.0069 17.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ParA PF10609.9 PVD38837.1 - 2.1e-97 325.4 0.4 2.5e-97 325.2 0.4 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PVD38837.1 - 5.2e-14 52.4 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PVD38837.1 - 8.7e-07 29.0 0.3 3e-06 27.3 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PVD38837.1 - 3.9e-05 23.3 0.3 7.6e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 PVD38837.1 - 0.0003 20.1 0.4 0.0031 16.7 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 PVD38837.1 - 0.00035 19.9 0.1 0.0005 19.5 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 PVD38837.1 - 0.0019 17.7 0.0 0.055 12.9 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 PVD38837.1 - 0.0033 17.3 0.1 0.1 12.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF1610 PF07754.11 PVD38837.1 - 0.014 15.4 0.5 0.047 13.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) VirC1 PF07015.11 PVD38837.1 - 0.18 11.1 0.0 0.44 9.8 0.0 1.6 2 0 0 2 2 2 0 VirC1 protein DUF2678 PF10856.8 PVD38838.1 - 0.00032 20.6 6.9 0.00046 20.1 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) 7TMR-DISM_7TM PF07695.11 PVD38838.1 - 0.093 12.6 9.8 0.23 11.3 8.5 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling WBP-1 PF11669.8 PVD38838.1 - 0.15 12.7 0.8 0.57 10.9 0.0 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF2678 PF10856.8 PVD38839.1 - 0.00093 19.1 2.6 0.0011 18.9 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Ceramidase PF05875.12 PVD38839.1 - 0.08 12.4 2.4 0.15 11.4 2.4 1.4 1 1 1 2 2 2 0 Ceramidase DUF2207 PF09972.9 PVD38839.1 - 1.3 7.7 3.5 1.3 7.7 3.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PEP-CTERM PF07589.11 PVD38839.1 - 2.6 8.3 4.4 1.1 9.4 1.6 1.9 2 0 0 2 2 2 0 PEP-CTERM motif TGF_beta PF00019.20 PVD38840.1 - 3.2e-24 85.9 0.1 5.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 PVD38840.1 - 1.7e-05 24.7 0.1 2.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Stb3 PF10330.9 PVD38840.1 - 0.29 11.2 2.1 0.68 10.0 0.2 2.3 2 0 0 2 2 2 0 Putative Sin3 binding protein LRR_8 PF13855.6 PVD38841.1 - 3.6e-47 158.0 55.5 5.9e-07 29.2 1.0 9.3 5 2 4 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 PVD38841.1 - 1.8e-29 101.2 62.9 3.2e-06 27.4 2.3 10.7 4 2 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD38841.1 - 6.4e-07 29.0 23.1 0.084 12.4 4.7 5.7 2 2 4 6 6 6 4 Leucine-rich repeat LRR_5 PF13306.6 PVD38841.1 - 1.5e-05 24.9 3.5 0.27 11.2 0.0 3.9 3 2 2 5 5 5 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD38841.1 - 2.8e-05 24.1 63.7 0.37 11.5 0.1 14.7 15 1 1 16 16 16 5 Leucine Rich Repeat IMD PF08397.11 PVD38842.1 - 1.4e-24 86.7 0.8 2.1e-24 86.2 0.8 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 PVD38842.1 - 9.4e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PVD38842.1 - 4.3e-07 29.4 0.0 6.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PVD38842.1 - 3.3e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 PVD38842.1 - 0.015 14.9 1.2 0.024 14.3 1.2 1.2 1 0 0 1 1 1 0 BAR domain UN_NPL4 PF11543.8 PVD38843.1 - 0.51 10.9 3.1 61 4.2 0.0 3.8 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 CHCH PF06747.13 PVD38844.1 - 7.7e-08 32.3 9.6 1.2e-07 31.7 9.6 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 PVD38844.1 - 0.0046 16.6 5.7 0.0067 16.1 5.3 1.5 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 PVD38844.1 - 0.0092 16.0 6.5 0.02 14.9 6.5 1.6 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 PVD38844.1 - 0.25 11.7 0.6 0.25 11.7 0.6 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 PVD38844.1 - 0.38 10.8 9.6 1.4 9.0 10.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Lactamase_B_6 PF16661.5 PVD38845.1 - 7.7e-12 45.0 0.0 1.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PVD38845.1 - 9e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 PVD38845.1 - 0.0032 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family Beach PF02138.18 PVD38846.1 - 1.3e-122 408.5 0.2 2.3e-122 407.7 0.2 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4800 PF16057.5 PVD38846.1 - 1.3e-92 309.7 8.1 2.1e-92 309.0 8.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF4704 PF15787.5 PVD38846.1 - 3.1e-35 121.8 11.0 9.3e-35 120.2 0.4 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4704) WD40 PF00400.32 PVD38846.1 - 2.2e-07 31.5 7.2 0.0015 19.3 0.5 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 PVD38846.1 - 0.0037 17.4 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NDK PF00334.19 PVD38847.1 - 3.3e-200 655.2 2.2 8.9e-37 126.1 0.0 7.3 4 3 3 7 7 7 7 Nucleoside diphosphate kinase Thioredoxin PF00085.20 PVD38847.1 - 8.8e-16 57.8 0.2 6e-08 32.6 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin IQCJ-SCHIP1 PF15157.6 PVD38847.1 - 0.0064 16.4 0.0 2 8.2 0.0 3.4 3 0 0 3 3 3 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif AhpC-TSA PF00578.21 PVD38847.1 - 0.0081 16.1 0.2 2.4 8.1 0.0 2.8 2 0 0 2 2 2 1 AhpC/TSA family DUF3964 PF13107.6 PVD38847.1 - 0.012 16.0 0.5 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) Ala_racemase_N PF01168.20 PVD38847.1 - 0.055 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain DUF4898 PF16239.5 PVD38847.1 - 0.099 12.6 5.7 5.7 7.0 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4898) DUF1269 PF06897.12 PVD38847.1 - 0.11 12.8 0.0 17 5.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1269) IlvN PF07991.12 PVD38847.1 - 0.12 12.0 2.1 4.2 6.9 0.1 2.9 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RsfS PF02410.15 PVD38847.1 - 0.17 12.3 0.6 0.64 10.5 0.6 2.0 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation Vps8 PF12816.7 PVD38848.1 - 4.9e-44 150.2 8.9 4.7e-36 124.2 0.2 4.2 3 2 2 5 5 5 2 Golgi CORVET complex core vacuolar protein 8 zf-RING_UBOX PF13445.6 PVD38848.1 - 0.0016 18.4 3.9 0.0047 16.9 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PVD38848.1 - 0.0022 17.9 4.6 0.0062 16.5 4.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Clathrin PF00637.20 PVD38848.1 - 0.011 15.6 8.2 0.19 11.6 0.8 3.9 3 1 1 4 4 4 0 Region in Clathrin and VPS zf-RING_2 PF13639.6 PVD38848.1 - 0.02 15.2 5.1 0.066 13.5 5.1 2.0 1 0 0 1 1 1 0 Ring finger domain DUF5049 PF16468.5 PVD38848.1 - 0.027 14.4 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) zf-RING_11 PF17123.5 PVD38848.1 - 0.043 13.6 2.9 0.14 11.9 2.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 PVD38848.1 - 0.064 13.2 1.0 0.15 12.0 1.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 PVD38848.1 - 0.077 13.1 1.1 0.18 11.9 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 PVD38848.1 - 0.51 10.3 3.2 1.1 9.2 3.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 PVD38848.1 - 0.92 9.4 4.5 2.5 8.1 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C14 PF00656.22 PVD38849.1 - 1.5e-20 74.3 0.0 5.7e-12 46.1 0.0 2.3 1 1 1 2 2 2 2 Caspase domain DED PF01335.21 PVD38849.1 - 2.9e-15 56.3 0.4 5.6e-15 55.4 0.4 1.5 1 0 0 1 1 1 1 Death effector domain MCRS_N PF13325.6 PVD38850.1 - 1.7e-83 279.5 1.1 2.6e-83 279.0 1.1 1.3 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.26 PVD38850.1 - 0.00011 22.5 0.1 0.00024 21.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.25 PVD38851.1 - 7e-51 173.1 0.0 8.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38851.1 - 5.3e-23 81.6 0.0 8.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 PVD38851.1 - 7.8e-17 61.1 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 PVD38851.1 - 1.9e-14 54.0 0.1 3.6e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 PVD38851.1 - 2.4e-13 50.2 0.1 4.6e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.25 PVD38851.1 - 3.6e-09 36.7 0.0 6.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 PVD38851.1 - 2e-06 28.1 0.1 3.6e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 PVD38851.1 - 6.8e-06 26.2 0.2 0.11 12.6 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin V-set domain RIO1 PF01163.22 PVD38851.1 - 2.1e-05 24.2 0.0 6.6e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 PVD38851.1 - 0.00013 21.4 0.7 0.00021 20.7 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C2-set_2 PF08205.12 PVD38851.1 - 0.0051 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain APH PF01636.23 PVD38851.1 - 0.065 13.1 0.4 0.16 11.9 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.20 PVD38852.1 - 5.1e-73 245.2 5.5 1.8e-37 129.3 0.5 5.1 6 1 0 7 7 7 2 RhoGEF domain Spectrin PF00435.21 PVD38852.1 - 2e-44 150.3 64.7 2.5e-10 40.8 3.1 10.0 9 1 1 10 10 10 7 Spectrin repeat PH PF00169.29 PVD38852.1 - 1.3e-11 44.9 0.5 8.4e-05 23.0 0.0 3.0 2 0 0 2 2 2 2 PH domain PH_10 PF15411.6 PVD38852.1 - 1.4e-09 38.2 0.3 0.00026 21.2 0.1 3.3 2 0 0 2 2 2 2 Pleckstrin homology domain CRAL_TRIO_2 PF13716.6 PVD38852.1 - 4.5e-08 33.3 0.0 3.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain IQ_SEC7_PH PF16453.5 PVD38852.1 - 2.5e-07 30.7 2.5 0.016 15.2 0.0 3.6 3 0 0 3 3 3 2 PH domain CRAL_TRIO PF00650.20 PVD38852.1 - 5.7e-06 26.1 0.0 2.2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain SH3-RhoG_link PF16609.5 PVD38852.1 - 1.5e-05 24.9 12.6 1.5e-05 24.9 12.6 3.8 3 1 0 3 3 3 1 SH3-RhoGEF linking unstructured region SH3_2 PF07653.17 PVD38852.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_13 PF16652.5 PVD38852.1 - 0.0085 15.9 0.7 1.2 9.0 0.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain Orbi_VP6 PF01516.16 PVD38852.1 - 0.27 10.7 3.1 0.59 9.6 3.1 1.5 1 0 0 1 1 1 0 Orbivirus helicase VP6 Synaptobrevin PF00957.21 PVD38852.1 - 0.31 10.8 2.7 2.3 8.1 0.1 3.6 4 0 0 4 4 4 0 Synaptobrevin OST-HTH PF12872.7 PVD38853.1 - 7.5e-42 141.0 0.0 2.8e-09 36.7 0.0 7.6 9 0 0 9 9 9 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.8 PVD38853.1 - 2.7e-20 72.2 0.1 1.4e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 NYN PF01936.18 PVD38853.1 - 9.1e-15 55.4 1.3 7.6e-14 52.4 0.2 2.8 3 0 0 3 3 3 1 NYN domain RRM_1 PF00076.22 PVD38853.1 - 1.3e-05 25.0 0.0 0.018 14.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIN_4 PF13638.6 PVD38853.1 - 0.062 13.6 0.3 0.21 11.9 0.3 1.9 1 0 0 1 1 1 0 PIN domain Urease_gamma PF00547.18 PVD38853.1 - 0.24 11.7 0.8 1.3 9.4 0.1 2.5 3 0 0 3 3 3 0 Urease, gamma subunit Pkinase PF00069.25 PVD38854.1 - 1.4e-68 231.2 0.0 1.7e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD38854.1 - 7.9e-36 123.7 0.0 1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD38854.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD38854.1 - 0.0016 18.4 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PVD38854.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 cNMP_binding PF00027.29 PVD38854.1 - 0.054 13.6 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain FTA2 PF13095.6 PVD38854.1 - 0.084 12.5 0.1 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 cNMP_binding PF00027.29 PVD38855.1 - 1.7e-17 63.2 0.0 3.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Fez1 PF06818.15 PVD38855.1 - 0.015 15.8 1.5 0.015 15.8 1.5 2.0 2 0 0 2 2 2 0 Fez1 HAP1_N PF04849.13 PVD38855.1 - 0.056 12.6 5.2 0.042 13.1 3.0 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Spc7 PF08317.11 PVD38855.1 - 0.094 11.6 3.8 0.17 10.7 3.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 PVD38855.1 - 0.11 13.2 1.9 0.26 11.9 0.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Spc29 PF17082.5 PVD38855.1 - 0.11 12.3 1.4 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Spindle Pole Component 29 USP8_interact PF08941.10 PVD38855.1 - 0.13 12.1 2.4 0.47 10.3 2.5 1.8 1 1 1 2 2 2 0 USP8 interacting PKcGMP_CC PF16808.5 PVD38855.1 - 0.23 11.3 10.7 9.1 6.2 7.2 3.6 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 PVD38855.1 - 0.35 11.1 6.0 0.86 9.8 6.0 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 PVD38855.1 - 0.4 10.5 4.2 1.3 8.8 4.2 1.9 1 0 0 1 1 1 0 Septum formation initiator FAM76 PF16046.5 PVD38855.1 - 0.98 8.7 4.4 0.26 10.6 1.2 1.6 2 0 0 2 2 2 0 FAM76 protein UPF0242 PF06785.11 PVD38855.1 - 1.2 9.2 5.6 0.53 10.4 2.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 PVD38855.1 - 1.3 9.1 8.9 3.9 7.5 7.0 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MPS2 PF17060.5 PVD38855.1 - 3.6 6.7 6.7 1.2 8.4 3.4 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 LRR_4 PF12799.7 PVD38857.1 - 1.6e-10 41.0 11.6 0.12 12.8 0.0 5.7 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD38857.1 - 4.5e-10 39.1 17.4 0.0044 16.8 0.0 6.1 3 2 3 6 6 6 5 Leucine rich repeat LRR_6 PF13516.6 PVD38857.1 - 3.3e-07 29.8 17.3 2.1 8.6 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 PVD38857.1 - 0.0031 17.8 16.0 3.4 8.6 0.1 7.2 6 1 0 6 6 6 1 Leucine Rich Repeat dbPDZ_assoc PF16610.5 PVD38858.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 zf-AD PF07776.15 PVD38858.1 - 0.18 12.1 2.0 0.36 11.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF948 PF06103.11 PVD38858.1 - 0.29 11.4 12.6 0.81 10.0 1.5 4.0 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) T3SSipB PF16535.5 PVD38858.1 - 0.47 10.9 24.9 1.5 9.3 11.8 3.2 3 0 0 3 3 3 0 Type III cell invasion protein SipB YfhO PF09586.10 PVD38858.1 - 0.6 8.3 13.7 0.88 7.7 13.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Laminin_II PF06009.12 PVD38858.1 - 1.6 8.8 32.3 0.022 14.8 13.0 4.3 2 2 1 4 4 4 0 Laminin Domain II HXXSHH PF07586.11 PVD38858.1 - 2.6 7.5 13.0 3.1 7.3 8.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1552) PEP-utilisers_N PF05524.13 PVD38858.1 - 2.9 8.1 12.7 1.8 8.7 1.5 3.5 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal Allexi_40kDa PF05549.11 PVD38858.1 - 3.6 7.0 24.7 0.18 11.3 10.1 3.2 1 1 2 3 3 3 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 PVD38858.1 - 5.9 7.4 18.4 3 8.3 1.9 4.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Voltage_CLC PF00654.20 PVD38860.1 - 2.2e-96 323.2 23.1 2.8e-95 319.6 22.0 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PVD38860.1 - 0.00049 20.5 0.2 0.0017 18.8 0.0 2.0 2 0 0 2 2 2 1 CBS domain Stomagen PF16851.5 PVD38860.1 - 0.00073 19.5 1.5 0.0016 18.4 1.5 1.6 1 0 0 1 1 1 1 Stomagen DUF1201 PF06716.11 PVD38860.1 - 0.19 11.8 1.5 0.52 10.4 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) GtrA PF04138.14 PVD38860.1 - 9 6.6 13.3 0.098 12.9 0.7 3.7 4 0 0 4 4 4 0 GtrA-like protein RasGEF PF00617.19 PVD38861.1 - 3e-40 138.3 1.5 8.1e-40 136.9 0.6 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PVD38861.1 - 8.3e-12 45.3 1.8 2e-10 40.9 0.3 3.2 2 1 0 2 2 2 1 RasGEF N-terminal motif PDZ PF00595.24 PVD38861.1 - 1.9e-11 44.1 0.0 3.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD38861.1 - 6e-10 38.8 0.0 4.8e-09 35.9 0.0 2.3 1 1 1 2 2 2 1 PDZ domain RA PF00788.23 PVD38861.1 - 6.6e-09 36.3 0.1 1.9e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 PVD38861.1 - 6.9e-08 32.5 0.2 2.8e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 PVD38861.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SLY PF12485.8 PVD38861.1 - 0.02 15.6 1.4 0.083 13.6 1.4 2.0 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF5470 PF17564.2 PVD38861.1 - 4.7 7.5 5.3 13 6.1 5.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5470) SHMT PF00464.19 PVD38863.1 - 4.2e-200 664.4 0.0 6.6e-200 663.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Cluap1 PF10234.9 PVD38863.1 - 3e-115 384.3 9.9 7.1e-115 383.0 9.9 1.7 1 0 0 1 1 1 1 Clusterin-associated protein-1 LIF_OSM PF01291.17 PVD38863.1 - 0.028 14.6 0.9 0.054 13.6 0.0 1.8 2 0 0 2 2 2 0 LIF / OSM family UreE_N PF02814.15 PVD38863.1 - 0.087 12.4 0.2 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Nif11 PF07862.11 PVD38863.1 - 0.16 12.3 1.2 1.8 8.9 0.2 3.2 3 0 0 3 3 3 0 Nif11 domain ERO1 PF04137.15 PVD38863.1 - 0.41 9.8 4.2 0.76 8.9 4.2 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) V_ATPase_I PF01496.19 PVD38863.1 - 1.1 7.0 8.7 1.7 6.5 8.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 PVD38863.1 - 2.4 7.7 10.1 5.1 6.6 10.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 PVD38863.1 - 6.8 7.1 21.0 7.5 6.9 19.1 2.1 2 1 0 2 2 2 0 Fez1 Ribosomal_L12 PF00542.19 PVD38864.1 - 2.3e-20 72.7 6.0 2.3e-20 72.7 6.0 2.9 2 1 1 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 PVD38864.1 - 2.1e-11 43.3 1.1 2.1e-11 43.3 1.1 2.7 2 2 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Tma16 PF11176.8 PVD38865.1 - 2.2e-35 121.7 6.3 2.7e-35 121.4 6.3 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 ChaC PF04752.12 PVD38865.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 ChaC-like protein PCNA_C PF02747.15 PVD38866.1 - 4.5e-63 211.1 0.2 9.1e-63 210.2 0.1 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 PVD38866.1 - 2.4e-57 192.1 1.0 3e-57 191.8 0.3 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 PVD38866.1 - 6.5e-07 28.7 0.2 0.00039 19.6 0.1 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 PVD38866.1 - 6.9e-07 29.0 0.1 8.5e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 EF-hand_8 PF13833.6 PVD38867.1 - 1.9e-13 50.0 8.1 5.9e-09 35.6 0.2 4.5 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD38867.1 - 1.1e-11 43.7 11.9 0.00026 20.7 0.1 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 PVD38867.1 - 4.9e-11 41.4 23.7 1.9e-05 23.8 0.3 6.5 7 0 0 7 7 7 2 EF hand EF-hand_7 PF13499.6 PVD38867.1 - 1.1e-07 32.2 13.8 0.061 13.8 9.6 4.5 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD38867.1 - 1.7e-06 27.3 19.2 5.2e-05 22.6 1.1 4.7 5 0 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 PVD38867.1 - 7e-05 22.7 0.9 0.62 10.0 0.3 2.9 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 PVD38867.1 - 0.045 14.1 0.1 7.2 7.0 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain DAG_kinase_N PF14513.6 PVD38867.1 - 0.077 13.2 0.6 0.91 9.7 0.0 2.7 2 1 1 3 3 3 0 Diacylglycerol kinase N-terminus SPARC_Ca_bdg PF10591.9 PVD38867.1 - 0.26 11.6 3.9 6.6 7.1 0.2 3.6 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RRM_1 PF00076.22 PVD38868.1 - 4.8e-17 61.6 0.1 4e-09 36.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 PVD38868.1 - 0.081 13.1 0.0 25 5.0 0.0 3.2 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 PVD38869.1 - 1.7e-15 56.6 0.0 8.7e-06 25.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mob1_phocein PF03637.17 PVD38870.1 - 1.7e-83 278.8 0.2 2.1e-83 278.4 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Abhydro_lipase PF04083.16 PVD38871.1 - 2.9e-21 74.8 0.0 9.4e-21 73.2 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 PVD38871.1 - 7.5e-20 71.7 0.1 4.7e-19 69.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PVD38871.1 - 1.1e-07 31.4 0.0 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PVD38871.1 - 0.0011 19.7 0.1 0.0014 19.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 PVD38871.1 - 0.022 14.4 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 PVD38871.1 - 0.07 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 PVD38871.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Histone PF00125.24 PVD38872.1 - 5.4e-19 68.8 0.0 6.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PVD38872.1 - 1.3e-13 50.5 0.4 2.4e-13 49.6 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PVD38872.1 - 0.01 16.1 0.1 0.018 15.3 0.0 1.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RTP801_C PF07809.11 PVD38873.1 - 1.4e-29 102.4 0.1 2.7e-29 101.5 0.1 1.5 1 0 0 1 1 1 1 RTP801 C-terminal region Collagen PF01391.18 PVD38874.1 - 2.7e-27 94.3 106.8 1.2e-09 37.8 32.8 4.5 3 2 1 4 4 4 4 Collagen triple helix repeat (20 copies) zf-RING_UBOX PF13445.6 PVD38876.1 - 1.5e-09 37.7 7.8 1.5e-09 37.7 7.8 2.5 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PVD38876.1 - 2e-09 37.2 7.8 2e-09 37.2 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD38876.1 - 2.3e-09 37.0 5.2 2.3e-09 37.0 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD38876.1 - 6.9e-07 29.5 8.1 6.9e-07 29.5 8.1 2.5 2 0 0 2 2 1 1 Ring finger domain zf-B_box PF00643.24 PVD38876.1 - 9.1e-07 28.9 8.3 9.1e-07 28.9 8.3 3.1 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.6 PVD38876.1 - 1.5e-06 28.0 6.7 1.5e-06 28.0 6.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD38876.1 - 7.5e-06 25.7 6.6 7.5e-06 25.7 6.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PVD38876.1 - 1e-05 25.3 8.4 1e-05 25.3 8.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD38876.1 - 0.00097 19.3 11.3 0.00097 19.3 11.3 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 PVD38876.1 - 1.8 8.8 10.4 4.4 7.6 0.9 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_11 PF17123.5 PVD38876.1 - 8.5 6.2 11.6 0.14 12.0 4.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger C1q PF00386.21 PVD38877.1 - 1.9e-18 66.9 0.7 2.2e-18 66.7 0.1 1.5 2 0 0 2 2 2 1 C1q domain SlyX PF04102.12 PVD38877.1 - 0.0013 19.3 4.6 0.0025 18.4 4.6 1.5 1 0 0 1 1 1 1 SlyX PA14 PF07691.12 PVD38877.1 - 0.019 14.8 0.3 0.56 10.0 0.0 2.6 3 0 0 3 3 3 0 PA14 domain Cep57_CLD_2 PF14197.6 PVD38877.1 - 0.12 12.5 0.3 0.12 12.5 0.3 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TEX13 PF15186.6 PVD38877.1 - 0.47 10.1 4.0 1 9.0 2.5 2.0 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family RhoGEF PF00621.20 PVD38880.1 - 7.1e-41 140.4 3.8 1e-40 139.9 3.8 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 PVD38880.1 - 0.00015 21.6 0.2 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 PVD38880.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 PVD38880.1 - 0.016 15.6 0.2 0.046 14.1 0.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain EGF PF00008.27 PVD38881.1 - 2.6e-10 40.4 40.1 1e-07 32.1 5.6 16.5 17 0 0 17 17 17 7 EGF-like domain VWD PF00094.25 PVD38881.1 - 1.9e-09 38.0 0.0 5.9e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 PVD38881.1 - 3.1e-06 27.5 235.0 0.0028 18.0 8.3 16.2 16 0 0 16 16 16 9 EGF-like domain hEGF PF12661.7 PVD38881.1 - 3.4e-06 27.5 181.3 5.2e-05 23.7 4.3 15.7 15 1 0 15 15 15 9 Human growth factor-like EGF DUF4670 PF15709.5 PVD38884.1 - 1.8e-22 80.4 138.1 7.4e-22 78.4 138.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4670) fn3 PF00041.21 PVD38885.1 - 1.1e-08 35.2 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 PVD38885.1 - 3.1e-07 30.8 0.3 1.9e-06 28.3 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) RA PF00788.23 PVD38885.1 - 1.2e-06 29.1 0.0 4.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ank_2 PF12796.7 PVD38885.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CCG PF02754.16 PVD38885.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich domain Ank_5 PF13857.6 PVD38885.1 - 0.14 12.5 0.2 1.5 9.3 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38885.1 - 0.26 12.0 1.5 16 6.5 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat FBPase PF00316.20 PVD38888.1 - 1e-74 250.1 0.3 1.5e-74 249.5 0.3 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Ependymin PF00811.18 PVD38888.1 - 1e-13 51.6 0.0 2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ependymin Inositol_P PF00459.25 PVD38888.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family DUF4457 PF14652.6 PVD38889.1 - 2.3e-199 661.4 0.0 5.5e-137 456.4 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 PVD38889.1 - 0.00013 21.9 0.1 0.67 10.0 0.0 4.9 6 0 0 6 6 6 2 Sad1 / UNC-like C-terminal COX6B PF02297.17 PVD38890.1 - 1.3e-15 57.4 8.5 2.9e-15 56.2 8.5 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb MFS_2 PF13347.6 PVD38890.1 - 5.6e-11 41.6 3.1 4.7e-10 38.6 3.1 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_2 PF13347.6 PVD38891.1 - 0.00012 20.7 0.0 0.00013 20.6 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Thioredox_DsbH PF03190.15 PVD38892.1 - 1.3e-60 204.0 0.0 2.3e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PVD38892.1 - 4e-09 36.5 0.0 8.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 PVD38892.1 - 0.0073 15.4 0.1 0.059 12.4 0.0 2.2 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.6 PVD38892.1 - 0.071 13.6 0.1 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain C5-epim_C PF06662.13 PVD38892.1 - 0.098 12.2 0.1 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sp38 PF07354.12 PVD38892.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) CAP_N PF01213.19 PVD38893.1 - 0.014 14.9 7.2 0.017 14.6 7.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PVD38893.1 - 0.039 14.0 7.6 0.04 14.0 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator IL11 PF07400.11 PVD38893.1 - 0.15 11.7 0.5 0.17 11.5 0.5 1.1 1 0 0 1 1 1 0 Interleukin 11 G-alpha PF00503.20 PVD38894.1 - 6.1e-15 55.2 0.0 7.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit MCM PF00493.23 PVD38894.1 - 0.00078 18.6 0.1 0.00098 18.3 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 PVD38894.1 - 0.00087 19.7 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 PVD38894.1 - 0.0017 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 PVD38894.1 - 0.0023 17.2 0.2 0.003 16.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 PVD38894.1 - 0.0028 17.4 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 PVD38894.1 - 0.0073 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 PVD38894.1 - 0.0078 15.5 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 PVD38894.1 - 0.0094 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PVD38894.1 - 0.01 16.4 0.1 0.013 16.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 PVD38894.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 PVD38894.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 PVD38894.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 PVD38894.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PVD38894.1 - 0.019 15.2 0.1 0.073 13.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PVD38894.1 - 0.02 14.9 0.2 0.031 14.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PVD38894.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 PVD38894.1 - 0.026 14.4 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain GTP_EFTU PF00009.27 PVD38894.1 - 0.029 13.9 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.21 PVD38894.1 - 0.03 13.8 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PVD38894.1 - 0.041 14.0 0.1 0.11 12.5 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 PVD38894.1 - 0.049 13.8 0.3 0.098 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD38894.1 - 0.052 13.5 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 PVD38894.1 - 0.059 13.8 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 PVD38894.1 - 0.068 12.3 0.1 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 PVD38894.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 PVD38894.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PVD38894.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 PVD38895.1 - 3.9e-31 108.5 0.2 5.2e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD38895.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Srg PF02118.21 PVD38895.1 - 0.12 12.1 0.4 0.15 11.7 0.4 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor SEFIR PF08357.11 PVD38896.1 - 6e-15 55.8 0.0 1.2e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 SEFIR domain CarboxypepD_reg PF13620.6 PVD38896.1 - 0.011 15.9 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 PVD38896.1 - 0.027 14.7 0.4 0.064 13.5 0.4 1.6 1 0 0 1 1 1 0 SdrD B-like domain zf_CCCH_4 PF18345.1 PVD38896.1 - 0.37 10.9 7.2 0.39 10.8 1.4 2.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 PVD38896.1 - 1.5 8.7 4.4 0.61 10.0 0.9 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger PCAF_N PF06466.11 PVD38897.1 - 1.8e-109 365.2 0.3 5.4e-109 363.6 0.3 1.8 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 PVD38897.1 - 9.3e-23 80.1 0.6 2.5e-22 78.8 0.6 1.8 1 0 0 1 1 1 1 Bromodomain SEFIR PF08357.11 PVD38897.1 - 7.9e-10 39.2 0.1 1.7e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 SEFIR domain Acetyltransf_1 PF00583.25 PVD38897.1 - 1.2e-09 38.4 0.0 3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PVD38897.1 - 5.2e-06 26.4 0.1 1.2e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PVD38897.1 - 5.1e-05 23.6 0.2 0.00012 22.4 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CAP-ZIP_m PF15255.6 PVD38897.1 - 0.075 13.3 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region PDZ PF00595.24 PVD38898.1 - 2.1e-14 53.6 0.0 3.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 PVD38898.1 - 2.3e-09 38.2 0.1 7.3e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 PVD38898.1 - 2.8e-07 30.3 0.1 5.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD38898.1 - 8.4e-05 22.8 0.0 0.00032 21.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain 7tm_1 PF00001.21 PVD38899.1 - 4e-53 180.4 22.7 4.8e-53 180.1 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38899.1 - 2.3e-12 46.8 20.3 3.4e-12 46.3 20.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD38899.1 - 1.5e-10 41.2 26.4 1.9e-10 40.9 24.5 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 PVD38899.1 - 8e-07 28.6 19.8 3.4e-05 23.3 19.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 PVD38899.1 - 5.3e-05 23.1 17.6 8.7e-05 22.4 17.6 1.3 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 PVD38900.1 - 1.8e-55 188.1 23.3 2.4e-55 187.7 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38900.1 - 2.5e-12 46.7 23.4 3.5e-12 46.2 23.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD38900.1 - 2e-10 40.7 27.8 3.5e-10 40.0 26.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD38900.1 - 2.7e-10 40.1 23.6 3.5e-10 39.7 23.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD38900.1 - 9e-08 31.8 24.8 1.1e-06 28.2 24.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 PVD38900.1 - 0.00012 21.9 21.8 0.00017 21.4 21.8 1.1 1 0 0 1 1 1 1 Olfactory receptor FA_desaturase PF00487.24 PVD38900.1 - 1.7 8.4 13.1 0.039 13.8 1.9 2.4 1 1 2 3 3 3 0 Fatty acid desaturase C1q PF00386.21 PVD38901.1 - 5.6e-18 65.4 0.0 9.6e-18 64.6 0.0 1.4 1 1 0 1 1 1 1 C1q domain FapA PF03961.13 PVD38901.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ependymin PF00811.18 PVD38902.1 - 5.5e-12 46.0 0.1 9.5e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Ependymin BRICHOS PF04089.14 PVD38902.1 - 0.024 14.9 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 BRICHOS domain Ependymin PF00811.18 PVD38903.1 - 7.6e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Ependymin K1 PF02960.14 PVD38904.1 - 0.069 13.3 0.8 0.17 12.0 0.8 1.7 1 0 0 1 1 1 0 K1 glycoprotein SLR1-BP PF07333.12 PVD38904.1 - 0.54 10.8 10.7 1.2 9.7 10.7 1.6 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Plasmod_Pvs28 PF06247.11 PVD38904.1 - 0.59 10.5 8.8 1.5 9.2 8.8 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain Urate_ox_N PF06181.11 PVD38905.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal 7tm_1 PF00001.21 PVD38908.1 - 6.2e-52 176.5 18.0 9.4e-52 175.9 18.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD38908.1 - 1.1e-11 45.0 12.7 8.2e-11 42.2 12.7 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD38908.1 - 1.3e-07 31.3 15.8 1.7e-07 30.9 15.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 PVD38909.1 - 8.9e-12 44.9 0.5 1.3e-11 44.4 0.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 PVD38909.1 - 2.7e-07 30.6 0.8 3.2e-07 30.4 0.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 PVD38909.1 - 0.0013 18.2 0.2 0.0016 17.9 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Wzy_C PF04932.15 PVD38909.1 - 0.12 12.0 0.3 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2298 PF10060.9 PVD38910.1 - 0.0047 15.7 1.5 0.0056 15.5 1.5 1.1 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) NAT PF04768.13 PVD38912.1 - 4.5e-41 140.3 1.2 1.3e-40 138.8 1.2 1.7 1 1 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 PVD38912.1 - 0.0074 15.9 0.0 0.13 11.9 0.0 2.3 1 1 0 1 1 1 1 Amino acid kinase family DUF3024 PF11225.8 PVD38912.1 - 1.7 9.0 4.2 1.9 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3024) DUF4381 PF14316.6 PVD38914.1 - 0.015 15.5 0.3 0.023 14.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MAP17 PF15807.5 PVD38914.1 - 0.058 13.6 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM151 PF14857.6 PVD38914.1 - 0.088 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM151 family DUF648 PF04890.13 PVD38914.1 - 0.19 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) SIT PF15330.6 PVD38914.1 - 0.2 12.1 0.0 0.38 11.2 0.0 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Annexin PF00191.20 PVD38915.1 - 2.1e-95 312.8 11.2 3.4e-26 91.1 0.2 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 PVD38915.1 - 0.004 17.0 2.4 1.9 8.4 0.0 3.4 4 0 0 4 4 4 2 Myb DNA-binding like Sigma70_ner PF04546.13 PVD38915.1 - 0.02 14.8 1.0 0.048 13.5 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2312 PF10073.9 PVD38915.1 - 0.092 12.4 3.6 3.9 7.2 0.4 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4562 PF15123.6 PVD38916.1 - 2e-17 63.2 0.0 4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) Dpy-30 PF05186.13 PVD38917.1 - 2.9e-12 46.0 0.0 5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Presenilin PF01080.17 PVD38917.1 - 1.8 7.2 6.5 2 7.1 6.5 1.1 1 0 0 1 1 1 0 Presenilin Pur_DNA_glyco PF02245.16 PVD38918.1 - 1.3e-56 190.8 0.0 1.8e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Pkinase PF00069.25 PVD38919.1 - 3.1e-64 216.9 0.0 5.6e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 PVD38919.1 - 5.5e-40 135.3 0.1 4.8e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 PVD38919.1 - 4e-32 111.5 0.0 8.5e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD38919.1 - 2e-05 24.1 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PVD38919.1 - 0.0012 18.8 0.0 0.093 12.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cupin_3 PF05899.12 PVD38919.1 - 0.055 13.2 1.1 9 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Seadorna_VP7 PF07387.11 PVD38919.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Med4 PF10018.9 PVD38920.1 - 0.0033 17.1 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.12 PVD38920.1 - 0.0064 16.9 0.1 0.0089 16.5 0.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein PV-1 PF06637.11 PVD38920.1 - 0.0082 15.0 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) PKcGMP_CC PF16808.5 PVD38920.1 - 0.015 15.1 9.1 0.015 15.1 9.1 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V-SNARE PF05008.15 PVD38920.1 - 0.021 15.2 1.3 0.029 14.7 1.3 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Tsc35 PF15079.6 PVD38920.1 - 0.028 14.0 0.3 0.039 13.5 0.3 1.1 1 0 0 1 1 1 0 Testis-specific protein 35 PhoU PF01895.19 PVD38920.1 - 0.035 14.6 0.8 0.047 14.1 0.8 1.2 1 0 0 1 1 1 0 PhoU domain FlgN PF05130.12 PVD38920.1 - 0.036 14.6 0.9 0.039 14.4 0.9 1.1 1 0 0 1 1 1 0 FlgN protein Spc42p PF11544.8 PVD38920.1 - 0.05 13.6 0.8 0.077 13.0 0.8 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF4200 PF13863.6 PVD38920.1 - 0.087 13.2 4.2 0.12 12.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4763 PF15960.5 PVD38920.1 - 0.15 11.3 2.1 0.21 10.9 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF641 PF04859.12 PVD38920.1 - 0.2 12.0 2.0 0.27 11.6 2.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Tox-REase-2 PF15646.6 PVD38920.1 - 0.22 11.7 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 Syntaphilin PF15290.6 PVD38920.1 - 1.1 8.9 3.2 1.3 8.6 3.2 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp PKcGMP_CC PF16808.5 PVD38922.1 - 1.4e-12 47.3 9.5 1.8e-12 46.8 9.5 1.2 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase P4Ha_N PF08336.11 PVD38922.1 - 0.00014 21.8 1.6 0.00018 21.6 1.6 1.1 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc29 PF17082.5 PVD38922.1 - 0.00022 21.2 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 CCDC106 PF15794.5 PVD38922.1 - 0.00095 18.9 0.1 0.00095 18.9 0.1 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 HAUS5 PF14817.6 PVD38922.1 - 0.0032 16.3 0.8 0.0038 16.1 0.8 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Med4 PF10018.9 PVD38922.1 - 0.0037 16.9 0.5 0.0043 16.7 0.5 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 XLF PF09302.11 PVD38922.1 - 0.0059 16.8 1.2 0.0076 16.4 1.2 1.1 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Viral_env_E26 PF11050.8 PVD38922.1 - 0.013 14.9 0.4 0.017 14.5 0.4 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 FlgN PF05130.12 PVD38922.1 - 0.019 15.5 0.5 0.021 15.4 0.5 1.1 1 0 0 1 1 1 0 FlgN protein Bacillus_HBL PF05791.11 PVD38922.1 - 0.019 14.8 0.5 0.023 14.5 0.5 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4763 PF15960.5 PVD38922.1 - 0.023 14.0 1.0 0.036 13.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TMF_DNA_bd PF12329.8 PVD38922.1 - 0.036 14.1 7.6 0.29 11.2 0.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 PVD38922.1 - 0.037 14.2 1.4 0.15 12.2 1.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_N PF02465.18 PVD38922.1 - 0.043 14.5 0.0 0.049 14.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Syntaxin_2 PF14523.6 PVD38922.1 - 0.052 13.9 1.5 0.25 11.7 0.1 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF16 PF01519.16 PVD38922.1 - 0.087 13.3 1.5 0.12 12.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 UDPGT PF00201.18 PVD38923.1 - 7.1e-35 120.7 0.0 1.3e-34 119.9 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase KbaA PF14089.6 PVD38923.1 - 0.038 13.8 1.2 0.068 13.0 1.2 1.3 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation UDPGT PF00201.18 PVD38924.1 - 4.6e-61 207.1 0.0 6.8e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD38924.1 - 0.0067 16.4 0.0 0.062 13.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain CAP PF00188.26 PVD38925.1 - 2.4e-17 63.9 0.0 3.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 PVD38926.1 - 2.1e-18 67.4 0.1 2.8e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 PVD38927.1 - 2.6e-10 41.2 0.0 3.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BRCT_3 PF18428.1 PVD38927.1 - 0.054 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 PVD38929.1 - 8.8e-154 500.3 57.1 2.7e-14 53.3 0.3 14.0 13 0 0 13 13 13 13 Fibronectin type III domain Ig_3 PF13927.6 PVD38929.1 - 1.5e-60 201.7 15.9 6.7e-13 49.0 0.3 8.1 8 0 0 8 8 7 5 Immunoglobulin domain I-set PF07679.16 PVD38929.1 - 5.1e-60 199.6 0.2 6.2e-13 48.6 0.0 7.6 7 0 0 7 7 7 6 Immunoglobulin I-set domain ig PF00047.25 PVD38929.1 - 4.7e-37 126.1 0.6 9.5e-09 35.3 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 PVD38929.1 - 1.1e-29 102.5 7.3 3.7e-06 27.2 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 PVD38929.1 - 2.1e-15 56.9 7.6 0.16 12.1 0.0 9.6 8 3 0 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 PVD38929.1 - 4.3e-11 43.2 40.0 0.21 12.2 0.6 13.1 14 0 0 14 14 13 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 PVD38929.1 - 1.8e-07 31.4 2.1 0.66 10.3 0.1 7.1 8 0 0 8 8 7 2 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 PVD38929.1 - 3.4e-06 27.0 0.0 0.44 10.6 0.0 5.6 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 PVD38929.1 - 0.00012 22.1 1.8 6.3 7.0 0.0 4.7 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 PVD38929.1 - 0.00021 21.7 0.0 1.5 9.2 0.0 4.9 5 0 0 5 5 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 PVD38929.1 - 0.00047 19.7 0.1 22 4.7 0.0 4.9 5 0 0 5 5 5 0 Immunoglobulin domain Ig_4 PF16680.5 PVD38929.1 - 0.0049 17.1 0.3 11 6.3 0.0 4.1 4 0 0 4 4 3 0 T-cell surface glycoprotein CD3 delta chain Herpes_gE PF02480.16 PVD38929.1 - 0.0078 15.0 0.9 1.5 7.4 0.0 3.0 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 PVD38929.1 - 0.017 15.3 0.5 11 6.3 0.0 5.1 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 EphA2_TM PF14575.6 PVD38929.1 - 0.02 15.8 0.0 0.044 14.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain C2-set PF05790.15 PVD38929.1 - 0.041 14.1 0.0 1.7 8.9 0.0 3.5 4 0 0 4 4 4 0 Immunoglobulin C2-set domain 7tm_1 PF00001.21 PVD38930.1 - 7.6e-13 48.4 1.0 7.6e-13 48.4 1.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38930.1 - 0.00057 19.3 1.5 0.0007 19.1 1.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 PVD38930.1 - 0.1 12.3 4.4 0.035 13.8 2.3 1.3 1 1 0 1 1 1 0 Olfactory receptor GPR_Gpa2_C PF11970.8 PVD38930.1 - 0.18 11.9 2.1 0.28 11.3 2.1 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 PVD38931.1 - 3.3e-12 46.3 3.0 3.5e-11 42.9 3.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD38931.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Pur_DNA_glyco PF02245.16 PVD38932.1 - 5.7e-24 84.5 0.5 2.3e-14 53.2 0.0 2.3 1 1 1 2 2 2 2 Methylpurine-DNA glycosylase (MPG) Linker_histone PF00538.19 PVD38932.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family IRF PF00605.17 PVD38933.1 - 4.6e-30 104.0 1.7 9.2e-30 103.0 1.7 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Ank PF00023.30 PVD38934.1 - 2.3e-12 46.8 0.2 0.0004 20.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 PVD38934.1 - 3.5e-12 46.7 0.0 5.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD38934.1 - 2.2e-08 33.7 0.1 6.8e-05 23.0 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PVD38934.1 - 2.7e-07 31.0 0.1 6.4e-05 23.4 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD38934.1 - 3.4e-07 30.4 0.3 3e-05 24.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GATase_7 PF13537.6 PVD38934.1 - 0.077 12.9 0.0 1.6 8.7 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase domain PEGA PF08308.11 PVD38934.1 - 0.14 12.1 0.0 5.7 6.9 0.0 2.2 2 0 0 2 2 2 0 PEGA domain Ank PF00023.30 PVD38935.1 - 1.3e-11 44.4 1.8 1.4e-06 28.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PVD38935.1 - 2.5e-09 36.6 0.2 2.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PVD38935.1 - 1.9e-08 34.8 0.0 8e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD38935.1 - 2.4e-06 27.7 0.2 8e-05 22.9 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD38935.1 - 8e-06 26.3 0.1 0.00057 20.4 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) ARA70 PF12489.8 PVD38937.1 - 9.8e-12 45.2 0.8 9.8e-12 45.2 0.8 4.7 4 2 0 4 4 4 1 Nuclear coactivator SMBP PF16785.5 PVD38937.1 - 0.011 15.9 2.6 0.022 14.9 2.6 1.5 1 0 0 1 1 1 0 Small metal-binding protein DUF222 PF02720.17 PVD38937.1 - 0.02 14.3 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF222) Tn7_Tnp_TnsA_C PF08721.11 PVD38937.1 - 0.095 13.3 1.1 0.54 10.9 0.0 2.8 3 0 0 3 3 3 0 TnsA endonuclease C terminal Spore_III_AB PF09548.10 PVD38937.1 - 1.5 8.9 4.8 6.6 6.8 4.8 2.2 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SlyX PF04102.12 PVD38937.1 - 1.8 9.2 5.2 1.3 9.7 0.2 2.8 2 1 0 2 2 2 0 SlyX CLZ PF16526.5 PVD38937.1 - 2.5 8.5 5.6 3.1 8.2 1.3 2.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Death PF00531.22 PVD38938.1 - 3.4e-15 56.0 0.2 6.6e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Death domain Zip PF02535.22 PVD38939.1 - 0.45 9.7 11.5 0.44 9.7 11.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 PVD38939.1 - 1.2 8.5 3.9 1.2 8.5 3.9 1.1 1 0 0 1 1 1 0 FAM76 protein AIM3 PF17096.5 PVD38939.1 - 5.2 8.1 8.9 10 7.2 8.9 1.6 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Ank_2 PF12796.7 PVD38940.1 - 2.9e-144 470.0 39.8 7.4e-18 64.9 0.5 12.0 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 PVD38940.1 - 1.6e-130 420.4 57.8 9.9e-08 32.1 0.1 22.2 21 1 1 22 22 22 20 Ankyrin repeat Ank_4 PF13637.6 PVD38940.1 - 1.2e-121 395.6 53.9 2.2e-12 47.2 0.2 15.7 5 2 13 19 19 19 18 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD38940.1 - 2.4e-119 387.8 38.5 2.5e-12 46.8 0.0 15.7 5 3 14 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD38940.1 - 6.5e-111 348.7 31.9 1.5e-05 25.0 0.0 22.5 23 0 0 23 23 23 19 Ankyrin repeat UPA_2 PF17809.1 PVD38940.1 - 5.2e-51 171.9 0.1 1.4e-50 170.5 0.1 1.8 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 PVD38940.1 - 2e-35 121.0 1.7 2.3e-27 95.2 0.0 3.0 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 PVD38940.1 - 2.7e-17 62.7 0.6 6.4e-17 61.5 0.6 1.7 1 0 0 1 1 1 1 Death domain Peptidase_M16 PF00675.20 PVD38941.1 - 1.6e-27 96.3 0.3 3.5e-25 88.7 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PVD38941.1 - 4.4e-24 85.5 0.3 1e-22 81.0 0.2 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain MT-A70 PF05063.14 PVD38942.1 - 9.8e-60 201.4 0.1 1.3e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 MT-A70 AIM3 PF17096.5 PVD38942.1 - 0.18 12.7 3.3 0.39 11.7 3.3 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 CHCH PF06747.13 PVD38943.1 - 4.4e-06 26.7 5.9 7.2e-06 26.0 5.9 1.3 1 0 0 1 1 1 1 CHCH domain CoA_trans PF01144.23 PVD38943.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Coenzyme A transferase CX9C PF16860.5 PVD38943.1 - 0.0076 16.2 0.6 0.0076 16.2 0.6 2.0 1 1 1 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 PVD38943.1 - 0.018 15.2 2.3 0.027 14.7 2.3 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Colipase-like PF15083.6 PVD38943.1 - 0.05 13.7 1.6 0.074 13.2 1.6 1.3 1 0 0 1 1 1 0 Colipase-like Toxin_3 PF00537.18 PVD38943.1 - 0.14 12.3 0.8 0.22 11.7 0.8 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain PIN_5 PF08745.11 PVD38943.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 PINc domain ribonuclease wnt PF00110.19 PVD38944.1 - 8e-12 45.4 0.7 9.1e-12 45.2 0.7 1.1 1 0 0 1 1 1 1 wnt family Anp1 PF03452.14 PVD38944.1 - 0.022 14.2 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Anp1 DUF4808 PF16066.5 PVD38944.1 - 0.061 13.9 0.3 0.093 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) PKD PF00801.20 PVD38947.1 - 2.2e-21 75.5 30.3 1.6e-12 47.0 5.3 6.4 5 2 0 5 5 5 5 PKD domain REJ PF02010.15 PVD38947.1 - 4.3e-12 45.6 2.2 8e-12 44.7 0.1 2.2 2 0 0 2 2 2 1 REJ domain WSC PF01822.19 PVD38947.1 - 0.0039 17.3 1.0 0.011 15.9 1.0 1.8 1 0 0 1 1 1 1 WSC domain PLAT PF01477.23 PVD38948.1 - 7.3e-12 45.9 0.1 7.9e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 PLAT/LH2 domain GPS PF01825.21 PVD38948.1 - 2.6e-08 34.3 8.7 7.5e-08 32.8 8.7 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Sigma_reg_N PF13800.6 PVD38948.1 - 0.32 11.3 5.3 57 4.1 0.1 3.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal BPD_transp_1 PF00528.22 PVD38948.1 - 1.4 8.6 6.5 6.1 6.5 0.1 3.3 4 0 0 4 4 4 0 Binding-protein-dependent transport system inner membrane component PKD_channel PF08016.12 PVD38949.1 - 8e-90 301.5 15.4 8.9e-90 301.4 15.4 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PVD38949.1 - 5.7e-10 38.8 27.4 8.7e-10 38.2 27.4 1.3 1 0 0 1 1 1 1 Ion transport protein HORMA PF02301.18 PVD38950.1 - 2.5e-23 82.8 0.3 3.8e-23 82.2 0.3 1.3 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 PVD38950.1 - 0.00017 21.6 1.0 0.002 18.1 1.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 TFIIE_alpha PF02002.17 PVD38950.1 - 0.019 14.8 5.4 0.032 14.1 5.4 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit YojJ PF10372.9 PVD38950.1 - 0.63 10.2 2.4 23 5.2 0.3 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF4342 PF14242.6 PVD38950.1 - 1.5 8.9 5.7 1.9 8.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Ocnus PF05005.15 PVD38951.1 - 3e-37 127.0 0.0 3.4e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Linker_histone PF00538.19 PVD38952.1 - 0.074 13.4 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family Ephrin_rec_like PF07699.13 PVD38954.1 - 3e-05 23.7 49.7 8.5e-05 22.2 2.6 125.6 90 33 25 123 123 123 69 Putative ephrin-receptor like DUF4863 PF16155.5 PVD38954.1 - 1.9 8.4 4.0 9.5 6.1 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4863) T5orf172 PF10544.9 PVD38956.1 - 0.095 13.2 0.5 0.18 12.4 0.1 1.7 1 1 1 2 2 2 0 T5orf172 domain Ion_trans PF00520.31 PVD38958.1 - 3e-31 108.5 13.7 4.1e-31 108.1 13.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 PVD38958.1 - 1.1e-12 47.8 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PVD38958.1 - 1.6e-10 40.8 0.3 1.6e-10 40.8 0.3 2.4 3 0 0 3 3 3 1 Ion channel Sipho_Gp157 PF05565.11 PVD38958.1 - 0.041 13.9 0.1 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF948 PF06103.11 PVD38958.1 - 0.053 13.8 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) wnt PF00110.19 PVD38960.1 - 3.8e-119 397.9 25.3 4.9e-119 397.5 25.3 1.1 1 0 0 1 1 1 1 wnt family CABIT PF12736.7 PVD38960.1 - 6.3e-05 22.4 0.3 0.00011 21.6 0.3 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, Fructosamin_kin PF03881.14 PVD38960.1 - 0.037 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase wnt PF00110.19 PVD38961.1 - 4.3e-51 174.3 4.9 5.4e-51 174.0 4.9 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 PVD38962.1 - 1.2e-15 57.9 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 wnt family Pro_isomerase PF00160.21 PVD38962.1 - 0.14 12.4 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD wnt PF00110.19 PVD38964.1 - 6.3e-28 98.3 2.1 6.8e-28 98.2 2.1 1.2 1 0 0 1 1 1 1 wnt family AAA PF00004.29 PVD38965.1 - 2.3e-54 183.4 0.0 1.9e-39 135.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PVD38965.1 - 5.2e-11 42.2 0.1 1.3e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PVD38965.1 - 8.9e-08 32.5 0.2 0.0046 17.2 0.1 4.4 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 PVD38965.1 - 2.3e-07 31.1 0.1 2.3e-05 24.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 PVD38965.1 - 2.4e-07 30.8 0.0 2.9e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 PVD38965.1 - 4.5e-07 30.4 0.1 0.06 13.7 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 PVD38965.1 - 5.7e-07 29.1 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 PVD38965.1 - 1.3e-06 29.0 0.0 0.025 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PVD38965.1 - 1.7e-06 28.1 0.5 0.0014 18.7 0.2 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PVD38965.1 - 4.3e-06 26.6 0.1 0.025 14.3 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PVD38965.1 - 6.3e-06 25.7 0.5 0.0081 15.6 0.2 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PVD38965.1 - 3.9e-05 23.8 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PVD38965.1 - 6.1e-05 23.1 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PVD38965.1 - 0.00036 20.9 0.0 0.1 13.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 PVD38965.1 - 0.00051 19.8 0.0 0.22 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PVD38965.1 - 0.001 19.0 0.3 4.2 7.2 0.0 3.6 4 0 0 4 4 4 1 NACHT domain TsaE PF02367.17 PVD38965.1 - 0.0011 18.9 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_2 PF02933.17 PVD38965.1 - 0.0021 17.8 1.0 0.038 13.8 0.0 3.1 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 PVD38965.1 - 0.0024 17.2 1.2 0.009 15.4 0.1 2.4 3 0 0 3 3 2 1 KaiC AAA_7 PF12775.7 PVD38965.1 - 0.0025 17.4 0.0 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region KTI12 PF08433.10 PVD38965.1 - 0.0062 16.0 0.1 1.8 7.9 0.0 2.6 3 0 0 3 3 2 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 PVD38965.1 - 0.0062 16.3 0.3 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_3 PF07726.11 PVD38965.1 - 0.0085 15.9 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PVD38965.1 - 0.0096 16.4 0.1 0.089 13.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 PVD38965.1 - 0.017 14.9 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 PVD38965.1 - 0.017 15.5 1.0 1.3 9.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 PVD38965.1 - 0.018 14.7 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PVD38965.1 - 0.02 14.4 1.1 2.3 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 PVD38965.1 - 0.024 14.4 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PVD38965.1 - 0.04 13.1 0.0 6.4 5.9 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 PVD38965.1 - 0.044 14.2 0.0 9.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PVD38965.1 - 0.045 13.7 0.8 44 3.9 0.0 3.9 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea CPT PF07931.12 PVD38965.1 - 0.052 13.4 0.0 0.77 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 PVD38965.1 - 0.066 12.3 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 PVD38965.1 - 0.087 13.1 0.0 5 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PVD38965.1 - 0.11 11.7 0.3 4.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Gly_transf_sug PF04488.15 PVD38966.1 - 5.1e-08 33.4 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PVD38966.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain SNF PF00209.18 PVD38967.1 - 6.2e-127 424.4 11.9 7.2e-127 424.2 11.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2220 PF09983.9 PVD38967.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) 7tm_3 PF00003.22 PVD38969.1 - 4e-36 124.9 17.1 1.3e-35 123.2 17.1 1.7 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EIIC-GAT PF03611.14 PVD38969.1 - 1.3e-05 24.5 4.1 2.1e-05 23.8 4.1 1.3 1 0 0 1 1 1 1 PTS system sugar-specific permease component SelP_N PF04592.14 PVD38969.1 - 5.2 6.4 12.9 4 6.8 11.1 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Herpes_US9 PF06072.11 PVD38971.1 - 0.0083 16.0 2.4 0.012 15.4 2.4 1.2 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 Anoctamin PF04547.12 PVD38971.1 - 0.024 13.5 0.0 0.029 13.2 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF5542 PF17696.1 PVD38971.1 - 5.9 7.1 6.4 11 6.2 6.4 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5542) 7tm_1 PF00001.21 PVD38972.1 - 7.6e-31 107.4 10.5 1.2e-30 106.7 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD38972.1 - 2.4e-09 37.2 4.6 4e-09 36.5 4.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PrmA PF06325.13 PVD38972.1 - 1.9e-08 34.0 0.2 3.1e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PVD38972.1 - 4.1e-08 33.8 0.1 3.7e-07 30.8 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 PVD38972.1 - 7.4e-08 32.1 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain 7TM_GPCR_Srsx PF10320.9 PVD38972.1 - 1.3e-06 28.0 6.4 2.5e-05 23.8 3.9 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx SH3_2 PF07653.17 PVD38972.1 - 2.1e-06 27.3 0.0 4.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_18 PF12847.7 PVD38972.1 - 7.3e-06 26.0 0.2 1.4e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain SH3_1 PF00018.28 PVD38972.1 - 8.4e-06 25.3 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PRMT5 PF05185.16 PVD38972.1 - 3.7e-05 23.6 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 PVD38972.1 - 3.9e-05 23.5 0.1 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PVD38972.1 - 8e-05 23.2 0.0 0.00024 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PVD38972.1 - 0.00013 21.9 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PVD38972.1 - 0.00023 20.6 0.1 0.00049 19.6 0.1 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.16 PVD38972.1 - 0.00027 20.7 0.1 0.0005 19.9 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein SH3_9 PF14604.6 PVD38972.1 - 0.00061 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_16 PF10294.9 PVD38972.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 PVD38972.1 - 0.0024 18.6 0.0 0.0069 17.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PVD38972.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) 7tm_4 PF13853.6 PVD38972.1 - 0.013 15.3 10.5 0.01 15.6 6.5 2.5 2 1 0 2 2 2 0 Olfactory receptor CMAS PF02353.20 PVD38972.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 PVD38972.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 PVD38972.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7TM_GPCR_Srw PF10324.9 PVD38972.1 - 2.4 7.4 6.8 4.4 6.5 6.8 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 PVD38972.1 - 2.6 7.3 12.5 0.48 9.7 5.9 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Thioredoxin_6 PF13848.6 PVD38973.1 - 2.5e-44 151.4 0.7 5.2e-39 134.1 0.2 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 PVD38973.1 - 3.3e-22 78.4 0.0 7.5e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 PVD38973.1 - 2e-11 43.5 0.0 3.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 PVD38973.1 - 0.00042 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PVD38973.1 - 0.024 15.0 0.0 0.83 10.0 0.0 2.7 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 PVD38973.1 - 0.054 13.5 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE PHTB1_N PF14727.6 PVD38974.1 - 2.7e-154 514.5 0.0 3.4e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 PVD38974.1 - 2.2e-138 461.5 0.0 2.8e-138 461.1 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Sec23_BS PF08033.12 PVD38974.1 - 0.066 14.0 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain DNA_primase_lrg PF04104.14 PVD38975.1 - 1.7e-29 103.0 0.3 3.1e-29 102.2 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SRI PF08236.11 PVD38976.1 - 1.6e-23 82.7 6.7 9e-23 80.3 6.7 2.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 PVD38976.1 - 1.4e-10 41.1 3.3 3.2e-10 39.9 3.3 1.7 1 0 0 1 1 1 1 WW domain AWS PF17907.1 PVD38976.1 - 2.4e-10 40.2 6.7 2.4e-10 40.2 6.7 2.0 2 0 0 2 2 2 1 AWS domain SET PF00856.28 PVD38976.1 - 8.8e-07 29.5 0.0 8.8e-07 29.5 0.0 7.2 7 2 0 7 7 7 1 SET domain SUI1 PF01253.22 PVD38977.1 - 1.2e-25 89.8 1.1 1.5e-25 89.5 1.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_L31 PF01197.18 PVD38977.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L31 DUF2575 PF10837.8 PVD38977.1 - 0.054 13.8 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) TLP-20 PF06088.11 PVD38978.1 - 0.044 13.7 0.1 0.056 13.3 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) La PF05383.17 PVD38980.1 - 2.8e-20 72.1 0.7 5.7e-20 71.1 0.7 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 PVD38980.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RFamide_26RFa PF11109.8 PVD38980.1 - 0.061 13.8 0.5 0.061 13.8 0.5 2.5 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 Exo_endo_phos_2 PF14529.6 PVD38981.1 - 2.6e-17 62.8 6.3 8.6e-17 61.1 0.7 3.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PVD38981.1 - 8.6e-12 45.1 0.1 3.4e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1978 PF09321.10 PVD38981.1 - 0.00058 19.3 0.7 0.00058 19.3 0.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1978) DUF1387 PF07139.11 PVD38982.1 - 4e-54 184.5 7.4 4e-54 184.5 7.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) CUE PF02845.16 PVD38982.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 PVD38982.1 - 0.0031 17.6 0.1 0.0031 17.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) HBS1_N PF08938.10 PVD38982.1 - 0.016 15.5 2.0 0.045 14.0 0.3 2.7 2 0 0 2 2 2 0 HBS1 N-terminus UBA_4 PF14555.6 PVD38982.1 - 0.018 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Flagellin_C PF00700.21 PVD38983.1 - 0.009 16.3 0.5 0.009 16.3 0.5 2.7 2 0 0 2 2 2 1 Bacterial flagellin C-terminal helical region F420H2_quin_red PF04075.14 PVD38983.1 - 0.072 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase Peptidase_S64 PF08192.11 PVD38983.1 - 0.11 11.0 27.0 0.14 10.6 27.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Frizzled PF01534.17 PVD38985.1 - 1.6e-141 471.1 17.6 2.2e-141 470.6 17.6 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 PVD38985.1 - 5.9e-35 120.3 4.1 1.5e-34 118.9 4.1 1.7 1 0 0 1 1 1 1 Fz domain DUF3493 PF11998.8 PVD38985.1 - 0.25 11.5 0.8 0.55 10.4 0.2 1.8 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Transmemb_17 PF09799.9 PVD38985.1 - 2.7 8.6 11.6 5.2 7.7 6.7 3.2 2 1 1 3 3 3 0 Predicted membrane protein DUF5428 PF17493.2 PVD38986.1 - 1.4 9.4 3.3 0.92 10.0 0.6 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5428) zf-C3HC4_3 PF13920.6 PVD38988.1 - 8.1e-10 38.4 8.5 1.6e-09 37.5 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD38988.1 - 0.00031 20.5 7.8 0.00062 19.6 7.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 PVD38988.1 - 0.069 13.5 6.6 0.14 12.5 6.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 PVD38988.1 - 0.14 12.2 10.0 0.32 11.0 10.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain SDA1 PF05285.12 PVD38989.1 - 0.00034 20.2 1.4 0.00034 20.2 1.4 1.2 1 0 0 1 1 1 1 SDA1 TRAP_alpha PF03896.16 PVD38989.1 - 0.019 14.2 3.3 0.024 13.9 3.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 PVD38989.1 - 0.065 11.5 4.1 0.068 11.5 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 PVD38989.1 - 0.11 10.3 2.6 0.14 9.9 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RecT PF03837.14 PVD38989.1 - 0.11 11.9 1.2 0.16 11.5 1.2 1.2 1 0 0 1 1 1 0 RecT family RPA43_OB PF17875.1 PVD38989.1 - 0.16 12.6 2.4 0.29 11.8 2.4 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RRN3 PF05327.11 PVD38989.1 - 0.21 10.1 2.7 0.24 9.9 2.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 PVD38989.1 - 0.33 9.9 11.3 0.41 9.5 11.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein HSP90 PF00183.18 PVD38989.1 - 0.74 8.6 9.3 0.95 8.3 9.3 1.1 1 0 0 1 1 1 0 Hsp90 protein Nop14 PF04147.12 PVD38989.1 - 1.6 6.9 12.4 2 6.5 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PVD38989.1 - 3.8 5.5 15.5 4.8 5.2 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Adeno_terminal PF02459.15 PVD38989.1 - 5.3 5.3 8.3 6.7 5.0 8.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein NOA36 PF06524.12 PVD38989.1 - 6.2 6.0 15.0 9.7 5.4 15.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 PVD38989.1 - 8.3 6.9 14.4 16 6.0 14.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ERAP1_C PF11838.8 PVD38990.1 - 3.5e-94 315.9 0.2 2.3e-93 313.2 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD38990.1 - 3.3e-91 304.7 0.3 5.4e-91 304.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD38990.1 - 3.4e-54 183.9 0.1 6.1e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF5011 PF16403.5 PVD38990.1 - 0.17 12.1 0.4 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) ERAP1_C PF11838.8 PVD38993.1 - 9.3e-85 284.9 1.0 1.5e-84 284.2 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PVD38993.1 - 8.4e-80 267.4 0.1 1.5e-79 266.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PVD38993.1 - 4e-37 128.2 0.0 6.9e-36 124.2 0.0 2.2 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain Herpes_UL37_1 PF03970.13 PVD38993.1 - 0.11 11.7 1.7 2.5 7.2 0.0 2.9 2 1 1 3 3 3 0 Herpesvirus UL37 tegument protein PLAC8 PF04749.17 PVD38996.1 - 2.2e-21 76.7 2.3 2.5e-21 76.5 2.3 1.0 1 0 0 1 1 1 1 PLAC8 family Fer4_21 PF14697.6 PVD38996.1 - 1.4 9.1 6.6 0.092 12.9 1.0 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Neur_chan_LBD PF02931.23 PVD38998.1 - 6.6e-08 32.3 1.2 9.6e-08 31.7 0.3 1.6 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PVD38998.1 - 0.00043 20.4 5.3 0.00043 20.4 5.3 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Clc-like PF07062.12 PVD38998.1 - 0.0087 15.6 0.6 0.0087 15.6 0.6 1.8 1 1 0 1 1 1 1 Clc-like DUF5367 PF17329.2 PVD38998.1 - 4 7.6 8.8 0.19 11.9 2.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF2070 PF09843.9 PVD38998.1 - 5.2 5.2 11.0 7.8 4.6 11.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5368 PF17336.2 PVD38998.1 - 6.1 7.1 9.0 12 6.1 6.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5368) TPR_2 PF07719.17 PVD38999.1 - 2.1e-07 30.5 3.5 0.28 11.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PVD38999.1 - 2.4e-06 27.1 1.0 1.1 9.2 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat SET PF00856.28 PVD38999.1 - 1.6e-05 25.3 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.6 PVD38999.1 - 0.00016 21.9 6.0 0.00087 19.5 3.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PVD38999.1 - 0.00059 20.4 12.9 0.22 12.4 0.0 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat zf-MYND PF01753.18 PVD38999.1 - 0.0011 19.0 8.0 0.0011 19.0 8.0 2.4 2 1 0 2 2 1 1 MYND finger TPR_19 PF14559.6 PVD38999.1 - 0.0024 18.4 3.4 0.46 11.0 0.6 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD38999.1 - 0.0025 18.0 1.9 0.009 16.2 2.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PVD38999.1 - 0.0046 16.9 0.4 1.3 9.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PVD38999.1 - 0.02 15.5 2.2 0.02 15.5 2.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 PVD38999.1 - 0.082 13.3 0.4 0.57 10.6 0.3 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain zf-C3HC4_3 PF13920.6 PVD39000.1 - 1.2e-10 41.0 8.1 2.3e-10 40.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD39000.1 - 4.1e-06 26.5 7.0 8.2e-06 25.6 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD39000.1 - 0.0076 16.2 11.8 0.027 14.4 11.8 2.0 1 1 0 1 1 1 1 zinc-RING finger domain DUF2039 PF10217.9 PVD39000.1 - 0.36 11.2 7.9 0.75 10.2 7.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) AATF-Che1 PF13339.6 PVD39000.1 - 4.3 8.0 8.7 22 5.7 8.5 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor zf-C3HC4_3 PF13920.6 PVD39001.1 - 1.1e-09 38.0 8.4 1.6e-09 37.5 8.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD39001.1 - 0.00057 19.7 7.7 0.00098 18.9 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 PVD39001.1 - 0.033 14.5 6.4 0.06 13.7 6.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 PVD39001.1 - 0.45 10.5 11.2 0.87 9.6 11.2 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 PVD39001.1 - 3.8 7.9 11.7 12 6.4 11.9 1.7 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 PVD39002.1 - 2.2e-10 40.2 6.5 2.2e-10 40.2 6.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PVD39002.1 - 1e-05 25.3 6.9 2e-05 24.4 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PVD39002.1 - 0.00065 19.6 6.7 0.0014 18.6 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PVD39002.1 - 0.011 15.5 7.7 0.024 14.5 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TAL_effector PF03377.13 PVD39002.1 - 0.17 12.3 0.7 0.41 11.0 0.2 2.0 2 0 0 2 2 2 0 TAL effector repeat zf-RING_2 PF13639.6 PVD39002.1 - 0.2 12.0 10.6 0.16 12.3 8.5 1.9 2 0 0 2 2 2 0 Ring finger domain DUF2039 PF10217.9 PVD39002.1 - 0.25 11.7 3.3 0.62 10.4 3.3 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Frizzled PF01534.17 PVD39003.1 - 1.4e-141 471.3 18.5 1.8e-141 470.9 18.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 PVD39003.1 - 2.5e-33 115.0 4.6 2.5e-33 115.0 4.6 1.7 2 0 0 2 2 2 1 Fz domain PDZ_5 PF17817.1 PVD39008.1 - 2.1e-27 95.2 2.8 1.4e-26 92.5 2.8 2.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PVD39008.1 - 6e-12 45.7 1.5 6e-12 45.7 1.5 2.4 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 PVD39008.1 - 7e-12 45.3 0.0 1.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PVD39008.1 - 5.9e-08 33.0 0.1 1.2e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 PVD39008.1 - 0.00073 19.3 0.1 0.0028 17.5 0.1 2.1 1 0 0 1 1 1 1 PDZ domain UQ_con PF00179.26 PVD39009.1 - 1.1e-50 170.9 0.0 2.3e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNF2_N PF00176.23 PVD39009.1 - 1.1e-34 119.8 0.0 1.7e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PVD39009.1 - 1.6e-16 60.6 0.0 3.1e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PVD39009.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-E2_B PF14461.6 PVD39009.1 - 0.03 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B ResIII PF04851.15 PVD39009.1 - 0.031 14.3 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RWD PF05773.22 PVD39009.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 RWD domain HasA PF06438.12 PVD39009.1 - 0.053 13.2 0.1 0.091 12.4 0.1 1.3 1 0 0 1 1 1 0 Heme-binding protein A (HasA) UEV PF05743.13 PVD39009.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain TRP_2 PF08344.11 PVD39010.1 - 1.7e-27 95.4 1.5 3.2e-27 94.5 1.5 1.5 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 PVD39010.1 - 2.9e-18 66.0 13.1 2.9e-18 66.0 13.1 2.0 2 1 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 PVD39010.1 - 8.8e-11 42.2 4.9 5.1e-06 27.0 0.2 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD39010.1 - 5.9e-08 32.4 2.5 0.21 12.3 0.1 4.1 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.30 PVD39010.1 - 2.2e-05 24.7 2.6 0.11 13.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PVD39010.1 - 9.8e-05 22.6 0.8 2.4 8.6 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PVD39010.1 - 0.00039 20.9 1.2 0.23 12.1 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PKD_channel PF08016.12 PVD39010.1 - 0.12 11.0 13.0 0.33 9.6 0.8 2.8 3 0 0 3 3 3 0 Polycystin cation channel PID PF00640.23 PVD39013.1 - 3.4e-11 43.3 0.4 6.5e-11 42.4 0.4 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) RUN PF02759.19 PVD39013.1 - 2.7e-08 33.9 0.1 5.6e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 RUN domain Tet_JBP PF12851.7 PVD39013.1 - 0.003 16.9 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily PDZ PF00595.24 PVD39013.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 PVD39013.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Alpha_L_fucos PF01120.17 PVD39014.1 - 5.4e-119 397.7 12.8 7.3e-119 397.3 12.8 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PVD39014.1 - 7e-25 87.4 0.0 1.5e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 PVD39014.1 - 0.061 13.4 0.1 0.3 11.2 0.1 2.2 1 1 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator SecIII_SopE_N PF05364.14 PVD39015.1 - 0.028 14.5 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus DUF2282 PF10048.9 PVD39016.1 - 0.81 9.7 3.1 3.7 7.6 0.2 3.1 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2282) Alpha_L_fucos PF01120.17 PVD39017.1 - 4.4e-90 302.6 1.7 6.1e-90 302.2 1.7 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PVD39017.1 - 1.1e-25 89.9 0.2 2.1e-25 89.1 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Alpha_L_fucos PF01120.17 PVD39018.1 - 2.3e-91 306.9 9.7 7.8e-76 255.8 4.9 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase Fucosidase_C PF16757.5 PVD39018.1 - 3.2e-25 88.5 0.1 6.9e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain LSDAT_euk PF18139.1 PVD39019.1 - 5.1e-73 245.7 0.3 8.9e-73 244.9 0.3 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 PVD39019.1 - 5.8e-27 94.2 1.3 1.8e-26 92.7 1.3 1.8 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote LDcluster4 PF18306.1 PVD39019.1 - 0.0056 16.3 2.0 0.75 9.4 0.1 2.4 2 0 0 2 2 2 2 SLOG cluster4 family DUF1056 PF06341.11 PVD39019.1 - 0.23 11.8 3.7 0.62 10.4 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) K_channel_TID PF07941.11 PVD39020.1 - 0.25 11.8 0.1 0.25 11.8 0.1 1.9 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Mre11_DNA_bind PF04152.14 PVD39021.1 - 8.8e-47 159.6 0.7 8.8e-47 159.6 0.7 2.3 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PVD39021.1 - 2.5e-16 60.8 1.1 4.6e-16 59.9 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PVD39021.1 - 1.3e-06 28.7 0.0 1.2e-05 25.6 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4392 PF14336.6 PVD39021.1 - 0.38 10.2 2.4 0.32 10.4 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) DUF5320 PF17253.2 PVD39021.1 - 0.66 11.1 5.3 1.9 9.6 5.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4586 PF15239.6 PVD39022.1 - 8.6e-80 269.1 10.8 1e-79 268.9 10.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Uso1_p115_head PF04869.14 PVD39023.1 - 1.5e-65 221.4 1.1 6.8e-65 219.2 1.1 2.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 PVD39023.1 - 1.9e-31 107.8 5.6 1.9e-31 107.8 5.6 2.2 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 PVD39023.1 - 1.7e-11 44.6 59.7 2.6e-11 44.0 29.2 4.2 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region C1q PF00386.21 PVD39023.1 - 6.8e-10 39.3 0.0 6.8e-10 39.3 0.0 3.3 4 0 0 4 4 4 1 C1q domain CALCOCO1 PF07888.11 PVD39023.1 - 0.0027 16.6 17.5 0.0027 16.6 17.5 2.7 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 PVD39023.1 - 0.0068 16.8 2.2 0.0068 16.8 2.2 7.0 5 1 2 7 7 6 2 Cell division protein ZapB TMF_TATA_bd PF12325.8 PVD39023.1 - 0.013 15.7 19.1 0.013 15.7 19.1 5.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DNA_repr_REX1B PF14966.6 PVD39023.1 - 0.016 15.9 12.0 0.62 10.8 2.0 3.8 4 0 0 4 4 3 0 DNA repair REX1-B Nup54 PF13874.6 PVD39023.1 - 0.29 11.2 25.4 3.9 7.6 4.3 3.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 KASH_CCD PF14662.6 PVD39023.1 - 1.4 8.7 52.8 3.5 7.4 9.7 3.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF812 PF05667.11 PVD39023.1 - 1.6 7.5 52.0 5.3 5.8 24.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DpnI_C PF17726.1 PVD39023.1 - 2.5 8.3 7.3 0.34 11.1 1.4 2.6 3 0 0 3 3 3 0 Dam-replacing HTH domain Fez1 PF06818.15 PVD39023.1 - 2.5 8.5 47.7 0.55 10.7 25.1 3.4 2 1 1 3 3 3 0 Fez1 Lebercilin PF15619.6 PVD39023.1 - 3.5 7.3 53.2 0.69 9.5 15.8 5.2 2 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 PVD39023.1 - 4.4 6.6 35.2 1.7e+02 1.3 0.0 3.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 PVD39023.1 - 5.2 5.9 58.3 5.4 5.8 9.1 4.7 2 1 1 4 4 4 0 Spc7 kinetochore protein Mre11_DNA_bind PF04152.14 PVD39024.1 - 6.9e-14 52.5 5.5 1.1e-10 42.0 0.0 3.2 3 0 0 3 3 3 2 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PVD39024.1 - 0.027 15.0 0.2 0.049 14.1 0.2 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ESM4 PF15952.5 PVD39024.1 - 0.076 13.4 3.7 0.13 12.6 3.7 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family PMP22_Claudin PF00822.20 PVD39026.1 - 0.0022 17.9 2.9 0.0033 17.3 2.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD39026.1 - 0.018 14.8 7.4 1.1 9.0 7.4 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction 7tm_1 PF00001.21 PVD39027.1 - 0.0011 18.3 1.5 0.0014 18.0 1.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PMP22_Claudin PF00822.20 PVD39028.1 - 0.0046 16.9 2.0 0.0073 16.2 2.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Ank_4 PF13637.6 PVD39029.1 - 7.2e-30 103.0 7.8 5e-12 46.1 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD39029.1 - 1.4e-28 99.2 1.1 7.6e-11 42.5 0.6 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PVD39029.1 - 2.3e-24 85.1 3.3 8.2e-09 35.6 0.1 5.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD39029.1 - 3.6e-24 82.2 3.7 3.1e-05 24.0 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 PVD39029.1 - 8.8e-20 70.2 5.7 1.6e-05 25.1 0.1 6.3 5 1 0 5 5 5 4 Ankyrin repeat La PF05383.17 PVD39030.1 - 4.1e-18 65.2 0.1 8.6e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 PVD39030.1 - 3.9e-17 61.8 0.0 1.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD39030.1 - 7.1e-07 29.2 0.7 0.00014 21.9 0.3 4.4 5 1 0 5 5 5 2 RNA binding motif RF3_C PF16658.5 PVD39030.1 - 0.016 15.0 0.6 0.18 11.7 0.1 2.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Nup35_RRM_2 PF14605.6 PVD39030.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 PVD39031.1 - 5.3e-14 51.8 0.0 1.4e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PVD39031.1 - 2.5e-09 37.1 0.3 2.5e-09 37.1 0.3 5.3 5 1 1 6 6 6 2 RNA binding motif RF3_C PF16658.5 PVD39031.1 - 0.022 14.6 1.1 0.43 10.4 0.1 3.8 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain SANTA PF09133.10 PVD39031.1 - 0.076 13.5 0.1 0.51 10.9 0.1 2.5 1 0 0 1 1 1 0 SANTA (SANT Associated) FERM_M PF00373.18 PVD39031.1 - 0.18 12.2 0.1 0.18 12.2 0.1 3.4 2 2 0 2 2 2 0 FERM central domain Cadherin_3 PF16184.5 PVD39032.1 - 5.5e-211 686.4 40.7 4.3e-26 91.1 0.9 12.7 12 1 0 12 12 12 12 Cadherin-like Calx-beta PF03160.14 PVD39032.1 - 4.1e-53 177.7 5.5 1.9e-12 47.2 0.0 6.1 5 0 0 5 5 5 5 Calx-beta domain VWC PF00093.18 PVD39032.1 - 3e-27 94.7 116.7 1e-07 32.2 16.4 11.1 8 2 1 9 9 9 6 von Willebrand factor type C domain Big_9 PF17963.1 PVD39032.1 - 4.6e-09 36.9 28.5 0.0021 18.7 0.5 9.6 10 0 0 10 10 10 4 Bacterial Ig domain Cadherin_4 PF17803.1 PVD39032.1 - 2.1e-08 34.7 20.7 0.056 14.1 0.0 7.6 7 0 0 7 7 7 3 Bacterial cadherin-like domain Furin-like_2 PF15913.5 PVD39032.1 - 3.7e-05 23.8 15.0 3.7e-05 23.8 15.0 9.9 3 1 7 10 10 10 5 Furin-like repeat, cysteine-rich TILa PF12714.7 PVD39032.1 - 0.0039 17.1 9.7 0.0039 17.1 9.7 8.7 7 1 1 8 8 8 4 TILa domain PLAC PF08686.11 PVD39033.1 - 0.00029 21.5 9.1 0.00063 20.4 9.1 1.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain ADAM_spacer1 PF05986.14 PVD39034.1 - 1.3e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 PVD39034.1 - 1.3e-14 54.4 6.0 1.3e-14 54.4 6.0 4.3 4 0 0 4 4 4 1 ADAM cysteine-rich domain TSP_1 PF00090.19 PVD39034.1 - 4.3e-13 49.3 15.2 3.2e-11 43.3 10.2 4.7 4 0 0 4 4 4 2 Thrombospondin type 1 domain Pep_M12B_propep PF01562.19 PVD39034.1 - 1.2e-05 25.6 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide EphA2_TM PF14575.6 PVD39036.1 - 0.0043 17.9 0.1 0.0075 17.1 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 PVD39036.1 - 0.0069 16.3 3.0 0.01 15.7 3.0 1.2 1 0 0 1 1 1 1 Rifin Stevor PF17410.2 PVD39036.1 - 0.0095 15.5 2.2 0.013 15.0 2.2 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF5385 PF17359.2 PVD39036.1 - 0.01 15.4 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) 7TM_GPCR_Str PF10326.9 PVD39036.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF4381 PF14316.6 PVD39036.1 - 0.026 14.8 0.2 0.036 14.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CD34_antigen PF06365.12 PVD39036.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family MLANA PF14991.6 PVD39036.1 - 0.045 14.0 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A WBP-1 PF11669.8 PVD39036.1 - 0.069 13.8 0.0 0.1 13.3 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Shisa PF13908.6 PVD39036.1 - 0.081 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4446 PF14584.6 PVD39036.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMEM154 PF15102.6 PVD39036.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.8 PVD39036.1 - 0.1 13.3 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4051 PF13260.6 PVD39036.1 - 0.11 12.2 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Orthoreo_P10 PF07204.11 PVD39036.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF515 PF04415.12 PVD39036.1 - 0.17 10.2 0.3 0.21 9.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cyt_c_ox_IV PF12270.8 PVD39036.1 - 2.5 8.2 4.2 24 5.1 4.2 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV Synaptobrevin PF00957.21 PVD39036.1 - 4.3 7.2 5.0 6.8 6.6 5.0 1.3 1 0 0 1 1 1 0 Synaptobrevin MWFE PF15879.5 PVD39036.1 - 8.5 6.6 6.3 39 4.5 6.3 2.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2722 PF10846.8 PVD39040.1 - 1.6e-05 24.1 17.2 1.6e-05 24.1 17.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TERB2 PF15101.6 PVD39040.1 - 0.0018 18.4 12.1 0.0019 18.3 12.1 1.2 1 0 0 1 1 1 1 Telomere-associated protein TERB2 PAP_RNA-bind PF04926.15 PVD39040.1 - 0.0039 16.8 5.0 0.0044 16.7 5.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain OATP PF03137.20 PVD39040.1 - 0.0046 15.3 3.7 0.0052 15.1 3.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 PVD39040.1 - 0.0074 16.3 26.5 0.0084 16.2 26.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 PVD39040.1 - 0.013 15.0 5.2 0.013 14.9 5.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 PVD39040.1 - 0.013 14.3 3.5 0.012 14.4 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med15 PF09606.10 PVD39040.1 - 0.016 14.0 22.4 0.013 14.3 22.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Orf78 PF06024.12 PVD39040.1 - 0.027 14.8 3.0 0.042 14.1 3.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4638 PF15472.6 PVD39040.1 - 0.029 14.1 5.7 0.028 14.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Presenilin PF01080.17 PVD39040.1 - 0.032 13.0 7.7 0.029 13.1 7.7 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 PVD39040.1 - 0.037 13.8 4.6 0.044 13.5 4.6 1.2 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 PVD39040.1 - 0.038 14.0 5.4 0.052 13.6 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal V_ATPase_I PF01496.19 PVD39040.1 - 0.042 11.8 6.4 0.041 11.8 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CemA PF03040.14 PVD39040.1 - 0.052 13.5 2.8 0.072 13.0 2.8 1.2 1 0 0 1 1 1 0 CemA family DUF2828 PF11443.8 PVD39040.1 - 0.054 11.6 6.2 0.056 11.5 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4175 PF13779.6 PVD39040.1 - 0.058 11.3 25.4 0.054 11.4 25.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gti1_Pac2 PF09729.9 PVD39040.1 - 0.08 13.0 4.9 0.086 12.9 4.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 PVD39040.1 - 0.092 12.5 7.2 0.093 12.5 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3464 PF11947.8 PVD39040.1 - 0.094 12.5 11.9 0.21 11.3 9.8 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CobT PF06213.12 PVD39040.1 - 0.096 12.1 12.8 0.13 11.7 12.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DcuA_DcuB PF03605.14 PVD39040.1 - 0.1 11.4 1.2 0.12 11.2 1.2 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4407 PF14362.6 PVD39040.1 - 0.13 11.6 6.8 0.14 11.5 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec62 PF03839.16 PVD39040.1 - 0.15 11.6 3.2 0.15 11.6 3.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.14 PVD39040.1 - 0.16 11.9 15.4 0.21 11.6 15.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Folate_carrier PF01770.18 PVD39040.1 - 0.16 10.6 6.2 0.18 10.5 6.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier HCO3_cotransp PF00955.21 PVD39040.1 - 0.22 10.3 3.9 0.25 10.1 3.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family RBM39linker PF15519.6 PVD39040.1 - 0.23 12.6 12.5 0.12 13.5 10.7 1.5 2 0 0 2 2 1 0 linker between RRM2 and RRM3 domains in RBM39 protein INSIG PF07281.12 PVD39040.1 - 0.23 11.1 1.0 0.37 10.4 1.0 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) PRC2_HTH_1 PF18118.1 PVD39040.1 - 0.36 11.6 6.7 0.61 10.9 6.7 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain MDM10 PF12519.8 PVD39040.1 - 0.38 9.6 8.3 0.45 9.3 8.3 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AUX_IAA PF02309.16 PVD39040.1 - 0.38 10.6 5.8 0.47 10.3 5.8 1.1 1 0 0 1 1 1 0 AUX/IAA family CPSF100_C PF13299.6 PVD39040.1 - 0.39 10.9 6.6 0.53 10.5 6.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 PVD39040.1 - 0.43 10.2 38.4 0.65 9.6 38.4 1.3 1 0 0 1 1 1 0 Spt20 family ALMT PF11744.8 PVD39040.1 - 0.47 9.2 4.5 0.42 9.4 4.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 PVD39040.1 - 0.47 9.1 7.4 0.58 8.8 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RED_N PF07808.13 PVD39040.1 - 0.47 10.0 14.8 0.68 9.5 14.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region PepSY_TM PF03929.16 PVD39040.1 - 0.56 9.8 2.8 0.58 9.8 2.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ABC2_membrane_2 PF12679.7 PVD39040.1 - 0.58 9.4 1.2 0.5 9.6 1.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein K_trans PF02705.16 PVD39040.1 - 0.68 8.4 4.1 0.77 8.2 4.1 1.0 1 0 0 1 1 1 0 K+ potassium transporter EIIBC-GUT_N PF03612.14 PVD39040.1 - 0.7 9.6 9.2 1 9.1 9.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 PVD39040.1 - 0.94 8.5 6.1 1 8.4 6.1 1.1 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 PVD39040.1 - 1 8.5 4.1 1 8.5 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MLANA PF14991.6 PVD39040.1 - 1.1 9.5 4.4 1.8 8.9 4.4 1.3 1 0 0 1 1 1 0 Protein melan-A AIF_C PF14721.6 PVD39040.1 - 1.3 9.4 7.8 2 8.8 7.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 PVD39040.1 - 1.3 8.8 9.9 1.7 8.4 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glt_symporter PF03616.14 PVD39040.1 - 1.4 7.5 2.8 1.6 7.3 2.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4834 PF16118.5 PVD39040.1 - 1.6 9.8 16.6 3.2 8.8 16.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 PVD39040.1 - 2.2 7.1 29.6 2.3 7.0 29.6 1.1 1 0 0 1 1 1 0 Androgen receptor Baculo_PP31 PF05311.11 PVD39040.1 - 2.3 7.6 12.0 3.6 7.0 12.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FHIPEP PF00771.20 PVD39040.1 - 2.4 6.5 6.3 2.8 6.3 6.3 1.1 1 0 0 1 1 1 0 FHIPEP family baeRF_family10 PF18854.1 PVD39040.1 - 2.5 8.4 10.8 11 6.3 10.1 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 HA2 PF04408.23 PVD39040.1 - 2.8 8.2 6.6 4.7 7.5 6.6 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) EMC3_TMCO1 PF01956.16 PVD39040.1 - 2.9 7.6 9.2 2 8.1 8.2 1.3 2 0 0 2 2 1 0 Integral membrane protein EMC3/TMCO1-like Ureide_permease PF07168.11 PVD39040.1 - 3.4 6.3 4.5 4.2 6.0 4.5 1.1 1 0 0 1 1 1 0 Ureide permease Asparaginase_2 PF01112.18 PVD39040.1 - 3.8 6.5 6.4 5.2 6.0 6.4 1.3 1 0 0 1 1 1 0 Asparaginase PigN PF04987.14 PVD39040.1 - 4 6.2 5.2 5.1 5.8 5.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) PAT1 PF09770.9 PVD39040.1 - 5.3 5.2 25.7 5.6 5.1 25.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.6 PVD39040.1 - 5.6 7.5 11.7 11 6.5 11.7 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 eIF-3_zeta PF05091.12 PVD39040.1 - 5.6 5.8 18.2 7.7 5.4 18.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5336 PF17270.2 PVD39040.1 - 6.1 6.5 10.4 8.7 5.9 10.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF1980 PF09323.10 PVD39040.1 - 6.4 6.7 7.9 9.1 6.2 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 PVD39040.1 - 9 5.1 6.7 11 4.9 6.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Rep_fac_C PF08542.11 PVD39041.1 - 2.7e-25 88.6 0.2 4.2e-23 81.5 0.1 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 PVD39041.1 - 3.5e-17 63.1 0.0 7.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PVD39041.1 - 6.8e-16 58.5 0.0 3.5e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 PVD39041.1 - 1.6e-08 34.7 0.0 5.4e-08 33.0 0.0 1.7 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 PVD39041.1 - 1.6e-05 24.8 0.1 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 PVD39041.1 - 1.7e-05 25.0 0.0 4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 PVD39041.1 - 2e-05 24.4 0.0 4.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PVD39041.1 - 5.8e-05 23.4 0.3 0.24 11.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 PVD39041.1 - 0.00012 22.5 0.0 0.00028 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 PVD39041.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 PVD39041.1 - 0.00018 21.3 0.0 0.00045 20.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 PVD39041.1 - 0.00024 21.1 0.0 0.11 12.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 PVD39041.1 - 0.00026 20.2 0.0 0.00046 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PVD39041.1 - 0.00037 20.5 0.0 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PVD39041.1 - 0.0005 20.1 0.1 0.0017 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 PVD39041.1 - 0.001 18.9 0.2 0.031 14.1 0.0 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PVD39041.1 - 0.0011 19.3 0.2 0.084 13.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain TniB PF05621.11 PVD39041.1 - 0.0046 16.4 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 PVD39041.1 - 0.0052 16.5 0.3 0.055 13.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PVD39041.1 - 0.0057 16.1 0.2 0.48 9.8 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 PVD39041.1 - 0.0071 15.8 0.3 0.42 10.0 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein TIP49 PF06068.13 PVD39041.1 - 0.0075 15.5 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 PVD39041.1 - 0.0086 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 PVD39041.1 - 0.029 14.1 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 PVD39041.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.23 PVD39041.1 - 0.11 11.1 0.0 0.25 10.0 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain RNA_helicase PF00910.22 PVD39041.1 - 0.14 12.5 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase 3HCDH_N PF02737.18 PVD39042.1 - 7.6e-62 208.4 2.0 1.1e-61 207.8 2.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PVD39042.1 - 2.9e-26 91.9 0.0 9.5e-26 90.3 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 PVD39042.1 - 4.3e-06 26.2 0.1 6.7e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PVD39042.1 - 8.3e-06 26.3 0.1 1.5e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 PVD39042.1 - 0.00015 22.0 0.4 0.00026 21.2 0.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 PVD39042.1 - 0.00027 20.3 1.7 0.00048 19.5 1.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 PVD39042.1 - 0.00052 19.7 0.2 0.00087 18.9 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PVD39042.1 - 0.0019 18.2 1.0 0.0046 16.9 0.9 1.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 PVD39042.1 - 0.004 17.6 0.3 0.0064 16.9 0.3 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 PVD39042.1 - 0.0049 16.5 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PVD39042.1 - 0.012 14.8 0.2 0.014 14.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.17 PVD39042.1 - 0.015 15.9 2.7 0.062 13.9 2.5 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 PVD39042.1 - 0.025 14.8 0.1 0.085 13.1 0.2 1.8 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 PVD39042.1 - 0.032 14.5 0.6 0.063 13.5 0.6 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain XdhC_C PF13478.6 PVD39042.1 - 0.037 14.5 0.6 0.12 12.9 0.3 2.0 2 1 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 PVD39042.1 - 0.063 12.5 0.2 0.084 12.1 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PVD39042.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ZZ PF00569.17 PVD39043.1 - 8.9e-19 67.0 17.0 1.6e-09 37.4 5.6 2.9 3 0 0 3 3 3 2 Zinc finger, ZZ type ANAPC10 PF03256.16 PVD39043.1 - 2.5e-10 40.3 0.1 5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CUB PF00431.20 PVD39043.1 - 0.0072 16.7 0.2 0.069 13.5 0.1 2.6 2 0 0 2 2 2 1 CUB domain BUD22 PF09073.10 PVD39043.1 - 0.07 12.5 7.5 0.14 11.5 7.5 1.4 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 PVD39043.1 - 0.24 11.6 14.5 0.6 10.3 14.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 C1_2 PF03107.16 PVD39043.1 - 0.27 11.6 19.6 0.018 15.3 3.9 3.0 2 0 0 2 2 2 0 C1 domain TRAP_alpha PF03896.16 PVD39043.1 - 1.1 8.4 5.8 2 7.6 5.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 PVD39043.1 - 2.3 8.0 8.5 5.3 6.8 8.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein E1_dh PF00676.20 PVD39044.1 - 5.2e-82 275.2 0.1 7.6e-82 274.6 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 PVD39044.1 - 1.6e-65 220.1 0.0 2.5e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 PVD39044.1 - 4.6e-52 175.7 0.0 7.6e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 PVD39044.1 - 1.1e-17 63.4 0.5 1.1e-17 63.4 0.5 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 PVD39044.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 IRF PF00605.17 PVD39045.1 - 8.5e-29 99.9 0.1 8.5e-29 99.9 0.1 2.2 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor EF-hand_1 PF00036.32 PVD39046.1 - 1.9e-25 86.5 7.3 1.2e-05 24.5 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 PVD39046.1 - 3.9e-22 76.2 4.2 5.2e-06 26.0 0.2 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 PVD39046.1 - 1.6e-21 76.5 2.0 2.3e-09 37.6 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD39046.1 - 3.6e-18 64.2 4.0 2.7e-05 23.5 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 PVD39046.1 - 5.1e-16 58.3 4.5 5.1e-07 29.4 0.0 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 PVD39046.1 - 0.0027 18.0 0.1 27 5.2 0.1 4.4 4 1 0 4 4 4 0 EF-hand domain GUN4 PF05419.12 PVD39046.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 GUN4-like Scytalone_dh PF02982.14 PVD39046.1 - 0.086 12.6 0.6 0.44 10.3 0.1 2.2 2 1 0 2 2 2 0 Scytalone dehydratase DIX PF00778.17 PVD39047.1 - 3.2e-26 91.0 0.0 6.9e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 PVD39047.1 - 4.7e-23 81.7 0.2 1.8e-22 79.8 0.5 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 PVD39047.1 - 1.5e-09 37.8 0.4 1.5e-09 37.8 0.4 3.0 4 0 0 4 4 4 1 Axin beta-catenin binding domain AXIN1_TNKS_BD PF16646.5 PVD39047.1 - 2.5e-09 38.0 4.0 2.5e-09 38.0 4.0 4.2 3 1 0 3 3 3 1 Axin-1 tankyrase binding domain DUF3135 PF11333.8 PVD39047.1 - 0.15 12.3 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) SNF PF00209.18 PVD39048.1 - 3.2e-162 540.9 36.0 3.7e-138 461.5 22.9 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family FKBP_C PF00254.28 PVD39049.1 - 2.1e-33 114.5 0.0 3e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 PVD39049.1 - 2.1e-09 36.3 1.9 8.4e-05 21.8 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD39049.1 - 3e-07 29.8 0.9 0.016 15.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PVD39049.1 - 3.1e-07 30.7 0.1 6.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PVD39049.1 - 4.1e-07 29.2 2.3 0.0016 17.9 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PVD39049.1 - 0.0079 16.0 0.2 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 PVD39049.1 - 0.025 14.4 0.4 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 PVD39049.1 - 0.042 14.2 0.4 6.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RAMA PF18755.1 PVD39050.1 - 7e-30 103.6 2.0 1.9e-29 102.3 0.4 2.3 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated JAB PF01398.21 PVD39050.1 - 1.5e-10 41.1 0.2 3.7e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PVD39050.1 - 2.2e-05 24.2 1.2 0.00012 21.8 1.3 2.1 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PVD39050.1 - 0.019 15.0 0.2 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) RadC PF04002.15 PVD39050.1 - 0.078 12.9 0.1 0.7 9.9 0.0 2.4 3 0 0 3 3 3 0 RadC-like JAB domain CSN8_PSD8_EIF3K PF10075.9 PVD39051.1 - 2.7e-31 108.5 0.0 3.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RVT_1 PF00078.27 PVD39052.1 - 0.035 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Transpos_assoc PF13963.6 PVD39053.1 - 0.25 11.7 0.3 0.25 11.7 0.3 1.5 2 0 0 2 2 2 0 Transposase-associated domain CD225 PF04505.12 PVD39054.1 - 1.1e-11 44.7 0.4 1.7e-11 44.1 0.4 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF456 PF04306.13 PVD39054.1 - 0.002 18.4 2.4 0.0027 18.0 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF4199 PF13858.6 PVD39054.1 - 0.0027 18.2 0.3 0.0035 17.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF4064 PF13273.6 PVD39054.1 - 0.0029 17.9 1.6 0.015 15.5 2.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Orf78 PF06024.12 PVD39054.1 - 0.014 15.7 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4190 PF13828.6 PVD39054.1 - 0.051 13.3 5.2 0.11 12.3 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) DHHC PF01529.20 PVD39054.1 - 0.069 13.3 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Hanta_nucleocap PF00846.18 PVD39054.1 - 0.083 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein DUF3149 PF11346.8 PVD39054.1 - 7.2 6.3 11.6 13 5.5 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) CD225 PF04505.12 PVD39055.1 - 4e-13 49.3 0.2 5.7e-13 48.8 0.2 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 PVD39055.1 - 0.00021 21.0 3.4 0.046 13.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4190) DUF4199 PF13858.6 PVD39055.1 - 0.049 14.0 0.0 0.06 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF981 PF06168.11 PVD39055.1 - 0.056 13.4 0.3 0.096 12.6 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF5353 PF17304.2 PVD39055.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Innexin PF00876.18 PVD39057.1 - 4.2e-107 358.5 10.9 1.5e-106 356.6 10.9 1.7 1 1 0 1 1 1 1 Innexin Homeobox_KN PF05920.11 PVD39062.1 - 5.7e-17 61.3 0.3 1e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PVD39062.1 - 2.5e-06 27.2 0.9 4.4e-06 26.4 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PVD39062.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez T2SSG PF08334.11 PVD39062.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Herpes_US9 PF06072.11 PVD39063.1 - 0.16 11.9 3.0 6.1 6.8 0.3 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DAO PF01266.24 PVD39068.1 - 5.9e-44 151.1 0.0 8.8e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 PVD39068.1 - 4.8e-41 139.6 0.0 9.1e-41 138.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 PVD39068.1 - 6.3e-11 42.6 0.8 1.7e-10 41.2 0.8 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD39068.1 - 3e-07 29.5 1.0 0.031 13.8 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PVD39068.1 - 6e-06 25.8 0.8 0.0022 17.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain FAD_binding_2 PF00890.24 PVD39068.1 - 0.00024 20.3 0.7 0.00092 18.4 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain EF-hand_8 PF13833.6 PVD39068.1 - 0.00032 20.5 1.2 0.0019 18.0 0.3 2.7 2 1 1 3 3 3 1 EF-hand domain pair GIDA PF01134.22 PVD39068.1 - 0.00058 19.0 0.1 0.33 10.0 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 PVD39068.1 - 0.0011 18.4 0.2 0.0023 17.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_9 PF14658.6 PVD39068.1 - 0.0082 16.5 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain SQS_PSY PF00494.19 PVD39068.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase Pyr_redox_2 PF07992.14 PVD39068.1 - 0.04 13.1 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb4 PF03874.16 PVD39068.1 - 0.79 10.1 4.4 4.1 7.8 0.6 3.4 4 1 0 4 4 4 0 RNA polymerase Rpb4 P4Ha_N PF08336.11 PVD39069.1 - 5.4e-16 58.8 0.1 1.3e-15 57.6 0.1 1.7 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_2 PF07719.17 PVD39069.1 - 0.031 14.4 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat IreB PF06135.12 PVD39070.1 - 0.93 9.7 4.8 28 5.0 1.3 3.0 1 1 1 2 2 2 0 IreB regulatory phosphoprotein M16C_assoc PF08367.11 PVD39072.1 - 5.8e-77 258.2 0.7 9.6e-77 257.5 0.1 1.7 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PVD39072.1 - 6.7e-31 107.7 0.0 1.5e-21 77.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PVD39072.1 - 3.3e-09 36.9 0.2 4.3e-07 30.0 0.0 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Ank_2 PF12796.7 PVD39073.1 - 7.8e-52 173.8 14.3 1.5e-17 64.0 0.9 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PVD39073.1 - 8.5e-30 101.9 11.4 3.3e-06 27.3 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PVD39073.1 - 6.7e-28 96.7 4.0 5.1e-09 36.5 0.1 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD39073.1 - 2e-25 88.5 7.3 1.4e-09 38.0 0.2 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD39073.1 - 1.1e-23 80.7 7.3 0.00025 21.3 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat SOCS_box PF07525.16 PVD39073.1 - 1e-07 32.2 6.7 2.7e-07 30.8 6.7 1.8 1 0 0 1 1 1 1 SOCS box DFRP_C PF16543.5 PVD39074.1 - 1.5e-23 83.1 3.5 1.5e-23 83.1 3.5 4.1 4 1 1 5 5 5 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 PVD39074.1 - 5.2e-09 36.8 15.1 6.2e-07 30.1 4.2 3.3 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 PVD39074.1 - 8.8e-09 35.0 7.0 3.8e-06 26.6 1.0 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PVD39074.1 - 1.3e-08 34.6 16.4 2.5e-06 27.3 6.3 2.9 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 PVD39074.1 - 2.6e-07 30.4 7.3 5.3e-07 29.4 1.1 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PVD39074.1 - 0.00054 20.3 11.1 0.014 15.9 2.7 2.6 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HV_small_capsid PF17086.5 PVD39074.1 - 0.0099 16.1 0.3 0.056 13.7 0.3 2.3 1 0 0 1 1 1 1 Small capsid protein of Herpesviridae zf-CCCH_3 PF15663.5 PVD39074.1 - 0.02 15.1 8.1 0.14 12.4 1.3 3.1 3 1 0 3 3 3 0 Zinc-finger containing family WD40 PF00400.32 PVD39075.1 - 0.00027 21.7 0.2 0.66 11.0 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Phage_GPO PF05929.11 PVD39076.1 - 0.11 12.0 3.4 0.17 11.5 3.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CDC45 PF02724.14 PVD39077.1 - 0.12 10.7 4.5 0.15 10.3 2.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Nop53 PF07767.11 PVD39077.1 - 0.21 11.0 14.5 0.37 10.1 14.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 PVD39077.1 - 4.3 5.3 8.5 12 3.8 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi RR_TM4-6 PF06459.12 PVD39077.1 - 6.9 6.4 12.8 0.37 10.6 6.7 1.9 2 1 0 2 2 2 0 Ryanodine Receptor TM 4-6 zf-C4 PF00105.18 PVD39079.1 - 5.2e-31 106.9 15.3 1.6e-30 105.3 15.3 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD39079.1 - 4e-24 85.3 0.0 1.1e-23 83.9 0.0 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SOG2 PF10428.9 PVD39081.1 - 0.45 9.6 15.1 0.6 9.2 15.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Trypsin PF00089.26 PVD39082.1 - 0.0041 17.0 3.3 0.0097 15.7 3.0 1.7 1 1 1 2 2 2 1 Trypsin DUF3446 PF11928.8 PVD39082.1 - 0.49 10.7 16.7 0.09 13.1 6.4 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain CWC25 PF12542.8 PVD39083.1 - 1.3e-15 58.1 0.2 1.3e-15 58.1 0.2 5.2 2 1 0 2 2 2 1 Pre-mRNA splicing factor Gasdermin PF04598.12 PVD39084.1 - 6e-25 88.1 0.1 2.4e-24 86.1 0.1 1.9 1 1 0 1 1 1 1 Gasdermin pore forming domain HCO3_cotransp PF00955.21 PVD39085.1 - 5.8e-208 691.8 14.0 4.8e-205 682.2 14.0 2.3 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 PVD39085.1 - 8.2e-84 281.6 2.9 8.6e-83 278.2 0.0 2.8 2 1 0 2 2 2 1 Band 3 cytoplasmic domain Sulfate_transp PF00916.20 PVD39085.1 - 0.00033 19.6 5.6 0.00033 19.6 5.6 2.6 1 1 2 3 3 3 1 Sulfate permease family EVI2A PF05399.11 PVD39085.1 - 0.0058 16.3 7.0 0.078 12.6 0.1 2.4 2 0 0 2 2 2 2 Ectropic viral integration site 2A protein (EVI2A) DapH_N PF08503.10 PVD39085.1 - 0.056 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Band_3_cyto PF07565.13 PVD39087.1 - 0.00026 20.9 0.1 0.00048 20.0 0.0 1.4 2 0 0 2 2 2 1 Band 3 cytoplasmic domain UPF0561 PF10573.9 PVD39087.1 - 0.074 13.2 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 HCO3_cotransp PF00955.21 PVD39088.1 - 1.5e-211 703.7 10.7 9.6e-211 701.0 10.7 1.9 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 PVD39088.1 - 2.6e-25 89.8 3.4 3.3e-12 46.8 0.1 2.5 2 1 1 3 3 3 2 Band 3 cytoplasmic domain Glyoxalase_2 PF12681.7 PVD39088.1 - 0.085 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Laminin_G_3 PF13385.6 PVD39089.1 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chitin_bind_4 PF00379.23 PVD39089.1 - 0.17 12.4 9.5 20 5.8 0.0 5.4 5 1 0 5 5 5 0 Insect cuticle protein VWA PF00092.28 PVD39090.1 - 5e-68 228.8 0.5 1.3e-33 116.7 0.1 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD39090.1 - 6.7e-30 103.9 0.0 3.6e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 PVD39090.1 - 7e-06 26.1 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Copine PF07002.16 PVD39090.1 - 0.00027 20.4 0.6 0.1 12.0 0.1 2.2 2 0 0 2 2 2 2 Copine CBM_14 PF01607.24 PVD39090.1 - 0.00086 19.4 17.8 0.0016 18.6 3.2 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain VWA_CoxE PF05762.14 PVD39090.1 - 0.0016 17.8 0.1 0.0082 15.6 0.0 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein UQ_con PF00179.26 PVD39093.1 - 7.1e-31 106.7 0.0 7.8e-31 106.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Btz PF09405.10 PVD39094.1 - 1.2e-17 64.4 10.0 1.2e-17 64.4 10.0 4.6 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding NHL PF01436.21 PVD39095.1 - 3e-09 36.5 3.2 0.0064 16.5 0.1 5.6 6 0 0 6 6 6 3 NHL repeat zf-B_box PF00643.24 PVD39095.1 - 0.00037 20.6 9.1 0.00037 20.6 9.1 4.9 4 1 0 4 4 4 2 B-box zinc finger FYVE_2 PF02318.16 PVD39095.1 - 0.026 14.7 34.1 0.032 14.4 4.5 4.0 1 1 2 3 3 3 0 FYVE-type zinc finger Methyltransf_16 PF10294.9 PVD39096.1 - 6.3e-29 100.9 0.0 8.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 PVD39096.1 - 0.034 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF5524 PF17662.1 PVD39097.1 - 8.3e-22 77.9 1.6 1.1e-21 77.5 1.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5524) SGIII PF15467.6 PVD39098.1 - 0.0026 17.1 2.4 0.0028 17.0 2.4 1.0 1 0 0 1 1 1 1 Secretogranin-3 TP53IP5 PF15331.6 PVD39098.1 - 0.27 11.4 4.6 0.32 11.1 4.6 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Menin PF05053.13 PVD39098.1 - 1.6 7.0 4.3 1.7 6.9 4.3 1.0 1 0 0 1 1 1 0 Menin WRW PF10206.9 PVD39099.1 - 2.5e-23 82.4 0.1 2.7e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Aa_trans PF01490.18 PVD39100.1 - 8.3e-52 176.3 37.5 1.2e-51 175.7 37.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4131 PF13567.6 PVD39100.1 - 2.1 8.0 0.0 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Branch PF02485.21 PVD39101.1 - 2.3e-32 112.4 0.8 6.5e-32 111.0 0.8 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme RRM_3 PF08777.11 PVD39102.1 - 1.2e-22 79.9 8.1 2.5e-22 78.8 1.4 3.0 2 1 0 2 2 2 1 RNA binding motif La PF05383.17 PVD39102.1 - 4.4e-22 77.9 0.1 1.3e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 PVD39102.1 - 3.6e-13 49.1 0.9 4.3e-07 29.7 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PVD39102.1 - 0.00027 20.8 0.1 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 RL domain RRM_7 PF16367.5 PVD39102.1 - 0.00045 20.3 0.6 0.19 11.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD39102.1 - 0.011 15.7 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 PVD39102.1 - 0.021 14.6 0.1 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF4651 PF15513.6 PVD39102.1 - 0.067 13.0 0.0 7.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) DUF1882 PF08966.11 PVD39102.1 - 0.32 11.3 0.2 0.32 11.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1882) Band_7 PF01145.25 PVD39103.1 - 9.6e-07 29.0 0.0 1.7e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_24 PF13578.6 PVD39103.1 - 0.19 12.8 0.3 51 5.0 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain DUF3853 PF12964.7 PVD39114.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) TCP PF03634.13 PVD39114.1 - 3.9 8.0 9.5 1.6 9.3 6.2 1.8 2 0 0 2 2 2 0 TCP family transcription factor Homeodomain PF00046.29 PVD39118.1 - 1.7e-22 79.0 8.5 2.8e-22 78.3 8.5 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 PVD39118.1 - 2.4e-07 30.4 1.0 5.5e-07 29.2 1.0 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 PVD39118.1 - 0.0024 17.7 0.6 0.0024 17.7 0.6 1.8 2 0 0 2 2 2 1 Homeobox KN domain DUF3108 PF11306.8 PVD39118.1 - 0.079 12.9 0.6 0.12 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) SPX PF03105.19 PVD39118.1 - 0.69 9.8 12.9 0.99 9.3 12.9 1.3 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 PVD39118.1 - 1.9 6.9 11.6 2.5 6.5 11.6 1.1 1 0 0 1 1 1 0 Macoilin family Forkhead_N PF08430.12 PVD39118.1 - 7.1 7.2 29.2 0.1 13.2 7.1 2.4 2 0 0 2 2 2 0 Forkhead N-terminal region SR-25 PF10500.9 PVD39123.1 - 0.1 12.2 6.1 0.12 12.0 6.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cadherin PF00028.17 PVD39124.1 - 1.9e-14 53.9 0.6 1.6e-11 44.5 0.1 2.5 1 1 1 2 2 2 2 Cadherin domain Cadherin-like PF12733.7 PVD39124.1 - 0.034 14.7 0.8 5.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Cadherin_2 PF08266.12 PVD39124.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like DUF2808 PF10989.8 PVD39124.1 - 0.076 13.0 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Sulfotransfer_3 PF13469.6 PVD39125.1 - 1.4e-05 25.6 0.1 4.2e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PVD39125.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Claudin_2 PF13903.6 PVD39125.1 - 0.041 13.6 12.2 2.3 7.9 12.2 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF782 PF05614.11 PVD39125.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) L_HMGIC_fpl PF10242.9 PVD39125.1 - 2.8 8.1 6.8 1 9.6 0.8 2.3 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Peptidase_C10 PF01640.17 PVD39126.1 - 0.0021 18.4 0.2 0.015 15.6 0.2 2.0 1 1 0 1 1 1 1 Peptidase C10 family DUF308 PF03729.13 PVD39128.1 - 0.0086 16.4 2.8 0.0086 16.4 2.8 1.4 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) Claudin_3 PF06653.11 PVD39129.1 - 0.02 14.8 4.7 0.054 13.4 4.7 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TMEM37 PF15108.6 PVD39129.1 - 0.079 12.8 5.3 0.16 11.8 5.1 1.8 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Claudin_2 PF13903.6 PVD39129.1 - 0.6 9.8 20.2 1.1 9.0 0.2 3.4 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction SufE PF02657.15 PVD39130.1 - 0.0062 16.4 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain Claudin_2 PF13903.6 PVD39130.1 - 0.089 12.5 3.6 4.5 7.0 0.1 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PVD39130.1 - 0.11 12.5 2.3 0.9 9.5 2.3 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PHP_C PF13263.6 PVD39130.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 PHP-associated TMEM37 PF15108.6 PVD39131.1 - 0.0031 17.4 2.9 0.0047 16.8 2.9 1.2 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family Claudin_3 PF06653.11 PVD39131.1 - 0.065 13.2 0.0 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Tight junction protein, Claudin-like MFS_1 PF07690.16 PVD39132.1 - 1.3e-14 53.9 33.8 2.1e-11 43.3 20.7 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 PVD39132.1 - 1.2e-12 47.1 18.1 4.2e-06 25.6 0.3 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 PVD39132.1 - 8.2e-11 41.4 5.7 1.4e-10 40.6 5.7 1.3 1 0 0 1 1 1 1 MFS_1 like family RRM_4 PF10598.9 PVD39132.1 - 1.3 9.4 3.6 7.1 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif of the spliceosomal PrP8 FYVE PF01363.21 PVD39133.1 - 2.2e-18 66.1 13.5 4.9e-18 65.0 13.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 PVD39133.1 - 1.3e-06 28.2 15.7 0.43 10.7 0.1 7.3 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.7 PVD39133.1 - 0.00025 21.1 0.8 0.0017 18.3 0.8 2.2 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus DUF3730 PF12530.8 PVD39133.1 - 0.0027 17.3 1.1 0.033 13.8 0.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) Coatomer_E PF04733.14 PVD39133.1 - 0.1 12.0 0.1 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit CTNNBL PF08216.11 PVD39133.1 - 0.18 12.0 0.0 44 4.3 0.0 3.2 2 1 1 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear FYVE_2 PF02318.16 PVD39133.1 - 0.61 10.3 11.4 1.4 9.1 11.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PLDc_2 PF13091.6 PVD39134.1 - 1.7e-11 44.1 0.0 3.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PVD39134.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.6 3 0 0 3 3 3 0 Phospholipase D Active site motif DHC_N1 PF08385.12 PVD39135.1 - 4.7e-184 613.1 9.5 4.7e-184 613.1 9.5 4.2 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 PVD39135.1 - 2.7e-180 598.8 11.7 6.1e-180 597.7 11.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 PVD39135.1 - 1.3e-155 517.4 0.0 2.8e-153 509.7 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PVD39135.1 - 7.8e-126 420.4 20.1 7.8e-126 420.4 20.1 5.3 6 1 1 7 7 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PVD39135.1 - 4e-100 335.0 0.1 1.4e-99 333.2 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PVD39135.1 - 2e-96 322.3 0.0 1.5e-95 319.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PVD39135.1 - 1.6e-84 282.5 0.1 1.6e-84 282.5 0.1 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PVD39135.1 - 1.4e-74 249.5 0.4 2.7e-69 232.3 0.1 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PVD39135.1 - 3.8e-54 182.9 0.0 1.5e-53 181.0 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PVD39135.1 - 1.3e-45 153.6 4.9 2.9e-44 149.3 0.1 3.6 3 0 0 3 3 2 1 AAA+ lid domain Dynein_heavy PF03028.15 PVD39135.1 - 2.3e-40 137.4 0.0 2.4e-37 127.6 0.0 4.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PVD39135.1 - 1.4e-28 99.6 1.0 1.1e-27 96.6 1.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PVD39135.1 - 4e-23 81.9 0.0 1.7e-10 41.1 0.0 6.0 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PVD39135.1 - 1e-07 32.3 0.6 0.094 13.0 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 PVD39135.1 - 2.6e-07 31.2 0.0 0.21 12.0 0.0 4.9 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 PVD39135.1 - 2.8e-05 24.5 0.1 0.89 10.0 0.0 4.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PVD39135.1 - 0.00012 21.9 0.7 2 8.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 PVD39135.1 - 0.0011 18.6 0.0 4.3 7.0 0.0 3.5 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 PVD39135.1 - 0.0017 18.9 4.2 1.3 9.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain AAA_19 PF13245.6 PVD39135.1 - 0.0035 17.7 0.2 7.1 7.0 0.0 4.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PVD39135.1 - 0.0037 17.2 0.0 0.24 11.3 0.0 3.3 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 PVD39135.1 - 0.0062 16.9 0.5 33 4.9 0.0 4.5 4 0 0 4 4 3 0 RNA helicase T2SSE PF00437.20 PVD39135.1 - 0.0089 15.1 0.0 0.59 9.1 0.0 3.4 4 0 0 4 4 3 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PVD39135.1 - 0.021 14.8 0.0 8.4 6.3 0.0 3.9 3 0 0 3 3 3 0 RsgA GTPase PhoH PF02562.16 PVD39135.1 - 0.022 14.2 0.5 3.5 7.0 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein TsaE PF02367.17 PVD39135.1 - 0.023 14.7 1.6 4.5 7.3 0.0 3.8 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 PVD39135.1 - 0.033 14.3 0.1 18 5.4 0.0 3.9 3 0 0 3 3 2 0 Sigma-54 interaction domain Roc PF08477.13 PVD39135.1 - 0.045 14.0 0.0 3.8 7.7 0.0 3.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 PVD39135.1 - 0.058 13.1 0.0 1.3 8.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 PVD39135.1 - 0.084 12.6 0.2 87 3.0 0.1 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PVD39135.1 - 0.18 12.3 3.0 27 5.3 0.0 4.9 5 0 0 5 5 3 0 ABC transporter PduV-EutP PF10662.9 PVD39135.1 - 0.23 11.2 2.1 13 5.6 0.0 3.7 5 0 0 5 5 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 PVD39135.1 - 0.34 10.6 3.6 0.77 9.5 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein NPV_P10 PF05531.12 PVD39135.1 - 2.4 8.7 15.3 4.1 7.9 0.1 5.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF4988 PF16378.5 PVD39135.1 - 8.1 6.1 6.9 0.89 9.2 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function Chromo PF00385.24 PVD39137.1 - 7.8e-14 51.3 0.5 1.5e-13 50.4 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 PVD39137.1 - 6.7e-09 35.3 1.9 2e-08 33.8 1.9 1.8 1 0 0 1 1 1 1 CBX family C-terminal motif LAS2 PF15792.5 PVD39137.1 - 0.014 15.9 5.0 0.021 15.4 0.3 2.8 2 0 0 2 2 2 0 Lung adenoma susceptibility protein 2 Mtf2_C PF14061.6 PVD39137.1 - 0.058 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 adh_short PF00106.25 PVD39138.1 - 1.2e-32 113.0 0.4 3.4e-20 72.3 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PVD39138.1 - 1.8e-19 70.2 0.2 4.7e-14 52.5 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD39138.1 - 0.00032 20.7 0.7 0.19 11.6 0.1 2.3 1 1 1 2 2 2 2 KR domain DUF1776 PF08643.10 PVD39138.1 - 0.00035 20.1 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 PVD39138.1 - 0.06 12.5 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 PVD39138.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain wnt PF00110.19 PVD39139.1 - 6.4e-40 137.7 20.7 1.5e-39 136.4 20.7 1.5 1 1 0 1 1 1 1 wnt family Peptidase_M1 PF01433.20 PVD39140.1 - 9.1e-85 283.6 3.7 1.2e-84 283.3 2.4 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 PVD39140.1 - 4e-75 253.3 1.9 6.2e-75 252.7 1.9 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PVD39141.1 - 1.7e-31 109.9 0.1 2.1e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SapB_1 PF05184.15 PVD39142.1 - 2.1e-48 161.8 49.8 1e-11 44.6 1.8 9.1 8 1 0 8 8 8 6 Saposin-like type B, region 1 SapB_2 PF03489.17 PVD39142.1 - 1.2e-33 114.8 22.4 1.9e-08 34.3 0.1 7.8 7 0 0 7 7 7 6 Saposin-like type B, region 2 BP28CT PF08146.12 PVD39142.1 - 6.5e-06 26.1 0.0 8.9 6.1 0.0 5.2 2 1 3 5 5 5 2 BP28CT (NUC211) domain Spore_YunB PF09560.10 PVD39142.1 - 0.00011 22.2 0.0 12 6.0 0.0 4.3 4 0 0 4 4 4 1 Sporulation protein YunB (Spo_YunB) HTH_17 PF12728.7 PVD39142.1 - 0.16 12.2 0.1 25 5.2 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2889 PF11136.8 PVD39142.1 - 0.17 12.2 9.8 0.29 11.5 0.1 4.3 4 1 0 5 5 5 0 Protein of unknown function (DUF2889) Cas_CXXC_CXXC PF09706.10 PVD39142.1 - 0.25 11.6 8.8 43 4.4 0.0 5.6 5 0 0 5 5 5 0 CRISPR-associated protein (Cas_CXXC_CXXC) Thioredoxin_3 PF13192.6 PVD39142.1 - 0.84 9.7 18.6 7.8 6.6 0.3 6.2 6 0 0 6 6 6 0 Thioredoxin domain TIR PF01582.20 PVD39143.1 - 4.9e-44 150.2 0.7 2.8e-22 79.4 0.2 2.2 2 0 0 2 2 2 2 TIR domain TIR_2 PF13676.6 PVD39143.1 - 1.7e-34 119.0 2.5 1.7e-16 60.8 0.2 2.5 2 0 0 2 2 2 2 TIR domain LRR_8 PF13855.6 PVD39143.1 - 8.8e-31 105.5 15.9 4e-08 32.9 0.7 7.8 5 2 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PVD39143.1 - 7.3e-15 54.9 18.7 0.00029 21.2 0.0 7.1 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) DUF1863 PF08937.11 PVD39143.1 - 1.7e-09 38.1 0.0 0.0025 18.1 0.0 3.4 2 2 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) LRR_5 PF13306.6 PVD39143.1 - 1.1e-08 35.1 2.5 0.001 19.1 0.4 3.6 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PVD39143.1 - 2.2e-07 30.5 7.2 8 7.4 0.0 8.7 9 0 0 9 9 8 1 Leucine Rich Repeat LRR_9 PF14580.6 PVD39143.1 - 6.5e-07 29.0 1.8 0.095 12.2 0.0 4.2 2 1 1 4 4 4 2 Leucine-rich repeat TPKR_C2 PF16920.5 PVD39143.1 - 0.016 15.3 0.7 0.11 12.6 0.8 2.4 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 PVD39143.1 - 0.17 12.0 9.0 46 4.4 0.0 6.4 8 0 0 8 8 7 0 Leucine Rich repeat DUF4734 PF15881.5 PVD39143.1 - 0.63 10.2 5.2 11 6.2 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) LRR_8 PF13855.6 PVD39144.1 - 1.3e-32 111.3 40.9 4.4e-11 42.4 0.0 8.3 5 2 4 9 9 9 8 Leucine rich repeat LRR_5 PF13306.6 PVD39144.1 - 3.2e-13 49.8 3.0 5.7e-05 23.1 0.1 3.5 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD39144.1 - 4.4e-13 49.2 34.3 0.0023 18.3 0.0 9.3 3 2 7 11 11 11 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD39144.1 - 6.2e-07 29.1 2.9 0.12 11.9 0.2 3.8 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 PVD39144.1 - 0.00014 22.0 36.6 1.2 10.0 0.2 10.2 12 0 0 12 12 12 4 Leucine Rich Repeat TPKR_C2 PF16920.5 PVD39144.1 - 0.0009 19.3 4.3 0.0012 18.9 2.5 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_8 PF13855.6 PVD39145.1 - 1.3e-33 114.5 46.4 5.9e-12 45.2 8.2 8.0 5 2 3 8 8 8 8 Leucine rich repeat TIR PF01582.20 PVD39145.1 - 3.4e-21 75.8 0.1 5.7e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 PVD39145.1 - 1.2e-17 63.7 37.0 0.0012 19.2 2.3 8.4 3 1 5 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 PVD39145.1 - 1.6e-16 61.0 0.1 3.3e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD39145.1 - 1.5e-09 37.9 7.1 0.0002 21.3 0.5 3.5 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PVD39145.1 - 2.2e-06 27.3 7.7 0.37 10.3 0.3 4.3 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 PVD39145.1 - 7.5e-06 25.8 36.7 1.7 9.5 0.2 10.7 11 0 0 11 11 11 2 Leucine Rich Repeat TPKR_C2 PF16920.5 PVD39145.1 - 0.0033 17.5 2.6 0.0098 16.0 2.6 1.9 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain DUF1863 PF08937.11 PVD39145.1 - 0.016 15.5 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TIR PF01582.20 PVD39146.1 - 1.9e-21 76.6 0.2 3.6e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD39146.1 - 7.3e-18 64.1 19.3 4.1e-12 45.7 4.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat TIR_2 PF13676.6 PVD39146.1 - 8.6e-18 65.1 0.2 1.5e-17 64.3 0.2 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD39146.1 - 1.4e-05 25.1 0.7 2.7e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DUF1863 PF08937.11 PVD39146.1 - 4.5e-05 23.8 0.0 0.00046 20.5 0.0 2.2 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 PVD39146.1 - 0.00013 22.3 1.2 0.00013 22.3 1.2 4.5 2 2 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD39146.1 - 0.012 15.1 0.9 0.021 14.3 0.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeat DC_STAMP PF07782.13 PVD39146.1 - 0.027 14.3 0.3 0.04 13.7 0.3 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein DUF202 PF02656.15 PVD39146.1 - 0.09 13.2 0.5 0.19 12.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) RIFIN PF02009.16 PVD39146.1 - 0.74 9.6 2.1 1.2 9.0 2.1 1.2 1 0 0 1 1 1 0 Rifin LRR_1 PF00560.33 PVD39146.1 - 1.1 10.1 16.9 2.9 8.8 0.2 5.3 3 1 0 3 3 3 0 Leucine Rich Repeat TIR PF01582.20 PVD39147.1 - 4.7e-22 78.6 0.1 8.7e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 PVD39147.1 - 5.1e-18 64.6 46.0 1.8e-11 43.6 5.2 6.0 4 1 2 6 6 6 5 Leucine rich repeat TIR_2 PF13676.6 PVD39147.1 - 5.5e-16 59.2 0.1 1.1e-15 58.3 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 PVD39147.1 - 5.4e-08 32.9 6.9 5.5e-05 23.1 0.5 3.1 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PVD39147.1 - 4.1e-05 23.9 13.0 7.6e-05 23.0 3.5 6.7 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD39147.1 - 0.0031 17.0 11.6 0.074 12.5 0.9 2.8 1 1 3 4 4 4 3 Leucine-rich repeat DUF1863 PF08937.11 PVD39147.1 - 0.0036 17.6 0.0 0.014 15.7 0.0 1.9 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_8 PF13855.6 PVD39148.1 - 2.2e-07 30.5 0.2 0.0023 17.7 0.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD39148.1 - 0.00016 22.0 0.1 0.00016 22.0 0.1 3.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) TPKR_C2 PF16920.5 PVD39148.1 - 0.00039 20.5 0.9 0.0012 18.9 0.9 1.9 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 PVD39148.1 - 2 9.3 11.2 20 6.2 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 PVD39149.1 - 1.6e-10 40.6 2.4 5.1e-10 39.0 2.4 1.8 1 1 0 1 1 1 1 Leucine rich repeat TIR PF01582.20 PVD39149.1 - 4.3e-07 29.9 0.1 8.6e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 PVD39149.1 - 4.2e-05 24.1 0.0 9.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 PVD39149.1 - 0.00037 20.6 4.3 2.3 9.1 0.2 4.3 3 0 0 3 3 3 2 Leucine Rich Repeat TPKR_C2 PF16920.5 PVD39149.1 - 0.00091 19.3 0.5 0.0026 17.9 0.5 1.9 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_4 PF12799.7 PVD39149.1 - 0.012 16.0 0.5 0.012 16.0 0.5 2.8 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PVD39149.1 - 0.061 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF4808 PF16066.5 PVD39149.1 - 0.11 13.1 0.5 0.19 12.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) LRRNT PF01462.18 PVD39149.1 - 1 9.1 5.7 1.9 8.2 0.8 3.4 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain TUDOR PF00567.24 PVD39150.1 - 2.2e-24 85.8 0.6 7.6e-24 84.1 0.1 2.2 2 0 0 2 2 2 1 Tudor domain Pkinase PF00069.25 PVD39150.1 - 2.1e-11 43.7 0.0 9.7e-11 41.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39150.1 - 2e-05 24.0 0.0 4.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Agenet PF05641.12 PVD39150.1 - 0.001 19.5 0.1 0.0033 17.8 0.1 1.9 1 0 0 1 1 1 1 Agenet domain AcylCoA_dehyd_C PF12186.8 PVD39150.1 - 0.0078 16.3 0.5 8.4 6.6 0.0 3.5 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase C terminal DUF4537 PF15057.6 PVD39150.1 - 0.0087 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF4164 PF13747.6 PVD39150.1 - 0.23 11.8 7.8 2.9 8.2 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CSN5_C PF18323.1 PVD39150.1 - 4.3 8.3 6.2 24 5.9 0.3 3.3 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Lyase_1 PF00206.20 PVD39151.1 - 6e-22 78.4 0.0 9.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 PVD39151.1 - 6.3e-15 55.5 0.0 3.1e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 PVD39151.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Talin_middle PF09141.10 PVD39151.1 - 0.025 14.6 0.3 16 5.5 0.1 3.3 3 1 0 3 3 3 0 Talin, middle domain Homeodomain PF00046.29 PVD39152.1 - 1.5e-23 82.4 2.9 4.7e-23 80.8 3.2 1.8 2 0 0 2 2 2 1 Homeodomain adh_short PF00106.25 PVD39153.1 - 2.2e-24 86.0 0.0 3.7e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PVD39153.1 - 4.7e-15 55.8 0.0 1.1e-14 54.5 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PVD39153.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain IKBKB_SDD PF18397.1 PVD39154.1 - 3e-65 220.3 9.6 4.8e-65 219.6 9.6 1.3 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 PVD39154.1 - 6.2e-53 179.8 0.0 2.7e-52 177.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39154.1 - 1.3e-33 116.4 0.2 5.8e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PVD39154.1 - 6.3e-05 21.9 0.0 0.00015 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PVD39154.1 - 0.0013 18.1 0.3 0.0044 16.4 0.3 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PVD39154.1 - 0.0055 16.0 0.0 0.056 12.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Synaptobrevin PF00957.21 PVD39154.1 - 0.015 15.0 0.5 0.89 9.4 0.0 2.5 2 0 0 2 2 2 0 Synaptobrevin TBK1_ULD PF18396.1 PVD39154.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain APH PF01636.23 PVD39154.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin_16 PF18569.1 PVD39155.1 - 4.5e-25 87.6 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C_6 PF17171.4 PVD39155.1 - 4.3e-06 26.4 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PVD39155.1 - 0.00031 20.7 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PVD39155.1 - 0.0024 18.0 0.0 0.0079 16.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos_2 PF12850.7 PVD39155.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GST_C_3 PF14497.6 PVD39155.1 - 0.092 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PHD PF00628.29 PVD39156.1 - 9e-26 89.5 43.1 5.4e-09 35.8 7.3 3.6 3 0 0 3 3 3 3 PHD-finger Bromodomain PF00439.25 PVD39156.1 - 8.7e-24 83.4 0.1 1.8e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 PVD39156.1 - 1.9e-16 60.1 0.6 5.6e-16 58.6 0.6 1.9 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 PVD39156.1 - 4.2e-05 24.0 3.7 4.2e-05 24.0 3.7 5.0 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 PVD39156.1 - 0.00016 21.1 0.0 0.0004 19.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF4428 PF14471.6 PVD39156.1 - 0.26 11.2 3.4 14 5.7 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) PHD_2 PF13831.6 PVD39156.1 - 1.1 8.9 25.1 1.6 8.4 2.2 3.6 3 0 0 3 3 3 0 PHD-finger PIG-X PF08320.12 PVD39157.1 - 1.9e-32 112.9 0.2 2.9e-32 112.3 0.2 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 WD40 PF00400.32 PVD39157.1 - 5.5e-22 77.7 8.3 0.041 14.8 0.0 9.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD39157.1 - 9e-05 22.7 5.7 4.9 7.5 0.0 6.4 2 2 6 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 PVD39157.1 - 0.0027 17.3 0.3 0.0089 15.6 0.3 1.9 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Nucleoporin_N PF08801.11 PVD39157.1 - 0.013 14.3 0.0 1.3 7.7 0.0 3.2 2 2 1 4 4 4 0 Nup133 N terminal like Kelch_6 PF13964.6 PVD39157.1 - 0.03 14.6 4.5 9.3 6.7 0.0 5.8 7 0 0 7 7 7 0 Kelch motif Forkhead PF00250.18 PVD39158.1 - 6.4e-41 138.5 0.2 1e-40 137.8 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 PVD39158.1 - 4.3e-06 27.0 0.0 8.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 PVD39158.1 - 0.042 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family NICE-1 PF15845.5 PVD39158.1 - 0.62 10.9 4.7 6.4 7.6 0.3 2.8 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Ala_racemase_N PF01168.20 PVD39159.1 - 2.1e-54 184.5 0.0 3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 PVD39159.1 - 4.7e-27 94.3 0.0 8.5e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Cupin_8 PF13621.6 PVD39159.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Cupin-like domain DDE_Tnp_1_assoc PF13808.6 PVD39159.1 - 0.69 10.0 2.5 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-associated His_Phos_2 PF00328.22 PVD39160.1 - 8.8e-27 94.4 0.1 1.4e-26 93.8 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rrn6 PF10214.9 PVD39160.1 - 0.083 11.4 0.0 0.098 11.1 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor His_Phos_1 PF00300.22 PVD39160.1 - 0.087 12.5 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF4924 PF16271.5 PVD39160.1 - 0.11 12.5 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4924) APS_kinase PF01583.20 PVD39161.1 - 3.1e-70 235.1 0.0 4.8e-70 234.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 PVD39161.1 - 4.7e-68 228.8 0.0 6.5e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PVD39161.1 - 2.4e-49 167.1 0.0 5.5e-49 165.9 0.0 1.6 2 0 0 2 2 2 1 PUA-like domain AAA_33 PF13671.6 PVD39161.1 - 9.9e-05 22.5 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PVD39161.1 - 0.00071 20.1 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 PVD39161.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 PVD39161.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CbiA PF01656.23 PVD39161.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 PVD39161.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase PEPCK_ATP PF01293.20 PVD39161.1 - 0.23 10.1 0.2 0.45 9.1 0.1 1.4 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase ANAPC4_WD40 PF12894.7 PVD39162.1 - 7e-05 23.1 0.0 0.0031 17.8 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PVD39162.1 - 0.013 16.4 0.3 0.013 16.4 0.3 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat CNH PF00780.22 PVD39162.1 - 0.024 14.3 0.7 2.8 7.5 0.1 2.2 1 1 1 2 2 2 0 CNH domain CPSF_A PF03178.15 PVD39162.1 - 0.042 13.2 0.2 0.4 9.9 0.1 2.3 1 1 1 2 2 2 0 CPSF A subunit region Ge1_WD40 PF16529.5 PVD39162.1 - 0.053 12.5 0.6 3.4 6.5 0.1 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Trypsin PF00089.26 PVD39163.1 - 2e-39 135.7 4.1 1.5e-21 77.3 0.5 2.2 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 PVD39163.1 - 0.011 16.7 0.3 0.22 12.4 0.0 2.4 1 1 1 2 2 2 0 Trypsin-like peptidase domain Trypsin PF00089.26 PVD39164.1 - 4.3e-68 229.4 0.1 6.6e-68 228.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD39164.1 - 2.8e-08 34.8 0.0 6.7e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD39164.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Macro PF01661.21 PVD39165.1 - 3e-28 98.2 1.5 3.6e-28 98.0 0.1 1.8 2 0 0 2 2 2 1 Macro domain Histone PF00125.24 PVD39165.1 - 1.2e-15 58.1 0.9 2e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PVD39165.1 - 8.6e-07 28.6 0.0 3.8e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PVD39165.1 - 0.0019 18.4 0.3 0.017 15.4 0.0 2.7 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BLOC1_2 PF10046.9 PVD39166.1 - 4.2e-33 113.5 0.8 5.4e-33 113.2 0.8 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dna2 PF08696.11 PVD39166.1 - 0.079 12.8 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF1759 PF03564.15 PVD39166.1 - 0.092 12.7 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Transposase_24 PF03004.14 PVD39166.1 - 0.12 12.5 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF948 PF06103.11 PVD39166.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-RING_2 PF13639.6 PVD39167.1 - 1.9e-13 50.5 10.9 2.7e-13 50.0 10.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PVD39167.1 - 5.2e-11 42.1 3.6 5.2e-11 42.1 3.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PVD39167.1 - 3.6e-09 36.3 11.6 5.5e-09 35.7 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PVD39167.1 - 2.5e-08 33.6 11.1 3.8e-08 33.1 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD39167.1 - 1.6e-07 31.5 10.9 3.6e-07 30.4 10.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD39167.1 - 1.1e-06 28.6 7.0 1.9e-06 27.8 4.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 PVD39167.1 - 7.8e-06 25.6 3.6 0.012 15.5 0.1 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 PVD39167.1 - 1e-05 25.5 3.8 1.6e-05 24.9 3.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PVD39167.1 - 1.2e-05 25.1 7.5 1.8e-05 24.5 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD39167.1 - 1.6e-05 24.7 10.2 2.6e-05 24.1 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PVD39167.1 - 0.00076 19.3 10.9 0.033 14.1 11.4 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PVD39167.1 - 0.0025 17.6 4.6 0.0043 16.8 4.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 PVD39167.1 - 0.0032 17.2 7.9 0.0056 16.4 7.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 PVD39167.1 - 0.0085 16.2 7.4 0.07 13.3 7.4 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 PVD39167.1 - 0.018 15.0 6.1 0.098 12.6 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2225 PF09986.9 PVD39167.1 - 0.019 14.7 1.0 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-WRNIP1_ubi PF18279.1 PVD39167.1 - 1.6 9.6 6.4 22 6.0 1.1 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C3HC4_4 PF15227.6 PVD39167.1 - 6.2 7.1 12.2 41 4.5 12.4 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RRM_1 PF00076.22 PVD39168.1 - 2.5e-32 110.5 0.6 1.7e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD39168.1 - 1.9e-13 50.3 0.3 2e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PVD39168.1 - 2.5e-05 24.2 0.1 0.037 14.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PVD39168.1 - 0.00036 20.5 0.2 0.15 12.1 0.1 2.5 2 1 0 2 2 2 2 RNA binding motif EF-hand_6 PF13405.6 PVD39169.1 - 1.4e-16 59.0 12.1 0.05 13.6 0.1 9.7 10 0 0 10 10 10 5 EF-hand domain EF-hand_7 PF13499.6 PVD39169.1 - 2.9e-14 53.3 14.3 0.1 13.0 0.1 8.4 8 1 0 8 8 8 5 EF-hand domain pair EF-hand_1 PF00036.32 PVD39169.1 - 3e-14 51.4 1.6 1 9.1 0.1 9.3 9 0 0 9 9 9 5 EF hand EF-hand_8 PF13833.6 PVD39169.1 - 2.9e-10 39.8 1.4 0.098 12.5 0.0 6.9 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_11 PF08976.11 PVD39169.1 - 0.00015 22.6 11.6 0.099 13.5 0.0 5.2 6 0 0 6 6 6 2 EF-hand domain RST PF12174.8 PVD39169.1 - 0.0041 17.0 8.9 7.6 6.5 0.5 7.3 7 0 0 7 7 7 1 RCD1-SRO-TAF4 (RST) plant domain DUF1870 PF08965.10 PVD39169.1 - 0.13 12.3 0.5 22 5.1 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1870) HBS1_N PF08938.10 PVD39169.1 - 0.14 12.5 0.1 0.7 10.2 0.1 2.3 1 0 0 1 1 1 0 HBS1 N-terminus DUF3715 PF12509.8 PVD39170.1 - 5.6e-24 84.8 0.1 5.6e-24 84.8 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3715) SoxG PF04268.12 PVD39170.1 - 0.12 12.5 0.0 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family HTH_49 PF18010.1 PVD39170.1 - 0.55 10.2 3.2 17 5.4 1.6 2.9 3 0 0 3 3 3 0 Cry35Ab1 HTH C-terminal domain CBM_6 PF03422.15 PVD39172.1 - 0.026 14.8 0.0 0.039 14.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) CBM-like PF14683.6 PVD39173.1 - 0.057 13.3 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III EGF_alliinase PF04863.13 PVD39176.1 - 0.23 11.9 0.4 0.23 11.9 0.4 1.9 2 0 0 2 2 2 0 Alliinase EGF-like domain PAX PF00292.18 PVD39177.1 - 2.6e-72 240.6 0.7 4.8e-72 239.7 0.7 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 PVD39177.1 - 1.1e-05 25.0 0.0 8.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 PVD39177.1 - 0.00033 21.2 0.0 0.44 11.2 0.0 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 PVD39177.1 - 0.016 15.3 0.2 0.056 13.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 PVD39177.1 - 0.075 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 InsA C-terminal domain Ribosomal_S13_N PF08069.12 PVD39177.1 - 0.11 12.5 0.9 0.6 10.2 0.0 2.6 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain HTH_38 PF13936.6 PVD39177.1 - 0.91 9.3 2.8 0.8 9.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain UDPGT PF00201.18 PVD39186.1 - 6.9e-59 199.9 0.0 8.3e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PVD39186.1 - 0.0043 17.1 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3169 PF11368.8 PVD39186.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) UDPGT PF00201.18 PVD39187.1 - 0.034 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_5 PF08323.11 PVD39187.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 PVD39187.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like Polysacc_deac_2 PF04748.13 PVD39187.1 - 0.25 10.5 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Telomere_reg-2 PF10193.9 PVD39188.1 - 1.8e-17 63.7 2.1 6.4e-17 62.0 0.3 2.9 2 1 0 2 2 2 1 Telomere length regulation protein Aconitase PF00330.20 PVD39189.1 - 1.7e-149 498.7 0.0 2.2e-149 498.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PVD39189.1 - 4.4e-45 153.2 0.0 8.4e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro_20 PF00728.22 PVD39190.1 - 2.2e-05 24.0 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 PVD39190.1 - 0.0012 18.3 0.0 0.0073 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4838) Myosin_head PF00063.21 PVD39191.1 - 6e-159 530.4 9.0 5.4e-94 315.7 4.2 3.3 1 1 2 3 3 3 3 Myosin head (motor domain) MyTH4 PF00784.17 PVD39191.1 - 2.1e-52 176.2 12.1 3.7e-28 98.1 0.1 3.8 3 0 0 3 3 2 2 MyTH4 domain FERM_M PF00373.18 PVD39191.1 - 8.6e-11 42.3 0.6 1.3e-09 38.5 0.0 3.4 3 0 0 3 3 3 1 FERM central domain SH3_9 PF14604.6 PVD39191.1 - 2.4e-09 36.9 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PVD39191.1 - 9.3e-09 34.8 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 PVD39191.1 - 2.7e-07 29.8 21.6 0.0028 17.3 1.0 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif SH3_1 PF00018.28 PVD39191.1 - 0.0004 19.9 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain AAA_22 PF13401.6 PVD39191.1 - 0.049 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PVD39191.1 - 0.26 11.7 5.2 1.1 9.6 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 PVD39191.1 - 0.26 11.8 1.1 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Antimicrobial_9 PF08104.11 PVD39191.1 - 0.43 10.6 1.5 28 4.8 0.3 2.5 2 0 0 2 2 2 0 Ponericin L family Glycos_transf_1 PF00534.20 PVD39192.1 - 2e-11 43.7 0.0 2.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PVD39192.1 - 2.8e-11 44.0 0.0 4.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PVD39192.1 - 4.4e-05 23.8 0.0 7.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PVD39192.1 - 0.0059 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PVD39192.1 - 0.098 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Patched PF02460.18 PVD39194.1 - 0.0014 16.8 9.0 0.067 11.3 1.7 2.2 1 1 1 2 2 2 2 Patched family DUF4756 PF15948.5 PVD39194.1 - 7.8 6.3 21.0 9.6 6.0 1.7 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4756) VWA_2 PF13519.6 PVD39197.1 - 7.7e-08 33.0 0.0 1e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CLCA PF08434.11 PVD39197.1 - 1e-07 31.6 0.1 1.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 PVD39197.1 - 1e-06 29.1 0.0 1.4e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CLCA PF08434.11 PVD39198.1 - 1.4e-30 106.6 0.0 1.2e-29 103.5 0.0 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal TMEM51 PF15345.6 PVD39199.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 YtkA PF13115.6 PVD39199.1 - 0.075 13.6 0.0 0.23 12.1 0.0 1.8 1 0 0 1 1 1 0 YtkA-like CLCA PF08434.11 PVD39200.1 - 4.5e-31 108.2 0.2 7.6e-20 71.3 0.0 2.8 1 1 1 2 2 2 2 Calcium-activated chloride channel N terminal HH_signal PF01085.18 PVD39201.1 - 8.4e-13 48.3 0.0 3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Hedgehog amino-terminal signalling domain GTP_EFTU PF00009.27 PVD39202.1 - 1.8e-43 148.3 0.0 2.9e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PVD39202.1 - 1.7e-24 86.2 1.4 3.9e-24 85.1 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PVD39202.1 - 3.1e-10 40.3 0.2 9.4e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PAM2 PF07145.15 PVD39202.1 - 0.002 17.7 0.0 0.002 17.7 0.0 2.9 3 0 0 3 3 3 1 Ataxin-2 C-terminal region MMR_HSR1 PF01926.23 PVD39202.1 - 0.002 18.2 0.0 0.0091 16.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 PVD39202.1 - 0.092 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 LUC7 PF03194.15 PVD39203.1 - 6.1e-84 281.6 30.9 6.1e-84 281.6 30.9 2.8 1 1 2 3 3 3 1 LUC7 N_terminus ApbA_C PF08546.11 PVD39203.1 - 0.086 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Methyltransf_16 PF10294.9 PVD39204.1 - 1.8e-17 63.6 0.0 2.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 PVD39204.1 - 0.065 13.9 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Amino_oxidase PF01593.24 PVD39205.1 - 4.9e-69 233.8 0.0 1e-50 173.4 0.0 2.9 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase SIR2 PF02146.17 PVD39205.1 - 5.1e-25 88.4 0.1 1.7e-18 67.2 0.0 2.5 1 1 1 2 2 2 2 Sir2 family NAD_binding_8 PF13450.6 PVD39205.1 - 2.3e-12 46.9 0.1 4.9e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PVD39205.1 - 2.2e-07 30.8 1.3 4.9e-07 29.6 1.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PVD39205.1 - 9.7e-05 21.6 2.9 0.00018 20.7 2.9 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PVD39205.1 - 0.00033 20.0 3.7 0.0028 16.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 PVD39205.1 - 0.00094 18.9 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FAD_binding_3 PF01494.19 PVD39205.1 - 0.0014 17.9 1.5 0.0034 16.7 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 PVD39205.1 - 0.0024 17.2 0.4 0.0045 16.3 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PVD39205.1 - 0.0027 17.0 0.8 0.0027 17.0 0.8 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 PVD39205.1 - 0.0028 16.5 0.0 0.0057 15.5 0.0 1.5 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 PVD39205.1 - 0.0041 16.2 0.8 0.06 12.4 0.4 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 PVD39205.1 - 0.0044 17.0 0.8 0.2 11.7 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 PVD39205.1 - 0.032 12.9 2.7 0.038 12.7 0.7 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 PVD39205.1 - 0.046 13.1 2.0 0.16 11.3 1.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-C4pol PF14260.6 PVD39205.1 - 0.074 13.5 4.6 0.11 12.9 0.2 3.2 3 0 0 3 3 2 0 C4-type zinc-finger of DNA polymerase delta Shikimate_DH PF01488.20 PVD39205.1 - 0.13 12.4 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 PVD39205.1 - 0.26 10.3 3.7 0.083 12.0 0.9 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 PVD39205.1 - 1.9 9.1 6.2 0.86 10.2 1.5 2.9 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 PVD39206.1 - 8.4e-31 106.7 0.0 3.6e-15 56.4 0.0 2.3 2 1 0 2 2 2 2 Rhodanese-like domain Tuberin PF03542.16 PVD39207.1 - 4.2e-121 404.3 4.6 8.7e-121 403.3 4.6 1.6 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.8 PVD39207.1 - 3.4e-78 263.7 1.2 7.1e-78 262.6 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 PVD39207.1 - 1.3e-38 132.4 0.0 2.5e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP zf-C3HC4_2 PF13923.6 PVD39208.1 - 2.3e-08 33.7 16.4 7.4e-08 32.1 16.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD39208.1 - 1.1e-07 32.1 17.7 4.4e-07 30.1 17.7 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PVD39208.1 - 7.3e-06 25.8 13.9 2.3e-05 24.1 13.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 PVD39208.1 - 7.1e-05 23.4 6.7 7.1e-05 23.4 6.7 3.4 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 PVD39208.1 - 0.00011 22.0 17.7 0.00011 22.0 17.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PVD39208.1 - 0.00016 21.9 11.9 0.00016 21.9 11.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PVD39208.1 - 0.0003 20.8 12.6 0.0003 20.8 12.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Sina PF03145.16 PVD39208.1 - 0.00037 20.5 13.3 0.0018 18.2 1.6 2.7 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_4 PF15227.6 PVD39208.1 - 0.0076 16.4 10.4 0.057 13.6 10.3 2.6 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PVD39208.1 - 0.013 15.3 14.3 0.037 13.9 14.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PVD39208.1 - 0.68 10.0 7.9 2.3 8.3 7.9 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Xylo_C PF12529.8 PVD39209.1 - 2e-53 180.7 0.0 3.3e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 PVD39209.1 - 1.7e-45 155.4 0.9 5e-45 153.9 0.3 1.9 2 0 0 2 2 2 1 Core-2/I-Branching enzyme WSC PF01822.19 PVD39209.1 - 3.7e-18 65.5 9.9 3.7e-18 65.5 9.9 1.9 2 0 0 2 2 2 1 WSC domain NPL4 PF05021.15 PVD39210.1 - 7.3e-119 396.7 0.0 8.7e-119 396.4 0.0 1.0 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 PVD39210.1 - 7.7e-21 74.8 2.1 2e-13 50.7 0.3 2.5 1 1 1 2 2 2 2 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 PVD39210.1 - 0.00059 19.1 0.6 0.0016 17.8 0.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1397 PF07165.11 PVD39211.1 - 1.2e-05 24.9 10.2 0.00026 20.5 4.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1397) CPG4 PF15481.6 PVD39211.1 - 2.5 8.8 16.4 3.7 8.3 1.0 3.6 2 1 1 3 3 3 0 Chondroitin proteoglycan 4 Phage_GPL PF05926.11 PVD39212.1 - 5.6e-05 23.2 0.1 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Phage head completion protein (GPL) DUF4400 PF14348.6 PVD39212.1 - 0.042 13.3 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) TPR_7 PF13176.6 PVD39212.1 - 0.12 12.4 0.2 22 5.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat VAD1-2 PF15310.6 PVD39212.1 - 0.37 10.6 3.1 7.8 6.3 0.4 2.3 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling AMP-binding PF00501.28 PVD39213.1 - 1.2e-28 99.9 0.0 5.7e-26 91.1 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39213.1 - 3.4e-08 34.3 0.0 6.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD39214.1 - 3.4e-20 72.0 0.0 4.2e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39214.1 - 3.3e-07 31.2 0.0 5.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD39215.1 - 4.5e-69 233.1 0.0 7.7e-22 77.5 0.1 4.1 3 1 1 4 4 4 4 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39215.1 - 1.6e-17 64.2 0.2 5.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD39216.1 - 9.5e-51 172.7 0.0 1.1e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39216.1 - 5.4e-08 33.7 0.0 1e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 PVD39217.1 - 3.4e-51 174.2 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39217.1 - 4.9e-08 33.8 0.0 9.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain C1q PF00386.21 PVD39218.1 - 1.3e-21 77.1 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 C1q domain bZIP_1 PF00170.21 PVD39218.1 - 0.088 12.9 0.1 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 PVD39218.1 - 0.26 11.7 1.0 0.35 11.3 0.1 1.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Thioredoxin PF00085.20 PVD39219.1 - 1.9e-16 59.9 0.0 4.3e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 PVD39219.1 - 0.00029 20.9 0.0 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PVD39219.1 - 0.04 14.4 0.0 1.4 9.4 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin-like domain Lig_chan PF00060.26 PVD39222.1 - 2.1e-20 73.1 0.0 4.5e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD39222.1 - 5.4e-11 42.3 0.0 5.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 PVD39222.1 - 0.00014 22.0 0.0 0.0064 16.7 0.0 2.5 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site GUN4_N PF16416.5 PVD39222.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal Lig_chan PF00060.26 PVD39225.1 - 2e-30 105.6 0.1 3.5e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 PVD39225.1 - 1.6e-24 86.3 0.1 4.4e-18 65.6 0.1 2.8 1 1 1 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 PVD39225.1 - 1.1e-16 60.9 0.0 1.1e-09 38.0 0.0 3.1 3 0 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 PVD39225.1 - 2e-13 50.2 0.1 2.4e-12 46.6 0.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 PVD39226.1 - 2.2e-28 99.0 0.4 3.6e-28 98.3 0.4 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PVD39226.1 - 6.4e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 PVD39226.1 - 2.3e-22 79.3 0.0 4.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site A_amylase_inhib PF01356.19 PVD39226.1 - 0.026 14.5 0.3 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Alpha amylase inhibitor GPS PF01825.21 PVD39226.1 - 0.14 12.7 2.2 0.19 12.3 0.4 2.1 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif ANF_receptor PF01094.28 PVD39227.1 - 6.4e-21 74.8 0.2 9.2e-21 74.3 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region HAUS2 PF15003.6 PVD39228.1 - 1.5e-30 106.3 2.9 2.1e-30 105.9 2.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Tetraspanin PF00335.20 PVD39228.1 - 1.4e-16 60.9 3.2 2.4e-16 60.2 3.2 1.3 1 0 0 1 1 1 1 Tetraspanin family C1q PF00386.21 PVD39228.1 - 6e-11 42.6 0.1 1.6e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD39228.1 - 0.00073 19.4 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 BclA C-terminal domain TMF_TATA_bd PF12325.8 PVD39228.1 - 0.083 13.1 3.6 0.12 12.5 1.7 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NikR_C PF08753.11 PVD39228.1 - 0.091 12.9 1.4 3.6 7.8 0.2 3.0 3 0 0 3 3 3 0 NikR C terminal nickel binding domain SdpI PF13630.6 PVD39228.1 - 0.94 9.7 2.6 1.9 8.7 2.6 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family C1q PF00386.21 PVD39229.1 - 5.9e-16 58.8 0.2 8.8e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 PVD39229.1 - 0.00014 21.8 0.2 0.00026 20.9 0.2 1.4 1 1 0 1 1 1 1 BclA C-terminal domain TRAF_BIRC3_bd PF16673.5 PVD39229.1 - 0.00043 20.0 0.2 0.0007 19.3 0.2 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 PVD39229.1 - 0.01 14.7 0.3 0.015 14.2 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 PVD39229.1 - 0.012 15.4 0.5 0.017 15.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc29 PF17082.5 PVD39229.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4795 PF16043.5 PVD39229.1 - 0.032 13.8 0.3 0.046 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 PVD39229.1 - 0.053 13.6 0.6 0.078 13.1 0.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 PVD39229.1 - 0.081 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Fibroin_P25 PF07294.11 PVD39229.1 - 0.098 12.7 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Fibroin P25 DBB PF14545.6 PVD39230.1 - 1.3e-10 41.3 0.1 3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIR_3 PF18567.1 PVD39230.1 - 0.0066 16.4 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 Toll/interleukin-1 receptor domain Drf_GBD PF06371.13 PVD39231.1 - 0.0052 16.4 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain EF-hand_7 PF13499.6 PVD39232.1 - 1.1e-13 51.4 3.3 1.7e-09 38.0 3.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PVD39232.1 - 3e-10 39.2 4.7 0.0036 17.1 1.4 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PVD39232.1 - 3.6e-10 38.7 4.4 0.00044 19.6 0.8 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PVD39232.1 - 2e-09 37.2 1.0 1.6e-06 27.9 0.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PVD39232.1 - 3e-06 26.4 2.7 1.1 8.9 0.0 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 PVD39232.1 - 0.0019 18.5 0.9 0.013 15.8 0.3 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Protocadherin PF08374.11 PVD39233.1 - 2.4e-05 24.4 0.1 4.4e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Protocadherin RIFIN PF02009.16 PVD39233.1 - 0.00038 20.5 0.1 0.00056 19.9 0.1 1.3 1 0 0 1 1 1 1 Rifin DUF2207 PF09972.9 PVD39233.1 - 0.0025 16.6 0.2 0.018 13.8 0.2 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Rax2 PF12768.7 PVD39233.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity NOD PF06816.13 PVD39233.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NOTCH protein DUF3377 PF11857.8 PVD39233.1 - 0.12 12.3 0.8 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 PVD39233.1 - 0.12 13.2 0.2 0.51 11.3 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LptF_LptG PF03739.14 PVD39233.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RCR PF12273.8 PVD39233.1 - 0.37 11.5 3.9 2.8 8.6 3.9 2.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CcmD PF04995.14 PVD39233.1 - 0.48 10.5 2.7 0.92 9.6 2.7 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Adeno_E3_CR2 PF02439.15 PVD39233.1 - 2.1 8.2 5.7 4.8 7.0 5.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 PVD39234.1 - 6.3e-29 100.3 8.2 1.8e-05 25.1 0.0 7.5 7 0 0 7 7 7 6 Cadherin domain MG1 PF17790.1 PVD39234.1 - 0.047 14.1 2.0 0.21 12.0 0.0 2.7 2 1 0 2 2 2 0 Macroglobulin domain MG1 Cadherin_4 PF17803.1 PVD39234.1 - 5.7 7.6 33.1 11 6.8 0.5 5.5 3 1 1 4 4 4 0 Bacterial cadherin-like domain Cadherin PF00028.17 PVD39235.1 - 1e-32 112.4 4.5 6.3e-20 71.4 0.2 4.9 3 1 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 PVD39235.1 - 0.0053 16.6 0.2 0.028 14.3 0.1 2.2 2 0 0 2 2 2 1 Cadherin-like FAM104 PF15434.6 PVD39235.1 - 0.038 14.5 0.3 0.1 13.2 0.3 1.7 1 0 0 1 1 1 0 Family 104 DapH_N PF08503.10 PVD39235.1 - 0.059 13.6 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Cadherin PF00028.17 PVD39236.1 - 2.5e-33 114.4 0.9 2e-14 53.8 0.0 3.7 3 1 0 3 3 3 3 Cadherin domain Cadherin_3 PF16184.5 PVD39236.1 - 0.00016 21.6 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Cadherin-like RET_CLD1 PF17756.1 PVD39236.1 - 0.00098 19.4 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 RET Cadherin like domain 1 Cadherin_2 PF08266.12 PVD39236.1 - 0.0019 18.0 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Cadherin-like Cadherin_pro PF08758.11 PVD39236.1 - 0.026 14.7 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Cadherin prodomain like Cadherin PF00028.17 PVD39237.1 - 5.5e-66 219.1 12.9 5.6e-20 71.6 0.0 6.5 5 1 1 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 PVD39237.1 - 1.5e-08 34.6 13.7 0.0083 16.1 0.0 7.3 7 2 1 8 8 8 4 Cadherin-like Cadherin_2 PF08266.12 PVD39237.1 - 0.00022 21.0 0.0 0.35 10.7 0.0 4.5 5 1 0 5 5 5 1 Cadherin-like RSD-2 PF07547.13 PVD39237.1 - 0.038 14.5 0.8 2.9 8.4 0.2 3.5 3 0 0 3 3 3 0 RSD-2 N-terminal domain RET_CLD1 PF17756.1 PVD39237.1 - 0.11 12.7 0.0 8.4 6.7 0.0 3.7 4 1 0 4 4 4 0 RET Cadherin like domain 1 Cadherin PF00028.17 PVD39238.1 - 3.2e-22 78.8 7.8 2.8e-12 46.9 0.3 5.2 5 1 0 5 5 5 4 Cadherin domain Cadherin PF00028.17 PVD39239.1 - 1.6e-131 429.1 32.8 2.3e-19 69.6 0.1 14.5 14 0 0 14 14 14 14 Cadherin domain Cadherin_3 PF16184.5 PVD39239.1 - 2.1e-10 40.6 8.8 0.73 9.9 0.0 9.1 9 0 0 9 9 9 3 Cadherin-like Cadherin_2 PF08266.12 PVD39239.1 - 1e-08 34.9 0.0 0.47 10.3 0.0 7.3 8 0 0 8 8 8 1 Cadherin-like Cadherin_pro PF08758.11 PVD39239.1 - 0.00082 19.5 0.2 5.1 7.3 0.0 5.7 7 0 0 7 7 7 1 Cadherin prodomain like Y_Y_Y PF07495.13 PVD39239.1 - 0.0063 16.4 3.8 1.6 8.7 0.2 5.6 5 0 0 5 5 5 1 Y_Y_Y domain Big_3_2 PF12245.8 PVD39239.1 - 0.11 12.8 1.7 16 5.8 0.1 3.7 3 0 0 3 3 3 0 Bacterial Ig-like domain TMEM52 PF14979.6 PVD39239.1 - 1 9.2 6.6 0.23 11.4 0.8 2.9 3 0 0 3 3 3 0 Transmembrane 52 Cadherin PF00028.17 PVD39240.1 - 4.5e-151 491.8 52.1 7.5e-20 71.2 0.7 14.6 14 0 0 14 14 14 14 Cadherin domain Cadherin_3 PF16184.5 PVD39240.1 - 6.6e-13 48.6 30.2 0.25 11.4 0.1 12.1 12 0 0 12 12 12 5 Cadherin-like Cadherin_2 PF08266.12 PVD39240.1 - 2e-09 37.2 0.1 0.0079 16.0 0.0 6.5 7 0 0 7 7 7 1 Cadherin-like RET_CLD1 PF17756.1 PVD39240.1 - 0.00033 20.9 0.0 26 5.1 0.0 5.9 6 0 0 6 6 6 0 RET Cadherin like domain 1 TMEM154 PF15102.6 PVD39240.1 - 0.01 15.7 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 PVD39240.1 - 0.045 14.0 0.3 0.13 12.5 0.3 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PepSY PF03413.19 PVD39240.1 - 0.057 14.0 2.0 8.2 7.1 0.1 4.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain SIT PF15330.6 PVD39240.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 PVD39240.1 - 0.14 13.1 0.5 0.33 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RCR PF12273.8 PVD39240.1 - 0.86 10.3 5.6 0.72 10.5 0.1 3.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red LPMO_10 PF03067.15 PVD39241.1 - 1.2e-22 81.5 0.3 1.7e-10 41.9 0.0 2.1 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading C2 PF00168.30 PVD39243.1 - 3e-24 85.3 0.2 4.6e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 PVD39243.1 - 4.2e-05 23.2 0.3 0.13 11.8 0.0 2.3 2 1 0 2 2 2 2 CEP76 C2 domain bZIP_1 PF00170.21 PVD39247.1 - 1.6e-10 40.9 21.3 1.6e-10 40.9 21.3 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PVD39247.1 - 2e-09 37.4 22.6 2.3e-09 37.2 19.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD39247.1 - 0.00012 22.5 18.7 0.00012 22.5 18.7 2.3 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF4094 PF13334.6 PVD39247.1 - 0.41 11.1 5.9 2.8 8.4 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2347 PF09804.9 PVD39247.1 - 0.5 9.9 3.0 0.65 9.5 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Presenilin PF01080.17 PVD39247.1 - 0.6 8.8 3.3 0.63 8.7 3.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 PVD39247.1 - 0.76 9.1 6.5 0.87 8.9 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 PVD39247.1 - 1 9.2 11.3 1.8 8.4 11.3 1.4 1 0 0 1 1 1 0 Coilin N-terminus Tho2 PF11262.8 PVD39247.1 - 1.4 8.1 9.4 2.1 7.5 9.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Phlebovirus_NSM PF07246.11 PVD39247.1 - 2.7 7.3 10.7 4 6.8 10.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_11 PF13086.6 PVD39247.1 - 2.8 7.7 13.0 4.8 6.9 13.0 1.3 1 0 0 1 1 1 0 AAA domain GvpL_GvpF PF06386.11 PVD39247.1 - 3.7 7.4 10.4 5.4 6.9 10.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TSP_1 PF00090.19 PVD39248.1 - 6.3e-61 202.4 97.9 2.9e-13 49.8 7.9 8.4 8 0 0 8 8 8 7 Thrombospondin type 1 domain Laminin_G_2 PF02210.24 PVD39248.1 - 1e-20 74.6 0.1 8e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 PVD39248.1 - 9e-14 51.8 0.0 5e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 PVD39248.1 - 5.6e-07 29.8 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Band_7 PF01145.25 PVD39249.1 - 7.9e-18 65.1 5.3 6.1e-17 62.2 5.3 2.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family V-ATPase_G_2 PF16999.5 PVD39249.1 - 0.046 14.1 16.4 0.19 12.1 7.7 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ALMT PF11744.8 PVD39249.1 - 0.11 11.3 2.6 0.15 10.8 2.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2120 PF09893.9 PVD39249.1 - 0.36 10.9 2.6 2.1 8.4 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DivIVA PF05103.13 PVD39249.1 - 0.54 10.3 10.6 1.7 8.7 10.5 1.8 1 1 0 1 1 1 0 DivIVA protein Flot PF15975.5 PVD39249.1 - 4.2 7.6 10.3 46 4.2 8.1 2.4 1 1 1 2 2 2 0 Flotillin Arf PF00025.21 PVD39250.1 - 2.8e-50 170.2 0.0 3.2e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PVD39250.1 - 2.4e-16 59.7 0.0 2.8e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD39250.1 - 6.3e-16 58.7 0.0 8.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PVD39250.1 - 3.6e-12 46.1 0.0 4.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PVD39250.1 - 2.1e-08 33.7 0.4 2.9e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PVD39250.1 - 1.3e-06 28.4 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PVD39250.1 - 0.0001 21.9 0.0 0.0025 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PVD39250.1 - 0.00033 20.1 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PVD39250.1 - 0.00096 18.7 0.7 0.0099 15.4 0.7 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B ALMS_repeat PF18727.1 PVD39250.1 - 0.044 13.7 0.2 0.075 12.9 0.2 1.3 1 0 0 1 1 1 0 Alstrom syndrome repeat AAA_14 PF13173.6 PVD39250.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 PVD39250.1 - 0.12 11.9 0.1 9.8 5.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 7tm_1 PF00001.21 PVD39251.1 - 8.6e-31 107.2 1.2 1e-30 107.0 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2852 PF11014.8 PVD39251.1 - 1 9.6 4.3 20 5.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) 7tm_1 PF00001.21 PVD39252.1 - 8.2e-31 107.3 12.7 1e-30 106.9 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD39252.1 - 0.027 14.1 7.7 0.045 13.4 7.6 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx GWT1 PF06423.12 PVD39252.1 - 1.1 9.4 6.1 7.2 6.7 0.3 2.7 1 1 1 2 2 2 0 GWT1 7tm_4 PF13853.6 PVD39252.1 - 3.1 7.4 11.8 3 7.5 7.2 2.5 2 1 0 2 2 2 0 Olfactory receptor Methyltransf_16 PF10294.9 PVD39253.1 - 7.4e-12 45.3 0.1 4.8e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 PVD39253.1 - 0.00052 19.5 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PVD39253.1 - 0.0011 18.6 0.0 0.0028 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PVD39253.1 - 0.0015 19.2 0.0 0.028 15.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain DOT1 PF08123.13 PVD39253.1 - 0.0062 16.1 0.1 0.12 11.8 0.0 2.5 2 1 0 2 2 2 1 Histone methylation protein DOT1 DUF4749 PF15936.5 PVD39254.1 - 3.2e-13 50.6 1.8 3.4e-13 50.5 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) LIM PF00412.22 PVD39254.1 - 2.9e-12 46.6 1.5 5e-12 45.9 1.5 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 PVD39254.1 - 9.3e-09 35.0 0.2 3.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PVD39254.1 - 8.8e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD39254.1 - 0.0058 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain zinc_ribbon_12 PF11331.8 PVD39254.1 - 2.8 7.8 6.6 0.5 10.2 0.2 2.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain VEFS-Box PF09733.9 PVD39255.1 - 1.8e-50 170.3 1.4 2.9e-50 169.6 1.4 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein LIM PF00412.22 PVD39255.1 - 1.7e-31 108.2 17.8 6e-13 48.8 4.4 3.7 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 PVD39255.1 - 4e-11 43.1 0.0 7.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD39255.1 - 7.2e-09 35.4 0.1 1.7e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD39255.1 - 0.001 19.3 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 PVD39256.1 - 6.8e-35 120.6 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PVD39256.1 - 1.8e-34 119.3 0.0 3e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 PVD39256.1 - 2e-16 59.2 0.5 5.2e-16 57.8 0.5 1.8 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 PVD39256.1 - 7.8e-05 23.7 0.6 0.00015 22.8 0.6 1.5 1 0 0 1 1 1 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 PVD39256.1 - 0.00014 20.8 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PVD39256.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_CR2 PF02439.15 PVD39256.1 - 0.038 13.8 0.7 0.067 13.0 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1356 PF07092.12 PVD39256.1 - 0.039 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) APH PF01636.23 PVD39256.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PVD39256.1 - 0.047 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orf78 PF06024.12 PVD39256.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Trypsin PF00089.26 PVD39257.1 - 1.6e-53 181.8 0.0 5.5e-29 101.6 0.0 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 PVD39257.1 - 0.0001 23.2 0.0 0.0032 18.4 0.0 2.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 PVD39257.1 - 0.022 15.2 0.1 0.24 11.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1986) SSF PF00474.17 PVD39258.1 - 2e-33 115.8 25.7 3.3e-33 115.1 25.7 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Alpha_GJ PF03229.13 PVD39258.1 - 0.9 10.1 4.2 4 8.0 0.5 2.7 2 1 0 2 2 2 0 Alphavirus glycoprotein J SSF PF00474.17 PVD39261.1 - 1e-12 47.6 5.1 1.5e-12 47.1 5.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 PVD39262.1 - 8.2e-14 51.3 12.2 1.2e-13 50.7 12.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3060 PF11259.8 PVD39262.1 - 0.035 13.8 0.0 4.4 7.1 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3060) Glyco_transf_22 PF03901.17 PVD39263.1 - 6.2e-43 147.6 27.6 7.8e-43 147.3 27.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Metallophos PF00149.28 PVD39264.1 - 2.5e-10 41.2 1.2 3.4e-10 40.7 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAM181 PF15238.6 PVD39265.1 - 7.1e-05 22.8 0.6 7.1e-05 22.8 0.6 1.9 2 0 0 2 2 2 1 FAM181 SUIM_assoc PF16619.5 PVD39265.1 - 1.1 9.4 7.8 0.66 10.1 2.3 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 PVD39265.1 - 4.8 8.1 14.7 0.11 13.4 4.5 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 CCDC154 PF15450.6 PVD39267.1 - 1.5e-14 53.5 23.6 2.1e-14 53.0 23.6 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 Herpes_MCP PF03122.14 PVD39267.1 - 0.0099 13.4 1.1 0.01 13.3 1.1 1.1 1 0 0 1 1 1 1 Herpes virus major capsid protein Vac_Fusion PF02346.16 PVD39267.1 - 0.027 14.1 1.0 1.2 8.8 0.1 3.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Spc7 PF08317.11 PVD39267.1 - 0.031 13.2 27.4 0.0095 14.9 14.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Rab5-bind PF09311.11 PVD39267.1 - 0.11 11.8 24.5 0.75 9.1 2.1 2.4 1 1 0 2 2 2 0 Rabaptin-like protein DUF5601 PF18151.1 PVD39267.1 - 0.3 11.4 3.1 0.63 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) DUF848 PF05852.11 PVD39267.1 - 1.7 8.8 21.7 0.58 10.3 3.0 3.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.12 PVD39267.1 - 1.9 8.5 21.9 5.2 7.1 0.8 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Helo_like_N PF17111.5 PVD39267.1 - 2 7.7 18.1 1.9 7.8 2.9 3.9 1 1 3 4 4 4 0 Fungal N-terminal domain of STAND proteins STAT_alpha PF01017.20 PVD39267.1 - 2.3 8.1 19.0 1.8 8.5 11.4 3.1 2 1 1 3 3 3 0 STAT protein, all-alpha domain DivIC PF04977.15 PVD39267.1 - 2.8 7.8 21.8 2.5 7.9 2.8 3.9 2 1 2 4 4 4 0 Septum formation initiator Cob_adeno_trans PF01923.18 PVD39267.1 - 3.7 7.7 13.6 0.4 10.8 3.4 2.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Phage_GPO PF05929.11 PVD39267.1 - 3.7 7.1 19.2 1.7 8.2 9.9 2.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 PVD39267.1 - 5.3 7.7 18.2 2.1 9.0 1.2 3.4 1 1 2 3 3 3 0 Initiation control protein YabA FUSC PF04632.12 PVD39267.1 - 5.8 5.3 7.3 5.2 5.5 1.5 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Flagellin_N PF00669.20 PVD39267.1 - 6.3 6.9 14.7 0.24 11.5 4.9 2.6 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region FmiP_Thoc5 PF09766.9 PVD39267.1 - 6.7 5.9 18.9 1.5 8.0 12.5 2.2 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 Fib_alpha PF08702.10 PVD39267.1 - 8.6 6.5 22.9 13 6.0 7.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 PVD39268.1 - 9.3e-18 64.3 19.1 5.1e-06 27.1 0.5 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PVD39268.1 - 6.5e-16 58.4 0.0 1.3e-14 54.2 0.0 2.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 PVD39268.1 - 3.3e-07 30.5 0.3 0.08 13.3 0.0 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD39268.1 - 7.9e-05 22.6 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CENP-B_dimeris PF09026.10 PVD39268.1 - 0.16 12.4 19.0 0.28 11.6 4.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.13 PVD39268.1 - 1 9.4 9.6 0.47 10.6 0.1 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling FAM176 PF14851.6 PVD39268.1 - 3.3 7.3 7.1 20 4.8 0.1 2.2 2 0 0 2 2 2 0 FAM176 family Fe_hyd_lg_C PF02906.14 PVD39269.1 - 1.7e-79 266.9 0.1 3e-79 266.1 0.1 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 PVD39269.1 - 2.5e-08 33.9 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 PVD39269.1 - 0.01 15.8 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 FAD synthetase Hyd_WA PF06462.12 PVD39270.1 - 1.2e-58 194.7 48.1 6e-12 45.3 0.3 8.4 8 0 0 8 8 8 7 Propeller Pex24p PF06398.11 PVD39270.1 - 2e-13 50.1 23.0 6.4e-08 32.0 5.7 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin WD40 PF00400.32 PVD39270.1 - 3.5e-13 49.8 0.0 5.3e-05 23.9 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD39270.1 - 0.0018 18.5 0.2 6.6 7.1 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PVD39270.1 - 0.0042 17.0 0.1 0.042 13.7 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-CCHC PF00098.23 PVD39271.1 - 5.7e-13 48.3 35.8 0.00029 20.8 1.6 5.6 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 PVD39271.1 - 0.00032 20.6 36.7 0.0015 18.4 2.8 6.4 2 1 3 5 5 5 3 Zinc knuckle PKI PF02827.16 PVD39271.1 - 0.017 15.3 0.0 0.09 13.0 0.0 2.3 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor zf-CCHC_4 PF14392.6 PVD39271.1 - 2.3 8.0 32.3 0.36 10.6 1.4 5.3 4 1 1 5 5 5 0 Zinc knuckle Rhomboid PF01694.22 PVD39272.1 - 4.6e-32 111.1 11.4 4.6e-32 111.1 11.4 2.5 2 1 1 3 3 3 1 Rhomboid family DUF2070 PF09843.9 PVD39272.1 - 0.56 8.4 6.2 1.1 7.5 6.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_7 PF08395.12 PVD39272.1 - 0.6 9.2 14.1 5.7 6.0 0.1 2.9 3 0 0 3 3 3 0 7tm Chemosensory receptor Ac76 PF05814.11 PVD39272.1 - 3.9 7.6 4.8 4.9 7.2 2.7 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) QVR PF17064.5 PVD39276.1 - 0.00018 21.7 6.2 0.00028 21.1 6.2 1.3 1 0 0 1 1 1 1 Sleepless protein Zn_peptidase PF04228.13 PVD39278.1 - 0.01 15.3 0.3 0.011 15.3 0.3 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase bZIP_2 PF07716.15 PVD39279.1 - 1.4e-05 25.1 14.2 1.9e-05 24.6 14.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD39279.1 - 0.0019 18.3 13.2 0.0029 17.7 13.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD39279.1 - 0.038 14.5 8.9 0.053 14.0 8.9 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 PVD39279.1 - 0.061 11.9 5.5 0.075 11.6 5.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF2229 PF09989.9 PVD39279.1 - 0.064 12.9 0.4 0.072 12.7 0.4 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GCN5L1 PF06320.13 PVD39279.1 - 0.2 11.8 7.0 0.26 11.5 7.0 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) UPF0242 PF06785.11 PVD39279.1 - 0.43 10.7 9.1 0.52 10.4 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 PVD39279.1 - 2.2 8.8 11.0 2.8 8.4 11.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 PVD39280.1 - 8.6e-09 35.4 15.2 2e-08 34.2 15.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD39280.1 - 5.9e-07 29.5 19.0 1.5e-06 28.2 19.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PVD39280.1 - 2.8e-06 27.7 12.8 6.9e-06 26.5 12.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.9 PVD39280.1 - 0.56 10.4 13.0 1.1 9.5 13.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3395 PF11875.8 PVD39280.1 - 0.8 9.6 6.4 1.8 8.4 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Tho2 PF11262.8 PVD39280.1 - 0.98 8.6 8.6 1.5 7.9 8.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 PVD39280.1 - 2.9 8.0 10.2 5.7 7.0 10.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MAGE_N PF12440.8 PVD39280.1 - 5.4 7.8 8.7 0.4 11.4 0.7 3.0 3 1 0 3 3 3 0 Melanoma associated antigen family N terminal bZIP_2 PF07716.15 PVD39281.1 - 1.2e-06 28.5 14.9 1.2e-06 28.5 14.9 3.6 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD39281.1 - 6.2e-05 23.0 20.9 8.4e-05 22.6 18.0 2.7 1 1 1 2 2 2 1 bZIP transcription factor DUF3908 PF13048.6 PVD39281.1 - 0.47 10.7 4.1 0.64 10.3 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) DivIC PF04977.15 PVD39281.1 - 1.3 8.8 10.3 0.42 10.4 2.7 2.8 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 PVD39282.1 - 0.00028 20.9 8.3 0.00028 20.9 8.3 1.5 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PVD39282.1 - 0.00035 20.6 11.0 0.00053 20.0 11.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor MPS2 PF17060.5 PVD39282.1 - 0.0043 16.4 2.3 0.0051 16.1 2.3 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 BLOC1S3 PF15753.5 PVD39282.1 - 0.0056 16.8 1.5 0.0062 16.7 1.5 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 bZIP_Maf PF03131.17 PVD39282.1 - 0.0094 16.4 3.2 0.012 16.1 3.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Peptidase_U57 PF05582.12 PVD39282.1 - 0.037 13.3 2.1 0.045 13.0 2.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DsbC PF11412.8 PVD39282.1 - 0.055 13.5 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC SRF-TF PF00319.18 PVD39282.1 - 0.24 10.9 2.1 0.51 9.9 2.1 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) bZIP_1 PF00170.21 PVD39283.1 - 6.8e-10 38.9 19.3 6.8e-10 38.9 19.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PVD39283.1 - 6.8e-10 38.9 18.3 1.9e-09 37.4 18.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD39283.1 - 0.00011 22.7 20.1 0.00011 22.7 20.1 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF4407 PF14362.6 PVD39283.1 - 4.1 6.7 8.8 8.4 5.7 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 PVD39284.1 - 1.1e-06 28.6 18.4 2.5e-06 27.5 18.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD39284.1 - 0.00012 22.1 11.3 0.00012 22.1 11.3 2.7 2 1 1 3 3 3 1 Basic region leucine zipper HALZ PF02183.18 PVD39284.1 - 0.025 14.8 4.5 0.025 14.8 4.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF445 PF04286.12 PVD39284.1 - 0.067 13.0 4.7 0.04 13.7 3.3 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ADIP PF11559.8 PVD39284.1 - 0.2 11.7 18.1 0.39 10.8 18.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 PVD39284.1 - 0.55 10.4 20.2 1.1 9.4 20.2 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 PVD39284.1 - 0.77 8.8 17.6 3.1 6.8 18.2 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 PVD39284.1 - 0.88 8.4 2.5 1.2 7.9 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein bZIP_Maf PF03131.17 PVD39284.1 - 1.5 9.4 20.3 1.1 9.8 18.4 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF3450 PF11932.8 PVD39284.1 - 1.6 8.0 13.4 2.6 7.3 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 PVD39284.1 - 2 9.1 13.7 0.41 11.3 6.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 PVD39284.1 - 5.9 6.7 14.3 4.3 7.2 5.3 2.7 1 1 1 2 2 2 0 Septum formation initiator CAF-1_p150 PF11600.8 PVD39284.1 - 8.2 6.1 29.1 1.4 8.6 24.1 1.9 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal bZIP_1 PF00170.21 PVD39285.1 - 3.5e-07 30.2 7.9 5.5e-07 29.6 7.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PVD39285.1 - 9.3e-06 25.6 6.7 2.1e-05 24.5 6.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PVD39285.1 - 0.011 16.2 3.0 0.02 15.4 3.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor GP41 PF00517.17 PVD39285.1 - 0.016 15.2 0.8 0.047 13.6 0.8 1.8 1 1 0 1 1 1 0 Retroviral envelope protein Mcp5_PH PF12814.7 PVD39285.1 - 0.11 12.6 0.4 0.25 11.4 0.3 1.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology BTB PF00651.31 PVD39286.1 - 1.5e-12 47.7 0.8 6.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PVD39286.1 - 1.7e-09 37.7 0.1 1.1e-07 31.9 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch PAD_M PF08527.10 PVD39286.1 - 0.067 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Metallophos PF00149.28 PVD39287.1 - 3e-36 125.8 0.1 4.1e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL PF00657.22 PVD39290.1 - 4.4e-17 62.7 0.0 1.2e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 PVD39290.1 - 1.7e-16 61.1 0.0 1.2e-15 58.4 0.0 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family MIEAP PF16026.5 PVD39290.1 - 0.021 15.0 0.6 1.3 9.2 0.1 3.8 3 1 0 3 3 3 0 Mitochondria-eating protein CorA PF01544.18 PVD39290.1 - 0.57 9.5 2.8 3.4 6.9 0.4 2.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein eIF2A PF08662.11 PVD39291.1 - 1.1e-60 204.9 7.3 1.2e-55 188.4 1.9 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 PVD39291.1 - 5.7e-06 26.1 0.1 2.1e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltr_RsmF_N PF17125.5 PVD39291.1 - 0.011 16.2 0.1 2.2 8.8 0.0 3.3 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF HBM PF16591.5 PVD39291.1 - 0.035 13.5 0.9 0.059 12.8 0.9 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain DSBA PF01323.20 PVD39291.1 - 0.043 13.6 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain WD40 PF00400.32 PVD39291.1 - 0.095 13.6 5.1 36 5.5 0.7 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat FapA PF03961.13 PVD39291.1 - 0.76 8.3 3.5 1.2 7.6 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C3HC4_2 PF13923.6 PVD39292.1 - 7.2e-06 25.7 11.8 1.2e-05 25.1 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 PVD39292.1 - 7.7e-05 22.8 0.0 0.00025 21.1 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 PVD39292.1 - 0.00018 21.3 10.6 0.0003 20.6 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PVD39292.1 - 0.0049 17.2 11.7 0.008 16.5 11.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PVD39292.1 - 0.0057 16.6 11.7 0.0096 15.9 11.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PVD39292.1 - 0.032 14.4 11.1 0.057 13.6 11.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD39292.1 - 0.12 12.3 11.3 0.21 11.5 11.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PVD39292.1 - 1.3 9.0 5.2 2.5 8.0 5.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 PVD39292.1 - 1.6 8.8 10.0 3.9 7.6 10.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PVD39292.1 - 2.5 8.0 11.3 4.3 7.2 11.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PVD39292.1 - 2.9 7.8 10.2 5.3 7.0 10.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DWNN PF08783.11 PVD39293.1 - 3.3e-29 101.0 0.1 4.4e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 DWNN domain HAP1_N PF04849.13 PVD39294.1 - 1.3e-97 326.7 32.0 2.3e-97 326.0 32.0 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 PVD39294.1 - 1.1e-19 71.2 7.9 1.1e-19 71.2 7.9 2.7 2 1 1 3 3 3 1 Kinesin associated protein Microvir_H PF04687.12 PVD39294.1 - 0.11 11.9 1.0 0.23 10.8 1.0 1.5 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) FokI_C PF02980.16 PVD39294.1 - 0.32 11.0 0.1 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain bZIP_1 PF00170.21 PVD39294.1 - 0.54 10.4 26.0 0.43 10.7 4.5 3.9 3 1 0 3 3 3 0 bZIP transcription factor Fez1 PF06818.15 PVD39294.1 - 6.8 7.1 35.4 8.8 6.7 12.0 2.9 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 PVD39294.1 - 9 7.0 34.6 1.4 9.6 2.9 4.2 3 1 1 4 4 4 0 Initiation control protein YabA DHHC PF01529.20 PVD39295.1 - 5.3e-34 117.2 12.8 5.3e-34 117.2 12.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Transport_MerF PF11431.8 PVD39295.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.1 3 0 0 3 3 3 0 Membrane transport protein MerF FH2 PF02181.23 PVD39296.1 - 2.8e-90 303.2 5.3 3.9e-90 302.6 5.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ_6 PF17820.1 PVD39296.1 - 5e-15 55.1 0.3 3.8e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 PVD39296.1 - 1.9e-11 44.1 0.0 9.3e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PVD39296.1 - 5e-08 33.1 0.1 0.0001 22.6 0.0 3.4 3 0 0 3 3 3 2 PDZ domain DnaB_2 PF07261.11 PVD39296.1 - 0.16 11.7 0.1 15 5.4 0.0 3.1 3 0 0 3 3 3 0 Replication initiation and membrane attachment PRIMA1 PF16101.5 PVD39296.1 - 0.4 10.7 6.8 0.93 9.5 6.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VWA PF00092.28 PVD39299.1 - 6.9e-31 107.8 1.0 5.8e-25 88.5 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PVD39299.1 - 3.5e-08 34.0 1.1 2.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Hydrolase_like PF13242.6 PVD39299.1 - 0.068 13.2 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 HAD-hyrolase-like VWA PF00092.28 PVD39300.1 - 3.9e-81 271.5 9.5 2.8e-24 86.3 0.3 4.0 4 0 0 4 4 4 4 von Willebrand factor type A domain DUF3104 PF11302.8 PVD39300.1 - 0.00038 20.1 0.1 1.5 8.7 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3104) VWA_CoxE PF05762.14 PVD39300.1 - 0.015 14.7 0.8 8.2 5.7 0.0 3.7 4 0 0 4 4 4 0 VWA domain containing CoxE-like protein VWA PF00092.28 PVD39301.1 - 0 1700.7 64.9 7.6e-42 143.5 0.6 14.1 14 0 0 14 14 14 14 von Willebrand factor type A domain VWA_2 PF13519.6 PVD39301.1 - 2.1e-209 681.2 34.2 1.3e-15 57.9 0.1 14.4 14 0 0 14 14 14 14 von Willebrand factor type A domain VWA_3 PF13768.6 PVD39301.1 - 3.1e-96 319.5 0.0 3.8e-08 33.4 0.0 13.2 14 0 0 14 14 14 11 von Willebrand factor type A domain EGF PF00008.27 PVD39301.1 - 2.2e-30 104.6 56.6 1.3e-07 31.8 9.3 4.5 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 PVD39301.1 - 1.3e-16 60.5 45.2 6.7e-06 26.5 2.2 4.8 4 0 0 4 4 4 4 Human growth factor-like EGF EGF_2 PF07974.13 PVD39301.1 - 2.4e-06 27.8 70.3 0.057 13.8 13.1 4.5 4 0 0 4 4 4 4 EGF-like domain RuvX PF03652.15 PVD39301.1 - 3.9e-05 24.1 0.0 59 4.1 0.0 7.3 8 0 0 8 8 8 0 Holliday junction resolvase AhpC-TSA_2 PF13911.6 PVD39301.1 - 0.012 15.7 6.9 3.4e+02 1.4 0.0 9.1 11 0 0 11 11 11 0 AhpC/TSA antioxidant enzyme EGF_3 PF12947.7 PVD39301.1 - 0.35 11.1 45.0 0.12 12.6 3.8 4.6 4 0 0 4 4 4 0 EGF domain SOG2 PF10428.9 PVD39301.1 - 0.54 9.4 19.8 1.2 8.2 19.8 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein PRCC PF10253.9 PVD39301.1 - 0.92 10.3 4.7 2.8 8.7 4.7 1.8 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Hamartin PF04388.12 PVD39301.1 - 2.4 6.7 11.0 4.4 5.9 11.0 1.3 1 0 0 1 1 1 0 Hamartin protein EamA PF00892.20 PVD39302.1 - 1.6e-16 60.7 24.9 1e-09 38.7 11.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 PVD39302.1 - 3.9e-06 26.3 14.0 1.2e-05 24.7 11.7 2.5 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport DUF772 PF05598.11 PVD39302.1 - 0.11 12.5 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Transposase domain (DUF772) Pkinase PF00069.25 PVD39303.1 - 8.5e-69 231.9 0.0 1.1e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39303.1 - 4.1e-48 163.9 0.0 6.1e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD39303.1 - 7.5e-09 35.3 0.0 0.00029 20.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PB1 PF00564.24 PVD39303.1 - 2.1e-07 30.8 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 PVD39303.1 - 0.0032 16.3 0.0 0.0074 15.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PVD39303.1 - 0.13 12.2 0.2 1.7 8.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_8 PF13855.6 PVD39304.1 - 3.3e-35 119.6 28.2 2.6e-09 36.7 0.8 6.7 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PVD39304.1 - 7.7e-21 73.8 40.7 8e-06 26.1 1.0 8.0 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) Roc PF08477.13 PVD39304.1 - 4.5e-13 49.5 0.0 9.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 PVD39304.1 - 3.9e-11 43.1 0.0 1.2e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 PVD39304.1 - 4.2e-10 39.5 0.0 8.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Ras family LRR_9 PF14580.6 PVD39304.1 - 9.7e-07 28.5 15.8 0.0074 15.8 2.0 4.2 2 1 2 4 4 4 4 Leucine-rich repeat Death PF00531.22 PVD39304.1 - 1.2e-05 25.3 0.3 1.2e-05 25.3 0.3 2.9 4 0 0 4 4 4 1 Death domain Gtr1_RagA PF04670.12 PVD39304.1 - 0.00027 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PVD39304.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD39304.1 - 0.04 14.0 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_1 PF00560.33 PVD39304.1 - 5.4 8.0 45.3 8.2 7.4 0.3 12.1 11 3 1 12 12 12 0 Leucine Rich Repeat MIOX PF05153.15 PVD39305.1 - 3.5e-112 374.0 1.5 4e-112 373.8 1.5 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 PVD39305.1 - 0.00041 20.6 0.2 0.021 15.1 0.1 2.4 2 0 0 2 2 2 1 HD domain PAF PF15715.5 PVD39306.1 - 9.1e-19 68.4 5.5 1.7e-18 67.5 5.5 1.5 1 1 0 1 1 1 1 PCNA-associated factor histone like domain Bax1-I PF01027.20 PVD39307.1 - 1e-31 110.4 16.1 1.3e-31 110.1 16.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 PVD39307.1 - 0.0088 15.6 12.4 0.012 15.2 12.4 1.1 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF4328 PF14219.6 PVD39307.1 - 0.35 10.4 3.5 0.41 10.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DUF4418 PF14387.6 PVD39307.1 - 5.3 7.3 10.8 4.9 7.4 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) ELFV_dehydrog_N PF02812.18 PVD39308.1 - 2.5e-60 202.1 0.0 4.2e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 PVD39308.1 - 1.5e-49 168.9 0.0 1.2e-46 159.4 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L1 PF00687.21 PVD39309.1 - 3e-06 27.1 0.0 3.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Gar1 PF04410.14 PVD39309.1 - 0.017 14.9 0.6 0.03 14.1 0.6 1.6 1 1 0 1 1 1 0 Gar1/Naf1 RNA binding region Exo_endo_phos PF03372.23 PVD39310.1 - 2.9e-19 69.5 0.0 1.6e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 PVD39310.1 - 2.7e-09 36.7 11.3 4.1e-09 36.1 6.9 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PVD39310.1 - 7.5e-05 23.0 11.4 0.00014 22.1 2.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PVD39310.1 - 0.033 13.7 0.5 0.06 12.8 0.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeat NAD-GH PF10712.9 PVD39312.1 - 3.3e-18 65.5 0.1 4.4e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase GspH PF12019.8 PVD39312.1 - 0.11 13.0 3.1 0.39 11.2 3.1 2.0 1 1 0 1 1 1 0 Type II transport protein GspH NAD-GH PF10712.9 PVD39313.1 - 1.5e-18 66.6 0.2 2e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase GspH PF12019.8 PVD39313.1 - 0.1 13.0 2.9 0.35 11.3 2.9 2.0 1 1 0 1 1 1 0 Type II transport protein GspH Tetraspanin PF00335.20 PVD39316.1 - 9.7e-57 192.3 8.5 1.4e-56 191.8 8.5 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2754 PF10953.8 PVD39316.1 - 0.025 14.8 0.5 0.025 14.8 0.5 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2754) Cys_Knot_tox PF17486.2 PVD39316.1 - 0.04 14.1 1.7 0.11 12.8 1.7 1.8 1 0 0 1 1 1 0 Cystine knot toxins AAA_11 PF13086.6 PVD39317.1 - 1.9e-23 83.6 0.0 8.4e-13 48.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 PVD39317.1 - 6e-16 58.7 0.6 1.2e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PVD39317.1 - 3.8e-08 33.3 0.0 1.6e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 PVD39317.1 - 1.9e-07 31.3 0.0 5.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PVD39317.1 - 4.1e-06 27.2 0.1 8.7e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 PVD39317.1 - 6.7e-05 22.7 1.0 0.00014 21.7 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.15 PVD39317.1 - 0.0011 18.5 1.5 0.0037 16.9 1.5 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf-C2H2_jaz PF12171.8 PVD39317.1 - 0.0017 18.6 3.4 0.0042 17.3 3.4 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PhoH PF02562.16 PVD39317.1 - 0.0018 17.8 0.1 0.0098 15.4 0.1 2.0 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 PVD39317.1 - 0.0047 17.2 0.1 0.043 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 PVD39317.1 - 0.0079 16.1 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 PVD39317.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.7 3 1 0 3 3 2 0 UvrD/REP helicase N-terminal domain zf-CCCH_4 PF18044.1 PVD39317.1 - 0.047 13.5 0.6 0.091 12.6 0.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger AAA_24 PF13479.6 PVD39317.1 - 0.073 12.8 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4187 PF13821.6 PVD39317.1 - 0.081 12.7 1.4 0.19 11.5 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-met PF12874.7 PVD39317.1 - 0.089 13.2 2.2 0.28 11.6 2.2 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AAA_16 PF13191.6 PVD39317.1 - 0.11 12.9 0.1 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 PVD39317.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AKAP95 PF04988.12 PVD39317.1 - 0.96 9.7 3.6 2.4 8.4 3.6 1.7 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) NCKAP5 PF15246.6 PVD39319.1 - 0.065 12.8 4.6 0.12 11.9 4.6 1.5 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein bZIP_1 PF00170.21 PVD39319.1 - 3.1 8.0 18.0 5.4 7.2 18.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor PRKG1_interact PF15898.5 PVD39321.1 - 0.00082 20.2 8.5 0.0018 19.2 8.5 1.5 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 PVD39321.1 - 0.06 13.4 21.3 0.088 12.9 18.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 PVD39321.1 - 0.069 13.7 10.7 0.14 12.7 10.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor BRE1 PF08647.11 PVD39321.1 - 0.072 13.2 9.6 0.12 12.5 9.6 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fmp27_WPPW PF10359.9 PVD39321.1 - 0.19 10.5 6.8 0.26 10.1 6.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2514 PF10721.9 PVD39321.1 - 0.38 10.8 4.3 0.56 10.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Phlebovirus_NSM PF07246.11 PVD39321.1 - 2.7 7.3 6.3 3.8 6.8 6.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FtsL PF04999.13 PVD39321.1 - 4.3 7.4 6.3 9.7 6.3 6.3 1.5 1 0 0 1 1 1 0 Cell division protein FtsL V_ATPase_I PF01496.19 PVD39321.1 - 5.9 4.7 5.0 7 4.4 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_TM PF12794.7 PVD39321.1 - 6.7 5.5 6.1 9.8 4.9 6.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Presenilin PF01080.17 PVD39321.1 - 9.9 4.8 7.4 12 4.5 7.4 1.2 1 0 0 1 1 1 0 Presenilin Homeodomain PF00046.29 PVD39323.1 - 0.13 12.1 3.1 0.26 11.2 3.1 1.5 1 0 0 1 1 1 0 Homeodomain C2 PF00168.30 PVD39324.1 - 4.1e-37 126.6 0.2 4.5e-18 65.4 0.0 4.3 3 1 0 3 3 3 3 C2 domain Membr_traf_MHD PF10540.9 PVD39324.1 - 1.3e-10 41.7 3.8 3.4e-05 24.1 0.6 3.4 2 2 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain COesterase PF00135.28 PVD39326.1 - 2.9e-80 270.6 0.0 4e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD39326.1 - 2.8e-06 27.4 0.1 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PVD39326.1 - 0.049 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 PVD39327.1 - 4.2e-86 289.8 0.0 4.8e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PVD39327.1 - 2.1e-08 34.3 0.0 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_S8 PF00410.19 PVD39329.1 - 1.6e-20 73.4 0.0 2.2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 HEAT_2 PF13646.6 PVD39330.1 - 4.2e-20 71.9 1.7 4.1e-09 36.7 0.2 3.6 3 0 0 3 3 3 3 HEAT repeats HEAT PF02985.22 PVD39330.1 - 1.1e-10 40.8 0.3 0.0085 16.3 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.16 PVD39330.1 - 0.00016 22.0 3.8 44 5.2 0.1 5.2 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Kringle PF00051.18 PVD39330.1 - 0.0061 16.9 0.1 5.3 7.4 0.1 2.8 2 0 0 2 2 2 2 Kringle domain 7tm_1 PF00001.21 PVD39332.1 - 5e-55 186.6 21.4 5e-55 186.6 21.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD39332.1 - 1.6e-15 57.2 19.6 2.3e-15 56.7 19.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD39332.1 - 4.5e-07 29.7 16.3 4.5e-07 29.7 16.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 PVD39332.1 - 0.02 14.6 14.9 0.077 12.7 14.9 1.9 1 1 0 1 1 1 0 Olfactory receptor DPM3 PF08285.11 PVD39332.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.0 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3671 PF12420.8 PVD39332.1 - 0.29 11.2 9.2 0.2 11.8 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function Orthopox_A36R PF05950.11 PVD39332.1 - 0.41 10.8 2.9 0.99 9.6 2.9 1.6 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DM PF00751.18 PVD39333.1 - 2.6e-19 68.8 33.6 9.8e-11 41.4 6.4 3.6 3 0 0 3 3 3 3 DM DNA binding domain IPU_b_solenoid PF18783.1 PVD39334.1 - 9.3e-05 22.4 5.1 0.00027 20.9 5.1 1.9 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat Pkinase PF00069.25 PVD39335.1 - 3e-40 138.3 0.0 5.8e-40 137.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39335.1 - 1.4e-23 83.5 0.0 1.9e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PVD39335.1 - 1.1e-07 31.4 0.2 1.8e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PVD39335.1 - 0.0023 17.9 1.4 0.14 12.1 0.5 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PVD39335.1 - 0.08 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PVD39335.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_49N PF17433.2 PVD39336.1 - 1.4e-05 24.9 0.2 3.6e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain IPU_b_solenoid PF18783.1 PVD39336.1 - 0.0065 16.5 4.4 0.02 14.9 4.4 1.9 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat Beta_helix PF13229.6 PVD39336.1 - 0.01 15.7 4.2 0.01 15.7 4.2 2.5 2 1 1 3 3 3 0 Right handed beta helix region Glyco_hydro_49 PF03718.13 PVD39336.1 - 0.033 14.2 1.8 0.073 13.1 0.2 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 Pectate_lyase_3 PF12708.7 PVD39336.1 - 0.86 9.4 13.4 0.044 13.6 3.4 3.4 2 2 3 5 5 5 0 Pectate lyase superfamily protein IPU_b_solenoid PF18783.1 PVD39337.1 - 0.048 13.7 5.7 0.14 12.2 5.7 1.9 1 0 0 1 1 1 0 Isopullulanase beta-solenoid repeat IPU_b_solenoid PF18783.1 PVD39338.1 - 5.5e-05 23.1 4.8 0.0002 21.3 4.8 2.1 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat Beta_helix PF13229.6 PVD39338.1 - 0.011 15.5 14.2 0.015 15.2 9.3 2.9 2 1 1 3 3 3 0 Right handed beta helix region Tet_JBP PF12851.7 PVD39339.1 - 3.5e-97 325.8 16.0 3.5e-97 325.8 16.0 3.3 2 2 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF3797 PF12677.7 PVD39340.1 - 1 9.3 3.9 0.3 11.0 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Pkinase PF00069.25 PVD39341.1 - 7.2e-20 71.5 0.0 1.8e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39341.1 - 3.9e-06 26.3 0.0 1.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase WAPL PF07814.13 PVD39341.1 - 0.0012 17.8 6.0 0.0012 17.7 3.1 2.5 2 1 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin HEAT_EZ PF13513.6 PVD39341.1 - 0.0048 17.4 10.1 1.4 9.5 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat RICTOR_N PF14664.6 PVD39341.1 - 0.0086 15.1 6.0 0.036 13.0 1.0 3.3 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Arm PF00514.23 PVD39341.1 - 0.023 14.8 1.4 4.1 7.6 0.0 3.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD39341.1 - 0.023 15.1 7.0 18 5.8 0.0 5.8 7 0 0 7 7 7 0 HEAT repeats HEAT PF02985.22 PVD39341.1 - 0.51 10.7 11.1 0.66 10.4 0.1 5.0 6 0 0 6 6 6 0 HEAT repeat Stk19 PF10494.9 PVD39342.1 - 3e-41 141.7 0.2 3.7e-41 141.4 0.2 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PLDc_2 PF13091.6 PVD39343.1 - 9.2e-26 90.3 0.8 1e-25 90.1 0.8 1.0 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 PVD39343.1 - 6.8e-05 22.6 1.3 0.00054 19.6 1.3 1.9 1 1 0 1 1 1 1 FAM83 A-H PLDc PF00614.22 PVD39343.1 - 0.0057 16.8 0.1 0.0057 16.8 0.1 2.5 3 0 0 3 3 3 1 Phospholipase D Active site motif PPR_3 PF13812.6 PVD39344.1 - 7.1e-31 106.1 1.3 1e-06 28.7 0.3 6.4 5 1 1 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 PVD39344.1 - 2e-28 98.3 11.5 1e-11 44.9 0.2 9.2 7 3 3 10 10 10 6 PPR repeat family PPR_1 PF12854.7 PVD39344.1 - 1e-16 60.3 0.1 2e-06 27.4 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 PVD39344.1 - 9.4e-14 51.3 0.1 2.6e-06 27.0 0.0 3.6 2 2 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PVD39344.1 - 6.5e-12 44.8 10.2 2.7e-06 27.2 0.2 6.7 5 1 0 5 5 5 2 PPR repeat ATP13 PF12921.7 PVD39344.1 - 0.00016 21.5 0.0 0.031 14.2 0.0 2.7 1 1 1 2 2 2 1 Mitochondrial ATPase expression Exog_C PF18026.1 PVD39344.1 - 0.59 10.2 6.3 5.7 7.1 0.1 4.1 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain SET PF00856.28 PVD39346.1 - 1.5e-19 71.0 1.7 9.2e-19 68.4 0.4 2.8 2 1 0 2 2 2 1 SET domain PRC2_HTH_1 PF18118.1 PVD39346.1 - 1.6e-17 64.1 0.1 1.6e-17 64.1 0.1 3.3 2 2 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain preSET_CXC PF18264.1 PVD39346.1 - 1.2e-11 44.8 16.5 1.2e-11 44.8 16.5 3.7 2 1 0 2 2 2 1 CXC domain 7tm_1 PF00001.21 PVD39348.1 - 4.8e-22 78.5 8.0 3.8e-13 49.4 3.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD39348.1 - 0.065 12.5 1.6 0.071 12.4 0.1 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw LRR_4 PF12799.7 PVD39349.1 - 1.5e-34 117.4 32.8 9.7e-08 32.2 0.9 6.6 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD39349.1 - 1.4e-27 95.2 26.1 1.2e-08 34.6 4.5 5.6 2 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 PVD39349.1 - 1.1e-20 73.8 5.7 1.4e-08 34.4 1.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 PVD39349.1 - 4.8e-09 35.6 20.9 0.0076 16.2 0.2 9.7 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 PVD39349.1 - 3.6e-07 29.8 27.1 3 8.7 0.2 10.3 10 0 0 10 10 10 3 Leucine Rich Repeat Ras PF00071.22 PVD39350.1 - 6.1e-40 136.5 0.1 7.8e-40 136.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD39350.1 - 1.6e-15 57.4 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PVD39350.1 - 0.00042 19.8 0.1 0.00052 19.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family 4HFCP_synth PF04476.13 PVD39350.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 4-HFC-P synthase SRPRB PF09439.10 PVD39350.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PVD39350.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4605 PF15378.6 PVD39352.1 - 1e-20 73.3 6.3 1.3e-20 72.9 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Glyco_hydro_57 PF03065.15 PVD39353.1 - 0.028 13.6 0.1 0.059 12.5 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 HEAT PF02985.22 PVD39353.1 - 0.036 14.3 1.0 48 4.6 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat IFRD PF05004.13 PVD39353.1 - 0.036 13.2 3.7 11 5.0 0.0 4.3 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 PVD39353.1 - 0.068 13.4 0.0 0.54 10.4 0.0 2.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 PVD39353.1 - 0.15 12.1 1.4 2 8.4 0.0 3.3 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PVD39353.1 - 0.64 10.4 3.7 19 5.7 0.3 4.2 4 1 0 4 4 4 0 HEAT repeats WD40 PF00400.32 PVD39354.1 - 5.5e-38 128.3 55.2 0.0038 18.0 0.1 19.9 20 1 1 21 21 21 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD39354.1 - 7.7e-23 80.6 2.1 0.034 14.4 0.0 12.3 9 3 2 12 12 12 6 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 PVD39354.1 - 1.8e-15 57.2 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) eIF2A PF08662.11 PVD39354.1 - 2.3e-07 30.9 0.2 2.4 8.0 0.0 6.8 6 3 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A HELP PF03451.14 PVD39354.1 - 1.2e-06 28.3 0.0 0.066 13.1 0.0 2.7 2 0 0 2 2 2 2 HELP motif Nup160 PF11715.8 PVD39354.1 - 0.00065 18.5 4.8 0.016 13.9 0.1 4.3 3 2 0 4 4 4 1 Nucleoporin Nup120/160 POT1PC PF16686.5 PVD39354.1 - 0.0045 16.9 0.4 44 3.9 0.1 4.2 3 1 1 4 4 4 0 ssDNA-binding domain of telomere protection protein PQQ_2 PF13360.6 PVD39354.1 - 0.017 14.7 3.3 1.2 8.6 0.0 4.0 4 1 0 4 4 4 0 PQQ-like domain Frtz PF11768.8 PVD39354.1 - 0.085 11.2 0.6 0.19 10.0 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 PVD39354.1 - 0.22 10.5 0.2 6.9 5.6 0.0 3.2 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain CH PF00307.31 PVD39355.1 - 1e-24 86.8 0.0 2.3e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PVD39355.1 - 2.4e-09 36.9 0.0 5.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain DUF3585 PF12130.8 PVD39356.1 - 4.5e-35 120.7 20.1 6.7e-35 120.2 20.1 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain UPF0193 PF05250.11 PVD39357.1 - 1.4e-54 185.2 6.8 2e-54 184.7 6.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) 7tm_1 PF00001.21 PVD39358.1 - 2.9e-29 102.2 19.3 3.8e-29 101.8 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 PVD39358.1 - 3.4e-06 26.9 16.2 5.1e-06 26.3 16.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD39358.1 - 0.011 15.1 11.0 0.014 14.8 11.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srh PF10318.9 PVD39358.1 - 0.35 9.9 14.1 0.63 9.0 14.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh AMP-binding PF00501.28 PVD39359.1 - 2.2e-76 257.2 0.0 1e-75 255.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PVD39359.1 - 6.7e-07 30.2 0.1 1.9e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCCH PF00642.24 PVD39359.1 - 1.7e-06 27.7 2.0 7.7e-05 22.5 0.5 5.9 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PVD39359.1 - 0.00028 20.8 24.3 0.069 13.2 0.2 5.8 5 0 0 5 5 5 2 Zinc finger domain Kri1 PF05178.12 PVD39359.1 - 1.8 9.2 5.4 4 8.1 5.4 1.6 1 0 0 1 1 1 0 KRI1-like family Inhibitor_I36 PF03995.13 PVD39359.1 - 1.9 8.5 5.5 9 6.3 0.0 3.7 3 0 0 3 3 3 0 Peptidase inhibitor family I36 Fibrinogen_C PF00147.18 PVD39360.1 - 6.1e-41 140.6 0.0 9e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD39360.1 - 0.00059 19.7 4.9 0.0011 18.9 4.9 1.4 1 0 0 1 1 1 1 PAN domain hEGF PF12661.7 PVD39360.1 - 0.0056 17.3 3.6 0.023 15.3 3.6 2.2 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 PVD39360.1 - 0.043 14.2 4.1 0.043 14.2 4.1 2.3 2 0 0 2 2 2 0 EGF-like domain cEGF PF12662.7 PVD39360.1 - 0.44 10.5 5.3 0.9 9.5 2.8 2.8 1 1 1 2 2 2 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 PVD39360.1 - 0.6 10.3 8.9 2.4 8.4 8.9 2.1 1 1 0 1 1 1 0 Laminin EGF domain LSM PF01423.22 PVD39361.1 - 8.1e-09 35.1 0.1 2.8e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 LSM domain DUF4515 PF14988.6 PVD39362.1 - 2.6e-33 115.6 41.6 2.6e-33 115.6 41.6 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) DUF4618 PF15397.6 PVD39362.1 - 0.013 15.0 45.4 0.0073 15.8 43.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Pox_A_type_inc PF04508.12 PVD39362.1 - 0.12 12.3 0.3 0.12 12.3 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat kleA_kleC PF17383.2 PVD39362.1 - 0.43 10.9 17.1 0.62 10.4 1.4 3.6 3 1 0 3 3 3 0 Uncharacterized KorC regulated protein A IQ PF00612.27 PVD39363.1 - 0.00049 19.7 7.0 0.17 11.8 0.7 4.7 4 0 0 4 4 4 2 IQ calmodulin-binding motif COQ7 PF03232.13 PVD39363.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.8 3 1 0 3 3 3 0 Ubiquinone biosynthesis protein COQ7 DUF1192 PF06698.11 PVD39363.1 - 4 7.6 15.1 1.1 9.3 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) YabA PF06156.13 PVD39363.1 - 7.3 7.3 36.8 3.9 8.2 4.7 5.8 3 1 2 5 5 5 0 Initiation control protein YabA PX PF00787.24 PVD39364.1 - 1.9e-19 69.7 1.5 1.9e-19 69.7 1.5 1.7 2 0 0 2 2 2 1 PX domain G-alpha PF00503.20 PVD39365.1 - 1.2e-86 291.0 3.1 1.4e-86 290.9 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PVD39365.1 - 4.8e-11 42.4 0.1 1.4e-10 40.9 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PVD39365.1 - 0.01 15.2 0.2 0.018 14.4 0.2 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PVD39365.1 - 0.058 12.9 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NAD_binding_8 PF13450.6 PVD39366.1 - 6.1e-15 55.2 0.0 1.8e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PVD39366.1 - 1.3e-14 54.4 0.3 1.4e-10 41.1 0.1 2.9 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 PVD39366.1 - 7.2e-07 29.1 2.7 0.0001 22.0 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PVD39366.1 - 4.5e-06 26.7 0.2 8.3e-06 25.9 0.2 1.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PVD39366.1 - 0.0017 17.8 0.3 0.003 17.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 PVD39366.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 PVD39366.1 - 0.03 14.9 0.4 4.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PVD39366.1 - 0.032 13.5 0.4 0.062 12.5 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 PVD39366.1 - 0.13 11.4 0.8 0.56 9.4 0.9 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase USP8_dimer PF08969.11 PVD39367.1 - 9.6e-19 67.7 0.0 2.9e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain JAB PF01398.21 PVD39367.1 - 2.8e-18 66.0 0.0 8.1e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PVD39367.1 - 0.002 17.9 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Cation_ATPase PF13246.6 PVD39367.1 - 0.16 12.1 0.5 0.57 10.3 0.1 2.2 2 0 0 2 2 2 0 Cation transport ATPase (P-type) XRN_M PF17846.1 PVD39367.1 - 2.8 6.8 6.4 4.4 6.1 6.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain PIG-P PF08510.12 PVD39367.1 - 3 7.8 7.1 37 4.3 3.4 2.7 2 0 0 2 2 2 0 PIG-P RhoGAP PF00620.27 PVD39368.1 - 4.2e-22 78.6 0.3 4.6e-21 75.2 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.8 PVD39368.1 - 0.00075 19.2 2.8 0.00075 19.2 2.8 3.8 3 1 0 3 3 3 2 DNA replication and checkpoint protein PilJ PF13675.6 PVD39368.1 - 0.086 12.9 3.3 1.6 8.8 1.3 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin_2 PF01920.20 PVD39368.1 - 0.14 12.1 8.5 2.3 8.2 0.2 3.6 3 0 0 3 3 3 0 Prefoldin subunit AAA_23 PF13476.6 PVD39368.1 - 0.89 10.0 12.2 5.3 7.5 1.9 2.5 2 0 0 2 2 2 0 AAA domain FapA PF03961.13 PVD39368.1 - 1.8 7.1 9.4 3.1 6.3 1.0 2.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF3452 PF11934.8 PVD39368.1 - 2.8 7.5 6.5 0.37 10.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4404 PF14357.6 PVD39368.1 - 7.1 7.3 9.8 1.9 9.2 1.6 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) HLH PF00010.26 PVD39371.1 - 3.1e-15 55.9 0.2 5.8e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 PVD39372.1 - 8e-15 55.0 25.4 0.001 19.8 0.1 9.0 9 0 0 9 9 9 4 WD domain, G-beta repeat EF-hand_8 PF13833.6 PVD39372.1 - 1.7e-06 27.7 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair Nucleoporin_N PF08801.11 PVD39372.1 - 1.1e-05 24.5 1.3 0.0082 14.9 0.0 4.2 5 1 0 6 6 6 2 Nup133 N terminal like EF-hand_7 PF13499.6 PVD39372.1 - 3.6e-05 24.1 0.0 8.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 PVD39372.1 - 5.3e-05 23.4 0.1 0.046 14.0 0.0 4.3 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 PVD39372.1 - 0.00094 18.6 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 EF hand Nup160 PF11715.8 PVD39372.1 - 0.017 13.8 4.4 3.9 6.0 0.0 4.3 3 2 1 4 4 4 0 Nucleoporin Nup120/160 EF-hand_6 PF13405.6 PVD39372.1 - 0.029 14.3 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Transposase_24 PF03004.14 PVD39372.1 - 3 7.9 5.4 0.75 9.9 0.4 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Glyco_transf_10 PF00852.19 PVD39373.1 - 6.5e-38 130.2 0.0 1.2e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD39373.1 - 5.9e-09 36.4 0.1 1.6e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal UPAR_LY6_2 PF16975.5 PVD39373.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 FG-GAP PF01839.23 PVD39374.1 - 3.4e-11 43.1 16.0 0.2 11.8 1.0 5.7 5 0 0 5 5 5 5 FG-GAP repeat VCBS PF13517.6 PVD39374.1 - 1.4e-09 38.4 16.0 0.0028 18.2 1.1 5.5 5 2 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 PVD39374.1 - 5.1e-06 26.2 0.9 0.0031 17.4 0.1 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 PVD39374.1 - 0.00012 21.8 0.0 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain TcdB_toxin_midN PF12256.8 PVD39374.1 - 0.012 15.0 0.6 1.8 7.9 0.0 3.8 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 PVD39374.1 - 4.6 7.5 12.4 23 5.3 0.1 4.7 5 0 0 5 5 5 0 Dockerin type I domain Forkhead PF00250.18 PVD39376.1 - 3.1e-37 126.7 0.5 4.9e-37 126.1 0.5 1.3 1 0 0 1 1 1 1 Forkhead domain Wbp11 PF09429.10 PVD39377.1 - 2.4e-20 72.7 8.8 2.4e-20 72.7 8.8 3.5 4 0 0 4 4 4 1 WW domain binding protein 11 SOAR PF16533.5 PVD39377.1 - 0.005 16.8 0.5 0.017 15.1 0.5 1.8 1 0 0 1 1 1 1 STIM1 Orai1-activating region TAN PF11640.8 PVD39377.1 - 0.051 13.7 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair zf-C2H2_4 PF13894.6 PVD39378.1 - 0.032 15.1 0.3 0.032 15.1 0.3 6.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf-SCNM1 PF15803.5 PVD39378.1 - 0.11 12.2 0.8 0.26 10.9 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 DUF4187 PF13821.6 PVD39378.1 - 0.13 12.0 7.5 0.038 13.8 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) SAGA-Tad1 PF12767.7 PVD39378.1 - 0.24 11.1 0.0 0.24 11.1 0.0 3.1 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-C2H2_2 PF12756.7 PVD39378.1 - 8.1 6.9 17.3 4.5 7.7 0.6 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) MARVEL PF01284.23 PVD39379.1 - 3.3e-23 82.3 9.4 4.1e-23 82.0 9.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Amastin PF07344.11 PVD39379.1 - 0.02 14.8 3.5 3.3 7.5 1.3 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein LPG_synthase_TM PF03706.13 PVD39379.1 - 0.023 14.2 3.7 0.031 13.8 3.7 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region NB PF04159.13 PVD39379.1 - 0.043 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 NB glycoprotein TSSC4 PF15264.6 PVD39379.1 - 0.1 12.8 0.1 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 DctQ PF04290.12 PVD39379.1 - 2.3 8.2 8.7 0.61 10.0 0.6 2.7 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Chordopox_A33R PF05966.12 PVD39380.1 - 0.002 17.5 2.5 0.0027 17.0 2.4 1.3 1 1 0 1 1 1 1 Chordopoxvirus A33R protein QVR PF17064.5 PVD39380.1 - 0.0066 16.7 10.3 0.01 16.1 10.3 1.3 1 0 0 1 1 1 1 Sleepless protein DAP10 PF07213.11 PVD39380.1 - 0.14 12.2 1.1 2.5 8.1 0.2 2.2 2 0 0 2 2 2 0 DAP10 membrane protein UPAR_LY6 PF00021.21 PVD39380.1 - 5.8 7.7 13.0 8.1 7.2 13.0 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Metallophos PF00149.28 PVD39381.1 - 2.3e-39 136.0 0.0 3.7e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 PVD39381.1 - 0.0034 16.8 0.1 0.005 16.2 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) Ribosomal_S5 PF00333.20 PVD39382.1 - 4.1e-31 106.8 0.6 7.9e-31 105.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PVD39382.1 - 4.4e-25 86.9 0.0 7.1e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 PVD39382.1 - 5.1 7.7 19.2 13 6.4 19.2 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Exo_endo_phos PF03372.23 PVD39383.1 - 1.8e-19 70.2 0.0 4.7e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Band_7 PF01145.25 PVD39384.1 - 9e-13 48.6 0.0 4.3e-12 46.4 0.0 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Spectrin PF00435.21 PVD39384.1 - 0.17 12.4 3.5 0.26 11.8 3.5 1.2 1 0 0 1 1 1 0 Spectrin repeat TPR_1 PF00515.28 PVD39385.1 - 3.3e-44 147.0 4.7 1.1e-09 37.7 0.1 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 PVD39385.1 - 8.7e-35 116.0 5.7 1e-06 28.4 0.1 9.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 PVD39385.1 - 2.4e-26 89.7 5.8 8.9e-05 22.4 0.1 9.0 10 0 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD39385.1 - 5.1e-24 84.3 23.4 4e-20 71.8 4.4 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PVD39385.1 - 1.5e-22 79.6 8.5 2.4e-06 27.7 0.1 7.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 PVD39385.1 - 9.6e-22 76.4 2.5 0.00016 21.3 0.4 7.1 4 1 3 7 7 7 5 TPR repeat TPR_19 PF14559.6 PVD39385.1 - 1.7e-21 76.5 12.5 0.00079 19.9 0.1 7.6 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 PVD39385.1 - 5.8e-18 64.1 1.3 0.011 16.5 0.0 8.7 3 2 4 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 PVD39385.1 - 3e-17 63.0 2.5 2e-06 28.3 0.0 6.8 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 PVD39385.1 - 8.5e-14 51.2 11.6 0.12 13.0 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD39385.1 - 3e-12 46.0 9.1 0.032 14.6 0.1 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 PVD39385.1 - 3e-11 42.5 3.9 0.017 15.1 0.0 7.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PVD39385.1 - 1.5e-08 34.2 0.3 0.16 11.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PVD39385.1 - 3.5e-07 30.3 0.0 0.11 12.7 0.0 6.0 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD39385.1 - 2.1e-05 24.1 2.5 0.014 14.8 0.2 3.4 3 1 0 3 3 3 2 MalT-like TPR region TPR_15 PF13429.6 PVD39385.1 - 2.6e-05 23.6 1.4 1.9 7.6 0.0 4.5 2 2 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 PVD39385.1 - 0.009 16.2 1.5 16 6.0 0.0 4.9 7 0 0 7 7 5 0 PPR repeat ChAPs PF09295.10 PVD39385.1 - 0.11 11.4 0.2 0.57 9.1 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 PVD39385.1 - 0.15 12.7 1.0 36 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 PVD39385.1 - 0.27 11.6 5.7 46 4.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Antimicrobial25 PF16839.5 PVD39386.1 - 0.45 10.6 5.4 0.8 9.8 5.4 1.7 1 1 0 1 1 1 0 Nematode antimicrobial peptide DPPIV_N PF00930.21 PVD39389.1 - 8.9e-74 248.4 4.2 1.2e-66 224.9 0.9 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 PVD39389.1 - 2.2e-48 164.6 1.6 3e-48 164.1 0.4 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family ANAPC4_WD40 PF12894.7 PVD39389.1 - 0.0077 16.5 0.0 5.2 7.4 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_4 PF12146.8 PVD39389.1 - 0.024 13.9 0.1 0.17 11.1 0.1 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 PVD39389.1 - 0.029 13.7 0.4 0.052 12.9 0.4 1.3 1 0 0 1 1 1 0 Secretory lipase DUF3139 PF11337.8 PVD39389.1 - 0.032 14.9 0.1 2.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Peptidase_S15 PF02129.18 PVD39389.1 - 0.034 13.7 0.7 0.063 12.9 0.7 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF872 PF05915.12 PVD39389.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Abhydrolase_6 PF12697.7 PVD39389.1 - 0.058 14.0 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PVD39389.1 - 0.17 11.5 0.6 0.56 9.8 0.1 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Transcrip_act PF04949.13 PVD39390.1 - 5.6e-06 26.3 18.6 1.2e-05 25.2 18.6 1.5 1 0 0 1 1 1 1 Transcriptional activator Alpha-amylase PF00128.24 PVD39390.1 - 0.04 13.5 7.1 0.062 12.9 7.1 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF630 PF04783.12 PVD39390.1 - 0.16 12.1 1.3 0.41 10.8 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) DUF1327 PF07041.11 PVD39390.1 - 0.17 11.9 2.5 0.13 12.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) Ntox1 PF15500.6 PVD39390.1 - 2.4 8.5 7.2 1.5 9.2 4.1 2.3 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 zf-C4 PF00105.18 PVD39392.1 - 2.9e-15 56.5 3.7 7.2e-15 55.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 PVD39392.1 - 8.3e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SR-25 PF10500.9 PVD39393.1 - 4.5 6.8 16.0 0.26 10.9 11.0 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pyridoxal_deC PF00282.19 PVD39395.1 - 6.3e-07 28.4 0.1 3e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PVD39395.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 PVD39397.1 - 1.4e-18 66.9 20.0 3.1e-07 31.0 0.5 6.9 8 0 0 8 8 6 3 WD domain, G-beta repeat zf-TRAF PF02176.18 PVD39397.1 - 2.2e-10 41.1 7.9 2.3e-10 41.0 3.6 2.8 2 1 0 2 2 2 1 TRAF-type zinc finger zf-RING_UBOX PF13445.6 PVD39397.1 - 3.7e-07 30.0 5.4 3.7e-07 30.0 5.4 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PVD39397.1 - 6.3e-07 29.1 6.5 2.5e-06 27.2 5.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PVD39397.1 - 1.6e-06 28.1 5.1 7.4e-06 26.0 5.1 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PVD39397.1 - 8.2e-06 25.6 5.5 4.8e-05 23.2 5.5 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PVD39397.1 - 2.4e-05 24.1 3.8 0.00012 21.9 3.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PVD39397.1 - 4.6e-05 23.3 5.9 4.6e-05 23.3 5.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-ACC PF17848.1 PVD39397.1 - 6.4e-05 22.9 0.9 0.25 11.5 0.1 3.0 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain Prok-RING_4 PF14447.6 PVD39397.1 - 7.8e-05 22.5 5.0 7.8e-05 22.5 5.0 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 WD40_like PF17005.5 PVD39397.1 - 0.00011 21.7 0.2 0.00054 19.4 0.2 2.0 1 1 0 1 1 1 1 WD40-like domain zf-TRAF_2 PF15965.5 PVD39397.1 - 0.00012 22.4 4.9 0.00012 22.4 4.9 3.9 4 1 1 5 5 2 2 TRAF-like zinc-finger Sina PF03145.16 PVD39397.1 - 0.00017 21.6 8.9 0.0047 16.9 0.7 2.5 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_6 PF14835.6 PVD39397.1 - 0.00087 19.1 1.6 0.0026 17.6 1.6 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF1664 PF07889.12 PVD39397.1 - 0.014 15.4 3.6 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.6 PVD39397.1 - 0.019 15.3 5.3 0.019 15.3 5.3 3.3 4 0 0 4 4 1 0 Ring finger domain Filament PF00038.21 PVD39397.1 - 0.028 14.0 1.1 0.046 13.3 1.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein PKcGMP_CC PF16808.5 PVD39397.1 - 0.036 13.9 0.2 0.036 13.9 0.2 1.7 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tropomyosin_1 PF12718.7 PVD39397.1 - 0.051 13.7 2.2 0.088 13.0 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.11 PVD39397.1 - 0.091 11.6 0.2 0.16 10.8 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 PVD39397.1 - 0.093 13.1 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-RING_10 PF16685.5 PVD39397.1 - 0.096 12.8 3.6 0.47 10.6 3.6 2.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Syntaxin-6_N PF09177.11 PVD39397.1 - 0.12 13.0 0.7 0.25 11.9 0.7 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal zf-U11-48K PF05253.12 PVD39397.1 - 0.15 12.0 2.6 23 5.0 0.0 3.8 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger CCDC154 PF15450.6 PVD39397.1 - 0.38 9.3 5.5 0.55 8.7 5.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 eIF-3_zeta PF05091.12 PVD39398.1 - 3.6e-182 607.0 7.2 1.7e-95 321.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 PVD39398.1 - 0.00042 19.9 0.0 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus Apyrase PF06079.11 PVD39399.1 - 5.8e-122 406.5 0.0 7e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 Apyrase Ribosomal_L1 PF00687.21 PVD39400.1 - 4.1e-38 131.2 0.0 4.1e-38 131.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Elongin_A PF06881.11 PVD39400.1 - 7 7.2 12.6 1.7 9.2 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ank_4 PF13637.6 PVD39401.1 - 1.4e-14 54.3 0.2 1.8e-07 31.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PVD39401.1 - 1.2e-09 38.2 0.3 2.1e-08 34.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD39401.1 - 1.6e-08 35.0 0.0 2.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PVD39401.1 - 4.1e-08 32.9 0.0 1.3e-05 25.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PVD39401.1 - 2.5e-06 27.7 1.3 4.6e-06 26.8 0.1 2.1 3 0 0 3 3 3 1 Ankyrin repeat RRM_1 PF00076.22 PVD39402.1 - 8.1e-32 108.9 0.1 2.1e-16 59.5 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PVD39402.1 - 4.3e-05 23.5 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Pkinase PF00069.25 PVD39403.1 - 1.1e-57 195.4 0.0 1.4e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39403.1 - 6.3e-42 143.7 0.0 8e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PVD39403.1 - 3.4e-05 23.3 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PVD39403.1 - 0.00016 20.8 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PVD39403.1 - 0.0048 16.0 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 PVD39403.1 - 0.014 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PVD39403.1 - 0.023 13.5 0.0 0.046 12.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF4344 PF14247.6 PVD39403.1 - 0.055 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase APH PF01636.23 PVD39403.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PVD39403.1 - 0.11 11.4 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tweety PF04906.13 PVD39404.1 - 1.6e-34 119.3 7.2 3.4e-28 98.4 3.0 3.0 1 1 2 3 3 3 3 Tweety Corona_NS3b PF03053.14 PVD39404.1 - 0.032 14.0 1.3 0.052 13.3 1.3 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein RanGAP1_C PF07834.11 PVD39404.1 - 0.13 11.9 3.3 0.15 11.7 0.4 2.2 2 1 1 3 3 3 0 RanGAP1 C-terminal domain DUF4131 PF13567.6 PVD39404.1 - 3.8 7.1 5.6 1.2 8.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PKD_channel PF08016.12 PVD39405.1 - 2.4e-73 247.3 13.3 4.8e-73 246.3 13.3 1.5 1 0 0 1 1 1 1 Polycystin cation channel REJ PF02010.15 PVD39405.1 - 3.3e-49 167.9 2.9 3.3e-49 167.9 2.9 2.4 3 0 0 3 3 3 1 REJ domain PLAT PF01477.23 PVD39405.1 - 1.1e-21 77.6 0.1 4.4e-21 75.6 0.1 2.1 1 0 0 1 1 1 1 PLAT/LH2 domain PKD PF00801.20 PVD39405.1 - 3.6e-13 49.2 4.8 3.5e-07 30.0 0.3 3.5 3 0 0 3 3 3 2 PKD domain GPS PF01825.21 PVD39405.1 - 6.7e-07 29.7 2.7 2.1e-06 28.1 2.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PKD_3 PF16820.5 PVD39405.1 - 0.017 14.9 0.4 3.5 7.4 0.0 3.8 4 0 0 4 4 4 0 PKD-like domain BiPBP_C PF06832.12 PVD39405.1 - 0.026 14.5 0.0 0.87 9.7 0.0 3.0 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Cadherin_C_2 PF16492.5 PVD39405.1 - 0.39 11.5 3.6 76 4.1 0.0 4.3 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal PKD PF00801.20 PVD39406.1 - 3.3e-20 71.7 10.8 5.7e-08 32.5 0.9 4.2 4 0 0 4 4 4 3 PKD domain Lectin_C PF00059.21 PVD39406.1 - 3.1e-17 63.3 1.8 2.3e-12 47.6 0.6 2.6 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 PVD39406.1 - 0.0014 18.3 0.5 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Ig_3 PF13927.6 PVD39406.1 - 0.025 15.2 2.6 5.8 7.6 0.0 4.7 5 0 0 5 5 5 0 Immunoglobulin domain Y_Y_Y PF07495.13 PVD39406.1 - 0.074 13.0 0.3 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 Y_Y_Y domain FNIP_M PF14637.6 PVD39407.1 - 1.9e-81 273.4 0.0 3.4e-81 272.5 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 PVD39407.1 - 3.1e-59 199.8 0.3 8.1e-59 198.5 0.3 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 PVD39407.1 - 4.2e-08 34.3 0.3 4.2e-08 34.3 0.3 3.6 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus Get5_bdg PF16843.5 PVD39407.1 - 0.15 11.5 0.1 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein LRR_6 PF13516.6 PVD39408.1 - 2.5e-16 58.3 1.3 0.0072 16.3 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 PVD39408.1 - 4.1e-06 27.0 1.3 0.16 12.4 0.0 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PVD39408.1 - 8.8e-05 22.3 0.2 8.8e-05 22.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PVD39408.1 - 0.0023 17.8 1.3 0.0096 15.8 0.1 2.5 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 PVD39408.1 - 0.11 12.2 1.0 12 5.7 0.2 3.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 PVD39408.1 - 0.23 12.2 8.0 0.3 11.8 0.0 4.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 PVD39409.1 - 5.2e-05 23.5 0.1 0.0042 17.5 0.0 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PVD39409.1 - 0.00037 20.2 0.1 0.0017 18.1 0.1 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 PVD39409.1 - 0.0011 19.2 3.0 1 10.2 0.3 3.3 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 PVD39409.1 - 0.0048 16.8 0.0 8.7 6.7 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeat CTP_transf_like PF01467.26 PVD39410.1 - 2.1e-41 141.5 0.2 3e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like COQ7 PF03232.13 PVD39411.1 - 8e-73 243.8 0.0 9.3e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 PVD39411.1 - 0.0076 16.6 0.2 0.058 13.8 0.1 2.0 1 1 1 2 2 2 1 Rubrerythrin SOCS_box PF07525.16 PVD39412.1 - 4.3e-05 23.8 2.9 4.3e-05 23.8 2.9 2.2 2 0 0 2 2 2 1 SOCS box Ank_2 PF12796.7 PVD39414.1 - 3.3e-64 213.4 10.9 7.3e-19 68.1 0.3 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD39414.1 - 8.4e-35 118.7 0.9 1.7e-11 44.4 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PVD39414.1 - 8.7e-31 105.0 4.4 3.2e-07 30.5 0.1 6.5 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PVD39414.1 - 4.6e-30 100.3 0.9 1.1e-05 25.4 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 PVD39414.1 - 1.3e-23 82.7 5.4 4.2e-09 36.5 0.2 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 PVD39414.1 - 6.1e-07 29.7 2.6 1.7e-06 28.2 2.6 1.8 1 0 0 1 1 1 1 SOCS box Shigella_OspC PF06128.11 PVD39414.1 - 0.1 12.3 0.1 0.57 9.9 0.1 2.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein TPR_1 PF00515.28 PVD39415.1 - 6.5e-46 152.4 34.0 1.7e-07 30.8 1.1 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 PVD39415.1 - 3.7e-43 142.2 29.5 1.8e-06 27.6 0.1 9.7 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 PVD39415.1 - 7.1e-28 94.5 24.6 7.2e-06 25.8 0.4 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 PVD39415.1 - 1.8e-26 91.5 16.8 2.9e-08 33.2 1.1 8.1 5 2 3 8 8 8 5 TPR repeat DnaJ PF00226.31 PVD39415.1 - 2.6e-23 81.9 4.2 2.6e-23 81.9 4.2 2.6 2 0 0 2 2 1 1 DnaJ domain TPR_12 PF13424.6 PVD39415.1 - 2e-20 72.8 22.5 2e-06 28.0 0.8 8.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 PVD39415.1 - 3.9e-18 65.7 17.1 0.00027 21.4 0.6 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 PVD39415.1 - 1.5e-16 60.7 9.1 0.00052 20.6 0.1 5.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 PVD39415.1 - 2.6e-15 55.8 7.3 0.24 12.3 0.1 8.4 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 PVD39415.1 - 6.5e-13 48.6 8.8 0.067 13.3 0.1 5.8 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PVD39415.1 - 7.3e-10 38.5 24.4 0.00062 20.0 0.2 8.4 10 0 0 10 10 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PVD39415.1 - 4.1e-09 36.5 25.2 0.00017 21.7 0.7 5.2 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PVD39415.1 - 4.8e-09 35.6 11.3 0.057 13.5 0.3 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 PVD39415.1 - 8.2e-09 35.6 22.7 0.0039 17.7 0.0 8.0 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD39415.1 - 9.5e-08 31.8 1.1 9.5e-08 31.8 1.1 2.9 2 2 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 PVD39415.1 - 5.9e-05 22.8 22.4 1.3 9.0 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat MIT PF04212.18 PVD39415.1 - 9.7e-05 22.4 23.7 0.42 10.7 0.6 7.5 6 1 0 6 6 6 2 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 PVD39415.1 - 0.00053 20.0 5.5 0.35 11.0 0.0 3.9 3 1 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.12 PVD39415.1 - 0.0014 18.5 9.4 0.16 12.0 0.3 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PVD39415.1 - 0.002 17.6 9.0 0.46 10.0 0.1 5.5 6 0 0 6 6 6 1 SHNi-TPR RPT PF13446.6 PVD39415.1 - 0.011 15.7 0.0 0.056 13.4 0.0 2.2 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF627 PF04781.12 PVD39415.1 - 0.015 15.3 5.2 0.23 11.5 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF627) BTAD PF03704.17 PVD39415.1 - 0.12 12.8 8.4 1.2 9.6 1.6 4.0 1 1 3 4 4 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 PVD39415.1 - 0.13 12.4 13.8 8.4 6.6 0.0 6.4 8 1 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat FlbT PF07378.11 PVD39415.1 - 0.39 10.8 5.2 1.2 9.3 2.0 2.8 2 1 1 3 3 3 0 Flagellar protein FlbT Alkyl_sulf_dimr PF14863.6 PVD39415.1 - 0.96 9.9 9.3 3.6 8.0 0.0 4.3 2 1 3 5 5 5 0 Alkyl sulfatase dimerisation DUF357 PF04010.13 PVD39415.1 - 1.2 9.3 6.4 12 6.1 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF357) ANAPC5 PF12862.7 PVD39415.1 - 9.1 6.4 9.2 14 5.8 4.9 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 SlyX PF04102.12 PVD39418.1 - 0.12 13.1 10.1 0.17 12.5 0.3 4.4 3 0 0 3 3 3 0 SlyX TMCO5 PF14992.6 PVD39418.1 - 0.25 10.9 29.6 2.3 7.7 5.0 3.5 2 1 0 2 2 2 0 TMCO5 family Guanylate_cyc PF00211.20 PVD39419.1 - 1.9e-64 216.7 0.6 6.2e-64 215.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PVD39419.1 - 7.2e-30 104.1 0.0 2e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PVD39419.1 - 1.4e-26 93.4 0.0 2.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 PVD39419.1 - 3.1e-23 82.5 0.7 4.8e-23 81.8 0.7 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 PVD39419.1 - 0.023 14.1 2.4 0.047 13.1 2.4 1.5 1 0 0 1 1 1 0 Heme NO binding associated DUF2722 PF10846.8 PVD39421.1 - 1.5e-06 27.4 7.9 1.5e-06 27.4 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PVD39421.1 - 4.7e-05 24.1 2.5 5.7e-05 23.8 2.5 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec62 PF03839.16 PVD39421.1 - 0.0027 17.2 0.3 0.0034 16.9 0.3 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DotU PF09850.9 PVD39421.1 - 0.0048 16.6 0.2 0.0051 16.5 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU DUF3464 PF11947.8 PVD39421.1 - 0.027 14.2 0.7 0.027 14.2 0.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 PVD39421.1 - 0.073 12.8 0.9 0.078 12.7 0.9 1.2 1 0 0 1 1 1 0 Connexin Ctr PF04145.15 PVD39421.1 - 0.079 13.6 0.5 0.083 13.5 0.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF5336 PF17270.2 PVD39421.1 - 0.11 12.2 2.9 0.12 12.0 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Med15 PF09606.10 PVD39421.1 - 0.13 10.9 18.1 0.12 11.0 18.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 PVD39421.1 - 0.32 10.9 7.8 0.33 10.9 7.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 PVD39421.1 - 0.51 10.4 11.0 0.55 10.2 11.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 PVD39421.1 - 0.59 9.7 26.7 0.66 9.6 26.7 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 PVD39421.1 - 0.79 8.3 4.9 0.87 8.2 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 PVD39421.1 - 0.93 9.4 20.8 1 9.3 20.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 PVD39421.1 - 1.3 9.0 4.5 1.5 8.8 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 PVD39421.1 - 1.5 8.2 7.5 1.7 8.1 7.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 PVD39421.1 - 1.5 8.1 11.4 1.6 8.1 11.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Activator_LAG-3 PF11498.8 PVD39421.1 - 1.7 7.5 26.7 2 7.3 26.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 PVD39421.1 - 2 9.4 10.2 2.8 9.0 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 PVD39421.1 - 2.3 7.5 7.5 2.6 7.3 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 PVD39421.1 - 3.3 6.4 9.0 3.9 6.2 9.0 1.1 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 PVD39421.1 - 6 6.7 14.9 6.9 6.5 14.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus SprA-related PF12118.8 PVD39421.1 - 8.2 5.5 18.0 9.3 5.3 18.0 1.0 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.9 PVD39421.1 - 8.3 4.8 16.7 9.3 4.6 16.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Rpp20 PF12328.8 PVD39421.1 - 9.1 6.2 9.7 11 5.9 9.7 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P ANF_receptor PF01094.28 PVD39423.1 - 1.3e-21 77.1 0.4 3.8e-21 75.6 0.4 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region TBPIP PF07106.13 PVD39423.1 - 0.016 15.2 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Peptidase_C26 PF07722.13 PVD39424.1 - 3.7e-10 39.9 0.6 4.7e-05 23.2 0.0 3.4 1 1 1 2 2 2 2 Peptidase C26 GATase PF00117.28 PVD39424.1 - 0.032 14.0 0.0 0.22 11.3 0.0 2.2 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Homeodomain PF00046.29 PVD39425.1 - 4.7e-23 80.8 2.6 1.1e-22 79.7 2.6 1.6 1 0 0 1 1 1 1 Homeodomain Herpes_capsid PF06112.11 PVD39425.1 - 1.5 8.9 8.3 0.17 11.9 3.6 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Herpes_BLLF1 PF05109.13 PVD39426.1 - 2.9e-09 35.5 248.6 0.017 13.1 39.3 7.2 1 1 6 7 7 7 6 Herpes virus major outer envelope glycoprotein (BLLF1) Homeodomain PF00046.29 PVD39427.1 - 2.2e-05 24.2 0.2 4.9e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Homeodomain FAM184 PF15665.5 PVD39428.1 - 2.6e-40 138.5 42.7 2.6e-40 138.5 42.7 7.9 1 1 7 8 8 8 1 Family with sequence similarity 184, A and B DUF3700 PF12481.8 PVD39428.1 - 0.65 9.4 4.2 0.38 10.2 0.7 2.5 2 0 0 2 2 2 0 Aluminium induced protein DUF2746 PF10874.8 PVD39428.1 - 2 8.9 13.6 0.19 12.1 2.1 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2746) ABC_membrane PF00664.23 PVD39429.1 - 6.6e-129 429.4 29.3 2.3e-71 240.7 14.0 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 PVD39429.1 - 2.6e-76 254.7 0.3 1.2e-37 129.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PVD39429.1 - 2e-17 63.3 0.0 7.9e-07 28.7 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PVD39429.1 - 5.8e-11 43.1 1.0 0.00021 21.7 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PVD39429.1 - 6.2e-09 36.2 0.5 0.0083 16.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 PVD39429.1 - 1.2e-08 34.2 1.1 0.0016 17.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 PVD39429.1 - 3e-08 33.2 2.6 0.0072 15.6 0.0 3.9 5 0 0 5 5 5 2 Zeta toxin RsgA_GTPase PF03193.16 PVD39429.1 - 1.7e-07 31.3 0.4 0.036 14.0 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase Rad17 PF03215.15 PVD39429.1 - 2.2e-06 27.7 0.0 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 PVD39429.1 - 2.5e-06 27.5 0.7 0.14 12.2 0.0 4.3 5 0 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 PVD39429.1 - 3e-06 27.7 2.1 0.53 10.7 0.3 4.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 PVD39429.1 - 5.9e-06 25.7 0.0 0.098 11.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 PVD39429.1 - 6.2e-06 26.2 0.0 0.092 12.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 PVD39429.1 - 1.3e-05 24.8 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP-synt_ab PF00006.25 PVD39429.1 - 1.5e-05 24.8 3.7 0.023 14.4 0.0 3.0 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 PVD39429.1 - 2.1e-05 24.3 6.8 0.12 12.1 0.1 4.2 3 2 0 3 3 3 2 AAA domain DUF87 PF01935.17 PVD39429.1 - 2.6e-05 24.4 0.1 0.43 10.6 0.0 3.1 4 0 0 4 4 3 2 Helicase HerA, central domain AAA_29 PF13555.6 PVD39429.1 - 3.6e-05 23.4 0.5 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 PVD39429.1 - 6.1e-05 23.2 4.6 0.41 10.9 0.4 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 PVD39429.1 - 7.8e-05 22.7 0.0 0.038 14.0 0.0 3.5 3 1 1 4 4 4 1 AAA domain DUF815 PF05673.13 PVD39429.1 - 9.8e-05 21.6 0.0 0.49 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 PVD39429.1 - 0.00012 22.4 1.9 4.7 7.4 0.1 3.7 2 2 1 3 3 3 0 AAA domain AAA_24 PF13479.6 PVD39429.1 - 0.00059 19.6 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PVD39429.1 - 0.0013 18.6 0.0 11 5.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 PVD39429.1 - 0.0014 18.4 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 PVD39429.1 - 0.003 17.9 0.0 6.1 7.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 PVD39429.1 - 0.0047 16.7 1.2 3.8 7.2 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein SRP54 PF00448.22 PVD39429.1 - 0.0048 16.5 0.1 1.3 8.7 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain tRNA_lig_kinase PF08303.11 PVD39429.1 - 0.006 16.7 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_18 PF13238.6 PVD39429.1 - 0.0073 16.9 0.2 12 6.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 PVD39429.1 - 0.012 15.2 0.0 4.4 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PVD39429.1 - 0.014 15.3 0.1 8.9 6.2 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 PVD39429.1 - 0.018 15.2 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PVD39429.1 - 0.028 14.3 0.0 6.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 PVD39429.1 - 0.043 13.0 0.2 9.1 5.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Phage_T4_Ndd PF06591.11 PVD39429.1 - 0.069 12.9 0.0 17 5.1 0.0 2.5 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) AAA_19 PF13245.6 PVD39429.1 - 0.076 13.3 0.1 22 5.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PVD39429.1 - 0.11 12.9 3.5 44 4.5 0.6 3.5 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 PVD39429.1 - 0.14 11.5 0.2 12 5.1 0.0 2.5 2 0 0 2 2 2 0 AIG1 family DUF1700 PF08006.11 PVD39429.1 - 2 7.9 6.3 1.5 8.3 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Trypsin PF00089.26 PVD39430.1 - 1.1e-29 103.8 0.2 1.9e-29 103.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PVD39430.1 - 0.0013 19.7 0.0 0.0019 19.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Rib_5-P_isom_A PF06026.14 PVD39431.1 - 1.1e-63 214.0 0.0 1.3e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 PVD39431.1 - 0.00021 20.5 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 PVD39431.1 - 0.00029 20.8 0.1 0.033 14.1 0.1 2.1 1 1 1 2 2 2 2 DeoR C terminal sensor domain WD40 PF00400.32 PVD39432.1 - 1.1e-08 35.5 8.4 0.029 15.3 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 PVD39432.1 - 0.009 16.5 0.4 18 6.0 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 PVD39432.1 - 0.039 13.3 0.0 0.92 8.8 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Spidroin_MaSp PF11260.8 PVD39433.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 HEAT PF02985.22 PVD39434.1 - 2.5e-08 33.5 0.7 0.017 15.4 0.0 3.2 3 0 0 3 3 2 2 HEAT repeat Arm PF00514.23 PVD39434.1 - 3.9e-06 26.7 0.8 0.00093 19.2 0.1 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PVD39434.1 - 1.3e-05 25.5 0.2 0.0009 19.6 0.2 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 PVD39434.1 - 0.00026 21.4 3.7 0.0035 17.8 0.4 2.9 2 1 1 3 3 2 2 HEAT-like repeat Adaptin_N PF01602.20 PVD39434.1 - 0.00063 18.4 0.5 0.0032 16.1 0.0 2.3 1 1 0 2 2 2 1 Adaptin N terminal region DUF4704 PF15787.5 PVD39434.1 - 0.0016 17.7 0.3 0.0082 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Cnd1 PF12717.7 PVD39434.1 - 0.0027 17.8 4.4 0.043 13.9 0.0 3.0 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 COQ7 PF03232.13 PVD39434.1 - 0.022 14.5 1.3 4.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 CDC14 PF08045.11 PVD39434.1 - 0.029 13.5 4.3 0.081 12.0 0.0 2.4 1 1 1 2 2 2 0 Cell division control protein 14, SIN component Globin PF00042.22 PVD39434.1 - 0.066 13.8 0.2 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Globin Prominin PF05478.11 PVD39434.1 - 0.085 10.8 3.5 0.13 10.2 3.5 1.1 1 0 0 1 1 1 0 Prominin Lip_prot_lig_C PF10437.9 PVD39434.1 - 0.087 12.8 2.7 1.7 8.7 0.2 2.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Fes1 PF08609.10 PVD39434.1 - 0.45 11.4 4.3 2.6 9.0 3.9 2.4 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 DUF3213 PF11491.8 PVD39434.1 - 0.51 10.5 3.3 1.4 9.1 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3213) DUF3450 PF11932.8 PVD39434.1 - 0.6 9.4 6.4 1.2 8.3 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ribosomal_S26e PF01283.19 PVD39435.1 - 8.7e-45 151.6 6.6 1.5e-44 150.8 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e Nucleoplasmin PF03066.15 PVD39435.1 - 1.4e-10 41.5 0.0 2.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nucleoplasmin PF03066.15 PVD39436.1 - 3.5e-24 85.2 0.0 6.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain NPL PF17800.1 PVD39436.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.2 2 2 0 2 2 2 0 Nucleoplasmin-like domain FGF PF00167.18 PVD39437.1 - 0.0022 18.1 0.2 0.0025 17.9 0.2 1.1 1 0 0 1 1 1 1 Fibroblast growth factor COX15-CtaA PF02628.15 PVD39440.1 - 2.7e-108 361.9 7.6 3.3e-108 361.6 7.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TRAF6_Z2 PF18048.1 PVD39440.1 - 0.28 11.3 1.4 0.52 10.5 1.4 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Sgf11 PF08209.11 PVD39440.1 - 0.73 9.4 5.8 0.3 10.7 2.0 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CutC PF03932.14 PVD39441.1 - 2.1e-70 236.3 0.4 3.3e-70 235.7 0.4 1.3 1 0 0 1 1 1 1 CutC family PA28_beta PF02252.18 PVD39441.1 - 4.9e-61 204.7 2.3 4.9e-61 204.7 2.3 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 PVD39441.1 - 2.7e-11 43.4 1.7 3.7e-11 42.9 0.5 1.9 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit Acyltransferase PF01553.21 PVD39441.1 - 0.013 15.1 0.0 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 Acyltransferase KDGP_aldolase PF07071.11 PVD39441.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 KDGP aldolase CUB PF00431.20 PVD39442.1 - 5.5e-09 36.4 0.2 4.9e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 CUB domain Lysozyme_like PF13702.6 PVD39443.1 - 1.3 8.7 5.3 0.33 10.6 2.1 1.7 2 0 0 2 2 2 0 Lysozyme-like CUB PF00431.20 PVD39444.1 - 7.2e-08 32.8 0.0 3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 CUB domain 7tm_1 PF00001.21 PVD39445.1 - 1.7e-29 103.0 6.6 2.8e-15 56.4 3.1 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 PVD39445.1 - 4.8e-06 26.1 9.5 0.0007 19.0 0.2 2.5 2 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 PVD39445.1 - 7.6e-06 25.5 1.0 7.6e-06 25.5 1.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1467 PF07330.12 PVD39445.1 - 0.013 15.4 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) SpoIIIAH PF12685.7 PVD39446.1 - 0.075 12.9 10.4 0.089 12.6 10.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Atrophin-1 PF03154.15 PVD39446.1 - 0.11 10.7 23.4 0.14 10.4 23.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family NARP1 PF12569.8 PVD39446.1 - 0.2 10.6 20.4 0.23 10.3 20.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Eapp_C PF10238.9 PVD39446.1 - 0.25 11.4 11.1 0.33 11.0 11.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Vfa1 PF08432.10 PVD39446.1 - 0.37 11.1 17.1 0.41 11.0 17.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HDA2-3 PF11496.8 PVD39446.1 - 0.42 9.7 6.3 0.54 9.4 6.3 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.6 PVD39446.1 - 0.44 10.3 21.7 3.5 7.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain RR_TM4-6 PF06459.12 PVD39446.1 - 0.67 9.7 14.6 0.69 9.7 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-N PF05238.13 PVD39446.1 - 0.73 9.1 11.9 0.76 9.0 11.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Hydin_ADK PF17213.3 PVD39446.1 - 0.81 9.9 7.4 0.98 9.7 7.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 PVD39446.1 - 0.89 8.3 13.6 0.95 8.2 13.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF3_subunit PF08597.10 PVD39446.1 - 0.98 9.3 21.1 1.2 9.1 21.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase_fungal PF17667.1 PVD39446.1 - 1 8.1 9.9 1.1 7.9 9.9 1.0 1 0 0 1 1 1 0 Fungal protein kinase SRP-alpha_N PF04086.13 PVD39446.1 - 1.3 8.9 17.3 1.4 8.7 17.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RNA_pol_Rpc4 PF05132.14 PVD39446.1 - 1.3 9.4 9.7 1.6 9.2 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 PVD39446.1 - 1.3 9.1 7.7 1.5 8.9 7.7 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 PVD39446.1 - 1.4 7.1 16.1 1.5 7.0 16.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4770 PF15994.5 PVD39446.1 - 1.4 9.1 11.2 1.9 8.7 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) LicD PF04991.13 PVD39446.1 - 1.8 8.6 7.0 1.9 8.5 7.0 1.1 1 0 0 1 1 1 0 LicD family PBP_sp32 PF07222.12 PVD39446.1 - 2 7.8 12.0 2.3 7.6 12.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Paramyxo_ncap PF00973.19 PVD39446.1 - 2.1 7.1 9.3 2.3 7.1 9.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Zip PF02535.22 PVD39446.1 - 2.2 7.4 4.5 2.2 7.4 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 PVD39446.1 - 2.4 8.7 11.4 2.8 8.5 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 PVD39446.1 - 2.7 6.3 9.2 2.9 6.3 9.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 PVD39446.1 - 3 6.6 8.5 3.2 6.5 8.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_polI_A34 PF08208.11 PVD39446.1 - 3.1 7.8 26.4 3.9 7.5 26.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sec62 PF03839.16 PVD39446.1 - 3.4 7.1 13.6 4.1 6.8 13.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 PVD39446.1 - 3.4 7.3 12.9 3.8 7.2 12.9 1.1 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 PVD39446.1 - 3.5 7.4 9.4 4.4 7.0 9.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GBP_C PF02841.14 PVD39446.1 - 4.2 6.7 17.6 4.8 6.5 17.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Neur_chan_memb PF02932.16 PVD39446.1 - 6 6.9 8.9 6.4 6.8 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3464 PF11947.8 PVD39446.1 - 6.9 6.4 17.2 9 6.0 17.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PPL5 PF18168.1 PVD39446.1 - 7 5.8 11.0 7.9 5.7 11.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Coilin_N PF15862.5 PVD39446.1 - 7.7 6.3 22.8 11 5.8 22.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4569 PF15133.6 PVD39446.1 - 9.4 5.9 11.0 11 5.7 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ureide_permease PF07168.11 PVD39446.1 - 9.5 4.9 5.5 9.8 4.8 5.5 1.1 1 0 0 1 1 1 0 Ureide permease Apolipoprotein PF01442.18 PVD39447.1 - 0.0039 17.1 0.9 0.19 11.6 0.1 3.1 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain OrfB_IS605 PF01385.19 PVD39447.1 - 5.3 7.3 20.8 33 4.7 0.6 5.6 4 2 2 6 6 6 0 Probable transposase Apolipoprotein PF01442.18 PVD39448.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATG_C PF09333.11 PVD39448.1 - 0.011 16.0 0.0 21 5.5 0.0 3.5 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain Cytochrom_B562 PF07361.11 PVD39448.1 - 0.15 12.7 0.0 0.41 11.3 0.0 1.8 2 0 0 2 2 2 0 Cytochrome b562 Gln_amidase PF15644.6 PVD39448.1 - 0.17 12.9 0.7 2.2 9.3 0.2 2.7 1 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase LEP503 PF15221.6 PVD39449.1 - 0.1 12.9 0.2 0.33 11.3 0.0 1.7 1 1 1 2 2 2 0 Lens epithelial cell protein LEP503 Pkinase PF00069.25 PVD39451.1 - 1.8e-45 155.4 0.0 3.7e-45 154.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PVD39451.1 - 4.2e-27 95.1 0.0 6.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PVD39451.1 - 3.3e-06 27.2 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PVD39451.1 - 3.9e-05 23.1 0.0 7.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PVD39451.1 - 0.00013 20.9 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PVD39451.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PVD39451.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PVD39451.1 - 0.011 15.3 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 RIO1 family PDZ PF00595.24 PVD39453.1 - 3.2e-12 46.6 0.0 6.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PVD39453.1 - 1e-07 31.6 0.1 2.6e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PVD39453.1 - 1.1e-07 32.0 0.0 5.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 PVD39453.1 - 0.029 14.3 0.9 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease PDZ domain SH3_9 PF14604.6 PVD39455.1 - 1e-45 153.3 1.0 1e-14 54.1 0.2 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 PVD39455.1 - 2.8e-40 135.7 0.0 1.1e-12 47.3 0.0 3.7 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 PVD39455.1 - 1.8e-30 104.4 0.7 7.8e-13 47.9 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 PVD39455.1 - 1e-18 66.9 0.2 2.1e-18 65.9 0.2 1.6 1 0 0 1 1 1 1 Sorbin homologous domain Arm PF00514.23 PVD39458.1 - 2.9e-09 36.6 1.1 3e-06 27.1 0.4 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat IFRD PF05004.13 PVD39458.1 - 0.005 16.0 1.4 0.0091 15.1 1.5 1.4 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_N PF03224.14 PVD39458.1 - 0.01 15.2 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 0 V-ATPase subunit H CLASP_N PF12348.8 PVD39458.1 - 0.041 13.5 0.3 0.079 12.5 0.3 1.5 1 0 0 1 1 1 0 CLASP N terminal PGG PF13962.6 PVD39458.1 - 0.051 13.4 0.1 0.087 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function HEAT_EZ PF13513.6 PVD39458.1 - 0.063 13.8 0.8 0.25 11.9 0.4 2.3 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 PVD39458.1 - 0.064 13.7 0.4 0.33 11.4 0.2 2.2 2 1 0 2 2 2 0 HEAT repeats GPI2 PF06432.11 PVD39458.1 - 0.094 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Cas9_PI PF16595.5 PVD39458.1 - 0.094 12.6 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 Arm PF00514.23 PVD39459.1 - 2.8e-06 27.2 11.2 0.43 10.7 0.1 6.0 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat zf-MIZ PF02891.20 PVD39460.1 - 1.2e-21 76.2 7.2 1.2e-21 76.2 7.2 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PVD39460.1 - 2.1e-05 24.3 3.9 4.6e-05 23.2 3.1 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Zmiz1_N PF18028.1 PVD39461.1 - 5.8e-34 116.4 0.0 9.7e-34 115.7 0.0 1.3 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain DivIC PF04977.15 PVD39463.1 - 0.093 12.5 0.8 1.5 8.7 0.1 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF948 PF06103.11 PVD39463.1 - 0.12 12.7 2.9 0.13 12.5 0.3 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MYO10_CC PF16735.5 PVD39463.1 - 0.3 11.2 3.4 2.9 8.1 0.2 3.3 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain WD40 PF00400.32 PVD39464.1 - 6e-12 45.9 18.2 0.024 15.5 0.0 8.5 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PVD39464.1 - 3.1e-09 37.0 0.0 0.14 12.4 0.0 5.9 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PVD39464.1 - 0.0069 15.4 0.0 15 4.5 0.0 3.6 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-B_dimeris PF09026.10 PVD39464.1 - 0.16 12.4 8.8 0.08 13.3 5.8 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Synaptobrevin PF00957.21 PVD39465.1 - 1.6e-32 111.1 0.6 3.3e-32 110.1 0.6 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PVD39465.1 - 3e-14 52.8 0.0 4.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3671 PF12420.8 PVD39465.1 - 0.0054 16.8 0.1 0.0098 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function Integrase_H2C2 PF17921.1 PVD39465.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain ABC_membrane PF00664.23 PVD39465.1 - 0.0098 15.6 0.8 0.22 11.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region Fzo_mitofusin PF04799.13 PVD39465.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2721 PF11026.8 PVD39465.1 - 0.014 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2207 PF09972.9 PVD39465.1 - 0.025 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 PVD39465.1 - 0.055 13.5 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Dor1 PF04124.12 PVD39465.1 - 0.06 12.0 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family HD_2 PF12917.7 PVD39465.1 - 0.093 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF2937 PF11157.8 PVD39465.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) LAP1C PF05609.12 PVD39465.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4795 PF16043.5 PVD39465.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_11_kDa PF06143.11 PVD39465.1 - 0.15 11.6 1.4 0.36 10.4 1.4 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.9 PVD39465.1 - 0.17 11.8 0.7 0.39 10.6 0.7 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Pox_EPC_I2-L1 PF12575.8 PVD39465.1 - 0.19 11.9 1.9 16 5.8 0.0 2.6 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Ribosomal_S11 PF00411.19 PVD39467.1 - 3.2e-47 159.5 0.8 4e-47 159.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 PVD39467.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) PH_9 PF15410.6 PVD39468.1 - 9.7e-45 151.8 2.2 1.9e-44 150.8 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 PVD39468.1 - 3.1e-43 147.6 0.2 9.1e-43 146.1 0.1 1.8 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 PVD39468.1 - 2.9e-09 37.4 0.1 1.1e-08 35.5 0.1 2.1 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 PVD39468.1 - 0.024 15.0 0.3 0.069 13.5 0.3 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Pyridoxal_deC PF00282.19 PVD39469.1 - 2.2e-17 62.9 0.0 5.3e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 PVD39469.1 - 2.3e-13 49.9 0.0 6.9e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PVD39469.1 - 2e-06 27.4 0.3 2.9e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 PVD39469.1 - 0.014 14.1 0.1 0.028 13.1 0.1 1.4 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 PVD39469.1 - 0.021 13.3 0.1 0.042 12.4 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_18 PF00704.28 PVD39470.1 - 1.6e-81 274.5 0.1 1.9e-81 274.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD39470.1 - 4.1e-09 36.5 4.5 7.1e-09 35.7 4.5 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Chromo PF00385.24 PVD39471.1 - 1.5e-18 66.5 0.2 2.5e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 PVD39471.1 - 4.8e-10 39.0 2.5 9.4e-10 38.0 2.5 1.5 1 0 0 1 1 1 1 CBX family C-terminal motif Tudor-knot PF11717.8 PVD39471.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AT_hook PF02178.19 PVD39471.1 - 2.1 8.5 13.1 0.89 9.6 8.6 3.0 2 0 0 2 2 2 0 AT hook motif Ras PF00071.22 PVD39474.1 - 6.4e-28 97.4 0.1 8.3e-28 97.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD39474.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IPK PF03770.16 PVD39475.1 - 2.2e-50 171.3 0.0 3.8e-50 170.5 0.0 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase p450 PF00067.22 PVD39476.1 - 8e-94 315.0 2.2 5.4e-87 292.5 0.2 2.0 1 1 1 2 2 2 2 Cytochrome P450 Phage_holin_2_4 PF16082.5 PVD39476.1 - 0.028 14.2 0.4 0.058 13.1 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like 7tm_2 PF00002.24 PVD39477.1 - 5.9e-27 94.5 18.4 9.1e-27 93.9 18.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.17 PVD39477.1 - 5.7e-16 58.8 0.0 1.2e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family GAIN PF16489.5 PVD39477.1 - 8.8e-13 48.2 0.0 2.4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Laminin_G_3 PF13385.6 PVD39477.1 - 6.8e-12 45.8 0.2 1.2e-11 44.9 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HRM PF02793.22 PVD39477.1 - 0.0014 18.9 2.4 0.0037 17.5 1.0 2.6 2 0 0 2 2 2 1 Hormone receptor domain GPS PF01825.21 PVD39477.1 - 0.011 16.3 5.9 0.049 14.2 5.9 2.3 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif zf-C2H2 PF00096.26 PVD39478.1 - 4.7e-08 33.1 20.7 0.0011 19.3 5.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PVD39478.1 - 4.2e-06 27.1 29.6 0.0041 17.8 3.3 4.5 4 0 0 4 4 3 3 C2H2-type zinc finger CpXC PF14353.6 PVD39478.1 - 1.2e-05 25.3 1.5 0.055 13.5 0.0 2.6 2 1 0 2 2 2 2 CpXC protein zf-C2H2_2 PF12756.7 PVD39478.1 - 0.0017 18.7 11.3 0.25 11.7 2.5 3.3 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 PVD39478.1 - 0.032 14.2 17.9 0.042 13.9 1.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PVD39478.1 - 0.035 14.6 2.0 0.035 14.6 2.0 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 PVD39478.1 - 0.061 14.0 1.1 5.9 7.6 0.9 3.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PVD39478.1 - 0.65 10.3 9.1 0.86 10.0 1.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 PVD39478.1 - 0.79 9.4 4.8 5.4 6.7 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 PVD39478.1 - 0.95 9.4 7.1 23 5.0 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain ADK_lid PF05191.14 PVD39478.1 - 4.6 7.3 7.1 1.4 8.9 0.5 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-BED PF02892.15 PVD39478.1 - 5.2 7.2 11.9 2.2 8.4 1.5 2.9 3 0 0 3 3 3 0 BED zinc finger zf-C2HE PF16278.5 PVD39478.1 - 8.2 7.0 7.8 71 4.0 0.0 2.7 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Ras PF00071.22 PVD39479.1 - 1.1e-36 125.9 0.0 1.4e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PVD39479.1 - 3e-20 72.6 0.0 4.4e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 PVD39479.1 - 1.4e-07 31.7 0.9 2.5e-07 31.0 0.2 1.8 2 0 0 2 2 2 1 SOCS box Arf PF00025.21 PVD39479.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1284 PF06935.11 PVD39480.1 - 0.053 14.0 4.0 0.086 13.3 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Pribosyl_synth PF14572.6 PVD39482.1 - 8.7e-94 312.7 0.5 1.4e-93 312.0 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 PVD39482.1 - 7.2e-37 125.9 0.1 2.3e-36 124.2 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 PVD39482.1 - 2.9e-07 30.1 0.3 1.1e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HhH-GPD PF00730.25 PVD39483.1 - 8.4e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PVD39483.1 - 9.4e-09 34.7 0.0 3.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 PVD39483.1 - 0.14 12.8 0.0 0.5 11.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_3 PF12836.7 PVD39483.1 - 0.19 12.0 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf-CCHC PF00098.23 PVD39484.1 - 5.1e-06 26.3 3.4 8.8e-06 25.6 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle SCAN PF02023.17 PVD39484.1 - 0.0033 17.2 0.0 0.0093 15.8 0.0 1.7 1 0 0 1 1 1 1 SCAN domain PNMA PF14893.6 PVD39484.1 - 0.11 11.9 0.1 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 PNMA 7TMR-DISM_7TM PF07695.11 PVD39485.1 - 0.0035 17.3 1.1 0.0035 17.3 1.1 1.7 2 0 0 2 2 2 1 7TM diverse intracellular signalling DuoxA PF10204.9 PVD39485.1 - 0.0043 16.1 0.8 0.0043 16.1 0.8 2.0 1 1 0 2 2 2 1 Dual oxidase maturation factor Claudin_3 PF06653.11 PVD39485.1 - 0.051 13.5 1.2 0.051 13.5 1.2 2.0 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Vma12 PF11712.8 PVD39486.1 - 0.73 9.9 2.2 1.7 8.7 2.2 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pox_A14 PF05767.12 PVD39487.1 - 0.00047 20.3 0.9 0.00047 20.3 0.9 1.6 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 HtrL_YibB PF09612.10 PVD39488.1 - 2e-30 106.2 0.0 3.1e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (HtrL_YibB) C1q PF00386.21 PVD39488.1 - 1.3e-06 28.7 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 C1q domain Glycos_transf_N PF04413.16 PVD39488.1 - 0.0033 17.1 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF2583 PF10762.9 PVD39488.1 - 0.19 12.2 0.0 30 5.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) C1q PF00386.21 PVD39489.1 - 6.5e-11 42.5 0.0 9.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 C1q domain Phage_tail_NK PF16532.5 PVD39489.1 - 0.093 12.3 0.3 0.14 11.8 0.2 1.3 1 1 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Gly_transf_sug PF04488.15 PVD39490.1 - 1.8e-07 31.6 0.2 3.7e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PVD39490.1 - 0.00025 20.5 0.4 0.00031 20.2 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PVD39490.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain PMP22_Claudin PF00822.20 PVD39492.1 - 4e-12 46.3 11.5 8.9e-10 38.7 2.7 3.0 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 PVD39492.1 - 0.45 10.4 15.7 0.047 13.6 5.3 2.7 2 1 0 2 2 2 0 Tight junction protein, Claudin-like DuoxA PF10204.9 PVD39492.1 - 0.61 9.0 8.8 1.3 7.9 0.1 2.7 3 0 0 3 3 3 0 Dual oxidase maturation factor Clc-like PF07062.12 PVD39492.1 - 2.9 7.3 17.6 2.1 7.8 0.2 4.2 2 2 2 4 4 4 0 Clc-like Linker_histone PF00538.19 PVD39493.1 - 2e-26 92.1 1.9 3.7e-26 91.3 0.2 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family Claudin_2 PF13903.6 PVD39495.1 - 3.9e-06 26.7 4.5 1.2e-05 25.2 4.4 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PVD39495.1 - 0.00048 20.0 2.9 0.00077 19.4 2.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 PVD39495.1 - 0.0046 16.8 5.7 0.017 15.0 5.1 2.2 1 1 1 2 2 2 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 PVD39496.1 - 5.1e-07 29.7 4.2 7.2e-07 29.2 4.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 PVD39497.1 - 0.34 10.6 2.4 0.67 9.7 2.4 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TAS2R PF05296.13 PVD39497.1 - 6.8 5.7 8.2 0.11 11.6 1.3 1.4 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) DUF3837 PF12939.7 PVD39499.1 - 0.072 13.5 0.2 0.09 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) 7tm_1 PF00001.21 PVD39500.1 - 1.1e-56 192.1 21.7 1.1e-56 192.1 21.7 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 PVD39500.1 - 6.6e-12 45.4 21.4 9.2e-12 44.9 21.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 PVD39500.1 - 2.3e-10 40.5 23.1 4.5e-10 39.6 21.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 PVD39500.1 - 1.5e-09 37.7 16.6 1.5e-09 37.7 16.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 PVD39500.1 - 1e-05 25.0 11.0 1e-05 25.0 11.0 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 PVD39500.1 - 0.00018 21.3 16.5 0.00029 20.7 16.5 1.3 1 0 0 1 1 1 1 Olfactory receptor DUF1772 PF08592.11 PVD39500.1 - 0.44 10.8 5.4 11 6.3 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) PLRV_ORF5 PF01690.17 PVD39501.1 - 0.68 8.6 1.9 0.86 8.3 1.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein VWC PF00093.18 PVD39502.1 - 2.3e-10 40.6 17.9 3.5e-09 36.8 14.8 2.3 2 0 0 2 2 2 2 von Willebrand factor type C domain Amnionless PF14828.6 PVD39502.1 - 0.63 8.8 13.4 0.96 8.2 13.4 1.3 1 0 0 1 1 1 0 Amnionless MerR-DNA-bind PF09278.11 PVD39504.1 - 0.048 14.2 1.1 0.048 14.2 1.1 2.8 2 1 1 3 3 3 0 MerR, DNA binding A1_Propeptide PF07966.12 PVD39504.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 A1 Propeptide Trypsin PF00089.26 PVD39506.1 - 3.8e-86 288.5 7.4 1.8e-51 175.1 0.3 3.0 2 1 1 3 3 3 3 Trypsin Trypsin_2 PF13365.6 PVD39506.1 - 4.5e-10 40.6 3.6 6.5e-05 23.9 0.1 3.0 2 1 1 3 3 3 3 Trypsin-like peptidase domain SRCR PF00530.18 PVD39507.1 - 1.2e-40 138.0 3.2 1.3e-26 93.0 0.2 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Trypsin PF00089.26 PVD39507.1 - 1.2e-08 35.1 0.0 5.8e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 PVD39507.1 - 1.1e-07 32.3 1.3 0.0023 18.5 0.2 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD39507.1 - 3.9e-05 23.8 3.9 0.0043 17.2 0.1 3.6 4 1 0 4 4 4 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD39507.1 - 5.1e-05 23.8 2.5 1.4 9.6 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 PVD39507.1 - 0.00085 19.5 4.3 6.2 7.1 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 PVD39507.1 - 0.0029 17.6 0.0 2.1 8.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain SRCR PF00530.18 PVD39508.1 - 3.2e-05 24.4 0.0 8.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD39508.1 - 0.0019 18.4 1.7 0.0032 17.6 0.1 2.3 3 0 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD39508.1 - 0.0026 18.3 0.1 0.44 11.2 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain PhnH PF05845.12 PVD39508.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) SRCR PF00530.18 PVD39509.1 - 1.3e-15 57.7 0.1 2.2e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD39509.1 - 0.003 18.1 0.0 3.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 PVD39509.1 - 0.0051 17.0 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 PVD39509.1 - 0.013 15.6 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin I-set domain SRCR_2 PF15494.6 PVD39509.1 - 0.033 14.7 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD39509.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Hepsin, SRCR domain SRCR PF00530.18 PVD39510.1 - 2.6e-16 59.9 0.1 1.8e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD39510.1 - 0.0045 17.6 0.0 0.48 11.1 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 PVD39510.1 - 0.007 16.5 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 PVD39510.1 - 0.029 14.4 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.25 PVD39510.1 - 0.078 13.2 0.1 5.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain SRCR PF00530.18 PVD39511.1 - 2.2e-23 82.6 1.5 8.5e-11 42.2 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD39511.1 - 1.2e-11 44.7 0.6 0.00052 20.2 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD39511.1 - 1.1e-08 35.6 3.3 1.2 9.7 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain SRCR_2 PF15494.6 PVD39511.1 - 5.4e-07 30.1 0.3 0.018 15.6 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain I-set PF07679.16 PVD39511.1 - 0.0001 22.3 0.0 2.6 8.2 0.0 4.4 4 0 0 4 4 4 1 Immunoglobulin I-set domain GRAB PF10375.9 PVD39512.1 - 0.16 11.9 1.5 0.44 10.5 1.5 1.7 1 0 0 1 1 1 0 GRIP-related Arf-binding domain SRCR PF00530.18 PVD39515.1 - 4.8e-17 62.3 1.9 1.8e-14 54.1 1.9 2.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD39515.1 - 3.9e-06 27.0 1.0 1.7e-05 25.0 0.0 2.3 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD39515.1 - 7e-05 23.4 0.1 0.13 12.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 PVD39515.1 - 0.00015 21.8 0.0 0.0046 17.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 PVD39515.1 - 0.048 13.8 0.2 3 8.1 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain SRCR PF00530.18 PVD39516.1 - 1.7e-61 205.0 9.1 2.7e-18 66.3 0.1 5.5 4 1 1 5 5 5 4 Scavenger receptor cysteine-rich domain V-set PF07686.17 PVD39516.1 - 3.2e-16 59.4 7.0 0.0017 18.5 0.0 6.3 6 0 0 6 6 6 4 Immunoglobulin V-set domain Ig_3 PF13927.6 PVD39516.1 - 1.3e-10 41.7 16.5 5.8 7.6 0.1 9.3 9 0 0 9 9 9 5 Immunoglobulin domain SRCR_2 PF15494.6 PVD39516.1 - 4.1e-10 40.1 0.6 0.048 14.2 0.1 3.7 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 PVD39516.1 - 0.0025 18.3 0.6 0.92 10.0 0.0 3.6 3 0 0 3 3 3 1 Hepsin, SRCR domain Endonuc_BglI PF14562.6 PVD39516.1 - 0.0026 16.9 0.0 0.63 9.1 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease BglI DUF4832 PF16116.5 PVD39516.1 - 0.01 15.7 0.0 22 4.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4832) SRCR PF00530.18 PVD39519.1 - 7.5e-12 45.6 0.2 1.7e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 PVD39519.1 - 9.6e-05 22.9 0.1 0.0085 16.7 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain SRCR_2 PF15494.6 PVD39519.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain ig PF00047.25 PVD39519.1 - 0.016 15.4 0.7 8.6 6.6 0.1 2.7 2 1 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 PVD39519.1 - 0.027 14.6 0.1 4.1 7.6 0.0 3.0 2 1 0 2 2 2 0 Immunoglobulin V-set domain I-set PF07679.16 PVD39519.1 - 0.032 14.3 0.0 0.77 9.9 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin I-set domain Arena_glycoprot PF00798.18 PVD39521.1 - 0.056 12.1 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Arenavirus glycoprotein Glyco_transf_10 PF00852.19 PVD39522.1 - 1.4e-52 178.0 0.1 2e-52 177.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PVD39522.1 - 3.6e-19 69.3 0.0 1.5e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Hormone_3 PF00159.18 PVD39522.1 - 0.037 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Pancreatic hormone peptide Mucin PF01456.17 PVD39522.1 - 0.38 10.8 23.0 0.74 9.8 23.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 PVD39522.1 - 8.8 4.2 6.8 12 3.8 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SRA1 PF07304.11 PVD39523.1 - 2.1e-09 37.3 0.0 1.4e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 PVD39523.1 - 0.23 12.4 2.0 73 4.5 0.1 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Myosin_head PF00063.21 PVD39524.1 - 5.6e-195 649.5 0.1 5.6e-195 649.5 0.1 2.7 2 1 1 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 PVD39524.1 - 1.7e-153 513.0 289.1 3.3e-152 508.7 289.1 2.0 1 1 0 1 1 1 1 Myosin tail IQ PF00612.27 PVD39524.1 - 4.8e-05 22.8 4.9 0.0012 18.5 0.5 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif ATG16 PF08614.11 PVD39524.1 - 0.00013 22.2 282.4 0.03 14.6 22.5 11.2 1 1 11 12 12 12 5 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 PVD39524.1 - 0.00049 19.5 39.0 0.00049 19.5 39.0 8.5 1 1 6 8 8 8 3 Tropomyosin DUF1664 PF07889.12 PVD39524.1 - 0.78 9.8 159.0 0.1 12.7 8.6 15.0 2 2 13 17 17 17 0 Protein of unknown function (DUF1664) Myosin_N PF02736.19 PVD39526.1 - 1.4e-17 63.2 1.7 2e-17 62.7 1.7 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.21 PVD39526.1 - 5.2e-06 25.0 0.0 7.3e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) ANAPC16 PF17256.2 PVD39527.1 - 0.00012 22.4 0.1 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 16 Hs1pro-1_N PF07231.12 PVD39527.1 - 0.046 13.5 0.2 0.051 13.3 0.2 1.0 1 0 0 1 1 1 0 Hs1pro-1 N-terminus DHHC PF01529.20 PVD39528.1 - 3.2e-30 105.0 13.6 3.2e-30 105.0 13.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SH3_2 PF07653.17 PVD39528.1 - 0.0022 17.6 0.1 0.0056 16.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SNAP PF14938.6 PVD39529.1 - 5.2e-11 42.5 8.6 1.2e-10 41.3 8.6 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 PVD39529.1 - 0.0063 16.8 11.0 0.047 14.0 0.8 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PVD39529.1 - 0.0065 15.9 5.4 0.0099 15.3 4.8 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_11 PF13414.6 PVD39529.1 - 0.012 15.3 0.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 PVD39529.1 - 0.078 13.6 6.5 0.17 12.5 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PVD39529.1 - 0.091 12.6 0.2 28 4.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PVD39529.1 - 0.61 10.3 7.1 5.6 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PVD39529.1 - 1 9.0 5.3 7.1 6.3 4.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain MBOAT PF03062.19 PVD39530.1 - 1.4e-28 100.2 11.3 2.4e-28 99.5 11.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sugar_transport PF06800.12 PVD39530.1 - 0.032 13.6 0.1 0.079 12.3 0.1 1.7 1 0 0 1 1 1 0 Sugar transport protein Glyco_hydro_18 PF00704.28 PVD39531.1 - 2.6e-85 286.9 0.4 3.3e-85 286.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4675 PF15720.5 PVD39532.1 - 0.018 14.8 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Glyco_hydro_18 PF00704.28 PVD39533.1 - 6e-10 39.3 0.0 7.5e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 PVD39534.1 - 2.7e-23 83.2 0.0 3.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 PVD39535.1 - 1.9e-80 270.9 0.8 5.9e-72 243.0 0.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PVD39535.1 - 1e-06 28.8 6.8 1e-06 28.8 6.8 2.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 PVD39536.1 - 3.4e-66 224.1 0.0 9.6e-37 127.4 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 DUF3786 PF12654.7 PVD39536.1 - 0.19 11.3 0.0 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Galactosyl_T PF01762.21 PVD39538.1 - 2.3e-21 76.5 0.0 3.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF2273 PF10031.9 PVD39539.1 - 0.067 13.2 2.3 0.1 12.6 1.4 1.8 1 1 1 2 2 2 0 Small integral membrane protein (DUF2273) Cytochrom_B558a PF05038.13 PVD39539.1 - 1.8 8.1 6.4 4 7.0 0.4 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Phage_HK97_TLTM PF06120.11 PVD39540.1 - 2 7.5 3.4 3.1 6.9 2.6 1.7 2 0 0 2 2 2 0 Tail length tape measure protein Cytochrom_B558a PF05038.13 PVD39540.1 - 3.1 7.3 4.6 2 8.0 1.7 1.9 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Ank_4 PF13637.6 PVD39542.1 - 5.9e-18 65.0 0.2 3e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PVD39542.1 - 2.3e-16 60.1 0.0 3.9e-12 46.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PVD39542.1 - 3.1e-12 46.4 0.1 0.00011 22.5 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PVD39542.1 - 8.1e-12 44.2 0.1 0.0015 18.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 PVD39542.1 - 3.8e-10 39.8 0.9 0.0001 22.5 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) 60KD_IMP PF02096.20 PVD39543.1 - 7.5e-09 35.7 0.3 2.2e-08 34.2 0.3 1.6 1 1 0 1 1 1 1 60Kd inner membrane protein DUF2312 PF10073.9 PVD39543.1 - 0.01 15.4 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1192 PF06698.11 PVD39543.1 - 0.095 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) JIP_LZII PF16471.5 PVD39543.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HMG_box PF00505.19 PVD39544.1 - 6.2e-05 23.3 2.7 6.2e-05 23.3 2.7 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box DUF4806 PF16064.5 PVD39544.1 - 0.00014 22.0 1.5 0.0014 18.9 0.1 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4806) Myb_DNA-bind_5 PF13873.6 PVD39544.1 - 0.0021 18.1 0.7 0.0021 18.1 0.7 3.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain HMG_box_2 PF09011.10 PVD39544.1 - 0.0057 17.2 1.3 0.016 15.8 1.3 1.8 1 0 0 1 1 1 1 HMG-box domain SYF2 PF08231.12 PVD39544.1 - 6.8 7.1 10.4 0.71 10.3 2.4 2.2 1 1 1 2 2 2 0 SYF2 splicing factor EPTP PF03736.17 PVD39545.1 - 6.7e-85 278.9 22.2 1.7e-16 59.9 0.1 7.5 7 0 0 7 7 7 7 EPTP domain Laminin_G_2 PF02210.24 PVD39545.1 - 0.0038 17.8 0.0 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain DUF2818 PF10993.8 PVD39545.1 - 0.35 11.4 7.7 2.8 8.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) CUB PF00431.20 PVD39546.1 - 6.4e-06 26.5 2.2 1.7e-05 25.1 0.4 2.5 2 0 0 2 2 2 1 CUB domain HCO3_cotransp PF00955.21 PVD39547.1 - 6e-199 662.1 15.2 8.8e-199 661.5 15.2 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 PVD39547.1 - 3.3e-95 318.9 0.5 3.3e-95 318.9 0.5 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 PVD39547.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Thioredoxin PF00085.20 PVD39550.1 - 1.4e-78 259.5 0.4 1.1e-22 80.0 0.0 7.1 6 1 1 7 7 7 5 Thioredoxin DnaJ PF00226.31 PVD39550.1 - 2.1e-23 82.2 1.0 4.5e-23 81.1 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain OST3_OST6 PF04756.13 PVD39550.1 - 1.3e-15 57.6 0.9 4.7e-06 26.2 0.0 4.6 4 1 1 5 5 5 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PVD39550.1 - 1e-12 48.5 1.3 0.075 13.5 0.0 6.2 5 1 0 5 5 5 4 Thioredoxin-like domain Thioredoxin_6 PF13848.6 PVD39550.1 - 2.2e-10 40.7 0.0 0.0028 17.6 0.2 5.1 4 3 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PVD39550.1 - 5.6e-08 33.0 0.2 0.13 12.6 0.0 5.3 5 0 0 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 PVD39550.1 - 7e-05 22.9 2.3 0.0019 18.3 0.1 3.4 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.6 PVD39550.1 - 0.00054 19.7 0.4 1.1 9.0 0.1 3.7 4 0 0 4 4 4 2 Thioredoxin TraF PF13728.6 PVD39550.1 - 0.0012 18.7 0.3 0.61 9.9 0.0 3.7 4 0 0 4 4 4 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 PVD39550.1 - 0.0018 18.0 0.4 3.4 7.3 0.0 4.8 5 0 0 5 5 5 1 Thioredoxin Thioredoxin_3 PF13192.6 PVD39550.1 - 0.013 15.6 0.4 1.8 8.6 0.0 3.9 4 0 0 4 4 4 0 Thioredoxin domain Calsequestrin PF01216.17 PVD39550.1 - 0.029 13.4 0.2 2.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Calsequestrin Fibrinogen_C PF00147.18 PVD39551.1 - 1.1e-13 51.5 0.3 1.3e-12 48.0 0.3 2.0 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 PVD39551.1 - 0.0025 17.7 1.8 0.0055 16.6 1.8 1.6 1 0 0 1 1 1 1 PAN domain Fibrinogen_C PF00147.18 PVD39552.1 - 1.7e-40 139.2 0.6 2.4e-40 138.7 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_4 PF14295.6 PVD39552.1 - 0.001 18.9 1.7 0.0029 17.5 1.7 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PVD39552.1 - 0.0024 17.8 0.5 0.006 16.5 0.5 1.6 1 0 0 1 1 1 1 PAN domain Fibrinogen_C PF00147.18 PVD39553.1 - 3.8e-36 125.0 0.4 4.8e-36 124.6 0.4 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Histone PF00125.24 PVD39554.1 - 1.6e-48 164.4 0.3 2e-48 164.1 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PVD39554.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PVD39554.1 - 0.00034 20.9 0.0 0.00051 20.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PVD39554.1 - 0.08 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCSMST1 PF15013.6 PVD39555.1 - 5.3e-25 87.4 0.1 5.3e-25 87.4 0.1 1.5 2 0 0 2 2 2 1 CCSMST1 family Topoisom_bac PF01131.20 PVD39556.1 - 5.6e-95 318.8 0.0 4.1e-66 223.7 0.0 2.1 1 1 1 2 2 2 2 DNA topoisomerase zf-GRF PF06839.12 PVD39556.1 - 1.2e-30 105.4 25.1 3.5e-16 59.0 6.3 3.7 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 PVD39556.1 - 1.2e-17 64.0 0.0 3.7e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 PVD39556.1 - 1.7e-13 50.1 13.3 1.1e-12 47.5 1.7 4.5 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 PVD39556.1 - 0.00098 19.6 0.4 0.00098 19.6 0.4 4.2 5 0 0 5 5 5 1 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 PVD39556.1 - 0.0043 17.0 2.3 0.0043 17.0 2.3 3.3 3 0 0 3 3 3 1 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 PVD39556.1 - 0.017 15.5 1.6 0.017 15.5 1.6 3.0 2 2 1 3 3 3 0 Restriction alleviation protein Lar zf-FPG_IleRS PF06827.14 PVD39556.1 - 0.047 13.6 1.2 13 5.8 0.1 3.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.6 PVD39556.1 - 0.12 12.1 1.6 0.63 9.8 0.2 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Chibby PF14645.6 PVD39557.1 - 3.5e-41 140.3 0.0 4e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Chibby family MFS_1 PF07690.16 PVD39558.1 - 3.9e-10 39.2 10.4 4.4e-10 39.0 10.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 PVD39558.1 - 0.00019 20.8 8.3 0.00025 20.5 8.3 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ECF_trnsprt PF12822.7 PVD39558.1 - 0.017 15.2 10.1 0.021 14.9 10.1 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF4282 PF14110.6 PVD39558.1 - 0.24 12.2 0.1 0.24 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Gram_pos_anchor PF00746.21 PVD39558.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3493 PF11998.8 PVD39558.1 - 3.2 8.0 6.8 16 5.7 0.2 2.6 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF2975 PF11188.8 PVD39558.1 - 4.5 7.2 8.5 4.4 7.2 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) MFS_1 PF07690.16 PVD39560.1 - 1.5e-16 60.3 19.2 1.8e-16 60.0 19.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SF1-HH PF16275.5 PVD39561.1 - 4e-27 94.8 8.9 8.3e-22 77.7 2.4 2.9 2 1 1 3 3 3 2 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 PVD39561.1 - 7.8e-09 35.2 1.4 2.4e-08 33.7 1.4 1.9 1 1 0 1 1 1 1 KH domain zf-CCHC PF00098.23 PVD39561.1 - 0.00069 19.6 0.5 0.0011 19.0 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle UPF0181 PF03701.14 PVD39561.1 - 0.15 11.8 0.1 0.49 10.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Peptidase_S10 PF00450.22 PVD39562.1 - 1.7e-84 284.7 1.7 2.1e-84 284.4 1.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 PVD39562.1 - 0.0069 15.7 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Aa_trans PF01490.18 PVD39563.1 - 2.3e-53 181.4 24.2 6.2e-38 130.6 9.6 3.1 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Aa_trans PF01490.18 PVD39564.1 - 4e-58 197.0 26.2 4.5e-41 140.9 10.1 3.0 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein TMEM43 PF07787.12 PVD39564.1 - 0.19 11.1 0.1 0.63 9.4 0.1 2.0 1 0 0 1 1 1 0 Transmembrane protein 43 RabGAP-TBC PF00566.18 PVD39565.1 - 2.5e-42 145.0 1.8 3.7e-42 144.4 1.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 PVD39565.1 - 4e-08 32.9 0.1 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 2 Rab-binding domain (RBD) BRE1 PF08647.11 PVD39566.1 - 5.7e-16 58.4 9.3 5.7e-16 58.4 9.3 10.8 5 1 6 11 11 11 1 BRE1 E3 ubiquitin ligase Bap31_Bap29_C PF18035.1 PVD39566.1 - 0.015 15.3 1.6 0.015 15.3 1.6 6.6 6 1 1 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF99 PF01949.16 PVD39566.1 - 0.28 10.6 0.0 0.28 10.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF99 NIBRIN_BRCT_II PF16508.5 PVD39566.1 - 7.2 7.0 8.5 4.1 7.8 1.4 3.9 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein MR_MLE_C PF13378.6 PVD39567.1 - 3.4e-49 167.4 0.0 5.1e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 PVD39567.1 - 6.2e-11 42.5 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain OB_NTP_bind PF07717.16 PVD39568.1 - 2.3e-08 34.2 0.1 3.5e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Beta-lactamase PF00144.24 PVD39569.1 - 1e-45 156.5 0.0 1.3e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase PTR2 PF00854.21 PVD39570.1 - 2.6e-91 306.4 13.0 4.2e-91 305.7 9.2 2.5 1 1 1 2 2 2 2 POT family Cytochrome-c551 PF10643.9 PVD39570.1 - 0.18 11.3 1.8 0.42 10.2 1.8 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 RUN PF02759.19 PVD39571.1 - 1.2e-27 96.5 0.0 1.2e-27 96.5 0.0 2.7 3 1 0 3 3 3 1 RUN domain FYVE PF01363.21 PVD39571.1 - 2.2e-20 72.6 12.3 5.5e-20 71.3 12.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger Leucyl-specific PF14795.6 PVD39571.1 - 0.086 12.9 2.4 19 5.4 0.0 3.1 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Trimer_CC PF08954.11 PVD39571.1 - 0.15 11.6 9.7 1.4 8.5 0.3 3.1 3 0 0 3 3 3 0 Trimerisation motif Filament PF00038.21 PVD39571.1 - 0.57 9.7 55.8 0.15 11.6 45.9 3.0 1 1 1 2 2 1 0 Intermediate filament protein KxDL PF10241.9 PVD39571.1 - 1.6 9.1 39.1 0.49 10.7 6.8 6.2 3 2 2 6 6 6 0 Uncharacterized conserved protein AbiGi PF10899.8 PVD39571.1 - 3.4 7.5 9.1 0.13 12.1 2.6 2.0 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin DZR PF12773.7 PVD39571.1 - 3.8 7.6 13.8 14 5.8 3.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 PVD39571.1 - 4.5 7.3 16.4 3.2 7.8 11.3 3.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_5 PF14634.6 PVD39571.1 - 4.9 7.2 20.4 0.37 10.8 15.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zinc-ribbons_6 PF07191.12 PVD39571.1 - 8.9 6.4 13.0 65 3.6 13.0 2.5 1 1 0 1 1 1 0 zinc-ribbons THF_DHG_CYH_C PF02882.19 PVD39573.1 - 6.2e-59 197.9 1.5 8.3e-59 197.5 1.5 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PVD39573.1 - 3.8e-18 65.9 0.1 5.8e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 PVD39573.1 - 0.0031 16.8 0.1 0.0041 16.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 PVD39573.1 - 0.039 14.0 0.7 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain OCD_Mu_crystall PF02423.15 PVD39573.1 - 0.16 10.9 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PTPlike_phytase PF14566.6 PVD39574.1 - 7.8e-15 55.3 0.2 4.8e-07 30.0 0.1 3.4 2 1 0 2 2 2 2 Inositol hexakisphosphate Pyrid_oxidase_2 PF13883.6 PVD39574.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pox_P35 PF03213.14 PVD39575.1 - 0.6 9.3 1.8 0.68 9.1 1.8 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein SSF PF00474.17 PVD39576.1 - 1.3e-11 44.0 5.6 1.3e-11 44.0 5.6 2.5 2 1 1 3 3 3 1 Sodium:solute symporter family RR_TM4-6 PF06459.12 PVD39576.1 - 1.1 9.1 2.7 11 5.7 0.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SecG PF03840.14 PVD39576.1 - 3.9 7.6 10.1 0.62 10.2 0.3 3.4 4 0 0 4 4 4 0 Preprotein translocase SecG subunit SSF PF00474.17 PVD39577.1 - 2.2e-06 26.8 1.4 2.2e-06 26.8 1.4 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 PVD39578.1 - 0.004 16.1 1.5 0.004 16.1 1.5 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family Trns_repr_metal PF02583.17 PVD39578.1 - 0.099 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Peptidase_C2 PF00648.21 PVD39579.1 - 2.7e-96 322.1 0.0 3.9e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD39579.1 - 1.6e-26 93.3 0.0 3.2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 PVD39579.1 - 0.00016 21.3 2.2 0.02 14.8 0.1 4.1 4 1 1 5 5 5 1 EF-hand domain EF-hand_7 PF13499.6 PVD39579.1 - 0.00058 20.3 2.3 0.001 19.5 0.2 2.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 PVD39579.1 - 0.0097 15.4 0.0 0.063 12.9 0.0 2.5 2 0 0 2 2 2 1 EF hand Peptidase_C2 PF00648.21 PVD39580.1 - 5.6e-105 350.6 0.1 7.5e-105 350.2 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD39580.1 - 3.1e-23 82.6 0.0 9.4e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 PVD39580.1 - 1.2e-06 28.0 0.9 0.0022 17.8 0.2 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PVD39580.1 - 0.00011 21.5 0.1 0.00056 19.3 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PVD39580.1 - 0.00067 19.0 0.2 0.002 17.5 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PVD39580.1 - 0.00088 19.7 1.5 0.0016 18.9 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PVD39580.1 - 0.0023 17.7 0.5 3.7 7.5 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain pair KNOX2 PF03791.13 PVD39580.1 - 0.029 13.9 0.2 0.062 12.8 0.2 1.5 1 0 0 1 1 1 0 KNOX2 domain Peptidase_C2 PF00648.21 PVD39581.1 - 3.1e-102 341.6 0.0 4.3e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PVD39581.1 - 1.4e-11 44.8 0.0 2.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III SSF PF00474.17 PVD39582.1 - 6.4e-33 114.2 19.2 9.6e-33 113.6 19.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Phage_holin_5_1 PF06946.11 PVD39582.1 - 2.7 8.4 5.9 11 6.5 0.0 3.7 3 1 1 4 4 4 0 Bacteriophage A118-like holin, Hol118 C1q PF00386.21 PVD39583.1 - 8.1e-18 64.9 0.4 1.2e-17 64.3 0.4 1.3 1 0 0 1 1 1 1 C1q domain SlyX PF04102.12 PVD39583.1 - 0.0039 17.8 1.0 0.0061 17.1 1.0 1.2 1 0 0 1 1 1 1 SlyX PAXX PF15384.6 PVD39583.1 - 0.0054 16.4 0.4 2.7 7.7 0.0 2.1 2 0 0 2 2 2 2 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Prefoldin_2 PF01920.20 PVD39583.1 - 0.018 15.0 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF4618 PF15397.6 PVD39583.1 - 0.05 13.0 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) MscS_porin PF12795.7 PVD39583.1 - 0.06 12.9 3.5 0.08 12.5 3.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain APG17 PF04108.12 PVD39583.1 - 0.12 11.5 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4382 PF14321.6 PVD39583.1 - 0.15 12.3 0.1 0.16 12.2 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4382) HrpB7 PF09486.10 PVD39583.1 - 0.15 12.5 2.1 0.21 12.0 2.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 PVD39583.1 - 0.24 10.7 2.1 0.17 11.2 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OCD_Mu_crystall PF02423.15 PVD39584.1 - 2.2e-79 266.7 2.1 2.5e-79 266.5 2.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 PVD39584.1 - 5.9e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PVD39584.1 - 0.00015 22.2 0.0 0.00068 20.2 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 PVD39584.1 - 0.022 14.8 0.1 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlbA_2 PF04326.14 PVD39585.1 - 2.6e-12 47.1 0.0 3.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Putative DNA-binding domain PKD_channel PF08016.12 PVD39586.1 - 4e-115 384.9 23.8 7e-101 338.0 4.2 2.9 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 PVD39586.1 - 1.2e-10 41.0 25.3 1.4e-05 24.5 5.9 3.2 2 1 1 3 3 3 2 Ion transport protein Fer4_24 PF18109.1 PVD39586.1 - 4.4e-09 36.5 0.2 8.9e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_1 PF00036.32 PVD39586.1 - 3.9e-07 29.1 4.5 0.011 15.2 0.4 3.2 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 PVD39586.1 - 0.0031 17.8 1.1 2.3 8.6 0.1 3.3 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Colicin_V PF02674.16 PVD39586.1 - 0.0062 16.5 2.4 0.0062 16.5 2.4 2.1 2 0 0 2 2 2 1 Colicin V production protein STAT_alpha PF01017.20 PVD39586.1 - 0.013 15.4 0.5 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 STAT protein, all-alpha domain Tma16 PF11176.8 PVD39586.1 - 0.11 12.3 1.4 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Translation machinery-associated protein 16 DUF3810 PF12725.7 PVD39586.1 - 0.35 10.2 20.3 0.13 11.6 0.9 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3810) EF-hand_6 PF13405.6 PVD39586.1 - 0.49 10.5 7.5 3.4 7.9 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 PVD39586.1 - 0.84 10.1 12.7 0.97 9.9 0.9 3.5 2 1 0 3 3 3 0 EF-hand domain pair Tetraspanin PF00335.20 PVD39586.1 - 0.91 9.2 10.8 5.5 6.6 5.9 3.0 2 1 0 2 2 2 0 Tetraspanin family PDR_CDR PF06422.12 PVD39586.1 - 1 9.3 3.4 9.5 6.2 0.5 2.8 2 0 0 2 2 2 0 CDR ABC transporter DHHC PF01529.20 PVD39586.1 - 5.2 7.2 16.2 17 5.6 2.4 3.5 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF2537 PF10801.8 PVD39586.1 - 6.4 7.1 6.8 0.3 11.3 0.1 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF2537) DUF932 PF06067.11 PVD39586.1 - 7.6 6.2 6.0 1.2 8.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF932) Ribosomal_S2 PF00318.20 PVD39587.1 - 7.6e-24 84.1 0.0 1.2e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 PVD39587.1 - 4.7e-14 53.5 18.4 8.1e-14 52.8 18.4 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Alpha-2-MRAP_C PF06401.11 PVD39588.1 - 2.7e-45 155.0 24.2 2.7e-45 155.0 24.2 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 PVD39588.1 - 1e-22 80.3 36.3 1.7e-22 79.6 3.2 4.7 2 1 3 5 5 5 3 Alpha-2-macroglobulin RAP, N-terminal domain DUF1018 PF06252.12 PVD39588.1 - 0.0086 17.1 5.2 0.0088 17.0 2.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1018) DUF2407_C PF13373.6 PVD39588.1 - 0.06 13.5 1.4 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain SlyX PF04102.12 PVD39588.1 - 0.94 10.1 4.5 2.1 9.0 0.2 3.0 2 2 1 3 3 3 0 SlyX DED PF01335.21 PVD39589.1 - 1.9e-12 47.3 4.5 8.4e-11 42.0 3.4 2.3 2 0 0 2 2 2 2 Death effector domain Death PF00531.22 PVD39589.1 - 4e-11 42.9 0.1 9.1e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Death domain FemAB PF02388.16 PVD39589.1 - 0.063 12.1 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 FemAB family S-AdoMet_synt_C PF02773.16 PVD39590.1 - 2.3e-64 215.5 0.1 3.7e-63 211.6 0.0 2.6 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 PVD39590.1 - 1.4e-43 147.9 0.0 3.7e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PVD39590.1 - 7.7e-38 129.2 0.1 1.8e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 PVD39590.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Ank_2 PF12796.7 PVD39591.1 - 1.7e-86 284.9 13.9 1.7e-19 70.2 0.3 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PVD39591.1 - 2.2e-76 251.3 2.8 6.5e-11 42.5 0.0 9.0 6 2 3 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 PVD39591.1 - 4.6e-74 241.9 21.7 6.2e-09 35.9 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 PVD39591.1 - 5.3e-72 229.2 14.0 2.8e-06 27.2 0.0 13.6 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 PVD39591.1 - 2.7e-56 186.9 20.5 3.9e-08 33.4 0.1 11.8 2 2 10 12 12 12 12 Ankyrin repeats (many copies) MutS_II PF05188.17 PVD39591.1 - 0.00018 21.8 2.8 0.00048 20.4 2.8 1.7 1 0 0 1 1 1 1 MutS domain II DUF484 PF04340.12 PVD39591.1 - 0.029 14.1 5.3 0.079 12.6 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF484 FliT PF05400.13 PVD39591.1 - 0.03 15.1 12.9 16 6.4 10.8 3.6 3 0 0 3 3 2 0 Flagellar protein FliT DUF4988 PF16378.5 PVD39591.1 - 0.069 12.8 0.0 2.3 7.8 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function AAA_23 PF13476.6 PVD39591.1 - 0.11 12.9 6.2 0.23 11.9 6.2 1.5 1 0 0 1 1 1 0 AAA domain MCU PF04678.13 PVD39591.1 - 0.31 11.1 2.8 1 9.4 2.8 1.9 1 0 0 1 1 1 0 Mitochondrial calcium uniporter ScdA_N PF04405.14 PVD39591.1 - 0.36 10.5 2.6 9.9 5.9 0.2 4.1 4 0 0 4 4 4 0 Domain of Unknown function (DUF542) UPF0242 PF06785.11 PVD39591.1 - 1.3 9.1 10.9 3 7.9 10.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 PVD39592.1 - 9.1e-61 202.4 4.4 5.9e-17 62.0 0.2 5.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PVD39592.1 - 3.5e-54 179.0 19.8 1.4e-06 28.5 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 PVD39592.1 - 3.9e-52 174.0 0.2 2.3e-09 37.6 0.1 7.4 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PVD39592.1 - 1.7e-42 138.5 11.1 0.00013 22.1 0.1 10.2 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 PVD39592.1 - 3.1e-42 142.1 8.5 2e-10 40.7 0.0 9.4 3 2 6 9 9 9 9 Ankyrin repeats (many copies) KH_1 PF00013.29 PVD39592.1 - 3.3e-16 58.9 1.0 9.8e-16 57.4 1.0 1.9 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 PVD39592.1 - 0.013 15.3 0.0 0.091 12.6 0.0 2.4 2 0 0 2 2 2 0 KH domain PAM2 PF07145.15 PVD39592.1 - 0.047 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region KH_2 PF07650.17 PVD39592.1 - 0.062 13.1 0.4 0.19 11.6 0.4 1.8 1 0 0 1 1 1 0 KH domain DUF3340 PF11818.8 PVD39592.1 - 0.69 10.1 12.7 1.8 8.7 12.7 1.6 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Lectin_C PF00059.21 PVD39594.1 - 5.2e-11 43.2 0.8 1.1e-10 42.2 0.8 1.6 1 0 0 1 1 1 1 Lectin C-type domain ISK_Channel PF02060.15 PVD39594.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel TMEM154 PF15102.6 PVD39594.1 - 0.2 11.5 0.7 1 9.3 0.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family Annexin PF00191.20 PVD39595.1 - 1.1e-62 208.0 2.4 2.7e-21 75.4 0.1 3.5 3 0 0 3 3 3 3 Annexin MRC1 PF09444.10 PVD39595.1 - 0.043 14.3 14.7 0.095 13.2 14.7 1.5 1 0 0 1 1 1 0 MRC1-like domain XRN_N PF03159.18 PVD39595.1 - 0.05 13.0 2.4 0.081 12.3 2.4 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF4246 PF14033.6 PVD39595.1 - 0.15 11.2 5.1 0.24 10.5 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF4587 PF15248.6 PVD39595.1 - 0.17 12.7 5.0 0.49 11.2 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) DUF2273 PF10031.9 PVD39595.1 - 0.39 10.8 2.9 0.81 9.8 2.9 1.6 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF2052 PF09747.9 PVD39595.1 - 1.1 9.4 18.0 0.084 13.0 13.2 1.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 PVD39595.1 - 6.1 6.5 8.9 39 3.9 9.0 2.3 2 0 0 2 2 2 0 FAM176 family Baculo_PEP_C PF04513.12 PVD39595.1 - 7 6.7 7.2 8.9 6.4 4.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTR2 PF00854.21 PVD39596.1 - 6.4e-86 288.6 9.6 1e-85 288.0 9.6 1.3 1 0 0 1 1 1 1 POT family CDC27 PF09507.10 PVD39598.1 - 3.8 6.8 58.3 0.037 13.4 32.0 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MscS_porin PF12795.7 PVD39599.1 - 0.0024 17.5 26.9 0.0024 17.5 26.9 4.4 2 1 2 4 4 4 1 Mechanosensitive ion channel porin domain Filament PF00038.21 PVD39599.1 - 0.0026 17.4 14.1 0.0026 17.4 14.1 4.1 3 1 1 4 4 4 2 Intermediate filament protein CC2-LZ PF16516.5 PVD39599.1 - 0.0038 17.6 19.8 0.0038 17.6 19.8 6.2 3 1 2 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4686 PF15742.5 PVD39599.1 - 0.0065 15.6 14.1 0.0065 15.6 14.1 4.2 2 1 1 4 4 4 1 Domain of unknown function (DUF4686) YabA PF06156.13 PVD39599.1 - 0.013 16.1 8.0 0.013 16.1 8.0 5.9 3 1 2 5 5 5 0 Initiation control protein YabA DUF3600 PF12207.8 PVD39599.1 - 0.034 14.1 0.3 0.093 12.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Streptin-Immun PF11083.8 PVD39599.1 - 0.64 10.5 7.6 0.44 11.0 0.8 3.6 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein NPV_P10 PF05531.12 PVD39599.1 - 3.4 8.2 13.7 2 9.0 1.7 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SMN PF06003.12 PVD39601.1 - 3.4 6.8 11.1 1.4 8.1 1.1 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Adeno_PX PF05829.12 PVD39602.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Pantoate_transf PF02548.15 PVD39602.1 - 0.18 11.1 0.0 0.2 11.0 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase NTR PF01759.21 PVD39604.1 - 0.00057 19.6 0.0 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 UNC-6/NTR/C345C module TIMP PF00965.17 PVD39604.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DAGK_acc PF00609.19 PVD39605.1 - 2.2e-24 86.6 0.0 3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain SWIM PF04434.17 PVD39606.1 - 0.017 14.8 2.2 12 5.7 0.0 3.4 3 0 0 3 3 3 0 SWIM zinc finger MarB PF13999.6 PVD39606.1 - 0.12 12.2 1.7 27 4.7 0.0 4.4 3 2 3 6 6 6 0 MarB protein Jas PF16135.5 PVD39607.1 - 0.036 14.2 0.6 0.059 13.5 0.6 1.4 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Galactosyl_T PF01762.21 PVD39608.1 - 1.1e-14 54.7 0.0 1.9e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase ENTH PF01417.20 PVD39610.1 - 4.6e-30 104.2 0.7 6.8e-30 103.7 0.7 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 PVD39610.1 - 0.00098 18.9 12.3 0.0034 17.2 4.6 2.9 3 0 0 3 3 3 2 Ubiquitin interaction motif ANTH PF07651.16 PVD39610.1 - 0.0012 17.9 0.7 0.0014 17.7 0.7 1.5 1 1 0 1 1 1 1 ANTH domain VHS PF00790.19 PVD39610.1 - 0.028 14.2 0.3 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 VHS domain HMG_box_5 PF14887.6 PVD39610.1 - 0.93 9.5 4.4 4.4 7.3 0.3 3.0 2 1 1 3 3 3 0 HMG (high mobility group) box 5 Mid2 PF04478.12 PVD39611.1 - 0.0054 16.6 3.7 0.0093 15.8 3.7 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.11 PVD39611.1 - 0.0061 16.6 0.3 0.011 15.8 0.3 1.3 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 PVD39611.1 - 0.068 14.1 0.3 0.24 12.3 0.3 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PVD39611.1 - 0.18 11.7 2.0 0.41 10.6 2.0 1.5 1 0 0 1 1 1 0 Syndecan domain Cadherin PF00028.17 PVD39612.1 - 2.9e-218 707.1 56.0 1.5e-17 63.8 0.0 24.8 22 3 3 25 25 25 22 Cadherin domain Cadherin_3 PF16184.5 PVD39612.1 - 2.9e-27 94.8 32.0 0.049 13.6 0.1 15.7 15 0 0 15 15 15 9 Cadherin-like Cadherin_pro PF08758.11 PVD39612.1 - 2.5e-10 40.4 4.0 6.6e-05 23.0 0.0 7.5 10 0 0 10 10 10 2 Cadherin prodomain like Cadherin_2 PF08266.12 PVD39612.1 - 8.6e-10 38.3 0.0 1.8 8.5 0.0 9.8 11 0 0 11 11 11 1 Cadherin-like RET_CLD1 PF17756.1 PVD39612.1 - 4.7e-08 33.4 0.0 2.6 8.4 0.0 6.2 5 1 1 6 6 6 3 RET Cadherin like domain 1 Cadherin_C_2 PF16492.5 PVD39612.1 - 0.026 15.3 0.0 0.13 13.1 0.0 2.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DIPSY PF11763.8 PVD39612.1 - 0.086 13.0 1.6 6.4 7.0 0.3 3.5 3 0 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal C2 PF00168.30 PVD39613.1 - 4.2e-07 30.2 0.0 0.038 14.3 0.0 3.1 3 0 0 3 3 3 2 C2 domain DUF347 PF03988.12 PVD39613.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 PVD39613.1 - 7.7 6.0 6.0 16 5.0 6.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SSF PF00474.17 PVD39614.1 - 2.6e-45 155.0 50.0 1.1e-28 100.3 23.5 3.1 2 2 0 2 2 2 2 Sodium:solute symporter family DUF3094 PF11293.8 PVD39614.1 - 0.02 14.6 5.9 0.23 11.2 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Pomacea_canaliculata-ASM307304v1/GCA_003073045.1_ASM307304v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Pomacea_canaliculata-ASM307304v1/GCA_003073045.1_ASM307304v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Pomacea_canaliculata-ASM307304v1/GCA_003073045.1_ASM307304v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Pomacea_canaliculata-ASM307304v1/GCA_003073045.1_ASM307304v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 19:19:40 2019 # [ok]